date generated: 2020-10-22

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

##             human      mouse
## A4GALT -14.988939  0.8182771
## AAAS    -2.435804  0.3877972
## AACS    -1.581711  4.1420212
## AAED1   -1.286093 -0.8848853
## AAGAB   -1.722220 -1.3839648
## AAK1    14.833940  0.4269837

Here are some metrics about the input data profile:

Profile metrics
Profile metrics
num_genes_in_profile 10654
duplicated_genes_present 0
num_profile_genes_in_sets 6218
num_profile_genes_not_in_sets 4436
profile_pearson_correl NaN
profile_spearman_correl 0.16715

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used: GMT file of genesets: ReactomePathways.gmt

Gene sets metrics
Gene sets metrics
num_genesets 2408
num_genesets_excluded 1175
num_genesets_included 1233

Gene sets by quadrant


Number of significant gene sets (FDR<0.05)= 411

Interactive enrichment scatterplot

All sets with FDR<0.05. Try hovering over the points.

Top N sets irrespective of FDR. Try hovering over the points.

A heatmap of S values for top results


A plot of effect size versus significance


Significance is the -log2(p.adjustMANOVA) and effect size is the s.dist which is the hypotenuse of the s scores.

Results table

Top N= 50 gene sets

set setSize pMANOVA p.adjustMANOVA s.dist s.human s.mouse p.human p.mouse
Metabolism of RNA 567 1.18e-61 1.46e-58 0.445 0.37000 0.2470 2.72e-50 2.90e-23
Processing of Capped Intron-Containing Pre-mRNA 212 7.36e-40 4.54e-37 0.569 0.50000 0.2720 5.18e-36 9.76e-12
mRNA Splicing - Major Pathway 161 1.60e-32 5.11e-30 0.590 0.50800 0.3000 1.02e-28 6.21e-11
mRNA Splicing 169 1.66e-32 5.11e-30 0.575 0.50100 0.2830 3.50e-29 2.56e-10
rRNA processing in the nucleus and cytosol 143 2.44e-22 6.01e-20 0.523 0.36700 0.3720 4.03e-14 1.75e-14
Major pathway of rRNA processing in the nucleolus and cytosol 134 2.69e-21 5.53e-19 0.527 0.35800 0.3860 8.79e-13 1.42e-14
Muscle contraction 120 4.80e-20 8.45e-18 0.518 -0.49300 -0.1570 1.12e-20 3.11e-03
Infectious disease 533 2.75e-19 4.24e-17 0.248 0.09130 0.2310 3.74e-04 2.14e-19
rRNA processing 154 3.77e-19 5.17e-17 0.465 0.33800 0.3190 4.82e-13 8.91e-12
The citric acid (TCA) cycle and respiratory electron transport 142 1.02e-18 1.26e-16 0.468 -0.20200 -0.4230 3.49e-05 3.92e-18
Gene expression (Transcription) 997 4.16e-18 4.67e-16 0.180 0.16600 0.0706 4.98e-18 2.37e-04
Metabolism 1377 1.63e-15 1.67e-13 0.148 -0.11500 -0.0931 4.70e-12 2.29e-08
rRNA modification in the nucleus and cytosol 52 3.48e-15 3.30e-13 0.698 0.60000 0.3560 7.07e-14 8.87e-06
Cell Cycle 484 4.05e-15 3.56e-13 0.234 0.19300 0.1340 7.18e-13 6.28e-07
Immune System 1225 1.08e-14 8.90e-13 0.135 -0.02410 0.1320 1.69e-01 4.10e-14
Signal Transduction 1401 1.83e-14 1.41e-12 0.121 -0.06420 0.1020 1.03e-04 6.07e-10
HIV Life Cycle 122 2.92e-14 2.12e-12 0.447 0.34900 0.2790 2.98e-11 1.14e-07
HIV Infection 187 5.00e-14 3.43e-12 0.360 0.24300 0.2650 1.09e-08 4.99e-10
Late Phase of HIV Life Cycle 112 8.01e-14 5.20e-12 0.458 0.35900 0.2850 5.75e-11 1.98e-07
Nervous system development 395 3.49e-13 2.15e-11 0.205 -0.11700 0.1690 7.65e-05 1.19e-08
Innate Immune System 608 4.07e-13 2.39e-11 0.173 -0.04310 0.1670 7.38e-02 4.06e-12
Cytokine Signaling in Immune system 518 5.88e-13 3.30e-11 0.188 -0.02750 0.1860 2.91e-01 8.82e-13
Influenza Infection 107 7.65e-13 4.10e-11 0.440 0.16900 0.4060 2.56e-03 4.47e-13
Extracellular matrix organization 194 1.08e-12 5.56e-11 0.287 -0.25300 0.1340 1.41e-09 1.31e-03
Transport of Mature Transcript to Cytoplasm 69 1.18e-12 5.82e-11 0.549 0.48000 0.2670 5.44e-12 1.28e-04
Transport of Mature mRNA derived from an Intron-Containing Transcript 60 2.20e-12 1.04e-10 0.579 0.52000 0.2540 3.24e-12 6.83e-04
Cell Cycle, Mitotic 397 2.27e-12 1.04e-10 0.233 0.18200 0.1440 6.23e-10 9.94e-07
RNA Polymerase II Pre-transcription Events 69 6.37e-12 2.80e-10 0.538 0.43200 0.3200 5.54e-10 4.29e-06
RNA Polymerase II Transcription 889 6.76e-12 2.87e-10 0.153 0.13800 0.0665 8.38e-12 1.00e-03
Disease 1013 1.15e-11 4.71e-10 0.135 0.00755 0.1340 6.92e-01 1.74e-12
Pyruvate metabolism and Citric Acid (TCA) cycle 49 1.25e-11 4.99e-10 0.618 -0.26300 -0.5590 1.45e-03 1.28e-11
Signaling by Interleukins 278 2.95e-11 1.14e-09 0.232 -0.05420 0.2260 1.23e-01 1.24e-10
Axon guidance 378 4.45e-11 1.66e-09 0.192 -0.10300 0.1620 6.49e-04 9.05e-08
Neutrophil degranulation 292 1.03e-10 3.71e-09 0.219 -0.06070 0.2110 7.65e-02 7.43e-10
Cardiac conduction 63 1.05e-10 3.71e-09 0.528 -0.44900 -0.2780 7.15e-10 1.40e-04
SRP-dependent cotranslational protein targeting to membrane 74 1.60e-10 5.47e-09 0.462 0.09680 0.4510 1.51e-01 1.96e-11
Metabolism of non-coding RNA 45 2.20e-10 7.14e-09 0.604 0.55600 0.2360 1.10e-10 6.24e-03
snRNP Assembly 45 2.20e-10 7.14e-09 0.604 0.55600 0.2360 1.10e-10 6.24e-03
Developmental Biology 588 2.95e-10 9.33e-09 0.150 -0.07060 0.1320 3.97e-03 6.77e-08
Cellular responses to external stimuli 410 3.29e-10 9.94e-09 0.198 0.04990 0.1910 8.62e-02 4.74e-11
Transcription of the HIV genome 59 3.31e-10 9.94e-09 0.535 0.43600 0.3100 7.27e-09 3.94e-05
Influenza Viral RNA Transcription and Replication 91 3.68e-10 1.08e-08 0.420 0.15700 0.3890 9.98e-03 1.44e-10
Cellular responses to stress 406 4.76e-10 1.36e-08 0.197 0.04900 0.1900 9.36e-02 6.79e-11
Response of EIF2AK4 (GCN2) to amino acid deficiency 63 6.94e-10 1.94e-08 0.462 -0.03120 0.4610 6.69e-01 2.66e-10
Cell Cycle Checkpoints 191 8.03e-10 2.20e-08 0.294 0.21900 0.1970 2.07e-07 2.98e-06
Respiratory electron transport 92 1.45e-09 3.89e-08 0.408 -0.17800 -0.3670 3.30e-03 1.26e-09
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. 96 1.52e-09 3.99e-08 0.399 -0.17600 -0.3580 2.89e-03 1.44e-09
Hemostasis 349 3.13e-09 8.04e-08 0.180 -0.14100 0.1110 7.12e-06 3.96e-04
Interleukin-4 and Interleukin-13 signaling 64 4.62e-09 1.16e-07 0.422 -0.13000 0.4010 7.24e-02 2.96e-08
Peptide chain elongation 53 5.61e-09 1.38e-07 0.472 -0.06860 0.4670 3.88e-01 4.29e-09


Results (complete table)


Click HERE to show results for all gene sets

Complete results
set setSize pMANOVA p.adjustMANOVA s.dist s.human s.mouse p.human p.mouse
Metabolism of RNA 567 1.18e-61 1.46e-58 0.44500 0.370000 0.247000 2.72e-50 2.90e-23
Processing of Capped Intron-Containing Pre-mRNA 212 7.36e-40 4.54e-37 0.56900 0.500000 0.272000 5.18e-36 9.76e-12
mRNA Splicing - Major Pathway 161 1.60e-32 5.11e-30 0.59000 0.508000 0.300000 1.02e-28 6.21e-11
mRNA Splicing 169 1.66e-32 5.11e-30 0.57500 0.501000 0.283000 3.50e-29 2.56e-10
rRNA processing in the nucleus and cytosol 143 2.44e-22 6.01e-20 0.52300 0.367000 0.372000 4.03e-14 1.75e-14
Major pathway of rRNA processing in the nucleolus and cytosol 134 2.69e-21 5.53e-19 0.52700 0.358000 0.386000 8.79e-13 1.42e-14
Muscle contraction 120 4.80e-20 8.45e-18 0.51800 -0.493000 -0.157000 1.12e-20 3.11e-03
Infectious disease 533 2.75e-19 4.24e-17 0.24800 0.091300 0.231000 3.74e-04 2.14e-19
rRNA processing 154 3.77e-19 5.17e-17 0.46500 0.338000 0.319000 4.82e-13 8.91e-12
The citric acid (TCA) cycle and respiratory electron transport 142 1.02e-18 1.26e-16 0.46800 -0.202000 -0.423000 3.49e-05 3.92e-18
Gene expression (Transcription) 997 4.16e-18 4.67e-16 0.18000 0.166000 0.070600 4.98e-18 2.37e-04
Metabolism 1377 1.63e-15 1.67e-13 0.14800 -0.115000 -0.093100 4.70e-12 2.29e-08
rRNA modification in the nucleus and cytosol 52 3.48e-15 3.30e-13 0.69800 0.600000 0.356000 7.07e-14 8.87e-06
Cell Cycle 484 4.05e-15 3.56e-13 0.23400 0.193000 0.134000 7.18e-13 6.28e-07
Immune System 1225 1.08e-14 8.90e-13 0.13500 -0.024100 0.132000 1.69e-01 4.10e-14
Signal Transduction 1401 1.83e-14 1.41e-12 0.12100 -0.064200 0.102000 1.03e-04 6.07e-10
HIV Life Cycle 122 2.92e-14 2.12e-12 0.44700 0.349000 0.279000 2.98e-11 1.14e-07
HIV Infection 187 5.00e-14 3.43e-12 0.36000 0.243000 0.265000 1.09e-08 4.99e-10
Late Phase of HIV Life Cycle 112 8.01e-14 5.20e-12 0.45800 0.359000 0.285000 5.75e-11 1.98e-07
Nervous system development 395 3.49e-13 2.15e-11 0.20500 -0.117000 0.169000 7.65e-05 1.19e-08
Innate Immune System 608 4.07e-13 2.39e-11 0.17300 -0.043100 0.167000 7.38e-02 4.06e-12
Cytokine Signaling in Immune system 518 5.88e-13 3.30e-11 0.18800 -0.027500 0.186000 2.91e-01 8.82e-13
Influenza Infection 107 7.65e-13 4.10e-11 0.44000 0.169000 0.406000 2.56e-03 4.47e-13
Extracellular matrix organization 194 1.08e-12 5.56e-11 0.28700 -0.253000 0.134000 1.41e-09 1.31e-03
Transport of Mature Transcript to Cytoplasm 69 1.18e-12 5.82e-11 0.54900 0.480000 0.267000 5.44e-12 1.28e-04
Transport of Mature mRNA derived from an Intron-Containing Transcript 60 2.20e-12 1.04e-10 0.57900 0.520000 0.254000 3.24e-12 6.83e-04
Cell Cycle, Mitotic 397 2.27e-12 1.04e-10 0.23300 0.182000 0.144000 6.23e-10 9.94e-07
RNA Polymerase II Pre-transcription Events 69 6.37e-12 2.80e-10 0.53800 0.432000 0.320000 5.54e-10 4.29e-06
RNA Polymerase II Transcription 889 6.76e-12 2.87e-10 0.15300 0.138000 0.066500 8.38e-12 1.00e-03
Disease 1013 1.15e-11 4.71e-10 0.13500 0.007550 0.134000 6.92e-01 1.74e-12
Pyruvate metabolism and Citric Acid (TCA) cycle 49 1.25e-11 4.99e-10 0.61800 -0.263000 -0.559000 1.45e-03 1.28e-11
Signaling by Interleukins 278 2.95e-11 1.14e-09 0.23200 -0.054200 0.226000 1.23e-01 1.24e-10
Axon guidance 378 4.45e-11 1.66e-09 0.19200 -0.103000 0.162000 6.49e-04 9.05e-08
Neutrophil degranulation 292 1.03e-10 3.71e-09 0.21900 -0.060700 0.211000 7.65e-02 7.43e-10
Cardiac conduction 63 1.05e-10 3.71e-09 0.52800 -0.449000 -0.278000 7.15e-10 1.40e-04
SRP-dependent cotranslational protein targeting to membrane 74 1.60e-10 5.47e-09 0.46200 0.096800 0.451000 1.51e-01 1.96e-11
Metabolism of non-coding RNA 45 2.20e-10 7.14e-09 0.60400 0.556000 0.236000 1.10e-10 6.24e-03
snRNP Assembly 45 2.20e-10 7.14e-09 0.60400 0.556000 0.236000 1.10e-10 6.24e-03
Developmental Biology 588 2.95e-10 9.33e-09 0.15000 -0.070600 0.132000 3.97e-03 6.77e-08
Cellular responses to external stimuli 410 3.29e-10 9.94e-09 0.19800 0.049900 0.191000 8.62e-02 4.74e-11
Transcription of the HIV genome 59 3.31e-10 9.94e-09 0.53500 0.436000 0.310000 7.27e-09 3.94e-05
Influenza Viral RNA Transcription and Replication 91 3.68e-10 1.08e-08 0.42000 0.157000 0.389000 9.98e-03 1.44e-10
Cellular responses to stress 406 4.76e-10 1.36e-08 0.19700 0.049000 0.190000 9.36e-02 6.79e-11
Response of EIF2AK4 (GCN2) to amino acid deficiency 63 6.94e-10 1.94e-08 0.46200 -0.031200 0.461000 6.69e-01 2.66e-10
Cell Cycle Checkpoints 191 8.03e-10 2.20e-08 0.29400 0.219000 0.197000 2.07e-07 2.98e-06
Respiratory electron transport 92 1.45e-09 3.89e-08 0.40800 -0.178000 -0.367000 3.30e-03 1.26e-09
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. 96 1.52e-09 3.99e-08 0.39900 -0.176000 -0.358000 2.89e-03 1.44e-09
Hemostasis 349 3.13e-09 8.04e-08 0.18000 -0.141000 0.111000 7.12e-06 3.96e-04
Interleukin-4 and Interleukin-13 signaling 64 4.62e-09 1.16e-07 0.42200 -0.130000 0.401000 7.24e-02 2.96e-08
Peptide chain elongation 53 5.61e-09 1.38e-07 0.47200 -0.068600 0.467000 3.88e-01 4.29e-09
Signaling by GPCR 270 6.17e-09 1.49e-07 0.21200 -0.211000 0.020900 2.92e-09 5.57e-01
RNA Polymerase II Transcription Termination 57 6.73e-09 1.60e-07 0.50500 0.408000 0.298000 1.02e-07 9.96e-05
Mitochondrial translation 87 7.14e-09 1.66e-07 0.35200 0.158000 -0.314000 1.08e-02 4.14e-07
Eukaryotic Translation Elongation 56 9.22e-09 2.08e-07 0.44900 -0.088300 0.441000 2.54e-01 1.20e-08
Selenocysteine synthesis 56 9.29e-09 2.08e-07 0.45900 -0.030100 0.458000 6.97e-01 3.24e-09
M Phase 275 9.43e-09 2.08e-07 0.22900 0.195000 0.120000 3.05e-08 6.90e-04
Fatty acid metabolism 102 1.05e-08 2.26e-07 0.37400 -0.222000 -0.301000 1.08e-04 1.57e-07
Selenoamino acid metabolism 68 1.24e-08 2.65e-07 0.41500 -0.013500 0.415000 8.48e-01 3.35e-09
tRNA processing 98 1.89e-08 3.94e-07 0.36100 0.347000 0.100000 3.23e-09 8.80e-02
GTP hydrolysis and joining of the 60S ribosomal subunit 73 2.64e-08 5.42e-07 0.40700 0.076100 0.400000 2.62e-01 3.50e-09
Viral mRNA Translation 53 3.28e-08 6.62e-07 0.45100 -0.055000 0.447000 4.89e-01 1.78e-08
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 57 3.41e-08 6.78e-07 0.44000 -0.018700 0.440000 8.08e-01 9.70e-09
Mitotic Anaphase 171 3.82e-08 7.37e-07 0.28100 0.203000 0.194000 4.97e-06 1.32e-05
Mitotic Metaphase and Anaphase 171 3.82e-08 7.37e-07 0.28100 0.203000 0.194000 4.97e-06 1.32e-05
Formation of a pool of free 40S subunits 63 4.28e-08 8.12e-07 0.42200 0.016800 0.421000 8.18e-01 7.58e-09
RNA polymerase II transcribes snRNA genes 67 5.38e-08 1.00e-06 0.43400 0.386000 0.198000 4.77e-08 5.14e-03
L13a-mediated translational silencing of Ceruloplasmin expression 71 5.70e-08 1.02e-06 0.40100 0.059200 0.397000 3.90e-01 7.70e-09
mRNA 3'-end processing 49 5.72e-08 1.02e-06 0.51300 0.417000 0.298000 4.52e-07 3.06e-04
Striated Muscle Contraction 30 5.73e-08 1.02e-06 0.63100 -0.603000 -0.187000 1.10e-08 7.60e-02
Eukaryotic Translation Termination 55 6.49e-08 1.14e-06 0.43500 -0.048000 0.432000 5.39e-01 3.08e-08
GPCR downstream signalling 245 6.85e-08 1.19e-06 0.20800 -0.207000 0.017800 2.64e-08 6.33e-01
Mitochondrial Fatty Acid Beta-Oxidation 30 8.79e-08 1.51e-06 0.64300 -0.336000 -0.548000 1.48e-03 2.05e-07
Metabolism of proteins 1402 8.94e-08 1.51e-06 0.10200 0.078400 0.064600 2.12e-06 9.45e-05
Mitochondrial translation elongation 81 1.07e-07 1.74e-06 0.33700 0.158000 -0.297000 1.39e-02 3.87e-06
Cap-dependent Translation Initiation 79 1.07e-07 1.74e-06 0.37500 0.068100 0.369000 2.96e-01 1.48e-08
Eukaryotic Translation Initiation 79 1.07e-07 1.74e-06 0.37500 0.068100 0.369000 2.96e-01 1.48e-08
Regulation of HSF1-mediated heat shock response 65 1.13e-07 1.81e-06 0.43600 0.361000 0.244000 4.99e-07 6.87e-04
SUMOylation of DNA replication proteins 35 1.17e-07 1.85e-06 0.59100 0.499000 0.316000 3.30e-07 1.21e-03
RHO GTPase Effectors 173 1.37e-07 2.14e-06 0.25700 0.071600 0.247000 1.06e-01 2.43e-08
HIV Transcription Initiation 40 1.50e-07 2.17e-06 0.55000 0.452000 0.313000 7.48e-07 6.22e-04
RNA Polymerase II HIV Promoter Escape 40 1.50e-07 2.17e-06 0.55000 0.452000 0.313000 7.48e-07 6.22e-04
RNA Polymerase II Promoter Escape 40 1.50e-07 2.17e-06 0.55000 0.452000 0.313000 7.48e-07 6.22e-04
RNA Polymerase II Transcription Initiation 40 1.50e-07 2.17e-06 0.55000 0.452000 0.313000 7.48e-07 6.22e-04
RNA Polymerase II Transcription Initiation And Promoter Clearance 40 1.50e-07 2.17e-06 0.55000 0.452000 0.313000 7.48e-07 6.22e-04
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 40 1.50e-07 2.17e-06 0.55000 0.452000 0.313000 7.48e-07 6.22e-04
Mitochondrial translation termination 81 1.69e-07 2.43e-06 0.33200 0.156000 -0.293000 1.54e-02 5.28e-06
Signaling by Receptor Tyrosine Kinases 357 1.77e-07 2.51e-06 0.16400 -0.046200 0.157000 1.37e-01 4.42e-07
Transport of the SLBP Dependant Mature mRNA 29 1.89e-07 2.65e-06 0.63500 0.556000 0.307000 2.20e-07 4.19e-03
tRNA processing in the nucleus 48 2.34e-07 3.24e-06 0.48600 0.445000 0.195000 1.00e-07 1.93e-02
Mitochondrial translation initiation 81 2.64e-07 3.61e-06 0.32800 0.152000 -0.290000 1.86e-02 6.47e-06
Host Interactions of HIV factors 102 3.58e-07 4.85e-06 0.33500 0.178000 0.283000 1.91e-03 8.14e-07
Post-chaperonin tubulin folding pathway 15 4.53e-07 6.03e-06 0.73600 -0.483000 0.555000 1.21e-03 1.96e-04
SUMOylation of ubiquitinylation proteins 31 4.54e-07 6.03e-06 0.59500 0.530000 0.270000 3.33e-07 9.22e-03
Transport of the SLBP independent Mature mRNA 28 4.83e-07 6.33e-06 0.62500 0.556000 0.285000 3.58e-07 9.15e-03
Regulation of expression of SLITs and ROBOs 114 5.73e-07 7.44e-06 0.29200 0.025900 0.290000 6.33e-01 9.05e-08
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 75 6.05e-07 7.69e-06 0.36400 0.065700 0.358000 3.26e-01 8.76e-08
Nonsense-Mediated Decay (NMD) 75 6.05e-07 7.69e-06 0.36400 0.065700 0.358000 3.26e-01 8.76e-08
Transport of Mature mRNAs Derived from Intronless Transcripts 36 6.14e-07 7.69e-06 0.55100 0.468000 0.290000 1.16e-06 2.62e-03
mRNA Splicing - Minor Pathway 47 6.18e-07 7.69e-06 0.48400 0.398000 0.275000 2.33e-06 1.11e-03
Viral Messenger RNA Synthesis 35 9.00e-07 1.11e-05 0.55200 0.466000 0.295000 1.85e-06 2.53e-03
Resolution of Sister Chromatid Cohesion 66 9.30e-07 1.14e-05 0.39500 0.362000 0.157000 3.63e-07 2.74e-02
Cell surface interactions at the vascular wall 72 1.01e-06 1.22e-05 0.32800 -0.264000 0.195000 1.11e-04 4.20e-03
Complex I biogenesis 52 1.03e-06 1.23e-05 0.44600 -0.196000 -0.400000 1.45e-02 6.02e-07
Ion homeostasis 37 1.06e-06 1.26e-05 0.53500 -0.442000 -0.301000 3.30e-06 1.54e-03
Formation of RNA Pol II elongation complex 50 1.13e-06 1.31e-05 0.46000 0.371000 0.273000 5.81e-06 8.58e-04
RNA Polymerase II Transcription Elongation 50 1.13e-06 1.31e-05 0.46000 0.371000 0.273000 5.81e-06 8.58e-04
Signaling by ROBO receptors 151 1.15e-06 1.33e-05 0.24000 -0.021000 0.239000 6.58e-01 4.13e-07
Transport of Mature mRNA Derived from an Intronless Transcript 35 1.55e-06 1.77e-05 0.53900 0.466000 0.271000 1.87e-06 5.50e-03
SUMOylation of RNA binding proteins 38 1.63e-06 1.84e-05 0.51500 0.452000 0.247000 1.46e-06 8.38e-03
Interactions of Rev with host cellular proteins 29 1.74e-06 1.95e-05 0.59200 0.499000 0.318000 3.39e-06 3.02e-03
Signaling by Rho GTPases 269 1.99e-06 2.21e-05 0.18000 0.000260 0.180000 9.94e-01 4.35e-07
Postmitotic nuclear pore complex (NPC) reformation 24 2.04e-06 2.25e-05 0.64600 0.543000 0.350000 4.11e-06 2.97e-03
Formation of tubulin folding intermediates by CCT/TriC 17 2.18e-06 2.38e-05 0.69000 -0.095200 0.683000 4.97e-01 1.08e-06
SUMOylation of SUMOylation proteins 27 2.26e-06 2.45e-05 0.59900 0.542000 0.254000 1.08e-06 2.26e-02
Mitochondrial biogenesis 66 2.33e-06 2.50e-05 0.37000 -0.071200 -0.363000 3.18e-01 3.57e-07
Smooth Muscle Contraction 32 2.37e-06 2.52e-05 0.49200 -0.474000 0.133000 3.58e-06 1.94e-01
Separation of Sister Chromatids 125 2.42e-06 2.55e-05 0.28200 0.242000 0.145000 3.23e-06 5.19e-03
Export of Viral Ribonucleoproteins from Nucleus 26 2.73e-06 2.85e-05 0.60800 0.542000 0.275000 1.69e-06 1.54e-02
DNA Repair 242 3.07e-06 3.18e-05 0.19800 0.184000 0.072600 9.08e-07 5.32e-02
Transport of small molecules 410 3.29e-06 3.38e-05 0.15500 -0.136000 -0.075700 2.99e-06 9.20e-03
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 57 3.67e-06 3.71e-05 0.40900 0.353000 0.206000 4.05e-06 7.19e-03
Amplification of signal from the kinetochores 57 3.67e-06 3.71e-05 0.40900 0.353000 0.206000 4.05e-06 7.19e-03
Nuclear import of Rev protein 26 3.89e-06 3.90e-05 0.60000 0.533000 0.275000 2.52e-06 1.53e-02
Neuronal System 174 4.06e-06 4.03e-05 0.21600 -0.216000 0.001900 9.32e-07 9.66e-01
RHO GTPases Activate Formins 80 4.18e-06 4.11e-05 0.34800 0.222000 0.267000 6.01e-04 3.69e-05
Interferon Signaling 120 4.20e-06 4.11e-05 0.28100 0.140000 0.244000 8.42e-03 4.19e-06
Rev-mediated nuclear export of HIV RNA 28 4.91e-06 4.76e-05 0.57700 0.490000 0.306000 7.25e-06 5.14e-03
Chromosome Maintenance 68 5.02e-06 4.81e-05 0.37300 0.301000 0.221000 1.85e-05 1.67e-03
Transport of Ribonucleoproteins into the Host Nucleus 25 5.04e-06 4.81e-05 0.60500 0.541000 0.270000 2.84e-06 1.97e-02
Protein localization 136 5.46e-06 5.18e-05 0.24900 -0.045800 -0.245000 3.58e-01 8.56e-07
Mitotic Prometaphase 137 5.66e-06 5.31e-05 0.25200 0.242000 0.071500 1.09e-06 1.50e-01
G2/M Checkpoints 106 5.68e-06 5.31e-05 0.29700 0.171000 0.243000 2.38e-03 1.59e-05
Epigenetic regulation of gene expression 79 5.97e-06 5.53e-05 0.34400 0.279000 0.201000 1.92e-05 2.03e-03
Citric acid cycle (TCA cycle) 21 7.05e-06 6.48e-05 0.64400 -0.243000 -0.597000 5.39e-02 2.22e-06
Cellular response to heat stress 82 7.91e-06 7.22e-05 0.33500 0.231000 0.243000 3.15e-04 1.46e-04
NS1 Mediated Effects on Host Pathways 31 8.85e-06 8.00e-05 0.53600 0.451000 0.289000 1.37e-05 5.35e-03
Interleukin-10 signaling 11 8.92e-06 8.00e-05 0.78900 -0.252000 0.747000 1.48e-01 1.76e-05
Interactions of Vpr with host cellular proteins 29 8.96e-06 8.00e-05 0.55200 0.476000 0.280000 9.21e-06 9.20e-03
EML4 and NUDC in mitotic spindle formation 61 9.56e-06 8.48e-05 0.38100 0.326000 0.197000 1.10e-05 8.01e-03
Gluconeogenesis 23 9.76e-06 8.60e-05 0.61700 -0.535000 -0.306000 8.82e-06 1.11e-02
Vpr-mediated nuclear import of PICs 27 9.98e-06 8.73e-05 0.56900 0.492000 0.286000 9.70e-06 1.01e-02
Pyruvate metabolism 26 1.13e-05 9.82e-05 0.56900 -0.228000 -0.522000 4.43e-02 4.16e-06
NEP/NS2 Interacts with the Cellular Export Machinery 25 1.26e-05 1.09e-04 0.58000 0.525000 0.245000 5.54e-06 3.38e-02
NGF-stimulated transcription 32 1.29e-05 1.11e-04 0.47000 -0.050900 0.467000 6.19e-01 4.91e-06
G alpha (i) signalling events 127 1.32e-05 1.12e-04 0.23300 -0.228000 0.049500 1.01e-05 3.37e-01
Degradation of the extracellular matrix 58 1.51e-05 1.27e-04 0.33200 -0.301000 0.141000 7.56e-05 6.32e-02
Unfolded Protein Response (UPR) 82 1.52e-05 1.27e-04 0.31700 0.127000 0.291000 4.74e-02 5.52e-06
Regulation of TP53 Activity 134 1.61e-05 1.34e-04 0.24800 0.229000 0.094600 5.16e-06 5.94e-02
Transcriptional regulation by small RNAs 39 1.90e-05 1.58e-04 0.45800 0.406000 0.214000 1.19e-05 2.11e-02
Negative epigenetic regulation of rRNA expression 43 1.94e-05 1.60e-04 0.43500 0.388000 0.197000 1.06e-05 2.58e-02
Mitotic Spindle Checkpoint 74 1.96e-05 1.60e-04 0.33000 0.302000 0.134000 7.42e-06 4.60e-02
Antiviral mechanism by IFN-stimulated genes 64 2.08e-05 1.69e-04 0.36200 0.282000 0.227000 9.80e-05 1.69e-03
Regulation of actin dynamics for phagocytic cup formation 49 2.16e-05 1.73e-04 0.37400 -0.022700 0.373000 7.84e-01 6.29e-06
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 23 2.17e-05 1.73e-04 0.58800 0.538000 0.235000 7.84e-06 5.09e-02
Regulation of Glucokinase by Glucokinase Regulatory Protein 23 2.17e-05 1.73e-04 0.58800 0.538000 0.235000 7.84e-06 5.09e-02
Mitochondrial tRNA aminoacylation 18 2.34e-05 1.85e-04 0.59200 0.178000 -0.565000 1.90e-01 3.38e-05
SLC-mediated transmembrane transport 120 2.65e-05 2.08e-04 0.23600 -0.234000 0.024900 9.69e-06 6.39e-01
HCMV Early Events 50 3.16e-05 2.43e-04 0.39000 0.363000 0.144000 9.30e-06 7.80e-02
FCGR3A-mediated phagocytosis 47 3.18e-05 2.43e-04 0.37700 -0.012200 0.376000 8.86e-01 8.17e-06
Leishmania phagocytosis 47 3.18e-05 2.43e-04 0.37700 -0.012200 0.376000 8.86e-01 8.17e-06
Parasite infection 47 3.18e-05 2.43e-04 0.37700 -0.012200 0.376000 8.86e-01 8.17e-06
EPH-Ephrin signaling 75 3.33e-05 2.53e-04 0.28600 -0.083500 0.274000 2.12e-01 4.21e-05
DNA Replication 111 3.35e-05 2.53e-04 0.26800 0.153000 0.220000 5.43e-03 6.28e-05
SUMOylation of DNA damage response and repair proteins 62 3.80e-05 2.86e-04 0.35000 0.318000 0.146000 1.51e-05 4.76e-02
Telomere Maintenance 56 3.82e-05 2.86e-04 0.37600 0.293000 0.235000 1.51e-04 2.34e-03
Signaling by NTRKs 113 4.09e-05 3.04e-04 0.22800 -0.091600 0.209000 9.34e-02 1.28e-04
G1/S Transition 112 4.45e-05 3.29e-04 0.26100 0.127000 0.228000 2.07e-02 3.12e-05
Gene Silencing by RNA 54 4.50e-05 3.30e-04 0.35700 0.352000 0.058800 7.67e-06 4.55e-01
Transcriptional activation of mitochondrial biogenesis 47 5.05e-05 3.69e-04 0.37800 -0.045300 -0.375000 5.91e-01 8.86e-06
EGR2 and SOX10-mediated initiation of Schwann cell myelination 20 5.36e-05 3.89e-04 0.52500 -0.423000 0.310000 1.07e-03 1.63e-02
Mitotic G1 phase and G1/S transition 127 5.57e-05 4.01e-04 0.24100 0.099800 0.219000 5.29e-02 2.16e-05
Nuclear Envelope (NE) Reassembly 59 5.73e-05 4.11e-04 0.35500 0.173000 0.309000 2.15e-02 4.04e-05
Interleukin-1 family signaling 102 6.51e-05 4.64e-04 0.25500 0.040000 0.252000 4.86e-01 1.13e-05
Phase 0 - rapid depolarisation 18 6.59e-05 4.67e-04 0.62800 -0.579000 -0.242000 2.11e-05 7.58e-02
Synthesis of DNA 106 6.72e-05 4.72e-04 0.26500 0.147000 0.221000 9.33e-03 9.10e-05
Generic Transcription Pathway 780 6.74e-05 4.72e-04 0.09870 0.091400 0.037200 2.06e-05 8.31e-02
Mitotic Prophase 70 7.75e-05 5.36e-04 0.32200 0.273000 0.171000 7.92e-05 1.37e-02
Collagen biosynthesis and modifying enzymes 48 7.75e-05 5.36e-04 0.34300 -0.330000 0.095600 7.91e-05 2.53e-01
Collagen formation 64 7.78e-05 5.36e-04 0.30000 -0.293000 0.065200 5.24e-05 3.67e-01
Nuclear Receptor transcription pathway 38 7.86e-05 5.39e-04 0.43900 -0.353000 -0.261000 1.70e-04 5.45e-03
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 24 8.87e-05 6.03e-04 0.51400 0.067500 0.509000 5.67e-01 1.58e-05
TP53 Regulates Transcription of DNA Repair Genes 51 8.90e-05 6.03e-04 0.37300 0.322000 0.188000 6.89e-05 2.05e-02
Ribosomal scanning and start codon recognition 45 9.38e-05 6.32e-04 0.38600 0.125000 0.366000 1.47e-01 2.23e-05
Semaphorin interactions 54 9.63e-05 6.46e-04 0.31000 -0.186000 0.248000 1.81e-02 1.65e-03
S Phase 144 1.19e-04 7.94e-04 0.22200 0.143000 0.170000 3.17e-03 4.49e-04
Regulation of pyruvate dehydrogenase (PDH) complex 15 1.21e-04 8.00e-04 0.65100 -0.162000 -0.631000 2.77e-01 2.33e-05
NoRC negatively regulates rRNA expression 40 1.23e-04 8.11e-04 0.41100 0.366000 0.187000 6.13e-05 4.10e-02
ISG15 antiviral mechanism 59 1.25e-04 8.19e-04 0.34400 0.271000 0.213000 3.29e-04 4.79e-03
Prefoldin mediated transfer of substrate to CCT/TriC 22 1.28e-04 8.35e-04 0.53500 0.124000 0.520000 3.16e-01 2.42e-05
Platelet activation, signaling and aggregation 169 1.29e-04 8.35e-04 0.17400 -0.093600 0.147000 3.65e-02 1.05e-03
SUMOylation 137 1.35e-04 8.72e-04 0.22000 0.203000 0.086500 4.46e-05 8.16e-02
Processing of DNA double-strand break ends 50 1.40e-04 8.93e-04 0.37100 0.295000 0.226000 3.18e-04 5.80e-03
Metabolism of water-soluble vitamins and cofactors 89 1.40e-04 8.93e-04 0.25900 -0.021800 -0.258000 7.23e-01 2.69e-05
Transcriptional Regulation by TP53 307 1.42e-04 9.04e-04 0.15100 0.125000 0.084300 1.81e-04 1.17e-02
Pausing and recovery of Tat-mediated HIV elongation 25 1.57e-04 9.89e-04 0.52000 0.300000 0.424000 9.46e-03 2.42e-04
Tat-mediated HIV elongation arrest and recovery 25 1.57e-04 9.89e-04 0.52000 0.300000 0.424000 9.46e-03 2.42e-04
Post-translational protein modification 1001 1.75e-04 1.09e-03 0.08610 0.059700 0.062100 1.84e-03 1.20e-03
Formation of HIV elongation complex in the absence of HIV Tat 38 1.84e-04 1.14e-03 0.41900 0.331000 0.257000 4.16e-04 6.22e-03
Metabolism of carbohydrates 205 1.85e-04 1.14e-03 0.16000 -0.154000 0.041500 1.49e-04 3.09e-01
Translation initiation complex formation 44 1.96e-04 1.21e-03 0.37500 0.119000 0.355000 1.74e-01 4.61e-05
RHO GTPases Activate WASPs and WAVEs 31 2.07e-04 1.27e-03 0.43700 0.090300 0.427000 3.85e-01 3.88e-05
Branched-chain amino acid catabolism 20 2.10e-04 1.28e-03 0.53700 -0.074400 -0.531000 5.65e-01 3.89e-05
Stimuli-sensing channels 43 2.20e-04 1.34e-03 0.39100 -0.270000 -0.283000 2.23e-03 1.33e-03
Signaling by NTRK1 (TRKA) 97 2.24e-04 1.35e-03 0.22600 -0.080800 0.211000 1.70e-01 3.45e-04
Formation of the ternary complex, and subsequently, the 43S complex 38 2.25e-04 1.35e-03 0.39500 0.096900 0.383000 3.02e-01 4.45e-05
Formation of HIV-1 elongation complex containing HIV-1 Tat 36 2.28e-04 1.35e-03 0.42600 0.307000 0.296000 1.45e-03 2.14e-03
HIV Transcription Elongation 36 2.28e-04 1.35e-03 0.42600 0.307000 0.296000 1.45e-03 2.14e-03
Tat-mediated elongation of the HIV-1 transcript 36 2.28e-04 1.35e-03 0.42600 0.307000 0.296000 1.45e-03 2.14e-03
Organelle biogenesis and maintenance 224 2.31e-04 1.36e-03 0.14800 0.059500 -0.136000 1.27e-01 4.86e-04
Transport of inorganic cations/anions and amino acids/oligopeptides 56 2.32e-04 1.36e-03 0.32500 -0.315000 -0.077500 4.54e-05 3.17e-01
HIV elongation arrest and recovery 27 2.35e-04 1.36e-03 0.49100 0.334000 0.360000 2.64e-03 1.22e-03
Pausing and recovery of HIV elongation 27 2.35e-04 1.36e-03 0.49100 0.334000 0.360000 2.64e-03 1.22e-03
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 45 2.48e-04 1.43e-03 0.36500 0.113000 0.347000 1.91e-01 5.73e-05
SUMOylation of chromatin organization proteins 46 2.49e-04 1.43e-03 0.36700 0.333000 0.155000 9.66e-05 6.95e-02
tRNA Aminoacylation 24 2.65e-04 1.52e-03 0.44500 0.184000 -0.405000 1.18e-01 5.99e-04
Potassium Channels 34 2.77e-04 1.58e-03 0.43300 -0.334000 -0.275000 7.53e-04 5.54e-03
Nuclear Pore Complex (NPC) Disassembly 27 2.93e-04 1.67e-03 0.47500 0.427000 0.207000 1.24e-04 6.27e-02
Glycosaminoglycan metabolism 81 2.96e-04 1.67e-03 0.23700 -0.153000 0.181000 1.77e-02 4.84e-03
Programmed Cell Death 145 3.03e-04 1.71e-03 0.18300 -0.052200 0.176000 2.80e-01 2.71e-04
Glyoxylate metabolism and glycine degradation 20 3.14e-04 1.76e-03 0.54000 -0.172000 -0.511000 1.83e-01 7.54e-05
Regulation of mRNA stability by proteins that bind AU-rich elements 75 3.17e-04 1.77e-03 0.28700 0.150000 0.245000 2.51e-02 2.54e-04
IRE1alpha activates chaperones 47 3.37e-04 1.87e-03 0.33500 0.012300 0.335000 8.84e-01 7.36e-05
Regulation of TP53 Activity through Phosphorylation 74 3.52e-04 1.95e-03 0.28600 0.248000 0.144000 2.37e-04 3.25e-02
Defects in vitamin and cofactor metabolism 17 3.57e-04 1.96e-03 0.53300 0.105000 -0.523000 4.53e-01 1.90e-04
Nucleotide Excision Repair 102 4.26e-04 2.33e-03 0.23800 0.218000 0.094800 1.43e-04 9.89e-02
The role of GTSE1 in G2/M progression after G2 checkpoint 48 4.29e-04 2.34e-03 0.34200 0.107000 0.324000 1.99e-01 1.02e-04
Peroxisomal protein import 49 4.34e-04 2.36e-03 0.33900 -0.117000 -0.319000 1.59e-01 1.14e-04
Fcgamma receptor (FCGR) dependent phagocytosis 67 4.45e-04 2.40e-03 0.26400 -0.065200 0.255000 3.57e-01 3.05e-04
SUMO E3 ligases SUMOylate target proteins 131 4.47e-04 2.40e-03 0.21000 0.193000 0.083000 1.48e-04 1.02e-01
Signal regulatory protein family interactions 10 4.69e-04 2.51e-03 0.65400 -0.412000 0.507000 2.41e-02 5.48e-03
Apoptosis 135 5.16e-04 2.75e-03 0.18400 -0.047500 0.178000 3.43e-01 3.69e-04
NCAM1 interactions 21 5.17e-04 2.75e-03 0.50700 -0.487000 -0.142000 1.14e-04 2.60e-01
DNA Replication Pre-Initiation 70 5.28e-04 2.79e-03 0.28600 0.139000 0.250000 4.40e-02 3.04e-04
MAPK1/MAPK3 signaling 193 6.43e-04 3.39e-03 0.14800 -0.071700 0.130000 8.73e-02 1.96e-03
PERK regulates gene expression 28 6.61e-04 3.47e-03 0.45000 0.355000 0.277000 1.14e-03 1.14e-02
Carnitine metabolism 11 7.01e-04 3.66e-03 0.71400 -0.434000 -0.568000 1.27e-02 1.12e-03
NCAM signaling for neurite out-growth 38 7.92e-04 4.12e-03 0.36800 -0.350000 -0.112000 1.88e-04 2.31e-01
Leishmania infection 118 8.05e-04 4.16e-03 0.18700 -0.079100 0.170000 1.39e-01 1.49e-03
Homology Directed Repair 82 8.06e-04 4.16e-03 0.26100 0.186000 0.183000 3.66e-03 4.23e-03
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) 76 8.52e-04 4.38e-03 0.27000 0.195000 0.187000 3.41e-03 4.89e-03
XBP1(S) activates chaperone genes 45 8.77e-04 4.49e-03 0.31800 -0.003590 0.318000 9.67e-01 2.23e-04
RAF/MAP kinase cascade 188 8.99e-04 4.58e-03 0.14700 -0.069500 0.130000 1.02e-01 2.30e-03
Chondroitin sulfate/dermatan sulfate metabolism 38 9.29e-04 4.72e-03 0.32000 -0.242000 0.210000 1.00e-02 2.52e-02
Platelet degranulation 86 9.51e-04 4.80e-03 0.21300 -0.142000 0.158000 2.28e-02 1.13e-02
Translation 222 9.77e-04 4.91e-03 0.14400 0.144000 0.003970 2.27e-04 9.19e-01
Mitochondrial protein import 55 9.79e-04 4.91e-03 0.28800 -0.007820 -0.288000 9.20e-01 2.28e-04
Extension of Telomeres 43 1.02e-03 5.10e-03 0.35200 0.281000 0.212000 1.43e-03 1.63e-02
SCF(Skp2)-mediated degradation of p27/p21 52 1.03e-03 5.10e-03 0.31100 0.106000 0.292000 1.87e-01 2.73e-04
Interferon alpha/beta signaling 36 1.06e-03 5.26e-03 0.35000 -0.008140 0.350000 9.33e-01 2.80e-04
Metabolism of vitamins and cofactors 126 1.12e-03 5.53e-03 0.19900 -0.071400 -0.186000 1.68e-01 3.17e-04
A tetrasaccharide linker sequence is required for GAG synthesis 18 1.16e-03 5.68e-03 0.46300 -0.413000 0.210000 2.41e-03 1.24e-01
DNA Double-Strand Break Repair 109 1.16e-03 5.68e-03 0.21900 0.183000 0.120000 9.98e-04 3.04e-02
Sema4D in semaphorin signaling 23 1.17e-03 5.68e-03 0.40500 -0.246000 0.322000 4.10e-02 7.59e-03
FGFR2 alternative splicing 22 1.17e-03 5.68e-03 0.48700 0.391000 0.290000 1.51e-03 1.84e-02
Cell-Cell communication 72 1.19e-03 5.74e-03 0.22900 -0.154000 0.169000 2.37e-02 1.34e-02
Abortive elongation of HIV-1 transcript in the absence of Tat 21 1.21e-03 5.82e-03 0.49600 0.285000 0.406000 2.36e-02 1.28e-03
Attenuation phase 20 1.23e-03 5.89e-03 0.51000 0.329000 0.390000 1.09e-02 2.53e-03
Glycogen breakdown (glycogenolysis) 14 1.24e-03 5.94e-03 0.59700 -0.538000 -0.259000 4.92e-04 9.36e-02
MAPK family signaling cascades 224 1.25e-03 5.97e-03 0.13100 -0.066700 0.113000 8.70e-02 3.75e-03
TCR signaling 79 1.27e-03 6.01e-03 0.24400 0.056900 0.237000 3.83e-01 2.69e-04
Estrogen-dependent gene expression 75 1.28e-03 6.07e-03 0.26000 0.227000 0.128000 7.09e-04 5.66e-02
Nuclear Events (kinase and transcription factor activation) 54 1.29e-03 6.09e-03 0.26600 -0.119000 0.238000 1.31e-01 2.52e-03
Protein-protein interactions at synapses 41 1.40e-03 6.57e-03 0.29900 -0.198000 0.224000 2.81e-02 1.33e-02
Defective B3GAT3 causes JDSSDHD 14 1.42e-03 6.61e-03 0.52500 -0.495000 0.174000 1.35e-03 2.59e-01
Orc1 removal from chromatin 59 1.45e-03 6.75e-03 0.28700 0.115000 0.263000 1.28e-01 4.88e-04
Ion channel transport 91 1.46e-03 6.75e-03 0.23600 -0.193000 -0.135000 1.48e-03 2.60e-02
tRNA modification in the nucleus and cytosol 38 1.57e-03 7.23e-03 0.35600 0.322000 0.152000 5.97e-04 1.05e-01
Interleukin-1 signaling 84 1.57e-03 7.23e-03 0.23000 0.036700 0.227000 5.62e-01 3.26e-04
G2/M Transition 153 1.58e-03 7.23e-03 0.18200 0.144000 0.111000 2.17e-03 1.84e-02
Nuclear Envelope Breakdown 42 1.65e-03 7.53e-03 0.33800 0.303000 0.151000 6.93e-04 9.09e-02
DAG and IP3 signaling 33 1.65e-03 7.53e-03 0.37500 -0.354000 -0.125000 4.36e-04 2.15e-01
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 13 1.67e-03 7.56e-03 0.53900 -0.167000 0.513000 2.98e-01 1.37e-03
HATs acetylate histones 72 1.68e-03 7.58e-03 0.25900 0.229000 0.122000 8.12e-04 7.30e-02
Response of Mtb to phagocytosis 18 1.70e-03 7.64e-03 0.52000 0.273000 0.442000 4.50e-02 1.16e-03
Infection with Mycobacterium tuberculosis 19 1.73e-03 7.74e-03 0.50400 0.255000 0.435000 5.49e-02 1.02e-03
SARS-CoV Infections 121 1.80e-03 8.05e-03 0.18500 -0.001960 0.185000 9.70e-01 4.68e-04
mRNA Capping 26 1.84e-03 8.17e-03 0.42900 0.370000 0.218000 1.11e-03 5.41e-02
Heparan sulfate/heparin (HS-GAG) metabolism 34 1.85e-03 8.23e-03 0.32300 -0.273000 0.173000 5.94e-03 8.07e-02
Effects of PIP2 hydrolysis 19 1.91e-03 8.40e-03 0.50600 -0.324000 -0.388000 1.44e-02 3.39e-03
Transmission across Chemical Synapses 124 1.91e-03 8.40e-03 0.18400 -0.183000 -0.011400 4.33e-04 8.27e-01
Glycogen metabolism 23 1.92e-03 8.41e-03 0.44700 -0.415000 -0.167000 5.81e-04 1.65e-01
Cyclin A/B1/B2 associated events during G2/M transition 17 1.93e-03 8.43e-03 0.53500 0.395000 0.361000 4.83e-03 9.99e-03
Mitotic G2-G2/M phases 155 2.02e-03 8.82e-03 0.17700 0.137000 0.113000 3.44e-03 1.54e-02
Dual incision in TC-NER 60 2.06e-03 8.94e-03 0.27800 0.249000 0.124000 8.46e-04 9.84e-02
HCMV Infection 68 2.08e-03 9.01e-03 0.25900 0.239000 0.099800 6.59e-04 1.55e-01
Defective B4GALT7 causes EDS, progeroid type 14 2.16e-03 9.30e-03 0.51200 -0.494000 0.136000 1.39e-03 3.79e-01
B-WICH complex positively regulates rRNA expression 28 2.18e-03 9.33e-03 0.41000 0.226000 0.342000 3.83e-02 1.76e-03
Defective B3GALT6 causes EDSP2 and SEMDJL1 14 2.19e-03 9.33e-03 0.50200 -0.455000 0.212000 3.23e-03 1.70e-01
Response to elevated platelet cytosolic Ca2+ 89 2.19e-03 9.33e-03 0.19600 -0.138000 0.139000 2.42e-02 2.36e-02
Heme biosynthesis 12 2.28e-03 9.71e-03 0.59500 -0.128000 -0.581000 4.44e-01 4.96e-04
Intrinsic Pathway for Apoptosis 42 2.31e-03 9.78e-03 0.29000 -0.108000 0.269000 2.26e-01 2.53e-03
Signaling by FGFR 60 2.35e-03 9.91e-03 0.28100 0.186000 0.210000 1.29e-02 4.88e-03
ECM proteoglycans 37 2.40e-03 1.01e-02 0.30500 -0.270000 0.143000 4.56e-03 1.33e-01
Formation of the Early Elongation Complex 30 2.51e-03 1.05e-02 0.39400 0.299000 0.257000 4.65e-03 1.48e-02
Formation of the HIV-1 Early Elongation Complex 30 2.51e-03 1.05e-02 0.39400 0.299000 0.257000 4.65e-03 1.48e-02
Sealing of the nuclear envelope (NE) by ESCRT-III 20 2.52e-03 1.05e-02 0.40800 -0.279000 0.297000 3.06e-02 2.14e-02
GPVI-mediated activation cascade 18 2.68e-03 1.11e-02 0.48800 0.159000 0.461000 2.42e-01 7.09e-04
DNA strand elongation 30 2.70e-03 1.12e-02 0.38000 0.136000 0.355000 1.98e-01 7.81e-04
CaM pathway 27 2.76e-03 1.13e-02 0.38400 -0.381000 -0.044100 6.07e-04 6.92e-01
Calmodulin induced events 27 2.76e-03 1.13e-02 0.38400 -0.381000 -0.044100 6.07e-04 6.92e-01
Voltage gated Potassium channels 11 2.82e-03 1.15e-02 0.64000 -0.529000 -0.362000 2.41e-03 3.79e-02
RNA Pol II CTD phosphorylation and interaction with CE 24 3.04e-03 1.23e-02 0.42700 0.376000 0.201000 1.42e-03 8.87e-02
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 24 3.04e-03 1.23e-02 0.42700 0.376000 0.201000 1.42e-03 8.87e-02
NRAGE signals death through JNK 43 3.04e-03 1.23e-02 0.30500 -0.300000 -0.050700 6.63e-04 5.66e-01
FLT3 Signaling 199 3.18e-03 1.29e-02 0.12900 -0.068700 0.109000 9.63e-02 8.40e-03
Signaling by FGFR2 52 3.19e-03 1.29e-02 0.29400 0.200000 0.215000 1.26e-02 7.36e-03
Gap-filling DNA repair synthesis and ligation in TC-NER 59 3.26e-03 1.31e-02 0.27100 0.238000 0.129000 1.57e-03 8.61e-02
Neurexins and neuroligins 26 3.37e-03 1.35e-02 0.36100 -0.105000 0.345000 3.54e-01 2.34e-03
Switching of origins to a post-replicative state 79 3.38e-03 1.35e-02 0.23600 0.134000 0.194000 3.98e-02 2.87e-03
VEGFA-VEGFR2 Pathway 77 3.56e-03 1.41e-02 0.20300 -0.128000 0.157000 5.26e-02 1.74e-02
Visual phototransduction 38 3.57e-03 1.41e-02 0.28800 -0.223000 0.182000 1.73e-02 5.28e-02
Diseases associated with glycosaminoglycan metabolism 31 3.60e-03 1.42e-02 0.31800 -0.236000 0.213000 2.31e-02 4.00e-02
Antigen processing-Cross presentation 69 3.72e-03 1.46e-02 0.23800 0.048600 0.233000 4.86e-01 8.31e-04
Interaction between L1 and Ankyrins 15 3.87e-03 1.52e-02 0.52800 -0.467000 -0.245000 1.73e-03 1.00e-01
Integrin signaling 20 3.90e-03 1.53e-02 0.41200 -0.074700 0.405000 5.63e-01 1.71e-03
Assembly of the pre-replicative complex 56 3.94e-03 1.53e-02 0.26900 0.094900 0.252000 2.20e-01 1.13e-03
TNFR2 non-canonical NF-kB pathway 63 3.94e-03 1.53e-02 0.23500 -0.024300 0.234000 7.39e-01 1.34e-03
Metabolism of lipids 494 3.98e-03 1.54e-02 0.09550 -0.067100 -0.067900 1.16e-02 1.06e-02
Processing of Capped Intronless Pre-mRNA 25 4.37e-03 1.69e-02 0.41100 0.264000 0.315000 2.26e-02 6.36e-03
Peroxisomal lipid metabolism 22 4.38e-03 1.69e-02 0.41600 -0.095500 -0.405000 4.39e-01 1.01e-03
Activation of ATR in response to replication stress 28 4.47e-03 1.72e-02 0.38700 0.305000 0.238000 5.22e-03 2.93e-02
Protein folding 75 4.50e-03 1.72e-02 0.23000 0.084000 0.214000 2.09e-01 1.35e-03
Neurotransmitter receptors and postsynaptic signal transmission 96 4.51e-03 1.72e-02 0.19600 -0.194000 -0.023300 1.03e-03 6.94e-01
Signaling by FGFR2 IIIa TM 16 4.51e-03 1.72e-02 0.51100 0.305000 0.409000 3.46e-02 4.59e-03
Cyclin A:Cdk2-associated events at S phase entry 77 4.68e-03 1.77e-02 0.22800 0.094600 0.208000 1.52e-01 1.67e-03
Death Receptor Signalling 106 4.69e-03 1.77e-02 0.17600 -0.171000 0.039000 2.36e-03 4.90e-01
N-Glycan antennae elongation 12 4.69e-03 1.77e-02 0.50200 -0.261000 0.429000 1.18e-01 1.00e-02
Transcriptional regulation by RUNX3 86 4.71e-03 1.77e-02 0.20300 0.005620 0.203000 9.28e-01 1.19e-03
Regulation of RUNX3 expression and activity 47 4.77e-03 1.79e-02 0.28900 0.104000 0.269000 2.20e-01 1.41e-03
AUF1 (hnRNP D0) binds and destabilizes mRNA 46 4.91e-03 1.83e-02 0.29000 0.096700 0.273000 2.57e-01 1.35e-03
PIP3 activates AKT signaling 212 5.01e-03 1.86e-02 0.13600 0.044500 0.128000 2.66e-01 1.36e-03
ABC transporters in lipid homeostasis 11 5.06e-03 1.88e-02 0.57900 -0.123000 -0.566000 4.80e-01 1.16e-03
ER-Phagosome pathway 61 5.32e-03 1.97e-02 0.24700 0.063600 0.239000 3.91e-01 1.28e-03
HSP90 chaperone cycle for steroid hormone receptors (SHR) 33 5.46e-03 2.02e-02 0.35000 0.222000 0.271000 2.71e-02 7.17e-03
Positive epigenetic regulation of rRNA expression 41 5.65e-03 2.08e-02 0.30900 0.144000 0.273000 1.11e-01 2.51e-03
Inflammasomes 12 5.69e-03 2.08e-02 0.49700 -0.219000 0.446000 1.90e-01 7.47e-03
Chromatin modifying enzymes 180 5.69e-03 2.08e-02 0.14600 0.136000 0.053000 1.71e-03 2.22e-01
Chromatin organization 180 5.69e-03 2.08e-02 0.14600 0.136000 0.053000 1.71e-03 2.22e-01
Non-integrin membrane-ECM interactions 36 5.83e-03 2.12e-02 0.29200 -0.280000 0.083100 3.71e-03 3.89e-01
Formation of TC-NER Pre-Incision Complex 48 5.87e-03 2.13e-02 0.27500 0.267000 0.064000 1.39e-03 4.43e-01
Downstream TCR signaling 67 6.27e-03 2.27e-02 0.23600 0.086600 0.220000 2.21e-01 1.91e-03
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 28 6.33e-03 2.28e-02 0.36900 0.173000 0.326000 1.13e-01 2.83e-03
Hedgehog ligand biogenesis 50 6.42e-03 2.30e-02 0.27200 0.094900 0.255000 2.46e-01 1.87e-03
G2/M DNA damage checkpoint 49 6.42e-03 2.30e-02 0.28400 0.212000 0.188000 1.02e-02 2.29e-02
MET promotes cell motility 25 6.48e-03 2.32e-02 0.33500 -0.247000 0.226000 3.25e-02 5.06e-02
EPHB-mediated forward signaling 32 6.66e-03 2.37e-02 0.32200 0.019700 0.322000 8.47e-01 1.64e-03
Degradation of beta-catenin by the destruction complex 72 6.71e-03 2.38e-02 0.22900 0.108000 0.203000 1.15e-01 3.00e-03
Asparagine N-linked glycosylation 237 6.80e-03 2.41e-02 0.12700 0.055700 0.114000 1.42e-01 2.67e-03
Synthesis of IP3 and IP4 in the cytosol 19 6.94e-03 2.44e-02 0.41700 -0.416000 -0.028500 1.70e-03 8.30e-01
Activation of NF-kappaB in B cells 56 6.94e-03 2.44e-02 0.25100 0.062800 0.243000 4.17e-01 1.69e-03
Transcription-Coupled Nucleotide Excision Repair (TC-NER) 73 6.96e-03 2.44e-02 0.22500 0.206000 0.091800 2.42e-03 1.76e-01
Activation of the pre-replicative complex 27 7.05e-03 2.47e-02 0.37800 0.273000 0.261000 1.40e-02 1.88e-02
Chaperonin-mediated protein folding 69 7.09e-03 2.48e-02 0.23300 0.106000 0.207000 1.29e-01 2.98e-03
Post-translational protein phosphorylation 63 7.30e-03 2.54e-02 0.21300 -0.086400 0.194000 2.37e-01 7.68e-03
Ca-dependent events 29 7.39e-03 2.57e-02 0.33500 -0.334000 -0.020600 1.84e-03 8.48e-01
Signaling by VEGF 83 7.50e-03 2.59e-02 0.18200 -0.120000 0.136000 5.87e-02 3.23e-02
Deadenylation-dependent mRNA decay 53 7.50e-03 2.59e-02 0.25600 0.248000 0.063200 1.83e-03 4.26e-01
Amyloid fiber formation 29 7.55e-03 2.60e-02 0.30700 -0.185000 0.245000 8.54e-02 2.23e-02
Sema3A PAK dependent Axon repulsion 15 7.59e-03 2.61e-02 0.43300 -0.183000 0.392000 2.20e-01 8.60e-03
Integrin cell surface interactions 45 7.72e-03 2.64e-02 0.25100 -0.232000 0.096300 7.26e-03 2.64e-01
p130Cas linkage to MAPK signaling for integrins 10 7.83e-03 2.68e-02 0.53800 -0.141000 0.520000 4.39e-01 4.44e-03
The role of Nef in HIV-1 replication and disease pathogenesis 19 8.35e-03 2.84e-02 0.38900 -0.096200 0.377000 4.68e-01 4.46e-03
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 66 8.38e-03 2.85e-02 0.20300 -0.101000 0.176000 1.56e-01 1.34e-02
Dectin-1 mediated noncanonical NF-kB signaling 51 9.11e-03 3.09e-02 0.25900 0.083900 0.245000 3.01e-01 2.55e-03
Signaling by MET 53 9.20e-03 3.11e-02 0.24100 0.007420 0.241000 9.26e-01 2.42e-03
Platelet Aggregation (Plug Formation) 22 9.26e-03 3.11e-02 0.35300 -0.121000 0.332000 3.26e-01 7.08e-03
Prolactin receptor signaling 10 9.27e-03 3.11e-02 0.59000 -0.247000 -0.536000 1.77e-01 3.36e-03
ESR-mediated signaling 126 9.33e-03 3.13e-02 0.16800 0.148000 0.080900 4.34e-03 1.18e-01
Cyclin E associated events during G1/S transition 75 9.48e-03 3.17e-02 0.21500 0.086900 0.197000 1.94e-01 3.28e-03
HS-GAG degradation 16 9.83e-03 3.28e-02 0.43500 -0.435000 -0.013800 2.59e-03 9.24e-01
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 20 9.88e-03 3.28e-02 0.41400 -0.168000 -0.378000 1.93e-01 3.45e-03
RNA Polymerase III Transcription Initiation From Type 3 Promoter 27 1.06e-02 3.52e-02 0.34300 0.335000 0.071600 2.60e-03 5.20e-01
Platelet calcium homeostasis 18 1.08e-02 3.55e-02 0.43400 -0.389000 -0.192000 4.26e-03 1.58e-01
Hh mutants abrogate ligand secretion 47 1.13e-02 3.71e-02 0.26700 0.113000 0.242000 1.81e-01 4.15e-03
Ephrin signaling 18 1.16e-02 3.81e-02 0.37400 -0.192000 0.321000 1.58e-01 1.83e-02
Reduction of cytosolic Ca++ levels 10 1.18e-02 3.88e-02 0.56900 -0.532000 -0.202000 3.59e-03 2.69e-01
Glycerophospholipid biosynthesis 82 1.19e-02 3.90e-02 0.20600 -0.136000 -0.154000 3.37e-02 1.59e-02
Telomere C-strand (Lagging Strand) Synthesis 30 1.20e-02 3.91e-02 0.33900 0.237000 0.242000 2.46e-02 2.17e-02
G0 and Early G1 23 1.20e-02 3.91e-02 0.38700 0.285000 0.262000 1.82e-02 2.96e-02
Assembly of collagen fibrils and other multimeric structures 43 1.23e-02 4.00e-02 0.26100 -0.260000 -0.018400 3.16e-03 8.35e-01
Global Genome Nucleotide Excision Repair (GG-NER) 78 1.24e-02 4.00e-02 0.20100 0.193000 0.055000 3.25e-03 4.02e-01
TP53 Regulates Transcription of Cell Cycle Genes 43 1.24e-02 4.02e-02 0.26800 0.063300 0.261000 4.73e-01 3.15e-03
Ubiquitin-dependent degradation of Cyclin D 44 1.25e-02 4.03e-02 0.26900 0.086900 0.254000 3.19e-01 3.56e-03
G1/S DNA Damage Checkpoints 57 1.26e-02 4.03e-02 0.24000 0.105000 0.216000 1.72e-01 4.85e-03
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 10 1.26e-02 4.04e-02 0.55100 0.109000 0.540000 5.49e-01 3.13e-03
Elastic fibre formation 34 1.26e-02 4.04e-02 0.28200 -0.040700 0.279000 6.81e-01 4.83e-03
Biotin transport and metabolism 10 1.27e-02 4.04e-02 0.53600 -0.020100 -0.535000 9.12e-01 3.39e-03
PCP/CE pathway 79 1.28e-02 4.05e-02 0.18800 -0.013200 0.187000 8.39e-01 4.09e-03
ATF4 activates genes in response to endoplasmic reticulum stress 24 1.28e-02 4.05e-02 0.37500 0.296000 0.230000 1.20e-02 5.11e-02
BBSome-mediated cargo-targeting to cilium 18 1.30e-02 4.12e-02 0.40400 0.401000 0.049700 3.25e-03 7.15e-01
G alpha (12/13) signalling events 54 1.31e-02 4.12e-02 0.23400 -0.232000 -0.029900 3.25e-03 7.05e-01
PKA activation 15 1.32e-02 4.15e-02 0.44800 -0.439000 -0.090000 3.28e-03 5.47e-01
p75NTR signals via NF-kB 13 1.33e-02 4.16e-02 0.46500 0.001700 0.465000 9.92e-01 3.72e-03
G-protein mediated events 40 1.35e-02 4.22e-02 0.27200 -0.268000 -0.042000 3.35e-03 6.46e-01
Role of LAT2/NTAL/LAB on calcium mobilization 11 1.35e-02 4.22e-02 0.53600 0.200000 0.497000 2.50e-01 4.33e-03
Degradation of AXIN 47 1.39e-02 4.34e-02 0.25900 0.101000 0.239000 2.31e-01 4.66e-03
Synthesis of bile acids and bile salts 18 1.43e-02 4.45e-02 0.40800 -0.099000 -0.395000 4.67e-01 3.69e-03
trans-Golgi Network Vesicle Budding 63 1.44e-02 4.47e-02 0.22900 0.157000 0.167000 3.10e-02 2.21e-02
Sema4D induced cell migration and growth-cone collapse 19 1.48e-02 4.57e-02 0.35200 -0.206000 0.286000 1.20e-01 3.11e-02
GRB2:SOS provides linkage to MAPK signaling for Integrins 10 1.48e-02 4.57e-02 0.49300 -0.202000 0.449000 2.69e-01 1.39e-02
Regulation of activated PAK-2p34 by proteasome mediated degradation 42 1.49e-02 4.59e-02 0.26900 0.084600 0.255000 3.43e-01 4.23e-03
Activation of PPARGC1A (PGC-1alpha) by phosphorylation 10 1.53e-02 4.70e-02 0.57000 -0.379000 -0.426000 3.79e-02 1.98e-02
Negative regulation of NOTCH4 signaling 47 1.54e-02 4.71e-02 0.24700 0.039400 0.244000 6.41e-01 3.86e-03
CRMPs in Sema3A signaling 13 1.55e-02 4.72e-02 0.42300 -0.253000 0.339000 1.14e-01 3.41e-02
Diseases of glycosylation 97 1.58e-02 4.81e-02 0.15500 -0.110000 0.109000 6.25e-02 6.37e-02
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 25 1.59e-02 4.83e-02 0.35700 0.294000 0.203000 1.10e-02 7.93e-02
NIK-->noncanonical NF-kB signaling 50 1.59e-02 4.83e-02 0.24500 0.077700 0.232000 3.42e-01 4.56e-03
Translation of structural proteins 25 1.60e-02 4.85e-02 0.30400 -0.194000 0.234000 9.41e-02 4.30e-02
Opioid Signalling 64 1.63e-02 4.91e-02 0.21900 -0.200000 -0.087700 5.66e-03 2.26e-01
Integration of energy metabolism 72 1.63e-02 4.91e-02 0.20200 -0.194000 -0.056500 4.42e-03 4.08e-01
MET activates PTK2 signaling 15 1.65e-02 4.96e-02 0.41900 -0.419000 0.014700 5.02e-03 9.22e-01
RNA Polymerase I Promoter Escape 25 1.67e-02 5.01e-02 0.35500 0.292000 0.202000 1.15e-02 8.10e-02
Golgi Associated Vesicle Biogenesis 49 1.69e-02 5.05e-02 0.25300 0.210000 0.142000 1.13e-02 8.50e-02
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 26 1.70e-02 5.07e-02 0.32600 0.044500 0.323000 6.95e-01 4.34e-03
DDX58/IFIH1-mediated induction of interferon-alpha/beta 52 1.72e-02 5.12e-02 0.21700 -0.054400 0.210000 4.98e-01 8.89e-03
The NLRP3 inflammasome 10 1.75e-02 5.15e-02 0.49800 -0.089300 0.490000 6.25e-01 7.33e-03
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 43 1.75e-02 5.15e-02 0.26300 0.101000 0.243000 2.52e-01 5.80e-03
p53-Independent DNA Damage Response 43 1.75e-02 5.15e-02 0.26300 0.101000 0.243000 2.52e-01 5.80e-03
p53-Independent G1/S DNA damage checkpoint 43 1.75e-02 5.15e-02 0.26300 0.101000 0.243000 2.52e-01 5.80e-03
HS-GAG biosynthesis 18 1.77e-02 5.20e-02 0.35500 -0.292000 0.201000 3.18e-02 1.40e-01
Meiosis 38 1.79e-02 5.22e-02 0.26100 0.261000 -0.009640 5.47e-03 9.18e-01
p53-Dependent G1 DNA Damage Response 56 1.79e-02 5.22e-02 0.23100 0.091700 0.212000 2.36e-01 6.17e-03
p53-Dependent G1/S DNA damage checkpoint 56 1.79e-02 5.22e-02 0.23100 0.091700 0.212000 2.36e-01 6.17e-03
Regulation of MECP2 expression and activity 26 1.82e-02 5.29e-02 0.32900 -0.078400 -0.320000 4.89e-01 4.77e-03
Degradation of cysteine and homocysteine 12 1.84e-02 5.33e-02 0.50700 -0.303000 -0.407000 6.93e-02 1.47e-02
Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 46 1.85e-02 5.34e-02 0.25400 0.104000 0.232000 2.24e-01 6.59e-03
Detoxification of Reactive Oxygen Species 26 1.85e-02 5.34e-02 0.30300 -0.291000 0.084000 1.04e-02 4.59e-01
Interleukin-12 family signaling 36 1.88e-02 5.41e-02 0.26800 0.000371 0.268000 9.97e-01 5.42e-03
PLC beta mediated events 39 1.93e-02 5.54e-02 0.26400 -0.260000 -0.043900 4.95e-03 6.36e-01
Intra-Golgi and retrograde Golgi-to-ER traffic 148 1.95e-02 5.58e-02 0.14100 0.129000 0.057200 6.87e-03 2.32e-01
Negative regulation of NMDA receptor-mediated neuronal transmission 12 1.98e-02 5.68e-02 0.47400 -0.467000 -0.079700 5.11e-03 6.33e-01
Cytosolic sensors of pathogen-associated DNA 52 2.01e-02 5.73e-02 0.24200 0.190000 0.149000 1.77e-02 6.36e-02
Toll-like Receptor Cascades 115 2.01e-02 5.73e-02 0.14400 -0.029600 0.141000 5.84e-01 9.04e-03
Cobalamin (Cbl, vitamin B12) transport and metabolism 11 2.07e-02 5.90e-02 0.45500 0.149000 -0.430000 3.92e-01 1.36e-02
Retrograde transport at the Trans-Golgi-Network 43 2.09e-02 5.90e-02 0.22600 0.191000 -0.120000 3.05e-02 1.73e-01
RNA Polymerase III Transcription Initiation 34 2.09e-02 5.90e-02 0.28600 0.272000 0.089600 6.07e-03 3.66e-01
CLEC7A (Dectin-1) signaling 80 2.10e-02 5.90e-02 0.17500 -0.018200 0.174000 7.78e-01 7.36e-03
Potential therapeutics for SARS 66 2.10e-02 5.90e-02 0.19100 -0.026600 0.189000 7.09e-01 7.96e-03
Long-term potentiation 10 2.10e-02 5.90e-02 0.51600 -0.508000 -0.093500 5.46e-03 6.09e-01
Interferon gamma signaling 44 2.11e-02 5.90e-02 0.22900 -0.059700 0.222000 4.94e-01 1.11e-02
Cilium Assembly 158 2.18e-02 6.09e-02 0.12000 0.114000 -0.038700 1.39e-02 4.03e-01
Defective CFTR causes cystic fibrosis 50 2.19e-02 6.09e-02 0.23900 0.099400 0.217000 2.25e-01 7.99e-03
Sphingolipid metabolism 64 2.19e-02 6.09e-02 0.19200 -0.036000 0.188000 6.19e-01 9.36e-03
MET activates RAP1 and RAC1 10 2.20e-02 6.10e-02 0.50500 0.045700 0.503000 8.03e-01 5.87e-03
Association of TriC/CCT with target proteins during biosynthesis 36 2.21e-02 6.10e-02 0.28800 0.210000 0.196000 2.91e-02 4.19e-02
ATF6 (ATF6-alpha) activates chaperone genes 10 2.21e-02 6.10e-02 0.51700 0.117000 0.503000 5.21e-01 5.85e-03
Signaling by PDGF 46 2.21e-02 6.10e-02 0.21600 -0.181000 0.118000 3.36e-02 1.67e-01
Sphingolipid de novo biosynthesis 32 2.25e-02 6.20e-02 0.28400 0.036100 0.281000 7.24e-01 5.92e-03
UCH proteinases 74 2.27e-02 6.21e-02 0.19400 0.071700 0.180000 2.87e-01 7.37e-03
N-glycan antennae elongation in the medial/trans-Golgi 17 2.28e-02 6.21e-02 0.36100 -0.124000 0.339000 3.76e-01 1.56e-02
Leading Strand Synthesis 14 2.28e-02 6.21e-02 0.45300 0.227000 0.392000 1.41e-01 1.12e-02
Polymerase switching 14 2.28e-02 6.21e-02 0.45300 0.227000 0.392000 1.41e-01 1.12e-02
Retinoid metabolism and transport 19 2.31e-02 6.29e-02 0.33300 -0.263000 0.205000 4.76e-02 1.23e-01
RHO GTPases activate PAKs 19 2.33e-02 6.34e-02 0.33500 -0.293000 0.163000 2.72e-02 2.18e-01
CDK-mediated phosphorylation and removal of Cdc6 63 2.37e-02 6.43e-02 0.21400 0.125000 0.174000 8.68e-02 1.69e-02
Recognition of DNA damage by PCNA-containing replication complex 28 2.39e-02 6.45e-02 0.32200 0.252000 0.200000 2.12e-02 6.66e-02
FGFR2 mutant receptor activation 18 2.41e-02 6.50e-02 0.39200 0.165000 0.356000 2.25e-01 8.95e-03
Intracellular signaling by second messengers 244 2.41e-02 6.50e-02 0.09860 -0.012000 0.097900 7.48e-01 8.83e-03
Class A/1 (Rhodopsin-like receptors) 39 2.42e-02 6.51e-02 0.23600 -0.088900 0.218000 3.37e-01 1.84e-02
Toll Like Receptor 4 (TLR4) Cascade 102 2.49e-02 6.67e-02 0.14700 -0.046700 0.139000 4.17e-01 1.55e-02
Diseases associated with the TLR signaling cascade 16 2.50e-02 6.67e-02 0.36200 -0.174000 0.317000 2.28e-01 2.80e-02
Diseases of Immune System 16 2.50e-02 6.67e-02 0.36200 -0.174000 0.317000 2.28e-01 2.80e-02
Biological oxidations 85 2.50e-02 6.67e-02 0.18400 -0.141000 -0.118000 2.49e-02 5.95e-02
Diseases of metabolism 154 2.51e-02 6.68e-02 0.12700 -0.126000 -0.007630 6.97e-03 8.71e-01
Pre-NOTCH Processing in Golgi 14 2.52e-02 6.68e-02 0.40300 -0.398000 0.062000 9.92e-03 6.88e-01
Mitochondrial calcium ion transport 21 2.57e-02 6.80e-02 0.33800 -0.011200 -0.338000 9.29e-01 7.33e-03
APC/C-mediated degradation of cell cycle proteins 72 2.68e-02 7.04e-02 0.19800 0.135000 0.146000 4.85e-02 3.28e-02
Regulation of mitotic cell cycle 72 2.68e-02 7.04e-02 0.19800 0.135000 0.146000 4.85e-02 3.28e-02
Protein ubiquitination 56 2.68e-02 7.04e-02 0.22300 0.185000 0.124000 1.65e-02 1.08e-01
Formation of the cornified envelope 10 2.70e-02 7.07e-02 0.45900 -0.427000 0.168000 1.95e-02 3.58e-01
Rho GTPase cycle 104 2.70e-02 7.07e-02 0.14000 -0.107000 0.089900 6.03e-02 1.14e-01
Deadenylation of mRNA 24 2.71e-02 7.09e-02 0.32000 0.317000 0.047400 7.24e-03 6.88e-01
Membrane Trafficking 486 2.73e-02 7.12e-02 0.07530 0.070200 0.027400 8.87e-03 3.07e-01
Collagen chain trimerization 32 2.78e-02 7.23e-02 0.27600 -0.274000 -0.038500 7.45e-03 7.07e-01
PTEN Regulation 128 2.83e-02 7.34e-02 0.14700 0.082200 0.122000 1.09e-01 1.76e-02
Cell-extracellular matrix interactions 16 2.86e-02 7.40e-02 0.35200 -0.258000 0.238000 7.37e-02 9.88e-02
Unwinding of DNA 10 2.86e-02 7.40e-02 0.47400 -0.035100 0.473000 8.47e-01 9.62e-03
Regulation of RAS by GAPs 57 2.88e-02 7.40e-02 0.21500 0.088800 0.196000 2.47e-01 1.05e-02
Nonhomologous End-Joining (NHEJ) 30 2.88e-02 7.40e-02 0.27300 0.271000 -0.028000 1.02e-02 7.91e-01
Syndecan interactions 17 2.88e-02 7.40e-02 0.36000 -0.048400 0.357000 7.30e-01 1.09e-02
Deubiquitination 212 2.89e-02 7.41e-02 0.11500 0.084500 0.078300 3.49e-02 5.07e-02
Defects in cobalamin (B12) metabolism 10 2.91e-02 7.42e-02 0.45700 0.138000 -0.436000 4.49e-01 1.70e-02
Synthesis of substrates in N-glycan biosythesis 52 2.91e-02 7.42e-02 0.19600 -0.107000 0.164000 1.82e-01 4.09e-02
PKA-mediated phosphorylation of CREB 17 2.92e-02 7.42e-02 0.37900 -0.372000 -0.072200 7.86e-03 6.06e-01
Diseases of carbohydrate metabolism 26 2.92e-02 7.42e-02 0.30600 -0.301000 -0.055100 7.85e-03 6.27e-01
Cell junction organization 46 2.93e-02 7.42e-02 0.21300 -0.203000 0.064800 1.71e-02 4.47e-01
Transcriptional regulation by RUNX1 139 2.95e-02 7.46e-02 0.14100 0.082000 0.114000 9.63e-02 2.04e-02
Polymerase switching on the C-strand of the telomere 22 2.96e-02 7.47e-02 0.35300 0.252000 0.248000 4.11e-02 4.42e-02
DNA Damage/Telomere Stress Induced Senescence 26 2.97e-02 7.48e-02 0.32500 0.225000 0.234000 4.72e-02 3.88e-02
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA 15 2.99e-02 7.51e-02 0.42100 0.368000 0.204000 1.37e-02 1.71e-01
Lagging Strand Synthesis 20 2.99e-02 7.51e-02 0.36800 0.221000 0.295000 8.72e-02 2.26e-02
GPCR ligand binding 74 3.00e-02 7.52e-02 0.17100 -0.169000 0.029100 1.23e-02 6.66e-01
Mitotic Telophase/Cytokinesis 10 3.02e-02 7.53e-02 0.44700 0.398000 -0.204000 2.93e-02 2.64e-01
Signaling by Non-Receptor Tyrosine Kinases 42 3.02e-02 7.53e-02 0.22500 -0.050700 0.219000 5.70e-01 1.42e-02
Signaling by PTK6 42 3.02e-02 7.53e-02 0.22500 -0.050700 0.219000 5.70e-01 1.42e-02
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 40 3.04e-02 7.55e-02 0.26100 0.169000 0.199000 6.43e-02 2.99e-02
Transcriptional Regulation by MECP2 42 3.05e-02 7.56e-02 0.25400 -0.152000 -0.203000 8.90e-02 2.27e-02
Caspase activation via extrinsic apoptotic signalling pathway 20 3.13e-02 7.74e-02 0.31200 -0.255000 0.179000 4.83e-02 1.66e-01
APC/C:Cdc20 mediated degradation of mitotic proteins 63 3.15e-02 7.76e-02 0.20700 0.134000 0.158000 6.60e-02 3.07e-02
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 63 3.15e-02 7.76e-02 0.20700 0.134000 0.158000 6.60e-02 3.07e-02
Phase I - Functionalization of compounds 39 3.16e-02 7.77e-02 0.25900 -0.226000 -0.126000 1.45e-02 1.73e-01
Laminin interactions 20 3.17e-02 7.78e-02 0.34700 -0.339000 -0.071600 8.67e-03 5.80e-01
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 62 3.20e-02 7.81e-02 0.20700 0.121000 0.169000 1.01e-01 2.18e-02
Cdc20:Phospho-APC/C mediated degradation of Cyclin A 62 3.20e-02 7.81e-02 0.20700 0.121000 0.169000 1.01e-01 2.18e-02
Cell death signalling via NRAGE, NRIF and NADE 57 3.20e-02 7.81e-02 0.19900 -0.199000 -0.005390 9.38e-03 9.44e-01
Cholesterol biosynthesis 23 3.23e-02 7.85e-02 0.29500 -0.275000 0.107000 2.24e-02 3.76e-01
Keratinization 12 3.23e-02 7.85e-02 0.40200 -0.345000 0.207000 3.86e-02 2.15e-01
Class B/2 (Secretin family receptors) 33 3.25e-02 7.89e-02 0.28200 -0.236000 -0.155000 1.91e-02 1.23e-01
Processing of Intronless Pre-mRNAs 17 3.26e-02 7.90e-02 0.39300 0.223000 0.324000 1.12e-01 2.06e-02
Signaling by NOTCH4 70 3.28e-02 7.93e-02 0.18300 0.025100 0.181000 7.17e-01 8.96e-03
Formation of Senescence-Associated Heterochromatin Foci (SAHF) 10 3.33e-02 8.04e-02 0.48900 0.114000 0.475000 5.31e-01 9.29e-03
Downstream signaling events of B Cell Receptor (BCR) 67 3.34e-02 8.04e-02 0.18000 -0.009050 0.180000 8.98e-01 1.09e-02
Adaptive Immune System 477 3.40e-02 8.18e-02 0.07330 0.024200 0.069200 3.72e-01 1.06e-02
Caspase activation via Death Receptors in the presence of ligand 11 3.42e-02 8.21e-02 0.41500 -0.239000 0.339000 1.70e-01 5.18e-02
Basigin interactions 17 3.45e-02 8.24e-02 0.34000 -0.317000 0.123000 2.37e-02 3.81e-01
Signaling by TGF-beta Receptor Complex 66 3.45e-02 8.24e-02 0.19900 0.119000 0.160000 9.64e-02 2.50e-02
Transcriptional regulation of granulopoiesis 23 3.45e-02 8.24e-02 0.30700 -0.007540 0.307000 9.50e-01 1.09e-02
Negative regulation of MET activity 16 3.48e-02 8.29e-02 0.39700 0.182000 0.353000 2.09e-01 1.45e-02
RORA activates gene expression 17 3.50e-02 8.31e-02 0.37500 -0.106000 -0.360000 4.50e-01 1.02e-02
Antigen Presentation: Folding, assembly and peptide loading of class I MHC 17 3.53e-02 8.38e-02 0.39000 0.229000 0.315000 1.03e-01 2.44e-02
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol 10 3.56e-02 8.42e-02 0.48800 -0.141000 -0.468000 4.41e-01 1.05e-02
Interleukin-12 signaling 31 3.57e-02 8.43e-02 0.26400 -0.000325 0.264000 9.98e-01 1.09e-02
Senescence-Associated Secretory Phenotype (SASP) 45 3.58e-02 8.45e-02 0.22700 0.046200 0.222000 5.92e-01 9.93e-03
Diseases of signal transduction by growth factor receptors and second messengers 304 3.61e-02 8.49e-02 0.08130 -0.026400 0.076900 4.33e-01 2.21e-02
TNFR1-induced proapoptotic signaling 11 3.62e-02 8.50e-02 0.41000 -0.322000 0.254000 6.44e-02 1.45e-01
p75 NTR receptor-mediated signalling 73 3.63e-02 8.51e-02 0.16400 -0.155000 0.053600 2.24e-02 4.29e-01
Resolution of AP sites via the multiple-nucleotide patch replacement pathway 24 3.64e-02 8.51e-02 0.32700 0.206000 0.254000 8.08e-02 3.10e-02
Sialic acid metabolism 23 3.64e-02 8.51e-02 0.30200 -0.302000 0.021000 1.23e-02 8.62e-01
Metabolism of steroid hormones 12 3.67e-02 8.55e-02 0.40400 -0.117000 0.387000 4.84e-01 2.02e-02
PKA activation in glucagon signalling 14 3.68e-02 8.57e-02 0.40300 -0.397000 -0.070800 1.02e-02 6.47e-01
Triglyceride catabolism 13 3.73e-02 8.65e-02 0.44300 -0.275000 -0.347000 8.66e-02 3.01e-02
RUNX1 regulates transcription of genes involved in differentiation of HSCs 55 3.75e-02 8.69e-02 0.21200 0.094600 0.190000 2.26e-01 1.52e-02
Transcriptional Regulation by E2F6 29 3.87e-02 8.95e-02 0.28600 0.268000 0.101000 1.26e-02 3.47e-01
Metabolism of fat-soluble vitamins 22 3.88e-02 8.97e-02 0.28800 -0.235000 0.166000 5.64e-02 1.78e-01
Ub-specific processing proteases 145 3.92e-02 9.04e-02 0.13300 0.098800 0.088500 4.06e-02 6.69e-02
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 15 3.95e-02 9.10e-02 0.35500 -0.125000 0.332000 4.03e-01 2.60e-02
PCNA-Dependent Long Patch Base Excision Repair 21 3.97e-02 9.11e-02 0.34300 0.189000 0.287000 1.34e-01 2.31e-02
COPI-dependent Golgi-to-ER retrograde traffic 62 3.99e-02 9.15e-02 0.20200 0.137000 0.148000 6.32e-02 4.39e-02
SUMOylation of transcription factors 14 4.03e-02 9.23e-02 0.40700 0.134000 0.385000 3.86e-01 1.27e-02
Amino acid transport across the plasma membrane 20 4.07e-02 9.28e-02 0.31100 -0.303000 0.071400 1.91e-02 5.81e-01
HCMV Late Events 43 4.08e-02 9.31e-02 0.23200 0.220000 0.070600 1.24e-02 4.24e-01
RHO GTPases Activate ROCKs 18 4.12e-02 9.36e-02 0.31500 -0.194000 0.248000 1.54e-01 6.91e-02
RHO GTPases activate CIT 17 4.20e-02 9.52e-02 0.32600 -0.151000 0.289000 2.80e-01 3.92e-02
Inwardly rectifying K+ channels 17 4.20e-02 9.52e-02 0.37800 -0.212000 -0.314000 1.31e-01 2.51e-02
Signalling to RAS 16 4.23e-02 9.57e-02 0.34300 -0.328000 0.100000 2.34e-02 4.88e-01
Chondroitin sulfate biosynthesis 14 4.32e-02 9.75e-02 0.35900 -0.155000 0.324000 3.14e-01 3.62e-02
Class I peroxisomal membrane protein import 20 4.36e-02 9.82e-02 0.31200 0.040200 -0.310000 7.56e-01 1.65e-02
Bile acid and bile salt metabolism 20 4.37e-02 9.82e-02 0.33800 -0.116000 -0.317000 3.69e-01 1.42e-02
Signaling by Retinoic Acid 29 4.37e-02 9.82e-02 0.28900 -0.177000 -0.229000 1.00e-01 3.28e-02
Calnexin/calreticulin cycle 23 4.42e-02 9.91e-02 0.31600 0.124000 0.291000 3.02e-01 1.57e-02
Regulation of APC/C activators between G1/S and early anaphase 67 4.46e-02 9.98e-02 0.18900 0.108000 0.155000 1.26e-01 2.80e-02
Metabolism of polyamines 50 4.48e-02 9.99e-02 0.21500 0.089700 0.196000 2.73e-01 1.69e-02
Nucleotide salvage 18 4.48e-02 9.99e-02 0.32000 -0.307000 0.090700 2.40e-02 5.05e-01
Autodegradation of the E3 ubiquitin ligase COP1 44 4.49e-02 1.00e-01 0.22900 0.094800 0.209000 2.77e-01 1.68e-02
Clathrin-mediated endocytosis 109 4.55e-02 1.01e-01 0.14900 0.098700 0.112000 7.59e-02 4.42e-02
Vesicle-mediated transport 508 4.57e-02 1.01e-01 0.06940 0.060600 0.033700 2.09e-02 1.99e-01
FCERI mediated NF-kB activation 65 4.63e-02 1.03e-01 0.18300 0.045300 0.177000 5.29e-01 1.36e-02
Reproduction 44 4.65e-02 1.03e-01 0.21200 0.212000 -0.004140 1.49e-02 9.62e-01
Assembly Of The HIV Virion 12 4.65e-02 1.03e-01 0.38500 -0.147000 0.356000 3.79e-01 3.27e-02
FCGR3A-mediated IL10 synthesis 25 4.70e-02 1.03e-01 0.29400 -0.284000 -0.075900 1.39e-02 5.11e-01
Cross-presentation of soluble exogenous antigens (endosomes) 40 4.71e-02 1.03e-01 0.23200 0.058000 0.225000 5.26e-01 1.38e-02
Myogenesis 26 4.77e-02 1.05e-01 0.28700 -0.279000 -0.066500 1.39e-02 5.57e-01
RHO GTPases activate PKNs 29 4.80e-02 1.05e-01 0.25400 -0.042400 0.250000 6.93e-01 1.97e-02
Disorders of transmembrane transporters 107 4.80e-02 1.05e-01 0.14700 0.067800 0.130000 2.27e-01 2.04e-02
Ion transport by P-type ATPases 34 4.81e-02 1.05e-01 0.25400 -0.241000 -0.079400 1.51e-02 4.23e-01
MyD88-independent TLR4 cascade 83 4.81e-02 1.05e-01 0.14500 -0.070600 0.126000 2.67e-01 4.74e-02
TRIF(TICAM1)-mediated TLR4 signaling 83 4.81e-02 1.05e-01 0.14500 -0.070600 0.126000 2.67e-01 4.74e-02
Translesion Synthesis by POLH 16 4.84e-02 1.05e-01 0.37200 0.347000 0.136000 1.64e-02 3.45e-01
E3 ubiquitin ligases ubiquitinate target proteins 39 4.84e-02 1.05e-01 0.24500 0.198000 0.145000 3.26e-02 1.18e-01
C-type lectin receptors (CLRs) 94 4.85e-02 1.05e-01 0.14200 -0.016700 0.141000 7.81e-01 1.81e-02
Signaling by BRAF and RAF fusions 52 4.89e-02 1.06e-01 0.18500 -0.173000 0.063400 3.07e-02 4.29e-01
Telomere Extension By Telomerase 19 4.91e-02 1.06e-01 0.33300 0.325000 0.075600 1.43e-02 5.68e-01
Vif-mediated degradation of APOBEC3G 43 4.94e-02 1.06e-01 0.22700 0.085500 0.210000 3.33e-01 1.71e-02
Interleukin-37 signaling 16 4.96e-02 1.07e-01 0.35400 0.027200 0.353000 8.51e-01 1.47e-02
Regulation of ornithine decarboxylase (ODC) 44 4.97e-02 1.07e-01 0.22200 0.067700 0.211000 4.37e-01 1.55e-02
Triglyceride metabolism 20 4.98e-02 1.07e-01 0.33700 -0.163000 -0.295000 2.07e-01 2.25e-02
Inhibition of DNA recombination at telomere 19 5.04e-02 1.08e-01 0.34700 0.290000 0.192000 2.89e-02 1.48e-01
RNA Polymerase I Transcription Termination 25 5.04e-02 1.08e-01 0.30400 0.248000 0.176000 3.22e-02 1.29e-01
Defective EXT1 causes exostoses 1, TRPS2 and CHDS 11 5.11e-02 1.08e-01 0.39500 -0.360000 0.162000 3.86e-02 3.54e-01
Defective EXT2 causes exostoses 2 11 5.11e-02 1.08e-01 0.39500 -0.360000 0.162000 3.86e-02 3.54e-01
SUMOylation of transcription cofactors 38 5.11e-02 1.08e-01 0.22900 0.228000 0.022800 1.50e-02 8.08e-01
SARS-CoV-2 Infection 56 5.11e-02 1.08e-01 0.18800 0.013900 0.188000 8.57e-01 1.52e-02
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 19 5.14e-02 1.09e-01 0.34600 0.191000 0.289000 1.50e-01 2.94e-02
CDT1 association with the CDC6:ORC:origin complex 48 5.17e-02 1.09e-01 0.21800 0.120000 0.182000 1.52e-01 2.93e-02
Signaling by the B Cell Receptor (BCR) 85 5.18e-02 1.09e-01 0.15100 0.000958 0.151000 9.88e-01 1.63e-02
GABA receptor activation 27 5.19e-02 1.09e-01 0.29200 -0.222000 -0.189000 4.57e-02 8.88e-02
Presynaptic phase of homologous DNA pairing and strand exchange 29 5.22e-02 1.09e-01 0.26600 0.261000 0.051000 1.51e-02 6.35e-01
Regulation of TP53 Activity through Methylation 14 5.22e-02 1.09e-01 0.35700 0.349000 -0.078500 2.39e-02 6.11e-01
RNA Polymerase III Transcription Initiation From Type 2 Promoter 25 5.22e-02 1.09e-01 0.29600 0.270000 0.123000 1.96e-02 2.89e-01
RAF-independent MAPK1/3 activation 21 5.24e-02 1.10e-01 0.28100 -0.157000 0.233000 2.13e-01 6.47e-02
Unblocking of NMDA receptors, glutamate binding and activation 10 5.29e-02 1.10e-01 0.45700 -0.440000 -0.124000 1.60e-02 4.99e-01
Stabilization of p53 48 5.33e-02 1.11e-01 0.21700 0.121000 0.180000 1.48e-01 3.11e-02
HSF1-dependent transactivation 30 5.35e-02 1.11e-01 0.25800 0.035400 0.255000 7.37e-01 1.56e-02
AKT phosphorylates targets in the nucleus 10 5.45e-02 1.13e-01 0.47400 -0.381000 -0.282000 3.70e-02 1.23e-01
HDR through Homologous Recombination (HRR) 49 5.47e-02 1.13e-01 0.21500 0.170000 0.131000 3.95e-02 1.14e-01
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 63 5.48e-02 1.13e-01 0.18900 0.117000 0.149000 1.08e-01 4.14e-02
Homologous DNA Pairing and Strand Exchange 30 5.52e-02 1.14e-01 0.26100 0.253000 0.060700 1.64e-02 5.65e-01
Signaling by high-kinase activity BRAF mutants 27 5.53e-02 1.14e-01 0.25000 -0.088200 0.234000 4.28e-01 3.51e-02
Transcriptional regulation by RUNX2 99 5.53e-02 1.14e-01 0.13800 -0.002400 0.138000 9.67e-01 1.80e-02
SCF-beta-TrCP mediated degradation of Emi1 45 5.55e-02 1.14e-01 0.21500 0.061700 0.206000 4.75e-01 1.72e-02
Regulation of KIT signaling 14 5.70e-02 1.17e-01 0.33700 -0.224000 0.252000 1.46e-01 1.03e-01
Activation of gene expression by SREBF (SREBP) 40 5.70e-02 1.17e-01 0.22800 -0.215000 -0.076600 1.87e-02 4.02e-01
Translocation of SLC2A4 (GLUT4) to the plasma membrane 50 5.70e-02 1.17e-01 0.20800 -0.096300 -0.184000 2.39e-01 2.43e-02
Vpu mediated degradation of CD4 43 5.75e-02 1.17e-01 0.22100 0.081000 0.205000 3.59e-01 1.99e-02
L1CAM interactions 70 5.85e-02 1.19e-01 0.15400 -0.145000 0.054100 3.68e-02 4.34e-01
COPII-mediated vesicle transport 56 5.86e-02 1.19e-01 0.19200 0.181000 0.066300 1.96e-02 3.91e-01
Listeria monocytogenes entry into host cells 15 5.94e-02 1.21e-01 0.37500 0.162000 0.338000 2.78e-01 2.35e-02
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion 14 5.95e-02 1.21e-01 0.33500 -0.216000 0.257000 1.63e-01 9.66e-02
PRC2 methylates histones and DNA 14 5.98e-02 1.21e-01 0.39500 0.258000 0.299000 9.44e-02 5.24e-02
Response of EIF2AK1 (HRI) to heme deficiency 14 6.02e-02 1.21e-01 0.37200 0.068200 0.366000 6.59e-01 1.78e-02
NF-kB is activated and signals survival 10 6.02e-02 1.21e-01 0.40500 -0.142000 0.380000 4.38e-01 3.76e-02
HSF1 activation 22 6.08e-02 1.22e-01 0.31300 0.179000 0.257000 1.47e-01 3.69e-02
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs 10 6.16e-02 1.24e-01 0.46600 0.337000 0.321000 6.49e-02 7.84e-02
O-linked glycosylation 51 6.16e-02 1.24e-01 0.17800 -0.163000 0.072300 4.49e-02 3.72e-01
EPH-ephrin mediated repulsion of cells 37 6.21e-02 1.25e-01 0.20500 -0.125000 0.162000 1.88e-01 8.77e-02
SUMOylation of intracellular receptors 23 6.26e-02 1.25e-01 0.30500 -0.247000 -0.178000 4.02e-02 1.39e-01
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane 18 6.31e-02 1.26e-01 0.31500 -0.006640 0.314000 9.61e-01 2.09e-02
RNA Polymerase I Transcription 44 6.40e-02 1.27e-01 0.22100 0.144000 0.167000 9.77e-02 5.57e-02
Aquaporin-mediated transport 29 6.41e-02 1.27e-01 0.27100 -0.216000 -0.164000 4.46e-02 1.27e-01
RNA Polymerase I Promoter Clearance 43 6.41e-02 1.27e-01 0.22300 0.161000 0.155000 6.78e-02 7.95e-02
Negative regulation of the PI3K/AKT network 69 6.44e-02 1.27e-01 0.16400 0.014800 0.163000 8.32e-01 1.95e-02
Activation of NMDA receptors and postsynaptic events 52 6.44e-02 1.27e-01 0.18200 -0.180000 0.022700 2.48e-02 7.78e-01
Paradoxical activation of RAF signaling by kinase inactive BRAF 36 6.47e-02 1.27e-01 0.20700 -0.167000 0.122000 8.40e-02 2.05e-01
Signaling by RAS mutants 36 6.47e-02 1.27e-01 0.20700 -0.167000 0.122000 8.40e-02 2.05e-01
Signaling by moderate kinase activity BRAF mutants 36 6.47e-02 1.27e-01 0.20700 -0.167000 0.122000 8.40e-02 2.05e-01
Signaling downstream of RAS mutants 36 6.47e-02 1.27e-01 0.20700 -0.167000 0.122000 8.40e-02 2.05e-01
RIP-mediated NFkB activation via ZBP1 14 6.49e-02 1.28e-01 0.36900 0.076300 0.361000 6.21e-01 1.95e-02
Glycogen storage diseases 11 6.51e-02 1.28e-01 0.41200 -0.407000 -0.060900 1.94e-02 7.27e-01
Regulation of Apoptosis 45 6.69e-02 1.31e-01 0.21000 0.078200 0.195000 3.64e-01 2.36e-02
Synthesis of PIPs at the Golgi membrane 15 6.71e-02 1.31e-01 0.36800 0.326000 0.170000 2.88e-02 2.53e-01
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 38 6.72e-02 1.31e-01 0.19900 -0.134000 0.147000 1.53e-01 1.17e-01
KSRP (KHSRP) binds and destabilizes mRNA 16 6.76e-02 1.32e-01 0.35600 0.316000 0.164000 2.87e-02 2.57e-01
IKK complex recruitment mediated by RIP1 14 6.82e-02 1.33e-01 0.37400 0.130000 0.350000 4.00e-01 2.32e-02
Glucagon signaling in metabolic regulation 23 7.00e-02 1.36e-01 0.28900 -0.274000 -0.091700 2.30e-02 4.47e-01
Meiotic recombination 17 7.02e-02 1.36e-01 0.32000 0.320000 0.009430 2.25e-02 9.46e-01
O-linked glycosylation of mucins 21 7.27e-02 1.41e-01 0.26500 -0.140000 0.225000 2.66e-01 7.39e-02
Autodegradation of Cdh1 by Cdh1:APC/C 58 7.33e-02 1.42e-01 0.18400 0.082100 0.165000 2.80e-01 3.03e-02
RNA Polymerase III Transcription Initiation From Type 1 Promoter 26 7.36e-02 1.42e-01 0.27400 0.246000 0.121000 3.00e-02 2.86e-01
RAB geranylgeranylation 41 7.44e-02 1.44e-01 0.20700 0.206000 0.021900 2.29e-02 8.09e-01
Signaling by RAF1 mutants 32 7.57e-02 1.46e-01 0.21300 -0.176000 0.120000 8.58e-02 2.39e-01
Degradation of GLI2 by the proteasome 50 7.59e-02 1.46e-01 0.18800 0.030400 0.186000 7.10e-01 2.32e-02
Regulation of TNFR1 signaling 26 7.62e-02 1.46e-01 0.24700 -0.243000 0.043700 3.23e-02 7.00e-01
Asymmetric localization of PCP proteins 55 7.63e-02 1.46e-01 0.18200 0.044200 0.176000 5.72e-01 2.38e-02
Plasma lipoprotein assembly, remodeling, and clearance 39 7.63e-02 1.46e-01 0.20800 -0.208000 -0.005640 2.47e-02 9.51e-01
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 46 7.67e-02 1.46e-01 0.20500 0.090700 0.183000 2.88e-01 3.15e-02
PECAM1 interactions 10 7.67e-02 1.46e-01 0.37800 -0.250000 0.283000 1.70e-01 1.21e-01
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 62 7.70e-02 1.47e-01 0.16300 -0.005260 0.163000 9.43e-01 2.64e-02
Activation of Matrix Metalloproteinases 11 7.71e-02 1.47e-01 0.36200 -0.307000 0.193000 7.79e-02 2.69e-01
Condensation of Prophase Chromosomes 11 7.74e-02 1.47e-01 0.41800 0.373000 0.188000 3.24e-02 2.80e-01
EPHA-mediated growth cone collapse 13 7.76e-02 1.47e-01 0.34100 -0.103000 0.325000 5.20e-01 4.24e-02
CLEC7A (Dectin-1) induces NFAT activation 10 7.81e-02 1.48e-01 0.44500 -0.330000 -0.299000 7.09e-02 1.01e-01
Degradation of DVL 48 7.83e-02 1.48e-01 0.18900 0.016200 0.188000 8.46e-01 2.45e-02
Sulfur amino acid metabolism 21 7.84e-02 1.48e-01 0.30700 -0.196000 -0.236000 1.19e-01 6.15e-02
Metabolism of nucleotides 74 7.88e-02 1.49e-01 0.15600 -0.151000 -0.035600 2.45e-02 5.97e-01
Metabolism of porphyrins 18 8.01e-02 1.51e-01 0.32400 -0.143000 -0.291000 2.93e-01 3.29e-02
Transport of bile salts and organic acids, metal ions and amine compounds 32 8.07e-02 1.52e-01 0.21200 -0.099100 0.187000 3.32e-01 6.68e-02
TAK1 activates NFkB by phosphorylation and activation of IKKs complex 22 8.16e-02 1.53e-01 0.25800 -0.089800 0.242000 4.66e-01 4.94e-02
Deposition of new CENPA-containing nucleosomes at the centromere 14 8.30e-02 1.55e-01 0.36900 0.308000 0.203000 4.58e-02 1.88e-01
Nucleosome assembly 14 8.30e-02 1.55e-01 0.36900 0.308000 0.203000 4.58e-02 1.88e-01
Initiation of Nuclear Envelope (NE) Reformation 17 8.32e-02 1.55e-01 0.33600 0.196000 0.273000 1.62e-01 5.16e-02
Metabolism of amino acids and derivatives 226 8.33e-02 1.55e-01 0.08080 -0.075100 0.029900 5.32e-02 4.41e-01
Cellular Senescence 117 8.36e-02 1.56e-01 0.12900 0.075000 0.104000 1.63e-01 5.18e-02
Processing of SMDT1 15 8.43e-02 1.57e-01 0.30600 0.149000 -0.267000 3.18e-01 7.30e-02
Zinc transporters 11 8.45e-02 1.57e-01 0.41800 0.304000 0.287000 8.12e-02 9.89e-02
Toll Like Receptor 3 (TLR3) Cascade 82 8.45e-02 1.57e-01 0.13100 -0.071700 0.109000 2.63e-01 8.80e-02
BMAL1:CLOCK,NPAS2 activates circadian gene expression 24 8.50e-02 1.57e-01 0.26900 -0.064100 -0.261000 5.87e-01 2.69e-02
Signaling by NOTCH 149 8.50e-02 1.57e-01 0.09660 -0.063900 0.072400 1.79e-01 1.29e-01
p38MAPK events 12 8.57e-02 1.58e-01 0.36600 -0.366000 -0.006550 2.84e-02 9.69e-01
ZBP1(DAI) mediated induction of type I IFNs 17 8.66e-02 1.60e-01 0.32100 0.094900 0.307000 4.99e-01 2.86e-02
Activation of GABAB receptors 25 8.72e-02 1.60e-01 0.27500 -0.213000 -0.174000 6.54e-02 1.31e-01
GABA B receptor activation 25 8.72e-02 1.60e-01 0.27500 -0.213000 -0.174000 6.54e-02 1.31e-01
Caspase-mediated cleavage of cytoskeletal proteins 11 8.75e-02 1.61e-01 0.35100 -0.257000 0.238000 1.39e-01 1.71e-01
Regulation of PTEN stability and activity 59 8.82e-02 1.62e-01 0.17900 0.107000 0.143000 1.54e-01 5.81e-02
Glutathione conjugation 21 8.87e-02 1.62e-01 0.29700 -0.253000 -0.155000 4.50e-02 2.18e-01
Netrin-1 signaling 38 8.88e-02 1.62e-01 0.21000 -0.206000 -0.040300 2.78e-02 6.67e-01
Regulation of PTEN gene transcription 58 9.05e-02 1.65e-01 0.17200 0.048500 0.165000 5.24e-01 2.97e-02
RNA Polymerase III Chain Elongation 17 9.28e-02 1.69e-01 0.32000 0.297000 0.119000 3.38e-02 3.98e-01
Post NMDA receptor activation events 44 9.29e-02 1.69e-01 0.18800 -0.188000 -0.003140 3.12e-02 9.71e-01
Golgi-to-ER retrograde transport 89 9.32e-02 1.69e-01 0.14500 0.099000 0.105000 1.07e-01 8.63e-02
Collagen degradation 20 9.32e-02 1.69e-01 0.27500 -0.275000 0.015000 3.35e-02 9.07e-01
Oncogenic MAPK signaling 68 9.40e-02 1.70e-01 0.14000 -0.111000 0.085100 1.15e-01 2.26e-01
G alpha (z) signalling events 29 9.49e-02 1.72e-01 0.23500 -0.233000 -0.031500 3.01e-02 7.69e-01
Translesion synthesis by POLK 15 9.74e-02 1.76e-01 0.31800 0.318000 0.003740 3.30e-02 9.80e-01
G alpha (q) signalling events 78 9.75e-02 1.76e-01 0.14600 -0.141000 -0.036100 3.16e-02 5.83e-01
MAPK6/MAPK4 signaling 73 9.85e-02 1.77e-01 0.15000 0.034600 0.146000 6.10e-01 3.17e-02
Regulation of IFNA signaling 12 9.96e-02 1.79e-01 0.34700 -0.037800 0.345000 8.21e-01 3.86e-02
E2F mediated regulation of DNA replication 19 1.00e-01 1.80e-01 0.30600 0.240000 0.190000 6.97e-02 1.52e-01
Transcriptional regulation of white adipocyte differentiation 71 1.02e-01 1.82e-01 0.15100 0.147000 0.034600 3.29e-02 6.15e-01
Cell recruitment (pro-inflammatory response) 12 1.02e-01 1.82e-01 0.34800 -0.020900 0.347000 9.00e-01 3.74e-02
Purinergic signaling in leishmaniasis infection 12 1.02e-01 1.82e-01 0.34800 -0.020900 0.347000 9.00e-01 3.74e-02
GLI3 is processed to GLI3R by the proteasome 50 1.04e-01 1.85e-01 0.18000 0.049000 0.173000 5.50e-01 3.45e-02
MAP2K and MAPK activation 31 1.04e-01 1.86e-01 0.20700 -0.074100 0.193000 4.76e-01 6.34e-02
Activation of BH3-only proteins 25 1.06e-01 1.89e-01 0.22800 -0.090900 0.209000 4.32e-01 7.09e-02
Negative regulation of FGFR3 signaling 19 1.08e-01 1.91e-01 0.28900 0.079500 0.278000 5.49e-01 3.61e-02
rRNA processing in the mitochondrion 11 1.08e-01 1.91e-01 0.36900 -0.037300 -0.367000 8.30e-01 3.51e-02
Signaling by FGFR2 in disease 28 1.08e-01 1.91e-01 0.24600 0.123000 0.213000 2.60e-01 5.17e-02
RNA Polymerase III Abortive And Retractive Initiation 39 1.08e-01 1.91e-01 0.20100 0.195000 0.049000 3.56e-02 5.97e-01
RNA Polymerase III Transcription 39 1.08e-01 1.91e-01 0.20100 0.195000 0.049000 3.56e-02 5.97e-01
Nephrin family interactions 17 1.12e-01 1.97e-01 0.31000 0.137000 0.279000 3.30e-01 4.66e-02
Fc epsilon receptor (FCERI) signaling 104 1.13e-01 1.98e-01 0.12000 0.015100 0.119000 7.91e-01 3.68e-02
Interleukin-3, Interleukin-5 and GM-CSF signaling 28 1.13e-01 1.99e-01 0.21300 -0.078600 0.198000 4.72e-01 6.99e-02
Translesion synthesis by POLI 15 1.14e-01 1.99e-01 0.32100 0.309000 0.089100 3.84e-02 5.50e-01
G alpha (s) signalling events 51 1.14e-01 1.99e-01 0.17800 -0.161000 -0.076400 4.66e-02 3.46e-01
Activation of G protein gated Potassium channels 14 1.14e-01 1.99e-01 0.34600 -0.201000 -0.281000 1.94e-01 6.84e-02
G protein gated Potassium channels 14 1.14e-01 1.99e-01 0.34600 -0.201000 -0.281000 1.94e-01 6.84e-02
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits 14 1.14e-01 1.99e-01 0.34600 -0.201000 -0.281000 1.94e-01 6.84e-02
p75NTR recruits signalling complexes 10 1.15e-01 2.00e-01 0.39300 0.111000 0.377000 5.42e-01 3.91e-02
Anti-inflammatory response favouring Leishmania parasite infection 56 1.18e-01 2.05e-01 0.15600 -0.156000 0.007930 4.35e-02 9.18e-01
Leishmania parasite growth and survival 56 1.18e-01 2.05e-01 0.15600 -0.156000 0.007930 4.35e-02 9.18e-01
Synaptic adhesion-like molecules 12 1.18e-01 2.06e-01 0.35300 -0.344000 -0.078300 3.92e-02 6.39e-01
Beta-catenin phosphorylation cascade 15 1.19e-01 2.06e-01 0.33200 0.248000 0.222000 9.67e-02 1.37e-01
Inositol phosphate metabolism 39 1.19e-01 2.06e-01 0.19900 -0.187000 -0.068300 4.32e-02 4.61e-01
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 13 1.21e-01 2.09e-01 0.34300 0.113000 0.324000 4.82e-01 4.32e-02
Regulation of TP53 Degradation 32 1.21e-01 2.09e-01 0.21300 0.210000 0.037200 3.99e-02 7.16e-01
Regulation of TP53 Expression and Degradation 33 1.21e-01 2.09e-01 0.20500 0.205000 0.009130 4.16e-02 9.28e-01
Hedgehog 'on' state 71 1.23e-01 2.12e-01 0.14700 0.048200 0.138000 4.84e-01 4.40e-02
APC/C:Cdc20 mediated degradation of Securin 59 1.24e-01 2.13e-01 0.16600 0.107000 0.127000 1.54e-01 9.24e-02
PIWI-interacting RNA (piRNA) biogenesis 13 1.24e-01 2.14e-01 0.35300 0.246000 0.254000 1.25e-01 1.13e-01
Activation of BAD and translocation to mitochondria 13 1.25e-01 2.15e-01 0.29800 -0.221000 0.200000 1.69e-01 2.11e-01
MHC class II antigen presentation 71 1.26e-01 2.17e-01 0.15000 0.090400 0.120000 1.89e-01 8.03e-02
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 13 1.27e-01 2.17e-01 0.32300 0.008550 0.322000 9.57e-01 4.42e-02
Negative regulation of FGFR2 signaling 19 1.28e-01 2.19e-01 0.26300 -0.011600 0.263000 9.30e-01 4.74e-02
Vasopressin regulates renal water homeostasis via Aquaporins 27 1.28e-01 2.19e-01 0.24000 -0.209000 -0.119000 6.04e-02 2.86e-01
Transport to the Golgi and subsequent modification 136 1.28e-01 2.19e-01 0.10900 0.066600 0.085900 1.81e-01 8.46e-02
PI3K/AKT Signaling in Cancer 65 1.31e-01 2.23e-01 0.13800 -0.134000 0.033100 6.31e-02 6.45e-01
Regulation of lipid metabolism by PPARalpha 103 1.31e-01 2.23e-01 0.10700 0.094700 -0.048800 9.76e-02 3.93e-01
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 13 1.32e-01 2.24e-01 0.30500 -0.079400 0.295000 6.20e-01 6.56e-02
Cyclin D associated events in G1 41 1.33e-01 2.24e-01 0.19100 0.078100 0.175000 3.87e-01 5.31e-02
G1 Phase 41 1.33e-01 2.24e-01 0.19100 0.078100 0.175000 3.87e-01 5.31e-02
SLC transporter disorders 51 1.33e-01 2.25e-01 0.17500 0.103000 0.141000 2.03e-01 8.12e-02
Chaperone Mediated Autophagy 14 1.33e-01 2.25e-01 0.29700 -0.055000 0.292000 7.22e-01 5.89e-02
Other interleukin signaling 13 1.34e-01 2.25e-01 0.29800 -0.132000 0.267000 4.10e-01 9.57e-02
RIPK1-mediated regulated necrosis 22 1.36e-01 2.28e-01 0.22600 -0.131000 0.184000 2.90e-01 1.36e-01
Regulated Necrosis 22 1.36e-01 2.28e-01 0.22600 -0.131000 0.184000 2.90e-01 1.36e-01
Regulation of necroptotic cell death 22 1.36e-01 2.28e-01 0.22600 -0.131000 0.184000 2.90e-01 1.36e-01
Formation of Incision Complex in GG-NER 39 1.37e-01 2.29e-01 0.17700 0.173000 -0.034100 6.14e-02 7.13e-01
Macroautophagy 98 1.37e-01 2.29e-01 0.10700 0.076300 -0.074500 1.93e-01 2.03e-01
Factors involved in megakaryocyte development and platelet production 80 1.38e-01 2.31e-01 0.12100 -0.114000 0.040100 7.82e-02 5.36e-01
Binding and Uptake of Ligands by Scavenger Receptors 23 1.38e-01 2.31e-01 0.21900 -0.152000 0.157000 2.06e-01 1.92e-01
Keratan sulfate/keratin metabolism 22 1.40e-01 2.33e-01 0.22300 -0.169000 0.146000 1.70e-01 2.38e-01
Neurotransmitter release cycle 22 1.41e-01 2.34e-01 0.24200 0.005280 0.241000 9.66e-01 5.00e-02
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 10 1.41e-01 2.34e-01 0.38600 0.198000 0.331000 2.78e-01 6.98e-02
TRAF6-mediated induction of TAK1 complex within TLR4 complex 10 1.41e-01 2.34e-01 0.38600 0.198000 0.331000 2.78e-01 6.98e-02
Degradation of GLI1 by the proteasome 51 1.42e-01 2.35e-01 0.16800 0.062000 0.156000 4.44e-01 5.42e-02
Inhibition of replication initiation of damaged DNA by RB1/E2F1 12 1.44e-01 2.38e-01 0.35400 0.220000 0.278000 1.88e-01 9.59e-02
Metal ion SLC transporters 17 1.44e-01 2.38e-01 0.28800 0.096100 0.271000 4.93e-01 5.31e-02
Pentose phosphate pathway 12 1.45e-01 2.39e-01 0.34900 0.167000 0.306000 3.16e-01 6.64e-02
Mucopolysaccharidoses 11 1.46e-01 2.40e-01 0.33600 -0.335000 0.008360 5.41e-02 9.62e-01
Processive synthesis on the lagging strand 15 1.46e-01 2.41e-01 0.30800 0.121000 0.283000 4.19e-01 5.80e-02
TCF dependent signaling in response to WNT 134 1.47e-01 2.41e-01 0.10200 0.032400 0.096900 5.19e-01 5.36e-02
Transport of vitamins, nucleosides, and related molecules 24 1.47e-01 2.41e-01 0.21700 -0.205000 0.069700 8.17e-02 5.55e-01
Activation of HOX genes during differentiation 50 1.47e-01 2.41e-01 0.16900 0.154000 0.068300 5.95e-02 4.04e-01
Activation of anterior HOX genes in hindbrain development during early embryogenesis 50 1.47e-01 2.41e-01 0.16900 0.154000 0.068300 5.95e-02 4.04e-01
DNA Damage Bypass 43 1.48e-01 2.42e-01 0.18500 0.155000 0.101000 7.92e-02 2.54e-01
InlB-mediated entry of Listeria monocytogenes into host cell 11 1.49e-01 2.43e-01 0.35900 0.151000 0.325000 3.85e-01 6.18e-02
PPARA activates gene expression 101 1.50e-01 2.45e-01 0.10300 0.087100 -0.055500 1.31e-01 3.36e-01
Spry regulation of FGF signaling 14 1.51e-01 2.45e-01 0.30000 0.024900 0.299000 8.72e-01 5.25e-02
HDMs demethylate histones 19 1.55e-01 2.52e-01 0.27500 0.160000 0.224000 2.27e-01 9.16e-02
Scavenging by Class A Receptors 13 1.56e-01 2.53e-01 0.28200 -0.196000 0.203000 2.22e-01 2.05e-01
Gap-filling DNA repair synthesis and ligation in GG-NER 23 1.59e-01 2.57e-01 0.24900 0.155000 0.195000 1.99e-01 1.05e-01
Interleukin-20 family signaling 12 1.59e-01 2.57e-01 0.31500 -0.315000 0.003040 5.90e-02 9.85e-01
Lysosome Vesicle Biogenesis 27 1.61e-01 2.60e-01 0.22600 0.108000 0.199000 3.32e-01 7.42e-02
Keratan sulfate biosynthesis 17 1.61e-01 2.60e-01 0.24500 -0.198000 0.145000 1.59e-01 3.00e-01
Anchoring of the basal body to the plasma membrane 83 1.62e-01 2.62e-01 0.12200 0.121000 0.016300 5.66e-02 7.98e-01
ERK/MAPK targets 22 1.63e-01 2.63e-01 0.24600 -0.229000 -0.090900 6.37e-02 4.61e-01
GAB1 signalosome 12 1.64e-01 2.65e-01 0.29100 -0.243000 0.160000 1.45e-01 3.38e-01
Constitutive Signaling by Overexpressed ERBB2 10 1.65e-01 2.65e-01 0.35700 0.092200 0.345000 6.14e-01 5.87e-02
Regulation of signaling by CBL 13 1.65e-01 2.65e-01 0.30500 0.033600 0.304000 8.34e-01 5.81e-02
N-glycan trimming in the ER and Calnexin/Calreticulin cycle 31 1.66e-01 2.67e-01 0.21000 0.108000 0.180000 2.99e-01 8.27e-02
Diseases of programmed cell death 24 1.67e-01 2.67e-01 0.21200 -0.051800 0.206000 6.61e-01 8.15e-02
RNA Polymerase I Transcription Initiation 40 1.67e-01 2.67e-01 0.18700 0.144000 0.119000 1.16e-01 1.94e-01
Negative regulators of DDX58/IFIH1 signaling 29 1.67e-01 2.67e-01 0.18600 -0.113000 0.148000 2.94e-01 1.69e-01
ATF6 (ATF6-alpha) activates chaperones 12 1.68e-01 2.69e-01 0.32800 0.106000 0.310000 5.23e-01 6.32e-02
Translesion synthesis by REV1 14 1.69e-01 2.69e-01 0.29700 0.291000 0.061600 5.96e-02 6.90e-01
Diseases associated with O-glycosylation of proteins 33 1.71e-01 2.72e-01 0.18700 -0.187000 -0.002340 6.34e-02 9.81e-01
Signaling by TGFB family members 86 1.71e-01 2.72e-01 0.12300 0.047000 0.114000 4.52e-01 6.82e-02
Downstream signal transduction 27 1.74e-01 2.76e-01 0.19300 -0.176000 0.080800 1.14e-01 4.68e-01
Vitamin B5 (pantothenate) metabolism 15 1.74e-01 2.76e-01 0.25800 0.120000 -0.228000 4.21e-01 1.26e-01
HDR through Single Strand Annealing (SSA) 30 1.75e-01 2.77e-01 0.19800 0.197000 0.024000 6.21e-02 8.20e-01
Translation of Replicase and Assembly of the Replication Transcription Complex 11 1.75e-01 2.77e-01 0.29700 0.238000 -0.178000 1.71e-01 3.07e-01
Regulation of PLK1 Activity at G2/M Transition 74 1.76e-01 2.78e-01 0.12800 0.125000 0.024400 6.24e-02 7.17e-01
Transcription of E2F targets under negative control by DREAM complex 17 1.76e-01 2.78e-01 0.28000 0.231000 0.159000 9.99e-02 2.55e-01
Removal of the Flap Intermediate 14 1.76e-01 2.78e-01 0.30800 0.167000 0.259000 2.79e-01 9.39e-02
Formation of the beta-catenin:TCF transactivating complex 28 1.79e-01 2.82e-01 0.21900 0.158000 0.151000 1.47e-01 1.67e-01
CS/DS degradation 10 1.80e-01 2.83e-01 0.31100 -0.265000 0.163000 1.47e-01 3.72e-01
TNFR1-induced NFkappaB signaling pathway 21 1.82e-01 2.86e-01 0.23500 -0.233000 -0.030500 6.51e-02 8.09e-01
Signaling by Leptin 10 1.83e-01 2.87e-01 0.35600 -0.320000 -0.157000 8.02e-02 3.90e-01
CREB1 phosphorylation through the activation of Adenylate Cyclase 10 1.84e-01 2.87e-01 0.32000 -0.312000 0.071400 8.75e-02 6.96e-01
Interleukin-6 family signaling 16 1.84e-01 2.87e-01 0.25300 -0.246000 0.058700 8.88e-02 6.84e-01
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 55 1.87e-01 2.91e-01 0.14600 0.031600 0.143000 6.86e-01 6.74e-02
Meiotic synapsis 22 1.87e-01 2.91e-01 0.22600 0.225000 0.019800 6.79e-02 8.73e-01
mRNA decay by 3' to 5' exoribonuclease 15 1.88e-01 2.92e-01 0.29400 0.232000 0.180000 1.20e-01 2.27e-01
PKMTs methylate histone lysines 37 1.88e-01 2.92e-01 0.16300 0.152000 -0.057200 1.09e-01 5.47e-01
ROS and RNS production in phagocytes 20 1.88e-01 2.92e-01 0.22700 -0.036600 0.224000 7.77e-01 8.30e-02
FOXO-mediated transcription 51 1.90e-01 2.95e-01 0.15900 -0.121000 -0.103000 1.35e-01 2.02e-01
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein 66 1.92e-01 2.98e-01 0.12200 -0.037900 0.116000 5.95e-01 1.05e-01
Metabolism of cofactors 16 1.93e-01 2.98e-01 0.28100 -0.152000 -0.236000 2.94e-01 1.02e-01
Intraflagellar transport 35 1.93e-01 2.98e-01 0.16200 0.122000 -0.107000 2.13e-01 2.74e-01
Cargo trafficking to the periciliary membrane 42 1.96e-01 3.03e-01 0.15000 0.137000 -0.059700 1.23e-01 5.04e-01
Regulation of TP53 Activity through Acetylation 28 1.98e-01 3.05e-01 0.21200 0.162000 0.138000 1.39e-01 2.08e-01
Ovarian tumor domain proteases 31 1.98e-01 3.05e-01 0.19700 0.080000 0.180000 4.41e-01 8.33e-02
Peptide ligand-binding receptors 22 1.99e-01 3.06e-01 0.20700 -0.071500 0.195000 5.62e-01 1.14e-01
MyD88 dependent cascade initiated on endosome 77 1.99e-01 3.06e-01 0.11000 -0.048000 0.098900 4.68e-01 1.34e-01
Toll Like Receptor 7/8 (TLR7/8) Cascade 77 1.99e-01 3.06e-01 0.11000 -0.048000 0.098900 4.68e-01 1.34e-01
Notch-HLH transcription pathway 24 2.00e-01 3.06e-01 0.20600 -0.206000 0.014100 8.10e-02 9.05e-01
TGF-beta receptor signaling activates SMADs 29 2.07e-01 3.17e-01 0.20200 0.095000 0.179000 3.76e-01 9.61e-02
Ca2+ pathway 45 2.07e-01 3.17e-01 0.15500 -0.022700 -0.153000 7.92e-01 7.62e-02
Activation of AMPK downstream of NMDARs 10 2.10e-01 3.20e-01 0.34700 -0.282000 -0.203000 1.23e-01 2.67e-01
Cargo recognition for clathrin-mediated endocytosis 73 2.10e-01 3.20e-01 0.12600 0.116000 0.050700 8.84e-02 4.54e-01
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA 15 2.10e-01 3.20e-01 0.27700 0.254000 0.112000 8.85e-02 4.55e-01
Signalling to ERKs 29 2.12e-01 3.22e-01 0.17700 -0.059000 0.167000 5.82e-01 1.19e-01
Assembly and cell surface presentation of NMDA receptors 13 2.16e-01 3.28e-01 0.28100 -0.280000 -0.027200 8.08e-02 8.65e-01
Negative regulation of MAPK pathway 39 2.20e-01 3.33e-01 0.16800 0.057900 0.158000 5.32e-01 8.79e-02
ER to Golgi Anterograde Transport 114 2.20e-01 3.34e-01 0.09970 0.090800 0.041400 9.51e-02 4.47e-01
YAP1- and WWTR1 (TAZ)-stimulated gene expression 11 2.21e-01 3.35e-01 0.30000 -0.300000 -0.008940 8.53e-02 9.59e-01
DNA Damage Recognition in GG-NER 34 2.26e-01 3.42e-01 0.17000 0.170000 0.008360 8.69e-02 9.33e-01
Base Excision Repair 43 2.27e-01 3.42e-01 0.16400 0.109000 0.122000 2.15e-01 1.65e-01
Dual Incision in GG-NER 38 2.28e-01 3.43e-01 0.16800 0.159000 0.056000 9.10e-02 5.51e-01
Frs2-mediated activation 10 2.28e-01 3.43e-01 0.33100 0.138000 0.301000 4.49e-01 9.93e-02
Signaling by FGFR1 34 2.30e-01 3.46e-01 0.18100 0.089000 0.158000 3.70e-01 1.12e-01
Prolonged ERK activation events 12 2.32e-01 3.49e-01 0.30800 0.220000 0.216000 1.88e-01 1.96e-01
Erythropoietin activates RAS 11 2.33e-01 3.49e-01 0.29900 0.037000 0.297000 8.32e-01 8.80e-02
Circadian Clock 63 2.33e-01 3.49e-01 0.13400 -0.092300 -0.097800 2.06e-01 1.80e-01
Signaling by FGFR3 29 2.33e-01 3.49e-01 0.19500 0.099200 0.168000 3.56e-01 1.17e-01
Interleukin receptor SHC signaling 15 2.35e-01 3.51e-01 0.24300 -0.044200 0.239000 7.67e-01 1.09e-01
MTOR signalling 40 2.36e-01 3.52e-01 0.16500 -0.079200 -0.145000 3.86e-01 1.12e-01
Cristae formation 10 2.37e-01 3.54e-01 0.29700 0.050400 -0.293000 7.83e-01 1.09e-01
Regulation of IFNG signaling 13 2.38e-01 3.54e-01 0.28800 0.136000 0.255000 3.98e-01 1.12e-01
Platelet sensitization by LDL 13 2.39e-01 3.55e-01 0.28600 0.118000 0.260000 4.61e-01 1.04e-01
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 76 2.39e-01 3.55e-01 0.10400 -0.051300 0.090100 4.40e-01 1.75e-01
Cytochrome P450 - arranged by substrate type 18 2.39e-01 3.55e-01 0.24800 -0.191000 -0.159000 1.62e-01 2.42e-01
FCERI mediated Ca+2 mobilization 18 2.40e-01 3.56e-01 0.24100 -0.223000 -0.091500 1.01e-01 5.02e-01
Fanconi Anemia Pathway 25 2.41e-01 3.57e-01 0.20200 0.193000 0.059600 9.50e-02 6.06e-01
Interleukin-15 signaling 11 2.42e-01 3.57e-01 0.27300 -0.247000 0.115000 1.56e-01 5.10e-01
Nicotinate metabolism 20 2.43e-01 3.58e-01 0.23300 -0.128000 -0.195000 3.22e-01 1.32e-01
Purine ribonucleoside monophosphate biosynthesis 12 2.46e-01 3.63e-01 0.27100 0.024000 -0.270000 8.86e-01 1.05e-01
Transcriptional regulation of pluripotent stem cells 11 2.47e-01 3.64e-01 0.27000 -0.120000 0.242000 4.92e-01 1.65e-01
DARPP-32 events 21 2.49e-01 3.67e-01 0.22200 -0.202000 -0.090100 1.09e-01 4.75e-01
Cargo concentration in the ER 21 2.51e-01 3.68e-01 0.21000 0.209000 0.019100 9.73e-02 8.80e-01
Interleukin-2 family signaling 22 2.51e-01 3.68e-01 0.18900 -0.168000 0.087700 1.73e-01 4.77e-01
Synthesis of PIPs at the late endosome membrane 10 2.51e-01 3.68e-01 0.28200 0.257000 -0.116000 1.59e-01 5.27e-01
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 29 2.52e-01 3.69e-01 0.17200 0.021200 -0.171000 8.44e-01 1.11e-01
Termination of translesion DNA synthesis 28 2.52e-01 3.69e-01 0.19300 0.091800 0.170000 4.01e-01 1.21e-01
Nucleobase biosynthesis 15 2.53e-01 3.70e-01 0.23900 0.031700 -0.236000 8.32e-01 1.13e-01
Constitutive Signaling by Aberrant PI3K in Cancer 38 2.53e-01 3.70e-01 0.14300 -0.122000 0.074500 1.93e-01 4.28e-01
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 16 2.54e-01 3.70e-01 0.24500 0.239000 0.055800 9.86e-02 7.00e-01
Metabolism of folate and pterines 13 2.55e-01 3.71e-01 0.26800 -0.265000 -0.042900 9.82e-02 7.89e-01
Molecules associated with elastic fibres 25 2.59e-01 3.76e-01 0.19300 0.033300 0.190000 7.74e-01 1.00e-01
Amino acids regulate mTORC1 45 2.59e-01 3.76e-01 0.13300 -0.044700 0.125000 6.04e-01 1.47e-01
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 18 2.60e-01 3.76e-01 0.20800 -0.084400 0.190000 5.36e-01 1.63e-01
Neurodegenerative Diseases 18 2.60e-01 3.76e-01 0.20800 -0.084400 0.190000 5.36e-01 1.63e-01
AURKA Activation by TPX2 62 2.60e-01 3.77e-01 0.12300 0.121000 0.022800 1.01e-01 7.57e-01
Early Phase of HIV Life Cycle 11 2.64e-01 3.82e-01 0.30300 0.149000 0.264000 3.93e-01 1.30e-01
Plasma lipoprotein remodeling 11 2.69e-01 3.89e-01 0.28700 -0.282000 -0.051300 1.05e-01 7.68e-01
Synthesis of PIPs at the early endosome membrane 16 2.73e-01 3.94e-01 0.25000 0.152000 0.199000 2.92e-01 1.69e-01
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function 30 2.74e-01 3.95e-01 0.16300 0.161000 -0.026600 1.28e-01 8.01e-01
Phospholipid metabolism 150 2.78e-01 4.00e-01 0.08070 -0.038400 -0.071000 4.19e-01 1.35e-01
EGFR downregulation 22 2.78e-01 4.00e-01 0.21300 0.154000 0.147000 2.12e-01 2.32e-01
MyD88 cascade initiated on plasma membrane 75 2.80e-01 4.01e-01 0.09740 -0.067600 0.070100 3.12e-01 2.95e-01
Toll Like Receptor 10 (TLR10) Cascade 75 2.80e-01 4.01e-01 0.09740 -0.067600 0.070100 3.12e-01 2.95e-01
Toll Like Receptor 5 (TLR5) Cascade 75 2.80e-01 4.01e-01 0.09740 -0.067600 0.070100 3.12e-01 2.95e-01
TICAM1, RIP1-mediated IKK complex recruitment 14 2.82e-01 4.02e-01 0.26000 0.112000 0.235000 4.70e-01 1.29e-01
Misspliced GSK3beta mutants stabilize beta-catenin 14 2.83e-01 4.02e-01 0.26500 0.203000 0.170000 1.89e-01 2.71e-01
S33 mutants of beta-catenin aren't phosphorylated 14 2.83e-01 4.02e-01 0.26500 0.203000 0.170000 1.89e-01 2.71e-01
S37 mutants of beta-catenin aren't phosphorylated 14 2.83e-01 4.02e-01 0.26500 0.203000 0.170000 1.89e-01 2.71e-01
S45 mutants of beta-catenin aren't phosphorylated 14 2.83e-01 4.02e-01 0.26500 0.203000 0.170000 1.89e-01 2.71e-01
T41 mutants of beta-catenin aren't phosphorylated 14 2.83e-01 4.02e-01 0.26500 0.203000 0.170000 1.89e-01 2.71e-01
phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex 14 2.83e-01 4.02e-01 0.26500 0.203000 0.170000 1.89e-01 2.71e-01
Cellular response to hypoxia 62 2.84e-01 4.02e-01 0.12100 0.034500 0.116000 6.39e-01 1.15e-01
Processive synthesis on the C-strand of the telomere 19 2.84e-01 4.03e-01 0.22400 0.109000 0.195000 4.09e-01 1.41e-01
Thrombin signalling through proteinase activated receptors (PARs) 20 2.85e-01 4.04e-01 0.19400 -0.049800 0.187000 7.00e-01 1.47e-01
Downregulation of TGF-beta receptor signaling 24 2.86e-01 4.04e-01 0.20100 0.115000 0.164000 3.29e-01 1.64e-01
Negative regulation of FGFR4 signaling 19 2.90e-01 4.10e-01 0.20400 -0.010300 0.204000 9.38e-01 1.25e-01
Glutamate binding, activation of AMPA receptors and synaptic plasticity 19 2.91e-01 4.10e-01 0.19700 -0.189000 0.054100 1.53e-01 6.83e-01
Trafficking of AMPA receptors 19 2.91e-01 4.10e-01 0.19700 -0.189000 0.054100 1.53e-01 6.83e-01
Apoptotic factor-mediated response 13 2.92e-01 4.11e-01 0.24500 -0.014800 0.245000 9.27e-01 1.26e-01
Constitutive Signaling by AKT1 E17K in Cancer 26 2.94e-01 4.11e-01 0.18300 -0.177000 -0.046200 1.19e-01 6.84e-01
Regulation of insulin secretion 47 2.94e-01 4.11e-01 0.13500 -0.132000 -0.030200 1.19e-01 7.20e-01
AMER1 mutants destabilize the destruction complex 13 2.94e-01 4.11e-01 0.27100 0.189000 0.194000 2.38e-01 2.27e-01
APC truncation mutants have impaired AXIN binding 13 2.94e-01 4.11e-01 0.27100 0.189000 0.194000 2.38e-01 2.27e-01
AXIN missense mutants destabilize the destruction complex 13 2.94e-01 4.11e-01 0.27100 0.189000 0.194000 2.38e-01 2.27e-01
AXIN mutants destabilize the destruction complex, activating WNT signaling 13 2.94e-01 4.11e-01 0.27100 0.189000 0.194000 2.38e-01 2.27e-01
Truncations of AMER1 destabilize the destruction complex 13 2.94e-01 4.11e-01 0.27100 0.189000 0.194000 2.38e-01 2.27e-01
truncated APC mutants destabilize the destruction complex 13 2.94e-01 4.11e-01 0.27100 0.189000 0.194000 2.38e-01 2.27e-01
WNT5A-dependent internalization of FZD4 13 2.96e-01 4.13e-01 0.23000 -0.196000 0.121000 2.22e-01 4.51e-01
Metabolism of nitric oxide: NOS3 activation and regulation 13 3.00e-01 4.16e-01 0.22700 -0.141000 0.178000 3.77e-01 2.66e-01
Competing endogenous RNAs (ceRNAs) regulate PTEN translation 10 3.00e-01 4.16e-01 0.27300 0.041200 -0.270000 8.22e-01 1.40e-01
Costimulation by the CD28 family 39 3.00e-01 4.17e-01 0.14000 -0.009620 0.140000 9.17e-01 1.31e-01
Acyl chain remodelling of PS 10 3.01e-01 4.17e-01 0.30600 0.217000 0.215000 2.34e-01 2.38e-01
Signaling by ERBB2 37 3.01e-01 4.17e-01 0.13600 -0.070900 0.116000 4.56e-01 2.24e-01
ABC transporter disorders 56 3.03e-01 4.19e-01 0.12400 0.034800 0.119000 6.52e-01 1.25e-01
Interleukin-6 signaling 10 3.06e-01 4.23e-01 0.25700 -0.202000 0.159000 2.68e-01 3.85e-01
Signaling by Hippo 18 3.07e-01 4.24e-01 0.22300 0.106000 0.196000 4.35e-01 1.51e-01
tRNA processing in the mitochondrion 11 3.09e-01 4.25e-01 0.26000 0.021200 -0.259000 9.03e-01 1.37e-01
Negative regulation of FGFR1 signaling 19 3.09e-01 4.25e-01 0.20500 0.027500 0.203000 8.36e-01 1.25e-01
Glycosphingolipid metabolism 32 3.10e-01 4.27e-01 0.14300 -0.108000 0.093800 2.92e-01 3.59e-01
RAS processing 18 3.13e-01 4.31e-01 0.19000 -0.156000 0.109000 2.53e-01 4.23e-01
Recycling pathway of L1 23 3.14e-01 4.31e-01 0.17400 -0.041700 0.169000 7.29e-01 1.60e-01
APC-Cdc20 mediated degradation of Nek2A 21 3.14e-01 4.31e-01 0.19200 0.192000 0.018800 1.29e-01 8.81e-01
Interleukin-17 signaling 62 3.17e-01 4.34e-01 0.10600 -0.102000 0.026600 1.64e-01 7.18e-01
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 34 3.19e-01 4.36e-01 0.16200 0.112000 0.117000 2.58e-01 2.40e-01
MyD88:MAL(TIRAP) cascade initiated on plasma membrane 81 3.20e-01 4.36e-01 0.08890 -0.054900 0.069900 3.94e-01 2.78e-01
Toll Like Receptor 2 (TLR2) Cascade 81 3.20e-01 4.36e-01 0.08890 -0.054900 0.069900 3.94e-01 2.78e-01
Toll Like Receptor TLR1:TLR2 Cascade 81 3.20e-01 4.36e-01 0.08890 -0.054900 0.069900 3.94e-01 2.78e-01
Toll Like Receptor TLR6:TLR2 Cascade 81 3.20e-01 4.36e-01 0.08890 -0.054900 0.069900 3.94e-01 2.78e-01
SHC1 events in ERBB2 signaling 15 3.22e-01 4.39e-01 0.20500 -0.163000 0.125000 2.75e-01 4.01e-01
Uptake and actions of bacterial toxins 21 3.23e-01 4.39e-01 0.17300 -0.127000 0.118000 3.15e-01 3.51e-01
DNA Double Strand Break Response 37 3.23e-01 4.39e-01 0.15400 0.110000 0.108000 2.47e-01 2.55e-01
Platelet homeostasis 51 3.24e-01 4.39e-01 0.12400 -0.122000 -0.023800 1.33e-01 7.69e-01
Telomere C-strand synthesis initiation 11 3.25e-01 4.41e-01 0.26500 0.261000 0.047200 1.34e-01 7.86e-01
Resolution of Abasic Sites (AP sites) 36 3.26e-01 4.42e-01 0.15400 0.082900 0.130000 3.90e-01 1.76e-01
Signal transduction by L1 20 3.27e-01 4.42e-01 0.17600 -0.130000 0.119000 3.13e-01 3.58e-01
Metalloprotease DUBs 15 3.28e-01 4.43e-01 0.22700 0.223000 0.045700 1.36e-01 7.59e-01
ADORA2B mediated anti-inflammatory cytokines production 38 3.31e-01 4.46e-01 0.14400 -0.139000 -0.036200 1.39e-01 7.00e-01
Beta-catenin independent WNT signaling 117 3.31e-01 4.46e-01 0.07730 -0.008240 0.076900 8.78e-01 1.52e-01
Membrane binding and targetting of GAG proteins 10 3.32e-01 4.47e-01 0.26200 -0.032400 0.260000 8.59e-01 1.55e-01
Synthesis And Processing Of GAG, GAGPOL Polyproteins 10 3.32e-01 4.47e-01 0.26200 -0.032400 0.260000 8.59e-01 1.55e-01
Mitophagy 24 3.34e-01 4.49e-01 0.16000 0.134000 -0.087800 2.56e-01 4.57e-01
Synthesis of PA 21 3.34e-01 4.49e-01 0.20100 -0.132000 -0.152000 2.95e-01 2.28e-01
Intra-Golgi traffic 38 3.37e-01 4.52e-01 0.14700 0.128000 0.073200 1.72e-01 4.35e-01
Toll Like Receptor 9 (TLR9) Cascade 80 3.38e-01 4.53e-01 0.09030 -0.023600 0.087200 7.16e-01 1.79e-01
Trafficking of GluR2-containing AMPA receptors 10 3.40e-01 4.54e-01 0.24500 -0.162000 0.184000 3.75e-01 3.14e-01
Regulation of RUNX2 expression and activity 61 3.46e-01 4.62e-01 0.11300 0.041100 0.105000 5.79e-01 1.55e-01
Oxidative Stress Induced Senescence 59 3.46e-01 4.62e-01 0.11800 0.068800 0.095800 3.61e-01 2.04e-01
eNOS activation 10 3.48e-01 4.64e-01 0.24200 -0.183000 0.159000 3.17e-01 3.84e-01
IL-6-type cytokine receptor ligand interactions 10 3.48e-01 4.64e-01 0.28100 -0.253000 -0.122000 1.67e-01 5.04e-01
Signaling by EGFR 41 3.53e-01 4.70e-01 0.13600 0.043400 0.128000 6.31e-01 1.55e-01
Apoptotic cleavage of cellular proteins 27 3.55e-01 4.71e-01 0.14700 -0.126000 0.075900 2.56e-01 4.95e-01
Diseases associated with N-glycosylation of proteins 16 3.55e-01 4.71e-01 0.22300 0.130000 0.182000 3.68e-01 2.09e-01
ER Quality Control Compartment (ERQC) 18 3.56e-01 4.71e-01 0.20800 0.101000 0.182000 4.58e-01 1.81e-01
NOTCH3 Activation and Transmission of Signal to the Nucleus 21 3.57e-01 4.72e-01 0.17800 -0.178000 0.003170 1.58e-01 9.80e-01
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 10 3.58e-01 4.73e-01 0.25000 -0.245000 0.050400 1.80e-01 7.83e-01
Ras activation upon Ca2+ influx through NMDA receptor 13 3.59e-01 4.74e-01 0.24500 -0.209000 -0.128000 1.92e-01 4.24e-01
G1/S-Specific Transcription 21 3.61e-01 4.76e-01 0.19500 0.138000 0.137000 2.75e-01 2.76e-01
Phase II - Conjugation of compounds 46 3.61e-01 4.76e-01 0.13000 -0.067500 -0.111000 4.29e-01 1.93e-01
Centrosome maturation 71 3.64e-01 4.79e-01 0.09340 0.091400 -0.018800 1.84e-01 7.85e-01
Recruitment of mitotic centrosome proteins and complexes 71 3.64e-01 4.79e-01 0.09340 0.091400 -0.018800 1.84e-01 7.85e-01
Role of phospholipids in phagocytosis 14 3.65e-01 4.79e-01 0.23700 -0.165000 -0.170000 2.85e-01 2.71e-01
LDL clearance 14 3.65e-01 4.79e-01 0.22000 0.022900 0.219000 8.82e-01 1.57e-01
Energy dependent regulation of mTOR by LKB1-AMPK 29 3.65e-01 4.79e-01 0.16200 -0.077500 -0.142000 4.70e-01 1.85e-01
Golgi Cisternae Pericentriolar Stack Reorganization 11 3.68e-01 4.82e-01 0.26600 0.189000 0.188000 2.79e-01 2.81e-01
Signaling by SCF-KIT 32 3.68e-01 4.82e-01 0.13600 -0.044100 0.128000 6.66e-01 2.10e-01
MicroRNA (miRNA) biogenesis 22 3.69e-01 4.82e-01 0.16500 0.161000 -0.038500 1.92e-01 7.55e-01
Carboxyterminal post-translational modifications of tubulin 21 3.70e-01 4.83e-01 0.16600 -0.153000 0.063500 2.24e-01 6.14e-01
Inactivation of APC/C via direct inhibition of the APC/C complex 19 3.73e-01 4.87e-01 0.17700 0.171000 -0.042700 1.96e-01 7.47e-01
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 19 3.73e-01 4.87e-01 0.17700 0.171000 -0.042700 1.96e-01 7.47e-01
Receptor Mediated Mitophagy 11 3.75e-01 4.88e-01 0.22600 0.205000 -0.096800 2.40e-01 5.78e-01
Pre-NOTCH Expression and Processing 45 3.75e-01 4.88e-01 0.11100 -0.090400 0.063800 2.94e-01 4.60e-01
Signaling by WNT 202 3.77e-01 4.90e-01 0.05890 0.014600 0.057000 7.22e-01 1.64e-01
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism 11 3.78e-01 4.90e-01 0.26000 -0.140000 -0.219000 4.20e-01 2.09e-01
Signaling by PDGFR in disease 17 3.79e-01 4.91e-01 0.20700 0.092700 0.185000 5.08e-01 1.87e-01
TRAF6 mediated NF-kB activation 19 3.79e-01 4.91e-01 0.16900 -0.134000 0.103000 3.11e-01 4.38e-01
TBC/RABGAPs 39 3.82e-01 4.94e-01 0.13600 0.056800 0.123000 5.40e-01 1.83e-01
NR1H2 and NR1H3-mediated signaling 34 3.82e-01 4.94e-01 0.14900 -0.098100 -0.112000 3.23e-01 2.61e-01
TP53 Regulates Metabolic Genes 79 3.83e-01 4.95e-01 0.09760 -0.068700 -0.069300 2.92e-01 2.88e-01
Purine salvage 13 3.88e-01 5.00e-01 0.21100 -0.207000 0.040100 1.96e-01 8.02e-01
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 23 3.94e-01 5.07e-01 0.17000 0.045800 0.163000 7.04e-01 1.75e-01
SHC-mediated cascade:FGFR2 10 3.94e-01 5.07e-01 0.23200 -0.091500 0.213000 6.16e-01 2.43e-01
Late endosomal microautophagy 23 3.95e-01 5.08e-01 0.15100 -0.127000 0.082000 2.94e-01 4.96e-01
NOTCH2 Activation and Transmission of Signal to the Nucleus 16 3.96e-01 5.09e-01 0.21000 -0.177000 -0.114000 2.21e-01 4.28e-01
Signaling by Nuclear Receptors 175 4.01e-01 5.15e-01 0.06220 0.058200 0.022000 1.86e-01 6.18e-01
Downregulation of SMAD2/3:SMAD4 transcriptional activity 19 4.02e-01 5.15e-01 0.18900 0.171000 0.081300 1.97e-01 5.40e-01
PI Metabolism 69 4.04e-01 5.17e-01 0.09900 0.090200 0.040800 1.96e-01 5.58e-01
Regulation of PTEN mRNA translation 11 4.05e-01 5.18e-01 0.21800 0.090400 -0.198000 6.04e-01 2.56e-01
SHC-mediated cascade:FGFR3 10 4.05e-01 5.18e-01 0.25500 0.081400 0.242000 6.56e-01 1.85e-01
Regulation of cholesterol biosynthesis by SREBP (SREBF) 53 4.07e-01 5.20e-01 0.11500 -0.089500 -0.072000 2.61e-01 3.65e-01
Loss of Nlp from mitotic centrosomes 60 4.09e-01 5.21e-01 0.10100 0.099900 0.014800 1.81e-01 8.43e-01
Loss of proteins required for interphase microtubule organization from the centrosome 60 4.09e-01 5.21e-01 0.10100 0.099900 0.014800 1.81e-01 8.43e-01
Glycolysis 55 4.12e-01 5.24e-01 0.10100 0.101000 -0.009580 1.98e-01 9.02e-01
Other semaphorin interactions 14 4.13e-01 5.25e-01 0.22000 -0.183000 -0.123000 2.37e-01 4.26e-01
Miscellaneous transport and binding events 16 4.15e-01 5.27e-01 0.17600 0.150000 -0.092500 2.99e-01 5.22e-01
Activation of kainate receptors upon glutamate binding 17 4.17e-01 5.28e-01 0.19400 -0.180000 -0.072200 1.98e-01 6.06e-01
Adherens junctions interactions 11 4.17e-01 5.28e-01 0.21900 -0.213000 0.050000 2.21e-01 7.74e-01
MAP kinase activation 59 4.18e-01 5.30e-01 0.09440 -0.091500 0.023400 2.25e-01 7.56e-01
RET signaling 28 4.21e-01 5.32e-01 0.13900 -0.138000 0.017000 2.07e-01 8.77e-01
Signaling by NOTCH3 38 4.21e-01 5.32e-01 0.11800 -0.116000 0.023200 2.18e-01 8.05e-01
Disassembly of the destruction complex and recruitment of AXIN to the membrane 25 4.23e-01 5.34e-01 0.15900 0.056500 0.148000 6.25e-01 2.00e-01
Adenylate cyclase inhibitory pathway 11 4.24e-01 5.34e-01 0.23100 -0.228000 -0.037900 1.90e-01 8.28e-01
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 10 4.26e-01 5.37e-01 0.22000 0.194000 -0.104000 2.88e-01 5.68e-01
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 11 4.28e-01 5.38e-01 0.23400 0.059300 0.226000 7.34e-01 1.95e-01
Uptake and function of anthrax toxins 11 4.32e-01 5.43e-01 0.23300 -0.224000 -0.065900 1.99e-01 7.05e-01
AKT phosphorylates targets in the cytosol 14 4.34e-01 5.45e-01 0.18300 -0.148000 0.108000 3.39e-01 4.86e-01
VEGFR2 mediated vascular permeability 23 4.34e-01 5.45e-01 0.14300 -0.078900 0.119000 5.13e-01 3.23e-01
APC/C:Cdc20 mediated degradation of Cyclin B 20 4.41e-01 5.52e-01 0.16300 0.163000 0.000931 2.07e-01 9.94e-01
Nucleobase catabolism 21 4.41e-01 5.52e-01 0.17300 -0.146000 -0.091800 2.47e-01 4.66e-01
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression 15 4.45e-01 5.57e-01 0.19700 0.061000 0.187000 6.83e-01 2.09e-01
activated TAK1 mediates p38 MAPK activation 17 4.48e-01 5.60e-01 0.17200 -0.171000 0.019300 2.23e-01 8.90e-01
Defective B3GALTL causes Peters-plus syndrome (PpS) 24 4.51e-01 5.62e-01 0.15700 -0.143000 -0.065600 2.26e-01 5.78e-01
Signaling by Insulin receptor 48 4.52e-01 5.63e-01 0.11000 0.041700 0.102000 6.18e-01 2.21e-01
RNA Polymerase III Transcription Termination 22 4.53e-01 5.64e-01 0.15900 0.154000 0.040200 2.11e-01 7.45e-01
Autophagy 108 4.54e-01 5.64e-01 0.06410 0.047100 -0.043500 3.99e-01 4.37e-01
Selective autophagy 51 4.54e-01 5.64e-01 0.09540 0.033000 -0.089500 6.84e-01 2.69e-01
TNF signaling 34 4.55e-01 5.65e-01 0.12300 -0.123000 -0.000908 2.15e-01 9.93e-01
O-glycosylation of TSR domain-containing proteins 25 4.56e-01 5.65e-01 0.14900 -0.144000 -0.038600 2.12e-01 7.38e-01
Signaling by PDGFRA extracellular domain mutants 11 4.58e-01 5.67e-01 0.23000 0.098600 0.208000 5.72e-01 2.33e-01
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants 11 4.58e-01 5.67e-01 0.23000 0.098600 0.208000 5.72e-01 2.33e-01
Removal of the Flap Intermediate from the C-strand 17 4.59e-01 5.67e-01 0.18900 0.138000 0.129000 3.25e-01 3.56e-01
Activation of SMO 12 4.62e-01 5.71e-01 0.22100 -0.189000 -0.115000 2.57e-01 4.91e-01
Repression of WNT target genes 11 4.64e-01 5.73e-01 0.22200 0.057900 0.215000 7.40e-01 2.18e-01
VEGFR2 mediated cell proliferation 16 4.69e-01 5.78e-01 0.19100 -0.159000 -0.105000 2.72e-01 4.66e-01
Plasma lipoprotein clearance 21 4.72e-01 5.81e-01 0.14100 -0.110000 0.088600 3.83e-01 4.83e-01
Apoptotic execution phase 35 4.73e-01 5.81e-01 0.11200 -0.039600 0.105000 6.85e-01 2.84e-01
RHO GTPases activate KTN1 10 4.76e-01 5.85e-01 0.23600 0.107000 0.210000 5.60e-01 2.49e-01
Phosphorylation of the APC/C 18 4.77e-01 5.85e-01 0.15400 0.139000 -0.066000 3.08e-01 6.28e-01
Retrograde neurotrophin signalling 11 4.77e-01 5.85e-01 0.21300 0.022800 0.212000 8.96e-01 2.25e-01
Arachidonic acid metabolism 19 4.77e-01 5.85e-01 0.17100 -0.153000 -0.074700 2.47e-01 5.73e-01
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 19 4.79e-01 5.87e-01 0.14700 0.116000 -0.090400 3.81e-01 4.96e-01
Signaling by EGFR in Cancer 18 4.80e-01 5.87e-01 0.17800 0.112000 0.138000 4.13e-01 3.09e-01
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks 36 4.83e-01 5.89e-01 0.12600 0.085300 0.092200 3.76e-01 3.39e-01
MAPK targets/ Nuclear events mediated by MAP kinases 31 4.83e-01 5.89e-01 0.12800 -0.125000 -0.024700 2.28e-01 8.12e-01
Synthesis of pyrophosphates in the cytosol 10 4.83e-01 5.89e-01 0.21600 0.007670 -0.216000 9.67e-01 2.38e-01
Recruitment of NuMA to mitotic centrosomes 70 4.84e-01 5.89e-01 0.07860 0.075000 -0.023500 2.78e-01 7.34e-01
Interconversion of nucleotide di- and triphosphates 21 4.84e-01 5.89e-01 0.13900 -0.096500 0.099700 4.44e-01 4.29e-01
Cell-cell junction organization 23 4.91e-01 5.96e-01 0.13100 -0.093800 0.091800 4.36e-01 4.46e-01
Rap1 signalling 14 4.92e-01 5.98e-01 0.19400 0.078500 0.177000 6.11e-01 2.52e-01
Metabolism of steroids 93 4.93e-01 5.98e-01 0.07250 -0.071600 -0.011700 2.34e-01 8.46e-01
Constitutive Signaling by NOTCH1 HD Domain Mutants 11 4.96e-01 6.00e-01 0.21600 -0.202000 -0.075600 2.46e-01 6.64e-01
Signaling by NOTCH1 HD Domain Mutants in Cancer 11 4.96e-01 6.00e-01 0.21600 -0.202000 -0.075600 2.46e-01 6.64e-01
Signaling by Hedgehog 114 4.98e-01 6.02e-01 0.06400 0.004180 0.063900 9.39e-01 2.40e-01
Methylation 10 4.98e-01 6.02e-01 0.22100 -0.048600 -0.215000 7.90e-01 2.38e-01
Synthesis of IP2, IP, and Ins in the cytosol 12 4.99e-01 6.02e-01 0.18900 -0.033100 0.186000 8.43e-01 2.66e-01
Signaling by FGFR3 fusions in cancer 10 5.05e-01 6.09e-01 0.22900 0.192000 0.124000 2.93e-01 4.96e-01
Hedgehog 'off' state 87 5.06e-01 6.09e-01 0.07490 0.020000 0.072100 7.47e-01 2.46e-01
Metabolic disorders of biological oxidation enzymes 13 5.06e-01 6.09e-01 0.18100 -0.180000 0.020600 2.62e-01 8.98e-01
Gap junction trafficking 11 5.06e-01 6.09e-01 0.21400 0.089000 0.195000 6.09e-01 2.63e-01
Signaling by FGFR in disease 47 5.08e-01 6.11e-01 0.10600 0.078800 0.070900 3.50e-01 4.01e-01
Mismatch Repair 14 5.09e-01 6.11e-01 0.17200 0.169000 -0.031200 2.74e-01 8.40e-01
RHO GTPases Activate NADPH Oxidases 13 5.12e-01 6.14e-01 0.17400 -0.059500 0.163000 7.10e-01 3.09e-01
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 16 5.12e-01 6.14e-01 0.17100 0.040600 0.167000 7.79e-01 2.49e-01
PINK1-PRKN Mediated Mitophagy 17 5.15e-01 6.16e-01 0.14900 0.133000 -0.068000 3.42e-01 6.28e-01
VLDLR internalisation and degradation 11 5.15e-01 6.16e-01 0.18600 -0.170000 0.077100 3.30e-01 6.58e-01
Insulin receptor recycling 17 5.18e-01 6.19e-01 0.16200 0.018100 0.161000 8.97e-01 2.52e-01
FOXO-mediated transcription of cell cycle genes 16 5.19e-01 6.19e-01 0.16300 -0.163000 -0.000376 2.58e-01 9.98e-01
Signaling by NTRK3 (TRKC) 16 5.22e-01 6.23e-01 0.15800 -0.155000 0.027600 2.82e-01 8.49e-01
Signaling by FGFR4 29 5.27e-01 6.28e-01 0.12600 0.040300 0.120000 7.07e-01 2.65e-01
Budding and maturation of HIV virion 22 5.28e-01 6.29e-01 0.14500 0.047300 0.137000 7.01e-01 2.66e-01
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 14 5.29e-01 6.29e-01 0.18100 0.172000 0.054300 2.65e-01 7.25e-01
FRS-mediated FGFR3 signaling 12 5.31e-01 6.31e-01 0.19800 0.085500 0.179000 6.08e-01 2.83e-01
RMTs methylate histone arginines 28 5.34e-01 6.33e-01 0.11400 -0.103000 0.048100 3.46e-01 6.59e-01
Oncogene Induced Senescence 29 5.35e-01 6.34e-01 0.12700 0.113000 0.058800 2.92e-01 5.84e-01
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling 20 5.37e-01 6.36e-01 0.15600 -0.104000 -0.116000 4.22e-01 3.69e-01
Class I MHC mediated antigen processing & presentation 303 5.46e-01 6.46e-01 0.04000 0.030800 0.025500 3.61e-01 4.48e-01
Signaling by NODAL 10 5.48e-01 6.47e-01 0.21600 -0.168000 -0.136000 3.58e-01 4.57e-01
Transcriptional Regulation by VENTX 34 5.48e-01 6.47e-01 0.09930 0.072400 -0.068000 4.65e-01 4.93e-01
Synthesis of PIPs at the plasma membrane 44 5.49e-01 6.48e-01 0.09670 0.095500 0.014900 2.73e-01 8.64e-01
CTLA4 inhibitory signaling 17 5.49e-01 6.48e-01 0.14700 -0.028100 0.144000 8.41e-01 3.04e-01
Glucose metabolism 69 5.56e-01 6.54e-01 0.07840 -0.023400 -0.074800 7.38e-01 2.84e-01
Acyl chain remodelling of PE 11 5.57e-01 6.55e-01 0.18100 0.179000 -0.028000 3.04e-01 8.72e-01
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism 10 5.59e-01 6.55e-01 0.20000 -0.197000 -0.034100 2.80e-01 8.52e-01
alpha-linolenic acid (ALA) metabolism 10 5.59e-01 6.55e-01 0.20000 -0.197000 -0.034100 2.80e-01 8.52e-01
NOTCH1 Intracellular Domain Regulates Transcription 42 5.59e-01 6.55e-01 0.08880 -0.042800 0.077800 6.31e-01 3.83e-01
DAP12 interactions 15 5.60e-01 6.55e-01 0.16300 0.026200 0.161000 8.60e-01 2.81e-01
DAP12 signaling 15 5.60e-01 6.55e-01 0.16300 0.026200 0.161000 8.60e-01 2.81e-01
FRS-mediated FGFR2 signaling 12 5.68e-01 6.65e-01 0.16600 -0.058600 0.155000 7.25e-01 3.52e-01
Resolution of D-Loop Structures 21 5.72e-01 6.67e-01 0.14300 0.118000 0.081300 3.50e-01 5.19e-01
Resolution of D-loop Structures through Holliday Junction Intermediates 21 5.72e-01 6.67e-01 0.14300 0.118000 0.081300 3.50e-01 5.19e-01
Purine catabolism 14 5.74e-01 6.69e-01 0.17600 -0.119000 -0.130000 4.42e-01 4.02e-01
Synthesis of active ubiquitin: roles of E1 and E2 enzymes 25 5.75e-01 6.69e-01 0.12900 0.114000 0.062100 3.26e-01 5.91e-01
Dopamine Neurotransmitter Release Cycle 11 5.75e-01 6.69e-01 0.17800 -0.015100 0.178000 9.31e-01 3.08e-01
Endosomal Sorting Complex Required For Transport (ESCRT) 24 5.80e-01 6.74e-01 0.13300 0.080700 0.105000 4.94e-01 3.72e-01
Hyaluronan metabolism 11 5.81e-01 6.75e-01 0.16800 -0.072400 0.152000 6.78e-01 3.83e-01
Signal amplification 20 5.89e-01 6.84e-01 0.14000 0.058800 0.127000 6.49e-01 3.24e-01
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 27 5.91e-01 6.86e-01 0.12200 -0.100000 -0.070000 3.66e-01 5.30e-01
Signaling by ERBB2 TMD/JMD mutants 14 5.94e-01 6.88e-01 0.14400 -0.106000 0.096800 4.91e-01 5.31e-01
DCC mediated attractive signaling 13 5.95e-01 6.89e-01 0.15800 -0.157000 0.018300 3.28e-01 9.09e-01
Signaling by FGFR1 in disease 30 5.96e-01 6.89e-01 0.10400 0.012000 -0.103000 9.09e-01 3.28e-01
Activation of the AP-1 family of transcription factors 10 5.96e-01 6.89e-01 0.18200 -0.007420 0.182000 9.68e-01 3.19e-01
SARS-CoV-1 Infection 40 5.97e-01 6.90e-01 0.08810 -0.022000 0.085300 8.10e-01 3.51e-01
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 13 6.00e-01 6.92e-01 0.14800 0.112000 -0.096400 4.84e-01 5.47e-01
Interleukin-7 signaling 12 6.01e-01 6.92e-01 0.17300 -0.168000 -0.042700 3.15e-01 7.98e-01
Endogenous sterols 13 6.01e-01 6.92e-01 0.16800 -0.054300 -0.159000 7.35e-01 3.21e-01
MAP3K8 (TPL2)-dependent MAPK1/3 activation 13 6.02e-01 6.92e-01 0.15900 -0.002050 0.159000 9.90e-01 3.21e-01
mRNA decay by 5' to 3' exoribonuclease 14 6.03e-01 6.92e-01 0.14700 0.143000 -0.035900 3.55e-01 8.16e-01
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects 16 6.03e-01 6.92e-01 0.14100 -0.013800 0.140000 9.24e-01 3.32e-01
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) 16 6.03e-01 6.92e-01 0.14100 -0.013800 0.140000 9.24e-01 3.32e-01
Growth hormone receptor signaling 17 6.05e-01 6.93e-01 0.12800 -0.083600 0.097300 5.51e-01 4.87e-01
Signaling by KIT in disease 17 6.06e-01 6.93e-01 0.13900 -0.139000 -0.004910 3.21e-01 9.72e-01
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants 17 6.06e-01 6.93e-01 0.13900 -0.139000 -0.004910 3.21e-01 9.72e-01
Synthesis of glycosylphosphatidylinositol (GPI) 15 6.06e-01 6.93e-01 0.14000 0.131000 -0.048500 3.80e-01 7.45e-01
Gamma carboxylation, hypusine formation and arylsulfatase activation 28 6.09e-01 6.96e-01 0.11700 -0.084100 -0.082100 4.42e-01 4.53e-01
Synthesis of PC 21 6.10e-01 6.96e-01 0.13500 -0.095500 -0.096100 4.49e-01 4.46e-01
Tie2 Signaling 13 6.13e-01 6.99e-01 0.16200 0.158000 0.036400 3.24e-01 8.20e-01
NOD1/2 Signaling Pathway 27 6.19e-01 7.04e-01 0.10300 -0.097900 0.030900 3.79e-01 7.81e-01
Regulation of FZD by ubiquitination 11 6.20e-01 7.05e-01 0.15600 -0.101000 0.118000 5.61e-01 4.98e-01
Depolymerisation of the Nuclear Lamina 13 6.23e-01 7.08e-01 0.16700 0.091300 0.140000 5.69e-01 3.82e-01
MECP2 regulates neuronal receptors and channels 10 6.25e-01 7.10e-01 0.19000 0.154000 0.113000 4.01e-01 5.37e-01
ERKs are inactivated 13 6.32e-01 7.17e-01 0.14100 -0.081400 0.115000 6.12e-01 4.74e-01
Downregulation of ERBB2 signaling 18 6.33e-01 7.17e-01 0.12400 -0.027100 0.121000 8.43e-01 3.74e-01
Mitochondrial iron-sulfur cluster biogenesis 12 6.33e-01 7.17e-01 0.16900 -0.074800 -0.151000 6.54e-01 3.64e-01
Activated NTRK2 signals through FRS2 and FRS3 10 6.34e-01 7.17e-01 0.18000 0.047400 0.174000 7.95e-01 3.42e-01
Cytochrome c-mediated apoptotic response 10 6.35e-01 7.17e-01 0.17000 -0.010300 0.170000 9.55e-01 3.53e-01
Glycogen synthesis 12 6.36e-01 7.18e-01 0.15000 -0.144000 0.040700 3.87e-01 8.07e-01
Adrenaline,noradrenaline inhibits insulin secretion 17 6.36e-01 7.18e-01 0.14300 -0.082900 -0.117000 5.54e-01 4.05e-01
Aberrant regulation of mitotic exit in cancer due to RB1 defects 20 6.38e-01 7.20e-01 0.12100 0.121000 -0.000141 3.50e-01 9.99e-01
Glutamate Neurotransmitter Release Cycle 12 6.39e-01 7.20e-01 0.15100 -0.024800 0.149000 8.82e-01 3.70e-01
Pre-NOTCH Transcription and Translation 31 6.41e-01 7.21e-01 0.10200 0.034000 0.096200 7.43e-01 3.54e-01
Iron uptake and transport 43 6.45e-01 7.25e-01 0.07540 -0.049400 0.057100 5.76e-01 5.18e-01
CD28 co-stimulation 25 6.49e-01 7.29e-01 0.09830 -0.060300 0.077600 6.02e-01 5.02e-01
G beta:gamma signalling through PLC beta 12 6.51e-01 7.30e-01 0.16700 -0.119000 -0.117000 4.75e-01 4.83e-01
Presynaptic function of Kainate receptors 12 6.51e-01 7.30e-01 0.16700 -0.119000 -0.117000 4.75e-01 4.83e-01
Fatty acyl-CoA biosynthesis 18 6.59e-01 7.38e-01 0.11400 -0.062100 0.095900 6.49e-01 4.81e-01
Signaling by cytosolic FGFR1 fusion mutants 17 6.59e-01 7.38e-01 0.12700 -0.003780 -0.127000 9.79e-01 3.66e-01
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 12 6.62e-01 7.40e-01 0.15500 0.031400 0.151000 8.50e-01 3.64e-01
PI-3K cascade:FGFR2 10 6.67e-01 7.45e-01 0.15000 -0.108000 0.104000 5.56e-01 5.67e-01
HDACs deacetylate histones 30 6.69e-01 7.46e-01 0.09450 0.094300 0.006880 3.72e-01 9.48e-01
STING mediated induction of host immune responses 11 6.71e-01 7.48e-01 0.15000 0.149000 -0.020100 3.93e-01 9.08e-01
TP53 Regulates Transcription of Death Receptors and Ligands 11 6.71e-01 7.48e-01 0.15200 -0.008090 0.152000 9.63e-01 3.84e-01
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 36 6.75e-01 7.51e-01 0.09220 0.060100 0.069900 5.33e-01 4.68e-01
FOXO-mediated transcription of cell death genes 14 6.76e-01 7.51e-01 0.14500 -0.128000 -0.068100 4.06e-01 6.59e-01
Aberrant regulation of mitotic cell cycle due to RB1 defects 35 6.77e-01 7.51e-01 0.09300 0.074300 0.056000 4.47e-01 5.67e-01
Diseases of mitotic cell cycle 35 6.77e-01 7.51e-01 0.09300 0.074300 0.056000 4.47e-01 5.67e-01
Gap junction trafficking and regulation 13 6.77e-01 7.51e-01 0.14500 0.033400 0.141000 8.35e-01 3.79e-01
Regulated proteolysis of p75NTR 11 6.83e-01 7.56e-01 0.15900 0.058300 0.148000 7.38e-01 3.95e-01
Disorders of Developmental Biology 10 6.85e-01 7.56e-01 0.16300 -0.041200 -0.158000 8.21e-01 3.87e-01
Disorders of Nervous System Development 10 6.85e-01 7.56e-01 0.16300 -0.041200 -0.158000 8.21e-01 3.87e-01
Loss of function of MECP2 in Rett syndrome 10 6.85e-01 7.56e-01 0.16300 -0.041200 -0.158000 8.21e-01 3.87e-01
Pervasive developmental disorders 10 6.85e-01 7.56e-01 0.16300 -0.041200 -0.158000 8.21e-01 3.87e-01
SUMOylation of DNA methylation proteins 15 6.85e-01 7.56e-01 0.14000 0.105000 0.093200 4.83e-01 5.32e-01
VxPx cargo-targeting to cilium 17 6.92e-01 7.62e-01 0.12500 -0.041500 -0.118000 7.67e-01 3.99e-01
Formation of Fibrin Clot (Clotting Cascade) 13 6.92e-01 7.62e-01 0.14600 0.073300 0.127000 6.47e-01 4.29e-01
Aggrephagy 16 6.93e-01 7.63e-01 0.12900 0.046900 0.121000 7.45e-01 4.04e-01
Inactivation, recovery and regulation of the phototransduction cascade 13 7.03e-01 7.72e-01 0.12300 -0.102000 0.069900 5.26e-01 6.63e-01
The phototransduction cascade 13 7.03e-01 7.72e-01 0.12300 -0.102000 0.069900 5.26e-01 6.63e-01
Regulation of localization of FOXO transcription factors 11 7.06e-01 7.72e-01 0.15300 -0.140000 -0.063100 4.23e-01 7.17e-01
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 50 7.07e-01 7.72e-01 0.06820 -0.067900 -0.005550 4.07e-01 9.46e-01
Constitutive Signaling by NOTCH1 PEST Domain Mutants 50 7.07e-01 7.72e-01 0.06820 -0.067900 -0.005550 4.07e-01 9.46e-01
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer 50 7.07e-01 7.72e-01 0.06820 -0.067900 -0.005550 4.07e-01 9.46e-01
Signaling by NOTCH1 PEST Domain Mutants in Cancer 50 7.07e-01 7.72e-01 0.06820 -0.067900 -0.005550 4.07e-01 9.46e-01
Signaling by NOTCH1 in Cancer 50 7.07e-01 7.72e-01 0.06820 -0.067900 -0.005550 4.07e-01 9.46e-01
ABC-family proteins mediated transport 76 7.09e-01 7.73e-01 0.05240 0.050800 -0.012600 4.44e-01 8.50e-01
Downstream signaling of activated FGFR3 17 7.11e-01 7.75e-01 0.12500 0.092900 0.083700 5.07e-01 5.50e-01
Signaling by NOTCH1 63 7.20e-01 7.84e-01 0.05430 -0.044900 0.030400 5.38e-01 6.77e-01
SHC-mediated cascade:FGFR4 10 7.22e-01 7.86e-01 0.13500 -0.089000 0.101000 6.26e-01 5.81e-01
RUNX3 regulates NOTCH signaling 13 7.31e-01 7.95e-01 0.13600 0.080200 0.110000 6.17e-01 4.92e-01
CD209 (DC-SIGN) signaling 17 7.33e-01 7.96e-01 0.10200 -0.048700 0.089600 7.28e-01 5.22e-01
Tight junction interactions 11 7.35e-01 7.97e-01 0.14600 0.071900 0.127000 6.80e-01 4.67e-01
Signaling by BMP 23 7.40e-01 8.02e-01 0.08590 -0.046600 0.072200 6.99e-01 5.49e-01
Estrogen-dependent nuclear events downstream of ESR-membrane signaling 19 7.42e-01 8.04e-01 0.10600 -0.101000 -0.030600 4.44e-01 8.17e-01
Signaling by ERBB2 in Cancer 18 7.43e-01 8.04e-01 0.10200 -0.012200 0.101000 9.28e-01 4.59e-01
Glucagon-type ligand receptors 11 7.44e-01 8.04e-01 0.14500 -0.096200 -0.108000 5.81e-01 5.35e-01
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 17 7.44e-01 8.04e-01 0.11600 0.076200 0.087800 5.86e-01 5.31e-01
Signaling by Ligand-Responsive EGFR Variants in Cancer 17 7.44e-01 8.04e-01 0.11600 0.076200 0.087800 5.86e-01 5.31e-01
PI-3K cascade:FGFR3 10 7.45e-01 8.04e-01 0.14800 0.065300 0.133000 7.21e-01 4.66e-01
Glutathione synthesis and recycling 10 7.47e-01 8.05e-01 0.12900 -0.061800 0.113000 7.35e-01 5.36e-01
Regulation of RUNX1 Expression and Activity 17 7.48e-01 8.05e-01 0.09770 0.063400 -0.074300 6.51e-01 5.96e-01
NRIF signals cell death from the nucleus 13 7.50e-01 8.07e-01 0.13000 0.075400 0.106000 6.38e-01 5.06e-01
Regulation of beta-cell development 17 7.53e-01 8.09e-01 0.09780 -0.087000 0.044500 5.35e-01 7.51e-01
Insulin processing 19 7.61e-01 8.17e-01 0.09310 0.090200 -0.022800 4.96e-01 8.63e-01
Acyl chain remodelling of PC 12 7.62e-01 8.18e-01 0.11600 0.111000 -0.032700 5.05e-01 8.44e-01
TRAF3-dependent IRF activation pathway 12 7.64e-01 8.20e-01 0.11600 -0.114000 0.025200 4.95e-01 8.80e-01
NOTCH4 Intracellular Domain Regulates Transcription 15 7.66e-01 8.21e-01 0.10800 0.001610 0.108000 9.91e-01 4.71e-01
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 13 7.69e-01 8.23e-01 0.11800 0.116000 0.021300 4.69e-01 8.94e-01
Kinesins 24 7.71e-01 8.24e-01 0.08030 0.077000 -0.022900 5.14e-01 8.46e-01
Deactivation of the beta-catenin transactivating complex 32 7.85e-01 8.38e-01 0.06500 -0.044900 0.046900 6.60e-01 6.46e-01
Protein methylation 10 7.90e-01 8.44e-01 0.12300 -0.004400 0.123000 9.81e-01 5.02e-01
TP53 Regulates Transcription of Cell Death Genes 34 7.92e-01 8.45e-01 0.06750 -0.067400 -0.004220 4.97e-01 9.66e-01
Downstream signaling of activated FGFR1 19 7.93e-01 8.45e-01 0.09470 0.035200 0.087900 7.91e-01 5.07e-01
G-protein beta:gamma signalling 20 7.95e-01 8.47e-01 0.09410 -0.076400 -0.054800 5.54e-01 6.71e-01
Signaling by Erythropoietin 19 7.97e-01 8.47e-01 0.08640 -0.085800 0.010200 5.17e-01 9.39e-01
Regulation of TP53 Activity through Association with Co-factors 12 7.97e-01 8.47e-01 0.11400 0.017600 0.112000 9.16e-01 5.01e-01
Extra-nuclear estrogen signaling 53 7.98e-01 8.47e-01 0.05770 0.041600 0.040000 6.01e-01 6.15e-01
COPI-mediated anterograde transport 73 8.01e-01 8.50e-01 0.04850 0.027800 0.039800 6.82e-01 5.57e-01
Post-translational modification: synthesis of GPI-anchored proteins 36 8.02e-01 8.50e-01 0.06090 0.013500 -0.059400 8.89e-01 5.38e-01
FGFR1 mutant receptor activation 23 8.03e-01 8.50e-01 0.07950 -0.003790 -0.079400 9.75e-01 5.10e-01
Diseases associated with glycosylation precursor biosynthesis 18 8.03e-01 8.50e-01 0.09450 0.035100 0.087700 7.96e-01 5.20e-01
Cytosolic sulfonation of small molecules 11 8.15e-01 8.62e-01 0.10500 0.029400 -0.101000 8.66e-01 5.62e-01
Signaling by ERBB2 KD Mutants 17 8.22e-01 8.69e-01 0.08020 -0.062100 0.050700 6.58e-01 7.17e-01
WNT ligand biogenesis and trafficking 12 8.25e-01 8.70e-01 0.10600 -0.103000 -0.025900 5.37e-01 8.77e-01
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 31 8.26e-01 8.70e-01 0.06760 0.026200 0.062300 8.01e-01 5.49e-01
G beta:gamma signalling through BTK 10 8.26e-01 8.70e-01 0.12000 -0.052000 -0.108000 7.76e-01 5.56e-01
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 14 8.35e-01 8.79e-01 0.09870 0.047600 0.086500 7.58e-01 5.75e-01
Signaling by FGFR4 in disease 11 8.42e-01 8.86e-01 0.10800 -0.042900 -0.098700 8.06e-01 5.71e-01
Signaling by NTRK2 (TRKB) 21 8.45e-01 8.87e-01 0.07380 0.009540 0.073200 9.40e-01 5.62e-01
Nuclear signaling by ERBB4 20 8.45e-01 8.87e-01 0.07300 -0.072800 0.005550 5.73e-01 9.66e-01
SHC-mediated cascade:FGFR1 10 8.45e-01 8.87e-01 0.10200 -0.017400 0.100000 9.24e-01 5.84e-01
PI-3K cascade:FGFR4 10 8.46e-01 8.87e-01 0.10500 -0.105000 -0.007870 5.65e-01 9.66e-01
RA biosynthesis pathway 11 8.48e-01 8.88e-01 0.09140 -0.068000 0.061000 6.96e-01 7.26e-01
Prostacyclin signalling through prostacyclin receptor 12 8.48e-01 8.88e-01 0.10200 -0.089200 -0.049000 5.93e-01 7.69e-01
G beta:gamma signalling through CDC42 13 8.50e-01 8.89e-01 0.09270 -0.016200 -0.091300 9.20e-01 5.69e-01
NOTCH3 Intracellular Domain Regulates Transcription 18 8.52e-01 8.89e-01 0.07050 -0.045600 0.053800 7.38e-01 6.93e-01
Insulin receptor signalling cascade 32 8.52e-01 8.89e-01 0.06230 0.037300 0.049900 7.15e-01 6.25e-01
FRS-mediated FGFR4 signaling 12 8.60e-01 8.97e-01 0.08360 -0.056500 0.061500 7.35e-01 7.12e-01
Transferrin endocytosis and recycling 21 8.62e-01 8.99e-01 0.07390 0.044400 0.059100 7.25e-01 6.40e-01
Synthesis of very long-chain fatty acyl-CoAs 10 8.65e-01 9.01e-01 0.09760 0.002870 0.097500 9.87e-01 5.93e-01
Signaling by WNT in cancer 28 8.69e-01 9.04e-01 0.05280 0.036300 -0.038300 7.40e-01 7.26e-01
RAF activation 34 8.69e-01 9.04e-01 0.05450 -0.016700 -0.051900 8.66e-01 6.01e-01
RAB GEFs exchange GTP for GDP on RABs 81 8.70e-01 9.04e-01 0.03510 0.033700 0.009820 6.01e-01 8.79e-01
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 16 8.72e-01 9.05e-01 0.07870 -0.074700 -0.024800 6.05e-01 8.64e-01
Antigen processing: Ubiquitination & Proteasome degradation 265 8.74e-01 9.05e-01 0.01790 0.017600 -0.003080 6.24e-01 9.32e-01
Rab regulation of trafficking 110 8.74e-01 9.05e-01 0.03100 0.020500 0.023200 7.11e-01 6.75e-01
Gastrin-CREB signalling pathway via PKC and MAPK 15 8.75e-01 9.05e-01 0.07610 -0.000157 0.076100 9.99e-01 6.10e-01
Downstream signaling of activated FGFR2 17 8.83e-01 9.13e-01 0.06750 -0.008850 0.066900 9.50e-01 6.33e-01
Nicotinamide salvaging 12 8.90e-01 9.20e-01 0.08640 -0.069900 -0.050800 6.75e-01 7.60e-01
Maturation of nucleoprotein 10 8.93e-01 9.21e-01 0.08480 -0.005810 0.084600 9.75e-01 6.43e-01
Peptide hormone metabolism 39 8.93e-01 9.21e-01 0.04530 0.011200 0.043900 9.04e-01 6.36e-01
G beta:gamma signalling through PI3Kgamma 15 8.94e-01 9.22e-01 0.07590 -0.062000 -0.043900 6.78e-01 7.69e-01
TRAF6 mediated IRF7 activation 14 9.01e-01 9.28e-01 0.07510 0.036700 0.065500 8.12e-01 6.72e-01
Signaling by ERBB2 ECD mutants 15 9.08e-01 9.34e-01 0.06080 -0.055300 0.025200 7.11e-01 8.66e-01
Signaling by NOTCH2 24 9.08e-01 9.34e-01 0.05500 -0.026100 -0.048400 8.25e-01 6.82e-01
Activated NOTCH1 Transmits Signal to the Nucleus 24 9.10e-01 9.34e-01 0.05160 -0.051300 -0.005360 6.64e-01 9.64e-01
IGF1R signaling cascade 30 9.10e-01 9.34e-01 0.04910 0.027800 0.040500 7.92e-01 7.02e-01
Cleavage of the damaged purine 10 9.12e-01 9.34e-01 0.08280 0.075700 0.033600 6.79e-01 8.54e-01
Depurination 10 9.12e-01 9.34e-01 0.08280 0.075700 0.033600 6.79e-01 8.54e-01
Recognition and association of DNA glycosylase with site containing an affected purine 10 9.12e-01 9.34e-01 0.08280 0.075700 0.033600 6.79e-01 8.54e-01
RUNX2 regulates osteoblast differentiation 20 9.16e-01 9.36e-01 0.05860 -0.041200 -0.041800 7.50e-01 7.47e-01
CD28 dependent PI3K/Akt signaling 17 9.16e-01 9.36e-01 0.05640 -0.055600 0.009720 6.92e-01 9.45e-01
FCERI mediated MAPK activation 23 9.17e-01 9.36e-01 0.04870 -0.005820 0.048300 9.61e-01 6.89e-01
Neddylation 200 9.19e-01 9.38e-01 0.01760 -0.005470 -0.016800 8.94e-01 6.84e-01
Thromboxane signalling through TP receptor 14 9.22e-01 9.41e-01 0.06660 0.055100 0.037400 7.21e-01 8.09e-01
FRS-mediated FGFR1 signaling 12 9.35e-01 9.50e-01 0.06090 0.003190 0.060800 9.85e-01 7.15e-01
Cleavage of the damaged pyrimidine 14 9.35e-01 9.50e-01 0.05990 0.053600 0.026900 7.29e-01 8.62e-01
Depyrimidination 14 9.35e-01 9.50e-01 0.05990 0.053600 0.026900 7.29e-01 8.62e-01
Recognition and association of DNA glycosylase with site containing an affected pyrimidine 14 9.35e-01 9.50e-01 0.05990 0.053600 0.026900 7.29e-01 8.62e-01
Signaling by FGFR3 in disease 14 9.36e-01 9.50e-01 0.06010 0.049600 0.033800 7.48e-01 8.27e-01
Signaling by FGFR3 point mutants in cancer 14 9.36e-01 9.50e-01 0.06010 0.049600 0.033800 7.48e-01 8.27e-01
IRS-mediated signalling 27 9.41e-01 9.54e-01 0.04210 0.031000 0.028500 7.81e-01 7.98e-01
mTORC1-mediated signalling 23 9.44e-01 9.57e-01 0.04350 -0.021700 -0.037700 8.57e-01 7.55e-01
Regulation of Complement cascade 13 9.51e-01 9.62e-01 0.04860 0.047700 -0.009510 7.66e-01 9.53e-01
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 19 9.51e-01 9.62e-01 0.04060 -0.005170 0.040300 9.69e-01 7.61e-01
ADP signalling through P2Y purinoceptor 12 13 9.52e-01 9.62e-01 0.05260 0.048300 0.020900 7.63e-01 8.96e-01
G-protein activation 13 9.52e-01 9.62e-01 0.05260 0.048300 0.020900 7.63e-01 8.96e-01
PI3K Cascade 23 9.54e-01 9.63e-01 0.03880 0.015100 0.035800 9.01e-01 7.67e-01
ADP signalling through P2Y purinoceptor 1 15 9.55e-01 9.63e-01 0.04180 -0.036500 0.020500 8.07e-01 8.91e-01
Signaling by ERBB4 37 9.62e-01 9.69e-01 0.02460 0.010700 -0.022100 9.10e-01 8.16e-01
Constitutive Signaling by EGFRvIII 15 9.68e-01 9.74e-01 0.04030 0.035500 0.019100 8.12e-01 8.98e-01
Signaling by EGFRvIII in Cancer 15 9.68e-01 9.74e-01 0.04030 0.035500 0.019100 8.12e-01 8.98e-01
Base-Excision Repair, AP Site Formation 16 9.77e-01 9.81e-01 0.03090 0.030900 -0.000317 8.31e-01 9.98e-01
RUNX2 regulates bone development 26 9.79e-01 9.83e-01 0.02140 -0.019000 0.009850 8.67e-01 9.31e-01
Complement cascade 14 9.82e-01 9.85e-01 0.03070 -0.008390 -0.029500 9.57e-01 8.48e-01
PI-3K cascade:FGFR1 10 9.83e-01 9.86e-01 0.03460 -0.033500 -0.008760 8.54e-01 9.62e-01
IRS-related events triggered by IGF1R 29 9.86e-01 9.87e-01 0.01820 0.000983 0.018100 9.93e-01 8.66e-01
COPI-independent Golgi-to-ER retrograde traffic 27 9.94e-01 9.94e-01 0.01340 0.011800 0.006230 9.15e-01 9.55e-01
Downstream signaling of activated FGFR4 17 9.99e-01 9.99e-01 0.00742 -0.007380 0.000769 9.58e-01 9.96e-01


Detailed Gene set reports


Metabolism of RNA

Metabolism of RNA
metric value
setSize 567
pMANOVA 1.18e-61
p.adjustMANOVA 1.46e-58
s.dist 0.445
s.human 0.37
s.mouse 0.247
p.human 2.72e-50
p.mouse 2.9e-23




Top 20 genes
Gene human mouse
ALYREF 5008 5231.0
HSPA1A 4887 5277.5
GTF2F1 4999 4919.0
CLP1 4787 5127.0
UTP14A 4777 5037.5
DDX21 4868 4778.0
HNRNPF 4978 4644.0
PDCD7 4447 5165.0
WBP11 4711 4773.0
SF3B4 4792 4649.0
NUP98 4235 5066.0
BUD31 4578 4660.0
NOP58 4891 4343.0
PRPF3 4719 4411.0
CDC40 4670 4455.0
KHSRP 4775 4318.0
GTF2F2 4067 5069.0
DCAF13 4800 4163.0
GAR1 4132 4763.0
ETF1 3946 4969.0

Click HERE to show all gene set members

All member genes
human mouse
AAAS -3476 1550.0
ACTB 940 4977.0
ADAR -3014 420.0
ADARB1 -4854 -697.0
ADAT1 3686 -2144.0
ADAT2 -3238 -1317.0
ADAT3 3262 2891.0
AKT1 -4954 342.0
ALKBH8 1989 -4802.0
ALYREF 5008 5231.0
APOBEC2 -5343 -1989.0
AQR 3952 3898.0
BCAS2 4926 -2783.0
BMS1 3511 -4218.0
BUD31 4578 4660.0
BYSL 2701 1951.0
C1D 3347 -3256.0
C2orf49 3037 -3366.0
CASC3 9 1880.0
CCAR1 3856 -1363.0
CCNH 3825 -1657.0
CD2BP2 2749 -1010.0
CD44 837 4987.0
CDC40 4670 4455.0
CDC5L 2693 2309.0
CDK7 1571 -2032.0
CDKAL1 240 -1000.0
CHERP 4498 4178.0
CHTOP -574 2867.0
CLNS1A 155 632.0
CLP1 4787 5127.0
CNOT1 4456 -3764.0
CNOT10 1314 -2770.0
CNOT11 2698 -468.0
CNOT2 3263 1266.0
CNOT3 857 3443.0
CNOT4 2350 2040.0
CNOT6 1509 2491.0
CNOT6L -2201 -298.0
CNOT7 1298 -926.0
CNOT8 3240 -1672.0
CPSF1 -3670 1693.0
CPSF2 -922 1961.0
CPSF3 1953 -1.0
CPSF4 862 4036.0
CPSF7 407 2081.0
CRNKL1 4682 2187.0
CSNK1D -3539 3832.0
CSNK1E -5045 816.0
CSTF1 2216 2463.0
CSTF2 1437 -2189.0
CSTF2T 2703 4265.0
CSTF3 -2793 4044.0
CTNNBL1 -145 2378.0
CTU1 1091 1902.0
CTU2 -805 3378.0
CWC15 4989 -2691.0
CWC22 4974 3311.0
CWC27 1809 -3152.0
DCAF13 4800 4163.0
DCP1B -2739 -1269.0
DCP2 3899 -3761.0
DCPS -2174 3358.0
DDX1 3013 326.0
DDX20 4951 2067.0
DDX21 4868 4778.0
DDX23 -645 -3513.0
DDX39A 3417 2816.0
DDX39B 984 2712.0
DDX42 2929 4157.0
DDX46 2094 -1739.0
DDX47 3735 1436.0
DDX49 2178 4026.0
DDX5 4191 -2760.0
DDX6 3301 -2453.0
DHX15 2483 4240.0
DHX16 3981 306.0
DHX37 2105 2976.0
DHX38 2857 -865.0
DHX9 4151 322.0
DIEXF 4877 1147.0
DIMT1 2537 1451.0
DIS3 4973 1390.0
DKC1 3629 -171.0
DNAJC8 4247 1747.0
EBNA1BP2 4030 -1311.0
EDC3 599 -3045.0
EDC4 -3350 2170.0
EFTUD2 1157 3818.0
EIF4A1 2916 5133.0
EIF4A2 1360 1839.0
EIF4A3 4491 3824.0
EIF4B 993 -4215.0
EIF4E 2892 3735.0
EIF4G1 -2988 -4223.0
ELAC2 1520 1569.0
ELAVL1 2256 2925.0
ENPP2 3080 -3307.0
ERCC2 824 2393.0
ERCC3 473 1570.0
ERI1 2910 3935.0
ETF1 3946 4969.0
EXOSC1 1073 2615.0
EXOSC10 4991 893.0
EXOSC2 3309 3785.0
EXOSC3 3331 2172.0
EXOSC4 2447 -1601.0
EXOSC5 20 -1868.0
EXOSC7 -4980 510.0
EXOSC8 3102 2426.0
EXOSC9 4106 1068.0
FAM98B 3022 -860.0
FAU 2272 4115.0
FBL 4233 2213.0
FCF1 3303 2053.0
FIP1L1 3587 1848.0
FTSJ1 -980 -1260.0
FTSJ3 4444 3950.0
FUS 867 4337.0
FYTTD1 3374 4203.0
GAR1 4132 4763.0
GCFC2 4300 143.0
GEMIN2 3264 -1096.0
GEMIN5 4699 -3017.0
GEMIN6 3429 3153.0
GEMIN7 2344 2332.0
GEMIN8 94 982.0
GLE1 586 -4722.0
GNL3 4434 3817.0
GPKOW 590 2936.0
GSPT1 1495 -2535.0
GTF2F1 4999 4919.0
GTF2F2 4067 5069.0
GTF2H1 3886 1058.0
GTF2H2 4419 -2446.5
GTF2H3 -1925 467.0
GTF2H5 -878 -1711.0
GTPBP3 -946 -1509.0
HBS1L 2208 -2452.0
HEATR1 4911 3855.0
HNRNPA0 2412 4465.0
HNRNPA1 3878 3701.0
HNRNPA2B1 3693 -2053.0
HNRNPA3 2505 2697.0
HNRNPC 3406 2818.0
HNRNPD 4343 2983.0
HNRNPF 4978 4644.0
HNRNPH1 3339 4865.0
HNRNPH2 2261 730.0
HNRNPK 3054 2784.0
HNRNPL 1064 224.0
HNRNPM 4022 -3455.0
HNRNPR 4406 2984.0
HNRNPU 4229 4421.0
HNRNPUL1 2433 2224.0
HSD17B10 -1193 -485.0
HSPA1A 4887 5277.5
HSPA8 3674 5088.0
HSPB1 -4869 5277.5
IGF2 -4754 -3030.0
IGF2BP2 -3031 5173.0
IMP3 4536 -961.0
IMP4 2805 4315.0
ISG20L2 3385 4293.0
ISY1 2662 -1226.0
KHSRP 4775 4318.0
KRR1 3921 1112.0
LAGE3 -2536 -1908.0
LAS1L 3707 -281.0
LCMT2 3818 3987.0
LSM1 2752 2049.0
LSM10 -3826 1565.0
LSM11 -2895 465.0
LSM2 -1347 3340.0
LSM3 2210 355.0
LSM4 -2884 -589.0
LSM5 2324 358.0
LSM6 -1177 -1931.0
LSM7 -3487 916.0
LTV1 4806 3985.0
MAGOH 4561 4010.0
MAGOHB 2239 2185.0
MAPK11 -3385 -333.0
MAPK14 -1562 -1635.0
MAPKAPK2 -2489 -645.0
METTL1 1425 4090.0
METTL14 4358 -2575.0
METTL3 -3688 -545.0
MNAT1 830 -2433.0
MPHOSPH10 3928 2826.0
MPHOSPH6 2298 3067.0
MT-CO1 -3167 -4114.0
MT-CYB -1355 -2353.0
MT-ND1 -353 -2211.0
MT-ND2 -1120 -2087.0
MT-ND4 -2086 -1594.0
MT-ND5 -3244 -2323.0
MT-ND6 816 -4592.0
MTO1 3000 -3736.0
MYC 3994 4886.0
NAT10 3642 -1157.0
NCBP1 -1736 4182.0
NCBP2 4188 264.0
NCL 3573 3720.0
NDC1 1273 -2350.0
NHP2 694 2676.0
NIP7 3751 2512.0
NOB1 3229 3188.0
NOC4L 1763 2013.0
NOL11 4916 -392.0
NOL6 3819 2763.0
NOL9 4679 2138.0
NOP10 1336 911.0
NOP14 1590 4393.0
NOP2 3472 4824.0
NOP56 3099 3859.0
NOP58 4891 4343.0
NSUN2 3979 -348.0
NSUN4 -830 -5028.0
NSUN6 -148 -3775.0
NT5C3B -4265 3641.0
NUDT21 3626 3457.0
NUP107 3232 2949.0
NUP133 889 -4048.0
NUP153 4762 1533.0
NUP155 4306 -2233.0
NUP160 3998 1035.0
NUP188 2117 3830.0
NUP205 4438 3588.0
NUP214 3124 665.0
NUP35 4571 649.0
NUP37 -327 192.0
NUP43 4562 2216.0
NUP54 4508 3831.0
NUP85 3181 -393.0
NUP88 1244 2212.0
NUP93 -1503 3903.0
NUP98 4235 5066.0
NXF1 4992 -57.0
NXT1 1765 3801.0
OSGEP -3005 1333.0
PAIP1 4308 2613.0
PAN2 -4358 -2542.0
PAN3 -99 -1607.0
PARN 3874 -760.0
PATL1 3672 4524.0
PCBP1 -3158 3122.0
PCF11 -1597 -2897.0
PDCD11 -1465 815.0
PDCD7 4447 5165.0
PELP1 2605 1120.0
PES1 4214 3692.0
PHAX 4729 840.0
PHF5A 3478 1234.0
PLRG1 4237 138.0
PNO1 4623 332.0
PNRC2 2568 -4611.0
POLDIP3 -1320 4692.0
POLR2A 3861 5046.0
POLR2B 4509 -4119.0
POLR2C 4529 -904.0
POLR2D 1669 2692.0
POLR2E -667 1599.0
POLR2G 89 5112.0
POLR2H -3927 3497.0
POLR2I -154 81.0
POLR2K 2480 -1584.0
POLR2L -4314 4110.0
POP1 -89 1914.0
POP4 -1436 1917.0
POP5 3528 4019.0
POP7 386 1165.0
PPIE 2144 896.0
PPIH 594 369.0
PPIL1 863 1860.0
PPIL3 4044 -1466.0
PPIL4 3657 -214.0
PPP2CA 4482 3008.0
PPP2R1A -4013 -696.0
PPP2R2A 2264 3799.0
PPWD1 2992 -1498.0
PQBP1 -379 -1361.0
PRCC 2656 2793.0
PRKCA -2938 -2924.0
PRKCD -4276 3377.0
PRMT5 933 1373.0
PRPF19 2441 -4538.0
PRPF3 4719 4411.0
PRPF31 1339 4183.0
PRPF38A 4433 2282.0
PRPF4 3652 -2192.0
PRPF40A 4797 2652.0
PRPF6 684 2501.0
PRPF8 2926 -4269.0
PSMA1 2820 3328.0
PSMA3 3434 -4.0
PSMA4 769 958.0
PSMA6 2199 -1044.0
PSMA7 -2980 976.0
PSMB1 954 2628.0
PSMB10 -1800 2907.0
PSMB2 618 2471.0
PSMB4 -235 2096.0
PSMB5 -4113 -606.0
PSMB6 -793 914.0
PSMB7 -831 -1453.0
PSMB8 -675 2066.0
PSMB9 -1611 -2973.0
PSMC1 449 -336.0
PSMC2 -1311 3241.0
PSMC3 -2439 -369.0
PSMC4 2724 1416.0
PSMC5 1212 -1123.0
PSMC6 -2520 3423.0
PSMD1 2619 -1191.0
PSMD10 -1227 525.0
PSMD11 995 5183.0
PSMD12 3831 536.0
PSMD13 821 1665.0
PSMD14 -635 3816.0
PSMD2 -713 -555.0
PSMD3 -3343 2226.0
PSMD4 -214 2558.0
PSMD5 1807 3558.0
PSMD6 3537 -2207.0
PSMD7 -2329 1233.0
PSMD8 -3171 4626.0
PSMD9 4204 -970.0
PSME1 -2771 3350.0
PSME2 -4085 3584.0
PSME3 3333 3379.0
PSME4 1960 -4574.0
PSMF1 683 -1480.0
PTBP1 3063 4257.0
PUF60 -2093 2016.0
PUS1 1845 4083.0
PUS3 4566 796.0
PUS7 -584 283.0
PWP2 2462 745.0
QTRT1 -3825 1884.0
RAE1 4471 2389.0
RAN 2329 1938.0
RANBP2 4470 -3848.0
RBM17 2520 2504.0
RBM22 709 2550.0
RBM28 4327 107.0
RBM5 3930 1290.0
RCL1 3257 -48.0
RIOK1 3760 1972.0
RIOK3 -1480 -2083.0
RNGTT 4414 1057.0
RNMT 4864 -807.0
RNPC3 -3052 951.0
RNPS1 681 -379.0
RPL10 -3902 3841.0
RPL11 -2249 2690.0
RPL14 433 1505.0
RPL18 -1782 3926.0
RPL18A -2969 1546.0
RPL19 -502 2402.0
RPL22 1231 -695.0
RPL22L1 3380 4103.0
RPL23 -115 2472.0
RPL26 1047 3247.0
RPL28 -391 2871.0
RPL3 -786 4892.0
RPL30 286 2070.0
RPL31 -595 4273.0
RPL32 -367 2766.0
RPL34 1447 1856.0
RPL35A 812 1955.0
RPL36A 1261 2266.0
RPL37 -715 2388.0
RPL37A -1043 2280.0
RPL38 231 3306.0
RPL3L -5212 -3395.0
RPL4 -522 1026.0
RPL5 1206 4486.0
RPL7 1440 1916.0
RPL8 -2775 2474.0
RPLP2 -2469 2383.0
RPP14 2370 -3591.0
RPP30 2968 1226.0
RPP38 3980 247.0
RPP40 3369 -268.0
RPS11 -1582 3395.0
RPS12 -318 3958.0
RPS13 1131 3118.0
RPS14 -1412 1322.0
RPS15 -1799 1989.0
RPS15A -704 2410.0
RPS16 -1828 3864.0
RPS18 -974 2916.0
RPS19 -2045 2954.0
RPS20 -1844 4785.0
RPS21 -1536 707.0
RPS23 -68 1922.0
RPS24 256 1742.0
RPS26 -282 2982.0
RPS27A 783 1840.0
RPS27L -616 298.0
RPS29 -1140 2499.0
RPS3 -544 3102.0
RPS4X 83 1892.0
RPS5 -1577 2419.0
RPS6 -245 3549.0
RPS8 -1593 2271.0
RPS9 -1107 1580.0
RQCD1 4265 347.0
RRP1 1063 -1990.0
RRP36 1532 1854.0
RRP7A 2138 3626.0
RRP9 771 2325.0
RTCB 581 226.0
SARNP 569 48.0
SART1 759 2635.0
SEC13 730 1702.0
SEH1L 1085 4263.0
SENP3 2112 2465.0
SET 3683 2131.0
SF1 4412 3687.0
SF3A1 3470 1896.0
SF3A2 2302 3304.0
SF3A3 2871 2756.0
SF3B1 1067 3140.0
SF3B2 2676 -1599.0
SF3B3 3615 4529.0
SF3B4 4792 4649.0
SF3B5 1969 3781.0
SKIV2L 134 -1809.0
SLBP 2666 4952.0
SLU7 4893 3614.0
SMG1 3321 -2527.0
SMG5 -910 517.0
SMG6 258 141.0
SMG7 1383 259.0
SMG8 4625 1283.0
SMG9 -2328 2518.0
SMN1 4028 1732.5
SMNDC1 4537 3789.0
SNRNP200 2626 -3909.0
SNRNP25 2402 -2712.0
SNRNP27 2641 -1995.0
SNRNP35 -2744 -3140.0
SNRNP40 2967 3494.0
SNRNP48 4305 -939.0
SNRNP70 -267 -706.0
SNRPA1 4117 4600.0
SNRPB 3761 35.0
SNRPB2 4617 2625.0
SNRPC 3677 169.0
SNRPD1 3996 4006.0
SNRPD2 2043 -304.0
SNRPD3 2384 -1603.0
SNRPE 3421 760.0
SNRPF 3777 2400.0
SNRPG 3179 3615.0
SNRPN -2163 -2931.0
SNUPN 2836 588.0
SNW1 3618 4819.0
SRRM1 2285 -746.0
SRRM2 -1731 -3957.0
SRRT 4962 3050.0
SRSF1 1871 -429.0
SRSF11 3911 -4703.0
SRSF3 2586 3185.0
SRSF4 1929 4093.0
SRSF5 1997 -2886.0
SRSF6 1798 3296.0
SRSF7 3545 4305.0
SRSF9 3543 3246.0
SUGP1 -1552 1721.0
SUPT5H 1321 3508.0
SYF2 4472 2749.0
SYMPK -3207 -2811.0
TBL3 -1551 1063.0
TEX10 2840 -338.0
TFB1M 1537 -3367.0
TFIP11 5002 3365.0
TGS1 4576 2059.0
THADA 3513 -3025.0
THG1L 453 4258.0
THOC1 2868 2547.0
THOC2 4510 -4472.0
THOC3 2831 -1702.0
THOC5 4842 542.0
THOC6 -904 3700.0
THOC7 -873 -3339.0
THUMPD1 4666 -2564.0
TNKS1BP1 -4407 1783.0
TNPO1 3184 5129.0
TP53RK 3992 1448.0
TPR 2984 -1026.0
TPRKB 4453 288.0
TRA2B 4288 4466.0
TRDMT1 2027 -1277.0
TRIT1 2894 -494.0
TRMT1 2897 762.0
TRMT10A 1802 3940.0
TRMT10C 4780 -8.0
TRMT11 3034 1844.0
TRMT12 3365 2394.0
TRMT13 2904 -397.0
TRMT44 2292 1786.0
TRMT5 -517 4632.0
TRMT6 4499 1789.0
TRMT61A -2849 4213.0
TRMU 2385 -4283.0
TRNT1 3318 2516.0
TSEN15 3354 -453.0
TSEN2 -1816 -2245.0
TSEN34 3893 -877.0
TSEN54 -1614 2999.0
TSR1 3117 4777.0
TSR3 -3611 -3279.0
TTC37 1856 136.0
TXNL4A -698 1687.0
TYW1 2414 -335.0
TYW3 4142 -2073.0
TYW5 2090 541.0
U2AF2 4337 3060.0
U2SURP 4199 -2963.0
UBC 2672 4480.0
UPF1 2528 900.0
UPF2 3566 -3399.0
UPF3A -2545 842.0
UPF3B 1586 -4316.0
URM1 -1818 14.0
USP39 1526 2994.0
UTP14A 4777 5037.5
UTP14C 1565 5037.5
UTP15 4137 2775.0
UTP18 3851 3736.0
UTP20 4174 240.0
UTP3 4917 2928.0
UTP6 4779 -4513.0
WBP11 4711 4773.0
WBP4 3659 -1633.0
WBSCR22 1741 -1538.0
WDR12 1739 -3276.0
WDR18 -812 -1113.0
WDR3 4838 3546.0
WDR33 3143 1005.0
WDR36 4542 3505.0
WDR4 1093 503.0
WDR43 4883 3479.0
WDR46 3335 2646.0
WDR61 -1148 301.0
WDR75 3743 2374.0
WDR77 -799 1494.0
WTAP 4785 2089.0
XAB2 2348 1369.0
XPO1 990 1809.0
XPOT 705 680.0
XRN1 2636 -4002.0
XRN2 4296 1666.0
YBX1 -681 1282.0
YWHAB 3680 3415.0
YWHAZ 2019 4495.0
ZBTB8OS -54 2043.0
ZCCHC11 -2649 1194.0
ZCCHC6 3771 -1552.0
ZCRB1 833 -1382.0
ZFP36 -3486 4948.0
ZFP36L1 -4417 2339.0
ZMAT5 1059 360.0
ZRSR2 4437 -1079.0



Processing of Capped Intron-Containing Pre-mRNA

Processing of Capped Intron-Containing Pre-mRNA
metric value
setSize 212
pMANOVA 7.36e-40
p.adjustMANOVA 4.54e-37
s.dist 0.569
s.human 0.5
s.mouse 0.272
p.human 5.18e-36
p.mouse 9.76e-12




Top 20 genes
Gene human mouse
ALYREF 5008 5231
GTF2F1 4999 4919
CLP1 4787 5127
HNRNPF 4978 4644
PDCD7 4447 5165
WBP11 4711 4773
SF3B4 4792 4649
NUP98 4235 5066
BUD31 4578 4660
PRPF3 4719 4411
CDC40 4670 4455
GTF2F2 4067 5069
POLR2A 3861 5046
TRA2B 4288 4466
SNRPA1 4117 4600
CHERP 4498 4178
HNRNPU 4229 4421
HSPA8 3674 5088
MAGOH 4561 4010
SLU7 4893 3614

Click HERE to show all gene set members

All member genes
human mouse
AAAS -3476 1550
ALYREF 5008 5231
AQR 3952 3898
BCAS2 4926 -2783
BUD31 4578 4660
CASC3 9 1880
CCAR1 3856 -1363
CD2BP2 2749 -1010
CDC40 4670 4455
CDC5L 2693 2309
CHERP 4498 4178
CHTOP -574 2867
CLP1 4787 5127
CPSF1 -3670 1693
CPSF2 -922 1961
CPSF3 1953 -1
CPSF4 862 4036
CPSF7 407 2081
CRNKL1 4682 2187
CSTF1 2216 2463
CSTF2 1437 -2189
CSTF2T 2703 4265
CSTF3 -2793 4044
CTNNBL1 -145 2378
CWC15 4989 -2691
CWC22 4974 3311
CWC27 1809 -3152
DDX23 -645 -3513
DDX39A 3417 2816
DDX39B 984 2712
DDX42 2929 4157
DDX46 2094 -1739
DDX5 4191 -2760
DHX15 2483 4240
DHX16 3981 306
DHX38 2857 -865
DHX9 4151 322
DNAJC8 4247 1747
EFTUD2 1157 3818
EIF4A3 4491 3824
EIF4E 2892 3735
ELAVL1 2256 2925
FIP1L1 3587 1848
FUS 867 4337
FYTTD1 3374 4203
GCFC2 4300 143
GLE1 586 -4722
GPKOW 590 2936
GTF2F1 4999 4919
GTF2F2 4067 5069
HNRNPA0 2412 4465
HNRNPA1 3878 3701
HNRNPA2B1 3693 -2053
HNRNPA3 2505 2697
HNRNPC 3406 2818
HNRNPD 4343 2983
HNRNPF 4978 4644
HNRNPH1 3339 4865
HNRNPH2 2261 730
HNRNPK 3054 2784
HNRNPL 1064 224
HNRNPM 4022 -3455
HNRNPR 4406 2984
HNRNPU 4229 4421
HNRNPUL1 2433 2224
HSPA8 3674 5088
ISY1 2662 -1226
LSM2 -1347 3340
LSM3 2210 355
LSM4 -2884 -589
LSM5 2324 358
LSM6 -1177 -1931
LSM7 -3487 916
MAGOH 4561 4010
MAGOHB 2239 2185
METTL14 4358 -2575
METTL3 -3688 -545
NCBP1 -1736 4182
NCBP2 4188 264
NDC1 1273 -2350
NUDT21 3626 3457
NUP107 3232 2949
NUP133 889 -4048
NUP153 4762 1533
NUP155 4306 -2233
NUP160 3998 1035
NUP188 2117 3830
NUP205 4438 3588
NUP214 3124 665
NUP35 4571 649
NUP37 -327 192
NUP43 4562 2216
NUP54 4508 3831
NUP85 3181 -393
NUP88 1244 2212
NUP93 -1503 3903
NUP98 4235 5066
NXF1 4992 -57
NXT1 1765 3801
PCBP1 -3158 3122
PCF11 -1597 -2897
PDCD7 4447 5165
PHF5A 3478 1234
PLRG1 4237 138
POLDIP3 -1320 4692
POLR2A 3861 5046
POLR2B 4509 -4119
POLR2C 4529 -904
POLR2D 1669 2692
POLR2E -667 1599
POLR2G 89 5112
POLR2H -3927 3497
POLR2I -154 81
POLR2K 2480 -1584
POLR2L -4314 4110
PPIE 2144 896
PPIH 594 369
PPIL1 863 1860
PPIL3 4044 -1466
PPIL4 3657 -214
PPWD1 2992 -1498
PQBP1 -379 -1361
PRCC 2656 2793
PRPF19 2441 -4538
PRPF3 4719 4411
PRPF31 1339 4183
PRPF38A 4433 2282
PRPF4 3652 -2192
PRPF40A 4797 2652
PRPF6 684 2501
PRPF8 2926 -4269
PTBP1 3063 4257
PUF60 -2093 2016
RAE1 4471 2389
RANBP2 4470 -3848
RBM17 2520 2504
RBM22 709 2550
RBM5 3930 1290
RNPC3 -3052 951
RNPS1 681 -379
SARNP 569 48
SART1 759 2635
SEC13 730 1702
SEH1L 1085 4263
SF1 4412 3687
SF3A1 3470 1896
SF3A2 2302 3304
SF3A3 2871 2756
SF3B1 1067 3140
SF3B2 2676 -1599
SF3B3 3615 4529
SF3B4 4792 4649
SF3B5 1969 3781
SLBP 2666 4952
SLU7 4893 3614
SMNDC1 4537 3789
SNRNP200 2626 -3909
SNRNP25 2402 -2712
SNRNP27 2641 -1995
SNRNP35 -2744 -3140
SNRNP40 2967 3494
SNRNP48 4305 -939
SNRNP70 -267 -706
SNRPA1 4117 4600
SNRPB 3761 35
SNRPB2 4617 2625
SNRPC 3677 169
SNRPD1 3996 4006
SNRPD2 2043 -304
SNRPD3 2384 -1603
SNRPE 3421 760
SNRPF 3777 2400
SNRPG 3179 3615
SNRPN -2163 -2931
SNW1 3618 4819
SRRM1 2285 -746
SRRM2 -1731 -3957
SRRT 4962 3050
SRSF1 1871 -429
SRSF11 3911 -4703
SRSF3 2586 3185
SRSF4 1929 4093
SRSF5 1997 -2886
SRSF6 1798 3296
SRSF7 3545 4305
SRSF9 3543 3246
SUGP1 -1552 1721
SYF2 4472 2749
SYMPK -3207 -2811
TFIP11 5002 3365
THOC1 2868 2547
THOC2 4510 -4472
THOC3 2831 -1702
THOC5 4842 542
THOC6 -904 3700
THOC7 -873 -3339
TPR 2984 -1026
TRA2B 4288 4466
TXNL4A -698 1687
U2AF2 4337 3060
U2SURP 4199 -2963
UPF3B 1586 -4316
USP39 1526 2994
WBP11 4711 4773
WBP4 3659 -1633
WDR33 3143 1005
WTAP 4785 2089
XAB2 2348 1369
YBX1 -681 1282
ZCRB1 833 -1382
ZMAT5 1059 360
ZRSR2 4437 -1079



mRNA Splicing - Major Pathway

mRNA Splicing - Major Pathway
metric value
setSize 161
pMANOVA 1.6e-32
p.adjustMANOVA 5.11e-30
s.dist 0.59
s.human 0.508
s.mouse 0.3
p.human 1.02e-28
p.mouse 6.21e-11




Top 20 genes
Gene human mouse
ALYREF 5008 5231
GTF2F1 4999 4919
CLP1 4787 5127
HNRNPF 4978 4644
WBP11 4711 4773
SF3B4 4792 4649
BUD31 4578 4660
PRPF3 4719 4411
CDC40 4670 4455
GTF2F2 4067 5069
POLR2A 3861 5046
TRA2B 4288 4466
SNRPA1 4117 4600
CHERP 4498 4178
HNRNPU 4229 4421
HSPA8 3674 5088
MAGOH 4561 4010
SLU7 4893 3614
SNW1 3618 4819
SMNDC1 4537 3789

Click HERE to show all gene set members

All member genes
human mouse
ALYREF 5008 5231
AQR 3952 3898
BCAS2 4926 -2783
BUD31 4578 4660
CASC3 9 1880
CCAR1 3856 -1363
CD2BP2 2749 -1010
CDC40 4670 4455
CDC5L 2693 2309
CHERP 4498 4178
CLP1 4787 5127
CPSF1 -3670 1693
CPSF2 -922 1961
CPSF3 1953 -1
CPSF4 862 4036
CPSF7 407 2081
CRNKL1 4682 2187
CSTF1 2216 2463
CSTF2 1437 -2189
CSTF2T 2703 4265
CSTF3 -2793 4044
CTNNBL1 -145 2378
CWC15 4989 -2691
CWC22 4974 3311
CWC27 1809 -3152
DDX23 -645 -3513
DDX42 2929 4157
DDX46 2094 -1739
DDX5 4191 -2760
DHX15 2483 4240
DHX16 3981 306
DHX38 2857 -865
DHX9 4151 322
DNAJC8 4247 1747
EFTUD2 1157 3818
EIF4A3 4491 3824
ELAVL1 2256 2925
FIP1L1 3587 1848
FUS 867 4337
GCFC2 4300 143
GPKOW 590 2936
GTF2F1 4999 4919
GTF2F2 4067 5069
HNRNPA0 2412 4465
HNRNPA1 3878 3701
HNRNPA2B1 3693 -2053
HNRNPA3 2505 2697
HNRNPC 3406 2818
HNRNPD 4343 2983
HNRNPF 4978 4644
HNRNPH1 3339 4865
HNRNPH2 2261 730
HNRNPK 3054 2784
HNRNPL 1064 224
HNRNPM 4022 -3455
HNRNPR 4406 2984
HNRNPU 4229 4421
HNRNPUL1 2433 2224
HSPA8 3674 5088
ISY1 2662 -1226
LSM2 -1347 3340
LSM3 2210 355
LSM4 -2884 -589
LSM5 2324 358
LSM6 -1177 -1931
LSM7 -3487 916
MAGOH 4561 4010
MAGOHB 2239 2185
NCBP1 -1736 4182
NCBP2 4188 264
NUDT21 3626 3457
PCBP1 -3158 3122
PCF11 -1597 -2897
PHF5A 3478 1234
PLRG1 4237 138
POLR2A 3861 5046
POLR2B 4509 -4119
POLR2C 4529 -904
POLR2D 1669 2692
POLR2E -667 1599
POLR2G 89 5112
POLR2H -3927 3497
POLR2I -154 81
POLR2K 2480 -1584
POLR2L -4314 4110
PPIE 2144 896
PPIH 594 369
PPIL1 863 1860
PPIL3 4044 -1466
PPIL4 3657 -214
PPWD1 2992 -1498
PQBP1 -379 -1361
PRCC 2656 2793
PRPF19 2441 -4538
PRPF3 4719 4411
PRPF31 1339 4183
PRPF38A 4433 2282
PRPF4 3652 -2192
PRPF40A 4797 2652
PRPF6 684 2501
PRPF8 2926 -4269
PTBP1 3063 4257
PUF60 -2093 2016
RBM17 2520 2504
RBM22 709 2550
RBM5 3930 1290
RNPS1 681 -379
SART1 759 2635
SF1 4412 3687
SF3A1 3470 1896
SF3A2 2302 3304
SF3A3 2871 2756
SF3B1 1067 3140
SF3B2 2676 -1599
SF3B3 3615 4529
SF3B4 4792 4649
SF3B5 1969 3781
SLU7 4893 3614
SMNDC1 4537 3789
SNRNP200 2626 -3909
SNRNP27 2641 -1995
SNRNP40 2967 3494
SNRNP70 -267 -706
SNRPA1 4117 4600
SNRPB 3761 35
SNRPB2 4617 2625
SNRPC 3677 169
SNRPD1 3996 4006
SNRPD2 2043 -304
SNRPD3 2384 -1603
SNRPE 3421 760
SNRPF 3777 2400
SNRPG 3179 3615
SNRPN -2163 -2931
SNW1 3618 4819
SRRM1 2285 -746
SRRM2 -1731 -3957
SRRT 4962 3050
SRSF1 1871 -429
SRSF11 3911 -4703
SRSF3 2586 3185
SRSF4 1929 4093
SRSF5 1997 -2886
SRSF6 1798 3296
SRSF7 3545 4305
SRSF9 3543 3246
SUGP1 -1552 1721
SYF2 4472 2749
SYMPK -3207 -2811
TFIP11 5002 3365
TRA2B 4288 4466
TXNL4A -698 1687
U2AF2 4337 3060
U2SURP 4199 -2963
UPF3B 1586 -4316
USP39 1526 2994
WBP11 4711 4773
WBP4 3659 -1633
WDR33 3143 1005
XAB2 2348 1369
YBX1 -681 1282



mRNA Splicing

mRNA Splicing
metric value
setSize 169
pMANOVA 1.66e-32
p.adjustMANOVA 5.11e-30
s.dist 0.575
s.human 0.501
s.mouse 0.283
p.human 3.5e-29
p.mouse 2.56e-10




Top 20 genes
Gene human mouse
ALYREF 5008 5231
GTF2F1 4999 4919
CLP1 4787 5127
HNRNPF 4978 4644
PDCD7 4447 5165
WBP11 4711 4773
SF3B4 4792 4649
BUD31 4578 4660
PRPF3 4719 4411
CDC40 4670 4455
GTF2F2 4067 5069
POLR2A 3861 5046
TRA2B 4288 4466
SNRPA1 4117 4600
CHERP 4498 4178
HNRNPU 4229 4421
HSPA8 3674 5088
MAGOH 4561 4010
SLU7 4893 3614
SNW1 3618 4819

Click HERE to show all gene set members

All member genes
human mouse
ALYREF 5008 5231
AQR 3952 3898
BCAS2 4926 -2783
BUD31 4578 4660
CASC3 9 1880
CCAR1 3856 -1363
CD2BP2 2749 -1010
CDC40 4670 4455
CDC5L 2693 2309
CHERP 4498 4178
CLP1 4787 5127
CPSF1 -3670 1693
CPSF2 -922 1961
CPSF3 1953 -1
CPSF4 862 4036
CPSF7 407 2081
CRNKL1 4682 2187
CSTF1 2216 2463
CSTF2 1437 -2189
CSTF2T 2703 4265
CSTF3 -2793 4044
CTNNBL1 -145 2378
CWC15 4989 -2691
CWC22 4974 3311
CWC27 1809 -3152
DDX23 -645 -3513
DDX42 2929 4157
DDX46 2094 -1739
DDX5 4191 -2760
DHX15 2483 4240
DHX16 3981 306
DHX38 2857 -865
DHX9 4151 322
DNAJC8 4247 1747
EFTUD2 1157 3818
EIF4A3 4491 3824
ELAVL1 2256 2925
FIP1L1 3587 1848
FUS 867 4337
GCFC2 4300 143
GPKOW 590 2936
GTF2F1 4999 4919
GTF2F2 4067 5069
HNRNPA0 2412 4465
HNRNPA1 3878 3701
HNRNPA2B1 3693 -2053
HNRNPA3 2505 2697
HNRNPC 3406 2818
HNRNPD 4343 2983
HNRNPF 4978 4644
HNRNPH1 3339 4865
HNRNPH2 2261 730
HNRNPK 3054 2784
HNRNPL 1064 224
HNRNPM 4022 -3455
HNRNPR 4406 2984
HNRNPU 4229 4421
HNRNPUL1 2433 2224
HSPA8 3674 5088
ISY1 2662 -1226
LSM2 -1347 3340
LSM3 2210 355
LSM4 -2884 -589
LSM5 2324 358
LSM6 -1177 -1931
LSM7 -3487 916
MAGOH 4561 4010
MAGOHB 2239 2185
NCBP1 -1736 4182
NCBP2 4188 264
NUDT21 3626 3457
PCBP1 -3158 3122
PCF11 -1597 -2897
PDCD7 4447 5165
PHF5A 3478 1234
PLRG1 4237 138
POLR2A 3861 5046
POLR2B 4509 -4119
POLR2C 4529 -904
POLR2D 1669 2692
POLR2E -667 1599
POLR2G 89 5112
POLR2H -3927 3497
POLR2I -154 81
POLR2K 2480 -1584
POLR2L -4314 4110
PPIE 2144 896
PPIH 594 369
PPIL1 863 1860
PPIL3 4044 -1466
PPIL4 3657 -214
PPWD1 2992 -1498
PQBP1 -379 -1361
PRCC 2656 2793
PRPF19 2441 -4538
PRPF3 4719 4411
PRPF31 1339 4183
PRPF38A 4433 2282
PRPF4 3652 -2192
PRPF40A 4797 2652
PRPF6 684 2501
PRPF8 2926 -4269
PTBP1 3063 4257
PUF60 -2093 2016
RBM17 2520 2504
RBM22 709 2550
RBM5 3930 1290
RNPC3 -3052 951
RNPS1 681 -379
SART1 759 2635
SF1 4412 3687
SF3A1 3470 1896
SF3A2 2302 3304
SF3A3 2871 2756
SF3B1 1067 3140
SF3B2 2676 -1599
SF3B3 3615 4529
SF3B4 4792 4649
SF3B5 1969 3781
SLU7 4893 3614
SMNDC1 4537 3789
SNRNP200 2626 -3909
SNRNP25 2402 -2712
SNRNP27 2641 -1995
SNRNP35 -2744 -3140
SNRNP40 2967 3494
SNRNP48 4305 -939
SNRNP70 -267 -706
SNRPA1 4117 4600
SNRPB 3761 35
SNRPB2 4617 2625
SNRPC 3677 169
SNRPD1 3996 4006
SNRPD2 2043 -304
SNRPD3 2384 -1603
SNRPE 3421 760
SNRPF 3777 2400
SNRPG 3179 3615
SNRPN -2163 -2931
SNW1 3618 4819
SRRM1 2285 -746
SRRM2 -1731 -3957
SRRT 4962 3050
SRSF1 1871 -429
SRSF11 3911 -4703
SRSF3 2586 3185
SRSF4 1929 4093
SRSF5 1997 -2886
SRSF6 1798 3296
SRSF7 3545 4305
SRSF9 3543 3246
SUGP1 -1552 1721
SYF2 4472 2749
SYMPK -3207 -2811
TFIP11 5002 3365
TRA2B 4288 4466
TXNL4A -698 1687
U2AF2 4337 3060
U2SURP 4199 -2963
UPF3B 1586 -4316
USP39 1526 2994
WBP11 4711 4773
WBP4 3659 -1633
WDR33 3143 1005
XAB2 2348 1369
YBX1 -681 1282
ZCRB1 833 -1382
ZMAT5 1059 360
ZRSR2 4437 -1079



rRNA processing in the nucleus and cytosol

rRNA processing in the nucleus and cytosol
metric value
setSize 143
pMANOVA 2.44e-22
p.adjustMANOVA 6.01e-20
s.dist 0.523
s.human 0.367
s.mouse 0.372
p.human 4.03e-14
p.mouse 1.75e-14




Top 20 genes
Gene human mouse
UTP14A 4777 5037.5
DDX21 4868 4778.0
NOP58 4891 4343.0
DCAF13 4800 4163.0
GAR1 4132 4763.0
LTV1 4806 3985.0
HEATR1 4911 3855.0
FTSJ3 4444 3950.0
WDR3 4838 3546.0
WDR43 4883 3479.0
GNL3 4434 3817.0
NOP2 3472 4824.0
WDR36 4542 3505.0
PES1 4214 3692.0
TSR1 3117 4777.0
ISG20L2 3385 4293.0
UTP3 4917 2928.0
UTP18 3851 3736.0
RPL22L1 3380 4103.0
NCL 3573 3720.0

Click HERE to show all gene set members

All member genes
human mouse
BMS1 3511 -4218.0
BYSL 2701 1951.0
C1D 3347 -3256.0
CSNK1D -3539 3832.0
CSNK1E -5045 816.0
DCAF13 4800 4163.0
DDX21 4868 4778.0
DDX47 3735 1436.0
DDX49 2178 4026.0
DHX37 2105 2976.0
DIEXF 4877 1147.0
DIMT1 2537 1451.0
DIS3 4973 1390.0
DKC1 3629 -171.0
EBNA1BP2 4030 -1311.0
ERI1 2910 3935.0
EXOSC1 1073 2615.0
EXOSC10 4991 893.0
EXOSC2 3309 3785.0
EXOSC3 3331 2172.0
EXOSC4 2447 -1601.0
EXOSC5 20 -1868.0
EXOSC7 -4980 510.0
EXOSC8 3102 2426.0
EXOSC9 4106 1068.0
FAU 2272 4115.0
FBL 4233 2213.0
FCF1 3303 2053.0
FTSJ3 4444 3950.0
GAR1 4132 4763.0
GNL3 4434 3817.0
HEATR1 4911 3855.0
IMP3 4536 -961.0
IMP4 2805 4315.0
ISG20L2 3385 4293.0
KRR1 3921 1112.0
LAS1L 3707 -281.0
LTV1 4806 3985.0
MPHOSPH10 3928 2826.0
MPHOSPH6 2298 3067.0
NAT10 3642 -1157.0
NCL 3573 3720.0
NHP2 694 2676.0
NIP7 3751 2512.0
NOB1 3229 3188.0
NOC4L 1763 2013.0
NOL11 4916 -392.0
NOL6 3819 2763.0
NOL9 4679 2138.0
NOP10 1336 911.0
NOP14 1590 4393.0
NOP2 3472 4824.0
NOP56 3099 3859.0
NOP58 4891 4343.0
PDCD11 -1465 815.0
PELP1 2605 1120.0
PES1 4214 3692.0
PNO1 4623 332.0
PWP2 2462 745.0
RBM28 4327 107.0
RCL1 3257 -48.0
RIOK1 3760 1972.0
RIOK3 -1480 -2083.0
RPL10 -3902 3841.0
RPL11 -2249 2690.0
RPL14 433 1505.0
RPL18 -1782 3926.0
RPL18A -2969 1546.0
RPL19 -502 2402.0
RPL22 1231 -695.0
RPL22L1 3380 4103.0
RPL23 -115 2472.0
RPL26 1047 3247.0
RPL28 -391 2871.0
RPL3 -786 4892.0
RPL30 286 2070.0
RPL31 -595 4273.0
RPL32 -367 2766.0
RPL34 1447 1856.0
RPL35A 812 1955.0
RPL36A 1261 2266.0
RPL37 -715 2388.0
RPL37A -1043 2280.0
RPL38 231 3306.0
RPL3L -5212 -3395.0
RPL4 -522 1026.0
RPL5 1206 4486.0
RPL7 1440 1916.0
RPL8 -2775 2474.0
RPLP2 -2469 2383.0
RPP14 2370 -3591.0
RPP30 2968 1226.0
RPP38 3980 247.0
RPP40 3369 -268.0
RPS11 -1582 3395.0
RPS12 -318 3958.0
RPS13 1131 3118.0
RPS14 -1412 1322.0
RPS15 -1799 1989.0
RPS15A -704 2410.0
RPS16 -1828 3864.0
RPS18 -974 2916.0
RPS19 -2045 2954.0
RPS20 -1844 4785.0
RPS21 -1536 707.0
RPS23 -68 1922.0
RPS24 256 1742.0
RPS26 -282 2982.0
RPS27A 783 1840.0
RPS27L -616 298.0
RPS29 -1140 2499.0
RPS3 -544 3102.0
RPS4X 83 1892.0
RPS5 -1577 2419.0
RPS6 -245 3549.0
RPS8 -1593 2271.0
RPS9 -1107 1580.0
RRP1 1063 -1990.0
RRP36 1532 1854.0
RRP7A 2138 3626.0
RRP9 771 2325.0
SENP3 2112 2465.0
TBL3 -1551 1063.0
TEX10 2840 -338.0
THUMPD1 4666 -2564.0
TSR1 3117 4777.0
TSR3 -3611 -3279.0
UTP14A 4777 5037.5
UTP14C 1565 5037.5
UTP15 4137 2775.0
UTP18 3851 3736.0
UTP20 4174 240.0
UTP3 4917 2928.0
UTP6 4779 -4513.0
WBSCR22 1741 -1538.0
WDR12 1739 -3276.0
WDR18 -812 -1113.0
WDR3 4838 3546.0
WDR36 4542 3505.0
WDR43 4883 3479.0
WDR46 3335 2646.0
WDR75 3743 2374.0
XRN2 4296 1666.0



Major pathway of rRNA processing in the nucleolus and cytosol

Major pathway of rRNA processing in the nucleolus and cytosol
metric value
setSize 134
pMANOVA 2.69e-21
p.adjustMANOVA 5.53e-19
s.dist 0.527
s.human 0.358
s.mouse 0.386
p.human 8.79e-13
p.mouse 1.42e-14




Top 20 genes
Gene human mouse
UTP14A 4777 5037.5
DDX21 4868 4778.0
NOP58 4891 4343.0
DCAF13 4800 4163.0
LTV1 4806 3985.0
HEATR1 4911 3855.0
FTSJ3 4444 3950.0
WDR3 4838 3546.0
WDR43 4883 3479.0
GNL3 4434 3817.0
WDR36 4542 3505.0
PES1 4214 3692.0
TSR1 3117 4777.0
ISG20L2 3385 4293.0
UTP3 4917 2928.0
UTP18 3851 3736.0
RPL22L1 3380 4103.0
NCL 3573 3720.0
EXOSC2 3309 3785.0
IMP4 2805 4315.0

Click HERE to show all gene set members

All member genes
human mouse
BMS1 3511 -4218.0
BYSL 2701 1951.0
C1D 3347 -3256.0
CSNK1D -3539 3832.0
CSNK1E -5045 816.0
DCAF13 4800 4163.0
DDX21 4868 4778.0
DDX47 3735 1436.0
DDX49 2178 4026.0
DHX37 2105 2976.0
DIEXF 4877 1147.0
DIS3 4973 1390.0
EBNA1BP2 4030 -1311.0
ERI1 2910 3935.0
EXOSC1 1073 2615.0
EXOSC10 4991 893.0
EXOSC2 3309 3785.0
EXOSC3 3331 2172.0
EXOSC4 2447 -1601.0
EXOSC5 20 -1868.0
EXOSC7 -4980 510.0
EXOSC8 3102 2426.0
EXOSC9 4106 1068.0
FAU 2272 4115.0
FBL 4233 2213.0
FCF1 3303 2053.0
FTSJ3 4444 3950.0
GNL3 4434 3817.0
HEATR1 4911 3855.0
IMP3 4536 -961.0
IMP4 2805 4315.0
ISG20L2 3385 4293.0
KRR1 3921 1112.0
LAS1L 3707 -281.0
LTV1 4806 3985.0
MPHOSPH10 3928 2826.0
MPHOSPH6 2298 3067.0
NCL 3573 3720.0
NIP7 3751 2512.0
NOB1 3229 3188.0
NOC4L 1763 2013.0
NOL11 4916 -392.0
NOL6 3819 2763.0
NOL9 4679 2138.0
NOP14 1590 4393.0
NOP56 3099 3859.0
NOP58 4891 4343.0
PDCD11 -1465 815.0
PELP1 2605 1120.0
PES1 4214 3692.0
PNO1 4623 332.0
PWP2 2462 745.0
RBM28 4327 107.0
RCL1 3257 -48.0
RIOK1 3760 1972.0
RIOK3 -1480 -2083.0
RPL10 -3902 3841.0
RPL11 -2249 2690.0
RPL14 433 1505.0
RPL18 -1782 3926.0
RPL18A -2969 1546.0
RPL19 -502 2402.0
RPL22 1231 -695.0
RPL22L1 3380 4103.0
RPL23 -115 2472.0
RPL26 1047 3247.0
RPL28 -391 2871.0
RPL3 -786 4892.0
RPL30 286 2070.0
RPL31 -595 4273.0
RPL32 -367 2766.0
RPL34 1447 1856.0
RPL35A 812 1955.0
RPL36A 1261 2266.0
RPL37 -715 2388.0
RPL37A -1043 2280.0
RPL38 231 3306.0
RPL3L -5212 -3395.0
RPL4 -522 1026.0
RPL5 1206 4486.0
RPL7 1440 1916.0
RPL8 -2775 2474.0
RPLP2 -2469 2383.0
RPP14 2370 -3591.0
RPP30 2968 1226.0
RPP38 3980 247.0
RPP40 3369 -268.0
RPS11 -1582 3395.0
RPS12 -318 3958.0
RPS13 1131 3118.0
RPS14 -1412 1322.0
RPS15 -1799 1989.0
RPS15A -704 2410.0
RPS16 -1828 3864.0
RPS18 -974 2916.0
RPS19 -2045 2954.0
RPS20 -1844 4785.0
RPS21 -1536 707.0
RPS23 -68 1922.0
RPS24 256 1742.0
RPS26 -282 2982.0
RPS27A 783 1840.0
RPS27L -616 298.0
RPS29 -1140 2499.0
RPS3 -544 3102.0
RPS4X 83 1892.0
RPS5 -1577 2419.0
RPS6 -245 3549.0
RPS8 -1593 2271.0
RPS9 -1107 1580.0
RRP1 1063 -1990.0
RRP36 1532 1854.0
RRP7A 2138 3626.0
RRP9 771 2325.0
SENP3 2112 2465.0
TBL3 -1551 1063.0
TEX10 2840 -338.0
TSR1 3117 4777.0
UTP14A 4777 5037.5
UTP14C 1565 5037.5
UTP15 4137 2775.0
UTP18 3851 3736.0
UTP20 4174 240.0
UTP3 4917 2928.0
UTP6 4779 -4513.0
WBSCR22 1741 -1538.0
WDR12 1739 -3276.0
WDR18 -812 -1113.0
WDR3 4838 3546.0
WDR36 4542 3505.0
WDR43 4883 3479.0
WDR46 3335 2646.0
WDR75 3743 2374.0
XRN2 4296 1666.0



Muscle contraction

Muscle contraction
metric value
setSize 120
pMANOVA 4.8e-20
p.adjustMANOVA 8.45e-18
s.dist 0.518
s.human -0.493
s.mouse -0.157
p.human 1.12e-20
p.mouse 0.00311




Top 20 genes
Gene human mouse
ATP1A2 -5569 -5156
DMPK -5518 -5197
SCN4A -5601 -5087
CACNB1 -5285 -5348
PAK1 -5419 -4885
SCN1B -4899 -5314
MYBPC2 -5048 -5125
ATP2A1 -5479 -4584
CAMK2A -5527 -4430
CACNG6 -5276 -4552
RYR1 -5289 -4536
TMOD1 -5339 -4444
CAMK2B -5497 -4230
ATP2B3 -4422 -5220
SORBS3 -5064 -4309
MYL3 -3976 -5357
SLC8A3 -5477 -3886
NOS1 -4260 -4935
KCNJ12 -5368 -3855
KCNJ2 -4246 -4660

Click HERE to show all gene set members

All member genes
human mouse
ABCC9 -3151 -5198
ACTA2 -3819 3676
ACTN2 -3104 3454
AHCYL1 -3386 988
AKAP9 -573 -5181
ANXA1 537 4544
ANXA2 -4123 5025
ANXA6 -5097 4029
ASPH -3277 -2678
ATP1A1 -4096 4907
ATP1A2 -5569 -5156
ATP1A3 206 3822
ATP1B1 2576 -3091
ATP1B3 -598 3075
ATP2A1 -5479 -4584
ATP2A2 -2976 515
ATP2A3 -4467 1862
ATP2B1 2034 159
ATP2B3 -4422 -5220
ATP2B4 -2762 -68
CACNA1C -762 -668
CACNB1 -5285 -5348
CACNG6 -5276 -4552
CALD1 3357 3283
CALM1 -4464 96
CAMK2A -5527 -4430
CAMK2B -5497 -4230
CAMK2D -2223 4137
CAMK2G -2097 -4962
CAV3 -5286 1920
DES -4740 4798
DMD -2970 -4510
DMPK -5518 -5197
DYSF -4799 4349
FGF11 -3896 -3735
FGF13 -844 616
FXYD1 -2722 -3530
GUCY1B3 4506 -4233
HIPK1 4147 3646
HIPK2 -4312 -2060
ITGA1 1757 -4136
ITGB5 -2578 -4797
ITPR1 4903 -2230
ITPR2 1242 -3115
ITPR3 -3631 -3441
KAT2B -3340 -5260
KCNE4 -764 2481
KCNH2 -3531 -1483
KCNJ11 -5488 -2118
KCNJ12 -5368 -3855
KCNJ2 -4246 -4660
KCNK2 -480 -2148
KCNK6 -1417 2020
KCNQ1 -3887 564
LMOD1 -4937 443
MYBPC1 -4465 -758
MYBPC2 -5048 -5125
MYH3 -4216 -2162
MYH6 -4746 1905
MYH8 -4002 4013
MYL1 -1989 -3616
MYL10 -3328 571
MYL12A 84 5226
MYL12B 1563 1984
MYL2 -4849 566
MYL3 -3976 -5357
MYL4 -4626 -2026
MYL6 -3628 4190
MYL6B -4219 657
MYL9 -4777 11
MYLK -3879 -1681
MYLPF -4355 -4146
NEB -2805 -4575
NOS1 -4260 -4935
NPR2 -3578 -5044
ORAI2 936 811
PAK1 -5419 -4885
PAK2 1525 4805
PLN -2060 814
PRKACA -4691 -1606
PXN -4750 204
RANGRF -4019 157
RYR1 -5289 -4536
RYR3 -2435 351
SCN1B -4899 -5314
SCN2A 544 316
SCN2B -4268 -1921
SCN3A 2439 4422
SCN3B -3892 2980
SCN4A -5601 -5087
SCN5A -5309 3520
SLC8A1 754 -3579
SLC8A3 -5477 -3886
SORBS1 -3741 -4308
SORBS3 -5064 -4309
SRI -4069 3480
STIM1 -3417 -2324
TCAP -5032 -2912
TLN1 -3918 2975
TMOD1 -5339 -4444
TMOD2 -2848 -138
TMOD3 376 1007
TNNC1 -4638 612
TNNC2 -4220 -1789
TNNI1 -3744 -976
TNNI2 -4910 -3398
TNNT1 -4248 -1116
TNNT2 -3984 -390
TNNT3 -4247 -3376
TPM1 -4592 -4022
TPM2 -3443 -4506
TPM3 -3868 2581
TPM4 191 4657
TRDN -3364 -5213
TRIM72 -5057 1788
TRPC1 1744 -577
TTN 3968 -4448
VCL -4538 5034
VIM -3027 4772
WWTR1 -2503 809



Infectious disease

Infectious disease
metric value
setSize 533
pMANOVA 2.75e-19
p.adjustMANOVA 4.24e-17
s.dist 0.248
s.human 0.0913
s.mouse 0.231
p.human 0.000374
p.mouse 2.14e-19




Top 20 genes
Gene human mouse
TAF4B 4967 5209.0
HSPA1A 4887 5277.5
GTF2F1 4999 4919.0
TAF7 4717 4909.0
EZH2 4698 4740.0
GTF2B 4276 5124.0
GTF2A1 4730 4588.0
NUP98 4235 5066.0
PLK2 4764 4365.0
GTF2F2 4067 5069.0
BRD4 4547 4468.0
PTGER4 4219 4674.0
POLR2A 3861 5046.0
HSP90AA1 3656 5261.0
TAF3 4294 4474.0
TRIM28 4209 4460.0
DAXX 4449 4197.0
TRIM27 4120 4461.0
HBEGF 3484 5272.0
SFPQ 4544 3976.0

Click HERE to show all gene set members

All member genes
human mouse
AAAS -3476 1550.0
ABI1 3792 2553.0
ABI2 -308 5048.0
ABL1 -4533 -3545.0
ACTB 940 4977.0
ACTG1 -3075 4986.0
ACTR2 3547 3933.0
ACTR3 1376 5136.0
ADAM17 2407 2079.0
ADCY1 -3780 -1927.0
ADCY2 -4820 -3731.0
ADCY3 338 187.0
ADCY5 1967 1780.0
ADCY6 -4515 -4206.0
ADCY7 -2820 2292.0
ADCY9 -4889 -4292.0
ADM -1822 -3261.0
ADRB2 -1092 -2389.0
AHCYL1 -3386 988.0
ANTXR1 -1237 -965.0
ANTXR2 -1075 1180.0
AP1B1 -4552 -34.0
AP1G1 4140 2569.0
AP1M1 3732 1437.0
AP1S1 -1410 812.0
AP1S2 -1634 1536.0
AP2A1 -3632 -420.0
AP2A2 -1058 5063.0
AP2B1 -1157 2251.0
AP2M1 -2746 3372.0
AP2S1 1777 1981.0
ARF1 566 4500.0
ARID4A 4673 -1405.0
ARID4B 4763 -2509.0
ARPC1A -120 2648.0
ARPC1B 669 4856.0
ARPC2 1357 4617.0
ARPC3 2873 3762.0
ARPC4 1698 2568.0
ARPC5 2295 4844.0
ATP1A1 -4096 4907.0
ATP1A2 -5569 -5156.0
ATP1A3 206 3822.0
ATP1B1 2576 -3091.0
ATP1B3 -598 3075.0
ATP6V1H -57 4488.0
B2M -731 1593.0
BAIAP2 -641 5041.0
BANF1 -2281 674.0
BECN1 3274 -3060.0
BRD4 4547 4468.0
BRK1 2026 3096.0
BRMS1 -28 2515.0
BTRC -1187 -2758.0
C3 4311 1838.0
CALCRL 2945 -4855.0
CALM1 -4464 96.0
CALR 1534 4995.0
CANX -836 4736.0
CASP1 -1298 3173.0
CBL 1736 183.0
CBLL1 4088 2387.0
CBX1 3736 453.0
CCNH 3825 -1657.0
CCNK 3139 154.0
CCNT1 4896 -1160.0
CCNT2 4381 -5015.0
CD28 -2910 -5023.0
CD9 2203 2358.0
CDC42 3308 754.0
CDK7 1571 -2032.0
CDK9 -1348 4462.0
CHD3 -3721 -4142.0
CHD4 -4283 464.0
CHMP1A 2879 123.0
CHMP2A 1155 2310.0
CHMP2B 967 -4167.0
CHMP3 -3919 1578.0
CHMP4B -1125 329.0
CHMP5 3372 -357.0
CHMP6 -4368 279.0
CHMP7 1743 -3701.0
CLTA 1218 1668.0
CLTC 2268 -2802.0
COMT -5098 -1696.0
CPSF4 862 4036.0
CRBN -992 -4556.0
CREB1 2179 -4329.0
CRK 2145 2262.0
CTDP1 2071 4335.0
CTNNB1 1714 -780.0
CTNND1 949 4751.0
CUL5 2599 -3195.0
CYBA -633 3083.0
CYFIP2 -3775 -1129.0
CYSLTR1 -4110 4015.0
DAD1 498 2970.0
DAXX 4449 4197.0
DBP -538 -5331.0
DDOST 320 4699.0
DDX5 4191 -2760.0
DNAJC3 1950 1334.0
DOCK1 -226 -41.0
DUSP16 3082 2356.0
DUT -592 540.0
DVL1 -5428 -3357.0
DVL2 -2215 -2076.0
DVL3 -4897 87.0
DYNC1H1 -1442 -2348.0
DYNC1I2 2591 -2971.0
DYNC1LI1 2883 1316.0
DYNC1LI2 1750 -1620.0
DYNLL1 -1331 4245.0
EDEM2 1319 3509.0
EED 3304 3671.0
EEF2 -2853 -853.0
EGFR 424 1475.0
EIF2AK2 -486 -749.0
ELK1 -3862 -42.0
ELL -3990 3019.0
ELMO1 -2166 1449.0
ELMO2 -354 416.0
ENO1 -4083 2473.0
ENTPD5 -4035 -3417.0
EPS15 5 -4281.0
ERCC2 824 2393.0
ERCC3 473 1570.0
EZH2 4698 4740.0
FAU 2272 4115.0
FEN1 4094 3551.0
FKBP4 1305 500.0
FURIN -4221 4117.0
FUT8 3313 438.0
FXYD1 -2722 -3530.0
FYN -2850 3685.0
FZD7 1006 -4275.0
GALNT1 1478 1252.0
GANAB 489 2629.0
GATAD2A -975 4779.0
GATAD2B 304 3259.0
GGT5 -954 -1159.0
GNAI1 183 -419.0
GNAI2 800 3632.0
GNAI3 4221 3815.0
GNAS -3163 -641.0
GNB1 177 4937.0
GNB2 -3870 3905.0
GNB3 -3272 -1723.0
GNB4 -3491 -3375.0
GNB5 879 160.0
GNG11 4695 -2336.0
GNG12 612 -821.0
GNG2 802 -279.0
GNG5 415 -1583.0
GNG7 -2742 -5085.0
GPS2 2002 3298.0
GRB2 -4050 4496.0
GRSF1 -3131 -4623.0
GSK3A 3319 -75.0
GSK3B 897 3200.0
GTF2A1 4730 4588.0
GTF2A2 4648 -1742.0
GTF2B 4276 5124.0
GTF2E1 2188 1803.0
GTF2E2 2041 120.0
GTF2F1 4999 4919.0
GTF2F2 4067 5069.0
GTF2H1 3886 1058.0
GTF2H2 4419 -2446.5
GTF2H3 -1925 467.0
GTF2H5 -878 -1711.0
HBEGF 3484 5272.0
HDAC2 4386 -1101.0
HDAC3 -178 -4320.0
HGS 2410 4643.0
HMG20B 704 291.0
HMGA1 598 5099.0
HNRNPK 3054 2784.0
HSP90AA1 3656 5261.0
HSP90AB1 -639 4629.0
HSPA1A 4887 5277.5
HTR7 2315 -1558.0
IFNAR1 3645 1085.0
IFNAR2 -1316 2360.0
IFNGR1 2506 2475.0
IFNGR2 -386 -4286.0
IL1R1 -3018 3910.0
IL6R -5515 3267.0
IMPDH1 -827 2546.0
IMPDH2 822 1907.0
IPO5 1982 3806.0
IRS1 -5550 -5121.0
ISG15 -3928 1737.0
ITGA4 -2878 -5141.0
ITGB1 956 4614.0
ITPR1 4903 -2230.0
ITPR2 1242 -3115.0
ITPR3 -3631 -3441.0
JAK1 -1869 4228.0
JAK2 -2569 -5057.0
JUN 2469 5225.0
KDM1A 249 4852.0
KPNA1 1833 3439.0
KPNA2 5007 3593.0
KPNA3 -2337 -1621.0
KPNA4 1501 4518.0
KPNB1 3619 3517.0
LIG1 -3127 3257.0
LIG4 2394 -3296.0
LYN 785 3984.0
MAGT1 1192 -1341.0
MAN1B1 -2087 -721.0
MAN2A1 4002 1427.0
MAP1LC3B 2569 -3268.0
MAP2K1 -506 -2643.0
MAP2K2 -3813 -1797.0
MAP2K3 -4716 3039.0
MAP2K4 8 -3251.0
MAP2K6 1456 -4876.0
MAP2K7 794 -3887.0
MAPK1 1988 -648.0
MAPK14 -1562 -1635.0
MAPK3 -1024 3725.0
MAPK8 457 1106.0
MBD3 -3419 1364.0
MET -3529 2929.0
MGAT1 -1603 -2422.0
MGAT2 1418 4950.0
MGAT4A 268 3317.0
MGAT4B -4707 -1206.0
MGAT5 3014 2727.0
MNAT1 830 -2433.0
MOGS -3129 4652.0
MTA1 -4102 4542.0
MTA2 3682 946.0
MTA3 -2123 -1614.0
MVB12A -2807 711.0
MVB12B -5576 -5074.0
MYH2 -3080 -857.0
MYH9 -1879 4194.0
MYO10 1381 294.0
MYO1C -4842 3521.0
MYO5A -885 3279.0
MYO9B -1901 4055.0
NCBP1 -1736 4182.0
NCBP2 4188 264.0
NCK1 3718 1288.0
NCKAP1 3563 3585.0
NCKIPSD -2821 704.0
NCOR1 2625 -3925.0
NCOR2 -5167 -1521.0
NDC1 1273 -2350.0
NEDD4L 4279 -2158.0
NELFA 356 3929.0
NELFB -1196 2773.0
NELFCD 1896 -2294.0
NELFE -2178 3334.0
NFKB1 -4233 3315.0
NFKB2 -3926 3336.0
NMT1 -1463 3596.0
NMT2 2059 2124.0
NR3C1 985 -4192.0
NT5E 1998 -3634.0
NUP107 3232 2949.0
NUP133 889 -4048.0
NUP153 4762 1533.0
NUP155 4306 -2233.0
NUP160 3998 1035.0
NUP188 2117 3830.0
NUP205 4438 3588.0
NUP214 3124 665.0
NUP35 4571 649.0
NUP37 -327 192.0
NUP43 4562 2216.0
NUP54 4508 3831.0
NUP85 3181 -393.0
NUP88 1244 2212.0
NUP93 -1503 3903.0
NUP98 4235 5066.0
P2RX4 -1108 2865.0
PACS1 -4826 1664.0
PAK2 1525 4805.0
PARP1 -2423 -2631.0
PARP10 -4978 -2806.0
PARP14 -1721 -1087.0
PARP16 -79 -2268.0
PARP4 -4440 2701.0
PARP6 448 419.0
PARP8 4194 1232.0
PARP9 -3114 22.0
PDCD6IP 1350 4607.0
PGK1 -1414 -3515.0
PHF21A -4739 -629.0
PIK3C3 3439 -1648.0
PIK3R4 3839 -3531.0
PLCG1 -3955 -4939.0
PLK2 4764 4365.0
PML 3338 3449.0
POLR2A 3861 5046.0
POLR2B 4509 -4119.0
POLR2C 4529 -904.0
POLR2D 1669 2692.0
POLR2E -667 1599.0
POLR2G 89 5112.0
POLR2H -3927 3497.0
POLR2I -154 81.0
POLR2K 2480 -1584.0
POLR2L -4314 4110.0
PPIA -4031 4697.0
PRKACA -4691 -1606.0
PRKACB -2659 -1546.0
PRKAR1A -3106 3030.0
PRKAR1B -2442 2761.0
PRKAR2A -2664 -655.0
PRKAR2B 3460 2616.0
PRKCSH -268 539.0
PRKX -1471 4883.0
PSIP1 3390 2882.0
PSMA1 2820 3328.0
PSMA3 3434 -4.0
PSMA4 769 958.0
PSMA6 2199 -1044.0
PSMA7 -2980 976.0
PSMB1 954 2628.0
PSMB10 -1800 2907.0
PSMB2 618 2471.0
PSMB4 -235 2096.0
PSMB5 -4113 -606.0
PSMB6 -793 914.0
PSMB7 -831 -1453.0
PSMB8 -675 2066.0
PSMB9 -1611 -2973.0
PSMC1 449 -336.0
PSMC2 -1311 3241.0
PSMC3 -2439 -369.0
PSMC4 2724 1416.0
PSMC5 1212 -1123.0
PSMC6 -2520 3423.0
PSMD1 2619 -1191.0
PSMD10 -1227 525.0
PSMD11 995 5183.0
PSMD12 3831 536.0
PSMD13 821 1665.0
PSMD14 -635 3816.0
PSMD2 -713 -555.0
PSMD3 -3343 2226.0
PSMD4 -214 2558.0
PSMD5 1807 3558.0
PSMD6 3537 -2207.0
PSMD7 -2329 1233.0
PSMD8 -3171 4626.0
PSMD9 4204 -970.0
PSME1 -2771 3350.0
PSME2 -4085 3584.0
PSME3 3333 3379.0
PSME4 1960 -4574.0
PSMF1 683 -1480.0
PTGER4 4219 4674.0
PTGES3 1328 3635.0
PTGIR -370 3143.0
PTH1R -2770 -1748.0
PTHLH -3836 1237.0
PTK2 -2497 -1508.0
PYCARD -2810 4703.0
RAB5A 2109 4941.0
RAB7A -383 1499.0
RAC1 2525 1457.0
RAE1 4471 2389.0
RAMP1 -5448 209.0
RAN 2329 1938.0
RANBP1 745 4765.0
RANBP2 4470 -3848.0
RANGAP1 483 4340.0
RB1 -2449 1464.0
RBBP4 1072 2469.0
RBBP7 -924 -2291.0
RBX1 -733 -968.0
RCC1 997 3619.0
RCOR1 4776 -5.0
RELA 1783 4531.0
REST 1113 2305.0
RHBDF2 -2750 -644.0
RIPK1 325 719.0
RNF213 -4087 -1339.0
RNGTT 4414 1057.0
RNMT 4864 -807.0
ROCK1 4876 -54.0
ROCK2 2205 314.0
RPL10 -3902 3841.0
RPL11 -2249 2690.0
RPL14 433 1505.0
RPL18 -1782 3926.0
RPL18A -2969 1546.0
RPL19 -502 2402.0
RPL22 1231 -695.0
RPL22L1 3380 4103.0
RPL23 -115 2472.0
RPL26 1047 3247.0
RPL28 -391 2871.0
RPL3 -786 4892.0
RPL30 286 2070.0
RPL31 -595 4273.0
RPL32 -367 2766.0
RPL34 1447 1856.0
RPL35A 812 1955.0
RPL36A 1261 2266.0
RPL37 -715 2388.0
RPL37A -1043 2280.0
RPL38 231 3306.0
RPL3L -5212 -3395.0
RPL4 -522 1026.0
RPL5 1206 4486.0
RPL7 1440 1916.0
RPL8 -2775 2474.0
RPLP2 -2469 2383.0
RPN1 768 1558.0
RPN2 497 3166.0
RPS11 -1582 3395.0
RPS12 -318 3958.0
RPS13 1131 3118.0
RPS14 -1412 1322.0
RPS15 -1799 1989.0
RPS15A -704 2410.0
RPS16 -1828 3864.0
RPS18 -974 2916.0
RPS19 -2045 2954.0
RPS20 -1844 4785.0
RPS21 -1536 707.0
RPS23 -68 1922.0
RPS24 256 1742.0
RPS26 -282 2982.0
RPS27A 783 1840.0
RPS27L -616 298.0
RPS29 -1140 2499.0
RPS3 -544 3102.0
RPS4X 83 1892.0
RPS5 -1577 2419.0
RPS6 -245 3549.0
RPS8 -1593 2271.0
RPS9 -1107 1580.0
S1PR1 2689 1552.0
SAP18 4832 915.0
SAP30 138 3376.0
SAP30L -2519 -2355.0
SEC13 730 1702.0
SEH1L 1085 4263.0
SFPQ 4544 3976.0
SH3GL1 -2937 2592.0
SH3KBP1 1014 -3709.0
SIGMAR1 -3608 2508.0
SKP1 2028 -2504.0
SLC25A4 -1327 -2889.0
SLC25A5 3467 4820.0
SNF8 -1018 -1422.0
SRC -3910 1378.0
SSRP1 1755 3948.0
ST3GAL1 -4505 4024.0
ST3GAL2 -2316 -4984.0
ST3GAL3 -4844 -2274.0
ST3GAL4 -2946 3771.0
ST6GAL1 -5388 1754.0
ST6GALNAC2 -4576 1758.0
ST6GALNAC4 -4958 4122.0
STAM 3932 2747.0
STAM2 3489 2601.0
STAT2 -2601 280.0
STT3A -1709 4540.0
STX1A -411 1613.0
STX1B -468 -1328.0
SUDS3 3840 -2057.0
SUGT1 3140 -4533.0
SUMO1 4213 1399.0
SUPT16H 3885 4363.0
SUPT4H1 3648 -1203.0
SUPT5H 1321 3508.0
SUZ12 3871 1927.0
TAF1 1708 -350.0
TAF10 -273 2957.0
TAF11 2962 -484.0
TAF12 3100 3164.0
TAF13 4749 1567.0
TAF2 4591 3381.0
TAF3 4294 4474.0
TAF4 -1340 3063.0
TAF4B 4967 5209.0
TAF5 4309 2830.0
TAF6 -912 55.0
TAF7 4717 4909.0
TAF9B 1874 519.0
TBK1 673 3485.0
TBL1XR1 1876 -2165.0
TBP 1137 2611.0
TCEA1 4037 647.0
TGFB1 -3111 4943.0
TPR 2984 -1026.0
TRIM27 4120 4461.0
TRIM28 4209 4460.0
TSG101 260 2655.0
TUBB -3118 5070.0
TUSC3 70 2722.0
TXN 1855 4791.0
TXNRD1 -2444 2445.0
TYK2 -3123 -50.0
UBAP1 -1913 4784.0
UBC 2672 4480.0
UBE2I 1246 1214.0
UVRAG 3046 3931.0
VAMP1 -3322 -4688.0
VAMP2 -3293 1812.0
VAV2 -4959 -899.0
VAV3 187 -1063.0
VEGFA -4571 -5196.0
VPS33B 1266 1235.0
VPS36 -3053 -4109.0
VPS37A 1868 -4488.0
VPS37B -3496 2909.0
VPS37C 1403 3419.0
VPS4A -1545 -2086.0
VPS4B 4523 1960.0
VTA1 3283 447.0
WASF2 -4656 1511.0
WASF3 -1015 718.0
WASL 2683 3268.0
WIPF1 -2552 1682.0
WIPF2 3299 -502.0
WIPF3 -5107 -5055.0
WNT5A 1837 -2457.0
XPO1 990 1809.0
XRCC4 -4731 -1301.0
XRCC5 4010 -2853.0
XRCC6 3225 -1241.0
YES1 -176 -2941.0
ZCRB1 833 -1382.0



rRNA processing

rRNA processing
metric value
setSize 154
pMANOVA 3.77e-19
p.adjustMANOVA 5.17e-17
s.dist 0.465
s.human 0.338
s.mouse 0.319
p.human 4.82e-13
p.mouse 8.91e-12




Top 20 genes
Gene human mouse
UTP14A 4777 5037.5
DDX21 4868 4778.0
NOP58 4891 4343.0
DCAF13 4800 4163.0
GAR1 4132 4763.0
LTV1 4806 3985.0
HEATR1 4911 3855.0
FTSJ3 4444 3950.0
WDR3 4838 3546.0
WDR43 4883 3479.0
GNL3 4434 3817.0
NOP2 3472 4824.0
WDR36 4542 3505.0
PES1 4214 3692.0
TSR1 3117 4777.0
ISG20L2 3385 4293.0
UTP3 4917 2928.0
UTP18 3851 3736.0
RPL22L1 3380 4103.0
NCL 3573 3720.0

Click HERE to show all gene set members

All member genes
human mouse
BMS1 3511 -4218.0
BYSL 2701 1951.0
C1D 3347 -3256.0
CSNK1D -3539 3832.0
CSNK1E -5045 816.0
DCAF13 4800 4163.0
DDX21 4868 4778.0
DDX47 3735 1436.0
DDX49 2178 4026.0
DHX37 2105 2976.0
DIEXF 4877 1147.0
DIMT1 2537 1451.0
DIS3 4973 1390.0
DKC1 3629 -171.0
EBNA1BP2 4030 -1311.0
ELAC2 1520 1569.0
ERI1 2910 3935.0
EXOSC1 1073 2615.0
EXOSC10 4991 893.0
EXOSC2 3309 3785.0
EXOSC3 3331 2172.0
EXOSC4 2447 -1601.0
EXOSC5 20 -1868.0
EXOSC7 -4980 510.0
EXOSC8 3102 2426.0
EXOSC9 4106 1068.0
FAU 2272 4115.0
FBL 4233 2213.0
FCF1 3303 2053.0
FTSJ3 4444 3950.0
GAR1 4132 4763.0
GNL3 4434 3817.0
HEATR1 4911 3855.0
HSD17B10 -1193 -485.0
IMP3 4536 -961.0
IMP4 2805 4315.0
ISG20L2 3385 4293.0
KRR1 3921 1112.0
LAS1L 3707 -281.0
LTV1 4806 3985.0
MPHOSPH10 3928 2826.0
MPHOSPH6 2298 3067.0
MT-CO1 -3167 -4114.0
MT-CYB -1355 -2353.0
MT-ND1 -353 -2211.0
MT-ND2 -1120 -2087.0
MT-ND4 -2086 -1594.0
MT-ND5 -3244 -2323.0
NAT10 3642 -1157.0
NCL 3573 3720.0
NHP2 694 2676.0
NIP7 3751 2512.0
NOB1 3229 3188.0
NOC4L 1763 2013.0
NOL11 4916 -392.0
NOL6 3819 2763.0
NOL9 4679 2138.0
NOP10 1336 911.0
NOP14 1590 4393.0
NOP2 3472 4824.0
NOP56 3099 3859.0
NOP58 4891 4343.0
NSUN4 -830 -5028.0
PDCD11 -1465 815.0
PELP1 2605 1120.0
PES1 4214 3692.0
PNO1 4623 332.0
PWP2 2462 745.0
RBM28 4327 107.0
RCL1 3257 -48.0
RIOK1 3760 1972.0
RIOK3 -1480 -2083.0
RPL10 -3902 3841.0
RPL11 -2249 2690.0
RPL14 433 1505.0
RPL18 -1782 3926.0
RPL18A -2969 1546.0
RPL19 -502 2402.0
RPL22 1231 -695.0
RPL22L1 3380 4103.0
RPL23 -115 2472.0
RPL26 1047 3247.0
RPL28 -391 2871.0
RPL3 -786 4892.0
RPL30 286 2070.0
RPL31 -595 4273.0
RPL32 -367 2766.0
RPL34 1447 1856.0
RPL35A 812 1955.0
RPL36A 1261 2266.0
RPL37 -715 2388.0
RPL37A -1043 2280.0
RPL38 231 3306.0
RPL3L -5212 -3395.0
RPL4 -522 1026.0
RPL5 1206 4486.0
RPL7 1440 1916.0
RPL8 -2775 2474.0
RPLP2 -2469 2383.0
RPP14 2370 -3591.0
RPP30 2968 1226.0
RPP38 3980 247.0
RPP40 3369 -268.0
RPS11 -1582 3395.0
RPS12 -318 3958.0
RPS13 1131 3118.0
RPS14 -1412 1322.0
RPS15 -1799 1989.0
RPS15A -704 2410.0
RPS16 -1828 3864.0
RPS18 -974 2916.0
RPS19 -2045 2954.0
RPS20 -1844 4785.0
RPS21 -1536 707.0
RPS23 -68 1922.0
RPS24 256 1742.0
RPS26 -282 2982.0
RPS27A 783 1840.0
RPS27L -616 298.0
RPS29 -1140 2499.0
RPS3 -544 3102.0
RPS4X 83 1892.0
RPS5 -1577 2419.0
RPS6 -245 3549.0
RPS8 -1593 2271.0
RPS9 -1107 1580.0
RRP1 1063 -1990.0
RRP36 1532 1854.0
RRP7A 2138 3626.0
RRP9 771 2325.0
SENP3 2112 2465.0
TBL3 -1551 1063.0
TEX10 2840 -338.0
TFB1M 1537 -3367.0
THUMPD1 4666 -2564.0
TRMT10C 4780 -8.0
TSR1 3117 4777.0
TSR3 -3611 -3279.0
UTP14A 4777 5037.5
UTP14C 1565 5037.5
UTP15 4137 2775.0
UTP18 3851 3736.0
UTP20 4174 240.0
UTP3 4917 2928.0
UTP6 4779 -4513.0
WBSCR22 1741 -1538.0
WDR12 1739 -3276.0
WDR18 -812 -1113.0
WDR3 4838 3546.0
WDR36 4542 3505.0
WDR43 4883 3479.0
WDR46 3335 2646.0
WDR75 3743 2374.0
XRN2 4296 1666.0



The citric acid (TCA) cycle and respiratory electron transport

The citric acid (TCA) cycle and respiratory electron transport
metric value
setSize 142
pMANOVA 1.02e-18
p.adjustMANOVA 1.26e-16
s.dist 0.468
s.human -0.202
s.mouse -0.423
p.human 3.49e-05
p.mouse 3.92e-18




Top 20 genes
Gene human mouse
D2HGDH -4890 -5334
RXRA -5519 -4191
SDHA -4773 -4591
ACAD9 -4578 -4558
IDH2 -5216 -3854
SLC16A3 -4751 -4158
PDK2 -5450 -3535
OGDH -5268 -3650
ACO2 -3822 -4426
CYC1 -4147 -4031
VDAC1 -2909 -4606
IDH3G -4178 -3128
MT-CO1 -3167 -4114
MDH2 -4361 -2855
UQCRC1 -3333 -3667
COX14 -2772 -4368
SLC25A27 -2478 -4864
MPC1 -3681 -3235
NDUFV1 -4226 -2736
SDHC -3712 -3001

Click HERE to show all gene set members

All member genes
human mouse
ACAD9 -4578 -4558
ACO2 -3822 -4426
ADHFE1 -4039 -2474
BSG -2248 -2113
COQ10A -3553 -2653
COQ10B 4344 4255
COX11 -2860 -1166
COX14 -2772 -4368
COX16 -2259 -1943
COX18 -554 635
COX19 3053 3493
COX20 1104 -2275
COX4I1 -2357 -1289
COX5A -2511 -2550
COX5B -2559 458
COX6A1 2259 2241
COX6B1 -2231 -855
COX6C -18 -845
COX7B 144 -729
COX7C -1495 -176
COX8A -4337 2642
CS 3653 -3566
CYC1 -4147 -4031
D2HGDH -4890 -5334
DLAT -1960 -3824
DLD 1187 -4737
DLST -323 -3527
ECSIT -2655 -2846
ETFA 3160 -2761
ETFB -3614 -2740
ETFDH 1884 -4586
FAHD1 -1771 -4302
FH 287 -2895
GLO1 -678 -3885
GSTZ1 -2068 -4631
HAGH -4509 1245
IDH2 -5216 -3854
IDH3A -2155 -3823
IDH3B -2881 -2173
IDH3G -4178 -3128
L2HGDH -262 -3641
LDHA -3251 -2911
LDHB -1491 -1974
LRPPRC 1656 -4390
MDH2 -4361 -2855
ME1 1789 -3959
ME2 -1789 3526
ME3 4207 -3719
MPC1 -3681 -3235
MPC2 829 -1736
MT-CO1 -3167 -4114
MT-CYB -1355 -2353
MT-ND1 -353 -2211
MT-ND2 -1120 -2087
MT-ND4 -2086 -1594
MT-ND5 -3244 -2323
MT-ND6 816 -4592
NDUFA1 -737 311
NDUFA10 -1955 -3119
NDUFA11 -1033 -1135
NDUFA12 -1315 -659
NDUFA13 -2253 -2553
NDUFA2 -1290 -1978
NDUFA3 -3805 -593
NDUFA4 -393 -682
NDUFA5 534 -1670
NDUFA6 -77 -3389
NDUFA7 -465 -1825
NDUFA8 -602 -2505
NDUFA9 -2868 -2075
NDUFAB1 1151 -3257
NDUFAF1 1175 -4265
NDUFAF2 3504 -3248
NDUFAF3 -3581 -1264
NDUFAF4 3740 -2020
NDUFAF5 29 -977
NDUFAF6 -2555 -4096
NDUFAF7 2971 -457
NDUFB10 -3373 -2096
NDUFB11 -2103 -2860
NDUFB2 -3732 -962
NDUFB3 852 -1934
NDUFB4 -311 -1522
NDUFB5 -2039 -1176
NDUFB6 928 -307
NDUFB7 -4222 -1994
NDUFB8 -3020 -2917
NDUFB9 -996 -3435
NDUFC1 -664 -2904
NDUFC2 34 -2430
NDUFS1 -1544 -4374
NDUFS2 -3026 -2814
NDUFS3 -3567 -2753
NDUFS4 -1690 -2444
NDUFS5 -1235 -1924
NDUFS6 -1332 -980
NDUFS7 -4871 -1906
NDUFS8 -4325 -1999
NDUFV1 -4226 -2736
NDUFV3 -2378 -2590
NNT -3325 -2371
NUBPL -1541 -3546
OGDH -5268 -3650
PDHA1 -2405 -4451
PDHB -133 -3995
PDHX -126 -3872
PDK1 4600 -3234
PDK2 -5450 -3535
PDK3 4747 4864
PDK4 -712 -5238
PDP1 -2175 -4603
PDP2 -2619 -2438
PDPR -632 -4831
PPARD -4213 -2337
RXRA -5519 -4191
SCO1 3577 1708
SCO2 -1941 -772
SDHA -4773 -4591
SDHB 431 -3707
SDHC -3712 -3001
SLC16A1 -987 5075
SLC16A3 -4751 -4158
SLC25A14 3834 1871
SLC25A27 -2478 -4864
SUCLA2 1517 -4376
SUCLG1 -31 -2136
SUCLG2 -1167 -4291
SURF1 -1748 -4099
TACO1 651 -4262
TIMMDC1 213 -1107
TMEM126B 1024 1869
TRAP1 -5265 -2063
UCP2 -4949 5039
UCP3 -684 -5360
UQCR10 -3139 -259
UQCRB 403 -3715
UQCRC1 -3333 -3667
UQCRC2 551 -3907
UQCRFS1 -151 -3062
UQCRH -1532 -1753
UQCRQ -1767 -1856
VDAC1 -2909 -4606



Gene expression (Transcription)

Gene expression (Transcription)
metric value
setSize 997
pMANOVA 4.16e-18
p.adjustMANOVA 4.67e-16
s.dist 0.18
s.human 0.166
s.mouse 0.0706
p.human 4.98e-18
p.mouse 0.000237




Top 20 genes
Gene human mouse
ALYREF 5008 5231
TAF4B 4967 5209
CTR9 4954 5042
GTF2F1 4999 4919
CLP1 4787 5127
DDX21 4868 4778
TAF7 4717 4909
SUPT6H 4807 4811
ELL2 4753 4829
RYBP 4895 4575
EZH2 4698 4740
SIRT1 4935 4484
GTF2B 4276 5124
TAF1D 4278 5110
EAF1 4531 4808
GTF2A1 4730 4588
ZKSCAN5 4612 4688
NUP98 4235 5066
NFYA 4965 4269
CDK12 4852 4326

Click HERE to show all gene set members

All member genes
human mouse
AAAS -3476 1550.0
ABCA6 -135 -3028.0
ABL1 -4533 -3545.0
ACTB 940 4977.0
ACTL6A 4077 3325.0
AEBP2 3975 2675.0
AFF4 3610 1865.0
AGO1 2453 -2704.0
AGO2 -4001 -1788.0
AGO3 2529 -3975.0
AGO4 -3006 -3323.0
AIFM2 -4217 -2578.0
AKT1 -4954 342.0
AKT2 -4057 -4450.0
AKT3 1343 -320.0
ALYREF 5008 5231.0
ANAPC1 572 -4087.0
ANAPC10 1974 2134.0
ANAPC11 -3265 -1751.0
ANAPC15 -3393 1787.0
ANAPC16 -3612 -1148.0
ANAPC2 -2185 -3532.0
ANAPC4 -720 -4834.0
ANAPC5 1284 -2104.0
ANAPC7 1595 2349.0
APAF1 -3469 2921.0
APOE -1428 -89.0
AR -4468 -5288.0
ARID1A -1226 3491.0
ARID1B -3838 2336.0
ARID2 2812 -1805.0
ARID3A -4418 1310.0
ARID4B 4763 -2509.0
ASH2L -45 -3813.0
ASUN 1039 2317.0
ATAD2 4225 1685.0
ATF2 3130 1863.0
ATM 1449 -5067.0
ATP1B4 -5072 4958.0
ATR 1983 -63.0
ATXN3 4003 1472.0
AURKA 3811 325.0
AUTS2 -4742 3324.0
AXIN1 -730 3618.0
BANP 2381 3194.0
BAX -1846 4438.0
BAZ1B 3725 -2232.0
BAZ2A 4001 1701.0
BCDIN3D 1529 1933.0
BCL2L11 -4974 2480.0
BCL6 -5018 -4816.0
BDNF 1086 5114.0
BDP1 4285 -2624.0
BID -4951 3840.0
BLM 1103 4695.0
BMI1 3349 2265.0
BMP2 -4256 828.0
BNIP3L 3835 -1911.0
BRD1 -2076 508.0
BRD2 4330 3261.0
BRD7 221 -4649.0
BRF1 -5470 -662.0
BRF2 -1971 -2852.0
BRPF1 3074 3878.0
BRPF3 3668 4189.0
BTG1 3137 4645.0
BTG2 -5444 5224.0
CALM1 -4464 96.0
CAMK2A -5527 -4430.0
CAMK2B -5497 -4230.0
CAMK2D -2223 4137.0
CAMK2G -2097 -4962.0
CARM1 -4331 -4868.0
CASC3 9 1880.0
CASP1 -1298 3173.0
CASP2 2946 -3849.0
CASP6 4829 -2418.0
CAT -4828 -4266.0
CAV1 -646 -652.0
CBFB 3786 -4544.0
CBX2 2360 -1671.0
CBX4 3208 4863.0
CBX5 1538 -4637.0
CBX6 -482 912.0
CBX8 -917 -541.0
CCNA2 3061 4292.0
CCNC 4650 3537.0
CCND1 757 529.0
CCND2 225 405.0
CCND3 786 1371.0
CCNE1 4388 4753.0
CCNE2 4667 147.0
CCNG1 1596 -2074.0
CCNG2 -2635 -3814.0
CCNH 3825 -1657.0
CCNK 3139 154.0
CCNT1 4896 -1160.0
CCNT2 4381 -5015.0
CDC16 86 -1984.0
CDC23 3850 -1171.0
CDC26 2750 2457.0
CDC27 665 1230.0
CDC40 4670 4455.0
CDC7 2421 2065.0
CDC73 2659 -1467.0
CDK1 1580 3263.0
CDK12 4852 4326.0
CDK13 4123 1830.0
CDK2 849 2686.0
CDK4 703 3417.0
CDK5 -1007 -793.0
CDK6 1090 3036.0
CDK7 1571 -2032.0
CDK8 623 -1722.0
CDK9 -1348 4462.0
CDKN1A -4927 5092.0
CDKN1B -3284 -2450.0
CDKN2B -2827 2812.0
CEBPB -4699 1850.0
CENPJ 1720 -467.0
CHD3 -3721 -4142.0
CHD4 -4283 464.0
CHEK2 1311 1076.0
CHM 1406 -3917.0
CHTOP -574 2867.0
CITED2 770 5188.0
CITED4 -4657 -4817.0
CLDN5 -2058 2154.0
CLP1 4787 5127.0
CNOT1 4456 -3764.0
CNOT10 1314 -2770.0
CNOT11 2698 -468.0
CNOT2 3263 1266.0
CNOT3 857 3443.0
CNOT4 2350 2040.0
CNOT6 1509 2491.0
CNOT6L -2201 -298.0
CNOT7 1298 -926.0
CNOT8 3240 -1672.0
COL1A1 -1639 7.0
COX11 -2860 -1166.0
COX14 -2772 -4368.0
COX16 -2259 -1943.0
COX18 -554 635.0
COX19 3053 3493.0
COX20 1104 -2275.0
COX4I1 -2357 -1289.0
COX5A -2511 -2550.0
COX5B -2559 458.0
COX6A1 2259 2241.0
COX6B1 -2231 -855.0
COX6C -18 -845.0
COX7B 144 -729.0
COX7C -1495 -176.0
COX8A -4337 2642.0
CPSF1 -3670 1693.0
CPSF2 -922 1961.0
CPSF3 1953 -1.0
CPSF3L -1923 1572.0
CPSF4 862 4036.0
CPSF7 407 2081.0
CRADD -2847 -4600.0
CRCP 1806 -883.0
CREB1 2179 -4329.0
CREBBP 1506 3139.0
CSNK2A1 1796 -1733.0
CSNK2A2 2123 1393.0
CSNK2B 1917 -296.0
CSTF1 2216 2463.0
CSTF2 1437 -2189.0
CSTF2T 2703 4265.0
CSTF3 -2793 4044.0
CTDP1 2071 4335.0
CTGF -275 4426.0
CTNNB1 1714 -780.0
CTR9 4954 5042.0
CTSK 2 263.0
CTSV 2209 34.0
CUL1 -3121 -1536.0
DAXX 4449 4197.0
DDB2 -5027 -3332.0
DDIT3 -1718 243.0
DDIT4 -2764 4792.0
DDX21 4868 4778.0
DDX39A 3417 2816.0
DDX39B 984 2712.0
DEK 2056 4641.0
DGCR8 -4643 -12.0
DHX38 2857 -865.0
DICER1 1824 -4704.0
DLL1 -3980 -4227.0
DNA2 37 2385.0
DNMT1 -461 3606.0
DNMT3A -3771 -4732.0
DNMT3B -1360 -2620.0
DPY30 3923 275.0
DROSHA -694 -3097.0
DYRK2 -2000 -3920.0
E2F1 -529 4663.0
E2F4 -439 5017.0
E2F5 -249 2797.0
E2F6 650 -3768.0
E2F7 512 3338.0
E2F8 -5620 5126.0
EAF1 4531 4808.0
EED 3304 3671.0
EGFR 424 1475.0
EHMT1 -76 -2601.0
EHMT2 -520 -260.0
EIF4A3 4491 3824.0
ELF1 4399 3868.0
ELF2 -2817 -2798.0
ELL -3990 3019.0
ELL2 4753 4829.0
EP300 3403 -1622.0
EPC1 362 4066.0
ERBB2 -5511 673.0
ERCC2 824 2393.0
ERCC3 473 1570.0
ERCC6 4227 1247.0
ESR1 -1770 -3364.0
ESRRA -4570 -4245.0
ESRRB -2671 4031.0
ESRRG -4340 -4719.0
EZH2 4698 4740.0
FANCC -709 -459.0
FAS -4771 2899.0
FBXO32 -4380 -4921.0
FBXW7 -886 -330.0
FIP1L1 3587 1848.0
FKBP5 750 553.0
FOS 1865 5273.0
FOXO1 -432 1302.0
FOXO3 -42 -1131.0
FOXO4 -3493 -4492.0
FOXO6 -4157 -4011.0
FYTTD1 3374 4203.0
FZR1 -1244 3620.0
G6PD 579 4742.0
GADD45A 514 -1267.0
GAMT -5400 -5019.0
GATAD2A -975 4779.0
GATAD2B 304 3259.0
GLI2 -1180 3498.0
GLI3 3731 101.0
GLS 4937 -244.0
GPAM 1132 -5246.0
GPI -5210 -4132.0
GPS2 2002 3298.0
GSK3B 897 3200.0
GSR -2148 1119.0
GTF2A1 4730 4588.0
GTF2A2 4648 -1742.0
GTF2B 4276 5124.0
GTF2E1 2188 1803.0
GTF2E2 2041 120.0
GTF2F1 4999 4919.0
GTF2F2 4067 5069.0
GTF2H1 3886 1058.0
GTF2H2 4419 -2446.5
GTF2H3 -1925 467.0
GTF2H5 -878 -1711.0
GTF3A -2151 376.0
GTF3C1 4242 -1820.0
GTF3C3 -551 2992.0
GTF3C4 4066 973.0
GTF3C5 -2194 2163.0
GTF3C6 1008 1544.0
H2AFX 2356 5062.0
HDAC10 -3116 -2283.0
HDAC11 -4482 3956.0
HDAC2 4386 -1101.0
HDAC3 -178 -4320.0
HDAC4 -5061 -4325.0
HDAC5 -4921 2376.0
HDAC6 -4164 3925.0
HDAC7 -3827 -2596.0
HDAC8 209 -3381.0
HDAC9 -3759 2762.0
HES1 1695 -1766.0
HEY1 4826 451.0
HIPK1 4147 3646.0
HIPK2 -4312 -2060.0
HIVEP3 -179 4383.0
HSP90AA1 3656 5261.0
HSPD1 -855 -708.0
HTT -70 4380.0
HUS1 2435 -4471.0
IGFBP3 2922 -4847.0
ING2 3993 -1954.0
ING5 -2726 3394.0
INTS1 -1418 -2905.0
INTS10 4175 -4934.0
INTS12 3830 4418.0
INTS2 1193 1527.0
INTS3 1102 2904.0
INTS4 1878 1643.0
INTS5 1592 3677.0
INTS6 2200 4768.0
INTS7 2980 -1362.0
INTS8 1194 1805.0
INTS9 1494 4574.0
IPO8 -1526 -2775.0
IRAK1 -4351 -480.0
ITCH 4319 -2959.0
ITGA4 -2878 -5141.0
ITGA5 -4752 5178.0
ITGBL1 1885 -1676.0
IWS1 2510 1707.0
JAG1 3237 -2093.0
JARID2 2339 1172.0
JMY 3902 -2949.0
JUN 2469 5225.0
JUNB -2593 5221.0
KAT2A -5053 -1162.0
KAT2B -3340 -5260.0
KAT5 447 3955.0
KAT6A 3849 -725.0
KCTD1 -2989 1161.0
KCTD15 -3871 -4739.0
KCTD6 2748 3456.0
KDM5B 4870 2819.0
KLF4 3126 5024.0
KMT2A 4833 -157.0
KMT2C 4070 -3697.0
KMT2D -1176 -1807.0
KMT2E 3381 548.0
KRAS 3546 4454.0
KRBA1 -948 -5356.0
L3MBTL2 -956 3155.0
LAMTOR1 -800 -2671.0
LAMTOR2 -1715 -424.0
LAMTOR3 3134 3162.0
LAMTOR4 -2977 2289.0
LAMTOR5 636 -324.0
LBR 2244 -1398.0
LDB1 -5369 -2642.0
LEO1 2784 2307.0
LGALS3 1062 4809.0
LIFR -994 -4795.0
LMO2 -1725 2311.0
LRPPRC 1656 -4390.0
LSM10 -3826 1565.0
LSM11 -2895 465.0
MAF -5349 -5312.0
MAGOH 4561 4010.0
MAGOHB 2239 2185.0
MAML1 2770 4603.0
MAML2 2681 640.0
MAML3 -2079 -345.0
MAMLD1 -1668 1073.0
MAP2K6 1456 -4876.0
MAPK1 1988 -648.0
MAPK11 -3385 -333.0
MAPK14 -1562 -1635.0
MAPK3 -1024 3725.0
MAPKAP1 -405 2624.0
MAX -2352 1069.0
MBD2 3965 1159.0
MBD3 -3419 1364.0
MDC1 841 2997.0
MDM2 3253 3321.0
MDM4 2051 -4809.0
MEAF6 1066 1292.0
MECP2 -1705 -4130.0
MED1 4772 -2976.0
MED10 4087 2651.0
MED12 -2130 -2791.0
MED13 4601 4442.0
MED14 2781 -4663.0
MED15 1233 4823.0
MED16 -2476 -4328.0
MED17 4255 676.0
MED20 3604 -3993.0
MED23 3909 2513.0
MED24 -4786 -4086.0
MED25 2948 1925.0
MED26 4038 2036.0
MED27 1227 3689.0
MED30 2307 -28.0
MED31 4638 377.0
MED4 4026 4309.0
MED6 4813 2205.0
MED7 4316 2498.0
MED8 4163 -215.0
MEF2C -4610 -2794.0
MEN1 1348 2492.0
MET -3529 2929.0
MGA 4502 -4742.0
MLH1 -1210 -4562.0
MLLT1 472 1878.0
MLLT3 3202 3787.0
MLST8 -3485 -2266.0
MNAT1 830 -2433.0
MOV10 -4127 1367.0
MSH2 4647 -5020.0
MSTN -3974 4425.0
MT-CO1 -3167 -4114.0
MTA1 -4102 4542.0
MTA2 3682 946.0
MTA3 -2123 -1614.0
MTF2 4304 763.0
MTOR -1191 -1922.0
MYBBP1A -833 3169.0
MYC 3994 4886.0
MYL9 -4777 11.0
MYO1C -4842 3521.0
NABP1 -3908 5015.0
NABP2 -279 -1673.0
NBN 1286 -1205.0
NCBP1 -1736 4182.0
NCBP2 4188 264.0
NCOR1 2625 -3925.0
NCOR2 -5167 -1521.0
NDC1 1273 -2350.0
NDRG1 -102 650.0
NDUFA4 -393 -682.0
NEDD4L 4279 -2158.0
NELFA 356 3929.0
NELFB -1196 2773.0
NELFCD 1896 -2294.0
NELFE -2178 3334.0
NFATC2 -3264 3355.0
NFIA -4269 -76.0
NFIB 267 -2369.0
NFIC -5402 -4106.0
NFIX -5330 -4257.0
NFKB1 -4233 3315.0
NFYA 4965 4269.0
NFYB 1632 -3915.0
NFYC -1444 -1181.0
NOC2L 1374 1201.0
NOP2 3472 4824.0
NOTCH1 -5460 44.0
NOTCH3 -1225 773.0
NR1D1 -5185 -985.0
NR1D2 1828 -5211.0
NR1H2 2288 3553.0
NR1H3 -3630 -3237.0
NR2C1 679 -897.0
NR2C2 1579 -4371.0
NR2C2AP 2640 2663.0
NR2F1 -4439 1268.0
NR2F6 -4543 2556.0
NR3C1 985 -4192.0
NR3C2 -1723 -18.0
NR4A1 -5560 -642.0
NR4A2 -1651 4423.0
NR4A3 -4264 4712.0
NR6A1 -2345 2302.0
NRBF2 4966 -2441.0
NRBP1 2753 3576.0
NUAK1 -2765 86.0
NUDT21 3626 3457.0
NUP107 3232 2949.0
NUP133 889 -4048.0
NUP153 4762 1533.0
NUP155 4306 -2233.0
NUP160 3998 1035.0
NUP188 2117 3830.0
NUP205 4438 3588.0
NUP214 3124 665.0
NUP35 4571 649.0
NUP37 -327 192.0
NUP43 4562 2216.0
NUP54 4508 3831.0
NUP85 3181 -393.0
NUP88 1244 2212.0
NUP93 -1503 3903.0
NUP98 4235 5066.0
PAF1 2516 -2180.0
PARP1 -2423 -2631.0
PBRM1 3523 -4706.0
PCBP4 -5523 -1872.0
PCF11 -1597 -2897.0
PCGF5 1470 586.0
PCGF6 1159 2779.0
PCNA 1329 5082.0
PDPK1 3443 2222.0
PERP 831 -2655.0
PHAX 4729 840.0
PHC1 456 -1955.0
PHC2 -3719 4976.0
PHC3 3141 -3012.0
PHF1 -1798 3270.0
PHF19 -2605 1929.0
PHF20 819 -2632.0
PIN1 -3515 1213.0
PINK1 -4060 -3052.0
PIP4K2A 4108 4491.0
PIP4K2C 2827 2664.0
PITX2 -5256 -35.0
PIWIL2 773 -1813.0
PLAGL1 -4577 3731.0
PLK2 4764 4365.0
PLK3 -1003 4968.0
PLXNA4 -319 -842.0
PMAIP1 -4203 5154.0
PML 3338 3449.0
PMS2 806 -1784.0
POLDIP3 -1320 4692.0
POLR1A -2441 -3658.0
POLR1B 3644 -995.0
POLR1C 3643 4119.0
POLR1D 413 1462.0
POLR1E 2918 3405.0
POLR2A 3861 5046.0
POLR2B 4509 -4119.0
POLR2C 4529 -904.0
POLR2D 1669 2692.0
POLR2E -667 1599.0
POLR2G 89 5112.0
POLR2H -3927 3497.0
POLR2I -154 81.0
POLR2K 2480 -1584.0
POLR2L -4314 4110.0
POLR3A 4348 -4076.0
POLR3B 2547 -3390.0
POLR3C 4052 3012.0
POLR3D 381 1468.0
POLR3E 1908 -1229.0
POLR3F 4054 2443.0
POLR3G 1455 3367.0
POLR3GL -1424 -3192.0
POLR3H 282 2294.0
POLR3K 4716 -3105.0
POLRMT -2205 -2381.0
POU2F1 3019 -3333.0
POU4F1 -1640 -4107.0
PPARA -4997 -4570.0
PPARD -4213 -2337.0
PPARG -1621 -2269.0
PPARGC1A -4212 -5006.0
PPARGC1B -5257 -4147.0
PPM1A 3438 -2366.0
PPM1D 1792 2505.0
PPP1R13B 3413 770.0
PPP1R13L -3554 3890.0
PPP2CA 4482 3008.0
PPP2CB 2458 4129.0
PPP2R1A -4013 -696.0
PPP2R1B 3028 4619.0
PPP2R5C -2508 -3684.0
PRDM1 -50 -4776.0
PRDX1 605 1340.0
PRDX2 -5293 -2557.0
PRDX5 -3356 -1867.0
PRELID1 1651 4804.0
PRKAA1 3389 2810.0
PRKAA2 -3219 -5163.0
PRKAB1 3436 1814.0
PRKAB2 -2332 -2820.0
PRKACA -4691 -1606.0
PRKAG1 2103 -1806.0
PRKAG2 -3237 -3533.0
PRKAG3 -5537 -5285.0
PRKCQ -5095 -4882.0
PRKRA 1984 -1578.0
PRMT5 933 1373.0
PRMT6 2063 4522.0
PRR5 -837 422.0
PSMA1 2820 3328.0
PSMA3 3434 -4.0
PSMA4 769 958.0
PSMA6 2199 -1044.0
PSMA7 -2980 976.0
PSMB1 954 2628.0
PSMB10 -1800 2907.0
PSMB2 618 2471.0
PSMB4 -235 2096.0
PSMB5 -4113 -606.0
PSMB6 -793 914.0
PSMB7 -831 -1453.0
PSMB8 -675 2066.0
PSMB9 -1611 -2973.0
PSMC1 449 -336.0
PSMC2 -1311 3241.0
PSMC3 -2439 -369.0
PSMC4 2724 1416.0
PSMC5 1212 -1123.0
PSMC6 -2520 3423.0
PSMD1 2619 -1191.0
PSMD10 -1227 525.0
PSMD11 995 5183.0
PSMD12 3831 536.0
PSMD13 821 1665.0
PSMD14 -635 3816.0
PSMD2 -713 -555.0
PSMD3 -3343 2226.0
PSMD4 -214 2558.0
PSMD5 1807 3558.0
PSMD6 3537 -2207.0
PSMD7 -2329 1233.0
PSMD8 -3171 4626.0
PSMD9 4204 -970.0
PSME1 -2771 3350.0
PSME2 -4085 3584.0
PSME3 3333 3379.0
PSME4 1960 -4574.0
PSMF1 683 -1480.0
PTEN 2797 2721.0
PTPN1 1531 4585.0
PTPN11 -1575 -666.0
PTPN4 -1408 3737.0
PTRF -3348 3621.0
RABGGTA -1231 -2531.0
RABGGTB -945 568.0
RAD1 3205 3561.0
RAD17 2273 808.0
RAD50 306 -3473.0
RAD51 63 -2396.0
RAD51D -876 -2147.0
RAD9A -3149 -154.0
RAE1 4471 2389.0
RAN 2329 1938.0
RANBP2 4470 -3848.0
RARA -5250 2741.0
RARB -2995 -2000.0
RARG -4431 -4039.0
RB1 -2449 1464.0
RBBP4 1072 2469.0
RBBP5 4628 41.0
RBBP7 -924 -2291.0
RBBP8 3047 3316.0
RBFOX1 -5102 -4462.0
RBL1 -1617 778.0
RBL2 -242 -5105.0
RBM14 4731 4087.0
RBPJ 305 4930.0
RBX1 -733 -968.0
RELA 1783 4531.0
RFC2 622 -1170.0
RFC3 2151 4113.0
RFC4 3542 964.0
RFC5 1409 3528.0
RFFL 1079 -1551.0
RGCC -1145 5234.0
RHEB 172 2951.0
RHNO1 -4573 -113.0
RICTOR 3562 -2934.0
RING1 -1968 -125.0
RMI1 4517 -56.0
RMI2 -2759 -5106.0
RNF111 3964 4756.0
RNF2 3038 4651.0
RNF34 3719 -1122.0
RNGTT 4414 1057.0
RNMT 4864 -807.0
RNPS1 681 -379.0
RORA -5056 -2699.0
RORC -5248 -4317.0
RPA1 -1837 -4231.0
RPA2 2889 -1373.0
RPA3 2702 -1706.0
RPAP2 3147 -3300.0
RPRD1A -3380 -3404.0
RPRD1B 2187 -1926.0
RPRD2 4039 -351.0
RPS27A 783 1840.0
RPTOR -4596 2076.0
RQCD1 4265 347.0
RRAGA 2383 4477.0
RRAGB -366 -548.0
RRAGC 2091 945.0
RRAGD -4673 -5179.0
RRM2B -887 -4977.0
RRN3 4557 1545.0
RRP8 4411 1769.0
RTF1 -2993 -2893.0
RUNX1 -2434 4962.0
RUNX2 85 1728.0
RXRA -5519 -4191.0
RXRB -1250 -3372.0
RXRG -4055 1680.0
RYBP 4895 4575.0
SAP130 3375 3793.0
SAP18 4832 915.0
SAP30 138 3376.0
SAP30BP 823 5055.0
SAP30L -2519 -2355.0
SARNP 569 48.0
SATB2 3702 5210.0
SCMH1 -5007 -1597.0
SCO1 3577 1708.0
SCO2 -1941 -772.0
SEC13 730 1702.0
SEH1L 1085 4263.0
SERPINE1 -211 5168.0
SESN1 -4227 3713.0
SESN2 -2604 5137.0
SESN3 4513 -2160.0
SETD1A 2076 2948.0
SETD1B -3010 2327.0
SF3B1 1067 3140.0
SGK1 1084 -5256.0
SIN3A 3397 267.0
SIN3B 1030 2716.0
SIRT1 4935 4484.0
SIRT3 -2752 -5206.0
SKI -3187 1297.0
SKIL 1818 1156.0
SKP1 2028 -2504.0
SKP2 4205 4385.0
SLBP 2666 4952.0
SLC2A3 5004 2971.5
SLC38A9 969 -2953.0
SLU7 4893 3614.0
SMAD1 -2920 5081.0
SMAD2 1125 4898.0
SMAD3 -3794 -5343.0
SMAD4 2354 -52.0
SMAD6 2009 -2772.0
SMAD7 -1051 1964.0
SMARCA2 -2904 -5150.0
SMARCA4 -3874 -1402.0
SMARCA5 4439 2255.0
SMARCB1 -474 3240.0
SMARCC1 -4311 -2069.0
SMARCC2 -3726 -493.0
SMARCD1 2718 2939.0
SMARCD2 319 937.0
SMARCD3 -5399 -4597.0
SMARCE1 1364 3960.0
SMURF1 4443 2060.0
SMURF2 1070 4724.0
SMYD2 -1305 -5129.0
SNAPC1 3749 4880.0
SNAPC2 3411 899.0
SNAPC3 3029 -1441.0
SNAPC4 363 -1786.0
SNAPC5 -703 -1692.0
SNRPB 3761 35.0
SNRPD3 2384 -1603.0
SNRPE 3421 760.0
SNRPF 3777 2400.0
SNRPG 3179 3615.0
SNW1 3618 4819.0
SOCS3 -283 5103.0
SOCS4 4713 2490.0
SOD2 -1568 -3943.0
SOX9 2175 5159.0
SP1 1787 -1016.0
SPP1 1162 3043.0
SRC -3910 1378.0
SREBF1 -5230 594.0
SRRM1 2285 -746.0
SRRT 4962 3050.0
SRSF1 1871 -429.0
SRSF11 3911 -4703.0
SRSF3 2586 3185.0
SRSF4 1929 4093.0
SRSF5 1997 -2886.0
SRSF6 1798 3296.0
SRSF7 3545 4305.0
SRSF9 3543 3246.0
SSB 4371 4547.0
SSRP1 1755 3948.0
SSU72 1324 -300.0
STAT1 236 -1738.0
STEAP3 -5586 -4653.0
STK11 -4884 -2152.0
STUB1 -2898 -690.0
SUDS3 3840 -2057.0
SUMO1 4213 1399.0
SUPT16H 3885 4363.0
SUPT4H1 3648 -1203.0
SUPT5H 1321 3508.0
SUPT6H 4807 4811.0
SURF1 -1748 -4099.0
SUV39H1 576 -1202.0
SUZ12 3871 1927.0
SYMPK -3207 -2811.0
TACO1 651 -4262.0
TAF1 1708 -350.0
TAF10 -273 2957.0
TAF11 2962 -484.0
TAF12 3100 3164.0
TAF13 4749 1567.0
TAF1A 2375 -1076.0
TAF1B 3690 1901.0
TAF1C -1934 3297.0
TAF1D 4278 5110.0
TAF2 4591 3381.0
TAF3 4294 4474.0
TAF4 -1340 3063.0
TAF4B 4967 5209.0
TAF5 4309 2830.0
TAF6 -912 55.0
TAF7 4717 4909.0
TAF8 2937 1691.0
TAF9B 1874 519.0
TARBP2 1653 -841.0
TBL1XR1 1876 -2165.0
TBP 1137 2611.0
TCEA1 4037 647.0
TCF12 1614 4124.0
TCF3 -2289 2184.0
TCF7 1204 2448.0
TCF7L1 -3205 2935.0
TCF7L2 -74 -1755.0
TDG 3925 3339.0
TDRKH 567 -2031.0
TEAD1 -4292 -1880.0
TEAD2 323 -142.0
TEAD3 -4846 -3020.0
TEAD4 -5380 -3156.0
TET1 3219 -5217.0
TET2 1688 -2614.0
TET3 1591 -1395.0
TFAM 4351 -1865.0
TFB2M 4922 -4768.0
TFDP1 -2245 -2659.0
TFDP2 4029 -5361.0
TGFB1 -3111 4943.0
TGIF1 -2131 3663.0
THBS1 762 4431.0
THOC1 2868 2547.0
THOC2 4510 -4472.0
THOC3 2831 -1702.0
THOC5 4842 542.0
THOC6 -904 3700.0
THOC7 -873 -3339.0
THRA -5483 -5283.0
THRB -1313 -4788.0
TJP1 405 -3133.0
TMEM219 -3222 -1406.0
TMEM55B 3859 2821.0
TNFRSF10A -3936 1259.5
TNFRSF10B -1612 1259.5
TNFRSF10C -2321 1259.5
TNFRSF10D -3227 1259.5
TNKS1BP1 -4407 1783.0
TNRC6A 3585 -573.0
TNRC6B 3118 -4527.0
TNRC6C -2020 -1918.0
TOP3A 2607 1632.0
TOPBP1 2183 4567.0
TP53 575 3751.0
TP53BP2 4687 2493.0
TP53INP1 -2309 -3743.0
TP53RK 3992 1448.0
TP63 3691 -337.0
TPR 2984 -1026.0
TPX2 3446 2359.0
TRIAP1 901 881.0
TRIM28 4209 4460.0
TRIM33 2796 2074.0
TRIM63 -4866 -2132.0
TSC1 2577 -2625.0
TSC2 -4999 -1090.0
TSN 2947 -4542.0
TTC5 3302 82.0
TTF1 4368 -488.0
TWIST1 2624 2962.0
TXN 1855 4791.0
TXNRD1 -2444 2445.0
U2AF2 4337 3060.0
UBC 2672 4480.0
UBE2C 4949 463.0
UBE2D1 -1588 -4032.0
UBE2D3 1424 4934.0
UBE2E1 -1132 -479.0
UBE2I 1246 1214.0
UBE2S 4441 4268.0
UPF3B 1586 -4316.0
USP2 -5039 -2958.0
USP7 3857 277.0
USP9X 1458 -4487.0
UXT -248 1342.0
VEGFA -4571 -5196.0
VWA9 2598 73.0
WDR33 3143 1005.0
WDR5 -1608 1773.0
WDR61 -1148 301.0
WRN 98 2665.0
WWOX 1055 -3182.0
WWP1 -1200 -5241.0
WWTR1 -2503 809.0
XPO5 2131 -2928.0
YAF2 182 -1698.0
YAP1 -476 3863.0
YEATS4 3247 4452.0
YES1 -176 -2941.0
YWHAB 3680 3415.0
YWHAE 1394 -914.0
YWHAG -2372 -3104.0
YWHAH -2777 4700.0
YWHAQ 963 3739.0
YWHAZ 2019 4495.0
ZC3H8 -3996 -3720.0
ZFHX3 -2823 -1477.0
ZFP1 777 1054.0
ZFP14 -1564 -2258.0
ZFP2 -2603 -3327.0
ZFP28 4189 -1082.0
ZFP30 516 -3758.0
ZFP37 4076 4532.0
ZFP69 3315 885.0
ZFP90 480 1431.0
ZFPM1 71 1174.0
ZIK1 4897 -4577.0
ZKSCAN1 -1405 2369.0
ZKSCAN3 630 -4083.5
ZKSCAN4 4031 -4083.5
ZKSCAN5 4612 4688.0
ZKSCAN7 -1769 -4260.0
ZKSCAN8 3190 -5273.0
ZNF101 4947 -3935.0
ZNF112 2487 -1819.0
ZNF12 2721 -2788.0
ZNF124 4126 -3935.0
ZNF143 1822 4417.0
ZNF169 -1838 -95.0
ZNF18 3432 3441.0
ZNF180 3868 -1454.0
ZNF189 1916 -3063.0
ZNF202 2190 2960.0
ZNF205 -2430 1761.0
ZNF212 554 651.0
ZNF213 -509 695.0
ZNF23 1671 -3290.0
ZNF235 2757 -5191.0
ZNF248 -2815 494.0
ZNF25 -3296 4123.0
ZNF250 -514 -194.0
ZNF263 4581 1183.0
ZNF274 4186 -4975.0
ZNF282 -3935 1751.0
ZNF286A 3048 -2213.0
ZNF287 3780 -3286.0
ZNF3 3939 -3789.0
ZNF317 3402 513.0
ZNF324 2644 130.5
ZNF324B 2800 130.5
ZNF334 961 3548.0
ZNF347 4334 -4237.5
ZNF354A 4577 -2881.0
ZNF354C 1442 -3786.0
ZNF385A -5211 4005.0
ZNF394 4721 -950.0
ZNF398 1779 1470.0
ZNF416 4497 197.0
ZNF420 16 2432.0
ZNF426 3687 378.0
ZNF429 -5017 -4708.5
ZNF43 4092 -4836.5
ZNF436 3688 -3750.0
ZNF445 -3447 -5082.0
ZNF446 -63 -3109.0
ZNF45 4715 -3085.0
ZNF454 921 -797.0
ZNF493 -3572 -4836.5
ZNF496 -2663 -213.0
ZNF521 629 312.0
ZNF551 4427 -1225.0
ZNF559 4814 -3313.5
ZNF560 3600 2855.0
ZNF561 -185 -2672.5
ZNF562 -55 -2672.5
ZNF566 549 996.0
ZNF569 2722 -3079.0
ZNF585A 4317 -3769.0
ZNF597 3559 -1334.0
ZNF606 1719 -4100.0
ZNF641 -4105 -2397.0
ZNF655 1508 4322.0
ZNF660 -856 -3726.0
ZNF664 -1330 1122.0
ZNF665 359 -4237.5
ZNF667 1646 -1140.0
ZNF668 3548 1490.0
ZNF669 4901 -3935.0
ZNF678 3662 -4615.0
ZNF688 -1703 3477.0
ZNF689 2277 3161.0
ZNF691 1491 -4306.0
ZNF692 -475 -2970.0
ZNF697 -787 4655.0
ZNF703 -5506 -3188.0
ZNF704 -3376 -1530.0
ZNF706 99 -2036.0
ZNF707 -1032 2031.0
ZNF710 -2142 -4869.0
ZNF720 4946 -5268.5
ZNF721 4971 -3955.5
ZNF738 4987 -5268.5
ZNF740 -4838 -3657.0
ZNF746 736 1942.0
ZNF764 -1896 3106.0
ZNF770 4367 -4912.0
ZNF771 107 1997.0
ZNF775 -3056 -2600.0
ZNF777 657 736.0
ZNF790 -3148 -2282.0
ZNF791 4620 -1735.0
ZNF839 -808 -82.0
ZSCAN25 2848 1801.0



Metabolism

Metabolism
metric value
setSize 1377
pMANOVA 1.63e-15
p.adjustMANOVA 1.67e-13
s.dist 0.148
s.human -0.115
s.mouse -0.0931
p.human 4.7e-12
p.mouse 2.29e-08




Top 20 genes
Gene human mouse
CARNS1 -5545 -5372
PHKG1 -5495 -5329
IP6K3 -5500 -5300
MMAB -5378 -5342
AMPD1 -5321 -5352
ACOT11 -5260 -5320
GPT -5145 -5355
GAMT -5400 -5019
ACACB -5376 -4996
GMPR -5365 -4999
AK1 -5327 -5034
D2HGDH -4890 -5334
KCNB1 -5117 -5063
SLC44A2 -5438 -4740
GBA2 -5138 -4972
ABCD1 -5486 -4643
PLIN3 -5023 -5040
AGL -4967 -5094
PYGM -5462 -4619
SLC27A1 -5082 -4960

Click HERE to show all gene set members

All member genes
human mouse
AAAS -3476.0 1550.0
AACS -2824.0 4467.0
AASDHPPT 2437.0 -2491.0
ABCA1 1045.0 -4559.0
ABCB7 2119.0 -4950.0
ABCC1 1074.0 -2005.0
ABCC3 -265.0 3097.0
ABCC5 1609.0 -4550.0
ABCD1 -5486.0 -4643.0
ABCD4 477.0 -3574.0
ABCG2 -2465.0 4953.0
ABHD10 -834.0 -2894.0
ABHD14B -3299.0 -4835.0
ABHD3 -81.0 5120.0
ABHD4 -3273.0 188.0
ABHD5 2522.0 -3728.0
ACAA2 -2330.0 -4994.0
ACACB -5376.0 -4996.0
ACAD10 -4565.0 -4895.0
ACAD11 421.0 -4580.0
ACAD8 -1259.0 -5038.0
ACAD9 -4578.0 -4558.0
ACADL -1021.0 -3930.0
ACADM -1714.0 -4540.0
ACADS -4663.0 -3992.0
ACADSB 3088.0 -4936.0
ACADVL -4952.0 -4299.0
ACAT1 470.0 -1935.0
ACAT2 -2653.0 -3725.0
ACBD4 -2075.0 -4507.0
ACBD5 -1208.0 -4446.0
ACER2 -197.0 4875.0
ACER3 -3365.0 2582.0
ACHE -4785.0 -3215.0
ACLY -2628.0 3492.0
ACO2 -3822.0 -4426.0
ACOT1 1587.0 -5151.5
ACOT11 -5260.0 -5320.0
ACOT13 -2994.0 -3100.0
ACOT2 -2912.0 -5151.5
ACOT7 -716.0 3041.0
ACOT8 -957.0 423.0
ACOT9 478.0 4970.0
ACOX1 3989.0 3691.0
ACOX3 -2027.0 -4189.0
ACP6 -3801.0 -879.0
ACSF2 -5148.0 1463.0
ACSF3 -4301.0 -4632.0
ACSL1 -3367.0 -2365.0
ACSL3 3465.0 3232.0
ACSL4 481.0 -1616.0
ACSS2 -5297.0 -4186.0
ACSS3 1498.0 2924.0
ADA -2382.0 3136.0
ADAL 625.0 -5182.0
ADCY1 -3780.0 -1927.0
ADCY2 -4820.0 -3731.0
ADCY3 338.0 187.0
ADCY5 1967.0 1780.0
ADCY6 -4515.0 -4206.0
ADCY7 -2820.0 2292.0
ADCY9 -4889.0 -4292.0
ADH5 2755.0 -3587.0
ADHFE1 -4039.0 -2474.0
ADI1 -2375.0 -4839.0
ADIPOR1 929.0 -817.0
ADIPOR2 3220.0 1397.0
ADK -1624.0 -2492.0
ADO 3203.0 -2720.0
ADPGK 5005.0 5072.0
ADPRM 2616.0 -3602.0
ADRA2A -4661.0 -1779.0
ADSL -3606.0 -4557.0
ADSS 1913.0 -1315.0
ADSSL1 -5209.0 -3445.0
AFMID -4778.0 -1281.0
AGK -3597.0 -1970.0
AGL -4967.0 -5094.0
AGPAT1 -1154.0 57.0
AGPAT2 -4979.0 -2002.0
AGPAT3 -4732.0 -3460.0
AGPAT4 -4548.0 4992.0
AGPAT5 513.0 432.0
AGPS 3505.0 -1239.0
AGRN -4903.0 -2954.0
AGT -4723.0 -621.0
AHCY -4149.0 4640.0
AHCYL1 -3386.0 988.0
AHR 4872.0 805.0
AIMP1 1421.0 -872.0
AIMP2 -2727.0 -2611.0
AIP -707.0 -1563.0
AK1 -5327.0 -5034.0
AK2 -2781.0 832.0
AK4 4501.0 1993.0
AKR1A1 -2363.0 1114.0
AKR1B1 -3280.0 4770.0
AKR1B10 2786.0 3860.5
AKR1B15 -4492.0 3860.5
AKT1 -4954.0 342.0
ALAD -3855.0 -3630.0
ALAS1 3230.0 -4716.0
ALDH18A1 890.0 5074.0
ALDH1A1 -3063.0 -3787.0
ALDH1L2 872.0 -4160.0
ALDH2 -1511.0 -4683.0
ALDH3A2 -71.0 -1276.0
ALDH3B1 -4529.0 4142.0
ALDH4A1 -2303.0 -3465.0
ALDH6A1 -1396.0 -5239.0
ALDH7A1 -1797.0 -4159.0
ALDH9A1 2869.0 1220.0
ALDOA -5575.0 -3482.0
ALDOC 1379.0 4707.0
AMACR 4160.0 -4052.0
AMD1 4853.0 -3622.0
AMPD1 -5321.0 -5352.0
AMPD2 -3317.0 3302.0
AMPD3 -4286.0 4079.0
ANGPTL4 -739.0 2496.0
ANKRD1 1306.0 5211.0
AOC2 1475.0 3374.0
AOC3 118.0 -216.0
AOX1 1453.0 -5248.0
APIP 2668.0 4521.0
APOE -1428.0 -89.0
APRT -3384.0 -51.0
ARF1 566.0 4500.0
ARF3 4654.0 4624.0
ARNT 3334.0 468.0
ARNT2 -2168.0 -3159.0
ARNTL 1256.0 4825.0
ARSA -3312.0 1530.0
ARSB -1001.0 2832.0
ARSG -3357.0 -116.0
ARSI -1498.0 2661.0
ARSK 3266.0 -3292.0
ARV1 -3314.0 319.0
ASAH1 -3414.0 5051.0
ASAH2 2603.0 -5131.5
ASL 653.0 2838.0
ASNS 2808.0 3601.0
ASPA -2360.0 -2347.0
ASRGL1 674.0 -4300.0
ASS1 -5412.0 4855.0
ATIC 7.0 2709.0
AUH -1294.0 -3181.0
AZIN1 -183.0 5227.0
B3GALNT1 67.0 3135.0
B3GALT1 -3699.0 -1219.0
B3GALT2 -4090.0 -1182.0
B3GALT4 -2720.0 -2534.0
B3GALT6 -1251.0 4136.0
B3GAT3 -4234.0 1339.0
B4GALNT1 -3532.0 4983.0
B4GALT1 -1314.0 2589.0
B4GALT2 -5041.0 2217.0
B4GALT3 974.0 1167.0
B4GALT4 1641.0 -701.0
B4GALT5 -4066.0 4166.0
B4GALT6 2704.0 3082.0
B4GALT7 -4152.0 -1537.0
BCAT1 -3549.0 4056.0
BCAT2 -4182.0 -4959.0
BCHE 364.0 -1103.0
BCKDHB -4241.0 -2630.0
BCKDK -4693.0 -3624.0
BDH1 -4435.0 -3851.0
BDH2 -1922.0 3427.0
BGN -1474.0 3919.0
BLVRA -1795.0 248.0
BLVRB -5052.0 956.0
BPGM 3356.0 -3625.0
BPHL -3183.0 -3384.0
BPNT1 4825.0 -3425.0
BSG -2248.0 -2113.0
BTD 2566.0 2195.0
CA2 4980.0 -302.0
CA3 -4097.0 -5030.0
CA5B -72.0 2695.0
CA7 -2940.0 -5066.0
CACNA1A -1249.0 -1680.0
CACNA1C -762.0 -668.0
CACNB3 149.0 -3506.0
CAD -2572.0 1095.0
CALM1 -4464.0 96.0
CARM1 -4331.0 -4868.0
CARNS1 -5545.0 -5372.0
CAV1 -646.0 -652.0
CBR3 297.0 1454.0
CBR4 3854.0 -4705.0
CCNC 4650.0 3537.0
CD320 -2432.0 -726.0
CD36 -582.0 -3838.0
CD44 837.0 4987.0
CDIPT 2222.0 -2824.0
CDK19 3157.0 -3958.0
CDK8 623.0 -1722.0
CDO1 2038.0 2570.0
CDS1 4830.0 -2683.0
CDS2 -5090.0 1323.0
CEPT1 53.0 241.0
CERK -4082.0 2856.0
CERS1 -4077.0 -3406.0
CERS2 -2095.0 2078.0
CERS5 2032.0 -365.0
CERS6 -4819.0 4220.0
CES2 -5628.0 1982.0
CHAC1 2903.0 -2432.0
CHAC2 3701.0 -2012.0
CHD9 3127.0 -1910.0
CHKA 765.0 4979.0
CHP1 -496.0 1845.0
CHPF -4447.0 1251.0
CHPF2 -2067.0 2386.0
CHPT1 3501.0 -4965.0
CHST11 -184.0 2277.0
CHST12 -1265.0 1278.0
CHST14 -3829.0 1240.0
CHST15 -4700.0 -3213.0
CHST2 2436.0 1672.0
CHST3 -4526.0 4276.0
CHST7 2731.0 -1325.0
CHSY1 3804.0 1910.0
CIAO1 -4183.0 -3066.0
CIAPIN1 4155.0 -1639.0
CIDEC -4843.0 -3207.0
CKB -5304.0 3435.0
CKM -4625.0 -3863.0
CKMT2 -3814.0 -3094.0
CLOCK -1534.0 139.0
CMBL -4971.0 -4235.0
CMPK1 2089.0 4806.0
CNDP2 -2176.0 4503.0
COASY 3072.0 -40.0
COMT -5098.0 -1696.0
COQ10A -3553.0 -2653.0
COQ10B 4344.0 4255.0
COQ2 -1700.0 -2051.0
COQ3 1225.0 -4296.0
COQ5 -3730.0 -5061.0
COQ6 232.0 -2212.0
COQ7 -3047.0 -2411.0
COQ9 -4501.0 -4432.0
COX10 2735.0 -3718.0
COX11 -2860.0 -1166.0
COX14 -2772.0 -4368.0
COX15 571.0 -5210.0
COX16 -2259.0 -1943.0
COX18 -554.0 635.0
COX19 3053.0 3493.0
COX20 1104.0 -2275.0
COX4I1 -2357.0 -1289.0
COX5A -2511.0 -2550.0
COX5B -2559.0 458.0
COX6A1 2259.0 2241.0
COX6B1 -2231.0 -855.0
COX6C -18.0 -845.0
COX7B 144.0 -729.0
COX7C -1495.0 -176.0
COX8A -4337.0 2642.0
CPNE3 1228.0 -3452.0
CPOX -865.0 -3572.0
CPT1A -357.0 330.0
CPT2 555.0 -5292.0
CRAT -5334.0 -3418.0
CREBBP 1506.0 3139.0
CRLS1 -1542.0 63.0
CROT 3694.0 5089.0
CRYL1 -3923.0 -403.0
CS 3653.0 -3566.0
CSAD -2141.0 -2621.0
CSGALNACT1 -205.0 2561.0
CSGALNACT2 1507.0 4035.0
CSNK1G2 -1933.0 -1532.0
CSNK2A1 1796.0 -1733.0
CSNK2A2 2123.0 1393.0
CSNK2B 1917.0 -296.0
CSPG4 -5621.0 538.0
CTH 4099.0 1072.0
CTPS1 3837.0 3187.0
CTPS2 -2992.0 -3145.0
CTSA -3537.0 -2181.0
CYB5A -1123.0 -2299.0
CYB5B 621.0 -4193.0
CYB5R3 -5395.0 3330.0
CYC1 -4147.0 -4031.0
CYGB -3091.0 1362.0
CYP26B1 -756.0 -2217.0
CYP27A1 -4508.0 -5335.0
CYP2E1 -1403.0 -1567.0
CYP2J2 -5037.0 -3041.0
CYP2U1 -3305.0 -2764.0
CYP39A1 1668.0 -1258.0
CYP4V2 -2707.0 523.0
CYP51A1 -1716.0 5047.0
D2HGDH -4890.0 -5334.0
DBI -2859.0 4399.0
DBT 2001.0 5208.0
DCK -511.0 4534.0
DCN -1048.0 -896.0
DCTD -3586.0 2150.0
DCTPP1 2817.0 1714.0
DCXR -3844.0 -362.0
DDAH1 4850.0 1577.0
DDAH2 -4544.0 1622.0
DDHD1 1781.0 3285.0
DDHD2 185.0 -2326.0
DDO -3779.0 -4353.0
DECR1 -2617.0 -4783.0
DECR2 -2311.0 2080.0
DEGS1 -2228.0 3767.0
DERA 3823.0 1200.0
DGAT1 -2804.0 -1001.0
DGAT2 387.0 -4842.0
DGUOK 2349.0 -2494.0
DHCR24 3807.0 4002.0
DHCR7 -5099.0 297.0
DHFR -3638.0 1542.5
DHODH 1292.0 -4001.0
DHRS7B -5012.0 -4352.0
DHTKD1 -419.0 -4108.0
DIO2 -666.0 2437.0
DLAT -1960.0 -3824.0
DLD 1187.0 -4737.0
DLST -323.0 -3527.0
DNM2 -1149.0 2166.0
DNPH1 -2705.0 -196.0
DPYD 1236.0 -4494.0
DSE 3382.0 2121.0
DSEL 4232.0 932.0
DTYMK -1277.0 1222.0
DUT -592.0 540.0
EBP 1444.0 1202.0
ECHS1 -3895.0 -4777.0
ECI1 -3975.0 -3414.0
ECI2 -4454.0 -4393.0
ECSIT -2655.0 -2846.0
EEF1E1 2843.0 2946.0
EEFSEC -4387.0 1275.0
EHHADH -1005.0 -3488.0
ELOVL1 -3641.0 4154.0
ELOVL5 4908.0 233.0
ELOVL6 1603.0 3638.0
ENO1 -4083.0 2473.0
ENO2 -2024.0 901.0
ENO3 -4671.0 -2856.0
ENOPH1 1391.0 1116.0
ENPP1 4114.0 4133.0
ENPP2 3080.0 -3307.0
ENPP3 -537.0 -3157.0
ENTPD5 -4035.0 -3417.0
ENTPD6 -4382.0 95.0
ENTPD7 -2365.0 4563.0
EP300 3403.0 -1622.0
EPHX1 -5101.0 2870.0
EPHX2 -2227.0 -5070.0
EPM2A -579.0 -4793.0
ERCC2 824.0 2393.0
ESD 953.0 2885.0
ESRRA -4570.0 -4245.0
ESYT1 -5390.0 3932.0
ESYT2 -3789.0 2042.0
ETFA 3160.0 -2761.0
ETFB -3614.0 -2740.0
ETFDH 1884.0 -4586.0
ETHE1 -1851.0 1197.0
ETNK1 3905.0 -2657.0
EXT1 3887.0 5027.0
EXT2 2074.0 919.0
FABP3 -5075.0 4735.0
FABP5 -338.0 -519.0
FADS1 -4196.0 3747.0
FADS2 -4594.0 442.0
FAH -3942.0 418.0
FAHD1 -1771.0 -4302.0
FAM120B -1675.0 -3875.0
FAR1 3520.0 4559.0
FASN -4976.0 3183.0
FAU 2272.0 4115.0
FBP2 -3323.0 -3226.0
FDFT1 -4290.0 -4931.0
FDPS -3811.0 706.0
FDX1 2337.0 4039.0
FDXR -4136.0 -3282.0
FECH -3768.0 -4141.0
FH 287.0 -2895.0
FHL2 -4462.0 4813.0
FIG4 -2187.0 25.0
FITM1 -5314.0 -3519.0
FITM2 -1820.0 -4133.0
FLAD1 3295.0 -5064.0
FLVCR1 1431.0 -4678.0
FMOD -329.0 -1294.0
FPGS -5408.0 -385.0
FUT10 2544.0 -2555.0
FUT11 -3756.0 105.0
FXN -2179.0 949.0
G0S2 -5182.0 -3294.0
G6PC3 -3066.0 -1492.0
G6PD 579.0 4742.0
GAA -5001.0 -3369.0
GADL1 -5127.0 -4155.0
GALC 1050.0 -2102.0
GALE -4804.0 2903.0
GALK1 -3470.0 2667.0
GALT -2687.0 -4117.0
GAMT -5400.0 -5019.0
GART 3329.0 -2304.0
GATM -2803.0 933.0
GBA -1680.0 1394.0
GBA2 -5138.0 -4972.0
GBE1 532.0 -3437.0
GCAT -3849.0 -771.0
GCDH -2239.0 -4267.0
GCH1 358.0 5157.0
GCLC 2502.0 4184.0
GCLM -818.0 -474.0
GCSH -140.0 -1034.0
GDE1 -1579.0 -2310.0
GDPD1 339.0 3575.0
GDPD3 -2758.0 1346.0
GDPD5 -5469.0 -1569.0
GGCT -1031.0 49.0
GGPS1 2567.0 -1720.0
GGT5 -954.0 -1159.0
GGT7 -2763.0 2987.0
GK 1198.0 4846.0
GLA 3418.0 -1853.0
GLB1 -2244.0 924.0
GLB1L -1827.0 -416.0
GLCE 3967.0 3994.0
GLO1 -678.0 -3885.0
GLRX 1619.0 -219.0
GLRX5 -1282.0 -2804.0
GLS 4937.0 -244.0
GLTP 486.0 2264.0
GLUD1 -360.0 -542.0
GLUL 2197.0 4878.0
GLYCTK 1312.0 -3288.0
GM2A -1169.0 2670.0
GMPR -5365.0 -4999.0
GMPR2 -1133.0 -1585.0
GMPS 3153.0 3094.0
GNA11 -1689.0 677.0
GNAI1 183.0 -419.0
GNAI2 800.0 3632.0
GNAQ 4906.0 2996.0
GNAS -3163.0 -641.0
GNB1 177.0 4937.0
GNB2 -3870.0 3905.0
GNB3 -3272.0 -1723.0
GNB4 -3491.0 -3375.0
GNB5 879.0 160.0
GNG11 4695.0 -2336.0
GNG12 612.0 -821.0
GNG2 802.0 -279.0
GNG5 415.0 -1583.0
GNG7 -2742.0 -5085.0
GNPAT -1893.0 -4700.0
GNPDA1 -244.0 58.0
GNPDA2 685.0 274.0
GNS 101.0 -979.0
GOT1 -3758.0 -1252.0
GOT2 -3704.0 -3090.0
GPAM 1132.0 -5246.0
GPC1 -5269.0 -2966.0
GPC4 -5170.0 -3500.0
GPC6 -2385.0 158.0
GPCPD1 -3490.0 -5298.0
GPD1 -5525.0 -1298.0
GPD1L -4058.0 -4298.0
GPD2 1922.0 -5242.0
GPHN -1543.0 -2845.0
GPI -5210.0 -4132.0
GPS2 2002.0 3298.0
GPT -5145.0 -5355.0
GPT2 2762.0 -5340.0
GPX1 -4411.0 3026.0
GPX4 -3706.0 -4546.0
GRHPR -4730.0 -4033.0
GSR -2148.0 1119.0
GSS -4919.0 4656.0
GSTK1 -4345.0 -4008.0
GSTM2 -4720.0 -1608.0
GSTM3 -2929.0 -4942.0
GSTM4 -5020.0 -2936.0
GSTO1 -2055.0 -2038.0
GSTT2B -3100.0 -4690.0
GSTZ1 -2068.0 -4631.0
GUK1 -1482.0 -684.0
GUSB 1923.0 4153.0
GYG1 -3875.0 4435.0
GYS1 -5384.0 -4666.0
HACL1 4520.0 -3865.0
HADH -2786.0 -5187.0
HADHA -3202.0 -2497.0
HADHB -2035.0 -3610.0
HAGH -4509.0 1245.0
HAS3 -238.0 -3298.0
HDAC3 -178.0 -4320.0
HELZ2 -2454.0 -322.0
HEXA -221.0 1746.0
HEXB 753.0 2379.0
HIBADH -4032.0 -2559.0
HIBCH 488.0 -5077.0
HILPDA 972.0 424.0
HK1 -4205.0 2075.0
HK2 4651.0 -3891.0
HLCS -758.0 -3900.0
HMBS -3958.0 -1600.0
HMGCL -4130.0 -1983.0
HMGCR 971.0 4631.0
HMGCS1 -971.0 -1296.0
HMOX1 -2843.0 5071.0
HMOX2 -687.0 552.0
HNMT -4076.0 -4979.0
HPGD 1681.0 -1199.0
HPRT1 1069.0 4675.0
HS2ST1 1682.0 2500.0
HS3ST5 -1643.0 -1208.0
HS6ST1 -2524.0 5138.0
HS6ST2 -4550.0 278.0
HSCB -134.0 -1661.0
HSD11B1 -1964.0 -3037.0
HSD17B10 -1193.0 -485.0
HSD17B11 1302.0 -627.0
HSD17B12 2118.0 5060.0
HSD17B4 689.0 -3036.0
HSD17B7 1183.0 2788.0
HSD3B7 -4371.0 1052.0
HSP90AA1 3656.0 5261.0
HSP90AB1 -639.0 4629.0
HSPG2 -5351.0 -404.0
HYAL1 -3845.0 1605.0
HYAL2 -3575.0 3569.0
HYKK -1791.0 -2933.0
IDH1 1160.0 -5189.0
IDH2 -5216.0 -3854.0
IDH3A -2155.0 -3823.0
IDH3B -2881.0 -2173.0
IDH3G -4178.0 -3128.0
IDI1 230.0 -785.0
IDS -2473.0 -3621.0
IDUA -3866.0 -4738.0
IMPA1 3774.0 4481.0
IMPA2 -3509.0 -1065.0
IMPDH1 -827.0 2546.0
IMPDH2 822.0 1907.0
INPP1 -2482.0 -1891.0
INPP4A 793.0 -2428.0
INPP4B -4822.0 4250.0
INPP5A -4116.0 -66.0
INPP5B 2499.0 2182.0
INPP5D -2433.0 4327.0
INPP5E -1642.0 -4564.0
INPP5F 2723.0 2587.0
INPP5J -2610.0 2221.0
INPP5K -907.0 -5304.0
INPPL1 -5220.0 -4249.0
INSIG1 -3105.0 4638.0
INSIG2 767.0 -2320.0
IP6K1 -1181.0 -3474.0
IP6K2 3404.0 -661.0
IP6K3 -5500.0 -5300.0
IPMK 3766.0 -44.0
IPPK 1454.0 1331.0
IQGAP1 -415.0 3217.0
ISCA1 2917.0 -3138.0
ISCA2 -2735.0 -2014.0
ISCU -3113.0 -826.0
ISYNA1 -5409.0 1924.0
ITPA -3760.0 -1024.0
ITPK1 -2911.0 3386.0
ITPKB -4873.0 -4466.0
ITPKC -5243.0 4043.0
ITPR1 4903.0 -2230.0
ITPR2 1242.0 -3115.0
ITPR3 -3631.0 -3441.0
IVD -4805.0 -5114.0
KCNB1 -5117.0 -5063.0
KCNJ11 -5488.0 -2118.0
KDSR 3114.0 2153.0
KERA 526.0 -850.0
KHK 4875.0 -2587.0
KPNB1 3619.0 3517.0
L2HGDH -262.0 -3641.0
LBR 2244.0 -1398.0
LCLAT1 3962.0 4471.0
LDHA -3251.0 -2911.0
LDHB -1491.0 -1974.0
LDLR -3949.0 4227.0
LGMN 4834.0 4463.0
LHPP -3082.0 -4036.0
LIAS -1131.0 -4699.0
LIPE -1863.0 -3661.0
LIPT1 3416.0 4658.0
LIPT2 299.0 -2638.0
LMBRD1 310.0 -1913.0
LPCAT1 -1659.0 2005.0
LPCAT3 4224.0 -2714.0
LPCAT4 -1185.0 3800.0
LPGAT1 1940.0 2488.0
LPIN1 -2877.0 -4196.0
LPIN2 3569.0 2728.0
LPIN3 -1052.0 61.0
LRP1 -3652.0 1764.0
LRP10 -3203.0 2162.0
LRP12 4543.0 4290.0
LRPPRC 1656.0 -4390.0
LSS -5278.0 3105.0
LTA4H 1584.0 4089.0
LUM -1839.0 2479.0
LYPLA1 1177.0 -3760.0
LYRM4 2696.0 3258.0
MAN2B1 -3000.0 331.0
MAN2B2 -155.0 2085.0
MAN2C1 -4801.0 -3008.0
MANBA -1928.0 -2694.0
MAOA -96.0 3927.0
MAPKAPK2 -2489.0 -645.0
MAT2A -2353.0 -3502.0
MAT2B 3692.0 -5012.0
MBOAT1 3920.0 4843.0
MBOAT2 -83.0 2820.0
MBOAT7 502.0 4342.0
MBTPS1 -3834.0 -2996.0
MBTPS2 3778.0 -4102.0
MCAT -628.0 -2815.0
MCCC1 4013.0 -4691.0
MCCC2 2204.0 -4968.0
MCEE -816.0 -4754.0
MDH1 -1091.0 -3643.0
MDH2 -4361.0 -2855.0
ME1 1789.0 -3959.0
ME2 -1789.0 3526.0
ME3 4207.0 -3719.0
MECR -3190.0 -1721.0
MED1 4772.0 -2976.0
MED10 4087.0 2651.0
MED11 -2050.0 1872.0
MED12 -2130.0 -2791.0
MED13 4601.0 4442.0
MED13L 2680.0 3613.0
MED14 2781.0 -4663.0
MED15 1233.0 4823.0
MED16 -2476.0 -4328.0
MED17 4255.0 676.0
MED18 3737.0 1006.0
MED19 3689.0 3433.0
MED20 3604.0 -3993.0
MED21 3526.0 2647.0
MED22 -2885.0 1923.0
MED23 3909.0 2513.0
MED24 -4786.0 -4086.0
MED25 2948.0 1925.0
MED26 4038.0 2036.0
MED27 1227.0 3689.0
MED28 1120.0 -610.0
MED29 3193.0 2240.0
MED30 2307.0 -28.0
MED31 4638.0 377.0
MED4 4026.0 4309.0
MED6 4813.0 2205.0
MED7 4316.0 2498.0
MED8 4163.0 -215.0
MED9 -227.0 2109.0
MGLL -5374.0 -4338.0
MGST1 427.0 -2546.0
MGST3 -3048.0 -472.0
MID1IP1 2058.0 -1719.0
MINPP1 2622.0 2433.0
MLX -346.0 -243.0
MLXIPL -3136.0 -2923.0
MLYCD -2169.0 -5249.0
MMAA 2798.0 -4327.0
MMAB -5378.0 -5342.0
MMACHC 1931.0 -3355.0
MMADHC 3242.0 -1038.0
MMS19 -1079.0 2806.0
MOCOS 958.0 3458.0
MOCS1 -3691.0 -5021.0
MOCS2 -384.0 -4118.0
MOCS3 2496.0 1962.0
MORC2 4923.0 -3391.0
MPC1 -3681.0 -3235.0
MPC2 829.0 -1736.0
MPST -5197.0 -4384.0
MRI1 -1694.0 -1526.0
MSMO1 -3763.0 4450.0
MT-CO1 -3167.0 -4114.0
MT-CYB -1355.0 -2353.0
MT-ND1 -353.0 -2211.0
MT-ND2 -1120.0 -2087.0
MT-ND4 -2086.0 -1594.0
MT-ND5 -3244.0 -2323.0
MT-ND6 816.0 -4592.0
MTAP -2515.0 -2196.0
MTF1 4744.0 930.0
MTHFD1 -2873.0 -1459.0
MTHFD2 3294.0 5260.0
MTHFD2L 1711.0 -145.0
MTHFR -5536.0 1480.0
MTHFS -39.0 1560.0
MTM1 -1860.0 -1980.0
MTMR1 1919.0 -3565.0
MTMR10 -2009.0 3918.0
MTMR12 1044.0 2737.0
MTMR14 3326.0 133.0
MTMR2 -2470.0 162.0
MTMR3 -817.0 -1821.0
MTMR4 3209.0 1995.0
MTMR6 97.0 -3118.0
MTMR9 2885.0 -3797.0
MTR 2939.0 -4500.0
MTRR 2177.0 3264.0
MVD -4915.0 3887.0
MVK -5582.0 1212.0
N6AMT1 -2374.0 -4276.0
NADK -2052.0 4386.0
NADK2 -1735.0 -3309.0
NADSYN1 -3738.0 -4442.0
NAGLU -3708.0 -713.0
NAMPT 2093.0 556.5
NAT1 4478.0 2284.0
NCOA1 2628.0 -1167.0
NCOA2 146.0 -5050.0
NCOA3 4584.0 -321.0
NCOA6 -3402.0 -3336.0
NCOR1 2625.0 -3925.0
NCOR2 -5167.0 -1521.0
NDC1 1273.0 -2350.0
NDOR1 -87.0 -1895.0
NDST1 -3078.0 -3065.0
NDUFA1 -737.0 311.0
NDUFA10 -1955.0 -3119.0
NDUFA11 -1033.0 -1135.0
NDUFA12 -1315.0 -659.0
NDUFA13 -2253.0 -2553.0
NDUFA2 -1290.0 -1978.0
NDUFA3 -3805.0 -593.0
NDUFA4 -393.0 -682.0
NDUFA5 534.0 -1670.0
NDUFA6 -77.0 -3389.0
NDUFA7 -465.0 -1825.0
NDUFA8 -602.0 -2505.0
NDUFA9 -2868.0 -2075.0
NDUFAB1 1151.0 -3257.0
NDUFAF1 1175.0 -4265.0
NDUFAF2 3504.0 -3248.0
NDUFAF3 -3581.0 -1264.0
NDUFAF4 3740.0 -2020.0
NDUFAF5 29.0 -977.0
NDUFAF6 -2555.0 -4096.0
NDUFAF7 2971.0 -457.0
NDUFB10 -3373.0 -2096.0
NDUFB11 -2103.0 -2860.0
NDUFB2 -3732.0 -962.0
NDUFB3 852.0 -1934.0
NDUFB4 -311.0 -1522.0
NDUFB5 -2039.0 -1176.0
NDUFB6 928.0 -307.0
NDUFB7 -4222.0 -1994.0
NDUFB8 -3020.0 -2917.0
NDUFB9 -996.0 -3435.0
NDUFC1 -664.0 -2904.0
NDUFC2 34.0 -2430.0
NDUFS1 -1544.0 -4374.0
NDUFS2 -3026.0 -2814.0
NDUFS3 -3567.0 -2753.0
NDUFS4 -1690.0 -2444.0
NDUFS5 -1235.0 -1924.0
NDUFS6 -1332.0 -980.0
NDUFS7 -4871.0 -1906.0
NDUFS8 -4325.0 -1999.0
NDUFV1 -4226.0 -2736.0
NDUFV3 -2378.0 -2590.0
NEU1 1863.0 4218.0
NEU3 2532.0 -4641.0
NFS1 -223.0 -4351.0
NFYA 4965.0 4269.0
NFYB 1632.0 -3915.0
NFYC -1444.0 -1181.0
NHLRC1 -3454.0 3917.0
NME1 -2381.0 -954.0
NME4 -4099.0 700.0
NMNAT1 412.0 -4862.0
NMNAT3 -378.0 -4613.0
NMRAL1 1147.0 206.0
NMRK1 -952.0 9.0
NMRK2 -5134.0 -1369.0
NNMT -1077.0 3165.0
NNT -3325.0 -2371.0
NOSIP -2487.0 -1717.0
NPAS2 -113.0 1889.0
NQO1 2413.0 -4135.0
NQO2 -4228.0 -4786.0
NR1D1 -5185.0 -985.0
NR1H2 2288.0 3553.0
NR1H3 -3630.0 -3237.0
NRF1 3039.0 4596.0
NSDHL -744.0 -2719.0
NT5C -2948.0 1611.0
NT5C1A -4696.0 -4285.0
NT5C2 -3541.0 5043.0
NT5C3A 4203.0 2858.0
NT5E 1998.0 -3634.0
NT5M -4287.0 -3603.0
NUBP1 -98.0 4348.0
NUBP2 392.0 2239.0
NUBPL -1541.0 -3546.0
NUDT1 -381.0 -3893.0
NUDT10 4564.0 -1898.5
NUDT11 4565.0 -1898.5
NUDT12 1433.0 -3664.0
NUDT13 -3450.0 -712.0
NUDT15 2604.0 -3449.0
NUDT16 -4497.0 -2488.0
NUDT19 -2286.0 -1392.0
NUDT3 -1599.0 -4774.0
NUDT4 -2656.0 5080.0
NUDT5 3490.0 -562.0
NUDT7 -3378.0 -5002.0
NUDT9 -1871.0 -1445.0
NUP107 3232.0 2949.0
NUP133 889.0 -4048.0
NUP153 4762.0 1533.0
NUP155 4306.0 -2233.0
NUP160 3998.0 1035.0
NUP188 2117.0 3830.0
NUP205 4438.0 3588.0
NUP214 3124.0 665.0
NUP35 4571.0 649.0
NUP37 -327.0 192.0
NUP43 4562.0 2216.0
NUP54 4508.0 3831.0
NUP85 3181.0 -393.0
NUP88 1244.0 2212.0
NUP93 -1503.0 3903.0
NUP98 4235.0 5066.0
OAT 393.0 -5110.0
OAZ1 -2480.0 521.0
OAZ2 -3421.0 -3287.0
OCRL 2293.0 2180.0
ODC1 5000.0 5098.0
OGDH -5268.0 -3650.0
OGN 1004.0 -1845.0
OPLAH -2761.0 -4761.0
ORMDL1 3910.0 -2803.0
ORMDL2 3463.0 2723.0
ORMDL3 893.0 3912.0
OSBP 2398.0 -1254.0
OSBPL10 4.0 923.0
OSBPL1A -2961.0 -4807.0
OSBPL2 -4737.0 -3429.0
OSBPL3 -3505.0 4706.0
OSBPL5 -4860.0 -558.0
OSBPL6 4592.0 -5158.0
OSBPL7 -5587.0 2555.0
OSBPL8 4881.0 4405.0
OSBPL9 3722.0 -4702.0
OXCT1 -106.0 -2711.0
PAICS -743.0 -3977.0
PANK1 -5200.0 -4185.0
PANK2 2471.0 990.0
PANK3 1575.0 -805.0
PANK4 -3473.0 -4681.0
PAOX 223.0 2347.0
PAPSS1 4253.0 2351.0
PAPSS2 1717.0 384.0
PARP10 -4978.0 -2806.0
PARP14 -1721.0 -1087.0
PARP16 -79.0 -2268.0
PARP4 -4440.0 2701.0
PARP6 448.0 419.0
PARP8 4194.0 1232.0
PARP9 -3114.0 22.0
PC -5226.0 -3696.0
PCCA -2597.0 -5205.0
PCCB -165.0 -4143.0
PCK2 -2317.0 375.0
PCTP -322.0 -1700.0
PCYT1A -2527.0 -4053.0
PCYT2 -4448.0 -4045.0
PDHA1 -2405.0 -4451.0
PDHB -133.0 -3995.0
PDHX -126.0 -3872.0
PDK1 4600.0 -3234.0
PDK2 -5450.0 -3535.0
PDK3 4747.0 4864.0
PDK4 -712.0 -5238.0
PDP1 -2175.0 -4603.0
PDP2 -2619.0 -2438.0
PDPR -632.0 -4831.0
PDSS1 4374.0 -1965.0
PDSS2 998.0 -3881.0
PDXK -4690.0 -834.0
PDZD11 1678.0 490.0
PECR -1213.0 -3600.0
PEMT -3689.0 -415.0
PEX11A 934.0 -4889.0
PFAS -623.0 -4772.0
PFKFB1 -3021.0 -5126.0
PFKFB2 -4240.0 -4762.0
PFKFB3 2321.0 -5178.0
PFKFB4 -1766.0 -4129.0
PFKL -4966.0 4932.0
PFKM -4574.0 -3908.0
PFKP -2129.0 4711.0
PGAM2 -5379.0 -2929.0
PGD -199.0 4381.0
PGK1 -1414.0 -3515.0
PGLS -2896.0 1504.0
PGM1 -4270.0 -4493.0
PGM2 -561.0 3964.0
PGM2L1 4913.0 -4790.0
PGP -2575.0 -3070.0
PGS1 -795.0 2507.0
PHGDH -232.0 3172.0
PHKA1 -3965.0 -5221.0
PHKA2 -3873.0 -4213.0
PHKB -3289.0 -5059.0
PHKG1 -5495.0 -5329.0
PHKG2 -225.0 3213.0
PHOSPHO1 -1466.0 -318.0
PHYH -4170.0 -2205.0
PHYKPL -5050.0 -3953.0
PI4K2A 1510.0 5040.0
PI4K2B 1087.0 2894.0
PI4KA -2484.0 1294.0
PI4KB 1642.0 2955.0
PIAS4 342.0 2088.0
PIK3C2A 2851.0 -540.0
PIK3C2B -5561.0 -3772.0
PIK3C3 3439.0 -1648.0
PIK3CA 365.0 2811.0
PIK3CB 2760.0 4994.0
PIK3CD -4322.0 -4161.0
PIK3R1 2896.0 -3147.0
PIK3R3 3188.0 577.0
PIK3R4 3839.0 -3531.0
PIKFYVE 4791.0 1602.0
PIP4K2A 4108.0 4491.0
PIP4K2C 2827.0 2664.0
PIP5K1A 4918.0 -551.0
PIP5K1C -1917.0 390.0
PISD 15.0 -2562.0
PITPNB 3953.0 3937.0
PITPNM1 -4916.0 1317.0
PITPNM2 -5437.0 -3348.0
PKM -4231.0 -4264.0
PLA1A -1379.0 2263.0
PLA2G12A 2265.0 -2040.0
PLA2G15 -5459.0 495.0
PLA2G4A 603.0 3705.0
PLA2G6 -3913.0 -525.0
PLA2R1 66.0 -3642.0
PLB1 -3857.0 -205.0
PLBD1 1550.0 -4662.0
PLCB1 -1580.0 -1155.0
PLCB3 -3863.0 -679.0
PLCB4 -4274.0 -3778.0
PLCD1 -3494.0 -2475.0
PLCD3 -5573.0 339.0
PLCD4 -4964.0 -4749.0
PLCE1 -4858.0 -2084.0
PLCG1 -3955.0 -4939.0
PLD1 55.0 -779.0
PLD2 -60.0 -4810.0
PLD3 -5217.0 573.0
PLEKHA1 -4791.0 4758.0
PLEKHA2 -5155.0 -4165.0
PLEKHA3 3763.0 317.0
PLEKHA4 -1772.0 3385.0
PLEKHA5 3159.0 1469.0
PLEKHA6 -5554.0 -2306.0
PLEKHA8 2098.0 -856.0
PLIN2 -4079.0 4862.0
PLIN3 -5023.0 -5040.0
PMVK -2891.0 -1796.0
PNP 5019.5 4586.0
PNPLA2 -5011.0 -4886.0
PNPLA3 -2170.0 -5222.0
PNPLA6 989.0 -3042.0
PNPLA7 -4601.0 -5353.0
PNPLA8 2977.0 -3933.0
PNPO -3095.0 -984.0
PODXL2 -4588.0 -2240.0
POLD1 -3218.0 580.0
PON2 -2005.0 2827.0
POR -5507.0 5113.0
PPA1 1522.0 830.0
PPA2 -163.0 -964.0
PPARA -4997.0 -4570.0
PPARD -4213.0 -2337.0
PPARG -1621.0 -2269.0
PPARGC1A -4212.0 -5006.0
PPARGC1B -5257.0 -4147.0
PPAT 2768.0 -3683.0
PPCDC -3702.0 -4101.0
PPCS 3010.0 -528.0
PPIP5K1 -2557.0 -5004.0
PPIP5K2 3204.0 595.0
PPM1K 2278.0 -5215.0
PPM1L -5249.0 -4014.0
PPOX -3785.0 -3675.0
PPP1CA -4408.0 701.0
PPP1CB -1374.0 -4149.0
PPP1CC 4081.0 399.0
PPP1R3C -5015.0 4049.0
PPP2CA 4482.0 3008.0
PPP2CB 2458.0 4129.0
PPP2R1A -4013.0 -696.0
PPP2R1B 3028.0 4619.0
PPP2R5D -3449.0 -2058.0
PPT1 2553.0 -716.0
PPT2 -3952.0 -1952.0
PRKAA2 -3219.0 -5163.0
PRKAB2 -2332.0 -2820.0
PRKACA -4691.0 -1606.0
PRKACB -2659.0 -1546.0
PRKAG2 -3237.0 -3533.0
PRKAR1A -3106.0 3030.0
PRKAR1B -2442.0 2761.0
PRKAR2A -2664.0 -655.0
PRKAR2B 3460.0 2616.0
PRKCA -2938.0 -2924.0
PRKD1 -5136.0 2091.0
PRKD2 635.0 -1336.0
PRKD3 719.0 1974.0
PRODH -3891.0 -4695.0
PRPS1 3067.0 3023.0
PRPS2 3570.0 1819.0
PSAP -2247.0 -4040.0
PSAT1 2572.0 5123.0
PSMA1 2820.0 3328.0
PSMA3 3434.0 -4.0
PSMA4 769.0 958.0
PSMA6 2199.0 -1044.0
PSMA7 -2980.0 976.0
PSMB1 954.0 2628.0
PSMB10 -1800.0 2907.0
PSMB2 618.0 2471.0
PSMB4 -235.0 2096.0
PSMB5 -4113.0 -606.0
PSMB6 -793.0 914.0
PSMB7 -831.0 -1453.0
PSMB8 -675.0 2066.0
PSMB9 -1611.0 -2973.0
PSMC1 449.0 -336.0
PSMC2 -1311.0 3241.0
PSMC3 -2439.0 -369.0
PSMC4 2724.0 1416.0
PSMC5 1212.0 -1123.0
PSMC6 -2520.0 3423.0
PSMD1 2619.0 -1191.0
PSMD10 -1227.0 525.0
PSMD11 995.0 5183.0
PSMD12 3831.0 536.0
PSMD13 821.0 1665.0
PSMD14 -635.0 3816.0
PSMD2 -713.0 -555.0
PSMD3 -3343.0 2226.0
PSMD4 -214.0 2558.0
PSMD5 1807.0 3558.0
PSMD6 3537.0 -2207.0
PSMD7 -2329.0 1233.0
PSMD8 -3171.0 4626.0
PSMD9 4204.0 -970.0
PSME1 -2771.0 3350.0
PSME2 -4085.0 3584.0
PSME3 3333.0 3379.0
PSME4 1960.0 -4574.0
PSMF1 683.0 -1480.0
PSPH -872.0 -791.0
PSTK 2140.0 -3556.0
PTDSS1 -325.0 1904.0
PTDSS2 -4414.0 -3218.0
PTEN 2797.0 2721.0
PTGES -495.0 -1083.0
PTGES2 -2699.0 -3434.0
PTGES3 1328.0 3635.0
PTGIS -1921.0 936.0
PTGR1 3646.0 2742.0
PTGR2 -1055.0 -4877.0
PTGS1 -854.0 417.0
PTPN13 4200.0 -863.0
PTS 1355.0 -3598.0
PXMP2 -1741.0 -3834.0
PYCR1 -5006.0 1562.0
PYCR2 181.0 1149.0
PYCRL -3263.0 -109.0
PYGB -4498.0 1915.0
PYGL -3546.0 4121.0
PYGM -5462.0 -4619.0
QDPR -1426.0 -3321.0
RAB14 2341.0 -844.0
RAB4A 1790.0 -2437.0
RAB5A 2109.0 4941.0
RAE1 4471.0 2389.0
RAN 2329.0 1938.0
RANBP2 4470.0 -3848.0
RAP1A -689.0 3710.0
RAPGEF3 108.0 -2918.0
RAPGEF4 4622.0 3189.0
RBKS -299.0 -1372.0
RBP1 2113.0 1028.0
RDH11 2085.0 5094.0
RETSAT 2667.0 -5363.0
RFK 4952.0 -3596.0
RGL1 -161.0 307.0
RNLS 1068.0 -3023.0
RORA -5056.0 -2699.0
RPE 3419.0 -2197.0
RPIA 1665.0 -1013.0
RPL10 -3902.0 3841.0
RPL11 -2249.0 2690.0
RPL14 433.0 1505.0
RPL18 -1782.0 3926.0
RPL18A -2969.0 1546.0
RPL19 -502.0 2402.0
RPL22 1231.0 -695.0
RPL22L1 3380.0 4103.0
RPL23 -115.0 2472.0
RPL26 1047.0 3247.0
RPL28 -391.0 2871.0
RPL3 -786.0 4892.0
RPL30 286.0 2070.0
RPL31 -595.0 4273.0
RPL32 -367.0 2766.0
RPL34 1447.0 1856.0
RPL35A 812.0 1955.0
RPL36A 1261.0 2266.0
RPL37 -715.0 2388.0
RPL37A -1043.0 2280.0
RPL38 231.0 3306.0
RPL3L -5212.0 -3395.0
RPL4 -522.0 1026.0
RPL5 1206.0 4486.0
RPL7 1440.0 1916.0
RPL8 -2775.0 2474.0
RPLP2 -2469.0 2383.0
RPS11 -1582.0 3395.0
RPS12 -318.0 3958.0
RPS13 1131.0 3118.0
RPS14 -1412.0 1322.0
RPS15 -1799.0 1989.0
RPS15A -704.0 2410.0
RPS16 -1828.0 3864.0
RPS18 -974.0 2916.0
RPS19 -2045.0 2954.0
RPS20 -1844.0 4785.0
RPS21 -1536.0 707.0
RPS23 -68.0 1922.0
RPS24 256.0 1742.0
RPS26 -282.0 2982.0
RPS27A 783.0 1840.0
RPS27L -616.0 298.0
RPS29 -1140.0 2499.0
RPS3 -544.0 3102.0
RPS4X 83.0 1892.0
RPS5 -1577.0 2419.0
RPS6 -245.0 3549.0
RPS8 -1593.0 2271.0
RPS9 -1107.0 1580.0
RRM1 1649.0 -2255.0
RRM2B -887.0 -4977.0
RUFY1 -2429.0 -3415.0
RXRA -5519.0 -4191.0
RXRB -1250.0 -3372.0
SACM1L 4950.0 -3022.0
SAMD8 4892.0 4198.0
SAMHD1 48.0 3058.0
SAR1B 2914.0 -4240.0
SARDH -5204.0 3770.0
SAT1 4359.0 3647.0
SBF1 -3064.0 1820.0
SBF2 -32.0 -2469.0
SC5D 440.0 -3120.0
SCAP -3464.0 -3305.0
SCD -5600.0 3966.0
SCLY 2743.0 3396.0
SCO1 3577.0 1708.0
SCO2 -1941.0 -772.0
SCP2 -862.0 -4937.0
SDC1 -2046.0 212.0
SDC2 1756.0 4483.0
SDC3 -4619.0 2809.0
SDC4 -2393.0 5153.0
SDHA -4773.0 -4591.0
SDHB 431.0 -3707.0
SDHC -3712.0 -3001.0
SEC13 730.0 1702.0
SEC23A 3177.0 -4175.0
SEC24A 4282.0 -1165.0
SEC24B 3112.0 1867.0
SEC24C 2739.0 1614.0
SEC24D 265.0 4150.0
SECISBP2 1385.0 1671.0
SEH1L 1085.0 4263.0
SEPHS2 4570.0 5191.0
SEPSECS 733.0 2048.0
SERINC1 2847.0 -3061.0
SERINC2 -5279.0 -691.0
SERINC3 1718.0 738.0
SERINC5 4920.0 -1327.0
SGMS1 3348.0 2210.0
SGMS2 -580.0 4620.0
SGPL1 836.0 3820.0
SGPP1 2488.0 4374.0
SGSH 710.0 -512.0
SHMT1 -4478.0 -4020.0
SHMT2 -3440.0 1392.0
SIN3A 3397.0 267.0
SIN3B 1030.0 2716.0
SLC16A1 -987.0 5075.0
SLC16A3 -4751.0 -4158.0
SLC19A1 -3727.0 -1017.0
SLC19A2 2276.0 -1844.0
SLC22A5 -4653.0 -2940.0
SLC23A2 1949.0 514.0
SLC25A1 -2688.0 3732.0
SLC25A11 -4108.0 -3843.0
SLC25A12 -5347.0 -4548.0
SLC25A13 4283.0 3607.0
SLC25A14 3834.0 1871.0
SLC25A16 1926.0 -4366.0
SLC25A17 4134.0 3995.0
SLC25A19 -626.0 -3859.0
SLC25A20 -3511.0 -1437.0
SLC25A27 -2478.0 -4864.0
SLC25A28 1627.0 2794.0
SLC25A32 4603.0 -2689.0
SLC25A37 -4181.0 -3200.0
SLC25A44 4847.0 2439.0
SLC26A2 1389.0 2030.0
SLC27A1 -5082.0 -4960.0
SLC27A3 -132.0 -262.0
SLC2A1 -2288.0 4737.0
SLC2A3 5004.0 2971.5
SLC35B2 -4343.0 1199.0
SLC35B3 1732.0 462.0
SLC35D1 1549.0 173.0
SLC35D2 -2864.0 1797.0
SLC36A4 3115.0 2202.0
SLC37A1 -2590.0 -201.0
SLC37A4 -4766.0 -5052.0
SLC3A2 -656.0 3875.0
SLC44A1 -686.0 -78.0
SLC44A2 -5438.0 -4740.0
SLC46A1 -3599.0 -946.0
SLC52A2 1190.0 4786.0
SLC5A6 -433.0 -43.0
SLC6A8 -5538.0 4390.0
SLC7A5 -2463.0 4541.0
SLC9A1 -1056.0 -261.0
SMARCD3 -5399.0 -4597.0
SMOX -1111.0 -5194.0
SMPD1 56.0 -2883.0
SMPD2 -1826.0 -3571.0
SMPD4 4257.0 -1523.0
SMS -3038.0 620.0
SORD -2721.0 4646.0
SP1 1787.0 -1016.0
SPHK1 443.0 3714.0
SPHK2 -3750.0 3429.0
SPNS2 117.0 -2807.0
SPR -5076.0 1834.0
SPTLC1 4025.0 1223.0
SPTLC2 -355.0 3970.0
SPTSSA 61.0 -190.0
SQLE -4496.0 4580.0
SQRDL -4048.0 -4887.0
SRD5A3 3461.0 2937.0
SREBF1 -5230.0 594.0
SREBF2 -4703.0 4517.0
SRM 878.0 4476.0
SRR -3331.0 -3107.0
ST3GAL1 -4505.0 4024.0
ST3GAL2 -2316.0 -4984.0
ST3GAL3 -4844.0 -2274.0
ST3GAL4 -2946.0 3771.0
ST3GAL6 -2222.0 -2692.0
ST6GALNAC6 -5270.0 -2466.0
STAB2 -3254.0 -3801.0
STARD10 -1854.0 3501.0
STARD3 -137.0 -1756.0
STARD3NL -868.0 4525.0
STARD4 -288.0 3564.0
STARD5 -3200.0 953.0
STARD7 -4664.0 -4944.0
STK11 -4884.0 -2152.0
STX1A -411.0 1613.0
STXBP1 -2263.0 2250.0
SUCLA2 1517.0 -4376.0
SUCLG1 -31.0 -2136.0
SUCLG2 -1167.0 -4291.0
SULT1A1 -2443.0 -2724.0
SUMF1 -289.0 -1573.0
SUMF2 -1393.0 3765.0
SUOX -2894.0 -4930.0
SURF1 -1748.0 -4099.0
SYNJ1 4959.0 3293.0
SYNJ2 -3941.0 -5345.0
TACO1 651.0 -4262.0
TALDO1 -2080.0 -766.0
TAZ -3604.0 -5130.0
TBL1XR1 1876.0 -2165.0
TCN2 -1729.0 -2170.0
TECR -4006.0 -2727.0
TGS1 4576.0 2059.0
THEM4 -3616.0 -500.0
THRAP3 2457.0 661.0
THRSP -4308.0 -4642.0
THTPA -2779.0 -4491.0
TIAM2 -3379.0 5163.0
TIMMDC1 213.0 -1107.0
TK1 -3225.0 906.0
TK2 -3502.0 2660.0
TKT -3051.0 3694.0
TM7SF2 -3964.0 -2773.0
TMEM126B 1024.0 1869.0
TMEM55B 3859.0 2821.0
TMEM86B 2486.0 2730.0
TMLHE -1794.0 -1840.0
TNFAIP8 -3086.0 1796.0
TNFAIP8L1 -3667.0 -2836.0
TNFRSF21 -2507.0 -4518.0
TPH1 -823.0 -4373.0
TPI1 -3377.0 -4476.0
TPK1 3959.0 -1432.0
TPMT 2687.0 -1981.0
TPR 2984.0 -1026.0
TPST1 2003.0 1582.0
TPST2 -2855.0 -1220.0
TRAP1 -5265.0 -2063.0
TRIB3 -1004.0 3791.0
TSPO -5144.0 4102.0
TST -4513.0 -5243.0
TXN 1855.0 4791.0
TXN2 -2838.0 641.0
TXNRD1 -2444.0 2445.0
TYMS -2042.0 2614.0
UBC 2672.0 4480.0
UBE2I 1246.0 1214.0
UBIAD1 923.0 -1132.0
UCK1 -2612.0 469.0
UCK2 -3433.0 5236.0
UCKL1 -3830.0 -3599.0
UCP2 -4949.0 5039.0
UCP3 -684.0 -5360.0
UGCG 2596.0 4332.0
UGDH 2788.0 4270.0
UGP2 1387.0 1523.0
UMPS 1369.0 1160.0
UQCR10 -3139.0 -259.0
UQCRB 403.0 -3715.0
UQCRC1 -3333.0 -3667.0
UQCRC2 551.0 -3907.0
UQCRFS1 -151.0 -3062.0
UQCRH -1532.0 -1753.0
UQCRQ -1767.0 -1856.0
UROD 795.0 -3244.0
UROS -1848.0 -4416.0
UST 999.0 1419.0
VAC14 -3820.0 1081.0
VAMP2 -3293.0 1812.0
VAPA 2838.0 2906.0
VAPB -1377.0 -3712.0
VCAN 1679.0 4433.0
VDAC1 -2909.0 -4606.0
VKORC1 -1589.0 670.0
VKORC1L1 -1211.0 -928.0
WASL 2683.0 3268.0
XYLT1 2612.0 2950.0
XYLT2 -1138.0 1328.0
ZDHHC21 331.0 309.0



rRNA modification in the nucleus and cytosol

rRNA modification in the nucleus and cytosol
metric value
setSize 52
pMANOVA 3.48e-15
p.adjustMANOVA 3.3e-13
s.dist 0.698
s.human 0.6
s.mouse 0.356
p.human 7.07e-14
p.mouse 8.87e-06




Top 20 genes
Gene human mouse
UTP14A 4777 5037.5
NOP58 4891 4343.0
DCAF13 4800 4163.0
GAR1 4132 4763.0
HEATR1 4911 3855.0
WDR3 4838 3546.0
WDR43 4883 3479.0
NOP2 3472 4824.0
WDR36 4542 3505.0
UTP3 4917 2928.0
UTP18 3851 3736.0
IMP4 2805 4315.0
NOP56 3099 3859.0
UTP15 4137 2775.0
MPHOSPH10 3928 2826.0
NOL6 3819 2763.0
FBL 4233 2213.0
WDR75 3743 2374.0
WDR46 3335 2646.0
DDX49 2178 4026.0

Click HERE to show all gene set members

All member genes
human mouse
BMS1 3511 -4218.0
DCAF13 4800 4163.0
DDX47 3735 1436.0
DDX49 2178 4026.0
DHX37 2105 2976.0
DIEXF 4877 1147.0
DIMT1 2537 1451.0
DKC1 3629 -171.0
FBL 4233 2213.0
FCF1 3303 2053.0
GAR1 4132 4763.0
HEATR1 4911 3855.0
IMP3 4536 -961.0
IMP4 2805 4315.0
KRR1 3921 1112.0
MPHOSPH10 3928 2826.0
NAT10 3642 -1157.0
NHP2 694 2676.0
NOC4L 1763 2013.0
NOL11 4916 -392.0
NOL6 3819 2763.0
NOP10 1336 911.0
NOP14 1590 4393.0
NOP2 3472 4824.0
NOP56 3099 3859.0
NOP58 4891 4343.0
PDCD11 -1465 815.0
PNO1 4623 332.0
PWP2 2462 745.0
RCL1 3257 -48.0
RPS14 -1412 1322.0
RPS6 -245 3549.0
RPS9 -1107 1580.0
RRP36 1532 1854.0
RRP7A 2138 3626.0
RRP9 771 2325.0
TBL3 -1551 1063.0
THUMPD1 4666 -2564.0
TSR3 -3611 -3279.0
UTP14A 4777 5037.5
UTP14C 1565 5037.5
UTP15 4137 2775.0
UTP18 3851 3736.0
UTP20 4174 240.0
UTP3 4917 2928.0
UTP6 4779 -4513.0
WBSCR22 1741 -1538.0
WDR3 4838 3546.0
WDR36 4542 3505.0
WDR43 4883 3479.0
WDR46 3335 2646.0
WDR75 3743 2374.0



Cell Cycle

Cell Cycle
metric value
setSize 484
pMANOVA 4.05e-15
p.adjustMANOVA 3.56e-13
s.dist 0.234
s.human 0.193
s.mouse 0.134
p.human 7.18e-13
p.mouse 6.28e-07




Top 20 genes
Gene human mouse
PPME1 4727 5198
NUP98 4235 5066
CCNE1 4388 4753
TOP2A 4691 4445
BRCA2 4886 4229
CEP152 4492 4513
RAD21 4417 4508
FBXW11 4385 4535
GAR1 4132 4763
CHTF8 3753 5202
MYC 3994 4886
POLR2A 3861 5046
PPP2R5A 4590 4219
HSP90AA1 3656 5261
UBE2S 4441 4268
DAXX 4449 4197
DBF4 4260 4331
SKP2 4205 4385
HSPA2 4948 3536
NUP54 4508 3831

Click HERE to show all gene set members

All member genes
human mouse
AAAS -3476 1550.0
ABL1 -4533 -3545.0
ACD -1324 68.0
ACTR1A -4126 1651.0
AHCTF1 4662 -1792.0
AJUBA -4112 -892.0
AKAP9 -573 -5181.0
AKT1 -4954 342.0
AKT2 -4057 -4450.0
AKT3 1343 -320.0
ALMS1 4347 1162.0
ANAPC1 572 -4087.0
ANAPC10 1974 2134.0
ANAPC11 -3265 -1751.0
ANAPC15 -3393 1787.0
ANAPC16 -3612 -1148.0
ANAPC2 -2185 -3532.0
ANAPC4 -720 -4834.0
ANAPC5 1284 -2104.0
ANAPC7 1595 2349.0
ANKLE2 1499 855.0
ANKRD28 1927 -5240.0
ARPP19 2927 4020.0
ATM 1449 -5067.0
ATR 1983 -63.0
ATRX 3995 -3923.0
AURKA 3811 325.0
B9D2 1676 -553.0
BABAM1 -1363 -802.0
BANF1 -2281 674.0
BLM 1103 4695.0
BLZF1 4266 115.0
BORA 4768 3401.0
BRCA2 4886 4229.0
BRCC3 -375 -3072.0
BRE 696 -809.0
BTRC -1187 -2758.0
BUB3 4201 1662.0
CABLES1 -4484 459.0
CC2D1B 1025 39.0
CCNA2 3061 4292.0
CCND1 757 529.0
CCND2 225 405.0
CCND3 786 1371.0
CCNE1 4388 4753.0
CCNE2 4667 147.0
CCNH 3825 -1657.0
CCP110 4605 -630.0
CDC14A 957 -3217.0
CDC16 86 -1984.0
CDC23 3850 -1171.0
CDC25A 4090 2308.0
CDC25B 4652 2780.0
CDC26 2750 2457.0
CDC27 665 1230.0
CDC7 2421 2065.0
CDK1 1580 3263.0
CDK11A 167 -180.5
CDK11B 1690 -180.5
CDK2 849 2686.0
CDK4 703 3417.0
CDK5RAP2 -3037 -1178.0
CDK6 1090 3036.0
CDK7 1571 -2032.0
CDKN1A -4927 5092.0
CDKN1B -3284 -2450.0
CDKN1C -5394 -4228.0
CDKN2B -2827 2812.0
CDKN2C 3612 3091.0
CDKN2D 142 -1212.0
CENPC 3555 -2660.0
CENPJ 1720 -467.0
CENPL 3768 2470.0
CENPO 1005 440.0
CENPQ 1344 5001.0
CENPT -2196 3930.0
CEP135 1891 -1400.0
CEP152 4492 4513.0
CEP164 3699 1799.0
CEP192 2073 -303.0
CEP250 3192 -3961.0
CEP290 3352 -4522.0
CEP41 4357 1396.0
CEP57 611 -1027.0
CEP63 -2491 -663.0
CEP70 -3094 -96.0
CEP76 3163 2269.0
CEP78 3895 -777.0
CETN2 -587 -2273.0
CHEK2 1311 1076.0
CHMP2A 1155 2310.0
CHMP2B 967 -4167.0
CHMP3 -3919 1578.0
CHMP4B -1125 329.0
CHMP6 -4368 279.0
CHMP7 1743 -3701.0
CHTF8 3753 5202.0
CKAP5 -3973 -1370.0
CKS1B 1446 4555.0
CLASP1 -3713 1181.0
CLASP2 2507 -309.0
CLIP1 418 -4689.0
CNEP1R1 1729 -2101.0
CNTRL 4333 -5162.0
CSNK1D -3539 3832.0
CSNK1E -5045 816.0
CSNK2A1 1796 -1733.0
CSNK2A2 2123 1393.0
CSNK2B 1917 -296.0
CTC1 1689 -3371.0
CTDNEP1 -2509 -1879.0
CUL1 -3121 -1536.0
DAXX 4449 4197.0
DBF4 4260 4331.0
DCTN1 -347 -2402.0
DCTN2 -3157 -448.0
DCTN3 -943 2888.0
DHFR -3638 1542.5
DIDO1 1299 -2726.0
DKC1 3629 -171.0
DNA2 37 2385.0
DSN1 2075 534.0
DYNC1H1 -1442 -2348.0
DYNC1I2 2591 -2971.0
DYNC1LI1 2883 1316.0
DYNC1LI2 1750 -1620.0
DYNLL1 -1331 4245.0
DYRK1A -2401 2200.0
E2F1 -529 4663.0
E2F3 -4683 -1694.0
E2F4 -439 5017.0
E2F5 -249 2797.0
E2F6 650 -3768.0
EMD -651 3538.0
EML4 4736 3589.0
ENSA -114 -1834.0
EP300 3403 -1622.0
ESCO1 680 -2410.0
ESPL1 408 4211.0
FAM175A -3897 129.0
FBXL18 1610 -2831.0
FBXW11 4385 4535.0
FEN1 4094 3551.0
FKBPL 4474 3673.0
FZR1 -1244 3620.0
GAR1 4132 4763.0
GINS1 441 1703.0
GINS3 -1006 2295.0
GINS4 -1475 -1046.0
GMNN 4714 -3905.0
GOLGA2 919 -3262.0
GORASP1 -4615 -2387.0
GORASP2 2697 3743.0
GSK3B 897 3200.0
H2AFX 2356 5062.0
HAUS1 1263 722.0
HAUS2 2905 109.0
HAUS3 3748 4141.0
HAUS4 -2191 -1774.0
HAUS6 3590 -1282.0
HAUS8 758 3915.0
HDAC8 209 -3381.0
HSP90AA1 3656 5261.0
HSP90AB1 -639 4629.0
HSPA2 4948 3536.0
HUS1 2435 -4471.0
INCENP 3676 3359.0
IST1 3827 4131.0
ITGB3BP 1048 -2448.0
JAK2 -2569 -5057.0
KAT5 447 3955.0
KIF18A 3832 4144.0
KIF23 1216 4134.0
KIF2A -4390 4818.0
KPNB1 3619 3517.0
LBR 2244 -1398.0
LCMT1 729 -996.0
LEMD2 -1073 679.0
LEMD3 3330 1458.0
LIG1 -3127 3257.0
LIN37 -1988 4591.0
LIN52 915 -4751.0
LIN54 4080 -2234.0
LIN9 1166 -4383.0
LMNA -4692 5155.0
LMNB1 3392 2947.0
LPIN1 -2877 -4196.0
LPIN2 3569 2728.0
LPIN3 -1052 61.0
LYN 785 3984.0
MAD1L1 -3382 2990.0
MAD2L1 1101 3554.0
MAPK1 1988 -648.0
MAPK3 -1024 3725.0
MAPRE1 3454 4528.0
MAU2 -3188 -2899.0
MAX -2352 1069.0
MCM2 -3977 2851.0
MCM3 600 4761.0
MCM4 -610 4841.0
MCM5 -1490 4861.0
MCM6 3462 4822.0
MCM7 2515 2881.0
MCM8 -3355 -3274.0
MCPH1 2176 -1854.0
MDC1 841 2997.0
MDM2 3253 3321.0
MDM4 2051 -4809.0
MIS12 2400 4069.0
MIS18A 4613 1015.0
MLH1 -1210 -4562.0
MLH3 -407 -4725.0
MNAT1 830 -2433.0
MYC 3994 4886.0
MZT1 3517 -4547.0
MZT2A -3883 -2023.5
MZT2B -3442 -2023.5
NBN 1286 -1205.0
NCAPD2 4017 -3000.0
NCAPD3 3002 -4897.0
NCAPG2 -13 1154.0
NCAPH 1129 3314.0
NCAPH2 -1845 -2829.0
NDC1 1273 -2350.0
NDE1 4322 -2784.0
NDEL1 4631 1071.0
NEDD1 1034 -933.0
NEK6 -5042 2173.0
NEK7 535 -2342.0
NEK9 -2856 -2338.0
NHP2 694 2676.0
NIPBL 4675 -4955.0
NME7 2020 -685.0
NOP10 1336 911.0
NUDC 3212 2586.0
NUMA1 -4395 -1953.0
NUP107 3232 2949.0
NUP133 889 -4048.0
NUP153 4762 1533.0
NUP155 4306 -2233.0
NUP160 3998 1035.0
NUP188 2117 3830.0
NUP205 4438 3588.0
NUP214 3124 665.0
NUP35 4571 649.0
NUP37 -327 192.0
NUP43 4562 2216.0
NUP54 4508 3831.0
NUP85 3181 -393.0
NUP88 1244 2212.0
NUP93 -1503 3903.0
NUP98 4235 5066.0
ODF2 1954 -1185.0
OFD1 811 -3024.0
OPTN 1980 -1925.0
ORC2 1022 4505.0
ORC3 -1627 -3964.0
ORC4 3929 1594.0
ORC5 4429 -566.0
ORC6 2184 -425.0
PAFAH1B1 -2026 -2663.0
PCBP4 -5523 -1872.0
PCM1 1788 -4915.0
PCNA 1329 5082.0
PCNT -1269 -5149.0
PDS5A 1248 -2950.0
PDS5B -3191 -5111.0
PHF20 819 -2632.0
PHF8 3393 2137.0
PHLDA1 -3126 5180.0
PIAS4 342 2088.0
PLK4 3581 2306.0
POLA1 1944 1826.0
POLA2 -173 -1993.0
POLD1 -3218 580.0
POLD2 -4806 1491.0
POLD3 3486 1097.0
POLD4 -2084 3728.0
POLE -3659 436.0
POLE2 1264 3777.0
POLE3 4335 -269.0
POLE4 409 3529.0
POLR2A 3861 5046.0
POLR2B 4509 -4119.0
POLR2C 4529 -904.0
POLR2D 1669 2692.0
POLR2E -667 1599.0
POLR2G 89 5112.0
POLR2H -3927 3497.0
POLR2I -154 81.0
POLR2K 2480 -1584.0
POLR2L -4314 4110.0
POT1 3936 -4021.0
PPME1 4727 5198.0
PPP1CB -1374 -4149.0
PPP1CC 4081 399.0
PPP1R12A 4131 2449.0
PPP1R12B -5005 -1873.0
PPP2CA 4482 3008.0
PPP2CB 2458 4129.0
PPP2R1A -4013 -696.0
PPP2R1B 3028 4619.0
PPP2R2A 2264 3799.0
PPP2R2D -2153 2506.0
PPP2R5A 4590 4219.0
PPP2R5B -1524 121.0
PPP2R5C -2508 -3684.0
PPP2R5D -3449 -2058.0
PPP2R5E 4644 1539.0
PPP6C 3109 -3191.0
PPP6R3 3079 -686.0
PRIM1 311 3722.0
PRIM2 3544 4441.0
PRKACA -4691 -1606.0
PRKAR2B 3460 2616.0
PRKCA -2938 -2924.0
PSMA1 2820 3328.0
PSMA3 3434 -4.0
PSMA4 769 958.0
PSMA6 2199 -1044.0
PSMA7 -2980 976.0
PSMB1 954 2628.0
PSMB10 -1800 2907.0
PSMB2 618 2471.0
PSMB4 -235 2096.0
PSMB5 -4113 -606.0
PSMB6 -793 914.0
PSMB7 -831 -1453.0
PSMB8 -675 2066.0
PSMB9 -1611 -2973.0
PSMC1 449 -336.0
PSMC2 -1311 3241.0
PSMC3 -2439 -369.0
PSMC3IP 2987 3746.0
PSMC4 2724 1416.0
PSMC5 1212 -1123.0
PSMC6 -2520 3423.0
PSMD1 2619 -1191.0
PSMD10 -1227 525.0
PSMD11 995 5183.0
PSMD12 3831 536.0
PSMD13 821 1665.0
PSMD14 -635 3816.0
PSMD2 -713 -555.0
PSMD3 -3343 2226.0
PSMD4 -214 2558.0
PSMD5 1807 3558.0
PSMD6 3537 -2207.0
PSMD7 -2329 1233.0
PSMD8 -3171 4626.0
PSMD9 4204 -970.0
PSME1 -2771 3350.0
PSME2 -4085 3584.0
PSME3 3333 3379.0
PSME4 1960 -4574.0
PSMF1 683 -1480.0
PTTG1 4843 -2819.0
RAB1A 3634 4583.0
RAB1B -2997 67.0
RAB2A 1999 -249.0
RAB8A 3378 2789.0
RAD1 3205 3561.0
RAD17 2273 808.0
RAD21 4417 4508.0
RAD50 306 -3473.0
RAD51 63 -2396.0
RAD9A -3149 -154.0
RAE1 4471 2389.0
RAN 2329 1938.0
RANBP2 4470 -3848.0
RANGAP1 483 4340.0
RB1 -2449 1464.0
RBBP4 1072 2469.0
RBBP7 -924 -2291.0
RBBP8 3047 3316.0
RBL1 -1617 778.0
RBL2 -242 -5105.0
RBX1 -733 -968.0
RCC1 997 3619.0
RCC2 4178 3436.0
RFC1 4641 1093.0
RFC2 622 -1170.0
RFC3 2151 4113.0
RFC4 3542 964.0
RFC5 1409 3528.0
RFWD2 2172 -2186.0
RHNO1 -4573 -113.0
RMI1 4517 -56.0
RMI2 -2759 -5106.0
RNF168 4346 884.0
RNF8 975 -354.0
RPA1 -1837 -4231.0
RPA2 2889 -1373.0
RPA3 2702 -1706.0
RPS27A 783 1840.0
RSF1 951 554.0
RUVBL1 -1240 372.0
RUVBL2 -2543 -803.0
SDCCAG8 1021 3590.0
SEC13 730 1702.0
SEH1L 1085 4263.0
SET 3683 2131.0
SFI1 -1212 -2485.0
SHQ1 3320 2920.0
SIRT2 -4852 -11.0
SKA2 2399 907.0
SKP1 2028 -2504.0
SKP2 4205 4385.0
SMARCA5 4439 2255.0
SMC1A 3824 -810.0
SMC2 2477 3769.0
SMC3 4878 2878.0
SMC4 4127 1098.0
SPAST 3456 -3172.0
SRC -3910 1378.0
SSNA1 -2879 -732.0
STAG1 4246 -1940.0
STAG2 31 -4179.0
STRA13 -1061 -1709.0
SUMO1 4213 1399.0
SUN1 -4018 -2921.0
SUN2 -5310 -5062.0
SYNE1 -4982 526.0
SYNE2 1402 -4474.0
TAOK1 1644 -3805.0
TERF1 422 16.0
TERF2 -1834 1195.0
TERF2IP 4692 -1399.0
TFDP1 -2245 -2659.0
TFDP2 4029 -5361.0
TINF2 -1257 1757.0
TK1 -3225 906.0
TMPO 4574 335.0
TNPO1 3184 5129.0
TOP2A 4691 4445.0
TOP3A 2607 1632.0
TOPBP1 2183 4567.0
TP53 575 3751.0
TP53BP1 -643 3904.0
TPR 2984 -1026.0
TPX2 3446 2359.0
TUBA1A -5228 3715.0
TUBA1B -5324 4914.0
TUBA1C -4883 5125.0
TUBA4A -5342 2072.0
TUBA8 -1116 -888.0
TUBB -3118 5070.0
TUBB2A -4676 4448.0
TUBB2B -4704 4960.0
TUBB4B 430 4896.0
TUBB6 -5060 5204.0
TUBG1 -3728 328.0
TUBG2 93 -164.0
TUBGCP2 -3362 -2965.0
TUBGCP3 2352 1674.0
TUBGCP4 4074 1827.0
TUBGCP6 -3953 -3026.0
TYMS -2042 2614.0
UBC 2672 4480.0
UBE2C 4949 463.0
UBE2D1 -1588 -4032.0
UBE2E1 -1132 -479.0
UBE2I 1246 1214.0
UBE2N 2545 3996.0
UBE2S 4441 4268.0
UBE2V2 -334 1298.0
UIMC1 835 -375.0
USO1 -738 1516.0
VPS4A -1545 -2086.0
VRK1 1696 -959.0
VRK2 1461 -2309.0
WEE1 -4561 1755.0
WRAP53 1081 593.0
WRN 98 2665.0
XPO1 990 1809.0
YWHAB 3680 3415.0
YWHAE 1394 -914.0
YWHAG -2372 -3104.0
YWHAH -2777 4700.0
YWHAQ 963 3739.0
YWHAZ 2019 4495.0
ZNF385A -5211 4005.0
ZW10 1474 1263.0
ZWINT 2778 5161.0



Immune System

Immune System
metric value
setSize 1225
pMANOVA 1.08e-14
p.adjustMANOVA 8.9e-13
s.dist 0.135
s.human -0.0241
s.mouse 0.132
p.human 0.169
p.mouse 4.1e-14




Top 20 genes
Gene human mouse
SERPINB6 -5411 4903
FBXO40 -5485 4684
CDKN1A -4927 5092
PFKL -4966 4932
SIRPA -5627 4222
VCL -4538 5034
ASB12 -4251 5187
DUSP2 -4253 5104
KIF2A -4390 4818
ANXA2 -4123 5025
MID1 -4726 4300
LIMK1 -4857 4174
STAT3 -3885 5061
GDNF -4043 4741
PPIA -4031 4697
ALDH3B1 -4529 4142
CSF1 -4242 4358
EDA2R -4901 3755
TRIM62 -4984 3681
MSN -3907 4668

Click HERE to show all gene set members

All member genes
human mouse
AAAS -3476.0 1550.0
AAMP 2657.0 111.0
ABCE1 4707.0 572.0
ABHD17A -1525.0 -161.0
ABHD17B 1639.0 1020.0
ABHD17C -2092.0 2958.0
ABI1 3792.0 2553.0
ABI2 -308.0 5048.0
ABL1 -4533.0 -3545.0
ACLY -2628.0 3492.0
ACTB 940.0 4977.0
ACTG1 -3075.0 4986.0
ACTN2 -3104.0 3454.0
ACTR10 1853.0 897.0
ACTR1A -4126.0 1651.0
ACTR1B -4206.0 3803.0
ACTR2 3547.0 3933.0
ACTR3 1376.0 5136.0
ADAM10 -1509.0 -1025.0
ADAM17 2407.0 2079.0
ADAM8 -2592.0 5107.0
ADAR -3014.0 420.0
AGA 1618.0 -4995.0
AGL -4967.0 -5094.0
AGPAT2 -4979.0 -2002.0
AHCYL1 -3386.0 988.0
AIP -707.0 -1563.0
AKT1 -4954.0 342.0
AKT2 -4057.0 -4450.0
AKT3 1343.0 -320.0
ALAD -3855.0 -3630.0
ALDH3B1 -4529.0 4142.0
ALDOA -5575.0 -3482.0
ALDOC 1379.0 4707.0
ALPK1 -1737.0 -234.0
AMPD3 -4286.0 4079.0
ANAPC1 572.0 -4087.0
ANAPC10 1974.0 2134.0
ANAPC11 -3265.0 -1751.0
ANAPC13 -1663.0 -2732.0
ANAPC2 -2185.0 -3532.0
ANAPC4 -720.0 -4834.0
ANAPC5 1284.0 -2104.0
ANAPC7 1595.0 2349.0
ANGPT1 -853.0 -4174.0
ANO6 -4134.0 2564.0
ANPEP -215.0 -634.0
ANXA1 537.0 4544.0
ANXA2 -4123.0 5025.0
AP1B1 -4552.0 -34.0
AP1G1 4140.0 2569.0
AP1M1 3732.0 1437.0
AP1S1 -1410.0 812.0
AP1S2 -1634.0 1536.0
AP2A1 -3632.0 -420.0
AP2A2 -1058.0 5063.0
AP2B1 -1157.0 2251.0
AP2M1 -2746.0 3372.0
AP2S1 1777.0 1981.0
APAF1 -3469.0 2921.0
APEH -3390.0 -1366.0
APP -2792.0 582.0
APRT -3384.0 -51.0
ARAF -3318.0 -4367.0
AREL1 4938.0 -1959.0
ARF1 566.0 4500.0
ARHGAP9 -2941.0 2431.0
ARIH1 4268.0 2886.0
ARIH2 -567.0 -2166.0
ARL2 -4142.0 -523.0
ARL8A -4586.0 3346.0
ARMC8 -194.0 -4059.0
ARPC1A -120.0 2648.0
ARPC1B 669.0 4856.0
ARPC2 1357.0 4617.0
ARPC3 2873.0 3762.0
ARPC4 1698.0 2568.0
ARPC5 2295.0 4844.0
ARRB1 -3133.0 -14.0
ARRB2 -1089.0 4317.0
ARSA -3312.0 1530.0
ARSB -1001.0 2832.0
ART1 -5553.0 -4799.0
ASAH1 -3414.0 5051.0
ASB1 -3550.0 -3059.0
ASB10 -4350.0 -4854.0
ASB11 -3603.0 2420.0
ASB12 -4251.0 5187.0
ASB13 -4486.0 -4974.0
ASB14 -3742.0 -5042.0
ASB15 -3072.0 -4545.0
ASB16 -4432.0 -5109.0
ASB18 1023.0 -5310.0
ASB2 -4929.0 -4415.0
ASB4 -94.0 -4156.0
ASB5 -2529.0 4549.0
ASB6 1361.0 4073.0
ASB7 2584.0 -2041.0
ASB8 2095.0 -4650.0
ATAD3B 1907.0 -4078.5
ATF1 3129.0 3014.0
ATF2 3130.0 1863.0
ATG12 4060.0 1590.0
ATG5 1661.0 1956.0
ATG7 -1364.0 1374.0
ATOX1 646.0 433.0
ATP11A -1843.0 -4608.0
ATP11B 4841.0 -2179.0
ATP6AP2 2114.0 5158.0
ATP6V0A1 -3809.0 1763.0
ATP6V0A2 186.0 -2715.0
ATP6V0B -3461.0 664.0
ATP6V0D1 -2256.0 4236.0
ATP6V0E1 1861.0 4262.0
ATP6V0E2 -1727.0 -2952.0
ATP6V1A 1633.0 729.0
ATP6V1B2 2299.0 4678.0
ATP6V1C1 3521.0 5003.0
ATP6V1D 3269.0 -2868.0
ATP6V1E1 3913.0 -407.0
ATP6V1F -3562.0 -2379.0
ATP6V1G2 1570.0 -473.0
ATP6V1H -57.0 4488.0
ATP7A 1448.0 -287.0
ATP8A1 1830.0 -3788.0
B2M -731.0 1593.0
B4GALT1 -1314.0 2589.0
BAIAP2 -641.0 5041.0
BCL10 4124.0 4239.0
BCL2 -4633.0 -1108.0
BCL2L1 -5181.0 3434.0
BCL6 -5018.0 -4816.0
BIRC2 3739.0 -2890.0
BIRC3 -4741.0 978.0
BLMH -3217.0 694.0
BRAF 4103.0 1387.0
BRAP 4689.0 3899.0
BRI3 -3525.0 -1234.0
BRK1 2026.0 3096.0
BRWD1 2271.0 -4063.0
BTBD1 -2710.0 -3858.0
BTBD6 -5281.0 -768.0
BTRC -1187.0 -2758.0
C1R -813.0 -1019.0
C1S -2427.0 -2050.0
C2 -558.0 -1359.0
C3 4311.0 1838.0
C6orf120 1881.0 2354.0
C7 -1128.0 1335.0
CAB39 2485.0 2704.0
CALM1 -4464.0 96.0
CALR 1534.0 4995.0
CAMK2A -5527.0 -4430.0
CAMK2B -5497.0 -4230.0
CAMK2D -2223.0 4137.0
CAMK2G -2097.0 -4962.0
CAND1 3370.0 4369.0
CANT1 511.0 1963.0
CANX -836.0 4736.0
CAP1 2590.0 4328.0
CAPN1 -5166.0 -4425.0
CAPZA2 -1777.0 -3734.0
CAPZB -3165.0 -2667.0
CASP1 -1298.0 3173.0
CASP2 2946.0 -3849.0
CASP3 423.0 5016.0
CASP8 -1646.0 3092.0
CASP9 -3269.0 -2569.0
CAT -4828.0 -4266.0
CBL 1736.0 183.0
CBLB -3482.0 1312.0
CCL2 2620.0 5111.0
CCND1 757.0 529.0
CCNF 3488.0 3821.0
CCT2 3805.0 4207.0
CCT8 4149.0 3796.0
CD274 3395.0 -1973.0
CD28 -2910.0 -5023.0
CD34 858.0 891.0
CD36 -582.0 -3838.0
CD44 837.0 4987.0
CD46 1543.0 -3487.0
CD47 -2184.0 2680.0
CD55 220.0 -323.0
CD59 1637.0 -4378.0
CD63 -3297.0 4594.0
CD81 -4675.0 895.0
CDC16 86.0 -1984.0
CDC23 3850.0 -1171.0
CDC26 2750.0 2457.0
CDC27 665.0 1230.0
CDC34 -2923.0 -2346.0
CDC42 3308.0 754.0
CDK13 4123.0 1830.0
CDKN1A -4927.0 5092.0
CEP290 3352.0 -4522.0
CFH -556.0 -115.0
CFL1 -909.0 4720.0
CHUK 216.0 955.0
CKAP4 -3818.0 4639.0
CLCF1 -2419.0 2301.0
CLTA 1218.0 1668.0
CLTC 2268.0 -2802.0
CLU 1629.0 4164.0
CMTM6 2331.0 4071.0
CNKSR1 -2870.0 3756.0
CNN2 -4870.0 2117.0
CNPY3 -3045.0 3021.0
COL1A2 -1712.0 -377.0
COLEC12 4261.0 45.0
COMMD3 246.0 -1247.0
COMMD9 385.0 1630.0
COPB1 3916.0 4572.0
COTL1 -1553.0 5172.0
CPNE3 1228.0 -3452.0
CPPED1 -3625.0 -4900.0
CRCP 1806.0 -883.0
CREB1 2179.0 -4329.0
CREBBP 1506.0 3139.0
CREG1 1430.0 -1124.0
CRISPLD2 -871.0 -3137.0
CRK 2145.0 2262.0
CRKL -91.0 4314.0
CRLF1 42.0 1779.0
CSF1 -4242.0 4358.0
CSK -3610.0 4738.0
CSNK2B 1917.0 -296.0
CSTB -3426.0 4748.0
CTF1 -3242.0 -4624.0
CTNNB1 1714.0 -780.0
CTSA -3537.0 -2181.0
CTSB -1198.0 -795.0
CTSC 2720.0 2417.0
CTSD -4817.0 -4037.0
CTSF -1942.0 -4970.0
CTSH -3465.0 3123.0
CTSK 2.0 263.0
CTSO -774.0 -1570.0
CTSS -339.0 5084.0
CTSV 2209.0 34.0
CTSZ -3890.0 3389.0
CUL1 -3121.0 -1536.0
CUL2 4097.0 -3317.0
CUL3 2833.0 -224.0
CUL5 2599.0 -3195.0
CUL7 -4939.0 448.0
CYB5R3 -5395.0 3330.0
CYBA -633.0 3083.0
CYBB -2550.0 3579.0
CYFIP2 -3775.0 -1129.0
CYLD -1990.0 2392.0
CYSTM1 -1304.0 1985.0
DAB2IP -5036.0 810.0
DAPP1 4539.0 3051.0
DBNL -2320.0 4579.0
DCTN1 -347.0 -2402.0
DCTN2 -3157.0 -448.0
DCTN3 -943.0 2888.0
DCTN4 613.0 242.0
DCTN5 2557.0 1793.0
DCTN6 1852.0 -2191.0
DDOST 320.0 4699.0
DDX3X 4686.0 4170.0
DDX41 273.0 705.0
DDX58 1593.0 -909.0
DEGS1 -2228.0 3767.0
DERA 3823.0 1200.0
DET1 -2613.0 -2540.0
DGAT1 -2804.0 -1001.0
DHX36 3822.0 -3595.0
DHX58 -2934.0 1196.0
DHX9 4151.0 322.0
DIAPH1 3282.0 5032.0
DLG1 -52.0 918.0
DLG3 -1567.0 -2178.0
DLG4 -1594.0 364.0
DNAJC13 1888.0 -3638.0
DNAJC3 1950.0 1334.0
DNAJC5 -2830.0 1053.0
DNASE1L1 -5205.0 -5289.0
DNM1 -747.0 1193.0
DNM2 -1149.0 2166.0
DNM3 4865.0 -1268.0
DOCK1 -226.0 -41.0
DOK3 -5498.0 3093.0
DPP7 -4199.0 2087.0
DSN1 2075.0 534.0
DTX3L -702.0 -4304.0
DTX4 4372.0 -2645.0
DUSP1 -219.0 4494.0
DUSP10 -5329.0 2114.0
DUSP16 3082.0 2356.0
DUSP2 -4253.0 5104.0
DUSP3 -5149.0 -5173.0
DUSP4 -3613.0 3013.0
DUSP5 4084.0 5213.0
DUSP6 -528.0 -1256.0
DUSP7 -3477.0 -3537.0
DUSP8 1715.0 4654.0
DYNC1H1 -1442.0 -2348.0
DYNC1I2 2591.0 -2971.0
DYNC1LI1 2883.0 1316.0
DYNC1LI2 1750.0 -1620.0
DYNLL1 -1331.0 4245.0
DYNLT1 2579.0 1650.0
DZIP3 336.0 76.0
ECSIT -2655.0 -2846.0
EDA -124.0 1970.0
EDA2R -4901.0 3755.0
EEA1 1370.0 1624.0
EEF1A1 -2150.0 2931.0
EEF2 -2853.0 -853.0
EGF -4568.0 -5354.0
EGFR 424.0 1475.0
EGR1 4164.0 5238.0
EIF2AK2 -486.0 -749.0
EIF4A1 2916.0 5133.0
EIF4A2 1360.0 1839.0
EIF4A3 4491.0 3824.0
EIF4E 2892.0 3735.0
EIF4E2 -2440.0 3158.0
EIF4E3 -2251.0 -1876.0
EIF4G1 -2988.0 -4223.0
EIF4G2 1963.0 -554.0
EIF4G3 -2799.0 -3576.0
ELK1 -3862.0 -42.0
ELMO1 -2166.0 1449.0
ELMO2 -354.0 416.0
ENAH 4332.0 5242.0
ENPP4 -1280.0 -3299.0
EP300 3403.0 -1622.0
ERAP1 -1974.0 -2256.0
ERBB2 -5511.0 673.0
ERBB3 -5290.0 -2790.0
ERP44 2150.0 2698.0
EVL -3566.0 2476.0
F13A1 -2059.0 3642.0
FABP5 -338.0 -519.0
FADD -571.0 4877.0
FAF2 3890.0 3211.0
FBXL12 4384.0 -2619.0
FBXL14 2633.0 2822.0
FBXL15 -1080.0 2107.0
FBXL16 -1561.0 1534.0
FBXL18 1610.0 -2831.0
FBXL19 1130.0 2485.0
FBXL20 2822.0 -4508.0
FBXL22 -4906.0 441.0
FBXL3 3227.0 604.0
FBXL4 2514.0 -3018.0
FBXL5 2542.0 251.0
FBXL8 -1774.0 2599.0
FBXO10 -5271.0 -388.0
FBXO11 -962.0 -2029.0
FBXO17 -3932.0 920.0
FBXO21 -481.0 -4656.0
FBXO22 -1604.0 -439.0
FBXO30 2102.0 3729.0
FBXO31 -4655.0 -4554.0
FBXO32 -4380.0 -4921.0
FBXO4 -1189.0 2918.0
FBXO40 -5485.0 4684.0
FBXO44 -2981.0 -3704.0
FBXO6 3598.0 -3648.0
FBXO7 375.0 -1377.0
FBXO9 -1473.0 -5128.0
FBXW11 4385.0 4535.0
FBXW2 -2282.0 -1687.0
FBXW4 -4330.0 -1287.0
FBXW5 -4784.0 -4258.0
FBXW7 -886.0 -330.0
FBXW8 -2816.0 888.0
FBXW9 -1076.0 1911.0
FGF1 798.0 5215.0
FGF2 751.0 -1095.0
FGF7 -5445.0 2606.0
FGF9 -5320.0 -3468.0
FGFR1 -1499.0 -3421.0
FGFR3 3759.0 4128.0
FGFR4 -5312.0 -3374.0
FGL2 -1862.0 3038.0
FLNA -3248.0 3245.0
FLNB 2772.0 1024.0
FN1 35.0 4022.0
FNTA 1578.0 -1804.0
FNTB -690.0 2634.0
FOS 1865.0 5273.0
FOXO1 -432.0 1302.0
FOXO3 -42.0 -1131.0
FRK 194.0 -2049.0
FRS2 4678.0 761.0
FRS3 1398.0 1971.0
FSCN1 1705.0 -932.0
FTH1 -1890.0 -127.0
FUCA1 111.0 1320.0
FUCA2 -2160.0 -4180.0
FYB -2235.0 3488.0
FYN -2850.0 3685.0
FZR1 -1244.0 3620.0
GAA -5001.0 -3369.0
GAB1 -1853.0 -2427.0
GAB2 4053.0 2422.0
GALNS -3960.0 4545.0
GBP6 -2110.0 -3927.0
GCA 2461.0 -4105.0
GDI2 865.0 4849.0
GDNF -4043.0 4741.0
GFRA1 -4438.0 -2997.0
GGH 3482.0 1046.0
GHDC -3542.0 -4089.0
GHR 3997.0 -4645.0
GLA 3418.0 -1853.0
GLB1 -2244.0 924.0
GLMN 4722.0 72.0
GM2A -1169.0 2670.0
GNS 101.0 -979.0
GOLGA7 1185.0 2077.0
GPI -5210.0 -4132.0
GRB2 -4050.0 4496.0
GRN -4029.0 2537.0
GSDMD -2517.0 3392.0
GSN 72.0 -256.0
GSTO1 -2055.0 -2038.0
GUSB 1923.0 4153.0
GYG1 -3875.0 4435.0
HACE1 374.0 -846.0
HBEGF 3484.0 5272.0
HECTD1 1958.0 -5224.0
HECTD2 -3544.0 2296.0
HECTD3 -519.0 -4034.0
HECW2 -1074.0 -2124.0
HERC1 -3474.0 -4858.0
HERC3 1164.0 2071.0
HERC4 1215.0 4038.0
HERC6 168.0 -2222.0
HEXB 753.0 2379.0
HGSNAT -4600.0 -3529.0
HIF1A -1016.0 5007.0
HLA-DMA 1128.0 4727.0
HMGB1 -2199.0 -1662.0
HMOX1 -2843.0 5071.0
HMOX2 -687.0 552.0
HNRNPA2B1 3693.0 -2053.0
HNRNPF 4978.0 4644.0
HRAS -4545.0 -3997.0
HSP90AA1 3656.0 5261.0
HSP90AB1 -639.0 4629.0
HSP90B1 460.0 4944.0
HSPA1A 4887.0 5277.5
HSPA1B 4676.0 5277.5
HSPA5 2574.0 5200.0
HSPA8 3674.0 5088.0
HSPA9 2342.0 -1431.0
HUWE1 -673.0 -4013.0
HVCN1 -2318.0 -2383.0
ICAM1 1056.0 4172.0
ICAM2 -1505.0 -3478.0
ICMT -2315.0 -1731.0
IDH1 1160.0 -5189.0
IFI16 -1127.0 4923.5
IFI27 -1101.0 -399.0
IFI35 -3310.0 174.0
IFIH1 -204.0 -3116.0
IFIT2 -1338.0 802.0
IFIT3 -792.0 1422.0
IFITM1 1574.0 4815.0
IFITM2 -316.0 4815.0
IFITM3 380.0 4815.0
IFNAR1 3645.0 1085.0
IFNAR2 -1316.0 2360.0
IFNGR1 2506.0 2475.0
IFNGR2 -386.0 -4286.0
IGF2R -2030.0 -1074.0
IKBKB -4093.0 578.0
IL10RB 1239.0 3244.0
IL11RA -5610.0 -2978.0
IL13RA1 -1847.0 4516.0
IL15 -2409.0 -2685.0
IL16 -1613.0 -1365.0
IL17RA 219.0 4833.0
IL17RC -4271.0 1044.0
IL17RD -3179.0 -934.0
IL17RE -1865.0 -4593.0
IL18BP 292.0 2178.0
IL1R1 -3018.0 3910.0
IL1RAP 627.0 3712.0
IL20RB -159.0 -902.0
IL2RG -1943.0 3730.0
IL33 1864.0 3608.0
IL34 3060.0 -1540.0
IL4R -3335.0 4935.0
IL6R -5515.0 3267.0
IL6ST 3055.0 -2364.0
ILF2 4835.0 4254.0
IMPDH1 -827.0 2546.0
IMPDH2 822.0 1907.0
INPP5D -2433.0 4327.0
INPPL1 -5220.0 -4249.0
IP6K2 3404.0 -661.0
IQGAP1 -415.0 3217.0
IRAK1 -4351.0 -480.0
IRAK2 -4255.0 3633.0
IRAK3 95.0 1688.0
IRAK4 -569.0 1975.0
IRF1 -1565.0 984.0
IRF2 -3387.0 2261.0
IRF3 -3061.0 -114.0
IRF4 -1166.0 2585.0
IRF7 775.0 4030.0
IRF9 1267.0 132.0
IRS1 -5550.0 -5121.0
IRS2 3384.0 2684.0
ISG15 -3928.0 1737.0
IST1 3827.0 4131.0
ITCH 4319.0 -2959.0
ITGA4 -2878.0 -5141.0
ITGAM -2633.0 5045.0
ITGAV -819.0 50.0
ITGAX -896.0 3851.0
ITGB1 956.0 4614.0
ITGB2 -107.0 4993.0
ITGB3 -488.0 4915.0
ITGB5 -2578.0 -4797.0
ITPR1 4903.0 -2230.0
ITPR2 1242.0 -3115.0
ITPR3 -3631.0 -3441.0
JAK1 -1869.0 4228.0
JAK2 -2569.0 -5057.0
JUN 2469.0 5225.0
JUNB -2593.0 5221.0
JUP 1723.0 4368.0
KBTBD7 1566.0 3587.0
KBTBD8 4994.0 4291.0
KCMF1 501.0 -1005.0
KCNAB2 -3198.0 5020.0
KCTD6 2748.0 3456.0
KCTD7 -1996.0 -1428.5
KEAP1 -1297.0 -4420.0
KIF11 2319.0 4310.0
KIF18A 3832.0 4144.0
KIF23 1216.0 4134.0
KIF2A -4390.0 4818.0
KIF3A 4718.0 1513.0
KIF3B 3571.0 1699.0
KIF3C -3766.0 -4729.0
KIF5A 4430.0 731.0
KIF5B 838.0 1727.0
KIF5C 4658.0 -750.0
KIFAP3 -1339.0 -4750.0
KITLG 4898.0 -4811.0
KLC1 -3922.0 2366.0
KLC2 -1732.0 -2589.0
KLC4 -3559.0 -1292.0
KLHL11 788.0 99.0
KLHL13 -4145.0 446.0
KLHL2 624.0 2197.0
KLHL20 3341.0 -3971.0
KLHL21 -3865.0 -4633.0
KLHL22 -4107.0 -3046.0
KLHL25 -2113.0 2656.0
KLHL3 -3824.0 -4229.0
KLHL41 -2822.0 5232.0
KLHL42 -441.0 -4171.0
KLHL5 4206.0 -204.0
KLHL9 4740.0 -677.0
KPNA1 1833.0 3439.0
KPNA2 5007.0 3593.0
KPNA3 -2337.0 -1621.0
KPNA4 1501.0 4518.0
KPNB1 3619.0 3517.0
KRAS 3546.0 4454.0
KSR1 -5578.0 -5013.0
LAMA5 -5584.0 -2744.0
LAMP1 764.0 -2637.0
LAMP2 -2579.0 848.0
LAMTOR1 -800.0 -2671.0
LAMTOR2 -1715.0 -424.0
LAMTOR3 3134.0 3162.0
LAT2 -1020.0 4497.0
LGALS3 1062.0 4809.0
LGMN 4834.0 4463.0
LIFR -994.0 -4795.0
LIMK1 -4857.0 4174.0
LMNB1 3392.0 2947.0
LMO7 -3084.0 -2763.0
LNPEP 463.0 -1555.0
LNX1 -4202.0 3397.0
LONRF1 672.0 -2047.0
LPCAT1 -1659.0 2005.0
LRRC41 -4474.0 3913.0
LRRFIP1 -4175.0 -4627.0
LRSAM1 -4650.0 -4407.0
LTA4H 1584.0 4089.0
LTBR -4989.0 1241.0
LTN1 4960.0 -4075.0
LYN 785.0 3984.0
LYPLA1 1177.0 -3760.0
MAGT1 1192.0 -1341.0
MALT1 -2616.0 -3568.0
MAN2B1 -3000.0 331.0
MANBA -1928.0 -2694.0
MAOA -96.0 3927.0
MAP2K1 -506.0 -2643.0
MAP2K2 -3813.0 -1797.0
MAP2K3 -4716.0 3039.0
MAP2K4 8.0 -3251.0
MAP2K6 1456.0 -4876.0
MAP2K7 794.0 -3887.0
MAP3K1 1124.0 -3440.0
MAP3K11 -3624.0 1948.0
MAP3K3 2825.0 757.0
MAP3K7 2142.0 -4056.0
MAP3K8 344.0 4159.0
MAPK1 1988.0 -648.0
MAPK10 -3504.0 -1859.0
MAPK11 -3385.0 -333.0
MAPK12 -5264.0 644.0
MAPK14 -1562.0 -1635.0
MAPK3 -1024.0 3725.0
MAPK7 -729.0 3565.0
MAPK8 457.0 1106.0
MAPK9 -3854.0 -3511.0
MAPKAP1 -405.0 2624.0
MAPKAPK2 -2489.0 -645.0
MAPKAPK3 -4795.0 -3142.0
MARK3 3178.0 -2043.0
MASP1 -4224.0 -1589.0
MAVS -4768.0 -4861.0
MCL1 2837.0 4826.0
MEF2A -5175.0 -4103.0
MEF2C -4610.0 -2794.0
MET -3529.0 2929.0
METTL7A -5605.0 -5247.0
MEX3C 4035.0 5004.0
MGRN1 -3720.0 -1386.0
MGST1 427.0 -2546.0
MIB2 -4266.0 698.0
MID1 -4726.0 4300.0
MIF -2307.0 2943.0
MKRN1 2493.0 2062.0
MLEC -3173.0 -5166.0
MLST8 -3485.0 -2266.0
MME -3346.0 -3103.0
MMP2 -692.0 -2003.0
MOSPD2 3720.0 -2512.0
MRAS -5239.0 941.0
MRC2 -970.0 2118.0
MSN -3907.0 4668.0
MTAP -2515.0 -2196.0
MTOR -1191.0 -1922.0
MVP -4506.0 2829.0
MX1 -1867.0 3219.0
MYC 3994.0 4886.0
MYD88 2726.0 4679.0
MYH2 -3080.0 -857.0
MYH9 -1879.0 4194.0
MYLIP -4026.0 -2114.0
MYO10 1381.0 294.0
MYO1C -4842.0 3521.0
MYO5A -885.0 3279.0
MYO9B -1901.0 4055.0
NBEAL2 -4727.0 -339.0
NCAM1 -3954.0 4132.0
NCK1 3718.0 1288.0
NCKAP1 3563.0 3585.0
NCKIPSD -2821.0 704.0
NCSTN -2504.0 1262.0
NDC1 1273.0 -2350.0
NDN 1146.0 1877.0
NDUFC2 34.0 -2430.0
NEDD4 4583.0 -4838.0
NEDD4L 4279.0 -2158.0
NEU1 1863.0 4218.0
NF1 3095.0 3333.0
NF2 -1449.0 -4728.0
NFASC -2394.0 602.0
NFATC1 -5337.0 -1304.0
NFATC2 -3264.0 3355.0
NFATC3 -3321.0 -2944.0
NFKB1 -4233.0 3315.0
NFKB2 -3926.0 3336.0
NFKBIA -4263.0 4096.0
NFKBIB 4450.0 3578.0
NFKBIE -4165.0 2873.0
NHLRC3 -3747.0 2370.0
NIT2 -1606.0 -943.0
NKIRAS1 4369.0 -2967.0
NKIRAS2 -1369.0 2403.0
NLRC3 -2924.0 1084.0
NLRC5 -4398.0 2653.0
NLRX1 -4825.0 -4899.0
NOD1 -3886.0 -3144.0
NOD2 -4402.0 1776.0
NOS1 -4260.0 -4935.0
NPC2 790.0 2258.0
NPDC1 -2124.0 1835.0
NPEPPS 44.0 -2563.0
NRAS 4354.0 69.0
NUP107 3232.0 2949.0
NUP133 889.0 -4048.0
NUP153 4762.0 1533.0
NUP155 4306.0 -2233.0
NUP160 3998.0 1035.0
NUP188 2117.0 3830.0
NUP205 4438.0 3588.0
NUP214 3124.0 665.0
NUP35 4571.0 649.0
NUP37 -327.0 192.0
NUP43 4562.0 2216.0
NUP54 4508.0 3831.0
NUP85 3181.0 -393.0
NUP88 1244.0 2212.0
NUP93 -1503.0 3903.0
NUP98 4235.0 5066.0
OAS2 212.0 2064.0
ORAI2 936.0 811.0
ORMDL3 893.0 3912.0
OSBPL1A -2961.0 -4807.0
OSMR 255.0 4589.0
OSTF1 2228.0 2902.0
OTUD5 4179.0 2823.0
P4HB -2525.0 4048.0
PADI2 -5625.0 -4599.0
PAFAH1B2 3709.0 4387.0
PAG1 -2006.0 851.0
PAK1 -5419.0 -4885.0
PAK2 1525.0 4805.0
PANX1 1142.0 1062.0
PAQR3 396.0 3865.0
PARK2 -4936.0 -960.0
PDAP1 -1236.0 1825.0
PDCD4 2217.0 1037.0
PDE12 4844.0 3597.0
PDE6D -2753.0 4470.0
PDGFA -4328.0 -4456.0
PDGFB -606.0 3347.0
PDGFRA 2727.0 -349.0
PDGFRB -2260.0 1386.0
PDIA3 3090.0 4989.0
PDPK1 3443.0 2222.0
PDXK -4690.0 -834.0
PDZD11 1678.0 490.0
PEA15 -1982.0 1596.0
PEBP1 -3678.0 -1052.0
PELI1 4489.0 4759.0
PELI2 3371.0 -1012.0
PELI3 -4396.0 795.0
PFKL -4966.0 4932.0
PGM1 -4270.0 -4493.0
PGM2 -561.0 3964.0
PGRMC1 -333.0 1308.0
PHB -586.0 -2116.0
PIAS1 57.0 -2190.0
PIK3AP1 966.0 3680.0
PIK3C3 3439.0 -1648.0
PIK3CA 365.0 2811.0
PIK3CB 2760.0 4994.0
PIK3CD -4322.0 -4161.0
PIK3R1 2896.0 -3147.0
PIK3R3 3188.0 577.0
PIK3R4 3839.0 -3531.0
PIM1 -228.0 4294.0
PIN1 -3515.0 1213.0
PITPNA -2450.0 -694.0
PJA1 1991.0 -2150.0
PJA2 397.0 -2473.0
PKM -4231.0 -4264.0
PLA2G6 -3913.0 -525.0
PLAU -548.0 1192.0
PLAUR -638.0 3744.0
PLCG1 -3955.0 -4939.0
PLD1 55.0 -779.0
PLD2 -60.0 -4810.0
PLD3 -5217.0 573.0
PLEKHO2 -717.0 3402.0
PML 3338.0 3449.0
PNP 5019.5 4586.0
POLR1C 3643.0 4119.0
POLR1D 413.0 1462.0
POLR2E -667.0 1599.0
POLR2H -3927.0 3497.0
POLR2K 2480.0 -1584.0
POLR2L -4314.0 4110.0
POLR3A 4348.0 -4076.0
POLR3B 2547.0 -3390.0
POLR3C 4052.0 3012.0
POLR3D 381.0 1468.0
POLR3E 1908.0 -1229.0
POLR3F 4054.0 2443.0
POLR3G 1455.0 3367.0
POLR3GL -1424.0 -3192.0
POLR3H 282.0 2294.0
POLR3K 4716.0 -3105.0
POU2F1 3019.0 -3333.0
PPIA -4031.0 4697.0
PPIE 2144.0 896.0
PPL -2270.0 30.0
PPM1B 4912.0 1319.0
PPP1CB -1374.0 -4149.0
PPP1CC 4081.0 399.0
PPP2CA 4482.0 3008.0
PPP2CB 2458.0 4129.0
PPP2R1A -4013.0 -696.0
PPP2R1B 3028.0 4619.0
PPP2R5A 4590.0 4219.0
PPP2R5B -1524.0 121.0
PPP2R5C -2508.0 -3684.0
PPP2R5D -3449.0 -2058.0
PPP2R5E 4644.0 1539.0
PPP3CA 109.0 -2737.0
PPP3CB -3435.0 -5065.0
PPP5C -4582.0 -1815.0
PRCP 970.0 870.0
PRDX4 132.0 2521.0
PRDX6 -3481.0 4973.0
PRKACA -4691.0 -1606.0
PRKACB -2659.0 -1546.0
PRKCD -4276.0 3377.0
PRKCE -4307.0 -3088.0
PRKCQ -5095.0 -4882.0
PRKCSH -268.0 539.0
PRKDC 2294.0 -3033.0
PRKG1 1401.0 5121.0
PROS1 103.0 2938.0
PRR5 -837.0 422.0
PSAP -2247.0 -4040.0
PSEN1 2070.0 2061.0
PSMA1 2820.0 3328.0
PSMA3 3434.0 -4.0
PSMA4 769.0 958.0
PSMA6 2199.0 -1044.0
PSMA7 -2980.0 976.0
PSMB1 954.0 2628.0
PSMB10 -1800.0 2907.0
PSMB2 618.0 2471.0
PSMB4 -235.0 2096.0
PSMB5 -4113.0 -606.0
PSMB6 -793.0 914.0
PSMB7 -831.0 -1453.0
PSMB8 -675.0 2066.0
PSMB9 -1611.0 -2973.0
PSMC1 449.0 -336.0
PSMC2 -1311.0 3241.0
PSMC3 -2439.0 -369.0
PSMC4 2724.0 1416.0
PSMC5 1212.0 -1123.0
PSMC6 -2520.0 3423.0
PSMD1 2619.0 -1191.0
PSMD10 -1227.0 525.0
PSMD11 995.0 5183.0
PSMD12 3831.0 536.0
PSMD13 821.0 1665.0
PSMD14 -635.0 3816.0
PSMD2 -713.0 -555.0
PSMD3 -3343.0 2226.0
PSMD4 -214.0 2558.0
PSMD5 1807.0 3558.0
PSMD6 3537.0 -2207.0
PSMD7 -2329.0 1233.0
PSMD8 -3171.0 4626.0
PSMD9 4204.0 -970.0
PSME1 -2771.0 3350.0
PSME2 -4085.0 3584.0
PSME3 3333.0 3379.0
PSME4 1960.0 -4574.0
PSMF1 683.0 -1480.0
PTEN 2797.0 2721.0
PTGES2 -2699.0 -3434.0
PTK2 -2497.0 -1508.0
PTK2B -2461.0 3862.0
PTPN1 1531.0 4585.0
PTPN11 -1575.0 -666.0
PTPN12 4141.0 5021.0
PTPN13 4200.0 -863.0
PTPN14 1287.0 -3965.0
PTPN18 -4024.0 2425.0
PTPN2 4314.0 4306.0
PTPN22 400.0 3570.0
PTPN23 1152.0 5065.0
PTPN3 2224.0 -5244.0
PTPN4 -1408.0 3737.0
PTPN6 -931.0 4799.0
PTPN9 -1215.0 2535.0
PTPRA -402.0 3653.0
PTPRB -4654.0 -4596.0
PTPRJ 391.0 3748.0
PTX3 -1790.0 728.0
PYCARD -2810.0 4703.0
PYGB -4498.0 1915.0
PYGL -3546.0 4121.0
QPCT 250.0 4615.0
QSOX1 2045.0 2998.0
RAB10 -2646.0 -3853.0
RAB14 2341.0 -844.0
RAB18 4588.0 -4361.0
RAB24 -1792.0 -4677.0
RAB27A 169.0 1070.0
RAB31 -547.0 4084.0
RAB3A 75.0 -3951.0
RAB3D 3527.0 1980.0
RAB5B 584.0 -3464.0
RAB5C 2317.0 3393.0
RAB7A -383.0 1499.0
RAC1 2525.0 1457.0
RAC2 41.0 4946.0
RACGAP1 4239.0 3684.0
RAE1 4471.0 2389.0
RAF1 1712.0 -1646.0
RALA -1368.0 504.0
RALGDS -5190.0 -623.0
RANBP2 4470.0 -3848.0
RANBP9 4005.0 219.0
RAP1A -689.0 3710.0
RAP1B 4479.0 4565.0
RAP1GAP -894.0 -3461.0
RAP1GAP2 -1674.0 2549.0
RAP2B 3971.0 4705.0
RAP2C -983.0 -2112.0
RAPGEF1 -3992.0 3326.0
RAPGEF2 4504.0 -3856.0
RAPGEF3 108.0 -2918.0
RAPGEF4 4622.0 3189.0
RASA1 -612.0 -183.0
RASA2 3565.0 62.0
RASA3 -4990.0 -756.0
RASAL2 3510.0 -2420.0
RASGRF2 4373.0 -3165.0
RASGRP2 -2556.0 -4280.0
RASGRP3 -4774.0 -5308.0
RBBP6 5003.0 -2169.0
RBCK1 -4445.0 -4297.0
RBX1 -733.0 -968.0
RCE1 2361.0 3617.0
RCHY1 4693.0 1996.0
REL 1608.0 5022.0
RELA 1783.0 4531.0
RELB -2305.0 3391.0
RGL1 -161.0 307.0
RGL2 -4344.0 -3999.0
RHOA 539.0 4193.0
RHOG -1207.0 4926.0
RHOU -4229.0 -325.0
RICTOR 3562.0 -2934.0
RILP -4284.0 -5155.0
RIPK1 325.0 719.0
RIPK2 3609.0 4837.0
RLIM 4910.0 2662.0
RNASEL 2906.0 878.0
RNASET2 -4153.0 1724.0
RNF111 3964.0 4756.0
RNF114 722.0 -1950.0
RNF123 -5370.0 -4784.0
RNF125 3620.0 -1830.0
RNF126 1365.0 3272.0
RNF130 -3856.0 -289.0
RNF135 -3677.0 989.0
RNF138 3588.0 2168.0
RNF14 -3571.0 -4027.0
RNF144B 1106.0 -382.0
RNF19A -1550.0 3095.0
RNF19B 1703.0 5222.0
RNF213 -4087.0 -1339.0
RNF216 -4323.0 2090.0
RNF217 -5062.0 -3442.0
RNF220 -1966.0 3059.0
RNF25 3292.0 3029.0
RNF34 3719.0 -1122.0
RNF4 4630.0 5000.0
RNF41 1588.0 4940.0
RNF6 4859.0 -1660.0
RNF7 -3180.0 -2134.0
ROCK1 4876.0 -54.0
RORA -5056.0 -2699.0
RORC -5248.0 -4317.0
RPS27A 783.0 1840.0
RPS6KA1 -1481.0 -46.0
RPS6KA2 -4748.0 -5153.0
RPS6KA3 952.0 410.0
RPS6KA5 51.0 -5295.0
S100A1 -4789.0 -517.0
S100A11 -3518.0 4650.0
S1PR1 2689.0 1552.0
SAMHD1 48.0 3058.0
SAR1B 2914.0 -4240.0
SCAMP1 -549.0 1634.0
SDC1 -2046.0 212.0
SDCBP 4377.0 4839.0
SEC13 730.0 1702.0
SEC23A 3177.0 -4175.0
SEC24A 4282.0 -1165.0
SEC24B 3112.0 1867.0
SEC24C 2739.0 1614.0
SEC24D 265.0 4150.0
SEC31A 3713.0 1730.0
SEC61A1 1613.0 4608.0
SEC61A2 4702.0 -4234.0
SEC61G 2374.0 2218.0
SEH1L 1085.0 4263.0
SERPINB1 1882.0 5166.0
SERPINB6 -5411.0 4903.0
SERPING1 78.0 286.0
SH2B1 -3841.0 -971.0
SH3KBP1 1014.0 -3709.0
SH3RF1 2014.0 -840.0
SHC1 3976.0 3605.0
SHC2 -3710.0 1658.0
SHOC2 4514.0 2152.0
SIAH1 5006.0 1408.0
SIAH2 -1998.0 5216.0
SIGIRR -452.0 -1704.0
SIKE1 -73.0 -2325.0
SIPA1 -3247.0 935.0
SIRPA -5627.0 4222.0
SKP1 2028.0 -2504.0
SKP2 4205.0 4385.0
SLC15A4 -527.0 856.0
SLC2A3 5004.0 2971.5
SLC44A2 -5438.0 -4740.0
SMAD3 -3794.0 -5343.0
SMARCA4 -3874.0 -1402.0
SMURF1 4443.0 2060.0
SMURF2 1070.0 4724.0
SNAP23 372.0 -209.0
SNAP29 -2698.0 1321.0
SNRPA1 4117.0 4600.0
SOCS1 199.0 4033.0
SOCS3 -283.0 5103.0
SOCS5 4145.0 1886.0
SOD1 157.0 807.0
SOD2 -1568.0 -3943.0
SOS1 -1962.0 -1007.0
SOS2 -563.0 -3782.0
SPRED1 3312.0 3519.0
SPRED2 1200.0 -423.0
SPRED3 -2447.0 -1440.0
SPSB1 -2984.0 2447.0
SPSB2 530.0 4780.0
SPTAN1 -2425.0 -1976.0
SPTB -5499.0 -3499.0
SPTBN1 -2919.0 -3387.0
SQSTM1 -3803.0 3545.0
SRC -3910.0 1378.0
SRP14 2888.0 -1495.0
STAT1 236.0 -1738.0
STAT2 -2601.0 280.0
STAT3 -3885.0 5061.0
STAT5A -4125.0 -4573.0
STAT5B -5022.0 -5306.0
STAT6 -5317.0 -1263.0
STIM1 -3417.0 -2324.0
STK10 -3246.0 1353.0
STK11IP -451.0 -2797.0
STOM 2424.0 4434.0
STUB1 -2898.0 -690.0
STX1A -411.0 1613.0
STX3 4376.0 -2465.0
STX4 -2347.0 78.0
SUGT1 3140.0 -4533.0
SUMO1 4213.0 1399.0
SURF4 1238.0 3721.0
SVIP 3363.0 -4988.0
SYNGAP1 -3658.0 1029.0
SYNGR1 -4900.0 -5133.0
TAB1 -4874.0 -4753.0
TAB2 2791.0 681.0
TAB3 2116.0 4834.0
TALDO1 -2080.0 -766.0
TANK 3655.0 3446.0
TAP1 -4923.0 1402.0
TAP2 -1124.0 2963.0
TAPBP -3007.0 2598.0
TAX1BP1 3222.0 -1141.0
TBK1 673.0 3485.0
TCIRG1 -3600.0 4552.0
TCP1 4480.0 1210.0
TEC 3728.0 2609.0
TEK 3580.0 -2188.0
TGFB1 -3111.0 4943.0
THEM4 -3616.0 -500.0
THOP1 -3684.0 -4818.0
TICAM1 1624.0 4371.0
TIFA -1142.0 -118.0
TIMP1 -1317.0 5239.0
TIMP2 -1886.0 -738.0
TIRAP -2943.0 -3631.0
TLN1 -3918.0 2975.0
TLR3 -310.0 -3710.0
TLR4 1065.0 4916.0
TLR5 -3234.0 927.0
TLR6 888.0 1296.0
TMBIM1 -4812.0 3552.0
TMC6 -4677.0 -1324.0
TMEM30A 2855.0 -2390.0
TMEM63A -4829.0 841.0
TNFAIP3 -5203.0 1811.0
TNFAIP6 1870.0 3235.0
TNFRSF12A 1487.0 5169.0
TNFRSF14 -3195.0 -130.0
TNFRSF1A -4666.0 3362.0
TNFRSF1B -874.0 4595.0
TNFRSF25 -3839.0 -3126.0
TNFSF12 -5179.0 -2442.0
TNIP2 -1370.0 3203.0
TOLLIP -256.0 1337.0
TOM1 -5386.0 -3241.0
TP53 575.0 3751.0
TPP2 -1775.0 2534.0
TPR 2984.0 -1026.0
TRAF2 -1546.0 980.0
TRAF3 -3815.0 2462.0
TRAF6 3468.0 1207.0
TRAF7 -4038.0 2645.0
TRAIP 389.0 1014.0
TRAPPC1 368.0 -653.0
TRIB3 -1004.0 3791.0
TRIM11 2388.0 960.0
TRIM2 28.0 1777.0
TRIM21 2960.0 -747.0
TRIM25 -3243.0 -119.0
TRIM26 2745.0 1821.0
TRIM3 -1373.0 2035.0
TRIM32 1027.0 3819.0
TRIM35 3906.0 -2312.0
TRIM36 4848.0 3622.0
TRIM37 3675.0 293.0
TRIM39 2189.0 -1598.0
TRIM41 3064.0 2257.0
TRIM45 -2733.0 4282.0
TRIM5 1812.0 -4581.0
TRIM56 -3368.0 -2537.0
TRIM62 -4984.0 3681.0
TRIM63 -4866.0 -2132.0
TRIM68 3519.0 -4830.0
TRIM8 -5354.0 2384.0
TRIP12 3234.0 -4401.0
TRPC1 1744.0 -577.0
TSPAN14 -4941.0 -1469.0
TUBB -3118.0 5070.0
TUBB4B 430.0 4896.0
TWIST1 2624.0 2962.0
TXLNA -3216.0 2707.0
TXN 1855.0 4791.0
TYK2 -3123.0 -50.0
UBA1 -3060.0 1206.0
UBA3 3512.0 2083.0
UBA5 1035.0 4755.0
UBA6 3538.0 3040.0
UBA7 -1671.0 -2769.0
UBAC1 -5381.0 -2849.0
UBC 2672.0 4480.0
UBE2A -4243.0 921.0
UBE2B 1060.0 -3776.0
UBE2C 4949.0 463.0
UBE2D1 -1588.0 -4032.0
UBE2D2 -1986.0 3383.0
UBE2D3 1424.0 4934.0
UBE2E1 -1132.0 -479.0
UBE2E2 -2834.0 4459.0
UBE2E3 -4054.0 245.0
UBE2F -2462.0 1937.0
UBE2G1 -2888.0 -4986.0
UBE2G2 -2535.0 1953.0
UBE2H 2136.0 -2969.0
UBE2J1 -478.0 4007.0
UBE2J2 383.0 1756.0
UBE2K 1393.0 3662.0
UBE2L3 3051.0 -1403.0
UBE2L6 -3548.0 4613.0
UBE2M 1247.0 1561.0
UBE2N 2545.0 3996.0
UBE2O -1419.0 4366.0
UBE2Q1 -926.0 3129.0
UBE2R2 -2829.0 -2498.0
UBE2S 4441.0 4268.0
UBE2V2 -334.0 1298.0
UBE2Z 2065.0 4659.0
UBE3A 2353.0 -4652.0
UBE3B -4415.0 -4061.0
UBE3C 881.0 -1303.0
UBE3D 3787.0 -85.0
UBE4A 3862.0 -4755.0
UBOX5 -4280.0 -1643.0
UBR1 1605.0 -4949.0
UBR2 -1673.0 -4870.0
UBR4 2440.0 -3370.0
UFL1 2738.0 776.0
UNKL 442.0 -361.0
USP18 45.0 -2568.0
VAMP2 -3293.0 1812.0
VAMP3 1372.0 1400.0
VAMP7 2376.0 -4569.0
VAMP8 -2728.0 -3233.0
VAPA 2838.0 2906.0
VASP -142.0 366.0
VAT1 -4095.0 4223.0
VAV2 -4959.0 -899.0
VAV3 187.0 -1063.0
VCAM1 2866.0 4713.0
VCL -4538.0 5034.0
VEGFA -4571.0 -5196.0
VIM -3027.0 4772.0
VPRBP 847.0 1368.0
VRK3 464.0 -1371.0
VWF -779.0 -106.0
WASF2 -4656.0 1511.0
WASF3 -1015.0 718.0
WASL 2683.0 3268.0
WDR83 1010.0 -3888.0
WIPF1 -2552.0 1682.0
WIPF2 3299.0 -502.0
WIPF3 -5107.0 -5055.0
WSB1 -3737.0 4774.0
WWP1 -1200.0 -5241.0
XAF1 -320.0 -1153.0
XRCC5 4010.0 -2853.0
XRCC6 3225.0 -1241.0
YES1 -176.0 -2941.0
YPEL5 4366.0 3599.0
YWHAB 3680.0 3415.0
YWHAZ 2019.0 4495.0
ZBTB16 -4334.0 -2391.0
ZDHHC9 -3396.0 1619.0
ZEB1 -4223.0 -195.0
ZNRF1 -4109.0 1018.0
ZNRF2 -2152.0 1249.0



Signal Transduction

Signal Transduction
metric value
setSize 1401
pMANOVA 1.83e-14
p.adjustMANOVA 1.41e-12
s.dist 0.121
s.human -0.0642
s.mouse 0.102
p.human 0.000103
p.mouse 6.07e-10




Top 20 genes
Gene human mouse
TNS3 -5416 5006.0
HSPB1 -4869 5277.5
ATP1B4 -5072 4958.0
CDKN1A -4927 5092.0
BCAR1 -4922 4966.0
FOSB -4733 5147.0
NAB2 -5323 4419.0
RHOC -4944 4715.0
FOSL1 -4491 5185.0
VCL -4538 5034.0
P2RY6 -4646 4887.0
ARHGAP35 -4960 4536.0
WLS -4973 4487.0
SCD -5600 3966.0
DUSP2 -4253 5104.0
CTTN -4605 4611.0
KIF2A -4390 4818.0
LIMK1 -4857 4174.0
FLRT2 -4342 4562.0
STAT3 -3885 5061.0

Click HERE to show all gene set members

All member genes
human mouse
AAMP 2657 111.0
ABCA1 1045 -4559.0
ABHD12 -778 606.0
ABHD17A -1525 -161.0
ABHD17B 1639 1020.0
ABHD17C -2092 2958.0
ABHD6 -2808 -643.0
ABI1 3792 2553.0
ABI2 -308 5048.0
ABL1 -4533 -3545.0
ABR -5353 931.0
ACTA2 -3819 3676.0
ACTB 940 4977.0
ACTG1 -3075 4986.0
ACTN2 -3104 3454.0
ACTR2 3547 3933.0
ACTR3 1376 5136.0
ACVR1B -1186 -5231.0
ACVR2A 3368 -787.0
ACVR2B -3415 -3382.0
ACVRL1 -2348 4062.0
ADAM10 -1509 -1025.0
ADAM12 652 5067.0
ADAM17 2407 2079.0
ADCY1 -3780 -1927.0
ADCY2 -4820 -3731.0
ADCY3 338 187.0
ADCY5 1967 1780.0
ADCY6 -4515 -4206.0
ADCY7 -2820 2292.0
ADCY9 -4889 -4292.0
ADM -1822 -3261.0
ADRA2A -4661 -1779.0
ADRB2 -1092 -2389.0
AGO1 2453 -2704.0
AGO2 -4001 -1788.0
AGO3 2529 -3975.0
AGO4 -3006 -3323.0
AGRN -4903 -2954.0
AGT -4723 -621.0
AGTR1 1167 -1173.0
AHCTF1 4662 -1792.0
AHCYL1 -3386 988.0
AKAP13 1322 -1803.0
AKR1B10 2786 3860.5
AKT1 -4954 342.0
AKT1S1 271 -141.0
AKT2 -4057 -4450.0
AKT3 1343 -320.0
ALDH1A1 -3063 -3787.0
ALDH1A2 -1560 4840.0
ALDH1A3 -260 4205.0
AMER1 -2488 -4016.0
AMHR2 -2583 -3991.0
AMOT -822 2805.0
AMOTL1 -3676 -2407.0
AMOTL2 -4347 1832.0
ANGPT1 -853 -4174.0
ANXA1 537 4544.0
AP2A1 -3632 -420.0
AP2A2 -1058 5063.0
AP2B1 -1157 2251.0
AP2M1 -2746 3372.0
AP2S1 1777 1981.0
APC 3772 -1232.0
APH1A 204 -174.0
APH1B 3428 -1780.0
APOD -340 -153.0
APOE -1428 -89.0
APP -2792 582.0
AR -4468 -5288.0
ARAF -3318 -4367.0
ARAP1 -4961 724.0
ARAP3 -1492 -4424.0
ARC 4190 4333.0
ARF6 3503 4959.0
ARHGAP1 -972 2995.0
ARHGAP10 -3294 -1475.0
ARHGAP11B -4580 2012.0
ARHGAP12 -3916 -1472.0
ARHGAP17 1457 2033.0
ARHGAP18 4554 -3093.0
ARHGAP19 4720 890.0
ARHGAP20 4540 2577.0
ARHGAP21 2554 1537.0
ARHGAP22 -4747 4023.0
ARHGAP24 -3475 1745.0
ARHGAP26 -14 -30.0
ARHGAP27 2783 2453.0
ARHGAP28 -5091 -210.0
ARHGAP29 4465 -2356.0
ARHGAP31 -1030 -4250.0
ARHGAP32 -1319 4278.0
ARHGAP33 -487 1944.0
ARHGAP35 -4960 4536.0
ARHGAP39 -3062 1767.0
ARHGAP4 -3966 4489.0
ARHGAP42 2893 203.0
ARHGAP44 686 4766.0
ARHGAP5 3942 -5135.0
ARHGAP6 4157 1595.0
ARHGAP9 -2941 2431.0
ARHGDIA -1439 4587.0
ARHGEF1 1054 -804.0
ARHGEF10L -5596 -2999.0
ARHGEF11 -1199 -2184.0
ARHGEF12 2630 3657.0
ARHGEF17 -5387 -2157.0
ARHGEF18 2304 -1811.0
ARHGEF2 -4945 2229.0
ARHGEF25 -2669 -1685.0
ARHGEF26 4815 3035.0
ARHGEF3 -4589 -2305.0
ARHGEF37 -5129 -3281.0
ARHGEF4 -3700 -935.0
ARHGEF40 -5458 928.0
ARHGEF6 2856 3398.0
ARHGEF7 -3605 1792.0
ARHGEF9 -3989 -4049.0
ARL2 -4142 -523.0
ARL4C -1078 3661.0
ARPC1A -120 2648.0
ARPC1B 669 4856.0
ARPC2 1357 4617.0
ARPC3 2873 3762.0
ARPC4 1698 2568.0
ARPC5 2295 4844.0
ARRB1 -3133 -14.0
ARRB2 -1089 4317.0
ASH2L -45 -3813.0
ATF1 3129 3014.0
ATF2 3130 1863.0
ATN1 -4709 3150.0
ATP1B4 -5072 4958.0
ATP2A1 -5479 -4584.0
ATP2A2 -2976 515.0
ATP2A3 -4467 1862.0
ATP6AP1 -342 -1790.0
ATP6V0A1 -3809 1763.0
ATP6V0A2 186 -2715.0
ATP6V0B -3461 664.0
ATP6V0D1 -2256 4236.0
ATP6V0E1 1861 4262.0
ATP6V0E2 -1727 -2952.0
ATP6V1A 1633 729.0
ATP6V1B2 2299 4678.0
ATP6V1C1 3521 5003.0
ATP6V1D 3269 -2868.0
ATP6V1E1 3913 -407.0
ATP6V1F -3562 -2379.0
ATP6V1G2 1570 -473.0
ATP6V1H -57 4488.0
AXIN1 -730 3618.0
AXIN2 2452 1001.0
AXL -4171 3942.0
B4GALT1 -1314 2589.0
B9D2 1676 -553.0
BAD -1537 3476.0
BAG4 4135 2734.0
BAIAP2 -641 5041.0
BAMBI 1836 1587.0
BAX -1846 4438.0
BCAR1 -4922 4966.0
BCL2 -4633 -1108.0
BCL2L1 -5181 3434.0
BCL2L11 -4974 2480.0
BCL9 -531 4538.0
BCL9L -5611 934.0
BCR 4627 2917.0
BDNF 1086 5114.0
BIRC2 3739 -2890.0
BIRC3 -4741 978.0
BMI1 3349 2265.0
BMP2 -4256 828.0
BMPR1A 2250 -4902.0
BMPR1B -2483 4217.0
BMPR2 -1969 -3828.0
BOC -3568 -182.0
BRAF 4103 1387.0
BRAP 4689 3899.0
BRK1 2026 3096.0
BTRC -1187 -2758.0
BUB3 4201 1662.0
C3 4311 1838.0
CAB39 2485 2704.0
CAB39L -2451 1815.0
CALCRL 2945 -4855.0
CALM1 -4464 96.0
CAMK2A -5527 -4430.0
CAMK2B -5497 -4230.0
CAMK2D -2223 4137.0
CAMK2G -2097 -4962.0
CAMKK1 -3959 3239.0
CAMKK2 -4965 1216.0
CARM1 -4331 -4868.0
CASP2 2946 -3849.0
CASP3 423 5016.0
CASP8 -1646 3092.0
CASP9 -3269 -2569.0
CAV1 -646 -652.0
CAV2 -403 -3178.0
CBFB 3786 -4544.0
CBL 1736 183.0
CBX2 2360 -1671.0
CBX4 3208 4863.0
CBX6 -482 912.0
CBX8 -917 -541.0
CBY1 -2069 -4372.0
CCDC88C -5319 -4901.0
CCL2 2620 5111.0
CCNC 4650 3537.0
CCND1 757 529.0
CCND3 786 1371.0
CCNE1 4388 4753.0
CCNK 3139 154.0
CCNT1 4896 -1160.0
CCNT2 4381 -5015.0
CD28 -2910 -5023.0
CD55 220 -323.0
CDC14A 957 -3217.0
CDC14B -1745 -5075.0
CDC37 -1724 -675.0
CDC42 3308 754.0
CDC42EP2 -4230 -2445.0
CDC42EP3 -2886 -568.0
CDC73 2659 -1467.0
CDK1 1580 3263.0
CDK2 849 2686.0
CDK4 703 3417.0
CDK5 -1007 -793.0
CDK8 623 -1722.0
CDK9 -1348 4462.0
CDKN1A -4927 5092.0
CDKN1B -3284 -2450.0
CDKN2B -2827 2812.0
CDON 4423 -1345.0
CENPC 3555 -2660.0
CENPL 3768 2470.0
CENPO 1005 440.0
CENPQ 1344 5001.0
CENPT -2196 3930.0
CFL1 -909 4720.0
CFLAR -5551 -3592.0
CHD1 4889 4730.0
CHD3 -3721 -4142.0
CHD4 -4283 464.0
CHD8 4019 -1841.0
CHN1 -5262 1314.0
CHN2 -4930 1142.0
CHUK 216 955.0
CILP -417 3761.0
CIT -2025 478.0
CKAP5 -3973 -1370.0
CLASP1 -3713 1181.0
CLASP2 2507 -309.0
CLIP1 418 -4689.0
CLIP3 -2233 3191.0
CLTA 1218 1668.0
CLTB -4579 4267.0
CLTC 2268 -2802.0
CMKLR1 193 3586.0
CNKSR1 -2870 3756.0
CNOT6L -2201 -298.0
COL4A1 -4755 696.0
COL4A2 -5035 869.0
COL4A3 -3831 -4888.0
COL4A4 -3022 -3981.0
COL4A5 -4320 -3467.0
COL6A1 -1945 2037.0
COL6A2 -1836 2368.0
COL6A3 -119 2674.0
COL6A6 -2138 -3974.0
CPT1A -357 330.0
CREB1 2179 -4329.0
CREBBP 1506 3139.0
CRK 2145 2262.0
CRKL -91 4314.0
CSK -3610 4738.0
CSNK1E -5045 816.0
CSNK1G2 -1933 -1532.0
CSNK2A1 1796 -1733.0
CSNK2A2 2123 1393.0
CSNK2B 1917 -296.0
CTBP1 -3458 -2615.0
CTBP2 760 -812.0
CTNNA1 -2198 4004.0
CTNNB1 1714 -780.0
CTNNBIP1 -4404 -838.0
CTNND1 949 4751.0
CTSD -4817 -4037.0
CTTN -4605 4611.0
CUL1 -3121 -1536.0
CUL3 2833 -224.0
CUL5 2599 -3195.0
CX3CR1 307 4429.0
CXCL12 -4998 -359.0
CXCL16 -920 2782.0
CXXC5 -5255 -3462.0
CYBA -633 3083.0
CYBB -2550 3579.0
CYFIP2 -3775 -1129.0
CYLD -1990 2392.0
CYP26B1 -756 -2217.0
CYP4V2 -2707 523.0
CYSLTR1 -4110 4015.0
DAAM1 3085 4416.0
DAB2IP -5036 810.0
DACT1 -2004 3416.0
DAGLA -5158 -4484.0
DAGLB 3782 -2382.0
DDX5 4191 -2760.0
DEPDC7 3273 2342.0
DERL2 2481 3828.0
DGKA -2368 -2792.0
DGKB -4489 -1726.0
DGKD -5077 333.0
DGKE 1911 -4364.0
DGKH 3337 4302.0
DGKQ -2188 -2361.0
DGKZ -5581 -4639.0
DHRS3 -611 579.0
DHRS4 -691 -4207.5
DIAPH1 3282 5032.0
DIAPH2 4914 4397.0
DKK2 -348 -1527.0
DLAT -1960 -3824.0
DLC1 4953 323.0
DLD 1187 -4737.0
DLG1 -52 918.0
DLG3 -1567 -2178.0
DLG4 -1594 364.0
DLK1 -2814 -1310.0
DLL1 -3980 -4227.0
DNAJB1 4185 5181.0
DNAL4 -1632 -1342.0
DNM1 -747 1193.0
DNM2 -1149 2166.0
DNM3 4865 -1268.0
DOCK1 -226 -41.0
DOCK7 4461 1673.0
DOK1 -1380 -974.0
DRAP1 -2364 -1060.0
DSN1 2075 534.0
DTX2 1547 1918.0
DTX4 4372 -2645.0
DUSP1 -219 4494.0
DUSP10 -5329 2114.0
DUSP16 3082 2356.0
DUSP2 -4253 5104.0
DUSP3 -5149 -5173.0
DUSP4 -3613 3013.0
DUSP5 4084 5213.0
DUSP6 -528 -1256.0
DUSP7 -3477 -3537.0
DUSP8 1715 4654.0
DVL1 -5428 -3357.0
DVL2 -2215 -2076.0
DVL3 -4897 87.0
DYNC1H1 -1442 -2348.0
DYNC1I2 2591 -2971.0
DYNC1LI1 2883 1316.0
DYNC1LI2 1750 -1620.0
DYNC2H1 4934 -2681.0
DYNLL1 -1331 4245.0
DZIP1 -2494 -544.0
E2F1 -529 4663.0
E2F3 -4683 -1694.0
E2F4 -439 5017.0
E2F5 -249 2797.0
EBAG9 2473 -2321.0
ECE1 -1256 -421.0
ECE2 -294 1157.0
EDNRA 1038 -1259.0
EDNRB 1473 1107.0
EED 3304 3671.0
EEF2K -5526 -5159.0
EEPD1 -3576 -4380.0
EGF -4568 -5354.0
EGFR 424 1475.0
EGR1 4164 5238.0
EGR2 -3746 5076.0
EGR3 -3215 5096.0
EIF4B 993 -4215.0
EIF4E 2892 3735.0
EIF4EBP1 -1049 -155.0
EIF4G1 -2988 -4223.0
ELK1 -3862 -42.0
ELMO1 -2166 1449.0
ELMO2 -354 416.0
EP300 3403 -1622.0
EPAS1 21 -3171.0
EPN1 -3102 -3263.0
EPS15 5 -4281.0
EPS15L1 -444 -2403.0
ERBB2 -5511 673.0
ERBB3 -5290 -2790.0
ERLEC1 2742 -3168.0
ESR1 -1770 -3364.0
ETV4 -3510 2835.0
EVC -2706 -5076.0
EVC2 1601 -1641.0
EVL -3566 2476.0
EZH2 4698 4740.0
F11R -2302 -673.0
F2R 1667 3544.0
F2RL1 3379 5206.0
F3 -1733 2260.0
FABP5 -338 -519.0
FADD -571 4877.0
FAM13A 4122 47.0
FAM13B 3174 4485.0
FAS -4771 2899.0
FASN -4976 3183.0
FBXW7 -886 -330.0
FER 1666 2123.0
FES 559 4512.0
FGD1 -3972 725.0
FGD3 -3665 2214.0
FGD4 -4717 -5346.0
FGF1 798 5215.0
FGF2 751 -1095.0
FGF7 -5445 2606.0
FGF9 -5320 -3468.0
FGFBP3 3093 849.0
FGFR1 -1499 -3421.0
FGFR3 3759 4128.0
FGFR4 -5312 -3374.0
FGFRL1 218 -2006.0
FKBP4 1305 500.0
FKBP5 750 553.0
FLNA -3248 3245.0
FLRT2 -4342 4562.0
FLRT3 4144 4201.0
FMNL1 -5159 3750.0
FMNL2 -650 1957.0
FMNL3 -1192 1753.0
FN1 35 4022.0
FNTA 1578 -1804.0
FNTB -690 2634.0
FOS 1865 5273.0
FOSB -4733 5147.0
FOSL1 -4491 5185.0
FOXO1 -432 1302.0
FOXO3 -42 -1131.0
FOXO4 -3493 -4492.0
FOXO6 -4157 -4011.0
FRAT2 4361 4985.0
FRK 194 -2049.0
FRS2 4678 761.0
FRS3 1398 1971.0
FST -3089 985.0
FSTL1 1459 3703.0
FSTL3 -3345 3482.0
FURIN -4221 4117.0
FUZ -3170 -3833.0
FYN -2850 3685.0
FZD1 3076 3251.0
FZD10 -4859 559.0
FZD2 2092 3486.0
FZD4 -5151 -4512.0
FZD5 398 4746.0
FZD6 809 -1518.0
FZD7 1006 -4275.0
FZD8 -3582 -1275.0
FZD9 -5079 -2340.0
GAB1 -1853 -2427.0
GAB2 4053 2422.0
GABBR1 -2887 -2658.0
GAS1 -4081 -719.0
GAS8 -3466 -1161.0
GATAD2A -975 4779.0
GATAD2B 304 3259.0
GDI1 1662 1038.0
GDI2 865 4849.0
GDNF -4043 4741.0
GFRA1 -4438 -2997.0
GGA3 580 1836.0
GLI1 825 -889.0
GLI2 -1180 3498.0
GLI3 3731 101.0
GMIP -2689 3738.0
GNA11 -1689 677.0
GNA12 -3059 4669.0
GNA13 -209 4537.0
GNAI1 183 -419.0
GNAI2 800 3632.0
GNAI3 4221 3815.0
GNAL -3374 128.0
GNAQ 4906 2996.0
GNAS -3163 -641.0
GNB1 177 4937.0
GNB2 -3870 3905.0
GNB3 -3272 -1723.0
GNB4 -3491 -3375.0
GNB5 879 160.0
GNG11 4695 -2336.0
GNG12 612 -821.0
GNG2 802 -279.0
GNG5 415 -1583.0
GNG7 -2742 -5085.0
GOLGA7 1185 2077.0
GOPC 4735 -3346.0
GPAM 1132 -5246.0
GPC1 -5269 -2966.0
GPC4 -5170 -3500.0
GPC6 -2385 158.0
GPNMB -4186 -4646.0
GPR161 3105 2588.0
GPR35 -3228 3674.0
GPS2 2002 3298.0
GPSM1 -3915 373.0
GPSM2 -3093 2286.0
GRB10 -1615 561.0
GRB2 -4050 4496.0
GREM2 -2122 -1835.0
GRK4 -1206 753.0
GRK5 -1067 153.0
GRK6 -1110 3160.0
GSK3A 3319 -75.0
GSK3B 897 3200.0
GTF2A1 4730 4588.0
GTF2A2 4648 -1742.0
GTF2F1 4999 4919.0
GTF2F2 4067 5069.0
H2AFX 2356 5062.0
HBEGF 3484 5272.0
HDAC10 -3116 -2283.0
HDAC11 -4482 3956.0
HDAC2 4386 -1101.0
HDAC3 -178 -4320.0
HDAC4 -5061 -4325.0
HDAC5 -4921 2376.0
HDAC6 -4164 3925.0
HDAC7 -3827 -2596.0
HDAC8 209 -3381.0
HDAC9 -3759 2762.0
HEBP1 18 -401.0
HES1 1695 -1766.0
HEY1 4826 451.0
HEYL -2812 2440.0
HGS 2410 4643.0
HHAT 2490 3704.0
HIF1A -1016 5007.0
HNRNPA1 3878 3701.0
HNRNPF 4978 4644.0
HNRNPH1 3339 4865.0
HNRNPM 4022 -3455.0
HRAS -4545 -3997.0
HSP90AA1 3656 5261.0
HSP90AB1 -639 4629.0
HSPB1 -4869 5277.5
HSPG2 -5351 -404.0
HTR7 2315 -1558.0
ICMT -2315 -1731.0
ID1 -1307 3474.0
ID2 3773 3888.0
ID3 -5372 2129.0
ID4 4977 4601.0
IER3 1170 4216.0
IFT122 -4662 -4720.0
IFT140 -3441 -585.0
IFT172 -2711 -4941.0
IFT52 2101 -1391.0
IFT57 2710 1411.0
IFT88 -1477 -2098.0
IGF1R -144 1646.0
IGF2 -4754 -3030.0
IKBKB -4093 578.0
IL17RD -3179 -934.0
IL1RAP 627 3712.0
IL2RG -1943 3730.0
IL33 1864 3608.0
IL6R -5515 3267.0
IL6ST 3055 -2364.0
INCENP 3676 3359.0
INPP5B 2499 2182.0
INSR -2945 -3083.0
INTU 2230 202.0
IQCE -4375 -1850.0
IQGAP1 -415 3217.0
IRAK1 -4351 -480.0
IRAK4 -569 1975.0
IRS1 -5550 -5121.0
IRS2 3384 2684.0
ITCH 4319 -2959.0
ITGA3 -5514 3010.0
ITGAV -819 50.0
ITGB1 956 4614.0
ITGB3 -488 4915.0
ITGB3BP 1048 -2448.0
ITPR1 4903 -2230.0
ITPR2 1242 -3115.0
ITPR3 -3631 -3441.0
ITSN1 524 -4884.0
JAG1 3237 -2093.0
JAG2 -5593 -2334.0
JAK1 -1869 4228.0
JAK2 -2569 -5057.0
JUN 2469 5225.0
JUNB -2593 5221.0
JUND 1410 4874.0
JUP 1723 4368.0
KALRN -5340 228.0
KANK1 -2800 550.0
KAT2A -5053 -1162.0
KAT2B -3340 -5260.0
KAT5 447 3955.0
KBTBD7 1566 3587.0
KCTD6 2748 3456.0
KDM1A 249 4852.0
KDM1B -2581 3999.0
KDM3A 1176 2715.0
KDM4A 3714 751.0
KDM4B -5221 321.0
KDM4C 814 699.0
KHDRBS1 3426 3923.0
KHDRBS3 964 652.0
KIDINS220 3922 -4620.0
KIF18A 3832 4144.0
KIF2A -4390 4818.0
KIF3A 4718 1513.0
KIF5A 4430 731.0
KIF5B 838 1727.0
KIF7 -422 4053.0
KITLG 4898 -4811.0
KLC1 -3922 2366.0
KLC2 -1732 -2589.0
KLC4 -3559 -1292.0
KLHL12 -2571 -1427.0
KMT2D -1176 -1807.0
KPNA2 5007 3593.0
KRAS 3546 4454.0
KREMEN1 -5547 -2837.0
KSR1 -5578 -5013.0
KTN1 1427 -1547.0
LAMA2 -3799 -762.0
LAMA3 -1011 -4379.0
LAMA4 746 -122.0
LAMA5 -5584 -2744.0
LAMB1 -457 -387.0
LAMB2 -4894 -3069.0
LAMB3 -4991 -4622.0
LAMC1 -3224 2526.0
LAMC2 1351 5152.0
LAMC3 -1576 -1556.0
LAMTOR1 -800 -2671.0
LAMTOR2 -1715 -424.0
LAMTOR3 3134 3162.0
LAMTOR4 -2977 2289.0
LAMTOR5 636 -324.0
LATS1 570 1615.0
LATS2 -438 -1638.0
LDLR -3949 4227.0
LEO1 2784 2307.0
LEPR 3431 15.0
LFNG 160 3175.0
LGR4 -2942 4732.0
LIMK1 -4857 4174.0
LIMK2 -5357 -3206.0
LPAR1 -2162 2733.0
LPAR4 -1042 -2979.0
LPAR6 2280 472.0
LRIG1 -5443 1638.0
LRP1 -3652 1764.0
LRP10 -3203 2162.0
LRP12 4543 4290.0
LRP5 -5463 -1746.5
LRP6 -277 -680.0
LRRK2 -2301 -2272.0
LYN 785 3984.0
LYPLA1 1177 -3760.0
MAD1L1 -3382 2990.0
MAD2L1 1101 3554.0
MADD -5238 -1946.0
MAF1 -1720 -4342.0
MAGED1 -3807 4028.0
MAML1 2770 4603.0
MAML2 2681 640.0
MAML3 -2079 -345.0
MAMLD1 -1668 1073.0
MAP2K1 -506 -2643.0
MAP2K2 -3813 -1797.0
MAP2K5 -4711 -2415.0
MAP3K11 -3624 1948.0
MAP3K7 2142 -4056.0
MAPK1 1988 -648.0
MAPK11 -3385 -333.0
MAPK12 -5264 644.0
MAPK14 -1562 -1635.0
MAPK3 -1024 3725.0
MAPK6 -2278 4523.0
MAPK7 -729 3565.0
MAPK8 457 1106.0
MAPKAP1 -405 2624.0
MAPKAPK2 -2489 -645.0
MAPKAPK3 -4795 -3142.0
MAPRE1 3454 4528.0
MARK3 3178 -2043.0
MBD3 -3419 1364.0
MCF2L -5254 -3074.0
MDK -2963 -3821.0
MDM2 3253 3321.0
MECOM -3697 -4480.0
MED1 4772 -2976.0
MEF2A -5175 -4103.0
MEF2C -4610 -2794.0
MEF2D -5348 -1189.0
MEMO1 -1214 1571.0
MEN1 1348 2492.0
MET -3529 2929.0
METAP1 2806 -1196.0
METAP2 0 -2377.0
MGLL -5374 -4338.0
MIB1 1332 -3751.0
MIB2 -4266 698.0
MIS12 2400 4069.0
MKNK1 -2212 -2777.0
MKRN1 2493 2062.0
MKS1 -1382 -1791.0
MLST8 -3485 -2266.0
MMP2 -692 -2003.0
MOB1A 1776 3807.0
MOB1B -1284 -3204.0
MOV10 -4127 1367.0
MRAS -5239 941.0
MTA1 -4102 4542.0
MTA2 3682 946.0
MTA3 -2123 -1614.0
MTMR4 3209 1995.0
MTOR -1191 -1922.0
MXD4 -1008 -2351.0
MYC 3994 4886.0
MYD88 2726 4679.0
MYH10 50 4851.0
MYH14 -3853 -3913.0
MYH9 -1879 4194.0
MYL12B 1563 1984.0
MYL6 -3628 4190.0
MYL9 -4777 11.0
MYLIP -4026 -2114.0
MYLK -3879 -1681.0
MYO7A -4056 1187.0
MYO9A 3168 2100.0
MYO9B -1901 4055.0
NAB1 -3099 2622.0
NAB2 -5323 4419.0
NAPEPLD -3083 3042.0
NBEA -4442 -2690.0
NCAM1 -3954 4132.0
NCBP1 -1736 4182.0
NCBP2 4188 264.0
NCK1 3718 1288.0
NCK2 -953 -2223.0
NCKAP1 3563 3585.0
NCKIPSD -2821 704.0
NCOA1 2628 -1167.0
NCOA2 146 -5050.0
NCOA3 4584 -321.0
NCOR1 2625 -3925.0
NCOR2 -5167 -1521.0
NCSTN -2504 1262.0
NDE1 4322 -2784.0
NDEL1 4631 1071.0
NEDD4 4583 -4838.0
NEDD4L 4279 -2158.0
NEDD8 -2678 535.0
NELFB -1196 2773.0
NET1 -5146 -2278.0
NEURL1B -4776 -656.0
NF1 3095 3333.0
NF2 -1449 -4728.0
NFATC1 -5337 -1304.0
NFKB1 -4233 3315.0
NFKBIA -4263 4096.0
NGFR 1471 -3377.0
NLK 4629 862.0
NLN -3071 2248.0
NMB -1654 -1450.0
NMT1 -1463 3596.0
NMT2 2059 2124.0
NOG -4672 -936.0
NOTCH1 -5460 44.0
NOTCH3 -1225 773.0
NR1H2 2288 3553.0
NR1H3 -3630 -3237.0
NR3C1 985 -4192.0
NR4A1 -5560 -642.0
NRAS 4354 69.0
NRIP1 -2652 341.0
NRP1 -112 -4259.0
NRP2 2152 -2962.0
NSMAF 2025 -4535.0
NTF3 -2996 -3618.0
NTF4 -3432 -2436.0
NUDC 3212 2586.0
NUMB 2961 3421.0
NUP107 3232 2949.0
NUP133 889 -4048.0
NUP160 3998 1035.0
NUP37 -327 192.0
NUP43 4562 2216.0
NUP85 3181 -393.0
NUP98 4235 5066.0
OBSCN -5563 -3988.0
OCRL 2293 2180.0
OFD1 811 -3024.0
OPHN1 616 -5080.0
OPN3 -2839 4662.0
OS9 -1493 687.0
OTUD3 3881 -3249.0
P2RY2 -5283 -4966.0
P2RY6 -4646 4887.0
P4HB -2525 4048.0
PAFAH1B1 -2026 -2663.0
PAG1 -2006 851.0
PAK1 -5419 -4885.0
PAK2 1525 4805.0
PAQR3 396 3865.0
PARD3 367 -2533.0
PARD6A -1713 -2514.0
PARP1 -2423 -2631.0
PBX1 -4735 -3394.0
PCSK5 1905 1434.0
PCSK6 -3791 258.0
PDE10A 2072 2825.0
PDE1A 2411 710.0
PDE3A 315 -2801.0
PDE4A -3306 -5370.0
PDE4B 3915 -3003.0
PDE4C -2010 -4443.0
PDE4D -1433 -3175.0
PDE6D -2753 4470.0
PDE7A -2549 -3385.0
PDE7B -2696 -5338.0
PDE8A -324 4905.0
PDGFA -4328 -4456.0
PDGFB -606 3347.0
PDGFC 1650 3627.0
PDGFD 1552 -2461.0
PDGFRA 2727 -349.0
PDGFRB -2260 1386.0
PDHA1 -2405 -4451.0
PDHB -133 -3995.0
PDHX -126 -3872.0
PDK1 4600 -3234.0
PDK2 -5450 -3535.0
PDK3 4747 4864.0
PDK4 -712 -5238.0
PDPK1 3443 2222.0
PEA15 -1982 1596.0
PEBP1 -3678 -1052.0
PELP1 2605 1120.0
PENK 634 -2161.0
PFN1 467 1712.0
PFN2 -4209 -3534.0
PGF -3714 1270.0
PHB -586 -2116.0
PHC1 456 -1955.0
PHC2 -3719 4976.0
PHC3 3141 -3012.0
PHLPP1 4854 2844.0
PHLPP2 4694 1443.0
PIK3AP1 966 3680.0
PIK3C3 3439 -1648.0
PIK3CA 365 2811.0
PIK3CB 2760 4994.0
PIK3CD -4322 -4161.0
PIK3R1 2896 -3147.0
PIK3R3 3188 577.0
PIK3R4 3839 -3531.0
PIN1 -3515 1213.0
PIP4K2A 4108 4491.0
PIP4K2C 2827 2664.0
PIP5K1A 4918 -551.0
PIP5K1C -1917 390.0
PKN1 -4379 398.0
PKN2 4933 3171.0
PKN3 -3848 450.0
PLA2G4A 603 3705.0
PLAT 1414 3348.0
PLB1 -3857 -205.0
PLCB1 -1580 -1155.0
PLCB3 -3863 -679.0
PLCB4 -4274 -3778.0
PLCG1 -3955 -4939.0
PLEKHG2 -708 3753.0
PLEKHG5 -4706 -2697.0
PLTP -303 1589.0
PLXNB1 -5451 -1100.0
PLXND1 -4476 -3331.0
PMEPA1 -4540 3945.0
PML 3338 3449.0
POFUT1 -2274 -4182.0
POGLUT1 -1951 -233.0
POLR2A 3861 5046.0
POLR2B 4509 -4119.0
POLR2C 4529 -904.0
POLR2D 1669 2692.0
POLR2E -667 1599.0
POLR2G 89 5112.0
POLR2H -3927 3497.0
POLR2I -154 81.0
POLR2K 2480 -1584.0
POLR2L -4314 4110.0
PORCN 647 -2851.0
POU2F1 3019 -3333.0
PPARD -4213 -2337.0
PPARG -1621 -2269.0
PPID 642 -242.0
PPM1A 3438 -2366.0
PPP1CA -4408 701.0
PPP1CB -1374 -4149.0
PPP1CC 4081 399.0
PPP1R12A 4131 2449.0
PPP1R12B -5005 -1873.0
PPP1R15A 1886 5267.0
PPP2CA 4482 3008.0
PPP2CB 2458 4129.0
PPP2R1A -4013 -696.0
PPP2R1B 3028 4619.0
PPP2R5A 4590 4219.0
PPP2R5B -1524 121.0
PPP2R5C -2508 -3684.0
PPP2R5D -3449 -2058.0
PPP2R5E 4644 1539.0
PPP3CA 109 -2737.0
PPP3CB -3435 -5065.0
PPP3CC -3311 -868.0
PPP5C -4582 -1815.0
PRC1 112 3693.0
PRDM4 2865 -417.0
PREX1 188 1669.0
PRICKLE1 827 -1958.0
PRKAA1 3389 2810.0
PRKAA2 -3219 -5163.0
PRKAB1 3436 1814.0
PRKAB2 -2332 -2820.0
PRKACA -4691 -1606.0
PRKACB -2659 -1546.0
PRKAG1 2103 -1806.0
PRKAG2 -3237 -3533.0
PRKAG3 -5537 -5285.0
PRKAR1A -3106 3030.0
PRKAR1B -2442 2761.0
PRKAR2A -2664 -655.0
PRKAR2B 3460 2616.0
PRKCA -2938 -2924.0
PRKCD -4276 3377.0
PRKCE -4307 -3088.0
PRKCI 416 2276.0
PRKCQ -5095 -4882.0
PRKG1 1401 5121.0
PRKX -1471 4883.0
PRR5 -837 422.0
PSAP -2247 -4040.0
PSEN1 2070 2061.0
PSEN2 -5371 -1458.0
PSENEN -2638 482.0
PSMA1 2820 3328.0
PSMA3 3434 -4.0
PSMA4 769 958.0
PSMA6 2199 -1044.0
PSMA7 -2980 976.0
PSMB1 954 2628.0
PSMB10 -1800 2907.0
PSMB2 618 2471.0
PSMB4 -235 2096.0
PSMB5 -4113 -606.0
PSMB6 -793 914.0
PSMB7 -831 -1453.0
PSMB8 -675 2066.0
PSMB9 -1611 -2973.0
PSMC1 449 -336.0
PSMC2 -1311 3241.0
PSMC3 -2439 -369.0
PSMC4 2724 1416.0
PSMC5 1212 -1123.0
PSMC6 -2520 3423.0
PSMD1 2619 -1191.0
PSMD10 -1227 525.0
PSMD11 995 5183.0
PSMD12 3831 536.0
PSMD13 821 1665.0
PSMD14 -635 3816.0
PSMD2 -713 -555.0
PSMD3 -3343 2226.0
PSMD4 -214 2558.0
PSMD5 1807 3558.0
PSMD6 3537 -2207.0
PSMD7 -2329 1233.0
PSMD8 -3171 4626.0
PSMD9 4204 -970.0
PSME1 -2771 3350.0
PSME2 -4085 3584.0
PSME3 3333 3379.0
PSME4 1960 -4574.0
PSMF1 683 -1480.0
PTBP1 3063 4257.0
PTCH1 326 -1956.0
PTCH2 -2962 1145.0
PTEN 2797 2721.0
PTGER4 4219 4674.0
PTGES3 1328 3635.0
PTGIR -370 3143.0
PTH1R -2770 -1748.0
PTHLH -3836 1237.0
PTK2 -2497 -1508.0
PTK2B -2461 3862.0
PTPN1 1531 4585.0
PTPN11 -1575 -666.0
PTPN12 4141 5021.0
PTPN18 -4024 2425.0
PTPN2 4314 4306.0
PTPN3 2224 -5244.0
PTPN6 -931 4799.0
PTPRA -402 3653.0
PTPRJ 391 3748.0
PTPRK 211 3408.0
PTPRO 1419 3577.0
PTPRS -4613 -4187.0
PXN -4750 204.0
PYGO1 -1566 -4992.0
PYGO2 -2448 4296.0
RAB4A 1790 -2437.0
RAC1 2525 1457.0
RAC2 41 4946.0
RACGAP1 4239 3684.0
RAD21 4417 4508.0
RAF1 1712 -1646.0
RALA -1368 504.0
RALB -2362 2338.0
RALBP1 2524 1010.0
RALGDS -5190 -623.0
RAMP1 -5448 209.0
RANBP10 -4779 2768.0
RANBP2 4470 -3848.0
RANBP9 4005 219.0
RANGAP1 483 4340.0
RAP1A -689 3710.0
RAP1B 4479 4565.0
RAPGEF1 -3992 3326.0
RAPGEF2 4504 -3856.0
RAPGEF3 108 -2918.0
RAPGEF4 4622 3189.0
RARA -5250 2741.0
RARB -2995 -2000.0
RARG -4431 -4039.0
RASA1 -612 -183.0
RASA2 3565 62.0
RASA3 -4990 -756.0
RASAL2 3510 -2420.0
RASGRF2 4373 -3165.0
RASGRP2 -2556 -4280.0
RASGRP3 -4774 -5308.0
RBBP4 1072 2469.0
RBBP5 4628 41.0
RBBP7 -924 -2291.0
RBCK1 -4445 -4297.0
RBFOX2 -4887 -4736.0
RBL1 -1617 778.0
RBP1 2113 1028.0
RBPJ 305 4930.0
RBX1 -733 -968.0
RCC2 4178 3436.0
RCE1 2361 3617.0
RCOR1 4776 -5.0
RDH10 1095 4208.0
RDH11 2085 5094.0
RDH13 -3663 -2400.0
RDH14 4051 -4589.0
RDH5 -3933 1325.0
REEP1 -5059 -5072.0
REEP2 -2968 -88.0
REEP3 2053 2981.0
REEP4 1148 2887.0
REEP5 -3723 -2302.0
REEP6 -1143 -275.0
RELA 1783 4531.0
REST 1113 2305.0
RETSAT 2667 -5363.0
RFNG -4947 668.0
RGL1 -161 307.0
RGL2 -4344 -3999.0
RGS10 -785 2155.0
RGS12 -4393 871.0
RGS14 -5528 3524.0
RGS16 -723 4710.0
RGS19 -2099 3011.0
RGS2 -581 4832.0
RGS3 -5494 407.0
RGS4 1724 5056.0
RGS5 2155 -3329.0
RGS9BP -2609 3101.0
RHEB 172 2951.0
RHOA 539 4193.0
RHOB 4609 5128.0
RHOBTB1 4915 -4473.0
RHOBTB2 -3428 -5200.0
RHOC -4944 4715.0
RHOG -1207 4926.0
RHOJ 164 592.0
RHOQ -1357 -5005.0
RHOT1 -3626 -4062.0
RHOT2 -5266 -3183.0
RHOU -4229 -325.0
RHPN2 3217 -455.0
RICTOR 3562 -2934.0
RING1 -1968 -125.0
RIPK1 325 719.0
RIPK2 3609 4837.0
RIT1 4448 3432.0
RNF111 3964 4756.0
RNF146 -3773 -518.0
RNF2 3038 4651.0
RNF31 -839 477.0
RNF41 1588 4940.0
ROCK1 4876 -54.0
ROCK2 2205 314.0
ROR1 -187 -2078.0
ROR2 428 2605.0
RPGRIP1L 1195 1347.0
RPS27A 783 1840.0
RPS6 -245 3549.0
RPS6KA1 -1481 -46.0
RPS6KA2 -4748 -5153.0
RPS6KA3 952 410.0
RPS6KA5 51 -5295.0
RPS6KB1 2776 -2119.0
RPS6KB2 -4132 2252.0
RPTOR -4596 2076.0
RRAD 4389 4605.0
RRAGA 2383 4477.0
RRAGB -366 -548.0
RRAGC 2091 945.0
RRAGD -4673 -5179.0
RTKN -5092 -1645.0
RTN4 -2844 -3699.0
RUNX1 -2434 4962.0
RUVBL1 -1240 372.0
RXRA -5519 -4191.0
RXRB -1250 -3372.0
RXRG -4055 1680.0
RYK 1626 948.0
S1PR1 2689 1552.0
S1PR2 520 3527.0
S1PR3 2047 -1630.0
SAV1 3362 -1718.0
SCAI -726 -2421.0
SCD -5600 3966.0
SCMH1 -5007 -1597.0
SCRIB -5277 1352.0
SCUBE2 -3745 909.0
SDC1 -2046 212.0
SDC2 1756 4483.0
SDC3 -4619 2809.0
SDC4 -2393 5153.0
SEC13 730 1702.0
SEH1L 1085 4263.0
SEL1L 3241 -1874.0
SERPINE1 -211 5168.0
SFPQ 4544 3976.0
SFRP1 2147 1134.0
SFRP2 -1497 -1838.0
SGK1 1084 -5256.0
SH2B1 -3841 -971.0
SH2B2 -4553 4224.0
SH2B3 -4833 2922.0
SH3GL1 -2937 2592.0
SH3KBP1 1014 -3709.0
SHARPIN -3397 -3280.0
SHC1 3976 3605.0
SHC2 -3710 1658.0
SHOC2 4514 2152.0
SIRT6 1524 3425.0
SKA2 2399 907.0
SKI -3187 1297.0
SKIL 1818 1156.0
SKP1 2028 -2504.0
SLC38A9 969 -2953.0
SMAD1 -2920 5081.0
SMAD2 1125 4898.0
SMAD3 -3794 -5343.0
SMAD4 2354 -52.0
SMAD5 3745 3836.0
SMAD6 2009 -2772.0
SMAD7 -1051 1964.0
SMAD9 517 -1158.0
SMARCA4 -3874 -1402.0
SMC1A 3824 -810.0
SMC3 4878 2878.0
SMO -4360 208.0
SMPD2 -1826 -3571.0
SMURF1 4443 2060.0
SMURF2 1070 4724.0
SNAI1 4055 3954.0
SNAI2 -1085 145.0
SNW1 3618 4819.0
SNX3 289 3939.0
SOCS1 199 4033.0
SOCS3 -283 5103.0
SOCS6 -2366 85.0
SOS1 -1962 -1007.0
SOS2 -563 -3782.0
SOX13 -4049 -1656.0
SOX4 -977 2705.0
SOX6 -1218 -5107.0
SOX9 2175 5159.0
SP1 1787 -1016.0
SPARC -2672 -571.0
SPHK1 443 3714.0
SPOP -4970 -4551.0
SPOPL 913 -5143.0
SPP1 1162 3043.0
SPPL2A 1672 -4879.0
SPRED1 3312 3519.0
SPRED2 1200 -423.0
SPRED3 -2447 -1440.0
SPRY1 4004 -2656.0
SPRY2 -3817 1795.0
SPTAN1 -2425 -1976.0
SPTB -5499 -3499.0
SPTBN1 -2919 -3387.0
SQSTM1 -3803 3545.0
SRC -3910 1378.0
SREBF1 -5230 594.0
SRF -4281 3323.0
SRGAP1 938 747.0
SRGAP3 -3043 -1274.0
ST3GAL3 -4844 -2274.0
ST3GAL4 -2946 3771.0
ST3GAL6 -2222 -2692.0
STAG1 4246 -1940.0
STAG2 31 -4179.0
STAM 3932 2747.0
STAM2 3489 2601.0
STAP2 -2832 -2946.0
STARD13 -4235 4202.0
STARD8 -2599 501.0
STAT1 236 -1738.0
STAT3 -3885 5061.0
STAT5A -4125 -4573.0
STAT5B -5022 -5306.0
STAT6 -5317 -1263.0
STK11 -4884 -2152.0
STK3 4986 2659.0
STK4 3116 2333.0
STMN1 -959 4388.0
STRADA -1805 -1768.0
STRADB 741 -3450.0
STRAP 3710 -49.0
STRN -104 2814.0
STUB1 -2898 -690.0
SUFU -1035 1011.0
SUZ12 3871 1927.0
SYDE1 -968 2028.0
SYDE2 -263 -616.0
SYNGAP1 -3658 1029.0
SYVN1 -192 4796.0
TAB1 -4874 -4753.0
TAB2 2791 681.0
TAB3 2116 4834.0
TACC3 -1415 4377.0
TAOK1 1644 -3805.0
TAS1R1 -4010 -4009.0
TAX1BP1 3222 -1141.0
TAX1BP3 -710 4499.0
TBL1XR1 1876 -2165.0
TBP 1137 2611.0
TCF12 1614 4124.0
TCF4 3907 -3970.0
TCF7 1204 2448.0
TCF7L1 -3205 2935.0
TCF7L2 -74 -1755.0
TCIRG1 -3600 4552.0
TEC 3728 2609.0
TEK 3580 -2188.0
TFDP1 -2245 -2659.0
TFDP2 4029 -5361.0
TGFB1 -3111 4943.0
TGFBR1 -2914 981.0
TGFBR2 -927 1736.0
TGIF1 -2131 3663.0
THBS1 762 4431.0
THBS2 379 -717.0
THBS3 -4348 2300.0
THBS4 -280 1229.0
THEM4 -3616 -500.0
TIA1 3336 -4747.0
TIAL1 1738 -1565.0
TIAM1 2024 403.0
TIAM2 -3379 5163.0
TJP1 405 -3133.0
TJP2 784 4801.0
TLE1 3589 1592.0
TLE2 -3403 -1227.0
TLE3 -5298 1309.0
TLE4 3498 4283.0
TLN1 -3918 2975.0
TMED2 2813 -2139.0
TMED5 4129 520.0
TNFAIP3 -5203 1811.0
TNFRSF10A -3936 1259.5
TNFRSF10B -1612 1259.5
TNFRSF10D -3227 1259.5
TNFRSF1A -4666 3362.0
TNKS 2621 2015.0
TNKS2 4726 -3651.0
TNRC6A 3585 -573.0
TNRC6B 3118 -4527.0
TNRC6C -2020 -1918.0
TNS3 -5416 5006.0
TP53 575 3751.0
TPH1 -823 -4373.0
TRADD -706 -1473.0
TRAF1 -969 -15.0
TRAF2 -1546 980.0
TRAF6 3468 1207.0
TRIB1 -2384 4717.0
TRIB3 -1004 3791.0
TRIM27 4120 4461.0
TRIM33 2796 2074.0
TRIO 1163 -2925.0
TRIP10 -4547 -4340.0
TRRAP 4073 -1631.0
TSC1 2577 -2625.0
TSC2 -4999 -1090.0
TTC21B 2366 1541.0
TULP3 -2192 473.0
TYK2 -3123 -50.0
UBC 2672 4480.0
UBE2D1 -1588 -4032.0
UBE2D3 1424 4934.0
UBE2M 1247 1561.0
UCHL5 1313 -1233.0
UHMK1 4180 -4404.0
ULK3 -5363 610.0
USF1 3062 -604.0
USF2 -3406 -2859.0
USP13 -3948 -2937.0
USP15 4197 -5011.0
USP2 -5039 -2958.0
USP21 -1420 1133.0
USP34 3176 -3903.0
USP4 276 414.0
USP7 3857 277.0
USP8 4301 -3517.0
USP9X 1458 -4487.0
UTS2R -5043 -994.0
VANGL2 -5207 -1833.0
VAPA 2838 2906.0
VAV2 -4959 -899.0
VAV3 187 -1063.0
VCL -4538 5034.0
VEGFA -4571 -5196.0
VEGFB -4617 -136.0
VEGFC 1169 1473.0
VPS26A 3259 2594.0
VPS29 -241 2900.0
VPS35 2429 -4568.0
VRK3 464 -1371.0
VWF -779 -106.0
WASF2 -4656 1511.0
WASF3 -1015 718.0
WASL 2683 3268.0
WDR19 1384 3644.0
WDR35 2475 -4711.0
WDR83 1010 -3888.0
WIPF1 -2552 1682.0
WIPF2 3299 -502.0
WIPF3 -5107 -5055.0
WLS -4973 4487.0
WNT11 -5040 -2882.0
WNT4 -5296 -3164.0
WNT5A 1837 -2457.0
WNT5B -2395 1478.0
WNT9A -4855 -2220.0
WWOX 1055 -3182.0
WWP1 -1200 -5241.0
WWP2 -1852 3478.0
WWTR1 -2503 809.0
XK -5173 2038.0
XPO1 990 1809.0
YAP1 -476 3863.0
YBX1 -681 1282.0
YES1 -176 -2941.0
YWHAB 3680 3415.0
YWHAE 1394 -914.0
YWHAG -2372 -3104.0
YWHAH -2777 4700.0
YWHAQ 963 3739.0
YWHAZ 2019 4495.0
ZDHHC21 331 309.0
ZDHHC7 671 905.0
ZDHHC9 -3396 1619.0
ZFYVE16 -2702 -1297.0
ZFYVE9 -3150 -4894.0
ZNF217 4998 4301.0
ZNRF3 -803 3843.0
ZRANB1 2309 2414.0
ZW10 1474 1263.0
ZWINT 2778 5161.0



HIV Life Cycle

HIV Life Cycle
metric value
setSize 122
pMANOVA 2.92e-14
p.adjustMANOVA 2.12e-12
s.dist 0.447
s.human 0.349
s.mouse 0.279
p.human 2.98e-11
p.mouse 1.14e-07




Top 20 genes
Gene human mouse
TAF4B 4967 5209
GTF2F1 4999 4919
TAF7 4717 4909
GTF2B 4276 5124
GTF2A1 4730 4588
NUP98 4235 5066
GTF2F2 4067 5069
POLR2A 3861 5046
TAF3 4294 4474
NUP54 4508 3831
SUPT16H 3885 4363
NUP205 4438 3588
TAF2 4591 3381
FEN1 4094 3551
TAF5 4309 2830
UBC 2672 4480
RAE1 4471 2389
NUP43 4562 2216
TAF12 3100 3164
PSIP1 3390 2882

Click HERE to show all gene set members

All member genes
human mouse
AAAS -3476 1550.0
BANF1 -2281 674.0
CCNH 3825 -1657.0
CCNK 3139 154.0
CCNT1 4896 -1160.0
CCNT2 4381 -5015.0
CDK7 1571 -2032.0
CDK9 -1348 4462.0
CHMP2A 1155 2310.0
CHMP2B 967 -4167.0
CHMP3 -3919 1578.0
CHMP4B -1125 329.0
CHMP5 3372 -357.0
CHMP6 -4368 279.0
CHMP7 1743 -3701.0
CTDP1 2071 4335.0
ELL -3990 3019.0
ERCC2 824 2393.0
ERCC3 473 1570.0
FEN1 4094 3551.0
FURIN -4221 4117.0
GTF2A1 4730 4588.0
GTF2A2 4648 -1742.0
GTF2B 4276 5124.0
GTF2E1 2188 1803.0
GTF2E2 2041 120.0
GTF2F1 4999 4919.0
GTF2F2 4067 5069.0
GTF2H1 3886 1058.0
GTF2H2 4419 -2446.5
GTF2H3 -1925 467.0
GTF2H5 -878 -1711.0
HMGA1 598 5099.0
KPNA1 1833 3439.0
LIG1 -3127 3257.0
LIG4 2394 -3296.0
MNAT1 830 -2433.0
MVB12A -2807 711.0
MVB12B -5576 -5074.0
NCBP1 -1736 4182.0
NCBP2 4188 264.0
NDC1 1273 -2350.0
NEDD4L 4279 -2158.0
NELFA 356 3929.0
NELFB -1196 2773.0
NELFCD 1896 -2294.0
NELFE -2178 3334.0
NMT1 -1463 3596.0
NMT2 2059 2124.0
NUP107 3232 2949.0
NUP133 889 -4048.0
NUP153 4762 1533.0
NUP155 4306 -2233.0
NUP160 3998 1035.0
NUP188 2117 3830.0
NUP205 4438 3588.0
NUP214 3124 665.0
NUP35 4571 649.0
NUP37 -327 192.0
NUP43 4562 2216.0
NUP54 4508 3831.0
NUP85 3181 -393.0
NUP88 1244 2212.0
NUP93 -1503 3903.0
NUP98 4235 5066.0
PDCD6IP 1350 4607.0
POLR2A 3861 5046.0
POLR2B 4509 -4119.0
POLR2C 4529 -904.0
POLR2D 1669 2692.0
POLR2E -667 1599.0
POLR2G 89 5112.0
POLR2H -3927 3497.0
POLR2I -154 81.0
POLR2K 2480 -1584.0
POLR2L -4314 4110.0
PPIA -4031 4697.0
PSIP1 3390 2882.0
RAE1 4471 2389.0
RAN 2329 1938.0
RANBP1 745 4765.0
RANBP2 4470 -3848.0
RANGAP1 483 4340.0
RCC1 997 3619.0
RNGTT 4414 1057.0
RNMT 4864 -807.0
RPS27A 783 1840.0
SEC13 730 1702.0
SEH1L 1085 4263.0
SSRP1 1755 3948.0
SUPT16H 3885 4363.0
SUPT4H1 3648 -1203.0
SUPT5H 1321 3508.0
TAF1 1708 -350.0
TAF10 -273 2957.0
TAF11 2962 -484.0
TAF12 3100 3164.0
TAF13 4749 1567.0
TAF2 4591 3381.0
TAF3 4294 4474.0
TAF4 -1340 3063.0
TAF4B 4967 5209.0
TAF5 4309 2830.0
TAF6 -912 55.0
TAF7 4717 4909.0
TAF9B 1874 519.0
TBP 1137 2611.0
TCEA1 4037 647.0
TPR 2984 -1026.0
TSG101 260 2655.0
UBAP1 -1913 4784.0
UBC 2672 4480.0
VPS37A 1868 -4488.0
VPS37B -3496 2909.0
VPS37C 1403 3419.0
VPS4A -1545 -2086.0
VPS4B 4523 1960.0
VTA1 3283 447.0
XPO1 990 1809.0
XRCC4 -4731 -1301.0
XRCC5 4010 -2853.0
XRCC6 3225 -1241.0



HIV Infection

HIV Infection
metric value
setSize 187
pMANOVA 5e-14
p.adjustMANOVA 3.43e-12
s.dist 0.36
s.human 0.243
s.mouse 0.265
p.human 1.09e-08
p.mouse 4.99e-10




Top 20 genes
Gene human mouse
TAF4B 4967 5209
GTF2F1 4999 4919
TAF7 4717 4909
GTF2B 4276 5124
GTF2A1 4730 4588
NUP98 4235 5066
GTF2F2 4067 5069
POLR2A 3861 5046
TAF3 4294 4474
NUP54 4508 3831
SUPT16H 3885 4363
SLC25A5 3467 4820
NUP205 4438 3588
TAF2 4591 3381
FEN1 4094 3551
KPNB1 3619 3517
TAF5 4309 2830
UBC 2672 4480
PSME3 3333 3379
RAE1 4471 2389

Click HERE to show all gene set members

All member genes
human mouse
AAAS -3476 1550.0
AP1B1 -4552 -34.0
AP1G1 4140 2569.0
AP1M1 3732 1437.0
AP1S1 -1410 812.0
AP1S2 -1634 1536.0
AP2A1 -3632 -420.0
AP2A2 -1058 5063.0
AP2B1 -1157 2251.0
AP2M1 -2746 3372.0
AP2S1 1777 1981.0
ARF1 566 4500.0
ATP6V1H -57 4488.0
B2M -731 1593.0
BANF1 -2281 674.0
BTRC -1187 -2758.0
CCNH 3825 -1657.0
CCNK 3139 154.0
CCNT1 4896 -1160.0
CCNT2 4381 -5015.0
CD28 -2910 -5023.0
CDK7 1571 -2032.0
CDK9 -1348 4462.0
CHMP2A 1155 2310.0
CHMP2B 967 -4167.0
CHMP3 -3919 1578.0
CHMP4B -1125 329.0
CHMP5 3372 -357.0
CHMP6 -4368 279.0
CHMP7 1743 -3701.0
CTDP1 2071 4335.0
CUL5 2599 -3195.0
ELL -3990 3019.0
ELMO1 -2166 1449.0
ERCC2 824 2393.0
ERCC3 473 1570.0
FEN1 4094 3551.0
FURIN -4221 4117.0
FYN -2850 3685.0
GTF2A1 4730 4588.0
GTF2A2 4648 -1742.0
GTF2B 4276 5124.0
GTF2E1 2188 1803.0
GTF2E2 2041 120.0
GTF2F1 4999 4919.0
GTF2F2 4067 5069.0
GTF2H1 3886 1058.0
GTF2H2 4419 -2446.5
GTF2H3 -1925 467.0
GTF2H5 -878 -1711.0
HMGA1 598 5099.0
KPNA1 1833 3439.0
KPNB1 3619 3517.0
LIG1 -3127 3257.0
LIG4 2394 -3296.0
MNAT1 830 -2433.0
MVB12A -2807 711.0
MVB12B -5576 -5074.0
NCBP1 -1736 4182.0
NCBP2 4188 264.0
NDC1 1273 -2350.0
NEDD4L 4279 -2158.0
NELFA 356 3929.0
NELFB -1196 2773.0
NELFCD 1896 -2294.0
NELFE -2178 3334.0
NMT1 -1463 3596.0
NMT2 2059 2124.0
NUP107 3232 2949.0
NUP133 889 -4048.0
NUP153 4762 1533.0
NUP155 4306 -2233.0
NUP160 3998 1035.0
NUP188 2117 3830.0
NUP205 4438 3588.0
NUP214 3124 665.0
NUP35 4571 649.0
NUP37 -327 192.0
NUP43 4562 2216.0
NUP54 4508 3831.0
NUP85 3181 -393.0
NUP88 1244 2212.0
NUP93 -1503 3903.0
NUP98 4235 5066.0
PACS1 -4826 1664.0
PAK2 1525 4805.0
PDCD6IP 1350 4607.0
POLR2A 3861 5046.0
POLR2B 4509 -4119.0
POLR2C 4529 -904.0
POLR2D 1669 2692.0
POLR2E -667 1599.0
POLR2G 89 5112.0
POLR2H -3927 3497.0
POLR2I -154 81.0
POLR2K 2480 -1584.0
POLR2L -4314 4110.0
PPIA -4031 4697.0
PSIP1 3390 2882.0
PSMA1 2820 3328.0
PSMA3 3434 -4.0
PSMA4 769 958.0
PSMA6 2199 -1044.0
PSMA7 -2980 976.0
PSMB1 954 2628.0
PSMB10 -1800 2907.0
PSMB2 618 2471.0
PSMB4 -235 2096.0
PSMB5 -4113 -606.0
PSMB6 -793 914.0
PSMB7 -831 -1453.0
PSMB8 -675 2066.0
PSMB9 -1611 -2973.0
PSMC1 449 -336.0
PSMC2 -1311 3241.0
PSMC3 -2439 -369.0
PSMC4 2724 1416.0
PSMC5 1212 -1123.0
PSMC6 -2520 3423.0
PSMD1 2619 -1191.0
PSMD10 -1227 525.0
PSMD11 995 5183.0
PSMD12 3831 536.0
PSMD13 821 1665.0
PSMD14 -635 3816.0
PSMD2 -713 -555.0
PSMD3 -3343 2226.0
PSMD4 -214 2558.0
PSMD5 1807 3558.0
PSMD6 3537 -2207.0
PSMD7 -2329 1233.0
PSMD8 -3171 4626.0
PSMD9 4204 -970.0
PSME1 -2771 3350.0
PSME2 -4085 3584.0
PSME3 3333 3379.0
PSME4 1960 -4574.0
PSMF1 683 -1480.0
RAC1 2525 1457.0
RAE1 4471 2389.0
RAN 2329 1938.0
RANBP1 745 4765.0
RANBP2 4470 -3848.0
RANGAP1 483 4340.0
RBX1 -733 -968.0
RCC1 997 3619.0
RNGTT 4414 1057.0
RNMT 4864 -807.0
RPS27A 783 1840.0
SEC13 730 1702.0
SEH1L 1085 4263.0
SKP1 2028 -2504.0
SLC25A4 -1327 -2889.0
SLC25A5 3467 4820.0
SSRP1 1755 3948.0
SUPT16H 3885 4363.0
SUPT4H1 3648 -1203.0
SUPT5H 1321 3508.0
TAF1 1708 -350.0
TAF10 -273 2957.0
TAF11 2962 -484.0
TAF12 3100 3164.0
TAF13 4749 1567.0
TAF2 4591 3381.0
TAF3 4294 4474.0
TAF4 -1340 3063.0
TAF4B 4967 5209.0
TAF5 4309 2830.0
TAF6 -912 55.0
TAF7 4717 4909.0
TAF9B 1874 519.0
TBP 1137 2611.0
TCEA1 4037 647.0
TPR 2984 -1026.0
TSG101 260 2655.0
UBAP1 -1913 4784.0
UBC 2672 4480.0
VPS37A 1868 -4488.0
VPS37B -3496 2909.0
VPS37C 1403 3419.0
VPS4A -1545 -2086.0
VPS4B 4523 1960.0
VTA1 3283 447.0
XPO1 990 1809.0
XRCC4 -4731 -1301.0
XRCC5 4010 -2853.0
XRCC6 3225 -1241.0



Late Phase of HIV Life Cycle

Late Phase of HIV Life Cycle
metric value
setSize 112
pMANOVA 8.01e-14
p.adjustMANOVA 5.2e-12
s.dist 0.458
s.human 0.359
s.mouse 0.285
p.human 5.75e-11
p.mouse 1.98e-07




Top 20 genes
Gene human mouse
TAF4B 4967 5209
GTF2F1 4999 4919
TAF7 4717 4909
GTF2B 4276 5124
GTF2A1 4730 4588
NUP98 4235 5066
GTF2F2 4067 5069
POLR2A 3861 5046
TAF3 4294 4474
NUP54 4508 3831
SUPT16H 3885 4363
NUP205 4438 3588
TAF2 4591 3381
TAF5 4309 2830
UBC 2672 4480
RAE1 4471 2389
NUP43 4562 2216
TAF12 3100 3164
NUP107 3232 2949
CTDP1 2071 4335

Click HERE to show all gene set members

All member genes
human mouse
AAAS -3476 1550.0
CCNH 3825 -1657.0
CCNK 3139 154.0
CCNT1 4896 -1160.0
CCNT2 4381 -5015.0
CDK7 1571 -2032.0
CDK9 -1348 4462.0
CHMP2A 1155 2310.0
CHMP2B 967 -4167.0
CHMP3 -3919 1578.0
CHMP4B -1125 329.0
CHMP5 3372 -357.0
CHMP6 -4368 279.0
CHMP7 1743 -3701.0
CTDP1 2071 4335.0
ELL -3990 3019.0
ERCC2 824 2393.0
ERCC3 473 1570.0
FURIN -4221 4117.0
GTF2A1 4730 4588.0
GTF2A2 4648 -1742.0
GTF2B 4276 5124.0
GTF2E1 2188 1803.0
GTF2E2 2041 120.0
GTF2F1 4999 4919.0
GTF2F2 4067 5069.0
GTF2H1 3886 1058.0
GTF2H2 4419 -2446.5
GTF2H3 -1925 467.0
GTF2H5 -878 -1711.0
MNAT1 830 -2433.0
MVB12A -2807 711.0
MVB12B -5576 -5074.0
NCBP1 -1736 4182.0
NCBP2 4188 264.0
NDC1 1273 -2350.0
NEDD4L 4279 -2158.0
NELFA 356 3929.0
NELFB -1196 2773.0
NELFCD 1896 -2294.0
NELFE -2178 3334.0
NMT1 -1463 3596.0
NMT2 2059 2124.0
NUP107 3232 2949.0
NUP133 889 -4048.0
NUP153 4762 1533.0
NUP155 4306 -2233.0
NUP160 3998 1035.0
NUP188 2117 3830.0
NUP205 4438 3588.0
NUP214 3124 665.0
NUP35 4571 649.0
NUP37 -327 192.0
NUP43 4562 2216.0
NUP54 4508 3831.0
NUP85 3181 -393.0
NUP88 1244 2212.0
NUP93 -1503 3903.0
NUP98 4235 5066.0
PDCD6IP 1350 4607.0
POLR2A 3861 5046.0
POLR2B 4509 -4119.0
POLR2C 4529 -904.0
POLR2D 1669 2692.0
POLR2E -667 1599.0
POLR2G 89 5112.0
POLR2H -3927 3497.0
POLR2I -154 81.0
POLR2K 2480 -1584.0
POLR2L -4314 4110.0
PPIA -4031 4697.0
RAE1 4471 2389.0
RAN 2329 1938.0
RANBP1 745 4765.0
RANBP2 4470 -3848.0
RANGAP1 483 4340.0
RCC1 997 3619.0
RNGTT 4414 1057.0
RNMT 4864 -807.0
RPS27A 783 1840.0
SEC13 730 1702.0
SEH1L 1085 4263.0
SSRP1 1755 3948.0
SUPT16H 3885 4363.0
SUPT4H1 3648 -1203.0
SUPT5H 1321 3508.0
TAF1 1708 -350.0
TAF10 -273 2957.0
TAF11 2962 -484.0
TAF12 3100 3164.0
TAF13 4749 1567.0
TAF2 4591 3381.0
TAF3 4294 4474.0
TAF4 -1340 3063.0
TAF4B 4967 5209.0
TAF5 4309 2830.0
TAF6 -912 55.0
TAF7 4717 4909.0
TAF9B 1874 519.0
TBP 1137 2611.0
TCEA1 4037 647.0
TPR 2984 -1026.0
TSG101 260 2655.0
UBAP1 -1913 4784.0
UBC 2672 4480.0
VPS37A 1868 -4488.0
VPS37B -3496 2909.0
VPS37C 1403 3419.0
VPS4A -1545 -2086.0
VPS4B 4523 1960.0
VTA1 3283 447.0
XPO1 990 1809.0



Nervous system development

Nervous system development
metric value
setSize 395
pMANOVA 3.49e-13
p.adjustMANOVA 2.15e-11
s.dist 0.205
s.human -0.117
s.mouse 0.169
p.human 7.65e-05
p.mouse 1.19e-08




Top 20 genes
Gene human mouse
ITGA5 -4752 5178
NAB2 -5323 4419
RHOC -4944 4715
ARHGAP35 -4960 4536
ST8SIA2 -5423 3963
SREBF2 -4703 4517
LIMK1 -4857 4174
PLXNA2 -5392 3724
CLTB -4579 4267
GDNF -4043 4741
EGR2 -3746 5076
SCN5A -5309 3520
MSN -3907 4668
GRB2 -4050 4496
GIT1 -4208 4025
NCAM1 -3954 4132
ITGA9 -5247 3076
PLXNA3 -5112 3055
ACTG1 -3075 4986
MYL6 -3628 4190

Click HERE to show all gene set members

All member genes
human mouse
ABL1 -4533 -3545
ABL2 4315 4927
ABLIM1 -4649 2025
ABLIM2 -5452 -4200
ABLIM3 -5094 -4780
ACTB 940 4977
ACTG1 -3075 4986
ACTR2 3547 3933
ACTR3 1376 5136
ADAM10 -1509 -1025
AGAP2 -3629 2373
AGRN -4903 -2954
ALCAM 3531 4633
ANK1 -5583 -3806
ANK2 -4297 -4989
ANK3 1331 -4389
AP2A1 -3632 -420
AP2A2 -1058 5063
AP2B1 -1157 2251
AP2M1 -2746 3372
AP2S1 1777 1981
APH1A 204 -174
APH1B 3428 -1780
ARHGAP35 -4960 4536
ARHGAP39 -3062 1767
ARHGEF11 -1199 -2184
ARHGEF12 2630 3657
ARHGEF28 -2642 -552
ARHGEF7 -3605 1792
ARPC1A -120 2648
ARPC1B 669 4856
ARPC2 1357 4617
ARPC3 2873 3762
ARPC4 1698 2568
ARPC5 2295 4844
CACNA1C -762 -668
CACNA1H -5590 -3617
CACNA1S -5579 -4290
CACNB1 -5285 -5348
CACNB3 149 -3506
CAP1 2590 4328
CAP2 -5055 2009
CASC3 9 1880
CDC42 3308 754
CDK5 -1007 -793
CFL1 -909 4720
CLASP1 -3713 1181
CLASP2 2507 -309
CLTA 1218 1668
CLTB -4579 4267
CLTC 2268 -2802
CNTNAP1 -760 -2225
COL4A1 -4755 696
COL4A2 -5035 869
COL4A3 -3831 -4888
COL4A4 -3022 -3981
COL4A5 -4320 -3467
COL6A1 -1945 2037
COL6A2 -1836 2368
COL6A3 -119 2674
COL6A6 -2138 -3974
CREB1 2179 -4329
CSNK2A1 1796 -1733
CSNK2A2 2123 1393
CSNK2B 1917 -296
CUL2 4097 -3317
CXCL12 -4998 -359
CYP51A1 -1716 5047
DAG1 -5236 2687
DLG1 -52 918
DLG3 -1567 -2178
DLG4 -1594 364
DNM1 -747 1193
DNM2 -1149 2166
DNM3 4865 -1268
DOCK1 -226 -41
DOK1 -1380 -974
DOK4 2391 -1860
DOK5 -3981 3669
DPYSL2 -572 4116
DPYSL3 -801 3885
DPYSL5 -4934 2050
DRP2 -4004 511
EFNB1 -2053 3790
EFNB2 4782 1555
EFNB3 -577 637
EGFR 424 1475
EGR2 -3746 5076
EIF4A3 4491 3824
EIF4G1 -2988 -4223
ENAH 4332 5242
EPHA2 -3029 -578
EPHA3 1472 -2138
EPHA4 -3528 207
EPHA7 2741 2897
EPHB1 -3669 -223
EPHB2 -3231 2001
EPHB3 -5580 -1737
EPHB4 606 3837
EPHB6 -1676 -58
ERBB2 -5511 673
ETF1 3946 4969
EVL -3566 2476
EZR -2209 4498
FARP2 -1333 -3397
FAU 2272 4115
FES 559 4512
FGFR1 -1499 -3421
FLRT3 4144 4201
FRS2 4678 761
FYN -2850 3685
GAB1 -1853 -2427
GAB2 4053 2422
GDNF -4043 4741
GFRA1 -4438 -2997
GIT1 -4208 4025
GPC1 -5269 -2966
GRB10 -1615 561
GRB2 -4050 4496
GSK3B 897 3200
GSPT1 1495 -2535
HDAC2 4386 -1101
HFE2 -5332 -5168
HMGCR 971 4631
HRAS -4545 -3997
HSP90AA1 3656 5261
HSP90AB1 -639 4629
HSPA8 3674 5088
IRS2 3384 2684
ITGA1 1757 -4136
ITGA10 -1878 -986
ITGA5 -4752 5178
ITGA9 -5247 3076
ITGAV -819 50
ITGB1 956 4614
ITGB3 -488 4915
ITSN1 524 -4884
KALRN -5340 228
KRAS 3546 4454
L1CAM 945 2245
LAMA2 -3799 -762
LAMB1 -457 -387
LAMC1 -3224 2526
LDB1 -5369 -2642
LIMK1 -4857 4174
LIMK2 -5357 -3206
LYN 785 3984
LYPLA2 -3796 1864
MAGOH 4561 4010
MAGOHB 2239 2185
MAP2K1 -506 -2643
MAP2K2 -3813 -1797
MAPK1 1988 -648
MAPK11 -3385 -333
MAPK12 -5264 644
MAPK14 -1562 -1635
MAPK3 -1024 3725
MAPK7 -729 3565
MAPK8 457 1106
MBP -2415 1151
MET -3529 2929
MMP2 -692 -2003
MSN -3907 4668
MYH10 50 4851
MYH14 -3853 -3913
MYH9 -1879 4194
MYL12A 84 5226
MYL12B 1563 1984
MYL6 -3628 4190
MYL9 -4777 11
MYO10 1381 294
MYO9B -1901 4055
NAB1 -3099 2622
NAB2 -5323 4419
NCAM1 -3954 4132
NCBP1 -1736 4182
NCBP2 4188 264
NCK1 3718 1288
NCK2 -953 -2223
NCSTN -2504 1262
NEO1 -1978 3295
NFASC -2394 602
NRAS 4354 69
NRP1 -112 -4259
NRP2 2152 -2962
NTN1 -3499 244
NTN4 -1261 -948
NUMB 2961 3421
PAK1 -5419 -4885
PAK2 1525 4805
PAK4 -1756 4911
PDLIM7 -5046 -1156
PFN1 467 1712
PFN2 -4209 -3534
PIK3CA 365 2811
PIK3CB 2760 4994
PIK3CD -4322 -4161
PIK3R1 2896 -3147
PIK3R3 3188 577
PIP5K1C -1917 390
PITPNA -2450 -694
PLCG1 -3955 -4939
PLXNA1 -4487 -539
PLXNA2 -5392 3724
PLXNA3 -5112 3055
PLXNA4 -319 -842
PLXNB1 -5451 -1100
PLXNB3 -4041 -4305
PLXNC1 3270 1358
PLXND1 -4476 -3331
PMP22 -1291 1645
PPP3CB -3435 -5065
PRKACA -4691 -1606
PRKACB -2659 -1546
PRKAR2A -2664 -655
PRKCA -2938 -2924
PRKCQ -5095 -4882
PRNP 2908 4942
PRX -2568 1483
PSEN1 2070 2061
PSEN2 -5371 -1458
PSENEN -2638 482
PSMA1 2820 3328
PSMA3 3434 -4
PSMA4 769 958
PSMA6 2199 -1044
PSMA7 -2980 976
PSMB1 954 2628
PSMB10 -1800 2907
PSMB2 618 2471
PSMB4 -235 2096
PSMB5 -4113 -606
PSMB6 -793 914
PSMB7 -831 -1453
PSMB8 -675 2066
PSMB9 -1611 -2973
PSMC1 449 -336
PSMC2 -1311 3241
PSMC3 -2439 -369
PSMC4 2724 1416
PSMC5 1212 -1123
PSMC6 -2520 3423
PSMD1 2619 -1191
PSMD10 -1227 525
PSMD11 995 5183
PSMD12 3831 536
PSMD13 821 1665
PSMD14 -635 3816
PSMD2 -713 -555
PSMD3 -3343 2226
PSMD4 -214 2558
PSMD5 1807 3558
PSMD6 3537 -2207
PSMD7 -2329 1233
PSMD8 -3171 4626
PSMD9 4204 -970
PSME1 -2771 3350
PSME2 -4085 3584
PSME3 3333 3379
PSME4 1960 -4574
PSMF1 683 -1480
PTK2 -2497 -1508
PTPN11 -1575 -666
PTPRA -402 3653
RAC1 2525 1457
RANBP9 4005 219
RAP1GAP -894 -3461
RASA1 -612 -183
RBX1 -733 -968
RDX -562 -4953
RELN 3729 1663
RGMA -661 -293
RGMB -413 -227
RHOA 539 4193
RHOB 4609 5128
RHOC -4944 4715
RND1 3883 5266
RNPS1 681 -379
ROBO1 3700 764
ROBO2 -3259 -3691
ROCK1 4876 -54
ROCK2 2205 314
RPL10 -3902 3841
RPL11 -2249 2690
RPL14 433 1505
RPL18 -1782 3926
RPL18A -2969 1546
RPL19 -502 2402
RPL22 1231 -695
RPL22L1 3380 4103
RPL23 -115 2472
RPL26 1047 3247
RPL28 -391 2871
RPL3 -786 4892
RPL30 286 2070
RPL31 -595 4273
RPL32 -367 2766
RPL34 1447 1856
RPL35A 812 1955
RPL36A 1261 2266
RPL37 -715 2388
RPL37A -1043 2280
RPL38 231 3306
RPL3L -5212 -3395
RPL4 -522 1026
RPL5 1206 4486
RPL7 1440 1916
RPL8 -2775 2474
RPLP2 -2469 2383
RPS11 -1582 3395
RPS12 -318 3958
RPS13 1131 3118
RPS14 -1412 1322
RPS15 -1799 1989
RPS15A -704 2410
RPS16 -1828 3864
RPS18 -974 2916
RPS19 -2045 2954
RPS20 -1844 4785
RPS21 -1536 707
RPS23 -68 1922
RPS24 256 1742
RPS26 -282 2982
RPS27A 783 1840
RPS27L -616 298
RPS29 -1140 2499
RPS3 -544 3102
RPS4X 83 1892
RPS5 -1577 2419
RPS6 -245 3549
RPS6KA1 -1481 -46
RPS6KA2 -4748 -5153
RPS6KA3 952 410
RPS6KA4 -1201 1752
RPS6KA5 51 -5295
RPS8 -1593 2271
RPS9 -1107 1580
RRAS -4504 1351
SCN1B -4899 -5314
SCN2A 544 316
SCN2B -4268 -1921
SCN3A 2439 4422
SCN3B -3892 2980
SCN4A -5601 -5087
SCN5A -5309 3520
SDC2 1756 4483
SDCBP 4377 4839
SEMA3A 2682 1065
SEMA4A 796 3229
SEMA4D -5491 -4922
SEMA5A 485 -2610
SEMA6A 3579 -3659
SEMA6D -3707 -3013
SEMA7A -768 4609
SH3KBP1 1014 -3709
SHANK3 -2640 -2199
SHC1 3976 3605
SIAH1 5006 1408
SIAH2 -1998 5216
SLIT1 -2284 179
SLIT3 -271 1547
SMARCA4 -3874 -1402
SOS1 -1962 -1007
SOS2 -563 -3782
SPTAN1 -2425 -1976
SPTB -5499 -3499
SPTBN1 -2919 -3387
SRC -3910 1378
SREBF2 -4703 4517
SRGAP1 938 747
SRGAP3 -3043 -1274
ST8SIA2 -5423 3963
ST8SIA4 3236 -3584
TEAD1 -4292 -1880
TIAM1 2024 403
TLN1 -3918 2975
TRIO 1163 -2925
TRPC1 1744 -577
UBC 2672 4480
UNC5A -775 -2406
UNC5B -1122 -4255
UPF2 3566 -3399
UPF3A -2545 842
UPF3B 1586 -4316
USP33 2501 -3073
UTRN -3639 -3388
VASP -142 366
VAV2 -4959 -899
VAV3 187 -1063
VLDLR -4564 -5322
WASL 2683 3268
WWTR1 -2503 809
YAP1 -476 3863
YES1 -176 -2941
ZSWIM8 -1026 547



Innate Immune System

Innate Immune System
metric value
setSize 608
pMANOVA 4.07e-13
p.adjustMANOVA 2.39e-11
s.dist 0.173
s.human -0.0431
s.mouse 0.167
p.human 0.0738
p.mouse 4.06e-12




Top 20 genes
Gene human mouse
SERPINB6 -5411 4903
PFKL -4966 4932
SIRPA -5627 4222
VCL -4538 5034
ANXA2 -4123 5025
LIMK1 -4857 4174
PPIA -4031 4697
ALDH3B1 -4529 4142
GRB2 -4050 4496
GALNS -3960 4545
CYB5R3 -5395 3330
BCL2L1 -5181 3434
POLR2L -4314 4110
CKAP4 -3818 4639
AMPD3 -4286 4079
NFKBIA -4263 4096
PRDX6 -3481 4973
VAT1 -4095 4223
ASAH1 -3414 5051
GYG1 -3875 4435

Click HERE to show all gene set members

All member genes
human mouse
AAMP 2657.0 111.0
ABI1 3792.0 2553.0
ABI2 -308.0 5048.0
ABL1 -4533.0 -3545.0
ACLY -2628.0 3492.0
ACTB 940.0 4977.0
ACTG1 -3075.0 4986.0
ACTR10 1853.0 897.0
ACTR1B -4206.0 3803.0
ACTR2 3547.0 3933.0
ACTR3 1376.0 5136.0
ADAM10 -1509.0 -1025.0
ADAM8 -2592.0 5107.0
AGA 1618.0 -4995.0
AGL -4967.0 -5094.0
AGPAT2 -4979.0 -2002.0
AHCYL1 -3386.0 988.0
ALAD -3855.0 -3630.0
ALDH3B1 -4529.0 4142.0
ALDOA -5575.0 -3482.0
ALDOC 1379.0 4707.0
ALPK1 -1737.0 -234.0
AMPD3 -4286.0 4079.0
ANO6 -4134.0 2564.0
ANPEP -215.0 -634.0
ANXA2 -4123.0 5025.0
AP1M1 3732.0 1437.0
AP2A2 -1058.0 5063.0
APAF1 -3469.0 2921.0
APEH -3390.0 -1366.0
APP -2792.0 582.0
APRT -3384.0 -51.0
ARHGAP9 -2941.0 2431.0
ARL8A -4586.0 3346.0
ARMC8 -194.0 -4059.0
ARPC1A -120.0 2648.0
ARPC1B 669.0 4856.0
ARPC2 1357.0 4617.0
ARPC3 2873.0 3762.0
ARPC4 1698.0 2568.0
ARPC5 2295.0 4844.0
ARSA -3312.0 1530.0
ARSB -1001.0 2832.0
ART1 -5553.0 -4799.0
ASAH1 -3414.0 5051.0
ATAD3B 1907.0 -4078.5
ATF1 3129.0 3014.0
ATF2 3130.0 1863.0
ATG12 4060.0 1590.0
ATG5 1661.0 1956.0
ATG7 -1364.0 1374.0
ATOX1 646.0 433.0
ATP11A -1843.0 -4608.0
ATP11B 4841.0 -2179.0
ATP6AP2 2114.0 5158.0
ATP6V0A1 -3809.0 1763.0
ATP6V0A2 186.0 -2715.0
ATP6V0B -3461.0 664.0
ATP6V0D1 -2256.0 4236.0
ATP6V0E1 1861.0 4262.0
ATP6V0E2 -1727.0 -2952.0
ATP6V1A 1633.0 729.0
ATP6V1B2 2299.0 4678.0
ATP6V1C1 3521.0 5003.0
ATP6V1D 3269.0 -2868.0
ATP6V1E1 3913.0 -407.0
ATP6V1F -3562.0 -2379.0
ATP6V1G2 1570.0 -473.0
ATP6V1H -57.0 4488.0
ATP7A 1448.0 -287.0
ATP8A1 1830.0 -3788.0
B2M -731.0 1593.0
B4GALT1 -1314.0 2589.0
BAIAP2 -641.0 5041.0
BCL10 4124.0 4239.0
BCL2 -4633.0 -1108.0
BCL2L1 -5181.0 3434.0
BIRC2 3739.0 -2890.0
BIRC3 -4741.0 978.0
BRI3 -3525.0 -1234.0
BRK1 2026.0 3096.0
BTRC -1187.0 -2758.0
C1R -813.0 -1019.0
C1S -2427.0 -2050.0
C2 -558.0 -1359.0
C3 4311.0 1838.0
C6orf120 1881.0 2354.0
C7 -1128.0 1335.0
CAB39 2485.0 2704.0
CALM1 -4464.0 96.0
CAND1 3370.0 4369.0
CANT1 511.0 1963.0
CAP1 2590.0 4328.0
CAPN1 -5166.0 -4425.0
CAPZA2 -1777.0 -3734.0
CASP1 -1298.0 3173.0
CASP2 2946.0 -3849.0
CASP8 -1646.0 3092.0
CASP9 -3269.0 -2569.0
CAT -4828.0 -4266.0
CCT2 3805.0 4207.0
CCT8 4149.0 3796.0
CD36 -582.0 -3838.0
CD44 837.0 4987.0
CD46 1543.0 -3487.0
CD47 -2184.0 2680.0
CD55 220.0 -323.0
CD59 1637.0 -4378.0
CD63 -3297.0 4594.0
CD81 -4675.0 895.0
CDC34 -2923.0 -2346.0
CDC42 3308.0 754.0
CDK13 4123.0 1830.0
CEP290 3352.0 -4522.0
CFH -556.0 -115.0
CFL1 -909.0 4720.0
CHUK 216.0 955.0
CKAP4 -3818.0 4639.0
CLU 1629.0 4164.0
CMTM6 2331.0 4071.0
CNN2 -4870.0 2117.0
CNPY3 -3045.0 3021.0
COMMD3 246.0 -1247.0
COMMD9 385.0 1630.0
COPB1 3916.0 4572.0
COTL1 -1553.0 5172.0
CPNE3 1228.0 -3452.0
CPPED1 -3625.0 -4900.0
CRCP 1806.0 -883.0
CREB1 2179.0 -4329.0
CREBBP 1506.0 3139.0
CREG1 1430.0 -1124.0
CRISPLD2 -871.0 -3137.0
CRK 2145.0 2262.0
CSNK2B 1917.0 -296.0
CSTB -3426.0 4748.0
CTNNB1 1714.0 -780.0
CTSA -3537.0 -2181.0
CTSB -1198.0 -795.0
CTSC 2720.0 2417.0
CTSD -4817.0 -4037.0
CTSH -3465.0 3123.0
CTSK 2.0 263.0
CTSS -339.0 5084.0
CTSV 2209.0 34.0
CTSZ -3890.0 3389.0
CUL1 -3121.0 -1536.0
CYB5R3 -5395.0 3330.0
CYBA -633.0 3083.0
CYBB -2550.0 3579.0
CYFIP2 -3775.0 -1129.0
CYLD -1990.0 2392.0
CYSTM1 -1304.0 1985.0
DBNL -2320.0 4579.0
DDOST 320.0 4699.0
DDX3X 4686.0 4170.0
DDX41 273.0 705.0
DDX58 1593.0 -909.0
DEGS1 -2228.0 3767.0
DERA 3823.0 1200.0
DGAT1 -2804.0 -1001.0
DHX36 3822.0 -3595.0
DHX58 -2934.0 1196.0
DHX9 4151.0 322.0
DIAPH1 3282.0 5032.0
DNAJC13 1888.0 -3638.0
DNAJC3 1950.0 1334.0
DNAJC5 -2830.0 1053.0
DNASE1L1 -5205.0 -5289.0
DNM1 -747.0 1193.0
DNM2 -1149.0 2166.0
DNM3 4865.0 -1268.0
DOCK1 -226.0 -41.0
DOK3 -5498.0 3093.0
DPP7 -4199.0 2087.0
DSN1 2075.0 534.0
DTX4 4372.0 -2645.0
DUSP3 -5149.0 -5173.0
DUSP4 -3613.0 3013.0
DUSP6 -528.0 -1256.0
DUSP7 -3477.0 -3537.0
DYNC1H1 -1442.0 -2348.0
DYNC1LI1 2883.0 1316.0
DYNLL1 -1331.0 4245.0
DYNLT1 2579.0 1650.0
ECSIT -2655.0 -2846.0
EEA1 1370.0 1624.0
EEF1A1 -2150.0 2931.0
EEF2 -2853.0 -853.0
ELK1 -3862.0 -42.0
ELMO1 -2166.0 1449.0
ELMO2 -354.0 416.0
ENPP4 -1280.0 -3299.0
EP300 3403.0 -1622.0
ERP44 2150.0 2698.0
FABP5 -338.0 -519.0
FADD -571.0 4877.0
FAF2 3890.0 3211.0
FBXW11 4385.0 4535.0
FGL2 -1862.0 3038.0
FOS 1865.0 5273.0
FRK 194.0 -2049.0
FTH1 -1890.0 -127.0
FUCA1 111.0 1320.0
FUCA2 -2160.0 -4180.0
FYN -2850.0 3685.0
GAA -5001.0 -3369.0
GAB2 4053.0 2422.0
GALNS -3960.0 4545.0
GCA 2461.0 -4105.0
GDI2 865.0 4849.0
GGH 3482.0 1046.0
GHDC -3542.0 -4089.0
GLA 3418.0 -1853.0
GLB1 -2244.0 924.0
GM2A -1169.0 2670.0
GNS 101.0 -979.0
GOLGA7 1185.0 2077.0
GPI -5210.0 -4132.0
GRB2 -4050.0 4496.0
GRN -4029.0 2537.0
GSDMD -2517.0 3392.0
GSN 72.0 -256.0
GUSB 1923.0 4153.0
GYG1 -3875.0 4435.0
HEXB 753.0 2379.0
HGSNAT -4600.0 -3529.0
HMGB1 -2199.0 -1662.0
HMOX2 -687.0 552.0
HRAS -4545.0 -3997.0
HSP90AA1 3656.0 5261.0
HSP90AB1 -639.0 4629.0
HSP90B1 460.0 4944.0
HSPA1A 4887.0 5277.5
HSPA1B 4676.0 5277.5
HSPA8 3674.0 5088.0
HUWE1 -673.0 -4013.0
HVCN1 -2318.0 -2383.0
ICAM2 -1505.0 -3478.0
IDH1 1160.0 -5189.0
IFI16 -1127.0 4923.5
IFIH1 -204.0 -3116.0
IGF2R -2030.0 -1074.0
IKBKB -4093.0 578.0
ILF2 4835.0 4254.0
IMPDH1 -827.0 2546.0
IMPDH2 822.0 1907.0
IQGAP1 -415.0 3217.0
IRAK1 -4351.0 -480.0
IRAK2 -4255.0 3633.0
IRAK3 95.0 1688.0
IRAK4 -569.0 1975.0
IRF3 -3061.0 -114.0
IRF7 775.0 4030.0
ISG15 -3928.0 1737.0
IST1 3827.0 4131.0
ITCH 4319.0 -2959.0
ITGAM -2633.0 5045.0
ITGAV -819.0 50.0
ITGAX -896.0 3851.0
ITGB2 -107.0 4993.0
ITPR1 4903.0 -2230.0
ITPR2 1242.0 -3115.0
ITPR3 -3631.0 -3441.0
JUN 2469.0 5225.0
JUP 1723.0 4368.0
KCMF1 501.0 -1005.0
KCNAB2 -3198.0 5020.0
KPNB1 3619.0 3517.0
KRAS 3546.0 4454.0
LAMP1 764.0 -2637.0
LAMP2 -2579.0 848.0
LAMTOR1 -800.0 -2671.0
LAMTOR2 -1715.0 -424.0
LAMTOR3 3134.0 3162.0
LAT2 -1020.0 4497.0
LGALS3 1062.0 4809.0
LGMN 4834.0 4463.0
LIMK1 -4857.0 4174.0
LPCAT1 -1659.0 2005.0
LRRFIP1 -4175.0 -4627.0
LTA4H 1584.0 4089.0
LYN 785.0 3984.0
MAGT1 1192.0 -1341.0
MALT1 -2616.0 -3568.0
MAN2B1 -3000.0 331.0
MANBA -1928.0 -2694.0
MAP2K1 -506.0 -2643.0
MAP2K3 -4716.0 3039.0
MAP2K4 8.0 -3251.0
MAP2K6 1456.0 -4876.0
MAP2K7 794.0 -3887.0
MAP3K1 1124.0 -3440.0
MAP3K7 2142.0 -4056.0
MAP3K8 344.0 4159.0
MAPK1 1988.0 -648.0
MAPK10 -3504.0 -1859.0
MAPK11 -3385.0 -333.0
MAPK12 -5264.0 644.0
MAPK14 -1562.0 -1635.0
MAPK3 -1024.0 3725.0
MAPK7 -729.0 3565.0
MAPK8 457.0 1106.0
MAPK9 -3854.0 -3511.0
MAPKAPK2 -2489.0 -645.0
MAPKAPK3 -4795.0 -3142.0
MASP1 -4224.0 -1589.0
MAVS -4768.0 -4861.0
MEF2A -5175.0 -4103.0
MEF2C -4610.0 -2794.0
METTL7A -5605.0 -5247.0
MGST1 427.0 -2546.0
MIF -2307.0 2943.0
MLEC -3173.0 -5166.0
MME -3346.0 -3103.0
MOSPD2 3720.0 -2512.0
MVP -4506.0 2829.0
MYD88 2726.0 4679.0
MYH2 -3080.0 -857.0
MYH9 -1879.0 4194.0
MYO10 1381.0 294.0
MYO1C -4842.0 3521.0
MYO5A -885.0 3279.0
MYO9B -1901.0 4055.0
NBEAL2 -4727.0 -339.0
NCK1 3718.0 1288.0
NCKAP1 3563.0 3585.0
NCKIPSD -2821.0 704.0
NCSTN -2504.0 1262.0
NDUFC2 34.0 -2430.0
NEU1 1863.0 4218.0
NF2 -1449.0 -4728.0
NFASC -2394.0 602.0
NFATC1 -5337.0 -1304.0
NFATC2 -3264.0 3355.0
NFATC3 -3321.0 -2944.0
NFKB1 -4233.0 3315.0
NFKB2 -3926.0 3336.0
NFKBIA -4263.0 4096.0
NFKBIB 4450.0 3578.0
NHLRC3 -3747.0 2370.0
NIT2 -1606.0 -943.0
NKIRAS1 4369.0 -2967.0
NKIRAS2 -1369.0 2403.0
NLRC3 -2924.0 1084.0
NLRC5 -4398.0 2653.0
NLRX1 -4825.0 -4899.0
NOD1 -3886.0 -3144.0
NOD2 -4402.0 1776.0
NOS1 -4260.0 -4935.0
NPC2 790.0 2258.0
NRAS 4354.0 69.0
ORMDL3 893.0 3912.0
OSTF1 2228.0 2902.0
OTUD5 4179.0 2823.0
PADI2 -5625.0 -4599.0
PAFAH1B2 3709.0 4387.0
PAK1 -5419.0 -4885.0
PAK2 1525.0 4805.0
PANX1 1142.0 1062.0
PDAP1 -1236.0 1825.0
PDPK1 3443.0 2222.0
PDXK -4690.0 -834.0
PDZD11 1678.0 490.0
PELI1 4489.0 4759.0
PELI2 3371.0 -1012.0
PELI3 -4396.0 795.0
PFKL -4966.0 4932.0
PGM1 -4270.0 -4493.0
PGM2 -561.0 3964.0
PGRMC1 -333.0 1308.0
PIK3C3 3439.0 -1648.0
PIK3CA 365.0 2811.0
PIK3CB 2760.0 4994.0
PIK3R1 2896.0 -3147.0
PIK3R4 3839.0 -3531.0
PIN1 -3515.0 1213.0
PKM -4231.0 -4264.0
PLA2G6 -3913.0 -525.0
PLAU -548.0 1192.0
PLAUR -638.0 3744.0
PLCG1 -3955.0 -4939.0
PLD1 55.0 -779.0
PLD2 -60.0 -4810.0
PLD3 -5217.0 573.0
PLEKHO2 -717.0 3402.0
PNP 5019.5 4586.0
POLR1C 3643.0 4119.0
POLR1D 413.0 1462.0
POLR2E -667.0 1599.0
POLR2H -3927.0 3497.0
POLR2K 2480.0 -1584.0
POLR2L -4314.0 4110.0
POLR3A 4348.0 -4076.0
POLR3B 2547.0 -3390.0
POLR3C 4052.0 3012.0
POLR3D 381.0 1468.0
POLR3E 1908.0 -1229.0
POLR3F 4054.0 2443.0
POLR3G 1455.0 3367.0
POLR3GL -1424.0 -3192.0
POLR3H 282.0 2294.0
POLR3K 4716.0 -3105.0
PPIA -4031.0 4697.0
PPIE 2144.0 896.0
PPP2CA 4482.0 3008.0
PPP2CB 2458.0 4129.0
PPP2R1A -4013.0 -696.0
PPP2R1B 3028.0 4619.0
PPP2R5D -3449.0 -2058.0
PPP3CA 109.0 -2737.0
PPP3CB -3435.0 -5065.0
PRCP 970.0 870.0
PRDX4 132.0 2521.0
PRDX6 -3481.0 4973.0
PRKACA -4691.0 -1606.0
PRKACB -2659.0 -1546.0
PRKCD -4276.0 3377.0
PRKCE -4307.0 -3088.0
PRKCQ -5095.0 -4882.0
PRKCSH -268.0 539.0
PRKDC 2294.0 -3033.0
PROS1 103.0 2938.0
PSAP -2247.0 -4040.0
PSEN1 2070.0 2061.0
PSMA1 2820.0 3328.0
PSMA3 3434.0 -4.0
PSMA4 769.0 958.0
PSMA6 2199.0 -1044.0
PSMA7 -2980.0 976.0
PSMB1 954.0 2628.0
PSMB10 -1800.0 2907.0
PSMB2 618.0 2471.0
PSMB4 -235.0 2096.0
PSMB5 -4113.0 -606.0
PSMB6 -793.0 914.0
PSMB7 -831.0 -1453.0
PSMB8 -675.0 2066.0
PSMB9 -1611.0 -2973.0
PSMC1 449.0 -336.0
PSMC2 -1311.0 3241.0
PSMC3 -2439.0 -369.0
PSMC4 2724.0 1416.0
PSMC5 1212.0 -1123.0
PSMC6 -2520.0 3423.0
PSMD1 2619.0 -1191.0
PSMD10 -1227.0 525.0
PSMD11 995.0 5183.0
PSMD12 3831.0 536.0
PSMD13 821.0 1665.0
PSMD14 -635.0 3816.0
PSMD2 -713.0 -555.0
PSMD3 -3343.0 2226.0
PSMD4 -214.0 2558.0
PSMD5 1807.0 3558.0
PSMD6 3537.0 -2207.0
PSMD7 -2329.0 1233.0
PSMD8 -3171.0 4626.0
PSMD9 4204.0 -970.0
PSME1 -2771.0 3350.0
PSME2 -4085.0 3584.0
PSME3 3333.0 3379.0
PSME4 1960.0 -4574.0
PSMF1 683.0 -1480.0
PTGES2 -2699.0 -3434.0
PTK2 -2497.0 -1508.0
PTPN11 -1575.0 -666.0
PTPN4 -1408.0 3737.0
PTPN6 -931.0 4799.0
PTPRB -4654.0 -4596.0
PTPRJ 391.0 3748.0
PTX3 -1790.0 728.0
PYCARD -2810.0 4703.0
PYGB -4498.0 1915.0
PYGL -3546.0 4121.0
QPCT 250.0 4615.0
QSOX1 2045.0 2998.0
RAB10 -2646.0 -3853.0
RAB14 2341.0 -844.0
RAB18 4588.0 -4361.0
RAB24 -1792.0 -4677.0
RAB27A 169.0 1070.0
RAB31 -547.0 4084.0
RAB3A 75.0 -3951.0
RAB3D 3527.0 1980.0
RAB5B 584.0 -3464.0
RAB5C 2317.0 3393.0
RAB7A -383.0 1499.0
RAC1 2525.0 1457.0
RAC2 41.0 4946.0
RAF1 1712.0 -1646.0
RAP1A -689.0 3710.0
RAP1B 4479.0 4565.0
RAP2B 3971.0 4705.0
RAP2C -983.0 -2112.0
RASGRP2 -2556.0 -4280.0
RELA 1783.0 4531.0
RELB -2305.0 3391.0
RHOA 539.0 4193.0
RHOG -1207.0 4926.0
RIPK1 325.0 719.0
RIPK2 3609.0 4837.0
RNASET2 -4153.0 1724.0
RNF125 3620.0 -1830.0
RNF135 -3677.0 989.0
RNF216 -4323.0 2090.0
ROCK1 4876.0 -54.0
RPS27A 783.0 1840.0
RPS6KA1 -1481.0 -46.0
RPS6KA2 -4748.0 -5153.0
RPS6KA3 952.0 410.0
RPS6KA5 51.0 -5295.0
S100A1 -4789.0 -517.0
S100A11 -3518.0 4650.0
SCAMP1 -549.0 1634.0
SDCBP 4377.0 4839.0
SERPINB1 1882.0 5166.0
SERPINB6 -5411.0 4903.0
SERPING1 78.0 286.0
SHC1 3976.0 3605.0
SIGIRR -452.0 -1704.0
SIKE1 -73.0 -2325.0
SIRPA -5627.0 4222.0
SKP1 2028.0 -2504.0
SLC15A4 -527.0 856.0
SLC2A3 5004.0 2971.5
SLC44A2 -5438.0 -4740.0
SNAP23 372.0 -209.0
SNAP29 -2698.0 1321.0
SOCS1 199.0 4033.0
SOS1 -1962.0 -1007.0
SPTAN1 -2425.0 -1976.0
SRC -3910.0 1378.0
SRP14 2888.0 -1495.0
STAT6 -5317.0 -1263.0
STK10 -3246.0 1353.0
STK11IP -451.0 -2797.0
STOM 2424.0 4434.0
SUGT1 3140.0 -4533.0
SURF4 1238.0 3721.0
SVIP 3363.0 -4988.0
SYNGR1 -4900.0 -5133.0
TAB1 -4874.0 -4753.0
TAB2 2791.0 681.0
TAB3 2116.0 4834.0
TANK 3655.0 3446.0
TAX1BP1 3222.0 -1141.0
TBK1 673.0 3485.0
TCIRG1 -3600.0 4552.0
TEC 3728.0 2609.0
TICAM1 1624.0 4371.0
TIFA -1142.0 -118.0
TIMP2 -1886.0 -738.0
TIRAP -2943.0 -3631.0
TLR3 -310.0 -3710.0
TLR4 1065.0 4916.0
TLR5 -3234.0 927.0
TLR6 888.0 1296.0
TMBIM1 -4812.0 3552.0
TMC6 -4677.0 -1324.0
TMEM30A 2855.0 -2390.0
TMEM63A -4829.0 841.0
TNFAIP3 -5203.0 1811.0
TNFAIP6 1870.0 3235.0
TNFRSF1B -874.0 4595.0
TNIP2 -1370.0 3203.0
TOLLIP -256.0 1337.0
TOM1 -5386.0 -3241.0
TRAF2 -1546.0 980.0
TRAF3 -3815.0 2462.0
TRAF6 3468.0 1207.0
TRAPPC1 368.0 -653.0
TRIM21 2960.0 -747.0
TRIM25 -3243.0 -119.0
TRIM32 1027.0 3819.0
TRIM56 -3368.0 -2537.0
TSPAN14 -4941.0 -1469.0
TUBB -3118.0 5070.0
TUBB4B 430.0 4896.0
TXN 1855.0 4791.0
UBA3 3512.0 2083.0
UBA7 -1671.0 -2769.0
UBC 2672.0 4480.0
UBE2D1 -1588.0 -4032.0
UBE2D2 -1986.0 3383.0
UBE2D3 1424.0 4934.0
UBE2K 1393.0 3662.0
UBE2L6 -3548.0 4613.0
UBE2M 1247.0 1561.0
UBE2N 2545.0 3996.0
UBR4 2440.0 -3370.0
VAMP8 -2728.0 -3233.0
VAPA 2838.0 2906.0
VAT1 -4095.0 4223.0
VAV2 -4959.0 -899.0
VAV3 187.0 -1063.0
VCL -4538.0 5034.0
VRK3 464.0 -1371.0
WASF2 -4656.0 1511.0
WASF3 -1015.0 718.0
WASL 2683.0 3268.0
WIPF1 -2552.0 1682.0
WIPF2 3299.0 -502.0
WIPF3 -5107.0 -5055.0
XRCC5 4010.0 -2853.0
XRCC6 3225.0 -1241.0
YES1 -176.0 -2941.0
YPEL5 4366.0 3599.0



Cytokine Signaling in Immune system

Cytokine Signaling in Immune system
metric value
setSize 518
pMANOVA 5.88e-13
p.adjustMANOVA 3.3e-11
s.dist 0.188
s.human -0.0275
s.mouse 0.186
p.human 0.291
p.mouse 8.82e-13




Top 20 genes
Gene human mouse
CDKN1A -4927 5092
VCL -4538 5034
DUSP2 -4253 5104
ANXA2 -4123 5025
MID1 -4726 4300
STAT3 -3885 5061
GDNF -4043 4741
PPIA -4031 4697
CSF1 -4242 4358
EDA2R -4901 3755
TRIM62 -4984 3681
MSN -3907 4668
GRB2 -4050 4496
IL6R -5515 3267
BCL2L1 -5181 3434
NFKBIA -4263 4096
CSK -3610 4738
IL4R -3335 4935
UBE2L6 -3548 4613
NCAM1 -3954 4132

Click HERE to show all gene set members

All member genes
human mouse
AAAS -3476 1550
ABCE1 4707 572
ABHD17A -1525 -161
ABHD17B 1639 1020
ABHD17C -2092 2958
ACTN2 -3104 3454
ADAM17 2407 2079
ADAR -3014 420
AIP -707 -1563
AKT1 -4954 342
AKT2 -4057 -4450
ANGPT1 -853 -4174
ANXA1 537 4544
ANXA2 -4123 5025
APP -2792 582
ARAF -3318 -4367
ARF1 566 4500
ARIH1 4268 2886
ARL2 -4142 -523
ARRB1 -3133 -14
ARRB2 -1089 4317
ATF1 3129 3014
ATF2 3130 1863
B2M -731 1593
BCL2 -4633 -1108
BCL2L1 -5181 3434
BCL6 -5018 -4816
BIRC2 3739 -2890
BIRC3 -4741 978
BRAF 4103 1387
BRAP 4689 3899
BRWD1 2271 -4063
BTRC -1187 -2758
CALM1 -4464 96
CAMK2A -5527 -4430
CAMK2B -5497 -4230
CAMK2D -2223 4137
CAMK2G -2097 -4962
CANX -836 4736
CASP1 -1298 3173
CASP3 423 5016
CBL 1736 183
CCL2 2620 5111
CCND1 757 529
CD36 -582 -3838
CD44 837 4987
CDC42 3308 754
CDKN1A -4927 5092
CFL1 -909 4720
CHUK 216 955
CLCF1 -2419 2301
CNKSR1 -2870 3756
CNN2 -4870 2117
COL1A2 -1712 -377
CREB1 2179 -4329
CRK 2145 2262
CRKL -91 4314
CRLF1 42 1779
CSF1 -4242 4358
CSK -3610 4738
CTF1 -3242 -4624
CUL1 -3121 -1536
CUL3 2833 -224
DAB2IP -5036 810
DDX58 1593 -909
DLG1 -52 918
DLG3 -1567 -2178
DLG4 -1594 364
DUSP1 -219 4494
DUSP10 -5329 2114
DUSP16 3082 2356
DUSP2 -4253 5104
DUSP3 -5149 -5173
DUSP4 -3613 3013
DUSP5 4084 5213
DUSP6 -528 -1256
DUSP7 -3477 -3537
DUSP8 1715 4654
EDA -124 1970
EDA2R -4901 3755
EGF -4568 -5354
EGFR 424 1475
EGR1 4164 5238
EIF2AK2 -486 -749
EIF4A1 2916 5133
EIF4A2 1360 1839
EIF4A3 4491 3824
EIF4E 2892 3735
EIF4E2 -2440 3158
EIF4E3 -2251 -1876
EIF4G1 -2988 -4223
EIF4G2 1963 -554
EIF4G3 -2799 -3576
ELK1 -3862 -42
ERBB2 -5511 673
ERBB3 -5290 -2790
F13A1 -2059 3642
FBXW11 4385 4535
FGF1 798 5215
FGF2 751 -1095
FGF7 -5445 2606
FGF9 -5320 -3468
FGFR1 -1499 -3421
FGFR3 3759 4128
FGFR4 -5312 -3374
FLNA -3248 3245
FLNB 2772 1024
FN1 35 4022
FNTA 1578 -1804
FNTB -690 2634
FOS 1865 5273
FOXO1 -432 1302
FOXO3 -42 -1131
FRS2 4678 761
FRS3 1398 1971
FSCN1 1705 -932
FYN -2850 3685
GAB1 -1853 -2427
GAB2 4053 2422
GBP6 -2110 -3927
GDNF -4043 4741
GFRA1 -4438 -2997
GHR 3997 -4645
GOLGA7 1185 2077
GRB2 -4050 4496
GSTO1 -2055 -2038
HBEGF 3484 5272
HIF1A -1016 5007
HMGB1 -2199 -1662
HMOX1 -2843 5071
HNRNPA2B1 3693 -2053
HNRNPF 4978 4644
HRAS -4545 -3997
HSP90AA1 3656 5261
HSP90B1 460 4944
HSPA8 3674 5088
HSPA9 2342 -1431
ICAM1 1056 4172
ICMT -2315 -1731
IFI27 -1101 -399
IFI35 -3310 174
IFIT2 -1338 802
IFIT3 -792 1422
IFITM1 1574 4815
IFITM2 -316 4815
IFITM3 380 4815
IFNAR1 3645 1085
IFNAR2 -1316 2360
IFNGR1 2506 2475
IFNGR2 -386 -4286
IKBKB -4093 578
IL10RB 1239 3244
IL11RA -5610 -2978
IL13RA1 -1847 4516
IL15 -2409 -2685
IL16 -1613 -1365
IL17RA 219 4833
IL17RC -4271 1044
IL17RD -3179 -934
IL17RE -1865 -4593
IL18BP 292 2178
IL1R1 -3018 3910
IL1RAP 627 3712
IL20RB -159 -902
IL2RG -1943 3730
IL33 1864 3608
IL34 3060 -1540
IL4R -3335 4935
IL6R -5515 3267
IL6ST 3055 -2364
INPP5D -2433 4327
INPPL1 -5220 -4249
IP6K2 3404 -661
IQGAP1 -415 3217
IRAK1 -4351 -480
IRAK2 -4255 3633
IRAK3 95 1688
IRAK4 -569 1975
IRF1 -1565 984
IRF2 -3387 2261
IRF3 -3061 -114
IRF4 -1166 2585
IRF7 775 4030
IRF9 1267 132
IRS1 -5550 -5121
IRS2 3384 2684
ISG15 -3928 1737
ITGAM -2633 5045
ITGAX -896 3851
ITGB1 956 4614
ITGB2 -107 4993
ITGB3 -488 4915
JAK1 -1869 4228
JAK2 -2569 -5057
JUN 2469 5225
JUNB -2593 5221
KBTBD7 1566 3587
KITLG 4898 -4811
KPNA1 1833 3439
KPNA2 5007 3593
KPNA3 -2337 -1621
KPNA4 1501 4518
KPNB1 3619 3517
KRAS 3546 4454
KSR1 -5578 -5013
LAMA5 -5584 -2744
LAMTOR2 -1715 -424
LAMTOR3 3134 3162
LIFR -994 -4795
LMNB1 3392 2947
LTBR -4989 1241
LYN 785 3984
LYPLA1 1177 -3760
MAOA -96 3927
MAP2K1 -506 -2643
MAP2K2 -3813 -1797
MAP2K3 -4716 3039
MAP2K4 8 -3251
MAP2K6 1456 -4876
MAP2K7 794 -3887
MAP3K11 -3624 1948
MAP3K3 2825 757
MAP3K7 2142 -4056
MAP3K8 344 4159
MAPK1 1988 -648
MAPK10 -3504 -1859
MAPK11 -3385 -333
MAPK12 -5264 644
MAPK14 -1562 -1635
MAPK3 -1024 3725
MAPK7 -729 3565
MAPK8 457 1106
MAPK9 -3854 -3511
MAPKAPK2 -2489 -645
MAPKAPK3 -4795 -3142
MARK3 3178 -2043
MCL1 2837 4826
MEF2A -5175 -4103
MEF2C -4610 -2794
MET -3529 2929
MID1 -4726 4300
MIF -2307 2943
MMP2 -692 -2003
MRAS -5239 941
MSN -3907 4668
MTAP -2515 -2196
MX1 -1867 3219
MYC 3994 4886
MYD88 2726 4679
NCAM1 -3954 4132
NDC1 1273 -2350
NDN 1146 1877
NEDD4 4583 -4838
NF1 3095 3333
NFKB1 -4233 3315
NFKB2 -3926 3336
NFKBIA -4263 4096
NFKBIB 4450 3578
NKIRAS1 4369 -2967
NKIRAS2 -1369 2403
NOD1 -3886 -3144
NOD2 -4402 1776
NRAS 4354 69
NUP107 3232 2949
NUP133 889 -4048
NUP153 4762 1533
NUP155 4306 -2233
NUP160 3998 1035
NUP188 2117 3830
NUP205 4438 3588
NUP214 3124 665
NUP35 4571 649
NUP37 -327 192
NUP43 4562 2216
NUP54 4508 3831
NUP85 3181 -393
NUP88 1244 2212
NUP93 -1503 3903
NUP98 4235 5066
OAS2 212 2064
OSMR 255 4589
P4HB -2525 4048
PAK2 1525 4805
PAQR3 396 3865
PDCD4 2217 1037
PDE12 4844 3597
PDE6D -2753 4470
PDGFA -4328 -4456
PDGFB -606 3347
PDGFRA 2727 -349
PDGFRB -2260 1386
PDPK1 3443 2222
PEA15 -1982 1596
PEBP1 -3678 -1052
PELI1 4489 4759
PELI2 3371 -1012
PELI3 -4396 795
PHB -586 -2116
PIAS1 57 -2190
PIK3C3 3439 -1648
PIK3CA 365 2811
PIK3CB 2760 4994
PIK3CD -4322 -4161
PIK3R1 2896 -3147
PIK3R3 3188 577
PIK3R4 3839 -3531
PIM1 -228 4294
PIN1 -3515 1213
PITPNA -2450 -694
PLCG1 -3955 -4939
PML 3338 3449
POU2F1 3019 -3333
PPIA -4031 4697
PPM1B 4912 1319
PPP1CB -1374 -4149
PPP1CC 4081 399
PPP2CA 4482 3008
PPP2CB 2458 4129
PPP2R1A -4013 -696
PPP2R1B 3028 4619
PPP2R5A 4590 4219
PPP2R5B -1524 121
PPP2R5C -2508 -3684
PPP2R5D -3449 -2058
PPP2R5E 4644 1539
PPP5C -4582 -1815
PRKACA -4691 -1606
PRKCD -4276 3377
PRKCQ -5095 -4882
PSMA1 2820 3328
PSMA3 3434 -4
PSMA4 769 958
PSMA6 2199 -1044
PSMA7 -2980 976
PSMB1 954 2628
PSMB10 -1800 2907
PSMB2 618 2471
PSMB4 -235 2096
PSMB5 -4113 -606
PSMB6 -793 914
PSMB7 -831 -1453
PSMB8 -675 2066
PSMB9 -1611 -2973
PSMC1 449 -336
PSMC2 -1311 3241
PSMC3 -2439 -369
PSMC4 2724 1416
PSMC5 1212 -1123
PSMC6 -2520 3423
PSMD1 2619 -1191
PSMD10 -1227 525
PSMD11 995 5183
PSMD12 3831 536
PSMD13 821 1665
PSMD14 -635 3816
PSMD2 -713 -555
PSMD3 -3343 2226
PSMD4 -214 2558
PSMD5 1807 3558
PSMD6 3537 -2207
PSMD7 -2329 1233
PSMD8 -3171 4626
PSMD9 4204 -970
PSME1 -2771 3350
PSME2 -4085 3584
PSME3 3333 3379
PSME4 1960 -4574
PSMF1 683 -1480
PTK2 -2497 -1508
PTK2B -2461 3862
PTPN1 1531 4585
PTPN11 -1575 -666
PTPN12 4141 5021
PTPN13 4200 -863
PTPN14 1287 -3965
PTPN18 -4024 2425
PTPN2 4314 4306
PTPN23 1152 5065
PTPN3 2224 -5244
PTPN4 -1408 3737
PTPN6 -931 4799
PTPN9 -1215 2535
PTPRA -402 3653
RAE1 4471 2389
RAF1 1712 -1646
RALA -1368 504
RALGDS -5190 -623
RANBP2 4470 -3848
RANBP9 4005 219
RAP1A -689 3710
RAP1B 4479 4565
RAPGEF1 -3992 3326
RAPGEF2 4504 -3856
RASA1 -612 -183
RASA2 3565 62
RASA3 -4990 -756
RASAL2 3510 -2420
RASGRF2 4373 -3165
RASGRP3 -4774 -5308
RBX1 -733 -968
RCE1 2361 3617
RELA 1783 4531
RELB -2305 3391
RGL1 -161 307
RGL2 -4344 -3999
RHOU -4229 -325
RIPK2 3609 4837
RNASEL 2906 878
RORA -5056 -2699
RORC -5248 -4317
RPS27A 783 1840
RPS6KA1 -1481 -46
RPS6KA2 -4748 -5153
RPS6KA3 952 410
RPS6KA5 51 -5295
S1PR1 2689 1552
SAMHD1 48 3058
SDC1 -2046 212
SEC13 730 1702
SEH1L 1085 4263
SH2B1 -3841 -971
SHC1 3976 3605
SHC2 -3710 1658
SHOC2 4514 2152
SIGIRR -452 -1704
SKP1 2028 -2504
SMAD3 -3794 -5343
SMARCA4 -3874 -1402
SNRPA1 4117 4600
SOCS1 199 4033
SOCS3 -283 5103
SOCS5 4145 1886
SOD1 157 807
SOD2 -1568 -3943
SOS1 -1962 -1007
SOS2 -563 -3782
SPRED1 3312 3519
SPRED2 1200 -423
SPRED3 -2447 -1440
SPTAN1 -2425 -1976
SPTB -5499 -3499
SPTBN1 -2919 -3387
SQSTM1 -3803 3545
SRC -3910 1378
STAT1 236 -1738
STAT2 -2601 280
STAT3 -3885 5061
STAT5A -4125 -4573
STAT5B -5022 -5306
STAT6 -5317 -1263
STX1A -411 1613
STX3 4376 -2465
STX4 -2347 78
SUMO1 4213 1399
SYNGAP1 -3658 1029
TAB1 -4874 -4753
TAB2 2791 681
TAB3 2116 4834
TALDO1 -2080 -766
TBK1 673 3485
TCP1 4480 1210
TEC 3728 2609
TEK 3580 -2188
TGFB1 -3111 4943
THEM4 -3616 -500
TIMP1 -1317 5239
TLN1 -3918 2975
TNFRSF12A 1487 5169
TNFRSF14 -3195 -130
TNFRSF1A -4666 3362
TNFRSF1B -874 4595
TNFRSF25 -3839 -3126
TNFSF12 -5179 -2442
TNIP2 -1370 3203
TOLLIP -256 1337
TP53 575 3751
TPR 2984 -1026
TRAF2 -1546 980
TRAF3 -3815 2462
TRAF6 3468 1207
TRIB3 -1004 3791
TRIM2 28 1777
TRIM21 2960 -747
TRIM25 -3243 -119
TRIM26 2745 1821
TRIM3 -1373 2035
TRIM35 3906 -2312
TRIM45 -2733 4282
TRIM5 1812 -4581
TRIM62 -4984 3681
TRIM68 3519 -4830
TRIM8 -5354 2384
TWIST1 2624 2962
TXLNA -3216 2707
TYK2 -3123 -50
UBA3 3512 2083
UBA7 -1671 -2769
UBC 2672 4480
UBE2E1 -1132 -479
UBE2L6 -3548 4613
UBE2M 1247 1561
UBE2N 2545 3996
USP18 45 -2568
VAMP2 -3293 1812
VAMP7 2376 -4569
VCAM1 2866 4713
VCL -4538 5034
VEGFA -4571 -5196
VIM -3027 4772
VRK3 464 -1371
VWF -779 -106
WDR83 1010 -3888
XAF1 -320 -1153
YES1 -176 -2941
YWHAB 3680 3415
YWHAZ 2019 4495
ZDHHC9 -3396 1619
ZEB1 -4223 -195



Influenza Infection

Influenza Infection
metric value
setSize 107
pMANOVA 7.65e-13
p.adjustMANOVA 4.1e-11
s.dist 0.44
s.human 0.169
s.mouse 0.406
p.human 0.00256
p.mouse 4.47e-13




Top 20 genes
Gene human mouse
HSPA1A 4887 5277.5
GTF2F1 4999 4919.0
NUP98 4235 5066.0
GTF2F2 4067 5069.0
POLR2A 3861 5046.0
HSP90AA1 3656 5261.0
KPNA2 5007 3593.0
NUP54 4508 3831.0
NUP205 4438 3588.0
RPL22L1 3380 4103.0
KPNB1 3619 3517.0
RAE1 4471 2389.0
NUP43 4562 2216.0
NUP107 3232 2949.0
FAU 2272 4115.0
NUP188 2117 3830.0
CALR 1534 4995.0
IPO5 1982 3806.0
NUP153 4762 1533.0
KPNA4 1501 4518.0

Click HERE to show all gene set members

All member genes
human mouse
AAAS -3476 1550.0
CALR 1534 4995.0
CANX -836 4736.0
CLTA 1218 1668.0
CLTC 2268 -2802.0
CPSF4 862 4036.0
DNAJC3 1950 1334.0
EIF2AK2 -486 -749.0
FAU 2272 4115.0
GRSF1 -3131 -4623.0
GTF2F1 4999 4919.0
GTF2F2 4067 5069.0
HSP90AA1 3656 5261.0
HSPA1A 4887 5277.5
IPO5 1982 3806.0
ISG15 -3928 1737.0
KPNA1 1833 3439.0
KPNA2 5007 3593.0
KPNA3 -2337 -1621.0
KPNA4 1501 4518.0
KPNB1 3619 3517.0
NDC1 1273 -2350.0
NUP107 3232 2949.0
NUP133 889 -4048.0
NUP153 4762 1533.0
NUP155 4306 -2233.0
NUP160 3998 1035.0
NUP188 2117 3830.0
NUP205 4438 3588.0
NUP214 3124 665.0
NUP35 4571 649.0
NUP37 -327 192.0
NUP43 4562 2216.0
NUP54 4508 3831.0
NUP85 3181 -393.0
NUP88 1244 2212.0
NUP93 -1503 3903.0
NUP98 4235 5066.0
PARP1 -2423 -2631.0
POLR2A 3861 5046.0
POLR2B 4509 -4119.0
POLR2C 4529 -904.0
POLR2D 1669 2692.0
POLR2E -667 1599.0
POLR2G 89 5112.0
POLR2H -3927 3497.0
POLR2I -154 81.0
POLR2K 2480 -1584.0
POLR2L -4314 4110.0
RAE1 4471 2389.0
RAN 2329 1938.0
RANBP2 4470 -3848.0
RPL10 -3902 3841.0
RPL11 -2249 2690.0
RPL14 433 1505.0
RPL18 -1782 3926.0
RPL18A -2969 1546.0
RPL19 -502 2402.0
RPL22 1231 -695.0
RPL22L1 3380 4103.0
RPL23 -115 2472.0
RPL26 1047 3247.0
RPL28 -391 2871.0
RPL3 -786 4892.0
RPL30 286 2070.0
RPL31 -595 4273.0
RPL32 -367 2766.0
RPL34 1447 1856.0
RPL35A 812 1955.0
RPL36A 1261 2266.0
RPL37 -715 2388.0
RPL37A -1043 2280.0
RPL38 231 3306.0
RPL3L -5212 -3395.0
RPL4 -522 1026.0
RPL5 1206 4486.0
RPL7 1440 1916.0
RPL8 -2775 2474.0
RPLP2 -2469 2383.0
RPS11 -1582 3395.0
RPS12 -318 3958.0
RPS13 1131 3118.0
RPS14 -1412 1322.0
RPS15 -1799 1989.0
RPS15A -704 2410.0
RPS16 -1828 3864.0
RPS18 -974 2916.0
RPS19 -2045 2954.0
RPS20 -1844 4785.0
RPS21 -1536 707.0
RPS23 -68 1922.0
RPS24 256 1742.0
RPS26 -282 2982.0
RPS27A 783 1840.0
RPS27L -616 298.0
RPS29 -1140 2499.0
RPS3 -544 3102.0
RPS4X 83 1892.0
RPS5 -1577 2419.0
RPS6 -245 3549.0
RPS8 -1593 2271.0
RPS9 -1107 1580.0
SEC13 730 1702.0
SEH1L 1085 4263.0
TGFB1 -3111 4943.0
TPR 2984 -1026.0
XPO1 990 1809.0



Extracellular matrix organization

Extracellular matrix organization
metric value
setSize 194
pMANOVA 1.08e-12
p.adjustMANOVA 5.56e-11
s.dist 0.287
s.human -0.253
s.mouse 0.134
p.human 1.41e-09
p.mouse 0.00131




Top 20 genes
Gene human mouse
ITGA5 -4752 5178
ADAMTS1 -4587 4708
COL27A1 -5084 4016
FURIN -4221 4117
CAPN2 -3411 4931
ADAM15 -3594 4623
ITGA3 -5514 3010
MUSK -3722 4427
NCAM1 -3954 4132
ITGA9 -5247 3076
CAPN6 -4926 3269
TGFB1 -3111 4943
P4HA1 -2952 4888
DAG1 -5236 2687
ADAMTS4 -3160 4284
SERPINH1 -3526 3768
ITGAM -2633 5045
ADAM8 -2592 5107
PLOD3 -4317 3053
EFEMP2 -4537 2898

Click HERE to show all gene set members

All member genes
human mouse
ACTN1 -676 3696
ADAM10 -1509 -1025
ADAM12 652 5067
ADAM15 -3594 4623
ADAM17 2407 2079
ADAM19 -4678 -2717
ADAM8 -2592 5107
ADAM9 345 150
ADAMTS1 -4587 4708
ADAMTS14 -4689 2235
ADAMTS2 -2757 54
ADAMTS4 -3160 4284
ADAMTS5 3535 -597
ADAMTS9 -783 -1149
AGRN -4903 -2954
ASPN 4413 2344
BGN -1474 3919
BMP1 -4975 43
BMP2 -4256 828
BMP4 332 917
BSG -2248 -2113
CAPN1 -5166 -4425
CAPN10 -2183 -2879
CAPN15 -4668 1828
CAPN2 -3411 4931
CAPN3 -4821 -2677
CAPN5 -2631 -278
CAPN6 -4926 3269
CAPN7 -525 -4964
CAPNS1 -1346 1750
CASK 2884 3209
CASP3 423 5016
CAST -753 4871
CD151 -5391 -927
CD44 837 4987
CD47 -2184 2680
COL11A1 2133 -2218
COL11A2 -2851 -4057
COL12A1 1925 518
COL13A1 -2327 -1962
COL14A1 842 1509
COL15A1 -170 1452
COL16A1 -2954 1661
COL18A1 -2902 2703
COL1A1 -1639 7
COL1A2 -1712 -377
COL22A1 -4865 -3285
COL23A1 -4644 -851
COL24A1 -5131 -4803
COL27A1 -5084 4016
COL28A1 2530 -193
COL2A1 3651 -4815
COL3A1 2974 2528
COL4A1 -4755 696
COL4A2 -5035 869
COL4A3 -3831 -4888
COL4A4 -3022 -3981
COL4A5 -4320 -3467
COL5A1 -1557 2362
COL5A2 -3030 3100
COL5A3 -1554 3850
COL6A1 -1945 2037
COL6A2 -1836 2368
COL6A3 -119 2674
COL6A6 -2138 -3974
COL7A1 -3232 -4028
COL8A1 892 4800
COL8A2 -459 -2313
COLGALT1 -3751 -1280
COLGALT2 -4470 -1449
COMP 278 -1014
CRTAP -3864 1852
CTSB -1198 -795
CTSD -4817 -4037
CTSK 2 263
CTSS -339 5084
CTSV 2209 34
DAG1 -5236 2687
DCN -1048 -896
DDR1 -4782 -251
DDR2 -1956 166
DMD -2970 -4510
DST -1750 -4335
EFEMP1 1210 2573
EFEMP2 -4537 2898
ELN -5058 -386
F11R -2302 -673
FBLN1 -1631 1608
FBLN2 -644 3353
FBLN5 1536 -1300
FBN1 645 3643
FGF2 751 -1095
FMOD -329 -1294
FN1 35 4022
FURIN -4221 4117
HSPG2 -5351 -404
HTRA1 -2591 -2451
ICAM1 1056 4172
ICAM2 -1505 -3478
ITGA1 1757 -4136
ITGA10 -1878 -986
ITGA11 -1012 -2718
ITGA3 -5514 3010
ITGA4 -2878 -5141
ITGA5 -4752 5178
ITGA6 -1002 -5301
ITGA7 -4721 2145
ITGA8 4618 94
ITGA9 -5247 3076
ITGAM -2633 5045
ITGAV -819 50
ITGAX -896 3851
ITGB1 956 4614
ITGB2 -107 4993
ITGB3 -488 4915
ITGB5 -2578 -4797
ITGB6 475 -3733
ITGB8 3244 -2434
JAM2 -5328 -5016
JAM3 1283 -3969
LAMA2 -3799 -762
LAMA3 -1011 -4379
LAMA4 746 -122
LAMA5 -5584 -2744
LAMB1 -457 -387
LAMB2 -4894 -3069
LAMB3 -4991 -4622
LAMC1 -3224 2526
LAMC2 1351 5152
LAMC3 -1576 -1556
LOX 4095 3197
LOXL1 -1591 4000
LOXL2 -3057 3031
LOXL3 -1113 1965
LOXL4 560 27
LRP4 -5165 -4878
LTBP1 -67 -1278
LTBP3 -3176 -2552
LTBP4 -1682 2238
LUM -1839 2479
MFAP1 4936 3812
MFAP2 81 428
MFAP3 4062 2862
MFAP4 -759 -331
MFAP5 -121 4533
MMP11 -3283 -395
MMP14 -1691 1635
MMP15 -5152 -5272
MMP17 -2367 5170
MMP19 -168 4854
MMP2 -692 -2003
MUSK -3722 4427
NCAM1 -3954 4132
NCSTN -2504 1262
NID1 -1264 717
NID2 180 -1996
NTN4 -1261 -948
P4HA1 -2952 4888
P4HA2 -3956 2029
P4HB -2525 4048
PCOLCE -621 2144
PCOLCE2 1740 -53
PDGFA -4328 -4456
PDGFB -606 3347
PHYKPL -5050 -3953
PLEC -5473 -1619
PLOD1 -4688 387
PLOD2 3530 4881
PLOD3 -4317 3053
PPIB -430 3504
PRKCA -2938 -2924
PSEN1 2070 2061
PTPRS -4613 -4187
PXDN -1438 -3483
SDC1 -2046 212
SDC2 1756 4483
SDC3 -4619 2809
SDC4 -2393 5153
SERPINE1 -211 5168
SERPINH1 -3526 3768
SH3PXD2A -5069 -3463
SPARC -2672 -571
SPP1 1162 3043
TGFB1 -3111 4943
TGFB2 4602 1861
TGFB3 -5326 -2035
THBS1 762 4431
TIMP1 -1317 5239
TIMP2 -1886 -738
TNC 803 4329
TNXB -65 2509
TRAPPC4 3239 2726
VCAM1 2866 4713
VCAN 1679 4433



Transport of Mature Transcript to Cytoplasm

Transport of Mature Transcript to Cytoplasm
metric value
setSize 69
pMANOVA 1.18e-12
p.adjustMANOVA 5.82e-11
s.dist 0.549
s.human 0.48
s.mouse 0.267
p.human 5.44e-12
p.mouse 0.000128




Top 20 genes
Gene human mouse
ALYREF 5008 5231
NUP98 4235 5066
CDC40 4670 4455
MAGOH 4561 4010
SLU7 4893 3614
NUP54 4508 3831
EIF4A3 4491 3824
NUP205 4438 3588
SRSF7 3545 4305
FYTTD1 3374 4203
U2AF2 4337 3060
SLBP 2666 4952
SRSF9 3543 3246
EIF4E 2892 3735
RAE1 4471 2389
NUP43 4562 2216
DDX39A 3417 2816
NUP107 3232 2949
SRSF3 2586 3185
NUP188 2117 3830

Click HERE to show all gene set members

All member genes
human mouse
AAAS -3476 1550
ALYREF 5008 5231
CASC3 9 1880
CDC40 4670 4455
CHTOP -574 2867
CPSF1 -3670 1693
CPSF2 -922 1961
CPSF3 1953 -1
CPSF4 862 4036
DDX39A 3417 2816
DDX39B 984 2712
DHX38 2857 -865
EIF4A3 4491 3824
EIF4E 2892 3735
FIP1L1 3587 1848
FYTTD1 3374 4203
GLE1 586 -4722
MAGOH 4561 4010
MAGOHB 2239 2185
NCBP1 -1736 4182
NCBP2 4188 264
NDC1 1273 -2350
NUP107 3232 2949
NUP133 889 -4048
NUP153 4762 1533
NUP155 4306 -2233
NUP160 3998 1035
NUP188 2117 3830
NUP205 4438 3588
NUP214 3124 665
NUP35 4571 649
NUP37 -327 192
NUP43 4562 2216
NUP54 4508 3831
NUP85 3181 -393
NUP88 1244 2212
NUP93 -1503 3903
NUP98 4235 5066
NXF1 4992 -57
NXT1 1765 3801
POLDIP3 -1320 4692
RAE1 4471 2389
RANBP2 4470 -3848
RNPS1 681 -379
SARNP 569 48
SEC13 730 1702
SEH1L 1085 4263
SLBP 2666 4952
SLU7 4893 3614
SRRM1 2285 -746
SRSF1 1871 -429
SRSF11 3911 -4703
SRSF3 2586 3185
SRSF4 1929 4093
SRSF5 1997 -2886
SRSF6 1798 3296
SRSF7 3545 4305
SRSF9 3543 3246
SYMPK -3207 -2811
THOC1 2868 2547
THOC2 4510 -4472
THOC3 2831 -1702
THOC5 4842 542
THOC6 -904 3700
THOC7 -873 -3339
TPR 2984 -1026
U2AF2 4337 3060
UPF3B 1586 -4316
WDR33 3143 1005



Transport of Mature mRNA derived from an Intron-Containing Transcript

Transport of Mature mRNA derived from an Intron-Containing Transcript
metric value
setSize 60
pMANOVA 2.2e-12
p.adjustMANOVA 1.04e-10
s.dist 0.579
s.human 0.52
s.mouse 0.254
p.human 3.24e-12
p.mouse 0.000683




Top 20 genes
Gene human mouse
ALYREF 5008 5231
NUP98 4235 5066
CDC40 4670 4455
MAGOH 4561 4010
SLU7 4893 3614
NUP54 4508 3831
EIF4A3 4491 3824
NUP205 4438 3588
SRSF7 3545 4305
FYTTD1 3374 4203
U2AF2 4337 3060
SRSF9 3543 3246
RAE1 4471 2389
NUP43 4562 2216
DDX39A 3417 2816
NUP107 3232 2949
SRSF3 2586 3185
NUP188 2117 3830
SRSF4 1929 4093
THOC1 2868 2547

Click HERE to show all gene set members

All member genes
human mouse
AAAS -3476 1550
ALYREF 5008 5231
CASC3 9 1880
CDC40 4670 4455
CHTOP -574 2867
DDX39A 3417 2816
DDX39B 984 2712
DHX38 2857 -865
EIF4A3 4491 3824
FYTTD1 3374 4203
GLE1 586 -4722
MAGOH 4561 4010
MAGOHB 2239 2185
NCBP1 -1736 4182
NCBP2 4188 264
NDC1 1273 -2350
NUP107 3232 2949
NUP133 889 -4048
NUP153 4762 1533
NUP155 4306 -2233
NUP160 3998 1035
NUP188 2117 3830
NUP205 4438 3588
NUP214 3124 665
NUP35 4571 649
NUP37 -327 192
NUP43 4562 2216
NUP54 4508 3831
NUP85 3181 -393
NUP88 1244 2212
NUP93 -1503 3903
NUP98 4235 5066
NXF1 4992 -57
NXT1 1765 3801
POLDIP3 -1320 4692
RAE1 4471 2389
RANBP2 4470 -3848
RNPS1 681 -379
SARNP 569 48
SEC13 730 1702
SEH1L 1085 4263
SLU7 4893 3614
SRRM1 2285 -746
SRSF1 1871 -429
SRSF11 3911 -4703
SRSF3 2586 3185
SRSF4 1929 4093
SRSF5 1997 -2886
SRSF6 1798 3296
SRSF7 3545 4305
SRSF9 3543 3246
THOC1 2868 2547
THOC2 4510 -4472
THOC3 2831 -1702
THOC5 4842 542
THOC6 -904 3700
THOC7 -873 -3339
TPR 2984 -1026
U2AF2 4337 3060
UPF3B 1586 -4316



Cell Cycle, Mitotic

Cell Cycle, Mitotic
metric value
setSize 397
pMANOVA 2.27e-12
p.adjustMANOVA 1.04e-10
s.dist 0.233
s.human 0.182
s.mouse 0.144
p.human 6.23e-10
p.mouse 9.94e-07




Top 20 genes
Gene human mouse
PPME1 4727 5198
NUP98 4235 5066
CCNE1 4388 4753
TOP2A 4691 4445
CEP152 4492 4513
RAD21 4417 4508
FBXW11 4385 4535
MYC 3994 4886
PPP2R5A 4590 4219
HSP90AA1 3656 5261
UBE2S 4441 4268
DBF4 4260 4331
SKP2 4205 4385
NUP54 4508 3831
EML4 4736 3589
MCM6 3462 4822
RAB1A 3634 4583
FKBPL 4474 3673
TNPO1 3184 5129
BORA 4768 3401

Click HERE to show all gene set members

All member genes
human mouse
AAAS -3476 1550.0
ABL1 -4533 -3545.0
ACTR1A -4126 1651.0
AHCTF1 4662 -1792.0
AJUBA -4112 -892.0
AKAP9 -573 -5181.0
AKT1 -4954 342.0
AKT2 -4057 -4450.0
AKT3 1343 -320.0
ALMS1 4347 1162.0
ANAPC1 572 -4087.0
ANAPC10 1974 2134.0
ANAPC11 -3265 -1751.0
ANAPC15 -3393 1787.0
ANAPC16 -3612 -1148.0
ANAPC2 -2185 -3532.0
ANAPC4 -720 -4834.0
ANAPC5 1284 -2104.0
ANAPC7 1595 2349.0
ANKLE2 1499 855.0
ARPP19 2927 4020.0
AURKA 3811 325.0
B9D2 1676 -553.0
BANF1 -2281 674.0
BLZF1 4266 115.0
BORA 4768 3401.0
BTRC -1187 -2758.0
BUB3 4201 1662.0
CABLES1 -4484 459.0
CC2D1B 1025 39.0
CCNA2 3061 4292.0
CCND1 757 529.0
CCND2 225 405.0
CCND3 786 1371.0
CCNE1 4388 4753.0
CCNE2 4667 147.0
CCNH 3825 -1657.0
CCP110 4605 -630.0
CDC14A 957 -3217.0
CDC16 86 -1984.0
CDC23 3850 -1171.0
CDC25A 4090 2308.0
CDC25B 4652 2780.0
CDC26 2750 2457.0
CDC27 665 1230.0
CDC7 2421 2065.0
CDK1 1580 3263.0
CDK11A 167 -180.5
CDK11B 1690 -180.5
CDK2 849 2686.0
CDK4 703 3417.0
CDK5RAP2 -3037 -1178.0
CDK6 1090 3036.0
CDK7 1571 -2032.0
CDKN1A -4927 5092.0
CDKN1B -3284 -2450.0
CDKN1C -5394 -4228.0
CDKN2B -2827 2812.0
CDKN2C 3612 3091.0
CDKN2D 142 -1212.0
CENPC 3555 -2660.0
CENPJ 1720 -467.0
CENPL 3768 2470.0
CENPO 1005 440.0
CENPQ 1344 5001.0
CENPT -2196 3930.0
CEP135 1891 -1400.0
CEP152 4492 4513.0
CEP164 3699 1799.0
CEP192 2073 -303.0
CEP250 3192 -3961.0
CEP290 3352 -4522.0
CEP41 4357 1396.0
CEP57 611 -1027.0
CEP63 -2491 -663.0
CEP70 -3094 -96.0
CEP76 3163 2269.0
CEP78 3895 -777.0
CETN2 -587 -2273.0
CHMP2A 1155 2310.0
CHMP2B 967 -4167.0
CHMP3 -3919 1578.0
CHMP4B -1125 329.0
CHMP6 -4368 279.0
CHMP7 1743 -3701.0
CKAP5 -3973 -1370.0
CKS1B 1446 4555.0
CLASP1 -3713 1181.0
CLASP2 2507 -309.0
CLIP1 418 -4689.0
CNEP1R1 1729 -2101.0
CNTRL 4333 -5162.0
CSNK1D -3539 3832.0
CSNK1E -5045 816.0
CSNK2A1 1796 -1733.0
CSNK2A2 2123 1393.0
CSNK2B 1917 -296.0
CTDNEP1 -2509 -1879.0
CUL1 -3121 -1536.0
DBF4 4260 4331.0
DCTN1 -347 -2402.0
DCTN2 -3157 -448.0
DCTN3 -943 2888.0
DHFR -3638 1542.5
DNA2 37 2385.0
DSN1 2075 534.0
DYNC1H1 -1442 -2348.0
DYNC1I2 2591 -2971.0
DYNC1LI1 2883 1316.0
DYNC1LI2 1750 -1620.0
DYNLL1 -1331 4245.0
DYRK1A -2401 2200.0
E2F1 -529 4663.0
E2F3 -4683 -1694.0
E2F4 -439 5017.0
E2F5 -249 2797.0
E2F6 650 -3768.0
EMD -651 3538.0
EML4 4736 3589.0
ENSA -114 -1834.0
EP300 3403 -1622.0
ESCO1 680 -2410.0
ESPL1 408 4211.0
FBXL18 1610 -2831.0
FBXW11 4385 4535.0
FEN1 4094 3551.0
FKBPL 4474 3673.0
FZR1 -1244 3620.0
GINS1 441 1703.0
GINS3 -1006 2295.0
GINS4 -1475 -1046.0
GMNN 4714 -3905.0
GOLGA2 919 -3262.0
GORASP1 -4615 -2387.0
GORASP2 2697 3743.0
GSK3B 897 3200.0
H2AFX 2356 5062.0
HAUS1 1263 722.0
HAUS2 2905 109.0
HAUS3 3748 4141.0
HAUS4 -2191 -1774.0
HAUS6 3590 -1282.0
HAUS8 758 3915.0
HDAC8 209 -3381.0
HSP90AA1 3656 5261.0
HSP90AB1 -639 4629.0
INCENP 3676 3359.0
IST1 3827 4131.0
ITGB3BP 1048 -2448.0
JAK2 -2569 -5057.0
KIF18A 3832 4144.0
KIF23 1216 4134.0
KIF2A -4390 4818.0
KPNB1 3619 3517.0
LBR 2244 -1398.0
LCMT1 729 -996.0
LEMD2 -1073 679.0
LEMD3 3330 1458.0
LIG1 -3127 3257.0
LIN37 -1988 4591.0
LIN52 915 -4751.0
LIN54 4080 -2234.0
LIN9 1166 -4383.0
LMNA -4692 5155.0
LMNB1 3392 2947.0
LPIN1 -2877 -4196.0
LPIN2 3569 2728.0
LPIN3 -1052 61.0
LYN 785 3984.0
MAD1L1 -3382 2990.0
MAD2L1 1101 3554.0
MAPK1 1988 -648.0
MAPK3 -1024 3725.0
MAPRE1 3454 4528.0
MAU2 -3188 -2899.0
MAX -2352 1069.0
MCM2 -3977 2851.0
MCM3 600 4761.0
MCM4 -610 4841.0
MCM5 -1490 4861.0
MCM6 3462 4822.0
MCM7 2515 2881.0
MCM8 -3355 -3274.0
MCPH1 2176 -1854.0
MIS12 2400 4069.0
MNAT1 830 -2433.0
MYC 3994 4886.0
MZT1 3517 -4547.0
MZT2A -3883 -2023.5
MZT2B -3442 -2023.5
NCAPD2 4017 -3000.0
NCAPD3 3002 -4897.0
NCAPG2 -13 1154.0
NCAPH 1129 3314.0
NCAPH2 -1845 -2829.0
NDC1 1273 -2350.0
NDE1 4322 -2784.0
NDEL1 4631 1071.0
NEDD1 1034 -933.0
NEK6 -5042 2173.0
NEK7 535 -2342.0
NEK9 -2856 -2338.0
NIPBL 4675 -4955.0
NME7 2020 -685.0
NUDC 3212 2586.0
NUMA1 -4395 -1953.0
NUP107 3232 2949.0
NUP133 889 -4048.0
NUP153 4762 1533.0
NUP155 4306 -2233.0
NUP160 3998 1035.0
NUP188 2117 3830.0
NUP205 4438 3588.0
NUP214 3124 665.0
NUP35 4571 649.0
NUP37 -327 192.0
NUP43 4562 2216.0
NUP54 4508 3831.0
NUP85 3181 -393.0
NUP88 1244 2212.0
NUP93 -1503 3903.0
NUP98 4235 5066.0
ODF2 1954 -1185.0
OFD1 811 -3024.0
OPTN 1980 -1925.0
ORC2 1022 4505.0
ORC3 -1627 -3964.0
ORC4 3929 1594.0
ORC5 4429 -566.0
ORC6 2184 -425.0
PAFAH1B1 -2026 -2663.0
PCM1 1788 -4915.0
PCNA 1329 5082.0
PCNT -1269 -5149.0
PDS5A 1248 -2950.0
PDS5B -3191 -5111.0
PHF8 3393 2137.0
PHLDA1 -3126 5180.0
PLK4 3581 2306.0
POLA1 1944 1826.0
POLA2 -173 -1993.0
POLD1 -3218 580.0
POLD2 -4806 1491.0
POLD3 3486 1097.0
POLD4 -2084 3728.0
POLE -3659 436.0
POLE2 1264 3777.0
POLE3 4335 -269.0
POLE4 409 3529.0
PPME1 4727 5198.0
PPP1CB -1374 -4149.0
PPP1CC 4081 399.0
PPP1R12A 4131 2449.0
PPP1R12B -5005 -1873.0
PPP2CA 4482 3008.0
PPP2CB 2458 4129.0
PPP2R1A -4013 -696.0
PPP2R1B 3028 4619.0
PPP2R2A 2264 3799.0
PPP2R2D -2153 2506.0
PPP2R5A 4590 4219.0
PPP2R5B -1524 121.0
PPP2R5C -2508 -3684.0
PPP2R5D -3449 -2058.0
PPP2R5E 4644 1539.0
PRIM1 311 3722.0
PRIM2 3544 4441.0
PRKACA -4691 -1606.0
PRKAR2B 3460 2616.0
PRKCA -2938 -2924.0
PSMA1 2820 3328.0
PSMA3 3434 -4.0
PSMA4 769 958.0
PSMA6 2199 -1044.0
PSMA7 -2980 976.0
PSMB1 954 2628.0
PSMB10 -1800 2907.0
PSMB2 618 2471.0
PSMB4 -235 2096.0
PSMB5 -4113 -606.0
PSMB6 -793 914.0
PSMB7 -831 -1453.0
PSMB8 -675 2066.0
PSMB9 -1611 -2973.0
PSMC1 449 -336.0
PSMC2 -1311 3241.0
PSMC3 -2439 -369.0
PSMC4 2724 1416.0
PSMC5 1212 -1123.0
PSMC6 -2520 3423.0
PSMD1 2619 -1191.0
PSMD10 -1227 525.0
PSMD11 995 5183.0
PSMD12 3831 536.0
PSMD13 821 1665.0
PSMD14 -635 3816.0
PSMD2 -713 -555.0
PSMD3 -3343 2226.0
PSMD4 -214 2558.0
PSMD5 1807 3558.0
PSMD6 3537 -2207.0
PSMD7 -2329 1233.0
PSMD8 -3171 4626.0
PSMD9 4204 -970.0
PSME1 -2771 3350.0
PSME2 -4085 3584.0
PSME3 3333 3379.0
PSME4 1960 -4574.0
PSMF1 683 -1480.0
PTTG1 4843 -2819.0
RAB1A 3634 4583.0
RAB1B -2997 67.0
RAB2A 1999 -249.0
RAB8A 3378 2789.0
RAD21 4417 4508.0
RAE1 4471 2389.0
RAN 2329 1938.0
RANBP2 4470 -3848.0
RANGAP1 483 4340.0
RB1 -2449 1464.0
RBBP4 1072 2469.0
RBL1 -1617 778.0
RBL2 -242 -5105.0
RBX1 -733 -968.0
RCC1 997 3619.0
RCC2 4178 3436.0
RFC1 4641 1093.0
RFC2 622 -1170.0
RFC3 2151 4113.0
RFC4 3542 964.0
RFC5 1409 3528.0
RPA1 -1837 -4231.0
RPA2 2889 -1373.0
RPA3 2702 -1706.0
RPS27A 783 1840.0
SDCCAG8 1021 3590.0
SEC13 730 1702.0
SEH1L 1085 4263.0
SET 3683 2131.0
SFI1 -1212 -2485.0
SIRT2 -4852 -11.0
SKA2 2399 907.0
SKP1 2028 -2504.0
SKP2 4205 4385.0
SMC1A 3824 -810.0
SMC2 2477 3769.0
SMC3 4878 2878.0
SMC4 4127 1098.0
SPAST 3456 -3172.0
SRC -3910 1378.0
SSNA1 -2879 -732.0
STAG1 4246 -1940.0
STAG2 31 -4179.0
SUMO1 4213 1399.0
TAOK1 1644 -3805.0
TFDP1 -2245 -2659.0
TFDP2 4029 -5361.0
TK1 -3225 906.0
TMPO 4574 335.0
TNPO1 3184 5129.0
TOP2A 4691 4445.0
TP53 575 3751.0
TPR 2984 -1026.0
TPX2 3446 2359.0
TUBA1A -5228 3715.0
TUBA1B -5324 4914.0
TUBA1C -4883 5125.0
TUBA4A -5342 2072.0
TUBA8 -1116 -888.0
TUBB -3118 5070.0
TUBB2A -4676 4448.0
TUBB2B -4704 4960.0
TUBB4B 430 4896.0
TUBB6 -5060 5204.0
TUBG1 -3728 328.0
TUBG2 93 -164.0
TUBGCP2 -3362 -2965.0
TUBGCP3 2352 1674.0
TUBGCP4 4074 1827.0
TUBGCP6 -3953 -3026.0
TYMS -2042 2614.0
UBC 2672 4480.0
UBE2C 4949 463.0
UBE2D1 -1588 -4032.0
UBE2E1 -1132 -479.0
UBE2I 1246 1214.0
UBE2S 4441 4268.0
USO1 -738 1516.0
VPS4A -1545 -2086.0
VRK1 1696 -959.0
VRK2 1461 -2309.0
WEE1 -4561 1755.0
XPO1 990 1809.0
YWHAE 1394 -914.0
YWHAG -2372 -3104.0
ZW10 1474 1263.0
ZWINT 2778 5161.0



RNA Polymerase II Pre-transcription Events

RNA Polymerase II Pre-transcription Events
metric value
setSize 69
pMANOVA 6.37e-12
p.adjustMANOVA 2.8e-10
s.dist 0.538
s.human 0.432
s.mouse 0.32
p.human 5.54e-10
p.mouse 4.29e-06




Top 20 genes
Gene human mouse
TAF4B 4967 5209
CTR9 4954 5042
GTF2F1 4999 4919
TAF7 4717 4909
SUPT6H 4807 4811
GTF2B 4276 5124
EAF1 4531 4808
GTF2A1 4730 4588
GTF2F2 4067 5069
POLR2A 3861 5046
TAF3 4294 4474
SUPT16H 3885 4363
TAF2 4591 3381
TAF5 4309 2830
MLLT3 3202 3787
TAF12 3100 3164
CTDP1 2071 4335
TAF13 4749 1567
SSRP1 1755 3948
AFF4 3610 1865

Click HERE to show all gene set members

All member genes
human mouse
AFF4 3610 1865.0
CCNH 3825 -1657.0
CCNK 3139 154.0
CCNT1 4896 -1160.0
CCNT2 4381 -5015.0
CDC73 2659 -1467.0
CDK7 1571 -2032.0
CDK9 -1348 4462.0
CTDP1 2071 4335.0
CTR9 4954 5042.0
EAF1 4531 4808.0
ELL -3990 3019.0
ERCC2 824 2393.0
ERCC3 473 1570.0
GTF2A1 4730 4588.0
GTF2A2 4648 -1742.0
GTF2B 4276 5124.0
GTF2E1 2188 1803.0
GTF2E2 2041 120.0
GTF2F1 4999 4919.0
GTF2F2 4067 5069.0
GTF2H1 3886 1058.0
GTF2H2 4419 -2446.5
GTF2H3 -1925 467.0
GTF2H5 -878 -1711.0
IWS1 2510 1707.0
LEO1 2784 2307.0
MLLT1 472 1878.0
MLLT3 3202 3787.0
MNAT1 830 -2433.0
NCBP1 -1736 4182.0
NCBP2 4188 264.0
NELFA 356 3929.0
NELFB -1196 2773.0
NELFCD 1896 -2294.0
NELFE -2178 3334.0
PAF1 2516 -2180.0
POLR2A 3861 5046.0
POLR2B 4509 -4119.0
POLR2C 4529 -904.0
POLR2D 1669 2692.0
POLR2E -667 1599.0
POLR2G 89 5112.0
POLR2H -3927 3497.0
POLR2I -154 81.0
POLR2K 2480 -1584.0
POLR2L -4314 4110.0
RTF1 -2993 -2893.0
SSRP1 1755 3948.0
SUPT16H 3885 4363.0
SUPT4H1 3648 -1203.0
SUPT5H 1321 3508.0
SUPT6H 4807 4811.0
TAF1 1708 -350.0
TAF10 -273 2957.0
TAF11 2962 -484.0
TAF12 3100 3164.0
TAF13 4749 1567.0
TAF2 4591 3381.0
TAF3 4294 4474.0
TAF4 -1340 3063.0
TAF4B 4967 5209.0
TAF5 4309 2830.0
TAF6 -912 55.0
TAF7 4717 4909.0
TAF9B 1874 519.0
TBP 1137 2611.0
TCEA1 4037 647.0
WDR61 -1148 301.0



RNA Polymerase II Transcription

RNA Polymerase II Transcription
metric value
setSize 889
pMANOVA 6.76e-12
p.adjustMANOVA 2.87e-10
s.dist 0.153
s.human 0.138
s.mouse 0.0665
p.human 8.38e-12
p.mouse 0.001




Top 20 genes
Gene human mouse
ALYREF 5008 5231
TAF4B 4967 5209
CTR9 4954 5042
GTF2F1 4999 4919
CLP1 4787 5127
TAF7 4717 4909
SUPT6H 4807 4811
ELL2 4753 4829
RYBP 4895 4575
EZH2 4698 4740
SIRT1 4935 4484
GTF2B 4276 5124
EAF1 4531 4808
GTF2A1 4730 4588
ZKSCAN5 4612 4688
NFYA 4965 4269
CDK12 4852 4326
CCNE1 4388 4753
CDC40 4670 4455
PLK2 4764 4365

Click HERE to show all gene set members

All member genes
human mouse
ABCA6 -135 -3028.0
ABL1 -4533 -3545.0
ACTL6A 4077 3325.0
AFF4 3610 1865.0
AGO1 2453 -2704.0
AGO2 -4001 -1788.0
AGO3 2529 -3975.0
AGO4 -3006 -3323.0
AIFM2 -4217 -2578.0
AKT1 -4954 342.0
AKT2 -4057 -4450.0
AKT3 1343 -320.0
ALYREF 5008 5231.0
ANAPC1 572 -4087.0
ANAPC10 1974 2134.0
ANAPC11 -3265 -1751.0
ANAPC15 -3393 1787.0
ANAPC16 -3612 -1148.0
ANAPC2 -2185 -3532.0
ANAPC4 -720 -4834.0
ANAPC5 1284 -2104.0
ANAPC7 1595 2349.0
APAF1 -3469 2921.0
APOE -1428 -89.0
AR -4468 -5288.0
ARID1A -1226 3491.0
ARID1B -3838 2336.0
ARID2 2812 -1805.0
ARID3A -4418 1310.0
ASH2L -45 -3813.0
ASUN 1039 2317.0
ATAD2 4225 1685.0
ATF2 3130 1863.0
ATM 1449 -5067.0
ATP1B4 -5072 4958.0
ATR 1983 -63.0
ATXN3 4003 1472.0
AURKA 3811 325.0
AUTS2 -4742 3324.0
AXIN1 -730 3618.0
BANP 2381 3194.0
BAX -1846 4438.0
BCL2L11 -4974 2480.0
BCL6 -5018 -4816.0
BDNF 1086 5114.0
BID -4951 3840.0
BLM 1103 4695.0
BMI1 3349 2265.0
BMP2 -4256 828.0
BNIP3L 3835 -1911.0
BRD1 -2076 508.0
BRD2 4330 3261.0
BRD7 221 -4649.0
BRPF1 3074 3878.0
BRPF3 3668 4189.0
BTG1 3137 4645.0
BTG2 -5444 5224.0
CALM1 -4464 96.0
CAMK2A -5527 -4430.0
CAMK2B -5497 -4230.0
CAMK2D -2223 4137.0
CAMK2G -2097 -4962.0
CARM1 -4331 -4868.0
CASC3 9 1880.0
CASP1 -1298 3173.0
CASP2 2946 -3849.0
CASP6 4829 -2418.0
CAT -4828 -4266.0
CAV1 -646 -652.0
CBFB 3786 -4544.0
CBX2 2360 -1671.0
CBX4 3208 4863.0
CBX5 1538 -4637.0
CBX6 -482 912.0
CBX8 -917 -541.0
CCNA2 3061 4292.0
CCNC 4650 3537.0
CCND1 757 529.0
CCND2 225 405.0
CCND3 786 1371.0
CCNE1 4388 4753.0
CCNE2 4667 147.0
CCNG1 1596 -2074.0
CCNG2 -2635 -3814.0
CCNH 3825 -1657.0
CCNK 3139 154.0
CCNT1 4896 -1160.0
CCNT2 4381 -5015.0
CDC16 86 -1984.0
CDC23 3850 -1171.0
CDC26 2750 2457.0
CDC27 665 1230.0
CDC40 4670 4455.0
CDC7 2421 2065.0
CDC73 2659 -1467.0
CDK1 1580 3263.0
CDK12 4852 4326.0
CDK13 4123 1830.0
CDK2 849 2686.0
CDK4 703 3417.0
CDK5 -1007 -793.0
CDK6 1090 3036.0
CDK7 1571 -2032.0
CDK8 623 -1722.0
CDK9 -1348 4462.0
CDKN1A -4927 5092.0
CDKN1B -3284 -2450.0
CDKN2B -2827 2812.0
CEBPB -4699 1850.0
CENPJ 1720 -467.0
CHD3 -3721 -4142.0
CHD4 -4283 464.0
CHEK2 1311 1076.0
CHM 1406 -3917.0
CHTOP -574 2867.0
CITED2 770 5188.0
CITED4 -4657 -4817.0
CLDN5 -2058 2154.0
CLP1 4787 5127.0
CNOT1 4456 -3764.0
CNOT10 1314 -2770.0
CNOT11 2698 -468.0
CNOT2 3263 1266.0
CNOT3 857 3443.0
CNOT4 2350 2040.0
CNOT6 1509 2491.0
CNOT6L -2201 -298.0
CNOT7 1298 -926.0
CNOT8 3240 -1672.0
COL1A1 -1639 7.0
COX11 -2860 -1166.0
COX14 -2772 -4368.0
COX16 -2259 -1943.0
COX18 -554 635.0
COX19 3053 3493.0
COX20 1104 -2275.0
COX4I1 -2357 -1289.0
COX5A -2511 -2550.0
COX5B -2559 458.0
COX6A1 2259 2241.0
COX6B1 -2231 -855.0
COX6C -18 -845.0
COX7B 144 -729.0
COX7C -1495 -176.0
COX8A -4337 2642.0
CPSF1 -3670 1693.0
CPSF2 -922 1961.0
CPSF3 1953 -1.0
CPSF3L -1923 1572.0
CPSF4 862 4036.0
CPSF7 407 2081.0
CRADD -2847 -4600.0
CREB1 2179 -4329.0
CREBBP 1506 3139.0
CSNK2A1 1796 -1733.0
CSNK2A2 2123 1393.0
CSNK2B 1917 -296.0
CSTF1 2216 2463.0
CSTF2 1437 -2189.0
CSTF2T 2703 4265.0
CSTF3 -2793 4044.0
CTDP1 2071 4335.0
CTGF -275 4426.0
CTNNB1 1714 -780.0
CTR9 4954 5042.0
CTSK 2 263.0
CTSV 2209 34.0
CUL1 -3121 -1536.0
DAXX 4449 4197.0
DDB2 -5027 -3332.0
DDIT3 -1718 243.0
DDIT4 -2764 4792.0
DDX39A 3417 2816.0
DDX39B 984 2712.0
DEK 2056 4641.0
DGCR8 -4643 -12.0
DHX38 2857 -865.0
DLL1 -3980 -4227.0
DNA2 37 2385.0
DPY30 3923 275.0
DYRK2 -2000 -3920.0
E2F1 -529 4663.0
E2F4 -439 5017.0
E2F5 -249 2797.0
E2F6 650 -3768.0
E2F7 512 3338.0
E2F8 -5620 5126.0
EAF1 4531 4808.0
EED 3304 3671.0
EGFR 424 1475.0
EHMT1 -76 -2601.0
EHMT2 -520 -260.0
EIF4A3 4491 3824.0
ELF1 4399 3868.0
ELF2 -2817 -2798.0
ELL -3990 3019.0
ELL2 4753 4829.0
EP300 3403 -1622.0
EPC1 362 4066.0
ERBB2 -5511 673.0
ERCC2 824 2393.0
ERCC3 473 1570.0
ESR1 -1770 -3364.0
ESRRA -4570 -4245.0
ESRRB -2671 4031.0
ESRRG -4340 -4719.0
EZH2 4698 4740.0
FANCC -709 -459.0
FAS -4771 2899.0
FBXO32 -4380 -4921.0
FBXW7 -886 -330.0
FIP1L1 3587 1848.0
FKBP5 750 553.0
FOS 1865 5273.0
FOXO1 -432 1302.0
FOXO3 -42 -1131.0
FOXO4 -3493 -4492.0
FOXO6 -4157 -4011.0
FYTTD1 3374 4203.0
FZR1 -1244 3620.0
G6PD 579 4742.0
GADD45A 514 -1267.0
GAMT -5400 -5019.0
GATAD2A -975 4779.0
GATAD2B 304 3259.0
GLI2 -1180 3498.0
GLI3 3731 101.0
GLS 4937 -244.0
GPAM 1132 -5246.0
GPI -5210 -4132.0
GPS2 2002 3298.0
GSK3B 897 3200.0
GSR -2148 1119.0
GTF2A1 4730 4588.0
GTF2A2 4648 -1742.0
GTF2B 4276 5124.0
GTF2E1 2188 1803.0
GTF2E2 2041 120.0
GTF2F1 4999 4919.0
GTF2F2 4067 5069.0
GTF2H1 3886 1058.0
GTF2H2 4419 -2446.5
GTF2H3 -1925 467.0
GTF2H5 -878 -1711.0
H2AFX 2356 5062.0
HDAC10 -3116 -2283.0
HDAC11 -4482 3956.0
HDAC2 4386 -1101.0
HDAC3 -178 -4320.0
HDAC4 -5061 -4325.0
HDAC5 -4921 2376.0
HDAC6 -4164 3925.0
HDAC7 -3827 -2596.0
HDAC8 209 -3381.0
HDAC9 -3759 2762.0
HES1 1695 -1766.0
HEY1 4826 451.0
HIPK1 4147 3646.0
HIPK2 -4312 -2060.0
HIVEP3 -179 4383.0
HSPD1 -855 -708.0
HTT -70 4380.0
HUS1 2435 -4471.0
IGFBP3 2922 -4847.0
ING2 3993 -1954.0
ING5 -2726 3394.0
INTS1 -1418 -2905.0
INTS10 4175 -4934.0
INTS12 3830 4418.0
INTS2 1193 1527.0
INTS3 1102 2904.0
INTS4 1878 1643.0
INTS5 1592 3677.0
INTS6 2200 4768.0
INTS7 2980 -1362.0
INTS8 1194 1805.0
INTS9 1494 4574.0
IRAK1 -4351 -480.0
ITCH 4319 -2959.0
ITGA4 -2878 -5141.0
ITGA5 -4752 5178.0
ITGBL1 1885 -1676.0
IWS1 2510 1707.0
JAG1 3237 -2093.0
JMY 3902 -2949.0
JUN 2469 5225.0
JUNB -2593 5221.0
KAT2A -5053 -1162.0
KAT2B -3340 -5260.0
KAT5 447 3955.0
KAT6A 3849 -725.0
KCTD1 -2989 1161.0
KCTD15 -3871 -4739.0
KCTD6 2748 3456.0
KDM5B 4870 2819.0
KLF4 3126 5024.0
KMT2A 4833 -157.0
KMT2C 4070 -3697.0
KMT2D -1176 -1807.0
KMT2E 3381 548.0
KRAS 3546 4454.0
KRBA1 -948 -5356.0
L3MBTL2 -956 3155.0
LAMTOR1 -800 -2671.0
LAMTOR2 -1715 -424.0
LAMTOR3 3134 3162.0
LAMTOR4 -2977 2289.0
LAMTOR5 636 -324.0
LBR 2244 -1398.0
LDB1 -5369 -2642.0
LEO1 2784 2307.0
LGALS3 1062 4809.0
LIFR -994 -4795.0
LMO2 -1725 2311.0
LRPPRC 1656 -4390.0
LSM10 -3826 1565.0
LSM11 -2895 465.0
MAF -5349 -5312.0
MAGOH 4561 4010.0
MAGOHB 2239 2185.0
MAML1 2770 4603.0
MAML2 2681 640.0
MAML3 -2079 -345.0
MAMLD1 -1668 1073.0
MAP2K6 1456 -4876.0
MAPK1 1988 -648.0
MAPK11 -3385 -333.0
MAPK14 -1562 -1635.0
MAPK3 -1024 3725.0
MAPKAP1 -405 2624.0
MAX -2352 1069.0
MBD3 -3419 1364.0
MDC1 841 2997.0
MDM2 3253 3321.0
MDM4 2051 -4809.0
MEAF6 1066 1292.0
MECP2 -1705 -4130.0
MED1 4772 -2976.0
MED10 4087 2651.0
MED12 -2130 -2791.0
MED13 4601 4442.0
MED14 2781 -4663.0
MED15 1233 4823.0
MED16 -2476 -4328.0
MED17 4255 676.0
MED20 3604 -3993.0
MED23 3909 2513.0
MED24 -4786 -4086.0
MED25 2948 1925.0
MED26 4038 2036.0
MED27 1227 3689.0
MED30 2307 -28.0
MED31 4638 377.0
MED4 4026 4309.0
MED6 4813 2205.0
MED7 4316 2498.0
MED8 4163 -215.0
MEF2C -4610 -2794.0
MEN1 1348 2492.0
MET -3529 2929.0
MGA 4502 -4742.0
MLH1 -1210 -4562.0
MLLT1 472 1878.0
MLLT3 3202 3787.0
MLST8 -3485 -2266.0
MNAT1 830 -2433.0
MOV10 -4127 1367.0
MSH2 4647 -5020.0
MSTN -3974 4425.0
MT-CO1 -3167 -4114.0
MTA2 3682 946.0
MTOR -1191 -1922.0
MYC 3994 4886.0
MYL9 -4777 11.0
NABP1 -3908 5015.0
NABP2 -279 -1673.0
NBN 1286 -1205.0
NCBP1 -1736 4182.0
NCBP2 4188 264.0
NCOR1 2625 -3925.0
NCOR2 -5167 -1521.0
NDRG1 -102 650.0
NDUFA4 -393 -682.0
NEDD4L 4279 -2158.0
NELFA 356 3929.0
NELFB -1196 2773.0
NELFCD 1896 -2294.0
NELFE -2178 3334.0
NFATC2 -3264 3355.0
NFKB1 -4233 3315.0
NFYA 4965 4269.0
NFYB 1632 -3915.0
NFYC -1444 -1181.0
NOC2L 1374 1201.0
NOP2 3472 4824.0
NOTCH1 -5460 44.0
NOTCH3 -1225 773.0
NR1D1 -5185 -985.0
NR1D2 1828 -5211.0
NR1H2 2288 3553.0
NR1H3 -3630 -3237.0
NR2C1 679 -897.0
NR2C2 1579 -4371.0
NR2C2AP 2640 2663.0
NR2F1 -4439 1268.0
NR2F6 -4543 2556.0
NR3C1 985 -4192.0
NR3C2 -1723 -18.0
NR4A1 -5560 -642.0
NR4A2 -1651 4423.0
NR4A3 -4264 4712.0
NR6A1 -2345 2302.0
NRBF2 4966 -2441.0
NRBP1 2753 3576.0
NUAK1 -2765 86.0
NUDT21 3626 3457.0
PAF1 2516 -2180.0
PARP1 -2423 -2631.0
PBRM1 3523 -4706.0
PCBP4 -5523 -1872.0
PCF11 -1597 -2897.0
PCGF5 1470 586.0
PCGF6 1159 2779.0
PCNA 1329 5082.0
PDPK1 3443 2222.0
PERP 831 -2655.0
PHAX 4729 840.0
PHC1 456 -1955.0
PHC2 -3719 4976.0
PHC3 3141 -3012.0
PHF20 819 -2632.0
PIN1 -3515 1213.0
PINK1 -4060 -3052.0
PIP4K2A 4108 4491.0
PIP4K2C 2827 2664.0
PITX2 -5256 -35.0
PLAGL1 -4577 3731.0
PLK2 4764 4365.0
PLK3 -1003 4968.0
PLXNA4 -319 -842.0
PMAIP1 -4203 5154.0
PML 3338 3449.0
PMS2 806 -1784.0
POLDIP3 -1320 4692.0
POLR2A 3861 5046.0
POLR2B 4509 -4119.0
POLR2C 4529 -904.0
POLR2D 1669 2692.0
POLR2E -667 1599.0
POLR2G 89 5112.0
POLR2H -3927 3497.0
POLR2I -154 81.0
POLR2K 2480 -1584.0
POLR2L -4314 4110.0
POU2F1 3019 -3333.0
POU4F1 -1640 -4107.0
PPARA -4997 -4570.0
PPARD -4213 -2337.0
PPARG -1621 -2269.0
PPARGC1A -4212 -5006.0
PPARGC1B -5257 -4147.0
PPM1A 3438 -2366.0
PPM1D 1792 2505.0
PPP1R13B 3413 770.0
PPP1R13L -3554 3890.0
PPP2CA 4482 3008.0
PPP2CB 2458 4129.0
PPP2R1A -4013 -696.0
PPP2R1B 3028 4619.0
PPP2R5C -2508 -3684.0
PRDM1 -50 -4776.0
PRDX1 605 1340.0
PRDX2 -5293 -2557.0
PRDX5 -3356 -1867.0
PRELID1 1651 4804.0
PRKAA1 3389 2810.0
PRKAA2 -3219 -5163.0
PRKAB1 3436 1814.0
PRKAB2 -2332 -2820.0
PRKACA -4691 -1606.0
PRKAG1 2103 -1806.0
PRKAG2 -3237 -3533.0
PRKAG3 -5537 -5285.0
PRKCQ -5095 -4882.0
PRMT5 933 1373.0
PRMT6 2063 4522.0
PRR5 -837 422.0
PSMA1 2820 3328.0
PSMA3 3434 -4.0
PSMA4 769 958.0
PSMA6 2199 -1044.0
PSMA7 -2980 976.0
PSMB1 954 2628.0
PSMB10 -1800 2907.0
PSMB2 618 2471.0
PSMB4 -235 2096.0
PSMB5 -4113 -606.0
PSMB6 -793 914.0
PSMB7 -831 -1453.0
PSMB8 -675 2066.0
PSMB9 -1611 -2973.0
PSMC1 449 -336.0
PSMC2 -1311 3241.0
PSMC3 -2439 -369.0
PSMC4 2724 1416.0
PSMC5 1212 -1123.0
PSMC6 -2520 3423.0
PSMD1 2619 -1191.0
PSMD10 -1227 525.0
PSMD11 995 5183.0
PSMD12 3831 536.0
PSMD13 821 1665.0
PSMD14 -635 3816.0
PSMD2 -713 -555.0
PSMD3 -3343 2226.0
PSMD4 -214 2558.0
PSMD5 1807 3558.0
PSMD6 3537 -2207.0
PSMD7 -2329 1233.0
PSMD8 -3171 4626.0
PSMD9 4204 -970.0
PSME1 -2771 3350.0
PSME2 -4085 3584.0
PSME3 3333 3379.0
PSME4 1960 -4574.0
PSMF1 683 -1480.0
PTEN 2797 2721.0
PTPN1 1531 4585.0
PTPN11 -1575 -666.0
PTPN4 -1408 3737.0
RABGGTA -1231 -2531.0
RABGGTB -945 568.0
RAD1 3205 3561.0
RAD17 2273 808.0
RAD50 306 -3473.0
RAD51 63 -2396.0
RAD51D -876 -2147.0
RAD9A -3149 -154.0
RARA -5250 2741.0
RARB -2995 -2000.0
RARG -4431 -4039.0
RB1 -2449 1464.0
RBBP4 1072 2469.0
RBBP5 4628 41.0
RBBP7 -924 -2291.0
RBBP8 3047 3316.0
RBFOX1 -5102 -4462.0
RBL1 -1617 778.0
RBL2 -242 -5105.0
RBM14 4731 4087.0
RBPJ 305 4930.0
RBX1 -733 -968.0
RELA 1783 4531.0
RFC2 622 -1170.0
RFC3 2151 4113.0
RFC4 3542 964.0
RFC5 1409 3528.0
RFFL 1079 -1551.0
RGCC -1145 5234.0
RHEB 172 2951.0
RHNO1 -4573 -113.0
RICTOR 3562 -2934.0
RING1 -1968 -125.0
RMI1 4517 -56.0
RMI2 -2759 -5106.0
RNF111 3964 4756.0
RNF2 3038 4651.0
RNF34 3719 -1122.0
RNGTT 4414 1057.0
RNMT 4864 -807.0
RNPS1 681 -379.0
RORA -5056 -2699.0
RORC -5248 -4317.0
RPA1 -1837 -4231.0
RPA2 2889 -1373.0
RPA3 2702 -1706.0
RPAP2 3147 -3300.0
RPRD1A -3380 -3404.0
RPRD1B 2187 -1926.0
RPRD2 4039 -351.0
RPS27A 783 1840.0
RPTOR -4596 2076.0
RQCD1 4265 347.0
RRAGA 2383 4477.0
RRAGB -366 -548.0
RRAGC 2091 945.0
RRAGD -4673 -5179.0
RRM2B -887 -4977.0
RTF1 -2993 -2893.0
RUNX1 -2434 4962.0
RUNX2 85 1728.0
RXRA -5519 -4191.0
RXRB -1250 -3372.0
RXRG -4055 1680.0
RYBP 4895 4575.0
SARNP 569 48.0
SATB2 3702 5210.0
SCMH1 -5007 -1597.0
SCO1 3577 1708.0
SCO2 -1941 -772.0
SERPINE1 -211 5168.0
SESN1 -4227 3713.0
SESN2 -2604 5137.0
SESN3 4513 -2160.0
SETD1A 2076 2948.0
SETD1B -3010 2327.0
SGK1 1084 -5256.0
SIN3A 3397 267.0
SIN3B 1030 2716.0
SIRT1 4935 4484.0
SIRT3 -2752 -5206.0
SKI -3187 1297.0
SKIL 1818 1156.0
SKP1 2028 -2504.0
SKP2 4205 4385.0
SLBP 2666 4952.0
SLC2A3 5004 2971.5
SLC38A9 969 -2953.0
SLU7 4893 3614.0
SMAD1 -2920 5081.0
SMAD2 1125 4898.0
SMAD3 -3794 -5343.0
SMAD4 2354 -52.0
SMAD6 2009 -2772.0
SMAD7 -1051 1964.0
SMARCA2 -2904 -5150.0
SMARCA4 -3874 -1402.0
SMARCB1 -474 3240.0
SMARCC1 -4311 -2069.0
SMARCC2 -3726 -493.0
SMARCD1 2718 2939.0
SMARCD2 319 937.0
SMARCD3 -5399 -4597.0
SMARCE1 1364 3960.0
SMURF1 4443 2060.0
SMURF2 1070 4724.0
SMYD2 -1305 -5129.0
SNAPC1 3749 4880.0
SNAPC2 3411 899.0
SNAPC3 3029 -1441.0
SNAPC4 363 -1786.0
SNAPC5 -703 -1692.0
SNRPB 3761 35.0
SNRPD3 2384 -1603.0
SNRPE 3421 760.0
SNRPF 3777 2400.0
SNRPG 3179 3615.0
SNW1 3618 4819.0
SOCS3 -283 5103.0
SOCS4 4713 2490.0
SOD2 -1568 -3943.0
SOX9 2175 5159.0
SP1 1787 -1016.0
SPP1 1162 3043.0
SRC -3910 1378.0
SREBF1 -5230 594.0
SRRM1 2285 -746.0
SRRT 4962 3050.0
SRSF1 1871 -429.0
SRSF11 3911 -4703.0
SRSF3 2586 3185.0
SRSF4 1929 4093.0
SRSF5 1997 -2886.0
SRSF6 1798 3296.0
SRSF7 3545 4305.0
SRSF9 3543 3246.0
SSRP1 1755 3948.0
SSU72 1324 -300.0
STAT1 236 -1738.0
STEAP3 -5586 -4653.0
STK11 -4884 -2152.0
STUB1 -2898 -690.0
SUMO1 4213 1399.0
SUPT16H 3885 4363.0
SUPT4H1 3648 -1203.0
SUPT5H 1321 3508.0
SUPT6H 4807 4811.0
SURF1 -1748 -4099.0
SUZ12 3871 1927.0
SYMPK -3207 -2811.0
TACO1 651 -4262.0
TAF1 1708 -350.0
TAF10 -273 2957.0
TAF11 2962 -484.0
TAF12 3100 3164.0
TAF13 4749 1567.0
TAF2 4591 3381.0
TAF3 4294 4474.0
TAF4 -1340 3063.0
TAF4B 4967 5209.0
TAF5 4309 2830.0
TAF6 -912 55.0
TAF7 4717 4909.0
TAF8 2937 1691.0
TAF9B 1874 519.0
TBL1XR1 1876 -2165.0
TBP 1137 2611.0
TCEA1 4037 647.0
TCF12 1614 4124.0
TCF3 -2289 2184.0
TCF7 1204 2448.0
TCF7L1 -3205 2935.0
TCF7L2 -74 -1755.0
TEAD1 -4292 -1880.0
TEAD2 323 -142.0
TEAD3 -4846 -3020.0
TEAD4 -5380 -3156.0
TFDP1 -2245 -2659.0
TFDP2 4029 -5361.0
TGFB1 -3111 4943.0
TGIF1 -2131 3663.0
THBS1 762 4431.0
THOC1 2868 2547.0
THOC2 4510 -4472.0
THOC3 2831 -1702.0
THOC5 4842 542.0
THOC6 -904 3700.0
THOC7 -873 -3339.0
THRA -5483 -5283.0
THRB -1313 -4788.0
TJP1 405 -3133.0
TMEM219 -3222 -1406.0
TMEM55B 3859 2821.0
TNFRSF10A -3936 1259.5
TNFRSF10B -1612 1259.5
TNFRSF10C -2321 1259.5
TNFRSF10D -3227 1259.5
TNKS1BP1 -4407 1783.0
TNRC6A 3585 -573.0
TNRC6B 3118 -4527.0
TNRC6C -2020 -1918.0
TOP3A 2607 1632.0
TOPBP1 2183 4567.0
TP53 575 3751.0
TP53BP2 4687 2493.0
TP53INP1 -2309 -3743.0
TP53RK 3992 1448.0
TP63 3691 -337.0
TPX2 3446 2359.0
TRIAP1 901 881.0
TRIM28 4209 4460.0
TRIM33 2796 2074.0
TRIM63 -4866 -2132.0
TSC1 2577 -2625.0
TSC2 -4999 -1090.0
TTC5 3302 82.0
TWIST1 2624 2962.0
TXN 1855 4791.0
TXNRD1 -2444 2445.0
U2AF2 4337 3060.0
UBC 2672 4480.0
UBE2C 4949 463.0
UBE2D1 -1588 -4032.0
UBE2D3 1424 4934.0
UBE2E1 -1132 -479.0
UBE2I 1246 1214.0
UBE2S 4441 4268.0
UPF3B 1586 -4316.0
USP2 -5039 -2958.0
USP7 3857 277.0
USP9X 1458 -4487.0
UXT -248 1342.0
VEGFA -4571 -5196.0
VWA9 2598 73.0
WDR33 3143 1005.0
WDR5 -1608 1773.0
WDR61 -1148 301.0
WRN 98 2665.0
WWOX 1055 -3182.0
WWP1 -1200 -5241.0
WWTR1 -2503 809.0
YAF2 182 -1698.0
YAP1 -476 3863.0
YEATS4 3247 4452.0
YES1 -176 -2941.0
YWHAB 3680 3415.0
YWHAE 1394 -914.0
YWHAG -2372 -3104.0
YWHAH -2777 4700.0
YWHAQ 963 3739.0
YWHAZ 2019 4495.0
ZC3H8 -3996 -3720.0
ZFHX3 -2823 -1477.0
ZFP1 777 1054.0
ZFP14 -1564 -2258.0
ZFP2 -2603 -3327.0
ZFP28 4189 -1082.0
ZFP30 516 -3758.0
ZFP37 4076 4532.0
ZFP69 3315 885.0
ZFP90 480 1431.0
ZFPM1 71 1174.0
ZIK1 4897 -4577.0
ZKSCAN1 -1405 2369.0
ZKSCAN3 630 -4083.5
ZKSCAN4 4031 -4083.5
ZKSCAN5 4612 4688.0
ZKSCAN7 -1769 -4260.0
ZKSCAN8 3190 -5273.0
ZNF101 4947 -3935.0
ZNF112 2487 -1819.0
ZNF12 2721 -2788.0
ZNF124 4126 -3935.0
ZNF143 1822 4417.0
ZNF169 -1838 -95.0
ZNF18 3432 3441.0
ZNF180 3868 -1454.0
ZNF189 1916 -3063.0
ZNF202 2190 2960.0
ZNF205 -2430 1761.0
ZNF212 554 651.0
ZNF213 -509 695.0
ZNF23 1671 -3290.0
ZNF235 2757 -5191.0
ZNF248 -2815 494.0
ZNF25 -3296 4123.0
ZNF250 -514 -194.0
ZNF263 4581 1183.0
ZNF274 4186 -4975.0
ZNF282 -3935 1751.0
ZNF286A 3048 -2213.0
ZNF287 3780 -3286.0
ZNF3 3939 -3789.0
ZNF317 3402 513.0
ZNF324 2644 130.5
ZNF324B 2800 130.5
ZNF334 961 3548.0
ZNF347 4334 -4237.5
ZNF354A 4577 -2881.0
ZNF354C 1442 -3786.0
ZNF385A -5211 4005.0
ZNF394 4721 -950.0
ZNF398 1779 1470.0
ZNF416 4497 197.0
ZNF420 16 2432.0
ZNF426 3687 378.0
ZNF429 -5017 -4708.5
ZNF43 4092 -4836.5
ZNF436 3688 -3750.0
ZNF445 -3447 -5082.0
ZNF446 -63 -3109.0
ZNF45 4715 -3085.0
ZNF454 921 -797.0
ZNF493 -3572 -4836.5
ZNF496 -2663 -213.0
ZNF521 629 312.0
ZNF551 4427 -1225.0
ZNF559 4814 -3313.5
ZNF560 3600 2855.0
ZNF561 -185 -2672.5
ZNF562 -55 -2672.5
ZNF566 549 996.0
ZNF569 2722 -3079.0
ZNF585A 4317 -3769.0
ZNF597 3559 -1334.0
ZNF606 1719 -4100.0
ZNF641 -4105 -2397.0
ZNF655 1508 4322.0
ZNF660 -856 -3726.0
ZNF664 -1330 1122.0
ZNF665 359 -4237.5
ZNF667 1646 -1140.0
ZNF668 3548 1490.0
ZNF669 4901 -3935.0
ZNF678 3662 -4615.0
ZNF688 -1703 3477.0
ZNF689 2277 3161.0
ZNF691 1491 -4306.0
ZNF692 -475 -2970.0
ZNF697 -787 4655.0
ZNF703 -5506 -3188.0
ZNF704 -3376 -1530.0
ZNF706 99 -2036.0
ZNF707 -1032 2031.0
ZNF710 -2142 -4869.0
ZNF720 4946 -5268.5
ZNF721 4971 -3955.5
ZNF738 4987 -5268.5
ZNF740 -4838 -3657.0
ZNF746 736 1942.0
ZNF764 -1896 3106.0
ZNF770 4367 -4912.0
ZNF771 107 1997.0
ZNF775 -3056 -2600.0
ZNF777 657 736.0
ZNF790 -3148 -2282.0
ZNF791 4620 -1735.0
ZNF839 -808 -82.0
ZSCAN25 2848 1801.0



Disease

Disease
metric value
setSize 1013
pMANOVA 1.15e-11
p.adjustMANOVA 4.71e-10
s.dist 0.135
s.human 0.00755
s.mouse 0.134
p.human 0.692
p.mouse 1.74e-12




Top 20 genes
Gene human mouse
TAF4B 4967 5209.0
HSPA1A 4887 5277.5
GTF2F1 4999 4919.0
TAF7 4717 4909.0
EZH2 4698 4740.0
GTF2B 4276 5124.0
GTF2A1 4730 4588.0
NUP98 4235 5066.0
CCNE1 4388 4753.0
PLK2 4764 4365.0
PTPN12 4141 5021.0
GTF2F2 4067 5069.0
RAP1B 4479 4565.0
BRD4 4547 4468.0
PTGER4 4219 4674.0
EXT1 3887 5027.0
MYC 3994 4886.0
POLR2A 3861 5046.0
NUS1 3898 4988.0
MSH6 4522 4295.0

Click HERE to show all gene set members

All member genes
human mouse
AAAS -3476 1550.0
ABCA1 1045 -4559.0
ABCA3 -5218 -2538.0
ABCC9 -3151 -5198.0
ABCD1 -5486 -4643.0
ABCD4 477 -3574.0
ABI1 3792 2553.0
ABI2 -308 5048.0
ABL1 -4533 -3545.0
ACTB 940 4977.0
ACTG1 -3075 4986.0
ACTR2 3547 3933.0
ACTR3 1376 5136.0
ADAM10 -1509 -1025.0
ADAM17 2407 2079.0
ADAMTS1 -4587 4708.0
ADAMTS10 -3598 -1942.0
ADAMTS12 -923 -2332.0
ADAMTS14 -4689 2235.0
ADAMTS15 -1197 -4341.0
ADAMTS2 -2757 54.0
ADAMTS20 4370 1679.0
ADAMTS4 -3160 4284.0
ADAMTS5 3535 -597.0
ADAMTS6 343 -2644.0
ADAMTS7 -4471 -2597.0
ADAMTS9 -783 -1149.0
ADAMTSL1 -1421 -1117.0
ADAMTSL2 -4455 -1524.0
ADAMTSL3 1820 -922.0
ADAMTSL4 -3703 -3880.0
ADAMTSL5 -4376 2796.0
ADCY1 -3780 -1927.0
ADCY2 -4820 -3731.0
ADCY3 338 187.0
ADCY5 1967 1780.0
ADCY6 -4515 -4206.0
ADCY7 -2820 2292.0
ADCY9 -4889 -4292.0
ADM -1822 -3261.0
ADRB2 -1092 -2389.0
AGGF1 2850 2956.0
AGK -3597 -1970.0
AGRN -4903 -2954.0
AGTRAP -3555 -1572.0
AHCY -4149 4640.0
AHCYL1 -3386 988.0
AKAP9 -573 -5181.0
AKT1 -4954 342.0
AKT1S1 271 -141.0
AKT2 -4057 -4450.0
AKT3 1343 -320.0
ALG1 -2082 823.0
ALG11 4862 545.0
ALG12 -2835 800.0
ALG14 -3661 -4074.0
ALG2 3171 1447.0
ALG3 74 2052.0
ALG6 474 -3883.0
ALG8 1362 3113.0
ALG9 3170 2253.0
AMER1 -2488 -4016.0
ANAPC1 572 -4087.0
ANAPC10 1974 2134.0
ANAPC11 -3265 -1751.0
ANAPC15 -3393 1787.0
ANAPC16 -3612 -1148.0
ANAPC2 -2185 -3532.0
ANAPC4 -720 -4834.0
ANAPC5 1284 -2104.0
ANAPC7 1595 2349.0
ANTXR1 -1237 -965.0
ANTXR2 -1075 1180.0
AP1B1 -4552 -34.0
AP1G1 4140 2569.0
AP1M1 3732 1437.0
AP1S1 -1410 812.0
AP1S2 -1634 1536.0
AP2A1 -3632 -420.0
AP2A2 -1058 5063.0
AP2B1 -1157 2251.0
AP2M1 -2746 3372.0
AP2S1 1777 1981.0
AP3B1 3180 3707.0
APC 3772 -1232.0
APH1A 204 -174.0
APH1B 3428 -1780.0
APP -2792 582.0
ARAF -3318 -4367.0
ARF1 566 4500.0
ARID4A 4673 -1405.0
ARID4B 4763 -2509.0
ARPC1A -120 2648.0
ARPC1B 669 4856.0
ARPC2 1357 4617.0
ARPC3 2873 3762.0
ARPC4 1698 2568.0
ARPC5 2295 4844.0
ARRB1 -3133 -14.0
ARRB2 -1089 4317.0
ARSB -1001 2832.0
ATG7 -1364 1374.0
ATP1A1 -4096 4907.0
ATP1A2 -5569 -5156.0
ATP1A3 206 3822.0
ATP1B1 2576 -3091.0
ATP1B3 -598 3075.0
ATP6V1H -57 4488.0
AXIN1 -730 3618.0
B2M -731 1593.0
B3GALT6 -1251 4136.0
B3GAT3 -4234 1339.0
B4GALT1 -1314 2589.0
B4GALT7 -4152 -1537.0
BAD -1537 3476.0
BAG4 4135 2734.0
BAIAP2 -641 5041.0
BANF1 -2281 674.0
BCL2L11 -4974 2480.0
BCR 4627 2917.0
BDNF 1086 5114.0
BECN1 3274 -3060.0
BGN -1474 3919.0
BRAF 4103 1387.0
BRAP 4689 3899.0
BRD4 4547 4468.0
BRK1 2026 3096.0
BRMS1 -28 2515.0
BSG -2248 -2113.0
BTD 2566 2195.0
BTRC -1187 -2758.0
C1GALT1 1968 -1085.0
C1GALT1C1 1294 225.0
C1QBP 3798 -456.0
C3 4311 1838.0
CALCRL 2945 -4855.0
CALM1 -4464 96.0
CALR 1534 4995.0
CAMK2A -5527 -4430.0
CAMK2B -5497 -4230.0
CAMK2D -2223 4137.0
CAMK2G -2097 -4962.0
CANX -836 4736.0
CAPN1 -5166 -4425.0
CAPN2 -3411 4931.0
CAPNS1 -1346 1750.0
CASP1 -1298 3173.0
CASP8 -1646 3092.0
CASP9 -3269 -2569.0
CAST -753 4871.0
CBL 1736 183.0
CBLL1 4088 2387.0
CBX1 3736 453.0
CCNC 4650 3537.0
CCND1 757 529.0
CCND2 225 405.0
CCND3 786 1371.0
CCNE1 4388 4753.0
CCNE2 4667 147.0
CCNH 3825 -1657.0
CCNK 3139 154.0
CCNT1 4896 -1160.0
CCNT2 4381 -5015.0
CD28 -2910 -5023.0
CD320 -2432 -726.0
CD36 -582 -3838.0
CD9 2203 2358.0
CDC16 86 -1984.0
CDC23 3850 -1171.0
CDC25A 4090 2308.0
CDC25B 4652 2780.0
CDC26 2750 2457.0
CDC27 665 1230.0
CDC37 -1724 -675.0
CDC42 3308 754.0
CDK2 849 2686.0
CDK4 703 3417.0
CDK5 -1007 -793.0
CDK6 1090 3036.0
CDK7 1571 -2032.0
CDK8 623 -1722.0
CDK9 -1348 4462.0
CDKN1A -4927 5092.0
CDKN1B -3284 -2450.0
CDKN1C -5394 -4228.0
CHD3 -3721 -4142.0
CHD4 -4283 464.0
CHMP1A 2879 123.0
CHMP2A 1155 2310.0
CHMP2B 967 -4167.0
CHMP3 -3919 1578.0
CHMP4B -1125 329.0
CHMP5 3372 -357.0
CHMP6 -4368 279.0
CHMP7 1743 -3701.0
CHST14 -3829 1240.0
CHST3 -4526 4276.0
CHSY1 3804 1910.0
CHUK 216 955.0
CLCN6 -4710 -1423.0
CLTA 1218 1668.0
CLTC 2268 -2802.0
CNKSR1 -2870 3756.0
CNTRL 4333 -5162.0
COMT -5098 -1696.0
CPSF4 862 4036.0
CPSF6 2963 2942.0
CRBN -992 -4556.0
CREB1 2179 -4329.0
CREBBP 1506 3139.0
CRK 2145 2262.0
CSK -3610 4738.0
CSPG4 -5621 538.0
CTBP1 -3458 -2615.0
CTBP2 760 -812.0
CTDP1 2071 4335.0
CTNNB1 1714 -780.0
CTNND1 949 4751.0
CTSA -3537 -2181.0
CUL1 -3121 -1536.0
CUL5 2599 -3195.0
CUX1 -3622 -3289.0
CYBA -633 3083.0
CYFIP2 -3775 -1129.0
CYP26B1 -756 -2217.0
CYP27A1 -4508 -5335.0
CYP2U1 -3305 -2764.0
CYSLTR1 -4110 4015.0
DAD1 498 2970.0
DAG1 -5236 2687.0
DAXX 4449 4197.0
DBP -538 -5331.0
DCN -1048 -896.0
DCXR -3844 -362.0
DDOST 320 4699.0
DDX5 4191 -2760.0
DERL1 3289 24.0
DERL2 2481 3828.0
DHDDS 2100 2602.0
DKK2 -348 -1527.0
DLL1 -3980 -4227.0
DNAJC3 1950 1334.0
DOCK1 -226 -41.0
DOLK -82 -1243.0
DPAGT1 2728 1591.0
DPM1 4455 -3334.0
DPM2 1390 4233.0
DPM3 -2695 1529.0
DUSP10 -5329 2114.0
DUSP16 3082 2356.0
DUSP6 -528 -1256.0
DUSP7 -3477 -3537.0
DUSP8 1715 4654.0
DUT -592 540.0
DVL1 -5428 -3357.0
DVL2 -2215 -2076.0
DVL3 -4897 87.0
DYNC1H1 -1442 -2348.0
DYNC1I2 2591 -2971.0
DYNC1LI1 2883 1316.0
DYNC1LI2 1750 -1620.0
DYNLL1 -1331 4245.0
E2F1 -529 4663.0
E2F3 -4683 -1694.0
EDEM2 1319 3509.0
EED 3304 3671.0
EEF2 -2853 -853.0
EGF -4568 -5354.0
EGFR 424 1475.0
EIF2AK2 -486 -749.0
ELK1 -3862 -42.0
ELL -3990 3019.0
ELMO1 -2166 1449.0
ELMO2 -354 416.0
ENO1 -4083 2473.0
ENTPD5 -4035 -3417.0
EP300 3403 -1622.0
EPM2A -579 -4793.0
EPS15 5 -4281.0
ERBB2 -5511 673.0
ERBB3 -5290 -2790.0
ERCC2 824 2393.0
ERCC3 473 1570.0
ERLEC1 2742 -3168.0
ERLIN1 1762 4635.0
ERLIN2 -802 1500.0
ESR1 -1770 -3364.0
ETV6 -5186 2743.0
EXT1 3887 5027.0
EXT2 2074 919.0
EZH2 4698 4740.0
F8 -941 -4201.0
FADD -571 4877.0
FAM114A2 2881 -4355.0
FAU 2272 4115.0
FBXW7 -886 -330.0
FDX1 2337 4039.0
FDXR -4136 -3282.0
FEN1 4094 3551.0
FGF1 798 5215.0
FGF2 751 -1095.0
FGF7 -5445 2606.0
FGF9 -5320 -3468.0
FGFR1 -1499 -3421.0
FGFR1OP2 3988 -2235.0
FGFR3 3759 4128.0
FGFR4 -5312 -3374.0
FIP1L1 3587 1848.0
FKBP4 1305 500.0
FMOD -329 -1294.0
FN1 35 4022.0
FOXO1 -432 1302.0
FOXO3 -42 -1131.0
FOXO4 -3493 -4492.0
FOXO6 -4157 -4011.0
FRS2 4678 761.0
FURIN -4221 4117.0
FUT8 3313 438.0
FXR1 2325 -4598.0
FXYD1 -2722 -3530.0
FYN -2850 3685.0
FZD4 -5151 -4512.0
FZD5 398 4746.0
FZD6 809 -1518.0
FZD7 1006 -4275.0
FZD8 -3582 -1275.0
FZR1 -1244 3620.0
G6PC3 -3066 -1492.0
GAA -5001 -3369.0
GAB1 -1853 -2427.0
GAB2 4053 2422.0
GALE -4804 2903.0
GALK1 -3470 2667.0
GALNS -3960 4545.0
GALNT1 1478 1252.0
GALT -2687 -4117.0
GANAB 489 2629.0
GATAD2A -975 4779.0
GATAD2B 304 3259.0
GBE1 532 -3437.0
GCLC 2502 4184.0
GCLM -818 -474.0
GFPT1 3386 2993.0
GGCX -1810 -3457.0
GGT5 -954 -1159.0
GLB1 -2244 924.0
GNAI1 183 -419.0
GNAI2 800 3632.0
GNAI3 4221 3815.0
GNAS -3163 -641.0
GNB1 177 4937.0
GNB2 -3870 3905.0
GNB3 -3272 -1723.0
GNB4 -3491 -3375.0
GNB5 879 160.0
GNE 3149 -2930.0
GNG11 4695 -2336.0
GNG12 612 -821.0
GNG2 802 -279.0
GNG5 415 -1583.0
GNG7 -2742 -5085.0
GNS 101 -979.0
GOLGA2 919 -3262.0
GOLGA4 2988 -4090.0
GPC1 -5269 -2966.0
GPC4 -5170 -3500.0
GPC6 -2385 158.0
GPS2 2002 3298.0
GRB2 -4050 4496.0
GRSF1 -3131 -4623.0
GSK3A 3319 -75.0
GSK3B 897 3200.0
GSS -4919 4656.0
GTF2A1 4730 4588.0
GTF2A2 4648 -1742.0
GTF2B 4276 5124.0
GTF2E1 2188 1803.0
GTF2E2 2041 120.0
GTF2F1 4999 4919.0
GTF2F2 4067 5069.0
GTF2H1 3886 1058.0
GTF2H2 4419 -2446.5
GTF2H3 -1925 467.0
GTF2H5 -878 -1711.0
GUSB 1923 4153.0
GYG1 -3875 4435.0
GYS1 -5384 -4666.0
HBEGF 3484 5272.0
HDAC10 -3116 -2283.0
HDAC11 -4482 3956.0
HDAC2 4386 -1101.0
HDAC3 -178 -4320.0
HDAC4 -5061 -4325.0
HDAC5 -4921 2376.0
HDAC6 -4164 3925.0
HDAC7 -3827 -2596.0
HDAC8 209 -3381.0
HDAC9 -3759 2762.0
HEPH -3258 -1040.0
HES1 1695 -1766.0
HEXA -221 1746.0
HEXB 753 2379.0
HEY1 4826 451.0
HEYL -2812 2440.0
HGS 2410 4643.0
HGSNAT -4600 -3529.0
HHAT 2490 3704.0
HK1 -4205 2075.0
HLCS -758 -3900.0
HMG20B 704 291.0
HMGA1 598 5099.0
HNRNPK 3054 2784.0
HRAS -4545 -3997.0
HSP90AA1 3656 5261.0
HSP90AB1 -639 4629.0
HSPA1A 4887 5277.5
HSPG2 -5351 -404.0
HTR7 2315 -1558.0
HYAL1 -3845 1605.0
IDH1 1160 -5189.0
IDS -2473 -3621.0
IDUA -3866 -4738.0
IFNAR1 3645 1085.0
IFNAR2 -1316 2360.0
IFNGR1 2506 2475.0
IFNGR2 -386 -4286.0
IKBKB -4093 578.0
IL1R1 -3018 3910.0
IL6R -5515 3267.0
IMPDH1 -827 2546.0
IMPDH2 822 1907.0
IPO5 1982 3806.0
IQGAP1 -415 3217.0
IRAK4 -569 1975.0
IRS1 -5550 -5121.0
IRS2 3384 2684.0
ISG15 -3928 1737.0
ITGA4 -2878 -5141.0
ITGB1 956 4614.0
ITGB3 -488 4915.0
ITPR1 4903 -2230.0
ITPR2 1242 -3115.0
ITPR3 -3631 -3441.0
JAG1 3237 -2093.0
JAG2 -5593 -2334.0
JAK1 -1869 4228.0
JAK2 -2569 -5057.0
JUN 2469 5225.0
KANK1 -2800 550.0
KAT2A -5053 -1162.0
KAT2B -3340 -5260.0
KCNJ11 -5488 -2118.0
KDM1A 249 4852.0
KERA 526 -850.0
KHK 4875 -2587.0
KIAA1549 -1875 2054.0
KITLG 4898 -4811.0
KPNA1 1833 3439.0
KPNA2 5007 3593.0
KPNA3 -2337 -1621.0
KPNA4 1501 4518.0
KPNB1 3619 3517.0
KRAS 3546 4454.0
KREMEN1 -5547 -2837.0
KSR1 -5578 -5013.0
LFNG 160 3175.0
LIG1 -3127 3257.0
LIG4 2394 -3296.0
LMBRD1 310 -1913.0
LMNA -4692 5155.0
LMNB1 3392 2947.0
LRP5 -5463 -1746.5
LRP6 -277 -680.0
LRRFIP1 -4175 -4627.0
LUM -1839 2479.0
LYN 785 3984.0
MAGT1 1192 -1341.0
MAML1 2770 4603.0
MAML2 2681 640.0
MAML3 -2079 -345.0
MAMLD1 -1668 1073.0
MAN1B1 -2087 -721.0
MAN2A1 4002 1427.0
MAOA -96 3927.0
MAP1LC3B 2569 -3268.0
MAP2K1 -506 -2643.0
MAP2K2 -3813 -1797.0
MAP2K3 -4716 3039.0
MAP2K4 8 -3251.0
MAP2K6 1456 -4876.0
MAP2K7 794 -3887.0
MAP3K11 -3624 1948.0
MAPK1 1988 -648.0
MAPK14 -1562 -1635.0
MAPK3 -1024 3725.0
MAPK8 457 1106.0
MAPKAP1 -405 2624.0
MARK3 3178 -2043.0
MBD3 -3419 1364.0
MCCC1 4013 -4691.0
MCCC2 2204 -4968.0
MDM2 3253 3321.0
MECP2 -1705 -4130.0
MET -3529 2929.0
MGAT1 -1603 -2422.0
MGAT2 1418 4950.0
MGAT4A 268 3317.0
MGAT4B -4707 -1206.0
MGAT5 3014 2727.0
MIB1 1332 -3751.0
MIB2 -4266 698.0
MLH1 -1210 -4562.0
MLST8 -3485 -2266.0
MMAA 2798 -4327.0
MMAB -5378 -5342.0
MMACHC 1931 -3355.0
MMADHC 3242 -1038.0
MNAT1 830 -2433.0
MOGS -3129 4652.0
MPDU1 2237 1141.0
MPI -5533 -4782.0
MPRIP -4080 -1463.0
MRAS -5239 941.0
MSH2 4647 -5020.0
MSH3 4256 -3845.0
MSH6 4522 4295.0
MTA1 -4102 4542.0
MTA2 3682 946.0
MTA3 -2123 -1614.0
MTOR -1191 -1922.0
MTR 2939 -4500.0
MTRR 2177 3264.0
MUTYH 2615 656.0
MVB12A -2807 711.0
MVB12B -5576 -5074.0
MYC 3994 4886.0
MYD88 2726 4679.0
MYH2 -3080 -857.0
MYH9 -1879 4194.0
MYO10 1381 294.0
MYO18A -5555 3936.0
MYO1C -4842 3521.0
MYO5A -885 3279.0
MYO9B -1901 4055.0
NAGLU -3708 -713.0
NAPEPLD -3083 3042.0
NCBP1 -1736 4182.0
NCBP2 4188 264.0
NCK1 3718 1288.0
NCKAP1 3563 3585.0
NCKIPSD -2821 704.0
NCOR1 2625 -3925.0
NCOR2 -5167 -1521.0
NCSTN -2504 1262.0
NDC1 1273 -2350.0
NEDD4L 4279 -2158.0
NEIL1 -3522 -3044.0
NELFA 356 3929.0
NELFB -1196 2773.0
NELFCD 1896 -2294.0
NELFE -2178 3334.0
NEU1 1863 4218.0
NEURL1B -4776 -656.0
NF1 3095 3333.0
NFKB1 -4233 3315.0
NFKB2 -3926 3336.0
NFKBIA -4263 4096.0
NHLRC1 -3454 3917.0
NMT1 -1463 3596.0
NMT2 2059 2124.0
NOTCH1 -5460 44.0
NOTCH3 -1225 773.0
NR3C1 985 -4192.0
NR4A1 -5560 -642.0
NRAS 4354 69.0
NT5E 1998 -3634.0
NTHL1 -3527 -4319.0
NUP107 3232 2949.0
NUP133 889 -4048.0
NUP153 4762 1533.0
NUP155 4306 -2233.0
NUP160 3998 1035.0
NUP188 2117 3830.0
NUP205 4438 3588.0
NUP214 3124 665.0
NUP35 4571 649.0
NUP37 -327 192.0
NUP43 4562 2216.0
NUP54 4508 3831.0
NUP85 3181 -393.0
NUP88 1244 2212.0
NUP93 -1503 3903.0
NUP98 4235 5066.0
NUS1 3898 4988.0
OGG1 -4021 756.0
OGN 1004 -1845.0
OPLAH -2761 -4761.0
OS9 -1493 687.0
P2RX4 -1108 2865.0
PACS1 -4826 1664.0
PAK2 1525 4805.0
PAPSS1 4253 2351.0
PAPSS2 1717 384.0
PARP1 -2423 -2631.0
PARP10 -4978 -2806.0
PARP14 -1721 -1087.0
PARP16 -79 -2268.0
PARP4 -4440 2701.0
PARP6 448 419.0
PARP8 4194 1232.0
PARP9 -3114 22.0
PC -5226 -3696.0
PCCA -2597 -5205.0
PCCB -165 -4143.0
PDCD6IP 1350 4607.0
PDGFA -4328 -4456.0
PDGFB -606 3347.0
PDGFRA 2727 -349.0
PDGFRB -2260 1386.0
PDPK1 3443 2222.0
PEBP1 -3678 -1052.0
PGK1 -1414 -3515.0
PGM1 -4270 -4493.0
PHB -586 -2116.0
PHF21A -4739 -629.0
PIK3AP1 966 3680.0
PIK3C3 3439 -1648.0
PIK3CA 365 2811.0
PIK3CB 2760 4994.0
PIK3CD -4322 -4161.0
PIK3R1 2896 -3147.0
PIK3R3 3188 577.0
PIK3R4 3839 -3531.0
PLCG1 -3955 -4939.0
PLK2 4764 4365.0
PML 3338 3449.0
PMM2 3539 625.0
PMS2 806 -1784.0
POLR2A 3861 5046.0
POLR2B 4509 -4119.0
POLR2C 4529 -904.0
POLR2D 1669 2692.0
POLR2E -667 1599.0
POLR2G 89 5112.0
POLR2H -3927 3497.0
POLR2I -154 81.0
POLR2K 2480 -1584.0
POLR2L -4314 4110.0
POMGNT1 -3434 2668.0
POMT1 -3096 -1930.0
POMT2 -2224 974.0
PORCN 647 -2851.0
PPIA -4031 4697.0
PPP1CB -1374 -4149.0
PPP1CC 4081 399.0
PPP1R3C -5015 4049.0
PPP2CA 4482 3008.0
PPP2CB 2458 4129.0
PPP2R1A -4013 -696.0
PPP2R1B 3028 4619.0
PPP2R5A 4590 4219.0
PPP2R5B -1524 121.0
PPP2R5C -2508 -3684.0
PPP2R5D -3449 -2058.0
PPP2R5E 4644 1539.0
PRDX1 605 1340.0
PRDX2 -5293 -2557.0
PRKACA -4691 -1606.0
PRKACB -2659 -1546.0
PRKAR1A -3106 3030.0
PRKAR1B -2442 2761.0
PRKAR2A -2664 -655.0
PRKAR2B 3460 2616.0
PRKCSH -268 539.0
PRKX -1471 4883.0
PRR5 -837 422.0
PSEN1 2070 2061.0
PSEN2 -5371 -1458.0
PSENEN -2638 482.0
PSIP1 3390 2882.0
PSMA1 2820 3328.0
PSMA3 3434 -4.0
PSMA4 769 958.0
PSMA6 2199 -1044.0
PSMA7 -2980 976.0
PSMB1 954 2628.0
PSMB10 -1800 2907.0
PSMB2 618 2471.0
PSMB4 -235 2096.0
PSMB5 -4113 -606.0
PSMB6 -793 914.0
PSMB7 -831 -1453.0
PSMB8 -675 2066.0
PSMB9 -1611 -2973.0
PSMC1 449 -336.0
PSMC2 -1311 3241.0
PSMC3 -2439 -369.0
PSMC4 2724 1416.0
PSMC5 1212 -1123.0
PSMC6 -2520 3423.0
PSMD1 2619 -1191.0
PSMD10 -1227 525.0
PSMD11 995 5183.0
PSMD12 3831 536.0
PSMD13 821 1665.0
PSMD14 -635 3816.0
PSMD2 -713 -555.0
PSMD3 -3343 2226.0
PSMD4 -214 2558.0
PSMD5 1807 3558.0
PSMD6 3537 -2207.0
PSMD7 -2329 1233.0
PSMD8 -3171 4626.0
PSMD9 4204 -970.0
PSME1 -2771 3350.0
PSME2 -4085 3584.0
PSME3 3333 3379.0
PSME4 1960 -4574.0
PSMF1 683 -1480.0
PTEN 2797 2721.0
PTGER4 4219 4674.0
PTGES3 1328 3635.0
PTGIR -370 3143.0
PTH1R -2770 -1748.0
PTHLH -3836 1237.0
PTK2 -2497 -1508.0
PTPN11 -1575 -666.0
PTPN12 4141 5021.0
PYCARD -2810 4703.0
QKI 1019 -1699.0
RAB5A 2109 4941.0
RAB7A -383 1499.0
RAC1 2525 1457.0
RAC2 41 4946.0
RAE1 4471 2389.0
RAF1 1712 -1646.0
RAMP1 -5448 209.0
RAN 2329 1938.0
RANBP1 745 4765.0
RANBP2 4470 -3848.0
RANGAP1 483 4340.0
RAP1A -689 3710.0
RAP1B 4479 4565.0
RB1 -2449 1464.0
RBBP4 1072 2469.0
RBBP7 -924 -2291.0
RBP1 2113 1028.0
RBPJ 305 4930.0
RBX1 -733 -968.0
RCC1 997 3619.0
RCOR1 4776 -5.0
RDH5 -3933 1325.0
RELA 1783 4531.0
REST 1113 2305.0
RFT1 1838 -2586.0
RHBDF2 -2750 -644.0
RHOG -1207 4926.0
RICTOR 3562 -2934.0
RIPK1 325 719.0
RNF185 -3422 3292.0
RNF213 -4087 -1339.0
RNF5 -1204 -3852.0
RNGTT 4414 1057.0
RNMT 4864 -807.0
ROCK1 4876 -54.0
ROCK2 2205 314.0
RPIA 1665 -1013.0
RPL10 -3902 3841.0
RPL11 -2249 2690.0
RPL14 433 1505.0
RPL18 -1782 3926.0
RPL18A -2969 1546.0
RPL19 -502 2402.0
RPL22 1231 -695.0
RPL22L1 3380 4103.0
RPL23 -115 2472.0
RPL26 1047 3247.0
RPL28 -391 2871.0
RPL3 -786 4892.0
RPL30 286 2070.0
RPL31 -595 4273.0
RPL32 -367 2766.0
RPL34 1447 1856.0
RPL35A 812 1955.0
RPL36A 1261 2266.0
RPL37 -715 2388.0
RPL37A -1043 2280.0
RPL38 231 3306.0
RPL3L -5212 -3395.0
RPL4 -522 1026.0
RPL5 1206 4486.0
RPL7 1440 1916.0
RPL8 -2775 2474.0
RPLP2 -2469 2383.0
RPN1 768 1558.0
RPN2 497 3166.0
RPS11 -1582 3395.0
RPS12 -318 3958.0
RPS13 1131 3118.0
RPS14 -1412 1322.0
RPS15 -1799 1989.0
RPS15A -704 2410.0
RPS16 -1828 3864.0
RPS18 -974 2916.0
RPS19 -2045 2954.0
RPS20 -1844 4785.0
RPS21 -1536 707.0
RPS23 -68 1922.0
RPS24 256 1742.0
RPS26 -282 2982.0
RPS27A 783 1840.0
RPS27L -616 298.0
RPS29 -1140 2499.0
RPS3 -544 3102.0
RPS4X 83 1892.0
RPS5 -1577 2419.0
RPS6 -245 3549.0
RPS6KB2 -4132 2252.0
RPS8 -1593 2271.0
RPS9 -1107 1580.0
S1PR1 2689 1552.0
SAP18 4832 915.0
SAP30 138 3376.0
SAP30L -2519 -2355.0
SDC1 -2046 212.0
SDC2 1756 4483.0
SDC3 -4619 2809.0
SDC4 -2393 5153.0
SEC13 730 1702.0
SEH1L 1085 4263.0
SEL1L 3241 -1874.0
SEMA5A 485 -2610.0
SERPING1 78 286.0
SFPQ 4544 3976.0
SGSH 710 -512.0
SH3GL1 -2937 2592.0
SH3KBP1 1014 -3709.0
SHC1 3976 3605.0
SHOC2 4514 2152.0
SIGMAR1 -3608 2508.0
SIN3A 3397 267.0
SKP1 2028 -2504.0
SKP2 4205 4385.0
SLC11A2 -1944 1168.0
SLC12A6 2061 -3826.0
SLC16A1 -987 5075.0
SLC17A5 -4420 -1077.0
SLC1A1 1616 -966.0
SLC1A3 -1174 -2354.0
SLC20A2 -5063 -3585.0
SLC22A5 -4653 -2940.0
SLC25A4 -1327 -2889.0
SLC25A5 3467 4820.0
SLC26A2 1389 2030.0
SLC27A4 -453 1686.0
SLC29A3 -246 1291.0
SLC2A1 -2288 4737.0
SLC2A10 -5252 499.0
SLC33A1 -889 3463.0
SLC35A1 -814 -3604.0
SLC35A2 -798 1423.0
SLC35A3 -880 -2443.0
SLC35C1 504 3754.0
SLC35D1 1549 173.0
SLC36A2 -2334 -146.0
SLC37A4 -4766 -5052.0
SLC3A2 -656 3875.0
SLC40A1 -3081 5149.0
SLC4A4 -1068 -4399.0
SLC7A7 -3748 134.0
SLC9A6 2010 -1985.0
SLC9A9 -3500 2233.0
SMAD2 1125 4898.0
SMAD3 -3794 -5343.0
SMAD4 2354 -52.0
SND1 -1119 4259.0
SNF8 -1018 -1422.0
SNW1 3618 4819.0
SOD2 -1568 -3943.0
SOS1 -1962 -1007.0
SPON2 -4146 2334.0
SPRED1 3312 3519.0
SPRED2 1200 -423.0
SPRED3 -2447 -1440.0
SRC -3910 1378.0
SRD5A3 3461 2937.0
SSRP1 1755 3948.0
ST3GAL1 -4505 4024.0
ST3GAL2 -2316 -4984.0
ST3GAL3 -4844 -2274.0
ST3GAL4 -2946 3771.0
ST6GAL1 -5388 1754.0
ST6GALNAC2 -4576 1758.0
ST6GALNAC4 -4958 4122.0
STAM 3932 2747.0
STAM2 3489 2601.0
STAT1 236 -1738.0
STAT2 -2601 280.0
STAT3 -3885 5061.0
STAT5A -4125 -4573.0
STAT5B -5022 -5306.0
STRN -104 2814.0
STT3A -1709 4540.0
STX1A -411 1613.0
STX1B -468 -1328.0
SUDS3 3840 -2057.0
SUGT1 3140 -4533.0
SUMO1 4213 1399.0
SUPT16H 3885 4363.0
SUPT4H1 3648 -1203.0
SUPT5H 1321 3508.0
SUZ12 3871 1927.0
SYVN1 -192 4796.0
TAF1 1708 -350.0
TAF10 -273 2957.0
TAF11 2962 -484.0
TAF12 3100 3164.0
TAF13 4749 1567.0
TAF2 4591 3381.0
TAF3 4294 4474.0
TAF4 -1340 3063.0
TAF4B 4967 5209.0
TAF5 4309 2830.0
TAF6 -912 55.0
TAF7 4717 4909.0
TAF9B 1874 519.0
TALDO1 -2080 -766.0
TBK1 673 3485.0
TBL1XR1 1876 -2165.0
TBP 1137 2611.0
TCEA1 4037 647.0
TCF7L2 -74 -1755.0
TCN2 -1729 -2170.0
TFDP1 -2245 -2659.0
TFDP2 4029 -5361.0
TGFB1 -3111 4943.0
TGFBR1 -2914 981.0
TGFBR2 -927 1736.0
THBS1 762 4431.0
THBS2 379 -717.0
THSD1 -697 395.0
THSD4 2915 -1690.0
THSD7A 4873 -4362.0
TICAM1 1624 4371.0
TIRAP -2943 -3631.0
TLN1 -3918 2975.0
TLR3 -310 -3710.0
TLR4 1065 4916.0
TLR5 -3234 927.0
TLR6 888 1296.0
TNKS 2621 2015.0
TNKS2 4726 -3651.0
TPMT 2687 -1981.0
TPR 2984 -1026.0
TPST1 2003 1582.0
TPST2 -2855 -1220.0
TRADD -706 -1473.0
TRAF2 -1546 980.0
TRAF3 -3815 2462.0
TRAK1 -3001 -3401.0
TRIM24 -175 -4532.0
TRIM27 4120 4461.0
TRIM28 4209 4460.0
TSC2 -4999 -1090.0
TSG101 260 2655.0
TUBB -3118 5070.0
TUSC3 70 2722.0
TXN 1855 4791.0
TXNRD1 -2444 2445.0
TYK2 -3123 -50.0
UBAP1 -1913 4784.0
UBC 2672 4480.0
UBE2C 4949 463.0
UBE2D1 -1588 -4032.0
UBE2E1 -1132 -479.0
UBE2I 1246 1214.0
UBE2S 4441 4268.0
UVRAG 3046 3931.0
VAMP1 -3322 -4688.0
VAMP2 -3293 1812.0
VAV2 -4959 -899.0
VAV3 187 -1063.0
VCAN 1679 4433.0
VCL -4538 5034.0
VEGFA -4571 -5196.0
VPS33B 1266 1235.0
VPS36 -3053 -4109.0
VPS37A 1868 -4488.0
VPS37B -3496 2909.0
VPS37C 1403 3419.0
VPS4A -1545 -2086.0
VPS4B 4523 1960.0
VTA1 3283 447.0
VWF -779 -106.0
WASF2 -4656 1511.0
WASF3 -1015 718.0
WASL 2683 3268.0
WDR48 2310 408.0
WIPF1 -2552 1682.0
WIPF2 3299 -502.0
WIPF3 -5107 -5055.0
WNT5A 1837 -2457.0
XPO1 990 1809.0
XRCC4 -4731 -1301.0
XRCC5 4010 -2853.0
XRCC6 3225 -1241.0
YES1 -176 -2941.0
YWHAB 3680 3415.0
YWHAE 1394 -914.0
ZC3HAV1 -3132 2965.0
ZCRB1 833 -1382.0
ZFYVE9 -3150 -4894.0
ZMYM2 1664 -2236.0



Pyruvate metabolism and Citric Acid (TCA) cycle

Pyruvate metabolism and Citric Acid (TCA) cycle
metric value
setSize 49
pMANOVA 1.25e-11
p.adjustMANOVA 4.99e-10
s.dist 0.618
s.human -0.263
s.mouse -0.559
p.human 0.00145
p.mouse 1.28e-11




Top 20 genes
Gene human mouse
D2HGDH -4890 -5334
RXRA -5519 -4191
SDHA -4773 -4591
IDH2 -5216 -3854
SLC16A3 -4751 -4158
PDK2 -5450 -3535
OGDH -5268 -3650
ACO2 -3822 -4426
VDAC1 -2909 -4606
IDH3G -4178 -3128
MDH2 -4361 -2855
MPC1 -3681 -3235
SDHC -3712 -3001
PDHA1 -2405 -4451
PDP1 -2175 -4603
ADHFE1 -4039 -2474
PPARD -4213 -2337
GSTZ1 -2068 -4631
LDHA -3251 -2911
IDH3A -2155 -3823

Click HERE to show all gene set members

All member genes
human mouse
ACO2 -3822 -4426
ADHFE1 -4039 -2474
BSG -2248 -2113
CS 3653 -3566
D2HGDH -4890 -5334
DLAT -1960 -3824
DLD 1187 -4737
DLST -323 -3527
FAHD1 -1771 -4302
FH 287 -2895
GLO1 -678 -3885
GSTZ1 -2068 -4631
HAGH -4509 1245
IDH2 -5216 -3854
IDH3A -2155 -3823
IDH3B -2881 -2173
IDH3G -4178 -3128
L2HGDH -262 -3641
LDHA -3251 -2911
LDHB -1491 -1974
MDH2 -4361 -2855
ME1 1789 -3959
ME2 -1789 3526
ME3 4207 -3719
MPC1 -3681 -3235
MPC2 829 -1736
NNT -3325 -2371
OGDH -5268 -3650
PDHA1 -2405 -4451
PDHB -133 -3995
PDHX -126 -3872
PDK1 4600 -3234
PDK2 -5450 -3535
PDK3 4747 4864
PDK4 -712 -5238
PDP1 -2175 -4603
PDP2 -2619 -2438
PDPR -632 -4831
PPARD -4213 -2337
RXRA -5519 -4191
SDHA -4773 -4591
SDHB 431 -3707
SDHC -3712 -3001
SLC16A1 -987 5075
SLC16A3 -4751 -4158
SUCLA2 1517 -4376
SUCLG1 -31 -2136
SUCLG2 -1167 -4291
VDAC1 -2909 -4606



Signaling by Interleukins

Signaling by Interleukins
metric value
setSize 278
pMANOVA 2.95e-11
p.adjustMANOVA 1.14e-09
s.dist 0.232
s.human -0.0542
s.mouse 0.226
p.human 0.123
p.mouse 1.24e-10




Top 20 genes
Gene human mouse
CDKN1A -4927 5092
ANXA2 -4123 5025
STAT3 -3885 5061
PPIA -4031 4697
CSF1 -4242 4358
MSN -3907 4668
GRB2 -4050 4496
IL6R -5515 3267
BCL2L1 -5181 3434
NFKBIA -4263 4096
IL4R -3335 4935
TNFRSF1A -4666 3362
IRAK2 -4255 3633
TGFB1 -3111 4943
PSMD8 -3171 4626
PSME2 -4085 3584
VIM -3027 4772
HMOX1 -2843 5071
MAP2K3 -4716 3039
NFKB1 -4233 3315

Click HERE to show all gene set members

All member genes
human mouse
AIP -707 -1563
AKT1 -4954 342
ANXA1 537 4544
ANXA2 -4123 5025
APP -2792 582
ARF1 566 4500
ATF1 3129 3014
ATF2 3130 1863
BCL2 -4633 -1108
BCL2L1 -5181 3434
BCL6 -5018 -4816
BRWD1 2271 -4063
BTRC -1187 -2758
CANX -836 4736
CASP1 -1298 3173
CASP3 423 5016
CBL 1736 183
CCL2 2620 5111
CCND1 757 529
CD36 -582 -3838
CDC42 3308 754
CDKN1A -4927 5092
CFL1 -909 4720
CHUK 216 955
CLCF1 -2419 2301
CNN2 -4870 2117
COL1A2 -1712 -377
CREB1 2179 -4329
CRK 2145 2262
CRKL -91 4314
CRLF1 42 1779
CSF1 -4242 4358
CTF1 -3242 -4624
CUL1 -3121 -1536
DUSP3 -5149 -5173
DUSP4 -3613 3013
DUSP6 -528 -1256
DUSP7 -3477 -3537
ELK1 -3862 -42
F13A1 -2059 3642
FBXW11 4385 4535
FGF2 751 -1095
FN1 35 4022
FOS 1865 5273
FOXO1 -432 1302
FOXO3 -42 -1131
FSCN1 1705 -932
FYN -2850 3685
GAB2 4053 2422
GRB2 -4050 4496
GSTO1 -2055 -2038
HIF1A -1016 5007
HMGB1 -2199 -1662
HMOX1 -2843 5071
HNRNPA2B1 3693 -2053
HNRNPF 4978 4644
HSP90AA1 3656 5261
HSP90B1 460 4944
HSPA8 3674 5088
HSPA9 2342 -1431
ICAM1 1056 4172
IKBKB -4093 578
IL10RB 1239 3244
IL11RA -5610 -2978
IL13RA1 -1847 4516
IL15 -2409 -2685
IL16 -1613 -1365
IL17RA 219 4833
IL17RC -4271 1044
IL17RE -1865 -4593
IL18BP 292 2178
IL1R1 -3018 3910
IL1RAP 627 3712
IL20RB -159 -902
IL2RG -1943 3730
IL33 1864 3608
IL34 3060 -1540
IL4R -3335 4935
IL6R -5515 3267
IL6ST 3055 -2364
INPP5D -2433 4327
INPPL1 -5220 -4249
IRAK1 -4351 -480
IRAK2 -4255 3633
IRAK3 95 1688
IRAK4 -569 1975
IRF4 -1166 2585
IRS1 -5550 -5121
IRS2 3384 2684
ITGAM -2633 5045
ITGAX -896 3851
ITGB1 956 4614
ITGB2 -107 4993
JAK1 -1869 4228
JAK2 -2569 -5057
JUN 2469 5225
JUNB -2593 5221
LAMA5 -5584 -2744
LIFR -994 -4795
LMNB1 3392 2947
LYN 785 3984
MAOA -96 3927
MAP2K1 -506 -2643
MAP2K3 -4716 3039
MAP2K4 8 -3251
MAP2K6 1456 -4876
MAP2K7 794 -3887
MAP3K3 2825 757
MAP3K7 2142 -4056
MAP3K8 344 4159
MAPK1 1988 -648
MAPK10 -3504 -1859
MAPK11 -3385 -333
MAPK14 -1562 -1635
MAPK3 -1024 3725
MAPK7 -729 3565
MAPK8 457 1106
MAPK9 -3854 -3511
MAPKAPK2 -2489 -645
MAPKAPK3 -4795 -3142
MCL1 2837 4826
MEF2A -5175 -4103
MEF2C -4610 -2794
MIF -2307 2943
MMP2 -692 -2003
MSN -3907 4668
MTAP -2515 -2196
MYC 3994 4886
MYD88 2726 4679
NDN 1146 1877
NFKB1 -4233 3315
NFKB2 -3926 3336
NFKBIA -4263 4096
NFKBIB 4450 3578
NKIRAS1 4369 -2967
NKIRAS2 -1369 2403
NOD1 -3886 -3144
NOD2 -4402 1776
OSMR 255 4589
P4HB -2525 4048
PAK2 1525 4805
PDCD4 2217 1037
PELI1 4489 4759
PELI2 3371 -1012
PELI3 -4396 795
PIK3CA 365 2811
PIK3CB 2760 4994
PIK3CD -4322 -4161
PIK3R1 2896 -3147
PIK3R3 3188 577
PIM1 -228 4294
PITPNA -2450 -694
POU2F1 3019 -3333
PPIA -4031 4697
PPP2CA 4482 3008
PPP2CB 2458 4129
PPP2R1A -4013 -696
PPP2R1B 3028 4619
PPP2R5D -3449 -2058
PRKACA -4691 -1606
PSMA1 2820 3328
PSMA3 3434 -4
PSMA4 769 958
PSMA6 2199 -1044
PSMA7 -2980 976
PSMB1 954 2628
PSMB10 -1800 2907
PSMB2 618 2471
PSMB4 -235 2096
PSMB5 -4113 -606
PSMB6 -793 914
PSMB7 -831 -1453
PSMB8 -675 2066
PSMB9 -1611 -2973
PSMC1 449 -336
PSMC2 -1311 3241
PSMC3 -2439 -369
PSMC4 2724 1416
PSMC5 1212 -1123
PSMC6 -2520 3423
PSMD1 2619 -1191
PSMD10 -1227 525
PSMD11 995 5183
PSMD12 3831 536
PSMD13 821 1665
PSMD14 -635 3816
PSMD2 -713 -555
PSMD3 -3343 2226
PSMD4 -214 2558
PSMD5 1807 3558
PSMD6 3537 -2207
PSMD7 -2329 1233
PSMD8 -3171 4626
PSMD9 4204 -970
PSME1 -2771 3350
PSME2 -4085 3584
PSME3 3333 3379
PSME4 1960 -4574
PSMF1 683 -1480
PTK2B -2461 3862
PTPN11 -1575 -666
PTPN12 4141 5021
PTPN13 4200 -863
PTPN14 1287 -3965
PTPN18 -4024 2425
PTPN2 4314 4306
PTPN23 1152 5065
PTPN4 -1408 3737
PTPN6 -931 4799
PTPN9 -1215 2535
RALA -1368 504
RAP1B 4479 4565
RAPGEF1 -3992 3326
RBX1 -733 -968
RELA 1783 4531
RHOU -4229 -325
RIPK2 3609 4837
RORA -5056 -2699
RORC -5248 -4317
RPS27A 783 1840
RPS6KA1 -1481 -46
RPS6KA2 -4748 -5153
RPS6KA3 952 410
RPS6KA5 51 -5295
S1PR1 2689 1552
SDC1 -2046 212
SHC1 3976 3605
SIGIRR -452 -1704
SKP1 2028 -2504
SMAD3 -3794 -5343
SMARCA4 -3874 -1402
SNRPA1 4117 4600
SOCS1 199 4033
SOCS3 -283 5103
SOCS5 4145 1886
SOD1 157 807
SOD2 -1568 -3943
SOS1 -1962 -1007
SOS2 -563 -3782
SQSTM1 -3803 3545
STAT1 236 -1738
STAT2 -2601 280
STAT3 -3885 5061
STAT5A -4125 -4573
STAT5B -5022 -5306
STAT6 -5317 -1263
STX1A -411 1613
STX3 4376 -2465
STX4 -2347 78
TAB1 -4874 -4753
TAB2 2791 681
TAB3 2116 4834
TALDO1 -2080 -766
TBK1 673 3485
TCP1 4480 1210
TEC 3728 2609
TGFB1 -3111 4943
TIMP1 -1317 5239
TNFRSF1A -4666 3362
TNFRSF1B -874 4595
TNIP2 -1370 3203
TOLLIP -256 1337
TP53 575 3751
TRAF6 3468 1207
TWIST1 2624 2962
TXLNA -3216 2707
TYK2 -3123 -50
UBC 2672 4480
UBE2N 2545 3996
VAMP2 -3293 1812
VAMP7 2376 -4569
VCAM1 2866 4713
VEGFA -4571 -5196
VIM -3027 4772
VRK3 464 -1371
YES1 -176 -2941
YWHAZ 2019 4495
ZEB1 -4223 -195



Axon guidance

Axon guidance
metric value
setSize 378
pMANOVA 4.45e-11
p.adjustMANOVA 1.66e-09
s.dist 0.192
s.human -0.103
s.mouse 0.162
p.human 0.000649
p.mouse 9.05e-08




Top 20 genes
Gene human mouse
ITGA5 -4752 5178
RHOC -4944 4715
ARHGAP35 -4960 4536
ST8SIA2 -5423 3963
LIMK1 -4857 4174
PLXNA2 -5392 3724
CLTB -4579 4267
GDNF -4043 4741
SCN5A -5309 3520
MSN -3907 4668
GRB2 -4050 4496
GIT1 -4208 4025
NCAM1 -3954 4132
ITGA9 -5247 3076
PLXNA3 -5112 3055
ACTG1 -3075 4986
MYL6 -3628 4190
RPL10 -3902 3841
PSMD8 -3171 4626
PSME2 -4085 3584

Click HERE to show all gene set members

All member genes
human mouse
ABL1 -4533 -3545
ABL2 4315 4927
ABLIM1 -4649 2025
ABLIM2 -5452 -4200
ABLIM3 -5094 -4780
ACTB 940 4977
ACTG1 -3075 4986
ACTR2 3547 3933
ACTR3 1376 5136
ADAM10 -1509 -1025
AGAP2 -3629 2373
AGRN -4903 -2954
ALCAM 3531 4633
ANK1 -5583 -3806
ANK2 -4297 -4989
ANK3 1331 -4389
AP2A1 -3632 -420
AP2A2 -1058 5063
AP2B1 -1157 2251
AP2M1 -2746 3372
AP2S1 1777 1981
APH1A 204 -174
APH1B 3428 -1780
ARHGAP35 -4960 4536
ARHGAP39 -3062 1767
ARHGEF11 -1199 -2184
ARHGEF12 2630 3657
ARHGEF28 -2642 -552
ARHGEF7 -3605 1792
ARPC1A -120 2648
ARPC1B 669 4856
ARPC2 1357 4617
ARPC3 2873 3762
ARPC4 1698 2568
ARPC5 2295 4844
CACNA1C -762 -668
CACNA1H -5590 -3617
CACNA1S -5579 -4290
CACNB1 -5285 -5348
CACNB3 149 -3506
CAP1 2590 4328
CAP2 -5055 2009
CASC3 9 1880
CDC42 3308 754
CDK5 -1007 -793
CFL1 -909 4720
CLASP1 -3713 1181
CLASP2 2507 -309
CLTA 1218 1668
CLTB -4579 4267
CLTC 2268 -2802
CNTNAP1 -760 -2225
COL4A1 -4755 696
COL4A2 -5035 869
COL4A3 -3831 -4888
COL4A4 -3022 -3981
COL4A5 -4320 -3467
COL6A1 -1945 2037
COL6A2 -1836 2368
COL6A3 -119 2674
COL6A6 -2138 -3974
CREB1 2179 -4329
CSNK2A1 1796 -1733
CSNK2A2 2123 1393
CSNK2B 1917 -296
CUL2 4097 -3317
CXCL12 -4998 -359
DAG1 -5236 2687
DLG1 -52 918
DLG3 -1567 -2178
DLG4 -1594 364
DNM1 -747 1193
DNM2 -1149 2166
DNM3 4865 -1268
DOCK1 -226 -41
DOK1 -1380 -974
DOK4 2391 -1860
DOK5 -3981 3669
DPYSL2 -572 4116
DPYSL3 -801 3885
DPYSL5 -4934 2050
EFNB1 -2053 3790
EFNB2 4782 1555
EFNB3 -577 637
EGFR 424 1475
EIF4A3 4491 3824
EIF4G1 -2988 -4223
ENAH 4332 5242
EPHA2 -3029 -578
EPHA3 1472 -2138
EPHA4 -3528 207
EPHA7 2741 2897
EPHB1 -3669 -223
EPHB2 -3231 2001
EPHB3 -5580 -1737
EPHB4 606 3837
EPHB6 -1676 -58
ERBB2 -5511 673
ETF1 3946 4969
EVL -3566 2476
EZR -2209 4498
FARP2 -1333 -3397
FAU 2272 4115
FES 559 4512
FGFR1 -1499 -3421
FLRT3 4144 4201
FRS2 4678 761
FYN -2850 3685
GAB1 -1853 -2427
GAB2 4053 2422
GDNF -4043 4741
GFRA1 -4438 -2997
GIT1 -4208 4025
GPC1 -5269 -2966
GRB10 -1615 561
GRB2 -4050 4496
GSK3B 897 3200
GSPT1 1495 -2535
HFE2 -5332 -5168
HRAS -4545 -3997
HSP90AA1 3656 5261
HSP90AB1 -639 4629
HSPA8 3674 5088
IRS2 3384 2684
ITGA1 1757 -4136
ITGA10 -1878 -986
ITGA5 -4752 5178
ITGA9 -5247 3076
ITGAV -819 50
ITGB1 956 4614
ITGB3 -488 4915
ITSN1 524 -4884
KALRN -5340 228
KRAS 3546 4454
L1CAM 945 2245
LAMB1 -457 -387
LAMC1 -3224 2526
LDB1 -5369 -2642
LIMK1 -4857 4174
LIMK2 -5357 -3206
LYN 785 3984
LYPLA2 -3796 1864
MAGOH 4561 4010
MAGOHB 2239 2185
MAP2K1 -506 -2643
MAP2K2 -3813 -1797
MAPK1 1988 -648
MAPK11 -3385 -333
MAPK12 -5264 644
MAPK14 -1562 -1635
MAPK3 -1024 3725
MAPK7 -729 3565
MAPK8 457 1106
MET -3529 2929
MMP2 -692 -2003
MSN -3907 4668
MYH10 50 4851
MYH14 -3853 -3913
MYH9 -1879 4194
MYL12A 84 5226
MYL12B 1563 1984
MYL6 -3628 4190
MYL9 -4777 11
MYO10 1381 294
MYO9B -1901 4055
NCAM1 -3954 4132
NCBP1 -1736 4182
NCBP2 4188 264
NCK1 3718 1288
NCK2 -953 -2223
NCSTN -2504 1262
NEO1 -1978 3295
NFASC -2394 602
NRAS 4354 69
NRP1 -112 -4259
NRP2 2152 -2962
NTN1 -3499 244
NTN4 -1261 -948
NUMB 2961 3421
PAK1 -5419 -4885
PAK2 1525 4805
PAK4 -1756 4911
PDLIM7 -5046 -1156
PFN1 467 1712
PFN2 -4209 -3534
PIK3CA 365 2811
PIK3CB 2760 4994
PIK3CD -4322 -4161
PIK3R1 2896 -3147
PIK3R3 3188 577
PIP5K1C -1917 390
PITPNA -2450 -694
PLCG1 -3955 -4939
PLXNA1 -4487 -539
PLXNA2 -5392 3724
PLXNA3 -5112 3055
PLXNA4 -319 -842
PLXNB1 -5451 -1100
PLXNB3 -4041 -4305
PLXNC1 3270 1358
PLXND1 -4476 -3331
PPP3CB -3435 -5065
PRKACA -4691 -1606
PRKACB -2659 -1546
PRKAR2A -2664 -655
PRKCA -2938 -2924
PRKCQ -5095 -4882
PRNP 2908 4942
PSEN1 2070 2061
PSEN2 -5371 -1458
PSENEN -2638 482
PSMA1 2820 3328
PSMA3 3434 -4
PSMA4 769 958
PSMA6 2199 -1044
PSMA7 -2980 976
PSMB1 954 2628
PSMB10 -1800 2907
PSMB2 618 2471
PSMB4 -235 2096
PSMB5 -4113 -606
PSMB6 -793 914
PSMB7 -831 -1453
PSMB8 -675 2066
PSMB9 -1611 -2973
PSMC1 449 -336
PSMC2 -1311 3241
PSMC3 -2439 -369
PSMC4 2724 1416
PSMC5 1212 -1123
PSMC6 -2520 3423
PSMD1 2619 -1191
PSMD10 -1227 525
PSMD11 995 5183
PSMD12 3831 536
PSMD13 821 1665
PSMD14 -635 3816
PSMD2 -713 -555
PSMD3 -3343 2226
PSMD4 -214 2558
PSMD5 1807 3558
PSMD6 3537 -2207
PSMD7 -2329 1233
PSMD8 -3171 4626
PSMD9 4204 -970
PSME1 -2771 3350
PSME2 -4085 3584
PSME3 3333 3379
PSME4 1960 -4574
PSMF1 683 -1480
PTK2 -2497 -1508
PTPN11 -1575 -666
PTPRA -402 3653
RAC1 2525 1457
RANBP9 4005 219
RAP1GAP -894 -3461
RASA1 -612 -183
RBX1 -733 -968
RDX -562 -4953
RELN 3729 1663
RGMA -661 -293
RGMB -413 -227
RHOA 539 4193
RHOB 4609 5128
RHOC -4944 4715
RND1 3883 5266
RNPS1 681 -379
ROBO1 3700 764
ROBO2 -3259 -3691
ROCK1 4876 -54
ROCK2 2205 314
RPL10 -3902 3841
RPL11 -2249 2690
RPL14 433 1505
RPL18 -1782 3926
RPL18A -2969 1546
RPL19 -502 2402
RPL22 1231 -695
RPL22L1 3380 4103
RPL23 -115 2472
RPL26 1047 3247
RPL28 -391 2871
RPL3 -786 4892
RPL30 286 2070
RPL31 -595 4273
RPL32 -367 2766
RPL34 1447 1856
RPL35A 812 1955
RPL36A 1261 2266
RPL37 -715 2388
RPL37A -1043 2280
RPL38 231 3306
RPL3L -5212 -3395
RPL4 -522 1026
RPL5 1206 4486
RPL7 1440 1916
RPL8 -2775 2474
RPLP2 -2469 2383
RPS11 -1582 3395
RPS12 -318 3958
RPS13 1131 3118
RPS14 -1412 1322
RPS15 -1799 1989
RPS15A -704 2410
RPS16 -1828 3864
RPS18 -974 2916
RPS19 -2045 2954
RPS20 -1844 4785
RPS21 -1536 707
RPS23 -68 1922
RPS24 256 1742
RPS26 -282 2982
RPS27A 783 1840
RPS27L -616 298
RPS29 -1140 2499
RPS3 -544 3102
RPS4X 83 1892
RPS5 -1577 2419
RPS6 -245 3549
RPS6KA1 -1481 -46
RPS6KA2 -4748 -5153
RPS6KA3 952 410
RPS6KA4 -1201 1752
RPS6KA5 51 -5295
RPS8 -1593 2271
RPS9 -1107 1580
RRAS -4504 1351
SCN1B -4899 -5314
SCN2A 544 316
SCN2B -4268 -1921
SCN3A 2439 4422
SCN3B -3892 2980
SCN4A -5601 -5087
SCN5A -5309 3520
SDC2 1756 4483
SDCBP 4377 4839
SEMA3A 2682 1065
SEMA4A 796 3229
SEMA4D -5491 -4922
SEMA5A 485 -2610
SEMA6A 3579 -3659
SEMA6D -3707 -3013
SEMA7A -768 4609
SH3KBP1 1014 -3709
SHANK3 -2640 -2199
SHC1 3976 3605
SIAH1 5006 1408
SIAH2 -1998 5216
SLIT1 -2284 179
SLIT3 -271 1547
SOS1 -1962 -1007
SOS2 -563 -3782
SPTAN1 -2425 -1976
SPTB -5499 -3499
SPTBN1 -2919 -3387
SRC -3910 1378
SRGAP1 938 747
SRGAP3 -3043 -1274
ST8SIA2 -5423 3963
ST8SIA4 3236 -3584
TIAM1 2024 403
TLN1 -3918 2975
TRIO 1163 -2925
TRPC1 1744 -577
UBC 2672 4480
UNC5A -775 -2406
UNC5B -1122 -4255
UPF2 3566 -3399
UPF3A -2545 842
UPF3B 1586 -4316
USP33 2501 -3073
VASP -142 366
VAV2 -4959 -899
VAV3 187 -1063
VLDLR -4564 -5322
WASL 2683 3268
YES1 -176 -2941
ZSWIM8 -1026 547



Neutrophil degranulation

Neutrophil degranulation
metric value
setSize 292
pMANOVA 1.03e-10
p.adjustMANOVA 3.71e-09
s.dist 0.219
s.human -0.0607
s.mouse 0.211
p.human 0.0765
p.mouse 7.43e-10




Top 20 genes
Gene human mouse
SERPINB6 -5411 4903
PFKL -4966 4932
SIRPA -5627 4222
VCL -4538 5034
ANXA2 -4123 5025
PPIA -4031 4697
ALDH3B1 -4529 4142
GALNS -3960 4545
CYB5R3 -5395 3330
CKAP4 -3818 4639
AMPD3 -4286 4079
PRDX6 -3481 4973
VAT1 -4095 4223
ASAH1 -3414 5051
GYG1 -3875 4435
TMBIM1 -4812 3552
DOK3 -5498 3093
TCIRG1 -3600 4552
S100A11 -3518 4650
CSTB -3426 4748

Click HERE to show all gene set members

All member genes
human mouse
ACLY -2628.0 3492.0
ACTR10 1853.0 897.0
ACTR1B -4206.0 3803.0
ACTR2 3547.0 3933.0
ADAM10 -1509.0 -1025.0
ADAM8 -2592.0 5107.0
AGA 1618.0 -4995.0
AGL -4967.0 -5094.0
AGPAT2 -4979.0 -2002.0
ALAD -3855.0 -3630.0
ALDH3B1 -4529.0 4142.0
ALDOA -5575.0 -3482.0
ALDOC 1379.0 4707.0
AMPD3 -4286.0 4079.0
ANO6 -4134.0 2564.0
ANPEP -215.0 -634.0
ANXA2 -4123.0 5025.0
AP1M1 3732.0 1437.0
AP2A2 -1058.0 5063.0
APAF1 -3469.0 2921.0
APEH -3390.0 -1366.0
APRT -3384.0 -51.0
ARHGAP9 -2941.0 2431.0
ARL8A -4586.0 3346.0
ARMC8 -194.0 -4059.0
ARPC5 2295.0 4844.0
ARSA -3312.0 1530.0
ARSB -1001.0 2832.0
ASAH1 -3414.0 5051.0
ATAD3B 1907.0 -4078.5
ATG7 -1364.0 1374.0
ATP11A -1843.0 -4608.0
ATP11B 4841.0 -2179.0
ATP6AP2 2114.0 5158.0
ATP6V0A1 -3809.0 1763.0
ATP6V1D 3269.0 -2868.0
ATP8A1 1830.0 -3788.0
B2M -731.0 1593.0
B4GALT1 -1314.0 2589.0
BRI3 -3525.0 -1234.0
C3 4311.0 1838.0
C6orf120 1881.0 2354.0
CAB39 2485.0 2704.0
CAND1 3370.0 4369.0
CANT1 511.0 1963.0
CAP1 2590.0 4328.0
CAPN1 -5166.0 -4425.0
CAT -4828.0 -4266.0
CCT2 3805.0 4207.0
CCT8 4149.0 3796.0
CD36 -582.0 -3838.0
CD44 837.0 4987.0
CD47 -2184.0 2680.0
CD55 220.0 -323.0
CD59 1637.0 -4378.0
CD63 -3297.0 4594.0
CDK13 4123.0 1830.0
CEP290 3352.0 -4522.0
CKAP4 -3818.0 4639.0
CMTM6 2331.0 4071.0
CNN2 -4870.0 2117.0
COMMD3 246.0 -1247.0
COMMD9 385.0 1630.0
COPB1 3916.0 4572.0
COTL1 -1553.0 5172.0
CPNE3 1228.0 -3452.0
CPPED1 -3625.0 -4900.0
CREG1 1430.0 -1124.0
CRISPLD2 -871.0 -3137.0
CSNK2B 1917.0 -296.0
CSTB -3426.0 4748.0
CTSA -3537.0 -2181.0
CTSB -1198.0 -795.0
CTSC 2720.0 2417.0
CTSD -4817.0 -4037.0
CTSH -3465.0 3123.0
CTSS -339.0 5084.0
CTSZ -3890.0 3389.0
CYB5R3 -5395.0 3330.0
CYBA -633.0 3083.0
CYBB -2550.0 3579.0
CYSTM1 -1304.0 1985.0
DBNL -2320.0 4579.0
DDOST 320.0 4699.0
DDX3X 4686.0 4170.0
DEGS1 -2228.0 3767.0
DERA 3823.0 1200.0
DGAT1 -2804.0 -1001.0
DIAPH1 3282.0 5032.0
DNAJC13 1888.0 -3638.0
DNAJC3 1950.0 1334.0
DNAJC5 -2830.0 1053.0
DNASE1L1 -5205.0 -5289.0
DOK3 -5498.0 3093.0
DPP7 -4199.0 2087.0
DSN1 2075.0 534.0
DYNC1H1 -1442.0 -2348.0
DYNC1LI1 2883.0 1316.0
DYNLL1 -1331.0 4245.0
DYNLT1 2579.0 1650.0
EEF1A1 -2150.0 2931.0
EEF2 -2853.0 -853.0
ENPP4 -1280.0 -3299.0
ERP44 2150.0 2698.0
FABP5 -338.0 -519.0
FAF2 3890.0 3211.0
FGL2 -1862.0 3038.0
FRK 194.0 -2049.0
FTH1 -1890.0 -127.0
FUCA1 111.0 1320.0
FUCA2 -2160.0 -4180.0
GAA -5001.0 -3369.0
GALNS -3960.0 4545.0
GCA 2461.0 -4105.0
GDI2 865.0 4849.0
GGH 3482.0 1046.0
GHDC -3542.0 -4089.0
GLA 3418.0 -1853.0
GLB1 -2244.0 924.0
GM2A -1169.0 2670.0
GNS 101.0 -979.0
GOLGA7 1185.0 2077.0
GPI -5210.0 -4132.0
GRN -4029.0 2537.0
GSDMD -2517.0 3392.0
GSN 72.0 -256.0
GUSB 1923.0 4153.0
GYG1 -3875.0 4435.0
HEXB 753.0 2379.0
HGSNAT -4600.0 -3529.0
HMGB1 -2199.0 -1662.0
HMOX2 -687.0 552.0
HSP90AA1 3656.0 5261.0
HSP90AB1 -639.0 4629.0
HSPA1A 4887.0 5277.5
HSPA1B 4676.0 5277.5
HSPA8 3674.0 5088.0
HUWE1 -673.0 -4013.0
HVCN1 -2318.0 -2383.0
IDH1 1160.0 -5189.0
IGF2R -2030.0 -1074.0
ILF2 4835.0 4254.0
IMPDH1 -827.0 2546.0
IMPDH2 822.0 1907.0
IQGAP1 -415.0 3217.0
IST1 3827.0 4131.0
ITGAM -2633.0 5045.0
ITGAV -819.0 50.0
ITGAX -896.0 3851.0
ITGB2 -107.0 4993.0
JUP 1723.0 4368.0
KCMF1 501.0 -1005.0
KCNAB2 -3198.0 5020.0
KPNB1 3619.0 3517.0
LAMP1 764.0 -2637.0
LAMP2 -2579.0 848.0
LAMTOR1 -800.0 -2671.0
LAMTOR2 -1715.0 -424.0
LAMTOR3 3134.0 3162.0
LGALS3 1062.0 4809.0
LPCAT1 -1659.0 2005.0
LTA4H 1584.0 4089.0
MAGT1 1192.0 -1341.0
MAN2B1 -3000.0 331.0
MANBA -1928.0 -2694.0
MAPK1 1988.0 -648.0
MAPK14 -1562.0 -1635.0
METTL7A -5605.0 -5247.0
MGST1 427.0 -2546.0
MIF -2307.0 2943.0
MLEC -3173.0 -5166.0
MME -3346.0 -3103.0
MOSPD2 3720.0 -2512.0
MVP -4506.0 2829.0
NBEAL2 -4727.0 -339.0
NCSTN -2504.0 1262.0
NDUFC2 34.0 -2430.0
NEU1 1863.0 4218.0
NFASC -2394.0 602.0
NFKB1 -4233.0 3315.0
NHLRC3 -3747.0 2370.0
NIT2 -1606.0 -943.0
NPC2 790.0 2258.0
NRAS 4354.0 69.0
ORMDL3 893.0 3912.0
OSTF1 2228.0 2902.0
PADI2 -5625.0 -4599.0
PAFAH1B2 3709.0 4387.0
PDAP1 -1236.0 1825.0
PDXK -4690.0 -834.0
PFKL -4966.0 4932.0
PGM1 -4270.0 -4493.0
PGM2 -561.0 3964.0
PGRMC1 -333.0 1308.0
PKM -4231.0 -4264.0
PLAU -548.0 1192.0
PLAUR -638.0 3744.0
PLD1 55.0 -779.0
PLEKHO2 -717.0 3402.0
PNP 5019.5 4586.0
PPIA -4031.0 4697.0
PPIE 2144.0 896.0
PRCP 970.0 870.0
PRDX4 132.0 2521.0
PRDX6 -3481.0 4973.0
PRKCD -4276.0 3377.0
PSAP -2247.0 -4040.0
PSEN1 2070.0 2061.0
PSMB1 954.0 2628.0
PSMB7 -831.0 -1453.0
PSMC2 -1311.0 3241.0
PSMC3 -2439.0 -369.0
PSMD1 2619.0 -1191.0
PSMD11 995.0 5183.0
PSMD12 3831.0 536.0
PSMD13 821.0 1665.0
PSMD14 -635.0 3816.0
PSMD2 -713.0 -555.0
PSMD3 -3343.0 2226.0
PSMD6 3537.0 -2207.0
PSMD7 -2329.0 1233.0
PTGES2 -2699.0 -3434.0
PTPN6 -931.0 4799.0
PTPRB -4654.0 -4596.0
PTPRJ 391.0 3748.0
PTX3 -1790.0 728.0
PYCARD -2810.0 4703.0
PYGB -4498.0 1915.0
PYGL -3546.0 4121.0
QPCT 250.0 4615.0
QSOX1 2045.0 2998.0
RAB10 -2646.0 -3853.0
RAB14 2341.0 -844.0
RAB18 4588.0 -4361.0
RAB24 -1792.0 -4677.0
RAB27A 169.0 1070.0
RAB31 -547.0 4084.0
RAB3A 75.0 -3951.0
RAB3D 3527.0 1980.0
RAB5B 584.0 -3464.0
RAB5C 2317.0 3393.0
RAB7A -383.0 1499.0
RAC1 2525.0 1457.0
RAP1A -689.0 3710.0
RAP1B 4479.0 4565.0
RAP2B 3971.0 4705.0
RAP2C -983.0 -2112.0
RHOA 539.0 4193.0
RHOG -1207.0 4926.0
RNASET2 -4153.0 1724.0
ROCK1 4876.0 -54.0
S100A11 -3518.0 4650.0
SCAMP1 -549.0 1634.0
SDCBP 4377.0 4839.0
SERPINB1 1882.0 5166.0
SERPINB6 -5411.0 4903.0
SIRPA -5627.0 4222.0
SLC15A4 -527.0 856.0
SLC2A3 5004.0 2971.5
SLC44A2 -5438.0 -4740.0
SNAP23 372.0 -209.0
SNAP29 -2698.0 1321.0
SPTAN1 -2425.0 -1976.0
SRP14 2888.0 -1495.0
STK10 -3246.0 1353.0
STK11IP -451.0 -2797.0
STOM 2424.0 4434.0
SURF4 1238.0 3721.0
SVIP 3363.0 -4988.0
SYNGR1 -4900.0 -5133.0
TCIRG1 -3600.0 4552.0
TIMP2 -1886.0 -738.0
TMBIM1 -4812.0 3552.0
TMC6 -4677.0 -1324.0
TMEM30A 2855.0 -2390.0
TMEM63A -4829.0 841.0
TNFAIP6 1870.0 3235.0
TNFRSF1B -874.0 4595.0
TOLLIP -256.0 1337.0
TOM1 -5386.0 -3241.0
TRAPPC1 368.0 -653.0
TSPAN14 -4941.0 -1469.0
TUBB -3118.0 5070.0
TUBB4B 430.0 4896.0
UBR4 2440.0 -3370.0
VAMP8 -2728.0 -3233.0
VAPA 2838.0 2906.0
VAT1 -4095.0 4223.0
VCL -4538.0 5034.0
XRCC5 4010.0 -2853.0
XRCC6 3225.0 -1241.0
YPEL5 4366.0 3599.0



Cardiac conduction

Cardiac conduction
metric value
setSize 63
pMANOVA 1.05e-10
p.adjustMANOVA 3.71e-09
s.dist 0.528
s.human -0.449
s.mouse -0.278
p.human 7.15e-10
p.mouse 0.00014




Top 20 genes
Gene human mouse
ATP1A2 -5569 -5156
DMPK -5518 -5197
SCN4A -5601 -5087
CACNB1 -5285 -5348
SCN1B -4899 -5314
ATP2A1 -5479 -4584
CAMK2A -5527 -4430
CACNG6 -5276 -4552
RYR1 -5289 -4536
CAMK2B -5497 -4230
ATP2B3 -4422 -5220
SLC8A3 -5477 -3886
NOS1 -4260 -4935
KCNJ12 -5368 -3855
KCNJ2 -4246 -4660
NPR2 -3578 -5044
KAT2B -3340 -5260
TRDN -3364 -5213
ABCC9 -3151 -5198
FGF11 -3896 -3735

Click HERE to show all gene set members

All member genes
human mouse
ABCC9 -3151 -5198
AHCYL1 -3386 988
AKAP9 -573 -5181
ASPH -3277 -2678
ATP1A1 -4096 4907
ATP1A2 -5569 -5156
ATP1A3 206 3822
ATP1B1 2576 -3091
ATP1B3 -598 3075
ATP2A1 -5479 -4584
ATP2A2 -2976 515
ATP2A3 -4467 1862
ATP2B1 2034 159
ATP2B3 -4422 -5220
ATP2B4 -2762 -68
CACNA1C -762 -668
CACNB1 -5285 -5348
CACNG6 -5276 -4552
CALM1 -4464 96
CAMK2A -5527 -4430
CAMK2B -5497 -4230
CAMK2D -2223 4137
CAMK2G -2097 -4962
DMPK -5518 -5197
FGF11 -3896 -3735
FGF13 -844 616
FXYD1 -2722 -3530
HIPK1 4147 3646
HIPK2 -4312 -2060
ITPR1 4903 -2230
ITPR2 1242 -3115
ITPR3 -3631 -3441
KAT2B -3340 -5260
KCNE4 -764 2481
KCNH2 -3531 -1483
KCNJ11 -5488 -2118
KCNJ12 -5368 -3855
KCNJ2 -4246 -4660
KCNK2 -480 -2148
KCNK6 -1417 2020
KCNQ1 -3887 564
NOS1 -4260 -4935
NPR2 -3578 -5044
ORAI2 936 811
PLN -2060 814
PRKACA -4691 -1606
RANGRF -4019 157
RYR1 -5289 -4536
RYR3 -2435 351
SCN1B -4899 -5314
SCN2A 544 316
SCN2B -4268 -1921
SCN3A 2439 4422
SCN3B -3892 2980
SCN4A -5601 -5087
SCN5A -5309 3520
SLC8A1 754 -3579
SLC8A3 -5477 -3886
SRI -4069 3480
STIM1 -3417 -2324
TRDN -3364 -5213
TRPC1 1744 -577
WWTR1 -2503 809



SRP-dependent cotranslational protein targeting to membrane

SRP-dependent cotranslational protein targeting to membrane
metric value
setSize 74
pMANOVA 1.6e-10
p.adjustMANOVA 5.47e-09
s.dist 0.462
s.human 0.0968
s.mouse 0.451
p.human 0.151
p.mouse 1.96e-11




Top 20 genes
Gene human mouse
SRP54 4760 3804
SRP19 4688 3252
SSR3 4112 3670
RPL22L1 3380 4103
SPCS3 3092 4126
TRAM1 3799 3312
SSR2 2578 4341
FAU 2272 4115
SEC61A1 1613 4608
SSR1 2031 3112
SEC11C 1866 3276
RPL5 1206 4486
SEC61G 2374 2218
RPS13 1131 3118
RPL26 1047 3247
SPCS2 2182 1426
RPL36A 1261 2266
RPL7 1440 1916
RPL34 1447 1856
RPL35A 812 1955

Click HERE to show all gene set members

All member genes
human mouse
DDOST 320 4699
FAU 2272 4115
RPL10 -3902 3841
RPL11 -2249 2690
RPL14 433 1505
RPL18 -1782 3926
RPL18A -2969 1546
RPL19 -502 2402
RPL22 1231 -695
RPL22L1 3380 4103
RPL23 -115 2472
RPL26 1047 3247
RPL28 -391 2871
RPL3 -786 4892
RPL30 286 2070
RPL31 -595 4273
RPL32 -367 2766
RPL34 1447 1856
RPL35A 812 1955
RPL36A 1261 2266
RPL37 -715 2388
RPL37A -1043 2280
RPL38 231 3306
RPL3L -5212 -3395
RPL4 -522 1026
RPL5 1206 4486
RPL7 1440 1916
RPL8 -2775 2474
RPLP2 -2469 2383
RPN1 768 1558
RPN2 497 3166
RPS11 -1582 3395
RPS12 -318 3958
RPS13 1131 3118
RPS14 -1412 1322
RPS15 -1799 1989
RPS15A -704 2410
RPS16 -1828 3864
RPS18 -974 2916
RPS19 -2045 2954
RPS20 -1844 4785
RPS21 -1536 707
RPS23 -68 1922
RPS24 256 1742
RPS26 -282 2982
RPS27A 783 1840
RPS27L -616 298
RPS29 -1140 2499
RPS3 -544 3102
RPS4X 83 1892
RPS5 -1577 2419
RPS6 -245 3549
RPS8 -1593 2271
RPS9 -1107 1580
SEC11A -665 4070
SEC11C 1866 3276
SEC61A1 1613 4608
SEC61A2 4702 -4234
SEC61G 2374 2218
SPCS1 2081 -1591
SPCS2 2182 1426
SPCS3 3092 4126
SRP14 2888 -1495
SRP19 4688 3252
SRP54 4760 3804
SRP68 -940 -1385
SRP72 4000 257
SRP9 2308 -144
SRPRB -1164 3243
SSR1 2031 3112
SSR2 2578 4341
SSR3 4112 3670
SSR4 -2063 1435
TRAM1 3799 3312



Metabolism of non-coding RNA

Metabolism of non-coding RNA
metric value
setSize 45
pMANOVA 2.2e-10
p.adjustMANOVA 7.14e-09
s.dist 0.604
s.human 0.556
s.mouse 0.236
p.human 1.1e-10
p.mouse 0.00624




Top 20 genes
Gene human mouse
NUP98 4235 5066.0
NUP54 4508 3831.0
SNRPD1 3996 4006.0
NUP205 4438 3588.0
SNRPG 3179 3615.0
GEMIN6 3429 3153.0
RAE1 4471 2389.0
DDX20 4951 2067.0
NUP43 4562 2216.0
NUP107 3232 2949.0
TGS1 4576 2059.0
SNRPF 3777 2400.0
NUP188 2117 3830.0
NUP153 4762 1533.0
SMN1 4028 1732.5
GEMIN7 2344 2332.0
SEH1L 1085 4263.0
NUP160 3998 1035.0
PHAX 4729 840.0
NUP35 4571 649.0

Click HERE to show all gene set members

All member genes
human mouse
AAAS -3476 1550.0
CLNS1A 155 632.0
DDX20 4951 2067.0
GEMIN2 3264 -1096.0
GEMIN5 4699 -3017.0
GEMIN6 3429 3153.0
GEMIN7 2344 2332.0
GEMIN8 94 982.0
NCBP1 -1736 4182.0
NCBP2 4188 264.0
NDC1 1273 -2350.0
NUP107 3232 2949.0
NUP133 889 -4048.0
NUP153 4762 1533.0
NUP155 4306 -2233.0
NUP160 3998 1035.0
NUP188 2117 3830.0
NUP205 4438 3588.0
NUP214 3124 665.0
NUP35 4571 649.0
NUP37 -327 192.0
NUP43 4562 2216.0
NUP54 4508 3831.0
NUP85 3181 -393.0
NUP88 1244 2212.0
NUP93 -1503 3903.0
NUP98 4235 5066.0
PHAX 4729 840.0
PRMT5 933 1373.0
RAE1 4471 2389.0
RANBP2 4470 -3848.0
SEC13 730 1702.0
SEH1L 1085 4263.0
SMN1 4028 1732.5
SNRPB 3761 35.0
SNRPD1 3996 4006.0
SNRPD2 2043 -304.0
SNRPD3 2384 -1603.0
SNRPE 3421 760.0
SNRPF 3777 2400.0
SNRPG 3179 3615.0
SNUPN 2836 588.0
TGS1 4576 2059.0
TPR 2984 -1026.0
WDR77 -799 1494.0



snRNP Assembly

snRNP Assembly
metric value
setSize 45
pMANOVA 2.2e-10
p.adjustMANOVA 7.14e-09
s.dist 0.604
s.human 0.556
s.mouse 0.236
p.human 1.1e-10
p.mouse 0.00624




Top 20 genes
Gene human mouse
NUP98 4235 5066.0
NUP54 4508 3831.0
SNRPD1 3996 4006.0
NUP205 4438 3588.0
SNRPG 3179 3615.0
GEMIN6 3429 3153.0
RAE1 4471 2389.0
DDX20 4951 2067.0
NUP43 4562 2216.0
NUP107 3232 2949.0
TGS1 4576 2059.0
SNRPF 3777 2400.0
NUP188 2117 3830.0
NUP153 4762 1533.0
SMN1 4028 1732.5
GEMIN7 2344 2332.0
SEH1L 1085 4263.0
NUP160 3998 1035.0
PHAX 4729 840.0
NUP35 4571 649.0

Click HERE to show all gene set members

All member genes
human mouse
AAAS -3476 1550.0
CLNS1A 155 632.0
DDX20 4951 2067.0
GEMIN2 3264 -1096.0
GEMIN5 4699 -3017.0
GEMIN6 3429 3153.0
GEMIN7 2344 2332.0
GEMIN8 94 982.0
NCBP1 -1736 4182.0
NCBP2 4188 264.0
NDC1 1273 -2350.0
NUP107 3232 2949.0
NUP133 889 -4048.0
NUP153 4762 1533.0
NUP155 4306 -2233.0
NUP160 3998 1035.0
NUP188 2117 3830.0
NUP205 4438 3588.0
NUP214 3124 665.0
NUP35 4571 649.0
NUP37 -327 192.0
NUP43 4562 2216.0
NUP54 4508 3831.0
NUP85 3181 -393.0
NUP88 1244 2212.0
NUP93 -1503 3903.0
NUP98 4235 5066.0
PHAX 4729 840.0
PRMT5 933 1373.0
RAE1 4471 2389.0
RANBP2 4470 -3848.0
SEC13 730 1702.0
SEH1L 1085 4263.0
SMN1 4028 1732.5
SNRPB 3761 35.0
SNRPD1 3996 4006.0
SNRPD2 2043 -304.0
SNRPD3 2384 -1603.0
SNRPE 3421 760.0
SNRPF 3777 2400.0
SNRPG 3179 3615.0
SNUPN 2836 588.0
TGS1 4576 2059.0
TPR 2984 -1026.0
WDR77 -799 1494.0



Developmental Biology

Developmental Biology
metric value
setSize 588
pMANOVA 2.95e-10
p.adjustMANOVA 9.33e-09
s.dist 0.15
s.human -0.0706
s.mouse 0.132
p.human 0.00397
p.mouse 6.77e-08




Top 20 genes
Gene human mouse
CDKN1A -4927 5092
MYOD1 -5557 4473
ITGA5 -4752 5178
NAB2 -5323 4419
RHOC -4944 4715
ARHGAP35 -4960 4536
ST8SIA2 -5423 3963
SREBF2 -4703 4517
LIMK1 -4857 4174
PLXNA2 -5392 3724
STAT3 -3885 5061
CLTB -4579 4267
GDNF -4043 4741
EGR2 -3746 5076
SCN5A -5309 3520
KAZN -5114 3616
MSN -3907 4668
GRB2 -4050 4496
IL6R -5515 3267
MYOG -3660 4917

Click HERE to show all gene set members

All member genes
human mouse
ABL1 -4533 -3545
ABL2 4315 4927
ABLIM1 -4649 2025
ABLIM2 -5452 -4200
ABLIM3 -5094 -4780
ACTB 940 4977
ACTG1 -3075 4986
ACTR2 3547 3933
ACTR3 1376 5136
ACVR1B -1186 -5231
ACVR2A 3368 -787
ACVR2B -3415 -3382
ADAM10 -1509 -1025
ADAM11 2303 -38
ADAM22 -3821 -3730
ADAM23 -3602 -587
AGAP2 -3629 2373
AGRN -4903 -2954
AJUBA -4112 -892
AKT1 -4954 342
AKT2 -4057 -4450
AKT3 1343 -320
ALCAM 3531 4633
ANGPTL4 -739 2496
ANK1 -5583 -3806
ANK2 -4297 -4989
ANK3 1331 -4389
AP2A1 -3632 -420
AP2A2 -1058 5063
AP2B1 -1157 2251
AP2M1 -2746 3372
AP2S1 1777 1981
APH1A 204 -174
APH1B 3428 -1780
ARHGAP35 -4960 4536
ARHGAP39 -3062 1767
ARHGEF11 -1199 -2184
ARHGEF12 2630 3657
ARHGEF28 -2642 -552
ARHGEF7 -3605 1792
ARPC1A -120 2648
ARPC1B 669 4856
ARPC2 1357 4617
ARPC3 2873 3762
ARPC4 1698 2568
ARPC5 2295 4844
ASH2L -45 -3813
BNIP2 4068 -310
BOC -3568 -182
CACNA1C -762 -668
CACNA1H -5590 -3617
CACNA1S -5579 -4290
CACNB1 -5285 -5348
CACNB3 149 -3506
CAP1 2590 4328
CAP2 -5055 2009
CAPN1 -5166 -4425
CAPNS1 -1346 1750
CARM1 -4331 -4868
CASC3 9 1880
CBFB 3786 -4544
CCNC 4650 3537
CCND3 786 1371
CD36 -582 -3838
CDC42 3308 754
CDH15 -5540 -837
CDH2 608 -270
CDH4 -4535 -5351
CDK19 3157 -3958
CDK2 849 2686
CDK4 703 3417
CDK5 -1007 -793
CDK8 623 -1722
CDKN1A -4927 5092
CDON 4423 -1345
CEBPA -1649 5139
CEBPB -4699 1850
CFL1 -909 4720
CHD9 3127 -1910
CLASP1 -3713 1181
CLASP2 2507 -309
CLTA 1218 1668
CLTB -4579 4267
CLTC 2268 -2802
CNOT6 1509 2491
CNTNAP1 -760 -2225
COL4A1 -4755 696
COL4A2 -5035 869
COL4A3 -3831 -4888
COL4A4 -3022 -3981
COL4A5 -4320 -3467
COL6A1 -1945 2037
COL6A2 -1836 2368
COL6A3 -119 2674
COL6A6 -2138 -3974
CREB1 2179 -4329
CREBBP 1506 3139
CSNK2A1 1796 -1733
CSNK2A2 2123 1393
CSNK2B 1917 -296
CTCF 3507 -3224
CTNNA1 -2198 4004
CTNNB1 1714 -780
CUL2 4097 -3317
CXCL12 -4998 -359
CYP51A1 -1716 5047
DAG1 -5236 2687
DEK 2056 4641
DLG1 -52 918
DLG3 -1567 -2178
DLG4 -1594 364
DNM1 -747 1193
DNM2 -1149 2166
DNM3 4865 -1268
DOCK1 -226 -41
DOK1 -1380 -974
DOK4 2391 -1860
DOK5 -3981 3669
DPYSL2 -572 4116
DPYSL3 -801 3885
DPYSL5 -4934 2050
DRAP1 -2364 -1060
DRP2 -4004 511
E2F1 -529 4663
EBF1 -105 198
EED 3304 3671
EFNB1 -2053 3790
EFNB2 4782 1555
EFNB3 -577 637
EGFR 424 1475
EGR2 -3746 5076
EIF4A3 4491 3824
EIF4G1 -2988 -4223
ENAH 4332 5242
EP300 3403 -1622
EPAS1 21 -3171
EPHA2 -3029 -578
EPHA3 1472 -2138
EPHA4 -3528 207
EPHA7 2741 2897
EPHB1 -3669 -223
EPHB2 -3231 2001
EPHB3 -5580 -1737
EPHB4 606 3837
EPHB6 -1676 -58
ERBB2 -5511 673
ETF1 3946 4969
EVL -3566 2476
EZH2 4698 4740
EZR -2209 4498
FAM120B -1675 -3875
FARP2 -1333 -3397
FAU 2272 4115
FES 559 4512
FGF2 751 -1095
FGFR1 -1499 -3421
FLI1 -470 -2808
FLRT3 4144 4201
FOXO1 -432 1302
FOXO3 -42 -1131
FOXP1 906 2181
FRS2 4678 761
FURIN -4221 4117
FYN -2850 3685
GAB1 -1853 -2427
GAB2 4053 2422
GDNF -4043 4741
GFRA1 -4438 -2997
GIT1 -4208 4025
GPC1 -5269 -2966
GRB10 -1615 561
GRB2 -4050 4496
GSK3B 897 3200
GSPT1 1495 -2535
H2AFX 2356 5062
HDAC2 4386 -1101
HDAC3 -178 -4320
HELZ2 -2454 -322
HES1 1695 -1766
HFE2 -5332 -5168
HIF3A -3208 -1364
HMGCR 971 4631
HOXA3 -3040 -3174
HOXA4 -3530 -83
HOXB3 -116 -1829
HOXB4 3863 -1211
HOXC4 -2098 -2574
HRAS -4545 -3997
HSP90AA1 3656 5261
HSP90AB1 -639 4629
HSPA8 3674 5088
IL6R -5515 3267
IRS2 3384 2684
ITGA1 1757 -4136
ITGA10 -1878 -986
ITGA5 -4752 5178
ITGA9 -5247 3076
ITGAV -819 50
ITGB1 956 4614
ITGB3 -488 4915
ITSN1 524 -4884
JUN 2469 5225
JUP 1723 4368
KALRN -5340 228
KAT2A -5053 -1162
KAT2B -3340 -5260
KAZN -5114 3616
KDM6A 3809 1286
KLF4 3126 5024
KLF5 -2283 5186
KMT2A 4833 -157
KMT2C 4070 -3697
KMT2D -1176 -1807
KRAS 3546 4454
KRT10 2811 1949
KRT80 -2723 2227
L1CAM 945 2245
LAMA2 -3799 -762
LAMB1 -457 -387
LAMC1 -3224 2526
LDB1 -5369 -2642
LGI2 -2292 168
LGI4 -4303 825
LIMK1 -4857 4174
LIMK2 -5357 -3206
LYN 785 3984
LYPLA2 -3796 1864
MAFA -3291 -2751
MAFB 986 193
MAGOH 4561 4010
MAGOHB 2239 2185
MAML1 2770 4603
MAML2 2681 640
MAML3 -2079 -345
MAMLD1 -1668 1073
MAP2K1 -506 -2643
MAP2K2 -3813 -1797
MAP2K6 1456 -4876
MAPK1 1988 -648
MAPK11 -3385 -333
MAPK12 -5264 644
MAPK14 -1562 -1635
MAPK3 -1024 3725
MAPK7 -729 3565
MAPK8 457 1106
MBP -2415 1151
MED1 4772 -2976
MED10 4087 2651
MED11 -2050 1872
MED12 -2130 -2791
MED13 4601 4442
MED13L 2680 3613
MED14 2781 -4663
MED15 1233 4823
MED16 -2476 -4328
MED17 4255 676
MED18 3737 1006
MED19 3689 3433
MED20 3604 -3993
MED21 3526 2647
MED22 -2885 1923
MED23 3909 2513
MED24 -4786 -4086
MED25 2948 1925
MED26 4038 2036
MED27 1227 3689
MED28 1120 -610
MED29 3193 2240
MED30 2307 -28
MED31 4638 377
MED4 4026 4309
MED6 4813 2205
MED7 4316 2498
MED8 4163 -215
MED9 -227 2109
MEF2A -5175 -4103
MEF2C -4610 -2794
MEF2D -5348 -1189
MEIS1 1415 2729
MET -3529 2929
MMP2 -692 -2003
MSN -3907 4668
MYC 3994 4886
MYF5 -3108 -3732
MYF6 -3257 4744
MYH10 50 4851
MYH14 -3853 -3913
MYH9 -1879 4194
MYL12A 84 5226
MYL12B 1563 1984
MYL6 -3628 4190
MYL9 -4777 11
MYO10 1381 294
MYO9B -1901 4055
MYOD1 -5557 4473
MYOG -3660 4917
NAB1 -3099 2622
NAB2 -5323 4419
NCAM1 -3954 4132
NCBP1 -1736 4182
NCBP2 4188 264
NCK1 3718 1288
NCK2 -953 -2223
NCOA1 2628 -1167
NCOA2 146 -5050
NCOA3 4584 -321
NCOA6 -3402 -3336
NCOR1 2625 -3925
NCOR2 -5167 -1521
NCSTN -2504 1262
NEO1 -1978 3295
NFASC -2394 602
NFKB1 -4233 3315
NOTCH1 -5460 44
NR2F2 -1666 -1284
NR6A1 -2345 2302
NRAS 4354 69
NRP1 -112 -4259
NRP2 2152 -2962
NTN1 -3499 244
NTN4 -1261 -948
NUMB 2961 3421
PAK1 -5419 -4885
PAK2 1525 4805
PAK4 -1756 4911
PAXIP1 3409 1636
PBX1 -4735 -3394
PCSK6 -3791 258
PDLIM7 -5046 -1156
PERP 831 -2655
PFN1 467 1712
PFN2 -4209 -3534
PIAS2 2406 1628
PIK3CA 365 2811
PIK3CB 2760 4994
PIK3CD -4322 -4161
PIK3R1 2896 -3147
PIK3R3 3188 577
PIP5K1C -1917 390
PITPNA -2450 -694
PKNOX1 -2132 3650
PKP2 -5156 271
PKP4 -1228 1137
PLCG1 -3955 -4939
PLXNA1 -4487 -539
PLXNA2 -5392 3724
PLXNA3 -5112 3055
PLXNA4 -319 -842
PLXNB1 -5451 -1100
PLXNB3 -4041 -4305
PLXNC1 3270 1358
PLXND1 -4476 -3331
PML 3338 3449
PMP22 -1291 1645
POLR2A 3861 5046
POLR2B 4509 -4119
POLR2C 4529 -904
POLR2D 1669 2692
POLR2E -667 1599
POLR2G 89 5112
POLR2H -3927 3497
POLR2I -154 81
POLR2K 2480 -1584
POLR2L -4314 4110
PPARA -4997 -4570
PPARG -1621 -2269
PPARGC1A -4212 -5006
PPL -2270 30
PPP3CB -3435 -5065
PRKACA -4691 -1606
PRKACB -2659 -1546
PRKAR2A -2664 -655
PRKCA -2938 -2924
PRKCQ -5095 -4882
PRNP 2908 4942
PRX -2568 1483
PSEN1 2070 2061
PSEN2 -5371 -1458
PSENEN -2638 482
PSMA1 2820 3328
PSMA3 3434 -4
PSMA4 769 958
PSMA6 2199 -1044
PSMA7 -2980 976
PSMB1 954 2628
PSMB10 -1800 2907
PSMB2 618 2471
PSMB4 -235 2096
PSMB5 -4113 -606
PSMB6 -793 914
PSMB7 -831 -1453
PSMB8 -675 2066
PSMB9 -1611 -2973
PSMC1 449 -336
PSMC2 -1311 3241
PSMC3 -2439 -369
PSMC4 2724 1416
PSMC5 1212 -1123
PSMC6 -2520 3423
PSMD1 2619 -1191
PSMD10 -1227 525
PSMD11 995 5183
PSMD12 3831 536
PSMD13 821 1665
PSMD14 -635 3816
PSMD2 -713 -555
PSMD3 -3343 2226
PSMD4 -214 2558
PSMD5 1807 3558
PSMD6 3537 -2207
PSMD7 -2329 1233
PSMD8 -3171 4626
PSMD9 4204 -970
PSME1 -2771 3350
PSME2 -4085 3584
PSME3 3333 3379
PSME4 1960 -4574
PSMF1 683 -1480
PTK2 -2497 -1508
PTPN11 -1575 -666
PTPRA -402 3653
RAC1 2525 1457
RANBP9 4005 219
RAP1GAP -894 -3461
RARA -5250 2741
RARB -2995 -2000
RARG -4431 -4039
RASA1 -612 -183
RBBP4 1072 2469
RBBP5 4628 41
RBBP7 -924 -2291
RBPJ 305 4930
RBX1 -733 -968
RDX -562 -4953
RELA 1783 4531
RELN 3729 1663
RGMA -661 -293
RGMB -413 -227
RHOA 539 4193
RHOB 4609 5128
RHOC -4944 4715
RND1 3883 5266
RNPS1 681 -379
ROBO1 3700 764
ROBO2 -3259 -3691
ROCK1 4876 -54
ROCK2 2205 314
RPL10 -3902 3841
RPL11 -2249 2690
RPL14 433 1505
RPL18 -1782 3926
RPL18A -2969 1546
RPL19 -502 2402
RPL22 1231 -695
RPL22L1 3380 4103
RPL23 -115 2472
RPL26 1047 3247
RPL28 -391 2871
RPL3 -786 4892
RPL30 286 2070
RPL31 -595 4273
RPL32 -367 2766
RPL34 1447 1856
RPL35A 812 1955
RPL36A 1261 2266
RPL37 -715 2388
RPL37A -1043 2280
RPL38 231 3306
RPL3L -5212 -3395
RPL4 -522 1026
RPL5 1206 4486
RPL7 1440 1916
RPL8 -2775 2474
RPLP2 -2469 2383
RPS11 -1582 3395
RPS12 -318 3958
RPS13 1131 3118
RPS14 -1412 1322
RPS15 -1799 1989
RPS15A -704 2410
RPS16 -1828 3864
RPS18 -974 2916
RPS19 -2045 2954
RPS20 -1844 4785
RPS21 -1536 707
RPS23 -68 1922
RPS24 256 1742
RPS26 -282 2982
RPS27A 783 1840
RPS27L -616 298
RPS29 -1140 2499
RPS3 -544 3102
RPS4X 83 1892
RPS5 -1577 2419
RPS6 -245 3549
RPS6KA1 -1481 -46
RPS6KA2 -4748 -5153
RPS6KA3 952 410
RPS6KA4 -1201 1752
RPS6KA5 51 -5295
RPS8 -1593 2271
RPS9 -1107 1580
RQCD1 4265 347
RRAS -4504 1351
RUNX1 -2434 4962
RXRA -5519 -4191
SCN1B -4899 -5314
SCN2A 544 316
SCN2B -4268 -1921
SCN3A 2439 4422
SCN3B -3892 2980
SCN4A -5601 -5087
SCN5A -5309 3520
SDC2 1756 4483
SDCBP 4377 4839
SEMA3A 2682 1065
SEMA4A 796 3229
SEMA4D -5491 -4922
SEMA5A 485 -2610
SEMA6A 3579 -3659
SEMA6D -3707 -3013
SEMA7A -768 4609
SH3KBP1 1014 -3709
SHANK3 -2640 -2199
SHC1 3976 3605
SIAH1 5006 1408
SIAH2 -1998 5216
SLC2A4 -5524 -4293
SLIT1 -2284 179
SLIT3 -271 1547
SMAD2 1125 4898
SMAD3 -3794 -5343
SMAD4 2354 -52
SMARCA4 -3874 -1402
SMARCD3 -5399 -4597
SNW1 3618 4819
SOS1 -1962 -1007
SOS2 -563 -3782
SPAG9 -1939 -4313
SPTAN1 -2425 -1976
SPTB -5499 -3499
SPTBN1 -2919 -3387
SRC -3910 1378
SREBF1 -5230 594
SREBF2 -4703 4517
SRGAP1 938 747
SRGAP3 -3043 -1274
ST8SIA2 -5423 3963
ST8SIA4 3236 -3584
STAT3 -3885 5061
STX1A -411 1613
STX1B -468 -1328
SUZ12 3871 1927
TBL1XR1 1876 -2165
TCF12 1614 4124
TCF3 -2289 2184
TCF4 3907 -3970
TEAD1 -4292 -1880
TFDP1 -2245 -2659
TFDP2 4029 -5361
TGFB1 -3111 4943
TGS1 4576 2059
THRAP3 2457 661
TIAM1 2024 403
TLN1 -3918 2975
TRIO 1163 -2925
TRPC1 1744 -577
TSC22D1 -4450 3242
UBC 2672 4480
UNC5A -775 -2406
UNC5B -1122 -4255
UPF2 3566 -3399
UPF3A -2545 842
UPF3B 1586 -4316
USP33 2501 -3073
UTRN -3639 -3388
VASP -142 366
VAV2 -4959 -899
VAV3 187 -1063
VLDLR -4564 -5322
WASL 2683 3268
WDR5 -1608 1773
WWTR1 -2503 809
YAP1 -476 3863
YES1 -176 -2941
ZNF335 2976 2111
ZNF638 3977 -4583
ZSWIM8 -1026 547



Cellular responses to external stimuli

Cellular responses to external stimuli
metric value
setSize 410
pMANOVA 3.29e-10
p.adjustMANOVA 9.94e-09
s.dist 0.198
s.human 0.0499
s.mouse 0.191
p.human 0.0862
p.mouse 4.74e-11




Top 20 genes
Gene human mouse
HSPA1A 4887 5277.5
DNAJA1 4900 5100.0
HSPA1B 4676 5277.5
EZH2 4698 4740.0
SIRT1 4935 4484.0
DNAJB1 4185 5181.0
NUP98 4235 5066.0
HSPH1 4143 5073.0
HSPA13 4292 4891.0
CCNE1 4388 4753.0
HSP90AA1 3656 5261.0
UBE2S 4441 4268.0
HSPA8 3674 5088.0
ATP6V1C1 3521 5003.0
HSPA2 4948 3536.0
NUP54 4508 3831.0
DNAJC2 3424 4945.0
NUP205 4438 3588.0
CBX4 3208 4863.0
HSPA4 3842 3873.0

Click HERE to show all gene set members

All member genes
human mouse
AAAS -3476 1550.0
ACD -1324 68.0
ACTR10 1853 897.0
ACTR1A -4126 1651.0
AGO1 2453 -2704.0
AGO3 2529 -3975.0
AGO4 -3006 -3323.0
AJUBA -4112 -892.0
AKT1S1 271 -141.0
ANAPC1 572 -4087.0
ANAPC10 1974 2134.0
ANAPC11 -3265 -1751.0
ANAPC15 -3393 1787.0
ANAPC16 -3612 -1148.0
ANAPC2 -2185 -3532.0
ANAPC4 -720 -4834.0
ANAPC5 1284 -2104.0
ANAPC7 1595 2349.0
AR -4468 -5288.0
ARNT 3334 468.0
ASF1A 2517 2551.0
ASNS 2808 3601.0
ATF2 3130 1863.0
ATF3 522 5240.0
ATF4 -1161 5122.0
ATF5 -3260 1731.0
ATM 1449 -5067.0
ATOX1 646 433.0
ATP6V0B -3461 664.0
ATP6V0D1 -2256 4236.0
ATP6V0E1 1861 4262.0
ATP6V0E2 -1727 -2952.0
ATP6V1A 1633 729.0
ATP6V1B2 2299 4678.0
ATP6V1C1 3521 5003.0
ATP6V1D 3269 -2868.0
ATP6V1E1 3913 -407.0
ATP6V1F -3562 -2379.0
ATP6V1G2 1570 -473.0
ATP6V1H -57 4488.0
ATP7A 1448 -287.0
ATR 1983 -63.0
BAG1 -2339 -829.0
BAG2 -4046 3199.0
BAG3 -5162 5049.0
BAG4 4135 2734.0
BAG5 3025 943.0
BMI1 3349 2265.0
C12orf66 1895 3309.0
CABIN1 -2037 -282.0
CAMK2A -5527 -4430.0
CAMK2B -5497 -4230.0
CAMK2D -2223 4137.0
CAMK2G -2097 -4962.0
CAPZA2 -1777 -3734.0
CAPZB -3165 -2667.0
CAT -4828 -4266.0
CBX2 2360 -1671.0
CBX4 3208 4863.0
CBX6 -482 912.0
CBX8 -917 -541.0
CCNA2 3061 4292.0
CCNE1 4388 4753.0
CCNE2 4667 147.0
CCS -2218 -2785.0
CDC16 86 -1984.0
CDC23 3850 -1171.0
CDC26 2750 2457.0
CDC27 665 1230.0
CDK2 849 2686.0
CDK4 703 3417.0
CDK6 1090 3036.0
CDKN1A -4927 5092.0
CDKN1B -3284 -2450.0
CDKN2B -2827 2812.0
CDKN2C 3612 3091.0
CDKN2D 142 -1212.0
CEBPB -4699 1850.0
CEBPG -870 5.0
CHAC1 2903 -2432.0
CITED2 770 5188.0
CREBBP 1506 3139.0
CRYAB -2693 5268.0
CSRP1 -1093 2319.0
CUL2 4097 -3317.0
CYBA -633 3083.0
CYBB -2550 3579.0
DCTN1 -347 -2402.0
DCTN2 -3157 -448.0
DCTN3 -943 2888.0
DCTN4 613 242.0
DCTN5 2557 1793.0
DCTN6 1852 -2191.0
DDIT3 -1718 243.0
DEDD2 1209 -1847.0
DEPDC5 1253 -126.0
DNAJA1 4900 5100.0
DNAJA2 3865 1514.0
DNAJA4 -4430 5237.0
DNAJB1 4185 5181.0
DNAJB6 -3087 -2818.0
DNAJC2 3424 4945.0
DNAJC7 -1241 -3822.0
DYNC1H1 -1442 -2348.0
DYNC1I2 2591 -2971.0
DYNC1LI1 2883 1316.0
DYNC1LI2 1750 -1620.0
DYNLL1 -1331 4245.0
E2F1 -529 4663.0
E2F3 -4683 -1694.0
EED 3304 3671.0
EEF1A1 -2150 2931.0
EGLN1 3248 -3544.0
EGLN2 -533 -1745.0
EGLN3 -919 -951.0
EHMT1 -76 -2601.0
EHMT2 -520 -260.0
EIF2AK1 -824 -1145.0
EIF2AK4 -3765 -1462.0
EIF2S1 4274 3125.0
EIF2S2 3602 -364.0
EP300 3403 -1622.0
EP400 2478 -166.0
EPAS1 21 -3171.0
ERF 846 3448.0
ETS1 1408 -2404.0
ETS2 -3761 608.0
EZH2 4698 4740.0
FAU 2272 4115.0
FKBP4 1305 500.0
FKBP5 750 553.0
FLCN -2903 -4914.0
FNIP1 4049 -4243.0
FNIP2 -3302 3516.0
FOS 1865 5273.0
FZR1 -1244 3620.0
GPX1 -4411 3026.0
GPX3 -5081 -3870.0
GPX7 -5153 2186.0
GPX8 -458 1641.0
GRB10 -1615 561.0
GSK3B 897 3200.0
GSR -2148 1119.0
H2AFX 2356 5062.0
HDAC6 -4164 3925.0
HIF1A -1016 5007.0
HIF1AN -2114 -4148.0
HIF3A -3208 -1364.0
HIGD1A -2341 -1757.0
HIRA 832 686.0
HMGA1 598 5099.0
HSBP1 1620 74.0
HSF1 -5373 110.0
HSP90AA1 3656 5261.0
HSP90AB1 -639 4629.0
HSPA12A -3798 -3231.0
HSPA13 4292 4891.0
HSPA14 2830 1760.0
HSPA1A 4887 5277.5
HSPA1B 4676 5277.5
HSPA1L 519 5031.0
HSPA2 4948 3536.0
HSPA4 3842 3873.0
HSPA4L 4705 -62.0
HSPA5 2574 5200.0
HSPA8 3674 5088.0
HSPA9 2342 -1431.0
HSPB8 -5316 5197.0
HSPH1 4143 5073.0
ID1 -1307 3474.0
IGFBP7 505 1360.0
IMPACT -269 1150.0
ITFG2 454 1486.0
JUN 2469 5225.0
KAT5 447 3955.0
KDM6B -5026 -632.0
KPTN -4554 -3976.0
LAMTOR1 -800 -2671.0
LAMTOR2 -1715 -424.0
LAMTOR3 3134 3162.0
LAMTOR4 -2977 2289.0
LAMTOR5 636 -324.0
LIMD1 -1814 -3829.0
LMNB1 3392 2947.0
MAP2K3 -4716 3039.0
MAP2K4 8 -3251.0
MAP2K6 1456 -4876.0
MAP2K7 794 -3887.0
MAP3K5 1249 3914.0
MAP4K4 -4159 766.0
MAPK1 1988 -648.0
MAPK10 -3504 -1859.0
MAPK11 -3385 -333.0
MAPK14 -1562 -1635.0
MAPK3 -1024 3725.0
MAPK7 -729 3565.0
MAPK8 457 1106.0
MAPK9 -3854 -3511.0
MAPKAPK2 -2489 -645.0
MAPKAPK3 -4795 -3142.0
MDM2 3253 3321.0
MDM4 2051 -4809.0
MINK1 -3301 2408.0
MIOS 1011 634.0
MLST8 -3485 -2266.0
MOV10 -4127 1367.0
MRPL18 2996 -4236.0
MT1X -1521 5199.0
MT3 -499 -3503.0
MTF1 4744 930.0
MTOR -1191 -1922.0
NBN 1286 -1205.0
NDC1 1273 -2350.0
NFKB1 -4233 3315.0
NOX4 2301 1027.0
NPRL2 -2734 1186.0
NPRL3 -2240 -815.0
NR3C1 985 -4192.0
NR3C2 -1723 -18.0
NUDT2 -136 -2521.0
NUP107 3232 2949.0
NUP133 889 -4048.0
NUP153 4762 1533.0
NUP155 4306 -2233.0
NUP160 3998 1035.0
NUP188 2117 3830.0
NUP205 4438 3588.0
NUP214 3124 665.0
NUP35 4571 649.0
NUP37 -327 192.0
NUP43 4562 2216.0
NUP54 4508 3831.0
NUP85 3181 -393.0
NUP88 1244 2212.0
NUP93 -1503 3903.0
NUP98 4235 5066.0
P4HB -2525 4048.0
PHC1 456 -1955.0
PHC2 -3719 4976.0
PHC3 3141 -3012.0
POT1 3936 -4021.0
PPP1R15A 1886 5267.0
PRDX1 605 1340.0
PRDX2 -5293 -2557.0
PRDX3 -443 -3668.0
PRDX5 -3356 -1867.0
PRDX6 -3481 4973.0
PSMA1 2820 3328.0
PSMA3 3434 -4.0
PSMA4 769 958.0
PSMA6 2199 -1044.0
PSMA7 -2980 976.0
PSMB1 954 2628.0
PSMB10 -1800 2907.0
PSMB2 618 2471.0
PSMB4 -235 2096.0
PSMB5 -4113 -606.0
PSMB6 -793 914.0
PSMB7 -831 -1453.0
PSMB8 -675 2066.0
PSMB9 -1611 -2973.0
PSMC1 449 -336.0
PSMC2 -1311 3241.0
PSMC3 -2439 -369.0
PSMC4 2724 1416.0
PSMC5 1212 -1123.0
PSMC6 -2520 3423.0
PSMD1 2619 -1191.0
PSMD10 -1227 525.0
PSMD11 995 5183.0
PSMD12 3831 536.0
PSMD13 821 1665.0
PSMD14 -635 3816.0
PSMD2 -713 -555.0
PSMD3 -3343 2226.0
PSMD4 -214 2558.0
PSMD5 1807 3558.0
PSMD6 3537 -2207.0
PSMD7 -2329 1233.0
PSMD8 -3171 4626.0
PSMD9 4204 -970.0
PSME1 -2771 3350.0
PSME2 -4085 3584.0
PSME3 3333 3379.0
PSME4 1960 -4574.0
PSMF1 683 -1480.0
PTGES3 1328 3635.0
RAD50 306 -3473.0
RAE1 4471 2389.0
RANBP2 4470 -3848.0
RB1 -2449 1464.0
RBBP4 1072 2469.0
RBBP7 -924 -2291.0
RBX1 -733 -968.0
RELA 1783 4531.0
RHEB 172 2951.0
RING1 -1968 -125.0
RNF2 3038 4651.0
RPA1 -1837 -4231.0
RPA2 2889 -1373.0
RPA3 2702 -1706.0
RPL10 -3902 3841.0
RPL11 -2249 2690.0
RPL14 433 1505.0
RPL18 -1782 3926.0
RPL18A -2969 1546.0
RPL19 -502 2402.0
RPL22 1231 -695.0
RPL22L1 3380 4103.0
RPL23 -115 2472.0
RPL26 1047 3247.0
RPL28 -391 2871.0
RPL3 -786 4892.0
RPL30 286 2070.0
RPL31 -595 4273.0
RPL32 -367 2766.0
RPL34 1447 1856.0
RPL35A 812 1955.0
RPL36A 1261 2266.0
RPL37 -715 2388.0
RPL37A -1043 2280.0
RPL38 231 3306.0
RPL3L -5212 -3395.0
RPL4 -522 1026.0
RPL5 1206 4486.0
RPL7 1440 1916.0
RPL8 -2775 2474.0
RPLP2 -2469 2383.0
RPS11 -1582 3395.0
RPS12 -318 3958.0
RPS13 1131 3118.0
RPS14 -1412 1322.0
RPS15 -1799 1989.0
RPS15A -704 2410.0
RPS16 -1828 3864.0
RPS18 -974 2916.0
RPS19 -2045 2954.0
RPS19BP1 -1354 4256.0
RPS20 -1844 4785.0
RPS21 -1536 707.0
RPS23 -68 1922.0
RPS24 256 1742.0
RPS26 -282 2982.0
RPS27A 783 1840.0
RPS27L -616 298.0
RPS29 -1140 2499.0
RPS3 -544 3102.0
RPS4X 83 1892.0
RPS5 -1577 2419.0
RPS6 -245 3549.0
RPS6KA1 -1481 -46.0
RPS6KA2 -4748 -5153.0
RPS6KA3 952 410.0
RPS8 -1593 2271.0
RPS9 -1107 1580.0
RPTOR -4596 2076.0
RRAGA 2383 4477.0
RRAGB -366 -548.0
RRAGC 2091 945.0
RRAGD -4673 -5179.0
SCMH1 -5007 -1597.0
SEC13 730 1702.0
SEH1L 1085 4263.0
SERPINH1 -3526 3768.0
SESN1 -4227 3713.0
SESN2 -2604 5137.0
SH3BP4 -5382 5019.0
SIRT1 4935 4484.0
SLC38A9 969 -2953.0
SOD1 157 807.0
SOD2 -1568 -3943.0
SOD3 -1046 4449.0
SP1 1787 -1016.0
ST13 -123 3413.0
STAT3 -3885 5061.0
STIP1 2780 4885.0
SUZ12 3871 1927.0
SZT2 3003 -2529.0
TCIRG1 -3600 4552.0
TERF1 422 16.0
TERF2 -1834 1195.0
TERF2IP 4692 -1399.0
TFDP1 -2245 -2659.0
TFDP2 4029 -5361.0
TINF2 -1257 1757.0
TNFRSF21 -2507 -4518.0
TNIK 334 -2042.0
TNRC6A 3585 -573.0
TNRC6B 3118 -4527.0
TNRC6C -2020 -1918.0
TP53 575 3751.0
TPR 2984 -1026.0
TRIB3 -1004 3791.0
TXN 1855 4791.0
TXN2 -2838 641.0
TXNRD1 -2444 2445.0
TXNRD2 -4424 -3456.0
UBC 2672 4480.0
UBE2C 4949 463.0
UBE2D1 -1588 -4032.0
UBE2D2 -1986 3383.0
UBE2D3 1424 4934.0
UBE2E1 -1132 -479.0
UBE2S 4441 4268.0
UBN1 2086 3668.0
VEGFA -4571 -5196.0
WDR24 564 -3209.0
WDR59 -3369 -1580.0
WTIP -4938 -615.0
YWHAE 1394 -914.0



Transcription of the HIV genome

Transcription of the HIV genome
metric value
setSize 59
pMANOVA 3.31e-10
p.adjustMANOVA 9.94e-09
s.dist 0.535
s.human 0.436
s.mouse 0.31
p.human 7.27e-09
p.mouse 3.94e-05




Top 20 genes
Gene human mouse
TAF4B 4967 5209
GTF2F1 4999 4919
TAF7 4717 4909
GTF2B 4276 5124
GTF2A1 4730 4588
GTF2F2 4067 5069
POLR2A 3861 5046
TAF3 4294 4474
SUPT16H 3885 4363
TAF2 4591 3381
TAF5 4309 2830
TAF12 3100 3164
CTDP1 2071 4335
TAF13 4749 1567
SSRP1 1755 3948
RNGTT 4414 1057
SUPT5H 1321 3508
POLR2D 1669 2692
GTF2H1 3886 1058
GTF2E1 2188 1803

Click HERE to show all gene set members

All member genes
human mouse
CCNH 3825 -1657.0
CCNK 3139 154.0
CCNT1 4896 -1160.0
CCNT2 4381 -5015.0
CDK7 1571 -2032.0
CDK9 -1348 4462.0
CTDP1 2071 4335.0
ELL -3990 3019.0
ERCC2 824 2393.0
ERCC3 473 1570.0
GTF2A1 4730 4588.0
GTF2A2 4648 -1742.0
GTF2B 4276 5124.0
GTF2E1 2188 1803.0
GTF2E2 2041 120.0
GTF2F1 4999 4919.0
GTF2F2 4067 5069.0
GTF2H1 3886 1058.0
GTF2H2 4419 -2446.5
GTF2H3 -1925 467.0
GTF2H5 -878 -1711.0
MNAT1 830 -2433.0
NCBP1 -1736 4182.0
NCBP2 4188 264.0
NELFA 356 3929.0
NELFB -1196 2773.0
NELFCD 1896 -2294.0
NELFE -2178 3334.0
POLR2A 3861 5046.0
POLR2B 4509 -4119.0
POLR2C 4529 -904.0
POLR2D 1669 2692.0
POLR2E -667 1599.0
POLR2G 89 5112.0
POLR2H -3927 3497.0
POLR2I -154 81.0
POLR2K 2480 -1584.0
POLR2L -4314 4110.0
RNGTT 4414 1057.0
RNMT 4864 -807.0
SSRP1 1755 3948.0
SUPT16H 3885 4363.0
SUPT4H1 3648 -1203.0
SUPT5H 1321 3508.0
TAF1 1708 -350.0
TAF10 -273 2957.0
TAF11 2962 -484.0
TAF12 3100 3164.0
TAF13 4749 1567.0
TAF2 4591 3381.0
TAF3 4294 4474.0
TAF4 -1340 3063.0
TAF4B 4967 5209.0
TAF5 4309 2830.0
TAF6 -912 55.0
TAF7 4717 4909.0
TAF9B 1874 519.0
TBP 1137 2611.0
TCEA1 4037 647.0



Influenza Viral RNA Transcription and Replication

Influenza Viral RNA Transcription and Replication
metric value
setSize 91
pMANOVA 3.68e-10
p.adjustMANOVA 1.08e-08
s.dist 0.42
s.human 0.157
s.mouse 0.389
p.human 0.00998
p.mouse 1.44e-10




Top 20 genes
Gene human mouse
GTF2F1 4999 4919
NUP98 4235 5066
GTF2F2 4067 5069
POLR2A 3861 5046
HSP90AA1 3656 5261
NUP54 4508 3831
NUP205 4438 3588
RPL22L1 3380 4103
RAE1 4471 2389
NUP43 4562 2216
NUP107 3232 2949
FAU 2272 4115
NUP188 2117 3830
IPO5 1982 3806
NUP153 4762 1533
RPL5 1206 4486
SEH1L 1085 4263
POLR2D 1669 2692
NUP160 3998 1035
RPS13 1131 3118

Click HERE to show all gene set members

All member genes
human mouse
AAAS -3476 1550
DNAJC3 1950 1334
FAU 2272 4115
GRSF1 -3131 -4623
GTF2F1 4999 4919
GTF2F2 4067 5069
HSP90AA1 3656 5261
IPO5 1982 3806
NDC1 1273 -2350
NUP107 3232 2949
NUP133 889 -4048
NUP153 4762 1533
NUP155 4306 -2233
NUP160 3998 1035
NUP188 2117 3830
NUP205 4438 3588
NUP214 3124 665
NUP35 4571 649
NUP37 -327 192
NUP43 4562 2216
NUP54 4508 3831
NUP85 3181 -393
NUP88 1244 2212
NUP93 -1503 3903
NUP98 4235 5066
PARP1 -2423 -2631
POLR2A 3861 5046
POLR2B 4509 -4119
POLR2C 4529 -904
POLR2D 1669 2692
POLR2E -667 1599
POLR2G 89 5112
POLR2H -3927 3497
POLR2I -154 81
POLR2K 2480 -1584
POLR2L -4314 4110
RAE1 4471 2389
RANBP2 4470 -3848
RPL10 -3902 3841
RPL11 -2249 2690
RPL14 433 1505
RPL18 -1782 3926
RPL18A -2969 1546
RPL19 -502 2402
RPL22 1231 -695
RPL22L1 3380 4103
RPL23 -115 2472
RPL26 1047 3247
RPL28 -391 2871
RPL3 -786 4892
RPL30 286 2070
RPL31 -595 4273
RPL32 -367 2766
RPL34 1447 1856
RPL35A 812 1955
RPL36A 1261 2266
RPL37 -715 2388
RPL37A -1043 2280
RPL38 231 3306
RPL3L -5212 -3395
RPL4 -522 1026
RPL5 1206 4486
RPL7 1440 1916
RPL8 -2775 2474
RPLP2 -2469 2383
RPS11 -1582 3395
RPS12 -318 3958
RPS13 1131 3118
RPS14 -1412 1322
RPS15 -1799 1989
RPS15A -704 2410
RPS16 -1828 3864
RPS18 -974 2916
RPS19 -2045 2954
RPS20 -1844 4785
RPS21 -1536 707
RPS23 -68 1922
RPS24 256 1742
RPS26 -282 2982
RPS27A 783 1840
RPS27L -616 298
RPS29 -1140 2499
RPS3 -544 3102
RPS4X 83 1892
RPS5 -1577 2419
RPS6 -245 3549
RPS8 -1593 2271
RPS9 -1107 1580
SEC13 730 1702
SEH1L 1085 4263
TPR 2984 -1026



Cellular responses to stress

Cellular responses to stress
metric value
setSize 406
pMANOVA 4.76e-10
p.adjustMANOVA 1.36e-08
s.dist 0.197
s.human 0.049
s.mouse 0.19
p.human 0.0936
p.mouse 6.79e-11




Top 20 genes
Gene human mouse
HSPA1A 4887 5277.5
DNAJA1 4900 5100.0
HSPA1B 4676 5277.5
EZH2 4698 4740.0
SIRT1 4935 4484.0
DNAJB1 4185 5181.0
NUP98 4235 5066.0
HSPH1 4143 5073.0
HSPA13 4292 4891.0
CCNE1 4388 4753.0
HSP90AA1 3656 5261.0
UBE2S 4441 4268.0
HSPA8 3674 5088.0
ATP6V1C1 3521 5003.0
HSPA2 4948 3536.0
NUP54 4508 3831.0
DNAJC2 3424 4945.0
NUP205 4438 3588.0
CBX4 3208 4863.0
HSPA4 3842 3873.0

Click HERE to show all gene set members

All member genes
human mouse
AAAS -3476 1550.0
ACD -1324 68.0
ACTR10 1853 897.0
ACTR1A -4126 1651.0
AGO1 2453 -2704.0
AGO3 2529 -3975.0
AGO4 -3006 -3323.0
AJUBA -4112 -892.0
AKT1S1 271 -141.0
ANAPC1 572 -4087.0
ANAPC10 1974 2134.0
ANAPC11 -3265 -1751.0
ANAPC15 -3393 1787.0
ANAPC16 -3612 -1148.0
ANAPC2 -2185 -3532.0
ANAPC4 -720 -4834.0
ANAPC5 1284 -2104.0
ANAPC7 1595 2349.0
AR -4468 -5288.0
ARNT 3334 468.0
ASF1A 2517 2551.0
ASNS 2808 3601.0
ATF2 3130 1863.0
ATF3 522 5240.0
ATF4 -1161 5122.0
ATF5 -3260 1731.0
ATM 1449 -5067.0
ATOX1 646 433.0
ATP6V0B -3461 664.0
ATP6V0D1 -2256 4236.0
ATP6V0E1 1861 4262.0
ATP6V0E2 -1727 -2952.0
ATP6V1A 1633 729.0
ATP6V1B2 2299 4678.0
ATP6V1C1 3521 5003.0
ATP6V1D 3269 -2868.0
ATP6V1E1 3913 -407.0
ATP6V1F -3562 -2379.0
ATP6V1G2 1570 -473.0
ATP6V1H -57 4488.0
ATP7A 1448 -287.0
ATR 1983 -63.0
BAG1 -2339 -829.0
BAG2 -4046 3199.0
BAG3 -5162 5049.0
BAG4 4135 2734.0
BAG5 3025 943.0
BMI1 3349 2265.0
C12orf66 1895 3309.0
CABIN1 -2037 -282.0
CAMK2A -5527 -4430.0
CAMK2B -5497 -4230.0
CAMK2D -2223 4137.0
CAMK2G -2097 -4962.0
CAPZA2 -1777 -3734.0
CAPZB -3165 -2667.0
CAT -4828 -4266.0
CBX2 2360 -1671.0
CBX4 3208 4863.0
CBX6 -482 912.0
CBX8 -917 -541.0
CCNA2 3061 4292.0
CCNE1 4388 4753.0
CCNE2 4667 147.0
CCS -2218 -2785.0
CDC16 86 -1984.0
CDC23 3850 -1171.0
CDC26 2750 2457.0
CDC27 665 1230.0
CDK2 849 2686.0
CDK4 703 3417.0
CDK6 1090 3036.0
CDKN1A -4927 5092.0
CDKN1B -3284 -2450.0
CDKN2B -2827 2812.0
CDKN2C 3612 3091.0
CDKN2D 142 -1212.0
CEBPB -4699 1850.0
CEBPG -870 5.0
CHAC1 2903 -2432.0
CITED2 770 5188.0
CREBBP 1506 3139.0
CRYAB -2693 5268.0
CUL2 4097 -3317.0
CYBA -633 3083.0
CYBB -2550 3579.0
DCTN1 -347 -2402.0
DCTN2 -3157 -448.0
DCTN3 -943 2888.0
DCTN4 613 242.0
DCTN5 2557 1793.0
DCTN6 1852 -2191.0
DDIT3 -1718 243.0
DEDD2 1209 -1847.0
DEPDC5 1253 -126.0
DNAJA1 4900 5100.0
DNAJA2 3865 1514.0
DNAJA4 -4430 5237.0
DNAJB1 4185 5181.0
DNAJB6 -3087 -2818.0
DNAJC2 3424 4945.0
DNAJC7 -1241 -3822.0
DYNC1H1 -1442 -2348.0
DYNC1I2 2591 -2971.0
DYNC1LI1 2883 1316.0
DYNC1LI2 1750 -1620.0
DYNLL1 -1331 4245.0
E2F1 -529 4663.0
E2F3 -4683 -1694.0
EED 3304 3671.0
EEF1A1 -2150 2931.0
EGLN1 3248 -3544.0
EGLN2 -533 -1745.0
EGLN3 -919 -951.0
EHMT1 -76 -2601.0
EHMT2 -520 -260.0
EIF2AK1 -824 -1145.0
EIF2AK4 -3765 -1462.0
EIF2S1 4274 3125.0
EIF2S2 3602 -364.0
EP300 3403 -1622.0
EP400 2478 -166.0
EPAS1 21 -3171.0
ERF 846 3448.0
ETS1 1408 -2404.0
ETS2 -3761 608.0
EZH2 4698 4740.0
FAU 2272 4115.0
FKBP4 1305 500.0
FKBP5 750 553.0
FLCN -2903 -4914.0
FNIP1 4049 -4243.0
FNIP2 -3302 3516.0
FOS 1865 5273.0
FZR1 -1244 3620.0
GPX1 -4411 3026.0
GPX3 -5081 -3870.0
GPX7 -5153 2186.0
GPX8 -458 1641.0
GRB10 -1615 561.0
GSK3B 897 3200.0
GSR -2148 1119.0
H2AFX 2356 5062.0
HDAC6 -4164 3925.0
HIF1A -1016 5007.0
HIF1AN -2114 -4148.0
HIF3A -3208 -1364.0
HIGD1A -2341 -1757.0
HIRA 832 686.0
HMGA1 598 5099.0
HSBP1 1620 74.0
HSF1 -5373 110.0
HSP90AA1 3656 5261.0
HSP90AB1 -639 4629.0
HSPA12A -3798 -3231.0
HSPA13 4292 4891.0
HSPA14 2830 1760.0
HSPA1A 4887 5277.5
HSPA1B 4676 5277.5
HSPA1L 519 5031.0
HSPA2 4948 3536.0
HSPA4 3842 3873.0
HSPA4L 4705 -62.0
HSPA5 2574 5200.0
HSPA8 3674 5088.0
HSPA9 2342 -1431.0
HSPB8 -5316 5197.0
HSPH1 4143 5073.0
ID1 -1307 3474.0
IGFBP7 505 1360.0
IMPACT -269 1150.0
ITFG2 454 1486.0
JUN 2469 5225.0
KAT5 447 3955.0
KDM6B -5026 -632.0
KPTN -4554 -3976.0
LAMTOR1 -800 -2671.0
LAMTOR2 -1715 -424.0
LAMTOR3 3134 3162.0
LAMTOR4 -2977 2289.0
LAMTOR5 636 -324.0
LIMD1 -1814 -3829.0
LMNB1 3392 2947.0
MAP2K3 -4716 3039.0
MAP2K4 8 -3251.0
MAP2K6 1456 -4876.0
MAP2K7 794 -3887.0
MAP3K5 1249 3914.0
MAP4K4 -4159 766.0
MAPK1 1988 -648.0
MAPK10 -3504 -1859.0
MAPK11 -3385 -333.0
MAPK14 -1562 -1635.0
MAPK3 -1024 3725.0
MAPK7 -729 3565.0
MAPK8 457 1106.0
MAPK9 -3854 -3511.0
MAPKAPK2 -2489 -645.0
MAPKAPK3 -4795 -3142.0
MDM2 3253 3321.0
MDM4 2051 -4809.0
MINK1 -3301 2408.0
MIOS 1011 634.0
MLST8 -3485 -2266.0
MOV10 -4127 1367.0
MRPL18 2996 -4236.0
MTOR -1191 -1922.0
NBN 1286 -1205.0
NDC1 1273 -2350.0
NFKB1 -4233 3315.0
NOX4 2301 1027.0
NPRL2 -2734 1186.0
NPRL3 -2240 -815.0
NR3C1 985 -4192.0
NR3C2 -1723 -18.0
NUDT2 -136 -2521.0
NUP107 3232 2949.0
NUP133 889 -4048.0
NUP153 4762 1533.0
NUP155 4306 -2233.0
NUP160 3998 1035.0
NUP188 2117 3830.0
NUP205 4438 3588.0
NUP214 3124 665.0
NUP35 4571 649.0
NUP37 -327 192.0
NUP43 4562 2216.0
NUP54 4508 3831.0
NUP85 3181 -393.0
NUP88 1244 2212.0
NUP93 -1503 3903.0
NUP98 4235 5066.0
P4HB -2525 4048.0
PHC1 456 -1955.0
PHC2 -3719 4976.0
PHC3 3141 -3012.0
POT1 3936 -4021.0
PPP1R15A 1886 5267.0
PRDX1 605 1340.0
PRDX2 -5293 -2557.0
PRDX3 -443 -3668.0
PRDX5 -3356 -1867.0
PRDX6 -3481 4973.0
PSMA1 2820 3328.0
PSMA3 3434 -4.0
PSMA4 769 958.0
PSMA6 2199 -1044.0
PSMA7 -2980 976.0
PSMB1 954 2628.0
PSMB10 -1800 2907.0
PSMB2 618 2471.0
PSMB4 -235 2096.0
PSMB5 -4113 -606.0
PSMB6 -793 914.0
PSMB7 -831 -1453.0
PSMB8 -675 2066.0
PSMB9 -1611 -2973.0
PSMC1 449 -336.0
PSMC2 -1311 3241.0
PSMC3 -2439 -369.0
PSMC4 2724 1416.0
PSMC5 1212 -1123.0
PSMC6 -2520 3423.0
PSMD1 2619 -1191.0
PSMD10 -1227 525.0
PSMD11 995 5183.0
PSMD12 3831 536.0
PSMD13 821 1665.0
PSMD14 -635 3816.0
PSMD2 -713 -555.0
PSMD3 -3343 2226.0
PSMD4 -214 2558.0
PSMD5 1807 3558.0
PSMD6 3537 -2207.0
PSMD7 -2329 1233.0
PSMD8 -3171 4626.0
PSMD9 4204 -970.0
PSME1 -2771 3350.0
PSME2 -4085 3584.0
PSME3 3333 3379.0
PSME4 1960 -4574.0
PSMF1 683 -1480.0
PTGES3 1328 3635.0
RAD50 306 -3473.0
RAE1 4471 2389.0
RANBP2 4470 -3848.0
RB1 -2449 1464.0
RBBP4 1072 2469.0
RBBP7 -924 -2291.0
RBX1 -733 -968.0
RELA 1783 4531.0
RHEB 172 2951.0
RING1 -1968 -125.0
RNF2 3038 4651.0
RPA1 -1837 -4231.0
RPA2 2889 -1373.0
RPA3 2702 -1706.0
RPL10 -3902 3841.0
RPL11 -2249 2690.0
RPL14 433 1505.0
RPL18 -1782 3926.0
RPL18A -2969 1546.0
RPL19 -502 2402.0
RPL22 1231 -695.0
RPL22L1 3380 4103.0
RPL23 -115 2472.0
RPL26 1047 3247.0
RPL28 -391 2871.0
RPL3 -786 4892.0
RPL30 286 2070.0
RPL31 -595 4273.0
RPL32 -367 2766.0
RPL34 1447 1856.0
RPL35A 812 1955.0
RPL36A 1261 2266.0
RPL37 -715 2388.0
RPL37A -1043 2280.0
RPL38 231 3306.0
RPL3L -5212 -3395.0
RPL4 -522 1026.0
RPL5 1206 4486.0
RPL7 1440 1916.0
RPL8 -2775 2474.0
RPLP2 -2469 2383.0
RPS11 -1582 3395.0
RPS12 -318 3958.0
RPS13 1131 3118.0
RPS14 -1412 1322.0
RPS15 -1799 1989.0
RPS15A -704 2410.0
RPS16 -1828 3864.0
RPS18 -974 2916.0
RPS19 -2045 2954.0
RPS19BP1 -1354 4256.0
RPS20 -1844 4785.0
RPS21 -1536 707.0
RPS23 -68 1922.0
RPS24 256 1742.0
RPS26 -282 2982.0
RPS27A 783 1840.0
RPS27L -616 298.0
RPS29 -1140 2499.0
RPS3 -544 3102.0
RPS4X 83 1892.0
RPS5 -1577 2419.0
RPS6 -245 3549.0
RPS6KA1 -1481 -46.0
RPS6KA2 -4748 -5153.0
RPS6KA3 952 410.0
RPS8 -1593 2271.0
RPS9 -1107 1580.0
RPTOR -4596 2076.0
RRAGA 2383 4477.0
RRAGB -366 -548.0
RRAGC 2091 945.0
RRAGD -4673 -5179.0
SCMH1 -5007 -1597.0
SEC13 730 1702.0
SEH1L 1085 4263.0
SERPINH1 -3526 3768.0
SESN1 -4227 3713.0
SESN2 -2604 5137.0
SH3BP4 -5382 5019.0
SIRT1 4935 4484.0
SLC38A9 969 -2953.0
SOD1 157 807.0
SOD2 -1568 -3943.0
SOD3 -1046 4449.0
SP1 1787 -1016.0
ST13 -123 3413.0
STAT3 -3885 5061.0
STIP1 2780 4885.0
SUZ12 3871 1927.0
SZT2 3003 -2529.0
TCIRG1 -3600 4552.0
TERF1 422 16.0
TERF2 -1834 1195.0
TERF2IP 4692 -1399.0
TFDP1 -2245 -2659.0
TFDP2 4029 -5361.0
TINF2 -1257 1757.0
TNFRSF21 -2507 -4518.0
TNIK 334 -2042.0
TNRC6A 3585 -573.0
TNRC6B 3118 -4527.0
TNRC6C -2020 -1918.0
TP53 575 3751.0
TPR 2984 -1026.0
TRIB3 -1004 3791.0
TXN 1855 4791.0
TXN2 -2838 641.0
TXNRD1 -2444 2445.0
TXNRD2 -4424 -3456.0
UBC 2672 4480.0
UBE2C 4949 463.0
UBE2D1 -1588 -4032.0
UBE2D2 -1986 3383.0
UBE2D3 1424 4934.0
UBE2E1 -1132 -479.0
UBE2S 4441 4268.0
UBN1 2086 3668.0
VEGFA -4571 -5196.0
WDR24 564 -3209.0
WDR59 -3369 -1580.0
WTIP -4938 -615.0
YWHAE 1394 -914.0



Response of EIF2AK4 (GCN2) to amino acid deficiency

Response of EIF2AK4 (GCN2) to amino acid deficiency
metric value
setSize 63
pMANOVA 6.94e-10
p.adjustMANOVA 1.94e-08
s.dist 0.462
s.human -0.0312
s.mouse 0.461
p.human 0.669
p.mouse 2.66e-10




Top 20 genes
Gene human mouse
RPL10 -3902 3841
RPS20 -1844 4785
CEBPB -4699 1850
RPS16 -1828 3864
RPL18 -1782 3926
RPL8 -2775 2474
RPL11 -2249 2690
RPS19 -2045 2954
ATF4 -1161 5122
RPLP2 -2469 2383
RPS11 -1582 3395
RPL18A -2969 1546
RPL3 -786 4892
RPS5 -1577 2419
TRIB3 -1004 3791
RPS8 -1593 2271
RPS15 -1799 1989
RPS29 -1140 2499
RPS18 -974 2916
RPL31 -595 4273

Click HERE to show all gene set members

All member genes
human mouse
ASNS 2808 3601
ATF2 3130 1863
ATF3 522 5240
ATF4 -1161 5122
CEBPB -4699 1850
CEBPG -870 5
DDIT3 -1718 243
EIF2AK4 -3765 -1462
EIF2S1 4274 3125
EIF2S2 3602 -364
FAU 2272 4115
IMPACT -269 1150
RPL10 -3902 3841
RPL11 -2249 2690
RPL14 433 1505
RPL18 -1782 3926
RPL18A -2969 1546
RPL19 -502 2402
RPL22 1231 -695
RPL22L1 3380 4103
RPL23 -115 2472
RPL26 1047 3247
RPL28 -391 2871
RPL3 -786 4892
RPL30 286 2070
RPL31 -595 4273
RPL32 -367 2766
RPL34 1447 1856
RPL35A 812 1955
RPL36A 1261 2266
RPL37 -715 2388
RPL37A -1043 2280
RPL38 231 3306
RPL3L -5212 -3395
RPL4 -522 1026
RPL5 1206 4486
RPL7 1440 1916
RPL8 -2775 2474
RPLP2 -2469 2383
RPS11 -1582 3395
RPS12 -318 3958
RPS13 1131 3118
RPS14 -1412 1322
RPS15 -1799 1989
RPS15A -704 2410
RPS16 -1828 3864
RPS18 -974 2916
RPS19 -2045 2954
RPS20 -1844 4785
RPS21 -1536 707
RPS23 -68 1922
RPS24 256 1742
RPS26 -282 2982
RPS27A 783 1840
RPS27L -616 298
RPS29 -1140 2499
RPS3 -544 3102
RPS4X 83 1892
RPS5 -1577 2419
RPS6 -245 3549
RPS8 -1593 2271
RPS9 -1107 1580
TRIB3 -1004 3791



Cell Cycle Checkpoints

Cell Cycle Checkpoints
metric value
setSize 191
pMANOVA 8.03e-10
p.adjustMANOVA 2.2e-08
s.dist 0.294
s.human 0.219
s.mouse 0.197
p.human 2.07e-07
p.mouse 2.98e-06




Top 20 genes
Gene human mouse
NUP98 4235 5066
CCNE1 4388 4753
PPP2R5A 4590 4219
UBE2S 4441 4268
DBF4 4260 4331
MCM6 3462 4822
KIF18A 3832 4144
MAPRE1 3454 4528
RCC2 4178 3436
ZWINT 2778 5161
PPP2R1B 3028 4619
PPP2CA 4482 3008
CCNA2 3061 4292
YWHAB 3680 3415
INCENP 3676 3359
UBC 2672 4480
H2AFX 2356 5062
RAD1 3205 3561
PSME3 3333 3379
MDM2 3253 3321

Click HERE to show all gene set members

All member genes
human mouse
AHCTF1 4662 -1792
ANAPC1 572 -4087
ANAPC10 1974 2134
ANAPC11 -3265 -1751
ANAPC15 -3393 1787
ANAPC16 -3612 -1148
ANAPC2 -2185 -3532
ANAPC4 -720 -4834
ANAPC5 1284 -2104
ANAPC7 1595 2349
ATM 1449 -5067
ATR 1983 -63
B9D2 1676 -553
BABAM1 -1363 -802
BLM 1103 4695
BRCC3 -375 -3072
BRE 696 -809
BUB3 4201 1662
CCNA2 3061 4292
CCNE1 4388 4753
CCNE2 4667 147
CDC16 86 -1984
CDC23 3850 -1171
CDC25A 4090 2308
CDC26 2750 2457
CDC27 665 1230
CDC7 2421 2065
CDK1 1580 3263
CDK2 849 2686
CDKN1A -4927 5092
CDKN1B -3284 -2450
CENPC 3555 -2660
CENPL 3768 2470
CENPO 1005 440
CENPQ 1344 5001
CENPT -2196 3930
CHEK2 1311 1076
CKAP5 -3973 -1370
CLASP1 -3713 1181
CLASP2 2507 -309
CLIP1 418 -4689
DBF4 4260 4331
DNA2 37 2385
DSN1 2075 534
DYNC1H1 -1442 -2348
DYNC1I2 2591 -2971
DYNC1LI1 2883 1316
DYNC1LI2 1750 -1620
DYNLL1 -1331 4245
FAM175A -3897 129
H2AFX 2356 5062
HUS1 2435 -4471
INCENP 3676 3359
ITGB3BP 1048 -2448
KAT5 447 3955
KIF18A 3832 4144
KIF2A -4390 4818
MAD1L1 -3382 2990
MAD2L1 1101 3554
MAPRE1 3454 4528
MCM2 -3977 2851
MCM3 600 4761
MCM4 -610 4841
MCM5 -1490 4861
MCM6 3462 4822
MCM7 2515 2881
MCM8 -3355 -3274
MDC1 841 2997
MDM2 3253 3321
MDM4 2051 -4809
MIS12 2400 4069
NBN 1286 -1205
NDE1 4322 -2784
NDEL1 4631 1071
NUDC 3212 2586
NUP107 3232 2949
NUP133 889 -4048
NUP160 3998 1035
NUP37 -327 192
NUP43 4562 2216
NUP85 3181 -393
NUP98 4235 5066
ORC2 1022 4505
ORC3 -1627 -3964
ORC4 3929 1594
ORC5 4429 -566
ORC6 2184 -425
PAFAH1B1 -2026 -2663
PCBP4 -5523 -1872
PHF20 819 -2632
PIAS4 342 2088
PPP1CC 4081 399
PPP2CA 4482 3008
PPP2CB 2458 4129
PPP2R1A -4013 -696
PPP2R1B 3028 4619
PPP2R5A 4590 4219
PPP2R5B -1524 121
PPP2R5C -2508 -3684
PPP2R5D -3449 -2058
PPP2R5E 4644 1539
PSMA1 2820 3328
PSMA3 3434 -4
PSMA4 769 958
PSMA6 2199 -1044
PSMA7 -2980 976
PSMB1 954 2628
PSMB10 -1800 2907
PSMB2 618 2471
PSMB4 -235 2096
PSMB5 -4113 -606
PSMB6 -793 914
PSMB7 -831 -1453
PSMB8 -675 2066
PSMB9 -1611 -2973
PSMC1 449 -336
PSMC2 -1311 3241
PSMC3 -2439 -369
PSMC4 2724 1416
PSMC5 1212 -1123
PSMC6 -2520 3423
PSMD1 2619 -1191
PSMD10 -1227 525
PSMD11 995 5183
PSMD12 3831 536
PSMD13 821 1665
PSMD14 -635 3816
PSMD2 -713 -555
PSMD3 -3343 2226
PSMD4 -214 2558
PSMD5 1807 3558
PSMD6 3537 -2207
PSMD7 -2329 1233
PSMD8 -3171 4626
PSMD9 4204 -970
PSME1 -2771 3350
PSME2 -4085 3584
PSME3 3333 3379
PSME4 1960 -4574
PSMF1 683 -1480
RAD1 3205 3561
RAD17 2273 808
RAD50 306 -3473
RAD9A -3149 -154
RANBP2 4470 -3848
RANGAP1 483 4340
RBBP8 3047 3316
RCC2 4178 3436
RFC2 622 -1170
RFC3 2151 4113
RFC4 3542 964
RFC5 1409 3528
RFWD2 2172 -2186
RHNO1 -4573 -113
RMI1 4517 -56
RMI2 -2759 -5106
RNF168 4346 884
RNF8 975 -354
RPA1 -1837 -4231
RPA2 2889 -1373
RPA3 2702 -1706
RPS27A 783 1840
SEC13 730 1702
SEH1L 1085 4263
SKA2 2399 907
SUMO1 4213 1399
TAOK1 1644 -3805
TOP3A 2607 1632
TOPBP1 2183 4567
TP53 575 3751
TP53BP1 -643 3904
UBC 2672 4480
UBE2C 4949 463
UBE2D1 -1588 -4032
UBE2E1 -1132 -479
UBE2N 2545 3996
UBE2S 4441 4268
UBE2V2 -334 1298
UIMC1 835 -375
WEE1 -4561 1755
WRN 98 2665
XPO1 990 1809
YWHAB 3680 3415
YWHAE 1394 -914
YWHAG -2372 -3104
YWHAH -2777 4700
YWHAQ 963 3739
YWHAZ 2019 4495
ZNF385A -5211 4005
ZW10 1474 1263
ZWINT 2778 5161



Respiratory electron transport

Respiratory electron transport
metric value
setSize 92
pMANOVA 1.45e-09
p.adjustMANOVA 3.89e-08
s.dist 0.408
s.human -0.178
s.mouse -0.367
p.human 0.0033
p.mouse 1.26e-09




Top 20 genes
Gene human mouse
SDHA -4773 -4591
ACAD9 -4578 -4558
CYC1 -4147 -4031
MT-CO1 -3167 -4114
UQCRC1 -3333 -3667
COX14 -2772 -4368
NDUFV1 -4226 -2736
SDHC -3712 -3001
TRAP1 -5265 -2063
NDUFAF6 -2555 -4096
ETFB -3614 -2740
NDUFS3 -3567 -2753
COQ10A -3553 -2653
NDUFS7 -4871 -1906
NDUFB8 -3020 -2917
NDUFS8 -4325 -1999
NDUFS2 -3026 -2814
NDUFB7 -4222 -1994
ECSIT -2655 -2846
MT-ND5 -3244 -2323

Click HERE to show all gene set members

All member genes
human mouse
ACAD9 -4578 -4558
COQ10A -3553 -2653
COQ10B 4344 4255
COX11 -2860 -1166
COX14 -2772 -4368
COX16 -2259 -1943
COX18 -554 635
COX19 3053 3493
COX20 1104 -2275
COX4I1 -2357 -1289
COX5A -2511 -2550
COX5B -2559 458
COX6A1 2259 2241
COX6B1 -2231 -855
COX6C -18 -845
COX7B 144 -729
COX7C -1495 -176
COX8A -4337 2642
CYC1 -4147 -4031
ECSIT -2655 -2846
ETFA 3160 -2761
ETFB -3614 -2740
ETFDH 1884 -4586
LRPPRC 1656 -4390
MT-CO1 -3167 -4114
MT-CYB -1355 -2353
MT-ND1 -353 -2211
MT-ND2 -1120 -2087
MT-ND4 -2086 -1594
MT-ND5 -3244 -2323
MT-ND6 816 -4592
NDUFA1 -737 311
NDUFA10 -1955 -3119
NDUFA11 -1033 -1135
NDUFA12 -1315 -659
NDUFA13 -2253 -2553
NDUFA2 -1290 -1978
NDUFA3 -3805 -593
NDUFA4 -393 -682
NDUFA5 534 -1670
NDUFA6 -77 -3389
NDUFA7 -465 -1825
NDUFA8 -602 -2505
NDUFA9 -2868 -2075
NDUFAB1 1151 -3257
NDUFAF1 1175 -4265
NDUFAF2 3504 -3248
NDUFAF3 -3581 -1264
NDUFAF4 3740 -2020
NDUFAF5 29 -977
NDUFAF6 -2555 -4096
NDUFAF7 2971 -457
NDUFB10 -3373 -2096
NDUFB11 -2103 -2860
NDUFB2 -3732 -962
NDUFB3 852 -1934
NDUFB4 -311 -1522
NDUFB5 -2039 -1176
NDUFB6 928 -307
NDUFB7 -4222 -1994
NDUFB8 -3020 -2917
NDUFB9 -996 -3435
NDUFC1 -664 -2904
NDUFC2 34 -2430
NDUFS1 -1544 -4374
NDUFS2 -3026 -2814
NDUFS3 -3567 -2753
NDUFS4 -1690 -2444
NDUFS5 -1235 -1924
NDUFS6 -1332 -980
NDUFS7 -4871 -1906
NDUFS8 -4325 -1999
NDUFV1 -4226 -2736
NDUFV3 -2378 -2590
NUBPL -1541 -3546
SCO1 3577 1708
SCO2 -1941 -772
SDHA -4773 -4591
SDHB 431 -3707
SDHC -3712 -3001
SURF1 -1748 -4099
TACO1 651 -4262
TIMMDC1 213 -1107
TMEM126B 1024 1869
TRAP1 -5265 -2063
UQCR10 -3139 -259
UQCRB 403 -3715
UQCRC1 -3333 -3667
UQCRC2 551 -3907
UQCRFS1 -151 -3062
UQCRH -1532 -1753
UQCRQ -1767 -1856



Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.

Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
metric value
setSize 96
pMANOVA 1.52e-09
p.adjustMANOVA 3.99e-08
s.dist 0.399
s.human -0.176
s.mouse -0.358
p.human 0.00289
p.mouse 1.44e-09




Top 20 genes
Gene human mouse
SDHA -4773 -4591
ACAD9 -4578 -4558
CYC1 -4147 -4031
MT-CO1 -3167 -4114
UQCRC1 -3333 -3667
COX14 -2772 -4368
SLC25A27 -2478 -4864
NDUFV1 -4226 -2736
SDHC -3712 -3001
TRAP1 -5265 -2063
NDUFAF6 -2555 -4096
ETFB -3614 -2740
NDUFS3 -3567 -2753
COQ10A -3553 -2653
NDUFS7 -4871 -1906
NDUFB8 -3020 -2917
NDUFS8 -4325 -1999
NDUFS2 -3026 -2814
NDUFB7 -4222 -1994
ECSIT -2655 -2846

Click HERE to show all gene set members

All member genes
human mouse
ACAD9 -4578 -4558
COQ10A -3553 -2653
COQ10B 4344 4255
COX11 -2860 -1166
COX14 -2772 -4368
COX16 -2259 -1943
COX18 -554 635
COX19 3053 3493
COX20 1104 -2275
COX4I1 -2357 -1289
COX5A -2511 -2550
COX5B -2559 458
COX6A1 2259 2241
COX6B1 -2231 -855
COX6C -18 -845
COX7B 144 -729
COX7C -1495 -176
COX8A -4337 2642
CYC1 -4147 -4031
ECSIT -2655 -2846
ETFA 3160 -2761
ETFB -3614 -2740
ETFDH 1884 -4586
LRPPRC 1656 -4390
MT-CO1 -3167 -4114
MT-CYB -1355 -2353
MT-ND1 -353 -2211
MT-ND2 -1120 -2087
MT-ND4 -2086 -1594
MT-ND5 -3244 -2323
MT-ND6 816 -4592
NDUFA1 -737 311
NDUFA10 -1955 -3119
NDUFA11 -1033 -1135
NDUFA12 -1315 -659
NDUFA13 -2253 -2553
NDUFA2 -1290 -1978
NDUFA3 -3805 -593
NDUFA4 -393 -682
NDUFA5 534 -1670
NDUFA6 -77 -3389
NDUFA7 -465 -1825
NDUFA8 -602 -2505
NDUFA9 -2868 -2075
NDUFAB1 1151 -3257
NDUFAF1 1175 -4265
NDUFAF2 3504 -3248
NDUFAF3 -3581 -1264
NDUFAF4 3740 -2020
NDUFAF5 29 -977
NDUFAF6 -2555 -4096
NDUFAF7 2971 -457
NDUFB10 -3373 -2096
NDUFB11 -2103 -2860
NDUFB2 -3732 -962
NDUFB3 852 -1934
NDUFB4 -311 -1522
NDUFB5 -2039 -1176
NDUFB6 928 -307
NDUFB7 -4222 -1994
NDUFB8 -3020 -2917
NDUFB9 -996 -3435
NDUFC1 -664 -2904
NDUFC2 34 -2430
NDUFS1 -1544 -4374
NDUFS2 -3026 -2814
NDUFS3 -3567 -2753
NDUFS4 -1690 -2444
NDUFS5 -1235 -1924
NDUFS6 -1332 -980
NDUFS7 -4871 -1906
NDUFS8 -4325 -1999
NDUFV1 -4226 -2736
NDUFV3 -2378 -2590
NUBPL -1541 -3546
SCO1 3577 1708
SCO2 -1941 -772
SDHA -4773 -4591
SDHB 431 -3707
SDHC -3712 -3001
SLC25A14 3834 1871
SLC25A27 -2478 -4864
SURF1 -1748 -4099
TACO1 651 -4262
TIMMDC1 213 -1107
TMEM126B 1024 1869
TRAP1 -5265 -2063
UCP2 -4949 5039
UCP3 -684 -5360
UQCR10 -3139 -259
UQCRB 403 -3715
UQCRC1 -3333 -3667
UQCRC2 551 -3907
UQCRFS1 -151 -3062
UQCRH -1532 -1753
UQCRQ -1767 -1856



Hemostasis

Hemostasis
metric value
setSize 349
pMANOVA 3.13e-09
p.adjustMANOVA 8.04e-08
s.dist 0.18
s.human -0.141
s.mouse 0.111
p.human 7.12e-06
p.mouse 0.000396




Top 20 genes
Gene human mouse
SERPINB6 -5411 4903.0
ITGA5 -4752 5178.0
BCAR1 -4922 4966.0
SIRPA -5627 4222.0
EHD1 -4458 5164.0
VCL -4538 5034.0
KIF2A -4390 4818.0
ANXA2 -4123 5025.0
SELPLG -4620 4444.0
P2RX5 -4736 4185.5
SH2B2 -4553 4224.0
PPIA -4031 4697.0
MAFF -3749 4884.0
GRB2 -4050 4496.0
KIF21B -4761 3667.0
CSK -3610 4738.0
ITGA3 -5514 3010.0
TGFB1 -3111 4943.0
CD63 -3297 4594.0
PDPN -3304 4584.0

Click HERE to show all gene set members

All member genes
human mouse
AAMP 2657 111.0
ABCC4 1368 -4019.0
ABHD12 -778 606.0
ABHD6 -2808 -643.0
ABL1 -4533 -3545.0
ACTN1 -676 3696.0
ACTN2 -3104 3454.0
ACTN4 1805 4001.0
ADRA2A -4661 -1779.0
AK3 -3164 -5344.0
AKAP1 -5093 -4282.0
AKAP10 3696 -3810.0
AKT1 -4954 342.0
ALDOA -5575 -3482.0
ANGPT1 -853 -4174.0
ANXA2 -4123 5025.0
ANXA5 2401 4339.0
APLP2 1316 -575.0
APOOL -69 -612.0
APP -2792 582.0
ARRB1 -3133 -14.0
ARRB2 -1089 4317.0
ATP1B1 2576 -3091.0
ATP1B3 -598 3075.0
ATP2A1 -5479 -4584.0
ATP2A2 -2976 515.0
ATP2A3 -4467 1862.0
ATP2B1 2034 159.0
ATP2B3 -4422 -5220.0
ATP2B4 -2762 -68.0
BCAR1 -4922 4966.0
BRPF3 3668 4189.0
BSG -2248 -2113.0
C1QBP 3798 -456.0
CABLES1 -4484 459.0
CABLES2 -4326 337.0
CALM1 -4464 96.0
CALU 3246 4872.0
CAP1 2590 4328.0
CAPZA2 -1777 -3734.0
CAPZB -3165 -2667.0
CAV1 -646 -652.0
CBX5 1538 -4637.0
CD109 -3329 4406.0
CD36 -582 -3838.0
CD44 837 4987.0
CD47 -2184 2680.0
CD63 -3297 4594.0
CD9 2203 2358.0
CD99L2 -4169 3366.0
CDC37L1 -111 -3253.0
CDC42 3308 754.0
CDK2 849 2686.0
CDK5 -1007 -793.0
CFL1 -909 4720.0
CHID1 -2865 1445.0
CLEC3B -629 -822.0
CLU 1629 4164.0
CRK 2145 2262.0
CSK -3610 4738.0
CYB5R1 -4864 -3744.0
DAGLA -5158 -4484.0
DAGLB 3782 -2382.0
DGKA -2368 -2792.0
DGKB -4489 -1726.0
DGKD -5077 333.0
DGKE 1911 -4364.0
DGKH 3337 4302.0
DGKQ -2188 -2361.0
DGKZ -5581 -4639.0
DOCK1 -226 -41.0
DOCK10 4096 1667.0
DOCK11 -4738 2787.0
DOCK4 1844 -4767.0
DOCK5 -1286 1895.0
DOCK6 -1306 -2241.0
DOCK7 4461 1673.0
DOCK8 -3782 2912.0
DOCK9 -2258 -4938.0
ECM1 -3535 3170.0
EGF -4568 -5354.0
EHD1 -4458 5164.0
EHD2 -5214 -723.0
EHD3 -3462 3965.0
ENDOD1 -4813 1977.0
F11R -2302 -673.0
F13A1 -2059 3642.0
F2R 1667 3544.0
F3 -1733 2260.0
F8 -941 -4201.0
FAM3C -1909 567.0
FERMT3 -2875 4879.0
FLNA -3248 3245.0
FN1 35 4022.0
FYN -2850 3685.0
GAS6 -5013 -3151.0
GLG1 -2906 544.0
GNA11 -1689 677.0
GNA12 -3059 4669.0
GNA13 -209 4537.0
GNAI1 183 -419.0
GNAI2 800 3632.0
GNAI3 4221 3815.0
GNAQ 4906 2996.0
GNAS -3163 -641.0
GNB1 177 4937.0
GNB2 -3870 3905.0
GNB3 -3272 -1723.0
GNB4 -3491 -3375.0
GNB5 879 160.0
GNG11 4695 -2336.0
GNG12 612 -821.0
GNG2 802 -279.0
GNG5 415 -1583.0
GNG7 -2742 -5085.0
GPC1 -5269 -2966.0
GRB14 -1485 -3347.0
GRB2 -4050 4496.0
GTPBP2 -1376 -4746.0
GUCY1B3 4506 -4233.0
GYPC -3255 -4113.0
HABP4 -4207 -2579.0
HDAC2 4386 -1101.0
HMG20B 704 291.0
HRAS -4545 -3997.0
HSPA5 2574 5200.0
IGF2 -4754 -3030.0
INPP5D -2433 4327.0
IRF1 -1565 984.0
IRF2 -3387 2261.0
ISLR -2846 191.0
ITGA1 1757 -4136.0
ITGA10 -1878 -986.0
ITGA3 -5514 3010.0
ITGA4 -2878 -5141.0
ITGA5 -4752 5178.0
ITGA6 -1002 -5301.0
ITGAM -2633 5045.0
ITGAV -819 50.0
ITGAX -896 3851.0
ITGB1 956 4614.0
ITGB2 -107 4993.0
ITGB3 -488 4915.0
ITPK1 -2911 3386.0
ITPR1 4903 -2230.0
ITPR2 1242 -3115.0
ITPR3 -3631 -3441.0
JAK2 -2569 -5057.0
JAM2 -5328 -5016.0
JAM3 1283 -3969.0
JMJD1C 312 4196.0
KCNMA1 -2841 348.0
KDM1A 249 4852.0
KIF11 2319 4310.0
KIF13B -1749 -1605.0
KIF16B 3552 -5369.0
KIF18A 3832 4144.0
KIF1A 905 2318.0
KIF1B 1513 -3963.0
KIF1C -5118 -3685.0
KIF21A 4624 -2091.0
KIF21B -4761 3667.0
KIF23 1216 4134.0
KIF26B -3147 -4616.0
KIF2A -4390 4818.0
KIF3A 4718 1513.0
KIF3B 3571 1699.0
KIF3C -3766 -4729.0
KIF5A 4430 731.0
KIF5B 838 1727.0
KIF5C 4658 -750.0
KIFAP3 -1339 -4750.0
KIFC2 -4370 -3737.0
KLC1 -3922 2366.0
KLC2 -1732 -2589.0
KLC4 -3559 -1292.0
KRAS 3546 4454.0
L1CAM 945 2245.0
LAMP2 -2579 848.0
LGALS3BP -4500 256.0
LHFPL2 161 1132.0
LYN 785 3984.0
MAFF -3749 4884.0
MAFG -4198 -1240.0
MAFK -374 5009.0
MAGED2 -4316 -1732.0
MANF 2108 5130.0
MAPK1 1988 -648.0
MAPK14 -1562 -1635.0
MAPK3 -1024 3725.0
MERTK -1975 -90.0
MFN1 4339 -4605.0
MFN2 -1456 -4825.0
MGLL -5374 -4338.0
MICAL1 -4962 2566.0
MIF -2307 2943.0
NHLRC2 2062 -835.0
NOS1 -4260 -4935.0
NRAS 4354 69.0
OLA1 1860 -3842.0
ORAI2 936 811.0
P2RX4 -1108 2865.0
P2RX5 -4736 4185.5
P2RX6 -5567 -4773.0
PAFAH2 -3734 -2141.0
PCDH7 3641 4204.0
PCYOX1L 201 587.0
PDE10A 2072 2825.0
PDE1A 2411 710.0
PDE5A -78 -1006.0
PDGFA -4328 -4456.0
PDGFB -606 3347.0
PDPK1 3443 2222.0
PDPN -3304 4584.0
PFN1 467 1712.0
PHACTR2 3632 -4770.0
PHF21A -4739 -629.0
PICK1 -881 -3878.0
PIK3CA 365 2811.0
PIK3CB 2760 4994.0
PIK3R1 2896 -3147.0
PIK3R3 3188 577.0
PLA2G4A 603 3705.0
PLAT 1414 3348.0
PLAU -548 1192.0
PLAUR -638 3744.0
PLCG1 -3955 -4939.0
PLEK -3003 3907.0
PPIA -4031 4697.0
PPIL2 -4421 -2670.0
PPP2CA 4482 3008.0
PPP2CB 2458 4129.0
PPP2R1A -4013 -696.0
PPP2R1B 3028 4619.0
PPP2R5A 4590 4219.0
PPP2R5B -1524 121.0
PPP2R5C -2508 -3684.0
PPP2R5D -3449 -2058.0
PPP2R5E 4644 1539.0
PRCP 970 870.0
PRKACA -4691 -1606.0
PRKACB -2659 -1546.0
PRKAR1A -3106 3030.0
PRKAR1B -2442 2761.0
PRKAR2A -2664 -655.0
PRKAR2B 3460 2616.0
PRKCA -2938 -2924.0
PRKCD -4276 3377.0
PRKCE -4307 -3088.0
PRKCQ -5095 -4882.0
PRKG1 1401 5121.0
PROCR 22 -2206.0
PROS1 103 2938.0
PSAP -2247 -4040.0
PTGIR -370 3143.0
PTK2 -2497 -1508.0
PTPN1 1531 4585.0
PTPN11 -1575 -666.0
PTPN6 -931 4799.0
QSOX1 2045 2998.0
RAB27B 2206 -3901.0
RAB5A 2109 4941.0
RAC1 2525 1457.0
RAC2 41 4946.0
RACGAP1 4239 3684.0
RAF1 1712 -1646.0
RAP1A -689 3710.0
RAP1B 4479 4565.0
RAPGEF3 108 -2918.0
RAPGEF4 4622 3189.0
RARRES2 -3551 -534.0
RASGRP2 -2556 -4280.0
RCOR1 4776 -5.0
RHOA 539 4193.0
RHOB 4609 5128.0
RHOG -1207 4926.0
S100A10 -1995 5141.0
SCCPDH -2874 -4841.0
SDC1 -2046 212.0
SDC2 1756 4483.0
SDC3 -4619 2809.0
SDC4 -2393 5153.0
SELPLG -4620 4444.0
SERPINB6 -5411 4903.0
SERPINB8 2357 4482.0
SERPINE1 -211 5168.0
SERPINE2 687 -2458.0
SERPING1 78 286.0
SH2B1 -3841 -971.0
SH2B2 -4553 4224.0
SH2B3 -4833 2922.0
SHC1 3976 3605.0
SIN3A 3397 267.0
SIRPA -5627 4222.0
SLC16A1 -987 5075.0
SLC16A3 -4751 -4158.0
SLC3A2 -656 3875.0
SLC7A5 -2463 4541.0
SLC7A6 -5241 -1106.0
SLC7A7 -3748 134.0
SLC7A8 -1965 -1871.0
SLC8A1 754 -3579.0
SLC8A3 -5477 -3886.0
SOD1 157 807.0
SOS1 -1962 -1007.0
SPARC -2672 -571.0
SRC -3910 1378.0
SRGN 1742 1512.0
SRI -4069 3480.0
STIM1 -3417 -2324.0
STX4 -2347 78.0
STXBP3 3943 -3841.0
SYTL4 1697 -1078.0
TAGLN2 -25 4899.0
TEK 3580 -2188.0
TEX264 -5025 1829.0
TFPI 894 199.0
TGFB1 -3111 4943.0
TGFB2 4602 1861.0
TGFB3 -5326 -2035.0
THBD -1571 3844.0
THBS1 762 4431.0
THPO -2147 -2609.0
TIMP1 -1317 5239.0
TIMP3 1582 -4602.0
TLN1 -3918 2975.0
TMX3 -1118 -3075.0
TNFRSF10A -3936 1259.5
TNFRSF10B -1612 1259.5
TNFRSF10D -3227 1259.5
TOR4A 2444 -784.0
TP53 575 3751.0
TSPAN7 -5133 327.0
TTN 3968 -4448.0
TUBA4A -5342 2072.0
VAV2 -4959 -899.0
VAV3 187 -1063.0
VCL -4538 5034.0
VEGFA -4571 -5196.0
VEGFB -4617 -136.0
VEGFC 1169 1473.0
VPS45 -4193 -657.0
VTI1B 609 -235.0
VWF -779 -106.0
WDR1 -313 5135.0
WEE1 -4561 1755.0
YES1 -176 -2941.0
YWHAZ 2019 4495.0
ZFPM1 71 1174.0



Interleukin-4 and Interleukin-13 signaling

Interleukin-4 and Interleukin-13 signaling
metric value
setSize 64
pMANOVA 4.62e-09
p.adjustMANOVA 1.16e-07
s.dist 0.422
s.human -0.13
s.mouse 0.401
p.human 0.0724
p.mouse 2.96e-08




Top 20 genes
Gene human mouse
CDKN1A -4927 5092
STAT3 -3885 5061
IL6R -5515 3267
BCL2L1 -5181 3434
IL4R -3335 4935
TGFB1 -3111 4943
VIM -3027 4772
HMOX1 -2843 5071
JUNB -2593 5221
ITGAM -2633 5045
IL13RA1 -1847 4516
JAK1 -1869 4228
F13A1 -2059 3642
IL2RG -1943 3730
TIMP1 -1317 5239
HIF1A -1016 5007
TNFRSF1B -874 4595
ITGAX -896 3851
IRF4 -1166 2585
AKT1 -4954 342

Click HERE to show all gene set members

All member genes
human mouse
AKT1 -4954 342
ANXA1 537 4544
BCL2 -4633 -1108
BCL2L1 -5181 3434
BCL6 -5018 -4816
CCL2 2620 5111
CCND1 757 529
CD36 -582 -3838
CDKN1A -4927 5092
COL1A2 -1712 -377
F13A1 -2059 3642
FGF2 751 -1095
FN1 35 4022
FOS 1865 5273
FOXO1 -432 1302
FOXO3 -42 -1131
FSCN1 1705 -932
HIF1A -1016 5007
HMOX1 -2843 5071
HSP90AA1 3656 5261
HSP90B1 460 4944
HSPA8 3674 5088
ICAM1 1056 4172
IL13RA1 -1847 4516
IL2RG -1943 3730
IL4R -3335 4935
IL6R -5515 3267
IRF4 -1166 2585
ITGAM -2633 5045
ITGAX -896 3851
ITGB1 956 4614
ITGB2 -107 4993
JAK1 -1869 4228
JAK2 -2569 -5057
JUNB -2593 5221
LAMA5 -5584 -2744
MAOA -96 3927
MCL1 2837 4826
MMP2 -692 -2003
MYC 3994 4886
NDN 1146 1877
PIK3R1 2896 -3147
PIM1 -228 4294
POU2F1 3019 -3333
RHOU -4229 -325
RORA -5056 -2699
RORC -5248 -4317
S1PR1 2689 1552
SOCS1 199 4033
SOCS3 -283 5103
SOCS5 4145 1886
STAT1 236 -1738
STAT3 -3885 5061
STAT6 -5317 -1263
TGFB1 -3111 4943
TIMP1 -1317 5239
TNFRSF1B -874 4595
TP53 575 3751
TWIST1 2624 2962
TYK2 -3123 -50
VCAM1 2866 4713
VEGFA -4571 -5196
VIM -3027 4772
ZEB1 -4223 -195



Peptide chain elongation

Peptide chain elongation
metric value
setSize 53
pMANOVA 5.61e-09
p.adjustMANOVA 1.38e-07
s.dist 0.472
s.human -0.0686
s.mouse 0.467
p.human 0.388
p.mouse 4.29e-09




Top 20 genes
Gene human mouse
RPL10 -3902 3841
RPS20 -1844 4785
RPS16 -1828 3864
RPL18 -1782 3926
RPL8 -2775 2474
EEF1A1 -2150 2931
RPL11 -2249 2690
RPS19 -2045 2954
RPLP2 -2469 2383
RPS11 -1582 3395
RPL18A -2969 1546
RPL3 -786 4892
RPS5 -1577 2419
RPS8 -1593 2271
RPS15 -1799 1989
RPS29 -1140 2499
RPS18 -974 2916
RPL31 -595 4273
RPL37A -1043 2280
RPS14 -1412 1322

Click HERE to show all gene set members

All member genes
human mouse
EEF1A1 -2150 2931
EEF2 -2853 -853
FAU 2272 4115
RPL10 -3902 3841
RPL11 -2249 2690
RPL14 433 1505
RPL18 -1782 3926
RPL18A -2969 1546
RPL19 -502 2402
RPL22 1231 -695
RPL22L1 3380 4103
RPL23 -115 2472
RPL26 1047 3247
RPL28 -391 2871
RPL3 -786 4892
RPL30 286 2070
RPL31 -595 4273
RPL32 -367 2766
RPL34 1447 1856
RPL35A 812 1955
RPL36A 1261 2266
RPL37 -715 2388
RPL37A -1043 2280
RPL38 231 3306
RPL3L -5212 -3395
RPL4 -522 1026
RPL5 1206 4486
RPL7 1440 1916
RPL8 -2775 2474
RPLP2 -2469 2383
RPS11 -1582 3395
RPS12 -318 3958
RPS13 1131 3118
RPS14 -1412 1322
RPS15 -1799 1989
RPS15A -704 2410
RPS16 -1828 3864
RPS18 -974 2916
RPS19 -2045 2954
RPS20 -1844 4785
RPS21 -1536 707
RPS23 -68 1922
RPS24 256 1742
RPS26 -282 2982
RPS27A 783 1840
RPS27L -616 298
RPS29 -1140 2499
RPS3 -544 3102
RPS4X 83 1892
RPS5 -1577 2419
RPS6 -245 3549
RPS8 -1593 2271
RPS9 -1107 1580



Here is the session info with all the versions of packages used.

sessionInfo()
## R version 4.0.2 (2020-06-22)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 18.04.5 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.7.1
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.7.1
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.1.0               GGally_2.0.0               
##  [3] ggplot2_3.3.2               reshape2_1.4.4             
##  [5] beeswarm_0.2.3              gplots_3.1.0               
##  [7] gtools_3.8.2                tibble_3.0.4               
##  [9] dplyr_1.0.2                 echarts4r_0.3.3            
## [11] DESeq2_1.28.1               SummarizedExperiment_1.18.2
## [13] DelayedArray_0.14.1         matrixStats_0.57.0         
## [15] Biobase_2.48.0              GenomicRanges_1.40.0       
## [17] GenomeInfoDb_1.24.2         IRanges_2.22.2             
## [19] S4Vectors_0.26.1            BiocGenerics_0.34.0        
## [21] mitch_1.0.10               
## 
## loaded via a namespace (and not attached):
##  [1] bitops_1.0-6           bit64_4.0.5            RColorBrewer_1.1-2    
##  [4] rprojroot_1.3-2        tools_4.0.2            backports_1.1.10      
##  [7] R6_2.4.1               KernSmooth_2.23-17     DBI_1.1.0             
## [10] colorspace_1.4-1       withr_2.3.0            tidyselect_1.1.0      
## [13] gridExtra_2.3          bit_4.0.4              compiler_4.0.2        
## [16] desc_1.2.0             labeling_0.4.2         caTools_1.18.0        
## [19] scales_1.1.1           genefilter_1.70.0      stringr_1.4.0         
## [22] digest_0.6.26          rmarkdown_2.5          XVector_0.28.0        
## [25] pkgconfig_2.0.3        htmltools_0.5.0        highr_0.8             
## [28] fastmap_1.0.1          htmlwidgets_1.5.2      rlang_0.4.8           
## [31] RSQLite_2.2.1          shiny_1.5.0            generics_0.0.2        
## [34] farver_2.0.3           jsonlite_1.7.1         BiocParallel_1.22.0   
## [37] RCurl_1.98-1.2         magrittr_1.5           GenomeInfoDbData_1.2.3
## [40] Matrix_1.2-18          Rcpp_1.0.5             munsell_0.5.0         
## [43] lifecycle_0.2.0        stringi_1.5.3          yaml_2.2.1            
## [46] MASS_7.3-53            zlibbioc_1.34.0        plyr_1.8.6            
## [49] grid_4.0.2             blob_1.2.1             promises_1.1.1        
## [52] crayon_1.3.4           lattice_0.20-41        splines_4.0.2         
## [55] annotate_1.66.0        locfit_1.5-9.4         knitr_1.30            
## [58] pillar_1.4.6           geneplotter_1.66.0     XML_3.99-0.5          
## [61] glue_1.4.2             evaluate_0.14          vctrs_0.3.4           
## [64] httpuv_1.5.4           testthat_2.3.2         gtable_0.3.0          
## [67] purrr_0.3.4            reshape_0.8.8          assertthat_0.2.1      
## [70] xfun_0.18              mime_0.9               xtable_1.8-4          
## [73] later_1.1.0.1          survival_3.2-7         AnnotationDbi_1.50.3  
## [76] memoise_1.1.0          ellipsis_0.3.1

END of report