Mitch Report

date generated: 2020-10-22

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

##             human        mouse
## A4GALT -14.988939  0.273897484
## AAAS    -2.435804  0.006309781
## AACS    -1.581711  5.546469568
## AAED1   -1.286093 -0.325323373
## AAGAB   -1.722220 -2.514538390
## AAK1    14.833940  1.072727148

Here are some metrics about the input data profile:

Profile metrics

	Profile metrics
num_genes_in_profile	10654
duplicated_genes_present	0
num_profile_genes_in_sets	6218
num_profile_genes_not_in_sets	4436
profile_pearson_correl	NaN
profile_spearman_correl	0.17692

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used: GMT file of genesets: ReactomePathways.gmt

Gene sets metrics

	Gene sets metrics
num_genesets	2408
num_genesets_excluded	1175
num_genesets_included	1233

Gene sets by quadrant

Number of significant gene sets (FDR<0.05)= 376

Interactive enrichment scatterplot

All sets with FDR<0.05. Try hovering over the points.

Top N sets irrespective of FDR. Try hovering over the points.

A heatmap of S values for top results

A plot of effect size versus significance

Significance is the -log2(p.adjustMANOVA) and effect size is the s.dist which is the hypotenuse of the s scores.

Results table

Top N= 50 gene sets

set	setSize	pMANOVA	p.adjustMANOVA	s.dist	s.human	s.mouse	p.human	p.mouse
Metabolism of RNA	567	3.29e-49	4.05e-46	0.380	0.37000	0.0883	2.72e-50	3.91e-04
The citric acid (TCA) cycle and respiratory electron transport	142	4.45e-45	2.75e-42	0.718	-0.20200	-0.6890	3.49e-05	1.02e-45
Processing of Capped Intron-Containing Pre-mRNA	212	5.85e-35	2.40e-32	0.514	0.50000	0.1210	5.18e-36	2.56e-03
Respiratory electron transport	92	1.87e-31	5.78e-29	0.737	-0.17800	-0.7150	3.30e-03	1.81e-32
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.	96	4.84e-31	1.19e-28	0.717	-0.17600	-0.6950	2.89e-03	4.96e-32
Mitochondrial translation	87	1.80e-30	3.54e-28	0.687	0.15800	-0.6680	1.08e-02	4.11e-27
Metabolism	1377	2.01e-30	3.54e-28	0.209	-0.11500	-0.1750	4.70e-12	9.42e-26
Mitochondrial translation elongation	81	4.11e-28	6.33e-26	0.683	0.15800	-0.6640	1.39e-02	4.54e-25
mRNA Splicing	169	4.96e-28	6.79e-26	0.509	0.50100	0.0926	3.50e-29	3.86e-02
Signal Transduction	1401	1.02e-27	1.25e-25	0.171	-0.06420	0.1580	1.03e-04	9.04e-22
mRNA Splicing - Major Pathway	161	1.37e-27	1.54e-25	0.519	0.50800	0.1040	1.02e-28	2.36e-02
Mitochondrial translation initiation	81	1.72e-27	1.77e-25	0.676	0.15200	-0.6590	1.86e-02	1.12e-24
Mitochondrial translation termination	81	2.71e-27	2.57e-25	0.673	0.15600	-0.6540	1.54e-02	2.28e-24
Extracellular matrix organization	194	6.78e-21	5.97e-19	0.365	-0.25300	0.2630	1.41e-09	3.11e-10
Translation	222	3.12e-20	2.56e-18	0.342	0.14400	-0.3100	2.27e-04	2.14e-15
Muscle contraction	120	1.32e-19	1.02e-17	0.502	-0.49300	-0.0934	1.12e-20	7.81e-02
Complex I biogenesis	52	2.28e-19	1.65e-17	0.765	-0.19600	-0.7390	1.45e-02	2.74e-20
Protein localization	136	1.08e-18	7.39e-17	0.453	-0.04580	-0.4510	3.58e-01	1.19e-19
Gene expression (Transcription)	997	1.17e-17	7.57e-16	0.177	0.16600	0.0625	4.98e-18	1.13e-03
Pyruvate metabolism and Citric Acid (TCA) cycle	49	4.72e-16	2.91e-14	0.727	-0.26300	-0.6780	1.45e-03	2.15e-16
Immune System	1225	2.42e-15	1.42e-13	0.137	-0.02410	0.1350	1.69e-01	1.21e-14
Mitochondrial protein import	55	5.13e-14	2.87e-12	0.602	-0.00782	-0.6020	9.20e-01	1.19e-14
Cell Cycle	484	1.10e-13	5.87e-12	0.222	0.19300	0.1100	7.18e-13	4.51e-05
rRNA modification in the nucleus and cytosol	52	1.37e-13	7.04e-12	0.649	0.60000	0.2470	7.07e-14	2.09e-03
rRNA processing in the nucleus and cytosol	143	3.08e-13	1.52e-11	0.380	0.36700	0.0976	4.03e-14	4.47e-02
HIV Life Cycle	122	6.45e-13	3.06e-11	0.424	0.34900	0.2400	2.98e-11	4.84e-06
Late Phase of HIV Life Cycle	112	9.97e-13	4.55e-11	0.439	0.35900	0.2530	5.75e-11	3.97e-06
Cytokine Signaling in Immune system	518	2.97e-12	1.31e-10	0.182	-0.02750	0.1790	2.91e-01	4.94e-12
rRNA processing	154	4.37e-12	1.86e-10	0.342	0.33800	0.0510	4.82e-13	2.76e-01
Major pathway of rRNA processing in the nucleolus and cytosol	134	6.73e-12	2.77e-10	0.370	0.35800	0.0927	8.79e-13	6.47e-02
Signaling by Rho GTPases	269	7.98e-12	3.17e-10	0.251	0.00026	0.2510	9.94e-01	1.96e-12
Transport of Mature mRNA derived from an Intron-Containing Transcript	60	1.03e-11	3.97e-10	0.556	0.52000	0.1970	3.24e-12	8.32e-03
Transport of Mature Transcript to Cytoplasm	69	1.06e-11	3.97e-10	0.522	0.48000	0.2040	5.44e-12	3.45e-03
Signaling by Receptor Tyrosine Kinases	357	1.47e-11	5.32e-10	0.208	-0.04620	0.2030	1.37e-01	6.49e-11
Mitochondrial Fatty Acid Beta-Oxidation	30	2.13e-11	7.50e-10	0.783	-0.33600	-0.7080	1.48e-03	1.94e-11
RNA Polymerase II Transcription	889	3.86e-11	1.32e-09	0.146	0.13800	0.0469	8.38e-12	2.04e-02
Cell Cycle, Mitotic	397	7.59e-11	2.53e-09	0.216	0.18200	0.1160	6.23e-10	8.34e-05
Signaling by GPCR	270	9.23e-11	2.99e-09	0.225	-0.21100	0.0785	2.92e-09	2.74e-02
Innate Immune System	608	1.37e-10	4.33e-09	0.153	-0.04310	0.1460	7.38e-02	1.22e-09
Hemostasis	349	1.51e-10	4.65e-09	0.192	-0.14100	0.1300	7.12e-06	3.65e-05
RNA Polymerase II Pre-transcription Events	69	2.02e-10	6.09e-09	0.498	0.43200	0.2470	5.54e-10	4.05e-04
Nervous system development	395	4.08e-10	1.20e-08	0.177	-0.11700	0.1320	7.65e-05	7.97e-06
Metabolism of non-coding RNA	45	4.91e-10	1.38e-08	0.588	0.55600	0.1920	1.10e-10	2.58e-02
snRNP Assembly	45	4.91e-10	1.38e-08	0.588	0.55600	0.1920	1.10e-10	2.58e-02
Fatty acid metabolism	102	7.30e-10	2.00e-08	0.401	-0.22200	-0.3330	1.08e-04	6.44e-09
RHO GTPase Effectors	173	7.60e-10	2.04e-08	0.295	0.07160	0.2860	1.06e-01	1.03e-10
HIV Infection	187	8.19e-10	2.15e-08	0.297	0.24300	0.1700	1.09e-08	6.69e-05
GPCR downstream signalling	245	8.93e-10	2.29e-08	0.224	-0.20700	0.0834	2.64e-08	2.55e-02
Citric acid cycle (TCA cycle)	21	1.45e-09	3.64e-08	0.833	-0.24300	-0.7970	5.39e-02	2.50e-10
Infectious disease	533	2.47e-09	6.08e-08	0.173	0.09130	0.1470	3.74e-04	9.46e-09

---

Results (complete table)

Click HERE to show results for all gene sets

Complete results

set	setSize	pMANOVA	p.adjustMANOVA	s.dist	s.human	s.mouse	p.human	p.mouse
Metabolism of RNA	567	3.29e-49	4.05e-46	0.38000	0.370000	0.088300	2.72e-50	3.91e-04
The citric acid (TCA) cycle and respiratory electron transport	142	4.45e-45	2.75e-42	0.71800	-0.202000	-0.689000	3.49e-05	1.02e-45
Processing of Capped Intron-Containing Pre-mRNA	212	5.85e-35	2.40e-32	0.51400	0.500000	0.121000	5.18e-36	2.56e-03
Respiratory electron transport	92	1.87e-31	5.78e-29	0.73700	-0.178000	-0.715000	3.30e-03	1.81e-32
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.	96	4.84e-31	1.19e-28	0.71700	-0.176000	-0.695000	2.89e-03	4.96e-32
Mitochondrial translation	87	1.80e-30	3.54e-28	0.68700	0.158000	-0.668000	1.08e-02	4.11e-27
Metabolism	1377	2.01e-30	3.54e-28	0.20900	-0.115000	-0.175000	4.70e-12	9.42e-26
Mitochondrial translation elongation	81	4.11e-28	6.33e-26	0.68300	0.158000	-0.664000	1.39e-02	4.54e-25
mRNA Splicing	169	4.96e-28	6.79e-26	0.50900	0.501000	0.092600	3.50e-29	3.86e-02
Signal Transduction	1401	1.02e-27	1.25e-25	0.17100	-0.064200	0.158000	1.03e-04	9.04e-22
mRNA Splicing - Major Pathway	161	1.37e-27	1.54e-25	0.51900	0.508000	0.104000	1.02e-28	2.36e-02
Mitochondrial translation initiation	81	1.72e-27	1.77e-25	0.67600	0.152000	-0.659000	1.86e-02	1.12e-24
Mitochondrial translation termination	81	2.71e-27	2.57e-25	0.67300	0.156000	-0.654000	1.54e-02	2.28e-24
Extracellular matrix organization	194	6.78e-21	5.97e-19	0.36500	-0.253000	0.263000	1.41e-09	3.11e-10
Translation	222	3.12e-20	2.56e-18	0.34200	0.144000	-0.310000	2.27e-04	2.14e-15
Muscle contraction	120	1.32e-19	1.02e-17	0.50200	-0.493000	-0.093400	1.12e-20	7.81e-02
Complex I biogenesis	52	2.28e-19	1.65e-17	0.76500	-0.196000	-0.739000	1.45e-02	2.74e-20
Protein localization	136	1.08e-18	7.39e-17	0.45300	-0.045800	-0.451000	3.58e-01	1.19e-19
Gene expression (Transcription)	997	1.17e-17	7.57e-16	0.17700	0.166000	0.062500	4.98e-18	1.13e-03
Pyruvate metabolism and Citric Acid (TCA) cycle	49	4.72e-16	2.91e-14	0.72700	-0.263000	-0.678000	1.45e-03	2.15e-16
Immune System	1225	2.42e-15	1.42e-13	0.13700	-0.024100	0.135000	1.69e-01	1.21e-14
Mitochondrial protein import	55	5.13e-14	2.87e-12	0.60200	-0.007820	-0.602000	9.20e-01	1.19e-14
Cell Cycle	484	1.10e-13	5.87e-12	0.22200	0.193000	0.110000	7.18e-13	4.51e-05
rRNA modification in the nucleus and cytosol	52	1.37e-13	7.04e-12	0.64900	0.600000	0.247000	7.07e-14	2.09e-03
rRNA processing in the nucleus and cytosol	143	3.08e-13	1.52e-11	0.38000	0.367000	0.097600	4.03e-14	4.47e-02
HIV Life Cycle	122	6.45e-13	3.06e-11	0.42400	0.349000	0.240000	2.98e-11	4.84e-06
Late Phase of HIV Life Cycle	112	9.97e-13	4.55e-11	0.43900	0.359000	0.253000	5.75e-11	3.97e-06
Cytokine Signaling in Immune system	518	2.97e-12	1.31e-10	0.18200	-0.027500	0.179000	2.91e-01	4.94e-12
rRNA processing	154	4.37e-12	1.86e-10	0.34200	0.338000	0.051000	4.82e-13	2.76e-01
Major pathway of rRNA processing in the nucleolus and cytosol	134	6.73e-12	2.77e-10	0.37000	0.358000	0.092700	8.79e-13	6.47e-02
Signaling by Rho GTPases	269	7.98e-12	3.17e-10	0.25100	0.000260	0.251000	9.94e-01	1.96e-12
Transport of Mature mRNA derived from an Intron-Containing Transcript	60	1.03e-11	3.97e-10	0.55600	0.520000	0.197000	3.24e-12	8.32e-03
Transport of Mature Transcript to Cytoplasm	69	1.06e-11	3.97e-10	0.52200	0.480000	0.204000	5.44e-12	3.45e-03
Signaling by Receptor Tyrosine Kinases	357	1.47e-11	5.32e-10	0.20800	-0.046200	0.203000	1.37e-01	6.49e-11
Mitochondrial Fatty Acid Beta-Oxidation	30	2.13e-11	7.50e-10	0.78300	-0.336000	-0.708000	1.48e-03	1.94e-11
RNA Polymerase II Transcription	889	3.86e-11	1.32e-09	0.14600	0.138000	0.046900	8.38e-12	2.04e-02
Cell Cycle, Mitotic	397	7.59e-11	2.53e-09	0.21600	0.182000	0.116000	6.23e-10	8.34e-05
Signaling by GPCR	270	9.23e-11	2.99e-09	0.22500	-0.211000	0.078500	2.92e-09	2.74e-02
Innate Immune System	608	1.37e-10	4.33e-09	0.15300	-0.043100	0.146000	7.38e-02	1.22e-09
Hemostasis	349	1.51e-10	4.65e-09	0.19200	-0.141000	0.130000	7.12e-06	3.65e-05
RNA Polymerase II Pre-transcription Events	69	2.02e-10	6.09e-09	0.49800	0.432000	0.247000	5.54e-10	4.05e-04
Nervous system development	395	4.08e-10	1.20e-08	0.17700	-0.117000	0.132000	7.65e-05	7.97e-06
Metabolism of non-coding RNA	45	4.91e-10	1.38e-08	0.58800	0.556000	0.192000	1.10e-10	2.58e-02
snRNP Assembly	45	4.91e-10	1.38e-08	0.58800	0.556000	0.192000	1.10e-10	2.58e-02
Fatty acid metabolism	102	7.30e-10	2.00e-08	0.40100	-0.222000	-0.333000	1.08e-04	6.44e-09
RHO GTPase Effectors	173	7.60e-10	2.04e-08	0.29500	0.071600	0.286000	1.06e-01	1.03e-10
HIV Infection	187	8.19e-10	2.15e-08	0.29700	0.243000	0.170000	1.09e-08	6.69e-05
GPCR downstream signalling	245	8.93e-10	2.29e-08	0.22400	-0.207000	0.083400	2.64e-08	2.55e-02
Citric acid cycle (TCA cycle)	21	1.45e-09	3.64e-08	0.83300	-0.243000	-0.797000	5.39e-02	2.50e-10
Infectious disease	533	2.47e-09	6.08e-08	0.17300	0.091300	0.147000	3.74e-04	9.46e-09
Disease	1013	2.76e-09	6.67e-08	0.11900	0.007550	0.119000	6.92e-01	4.46e-10
Cardiac conduction	63	3.41e-09	8.08e-08	0.47400	-0.449000	-0.152000	7.15e-10	3.75e-02
Developmental Biology	588	3.93e-09	9.13e-08	0.14000	-0.070600	0.120000	3.97e-03	8.86e-07
Signaling by Interleukins	278	5.65e-09	1.29e-07	0.20400	-0.054200	0.196000	1.23e-01	2.17e-08
Transcription of the HIV genome	59	1.08e-08	2.43e-07	0.48400	0.436000	0.210000	7.27e-09	5.32e-03
Collagen formation	64	1.90e-08	4.11e-07	0.39200	-0.293000	0.260000	5.24e-05	3.28e-04
Interleukin-4 and Interleukin-13 signaling	64	1.92e-08	4.11e-07	0.40300	-0.130000	0.382000	7.24e-02	1.33e-07
tRNA processing	98	1.94e-08	4.11e-07	0.34700	0.347000	0.021400	3.23e-09	7.14e-01
M Phase	275	3.46e-08	7.24e-07	0.22000	0.195000	0.101000	3.05e-08	4.17e-03
Neutrophil degranulation	292	4.53e-08	9.32e-07	0.18600	-0.060700	0.176000	7.65e-02	2.79e-07
Striated Muscle Contraction	30	6.56e-08	1.33e-06	0.62700	-0.603000	-0.174000	1.10e-08	9.88e-02
Axon guidance	378	7.35e-08	1.46e-06	0.15700	-0.103000	0.119000	6.49e-04	8.57e-05
Collagen biosynthesis and modifying enzymes	48	7.91e-08	1.55e-06	0.43300	-0.330000	0.282000	7.91e-05	7.48e-04
Cell Cycle Checkpoints	191	8.95e-08	1.72e-06	0.25800	0.219000	0.136000	2.07e-07	1.27e-03
SUMOylation of DNA replication proteins	35	9.54e-08	1.81e-06	0.59700	0.499000	0.329000	3.30e-07	7.68e-04
Transport of the SLBP Dependant Mature mRNA	29	1.05e-07	1.96e-06	0.65200	0.556000	0.341000	2.20e-07	1.48e-03
Resolution of Sister Chromatid Cohesion	66	1.13e-07	2.08e-06	0.43300	0.362000	0.237000	3.63e-07	8.69e-04
SUMOylation of ubiquitinylation proteins	31	1.24e-07	2.25e-06	0.62900	0.530000	0.339000	3.33e-07	1.11e-03
Degradation of the extracellular matrix	58	2.07e-07	3.71e-06	0.38300	-0.301000	0.237000	7.56e-05	1.79e-03
RNA polymerase II transcribes snRNA genes	67	2.12e-07	3.73e-06	0.40900	0.386000	0.135000	4.77e-08	5.59e-02
Transport of the SLBP independent Mature mRNA	28	2.57e-07	4.47e-06	0.64400	0.556000	0.325000	3.58e-07	2.96e-03
Interactions of Rev with host cellular proteins	29	2.81e-07	4.81e-06	0.63800	0.499000	0.398000	3.39e-06	2.13e-04
Postmitotic nuclear pore complex (NPC) reformation	24	3.90e-07	6.59e-06	0.69300	0.543000	0.430000	4.11e-06	2.64e-04
Regulation of HSF1-mediated heat shock response	65	4.55e-07	7.58e-06	0.41500	0.361000	0.204000	4.99e-07	4.50e-03
tRNA processing in the nucleus	48	4.82e-07	7.92e-06	0.46900	0.445000	0.149000	1.00e-07	7.53e-02
SUMOylation of RNA binding proteins	38	4.94e-07	8.01e-06	0.54400	0.452000	0.303000	1.46e-06	1.24e-03
Transport of Mature mRNAs Derived from Intronless Transcripts	36	5.04e-07	8.07e-06	0.55800	0.468000	0.302000	1.16e-06	1.70e-03
RNA Polymerase II Transcription Termination	57	6.40e-07	1.01e-05	0.42100	0.408000	0.105000	1.02e-07	1.73e-01
Export of Viral Ribonucleoproteins from Nucleus	26	6.72e-07	1.05e-05	0.65000	0.542000	0.358000	1.69e-06	1.60e-03
Nuclear import of Rev protein	26	6.95e-07	1.07e-05	0.65000	0.533000	0.372000	2.52e-06	1.03e-03
Transport of Ribonucleoproteins into the Host Nucleus	25	7.08e-07	1.08e-05	0.66300	0.541000	0.383000	2.84e-06	9.14e-04
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal	57	7.44e-07	1.10e-05	0.44000	0.353000	0.262000	4.05e-06	6.41e-04
Amplification of signal from the kinetochores	57	7.44e-07	1.10e-05	0.44000	0.353000	0.262000	4.05e-06	6.41e-04
Pyruvate metabolism	26	8.21e-07	1.20e-05	0.62900	-0.228000	-0.586000	4.43e-02	2.27e-07
Gluconeogenesis	23	9.36e-07	1.36e-05	0.68700	-0.535000	-0.430000	8.82e-06	3.57e-04
EML4 and NUDC in mitotic spindle formation	61	9.90e-07	1.41e-05	0.42200	0.326000	0.268000	1.10e-05	3.01e-04
Rev-mediated nuclear export of HIV RNA	28	9.94e-07	1.41e-05	0.62100	0.490000	0.381000	7.25e-06	4.83e-04
Neuronal System	174	1.02e-06	1.44e-05	0.22100	-0.216000	0.043100	9.32e-07	3.29e-01
NS1 Mediated Effects on Host Pathways	31	1.07e-06	1.47e-05	0.59000	0.451000	0.379000	1.37e-05	2.60e-04
SUMOylation of SUMOylation proteins	27	1.07e-06	1.47e-05	0.62300	0.542000	0.307000	1.08e-06	5.86e-03
Transport of Mature mRNA Derived from an Intronless Transcript	35	1.18e-06	1.60e-05	0.54800	0.466000	0.288000	1.87e-06	3.20e-03
Transport of small molecules	410	1.26e-06	1.69e-05	0.16300	-0.136000	-0.090100	2.99e-06	1.94e-03
Mitotic Prometaphase	137	1.32e-06	1.72e-05	0.27500	0.242000	0.132000	1.09e-06	7.97e-03
FCGR3A-mediated phagocytosis	47	1.34e-06	1.72e-05	0.43000	-0.012200	0.429000	8.86e-01	3.57e-07
Leishmania phagocytosis	47	1.34e-06	1.72e-05	0.43000	-0.012200	0.429000	8.86e-01	3.57e-07
Parasite infection	47	1.34e-06	1.72e-05	0.43000	-0.012200	0.429000	8.86e-01	3.57e-07
Post-translational protein modification	1001	1.35e-06	1.72e-05	0.10700	0.059700	0.089000	1.84e-03	3.38e-06
Glycosaminoglycan metabolism	81	1.42e-06	1.79e-05	0.30600	-0.153000	0.265000	1.77e-02	3.76e-05
RHO GTPases Activate Formins	80	1.50e-06	1.87e-05	0.36300	0.222000	0.287000	6.01e-04	9.70e-06
Semaphorin interactions	54	1.55e-06	1.91e-05	0.37300	-0.186000	0.324000	1.81e-02	3.99e-05
Regulation of actin dynamics for phagocytic cup formation	49	1.62e-06	1.97e-05	0.41600	-0.022700	0.415000	7.84e-01	4.98e-07
Fcgamma receptor (FCGR) dependent phagocytosis	67	1.81e-06	2.19e-05	0.34700	-0.065200	0.341000	3.57e-01	1.46e-06
Viral Messenger RNA Synthesis	35	1.86e-06	2.22e-05	0.53700	0.466000	0.266000	1.85e-06	6.51e-03
mRNA 3'-end processing	49	2.16e-06	2.38e-05	0.43900	0.417000	0.139000	4.52e-07	9.37e-02
HIV Transcription Initiation	40	2.16e-06	2.38e-05	0.49200	0.452000	0.194000	7.48e-07	3.39e-02
RNA Polymerase II HIV Promoter Escape	40	2.16e-06	2.38e-05	0.49200	0.452000	0.194000	7.48e-07	3.39e-02
RNA Polymerase II Promoter Escape	40	2.16e-06	2.38e-05	0.49200	0.452000	0.194000	7.48e-07	3.39e-02
RNA Polymerase II Transcription Initiation	40	2.16e-06	2.38e-05	0.49200	0.452000	0.194000	7.48e-07	3.39e-02
RNA Polymerase II Transcription Initiation And Promoter Clearance	40	2.16e-06	2.38e-05	0.49200	0.452000	0.194000	7.48e-07	3.39e-02
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening	40	2.16e-06	2.38e-05	0.49200	0.452000	0.194000	7.48e-07	3.39e-02
Mitotic Anaphase	171	2.16e-06	2.38e-05	0.24500	0.203000	0.136000	4.97e-06	2.23e-03
Mitotic Metaphase and Anaphase	171	2.16e-06	2.38e-05	0.24500	0.203000	0.136000	4.97e-06	2.23e-03
Peroxisomal protein import	49	2.33e-06	2.55e-05	0.43500	-0.117000	-0.419000	1.59e-01	4.06e-07
SUMOylation	137	2.47e-06	2.68e-05	0.27300	0.203000	0.184000	4.46e-05	2.17e-04
EGR2 and SOX10-mediated initiation of Schwann cell myelination	20	2.65e-06	2.84e-05	0.59400	-0.423000	0.417000	1.07e-03	1.25e-03
Vpr-mediated nuclear import of PICs	27	2.78e-06	2.96e-05	0.60700	0.492000	0.355000	9.70e-06	1.40e-03
HCMV Early Events	50	3.27e-06	3.45e-05	0.44300	0.363000	0.255000	9.30e-06	1.85e-03
NEP/NS2 Interacts with the Cellular Export Machinery	25	3.62e-06	3.78e-05	0.62100	0.525000	0.332000	5.54e-06	4.09e-03
Cell surface interactions at the vascular wall	72	3.68e-06	3.82e-05	0.31200	-0.264000	0.167000	1.11e-04	1.47e-02
Interactions of Vpr with host cellular proteins	29	3.82e-06	3.93e-05	0.57700	0.476000	0.327000	9.21e-06	2.33e-03
Smooth Muscle Contraction	32	4.03e-06	4.11e-05	0.48400	-0.474000	0.101000	3.58e-06	3.25e-01
Signaling by NTRKs	113	4.16e-06	4.20e-05	0.25300	-0.091600	0.236000	9.34e-02	1.60e-05
Epigenetic regulation of gene expression	79	4.38e-06	4.39e-05	0.35000	0.279000	0.212000	1.92e-05	1.17e-03
DNA Repair	242	4.63e-06	4.57e-05	0.19300	0.184000	0.057400	9.08e-07	1.26e-01
Glyoxylate metabolism and glycine degradation	20	4.64e-06	4.57e-05	0.66000	-0.172000	-0.637000	1.83e-01	8.05e-07
SLC-mediated transmembrane transport	120	4.81e-06	4.68e-05	0.24600	-0.234000	0.074100	9.69e-06	1.62e-01
SUMOylation of DNA damage response and repair proteins	62	4.82e-06	4.68e-05	0.39200	0.318000	0.230000	1.51e-05	1.77e-03
G alpha (i) signalling events	127	5.21e-06	4.98e-05	0.23800	-0.228000	0.071200	1.01e-05	1.67e-01
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)	23	5.26e-06	4.98e-05	0.63800	0.538000	0.342000	7.84e-06	4.54e-03
Regulation of Glucokinase by Glucokinase Regulatory Protein	23	5.26e-06	4.98e-05	0.63800	0.538000	0.342000	7.84e-06	4.54e-03
Antiviral mechanism by IFN-stimulated genes	64	5.97e-06	5.62e-05	0.38500	0.282000	0.262000	9.80e-05	2.93e-04
Mitochondrial tRNA aminoacylation	18	6.03e-06	5.63e-05	0.62700	0.178000	-0.601000	1.90e-01	9.99e-06
Post-chaperonin tubulin folding pathway	15	7.81e-06	7.24e-05	0.65600	-0.483000	0.444000	1.21e-03	2.89e-03
Formation of RNA Pol II elongation complex	50	9.50e-06	8.60e-05	0.41900	0.371000	0.195000	5.81e-06	1.73e-02
RNA Polymerase II Transcription Elongation	50	9.50e-06	8.60e-05	0.41900	0.371000	0.195000	5.81e-06	1.73e-02
Mitotic Spindle Checkpoint	74	9.54e-06	8.60e-05	0.34600	0.302000	0.169000	7.42e-06	1.22e-02
Platelet activation, signaling and aggregation	169	9.56e-06	8.60e-05	0.19800	-0.093600	0.174000	3.65e-02	1.00e-04
Regulation of TP53 Activity	134	9.70e-06	8.67e-05	0.25600	0.229000	0.115000	5.16e-06	2.14e-02
Ion homeostasis	37	1.01e-05	8.93e-05	0.48000	-0.442000	-0.188000	3.30e-06	4.85e-02
Signaling by MET	53	1.01e-05	8.93e-05	0.37600	0.007420	0.376000	9.26e-01	2.18e-06
Metabolism of proteins	1402	1.03e-05	9.03e-05	0.08240	0.078400	0.025200	2.12e-06	1.28e-01
Metabolism of amino acids and derivatives	226	1.18e-05	1.02e-04	0.19500	-0.075100	-0.180000	5.32e-02	3.70e-06
Transcriptional regulation by small RNAs	39	1.25e-05	1.07e-04	0.47100	0.406000	0.240000	1.19e-05	9.64e-03
Separation of Sister Chromatids	125	1.25e-05	1.07e-04	0.25800	0.242000	0.091500	3.23e-06	7.80e-02
mRNA Splicing - Minor Pathway	47	1.28e-05	1.08e-04	0.40000	0.398000	0.029900	2.33e-06	7.23e-01
SUMOylation of chromatin organization proteins	46	1.28e-05	1.08e-04	0.43900	0.333000	0.286000	9.66e-05	8.03e-04
Formation of tubulin folding intermediates by CCT/TriC	17	1.31e-05	1.10e-04	0.63700	-0.095200	0.630000	4.97e-01	6.85e-06
VEGFA-VEGFR2 Pathway	77	1.43e-05	1.19e-04	0.28700	-0.128000	0.257000	5.26e-02	9.79e-05
SUMO E3 ligases SUMOylate target proteins	131	1.51e-05	1.25e-04	0.25900	0.193000	0.174000	1.48e-04	6.27e-04
Cellular response to heat stress	82	1.72e-05	1.41e-04	0.32500	0.231000	0.229000	3.15e-04	3.40e-04
ECM proteoglycans	37	1.78e-05	1.45e-04	0.40300	-0.270000	0.300000	4.56e-03	1.60e-03
Gene Silencing by RNA	54	2.08e-05	1.69e-04	0.38600	0.352000	0.159000	7.67e-06	4.41e-02
Signaling by NTRK1 (TRKA)	97	2.60e-05	2.09e-04	0.25300	-0.080800	0.240000	1.70e-01	4.64e-05
Mitochondrial calcium ion transport	21	2.93e-05	2.35e-04	0.56900	-0.011200	-0.569000	9.29e-01	6.43e-06
EPH-Ephrin signaling	75	3.13e-05	2.49e-04	0.28600	-0.083500	0.274000	2.12e-01	4.32e-05
NGF-stimulated transcription	32	3.21e-05	2.53e-04	0.44900	-0.050900	0.446000	6.19e-01	1.29e-05
Nuclear Pore Complex (NPC) Disassembly	27	3.53e-05	2.77e-04	0.54500	0.427000	0.338000	1.24e-04	2.35e-03
Branched-chain amino acid catabolism	20	4.02e-05	3.13e-04	0.58500	-0.074400	-0.581000	5.65e-01	6.99e-06
ISG15 antiviral mechanism	59	4.49e-05	3.49e-04	0.36600	0.271000	0.246000	3.29e-04	1.11e-03
Interleukin-10 signaling	11	4.62e-05	3.56e-04	0.72500	-0.252000	0.680000	1.48e-01	9.46e-05
Negative epigenetic regulation of rRNA expression	43	4.89e-05	3.75e-04	0.40900	0.388000	0.127000	1.06e-05	1.50e-01
Transport of inorganic cations/anions and amino acids/oligopeptides	56	5.94e-05	4.52e-04	0.32400	-0.315000	0.072200	4.54e-05	3.51e-01
Signaling by VEGF	83	6.00e-05	4.54e-04	0.25800	-0.120000	0.228000	5.87e-02	3.37e-04
Chromosome Maintenance	68	6.35e-05	4.77e-04	0.32400	0.301000	0.122000	1.85e-05	8.25e-02
Rho GTPase cycle	104	6.75e-05	5.04e-04	0.22900	-0.107000	0.203000	6.03e-02	3.65e-04
Integrin signaling	20	7.37e-05	5.48e-04	0.54200	-0.074700	0.537000	5.63e-01	3.28e-05
Elastic fibre formation	34	7.69e-05	5.67e-04	0.41800	-0.040700	0.416000	6.81e-01	2.76e-05
tRNA Aminoacylation	24	7.84e-05	5.75e-04	0.47600	0.184000	-0.438000	1.18e-01	2.01e-04
Interferon Signaling	120	9.18e-05	6.70e-04	0.24600	0.140000	0.203000	8.42e-03	1.31e-04
Mitotic Prophase	70	9.49e-05	6.89e-04	0.31900	0.273000	0.165000	7.92e-05	1.70e-02
Generic Transcription Pathway	780	9.55e-05	6.89e-04	0.09600	0.091400	0.029100	2.06e-05	1.75e-01
Heparan sulfate/heparin (HS-GAG) metabolism	34	9.86e-05	7.07e-04	0.38600	-0.273000	0.274000	5.94e-03	5.81e-03
Phase 0 - rapid depolarisation	18	1.05e-04	7.49e-04	0.60300	-0.579000	-0.167000	2.11e-05	2.19e-01
NRAGE signals death through JNK	43	1.06e-04	7.50e-04	0.34600	-0.300000	0.172000	6.63e-04	5.15e-02
Metabolism of carbohydrates	205	1.17e-04	8.20e-04	0.16200	-0.154000	0.050100	1.49e-04	2.19e-01
Estrogen-dependent gene expression	75	1.17e-04	8.20e-04	0.30900	0.227000	0.210000	7.09e-04	1.72e-03
Chondroitin sulfate/dermatan sulfate metabolism	38	1.25e-04	8.72e-04	0.36100	-0.242000	0.268000	1.00e-02	4.27e-03
Metabolism of water-soluble vitamins and cofactors	89	1.28e-04	8.87e-04	0.26000	-0.021800	-0.259000	7.23e-01	2.49e-05
MET promotes cell motility	25	1.42e-04	9.75e-04	0.44400	-0.247000	0.369000	3.25e-02	1.42e-03
Non-integrin membrane-ECM interactions	36	1.45e-04	9.90e-04	0.36800	-0.280000	0.239000	3.71e-03	1.31e-02
Death Receptor Signalling	106	1.78e-04	1.21e-03	0.21300	-0.171000	0.127000	2.36e-03	2.45e-02
Cell-Cell communication	72	1.82e-04	1.23e-03	0.25800	-0.154000	0.206000	2.37e-02	2.49e-03
Protein-protein interactions at synapses	41	1.95e-04	1.31e-03	0.34000	-0.198000	0.276000	2.81e-02	2.24e-03
Assembly of collagen fibrils and other multimeric structures	43	1.96e-04	1.31e-03	0.33100	-0.260000	0.205000	3.16e-03	2.01e-02
Mitochondrial biogenesis	66	2.01e-04	1.34e-03	0.30200	-0.071200	-0.293000	3.18e-01	3.83e-05
NCAM signaling for neurite out-growth	38	2.17e-04	1.43e-03	0.36300	-0.350000	0.095900	1.88e-04	3.07e-01
GPVI-mediated activation cascade	18	2.17e-04	1.43e-03	0.57800	0.159000	0.556000	2.42e-01	4.47e-05
Leishmania infection	118	2.31e-04	1.51e-03	0.20300	-0.079100	0.187000	1.39e-01	4.77e-04
Sema4D in semaphorin signaling	23	2.48e-04	1.62e-03	0.44800	-0.246000	0.375000	4.10e-02	1.88e-03
PIP3 activates AKT signaling	212	2.52e-04	1.64e-03	0.16800	0.044500	0.162000	2.66e-01	5.10e-05
TP53 Regulates Transcription of DNA Repair Genes	51	2.64e-04	1.71e-03	0.34400	0.322000	0.121000	6.89e-05	1.36e-01
NoRC negatively regulates rRNA expression	40	2.68e-04	1.72e-03	0.38600	0.366000	0.120000	6.13e-05	1.88e-01
p130Cas linkage to MAPK signaling for integrins	10	2.69e-04	1.72e-03	0.70500	-0.141000	0.690000	4.39e-01	1.56e-04
Metabolism of vitamins and cofactors	126	2.87e-04	1.82e-03	0.21800	-0.071400	-0.206000	1.68e-01	6.88e-05
Vesicle-mediated transport	508	2.91e-04	1.84e-03	0.11400	0.060600	0.096200	2.09e-02	2.48e-04
NCAM1 interactions	21	2.94e-04	1.85e-03	0.49000	-0.487000	0.059100	1.14e-04	6.39e-01
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	62	3.09e-04	1.93e-03	0.29000	-0.005260	0.290000	9.43e-01	8.01e-05
Transcriptional Regulation by TP53	307	3.20e-04	1.99e-03	0.14300	0.125000	0.069600	1.81e-04	3.74e-02
Negative regulation of the PI3K/AKT network	69	3.31e-04	2.05e-03	0.27700	0.014800	0.277000	8.32e-01	7.12e-05
ESR-mediated signaling	126	3.40e-04	2.10e-03	0.22400	0.148000	0.169000	4.34e-03	1.12e-03
Defective B3GALT6 causes EDSP2 and SEMDJL1	14	3.48e-04	2.13e-03	0.56100	-0.455000	0.329000	3.23e-03	3.32e-02
Defective B3GAT3 causes JDSSDHD	14	3.52e-04	2.15e-03	0.56500	-0.495000	0.273000	1.35e-03	7.68e-02
Intracellular signaling by second messengers	244	3.65e-04	2.22e-03	0.14400	-0.012000	0.144000	7.48e-01	1.20e-04
Platelet Aggregation (Plug Formation)	22	3.70e-04	2.24e-03	0.46200	-0.121000	0.446000	3.26e-01	2.98e-04
Membrane Trafficking	486	4.02e-04	2.42e-03	0.11500	0.070200	0.090600	8.87e-03	7.24e-04
RHO GTPases Activate WASPs and WAVEs	31	4.07e-04	2.43e-03	0.42000	0.090300	0.410000	3.85e-01	7.88e-05
Unfolded Protein Response (UPR)	82	4.53e-04	2.70e-03	0.26800	0.127000	0.236000	4.74e-02	2.30e-04
Heme biosynthesis	12	4.57e-04	2.71e-03	0.66600	-0.128000	-0.654000	4.44e-01	8.80e-05
HCMV Infection	68	4.67e-04	2.76e-03	0.29700	0.239000	0.176000	6.59e-04	1.23e-02
Defective B4GALT7 causes EDS, progeroid type	14	4.84e-04	2.84e-03	0.55500	-0.494000	0.254000	1.39e-03	1.00e-01
Cristae formation	10	5.28e-04	3.09e-03	0.68900	0.050400	-0.688000	7.83e-01	1.66e-04
Nuclear Receptor transcription pathway	38	5.40e-04	3.14e-03	0.38300	-0.353000	-0.150000	1.70e-04	1.09e-01
Host Interactions of HIV factors	102	5.44e-04	3.15e-03	0.24100	0.178000	0.163000	1.91e-03	4.59e-03
Diseases of glycosylation	97	5.48e-04	3.16e-03	0.20900	-0.110000	0.178000	6.25e-02	2.57e-03
Regulation of TP53 Activity through Phosphorylation	74	5.93e-04	3.40e-03	0.27500	0.248000	0.121000	2.37e-04	7.31e-02
Telomere Maintenance	56	6.05e-04	3.46e-03	0.31100	0.293000	0.103000	1.51e-04	1.82e-01
A tetrasaccharide linker sequence is required for GAG synthesis	18	6.25e-04	3.55e-03	0.47900	-0.413000	0.242000	2.41e-03	7.51e-02
Chromatin modifying enzymes	180	6.66e-04	3.75e-03	0.18000	0.136000	0.118000	1.71e-03	6.77e-03
Chromatin organization	180	6.66e-04	3.75e-03	0.18000	0.136000	0.118000	1.71e-03	6.77e-03
Nuclear Envelope (NE) Reassembly	59	6.86e-04	3.84e-03	0.31000	0.173000	0.257000	2.15e-02	6.60e-04
Defects in vitamin and cofactor metabolism	17	6.94e-04	3.86e-03	0.50800	0.105000	-0.497000	4.53e-01	3.89e-04
Regulation of pyruvate dehydrogenase (PDH) complex	15	6.96e-04	3.86e-03	0.58800	-0.162000	-0.565000	2.77e-01	1.51e-04
Signaling by PDGF	46	7.00e-04	3.87e-03	0.29600	-0.181000	0.234000	3.36e-02	6.19e-03
Nucleotide Excision Repair	102	7.22e-04	3.98e-03	0.22100	0.218000	0.034900	1.43e-04	5.44e-01
G alpha (12/13) signalling events	54	7.44e-04	4.08e-03	0.27300	-0.232000	0.145000	3.25e-03	6.61e-02
Processing of DNA double-strand break ends	50	8.17e-04	4.46e-03	0.32700	0.295000	0.142000	3.18e-04	8.19e-02
GRB2:SOS provides linkage to MAPK signaling for Integrins	10	8.36e-04	4.54e-03	0.64400	-0.202000	0.611000	2.69e-01	8.20e-04
Visual phototransduction	38	8.57e-04	4.63e-03	0.32000	-0.223000	0.229000	1.73e-02	1.47e-02
HATs acetylate histones	72	9.46e-04	5.09e-03	0.27400	0.229000	0.151000	8.12e-04	2.69e-02
Processing of SMDT1	15	9.53e-04	5.11e-03	0.52300	0.149000	-0.501000	3.18e-01	7.79e-04
Diseases associated with glycosaminoglycan metabolism	31	9.99e-04	5.32e-03	0.35000	-0.236000	0.259000	2.31e-02	1.27e-02
Signal regulatory protein family interactions	10	1.00e-03	5.32e-03	0.61600	-0.412000	0.458000	2.41e-02	1.22e-02
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding	24	1.03e-03	5.45e-03	0.44300	0.067500	0.437000	5.67e-01	2.09e-04
Nuclear Envelope Breakdown	42	1.05e-03	5.51e-03	0.35500	0.303000	0.184000	6.93e-04	3.89e-02
Platelet degranulation	86	1.14e-03	5.98e-03	0.20900	-0.142000	0.153000	2.28e-02	1.46e-02
HS-GAG biosynthesis	18	1.14e-03	5.98e-03	0.45500	-0.292000	0.349000	3.18e-02	1.04e-02
MAPK family signaling cascades	224	1.21e-03	6.27e-03	0.13100	-0.066700	0.113000	8.70e-02	3.88e-03
Neurexins and neuroligins	26	1.27e-03	6.57e-03	0.39000	-0.105000	0.376000	3.54e-01	9.23e-04
p75 NTR receptor-mediated signalling	73	1.29e-03	6.68e-03	0.22400	-0.155000	0.162000	2.24e-02	1.67e-02
Transmission across Chemical Synapses	124	1.36e-03	6.98e-03	0.18400	-0.183000	0.014000	4.33e-04	7.88e-01
Peroxisomal lipid metabolism	22	1.41e-03	7.19e-03	0.45600	-0.095500	-0.446000	4.39e-01	2.93e-04
Glycogen metabolism	23	1.41e-03	7.21e-03	0.46400	-0.415000	-0.208000	5.81e-04	8.46e-02
Prefoldin mediated transfer of substrate to CCT/TriC	22	1.45e-03	7.34e-03	0.46000	0.124000	0.443000	3.16e-01	3.22e-04
Formation of HIV elongation complex in the absence of HIV Tat	38	1.50e-03	7.60e-03	0.35400	0.331000	0.127000	4.16e-04	1.77e-01
Collagen chain trimerization	32	1.57e-03	7.87e-03	0.33500	-0.274000	0.193000	7.45e-03	5.91e-02
Potassium Channels	34	1.57e-03	7.87e-03	0.38000	-0.334000	-0.181000	7.53e-04	6.80e-02
DAG and IP3 signaling	33	1.63e-03	8.13e-03	0.35400	-0.354000	0.005300	4.36e-04	9.58e-01
Diseases of signal transduction by growth factor receptors and second messengers	304	1.68e-03	8.37e-03	0.11400	-0.026400	0.111000	4.33e-01	9.92e-04
DNA Double-Strand Break Repair	109	1.73e-03	8.58e-03	0.21200	0.183000	0.107000	9.98e-04	5.33e-02
MAPK1/MAPK3 signaling	193	1.83e-03	9.05e-03	0.13600	-0.071700	0.116000	8.73e-02	5.80e-03
Glycogen breakdown (glycogenolysis)	14	1.94e-03	9.55e-03	0.56900	-0.538000	-0.184000	4.92e-04	2.34e-01
CaM pathway	27	2.02e-03	9.85e-03	0.38200	-0.381000	0.021000	6.07e-04	8.50e-01
Calmodulin induced events	27	2.02e-03	9.85e-03	0.38200	-0.381000	0.021000	6.07e-04	8.50e-01
Regulation of KIT signaling	14	2.09e-03	1.01e-02	0.50000	-0.224000	0.446000	1.46e-01	3.85e-03
Stimuli-sensing channels	43	2.11e-03	1.02e-02	0.33400	-0.270000	-0.197000	2.23e-03	2.54e-02
Signaling by FGFR	60	2.17e-03	1.04e-02	0.28400	0.186000	0.214000	1.29e-02	4.14e-03
HSP90 chaperone cycle for steroid hormone receptors (SHR)	33	2.17e-03	1.04e-02	0.38000	0.222000	0.308000	2.71e-02	2.18e-03
Syndecan interactions	17	2.24e-03	1.07e-02	0.47300	-0.048400	0.471000	7.30e-01	7.78e-04
MET activates PTK2 signaling	15	2.25e-03	1.07e-02	0.47800	-0.419000	0.231000	5.02e-03	1.21e-01
Nuclear Events (kinase and transcription factor activation)	54	2.30e-03	1.09e-02	0.25200	-0.119000	0.223000	1.31e-01	4.72e-03
Response to elevated platelet cytosolic Ca2+	89	2.30e-03	1.09e-02	0.19400	-0.138000	0.136000	2.42e-02	2.66e-02
HS-GAG degradation	16	2.34e-03	1.10e-02	0.46700	-0.435000	0.171000	2.59e-03	2.37e-01
PI3K/AKT Signaling in Cancer	65	2.42e-03	1.13e-02	0.22700	-0.134000	0.184000	6.31e-02	1.06e-02
Cell death signalling via NRAGE, NRIF and NADE	57	2.65e-03	1.24e-02	0.24100	-0.199000	0.135000	9.38e-03	7.73e-02
O-linked glycosylation	51	2.65e-03	1.24e-02	0.25300	-0.163000	0.195000	4.49e-02	1.64e-02
tRNA modification in the nucleus and cytosol	38	2.67e-03	1.24e-02	0.33200	0.322000	0.081500	5.97e-04	3.85e-01
Glycerophospholipid biosynthesis	82	2.71e-03	1.25e-02	0.23700	-0.136000	-0.194000	3.37e-02	2.40e-03
Metabolism of lipids	494	2.80e-03	1.29e-02	0.09890	-0.067100	-0.072600	1.16e-02	6.34e-03
PERK regulates gene expression	28	2.85e-03	1.31e-02	0.39700	0.355000	0.178000	1.14e-03	1.04e-01
Integrin cell surface interactions	45	2.89e-03	1.32e-02	0.27000	-0.232000	0.139000	7.26e-03	1.08e-01
Synthesis of IP3 and IP4 in the cytosol	19	2.89e-03	1.32e-02	0.42900	-0.416000	0.104000	1.70e-03	4.34e-01
Influenza Infection	107	2.93e-03	1.33e-02	0.20700	0.169000	0.118000	2.56e-03	3.47e-02
CRMPs in Sema3A signaling	13	2.97e-03	1.34e-02	0.50100	-0.253000	0.432000	1.14e-01	7.02e-03
Mitochondrial iron-sulfur cluster biogenesis	12	3.05e-03	1.37e-02	0.57200	-0.074800	-0.567000	6.54e-01	6.73e-04
EPHB-mediated forward signaling	32	3.06e-03	1.37e-02	0.34600	0.019700	0.345000	8.47e-01	7.31e-04
Sema3A PAK dependent Axon repulsion	15	3.08e-03	1.37e-02	0.47000	-0.183000	0.433000	2.20e-01	3.68e-03
Formation of HIV-1 elongation complex containing HIV-1 Tat	36	3.30e-03	1.46e-02	0.34700	0.307000	0.162000	1.45e-03	9.31e-02
HIV Transcription Elongation	36	3.30e-03	1.46e-02	0.34700	0.307000	0.162000	1.45e-03	9.31e-02
Tat-mediated elongation of the HIV-1 transcript	36	3.30e-03	1.46e-02	0.34700	0.307000	0.162000	1.45e-03	9.31e-02
Neurotransmitter receptors and postsynaptic signal transmission	96	3.38e-03	1.49e-02	0.19500	-0.194000	0.010700	1.03e-03	8.57e-01
Ion channel transport	91	3.52e-03	1.54e-02	0.21700	-0.193000	-0.099600	1.48e-03	1.01e-01
Dual incision in TC-NER	60	3.54e-03	1.55e-02	0.25000	0.249000	0.015500	8.46e-04	8.36e-01
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)	66	3.67e-03	1.60e-02	0.22000	-0.101000	0.195000	1.56e-01	6.25e-03
Sema4D induced cell migration and growth-cone collapse	19	3.79e-03	1.65e-02	0.40500	-0.206000	0.349000	1.20e-01	8.49e-03
IRE1alpha activates chaperones	47	3.88e-03	1.68e-02	0.27900	0.012300	0.279000	8.84e-01	9.59e-04
Asparagine N-linked glycosylation	237	3.91e-03	1.69e-02	0.13400	0.055700	0.121000	1.42e-01	1.37e-03
G2/M Checkpoints	106	4.03e-03	1.73e-02	0.20100	0.171000	0.105000	2.38e-03	6.34e-02
RAF/MAP kinase cascade	188	4.16e-03	1.78e-02	0.12800	-0.069500	0.108000	1.02e-01	1.10e-02
PECAM1 interactions	10	4.22e-03	1.79e-02	0.55600	-0.250000	0.497000	1.70e-01	6.54e-03
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)	76	4.22e-03	1.79e-02	0.23700	0.195000	0.135000	3.41e-03	4.23e-02
Attenuation phase	20	4.26e-03	1.81e-02	0.46300	0.329000	0.326000	1.09e-02	1.16e-02
Signaling by FGFR2	52	4.64e-03	1.96e-02	0.28500	0.200000	0.203000	1.26e-02	1.13e-02
HIV elongation arrest and recovery	27	4.82e-03	2.02e-02	0.38900	0.334000	0.199000	2.64e-03	7.36e-02
Pausing and recovery of HIV elongation	27	4.82e-03	2.02e-02	0.38900	0.334000	0.199000	2.64e-03	7.36e-02
Formation of TC-NER Pre-Incision Complex	48	4.87e-03	2.02e-02	0.26700	0.267000	-0.006600	1.39e-03	9.37e-01
Homology Directed Repair	82	4.87e-03	2.02e-02	0.22500	0.186000	0.126000	3.66e-03	4.83e-02
mRNA Capping	26	4.88e-03	2.02e-02	0.37700	0.370000	0.075900	1.11e-03	5.03e-01
Ca-dependent events	29	4.95e-03	2.05e-02	0.33700	-0.334000	0.041700	1.84e-03	6.98e-01
Response of Mtb to phagocytosis	18	5.00e-03	2.06e-02	0.47800	0.273000	0.392000	4.50e-02	4.00e-03
Intra-Golgi and retrograde Golgi-to-ER traffic	148	5.03e-03	2.07e-02	0.16800	0.129000	0.108000	6.87e-03	2.38e-02
Extension of Telomeres	43	5.11e-03	2.09e-02	0.30000	0.281000	0.104000	1.43e-03	2.40e-01
Sealing of the nuclear envelope (NE) by ESCRT-III	20	5.38e-03	2.19e-02	0.37900	-0.279000	0.256000	3.06e-02	4.74e-02
Post-translational protein phosphorylation	63	5.57e-03	2.27e-02	0.21800	-0.086400	0.200000	2.37e-01	6.15e-03
FGFR2 alternative splicing	22	5.85e-03	2.37e-02	0.41100	0.391000	0.125000	1.51e-03	3.09e-01
Amino acid transport across the plasma membrane	20	6.08e-03	2.46e-02	0.37600	-0.303000	0.223000	1.91e-02	8.49e-02
RNA Pol II CTD phosphorylation and interaction with CE	24	6.14e-03	2.47e-02	0.38300	0.376000	0.068300	1.42e-03	5.63e-01
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection	24	6.14e-03	2.47e-02	0.38300	0.376000	0.068300	1.42e-03	5.63e-01
Effects of PIP2 hydrolysis	19	6.23e-03	2.50e-02	0.45800	-0.324000	-0.324000	1.44e-02	1.46e-02
Interleukin-3, Interleukin-5 and GM-CSF signaling	28	6.35e-03	2.53e-02	0.32900	-0.078600	0.319000	4.72e-01	3.48e-03
G-protein mediated events	40	6.38e-03	2.53e-02	0.27600	-0.268000	0.062800	3.35e-03	4.92e-01
Role of LAT2/NTAL/LAB on calcium mobilization	11	6.39e-03	2.53e-02	0.57900	0.200000	0.543000	2.50e-01	1.80e-03
Clathrin-mediated endocytosis	109	6.39e-03	2.53e-02	0.18900	0.098700	0.162000	7.59e-02	3.62e-03
trans-Golgi Network Vesicle Budding	63	6.55e-03	2.58e-02	0.25000	0.157000	0.195000	3.10e-02	7.60e-03
Gap-filling DNA repair synthesis and ligation in TC-NER	59	6.59e-03	2.59e-02	0.24000	0.238000	0.026100	1.57e-03	7.29e-01
Cyclin A/B1/B2 associated events during G2/M transition	17	6.64e-03	2.59e-02	0.47800	0.395000	0.269000	4.83e-03	5.49e-02
rRNA processing in the mitochondrion	11	6.65e-03	2.59e-02	0.54900	-0.037300	-0.548000	8.30e-01	1.65e-03
TP53 Regulates Transcription of Cell Cycle Genes	43	6.77e-03	2.63e-02	0.28600	0.063300	0.278000	4.73e-01	1.60e-03
Constitutive Signaling by Aberrant PI3K in Cancer	38	6.93e-03	2.69e-02	0.27200	-0.122000	0.244000	1.93e-01	9.42e-03
G2/M Transition	153	6.97e-03	2.69e-02	0.15600	0.144000	0.059200	2.17e-03	2.08e-01
Golgi Associated Vesicle Biogenesis	49	6.98e-03	2.69e-02	0.28200	0.210000	0.189000	1.13e-02	2.20e-02
Cell-extracellular matrix interactions	16	6.99e-03	2.69e-02	0.41400	-0.258000	0.323000	7.37e-02	2.54e-02
Pausing and recovery of Tat-mediated HIV elongation	25	7.07e-03	2.70e-02	0.39400	0.300000	0.256000	9.46e-03	2.70e-02
Tat-mediated HIV elongation arrest and recovery	25	7.07e-03	2.70e-02	0.39400	0.300000	0.256000	9.46e-03	2.70e-02
Interaction between L1 and Ankyrins	15	7.21e-03	2.74e-02	0.48100	-0.467000	-0.115000	1.73e-03	4.40e-01
L1CAM interactions	70	7.25e-03	2.75e-02	0.19700	-0.145000	0.134000	3.68e-02	5.28e-02
B-WICH complex positively regulates rRNA expression	28	7.39e-03	2.80e-02	0.37000	0.226000	0.293000	3.83e-02	7.38e-03
Deadenylation-dependent mRNA decay	53	7.71e-03	2.91e-02	0.25400	0.248000	0.055100	1.83e-03	4.88e-01
Signaling by Non-Receptor Tyrosine Kinases	42	7.88e-03	2.95e-02	0.26500	-0.050700	0.260000	5.70e-01	3.60e-03
Signaling by PTK6	42	7.88e-03	2.95e-02	0.26500	-0.050700	0.260000	5.70e-01	3.60e-03
Defects in cobalamin (B12) metabolism	10	7.90e-03	2.95e-02	0.53600	0.138000	-0.518000	4.49e-01	4.56e-03
MET activates RAP1 and RAC1	10	8.67e-03	3.22e-02	0.56200	0.045700	0.560000	8.03e-01	2.16e-03
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways	38	8.68e-03	3.22e-02	0.26500	-0.134000	0.228000	1.53e-01	1.49e-02
Defective EXT1 causes exostoses 1, TRPS2 and CHDS	11	8.83e-03	3.26e-02	0.48600	-0.360000	0.326000	3.86e-02	6.10e-02
Defective EXT2 causes exostoses 2	11	8.83e-03	3.26e-02	0.48600	-0.360000	0.326000	3.86e-02	6.10e-02
Mitotic G2-G2/M phases	155	8.94e-03	3.29e-02	0.15200	0.137000	0.067200	3.44e-03	1.50e-01
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	19	9.27e-03	3.40e-02	0.43100	0.191000	0.386000	1.50e-01	3.59e-03
Toll Like Receptor 4 (TLR4) Cascade	102	9.32e-03	3.41e-02	0.16500	-0.046700	0.158000	4.17e-01	5.82e-03
Voltage gated Potassium channels	11	9.47e-03	3.45e-02	0.54900	-0.529000	-0.150000	2.41e-03	3.89e-01
Transcription-Coupled Nucleotide Excision Repair (TC-NER)	73	9.66e-03	3.51e-02	0.20600	0.206000	0.017200	2.42e-03	7.99e-01
FLT3 Signaling	199	9.85e-03	3.57e-02	0.11400	-0.068700	0.091300	9.63e-02	2.71e-02
Cholesterol biosynthesis	23	1.00e-02	3.61e-02	0.33400	-0.275000	0.188000	2.24e-02	1.18e-01
Infection with Mycobacterium tuberculosis	19	1.00e-02	3.62e-02	0.43400	0.255000	0.351000	5.49e-02	8.02e-03
Diseases associated with O-glycosylation of proteins	33	1.02e-02	3.65e-02	0.27700	-0.187000	0.204000	6.34e-02	4.26e-02
Activation of Matrix Metalloproteinases	11	1.02e-02	3.65e-02	0.47900	-0.307000	0.368000	7.79e-02	3.47e-02
RNA Polymerase III Transcription Initiation From Type 3 Promoter	27	1.06e-02	3.79e-02	0.33800	0.335000	0.044500	2.60e-03	6.89e-01
Class I peroxisomal membrane protein import	20	1.07e-02	3.79e-02	0.37600	0.040200	-0.374000	7.56e-01	3.78e-03
Intrinsic Pathway for Apoptosis	42	1.07e-02	3.79e-02	0.24800	-0.108000	0.223000	2.26e-01	1.23e-02
Ephrin signaling	18	1.07e-02	3.79e-02	0.37600	-0.192000	0.323000	1.58e-01	1.78e-02
XBP1(S) activates chaperone genes	45	1.09e-02	3.85e-02	0.25500	-0.003590	0.255000	9.67e-01	3.16e-03
Signaling by RAF1 mutants	32	1.12e-02	3.96e-02	0.27800	-0.176000	0.216000	8.58e-02	3.47e-02
PLC beta mediated events	39	1.13e-02	3.96e-02	0.26500	-0.260000	0.048400	4.95e-03	6.01e-01
S Phase	144	1.19e-02	4.15e-02	0.15000	0.143000	0.044500	3.17e-03	3.58e-01
RHO GTPases activate PAKs	19	1.21e-02	4.24e-02	0.35900	-0.293000	0.207000	2.72e-02	1.18e-01
Interleukin-1 family signaling	102	1.24e-02	4.34e-02	0.17400	0.040000	0.170000	4.86e-01	3.11e-03
Reduction of cytosolic Ca++ levels	10	1.27e-02	4.40e-02	0.53200	-0.532000	-0.002630	3.59e-03	9.89e-01
RHO GTPases activate PKNs	29	1.28e-02	4.42e-02	0.30500	-0.042400	0.302000	6.93e-01	4.94e-03
Regulation of signaling by CBL	13	1.28e-02	4.42e-02	0.47200	0.033600	0.470000	8.34e-01	3.33e-03
Laminin interactions	20	1.29e-02	4.44e-02	0.35700	-0.339000	0.111000	8.67e-03	3.91e-01
Global Genome Nucleotide Excision Repair (GG-NER)	78	1.30e-02	4.44e-02	0.19400	0.193000	0.023100	3.25e-03	7.24e-01
Activation of gene expression by SREBF (SREBP)	40	1.30e-02	4.44e-02	0.24700	-0.215000	0.122000	1.87e-02	1.82e-01
BBSome-mediated cargo-targeting to cilium	18	1.30e-02	4.45e-02	0.41100	0.401000	0.088600	3.25e-03	5.15e-01
PKA activation	15	1.32e-02	4.47e-02	0.44200	-0.439000	-0.058200	3.28e-03	6.96e-01
Cell junction organization	46	1.32e-02	4.47e-02	0.23100	-0.203000	0.109000	1.71e-02	2.02e-01
SLC transporter disorders	51	1.32e-02	4.47e-02	0.25200	0.103000	0.230000	2.03e-01	4.58e-03
Cellular responses to external stimuli	410	1.32e-02	4.47e-02	0.09190	0.049900	0.077200	8.62e-02	7.94e-03
Signaling by SCF-KIT	32	1.38e-02	4.64e-02	0.28700	-0.044100	0.284000	6.66e-01	5.54e-03
N-Glycan antennae elongation	12	1.38e-02	4.64e-02	0.44400	-0.261000	0.360000	1.18e-01	3.09e-02
G2/M DNA damage checkpoint	49	1.39e-02	4.67e-02	0.26100	0.212000	0.151000	1.02e-02	6.72e-02
Listeria monocytogenes entry into host cells	15	1.41e-02	4.72e-02	0.45600	0.162000	0.426000	2.78e-01	4.25e-03
Signaling by BRAF and RAF fusions	52	1.42e-02	4.73e-02	0.21300	-0.173000	0.124000	3.07e-02	1.22e-01
Toll-like Receptor Cascades	115	1.44e-02	4.78e-02	0.15000	-0.029600	0.147000	5.84e-01	6.55e-03
Diseases of metabolism	154	1.44e-02	4.79e-02	0.13000	-0.126000	0.028000	6.97e-03	5.50e-01
Caspase activation via extrinsic apoptotic signalling pathway	20	1.47e-02	4.85e-02	0.34100	-0.255000	0.226000	4.83e-02	8.05e-02
Triglyceride catabolism	13	1.47e-02	4.86e-02	0.50000	-0.275000	-0.418000	8.66e-02	9.04e-03
Deadenylation of mRNA	24	1.48e-02	4.86e-02	0.36600	0.317000	0.184000	7.24e-03	1.18e-01
Association of TriC/CCT with target proteins during biosynthesis	36	1.52e-02	4.99e-02	0.30300	0.210000	0.217000	2.91e-02	2.41e-02
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	14	1.55e-02	5.08e-02	0.40700	-0.216000	0.346000	1.63e-01	2.52e-02
Negative regulation of MET activity	16	1.56e-02	5.09e-02	0.44000	0.182000	0.401000	2.09e-01	5.47e-03
Formation of the Early Elongation Complex	30	1.58e-02	5.12e-02	0.31800	0.299000	0.108000	4.65e-03	3.05e-01
Formation of the HIV-1 Early Elongation Complex	30	1.58e-02	5.12e-02	0.31800	0.299000	0.108000	4.65e-03	3.05e-01
Activation of ATR in response to replication stress	28	1.60e-02	5.18e-02	0.33100	0.305000	0.127000	5.22e-03	2.43e-01
Signaling by high-kinase activity BRAF mutants	27	1.61e-02	5.20e-02	0.30000	-0.088200	0.287000	4.28e-01	9.94e-03
Platelet calcium homeostasis	18	1.61e-02	5.20e-02	0.39000	-0.389000	-0.030100	4.26e-03	8.25e-01
Biological oxidations	85	1.64e-02	5.28e-02	0.19500	-0.141000	-0.135000	2.49e-02	3.13e-02
Degradation of cysteine and homocysteine	12	1.65e-02	5.28e-02	0.51600	-0.303000	-0.417000	6.93e-02	1.23e-02
Netrin-1 signaling	38	1.66e-02	5.29e-02	0.24500	-0.206000	0.133000	2.78e-02	1.57e-01
Cellular responses to stress	406	1.66e-02	5.30e-02	0.08990	0.049000	0.075400	9.36e-02	9.90e-03
Metabolism of porphyrins	18	1.67e-02	5.32e-02	0.40800	-0.143000	-0.382000	2.93e-01	5.06e-03
Signalling to RAS	16	1.69e-02	5.35e-02	0.37800	-0.328000	0.189000	2.34e-02	1.90e-01
Chaperonin-mediated protein folding	69	1.69e-02	5.35e-02	0.21300	0.106000	0.185000	1.29e-01	8.07e-03
Integration of energy metabolism	72	1.71e-02	5.38e-02	0.19500	-0.194000	-0.021000	4.42e-03	7.59e-01
Cobalamin (Cbl, vitamin B12) transport and metabolism	11	1.73e-02	5.43e-02	0.46400	0.149000	-0.439000	3.92e-01	1.16e-02
tRNA processing in the mitochondrion	11	1.77e-02	5.55e-02	0.48300	0.021200	-0.483000	9.03e-01	5.58e-03
Chondroitin sulfate biosynthesis	14	1.78e-02	5.56e-02	0.40700	-0.155000	0.376000	3.14e-01	1.49e-02
Carnitine metabolism	11	1.80e-02	5.57e-02	0.53200	-0.434000	-0.308000	1.27e-02	7.69e-02
Paradoxical activation of RAF signaling by kinase inactive BRAF	36	1.80e-02	5.57e-02	0.24800	-0.167000	0.184000	8.40e-02	5.68e-02
Signaling by RAS mutants	36	1.80e-02	5.57e-02	0.24800	-0.167000	0.184000	8.40e-02	5.68e-02
Signaling by moderate kinase activity BRAF mutants	36	1.80e-02	5.57e-02	0.24800	-0.167000	0.184000	8.40e-02	5.68e-02
Signaling downstream of RAS mutants	36	1.80e-02	5.57e-02	0.24800	-0.167000	0.184000	8.40e-02	5.68e-02
PRC2 methylates histones and DNA	14	1.82e-02	5.60e-02	0.47000	0.258000	0.393000	9.44e-02	1.09e-02
Myogenesis	26	1.82e-02	5.61e-02	0.29900	-0.279000	0.107000	1.39e-02	3.47e-01
Calnexin/calreticulin cycle	23	1.86e-02	5.70e-02	0.35600	0.124000	0.334000	3.02e-01	5.61e-03
Meiosis	38	1.87e-02	5.71e-02	0.26100	0.261000	0.000451	5.47e-03	9.96e-01
Retinoid metabolism and transport	19	1.87e-02	5.71e-02	0.34000	-0.263000	0.216000	4.76e-02	1.04e-01
DNA Replication	111	1.90e-02	5.78e-02	0.16200	0.153000	0.051300	5.43e-03	3.52e-01
Long-term potentiation	10	1.91e-02	5.81e-02	0.50800	-0.508000	-0.010700	5.46e-03	9.53e-01
Regulation of PTEN gene transcription	58	1.96e-02	5.91e-02	0.21800	0.048500	0.213000	5.24e-01	5.08e-03
Negative regulation of NMDA receptor-mediated neuronal transmission	12	1.96e-02	5.91e-02	0.47000	-0.467000	-0.055400	5.11e-03	7.40e-01
Class B/2 (Secretin family receptors)	33	1.96e-02	5.91e-02	0.30600	-0.236000	-0.194000	1.91e-02	5.35e-02
Positive epigenetic regulation of rRNA expression	41	1.99e-02	5.98e-02	0.27100	0.144000	0.230000	1.11e-01	1.09e-02
Amyloid fiber formation	29	2.08e-02	6.23e-02	0.27100	-0.185000	0.199000	8.54e-02	6.45e-02
RHO GTPases Activate ROCKs	18	2.10e-02	6.28e-02	0.34500	-0.194000	0.286000	1.54e-01	3.60e-02
Golgi-to-ER retrograde transport	89	2.12e-02	6.33e-02	0.18300	0.099000	0.154000	1.07e-01	1.21e-02
Opioid Signalling	64	2.13e-02	6.33e-02	0.20700	-0.200000	-0.051000	5.66e-03	4.81e-01
GAB1 signalosome	12	2.19e-02	6.51e-02	0.42000	-0.243000	0.342000	1.45e-01	4.00e-02
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	13	2.20e-02	6.53e-02	0.41000	-0.167000	0.374000	2.98e-01	1.96e-02
SUMOylation of transcription cofactors	38	2.21e-02	6.53e-02	0.27900	0.228000	0.161000	1.50e-02	8.63e-02
Downstream signal transduction	27	2.22e-02	6.54e-02	0.27900	-0.176000	0.217000	1.14e-01	5.14e-02
Protein folding	75	2.23e-02	6.54e-02	0.19600	0.084000	0.177000	2.09e-01	8.30e-03
Pre-NOTCH Processing in Golgi	14	2.23e-02	6.54e-02	0.40600	-0.398000	0.078400	9.92e-03	6.12e-01
RNA Polymerase III Transcription Initiation	34	2.30e-02	6.74e-02	0.27800	0.272000	0.059000	6.07e-03	5.52e-01
Interleukin-37 signaling	16	2.32e-02	6.77e-02	0.39500	0.027200	0.394000	8.51e-01	6.38e-03
PINK1-PRKN Mediated Mitophagy	17	2.33e-02	6.80e-02	0.35700	0.133000	-0.331000	3.42e-01	1.81e-02
TNFR1-induced proapoptotic signaling	11	2.38e-02	6.92e-02	0.43200	-0.322000	0.288000	6.44e-02	9.82e-02
Retrograde transport at the Trans-Golgi-Network	43	2.38e-02	6.92e-02	0.22100	0.191000	-0.111000	3.05e-02	2.07e-01
Mitophagy	24	2.40e-02	6.93e-02	0.29700	0.134000	-0.265000	2.56e-01	2.49e-02
HCMV Late Events	43	2.42e-02	6.98e-02	0.25800	0.220000	0.134000	1.24e-02	1.29e-01
COPI-dependent Golgi-to-ER retrograde traffic	62	2.42e-02	6.98e-02	0.21700	0.137000	0.169000	6.32e-02	2.18e-02
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer	40	2.43e-02	6.99e-02	0.27000	0.169000	0.210000	6.43e-02	2.16e-02
Inwardly rectifying K+ channels	17	2.51e-02	7.19e-02	0.40800	-0.212000	-0.349000	1.31e-01	1.28e-02
Oxidative Stress Induced Senescence	59	2.53e-02	7.24e-02	0.21300	0.068800	0.202000	3.61e-01	7.48e-03
Assembly Of The HIV Virion	12	2.58e-02	7.36e-02	0.42000	-0.147000	0.394000	3.79e-01	1.82e-02
Collagen degradation	20	2.63e-02	7.48e-02	0.31900	-0.275000	0.163000	3.35e-02	2.08e-01
Triglyceride metabolism	20	2.63e-02	7.48e-02	0.37000	-0.163000	-0.332000	2.07e-01	1.02e-02
Transcriptional Regulation by E2F6	29	2.67e-02	7.58e-02	0.30900	0.268000	0.154000	1.26e-02	1.51e-01
Formation of the cornified envelope	10	2.69e-02	7.61e-02	0.45700	-0.427000	0.164000	1.95e-02	3.70e-01
Molecules associated with elastic fibres	25	2.73e-02	7.70e-02	0.31100	0.033300	0.309000	7.74e-01	7.43e-03
PKA-mediated phosphorylation of CREB	17	2.76e-02	7.78e-02	0.37300	-0.372000	-0.019300	7.86e-03	8.90e-01
Deubiquitination	212	2.77e-02	7.78e-02	0.11600	0.084500	0.080000	3.49e-02	4.58e-02
Activation of NMDA receptors and postsynaptic events	52	2.82e-02	7.90e-02	0.19800	-0.180000	0.082500	2.48e-02	3.04e-01
Mucopolysaccharidoses	11	2.90e-02	8.12e-02	0.42200	-0.335000	0.255000	5.41e-02	1.43e-01
Diseases of carbohydrate metabolism	26	2.92e-02	8.15e-02	0.30600	-0.301000	-0.053000	7.85e-03	6.40e-01
Beta-catenin phosphorylation cascade	15	2.96e-02	8.25e-02	0.42700	0.248000	0.347000	9.67e-02	1.98e-02
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	25	2.98e-02	8.27e-02	0.32500	0.294000	0.138000	1.10e-02	2.33e-01
MyD88-independent TLR4 cascade	83	2.99e-02	8.28e-02	0.15500	-0.070600	0.138000	2.67e-01	2.99e-02
TRIF(TICAM1)-mediated TLR4 signaling	83	2.99e-02	8.28e-02	0.15500	-0.070600	0.138000	2.67e-01	2.99e-02
Metabolism of nucleotides	74	3.02e-02	8.33e-02	0.19300	-0.151000	-0.119000	2.45e-02	7.68e-02
Pre-NOTCH Transcription and Translation	31	3.03e-02	8.33e-02	0.27600	0.034000	0.274000	7.43e-01	8.26e-03
Metabolism of cofactors	16	3.06e-02	8.40e-02	0.40100	-0.152000	-0.371000	2.94e-01	1.02e-02
Pre-NOTCH Expression and Processing	45	3.10e-02	8.49e-02	0.21000	-0.090400	0.189000	2.94e-01	2.82e-02
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases	13	3.14e-02	8.60e-02	0.40100	-0.079400	0.393000	6.20e-01	1.41e-02
EPH-ephrin mediated repulsion of cells	37	3.23e-02	8.80e-02	0.22700	-0.125000	0.190000	1.88e-01	4.58e-02
FCGR3A-mediated IL10 synthesis	25	3.23e-02	8.80e-02	0.28900	-0.284000	0.052000	1.39e-02	6.53e-01
Activation of the pre-replicative complex	27	3.31e-02	8.98e-02	0.30900	0.273000	0.145000	1.40e-02	1.92e-01
Synthesis of DNA	106	3.38e-02	9.15e-02	0.15000	0.147000	0.033400	9.33e-03	5.54e-01
Influenza Viral RNA Transcription and Replication	91	3.40e-02	9.20e-02	0.16400	0.157000	0.048600	9.98e-03	4.24e-01
Signaling by FGFR1	34	3.43e-02	9.25e-02	0.26900	0.089000	0.254000	3.70e-01	1.05e-02
CS/DS degradation	10	3.44e-02	9.26e-02	0.43100	-0.265000	0.340000	1.47e-01	6.24e-02
Diseases associated with the TLR signaling cascade	16	3.49e-02	9.36e-02	0.34300	-0.174000	0.295000	2.28e-01	4.11e-02
Diseases of Immune System	16	3.49e-02	9.36e-02	0.34300	-0.174000	0.295000	2.28e-01	4.11e-02
Nonhomologous End-Joining (NHEJ)	30	3.60e-02	9.63e-02	0.27200	0.271000	0.025000	1.02e-02	8.13e-01
Nephrin family interactions	17	3.61e-02	9.63e-02	0.37900	0.137000	0.353000	3.30e-01	1.17e-02
Transcriptional activation of mitochondrial biogenesis	47	3.62e-02	9.63e-02	0.22200	-0.045300	-0.217000	5.91e-01	1.00e-02
PKA activation in glucagon signalling	14	3.65e-02	9.70e-02	0.40700	-0.397000	-0.090500	1.02e-02	5.58e-01
Signaling by FGFR3	29	3.67e-02	9.73e-02	0.28900	0.099200	0.271000	3.56e-01	1.16e-02
Metabolism of fat-soluble vitamins	22	3.71e-02	9.80e-02	0.28800	-0.235000	0.167000	5.64e-02	1.76e-01
Programmed Cell Death	145	3.73e-02	9.84e-02	0.11400	-0.052200	0.101000	2.80e-01	3.60e-02
Detoxification of Reactive Oxygen Species	26	3.74e-02	9.84e-02	0.29500	-0.291000	-0.047900	1.04e-02	6.72e-01
Negative regulation of FGFR2 signaling	19	3.77e-02	9.92e-02	0.33200	-0.011600	0.332000	9.30e-01	1.23e-02
Factors involved in megakaryocyte development and platelet production	80	3.79e-02	9.94e-02	0.15100	-0.114000	0.098100	7.82e-02	1.30e-01
RNA Polymerase I Promoter Escape	25	3.81e-02	9.95e-02	0.30800	0.292000	0.096700	1.15e-02	4.03e-01
Signalling to ERKs	29	3.81e-02	9.95e-02	0.26000	-0.059000	0.253000	5.82e-01	1.83e-02
p75NTR signals via NF-kB	13	3.82e-02	9.95e-02	0.40300	0.001700	0.403000	9.92e-01	1.19e-02
Abortive elongation of HIV-1 transcript in the absence of Tat	21	3.83e-02	9.95e-02	0.34700	0.285000	0.198000	2.36e-02	1.17e-01
RHO GTPases activate CIT	17	3.84e-02	9.96e-02	0.32900	-0.151000	0.292000	2.80e-01	3.70e-02
Phase I - Functionalization of compounds	39	3.86e-02	1.00e-01	0.25000	-0.226000	-0.106000	1.45e-02	2.50e-01
N-glycan antennae elongation in the medial/trans-Golgi	17	4.01e-02	1.04e-01	0.33000	-0.124000	0.306000	3.76e-01	2.91e-02
ATF4 activates genes in response to endoplasmic reticulum stress	24	4.01e-02	1.04e-01	0.31100	0.296000	0.093600	1.20e-02	4.28e-01
Negative regulation of FGFR3 signaling	19	4.05e-02	1.04e-01	0.34400	0.079500	0.335000	5.49e-01	1.15e-02
Cilium Assembly	158	4.06e-02	1.04e-01	0.12300	0.114000	0.047500	1.39e-02	3.05e-01
Sulfur amino acid metabolism	21	4.15e-02	1.06e-01	0.34300	-0.196000	-0.281000	1.19e-01	2.58e-02
GPCR ligand binding	74	4.16e-02	1.06e-01	0.16900	-0.169000	-0.009760	1.23e-02	8.85e-01
Interleukin receptor SHC signaling	15	4.19e-02	1.07e-01	0.36200	-0.044200	0.359000	7.67e-01	1.60e-02
Sialic acid metabolism	23	4.21e-02	1.07e-01	0.30200	-0.302000	-0.021400	1.23e-02	8.59e-01
G0 and Early G1	23	4.25e-02	1.08e-01	0.32300	0.285000	0.152000	1.82e-02	2.07e-01
Synthesis of PIPs at the Golgi membrane	15	4.29e-02	1.09e-01	0.40400	0.326000	0.239000	2.88e-02	1.10e-01
Apoptosis	135	4.33e-02	1.10e-01	0.11600	-0.047500	0.106000	3.43e-01	3.45e-02
Oncogenic MAPK signaling	68	4.38e-02	1.10e-01	0.15900	-0.111000	0.115000	1.15e-01	1.03e-01
Keratinization	12	4.39e-02	1.10e-01	0.38400	-0.345000	0.170000	3.86e-02	3.09e-01
Sphingolipid de novo biosynthesis	32	4.40e-02	1.10e-01	0.25800	0.036100	0.255000	7.24e-01	1.25e-02
Activation of PPARGC1A (PGC-1alpha) by phosphorylation	10	4.40e-02	1.10e-01	0.49400	-0.379000	-0.317000	3.79e-02	8.24e-02
EPHA-mediated growth cone collapse	13	4.40e-02	1.10e-01	0.37700	-0.103000	0.363000	5.20e-01	2.36e-02
Transcriptional regulation by RUNX1	139	4.43e-02	1.11e-01	0.13300	0.082000	0.105000	9.63e-02	3.34e-02
Notch-HLH transcription pathway	24	4.45e-02	1.11e-01	0.26700	-0.206000	0.171000	8.10e-02	1.48e-01
Transport to the Golgi and subsequent modification	136	4.48e-02	1.11e-01	0.13300	0.066600	0.115000	1.81e-01	2.11e-02
Reproduction	44	4.49e-02	1.12e-01	0.21200	0.212000	-0.007790	1.49e-02	9.29e-01
Cytosolic sensors of pathogen-associated DNA	52	4.60e-02	1.14e-01	0.21100	0.190000	0.091500	1.77e-02	2.54e-01
PTEN Regulation	128	4.67e-02	1.16e-01	0.13700	0.082200	0.110000	1.09e-01	3.22e-02
TAK1 activates NFkB by phosphorylation and activation of IKKs complex	22	4.73e-02	1.17e-01	0.28500	-0.089800	0.270000	4.66e-01	2.82e-02
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA	15	4.76e-02	1.17e-01	0.37700	0.368000	0.081000	1.37e-02	5.87e-01
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	31	4.77e-02	1.18e-01	0.27000	0.108000	0.248000	2.99e-01	1.71e-02
Aquaporin-mediated transport	29	4.79e-02	1.18e-01	0.28700	-0.216000	-0.189000	4.46e-02	7.81e-02
Telomere Extension By Telomerase	19	4.95e-02	1.21e-01	0.32800	0.325000	0.045400	1.43e-02	7.32e-01
Sphingolipid metabolism	64	5.04e-02	1.23e-01	0.16800	-0.036000	0.164000	6.19e-01	2.33e-02
Ion transport by P-type ATPases	34	5.14e-02	1.26e-01	0.24200	-0.241000	-0.026400	1.51e-02	7.90e-01
Basigin interactions	17	5.16e-02	1.26e-01	0.32400	-0.317000	0.068500	2.37e-02	6.25e-01
Presynaptic phase of homologous DNA pairing and strand exchange	29	5.17e-02	1.26e-01	0.26300	0.261000	0.029800	1.51e-02	7.81e-01
Signaling by EGFR	41	5.18e-02	1.26e-01	0.22400	0.043400	0.220000	6.31e-01	1.50e-02
Protein ubiquitination	56	5.19e-02	1.26e-01	0.19600	0.185000	0.064500	1.65e-02	4.04e-01
SARS-CoV Infections	121	5.24e-02	1.26e-01	0.12600	-0.001960	0.126000	9.70e-01	1.71e-02
Glycogen storage diseases	11	5.25e-02	1.26e-01	0.44700	-0.407000	-0.185000	1.94e-02	2.89e-01
G1/S Transition	112	5.25e-02	1.26e-01	0.14100	0.127000	0.062200	2.07e-02	2.56e-01
Meiotic recombination	17	5.27e-02	1.27e-01	0.32500	0.320000	-0.056800	2.25e-02	6.85e-01
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	28	5.32e-02	1.28e-01	0.28600	0.173000	0.228000	1.13e-01	3.72e-02
FRS-mediated FGFR2 signaling	12	5.39e-02	1.29e-01	0.38700	-0.058600	0.382000	7.25e-01	2.19e-02
Regulation of mRNA stability by proteins that bind AU-rich elements	75	5.44e-02	1.30e-01	0.17300	0.150000	0.085700	2.51e-02	2.00e-01
PI-3K cascade:FGFR2	10	5.47e-02	1.30e-01	0.41500	-0.108000	0.401000	5.56e-01	2.81e-02
Unblocking of NMDA receptors, glutamate binding and activation	10	5.50e-02	1.31e-01	0.44600	-0.440000	-0.074100	1.60e-02	6.85e-01
Homologous DNA Pairing and Strand Exchange	30	5.51e-02	1.31e-01	0.25500	0.253000	0.024700	1.64e-02	8.15e-01
Potential therapeutics for SARS	66	5.53e-02	1.31e-01	0.16400	-0.026600	0.162000	7.09e-01	2.30e-02
Adaptive Immune System	477	5.53e-02	1.31e-01	0.06820	0.024200	0.063800	3.72e-01	1.84e-02
Translesion Synthesis by POLH	16	5.62e-02	1.33e-01	0.35000	0.347000	0.051700	1.64e-02	7.20e-01
PI Metabolism	69	5.62e-02	1.33e-01	0.17900	0.090200	0.155000	1.96e-01	2.66e-02
Keratan sulfate/keratin metabolism	22	5.64e-02	1.33e-01	0.26900	-0.169000	0.209000	1.70e-01	9.06e-02
SUMOylation of transcription factors	14	5.66e-02	1.33e-01	0.38700	0.134000	0.363000	3.86e-01	1.86e-02
COPII-mediated vesicle transport	56	5.68e-02	1.33e-01	0.19500	0.181000	0.072700	1.96e-02	3.47e-01
Signaling by FGFR2 IIIa TM	16	5.87e-02	1.37e-01	0.37100	0.305000	0.210000	3.46e-02	1.46e-01
RAF-independent MAPK1/3 activation	21	5.98e-02	1.39e-01	0.27300	-0.157000	0.223000	2.13e-01	7.70e-02
SHC-mediated cascade:FGFR2	10	5.98e-02	1.39e-01	0.41100	-0.091500	0.401000	6.16e-01	2.82e-02
Cellular Senescence	117	6.04e-02	1.40e-01	0.13700	0.075000	0.114000	1.63e-01	3.31e-02
Toll Like Receptor 3 (TLR3) Cascade	82	6.21e-02	1.44e-01	0.13800	-0.071700	0.118000	2.63e-01	6.52e-02
ABC transporters in lipid homeostasis	11	6.25e-02	1.45e-01	0.42500	-0.123000	-0.407000	4.80e-01	1.95e-02
Macroautophagy	98	6.32e-02	1.46e-01	0.12500	0.076300	-0.099300	1.93e-01	9.00e-02
Glucagon signaling in metabolic regulation	23	6.33e-02	1.46e-01	0.29900	-0.274000	-0.119000	2.30e-02	3.25e-01
RET signaling	28	6.36e-02	1.47e-01	0.23300	-0.138000	0.188000	2.07e-01	8.47e-02
Ub-specific processing proteases	145	6.57e-02	1.51e-01	0.12200	0.098800	0.070700	4.06e-02	1.43e-01
RNA Polymerase III Transcription Initiation From Type 2 Promoter	25	6.57e-02	1.51e-01	0.27300	0.270000	0.045100	1.96e-02	6.97e-01
O-linked glycosylation of mucins	21	6.60e-02	1.51e-01	0.26900	-0.140000	0.230000	2.66e-01	6.88e-02
ATF6 (ATF6-alpha) activates chaperone genes	10	6.66e-02	1.52e-01	0.43900	0.117000	0.423000	5.21e-01	2.06e-02
E3 ubiquitin ligases ubiquitinate target proteins	39	6.69e-02	1.53e-01	0.23100	0.198000	0.119000	3.26e-02	2.00e-01
FRS-mediated FGFR3 signaling	12	6.70e-02	1.53e-01	0.39700	0.085500	0.387000	6.08e-01	2.02e-02
Nucleotide salvage	18	6.74e-02	1.53e-01	0.30800	-0.307000	0.019500	2.40e-02	8.86e-01
Recognition of DNA damage by PCNA-containing replication complex	28	6.75e-02	1.53e-01	0.26300	0.252000	0.075700	2.12e-02	4.88e-01
Downstream signaling of activated FGFR1	19	6.82e-02	1.54e-01	0.30900	0.035200	0.307000	7.91e-01	2.07e-02
Activation of G protein gated Potassium channels	14	6.83e-02	1.54e-01	0.38400	-0.201000	-0.327000	1.94e-01	3.42e-02
G protein gated Potassium channels	14	6.83e-02	1.54e-01	0.38400	-0.201000	-0.327000	1.94e-01	3.42e-02
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	14	6.83e-02	1.54e-01	0.38400	-0.201000	-0.327000	1.94e-01	3.42e-02
RAB geranylgeranylation	41	6.84e-02	1.54e-01	0.20600	0.206000	-0.002180	2.29e-02	9.81e-01
DDX58/IFIH1-mediated induction of interferon-alpha/beta	52	6.89e-02	1.55e-01	0.17400	-0.054400	0.165000	4.98e-01	3.97e-02
Processing of Capped Intronless Pre-mRNA	25	6.91e-02	1.55e-01	0.27900	0.264000	0.090600	2.26e-02	4.33e-01
Mitotic G1 phase and G1/S transition	127	6.94e-02	1.55e-01	0.12900	0.099800	0.081600	5.29e-02	1.13e-01
p38MAPK events	12	7.03e-02	1.57e-01	0.36900	-0.366000	0.052200	2.84e-02	7.55e-01
Synthesis of PIPs at the early endosome membrane	16	7.08e-02	1.58e-01	0.35200	0.152000	0.318000	2.92e-01	2.78e-02
YAP1- and WWTR1 (TAZ)-stimulated gene expression	11	7.17e-02	1.59e-01	0.36500	-0.300000	0.208000	8.53e-02	2.33e-01
Keratan sulfate biosynthesis	17	7.17e-02	1.59e-01	0.29200	-0.198000	0.215000	1.59e-01	1.25e-01
Post NMDA receptor activation events	44	7.17e-02	1.59e-01	0.19100	-0.188000	0.034700	3.12e-02	6.91e-01
Interleukin-6 signaling	10	7.20e-02	1.59e-01	0.38300	-0.202000	0.325000	2.68e-01	7.49e-02
Telomere C-strand (Lagging Strand) Synthesis	30	7.29e-02	1.61e-01	0.25300	0.237000	0.086900	2.46e-02	4.11e-01
Ovarian tumor domain proteases	31	7.29e-02	1.61e-01	0.24800	0.080000	0.234000	4.41e-01	2.40e-02
Biotin transport and metabolism	10	7.34e-02	1.62e-01	0.41400	-0.020100	-0.414000	9.12e-01	2.34e-02
Glutathione conjugation	21	7.40e-02	1.63e-01	0.31000	-0.253000	-0.180000	4.50e-02	1.53e-01
Signaling by Nuclear Receptors	175	7.48e-02	1.64e-01	0.10800	0.058200	0.090600	1.86e-01	3.95e-02
Inflammasomes	12	7.49e-02	1.64e-01	0.34500	-0.219000	0.267000	1.90e-01	1.10e-01
Deposition of new CENPA-containing nucleosomes at the centromere	14	7.56e-02	1.65e-01	0.37800	0.308000	0.219000	4.58e-02	1.55e-01
Nucleosome assembly	14	7.56e-02	1.65e-01	0.37800	0.308000	0.219000	4.58e-02	1.55e-01
Organelle biogenesis and maintenance	224	7.58e-02	1.65e-01	0.08040	0.059500	-0.054100	1.27e-01	1.66e-01
Downstream signaling of activated FGFR2	17	7.65e-02	1.66e-01	0.31100	-0.008850	0.311000	9.50e-01	2.64e-02
Downstream signaling of activated FGFR3	17	7.74e-02	1.66e-01	0.32800	0.092900	0.315000	5.07e-01	2.47e-02
Misspliced GSK3beta mutants stabilize beta-catenin	14	7.76e-02	1.66e-01	0.37500	0.203000	0.316000	1.89e-01	4.10e-02
S33 mutants of beta-catenin aren't phosphorylated	14	7.76e-02	1.66e-01	0.37500	0.203000	0.316000	1.89e-01	4.10e-02
S37 mutants of beta-catenin aren't phosphorylated	14	7.76e-02	1.66e-01	0.37500	0.203000	0.316000	1.89e-01	4.10e-02
S45 mutants of beta-catenin aren't phosphorylated	14	7.76e-02	1.66e-01	0.37500	0.203000	0.316000	1.89e-01	4.10e-02
T41 mutants of beta-catenin aren't phosphorylated	14	7.76e-02	1.66e-01	0.37500	0.203000	0.316000	1.89e-01	4.10e-02
phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex	14	7.76e-02	1.66e-01	0.37500	0.203000	0.316000	1.89e-01	4.10e-02
Prolactin receptor signaling	10	7.78e-02	1.66e-01	0.44400	-0.247000	-0.369000	1.77e-01	4.31e-02
Activation of HOX genes during differentiation	50	7.79e-02	1.66e-01	0.20000	0.154000	0.128000	5.95e-02	1.19e-01
Activation of anterior HOX genes in hindbrain development during early embryogenesis	50	7.79e-02	1.66e-01	0.20000	0.154000	0.128000	5.95e-02	1.19e-01
Condensation of Prophase Chromosomes	11	7.79e-02	1.66e-01	0.41800	0.373000	0.190000	3.24e-02	2.75e-01
RNA Polymerase III Chain Elongation	17	7.81e-02	1.66e-01	0.30200	0.297000	-0.053800	3.38e-02	7.01e-01
Regulation of TP53 Activity through Methylation	14	7.81e-02	1.66e-01	0.35400	0.349000	0.060700	2.39e-02	6.94e-01
Transcriptional regulation of granulopoiesis	23	7.82e-02	1.66e-01	0.26600	-0.007540	0.266000	9.50e-01	2.71e-02
Inositol phosphate metabolism	39	7.84e-02	1.66e-01	0.19600	-0.187000	0.058200	4.32e-02	5.30e-01
Plasma lipoprotein assembly, remodeling, and clearance	39	7.90e-02	1.67e-01	0.21500	-0.208000	-0.053000	2.47e-02	5.67e-01
HSF1-dependent transactivation	30	8.04e-02	1.70e-01	0.24000	0.035400	0.237000	7.37e-01	2.48e-02
NOD1/2 Signaling Pathway	27	8.06e-02	1.70e-01	0.23100	-0.097900	0.209000	3.79e-01	6.07e-02
Synthesis of bile acids and bile salts	18	8.07e-02	1.70e-01	0.31800	-0.099000	-0.302000	4.67e-01	2.66e-02
MAP2K and MAPK activation	31	8.09e-02	1.70e-01	0.21700	-0.074100	0.204000	4.76e-01	4.93e-02
HDR through Homologous Recombination (HRR)	49	8.09e-02	1.70e-01	0.19900	0.170000	0.102000	3.95e-02	2.16e-01
Signaling by TGF-beta Receptor Complex	66	8.16e-02	1.70e-01	0.17300	0.119000	0.126000	9.64e-02	7.68e-02
Regulation of TNFR1 signaling	26	8.17e-02	1.70e-01	0.24400	-0.243000	0.030100	3.23e-02	7.90e-01
Prolonged ERK activation events	12	8.17e-02	1.70e-01	0.40100	0.220000	0.336000	1.88e-01	4.40e-02
The NLRP3 inflammasome	10	8.21e-02	1.71e-01	0.38700	-0.089300	0.376000	6.25e-01	3.93e-02
Interleukin-6 family signaling	16	8.26e-02	1.72e-01	0.29400	-0.246000	0.162000	8.88e-02	2.62e-01
APC/C-mediated degradation of cell cycle proteins	72	8.29e-02	1.72e-01	0.14200	0.135000	-0.046200	4.85e-02	4.98e-01
Regulation of mitotic cell cycle	72	8.29e-02	1.72e-01	0.14200	0.135000	-0.046200	4.85e-02	4.98e-01
PI-3K cascade:FGFR3	10	8.29e-02	1.72e-01	0.41300	0.065300	0.408000	7.21e-01	2.57e-02
SHC-mediated cascade:FGFR3	10	8.33e-02	1.72e-01	0.41500	0.081400	0.407000	6.56e-01	2.58e-02
Signaling by Retinoic Acid	29	8.34e-02	1.72e-01	0.26000	-0.177000	-0.190000	1.00e-01	7.64e-02
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	10	8.36e-02	1.72e-01	0.43300	0.198000	0.385000	2.78e-01	3.52e-02
TRAF6-mediated induction of TAK1 complex within TLR4 complex	10	8.36e-02	1.72e-01	0.43300	0.198000	0.385000	2.78e-01	3.52e-02
Formation of Senescence-Associated Heterochromatin Foci (SAHF)	10	8.38e-02	1.72e-01	0.42000	0.114000	0.404000	5.31e-01	2.68e-02
Intra-Golgi traffic	38	8.38e-02	1.72e-01	0.22500	0.128000	0.185000	1.72e-01	4.85e-02
Vasopressin regulates renal water homeostasis via Aquaporins	27	8.59e-02	1.76e-01	0.26700	-0.209000	-0.166000	6.04e-02	1.36e-01
KSRP (KHSRP) binds and destabilizes mRNA	16	8.72e-02	1.78e-01	0.33100	0.316000	0.100000	2.87e-02	4.89e-01
HDMs demethylate histones	19	8.75e-02	1.78e-01	0.31300	0.160000	0.269000	2.27e-01	4.21e-02
DNA Damage/Telomere Stress Induced Senescence	26	8.78e-02	1.79e-01	0.26900	0.225000	0.147000	4.72e-02	1.94e-01
GABA receptor activation	27	8.81e-02	1.79e-01	0.26300	-0.222000	-0.141000	4.57e-02	2.05e-01
NF-kB is activated and signals survival	10	8.82e-02	1.79e-01	0.37400	-0.142000	0.346000	4.38e-01	5.84e-02
G alpha (q) signalling events	78	8.85e-02	1.79e-01	0.14100	-0.141000	0.006140	3.16e-02	9.25e-01
Translation of structural proteins	25	8.87e-02	1.79e-01	0.23200	-0.194000	0.128000	9.41e-02	2.67e-01
Inhibition of DNA recombination at telomere	19	8.89e-02	1.79e-01	0.29000	0.290000	0.017100	2.89e-02	8.97e-01
Translesion synthesis by POLK	15	8.90e-02	1.79e-01	0.31900	0.318000	-0.023400	3.30e-02	8.75e-01
Transcriptional regulation of pluripotent stem cells	11	8.92e-02	1.79e-01	0.35700	-0.120000	0.337000	4.92e-01	5.32e-02
Class A/1 (Rhodopsin-like receptors)	39	9.04e-02	1.81e-01	0.18700	-0.088900	0.164000	3.37e-01	7.66e-02
MyD88 dependent cascade initiated on endosome	77	9.06e-02	1.81e-01	0.13500	-0.048000	0.126000	4.68e-01	5.66e-02
Toll Like Receptor 7/8 (TLR7/8) Cascade	77	9.06e-02	1.81e-01	0.13500	-0.048000	0.126000	4.68e-01	5.66e-02
Mitotic Telophase/Cytokinesis	10	9.08e-02	1.82e-01	0.41300	0.398000	0.111000	2.93e-02	5.45e-01
TNFR1-induced NFkappaB signaling pathway	21	9.15e-02	1.82e-01	0.25500	-0.233000	0.105000	6.51e-02	4.06e-01
Erythropoietin activates RAS	11	9.17e-02	1.82e-01	0.38100	0.037000	0.379000	8.32e-01	2.93e-02
Transcriptional regulation of white adipocyte differentiation	71	9.17e-02	1.82e-01	0.15800	0.147000	0.058300	3.29e-02	3.97e-01
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	31	9.17e-02	1.82e-01	0.22800	0.026200	0.227000	8.01e-01	2.91e-02
G alpha (z) signalling events	29	9.33e-02	1.85e-01	0.23400	-0.233000	-0.020300	3.01e-02	8.50e-01
InlB-mediated entry of Listeria monocytogenes into host cell	11	9.39e-02	1.86e-01	0.39800	0.151000	0.369000	3.85e-01	3.43e-02
O-glycosylation of TSR domain-containing proteins	25	9.41e-02	1.86e-01	0.22800	-0.144000	0.177000	2.12e-01	1.26e-01
Signaling by FGFR4	29	9.41e-02	1.86e-01	0.23700	0.040300	0.233000	7.07e-01	2.97e-02
Interleukin-17 signaling	62	9.45e-02	1.86e-01	0.14500	-0.102000	0.103000	1.64e-01	1.63e-01
RNA Polymerase III Transcription Initiation From Type 1 Promoter	26	9.49e-02	1.87e-01	0.24900	0.246000	0.040100	3.00e-02	7.24e-01
Polymerase switching on the C-strand of the telomere	22	9.56e-02	1.88e-01	0.28400	0.252000	0.132000	4.11e-02	2.83e-01
Formation of Incision Complex in GG-NER	39	9.59e-02	1.88e-01	0.18600	0.173000	-0.068700	6.14e-02	4.58e-01
Caspase-mediated cleavage of cytoskeletal proteins	11	9.61e-02	1.88e-01	0.34200	-0.257000	0.225000	1.39e-01	1.96e-01
APC/C:Cdc20 mediated degradation of mitotic proteins	63	9.98e-02	1.95e-01	0.14500	0.134000	-0.055900	6.60e-02	4.43e-01
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins	63	9.98e-02	1.95e-01	0.14500	0.134000	-0.055900	6.60e-02	4.43e-01
FCERI mediated Ca+2 mobilization	18	1.00e-01	1.95e-01	0.26700	-0.223000	0.146000	1.01e-01	2.84e-01
Negative regulation of FGFR4 signaling	19	1.01e-01	1.95e-01	0.27800	-0.010300	0.278000	9.38e-01	3.62e-02
RNA Polymerase I Transcription Termination	25	1.01e-01	1.95e-01	0.25300	0.248000	0.052600	3.22e-02	6.49e-01
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	76	1.01e-01	1.96e-01	0.13200	-0.051300	0.122000	4.40e-01	6.75e-02
Transport of bile salts and organic acids, metal ions and amine compounds	32	1.02e-01	1.97e-01	0.20000	-0.099100	0.174000	3.32e-01	8.83e-02
The role of Nef in HIV-1 replication and disease pathogenesis	19	1.02e-01	1.98e-01	0.26300	-0.096200	0.245000	4.68e-01	6.47e-02
p75NTR recruits signalling complexes	10	1.03e-01	1.98e-01	0.40300	0.111000	0.387000	5.42e-01	3.40e-02
Synaptic adhesion-like molecules	12	1.03e-01	1.99e-01	0.34500	-0.344000	0.027400	3.92e-02	8.70e-01
Neurotransmitter release cycle	22	1.04e-01	2.00e-01	0.25900	0.005280	0.259000	9.66e-01	3.57e-02
MHC class II antigen presentation	71	1.04e-01	2.00e-01	0.15800	0.090400	0.129000	1.89e-01	6.04e-02
Anti-inflammatory response favouring Leishmania parasite infection	56	1.05e-01	2.01e-01	0.15800	-0.156000	0.022800	4.35e-02	7.69e-01
Leishmania parasite growth and survival	56	1.05e-01	2.01e-01	0.15800	-0.156000	0.022800	4.35e-02	7.69e-01
IKK complex recruitment mediated by RIP1	14	1.09e-01	2.08e-01	0.34200	0.130000	0.316000	4.00e-01	4.05e-02
RNA Polymerase III Abortive And Retractive Initiation	39	1.09e-01	2.08e-01	0.20000	0.195000	0.045300	3.56e-02	6.25e-01
RNA Polymerase III Transcription	39	1.09e-01	2.08e-01	0.20000	0.195000	0.045300	3.56e-02	6.25e-01
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon	10	1.11e-01	2.11e-01	0.39600	0.109000	0.381000	5.49e-01	3.71e-02
Binding and Uptake of Ligands by Scavenger Receptors	23	1.11e-01	2.11e-01	0.22900	-0.152000	0.171000	2.06e-01	1.55e-01
Translesion synthesis by POLI	15	1.12e-01	2.12e-01	0.30900	0.309000	0.009320	3.84e-02	9.50e-01
Formation of the beta-catenin:TCF transactivating complex	28	1.12e-01	2.12e-01	0.24800	0.158000	0.190000	1.47e-01	8.15e-02
AKT phosphorylates targets in the nucleus	10	1.12e-01	2.12e-01	0.38300	-0.381000	-0.039500	3.70e-02	8.29e-01
Translation of Replicase and Assembly of the Replication Transcription Complex	11	1.12e-01	2.12e-01	0.33100	0.238000	-0.229000	1.71e-01	1.88e-01
SUMOylation of intracellular receptors	23	1.12e-01	2.12e-01	0.26400	-0.247000	-0.091700	4.02e-02	4.47e-01
Signaling by TGFB family members	86	1.14e-01	2.14e-01	0.13600	0.047000	0.128000	4.52e-01	4.06e-02
Cargo recognition for clathrin-mediated endocytosis	73	1.14e-01	2.14e-01	0.15300	0.116000	0.101000	8.84e-02	1.38e-01
activated TAK1 mediates p38 MAPK activation	17	1.15e-01	2.15e-01	0.26500	-0.171000	0.202000	2.23e-01	1.48e-01
Anchoring of the basal body to the plasma membrane	83	1.15e-01	2.15e-01	0.14200	0.121000	0.073600	5.66e-02	2.47e-01
Negative regulation of FGFR1 signaling	19	1.15e-01	2.15e-01	0.27600	0.027500	0.275000	8.36e-01	3.81e-02
Switching of origins to a post-replicative state	79	1.16e-01	2.16e-01	0.13400	0.134000	0.004230	3.98e-02	9.48e-01
DNA Replication Pre-Initiation	70	1.16e-01	2.17e-01	0.15100	0.139000	0.058600	4.40e-02	3.97e-01
Interleukin-20 family signaling	12	1.17e-01	2.18e-01	0.32600	-0.315000	0.084300	5.90e-02	6.13e-01
Regulation of TP53 Degradation	32	1.17e-01	2.18e-01	0.21900	0.210000	0.063000	3.99e-02	5.38e-01
G alpha (s) signalling events	51	1.18e-01	2.18e-01	0.17700	-0.161000	-0.073100	4.66e-02	3.67e-01
Activation of GABAB receptors	25	1.19e-01	2.18e-01	0.25700	-0.213000	-0.143000	6.54e-02	2.15e-01
GABA B receptor activation	25	1.19e-01	2.18e-01	0.25700	-0.213000	-0.143000	6.54e-02	2.15e-01
AMER1 mutants destabilize the destruction complex	13	1.19e-01	2.18e-01	0.35500	0.189000	0.300000	2.38e-01	6.10e-02
APC truncation mutants have impaired AXIN binding	13	1.19e-01	2.18e-01	0.35500	0.189000	0.300000	2.38e-01	6.10e-02
AXIN missense mutants destabilize the destruction complex	13	1.19e-01	2.18e-01	0.35500	0.189000	0.300000	2.38e-01	6.10e-02
AXIN mutants destabilize the destruction complex, activating WNT signaling	13	1.19e-01	2.18e-01	0.35500	0.189000	0.300000	2.38e-01	6.10e-02
Truncations of AMER1 destabilize the destruction complex	13	1.19e-01	2.18e-01	0.35500	0.189000	0.300000	2.38e-01	6.10e-02
truncated APC mutants destabilize the destruction complex	13	1.19e-01	2.18e-01	0.35500	0.189000	0.300000	2.38e-01	6.10e-02
Synthesis of PIPs at the plasma membrane	44	1.20e-01	2.18e-01	0.19200	0.095500	0.167000	2.73e-01	5.58e-02
Regulation of PLK1 Activity at G2/M Transition	74	1.20e-01	2.18e-01	0.14900	0.125000	0.080600	6.24e-02	2.31e-01
MyD88:MAL(TIRAP) cascade initiated on plasma membrane	81	1.20e-01	2.18e-01	0.12200	-0.054900	0.109000	3.94e-01	9.03e-02
Toll Like Receptor 2 (TLR2) Cascade	81	1.20e-01	2.18e-01	0.12200	-0.054900	0.109000	3.94e-01	9.03e-02
Toll Like Receptor TLR1:TLR2 Cascade	81	1.20e-01	2.18e-01	0.12200	-0.054900	0.109000	3.94e-01	9.03e-02
Toll Like Receptor TLR6:TLR2 Cascade	81	1.20e-01	2.18e-01	0.12200	-0.054900	0.109000	3.94e-01	9.03e-02
Frs2-mediated activation	10	1.21e-01	2.19e-01	0.39300	0.138000	0.368000	4.49e-01	4.38e-02
Circadian Clock	63	1.22e-01	2.20e-01	0.13600	-0.092300	0.099800	2.06e-01	1.71e-01
TBC/RABGAPs	39	1.22e-01	2.20e-01	0.19700	0.056800	0.189000	5.40e-01	4.17e-02
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	36	1.22e-01	2.20e-01	0.20500	0.060100	0.196000	5.33e-01	4.19e-02
Signaling by ERBB2	37	1.25e-01	2.26e-01	0.18000	-0.070900	0.165000	4.56e-01	8.25e-02
Regulation of TP53 Expression and Degradation	33	1.25e-01	2.26e-01	0.20800	0.205000	0.036000	4.16e-02	7.21e-01
MyD88 cascade initiated on plasma membrane	75	1.26e-01	2.26e-01	0.12400	-0.067600	0.104000	3.12e-01	1.19e-01
Toll Like Receptor 10 (TLR10) Cascade	75	1.26e-01	2.26e-01	0.12400	-0.067600	0.104000	3.12e-01	1.19e-01
Toll Like Receptor 5 (TLR5) Cascade	75	1.26e-01	2.26e-01	0.12400	-0.067600	0.104000	3.12e-01	1.19e-01
ER to Golgi Anterograde Transport	114	1.26e-01	2.26e-01	0.12000	0.090800	0.078300	9.51e-02	1.50e-01
Activation of BH3-only proteins	25	1.27e-01	2.26e-01	0.21700	-0.090900	0.197000	4.32e-01	8.80e-02
Activation of BAD and translocation to mitochondria	13	1.27e-01	2.27e-01	0.29500	-0.221000	0.196000	1.69e-01	2.21e-01
Interferon alpha/beta signaling	36	1.27e-01	2.27e-01	0.19100	-0.008140	0.191000	9.33e-01	4.75e-02
Insulin receptor signalling cascade	32	1.30e-01	2.31e-01	0.21000	0.037300	0.207000	7.15e-01	4.32e-02
ABC-family proteins mediated transport	76	1.31e-01	2.34e-01	0.12400	0.050800	-0.113000	4.44e-01	8.94e-02
Defective B3GALTL causes Peters-plus syndrome (PpS)	24	1.33e-01	2.36e-01	0.21500	-0.143000	0.161000	2.26e-01	1.72e-01
Scavenging by Class A Receptors	13	1.36e-01	2.41e-01	0.29000	-0.196000	0.215000	2.22e-01	1.80e-01
Chaperone Mediated Autophagy	14	1.37e-01	2.42e-01	0.29400	-0.055000	0.288000	7.22e-01	6.17e-02
Regulation of IFNG signaling	13	1.38e-01	2.44e-01	0.33700	0.136000	0.308000	3.98e-01	5.44e-02
Signaling by NOTCH	149	1.38e-01	2.44e-01	0.08600	-0.063900	0.057600	1.79e-01	2.27e-01
SHC1 events in ERBB2 signaling	15	1.39e-01	2.45e-01	0.27000	-0.163000	0.215000	2.75e-01	1.50e-01
MAP kinase activation	59	1.39e-01	2.45e-01	0.13600	-0.091500	0.101000	2.25e-01	1.82e-01
Interleukin-2 family signaling	22	1.43e-01	2.51e-01	0.22100	-0.168000	0.143000	1.73e-01	2.44e-01
RNA Polymerase I Promoter Clearance	43	1.43e-01	2.51e-01	0.18600	0.161000	0.093200	6.78e-02	2.91e-01
Downregulation of SMAD2/3:SMAD4 transcriptional activity	19	1.44e-01	2.53e-01	0.28200	0.171000	0.224000	1.97e-01	9.08e-02
Regulation of IFNA signaling	12	1.45e-01	2.54e-01	0.31600	-0.037800	0.314000	8.21e-01	6.00e-02
Signaling by Hippo	18	1.47e-01	2.57e-01	0.28000	0.106000	0.259000	4.35e-01	5.69e-02
Extra-nuclear estrogen signaling	53	1.48e-01	2.57e-01	0.16000	0.041600	0.155000	6.01e-01	5.16e-02
Disassembly of the destruction complex and recruitment of AXIN to the membrane	25	1.48e-01	2.57e-01	0.23200	0.056500	0.225000	6.25e-01	5.12e-02
IGF1R signaling cascade	30	1.48e-01	2.57e-01	0.20800	0.027800	0.206000	7.92e-01	5.09e-02
Signaling by Insulin receptor	48	1.48e-01	2.57e-01	0.16800	0.041700	0.163000	6.18e-01	5.15e-02
TCR signaling	79	1.48e-01	2.57e-01	0.13500	0.056900	0.122000	3.83e-01	6.08e-02
Caspase activation via Death Receptors in the presence of ligand	11	1.49e-01	2.58e-01	0.30900	-0.239000	0.196000	1.70e-01	2.61e-01
Regulation of TP53 Activity through Acetylation	28	1.50e-01	2.60e-01	0.23100	0.162000	0.165000	1.39e-01	1.32e-01
Signaling by FGFR2 in disease	28	1.51e-01	2.61e-01	0.22800	0.123000	0.192000	2.60e-01	7.85e-02
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	10	1.51e-01	2.61e-01	0.34100	0.337000	-0.050100	6.49e-02	7.84e-01
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	63	1.53e-01	2.63e-01	0.13000	0.117000	-0.057200	1.08e-01	4.33e-01
Toll Like Receptor 9 (TLR9) Cascade	80	1.53e-01	2.63e-01	0.12000	-0.023600	0.117000	7.16e-01	7.03e-02
Translesion synthesis by REV1	14	1.55e-01	2.66e-01	0.29100	0.291000	-0.014400	5.96e-02	9.26e-01
Assembly and cell surface presentation of NMDA receptors	13	1.55e-01	2.66e-01	0.29100	-0.280000	0.080500	8.08e-02	6.16e-01
Signaling by PDGFR in disease	17	1.56e-01	2.67e-01	0.28200	0.092700	0.266000	5.08e-01	5.74e-02
Apoptotic cleavage of cellular proteins	27	1.56e-01	2.68e-01	0.19500	-0.126000	0.148000	2.56e-01	1.84e-01
APC/C:Cdc20 mediated degradation of Securin	59	1.57e-01	2.69e-01	0.13200	0.107000	-0.076800	1.54e-01	3.08e-01
Phase II - Conjugation of compounds	46	1.58e-01	2.70e-01	0.17300	-0.067500	-0.159000	4.29e-01	6.24e-02
Resolution of AP sites via the multiple-nucleotide patch replacement pathway	24	1.59e-01	2.70e-01	0.24300	0.206000	0.129000	8.08e-02	2.76e-01
Costimulation by the CD28 family	39	1.59e-01	2.70e-01	0.17300	-0.009620	0.173000	9.17e-01	6.20e-02
Zinc transporters	11	1.59e-01	2.70e-01	0.35900	0.304000	0.190000	8.12e-02	2.74e-01
Synthesis of substrates in N-glycan biosythesis	52	1.60e-01	2.71e-01	0.14000	-0.107000	0.089600	1.82e-01	2.64e-01
DARPP-32 events	21	1.63e-01	2.77e-01	0.26000	-0.202000	-0.163000	1.09e-01	1.96e-01
Eukaryotic Translation Elongation	56	1.64e-01	2.78e-01	0.15800	-0.088300	-0.131000	2.54e-01	8.95e-02
Interleukin-1 signaling	84	1.64e-01	2.78e-01	0.12500	0.036700	0.119000	5.62e-01	5.95e-02
Bile acid and bile salt metabolism	20	1.65e-01	2.78e-01	0.26100	-0.116000	-0.233000	3.69e-01	7.08e-02
FRS-mediated FGFR4 signaling	12	1.65e-01	2.78e-01	0.30200	-0.056500	0.296000	7.35e-01	7.54e-02
Processing of Intronless Pre-mRNAs	17	1.66e-01	2.78e-01	0.28800	0.223000	0.182000	1.12e-01	1.94e-01
Leading Strand Synthesis	14	1.66e-01	2.78e-01	0.31800	0.227000	0.222000	1.41e-01	1.51e-01
Polymerase switching	14	1.66e-01	2.78e-01	0.31800	0.227000	0.222000	1.41e-01	1.51e-01
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)	13	1.66e-01	2.79e-01	0.28100	0.112000	-0.258000	4.84e-01	1.08e-01
Uptake and actions of bacterial toxins	21	1.66e-01	2.79e-01	0.21800	-0.127000	0.177000	3.15e-01	1.61e-01
ERK/MAPK targets	22	1.71e-01	2.87e-01	0.24100	-0.229000	-0.076700	6.37e-02	5.34e-01
APC-Cdc20 mediated degradation of Nek2A	21	1.73e-01	2.89e-01	0.21700	0.192000	-0.102000	1.29e-01	4.18e-01
HDR through Single Strand Annealing (SSA)	30	1.74e-01	2.90e-01	0.19800	0.197000	0.020000	6.21e-02	8.50e-01
Transport of vitamins, nucleosides, and related molecules	24	1.75e-01	2.90e-01	0.21000	-0.205000	0.042200	8.17e-02	7.20e-01
Antigen Presentation: Folding, assembly and peptide loading of class I MHC	17	1.75e-01	2.90e-01	0.28200	0.229000	0.166000	1.03e-01	2.37e-01
AURKA Activation by TPX2	62	1.75e-01	2.90e-01	0.14800	0.121000	0.085900	1.01e-01	2.43e-01
Meiotic synapsis	22	1.75e-01	2.90e-01	0.24100	0.225000	0.087200	6.79e-02	4.79e-01
Lysosome Vesicle Biogenesis	27	1.75e-01	2.91e-01	0.22200	0.108000	0.194000	3.32e-01	8.18e-02
ER Quality Control Compartment (ERQC)	18	1.77e-01	2.92e-01	0.26700	0.101000	0.247000	4.58e-01	6.99e-02
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint	62	1.78e-01	2.93e-01	0.12800	0.121000	-0.042000	1.01e-01	5.68e-01
Cdc20:Phospho-APC/C mediated degradation of Cyclin A	62	1.78e-01	2.93e-01	0.12800	0.121000	-0.042000	1.01e-01	5.68e-01
TP53 Regulates Metabolic Genes	79	1.78e-01	2.93e-01	0.13000	-0.068700	-0.110000	2.92e-01	9.06e-02
PI-3K cascade:FGFR4	10	1.79e-01	2.94e-01	0.31600	-0.105000	0.299000	5.65e-01	1.02e-01
VEGFR2 mediated vascular permeability	23	1.80e-01	2.96e-01	0.20700	-0.078900	0.192000	5.13e-01	1.12e-01
RUNX2 regulates bone development	26	1.82e-01	2.98e-01	0.20300	-0.019000	0.202000	8.67e-01	7.51e-02
RNA Polymerase I Transcription	44	1.82e-01	2.98e-01	0.17300	0.144000	0.095600	9.77e-02	2.73e-01
FGFR2 mutant receptor activation	18	1.84e-01	3.01e-01	0.27100	0.165000	0.215000	2.25e-01	1.15e-01
CREB1 phosphorylation through the activation of Adenylate Cyclase	10	1.85e-01	3.02e-01	0.31900	-0.312000	0.066500	8.75e-02	7.16e-01
Signaling by Leptin	10	1.86e-01	3.04e-01	0.32200	-0.320000	0.042600	8.02e-02	8.15e-01
CDK-mediated phosphorylation and removal of Cdc6	63	1.87e-01	3.04e-01	0.12700	0.125000	-0.024800	8.68e-02	7.34e-01
Downstream signaling of activated FGFR4	17	1.88e-01	3.07e-01	0.25100	-0.007380	0.251000	9.58e-01	7.37e-02
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol	10	1.92e-01	3.12e-01	0.35000	-0.141000	-0.321000	4.41e-01	7.90e-02
TCF dependent signaling in response to WNT	134	1.92e-01	3.12e-01	0.09530	0.032400	0.089700	5.19e-01	7.41e-02
Mismatch Repair	14	1.92e-01	3.12e-01	0.25400	0.169000	-0.190000	2.74e-01	2.18e-01
E2F mediated regulation of DNA replication	19	1.93e-01	3.12e-01	0.24300	0.240000	0.035400	6.97e-02	7.89e-01
CLEC7A (Dectin-1) induces NFAT activation	10	1.93e-01	3.12e-01	0.33100	-0.330000	-0.027800	7.09e-02	8.79e-01
SHC-mediated cascade:FGFR4	10	1.93e-01	3.13e-01	0.31100	-0.089000	0.298000	6.26e-01	1.03e-01
Fanconi Anemia Pathway	25	1.95e-01	3.15e-01	0.19800	0.193000	-0.044800	9.50e-02	6.99e-01
DNA Damage Bypass	43	1.96e-01	3.16e-01	0.16800	0.155000	0.063900	7.92e-02	4.69e-01
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	20	1.97e-01	3.17e-01	0.25200	-0.168000	-0.188000	1.93e-01	1.46e-01
Signaling by BMP	23	1.97e-01	3.17e-01	0.20600	-0.046600	0.200000	6.99e-01	9.62e-02
DNA Damage Recognition in GG-NER	34	1.99e-01	3.19e-01	0.17100	0.170000	-0.023400	8.69e-02	8.13e-01
Constitutive Signaling by AKT1 E17K in Cancer	26	1.99e-01	3.19e-01	0.18900	-0.177000	0.068400	1.19e-01	5.47e-01
ATF6 (ATF6-alpha) activates chaperones	12	1.99e-01	3.19e-01	0.31300	0.106000	0.294000	5.23e-01	7.76e-02
Signaling by WNT	202	2.01e-01	3.22e-01	0.07490	0.014600	0.073400	7.22e-01	7.34e-02
Other interleukin signaling	13	2.03e-01	3.25e-01	0.26200	-0.132000	0.226000	4.10e-01	1.58e-01
Regulation of lipid metabolism by PPARalpha	103	2.06e-01	3.28e-01	0.09670	0.094700	-0.019600	9.76e-02	7.31e-01
Constitutive Signaling by Overexpressed ERBB2	10	2.06e-01	3.29e-01	0.33600	0.092200	0.323000	6.14e-01	7.74e-02
FRS-mediated FGFR1 signaling	12	2.07e-01	3.29e-01	0.29200	0.003190	0.292000	9.85e-01	8.00e-02
Regulation of cholesterol biosynthesis by SREBP (SREBF)	53	2.07e-01	3.29e-01	0.12800	-0.089500	0.091500	2.61e-01	2.50e-01
Dual Incision in GG-NER	38	2.08e-01	3.30e-01	0.16000	0.159000	-0.021500	9.10e-02	8.19e-01
Purine ribonucleoside monophosphate biosynthesis	12	2.09e-01	3.32e-01	0.28600	0.024000	-0.285000	8.86e-01	8.74e-02
WNT5A-dependent internalization of FZD2, FZD5 and ROR2	13	2.11e-01	3.34e-01	0.28000	0.008550	0.280000	9.57e-01	8.09e-02
Membrane binding and targetting of GAG proteins	10	2.12e-01	3.34e-01	0.31100	-0.032400	0.309000	8.59e-01	9.04e-02
Synthesis And Processing Of GAG, GAGPOL Polyproteins	10	2.12e-01	3.34e-01	0.31100	-0.032400	0.309000	8.59e-01	9.04e-02
Inactivation of APC/C via direct inhibition of the APC/C complex	19	2.12e-01	3.34e-01	0.21300	0.171000	-0.126000	1.96e-01	3.43e-01
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components	19	2.12e-01	3.34e-01	0.21300	0.171000	-0.126000	1.96e-01	3.43e-01
CDT1 association with the CDC6:ORC:origin complex	48	2.13e-01	3.34e-01	0.13500	0.120000	-0.062900	1.52e-01	4.51e-01
Transcriptional Regulation by MECP2	42	2.20e-01	3.45e-01	0.15200	-0.152000	0.005810	8.90e-02	9.48e-01
Regulation of APC/C activators between G1/S and early anaphase	67	2.20e-01	3.45e-01	0.11500	0.108000	-0.038500	1.26e-01	5.86e-01
Vitamin B5 (pantothenate) metabolism	15	2.21e-01	3.47e-01	0.23700	0.120000	-0.205000	4.21e-01	1.70e-01
Regulation of insulin secretion	47	2.22e-01	3.47e-01	0.13800	-0.132000	0.039600	1.19e-01	6.39e-01
Selective autophagy	51	2.22e-01	3.47e-01	0.13300	0.033000	-0.129000	6.84e-01	1.12e-01
IRS-related events triggered by IGF1R	29	2.23e-01	3.47e-01	0.18300	0.000983	0.183000	9.93e-01	8.77e-02
Plasma lipoprotein remodeling	11	2.23e-01	3.48e-01	0.32200	-0.282000	-0.155000	1.05e-01	3.74e-01
Lagging Strand Synthesis	20	2.24e-01	3.48e-01	0.23300	0.221000	0.072300	8.72e-02	5.76e-01
Activated NTRK2 signals through FRS2 and FRS3	10	2.25e-01	3.49e-01	0.31900	0.047400	0.316000	7.95e-01	8.41e-02
CTLA4 inhibitory signaling	17	2.29e-01	3.55e-01	0.23200	-0.028100	0.230000	8.41e-01	1.00e-01
Apoptotic execution phase	35	2.29e-01	3.56e-01	0.15800	-0.039600	0.153000	6.85e-01	1.17e-01
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA	15	2.31e-01	3.58e-01	0.25500	0.254000	0.019100	8.85e-02	8.98e-01
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	75	2.33e-01	3.60e-01	0.10400	0.065700	-0.080400	3.26e-01	2.30e-01
Nonsense-Mediated Decay (NMD)	75	2.33e-01	3.60e-01	0.10400	0.065700	-0.080400	3.26e-01	2.30e-01
Signaling by FGFR3 fusions in cancer	10	2.34e-01	3.61e-01	0.33600	0.192000	0.275000	2.93e-01	1.32e-01
Signaling by FGFR3 in disease	14	2.36e-01	3.63e-01	0.26700	0.049600	0.262000	7.48e-01	8.91e-02
Signaling by FGFR3 point mutants in cancer	14	2.36e-01	3.63e-01	0.26700	0.049600	0.262000	7.48e-01	8.91e-02
Signaling by FGFR in disease	47	2.36e-01	3.63e-01	0.15400	0.078800	0.132000	3.50e-01	1.18e-01
Disorders of transmembrane transporters	107	2.38e-01	3.65e-01	0.10300	0.067800	0.077600	2.27e-01	1.67e-01
DAP12 interactions	15	2.40e-01	3.67e-01	0.25300	0.026200	0.251000	8.60e-01	9.18e-02
DAP12 signaling	15	2.40e-01	3.67e-01	0.25300	0.026200	0.251000	8.60e-01	9.18e-02
Carboxyterminal post-translational modifications of tubulin	21	2.44e-01	3.73e-01	0.19300	-0.153000	0.117000	2.24e-01	3.55e-01
DCC mediated attractive signaling	13	2.45e-01	3.73e-01	0.24400	-0.157000	0.187000	3.28e-01	2.43e-01
HSF1 activation	22	2.45e-01	3.73e-01	0.22300	0.179000	0.134000	1.47e-01	2.77e-01
Interleukin-15 signaling	11	2.45e-01	3.73e-01	0.27000	-0.247000	0.109000	1.56e-01	5.30e-01
Nucleobase biosynthesis	15	2.45e-01	3.73e-01	0.24100	0.031700	-0.239000	8.32e-01	1.10e-01
Cargo concentration in the ER	21	2.45e-01	3.73e-01	0.22000	0.209000	0.067900	9.73e-02	5.90e-01
Metal ion SLC transporters	17	2.46e-01	3.74e-01	0.24700	0.096100	0.228000	4.93e-01	1.04e-01
PI-3K cascade:FGFR1	10	2.47e-01	3.74e-01	0.29500	-0.033500	0.293000	8.54e-01	1.09e-01
PPARA activates gene expression	101	2.48e-01	3.76e-01	0.09070	0.087100	-0.025300	1.31e-01	6.62e-01
Interleukin-12 family signaling	36	2.49e-01	3.77e-01	0.15800	0.000371	0.158000	9.97e-01	1.01e-01
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1	16	2.50e-01	3.78e-01	0.22500	-0.074700	0.212000	6.05e-01	1.43e-01
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)	16	2.51e-01	3.78e-01	0.24900	0.239000	0.070700	9.86e-02	6.24e-01
Degradation of beta-catenin by the destruction complex	72	2.51e-01	3.78e-01	0.12100	0.108000	0.054800	1.15e-01	4.23e-01
Metabolism of folate and pterines	13	2.51e-01	3.79e-01	0.26600	-0.265000	-0.021000	9.82e-02	8.96e-01
RIP-mediated NFkB activation via ZBP1	14	2.53e-01	3.80e-01	0.26500	0.076300	0.254000	6.21e-01	1.00e-01
Spry regulation of FGF signaling	14	2.53e-01	3.80e-01	0.25600	0.024900	0.255000	8.72e-01	9.85e-02
Downstream TCR signaling	67	2.53e-01	3.80e-01	0.12700	0.086600	0.093100	2.21e-01	1.88e-01
Loss of Nlp from mitotic centrosomes	60	2.57e-01	3.84e-01	0.13400	0.099900	0.088700	1.81e-01	2.35e-01
Loss of proteins required for interphase microtubule organization from the centrosome	60	2.57e-01	3.84e-01	0.13400	0.099900	0.088700	1.81e-01	2.35e-01
SHC-mediated cascade:FGFR1	10	2.57e-01	3.84e-01	0.29300	-0.017400	0.293000	9.24e-01	1.09e-01
Nicotinate metabolism	20	2.57e-01	3.84e-01	0.22900	-0.128000	-0.190000	3.22e-01	1.41e-01
Viral mRNA Translation	53	2.57e-01	3.84e-01	0.13800	-0.055000	-0.127000	4.89e-01	1.11e-01
Transcription of E2F targets under negative control by DREAM complex	17	2.58e-01	3.84e-01	0.23300	0.231000	0.034700	9.99e-02	8.04e-01
DNA strand elongation	30	2.60e-01	3.87e-01	0.18800	0.136000	0.130000	1.98e-01	2.18e-01
Platelet sensitization by LDL	13	2.63e-01	3.90e-01	0.27700	0.118000	0.251000	4.61e-01	1.17e-01
NOTCH1 Intracellular Domain Regulates Transcription	42	2.64e-01	3.92e-01	0.13600	-0.042800	0.129000	6.31e-01	1.47e-01
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	30	2.65e-01	3.92e-01	0.18400	0.161000	0.088700	1.28e-01	4.01e-01
Glutamate binding, activation of AMPA receptors and synaptic plasticity	19	2.65e-01	3.92e-01	0.20100	-0.189000	0.068800	1.53e-01	6.04e-01
Trafficking of AMPA receptors	19	2.65e-01	3.92e-01	0.20100	-0.189000	0.068800	1.53e-01	6.04e-01
Regulation of RUNX1 Expression and Activity	17	2.67e-01	3.95e-01	0.23500	0.063400	0.226000	6.51e-01	1.06e-01
PCNA-Dependent Long Patch Base Excision Repair	21	2.68e-01	3.95e-01	0.21900	0.189000	0.111000	1.34e-01	3.80e-01
Regulation of localization of FOXO transcription factors	11	2.68e-01	3.95e-01	0.25800	-0.140000	0.217000	4.23e-01	2.12e-01
Signaling by NTRK3 (TRKC)	16	2.68e-01	3.95e-01	0.21300	-0.155000	0.145000	2.82e-01	3.15e-01
Cell recruitment (pro-inflammatory response)	12	2.70e-01	3.96e-01	0.26200	-0.020900	0.261000	9.00e-01	1.17e-01
Purinergic signaling in leishmaniasis infection	12	2.70e-01	3.96e-01	0.26200	-0.020900	0.261000	9.00e-01	1.17e-01
PKMTs methylate histone lysines	37	2.71e-01	3.97e-01	0.16000	0.152000	0.047400	1.09e-01	6.18e-01
Transcriptional regulation by RUNX3	86	2.71e-01	3.97e-01	0.10000	0.005620	0.100000	9.28e-01	1.09e-01
Signaling by NOTCH1	63	2.73e-01	4.00e-01	0.10900	-0.044900	0.098900	5.38e-01	1.75e-01
EGFR downregulation	22	2.74e-01	4.00e-01	0.21500	0.154000	0.151000	2.12e-01	2.21e-01
RNA Polymerase I Transcription Initiation	40	2.77e-01	4.05e-01	0.15300	0.144000	0.052300	1.16e-01	5.67e-01
Recycling pathway of L1	23	2.81e-01	4.09e-01	0.18200	-0.041700	0.177000	7.29e-01	1.42e-01
Signal transduction by L1	20	2.81e-01	4.09e-01	0.18700	-0.130000	0.134000	3.13e-01	3.01e-01
FOXO-mediated transcription of cell cycle genes	16	2.83e-01	4.12e-01	0.20900	-0.163000	0.130000	2.58e-01	3.69e-01
Thrombin signalling through proteinase activated receptors (PARs)	20	2.84e-01	4.13e-01	0.19300	-0.049800	0.187000	7.00e-01	1.48e-01
Signaling by PDGFRA extracellular domain mutants	11	2.85e-01	4.13e-01	0.28800	0.098600	0.271000	5.72e-01	1.20e-01
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants	11	2.85e-01	4.13e-01	0.28800	0.098600	0.271000	5.72e-01	1.20e-01
Post-translational modification: synthesis of GPI-anchored proteins	36	2.87e-01	4.15e-01	0.14800	0.013500	-0.147000	8.89e-01	1.27e-01
Telomere C-strand synthesis initiation	11	2.93e-01	4.23e-01	0.26300	0.261000	-0.032600	1.34e-01	8.51e-01
ADORA2B mediated anti-inflammatory cytokines production	38	2.95e-01	4.25e-01	0.15600	-0.139000	-0.070900	1.39e-01	4.50e-01
mRNA decay by 3' to 5' exoribonuclease	15	2.95e-01	4.25e-01	0.23300	0.232000	0.020100	1.20e-01	8.93e-01
Acyl chain remodelling of PS	10	2.96e-01	4.26e-01	0.30900	0.217000	0.220000	2.34e-01	2.28e-01
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10	10	2.96e-01	4.26e-01	0.26500	-0.245000	0.099800	1.80e-01	5.85e-01
IRS-mediated signalling	27	2.97e-01	4.27e-01	0.17600	0.031000	0.173000	7.81e-01	1.19e-01
PIWI-interacting RNA (piRNA) biogenesis	13	2.99e-01	4.30e-01	0.24600	0.246000	0.005300	1.25e-01	9.74e-01
TICAM1, RIP1-mediated IKK complex recruitment	14	3.00e-01	4.30e-01	0.25400	0.112000	0.229000	4.70e-01	1.39e-01
Cargo trafficking to the periciliary membrane	42	3.01e-01	4.30e-01	0.14300	0.137000	0.039900	1.23e-01	6.55e-01
Signaling by NTRK2 (TRKB)	21	3.01e-01	4.30e-01	0.19400	0.009540	0.194000	9.40e-01	1.24e-01
Regulation of expression of SLITs and ROBOs	114	3.03e-01	4.32e-01	0.07850	0.025900	-0.074100	6.33e-01	1.73e-01
SRP-dependent cotranslational protein targeting to membrane	74	3.03e-01	4.32e-01	0.09900	0.096800	-0.020500	1.51e-01	7.60e-01
Synthesis of PIPs at the late endosome membrane	10	3.03e-01	4.32e-01	0.30300	0.257000	0.159000	1.59e-01	3.83e-01
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters	15	3.03e-01	4.32e-01	0.21000	-0.125000	0.169000	4.03e-01	2.59e-01
Activation of AMPK downstream of NMDARs	10	3.04e-01	4.32e-01	0.28400	-0.282000	-0.039000	1.23e-01	8.31e-01
Peptide chain elongation	53	3.06e-01	4.35e-01	0.13100	-0.068600	-0.112000	3.88e-01	1.60e-01
FOXO-mediated transcription	51	3.07e-01	4.36e-01	0.12100	-0.121000	0.007350	1.35e-01	9.28e-01
Platelet homeostasis	51	3.08e-01	4.37e-01	0.12200	-0.122000	0.003680	1.33e-01	9.64e-01
APC/C:Cdc20 mediated degradation of Cyclin B	20	3.09e-01	4.38e-01	0.18200	0.163000	-0.081500	2.07e-01	5.29e-01
Activation of SMO	12	3.10e-01	4.38e-01	0.23300	-0.189000	0.135000	2.57e-01	4.17e-01
Interconversion of nucleotide di- and triphosphates	21	3.10e-01	4.38e-01	0.20600	-0.096500	-0.182000	4.44e-01	1.50e-01
Orc1 removal from chromatin	59	3.13e-01	4.41e-01	0.11800	0.115000	0.027700	1.28e-01	7.14e-01
Synthesis of PC	21	3.13e-01	4.41e-01	0.20500	-0.095500	-0.181000	4.49e-01	1.51e-01
Eukaryotic Translation Termination	55	3.14e-01	4.42e-01	0.12500	-0.048000	-0.115000	5.39e-01	1.39e-01
Adenylate cyclase inhibitory pathway	11	3.16e-01	4.45e-01	0.24600	-0.228000	0.090700	1.90e-01	6.03e-01
Synthesis of active ubiquitin: roles of E1 and E2 enzymes	25	3.17e-01	4.46e-01	0.15900	0.114000	-0.111000	3.26e-01	3.36e-01
The role of GTSE1 in G2/M progression after G2 checkpoint	48	3.20e-01	4.47e-01	0.13600	0.107000	0.084200	1.99e-01	3.13e-01
Fc epsilon receptor (FCERI) signaling	104	3.20e-01	4.47e-01	0.08720	0.015100	0.085900	7.91e-01	1.31e-01
Cyclin D associated events in G1	41	3.20e-01	4.47e-01	0.14600	0.078100	0.124000	3.87e-01	1.71e-01
G1 Phase	41	3.20e-01	4.47e-01	0.14600	0.078100	0.124000	3.87e-01	1.71e-01
PI3K Cascade	23	3.21e-01	4.47e-01	0.18200	0.015100	0.181000	9.01e-01	1.33e-01
Signaling by KIT in disease	17	3.21e-01	4.47e-01	0.19200	-0.139000	0.132000	3.21e-01	3.47e-01
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants	17	3.21e-01	4.47e-01	0.19200	-0.139000	0.132000	3.21e-01	3.47e-01
Stabilization of p53	48	3.23e-01	4.49e-01	0.12200	0.121000	-0.012200	1.48e-01	8.84e-01
FCERI mediated MAPK activation	23	3.23e-01	4.50e-01	0.17700	-0.005820	0.177000	9.61e-01	1.42e-01
Metalloprotease DUBs	15	3.28e-01	4.55e-01	0.22500	0.223000	0.033800	1.36e-01	8.21e-01
Interferon gamma signaling	44	3.29e-01	4.57e-01	0.11900	-0.059700	0.103000	4.94e-01	2.37e-01
Inactivation, recovery and regulation of the phototransduction cascade	13	3.31e-01	4.58e-01	0.21900	-0.102000	0.194000	5.26e-01	2.26e-01
The phototransduction cascade	13	3.31e-01	4.58e-01	0.21900	-0.102000	0.194000	5.26e-01	2.26e-01
Adherens junctions interactions	11	3.31e-01	4.58e-01	0.23800	-0.213000	0.107000	2.21e-01	5.41e-01
VEGFR2 mediated cell proliferation	16	3.34e-01	4.62e-01	0.19500	-0.159000	0.113000	2.72e-01	4.35e-01
Regulation of Complement cascade	13	3.35e-01	4.62e-01	0.22500	0.047700	-0.220000	7.66e-01	1.70e-01
Hyaluronan metabolism	11	3.37e-01	4.64e-01	0.24100	-0.072400	0.230000	6.78e-01	1.87e-01
WNT5A-dependent internalization of FZD4	13	3.38e-01	4.65e-01	0.21800	-0.196000	0.095200	2.22e-01	5.53e-01
RHO GTPases activate KTN1	10	3.41e-01	4.68e-01	0.28200	0.107000	0.261000	5.60e-01	1.53e-01
Autodegradation of Cdh1 by Cdh1:APC/C	58	3.42e-01	4.69e-01	0.10100	0.082100	-0.059500	2.80e-01	4.34e-01
Synthesis of PA	21	3.42e-01	4.70e-01	0.20000	-0.132000	-0.150000	2.95e-01	2.33e-01
Arachidonic acid metabolism	19	3.43e-01	4.70e-01	0.21000	-0.153000	-0.144000	2.47e-01	2.78e-01
Miscellaneous transport and binding events	16	3.46e-01	4.74e-01	0.19100	0.150000	-0.119000	2.99e-01	4.11e-01
Uptake and function of anthrax toxins	11	3.47e-01	4.74e-01	0.23700	-0.224000	0.077500	1.99e-01	6.56e-01
RMTs methylate histone arginines	28	3.48e-01	4.76e-01	0.14400	-0.103000	0.101000	3.46e-01	3.57e-01
Ribosomal scanning and start codon recognition	45	3.49e-01	4.76e-01	0.12700	0.125000	0.019200	1.47e-01	8.24e-01
Response of EIF2AK1 (HRI) to heme deficiency	14	3.51e-01	4.77e-01	0.23200	0.068200	0.222000	6.59e-01	1.51e-01
eNOS activation	10	3.51e-01	4.77e-01	0.24000	-0.183000	0.156000	3.17e-01	3.94e-01
GTP hydrolysis and joining of the 60S ribosomal subunit	73	3.51e-01	4.78e-01	0.08970	0.076100	-0.047400	2.62e-01	4.85e-01
Regulation of PTEN stability and activity	59	3.52e-01	4.79e-01	0.10700	0.107000	0.001910	1.54e-01	9.80e-01
Cyclin A:Cdk2-associated events at S phase entry	77	3.54e-01	4.80e-01	0.09850	0.094600	0.027700	1.52e-01	6.75e-01
Formation of a pool of free 40S subunits	63	3.55e-01	4.81e-01	0.10000	0.016800	-0.099000	8.18e-01	1.75e-01
Cytochrome P450 - arranged by substrate type	18	3.56e-01	4.82e-01	0.20600	-0.191000	-0.077300	1.62e-01	5.70e-01
MECP2 regulates neuronal receptors and channels	10	3.58e-01	4.84e-01	0.28100	0.154000	0.236000	4.01e-01	1.97e-01
Signaling by Erythropoietin	19	3.59e-01	4.84e-01	0.17400	-0.085800	0.152000	5.17e-01	2.53e-01
Pentose phosphate pathway	12	3.59e-01	4.84e-01	0.25900	0.167000	0.197000	3.16e-01	2.37e-01
IL-6-type cytokine receptor ligand interactions	10	3.59e-01	4.84e-01	0.25400	-0.253000	0.020900	1.67e-01	9.09e-01
Dopamine Neurotransmitter Release Cycle	11	3.62e-01	4.88e-01	0.24200	-0.015100	0.241000	9.31e-01	1.66e-01
Cap-dependent Translation Initiation	79	3.63e-01	4.88e-01	0.08450	0.068100	-0.050000	2.96e-01	4.44e-01
Eukaryotic Translation Initiation	79	3.63e-01	4.88e-01	0.08450	0.068100	-0.050000	2.96e-01	4.44e-01
Methylation	10	3.66e-01	4.91e-01	0.26400	-0.048600	-0.259000	7.90e-01	1.56e-01
RNA Polymerase III Transcription Termination	22	3.68e-01	4.93e-01	0.16300	0.154000	-0.052600	2.11e-01	6.70e-01
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis	46	3.68e-01	4.93e-01	0.11000	0.090700	-0.062200	2.88e-01	4.66e-01
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells	12	3.69e-01	4.93e-01	0.23700	0.031400	0.235000	8.50e-01	1.58e-01
NOTCH3 Activation and Transmission of Signal to the Nucleus	21	3.69e-01	4.93e-01	0.18100	-0.178000	-0.034300	1.58e-01	7.86e-01
Deactivation of the beta-catenin transactivating complex	32	3.69e-01	4.93e-01	0.13500	-0.044900	0.127000	6.60e-01	2.14e-01
ZBP1(DAI) mediated induction of type I IFNs	17	3.70e-01	4.93e-01	0.21000	0.094900	0.188000	4.99e-01	1.81e-01
Unwinding of DNA	10	3.70e-01	4.93e-01	0.24700	-0.035100	0.245000	8.47e-01	1.80e-01
Receptor Mediated Mitophagy	11	3.71e-01	4.93e-01	0.22700	0.205000	-0.097200	2.40e-01	5.77e-01
TNF signaling	34	3.71e-01	4.93e-01	0.13000	-0.123000	0.043700	2.15e-01	6.60e-01
Signaling by EGFR in Cancer	18	3.72e-01	4.93e-01	0.20600	0.112000	0.173000	4.13e-01	2.04e-01
Initiation of Nuclear Envelope (NE) Reformation	17	3.74e-01	4.95e-01	0.19700	0.196000	0.018400	1.62e-01	8.95e-01
Activation of the AP-1 family of transcription factors	10	3.74e-01	4.95e-01	0.25100	-0.007420	0.251000	9.68e-01	1.70e-01
Phosphorylation of the APC/C	18	3.76e-01	4.97e-01	0.17300	0.139000	-0.104000	3.08e-01	4.45e-01
Synthesis of glycosylphosphatidylinositol (GPI)	15	3.81e-01	5.03e-01	0.18800	0.131000	-0.135000	3.80e-01	3.66e-01
Glycosphingolipid metabolism	32	3.81e-01	5.03e-01	0.13000	-0.108000	0.072000	2.92e-01	4.81e-01
CD28 co-stimulation	25	3.82e-01	5.04e-01	0.14800	-0.060300	0.136000	6.02e-01	2.41e-01
Translation initiation complex formation	44	3.83e-01	5.05e-01	0.11900	0.119000	-0.001860	1.74e-01	9.83e-01
Inhibition of replication initiation of damaged DNA by RB1/E2F1	12	3.85e-01	5.06e-01	0.24500	0.220000	0.108000	1.88e-01	5.17e-01
G1/S DNA Damage Checkpoints	57	3.85e-01	5.06e-01	0.11000	0.105000	0.034800	1.72e-01	6.50e-01
Interleukin-7 signaling	12	3.85e-01	5.06e-01	0.21000	-0.168000	0.126000	3.15e-01	4.51e-01
Transcriptional regulation by RUNX2	99	3.89e-01	5.10e-01	0.07850	-0.002400	0.078400	9.67e-01	1.79e-01
mRNA decay by 5' to 3' exoribonuclease	14	3.89e-01	5.10e-01	0.19300	0.143000	-0.129000	3.55e-01	4.03e-01
Signaling by WNT in cancer	28	3.90e-01	5.10e-01	0.15400	0.036300	0.150000	7.40e-01	1.71e-01
Metabolism of steroids	93	3.91e-01	5.11e-01	0.07670	-0.071600	0.027600	2.34e-01	6.46e-01
Translocation of SLC2A4 (GLUT4) to the plasma membrane	50	3.92e-01	5.11e-01	0.12100	-0.096300	-0.073400	2.39e-01	3.70e-01
Centrosome maturation	71	3.92e-01	5.11e-01	0.09900	0.091400	0.037900	1.84e-01	5.81e-01
Recruitment of mitotic centrosome proteins and complexes	71	3.92e-01	5.11e-01	0.09900	0.091400	0.037900	1.84e-01	5.81e-01
Estrogen-dependent nuclear events downstream of ESR-membrane signaling	19	3.92e-01	5.11e-01	0.16500	-0.101000	0.130000	4.44e-01	3.27e-01
Ras activation upon Ca2+ influx through NMDA receptor	13	3.95e-01	5.14e-01	0.23100	-0.209000	-0.098600	1.92e-01	5.39e-01
Regulation of TP53 Activity through Association with Co-factors	12	3.96e-01	5.14e-01	0.22700	0.017600	0.226000	9.16e-01	1.75e-01
Autophagy	108	3.96e-01	5.14e-01	0.06900	0.047100	-0.050300	3.99e-01	3.67e-01
Gap-filling DNA repair synthesis and ligation in GG-NER	23	3.99e-01	5.17e-01	0.17400	0.155000	0.079100	1.99e-01	5.12e-01
Metabolism of nitric oxide: NOS3 activation and regulation	13	4.01e-01	5.19e-01	0.19700	-0.141000	0.137000	3.77e-01	3.94e-01
Hh mutants abrogate ligand secretion	47	4.01e-01	5.19e-01	0.11300	0.113000	0.002940	1.81e-01	9.72e-01
TGF-beta receptor signaling activates SMADs	29	4.02e-01	5.19e-01	0.15700	0.095000	0.125000	3.76e-01	2.46e-01
Other semaphorin interactions	14	4.03e-01	5.21e-01	0.19400	-0.183000	0.065900	2.37e-01	6.70e-01
NOTCH2 Activation and Transmission of Signal to the Nucleus	16	4.05e-01	5.23e-01	0.20800	-0.177000	-0.110000	2.21e-01	4.45e-01
Regulation of beta-cell development	17	4.08e-01	5.25e-01	0.17200	-0.087000	0.148000	5.35e-01	2.90e-01
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S	45	4.09e-01	5.26e-01	0.11300	0.113000	-0.003760	1.91e-01	9.65e-01
SCF(Skp2)-mediated degradation of p27/p21	52	4.11e-01	5.28e-01	0.11100	0.106000	0.035000	1.87e-01	6.62e-01
G1/S-Specific Transcription	21	4.11e-01	5.28e-01	0.18200	0.138000	0.119000	2.75e-01	3.44e-01
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)	13	4.13e-01	5.30e-01	0.19400	0.116000	-0.155000	4.69e-01	3.32e-01
Complement cascade	14	4.14e-01	5.31e-01	0.20300	-0.008390	-0.203000	9.57e-01	1.88e-01
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase	19	4.15e-01	5.31e-01	0.16000	0.116000	-0.109000	3.81e-01	4.09e-01
Signaling by ERBB2 in Cancer	18	4.18e-01	5.34e-01	0.17500	-0.012200	0.175000	9.28e-01	2.00e-01
Interleukin-12 signaling	31	4.20e-01	5.36e-01	0.13500	-0.000325	0.135000	9.98e-01	1.95e-01
LDL clearance	14	4.21e-01	5.37e-01	0.20400	0.022900	0.203000	8.82e-01	1.89e-01
Activation of kainate receptors upon glutamate binding	17	4.21e-01	5.37e-01	0.19300	-0.180000	-0.068400	1.98e-01	6.25e-01
CLEC7A (Dectin-1) signaling	80	4.22e-01	5.38e-01	0.08060	-0.018200	0.078600	7.78e-01	2.25e-01
Downregulation of TGF-beta receptor signaling	24	4.24e-01	5.39e-01	0.16800	0.115000	0.122000	3.29e-01	3.01e-01
MicroRNA (miRNA) biogenesis	22	4.24e-01	5.39e-01	0.16200	0.161000	0.015500	1.92e-01	9.00e-01
L13a-mediated translational silencing of Ceruloplasmin expression	71	4.25e-01	5.39e-01	0.08160	0.059200	-0.056200	3.90e-01	4.13e-01
Peptide ligand-binding receptors	22	4.27e-01	5.42e-01	0.14700	-0.071500	0.129000	5.62e-01	2.95e-01
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template	34	4.28e-01	5.42e-01	0.14000	0.112000	0.082900	2.58e-01	4.03e-01
Cyclin E associated events during G1/S transition	75	4.29e-01	5.42e-01	0.08760	0.086900	0.010800	1.94e-01	8.72e-01
Signaling by NOTCH3	38	4.29e-01	5.42e-01	0.11700	-0.116000	0.018300	2.18e-01	8.46e-01
TRAF6 mediated NF-kB activation	19	4.29e-01	5.42e-01	0.15800	-0.134000	0.082700	3.11e-01	5.33e-01
Purine salvage	13	4.30e-01	5.42e-01	0.20800	-0.207000	-0.015500	1.96e-01	9.23e-01
Glucagon-type ligand receptors	11	4.32e-01	5.44e-01	0.23800	-0.096200	-0.218000	5.81e-01	2.11e-01
Glycolysis	55	4.33e-01	5.45e-01	0.10100	0.101000	0.007330	1.98e-01	9.25e-01
Intraflagellar transport	35	4.35e-01	5.47e-01	0.12200	0.122000	-0.011400	2.13e-01	9.07e-01
RUNX2 regulates osteoblast differentiation	20	4.37e-01	5.49e-01	0.15700	-0.041200	0.151000	7.50e-01	2.42e-01
Rab regulation of trafficking	110	4.37e-01	5.49e-01	0.07360	0.020500	0.070700	7.11e-01	2.01e-01
Selenocysteine synthesis	56	4.39e-01	5.50e-01	0.10300	-0.030100	-0.098500	6.97e-01	2.03e-01
MTOR signalling	40	4.39e-01	5.50e-01	0.12700	-0.079200	-0.099300	3.86e-01	2.78e-01
RUNX3 regulates NOTCH signaling	13	4.39e-01	5.50e-01	0.21600	0.080200	0.201000	6.17e-01	2.11e-01
Regulation of RUNX2 expression and activity	61	4.41e-01	5.51e-01	0.08720	0.041100	-0.076900	5.79e-01	3.00e-01
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	57	4.41e-01	5.51e-01	0.09990	-0.018700	-0.098100	8.08e-01	2.01e-01
SUMOylation of DNA methylation proteins	15	4.42e-01	5.52e-01	0.20400	0.105000	0.175000	4.83e-01	2.40e-01
Gamma carboxylation, hypusine formation and arylsulfatase activation	28	4.43e-01	5.52e-01	0.15000	-0.084100	-0.124000	4.42e-01	2.55e-01
NOTCH4 Intracellular Domain Regulates Transcription	15	4.44e-01	5.52e-01	0.18700	0.001610	0.187000	9.91e-01	2.09e-01
Metabolic disorders of biological oxidation enzymes	13	4.44e-01	5.52e-01	0.22000	-0.180000	-0.127000	2.62e-01	4.28e-01
Defective CFTR causes cystic fibrosis	50	4.44e-01	5.52e-01	0.10000	0.099400	-0.013500	2.25e-01	8.69e-01
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	66	4.45e-01	5.52e-01	0.08360	-0.037900	0.074500	5.95e-01	2.96e-01
Hh mutants that don't undergo autocatalytic processing are degraded by ERAD	46	4.45e-01	5.52e-01	0.10500	0.104000	-0.012800	2.24e-01	8.81e-01
Tie2 Signaling	13	4.46e-01	5.52e-01	0.22100	0.158000	0.154000	3.24e-01	3.36e-01
G beta:gamma signalling through PLC beta	12	4.48e-01	5.52e-01	0.22700	-0.119000	-0.193000	4.75e-01	2.47e-01
Presynaptic function of Kainate receptors	12	4.48e-01	5.52e-01	0.22700	-0.119000	-0.193000	4.75e-01	2.47e-01
Diseases of programmed cell death	24	4.48e-01	5.52e-01	0.13900	-0.051800	0.129000	6.61e-01	2.75e-01
RIPK1-mediated regulated necrosis	22	4.49e-01	5.52e-01	0.14400	-0.131000	0.061000	2.90e-01	6.21e-01
Regulated Necrosis	22	4.49e-01	5.52e-01	0.14400	-0.131000	0.061000	2.90e-01	6.21e-01
Regulation of necroptotic cell death	22	4.49e-01	5.52e-01	0.14400	-0.131000	0.061000	2.90e-01	6.21e-01
Late endosomal microautophagy	23	4.49e-01	5.52e-01	0.14100	-0.127000	0.061400	2.94e-01	6.10e-01
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression	15	4.49e-01	5.52e-01	0.19600	0.061000	0.187000	6.83e-01	2.11e-01
Signaling by ERBB2 TMD/JMD mutants	14	4.51e-01	5.53e-01	0.17700	-0.106000	0.142000	4.91e-01	3.58e-01
NR1H2 and NR1H3-mediated signaling	34	4.51e-01	5.53e-01	0.11500	-0.098100	0.059100	3.23e-01	5.51e-01
Base Excision Repair	43	4.53e-01	5.55e-01	0.11600	0.109000	0.038200	2.15e-01	6.65e-01
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models	18	4.58e-01	5.60e-01	0.15500	-0.084400	0.130000	5.36e-01	3.38e-01
Neurodegenerative Diseases	18	4.58e-01	5.60e-01	0.15500	-0.084400	0.130000	5.36e-01	3.38e-01
MAPK targets/ Nuclear events mediated by MAP kinases	31	4.58e-01	5.60e-01	0.12600	-0.125000	0.011000	2.28e-01	9.16e-01
DNA Double Strand Break Response	37	4.62e-01	5.64e-01	0.12600	0.110000	0.061700	2.47e-01	5.16e-01
Signaling by NODAL	10	4.63e-01	5.65e-01	0.20700	-0.168000	0.120000	3.58e-01	5.11e-01
Cytosolic sulfonation of small molecules	11	4.64e-01	5.65e-01	0.20700	0.029400	-0.205000	8.66e-01	2.38e-01
Assembly of the pre-replicative complex	56	4.66e-01	5.67e-01	0.09910	0.094900	0.028800	2.20e-01	7.10e-01
RUNX1 regulates transcription of genes involved in differentiation of HSCs	55	4.66e-01	5.67e-01	0.10100	0.094600	0.035000	2.26e-01	6.54e-01
Regulation of RUNX3 expression and activity	47	4.67e-01	5.67e-01	0.10800	0.104000	0.029800	2.20e-01	7.24e-01
Acyl chain remodelling of PC	12	4.67e-01	5.67e-01	0.18700	0.111000	-0.151000	5.05e-01	3.66e-01
SARS-CoV-2 Infection	56	4.69e-01	5.69e-01	0.09610	0.013900	0.095100	8.57e-01	2.19e-01
Degradation of AXIN	47	4.70e-01	5.69e-01	0.10900	0.101000	0.040800	2.31e-01	6.29e-01
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism	10	4.71e-01	5.70e-01	0.24200	-0.197000	-0.140000	2.80e-01	4.44e-01
alpha-linolenic acid (ALA) metabolism	10	4.71e-01	5.70e-01	0.24200	-0.197000	-0.140000	2.80e-01	4.44e-01
Diseases associated with N-glycosylation of proteins	16	4.76e-01	5.75e-01	0.19100	0.130000	0.140000	3.68e-01	3.33e-01
TRAF6 mediated IRF7 activation	14	4.76e-01	5.75e-01	0.19200	0.036700	0.188000	8.12e-01	2.23e-01
Regulation of PTEN mRNA translation	11	4.77e-01	5.75e-01	0.22400	0.090400	0.205000	6.04e-01	2.40e-01
Regulation of RAS by GAPs	57	4.77e-01	5.75e-01	0.09900	0.088800	0.043600	2.47e-01	5.70e-01
Vif-mediated degradation of APOBEC3G	43	4.78e-01	5.75e-01	0.09830	0.085500	-0.048600	3.33e-01	5.82e-01
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha	55	4.79e-01	5.76e-01	0.08810	0.031600	-0.082200	6.86e-01	2.92e-01
Glucose metabolism	69	4.80e-01	5.77e-01	0.08720	-0.023400	-0.084000	7.38e-01	2.28e-01
C-type lectin receptors (CLRs)	94	4.83e-01	5.79e-01	0.06830	-0.016700	0.066200	7.81e-01	2.68e-01
Autodegradation of the E3 ubiquitin ligase COP1	44	4.84e-01	5.80e-01	0.09880	0.094800	-0.027700	2.77e-01	7.51e-01
Regulation of Apoptosis	45	4.89e-01	5.84e-01	0.09420	0.078200	-0.052400	3.64e-01	5.43e-01
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A	43	4.90e-01	5.84e-01	0.10200	0.101000	-0.011800	2.52e-01	8.94e-01
p53-Independent DNA Damage Response	43	4.90e-01	5.84e-01	0.10200	0.101000	-0.011800	2.52e-01	8.94e-01
p53-Independent G1/S DNA damage checkpoint	43	4.90e-01	5.84e-01	0.10200	0.101000	-0.011800	2.52e-01	8.94e-01
Recruitment of NuMA to mitotic centrosomes	70	4.91e-01	5.84e-01	0.08870	0.075000	0.047200	2.78e-01	4.95e-01
Cellular response to hypoxia	62	4.91e-01	5.84e-01	0.08090	0.034500	-0.073200	6.39e-01	3.19e-01
Formation of the ternary complex, and subsequently, the 43S complex	38	4.92e-01	5.84e-01	0.10400	0.096900	-0.037700	3.02e-01	6.87e-01
Resolution of D-Loop Structures	21	4.93e-01	5.84e-01	0.16300	0.118000	0.112000	3.50e-01	3.73e-01
Resolution of D-loop Structures through Holliday Junction Intermediates	21	4.93e-01	5.84e-01	0.16300	0.118000	0.112000	3.50e-01	3.73e-01
AUF1 (hnRNP D0) binds and destabilizes mRNA	46	4.93e-01	5.84e-01	0.10800	0.096700	0.047300	2.57e-01	5.79e-01
p53-Dependent G1 DNA Damage Response	56	4.93e-01	5.84e-01	0.09450	0.091700	0.022700	2.36e-01	7.69e-01
p53-Dependent G1/S DNA damage checkpoint	56	4.93e-01	5.84e-01	0.09450	0.091700	0.022700	2.36e-01	7.69e-01
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	13	4.99e-01	5.90e-01	0.20300	0.113000	0.169000	4.82e-01	2.91e-01
Role of phospholipids in phagocytosis	14	5.00e-01	5.91e-01	0.17100	-0.165000	0.046000	2.85e-01	7.66e-01
COPI-mediated anterograde transport	73	5.01e-01	5.91e-01	0.08330	0.027800	0.078500	6.82e-01	2.47e-01
Senescence-Associated Secretory Phenotype (SASP)	45	5.01e-01	5.91e-01	0.10700	0.046200	0.097000	5.92e-01	2.61e-01
Hedgehog ligand biogenesis	50	5.03e-01	5.92e-01	0.09990	0.094900	0.031200	2.46e-01	7.03e-01
RAS processing	18	5.07e-01	5.96e-01	0.15600	-0.156000	0.002350	2.53e-01	9.86e-01
Nucleobase catabolism	21	5.08e-01	5.96e-01	0.15200	-0.146000	-0.040300	2.47e-01	7.49e-01
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism	11	5.09e-01	5.96e-01	0.21900	-0.140000	-0.168000	4.20e-01	3.33e-01
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1	14	5.09e-01	5.96e-01	0.17300	0.172000	-0.019200	2.65e-01	9.01e-01
Constitutive Signaling by NOTCH1 HD Domain Mutants	11	5.09e-01	5.96e-01	0.20300	-0.202000	-0.024300	2.46e-01	8.89e-01
Signaling by NOTCH1 HD Domain Mutants in Cancer	11	5.09e-01	5.96e-01	0.20300	-0.202000	-0.024300	2.46e-01	8.89e-01
Aggrephagy	16	5.09e-01	5.96e-01	0.17300	0.046900	0.167000	7.45e-01	2.48e-01
Removal of the Flap Intermediate from the C-strand	17	5.10e-01	5.96e-01	0.15100	0.138000	-0.060600	3.25e-01	6.66e-01
Negative regulators of DDX58/IFIH1 signaling	29	5.10e-01	5.96e-01	0.11700	-0.113000	0.032200	2.94e-01	7.64e-01
Vpu mediated degradation of CD4	43	5.12e-01	5.98e-01	0.09350	0.081000	-0.046700	3.59e-01	5.96e-01
Oncogene Induced Senescence	29	5.13e-01	5.99e-01	0.13300	0.113000	0.070100	2.92e-01	5.14e-01
Golgi Cisternae Pericentriolar Stack Reorganization	11	5.18e-01	6.04e-01	0.21300	0.189000	0.098500	2.79e-01	5.72e-01
TNFR2 non-canonical NF-kB pathway	63	5.22e-01	6.08e-01	0.07790	-0.024300	0.074000	7.39e-01	3.10e-01
Early Phase of HIV Life Cycle	11	5.25e-01	6.11e-01	0.21400	0.149000	0.155000	3.93e-01	3.75e-01
UCH proteinases	74	5.26e-01	6.11e-01	0.08140	0.071700	0.038700	2.87e-01	5.66e-01
Signal amplification	20	5.29e-01	6.14e-01	0.15400	0.058800	0.142000	6.49e-01	2.72e-01
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	10	5.30e-01	6.15e-01	0.21900	0.194000	0.102000	2.88e-01	5.78e-01
Hedgehog 'on' state	71	5.36e-01	6.20e-01	0.08290	0.048200	0.067400	4.84e-01	3.27e-01
Gastrin-CREB signalling pathway via PKC and MAPK	15	5.36e-01	6.20e-01	0.16400	-0.000157	0.164000	9.99e-01	2.72e-01
G beta:gamma signalling through BTK	10	5.37e-01	6.21e-01	0.21000	-0.052000	-0.203000	7.76e-01	2.66e-01
AKT phosphorylates targets in the cytosol	14	5.38e-01	6.22e-01	0.16000	-0.148000	0.060500	3.39e-01	6.95e-01
Acyl chain remodelling of PE	11	5.39e-01	6.23e-01	0.18400	0.179000	-0.040700	3.04e-01	8.15e-01
Signaling by ERBB2 KD Mutants	17	5.40e-01	6.23e-01	0.14400	-0.062100	0.129000	6.58e-01	3.56e-01
Rap1 signalling	14	5.43e-01	6.26e-01	0.18100	0.078500	0.163000	6.11e-01	2.91e-01
Metabolism of polyamines	50	5.44e-01	6.27e-01	0.09000	0.089700	0.006350	2.73e-01	9.38e-01
Termination of translesion DNA synthesis	28	5.47e-01	6.29e-01	0.13000	0.091800	0.092400	4.01e-01	3.98e-01
TRAF3-dependent IRF activation pathway	12	5.47e-01	6.29e-01	0.16600	-0.114000	0.121000	4.95e-01	4.68e-01
Aberrant regulation of mitotic exit in cancer due to RB1 defects	20	5.52e-01	6.34e-01	0.13100	0.121000	-0.050300	3.50e-01	6.97e-01
Fatty acyl-CoA biosynthesis	18	5.54e-01	6.35e-01	0.13600	-0.062100	0.121000	6.49e-01	3.73e-01
Removal of the Flap Intermediate	14	5.55e-01	6.36e-01	0.16800	0.167000	0.019300	2.79e-01	9.00e-01
MAP3K8 (TPL2)-dependent MAPK1/3 activation	13	5.57e-01	6.37e-01	0.17000	-0.002050	0.170000	9.90e-01	2.88e-01
RORA activates gene expression	17	5.58e-01	6.38e-01	0.13700	-0.106000	0.087800	4.50e-01	5.31e-01
Phospholipid metabolism	150	5.59e-01	6.39e-01	0.05560	-0.038400	-0.040200	4.19e-01	3.98e-01
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	16	5.59e-01	6.39e-01	0.16000	0.040600	0.155000	7.79e-01	2.83e-01
COPI-independent Golgi-to-ER retrograde traffic	27	5.62e-01	6.41e-01	0.12000	0.011800	0.119000	9.15e-01	2.84e-01
Synthesis of IP2, IP, and Ins in the cytosol	12	5.65e-01	6.44e-01	0.17000	-0.033100	0.166000	8.43e-01	3.18e-01
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	19	5.69e-01	6.47e-01	0.13800	-0.005170	0.138000	9.69e-01	3.00e-01
Trafficking of GluR2-containing AMPA receptors	10	5.69e-01	6.47e-01	0.17900	-0.162000	0.075900	3.75e-01	6.78e-01
Amino acids regulate mTORC1	45	5.75e-01	6.53e-01	0.08290	-0.044700	0.069900	6.04e-01	4.18e-01
Dectin-1 mediated noncanonical NF-kB signaling	51	5.76e-01	6.54e-01	0.08880	0.083900	0.029200	3.01e-01	7.19e-01
Plasma lipoprotein clearance	21	5.80e-01	6.58e-01	0.12200	-0.110000	0.051700	3.83e-01	6.82e-01
Regulation of FZD by ubiquitination	11	5.83e-01	6.60e-01	0.16500	-0.101000	0.130000	5.61e-01	4.56e-01
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects	16	5.84e-01	6.60e-01	0.14500	-0.013800	0.144000	9.24e-01	3.17e-01
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)	16	5.84e-01	6.60e-01	0.14500	-0.013800	0.144000	9.24e-01	3.17e-01
Degradation of GLI1 by the proteasome	51	5.91e-01	6.68e-01	0.07580	0.062000	-0.043500	4.44e-01	5.91e-01
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants	50	5.94e-01	6.69e-01	0.07680	-0.067900	0.035700	4.07e-01	6.63e-01
Constitutive Signaling by NOTCH1 PEST Domain Mutants	50	5.94e-01	6.69e-01	0.07680	-0.067900	0.035700	4.07e-01	6.63e-01
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer	50	5.94e-01	6.69e-01	0.07680	-0.067900	0.035700	4.07e-01	6.63e-01
Signaling by NOTCH1 PEST Domain Mutants in Cancer	50	5.94e-01	6.69e-01	0.07680	-0.067900	0.035700	4.07e-01	6.63e-01
Signaling by NOTCH1 in Cancer	50	5.94e-01	6.69e-01	0.07680	-0.067900	0.035700	4.07e-01	6.63e-01
Energy dependent regulation of mTOR by LKB1-AMPK	29	5.98e-01	6.72e-01	0.11800	-0.077500	-0.089100	4.70e-01	4.07e-01
Apoptotic factor-mediated response	13	6.00e-01	6.74e-01	0.15700	-0.014800	0.156000	9.27e-01	3.30e-01
ABC transporter disorders	56	6.07e-01	6.80e-01	0.07090	0.034800	-0.061800	6.52e-01	4.25e-01
Ubiquitin-dependent degradation of Cyclin D	44	6.07e-01	6.80e-01	0.08740	0.086900	0.009040	3.19e-01	9.17e-01
ROS and RNS production in phagocytes	20	6.19e-01	6.93e-01	0.11900	-0.036600	0.113000	7.77e-01	3.83e-01
Gap junction trafficking and regulation	13	6.19e-01	6.93e-01	0.16000	0.033400	0.157000	8.35e-01	3.28e-01
Glycogen synthesis	12	6.20e-01	6.93e-01	0.17600	-0.144000	-0.099900	3.87e-01	5.49e-01
Growth hormone receptor signaling	17	6.21e-01	6.94e-01	0.12400	-0.083600	0.091800	5.51e-01	5.13e-01
VLDLR internalisation and degradation	11	6.22e-01	6.94e-01	0.17100	-0.170000	-0.023000	3.30e-01	8.95e-01
Regulation of activated PAK-2p34 by proteasome mediated degradation	42	6.22e-01	6.94e-01	0.08480	0.084600	-0.004810	3.43e-01	9.57e-01
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants	17	6.23e-01	6.94e-01	0.14600	0.076200	0.125000	5.86e-01	3.74e-01
Signaling by Ligand-Responsive EGFR Variants in Cancer	17	6.23e-01	6.94e-01	0.14600	0.076200	0.125000	5.86e-01	3.74e-01
Neddylation	200	6.26e-01	6.96e-01	0.04020	-0.005470	-0.039800	8.94e-01	3.34e-01
Endosomal Sorting Complex Required For Transport (ESCRT)	24	6.31e-01	7.01e-01	0.12300	0.080700	0.092300	4.94e-01	4.34e-01
G beta:gamma signalling through CDC42	13	6.32e-01	7.01e-01	0.15400	-0.016200	-0.153000	9.20e-01	3.39e-01
Prostacyclin signalling through prostacyclin receptor	12	6.37e-01	7.06e-01	0.17000	-0.089200	-0.145000	5.93e-01	3.86e-01
NIK-->noncanonical NF-kB signaling	50	6.37e-01	7.06e-01	0.07890	0.077700	0.013700	3.42e-01	8.67e-01
Budding and maturation of HIV virion	22	6.38e-01	7.06e-01	0.12300	0.047300	0.114000	7.01e-01	3.57e-01
Signaling by FGFR1 in disease	30	6.42e-01	7.10e-01	0.09990	0.012000	0.099200	9.09e-01	3.47e-01
FGFR1 mutant receptor activation	23	6.43e-01	7.10e-01	0.11100	-0.003790	0.111000	9.75e-01	3.58e-01
Activation of NF-kappaB in B cells	56	6.44e-01	7.10e-01	0.07840	0.062800	0.047000	4.17e-01	5.43e-01
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	27	6.44e-01	7.10e-01	0.11000	-0.100000	-0.045600	3.66e-01	6.82e-01
CD28 dependent PI3K/Akt signaling	17	6.50e-01	7.17e-01	0.12000	-0.055600	0.106000	6.92e-01	4.50e-01
Resolution of Abasic Sites (AP sites)	36	6.52e-01	7.18e-01	0.09520	0.082900	0.047000	3.90e-01	6.26e-01
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	36	6.53e-01	7.18e-01	0.09430	0.085300	0.040200	3.76e-01	6.77e-01
Class I MHC mediated antigen processing & presentation	303	6.54e-01	7.19e-01	0.03210	0.030800	0.009310	3.61e-01	7.82e-01
Metabolism of steroid hormones	12	6.55e-01	7.19e-01	0.14000	-0.117000	0.077200	4.84e-01	6.43e-01
HDACs deacetylate histones	30	6.56e-01	7.20e-01	0.10200	0.094300	0.038600	3.72e-01	7.14e-01
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	26	6.59e-01	7.22e-01	0.10900	0.044500	0.100000	6.95e-01	3.78e-01
Negative regulation of MAPK pathway	39	6.60e-01	7.23e-01	0.09140	0.057900	0.070800	5.32e-01	4.45e-01
SCF-beta-TrCP mediated degradation of Emi1	45	6.62e-01	7.24e-01	0.07170	0.061700	-0.036700	4.75e-01	6.71e-01
Retrograde neurotrophin signalling	11	6.63e-01	7.24e-01	0.16000	0.022800	0.158000	8.96e-01	3.65e-01
Signaling by ERBB2 ECD mutants	15	6.63e-01	7.24e-01	0.12500	-0.055300	0.112000	7.11e-01	4.54e-01
Gap junction trafficking	11	6.70e-01	7.31e-01	0.16700	0.089000	0.142000	6.09e-01	4.16e-01
Signaling by the B Cell Receptor (BCR)	85	6.79e-01	7.40e-01	0.05460	0.000958	0.054600	9.88e-01	3.85e-01
NOTCH3 Intracellular Domain Regulates Transcription	18	6.84e-01	7.45e-01	0.11000	-0.045600	0.099800	7.38e-01	4.64e-01
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling	20	6.86e-01	7.46e-01	0.12000	-0.104000	-0.060500	4.22e-01	6.40e-01
ER-Phagosome pathway	61	6.91e-01	7.51e-01	0.06390	0.063600	0.006460	3.91e-01	9.31e-01
Cell-cell junction organization	23	6.93e-01	7.53e-01	0.09730	-0.093800	0.025500	4.36e-01	8.32e-01
STING mediated induction of host immune responses	11	6.94e-01	7.53e-01	0.15000	0.149000	0.018300	3.93e-01	9.17e-01
Regulation of ornithine decarboxylase (ODC)	44	6.95e-01	7.54e-01	0.07020	0.067700	-0.018300	4.37e-01	8.33e-01
FOXO-mediated transcription of cell death genes	14	6.97e-01	7.55e-01	0.12800	-0.128000	0.004700	4.06e-01	9.76e-01
Constitutive Signaling by EGFRvIII	15	7.01e-01	7.57e-01	0.13000	0.035500	0.125000	8.12e-01	4.02e-01
Signaling by EGFRvIII in Cancer	15	7.01e-01	7.57e-01	0.13000	0.035500	0.125000	8.12e-01	4.02e-01
Processive synthesis on the C-strand of the telomere	19	7.01e-01	7.57e-01	0.10900	0.109000	-0.003370	4.09e-01	9.80e-01
Kinesins	24	7.03e-01	7.59e-01	0.10700	0.077000	0.074900	5.14e-01	5.26e-01
Glutamate Neurotransmitter Release Cycle	12	7.04e-01	7.59e-01	0.13300	-0.024800	0.131000	8.82e-01	4.32e-01
TP53 Regulates Transcription of Death Receptors and Ligands	11	7.08e-01	7.63e-01	0.14100	-0.008090	0.141000	9.63e-01	4.19e-01
Antigen processing-Cross presentation	69	7.10e-01	7.64e-01	0.06240	0.048600	0.039100	4.86e-01	5.75e-01
CD209 (DC-SIGN) signaling	17	7.10e-01	7.64e-01	0.10700	-0.048700	0.094900	7.28e-01	4.98e-01
Processive synthesis on the lagging strand	15	7.21e-01	7.75e-01	0.12400	0.121000	0.026700	4.19e-01	8.58e-01
Regulation of MECP2 expression and activity	26	7.22e-01	7.76e-01	0.09880	-0.078400	-0.060300	4.89e-01	5.95e-01
RAB GEFs exchange GTP for GDP on RABs	81	7.25e-01	7.78e-01	0.05580	0.033700	0.044500	6.01e-01	4.90e-01
Peptide hormone metabolism	39	7.28e-01	7.81e-01	0.07450	0.011200	0.073700	9.04e-01	4.26e-01
Transcriptional Regulation by VENTX	34	7.31e-01	7.83e-01	0.07440	0.072400	-0.017300	4.65e-01	8.61e-01
Aberrant regulation of mitotic cell cycle due to RB1 defects	35	7.32e-01	7.83e-01	0.08170	0.074300	0.034100	4.47e-01	7.27e-01
Diseases of mitotic cell cycle	35	7.32e-01	7.83e-01	0.08170	0.074300	0.034100	4.47e-01	7.27e-01
Signaling by Hedgehog	114	7.33e-01	7.84e-01	0.04290	0.004180	0.042700	9.39e-01	4.33e-01
GLI3 is processed to GLI3R by the proteasome	50	7.39e-01	7.88e-01	0.05820	0.049000	-0.031400	5.50e-01	7.02e-01
VxPx cargo-targeting to cilium	17	7.39e-01	7.88e-01	0.10100	-0.041500	0.091900	7.67e-01	5.12e-01
Asymmetric localization of PCP proteins	55	7.41e-01	7.90e-01	0.05500	0.044200	-0.032800	5.72e-01	6.75e-01
Protein methylation	10	7.43e-01	7.90e-01	0.13800	-0.004400	0.138000	9.81e-01	4.51e-01
BMAL1:CLOCK,NPAS2 activates circadian gene expression	24	7.43e-01	7.90e-01	0.08260	-0.064100	0.052100	5.87e-01	6.59e-01
Synthesis of very long-chain fatty acyl-CoAs	10	7.43e-01	7.90e-01	0.13900	0.002870	0.139000	9.87e-01	4.47e-01
Purine catabolism	14	7.43e-01	7.90e-01	0.12000	-0.119000	-0.016000	4.42e-01	9.18e-01
Adrenaline,noradrenaline inhibits insulin secretion	17	7.45e-01	7.90e-01	0.11700	-0.082900	-0.082300	5.54e-01	5.57e-01
Signaling by FGFR4 in disease	11	7.45e-01	7.90e-01	0.12500	-0.042900	0.117000	8.06e-01	5.02e-01
Competing endogenous RNAs (ceRNAs) regulate PTEN translation	10	7.48e-01	7.92e-01	0.14400	0.041200	0.138000	8.22e-01	4.49e-01
TP53 Regulates Transcription of Cell Death Genes	34	7.60e-01	8.04e-01	0.06950	-0.067400	0.017000	4.97e-01	8.64e-01
Cross-presentation of soluble exogenous antigens (endosomes)	40	7.68e-01	8.11e-01	0.06190	0.058000	-0.021700	5.26e-01	8.12e-01
Nuclear signaling by ERBB4	20	7.68e-01	8.11e-01	0.08580	-0.072800	0.045400	5.73e-01	7.25e-01
RA biosynthesis pathway	11	7.78e-01	8.21e-01	0.11200	-0.068000	0.089400	6.96e-01	6.08e-01
FCERI mediated NF-kB activation	65	7.79e-01	8.22e-01	0.05460	0.045300	0.030500	5.29e-01	6.71e-01
Insulin processing	19	7.80e-01	8.22e-01	0.09850	0.090200	0.039600	4.96e-01	7.65e-01
Selenoamino acid metabolism	68	7.84e-01	8.26e-01	0.05060	-0.013500	-0.048700	8.48e-01	4.88e-01
Formation of Fibrin Clot (Clotting Cascade)	13	7.86e-01	8.27e-01	0.12000	0.073300	0.095200	6.47e-01	5.52e-01
Depolymerisation of the Nuclear Lamina	13	7.87e-01	8.27e-01	0.12000	0.091300	0.078100	5.69e-01	6.26e-01
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	18	7.92e-01	8.32e-01	0.09030	-0.006640	0.090100	9.61e-01	5.09e-01
Transferrin endocytosis and recycling	21	7.94e-01	8.34e-01	0.07800	0.044400	-0.064100	7.25e-01	6.11e-01
Antigen processing: Ubiquitination & Proteasome degradation	265	8.04e-01	8.43e-01	0.02160	0.017600	-0.012500	6.24e-01	7.28e-01
Downregulation of ERBB2 signaling	18	8.10e-01	8.48e-01	0.08270	-0.027100	0.078200	8.43e-01	5.66e-01
Repression of WNT target genes	11	8.11e-01	8.49e-01	0.12000	0.057900	0.105000	7.40e-01	5.45e-01
G-protein beta:gamma signalling	20	8.12e-01	8.49e-01	0.08950	-0.076400	-0.046500	5.54e-01	7.19e-01
Regulated proteolysis of p75NTR	11	8.14e-01	8.51e-01	0.11900	0.058300	0.104000	7.38e-01	5.50e-01
Response of EIF2AK4 (GCN2) to amino acid deficiency	63	8.15e-01	8.51e-01	0.05050	-0.031200	-0.039700	6.69e-01	5.86e-01
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest	14	8.21e-01	8.56e-01	0.10300	0.047600	0.091700	7.58e-01	5.52e-01
WNT ligand biogenesis and trafficking	12	8.22e-01	8.57e-01	0.10300	-0.103000	-0.002260	5.37e-01	9.89e-01
MAPK6/MAPK4 signaling	73	8.25e-01	8.59e-01	0.04560	0.034600	0.029800	6.10e-01	6.60e-01
mTORC1-mediated signalling	23	8.27e-01	8.60e-01	0.07690	-0.021700	-0.073800	8.57e-01	5.40e-01
Degradation of GLI2 by the proteasome	50	8.32e-01	8.65e-01	0.04510	0.030400	-0.033300	7.10e-01	6.84e-01
Activated NOTCH1 Transmits Signal to the Nucleus	24	8.34e-01	8.66e-01	0.06480	-0.051300	0.039600	6.64e-01	7.37e-01
Iron uptake and transport	43	8.36e-01	8.68e-01	0.05630	-0.049400	-0.027000	5.76e-01	7.60e-01
Signaling by ERBB4	37	8.38e-01	8.69e-01	0.05750	0.010700	0.056500	9.10e-01	5.52e-01
Tight junction interactions	11	8.47e-01	8.78e-01	0.09110	0.071900	-0.055900	6.80e-01	7.48e-01
Nicotinamide salvaging	12	8.52e-01	8.81e-01	0.10300	-0.069900	-0.075000	6.75e-01	6.53e-01
Cytochrome c-mediated apoptotic response	10	8.52e-01	8.81e-01	0.09990	-0.010300	0.099400	9.55e-01	5.86e-01
Glutathione synthesis and recycling	10	8.53e-01	8.82e-01	0.09340	-0.061800	0.069900	7.35e-01	7.02e-01
Cleavage of the damaged pyrimidine	14	8.57e-01	8.83e-01	0.07790	0.053600	-0.056600	7.29e-01	7.14e-01
Depyrimidination	14	8.57e-01	8.83e-01	0.07790	0.053600	-0.056600	7.29e-01	7.14e-01
Recognition and association of DNA glycosylase with site containing an affected pyrimidine	14	8.57e-01	8.83e-01	0.07790	0.053600	-0.056600	7.29e-01	7.14e-01
RHO GTPases Activate NADPH Oxidases	13	8.63e-01	8.88e-01	0.07910	-0.059500	0.052100	7.10e-01	7.45e-01
Negative regulation of NOTCH4 signaling	47	8.64e-01	8.89e-01	0.04250	0.039400	-0.015800	6.41e-01	8.51e-01
Degradation of DVL	48	8.65e-01	8.90e-01	0.04170	0.016200	-0.038400	8.46e-01	6.46e-01
ERKs are inactivated	13	8.66e-01	8.90e-01	0.08240	-0.081400	0.012500	6.12e-01	9.38e-01
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	23	8.70e-01	8.93e-01	0.06900	0.045800	0.051600	7.04e-01	6.69e-01
NRIF signals cell death from the nucleus	13	8.73e-01	8.96e-01	0.08970	0.075400	0.048500	6.38e-01	7.62e-01
Downstream signaling events of B Cell Receptor (BCR)	67	8.80e-01	9.02e-01	0.03360	-0.009050	0.032400	8.98e-01	6.47e-01
G beta:gamma signalling through PI3Kgamma	15	8.92e-01	9.14e-01	0.07700	-0.062000	-0.045700	6.78e-01	7.59e-01
ADP signalling through P2Y purinoceptor 12	13	8.97e-01	9.17e-01	0.06780	0.048300	-0.047500	7.63e-01	7.67e-01
G-protein activation	13	8.97e-01	9.17e-01	0.06780	0.048300	-0.047500	7.63e-01	7.67e-01
Insulin receptor recycling	17	8.99e-01	9.19e-01	0.06680	0.018100	0.064300	8.97e-01	6.47e-01
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	11	9.01e-01	9.19e-01	0.08640	0.059300	0.062900	7.34e-01	7.18e-01
Signaling by ROBO receptors	151	9.06e-01	9.24e-01	0.02150	-0.021000	-0.004770	6.58e-01	9.20e-01
Ca2+ pathway	45	9.17e-01	9.33e-01	0.03880	-0.022700	-0.031400	7.92e-01	7.16e-01
Cleavage of the damaged purine	10	9.18e-01	9.33e-01	0.07730	0.075700	0.016000	6.79e-01	9.30e-01
Depurination	10	9.18e-01	9.33e-01	0.07730	0.075700	0.016000	6.79e-01	9.30e-01
Recognition and association of DNA glycosylase with site containing an affected purine	10	9.18e-01	9.33e-01	0.07730	0.075700	0.016000	6.79e-01	9.30e-01
Base-Excision Repair, AP Site Formation	16	9.19e-01	9.33e-01	0.05410	0.030900	-0.044500	8.31e-01	7.58e-01
Signaling by NOTCH4	70	9.25e-01	9.39e-01	0.02930	0.025100	0.015100	7.17e-01	8.28e-01
Thromboxane signalling through TP receptor	14	9.27e-01	9.40e-01	0.06420	0.055100	0.032900	7.21e-01	8.31e-01
Endogenous sterols	13	9.32e-01	9.44e-01	0.06490	-0.054300	-0.035400	7.35e-01	8.25e-01
Maturation of nucleoprotein	10	9.37e-01	9.48e-01	0.06600	-0.005810	-0.065700	9.75e-01	7.19e-01
Hedgehog 'off' state	87	9.48e-01	9.59e-01	0.02120	0.020000	0.006920	7.47e-01	9.11e-01
PCP/CE pathway	79	9.50e-01	9.60e-01	0.01900	-0.013200	0.013600	8.39e-01	8.34e-01
Signaling by NOTCH2	24	9.61e-01	9.71e-01	0.03040	-0.026100	0.015600	8.25e-01	8.95e-01
SARS-CoV-1 Infection	40	9.66e-01	9.74e-01	0.02590	-0.022000	-0.013600	8.10e-01	8.82e-01
ADP signalling through P2Y purinoceptor 1	15	9.67e-01	9.74e-01	0.03710	-0.036500	0.006950	8.07e-01	9.63e-01
Diseases associated with glycosylation precursor biosynthesis	18	9.67e-01	9.74e-01	0.03590	0.035100	0.007180	7.96e-01	9.58e-01
Disorders of Developmental Biology	10	9.71e-01	9.75e-01	0.04730	-0.041200	-0.023100	8.21e-01	8.99e-01
Disorders of Nervous System Development	10	9.71e-01	9.75e-01	0.04730	-0.041200	-0.023100	8.21e-01	8.99e-01
Loss of function of MECP2 in Rett syndrome	10	9.71e-01	9.75e-01	0.04730	-0.041200	-0.023100	8.21e-01	8.99e-01
Pervasive developmental disorders	10	9.71e-01	9.75e-01	0.04730	-0.041200	-0.023100	8.21e-01	8.99e-01
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux	29	9.77e-01	9.80e-01	0.02460	0.021200	0.012600	8.44e-01	9.06e-01
RAF activation	34	9.82e-01	9.84e-01	0.02070	-0.016700	-0.012200	8.66e-01	9.02e-01
Beta-catenin independent WNT signaling	117	9.88e-01	9.89e-01	0.00825	-0.008240	0.000487	8.78e-01	9.93e-01
Synthesis of pyrophosphates in the cytosol	10	9.93e-01	9.94e-01	0.01970	0.007670	-0.018200	9.67e-01	9.21e-01
Signaling by cytosolic FGFR1 fusion mutants	17	9.95e-01	9.95e-01	0.01370	-0.003780	0.013200	9.79e-01	9.25e-01

---

Detailed Gene set reports

Metabolism of RNA

Metabolism of RNA

metric	value
setSize	567
pMANOVA	3.29e-49
p.adjustMANOVA	4.05e-46
s.dist	0.38
s.human	0.37
s.mouse	0.0883
p.human	2.72e-50
p.mouse	0.000391

Top 20 genes

Gene	human	mouse
HSPA1A	4887	5534.5
CLP1	4787	5453.0
DDX21	4868	5307.0
HEATR1	4911	5214.0
UTP14A	4777	5328.5
WDR43	4883	4985.0
PDCD7	4447	5401.0
DCAF13	4800	4904.0
NUP98	4235	5486.0
CDC40	4670	4950.0
PRPF40A	4797	4800.0
GTF2F1	4999	4439.0
WDR3	4838	4572.0
ALYREF	5008	4414.0
ETF1	3946	5448.0
NUP54	4508	4751.0
POLR2A	3861	5366.0
WBP11	4711	4365.0
GTF2F2	4067	5047.0
BUD31	4578	4482.0

Click HERE to show all gene set members

All member genes

	human	mouse
AAAS	-3476	40.0
ACTB	940	5427.0
ADAR	-3014	581.0
ADARB1	-4854	2231.0
ADAT1	3686	-2288.0
ADAT2	-3238	-1700.0
ADAT3	3262	3799.0
AKT1	-4954	1242.0
ALKBH8	1989	1522.0
ALYREF	5008	4414.0
APOBEC2	-5343	-2332.0
AQR	3952	4831.0
BCAS2	4926	-4687.0
BMS1	3511	-3149.0
BUD31	4578	4482.0
BYSL	2701	1718.0
C1D	3347	-1555.0
C2orf49	3037	-2593.0
CASC3	9	2673.0
CCAR1	3856	1341.0
CCNH	3825	-1939.0
CD2BP2	2749	-2336.0
CD44	837	5375.0
CDC40	4670	4950.0
CDC5L	2693	369.0
CDK7	1571	326.0
CDKAL1	240	-2026.0
CHERP	4498	2639.0
CHTOP	-574	2577.0
CLNS1A	155	1480.0
CLP1	4787	5453.0
CNOT1	4456	1508.0
CNOT10	1314	-2583.0
CNOT11	2698	1032.0
CNOT2	3263	518.0
CNOT3	857	2288.0
CNOT4	2350	1422.0
CNOT6	1509	4740.0
CNOT6L	-2201	3671.0
CNOT7	1298	2117.0
CNOT8	3240	-3842.0
CPSF1	-3670	977.0
CPSF2	-922	-1111.0
CPSF3	1953	2237.0
CPSF4	862	4202.0
CPSF7	407	-1612.0
CRNKL1	4682	3910.0
CSNK1D	-3539	4717.0
CSNK1E	-5045	3424.0
CSTF1	2216	1705.0
CSTF2	1437	-1058.0
CSTF2T	2703	4379.0
CSTF3	-2793	4119.0
CTNNBL1	-145	476.0
CTU1	1091	-2555.0
CTU2	-805	3378.0
CWC15	4989	-1054.0
CWC22	4974	3088.0
CWC27	1809	-408.0
DCAF13	4800	4904.0
DCP1B	-2739	-1530.0
DCP2	3899	1030.0
DCPS	-2174	-1544.0
DDX1	3013	-711.0
DDX20	4951	1841.0
DDX21	4868	5307.0
DDX23	-645	-2684.0
DDX39A	3417	-377.0
DDX39B	984	839.0
DDX42	2929	4353.0
DDX46	2094	-964.0
DDX47	3735	-2506.0
DDX49	2178	4308.0
DDX5	4191	-363.0
DDX6	3301	1173.0
DHX15	2483	4871.0
DHX16	3981	2235.0
DHX37	2105	3594.0
DHX38	2857	440.0
DHX9	4151	2848.0
DIEXF	4877	-510.0
DIMT1	2537	42.0
DIS3	4973	2795.0
DKC1	3629	1648.0
DNAJC8	4247	-942.0
EBNA1BP2	4030	-1624.0
EDC3	599	-1248.0
EDC4	-3350	3819.0
EFTUD2	1157	3779.0
EIF4A1	2916	5463.0
EIF4A2	1360	849.0
EIF4A3	4491	2615.0
EIF4B	993	-2864.0
EIF4E	2892	2481.0
EIF4G1	-2988	-962.0
ELAC2	1520	1770.0
ELAVL1	2256	1752.0
ENPP2	3080	-3545.0
ERCC2	824	4319.0
ERCC3	473	3200.0
ERI1	2910	2565.0
ETF1	3946	5448.0
EXOSC1	1073	3516.0
EXOSC10	4991	3582.0
EXOSC2	3309	2709.0
EXOSC3	3331	784.0
EXOSC4	2447	-3953.0
EXOSC5	20	-4477.0
EXOSC7	-4980	-1705.0
EXOSC8	3102	1509.0
EXOSC9	4106	-1160.0
FAM98B	3022	-1641.0
FAU	2272	2649.0
FBL	4233	-132.0
FCF1	3303	1429.0
FIP1L1	3587	3058.0
FTSJ1	-980	-2230.0
FTSJ3	4444	4129.0
FUS	867	4530.0
FYTTD1	3374	4804.0
GAR1	4132	4232.0
GCFC2	4300	2962.0
GEMIN2	3264	-1925.0
GEMIN5	4699	2018.0
GEMIN6	3429	314.0
GEMIN7	2344	2502.0
GEMIN8	94	1167.0
GLE1	586	-1322.0
GNL3	4434	3896.0
GPKOW	590	4338.0
GSPT1	1495	2169.0
GTF2F1	4999	4439.0
GTF2F2	4067	5047.0
GTF2H1	3886	647.0
GTF2H2	4419	-2426.5
GTF2H3	-1925	-664.0
GTF2H5	-878	-3245.0
GTPBP3	-946	-1893.0
HBS1L	2208	1857.0
HEATR1	4911	5214.0
HNRNPA0	2412	2009.0
HNRNPA1	3878	4262.0
HNRNPA2B1	3693	-4286.0
HNRNPA3	2505	2004.0
HNRNPC	3406	-403.0
HNRNPD	4343	3267.0
HNRNPF	4978	3406.0
HNRNPH1	3339	5250.0
HNRNPH2	2261	-2683.0
HNRNPK	3054	2807.0
HNRNPL	1064	-948.0
HNRNPM	4022	-4783.0
HNRNPR	4406	3418.0
HNRNPU	4229	4805.0
HNRNPUL1	2433	-725.0
HSD17B10	-1193	-1970.0
HSPA1A	4887	5534.5
HSPA8	3674	5419.0
HSPB1	-4869	5539.0
IGF2	-4754	2227.0
IGF2BP2	-3031	5481.0
IMP3	4536	-4210.0
IMP4	2805	4037.0
ISG20L2	3385	4842.0
ISY1	2662	-330.0
KHSRP	4775	4199.0
KRR1	3921	-1381.0
LAGE3	-2536	-2661.0
LAS1L	3707	-585.0
LCMT2	3818	1412.0
LSM1	2752	-2128.0
LSM10	-3826	1128.0
LSM11	-2895	-1506.0
LSM2	-1347	-1539.0
LSM3	2210	-2101.0
LSM4	-2884	-2935.0
LSM5	2324	-1400.0
LSM6	-1177	-3681.0
LSM7	-3487	279.0
LTV1	4806	3706.0
MAGOH	4561	555.0
MAGOHB	2239	-1880.0
MAPK11	-3385	1370.0
MAPK14	-1562	-2824.0
MAPKAPK2	-2489	-1825.0
METTL1	1425	4955.0
METTL14	4358	-3888.0
METTL3	-3688	-708.0
MNAT1	830	-3106.0
MPHOSPH10	3928	2821.0
MPHOSPH6	2298	-1743.0
MT-CO1	-3167	-4401.0
MT-CYB	-1355	-4115.0
MT-ND1	-353	-4097.0
MT-ND2	-1120	-4098.0
MT-ND4	-2086	-3521.0
MT-ND5	-3244	-3936.0
MT-ND6	816	-5003.0
MTO1	3000	-4514.0
MYC	3994	185.0
NAT10	3642	2679.0
NCBP1	-1736	4720.0
NCBP2	4188	-2519.0
NCL	3573	4049.0
NDC1	1273	-322.0
NHP2	694	1773.0
NIP7	3751	2356.0
NOB1	3229	2731.0
NOC4L	1763	-2682.0
NOL11	4916	1935.0
NOL6	3819	4849.0
NOL9	4679	688.0
NOP10	1336	-894.0
NOP14	1590	4297.0
NOP2	3472	5052.0
NOP56	3099	3605.0
NOP58	4891	3903.0
NSUN2	3979	-500.0
NSUN4	-830	-4482.0
NSUN6	-148	-3602.0
NT5C3B	-4265	600.0
NUDT21	3626	432.0
NUP107	3232	3195.0
NUP133	889	-2580.0
NUP153	4762	4031.0
NUP155	4306	2897.0
NUP160	3998	2314.0
NUP188	2117	4593.0
NUP205	4438	3917.0
NUP214	3124	1845.0
NUP35	4571	2515.0
NUP37	-327	-873.0
NUP43	4562	193.0
NUP54	4508	4751.0
NUP85	3181	227.0
NUP88	1244	1407.0
NUP93	-1503	5229.0
NUP98	4235	5486.0
NXF1	4992	-1556.0
NXT1	1765	3075.0
OSGEP	-3005	-2926.0
PAIP1	4308	2767.0
PAN2	-4358	-3515.0
PAN3	-99	-1361.0
PARN	3874	1958.0
PATL1	3672	4864.0
PCBP1	-3158	-362.0
PCF11	-1597	-2273.0
PDCD11	-1465	862.0
PDCD7	4447	5401.0
PELP1	2605	1451.0
PES1	4214	1923.0
PHAX	4729	-485.0
PHF5A	3478	-940.0
PLRG1	4237	-1621.0
PNO1	4623	-406.0
PNRC2	2568	-4311.0
POLDIP3	-1320	5061.0
POLR2A	3861	5366.0
POLR2B	4509	-3401.0
POLR2C	4529	-4002.0
POLR2D	1669	3230.0
POLR2E	-667	148.0
POLR2G	89	4349.0
POLR2H	-3927	2213.0
POLR2I	-154	-2504.0
POLR2K	2480	-3599.0
POLR2L	-4314	-1126.0
POP1	-89	-604.0
POP4	-1436	311.0
POP5	3528	2328.0
POP7	386	-309.0
PPIE	2144	-1849.0
PPIH	594	-591.0
PPIL1	863	2264.0
PPIL3	4044	-732.0
PPIL4	3657	-3268.0
PPP2CA	4482	1672.0
PPP2R1A	-4013	-681.0
PPP2R2A	2264	1164.0
PPWD1	2992	-3786.0
PQBP1	-379	-3113.0
PRCC	2656	-830.0
PRKCA	-2938	1125.0
PRKCD	-4276	1141.0
PRMT5	933	2092.0
PRPF19	2441	-4795.0
PRPF3	4719	3434.0
PRPF31	1339	3842.0
PRPF38A	4433	-314.0
PRPF4	3652	-1807.0
PRPF40A	4797	4800.0
PRPF6	684	3858.0
PRPF8	2926	-1861.0
PSMA1	2820	4043.0
PSMA3	3434	-1035.0
PSMA4	769	-1962.0
PSMA6	2199	-1657.0
PSMA7	-2980	-1038.0
PSMB1	954	-1037.0
PSMB10	-1800	-831.0
PSMB2	618	-67.0
PSMB4	-235	-559.0
PSMB5	-4113	-2597.0
PSMB6	-793	-1795.0
PSMB7	-831	-2699.0
PSMB8	-675	-2510.0
PSMB9	-1611	-3558.0
PSMC1	449	1146.0
PSMC2	-1311	3386.0
PSMC3	-2439	-1846.0
PSMC4	2724	-205.0
PSMC5	1212	-1680.0
PSMC6	-2520	3114.0
PSMD1	2619	3210.0
PSMD10	-1227	361.0
PSMD11	995	5504.0
PSMD12	3831	-462.0
PSMD13	821	532.0
PSMD14	-635	3746.0
PSMD2	-713	741.0
PSMD3	-3343	-354.0
PSMD4	-214	968.0
PSMD5	1807	4479.0
PSMD6	3537	-3784.0
PSMD7	-2329	410.0
PSMD8	-3171	4292.0
PSMD9	4204	-3586.0
PSME1	-2771	-2861.0
PSME2	-4085	-41.0
PSME3	3333	491.0
PSME4	1960	2319.0
PSMF1	683	-1768.0
PTBP1	3063	4580.0
PUF60	-2093	174.0
PUS1	1845	3572.0
PUS3	4566	1659.0
PUS7	-584	994.0
PWP2	2462	1711.0
QTRT1	-3825	1120.0
RAE1	4471	3078.0
RAN	2329	575.0
RANBP2	4470	-562.0
RBM17	2520	872.0
RBM22	709	1413.0
RBM28	4327	-99.0
RBM5	3930	2323.0
RCL1	3257	237.0
RIOK1	3760	-572.0
RIOK3	-1480	1085.0
RNGTT	4414	-1456.0
RNMT	4864	3622.0
RNPC3	-3052	2613.0
RNPS1	681	-2204.0
RPL10	-3902	3923.0
RPL11	-2249	-1971.0
RPL14	433	-875.0
RPL18	-1782	448.0
RPL18A	-2969	-320.0
RPL19	-502	-1379.0
RPL22	1231	-3446.0
RPL22L1	3380	2374.0
RPL23	-115	-2882.0
RPL26	1047	696.0
RPL28	-391	-1891.0
RPL3	-786	5412.0
RPL30	286	-3056.0
RPL31	-595	2894.0
RPL32	-367	-950.0
RPL34	1447	-1314.0
RPL35A	812	-1471.0
RPL36A	1261	-1408.0
RPL37	-715	-1311.0
RPL37A	-1043	554.0
RPL38	231	-953.0
RPL3L	-5212	-4614.0
RPL4	-522	-571.0
RPL5	1206	3360.0
RPL7	1440	-1894.0
RPL8	-2775	-928.0
RPLP2	-2469	-3389.0
RPP14	2370	-2951.0
RPP30	2968	1603.0
RPP38	3980	480.0
RPP40	3369	-2381.0
RPS11	-1582	-458.0
RPS12	-318	1501.0
RPS13	1131	-1994.0
RPS14	-1412	122.0
RPS15	-1799	-1082.0
RPS15A	-704	-237.0
RPS16	-1828	2010.0
RPS18	-974	-1404.0
RPS19	-2045	-882.0
RPS20	-1844	1712.0
RPS21	-1536	-2810.0
RPS23	-68	-749.0
RPS24	256	-1505.0
RPS26	-282	-1421.0
RPS27A	783	-2165.0
RPS27L	-616	-69.0
RPS29	-1140	-1275.0
RPS3	-544	116.0
RPS4X	83	97.0
RPS5	-1577	935.0
RPS6	-245	1237.0
RPS8	-1593	-1231.0
RPS9	-1107	-2477.0
RQCD1	4265	2047.0
RRP1	1063	-4885.0
RRP36	1532	29.0
RRP7A	2138	4236.0
RRP9	771	1609.0
RTCB	581	-1646.0
SARNP	569	-1380.0
SART1	759	4758.0
SEC13	730	938.0
SEH1L	1085	4110.0
SENP3	2112	2776.0
SET	3683	1612.0
SF1	4412	2651.0
SF3A1	3470	3133.0
SF3A2	2302	714.0
SF3A3	2871	2458.0
SF3B1	1067	5041.0
SF3B2	2676	-3889.0
SF3B3	3615	4672.0
SF3B4	4792	3548.0
SF3B5	1969	817.0
SKIV2L	134	721.0
SLBP	2666	4469.0
SLU7	4893	2372.0
SMG1	3321	-674.0
SMG5	-910	815.0
SMG6	258	2929.0
SMG7	1383	1717.0
SMG8	4625	157.0
SMG9	-2328	3015.0
SMN1	4028	2156.5
SMNDC1	4537	2663.0
SNRNP200	2626	-3296.0
SNRNP25	2402	-2311.0
SNRNP27	2641	-3959.0
SNRNP35	-2744	-4385.0
SNRNP40	2967	2772.0
SNRNP48	4305	-1488.0
SNRNP70	-267	-2283.0
SNRPA1	4117	3762.0
SNRPB	3761	-2577.0
SNRPB2	4617	677.0
SNRPC	3677	-3134.0
SNRPD1	3996	1707.0
SNRPD2	2043	-2933.0
SNRPD3	2384	-3590.0
SNRPE	3421	-1387.0
SNRPF	3777	-2345.0
SNRPG	3179	3068.0
SNRPN	-2163	-1518.0
SNUPN	2836	1926.0
SNW1	3618	4892.0
SRRM1	2285	-2017.0
SRRM2	-1731	-1080.0
SRRT	4962	350.0
SRSF1	1871	-1493.0
SRSF11	3911	-1990.0
SRSF3	2586	1697.0
SRSF4	1929	3741.0
SRSF5	1997	-3060.0
SRSF6	1798	2387.0
SRSF7	3545	2132.0
SRSF9	3543	2675.0
SUGP1	-1552	-1352.0
SUPT5H	1321	4377.0
SYF2	4472	-819.0
SYMPK	-3207	-1626.0
TBL3	-1551	3495.0
TEX10	2840	3253.0
TFB1M	1537	-2725.0
TFIP11	5002	2826.0
TGS1	4576	2855.0
THADA	3513	-198.0
THG1L	453	3394.0
THOC1	2868	2971.0
THOC2	4510	561.0
THOC3	2831	-3387.0
THOC5	4842	-589.0
THOC6	-904	2005.0
THOC7	-873	-3232.0
THUMPD1	4666	-558.0
TNKS1BP1	-4407	3365.0
TNPO1	3184	5474.0
TP53RK	3992	-1473.0
TPR	2984	275.0
TPRKB	4453	2876.0
TRA2B	4288	3562.0
TRDMT1	2027	-1651.0
TRIT1	2894	1063.0
TRMT1	2897	-235.0
TRMT10A	1802	3925.0
TRMT10C	4780	1827.0
TRMT11	3034	1600.0
TRMT12	3365	4045.0
TRMT13	2904	-2313.0
TRMT44	2292	932.0
TRMT5	-517	4966.0
TRMT6	4499	3527.0
TRMT61A	-2849	4239.0
TRMU	2385	-4882.0
TRNT1	3318	1625.0
TSEN15	3354	-2289.0
TSEN2	-1816	-2395.0
TSEN34	3893	-3400.0
TSEN54	-1614	1689.0
TSR1	3117	5039.0
TSR3	-3611	-4069.0
TTC37	1856	3376.0
TXNL4A	-698	625.0
TYW1	2414	455.0
TYW3	4142	-1658.0
TYW5	2090	-843.0
U2AF2	4337	2964.0
U2SURP	4199	-1543.0
UBC	2672	3877.0
UPF1	2528	-2039.0
UPF2	3566	-2231.0
UPF3A	-2545	729.0
UPF3B	1586	-4490.0
URM1	-1818	-3513.0
USP39	1526	1950.0
UTP14A	4777	5328.5
UTP14C	1565	5328.5
UTP15	4137	-396.0
UTP18	3851	2069.0
UTP20	4174	832.0
UTP3	4917	2335.0
UTP6	4779	-1773.0
WBP11	4711	4365.0
WBP4	3659	671.0
WBSCR22	1741	-4222.0
WDR12	1739	-1129.0
WDR18	-812	-3151.0
WDR3	4838	4572.0
WDR33	3143	-994.0
WDR36	4542	2424.0
WDR4	1093	3444.0
WDR43	4883	4985.0
WDR46	3335	3009.0
WDR61	-1148	-234.0
WDR75	3743	3744.0
WDR77	-799	-1323.0
WTAP	4785	1653.0
XAB2	2348	-818.0
XPO1	990	2133.0
XPOT	705	1077.0
XRN1	2636	-1246.0
XRN2	4296	3178.0
YBX1	-681	-2174.0
YWHAB	3680	3468.0
YWHAZ	2019	4919.0
ZBTB8OS	-54	1200.0
ZCCHC11	-2649	1949.0
ZCCHC6	3771	2937.0
ZCRB1	833	-4058.0
ZFP36	-3486	2732.0
ZFP36L1	-4417	2022.0
ZMAT5	1059	-2240.0
ZRSR2	4437	2554.0

---

---

The citric acid (TCA) cycle and respiratory electron transport

The citric acid (TCA) cycle and respiratory electron transport

metric	value
setSize	142
pMANOVA	4.45e-45
p.adjustMANOVA	2.75e-42
s.dist	0.718
s.human	-0.202
s.mouse	-0.689
p.human	3.49e-05
p.mouse	1.02e-45

Top 20 genes

Gene	human	mouse
IDH2	-5216	-4835
D2HGDH	-4890	-5104
PDK2	-5450	-4464
SDHA	-4773	-4748
OGDH	-5268	-4106
SLC16A3	-4751	-4193
ACAD9	-4578	-4327
NDUFB7	-4222	-4592
MDH2	-4361	-4332
NDUFS7	-4871	-3791
NDUFS8	-4325	-4250
NDUFV1	-4226	-4284
CYC1	-4147	-4292
ACO2	-3822	-4534
MPC1	-3681	-4360
SDHC	-3712	-4323
COX8A	-4337	-3691
IDH3G	-4178	-3714
TRAP1	-5265	-2862
NDUFB8	-3020	-4892

Click HERE to show all gene set members

All member genes

	human	mouse
ACAD9	-4578	-4327
ACO2	-3822	-4534
ADHFE1	-4039	-3168
BSG	-2248	-3662
COQ10A	-3553	-3807
COQ10B	4344	1577
COX11	-2860	-2700
COX14	-2772	-4676
COX16	-2259	-2674
COX18	-554	-2459
COX19	3053	2889
COX20	1104	-3676
COX4I1	-2357	-3606
COX5A	-2511	-4214
COX5B	-2559	-4822
COX6A1	2259	-1583
COX6B1	-2231	-3407
COX6C	-18	-3754
COX7B	144	-2853
COX7C	-1495	-3356
COX8A	-4337	-3691
CS	3653	-4328
CYC1	-4147	-4292
D2HGDH	-4890	-5104
DLAT	-1960	-4426
DLD	1187	-4834
DLST	-323	-4762
ECSIT	-2655	-4003
ETFA	3160	-4491
ETFB	-3614	-1903
ETFDH	1884	-4980
FAHD1	-1771	-4836
FH	287	-4146
GLO1	-678	-4289
GSTZ1	-2068	-5077
HAGH	-4509	-2740
IDH2	-5216	-4835
IDH3A	-2155	-4265
IDH3B	-2881	-4194
IDH3G	-4178	-3714
L2HGDH	-262	-2260
LDHA	-3251	-3213
LDHB	-1491	-4379
LRPPRC	1656	-4711
MDH2	-4361	-4332
ME1	1789	-534
ME2	-1789	3649
ME3	4207	-3631
MPC1	-3681	-4360
MPC2	829	-3712
MT-CO1	-3167	-4401
MT-CYB	-1355	-4115
MT-ND1	-353	-4097
MT-ND2	-1120	-4098
MT-ND4	-2086	-3521
MT-ND5	-3244	-3936
MT-ND6	816	-5003
NDUFA1	-737	-4064
NDUFA10	-1955	-4567
NDUFA11	-1033	-3018
NDUFA12	-1315	-3437
NDUFA13	-2253	-4458
NDUFA2	-1290	-3394
NDUFA3	-3805	-3788
NDUFA4	-393	-2605
NDUFA5	534	-4100
NDUFA6	-77	-4563
NDUFA7	-465	-4072
NDUFA8	-602	-3874
NDUFA9	-2868	-3934
NDUFAB1	1151	-3286
NDUFAF1	1175	-4667
NDUFAF2	3504	-3035
NDUFAF3	-3581	-3648
NDUFAF4	3740	-1490
NDUFAF5	29	-2432
NDUFAF6	-2555	-4169
NDUFAF7	2971	-1191
NDUFB10	-3373	-4176
NDUFB11	-2103	-4410
NDUFB2	-3732	-3330
NDUFB3	852	-4452
NDUFB4	-311	-2945
NDUFB5	-2039	-3251
NDUFB6	928	-2670
NDUFB7	-4222	-4592
NDUFB8	-3020	-4892
NDUFB9	-996	-4847
NDUFC1	-664	-3623
NDUFC2	34	-4249
NDUFS1	-1544	-4861
NDUFS2	-3026	-4010
NDUFS3	-3567	-3762
NDUFS4	-1690	-4308
NDUFS5	-1235	-4521
NDUFS6	-1332	-4239
NDUFS7	-4871	-3791
NDUFS8	-4325	-4250
NDUFV1	-4226	-4284
NDUFV3	-2378	-4769
NNT	-3325	-4200
NUBPL	-1541	-1280
OGDH	-5268	-4106
PDHA1	-2405	-4692
PDHB	-133	-4587
PDHX	-126	-4448
PDK1	4600	-3535
PDK2	-5450	-4464
PDK3	4747	5315
PDK4	-712	-4300
PDP1	-2175	-3641
PDP2	-2619	-3350
PDPR	-632	-3822
PPARD	-4213	2330
RXRA	-5519	1619
SCO1	3577	-27
SCO2	-1941	-3526
SDHA	-4773	-4748
SDHB	431	-4408
SDHC	-3712	-4323
SLC16A1	-987	2280
SLC16A3	-4751	-4193
SLC25A14	3834	1677
SLC25A27	-2478	-5079
SUCLA2	1517	-4804
SUCLG1	-31	-4434
SUCLG2	-1167	-4765
SURF1	-1748	-3290
TACO1	651	-4903
TIMMDC1	213	-2918
TMEM126B	1024	1865
TRAP1	-5265	-2862
UCP2	-4949	4253
UCP3	-684	-4891
UQCR10	-3139	-3068
UQCRB	403	-4257
UQCRC1	-3333	-4403
UQCRC2	551	-4650
UQCRFS1	-151	-4321
UQCRH	-1532	-4546
UQCRQ	-1767	-3443
VDAC1	-2909	-4782

---

---

Processing of Capped Intron-Containing Pre-mRNA

Processing of Capped Intron-Containing Pre-mRNA

metric	value
setSize	212
pMANOVA	5.85e-35
p.adjustMANOVA	2.4e-32
s.dist	0.514
s.human	0.5
s.mouse	0.121
p.human	5.18e-36
p.mouse	0.00256

Top 20 genes

Gene	human	mouse
CLP1	4787	5453
PDCD7	4447	5401
NUP98	4235	5486
CDC40	4670	4950
PRPF40A	4797	4800
GTF2F1	4999	4439
ALYREF	5008	4414
NUP54	4508	4751
POLR2A	3861	5366
WBP11	4711	4365
GTF2F2	4067	5047
BUD31	4578	4482
HNRNPU	4229	4805
HSPA8	3674	5419
NUP153	4762	4031
AQR	3952	4831
CRNKL1	4682	3910
SNW1	3618	4892
HNRNPH1	3339	5250
NUP205	4438	3917

Click HERE to show all gene set members

All member genes

	human	mouse
AAAS	-3476	40
ALYREF	5008	4414
AQR	3952	4831
BCAS2	4926	-4687
BUD31	4578	4482
CASC3	9	2673
CCAR1	3856	1341
CD2BP2	2749	-2336
CDC40	4670	4950
CDC5L	2693	369
CHERP	4498	2639
CHTOP	-574	2577
CLP1	4787	5453
CPSF1	-3670	977
CPSF2	-922	-1111
CPSF3	1953	2237
CPSF4	862	4202
CPSF7	407	-1612
CRNKL1	4682	3910
CSTF1	2216	1705
CSTF2	1437	-1058
CSTF2T	2703	4379
CSTF3	-2793	4119
CTNNBL1	-145	476
CWC15	4989	-1054
CWC22	4974	3088
CWC27	1809	-408
DDX23	-645	-2684
DDX39A	3417	-377
DDX39B	984	839
DDX42	2929	4353
DDX46	2094	-964
DDX5	4191	-363
DHX15	2483	4871
DHX16	3981	2235
DHX38	2857	440
DHX9	4151	2848
DNAJC8	4247	-942
EFTUD2	1157	3779
EIF4A3	4491	2615
EIF4E	2892	2481
ELAVL1	2256	1752
FIP1L1	3587	3058
FUS	867	4530
FYTTD1	3374	4804
GCFC2	4300	2962
GLE1	586	-1322
GPKOW	590	4338
GTF2F1	4999	4439
GTF2F2	4067	5047
HNRNPA0	2412	2009
HNRNPA1	3878	4262
HNRNPA2B1	3693	-4286
HNRNPA3	2505	2004
HNRNPC	3406	-403
HNRNPD	4343	3267
HNRNPF	4978	3406
HNRNPH1	3339	5250
HNRNPH2	2261	-2683
HNRNPK	3054	2807
HNRNPL	1064	-948
HNRNPM	4022	-4783
HNRNPR	4406	3418
HNRNPU	4229	4805
HNRNPUL1	2433	-725
HSPA8	3674	5419
ISY1	2662	-330
LSM2	-1347	-1539
LSM3	2210	-2101
LSM4	-2884	-2935
LSM5	2324	-1400
LSM6	-1177	-3681
LSM7	-3487	279
MAGOH	4561	555
MAGOHB	2239	-1880
METTL14	4358	-3888
METTL3	-3688	-708
NCBP1	-1736	4720
NCBP2	4188	-2519
NDC1	1273	-322
NUDT21	3626	432
NUP107	3232	3195
NUP133	889	-2580
NUP153	4762	4031
NUP155	4306	2897
NUP160	3998	2314
NUP188	2117	4593
NUP205	4438	3917
NUP214	3124	1845
NUP35	4571	2515
NUP37	-327	-873
NUP43	4562	193
NUP54	4508	4751
NUP85	3181	227
NUP88	1244	1407
NUP93	-1503	5229
NUP98	4235	5486
NXF1	4992	-1556
NXT1	1765	3075
PCBP1	-3158	-362
PCF11	-1597	-2273
PDCD7	4447	5401
PHF5A	3478	-940
PLRG1	4237	-1621
POLDIP3	-1320	5061
POLR2A	3861	5366
POLR2B	4509	-3401
POLR2C	4529	-4002
POLR2D	1669	3230
POLR2E	-667	148
POLR2G	89	4349
POLR2H	-3927	2213
POLR2I	-154	-2504
POLR2K	2480	-3599
POLR2L	-4314	-1126
PPIE	2144	-1849
PPIH	594	-591
PPIL1	863	2264
PPIL3	4044	-732
PPIL4	3657	-3268
PPWD1	2992	-3786
PQBP1	-379	-3113
PRCC	2656	-830
PRPF19	2441	-4795
PRPF3	4719	3434
PRPF31	1339	3842
PRPF38A	4433	-314
PRPF4	3652	-1807
PRPF40A	4797	4800
PRPF6	684	3858
PRPF8	2926	-1861
PTBP1	3063	4580
PUF60	-2093	174
RAE1	4471	3078
RANBP2	4470	-562
RBM17	2520	872
RBM22	709	1413
RBM5	3930	2323
RNPC3	-3052	2613
RNPS1	681	-2204
SARNP	569	-1380
SART1	759	4758
SEC13	730	938
SEH1L	1085	4110
SF1	4412	2651
SF3A1	3470	3133
SF3A2	2302	714
SF3A3	2871	2458
SF3B1	1067	5041
SF3B2	2676	-3889
SF3B3	3615	4672
SF3B4	4792	3548
SF3B5	1969	817
SLBP	2666	4469
SLU7	4893	2372
SMNDC1	4537	2663
SNRNP200	2626	-3296
SNRNP25	2402	-2311
SNRNP27	2641	-3959
SNRNP35	-2744	-4385
SNRNP40	2967	2772
SNRNP48	4305	-1488
SNRNP70	-267	-2283
SNRPA1	4117	3762
SNRPB	3761	-2577
SNRPB2	4617	677
SNRPC	3677	-3134
SNRPD1	3996	1707
SNRPD2	2043	-2933
SNRPD3	2384	-3590
SNRPE	3421	-1387
SNRPF	3777	-2345
SNRPG	3179	3068
SNRPN	-2163	-1518
SNW1	3618	4892
SRRM1	2285	-2017
SRRM2	-1731	-1080
SRRT	4962	350
SRSF1	1871	-1493
SRSF11	3911	-1990
SRSF3	2586	1697
SRSF4	1929	3741
SRSF5	1997	-3060
SRSF6	1798	2387
SRSF7	3545	2132
SRSF9	3543	2675
SUGP1	-1552	-1352
SYF2	4472	-819
SYMPK	-3207	-1626
TFIP11	5002	2826
THOC1	2868	2971
THOC2	4510	561
THOC3	2831	-3387
THOC5	4842	-589
THOC6	-904	2005
THOC7	-873	-3232
TPR	2984	275
TRA2B	4288	3562
TXNL4A	-698	625
U2AF2	4337	2964
U2SURP	4199	-1543
UPF3B	1586	-4490
USP39	1526	1950
WBP11	4711	4365
WBP4	3659	671
WDR33	3143	-994
WTAP	4785	1653
XAB2	2348	-818
YBX1	-681	-2174
ZCRB1	833	-4058
ZMAT5	1059	-2240
ZRSR2	4437	2554

---

---

Respiratory electron transport

Respiratory electron transport

metric	value
setSize	92
pMANOVA	1.87e-31
p.adjustMANOVA	5.78e-29
s.dist	0.737
s.human	-0.178
s.mouse	-0.715
p.human	0.0033
p.mouse	1.81e-32

Top 20 genes

Gene	human	mouse
SDHA	-4773	-4748
ACAD9	-4578	-4327
NDUFB7	-4222	-4592
NDUFS7	-4871	-3791
NDUFS8	-4325	-4250
NDUFV1	-4226	-4284
CYC1	-4147	-4292
SDHC	-3712	-4323
COX8A	-4337	-3691
TRAP1	-5265	-2862
NDUFB8	-3020	-4892
UQCRC1	-3333	-4403
NDUFA3	-3805	-3788
NDUFB10	-3373	-4176
MT-CO1	-3167	-4401
COQ10A	-3553	-3807
NDUFS3	-3567	-3762
NDUFAF3	-3581	-3648
COX14	-2772	-4676
MT-ND5	-3244	-3936

Click HERE to show all gene set members

All member genes

	human	mouse
ACAD9	-4578	-4327
COQ10A	-3553	-3807
COQ10B	4344	1577
COX11	-2860	-2700
COX14	-2772	-4676
COX16	-2259	-2674
COX18	-554	-2459
COX19	3053	2889
COX20	1104	-3676
COX4I1	-2357	-3606
COX5A	-2511	-4214
COX5B	-2559	-4822
COX6A1	2259	-1583
COX6B1	-2231	-3407
COX6C	-18	-3754
COX7B	144	-2853
COX7C	-1495	-3356
COX8A	-4337	-3691
CYC1	-4147	-4292
ECSIT	-2655	-4003
ETFA	3160	-4491
ETFB	-3614	-1903
ETFDH	1884	-4980
LRPPRC	1656	-4711
MT-CO1	-3167	-4401
MT-CYB	-1355	-4115
MT-ND1	-353	-4097
MT-ND2	-1120	-4098
MT-ND4	-2086	-3521
MT-ND5	-3244	-3936
MT-ND6	816	-5003
NDUFA1	-737	-4064
NDUFA10	-1955	-4567
NDUFA11	-1033	-3018
NDUFA12	-1315	-3437
NDUFA13	-2253	-4458
NDUFA2	-1290	-3394
NDUFA3	-3805	-3788
NDUFA4	-393	-2605
NDUFA5	534	-4100
NDUFA6	-77	-4563
NDUFA7	-465	-4072
NDUFA8	-602	-3874
NDUFA9	-2868	-3934
NDUFAB1	1151	-3286
NDUFAF1	1175	-4667
NDUFAF2	3504	-3035
NDUFAF3	-3581	-3648
NDUFAF4	3740	-1490
NDUFAF5	29	-2432
NDUFAF6	-2555	-4169
NDUFAF7	2971	-1191
NDUFB10	-3373	-4176
NDUFB11	-2103	-4410
NDUFB2	-3732	-3330
NDUFB3	852	-4452
NDUFB4	-311	-2945
NDUFB5	-2039	-3251
NDUFB6	928	-2670
NDUFB7	-4222	-4592
NDUFB8	-3020	-4892
NDUFB9	-996	-4847
NDUFC1	-664	-3623
NDUFC2	34	-4249
NDUFS1	-1544	-4861
NDUFS2	-3026	-4010
NDUFS3	-3567	-3762
NDUFS4	-1690	-4308
NDUFS5	-1235	-4521
NDUFS6	-1332	-4239
NDUFS7	-4871	-3791
NDUFS8	-4325	-4250
NDUFV1	-4226	-4284
NDUFV3	-2378	-4769
NUBPL	-1541	-1280
SCO1	3577	-27
SCO2	-1941	-3526
SDHA	-4773	-4748
SDHB	431	-4408
SDHC	-3712	-4323
SURF1	-1748	-3290
TACO1	651	-4903
TIMMDC1	213	-2918
TMEM126B	1024	1865
TRAP1	-5265	-2862
UQCR10	-3139	-3068
UQCRB	403	-4257
UQCRC1	-3333	-4403
UQCRC2	551	-4650
UQCRFS1	-151	-4321
UQCRH	-1532	-4546
UQCRQ	-1767	-3443

---

---

Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.

Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.

metric	value
setSize	96
pMANOVA	4.84e-31
p.adjustMANOVA	1.19e-28
s.dist	0.717
s.human	-0.176
s.mouse	-0.695
p.human	0.00289
p.mouse	4.96e-32

Top 20 genes

Gene	human	mouse
SDHA	-4773	-4748
ACAD9	-4578	-4327
NDUFB7	-4222	-4592
NDUFS7	-4871	-3791
NDUFS8	-4325	-4250
NDUFV1	-4226	-4284
CYC1	-4147	-4292
SDHC	-3712	-4323
COX8A	-4337	-3691
TRAP1	-5265	-2862
NDUFB8	-3020	-4892
UQCRC1	-3333	-4403
NDUFA3	-3805	-3788
NDUFB10	-3373	-4176
MT-CO1	-3167	-4401
COQ10A	-3553	-3807
NDUFS3	-3567	-3762
NDUFAF3	-3581	-3648
COX14	-2772	-4676
MT-ND5	-3244	-3936

Click HERE to show all gene set members

All member genes

	human	mouse
ACAD9	-4578	-4327
COQ10A	-3553	-3807
COQ10B	4344	1577
COX11	-2860	-2700
COX14	-2772	-4676
COX16	-2259	-2674
COX18	-554	-2459
COX19	3053	2889
COX20	1104	-3676
COX4I1	-2357	-3606
COX5A	-2511	-4214
COX5B	-2559	-4822
COX6A1	2259	-1583
COX6B1	-2231	-3407
COX6C	-18	-3754
COX7B	144	-2853
COX7C	-1495	-3356
COX8A	-4337	-3691
CYC1	-4147	-4292
ECSIT	-2655	-4003
ETFA	3160	-4491
ETFB	-3614	-1903
ETFDH	1884	-4980
LRPPRC	1656	-4711
MT-CO1	-3167	-4401
MT-CYB	-1355	-4115
MT-ND1	-353	-4097
MT-ND2	-1120	-4098
MT-ND4	-2086	-3521
MT-ND5	-3244	-3936
MT-ND6	816	-5003
NDUFA1	-737	-4064
NDUFA10	-1955	-4567
NDUFA11	-1033	-3018
NDUFA12	-1315	-3437
NDUFA13	-2253	-4458
NDUFA2	-1290	-3394
NDUFA3	-3805	-3788
NDUFA4	-393	-2605
NDUFA5	534	-4100
NDUFA6	-77	-4563
NDUFA7	-465	-4072
NDUFA8	-602	-3874
NDUFA9	-2868	-3934
NDUFAB1	1151	-3286
NDUFAF1	1175	-4667
NDUFAF2	3504	-3035
NDUFAF3	-3581	-3648
NDUFAF4	3740	-1490
NDUFAF5	29	-2432
NDUFAF6	-2555	-4169
NDUFAF7	2971	-1191
NDUFB10	-3373	-4176
NDUFB11	-2103	-4410
NDUFB2	-3732	-3330
NDUFB3	852	-4452
NDUFB4	-311	-2945
NDUFB5	-2039	-3251
NDUFB6	928	-2670
NDUFB7	-4222	-4592
NDUFB8	-3020	-4892
NDUFB9	-996	-4847
NDUFC1	-664	-3623
NDUFC2	34	-4249
NDUFS1	-1544	-4861
NDUFS2	-3026	-4010
NDUFS3	-3567	-3762
NDUFS4	-1690	-4308
NDUFS5	-1235	-4521
NDUFS6	-1332	-4239
NDUFS7	-4871	-3791
NDUFS8	-4325	-4250
NDUFV1	-4226	-4284
NDUFV3	-2378	-4769
NUBPL	-1541	-1280
SCO1	3577	-27
SCO2	-1941	-3526
SDHA	-4773	-4748
SDHB	431	-4408
SDHC	-3712	-4323
SLC25A14	3834	1677
SLC25A27	-2478	-5079
SURF1	-1748	-3290
TACO1	651	-4903
TIMMDC1	213	-2918
TMEM126B	1024	1865
TRAP1	-5265	-2862
UCP2	-4949	4253
UCP3	-684	-4891
UQCR10	-3139	-3068
UQCRB	403	-4257
UQCRC1	-3333	-4403
UQCRC2	551	-4650
UQCRFS1	-151	-4321
UQCRH	-1532	-4546
UQCRQ	-1767	-3443

---

---

Mitochondrial translation

Mitochondrial translation

metric	value
setSize	87
pMANOVA	1.8e-30
p.adjustMANOVA	3.54e-28
s.dist	0.687
s.human	0.158
s.mouse	-0.668
p.human	0.0108
p.mouse	4.11e-27

Top 20 genes

Gene	human	mouse
MRPL49	4766	-4287.0
GFM1	4202	-4858.0
GFM2	3817	-5108.0
MRPL44	4401	-4096.0
PTCD3	3483	-5093.0
MRPS22	4380	-3998.0
MRPL9	3433	-4876.0
MRPL16	3084	-4785.0
MRPL18	2996	-4773.0
MRPS35	3107	-4493.0
MRPL3	2973	-4380.0
MRPS31	3506	-3633.0
MRPL19	4079	-3047.0
MRPL15	2470	-4290.0
MRPL22	3353	-2865.0
MRPL30	3497	-2718.5
ERAL1	2608	-3520.0
MRPL11	2096	-4254.0
MRPL42	2106	-4149.0
TSFM	1964	-4406.0

Click HERE to show all gene set members

All member genes

	human	mouse
AURKAIP1	-2308	-3467.0
CHCHD1	-543	-4442.0
DAP3	-463	354.0
ERAL1	2608	-3520.0
GADD45GIP1	-2418	-4820.0
GFM1	4202	-4858.0
GFM2	3817	-5108.0
MRPL1	-1296	-3497.0
MRPL10	-2406	-4655.0
MRPL11	2096	-4254.0
MRPL12	-2657	-3987.0
MRPL13	346	-1087.0
MRPL14	-1702	-2175.0
MRPL15	2470	-4290.0
MRPL16	3084	-4785.0
MRPL17	1930	1614.0
MRPL18	2996	-4773.0
MRPL19	4079	-3047.0
MRPL2	-437	-3027.0
MRPL20	538	-2975.0
MRPL21	1691	-1652.0
MRPL22	3353	-2865.0
MRPL23	-3221	-3820.0
MRPL24	-1884	-4451.0
MRPL27	-1616	-4786.0
MRPL28	-272	-3004.0
MRPL3	2973	-4380.0
MRPL30	3497	-2718.5
MRPL32	3068	3537.0
MRPL34	-2189	-4967.0
MRPL35	810	-3808.0
MRPL36	-560	-3281.0
MRPL37	1607	-4204.0
MRPL38	371	-3781.0
MRPL39	2592	-2566.0
MRPL4	2953	-2793.0
MRPL40	-250	-1725.0
MRPL41	-4898	-4188.0
MRPL42	2106	-4149.0
MRPL43	-1445	-3568.0
MRPL44	4401	-4096.0
MRPL46	1007	-2535.0
MRPL47	3173	-2238.0
MRPL48	-80	-1016.0
MRPL49	4766	-4287.0
MRPL50	3101	-1953.0
MRPL51	-389	-3858.0
MRPL52	-2314	-3091.0
MRPL54	-1999	-2160.0
MRPL55	1089	-4347.0
MRPL9	3433	-4876.0
MRPS10	-3085	-1917.0
MRPS11	283	-4954.0
MRPS12	-146	-4182.0
MRPS14	1795	-4725.0
MRPS15	1875	-4474.0
MRPS16	1205	-3440.0
MRPS17	-131	-2695.0
MRPS18A	469	-4626.0
MRPS18B	-1874	1045.0
MRPS18C	4378	-565.0
MRPS2	1441	-2634.0
MRPS22	4380	-3998.0
MRPS23	1674	-4542.0
MRPS25	-3561	-4702.0
MRPS26	-613	-4421.0
MRPS27	563	-4117.0
MRPS28	1356	-3864.0
MRPS30	3469	-2182.0
MRPS31	3506	-3633.0
MRPS33	152	-2442.0
MRPS34	-3846	-4787.0
MRPS35	3107	-4493.0
MRPS36	-2713	-3917.0
MRPS5	-1175	-4430.0
MRPS6	-4466	1321.0
MRPS7	-1337	-1519.0
MRPS9	1405	-4915.0
MRRF	-2794	77.0
MTFMT	-1455	-3600.0
MTIF2	1804	-3460.0
MTIF3	279	-4638.0
MTRF1L	1519	-4781.0
OXA1L	-2621	-3854.0
PTCD3	3483	-5093.0
TSFM	1964	-4406.0
TUFM	-2588	-4806.0

---

---

Metabolism

Metabolism

metric	value
setSize	1377
pMANOVA	2.01e-30
p.adjustMANOVA	3.54e-28
s.dist	0.209
s.human	-0.115
s.mouse	-0.175
p.human	4.7e-12
p.mouse	9.42e-26

Top 20 genes

Gene	human	mouse
CARNS1	-5545	-5090
PHKG1	-5495	-5107
MGLL	-5374	-5059
AK1	-5327	-5074
GMPR	-5365	-4983
ACSS2	-5297	-5023
MMAB	-5378	-4886
GPT	-5145	-5089
CRAT	-5334	-4863
FITM1	-5314	-4860
PANK1	-5200	-4952
PYGM	-5462	-4695
MPST	-5197	-4899
SLC25A12	-5347	-4761
SLC27A1	-5082	-4976
IDH2	-5216	-4835
GYS1	-5384	-4678
GBA2	-5138	-4888
D2HGDH	-4890	-5104
ACOT11	-5260	-4722

Click HERE to show all gene set members

All member genes

	human	mouse
AAAS	-3476.0	40.0
AACS	-2824.0	5188.0
AASDHPPT	2437.0	-2408.0
ABCA1	1045.0	-2959.0
ABCB7	2119.0	-3680.0
ABCC1	1074.0	2063.0
ABCC3	-265.0	3421.0
ABCC5	1609.0	-4092.0
ABCD1	-5486.0	-3968.0
ABCD4	477.0	-3235.0
ABCG2	-2465.0	5301.0
ABHD10	-834.0	-3238.0
ABHD14B	-3299.0	-4527.0
ABHD3	-81.0	5196.0
ABHD4	-3273.0	2810.0
ABHD5	2522.0	-3351.0
ACAA2	-2330.0	-4889.0
ACACB	-5376.0	-3741.0
ACAD10	-4565.0	-4492.0
ACAD11	421.0	-5042.0
ACAD8	-1259.0	-4572.0
ACAD9	-4578.0	-4327.0
ACADL	-1021.0	-4991.0
ACADM	-1714.0	-4943.0
ACADS	-4663.0	-4266.0
ACADSB	3088.0	-4198.0
ACADVL	-4952.0	-4770.0
ACAT1	470.0	-4325.0
ACAT2	-2653.0	-3794.0
ACBD4	-2075.0	-2337.0
ACBD5	-1208.0	-1600.0
ACER2	-197.0	3788.0
ACER3	-3365.0	4971.0
ACHE	-4785.0	-1898.0
ACLY	-2628.0	4526.0
ACO2	-3822.0	-4534.0
ACOT1	1587.0	-4940.5
ACOT11	-5260.0	-4722.0
ACOT13	-2994.0	-4635.0
ACOT2	-2912.0	-4940.5
ACOT7	-716.0	4137.0
ACOT8	-957.0	-2654.0
ACOT9	478.0	5113.0
ACOX1	3989.0	2503.0
ACOX3	-2027.0	-4032.0
ACP6	-3801.0	-3555.0
ACSF2	-5148.0	1368.0
ACSF3	-4301.0	-3595.0
ACSL1	-3367.0	-4378.0
ACSL3	3465.0	4487.0
ACSL4	481.0	-189.0
ACSS2	-5297.0	-5023.0
ACSS3	1498.0	4654.0
ADA	-2382.0	3820.0
ADAL	625.0	-4562.0
ADCY1	-3780.0	-756.0
ADCY2	-4820.0	-4790.0
ADCY3	338.0	612.0
ADCY5	1967.0	3217.0
ADCY6	-4515.0	-3045.0
ADCY7	-2820.0	3300.0
ADCY9	-4889.0	-2586.0
ADH5	2755.0	-4273.0
ADHFE1	-4039.0	-3168.0
ADI1	-2375.0	-4674.0
ADIPOR1	929.0	87.0
ADIPOR2	3220.0	-842.0
ADK	-1624.0	-4212.0
ADO	3203.0	-280.0
ADPGK	5005.0	5442.0
ADPRM	2616.0	-2042.0
ADRA2A	-4661.0	-686.0
ADSL	-3606.0	-4756.0
ADSS	1913.0	1762.0
ADSSL1	-5209.0	-4213.0
AFMID	-4778.0	-710.0
AGK	-3597.0	-1304.0
AGL	-4967.0	-4710.0
AGPAT1	-1154.0	-1809.0
AGPAT2	-4979.0	-3846.0
AGPAT3	-4732.0	-4580.0
AGPAT4	-4548.0	5313.0
AGPAT5	513.0	1411.0
AGPS	3505.0	2944.0
AGRN	-4903.0	783.0
AGT	-4723.0	-2282.0
AHCY	-4149.0	5056.0
AHCYL1	-3386.0	2570.0
AHR	4872.0	1183.0
AIMP1	1421.0	-2607.0
AIMP2	-2727.0	1101.0
AIP	-707.0	-2446.0
AK1	-5327.0	-5074.0
AK2	-2781.0	-3112.0
AK4	4501.0	-1180.0
AKR1A1	-2363.0	-611.0
AKR1B1	-3280.0	4044.0
AKR1B10	2786.0	-1511.5
AKR1B15	-4492.0	-1511.5
AKT1	-4954.0	1242.0
ALAD	-3855.0	-4632.0
ALAS1	3230.0	-4733.0
ALDH18A1	890.0	5037.0
ALDH1A1	-3063.0	-3653.0
ALDH1L2	872.0	1129.0
ALDH2	-1511.0	-5038.0
ALDH3A2	-71.0	1336.0
ALDH3B1	-4529.0	4664.0
ALDH4A1	-2303.0	-3918.0
ALDH6A1	-1396.0	-4986.0
ALDH7A1	-1797.0	-3733.0
ALDH9A1	2869.0	-3827.0
ALDOA	-5575.0	-3960.0
ALDOC	1379.0	4069.0
AMACR	4160.0	-4700.0
AMD1	4853.0	-1948.0
AMPD1	-5321.0	-4140.0
AMPD2	-3317.0	3919.0
AMPD3	-4286.0	4483.0
ANGPTL4	-739.0	-2615.0
ANKRD1	1306.0	5515.0
AOC2	1475.0	2020.0
AOC3	118.0	2780.0
AOX1	1453.0	-4739.0
APIP	2668.0	1460.0
APOE	-1428.0	-1396.0
APRT	-3384.0	-223.0
ARF1	566.0	3011.0
ARF3	4654.0	2995.0
ARNT	3334.0	1905.0
ARNT2	-2168.0	1220.0
ARNTL	1256.0	2781.0
ARSA	-3312.0	658.0
ARSB	-1001.0	3982.0
ARSG	-3357.0	-265.0
ARSI	-1498.0	2834.0
ARSK	3266.0	-631.0
ARV1	-3314.0	2721.0
ASAH1	-3414.0	5351.0
ASAH2	2603.0	-3200.5
ASL	653.0	3561.0
ASNS	2808.0	3664.0
ASPA	-2360.0	-3239.0
ASRGL1	674.0	-4887.0
ASS1	-5412.0	4389.0
ATIC	7.0	2488.0
AUH	-1294.0	-4152.0
AZIN1	-183.0	5536.0
B3GALNT1	67.0	3120.0
B3GALT1	-3699.0	-2847.0
B3GALT2	-4090.0	527.0
B3GALT4	-2720.0	-3312.0
B3GALT6	-1251.0	2209.0
B3GAT3	-4234.0	-1932.0
B4GALNT1	-3532.0	4914.0
B4GALT1	-1314.0	287.0
B4GALT2	-5041.0	4372.0
B4GALT3	974.0	124.0
B4GALT4	1641.0	-127.0
B4GALT5	-4066.0	2211.0
B4GALT6	2704.0	3176.0
B4GALT7	-4152.0	-3364.0
BCAT1	-3549.0	4562.0
BCAT2	-4182.0	-2507.0
BCHE	364.0	-3179.0
BCKDHB	-4241.0	-2970.0
BCKDK	-4693.0	-4582.0
BDH1	-4435.0	-3405.0
BDH2	-1922.0	1793.0
BGN	-1474.0	4543.0
BLVRA	-1795.0	-2218.0
BLVRB	-5052.0	877.0
BPGM	3356.0	-4515.0
BPHL	-3183.0	-3507.0
BPNT1	4825.0	-3853.0
BSG	-2248.0	-3662.0
BTD	2566.0	2883.0
CA2	4980.0	-2816.0
CA3	-4097.0	-1681.0
CA5B	-72.0	2035.0
CA7	-2940.0	-3983.0
CACNA1A	-1249.0	-1363.0
CACNA1C	-762.0	1596.0
CACNB3	149.0	260.0
CAD	-2572.0	3301.0
CALM1	-4464.0	1071.0
CARM1	-4331.0	-1463.0
CARNS1	-5545.0	-5090.0
CAV1	-646.0	-1312.0
CBR3	297.0	2340.0
CBR4	3854.0	-4600.0
CCNC	4650.0	3631.0
CD320	-2432.0	-1389.0
CD36	-582.0	-4709.0
CD44	837.0	5375.0
CDIPT	2222.0	-4522.0
CDK19	3157.0	-3117.0
CDK8	623.0	-1266.0
CDO1	2038.0	2622.0
CDS1	4830.0	-2241.0
CDS2	-5090.0	3357.0
CEPT1	53.0	83.0
CERK	-4082.0	3655.0
CERS1	-4077.0	-4000.0
CERS2	-2095.0	2775.0
CERS5	2032.0	866.0
CERS6	-4819.0	4527.0
CES2	-5628.0	2539.0
CHAC1	2903.0	-1507.0
CHAC2	3701.0	-1664.0
CHD9	3127.0	1162.0
CHKA	765.0	5327.0
CHP1	-496.0	3915.0
CHPF	-4447.0	3214.0
CHPF2	-2067.0	2242.0
CHPT1	3501.0	-4757.0
CHST11	-184.0	4071.0
CHST12	-1265.0	2414.0
CHST14	-3829.0	2295.0
CHST15	-4700.0	-2560.0
CHST2	2436.0	3710.0
CHST3	-4526.0	3470.0
CHST7	2731.0	-3054.0
CHSY1	3804.0	3498.0
CIAO1	-4183.0	-4746.0
CIAPIN1	4155.0	-4189.0
CIDEC	-4843.0	-2783.0
CKB	-5304.0	4466.0
CKM	-4625.0	-4270.0
CKMT2	-3814.0	-3771.0
CLOCK	-1534.0	3975.0
CMBL	-4971.0	-4607.0
CMPK1	2089.0	4047.0
CNDP2	-2176.0	5209.0
COASY	3072.0	-1176.0
COMT	-5098.0	-4814.0
COQ10A	-3553.0	-3807.0
COQ10B	4344.0	1577.0
COQ2	-1700.0	-3133.0
COQ3	1225.0	-4904.0
COQ5	-3730.0	-4989.0
COQ6	232.0	-4383.0
COQ7	-3047.0	-4433.0
COQ9	-4501.0	-4875.0
COX10	2735.0	-4631.0
COX11	-2860.0	-2700.0
COX14	-2772.0	-4676.0
COX15	571.0	-5005.0
COX16	-2259.0	-2674.0
COX18	-554.0	-2459.0
COX19	3053.0	2889.0
COX20	1104.0	-3676.0
COX4I1	-2357.0	-3606.0
COX5A	-2511.0	-4214.0
COX5B	-2559.0	-4822.0
COX6A1	2259.0	-1583.0
COX6B1	-2231.0	-3407.0
COX6C	-18.0	-3754.0
COX7B	144.0	-2853.0
COX7C	-1495.0	-3356.0
COX8A	-4337.0	-3691.0
CPNE3	1228.0	-837.0
CPOX	-865.0	-3501.0
CPT1A	-357.0	-839.0
CPT2	555.0	-5057.0
CRAT	-5334.0	-4863.0
CREBBP	1506.0	4134.0
CRLS1	-1542.0	-2894.0
CROT	3694.0	4862.0
CRYL1	-3923.0	-310.0
CS	3653.0	-4328.0
CSAD	-2141.0	-1906.0
CSGALNACT1	-205.0	89.0
CSGALNACT2	1507.0	5133.0
CSNK1G2	-1933.0	-3089.0
CSNK2A1	1796.0	-2551.0
CSNK2A2	2123.0	2667.0
CSNK2B	1917.0	-1746.0
CSPG4	-5621.0	2625.0
CTH	4099.0	-1006.0
CTPS1	3837.0	4515.0
CTPS2	-2992.0	-3016.0
CTSA	-3537.0	-3391.0
CYB5A	-1123.0	-3119.0
CYB5B	621.0	-4067.0
CYB5R3	-5395.0	3844.0
CYC1	-4147.0	-4292.0
CYGB	-3091.0	118.0
CYP26B1	-756.0	811.0
CYP27A1	-4508.0	-5091.0
CYP2E1	-1403.0	-1494.0
CYP2J2	-5037.0	-3267.0
CYP2U1	-3305.0	-3638.0
CYP39A1	1668.0	-2309.0
CYP4V2	-2707.0	73.0
CYP51A1	-1716.0	5305.0
D2HGDH	-4890.0	-5104.0
DBI	-2859.0	-619.0
DBT	2001.0	5426.0
DCK	-511.0	4139.0
DCN	-1048.0	102.0
DCTD	-3586.0	2127.0
DCTPP1	2817.0	-2688.0
DCXR	-3844.0	-970.0
DDAH1	4850.0	3189.0
DDAH2	-4544.0	424.0
DDHD1	1781.0	3760.0
DDHD2	185.0	-2686.0
DDO	-3779.0	-4874.0
DECR1	-2617.0	-4927.0
DECR2	-2311.0	1855.0
DEGS1	-2228.0	4156.0
DERA	3823.0	2342.0
DGAT1	-2804.0	-766.0
DGAT2	387.0	-4703.0
DGUOK	2349.0	-3307.0
DHCR24	3807.0	4148.0
DHCR7	-5099.0	2597.0
DHFR	-3638.0	2914.5
DHODH	1292.0	-4914.0
DHRS7B	-5012.0	-4519.0
DHTKD1	-419.0	-3519.0
DIO2	-666.0	3937.0
DLAT	-1960.0	-4426.0
DLD	1187.0	-4834.0
DLST	-323.0	-4762.0
DNM2	-1149.0	218.0
DNPH1	-2705.0	357.0
DPYD	1236.0	-1765.0
DSE	3382.0	3377.0
DSEL	4232.0	2744.0
DTYMK	-1277.0	-224.0
DUT	-592.0	-2679.0
EBP	1444.0	929.0
ECHS1	-3895.0	-4648.0
ECI1	-3975.0	-4524.0
ECI2	-4454.0	-4351.0
ECSIT	-2655.0	-4003.0
EEF1E1	2843.0	3832.0
EEFSEC	-4387.0	955.0
EHHADH	-1005.0	-906.0
ELOVL1	-3641.0	5078.0
ELOVL5	4908.0	602.0
ELOVL6	1603.0	4205.0
ENO1	-4083.0	2108.0
ENO2	-2024.0	606.0
ENO3	-4671.0	-3886.0
ENOPH1	1391.0	6.0
ENPP1	4114.0	4941.0
ENPP2	3080.0	-3545.0
ENPP3	-537.0	569.0
ENTPD5	-4035.0	-459.0
ENTPD6	-4382.0	-253.0
ENTPD7	-2365.0	5199.0
EP300	3403.0	2309.0
EPHX1	-5101.0	1231.0
EPHX2	-2227.0	-4973.0
EPM2A	-579.0	-4807.0
ERCC2	824.0	4319.0
ESD	953.0	1680.0
ESRRA	-4570.0	-4658.0
ESYT1	-5390.0	5066.0
ESYT2	-3789.0	4203.0
ETFA	3160.0	-4491.0
ETFB	-3614.0	-1903.0
ETFDH	1884.0	-4980.0
ETHE1	-1851.0	-1092.0
ETNK1	3905.0	-1974.0
EXT1	3887.0	5418.0
EXT2	2074.0	3224.0
FABP3	-5075.0	2371.0
FABP5	-338.0	587.0
FADS1	-4196.0	4323.0
FADS2	-4594.0	2686.0
FAH	-3942.0	-834.0
FAHD1	-1771.0	-4836.0
FAM120B	-1675.0	-1552.0
FAR1	3520.0	4294.0
FASN	-4976.0	4216.0
FAU	2272.0	2649.0
FBP2	-3323.0	-4689.0
FDFT1	-4290.0	-4850.0
FDPS	-3811.0	236.0
FDX1	2337.0	-3473.0
FDXR	-4136.0	-4316.0
FECH	-3768.0	-4627.0
FH	287.0	-4146.0
FHL2	-4462.0	4582.0
FIG4	-2187.0	2943.0
FITM1	-5314.0	-4860.0
FITM2	-1820.0	-4344.0
FLAD1	3295.0	-5036.0
FLVCR1	1431.0	-2760.0
FMOD	-329.0	1647.0
FPGS	-5408.0	-542.0
FUT10	2544.0	943.0
FUT11	-3756.0	-774.0
FXN	-2179.0	-3293.0
G0S2	-5182.0	-4324.0
G6PC3	-3066.0	-1440.0
G6PD	579.0	5116.0
GAA	-5001.0	-2492.0
GADL1	-5127.0	-767.0
GALC	1050.0	-3828.0
GALE	-4804.0	2476.0
GALK1	-3470.0	1879.0
GALT	-2687.0	-4691.0
GAMT	-5400.0	-2080.0
GART	3329.0	-1128.0
GATM	-2803.0	-730.0
GBA	-1680.0	2061.0
GBA2	-5138.0	-4888.0
GBE1	532.0	-4207.0
GCAT	-3849.0	-1170.0
GCDH	-2239.0	-4461.0
GCH1	358.0	5291.0
GCLC	2502.0	4485.0
GCLM	-818.0	-221.0
GCSH	-140.0	-2869.0
GDE1	-1579.0	-2250.0
GDPD1	339.0	1652.0
GDPD3	-2758.0	1786.0
GDPD5	-5469.0	-2261.0
GGCT	-1031.0	-1879.0
GGPS1	2567.0	988.0
GGT5	-954.0	-2472.0
GGT7	-2763.0	3951.0
GK	1198.0	3985.0
GLA	3418.0	-1236.0
GLB1	-2244.0	2071.0
GLB1L	-1827.0	400.0
GLCE	3967.0	4678.0
GLO1	-678.0	-4289.0
GLRX	1619.0	-2252.0
GLRX5	-1282.0	-4074.0
GLS	4937.0	1394.0
GLTP	486.0	3307.0
GLUD1	-360.0	-2088.0
GLUL	2197.0	5256.0
GLYCTK	1312.0	-2517.0
GM2A	-1169.0	1984.0
GMPR	-5365.0	-4983.0
GMPR2	-1133.0	-1466.0
GMPS	3153.0	2422.0
GNA11	-1689.0	2150.0
GNAI1	183.0	1373.0
GNAI2	800.0	2142.0
GNAQ	4906.0	4533.0
GNAS	-3163.0	-1742.0
GNB1	177.0	5374.0
GNB2	-3870.0	1232.0
GNB3	-3272.0	-676.0
GNB4	-3491.0	1634.0
GNB5	879.0	-2818.0
GNG11	4695.0	-4457.0
GNG12	612.0	604.0
GNG2	802.0	-2139.0
GNG5	415.0	-3220.0
GNG7	-2742.0	-4220.0
GNPAT	-1893.0	-3964.0
GNPDA1	-244.0	-1167.0
GNPDA2	685.0	-1114.0
GNS	101.0	639.0
GOT1	-3758.0	-3482.0
GOT2	-3704.0	-4606.0
GPAM	1132.0	-5046.0
GPC1	-5269.0	-1574.0
GPC4	-5170.0	-4334.0
GPC6	-2385.0	1959.0
GPCPD1	-3490.0	-2626.0
GPD1	-5525.0	-2317.0
GPD1L	-4058.0	-4199.0
GPD2	1922.0	-880.0
GPHN	-1543.0	-3163.0
GPI	-5210.0	-4750.0
GPS2	2002.0	-25.0
GPT	-5145.0	-5089.0
GPT2	2762.0	-4114.0
GPX1	-4411.0	-553.0
GPX4	-3706.0	-4293.0
GRHPR	-4730.0	-4938.0
GSR	-2148.0	848.0
GSS	-4919.0	4255.0
GSTK1	-4345.0	-4224.0
GSTM2	-4720.0	299.0
GSTM3	-2929.0	3358.0
GSTM4	-5020.0	-3344.0
GSTO1	-2055.0	-3769.0
GSTT2B	-3100.0	-4288.0
GSTZ1	-2068.0	-5077.0
GUK1	-1482.0	-3434.0
GUSB	1923.0	4620.0
GYG1	-3875.0	4407.0
GYS1	-5384.0	-4678.0
HACL1	4520.0	-3057.0
HADH	-2786.0	-5075.0
HADHA	-3202.0	-4418.0
HADHB	-2035.0	-4747.0
HAGH	-4509.0	-2740.0
HAS3	-238.0	-614.0
HDAC3	-178.0	-2363.0
HELZ2	-2454.0	1374.0
HEXA	-221.0	1391.0
HEXB	753.0	1511.0
HIBADH	-4032.0	-4229.0
HIBCH	488.0	-4841.0
HILPDA	972.0	-124.0
HK1	-4205.0	3384.0
HK2	4651.0	-4039.0
HLCS	-758.0	-733.0
HMBS	-3958.0	-3897.0
HMGCL	-4130.0	-3323.0
HMGCR	971.0	4993.0
HMGCS1	-971.0	-414.0
HMOX1	-2843.0	4573.0
HMOX2	-687.0	-3441.0
HNMT	-4076.0	-4910.0
HPGD	1681.0	-261.0
HPRT1	1069.0	3299.0
HS2ST1	1682.0	4399.0
HS3ST5	-1643.0	-2888.0
HS6ST1	-2524.0	5378.0
HS6ST2	-4550.0	499.0
HSCB	-134.0	-1814.0
HSD11B1	-1964.0	-3260.0
HSD17B10	-1193.0	-1970.0
HSD17B11	1302.0	-1900.0
HSD17B12	2118.0	5293.0
HSD17B4	689.0	-4557.0
HSD17B7	1183.0	2601.0
HSD3B7	-4371.0	1184.0
HSP90AA1	3656.0	5525.0
HSP90AB1	-639.0	5203.0
HSPG2	-5351.0	1532.0
HYAL1	-3845.0	2439.0
HYAL2	-3575.0	3289.0
HYKK	-1791.0	-3107.0
IDH1	1160.0	-4779.0
IDH2	-5216.0	-4835.0
IDH3A	-2155.0	-4265.0
IDH3B	-2881.0	-4194.0
IDH3G	-4178.0	-3714.0
IDI1	230.0	126.0
IDS	-2473.0	3298.0
IDUA	-3866.0	-4839.0
IMPA1	3774.0	5135.0
IMPA2	-3509.0	-4438.0
IMPDH1	-827.0	3626.0
IMPDH2	822.0	-801.0
INPP1	-2482.0	654.0
INPP4A	793.0	-1029.0
INPP4B	-4822.0	2562.0
INPP5A	-4116.0	1715.0
INPP5B	2499.0	3885.0
INPP5D	-2433.0	4627.0
INPP5E	-1642.0	-4413.0
INPP5F	2723.0	2632.0
INPP5J	-2610.0	-615.0
INPP5K	-907.0	-4999.0
INPPL1	-5220.0	-2663.0
INSIG1	-3105.0	4213.0
INSIG2	767.0	-3880.0
IP6K1	-1181.0	-2599.0
IP6K2	3404.0	-226.0
IP6K3	-5500.0	-1526.0
IPMK	3766.0	2875.0
IPPK	1454.0	2025.0
IQGAP1	-415.0	4295.0
ISCA1	2917.0	-4001.0
ISCA2	-2735.0	-5030.0
ISCU	-3113.0	-2973.0
ISYNA1	-5409.0	-795.0
ITPA	-3760.0	-1741.0
ITPK1	-2911.0	3927.0
ITPKB	-4873.0	-3412.0
ITPKC	-5243.0	3393.0
ITPR1	4903.0	1106.0
ITPR2	1242.0	53.0
ITPR3	-3631.0	-2403.0
IVD	-4805.0	-4233.0
KCNB1	-5117.0	-989.0
KCNJ11	-5488.0	339.0
KDSR	3114.0	2573.0
KERA	526.0	1904.0
KHK	4875.0	-4006.0
KPNB1	3619.0	4744.0
L2HGDH	-262.0	-2260.0
LBR	2244.0	-878.0
LCLAT1	3962.0	4343.0
LDHA	-3251.0	-3213.0
LDHB	-1491.0	-4379.0
LDLR	-3949.0	5260.0
LGMN	4834.0	651.0
LHPP	-3082.0	-4375.0
LIAS	-1131.0	-4063.0
LIPE	-1863.0	-3990.0
LIPT1	3416.0	5104.0
LIPT2	299.0	-2164.0
LMBRD1	310.0	-2203.0
LPCAT1	-1659.0	2360.0
LPCAT3	4224.0	-3906.0
LPCAT4	-1185.0	3804.0
LPGAT1	1940.0	4158.0
LPIN1	-2877.0	-4450.0
LPIN2	3569.0	3805.0
LPIN3	-1052.0	2283.0
LRP1	-3652.0	3049.0
LRP10	-3203.0	1445.0
LRP12	4543.0	5259.0
LRPPRC	1656.0	-4711.0
LSS	-5278.0	5001.0
LTA4H	1584.0	2751.0
LUM	-1839.0	2563.0
LYPLA1	1177.0	-3204.0
LYRM4	2696.0	2758.0
MAN2B1	-3000.0	564.0
MAN2B2	-155.0	1673.0
MAN2C1	-4801.0	-3010.0
MANBA	-1928.0	-2624.0
MAOA	-96.0	3828.0
MAPKAPK2	-2489.0	-1825.0
MAT2A	-2353.0	-529.0
MAT2B	3692.0	-4803.0
MBOAT1	3920.0	5216.0
MBOAT2	-83.0	2368.0
MBOAT7	502.0	4112.0
MBTPS1	-3834.0	39.0
MBTPS2	3778.0	-3334.0
MCAT	-628.0	-4342.0
MCCC1	4013.0	-4623.0
MCCC2	2204.0	-4951.0
MCEE	-816.0	-4855.0
MDH1	-1091.0	-4150.0
MDH2	-4361.0	-4332.0
ME1	1789.0	-534.0
ME2	-1789.0	3649.0
ME3	4207.0	-3631.0
MECR	-3190.0	-3135.0
MED1	4772.0	358.0
MED10	4087.0	2486.0
MED11	-2050.0	1286.0
MED12	-2130.0	-467.0
MED13	4601.0	5355.0
MED13L	2680.0	3953.0
MED14	2781.0	-2531.0
MED15	1233.0	5257.0
MED16	-2476.0	-4399.0
MED17	4255.0	2011.0
MED18	3737.0	-173.0
MED19	3689.0	3193.0
MED20	3604.0	-1597.0
MED21	3526.0	889.0
MED22	-2885.0	956.0
MED23	3909.0	2920.0
MED24	-4786.0	-3269.0
MED25	2948.0	-1517.0
MED26	4038.0	2729.0
MED27	1227.0	3367.0
MED28	1120.0	-2368.0
MED29	3193.0	-1040.0
MED30	2307.0	-538.0
MED31	4638.0	-2680.0
MED4	4026.0	2219.0
MED6	4813.0	-1254.0
MED7	4316.0	1176.0
MED8	4163.0	-2286.0
MED9	-227.0	-259.0
MGLL	-5374.0	-5059.0
MGST1	427.0	-2928.0
MGST3	-3048.0	-2582.0
MID1IP1	2058.0	-2839.0
MINPP1	2622.0	3325.0
MLX	-346.0	-788.0
MLXIPL	-3136.0	-2621.0
MLYCD	-2169.0	-5081.0
MMAA	2798.0	-4294.0
MMAB	-5378.0	-4886.0
MMACHC	1931.0	-3818.0
MMADHC	3242.0	-3483.0
MMS19	-1079.0	1304.0
MOCOS	958.0	4000.0
MOCS1	-3691.0	-3565.0
MOCS2	-384.0	-4726.0
MOCS3	2496.0	-2057.0
MORC2	4923.0	-3070.0
MPC1	-3681.0	-4360.0
MPC2	829.0	-3712.0
MPST	-5197.0	-4899.0
MRI1	-1694.0	-3266.0
MSMO1	-3763.0	4845.0
MT-CO1	-3167.0	-4401.0
MT-CYB	-1355.0	-4115.0
MT-ND1	-353.0	-4097.0
MT-ND2	-1120.0	-4098.0
MT-ND4	-2086.0	-3521.0
MT-ND5	-3244.0	-3936.0
MT-ND6	816.0	-5003.0
MTAP	-2515.0	2769.0
MTF1	4744.0	3433.0
MTHFD1	-2873.0	-4237.0
MTHFD2	3294.0	5454.0
MTHFD2L	1711.0	84.0
MTHFR	-5536.0	3225.0
MTHFS	-39.0	-246.0
MTM1	-1860.0	-567.0
MTMR1	1919.0	-1485.0
MTMR10	-2009.0	3050.0
MTMR12	1044.0	3580.0
MTMR14	3326.0	250.0
MTMR2	-2470.0	2041.0
MTMR3	-817.0	418.0
MTMR4	3209.0	4765.0
MTMR6	97.0	-147.0
MTMR9	2885.0	-1194.0
MTR	2939.0	-3632.0
MTRR	2177.0	2936.0
MVD	-4915.0	4850.0
MVK	-5582.0	709.0
N6AMT1	-2374.0	-2711.0
NADK	-2052.0	4309.0
NADK2	-1735.0	-3459.0
NADSYN1	-3738.0	-3092.0
NAGLU	-3708.0	-605.0
NAMPT	2093.0	166.5
NAT1	4478.0	4030.0
NCOA1	2628.0	708.0
NCOA2	146.0	558.0
NCOA3	4584.0	1433.0
NCOA6	-3402.0	1302.0
NCOR1	2625.0	-1011.0
NCOR2	-5167.0	-143.0
NDC1	1273.0	-322.0
NDOR1	-87.0	-2413.0
NDST1	-3078.0	666.0
NDUFA1	-737.0	-4064.0
NDUFA10	-1955.0	-4567.0
NDUFA11	-1033.0	-3018.0
NDUFA12	-1315.0	-3437.0
NDUFA13	-2253.0	-4458.0
NDUFA2	-1290.0	-3394.0
NDUFA3	-3805.0	-3788.0
NDUFA4	-393.0	-2605.0
NDUFA5	534.0	-4100.0
NDUFA6	-77.0	-4563.0
NDUFA7	-465.0	-4072.0
NDUFA8	-602.0	-3874.0
NDUFA9	-2868.0	-3934.0
NDUFAB1	1151.0	-3286.0
NDUFAF1	1175.0	-4667.0
NDUFAF2	3504.0	-3035.0
NDUFAF3	-3581.0	-3648.0
NDUFAF4	3740.0	-1490.0
NDUFAF5	29.0	-2432.0
NDUFAF6	-2555.0	-4169.0
NDUFAF7	2971.0	-1191.0
NDUFB10	-3373.0	-4176.0
NDUFB11	-2103.0	-4410.0
NDUFB2	-3732.0	-3330.0
NDUFB3	852.0	-4452.0
NDUFB4	-311.0	-2945.0
NDUFB5	-2039.0	-3251.0
NDUFB6	928.0	-2670.0
NDUFB7	-4222.0	-4592.0
NDUFB8	-3020.0	-4892.0
NDUFB9	-996.0	-4847.0
NDUFC1	-664.0	-3623.0
NDUFC2	34.0	-4249.0
NDUFS1	-1544.0	-4861.0
NDUFS2	-3026.0	-4010.0
NDUFS3	-3567.0	-3762.0
NDUFS4	-1690.0	-4308.0
NDUFS5	-1235.0	-4521.0
NDUFS6	-1332.0	-4239.0
NDUFS7	-4871.0	-3791.0
NDUFS8	-4325.0	-4250.0
NDUFV1	-4226.0	-4284.0
NDUFV3	-2378.0	-4769.0
NEU1	1863.0	2997.0
NEU3	2532.0	-4078.0
NFS1	-223.0	-4912.0
NFYA	4965.0	4520.0
NFYB	1632.0	-4319.0
NFYC	-1444.0	-2678.0
NHLRC1	-3454.0	3765.0
NME1	-2381.0	-3157.0
NME4	-4099.0	-1123.0
NMNAT1	412.0	-4763.0
NMNAT3	-378.0	-5006.0
NMRAL1	1147.0	-1702.0
NMRK1	-952.0	-713.0
NMRK2	-5134.0	-2132.0
NNMT	-1077.0	3466.0
NNT	-3325.0	-4200.0
NOSIP	-2487.0	-2931.0
NPAS2	-113.0	2216.0
NQO1	2413.0	151.0
NQO2	-4228.0	-4825.0
NR1D1	-5185.0	-383.0
NR1H2	2288.0	2282.0
NR1H3	-3630.0	-3340.0
NRF1	3039.0	4595.0
NSDHL	-744.0	1007.0
NT5C	-2948.0	2504.0
NT5C1A	-4696.0	-1492.0
NT5C2	-3541.0	5381.0
NT5C3A	4203.0	1666.0
NT5E	1998.0	1133.0
NT5M	-4287.0	-4172.0
NUBP1	-98.0	4313.0
NUBP2	392.0	-45.0
NUBPL	-1541.0	-1280.0
NUDT1	-381.0	-2788.0
NUDT10	4564.0	285.5
NUDT11	4565.0	285.5
NUDT12	1433.0	-1930.0
NUDT13	-3450.0	-3678.0
NUDT15	2604.0	-1355.0
NUDT16	-4497.0	-68.0
NUDT19	-2286.0	-2667.0
NUDT3	-1599.0	-4171.0
NUDT4	-2656.0	5488.0
NUDT5	3490.0	867.0
NUDT7	-3378.0	-4518.0
NUDT9	-1871.0	-3338.0
NUP107	3232.0	3195.0
NUP133	889.0	-2580.0
NUP153	4762.0	4031.0
NUP155	4306.0	2897.0
NUP160	3998.0	2314.0
NUP188	2117.0	4593.0
NUP205	4438.0	3917.0
NUP214	3124.0	1845.0
NUP35	4571.0	2515.0
NUP37	-327.0	-873.0
NUP43	4562.0	193.0
NUP54	4508.0	4751.0
NUP85	3181.0	227.0
NUP88	1244.0	1407.0
NUP93	-1503.0	5229.0
NUP98	4235.0	5486.0
OAT	393.0	-4498.0
OAZ1	-2480.0	-1682.0
OAZ2	-3421.0	-4082.0
OCRL	2293.0	3260.0
ODC1	5000.0	4335.0
OGDH	-5268.0	-4106.0
OGN	1004.0	-859.0
OPLAH	-2761.0	-4310.0
ORMDL1	3910.0	-3349.0
ORMDL2	3463.0	948.0
ORMDL3	893.0	3754.0
OSBP	2398.0	131.0
OSBPL10	4.0	2164.0
OSBPL1A	-2961.0	-5076.0
OSBPL2	-4737.0	-3849.0
OSBPL3	-3505.0	4695.0
OSBPL5	-4860.0	2900.0
OSBPL6	4592.0	-126.0
OSBPL7	-5587.0	1267.0
OSBPL8	4881.0	4833.0
OSBPL9	3722.0	-4873.0
OXCT1	-106.0	-3711.0
PAICS	-743.0	-4987.0
PANK1	-5200.0	-4952.0
PANK2	2471.0	2728.0
PANK3	1575.0	4711.0
PANK4	-3473.0	-4977.0
PAOX	223.0	873.0
PAPSS1	4253.0	3460.0
PAPSS2	1717.0	-452.0
PARP10	-4978.0	-2487.0
PARP14	-1721.0	-1772.0
PARP16	-79.0	-3339.0
PARP4	-4440.0	1808.0
PARP6	448.0	-97.0
PARP8	4194.0	1235.0
PARP9	-3114.0	-1883.0
PC	-5226.0	851.0
PCCA	-2597.0	-4409.0
PCCB	-165.0	-4900.0
PCK2	-2317.0	969.0
PCTP	-322.0	-3225.0
PCYT1A	-2527.0	-2111.0
PCYT2	-4448.0	-4081.0
PDHA1	-2405.0	-4692.0
PDHB	-133.0	-4587.0
PDHX	-126.0	-4448.0
PDK1	4600.0	-3535.0
PDK2	-5450.0	-4464.0
PDK3	4747.0	5315.0
PDK4	-712.0	-4300.0
PDP1	-2175.0	-3641.0
PDP2	-2619.0	-3350.0
PDPR	-632.0	-3822.0
PDSS1	4374.0	-3608.0
PDSS2	998.0	-4679.0
PDXK	-4690.0	-936.0
PDZD11	1678.0	-2562.0
PECR	-1213.0	-2572.0
PEMT	-3689.0	-465.0
PEX11A	934.0	-4813.0
PFAS	-623.0	-4560.0
PFKFB1	-3021.0	-4971.0
PFKFB2	-4240.0	-2209.0
PFKFB3	2321.0	-4053.0
PFKFB4	-1766.0	2454.0
PFKL	-4966.0	4614.0
PFKM	-4574.0	-4576.0
PFKP	-2129.0	4639.0
PGAM2	-5379.0	-4444.0
PGD	-199.0	4346.0
PGK1	-1414.0	-3278.0
PGLS	-2896.0	-2269.0
PGM1	-4270.0	-4828.0
PGM2	-561.0	4131.0
PGM2L1	4913.0	-2553.0
PGP	-2575.0	-4181.0
PGS1	-795.0	885.0
PHGDH	-232.0	3669.0
PHKA1	-3965.0	-2457.0
PHKA2	-3873.0	-3172.0
PHKB	-3289.0	-4539.0
PHKG1	-5495.0	-5107.0
PHKG2	-225.0	4281.0
PHOSPHO1	-1466.0	-4774.0
PHYH	-4170.0	-4330.0
PHYKPL	-5050.0	-3365.0
PI4K2A	1510.0	5004.0
PI4K2B	1087.0	2846.0
PI4KA	-2484.0	3330.0
PI4KB	1642.0	3713.0
PIAS4	342.0	-629.0
PIK3C2A	2851.0	1567.0
PIK3C2B	-5561.0	1405.0
PIK3C3	3439.0	-1596.0
PIK3CA	365.0	4218.0
PIK3CB	2760.0	5125.0
PIK3CD	-4322.0	-2306.0
PIK3R1	2896.0	-813.0
PIK3R3	3188.0	3545.0
PIK3R4	3839.0	-3124.0
PIKFYVE	4791.0	3146.0
PIP4K2A	4108.0	4105.0
PIP4K2C	2827.0	4009.0
PIP5K1A	4918.0	3132.0
PIP5K1C	-1917.0	2945.0
PISD	15.0	1297.0
PITPNB	3953.0	4104.0
PITPNM1	-4916.0	1684.0
PITPNM2	-5437.0	-442.0
PKM	-4231.0	-3432.0
PLA1A	-1379.0	-1195.0
PLA2G12A	2265.0	-3480.0
PLA2G15	-5459.0	-3289.0
PLA2G4A	603.0	4806.0
PLA2G6	-3913.0	-2025.0
PLA2R1	66.0	-1300.0
PLB1	-3857.0	-1943.0
PLBD1	1550.0	-4797.0
PLCB1	-1580.0	-2084.0
PLCB3	-3863.0	993.0
PLCB4	-4274.0	-2681.0
PLCD1	-3494.0	-264.0
PLCD3	-5573.0	1533.0
PLCD4	-4964.0	-4302.0
PLCE1	-4858.0	765.0
PLCG1	-3955.0	-1787.0
PLD1	55.0	46.0
PLD2	-60.0	-498.0
PLD3	-5217.0	18.0
PLEKHA1	-4791.0	5443.0
PLEKHA2	-5155.0	-2483.0
PLEKHA3	3763.0	1457.0
PLEKHA4	-1772.0	3062.0
PLEKHA5	3159.0	325.0
PLEKHA6	-5554.0	-2893.0
PLEKHA8	2098.0	1736.0
PLIN2	-4079.0	3266.0
PLIN3	-5023.0	-4893.0
PMVK	-2891.0	-4984.0
PNP	5019.5	4921.0
PNPLA2	-5011.0	-4643.0
PNPLA3	-2170.0	-4942.0
PNPLA6	989.0	-1169.0
PNPLA7	-4601.0	-5112.0
PNPLA8	2977.0	-3540.0
PNPO	-3095.0	-3311.0
PODXL2	-4588.0	-3974.0
POLD1	-3218.0	-1289.0
PON2	-2005.0	183.0
POR	-5507.0	3701.0
PPA1	1522.0	-1816.0
PPA2	-163.0	-3735.0
PPARA	-4997.0	-2863.0
PPARD	-4213.0	2330.0
PPARG	-1621.0	-2602.0
PPARGC1A	-4212.0	-4916.0
PPARGC1B	-5257.0	-2496.0
PPAT	2768.0	-1127.0
PPCDC	-3702.0	-4309.0
PPCS	3010.0	-4057.0
PPIP5K1	-2557.0	-3898.0
PPIP5K2	3204.0	1340.0
PPM1K	2278.0	-4721.0
PPM1L	-5249.0	-4291.0
PPOX	-3785.0	-3297.0
PPP1CA	-4408.0	-15.0
PPP1CB	-1374.0	-3335.0
PPP1CC	4081.0	-1627.0
PPP1R3C	-5015.0	4128.0
PPP2CA	4482.0	1672.0
PPP2CB	2458.0	2352.0
PPP2R1A	-4013.0	-681.0
PPP2R1B	3028.0	3194.0
PPP2R5D	-3449.0	-620.0
PPT1	2553.0	-643.0
PPT2	-3952.0	-3594.0
PRKAA2	-3219.0	-2647.0
PRKAB2	-2332.0	-3109.0
PRKACA	-4691.0	-4303.0
PRKACB	-2659.0	-360.0
PRKAG2	-3237.0	502.0
PRKAR1A	-3106.0	203.0
PRKAR1B	-2442.0	3659.0
PRKAR2A	-2664.0	1823.0
PRKAR2B	3460.0	1006.0
PRKCA	-2938.0	1125.0
PRKD1	-5136.0	352.0
PRKD2	635.0	-2852.0
PRKD3	719.0	4310.0
PRODH	-3891.0	-4488.0
PRPS1	3067.0	3811.0
PRPS2	3570.0	1432.0
PSAP	-2247.0	-4177.0
PSAT1	2572.0	5277.0
PSMA1	2820.0	4043.0
PSMA3	3434.0	-1035.0
PSMA4	769.0	-1962.0
PSMA6	2199.0	-1657.0
PSMA7	-2980.0	-1038.0
PSMB1	954.0	-1037.0
PSMB10	-1800.0	-831.0
PSMB2	618.0	-67.0
PSMB4	-235.0	-559.0
PSMB5	-4113.0	-2597.0
PSMB6	-793.0	-1795.0
PSMB7	-831.0	-2699.0
PSMB8	-675.0	-2510.0
PSMB9	-1611.0	-3558.0
PSMC1	449.0	1146.0
PSMC2	-1311.0	3386.0
PSMC3	-2439.0	-1846.0
PSMC4	2724.0	-205.0
PSMC5	1212.0	-1680.0
PSMC6	-2520.0	3114.0
PSMD1	2619.0	3210.0
PSMD10	-1227.0	361.0
PSMD11	995.0	5504.0
PSMD12	3831.0	-462.0
PSMD13	821.0	532.0
PSMD14	-635.0	3746.0
PSMD2	-713.0	741.0
PSMD3	-3343.0	-354.0
PSMD4	-214.0	968.0
PSMD5	1807.0	4479.0
PSMD6	3537.0	-3784.0
PSMD7	-2329.0	410.0
PSMD8	-3171.0	4292.0
PSMD9	4204.0	-3586.0
PSME1	-2771.0	-2861.0
PSME2	-4085.0	-41.0
PSME3	3333.0	491.0
PSME4	1960.0	2319.0
PSMF1	683.0	-1768.0
PSPH	-872.0	-903.0
PSTK	2140.0	-4467.0
PTDSS1	-325.0	1303.0
PTDSS2	-4414.0	-2314.0
PTEN	2797.0	4830.0
PTGES	-495.0	-2335.0
PTGES2	-2699.0	-3773.0
PTGES3	1328.0	2246.0
PTGIS	-1921.0	2930.0
PTGR1	3646.0	3810.0
PTGR2	-1055.0	-5011.0
PTGS1	-854.0	3113.0
PTPN13	4200.0	1720.0
PTS	1355.0	-3248.0
PXMP2	-1741.0	-4990.0
PYCR1	-5006.0	4020.0
PYCR2	181.0	-407.0
PYCRL	-3263.0	-3966.0
PYGB	-4498.0	2607.0
PYGL	-3546.0	2519.0
PYGM	-5462.0	-4695.0
QDPR	-1426.0	-4390.0
RAB14	2341.0	-431.0
RAB4A	1790.0	-3415.0
RAB5A	2109.0	4613.0
RAE1	4471.0	3078.0
RAN	2329.0	575.0
RANBP2	4470.0	-562.0
RAP1A	-689.0	3944.0
RAPGEF3	108.0	-2916.0
RAPGEF4	4622.0	4334.0
RBKS	-299.0	-73.0
RBP1	2113.0	2547.0
RDH11	2085.0	5274.0
RETSAT	2667.0	-4958.0
RFK	4952.0	-2511.0
RGL1	-161.0	-624.0
RNLS	1068.0	-337.0
RORA	-5056.0	2669.0
RPE	3419.0	-1547.0
RPIA	1665.0	-3077.0
RPL10	-3902.0	3923.0
RPL11	-2249.0	-1971.0
RPL14	433.0	-875.0
RPL18	-1782.0	448.0
RPL18A	-2969.0	-320.0
RPL19	-502.0	-1379.0
RPL22	1231.0	-3446.0
RPL22L1	3380.0	2374.0
RPL23	-115.0	-2882.0
RPL26	1047.0	696.0
RPL28	-391.0	-1891.0
RPL3	-786.0	5412.0
RPL30	286.0	-3056.0
RPL31	-595.0	2894.0
RPL32	-367.0	-950.0
RPL34	1447.0	-1314.0
RPL35A	812.0	-1471.0
RPL36A	1261.0	-1408.0
RPL37	-715.0	-1311.0
RPL37A	-1043.0	554.0
RPL38	231.0	-953.0
RPL3L	-5212.0	-4614.0
RPL4	-522.0	-571.0
RPL5	1206.0	3360.0
RPL7	1440.0	-1894.0
RPL8	-2775.0	-928.0
RPLP2	-2469.0	-3389.0
RPS11	-1582.0	-458.0
RPS12	-318.0	1501.0
RPS13	1131.0	-1994.0
RPS14	-1412.0	122.0
RPS15	-1799.0	-1082.0
RPS15A	-704.0	-237.0
RPS16	-1828.0	2010.0
RPS18	-974.0	-1404.0
RPS19	-2045.0	-882.0
RPS20	-1844.0	1712.0
RPS21	-1536.0	-2810.0
RPS23	-68.0	-749.0
RPS24	256.0	-1505.0
RPS26	-282.0	-1421.0
RPS27A	783.0	-2165.0
RPS27L	-616.0	-69.0
RPS29	-1140.0	-1275.0
RPS3	-544.0	116.0
RPS4X	83.0	97.0
RPS5	-1577.0	935.0
RPS6	-245.0	1237.0
RPS8	-1593.0	-1231.0
RPS9	-1107.0	-2477.0
RRM1	1649.0	-4051.0
RRM2B	-887.0	-4516.0
RUFY1	-2429.0	-2461.0
RXRA	-5519.0	1619.0
RXRB	-1250.0	-4283.0
SACM1L	4950.0	-3084.0
SAMD8	4892.0	3645.0
SAMHD1	48.0	-2043.0
SAR1B	2914.0	-3753.0
SARDH	-5204.0	1792.0
SAT1	4359.0	4723.0
SBF1	-3064.0	3930.0
SBF2	-32.0	-505.0
SC5D	440.0	-449.0
SCAP	-3464.0	-2817.0
SCD	-5600.0	4486.0
SCLY	2743.0	1227.0
SCO1	3577.0	-27.0
SCO2	-1941.0	-3526.0
SCP2	-862.0	-4948.0
SDC1	-2046.0	1023.0
SDC2	1756.0	4994.0
SDC3	-4619.0	2991.0
SDC4	-2393.0	5425.0
SDHA	-4773.0	-4748.0
SDHB	431.0	-4408.0
SDHC	-3712.0	-4323.0
SEC13	730.0	938.0
SEC23A	3177.0	-2521.0
SEC24A	4282.0	-949.0
SEC24B	3112.0	4347.0
SEC24C	2739.0	1142.0
SEC24D	265.0	4769.0
SECISBP2	1385.0	1739.0
SEH1L	1085.0	4110.0
SEPHS2	4570.0	5413.0
SEPSECS	733.0	3374.0
SERINC1	2847.0	-2384.0
SERINC2	-5279.0	295.0
SERINC3	1718.0	113.0
SERINC5	4920.0	609.0
SGMS1	3348.0	3879.0
SGMS2	-580.0	4263.0
SGPL1	836.0	4192.0
SGPP1	2488.0	3853.0
SGSH	710.0	206.0
SHMT1	-4478.0	-4921.0
SHMT2	-3440.0	347.0
SIN3A	3397.0	2893.0
SIN3B	1030.0	316.0
SLC16A1	-987.0	2280.0
SLC16A3	-4751.0	-4193.0
SLC19A1	-3727.0	-187.0
SLC19A2	2276.0	-1704.0
SLC22A5	-4653.0	-2437.0
SLC23A2	1949.0	2581.0
SLC25A1	-2688.0	4605.0
SLC25A11	-4108.0	-4483.0
SLC25A12	-5347.0	-4761.0
SLC25A13	4283.0	2507.0
SLC25A14	3834.0	1677.0
SLC25A16	1926.0	-4610.0
SLC25A17	4134.0	3081.0
SLC25A19	-626.0	-4877.0
SLC25A20	-3511.0	-3661.0
SLC25A27	-2478.0	-5079.0
SLC25A28	1627.0	825.0
SLC25A32	4603.0	-1848.0
SLC25A37	-4181.0	-3348.0
SLC25A44	4847.0	3872.0
SLC26A2	1389.0	4395.0
SLC27A1	-5082.0	-4976.0
SLC27A3	-132.0	589.0
SLC2A1	-2288.0	4700.0
SLC2A3	5004.0	2223.5
SLC35B2	-4343.0	94.0
SLC35B3	1732.0	3583.0
SLC35D1	1549.0	-539.0
SLC35D2	-2864.0	3053.0
SLC36A4	3115.0	4117.0
SLC37A1	-2590.0	-1968.0
SLC37A4	-4766.0	-4864.0
SLC3A2	-656.0	2824.0
SLC44A1	-686.0	1768.0
SLC44A2	-5438.0	-4047.0
SLC46A1	-3599.0	136.0
SLC52A2	1190.0	4215.0
SLC5A6	-433.0	2281.0
SLC6A8	-5538.0	5009.0
SLC7A5	-2463.0	5030.0
SLC9A1	-1056.0	1158.0
SMARCD3	-5399.0	-3136.0
SMOX	-1111.0	-2753.0
SMPD1	56.0	-2971.0
SMPD2	-1826.0	-2041.0
SMPD4	4257.0	675.0
SMS	-3038.0	1329.0
SORD	-2721.0	3684.0
SP1	1787.0	967.0
SPHK1	443.0	3667.0
SPHK2	-3750.0	3328.0
SPNS2	117.0	-820.0
SPR	-5076.0	-1210.0
SPTLC1	4025.0	577.0
SPTLC2	-355.0	3768.0
SPTSSA	61.0	-922.0
SQLE	-4496.0	4457.0
SQRDL	-4048.0	-3993.0
SRD5A3	3461.0	3052.0
SREBF1	-5230.0	273.0
SREBF2	-4703.0	4606.0
SRM	878.0	5017.0
SRR	-3331.0	223.0
ST3GAL1	-4505.0	4494.0
ST3GAL2	-2316.0	-1550.0
ST3GAL3	-4844.0	-3253.0
ST3GAL4	-2946.0	4173.0
ST3GAL6	-2222.0	-2871.0
ST6GALNAC6	-5270.0	-1855.0
STAB2	-3254.0	-3193.0
STARD10	-1854.0	-1182.0
STARD3	-137.0	-3408.0
STARD3NL	-868.0	4659.0
STARD4	-288.0	4385.0
STARD5	-3200.0	1094.0
STARD7	-4664.0	-4853.0
STK11	-4884.0	-3985.0
STX1A	-411.0	1598.0
STXBP1	-2263.0	3719.0
SUCLA2	1517.0	-4804.0
SUCLG1	-31.0	-4434.0
SUCLG2	-1167.0	-4765.0
SULT1A1	-2443.0	-4415.0
SUMF1	-289.0	-3291.0
SUMF2	-1393.0	1021.0
SUOX	-2894.0	-1655.0
SURF1	-1748.0	-3290.0
SYNJ1	4959.0	4035.0
SYNJ2	-3941.0	-5000.0
TACO1	651.0	-4903.0
TALDO1	-2080.0	-2543.0
TAZ	-3604.0	-4956.0
TBL1XR1	1876.0	528.0
TCN2	-1729.0	-1442.0
TECR	-4006.0	-2570.0
TGS1	4576.0	2855.0
THEM4	-3616.0	-2987.0
THRAP3	2457.0	1590.0
THRSP	-4308.0	441.0
THTPA	-2779.0	-4651.0
TIAM2	-3379.0	5429.0
TIMMDC1	213.0	-2918.0
TK1	-3225.0	-65.0
TK2	-3502.0	3950.0
TKT	-3051.0	3482.0
TM7SF2	-3964.0	-2222.0
TMEM126B	1024.0	1865.0
TMEM55B	3859.0	1390.0
TMEM86B	2486.0	585.0
TMLHE	-1794.0	-1601.0
TNFAIP8	-3086.0	2819.0
TNFAIP8L1	-3667.0	-2600.0
TNFRSF21	-2507.0	-3130.0
TPH1	-823.0	-1096.0
TPI1	-3377.0	-4322.0
TPK1	3959.0	-524.0
TPMT	2687.0	-2866.0
TPR	2984.0	275.0
TPST1	2003.0	-5.0
TPST2	-2855.0	-3991.0
TRAP1	-5265.0	-2862.0
TRIB3	-1004.0	2359.0
TSPO	-5144.0	3918.0
TST	-4513.0	-4118.0
TXN	1855.0	4827.0
TXN2	-2838.0	-2391.0
TXNRD1	-2444.0	4222.0
TYMS	-2042.0	3786.0
UBC	2672.0	3877.0
UBE2I	1246.0	733.0
UBIAD1	923.0	-2685.0
UCK1	-2612.0	-1232.0
UCK2	-3433.0	5509.0
UCKL1	-3830.0	-4159.0
UCP2	-4949.0	4253.0
UCP3	-684.0	-4891.0
UGCG	2596.0	1828.0
UGDH	2788.0	4858.0
UGP2	1387.0	-900.0
UMPS	1369.0	1409.0
UQCR10	-3139.0	-3068.0
UQCRB	403.0	-4257.0
UQCRC1	-3333.0	-4403.0
UQCRC2	551.0	-4650.0
UQCRFS1	-151.0	-4321.0
UQCRH	-1532.0	-4546.0
UQCRQ	-1767.0	-3443.0
UROD	795.0	-3628.0
UROS	-1848.0	-3787.0
UST	999.0	402.0
VAC14	-3820.0	2627.0
VAMP2	-3293.0	-1899.0
VAPA	2838.0	2825.0
VAPB	-1377.0	-3630.0
VCAN	1679.0	5186.0
VDAC1	-2909.0	-4782.0
VKORC1	-1589.0	579.0
VKORC1L1	-1211.0	452.0
WASL	2683.0	4511.0
XYLT1	2612.0	5340.0
XYLT2	-1138.0	-474.0
ZDHHC21	331.0	4563.0

---

---

Mitochondrial translation elongation

Mitochondrial translation elongation

metric	value
setSize	81
pMANOVA	4.11e-28
p.adjustMANOVA	6.33e-26
s.dist	0.683
s.human	0.158
s.mouse	-0.664
p.human	0.0139
p.mouse	4.54e-25

Top 20 genes

Gene	human	mouse
MRPL49	4766	-4287.0
GFM1	4202	-4858.0
MRPL44	4401	-4096.0
PTCD3	3483	-5093.0
MRPS22	4380	-3998.0
MRPL9	3433	-4876.0
MRPL16	3084	-4785.0
MRPL18	2996	-4773.0
MRPS35	3107	-4493.0
MRPL3	2973	-4380.0
MRPS31	3506	-3633.0
MRPL19	4079	-3047.0
MRPL15	2470	-4290.0
MRPL22	3353	-2865.0
MRPL30	3497	-2718.5
ERAL1	2608	-3520.0
MRPL11	2096	-4254.0
MRPL42	2106	-4149.0
TSFM	1964	-4406.0
MRPS14	1795	-4725.0

Click HERE to show all gene set members

All member genes

	human	mouse
AURKAIP1	-2308	-3467.0
CHCHD1	-543	-4442.0
DAP3	-463	354.0
ERAL1	2608	-3520.0
GADD45GIP1	-2418	-4820.0
GFM1	4202	-4858.0
MRPL1	-1296	-3497.0
MRPL10	-2406	-4655.0
MRPL11	2096	-4254.0
MRPL12	-2657	-3987.0
MRPL13	346	-1087.0
MRPL14	-1702	-2175.0
MRPL15	2470	-4290.0
MRPL16	3084	-4785.0
MRPL17	1930	1614.0
MRPL18	2996	-4773.0
MRPL19	4079	-3047.0
MRPL2	-437	-3027.0
MRPL20	538	-2975.0
MRPL21	1691	-1652.0
MRPL22	3353	-2865.0
MRPL23	-3221	-3820.0
MRPL24	-1884	-4451.0
MRPL27	-1616	-4786.0
MRPL28	-272	-3004.0
MRPL3	2973	-4380.0
MRPL30	3497	-2718.5
MRPL32	3068	3537.0
MRPL34	-2189	-4967.0
MRPL35	810	-3808.0
MRPL36	-560	-3281.0
MRPL37	1607	-4204.0
MRPL38	371	-3781.0
MRPL39	2592	-2566.0
MRPL4	2953	-2793.0
MRPL40	-250	-1725.0
MRPL41	-4898	-4188.0
MRPL42	2106	-4149.0
MRPL43	-1445	-3568.0
MRPL44	4401	-4096.0
MRPL46	1007	-2535.0
MRPL47	3173	-2238.0
MRPL48	-80	-1016.0
MRPL49	4766	-4287.0
MRPL50	3101	-1953.0
MRPL51	-389	-3858.0
MRPL52	-2314	-3091.0
MRPL54	-1999	-2160.0
MRPL55	1089	-4347.0
MRPL9	3433	-4876.0
MRPS10	-3085	-1917.0
MRPS11	283	-4954.0
MRPS12	-146	-4182.0
MRPS14	1795	-4725.0
MRPS15	1875	-4474.0
MRPS16	1205	-3440.0
MRPS17	-131	-2695.0
MRPS18A	469	-4626.0
MRPS18B	-1874	1045.0
MRPS18C	4378	-565.0
MRPS2	1441	-2634.0
MRPS22	4380	-3998.0
MRPS23	1674	-4542.0
MRPS25	-3561	-4702.0
MRPS26	-613	-4421.0
MRPS27	563	-4117.0
MRPS28	1356	-3864.0
MRPS30	3469	-2182.0
MRPS31	3506	-3633.0
MRPS33	152	-2442.0
MRPS34	-3846	-4787.0
MRPS35	3107	-4493.0
MRPS36	-2713	-3917.0
MRPS5	-1175	-4430.0
MRPS6	-4466	1321.0
MRPS7	-1337	-1519.0
MRPS9	1405	-4915.0
OXA1L	-2621	-3854.0
PTCD3	3483	-5093.0
TSFM	1964	-4406.0
TUFM	-2588	-4806.0

---

---

mRNA Splicing

mRNA Splicing

metric	value
setSize	169
pMANOVA	4.96e-28
p.adjustMANOVA	6.79e-26
s.dist	0.509
s.human	0.501
s.mouse	0.0926
p.human	3.5e-29
p.mouse	0.0386

Top 20 genes

Gene	human	mouse
CLP1	4787	5453
PDCD7	4447	5401
CDC40	4670	4950
PRPF40A	4797	4800
GTF2F1	4999	4439
ALYREF	5008	4414
POLR2A	3861	5366
WBP11	4711	4365
GTF2F2	4067	5047
BUD31	4578	4482
HNRNPU	4229	4805
HSPA8	3674	5419
AQR	3952	4831
CRNKL1	4682	3910
SNW1	3618	4892
HNRNPH1	3339	5250
SF3B4	4792	3548
HNRNPF	4978	3406
SF3B3	3615	4672
HNRNPA1	3878	4262

Click HERE to show all gene set members

All member genes

	human	mouse
ALYREF	5008	4414
AQR	3952	4831
BCAS2	4926	-4687
BUD31	4578	4482
CASC3	9	2673
CCAR1	3856	1341
CD2BP2	2749	-2336
CDC40	4670	4950
CDC5L	2693	369
CHERP	4498	2639
CLP1	4787	5453
CPSF1	-3670	977
CPSF2	-922	-1111
CPSF3	1953	2237
CPSF4	862	4202
CPSF7	407	-1612
CRNKL1	4682	3910
CSTF1	2216	1705
CSTF2	1437	-1058
CSTF2T	2703	4379
CSTF3	-2793	4119
CTNNBL1	-145	476
CWC15	4989	-1054
CWC22	4974	3088
CWC27	1809	-408
DDX23	-645	-2684
DDX42	2929	4353
DDX46	2094	-964
DDX5	4191	-363
DHX15	2483	4871
DHX16	3981	2235
DHX38	2857	440
DHX9	4151	2848
DNAJC8	4247	-942
EFTUD2	1157	3779
EIF4A3	4491	2615
ELAVL1	2256	1752
FIP1L1	3587	3058
FUS	867	4530
GCFC2	4300	2962
GPKOW	590	4338
GTF2F1	4999	4439
GTF2F2	4067	5047
HNRNPA0	2412	2009
HNRNPA1	3878	4262
HNRNPA2B1	3693	-4286
HNRNPA3	2505	2004
HNRNPC	3406	-403
HNRNPD	4343	3267
HNRNPF	4978	3406
HNRNPH1	3339	5250
HNRNPH2	2261	-2683
HNRNPK	3054	2807
HNRNPL	1064	-948
HNRNPM	4022	-4783
HNRNPR	4406	3418
HNRNPU	4229	4805
HNRNPUL1	2433	-725
HSPA8	3674	5419
ISY1	2662	-330
LSM2	-1347	-1539
LSM3	2210	-2101
LSM4	-2884	-2935
LSM5	2324	-1400
LSM6	-1177	-3681
LSM7	-3487	279
MAGOH	4561	555
MAGOHB	2239	-1880
NCBP1	-1736	4720
NCBP2	4188	-2519
NUDT21	3626	432
PCBP1	-3158	-362
PCF11	-1597	-2273
PDCD7	4447	5401
PHF5A	3478	-940
PLRG1	4237	-1621
POLR2A	3861	5366
POLR2B	4509	-3401
POLR2C	4529	-4002
POLR2D	1669	3230
POLR2E	-667	148
POLR2G	89	4349
POLR2H	-3927	2213
POLR2I	-154	-2504
POLR2K	2480	-3599
POLR2L	-4314	-1126
PPIE	2144	-1849
PPIH	594	-591
PPIL1	863	2264
PPIL3	4044	-732
PPIL4	3657	-3268
PPWD1	2992	-3786
PQBP1	-379	-3113
PRCC	2656	-830
PRPF19	2441	-4795
PRPF3	4719	3434
PRPF31	1339	3842
PRPF38A	4433	-314
PRPF4	3652	-1807
PRPF40A	4797	4800
PRPF6	684	3858
PRPF8	2926	-1861
PTBP1	3063	4580
PUF60	-2093	174
RBM17	2520	872
RBM22	709	1413
RBM5	3930	2323
RNPC3	-3052	2613
RNPS1	681	-2204
SART1	759	4758
SF1	4412	2651
SF3A1	3470	3133
SF3A2	2302	714
SF3A3	2871	2458
SF3B1	1067	5041
SF3B2	2676	-3889
SF3B3	3615	4672
SF3B4	4792	3548
SF3B5	1969	817
SLU7	4893	2372
SMNDC1	4537	2663
SNRNP200	2626	-3296
SNRNP25	2402	-2311
SNRNP27	2641	-3959
SNRNP35	-2744	-4385
SNRNP40	2967	2772
SNRNP48	4305	-1488
SNRNP70	-267	-2283
SNRPA1	4117	3762
SNRPB	3761	-2577
SNRPB2	4617	677
SNRPC	3677	-3134
SNRPD1	3996	1707
SNRPD2	2043	-2933
SNRPD3	2384	-3590
SNRPE	3421	-1387
SNRPF	3777	-2345
SNRPG	3179	3068
SNRPN	-2163	-1518
SNW1	3618	4892
SRRM1	2285	-2017
SRRM2	-1731	-1080
SRRT	4962	350
SRSF1	1871	-1493
SRSF11	3911	-1990
SRSF3	2586	1697
SRSF4	1929	3741
SRSF5	1997	-3060
SRSF6	1798	2387
SRSF7	3545	2132
SRSF9	3543	2675
SUGP1	-1552	-1352
SYF2	4472	-819
SYMPK	-3207	-1626
TFIP11	5002	2826
TRA2B	4288	3562
TXNL4A	-698	625
U2AF2	4337	2964
U2SURP	4199	-1543
UPF3B	1586	-4490
USP39	1526	1950
WBP11	4711	4365
WBP4	3659	671
WDR33	3143	-994
XAB2	2348	-818
YBX1	-681	-2174
ZCRB1	833	-4058
ZMAT5	1059	-2240
ZRSR2	4437	2554

---

---

Signal Transduction

Signal Transduction

metric	value
setSize	1401
pMANOVA	1.02e-27
p.adjustMANOVA	1.25e-25
s.dist	0.171
s.human	-0.0642
s.mouse	0.158
p.human	0.000103
p.mouse	9.04e-22

Top 20 genes

Gene	human	mouse
TNS3	-5416	5176
HSPB1	-4869	5539
BCAR1	-4922	5371
ARHGAP35	-4960	5279
SCD	-5600	4486
VCL	-4538	5383
FGF7	-5445	4475
RHOC	-4944	4844
P2RY6	-4646	5147
XK	-5173	4570
FOSL1	-4491	5244
CTTN	-4605	5097
NAB2	-5323	4380
WLS	-4973	4442
RANBP10	-4779	4540
PMEPA1	-4540	4777
GDNF	-4043	5263
FASN	-4976	4216
ARHGEF2	-4945	4225
LDLR	-3949	5260

Click HERE to show all gene set members

All member genes

	human	mouse
AAMP	2657	2106.0
ABCA1	1045	-2959.0
ABHD12	-778	-482.0
ABHD17A	-1525	-2873.0
ABHD17B	1639	3541.0
ABHD17C	-2092	-100.0
ABHD6	-2808	-530.0
ABI1	3792	3443.0
ABI2	-308	5438.0
ABL1	-4533	1377.0
ABR	-5353	3387.0
ACTA2	-3819	4068.0
ACTB	940	5427.0
ACTG1	-3075	5370.0
ACTN2	-3104	-1086.0
ACTR2	3547	5008.0
ACTR3	1376	5496.0
ACVR1B	-1186	-182.0
ACVR2A	3368	2290.0
ACVR2B	-3415	-963.0
ACVRL1	-2348	4734.0
ADAM10	-1509	1096.0
ADAM12	652	5402.0
ADAM17	2407	736.0
ADCY1	-3780	-756.0
ADCY2	-4820	-4790.0
ADCY3	338	612.0
ADCY5	1967	3217.0
ADCY6	-4515	-3045.0
ADCY7	-2820	3300.0
ADCY9	-4889	-2586.0
ADM	-1822	-3530.0
ADRA2A	-4661	-686.0
ADRB2	-1092	-929.0
AGO1	2453	283.0
AGO2	-4001	3296.0
AGO3	2529	188.0
AGO4	-3006	-1611.0
AGRN	-4903	783.0
AGT	-4723	-2282.0
AGTR1	1167	-2662.0
AHCTF1	4662	2760.0
AHCYL1	-3386	2570.0
AKAP13	1322	667.0
AKR1B10	2786	-1511.5
AKT1	-4954	1242.0
AKT1S1	271	-2763.0
AKT2	-4057	-3488.0
AKT3	1343	2419.0
ALDH1A1	-3063	-3653.0
ALDH1A2	-1560	5220.0
ALDH1A3	-260	3485.0
AMER1	-2488	1038.0
AMHR2	-2583	-2340.0
AMOT	-822	3288.0
AMOTL1	-3676	2159.0
AMOTL2	-4347	626.0
ANGPT1	-853	-3559.0
ANXA1	537	4783.0
AP2A1	-3632	-3002.0
AP2A2	-1058	5459.0
AP2B1	-1157	4733.0
AP2M1	-2746	1678.0
AP2S1	1777	-582.0
APC	3772	3182.0
APH1A	204	-3096.0
APH1B	3428	1940.0
APOD	-340	-633.0
APOE	-1428	-1396.0
APP	-2792	154.0
AR	-4468	-4062.0
ARAF	-3318	-4240.0
ARAP1	-4961	876.0
ARAP3	-1492	-3743.0
ARC	4190	3458.0
ARF6	3503	4901.0
ARHGAP1	-972	4196.0
ARHGAP10	-3294	-1719.0
ARHGAP11B	-4580	3163.0
ARHGAP12	-3916	-250.0
ARHGAP17	1457	2720.0
ARHGAP18	4554	-3352.0
ARHGAP19	4720	1553.0
ARHGAP20	4540	4124.0
ARHGAP21	2554	2948.0
ARHGAP22	-4747	2007.0
ARHGAP24	-3475	-798.0
ARHGAP26	-14	691.0
ARHGAP27	2783	-910.0
ARHGAP28	-5091	805.0
ARHGAP29	4465	-2049.0
ARHGAP31	-1030	-762.0
ARHGAP32	-1319	4859.0
ARHGAP33	-487	1323.0
ARHGAP35	-4960	5279.0
ARHGAP39	-3062	2351.0
ARHGAP4	-3966	4489.0
ARHGAP42	2893	964.0
ARHGAP44	686	5224.0
ARHGAP5	3942	-2428.0
ARHGAP6	4157	1982.0
ARHGAP9	-2941	-1677.0
ARHGDIA	-1439	4781.0
ARHGEF1	1054	-217.0
ARHGEF10L	-5596	682.0
ARHGEF11	-1199	2030.0
ARHGEF12	2630	5108.0
ARHGEF17	-5387	85.0
ARHGEF18	2304	-1935.0
ARHGEF2	-4945	4225.0
ARHGEF25	-2669	-1024.0
ARHGEF26	4815	3641.0
ARHGEF3	-4589	-823.0
ARHGEF37	-5129	127.0
ARHGEF4	-3700	211.0
ARHGEF40	-5458	2410.0
ARHGEF6	2856	4594.0
ARHGEF7	-3605	3212.0
ARHGEF9	-3989	-4009.0
ARL2	-4142	-2108.0
ARL4C	-1078	2148.0
ARPC1A	-120	2226.0
ARPC1B	669	4872.0
ARPC2	1357	2489.0
ARPC3	2873	1716.0
ARPC4	1698	-1177.0
ARPC5	2295	5164.0
ARRB1	-3133	2633.0
ARRB2	-1089	3740.0
ASH2L	-45	-4934.0
ATF1	3129	3005.0
ATF2	3130	2882.0
ATN1	-4709	3656.0
ATP1B4	-5072	3790.0
ATP2A1	-5479	-4435.0
ATP2A2	-2976	2104.0
ATP2A3	-4467	1381.0
ATP6AP1	-342	-3461.0
ATP6V0A1	-3809	3329.0
ATP6V0A2	186	-1285.0
ATP6V0B	-3461	-2887.0
ATP6V0D1	-2256	2038.0
ATP6V0E1	1861	1404.0
ATP6V0E2	-1727	-2450.0
ATP6V1A	1633	2509.0
ATP6V1B2	2299	4785.0
ATP6V1C1	3521	4933.0
ATP6V1D	3269	-4077.0
ATP6V1E1	3913	495.0
ATP6V1F	-3562	-1774.0
ATP6V1G2	1570	144.0
ATP6V1H	-57	1416.0
AXIN1	-730	3755.0
AXIN2	2452	1875.0
AXL	-4171	4393.0
B4GALT1	-1314	287.0
B9D2	1676	-3727.0
BAD	-1537	2913.0
BAG4	4135	3934.0
BAIAP2	-641	5424.0
BAMBI	1836	1766.0
BAX	-1846	4611.0
BCAR1	-4922	5371.0
BCL2	-4633	-3007.0
BCL2L1	-5181	430.0
BCL2L11	-4974	234.0
BCL9	-531	4556.0
BCL9L	-5611	2688.0
BCR	4627	2841.0
BDNF	1086	5317.0
BIRC2	3739	-1431.0
BIRC3	-4741	1787.0
BMI1	3349	3812.0
BMP2	-4256	1160.0
BMPR1A	2250	-522.0
BMPR1B	-2483	3041.0
BMPR2	-1969	145.0
BOC	-3568	346.0
BRAF	4103	3023.0
BRAP	4689	4314.0
BRK1	2026	-636.0
BTRC	-1187	-2761.0
BUB3	4201	-1316.0
C3	4311	-2705.0
CAB39	2485	4826.0
CAB39L	-2451	2119.0
CALCRL	2945	-2409.0
CALM1	-4464	1071.0
CAMK2A	-5527	-3819.0
CAMK2B	-5497	-2856.0
CAMK2D	-2223	5094.0
CAMK2G	-2097	-4184.0
CAMKK1	-3959	4041.0
CAMKK2	-4965	2096.0
CARM1	-4331	-1463.0
CASP2	2946	-2821.0
CASP3	423	5421.0
CASP8	-1646	3398.0
CASP9	-3269	-3219.0
CAV1	-646	-1312.0
CAV2	-403	-2015.0
CBFB	3786	-2549.0
CBL	1736	1563.0
CBX2	2360	-1727.0
CBX4	3208	4922.0
CBX6	-482	1921.0
CBX8	-917	-1786.0
CBY1	-2069	-5052.0
CCDC88C	-5319	-865.0
CCL2	2620	5213.0
CCNC	4650	3631.0
CCND1	757	1643.0
CCND3	786	1243.0
CCNE1	4388	4060.0
CCNK	3139	-346.0
CCNT1	4896	309.0
CCNT2	4381	-4634.0
CD28	-2910	-4611.0
CD55	220	-3197.0
CDC14A	957	-850.0
CDC14B	-1745	-3539.0
CDC37	-1724	-3392.0
CDC42	3308	965.0
CDC42EP2	-4230	-3919.0
CDC42EP3	-2886	-2995.0
CDC73	2659	3408.0
CDK1	1580	3204.0
CDK2	849	2902.0
CDK4	703	2603.0
CDK5	-1007	-2874.0
CDK8	623	-1266.0
CDK9	-1348	4755.0
CDKN1A	-4927	3046.0
CDKN1B	-3284	-2637.0
CDKN2B	-2827	-832.0
CDON	4423	1896.0
CENPC	3555	-133.0
CENPL	3768	3397.0
CENPO	1005	3332.0
CENPQ	1344	5114.0
CENPT	-2196	4477.0
CFL1	-909	5151.0
CFLAR	-5551	-3751.0
CHD1	4889	5266.0
CHD3	-3721	-2281.0
CHD4	-4283	1724.0
CHD8	4019	1245.0
CHN1	-5262	1681.0
CHN2	-4930	796.0
CHUK	216	3591.0
CILP	-417	4667.0
CIT	-2025	2541.0
CKAP5	-3973	78.0
CLASP1	-3713	3198.0
CLASP2	2507	2478.0
CLIP1	418	-371.0
CLIP3	-2233	2171.0
CLTA	1218	-119.0
CLTB	-4579	2521.0
CLTC	2268	2273.0
CMKLR1	193	3314.0
CNKSR1	-2870	3515.0
CNOT6L	-2201	3671.0
COL4A1	-4755	1270.0
COL4A2	-5035	827.0
COL4A3	-3831	-4180.0
COL4A4	-3022	-3438.0
COL4A5	-4320	-2713.0
COL6A1	-1945	2783.0
COL6A2	-1836	2972.0
COL6A3	-119	3607.0
COL6A6	-2138	-1882.0
CPT1A	-357	-839.0
CREB1	2179	-1920.0
CREBBP	1506	4134.0
CRK	2145	4206.0
CRKL	-91	5262.0
CSK	-3610	4728.0
CSNK1E	-5045	3424.0
CSNK1G2	-1933	-3089.0
CSNK2A1	1796	-2551.0
CSNK2A2	2123	2667.0
CSNK2B	1917	-1746.0
CTBP1	-3458	-2460.0
CTBP2	760	720.0
CTNNA1	-2198	2829.0
CTNNB1	1714	2956.0
CTNNBIP1	-4404	1193.0
CTNND1	949	4243.0
CTSD	-4817	-2585.0
CTTN	-4605	5097.0
CUL1	-3121	-833.0
CUL3	2833	3311.0
CUL5	2599	-2062.0
CX3CR1	307	4879.0
CXCL12	-4998	3271.0
CXCL16	-920	-543.0
CXXC5	-5255	-1175.0
CYBA	-633	2247.0
CYBB	-2550	3868.0
CYFIP2	-3775	-2981.0
CYLD	-1990	4116.0
CYP26B1	-756	811.0
CYP4V2	-2707	73.0
CYSLTR1	-4110	4012.0
DAAM1	3085	5018.0
DAB2IP	-5036	2828.0
DACT1	-2004	2444.0
DAGLA	-5158	-1202.0
DAGLB	3782	-3217.0
DDX5	4191	-363.0
DEPDC7	3273	2090.0
DERL2	2481	3942.0
DGKA	-2368	-2473.0
DGKB	-4489	-1599.0
DGKD	-5077	2121.0
DGKE	1911	-4489.0
DGKH	3337	3991.0
DGKQ	-2188	-3043.0
DGKZ	-5581	-3517.0
DHRS3	-611	377.0
DHRS4	-691	-4298.5
DIAPH1	3282	4405.0
DIAPH2	4914	5143.0
DKK2	-348	2271.0
DLAT	-1960	-4426.0
DLC1	4953	818.0
DLD	1187	-4834.0
DLG1	-52	2473.0
DLG3	-1567	-728.0
DLG4	-1594	1830.0
DLK1	-2814	-1918.0
DLL1	-3980	-2417.0
DNAJB1	4185	5356.0
DNAL4	-1632	-1736.0
DNM1	-747	1423.0
DNM2	-1149	218.0
DNM3	4865	1236.0
DOCK1	-226	2409.0
DOCK7	4461	2938.0
DOK1	-1380	-1735.0
DRAP1	-2364	-3203.0
DSN1	2075	-665.0
DTX2	1547	4166.0
DTX4	4372	-1688.0
DUSP1	-219	1965.0
DUSP10	-5329	1869.0
DUSP16	3082	3867.0
DUSP2	-4253	4725.0
DUSP3	-5149	-4856.0
DUSP4	-3613	786.0
DUSP5	4084	5436.0
DUSP6	-528	-3212.0
DUSP7	-3477	-3896.0
DUSP8	1715	4441.0
DVL1	-5428	-3679.0
DVL2	-2215	-3951.0
DVL3	-4897	2735.0
DYNC1H1	-1442	1264.0
DYNC1I2	2591	172.0
DYNC1LI1	2883	981.0
DYNC1LI2	1750	3473.0
DYNC2H1	4934	1458.0
DYNLL1	-1331	3935.0
DZIP1	-2494	644.0
E2F1	-529	4887.0
E2F3	-4683	2636.0
E2F4	-439	4952.0
E2F5	-249	1172.0
EBAG9	2473	-2474.0
ECE1	-1256	-853.0
ECE2	-294	1708.0
EDNRA	1038	2094.0
EDNRB	1473	-1220.0
EED	3304	3108.0
EEF2K	-5526	-4407.0
EEPD1	-3576	-2652.0
EGF	-4568	-4926.0
EGFR	424	2978.0
EGR1	4164	4986.0
EGR2	-3746	5163.0
EGR3	-3215	5298.0
EIF4B	993	-2864.0
EIF4E	2892	2481.0
EIF4EBP1	-1049	-251.0
EIF4G1	-2988	-962.0
ELK1	-3862	1269.0
ELMO1	-2166	2524.0
ELMO2	-354	1439.0
EP300	3403	2309.0
EPAS1	21	-4320.0
EPN1	-3102	-4701.0
EPS15	5	-415.0
EPS15L1	-444	-1146.0
ERBB2	-5511	494.0
ERBB3	-5290	-2307.0
ERLEC1	2742	-2895.0
ESR1	-1770	-2342.0
ETV4	-3510	2049.0
EVC	-2706	-4071.0
EVC2	1601	-1944.0
EVL	-3566	-1001.0
EZH2	4698	4282.0
F11R	-2302	-3195.0
F2R	1667	2871.0
F2RL1	3379	5479.0
F3	-1733	2873.0
FABP5	-338	587.0
FADD	-571	3829.0
FAM13A	4122	-561.0
FAM13B	3174	5059.0
FAS	-4771	2003.0
FASN	-4976	4216.0
FBXW7	-886	1644.0
FER	1666	4504.0
FES	559	2496.0
FGD1	-3972	3284.0
FGD3	-3665	3129.0
FGD4	-4717	-3651.0
FGF1	798	5410.0
FGF2	751	3502.0
FGF7	-5445	4475.0
FGF9	-5320	-1375.0
FGFBP3	3093	192.0
FGFR1	-1499	-1279.0
FGFR3	3759	4811.0
FGFR4	-5312	-991.0
FGFRL1	218	-514.0
FKBP4	1305	-2525.0
FKBP5	750	-1102.0
FLNA	-3248	4449.0
FLRT2	-4342	4178.0
FLRT3	4144	4853.0
FMNL1	-5159	-64.0
FMNL2	-650	4673.0
FMNL3	-1192	2401.0
FN1	35	4381.0
FNTA	1578	-3409.0
FNTB	-690	3507.0
FOS	1865	5350.0
FOSB	-4733	4375.0
FOSL1	-4491	5244.0
FOXO1	-432	3792.0
FOXO3	-42	2244.0
FOXO4	-3493	-3713.0
FOXO6	-4157	-792.0
FRAT2	4361	4437.0
FRK	194	2355.0
FRS2	4678	3571.0
FRS3	1398	1630.0
FST	-3089	2243.0
FSTL1	1459	4318.0
FSTL3	-3345	3946.0
FURIN	-4221	4897.0
FUZ	-3170	-4920.0
FYN	-2850	4537.0
FZD1	3076	4588.0
FZD10	-4859	-1478.0
FZD2	2092	2714.0
FZD4	-5151	-3086.0
FZD5	398	5121.0
FZD6	809	-1171.0
FZD7	1006	-1637.0
FZD8	-3582	-2814.0
FZD9	-5079	-4128.0
GAB1	-1853	-1642.0
GAB2	4053	2415.0
GABBR1	-2887	-778.0
GAS1	-4081	1491.0
GAS8	-3466	230.0
GATAD2A	-975	5411.0
GATAD2B	304	4882.0
GDI1	1662	1387.0
GDI2	865	4995.0
GDNF	-4043	5263.0
GFRA1	-4438	-426.0
GGA3	580	3687.0
GLI1	825	-1215.0
GLI2	-1180	3016.0
GLI3	3731	3520.0
GMIP	-2689	3331.0
GNA11	-1689	2150.0
GNA12	-3059	4306.0
GNA13	-209	5323.0
GNAI1	183	1373.0
GNAI2	800	2142.0
GNAI3	4221	4647.0
GNAL	-3374	3533.0
GNAQ	4906	4533.0
GNAS	-3163	-1742.0
GNB1	177	5374.0
GNB2	-3870	1232.0
GNB3	-3272	-676.0
GNB4	-3491	1634.0
GNB5	879	-2818.0
GNG11	4695	-4457.0
GNG12	612	604.0
GNG2	802	-2139.0
GNG5	415	-3220.0
GNG7	-2742	-4220.0
GOLGA7	1185	2154.0
GOPC	4735	-2584.0
GPAM	1132	-5046.0
GPC1	-5269	-1574.0
GPC4	-5170	-4334.0
GPC6	-2385	1959.0
GPNMB	-4186	-679.0
GPR161	3105	3425.0
GPR35	-3228	2443.0
GPS2	2002	-25.0
GPSM1	-3915	1306.0
GPSM2	-3093	3500.0
GRB10	-1615	3264.0
GRB2	-4050	3027.0
GREM2	-2122	-1653.0
GRK4	-1206	945.0
GRK5	-1067	-563.0
GRK6	-1110	2111.0
GSK3A	3319	-2089.0
GSK3B	897	4692.0
GTF2A1	4730	4204.0
GTF2A2	4648	-2956.0
GTF2F1	4999	4439.0
GTF2F2	4067	5047.0
H2AFX	2356	5181.0
HBEGF	3484	5518.0
HDAC10	-3116	762.0
HDAC11	-4482	3061.0
HDAC2	4386	-579.0
HDAC3	-178	-2363.0
HDAC4	-5061	-1561.0
HDAC5	-4921	3448.0
HDAC6	-4164	4690.0
HDAC7	-3827	-1671.0
HDAC8	209	-3383.0
HDAC9	-3759	4259.0
HEBP1	18	-537.0
HES1	1695	-3299.0
HEY1	4826	210.0
HEYL	-2812	-626.0
HGS	2410	5267.0
HHAT	2490	4059.0
HIF1A	-1016	5349.0
HNRNPA1	3878	4262.0
HNRNPF	4978	3406.0
HNRNPH1	3339	5250.0
HNRNPM	4022	-4783.0
HRAS	-4545	-4872.0
HSP90AA1	3656	5525.0
HSP90AB1	-639	5203.0
HSPB1	-4869	5539.0
HSPG2	-5351	1532.0
HTR7	2315	-3527.0
ICMT	-2315	2796.0
ID1	-1307	-719.0
ID2	3773	3303.0
ID3	-5372	624.0
ID4	4977	5182.0
IER3	1170	4376.0
IFT122	-4662	-2462.0
IFT140	-3441	1036.0
IFT172	-2711	-2812.0
IFT52	2101	-312.0
IFT57	2710	3679.0
IFT88	-1477	202.0
IGF1R	-144	1570.0
IGF2	-4754	2227.0
IKBKB	-4093	2980.0
IL17RD	-3179	1019.0
IL1RAP	627	4100.0
IL2RG	-1943	582.0
IL33	1864	3634.0
IL6R	-5515	2529.0
IL6ST	3055	1967.0
INCENP	3676	1455.0
INPP5B	2499	3885.0
INSR	-2945	-271.0
INTU	2230	2590.0
IQCE	-4375	1207.0
IQGAP1	-415	4295.0
IRAK1	-4351	-1420.0
IRAK4	-569	3445.0
IRS1	-5550	-3910.0
IRS2	3384	2249.0
ITCH	4319	2263.0
ITGA3	-5514	2747.0
ITGAV	-819	2947.0
ITGB1	956	5174.0
ITGB3	-488	5180.0
ITGB3BP	1048	-2794.0
ITPR1	4903	1106.0
ITPR2	1242	53.0
ITPR3	-3631	-2403.0
ITSN1	524	-2768.0
JAG1	3237	-943.0
JAG2	-5593	-1056.0
JAK1	-1869	4962.0
JAK2	-2569	-2171.0
JUN	2469	5472.0
JUNB	-2593	4931.0
JUND	1410	3318.0
JUP	1723	4991.0
KALRN	-5340	-990.0
KANK1	-2800	3356.0
KAT2A	-5053	-3388.0
KAT2B	-3340	-2881.0
KAT5	447	1402.0
KBTBD7	1566	3776.0
KCTD6	2748	2384.0
KDM1A	249	5433.0
KDM1B	-2581	4465.0
KDM3A	1176	2890.0
KDM4A	3714	51.0
KDM4B	-5221	2465.0
KDM4C	814	-807.0
KHDRBS1	3426	3543.0
KHDRBS3	964	-2323.0
KIDINS220	3922	-1933.0
KIF18A	3832	2448.0
KIF2A	-4390	4073.0
KIF3A	4718	3190.0
KIF5A	4430	584.0
KIF5B	838	4559.0
KIF7	-422	4356.0
KITLG	4898	-361.0
KLC1	-3922	2207.0
KLC2	-1732	-487.0
KLC4	-3559	-2759.0
KLHL12	-2571	-554.0
KMT2D	-1176	515.0
KPNA2	5007	4653.0
KRAS	3546	5146.0
KREMEN1	-5547	-699.0
KSR1	-5578	-1928.0
KTN1	1427	1915.0
LAMA2	-3799	1005.0
LAMA3	-1011	-1639.0
LAMA4	746	766.0
LAMA5	-5584	-201.0
LAMB1	-457	829.0
LAMB2	-4894	-176.0
LAMB3	-4991	-2671.0
LAMC1	-3224	3688.0
LAMC2	1351	5422.0
LAMC3	-1576	-3666.0
LAMTOR1	-800	-4509.0
LAMTOR2	-1715	-4532.0
LAMTOR3	3134	781.0
LAMTOR4	-2977	-641.0
LAMTOR5	636	-1109.0
LATS1	570	2682.0
LATS2	-438	-2055.0
LDLR	-3949	5260.0
LEO1	2784	-714.0
LEPR	3431	1776.0
LFNG	160	3838.0
LGR4	-2942	5320.0
LIMK1	-4857	3467.0
LIMK2	-5357	-3001.0
LPAR1	-2162	3140.0
LPAR4	-1042	-1474.0
LPAR6	2280	1088.0
LRIG1	-5443	437.0
LRP1	-3652	3049.0
LRP10	-3203	1445.0
LRP12	4543	5259.0
LRP5	-5463	-2155.5
LRP6	-277	3371.0
LRRK2	-2301	3142.0
LYN	785	2842.0
LYPLA1	1177	-3204.0
MAD1L1	-3382	1367.0
MAD2L1	1101	1981.0
MADD	-5238	-2940.0
MAF1	-1720	-2781.0
MAGED1	-3807	5158.0
MAML1	2770	4362.0
MAML2	2681	2618.0
MAML3	-2079	1098.0
MAMLD1	-1668	2661.0
MAP2K1	-506	-3734.0
MAP2K2	-3813	-2235.0
MAP2K5	-4711	-2589.0
MAP3K11	-3624	2252.0
MAP3K7	2142	1585.0
MAPK1	1988	-969.0
MAPK11	-3385	1370.0
MAPK12	-5264	99.0
MAPK14	-1562	-2824.0
MAPK3	-1024	4464.0
MAPK6	-2278	5077.0
MAPK7	-729	2102.0
MAPK8	457	1743.0
MAPKAP1	-405	1545.0
MAPKAPK2	-2489	-1825.0
MAPKAPK3	-4795	1592.0
MAPRE1	3454	5215.0
MARK3	3178	989.0
MBD3	-3419	804.0
MCF2L	-5254	1060.0
MDK	-2963	-2485.0
MDM2	3253	5156.0
MECOM	-3697	-380.0
MED1	4772	358.0
MEF2A	-5175	-1587.0
MEF2C	-4610	2307.0
MEF2D	-5348	-255.0
MEMO1	-1214	-328.0
MEN1	1348	426.0
MET	-3529	4440.0
METAP1	2806	-592.0
METAP2	0	1920.0
MGLL	-5374	-5059.0
MIB1	1332	3778.0
MIB2	-4266	194.0
MIS12	2400	5092.0
MKNK1	-2212	-3230.0
MKRN1	2493	-2142.0
MKS1	-1382	-869.0
MLST8	-3485	-1820.0
MMP2	-692	-606.0
MOB1A	1776	4867.0
MOB1B	-1284	-644.0
MOV10	-4127	-294.0
MRAS	-5239	525.0
MTA1	-4102	3149.0
MTA2	3682	-1298.0
MTA3	-2123	-1721.0
MTMR4	3209	4765.0
MTOR	-1191	583.0
MXD4	-1008	906.0
MYC	3994	185.0
MYD88	2726	2870.0
MYH10	50	5272.0
MYH14	-3853	-3524.0
MYH9	-1879	4997.0
MYL12B	1563	594.0
MYL6	-3628	1353.0
MYL9	-4777	-1049.0
MYLIP	-4026	-3523.0
MYLK	-3879	1507.0
MYO7A	-4056	2325.0
MYO9A	3168	3690.0
MYO9B	-1901	4621.0
NAB1	-3099	2676.0
NAB2	-5323	4380.0
NAPEPLD	-3083	3144.0
NBEA	-4442	-507.0
NCAM1	-3954	4316.0
NCBP1	-1736	4720.0
NCBP2	4188	-2519.0
NCK1	3718	2059.0
NCK2	-953	-4234.0
NCKAP1	3563	5090.0
NCKIPSD	-2821	3136.0
NCOA1	2628	708.0
NCOA2	146	558.0
NCOA3	4584	1433.0
NCOR1	2625	-1011.0
NCOR2	-5167	-143.0
NCSTN	-2504	-846.0
NDE1	4322	-1640.0
NDEL1	4631	3278.0
NEDD4	4583	-2859.0
NEDD4L	4279	95.0
NEDD8	-2678	-3615.0
NELFB	-1196	2017.0
NET1	-5146	2540.0
NEURL1B	-4776	-1991.0
NF1	3095	3040.0
NF2	-1449	-3031.0
NFATC1	-5337	-3274.0
NFKB1	-4233	2228.0
NFKBIA	-4263	1229.0
NGFR	1471	235.0
NLK	4629	2803.0
NLN	-3071	3578.0
NMB	-1654	-2613.0
NMT1	-1463	4510.0
NMT2	2059	4895.0
NOG	-4672	-2513.0
NOTCH1	-5460	-194.0
NOTCH3	-1225	2260.0
NR1H2	2288	2282.0
NR1H3	-3630	-3340.0
NR3C1	985	425.0
NR4A1	-5560	-1228.0
NRAS	4354	1003.0
NRIP1	-2652	4337.0
NRP1	-112	-3592.0
NRP2	2152	-1368.0
NSMAF	2025	-3471.0
NTF3	-2996	-2444.0
NTF4	-3432	-1335.0
NUDC	3212	-860.0
NUMB	2961	3921.0
NUP107	3232	3195.0
NUP133	889	-2580.0
NUP160	3998	2314.0
NUP37	-327	-873.0
NUP43	4562	193.0
NUP85	3181	227.0
NUP98	4235	5486.0
OBSCN	-5563	-275.0
OCRL	2293	3260.0
OFD1	811	-1859.0
OPHN1	616	-3566.0
OPN3	-2839	4784.0
OS9	-1493	-1811.0
OTUD3	3881	139.0
P2RY2	-5283	-3360.0
P2RY6	-4646	5147.0
P4HB	-2525	5054.0
PAFAH1B1	-2026	1737.0
PAG1	-2006	3400.0
PAK1	-5419	-4706.0
PAK2	1525	5331.0
PAQR3	396	3145.0
PARD3	367	-687.0
PARD6A	-1713	-3447.0
PARP1	-2423	278.0
PBX1	-4735	-1251.0
PCSK5	1905	3089.0
PCSK6	-3791	-944.0
PDE10A	2072	2109.0
PDE1A	2411	-405.0
PDE3A	315	468.0
PDE4A	-3306	-5113.0
PDE4B	3915	-2949.0
PDE4C	-2010	-3176.0
PDE4D	-1433	-3425.0
PDE6D	-2753	649.0
PDE7A	-2549	-3215.0
PDE7B	-2696	-5066.0
PDE8A	-324	3438.0
PDGFA	-4328	-2495.0
PDGFB	-606	1041.0
PDGFC	1650	3966.0
PDGFD	1552	-1845.0
PDGFRA	2727	1223.0
PDGFRB	-2260	2970.0
PDHA1	-2405	-4692.0
PDHB	-133	-4587.0
PDHX	-126	-4448.0
PDK1	4600	-3535.0
PDK2	-5450	-4464.0
PDK3	4747	5315.0
PDK4	-712	-4300.0
PDPK1	3443	3947.0
PEA15	-1982	1535.0
PEBP1	-3678	-3474.0
PELP1	2605	1451.0
PENK	634	-3005.0
PFN1	467	-2704.0
PFN2	-4209	-2786.0
PGF	-3714	661.0
PHB	-586	-3838.0
PHC1	456	3606.0
PHC2	-3719	5142.0
PHC3	3141	957.0
PHLPP1	4854	1554.0
PHLPP2	4694	2713.0
PIK3AP1	966	3017.0
PIK3C3	3439	-1596.0
PIK3CA	365	4218.0
PIK3CB	2760	5125.0
PIK3CD	-4322	-2306.0
PIK3R1	2896	-813.0
PIK3R3	3188	3545.0
PIK3R4	3839	-3124.0
PIN1	-3515	-3234.0
PIP4K2A	4108	4105.0
PIP4K2C	2827	4009.0
PIP5K1A	4918	3132.0
PIP5K1C	-1917	2945.0
PKN1	-4379	2357.0
PKN2	4933	5115.0
PKN3	-3848	310.0
PLA2G4A	603	4806.0
PLAT	1414	4193.0
PLB1	-3857	-1943.0
PLCB1	-1580	-2084.0
PLCB3	-3863	993.0
PLCB4	-4274	-2681.0
PLCG1	-3955	-1787.0
PLEKHG2	-708	4175.0
PLEKHG5	-4706	-2803.0
PLTP	-303	1497.0
PLXNB1	-5451	-185.0
PLXND1	-4476	-1332.0
PMEPA1	-4540	4777.0
PML	3338	3242.0
POFUT1	-2274	-1749.0
POGLUT1	-1951	-2001.0
POLR2A	3861	5366.0
POLR2B	4509	-3401.0
POLR2C	4529	-4002.0
POLR2D	1669	3230.0
POLR2E	-667	148.0
POLR2G	89	4349.0
POLR2H	-3927	2213.0
POLR2I	-154	-2504.0
POLR2K	2480	-3599.0
POLR2L	-4314	-1126.0
PORCN	647	-1815.0
POU2F1	3019	-1366.0
PPARD	-4213	2330.0
PPARG	-1621	-2602.0
PPID	642	-3382.0
PPM1A	3438	-2375.0
PPP1CA	-4408	-15.0
PPP1CB	-1374	-3335.0
PPP1CC	4081	-1627.0
PPP1R12A	4131	4053.0
PPP1R12B	-5005	2701.0
PPP1R15A	1886	5532.0
PPP2CA	4482	1672.0
PPP2CB	2458	2352.0
PPP2R1A	-4013	-681.0
PPP2R1B	3028	3194.0
PPP2R5A	4590	3889.0
PPP2R5B	-1524	-765.0
PPP2R5C	-2508	-293.0
PPP2R5D	-3449	-620.0
PPP2R5E	4644	2107.0
PPP3CA	109	-1172.0
PPP3CB	-3435	-1839.0
PPP3CC	-3311	-2196.0
PPP5C	-4582	-3591.0
PRC1	112	4093.0
PRDM4	2865	3922.0
PREX1	188	2037.0
PRICKLE1	827	-2038.0
PRKAA1	3389	2399.0
PRKAA2	-3219	-2647.0
PRKAB1	3436	2257.0
PRKAB2	-2332	-3109.0
PRKACA	-4691	-4303.0
PRKACB	-2659	-360.0
PRKAG1	2103	-3125.0
PRKAG2	-3237	502.0
PRKAG3	-5537	-2369.0
PRKAR1A	-3106	203.0
PRKAR1B	-2442	3659.0
PRKAR2A	-2664	1823.0
PRKAR2B	3460	1006.0
PRKCA	-2938	1125.0
PRKCD	-4276	1141.0
PRKCE	-4307	-348.0
PRKCI	416	2569.0
PRKCQ	-5095	-4724.0
PRKG1	1401	5353.0
PRKX	-1471	5241.0
PRR5	-837	161.0
PSAP	-2247	-4177.0
PSEN1	2070	3570.0
PSEN2	-5371	-3111.0
PSENEN	-2638	-2344.0
PSMA1	2820	4043.0
PSMA3	3434	-1035.0
PSMA4	769	-1962.0
PSMA6	2199	-1657.0
PSMA7	-2980	-1038.0
PSMB1	954	-1037.0
PSMB10	-1800	-831.0
PSMB2	618	-67.0
PSMB4	-235	-559.0
PSMB5	-4113	-2597.0
PSMB6	-793	-1795.0
PSMB7	-831	-2699.0
PSMB8	-675	-2510.0
PSMB9	-1611	-3558.0
PSMC1	449	1146.0
PSMC2	-1311	3386.0
PSMC3	-2439	-1846.0
PSMC4	2724	-205.0
PSMC5	1212	-1680.0
PSMC6	-2520	3114.0
PSMD1	2619	3210.0
PSMD10	-1227	361.0
PSMD11	995	5504.0
PSMD12	3831	-462.0
PSMD13	821	532.0
PSMD14	-635	3746.0
PSMD2	-713	741.0
PSMD3	-3343	-354.0
PSMD4	-214	968.0
PSMD5	1807	4479.0
PSMD6	3537	-3784.0
PSMD7	-2329	410.0
PSMD8	-3171	4292.0
PSMD9	4204	-3586.0
PSME1	-2771	-2861.0
PSME2	-4085	-41.0
PSME3	3333	491.0
PSME4	1960	2319.0
PSMF1	683	-1768.0
PTBP1	3063	4580.0
PTCH1	326	-672.0
PTCH2	-2962	1015.0
PTEN	2797	4830.0
PTGER4	4219	2196.0
PTGES3	1328	2246.0
PTGIR	-370	3747.0
PTH1R	-2770	-90.0
PTHLH	-3836	-66.0
PTK2	-2497	2145.0
PTK2B	-2461	2430.0
PTPN1	1531	4935.0
PTPN11	-1575	3105.0
PTPN12	4141	5222.0
PTPN18	-4024	2162.0
PTPN2	4314	5012.0
PTPN3	2224	-5017.0
PTPN6	-931	4180.0
PTPRA	-402	3484.0
PTPRJ	391	4189.0
PTPRK	211	1310.0
PTPRO	1419	2718.0
PTPRS	-4613	-4065.0
PXN	-4750	1059.0
PYGO1	-1566	-2789.0
PYGO2	-2448	5071.0
RAB4A	1790	-3415.0
RAC1	2525	-240.0
RAC2	41	4138.0
RACGAP1	4239	3807.0
RAD21	4417	4961.0
RAF1	1712	-1201.0
RALA	-1368	-1154.0
RALB	-2362	780.0
RALBP1	2524	2961.0
RALGDS	-5190	2802.0
RAMP1	-5448	-646.0
RANBP10	-4779	4540.0
RANBP2	4470	-562.0
RANBP9	4005	2691.0
RANGAP1	483	4468.0
RAP1A	-689	3944.0
RAP1B	4479	5079.0
RAPGEF1	-3992	4925.0
RAPGEF2	4504	-1660.0
RAPGEF3	108	-2916.0
RAPGEF4	4622	4334.0
RARA	-5250	1555.0
RARB	-2995	-231.0
RARG	-4431	-1193.0
RASA1	-612	2537.0
RASA2	3565	2417.0
RASA3	-4990	-58.0
RASAL2	3510	686.0
RASGRF2	4373	-3126.0
RASGRP2	-2556	-4004.0
RASGRP3	-4774	-4929.0
RBBP4	1072	728.0
RBBP5	4628	1244.0
RBBP7	-924	-1007.0
RBCK1	-4445	-2999.0
RBFOX2	-4887	-2254.0
RBL1	-1617	-993.0
RBP1	2113	2547.0
RBPJ	305	5264.0
RBX1	-733	-2400.0
RCC2	4178	3180.0
RCE1	2361	2291.0
RCOR1	4776	3876.0
RDH10	1095	4775.0
RDH11	2085	5274.0
RDH13	-3663	-1424.0
RDH14	4051	-4555.0
RDH5	-3933	1560.0
REEP1	-5059	-2153.0
REEP2	-2968	-463.0
REEP3	2053	4553.0
REEP4	1148	4143.0
REEP5	-3723	-3834.0
REEP6	-1143	-450.0
RELA	1783	4454.0
REST	1113	2845.0
RETSAT	2667	-4958.0
RFNG	-4947	1608.0
RGL1	-161	-624.0
RGL2	-4344	-4226.0
RGS10	-785	2024.0
RGS12	-4393	2043.0
RGS14	-5528	-1896.0
RGS16	-723	5075.0
RGS19	-2099	3025.0
RGS2	-581	4051.0
RGS3	-5494	3152.0
RGS4	1724	4741.0
RGS5	2155	-3665.0
RGS9BP	-2609	4386.0
RHEB	172	1360.0
RHOA	539	4106.0
RHOB	4609	4443.0
RHOBTB1	4915	-1398.0
RHOBTB2	-3428	-4485.0
RHOC	-4944	4844.0
RHOG	-1207	5167.0
RHOJ	164	1325.0
RHOQ	-1357	-1546.0
RHOT1	-3626	-2070.0
RHOT2	-5266	-4422.0
RHOU	-4229	-3685.0
RHPN2	3217	517.0
RICTOR	3562	1082.0
RING1	-1968	-3185.0
RIPK1	325	189.0
RIPK2	3609	4684.0
RIT1	4448	1706.0
RNF111	3964	5247.0
RNF146	-3773	2925.0
RNF2	3038	4841.0
RNF31	-839	-479.0
RNF41	1588	4825.0
ROCK1	4876	3865.0
ROCK2	2205	1929.0
ROR1	-187	-359.0
ROR2	428	3111.0
RPGRIP1L	1195	1885.0
RPS27A	783	-2165.0
RPS6	-245	1237.0
RPS6KA1	-1481	-1813.0
RPS6KA2	-4748	-4135.0
RPS6KA3	952	2296.0
RPS6KA5	51	-4805.0
RPS6KB1	2776	1292.0
RPS6KB2	-4132	1465.0
RPTOR	-4596	3929.0
RRAD	4389	4932.0
RRAGA	2383	4039.0
RRAGB	-366	123.0
RRAGC	2091	1975.0
RRAGD	-4673	-3366.0
RTKN	-5092	-1124.0
RTN4	-2844	-2986.0
RUNX1	-2434	5228.0
RUVBL1	-1240	-1693.0
RXRA	-5519	1619.0
RXRB	-1250	-4283.0
RXRG	-4055	-290.0
RYK	1626	-1060.0
S1PR1	2689	-1019.0
S1PR2	520	3630.0
S1PR3	2047	-31.0
SAV1	3362	-1495.0
SCAI	-726	-536.0
SCD	-5600	4486.0
SCMH1	-5007	-899.0
SCRIB	-5277	3547.0
SCUBE2	-3745	2375.0
SDC1	-2046	1023.0
SDC2	1756	4994.0
SDC3	-4619	2991.0
SDC4	-2393	5425.0
SEC13	730	938.0
SEH1L	1085	4110.0
SEL1L	3241	683.0
SERPINE1	-211	5469.0
SFPQ	4544	4884.0
SFRP1	2147	353.0
SFRP2	-1497	1575.0
SGK1	1084	-4376.0
SH2B1	-3841	1127.0
SH2B2	-4553	2511.0
SH2B3	-4833	4233.0
SH3GL1	-2937	2600.0
SH3KBP1	1014	-4274.0
SHARPIN	-3397	-4382.0
SHC1	3976	4815.0
SHC2	-3710	3451.0
SHOC2	4514	3567.0
SIRT6	1524	2954.0
SKA2	2399	946.0
SKI	-3187	2909.0
SKIL	1818	4329.0
SKP1	2028	-1286.0
SLC38A9	969	1822.0
SMAD1	-2920	5408.0
SMAD2	1125	5372.0
SMAD3	-3794	-3710.0
SMAD4	2354	2716.0
SMAD5	3745	4813.0
SMAD6	2009	-1203.0
SMAD7	-1051	3680.0
SMAD9	517	453.0
SMARCA4	-3874	863.0
SMC1A	3824	-118.0
SMC3	4878	2611.0
SMO	-4360	3150.0
SMPD2	-1826	-2041.0
SMURF1	4443	-1337.0
SMURF2	1070	5348.0
SNAI1	4055	3437.0
SNAI2	-1085	2033.0
SNW1	3618	4892.0
SNX3	289	3056.0
SOCS1	199	3983.0
SOCS3	-283	4943.0
SOCS6	-2366	3321.0
SOS1	-1962	2326.0
SOS2	-563	-2646.0
SOX13	-4049	-575.0
SOX4	-977	4631.0
SOX6	-1218	-804.0
SOX9	2175	5346.0
SP1	1787	967.0
SPARC	-2672	1436.0
SPHK1	443	3667.0
SPOP	-4970	-4969.0
SPOPL	913	-2494.0
SPP1	1162	2350.0
SPPL2A	1672	-4538.0
SPRED1	3312	4628.0
SPRED2	1200	-1956.0
SPRED3	-2447	-207.0
SPRY1	4004	-2764.0
SPRY2	-3817	2177.0
SPTAN1	-2425	412.0
SPTB	-5499	1118.0
SPTBN1	-2919	-1221.0
SQSTM1	-3803	4448.0
SRC	-3910	3763.0
SREBF1	-5230	273.0
SRF	-4281	3531.0
SRGAP1	938	2617.0
SRGAP3	-3043	3924.0
ST3GAL3	-4844	-3253.0
ST3GAL4	-2946	4173.0
ST3GAL6	-2222	-2871.0
STAG1	4246	505.0
STAG2	31	-897.0
STAM	3932	5249.0
STAM2	3489	4749.0
STAP2	-2832	-3748.0
STARD13	-4235	4774.0
STARD8	-2599	3031.0
STAT1	236	-3457.0
STAT3	-3885	5276.0
STAT5A	-4125	-4449.0
STAT5B	-5022	-3552.0
STAT6	-5317	-88.0
STK11	-4884	-3985.0
STK3	4986	2287.0
STK4	3116	2026.0
STMN1	-959	1185.0
STRADA	-1805	-131.0
STRADB	741	-3375.0
STRAP	3710	-974.0
STRN	-104	4484.0
STUB1	-2898	-3668.0
SUFU	-1035	3517.0
SUZ12	3871	4598.0
SYDE1	-968	1574.0
SYDE2	-263	-1014.0
SYNGAP1	-3658	2878.0
SYVN1	-192	4220.0
TAB1	-4874	-4377.0
TAB2	2791	3798.0
TAB3	2116	5258.0
TACC3	-1415	2558.0
TAOK1	1644	130.0
TAS1R1	-4010	-2497.0
TAX1BP1	3222	-87.0
TAX1BP3	-710	3864.0
TBL1XR1	1876	528.0
TBP	1137	3931.0
TCF12	1614	4852.0
TCF4	3907	-2353.0
TCF7	1204	-1623.0
TCF7L1	-3205	750.0
TCF7L2	-74	716.0
TCIRG1	-3600	4574.0
TEC	3728	3350.0
TEK	3580	-1484.0
TFDP1	-2245	-3110.0
TFDP2	4029	-4963.0
TGFB1	-3111	4516.0
TGFBR1	-2914	3771.0
TGFBR2	-927	2514.0
TGIF1	-2131	2058.0
THBS1	762	5034.0
THBS2	379	1016.0
THBS3	-4348	2778.0
THBS4	-280	3054.0
THEM4	-3616	-2987.0
TIA1	3336	-1995.0
TIAL1	1738	-1479.0
TIAM1	2024	-347.0
TIAM2	-3379	5429.0
TJP1	405	-780.0
TJP2	784	4364.0
TLE1	3589	-924.0
TLE2	-3403	793.0
TLE3	-5298	3523.0
TLE4	3498	4951.0
TLN1	-3918	3071.0
TMED2	2813	-1663.0
TMED5	4129	1889.0
TNFAIP3	-5203	3469.0
TNFRSF10A	-3936	485.5
TNFRSF10B	-1612	485.5
TNFRSF10D	-3227	485.5
TNFRSF1A	-4666	3341.0
TNKS	2621	4972.0
TNKS2	4726	-1242.0
TNRC6A	3585	2923.0
TNRC6B	3118	-2855.0
TNRC6C	-2020	1056.0
TNS3	-5416	5176.0
TP53	575	3128.0
TPH1	-823	-1096.0
TRADD	-706	-1945.0
TRAF1	-969	-1147.0
TRAF2	-1546	2643.0
TRAF6	3468	4662.0
TRIB1	-2384	5069.0
TRIB3	-1004	2359.0
TRIM27	4120	2963.0
TRIM33	2796	3628.0
TRIO	1163	-378.0
TRIP10	-4547	-4755.0
TRRAP	4073	1746.0
TSC1	2577	2054.0
TSC2	-4999	760.0
TTC21B	2366	-1026.0
TULP3	-2192	1344.0
TYK2	-3123	725.0
UBC	2672	3877.0
UBE2D1	-1588	-4657.0
UBE2D3	1424	5192.0
UBE2M	1247	-854.0
UCHL5	1313	-3924.0
UHMK1	4180	-814.0
ULK3	-5363	1379.0
USF1	3062	-451.0
USF2	-3406	-4636.0
USP13	-3948	340.0
USP15	4197	-4690.0
USP2	-5039	-3331.0
USP21	-1420	2353.0
USP34	3176	1375.0
USP4	276	1138.0
USP7	3857	2483.0
USP8	4301	-947.0
USP9X	1458	-295.0
UTS2R	-5043	1755.0
VANGL2	-5207	-1946.0
VAPA	2838	2825.0
VAV2	-4959	2847.0
VAV3	187	-276.0
VCL	-4538	5383.0
VEGFA	-4571	-5070.0
VEGFB	-4617	-3478.0
VEGFC	1169	2268.0
VPS26A	3259	3122.0
VPS29	-241	2861.0
VPS35	2429	-506.0
VRK3	464	3294.0
VWF	-779	1730.0
WASF2	-4656	3026.0
WASF3	-1015	1293.0
WASL	2683	4511.0
WDR19	1384	3724.0
WDR35	2475	-4633.0
WDR83	1010	-3938.0
WIPF1	-2552	2457.0
WIPF2	3299	-608.0
WIPF3	-5107	-4936.0
WLS	-4973	4442.0
WNT11	-5040	-3868.0
WNT4	-5296	-1155.0
WNT5A	1837	-1443.0
WNT5B	-2395	-2354.0
WNT9A	-4855	-1823.0
WWOX	1055	-3485.0
WWP1	-1200	-3658.0
WWP2	-1852	3455.0
WWTR1	-2503	3401.0
XK	-5173	4570.0
XPO1	990	2133.0
YAP1	-476	5038.0
YBX1	-681	-2174.0
YES1	-176	-836.0
YWHAB	3680	3468.0
YWHAE	1394	-2051.0
YWHAG	-2372	1012.0
YWHAH	-2777	3808.0
YWHAQ	963	3949.0
YWHAZ	2019	4919.0
ZDHHC21	331	4563.0
ZDHHC7	671	2765.0
ZDHHC9	-3396	2752.0
ZFYVE16	-2702	-1620.0
ZFYVE9	-3150	-2046.0
ZNF217	4998	4610.0
ZNRF3	-803	4587.0
ZRANB1	2309	1499.0
ZW10	1474	3364.0
ZWINT	2778	5457.0

---

---

mRNA Splicing - Major Pathway

mRNA Splicing - Major Pathway

metric	value
setSize	161
pMANOVA	1.37e-27
p.adjustMANOVA	1.54e-25
s.dist	0.519
s.human	0.508
s.mouse	0.104
p.human	1.02e-28
p.mouse	0.0236

Top 20 genes

Gene	human	mouse
CLP1	4787	5453
CDC40	4670	4950
PRPF40A	4797	4800
GTF2F1	4999	4439
ALYREF	5008	4414
POLR2A	3861	5366
WBP11	4711	4365
GTF2F2	4067	5047
BUD31	4578	4482
HNRNPU	4229	4805
HSPA8	3674	5419
AQR	3952	4831
CRNKL1	4682	3910
SNW1	3618	4892
HNRNPH1	3339	5250
SF3B4	4792	3548
HNRNPF	4978	3406
SF3B3	3615	4672
HNRNPA1	3878	4262
PRPF3	4719	3434

Click HERE to show all gene set members

All member genes

	human	mouse
ALYREF	5008	4414
AQR	3952	4831
BCAS2	4926	-4687
BUD31	4578	4482
CASC3	9	2673
CCAR1	3856	1341
CD2BP2	2749	-2336
CDC40	4670	4950
CDC5L	2693	369
CHERP	4498	2639
CLP1	4787	5453
CPSF1	-3670	977
CPSF2	-922	-1111
CPSF3	1953	2237
CPSF4	862	4202
CPSF7	407	-1612
CRNKL1	4682	3910
CSTF1	2216	1705
CSTF2	1437	-1058
CSTF2T	2703	4379
CSTF3	-2793	4119
CTNNBL1	-145	476
CWC15	4989	-1054
CWC22	4974	3088
CWC27	1809	-408
DDX23	-645	-2684
DDX42	2929	4353
DDX46	2094	-964
DDX5	4191	-363
DHX15	2483	4871
DHX16	3981	2235
DHX38	2857	440
DHX9	4151	2848
DNAJC8	4247	-942
EFTUD2	1157	3779
EIF4A3	4491	2615
ELAVL1	2256	1752
FIP1L1	3587	3058
FUS	867	4530
GCFC2	4300	2962
GPKOW	590	4338
GTF2F1	4999	4439
GTF2F2	4067	5047
HNRNPA0	2412	2009
HNRNPA1	3878	4262
HNRNPA2B1	3693	-4286
HNRNPA3	2505	2004
HNRNPC	3406	-403
HNRNPD	4343	3267
HNRNPF	4978	3406
HNRNPH1	3339	5250
HNRNPH2	2261	-2683
HNRNPK	3054	2807
HNRNPL	1064	-948
HNRNPM	4022	-4783
HNRNPR	4406	3418
HNRNPU	4229	4805
HNRNPUL1	2433	-725
HSPA8	3674	5419
ISY1	2662	-330
LSM2	-1347	-1539
LSM3	2210	-2101
LSM4	-2884	-2935
LSM5	2324	-1400
LSM6	-1177	-3681
LSM7	-3487	279
MAGOH	4561	555
MAGOHB	2239	-1880
NCBP1	-1736	4720
NCBP2	4188	-2519
NUDT21	3626	432
PCBP1	-3158	-362
PCF11	-1597	-2273
PHF5A	3478	-940
PLRG1	4237	-1621
POLR2A	3861	5366
POLR2B	4509	-3401
POLR2C	4529	-4002
POLR2D	1669	3230
POLR2E	-667	148
POLR2G	89	4349
POLR2H	-3927	2213
POLR2I	-154	-2504
POLR2K	2480	-3599
POLR2L	-4314	-1126
PPIE	2144	-1849
PPIH	594	-591
PPIL1	863	2264
PPIL3	4044	-732
PPIL4	3657	-3268
PPWD1	2992	-3786
PQBP1	-379	-3113
PRCC	2656	-830
PRPF19	2441	-4795
PRPF3	4719	3434
PRPF31	1339	3842
PRPF38A	4433	-314
PRPF4	3652	-1807
PRPF40A	4797	4800
PRPF6	684	3858
PRPF8	2926	-1861
PTBP1	3063	4580
PUF60	-2093	174
RBM17	2520	872
RBM22	709	1413
RBM5	3930	2323
RNPS1	681	-2204
SART1	759	4758
SF1	4412	2651
SF3A1	3470	3133
SF3A2	2302	714
SF3A3	2871	2458
SF3B1	1067	5041
SF3B2	2676	-3889
SF3B3	3615	4672
SF3B4	4792	3548
SF3B5	1969	817
SLU7	4893	2372
SMNDC1	4537	2663
SNRNP200	2626	-3296
SNRNP27	2641	-3959
SNRNP40	2967	2772
SNRNP70	-267	-2283
SNRPA1	4117	3762
SNRPB	3761	-2577
SNRPB2	4617	677
SNRPC	3677	-3134
SNRPD1	3996	1707
SNRPD2	2043	-2933
SNRPD3	2384	-3590
SNRPE	3421	-1387
SNRPF	3777	-2345
SNRPG	3179	3068
SNRPN	-2163	-1518
SNW1	3618	4892
SRRM1	2285	-2017
SRRM2	-1731	-1080
SRRT	4962	350
SRSF1	1871	-1493
SRSF11	3911	-1990
SRSF3	2586	1697
SRSF4	1929	3741
SRSF5	1997	-3060
SRSF6	1798	2387
SRSF7	3545	2132
SRSF9	3543	2675
SUGP1	-1552	-1352
SYF2	4472	-819
SYMPK	-3207	-1626
TFIP11	5002	2826
TRA2B	4288	3562
TXNL4A	-698	625
U2AF2	4337	2964
U2SURP	4199	-1543
UPF3B	1586	-4490
USP39	1526	1950
WBP11	4711	4365
WBP4	3659	671
WDR33	3143	-994
XAB2	2348	-818
YBX1	-681	-2174

---

---

Mitochondrial translation initiation

Mitochondrial translation initiation

metric	value
setSize	81
pMANOVA	1.72e-27
p.adjustMANOVA	1.77e-25
s.dist	0.676
s.human	0.152
s.mouse	-0.659
p.human	0.0186
p.mouse	1.12e-24

Top 20 genes

Gene	human	mouse
MRPL49	4766	-4287.0
MRPL44	4401	-4096.0
PTCD3	3483	-5093.0
MRPS22	4380	-3998.0
MRPL9	3433	-4876.0
MRPL16	3084	-4785.0
MRPL18	2996	-4773.0
MRPS35	3107	-4493.0
MRPL3	2973	-4380.0
MRPS31	3506	-3633.0
MRPL19	4079	-3047.0
MRPL15	2470	-4290.0
MRPL22	3353	-2865.0
MRPL30	3497	-2718.5
ERAL1	2608	-3520.0
MRPL11	2096	-4254.0
MRPL42	2106	-4149.0
MRPS14	1795	-4725.0
MRPS15	1875	-4474.0
MRPL4	2953	-2793.0

Click HERE to show all gene set members

All member genes

	human	mouse
AURKAIP1	-2308	-3467.0
CHCHD1	-543	-4442.0
DAP3	-463	354.0
ERAL1	2608	-3520.0
GADD45GIP1	-2418	-4820.0
MRPL1	-1296	-3497.0
MRPL10	-2406	-4655.0
MRPL11	2096	-4254.0
MRPL12	-2657	-3987.0
MRPL13	346	-1087.0
MRPL14	-1702	-2175.0
MRPL15	2470	-4290.0
MRPL16	3084	-4785.0
MRPL17	1930	1614.0
MRPL18	2996	-4773.0
MRPL19	4079	-3047.0
MRPL2	-437	-3027.0
MRPL20	538	-2975.0
MRPL21	1691	-1652.0
MRPL22	3353	-2865.0
MRPL23	-3221	-3820.0
MRPL24	-1884	-4451.0
MRPL27	-1616	-4786.0
MRPL28	-272	-3004.0
MRPL3	2973	-4380.0
MRPL30	3497	-2718.5
MRPL32	3068	3537.0
MRPL34	-2189	-4967.0
MRPL35	810	-3808.0
MRPL36	-560	-3281.0
MRPL37	1607	-4204.0
MRPL38	371	-3781.0
MRPL39	2592	-2566.0
MRPL4	2953	-2793.0
MRPL40	-250	-1725.0
MRPL41	-4898	-4188.0
MRPL42	2106	-4149.0
MRPL43	-1445	-3568.0
MRPL44	4401	-4096.0
MRPL46	1007	-2535.0
MRPL47	3173	-2238.0
MRPL48	-80	-1016.0
MRPL49	4766	-4287.0
MRPL50	3101	-1953.0
MRPL51	-389	-3858.0
MRPL52	-2314	-3091.0
MRPL54	-1999	-2160.0
MRPL55	1089	-4347.0
MRPL9	3433	-4876.0
MRPS10	-3085	-1917.0
MRPS11	283	-4954.0
MRPS12	-146	-4182.0
MRPS14	1795	-4725.0
MRPS15	1875	-4474.0
MRPS16	1205	-3440.0
MRPS17	-131	-2695.0
MRPS18A	469	-4626.0
MRPS18B	-1874	1045.0
MRPS18C	4378	-565.0
MRPS2	1441	-2634.0
MRPS22	4380	-3998.0
MRPS23	1674	-4542.0
MRPS25	-3561	-4702.0
MRPS26	-613	-4421.0
MRPS27	563	-4117.0
MRPS28	1356	-3864.0
MRPS30	3469	-2182.0
MRPS31	3506	-3633.0
MRPS33	152	-2442.0
MRPS34	-3846	-4787.0
MRPS35	3107	-4493.0
MRPS36	-2713	-3917.0
MRPS5	-1175	-4430.0
MRPS6	-4466	1321.0
MRPS7	-1337	-1519.0
MRPS9	1405	-4915.0
MTFMT	-1455	-3600.0
MTIF2	1804	-3460.0
MTIF3	279	-4638.0
OXA1L	-2621	-3854.0
PTCD3	3483	-5093.0

---

---

Mitochondrial translation termination

Mitochondrial translation termination

metric	value
setSize	81
pMANOVA	2.71e-27
p.adjustMANOVA	2.57e-25
s.dist	0.673
s.human	0.156
s.mouse	-0.654
p.human	0.0154
p.mouse	2.28e-24

Top 20 genes

Gene	human	mouse
MRPL49	4766	-4287.0
GFM2	3817	-5108.0
MRPL44	4401	-4096.0
PTCD3	3483	-5093.0
MRPS22	4380	-3998.0
MRPL9	3433	-4876.0
MRPL16	3084	-4785.0
MRPL18	2996	-4773.0
MRPS35	3107	-4493.0
MRPL3	2973	-4380.0
MRPS31	3506	-3633.0
MRPL19	4079	-3047.0
MRPL15	2470	-4290.0
MRPL22	3353	-2865.0
MRPL30	3497	-2718.5
ERAL1	2608	-3520.0
MRPL11	2096	-4254.0
MRPL42	2106	-4149.0
MRPS14	1795	-4725.0
MRPS15	1875	-4474.0

Click HERE to show all gene set members

All member genes

	human	mouse
AURKAIP1	-2308	-3467.0
CHCHD1	-543	-4442.0
DAP3	-463	354.0
ERAL1	2608	-3520.0
GADD45GIP1	-2418	-4820.0
GFM2	3817	-5108.0
MRPL1	-1296	-3497.0
MRPL10	-2406	-4655.0
MRPL11	2096	-4254.0
MRPL12	-2657	-3987.0
MRPL13	346	-1087.0
MRPL14	-1702	-2175.0
MRPL15	2470	-4290.0
MRPL16	3084	-4785.0
MRPL17	1930	1614.0
MRPL18	2996	-4773.0
MRPL19	4079	-3047.0
MRPL2	-437	-3027.0
MRPL20	538	-2975.0
MRPL21	1691	-1652.0
MRPL22	3353	-2865.0
MRPL23	-3221	-3820.0
MRPL24	-1884	-4451.0
MRPL27	-1616	-4786.0
MRPL28	-272	-3004.0
MRPL3	2973	-4380.0
MRPL30	3497	-2718.5
MRPL32	3068	3537.0
MRPL34	-2189	-4967.0
MRPL35	810	-3808.0
MRPL36	-560	-3281.0
MRPL37	1607	-4204.0
MRPL38	371	-3781.0
MRPL39	2592	-2566.0
MRPL4	2953	-2793.0
MRPL40	-250	-1725.0
MRPL41	-4898	-4188.0
MRPL42	2106	-4149.0
MRPL43	-1445	-3568.0
MRPL44	4401	-4096.0
MRPL46	1007	-2535.0
MRPL47	3173	-2238.0
MRPL48	-80	-1016.0
MRPL49	4766	-4287.0
MRPL50	3101	-1953.0
MRPL51	-389	-3858.0
MRPL52	-2314	-3091.0
MRPL54	-1999	-2160.0
MRPL55	1089	-4347.0
MRPL9	3433	-4876.0
MRPS10	-3085	-1917.0
MRPS11	283	-4954.0
MRPS12	-146	-4182.0
MRPS14	1795	-4725.0
MRPS15	1875	-4474.0
MRPS16	1205	-3440.0
MRPS17	-131	-2695.0
MRPS18A	469	-4626.0
MRPS18B	-1874	1045.0
MRPS18C	4378	-565.0
MRPS2	1441	-2634.0
MRPS22	4380	-3998.0
MRPS23	1674	-4542.0
MRPS25	-3561	-4702.0
MRPS26	-613	-4421.0
MRPS27	563	-4117.0
MRPS28	1356	-3864.0
MRPS30	3469	-2182.0
MRPS31	3506	-3633.0
MRPS33	152	-2442.0
MRPS34	-3846	-4787.0
MRPS35	3107	-4493.0
MRPS36	-2713	-3917.0
MRPS5	-1175	-4430.0
MRPS6	-4466	1321.0
MRPS7	-1337	-1519.0
MRPS9	1405	-4915.0
MRRF	-2794	77.0
MTRF1L	1519	-4781.0
OXA1L	-2621	-3854.0
PTCD3	3483	-5093.0

---

---

Extracellular matrix organization

Extracellular matrix organization

metric	value
setSize	194
pMANOVA	6.78e-21
p.adjustMANOVA	5.97e-19
s.dist	0.365
s.human	-0.253
s.mouse	0.263
p.human	1.41e-09
p.mouse	3.11e-10

Top 20 genes

Gene	human	mouse
ITGA5	-4752	5495
CAPN6	-4926	4911
COL27A1	-5084	4742
ADAMTS1	-4587	4909
FURIN	-4221	4897
MUSK	-3722	5360
ITGA9	-5247	3691
CAPN2	-3411	5352
CAPN15	-4668	3749
DAG1	-5236	3304
NCAM1	-3954	4316
ADAMTS4	-3160	5232
PLOD3	-4317	3640
ADAM15	-3594	4277
ADAMTS14	-4689	3275
ITGA3	-5514	2747
P4HA1	-2952	5096
TGFB1	-3111	4516
SERPINH1	-3526	3984
SDC3	-4619	2991

Click HERE to show all gene set members

All member genes

	human	mouse
ACTN1	-676	4422
ADAM10	-1509	1096
ADAM12	652	5402
ADAM15	-3594	4277
ADAM17	2407	736
ADAM19	-4678	312
ADAM8	-2592	4767
ADAM9	345	2175
ADAMTS1	-4587	4909
ADAMTS14	-4689	3275
ADAMTS2	-2757	2163
ADAMTS4	-3160	5232
ADAMTS5	3535	-2077
ADAMTS9	-783	1775
AGRN	-4903	783
ASPN	4413	3579
BGN	-1474	4543
BMP1	-4975	1026
BMP2	-4256	1160
BMP4	332	2940
BSG	-2248	-3662
CAPN1	-5166	-3782
CAPN10	-2183	-939
CAPN15	-4668	3749
CAPN2	-3411	5352
CAPN3	-4821	-3881
CAPN5	-2631	674
CAPN6	-4926	4911
CAPN7	-525	-4652
CAPNS1	-1346	1517
CASK	2884	5285
CASP3	423	5421
CAST	-753	5304
CD151	-5391	-60
CD44	837	5375
CD47	-2184	997
COL11A1	2133	650
COL11A2	-2851	-670
COL12A1	1925	1275
COL13A1	-2327	865
COL14A1	842	2137
COL15A1	-170	2699
COL16A1	-2954	2712
COL18A1	-2902	3703
COL1A1	-1639	1801
COL1A2	-1712	1529
COL22A1	-4865	1512
COL23A1	-4644	-285
COL24A1	-5131	1347
COL27A1	-5084	4742
COL28A1	2530	-161
COL2A1	3651	-95
COL3A1	2974	3277
COL4A1	-4755	1270
COL4A2	-5035	827
COL4A3	-3831	-4180
COL4A4	-3022	-3438
COL4A5	-4320	-2713
COL5A1	-1557	3000
COL5A2	-3030	3957
COL5A3	-1554	4005
COL6A1	-1945	2783
COL6A2	-1836	2972
COL6A3	-119	3607
COL6A6	-2138	-1882
COL7A1	-3232	-2914
COL8A1	892	5306
COL8A2	-459	-50
COLGALT1	-3751	103
COLGALT2	-4470	-460
COMP	278	1463
CRTAP	-3864	2487
CTSB	-1198	-1439
CTSD	-4817	-2585
CTSK	2	2230
CTSS	-339	3969
CTSV	2209	1721
DAG1	-5236	3304
DCN	-1048	102
DDR1	-4782	1503
DDR2	-1956	1740
DMD	-2970	-997
DST	-1750	754
EFEMP1	1210	-849
EFEMP2	-4537	3037
ELN	-5058	2093
F11R	-2302	-3195
FBLN1	-1631	3121
FBLN2	-644	4144
FBLN5	1536	-705
FBN1	645	4136
FGF2	751	3502
FMOD	-329	1647
FN1	35	4381
FURIN	-4221	4897
HSPG2	-5351	1532
HTRA1	-2591	-2102
ICAM1	1056	41
ICAM2	-1505	-2453
ITGA1	1757	-1535
ITGA10	-1878	25
ITGA11	-1012	-3014
ITGA3	-5514	2747
ITGA4	-2878	-2673
ITGA5	-4752	5495
ITGA6	-1002	-4343
ITGA7	-4721	1723
ITGA8	4618	1960
ITGA9	-5247	3691
ITGAM	-2633	5000
ITGAV	-819	2947
ITGAX	-896	-49
ITGB1	956	5174
ITGB2	-107	4082
ITGB3	-488	5180
ITGB5	-2578	-4752
ITGB6	475	-2771
ITGB8	3244	-601
JAM2	-5328	-4015
JAM3	1283	-1980
LAMA2	-3799	1005
LAMA3	-1011	-1639
LAMA4	746	766
LAMA5	-5584	-201
LAMB1	-457	829
LAMB2	-4894	-176
LAMB3	-4991	-2671
LAMC1	-3224	3688
LAMC2	1351	5422
LAMC3	-1576	-3666
LOX	4095	4471
LOXL1	-1591	4735
LOXL2	-3057	3955
LOXL3	-1113	3385
LOXL4	560	2671
LRP4	-5165	-3860
LTBP1	-67	-343
LTBP3	-3176	134
LTBP4	-1682	2895
LUM	-1839	2563
MFAP1	4936	3030
MFAP2	81	1781
MFAP3	4062	4070
MFAP4	-759	1916
MFAP5	-121	4976
MMP11	-3283	2279
MMP14	-1691	2189
MMP15	-5152	-4337
MMP17	-2367	5101
MMP19	-168	5177
MMP2	-692	-606
MUSK	-3722	5360
NCAM1	-3954	4316
NCSTN	-2504	-846
NID1	-1264	895
NID2	180	-153
NTN4	-1261	-2609
P4HA1	-2952	5096
P4HA2	-3956	1886
P4HB	-2525	5054
PCOLCE	-621	3503
PCOLCE2	1740	-114
PDGFA	-4328	-2495
PDGFB	-606	1041
PHYKPL	-5050	-3365
PLEC	-5473	-38
PLOD1	-4688	1430
PLOD2	3530	5157
PLOD3	-4317	3640
PPIB	-430	4046
PRKCA	-2938	1125
PSEN1	2070	3570
PTPRS	-4613	-4065
PXDN	-1438	-1048
SDC1	-2046	1023
SDC2	1756	4994
SDC3	-4619	2991
SDC4	-2393	5425
SERPINE1	-211	5469
SERPINH1	-3526	3984
SH3PXD2A	-5069	170
SPARC	-2672	1436
SPP1	1162	2350
TGFB1	-3111	4516
TGFB2	4602	2406
TGFB3	-5326	1062
THBS1	762	5034
TIMP1	-1317	5467
TIMP2	-1886	1226
TNC	803	4982
TNXB	-65	3094
TRAPPC4	3239	-1319
VCAM1	2866	4602
VCAN	1679	5186

---

---

Translation

Translation

metric	value
setSize	222
pMANOVA	3.12e-20
p.adjustMANOVA	2.56e-18
s.dist	0.342
s.human	0.144
s.mouse	-0.31
p.human	0.000227
p.mouse	2.14e-15

Top 20 genes

Gene	human	mouse
MRPL49	4766	-4287
GFM1	4202	-4858
GFM2	3817	-5108
MRPL44	4401	-4096
PTCD3	3483	-5093
MRPS22	4380	-3998
MRPL9	3433	-4876
SEC61A2	4702	-3506
MARS2	4685	-3490
YARS2	4860	-3192
HARS2	4723	-3250
MRPL16	3084	-4785
MRPL18	2996	-4773
EIF2B2	4162	-3424
MRPS35	3107	-4493
MRPL3	2973	-4380
MRPS31	3506	-3633
MRPL19	4079	-3047
FARS2	2754	-3851
MRPL15	2470	-4290

Click HERE to show all gene set members

All member genes

	human	mouse
AARS2	-2670	-4760.0
AIMP1	1421	-2607.0
AIMP2	-2727	1101.0
APEH	-3390	-2532.0
AURKAIP1	-2308	-3467.0
CARS2	-2768	-2892.0
CHCHD1	-543	-4442.0
DAP3	-463	354.0
DARS2	1640	-4113.0
DDOST	320	4978.0
EARS2	-2493	-453.0
EEF1A1	-2150	3461.0
EEF1A2	-5434	-4049.0
EEF1B2	937	178.0
EEF1D	-3342	-3067.0
EEF1E1	2843	3832.0
EEF2	-2853	740.0
EIF2B1	-7	2960.0
EIF2B2	4162	-3424.0
EIF2B3	-3592	-1265.0
EIF2B4	-180	-1110.0
EIF2B5	-2081	1803.0
EIF2S1	4274	2575.0
EIF2S2	3602	2576.0
EIF3A	1850	-1503.0
EIF3B	3746	3880.0
EIF3C	-2296	-1950.0
EIF3D	887	4301.0
EIF3E	2511	4061.0
EIF3F	661	460.0
EIF3G	426	-2061.0
EIF3H	4812	-1942.0
EIF3I	3218	1309.0
EIF3K	-3351	-3295.0
EIF3L	-16	1864.0
EIF3M	4410	-434.0
EIF4A1	2916	5463.0
EIF4A2	1360	849.0
EIF4B	993	-2864.0
EIF4E	2892	2481.0
EIF4EBP1	-1049	-251.0
EIF4G1	-2988	-962.0
EIF4H	1149	3489.0
EIF5	1898	5234.0
EIF5B	4665	-1984.0
ERAL1	2608	-3520.0
ETF1	3946	5448.0
FARS2	2754	-3851.0
FARSA	-1804	-1872.0
FARSB	3345	4275.0
FAU	2272	2649.0
GADD45GIP1	-2418	-4820.0
GFM1	4202	-4858.0
GFM2	3817	-5108.0
GSPT1	1495	2169.0
HARS2	4723	-3250.0
IARS2	1951	-5054.0
LARS2	2120	-2275.0
MARS2	4685	-3490.0
MRPL1	-1296	-3497.0
MRPL10	-2406	-4655.0
MRPL11	2096	-4254.0
MRPL12	-2657	-3987.0
MRPL13	346	-1087.0
MRPL14	-1702	-2175.0
MRPL15	2470	-4290.0
MRPL16	3084	-4785.0
MRPL17	1930	1614.0
MRPL18	2996	-4773.0
MRPL19	4079	-3047.0
MRPL2	-437	-3027.0
MRPL20	538	-2975.0
MRPL21	1691	-1652.0
MRPL22	3353	-2865.0
MRPL23	-3221	-3820.0
MRPL24	-1884	-4451.0
MRPL27	-1616	-4786.0
MRPL28	-272	-3004.0
MRPL3	2973	-4380.0
MRPL30	3497	-2718.5
MRPL32	3068	3537.0
MRPL34	-2189	-4967.0
MRPL35	810	-3808.0
MRPL36	-560	-3281.0
MRPL37	1607	-4204.0
MRPL38	371	-3781.0
MRPL39	2592	-2566.0
MRPL4	2953	-2793.0
MRPL40	-250	-1725.0
MRPL41	-4898	-4188.0
MRPL42	2106	-4149.0
MRPL43	-1445	-3568.0
MRPL44	4401	-4096.0
MRPL46	1007	-2535.0
MRPL47	3173	-2238.0
MRPL48	-80	-1016.0
MRPL49	4766	-4287.0
MRPL50	3101	-1953.0
MRPL51	-389	-3858.0
MRPL52	-2314	-3091.0
MRPL54	-1999	-2160.0
MRPL55	1089	-4347.0
MRPL9	3433	-4876.0
MRPS10	-3085	-1917.0
MRPS11	283	-4954.0
MRPS12	-146	-4182.0
MRPS14	1795	-4725.0
MRPS15	1875	-4474.0
MRPS16	1205	-3440.0
MRPS17	-131	-2695.0
MRPS18A	469	-4626.0
MRPS18B	-1874	1045.0
MRPS18C	4378	-565.0
MRPS2	1441	-2634.0
MRPS22	4380	-3998.0
MRPS23	1674	-4542.0
MRPS25	-3561	-4702.0
MRPS26	-613	-4421.0
MRPS27	563	-4117.0
MRPS28	1356	-3864.0
MRPS30	3469	-2182.0
MRPS31	3506	-3633.0
MRPS33	152	-2442.0
MRPS34	-3846	-4787.0
MRPS35	3107	-4493.0
MRPS36	-2713	-3917.0
MRPS5	-1175	-4430.0
MRPS6	-4466	1321.0
MRPS7	-1337	-1519.0
MRPS9	1405	-4915.0
MRRF	-2794	77.0
MTFMT	-1455	-3600.0
MTIF2	1804	-3460.0
MTIF3	279	-4638.0
MTRF1L	1519	-4781.0
N6AMT1	-2374	-2711.0
NARS2	2046	-3967.0
OXA1L	-2621	-3854.0
PARS2	2650	514.0
PPA1	1522	-1816.0
PPA2	-163	-3735.0
PTCD3	3483	-5093.0
RARS2	-56	-1764.0
RPL10	-3902	3923.0
RPL11	-2249	-1971.0
RPL14	433	-875.0
RPL18	-1782	448.0
RPL18A	-2969	-320.0
RPL19	-502	-1379.0
RPL22	1231	-3446.0
RPL22L1	3380	2374.0
RPL23	-115	-2882.0
RPL26	1047	696.0
RPL28	-391	-1891.0
RPL3	-786	5412.0
RPL30	286	-3056.0
RPL31	-595	2894.0
RPL32	-367	-950.0
RPL34	1447	-1314.0
RPL35A	812	-1471.0
RPL36A	1261	-1408.0
RPL37	-715	-1311.0
RPL37A	-1043	554.0
RPL38	231	-953.0
RPL3L	-5212	-4614.0
RPL4	-522	-571.0
RPL5	1206	3360.0
RPL7	1440	-1894.0
RPL8	-2775	-928.0
RPLP2	-2469	-3389.0
RPN1	768	-2883.0
RPN2	497	2665.0
RPS11	-1582	-458.0
RPS12	-318	1501.0
RPS13	1131	-1994.0
RPS14	-1412	122.0
RPS15	-1799	-1082.0
RPS15A	-704	-237.0
RPS16	-1828	2010.0
RPS18	-974	-1404.0
RPS19	-2045	-882.0
RPS20	-1844	1712.0
RPS21	-1536	-2810.0
RPS23	-68	-749.0
RPS24	256	-1505.0
RPS26	-282	-1421.0
RPS27A	783	-2165.0
RPS27L	-616	-69.0
RPS29	-1140	-1275.0
RPS3	-544	116.0
RPS4X	83	97.0
RPS5	-1577	935.0
RPS6	-245	1237.0
RPS8	-1593	-1231.0
RPS9	-1107	-2477.0
SARS2	-3583	-4897.0
SEC11A	-665	1703.0
SEC11C	1866	2265.0
SEC61A1	1613	5134.0
SEC61A2	4702	-3506.0
SEC61G	2374	-461.0
SPCS1	2081	-1989.0
SPCS2	2182	3022.0
SPCS3	3092	3472.0
SRP14	2888	-3550.0
SRP19	4688	-1030.0
SRP54	4760	1591.0
SRP68	-940	1446.0
SRP72	4000	396.0
SRP9	2308	-978.0
SRPRB	-1164	3998.0
SSR1	2031	4289.0
SSR2	2578	4998.0
SSR3	4112	3123.0
SSR4	-2063	-1234.0
TARS2	-526	-3362.0
TRAM1	3799	4576.0
TSFM	1964	-4406.0
TUFM	-2588	-4806.0
VARS2	-2639	-4749.0
WARS2	-890	1542.0
YARS2	4860	-3192.0

---

---

Muscle contraction

Muscle contraction

metric	value
setSize	120
pMANOVA	1.32e-19
p.adjustMANOVA	1.02e-17
s.dist	0.502
s.human	-0.493
s.mouse	-0.0934
p.human	1.12e-20
p.mouse	0.0781

Top 20 genes

Gene	human	mouse
ATP1A2	-5569	-4880
PAK1	-5419	-4706
ATP2A1	-5479	-4435
CACNB1	-5285	-4156
KCNJ12	-5368	-4083
CAMK2A	-5527	-3819
PRKACA	-4691	-4303
SCN4A	-5601	-3596
CACNG6	-5276	-3813
TNNI2	-4910	-4080
MYLPF	-4355	-4535
ATP2B3	-4422	-4436
MYL3	-3976	-4930
NPR2	-3578	-5047
TPM1	-4592	-3836
DMPK	-5518	-3180
TNNT3	-4247	-4046
TCAP	-5032	-3354
MYBPC2	-5048	-3336
MYL2	-4849	-3472

Click HERE to show all gene set members

All member genes

	human	mouse
ABCC9	-3151	-3503
ACTA2	-3819	4068
ACTN2	-3104	-1086
AHCYL1	-3386	2570
AKAP9	-573	-4367
ANXA1	537	4783
ANXA2	-4123	5407
ANXA6	-5097	4577
ASPH	-3277	-3019
ATP1A1	-4096	5364
ATP1A2	-5569	-4880
ATP1A3	206	3197
ATP1B1	2576	-3831
ATP1B3	-598	2812
ATP2A1	-5479	-4435
ATP2A2	-2976	2104
ATP2A3	-4467	1381
ATP2B1	2034	3586
ATP2B3	-4422	-4436
ATP2B4	-2762	2239
CACNA1C	-762	1596
CACNB1	-5285	-4156
CACNG6	-5276	-3813
CALD1	3357	3895
CALM1	-4464	1071
CAMK2A	-5527	-3819
CAMK2B	-5497	-2856
CAMK2D	-2223	5094
CAMK2G	-2097	-4184
CAV3	-5286	1576
DES	-4740	4011
DMD	-2970	-997
DMPK	-5518	-3180
DYSF	-4799	5068
FGF11	-3896	-1457
FGF13	-844	801
FXYD1	-2722	-4881
GUCY1B3	4506	-4823
HIPK1	4147	4913
HIPK2	-4312	2753
ITGA1	1757	-1535
ITGB5	-2578	-4752
ITPR1	4903	1106
ITPR2	1242	53
ITPR3	-3631	-2403
KAT2B	-3340	-2881
KCNE4	-764	2931
KCNH2	-3531	429
KCNJ11	-5488	339
KCNJ12	-5368	-4083
KCNJ2	-4246	-3576
KCNK2	-480	980
KCNK6	-1417	2337
KCNQ1	-3887	1452
LMOD1	-4937	1525
MYBPC1	-4465	-2024
MYBPC2	-5048	-3336
MYH3	-4216	2204
MYH6	-4746	1464
MYH8	-4002	4637
MYL1	-1989	-784
MYL10	-3328	-1133
MYL12A	84	5497
MYL12B	1563	594
MYL2	-4849	-3472
MYL3	-3976	-4930
MYL4	-4626	2885
MYL6	-3628	1353
MYL6B	-4219	-707
MYL9	-4777	-1049
MYLK	-3879	1507
MYLPF	-4355	-4535
NEB	-2805	-2418
NOS1	-4260	-3419
NPR2	-3578	-5047
ORAI2	936	56
PAK1	-5419	-4706
PAK2	1525	5331
PLN	-2060	880
PRKACA	-4691	-4303
PXN	-4750	1059
RANGRF	-4019	-2978
RYR1	-5289	-1224
RYR3	-2435	129
SCN1B	-4899	-3023
SCN2A	544	1112
SCN2B	-4268	-3399
SCN3A	2439	4272
SCN3B	-3892	3499
SCN4A	-5601	-3596
SCN5A	-5309	3639
SLC8A1	754	-1425
SLC8A3	-5477	-1832
SORBS1	-3741	-3041
SORBS3	-5064	-2898
SRI	-4069	3732
STIM1	-3417	-3701
TCAP	-5032	-3354
TLN1	-3918	3071
TMOD1	-5339	-2629
TMOD2	-2848	1289
TMOD3	376	681
TNNC1	-4638	-1320
TNNC2	-4220	-3878
TNNI1	-3744	162
TNNI2	-4910	-4080
TNNT1	-4248	-1804
TNNT2	-3984	1022
TNNT3	-4247	-4046
TPM1	-4592	-3836
TPM2	-3443	-4155
TPM3	-3868	727
TPM4	191	4980
TRDN	-3364	-4574
TRIM72	-5057	-409
TRPC1	1744	1215
TTN	3968	-2380
VCL	-4538	5383
VIM	-3027	5076
WWTR1	-2503	3401

---

---

Complex I biogenesis

Complex I biogenesis

metric	value
setSize	52
pMANOVA	2.28e-19
p.adjustMANOVA	1.65e-17
s.dist	0.765
s.human	-0.196
s.mouse	-0.739
p.human	0.0145
p.mouse	2.74e-20

Top 20 genes

Gene	human	mouse
ACAD9	-4578	-4327
NDUFB7	-4222	-4592
NDUFS7	-4871	-3791
NDUFS8	-4325	-4250
NDUFV1	-4226	-4284
NDUFB8	-3020	-4892
NDUFA3	-3805	-3788
NDUFB10	-3373	-4176
NDUFS3	-3567	-3762
NDUFAF3	-3581	-3648
MT-ND5	-3244	-3936
NDUFB2	-3732	-3330
NDUFS2	-3026	-4010
NDUFV3	-2378	-4769
NDUFA9	-2868	-3934
NDUFAF6	-2555	-4169
ECSIT	-2655	-4003
NDUFA13	-2253	-4458
NDUFB11	-2103	-4410
NDUFA10	-1955	-4567

Click HERE to show all gene set members

All member genes

	human	mouse
ACAD9	-4578	-4327
ECSIT	-2655	-4003
MT-ND1	-353	-4097
MT-ND2	-1120	-4098
MT-ND4	-2086	-3521
MT-ND5	-3244	-3936
MT-ND6	816	-5003
NDUFA1	-737	-4064
NDUFA10	-1955	-4567
NDUFA11	-1033	-3018
NDUFA12	-1315	-3437
NDUFA13	-2253	-4458
NDUFA2	-1290	-3394
NDUFA3	-3805	-3788
NDUFA5	534	-4100
NDUFA6	-77	-4563
NDUFA7	-465	-4072
NDUFA8	-602	-3874
NDUFA9	-2868	-3934
NDUFAB1	1151	-3286
NDUFAF1	1175	-4667
NDUFAF2	3504	-3035
NDUFAF3	-3581	-3648
NDUFAF4	3740	-1490
NDUFAF5	29	-2432
NDUFAF6	-2555	-4169
NDUFAF7	2971	-1191
NDUFB10	-3373	-4176
NDUFB11	-2103	-4410
NDUFB2	-3732	-3330
NDUFB3	852	-4452
NDUFB4	-311	-2945
NDUFB5	-2039	-3251
NDUFB6	928	-2670
NDUFB7	-4222	-4592
NDUFB8	-3020	-4892
NDUFB9	-996	-4847
NDUFC1	-664	-3623
NDUFC2	34	-4249
NDUFS1	-1544	-4861
NDUFS2	-3026	-4010
NDUFS3	-3567	-3762
NDUFS4	-1690	-4308
NDUFS5	-1235	-4521
NDUFS6	-1332	-4239
NDUFS7	-4871	-3791
NDUFS8	-4325	-4250
NDUFV1	-4226	-4284
NDUFV3	-2378	-4769
NUBPL	-1541	-1280
TIMMDC1	213	-2918
TMEM126B	1024	1865

---

---

Protein localization

Protein localization

metric	value
setSize	136
pMANOVA	1.08e-18
p.adjustMANOVA	7.39e-17
s.dist	0.453
s.human	-0.0458
s.mouse	-0.451
p.human	0.358
p.mouse	1.19e-19

Top 20 genes

Gene	human	mouse
CRAT	-5334	-4863.0
SLC25A12	-5347	-4761.0
ABCD1	-5486	-3968.0
UBL4A	-5261	-4125.0
CAT	-4828	-4447.0
ECH1	-4845	-4247.0
PEX6	-4530	-4525.0
ECI2	-4454	-4351.0
CHCHD10	-4902	-3931.0
DDO	-3779	-4874.0
GSTK1	-4345	-4224.0
PHYH	-4170	-4330.0
TAZ	-3604	-4956.0
CYC1	-4147	-4292.0
PEX10	-3687	-4811.0
ACO2	-3822	-4534.0
IDH3G	-4178	-3714.0
NUDT7	-3378	-4518.0
NDUFB8	-3020	-4892.0
ACOT2	-2912	-4940.5

Click HERE to show all gene set members

All member genes

	human	mouse
ABCD1	-5486	-3968.0
ABCD2	-100	-3636.0
ABCD3	3813	-4685.0
ACBD5	-1208	-1600.0
ACO2	-3822	-4534.0
ACOT2	-2912	-4940.5
ACOT8	-957	-2654.0
ACOX1	3989	2503.0
ACOX3	-2027	-4032.0
AGPS	3505	2944.0
ALDH3A2	-71	1336.0
AMACR	4160	-4700.0
APP	-2792	154.0
ATAD1	2365	-4285.0
BAG6	-4173	-1441.0
BCS1L	-1023	-4605.0
CAMLG	2314	-890.0
CAT	-4828	-4447.0
CHCHD10	-4902	-3931.0
CHCHD2	446	-3053.0
CHCHD3	123	-3496.0
CHCHD4	-2167	-2361.0
CHCHD5	-2111	-2033.0
CHCHD7	2643	-1066.0
CMC2	3597	-4660.0
COA4	-3800	-973.0
COA6	4111	-3650.0
COQ2	-1700	-3133.0
COX17	-2094	-1938.0
COX19	3053	2889.0
CRAT	-5334	-4863.0
CROT	3694	4862.0
CS	3653	-4328.0
CYB5A	-1123	-3119.0
CYC1	-4147	-4292.0
DDO	-3779	-4874.0
DECR2	-2311	1855.0
DHRS4	-691	-4298.5
DNAJC19	1118	-4186.0
ECH1	-4845	-4247.0
ECI2	-4454	-4351.0
EHHADH	-1005	-906.0
EMD	-651	533.0
EPHX2	-2227	-4973.0
FIS1	-3503	-3589.0
FXN	-2179	-3293.0
GDAP1	-332	-4533.0
GET4	-939	2048.0
GFER	-3119	-1243.0
GNPAT	-1893	-3964.0
GRPEL1	-2346	-2045.0
GRPEL2	1127	1067.0
GSTK1	-4345	-4224.0
HACL1	4520	-3057.0
HMGCL	-4130	-3323.0
HMOX1	-2843	4573.0
HSCB	-134	-1814.0
HSD17B4	689	-4557.0
HSPA9	2342	-3484.0
HSPD1	-855	-3145.0
IDE	-1349	-2216.0
IDH1	1160	-4779.0
IDH3G	-4178	-3714.0
LDHD	-5163	-2192.0
LONP2	266	-2522.0
MLYCD	-2169	-5081.0
MTX1	2018	-1987.0
MTX2	52	-2397.0
NDUFB8	-3020	-4892.0
NUDT19	-2286	-2667.0
NUDT7	-3378	-4518.0
PAM16	-2464	-2969.0
PAOX	223	873.0
PECR	-1213	-2572.0
PEX1	3050	-2706.0
PEX10	-3687	-4811.0
PEX11B	-1423	-3247.0
PEX12	-516	3103.0
PEX13	3575	-2162.0
PEX14	-3967	1772.0
PEX16	-1262	-2030.0
PEX19	-1861	-4481.0
PEX2	1241	171.0
PEX26	1745	4428.0
PEX3	3593	-1480.0
PEX5	-3479	1145.0
PEX6	-4530	-4525.0
PEX7	-2837	-3288.0
PHYH	-4170	-4330.0
PITRM1	582	-1790.0
PMPCA	-92	-3017.0
PMPCB	-832	-4741.0
PRNP	2908	5455.0
PXMP2	-1741	-4990.0
PXMP4	-776	-4742.0
RPS27A	783	-2165.0
SAMM50	1141	-4536.0
SCP2	-862	-4948.0
SEC61G	2374	-461.0
SERP1	2541	5409.0
SGTA	487	-3071.0
SLC25A12	-5347	-4761.0
SLC25A13	4283	2507.0
SLC25A17	4134	3081.0
SLC25A4	-1327	-4427.0
STX1A	-411	1598.0
STX5	1631	4052.0
TAZ	-3604	-4956.0
TIMM10	179	-2702.0
TIMM10B	4307	-4902.0
TIMM13	-3591	-2117.0
TIMM17A	2548	-4167.0
TIMM17B	-3141	-2749.0
TIMM21	1825	-4898.0
TIMM22	1561	-3223.0
TIMM44	-1151	-5068.0
TIMM50	987	-2561.0
TIMM8B	-658	-3816.0
TIMM9	690	-3965.0
TOMM20	2711	101.0
TOMM22	2828	-2447.0
TOMM40	4211	-1560.0
TOMM5	2707	-4232.0
TOMM7	-1885	-3378.0
TYSND1	-1757	-1399.0
UBC	2672	3877.0
UBE2D1	-1588	-4657.0
UBE2D2	-1986	1804.0
UBE2D3	1424	5192.0
UBE2J2	383	-532.0
UBL4A	-5261	-4125.0
USP9X	1458	-295.0
VAMP2	-3293	-1899.0
VAPA	2838	2825.0
VDAC1	-2909	-4782.0
ZFAND6	2251	-4827.0

---

---

Gene expression (Transcription)

Gene expression (Transcription)

metric	value
setSize	997
pMANOVA	1.17e-17
p.adjustMANOVA	7.57e-16
s.dist	0.177
s.human	0.166
s.mouse	0.0625
p.human	4.98e-18
p.mouse	0.00113

Top 20 genes

Gene	human	mouse
TAF4B	4967	5489
CTR9	4954	5471
CLP1	4787	5453
DDX21	4868	5307
SUPT6H	4807	5334
TAF7	4717	5281
CDK12	4852	5130
MED13	4601	5355
ELL2	4753	5145
RYBP	4895	4848
GTF2B	4276	5493
EAF1	4531	5165
NUP98	4235	5486
CDC40	4670	4950
TAF1D	4278	5314
PLK2	4764	4721
NFYA	4965	4520
GTF2F1	4999	4439
RBM14	4731	4683
ALYREF	5008	4414

Click HERE to show all gene set members

All member genes

	human	mouse
AAAS	-3476	40.0
ABCA6	-135	-3581.0
ABL1	-4533	1377.0
ACTB	940	5427.0
ACTL6A	4077	2128.0
AEBP2	3975	4113.0
AFF4	3610	4555.0
AGO1	2453	283.0
AGO2	-4001	3296.0
AGO3	2529	188.0
AGO4	-3006	-1611.0
AIFM2	-4217	-3792.0
AKT1	-4954	1242.0
AKT2	-4057	-3488.0
AKT3	1343	2419.0
ALYREF	5008	4414.0
ANAPC1	572	-470.0
ANAPC10	1974	2927.0
ANAPC11	-3265	-2502.0
ANAPC15	-3393	1658.0
ANAPC16	-3612	-3229.0
ANAPC2	-2185	-1142.0
ANAPC4	-720	-3761.0
ANAPC5	1284	-3105.0
ANAPC7	1595	882.0
APAF1	-3469	3979.0
APOE	-1428	-1396.0
AR	-4468	-4062.0
ARID1A	-1226	4164.0
ARID1B	-3838	4159.0
ARID2	2812	1097.0
ARID3A	-4418	2066.0
ARID4B	4763	142.0
ASH2L	-45	-4934.0
ASUN	1039	3366.0
ATAD2	4225	2993.0
ATF2	3130	2882.0
ATM	1449	-3358.0
ATP1B4	-5072	3790.0
ATR	1983	1782.0
ATXN3	4003	1979.0
AURKA	3811	-2443.0
AUTS2	-4742	3797.0
AXIN1	-730	3755.0
BANP	2381	4757.0
BAX	-1846	4611.0
BAZ1B	3725	-1622.0
BAZ2A	4001	3209.0
BCDIN3D	1529	2545.0
BCL2L11	-4974	234.0
BCL6	-5018	1298.0
BDNF	1086	5317.0
BDP1	4285	2616.0
BID	-4951	3351.0
BLM	1103	4665.0
BMI1	3349	3812.0
BMP2	-4256	1160.0
BNIP3L	3835	-2712.0
BRD1	-2076	190.0
BRD2	4330	4714.0
BRD7	221	-3080.0
BRF1	-5470	-555.0
BRF2	-1971	313.0
BRPF1	3074	4211.0
BRPF3	3668	4607.0
BTG1	3137	5099.0
BTG2	-5444	5528.0
CALM1	-4464	1071.0
CAMK2A	-5527	-3819.0
CAMK2B	-5497	-2856.0
CAMK2D	-2223	5094.0
CAMK2G	-2097	-4184.0
CARM1	-4331	-1463.0
CASC3	9	2673.0
CASP1	-1298	1115.0
CASP2	2946	-2821.0
CASP6	4829	-2899.0
CAT	-4828	-4447.0
CAV1	-646	-1312.0
CBFB	3786	-2549.0
CBX2	2360	-1727.0
CBX4	3208	4922.0
CBX5	1538	1494.0
CBX6	-482	1921.0
CBX8	-917	-1786.0
CCNA2	3061	2333.0
CCNC	4650	3631.0
CCND1	757	1643.0
CCND2	225	2762.0
CCND3	786	1243.0
CCNE1	4388	4060.0
CCNE2	4667	-521.0
CCNG1	1596	-2539.0
CCNG2	-2635	-1516.0
CCNH	3825	-1939.0
CCNK	3139	-346.0
CCNT1	4896	309.0
CCNT2	4381	-4634.0
CDC16	86	-1235.0
CDC23	3850	1048.0
CDC26	2750	2001.0
CDC27	665	3905.0
CDC40	4670	4950.0
CDC7	2421	3646.0
CDC73	2659	3408.0
CDK1	1580	3204.0
CDK12	4852	5130.0
CDK13	4123	3295.0
CDK2	849	2902.0
CDK4	703	2603.0
CDK5	-1007	-2874.0
CDK6	1090	2660.0
CDK7	1571	326.0
CDK8	623	-1266.0
CDK9	-1348	4755.0
CDKN1A	-4927	3046.0
CDKN1B	-3284	-2637.0
CDKN2B	-2827	-832.0
CEBPB	-4699	-3003.0
CENPJ	1720	200.0
CHD3	-3721	-2281.0
CHD4	-4283	1724.0
CHEK2	1311	-33.0
CHM	1406	544.0
CHTOP	-574	2577.0
CITED2	770	4652.0
CITED4	-4657	-5028.0
CLDN5	-2058	-4160.0
CLP1	4787	5453.0
CNOT1	4456	1508.0
CNOT10	1314	-2583.0
CNOT11	2698	1032.0
CNOT2	3263	518.0
CNOT3	857	2288.0
CNOT4	2350	1422.0
CNOT6	1509	4740.0
CNOT6L	-2201	3671.0
CNOT7	1298	2117.0
CNOT8	3240	-3842.0
COL1A1	-1639	1801.0
COX11	-2860	-2700.0
COX14	-2772	-4676.0
COX16	-2259	-2674.0
COX18	-554	-2459.0
COX19	3053	2889.0
COX20	1104	-3676.0
COX4I1	-2357	-3606.0
COX5A	-2511	-4214.0
COX5B	-2559	-4822.0
COX6A1	2259	-1583.0
COX6B1	-2231	-3407.0
COX6C	-18	-3754.0
COX7B	144	-2853.0
COX7C	-1495	-3356.0
COX8A	-4337	-3691.0
CPSF1	-3670	977.0
CPSF2	-922	-1111.0
CPSF3	1953	2237.0
CPSF3L	-1923	1313.0
CPSF4	862	4202.0
CPSF7	407	-1612.0
CRADD	-2847	-4359.0
CRCP	1806	-1063.0
CREB1	2179	-1920.0
CREBBP	1506	4134.0
CSNK2A1	1796	-2551.0
CSNK2A2	2123	2667.0
CSNK2B	1917	-1746.0
CSTF1	2216	1705.0
CSTF2	1437	-1058.0
CSTF2T	2703	4379.0
CSTF3	-2793	4119.0
CTDP1	2071	4946.0
CTGF	-275	4418.0
CTNNB1	1714	2956.0
CTR9	4954	5471.0
CTSK	2	2230.0
CTSV	2209	1721.0
CUL1	-3121	-833.0
DAXX	4449	3854.0
DDB2	-5027	-3642.0
DDIT3	-1718	-2205.0
DDIT4	-2764	4387.0
DDX21	4868	5307.0
DDX39A	3417	-377.0
DDX39B	984	839.0
DEK	2056	4276.0
DGCR8	-4643	2467.0
DHX38	2857	440.0
DICER1	1824	2697.0
DLL1	-3980	-2417.0
DNA2	37	3262.0
DNMT1	-461	4223.0
DNMT3A	-3771	-1402.0
DNMT3B	-1360	-1803.0
DPY30	3923	-1391.0
DROSHA	-694	-2421.0
DYRK2	-2000	-210.0
E2F1	-529	4887.0
E2F4	-439	4952.0
E2F5	-249	1172.0
E2F6	650	-3961.0
E2F7	512	3554.0
E2F8	-5620	3457.0
EAF1	4531	5165.0
EED	3304	3108.0
EGFR	424	2978.0
EHMT1	-76	902.0
EHMT2	-520	-2448.0
EIF4A3	4491	2615.0
ELF1	4399	4183.0
ELF2	-2817	-2633.0
ELL	-3990	3539.0
ELL2	4753	5145.0
EP300	3403	2309.0
EPC1	362	4609.0
ERBB2	-5511	494.0
ERCC2	824	4319.0
ERCC3	473	3200.0
ERCC6	4227	3642.0
ESR1	-1770	-2342.0
ESRRA	-4570	-4658.0
ESRRB	-2671	2642.0
ESRRG	-4340	-4075.0
EZH2	4698	4282.0
FANCC	-709	-911.0
FAS	-4771	2003.0
FBXO32	-4380	-4503.0
FBXW7	-886	1644.0
FIP1L1	3587	3058.0
FKBP5	750	-1102.0
FOS	1865	5350.0
FOXO1	-432	3792.0
FOXO3	-42	2244.0
FOXO4	-3493	-3713.0
FOXO6	-4157	-792.0
FYTTD1	3374	4804.0
FZR1	-1244	3161.0
G6PD	579	5116.0
GADD45A	514	-1269.0
GAMT	-5400	-2080.0
GATAD2A	-975	5411.0
GATAD2B	304	4882.0
GLI2	-1180	3016.0
GLI3	3731	3520.0
GLS	4937	1394.0
GPAM	1132	-5046.0
GPI	-5210	-4750.0
GPS2	2002	-25.0
GSK3B	897	4692.0
GSR	-2148	848.0
GTF2A1	4730	4204.0
GTF2A2	4648	-2956.0
GTF2B	4276	5493.0
GTF2E1	2188	896.0
GTF2E2	2041	-136.0
GTF2F1	4999	4439.0
GTF2F2	4067	5047.0
GTF2H1	3886	647.0
GTF2H2	4419	-2426.5
GTF2H3	-1925	-664.0
GTF2H5	-878	-3245.0
GTF3A	-2151	-238.0
GTF3C1	4242	-497.0
GTF3C3	-551	3067.0
GTF3C4	4066	3042.0
GTF3C5	-2194	936.0
GTF3C6	1008	9.0
H2AFX	2356	5181.0
HDAC10	-3116	762.0
HDAC11	-4482	3061.0
HDAC2	4386	-579.0
HDAC3	-178	-2363.0
HDAC4	-5061	-1561.0
HDAC5	-4921	3448.0
HDAC6	-4164	4690.0
HDAC7	-3827	-1671.0
HDAC8	209	-3383.0
HDAC9	-3759	4259.0
HES1	1695	-3299.0
HEY1	4826	210.0
HIPK1	4147	4913.0
HIPK2	-4312	2753.0
HIVEP3	-179	5045.0
HSP90AA1	3656	5525.0
HSPD1	-855	-3145.0
HTT	-70	5026.0
HUS1	2435	-1222.0
IGFBP3	2922	-1589.0
ING2	3993	-432.0
ING5	-2726	1628.0
INTS1	-1418	76.0
INTS10	4175	-3657.0
INTS12	3830	3259.0
INTS2	1193	2278.0
INTS3	1102	3704.0
INTS4	1878	1971.0
INTS5	1592	3335.0
INTS6	2200	5171.0
INTS7	2980	-1292.0
INTS8	1194	3742.0
INTS9	1494	3549.0
IPO8	-1526	-1728.0
IRAK1	-4351	-1420.0
ITCH	4319	2263.0
ITGA4	-2878	-2673.0
ITGA5	-4752	5495.0
ITGBL1	1885	986.0
IWS1	2510	3155.0
JAG1	3237	-943.0
JARID2	2339	2877.0
JMY	3902	1880.0
JUN	2469	5472.0
JUNB	-2593	4931.0
KAT2A	-5053	-3388.0
KAT2B	-3340	-2881.0
KAT5	447	1402.0
KAT6A	3849	3678.0
KCTD1	-2989	1558.0
KCTD15	-3871	-4794.0
KCTD6	2748	2384.0
KDM5B	4870	4075.0
KLF4	3126	4618.0
KMT2A	4833	3012.0
KMT2C	4070	-734.0
KMT2D	-1176	515.0
KMT2E	3381	2429.0
KRAS	3546	5146.0
KRBA1	-948	-5019.0
L3MBTL2	-956	1208.0
LAMTOR1	-800	-4509.0
LAMTOR2	-1715	-4532.0
LAMTOR3	3134	781.0
LAMTOR4	-2977	-641.0
LAMTOR5	636	-1109.0
LBR	2244	-878.0
LDB1	-5369	-3841.0
LEO1	2784	-714.0
LGALS3	1062	4689.0
LIFR	-994	-4778.0
LMO2	-1725	795.0
LRPPRC	1656	-4711.0
LSM10	-3826	1128.0
LSM11	-2895	-1506.0
MAF	-5349	-2988.0
MAGOH	4561	555.0
MAGOHB	2239	-1880.0
MAML1	2770	4362.0
MAML2	2681	2618.0
MAML3	-2079	1098.0
MAMLD1	-1668	2661.0
MAP2K6	1456	-4331.0
MAPK1	1988	-969.0
MAPK11	-3385	1370.0
MAPK14	-1562	-2824.0
MAPK3	-1024	4464.0
MAPKAP1	-405	1545.0
MAX	-2352	-1748.0
MBD2	3965	1131.0
MBD3	-3419	804.0
MDC1	841	2652.0
MDM2	3253	5156.0
MDM4	2051	-1866.0
MEAF6	1066	465.0
MECP2	-1705	-1071.0
MED1	4772	358.0
MED10	4087	2486.0
MED12	-2130	-467.0
MED13	4601	5355.0
MED14	2781	-2531.0
MED15	1233	5257.0
MED16	-2476	-4399.0
MED17	4255	2011.0
MED20	3604	-1597.0
MED23	3909	2920.0
MED24	-4786	-3269.0
MED25	2948	-1517.0
MED26	4038	2729.0
MED27	1227	3367.0
MED30	2307	-538.0
MED31	4638	-2680.0
MED4	4026	2219.0
MED6	4813	-1254.0
MED7	4316	1176.0
MED8	4163	-2286.0
MEF2C	-4610	2307.0
MEN1	1348	426.0
MET	-3529	4440.0
MGA	4502	-2399.0
MLH1	-1210	-3920.0
MLLT1	472	3521.0
MLLT3	3202	4762.0
MLST8	-3485	-1820.0
MNAT1	830	-3106.0
MOV10	-4127	-294.0
MSH2	4647	-4959.0
MSTN	-3974	3911.0
MT-CO1	-3167	-4401.0
MTA1	-4102	3149.0
MTA2	3682	-1298.0
MTA3	-2123	-1721.0
MTF2	4304	2311.0
MTOR	-1191	583.0
MYBBP1A	-833	3648.0
MYC	3994	185.0
MYL9	-4777	-1049.0
MYO1C	-4842	4663.0
NABP1	-3908	5475.0
NABP2	-279	-3357.0
NBN	1286	-1789.0
NCBP1	-1736	4720.0
NCBP2	4188	-2519.0
NCOR1	2625	-1011.0
NCOR2	-5167	-143.0
NDC1	1273	-322.0
NDRG1	-102	-267.0
NDUFA4	-393	-2605.0
NEDD4L	4279	95.0
NELFA	356	3429.0
NELFB	-1196	2017.0
NELFCD	1896	-2826.0
NELFE	-2178	3913.0
NFATC2	-3264	2685.0
NFIA	-4269	88.0
NFIB	267	1797.0
NFIC	-5402	-2226.0
NFIX	-5330	-3940.0
NFKB1	-4233	2228.0
NFYA	4965	4520.0
NFYB	1632	-4319.0
NFYC	-1444	-2678.0
NOC2L	1374	2996.0
NOP2	3472	5052.0
NOTCH1	-5460	-194.0
NOTCH3	-1225	2260.0
NR1D1	-5185	-383.0
NR1D2	1828	-3986.0
NR1H2	2288	2282.0
NR1H3	-3630	-3340.0
NR2C1	679	-3166.0
NR2C2	1579	-1470.0
NR2C2AP	2640	2320.0
NR2F1	-4439	3126.0
NR2F6	-4543	712.0
NR3C1	985	425.0
NR3C2	-1723	1466.0
NR4A1	-5560	-1228.0
NR4A2	-1651	-502.0
NR4A3	-4264	3637.0
NR6A1	-2345	2523.0
NRBF2	4966	-1758.0
NRBP1	2753	4086.0
NUAK1	-2765	3532.0
NUDT21	3626	432.0
NUP107	3232	3195.0
NUP133	889	-2580.0
NUP153	4762	4031.0
NUP155	4306	2897.0
NUP160	3998	2314.0
NUP188	2117	4593.0
NUP205	4438	3917.0
NUP214	3124	1845.0
NUP35	4571	2515.0
NUP37	-327	-873.0
NUP43	4562	193.0
NUP54	4508	4751.0
NUP85	3181	227.0
NUP88	1244	1407.0
NUP93	-1503	5229.0
NUP98	4235	5486.0
PAF1	2516	-2851.0
PARP1	-2423	278.0
PBRM1	3523	-980.0
PCBP4	-5523	-200.0
PCF11	-1597	-2273.0
PCGF5	1470	3462.0
PCGF6	1159	3236.0
PCNA	1329	5271.0
PDPK1	3443	3947.0
PERP	831	2446.0
PHAX	4729	-485.0
PHC1	456	3606.0
PHC2	-3719	5142.0
PHC3	3141	957.0
PHF1	-1798	3072.0
PHF19	-2605	1954.0
PHF20	819	949.0
PIN1	-3515	-3234.0
PINK1	-4060	-2958.0
PIP4K2A	4108	4105.0
PIP4K2C	2827	4009.0
PITX2	-5256	-2114.0
PIWIL2	773	-1696.0
PLAGL1	-4577	4670.0
PLK2	4764	4721.0
PLK3	-1003	3004.0
PLXNA4	-319	1224.0
PMAIP1	-4203	4118.0
PML	3338	3242.0
PMS2	806	-1226.0
POLDIP3	-1320	5061.0
POLR1A	-2441	-1633.0
POLR1B	3644	-1558.0
POLR1C	3643	3611.0
POLR1D	413	-1581.0
POLR1E	2918	4509.0
POLR2A	3861	5366.0
POLR2B	4509	-3401.0
POLR2C	4529	-4002.0
POLR2D	1669	3230.0
POLR2E	-667	148.0
POLR2G	89	4349.0
POLR2H	-3927	2213.0
POLR2I	-154	-2504.0
POLR2K	2480	-3599.0
POLR2L	-4314	-1126.0
POLR3A	4348	-1472.0
POLR3B	2547	-2035.0
POLR3C	4052	859.0
POLR3D	381	-435.0
POLR3E	1908	1839.0
POLR3F	4054	5048.0
POLR3G	1455	3939.0
POLR3GL	-1424	-4510.0
POLR3H	282	294.0
POLR3K	4716	-3380.0
POLRMT	-2205	-2936.0
POU2F1	3019	-1366.0
POU4F1	-1640	-4268.0
PPARA	-4997	-2863.0
PPARD	-4213	2330.0
PPARG	-1621	-2602.0
PPARGC1A	-4212	-4916.0
PPARGC1B	-5257	-2496.0
PPM1A	3438	-2375.0
PPM1D	1792	1169.0
PPP1R13B	3413	1613.0
PPP1R13L	-3554	3083.0
PPP2CA	4482	1672.0
PPP2CB	2458	2352.0
PPP2R1A	-4013	-681.0
PPP2R1B	3028	3194.0
PPP2R5C	-2508	-293.0
PRDM1	-50	-4190.0
PRDX1	605	2863.0
PRDX2	-5293	-3921.0
PRDX5	-3356	-3915.0
PRELID1	1651	4808.0
PRKAA1	3389	2399.0
PRKAA2	-3219	-2647.0
PRKAB1	3436	2257.0
PRKAB2	-2332	-3109.0
PRKACA	-4691	-4303.0
PRKAG1	2103	-3125.0
PRKAG2	-3237	502.0
PRKAG3	-5537	-2369.0
PRKCQ	-5095	-4724.0
PRKRA	1984	-1216.0
PRMT5	933	2092.0
PRMT6	2063	4057.0
PRR5	-837	161.0
PSMA1	2820	4043.0
PSMA3	3434	-1035.0
PSMA4	769	-1962.0
PSMA6	2199	-1657.0
PSMA7	-2980	-1038.0
PSMB1	954	-1037.0
PSMB10	-1800	-831.0
PSMB2	618	-67.0
PSMB4	-235	-559.0
PSMB5	-4113	-2597.0
PSMB6	-793	-1795.0
PSMB7	-831	-2699.0
PSMB8	-675	-2510.0
PSMB9	-1611	-3558.0
PSMC1	449	1146.0
PSMC2	-1311	3386.0
PSMC3	-2439	-1846.0
PSMC4	2724	-205.0
PSMC5	1212	-1680.0
PSMC6	-2520	3114.0
PSMD1	2619	3210.0
PSMD10	-1227	361.0
PSMD11	995	5504.0
PSMD12	3831	-462.0
PSMD13	821	532.0
PSMD14	-635	3746.0
PSMD2	-713	741.0
PSMD3	-3343	-354.0
PSMD4	-214	968.0
PSMD5	1807	4479.0
PSMD6	3537	-3784.0
PSMD7	-2329	410.0
PSMD8	-3171	4292.0
PSMD9	4204	-3586.0
PSME1	-2771	-2861.0
PSME2	-4085	-41.0
PSME3	3333	491.0
PSME4	1960	2319.0
PSMF1	683	-1768.0
PTEN	2797	4830.0
PTPN1	1531	4935.0
PTPN11	-1575	3105.0
PTPN4	-1408	5055.0
PTRF	-3348	1273.0
RABGGTA	-1231	-3826.0
RABGGTB	-945	-2383.0
RAD1	3205	3596.0
RAD17	2273	-1057.0
RAD50	306	-1413.0
RAD51	63	-3321.0
RAD51D	-876	399.0
RAD9A	-3149	-726.0
RAE1	4471	3078.0
RAN	2329	575.0
RANBP2	4470	-562.0
RARA	-5250	1555.0
RARB	-2995	-231.0
RARG	-4431	-1193.0
RB1	-2449	831.0
RBBP4	1072	728.0
RBBP5	4628	1244.0
RBBP7	-924	-1007.0
RBBP8	3047	3887.0
RBFOX1	-5102	-4362.0
RBL1	-1617	-993.0
RBL2	-242	-1988.0
RBM14	4731	4683.0
RBPJ	305	5264.0
RBX1	-733	-2400.0
RELA	1783	4454.0
RFC2	622	-3123.0
RFC3	2151	3463.0
RFC4	3542	-36.0
RFC5	1409	3702.0
RFFL	1079	-3627.0
RGCC	-1145	5503.0
RHEB	172	1360.0
RHNO1	-4573	-260.0
RICTOR	3562	1082.0
RING1	-1968	-3185.0
RMI1	4517	1974.0
RMI2	-2759	-2576.0
RNF111	3964	5247.0
RNF2	3038	4841.0
RNF34	3719	-1003.0
RNGTT	4414	-1456.0
RNMT	4864	3622.0
RNPS1	681	-2204.0
RORA	-5056	2669.0
RORC	-5248	-3275.0
RPA1	-1837	-2287.0
RPA2	2889	-3725.0
RPA3	2702	-4228.0
RPAP2	3147	-617.0
RPRD1A	-3380	-398.0
RPRD1B	2187	-2100.0
RPRD2	4039	1262.0
RPS27A	783	-2165.0
RPTOR	-4596	3929.0
RQCD1	4265	2047.0
RRAGA	2383	4039.0
RRAGB	-366	123.0
RRAGC	2091	1975.0
RRAGD	-4673	-3366.0
RRM2B	-887	-4516.0
RRN3	4557	3850.0
RRP8	4411	1645.0
RTF1	-2993	-2890.0
RUNX1	-2434	5228.0
RUNX2	85	247.0
RXRA	-5519	1619.0
RXRB	-1250	-4283.0
RXRG	-4055	-290.0
RYBP	4895	4848.0
SAP130	3375	3753.0
SAP18	4832	-868.0
SAP30	138	3914.0
SAP30BP	823	5221.0
SAP30L	-2519	-2301.0
SARNP	569	-1380.0
SATB2	3702	5476.0
SCMH1	-5007	-899.0
SCO1	3577	-27.0
SCO2	-1941	-3526.0
SEC13	730	938.0
SEH1L	1085	4110.0
SERPINE1	-211	5469.0
SESN1	-4227	1805.0
SESN2	-2604	5253.0
SESN3	4513	2809.0
SETD1A	2076	1573.0
SETD1B	-3010	3153.0
SF3B1	1067	5041.0
SGK1	1084	-4376.0
SIN3A	3397	2893.0
SIN3B	1030	316.0
SIRT1	4935	4355.0
SIRT3	-2752	-4933.0
SKI	-3187	2909.0
SKIL	1818	4329.0
SKP1	2028	-1286.0
SKP2	4205	4241.0
SLBP	2666	4469.0
SLC2A3	5004	2223.5
SLC38A9	969	1822.0
SLU7	4893	2372.0
SMAD1	-2920	5408.0
SMAD2	1125	5372.0
SMAD3	-3794	-3710.0
SMAD4	2354	2716.0
SMAD6	2009	-1203.0
SMAD7	-1051	3680.0
SMARCA2	-2904	-4911.0
SMARCA4	-3874	863.0
SMARCA5	4439	1177.0
SMARCB1	-474	548.0
SMARCC1	-4311	1930.0
SMARCC2	-3726	-172.0
SMARCD1	2718	3700.0
SMARCD2	319	1355.0
SMARCD3	-5399	-3136.0
SMARCE1	1364	2546.0
SMURF1	4443	-1337.0
SMURF2	1070	5348.0
SMYD2	-1305	-3228.0
SNAPC1	3749	4945.0
SNAPC2	3411	-464.0
SNAPC3	3029	1116.0
SNAPC4	363	1159.0
SNAPC5	-703	-3560.0
SNRPB	3761	-2577.0
SNRPD3	2384	-3590.0
SNRPE	3421	-1387.0
SNRPF	3777	-2345.0
SNRPG	3179	3068.0
SNW1	3618	4892.0
SOCS3	-283	4943.0
SOCS4	4713	1539.0
SOD2	-1568	-4837.0
SOX9	2175	5346.0
SP1	1787	967.0
SPP1	1162	2350.0
SRC	-3910	3763.0
SREBF1	-5230	273.0
SRRM1	2285	-2017.0
SRRT	4962	350.0
SRSF1	1871	-1493.0
SRSF11	3911	-1990.0
SRSF3	2586	1697.0
SRSF4	1929	3741.0
SRSF5	1997	-3060.0
SRSF6	1798	2387.0
SRSF7	3545	2132.0
SRSF9	3543	2675.0
SSB	4371	4056.0
SSRP1	1755	1765.0
SSU72	1324	-3343.0
STAT1	236	-3457.0
STEAP3	-5586	-4859.0
STK11	-4884	-3985.0
STUB1	-2898	-3668.0
SUDS3	3840	-2556.0
SUMO1	4213	-262.0
SUPT16H	3885	4417.0
SUPT4H1	3648	-1692.0
SUPT5H	1321	4377.0
SUPT6H	4807	5334.0
SURF1	-1748	-3290.0
SUV39H1	576	-1979.0
SUZ12	3871	4598.0
SYMPK	-3207	-1626.0
TACO1	651	-4903.0
TAF1	1708	4363.0
TAF10	-273	547.0
TAF11	2962	-1678.0
TAF12	3100	3716.0
TAF13	4749	1646.0
TAF1A	2375	-3181.0
TAF1B	3690	573.0
TAF1C	-1934	4398.0
TAF1D	4278	5314.0
TAF2	4591	3536.0
TAF3	4294	4087.0
TAF4	-1340	4027.0
TAF4B	4967	5489.0
TAF5	4309	1473.0
TAF6	-912	-885.0
TAF7	4717	5281.0
TAF8	2937	1493.0
TAF9B	1874	-618.0
TARBP2	1653	-2140.0
TBL1XR1	1876	528.0
TBP	1137	3931.0
TCEA1	4037	163.0
TCF12	1614	4852.0
TCF3	-2289	2738.0
TCF7	1204	-1623.0
TCF7L1	-3205	750.0
TCF7L2	-74	716.0
TDG	3925	3874.0
TDRKH	567	-1374.0
TEAD1	-4292	2647.0
TEAD2	323	-1534.0
TEAD3	-4846	-1975.0
TEAD4	-5380	-2538.0
TET1	3219	-3049.0
TET2	1688	1380.0
TET3	1591	923.0
TFAM	4351	-2053.0
TFB2M	4922	-3610.0
TFDP1	-2245	-3110.0
TFDP2	4029	-4963.0
TGFB1	-3111	4516.0
TGIF1	-2131	2058.0
THBS1	762	5034.0
THOC1	2868	2971.0
THOC2	4510	561.0
THOC3	2831	-3387.0
THOC5	4842	-589.0
THOC6	-904	2005.0
THOC7	-873	-3232.0
THRA	-5483	-5088.0
THRB	-1313	-2078.0
TJP1	405	-780.0
TMEM219	-3222	-1497.0
TMEM55B	3859	1390.0
TNFRSF10A	-3936	485.5
TNFRSF10B	-1612	485.5
TNFRSF10C	-2321	485.5
TNFRSF10D	-3227	485.5
TNKS1BP1	-4407	3365.0
TNRC6A	3585	2923.0
TNRC6B	3118	-2855.0
TNRC6C	-2020	1056.0
TOP3A	2607	3192.0
TOPBP1	2183	5010.0
TP53	575	3128.0
TP53BP2	4687	4246.0
TP53INP1	-2309	-1204.0
TP53RK	3992	-1473.0
TP63	3691	737.0
TPR	2984	275.0
TPX2	3446	2866.0
TRIAP1	901	-1776.0
TRIM28	4209	4779.0
TRIM33	2796	3628.0
TRIM63	-4866	-657.0
TSC1	2577	2054.0
TSC2	-4999	760.0
TSN	2947	-3359.0
TTC5	3302	1251.0
TTF1	4368	1895.0
TWIST1	2624	1741.0
TXN	1855	4827.0
TXNRD1	-2444	4222.0
U2AF2	4337	2964.0
UBC	2672	3877.0
UBE2C	4949	-3635.0
UBE2D1	-1588	-4657.0
UBE2D3	1424	5192.0
UBE2E1	-1132	-881.0
UBE2I	1246	733.0
UBE2S	4441	2868.0
UPF3B	1586	-4490.0
USP2	-5039	-3331.0
USP7	3857	2483.0
USP9X	1458	-295.0
UXT	-248	1389.0
VEGFA	-4571	-5070.0
VWA9	2598	187.0
WDR33	3143	-994.0
WDR5	-1608	-1067.0
WDR61	-1148	-234.0
WRN	98	2942.0
WWOX	1055	-3485.0
WWP1	-1200	-3658.0
WWTR1	-2503	3401.0
XPO5	2131	1149.0
YAF2	182	-3980.0
YAP1	-476	5038.0
YEATS4	3247	2348.0
YES1	-176	-836.0
YWHAB	3680	3468.0
YWHAE	1394	-2051.0
YWHAG	-2372	1012.0
YWHAH	-2777	3808.0
YWHAQ	963	3949.0
YWHAZ	2019	4919.0
ZC3H8	-3996	-4393.0
ZFHX3	-2823	417.0
ZFP1	777	319.0
ZFP14	-1564	-3984.0
ZFP2	-2603	-3410.0
ZFP28	4189	-3006.0
ZFP30	516	-4729.0
ZFP37	4076	4737.0
ZFP69	3315	-835.0
ZFP90	480	1589.0
ZFPM1	71	-424.0
ZIK1	4897	-2639.0
ZKSCAN1	-1405	3323.0
ZKSCAN3	630	-1709.5
ZKSCAN4	4031	-1709.5
ZKSCAN5	4612	4666.0
ZKSCAN7	-1769	-4305.0
ZKSCAN8	3190	-4662.0
ZNF101	4947	-4507.0
ZNF112	2487	-2356.0
ZNF12	2721	-1854.0
ZNF124	4126	-4507.0
ZNF143	1822	4676.0
ZNF169	-1838	2469.0
ZNF18	3432	731.0
ZNF180	3868	837.0
ZNF189	1916	-2878.0
ZNF202	2190	-29.0
ZNF205	-2430	-1059.0
ZNF212	554	209.0
ZNF213	-509	-2872.0
ZNF23	1671	-2324.0
ZNF235	2757	-5063.0
ZNF248	-2815	348.0
ZNF25	-3296	4949.0
ZNF250	-514	-2944.0
ZNF263	4581	565.0
ZNF274	4186	-3242.0
ZNF282	-3935	884.0
ZNF286A	3048	-3466.0
ZNF287	3780	248.0
ZNF3	3939	-3198.0
ZNF317	3402	2126.0
ZNF324	2644	870.5
ZNF324B	2800	870.5
ZNF334	961	4095.0
ZNF347	4334	-1317.5
ZNF354A	4577	-3937.0
ZNF354C	1442	-422.0
ZNF385A	-5211	2561.0
ZNF394	4721	-3911.0
ZNF398	1779	4090.0
ZNF416	4497	-1847.0
ZNF420	16	3556.0
ZNF426	3687	2349.0
ZNF429	-5017	-4551.5
ZNF43	4092	-4243.5
ZNF436	3688	-4649.0
ZNF445	-3447	-3700.0
ZNF446	-63	-3167.0
ZNF45	4715	-2195.0
ZNF454	921	1872.0
ZNF493	-3572	-4243.5
ZNF496	-2663	2740.0
ZNF521	629	2592.0
ZNF551	4427	-2653.0
ZNF559	4814	-3962.5
ZNF560	3600	71.0
ZNF561	-185	-2047.5
ZNF562	-55	-2047.5
ZNF566	549	2782.0
ZNF569	2722	-2125.0
ZNF585A	4317	-4688.0
ZNF597	3559	1798.0
ZNF606	1719	-4027.0
ZNF641	-4105	1543.0
ZNF655	1508	2730.0
ZNF660	-856	-3686.0
ZNF664	-1330	1319.0
ZNF665	359	-1317.5
ZNF667	1646	373.0
ZNF668	3548	1356.0
ZNF669	4901	-4507.0
ZNF678	3662	-3749.0
ZNF688	-1703	2294.0
ZNF689	2277	2174.0
ZNF691	1491	-4339.0
ZNF692	-475	-2200.0
ZNF697	-787	4142.0
ZNF703	-5506	-3976.0
ZNF704	-3376	1763.0
ZNF706	99	-3945.0
ZNF707	-1032	1219.0
ZNF710	-2142	-5087.0
ZNF720	4946	-5012.5
ZNF721	4971	-2996.5
ZNF738	4987	-5012.5
ZNF740	-4838	-3922.0
ZNF746	736	779.0
ZNF764	-1896	4603.0
ZNF770	4367	-3768.0
ZNF771	107	-2723.0
ZNF775	-3056	-3721.0
ZNF777	657	-960.0
ZNF790	-3148	-1937.0
ZNF791	4620	-4768.0
ZNF839	-808	-2227.0
ZSCAN25	2848	2086.0

---

---

Pyruvate metabolism and Citric Acid (TCA) cycle

Pyruvate metabolism and Citric Acid (TCA) cycle

metric	value
setSize	49
pMANOVA	4.72e-16
p.adjustMANOVA	2.91e-14
s.dist	0.727
s.human	-0.263
s.mouse	-0.678
p.human	0.00145
p.mouse	2.15e-16

Top 20 genes

Gene	human	mouse
IDH2	-5216	-4835
D2HGDH	-4890	-5104
PDK2	-5450	-4464
SDHA	-4773	-4748
OGDH	-5268	-4106
SLC16A3	-4751	-4193
MDH2	-4361	-4332
ACO2	-3822	-4534
MPC1	-3681	-4360
SDHC	-3712	-4323
IDH3G	-4178	-3714
NNT	-3325	-4200
VDAC1	-2909	-4782
ADHFE1	-4039	-3168
HAGH	-4509	-2740
IDH3B	-2881	-4194
PDHA1	-2405	-4692
GSTZ1	-2068	-5077
LDHA	-3251	-3213
IDH3A	-2155	-4265

Click HERE to show all gene set members

All member genes

	human	mouse
ACO2	-3822	-4534
ADHFE1	-4039	-3168
BSG	-2248	-3662
CS	3653	-4328
D2HGDH	-4890	-5104
DLAT	-1960	-4426
DLD	1187	-4834
DLST	-323	-4762
FAHD1	-1771	-4836
FH	287	-4146
GLO1	-678	-4289
GSTZ1	-2068	-5077
HAGH	-4509	-2740
IDH2	-5216	-4835
IDH3A	-2155	-4265
IDH3B	-2881	-4194
IDH3G	-4178	-3714
L2HGDH	-262	-2260
LDHA	-3251	-3213
LDHB	-1491	-4379
MDH2	-4361	-4332
ME1	1789	-534
ME2	-1789	3649
ME3	4207	-3631
MPC1	-3681	-4360
MPC2	829	-3712
NNT	-3325	-4200
OGDH	-5268	-4106
PDHA1	-2405	-4692
PDHB	-133	-4587
PDHX	-126	-4448
PDK1	4600	-3535
PDK2	-5450	-4464
PDK3	4747	5315
PDK4	-712	-4300
PDP1	-2175	-3641
PDP2	-2619	-3350
PDPR	-632	-3822
PPARD	-4213	2330
RXRA	-5519	1619
SDHA	-4773	-4748
SDHB	431	-4408
SDHC	-3712	-4323
SLC16A1	-987	2280
SLC16A3	-4751	-4193
SUCLA2	1517	-4804
SUCLG1	-31	-4434
SUCLG2	-1167	-4765
VDAC1	-2909	-4782

---

---

Immune System

Immune System

metric	value
setSize	1225
pMANOVA	2.42e-15
p.adjustMANOVA	1.42e-13
s.dist	0.137
s.human	-0.0241
s.mouse	0.135
p.human	0.169
p.mouse	1.21e-14

Top 20 genes

Gene	human	mouse
FBXO40	-5485	5326
SIRPA	-5627	4799
VCL	-4538	5383
FGF7	-5445	4475
SERPINB6	-5411	4298
ASB12	-4251	5435
PFKL	-4966	4614
MYO1C	-4842	4663
ANXA2	-4123	5407
EDA2R	-4901	4493
GDNF	-4043	5263
ALDH3B1	-4529	4664
TMBIM1	-4812	4333
CYB5R3	-5395	3844
CSF1	-4242	4888
STAT3	-3885	5276
LRRC41	-4474	4546
GALNS	-3960	5119
FBXL22	-4906	4122
DUSP2	-4253	4725

Click HERE to show all gene set members

All member genes

	human	mouse
AAAS	-3476.0	40.0
AAMP	2657.0	2106.0
ABCE1	4707.0	2085.0
ABHD17A	-1525.0	-2873.0
ABHD17B	1639.0	3541.0
ABHD17C	-2092.0	-100.0
ABI1	3792.0	3443.0
ABI2	-308.0	5438.0
ABL1	-4533.0	1377.0
ACLY	-2628.0	4526.0
ACTB	940.0	5427.0
ACTG1	-3075.0	5370.0
ACTN2	-3104.0	-1086.0
ACTR10	1853.0	920.0
ACTR1A	-4126.0	3959.0
ACTR1B	-4206.0	4382.0
ACTR2	3547.0	5008.0
ACTR3	1376.0	5496.0
ADAM10	-1509.0	1096.0
ADAM17	2407.0	736.0
ADAM8	-2592.0	4767.0
ADAR	-3014.0	581.0
AGA	1618.0	-5043.0
AGL	-4967.0	-4710.0
AGPAT2	-4979.0	-3846.0
AHCYL1	-3386.0	2570.0
AIP	-707.0	-2446.0
AKT1	-4954.0	1242.0
AKT2	-4057.0	-3488.0
AKT3	1343.0	2419.0
ALAD	-3855.0	-4632.0
ALDH3B1	-4529.0	4664.0
ALDOA	-5575.0	-3960.0
ALDOC	1379.0	4069.0
ALPK1	-1737.0	1616.0
AMPD3	-4286.0	4483.0
ANAPC1	572.0	-470.0
ANAPC10	1974.0	2927.0
ANAPC11	-3265.0	-2502.0
ANAPC13	-1663.0	-4282.0
ANAPC2	-2185.0	-1142.0
ANAPC4	-720.0	-3761.0
ANAPC5	1284.0	-3105.0
ANAPC7	1595.0	882.0
ANGPT1	-853.0	-3559.0
ANO6	-4134.0	4182.0
ANPEP	-215.0	-216.0
ANXA1	537.0	4783.0
ANXA2	-4123.0	5407.0
AP1B1	-4552.0	1126.0
AP1G1	4140.0	4718.0
AP1M1	3732.0	1165.0
AP1S1	-1410.0	80.0
AP1S2	-1634.0	3070.0
AP2A1	-3632.0	-3002.0
AP2A2	-1058.0	5459.0
AP2B1	-1157.0	4733.0
AP2M1	-2746.0	1678.0
AP2S1	1777.0	-582.0
APAF1	-3469.0	3979.0
APEH	-3390.0	-2532.0
APP	-2792.0	154.0
APRT	-3384.0	-223.0
ARAF	-3318.0	-4240.0
AREL1	4938.0	1211.0
ARF1	566.0	3011.0
ARHGAP9	-2941.0	-1677.0
ARIH1	4268.0	3623.0
ARIH2	-567.0	778.0
ARL2	-4142.0	-2108.0
ARL8A	-4586.0	3617.0
ARMC8	-194.0	-3654.0
ARPC1A	-120.0	2226.0
ARPC1B	669.0	4872.0
ARPC2	1357.0	2489.0
ARPC3	2873.0	1716.0
ARPC4	1698.0	-1177.0
ARPC5	2295.0	5164.0
ARRB1	-3133.0	2633.0
ARRB2	-1089.0	3740.0
ARSA	-3312.0	658.0
ARSB	-1001.0	3982.0
ART1	-5553.0	-4968.0
ASAH1	-3414.0	5351.0
ASB1	-3550.0	-421.0
ASB10	-4350.0	-4830.0
ASB11	-3603.0	901.0
ASB12	-4251.0	5435.0
ASB13	-4486.0	-4556.0
ASB14	-3742.0	-4935.0
ASB15	-3072.0	-4052.0
ASB16	-4432.0	-5065.0
ASB18	1023.0	-5051.0
ASB2	-4929.0	-3950.0
ASB4	-94.0	-3996.0
ASB5	-2529.0	4656.0
ASB6	1361.0	4072.0
ASB7	2584.0	1578.0
ASB8	2095.0	-4203.0
ATAD3B	1907.0	-4848.5
ATF1	3129.0	3005.0
ATF2	3130.0	2882.0
ATG12	4060.0	1099.0
ATG5	1661.0	660.0
ATG7	-1364.0	900.0
ATOX1	646.0	-270.0
ATP11A	-1843.0	619.0
ATP11B	4841.0	197.0
ATP6AP2	2114.0	5391.0
ATP6V0A1	-3809.0	3329.0
ATP6V0A2	186.0	-1285.0
ATP6V0B	-3461.0	-2887.0
ATP6V0D1	-2256.0	2038.0
ATP6V0E1	1861.0	1404.0
ATP6V0E2	-1727.0	-2450.0
ATP6V1A	1633.0	2509.0
ATP6V1B2	2299.0	4785.0
ATP6V1C1	3521.0	4933.0
ATP6V1D	3269.0	-4077.0
ATP6V1E1	3913.0	495.0
ATP6V1F	-3562.0	-1774.0
ATP6V1G2	1570.0	144.0
ATP6V1H	-57.0	1416.0
ATP7A	1448.0	2206.0
ATP8A1	1830.0	-2343.0
B2M	-731.0	-1801.0
B4GALT1	-1314.0	287.0
BAIAP2	-641.0	5424.0
BCL10	4124.0	3809.0
BCL2	-4633.0	-3007.0
BCL2L1	-5181.0	430.0
BCL6	-5018.0	1298.0
BIRC2	3739.0	-1431.0
BIRC3	-4741.0	1787.0
BLMH	-3217.0	332.0
BRAF	4103.0	3023.0
BRAP	4689.0	4314.0
BRI3	-3525.0	-3044.0
BRK1	2026.0	-636.0
BRWD1	2271.0	1847.0
BTBD1	-2710.0	-4812.0
BTBD6	-5281.0	-4050.0
BTRC	-1187.0	-2761.0
C1R	-813.0	-2544.0
C1S	-2427.0	-3402.0
C2	-558.0	-3222.0
C3	4311.0	-2705.0
C6orf120	1881.0	2505.0
C7	-1128.0	2548.0
CAB39	2485.0	4826.0
CALM1	-4464.0	1071.0
CALR	1534.0	4814.0
CAMK2A	-5527.0	-3819.0
CAMK2B	-5497.0	-2856.0
CAMK2D	-2223.0	5094.0
CAMK2G	-2097.0	-4184.0
CAND1	3370.0	5245.0
CANT1	511.0	2850.0
CANX	-836.0	4822.0
CAP1	2590.0	3803.0
CAPN1	-5166.0	-3782.0
CAPZA2	-1777.0	-1888.0
CAPZB	-3165.0	-2404.0
CASP1	-1298.0	1115.0
CASP2	2946.0	-2821.0
CASP3	423.0	5421.0
CASP8	-1646.0	3398.0
CASP9	-3269.0	-3219.0
CAT	-4828.0	-4447.0
CBL	1736.0	1563.0
CBLB	-3482.0	-468.0
CCL2	2620.0	5213.0
CCND1	757.0	1643.0
CCNF	3488.0	4322.0
CCT2	3805.0	5006.0
CCT8	4149.0	3936.0
CD274	3395.0	-2276.0
CD28	-2910.0	-4611.0
CD34	858.0	835.0
CD36	-582.0	-4709.0
CD44	837.0	5375.0
CD46	1543.0	-2023.0
CD47	-2184.0	997.0
CD55	220.0	-3197.0
CD59	1637.0	-3772.0
CD63	-3297.0	4795.0
CD81	-4675.0	59.0
CDC16	86.0	-1235.0
CDC23	3850.0	1048.0
CDC26	2750.0	2001.0
CDC27	665.0	3905.0
CDC34	-2923.0	-3453.0
CDC42	3308.0	965.0
CDK13	4123.0	3295.0
CDKN1A	-4927.0	3046.0
CEP290	3352.0	-1031.0
CFH	-556.0	277.0
CFL1	-909.0	5151.0
CHUK	216.0	3591.0
CKAP4	-3818.0	5046.0
CLCF1	-2419.0	3988.0
CLTA	1218.0	-119.0
CLTC	2268.0	2273.0
CLU	1629.0	2684.0
CMTM6	2331.0	4657.0
CNKSR1	-2870.0	3515.0
CNN2	-4870.0	2217.0
CNPY3	-3045.0	2799.0
COL1A2	-1712.0	1529.0
COLEC12	4261.0	1622.0
COMMD3	246.0	-4206.0
COMMD9	385.0	2670.0
COPB1	3916.0	5120.0
COTL1	-1553.0	5385.0
CPNE3	1228.0	-837.0
CPPED1	-3625.0	-4751.0
CRCP	1806.0	-1063.0
CREB1	2179.0	-1920.0
CREBBP	1506.0	4134.0
CREG1	1430.0	-1378.0
CRISPLD2	-871.0	-892.0
CRK	2145.0	4206.0
CRKL	-91.0	5262.0
CRLF1	42.0	531.0
CSF1	-4242.0	4888.0
CSK	-3610.0	4728.0
CSNK2B	1917.0	-1746.0
CSTB	-3426.0	4472.0
CTF1	-3242.0	-4939.0
CTNNB1	1714.0	2956.0
CTSA	-3537.0	-3391.0
CTSB	-1198.0	-1439.0
CTSC	2720.0	-35.0
CTSD	-4817.0	-2585.0
CTSF	-1942.0	-5092.0
CTSH	-3465.0	4096.0
CTSK	2.0	2230.0
CTSO	-774.0	-3618.0
CTSS	-339.0	3969.0
CTSV	2209.0	1721.0
CTSZ	-3890.0	3780.0
CUL1	-3121.0	-833.0
CUL2	4097.0	-3279.0
CUL3	2833.0	3311.0
CUL5	2599.0	-2062.0
CUL7	-4939.0	1928.0
CYB5R3	-5395.0	3844.0
CYBA	-633.0	2247.0
CYBB	-2550.0	3868.0
CYFIP2	-3775.0	-2981.0
CYLD	-1990.0	4116.0
CYSTM1	-1304.0	1546.0
DAB2IP	-5036.0	2828.0
DAPP1	4539.0	3373.0
DBNL	-2320.0	5161.0
DCTN1	-347.0	-4056.0
DCTN2	-3157.0	-3324.0
DCTN3	-943.0	1919.0
DCTN4	613.0	2402.0
DCTN5	2557.0	1890.0
DCTN6	1852.0	-3327.0
DDOST	320.0	4978.0
DDX3X	4686.0	5191.0
DDX41	273.0	372.0
DDX58	1593.0	809.0
DEGS1	-2228.0	4156.0
DERA	3823.0	2342.0
DET1	-2613.0	-1631.0
DGAT1	-2804.0	-766.0
DHX36	3822.0	-1009.0
DHX58	-2934.0	3216.0
DHX9	4151.0	2848.0
DIAPH1	3282.0	4405.0
DLG1	-52.0	2473.0
DLG3	-1567.0	-728.0
DLG4	-1594.0	1830.0
DNAJC13	1888.0	449.0
DNAJC3	1950.0	4619.0
DNAJC5	-2830.0	3712.0
DNASE1L1	-5205.0	-4988.0
DNM1	-747.0	1423.0
DNM2	-1149.0	218.0
DNM3	4865.0	1236.0
DOCK1	-226.0	2409.0
DOK3	-5498.0	1278.0
DPP7	-4199.0	3412.0
DSN1	2075.0	-665.0
DTX3L	-702.0	-3901.0
DTX4	4372.0	-1688.0
DUSP1	-219.0	1965.0
DUSP10	-5329.0	1869.0
DUSP16	3082.0	3867.0
DUSP2	-4253.0	4725.0
DUSP3	-5149.0	-4856.0
DUSP4	-3613.0	786.0
DUSP5	4084.0	5436.0
DUSP6	-528.0	-3212.0
DUSP7	-3477.0	-3896.0
DUSP8	1715.0	4441.0
DYNC1H1	-1442.0	1264.0
DYNC1I2	2591.0	172.0
DYNC1LI1	2883.0	981.0
DYNC1LI2	1750.0	3473.0
DYNLL1	-1331.0	3935.0
DYNLT1	2579.0	2427.0
DZIP3	336.0	2074.0
ECSIT	-2655.0	-4003.0
EDA	-124.0	4230.0
EDA2R	-4901.0	4493.0
EEA1	1370.0	3693.0
EEF1A1	-2150.0	3461.0
EEF2	-2853.0	740.0
EGF	-4568.0	-4926.0
EGFR	424.0	2978.0
EGR1	4164.0	4986.0
EIF2AK2	-486.0	-129.0
EIF4A1	2916.0	5463.0
EIF4A2	1360.0	849.0
EIF4A3	4491.0	2615.0
EIF4E	2892.0	2481.0
EIF4E2	-2440.0	724.0
EIF4E3	-2251.0	797.0
EIF4G1	-2988.0	-962.0
EIF4G2	1963.0	3349.0
EIF4G3	-2799.0	-188.0
ELK1	-3862.0	1269.0
ELMO1	-2166.0	2524.0
ELMO2	-354.0	1439.0
ENAH	4332.0	5533.0
ENPP4	-1280.0	-3522.0
EP300	3403.0	2309.0
ERAP1	-1974.0	-1614.0
ERBB2	-5511.0	494.0
ERBB3	-5290.0	-2307.0
ERP44	2150.0	1058.0
EVL	-3566.0	-1001.0
F13A1	-2059.0	4132.0
FABP5	-338.0	587.0
FADD	-571.0	3829.0
FAF2	3890.0	4157.0
FBXL12	4384.0	-3861.0
FBXL14	2633.0	2258.0
FBXL15	-1080.0	-560.0
FBXL16	-1561.0	3801.0
FBXL18	1610.0	-956.0
FBXL19	1130.0	2168.0
FBXL20	2822.0	-3659.0
FBXL22	-4906.0	4122.0
FBXL3	3227.0	3766.0
FBXL4	2514.0	-3677.0
FBXL5	2542.0	2526.0
FBXL8	-1774.0	2949.0
FBXO10	-5271.0	868.0
FBXO11	-962.0	1111.0
FBXO17	-3932.0	3092.0
FBXO21	-481.0	-4704.0
FBXO22	-1604.0	-2014.0
FBXO30	2102.0	3555.0
FBXO31	-4655.0	-4480.0
FBXO32	-4380.0	-4503.0
FBXO4	-1189.0	3319.0
FBXO40	-5485.0	5326.0
FBXO44	-2981.0	-4529.0
FBXO6	3598.0	-4955.0
FBXO7	375.0	-1818.0
FBXO9	-1473.0	-1346.0
FBXW11	4385.0	5178.0
FBXW2	-2282.0	-1043.0
FBXW4	-4330.0	-2623.0
FBXW5	-4784.0	-3551.0
FBXW7	-886.0	1644.0
FBXW8	-2816.0	2245.0
FBXW9	-1076.0	1.0
FGF1	798.0	5410.0
FGF2	751.0	3502.0
FGF7	-5445.0	4475.0
FGF9	-5320.0	-1375.0
FGFR1	-1499.0	-1279.0
FGFR3	3759.0	4811.0
FGFR4	-5312.0	-991.0
FGL2	-1862.0	3337.0
FLNA	-3248.0	4449.0
FLNB	2772.0	2143.0
FN1	35.0	4381.0
FNTA	1578.0	-3409.0
FNTB	-690.0	3507.0
FOS	1865.0	5350.0
FOXO1	-432.0	3792.0
FOXO3	-42.0	2244.0
FRK	194.0	2355.0
FRS2	4678.0	3571.0
FRS3	1398.0	1630.0
FSCN1	1705.0	-2925.0
FTH1	-1890.0	-2807.0
FUCA1	111.0	1204.0
FUCA2	-2160.0	-2430.0
FYB	-2235.0	-89.0
FYN	-2850.0	4537.0
FZR1	-1244.0	3161.0
GAA	-5001.0	-2492.0
GAB1	-1853.0	-1642.0
GAB2	4053.0	2415.0
GALNS	-3960.0	5119.0
GBP6	-2110.0	-3690.0
GCA	2461.0	-3509.0
GDI2	865.0	4995.0
GDNF	-4043.0	5263.0
GFRA1	-4438.0	-426.0
GGH	3482.0	592.0
GHDC	-3542.0	-2146.0
GHR	3997.0	-4315.0
GLA	3418.0	-1236.0
GLB1	-2244.0	2071.0
GLMN	4722.0	1505.0
GM2A	-1169.0	1984.0
GNS	101.0	639.0
GOLGA7	1185.0	2154.0
GPI	-5210.0	-4750.0
GRB2	-4050.0	3027.0
GRN	-4029.0	2510.0
GSDMD	-2517.0	588.0
GSN	72.0	-78.0
GSTO1	-2055.0	-3769.0
GUSB	1923.0	4620.0
GYG1	-3875.0	4407.0
HACE1	374.0	-574.0
HBEGF	3484.0	5518.0
HECTD1	1958.0	-4124.0
HECTD2	-3544.0	2745.0
HECTD3	-519.0	-3622.0
HECW2	-1074.0	490.0
HERC1	-3474.0	-2434.0
HERC3	1164.0	3660.0
HERC4	1215.0	5231.0
HERC6	168.0	-775.0
HEXB	753.0	1511.0
HGSNAT	-4600.0	349.0
HIF1A	-1016.0	5349.0
HLA-DMA	1128.0	1486.0
HMGB1	-2199.0	-3939.0
HMOX1	-2843.0	4573.0
HMOX2	-687.0	-3441.0
HNRNPA2B1	3693.0	-4286.0
HNRNPF	4978.0	3406.0
HRAS	-4545.0	-4872.0
HSP90AA1	3656.0	5525.0
HSP90AB1	-639.0	5203.0
HSP90B1	460.0	4768.0
HSPA1A	4887.0	5534.5
HSPA1B	4676.0	5534.5
HSPA5	2574.0	5400.0
HSPA8	3674.0	5419.0
HSPA9	2342.0	-3484.0
HUWE1	-673.0	397.0
HVCN1	-2318.0	-3745.0
ICAM1	1056.0	41.0
ICAM2	-1505.0	-2453.0
ICMT	-2315.0	2796.0
IDH1	1160.0	-4779.0
IFI16	-1127.0	5085.5
IFI27	-1101.0	-134.0
IFI35	-3310.0	-509.0
IFIH1	-204.0	-2805.0
IFIT2	-1338.0	640.0
IFIT3	-792.0	-918.0
IFITM1	1574.0	4937.0
IFITM2	-316.0	4937.0
IFITM3	380.0	4937.0
IFNAR1	3645.0	1778.0
IFNAR2	-1316.0	1704.0
IFNGR1	2506.0	1520.0
IFNGR2	-386.0	-3292.0
IGF2R	-2030.0	2034.0
IKBKB	-4093.0	2980.0
IL10RB	1239.0	2957.0
IL11RA	-5610.0	-2130.0
IL13RA1	-1847.0	4373.0
IL15	-2409.0	-4017.0
IL16	-1613.0	-1580.0
IL17RA	219.0	5136.0
IL17RC	-4271.0	962.0
IL17RD	-3179.0	1019.0
IL17RE	-1865.0	-3165.0
IL18BP	292.0	-52.0
IL1R1	-3018.0	4729.0
IL1RAP	627.0	4100.0
IL20RB	-159.0	844.0
IL2RG	-1943.0	582.0
IL33	1864.0	3634.0
IL34	3060.0	-245.0
IL4R	-3335.0	5166.0
IL6R	-5515.0	2529.0
IL6ST	3055.0	1967.0
ILF2	4835.0	3568.0
IMPDH1	-827.0	3626.0
IMPDH2	822.0	-801.0
INPP5D	-2433.0	4627.0
INPPL1	-5220.0	-2663.0
IP6K2	3404.0	-226.0
IQGAP1	-415.0	4295.0
IRAK1	-4351.0	-1420.0
IRAK2	-4255.0	3504.0
IRAK3	95.0	1205.0
IRAK4	-569.0	3445.0
IRF1	-1565.0	-1908.0
IRF2	-3387.0	-1585.0
IRF3	-3061.0	-2463.0
IRF4	-1166.0	4447.0
IRF7	775.0	2624.0
IRF9	1267.0	-1738.0
IRS1	-5550.0	-3910.0
IRS2	3384.0	2249.0
ISG15	-3928.0	-331.0
IST1	3827.0	3890.0
ITCH	4319.0	2263.0
ITGA4	-2878.0	-2673.0
ITGAM	-2633.0	5000.0
ITGAV	-819.0	2947.0
ITGAX	-896.0	-49.0
ITGB1	956.0	5174.0
ITGB2	-107.0	4082.0
ITGB3	-488.0	5180.0
ITGB5	-2578.0	-4752.0
ITPR1	4903.0	1106.0
ITPR2	1242.0	53.0
ITPR3	-3631.0	-2403.0
JAK1	-1869.0	4962.0
JAK2	-2569.0	-2171.0
JUN	2469.0	5472.0
JUNB	-2593.0	4931.0
JUP	1723.0	4991.0
KBTBD7	1566.0	3776.0
KBTBD8	4994.0	3968.0
KCMF1	501.0	-106.0
KCNAB2	-3198.0	3369.0
KCTD6	2748.0	2384.0
KCTD7	-1996.0	-1508.5
KEAP1	-1297.0	-2799.0
KIF11	2319.0	3552.0
KIF18A	3832.0	2448.0
KIF23	1216.0	2656.0
KIF2A	-4390.0	4073.0
KIF3A	4718.0	3190.0
KIF3B	3571.0	3912.0
KIF3C	-3766.0	-1414.0
KIF5A	4430.0	584.0
KIF5B	838.0	4559.0
KIF5C	4658.0	2757.0
KIFAP3	-1339.0	-4044.0
KITLG	4898.0	-361.0
KLC1	-3922.0	2207.0
KLC2	-1732.0	-487.0
KLC4	-3559.0	-2759.0
KLHL11	788.0	1751.0
KLHL13	-4145.0	618.0
KLHL2	624.0	2364.0
KLHL20	3341.0	-3717.0
KLHL21	-3865.0	-4851.0
KLHL22	-4107.0	-1183.0
KLHL25	-2113.0	2044.0
KLHL3	-3824.0	-3370.0
KLHL41	-2822.0	5529.0
KLHL42	-441.0	917.0
KLHL5	4206.0	4235.0
KLHL9	4740.0	359.0
KPNA1	1833.0	4786.0
KPNA2	5007.0	4653.0
KPNA3	-2337.0	-979.0
KPNA4	1501.0	5379.0
KPNB1	3619.0	4744.0
KRAS	3546.0	5146.0
KSR1	-5578.0	-1928.0
LAMA5	-5584.0	-201.0
LAMP1	764.0	-3620.0
LAMP2	-2579.0	4194.0
LAMTOR1	-800.0	-4509.0
LAMTOR2	-1715.0	-4532.0
LAMTOR3	3134.0	781.0
LAT2	-1020.0	1710.0
LGALS3	1062.0	4689.0
LGMN	4834.0	651.0
LIFR	-994.0	-4778.0
LIMK1	-4857.0	3467.0
LMNB1	3392.0	648.0
LMO7	-3084.0	-3361.0
LNPEP	463.0	826.0
LNX1	-4202.0	1744.0
LONRF1	672.0	-588.0
LPCAT1	-1659.0	2360.0
LRRC41	-4474.0	4546.0
LRRFIP1	-4175.0	-3317.0
LRSAM1	-4650.0	-2475.0
LTA4H	1584.0	2751.0
LTBR	-4989.0	707.0
LTN1	4960.0	-1005.0
LYN	785.0	2842.0
LYPLA1	1177.0	-3204.0
MAGT1	1192.0	-616.0
MALT1	-2616.0	-3716.0
MAN2B1	-3000.0	564.0
MANBA	-1928.0	-2624.0
MAOA	-96.0	3828.0
MAP2K1	-506.0	-3734.0
MAP2K2	-3813.0	-2235.0
MAP2K3	-4716.0	3926.0
MAP2K4	8.0	1873.0
MAP2K6	1456.0	-4331.0
MAP2K7	794.0	-4191.0
MAP3K1	1124.0	-642.0
MAP3K11	-3624.0	2252.0
MAP3K3	2825.0	2589.0
MAP3K7	2142.0	1585.0
MAP3K8	344.0	1263.0
MAPK1	1988.0	-969.0
MAPK10	-3504.0	-1276.0
MAPK11	-3385.0	1370.0
MAPK12	-5264.0	99.0
MAPK14	-1562.0	-2824.0
MAPK3	-1024.0	4464.0
MAPK7	-729.0	2102.0
MAPK8	457.0	1743.0
MAPK9	-3854.0	-738.0
MAPKAP1	-405.0	1545.0
MAPKAPK2	-2489.0	-1825.0
MAPKAPK3	-4795.0	1592.0
MARK3	3178.0	989.0
MASP1	-4224.0	298.0
MAVS	-4768.0	-4641.0
MCL1	2837.0	5057.0
MEF2A	-5175.0	-1587.0
MEF2C	-4610.0	2307.0
MET	-3529.0	4440.0
METTL7A	-5605.0	-4947.0
MEX3C	4035.0	5376.0
MGRN1	-3720.0	-2536.0
MGST1	427.0	-2928.0
MIB2	-4266.0	194.0
MID1	-4726.0	-13.0
MIF	-2307.0	-3224.0
MKRN1	2493.0	-2142.0
MLEC	-3173.0	317.0
MLST8	-3485.0	-1820.0
MME	-3346.0	-1455.0
MMP2	-692.0	-606.0
MOSPD2	3720.0	-1551.0
MRAS	-5239.0	525.0
MRC2	-970.0	3073.0
MSN	-3907.0	4981.0
MTAP	-2515.0	2769.0
MTOR	-1191.0	583.0
MVP	-4506.0	1795.0
MX1	-1867.0	3839.0
MYC	3994.0	185.0
MYD88	2726.0	2870.0
MYH2	-3080.0	-1826.0
MYH9	-1879.0	4997.0
MYLIP	-4026.0	-3523.0
MYO10	1381.0	2797.0
MYO1C	-4842.0	4663.0
MYO5A	-885.0	4252.0
MYO9B	-1901.0	4621.0
NBEAL2	-4727.0	1478.0
NCAM1	-3954.0	4316.0
NCK1	3718.0	2059.0
NCKAP1	3563.0	5090.0
NCKIPSD	-2821.0	3136.0
NCSTN	-2504.0	-846.0
NDC1	1273.0	-322.0
NDN	1146.0	1941.0
NDUFC2	34.0	-4249.0
NEDD4	4583.0	-2859.0
NEDD4L	4279.0	95.0
NEU1	1863.0	2997.0
NF1	3095.0	3040.0
NF2	-1449.0	-3031.0
NFASC	-2394.0	3767.0
NFATC1	-5337.0	-3274.0
NFATC2	-3264.0	2685.0
NFATC3	-3321.0	1846.0
NFKB1	-4233.0	2228.0
NFKB2	-3926.0	2289.0
NFKBIA	-4263.0	1229.0
NFKBIB	4450.0	2806.0
NFKBIE	-4165.0	-1357.0
NHLRC3	-3747.0	3010.0
NIT2	-1606.0	-413.0
NKIRAS1	4369.0	-4175.0
NKIRAS2	-1369.0	665.0
NLRC3	-2924.0	-1284.0
NLRC5	-4398.0	-1577.0
NLRX1	-4825.0	-3704.0
NOD1	-3886.0	-667.0
NOD2	-4402.0	2741.0
NOS1	-4260.0	-3419.0
NPC2	790.0	1192.0
NPDC1	-2124.0	2748.0
NPEPPS	44.0	-2846.0
NRAS	4354.0	1003.0
NUP107	3232.0	3195.0
NUP133	889.0	-2580.0
NUP153	4762.0	4031.0
NUP155	4306.0	2897.0
NUP160	3998.0	2314.0
NUP188	2117.0	4593.0
NUP205	4438.0	3917.0
NUP214	3124.0	1845.0
NUP35	4571.0	2515.0
NUP37	-327.0	-873.0
NUP43	4562.0	193.0
NUP54	4508.0	4751.0
NUP85	3181.0	227.0
NUP88	1244.0	1407.0
NUP93	-1503.0	5229.0
NUP98	4235.0	5486.0
OAS2	212.0	2134.0
ORAI2	936.0	56.0
ORMDL3	893.0	3754.0
OSBPL1A	-2961.0	-5076.0
OSMR	255.0	5081.0
OSTF1	2228.0	-712.0
OTUD5	4179.0	2056.0
P4HB	-2525.0	5054.0
PADI2	-5625.0	-4412.0
PAFAH1B2	3709.0	5290.0
PAG1	-2006.0	3400.0
PAK1	-5419.0	-4706.0
PAK2	1525.0	5331.0
PANX1	1142.0	3665.0
PAQR3	396.0	3145.0
PARK2	-4936.0	-2564.0
PDAP1	-1236.0	-1152.0
PDCD4	2217.0	1970.0
PDE12	4844.0	4427.0
PDE6D	-2753.0	649.0
PDGFA	-4328.0	-2495.0
PDGFB	-606.0	1041.0
PDGFRA	2727.0	1223.0
PDGFRB	-2260.0	2970.0
PDIA3	3090.0	5440.0
PDPK1	3443.0	3947.0
PDXK	-4690.0	-936.0
PDZD11	1678.0	-2562.0
PEA15	-1982.0	1535.0
PEBP1	-3678.0	-3474.0
PELI1	4489.0	5252.0
PELI2	3371.0	1384.0
PELI3	-4396.0	2800.0
PFKL	-4966.0	4614.0
PGM1	-4270.0	-4828.0
PGM2	-561.0	4131.0
PGRMC1	-333.0	-191.0
PHB	-586.0	-3838.0
PIAS1	57.0	627.0
PIK3AP1	966.0	3017.0
PIK3C3	3439.0	-1596.0
PIK3CA	365.0	4218.0
PIK3CB	2760.0	5125.0
PIK3CD	-4322.0	-2306.0
PIK3R1	2896.0	-813.0
PIK3R3	3188.0	3545.0
PIK3R4	3839.0	-3124.0
PIM1	-228.0	1633.0
PIN1	-3515.0	-3234.0
PITPNA	-2450.0	-1450.0
PJA1	1991.0	-985.0
PJA2	397.0	304.0
PKM	-4231.0	-3432.0
PLA2G6	-3913.0	-2025.0
PLAU	-548.0	595.0
PLAUR	-638.0	2110.0
PLCG1	-3955.0	-1787.0
PLD1	55.0	46.0
PLD2	-60.0	-498.0
PLD3	-5217.0	18.0
PLEKHO2	-717.0	3001.0
PML	3338.0	3242.0
PNP	5019.5	4921.0
POLR1C	3643.0	3611.0
POLR1D	413.0	-1581.0
POLR2E	-667.0	148.0
POLR2H	-3927.0	2213.0
POLR2K	2480.0	-3599.0
POLR2L	-4314.0	-1126.0
POLR3A	4348.0	-1472.0
POLR3B	2547.0	-2035.0
POLR3C	4052.0	859.0
POLR3D	381.0	-435.0
POLR3E	1908.0	1839.0
POLR3F	4054.0	5048.0
POLR3G	1455.0	3939.0
POLR3GL	-1424.0	-4510.0
POLR3H	282.0	294.0
POLR3K	4716.0	-3380.0
POU2F1	3019.0	-1366.0
PPIA	-4031.0	4207.0
PPIE	2144.0	-1849.0
PPL	-2270.0	-1324.0
PPM1B	4912.0	2379.0
PPP1CB	-1374.0	-3335.0
PPP1CC	4081.0	-1627.0
PPP2CA	4482.0	1672.0
PPP2CB	2458.0	2352.0
PPP2R1A	-4013.0	-681.0
PPP2R1B	3028.0	3194.0
PPP2R5A	4590.0	3889.0
PPP2R5B	-1524.0	-765.0
PPP2R5C	-2508.0	-293.0
PPP2R5D	-3449.0	-620.0
PPP2R5E	4644.0	2107.0
PPP3CA	109.0	-1172.0
PPP3CB	-3435.0	-1839.0
PPP5C	-4582.0	-3591.0
PRCP	970.0	598.0
PRDX4	132.0	857.0
PRDX6	-3481.0	4983.0
PRKACA	-4691.0	-4303.0
PRKACB	-2659.0	-360.0
PRKCD	-4276.0	1141.0
PRKCE	-4307.0	-348.0
PRKCQ	-5095.0	-4724.0
PRKCSH	-268.0	367.0
PRKDC	2294.0	3813.0
PRKG1	1401.0	5353.0
PROS1	103.0	2992.0
PRR5	-837.0	161.0
PSAP	-2247.0	-4177.0
PSEN1	2070.0	3570.0
PSMA1	2820.0	4043.0
PSMA3	3434.0	-1035.0
PSMA4	769.0	-1962.0
PSMA6	2199.0	-1657.0
PSMA7	-2980.0	-1038.0
PSMB1	954.0	-1037.0
PSMB10	-1800.0	-831.0
PSMB2	618.0	-67.0
PSMB4	-235.0	-559.0
PSMB5	-4113.0	-2597.0
PSMB6	-793.0	-1795.0
PSMB7	-831.0	-2699.0
PSMB8	-675.0	-2510.0
PSMB9	-1611.0	-3558.0
PSMC1	449.0	1146.0
PSMC2	-1311.0	3386.0
PSMC3	-2439.0	-1846.0
PSMC4	2724.0	-205.0
PSMC5	1212.0	-1680.0
PSMC6	-2520.0	3114.0
PSMD1	2619.0	3210.0
PSMD10	-1227.0	361.0
PSMD11	995.0	5504.0
PSMD12	3831.0	-462.0
PSMD13	821.0	532.0
PSMD14	-635.0	3746.0
PSMD2	-713.0	741.0
PSMD3	-3343.0	-354.0
PSMD4	-214.0	968.0
PSMD5	1807.0	4479.0
PSMD6	3537.0	-3784.0
PSMD7	-2329.0	410.0
PSMD8	-3171.0	4292.0
PSMD9	4204.0	-3586.0
PSME1	-2771.0	-2861.0
PSME2	-4085.0	-41.0
PSME3	3333.0	491.0
PSME4	1960.0	2319.0
PSMF1	683.0	-1768.0
PTEN	2797.0	4830.0
PTGES2	-2699.0	-3773.0
PTK2	-2497.0	2145.0
PTK2B	-2461.0	2430.0
PTPN1	1531.0	4935.0
PTPN11	-1575.0	3105.0
PTPN12	4141.0	5222.0
PTPN13	4200.0	1720.0
PTPN14	1287.0	-1576.0
PTPN18	-4024.0	2162.0
PTPN2	4314.0	5012.0
PTPN22	400.0	391.0
PTPN23	1152.0	5190.0
PTPN3	2224.0	-5017.0
PTPN4	-1408.0	5055.0
PTPN6	-931.0	4180.0
PTPN9	-1215.0	3574.0
PTPRA	-402.0	3484.0
PTPRB	-4654.0	-1500.0
PTPRJ	391.0	4189.0
PTX3	-1790.0	-2063.0
PYCARD	-2810.0	3218.0
PYGB	-4498.0	2607.0
PYGL	-3546.0	2519.0
QPCT	250.0	4753.0
QSOX1	2045.0	3683.0
RAB10	-2646.0	-3833.0
RAB14	2341.0	-431.0
RAB18	4588.0	-2104.0
RAB24	-1792.0	-4802.0
RAB27A	169.0	-190.0
RAB31	-547.0	4317.0
RAB3A	75.0	-4870.0
RAB3D	3527.0	2881.0
RAB5B	584.0	-3999.0
RAB5C	2317.0	3682.0
RAB7A	-383.0	3232.0
RAC1	2525.0	-240.0
RAC2	41.0	4138.0
RACGAP1	4239.0	3807.0
RAE1	4471.0	3078.0
RAF1	1712.0	-1201.0
RALA	-1368.0	-1154.0
RALGDS	-5190.0	2802.0
RANBP2	4470.0	-562.0
RANBP9	4005.0	2691.0
RAP1A	-689.0	3944.0
RAP1B	4479.0	5079.0
RAP1GAP	-894.0	-1740.0
RAP1GAP2	-1674.0	3501.0
RAP2B	3971.0	4719.0
RAP2C	-983.0	-776.0
RAPGEF1	-3992.0	4925.0
RAPGEF2	4504.0	-1660.0
RAPGEF3	108.0	-2916.0
RAPGEF4	4622.0	4334.0
RASA1	-612.0	2537.0
RASA2	3565.0	2417.0
RASA3	-4990.0	-58.0
RASAL2	3510.0	686.0
RASGRF2	4373.0	-3126.0
RASGRP2	-2556.0	-4004.0
RASGRP3	-4774.0	-4929.0
RBBP6	5003.0	344.0
RBCK1	-4445.0	-2999.0
RBX1	-733.0	-2400.0
RCE1	2361.0	2291.0
RCHY1	4693.0	1089.0
REL	1608.0	5431.0
RELA	1783.0	4454.0
RELB	-2305.0	2910.0
RGL1	-161.0	-624.0
RGL2	-4344.0	-4226.0
RHOA	539.0	4106.0
RHOG	-1207.0	5167.0
RHOU	-4229.0	-3685.0
RICTOR	3562.0	1082.0
RILP	-4284.0	-4896.0
RIPK1	325.0	189.0
RIPK2	3609.0	4684.0
RLIM	4910.0	2000.0
RNASEL	2906.0	-20.0
RNASET2	-4153.0	-4148.0
RNF111	3964.0	5247.0
RNF114	722.0	-3747.0
RNF123	-5370.0	-4694.0
RNF125	3620.0	-570.0
RNF126	1365.0	-339.0
RNF130	-3856.0	-2278.0
RNF135	-3677.0	1588.0
RNF138	3588.0	4258.0
RNF14	-3571.0	1064.0
RNF144B	1106.0	-1871.0
RNF19A	-1550.0	4590.0
RNF19B	1703.0	5482.0
RNF213	-4087.0	497.0
RNF216	-4323.0	2967.0
RNF217	-5062.0	-692.0
RNF220	-1966.0	2982.0
RNF25	3292.0	3258.0
RNF34	3719.0	-1003.0
RNF4	4630.0	5219.0
RNF41	1588.0	4825.0
RNF6	4859.0	-2036.0
RNF7	-3180.0	-4011.0
ROCK1	4876.0	3865.0
RORA	-5056.0	2669.0
RORC	-5248.0	-3275.0
RPS27A	783.0	-2165.0
RPS6KA1	-1481.0	-1813.0
RPS6KA2	-4748.0	-4135.0
RPS6KA3	952.0	2296.0
RPS6KA5	51.0	-4805.0
S100A1	-4789.0	-4016.0
S100A11	-3518.0	4873.0
S1PR1	2689.0	-1019.0
SAMHD1	48.0	-2043.0
SAR1B	2914.0	-3753.0
SCAMP1	-549.0	1425.0
SDC1	-2046.0	1023.0
SDCBP	4377.0	4250.0
SEC13	730.0	938.0
SEC23A	3177.0	-2521.0
SEC24A	4282.0	-949.0
SEC24B	3112.0	4347.0
SEC24C	2739.0	1142.0
SEC24D	265.0	4769.0
SEC31A	3713.0	1713.0
SEC61A1	1613.0	5134.0
SEC61A2	4702.0	-3506.0
SEC61G	2374.0	-461.0
SEH1L	1085.0	4110.0
SERPINB1	1882.0	5473.0
SERPINB6	-5411.0	4298.0
SERPING1	78.0	-151.0
SH2B1	-3841.0	1127.0
SH3KBP1	1014.0	-4274.0
SH3RF1	2014.0	-977.0
SHC1	3976.0	4815.0
SHC2	-3710.0	3451.0
SHOC2	4514.0	3567.0
SIAH1	5006.0	1241.0
SIAH2	-1998.0	5492.0
SIGIRR	-452.0	-2169.0
SIKE1	-73.0	3034.0
SIPA1	-3247.0	-965.0
SIRPA	-5627.0	4799.0
SKP1	2028.0	-1286.0
SKP2	4205.0	4241.0
SLC15A4	-527.0	308.0
SLC2A3	5004.0	2223.5
SLC44A2	-5438.0	-4047.0
SMAD3	-3794.0	-3710.0
SMARCA4	-3874.0	863.0
SMURF1	4443.0	-1337.0
SMURF2	1070.0	5348.0
SNAP23	372.0	2500.0
SNAP29	-2698.0	2654.0
SNRPA1	4117.0	3762.0
SOCS1	199.0	3983.0
SOCS3	-283.0	4943.0
SOCS5	4145.0	2774.0
SOD1	157.0	-2728.0
SOD2	-1568.0	-4837.0
SOS1	-1962.0	2326.0
SOS2	-563.0	-2646.0
SPRED1	3312.0	4628.0
SPRED2	1200.0	-1956.0
SPRED3	-2447.0	-207.0
SPSB1	-2984.0	952.0
SPSB2	530.0	3981.0
SPTAN1	-2425.0	412.0
SPTB	-5499.0	1118.0
SPTBN1	-2919.0	-1221.0
SQSTM1	-3803.0	4448.0
SRC	-3910.0	3763.0
SRP14	2888.0	-3550.0
STAT1	236.0	-3457.0
STAT2	-2601.0	-1249.0
STAT3	-3885.0	5276.0
STAT5A	-4125.0	-4449.0
STAT5B	-5022.0	-3552.0
STAT6	-5317.0	-88.0
STIM1	-3417.0	-3701.0
STK10	-3246.0	1876.0
STK11IP	-451.0	-2225.0
STOM	2424.0	4910.0
STUB1	-2898.0	-3668.0
STX1A	-411.0	1598.0
STX3	4376.0	419.0
STX4	-2347.0	-2961.0
SUGT1	3140.0	-4993.0
SUMO1	4213.0	-262.0
SURF4	1238.0	4861.0
SVIP	3363.0	-4374.0
SYNGAP1	-3658.0	2878.0
SYNGR1	-4900.0	-4120.0
TAB1	-4874.0	-4377.0
TAB2	2791.0	3798.0
TAB3	2116.0	5258.0
TALDO1	-2080.0	-2543.0
TANK	3655.0	3759.0
TAP1	-4923.0	-1630.0
TAP2	-1124.0	-2076.0
TAPBP	-3007.0	-437.0
TAX1BP1	3222.0	-87.0
TBK1	673.0	2827.0
TCIRG1	-3600.0	4574.0
TCP1	4480.0	394.0
TEC	3728.0	3350.0
TEK	3580.0	-1484.0
TGFB1	-3111.0	4516.0
THEM4	-3616.0	-2987.0
THOP1	-3684.0	-4531.0
TICAM1	1624.0	1665.0
TIFA	-1142.0	-448.0
TIMP1	-1317.0	5467.0
TIMP2	-1886.0	1226.0
TIRAP	-2943.0	242.0
TLN1	-3918.0	3071.0
TLR3	-310.0	-1745.0
TLR4	1065.0	4797.0
TLR5	-3234.0	-1217.0
TLR6	888.0	2027.0
TMBIM1	-4812.0	4333.0
TMC6	-4677.0	1043.0
TMEM30A	2855.0	-2091.0
TMEM63A	-4829.0	3044.0
TNFAIP3	-5203.0	3469.0
TNFAIP6	1870.0	4169.0
TNFRSF12A	1487.0	5373.0
TNFRSF14	-3195.0	155.0
TNFRSF1A	-4666.0	3341.0
TNFRSF1B	-874.0	4531.0
TNFRSF25	-3839.0	-1985.0
TNFSF12	-5179.0	-4391.0
TNIP2	-1370.0	4330.0
TOLLIP	-256.0	1819.0
TOM1	-5386.0	-2820.0
TP53	575.0	3128.0
TPP2	-1775.0	4120.0
TPR	2984.0	275.0
TRAF2	-1546.0	2643.0
TRAF3	-3815.0	4367.0
TRAF6	3468.0	4662.0
TRAF7	-4038.0	3963.0
TRAIP	389.0	1449.0
TRAPPC1	368.0	-3150.0
TRIB3	-1004.0	2359.0
TRIM11	2388.0	1291.0
TRIM2	28.0	2380.0
TRIM21	2960.0	-2527.0
TRIM25	-3243.0	-1502.0
TRIM26	2745.0	2403.0
TRIM3	-1373.0	4302.0
TRIM32	1027.0	5067.0
TRIM35	3906.0	-2316.0
TRIM36	4848.0	3432.0
TRIM37	3675.0	2053.0
TRIM39	2189.0	-1365.0
TRIM41	3064.0	3169.0
TRIM45	-2733.0	4675.0
TRIM5	1812.0	-4962.0
TRIM56	-3368.0	-2264.0
TRIM62	-4984.0	1637.0
TRIM63	-4866.0	-657.0
TRIM68	3519.0	-5044.0
TRIM8	-5354.0	1324.0
TRIP12	3234.0	-1045.0
TRPC1	1744.0	1215.0
TSPAN14	-4941.0	-2779.0
TUBB	-3118.0	5321.0
TUBB4B	430.0	4642.0
TWIST1	2624.0	1741.0
TXLNA	-3216.0	3117.0
TXN	1855.0	4827.0
TYK2	-3123.0	725.0
UBA1	-3060.0	3496.0
UBA3	3512.0	3512.0
UBA5	1035.0	4836.0
UBA6	3538.0	3274.0
UBA7	-1671.0	-2885.0
UBAC1	-5381.0	-3797.0
UBC	2672.0	3877.0
UBE2A	-4243.0	761.0
UBE2B	1060.0	-4121.0
UBE2C	4949.0	-3635.0
UBE2D1	-1588.0	-4657.0
UBE2D2	-1986.0	1804.0
UBE2D3	1424.0	5192.0
UBE2E1	-1132.0	-881.0
UBE2E2	-2834.0	4163.0
UBE2E3	-4054.0	-2239.0
UBE2F	-2462.0	-486.0
UBE2G1	-2888.0	-4644.0
UBE2G2	-2535.0	-1781.0
UBE2H	2136.0	-2845.0
UBE2J1	-478.0	5011.0
UBE2J2	383.0	-532.0
UBE2K	1393.0	1348.0
UBE2L3	3051.0	-2249.0
UBE2L6	-3548.0	3305.0
UBE2M	1247.0	-854.0
UBE2N	2545.0	4245.0
UBE2O	-1419.0	4017.0
UBE2Q1	-926.0	3621.0
UBE2R2	-2829.0	-3280.0
UBE2S	4441.0	2868.0
UBE2V2	-334.0	2814.0
UBE2Z	2065.0	5107.0
UBE3A	2353.0	-967.0
UBE3B	-4415.0	-1310.0
UBE3C	881.0	72.0
UBE3D	3787.0	-690.0
UBE4A	3862.0	1701.0
UBOX5	-4280.0	-901.0
UBR1	1605.0	-1002.0
UBR2	-1673.0	-4136.0
UBR4	2440.0	758.0
UFL1	2738.0	4702.0
UNKL	442.0	1913.0
USP18	45.0	-3032.0
VAMP2	-3293.0	-1899.0
VAMP3	1372.0	695.0
VAMP7	2376.0	846.0
VAMP8	-2728.0	-4982.0
VAPA	2838.0	2825.0
VASP	-142.0	2533.0
VAT1	-4095.0	4499.0
VAV2	-4959.0	2847.0
VAV3	187.0	-276.0
VCAM1	2866.0	4602.0
VCL	-4538.0	5383.0
VEGFA	-4571.0	-5070.0
VIM	-3027.0	5076.0
VPRBP	847.0	2862.0
VRK3	464.0	3294.0
VWF	-779.0	1730.0
WASF2	-4656.0	3026.0
WASF3	-1015.0	1293.0
WASL	2683.0	4511.0
WDR83	1010.0	-3938.0
WIPF1	-2552.0	2457.0
WIPF2	3299.0	-608.0
WIPF3	-5107.0	-4936.0
WSB1	-3737.0	4817.0
WWP1	-1200.0	-3658.0
XAF1	-320.0	-184.0
XRCC5	4010.0	1456.0
XRCC6	3225.0	-2097.0
YES1	-176.0	-836.0
YPEL5	4366.0	4902.0
YWHAB	3680.0	3468.0
YWHAZ	2019.0	4919.0
ZBTB16	-4334.0	-547.0
ZDHHC9	-3396.0	2752.0
ZEB1	-4223.0	3785.0
ZNRF1	-4109.0	-2540.0
ZNRF2	-2152.0	-858.0

---

---

Mitochondrial protein import

Mitochondrial protein import

metric	value
setSize	55
pMANOVA	5.13e-14
p.adjustMANOVA	2.87e-12
s.dist	0.602
s.human	-0.00782
s.mouse	-0.602
p.human	0.92
p.mouse	1.19e-14

Top 20 genes

Gene	human	mouse
SLC25A12	-5347	-4761
CHCHD10	-4902	-3931
TAZ	-3604	-4956
CYC1	-4147	-4292
ACO2	-3822	-4534
IDH3G	-4178	-3714
NDUFB8	-3020	-4892
VDAC1	-2909	-4782
LDHD	-5163	-2192
TIMM17B	-3141	-2749
TIMM13	-3591	-2117
PAM16	-2464	-2969
FXN	-2179	-3293
TOMM7	-1885	-3378
SLC25A4	-1327	-4427
TIMM44	-1151	-5068
COQ2	-1700	-3133
CHCHD4	-2167	-2361
GRPEL1	-2346	-2045
BCS1L	-1023	-4605

Click HERE to show all gene set members

All member genes

	human	mouse
ACO2	-3822	-4534
BCS1L	-1023	-4605
CHCHD10	-4902	-3931
CHCHD2	446	-3053
CHCHD3	123	-3496
CHCHD4	-2167	-2361
CHCHD5	-2111	-2033
CHCHD7	2643	-1066
CMC2	3597	-4660
COA4	-3800	-973
COA6	4111	-3650
COQ2	-1700	-3133
COX17	-2094	-1938
COX19	3053	2889
CS	3653	-4328
CYC1	-4147	-4292
DNAJC19	1118	-4186
FXN	-2179	-3293
GFER	-3119	-1243
GRPEL1	-2346	-2045
GRPEL2	1127	1067
HSCB	-134	-1814
HSPA9	2342	-3484
HSPD1	-855	-3145
IDH3G	-4178	-3714
LDHD	-5163	-2192
MTX1	2018	-1987
MTX2	52	-2397
NDUFB8	-3020	-4892
PAM16	-2464	-2969
PITRM1	582	-1790
PMPCA	-92	-3017
PMPCB	-832	-4741
SAMM50	1141	-4536
SLC25A12	-5347	-4761
SLC25A13	4283	2507
SLC25A4	-1327	-4427
TAZ	-3604	-4956
TIMM10	179	-2702
TIMM10B	4307	-4902
TIMM13	-3591	-2117
TIMM17A	2548	-4167
TIMM17B	-3141	-2749
TIMM21	1825	-4898
TIMM22	1561	-3223
TIMM44	-1151	-5068
TIMM50	987	-2561
TIMM8B	-658	-3816
TIMM9	690	-3965
TOMM20	2711	101
TOMM22	2828	-2447
TOMM40	4211	-1560
TOMM5	2707	-4232
TOMM7	-1885	-3378
VDAC1	-2909	-4782

---

---

Cell Cycle

Cell Cycle

metric	value
setSize	484
pMANOVA	1.1e-13
p.adjustMANOVA	5.87e-12
s.dist	0.222
s.human	0.193
s.mouse	0.11
p.human	7.18e-13
p.mouse	4.51e-05

Top 20 genes

Gene	human	mouse
PPME1	4727	5508
NUP98	4235	5486
FBXW11	4385	5178
RAD21	4417	4961
BRCA2	4886	4402
NUP54	4508	4751
POLR2A	3861	5366
CHTF8	3753	5511
HSP90AA1	3656	5525
CDC25B	4652	4269
DBF4	4260	4558
CEP152	4492	4285
NUP153	4762	4031
EML4	4736	4004
RAB1A	3634	5087
HAUS3	3748	4846
MAPRE1	3454	5215
PPP2R5A	4590	3889
SKP2	4205	4241
CCNE1	4388	4060

Click HERE to show all gene set members

All member genes

	human	mouse
AAAS	-3476	40.0
ABL1	-4533	1377.0
ACD	-1324	-1105.0
ACTR1A	-4126	3959.0
AHCTF1	4662	2760.0
AJUBA	-4112	-1867.0
AKAP9	-573	-4367.0
AKT1	-4954	1242.0
AKT2	-4057	-3488.0
AKT3	1343	2419.0
ALMS1	4347	1257.0
ANAPC1	572	-470.0
ANAPC10	1974	2927.0
ANAPC11	-3265	-2502.0
ANAPC15	-3393	1658.0
ANAPC16	-3612	-3229.0
ANAPC2	-2185	-1142.0
ANAPC4	-720	-3761.0
ANAPC5	1284	-3105.0
ANAPC7	1595	882.0
ANKLE2	1499	366.0
ANKRD28	1927	-3829.0
ARPP19	2927	3170.0
ATM	1449	-3358.0
ATR	1983	1782.0
ATRX	3995	13.0
AURKA	3811	-2443.0
B9D2	1676	-3727.0
BABAM1	-1363	-2121.0
BANF1	-2281	-1690.0
BLM	1103	4665.0
BLZF1	4266	-284.0
BORA	4768	2662.0
BRCA2	4886	4402.0
BRCC3	-375	-2352.0
BRE	696	-2050.0
BTRC	-1187	-2761.0
BUB3	4201	-1316.0
CABLES1	-4484	662.0
CC2D1B	1025	2921.0
CCNA2	3061	2333.0
CCND1	757	1643.0
CCND2	225	2762.0
CCND3	786	1243.0
CCNE1	4388	4060.0
CCNE2	4667	-521.0
CCNH	3825	-1939.0
CCP110	4605	2327.0
CDC14A	957	-850.0
CDC16	86	-1235.0
CDC23	3850	1048.0
CDC25A	4090	3965.0
CDC25B	4652	4269.0
CDC26	2750	2001.0
CDC27	665	3905.0
CDC7	2421	3646.0
CDK1	1580	3204.0
CDK11A	167	-1445.5
CDK11B	1690	-1445.5
CDK2	849	2902.0
CDK4	703	2603.0
CDK5RAP2	-3037	414.0
CDK6	1090	2660.0
CDK7	1571	326.0
CDKN1A	-4927	3046.0
CDKN1B	-3284	-2637.0
CDKN1C	-5394	-2348.0
CDKN2B	-2827	-832.0
CDKN2C	3612	259.0
CDKN2D	142	-206.0
CENPC	3555	-133.0
CENPJ	1720	200.0
CENPL	3768	3397.0
CENPO	1005	3332.0
CENPQ	1344	5114.0
CENPT	-2196	4477.0
CEP135	1891	-215.0
CEP152	4492	4285.0
CEP164	3699	4174.0
CEP192	2073	659.0
CEP250	3192	-2201.0
CEP290	3352	-1031.0
CEP41	4357	2959.0
CEP57	611	-1339.0
CEP63	-2491	-3687.0
CEP70	-3094	-1341.0
CEP76	3163	4149.0
CEP78	3895	2253.0
CETN2	-587	-1606.0
CHEK2	1311	-33.0
CHMP2A	1155	2070.0
CHMP2B	967	-4699.0
CHMP3	-3919	1246.0
CHMP4B	-1125	-1336.0
CHMP6	-4368	-1833.0
CHMP7	1743	-1108.0
CHTF8	3753	5511.0
CKAP5	-3973	78.0
CKS1B	1446	4954.0
CLASP1	-3713	3198.0
CLASP2	2507	2478.0
CLIP1	418	-371.0
CNEP1R1	1729	379.0
CNTRL	4333	-4470.0
CSNK1D	-3539	4717.0
CSNK1E	-5045	3424.0
CSNK2A1	1796	-2551.0
CSNK2A2	2123	2667.0
CSNK2B	1917	-1746.0
CTC1	1689	-887.0
CTDNEP1	-2509	-3777.0
CUL1	-3121	-833.0
DAXX	4449	3854.0
DBF4	4260	4558.0
DCTN1	-347	-4056.0
DCTN2	-3157	-3324.0
DCTN3	-943	1919.0
DHFR	-3638	2914.5
DIDO1	1299	694.0
DKC1	3629	1648.0
DNA2	37	3262.0
DSN1	2075	-665.0
DYNC1H1	-1442	1264.0
DYNC1I2	2591	172.0
DYNC1LI1	2883	981.0
DYNC1LI2	1750	3473.0
DYNLL1	-1331	3935.0
DYRK1A	-2401	4754.0
E2F1	-529	4887.0
E2F3	-4683	2636.0
E2F4	-439	4952.0
E2F5	-249	1172.0
E2F6	650	-3961.0
EMD	-651	533.0
EML4	4736	4004.0
ENSA	-114	-163.0
EP300	3403	2309.0
ESCO1	680	-926.0
ESPL1	408	4532.0
FAM175A	-3897	-1211.0
FBXL18	1610	-956.0
FBXW11	4385	5178.0
FEN1	4094	-1467.0
FKBPL	4474	3796.0
FZR1	-1244	3161.0
GAR1	4132	4232.0
GINS1	441	-336.0
GINS3	-1006	2153.0
GINS4	-1475	-1141.0
GMNN	4714	-3302.0
GOLGA2	919	-3694.0
GORASP1	-4615	-2930.0
GORASP2	2697	5074.0
GSK3B	897	4692.0
H2AFX	2356	5181.0
HAUS1	1263	-754.0
HAUS2	2905	3427.0
HAUS3	3748	4846.0
HAUS4	-2191	-1521.0
HAUS6	3590	2060.0
HAUS8	758	3827.0
HDAC8	209	-3383.0
HSP90AA1	3656	5525.0
HSP90AB1	-639	5203.0
HSPA2	4948	2571.0
HUS1	2435	-1222.0
INCENP	3676	1455.0
IST1	3827	3890.0
ITGB3BP	1048	-2794.0
JAK2	-2569	-2171.0
KAT5	447	1402.0
KIF18A	3832	2448.0
KIF23	1216	2656.0
KIF2A	-4390	4073.0
KPNB1	3619	4744.0
LBR	2244	-878.0
LCMT1	729	-2516.0
LEMD2	-1073	-727.0
LEMD3	3330	789.0
LIG1	-3127	898.0
LIN37	-1988	3202.0
LIN52	915	-3656.0
LIN54	4080	-750.0
LIN9	1166	-3476.0
LMNA	-4692	5452.0
LMNB1	3392	648.0
LPIN1	-2877	-4450.0
LPIN2	3569	3805.0
LPIN3	-1052	2283.0
LYN	785	2842.0
MAD1L1	-3382	1367.0
MAD2L1	1101	1981.0
MAPK1	1988	-969.0
MAPK3	-1024	4464.0
MAPRE1	3454	5215.0
MAU2	-3188	439.0
MAX	-2352	-1748.0
MCM2	-3977	-144.0
MCM3	600	4066.0
MCM4	-610	4411.0
MCM5	-1490	4615.0
MCM6	3462	4930.0
MCM7	2515	864.0
MCM8	-3355	-4264.0
MCPH1	2176	571.0
MDC1	841	2652.0
MDM2	3253	5156.0
MDM4	2051	-1866.0
MIS12	2400	5092.0
MIS18A	4613	610.0
MLH1	-1210	-3920.0
MLH3	-407	-3582.0
MNAT1	830	-3106.0
MYC	3994	185.0
MZT1	3517	-3577.0
MZT2A	-3883	-2755.5
MZT2B	-3442	-2755.5
NBN	1286	-1789.0
NCAPD2	4017	-3639.0
NCAPD3	3002	-4465.0
NCAPG2	-13	-219.0
NCAPH	1129	2968.0
NCAPH2	-1845	-165.0
NDC1	1273	-322.0
NDE1	4322	-1640.0
NDEL1	4631	3278.0
NEDD1	1034	-212.0
NEK6	-5042	3707.0
NEK7	535	-1025.0
NEK9	-2856	1690.0
NHP2	694	1773.0
NIPBL	4675	-1061.0
NME7	2020	722.0
NOP10	1336	-894.0
NUDC	3212	-860.0
NUMA1	-4395	143.0
NUP107	3232	3195.0
NUP133	889	-2580.0
NUP153	4762	4031.0
NUP155	4306	2897.0
NUP160	3998	2314.0
NUP188	2117	4593.0
NUP205	4438	3917.0
NUP214	3124	1845.0
NUP35	4571	2515.0
NUP37	-327	-873.0
NUP43	4562	193.0
NUP54	4508	4751.0
NUP85	3181	227.0
NUP88	1244	1407.0
NUP93	-1503	5229.0
NUP98	4235	5486.0
ODF2	1954	1134.0
OFD1	811	-1859.0
OPTN	1980	-1444.0
ORC2	1022	5065.0
ORC3	-1627	-3647.0
ORC4	3929	2552.0
ORC5	4429	-1666.0
ORC6	2184	-3079.0
PAFAH1B1	-2026	1737.0
PCBP4	-5523	-200.0
PCM1	1788	-1831.0
PCNA	1329	5271.0
PCNT	-1269	-5032.0
PDS5A	1248	976.0
PDS5B	-3191	-2058.0
PHF20	819	949.0
PHF8	3393	1834.0
PHLDA1	-3126	5172.0
PIAS4	342	-629.0
PLK4	3581	2637.0
POLA1	1944	2596.0
POLA2	-173	-4473.0
POLD1	-3218	-1289.0
POLD2	-4806	-1924.0
POLD3	3486	1800.0
POLD4	-2084	3734.0
POLE	-3659	1758.0
POLE2	1264	2303.0
POLE3	4335	3627.0
POLE4	409	2317.0
POLR2A	3861	5366.0
POLR2B	4509	-3401.0
POLR2C	4529	-4002.0
POLR2D	1669	3230.0
POLR2E	-667	148.0
POLR2G	89	4349.0
POLR2H	-3927	2213.0
POLR2I	-154	-2504.0
POLR2K	2480	-3599.0
POLR2L	-4314	-1126.0
POT1	3936	-1252.0
PPME1	4727	5508.0
PPP1CB	-1374	-3335.0
PPP1CC	4081	-1627.0
PPP1R12A	4131	4053.0
PPP1R12B	-5005	2701.0
PPP2CA	4482	1672.0
PPP2CB	2458	2352.0
PPP2R1A	-4013	-681.0
PPP2R1B	3028	3194.0
PPP2R2A	2264	1164.0
PPP2R2D	-2153	1214.0
PPP2R5A	4590	3889.0
PPP2R5B	-1524	-765.0
PPP2R5C	-2508	-293.0
PPP2R5D	-3449	-620.0
PPP2R5E	4644	2107.0
PPP6C	3109	-349.0
PPP6R3	3079	3705.0
PRIM1	311	3175.0
PRIM2	3544	3971.0
PRKACA	-4691	-4303.0
PRKAR2B	3460	1006.0
PRKCA	-2938	1125.0
PSMA1	2820	4043.0
PSMA3	3434	-1035.0
PSMA4	769	-1962.0
PSMA6	2199	-1657.0
PSMA7	-2980	-1038.0
PSMB1	954	-1037.0
PSMB10	-1800	-831.0
PSMB2	618	-67.0
PSMB4	-235	-559.0
PSMB5	-4113	-2597.0
PSMB6	-793	-1795.0
PSMB7	-831	-2699.0
PSMB8	-675	-2510.0
PSMB9	-1611	-3558.0
PSMC1	449	1146.0
PSMC2	-1311	3386.0
PSMC3	-2439	-1846.0
PSMC3IP	2987	-735.0
PSMC4	2724	-205.0
PSMC5	1212	-1680.0
PSMC6	-2520	3114.0
PSMD1	2619	3210.0
PSMD10	-1227	361.0
PSMD11	995	5504.0
PSMD12	3831	-462.0
PSMD13	821	532.0
PSMD14	-635	3746.0
PSMD2	-713	741.0
PSMD3	-3343	-354.0
PSMD4	-214	968.0
PSMD5	1807	4479.0
PSMD6	3537	-3784.0
PSMD7	-2329	410.0
PSMD8	-3171	4292.0
PSMD9	4204	-3586.0
PSME1	-2771	-2861.0
PSME2	-4085	-41.0
PSME3	3333	491.0
PSME4	1960	2319.0
PSMF1	683	-1768.0
PTTG1	4843	-4670.0
RAB1A	3634	5087.0
RAB1B	-2997	-3742.0
RAB2A	1999	-1496.0
RAB8A	3378	3986.0
RAD1	3205	3596.0
RAD17	2273	-1057.0
RAD21	4417	4961.0
RAD50	306	-1413.0
RAD51	63	-3321.0
RAD9A	-3149	-726.0
RAE1	4471	3078.0
RAN	2329	575.0
RANBP2	4470	-562.0
RANGAP1	483	4468.0
RB1	-2449	831.0
RBBP4	1072	728.0
RBBP7	-924	-1007.0
RBBP8	3047	3887.0
RBL1	-1617	-993.0
RBL2	-242	-1988.0
RBX1	-733	-2400.0
RCC1	997	4917.0
RCC2	4178	3180.0
RFC1	4641	2623.0
RFC2	622	-3123.0
RFC3	2151	3463.0
RFC4	3542	-36.0
RFC5	1409	3702.0
RFWD2	2172	601.0
RHNO1	-4573	-260.0
RMI1	4517	1974.0
RMI2	-2759	-2576.0
RNF168	4346	3019.0
RNF8	975	-678.0
RPA1	-1837	-2287.0
RPA2	2889	-3725.0
RPA3	2702	-4228.0
RPS27A	783	-2165.0
RSF1	951	2210.0
RUVBL1	-1240	-1693.0
RUVBL2	-2543	1091.0
SDCCAG8	1021	2266.0
SEC13	730	938.0
SEH1L	1085	4110.0
SET	3683	1612.0
SFI1	-1212	-3175.0
SHQ1	3320	1288.0
SIRT2	-4852	-682.0
SKA2	2399	946.0
SKP1	2028	-1286.0
SKP2	4205	4241.0
SMARCA5	4439	1177.0
SMC1A	3824	-118.0
SMC2	2477	3897.0
SMC3	4878	2611.0
SMC4	4127	1198.0
SPAST	3456	-976.0
SRC	-3910	3763.0
SSNA1	-2879	-2145.0
STAG1	4246	505.0
STAG2	31	-897.0
STRA13	-1061	-1281.0
SUMO1	4213	-262.0
SUN1	-4018	526.0
SUN2	-5310	-3315.0
SYNE1	-4982	757.0
SYNE2	1402	-3263.0
TAOK1	1644	130.0
TERF1	422	-545.0
TERF2	-1834	791.0
TERF2IP	4692	1040.0
TFDP1	-2245	-3110.0
TFDP2	4029	-4963.0
TINF2	-1257	-2884.0
TK1	-3225	-65.0
TMPO	4574	-1098.0
TNPO1	3184	5474.0
TOP2A	4691	3074.0
TOP3A	2607	3192.0
TOPBP1	2183	5010.0
TP53	575	3128.0
TP53BP1	-643	4622.0
TPR	2984	275.0
TPX2	3446	2866.0
TUBA1A	-5228	4221.0
TUBA1B	-5324	5343.0
TUBA1C	-4883	5415.0
TUBA4A	-5342	240.0
TUBA8	-1116	-946.0
TUBB	-3118	5321.0
TUBB2A	-4676	5002.0
TUBB2B	-4704	5335.0
TUBB4B	430	4642.0
TUBB6	-5060	5524.0
TUBG1	-3728	-3871.0
TUBG2	93	-148.0
TUBGCP2	-3362	-2968.0
TUBGCP3	2352	2516.0
TUBGCP4	4074	1836.0
TUBGCP6	-3953	-1591.0
TYMS	-2042	3786.0
UBC	2672	3877.0
UBE2C	4949	-3635.0
UBE2D1	-1588	-4657.0
UBE2E1	-1132	-881.0
UBE2I	1246	733.0
UBE2N	2545	4245.0
UBE2S	4441	2868.0
UBE2V2	-334	2814.0
UIMC1	835	-1148.0
USO1	-738	3388.0
VPS4A	-1545	-2729.0
VRK1	1696	-3373.0
VRK2	1461	-4163.0
WEE1	-4561	3159.0
WRAP53	1081	371.0
WRN	98	2942.0
XPO1	990	2133.0
YWHAB	3680	3468.0
YWHAE	1394	-2051.0
YWHAG	-2372	1012.0
YWHAH	-2777	3808.0
YWHAQ	963	3949.0
YWHAZ	2019	4919.0
ZNF385A	-5211	2561.0
ZW10	1474	3364.0
ZWINT	2778	5457.0

---

---

rRNA modification in the nucleus and cytosol

rRNA modification in the nucleus and cytosol

metric	value
setSize	52
pMANOVA	1.37e-13
p.adjustMANOVA	7.04e-12
s.dist	0.649
s.human	0.6
s.mouse	0.247
p.human	7.07e-14
p.mouse	0.00209

Top 20 genes

Gene	human	mouse
HEATR1	4911	5214.0
UTP14A	4777	5328.5
WDR43	4883	4985.0
DCAF13	4800	4904.0
WDR3	4838	4572.0
NOP58	4891	3903.0
NOL6	3819	4849.0
NOP2	3472	5052.0
GAR1	4132	4232.0
WDR75	3743	3744.0
UTP3	4917	2335.0
IMP4	2805	4037.0
NOP56	3099	3605.0
MPHOSPH10	3928	2821.0
WDR36	4542	2424.0
WDR46	3335	3009.0
NAT10	3642	2679.0
NOL11	4916	1935.0
DDX49	2178	4308.0
RRP7A	2138	4236.0

Click HERE to show all gene set members

All member genes

	human	mouse
BMS1	3511	-3149.0
DCAF13	4800	4904.0
DDX47	3735	-2506.0
DDX49	2178	4308.0
DHX37	2105	3594.0
DIEXF	4877	-510.0
DIMT1	2537	42.0
DKC1	3629	1648.0
FBL	4233	-132.0
FCF1	3303	1429.0
GAR1	4132	4232.0
HEATR1	4911	5214.0
IMP3	4536	-4210.0
IMP4	2805	4037.0
KRR1	3921	-1381.0
MPHOSPH10	3928	2821.0
NAT10	3642	2679.0
NHP2	694	1773.0
NOC4L	1763	-2682.0
NOL11	4916	1935.0
NOL6	3819	4849.0
NOP10	1336	-894.0
NOP14	1590	4297.0
NOP2	3472	5052.0
NOP56	3099	3605.0
NOP58	4891	3903.0
PDCD11	-1465	862.0
PNO1	4623	-406.0
PWP2	2462	1711.0
RCL1	3257	237.0
RPS14	-1412	122.0
RPS6	-245	1237.0
RPS9	-1107	-2477.0
RRP36	1532	29.0
RRP7A	2138	4236.0
RRP9	771	1609.0
TBL3	-1551	3495.0
THUMPD1	4666	-558.0
TSR3	-3611	-4069.0
UTP14A	4777	5328.5
UTP14C	1565	5328.5
UTP15	4137	-396.0
UTP18	3851	2069.0
UTP20	4174	832.0
UTP3	4917	2335.0
UTP6	4779	-1773.0
WBSCR22	1741	-4222.0
WDR3	4838	4572.0
WDR36	4542	2424.0
WDR43	4883	4985.0
WDR46	3335	3009.0
WDR75	3743	3744.0

---

---

rRNA processing in the nucleus and cytosol

rRNA processing in the nucleus and cytosol

metric	value
setSize	143
pMANOVA	3.08e-13
p.adjustMANOVA	1.52e-11
s.dist	0.38
s.human	0.367
s.mouse	0.0976
p.human	4.03e-14
p.mouse	0.0447

Top 20 genes

Gene	human	mouse
DDX21	4868	5307.0
HEATR1	4911	5214.0
UTP14A	4777	5328.5
WDR43	4883	4985.0
DCAF13	4800	4904.0
WDR3	4838	4572.0
NOP58	4891	3903.0
NOL6	3819	4849.0
FTSJ3	4444	4129.0
EXOSC10	4991	3582.0
LTV1	4806	3706.0
NOP2	3472	5052.0
GAR1	4132	4232.0
GNL3	4434	3896.0
ISG20L2	3385	4842.0
TSR1	3117	5039.0
NCL	3573	4049.0
WDR75	3743	3744.0
DIS3	4973	2795.0
XRN2	4296	3178.0

Click HERE to show all gene set members

All member genes

	human	mouse
BMS1	3511	-3149.0
BYSL	2701	1718.0
C1D	3347	-1555.0
CSNK1D	-3539	4717.0
CSNK1E	-5045	3424.0
DCAF13	4800	4904.0
DDX21	4868	5307.0
DDX47	3735	-2506.0
DDX49	2178	4308.0
DHX37	2105	3594.0
DIEXF	4877	-510.0
DIMT1	2537	42.0
DIS3	4973	2795.0
DKC1	3629	1648.0
EBNA1BP2	4030	-1624.0
ERI1	2910	2565.0
EXOSC1	1073	3516.0
EXOSC10	4991	3582.0
EXOSC2	3309	2709.0
EXOSC3	3331	784.0
EXOSC4	2447	-3953.0
EXOSC5	20	-4477.0
EXOSC7	-4980	-1705.0
EXOSC8	3102	1509.0
EXOSC9	4106	-1160.0
FAU	2272	2649.0
FBL	4233	-132.0
FCF1	3303	1429.0
FTSJ3	4444	4129.0
GAR1	4132	4232.0
GNL3	4434	3896.0
HEATR1	4911	5214.0
IMP3	4536	-4210.0
IMP4	2805	4037.0
ISG20L2	3385	4842.0
KRR1	3921	-1381.0
LAS1L	3707	-585.0
LTV1	4806	3706.0
MPHOSPH10	3928	2821.0
MPHOSPH6	2298	-1743.0
NAT10	3642	2679.0
NCL	3573	4049.0
NHP2	694	1773.0
NIP7	3751	2356.0
NOB1	3229	2731.0
NOC4L	1763	-2682.0
NOL11	4916	1935.0
NOL6	3819	4849.0
NOL9	4679	688.0
NOP10	1336	-894.0
NOP14	1590	4297.0
NOP2	3472	5052.0
NOP56	3099	3605.0
NOP58	4891	3903.0
PDCD11	-1465	862.0
PELP1	2605	1451.0
PES1	4214	1923.0
PNO1	4623	-406.0
PWP2	2462	1711.0
RBM28	4327	-99.0
RCL1	3257	237.0
RIOK1	3760	-572.0
RIOK3	-1480	1085.0
RPL10	-3902	3923.0
RPL11	-2249	-1971.0
RPL14	433	-875.0
RPL18	-1782	448.0
RPL18A	-2969	-320.0
RPL19	-502	-1379.0
RPL22	1231	-3446.0
RPL22L1	3380	2374.0
RPL23	-115	-2882.0
RPL26	1047	696.0
RPL28	-391	-1891.0
RPL3	-786	5412.0
RPL30	286	-3056.0
RPL31	-595	2894.0
RPL32	-367	-950.0
RPL34	1447	-1314.0
RPL35A	812	-1471.0
RPL36A	1261	-1408.0
RPL37	-715	-1311.0
RPL37A	-1043	554.0
RPL38	231	-953.0
RPL3L	-5212	-4614.0
RPL4	-522	-571.0
RPL5	1206	3360.0
RPL7	1440	-1894.0
RPL8	-2775	-928.0
RPLP2	-2469	-3389.0
RPP14	2370	-2951.0
RPP30	2968	1603.0
RPP38	3980	480.0
RPP40	3369	-2381.0
RPS11	-1582	-458.0
RPS12	-318	1501.0
RPS13	1131	-1994.0
RPS14	-1412	122.0
RPS15	-1799	-1082.0
RPS15A	-704	-237.0
RPS16	-1828	2010.0
RPS18	-974	-1404.0
RPS19	-2045	-882.0
RPS20	-1844	1712.0
RPS21	-1536	-2810.0
RPS23	-68	-749.0
RPS24	256	-1505.0
RPS26	-282	-1421.0
RPS27A	783	-2165.0
RPS27L	-616	-69.0
RPS29	-1140	-1275.0
RPS3	-544	116.0
RPS4X	83	97.0
RPS5	-1577	935.0
RPS6	-245	1237.0
RPS8	-1593	-1231.0
RPS9	-1107	-2477.0
RRP1	1063	-4885.0
RRP36	1532	29.0
RRP7A	2138	4236.0
RRP9	771	1609.0
SENP3	2112	2776.0
TBL3	-1551	3495.0
TEX10	2840	3253.0
THUMPD1	4666	-558.0
TSR1	3117	5039.0
TSR3	-3611	-4069.0
UTP14A	4777	5328.5
UTP14C	1565	5328.5
UTP15	4137	-396.0
UTP18	3851	2069.0
UTP20	4174	832.0
UTP3	4917	2335.0
UTP6	4779	-1773.0
WBSCR22	1741	-4222.0
WDR12	1739	-1129.0
WDR18	-812	-3151.0
WDR3	4838	4572.0
WDR36	4542	2424.0
WDR43	4883	4985.0
WDR46	3335	3009.0
WDR75	3743	3744.0
XRN2	4296	3178.0

---

---

HIV Life Cycle

HIV Life Cycle

metric	value
setSize	122
pMANOVA	6.45e-13
p.adjustMANOVA	3.06e-11
s.dist	0.424
s.human	0.349
s.mouse	0.24
p.human	2.98e-11
p.mouse	4.84e-06

Top 20 genes

Gene	human	mouse
TAF4B	4967	5489
TAF7	4717	5281
GTF2B	4276	5493
NUP98	4235	5486
GTF2F1	4999	4439
NUP54	4508	4751
POLR2A	3861	5366
GTF2F2	4067	5047
GTF2A1	4730	4204
NUP153	4762	4031
RNMT	4864	3622
TAF3	4294	4087
NUP205	4438	3917
VPS4B	4523	3841
SUPT16H	3885	4417
TAF2	4591	3536
RAE1	4471	3078
NUP155	4306	2897
TAF12	3100	3716
NUP35	4571	2515

Click HERE to show all gene set members

All member genes

	human	mouse
AAAS	-3476	40.0
BANF1	-2281	-1690.0
CCNH	3825	-1939.0
CCNK	3139	-346.0
CCNT1	4896	309.0
CCNT2	4381	-4634.0
CDK7	1571	326.0
CDK9	-1348	4755.0
CHMP2A	1155	2070.0
CHMP2B	967	-4699.0
CHMP3	-3919	1246.0
CHMP4B	-1125	-1336.0
CHMP5	3372	-1350.0
CHMP6	-4368	-1833.0
CHMP7	1743	-1108.0
CTDP1	2071	4946.0
ELL	-3990	3539.0
ERCC2	824	4319.0
ERCC3	473	3200.0
FEN1	4094	-1467.0
FURIN	-4221	4897.0
GTF2A1	4730	4204.0
GTF2A2	4648	-2956.0
GTF2B	4276	5493.0
GTF2E1	2188	896.0
GTF2E2	2041	-136.0
GTF2F1	4999	4439.0
GTF2F2	4067	5047.0
GTF2H1	3886	647.0
GTF2H2	4419	-2426.5
GTF2H3	-1925	-664.0
GTF2H5	-878	-3245.0
HMGA1	598	5468.0
KPNA1	1833	4786.0
LIG1	-3127	898.0
LIG4	2394	-1960.0
MNAT1	830	-3106.0
MVB12A	-2807	-2371.0
MVB12B	-5576	-1428.0
NCBP1	-1736	4720.0
NCBP2	4188	-2519.0
NDC1	1273	-322.0
NEDD4L	4279	95.0
NELFA	356	3429.0
NELFB	-1196	2017.0
NELFCD	1896	-2826.0
NELFE	-2178	3913.0
NMT1	-1463	4510.0
NMT2	2059	4895.0
NUP107	3232	3195.0
NUP133	889	-2580.0
NUP153	4762	4031.0
NUP155	4306	2897.0
NUP160	3998	2314.0
NUP188	2117	4593.0
NUP205	4438	3917.0
NUP214	3124	1845.0
NUP35	4571	2515.0
NUP37	-327	-873.0
NUP43	4562	193.0
NUP54	4508	4751.0
NUP85	3181	227.0
NUP88	1244	1407.0
NUP93	-1503	5229.0
NUP98	4235	5486.0
PDCD6IP	1350	5265.0
POLR2A	3861	5366.0
POLR2B	4509	-3401.0
POLR2C	4529	-4002.0
POLR2D	1669	3230.0
POLR2E	-667	148.0
POLR2G	89	4349.0
POLR2H	-3927	2213.0
POLR2I	-154	-2504.0
POLR2K	2480	-3599.0
POLR2L	-4314	-1126.0
PPIA	-4031	4207.0
PSIP1	3390	1448.0
RAE1	4471	3078.0
RAN	2329	575.0
RANBP1	745	3863.0
RANBP2	4470	-562.0
RANGAP1	483	4468.0
RCC1	997	4917.0
RNGTT	4414	-1456.0
RNMT	4864	3622.0
RPS27A	783	-2165.0
SEC13	730	938.0
SEH1L	1085	4110.0
SSRP1	1755	1765.0
SUPT16H	3885	4417.0
SUPT4H1	3648	-1692.0
SUPT5H	1321	4377.0
TAF1	1708	4363.0
TAF10	-273	547.0
TAF11	2962	-1678.0
TAF12	3100	3716.0
TAF13	4749	1646.0
TAF2	4591	3536.0
TAF3	4294	4087.0
TAF4	-1340	4027.0
TAF4B	4967	5489.0
TAF5	4309	1473.0
TAF6	-912	-885.0
TAF7	4717	5281.0
TAF9B	1874	-618.0
TBP	1137	3931.0
TCEA1	4037	163.0
TPR	2984	275.0
TSG101	260	1656.0
UBAP1	-1913	5312.0
UBC	2672	3877.0
VPS37A	1868	1922.0
VPS37B	-3496	3692.0
VPS37C	1403	3199.0
VPS4A	-1545	-2729.0
VPS4B	4523	3841.0
VTA1	3283	591.0
XPO1	990	2133.0
XRCC4	-4731	333.0
XRCC5	4010	1456.0
XRCC6	3225	-2097.0

---

---

Late Phase of HIV Life Cycle

Late Phase of HIV Life Cycle

metric	value
setSize	112
pMANOVA	9.97e-13
p.adjustMANOVA	4.55e-11
s.dist	0.439
s.human	0.359
s.mouse	0.253
p.human	5.75e-11
p.mouse	3.97e-06

Top 20 genes

Gene	human	mouse
TAF4B	4967	5489
TAF7	4717	5281
GTF2B	4276	5493
NUP98	4235	5486
GTF2F1	4999	4439
NUP54	4508	4751
POLR2A	3861	5366
GTF2F2	4067	5047
GTF2A1	4730	4204
NUP153	4762	4031
RNMT	4864	3622
TAF3	4294	4087
NUP205	4438	3917
VPS4B	4523	3841
SUPT16H	3885	4417
TAF2	4591	3536
RAE1	4471	3078
NUP155	4306	2897
TAF12	3100	3716
NUP35	4571	2515

Click HERE to show all gene set members

All member genes

	human	mouse
AAAS	-3476	40.0
CCNH	3825	-1939.0
CCNK	3139	-346.0
CCNT1	4896	309.0
CCNT2	4381	-4634.0
CDK7	1571	326.0
CDK9	-1348	4755.0
CHMP2A	1155	2070.0
CHMP2B	967	-4699.0
CHMP3	-3919	1246.0
CHMP4B	-1125	-1336.0
CHMP5	3372	-1350.0
CHMP6	-4368	-1833.0
CHMP7	1743	-1108.0
CTDP1	2071	4946.0
ELL	-3990	3539.0
ERCC2	824	4319.0
ERCC3	473	3200.0
FURIN	-4221	4897.0
GTF2A1	4730	4204.0
GTF2A2	4648	-2956.0
GTF2B	4276	5493.0
GTF2E1	2188	896.0
GTF2E2	2041	-136.0
GTF2F1	4999	4439.0
GTF2F2	4067	5047.0
GTF2H1	3886	647.0
GTF2H2	4419	-2426.5
GTF2H3	-1925	-664.0
GTF2H5	-878	-3245.0
MNAT1	830	-3106.0
MVB12A	-2807	-2371.0
MVB12B	-5576	-1428.0
NCBP1	-1736	4720.0
NCBP2	4188	-2519.0
NDC1	1273	-322.0
NEDD4L	4279	95.0
NELFA	356	3429.0
NELFB	-1196	2017.0
NELFCD	1896	-2826.0
NELFE	-2178	3913.0
NMT1	-1463	4510.0
NMT2	2059	4895.0
NUP107	3232	3195.0
NUP133	889	-2580.0
NUP153	4762	4031.0
NUP155	4306	2897.0
NUP160	3998	2314.0
NUP188	2117	4593.0
NUP205	4438	3917.0
NUP214	3124	1845.0
NUP35	4571	2515.0
NUP37	-327	-873.0
NUP43	4562	193.0
NUP54	4508	4751.0
NUP85	3181	227.0
NUP88	1244	1407.0
NUP93	-1503	5229.0
NUP98	4235	5486.0
PDCD6IP	1350	5265.0
POLR2A	3861	5366.0
POLR2B	4509	-3401.0
POLR2C	4529	-4002.0
POLR2D	1669	3230.0
POLR2E	-667	148.0
POLR2G	89	4349.0
POLR2H	-3927	2213.0
POLR2I	-154	-2504.0
POLR2K	2480	-3599.0
POLR2L	-4314	-1126.0
PPIA	-4031	4207.0
RAE1	4471	3078.0
RAN	2329	575.0
RANBP1	745	3863.0
RANBP2	4470	-562.0
RANGAP1	483	4468.0
RCC1	997	4917.0
RNGTT	4414	-1456.0
RNMT	4864	3622.0
RPS27A	783	-2165.0
SEC13	730	938.0
SEH1L	1085	4110.0
SSRP1	1755	1765.0
SUPT16H	3885	4417.0
SUPT4H1	3648	-1692.0
SUPT5H	1321	4377.0
TAF1	1708	4363.0
TAF10	-273	547.0
TAF11	2962	-1678.0
TAF12	3100	3716.0
TAF13	4749	1646.0
TAF2	4591	3536.0
TAF3	4294	4087.0
TAF4	-1340	4027.0
TAF4B	4967	5489.0
TAF5	4309	1473.0
TAF6	-912	-885.0
TAF7	4717	5281.0
TAF9B	1874	-618.0
TBP	1137	3931.0
TCEA1	4037	163.0
TPR	2984	275.0
TSG101	260	1656.0
UBAP1	-1913	5312.0
UBC	2672	3877.0
VPS37A	1868	1922.0
VPS37B	-3496	3692.0
VPS37C	1403	3199.0
VPS4A	-1545	-2729.0
VPS4B	4523	3841.0
VTA1	3283	591.0
XPO1	990	2133.0

---

---

Cytokine Signaling in Immune system

Cytokine Signaling in Immune system

metric	value
setSize	518
pMANOVA	2.97e-12
p.adjustMANOVA	1.31e-10
s.dist	0.182
s.human	-0.0275
s.mouse	0.179
p.human	0.291
p.mouse	4.94e-12

Top 20 genes

Gene	human	mouse
VCL	-4538	5383
FGF7	-5445	4475
ANXA2	-4123	5407
EDA2R	-4901	4493
GDNF	-4043	5263
CSF1	-4242	4888
STAT3	-3885	5276
DUSP2	-4253	4725
RAPGEF1	-3992	4925
MSN	-3907	4981
MAP2K3	-4716	3926
IL4R	-3335	5166
CSK	-3610	4728
NCAM1	-3954	4316
PPIA	-4031	4207
SQSTM1	-3803	4448
TRAF3	-3815	4367
ZEB1	-4223	3785
MET	-3529	4440
TNFRSF1A	-4666	3341

Click HERE to show all gene set members

All member genes

	human	mouse
AAAS	-3476	40
ABCE1	4707	2085
ABHD17A	-1525	-2873
ABHD17B	1639	3541
ABHD17C	-2092	-100
ACTN2	-3104	-1086
ADAM17	2407	736
ADAR	-3014	581
AIP	-707	-2446
AKT1	-4954	1242
AKT2	-4057	-3488
ANGPT1	-853	-3559
ANXA1	537	4783
ANXA2	-4123	5407
APP	-2792	154
ARAF	-3318	-4240
ARF1	566	3011
ARIH1	4268	3623
ARL2	-4142	-2108
ARRB1	-3133	2633
ARRB2	-1089	3740
ATF1	3129	3005
ATF2	3130	2882
B2M	-731	-1801
BCL2	-4633	-3007
BCL2L1	-5181	430
BCL6	-5018	1298
BIRC2	3739	-1431
BIRC3	-4741	1787
BRAF	4103	3023
BRAP	4689	4314
BRWD1	2271	1847
BTRC	-1187	-2761
CALM1	-4464	1071
CAMK2A	-5527	-3819
CAMK2B	-5497	-2856
CAMK2D	-2223	5094
CAMK2G	-2097	-4184
CANX	-836	4822
CASP1	-1298	1115
CASP3	423	5421
CBL	1736	1563
CCL2	2620	5213
CCND1	757	1643
CD36	-582	-4709
CD44	837	5375
CDC42	3308	965
CDKN1A	-4927	3046
CFL1	-909	5151
CHUK	216	3591
CLCF1	-2419	3988
CNKSR1	-2870	3515
CNN2	-4870	2217
COL1A2	-1712	1529
CREB1	2179	-1920
CRK	2145	4206
CRKL	-91	5262
CRLF1	42	531
CSF1	-4242	4888
CSK	-3610	4728
CTF1	-3242	-4939
CUL1	-3121	-833
CUL3	2833	3311
DAB2IP	-5036	2828
DDX58	1593	809
DLG1	-52	2473
DLG3	-1567	-728
DLG4	-1594	1830
DUSP1	-219	1965
DUSP10	-5329	1869
DUSP16	3082	3867
DUSP2	-4253	4725
DUSP3	-5149	-4856
DUSP4	-3613	786
DUSP5	4084	5436
DUSP6	-528	-3212
DUSP7	-3477	-3896
DUSP8	1715	4441
EDA	-124	4230
EDA2R	-4901	4493
EGF	-4568	-4926
EGFR	424	2978
EGR1	4164	4986
EIF2AK2	-486	-129
EIF4A1	2916	5463
EIF4A2	1360	849
EIF4A3	4491	2615
EIF4E	2892	2481
EIF4E2	-2440	724
EIF4E3	-2251	797
EIF4G1	-2988	-962
EIF4G2	1963	3349
EIF4G3	-2799	-188
ELK1	-3862	1269
ERBB2	-5511	494
ERBB3	-5290	-2307
F13A1	-2059	4132
FBXW11	4385	5178
FGF1	798	5410
FGF2	751	3502
FGF7	-5445	4475
FGF9	-5320	-1375
FGFR1	-1499	-1279
FGFR3	3759	4811
FGFR4	-5312	-991
FLNA	-3248	4449
FLNB	2772	2143
FN1	35	4381
FNTA	1578	-3409
FNTB	-690	3507
FOS	1865	5350
FOXO1	-432	3792
FOXO3	-42	2244
FRS2	4678	3571
FRS3	1398	1630
FSCN1	1705	-2925
FYN	-2850	4537
GAB1	-1853	-1642
GAB2	4053	2415
GBP6	-2110	-3690
GDNF	-4043	5263
GFRA1	-4438	-426
GHR	3997	-4315
GOLGA7	1185	2154
GRB2	-4050	3027
GSTO1	-2055	-3769
HBEGF	3484	5518
HIF1A	-1016	5349
HMGB1	-2199	-3939
HMOX1	-2843	4573
HNRNPA2B1	3693	-4286
HNRNPF	4978	3406
HRAS	-4545	-4872
HSP90AA1	3656	5525
HSP90B1	460	4768
HSPA8	3674	5419
HSPA9	2342	-3484
ICAM1	1056	41
ICMT	-2315	2796
IFI27	-1101	-134
IFI35	-3310	-509
IFIT2	-1338	640
IFIT3	-792	-918
IFITM1	1574	4937
IFITM2	-316	4937
IFITM3	380	4937
IFNAR1	3645	1778
IFNAR2	-1316	1704
IFNGR1	2506	1520
IFNGR2	-386	-3292
IKBKB	-4093	2980
IL10RB	1239	2957
IL11RA	-5610	-2130
IL13RA1	-1847	4373
IL15	-2409	-4017
IL16	-1613	-1580
IL17RA	219	5136
IL17RC	-4271	962
IL17RD	-3179	1019
IL17RE	-1865	-3165
IL18BP	292	-52
IL1R1	-3018	4729
IL1RAP	627	4100
IL20RB	-159	844
IL2RG	-1943	582
IL33	1864	3634
IL34	3060	-245
IL4R	-3335	5166
IL6R	-5515	2529
IL6ST	3055	1967
INPP5D	-2433	4627
INPPL1	-5220	-2663
IP6K2	3404	-226
IQGAP1	-415	4295
IRAK1	-4351	-1420
IRAK2	-4255	3504
IRAK3	95	1205
IRAK4	-569	3445
IRF1	-1565	-1908
IRF2	-3387	-1585
IRF3	-3061	-2463
IRF4	-1166	4447
IRF7	775	2624
IRF9	1267	-1738
IRS1	-5550	-3910
IRS2	3384	2249
ISG15	-3928	-331
ITGAM	-2633	5000
ITGAX	-896	-49
ITGB1	956	5174
ITGB2	-107	4082
ITGB3	-488	5180
JAK1	-1869	4962
JAK2	-2569	-2171
JUN	2469	5472
JUNB	-2593	4931
KBTBD7	1566	3776
KITLG	4898	-361
KPNA1	1833	4786
KPNA2	5007	4653
KPNA3	-2337	-979
KPNA4	1501	5379
KPNB1	3619	4744
KRAS	3546	5146
KSR1	-5578	-1928
LAMA5	-5584	-201
LAMTOR2	-1715	-4532
LAMTOR3	3134	781
LIFR	-994	-4778
LMNB1	3392	648
LTBR	-4989	707
LYN	785	2842
LYPLA1	1177	-3204
MAOA	-96	3828
MAP2K1	-506	-3734
MAP2K2	-3813	-2235
MAP2K3	-4716	3926
MAP2K4	8	1873
MAP2K6	1456	-4331
MAP2K7	794	-4191
MAP3K11	-3624	2252
MAP3K3	2825	2589
MAP3K7	2142	1585
MAP3K8	344	1263
MAPK1	1988	-969
MAPK10	-3504	-1276
MAPK11	-3385	1370
MAPK12	-5264	99
MAPK14	-1562	-2824
MAPK3	-1024	4464
MAPK7	-729	2102
MAPK8	457	1743
MAPK9	-3854	-738
MAPKAPK2	-2489	-1825
MAPKAPK3	-4795	1592
MARK3	3178	989
MCL1	2837	5057
MEF2A	-5175	-1587
MEF2C	-4610	2307
MET	-3529	4440
MID1	-4726	-13
MIF	-2307	-3224
MMP2	-692	-606
MRAS	-5239	525
MSN	-3907	4981
MTAP	-2515	2769
MX1	-1867	3839
MYC	3994	185
MYD88	2726	2870
NCAM1	-3954	4316
NDC1	1273	-322
NDN	1146	1941
NEDD4	4583	-2859
NF1	3095	3040
NFKB1	-4233	2228
NFKB2	-3926	2289
NFKBIA	-4263	1229
NFKBIB	4450	2806
NKIRAS1	4369	-4175
NKIRAS2	-1369	665
NOD1	-3886	-667
NOD2	-4402	2741
NRAS	4354	1003
NUP107	3232	3195
NUP133	889	-2580
NUP153	4762	4031
NUP155	4306	2897
NUP160	3998	2314
NUP188	2117	4593
NUP205	4438	3917
NUP214	3124	1845
NUP35	4571	2515
NUP37	-327	-873
NUP43	4562	193
NUP54	4508	4751
NUP85	3181	227
NUP88	1244	1407
NUP93	-1503	5229
NUP98	4235	5486
OAS2	212	2134
OSMR	255	5081
P4HB	-2525	5054
PAK2	1525	5331
PAQR3	396	3145
PDCD4	2217	1970
PDE12	4844	4427
PDE6D	-2753	649
PDGFA	-4328	-2495
PDGFB	-606	1041
PDGFRA	2727	1223
PDGFRB	-2260	2970
PDPK1	3443	3947
PEA15	-1982	1535
PEBP1	-3678	-3474
PELI1	4489	5252
PELI2	3371	1384
PELI3	-4396	2800
PHB	-586	-3838
PIAS1	57	627
PIK3C3	3439	-1596
PIK3CA	365	4218
PIK3CB	2760	5125
PIK3CD	-4322	-2306
PIK3R1	2896	-813
PIK3R3	3188	3545
PIK3R4	3839	-3124
PIM1	-228	1633
PIN1	-3515	-3234
PITPNA	-2450	-1450
PLCG1	-3955	-1787
PML	3338	3242
POU2F1	3019	-1366
PPIA	-4031	4207
PPM1B	4912	2379
PPP1CB	-1374	-3335
PPP1CC	4081	-1627
PPP2CA	4482	1672
PPP2CB	2458	2352
PPP2R1A	-4013	-681
PPP2R1B	3028	3194
PPP2R5A	4590	3889
PPP2R5B	-1524	-765
PPP2R5C	-2508	-293
PPP2R5D	-3449	-620
PPP2R5E	4644	2107
PPP5C	-4582	-3591
PRKACA	-4691	-4303
PRKCD	-4276	1141
PRKCQ	-5095	-4724
PSMA1	2820	4043
PSMA3	3434	-1035
PSMA4	769	-1962
PSMA6	2199	-1657
PSMA7	-2980	-1038
PSMB1	954	-1037
PSMB10	-1800	-831
PSMB2	618	-67
PSMB4	-235	-559
PSMB5	-4113	-2597
PSMB6	-793	-1795
PSMB7	-831	-2699
PSMB8	-675	-2510
PSMB9	-1611	-3558
PSMC1	449	1146
PSMC2	-1311	3386
PSMC3	-2439	-1846
PSMC4	2724	-205
PSMC5	1212	-1680
PSMC6	-2520	3114
PSMD1	2619	3210
PSMD10	-1227	361
PSMD11	995	5504
PSMD12	3831	-462
PSMD13	821	532
PSMD14	-635	3746
PSMD2	-713	741
PSMD3	-3343	-354
PSMD4	-214	968
PSMD5	1807	4479
PSMD6	3537	-3784
PSMD7	-2329	410
PSMD8	-3171	4292
PSMD9	4204	-3586
PSME1	-2771	-2861
PSME2	-4085	-41
PSME3	3333	491
PSME4	1960	2319
PSMF1	683	-1768
PTK2	-2497	2145
PTK2B	-2461	2430
PTPN1	1531	4935
PTPN11	-1575	3105
PTPN12	4141	5222
PTPN13	4200	1720
PTPN14	1287	-1576
PTPN18	-4024	2162
PTPN2	4314	5012
PTPN23	1152	5190
PTPN3	2224	-5017
PTPN4	-1408	5055
PTPN6	-931	4180
PTPN9	-1215	3574
PTPRA	-402	3484
RAE1	4471	3078
RAF1	1712	-1201
RALA	-1368	-1154
RALGDS	-5190	2802
RANBP2	4470	-562
RANBP9	4005	2691
RAP1A	-689	3944
RAP1B	4479	5079
RAPGEF1	-3992	4925
RAPGEF2	4504	-1660
RASA1	-612	2537
RASA2	3565	2417
RASA3	-4990	-58
RASAL2	3510	686
RASGRF2	4373	-3126
RASGRP3	-4774	-4929
RBX1	-733	-2400
RCE1	2361	2291
RELA	1783	4454
RELB	-2305	2910
RGL1	-161	-624
RGL2	-4344	-4226
RHOU	-4229	-3685
RIPK2	3609	4684
RNASEL	2906	-20
RORA	-5056	2669
RORC	-5248	-3275
RPS27A	783	-2165
RPS6KA1	-1481	-1813
RPS6KA2	-4748	-4135
RPS6KA3	952	2296
RPS6KA5	51	-4805
S1PR1	2689	-1019
SAMHD1	48	-2043
SDC1	-2046	1023
SEC13	730	938
SEH1L	1085	4110
SH2B1	-3841	1127
SHC1	3976	4815
SHC2	-3710	3451
SHOC2	4514	3567
SIGIRR	-452	-2169
SKP1	2028	-1286
SMAD3	-3794	-3710
SMARCA4	-3874	863
SNRPA1	4117	3762
SOCS1	199	3983
SOCS3	-283	4943
SOCS5	4145	2774
SOD1	157	-2728
SOD2	-1568	-4837
SOS1	-1962	2326
SOS2	-563	-2646
SPRED1	3312	4628
SPRED2	1200	-1956
SPRED3	-2447	-207
SPTAN1	-2425	412
SPTB	-5499	1118
SPTBN1	-2919	-1221
SQSTM1	-3803	4448
SRC	-3910	3763
STAT1	236	-3457
STAT2	-2601	-1249
STAT3	-3885	5276
STAT5A	-4125	-4449
STAT5B	-5022	-3552
STAT6	-5317	-88
STX1A	-411	1598
STX3	4376	419
STX4	-2347	-2961
SUMO1	4213	-262
SYNGAP1	-3658	2878
TAB1	-4874	-4377
TAB2	2791	3798
TAB3	2116	5258
TALDO1	-2080	-2543
TBK1	673	2827
TCP1	4480	394
TEC	3728	3350
TEK	3580	-1484
TGFB1	-3111	4516
THEM4	-3616	-2987
TIMP1	-1317	5467
TLN1	-3918	3071
TNFRSF12A	1487	5373
TNFRSF14	-3195	155
TNFRSF1A	-4666	3341
TNFRSF1B	-874	4531
TNFRSF25	-3839	-1985
TNFSF12	-5179	-4391
TNIP2	-1370	4330
TOLLIP	-256	1819
TP53	575	3128
TPR	2984	275
TRAF2	-1546	2643
TRAF3	-3815	4367
TRAF6	3468	4662
TRIB3	-1004	2359
TRIM2	28	2380
TRIM21	2960	-2527
TRIM25	-3243	-1502
TRIM26	2745	2403
TRIM3	-1373	4302
TRIM35	3906	-2316
TRIM45	-2733	4675
TRIM5	1812	-4962
TRIM62	-4984	1637
TRIM68	3519	-5044
TRIM8	-5354	1324
TWIST1	2624	1741
TXLNA	-3216	3117
TYK2	-3123	725
UBA3	3512	3512
UBA7	-1671	-2885
UBC	2672	3877
UBE2E1	-1132	-881
UBE2L6	-3548	3305
UBE2M	1247	-854
UBE2N	2545	4245
USP18	45	-3032
VAMP2	-3293	-1899
VAMP7	2376	846
VCAM1	2866	4602
VCL	-4538	5383
VEGFA	-4571	-5070
VIM	-3027	5076
VRK3	464	3294
VWF	-779	1730
WDR83	1010	-3938
XAF1	-320	-184
YES1	-176	-836
YWHAB	3680	3468
YWHAZ	2019	4919
ZDHHC9	-3396	2752
ZEB1	-4223	3785

---

---

rRNA processing

rRNA processing

metric	value
setSize	154
pMANOVA	4.37e-12
p.adjustMANOVA	1.86e-10
s.dist	0.342
s.human	0.338
s.mouse	0.051
p.human	4.82e-13
p.mouse	0.276

Top 20 genes

Gene	human	mouse
DDX21	4868	5307.0
HEATR1	4911	5214.0
UTP14A	4777	5328.5
WDR43	4883	4985.0
DCAF13	4800	4904.0
WDR3	4838	4572.0
NOP58	4891	3903.0
NOL6	3819	4849.0
FTSJ3	4444	4129.0
EXOSC10	4991	3582.0
LTV1	4806	3706.0
NOP2	3472	5052.0
GAR1	4132	4232.0
GNL3	4434	3896.0
ISG20L2	3385	4842.0
TSR1	3117	5039.0
NCL	3573	4049.0
WDR75	3743	3744.0
DIS3	4973	2795.0
XRN2	4296	3178.0

Click HERE to show all gene set members

All member genes

	human	mouse
BMS1	3511	-3149.0
BYSL	2701	1718.0
C1D	3347	-1555.0
CSNK1D	-3539	4717.0
CSNK1E	-5045	3424.0
DCAF13	4800	4904.0
DDX21	4868	5307.0
DDX47	3735	-2506.0
DDX49	2178	4308.0
DHX37	2105	3594.0
DIEXF	4877	-510.0
DIMT1	2537	42.0
DIS3	4973	2795.0
DKC1	3629	1648.0
EBNA1BP2	4030	-1624.0
ELAC2	1520	1770.0
ERI1	2910	2565.0
EXOSC1	1073	3516.0
EXOSC10	4991	3582.0
EXOSC2	3309	2709.0
EXOSC3	3331	784.0
EXOSC4	2447	-3953.0
EXOSC5	20	-4477.0
EXOSC7	-4980	-1705.0
EXOSC8	3102	1509.0
EXOSC9	4106	-1160.0
FAU	2272	2649.0
FBL	4233	-132.0
FCF1	3303	1429.0
FTSJ3	4444	4129.0
GAR1	4132	4232.0
GNL3	4434	3896.0
HEATR1	4911	5214.0
HSD17B10	-1193	-1970.0
IMP3	4536	-4210.0
IMP4	2805	4037.0
ISG20L2	3385	4842.0
KRR1	3921	-1381.0
LAS1L	3707	-585.0
LTV1	4806	3706.0
MPHOSPH10	3928	2821.0
MPHOSPH6	2298	-1743.0
MT-CO1	-3167	-4401.0
MT-CYB	-1355	-4115.0
MT-ND1	-353	-4097.0
MT-ND2	-1120	-4098.0
MT-ND4	-2086	-3521.0
MT-ND5	-3244	-3936.0
NAT10	3642	2679.0
NCL	3573	4049.0
NHP2	694	1773.0
NIP7	3751	2356.0
NOB1	3229	2731.0
NOC4L	1763	-2682.0
NOL11	4916	1935.0
NOL6	3819	4849.0
NOL9	4679	688.0
NOP10	1336	-894.0
NOP14	1590	4297.0
NOP2	3472	5052.0
NOP56	3099	3605.0
NOP58	4891	3903.0
NSUN4	-830	-4482.0
PDCD11	-1465	862.0
PELP1	2605	1451.0
PES1	4214	1923.0
PNO1	4623	-406.0
PWP2	2462	1711.0
RBM28	4327	-99.0
RCL1	3257	237.0
RIOK1	3760	-572.0
RIOK3	-1480	1085.0
RPL10	-3902	3923.0
RPL11	-2249	-1971.0
RPL14	433	-875.0
RPL18	-1782	448.0
RPL18A	-2969	-320.0
RPL19	-502	-1379.0
RPL22	1231	-3446.0
RPL22L1	3380	2374.0
RPL23	-115	-2882.0
RPL26	1047	696.0
RPL28	-391	-1891.0
RPL3	-786	5412.0
RPL30	286	-3056.0
RPL31	-595	2894.0
RPL32	-367	-950.0
RPL34	1447	-1314.0
RPL35A	812	-1471.0
RPL36A	1261	-1408.0
RPL37	-715	-1311.0
RPL37A	-1043	554.0
RPL38	231	-953.0
RPL3L	-5212	-4614.0
RPL4	-522	-571.0
RPL5	1206	3360.0
RPL7	1440	-1894.0
RPL8	-2775	-928.0
RPLP2	-2469	-3389.0
RPP14	2370	-2951.0
RPP30	2968	1603.0
RPP38	3980	480.0
RPP40	3369	-2381.0
RPS11	-1582	-458.0
RPS12	-318	1501.0
RPS13	1131	-1994.0
RPS14	-1412	122.0
RPS15	-1799	-1082.0
RPS15A	-704	-237.0
RPS16	-1828	2010.0
RPS18	-974	-1404.0
RPS19	-2045	-882.0
RPS20	-1844	1712.0
RPS21	-1536	-2810.0
RPS23	-68	-749.0
RPS24	256	-1505.0
RPS26	-282	-1421.0
RPS27A	783	-2165.0
RPS27L	-616	-69.0
RPS29	-1140	-1275.0
RPS3	-544	116.0
RPS4X	83	97.0
RPS5	-1577	935.0
RPS6	-245	1237.0
RPS8	-1593	-1231.0
RPS9	-1107	-2477.0
RRP1	1063	-4885.0
RRP36	1532	29.0
RRP7A	2138	4236.0
RRP9	771	1609.0
SENP3	2112	2776.0
TBL3	-1551	3495.0
TEX10	2840	3253.0
TFB1M	1537	-2725.0
THUMPD1	4666	-558.0
TRMT10C	4780	1827.0
TSR1	3117	5039.0
TSR3	-3611	-4069.0
UTP14A	4777	5328.5
UTP14C	1565	5328.5
UTP15	4137	-396.0
UTP18	3851	2069.0
UTP20	4174	832.0
UTP3	4917	2335.0
UTP6	4779	-1773.0
WBSCR22	1741	-4222.0
WDR12	1739	-1129.0
WDR18	-812	-3151.0
WDR3	4838	4572.0
WDR36	4542	2424.0
WDR43	4883	4985.0
WDR46	3335	3009.0
WDR75	3743	3744.0
XRN2	4296	3178.0

---

---

Major pathway of rRNA processing in the nucleolus and cytosol

Major pathway of rRNA processing in the nucleolus and cytosol

metric	value
setSize	134
pMANOVA	6.73e-12
p.adjustMANOVA	2.77e-10
s.dist	0.37
s.human	0.358
s.mouse	0.0927
p.human	8.79e-13
p.mouse	0.0647

Top 20 genes

Gene	human	mouse
DDX21	4868	5307.0
HEATR1	4911	5214.0
UTP14A	4777	5328.5
WDR43	4883	4985.0
DCAF13	4800	4904.0
WDR3	4838	4572.0
NOP58	4891	3903.0
NOL6	3819	4849.0
FTSJ3	4444	4129.0
EXOSC10	4991	3582.0
LTV1	4806	3706.0
GNL3	4434	3896.0
ISG20L2	3385	4842.0
TSR1	3117	5039.0
NCL	3573	4049.0
WDR75	3743	3744.0
DIS3	4973	2795.0
XRN2	4296	3178.0
UTP3	4917	2335.0
IMP4	2805	4037.0

Click HERE to show all gene set members

All member genes

	human	mouse
BMS1	3511	-3149.0
BYSL	2701	1718.0
C1D	3347	-1555.0
CSNK1D	-3539	4717.0
CSNK1E	-5045	3424.0
DCAF13	4800	4904.0
DDX21	4868	5307.0
DDX47	3735	-2506.0
DDX49	2178	4308.0
DHX37	2105	3594.0
DIEXF	4877	-510.0
DIS3	4973	2795.0
EBNA1BP2	4030	-1624.0
ERI1	2910	2565.0
EXOSC1	1073	3516.0
EXOSC10	4991	3582.0
EXOSC2	3309	2709.0
EXOSC3	3331	784.0
EXOSC4	2447	-3953.0
EXOSC5	20	-4477.0
EXOSC7	-4980	-1705.0
EXOSC8	3102	1509.0
EXOSC9	4106	-1160.0
FAU	2272	2649.0
FBL	4233	-132.0
FCF1	3303	1429.0
FTSJ3	4444	4129.0
GNL3	4434	3896.0
HEATR1	4911	5214.0
IMP3	4536	-4210.0
IMP4	2805	4037.0
ISG20L2	3385	4842.0
KRR1	3921	-1381.0
LAS1L	3707	-585.0
LTV1	4806	3706.0
MPHOSPH10	3928	2821.0
MPHOSPH6	2298	-1743.0
NCL	3573	4049.0
NIP7	3751	2356.0
NOB1	3229	2731.0
NOC4L	1763	-2682.0
NOL11	4916	1935.0
NOL6	3819	4849.0
NOL9	4679	688.0
NOP14	1590	4297.0
NOP56	3099	3605.0
NOP58	4891	3903.0
PDCD11	-1465	862.0
PELP1	2605	1451.0
PES1	4214	1923.0
PNO1	4623	-406.0
PWP2	2462	1711.0
RBM28	4327	-99.0
RCL1	3257	237.0
RIOK1	3760	-572.0
RIOK3	-1480	1085.0
RPL10	-3902	3923.0
RPL11	-2249	-1971.0
RPL14	433	-875.0
RPL18	-1782	448.0
RPL18A	-2969	-320.0
RPL19	-502	-1379.0
RPL22	1231	-3446.0
RPL22L1	3380	2374.0
RPL23	-115	-2882.0
RPL26	1047	696.0
RPL28	-391	-1891.0
RPL3	-786	5412.0
RPL30	286	-3056.0
RPL31	-595	2894.0
RPL32	-367	-950.0
RPL34	1447	-1314.0
RPL35A	812	-1471.0
RPL36A	1261	-1408.0
RPL37	-715	-1311.0
RPL37A	-1043	554.0
RPL38	231	-953.0
RPL3L	-5212	-4614.0
RPL4	-522	-571.0
RPL5	1206	3360.0
RPL7	1440	-1894.0
RPL8	-2775	-928.0
RPLP2	-2469	-3389.0
RPP14	2370	-2951.0
RPP30	2968	1603.0
RPP38	3980	480.0
RPP40	3369	-2381.0
RPS11	-1582	-458.0
RPS12	-318	1501.0
RPS13	1131	-1994.0
RPS14	-1412	122.0
RPS15	-1799	-1082.0
RPS15A	-704	-237.0
RPS16	-1828	2010.0
RPS18	-974	-1404.0
RPS19	-2045	-882.0
RPS20	-1844	1712.0
RPS21	-1536	-2810.0
RPS23	-68	-749.0
RPS24	256	-1505.0
RPS26	-282	-1421.0
RPS27A	783	-2165.0
RPS27L	-616	-69.0
RPS29	-1140	-1275.0
RPS3	-544	116.0
RPS4X	83	97.0
RPS5	-1577	935.0
RPS6	-245	1237.0
RPS8	-1593	-1231.0
RPS9	-1107	-2477.0
RRP1	1063	-4885.0
RRP36	1532	29.0
RRP7A	2138	4236.0
RRP9	771	1609.0
SENP3	2112	2776.0
TBL3	-1551	3495.0
TEX10	2840	3253.0
TSR1	3117	5039.0
UTP14A	4777	5328.5
UTP14C	1565	5328.5
UTP15	4137	-396.0
UTP18	3851	2069.0
UTP20	4174	832.0
UTP3	4917	2335.0
UTP6	4779	-1773.0
WBSCR22	1741	-4222.0
WDR12	1739	-1129.0
WDR18	-812	-3151.0
WDR3	4838	4572.0
WDR36	4542	2424.0
WDR43	4883	4985.0
WDR46	3335	3009.0
WDR75	3743	3744.0
XRN2	4296	3178.0

---

---

Signaling by Rho GTPases

Signaling by Rho GTPases

metric	value
setSize	269
pMANOVA	7.98e-12
p.adjustMANOVA	3.17e-10
s.dist	0.251
s.human	0.00026
s.mouse	0.251
p.human	0.994
p.mouse	1.96e-12

Top 20 genes

Gene	human	mouse
DIAPH2	4914	5143
PKN2	4933	5115
NUP98	4235	5486
RHOB	4609	4443
ROCK1	4876	3865
ARHGAP20	4540	4124
NCKAP1	3563	5090
MAPRE1	3454	5215
PPP2R5A	4590	3889
ACTR2	3547	5008
ARHGEF26	4815	3641
PPP1R12A	4131	4053
RACGAP1	4239	3807
FAM13B	3174	5059
DAAM1	3085	5018
NDEL1	4631	3278
ZWINT	2778	5457
DIAPH1	3282	4405
PDPK1	3443	3947
ARHGEF12	2630	5108

Click HERE to show all gene set members

All member genes

	human	mouse
ABI1	3792	3443
ABI2	-308	5438
ABL1	-4533	1377
ABR	-5353	3387
ACTB	940	5427
ACTG1	-3075	5370
ACTR2	3547	5008
ACTR3	1376	5496
AHCTF1	4662	2760
AKAP13	1322	667
AR	-4468	-4062
ARAP1	-4961	876
ARAP3	-1492	-3743
ARHGAP1	-972	4196
ARHGAP10	-3294	-1719
ARHGAP11B	-4580	3163
ARHGAP12	-3916	-250
ARHGAP17	1457	2720
ARHGAP18	4554	-3352
ARHGAP19	4720	1553
ARHGAP20	4540	4124
ARHGAP21	2554	2948
ARHGAP22	-4747	2007
ARHGAP24	-3475	-798
ARHGAP26	-14	691
ARHGAP27	2783	-910
ARHGAP28	-5091	805
ARHGAP29	4465	-2049
ARHGAP31	-1030	-762
ARHGAP32	-1319	4859
ARHGAP33	-487	1323
ARHGAP35	-4960	5279
ARHGAP39	-3062	2351
ARHGAP4	-3966	4489
ARHGAP42	2893	964
ARHGAP44	686	5224
ARHGAP5	3942	-2428
ARHGAP6	4157	1982
ARHGAP9	-2941	-1677
ARHGDIA	-1439	4781
ARHGEF1	1054	-217
ARHGEF10L	-5596	682
ARHGEF11	-1199	2030
ARHGEF12	2630	5108
ARHGEF17	-5387	85
ARHGEF18	2304	-1935
ARHGEF2	-4945	4225
ARHGEF26	4815	3641
ARHGEF3	-4589	-823
ARHGEF37	-5129	127
ARHGEF4	-3700	211
ARHGEF40	-5458	2410
ARHGEF6	2856	4594
ARHGEF7	-3605	3212
ARHGEF9	-3989	-4009
ARPC1A	-120	2226
ARPC1B	669	4872
ARPC2	1357	2489
ARPC3	2873	1716
ARPC4	1698	-1177
ARPC5	2295	5164
B9D2	1676	-3727
BAIAP2	-641	5424
BCR	4627	2841
BRK1	2026	-636
BUB3	4201	-1316
CALM1	-4464	1071
CDC42	3308	965
CDKN1B	-3284	-2637
CENPC	3555	-133
CENPL	3768	3397
CENPO	1005	3332
CENPQ	1344	5114
CENPT	-2196	4477
CFL1	-909	5151
CHN1	-5262	1681
CHN2	-4930	796
CIT	-2025	2541
CKAP5	-3973	78
CLASP1	-3713	3198
CLASP2	2507	2478
CLIP1	418	-371
CTNNA1	-2198	2829
CTNNB1	1714	2956
CTTN	-4605	5097
CYBA	-633	2247
CYBB	-2550	3868
CYFIP2	-3775	-2981
DAAM1	3085	5018
DEPDC7	3273	2090
DIAPH1	3282	4405
DIAPH2	4914	5143
DLC1	4953	818
DLG4	-1594	1830
DSN1	2075	-665
DVL1	-5428	-3679
DVL2	-2215	-3951
DVL3	-4897	2735
DYNC1H1	-1442	1264
DYNC1I2	2591	172
DYNC1LI1	2883	981
DYNC1LI2	1750	3473
DYNLL1	-1331	3935
EVL	-3566	-1001
FAM13A	4122	-561
FAM13B	3174	5059
FGD1	-3972	3284
FGD3	-3665	3129
FGD4	-4717	-3651
FLNA	-3248	4449
FMNL1	-5159	-64
FMNL2	-650	4673
FMNL3	-1192	2401
GDI1	1662	1387
GDI2	865	4995
GMIP	-2689	3331
GNA13	-209	5323
GOPC	4735	-2584
GRB2	-4050	3027
H2AFX	2356	5181
INCENP	3676	1455
INPP5B	2499	3885
IQGAP1	-415	4295
ITGB1	956	5174
ITGB3BP	1048	-2794
ITSN1	524	-2768
KALRN	-5340	-990
KDM1A	249	5433
KDM4C	814	-807
KIF18A	3832	2448
KIF2A	-4390	4073
KIF5A	4430	584
KIF5B	838	4559
KLC1	-3922	2207
KLC2	-1732	-487
KLC4	-3559	-2759
KTN1	1427	1915
LIMK1	-4857	3467
LIMK2	-5357	-3001
MAD1L1	-3382	1367
MAD2L1	1101	1981
MAPK1	1988	-969
MAPK11	-3385	1370
MAPK14	-1562	-2824
MAPK3	-1024	4464
MAPRE1	3454	5215
MCF2L	-5254	1060
MEN1	1348	426
MIS12	2400	5092
MYH10	50	5272
MYH14	-3853	-3524
MYH9	-1879	4997
MYL12B	1563	594
MYL6	-3628	1353
MYL9	-4777	-1049
MYLK	-3879	1507
MYO9A	3168	3690
MYO9B	-1901	4621
NCK1	3718	2059
NCKAP1	3563	5090
NCKIPSD	-2821	3136
NCOA2	146	558
NDE1	4322	-1640
NDEL1	4631	3278
NET1	-5146	2540
NF2	-1449	-3031
NUDC	3212	-860
NUP107	3232	3195
NUP133	889	-2580
NUP160	3998	2314
NUP37	-327	-873
NUP43	4562	193
NUP85	3181	227
NUP98	4235	5486
OBSCN	-5563	-275
OCRL	2293	3260
OPHN1	616	-3566
PAFAH1B1	-2026	1737
PAK1	-5419	-4706
PAK2	1525	5331
PDPK1	3443	3947
PFN1	467	-2704
PFN2	-4209	-2786
PIK3C3	3439	-1596
PIK3R4	3839	-3124
PIN1	-3515	-3234
PKN1	-4379	2357
PKN2	4933	5115
PKN3	-3848	310
PLEKHG2	-708	4175
PLEKHG5	-4706	-2803
PPP1CB	-1374	-3335
PPP1CC	4081	-1627
PPP1R12A	4131	4053
PPP1R12B	-5005	2701
PPP2CA	4482	1672
PPP2CB	2458	2352
PPP2R1A	-4013	-681
PPP2R1B	3028	3194
PPP2R5A	4590	3889
PPP2R5B	-1524	-765
PPP2R5C	-2508	-293
PPP2R5D	-3449	-620
PPP2R5E	4644	2107
PRC1	112	4093
PREX1	188	2037
PRKCA	-2938	1125
PRKCD	-4276	1141
PTK2	-2497	2145
RAC1	2525	-240
RAC2	41	4138
RACGAP1	4239	3807
RALBP1	2524	2961
RANBP2	4470	-562
RANGAP1	483	4468
RASGRF2	4373	-3126
RCC2	4178	3180
RHOA	539	4106
RHOB	4609	4443
RHOBTB1	4915	-1398
RHOBTB2	-3428	-4485
RHOC	-4944	4844
RHOG	-1207	5167
RHOJ	164	1325
RHOQ	-1357	-1546
RHOT1	-3626	-2070
RHOT2	-5266	-4422
RHOU	-4229	-3685
RHPN2	3217	517
ROCK1	4876	3865
ROCK2	2205	1929
RTKN	-5092	-1124
SCAI	-726	-536
SEC13	730	938
SEH1L	1085	4110
SKA2	2399	946
SOS1	-1962	2326
SOS2	-563	-2646
SRC	-3910	3763
SRF	-4281	3531
SRGAP1	938	2617
SRGAP3	-3043	3924
STARD13	-4235	4774
STARD8	-2599	3031
SYDE1	-968	1574
SYDE2	-263	-1014
TAOK1	1644	130
TAX1BP3	-710	3864
TIAM1	2024	-347
TIAM2	-3379	5429
TRIO	1163	-378
TRIP10	-4547	-4755
VAV2	-4959	2847
VAV3	187	-276
WASF2	-4656	3026
WASF3	-1015	1293
WASL	2683	4511
WIPF1	-2552	2457
WIPF2	3299	-608
WIPF3	-5107	-4936
XPO1	990	2133
YWHAB	3680	3468
YWHAE	1394	-2051
YWHAG	-2372	1012
YWHAH	-2777	3808
YWHAQ	963	3949
YWHAZ	2019	4919
ZW10	1474	3364
ZWINT	2778	5457

---

---

Transport of Mature mRNA derived from an Intron-Containing Transcript

Transport of Mature mRNA derived from an Intron-Containing Transcript

metric	value
setSize	60
pMANOVA	1.03e-11
p.adjustMANOVA	3.97e-10
s.dist	0.556
s.human	0.52
s.mouse	0.197
p.human	3.24e-12
p.mouse	0.00832

Top 20 genes

Gene	human	mouse
NUP98	4235	5486
CDC40	4670	4950
ALYREF	5008	4414
NUP54	4508	4751
NUP153	4762	4031
NUP205	4438	3917
FYTTD1	3374	4804
RAE1	4471	3078
U2AF2	4337	2964
NUP155	4306	2897
EIF4A3	4491	2615
SLU7	4893	2372
NUP35	4571	2515
NUP107	3232	3195
NUP188	2117	4593
SRSF9	3543	2675
NUP160	3998	2314
THOC1	2868	2971
SRSF7	3545	2132
SRSF4	1929	3741

Click HERE to show all gene set members

All member genes

	human	mouse
AAAS	-3476	40
ALYREF	5008	4414
CASC3	9	2673
CDC40	4670	4950
CHTOP	-574	2577
DDX39A	3417	-377
DDX39B	984	839
DHX38	2857	440
EIF4A3	4491	2615
FYTTD1	3374	4804
GLE1	586	-1322
MAGOH	4561	555
MAGOHB	2239	-1880
NCBP1	-1736	4720
NCBP2	4188	-2519
NDC1	1273	-322
NUP107	3232	3195
NUP133	889	-2580
NUP153	4762	4031
NUP155	4306	2897
NUP160	3998	2314
NUP188	2117	4593
NUP205	4438	3917
NUP214	3124	1845
NUP35	4571	2515
NUP37	-327	-873
NUP43	4562	193
NUP54	4508	4751
NUP85	3181	227
NUP88	1244	1407
NUP93	-1503	5229
NUP98	4235	5486
NXF1	4992	-1556
NXT1	1765	3075
POLDIP3	-1320	5061
RAE1	4471	3078
RANBP2	4470	-562
RNPS1	681	-2204
SARNP	569	-1380
SEC13	730	938
SEH1L	1085	4110
SLU7	4893	2372
SRRM1	2285	-2017
SRSF1	1871	-1493
SRSF11	3911	-1990
SRSF3	2586	1697
SRSF4	1929	3741
SRSF5	1997	-3060
SRSF6	1798	2387
SRSF7	3545	2132
SRSF9	3543	2675
THOC1	2868	2971
THOC2	4510	561
THOC3	2831	-3387
THOC5	4842	-589
THOC6	-904	2005
THOC7	-873	-3232
TPR	2984	275
U2AF2	4337	2964
UPF3B	1586	-4490

---

---

Transport of Mature Transcript to Cytoplasm

Transport of Mature Transcript to Cytoplasm

metric	value
setSize	69
pMANOVA	1.06e-11
p.adjustMANOVA	3.97e-10
s.dist	0.522
s.human	0.48
s.mouse	0.204
p.human	5.44e-12
p.mouse	0.00345

Top 20 genes

Gene	human	mouse
NUP98	4235	5486
CDC40	4670	4950
ALYREF	5008	4414
NUP54	4508	4751
NUP153	4762	4031
NUP205	4438	3917
FYTTD1	3374	4804
RAE1	4471	3078
U2AF2	4337	2964
NUP155	4306	2897
SLBP	2666	4469
EIF4A3	4491	2615
SLU7	4893	2372
NUP35	4571	2515
FIP1L1	3587	3058
NUP107	3232	3195
NUP188	2117	4593
SRSF9	3543	2675
NUP160	3998	2314
THOC1	2868	2971

Click HERE to show all gene set members

All member genes

	human	mouse
AAAS	-3476	40
ALYREF	5008	4414
CASC3	9	2673
CDC40	4670	4950
CHTOP	-574	2577
CPSF1	-3670	977
CPSF2	-922	-1111
CPSF3	1953	2237
CPSF4	862	4202
DDX39A	3417	-377
DDX39B	984	839
DHX38	2857	440
EIF4A3	4491	2615
EIF4E	2892	2481
FIP1L1	3587	3058
FYTTD1	3374	4804
GLE1	586	-1322
MAGOH	4561	555
MAGOHB	2239	-1880
NCBP1	-1736	4720
NCBP2	4188	-2519
NDC1	1273	-322
NUP107	3232	3195
NUP133	889	-2580
NUP153	4762	4031
NUP155	4306	2897
NUP160	3998	2314
NUP188	2117	4593
NUP205	4438	3917
NUP214	3124	1845
NUP35	4571	2515
NUP37	-327	-873
NUP43	4562	193
NUP54	4508	4751
NUP85	3181	227
NUP88	1244	1407
NUP93	-1503	5229
NUP98	4235	5486
NXF1	4992	-1556
NXT1	1765	3075
POLDIP3	-1320	5061
RAE1	4471	3078
RANBP2	4470	-562
RNPS1	681	-2204
SARNP	569	-1380
SEC13	730	938
SEH1L	1085	4110
SLBP	2666	4469
SLU7	4893	2372
SRRM1	2285	-2017
SRSF1	1871	-1493
SRSF11	3911	-1990
SRSF3	2586	1697
SRSF4	1929	3741
SRSF5	1997	-3060
SRSF6	1798	2387
SRSF7	3545	2132
SRSF9	3543	2675
SYMPK	-3207	-1626
THOC1	2868	2971
THOC2	4510	561
THOC3	2831	-3387
THOC5	4842	-589
THOC6	-904	2005
THOC7	-873	-3232
TPR	2984	275
U2AF2	4337	2964
UPF3B	1586	-4490
WDR33	3143	-994

---

---

Signaling by Receptor Tyrosine Kinases

Signaling by Receptor Tyrosine Kinases

metric	value
setSize	357
pMANOVA	1.47e-11
p.adjustMANOVA	5.32e-10
s.dist	0.208
s.human	-0.0462
s.mouse	0.203
p.human	0.137
p.mouse	6.49e-11

Top 20 genes

Gene	human	mouse
TNS3	-5416	5176
HSPB1	-4869	5539
BCAR1	-4922	5371
FGF7	-5445	4475
FOSL1	-4491	5244
NAB2	-5323	4380
RANBP10	-4779	4540
FOSB	-4733	4375
FURIN	-4221	4897
STAT3	-3885	5276
SH2B3	-4833	4233
RAPGEF1	-3992	4925
EGR2	-3746	5163
AXL	-4171	4393
FLRT2	-4342	4178
CSK	-3610	4728
EGR3	-3215	5298
TCIRG1	-3600	4574
CXCL12	-4998	3271
MET	-3529	4440

Click HERE to show all gene set members

All member genes

	human	mouse
AAMP	2657	2106
ABI1	3792	3443
ABI2	-308	5438
ADAM10	-1509	1096
ADAM12	652	5402
ADAM17	2407	736
AHCYL1	-3386	2570
AKT1	-4954	1242
AKT2	-4057	-3488
AKT3	1343	2419
AP2A1	-3632	-3002
AP2A2	-1058	5459
AP2B1	-1157	4733
AP2M1	-2746	1678
AP2S1	1777	-582
APH1A	204	-3096
APH1B	3428	1940
APOE	-1428	-1396
ARC	4190	3458
ARF6	3503	4901
ARHGEF7	-3605	3212
ATF1	3129	3005
ATF2	3130	2882
ATP6AP1	-342	-3461
ATP6V0A1	-3809	3329
ATP6V0A2	186	-1285
ATP6V0B	-3461	-2887
ATP6V0D1	-2256	2038
ATP6V0E1	1861	1404
ATP6V0E2	-1727	-2450
ATP6V1A	1633	2509
ATP6V1B2	2299	4785
ATP6V1C1	3521	4933
ATP6V1D	3269	-4077
ATP6V1E1	3913	495
ATP6V1F	-3562	-1774
ATP6V1G2	1570	144
ATP6V1H	-57	1416
AXL	-4171	4393
BAIAP2	-641	5424
BAX	-1846	4611
BCAR1	-4922	5371
BDNF	1086	5317
BRAF	4103	3023
BRK1	2026	-636
CALM1	-4464	1071
CAV1	-646	-1312
CBL	1736	1563
CDC37	-1724	-3392
CDC42	3308	965
CDK5	-1007	-2874
CHD4	-4283	1724
CILP	-417	4667
CLTA	1218	-119
CLTC	2268	2273
COL4A1	-4755	1270
COL4A2	-5035	827
COL4A3	-3831	-4180
COL4A4	-3022	-3438
COL4A5	-4320	-2713
COL6A1	-1945	2783
COL6A2	-1836	2972
COL6A3	-119	3607
COL6A6	-2138	-1882
CREB1	2179	-1920
CRK	2145	4206
CRKL	-91	5262
CSK	-3610	4728
CTNNA1	-2198	2829
CTNNB1	1714	2956
CTNND1	949	4243
CUL5	2599	-2062
CXCL12	-4998	3271
CYBA	-633	2247
CYBB	-2550	3868
CYFIP2	-3775	-2981
DIAPH1	3282	4405
DLG4	-1594	1830
DNAL4	-1632	-1736
DNM1	-747	1423
DNM2	-1149	218
DNM3	4865	1236
DOCK1	-226	2409
DOCK7	4461	2938
DUSP3	-5149	-4856
DUSP4	-3613	786
DUSP6	-528	-3212
DUSP7	-3477	-3896
EGF	-4568	-4926
EGFR	424	2978
EGR1	4164	4986
EGR2	-3746	5163
EGR3	-3215	5298
ELK1	-3862	1269
ELMO1	-2166	2524
ELMO2	-354	1439
EP300	3403	2309
EPN1	-3102	-4701
EPS15	5	-415
EPS15L1	-444	-1146
ERBB2	-5511	494
ERBB3	-5290	-2307
ESR1	-1770	-2342
F3	-1733	2873
FER	1666	4504
FES	559	2496
FGF1	798	5410
FGF2	751	3502
FGF7	-5445	4475
FGF9	-5320	-1375
FGFBP3	3093	192
FGFR1	-1499	-1279
FGFR3	3759	4811
FGFR4	-5312	-991
FGFRL1	218	-514
FLRT2	-4342	4178
FLRT3	4144	4853
FOS	1865	5350
FOSB	-4733	4375
FOSL1	-4491	5244
FRS2	4678	3571
FRS3	1398	1630
FURIN	-4221	4897
FYN	-2850	4537
GAB1	-1853	-1642
GAB2	4053	2415
GGA3	580	3687
GRB10	-1615	3264
GRB2	-4050	3027
GTF2F1	4999	4439
GTF2F2	4067	5047
HBEGF	3484	5518
HGS	2410	5267
HNRNPA1	3878	4262
HNRNPF	4978	3406
HNRNPH1	3339	5250
HNRNPM	4022	-4783
HRAS	-4545	-4872
HSP90AA1	3656	5525
HSPB1	-4869	5539
ID1	-1307	-719
ID2	3773	3303
ID3	-5372	624
ID4	4977	5182
IGF1R	-144	1570
IGF2	-4754	2227
INSR	-2945	-271
IRS1	-5550	-3910
IRS2	3384	2249
ITCH	4319	2263
ITGA3	-5514	2747
ITGAV	-819	2947
ITGB1	956	5174
ITGB3	-488	5180
ITPR1	4903	1106
ITPR2	1242	53
ITPR3	-3631	-2403
JAK2	-2569	-2171
JUNB	-2593	4931
JUND	1410	3318
JUP	1723	4991
KIDINS220	3922	-1933
KITLG	4898	-361
KRAS	3546	5146
LAMA2	-3799	1005
LAMA3	-1011	-1639
LAMA4	746	766
LAMA5	-5584	-201
LAMB1	-457	829
LAMB2	-4894	-176
LAMB3	-4991	-2671
LAMC1	-3224	3688
LAMC2	1351	5422
LAMC3	-1576	-3666
LRIG1	-5443	437
LYN	785	2842
MAP2K1	-506	-3734
MAP2K2	-3813	-2235
MAP2K5	-4711	-2589
MAPK1	1988	-969
MAPK11	-3385	1370
MAPK12	-5264	99
MAPK14	-1562	-2824
MAPK3	-1024	4464
MAPK7	-729	2102
MAPKAP1	-405	1545
MAPKAPK2	-2489	-1825
MAPKAPK3	-4795	1592
MEF2A	-5175	-1587
MEF2C	-4610	2307
MEF2D	-5348	-255
MEMO1	-1214	-328
MET	-3529	4440
MKNK1	-2212	-3230
MLST8	-3485	-1820
MTOR	-1191	583
MXD4	-1008	906
NAB1	-3099	2676
NAB2	-5323	4380
NCBP1	-1736	4720
NCBP2	4188	-2519
NCK1	3718	2059
NCK2	-953	-4234
NCKAP1	3563	5090
NCOR1	2625	-1011
NCSTN	-2504	-846
NEDD4	4583	-2859
NELFB	-1196	2017
NRAS	4354	1003
NRP1	-112	-3592
NRP2	2152	-1368
NTF3	-2996	-2444
NTF4	-3432	-1335
PAG1	-2006	3400
PAK1	-5419	-4706
PAK2	1525	5331
PCSK5	1905	3089
PCSK6	-3791	-944
PDGFA	-4328	-2495
PDGFB	-606	1041
PDGFC	1650	3966
PDGFD	1552	-1845
PDGFRA	2727	1223
PDGFRB	-2260	2970
PDPK1	3443	3947
PGF	-3714	661
PIK3C3	3439	-1596
PIK3CA	365	4218
PIK3CB	2760	5125
PIK3R1	2896	-813
PIK3R3	3188	3545
PIK3R4	3839	-3124
PLAT	1414	4193
PLCG1	-3955	-1787
POLR2A	3861	5366
POLR2B	4509	-3401
POLR2C	4529	-4002
POLR2D	1669	3230
POLR2E	-667	148
POLR2G	89	4349
POLR2H	-3927	2213
POLR2I	-154	-2504
POLR2K	2480	-3599
POLR2L	-4314	-1126
PPP2CA	4482	1672
PPP2CB	2458	2352
PPP2R1A	-4013	-681
PPP2R1B	3028	3194
PPP2R5D	-3449	-620
PRKACA	-4691	-4303
PRKACB	-2659	-360
PRKCA	-2938	1125
PRKCD	-4276	1141
PRKCE	-4307	-348
PRR5	-837	161
PSEN1	2070	3570
PSEN2	-5371	-3111
PSENEN	-2638	-2344
PTBP1	3063	4580
PTK2	-2497	2145
PTK2B	-2461	2430
PTPN1	1531	4935
PTPN11	-1575	3105
PTPN12	4141	5222
PTPN18	-4024	2162
PTPN2	4314	5012
PTPN3	2224	-5017
PTPN6	-931	4180
PTPRJ	391	4189
PTPRK	211	1310
PTPRO	1419	2718
PTPRS	-4613	-4065
PXN	-4750	1059
RAB4A	1790	-3415
RAC1	2525	-240
RALA	-1368	-1154
RALB	-2362	780
RALGDS	-5190	2802
RANBP10	-4779	4540
RANBP9	4005	2691
RAP1A	-689	3944
RAP1B	4479	5079
RAPGEF1	-3992	4925
RASA1	-612	2537
RBFOX2	-4887	-2254
REST	1113	2845
RHOA	539	4106
RICTOR	3562	1082
RIT1	4448	1706
RNF41	1588	4825
ROCK1	4876	3865
ROCK2	2205	1929
RPS27A	783	-2165
RPS6KA1	-1481	-1813
RPS6KA2	-4748	-4135
RPS6KA3	952	2296
RPS6KA5	51	-4805
RRAD	4389	4932
SGK1	1084	-4376
SH2B2	-4553	2511
SH2B3	-4833	4233
SH3GL1	-2937	2600
SH3KBP1	1014	-4274
SHC1	3976	4815
SHC2	-3710	3451
SOCS1	199	3983
SOCS6	-2366	3321
SOS1	-1962	2326
SPARC	-2672	1436
SPHK1	443	3667
SPP1	1162	2350
SPRED1	3312	4628
SPRED2	1200	-1956
SPRY1	4004	-2764
SPRY2	-3817	2177
SRC	-3910	3763
SRF	-4281	3531
STAM	3932	5249
STAM2	3489	4749
STAT1	236	-3457
STAT3	-3885	5276
STAT5A	-4125	-4449
STAT5B	-5022	-3552
STAT6	-5317	-88
STMN1	-959	1185
STUB1	-2898	-3668
TAB2	2791	3798
TCF12	1614	4852
TCIRG1	-3600	4574
TEC	3728	3350
THBS1	762	5034
THBS2	379	1016
THBS3	-4348	2778
THBS4	-280	3054
THEM4	-3616	-2987
TIA1	3336	-1995
TIAL1	1738	-1479
TIAM1	2024	-347
TNS3	-5416	5176
TPH1	-823	-1096
TRIB1	-2384	5069
TRIB3	-1004	2359
UBC	2672	3877
USP8	4301	-947
VAV2	-4959	2847
VAV3	187	-276
VEGFA	-4571	-5070
VEGFB	-4617	-3478
VEGFC	1169	2268
VRK3	464	3294
WASF2	-4656	3026
WASF3	-1015	1293
WWOX	1055	-3485
WWP1	-1200	-3658
YAP1	-476	5038
YES1	-176	-836
YWHAB	3680	3468

---

---

Mitochondrial Fatty Acid Beta-Oxidation

Mitochondrial Fatty Acid Beta-Oxidation

metric	value
setSize	30
pMANOVA	2.13e-11
p.adjustMANOVA	7.5e-10
s.dist	0.783
s.human	-0.336
s.mouse	-0.708
p.human	0.00148
p.mouse	1.94e-11

Top 20 genes

Gene	human	mouse
ACOT11	-5260	-4722.0
ACADVL	-4952	-4770.0
ACAD10	-4565	-4492.0
ACADS	-4663	-4266.0
ECHS1	-3895	-4648.0
ECI1	-3975	-4524.0
ACOT2	-2912	-4940.5
HADHA	-3202	-4418.0
HADH	-2786	-5075.0
ACOT13	-2994	-4635.0
DECR1	-2617	-4927.0
PCCA	-2597	-4409.0
ACAA2	-2330	-4889.0
THEM4	-3616	-2987.0
MECR	-3190	-3135.0
HADHB	-2035	-4747.0
ACADM	-1714	-4943.0
ACADL	-1021	-4991.0
MCEE	-816	-4855.0
MCAT	-628	-4342.0

Click HERE to show all gene set members

All member genes

	human	mouse
ACAA2	-2330	-4889.0
ACAD10	-4565	-4492.0
ACAD11	421	-5042.0
ACADL	-1021	-4991.0
ACADM	-1714	-4943.0
ACADS	-4663	-4266.0
ACADVL	-4952	-4770.0
ACOT1	1587	-4940.5
ACOT11	-5260	-4722.0
ACOT13	-2994	-4635.0
ACOT2	-2912	-4940.5
ACOT7	-716	4137.0
ACOT9	478	5113.0
ACSF2	-5148	1368.0
DBI	-2859	-619.0
DECR1	-2617	-4927.0
ECHS1	-3895	-4648.0
ECI1	-3975	-4524.0
HADH	-2786	-5075.0
HADHA	-3202	-4418.0
HADHB	-2035	-4747.0
MCAT	-628	-4342.0
MCEE	-816	-4855.0
MECR	-3190	-3135.0
MMAA	2798	-4294.0
NDUFAB1	1151	-3286.0
PCCA	-2597	-4409.0
PCCB	-165	-4900.0
PCTP	-322	-3225.0
THEM4	-3616	-2987.0

---

---

RNA Polymerase II Transcription

RNA Polymerase II Transcription

metric	value
setSize	889
pMANOVA	3.86e-11
p.adjustMANOVA	1.32e-09
s.dist	0.146
s.human	0.138
s.mouse	0.0469
p.human	8.38e-12
p.mouse	0.0204

Top 20 genes

Gene	human	mouse
TAF4B	4967	5489
CTR9	4954	5471
CLP1	4787	5453
SUPT6H	4807	5334
TAF7	4717	5281
CDK12	4852	5130
MED13	4601	5355
ELL2	4753	5145
RYBP	4895	4848
GTF2B	4276	5493
EAF1	4531	5165
CDC40	4670	4950
PLK2	4764	4721
NFYA	4965	4520
GTF2F1	4999	4439
RBM14	4731	4683
ALYREF	5008	4414
ZKSCAN5	4612	4666
SIRT1	4935	4355
RNF111	3964	5247

Click HERE to show all gene set members

All member genes

	human	mouse
ABCA6	-135	-3581.0
ABL1	-4533	1377.0
ACTL6A	4077	2128.0
AFF4	3610	4555.0
AGO1	2453	283.0
AGO2	-4001	3296.0
AGO3	2529	188.0
AGO4	-3006	-1611.0
AIFM2	-4217	-3792.0
AKT1	-4954	1242.0
AKT2	-4057	-3488.0
AKT3	1343	2419.0
ALYREF	5008	4414.0
ANAPC1	572	-470.0
ANAPC10	1974	2927.0
ANAPC11	-3265	-2502.0
ANAPC15	-3393	1658.0
ANAPC16	-3612	-3229.0
ANAPC2	-2185	-1142.0
ANAPC4	-720	-3761.0
ANAPC5	1284	-3105.0
ANAPC7	1595	882.0
APAF1	-3469	3979.0
APOE	-1428	-1396.0
AR	-4468	-4062.0
ARID1A	-1226	4164.0
ARID1B	-3838	4159.0
ARID2	2812	1097.0
ARID3A	-4418	2066.0
ASH2L	-45	-4934.0
ASUN	1039	3366.0
ATAD2	4225	2993.0
ATF2	3130	2882.0
ATM	1449	-3358.0
ATP1B4	-5072	3790.0
ATR	1983	1782.0
ATXN3	4003	1979.0
AURKA	3811	-2443.0
AUTS2	-4742	3797.0
AXIN1	-730	3755.0
BANP	2381	4757.0
BAX	-1846	4611.0
BCL2L11	-4974	234.0
BCL6	-5018	1298.0
BDNF	1086	5317.0
BID	-4951	3351.0
BLM	1103	4665.0
BMI1	3349	3812.0
BMP2	-4256	1160.0
BNIP3L	3835	-2712.0
BRD1	-2076	190.0
BRD2	4330	4714.0
BRD7	221	-3080.0
BRPF1	3074	4211.0
BRPF3	3668	4607.0
BTG1	3137	5099.0
BTG2	-5444	5528.0
CALM1	-4464	1071.0
CAMK2A	-5527	-3819.0
CAMK2B	-5497	-2856.0
CAMK2D	-2223	5094.0
CAMK2G	-2097	-4184.0
CARM1	-4331	-1463.0
CASC3	9	2673.0
CASP1	-1298	1115.0
CASP2	2946	-2821.0
CASP6	4829	-2899.0
CAT	-4828	-4447.0
CAV1	-646	-1312.0
CBFB	3786	-2549.0
CBX2	2360	-1727.0
CBX4	3208	4922.0
CBX5	1538	1494.0
CBX6	-482	1921.0
CBX8	-917	-1786.0
CCNA2	3061	2333.0
CCNC	4650	3631.0
CCND1	757	1643.0
CCND2	225	2762.0
CCND3	786	1243.0
CCNE1	4388	4060.0
CCNE2	4667	-521.0
CCNG1	1596	-2539.0
CCNG2	-2635	-1516.0
CCNH	3825	-1939.0
CCNK	3139	-346.0
CCNT1	4896	309.0
CCNT2	4381	-4634.0
CDC16	86	-1235.0
CDC23	3850	1048.0
CDC26	2750	2001.0
CDC27	665	3905.0
CDC40	4670	4950.0
CDC7	2421	3646.0
CDC73	2659	3408.0
CDK1	1580	3204.0
CDK12	4852	5130.0
CDK13	4123	3295.0
CDK2	849	2902.0
CDK4	703	2603.0
CDK5	-1007	-2874.0
CDK6	1090	2660.0
CDK7	1571	326.0
CDK8	623	-1266.0
CDK9	-1348	4755.0
CDKN1A	-4927	3046.0
CDKN1B	-3284	-2637.0
CDKN2B	-2827	-832.0
CEBPB	-4699	-3003.0
CENPJ	1720	200.0
CHD3	-3721	-2281.0
CHD4	-4283	1724.0
CHEK2	1311	-33.0
CHM	1406	544.0
CHTOP	-574	2577.0
CITED2	770	4652.0
CITED4	-4657	-5028.0
CLDN5	-2058	-4160.0
CLP1	4787	5453.0
CNOT1	4456	1508.0
CNOT10	1314	-2583.0
CNOT11	2698	1032.0
CNOT2	3263	518.0
CNOT3	857	2288.0
CNOT4	2350	1422.0
CNOT6	1509	4740.0
CNOT6L	-2201	3671.0
CNOT7	1298	2117.0
CNOT8	3240	-3842.0
COL1A1	-1639	1801.0
COX11	-2860	-2700.0
COX14	-2772	-4676.0
COX16	-2259	-2674.0
COX18	-554	-2459.0
COX19	3053	2889.0
COX20	1104	-3676.0
COX4I1	-2357	-3606.0
COX5A	-2511	-4214.0
COX5B	-2559	-4822.0
COX6A1	2259	-1583.0
COX6B1	-2231	-3407.0
COX6C	-18	-3754.0
COX7B	144	-2853.0
COX7C	-1495	-3356.0
COX8A	-4337	-3691.0
CPSF1	-3670	977.0
CPSF2	-922	-1111.0
CPSF3	1953	2237.0
CPSF3L	-1923	1313.0
CPSF4	862	4202.0
CPSF7	407	-1612.0
CRADD	-2847	-4359.0
CREB1	2179	-1920.0
CREBBP	1506	4134.0
CSNK2A1	1796	-2551.0
CSNK2A2	2123	2667.0
CSNK2B	1917	-1746.0
CSTF1	2216	1705.0
CSTF2	1437	-1058.0
CSTF2T	2703	4379.0
CSTF3	-2793	4119.0
CTDP1	2071	4946.0
CTGF	-275	4418.0
CTNNB1	1714	2956.0
CTR9	4954	5471.0
CTSK	2	2230.0
CTSV	2209	1721.0
CUL1	-3121	-833.0
DAXX	4449	3854.0
DDB2	-5027	-3642.0
DDIT3	-1718	-2205.0
DDIT4	-2764	4387.0
DDX39A	3417	-377.0
DDX39B	984	839.0
DEK	2056	4276.0
DGCR8	-4643	2467.0
DHX38	2857	440.0
DLL1	-3980	-2417.0
DNA2	37	3262.0
DPY30	3923	-1391.0
DYRK2	-2000	-210.0
E2F1	-529	4887.0
E2F4	-439	4952.0
E2F5	-249	1172.0
E2F6	650	-3961.0
E2F7	512	3554.0
E2F8	-5620	3457.0
EAF1	4531	5165.0
EED	3304	3108.0
EGFR	424	2978.0
EHMT1	-76	902.0
EHMT2	-520	-2448.0
EIF4A3	4491	2615.0
ELF1	4399	4183.0
ELF2	-2817	-2633.0
ELL	-3990	3539.0
ELL2	4753	5145.0
EP300	3403	2309.0
EPC1	362	4609.0
ERBB2	-5511	494.0
ERCC2	824	4319.0
ERCC3	473	3200.0
ESR1	-1770	-2342.0
ESRRA	-4570	-4658.0
ESRRB	-2671	2642.0
ESRRG	-4340	-4075.0
EZH2	4698	4282.0
FANCC	-709	-911.0
FAS	-4771	2003.0
FBXO32	-4380	-4503.0
FBXW7	-886	1644.0
FIP1L1	3587	3058.0
FKBP5	750	-1102.0
FOS	1865	5350.0
FOXO1	-432	3792.0
FOXO3	-42	2244.0
FOXO4	-3493	-3713.0
FOXO6	-4157	-792.0
FYTTD1	3374	4804.0
FZR1	-1244	3161.0
G6PD	579	5116.0
GADD45A	514	-1269.0
GAMT	-5400	-2080.0
GATAD2A	-975	5411.0
GATAD2B	304	4882.0
GLI2	-1180	3016.0
GLI3	3731	3520.0
GLS	4937	1394.0
GPAM	1132	-5046.0
GPI	-5210	-4750.0
GPS2	2002	-25.0
GSK3B	897	4692.0
GSR	-2148	848.0
GTF2A1	4730	4204.0
GTF2A2	4648	-2956.0
GTF2B	4276	5493.0
GTF2E1	2188	896.0
GTF2E2	2041	-136.0
GTF2F1	4999	4439.0
GTF2F2	4067	5047.0
GTF2H1	3886	647.0
GTF2H2	4419	-2426.5
GTF2H3	-1925	-664.0
GTF2H5	-878	-3245.0
H2AFX	2356	5181.0
HDAC10	-3116	762.0
HDAC11	-4482	3061.0
HDAC2	4386	-579.0
HDAC3	-178	-2363.0
HDAC4	-5061	-1561.0
HDAC5	-4921	3448.0
HDAC6	-4164	4690.0
HDAC7	-3827	-1671.0
HDAC8	209	-3383.0
HDAC9	-3759	4259.0
HES1	1695	-3299.0
HEY1	4826	210.0
HIPK1	4147	4913.0
HIPK2	-4312	2753.0
HIVEP3	-179	5045.0
HSPD1	-855	-3145.0
HTT	-70	5026.0
HUS1	2435	-1222.0
IGFBP3	2922	-1589.0
ING2	3993	-432.0
ING5	-2726	1628.0
INTS1	-1418	76.0
INTS10	4175	-3657.0
INTS12	3830	3259.0
INTS2	1193	2278.0
INTS3	1102	3704.0
INTS4	1878	1971.0
INTS5	1592	3335.0
INTS6	2200	5171.0
INTS7	2980	-1292.0
INTS8	1194	3742.0
INTS9	1494	3549.0
IRAK1	-4351	-1420.0
ITCH	4319	2263.0
ITGA4	-2878	-2673.0
ITGA5	-4752	5495.0
ITGBL1	1885	986.0
IWS1	2510	3155.0
JAG1	3237	-943.0
JMY	3902	1880.0
JUN	2469	5472.0
JUNB	-2593	4931.0
KAT2A	-5053	-3388.0
KAT2B	-3340	-2881.0
KAT5	447	1402.0
KAT6A	3849	3678.0
KCTD1	-2989	1558.0
KCTD15	-3871	-4794.0
KCTD6	2748	2384.0
KDM5B	4870	4075.0
KLF4	3126	4618.0
KMT2A	4833	3012.0
KMT2C	4070	-734.0
KMT2D	-1176	515.0
KMT2E	3381	2429.0
KRAS	3546	5146.0
KRBA1	-948	-5019.0
L3MBTL2	-956	1208.0
LAMTOR1	-800	-4509.0
LAMTOR2	-1715	-4532.0
LAMTOR3	3134	781.0
LAMTOR4	-2977	-641.0
LAMTOR5	636	-1109.0
LBR	2244	-878.0
LDB1	-5369	-3841.0
LEO1	2784	-714.0
LGALS3	1062	4689.0
LIFR	-994	-4778.0
LMO2	-1725	795.0
LRPPRC	1656	-4711.0
LSM10	-3826	1128.0
LSM11	-2895	-1506.0
MAF	-5349	-2988.0
MAGOH	4561	555.0
MAGOHB	2239	-1880.0
MAML1	2770	4362.0
MAML2	2681	2618.0
MAML3	-2079	1098.0
MAMLD1	-1668	2661.0
MAP2K6	1456	-4331.0
MAPK1	1988	-969.0
MAPK11	-3385	1370.0
MAPK14	-1562	-2824.0
MAPK3	-1024	4464.0
MAPKAP1	-405	1545.0
MAX	-2352	-1748.0
MBD3	-3419	804.0
MDC1	841	2652.0
MDM2	3253	5156.0
MDM4	2051	-1866.0
MEAF6	1066	465.0
MECP2	-1705	-1071.0
MED1	4772	358.0
MED10	4087	2486.0
MED12	-2130	-467.0
MED13	4601	5355.0
MED14	2781	-2531.0
MED15	1233	5257.0
MED16	-2476	-4399.0
MED17	4255	2011.0
MED20	3604	-1597.0
MED23	3909	2920.0
MED24	-4786	-3269.0
MED25	2948	-1517.0
MED26	4038	2729.0
MED27	1227	3367.0
MED30	2307	-538.0
MED31	4638	-2680.0
MED4	4026	2219.0
MED6	4813	-1254.0
MED7	4316	1176.0
MED8	4163	-2286.0
MEF2C	-4610	2307.0
MEN1	1348	426.0
MET	-3529	4440.0
MGA	4502	-2399.0
MLH1	-1210	-3920.0
MLLT1	472	3521.0
MLLT3	3202	4762.0
MLST8	-3485	-1820.0
MNAT1	830	-3106.0
MOV10	-4127	-294.0
MSH2	4647	-4959.0
MSTN	-3974	3911.0
MT-CO1	-3167	-4401.0
MTA2	3682	-1298.0
MTOR	-1191	583.0
MYC	3994	185.0
MYL9	-4777	-1049.0
NABP1	-3908	5475.0
NABP2	-279	-3357.0
NBN	1286	-1789.0
NCBP1	-1736	4720.0
NCBP2	4188	-2519.0
NCOR1	2625	-1011.0
NCOR2	-5167	-143.0
NDRG1	-102	-267.0
NDUFA4	-393	-2605.0
NEDD4L	4279	95.0
NELFA	356	3429.0
NELFB	-1196	2017.0
NELFCD	1896	-2826.0
NELFE	-2178	3913.0
NFATC2	-3264	2685.0
NFKB1	-4233	2228.0
NFYA	4965	4520.0
NFYB	1632	-4319.0
NFYC	-1444	-2678.0
NOC2L	1374	2996.0
NOP2	3472	5052.0
NOTCH1	-5460	-194.0
NOTCH3	-1225	2260.0
NR1D1	-5185	-383.0
NR1D2	1828	-3986.0
NR1H2	2288	2282.0
NR1H3	-3630	-3340.0
NR2C1	679	-3166.0
NR2C2	1579	-1470.0
NR2C2AP	2640	2320.0
NR2F1	-4439	3126.0
NR2F6	-4543	712.0
NR3C1	985	425.0
NR3C2	-1723	1466.0
NR4A1	-5560	-1228.0
NR4A2	-1651	-502.0
NR4A3	-4264	3637.0
NR6A1	-2345	2523.0
NRBF2	4966	-1758.0
NRBP1	2753	4086.0
NUAK1	-2765	3532.0
NUDT21	3626	432.0
PAF1	2516	-2851.0
PARP1	-2423	278.0
PBRM1	3523	-980.0
PCBP4	-5523	-200.0
PCF11	-1597	-2273.0
PCGF5	1470	3462.0
PCGF6	1159	3236.0
PCNA	1329	5271.0
PDPK1	3443	3947.0
PERP	831	2446.0
PHAX	4729	-485.0
PHC1	456	3606.0
PHC2	-3719	5142.0
PHC3	3141	957.0
PHF20	819	949.0
PIN1	-3515	-3234.0
PINK1	-4060	-2958.0
PIP4K2A	4108	4105.0
PIP4K2C	2827	4009.0
PITX2	-5256	-2114.0
PLAGL1	-4577	4670.0
PLK2	4764	4721.0
PLK3	-1003	3004.0
PLXNA4	-319	1224.0
PMAIP1	-4203	4118.0
PML	3338	3242.0
PMS2	806	-1226.0
POLDIP3	-1320	5061.0
POLR2A	3861	5366.0
POLR2B	4509	-3401.0
POLR2C	4529	-4002.0
POLR2D	1669	3230.0
POLR2E	-667	148.0
POLR2G	89	4349.0
POLR2H	-3927	2213.0
POLR2I	-154	-2504.0
POLR2K	2480	-3599.0
POLR2L	-4314	-1126.0
POU2F1	3019	-1366.0
POU4F1	-1640	-4268.0
PPARA	-4997	-2863.0
PPARD	-4213	2330.0
PPARG	-1621	-2602.0
PPARGC1A	-4212	-4916.0
PPARGC1B	-5257	-2496.0
PPM1A	3438	-2375.0
PPM1D	1792	1169.0
PPP1R13B	3413	1613.0
PPP1R13L	-3554	3083.0
PPP2CA	4482	1672.0
PPP2CB	2458	2352.0
PPP2R1A	-4013	-681.0
PPP2R1B	3028	3194.0
PPP2R5C	-2508	-293.0
PRDM1	-50	-4190.0
PRDX1	605	2863.0
PRDX2	-5293	-3921.0
PRDX5	-3356	-3915.0
PRELID1	1651	4808.0
PRKAA1	3389	2399.0
PRKAA2	-3219	-2647.0
PRKAB1	3436	2257.0
PRKAB2	-2332	-3109.0
PRKACA	-4691	-4303.0
PRKAG1	2103	-3125.0
PRKAG2	-3237	502.0
PRKAG3	-5537	-2369.0
PRKCQ	-5095	-4724.0
PRMT5	933	2092.0
PRMT6	2063	4057.0
PRR5	-837	161.0
PSMA1	2820	4043.0
PSMA3	3434	-1035.0
PSMA4	769	-1962.0
PSMA6	2199	-1657.0
PSMA7	-2980	-1038.0
PSMB1	954	-1037.0
PSMB10	-1800	-831.0
PSMB2	618	-67.0
PSMB4	-235	-559.0
PSMB5	-4113	-2597.0
PSMB6	-793	-1795.0
PSMB7	-831	-2699.0
PSMB8	-675	-2510.0
PSMB9	-1611	-3558.0
PSMC1	449	1146.0
PSMC2	-1311	3386.0
PSMC3	-2439	-1846.0
PSMC4	2724	-205.0
PSMC5	1212	-1680.0
PSMC6	-2520	3114.0
PSMD1	2619	3210.0
PSMD10	-1227	361.0
PSMD11	995	5504.0
PSMD12	3831	-462.0
PSMD13	821	532.0
PSMD14	-635	3746.0
PSMD2	-713	741.0
PSMD3	-3343	-354.0
PSMD4	-214	968.0
PSMD5	1807	4479.0
PSMD6	3537	-3784.0
PSMD7	-2329	410.0
PSMD8	-3171	4292.0
PSMD9	4204	-3586.0
PSME1	-2771	-2861.0
PSME2	-4085	-41.0
PSME3	3333	491.0
PSME4	1960	2319.0
PSMF1	683	-1768.0
PTEN	2797	4830.0
PTPN1	1531	4935.0
PTPN11	-1575	3105.0
PTPN4	-1408	5055.0
RABGGTA	-1231	-3826.0
RABGGTB	-945	-2383.0
RAD1	3205	3596.0
RAD17	2273	-1057.0
RAD50	306	-1413.0
RAD51	63	-3321.0
RAD51D	-876	399.0
RAD9A	-3149	-726.0
RARA	-5250	1555.0
RARB	-2995	-231.0
RARG	-4431	-1193.0
RB1	-2449	831.0
RBBP4	1072	728.0
RBBP5	4628	1244.0
RBBP7	-924	-1007.0
RBBP8	3047	3887.0
RBFOX1	-5102	-4362.0
RBL1	-1617	-993.0
RBL2	-242	-1988.0
RBM14	4731	4683.0
RBPJ	305	5264.0
RBX1	-733	-2400.0
RELA	1783	4454.0
RFC2	622	-3123.0
RFC3	2151	3463.0
RFC4	3542	-36.0
RFC5	1409	3702.0
RFFL	1079	-3627.0
RGCC	-1145	5503.0
RHEB	172	1360.0
RHNO1	-4573	-260.0
RICTOR	3562	1082.0
RING1	-1968	-3185.0
RMI1	4517	1974.0
RMI2	-2759	-2576.0
RNF111	3964	5247.0
RNF2	3038	4841.0
RNF34	3719	-1003.0
RNGTT	4414	-1456.0
RNMT	4864	3622.0
RNPS1	681	-2204.0
RORA	-5056	2669.0
RORC	-5248	-3275.0
RPA1	-1837	-2287.0
RPA2	2889	-3725.0
RPA3	2702	-4228.0
RPAP2	3147	-617.0
RPRD1A	-3380	-398.0
RPRD1B	2187	-2100.0
RPRD2	4039	1262.0
RPS27A	783	-2165.0
RPTOR	-4596	3929.0
RQCD1	4265	2047.0
RRAGA	2383	4039.0
RRAGB	-366	123.0
RRAGC	2091	1975.0
RRAGD	-4673	-3366.0
RRM2B	-887	-4516.0
RTF1	-2993	-2890.0
RUNX1	-2434	5228.0
RUNX2	85	247.0
RXRA	-5519	1619.0
RXRB	-1250	-4283.0
RXRG	-4055	-290.0
RYBP	4895	4848.0
SARNP	569	-1380.0
SATB2	3702	5476.0
SCMH1	-5007	-899.0
SCO1	3577	-27.0
SCO2	-1941	-3526.0
SERPINE1	-211	5469.0
SESN1	-4227	1805.0
SESN2	-2604	5253.0
SESN3	4513	2809.0
SETD1A	2076	1573.0
SETD1B	-3010	3153.0
SGK1	1084	-4376.0
SIN3A	3397	2893.0
SIN3B	1030	316.0
SIRT1	4935	4355.0
SIRT3	-2752	-4933.0
SKI	-3187	2909.0
SKIL	1818	4329.0
SKP1	2028	-1286.0
SKP2	4205	4241.0
SLBP	2666	4469.0
SLC2A3	5004	2223.5
SLC38A9	969	1822.0
SLU7	4893	2372.0
SMAD1	-2920	5408.0
SMAD2	1125	5372.0
SMAD3	-3794	-3710.0
SMAD4	2354	2716.0
SMAD6	2009	-1203.0
SMAD7	-1051	3680.0
SMARCA2	-2904	-4911.0
SMARCA4	-3874	863.0
SMARCB1	-474	548.0
SMARCC1	-4311	1930.0
SMARCC2	-3726	-172.0
SMARCD1	2718	3700.0
SMARCD2	319	1355.0
SMARCD3	-5399	-3136.0
SMARCE1	1364	2546.0
SMURF1	4443	-1337.0
SMURF2	1070	5348.0
SMYD2	-1305	-3228.0
SNAPC1	3749	4945.0
SNAPC2	3411	-464.0
SNAPC3	3029	1116.0
SNAPC4	363	1159.0
SNAPC5	-703	-3560.0
SNRPB	3761	-2577.0
SNRPD3	2384	-3590.0
SNRPE	3421	-1387.0
SNRPF	3777	-2345.0
SNRPG	3179	3068.0
SNW1	3618	4892.0
SOCS3	-283	4943.0
SOCS4	4713	1539.0
SOD2	-1568	-4837.0
SOX9	2175	5346.0
SP1	1787	967.0
SPP1	1162	2350.0
SRC	-3910	3763.0
SREBF1	-5230	273.0
SRRM1	2285	-2017.0
SRRT	4962	350.0
SRSF1	1871	-1493.0
SRSF11	3911	-1990.0
SRSF3	2586	1697.0
SRSF4	1929	3741.0
SRSF5	1997	-3060.0
SRSF6	1798	2387.0
SRSF7	3545	2132.0
SRSF9	3543	2675.0
SSRP1	1755	1765.0
SSU72	1324	-3343.0
STAT1	236	-3457.0
STEAP3	-5586	-4859.0
STK11	-4884	-3985.0
STUB1	-2898	-3668.0
SUMO1	4213	-262.0
SUPT16H	3885	4417.0
SUPT4H1	3648	-1692.0
SUPT5H	1321	4377.0
SUPT6H	4807	5334.0
SURF1	-1748	-3290.0
SUZ12	3871	4598.0
SYMPK	-3207	-1626.0
TACO1	651	-4903.0
TAF1	1708	4363.0
TAF10	-273	547.0
TAF11	2962	-1678.0
TAF12	3100	3716.0
TAF13	4749	1646.0
TAF2	4591	3536.0
TAF3	4294	4087.0
TAF4	-1340	4027.0
TAF4B	4967	5489.0
TAF5	4309	1473.0
TAF6	-912	-885.0
TAF7	4717	5281.0
TAF8	2937	1493.0
TAF9B	1874	-618.0
TBL1XR1	1876	528.0
TBP	1137	3931.0
TCEA1	4037	163.0
TCF12	1614	4852.0
TCF3	-2289	2738.0
TCF7	1204	-1623.0
TCF7L1	-3205	750.0
TCF7L2	-74	716.0
TEAD1	-4292	2647.0
TEAD2	323	-1534.0
TEAD3	-4846	-1975.0
TEAD4	-5380	-2538.0
TFDP1	-2245	-3110.0
TFDP2	4029	-4963.0
TGFB1	-3111	4516.0
TGIF1	-2131	2058.0
THBS1	762	5034.0
THOC1	2868	2971.0
THOC2	4510	561.0
THOC3	2831	-3387.0
THOC5	4842	-589.0
THOC6	-904	2005.0
THOC7	-873	-3232.0
THRA	-5483	-5088.0
THRB	-1313	-2078.0
TJP1	405	-780.0
TMEM219	-3222	-1497.0
TMEM55B	3859	1390.0
TNFRSF10A	-3936	485.5
TNFRSF10B	-1612	485.5
TNFRSF10C	-2321	485.5
TNFRSF10D	-3227	485.5
TNKS1BP1	-4407	3365.0
TNRC6A	3585	2923.0
TNRC6B	3118	-2855.0
TNRC6C	-2020	1056.0
TOP3A	2607	3192.0
TOPBP1	2183	5010.0
TP53	575	3128.0
TP53BP2	4687	4246.0
TP53INP1	-2309	-1204.0
TP53RK	3992	-1473.0
TP63	3691	737.0
TPX2	3446	2866.0
TRIAP1	901	-1776.0
TRIM28	4209	4779.0
TRIM33	2796	3628.0
TRIM63	-4866	-657.0
TSC1	2577	2054.0
TSC2	-4999	760.0
TTC5	3302	1251.0
TWIST1	2624	1741.0
TXN	1855	4827.0
TXNRD1	-2444	4222.0
U2AF2	4337	2964.0
UBC	2672	3877.0
UBE2C	4949	-3635.0
UBE2D1	-1588	-4657.0
UBE2D3	1424	5192.0
UBE2E1	-1132	-881.0
UBE2I	1246	733.0
UBE2S	4441	2868.0
UPF3B	1586	-4490.0
USP2	-5039	-3331.0
USP7	3857	2483.0
USP9X	1458	-295.0
UXT	-248	1389.0
VEGFA	-4571	-5070.0
VWA9	2598	187.0
WDR33	3143	-994.0
WDR5	-1608	-1067.0
WDR61	-1148	-234.0
WRN	98	2942.0
WWOX	1055	-3485.0
WWP1	-1200	-3658.0
WWTR1	-2503	3401.0
YAF2	182	-3980.0
YAP1	-476	5038.0
YEATS4	3247	2348.0
YES1	-176	-836.0
YWHAB	3680	3468.0
YWHAE	1394	-2051.0
YWHAG	-2372	1012.0
YWHAH	-2777	3808.0
YWHAQ	963	3949.0
YWHAZ	2019	4919.0
ZC3H8	-3996	-4393.0
ZFHX3	-2823	417.0
ZFP1	777	319.0
ZFP14	-1564	-3984.0
ZFP2	-2603	-3410.0
ZFP28	4189	-3006.0
ZFP30	516	-4729.0
ZFP37	4076	4737.0
ZFP69	3315	-835.0
ZFP90	480	1589.0
ZFPM1	71	-424.0
ZIK1	4897	-2639.0
ZKSCAN1	-1405	3323.0
ZKSCAN3	630	-1709.5
ZKSCAN4	4031	-1709.5
ZKSCAN5	4612	4666.0
ZKSCAN7	-1769	-4305.0
ZKSCAN8	3190	-4662.0
ZNF101	4947	-4507.0
ZNF112	2487	-2356.0
ZNF12	2721	-1854.0
ZNF124	4126	-4507.0
ZNF143	1822	4676.0
ZNF169	-1838	2469.0
ZNF18	3432	731.0
ZNF180	3868	837.0
ZNF189	1916	-2878.0
ZNF202	2190	-29.0
ZNF205	-2430	-1059.0
ZNF212	554	209.0
ZNF213	-509	-2872.0
ZNF23	1671	-2324.0
ZNF235	2757	-5063.0
ZNF248	-2815	348.0
ZNF25	-3296	4949.0
ZNF250	-514	-2944.0
ZNF263	4581	565.0
ZNF274	4186	-3242.0
ZNF282	-3935	884.0
ZNF286A	3048	-3466.0
ZNF287	3780	248.0
ZNF3	3939	-3198.0
ZNF317	3402	2126.0
ZNF324	2644	870.5
ZNF324B	2800	870.5
ZNF334	961	4095.0
ZNF347	4334	-1317.5
ZNF354A	4577	-3937.0
ZNF354C	1442	-422.0
ZNF385A	-5211	2561.0
ZNF394	4721	-3911.0
ZNF398	1779	4090.0
ZNF416	4497	-1847.0
ZNF420	16	3556.0
ZNF426	3687	2349.0
ZNF429	-5017	-4551.5
ZNF43	4092	-4243.5
ZNF436	3688	-4649.0
ZNF445	-3447	-3700.0
ZNF446	-63	-3167.0
ZNF45	4715	-2195.0
ZNF454	921	1872.0
ZNF493	-3572	-4243.5
ZNF496	-2663	2740.0
ZNF521	629	2592.0
ZNF551	4427	-2653.0
ZNF559	4814	-3962.5
ZNF560	3600	71.0
ZNF561	-185	-2047.5
ZNF562	-55	-2047.5
ZNF566	549	2782.0
ZNF569	2722	-2125.0
ZNF585A	4317	-4688.0
ZNF597	3559	1798.0
ZNF606	1719	-4027.0
ZNF641	-4105	1543.0
ZNF655	1508	2730.0
ZNF660	-856	-3686.0
ZNF664	-1330	1319.0
ZNF665	359	-1317.5
ZNF667	1646	373.0
ZNF668	3548	1356.0
ZNF669	4901	-4507.0
ZNF678	3662	-3749.0
ZNF688	-1703	2294.0
ZNF689	2277	2174.0
ZNF691	1491	-4339.0
ZNF692	-475	-2200.0
ZNF697	-787	4142.0
ZNF703	-5506	-3976.0
ZNF704	-3376	1763.0
ZNF706	99	-3945.0
ZNF707	-1032	1219.0
ZNF710	-2142	-5087.0
ZNF720	4946	-5012.5
ZNF721	4971	-2996.5
ZNF738	4987	-5012.5
ZNF740	-4838	-3922.0
ZNF746	736	779.0
ZNF764	-1896	4603.0
ZNF770	4367	-3768.0
ZNF771	107	-2723.0
ZNF775	-3056	-3721.0
ZNF777	657	-960.0
ZNF790	-3148	-1937.0
ZNF791	4620	-4768.0
ZNF839	-808	-2227.0
ZSCAN25	2848	2086.0

---

---

Cell Cycle, Mitotic

Cell Cycle, Mitotic

metric	value
setSize	397
pMANOVA	7.59e-11
p.adjustMANOVA	2.53e-09
s.dist	0.216
s.human	0.182
s.mouse	0.116
p.human	6.23e-10
p.mouse	8.34e-05

Top 20 genes

Gene	human	mouse
PPME1	4727	5508
NUP98	4235	5486
FBXW11	4385	5178
RAD21	4417	4961
NUP54	4508	4751
HSP90AA1	3656	5525
CDC25B	4652	4269
DBF4	4260	4558
CEP152	4492	4285
NUP153	4762	4031
EML4	4736	4004
RAB1A	3634	5087
HAUS3	3748	4846
MAPRE1	3454	5215
PPP2R5A	4590	3889
SKP2	4205	4241
CCNE1	4388	4060
TNPO1	3184	5474
NUP205	4438	3917
KPNB1	3619	4744

Click HERE to show all gene set members

All member genes

	human	mouse
AAAS	-3476	40.0
ABL1	-4533	1377.0
ACTR1A	-4126	3959.0
AHCTF1	4662	2760.0
AJUBA	-4112	-1867.0
AKAP9	-573	-4367.0
AKT1	-4954	1242.0
AKT2	-4057	-3488.0
AKT3	1343	2419.0
ALMS1	4347	1257.0
ANAPC1	572	-470.0
ANAPC10	1974	2927.0
ANAPC11	-3265	-2502.0
ANAPC15	-3393	1658.0
ANAPC16	-3612	-3229.0
ANAPC2	-2185	-1142.0
ANAPC4	-720	-3761.0
ANAPC5	1284	-3105.0
ANAPC7	1595	882.0
ANKLE2	1499	366.0
ARPP19	2927	3170.0
AURKA	3811	-2443.0
B9D2	1676	-3727.0
BANF1	-2281	-1690.0
BLZF1	4266	-284.0
BORA	4768	2662.0
BTRC	-1187	-2761.0
BUB3	4201	-1316.0
CABLES1	-4484	662.0
CC2D1B	1025	2921.0
CCNA2	3061	2333.0
CCND1	757	1643.0
CCND2	225	2762.0
CCND3	786	1243.0
CCNE1	4388	4060.0
CCNE2	4667	-521.0
CCNH	3825	-1939.0
CCP110	4605	2327.0
CDC14A	957	-850.0
CDC16	86	-1235.0
CDC23	3850	1048.0
CDC25A	4090	3965.0
CDC25B	4652	4269.0
CDC26	2750	2001.0
CDC27	665	3905.0
CDC7	2421	3646.0
CDK1	1580	3204.0
CDK11A	167	-1445.5
CDK11B	1690	-1445.5
CDK2	849	2902.0
CDK4	703	2603.0
CDK5RAP2	-3037	414.0
CDK6	1090	2660.0
CDK7	1571	326.0
CDKN1A	-4927	3046.0
CDKN1B	-3284	-2637.0
CDKN1C	-5394	-2348.0
CDKN2B	-2827	-832.0
CDKN2C	3612	259.0
CDKN2D	142	-206.0
CENPC	3555	-133.0
CENPJ	1720	200.0
CENPL	3768	3397.0
CENPO	1005	3332.0
CENPQ	1344	5114.0
CENPT	-2196	4477.0
CEP135	1891	-215.0
CEP152	4492	4285.0
CEP164	3699	4174.0
CEP192	2073	659.0
CEP250	3192	-2201.0
CEP290	3352	-1031.0
CEP41	4357	2959.0
CEP57	611	-1339.0
CEP63	-2491	-3687.0
CEP70	-3094	-1341.0
CEP76	3163	4149.0
CEP78	3895	2253.0
CETN2	-587	-1606.0
CHMP2A	1155	2070.0
CHMP2B	967	-4699.0
CHMP3	-3919	1246.0
CHMP4B	-1125	-1336.0
CHMP6	-4368	-1833.0
CHMP7	1743	-1108.0
CKAP5	-3973	78.0
CKS1B	1446	4954.0
CLASP1	-3713	3198.0
CLASP2	2507	2478.0
CLIP1	418	-371.0
CNEP1R1	1729	379.0
CNTRL	4333	-4470.0
CSNK1D	-3539	4717.0
CSNK1E	-5045	3424.0
CSNK2A1	1796	-2551.0
CSNK2A2	2123	2667.0
CSNK2B	1917	-1746.0
CTDNEP1	-2509	-3777.0
CUL1	-3121	-833.0
DBF4	4260	4558.0
DCTN1	-347	-4056.0
DCTN2	-3157	-3324.0
DCTN3	-943	1919.0
DHFR	-3638	2914.5
DNA2	37	3262.0
DSN1	2075	-665.0
DYNC1H1	-1442	1264.0
DYNC1I2	2591	172.0
DYNC1LI1	2883	981.0
DYNC1LI2	1750	3473.0
DYNLL1	-1331	3935.0
DYRK1A	-2401	4754.0
E2F1	-529	4887.0
E2F3	-4683	2636.0
E2F4	-439	4952.0
E2F5	-249	1172.0
E2F6	650	-3961.0
EMD	-651	533.0
EML4	4736	4004.0
ENSA	-114	-163.0
EP300	3403	2309.0
ESCO1	680	-926.0
ESPL1	408	4532.0
FBXL18	1610	-956.0
FBXW11	4385	5178.0
FEN1	4094	-1467.0
FKBPL	4474	3796.0
FZR1	-1244	3161.0
GINS1	441	-336.0
GINS3	-1006	2153.0
GINS4	-1475	-1141.0
GMNN	4714	-3302.0
GOLGA2	919	-3694.0
GORASP1	-4615	-2930.0
GORASP2	2697	5074.0
GSK3B	897	4692.0
H2AFX	2356	5181.0
HAUS1	1263	-754.0
HAUS2	2905	3427.0
HAUS3	3748	4846.0
HAUS4	-2191	-1521.0
HAUS6	3590	2060.0
HAUS8	758	3827.0
HDAC8	209	-3383.0
HSP90AA1	3656	5525.0
HSP90AB1	-639	5203.0
INCENP	3676	1455.0
IST1	3827	3890.0
ITGB3BP	1048	-2794.0
JAK2	-2569	-2171.0
KIF18A	3832	2448.0
KIF23	1216	2656.0
KIF2A	-4390	4073.0
KPNB1	3619	4744.0
LBR	2244	-878.0
LCMT1	729	-2516.0
LEMD2	-1073	-727.0
LEMD3	3330	789.0
LIG1	-3127	898.0
LIN37	-1988	3202.0
LIN52	915	-3656.0
LIN54	4080	-750.0
LIN9	1166	-3476.0
LMNA	-4692	5452.0
LMNB1	3392	648.0
LPIN1	-2877	-4450.0
LPIN2	3569	3805.0
LPIN3	-1052	2283.0
LYN	785	2842.0
MAD1L1	-3382	1367.0
MAD2L1	1101	1981.0
MAPK1	1988	-969.0
MAPK3	-1024	4464.0
MAPRE1	3454	5215.0
MAU2	-3188	439.0
MAX	-2352	-1748.0
MCM2	-3977	-144.0
MCM3	600	4066.0
MCM4	-610	4411.0
MCM5	-1490	4615.0
MCM6	3462	4930.0
MCM7	2515	864.0
MCM8	-3355	-4264.0
MCPH1	2176	571.0
MIS12	2400	5092.0
MNAT1	830	-3106.0
MYC	3994	185.0
MZT1	3517	-3577.0
MZT2A	-3883	-2755.5
MZT2B	-3442	-2755.5
NCAPD2	4017	-3639.0
NCAPD3	3002	-4465.0
NCAPG2	-13	-219.0
NCAPH	1129	2968.0
NCAPH2	-1845	-165.0
NDC1	1273	-322.0
NDE1	4322	-1640.0
NDEL1	4631	3278.0
NEDD1	1034	-212.0
NEK6	-5042	3707.0
NEK7	535	-1025.0
NEK9	-2856	1690.0
NIPBL	4675	-1061.0
NME7	2020	722.0
NUDC	3212	-860.0
NUMA1	-4395	143.0
NUP107	3232	3195.0
NUP133	889	-2580.0
NUP153	4762	4031.0
NUP155	4306	2897.0
NUP160	3998	2314.0
NUP188	2117	4593.0
NUP205	4438	3917.0
NUP214	3124	1845.0
NUP35	4571	2515.0
NUP37	-327	-873.0
NUP43	4562	193.0
NUP54	4508	4751.0
NUP85	3181	227.0
NUP88	1244	1407.0
NUP93	-1503	5229.0
NUP98	4235	5486.0
ODF2	1954	1134.0
OFD1	811	-1859.0
OPTN	1980	-1444.0
ORC2	1022	5065.0
ORC3	-1627	-3647.0
ORC4	3929	2552.0
ORC5	4429	-1666.0
ORC6	2184	-3079.0
PAFAH1B1	-2026	1737.0
PCM1	1788	-1831.0
PCNA	1329	5271.0
PCNT	-1269	-5032.0
PDS5A	1248	976.0
PDS5B	-3191	-2058.0
PHF8	3393	1834.0
PHLDA1	-3126	5172.0
PLK4	3581	2637.0
POLA1	1944	2596.0
POLA2	-173	-4473.0
POLD1	-3218	-1289.0
POLD2	-4806	-1924.0
POLD3	3486	1800.0
POLD4	-2084	3734.0
POLE	-3659	1758.0
POLE2	1264	2303.0
POLE3	4335	3627.0
POLE4	409	2317.0
PPME1	4727	5508.0
PPP1CB	-1374	-3335.0
PPP1CC	4081	-1627.0
PPP1R12A	4131	4053.0
PPP1R12B	-5005	2701.0
PPP2CA	4482	1672.0
PPP2CB	2458	2352.0
PPP2R1A	-4013	-681.0
PPP2R1B	3028	3194.0
PPP2R2A	2264	1164.0
PPP2R2D	-2153	1214.0
PPP2R5A	4590	3889.0
PPP2R5B	-1524	-765.0
PPP2R5C	-2508	-293.0
PPP2R5D	-3449	-620.0
PPP2R5E	4644	2107.0
PRIM1	311	3175.0
PRIM2	3544	3971.0
PRKACA	-4691	-4303.0
PRKAR2B	3460	1006.0
PRKCA	-2938	1125.0
PSMA1	2820	4043.0
PSMA3	3434	-1035.0
PSMA4	769	-1962.0
PSMA6	2199	-1657.0
PSMA7	-2980	-1038.0
PSMB1	954	-1037.0
PSMB10	-1800	-831.0
PSMB2	618	-67.0
PSMB4	-235	-559.0
PSMB5	-4113	-2597.0
PSMB6	-793	-1795.0
PSMB7	-831	-2699.0
PSMB8	-675	-2510.0
PSMB9	-1611	-3558.0
PSMC1	449	1146.0
PSMC2	-1311	3386.0
PSMC3	-2439	-1846.0
PSMC4	2724	-205.0
PSMC5	1212	-1680.0
PSMC6	-2520	3114.0
PSMD1	2619	3210.0
PSMD10	-1227	361.0
PSMD11	995	5504.0
PSMD12	3831	-462.0
PSMD13	821	532.0
PSMD14	-635	3746.0
PSMD2	-713	741.0
PSMD3	-3343	-354.0
PSMD4	-214	968.0
PSMD5	1807	4479.0
PSMD6	3537	-3784.0
PSMD7	-2329	410.0
PSMD8	-3171	4292.0
PSMD9	4204	-3586.0
PSME1	-2771	-2861.0
PSME2	-4085	-41.0
PSME3	3333	491.0
PSME4	1960	2319.0
PSMF1	683	-1768.0
PTTG1	4843	-4670.0
RAB1A	3634	5087.0
RAB1B	-2997	-3742.0
RAB2A	1999	-1496.0
RAB8A	3378	3986.0
RAD21	4417	4961.0
RAE1	4471	3078.0
RAN	2329	575.0
RANBP2	4470	-562.0
RANGAP1	483	4468.0
RB1	-2449	831.0
RBBP4	1072	728.0
RBL1	-1617	-993.0
RBL2	-242	-1988.0
RBX1	-733	-2400.0
RCC1	997	4917.0
RCC2	4178	3180.0
RFC1	4641	2623.0
RFC2	622	-3123.0
RFC3	2151	3463.0
RFC4	3542	-36.0
RFC5	1409	3702.0
RPA1	-1837	-2287.0
RPA2	2889	-3725.0
RPA3	2702	-4228.0
RPS27A	783	-2165.0
SDCCAG8	1021	2266.0
SEC13	730	938.0
SEH1L	1085	4110.0
SET	3683	1612.0
SFI1	-1212	-3175.0
SIRT2	-4852	-682.0
SKA2	2399	946.0
SKP1	2028	-1286.0
SKP2	4205	4241.0
SMC1A	3824	-118.0
SMC2	2477	3897.0
SMC3	4878	2611.0
SMC4	4127	1198.0
SPAST	3456	-976.0
SRC	-3910	3763.0
SSNA1	-2879	-2145.0
STAG1	4246	505.0
STAG2	31	-897.0
SUMO1	4213	-262.0
TAOK1	1644	130.0
TFDP1	-2245	-3110.0
TFDP2	4029	-4963.0
TK1	-3225	-65.0
TMPO	4574	-1098.0
TNPO1	3184	5474.0
TOP2A	4691	3074.0
TP53	575	3128.0
TPR	2984	275.0
TPX2	3446	2866.0
TUBA1A	-5228	4221.0
TUBA1B	-5324	5343.0
TUBA1C	-4883	5415.0
TUBA4A	-5342	240.0
TUBA8	-1116	-946.0
TUBB	-3118	5321.0
TUBB2A	-4676	5002.0
TUBB2B	-4704	5335.0
TUBB4B	430	4642.0
TUBB6	-5060	5524.0
TUBG1	-3728	-3871.0
TUBG2	93	-148.0
TUBGCP2	-3362	-2968.0
TUBGCP3	2352	2516.0
TUBGCP4	4074	1836.0
TUBGCP6	-3953	-1591.0
TYMS	-2042	3786.0
UBC	2672	3877.0
UBE2C	4949	-3635.0
UBE2D1	-1588	-4657.0
UBE2E1	-1132	-881.0
UBE2I	1246	733.0
UBE2S	4441	2868.0
USO1	-738	3388.0
VPS4A	-1545	-2729.0
VRK1	1696	-3373.0
VRK2	1461	-4163.0
WEE1	-4561	3159.0
XPO1	990	2133.0
YWHAE	1394	-2051.0
YWHAG	-2372	1012.0
ZW10	1474	3364.0
ZWINT	2778	5457.0

---

---

Signaling by GPCR

Signaling by GPCR

metric	value
setSize	270
pMANOVA	9.23e-11
p.adjustMANOVA	2.99e-09
s.dist	0.225
s.human	-0.211
s.mouse	0.0785
p.human	2.92e-09
p.mouse	0.0274

Top 20 genes

Gene	human	mouse
RHOC	-4944	4844
P2RY6	-4646	5147
XK	-5173	4570
ARHGEF2	-4945	4225
LDLR	-3949	5260
TIAM2	-3379	5429
ABR	-5353	3387
RGS3	-5494	3152
CYSLTR1	-4110	4012
CXCL12	-4998	3271
CAMKK1	-3959	4041
SRC	-3910	3763
VAV2	-4959	2847
SDC3	-4619	2991
SMO	-4360	3150
OPN3	-2839	4784
GNA12	-3059	4306
ARHGEF40	-5458	2410
NET1	-5146	2540
FGD1	-3972	3284

Click HERE to show all gene set members

All member genes

	human	mouse
ABHD12	-778	-482.0
ABHD6	-2808	-530.0
ABR	-5353	3387.0
ADCY1	-3780	-756.0
ADCY2	-4820	-4790.0
ADCY3	338	612.0
ADCY5	1967	3217.0
ADCY6	-4515	-3045.0
ADCY7	-2820	3300.0
ADCY9	-4889	-2586.0
ADM	-1822	-3530.0
ADRA2A	-4661	-686.0
ADRB2	-1092	-929.0
AGRN	-4903	783.0
AGT	-4723	-2282.0
AGTR1	1167	-2662.0
AHCYL1	-3386	2570.0
AKAP13	1322	667.0
AKR1B10	2786	-1511.5
AKT1	-4954	1242.0
AKT2	-4057	-3488.0
AKT3	1343	2419.0
ANXA1	537	4783.0
APOE	-1428	-1396.0
APP	-2792	154.0
ARHGEF1	1054	-217.0
ARHGEF10L	-5596	682.0
ARHGEF11	-1199	2030.0
ARHGEF12	2630	5108.0
ARHGEF17	-5387	85.0
ARHGEF18	2304	-1935.0
ARHGEF2	-4945	4225.0
ARHGEF25	-2669	-1024.0
ARHGEF26	4815	3641.0
ARHGEF3	-4589	-823.0
ARHGEF37	-5129	127.0
ARHGEF4	-3700	211.0
ARHGEF40	-5458	2410.0
ARHGEF6	2856	4594.0
ARHGEF7	-3605	3212.0
ARHGEF9	-3989	-4009.0
ARRB1	-3133	2633.0
ARRB2	-1089	3740.0
C3	4311	-2705.0
CALCRL	2945	-2409.0
CALM1	-4464	1071.0
CAMK2A	-5527	-3819.0
CAMK2B	-5497	-2856.0
CAMK2D	-2223	5094.0
CAMK2G	-2097	-4184.0
CAMKK1	-3959	4041.0
CAMKK2	-4965	2096.0
CCL2	2620	5213.0
CD55	220	-3197.0
CDC42	3308	965.0
CDK5	-1007	-2874.0
CMKLR1	193	3314.0
CREB1	2179	-1920.0
CX3CR1	307	4879.0
CXCL12	-4998	3271.0
CXCL16	-920	-543.0
CYP4V2	-2707	73.0
CYSLTR1	-4110	4012.0
DAGLA	-5158	-1202.0
DAGLB	3782	-3217.0
DGKA	-2368	-2473.0
DGKB	-4489	-1599.0
DGKD	-5077	2121.0
DGKE	1911	-4489.0
DGKH	3337	3991.0
DGKQ	-2188	-3043.0
DGKZ	-5581	-3517.0
DHRS3	-611	377.0
ECE1	-1256	-853.0
ECE2	-294	1708.0
EDNRA	1038	2094.0
EDNRB	1473	-1220.0
EGFR	424	2978.0
F2R	1667	2871.0
F2RL1	3379	5479.0
FGD1	-3972	3284.0
FGD3	-3665	3129.0
FGD4	-4717	-3651.0
FNTA	1578	-3409.0
FNTB	-690	3507.0
FZD1	3076	4588.0
FZD10	-4859	-1478.0
FZD2	2092	2714.0
FZD4	-5151	-3086.0
FZD5	398	5121.0
FZD6	809	-1171.0
FZD7	1006	-1637.0
FZD8	-3582	-2814.0
FZD9	-5079	-4128.0
GABBR1	-2887	-778.0
GNA11	-1689	2150.0
GNA12	-3059	4306.0
GNA13	-209	5323.0
GNAI1	183	1373.0
GNAI2	800	2142.0
GNAI3	4221	4647.0
GNAL	-3374	3533.0
GNAQ	4906	4533.0
GNAS	-3163	-1742.0
GNB1	177	5374.0
GNB2	-3870	1232.0
GNB3	-3272	-676.0
GNB4	-3491	1634.0
GNB5	879	-2818.0
GNG11	4695	-4457.0
GNG12	612	604.0
GNG2	802	-2139.0
GNG5	415	-3220.0
GNG7	-2742	-4220.0
GPC1	-5269	-1574.0
GPC4	-5170	-4334.0
GPC6	-2385	1959.0
GPR35	-3228	2443.0
GPSM1	-3915	1306.0
GPSM2	-3093	3500.0
GRB2	-4050	3027.0
GRK4	-1206	945.0
GRK5	-1067	-563.0
GRK6	-1110	2111.0
HBEGF	3484	5518.0
HEBP1	18	-537.0
HRAS	-4545	-4872.0
HSPG2	-5351	1532.0
HTR7	2315	-3527.0
ITPR1	4903	1106.0
ITPR2	1242	53.0
ITPR3	-3631	-2403.0
ITSN1	524	-2768.0
KALRN	-5340	-990.0
KPNA2	5007	4653.0
KRAS	3546	5146.0
LDLR	-3949	5260.0
LPAR1	-2162	3140.0
LPAR4	-1042	-1474.0
LPAR6	2280	1088.0
LRP1	-3652	3049.0
LRP10	-3203	1445.0
LRP12	4543	5259.0
MAPK1	1988	-969.0
MAPK3	-1024	4464.0
MAPK7	-729	2102.0
MCF2L	-5254	1060.0
METAP1	2806	-592.0
METAP2	0	1920.0
MGLL	-5374	-5059.0
MYO7A	-4056	2325.0
NAPEPLD	-3083	3144.0
NBEA	-4442	-507.0
NET1	-5146	2540.0
NLN	-3071	3578.0
NMB	-1654	-2613.0
NMT1	-1463	4510.0
NMT2	2059	4895.0
NRAS	4354	1003.0
OBSCN	-5563	-275.0
OPN3	-2839	4784.0
P2RY2	-5283	-3360.0
P2RY6	-4646	5147.0
PAK1	-5419	-4706.0
PDE10A	2072	2109.0
PDE1A	2411	-405.0
PDE3A	315	468.0
PDE4A	-3306	-5113.0
PDE4B	3915	-2949.0
PDE4C	-2010	-3176.0
PDE4D	-1433	-3425.0
PDE7A	-2549	-3215.0
PDE7B	-2696	-5066.0
PDE8A	-324	3438.0
PDPK1	3443	3947.0
PENK	634	-3005.0
PIK3CA	365	4218.0
PIK3R1	2896	-813.0
PIK3R3	3188	3545.0
PLA2G4A	603	4806.0
PLB1	-3857	-1943.0
PLCB1	-1580	-2084.0
PLCB3	-3863	993.0
PLCB4	-4274	-2681.0
PLEKHG2	-708	4175.0
PLEKHG5	-4706	-2803.0
PLXNB1	-5451	-185.0
PPP1CA	-4408	-15.0
PPP2CA	4482	1672.0
PPP2CB	2458	2352.0
PPP2R1A	-4013	-681.0
PPP2R1B	3028	3194.0
PPP2R5D	-3449	-620.0
PPP3CA	109	-1172.0
PPP3CB	-3435	-1839.0
PPP3CC	-3311	-2196.0
PREX1	188	2037.0
PRKACA	-4691	-4303.0
PRKACB	-2659	-360.0
PRKAR1A	-3106	203.0
PRKAR1B	-2442	3659.0
PRKAR2A	-2664	1823.0
PRKAR2B	3460	1006.0
PRKCA	-2938	1125.0
PRKCD	-4276	1141.0
PRKCE	-4307	-348.0
PRKCQ	-5095	-4724.0
PRKX	-1471	5241.0
PSAP	-2247	-4177.0
PTCH1	326	-672.0
PTCH2	-2962	1015.0
PTGER4	4219	2196.0
PTGIR	-370	3747.0
PTH1R	-2770	-90.0
PTHLH	-3836	-66.0
RAMP1	-5448	-646.0
RASGRF2	4373	-3126.0
RASGRP2	-2556	-4004.0
RBP1	2113	2547.0
RDH10	1095	4775.0
RDH11	2085	5274.0
RDH5	-3933	1560.0
REEP1	-5059	-2153.0
REEP2	-2968	-463.0
REEP3	2053	4553.0
REEP4	1148	4143.0
REEP5	-3723	-3834.0
REEP6	-1143	-450.0
RETSAT	2667	-4958.0
RGS10	-785	2024.0
RGS12	-4393	2043.0
RGS14	-5528	-1896.0
RGS16	-723	5075.0
RGS19	-2099	3025.0
RGS2	-581	4051.0
RGS3	-5494	3152.0
RGS4	1724	4741.0
RGS5	2155	-3665.0
RGS9BP	-2609	4386.0
RHOA	539	4106.0
RHOB	4609	4443.0
RHOC	-4944	4844.0
ROCK1	4876	3865.0
ROCK2	2205	1929.0
RPS6KA1	-1481	-1813.0
RPS6KA2	-4748	-4135.0
RPS6KA3	952	2296.0
S1PR1	2689	-1019.0
S1PR2	520	3630.0
S1PR3	2047	-31.0
SDC1	-2046	1023.0
SDC2	1756	4994.0
SDC3	-4619	2991.0
SDC4	-2393	5425.0
SMO	-4360	3150.0
SOS1	-1962	2326.0
SOS2	-563	-2646.0
SRC	-3910	3763.0
TAS1R1	-4010	-2497.0
TIAM1	2024	-347.0
TIAM2	-3379	5429.0
TRIO	1163	-378.0
UTS2R	-5043	1755.0
VAV2	-4959	2847.0
VAV3	187	-276.0
WNT11	-5040	-3868.0
WNT4	-5296	-1155.0
WNT5A	1837	-1443.0
WNT9A	-4855	-1823.0
XK	-5173	4570.0

---

---

Innate Immune System

Innate Immune System

metric	value
setSize	608
pMANOVA	1.37e-10
p.adjustMANOVA	4.33e-09
s.dist	0.153
s.human	-0.0431
s.mouse	0.146
p.human	0.0738
p.mouse	1.22e-09

Top 20 genes

Gene	human	mouse
SIRPA	-5627	4799
VCL	-4538	5383
SERPINB6	-5411	4298
PFKL	-4966	4614
MYO1C	-4842	4663
ANXA2	-4123	5407
ALDH3B1	-4529	4664
TMBIM1	-4812	4333
CYB5R3	-5395	3844
GALNS	-3960	5119
CKAP4	-3818	5046
AMPD3	-4286	4483
MAP2K3	-4716	3926
ACTR1B	-4206	4382
VAT1	-4095	4499
ASAH1	-3414	5351
TNFAIP3	-5203	3469
PRDX6	-3481	4983
ANO6	-4134	4182
S100A11	-3518	4873

Click HERE to show all gene set members

All member genes

	human	mouse
AAMP	2657.0	2106.0
ABI1	3792.0	3443.0
ABI2	-308.0	5438.0
ABL1	-4533.0	1377.0
ACLY	-2628.0	4526.0
ACTB	940.0	5427.0
ACTG1	-3075.0	5370.0
ACTR10	1853.0	920.0
ACTR1B	-4206.0	4382.0
ACTR2	3547.0	5008.0
ACTR3	1376.0	5496.0
ADAM10	-1509.0	1096.0
ADAM8	-2592.0	4767.0
AGA	1618.0	-5043.0
AGL	-4967.0	-4710.0
AGPAT2	-4979.0	-3846.0
AHCYL1	-3386.0	2570.0
ALAD	-3855.0	-4632.0
ALDH3B1	-4529.0	4664.0
ALDOA	-5575.0	-3960.0
ALDOC	1379.0	4069.0
ALPK1	-1737.0	1616.0
AMPD3	-4286.0	4483.0
ANO6	-4134.0	4182.0
ANPEP	-215.0	-216.0
ANXA2	-4123.0	5407.0
AP1M1	3732.0	1165.0
AP2A2	-1058.0	5459.0
APAF1	-3469.0	3979.0
APEH	-3390.0	-2532.0
APP	-2792.0	154.0
APRT	-3384.0	-223.0
ARHGAP9	-2941.0	-1677.0
ARL8A	-4586.0	3617.0
ARMC8	-194.0	-3654.0
ARPC1A	-120.0	2226.0
ARPC1B	669.0	4872.0
ARPC2	1357.0	2489.0
ARPC3	2873.0	1716.0
ARPC4	1698.0	-1177.0
ARPC5	2295.0	5164.0
ARSA	-3312.0	658.0
ARSB	-1001.0	3982.0
ART1	-5553.0	-4968.0
ASAH1	-3414.0	5351.0
ATAD3B	1907.0	-4848.5
ATF1	3129.0	3005.0
ATF2	3130.0	2882.0
ATG12	4060.0	1099.0
ATG5	1661.0	660.0
ATG7	-1364.0	900.0
ATOX1	646.0	-270.0
ATP11A	-1843.0	619.0
ATP11B	4841.0	197.0
ATP6AP2	2114.0	5391.0
ATP6V0A1	-3809.0	3329.0
ATP6V0A2	186.0	-1285.0
ATP6V0B	-3461.0	-2887.0
ATP6V0D1	-2256.0	2038.0
ATP6V0E1	1861.0	1404.0
ATP6V0E2	-1727.0	-2450.0
ATP6V1A	1633.0	2509.0
ATP6V1B2	2299.0	4785.0
ATP6V1C1	3521.0	4933.0
ATP6V1D	3269.0	-4077.0
ATP6V1E1	3913.0	495.0
ATP6V1F	-3562.0	-1774.0
ATP6V1G2	1570.0	144.0
ATP6V1H	-57.0	1416.0
ATP7A	1448.0	2206.0
ATP8A1	1830.0	-2343.0
B2M	-731.0	-1801.0
B4GALT1	-1314.0	287.0
BAIAP2	-641.0	5424.0
BCL10	4124.0	3809.0
BCL2	-4633.0	-3007.0
BCL2L1	-5181.0	430.0
BIRC2	3739.0	-1431.0
BIRC3	-4741.0	1787.0
BRI3	-3525.0	-3044.0
BRK1	2026.0	-636.0
BTRC	-1187.0	-2761.0
C1R	-813.0	-2544.0
C1S	-2427.0	-3402.0
C2	-558.0	-3222.0
C3	4311.0	-2705.0
C6orf120	1881.0	2505.0
C7	-1128.0	2548.0
CAB39	2485.0	4826.0
CALM1	-4464.0	1071.0
CAND1	3370.0	5245.0
CANT1	511.0	2850.0
CAP1	2590.0	3803.0
CAPN1	-5166.0	-3782.0
CAPZA2	-1777.0	-1888.0
CASP1	-1298.0	1115.0
CASP2	2946.0	-2821.0
CASP8	-1646.0	3398.0
CASP9	-3269.0	-3219.0
CAT	-4828.0	-4447.0
CCT2	3805.0	5006.0
CCT8	4149.0	3936.0
CD36	-582.0	-4709.0
CD44	837.0	5375.0
CD46	1543.0	-2023.0
CD47	-2184.0	997.0
CD55	220.0	-3197.0
CD59	1637.0	-3772.0
CD63	-3297.0	4795.0
CD81	-4675.0	59.0
CDC34	-2923.0	-3453.0
CDC42	3308.0	965.0
CDK13	4123.0	3295.0
CEP290	3352.0	-1031.0
CFH	-556.0	277.0
CFL1	-909.0	5151.0
CHUK	216.0	3591.0
CKAP4	-3818.0	5046.0
CLU	1629.0	2684.0
CMTM6	2331.0	4657.0
CNN2	-4870.0	2217.0
CNPY3	-3045.0	2799.0
COMMD3	246.0	-4206.0
COMMD9	385.0	2670.0
COPB1	3916.0	5120.0
COTL1	-1553.0	5385.0
CPNE3	1228.0	-837.0
CPPED1	-3625.0	-4751.0
CRCP	1806.0	-1063.0
CREB1	2179.0	-1920.0
CREBBP	1506.0	4134.0
CREG1	1430.0	-1378.0
CRISPLD2	-871.0	-892.0
CRK	2145.0	4206.0
CSNK2B	1917.0	-1746.0
CSTB	-3426.0	4472.0
CTNNB1	1714.0	2956.0
CTSA	-3537.0	-3391.0
CTSB	-1198.0	-1439.0
CTSC	2720.0	-35.0
CTSD	-4817.0	-2585.0
CTSH	-3465.0	4096.0
CTSK	2.0	2230.0
CTSS	-339.0	3969.0
CTSV	2209.0	1721.0
CTSZ	-3890.0	3780.0
CUL1	-3121.0	-833.0
CYB5R3	-5395.0	3844.0
CYBA	-633.0	2247.0
CYBB	-2550.0	3868.0
CYFIP2	-3775.0	-2981.0
CYLD	-1990.0	4116.0
CYSTM1	-1304.0	1546.0
DBNL	-2320.0	5161.0
DDOST	320.0	4978.0
DDX3X	4686.0	5191.0
DDX41	273.0	372.0
DDX58	1593.0	809.0
DEGS1	-2228.0	4156.0
DERA	3823.0	2342.0
DGAT1	-2804.0	-766.0
DHX36	3822.0	-1009.0
DHX58	-2934.0	3216.0
DHX9	4151.0	2848.0
DIAPH1	3282.0	4405.0
DNAJC13	1888.0	449.0
DNAJC3	1950.0	4619.0
DNAJC5	-2830.0	3712.0
DNASE1L1	-5205.0	-4988.0
DNM1	-747.0	1423.0
DNM2	-1149.0	218.0
DNM3	4865.0	1236.0
DOCK1	-226.0	2409.0
DOK3	-5498.0	1278.0
DPP7	-4199.0	3412.0
DSN1	2075.0	-665.0
DTX4	4372.0	-1688.0
DUSP3	-5149.0	-4856.0
DUSP4	-3613.0	786.0
DUSP6	-528.0	-3212.0
DUSP7	-3477.0	-3896.0
DYNC1H1	-1442.0	1264.0
DYNC1LI1	2883.0	981.0
DYNLL1	-1331.0	3935.0
DYNLT1	2579.0	2427.0
ECSIT	-2655.0	-4003.0
EEA1	1370.0	3693.0
EEF1A1	-2150.0	3461.0
EEF2	-2853.0	740.0
ELK1	-3862.0	1269.0
ELMO1	-2166.0	2524.0
ELMO2	-354.0	1439.0
ENPP4	-1280.0	-3522.0
EP300	3403.0	2309.0
ERP44	2150.0	1058.0
FABP5	-338.0	587.0
FADD	-571.0	3829.0
FAF2	3890.0	4157.0
FBXW11	4385.0	5178.0
FGL2	-1862.0	3337.0
FOS	1865.0	5350.0
FRK	194.0	2355.0
FTH1	-1890.0	-2807.0
FUCA1	111.0	1204.0
FUCA2	-2160.0	-2430.0
FYN	-2850.0	4537.0
GAA	-5001.0	-2492.0
GAB2	4053.0	2415.0
GALNS	-3960.0	5119.0
GCA	2461.0	-3509.0
GDI2	865.0	4995.0
GGH	3482.0	592.0
GHDC	-3542.0	-2146.0
GLA	3418.0	-1236.0
GLB1	-2244.0	2071.0
GM2A	-1169.0	1984.0
GNS	101.0	639.0
GOLGA7	1185.0	2154.0
GPI	-5210.0	-4750.0
GRB2	-4050.0	3027.0
GRN	-4029.0	2510.0
GSDMD	-2517.0	588.0
GSN	72.0	-78.0
GUSB	1923.0	4620.0
GYG1	-3875.0	4407.0
HEXB	753.0	1511.0
HGSNAT	-4600.0	349.0
HMGB1	-2199.0	-3939.0
HMOX2	-687.0	-3441.0
HRAS	-4545.0	-4872.0
HSP90AA1	3656.0	5525.0
HSP90AB1	-639.0	5203.0
HSP90B1	460.0	4768.0
HSPA1A	4887.0	5534.5
HSPA1B	4676.0	5534.5
HSPA8	3674.0	5419.0
HUWE1	-673.0	397.0
HVCN1	-2318.0	-3745.0
ICAM2	-1505.0	-2453.0
IDH1	1160.0	-4779.0
IFI16	-1127.0	5085.5
IFIH1	-204.0	-2805.0
IGF2R	-2030.0	2034.0
IKBKB	-4093.0	2980.0
ILF2	4835.0	3568.0
IMPDH1	-827.0	3626.0
IMPDH2	822.0	-801.0
IQGAP1	-415.0	4295.0
IRAK1	-4351.0	-1420.0
IRAK2	-4255.0	3504.0
IRAK3	95.0	1205.0
IRAK4	-569.0	3445.0
IRF3	-3061.0	-2463.0
IRF7	775.0	2624.0
ISG15	-3928.0	-331.0
IST1	3827.0	3890.0
ITCH	4319.0	2263.0
ITGAM	-2633.0	5000.0
ITGAV	-819.0	2947.0
ITGAX	-896.0	-49.0
ITGB2	-107.0	4082.0
ITPR1	4903.0	1106.0
ITPR2	1242.0	53.0
ITPR3	-3631.0	-2403.0
JUN	2469.0	5472.0
JUP	1723.0	4991.0
KCMF1	501.0	-106.0
KCNAB2	-3198.0	3369.0
KPNB1	3619.0	4744.0
KRAS	3546.0	5146.0
LAMP1	764.0	-3620.0
LAMP2	-2579.0	4194.0
LAMTOR1	-800.0	-4509.0
LAMTOR2	-1715.0	-4532.0
LAMTOR3	3134.0	781.0
LAT2	-1020.0	1710.0
LGALS3	1062.0	4689.0
LGMN	4834.0	651.0
LIMK1	-4857.0	3467.0
LPCAT1	-1659.0	2360.0
LRRFIP1	-4175.0	-3317.0
LTA4H	1584.0	2751.0
LYN	785.0	2842.0
MAGT1	1192.0	-616.0
MALT1	-2616.0	-3716.0
MAN2B1	-3000.0	564.0
MANBA	-1928.0	-2624.0
MAP2K1	-506.0	-3734.0
MAP2K3	-4716.0	3926.0
MAP2K4	8.0	1873.0
MAP2K6	1456.0	-4331.0
MAP2K7	794.0	-4191.0
MAP3K1	1124.0	-642.0
MAP3K7	2142.0	1585.0
MAP3K8	344.0	1263.0
MAPK1	1988.0	-969.0
MAPK10	-3504.0	-1276.0
MAPK11	-3385.0	1370.0
MAPK12	-5264.0	99.0
MAPK14	-1562.0	-2824.0
MAPK3	-1024.0	4464.0
MAPK7	-729.0	2102.0
MAPK8	457.0	1743.0
MAPK9	-3854.0	-738.0
MAPKAPK2	-2489.0	-1825.0
MAPKAPK3	-4795.0	1592.0
MASP1	-4224.0	298.0
MAVS	-4768.0	-4641.0
MEF2A	-5175.0	-1587.0
MEF2C	-4610.0	2307.0
METTL7A	-5605.0	-4947.0
MGST1	427.0	-2928.0
MIF	-2307.0	-3224.0
MLEC	-3173.0	317.0
MME	-3346.0	-1455.0
MOSPD2	3720.0	-1551.0
MVP	-4506.0	1795.0
MYD88	2726.0	2870.0
MYH2	-3080.0	-1826.0
MYH9	-1879.0	4997.0
MYO10	1381.0	2797.0
MYO1C	-4842.0	4663.0
MYO5A	-885.0	4252.0
MYO9B	-1901.0	4621.0
NBEAL2	-4727.0	1478.0
NCK1	3718.0	2059.0
NCKAP1	3563.0	5090.0
NCKIPSD	-2821.0	3136.0
NCSTN	-2504.0	-846.0
NDUFC2	34.0	-4249.0
NEU1	1863.0	2997.0
NF2	-1449.0	-3031.0
NFASC	-2394.0	3767.0
NFATC1	-5337.0	-3274.0
NFATC2	-3264.0	2685.0
NFATC3	-3321.0	1846.0
NFKB1	-4233.0	2228.0
NFKB2	-3926.0	2289.0
NFKBIA	-4263.0	1229.0
NFKBIB	4450.0	2806.0
NHLRC3	-3747.0	3010.0
NIT2	-1606.0	-413.0
NKIRAS1	4369.0	-4175.0
NKIRAS2	-1369.0	665.0
NLRC3	-2924.0	-1284.0
NLRC5	-4398.0	-1577.0
NLRX1	-4825.0	-3704.0
NOD1	-3886.0	-667.0
NOD2	-4402.0	2741.0
NOS1	-4260.0	-3419.0
NPC2	790.0	1192.0
NRAS	4354.0	1003.0
ORMDL3	893.0	3754.0
OSTF1	2228.0	-712.0
OTUD5	4179.0	2056.0
PADI2	-5625.0	-4412.0
PAFAH1B2	3709.0	5290.0
PAK1	-5419.0	-4706.0
PAK2	1525.0	5331.0
PANX1	1142.0	3665.0
PDAP1	-1236.0	-1152.0
PDPK1	3443.0	3947.0
PDXK	-4690.0	-936.0
PDZD11	1678.0	-2562.0
PELI1	4489.0	5252.0
PELI2	3371.0	1384.0
PELI3	-4396.0	2800.0
PFKL	-4966.0	4614.0
PGM1	-4270.0	-4828.0
PGM2	-561.0	4131.0
PGRMC1	-333.0	-191.0
PIK3C3	3439.0	-1596.0
PIK3CA	365.0	4218.0
PIK3CB	2760.0	5125.0
PIK3R1	2896.0	-813.0
PIK3R4	3839.0	-3124.0
PIN1	-3515.0	-3234.0
PKM	-4231.0	-3432.0
PLA2G6	-3913.0	-2025.0
PLAU	-548.0	595.0
PLAUR	-638.0	2110.0
PLCG1	-3955.0	-1787.0
PLD1	55.0	46.0
PLD2	-60.0	-498.0
PLD3	-5217.0	18.0
PLEKHO2	-717.0	3001.0
PNP	5019.5	4921.0
POLR1C	3643.0	3611.0
POLR1D	413.0	-1581.0
POLR2E	-667.0	148.0
POLR2H	-3927.0	2213.0
POLR2K	2480.0	-3599.0
POLR2L	-4314.0	-1126.0
POLR3A	4348.0	-1472.0
POLR3B	2547.0	-2035.0
POLR3C	4052.0	859.0
POLR3D	381.0	-435.0
POLR3E	1908.0	1839.0
POLR3F	4054.0	5048.0
POLR3G	1455.0	3939.0
POLR3GL	-1424.0	-4510.0
POLR3H	282.0	294.0
POLR3K	4716.0	-3380.0
PPIA	-4031.0	4207.0
PPIE	2144.0	-1849.0
PPP2CA	4482.0	1672.0
PPP2CB	2458.0	2352.0
PPP2R1A	-4013.0	-681.0
PPP2R1B	3028.0	3194.0
PPP2R5D	-3449.0	-620.0
PPP3CA	109.0	-1172.0
PPP3CB	-3435.0	-1839.0
PRCP	970.0	598.0
PRDX4	132.0	857.0
PRDX6	-3481.0	4983.0
PRKACA	-4691.0	-4303.0
PRKACB	-2659.0	-360.0
PRKCD	-4276.0	1141.0
PRKCE	-4307.0	-348.0
PRKCQ	-5095.0	-4724.0
PRKCSH	-268.0	367.0
PRKDC	2294.0	3813.0
PROS1	103.0	2992.0
PSAP	-2247.0	-4177.0
PSEN1	2070.0	3570.0
PSMA1	2820.0	4043.0
PSMA3	3434.0	-1035.0
PSMA4	769.0	-1962.0
PSMA6	2199.0	-1657.0
PSMA7	-2980.0	-1038.0
PSMB1	954.0	-1037.0
PSMB10	-1800.0	-831.0
PSMB2	618.0	-67.0
PSMB4	-235.0	-559.0
PSMB5	-4113.0	-2597.0
PSMB6	-793.0	-1795.0
PSMB7	-831.0	-2699.0
PSMB8	-675.0	-2510.0
PSMB9	-1611.0	-3558.0
PSMC1	449.0	1146.0
PSMC2	-1311.0	3386.0
PSMC3	-2439.0	-1846.0
PSMC4	2724.0	-205.0
PSMC5	1212.0	-1680.0
PSMC6	-2520.0	3114.0
PSMD1	2619.0	3210.0
PSMD10	-1227.0	361.0
PSMD11	995.0	5504.0
PSMD12	3831.0	-462.0
PSMD13	821.0	532.0
PSMD14	-635.0	3746.0
PSMD2	-713.0	741.0
PSMD3	-3343.0	-354.0
PSMD4	-214.0	968.0
PSMD5	1807.0	4479.0
PSMD6	3537.0	-3784.0
PSMD7	-2329.0	410.0
PSMD8	-3171.0	4292.0
PSMD9	4204.0	-3586.0
PSME1	-2771.0	-2861.0
PSME2	-4085.0	-41.0
PSME3	3333.0	491.0
PSME4	1960.0	2319.0
PSMF1	683.0	-1768.0
PTGES2	-2699.0	-3773.0
PTK2	-2497.0	2145.0
PTPN11	-1575.0	3105.0
PTPN4	-1408.0	5055.0
PTPN6	-931.0	4180.0
PTPRB	-4654.0	-1500.0
PTPRJ	391.0	4189.0
PTX3	-1790.0	-2063.0
PYCARD	-2810.0	3218.0
PYGB	-4498.0	2607.0
PYGL	-3546.0	2519.0
QPCT	250.0	4753.0
QSOX1	2045.0	3683.0
RAB10	-2646.0	-3833.0
RAB14	2341.0	-431.0
RAB18	4588.0	-2104.0
RAB24	-1792.0	-4802.0
RAB27A	169.0	-190.0
RAB31	-547.0	4317.0
RAB3A	75.0	-4870.0
RAB3D	3527.0	2881.0
RAB5B	584.0	-3999.0
RAB5C	2317.0	3682.0
RAB7A	-383.0	3232.0
RAC1	2525.0	-240.0
RAC2	41.0	4138.0
RAF1	1712.0	-1201.0
RAP1A	-689.0	3944.0
RAP1B	4479.0	5079.0
RAP2B	3971.0	4719.0
RAP2C	-983.0	-776.0
RASGRP2	-2556.0	-4004.0
RELA	1783.0	4454.0
RELB	-2305.0	2910.0
RHOA	539.0	4106.0
RHOG	-1207.0	5167.0
RIPK1	325.0	189.0
RIPK2	3609.0	4684.0
RNASET2	-4153.0	-4148.0
RNF125	3620.0	-570.0
RNF135	-3677.0	1588.0
RNF216	-4323.0	2967.0
ROCK1	4876.0	3865.0
RPS27A	783.0	-2165.0
RPS6KA1	-1481.0	-1813.0
RPS6KA2	-4748.0	-4135.0
RPS6KA3	952.0	2296.0
RPS6KA5	51.0	-4805.0
S100A1	-4789.0	-4016.0
S100A11	-3518.0	4873.0
SCAMP1	-549.0	1425.0
SDCBP	4377.0	4250.0
SERPINB1	1882.0	5473.0
SERPINB6	-5411.0	4298.0
SERPING1	78.0	-151.0
SHC1	3976.0	4815.0
SIGIRR	-452.0	-2169.0
SIKE1	-73.0	3034.0
SIRPA	-5627.0	4799.0
SKP1	2028.0	-1286.0
SLC15A4	-527.0	308.0
SLC2A3	5004.0	2223.5
SLC44A2	-5438.0	-4047.0
SNAP23	372.0	2500.0
SNAP29	-2698.0	2654.0
SOCS1	199.0	3983.0
SOS1	-1962.0	2326.0
SPTAN1	-2425.0	412.0
SRC	-3910.0	3763.0
SRP14	2888.0	-3550.0
STAT6	-5317.0	-88.0
STK10	-3246.0	1876.0
STK11IP	-451.0	-2225.0
STOM	2424.0	4910.0
SUGT1	3140.0	-4993.0
SURF4	1238.0	4861.0
SVIP	3363.0	-4374.0
SYNGR1	-4900.0	-4120.0
TAB1	-4874.0	-4377.0
TAB2	2791.0	3798.0
TAB3	2116.0	5258.0
TANK	3655.0	3759.0
TAX1BP1	3222.0	-87.0
TBK1	673.0	2827.0
TCIRG1	-3600.0	4574.0
TEC	3728.0	3350.0
TICAM1	1624.0	1665.0
TIFA	-1142.0	-448.0
TIMP2	-1886.0	1226.0
TIRAP	-2943.0	242.0
TLR3	-310.0	-1745.0
TLR4	1065.0	4797.0
TLR5	-3234.0	-1217.0
TLR6	888.0	2027.0
TMBIM1	-4812.0	4333.0
TMC6	-4677.0	1043.0
TMEM30A	2855.0	-2091.0
TMEM63A	-4829.0	3044.0
TNFAIP3	-5203.0	3469.0
TNFAIP6	1870.0	4169.0
TNFRSF1B	-874.0	4531.0
TNIP2	-1370.0	4330.0
TOLLIP	-256.0	1819.0
TOM1	-5386.0	-2820.0
TRAF2	-1546.0	2643.0
TRAF3	-3815.0	4367.0
TRAF6	3468.0	4662.0
TRAPPC1	368.0	-3150.0
TRIM21	2960.0	-2527.0
TRIM25	-3243.0	-1502.0
TRIM32	1027.0	5067.0
TRIM56	-3368.0	-2264.0
TSPAN14	-4941.0	-2779.0
TUBB	-3118.0	5321.0
TUBB4B	430.0	4642.0
TXN	1855.0	4827.0
UBA3	3512.0	3512.0
UBA7	-1671.0	-2885.0
UBC	2672.0	3877.0
UBE2D1	-1588.0	-4657.0
UBE2D2	-1986.0	1804.0
UBE2D3	1424.0	5192.0
UBE2K	1393.0	1348.0
UBE2L6	-3548.0	3305.0
UBE2M	1247.0	-854.0
UBE2N	2545.0	4245.0
UBR4	2440.0	758.0
VAMP8	-2728.0	-4982.0
VAPA	2838.0	2825.0
VAT1	-4095.0	4499.0
VAV2	-4959.0	2847.0
VAV3	187.0	-276.0
VCL	-4538.0	5383.0
VRK3	464.0	3294.0
WASF2	-4656.0	3026.0
WASF3	-1015.0	1293.0
WASL	2683.0	4511.0
WIPF1	-2552.0	2457.0
WIPF2	3299.0	-608.0
WIPF3	-5107.0	-4936.0
XRCC5	4010.0	1456.0
XRCC6	3225.0	-2097.0
YES1	-176.0	-836.0
YPEL5	4366.0	4902.0

---

---

Hemostasis

Hemostasis

metric	value
setSize	349
pMANOVA	1.51e-10
p.adjustMANOVA	4.65e-09
s.dist	0.192
s.human	-0.141
s.mouse	0.13
p.human	7.12e-06
p.mouse	3.65e-05

Top 20 genes

Gene	human	mouse
SIRPA	-5627	4799.0
BCAR1	-4922	5371.0
ITGA5	-4752	5495.0
EHD1	-4458	5480.0
VCL	-4538	5383.0
SERPINB6	-5411	4298.0
ANXA2	-4123	5407.0
ENDOD1	-4813	4455.0
SH2B3	-4833	4233.0
P2RX5	-4736	4024.5
KIF2A	-4390	4073.0
MAFF	-3749	4661.0
PDPN	-3304	5189.0
CSK	-3610	4728.0
PPIA	-4031	4207.0
DOCK11	-4738	3576.0
MAFG	-4198	3817.0
CD63	-3297	4795.0
CD109	-3329	4706.0
SRI	-4069	3732.0

Click HERE to show all gene set members

All member genes

	human	mouse
AAMP	2657	2106.0
ABCC4	1368	-1784.0
ABHD12	-778	-482.0
ABHD6	-2808	-530.0
ABL1	-4533	1377.0
ACTN1	-676	4422.0
ACTN2	-3104	-1086.0
ACTN4	1805	4592.0
ADRA2A	-4661	-686.0
AK3	-3164	-5058.0
AKAP1	-5093	-4966.0
AKAP10	3696	-2676.0
AKT1	-4954	1242.0
ALDOA	-5575	-3960.0
ANGPT1	-853	-3559.0
ANXA2	-4123	5407.0
ANXA5	2401	4868.0
APLP2	1316	-583.0
APOOL	-69	-4059.0
APP	-2792	154.0
ARRB1	-3133	2633.0
ARRB2	-1089	3740.0
ATP1B1	2576	-3831.0
ATP1B3	-598	2812.0
ATP2A1	-5479	-4435.0
ATP2A2	-2976	2104.0
ATP2A3	-4467	1381.0
ATP2B1	2034	3586.0
ATP2B3	-4422	-4436.0
ATP2B4	-2762	2239.0
BCAR1	-4922	5371.0
BRPF3	3668	4607.0
BSG	-2248	-3662.0
C1QBP	3798	-2891.0
CABLES1	-4484	662.0
CABLES2	-4326	2233.0
CALM1	-4464	1071.0
CALU	3246	5382.0
CAP1	2590	3803.0
CAPZA2	-1777	-1888.0
CAPZB	-3165	-2404.0
CAV1	-646	-1312.0
CBX5	1538	1494.0
CD109	-3329	4706.0
CD36	-582	-4709.0
CD44	837	5375.0
CD47	-2184	997.0
CD63	-3297	4795.0
CD9	2203	3954.0
CD99L2	-4169	1420.0
CDC37L1	-111	-1843.0
CDC42	3308	965.0
CDK2	849	2902.0
CDK5	-1007	-2874.0
CFL1	-909	5151.0
CHID1	-2865	663.0
CLEC3B	-629	-2937.0
CLU	1629	2684.0
CRK	2145	4206.0
CSK	-3610	4728.0
CYB5R1	-4864	-4192.0
DAGLA	-5158	-1202.0
DAGLB	3782	-3217.0
DGKA	-2368	-2473.0
DGKB	-4489	-1599.0
DGKD	-5077	2121.0
DGKE	1911	-4489.0
DGKH	3337	3991.0
DGKQ	-2188	-3043.0
DGKZ	-5581	-3517.0
DOCK1	-226	2409.0
DOCK10	4096	2815.0
DOCK11	-4738	3576.0
DOCK4	1844	-3322.0
DOCK5	-1286	2817.0
DOCK6	-1306	633.0
DOCK7	4461	2938.0
DOCK8	-3782	2492.0
DOCK9	-2258	-4138.0
ECM1	-3535	2310.0
EGF	-4568	-4926.0
EHD1	-4458	5480.0
EHD2	-5214	-1433.0
EHD3	-3462	3135.0
ENDOD1	-4813	4455.0
F11R	-2302	-3195.0
F13A1	-2059	4132.0
F2R	1667	2871.0
F3	-1733	2873.0
F8	-941	-1367.0
FAM3C	-1909	2397.0
FERMT3	-2875	3650.0
FLNA	-3248	4449.0
FN1	35	4381.0
FYN	-2850	4537.0
GAS6	-5013	-4091.0
GLG1	-2906	2989.0
GNA11	-1689	2150.0
GNA12	-3059	4306.0
GNA13	-209	5323.0
GNAI1	183	1373.0
GNAI2	800	2142.0
GNAI3	4221	4647.0
GNAQ	4906	4533.0
GNAS	-3163	-1742.0
GNB1	177	5374.0
GNB2	-3870	1232.0
GNB3	-3272	-676.0
GNB4	-3491	1634.0
GNB5	879	-2818.0
GNG11	4695	-4457.0
GNG12	612	604.0
GNG2	802	-2139.0
GNG5	415	-3220.0
GNG7	-2742	-4220.0
GPC1	-5269	-1574.0
GRB14	-1485	-4613.0
GRB2	-4050	3027.0
GTPBP2	-1376	-4735.0
GUCY1B3	4506	-4823.0
GYPC	-3255	-4235.0
HABP4	-4207	-83.0
HDAC2	4386	-579.0
HMG20B	704	-3309.0
HRAS	-4545	-4872.0
HSPA5	2574	5400.0
IGF2	-4754	2227.0
INPP5D	-2433	4627.0
IRF1	-1565	-1908.0
IRF2	-3387	-1585.0
ISLR	-2846	1221.0
ITGA1	1757	-1535.0
ITGA10	-1878	25.0
ITGA3	-5514	2747.0
ITGA4	-2878	-2673.0
ITGA5	-4752	5495.0
ITGA6	-1002	-4343.0
ITGAM	-2633	5000.0
ITGAV	-819	2947.0
ITGAX	-896	-49.0
ITGB1	956	5174.0
ITGB2	-107	4082.0
ITGB3	-488	5180.0
ITPK1	-2911	3927.0
ITPR1	4903	1106.0
ITPR2	1242	53.0
ITPR3	-3631	-2403.0
JAK2	-2569	-2171.0
JAM2	-5328	-4015.0
JAM3	1283	-1980.0
JMJD1C	312	5237.0
KCNMA1	-2841	928.0
KDM1A	249	5433.0
KIF11	2319	3552.0
KIF13B	-1749	477.0
KIF16B	3552	-5102.0
KIF18A	3832	2448.0
KIF1A	905	1189.0
KIF1B	1513	1550.0
KIF1C	-5118	-3146.0
KIF21A	4624	-1384.0
KIF21B	-4761	3137.0
KIF23	1216	2656.0
KIF26B	-3147	-2389.0
KIF2A	-4390	4073.0
KIF3A	4718	3190.0
KIF3B	3571	3912.0
KIF3C	-3766	-1414.0
KIF5A	4430	584.0
KIF5B	838	4559.0
KIF5C	4658	2757.0
KIFAP3	-1339	-4044.0
KIFC2	-4370	-4717.0
KLC1	-3922	2207.0
KLC2	-1732	-487.0
KLC4	-3559	-2759.0
KRAS	3546	5146.0
L1CAM	945	-243.0
LAMP2	-2579	4194.0
LGALS3BP	-4500	-2320.0
LHFPL2	161	3112.0
LYN	785	2842.0
MAFF	-3749	4661.0
MAFG	-4198	3817.0
MAFK	-374	5337.0
MAGED2	-4316	-446.0
MANF	2108	5398.0
MAPK1	1988	-969.0
MAPK14	-1562	-2824.0
MAPK3	-1024	4464.0
MERTK	-1975	2951.0
MFN1	4339	-4981.0
MFN2	-1456	-4673.0
MGLL	-5374	-5059.0
MICAL1	-4962	1166.0
MIF	-2307	-3224.0
NHLRC2	2062	742.0
NOS1	-4260	-3419.0
NRAS	4354	1003.0
OLA1	1860	-1986.0
ORAI2	936	56.0
P2RX4	-1108	2922.0
P2RX5	-4736	4024.5
P2RX6	-5567	-3095.0
PAFAH2	-3734	-3202.0
PCDH7	3641	4970.0
PCYOX1L	201	-2134.0
PDE10A	2072	2109.0
PDE1A	2411	-405.0
PDE5A	-78	903.0
PDGFA	-4328	-2495.0
PDGFB	-606	1041.0
PDPK1	3443	3947.0
PDPN	-3304	5189.0
PFN1	467	-2704.0
PHACTR2	3632	-2714.0
PHF21A	-4739	-533.0
PICK1	-881	-4487.0
PIK3CA	365	4218.0
PIK3CB	2760	5125.0
PIK3R1	2896	-813.0
PIK3R3	3188	3545.0
PLA2G4A	603	4806.0
PLAT	1414	4193.0
PLAU	-548	595.0
PLAUR	-638	2110.0
PLCG1	-3955	-1787.0
PLEK	-3003	3248.0
PPIA	-4031	4207.0
PPIL2	-4421	-2298.0
PPP2CA	4482	1672.0
PPP2CB	2458	2352.0
PPP2R1A	-4013	-681.0
PPP2R1B	3028	3194.0
PPP2R5A	4590	3889.0
PPP2R5B	-1524	-765.0
PPP2R5C	-2508	-293.0
PPP2R5D	-3449	-620.0
PPP2R5E	4644	2107.0
PRCP	970	598.0
PRKACA	-4691	-4303.0
PRKACB	-2659	-360.0
PRKAR1A	-3106	203.0
PRKAR1B	-2442	3659.0
PRKAR2A	-2664	1823.0
PRKAR2B	3460	1006.0
PRKCA	-2938	1125.0
PRKCD	-4276	1141.0
PRKCE	-4307	-348.0
PRKCQ	-5095	-4724.0
PRKG1	1401	5353.0
PROCR	22	-3863.0
PROS1	103	2992.0
PSAP	-2247	-4177.0
PTGIR	-370	3747.0
PTK2	-2497	2145.0
PTPN1	1531	4935.0
PTPN11	-1575	3105.0
PTPN6	-931	4180.0
QSOX1	2045	3683.0
RAB27B	2206	-668.0
RAB5A	2109	4613.0
RAC1	2525	-240.0
RAC2	41	4138.0
RACGAP1	4239	3807.0
RAF1	1712	-1201.0
RAP1A	-689	3944.0
RAP1B	4479	5079.0
RAPGEF3	108	-2916.0
RAPGEF4	4622	4334.0
RARRES2	-3551	-1489.0
RASGRP2	-2556	-4004.0
RCOR1	4776	3876.0
RHOA	539	4106.0
RHOB	4609	4443.0
RHOG	-1207	5167.0
S100A10	-1995	5394.0
SCCPDH	-2874	-4578.0
SDC1	-2046	1023.0
SDC2	1756	4994.0
SDC3	-4619	2991.0
SDC4	-2393	5425.0
SELPLG	-4620	616.0
SERPINB6	-5411	4298.0
SERPINB8	2357	4583.0
SERPINE1	-211	5469.0
SERPINE2	687	-2334.0
SERPING1	78	-151.0
SH2B1	-3841	1127.0
SH2B2	-4553	2511.0
SH2B3	-4833	4233.0
SHC1	3976	4815.0
SIN3A	3397	2893.0
SIRPA	-5627	4799.0
SLC16A1	-987	2280.0
SLC16A3	-4751	-4193.0
SLC3A2	-656	2824.0
SLC7A5	-2463	5030.0
SLC7A6	-5241	1161.0
SLC7A7	-3748	713.0
SLC7A8	-1965	2737.0
SLC8A1	754	-1425.0
SLC8A3	-5477	-1832.0
SOD1	157	-2728.0
SOS1	-1962	2326.0
SPARC	-2672	1436.0
SRC	-3910	3763.0
SRGN	1742	-334.0
SRI	-4069	3732.0
STIM1	-3417	-3701.0
STX4	-2347	-2961.0
STXBP3	3943	-2830.0
SYTL4	1697	27.0
TAGLN2	-25	5218.0
TEK	3580	-1484.0
TEX264	-5025	-789.0
TFPI	894	243.0
TGFB1	-3111	4516.0
TGFB2	4602	2406.0
TGFB3	-5326	1062.0
THBD	-1571	4514.0
THBS1	762	5034.0
THPO	-2147	-3825.0
TIMP1	-1317	5467.0
TIMP3	1582	-1661.0
TLN1	-3918	3071.0
TMX3	-1118	-718.0
TNFRSF10A	-3936	485.5
TNFRSF10B	-1612	485.5
TNFRSF10D	-3227	485.5
TOR4A	2444	-440.0
TP53	575	3128.0
TSPAN7	-5133	-2559.0
TTN	3968	-2380.0
TUBA4A	-5342	240.0
VAV2	-4959	2847.0
VAV3	187	-276.0
VCL	-4538	5383.0
VEGFA	-4571	-5070.0
VEGFB	-4617	-3478.0
VEGFC	1169	2268.0
VPS45	-4193	-57.0
VTI1B	609	-1531.0
VWF	-779	1730.0
WDR1	-313	5441.0
WEE1	-4561	3159.0
YES1	-176	-836.0
YWHAZ	2019	4919.0
ZFPM1	71	-424.0

---

---

RNA Polymerase II Pre-transcription Events

RNA Polymerase II Pre-transcription Events

metric	value
setSize	69
pMANOVA	2.02e-10
p.adjustMANOVA	6.09e-09
s.dist	0.498
s.human	0.432
s.mouse	0.247
p.human	5.54e-10
p.mouse	0.000405

Top 20 genes

Gene	human	mouse
TAF4B	4967	5489
CTR9	4954	5471
SUPT6H	4807	5334
TAF7	4717	5281
GTF2B	4276	5493
EAF1	4531	5165
GTF2F1	4999	4439
POLR2A	3861	5366
GTF2F2	4067	5047
GTF2A1	4730	4204
TAF3	4294	4087
SUPT16H	3885	4417
AFF4	3610	4555
TAF2	4591	3536
MLLT3	3202	4762
TAF12	3100	3716
CTDP1	2071	4946
CDC73	2659	3408
IWS1	2510	3155
TAF13	4749	1646

Click HERE to show all gene set members

All member genes

	human	mouse
AFF4	3610	4555.0
CCNH	3825	-1939.0
CCNK	3139	-346.0
CCNT1	4896	309.0
CCNT2	4381	-4634.0
CDC73	2659	3408.0
CDK7	1571	326.0
CDK9	-1348	4755.0
CTDP1	2071	4946.0
CTR9	4954	5471.0
EAF1	4531	5165.0
ELL	-3990	3539.0
ERCC2	824	4319.0
ERCC3	473	3200.0
GTF2A1	4730	4204.0
GTF2A2	4648	-2956.0
GTF2B	4276	5493.0
GTF2E1	2188	896.0
GTF2E2	2041	-136.0
GTF2F1	4999	4439.0
GTF2F2	4067	5047.0
GTF2H1	3886	647.0
GTF2H2	4419	-2426.5
GTF2H3	-1925	-664.0
GTF2H5	-878	-3245.0
IWS1	2510	3155.0
LEO1	2784	-714.0
MLLT1	472	3521.0
MLLT3	3202	4762.0
MNAT1	830	-3106.0
NCBP1	-1736	4720.0
NCBP2	4188	-2519.0
NELFA	356	3429.0
NELFB	-1196	2017.0
NELFCD	1896	-2826.0
NELFE	-2178	3913.0
PAF1	2516	-2851.0
POLR2A	3861	5366.0
POLR2B	4509	-3401.0
POLR2C	4529	-4002.0
POLR2D	1669	3230.0
POLR2E	-667	148.0
POLR2G	89	4349.0
POLR2H	-3927	2213.0
POLR2I	-154	-2504.0
POLR2K	2480	-3599.0
POLR2L	-4314	-1126.0
RTF1	-2993	-2890.0
SSRP1	1755	1765.0
SUPT16H	3885	4417.0
SUPT4H1	3648	-1692.0
SUPT5H	1321	4377.0
SUPT6H	4807	5334.0
TAF1	1708	4363.0
TAF10	-273	547.0
TAF11	2962	-1678.0
TAF12	3100	3716.0
TAF13	4749	1646.0
TAF2	4591	3536.0
TAF3	4294	4087.0
TAF4	-1340	4027.0
TAF4B	4967	5489.0
TAF5	4309	1473.0
TAF6	-912	-885.0
TAF7	4717	5281.0
TAF9B	1874	-618.0
TBP	1137	3931.0
TCEA1	4037	163.0
WDR61	-1148	-234.0

---

---

Nervous system development

Nervous system development

metric	value
setSize	395
pMANOVA	4.08e-10
p.adjustMANOVA	1.2e-08
s.dist	0.177
s.human	-0.117
s.mouse	0.132
p.human	7.65e-05
p.mouse	7.97e-06

Top 20 genes

Gene	human	mouse
ST8SIA2	-5423	5201
ARHGAP35	-4960	5279
ITGA5	-4752	5495
RHOC	-4944	4844
NAB2	-5323	4380
PLXNA2	-5392	4161
SREBF2	-4703	4606
GDNF	-4043	5263
MSN	-3907	4981
ITGA9	-5247	3691
EGR2	-3746	5163
SCN5A	-5309	3639
CAP2	-5055	3553
PLXNA3	-5112	3454
DAG1	-5236	3304
NCAM1	-3954	4316
DPYSL5	-4934	3416
LIMK1	-4857	3467
ACTG1	-3075	5370
CXCL12	-4998	3271

Click HERE to show all gene set members

All member genes

	human	mouse
ABL1	-4533	1377
ABL2	4315	5380
ABLIM1	-4649	3280
ABLIM2	-5452	-2840
ABLIM3	-5094	-5010
ACTB	940	5427
ACTG1	-3075	5370
ACTR2	3547	5008
ACTR3	1376	5496
ADAM10	-1509	1096
AGAP2	-3629	2640
AGRN	-4903	783
ALCAM	3531	4456
ANK1	-5583	-4259
ANK2	-4297	-3995
ANK3	1331	-4094
AP2A1	-3632	-3002
AP2A2	-1058	5459
AP2B1	-1157	4733
AP2M1	-2746	1678
AP2S1	1777	-582
APH1A	204	-3096
APH1B	3428	1940
ARHGAP35	-4960	5279
ARHGAP39	-3062	2351
ARHGEF11	-1199	2030
ARHGEF12	2630	5108
ARHGEF28	-2642	1825
ARHGEF7	-3605	3212
ARPC1A	-120	2226
ARPC1B	669	4872
ARPC2	1357	2489
ARPC3	2873	1716
ARPC4	1698	-1177
ARPC5	2295	5164
CACNA1C	-762	1596
CACNA1H	-5590	-3891
CACNA1S	-5579	-469
CACNB1	-5285	-4156
CACNB3	149	260
CAP1	2590	3803
CAP2	-5055	3553
CASC3	9	2673
CDC42	3308	965
CDK5	-1007	-2874
CFL1	-909	5151
CLASP1	-3713	3198
CLASP2	2507	2478
CLTA	1218	-119
CLTB	-4579	2521
CLTC	2268	2273
CNTNAP1	-760	-157
COL4A1	-4755	1270
COL4A2	-5035	827
COL4A3	-3831	-4180
COL4A4	-3022	-3438
COL4A5	-4320	-2713
COL6A1	-1945	2783
COL6A2	-1836	2972
COL6A3	-119	3607
COL6A6	-2138	-1882
CREB1	2179	-1920
CSNK2A1	1796	-2551
CSNK2A2	2123	2667
CSNK2B	1917	-1746
CUL2	4097	-3279
CXCL12	-4998	3271
CYP51A1	-1716	5305
DAG1	-5236	3304
DLG1	-52	2473
DLG3	-1567	-728
DLG4	-1594	1830
DNM1	-747	1423
DNM2	-1149	218
DNM3	4865	1236
DOCK1	-226	2409
DOK1	-1380	-1735
DOK4	2391	-357
DOK5	-3981	510
DPYSL2	-572	4710
DPYSL3	-801	4668
DPYSL5	-4934	3416
DRP2	-4004	1540
EFNB1	-2053	3672
EFNB2	4782	1586
EFNB3	-577	1069
EGFR	424	2978
EGR2	-3746	5163
EIF4A3	4491	2615
EIF4G1	-2988	-962
ENAH	4332	5533
EPHA2	-3029	28
EPHA3	1472	512
EPHA4	-3528	3775
EPHA7	2741	2097
EPHB1	-3669	280
EPHB2	-3231	4018
EPHB3	-5580	1852
EPHB4	606	3179
EPHB6	-1676	-186
ERBB2	-5511	494
ETF1	3946	5448
EVL	-3566	-1001
EZR	-2209	5155
FARP2	-1333	-2454
FAU	2272	2649
FES	559	2496
FGFR1	-1499	-1279
FLRT3	4144	4853
FRS2	4678	3571
FYN	-2850	4537
GAB1	-1853	-1642
GAB2	4053	2415
GDNF	-4043	5263
GFRA1	-4438	-426
GIT1	-4208	1849
GPC1	-5269	-1574
GRB10	-1615	3264
GRB2	-4050	3027
GSK3B	897	4692
GSPT1	1495	2169
HDAC2	4386	-579
HFE2	-5332	-4625
HMGCR	971	4993
HRAS	-4545	-4872
HSP90AA1	3656	5525
HSP90AB1	-639	5203
HSPA8	3674	5419
IRS2	3384	2249
ITGA1	1757	-1535
ITGA10	-1878	25
ITGA5	-4752	5495
ITGA9	-5247	3691
ITGAV	-819	2947
ITGB1	956	5174
ITGB3	-488	5180
ITSN1	524	-2768
KALRN	-5340	-990
KRAS	3546	5146
L1CAM	945	-243
LAMA2	-3799	1005
LAMB1	-457	829
LAMC1	-3224	3688
LDB1	-5369	-3841
LIMK1	-4857	3467
LIMK2	-5357	-3001
LYN	785	2842
LYPLA2	-3796	-1812
MAGOH	4561	555
MAGOHB	2239	-1880
MAP2K1	-506	-3734
MAP2K2	-3813	-2235
MAPK1	1988	-969
MAPK11	-3385	1370
MAPK12	-5264	99
MAPK14	-1562	-2824
MAPK3	-1024	4464
MAPK7	-729	2102
MAPK8	457	1743
MBP	-2415	-1118
MET	-3529	4440
MMP2	-692	-606
MSN	-3907	4981
MYH10	50	5272
MYH14	-3853	-3524
MYH9	-1879	4997
MYL12A	84	5497
MYL12B	1563	594
MYL6	-3628	1353
MYL9	-4777	-1049
MYO10	1381	2797
MYO9B	-1901	4621
NAB1	-3099	2676
NAB2	-5323	4380
NCAM1	-3954	4316
NCBP1	-1736	4720
NCBP2	4188	-2519
NCK1	3718	2059
NCK2	-953	-4234
NCSTN	-2504	-846
NEO1	-1978	4743
NFASC	-2394	3767
NRAS	4354	1003
NRP1	-112	-3592
NRP2	2152	-1368
NTN1	-3499	509
NTN4	-1261	-2609
NUMB	2961	3921
PAK1	-5419	-4706
PAK2	1525	5331
PAK4	-1756	4763
PDLIM7	-5046	431
PFN1	467	-2704
PFN2	-4209	-2786
PIK3CA	365	4218
PIK3CB	2760	5125
PIK3CD	-4322	-2306
PIK3R1	2896	-813
PIK3R3	3188	3545
PIP5K1C	-1917	2945
PITPNA	-2450	-1450
PLCG1	-3955	-1787
PLXNA1	-4487	2733
PLXNA2	-5392	4161
PLXNA3	-5112	3454
PLXNA4	-319	1224
PLXNB1	-5451	-185
PLXNB3	-4041	-2921
PLXNC1	3270	-876
PLXND1	-4476	-1332
PMP22	-1291	940
PPP3CB	-3435	-1839
PRKACA	-4691	-4303
PRKACB	-2659	-360
PRKAR2A	-2664	1823
PRKCA	-2938	1125
PRKCQ	-5095	-4724
PRNP	2908	5455
PRX	-2568	288
PSEN1	2070	3570
PSEN2	-5371	-3111
PSENEN	-2638	-2344
PSMA1	2820	4043
PSMA3	3434	-1035
PSMA4	769	-1962
PSMA6	2199	-1657
PSMA7	-2980	-1038
PSMB1	954	-1037
PSMB10	-1800	-831
PSMB2	618	-67
PSMB4	-235	-559
PSMB5	-4113	-2597
PSMB6	-793	-1795
PSMB7	-831	-2699
PSMB8	-675	-2510
PSMB9	-1611	-3558
PSMC1	449	1146
PSMC2	-1311	3386
PSMC3	-2439	-1846
PSMC4	2724	-205
PSMC5	1212	-1680
PSMC6	-2520	3114
PSMD1	2619	3210
PSMD10	-1227	361
PSMD11	995	5504
PSMD12	3831	-462
PSMD13	821	532
PSMD14	-635	3746
PSMD2	-713	741
PSMD3	-3343	-354
PSMD4	-214	968
PSMD5	1807	4479
PSMD6	3537	-3784
PSMD7	-2329	410
PSMD8	-3171	4292
PSMD9	4204	-3586
PSME1	-2771	-2861
PSME2	-4085	-41
PSME3	3333	491
PSME4	1960	2319
PSMF1	683	-1768
PTK2	-2497	2145
PTPN11	-1575	3105
PTPRA	-402	3484
RAC1	2525	-240
RANBP9	4005	2691
RAP1GAP	-894	-1740
RASA1	-612	2537
RBX1	-733	-2400
RDX	-562	-1239
RELN	3729	2195
RGMA	-661	2453
RGMB	-413	1552
RHOA	539	4106
RHOB	4609	4443
RHOC	-4944	4844
RND1	3883	5464
RNPS1	681	-2204
ROBO1	3700	1277
ROBO2	-3259	-2350
ROCK1	4876	3865
ROCK2	2205	1929
RPL10	-3902	3923
RPL11	-2249	-1971
RPL14	433	-875
RPL18	-1782	448
RPL18A	-2969	-320
RPL19	-502	-1379
RPL22	1231	-3446
RPL22L1	3380	2374
RPL23	-115	-2882
RPL26	1047	696
RPL28	-391	-1891
RPL3	-786	5412
RPL30	286	-3056
RPL31	-595	2894
RPL32	-367	-950
RPL34	1447	-1314
RPL35A	812	-1471
RPL36A	1261	-1408
RPL37	-715	-1311
RPL37A	-1043	554
RPL38	231	-953
RPL3L	-5212	-4614
RPL4	-522	-571
RPL5	1206	3360
RPL7	1440	-1894
RPL8	-2775	-928
RPLP2	-2469	-3389
RPS11	-1582	-458
RPS12	-318	1501
RPS13	1131	-1994
RPS14	-1412	122
RPS15	-1799	-1082
RPS15A	-704	-237
RPS16	-1828	2010
RPS18	-974	-1404
RPS19	-2045	-882
RPS20	-1844	1712
RPS21	-1536	-2810
RPS23	-68	-749
RPS24	256	-1505
RPS26	-282	-1421
RPS27A	783	-2165
RPS27L	-616	-69
RPS29	-1140	-1275
RPS3	-544	116
RPS4X	83	97
RPS5	-1577	935
RPS6	-245	1237
RPS6KA1	-1481	-1813
RPS6KA2	-4748	-4135
RPS6KA3	952	2296
RPS6KA4	-1201	1611
RPS6KA5	51	-4805
RPS8	-1593	-1231
RPS9	-1107	-2477
RRAS	-4504	1910
SCN1B	-4899	-3023
SCN2A	544	1112
SCN2B	-4268	-3399
SCN3A	2439	4272
SCN3B	-3892	3499
SCN4A	-5601	-3596
SCN5A	-5309	3639
SDC2	1756	4994
SDCBP	4377	4250
SEMA3A	2682	3013
SEMA4A	796	892
SEMA4D	-5491	-921
SEMA5A	485	-760
SEMA6A	3579	-3855
SEMA6D	-3707	1044
SEMA7A	-768	4854
SH3KBP1	1014	-4274
SHANK3	-2640	-1410
SHC1	3976	4815
SIAH1	5006	1241
SIAH2	-1998	5492
SLIT1	-2284	2442
SLIT3	-271	2322
SMARCA4	-3874	863
SOS1	-1962	2326
SOS2	-563	-2646
SPTAN1	-2425	412
SPTB	-5499	1118
SPTBN1	-2919	-1221
SRC	-3910	3763
SREBF2	-4703	4606
SRGAP1	938	2617
SRGAP3	-3043	3924
ST8SIA2	-5423	5201
ST8SIA4	3236	-2118
TEAD1	-4292	2647
TIAM1	2024	-347
TLN1	-3918	3071
TRIO	1163	-378
TRPC1	1744	1215
UBC	2672	3877
UNC5A	-775	2527
UNC5B	-1122	-305
UPF2	3566	-2231
UPF3A	-2545	729
UPF3B	1586	-4490
USP33	2501	475
UTRN	-3639	-373
VASP	-142	2533
VAV2	-4959	2847
VAV3	187	-276
VLDLR	-4564	-4868
WASL	2683	4511
WWTR1	-2503	3401
YAP1	-476	5038
YES1	-176	-836
ZSWIM8	-1026	1820

---

---

Metabolism of non-coding RNA

Metabolism of non-coding RNA

metric	value
setSize	45
pMANOVA	4.91e-10
p.adjustMANOVA	1.38e-08
s.dist	0.588
s.human	0.556
s.mouse	0.192
p.human	1.1e-10
p.mouse	0.0258

Top 20 genes

Gene	human	mouse
NUP98	4235	5486.0
NUP54	4508	4751.0
NUP153	4762	4031.0
NUP205	4438	3917.0
RAE1	4471	3078.0
TGS1	4576	2855.0
NUP155	4306	2897.0
NUP35	4571	2515.0
NUP107	3232	3195.0
SNRPG	3179	3068.0
NUP188	2117	4593.0
GEMIN5	4699	2018.0
NUP160	3998	2314.0
DDX20	4951	1841.0
SMN1	4028	2156.5
SNRPD1	3996	1707.0
GEMIN7	2344	2502.0
NUP214	3124	1845.0
SNUPN	2836	1926.0
SEH1L	1085	4110.0

Click HERE to show all gene set members

All member genes

	human	mouse
AAAS	-3476	40.0
CLNS1A	155	1480.0
DDX20	4951	1841.0
GEMIN2	3264	-1925.0
GEMIN5	4699	2018.0
GEMIN6	3429	314.0
GEMIN7	2344	2502.0
GEMIN8	94	1167.0
NCBP1	-1736	4720.0
NCBP2	4188	-2519.0
NDC1	1273	-322.0
NUP107	3232	3195.0
NUP133	889	-2580.0
NUP153	4762	4031.0
NUP155	4306	2897.0
NUP160	3998	2314.0
NUP188	2117	4593.0
NUP205	4438	3917.0
NUP214	3124	1845.0
NUP35	4571	2515.0
NUP37	-327	-873.0
NUP43	4562	193.0
NUP54	4508	4751.0
NUP85	3181	227.0
NUP88	1244	1407.0
NUP93	-1503	5229.0
NUP98	4235	5486.0
PHAX	4729	-485.0
PRMT5	933	2092.0
RAE1	4471	3078.0
RANBP2	4470	-562.0
SEC13	730	938.0
SEH1L	1085	4110.0
SMN1	4028	2156.5
SNRPB	3761	-2577.0
SNRPD1	3996	1707.0
SNRPD2	2043	-2933.0
SNRPD3	2384	-3590.0
SNRPE	3421	-1387.0
SNRPF	3777	-2345.0
SNRPG	3179	3068.0
SNUPN	2836	1926.0
TGS1	4576	2855.0
TPR	2984	275.0
WDR77	-799	-1323.0

---

---

snRNP Assembly

snRNP Assembly

metric	value
setSize	45
pMANOVA	4.91e-10
p.adjustMANOVA	1.38e-08
s.dist	0.588
s.human	0.556
s.mouse	0.192
p.human	1.1e-10
p.mouse	0.0258

Top 20 genes

Gene	human	mouse
NUP98	4235	5486.0
NUP54	4508	4751.0
NUP153	4762	4031.0
NUP205	4438	3917.0
RAE1	4471	3078.0
TGS1	4576	2855.0
NUP155	4306	2897.0
NUP35	4571	2515.0
NUP107	3232	3195.0
SNRPG	3179	3068.0
NUP188	2117	4593.0
GEMIN5	4699	2018.0
NUP160	3998	2314.0
DDX20	4951	1841.0
SMN1	4028	2156.5
SNRPD1	3996	1707.0
GEMIN7	2344	2502.0
NUP214	3124	1845.0
SNUPN	2836	1926.0
SEH1L	1085	4110.0

Click HERE to show all gene set members

All member genes

	human	mouse
AAAS	-3476	40.0
CLNS1A	155	1480.0
DDX20	4951	1841.0
GEMIN2	3264	-1925.0
GEMIN5	4699	2018.0
GEMIN6	3429	314.0
GEMIN7	2344	2502.0
GEMIN8	94	1167.0
NCBP1	-1736	4720.0
NCBP2	4188	-2519.0
NDC1	1273	-322.0
NUP107	3232	3195.0
NUP133	889	-2580.0
NUP153	4762	4031.0
NUP155	4306	2897.0
NUP160	3998	2314.0
NUP188	2117	4593.0
NUP205	4438	3917.0
NUP214	3124	1845.0
NUP35	4571	2515.0
NUP37	-327	-873.0
NUP43	4562	193.0
NUP54	4508	4751.0
NUP85	3181	227.0
NUP88	1244	1407.0
NUP93	-1503	5229.0
NUP98	4235	5486.0
PHAX	4729	-485.0
PRMT5	933	2092.0
RAE1	4471	3078.0
RANBP2	4470	-562.0
SEC13	730	938.0
SEH1L	1085	4110.0
SMN1	4028	2156.5
SNRPB	3761	-2577.0
SNRPD1	3996	1707.0
SNRPD2	2043	-2933.0
SNRPD3	2384	-3590.0
SNRPE	3421	-1387.0
SNRPF	3777	-2345.0
SNRPG	3179	3068.0
SNUPN	2836	1926.0
TGS1	4576	2855.0
TPR	2984	275.0
WDR77	-799	-1323.0

---

---

Fatty acid metabolism

Fatty acid metabolism

metric	value
setSize	102
pMANOVA	7.3e-10
p.adjustMANOVA	2e-08
s.dist	0.401
s.human	-0.222
s.mouse	-0.333
p.human	0.000108
p.mouse	6.44e-09

Top 20 genes

Gene	human	mouse
CRAT	-5334	-4863.0
ACOT11	-5260	-4722.0
ACADVL	-4952	-4770.0
ABCD1	-5486	-3968.0
ACAD10	-4565	-4492.0
ACADS	-4663	-4266.0
ECI2	-4454	-4351.0
ECHS1	-3895	-4648.0
PHYH	-4170	-4330.0
ECI1	-3975	-4524.0
CYP2J2	-5037	-3267.0
GPX4	-3706	-4293.0
ACSF3	-4301	-3595.0
NUDT7	-3378	-4518.0
ACSL1	-3367	-4378.0
ACOT2	-2912	-4940.5
PPT2	-3952	-3594.0
HADHA	-3202	-4418.0
HADH	-2786	-5075.0
ACOT13	-2994	-4635.0

Click HERE to show all gene set members

All member genes

	human	mouse
ABCC1	1074	2063.0
ABCD1	-5486	-3968.0
ACAA2	-2330	-4889.0
ACAD10	-4565	-4492.0
ACAD11	421	-5042.0
ACADL	-1021	-4991.0
ACADM	-1714	-4943.0
ACADS	-4663	-4266.0
ACADVL	-4952	-4770.0
ACBD4	-2075	-2337.0
ACBD5	-1208	-1600.0
ACLY	-2628	4526.0
ACOT1	1587	-4940.5
ACOT11	-5260	-4722.0
ACOT13	-2994	-4635.0
ACOT2	-2912	-4940.5
ACOT7	-716	4137.0
ACOT8	-957	-2654.0
ACOT9	478	5113.0
ACOX1	3989	2503.0
ACOX3	-2027	-4032.0
ACSF2	-5148	1368.0
ACSF3	-4301	-3595.0
ACSL1	-3367	-4378.0
ACSL3	3465	4487.0
ACSL4	481	-189.0
ALDH3A2	-71	1336.0
AMACR	4160	-4700.0
CBR4	3854	-4600.0
CPT1A	-357	-839.0
CPT2	555	-5057.0
CRAT	-5334	-4863.0
CROT	3694	4862.0
CYP2J2	-5037	-3267.0
CYP2U1	-3305	-3638.0
DBI	-2859	-619.0
DECR1	-2617	-4927.0
DECR2	-2311	1855.0
ECHS1	-3895	-4648.0
ECI1	-3975	-4524.0
ECI2	-4454	-4351.0
EHHADH	-1005	-906.0
ELOVL1	-3641	5078.0
ELOVL5	4908	602.0
ELOVL6	1603	4205.0
EPHX2	-2227	-4973.0
FADS1	-4196	4323.0
FADS2	-4594	2686.0
FASN	-4976	4216.0
GGT5	-954	-2472.0
GPX1	-4411	-553.0
GPX4	-3706	-4293.0
HACL1	4520	-3057.0
HADH	-2786	-5075.0
HADHA	-3202	-4418.0
HADHB	-2035	-4747.0
HPGD	1681	-261.0
HSD17B12	2118	5293.0
HSD17B4	689	-4557.0
LTA4H	1584	2751.0
MAPKAPK2	-2489	-1825.0
MCAT	-628	-4342.0
MCEE	-816	-4855.0
MECR	-3190	-3135.0
MID1IP1	2058	-2839.0
MLYCD	-2169	-5081.0
MMAA	2798	-4294.0
MORC2	4923	-3070.0
NDUFAB1	1151	-3286.0
NUDT19	-2286	-2667.0
NUDT7	-3378	-4518.0
PCCA	-2597	-4409.0
PCCB	-165	-4900.0
PCTP	-322	-3225.0
PECR	-1213	-2572.0
PHYH	-4170	-4330.0
PLA2G4A	603	4806.0
PON2	-2005	183.0
PPARD	-4213	2330.0
PPT1	2553	-643.0
PPT2	-3952	-3594.0
PRKAA2	-3219	-2647.0
PRKAB2	-2332	-3109.0
PRKAG2	-3237	502.0
PTGES	-495	-2335.0
PTGES2	-2699	-3773.0
PTGES3	1328	2246.0
PTGIS	-1921	2930.0
PTGR1	3646	3810.0
PTGR2	-1055	-5011.0
PTGS1	-854	3113.0
RXRA	-5519	1619.0
SCD	-5600	4486.0
SCP2	-862	-4948.0
SLC22A5	-4653	-2437.0
SLC25A1	-2688	4605.0
SLC25A17	4134	3081.0
SLC25A20	-3511	-3661.0
SLC27A3	-132	589.0
TECR	-4006	-2570.0
THEM4	-3616	-2987.0
THRSP	-4308	441.0

---

---

RHO GTPase Effectors

RHO GTPase Effectors

metric	value
setSize	173
pMANOVA	7.6e-10
p.adjustMANOVA	2.04e-08
s.dist	0.295
s.human	0.0716
s.mouse	0.286
p.human	0.106
p.mouse	1.03e-10

Top 20 genes

Gene	human	mouse
DIAPH2	4914	5143
PKN2	4933	5115
NUP98	4235	5486
RHOB	4609	4443
ROCK1	4876	3865
NCKAP1	3563	5090
MAPRE1	3454	5215
PPP2R5A	4590	3889
ACTR2	3547	5008
PPP1R12A	4131	4053
DAAM1	3085	5018
NDEL1	4631	3278
ZWINT	2778	5457
DIAPH1	3282	4405
PDPK1	3443	3947
RCC2	4178	3180
ABI1	3792	3443
AHCTF1	4662	2760
CENPL	3768	3397
YWHAB	3680	3468

Click HERE to show all gene set members

All member genes

	human	mouse
ABI1	3792	3443
ABI2	-308	5438
ABL1	-4533	1377
ACTB	940	5427
ACTG1	-3075	5370
ACTR2	3547	5008
ACTR3	1376	5496
AHCTF1	4662	2760
AR	-4468	-4062
ARPC1A	-120	2226
ARPC1B	669	4872
ARPC2	1357	2489
ARPC3	2873	1716
ARPC4	1698	-1177
ARPC5	2295	5164
B9D2	1676	-3727
BAIAP2	-641	5424
BRK1	2026	-636
BUB3	4201	-1316
CALM1	-4464	1071
CDC42	3308	965
CDKN1B	-3284	-2637
CENPC	3555	-133
CENPL	3768	3397
CENPO	1005	3332
CENPQ	1344	5114
CENPT	-2196	4477
CFL1	-909	5151
CIT	-2025	2541
CKAP5	-3973	78
CLASP1	-3713	3198
CLASP2	2507	2478
CLIP1	418	-371
CTNNA1	-2198	2829
CTNNB1	1714	2956
CTTN	-4605	5097
CYBA	-633	2247
CYBB	-2550	3868
CYFIP2	-3775	-2981
DAAM1	3085	5018
DIAPH1	3282	4405
DIAPH2	4914	5143
DLG4	-1594	1830
DSN1	2075	-665
DVL1	-5428	-3679
DVL2	-2215	-3951
DVL3	-4897	2735
DYNC1H1	-1442	1264
DYNC1I2	2591	172
DYNC1LI1	2883	981
DYNC1LI2	1750	3473
DYNLL1	-1331	3935
EVL	-3566	-1001
FLNA	-3248	4449
FMNL1	-5159	-64
FMNL2	-650	4673
FMNL3	-1192	2401
GOPC	4735	-2584
GRB2	-4050	3027
H2AFX	2356	5181
INCENP	3676	1455
IQGAP1	-415	4295
ITGB1	956	5174
ITGB3BP	1048	-2794
KDM1A	249	5433
KDM4C	814	-807
KIF18A	3832	2448
KIF2A	-4390	4073
KIF5A	4430	584
KIF5B	838	4559
KLC1	-3922	2207
KLC2	-1732	-487
KLC4	-3559	-2759
KTN1	1427	1915
LIMK1	-4857	3467
LIMK2	-5357	-3001
MAD1L1	-3382	1367
MAD2L1	1101	1981
MAPK1	1988	-969
MAPK11	-3385	1370
MAPK14	-1562	-2824
MAPK3	-1024	4464
MAPRE1	3454	5215
MEN1	1348	426
MIS12	2400	5092
MYH10	50	5272
MYH14	-3853	-3524
MYH9	-1879	4997
MYL12B	1563	594
MYL6	-3628	1353
MYL9	-4777	-1049
MYLK	-3879	1507
NCK1	3718	2059
NCKAP1	3563	5090
NCKIPSD	-2821	3136
NCOA2	146	558
NDE1	4322	-1640
NDEL1	4631	3278
NF2	-1449	-3031
NUDC	3212	-860
NUP107	3232	3195
NUP133	889	-2580
NUP160	3998	2314
NUP37	-327	-873
NUP43	4562	193
NUP85	3181	227
NUP98	4235	5486
PAFAH1B1	-2026	1737
PAK1	-5419	-4706
PAK2	1525	5331
PDPK1	3443	3947
PFN1	467	-2704
PFN2	-4209	-2786
PIK3C3	3439	-1596
PIK3R4	3839	-3124
PIN1	-3515	-3234
PKN1	-4379	2357
PKN2	4933	5115
PKN3	-3848	310
PPP1CB	-1374	-3335
PPP1CC	4081	-1627
PPP1R12A	4131	4053
PPP1R12B	-5005	2701
PPP2CA	4482	1672
PPP2CB	2458	2352
PPP2R1A	-4013	-681
PPP2R1B	3028	3194
PPP2R5A	4590	3889
PPP2R5B	-1524	-765
PPP2R5C	-2508	-293
PPP2R5D	-3449	-620
PPP2R5E	4644	2107
PRC1	112	4093
PRKCA	-2938	1125
PRKCD	-4276	1141
PTK2	-2497	2145
RAC1	2525	-240
RAC2	41	4138
RANBP2	4470	-562
RANGAP1	483	4468
RCC2	4178	3180
RHOA	539	4106
RHOB	4609	4443
RHOC	-4944	4844
RHOG	-1207	5167
RHOQ	-1357	-1546
RHPN2	3217	517
ROCK1	4876	3865
ROCK2	2205	1929
RTKN	-5092	-1124
SCAI	-726	-536
SEC13	730	938
SEH1L	1085	4110
SKA2	2399	946
SRC	-3910	3763
SRF	-4281	3531
TAOK1	1644	130
TAX1BP3	-710	3864
WASF2	-4656	3026
WASF3	-1015	1293
WASL	2683	4511
WIPF1	-2552	2457
WIPF2	3299	-608
WIPF3	-5107	-4936
XPO1	990	2133
YWHAB	3680	3468
YWHAE	1394	-2051
YWHAG	-2372	1012
YWHAH	-2777	3808
YWHAQ	963	3949
YWHAZ	2019	4919
ZW10	1474	3364
ZWINT	2778	5457

---

---

HIV Infection

HIV Infection

metric	value
setSize	187
pMANOVA	8.19e-10
p.adjustMANOVA	2.15e-08
s.dist	0.297
s.human	0.243
s.mouse	0.17
p.human	1.09e-08
p.mouse	6.69e-05

Top 20 genes

Gene	human	mouse
TAF4B	4967	5489
TAF7	4717	5281
GTF2B	4276	5493
NUP98	4235	5486
GTF2F1	4999	4439
NUP54	4508	4751
POLR2A	3861	5366
GTF2F2	4067	5047
GTF2A1	4730	4204
AP1G1	4140	4718
NUP153	4762	4031
RNMT	4864	3622
TAF3	4294	4087
NUP205	4438	3917
VPS4B	4523	3841
KPNB1	3619	4744
SUPT16H	3885	4417
TAF2	4591	3536
SLC25A5	3467	4224
RAE1	4471	3078

Click HERE to show all gene set members

All member genes

	human	mouse
AAAS	-3476	40.0
AP1B1	-4552	1126.0
AP1G1	4140	4718.0
AP1M1	3732	1165.0
AP1S1	-1410	80.0
AP1S2	-1634	3070.0
AP2A1	-3632	-3002.0
AP2A2	-1058	5459.0
AP2B1	-1157	4733.0
AP2M1	-2746	1678.0
AP2S1	1777	-582.0
ARF1	566	3011.0
ATP6V1H	-57	1416.0
B2M	-731	-1801.0
BANF1	-2281	-1690.0
BTRC	-1187	-2761.0
CCNH	3825	-1939.0
CCNK	3139	-346.0
CCNT1	4896	309.0
CCNT2	4381	-4634.0
CD28	-2910	-4611.0
CDK7	1571	326.0
CDK9	-1348	4755.0
CHMP2A	1155	2070.0
CHMP2B	967	-4699.0
CHMP3	-3919	1246.0
CHMP4B	-1125	-1336.0
CHMP5	3372	-1350.0
CHMP6	-4368	-1833.0
CHMP7	1743	-1108.0
CTDP1	2071	4946.0
CUL5	2599	-2062.0
ELL	-3990	3539.0
ELMO1	-2166	2524.0
ERCC2	824	4319.0
ERCC3	473	3200.0
FEN1	4094	-1467.0
FURIN	-4221	4897.0
FYN	-2850	4537.0
GTF2A1	4730	4204.0
GTF2A2	4648	-2956.0
GTF2B	4276	5493.0
GTF2E1	2188	896.0
GTF2E2	2041	-136.0
GTF2F1	4999	4439.0
GTF2F2	4067	5047.0
GTF2H1	3886	647.0
GTF2H2	4419	-2426.5
GTF2H3	-1925	-664.0
GTF2H5	-878	-3245.0
HMGA1	598	5468.0
KPNA1	1833	4786.0
KPNB1	3619	4744.0
LIG1	-3127	898.0
LIG4	2394	-1960.0
MNAT1	830	-3106.0
MVB12A	-2807	-2371.0
MVB12B	-5576	-1428.0
NCBP1	-1736	4720.0
NCBP2	4188	-2519.0
NDC1	1273	-322.0
NEDD4L	4279	95.0
NELFA	356	3429.0
NELFB	-1196	2017.0
NELFCD	1896	-2826.0
NELFE	-2178	3913.0
NMT1	-1463	4510.0
NMT2	2059	4895.0
NUP107	3232	3195.0
NUP133	889	-2580.0
NUP153	4762	4031.0
NUP155	4306	2897.0
NUP160	3998	2314.0
NUP188	2117	4593.0
NUP205	4438	3917.0
NUP214	3124	1845.0
NUP35	4571	2515.0
NUP37	-327	-873.0
NUP43	4562	193.0
NUP54	4508	4751.0
NUP85	3181	227.0
NUP88	1244	1407.0
NUP93	-1503	5229.0
NUP98	4235	5486.0
PACS1	-4826	173.0
PAK2	1525	5331.0
PDCD6IP	1350	5265.0
POLR2A	3861	5366.0
POLR2B	4509	-3401.0
POLR2C	4529	-4002.0
POLR2D	1669	3230.0
POLR2E	-667	148.0
POLR2G	89	4349.0
POLR2H	-3927	2213.0
POLR2I	-154	-2504.0
POLR2K	2480	-3599.0
POLR2L	-4314	-1126.0
PPIA	-4031	4207.0
PSIP1	3390	1448.0
PSMA1	2820	4043.0
PSMA3	3434	-1035.0
PSMA4	769	-1962.0
PSMA6	2199	-1657.0
PSMA7	-2980	-1038.0
PSMB1	954	-1037.0
PSMB10	-1800	-831.0
PSMB2	618	-67.0
PSMB4	-235	-559.0
PSMB5	-4113	-2597.0
PSMB6	-793	-1795.0
PSMB7	-831	-2699.0
PSMB8	-675	-2510.0
PSMB9	-1611	-3558.0
PSMC1	449	1146.0
PSMC2	-1311	3386.0
PSMC3	-2439	-1846.0
PSMC4	2724	-205.0
PSMC5	1212	-1680.0
PSMC6	-2520	3114.0
PSMD1	2619	3210.0
PSMD10	-1227	361.0
PSMD11	995	5504.0
PSMD12	3831	-462.0
PSMD13	821	532.0
PSMD14	-635	3746.0
PSMD2	-713	741.0
PSMD3	-3343	-354.0
PSMD4	-214	968.0
PSMD5	1807	4479.0
PSMD6	3537	-3784.0
PSMD7	-2329	410.0
PSMD8	-3171	4292.0
PSMD9	4204	-3586.0
PSME1	-2771	-2861.0
PSME2	-4085	-41.0
PSME3	3333	491.0
PSME4	1960	2319.0
PSMF1	683	-1768.0
RAC1	2525	-240.0
RAE1	4471	3078.0
RAN	2329	575.0
RANBP1	745	3863.0
RANBP2	4470	-562.0
RANGAP1	483	4468.0
RBX1	-733	-2400.0
RCC1	997	4917.0
RNGTT	4414	-1456.0
RNMT	4864	3622.0
RPS27A	783	-2165.0
SEC13	730	938.0
SEH1L	1085	4110.0
SKP1	2028	-1286.0
SLC25A4	-1327	-4427.0
SLC25A5	3467	4224.0
SSRP1	1755	1765.0
SUPT16H	3885	4417.0
SUPT4H1	3648	-1692.0
SUPT5H	1321	4377.0
TAF1	1708	4363.0
TAF10	-273	547.0
TAF11	2962	-1678.0
TAF12	3100	3716.0
TAF13	4749	1646.0
TAF2	4591	3536.0
TAF3	4294	4087.0
TAF4	-1340	4027.0
TAF4B	4967	5489.0
TAF5	4309	1473.0
TAF6	-912	-885.0
TAF7	4717	5281.0
TAF9B	1874	-618.0
TBP	1137	3931.0
TCEA1	4037	163.0
TPR	2984	275.0
TSG101	260	1656.0
UBAP1	-1913	5312.0
UBC	2672	3877.0
VPS37A	1868	1922.0
VPS37B	-3496	3692.0
VPS37C	1403	3199.0
VPS4A	-1545	-2729.0
VPS4B	4523	3841.0
VTA1	3283	591.0
XPO1	990	2133.0
XRCC4	-4731	333.0
XRCC5	4010	1456.0
XRCC6	3225	-2097.0

---

---

GPCR downstream signalling

GPCR downstream signalling

metric	value
setSize	245
pMANOVA	8.93e-10
p.adjustMANOVA	2.29e-08
s.dist	0.224
s.human	-0.207
s.mouse	0.0834
p.human	2.64e-08
p.mouse	0.0255

Top 20 genes

Gene	human	mouse
RHOC	-4944	4844
P2RY6	-4646	5147
ARHGEF2	-4945	4225
LDLR	-3949	5260
TIAM2	-3379	5429
ABR	-5353	3387
RGS3	-5494	3152
CYSLTR1	-4110	4012
CXCL12	-4998	3271
CAMKK1	-3959	4041
SRC	-3910	3763
VAV2	-4959	2847
SDC3	-4619	2991
OPN3	-2839	4784
GNA12	-3059	4306
ARHGEF40	-5458	2410
NET1	-5146	2540
FGD1	-3972	3284
SDC4	-2393	5425
GRB2	-4050	3027

Click HERE to show all gene set members

All member genes

	human	mouse
ABHD12	-778	-482.0
ABHD6	-2808	-530.0
ABR	-5353	3387.0
ADCY1	-3780	-756.0
ADCY2	-4820	-4790.0
ADCY3	338	612.0
ADCY5	1967	3217.0
ADCY6	-4515	-3045.0
ADCY7	-2820	3300.0
ADCY9	-4889	-2586.0
ADM	-1822	-3530.0
ADRA2A	-4661	-686.0
ADRB2	-1092	-929.0
AGRN	-4903	783.0
AGT	-4723	-2282.0
AGTR1	1167	-2662.0
AHCYL1	-3386	2570.0
AKAP13	1322	667.0
AKR1B10	2786	-1511.5
AKT1	-4954	1242.0
AKT2	-4057	-3488.0
AKT3	1343	2419.0
ANXA1	537	4783.0
APOE	-1428	-1396.0
APP	-2792	154.0
ARHGEF1	1054	-217.0
ARHGEF10L	-5596	682.0
ARHGEF11	-1199	2030.0
ARHGEF12	2630	5108.0
ARHGEF17	-5387	85.0
ARHGEF18	2304	-1935.0
ARHGEF2	-4945	4225.0
ARHGEF25	-2669	-1024.0
ARHGEF26	4815	3641.0
ARHGEF3	-4589	-823.0
ARHGEF37	-5129	127.0
ARHGEF4	-3700	211.0
ARHGEF40	-5458	2410.0
ARHGEF6	2856	4594.0
ARHGEF7	-3605	3212.0
ARHGEF9	-3989	-4009.0
ARRB1	-3133	2633.0
ARRB2	-1089	3740.0
C3	4311	-2705.0
CALCRL	2945	-2409.0
CALM1	-4464	1071.0
CAMK2A	-5527	-3819.0
CAMK2B	-5497	-2856.0
CAMK2D	-2223	5094.0
CAMK2G	-2097	-4184.0
CAMKK1	-3959	4041.0
CAMKK2	-4965	2096.0
CDC42	3308	965.0
CDK5	-1007	-2874.0
CREB1	2179	-1920.0
CX3CR1	307	4879.0
CXCL12	-4998	3271.0
CXCL16	-920	-543.0
CYP4V2	-2707	73.0
CYSLTR1	-4110	4012.0
DAGLA	-5158	-1202.0
DAGLB	3782	-3217.0
DGKA	-2368	-2473.0
DGKB	-4489	-1599.0
DGKD	-5077	2121.0
DGKE	1911	-4489.0
DGKH	3337	3991.0
DGKQ	-2188	-3043.0
DGKZ	-5581	-3517.0
DHRS3	-611	377.0
EDNRA	1038	2094.0
EDNRB	1473	-1220.0
EGFR	424	2978.0
F2R	1667	2871.0
F2RL1	3379	5479.0
FGD1	-3972	3284.0
FGD3	-3665	3129.0
FGD4	-4717	-3651.0
FNTA	1578	-3409.0
FNTB	-690	3507.0
GABBR1	-2887	-778.0
GNA11	-1689	2150.0
GNA12	-3059	4306.0
GNA13	-209	5323.0
GNAI1	183	1373.0
GNAI2	800	2142.0
GNAI3	4221	4647.0
GNAL	-3374	3533.0
GNAQ	4906	4533.0
GNAS	-3163	-1742.0
GNB1	177	5374.0
GNB2	-3870	1232.0
GNB3	-3272	-676.0
GNB4	-3491	1634.0
GNB5	879	-2818.0
GNG11	4695	-4457.0
GNG12	612	604.0
GNG2	802	-2139.0
GNG5	415	-3220.0
GNG7	-2742	-4220.0
GPC1	-5269	-1574.0
GPC4	-5170	-4334.0
GPC6	-2385	1959.0
GPSM1	-3915	1306.0
GPSM2	-3093	3500.0
GRB2	-4050	3027.0
GRK4	-1206	945.0
GRK5	-1067	-563.0
GRK6	-1110	2111.0
HBEGF	3484	5518.0
HEBP1	18	-537.0
HRAS	-4545	-4872.0
HSPG2	-5351	1532.0
HTR7	2315	-3527.0
ITPR1	4903	1106.0
ITPR2	1242	53.0
ITPR3	-3631	-2403.0
ITSN1	524	-2768.0
KALRN	-5340	-990.0
KPNA2	5007	4653.0
KRAS	3546	5146.0
LDLR	-3949	5260.0
LPAR1	-2162	3140.0
LPAR4	-1042	-1474.0
LPAR6	2280	1088.0
LRP1	-3652	3049.0
LRP10	-3203	1445.0
LRP12	4543	5259.0
MAPK1	1988	-969.0
MAPK3	-1024	4464.0
MAPK7	-729	2102.0
MCF2L	-5254	1060.0
METAP1	2806	-592.0
METAP2	0	1920.0
MGLL	-5374	-5059.0
MYO7A	-4056	2325.0
NAPEPLD	-3083	3144.0
NBEA	-4442	-507.0
NET1	-5146	2540.0
NMB	-1654	-2613.0
NMT1	-1463	4510.0
NMT2	2059	4895.0
NRAS	4354	1003.0
OBSCN	-5563	-275.0
OPN3	-2839	4784.0
P2RY2	-5283	-3360.0
P2RY6	-4646	5147.0
PAK1	-5419	-4706.0
PDE10A	2072	2109.0
PDE1A	2411	-405.0
PDE3A	315	468.0
PDE4A	-3306	-5113.0
PDE4B	3915	-2949.0
PDE4C	-2010	-3176.0
PDE4D	-1433	-3425.0
PDE7A	-2549	-3215.0
PDE7B	-2696	-5066.0
PDE8A	-324	3438.0
PDPK1	3443	3947.0
PENK	634	-3005.0
PIK3CA	365	4218.0
PIK3R1	2896	-813.0
PIK3R3	3188	3545.0
PLA2G4A	603	4806.0
PLB1	-3857	-1943.0
PLCB1	-1580	-2084.0
PLCB3	-3863	993.0
PLCB4	-4274	-2681.0
PLEKHG2	-708	4175.0
PLEKHG5	-4706	-2803.0
PLXNB1	-5451	-185.0
PPP1CA	-4408	-15.0
PPP2CA	4482	1672.0
PPP2CB	2458	2352.0
PPP2R1A	-4013	-681.0
PPP2R1B	3028	3194.0
PPP2R5D	-3449	-620.0
PPP3CA	109	-1172.0
PPP3CB	-3435	-1839.0
PPP3CC	-3311	-2196.0
PREX1	188	2037.0
PRKACA	-4691	-4303.0
PRKACB	-2659	-360.0
PRKAR1A	-3106	203.0
PRKAR1B	-2442	3659.0
PRKAR2A	-2664	1823.0
PRKAR2B	3460	1006.0
PRKCA	-2938	1125.0
PRKCD	-4276	1141.0
PRKCE	-4307	-348.0
PRKCQ	-5095	-4724.0
PRKX	-1471	5241.0
PSAP	-2247	-4177.0
PTGER4	4219	2196.0
PTGIR	-370	3747.0
PTH1R	-2770	-90.0
PTHLH	-3836	-66.0
RAMP1	-5448	-646.0
RASGRF2	4373	-3126.0
RASGRP2	-2556	-4004.0
RBP1	2113	2547.0
RDH10	1095	4775.0
RDH11	2085	5274.0
RDH5	-3933	1560.0
REEP1	-5059	-2153.0
REEP2	-2968	-463.0
REEP3	2053	4553.0
REEP4	1148	4143.0
REEP5	-3723	-3834.0
REEP6	-1143	-450.0
RETSAT	2667	-4958.0
RGS10	-785	2024.0
RGS12	-4393	2043.0
RGS14	-5528	-1896.0
RGS16	-723	5075.0
RGS19	-2099	3025.0
RGS2	-581	4051.0
RGS3	-5494	3152.0
RGS4	1724	4741.0
RGS5	2155	-3665.0
RGS9BP	-2609	4386.0
RHOA	539	4106.0
RHOB	4609	4443.0
RHOC	-4944	4844.0
ROCK1	4876	3865.0
ROCK2	2205	1929.0
RPS6KA1	-1481	-1813.0
RPS6KA2	-4748	-4135.0
RPS6KA3	952	2296.0
S1PR2	520	3630.0
S1PR3	2047	-31.0
SDC1	-2046	1023.0
SDC2	1756	4994.0
SDC3	-4619	2991.0
SDC4	-2393	5425.0
SOS1	-1962	2326.0
SOS2	-563	-2646.0
SRC	-3910	3763.0
TAS1R1	-4010	-2497.0
TIAM1	2024	-347.0
TIAM2	-3379	5429.0
TRIO	1163	-378.0
UTS2R	-5043	1755.0
VAV2	-4959	2847.0
VAV3	187	-276.0

---

---

Citric acid cycle (TCA cycle)

Citric acid cycle (TCA cycle)

metric	value
setSize	21
pMANOVA	1.45e-09
p.adjustMANOVA	3.64e-08
s.dist	0.833
s.human	-0.243
s.mouse	-0.797
p.human	0.0539
p.mouse	2.5e-10

Top 20 genes

Gene	human	mouse
IDH2	-5216	-4835
SDHA	-4773	-4748
OGDH	-5268	-4106
MDH2	-4361	-4332
ACO2	-3822	-4534
SDHC	-3712	-4323
IDH3G	-4178	-3714
NNT	-3325	-4200
IDH3B	-2881	-4194
IDH3A	-2155	-4265
FAHD1	-1771	-4836
SUCLG2	-1167	-4765
DLST	-323	-4762
SUCLG1	-31	-4434

Click HERE to show all gene set members

All member genes

	human	mouse
ACO2	-3822	-4534
CS	3653	-4328
DLD	1187	-4834
DLST	-323	-4762
FAHD1	-1771	-4836
FH	287	-4146
IDH2	-5216	-4835
IDH3A	-2155	-4265
IDH3B	-2881	-4194
IDH3G	-4178	-3714
MDH2	-4361	-4332
ME2	-1789	3649
ME3	4207	-3631
NNT	-3325	-4200
OGDH	-5268	-4106
SDHA	-4773	-4748
SDHB	431	-4408
SDHC	-3712	-4323
SUCLA2	1517	-4804
SUCLG1	-31	-4434
SUCLG2	-1167	-4765

---

---

Infectious disease

Infectious disease

metric	value
setSize	533
pMANOVA	2.47e-09
p.adjustMANOVA	6.08e-08
s.dist	0.173
s.human	0.0913
s.mouse	0.147
p.human	0.000374
p.mouse	9.46e-09

Top 20 genes

Gene	human	mouse
TAF4B	4967	5489.0
HSPA1A	4887	5534.5
TAF7	4717	5281.0
GTF2B	4276	5493.0
KPNA2	5007	4653.0
NUP98	4235	5486.0
PLK2	4764	4721.0
SFPQ	4544	4884.0
GTF2F1	4999	4439.0
BRD4	4547	4878.0
NUP54	4508	4751.0
POLR2A	3861	5366.0
STAM	3932	5249.0
GTF2F2	4067	5047.0
HSP90AA1	3656	5525.0
EZH2	4698	4282.0
TRIM28	4209	4779.0
GTF2A1	4730	4204.0
GNAI3	4221	4647.0
AP1G1	4140	4718.0

Click HERE to show all gene set members

All member genes

	human	mouse
AAAS	-3476	40.0
ABI1	3792	3443.0
ABI2	-308	5438.0
ABL1	-4533	1377.0
ACTB	940	5427.0
ACTG1	-3075	5370.0
ACTR2	3547	5008.0
ACTR3	1376	5496.0
ADAM17	2407	736.0
ADCY1	-3780	-756.0
ADCY2	-4820	-4790.0
ADCY3	338	612.0
ADCY5	1967	3217.0
ADCY6	-4515	-3045.0
ADCY7	-2820	3300.0
ADCY9	-4889	-2586.0
ADM	-1822	-3530.0
ADRB2	-1092	-929.0
AHCYL1	-3386	2570.0
ANTXR1	-1237	1638.0
ANTXR2	-1075	2695.0
AP1B1	-4552	1126.0
AP1G1	4140	4718.0
AP1M1	3732	1165.0
AP1S1	-1410	80.0
AP1S2	-1634	3070.0
AP2A1	-3632	-3002.0
AP2A2	-1058	5459.0
AP2B1	-1157	4733.0
AP2M1	-2746	1678.0
AP2S1	1777	-582.0
ARF1	566	3011.0
ARID4A	4673	-1354.0
ARID4B	4763	142.0
ARPC1A	-120	2226.0
ARPC1B	669	4872.0
ARPC2	1357	2489.0
ARPC3	2873	1716.0
ARPC4	1698	-1177.0
ARPC5	2295	5164.0
ATP1A1	-4096	5364.0
ATP1A2	-5569	-4880.0
ATP1A3	206	3197.0
ATP1B1	2576	-3831.0
ATP1B3	-598	2812.0
ATP6V1H	-57	1416.0
B2M	-731	-1801.0
BAIAP2	-641	5424.0
BANF1	-2281	-1690.0
BECN1	3274	-2133.0
BRD4	4547	4878.0
BRK1	2026	-636.0
BRMS1	-28	3065.0
BTRC	-1187	-2761.0
C3	4311	-2705.0
CALCRL	2945	-2409.0
CALM1	-4464	1071.0
CALR	1534	4814.0
CANX	-836	4822.0
CASP1	-1298	1115.0
CBL	1736	1563.0
CBLL1	4088	2339.0
CBX1	3736	603.0
CCNH	3825	-1939.0
CCNK	3139	-346.0
CCNT1	4896	309.0
CCNT2	4381	-4634.0
CD28	-2910	-4611.0
CD9	2203	3954.0
CDC42	3308	965.0
CDK7	1571	326.0
CDK9	-1348	4755.0
CHD3	-3721	-2281.0
CHD4	-4283	1724.0
CHMP1A	2879	-51.0
CHMP2A	1155	2070.0
CHMP2B	967	-4699.0
CHMP3	-3919	1246.0
CHMP4B	-1125	-1336.0
CHMP5	3372	-1350.0
CHMP6	-4368	-1833.0
CHMP7	1743	-1108.0
CLTA	1218	-119.0
CLTC	2268	2273.0
COMT	-5098	-4814.0
CPSF4	862	4202.0
CRBN	-992	788.0
CREB1	2179	-1920.0
CRK	2145	4206.0
CTDP1	2071	4946.0
CTNNB1	1714	2956.0
CTNND1	949	4243.0
CUL5	2599	-2062.0
CYBA	-633	2247.0
CYFIP2	-3775	-2981.0
CYSLTR1	-4110	4012.0
DAD1	498	-1032.0
DAXX	4449	3854.0
DBP	-538	-2669.0
DDOST	320	4978.0
DDX5	4191	-363.0
DNAJC3	1950	4619.0
DOCK1	-226	2409.0
DUSP16	3082	3867.0
DUT	-592	-2679.0
DVL1	-5428	-3679.0
DVL2	-2215	-3951.0
DVL3	-4897	2735.0
DYNC1H1	-1442	1264.0
DYNC1I2	2591	172.0
DYNC1LI1	2883	981.0
DYNC1LI2	1750	3473.0
DYNLL1	-1331	3935.0
EDEM2	1319	4006.0
EED	3304	3108.0
EEF2	-2853	740.0
EGFR	424	2978.0
EIF2AK2	-486	-129.0
ELK1	-3862	1269.0
ELL	-3990	3539.0
ELMO1	-2166	2524.0
ELMO2	-354	1439.0
ENO1	-4083	2108.0
ENTPD5	-4035	-459.0
EPS15	5	-415.0
ERCC2	824	4319.0
ERCC3	473	3200.0
EZH2	4698	4282.0
FAU	2272	2649.0
FEN1	4094	-1467.0
FKBP4	1305	-2525.0
FURIN	-4221	4897.0
FUT8	3313	-1125.0
FXYD1	-2722	-4881.0
FYN	-2850	4537.0
FZD7	1006	-1637.0
GALNT1	1478	1052.0
GANAB	489	2794.0
GATAD2A	-975	5411.0
GATAD2B	304	4882.0
GGT5	-954	-2472.0
GNAI1	183	1373.0
GNAI2	800	2142.0
GNAI3	4221	4647.0
GNAS	-3163	-1742.0
GNB1	177	5374.0
GNB2	-3870	1232.0
GNB3	-3272	-676.0
GNB4	-3491	1634.0
GNB5	879	-2818.0
GNG11	4695	-4457.0
GNG12	612	604.0
GNG2	802	-2139.0
GNG5	415	-3220.0
GNG7	-2742	-4220.0
GPS2	2002	-25.0
GRB2	-4050	3027.0
GRSF1	-3131	-4622.0
GSK3A	3319	-2089.0
GSK3B	897	4692.0
GTF2A1	4730	4204.0
GTF2A2	4648	-2956.0
GTF2B	4276	5493.0
GTF2E1	2188	896.0
GTF2E2	2041	-136.0
GTF2F1	4999	4439.0
GTF2F2	4067	5047.0
GTF2H1	3886	647.0
GTF2H2	4419	-2426.5
GTF2H3	-1925	-664.0
GTF2H5	-878	-3245.0
HBEGF	3484	5518.0
HDAC2	4386	-579.0
HDAC3	-178	-2363.0
HGS	2410	5267.0
HMG20B	704	-3309.0
HMGA1	598	5468.0
HNRNPK	3054	2807.0
HSP90AA1	3656	5525.0
HSP90AB1	-639	5203.0
HSPA1A	4887	5534.5
HTR7	2315	-3527.0
IFNAR1	3645	1778.0
IFNAR2	-1316	1704.0
IFNGR1	2506	1520.0
IFNGR2	-386	-3292.0
IL1R1	-3018	4729.0
IL6R	-5515	2529.0
IMPDH1	-827	3626.0
IMPDH2	822	-801.0
IPO5	1982	4378.0
IRS1	-5550	-3910.0
ISG15	-3928	-331.0
ITGA4	-2878	-2673.0
ITGB1	956	5174.0
ITPR1	4903	1106.0
ITPR2	1242	53.0
ITPR3	-3631	-2403.0
JAK1	-1869	4962.0
JAK2	-2569	-2171.0
JUN	2469	5472.0
KDM1A	249	5433.0
KPNA1	1833	4786.0
KPNA2	5007	4653.0
KPNA3	-2337	-979.0
KPNA4	1501	5379.0
KPNB1	3619	4744.0
LIG1	-3127	898.0
LIG4	2394	-1960.0
LYN	785	2842.0
MAGT1	1192	-616.0
MAN1B1	-2087	1802.0
MAN2A1	4002	2434.0
MAP1LC3B	2569	-3160.0
MAP2K1	-506	-3734.0
MAP2K2	-3813	-2235.0
MAP2K3	-4716	3926.0
MAP2K4	8	1873.0
MAP2K6	1456	-4331.0
MAP2K7	794	-4191.0
MAPK1	1988	-969.0
MAPK14	-1562	-2824.0
MAPK3	-1024	4464.0
MAPK8	457	1743.0
MBD3	-3419	804.0
MET	-3529	4440.0
MGAT1	-1603	-1851.0
MGAT2	1418	5367.0
MGAT4A	268	4101.0
MGAT4B	-4707	1392.0
MGAT5	3014	918.0
MNAT1	830	-3106.0
MOGS	-3129	4078.0
MTA1	-4102	3149.0
MTA2	3682	-1298.0
MTA3	-2123	-1721.0
MVB12A	-2807	-2371.0
MVB12B	-5576	-1428.0
MYH2	-3080	-1826.0
MYH9	-1879	4997.0
MYO10	1381	2797.0
MYO1C	-4842	4663.0
MYO5A	-885	4252.0
MYO9B	-1901	4621.0
NCBP1	-1736	4720.0
NCBP2	4188	-2519.0
NCK1	3718	2059.0
NCKAP1	3563	5090.0
NCKIPSD	-2821	3136.0
NCOR1	2625	-1011.0
NCOR2	-5167	-143.0
NDC1	1273	-322.0
NEDD4L	4279	95.0
NELFA	356	3429.0
NELFB	-1196	2017.0
NELFCD	1896	-2826.0
NELFE	-2178	3913.0
NFKB1	-4233	2228.0
NFKB2	-3926	2289.0
NMT1	-1463	4510.0
NMT2	2059	4895.0
NR3C1	985	425.0
NT5E	1998	1133.0
NUP107	3232	3195.0
NUP133	889	-2580.0
NUP153	4762	4031.0
NUP155	4306	2897.0
NUP160	3998	2314.0
NUP188	2117	4593.0
NUP205	4438	3917.0
NUP214	3124	1845.0
NUP35	4571	2515.0
NUP37	-327	-873.0
NUP43	4562	193.0
NUP54	4508	4751.0
NUP85	3181	227.0
NUP88	1244	1407.0
NUP93	-1503	5229.0
NUP98	4235	5486.0
P2RX4	-1108	2922.0
PACS1	-4826	173.0
PAK2	1525	5331.0
PARP1	-2423	278.0
PARP10	-4978	-2487.0
PARP14	-1721	-1772.0
PARP16	-79	-3339.0
PARP4	-4440	1808.0
PARP6	448	-97.0
PARP8	4194	1235.0
PARP9	-3114	-1883.0
PDCD6IP	1350	5265.0
PGK1	-1414	-3278.0
PHF21A	-4739	-533.0
PIK3C3	3439	-1596.0
PIK3R4	3839	-3124.0
PLCG1	-3955	-1787.0
PLK2	4764	4721.0
PML	3338	3242.0
POLR2A	3861	5366.0
POLR2B	4509	-3401.0
POLR2C	4529	-4002.0
POLR2D	1669	3230.0
POLR2E	-667	148.0
POLR2G	89	4349.0
POLR2H	-3927	2213.0
POLR2I	-154	-2504.0
POLR2K	2480	-3599.0
POLR2L	-4314	-1126.0
PPIA	-4031	4207.0
PRKACA	-4691	-4303.0
PRKACB	-2659	-360.0
PRKAR1A	-3106	203.0
PRKAR1B	-2442	3659.0
PRKAR2A	-2664	1823.0
PRKAR2B	3460	1006.0
PRKCSH	-268	367.0
PRKX	-1471	5241.0
PSIP1	3390	1448.0
PSMA1	2820	4043.0
PSMA3	3434	-1035.0
PSMA4	769	-1962.0
PSMA6	2199	-1657.0
PSMA7	-2980	-1038.0
PSMB1	954	-1037.0
PSMB10	-1800	-831.0
PSMB2	618	-67.0
PSMB4	-235	-559.0
PSMB5	-4113	-2597.0
PSMB6	-793	-1795.0
PSMB7	-831	-2699.0
PSMB8	-675	-2510.0
PSMB9	-1611	-3558.0
PSMC1	449	1146.0
PSMC2	-1311	3386.0
PSMC3	-2439	-1846.0
PSMC4	2724	-205.0
PSMC5	1212	-1680.0
PSMC6	-2520	3114.0
PSMD1	2619	3210.0
PSMD10	-1227	361.0
PSMD11	995	5504.0
PSMD12	3831	-462.0
PSMD13	821	532.0
PSMD14	-635	3746.0
PSMD2	-713	741.0
PSMD3	-3343	-354.0
PSMD4	-214	968.0
PSMD5	1807	4479.0
PSMD6	3537	-3784.0
PSMD7	-2329	410.0
PSMD8	-3171	4292.0
PSMD9	4204	-3586.0
PSME1	-2771	-2861.0
PSME2	-4085	-41.0
PSME3	3333	491.0
PSME4	1960	2319.0
PSMF1	683	-1768.0
PTGER4	4219	2196.0
PTGES3	1328	2246.0
PTGIR	-370	3747.0
PTH1R	-2770	-90.0
PTHLH	-3836	-66.0
PTK2	-2497	2145.0
PYCARD	-2810	3218.0
RAB5A	2109	4613.0
RAB7A	-383	3232.0
RAC1	2525	-240.0
RAE1	4471	3078.0
RAMP1	-5448	-646.0
RAN	2329	575.0
RANBP1	745	3863.0
RANBP2	4470	-562.0
RANGAP1	483	4468.0
RB1	-2449	831.0
RBBP4	1072	728.0
RBBP7	-924	-1007.0
RBX1	-733	-2400.0
RCC1	997	4917.0
RCOR1	4776	3876.0
RELA	1783	4454.0
REST	1113	2845.0
RHBDF2	-2750	-107.0
RIPK1	325	189.0
RNF213	-4087	497.0
RNGTT	4414	-1456.0
RNMT	4864	3622.0
ROCK1	4876	3865.0
ROCK2	2205	1929.0
RPL10	-3902	3923.0
RPL11	-2249	-1971.0
RPL14	433	-875.0
RPL18	-1782	448.0
RPL18A	-2969	-320.0
RPL19	-502	-1379.0
RPL22	1231	-3446.0
RPL22L1	3380	2374.0
RPL23	-115	-2882.0
RPL26	1047	696.0
RPL28	-391	-1891.0
RPL3	-786	5412.0
RPL30	286	-3056.0
RPL31	-595	2894.0
RPL32	-367	-950.0
RPL34	1447	-1314.0
RPL35A	812	-1471.0
RPL36A	1261	-1408.0
RPL37	-715	-1311.0
RPL37A	-1043	554.0
RPL38	231	-953.0
RPL3L	-5212	-4614.0
RPL4	-522	-571.0
RPL5	1206	3360.0
RPL7	1440	-1894.0
RPL8	-2775	-928.0
RPLP2	-2469	-3389.0
RPN1	768	-2883.0
RPN2	497	2665.0
RPS11	-1582	-458.0
RPS12	-318	1501.0
RPS13	1131	-1994.0
RPS14	-1412	122.0
RPS15	-1799	-1082.0
RPS15A	-704	-237.0
RPS16	-1828	2010.0
RPS18	-974	-1404.0
RPS19	-2045	-882.0
RPS20	-1844	1712.0
RPS21	-1536	-2810.0
RPS23	-68	-749.0
RPS24	256	-1505.0
RPS26	-282	-1421.0
RPS27A	783	-2165.0
RPS27L	-616	-69.0
RPS29	-1140	-1275.0
RPS3	-544	116.0
RPS4X	83	97.0
RPS5	-1577	935.0
RPS6	-245	1237.0
RPS8	-1593	-1231.0
RPS9	-1107	-2477.0
S1PR1	2689	-1019.0
SAP18	4832	-868.0
SAP30	138	3914.0
SAP30L	-2519	-2301.0
SEC13	730	938.0
SEH1L	1085	4110.0
SFPQ	4544	4884.0
SH3GL1	-2937	2600.0
SH3KBP1	1014	-4274.0
SIGMAR1	-3608	1186.0
SKP1	2028	-1286.0
SLC25A4	-1327	-4427.0
SLC25A5	3467	4224.0
SNF8	-1018	-4338.0
SRC	-3910	3763.0
SSRP1	1755	1765.0
ST3GAL1	-4505	4494.0
ST3GAL2	-2316	-1550.0
ST3GAL3	-4844	-3253.0
ST3GAL4	-2946	4173.0
ST6GAL1	-5388	-301.0
ST6GALNAC2	-4576	3618.0
ST6GALNAC4	-4958	3575.0
STAM	3932	5249.0
STAM2	3489	4749.0
STAT2	-2601	-1249.0
STT3A	-1709	5319.0
STX1A	-411	1598.0
STX1B	-468	-2741.0
SUDS3	3840	-2556.0
SUGT1	3140	-4993.0
SUMO1	4213	-262.0
SUPT16H	3885	4417.0
SUPT4H1	3648	-1692.0
SUPT5H	1321	4377.0
SUZ12	3871	4598.0
TAF1	1708	4363.0
TAF10	-273	547.0
TAF11	2962	-1678.0
TAF12	3100	3716.0
TAF13	4749	1646.0
TAF2	4591	3536.0
TAF3	4294	4087.0
TAF4	-1340	4027.0
TAF4B	4967	5489.0
TAF5	4309	1473.0
TAF6	-912	-885.0
TAF7	4717	5281.0
TAF9B	1874	-618.0
TBK1	673	2827.0
TBL1XR1	1876	528.0
TBP	1137	3931.0
TCEA1	4037	163.0
TGFB1	-3111	4516.0
TPR	2984	275.0
TRIM27	4120	2963.0
TRIM28	4209	4779.0
TSG101	260	1656.0
TUBB	-3118	5321.0
TUSC3	70	2300.0
TXN	1855	4827.0
TXNRD1	-2444	4222.0
TYK2	-3123	725.0
UBAP1	-1913	5312.0
UBC	2672	3877.0
UBE2I	1246	733.0
UVRAG	3046	4601.0
VAMP1	-3322	-4793.0
VAMP2	-3293	-1899.0
VAV2	-4959	2847.0
VAV3	187	-276.0
VEGFA	-4571	-5070.0
VPS33B	1266	3131.0
VPS36	-3053	-2436.0
VPS37A	1868	1922.0
VPS37B	-3496	3692.0
VPS37C	1403	3199.0
VPS4A	-1545	-2729.0
VPS4B	4523	3841.0
VTA1	3283	591.0
WASF2	-4656	3026.0
WASF3	-1015	1293.0
WASL	2683	4511.0
WIPF1	-2552	2457.0
WIPF2	3299	-608.0
WIPF3	-5107	-4936.0
WNT5A	1837	-1443.0
XPO1	990	2133.0
XRCC4	-4731	333.0
XRCC5	4010	1456.0
XRCC6	3225	-2097.0
YES1	-176	-836.0
ZCRB1	833	-4058.0

---

---

Here is the session info with all the versions of packages used.

sessionInfo()

## R version 4.0.2 (2020-06-22)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 18.04.5 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.7.1
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.7.1
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.1.0               GGally_2.0.0               
##  [3] ggplot2_3.3.2               reshape2_1.4.4             
##  [5] beeswarm_0.2.3              gplots_3.1.0               
##  [7] gtools_3.8.2                tibble_3.0.4               
##  [9] dplyr_1.0.2                 echarts4r_0.3.3            
## [11] DESeq2_1.28.1               SummarizedExperiment_1.18.2
## [13] DelayedArray_0.14.1         matrixStats_0.57.0         
## [15] Biobase_2.48.0              GenomicRanges_1.40.0       
## [17] GenomeInfoDb_1.24.2         IRanges_2.22.2             
## [19] S4Vectors_0.26.1            BiocGenerics_0.34.0        
## [21] mitch_1.0.10               
## 
## loaded via a namespace (and not attached):
##  [1] bitops_1.0-6           bit64_4.0.5            RColorBrewer_1.1-2    
##  [4] rprojroot_1.3-2        tools_4.0.2            backports_1.1.10      
##  [7] R6_2.4.1               KernSmooth_2.23-17     DBI_1.1.0             
## [10] colorspace_1.4-1       withr_2.3.0            tidyselect_1.1.0      
## [13] gridExtra_2.3          bit_4.0.4              compiler_4.0.2        
## [16] desc_1.2.0             labeling_0.4.2         caTools_1.18.0        
## [19] scales_1.1.1           genefilter_1.70.0      stringr_1.4.0         
## [22] digest_0.6.26          rmarkdown_2.5          XVector_0.28.0        
## [25] pkgconfig_2.0.3        htmltools_0.5.0        highr_0.8             
## [28] fastmap_1.0.1          htmlwidgets_1.5.2      rlang_0.4.8           
## [31] RSQLite_2.2.1          shiny_1.5.0            generics_0.0.2        
## [34] farver_2.0.3           jsonlite_1.7.1         BiocParallel_1.22.0   
## [37] RCurl_1.98-1.2         magrittr_1.5           GenomeInfoDbData_1.2.3
## [40] Matrix_1.2-18          Rcpp_1.0.5             munsell_0.5.0         
## [43] lifecycle_0.2.0        stringi_1.5.3          yaml_2.2.1            
## [46] MASS_7.3-53            zlibbioc_1.34.0        plyr_1.8.6            
## [49] grid_4.0.2             blob_1.2.1             promises_1.1.1        
## [52] crayon_1.3.4           lattice_0.20-41        splines_4.0.2         
## [55] annotate_1.66.0        locfit_1.5-9.4         knitr_1.30            
## [58] pillar_1.4.6           geneplotter_1.66.0     XML_3.99-0.5          
## [61] glue_1.4.2             evaluate_0.14          vctrs_0.3.4           
## [64] httpuv_1.5.4           testthat_2.3.2         gtable_0.3.0          
## [67] purrr_0.3.4            reshape_0.8.8          assertthat_0.2.1      
## [70] xfun_0.18              mime_0.9               xtable_1.8-4          
## [73] later_1.1.0.1          survival_3.2-7         AnnotationDbi_1.50.3  
## [76] memoise_1.1.0          ellipsis_0.3.1

END of report