date generated: 2020-08-06

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

##                        x
## 0610005C13Rik  0.5455811
## 0610009B22Rik -0.2758387
## 0610009E02Rik -0.1942335
## 0610009L18Rik  0.6285430
## 0610010F05Rik -1.9585193
## 0610012D04Rik -7.3024303

Here are some metrics about the input data profile:

Profile metrics
Profile metrics
num_genesets 26
num_genes_in_profile 16428
duplicated_genes_present 0
num_profile_genes_in_sets 1115
num_profile_genes_not_in_sets 15313

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used: GMT file of genesets: enhancer_motifs.gmt

Gene sets metrics
Gene sets metrics
num_genesets 26
num_genesets_excluded 9
num_genesets_included 17

Differential pathway expression


Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 17 gene sets

set setSize pANOVA s.dist p.adjustANOVA
motif21.motif.bed PR(NR) 21 0.008080 -0.33400 0.06860
motif12.motif.bed TEAD2(TEA) 68 0.000323 -0.25200 0.00548
motif4.motif.bed GRE(NR),IR3 32 0.061100 -0.19100 0.25000
motif8.motif.bed TEAD4(TEA) 32 0.061100 -0.19100 0.25000
motif17.motif.bed TEAD(TEA) 21 0.172000 0.17200 0.37200
motif5.motif.bed Six1(Homeobox) 21 0.203000 0.16000 0.38400
motif3.motif.bed GRE(NR),IR3 34 0.175000 -0.13400 0.37200
motif1.motif.bed Six2(Homeobox) 92 0.073600 0.10800 0.25000
motif14.motif.bed Six4(Homeobox) 114 0.108000 -0.08710 0.30700
motif11.motif.bed Atf1(bZIP) 22 0.487000 0.08560 0.55200
motif10.motif.bed Mef2a(MADS) 51 0.361000 0.07390 0.51200
motif19.motif.bed TGA1(bZIP) 66 0.438000 -0.05530 0.53700
motif23.motif.bed bZIP50(bZIP) 70 0.443000 -0.05310 0.53700
motif2.motif.bed PGR(NR) 186 0.332000 0.04130 0.51200
motif20.motif.bed Atf2(bZIP) 337 0.308000 -0.03240 0.51200
motif6.motif.bed ARE(NR) 73 0.778000 0.01910 0.82700
motif7.motif.bed NF1-halfsite(CTF) 537 0.926000 -0.00236 0.92600


Results (complete table)


Click HERE to show results for all gene sets

Complete results
set setSize pANOVA s.dist p.adjustANOVA
motif21.motif.bed PR(NR) 21 0.008080 -0.33400 0.06860
motif12.motif.bed TEAD2(TEA) 68 0.000323 -0.25200 0.00548
motif4.motif.bed GRE(NR),IR3 32 0.061100 -0.19100 0.25000
motif8.motif.bed TEAD4(TEA) 32 0.061100 -0.19100 0.25000
motif17.motif.bed TEAD(TEA) 21 0.172000 0.17200 0.37200
motif5.motif.bed Six1(Homeobox) 21 0.203000 0.16000 0.38400
motif3.motif.bed GRE(NR),IR3 34 0.175000 -0.13400 0.37200
motif1.motif.bed Six2(Homeobox) 92 0.073600 0.10800 0.25000
motif14.motif.bed Six4(Homeobox) 114 0.108000 -0.08710 0.30700
motif11.motif.bed Atf1(bZIP) 22 0.487000 0.08560 0.55200
motif10.motif.bed Mef2a(MADS) 51 0.361000 0.07390 0.51200
motif19.motif.bed TGA1(bZIP) 66 0.438000 -0.05530 0.53700
motif23.motif.bed bZIP50(bZIP) 70 0.443000 -0.05310 0.53700
motif2.motif.bed PGR(NR) 186 0.332000 0.04130 0.51200
motif20.motif.bed Atf2(bZIP) 337 0.308000 -0.03240 0.51200
motif6.motif.bed ARE(NR) 73 0.778000 0.01910 0.82700
motif7.motif.bed NF1-halfsite(CTF) 537 0.926000 -0.00236 0.92600



Detailed Gene set reports



motif21.motif.bed_PR(NR)

motif21.motif.bed_PR(NR)
9
set motif21.motif.bed_PR(NR)
setSize 21
pANOVA 0.00808
s.dist -0.334
p.adjustANOVA 0.0686



Top enriched genes

Top 20 genes
GeneID Gene Rank
Retsat -7764
St3gal5 -7383
Atoh8 -6963
Mat2a -6519
Gm20536 -6458
Reep1 -6197
Tmem56 -5947
Immt -4126
Tgoln1 -3929
Ptcd3 -3545
Vamp5 -3116
0610030E20Rik -2346
Rwdd3 -2244
Ggcx -1713
Alg14 -1192
Usp39 -393
Tmem150a 245
Polr1a 793
Rnf181 4689
Capg 6403

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
Retsat -7764
St3gal5 -7383
Atoh8 -6963
Mat2a -6519
Gm20536 -6458
Reep1 -6197
Tmem56 -5947
Immt -4126
Tgoln1 -3929
Ptcd3 -3545
Vamp5 -3116
0610030E20Rik -2346
Rwdd3 -2244
Ggcx -1713
Alg14 -1192
Usp39 -393
Tmem150a 245
Polr1a 793
Rnf181 4689
Capg 6403
Vamp8 6635



motif12.motif.bed_TEAD2(TEA)

motif12.motif.bed_TEAD2(TEA)
3
set motif12.motif.bed_TEAD2(TEA)
setSize 68
pANOVA 0.000323
s.dist -0.252
p.adjustANOVA 0.00548



Top enriched genes

Top 20 genes
GeneID Gene Rank
Gm10638 -7882
Tirap -7629
Siah1a -7569
Srpr -7080
Lonp2 -6982
Pus3 -6908
Txndc11 -6367
Trdn -6270
2210408I21Rik -6140
Foxred1 -6119
Gcnt2 -5931
Dcps -5773
Sparcl1 -5680
Trim23 -5677
2610020C07Rik -5630
Dexi -5620
Lrp10 -5377
Impact -5346
Rars2 -5161
Tmem14c -5047

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
Gm10638 -7882
Tirap -7629
Siah1a -7569
Srpr -7080
Lonp2 -6982
Pus3 -6908
Txndc11 -6367
Trdn -6270
2210408I21Rik -6140
Foxred1 -6119
Gcnt2 -5931
Dcps -5773
Sparcl1 -5680
Trim23 -5677
2610020C07Rik -5630
Dexi -5620
Lrp10 -5377
Impact -5346
Rars2 -5161
Tmem14c -5047
Fam118b -5016
Srek1ip1 -4933
Ppwd1 -4887
Akirin2 -4869
Rab10 -4669
Asxl2 -4385
Hyls1 -4366
Abhd4 -4217
Gspt1 -3570
4930581F22Rik -3519
Zfp292 -3483
Rsl1d1 -3419
A730081D07Rik -3254
Orc3 -3057
Fam172a -3051
N4bp1 -2785
Nkain2 -2754
4931414P19Rik -2740
Kif3c -1966
Nudt9 -1680
Slc35a1 -1242
Adamts6 -930
Osbpl1a -863
Dtnb -785
1110002L01Rik -457
Rps13 -141
Rpusd4 195
Aff1 390
Pate2 1207
Hsd17b11 1313
Mrpl52 1342
Dad1 1496
Cabyr 1561
Snx29 2212
Snn 2365
Klhl8 2677
Pak1ip1 3463
Zc3h7a 3593
Gm10800 4026
Gm10801 4774
4930509G22Rik 4864
Cenpk 5075
Ttc39c 5116
Cdon 5397
St3gal4 6688
Anxa2 7257
Litaf 8272
Socs1 8518



motif4.motif.bed_GRE(NR),IR3

motif4.motif.bed_GRE(NR),IR3
13
set motif4.motif.bed_GRE(NR),IR3
setSize 32
pANOVA 0.0611
s.dist -0.191
p.adjustANOVA 0.25



Top enriched genes

Top 20 genes
GeneID Gene Rank
Tirap -7629
Srpr -7080
Pus3 -6908
Txndc11 -6367
2210408I21Rik -6140
Foxred1 -6119
Dcps -5773
2610020C07Rik -5630
Dexi -5620
Fam118b -5016
Rab10 -4669
Asxl2 -4385
Hyls1 -4366
Gspt1 -3570
4930581F22Rik -3519
Rsl1d1 -3419
Fam172a -3051
Kif3c -1966
Dtnb -785
1110002L01Rik -457

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
Tirap -7629
Srpr -7080
Pus3 -6908
Txndc11 -6367
2210408I21Rik -6140
Foxred1 -6119
Dcps -5773
2610020C07Rik -5630
Dexi -5620
Fam118b -5016
Rab10 -4669
Asxl2 -4385
Hyls1 -4366
Gspt1 -3570
4930581F22Rik -3519
Rsl1d1 -3419
Fam172a -3051
Kif3c -1966
Dtnb -785
1110002L01Rik -457
Rpusd4 195
Pate2 1207
Snx29 2212
Snn 2365
Zc3h7a 3593
Gm10800 4026
Gm10801 4774
4930509G22Rik 4864
Cdon 5397
St3gal4 6688
Litaf 8272
Socs1 8518



motif8.motif.bed_TEAD4(TEA)

motif8.motif.bed_TEAD4(TEA)
17
set motif8.motif.bed_TEAD4(TEA)
setSize 32
pANOVA 0.0611
s.dist -0.191
p.adjustANOVA 0.25



Top enriched genes

Top 20 genes
GeneID Gene Rank
Tirap -7629
Srpr -7080
Pus3 -6908
Txndc11 -6367
2210408I21Rik -6140
Foxred1 -6119
Dcps -5773
2610020C07Rik -5630
Dexi -5620
Fam118b -5016
Rab10 -4669
Asxl2 -4385
Hyls1 -4366
Gspt1 -3570
4930581F22Rik -3519
Rsl1d1 -3419
Fam172a -3051
Kif3c -1966
Dtnb -785
1110002L01Rik -457

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
Tirap -7629
Srpr -7080
Pus3 -6908
Txndc11 -6367
2210408I21Rik -6140
Foxred1 -6119
Dcps -5773
2610020C07Rik -5630
Dexi -5620
Fam118b -5016
Rab10 -4669
Asxl2 -4385
Hyls1 -4366
Gspt1 -3570
4930581F22Rik -3519
Rsl1d1 -3419
Fam172a -3051
Kif3c -1966
Dtnb -785
1110002L01Rik -457
Rpusd4 195
Pate2 1207
Snx29 2212
Snn 2365
Zc3h7a 3593
Gm10800 4026
Gm10801 4774
4930509G22Rik 4864
Cdon 5397
St3gal4 6688
Litaf 8272
Socs1 8518



motif17.motif.bed_TEAD(TEA)

motif17.motif.bed_TEAD(TEA)
5
set motif17.motif.bed_TEAD(TEA)
setSize 21
pANOVA 0.172
s.dist 0.172
p.adjustANOVA 0.372



Top enriched genes

Top 20 genes
GeneID Gene Rank
Arrb1 7285
Rab3d 6433
Cebpa 6227
Rps3 5418
Ccdc159 5171
Rhpn2 4748
Gpatch1 2843
Prkcsh 2690
Dgat2 2511
Rgl3 2194
Tmem205 2177
Spcs2 2008
Gm15635 1864
Neu3 1402
Gdpd5 -32
Rnf169 -1127
Serpinh1 -2690
Ecsit -2809
Kank2 -3074
Ankrd27 -3463

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
Arrb1 7285
Rab3d 6433
Cebpa 6227
Rps3 5418
Ccdc159 5171
Rhpn2 4748
Gpatch1 2843
Prkcsh 2690
Dgat2 2511
Rgl3 2194
Tmem205 2177
Spcs2 2008
Gm15635 1864
Neu3 1402
Gdpd5 -32
Rnf169 -1127
Serpinh1 -2690
Ecsit -2809
Kank2 -3074
Ankrd27 -3463
Pdcd5 -3624



motif5.motif.bed_Six1(Homeobox)

motif5.motif.bed_Six1(Homeobox)
14
set motif5.motif.bed_Six1(Homeobox)
setSize 21
pANOVA 0.203
s.dist 0.16
p.adjustANOVA 0.384



Top enriched genes

Top 20 genes
GeneID Gene Rank
Socs1 8518
Litaf 8272
Chl1 7175
Pak3 6646
Dpy19l1 6161
Capn6 5034
4930509G22Rik 4864
Gm10801 4774
Gm10800 4026
Chrdl1 3893
Zc3h7a 3593
Snn 2365
Snx29 2212
Tpm3 351
Fam172a -3051
Rsl1d1 -3419
Gspt1 -3570
Dexi -5620
2610020C07Rik -5630
2210408I21Rik -6140

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
Socs1 8518
Litaf 8272
Chl1 7175
Pak3 6646
Dpy19l1 6161
Capn6 5034
4930509G22Rik 4864
Gm10801 4774
Gm10800 4026
Chrdl1 3893
Zc3h7a 3593
Snn 2365
Snx29 2212
Tpm3 351
Fam172a -3051
Rsl1d1 -3419
Gspt1 -3570
Dexi -5620
2610020C07Rik -5630
2210408I21Rik -6140
Txndc11 -6367



motif3.motif.bed_GRE(NR),IR3

motif3.motif.bed_GRE(NR),IR3
12
set motif3.motif.bed_GRE(NR),IR3
setSize 34
pANOVA 0.175
s.dist -0.134
p.adjustANOVA 0.372



Top enriched genes

Top 20 genes
GeneID Gene Rank
Tirap -7629
Srpr -7080
Pus3 -6908
Txndc11 -6367
2210408I21Rik -6140
Foxred1 -6119
Dcps -5773
2610020C07Rik -5630
Dexi -5620
Fam118b -5016
Rab10 -4669
Asxl2 -4385
Hyls1 -4366
Gspt1 -3570
4930581F22Rik -3519
Rsl1d1 -3419
Fam172a -3051
Kif3c -1966
Dtnb -785
1110002L01Rik -457

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
Tirap -7629
Srpr -7080
Pus3 -6908
Txndc11 -6367
2210408I21Rik -6140
Foxred1 -6119
Dcps -5773
2610020C07Rik -5630
Dexi -5620
Fam118b -5016
Rab10 -4669
Asxl2 -4385
Hyls1 -4366
Gspt1 -3570
4930581F22Rik -3519
Rsl1d1 -3419
Fam172a -3051
Kif3c -1966
Dtnb -785
1110002L01Rik -457
Rpusd4 195
Pate2 1207
Snx29 2212
Snn 2365
Zc3h7a 3593
Gm10800 4026
Gm10801 4774
4930509G22Rik 4864
Cdon 5397
Dpy19l1 6161
St3gal4 6688
Chl1 7175
Litaf 8272
Socs1 8518



motif1.motif.bed_Six2(Homeobox)

motif1.motif.bed_Six2(Homeobox)
7
set motif1.motif.bed_Six2(Homeobox)
setSize 92
pANOVA 0.0736
s.dist 0.108
p.adjustANOVA 0.25



Top enriched genes

Top 20 genes
GeneID Gene Rank
Fcho1 8327
Il27ra 8151
Bst2 8143
Ankle1 7885
Plk2 7884
Pear1 7828
Asf1b 7524
Lama1 7435
Flt3 7217
Chaf1b 7216
Jak3 7053
B3gnt3 6926
Kirrel 6864
Samd1 6304
Igsf9b 6207
Flt1 6192
N4bp3 5986
Wasf3 5902
Pomp 5772
Ddx39 5573

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
Fcho1 8327
Il27ra 8151
Bst2 8143
Ankle1 7885
Plk2 7884
Pear1 7828
Asf1b 7524
Lama1 7435
Flt3 7217
Chaf1b 7216
Jak3 7053
B3gnt3 6926
Kirrel 6864
Samd1 6304
Igsf9b 6207
Flt1 6192
N4bp3 5986
Wasf3 5902
Pomp 5772
Ddx39 5573
Plvap 5486
Dcaf15 5444
Unc13a 5368
Slc27a1 5338
Rpl35 5217
Scn1a 5146
A930012O16Rik 5124
Nhp2 4963
Pkn1 4870
Ano8 4765
Cd1d1 4755
Fcrls 4722
Setd4 4528
Etv3 4485
Nr2f6 4413
Gipc1 4386
Rfx1 4129
Hnrnpab 4019
Usp12 3690
Kat2b 3640
Sim2 3565
Cdk8 3025
Rmnd5b 2693
Fam129c 1869
1700067K01Rik 1644
Haus8 1573
Ptger1 1519
Gtpbp3 1424
Mtus2 1304
Ushbp1 844
Tecr 764
Myo9b 713
Gtf3a 136
Use1 -64
Pitx2 -228
Papola -300
Ndufb7 -319
Dda1 -591
Jam3 -924
Rpl21 -999
Prkaca -1483
0610009B22Rik -1700
Atg2b -1875
BC049762 -1972
Scoc -2669
Morc3 -2871
Sar1b -3102
Thyn1 -3198
Lnx2 -3264
Gpd2 -3314
Pgls -3403
Rab5a -3537
Clk4 -3607
Mtif3 -3958
Pan3 -4365
Zwint -4477
Acad8 -4566
Arhgef11 -4605
Galnt3 -4653
Gm10643 -4724
Vps26b -4792
Ncapd3 -4947
Abhd8 -5140
Mrpl34 -5689
Gm10644 -6677
Ocel1 -6717
Sec24a -6739
Dnajb1 -6836
Slc46a3 -6931
Ttc21b -6959
Cbr1 -7053
2210011C24Rik -7258



motif14.motif.bed_Six4(Homeobox)

motif14.motif.bed_Six4(Homeobox)
4
set motif14.motif.bed_Six4(Homeobox)
setSize 114
pANOVA 0.108
s.dist -0.0871
p.adjustANOVA 0.307



Top enriched genes

Top 20 genes
GeneID Gene Rank
Fgf1 -7869
Nrip1 -7753
Pdlim5 -7702
Ppp2r2d -7590
Snrpd3 -7537
Tsc22d3 -7527
Bnip3 -7509
Adamts2 -7507
Isy1 -7483
Zfp354b -7473
Rpn1 -7450
C030037D09Rik -7182
Hsp90b1 -7149
Rab7 -7061
Zfp454 -7057
Prkce -6989
Pdhb -6889
Stab2 -6788
Chchd10 -6570
Max -6319

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
Fgf1 -7869
Nrip1 -7753
Pdlim5 -7702
Ppp2r2d -7590
Snrpd3 -7537
Tsc22d3 -7527
Bnip3 -7509
Adamts2 -7507
Isy1 -7483
Zfp354b -7473
Rpn1 -7450
C030037D09Rik -7182
Hsp90b1 -7149
Rab7 -7061
Zfp454 -7057
Prkce -6989
Pdhb -6889
Stab2 -6788
Chchd10 -6570
Max -6319
Sorl1 -6136
Pwwp2b -6023
Zfp2 -5710
Mif -5513
Mapk1ip1 -5420
Arhgap26 -5223
Mid2 -4886
Fut8 -4791
Plbd2 -4438
Vezf1 -4043
Prps1 -4013
Rpp14 -3861
Lrrc27 -3797
Zfp879 -3731
Zfp354c -3671
Twsg1 -3560
Hdac4 -3558
Ndufa10 -3455
Stam -3434
Maml1 -3222
Ccdc122 -2988
Sc5d -2692
Gm16268 -2431
Smarcb1 -2301
Nt5dc3 -2100
Rufy1 -2067
Gnpda1 -2005
Specc1l -1942
Cnbp -1910
Gm15893 -1858
Srsf1 -1745
Pxk -1675
Ndufv2 -1654
Inpp5a -1513
Bmpr1b -1497
1810014B01Rik -1408
Ndfip1 -1095
Tbc1d9b -1085
Msi2 -953
Vapa -715
Srbd1 -559
Rnf14 -436
Hnrnph1 -195
Slc39a12 97
Mmp11 99
Gm5577 227
Sdsl 289
Gtf2b 376
Fntb 520
Sec61a1 958
Ralbp1 1114
Fabp3 1214
Mgat4b 1530
Ppp4r1 1816
Abhd6 2043
Cabin1 2195
Canx 2201
Tmem232 2385
Rab15 2639
Tpcn1 2764
Sqstm1 3601
Tsc22d1 3673
Cacnb2 3832
Jakmip3 3877
Mrps23 3974
Gfra1 4093
Dmrta2 4137
Susd2 4258
Dynll2 4337
Twist2 4423
Cdkn2c 4463
Gpc6 4834
Rbm19 4851
Tbcel 5151
Tecta 5247
Gstt1 5293
Ddx54 5666
Spry4 5938
Gstt2 6093
Timp3 6221
Rps19 6260
Flnb 6745
Ggt5 6924
Mrc1 7047
Rab31 7168
Plekhg3 7197
Adora2a 7665
Gbp7 8432
Oas1b 8442
Gbp2 8455
Oas3 8459
Oas2 8500
Gbp5 8510
Gbp3 8511



motif11.motif.bed_Atf1(bZIP)

motif11.motif.bed_Atf1(bZIP)
2
set motif11.motif.bed_Atf1(bZIP)
setSize 22
pANOVA 0.487
s.dist 0.0856
p.adjustANOVA 0.552



Top enriched genes

Top 20 genes
GeneID Gene Rank
Socs1 8518
Litaf 8272
Chl1 7175
Pak3 6646
Dpy19l1 6161
Capn6 5034
4930509G22Rik 4864
Chrdl1 3893
Zc3h7a 3593
Snn 2365
Snx29 2212
Tpm3 351
1110002L01Rik -457
Dtnb -785
Kif3c -1966
Rsl1d1 -3419
Gspt1 -3570
Asxl2 -4385
Rab10 -4669
Dexi -5620

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
Socs1 8518
Litaf 8272
Chl1 7175
Pak3 6646
Dpy19l1 6161
Capn6 5034
4930509G22Rik 4864
Chrdl1 3893
Zc3h7a 3593
Snn 2365
Snx29 2212
Tpm3 351
1110002L01Rik -457
Dtnb -785
Kif3c -1966
Rsl1d1 -3419
Gspt1 -3570
Asxl2 -4385
Rab10 -4669
Dexi -5620
2610020C07Rik -5630
Txndc11 -6367



motif10.motif.bed_Mef2a(MADS)

motif10.motif.bed_Mef2a(MADS)
1
set motif10.motif.bed_Mef2a(MADS)
setSize 51
pANOVA 0.361
s.dist 0.0739
p.adjustANOVA 0.512



Top enriched genes

Top 20 genes
GeneID Gene Rank
AB124611 8213
S1pr2 8016
Cdc7 7456
Chl1 7175
Pak3 6646
Zbtb7c 6417
Dpy19l1 6161
Kri1 6112
Qtrt1 5135
Capn6 5034
Gm10801 4774
Tyk2 4736
Slc44a2 4542
Rassf3 4476
Cyp2j9 4307
Srgap1 4197
Gm10800 4026
Chrdl1 3893
Jakmip3 3877
Rap2a 3794

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
AB124611 8213
S1pr2 8016
Cdc7 7456
Chl1 7175
Pak3 6646
Zbtb7c 6417
Dpy19l1 6161
Kri1 6112
Qtrt1 5135
Capn6 5034
Gm10801 4774
Tyk2 4736
Slc44a2 4542
Rassf3 4476
Cyp2j9 4307
Srgap1 4197
Gm10800 4026
Chrdl1 3893
Jakmip3 3877
Rap2a 3794
Smad7 3695
Smarca4 3588
Cdkn2d 2638
Tbk1 2550
BC048403 2465
Carm1 2356
Gm20544 2282
Ilf3 2169
Keap1 1254
Dnm2 365
Yipf2 -220
Gm20519 -397
Gns -482
Cdc37 -1482
Inpp5a -1513
Tgfbr3 -1600
Brdt -2040
Xpot -2331
Ctif -2440
Lrrc27 -3797
1700084C06Rik -4248
Atg4d -5251
Pde4a -5350
Mapk1ip1 -5420
Pwwp2b -6023
Tmed1 -6042
Cyp2j6 -6377
Bnip3 -7509
Ppp2r2d -7590
Mbnl2 -7840
Sgk1 -7848



motif19.motif.bed_TGA1(bZIP)

motif19.motif.bed_TGA1(bZIP)
6
set motif19.motif.bed_TGA1(bZIP)
setSize 66
pANOVA 0.438
s.dist -0.0553
p.adjustANOVA 0.537



Top enriched genes

Top 20 genes
GeneID Gene Rank
St3gal5 -7383
Krcc1 -6529
Hoxa13 -6426
Reep1 -6197
Hoxa2 -5923
Nadk -5907
Trim23 -5677
Mecr -5532
Snhg12 -5514
Slc35e2 -5303
Taf12 -5082
Srek1ip1 -4933
Ppwd1 -4887
5830444B04Rik -4774
Mrpl35 -4628
Gm16023 -4277
Immt -4126
Ptcd3 -3545
Aurkaip1 -2930
Rmnd5a -2767

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
St3gal5 -7383
Krcc1 -6529
Hoxa13 -6426
Reep1 -6197
Hoxa2 -5923
Nadk -5907
Trim23 -5677
Mecr -5532
Snhg12 -5514
Slc35e2 -5303
Taf12 -5082
Srek1ip1 -4933
Ppwd1 -4887
5830444B04Rik -4774
Mrpl35 -4628
Gm16023 -4277
Immt -4126
Ptcd3 -3545
Aurkaip1 -2930
Rmnd5a -2767
Hibadh -2756
Eya3 -2525
Gm10300 -2514
Hoxa7 -2382
Kdm3a -2267
Hoxa11 -1878
Mxra8 -1776
Ythdf2 -1367
Ccnl2 -1109
Adamts6 -930
Ssu72 -788
Dnajc8 -631
Chmp3 -422
Hoxa10 345
Rnf103 373
Prkcz 477
Mrpl20 552
Polr1a 793
Med18 1211
Phactr4 1457
Dvl1 1480
Mib2 1702
Srsf4 1725
Gm17300 1762
Rer1 1769
Rpa2 1968
Gnb1 2048
Ski 3080
Sesn2 3418
Rps15a 3605
Vwa1 4090
Rcc1 4212
Ptpru 4313
Gm10563 4384
Hoxa9 4502
Trnau1ap 4605
Mmp23 4977
Gmeb1 4997
Cenpk 5075
Tmem88b 5099
Smyd1 5380
Gm12992 5563
Oprd1 6761
Atpif1 6950
Skap2 7471
Cd8a 7985



motif23.motif.bed_bZIP50(bZIP)

motif23.motif.bed_bZIP50(bZIP)
10
set motif23.motif.bed_bZIP50(bZIP)
setSize 70
pANOVA 0.443
s.dist -0.0531
p.adjustANOVA 0.537



Top enriched genes

Top 20 genes
GeneID Gene Rank
Gm15337 -7904
Fgf1 -7869
Nr3c1 -7849
Tmem52 -7766
Zcchc2 -7472
Fbxw7 -7270
Lmbrd1 -6875
B3galt6 -6828
Max -6319
Nadk -5907
Ehd3 -5785
Pign -5572
Slc35e2 -5303
Fut8 -4791
5830444B04Rik -4774
Memo1 -4465
Gm15336 -4354
Gm16023 -4277
Atad3a -4122
Tas1r3 -3259

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
Gm15337 -7904
Fgf1 -7869
Nr3c1 -7849
Tmem52 -7766
Zcchc2 -7472
Fbxw7 -7270
Lmbrd1 -6875
B3galt6 -6828
Max -6319
Nadk -5907
Ehd3 -5785
Pign -5572
Slc35e2 -5303
Fut8 -4791
5830444B04Rik -4774
Memo1 -4465
Gm15336 -4354
Gm16023 -4277
Atad3a -4122
Tas1r3 -3259
Aurkaip1 -2930
Yipf4 -2766
Kcnb1 -2412
Cse1l -2306
Mxra8 -1776
Spast -1392
1110018N20Rik -1262
Ccnl2 -1109
Btg3 -983
Cxadr -890
Pusl1 -807
Phlpp1 -791
Ssu72 -788
Chodl -763
Ppie -721
Arfgef2 -574
Sdf4 -328
Pabpc4 -317
Nt5c1a 106
Fntb 520
Mrpl20 552
Dvl1 1480
Mib2 1702
Rer1 1769
Gnb1 2048
Rab15 2639
Gm10925 2878
Stau1 2936
Slc9a8 2984
Ski 3080
Ube2j2 3163
Dpy30 3302
D16Ertd472e 3815
B4galt5 3890
Znfx1 3919
Rnf114 4088
Vwa1 4090
Ptgis 4618
Mmp23 4977
Ddx27 5197
Cdk11b 5337
Acap3 5876
Col19a1 5889
Snai1 6027
Heyl 6090
Plekhg3 7197
Prex1 7451
Tnfrsf11a 8341
Xdh 8353
Galnt14 8482



motif2.motif.bed_PGR(NR)

motif2.motif.bed_PGR(NR)
11
set motif2.motif.bed_PGR(NR)
setSize 186
pANOVA 0.332
s.dist 0.0413
p.adjustANOVA 0.512



Top enriched genes

Top 20 genes
GeneID Gene Rank
Icam1 8422
AB124611 8213
Ptprj 8187
Plcg2 8076
S1pr2 8016
Hmga2 7923
Crlf2 7868
Bub1b 7776
Thbs1 7600
Gpr176 7491
Lmo2 7432
Chaf1b 7216
Edem1 7208
Rab31 7168
Tiam2 7160
Gm12610 6978
Ephb3 6921
Krt7 6899
Gm13986 6867
Acvrl1 6799

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
Icam1 8422
AB124611 8213
Ptprj 8187
Plcg2 8076
S1pr2 8016
Hmga2 7923
Crlf2 7868
Bub1b 7776
Thbs1 7600
Gpr176 7491
Lmo2 7432
Chaf1b 7216
Edem1 7208
Rab31 7168
Tiam2 7160
Gm12610 6978
Ephb3 6921
Krt7 6899
Gm13986 6867
Acvrl1 6799
Tubb6 6754
Mppe1 6742
Mylip 6618
Gm14548 6400
Krt80 6376
Impa2 6238
Kri1 6112
Pkd1l2 6063
Def6 5951
Mybpc3 5693
Bdh2 5324
4632428C04Rik 5317
Cacng7 5297
Dna2 5263
Nr4a1 5158
Qtrt1 5135
Spp1 5109
Sdr42e1 4996
Tyk2 4736
Gan 4732
Slc44a2 4542
Setd4 4528
Rassf3 4476
Cdkn2c 4463
Sh3bgrl2 4429
Rps9 4391
Fance 4301
Tead3 4278
Hes1 4214
Srgap1 4197
Dmrta2 4137
Hnrnph3 4030
Rpl10a 3972
Bmf 3930
Tfpt 3796
Cnot3 3766
Arl8b 3688
Smarca4 3588
Mphosph6 3393
Ap2m1 3370
Pacsin3 3360
Srpk1 3349
Celf1 3296
Abcf3 3199
Mtap 3138
B430212C06Rik 3089
Nat10 3056
Klhl8 2677
Cdkn2d 2638
Cdkn2b 2562
Gm17055 2560
Tbk1 2550
Prpf31 2541
BC048403 2465
Tmem232 2385
Carm1 2356
Tmc4 2347
Leng1 2216
Ilf3 2169
Tomm7 2150
6030408B16Rik 2129
A930018P22Rik 1899
Grasp 1845
Ppp4r1 1816
Cenpn 1802
Gnal 1463
Dtnbp1 1314
Hsd17b11 1313
Zfp523 1275
Keap1 1254
Ralbp1 1114
Agbl2 1080
Pisd 969
Lemd3 954
Mrpl4 943
Caprin1 766
Srp14 464
Aff1 390
Dnm2 365
Ddx21 239
Gmpr 237
Sumf1 148
Slc25a16 3
Pkd2 -46
Rpl30 -136
Vps8 -190
Yipf2 -220
D930016D06Rik -267
Manba -280
Gm20519 -397
Ivd -435
Nfkb1 -466
Gns -482
Mapk14 -622
Alg3 -697
Vapa -715
Brpf3 -749
Fnbp4 -909
Usp27x -1309
Gm15927 -1372
Chst14 -1398
Cdc37 -1482
Ndufv2 -1654
Mboat7 -1663
Nudt9 -1680
Ssb -1695
Cd59a -1838
Plp2 -1843
Tsen34 -1850
Srpk2 -1940
Ptpmt1 -2099
Xpot -2331
Ubr3 -2393
Gcsh -2458
Pus7 -2511
Eif2ak4 -2659
4930522L14Rik -2680
Morc3 -2871
Ppard -2973
Oscar -3052
Scaf8 -3203
Slc39a8 -3336
Atmin -3414
Twsg1 -3560
Ccar1 -3622
Afg3l2 -3703
Nup160 -3894
Gm15446 -4107
Herc4 -4190
1700084C06Rik -4248
Ndufs3 -4432
Ndufa3 -4519
Cisd2 -4677
Rufy2 -4700
Mettl5 -4756
Fbxo3 -4848
Mypn -4967
5031425E22Rik -4986
Cd59b -5003
Atg4d -5251
Pde4a -5350
Ube2d3 -5385
Tfb1m -5648
Sparcl1 -5680
Acvr1b -5770
Gm17661 -5790
Pbld1 -5874
C1qtnf4 -6009
Tmed1 -6042
Bhlhe40 -6098
Cidea -6116
Phospho2 -6123
Tet1 -6217
Amot -6356
Ddx50 -6358
Gm10912 -6394
Mtch2 -6618
Ppig -6670
BC005561 -6680
Kbtbd4 -6738
Cbr1 -7053
Msrb3 -7191
5430403G16Rik -7243
Fkbp5 -7491
0610040F04Rik -7644
D430041D05Rik -7701



motif20.motif.bed_Atf2(bZIP)

motif20.motif.bed_Atf2(bZIP)
8
set motif20.motif.bed_Atf2(bZIP)
setSize 337
pANOVA 0.308
s.dist -0.0324
p.adjustANOVA 0.512



Top enriched genes

Top 20 genes
GeneID Gene Rank
Fgf1 -7869
Ell2 -7839
Stbd1 -7782
Tmem52 -7766
Retsat -7764
Nrip1 -7753
Crim1 -7734
Pdlim5 -7702
D430041D05Rik -7701
Ppp2r2d -7590
Bnip3 -7509
Adamts2 -7507
Zfp354b -7473
Art3 -7412
Rfesd -7399
St3gal5 -7383
1300017J02Rik -7344
Hyal1 -7306
Gm9917 -7292
Arrdc2 -7211

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
Fgf1 -7869
Ell2 -7839
Stbd1 -7782
Tmem52 -7766
Retsat -7764
Nrip1 -7753
Crim1 -7734
Pdlim5 -7702
D430041D05Rik -7701
Ppp2r2d -7590
Bnip3 -7509
Adamts2 -7507
Zfp354b -7473
Art3 -7412
Rfesd -7399
St3gal5 -7383
1300017J02Rik -7344
Hyal1 -7306
Gm9917 -7292
Arrdc2 -7211
Ghr -7193
Glul -7169
Hsp90b1 -7149
Egln3 -7060
Oxct1 -7058
Zfp454 -7057
Scarb2 -7035
Atoh8 -6963
5830418P13Rik -6953
B3galt6 -6828
Gm15564 -6823
Stab2 -6788
Tcp11l2 -6786
Srprb -6712
Gpc1 -6707
Tmem115 -6705
Yipf6 -6543
Trim67 -6542
Ccdc152 -6535
Klf6 -6527
Mat2a -6519
Gm20536 -6458
Cdv3 -6443
Gm10912 -6394
Cyp2j6 -6377
Hemk1 -6339
Max -6319
Mpv17l2 -6282
Ier3 -6278
Kpna1 -6271
Trdn -6270
Nuak1 -6225
AW549877 -6216
Reep1 -6197
Med21 -6181
Wdr5b -6068
Pwwp2b -6023
Nadk -5907
Ttc13 -5902
Cacna2d2 -5864
Iars -5737
Zfp2 -5710
Sparcl1 -5680
Shroom3 -5611
Mavs -5467
Rab3a -5439
Mapk1ip1 -5420
Hyal2 -5387
Slc35e2 -5303
Arhgap26 -5223
Fam162a -5135
Mysm1 -5018
Cd59b -5003
Mrps35 -4850
Fbxo3 -4848
Fut8 -4791
5830444B04Rik -4774
Mapkapk3 -4731
Wnk2 -4718
Arhgef11 -4605
Pnkd -4494
Nprl2 -4447
Plbd2 -4438
Tpt1 -4379
Gm16023 -4277
Gm17040 -4244
Jun -4145
Immt -4126
Atad3a -4122
Rbm5 -4114
Glrx -4069
2310015A10Rik -4000
Tgoln1 -3929
Hyal3 -3803
Lrrc27 -3797
Ttc37 -3733
Zfp879 -3731
Stk38l -3694
Zfp354c -3671
Hdac4 -3558
Ptcd3 -3545
Ndufa10 -3455
Stam -3434
Rgsl1 -3405
Ddr1 -3371
Tas1r3 -3259
Maml1 -3222
Vamp5 -3116
Ccdc58 -2978
Aurkaip1 -2930
Polr3b -2896
Ccni -2877
Sec22a -2790
Slc25a30 -2760
Nkain2 -2754
Cish -2749
Rpl36 -2724
Pde4c -2654
Fez2 -2642
Rab6b -2614
Zmynd10 -2521
Gm16268 -2431
Arntl2 -2414
Ogn -2395
0610030E20Rik -2346
Stard8 -2260
Cyb561d2 -2214
Nol8 -2144
Gm10654 -2118
Nt5dc3 -2100
Rufy1 -2067
Gnpda1 -2005
2310061I04Rik -1997
Cog3 -1959
Pik3r2 -1919
Cd59a -1838
Mxra8 -1776
Ggcx -1713
Nudt9 -1680
Nae1 -1577
Inpp5a -1513
Bmpr1b -1497
Appl2 -1436
1810014B01Rik -1408
Klf10 -1395
Snrpb2 -1298
Ccnl2 -1109
Ndfip1 -1095
Tbc1d9b -1085
Kcnn1 -1061
Rpl21 -999
Snx13 -831
Pusl1 -807
Ssu72 -788
Ell -738
Ppie -721
Pgpep1 -611
Zfp36l1 -450
Rnf14 -436
Fam120a -411
Tmem161a -405
Usp39 -393
Arv1 -379
Hint1 -340
Sdf4 -328
Pabpc4 -317
Hnrnph1 -195
Fbxo4 -57
Rassf1 41
Car7 74
Slc39a12 97
Nt5c1a 106
Dirc2 144
Tmem150a 245
Ubr5 256
Sdsl 289
Gtf2b 376
Azin1 391
Gpx3 425
Fntb 520
Cdh5 549
Mrpl20 552
Rpl18a 687
Eapp 703
Caprin1 766
Polr1a 793
Tusc2 796
Dync1li2 873
Gm14233 891
Gtf2h4 1069
Ctdsp1 1083
Kif16b 1124
Hspbap1 1162
Flot1 1164
Fabp3 1214
Hsd17b11 1313
Bicd2 1358
Sept11 1470
Dvl1 1480
Mgat4b 1530
Ccdc124 1620
Cog2 1679
Mib2 1702
Rer1 1769
A930018P22Rik 1899
Aspn 1928
Slc38a3 1985
Gnb1 2048
Klhl26 2180
Canx 2201
Pgbd5 2301
2310022B05Rik 2406
Rep15 2548
Cope 2549
Atp6v1c1 2602
Rab15 2639
Klhl8 2677
Agt 2763
Tpcn1 2764
1700037H04Rik 2774
Slc36a1 2799
Tns1 2906
Nufip1 2915
Ccng2 2967
Ippk 3006
Ifrd2 3013
Ddx49 3020
Nat10 3056
Ski 3080
Ube2j2 3163
Ecm2 3364
Sqstm1 3601
Upf1 3703
Cacnb2 3832
Rhobtb3 3868
Jakmip3 3877
Dock3 3892
Phf2 3899
Gm11175 3961
Vwa1 4090
Efnb1 4152
Slc36a2 4161
Tmbim1 4244
Cyp2j9 4307
Jund 4326
Vars2 4339
Topbp1 4383
Twist2 4423
Anxa6 4425
Xylb 4451
Etv3 4485
Cmtm4 4491
Acaa1a 4521
Slc5a5 4532
Exog 4559
Aamp 4626
Ccdc69 4633
Fkbp8 4654
Rnf181 4689
Fcrls 4722
Crtc1 4740
Cd1d1 4755
Sema3b 4799
G3bp1 4806
Sema3f 4837
Rbm19 4851
Lsm4 4920
Cklf 4967
Mmp23 4977
Spp1 5109
Arpc2 5119
Pdia5 5163
Pdp2 5214
Cdk11b 5337
Tk2 5369
Tmem108 5627
Isyna1 5631
Actn1 5657
Ddx54 5666
Nrm 5685
Spry1 5692
Mdc1 5701
Atox1 5756
Acap3 5876
Acvr2b 5900
Spry4 5938
Fzd6 5947
Mast3 5980
Rnf24 5995
Gm2a 6024
Heyl 6090
Timp3 6221
Sparc 6233
Cenpp 6254
Txn1 6285
Capg 6403
Svep1 6414
Adra1d 6469
Smox 6473
Vamp8 6635
Ppfibp1 6690
Ckap4 6772
Fat2 6788
Kirrel 6864
Ninj1 7028
Tubb5 7032
Fgd3 7038
Mrc1 7047
Rgs16 7136
Cdc25b 7165
Ifi30 7183
Plekhg3 7197
Rnasel 7384
Spef1 7400
Lmo2 7432
Ahr 7620
Parp9 7628
Naaa 7677
Cmtm3 7719
Gnai2 7725
Scn5a 7808
Pear1 7828
Ssbp4 7837
Susd3 7902
Dtx3l 8267
Il12rb1 8298
Rrad 8339
Lrrc25 8428
Gbp7 8432
Oas1b 8442
Gbp2 8455
Oas3 8459
Oas2 8500
Parp14 8506
Gbp5 8510
Gbp3 8511
Slc11a1 8515



motif6.motif.bed_ARE(NR)

motif6.motif.bed_ARE(NR)
15
set motif6.motif.bed_ARE(NR)
setSize 73
pANOVA 0.778
s.dist 0.0191
p.adjustANOVA 0.827



Top enriched genes

Top 20 genes
GeneID Gene Rank
Socs1 8518
Gbp3 8511
Gbp5 8510
Gbp2 8455
Gbp7 8432
Clec12a 8399
Litaf 8272
Clec9a 7916
BC035044 7881
Klrk1 7870
Chl1 7175
Gm15987 7171
St3gal4 6688
Pak3 6646
Cks2 6608
Clec2i 6501
Clec7a 6291
Dpy19l1 6161
Sema4d 5969
Cdon 5397

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
Socs1 8518
Gbp3 8511
Gbp5 8510
Gbp2 8455
Gbp7 8432
Clec12a 8399
Litaf 8272
Clec9a 7916
BC035044 7881
Klrk1 7870
Chl1 7175
Gm15987 7171
St3gal4 6688
Pak3 6646
Cks2 6608
Clec2i 6501
Clec7a 6291
Dpy19l1 6161
Sema4d 5969
Cdon 5397
Clec1a 5192
Capn6 5034
4930509G22Rik 4864
Gm10801 4774
Secisbp2 4568
Gm10800 4026
Chrdl1 3893
Sqstm1 3601
Zc3h7a 3593
Snn 2365
Snx29 2212
Canx 2201
Mgat4b 1530
Pate2 1207
Gtf2b 376
Rpusd4 195
Hnrnph1 -195
1110002L01Rik -457
Dtnb -785
Gadd45g -919
Tbc1d9b -1085
Bmpr1b -1497
Kif3c -1966
Rufy1 -2067
2310001H17Rik -2265
Gabarapl1 -3019
Fam172a -3051
Maml1 -3222
Rsl1d1 -3419
4930581F22Rik -3519
Gspt1 -3570
Zfp354c -3671
Zfp879 -3731
Hyls1 -4366
Asxl2 -4385
Rab10 -4669
Fam118b -5016
Dexi -5620
2610020C07Rik -5630
Zfp2 -5710
Dcps -5773
Clec2e -6031
Foxred1 -6119
2210408I21Rik -6140
Txndc11 -6367
Pus3 -6908
Zfp454 -7057
Srpr -7080
Zfp354b -7473
Adamts2 -7507
Clec2d -7559
Tirap -7629
Pdlim5 -7702



motif7.motif.bed_NF1-halfsite(CTF)

motif7.motif.bed_NF1-halfsite(CTF)
16
set motif7.motif.bed_NF1-halfsite(CTF)
setSize 537
pANOVA 0.926
s.dist -0.00236
p.adjustANOVA 0.926



Top enriched genes

Top 20 genes
GeneID Gene Rank
Htra1 -7906
Sgk1 -7848
Gm5420 -7847
Tgfb2 -7845
Mbnl2 -7840
Cntfr -7833
Slc2a3 -7813
Stbd1 -7782
Padi2 -7760
Nrip1 -7753
Crim1 -7734
Rock2 -7709
AI464131 -7651
Lyplal1 -7648
Lifr -7645
Sigmar1 -7592
Ppp2r2d -7590
Clec2d -7559
Snrpd3 -7537
Abi2 -7514

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
Htra1 -7906
Sgk1 -7848
Gm5420 -7847
Tgfb2 -7845
Mbnl2 -7840
Cntfr -7833
Slc2a3 -7813
Stbd1 -7782
Padi2 -7760
Nrip1 -7753
Crim1 -7734
Rock2 -7709
AI464131 -7651
Lyplal1 -7648
Lifr -7645
Sigmar1 -7592
Ppp2r2d -7590
Clec2d -7559
Snrpd3 -7537
Abi2 -7514
Bnip3 -7509
Fkbp5 -7491
Zcchc2 -7472
Art3 -7412
Akr1e1 -7400
Cachd1 -7386
St3gal5 -7383
Man2a1 -7350
Fbxw7 -7270
Map2k6 -7222
Lpp -7207
Egflam -7205
Ghr -7193
C030037D09Rik -7182
Glul -7169
Hsp90b1 -7149
Pm20d1 -7109
Oxct1 -7058
Cbr1 -7053
Scarb2 -7035
Smyd2 -7011
Prkce -6989
Atoh8 -6963
Gm10600 -6933
Pdhb -6889
E2f6 -6868
Rps6ka5 -6865
Enho -6847
Gm15564 -6823
Abca5 -6815
Arl15 -6794
Stab2 -6788
Tcp11l2 -6786
Hps4 -6730
Gpc1 -6707
Lrrc14b -6697
Creg1 -6687
B230354K17Rik -6653
Chchd10 -6570
Homer1 -6561
Tmed9 -6547
Pde4d -6546
Yipf6 -6543
Ccdc152 -6535
Krcc1 -6529
Sdha -6526
Txndc11 -6367
Ccl27a -6362
Grb10 -6347
Max -6319
Mpzl1 -6281
Kpna1 -6271
Trdn -6270
Tbc1d1 -6252
Tmprss5 -6229
Gm5617 -6228
Nuak1 -6225
AW549877 -6216
Zbtb16 -6213
Reep1 -6197
Med21 -6181
Slc38a6 -6151
Cops2 -6110
Bhlhe40 -6098
Asf1a -6095
Wdr5b -6068
Clec2e -6031
Pwwp2b -6023
Trmt5 -6004
Bbx -5935
B230219D22Rik -5932
Nadk -5907
Fam13c -5865
Srrd -5843
Usp37 -5800
Trim23 -5677
2610020C07Rik -5630
Dexi -5620
Shroom3 -5611
Ercc8 -5594
Pign -5572
Mif -5513
Mavs -5467
Kbtbd12 -5456
Mapk1ip1 -5420
Six4 -5388
Pln -5379
Impact -5346
Vmp1 -5343
Slc35e2 -5303
Lyrm7 -5262
Fam162a -5135
Adcy10 -5060
Ndufaf2 -5019
Mysm1 -5018
Cog1 -4968
Srek1ip1 -4933
Ppwd1 -4887
Mrps35 -4850
Fut8 -4791
Rbm7 -4787
5830444B04Rik -4774
Ptpn3 -4725
Zw10 -4692
Mrpl35 -4628
Caml -4538
Zfp622 -4514
Pnkd -4494
Gm16023 -4277
Mnat1 -4205
Cltc -4154
Jun -4145
Immt -4126
Ptrh2 -4093
Vezf1 -4043
2610035D17Rik -4027
2310015A10Rik -4000
Tgoln1 -3929
Palm2 -3891
Tubd1 -3864
Rpp14 -3861
Gdpd1 -3834
Lrrc27 -3797
Slc41a1 -3705
Stk38l -3694
Dcaf6 -3677
Cmya5 -3637
Gspt1 -3570
Hdac4 -3558
Ptcd3 -3545
Larp1b -3478
Ndufa10 -3455
Rsl1d1 -3419
Rgsl1 -3405
Necap1 -3332
Rps6kb1 -3248
Sdhb -3240
Med13 -3155
Slc35b2 -3096
Gabarapl1 -3019
Ccdc58 -2978
Btbd6 -2974
Ppard -2973
Ebf3 -2965
Hbs1l -2952
Tpst2 -2934
Aurkaip1 -2930
Polr3b -2896
Ccni -2877
Morc3 -2871
Sec22a -2790
Tbc1d12 -2782
Rmnd5a -2767
Nkain2 -2754
Rpl36 -2724
Zmiz1 -2703
Dcaf12 -2657
Fez2 -2642
Ptpn14 -2623
Srgap2 -2582
Mgll -2562
Il11ra1 -2473
Gm16268 -2431
Arntl2 -2414
Crybb1 -2307
Smarcb1 -2301
Gm15612 -2300
Kdm3a -2267
2310001H17Rik -2265
Stard8 -2260
Cdc5l -2205
Glrx3 -2141
Scaf4 -2101
Nt5dc3 -2100
Ppif -2061
Brdt -2040
Srek1 -2030
Gtf2ird2 -1996
Specc1l -1942
Gm15627 -1880
Gm15893 -1858
Nln -1839
Mxra8 -1776
Tfip11 -1754
Srsf1 -1745
Pxk -1675
Tgfbr3 -1600
Fam193b -1598
Nae1 -1577
Ubap1 -1556
B4galt7 -1547
Pgm1 -1525
Nudt2 -1517
Inpp5a -1513
Fbxo42 -1438
Stk38 -1437
Appl2 -1436
1810014B01Rik -1408
Hsp90ab1 -1405
Klf10 -1395
Gm16196 -1344
Bag1 -1120
Ccnl2 -1109
Ctnnal1 -1050
Rpl21 -999
Rpl29 -985
Btg3 -983
Msi2 -953
Pgrmc2 -947
Adamts6 -930
Dhx40 -903
Cxadr -890
Osbpl1a -863
Dctn3 -806
Phlpp1 -791
Ssu72 -788
Oxa1l -782
Chodl -763
Brpf3 -749
Slc6a18 -728
Mapk14 -622
Ruvbl1 -608
Srbd1 -559
1110017D15Rik -474
Zfp36l1 -450
Pja2 -430
Chmp3 -422
Usp39 -393
Hint1 -340
Sod1 -333
Rell1 -316
Ipo13 -315
Prr7 -181
Fbxo4 -57
6430590A07Rik -51
Rpl35a -24
Txndc15 -12
Lpin1 5
Ints2 17
Serinc5 23
Zbtb42 48
Car7 74
Mtch1 82
Mapkapk2 91
Mmp11 99
Brf1 143
Dirc2 144
Sumf1 148
Tmem150a 245
Ubr5 256
Eefsec 317
Gtf2i 319
Rnf103 373
Azin1 391
Gpx3 425
Mtx3 475
Prkcz 477
Fntb 520
Cdh5 549
Mrpl20 552
Clptm1l 566
Tmem63b 599
Dph2 619
Tex22 649
Polr1a 793
Dync1li2 873
Plekha1 880
Gm14233 891
Spats1 916
Fam72a 920
Zcchc24 951
Sec61a1 958
9430038I01Rik 1007
Srsf3 1041
Ctdsp1 1083
Ddx41 1159
Hspbap1 1162
Cep152 1181
Fabp3 1214
Ddx46 1253
Zfp523 1275
Pcbd2 1297
Lman2 1301
Rexo2 1382
Ubap2 1385
Elovl7 1398
Cyp20a1 1399
Sept11 1470
Dvl1 1480
Cabyr 1561
Tppp 1623
Pacs2 1699
Mib2 1702
Rer1 1769
Plce1 1826
Slc39a11 1868
Rnf220 1929
D11Wsu47e 1976
Abhd6 2043
Gnb1 2048
Cdca4 2063
Cabin1 2195
Snx29 2212
Sgtb 2229
Crocc 2230
Rnft1 2242
Siva1 2245
Snn 2365
Rep15 2548
Raph1 2570
Atp6v1c1 2602
Rab15 2639
Gm15912 2640
Usp28 2682
Rcc2 2741
1700037H04Rik 2774
Dnaic1 2797
Slc36a1 2799
Tns1 2906
Nufip1 2915
Hells 2923
Atp6v0b 2952
Ccng2 2967
Six1 2999
Cep72 3026
Ski 3080
Foxj2 3082
Rrp15 3162
Dut 3243
Slc6a9 3251
Sox9 3255
Dmap1 3298
Srpk1 3349
Zc3h7a 3593
Eri3 3666
Tsc22d1 3673
Pdlim7 3676
Bnc2 3721
Rap2a 3794
D16Ertd472e 3815
Tiam1 3824
Brd9 3835
Jakmip3 3877
Galk2 3878
Chrdl1 3893
Rcsd1 3940
Rab24 3952
Fbxo7 3956
Rpl10a 3972
Mrps23 3974
Tpra1 3988
Noc3l 4004
Vwa1 4090
Efnb1 4152
Slc36a2 4161
Kctd20 4229
Tmbim1 4244
Susd2 4258
Podxl2 4260
Tead3 4278
BC004004 4288
Fance 4301
Nol6 4327
Dynll2 4337
Cdc42se2 4343
Gm10563 4384
Twist2 4423
Anxa6 4425
Xylb 4451
Cmtm4 4491
Acaa1a 4521
Setd4 4528
Exog 4559
Ube2r2 4583
Tacc2 4600
Fam184a 4624
Aamp 4626
Grk6 4676
Rnf181 4689
Gtf2ird1 4710
Ypel2 4739
G3bp1 4806
4930509G22Rik 4864
Abtb1 4925
Atp13a2 4954
Cklf 4967
Mmp23 4977
Kif24 5030
Capn6 5034
Mta1 5050
Cenpk 5075
Tmem88b 5099
Ttc39c 5116
Arpc2 5119
B4galt2 5123
Pdia5 5163
Clec1a 5192
Abca6 5198
Pdp2 5214
Scube3 5245
Zpbp 5264
Gstt1 5293
Lsamp 5316
Tk2 5369
Smyd1 5380
Slc29a1 5436
Abca8a 5440
Dok3 5465
Mfap5 5474
Bcl6 5510
Mfap2 5527
Necap2 5532
Slit3 5620
Ddc 5626
Actn1 5657
Spry1 5692
Greb1 5748
Btbd16 5754
Atox1 5756
Aars2 5774
Acvr2b 5900
Fzd6 5947
Anxa11 5949
Def6 5951
Sfrp2 5965
Gm16191 5988
Rnf24 5995
Lpcat1 5997
Gm2a 6024
Zswim6 6062
Ighm 6069
Gstt2 6093
Ppil1 6116
Prelid1 6123
Nudt14 6181
Timp3 6221
Sparc 6233
Abca9 6287
Mcm9 6290
Clec7a 6291
Eid1 6345
Adra1d 6469
Smox 6473
Akt1 6491
Clec2i 6501
Crip1 6522
Emp1 6553
Fbn1 6586
Gm16029 6630
Vamp8 6635
Pak3 6646
Ppfibp1 6690
Flnb 6745
Pqlc3 6755
Ckap4 6772
Fat2 6788
Nnmt 6866
Hunk 6906
Ggt5 6924
Slc16a9 6940
Crip2 6943
Trip13 7049
Jag2 7068
Nkd2 7091
Myef2 7108
Rgs16 7136
Mcm2 7137
Cdc25b 7165
Gm15987 7171
Plekhg3 7197
Chaf1b 7216
Cntln 7231
Anxa2 7257
Dbn1 7259
Miat 7281
Fignl1 7299
Rassf5 7383
Rnasel 7384
Samsn1 7385
Spef1 7400
Ntsr2 7425
Cdc42ep4 7436
Cdc7 7456
Ahnak2 7462
Clec4a3 7571
Parp9 7628
Adora2a 7665
Naaa 7677
Slc12a7 7688
Inf2 7716
Cmtm3 7719
Tlr2 7767
Scn5a 7808
Clec4a4 7859
Klrk1 7870
BC035044 7881
Gpr132 7899
Clec9a 7916
Cd8a 7985
Pld4 8146
C3ar1 8160
Apobec1 8204
Cdkn1a 8225
Dtx3l 8267
Litaf 8272
Ncf1 8310
Rrad 8339
Tnfrsf11a 8341
Slc7a7 8360
Prkch 8376
Clec12a 8399
Clec4a1 8411
Nfkbie 8416
Ikbke 8448
Parp14 8506
Slc11a1 8515
Socs1 8518



Here is the session info with all the versions of packages used.

sessionInfo()
## R version 4.0.2 (2020-06-22)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 18.04.4 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.7.1
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.7.1
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.1.0               GGally_2.0.0               
##  [3] beeswarm_0.2.3              gtools_3.8.2               
##  [5] echarts4r_0.3.2             mitch_1.0.6                
##  [7] MASS_7.3-51.6               fgsea_1.14.0               
##  [9] gplots_3.0.3                DESeq2_1.28.1              
## [11] SummarizedExperiment_1.18.1 DelayedArray_0.14.0        
## [13] matrixStats_0.56.0          Biobase_2.48.0             
## [15] GenomicRanges_1.40.0        GenomeInfoDb_1.24.2        
## [17] IRanges_2.22.2              S4Vectors_0.26.1           
## [19] BiocGenerics_0.34.0         reshape2_1.4.4             
## [21] forcats_0.5.0               stringr_1.4.0              
## [23] dplyr_1.0.0                 purrr_0.3.4                
## [25] readr_1.3.1                 tidyr_1.1.0                
## [27] tibble_3.0.1                ggplot2_3.3.2              
## [29] tidyverse_1.3.0            
## 
## loaded via a namespace (and not attached):
##  [1] colorspace_1.4-1       ellipsis_0.3.1         rprojroot_1.3-2       
##  [4] XVector_0.28.0         fs_1.4.2               rstudioapi_0.11       
##  [7] bit64_0.9-7            AnnotationDbi_1.50.1   fansi_0.4.1           
## [10] lubridate_1.7.9        xml2_1.3.2             splines_4.0.2         
## [13] geneplotter_1.66.0     knitr_1.29             jsonlite_1.7.0        
## [16] broom_0.5.6            annotate_1.66.0        dbplyr_1.4.4          
## [19] shiny_1.5.0            compiler_4.0.2         httr_1.4.1            
## [22] backports_1.1.8        assertthat_0.2.1       Matrix_1.2-18         
## [25] fastmap_1.0.1          cli_2.0.2              later_1.1.0.1         
## [28] htmltools_0.5.0        tools_4.0.2            gtable_0.3.0          
## [31] glue_1.4.1             GenomeInfoDbData_1.2.3 fastmatch_1.1-0       
## [34] Rcpp_1.0.4.6           cellranger_1.1.0       vctrs_0.3.1           
## [37] gdata_2.18.0           nlme_3.1-148           xfun_0.15             
## [40] testthat_2.3.2         rvest_0.3.5            mime_0.9              
## [43] lifecycle_0.2.0        XML_3.99-0.3           zlibbioc_1.34.0       
## [46] scales_1.1.1           hms_0.5.3              promises_1.1.1        
## [49] RColorBrewer_1.1-2     yaml_2.2.1             memoise_1.1.0         
## [52] gridExtra_2.3          reshape_0.8.8          stringi_1.4.6         
## [55] RSQLite_2.2.0          highr_0.8              genefilter_1.70.0     
## [58] desc_1.2.0             caTools_1.18.0         BiocParallel_1.22.0   
## [61] rlang_0.4.6            pkgconfig_2.0.3        bitops_1.0-6          
## [64] evaluate_0.14          lattice_0.20-41        htmlwidgets_1.5.1     
## [67] bit_1.1-15.2           tidyselect_1.1.0       plyr_1.8.6            
## [70] magrittr_1.5           R6_2.4.1               generics_0.0.2        
## [73] DBI_1.1.0              pillar_1.4.4           haven_2.3.1           
## [76] withr_2.2.0            survival_3.2-3         RCurl_1.98-1.2        
## [79] modelr_0.1.8           crayon_1.3.4           KernSmooth_2.23-17    
## [82] rmarkdown_2.3          locfit_1.5-9.4         grid_4.0.2            
## [85] readxl_1.3.1           data.table_1.12.8      blob_1.2.1            
## [88] reprex_0.3.0           digest_0.6.25          pbmcapply_1.5.0       
## [91] xtable_1.8-4           httpuv_1.5.4           munsell_0.5.0

END of report