Mitch Report
Antony Kaspi & Mark Ziemann
date generated: 2020-10-08
Background
Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch
Input profiles
Here is the first few lines of the input profile.
## diabetes mitoG
## A1CF -6.9932602 1.51849480
## A3GALT2 -0.4812996 0.04044782
## A4GALT 3.2528398 -0.66706468
## A4GNT 1.2215327 0.29060394
## AAAS 1.7926927 -0.52232889
## AACS -2.0466443 -0.59825125Here are some metrics about the input data profile:
| Profile metrics | |
|---|---|
| num_genes_in_profile | 15635 |
| duplicated_genes_present | 0 |
| num_profile_genes_in_sets | 2931 |
| num_profile_genes_not_in_sets | 12704 |
| profile_pearson_correl | -0.26909 |
| profile_spearman_correl | -0.21206 |
Here is a plot of the input profiles. Note the dynamic ranges. 
Here is the contour plot of the profile including all detected genes. 
Input genesets
Here are some metrics about the gene sets used: GMT file of genesets: genesetsofinterest.gmt
| Gene sets metrics | |
|---|---|
| num_genesets | 47 |
| num_genesets_excluded | 10 |
| num_genesets_included | 37 |
Gene sets by quadrant
Number of significant gene sets (FDR<0.05)= 18 
Interactive enrichment scatterplot
All sets with FDR<0.05. Try hovering over the points.
A heatmap of S values for top results
A plot of effect size versus significance
Significance is the -log2(p.adjustMANOVA) and effect size is the s.dist which is the hypotenuse of the s scores.
Results table
Top N= 37 gene sets
| set | setSize | pMANOVA | p.adjustMANOVA | s.dist | s.diabetes | s.mitoG | p.diabetes | p.mitoG |
|---|---|---|---|---|---|---|---|---|
| Gluconeogenesis | 30 | 4.13e-06 | 1.39e-05 | 0.4930 | 0.48200 | 0.1010 | 4.87e-06 | 3.37e-01 |
| GSE9006 TYPE 1 VS TYPE 2 DIABETES PBMC AT DX DN | 179 | 4.05e-19 | 7.48e-18 | 0.4310 | -0.21200 | 0.3750 | 1.04e-06 | 4.89e-18 |
| Activation of NF-kappaB in B cells | 66 | 8.09e-07 | 3.33e-06 | 0.4140 | -0.31900 | 0.2650 | 7.64e-06 | 2.02e-04 |
| GSE9006 HEALTHY VS TYPE 1 DIABETES PBMC 1MONTH POST DX UP | 192 | 1.16e-11 | 1.07e-10 | 0.3130 | -0.10600 | 0.2940 | 1.11e-02 | 2.31e-12 |
| GSE9006 HEALTHY VS TYPE 1 DIABETES PBMC AT DX UP | 186 | 8.32e-12 | 1.03e-10 | 0.3070 | -0.04840 | 0.3040 | 2.56e-01 | 9.83e-13 |
| BAELDE DIABETIC NEPHROPATHY DN | 418 | 8.12e-24 | 3.00e-22 | 0.2980 | -0.04700 | 0.2940 | 1.00e-01 | 7.25e-25 |
| HP MATERNAL DIABETES | 21 | 5.43e-02 | 9.13e-02 | 0.2910 | -0.03160 | -0.2890 | 8.02e-01 | 2.18e-02 |
| Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | 120 | 5.69e-08 | 3.51e-07 | 0.2740 | 0.23800 | 0.1370 | 6.91e-06 | 9.66e-03 |
| Respiratory electron transport | 99 | 2.09e-06 | 7.73e-06 | 0.2660 | 0.22100 | 0.1480 | 1.44e-04 | 1.12e-02 |
| GSE9006 HEALTHY VS TYPE 2 DIABETES PBMC AT DX DN | 170 | 4.30e-07 | 1.99e-06 | 0.2590 | -0.11900 | 0.2300 | 7.42e-03 | 2.38e-07 |
| KEGG TYPE I DIABETES MELLITUS | 25 | 6.90e-02 | 1.09e-01 | 0.2560 | -0.25500 | -0.0245 | 2.74e-02 | 8.32e-01 |
| HP TYPE I DIABETES MELLITUS | 38 | 1.16e-02 | 2.69e-02 | 0.2520 | 0.11700 | 0.2240 | 2.12e-01 | 1.70e-02 |
| The citric acid (TCA) cycle and respiratory electron transport | 168 | 1.10e-08 | 8.16e-08 | 0.2410 | 0.16200 | 0.1780 | 2.88e-04 | 7.32e-05 |
| HP NEONATAL INSULIN DEPENDENT DIABETES MELLITUS | 10 | 3.38e-01 | 4.47e-01 | 0.2390 | 0.16600 | 0.1720 | 3.64e-01 | 3.47e-01 |
| GSE9006 HEALTHY VS TYPE 1 DIABETES PBMC 4MONTH POST DX UP | 193 | 1.45e-07 | 7.66e-07 | 0.2310 | -0.00752 | 0.2310 | 8.57e-01 | 3.40e-08 |
| BAELDE DIABETIC NEPHROPATHY UP | 78 | 7.25e-04 | 2.24e-03 | 0.2260 | 0.20500 | 0.0948 | 1.75e-03 | 1.48e-01 |
| KEGG MATURITY ONSET DIABETES OF THE YOUNG | 13 | 4.35e-01 | 5.37e-01 | 0.2200 | 0.08870 | -0.2010 | 5.80e-01 | 2.09e-01 |
| GSE9006 TYPE 1 VS TYPE 2 DIABETES PBMC AT DX UP | 195 | 1.03e-03 | 2.94e-03 | 0.1580 | 0.03210 | -0.1540 | 4.40e-01 | 2.08e-04 |
| GSE40225 WT VS RIP B7X DIABETIC MOUSE PANCREATIC CD8 TCELL DN | 179 | 5.15e-03 | 1.27e-02 | 0.1530 | -0.08420 | 0.1280 | 5.25e-02 | 3.12e-03 |
| GSE9006 TYPE 1 DIABETES AT DX VS 4MONTH POST DX PBMC DN | 148 | 3.93e-03 | 1.04e-02 | 0.1410 | 0.08650 | 0.1120 | 6.96e-02 | 1.92e-02 |
| HP NEPHROPATHY | 90 | 4.60e-02 | 8.52e-02 | 0.1350 | 0.08870 | 0.1010 | 1.46e-01 | 9.74e-02 |
| GSE9006 TYPE 1 DIABETES AT DX VS 1MONTH POST DX PBMC UP | 187 | 1.50e-02 | 3.26e-02 | 0.1320 | -0.05630 | 0.1190 | 1.85e-01 | 5.11e-03 |
| GSE9006 HEALTHY VS TYPE 1 DIABETES PBMC AT DX DN | 162 | 1.69e-02 | 3.48e-02 | 0.1220 | 0.02510 | 0.1200 | 5.82e-01 | 8.75e-03 |
| WP TYPE II DIABETES MELLITUS | 20 | 6.20e-01 | 7.40e-01 | 0.1220 | -0.00833 | -0.1210 | 9.49e-01 | 3.47e-01 |
| HP TYPE II DIABETES MELLITUS | 139 | 7.92e-02 | 1.17e-01 | 0.1200 | 0.10400 | -0.0590 | 3.42e-02 | 2.31e-01 |
| GSE9006 1MONTH VS 4MONTH POST TYPE 1 DIABETES DX PBMC UP | 167 | 2.88e-02 | 5.61e-02 | 0.1170 | -0.00264 | 0.1170 | 9.53e-01 | 8.93e-03 |
| GSE9006 TYPE 1 DIABETES AT DX VS 4MONTH POST DX PBMC UP | 182 | 4.87e-02 | 8.58e-02 | 0.1050 | -0.00885 | 0.1050 | 8.37e-01 | 1.48e-02 |
| GSE40225 WT VS RIP B7X DIABETIC MOUSE PANCREATIC CD8 TCELL UP | 169 | 1.03e-01 | 1.46e-01 | 0.1040 | -0.08490 | 0.0603 | 5.73e-02 | 1.77e-01 |
| GSE9006 TYPE 1 DIABETES AT DX VS 1MONTH POST DX PBMC DN | 165 | 7.05e-02 | 1.09e-01 | 0.0925 | 0.05840 | 0.0718 | 1.96e-01 | 1.12e-01 |
| GSE9006 HEALTHY VS TYPE 1 DIABETES PBMC 1MONTH POST DX DN | 153 | 2.17e-01 | 2.97e-01 | 0.0896 | 0.05170 | -0.0732 | 2.71e-01 | 1.19e-01 |
| HP INSULIN RESISTANT DIABETES MELLITUS | 26 | 7.61e-01 | 8.04e-01 | 0.0749 | 0.04100 | 0.0627 | 7.17e-01 | 5.80e-01 |
| KEGG TYPE II DIABETES MELLITUS | 41 | 7.21e-01 | 7.85e-01 | 0.0692 | 0.01080 | 0.0684 | 9.05e-01 | 4.49e-01 |
| TNFR1-induced NFkappaB signaling pathway | 26 | 8.30e-01 | 8.30e-01 | 0.0633 | 0.02260 | 0.0591 | 8.42e-01 | 6.02e-01 |
| HP DIABETES INSIPIDUS | 33 | 8.20e-01 | 8.30e-01 | 0.0576 | 0.05290 | 0.0229 | 5.99e-01 | 8.20e-01 |
| GSE9006 HEALTHY VS TYPE 1 DIABETES PBMC 4MONTH POST DX DN | 160 | 4.25e-01 | 5.37e-01 | 0.0535 | -0.03110 | -0.0435 | 4.97e-01 | 3.43e-01 |
| GSE9006 HEALTHY VS TYPE 2 DIABETES PBMC AT DX UP | 189 | 6.48e-01 | 7.49e-01 | 0.0431 | 0.02540 | -0.0348 | 5.48e-01 | 4.10e-01 |
| GSE9006 1MONTH VS 4MONTH POST TYPE 1 DIABETES DX PBMC DN | 152 | 7.21e-01 | 7.85e-01 | 0.0350 | 0.03300 | 0.0114 | 4.83e-01 | 8.08e-01 |
Results (complete table)
Click HERE to show results for all gene sets
| set | setSize | pMANOVA | p.adjustMANOVA | s.dist | s.diabetes | s.mitoG | p.diabetes | p.mitoG |
|---|---|---|---|---|---|---|---|---|
| Gluconeogenesis | 30 | 4.13e-06 | 1.39e-05 | 0.4930 | 0.48200 | 0.1010 | 4.87e-06 | 3.37e-01 |
| GSE9006 TYPE 1 VS TYPE 2 DIABETES PBMC AT DX DN | 179 | 4.05e-19 | 7.48e-18 | 0.4310 | -0.21200 | 0.3750 | 1.04e-06 | 4.89e-18 |
| Activation of NF-kappaB in B cells | 66 | 8.09e-07 | 3.33e-06 | 0.4140 | -0.31900 | 0.2650 | 7.64e-06 | 2.02e-04 |
| GSE9006 HEALTHY VS TYPE 1 DIABETES PBMC 1MONTH POST DX UP | 192 | 1.16e-11 | 1.07e-10 | 0.3130 | -0.10600 | 0.2940 | 1.11e-02 | 2.31e-12 |
| GSE9006 HEALTHY VS TYPE 1 DIABETES PBMC AT DX UP | 186 | 8.32e-12 | 1.03e-10 | 0.3070 | -0.04840 | 0.3040 | 2.56e-01 | 9.83e-13 |
| BAELDE DIABETIC NEPHROPATHY DN | 418 | 8.12e-24 | 3.00e-22 | 0.2980 | -0.04700 | 0.2940 | 1.00e-01 | 7.25e-25 |
| HP MATERNAL DIABETES | 21 | 5.43e-02 | 9.13e-02 | 0.2910 | -0.03160 | -0.2890 | 8.02e-01 | 2.18e-02 |
| Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | 120 | 5.69e-08 | 3.51e-07 | 0.2740 | 0.23800 | 0.1370 | 6.91e-06 | 9.66e-03 |
| Respiratory electron transport | 99 | 2.09e-06 | 7.73e-06 | 0.2660 | 0.22100 | 0.1480 | 1.44e-04 | 1.12e-02 |
| GSE9006 HEALTHY VS TYPE 2 DIABETES PBMC AT DX DN | 170 | 4.30e-07 | 1.99e-06 | 0.2590 | -0.11900 | 0.2300 | 7.42e-03 | 2.38e-07 |
| KEGG TYPE I DIABETES MELLITUS | 25 | 6.90e-02 | 1.09e-01 | 0.2560 | -0.25500 | -0.0245 | 2.74e-02 | 8.32e-01 |
| HP TYPE I DIABETES MELLITUS | 38 | 1.16e-02 | 2.69e-02 | 0.2520 | 0.11700 | 0.2240 | 2.12e-01 | 1.70e-02 |
| The citric acid (TCA) cycle and respiratory electron transport | 168 | 1.10e-08 | 8.16e-08 | 0.2410 | 0.16200 | 0.1780 | 2.88e-04 | 7.32e-05 |
| HP NEONATAL INSULIN DEPENDENT DIABETES MELLITUS | 10 | 3.38e-01 | 4.47e-01 | 0.2390 | 0.16600 | 0.1720 | 3.64e-01 | 3.47e-01 |
| GSE9006 HEALTHY VS TYPE 1 DIABETES PBMC 4MONTH POST DX UP | 193 | 1.45e-07 | 7.66e-07 | 0.2310 | -0.00752 | 0.2310 | 8.57e-01 | 3.40e-08 |
| BAELDE DIABETIC NEPHROPATHY UP | 78 | 7.25e-04 | 2.24e-03 | 0.2260 | 0.20500 | 0.0948 | 1.75e-03 | 1.48e-01 |
| KEGG MATURITY ONSET DIABETES OF THE YOUNG | 13 | 4.35e-01 | 5.37e-01 | 0.2200 | 0.08870 | -0.2010 | 5.80e-01 | 2.09e-01 |
| GSE9006 TYPE 1 VS TYPE 2 DIABETES PBMC AT DX UP | 195 | 1.03e-03 | 2.94e-03 | 0.1580 | 0.03210 | -0.1540 | 4.40e-01 | 2.08e-04 |
| GSE40225 WT VS RIP B7X DIABETIC MOUSE PANCREATIC CD8 TCELL DN | 179 | 5.15e-03 | 1.27e-02 | 0.1530 | -0.08420 | 0.1280 | 5.25e-02 | 3.12e-03 |
| GSE9006 TYPE 1 DIABETES AT DX VS 4MONTH POST DX PBMC DN | 148 | 3.93e-03 | 1.04e-02 | 0.1410 | 0.08650 | 0.1120 | 6.96e-02 | 1.92e-02 |
| HP NEPHROPATHY | 90 | 4.60e-02 | 8.52e-02 | 0.1350 | 0.08870 | 0.1010 | 1.46e-01 | 9.74e-02 |
| GSE9006 TYPE 1 DIABETES AT DX VS 1MONTH POST DX PBMC UP | 187 | 1.50e-02 | 3.26e-02 | 0.1320 | -0.05630 | 0.1190 | 1.85e-01 | 5.11e-03 |
| GSE9006 HEALTHY VS TYPE 1 DIABETES PBMC AT DX DN | 162 | 1.69e-02 | 3.48e-02 | 0.1220 | 0.02510 | 0.1200 | 5.82e-01 | 8.75e-03 |
| WP TYPE II DIABETES MELLITUS | 20 | 6.20e-01 | 7.40e-01 | 0.1220 | -0.00833 | -0.1210 | 9.49e-01 | 3.47e-01 |
| HP TYPE II DIABETES MELLITUS | 139 | 7.92e-02 | 1.17e-01 | 0.1200 | 0.10400 | -0.0590 | 3.42e-02 | 2.31e-01 |
| GSE9006 1MONTH VS 4MONTH POST TYPE 1 DIABETES DX PBMC UP | 167 | 2.88e-02 | 5.61e-02 | 0.1170 | -0.00264 | 0.1170 | 9.53e-01 | 8.93e-03 |
| GSE9006 TYPE 1 DIABETES AT DX VS 4MONTH POST DX PBMC UP | 182 | 4.87e-02 | 8.58e-02 | 0.1050 | -0.00885 | 0.1050 | 8.37e-01 | 1.48e-02 |
| GSE40225 WT VS RIP B7X DIABETIC MOUSE PANCREATIC CD8 TCELL UP | 169 | 1.03e-01 | 1.46e-01 | 0.1040 | -0.08490 | 0.0603 | 5.73e-02 | 1.77e-01 |
| GSE9006 TYPE 1 DIABETES AT DX VS 1MONTH POST DX PBMC DN | 165 | 7.05e-02 | 1.09e-01 | 0.0925 | 0.05840 | 0.0718 | 1.96e-01 | 1.12e-01 |
| GSE9006 HEALTHY VS TYPE 1 DIABETES PBMC 1MONTH POST DX DN | 153 | 2.17e-01 | 2.97e-01 | 0.0896 | 0.05170 | -0.0732 | 2.71e-01 | 1.19e-01 |
| HP INSULIN RESISTANT DIABETES MELLITUS | 26 | 7.61e-01 | 8.04e-01 | 0.0749 | 0.04100 | 0.0627 | 7.17e-01 | 5.80e-01 |
| KEGG TYPE II DIABETES MELLITUS | 41 | 7.21e-01 | 7.85e-01 | 0.0692 | 0.01080 | 0.0684 | 9.05e-01 | 4.49e-01 |
| TNFR1-induced NFkappaB signaling pathway | 26 | 8.30e-01 | 8.30e-01 | 0.0633 | 0.02260 | 0.0591 | 8.42e-01 | 6.02e-01 |
| HP DIABETES INSIPIDUS | 33 | 8.20e-01 | 8.30e-01 | 0.0576 | 0.05290 | 0.0229 | 5.99e-01 | 8.20e-01 |
| GSE9006 HEALTHY VS TYPE 1 DIABETES PBMC 4MONTH POST DX DN | 160 | 4.25e-01 | 5.37e-01 | 0.0535 | -0.03110 | -0.0435 | 4.97e-01 | 3.43e-01 |
| GSE9006 HEALTHY VS TYPE 2 DIABETES PBMC AT DX UP | 189 | 6.48e-01 | 7.49e-01 | 0.0431 | 0.02540 | -0.0348 | 5.48e-01 | 4.10e-01 |
| GSE9006 1MONTH VS 4MONTH POST TYPE 1 DIABETES DX PBMC DN | 152 | 7.21e-01 | 7.85e-01 | 0.0350 | 0.03300 | 0.0114 | 4.83e-01 | 8.08e-01 |
Detailed Gene set reports
Gluconeogenesis
| metric | value |
|---|---|
| setSize | 30 |
| pMANOVA | 4.13e-06 |
| p.adjustMANOVA | 1.39e-05 |
| s.dist | 0.493 |
| s.diabetes | 0.482 |
| s.mitoG | 0.101 |
| p.diabetes | 4.87e-06 |
| p.mitoG | 0.337 |
| Gene | diabetes | mitoG |
|---|---|---|
| ENO1 | 8244.0 | 7737.0 |
| ALDOB | 6728.0 | 7388.0 |
| GOT1 | 7006.0 | 7048.0 |
| PGAM2 | 7034.0 | 6971.0 |
| PCK1 | 6911.0 | 5688.0 |
| SLC25A12 | 7967.0 | 4933.0 |
| GOT2 | 7334.0 | 4691.0 |
| GPI | 4816.0 | 5422.0 |
| ALDOA | 6979.5 | 3652.5 |
| FBP1 | 7186.0 | 2802.0 |
| MDH1 | 4402.0 | 4491.0 |
| MDH2 | 3713.0 | 4456.0 |
| FBP2 | 8143.0 | 1918.0 |
| SLC37A4 | 5992.0 | 2463.0 |
| PGAM1 | 1992.0 | 4530.0 |
| SLC25A13 | 3242.0 | 999.0 |
| SLC25A1 | 3746.0 | 544.0 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| ALDOA | 6979.5 | 3652.5 |
| ALDOB | 6728.0 | 7388.0 |
| ALDOC | 8058.0 | -926.0 |
| ENO1 | 8244.0 | 7737.0 |
| ENO2 | 3279.0 | -2394.0 |
| ENO3 | 2281.0 | -3777.0 |
| FBP1 | 7186.0 | 2802.0 |
| FBP2 | 8143.0 | 1918.0 |
| G6PC | -4387.0 | 3036.0 |
| G6PC3 | -77.0 | -5754.0 |
| GAPDHS | -249.0 | -6258.0 |
| GOT1 | 7006.0 | 7048.0 |
| GOT2 | 7334.0 | 4691.0 |
| GPI | 4816.0 | 5422.0 |
| MDH1 | 4402.0 | 4491.0 |
| MDH2 | 3713.0 | 4456.0 |
| PC | -4135.0 | -1520.0 |
| PCK1 | 6911.0 | 5688.0 |
| PCK2 | 7209.0 | -2828.0 |
| PGAM1 | 1992.0 | 4530.0 |
| PGAM2 | 7034.0 | 6971.0 |
| PGK1 | -656.0 | 7226.0 |
| SLC25A1 | 3746.0 | 544.0 |
| SLC25A10 | 6761.5 | -5719.5 |
| SLC25A11 | 5582.0 | -2414.0 |
| SLC25A12 | 7967.0 | 4933.0 |
| SLC25A13 | 3242.0 | 999.0 |
| SLC37A1 | 6725.0 | -4214.0 |
| SLC37A2 | -5241.0 | 4444.0 |
| SLC37A4 | 5992.0 | 2463.0 |
GSE9006_TYPE_1_VS_TYPE_2_DIABETES_PBMC_AT_DX_DN
| metric | value |
|---|---|
| setSize | 179 |
| pMANOVA | 4.05e-19 |
| p.adjustMANOVA | 7.48e-18 |
| s.dist | 0.431 |
| s.diabetes | -0.212 |
| s.mitoG | 0.375 |
| p.diabetes | 1.04e-06 |
| p.mitoG | 4.89e-18 |
| Gene | diabetes | mitoG |
|---|---|---|
| HSPA4L | -7193 | 8500 |
| CLOCK | -7043 | 8412 |
| SAV1 | -7082 | 8274 |
| PSMD1 | -6497 | 8619 |
| CHD9 | -6925 | 8050 |
| UGP2 | -6121 | 8636 |
| PSMA1 | -6705 | 7838 |
| GTF2H1 | -6106 | 8498 |
| RPS6KA3 | -6111 | 8270 |
| MFAP3L | -7327 | 6664 |
| GDI2 | -5894 | 8074 |
| DPP8 | -5963 | 7906 |
| VPS35 | -5441 | 8535 |
| PHF20L1 | -5809 | 7968 |
| RNFT1 | -7085 | 6460 |
| TRIM44 | -6012 | 7523 |
| SELENOP | -7347 | 6139 |
| RC3H2 | -5550 | 7956 |
| USP9X | -5668 | 7709 |
| DNM1L | -4825 | 8774 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| ABCC3 | 8151.0 | 1041.0 |
| ACSL5 | 6398.0 | 6307.0 |
| ADGRE1 | -6270.0 | 6567.0 |
| ADIPOR2 | -4637.0 | 5912.0 |
| ADK | -3517.0 | 5789.0 |
| AFTPH | -5292.0 | 7576.0 |
| AHCYL1 | -5585.0 | 5114.0 |
| ANXA2 | -337.0 | 8406.0 |
| ANXA4 | 6843.0 | 3481.0 |
| AP3B1 | 3159.0 | 1998.0 |
| ARHGAP15 | -1750.0 | 6480.0 |
| ARHGEF12 | -6487.0 | 5930.0 |
| ARL6IP5 | -696.0 | 6533.0 |
| ARPC2 | -4512.0 | 8767.0 |
| ASAP1 | -4994.0 | 4607.0 |
| ASAP2 | -833.0 | 6296.0 |
| ASH1L | 2351.0 | 7274.0 |
| ATP2B4 | 7691.0 | 7255.0 |
| ATP5F1C | 164.0 | 8242.0 |
| ATP6V1E1 | -704.0 | 8548.0 |
| BPTF | -4758.0 | 6405.0 |
| C11orf49 | 4238.0 | -2413.0 |
| C21orf91 | -4198.0 | 8254.0 |
| CASP1 | -1051.0 | 1558.0 |
| CCNI | 265.0 | 6150.0 |
| CD53 | -3501.0 | 7525.0 |
| CDC40 | 1666.0 | 5218.0 |
| CEMIP | 6626.0 | 1672.0 |
| CHD9 | -6925.0 | 8050.0 |
| CLDN6 | -3611.0 | -2444.0 |
| CLEC4A | 580.0 | -5426.0 |
| CLOCK | -7043.0 | 8412.0 |
| CLTC | -4493.0 | 8248.0 |
| CNOT1 | -2585.0 | 3418.0 |
| COMMD10 | 4464.0 | 3207.0 |
| COPA | 488.0 | 2943.0 |
| CPQ | -7071.0 | -13.0 |
| CRK | -3124.0 | 6926.0 |
| DAB2 | -5689.0 | 1606.0 |
| DENND1B | -3640.0 | 6236.0 |
| DENND4C | -5667.0 | 856.0 |
| DHTKD1 | 4800.0 | -3721.0 |
| DHX32 | -759.0 | 5873.0 |
| DNM1L | -4825.0 | 8774.0 |
| DPP8 | -5963.0 | 7906.0 |
| EIF2S2 | -3307.0 | 8799.0 |
| EMSY | -4472.0 | 2078.0 |
| EPS8 | -6974.0 | 4802.0 |
| ESD | 771.0 | 8516.0 |
| EXPH5 | 1020.0 | 7614.0 |
| F13A1 | 3019.0 | 4962.0 |
| FAM114A1 | 3334.0 | 8336.0 |
| FBXO11 | -2703.0 | 8171.0 |
| FBXO9 | -3297.0 | -3812.0 |
| FOXC1 | 5241.0 | -2301.0 |
| GABARAPL2 | -1204.0 | 2829.0 |
| GART | -5631.0 | -3257.0 |
| GCNT1 | -6421.0 | -331.0 |
| GDAP2 | 1325.0 | 7455.0 |
| GDI2 | -5894.0 | 8074.0 |
| GFOD2 | 714.0 | -3471.0 |
| GGPS1 | -2197.0 | 7394.0 |
| GMFG | 3969.0 | 7186.0 |
| GNL3L | -498.0 | 5906.0 |
| GNPAT | -6628.0 | -27.0 |
| GSTO1 | 8023.0 | 4922.0 |
| GTF2H1 | -6106.0 | 8498.0 |
| GUCY1A1 | 1918.0 | 7519.0 |
| GUCY1B1 | -1671.0 | 7666.0 |
| HSPA4L | -7193.0 | 8500.0 |
| ITGB5 | 7359.0 | 1316.0 |
| ITPR2 | 4185.0 | -2206.0 |
| KCTD20 | 402.0 | 2843.0 |
| KIAA0586 | -3159.0 | -2100.0 |
| KLF6 | 145.0 | 7678.0 |
| KLF7 | -4593.0 | 8044.0 |
| KPNA3 | -1498.0 | 8389.0 |
| L1TD1 | 437.0 | -161.0 |
| LAMTOR5 | 4258.0 | 4393.0 |
| LEPROT | 7343.0 | -34.0 |
| LGALS8 | 4547.0 | 6252.0 |
| LHFPL6 | -492.0 | 8054.0 |
| LMBRD1 | 4227.0 | 4468.0 |
| LPP | 7785.0 | 3122.0 |
| MCTP1 | -5061.0 | 4365.0 |
| MDH1 | 4402.0 | 4491.0 |
| METTL9 | -553.0 | 7370.0 |
| MFAP3L | -7327.0 | 6664.0 |
| MGST3 | 8217.0 | 479.0 |
| MICU1 | -552.0 | 6566.0 |
| MINDY2 | -6596.0 | 2386.0 |
| MMRN1 | 202.0 | 7918.0 |
| MPHOSPH6 | -3203.0 | 7923.0 |
| MR1 | 6506.0 | 5559.0 |
| MRPS22 | -6062.0 | 5844.0 |
| MSH3 | 1132.0 | -2806.0 |
| MTF1 | -4371.0 | -3922.0 |
| NCOA1 | -3434.0 | 7005.0 |
| NIT2 | -5666.0 | -1701.0 |
| NOVA1 | -2740.0 | -4008.0 |
| OSBPL1A | 6468.0 | 6678.0 |
| OXA1L | 4609.0 | -4940.0 |
| PAPSS2 | 7044.0 | -2227.0 |
| PARP8 | -7014.0 | -116.0 |
| PCNX1 | 7739.0 | 781.0 |
| PDE8A | -3329.0 | 7592.0 |
| PDXK | 8266.0 | -2949.0 |
| PHF20L1 | -5809.0 | 7968.0 |
| PIAS1 | 3194.0 | 2440.0 |
| POGLUT1 | -1880.0 | 2758.0 |
| PRKAG1 | 1680.0 | -288.0 |
| PRKCB | -5598.0 | 5660.0 |
| PSMA1 | -6705.0 | 7838.0 |
| PSMA7 | 1612.0 | 7052.0 |
| PSMC1 | -1312.0 | 4327.0 |
| PSMC2 | -6765.0 | 4648.0 |
| PSMD1 | -6497.0 | 8619.0 |
| PTER | -4312.0 | 3141.0 |
| PURA | -6554.0 | -808.0 |
| PUS3 | -4535.0 | 6560.0 |
| RAB11FIP2 | 4139.0 | 931.0 |
| RAB3GAP2 | 1771.0 | -2399.0 |
| RAD17 | -430.0 | 6957.0 |
| RBBP6 | 3444.0 | 5157.0 |
| RBMS1 | -4349.0 | 7009.0 |
| RBPJ | 2571.0 | 4528.0 |
| RC3H2 | -5550.0 | 7956.0 |
| REL | -2309.0 | 7411.0 |
| RHEB | -3280.0 | -1691.0 |
| RNF41 | 474.0 | 2919.0 |
| RNFT1 | -7085.0 | 6460.0 |
| ROCK2 | -1368.0 | 8738.0 |
| RPL12 | 6107.0 | -5604.0 |
| RPS6KA3 | -6111.0 | 8270.0 |
| RPS6KA5 | 2516.0 | -3206.0 |
| RTCB | -1912.0 | -1661.0 |
| RUFY2 | 6866.0 | 4915.0 |
| SAP18 | -2023.0 | 7183.0 |
| SAV1 | -7082.0 | 8274.0 |
| SCAF4 | -1040.0 | -4854.0 |
| SCAMP1 | 7264.0 | 2855.0 |
| SELENOP | -7347.0 | 6139.0 |
| SELP | 5864.0 | 2861.0 |
| SERF2 | -2395.0 | -2526.0 |
| SLC17A5 | 2333.0 | 243.0 |
| SMAD1 | 5880.0 | 5459.0 |
| SON | -1196.0 | 3884.0 |
| SPARC | 6297.0 | 8700.0 |
| SPATS2L | -7291.0 | 4666.0 |
| SRGAP2 | -1169.0 | -688.0 |
| STAT3 | 8126.0 | 4982.0 |
| STRADA | 5090.0 | -5448.0 |
| STRN | -4029.0 | 6779.0 |
| STX18 | -6160.0 | 5652.0 |
| STXBP5L | -7008.0 | -3600.0 |
| SYT11 | 727.0 | 3892.0 |
| TANK | -4899.0 | 6416.0 |
| TAX1BP1 | 3157.0 | 7948.0 |
| TBC1D19 | -6018.0 | 3271.0 |
| TBC1D5 | 519.0 | -4097.0 |
| TIA1 | -1179.0 | -3112.0 |
| TMEM50A | -5438.0 | 6054.0 |
| TMF1 | -1973.0 | 8658.0 |
| TNFSF10 | -6011.0 | 987.0 |
| TOM1L1 | -2990.0 | 3660.0 |
| TPTE | -5920.5 | 6543.5 |
| TRIM44 | -6012.0 | 7523.0 |
| TRPC4 | -3076.0 | -324.0 |
| TUBD1 | -1572.0 | -5130.0 |
| UBE2L3 | -4226.5 | 5465.5 |
| UGP2 | -6121.0 | 8636.0 |
| USP9X | -5668.0 | 7709.0 |
| UVRAG | -5823.0 | -64.0 |
| VCL | -4796.0 | 7947.0 |
| VPS35 | -5441.0 | 8535.0 |
| XAF1 | -6155.0 | 1910.0 |
| XK | -1266.0 | 5749.0 |
| YIPF6 | -4393.0 | 6442.0 |
| ZNF318 | -4818.0 | -682.0 |
Activation of NF-kappaB in B cells
| metric | value |
|---|---|
| setSize | 66 |
| pMANOVA | 8.09e-07 |
| p.adjustMANOVA | 3.33e-06 |
| s.dist | 0.414 |
| s.diabetes | -0.319 |
| s.mitoG | 0.265 |
| p.diabetes | 7.64e-06 |
| p.mitoG | 0.000202 |
| Gene | diabetes | mitoG |
|---|---|---|
| PSMC6 | -6851.0 | 8666.0 |
| UBB | -7104.0 | 8341.0 |
| PSME4 | -6830.0 | 8511.0 |
| SKP1 | -6803.0 | 8394.0 |
| PSMD1 | -6497.0 | 8619.0 |
| PSMD12 | -6149.0 | 8628.0 |
| PSMD7 | -6943.0 | 7625.0 |
| PSMA1 | -6705.0 | 7838.0 |
| UBC | -6013.0 | 8514.0 |
| PSMC4 | -6423.0 | 7920.0 |
| PSMD14 | -6080.0 | 8262.0 |
| PSMD5 | -6156.0 | 7150.0 |
| PSMD6 | -6385.0 | 6157.0 |
| PSMD11 | -6873.0 | 5201.0 |
| PSMA2 | -5464.5 | 6058.5 |
| PRKCB | -5598.0 | 5660.0 |
| CHUK | -3701.0 | 8556.0 |
| PSMC2 | -6765.0 | 4648.0 |
| PSMB1 | -5281.0 | 5936.0 |
| PSMA5 | -6660.0 | 4497.0 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| BCL10 | -3598.0 | 5942.0 |
| BTRC | 3218.0 | -5334.0 |
| CARD11 | -3020.0 | 3028.0 |
| CHUK | -3701.0 | 8556.0 |
| CUL1 | -2997.0 | 6875.0 |
| FBXW11 | -3788.0 | 3125.0 |
| IKBKB | -1785.0 | -5829.0 |
| IKBKG | 3700.0 | -677.0 |
| MALT1 | -2981.0 | 1806.0 |
| MAP3K7 | 1594.0 | 7480.0 |
| NFKB1 | 5449.0 | 4035.0 |
| NFKBIA | 1631.0 | 4830.0 |
| NFKBIB | 3850.0 | 467.0 |
| NFKBIE | -4334.0 | -123.0 |
| PRKCB | -5598.0 | 5660.0 |
| PSMA1 | -6705.0 | 7838.0 |
| PSMA2 | -5464.5 | 6058.5 |
| PSMA3 | -3145.0 | 7801.0 |
| PSMA4 | -6074.0 | 4688.0 |
| PSMA5 | -6660.0 | 4497.0 |
| PSMA6 | -1954.0 | 8445.0 |
| PSMA7 | 1612.0 | 7052.0 |
| PSMA8 | 649.0 | -4004.0 |
| PSMB1 | -5281.0 | 5936.0 |
| PSMB10 | 3752.0 | -908.0 |
| PSMB11 | 1977.0 | -5501.0 |
| PSMB2 | 1472.0 | -4144.0 |
| PSMB3 | -3388.0 | 5539.0 |
| PSMB4 | -4941.0 | -5852.0 |
| PSMB5 | -1638.0 | -2409.0 |
| PSMB6 | 1806.0 | -1845.0 |
| PSMB7 | -4628.0 | -657.0 |
| PSMB8 | 1080.0 | -3793.0 |
| PSMB9 | 5987.0 | -4708.0 |
| PSMC1 | -1312.0 | 4327.0 |
| PSMC2 | -6765.0 | 4648.0 |
| PSMC3 | -4285.0 | 3386.0 |
| PSMC4 | -6423.0 | 7920.0 |
| PSMC5 | -4831.0 | 1120.0 |
| PSMC6 | -6851.0 | 8666.0 |
| PSMD1 | -6497.0 | 8619.0 |
| PSMD10 | -1613.0 | 2576.0 |
| PSMD11 | -6873.0 | 5201.0 |
| PSMD12 | -6149.0 | 8628.0 |
| PSMD13 | 1898.0 | 5044.0 |
| PSMD14 | -6080.0 | 8262.0 |
| PSMD2 | -6702.0 | -3836.0 |
| PSMD3 | -2532.0 | -3242.0 |
| PSMD4 | -5648.0 | 4994.0 |
| PSMD5 | -6156.0 | 7150.0 |
| PSMD6 | -6385.0 | 6157.0 |
| PSMD7 | -6943.0 | 7625.0 |
| PSMD8 | 1978.0 | 7546.0 |
| PSMD9 | 7707.5 | -894.5 |
| PSME1 | 2907.0 | 5905.0 |
| PSME2 | 1270.0 | -4595.0 |
| PSME3 | 752.0 | 7366.0 |
| PSME4 | -6830.0 | 8511.0 |
| PSMF1 | 5087.0 | 4771.0 |
| REL | -2309.0 | 7411.0 |
| RELA | 2579.0 | -2368.0 |
| RPS27A | -133.0 | -1807.0 |
| SKP1 | -6803.0 | 8394.0 |
| UBA52 | 7488.0 | -4269.0 |
| UBB | -7104.0 | 8341.0 |
| UBC | -6013.0 | 8514.0 |
GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_1MONTH_POST_DX_UP
| metric | value |
|---|---|
| setSize | 192 |
| pMANOVA | 1.16e-11 |
| p.adjustMANOVA | 1.07e-10 |
| s.dist | 0.313 |
| s.diabetes | -0.106 |
| s.mitoG | 0.294 |
| p.diabetes | 0.0111 |
| p.mitoG | 2.31e-12 |
| Gene | diabetes | mitoG |
|---|---|---|
| HNRNPA3 | -6985 | 8827 |
| HSP90B1 | -7279 | 8368 |
| CANX | -6936 | 8532 |
| PDIA3 | -7283 | 7821 |
| TRAM1 | -7037 | 8086 |
| SUMO3 | -7259 | 7825 |
| PDIA4 | -7329 | 7729 |
| HSPA5 | -7309 | 7589 |
| PCNP | -6253 | 8734 |
| RPN1 | -7121 | 7464 |
| ADAM10 | -6444 | 8149 |
| RNF11 | -7128 | 7320 |
| LYPLA1 | -6790 | 7638 |
| QKI | -6268 | 8165 |
| YWHAZ | -5614 | 8512 |
| GDI2 | -5894 | 8074 |
| EPRS1 | -5855 | 8062 |
| GALNT1 | -6827 | 6806 |
| BCAP31 | -6657 | 6845 |
| BTBD1 | -5007 | 8727 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| AAMP | 69.0 | -4287.0 |
| AATF | 2607.0 | 2827.0 |
| ACO2 | 7295.0 | 7282.0 |
| ACTG1 | -1502.0 | 1482.0 |
| ACTR2 | -5189.0 | 7356.0 |
| ADAM10 | -6444.0 | 8149.0 |
| ADNP2 | 2146.0 | 595.0 |
| AGPS | -7336.0 | 594.0 |
| AHCY | -3362.0 | -6342.0 |
| ALDOA | 6979.5 | 3652.5 |
| ANP32A | 3020.5 | 6935.5 |
| ANXA5 | 350.0 | 5743.0 |
| ARL6IP1 | -6592.5 | -1456.5 |
| ARPC4 | 3077.0 | 1525.0 |
| ATMIN | 3967.0 | -1041.0 |
| ATP5F1B | 1691.0 | 1750.0 |
| AZIN1 | 6036.0 | 4792.0 |
| BAG1 | 2254.0 | 6318.0 |
| BCAP31 | -6657.0 | 6845.0 |
| BMPR2 | 512.0 | 7927.0 |
| BNIP2 | 3400.0 | 6267.0 |
| BTBD1 | -5007.0 | 8727.0 |
| C8orf33 | 5060.0 | -3701.0 |
| CANX | -6936.0 | 8532.0 |
| CD69 | -4208.0 | 443.0 |
| CHEK2 | 2232.0 | 922.0 |
| CLN8 | -367.0 | -5559.0 |
| CLP1 | 4455.0 | -5275.0 |
| COPA | 488.0 | 2943.0 |
| COPS7B | -2394.0 | -5916.0 |
| CORO1C | -6048.0 | 6789.0 |
| CPNE3 | 1709.0 | 7633.0 |
| CPSF6 | -4618.0 | 2233.0 |
| CSDE1 | -3677.0 | 8769.0 |
| CSNK1G3 | -5311.0 | 8143.0 |
| CYBB | -5520.0 | 5307.0 |
| DAZAP2 | 5976.0 | 2413.0 |
| DDIT4 | 5684.0 | 4879.0 |
| DDX3X | 3775.0 | 8058.0 |
| DDX49 | 4404.0 | -1145.0 |
| DNAJA2 | -3327.0 | 8515.0 |
| DNAJB14 | 607.0 | 3352.0 |
| DPYSL2 | 1058.0 | 7621.0 |
| DR1 | 1246.0 | 8550.0 |
| DUSP10 | 4557.0 | 5745.0 |
| DUSP5 | 4923.0 | 4971.0 |
| ECSIT | -3596.0 | 1408.0 |
| EIF3I | 5694.0 | 2343.0 |
| EIF4G3 | -7083.0 | 1872.0 |
| ENSA | -1714.0 | 2979.0 |
| EPRS1 | -5855.0 | 8062.0 |
| EZR | 5644.0 | 6288.0 |
| FAM13A | 7985.0 | 1055.0 |
| FARSA | -2969.0 | -5485.0 |
| FLI1 | -110.0 | 7996.0 |
| FOXK2 | -5706.0 | 1999.0 |
| G3BP2 | -4462.0 | 5928.0 |
| GALNT1 | -6827.0 | 6806.0 |
| GALNT12 | 6172.0 | -2979.0 |
| GDI2 | -5894.0 | 8074.0 |
| GLUD1 | 8064.5 | 3730.5 |
| GLUD2 | 8064.5 | 3730.5 |
| GPAA1 | 696.0 | -5319.0 |
| GPI | 4816.0 | 5422.0 |
| GSR | -2480.0 | 4329.0 |
| HADHA | 6883.0 | 5617.0 |
| HIF1A | 7374.0 | 8562.0 |
| HMGB1 | 2876.0 | 8283.0 |
| HNRNPA1 | 7891.0 | -6290.0 |
| HNRNPA3 | -6985.0 | 8827.0 |
| HNRNPD | 6599.0 | 1068.0 |
| HNRNPH2 | -5391.0 | 5932.0 |
| HNRNPM | -6548.0 | -2929.0 |
| HNRNPR | -3972.0 | 1045.0 |
| HNRNPU | -5219.0 | 7082.0 |
| HSP90B1 | -7279.0 | 8368.0 |
| HSPA5 | -7309.0 | 7589.0 |
| HSPA9 | -566.0 | 8181.0 |
| IDS | -4361.5 | 6034.5 |
| IER5 | 5330.0 | 2127.0 |
| ILVBL | 3004.0 | -6442.0 |
| INPP5D | -1230.0 | 5535.0 |
| ITGB3 | 1530.5 | 4298.5 |
| JUN | 581.0 | 5314.0 |
| JUNB | 4544.0 | 2430.0 |
| KCTD3 | 6817.0 | -4081.0 |
| KDELR2 | -4969.0 | 8520.0 |
| KLF10 | 3691.0 | 2691.0 |
| KPNB1 | -1668.0 | 5829.0 |
| LAPTM5 | -5721.0 | 4643.0 |
| LRIG2 | -4032.0 | 2077.0 |
| LSM12 | -2869.0 | 4929.0 |
| LSM14A | -4311.0 | 7661.0 |
| LYPLA1 | -6790.0 | 7638.0 |
| MAP2K1 | 7852.0 | 3274.0 |
| MAPK1IP1L | 345.0 | -2618.0 |
| MAPRE1 | -3633.0 | 8509.0 |
| MATR3 | 5268.0 | -4256.0 |
| MBD2 | -1599.0 | 7442.0 |
| MDM4 | -2223.0 | -5305.0 |
| MKRN1 | -6560.0 | 3886.0 |
| MRPL12 | -2913.0 | 4144.0 |
| MRPS10 | 4929.0 | 5018.0 |
| MSN | -1294.0 | 5246.0 |
| MTHFD1 | 7003.0 | 2637.0 |
| NADSYN1 | 6875.0 | -6478.0 |
| NAPG | 3323.0 | 2180.0 |
| NCBP3 | 274.0 | 1327.0 |
| NDUFV1 | 4313.0 | -2431.0 |
| NKAPD1 | -880.0 | 7075.0 |
| NNT | 4576.0 | 4716.0 |
| NPTN | 2459.0 | 6839.0 |
| NRAS | 3837.0 | 7903.0 |
| ODF2 | 8196.0 | -5679.0 |
| ORAI2 | 4113.0 | 4514.0 |
| OSTF1 | 6553.0 | 5854.0 |
| PABPC4 | 2846.0 | -3784.0 |
| PAK2 | -4906.0 | 6708.0 |
| PCBP2 | 6135.0 | 1313.0 |
| PCNP | -6253.0 | 8734.0 |
| PDIA3 | -7283.0 | 7821.0 |
| PDIA4 | -7329.0 | 7729.0 |
| PDZK1IP1 | -3583.0 | -2856.0 |
| PIK3R1 | -839.0 | 8363.0 |
| PKN1 | 4322.0 | -4516.0 |
| PPP1CB | -4617.0 | 8661.0 |
| PPP3CB | -1150.0 | 4729.0 |
| PRIM2 | -1544.0 | -1595.0 |
| PRKAA1 | -4310.0 | 7164.0 |
| PRKDC | -5092.0 | 3381.0 |
| PSMC3 | -4285.0 | 3386.0 |
| PSMD2 | -6702.0 | -3836.0 |
| PSPN | -1715.0 | -1537.0 |
| PTBP3 | 5856.0 | 7175.0 |
| PTP4A2 | 3118.0 | 8121.0 |
| QKI | -6268.0 | 8165.0 |
| RAB40B | 4958.0 | -829.0 |
| RBBP4 | -6148.0 | 5835.0 |
| RBM3 | 8175.0 | 5192.0 |
| RBM39 | -4400.0 | 4908.0 |
| RNF11 | -7128.0 | 7320.0 |
| RNF38 | 2503.0 | -1772.0 |
| RNPS1 | 5559.0 | 6960.0 |
| RPN1 | -7121.0 | 7464.0 |
| RTN3 | -2760.0 | 5623.0 |
| SAFB | -1933.0 | -1132.0 |
| SAFB2 | 3321.0 | -6673.0 |
| SART1 | 2632.0 | -1920.0 |
| SEC31A | 835.0 | -552.0 |
| SFN | 3916.0 | 5704.0 |
| SFPQ | -5196.0 | -4828.0 |
| SIDT1 | -2430.0 | -1174.0 |
| SIK1 | 3616.5 | 666.5 |
| SLC35A2 | 2888.0 | -5791.0 |
| SLC35A3 | -2157.0 | 4799.0 |
| SLC39A7 | -6230.0 | 880.0 |
| SMARCA2 | -7342.0 | 1064.0 |
| SNTB2 | 5614.0 | 2572.0 |
| SNX6 | -7210.0 | 1661.0 |
| SOX4 | -2131.0 | 5537.0 |
| SPCS3 | 4330.0 | 1501.0 |
| SRRT | -6373.0 | -1448.0 |
| SRSF9 | -2009.0 | -5029.0 |
| STAU1 | -3137.0 | 6966.0 |
| STK17B | -265.0 | 7680.0 |
| STT3A | -6845.0 | 4709.0 |
| STX8 | 475.0 | 5557.0 |
| SUMO3 | -7259.0 | 7825.0 |
| SYNE2 | -5553.0 | 2300.0 |
| TAP2 | 5211.5 | -5555.5 |
| TENT5C | -779.0 | 7537.0 |
| TMED2 | -2351.0 | 6953.0 |
| TMEM248 | -5533.0 | 5899.0 |
| TMEM9B | -4417.0 | 4027.0 |
| TMOD3 | 576.0 | 8475.0 |
| TOB1 | 1023.0 | 6857.0 |
| TOMM22 | -4533.0 | 5264.0 |
| TPST2 | 5077.0 | -171.0 |
| TRAM1 | -7037.0 | 8086.0 |
| TRIM16 | 618.5 | 8118.5 |
| TXNIP | 2986.0 | 4021.0 |
| UGCG | -6237.0 | 4297.0 |
| UQCRC1 | 5627.0 | 1729.0 |
| URI1 | 5037.0 | 3911.0 |
| WDR18 | -5000.0 | -3150.0 |
| WTAP | -3354.0 | 6889.0 |
| XAB2 | 2873.0 | 3916.0 |
| XRCC6 | -1971.0 | 4034.0 |
| YBX3 | 5916.0 | 4090.0 |
| YWHAZ | -5614.0 | 8512.0 |
| ZNF394 | 73.0 | -278.0 |
| ZNF551 | -3852.0 | 2620.0 |
GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_AT_DX_UP
| metric | value |
|---|---|
| setSize | 186 |
| pMANOVA | 8.32e-12 |
| p.adjustMANOVA | 1.03e-10 |
| s.dist | 0.307 |
| s.diabetes | -0.0484 |
| s.mitoG | 0.304 |
| p.diabetes | 0.256 |
| p.mitoG | 9.83e-13 |
| Gene | diabetes | mitoG |
|---|---|---|
| SUMO3 | -7259 | 7825 |
| TENT5A | -6948 | 8031 |
| SERP1 | -6709 | 8229 |
| UGP2 | -6121 | 8636 |
| PSMA1 | -6705 | 7838 |
| MFAP3L | -7327 | 6664 |
| ABCB7 | -5950 | 8196 |
| MYLK | -7270 | 6685 |
| ATF4 | -6143 | 7857 |
| GDI2 | -5894 | 8074 |
| DPP8 | -5963 | 7906 |
| COPS2 | -5385 | 8716 |
| UCHL3 | -5410 | 8491 |
| RFTN1 | -5652 | 7575 |
| GMPS | -5160 | 8238 |
| DNM1L | -4825 | 8774 |
| EIF3E | -4677 | 8580 |
| VCL | -4796 | 7947 |
| SERINC3 | -4809 | 7490 |
| NCOA2 | -5757 | 5994 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| ABCB7 | -5950.0 | 8196.0 |
| AHCYL1 | -5585.0 | 5114.0 |
| ALDH6A1 | -2335.0 | 6484.0 |
| ALOX12 | 3935.0 | -912.0 |
| ANXA4 | 6843.0 | 3481.0 |
| AP1S2 | -2308.0 | 7787.0 |
| ARHGAP6 | -2621.0 | 1377.0 |
| ARHGEF10L | -7201.0 | -5313.0 |
| ARL6IP5 | -696.0 | 6533.0 |
| ASAP2 | -833.0 | 6296.0 |
| ASL | 7699.5 | -4876.5 |
| ASXL2 | 2377.0 | 3074.0 |
| ATF4 | -6143.0 | 7857.0 |
| ATMIN | 3967.0 | -1041.0 |
| ATP5F1C | 164.0 | 8242.0 |
| ATP5MG | 5923.5 | 564.5 |
| ATP5PO | 6640.5 | 7456.5 |
| AUTS2 | 6138.0 | -5187.0 |
| BIN2 | -3519.0 | 1037.0 |
| BTF3 | -2304.0 | 8350.0 |
| C1orf54 | 498.0 | -619.0 |
| C3 | 7675.0 | 3404.0 |
| CAST | 3920.0 | 8492.0 |
| CELF2 | -3363.0 | 6532.0 |
| CFLAR | -4054.0 | 2224.0 |
| CLNS1A | -2264.0 | 5698.0 |
| CLPB | 341.0 | -4352.0 |
| CLU | 7398.0 | 5822.0 |
| CMC4 | -6293.0 | 4956.0 |
| CNOT7 | -4683.0 | 3410.0 |
| COLQ | 5431.0 | -3281.0 |
| COPA | 488.0 | 2943.0 |
| COPS2 | -5385.0 | 8716.0 |
| COX7A2 | 7439.0 | -1673.0 |
| CPNE3 | 1709.0 | 7633.0 |
| CRYL1 | 7236.0 | 1237.0 |
| CTSK | -3257.0 | 7753.0 |
| CTTN | 211.0 | 2434.0 |
| DAB2 | -5689.0 | 1606.0 |
| DLG1 | -1980.0 | 6587.0 |
| DMAC2L | 1623.0 | -997.0 |
| DNM1L | -4825.0 | 8774.0 |
| DPP8 | -5963.0 | 7906.0 |
| EFHC2 | 4459.0 | 3227.0 |
| EIF3E | -4677.0 | 8580.0 |
| ENDOD1 | -1447.0 | 6234.0 |
| F13A1 | 3019.0 | 4962.0 |
| FHL1 | -7087.0 | 1776.0 |
| GDI2 | -5894.0 | 8074.0 |
| GLG1 | -3103.0 | 2134.0 |
| GMPS | -5160.0 | 8238.0 |
| GNAZ | -1947.0 | 4122.0 |
| GNG11 | -2960.0 | 5884.0 |
| GUCY1A1 | 1918.0 | 7519.0 |
| GUCY1B1 | -1671.0 | 7666.0 |
| HEBP1 | 8031.0 | 1621.0 |
| HGD | -2104.0 | 3212.0 |
| HIGD1A | 359.0 | -3963.0 |
| HLA-DQB1 | -4730.5 | 1217.5 |
| HMGXB4 | -4852.0 | 3401.0 |
| HTATIP2 | -3984.0 | -543.0 |
| IGF2BP3 | -2484.0 | -3959.0 |
| IGFBP7 | -655.0 | -4154.0 |
| IK | -4011.0 | 8357.0 |
| IL12RB2 | 28.0 | -159.0 |
| IL1A | -1142.0 | 1688.0 |
| IQCG | -2680.0 | -3706.0 |
| ITGA2B | 4961.0 | -4170.0 |
| ITGB5 | 7359.0 | 1316.0 |
| JTB | -4066.5 | 5444.5 |
| KCMF1 | -2107.0 | 6464.0 |
| KIAA0319L | 3653.0 | -1408.0 |
| KIF11 | 4262.0 | -1098.0 |
| KLC1 | 143.0 | -5336.0 |
| KYAT3 | 4242.0 | 3058.0 |
| LAP3 | -7119.0 | 4235.0 |
| LEPROT | 7343.0 | -34.0 |
| LPP | 7785.0 | 3122.0 |
| LY6H | 2837.0 | -6470.0 |
| LY86 | -3524.0 | 1844.0 |
| MAPKAPK5 | 1373.0 | 5493.0 |
| MCCC1 | -5695.0 | 1708.0 |
| MCTS1 | 761.0 | 2624.0 |
| MCUR1 | -1414.0 | 1795.0 |
| ME2 | 6693.0 | 6628.0 |
| MFAP3L | -7327.0 | 6664.0 |
| MGLL | 8090.0 | 5435.0 |
| MMD | 6600.0 | 8128.0 |
| MRPS10 | 4929.0 | 5018.0 |
| MRPS15 | 2010.0 | 4604.0 |
| MSH3 | 1132.0 | -2806.0 |
| MTARC2 | 7913.0 | 384.0 |
| MXI1 | -2377.0 | 3008.0 |
| MYG1 | -658.0 | -3758.0 |
| MYH6 | 832.0 | 4629.0 |
| MYL9 | 3189.0 | 8125.0 |
| MYLK | -7270.0 | 6685.0 |
| NACA | -4169.0 | 8236.0 |
| NCAM1 | -2962.0 | 3965.0 |
| NCOA2 | -5757.0 | 5994.0 |
| NDRG2 | -6784.0 | 2803.0 |
| NDUFA9 | 3756.0 | -5331.0 |
| NDUFB5 | 450.0 | 2312.0 |
| NDUFS4 | 4791.0 | 4043.0 |
| NENF | -131.0 | -4804.0 |
| NREP | -6794.0 | 428.0 |
| NRGN | -4483.0 | 579.0 |
| OLA1 | -105.0 | 6435.0 |
| OXA1L | 4609.0 | -4940.0 |
| P2RX7 | 4651.0 | 4591.0 |
| PABPC1 | -949.0 | 6861.0 |
| PARL | 7047.5 | 2790.5 |
| PBX3 | 3107.0 | 6986.0 |
| PDGFA | 4317.0 | 4142.0 |
| PEX26 | 6929.0 | -6742.0 |
| PFDN5 | 2482.0 | 8089.0 |
| PGRMC1 | 8184.0 | 7942.0 |
| PLPBP | -1323.0 | 520.0 |
| PPBP | -5336.0 | 4394.0 |
| PRKAR2B | -2382.0 | -990.0 |
| PROS1 | 4907.0 | 7279.0 |
| PSMA1 | -6705.0 | 7838.0 |
| PSMA6 | -1954.0 | 8445.0 |
| PSMD2 | -6702.0 | -3836.0 |
| PSME1 | 2907.0 | 5905.0 |
| PSTPIP2 | 7077.0 | 1913.0 |
| PTER | -4312.0 | 3141.0 |
| PTGIR | -5223.0 | 4227.0 |
| PTGS1 | 5729.0 | 6228.0 |
| PTP4A2 | 3118.0 | 8121.0 |
| RAB9A | -412.0 | 7818.0 |
| RBBP6 | 3444.0 | 5157.0 |
| REPS1 | 1567.0 | 6807.0 |
| RFTN1 | -5652.0 | 7575.0 |
| RNASEH1 | 2749.5 | -5225.5 |
| RNF115 | -528.0 | 6398.0 |
| RO60 | 3028.0 | 8186.0 |
| RRAGC | -2715.0 | 5320.0 |
| RWDD1 | -3923.0 | 7824.0 |
| S100A10 | 7779.0 | 5985.0 |
| SCAF4 | -1040.0 | -4854.0 |
| SEPTIN2 | -3438.0 | 8730.0 |
| SERINC3 | -4809.0 | 7490.0 |
| SERP1 | -6709.0 | 8229.0 |
| SERTAD2 | 5977.0 | 1740.0 |
| SFXN1 | 3455.0 | 7139.0 |
| SKAP2 | 4178.0 | 4558.0 |
| SLC25A5 | 7651.0 | 6887.0 |
| SMAD1 | 5880.0 | 5459.0 |
| SMAD2 | 2671.0 | 7154.0 |
| SMAD7 | -2050.0 | -4957.0 |
| SMG1 | -4496.0 | 2722.0 |
| SNX4 | 3343.0 | 8400.0 |
| SNX6 | -7210.0 | 1661.0 |
| SOX4 | -2131.0 | 5537.0 |
| STX8 | 475.0 | 5557.0 |
| STYXL1 | 5516.0 | -5386.0 |
| SUCLG1 | 1641.0 | 7641.0 |
| SUMO3 | -7259.0 | 7825.0 |
| TAOK3 | 2465.0 | -3763.0 |
| TAP2 | 5211.5 | -5555.5 |
| TAX1BP1 | 3157.0 | 7948.0 |
| TDRD3 | 1578.0 | 4847.0 |
| TENT5A | -6948.0 | 8031.0 |
| TEP1 | 7484.0 | -6128.0 |
| TMEM8B | 6623.0 | -4550.0 |
| TMEM97 | 7621.0 | 4661.0 |
| TNIK | 2227.0 | 4457.0 |
| TPM1 | -4012.0 | 6903.0 |
| TRIAP1 | 1250.0 | 184.0 |
| TUBB1 | -954.0 | 3430.0 |
| UBE2D2 | -935.0 | 6690.0 |
| UBE2L3 | -4226.5 | 5465.5 |
| UCHL3 | -5410.0 | 8491.0 |
| UGP2 | -6121.0 | 8636.0 |
| UQCRB | -410.0 | 8334.0 |
| UQCRC2 | 2236.0 | 6852.0 |
| VCL | -4796.0 | 7947.0 |
| XAF1 | -6155.0 | 1910.0 |
| XK | -1266.0 | 5749.0 |
| YARS1 | -6414.0 | 4044.0 |
| ZBTB16 | 2742.0 | 1122.0 |
| ZBTB20 | -6766.0 | -328.0 |
| ZMAT3 | 8229.0 | -3189.0 |
| ZNF185 | 8131.0 | 3947.0 |
| ZNF277 | -6016.0 | 4145.0 |
BAELDE_DIABETIC_NEPHROPATHY_DN
| metric | value |
|---|---|
| setSize | 418 |
| pMANOVA | 8.12e-24 |
| p.adjustMANOVA | 3e-22 |
| s.dist | 0.298 |
| s.diabetes | -0.047 |
| s.mitoG | 0.294 |
| p.diabetes | 0.1 |
| p.mitoG | 7.25e-25 |
| Gene | diabetes | mitoG |
|---|---|---|
| HSP90AA1 | -7286 | 8742 |
| CAMSAP2 | -7075 | 8823 |
| HNRNPC | -7051 | 8787 |
| HNRNPA3 | -6985 | 8827 |
| HSP90B1 | -7279 | 8368 |
| CANX | -6936 | 8532 |
| NEK7 | -6954 | 8505 |
| SKP1 | -6803 | 8394 |
| PDIA3 | -7283 | 7821 |
| HSPA5 | -7309 | 7589 |
| UGP2 | -6121 | 8636 |
| RDX | -6580 | 7989 |
| RAD23B | -6778 | 7740 |
| DNAJB9 | -6535 | 8004 |
| SDC2 | -6850 | 7623 |
| RNF11 | -7128 | 7320 |
| RAB1A | -6571 | 7889 |
| HPGD | -6103 | 8382 |
| ARID5B | -7136 | 7137 |
| NAB1 | -5905 | 8617 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| AASDHPPT | 1006.0 | -284.0 |
| AASS | -5588.0 | 6592.0 |
| ABI1 | -4630.0 | 8305.0 |
| ACADM | -6050.0 | 5877.0 |
| ACBD3 | -2828.0 | 5524.0 |
| ACSL3 | 4910.0 | 5105.0 |
| ACTG1 | -1502.0 | 1482.0 |
| ACTR3 | -3716.0 | 8206.0 |
| ADD3 | -5576.0 | 3921.0 |
| ADM | 7469.0 | 6606.0 |
| ADORA1 | 6853.0 | 1954.0 |
| AGRN | -2966.0 | -6131.0 |
| AIF1 | -4099.0 | 2383.0 |
| AKAP10 | -5977.0 | -1227.0 |
| AKAP11 | -1764.0 | 6756.0 |
| ALDH3B1 | 7287.0 | 4258.0 |
| ANXA1 | 7055.0 | 8221.0 |
| AP3B1 | 3159.0 | 1998.0 |
| APOD | 7042.0 | 5748.0 |
| APOL1 | -5660.5 | 2701.5 |
| AQP3 | 6699.0 | 3015.0 |
| ARHGAP19 | 3282.5 | 2517.5 |
| ARHGAP5 | -4817.0 | 8593.0 |
| ARHGEF18 | 5858.5 | -119.5 |
| ARID5B | -7136.0 | 7137.0 |
| ARL1 | -4284.0 | 8747.0 |
| ARMCX2 | -127.0 | 6066.0 |
| ATP13A3 | -6713.0 | 1547.0 |
| ATP2A2 | -7302.0 | 1164.0 |
| ATP6AP2 | 596.0 | 3605.0 |
| ATP7A | -3222.0 | 7692.0 |
| ATP9A | 2751.0 | -5901.0 |
| ATXN1 | 5463.0 | -5164.0 |
| ATXN10 | 5458.0 | 7404.0 |
| AXL | 2690.0 | 8077.0 |
| B4GAT1 | 7224.0 | -6185.0 |
| BCAM | 7750.0 | 2432.0 |
| BCAR3 | 5770.0 | 4210.0 |
| BEX4 | -5280.0 | -299.0 |
| BIRC2 | -4230.0 | 3665.0 |
| BIRC3 | 6091.0 | 6158.0 |
| BMP2 | 4300.0 | 7938.0 |
| BMP7 | 8109.0 | -1080.0 |
| BST2 | -460.0 | -4229.0 |
| C1R | 1107.0 | 6557.0 |
| C1S | 644.0 | 7556.0 |
| CACNB2 | 5838.0 | -5134.0 |
| CALD1 | -3883.0 | 8801.0 |
| CALM2 | 4763.0 | 8625.0 |
| CALU | -3535.0 | 8715.0 |
| CAMSAP2 | -7075.0 | 8823.0 |
| CAND2 | 6037.0 | -3746.0 |
| CANX | -6936.0 | 8532.0 |
| CAPN2 | 5357.0 | 7435.0 |
| CASP1 | -1051.0 | 1558.0 |
| CAST | 3920.0 | 8492.0 |
| CBLB | -3155.0 | 5963.0 |
| CCDC6 | -7278.0 | -704.0 |
| CCN1 | -4142.0 | 4431.0 |
| CCN2 | 4056.0 | 8456.0 |
| CD164 | 4917.0 | 4249.0 |
| CD200 | 5072.0 | 7059.0 |
| CD2AP | 1296.0 | 8225.0 |
| CD47 | -1991.0 | 7809.0 |
| CD55 | -6863.0 | 6749.0 |
| CDC14A | -366.0 | 4455.0 |
| CDC42EP3 | -2134.0 | 8017.0 |
| CDKN1C | 8161.0 | 5620.0 |
| CDS1 | 7794.0 | 278.0 |
| CDV3 | 6007.0 | 6969.0 |
| CEBPD | 3288.0 | 6984.0 |
| CERS6 | -1584.0 | 1516.0 |
| CFLAR | -4054.0 | 2224.0 |
| CHD3 | -7230.0 | -2465.0 |
| CHI3L1 | 3964.0 | 708.0 |
| CHST2 | 2012.0 | 6764.0 |
| CITED2 | -1285.0 | 2778.0 |
| CLEC16A | -3534.0 | 4164.0 |
| CLIC5 | 1754.0 | 4129.0 |
| CLIP3 | 6391.0 | 383.0 |
| COL3A1 | -2073.0 | 3836.0 |
| COL4A3 | -7009.0 | 2651.0 |
| COL4A4 | -7080.0 | -2678.0 |
| COL4A6 | -3205.0 | 1099.0 |
| COLQ | 5431.0 | -3281.0 |
| CORO2B | 4667.0 | 6811.0 |
| CR1 | -4680.0 | 4418.0 |
| CREB3L2 | -2683.0 | -4241.0 |
| CRIM1 | 425.0 | 5416.0 |
| CTBP1 | 2741.0 | -5332.0 |
| CTDSPL | -6769.0 | -3198.0 |
| CTNNA1 | 2129.0 | 7795.0 |
| CTNNBIP1 | 2783.0 | -1863.0 |
| CXADR | -7100.0 | 3254.0 |
| CYP1B1 | 7373.0 | 8462.0 |
| CYP51A1 | 39.0 | -254.0 |
| DAG1 | 6646.0 | 3480.0 |
| DCAF8 | 32.0 | -4825.0 |
| DCTD | -3347.0 | 491.0 |
| DDN | 6361.0 | 876.0 |
| DDX17 | -6389.0 | -6574.0 |
| DLG5 | 7242.0 | -2644.0 |
| DNAJA1 | -7303.0 | 6518.0 |
| DNAJB9 | -6535.0 | 8004.0 |
| DNM1L | -4825.0 | 8774.0 |
| DPP6 | 2037.0 | 1202.0 |
| DPYSL3 | -516.0 | 3651.0 |
| DST | 1303.0 | 1938.0 |
| DSTN | 3956.0 | 8525.0 |
| DUSP1 | -2905.0 | -1666.0 |
| DUSP14 | 3618.0 | -3426.0 |
| DYRK1A | 692.0 | 5205.0 |
| ECM2 | 4746.0 | 2978.0 |
| EFR3A | -4691.0 | 7308.0 |
| EID1 | -5024.0 | 6090.0 |
| EIF3M | -2954.0 | 7258.0 |
| EIF4A2 | -6848.0 | -699.0 |
| ELF2 | 2203.0 | 5901.0 |
| ENPEP | 7508.0 | 2528.0 |
| EPS15 | -5197.0 | 5904.0 |
| ERBB4 | 2718.0 | 2425.0 |
| EXPH5 | 1020.0 | 7614.0 |
| F2R | 7855.0 | 8597.0 |
| F3 | 3208.0 | 6573.0 |
| F8A1 | 4778.0 | -4244.0 |
| FAM98A | -6507.0 | 4863.0 |
| FAT1 | -697.0 | 5764.0 |
| FBXO21 | 8209.0 | -5962.0 |
| FERMT2 | 5215.0 | 7566.0 |
| FGF1 | -6961.0 | 3296.0 |
| FGF9 | 2653.0 | -2366.0 |
| FGFR2 | 6750.0 | 6454.0 |
| FLNA | -4704.0 | 7432.0 |
| FLRT2 | -5140.0 | 5982.0 |
| FNBP1 | -4982.0 | -2153.0 |
| FNBP1L | 3122.0 | 4349.0 |
| FOSL2 | 3909.0 | 5473.0 |
| FOXC1 | 5241.0 | -2301.0 |
| FRY | 7273.0 | 6809.0 |
| FYN | -2200.0 | 6221.0 |
| G0S2 | 4904.0 | 8051.0 |
| GAB2 | -717.0 | 7438.0 |
| GADD45A | -1190.0 | 1738.0 |
| GALC | -3406.0 | -365.0 |
| GAS1 | 7552.0 | -2009.0 |
| GDE1 | 5901.0 | 6082.0 |
| GHR | -6922.0 | 4790.0 |
| GJA1 | -2103.0 | -4151.0 |
| GJA5 | 1705.0 | 2064.0 |
| GLOD4 | 1193.0 | 3577.0 |
| GLUD2 | 8064.5 | 3730.5 |
| GLUL | 7900.0 | 3064.0 |
| GMDS | 3172.0 | 2992.0 |
| GMFB | -2893.0 | 4192.0 |
| GNE | 5717.0 | 4001.0 |
| GPNMB | 2911.0 | -314.0 |
| GPRC5A | -2287.0 | 6401.0 |
| GRIK2 | -1574.0 | -5818.0 |
| GRK5 | 280.0 | 5528.0 |
| GTF2A2 | 505.0 | 6107.0 |
| GULP1 | 3722.0 | 7458.0 |
| GYG1 | 27.0 | 6415.0 |
| HIRA | -6015.0 | -99.0 |
| HMCES | -1723.0 | -1024.0 |
| HMGN1 | -2290.0 | -3911.0 |
| HMGN3 | 4379.0 | 6414.0 |
| HNRNPA1 | 7891.0 | -6290.0 |
| HNRNPA3 | -6985.0 | 8827.0 |
| HNRNPC | -7051.0 | 8787.0 |
| HNRNPDL | 8075.0 | 2325.0 |
| HOXA9 | 3263.0 | 751.0 |
| HPGD | -6103.0 | 8382.0 |
| HSP90AA1 | -7286.0 | 8742.0 |
| HSP90B1 | -7279.0 | 8368.0 |
| HSPA12A | -4571.0 | 1589.0 |
| HSPA2 | 7012.0 | 5387.0 |
| HSPA5 | -7309.0 | 7589.0 |
| HSPB11 | 3987.0 | -4435.0 |
| HTRA1 | -6975.0 | 1980.0 |
| IARS1 | -5409.0 | 3400.0 |
| IFI35 | 236.0 | -2661.0 |
| IFI44 | -5838.0 | 5940.0 |
| IFITM1 | 6414.0 | 8796.0 |
| IGFBP2 | 3766.0 | -1385.0 |
| IGFBP7 | -655.0 | -4154.0 |
| ING1 | 2867.0 | 3245.0 |
| IQGAP2 | 8068.0 | 6890.0 |
| IRS1 | 7064.0 | -5549.0 |
| ISG15 | -1124.0 | -2998.0 |
| ITGA3 | 6960.0 | 5200.0 |
| ITGAV | 8155.0 | 2693.0 |
| ITGB5 | 7359.0 | 1316.0 |
| KANK1 | -2615.0 | -1388.0 |
| KBTBD11 | -5302.0 | -5124.0 |
| KCND3 | -5750.0 | 7222.0 |
| KIAA0232 | -2998.0 | 4724.0 |
| KIF5B | -1547.0 | 8819.0 |
| KLHL9 | -5268.0 | 6137.0 |
| LANCL1 | 6816.0 | -5515.0 |
| LEPROT | 7343.0 | -34.0 |
| LETMD1 | 5401.0 | -3080.0 |
| LITAF | 8063.0 | 5645.0 |
| LOX | 7282.0 | 7922.0 |
| LOXL1 | 6829.0 | 8361.0 |
| LPL | -7356.0 | 1308.0 |
| LRIG1 | 4468.0 | -2718.0 |
| LSR | -5031.0 | 150.0 |
| LUC7L3 | -5772.0 | 3514.0 |
| MAFF | 4078.0 | 3523.0 |
| MAGI2 | 2368.0 | -2330.0 |
| MCL1 | 6260.0 | -1020.0 |
| MCM6 | -6774.0 | 5231.0 |
| MECP2 | 7588.0 | -950.0 |
| MED21 | -6615.0 | 7431.0 |
| MEGF9 | 6504.0 | 6830.0 |
| MGAT5 | -6087.0 | 2955.0 |
| MME | -2831.0 | 3783.0 |
| MORC3 | -4342.0 | 8071.0 |
| MSH2 | 7784.0 | -3657.0 |
| MTDH | 2225.0 | 8064.0 |
| MTHFD2 | 741.0 | 6092.0 |
| MTSS1 | -4717.0 | -2278.0 |
| MTX2 | 620.0 | 2417.0 |
| MXRA8 | -35.0 | 8623.0 |
| MYH9 | 7189.0 | 7115.0 |
| MYL9 | 3189.0 | 8125.0 |
| MYLK | -7270.0 | 6685.0 |
| MYO1B | 1208.0 | 6584.0 |
| MYO1E | -1541.0 | -3326.0 |
| N4BP1 | -5080.0 | 168.0 |
| N4BP2L1 | 6596.0 | -3936.0 |
| NAB1 | -5905.0 | 8617.0 |
| NAMPT | 8078.0 | 8082.0 |
| NAPG | 3323.0 | 2180.0 |
| NBN | -5298.0 | 8349.0 |
| NDN | 894.0 | 5072.0 |
| NDRG1 | -6340.0 | 1937.0 |
| NECTIN2 | 8037.0 | -2727.0 |
| NEDD9 | 6142.0 | 8318.0 |
| NEK7 | -6954.0 | 8505.0 |
| NFASC | -6650.0 | -793.0 |
| NFATC3 | -5299.0 | 6496.0 |
| NFE2L1 | 7245.0 | 5542.0 |
| NMI | 5088.0 | -2764.0 |
| NPHS1 | 8004.0 | 2268.0 |
| NPTN | 2459.0 | 6839.0 |
| NR3C1 | -2732.0 | 2240.0 |
| NTRK2 | -2163.0 | 86.0 |
| NUPR1 | 6698.0 | 7199.0 |
| OAS1 | 3456.0 | -6726.0 |
| OAS2 | -6685.0 | -1827.0 |
| ODC1 | -7155.0 | 3068.0 |
| OPTN | 8052.0 | 6703.0 |
| OSER1 | 253.0 | 7396.0 |
| OSMR | 5259.0 | 8374.0 |
| OTUD4 | -4844.0 | 7588.0 |
| PAFAH1B1 | -3995.0 | 8266.0 |
| PAK1 | -886.0 | 5458.0 |
| PALLD | -5124.0 | -1144.0 |
| PAM | 2452.0 | 1723.0 |
| PAPSS1 | -2058.0 | 4960.0 |
| PARD3 | -6499.0 | -3064.0 |
| PARP1 | 134.0 | 473.0 |
| PAWR | -2539.0 | -5771.0 |
| PCK1 | 6911.0 | 5688.0 |
| PCMT1 | 766.0 | 5209.0 |
| PDE4B | 4858.0 | 7349.0 |
| PDE4DIP | 3763.0 | 6688.0 |
| PDGFA | 4317.0 | 4142.0 |
| PDIA3 | -7283.0 | 7821.0 |
| PDLIM5 | 5446.0 | 6613.0 |
| PEX14 | 5317.0 | 5271.0 |
| PFN2 | 701.0 | 4388.0 |
| PHLPP2 | -4039.0 | -122.0 |
| PHYHIP | 7368.0 | -464.0 |
| PLA2R1 | -6067.0 | 7483.0 |
| PLCE1 | 6100.0 | 6421.0 |
| PLCG2 | -5287.0 | 2474.0 |
| PLOD2 | -7324.0 | 3272.0 |
| PLS3 | -984.0 | 8476.0 |
| PLSCR1 | -6591.0 | -6700.0 |
| PLXNB2 | 3319.0 | -3714.0 |
| PNMA2 | -2141.0 | 2522.0 |
| PODXL | 4742.0 | 7498.0 |
| POSTN | -1531.0 | -1183.0 |
| PPFIA4 | -4548.0 | -3282.0 |
| PPP2CB | 5588.0 | 159.0 |
| PRDX6 | -3287.0 | 3877.0 |
| PREPL | -6206.0 | 2850.0 |
| PRKACB | 569.0 | 661.0 |
| PRKAR1A | 3942.0 | 6647.0 |
| PRKAR2B | -2382.0 | -990.0 |
| PRKCI | -1288.0 | 1225.0 |
| PSMA2 | -5464.5 | 6058.5 |
| PSMA3 | -3145.0 | 7801.0 |
| PSMA6 | -1954.0 | 8445.0 |
| PSMB9 | 5987.0 | -4708.0 |
| PTGDS | 4285.5 | -1738.5 |
| PTGER4 | 2504.0 | 1265.0 |
| PTH1R | -5755.0 | -4442.0 |
| PTPN11 | -3946.0 | 6142.0 |
| PTPN14 | 5809.0 | 5132.0 |
| PTPN7 | -1757.0 | -3829.0 |
| PTPRD | 5666.0 | -327.0 |
| PTPRO | 6948.0 | 4311.0 |
| RAB1A | -6571.0 | 7889.0 |
| RAB21 | -2903.0 | 7574.0 |
| RABGAP1L | 4836.0 | 6327.0 |
| RAD23B | -6778.0 | 7740.0 |
| RAI14 | 485.0 | 5278.0 |
| RARRES2 | 2602.0 | -1260.0 |
| RBBP4 | -6148.0 | 5835.0 |
| RBMS1 | -4349.0 | 7009.0 |
| RCAN1 | 4520.0 | 2536.0 |
| RDX | -6580.0 | 7989.0 |
| RGS10 | -3271.0 | 4787.0 |
| RHOBTB2 | 4866.0 | -6217.0 |
| RNF11 | -7128.0 | 7320.0 |
| RPN2 | -5521.0 | 3974.0 |
| RSBN1 | 6236.0 | 5447.0 |
| SACM1L | 643.0 | 5177.0 |
| SARAF | -5234.0 | 1625.0 |
| SART3 | 1001.0 | -2834.0 |
| SCHIP1 | 3002.5 | -1115.5 |
| SCRN1 | 5367.0 | 1189.0 |
| SDC2 | -6850.0 | 7623.0 |
| SDC4 | 6585.0 | 816.0 |
| SEC61G | -2855.0 | 8720.0 |
| SEMA3B | 7901.0 | -5165.0 |
| SEMA3C | -6483.0 | 2704.0 |
| SEMA5A | -5557.0 | 182.0 |
| SEPTIN10 | 4833.0 | 4380.0 |
| SEPTIN11 | 3452.0 | 5629.0 |
| SEPTIN2 | -3438.0 | 8730.0 |
| SERINC1 | -5903.0 | 6313.0 |
| SERINC5 | 7586.0 | 448.0 |
| SERPINE1 | 2322.0 | 8202.0 |
| SET | -4660.5 | 2403.5 |
| SGMS1 | -3278.0 | 3419.0 |
| SKP1 | -6803.0 | 8394.0 |
| SLK | 8080.0 | 6197.0 |
| SMARCA2 | -7342.0 | 1064.0 |
| SMARCC1 | -4379.0 | 5036.0 |
| SNX19 | 15.0 | 855.0 |
| SPOCK2 | 5213.0 | 2612.0 |
| SRGAP2 | -1169.0 | -688.0 |
| SSBP2 | 440.0 | 2334.0 |
| ST3GAL6 | 774.0 | 7961.0 |
| STAT1 | -3464.0 | -4440.0 |
| STX7 | -3784.0 | 8359.0 |
| SUB1 | 80.0 | 7679.0 |
| SULF1 | 3980.0 | 4112.0 |
| SULT1A2 | 3145.5 | -3951.5 |
| SYNPO | 7369.0 | 5900.0 |
| TAP1 | 5427.0 | -6060.0 |
| TAPBP | 6125.0 | -2067.0 |
| TAX1BP1 | 3157.0 | 7948.0 |
| TBC1D9B | 471.0 | 2911.0 |
| TBCA | -3096.0 | 8543.0 |
| TCF21 | 1353.0 | 4314.0 |
| TEAD4 | -292.0 | 7230.0 |
| TGFBR3 | 7234.0 | 4931.0 |
| THSD7A | 2585.0 | 6050.0 |
| TIAL1 | -5851.0 | 3033.0 |
| TIMP1 | -2454.0 | 3444.0 |
| TLE4 | 3151.0 | 4968.0 |
| TLK1 | -4064.0 | 8347.0 |
| TMED10 | -6147.0 | 6432.0 |
| TMED5 | -2795.0 | 8686.0 |
| TMEM123 | 5152.0 | 7162.0 |
| TMEM259 | -1139.0 | -4368.0 |
| TMX4 | 4757.0 | 3264.0 |
| TNNT2 | 4843.0 | -2318.0 |
| TOB1 | 1023.0 | 6857.0 |
| TOM1L2 | 7414.0 | -6586.0 |
| TOMM20 | 7388.0 | 3171.0 |
| TOMM34 | -4482.0 | -2240.0 |
| TOP2B | -411.0 | 8373.0 |
| TRAM2 | -6493.0 | 4494.0 |
| TRIB2 | -6029.0 | 3313.0 |
| TRIM22 | 773.0 | 258.0 |
| TRIM23 | 4542.0 | 6848.0 |
| TRIM37 | -6310.0 | -2309.0 |
| TRIM44 | -6012.0 | 7523.0 |
| TSC22D3 | 1663.0 | 5520.0 |
| TSPAN3 | -1044.0 | 865.0 |
| TSPYL4 | -3810.0 | 108.0 |
| TUBB2A | 1093.0 | 8351.0 |
| TUSC3 | -5686.0 | 4758.0 |
| TYRO3 | 7595.0 | 256.0 |
| UAP1 | -7245.0 | 1255.0 |
| UBE2D2 | -935.0 | 6690.0 |
| UBE2L6 | 809.0 | 5322.0 |
| UBR2 | -6912.0 | -5650.0 |
| UGCG | -6237.0 | 4297.0 |
| UGP2 | -6121.0 | 8636.0 |
| ULK2 | -6626.0 | 600.0 |
| UNG | 6140.0 | -32.0 |
| USP46 | -5840.0 | 8296.0 |
| USP9X | -5668.0 | 7709.0 |
| VCAN | -3773.0 | 1454.0 |
| VEGFA | -4619.0 | -5156.0 |
| VIM | 5500.0 | 7940.0 |
| VPS13D | -414.0 | 3107.0 |
| VPS26A | -1189.0 | 7049.0 |
| WARS1 | 2233.0 | 2888.0 |
| WT1 | 5237.0 | 3586.0 |
| WWP1 | -6879.0 | 6537.0 |
| XBP1 | -7174.0 | 6737.0 |
| XPO1 | -6543.0 | 7447.0 |
| XRCC5 | -2388.0 | 162.0 |
| YBX3 | 5916.0 | 4090.0 |
| YWHAE | -2079.0 | 7315.0 |
| YWHAZ | -5614.0 | 8512.0 |
| ZBTB20 | -6766.0 | -328.0 |
| ZC3HAV1 | -469.0 | -613.0 |
| ZNF185 | 8131.0 | 3947.0 |
| ZNF516 | 6822.0 | 1958.0 |
HP_MATERNAL_DIABETES
| metric | value |
|---|---|
| setSize | 21 |
| pMANOVA | 0.0543 |
| p.adjustMANOVA | 0.0913 |
| s.dist | 0.291 |
| s.diabetes | -0.0316 |
| s.mitoG | -0.289 |
| p.diabetes | 0.802 |
| p.mitoG | 0.0218 |
| Gene | diabetes | mitoG |
|---|---|---|
| SUFU | -4804 | -5489 |
| SHH | -4143 | -5003 |
| GJA1 | -2103 | -4151 |
| DLL1 | -4076 | -1816 |
| PROKR2 | -2068 | -3287 |
| FUZ | -928 | -5631 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| ARNT2 | 8205.0 | 310.0 |
| CDON | -5264.0 | 357.0 |
| CLCNKB | 8258.5 | -2053.5 |
| DISP1 | 1277.0 | -673.0 |
| DLL1 | -4076.0 | -1816.0 |
| ERGIC1 | -6556.0 | 5268.0 |
| FGFR1 | 6753.0 | -812.0 |
| FUZ | -928.0 | -5631.0 |
| GAS1 | 7552.0 | -2009.0 |
| GJA1 | -2103.0 | -4151.0 |
| GLI2 | -1482.0 | 794.0 |
| HESX1 | 5292.0 | -1586.0 |
| KCNJ11 | 2961.0 | -3265.0 |
| PPARG | -3636.0 | 5654.0 |
| PROKR2 | -2068.0 | -3287.0 |
| PTCH1 | 2844.0 | -1386.0 |
| SHH | -4143.0 | -5003.0 |
| SLC12A3 | 6051.0 | -4654.0 |
| SUFU | -4804.0 | -5489.0 |
| TGIF1 | -4370.0 | 895.0 |
| VANGL1 | -5326.0 | 2768.0 |
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
| metric | value |
|---|---|
| setSize | 120 |
| pMANOVA | 5.69e-08 |
| p.adjustMANOVA | 3.51e-07 |
| s.dist | 0.274 |
| s.diabetes | 0.238 |
| s.mitoG | 0.137 |
| p.diabetes | 6.91e-06 |
| p.mitoG | 0.00966 |
| Gene | diabetes | mitoG |
|---|---|---|
| COX7B | 6102.0 | 8760.0 |
| ATP5PO | 6640.5 | 7456.5 |
| UQCRQ | 6271.0 | 7840.0 |
| MT-ND5 | 6025.0 | 8007.0 |
| MT-ND1 | 5618.0 | 7323.0 |
| MT-ND6 | 5059.0 | 8045.0 |
| MT-CO1 | 6781.0 | 5983.0 |
| COX6B1 | 5091.0 | 7299.0 |
| NDUFA6 | 6990.0 | 5257.0 |
| NDUFA12 | 4539.0 | 8087.0 |
| NDUFV2 | 4127.0 | 8731.0 |
| NDUFB8 | 4901.5 | 6790.5 |
| UCP2 | 6987.0 | 4595.0 |
| ATP5PD | 5135.0 | 6133.0 |
| NDUFA7 | 7477.5 | 4100.5 |
| MT-CYB | 3577.0 | 8110.0 |
| LRPPRC | 3831.0 | 6319.0 |
| SDHB | 3180.0 | 7355.0 |
| NDUFA8 | 5308.0 | 4366.0 |
| NDUFA5 | 7846.0 | 2875.0 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| ACAD9 | -4848.0 | -2818.0 |
| ATP5F1A | 6316.0 | 1471.0 |
| ATP5F1B | 1691.0 | 1750.0 |
| ATP5F1C | 164.0 | 8242.0 |
| ATP5F1D | 5225.0 | 673.0 |
| ATP5F1E | 6241.0 | -5774.0 |
| ATP5MC3 | 6278.0 | -5724.0 |
| ATP5ME | 3268.0 | 3202.0 |
| ATP5MF | 6860.0 | -1957.0 |
| ATP5MG | 5923.5 | 564.5 |
| ATP5PB | 1124.0 | 5544.0 |
| ATP5PD | 5135.0 | 6133.0 |
| ATP5PF | 710.0 | 7012.0 |
| ATP5PO | 6640.5 | 7456.5 |
| COQ10A | 7831.0 | -5063.0 |
| COQ10B | 219.0 | 7422.0 |
| COX11 | 742.0 | -1169.0 |
| COX14 | 2703.0 | -3376.0 |
| COX16 | -3433.0 | 7416.0 |
| COX18 | 5019.0 | 1575.0 |
| COX19 | -2099.0 | 3124.0 |
| COX20 | -4714.0 | 6792.0 |
| COX4I1 | 6324.0 | -2473.0 |
| COX5B | 7740.0 | -2295.0 |
| COX6A1 | 5658.0 | -2138.0 |
| COX6B1 | 5091.0 | 7299.0 |
| COX6C | 7537.0 | 1755.0 |
| COX7A2L | 4007.0 | 4780.0 |
| COX7B | 6102.0 | 8760.0 |
| COX7C | 4066.0 | -5285.0 |
| COX8A | 5622.0 | -4787.0 |
| CYC1 | 7497.0 | -4809.0 |
| DMAC2L | 1623.0 | -997.0 |
| ECSIT | -3596.0 | 1408.0 |
| ETFA | -4953.0 | 3129.0 |
| ETFB | 5896.0 | -2345.0 |
| ETFDH | -5320.0 | 8131.0 |
| LRPPRC | 3831.0 | 6319.0 |
| MT-ATP6 | -5818.0 | 8744.0 |
| MT-ATP8 | 3277.0 | 6153.0 |
| MT-CO1 | 6781.0 | 5983.0 |
| MT-CO2 | 293.0 | -1711.0 |
| MT-CO3 | 2273.0 | 6269.0 |
| MT-CYB | 3577.0 | 8110.0 |
| MT-ND1 | 5618.0 | 7323.0 |
| MT-ND2 | -1693.0 | 8626.0 |
| MT-ND3 | 1835.0 | 8689.0 |
| MT-ND4 | 1752.0 | 7883.0 |
| MT-ND5 | 6025.0 | 8007.0 |
| MT-ND6 | 5059.0 | 8045.0 |
| NDUFA1 | 2104.0 | -4989.0 |
| NDUFA10 | -1891.0 | 7765.0 |
| NDUFA11 | 7279.5 | 474.5 |
| NDUFA12 | 4539.0 | 8087.0 |
| NDUFA13 | 4768.0 | -2346.0 |
| NDUFA2 | 5261.0 | -6155.0 |
| NDUFA3 | 4319.0 | 82.0 |
| NDUFA4 | -5102.0 | 8096.0 |
| NDUFA5 | 7846.0 | 2875.0 |
| NDUFA6 | 6990.0 | 5257.0 |
| NDUFA7 | 7477.5 | 4100.5 |
| NDUFA8 | 5308.0 | 4366.0 |
| NDUFA9 | 3756.0 | -5331.0 |
| NDUFAB1 | 251.0 | 2742.0 |
| NDUFAF1 | -5470.0 | 1013.0 |
| NDUFAF2 | -2453.0 | 6013.0 |
| NDUFAF3 | -983.0 | -2862.0 |
| NDUFAF4 | -5532.0 | 7346.0 |
| NDUFAF5 | 1712.0 | 1907.0 |
| NDUFAF6 | -2110.0 | -2934.0 |
| NDUFAF7 | 1694.0 | 6697.0 |
| NDUFB1 | 5672.0 | 711.0 |
| NDUFB10 | 4853.0 | -1340.0 |
| NDUFB11 | 1539.0 | 7247.0 |
| NDUFB2 | 2034.0 | -5126.0 |
| NDUFB3 | -2553.0 | -4632.0 |
| NDUFB4 | -5247.0 | 8719.0 |
| NDUFB5 | 450.0 | 2312.0 |
| NDUFB6 | 6783.0 | 848.0 |
| NDUFB7 | 5336.0 | 2347.0 |
| NDUFB8 | 4901.5 | 6790.5 |
| NDUFB9 | 6765.0 | 1224.0 |
| NDUFC1 | 1620.0 | 3968.0 |
| NDUFC2 | 4564.5 | -5546.5 |
| NDUFS1 | -1094.0 | 6402.0 |
| NDUFS2 | 1841.0 | 4991.0 |
| NDUFS3 | 4184.0 | -2145.0 |
| NDUFS4 | 4791.0 | 4043.0 |
| NDUFS5 | 5126.0 | -4249.0 |
| NDUFS6 | 2287.0 | 6500.0 |
| NDUFS7 | 7367.0 | -5947.0 |
| NDUFS8 | 1961.0 | 2910.0 |
| NDUFV1 | 4313.0 | -2431.0 |
| NDUFV2 | 4127.0 | 8731.0 |
| NDUFV3 | -5257.0 | 5625.0 |
| NUBPL | -1636.0 | -1999.0 |
| PM20D1 | -4304.0 | -1376.0 |
| SCO1 | -3365.0 | 57.0 |
| SCO2 | -3687.0 | 2948.0 |
| SDHA | 3626.5 | -1630.5 |
| SDHB | 3180.0 | 7355.0 |
| SDHC | -860.0 | 834.0 |
| SDHD | 6887.5 | 1213.5 |
| SLC25A14 | -1689.0 | -3486.0 |
| SLC25A27 | 1702.0 | -2334.0 |
| SURF1 | 2134.0 | 4131.0 |
| TACO1 | -3888.0 | 3315.0 |
| TIMMDC1 | -2651.0 | -2924.0 |
| TMEM126B | -6725.0 | 3713.0 |
| TRAP1 | -6124.0 | 2675.0 |
| UCP2 | 6987.0 | 4595.0 |
| UCP3 | 3545.0 | -4364.0 |
| UQCR10 | 6187.0 | 697.0 |
| UQCR11 | 5012.5 | -3179.5 |
| UQCRB | -410.0 | 8334.0 |
| UQCRC1 | 5627.0 | 1729.0 |
| UQCRC2 | 2236.0 | 6852.0 |
| UQCRFS1 | 3296.0 | -3981.0 |
| UQCRH | 5780.5 | -5189.5 |
| UQCRQ | 6271.0 | 7840.0 |
Respiratory electron transport
| metric | value |
|---|---|
| setSize | 99 |
| pMANOVA | 2.09e-06 |
| p.adjustMANOVA | 7.73e-06 |
| s.dist | 0.266 |
| s.diabetes | 0.221 |
| s.mitoG | 0.148 |
| p.diabetes | 0.000144 |
| p.mitoG | 0.0112 |
| Gene | diabetes | mitoG |
|---|---|---|
| COX7B | 6102.0 | 8760.0 |
| UQCRQ | 6271.0 | 7840.0 |
| MT-ND5 | 6025.0 | 8007.0 |
| MT-ND1 | 5618.0 | 7323.0 |
| MT-ND6 | 5059.0 | 8045.0 |
| MT-CO1 | 6781.0 | 5983.0 |
| COX6B1 | 5091.0 | 7299.0 |
| NDUFA6 | 6990.0 | 5257.0 |
| NDUFA12 | 4539.0 | 8087.0 |
| NDUFV2 | 4127.0 | 8731.0 |
| NDUFB8 | 4901.5 | 6790.5 |
| NDUFA7 | 7477.5 | 4100.5 |
| MT-CYB | 3577.0 | 8110.0 |
| LRPPRC | 3831.0 | 6319.0 |
| SDHB | 3180.0 | 7355.0 |
| NDUFA8 | 5308.0 | 4366.0 |
| NDUFA5 | 7846.0 | 2875.0 |
| NDUFS4 | 4791.0 | 4043.0 |
| COX7A2L | 4007.0 | 4780.0 |
| MT-ND3 | 1835.0 | 8689.0 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| ACAD9 | -4848.0 | -2818.0 |
| COQ10A | 7831.0 | -5063.0 |
| COQ10B | 219.0 | 7422.0 |
| COX11 | 742.0 | -1169.0 |
| COX14 | 2703.0 | -3376.0 |
| COX16 | -3433.0 | 7416.0 |
| COX18 | 5019.0 | 1575.0 |
| COX19 | -2099.0 | 3124.0 |
| COX20 | -4714.0 | 6792.0 |
| COX4I1 | 6324.0 | -2473.0 |
| COX5B | 7740.0 | -2295.0 |
| COX6A1 | 5658.0 | -2138.0 |
| COX6B1 | 5091.0 | 7299.0 |
| COX6C | 7537.0 | 1755.0 |
| COX7A2L | 4007.0 | 4780.0 |
| COX7B | 6102.0 | 8760.0 |
| COX7C | 4066.0 | -5285.0 |
| COX8A | 5622.0 | -4787.0 |
| CYC1 | 7497.0 | -4809.0 |
| ECSIT | -3596.0 | 1408.0 |
| ETFA | -4953.0 | 3129.0 |
| ETFB | 5896.0 | -2345.0 |
| ETFDH | -5320.0 | 8131.0 |
| LRPPRC | 3831.0 | 6319.0 |
| MT-CO1 | 6781.0 | 5983.0 |
| MT-CO2 | 293.0 | -1711.0 |
| MT-CO3 | 2273.0 | 6269.0 |
| MT-CYB | 3577.0 | 8110.0 |
| MT-ND1 | 5618.0 | 7323.0 |
| MT-ND2 | -1693.0 | 8626.0 |
| MT-ND3 | 1835.0 | 8689.0 |
| MT-ND4 | 1752.0 | 7883.0 |
| MT-ND5 | 6025.0 | 8007.0 |
| MT-ND6 | 5059.0 | 8045.0 |
| NDUFA1 | 2104.0 | -4989.0 |
| NDUFA10 | -1891.0 | 7765.0 |
| NDUFA11 | 7279.5 | 474.5 |
| NDUFA12 | 4539.0 | 8087.0 |
| NDUFA13 | 4768.0 | -2346.0 |
| NDUFA2 | 5261.0 | -6155.0 |
| NDUFA3 | 4319.0 | 82.0 |
| NDUFA4 | -5102.0 | 8096.0 |
| NDUFA5 | 7846.0 | 2875.0 |
| NDUFA6 | 6990.0 | 5257.0 |
| NDUFA7 | 7477.5 | 4100.5 |
| NDUFA8 | 5308.0 | 4366.0 |
| NDUFA9 | 3756.0 | -5331.0 |
| NDUFAB1 | 251.0 | 2742.0 |
| NDUFAF1 | -5470.0 | 1013.0 |
| NDUFAF2 | -2453.0 | 6013.0 |
| NDUFAF3 | -983.0 | -2862.0 |
| NDUFAF4 | -5532.0 | 7346.0 |
| NDUFAF5 | 1712.0 | 1907.0 |
| NDUFAF6 | -2110.0 | -2934.0 |
| NDUFAF7 | 1694.0 | 6697.0 |
| NDUFB1 | 5672.0 | 711.0 |
| NDUFB10 | 4853.0 | -1340.0 |
| NDUFB11 | 1539.0 | 7247.0 |
| NDUFB2 | 2034.0 | -5126.0 |
| NDUFB3 | -2553.0 | -4632.0 |
| NDUFB4 | -5247.0 | 8719.0 |
| NDUFB5 | 450.0 | 2312.0 |
| NDUFB6 | 6783.0 | 848.0 |
| NDUFB7 | 5336.0 | 2347.0 |
| NDUFB8 | 4901.5 | 6790.5 |
| NDUFB9 | 6765.0 | 1224.0 |
| NDUFC1 | 1620.0 | 3968.0 |
| NDUFC2 | 4564.5 | -5546.5 |
| NDUFS1 | -1094.0 | 6402.0 |
| NDUFS2 | 1841.0 | 4991.0 |
| NDUFS3 | 4184.0 | -2145.0 |
| NDUFS4 | 4791.0 | 4043.0 |
| NDUFS5 | 5126.0 | -4249.0 |
| NDUFS6 | 2287.0 | 6500.0 |
| NDUFS7 | 7367.0 | -5947.0 |
| NDUFS8 | 1961.0 | 2910.0 |
| NDUFV1 | 4313.0 | -2431.0 |
| NDUFV2 | 4127.0 | 8731.0 |
| NDUFV3 | -5257.0 | 5625.0 |
| NUBPL | -1636.0 | -1999.0 |
| SCO1 | -3365.0 | 57.0 |
| SCO2 | -3687.0 | 2948.0 |
| SDHA | 3626.5 | -1630.5 |
| SDHB | 3180.0 | 7355.0 |
| SDHC | -860.0 | 834.0 |
| SDHD | 6887.5 | 1213.5 |
| SURF1 | 2134.0 | 4131.0 |
| TACO1 | -3888.0 | 3315.0 |
| TIMMDC1 | -2651.0 | -2924.0 |
| TMEM126B | -6725.0 | 3713.0 |
| TRAP1 | -6124.0 | 2675.0 |
| UQCR10 | 6187.0 | 697.0 |
| UQCR11 | 5012.5 | -3179.5 |
| UQCRB | -410.0 | 8334.0 |
| UQCRC1 | 5627.0 | 1729.0 |
| UQCRC2 | 2236.0 | 6852.0 |
| UQCRFS1 | 3296.0 | -3981.0 |
| UQCRH | 5780.5 | -5189.5 |
| UQCRQ | 6271.0 | 7840.0 |
GSE9006_HEALTHY_VS_TYPE_2_DIABETES_PBMC_AT_DX_DN
| metric | value |
|---|---|
| setSize | 170 |
| pMANOVA | 4.3e-07 |
| p.adjustMANOVA | 1.99e-06 |
| s.dist | 0.259 |
| s.diabetes | -0.119 |
| s.mitoG | 0.23 |
| p.diabetes | 0.00742 |
| p.mitoG | 2.38e-07 |
| Gene | diabetes | mitoG |
|---|---|---|
| PNP | -7335.0 | 8459.0 |
| DHX15 | -6821.0 | 8710.0 |
| ADAMTS1 | -5452.0 | 8739.0 |
| VPS35 | -5441.0 | 8535.0 |
| SEC23B | -6433.0 | 7123.0 |
| RNFT1 | -7085.0 | 6460.0 |
| RLF | -6959.0 | 6399.0 |
| USP9X | -5668.0 | 7709.0 |
| PIK3CG | -5373.0 | 8065.0 |
| DIS3 | -6175.0 | 6931.0 |
| ST8SIA4 | -6249.0 | 6735.0 |
| SRR | -5380.0 | 7655.0 |
| AFTPH | -5292.0 | 7576.0 |
| ARPC2 | -4512.0 | 8767.0 |
| TPTE | -5920.5 | 6543.5 |
| CLTC | -4493.0 | 8248.0 |
| KLF7 | -4593.0 | 8044.0 |
| MRPS22 | -6062.0 | 5844.0 |
| PUM2 | -6583.0 | 5351.0 |
| TLR6 | -4778.0 | 7142.0 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| ABHD5 | 2617.0 | 5120.0 |
| ACSL1 | 318.0 | 3006.0 |
| ADAMTS1 | -5452.0 | 8739.0 |
| ADO | -1293.0 | 4866.0 |
| AFTPH | -5292.0 | 7576.0 |
| AGGF1 | -5856.5 | 4390.5 |
| ALOX5AP | -1117.0 | 7096.0 |
| ALX1 | -683.0 | -381.0 |
| ANAPC13 | -4345.0 | 4356.0 |
| ANKRD12 | 2891.0 | 7723.0 |
| AP3B1 | 3159.0 | 1998.0 |
| ARPC2 | -4512.0 | 8767.0 |
| ASH1L | 2351.0 | 7274.0 |
| ATG10 | -442.0 | 4655.0 |
| ATP6V1E1 | -704.0 | 8548.0 |
| B4GALT5 | -7316.0 | -2072.0 |
| BMX | 5552.0 | 4493.0 |
| BTG2 | 6071.0 | 6308.0 |
| C11orf49 | 4238.0 | -2413.0 |
| C3AR1 | -1253.0 | 7488.0 |
| CACNB2 | 5838.0 | -5134.0 |
| CAMK2A | -2272.0 | 4664.0 |
| CCL8 | 2963.0 | -1525.0 |
| CCNJL | -3880.0 | 1011.0 |
| CCR1 | -3507.0 | 4981.0 |
| CD53 | -3501.0 | 7525.0 |
| CDC123 | 1994.0 | 3040.0 |
| CDC40 | 1666.0 | 5218.0 |
| CDH10 | -5060.0 | -2946.0 |
| CDH17 | -1983.0 | -292.0 |
| CDKL3 | 3884.0 | 4697.0 |
| CEMIP | 6626.0 | 1672.0 |
| CHTOP | -4615.0 | -1316.0 |
| CLTC | -4493.0 | 8248.0 |
| COA3 | 1248.0 | 4406.0 |
| COCH | -2313.0 | 1069.0 |
| COG2 | 549.0 | 4121.0 |
| CRYBG1 | -6776.0 | 25.0 |
| CSTF1 | 3995.0 | 1240.0 |
| CYP4F12 | 7297.5 | 2796.5 |
| DHX15 | -6821.0 | 8710.0 |
| DHX32 | -759.0 | 5873.0 |
| DIS3 | -6175.0 | 6931.0 |
| DNMBP | 4678.0 | 6019.0 |
| EDN1 | -1177.0 | 7690.0 |
| EGR1 | 1105.0 | 4313.0 |
| EGR2 | -1617.0 | 4130.0 |
| EGR3 | -3140.0 | 2625.0 |
| EIPR1 | -1798.0 | 3065.0 |
| ELF1 | -3303.0 | 7541.0 |
| EMSY | -4472.0 | 2078.0 |
| F2RL1 | 7281.0 | 4283.0 |
| FABP7 | -2994.0 | -570.0 |
| FAM114A1 | 3334.0 | 8336.0 |
| FAS | 3093.0 | 7580.0 |
| FBXO9 | -3297.0 | -3812.0 |
| FOXC1 | 5241.0 | -2301.0 |
| FZD7 | 4413.0 | -2110.0 |
| GCNT1 | -6421.0 | -331.0 |
| GDAP2 | 1325.0 | 7455.0 |
| GFOD2 | 714.0 | -3471.0 |
| GIGYF2 | -6140.0 | -70.0 |
| GPR182 | 7524.0 | 5618.0 |
| GYPA | -4292.0 | 6256.0 |
| HINFP | 297.0 | 1595.0 |
| IL1B | -6242.0 | 3978.0 |
| KCNJ1 | -2062.0 | 3417.0 |
| KCNJ15 | -5752.0 | 2831.0 |
| KIAA0319 | 1289.0 | -5453.0 |
| KLF6 | 145.0 | 7678.0 |
| KLF7 | -4593.0 | 8044.0 |
| LIG4 | -3349.0 | 7573.0 |
| LIMK2 | 7085.0 | -848.0 |
| LMBRD1 | 4227.0 | 4468.0 |
| LPAR6 | -2000.0 | -461.0 |
| MACIR | -3913.0 | -2181.0 |
| MAFB | 8140.0 | 2473.0 |
| MAN2A1 | 8162.0 | 5453.0 |
| MCL1 | 6260.0 | -1020.0 |
| MFAP3 | 2866.0 | 4624.0 |
| MGAM | 561.0 | 417.0 |
| MKLN1 | 582.0 | 3529.0 |
| MON2 | -1660.0 | -2065.0 |
| MOSPD2 | -1998.0 | 8209.0 |
| MRPS22 | -6062.0 | 5844.0 |
| MTF1 | -4371.0 | -3922.0 |
| MTHFS | 179.5 | -3965.5 |
| MTO1 | -6215.0 | 1994.0 |
| MTOR | -4145.0 | -2344.0 |
| NAV2 | -3698.0 | -4133.0 |
| NDEL1 | 206.0 | 1834.0 |
| NOP10 | 2308.0 | 5890.0 |
| NSUN3 | 595.0 | 3091.0 |
| PAFAH1B1 | -3995.0 | 8266.0 |
| PCNX1 | 7739.0 | 781.0 |
| PDE8A | -3329.0 | 7592.0 |
| PEX3 | 453.0 | 6955.0 |
| PFKM | 5220.0 | -2428.0 |
| PIK3CG | -5373.0 | 8065.0 |
| PIK3R4 | 4272.0 | -1214.0 |
| PKNOX2 | 5475.0 | 3240.0 |
| PLIN2 | 3994.0 | 4652.0 |
| PNP | -7335.0 | 8459.0 |
| POGLUT1 | -1880.0 | 2758.0 |
| POLR2B | -675.0 | 5037.0 |
| PRDM4 | 4788.0 | 2144.0 |
| PROX1 | 7033.0 | -3710.0 |
| PSMA7 | 1612.0 | 7052.0 |
| PTGS2 | -2970.0 | 5783.0 |
| PTPN21 | 2719.0 | -4215.0 |
| PTRH2 | -3116.0 | 273.0 |
| PUM2 | -6583.0 | 5351.0 |
| PUS3 | -4535.0 | 6560.0 |
| RAB11FIP2 | 4139.0 | 931.0 |
| RAD17 | -430.0 | 6957.0 |
| RAE1 | 3041.0 | -1934.0 |
| RALGPS1 | 2494.0 | -5324.0 |
| RBM47 | 1021.0 | -1394.0 |
| RBMS1 | -4349.0 | 7009.0 |
| RBPJ | 2571.0 | 4528.0 |
| RGL1 | -6436.0 | -5685.0 |
| RGS2 | 3150.0 | 1108.0 |
| RHEB | -3280.0 | -1691.0 |
| RLF | -6959.0 | 6399.0 |
| RNF17 | -169.0 | 1065.0 |
| RNF34 | 48.0 | 4672.0 |
| RNFT1 | -7085.0 | 6460.0 |
| RPH3A | 6618.0 | -1014.0 |
| RPS6KA5 | 2516.0 | -3206.0 |
| RTCB | -1912.0 | -1661.0 |
| SCRN3 | -6919.0 | 2841.0 |
| SCYL3 | 5375.0 | 225.0 |
| SEC23B | -6433.0 | 7123.0 |
| SGK1 | 4488.0 | 7322.0 |
| SH2D3C | 6944.0 | 958.0 |
| SLC17A5 | 2333.0 | 243.0 |
| SON | -1196.0 | 3884.0 |
| SPARCL1 | 5687.0 | 8683.0 |
| SRR | -5380.0 | 7655.0 |
| ST8SIA4 | -6249.0 | 6735.0 |
| STRADA | 5090.0 | -5448.0 |
| STXBP5L | -7008.0 | -3600.0 |
| SUOX | 6862.0 | -1063.0 |
| TAX1BP1 | 3157.0 | 7948.0 |
| TLR1 | -3224.0 | 560.0 |
| TLR2 | 5407.0 | 5188.0 |
| TLR3 | 1181.0 | 6018.0 |
| TLR6 | -4778.0 | 7142.0 |
| TLR8 | 281.0 | 6768.0 |
| TNFAIP1 | -1850.0 | 8190.0 |
| TNFSF14 | -1855.0 | 436.0 |
| TP73 | 2068.0 | 84.0 |
| TPTE | -5920.5 | 6543.5 |
| TREML2 | -3185.0 | 3037.0 |
| TRIB1 | 7573.0 | 2586.0 |
| USP10 | -1816.0 | -1370.0 |
| USP9X | -5668.0 | 7709.0 |
| USPL1 | -6079.0 | 3330.0 |
| UTP25 | -910.0 | -3889.0 |
| UVRAG | -5823.0 | -64.0 |
| VNN1 | 6246.0 | 7250.0 |
| VPS13D | -414.0 | 3107.0 |
| VPS35 | -5441.0 | 8535.0 |
| WDFY3 | -6210.0 | -6585.0 |
| WIPF2 | 4034.0 | -1247.0 |
| XRCC4 | -4715.0 | 7026.0 |
| ZBTB24 | -5992.0 | -4128.0 |
| ZFYVE26 | -1775.0 | -6690.0 |
| ZKSCAN4 | -3447.0 | -5890.0 |
| ZNF654 | -1490.0 | 8187.0 |
KEGG_TYPE_I_DIABETES_MELLITUS
| metric | value |
|---|---|
| setSize | 25 |
| pMANOVA | 0.069 |
| p.adjustMANOVA | 0.109 |
| s.dist | 0.256 |
| s.diabetes | -0.255 |
| s.mitoG | -0.0245 |
| p.diabetes | 0.0274 |
| p.mitoG | 0.832 |
| Gene | diabetes | mitoG |
|---|---|---|
| HLA-DOB | -4577.0 | -4767.0 |
| HLA-DMB | -1643.5 | -3831.5 |
| PTPRN | -1366.0 | -4132.0 |
| PRF1 | -1422.0 | -684.0 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| CD28 | -4408.0 | 5134.0 |
| CD80 | -3453.0 | 3286.0 |
| CD86 | -2679.0 | 5554.0 |
| CPE | -7351.0 | 8370.0 |
| FAS | 3093.0 | 7580.0 |
| FASLG | 834.0 | 4880.0 |
| GAD1 | -2488.0 | 2186.0 |
| GZMB | 270.0 | -2421.0 |
| HLA-DMA | 275.0 | -5969.0 |
| HLA-DMB | -1643.5 | -3831.5 |
| HLA-DOA | -5599.0 | 3997.0 |
| HLA-DOB | -4577.0 | -4767.0 |
| HLA-DQB1 | -4730.5 | 1217.5 |
| HLA-DRB1 | 1762.5 | -4711.5 |
| HLA-DRB5 | 1762.5 | -4711.5 |
| HLA-E | 3698.5 | -6121.5 |
| HLA-G | 3698.5 | -6121.5 |
| HSPD1 | -7211.0 | 3739.0 |
| ICA1 | -2242.0 | 7076.0 |
| IL1A | -1142.0 | 1688.0 |
| IL1B | -6242.0 | 3978.0 |
| PRF1 | -1422.0 | -684.0 |
| PTPRN | -1366.0 | -4132.0 |
| PTPRN2 | 5657.0 | 877.0 |
| TNF | -2778.0 | 4883.0 |
HP_TYPE_I_DIABETES_MELLITUS
| metric | value |
|---|---|
| setSize | 38 |
| pMANOVA | 0.0116 |
| p.adjustMANOVA | 0.0269 |
| s.dist | 0.252 |
| s.diabetes | 0.117 |
| s.mitoG | 0.224 |
| p.diabetes | 0.212 |
| p.mitoG | 0.017 |
| Gene | diabetes | mitoG |
|---|---|---|
| EDA2R | 8226 | 6933 |
| MT-ND5 | 6025 | 8007 |
| MT-ND1 | 5618 | 7323 |
| MT-ND6 | 5059 | 8045 |
| MT-CO1 | 6781 | 5983 |
| EDA | 4324 | 6384 |
| MMP14 | 2752 | 7195 |
| TKT | 8181 | 2150 |
| TCF4 | 2008 | 7220 |
| MT-CO3 | 2273 | 6269 |
| MT-ND4 | 1752 | 7883 |
| MMP2 | 1375 | 7816 |
| KCTD1 | 339 | 4479 |
| DNAJC21 | 174 | 7090 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| AIRE | 2208.0 | -3619.0 |
| CAT | -602.0 | 4907.0 |
| CLCNKB | 8258.5 | -2053.5 |
| CNOT1 | -2585.0 | 3418.0 |
| CORIN | 3128.0 | -555.0 |
| DNAJC21 | 174.0 | 7090.0 |
| DNAJC3 | -7149.0 | 8179.0 |
| EDA | 4324.0 | 6384.0 |
| EDA2R | 8226.0 | 6933.0 |
| EFL1 | -3377.0 | 4737.0 |
| EIF2AK3 | -6386.0 | 3372.0 |
| FLT1 | -4346.0 | 8420.0 |
| FOXP3 | 2855.0 | -5240.0 |
| GPR35 | -2136.0 | 5566.0 |
| HNF1A | 7450.0 | -6675.0 |
| ITCH | -4378.0 | 5792.0 |
| KCTD1 | 339.0 | 4479.0 |
| MMP14 | 2752.0 | 7195.0 |
| MMP2 | 1375.0 | 7816.0 |
| MST1 | 4315.0 | -5473.0 |
| MT-CO1 | 6781.0 | 5983.0 |
| MT-CO2 | 293.0 | -1711.0 |
| MT-CO3 | 2273.0 | 6269.0 |
| MT-ND1 | 5618.0 | 7323.0 |
| MT-ND4 | 1752.0 | 7883.0 |
| MT-ND5 | 6025.0 | 8007.0 |
| MT-ND6 | 5059.0 | 8045.0 |
| PSTPIP1 | -1224.0 | -988.0 |
| SBDS | -2078.0 | 7401.0 |
| SLC12A3 | 6051.0 | -4654.0 |
| SLC16A2 | -6598.0 | -2679.0 |
| SRP54 | -4728.0 | 8835.0 |
| STAT1 | -3464.0 | -4440.0 |
| STOX1 | 396.0 | -1368.0 |
| STUB1 | 4177.0 | -2823.0 |
| TCF4 | 2008.0 | 7220.0 |
| TKT | 8181.0 | 2150.0 |
| TTC7A | 7100.0 | -5688.0 |
The citric acid (TCA) cycle and respiratory electron transport
| metric | value |
|---|---|
| setSize | 168 |
| pMANOVA | 1.1e-08 |
| p.adjustMANOVA | 8.16e-08 |
| s.dist | 0.241 |
| s.diabetes | 0.162 |
| s.mitoG | 0.178 |
| p.diabetes | 0.000288 |
| p.mitoG | 7.32e-05 |
| Gene | diabetes | mitoG |
|---|---|---|
| COX7B | 6102.0 | 8760.0 |
| ACO2 | 7295.0 | 7282.0 |
| ATP5PO | 6640.5 | 7456.5 |
| UQCRQ | 6271.0 | 7840.0 |
| MT-ND5 | 6025.0 | 8007.0 |
| ME2 | 6693.0 | 6628.0 |
| PDK1 | 8236.0 | 5206.0 |
| MT-ND1 | 5618.0 | 7323.0 |
| MT-ND6 | 5059.0 | 8045.0 |
| MT-CO1 | 6781.0 | 5983.0 |
| COX6B1 | 5091.0 | 7299.0 |
| NDUFA6 | 6990.0 | 5257.0 |
| NDUFA12 | 4539.0 | 8087.0 |
| NDUFV2 | 4127.0 | 8731.0 |
| NDUFB8 | 4901.5 | 6790.5 |
| PDP1 | 4298.0 | 7517.0 |
| UCP2 | 6987.0 | 4595.0 |
| ATP5PD | 5135.0 | 6133.0 |
| CS | 5645.0 | 5457.0 |
| NDUFA7 | 7477.5 | 4100.5 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| ACAD9 | -4848.0 | -2818.0 |
| ACO2 | 7295.0 | 7282.0 |
| ADHFE1 | -6733.0 | 240.0 |
| ATP5F1A | 6316.0 | 1471.0 |
| ATP5F1B | 1691.0 | 1750.0 |
| ATP5F1C | 164.0 | 8242.0 |
| ATP5F1D | 5225.0 | 673.0 |
| ATP5F1E | 6241.0 | -5774.0 |
| ATP5MC3 | 6278.0 | -5724.0 |
| ATP5ME | 3268.0 | 3202.0 |
| ATP5MF | 6860.0 | -1957.0 |
| ATP5MG | 5923.5 | 564.5 |
| ATP5PB | 1124.0 | 5544.0 |
| ATP5PD | 5135.0 | 6133.0 |
| ATP5PF | 710.0 | 7012.0 |
| ATP5PO | 6640.5 | 7456.5 |
| BSG | -3166.0 | 5032.0 |
| COQ10A | 7831.0 | -5063.0 |
| COQ10B | 219.0 | 7422.0 |
| COX11 | 742.0 | -1169.0 |
| COX14 | 2703.0 | -3376.0 |
| COX16 | -3433.0 | 7416.0 |
| COX18 | 5019.0 | 1575.0 |
| COX19 | -2099.0 | 3124.0 |
| COX20 | -4714.0 | 6792.0 |
| COX4I1 | 6324.0 | -2473.0 |
| COX5B | 7740.0 | -2295.0 |
| COX6A1 | 5658.0 | -2138.0 |
| COX6B1 | 5091.0 | 7299.0 |
| COX6C | 7537.0 | 1755.0 |
| COX7A2L | 4007.0 | 4780.0 |
| COX7B | 6102.0 | 8760.0 |
| COX7C | 4066.0 | -5285.0 |
| COX8A | 5622.0 | -4787.0 |
| CS | 5645.0 | 5457.0 |
| CYC1 | 7497.0 | -4809.0 |
| D2HGDH | -4629.0 | -6471.0 |
| DLAT | 3962.0 | 2209.0 |
| DLD | -2523.0 | 7607.0 |
| DLST | 6249.0 | 251.0 |
| DMAC2L | 1623.0 | -997.0 |
| ECSIT | -3596.0 | 1408.0 |
| ETFA | -4953.0 | 3129.0 |
| ETFB | 5896.0 | -2345.0 |
| ETFDH | -5320.0 | 8131.0 |
| FAHD1 | -5635.0 | 4647.0 |
| FH | 1716.0 | 7771.0 |
| GLO1 | -6305.0 | 1741.0 |
| GSTZ1 | -3082.0 | 5598.0 |
| HAGH | 1822.0 | 7296.0 |
| IDH2 | 155.0 | 1563.0 |
| IDH3A | -958.0 | 7080.0 |
| IDH3B | 3081.0 | 573.0 |
| IDH3G | -4880.0 | 6728.0 |
| L2HGDH | 1057.0 | -1650.0 |
| LDHA | -5897.0 | 843.0 |
| LDHAL6B | 2680.0 | -6086.0 |
| LDHB | 5412.5 | 4669.5 |
| LRPPRC | 3831.0 | 6319.0 |
| MDH2 | 3713.0 | 4456.0 |
| ME1 | -7337.0 | 4579.0 |
| ME2 | 6693.0 | 6628.0 |
| ME3 | 1300.0 | -1217.0 |
| MPC1 | -3373.0 | 8178.0 |
| MPC2 | 5946.0 | -6209.0 |
| MT-ATP6 | -5818.0 | 8744.0 |
| MT-ATP8 | 3277.0 | 6153.0 |
| MT-CO1 | 6781.0 | 5983.0 |
| MT-CO2 | 293.0 | -1711.0 |
| MT-CO3 | 2273.0 | 6269.0 |
| MT-CYB | 3577.0 | 8110.0 |
| MT-ND1 | 5618.0 | 7323.0 |
| MT-ND2 | -1693.0 | 8626.0 |
| MT-ND3 | 1835.0 | 8689.0 |
| MT-ND4 | 1752.0 | 7883.0 |
| MT-ND5 | 6025.0 | 8007.0 |
| MT-ND6 | 5059.0 | 8045.0 |
| NDUFA1 | 2104.0 | -4989.0 |
| NDUFA10 | -1891.0 | 7765.0 |
| NDUFA11 | 7279.5 | 474.5 |
| NDUFA12 | 4539.0 | 8087.0 |
| NDUFA13 | 4768.0 | -2346.0 |
| NDUFA2 | 5261.0 | -6155.0 |
| NDUFA3 | 4319.0 | 82.0 |
| NDUFA4 | -5102.0 | 8096.0 |
| NDUFA5 | 7846.0 | 2875.0 |
| NDUFA6 | 6990.0 | 5257.0 |
| NDUFA7 | 7477.5 | 4100.5 |
| NDUFA8 | 5308.0 | 4366.0 |
| NDUFA9 | 3756.0 | -5331.0 |
| NDUFAB1 | 251.0 | 2742.0 |
| NDUFAF1 | -5470.0 | 1013.0 |
| NDUFAF2 | -2453.0 | 6013.0 |
| NDUFAF3 | -983.0 | -2862.0 |
| NDUFAF4 | -5532.0 | 7346.0 |
| NDUFAF5 | 1712.0 | 1907.0 |
| NDUFAF6 | -2110.0 | -2934.0 |
| NDUFAF7 | 1694.0 | 6697.0 |
| NDUFB1 | 5672.0 | 711.0 |
| NDUFB10 | 4853.0 | -1340.0 |
| NDUFB11 | 1539.0 | 7247.0 |
| NDUFB2 | 2034.0 | -5126.0 |
| NDUFB3 | -2553.0 | -4632.0 |
| NDUFB4 | -5247.0 | 8719.0 |
| NDUFB5 | 450.0 | 2312.0 |
| NDUFB6 | 6783.0 | 848.0 |
| NDUFB7 | 5336.0 | 2347.0 |
| NDUFB8 | 4901.5 | 6790.5 |
| NDUFB9 | 6765.0 | 1224.0 |
| NDUFC1 | 1620.0 | 3968.0 |
| NDUFC2 | 4564.5 | -5546.5 |
| NDUFS1 | -1094.0 | 6402.0 |
| NDUFS2 | 1841.0 | 4991.0 |
| NDUFS3 | 4184.0 | -2145.0 |
| NDUFS4 | 4791.0 | 4043.0 |
| NDUFS5 | 5126.0 | -4249.0 |
| NDUFS6 | 2287.0 | 6500.0 |
| NDUFS7 | 7367.0 | -5947.0 |
| NDUFS8 | 1961.0 | 2910.0 |
| NDUFV1 | 4313.0 | -2431.0 |
| NDUFV2 | 4127.0 | 8731.0 |
| NDUFV3 | -5257.0 | 5625.0 |
| NNT | 4576.0 | 4716.0 |
| NUBPL | -1636.0 | -1999.0 |
| OGDH | 6393.0 | 3583.0 |
| PDHA1 | -16.0 | 7978.0 |
| PDHB | 182.0 | 8175.0 |
| PDHX | -1471.0 | 7544.0 |
| PDK1 | 8236.0 | 5206.0 |
| PDK2 | 8043.0 | -1425.0 |
| PDK3 | -7135.0 | 6177.0 |
| PDK4 | 3864.0 | 4092.0 |
| PDP1 | 4298.0 | 7517.0 |
| PDP2 | -1525.0 | -1465.0 |
| PDPR | -1560.0 | -1589.0 |
| PM20D1 | -4304.0 | -1376.0 |
| PPARD | -6955.0 | -1980.0 |
| RXRA | -5143.0 | 1552.0 |
| SCO1 | -3365.0 | 57.0 |
| SCO2 | -3687.0 | 2948.0 |
| SDHA | 3626.5 | -1630.5 |
| SDHB | 3180.0 | 7355.0 |
| SDHC | -860.0 | 834.0 |
| SDHD | 6887.5 | 1213.5 |
| SLC16A1 | -7027.0 | 5763.0 |
| SLC16A3 | 5619.0 | -3522.0 |
| SLC16A8 | 87.0 | -4934.0 |
| SLC25A14 | -1689.0 | -3486.0 |
| SLC25A27 | 1702.0 | -2334.0 |
| SUCLA2 | -5284.0 | 8723.0 |
| SUCLG1 | 1641.0 | 7641.0 |
| SUCLG2 | 2515.0 | 3596.0 |
| SURF1 | 2134.0 | 4131.0 |
| TACO1 | -3888.0 | 3315.0 |
| TIMMDC1 | -2651.0 | -2924.0 |
| TMEM126B | -6725.0 | 3713.0 |
| TRAP1 | -6124.0 | 2675.0 |
| UCP2 | 6987.0 | 4595.0 |
| UCP3 | 3545.0 | -4364.0 |
| UQCR10 | 6187.0 | 697.0 |
| UQCR11 | 5012.5 | -3179.5 |
| UQCRB | -410.0 | 8334.0 |
| UQCRC1 | 5627.0 | 1729.0 |
| UQCRC2 | 2236.0 | 6852.0 |
| UQCRFS1 | 3296.0 | -3981.0 |
| UQCRH | 5780.5 | -5189.5 |
| UQCRQ | 6271.0 | 7840.0 |
| VDAC1 | 6.0 | 6549.0 |
HP_NEONATAL_INSULIN_DEPENDENT_DIABETES_MELLITUS
| metric | value |
|---|---|
| setSize | 10 |
| pMANOVA | 0.338 |
| p.adjustMANOVA | 0.447 |
| s.dist | 0.239 |
| s.diabetes | 0.166 |
| s.mitoG | 0.172 |
| p.diabetes | 0.364 |
| p.mitoG | 0.347 |
| Gene | diabetes | mitoG |
|---|---|---|
| STAT3 | 8126 | 4982 |
| PLAGL1 | 6416 | 5973 |
| KLF11 | 7284 | 1719 |
| APPL1 | 940 | 7089 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| APPL1 | 940 | 7089 |
| EIF2AK3 | -6386 | 3372 |
| GATA6 | -1651 | 6694 |
| HNF1A | 7450 | -6675 |
| HNF4A | -6855 | 4619 |
| KCNJ11 | 2961 | -3265 |
| KLF11 | 7284 | 1719 |
| PLAGL1 | 6416 | 5973 |
| STAT3 | 8126 | 4982 |
| ZFP57 | -749 | -781 |
GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_4MONTH_POST_DX_UP
| metric | value |
|---|---|
| setSize | 193 |
| pMANOVA | 1.45e-07 |
| p.adjustMANOVA | 7.66e-07 |
| s.dist | 0.231 |
| s.diabetes | -0.00752 |
| s.mitoG | 0.231 |
| p.diabetes | 0.857 |
| p.mitoG | 3.4e-08 |
| Gene | diabetes | mitoG |
|---|---|---|
| PTGES3 | -7067 | 8733 |
| HNRNPA3 | -6985 | 8827 |
| PDIA3 | -7283 | 7821 |
| SUMO3 | -7259 | 7825 |
| PDIA4 | -7329 | 7729 |
| RPN1 | -7121 | 7464 |
| RNF11 | -7128 | 7320 |
| LYPLA1 | -6790 | 7638 |
| QKI | -6268 | 8165 |
| TWF1 | -6517 | 7512 |
| ATF4 | -6143 | 7857 |
| PTEN | -5726 | 8365 |
| YWHAZ | -5614 | 8512 |
| BTBD1 | -5007 | 8727 |
| DDX21 | -5116 | 8276 |
| SEC63 | -4922 | 8290 |
| PPP1CB | -4617 | 8661 |
| ACTR2 | -5189 | 7356 |
| HNRNPU | -5219 | 7082 |
| PAK2 | -4906 | 6708 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| AAMP | 69.0 | -4287.0 |
| AATF | 2607.0 | 2827.0 |
| ACTG1 | -1502.0 | 1482.0 |
| ACTR2 | -5189.0 | 7356.0 |
| ADAM9 | -5133.0 | 6361.0 |
| ADNP2 | 2146.0 | 595.0 |
| AGPS | -7336.0 | 594.0 |
| AHCY | -3362.0 | -6342.0 |
| AKIRIN1 | -211.0 | 8518.0 |
| ALDOA | 6979.5 | 3652.5 |
| ANXA5 | 350.0 | 5743.0 |
| ARHGAP26 | -7093.0 | 2682.0 |
| ATF3 | -845.0 | 6400.0 |
| ATF4 | -6143.0 | 7857.0 |
| ATMIN | 3967.0 | -1041.0 |
| ATP1B3 | -1025.0 | 8436.0 |
| AZIN1 | 6036.0 | 4792.0 |
| BHLHE40 | -185.0 | 1804.0 |
| BNIP2 | 3400.0 | 6267.0 |
| BTBD1 | -5007.0 | 8727.0 |
| C8orf33 | 5060.0 | -3701.0 |
| CARF | 1056.0 | -3624.0 |
| CD69 | -4208.0 | 443.0 |
| CHFR | 686.0 | 5588.0 |
| CIRBP | 8197.0 | -922.0 |
| CKAP4 | 4629.0 | 6520.0 |
| CLP1 | 4455.0 | -5275.0 |
| COPA | 488.0 | 2943.0 |
| COPS7B | -2394.0 | -5916.0 |
| COTL1 | 8183.0 | -5409.0 |
| CPNE3 | 1709.0 | 7633.0 |
| CPSF6 | -4618.0 | 2233.0 |
| CREM | -3568.0 | 7564.0 |
| CTSB | 7086.0 | -1439.0 |
| CXCR4 | 4516.0 | 7547.0 |
| CYBB | -5520.0 | 5307.0 |
| DAZAP2 | 5976.0 | 2413.0 |
| DDIT4 | 5684.0 | 4879.0 |
| DDX21 | -5116.0 | 8276.0 |
| DDX3X | 3775.0 | 8058.0 |
| DNAJA2 | -3327.0 | 8515.0 |
| DOCK2 | -5657.0 | 5085.0 |
| DPYSL2 | 1058.0 | 7621.0 |
| DUSP10 | 4557.0 | 5745.0 |
| DUSP5 | 4923.0 | 4971.0 |
| DUT | 1159.0 | 688.0 |
| ECPAS | 2810.0 | 6759.0 |
| ECSIT | -3596.0 | 1408.0 |
| EIF4G3 | -7083.0 | 1872.0 |
| EIF4H | 5370.0 | -98.0 |
| EPS15 | -5197.0 | 5904.0 |
| FAM53C | -5211.0 | -2385.0 |
| FEM1B | -180.0 | 4328.0 |
| FLI1 | -110.0 | 7996.0 |
| G0S2 | 4904.0 | 8051.0 |
| G3BP2 | -4462.0 | 5928.0 |
| GADD45B | 7485.0 | 1360.0 |
| GLUD1 | 8064.5 | 3730.5 |
| GLUD2 | 8064.5 | 3730.5 |
| GLUL | 7900.0 | 3064.0 |
| GNAI3 | -3916.0 | 8277.0 |
| GPI | 4816.0 | 5422.0 |
| HADHA | 6883.0 | 5617.0 |
| HAUS3 | -3198.0 | 5697.0 |
| HIF1A | 7374.0 | 8562.0 |
| HMGB1 | 2876.0 | 8283.0 |
| HNRNPA1 | 7891.0 | -6290.0 |
| HNRNPA3 | -6985.0 | 8827.0 |
| HNRNPD | 6599.0 | 1068.0 |
| HNRNPH2 | -5391.0 | 5932.0 |
| HNRNPM | -6548.0 | -2929.0 |
| HNRNPU | -5219.0 | 7082.0 |
| HSPA9 | -566.0 | 8181.0 |
| IER5 | 5330.0 | 2127.0 |
| ILKAP | -3346.0 | -3704.0 |
| ILVBL | 3004.0 | -6442.0 |
| IRF1 | 3086.0 | 3498.0 |
| JUN | 581.0 | 5314.0 |
| JUNB | 4544.0 | 2430.0 |
| KIAA0930 | 4163.0 | -2258.0 |
| KLF10 | 3691.0 | 2691.0 |
| KLF11 | 7284.0 | 1719.0 |
| KLF9 | 3425.0 | 3735.0 |
| KPNB1 | -1668.0 | 5829.0 |
| LAP3 | -7119.0 | 4235.0 |
| LAPTM5 | -5721.0 | 4643.0 |
| LSM12 | -2869.0 | 4929.0 |
| LYPLA1 | -6790.0 | 7638.0 |
| MAFF | 4078.0 | 3523.0 |
| MAPK1IP1L | 345.0 | -2618.0 |
| MAPRE1 | -3633.0 | 8509.0 |
| MARCKS | -1781.0 | 5038.0 |
| MBD2 | -1599.0 | 7442.0 |
| MFSD1 | -2465.0 | -4309.0 |
| MKRN1 | -6560.0 | 3886.0 |
| MSN | -1294.0 | 5246.0 |
| MTMR12 | -4933.0 | 6552.0 |
| MVP | 6785.0 | -5147.0 |
| NADSYN1 | 6875.0 | -6478.0 |
| NAPG | 3323.0 | 2180.0 |
| NDUFV1 | 4313.0 | -2431.0 |
| NFKB2 | 2120.0 | -4751.0 |
| NFKBIA | 1631.0 | 4830.0 |
| NFKBIE | -4334.0 | -123.0 |
| NKAPD1 | -880.0 | 7075.0 |
| NPTN | 2459.0 | 6839.0 |
| NR4A2 | -168.0 | 5972.0 |
| NRIP1 | -4907.0 | 6136.0 |
| NUP93 | 5331.0 | 6196.0 |
| ODF2 | 8196.0 | -5679.0 |
| OLA1 | -105.0 | 6435.0 |
| OSTF1 | 6553.0 | 5854.0 |
| PABPC1 | -949.0 | 6861.0 |
| PABPC4 | 2846.0 | -3784.0 |
| PAK2 | -4906.0 | 6708.0 |
| PCBP2 | 6135.0 | 1313.0 |
| PDIA3 | -7283.0 | 7821.0 |
| PDIA4 | -7329.0 | 7729.0 |
| PIGA | 5537.0 | -3293.0 |
| PIGT | 2201.0 | -3364.0 |
| PIK3R1 | -839.0 | 8363.0 |
| PKN1 | 4322.0 | -4516.0 |
| PLIN3 | 5004.0 | -4323.0 |
| PPFIA1 | 3451.0 | -2521.0 |
| PPP1CB | -4617.0 | 8661.0 |
| PPP2R5E | 5001.0 | 2898.0 |
| PRMT7 | 5794.0 | 1791.0 |
| PSMD2 | -6702.0 | -3836.0 |
| PTEN | -5726.0 | 8365.0 |
| PTGES3 | -7067.0 | 8733.0 |
| PTP4A1 | 6088.0 | 8315.0 |
| QKI | -6268.0 | 8165.0 |
| RAB5B | 5887.0 | 3206.0 |
| RAP2C | -4441.0 | 2874.0 |
| RBM3 | 8175.0 | 5192.0 |
| REEP4 | 3119.0 | -2877.0 |
| RETREG2 | -3830.0 | -5500.0 |
| RIOK3 | -3202.0 | 8097.0 |
| RNASEH1 | 2749.5 | -5225.5 |
| RNF11 | -7128.0 | 7320.0 |
| RNF19B | -3119.0 | -1959.0 |
| RNF38 | 2503.0 | -1772.0 |
| RPN1 | -7121.0 | 7464.0 |
| RRAGD | 7798.0 | 3815.0 |
| RTN3 | -2760.0 | 5623.0 |
| SAFB | -1933.0 | -1132.0 |
| SAFB2 | 3321.0 | -6673.0 |
| SART1 | 2632.0 | -1920.0 |
| SCO2 | -3687.0 | 2948.0 |
| SCPEP1 | 4057.0 | 1287.0 |
| SEC31A | 835.0 | -552.0 |
| SEC63 | -4922.0 | 8290.0 |
| SF3A1 | -4724.0 | -831.0 |
| SFN | 3916.0 | 5704.0 |
| SFPQ | -5196.0 | -4828.0 |
| SIK1 | 3616.5 | 666.5 |
| SIL1 | -5762.0 | 4185.0 |
| SNF8 | 2397.0 | -3270.0 |
| SNX6 | -7210.0 | 1661.0 |
| SPCS3 | 4330.0 | 1501.0 |
| SRRM1 | 5551.0 | 7062.0 |
| SRSF9 | -2009.0 | -5029.0 |
| STK17B | -265.0 | 7680.0 |
| STRAP | 1715.0 | 7369.0 |
| SUCLG2 | 2515.0 | 3596.0 |
| SUMO3 | -7259.0 | 7825.0 |
| TAOK3 | 2465.0 | -3763.0 |
| TAP2 | 5211.5 | -5555.5 |
| TERF2IP | -2169.0 | 2046.0 |
| TESK2 | 2566.0 | -4280.0 |
| TMED2 | -2351.0 | 6953.0 |
| TNFAIP3 | -151.0 | 2986.0 |
| TOB1 | 1023.0 | 6857.0 |
| TOM1 | -2514.0 | -174.0 |
| TOR3A | 6590.0 | 6359.0 |
| TPD52L2 | 95.0 | 3488.0 |
| TPST2 | 5077.0 | -171.0 |
| TSC22D3 | 1663.0 | 5520.0 |
| TSR3 | 4228.0 | -5856.0 |
| TWF1 | -6517.0 | 7512.0 |
| TYMP | 5612.0 | -6441.0 |
| UAP1 | -7245.0 | 1255.0 |
| UBAC1 | 6069.0 | -2026.0 |
| UQCRC1 | 5627.0 | 1729.0 |
| USP7 | -4172.0 | 7828.0 |
| VDAC1 | 6.0 | 6549.0 |
| WTAP | -3354.0 | 6889.0 |
| XRCC6 | -1971.0 | 4034.0 |
| YBX3 | 5916.0 | 4090.0 |
| YPEL5 | 8001.0 | 3939.0 |
| YWHAZ | -5614.0 | 8512.0 |
| ZNF394 | 73.0 | -278.0 |
| ZNF551 | -3852.0 | 2620.0 |
BAELDE_DIABETIC_NEPHROPATHY_UP
| metric | value |
|---|---|
| setSize | 78 |
| pMANOVA | 0.000725 |
| p.adjustMANOVA | 0.00224 |
| s.dist | 0.226 |
| s.diabetes | 0.205 |
| s.mitoG | 0.0948 |
| p.diabetes | 0.00175 |
| p.mitoG | 0.148 |
| Gene | diabetes | mitoG |
|---|---|---|
| CD34 | 7928.0 | 8147.0 |
| ENO1 | 8244.0 | 7737.0 |
| ENG | 7600.0 | 8006.0 |
| MT2A | 8239.0 | 7031.0 |
| PTGIS | 7164.0 | 6579.0 |
| MT1G | 8262.0 | 5621.0 |
| ZCCHC24 | 5250.0 | 8591.0 |
| CLU | 7398.0 | 5822.0 |
| PTPRM | 5478.0 | 7560.0 |
| BBOX1 | 6577.0 | 5810.0 |
| UNC5B | 6777.0 | 5303.0 |
| PECAM1 | 3970.0 | 8677.0 |
| ADGRF5 | 4138.0 | 8117.0 |
| PTPRB | 3085.0 | 8717.0 |
| FBP1 | 7186.0 | 2802.0 |
| CRIP1 | 2892.5 | 6423.5 |
| FAM53B | 6631.0 | 2759.0 |
| EML1 | 4749.0 | 3688.0 |
| SLCO2A1 | 7840.0 | 2219.0 |
| HYAL1 | 5242.0 | 3316.0 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| AANAT | -796.0 | 2183.0 |
| ACSM2A | -7294.5 | 1878.5 |
| ACVRL1 | -2455.0 | 7663.0 |
| ACY1 | -1207.5 | -4016.5 |
| ADAMTSL2 | 1075.0 | 7367.0 |
| ADGRF5 | 4138.0 | 8117.0 |
| ADGRG1 | 7358.0 | 493.0 |
| AKR1A1 | 816.0 | 1669.0 |
| ALDH4A1 | 3213.0 | -5888.0 |
| AOC1 | 5592.0 | -5405.0 |
| AQP1 | 6588.5 | -2440.5 |
| ARHGEF15 | 2583.0 | 849.0 |
| ASS1 | -6686.0 | -610.0 |
| ATP10B | -2699.0 | 3600.0 |
| BAX | 6141.0 | -6683.0 |
| BBOX1 | 6577.0 | 5810.0 |
| BPHL | -6521.0 | -4387.0 |
| C4A | -311.5 | -5183.5 |
| CAPN3 | 3009.0 | -6323.0 |
| CCDC69 | 3036.0 | -2502.0 |
| CCND1 | 7933.0 | -1628.0 |
| CD34 | 7928.0 | 8147.0 |
| CLU | 7398.0 | 5822.0 |
| CRIP1 | 2892.5 | 6423.5 |
| CTSH | -6661.0 | 6547.0 |
| CYP4F2 | 6042.0 | 596.0 |
| DPEP1 | 1301.0 | 5412.0 |
| EML1 | 4749.0 | 3688.0 |
| ENG | 7600.0 | 8006.0 |
| ENO1 | 8244.0 | 7737.0 |
| FAM53B | 6631.0 | 2759.0 |
| FBP1 | 7186.0 | 2802.0 |
| FTL | -6693.0 | -6771.0 |
| FXYD2 | -3344.5 | 4429.5 |
| GAS2L1 | -5204.0 | -3783.0 |
| GAS6 | 7430.0 | -2362.0 |
| GDPD5 | 7592.0 | 424.0 |
| GGT1 | -7165.0 | -1432.0 |
| GPLD1 | 1497.0 | -753.0 |
| HLA-DRB1 | 1762.5 | -4711.5 |
| HPN | -2955.0 | -6509.0 |
| HYAL1 | 5242.0 | 3316.0 |
| HYAL2 | -2781.0 | -4258.0 |
| ICAM2 | -3483.0 | 7311.0 |
| ID1 | 3953.0 | -1529.0 |
| IGFBP5 | -3193.0 | 3366.0 |
| IMPA2 | 7206.0 | -2131.0 |
| INPP5K | 8149.0 | -2011.0 |
| ITFG2 | 826.0 | -4600.0 |
| ITM2A | -2572.0 | 4825.0 |
| JADE3 | 2356.0 | 7037.0 |
| MAP4 | 1438.0 | 8670.0 |
| MIA2 | -5486.0 | 8570.0 |
| MT1G | 8262.0 | 5621.0 |
| MT2A | 8239.0 | 7031.0 |
| MT3 | -369.0 | -3432.0 |
| MYC | 1892.0 | 3123.0 |
| PDE2A | 3006.0 | 4319.0 |
| PECAM1 | 3970.0 | 8677.0 |
| PLPP3 | -2151.0 | 8260.0 |
| PPM1F | -571.0 | 446.0 |
| PTGIS | 7164.0 | 6579.0 |
| PTPRB | 3085.0 | 8717.0 |
| PTPRM | 5478.0 | 7560.0 |
| RAMP2 | 4827.0 | -1533.0 |
| RBPMS | 5172.0 | 810.0 |
| SEMA6A | -6678.0 | 6683.0 |
| SLC22A6 | -3170.0 | -395.0 |
| SLCO2A1 | 7840.0 | 2219.0 |
| SPG7 | 770.0 | -5074.0 |
| STARD8 | 3814.0 | 4312.0 |
| TEK | -2265.0 | 8575.0 |
| TIE1 | -1857.0 | 8467.0 |
| TLE2 | -2153.0 | -6181.0 |
| UGT1A10 | 8268.5 | -6174.5 |
| UNC5B | 6777.0 | 5303.0 |
| VAT1 | 7581.0 | -4263.0 |
| ZCCHC24 | 5250.0 | 8591.0 |
KEGG_MATURITY_ONSET_DIABETES_OF_THE_YOUNG
| metric | value |
|---|---|
| setSize | 13 |
| pMANOVA | 0.435 |
| p.adjustMANOVA | 0.537 |
| s.dist | 0.22 |
| s.diabetes | 0.0887 |
| s.mitoG | -0.201 |
| p.diabetes | 0.58 |
| p.mitoG | 0.209 |
| Gene | diabetes | mitoG |
|---|---|---|
| HNF1A | 7450 | -6675 |
| FOXA3 | 6771 | -2393 |
| NKX6-1 | 1836 | -2277 |
| PKLR | 8195 | -127 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| BHLHA15 | -853 | -1895 |
| FOXA3 | 6771 | -2393 |
| HES1 | 7353 | 4261 |
| HNF1A | 7450 | -6675 |
| HNF1B | -1771 | -6141 |
| HNF4A | -6855 | 4619 |
| HNF4G | -6407 | -1223 |
| MAFA | -3053 | 2846 |
| NKX6-1 | 1836 | -2277 |
| NR5A2 | -2631 | -1601 |
| PAX6 | -2974 | 1272 |
| PKLR | 8195 | -127 |
| SLC2A2 | 7902 | 2301 |
GSE9006_TYPE_1_VS_TYPE_2_DIABETES_PBMC_AT_DX_UP
| metric | value |
|---|---|
| setSize | 195 |
| pMANOVA | 0.00103 |
| p.adjustMANOVA | 0.00294 |
| s.dist | 0.158 |
| s.diabetes | 0.0321 |
| s.mitoG | -0.154 |
| p.diabetes | 0.44 |
| p.mitoG | 0.000208 |
| Gene | diabetes | mitoG |
|---|---|---|
| CCDC85B | 7941 | -6322 |
| FUS | 8128 | -5908 |
| ZNF512B | 7028 | -6394 |
| NADSYN1 | 6875 | -6478 |
| CCS | 6336 | -6627 |
| SNRPF | 6058 | -6379 |
| ABHD17A | 6198 | -5972 |
| PGLS | 7748 | -4404 |
| MFSD10 | 6323 | -5202 |
| MED22 | 6145 | -4961 |
| PEX5 | 4872 | -5747 |
| DCAF15 | 5603 | -4536 |
| POLR2E | 7128 | -3504 |
| TSR3 | 4228 | -5856 |
| AP5Z1 | 3582 | -6569 |
| SAFB2 | 3321 | -6673 |
| DAZAP1 | 5026 | -4228 |
| SAC3D1 | 4799 | -4190 |
| VPS51 | 3048 | -6458 |
| SNRNP70 | 2850 | -6750 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| AAMP | 69.0 | -4287.0 |
| ABCF3 | -1985.0 | -3254.0 |
| ABHD17A | 6198.0 | -5972.0 |
| ADRM1 | -6170.0 | -477.0 |
| AEBP1 | 7071.0 | 6822.0 |
| AIP | -549.0 | 3479.0 |
| AMBRA1 | 51.0 | -5388.0 |
| ANAPC2 | -3336.0 | -4659.0 |
| ANTKMT | 948.0 | -6642.0 |
| ANXA6 | 2396.0 | 7859.0 |
| AP5Z1 | 3582.0 | -6569.0 |
| APBA3 | -4271.0 | -3239.0 |
| ARF5 | 5403.0 | 222.0 |
| ARHGAP17 | -5151.0 | -4644.0 |
| ARHGAP4 | 2976.0 | -5989.0 |
| ARHGEF1 | 3750.0 | -3695.0 |
| ARPC4 | 3077.0 | 1525.0 |
| ATP13A1 | -1809.0 | -4057.0 |
| ATP1A1 | 8085.0 | 4179.0 |
| ATP2A3 | 6309.0 | 8551.0 |
| ATP5F1D | 5225.0 | 673.0 |
| AURKAIP1 | 4765.0 | 3868.0 |
| BANF1 | 3561.0 | -458.0 |
| BRMS1 | 1673.0 | 7971.0 |
| C9orf16 | 4926.0 | 854.0 |
| CCDC22 | -4166.0 | -3221.0 |
| CCDC85B | 7941.0 | -6322.0 |
| CCS | 6336.0 | -6627.0 |
| CD3E | -1202.0 | 619.0 |
| CD7 | -4515.0 | 2044.0 |
| CD81 | 3188.0 | 6614.0 |
| CDC37 | -682.0 | -4414.0 |
| CDCA4 | 4122.0 | 2492.0 |
| CDK2AP2 | -6964.0 | 359.0 |
| CDK9 | 315.0 | -5322.0 |
| CFDP1 | -4681.0 | 7182.0 |
| CFL1 | -1720.0 | 8321.0 |
| CLPTM1 | -4205.0 | 3839.0 |
| CNN2 | -2669.0 | 6553.0 |
| CNOT3 | 1322.0 | -5732.0 |
| COPG1 | -3891.0 | 3599.0 |
| COPS7B | -2394.0 | -5916.0 |
| CORO1A | -3183.0 | -17.0 |
| DAZAP1 | 5026.0 | -4228.0 |
| DCAF15 | 5603.0 | -4536.0 |
| DGKZ | -6561.0 | -2123.0 |
| DNAJC17 | 2361.0 | 3774.0 |
| DNAJC7 | -426.0 | 397.0 |
| DRAP1 | 5968.0 | 6776.0 |
| E4F1 | -2515.0 | -4079.0 |
| EDF1 | 2958.0 | -483.0 |
| EEF1D | -4117.0 | 717.0 |
| ERH | -4330.0 | 2173.0 |
| ERP29 | -6677.0 | -3655.0 |
| EXOC7 | 2029.0 | 3647.0 |
| FABP5 | 3630.0 | 2188.0 |
| FOXK2 | -5706.0 | 1999.0 |
| FUS | 8128.0 | -5908.0 |
| GADD45GIP1 | -3733.0 | 2788.0 |
| GATAD2A | -190.0 | 5669.0 |
| GCDH | 1309.0 | -1075.0 |
| GPS2 | 1228.0 | 2826.0 |
| GSN | 7535.0 | 7997.0 |
| GTF2H4 | 3818.0 | -4105.0 |
| GZMM | 1140.0 | -3497.0 |
| H2AX | 2476.0 | -807.0 |
| HDHD5 | -3358.0 | -6358.0 |
| HMG20B | 6566.0 | -1264.0 |
| HNRNPA2B1 | -2132.0 | -151.0 |
| HNRNPK | -808.0 | 7246.0 |
| HNRNPM | -6548.0 | -2929.0 |
| HRAS | 1503.0 | -318.0 |
| HSPA9 | -566.0 | 8181.0 |
| HTRA2 | 3076.0 | -6091.0 |
| ILKAP | -3346.0 | -3704.0 |
| IMPDH2 | 4946.0 | 4658.0 |
| IRF3 | 806.0 | -4184.0 |
| ITPKB | 4042.0 | 6200.0 |
| KLF13 | 8141.0 | -719.0 |
| LIMD2 | 2317.0 | 1635.0 |
| LPCAT4 | 3374.0 | 1637.0 |
| LRRC41 | 907.0 | -3596.0 |
| LSM12 | -2869.0 | 4929.0 |
| LSM14A | -4311.0 | 7661.0 |
| MARCKSL1 | -107.0 | 7707.0 |
| MED22 | 6145.0 | -4961.0 |
| MFSD10 | 6323.0 | -5202.0 |
| MRPL12 | -2913.0 | 4144.0 |
| MRPS2 | -5787.0 | 3563.0 |
| MTA1 | -1428.0 | -2770.0 |
| MZB1 | 2359.0 | -2500.0 |
| NAA60 | -1707.0 | 521.0 |
| NADSYN1 | 6875.0 | -6478.0 |
| NDUFC1 | 1620.0 | 3968.0 |
| NELFB | -4499.0 | -5790.0 |
| NFKBIB | 3850.0 | 467.0 |
| NOC2L | -4670.0 | 1010.0 |
| NONO | -5056.0 | 5895.0 |
| OSBPL2 | 388.0 | 6106.0 |
| PAF1 | 799.0 | 4723.0 |
| PDAP1 | 3245.0 | 700.0 |
| PDIA3 | -7283.0 | 7821.0 |
| PDIA4 | -7329.0 | 7729.0 |
| PDLIM2 | 6653.0 | 4632.0 |
| PEF1 | 536.0 | 294.0 |
| PEX5 | 4872.0 | -5747.0 |
| PFDN2 | -1073.0 | 7198.0 |
| PFDN6 | 2162.0 | -2593.0 |
| PFN1 | -3462.0 | -4129.0 |
| PGLS | 7748.0 | -4404.0 |
| PIN1 | 1926.0 | -1497.0 |
| POLD2 | 7422.0 | 3041.0 |
| POLR2E | 7128.0 | -3504.0 |
| PPIB | 2973.0 | 133.0 |
| PPP6R2 | 6009.0 | -1355.0 |
| PRCC | -3064.0 | -3244.0 |
| PRPF19 | 628.0 | 2226.0 |
| PRPF31 | -387.0 | 4117.0 |
| PRR5 | -6098.0 | -5369.0 |
| PSMB10 | 3752.0 | -908.0 |
| PTBP1 | -4264.0 | -2729.0 |
| PTMA | -3664.0 | 8371.0 |
| PTPN6 | -1098.0 | 2140.0 |
| PTPRCAP | -2234.0 | -289.0 |
| PUF60 | -754.0 | 731.0 |
| QTRT1 | 3026.0 | -4577.0 |
| RAB1B | -80.0 | -4574.0 |
| RALGDS | -3350.5 | -786.5 |
| RALY | -4431.0 | 5639.0 |
| RASGRP2 | -326.0 | -409.0 |
| RBM42 | -841.0 | -4924.0 |
| RPL11 | 5748.0 | 1403.0 |
| RPL36 | 7543.0 | -2424.0 |
| RPL37 | 2109.0 | -667.0 |
| RPLP2 | 3550.0 | 3555.0 |
| RRS1 | 3598.0 | 556.0 |
| RWDD1 | -3923.0 | 7824.0 |
| SAC3D1 | 4799.0 | -4190.0 |
| SAFB | -1933.0 | -1132.0 |
| SAFB2 | 3321.0 | -6673.0 |
| SART1 | 2632.0 | -1920.0 |
| SDF2L1 | -7228.0 | 2132.0 |
| SF3A2 | 1864.0 | -5244.0 |
| SF3B4 | 2644.0 | -4321.0 |
| SH3GLB2 | 284.0 | -2915.0 |
| SIGIRR | -826.0 | -4627.0 |
| SIPA1 | -3901.0 | 3867.0 |
| SLC25A22 | -2818.0 | 4428.0 |
| SLC39A4 | 4241.0 | -90.0 |
| SLC7A5 | 6666.0 | -84.0 |
| SMARCD2 | -3787.0 | 113.0 |
| SNF8 | 2397.0 | -3270.0 |
| SNRNP70 | 2850.0 | -6750.0 |
| SNRPF | 6058.0 | -6379.0 |
| SPINT2 | -1473.0 | -4181.0 |
| SREBF1 | -2758.0 | -4433.0 |
| SRRM1 | 5551.0 | 7062.0 |
| SRSF9 | -2009.0 | -5029.0 |
| SSRP1 | 2663.0 | 4754.0 |
| ST6GALNAC4 | -365.0 | 4860.0 |
| STARD3 | -3871.0 | -6390.0 |
| STK25 | 6890.0 | 2565.0 |
| TACC3 | 5297.0 | 4254.0 |
| TAF10 | -3030.0 | 2638.0 |
| TAF1C | 895.0 | -5428.0 |
| TAF4 | 2448.0 | 3472.0 |
| TBL3 | 5799.0 | -3253.0 |
| TECR | 1529.0 | -251.0 |
| THAP7 | -4662.0 | 4597.0 |
| THOC6 | -3723.0 | -3958.0 |
| TKT | 8181.0 | 2150.0 |
| TLE5 | 376.0 | 3434.0 |
| TMED9 | -5309.0 | -1036.0 |
| TMEM259 | -1139.0 | -4368.0 |
| TNFRSF14 | 872.0 | -1648.0 |
| TP53 | 2557.0 | -3561.0 |
| TRAPPC2 | -3263.0 | 6403.0 |
| TRIM28 | -1390.0 | -6154.0 |
| TSPAN14 | -6627.0 | 1158.0 |
| TSR3 | 4228.0 | -5856.0 |
| TSSC4 | -1289.0 | -2173.0 |
| TSTA3 | 4940.0 | 53.0 |
| U2AF2 | -2150.0 | -825.0 |
| UBE2M | 3424.0 | 2257.0 |
| UBE2S | 4549.0 | -1742.0 |
| UBN1 | -3031.0 | -5794.0 |
| UCP2 | 6987.0 | 4595.0 |
| VPS51 | 3048.0 | -6458.0 |
| VPS9D1 | -819.0 | -4773.0 |
| WDR18 | -5000.0 | -3150.0 |
| WDR74 | -544.0 | 3937.0 |
| XAB2 | 2873.0 | 3916.0 |
| YJU2 | 700.0 | -3393.0 |
| ZBTB17 | 2405.0 | -590.0 |
| ZNF512B | 7028.0 | -6394.0 |
GSE40225_WT_VS_RIP_B7X_DIABETIC_MOUSE_PANCREATIC_CD8_TCELL_DN
| metric | value |
|---|---|
| setSize | 179 |
| pMANOVA | 0.00515 |
| p.adjustMANOVA | 0.0127 |
| s.dist | 0.153 |
| s.diabetes | -0.0842 |
| s.mitoG | 0.128 |
| p.diabetes | 0.0525 |
| p.mitoG | 0.00312 |
| Gene | diabetes | mitoG |
|---|---|---|
| TOP1 | -7160 | 8404 |
| USO1 | -6682 | 8749 |
| RDX | -6580 | 7989 |
| MANF | -7276 | 7166 |
| SOS1 | -6566 | 7698 |
| GALNT1 | -6827 | 6806 |
| HDGF | -5612 | 7365 |
| UBE2J1 | -4894 | 8195 |
| POMP | -6322 | 6114 |
| ARF4 | -6276 | 6071 |
| ACOX1 | -7025 | 5178 |
| PDXDC1 | -5276 | 6727 |
| NFIL3 | -7012 | 5060 |
| LZTFL1 | -4679 | 7473 |
| SPTY2D1 | -4612 | 7562 |
| SRP72 | -4187 | 8263 |
| IDH3G | -4880 | 6728 |
| IGF1 | -6185 | 5101 |
| PSMA5 | -6660 | 4497 |
| TFDP1 | -6289 | 4476 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| AAAS | 5561.0 | -2261.0 |
| AARS1 | -4867.0 | 5015.0 |
| ACOX1 | -7025.0 | 5178.0 |
| ADRM1 | -6170.0 | -477.0 |
| AGPS | -7336.0 | 594.0 |
| AIFM1 | -6115.0 | -1984.0 |
| ALDH18A1 | 140.0 | -1710.0 |
| ALG14 | -5434.0 | 4618.0 |
| ALG5 | -3605.0 | -1803.0 |
| ALG9 | -2677.5 | -938.5 |
| ARF4 | -6276.0 | 6071.0 |
| ARFGAP3 | -1901.0 | 5934.0 |
| ARHGDIA | 7151.0 | -2224.0 |
| ATG13 | 1287.0 | -2327.0 |
| BAK1 | 7177.0 | 3473.0 |
| BCAR3 | 5770.0 | 4210.0 |
| BIN2 | -3519.0 | 1037.0 |
| BMP6 | 7829.0 | 1032.0 |
| BRCA1 | -2450.0 | 4279.0 |
| BSCL2 | 4891.0 | -4593.0 |
| BSG | -3166.0 | 5032.0 |
| BUD23 | -342.0 | -219.0 |
| C20orf96 | 4344.0 | -2715.0 |
| CABLES1 | 5120.0 | -5245.0 |
| CACNB1 | 6319.0 | 483.0 |
| CACNB3 | 7396.0 | 5397.0 |
| CAMKK2 | 4860.0 | -3845.0 |
| CCNE2 | 2080.0 | 3324.0 |
| CDC25A | -5099.0 | 1807.0 |
| CDCA4 | 4122.0 | 2492.0 |
| CDIPT | -719.0 | 3299.0 |
| CENPA | -371.0 | -2996.0 |
| CENPI | -1339.0 | -6050.0 |
| CHST2 | 2012.0 | 6764.0 |
| CKS2 | 2618.0 | 3705.0 |
| CLDND1 | -5798.0 | 2570.0 |
| COPB1 | -2848.0 | 7946.0 |
| COX18 | 5019.0 | 1575.0 |
| CRIP1 | 2892.5 | 6423.5 |
| CYFIP1 | 3175.0 | 7476.0 |
| DAXX | -867.0 | 1599.0 |
| DENND1B | -3640.0 | 6236.0 |
| DEPTOR | 5474.0 | 3038.0 |
| DUSP16 | -3468.0 | 8092.0 |
| ECH1 | 2316.0 | 6370.0 |
| ECHS1 | 1581.0 | 1330.0 |
| ECT2 | -2506.0 | 1653.0 |
| EDRF1 | -2746.0 | 4436.0 |
| EIF2AK3 | -6386.0 | 3372.0 |
| ENO1 | 8244.0 | 7737.0 |
| FAM160B1 | 3255.0 | 5472.0 |
| FAM214B | 7990.0 | -869.0 |
| FBXW8 | 7356.0 | -1698.0 |
| FRRS1 | -6261.0 | 1581.0 |
| FTSJ1 | -914.0 | 3461.0 |
| GALNT1 | -6827.0 | 6806.0 |
| GBA | -5712.0 | -3677.0 |
| GBF1 | -6681.0 | 3356.0 |
| GEMIN7 | -3021.0 | 21.0 |
| GPN2 | 954.0 | -3184.0 |
| H2AZ1 | -980.0 | 4206.0 |
| HDGF | -5612.0 | 7365.0 |
| HMGB2 | 6857.0 | 1304.0 |
| HMOX2 | -1566.0 | 6596.0 |
| IARS1 | -5409.0 | 3400.0 |
| IDE | -1263.0 | 3492.0 |
| IDH3G | -4880.0 | 6728.0 |
| IFNAR1 | -1479.0 | 4534.0 |
| IGF1 | -6185.0 | 5101.0 |
| IQGAP2 | 8068.0 | 6890.0 |
| IRF7 | -4522.0 | 2058.0 |
| JTB | -4066.5 | 5444.5 |
| KCNN3 | 244.0 | -1001.0 |
| KIF4A | 1014.0 | 6024.0 |
| KLHDC4 | 1905.0 | -1814.0 |
| KNTC1 | 3675.0 | -2190.0 |
| LIN52 | -355.0 | 4271.0 |
| LZTFL1 | -4679.0 | 7473.0 |
| MAD2L1 | 4196.0 | -2495.0 |
| MAN2A1 | 8162.0 | 5453.0 |
| MAN2B1 | -3804.0 | -5934.0 |
| MANF | -7276.0 | 7166.0 |
| MAPKAPK3 | 7267.0 | -4297.0 |
| MARS1 | -1343.0 | 1975.0 |
| MARVELD2 | 844.0 | 3416.0 |
| MCAT | 1596.0 | -4830.0 |
| MCRS1 | 3404.0 | 504.0 |
| MDFIC | -2552.0 | 8519.0 |
| MDH2 | 3713.0 | 4456.0 |
| MDM2 | 5569.0 | 7967.0 |
| METTL1 | -871.0 | -234.0 |
| MFSD2A | -3164.0 | -1561.0 |
| MLEC | -7059.0 | -620.0 |
| MLKL | 6050.0 | 1003.0 |
| MLST8 | -977.0 | -1211.0 |
| MRPL4 | 2533.0 | -622.0 |
| MT2A | 8239.0 | 7031.0 |
| MTRR | -1959.0 | 968.0 |
| MYCBP | -2519.5 | 7901.5 |
| N4BP2 | 6330.0 | 2179.0 |
| NAGLU | -4620.0 | -6515.0 |
| NCALD | 5836.0 | 5345.0 |
| NCAPH | -438.0 | 2508.0 |
| NDUFB7 | 5336.0 | 2347.0 |
| NECAB3 | 4996.0 | -2022.0 |
| NEIL3 | 3195.0 | -5023.0 |
| NFIL3 | -7012.0 | 5060.0 |
| NFXL1 | -6799.0 | -2927.0 |
| NOA1 | -5924.0 | 890.0 |
| NOD2 | -6286.0 | 2681.0 |
| OAS1 | 3456.0 | -6726.0 |
| OPTN | 8052.0 | 6703.0 |
| PAM | 2452.0 | 1723.0 |
| PDXDC1 | -5276.0 | 6727.0 |
| PGM3 | -5155.0 | -58.0 |
| PIEZO1 | 8094.0 | -2168.0 |
| PIK3C2A | -262.0 | 8592.0 |
| PIM1 | -3615.0 | 5315.0 |
| PKP4 | -3865.0 | 5106.0 |
| PLD3 | 5879.0 | -2713.0 |
| PLEKHA7 | 7220.0 | -6755.0 |
| PLK4 | 4005.0 | 1167.0 |
| PMM2 | -447.0 | -333.0 |
| PMVK | 6667.0 | -5342.0 |
| POMP | -6322.0 | 6114.0 |
| POU2AF1 | -61.0 | 3658.0 |
| PPAT | 6637.0 | 6980.0 |
| PRC1 | 669.0 | 103.0 |
| PSEN2 | -3057.0 | -1025.0 |
| PSMA5 | -6660.0 | 4497.0 |
| PSMD9 | 7707.5 | -894.5 |
| PTPN1 | 6946.0 | 3039.0 |
| PTTG1 | 6122.5 | 3485.5 |
| PYGB | 5808.0 | 5273.0 |
| RAB39B | -1021.0 | 6431.0 |
| RANBP3 | -167.0 | 2335.0 |
| RBM47 | 1021.0 | -1394.0 |
| RDX | -6580.0 | 7989.0 |
| RINT1 | -2729.0 | -5208.0 |
| RTRAF | -2127.0 | 8772.0 |
| SCAMP2 | -1216.0 | -2096.0 |
| SDF2L1 | -7228.0 | 2132.0 |
| SEPHS1 | 2030.0 | 4351.0 |
| SESN2 | -4377.0 | 1285.0 |
| SLC12A4 | 5724.0 | 5028.0 |
| SLC17A9 | 3252.0 | -4870.0 |
| SLC2A8 | 8092.0 | -6699.0 |
| SLC35C1 | -399.0 | -4005.0 |
| SLC35E1 | -5606.0 | 67.0 |
| SLFN13 | -6911.0 | 2609.0 |
| SND1 | -6474.0 | -3181.0 |
| SOS1 | -6566.0 | 7698.0 |
| SPC24 | 5810.0 | -1008.0 |
| SPTY2D1 | -4612.0 | 7562.0 |
| SRP68 | -2952.0 | 5498.0 |
| SRP72 | -4187.0 | 8263.0 |
| SRPK1 | -6945.0 | 287.0 |
| SSR4 | 4091.0 | 1326.0 |
| TFDP1 | -6289.0 | 4476.0 |
| TICRR | -474.0 | -2001.0 |
| TMED3 | -6313.0 | 3992.0 |
| TMEM184B | 79.0 | 4353.0 |
| TOP1 | -7160.0 | 8404.0 |
| TRIM47 | -6869.0 | -549.0 |
| TUBG1 | -743.0 | 6237.0 |
| TWSG1 | 6722.0 | 5606.0 |
| UAP1 | -7245.0 | 1255.0 |
| UBE2J1 | -4894.0 | 8195.0 |
| UBE2S | 4549.0 | -1742.0 |
| UBE4A | -6479.0 | 2398.0 |
| UBXN6 | 4514.0 | 6075.0 |
| UCHL5 | 539.0 | 3983.0 |
| ULK2 | -6626.0 | 600.0 |
| USO1 | -6682.0 | 8749.0 |
| XK | -1266.0 | 5749.0 |
| YIF1B | 5058.0 | -3729.0 |
| ZC3HAV1L | 1390.0 | -3103.0 |
| ZDHHC9 | -2745.0 | -1163.0 |
| ZNRD2 | 5305.0 | -6074.0 |
GSE9006_TYPE_1_DIABETES_AT_DX_VS_4MONTH_POST_DX_PBMC_DN
| metric | value |
|---|---|
| setSize | 148 |
| pMANOVA | 0.00393 |
| p.adjustMANOVA | 0.0104 |
| s.dist | 0.141 |
| s.diabetes | 0.0865 |
| s.mitoG | 0.112 |
| p.diabetes | 0.0696 |
| p.mitoG | 0.0192 |
| Gene | diabetes | mitoG |
|---|---|---|
| CA8 | 7188 | 8414 |
| ATP2B4 | 7691 | 7255 |
| CBR1 | 8220 | 6483 |
| S100A10 | 7779 | 5985 |
| ABHD6 | 6359 | 7038 |
| RGS5 | 5300 | 8040 |
| COL6A1 | 6555 | 6347 |
| GSTO1 | 8023 | 4922 |
| TIMM8A | 4496 | 7741 |
| RUFY2 | 6866 | 4915 |
| LBP | 4550 | 7403 |
| ADAMTS5 | 4732 | 6838 |
| SPSB1 | 7434 | 4252 |
| RPL19 | 4654 | 6782 |
| SELENOW | 6572 | 4775 |
| BMPR1B | 5157 | 5691 |
| TERF2 | 5515 | 5270 |
| EIF3K | 4728 | 6062 |
| LPP | 7785 | 3122 |
| IFT46 | 5958 | 4026 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| ABHD6 | 6359.0 | 7038.0 |
| ADAMTS5 | 4732.0 | 6838.0 |
| ADGRA2 | 6742.0 | -4913.0 |
| ARFRP1 | 702.0 | -6512.0 |
| ARHGAP35 | -2056.0 | 7180.0 |
| ARMCX4 | -5810.0 | 6643.0 |
| ATAT1 | -6757.0 | -6199.0 |
| ATP2B4 | 7691.0 | 7255.0 |
| ATP5F1C | 164.0 | 8242.0 |
| ATXN3L | 633.5 | 4150.5 |
| BMPR1B | 5157.0 | 5691.0 |
| BOLA1 | 2756.0 | -4124.0 |
| C21orf91 | -4198.0 | 8254.0 |
| C2orf68 | -4445.0 | -3173.0 |
| CA8 | 7188.0 | 8414.0 |
| CBR1 | 8220.0 | 6483.0 |
| CCDC51 | 3605.0 | -4365.0 |
| CCT5 | -6746.0 | 6513.0 |
| CD48 | -1928.0 | 2626.0 |
| CD52 | -3982.0 | 3448.0 |
| CD53 | -3501.0 | 7525.0 |
| CDKN2C | 6608.0 | -3067.0 |
| CFAP43 | -4048.0 | 2739.0 |
| CHD9 | -6925.0 | 8050.0 |
| CNOT1 | -2585.0 | 3418.0 |
| COA4 | -3012.0 | 3241.0 |
| COL6A1 | 6555.0 | 6347.0 |
| COMMD3 | -4289.0 | 8822.0 |
| COQ6 | 1950.0 | -3453.0 |
| COX4I1 | 6324.0 | -2473.0 |
| CSRNP2 | 6469.0 | 1246.0 |
| DARS2 | -5166.0 | 329.0 |
| DNAJC28 | 3205.0 | 1021.0 |
| DOCK3 | -1237.0 | 4419.0 |
| DYNLL1 | -6952.0 | 7645.0 |
| DYNLRB1 | 5057.0 | -2847.0 |
| DZANK1 | 5408.0 | -4689.0 |
| EEF1B2 | 1782.0 | 477.0 |
| EIF2S2 | -3307.0 | 8799.0 |
| EIF3K | 4728.0 | 6062.0 |
| EPOR | 7888.0 | -2666.0 |
| EPS8L3 | 3849.0 | 511.0 |
| ESRP2 | 5000.0 | -3533.0 |
| FABP1 | 289.0 | -1810.0 |
| FAM111A | -3910.0 | 3549.0 |
| FHOD3 | 7408.0 | -6090.0 |
| FMO4 | 7029.0 | 569.0 |
| FOXO4 | 257.0 | -4431.0 |
| FZD5 | 2921.0 | 2259.0 |
| GPR171 | -4112.0 | 6669.0 |
| GPR22 | -1234.0 | -3658.0 |
| GRIA1 | 3840.0 | -983.0 |
| GSTO1 | 8023.0 | 4922.0 |
| GUCY1A1 | 1918.0 | 7519.0 |
| H2AW | -5259.0 | 4003.0 |
| HAX1 | -7176.0 | 4152.0 |
| HECTD4 | -439.0 | -5909.0 |
| HINT1 | 3946.0 | 413.0 |
| HMGCL | 1207.0 | -3452.0 |
| HOXC8 | 5791.0 | -438.0 |
| HPX | 2769.0 | 2190.0 |
| IER3IP1 | -246.5 | -3466.5 |
| IFT46 | 5958.0 | 4026.0 |
| ING4 | -4464.0 | -4099.0 |
| INO80B | 6545.5 | -3302.5 |
| ITFG2 | 826.0 | -4600.0 |
| LAMTOR5 | 4258.0 | 4393.0 |
| LBP | 4550.0 | 7403.0 |
| LIF | 352.0 | 2557.0 |
| LIPE | 2527.0 | 415.0 |
| LMO4 | -4999.0 | 1286.0 |
| LPP | 7785.0 | 3122.0 |
| LRRC20 | 7602.0 | -584.0 |
| LRRC75B | -548.0 | -2539.0 |
| LSM1 | 1559.0 | 3093.0 |
| MCCC1 | -5695.0 | 1708.0 |
| MDH1 | 4402.0 | 4491.0 |
| MGST3 | 8217.0 | 479.0 |
| MPV17 | -5777.0 | 4042.0 |
| MRPL17 | -3013.0 | 6746.0 |
| MRPL18 | -4156.0 | 1438.0 |
| MRPS33 | -3942.0 | 3752.0 |
| MYL7 | 6630.0 | -336.0 |
| NAP1L4 | 225.0 | -2423.0 |
| NDUFA3 | 4319.0 | 82.0 |
| NRCAM | 3619.0 | 5428.0 |
| OXA1L | 4609.0 | -4940.0 |
| PBLD | 2456.0 | -2483.0 |
| PDE8A | -3329.0 | 7592.0 |
| PFDN5 | 2482.0 | 8089.0 |
| PGM3 | -5155.0 | -58.0 |
| PHACTR4 | 420.0 | 3217.0 |
| PHF11 | -7148.0 | 3818.0 |
| PIP4K2B | -937.0 | 1458.0 |
| POGLUT1 | -1880.0 | 2758.0 |
| POLR2J | 1742.0 | 3424.0 |
| PPP2R5B | 627.0 | 5414.0 |
| PPT2 | -5191.5 | -2667.5 |
| PRSS12 | 456.0 | 2357.0 |
| RABEPK | 2166.0 | 960.0 |
| RABIF | -2521.0 | -1135.0 |
| RALYL | -4745.0 | -993.0 |
| RGS10 | -3271.0 | 4787.0 |
| RGS5 | 5300.0 | 8040.0 |
| RNF113A | -3023.0 | 3421.0 |
| RPA3 | 3029.0 | 1440.0 |
| RPL12 | 6107.0 | -5604.0 |
| RPL19 | 4654.0 | 6782.0 |
| RPL21 | -1686.0 | 8463.0 |
| RPL24 | -409.0 | 6813.0 |
| RPS13 | 7174.0 | 315.0 |
| RPS16 | 6244.0 | 1119.0 |
| RUFY2 | 6866.0 | 4915.0 |
| RUFY3 | 5428.0 | -5971.0 |
| S100A10 | 7779.0 | 5985.0 |
| SAP18 | -2023.0 | 7183.0 |
| SDHAF1 | 3386.0 | 2256.0 |
| SELENOW | 6572.0 | 4775.0 |
| SEMA6A | -6678.0 | 6683.0 |
| SEMA6C | 6649.0 | -2213.0 |
| SERF2 | -2395.0 | -2526.0 |
| SLC16A4 | 3434.0 | 6334.0 |
| SLC35E2B | 1081.0 | 797.0 |
| SLC5A3 | -5294.0 | -1122.0 |
| SLC66A1 | -1315.0 | -5738.0 |
| SLC66A3 | 3663.0 | 5856.0 |
| SNRPC | 5050.0 | 2270.0 |
| SNRPD2 | 2697.0 | 71.0 |
| SOD3 | -1080.0 | -2376.0 |
| SPSB1 | 7434.0 | 4252.0 |
| SS18L2 | 2519.0 | 4485.0 |
| SYNRG | -6000.0 | 2901.0 |
| TAOK2 | 7040.0 | -3998.0 |
| TEP1 | 7484.0 | -6128.0 |
| TERF2 | 5515.0 | 5270.0 |
| TFB1M | -154.0 | -4984.0 |
| TGFB3 | -1546.0 | 8322.0 |
| TIMM8A | 4496.0 | 7741.0 |
| TIMM8B | -1186.0 | 7371.0 |
| TM6SF2 | 8051.0 | 1210.0 |
| TNPO3 | -3142.0 | 2781.0 |
| TTC1 | -896.0 | 7387.0 |
| UBA52 | 7488.0 | -4269.0 |
| UQCR11 | 5012.5 | -3179.5 |
| VPS37A | -5968.0 | 8308.0 |
| XCL1 | -1812.5 | 2070.5 |
| YIPF6 | -4393.0 | 6442.0 |
| ZMYM6 | -6630.0 | -5108.0 |
HP_NEPHROPATHY
| metric | value |
|---|---|
| setSize | 90 |
| pMANOVA | 0.046 |
| p.adjustMANOVA | 0.0852 |
| s.dist | 0.135 |
| s.diabetes | 0.0887 |
| s.mitoG | 0.101 |
| p.diabetes | 0.146 |
| p.mitoG | 0.0974 |
| Gene | diabetes | mitoG |
|---|---|---|
| CAVIN1 | 7138 | 8770 |
| SCNN1G | 6471 | 7958 |
| MYH9 | 7189 | 7115 |
| MT-ND5 | 6025 | 8007 |
| SCARB2 | 6376 | 7312 |
| MT-ND1 | 5618 | 7323 |
| MT-ND6 | 5059 | 8045 |
| MT-CO1 | 6781 | 5983 |
| CD151 | 6017 | 4815 |
| SCNN1B | 7229 | 4000 |
| SCNN1A | 8056 | 3548 |
| B2M | 5339 | 4978 |
| FGA | 4508 | 5893 |
| FOXI1 | 6075 | 4294 |
| NUP107 | 3423 | 7169 |
| FAM20A | 4604 | 5067 |
| KCNJ10 | 3384 | 6290 |
| MAFB | 8140 | 2473 |
| WT1 | 5237 | 3586 |
| MT-CO3 | 2273 | 6269 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| AGPAT2 | -4051.0 | -2429.0 |
| ALG1 | -2121.0 | -4072.0 |
| APOA1 | 3682.0 | -305.0 |
| APPL1 | 940.0 | 7089.0 |
| B2M | 5339.0 | 4978.0 |
| BSCL2 | 4891.0 | -4593.0 |
| CAV1 | 875.0 | 7970.0 |
| CAVIN1 | 7138.0 | 8770.0 |
| CC2D2A | 1751.0 | -2392.0 |
| CCND1 | 7933.0 | -1628.0 |
| CD151 | 6017.0 | 4815.0 |
| CEP120 | 3471.0 | 2793.0 |
| CEP290 | -2988.0 | 5308.0 |
| CISD2 | -5462.0 | 6479.0 |
| CLDN19 | 2681.0 | -450.0 |
| COL4A1 | -1913.0 | 7738.0 |
| DYNC2H1 | -1831.0 | -3937.0 |
| DYNC2LI1 | 46.0 | 303.0 |
| EIF2AK3 | -6386.0 | 3372.0 |
| FAM20A | 4604.0 | 5067.0 |
| FGA | 4508.0 | 5893.0 |
| FOS | 827.0 | 3751.0 |
| FOXI1 | 6075.0 | 4294.0 |
| GLA | 1196.0 | 3449.0 |
| HIC1 | 1899.0 | 3532.0 |
| HNF1A | 7450.0 | -6675.0 |
| HNF4A | -6855.0 | 4619.0 |
| HPRT1 | -5564.0 | 8025.0 |
| IFT140 | 1480.0 | -4541.0 |
| IFT172 | 3902.0 | -5651.0 |
| IFT80 | -5454.0 | -2479.0 |
| INPP5E | 6856.0 | -5834.0 |
| KCNJ10 | 3384.0 | 6290.0 |
| KCNJ11 | 2961.0 | -3265.0 |
| KLF11 | 7284.0 | 1719.0 |
| LAGE3 | 5065.0 | 1002.0 |
| LMX1B | 5720.0 | 823.0 |
| MAFB | 8140.0 | 2473.0 |
| MEFV | -4277.0 | 5186.0 |
| MMACHC | 1165.0 | 5604.0 |
| MT-CO1 | 6781.0 | 5983.0 |
| MT-CO2 | 293.0 | -1711.0 |
| MT-CO3 | 2273.0 | 6269.0 |
| MT-ND1 | 5618.0 | 7323.0 |
| MT-ND4 | 1752.0 | 7883.0 |
| MT-ND5 | 6025.0 | 8007.0 |
| MT-ND6 | 5059.0 | 8045.0 |
| MYH9 | 7189.0 | 7115.0 |
| NLRP3 | -5337.0 | 1863.0 |
| NOD2 | -6286.0 | 2681.0 |
| NPHP1 | 705.0 | 5221.0 |
| NUP107 | 3423.0 | 7169.0 |
| NUP133 | 2759.0 | -4113.0 |
| OSGEP | 1999.0 | 983.0 |
| PAFAH1B1 | -3995.0 | 8266.0 |
| PAX6 | -2974.0 | 1272.0 |
| PPARG | -3636.0 | 5654.0 |
| PRDX1 | -6422.0 | 8698.0 |
| PRODH | 6792.5 | -2080.5 |
| RPGRIP1L | -5538.0 | -2125.0 |
| SCARB2 | 6376.0 | 7312.0 |
| SCNN1A | 8056.0 | 3548.0 |
| SCNN1B | 7229.0 | 4000.0 |
| SCNN1G | 6471.0 | 7958.0 |
| SEC61A1 | -6475.0 | -2203.0 |
| SLC26A4 | -3154.0 | -406.0 |
| TMEM138 | 1311.0 | -379.0 |
| TMEM216 | 639.0 | -5653.0 |
| TMEM231 | 4190.0 | -2063.0 |
| TMEM237 | -7028.0 | 644.0 |
| TMEM67 | -3894.0 | -1057.0 |
| TP53RK | -488.0 | -6739.0 |
| TPRKB | 4020.0 | -3573.0 |
| TREX1 | 1252.0 | 2779.0 |
| TTC21B | -657.0 | -2310.0 |
| TTR | -6090.0 | 3451.0 |
| UMOD | -6036.0 | -707.0 |
| VIPAS39 | -1721.0 | 3736.0 |
| VPS33B | 2918.5 | -5911.5 |
| WAS | -11.0 | 299.0 |
| WDR19 | 5951.0 | -1726.0 |
| WDR34 | 5448.0 | -6192.0 |
| WDR4 | -6102.0 | -4331.0 |
| WDR60 | -383.0 | -3158.0 |
| WDR73 | -2550.0 | 2299.0 |
| WFS1 | 7688.0 | -3009.0 |
| WIPF1 | -3718.0 | 7829.0 |
| WT1 | 5237.0 | 3586.0 |
| YWHAE | -2079.0 | 7315.0 |
| ZNF423 | -18.0 | 2643.0 |
GSE9006_TYPE_1_DIABETES_AT_DX_VS_1MONTH_POST_DX_PBMC_UP
| metric | value |
|---|---|
| setSize | 187 |
| pMANOVA | 0.015 |
| p.adjustMANOVA | 0.0326 |
| s.dist | 0.132 |
| s.diabetes | -0.0563 |
| s.mitoG | 0.119 |
| p.diabetes | 0.185 |
| p.mitoG | 0.00511 |
| Gene | diabetes | mitoG |
|---|---|---|
| HNRNPA3 | -6985 | 8827 |
| HSP90B1 | -7279 | 8368 |
| PDIA3 | -7283 | 7821 |
| PDIA4 | -7329 | 7729 |
| HSPA5 | -7309 | 7589 |
| KLHL2 | -6669 | 8214 |
| RPN1 | -7121 | 7464 |
| ADAM10 | -6444 | 8149 |
| THBD | -6500 | 7788 |
| YWHAZ | -5614 | 8512 |
| PPP4R3A | -5758 | 7453 |
| NSD1 | -6917 | 6189 |
| KDELR2 | -4969 | 8520 |
| CORO1C | -6048 | 6789 |
| MSL2 | -6222 | 6310 |
| ACTR2 | -5189 | 7356 |
| HNRNPU | -5219 | 7082 |
| P4HB | -6743 | 5398 |
| RBBP4 | -6148 | 5835 |
| PAK2 | -4906 | 6708 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| AAMP | 69.0 | -4287.0 |
| ABCF1 | 1824.0 | -770.0 |
| ABCF3 | -1985.0 | -3254.0 |
| ACO2 | 7295.0 | 7282.0 |
| ACTG1 | -1502.0 | 1482.0 |
| ACTR2 | -5189.0 | 7356.0 |
| ADAM10 | -6444.0 | 8149.0 |
| AGPAT3 | -4447.0 | -444.0 |
| AGPS | -7336.0 | 594.0 |
| AHCY | -3362.0 | -6342.0 |
| ALDOA | 6979.5 | 3652.5 |
| AMBRA1 | 51.0 | -5388.0 |
| AMDHD2 | -5012.5 | -6718.5 |
| ANP32A | 3020.5 | 6935.5 |
| ARAF | 4130.0 | -5879.0 |
| ARF6 | -804.0 | 229.0 |
| ARL6IP1 | -6592.5 | -1456.5 |
| ARPC4 | 3077.0 | 1525.0 |
| ATP2A2 | -7302.0 | 1164.0 |
| ATP5F1D | 5225.0 | 673.0 |
| ATP8B2 | -690.0 | 6070.0 |
| BANF1 | 3561.0 | -458.0 |
| BGLAP | -4940.0 | -647.0 |
| BMPR2 | 512.0 | 7927.0 |
| BRMS1 | 1673.0 | 7971.0 |
| BSG | -3166.0 | 5032.0 |
| BTG1 | 7930.0 | 4557.0 |
| CCDC22 | -4166.0 | -3221.0 |
| CCL2 | -1079.0 | 3167.0 |
| CDC37 | -682.0 | -4414.0 |
| CDCA4 | 4122.0 | 2492.0 |
| CDK2 | 6186.0 | -4240.0 |
| CDK9 | 315.0 | -5322.0 |
| CDT1 | 6848.0 | -4131.0 |
| CHFR | 686.0 | 5588.0 |
| COPG1 | -3891.0 | 3599.0 |
| COPS7B | -2394.0 | -5916.0 |
| CORO1C | -6048.0 | 6789.0 |
| CTSD | 5035.5 | 6716.5 |
| CXCR4 | 4516.0 | 7547.0 |
| CYBA | -4719.0 | -4200.0 |
| CYBB | -5520.0 | 5307.0 |
| CYP51A1 | 39.0 | -254.0 |
| DAZAP2 | 5976.0 | 2413.0 |
| DDIT4 | 5684.0 | 4879.0 |
| DDX3X | 3775.0 | 8058.0 |
| DGCR2 | 6927.0 | -6630.0 |
| DNAJA2 | -3327.0 | 8515.0 |
| DNAJC17 | 2361.0 | 3774.0 |
| DUSP1 | -2905.0 | -1666.0 |
| DUSP10 | 4557.0 | 5745.0 |
| ECSIT | -3596.0 | 1408.0 |
| EGLN1 | -4261.5 | -1804.5 |
| EHD4 | 5130.0 | 8802.0 |
| ELMO1 | -4833.0 | 4917.0 |
| EWSR1 | 7288.0 | -6211.0 |
| FARSA | -2969.0 | -5485.0 |
| FKBP5 | 6201.0 | 5807.0 |
| FLI1 | -110.0 | 7996.0 |
| FZR1 | 3996.0 | -5000.0 |
| GALNT2 | -4331.0 | 2581.0 |
| GLOD4 | 1193.0 | 3577.0 |
| GLUD1 | 8064.5 | 3730.5 |
| GLUD2 | 8064.5 | 3730.5 |
| GLUL | 7900.0 | 3064.0 |
| GOLPH3 | -4347.0 | 6453.0 |
| GPAA1 | 696.0 | -5319.0 |
| GPI | 4816.0 | 5422.0 |
| GRAMD4 | -6920.0 | -604.0 |
| GSN | 7535.0 | 7997.0 |
| GSR | -2480.0 | 4329.0 |
| HBEGF | -6694.0 | -80.0 |
| HERPUD1 | 924.0 | 3108.0 |
| HLX | -778.0 | 6383.0 |
| HMGB2 | 6857.0 | 1304.0 |
| HNRNPA1 | 7891.0 | -6290.0 |
| HNRNPA3 | -6985.0 | 8827.0 |
| HNRNPK | -808.0 | 7246.0 |
| HNRNPR | -3972.0 | 1045.0 |
| HNRNPU | -5219.0 | 7082.0 |
| HSP90B1 | -7279.0 | 8368.0 |
| HSPA5 | -7309.0 | 7589.0 |
| HSPA9 | -566.0 | 8181.0 |
| HYOU1 | -7255.0 | 4009.0 |
| IER3 | 2411.0 | 7011.0 |
| IFIT3 | 4120.0 | 6607.0 |
| IGKC | -2925.0 | 7318.0 |
| ILF2 | 2872.0 | 3070.0 |
| INTS3 | -6130.0 | -3040.0 |
| JUNB | 4544.0 | 2430.0 |
| KDELR2 | -4969.0 | 8520.0 |
| KIF2C | 2591.0 | -1946.0 |
| KIF4A | 1014.0 | 6024.0 |
| KLF2 | 3944.0 | 2031.0 |
| KLHL2 | -6669.0 | 8214.0 |
| LSM12 | -2869.0 | 4929.0 |
| MAFB | 8140.0 | 2473.0 |
| MAP3K8 | 656.0 | 2671.0 |
| MAP4K4 | 3979.0 | 7914.0 |
| MAPRE1 | -3633.0 | 8509.0 |
| MARCKS | -1781.0 | 5038.0 |
| MARCKSL1 | -107.0 | 7707.0 |
| MFN2 | 7230.0 | -1391.0 |
| MRPL12 | -2913.0 | 4144.0 |
| MSL2 | -6222.0 | 6310.0 |
| NAPG | 3323.0 | 2180.0 |
| NCAPH2 | 3662.0 | -3375.0 |
| NCL | 6850.0 | 8762.0 |
| NDUFV1 | 4313.0 | -2431.0 |
| NFE2L2 | 1459.0 | 8443.0 |
| NFYA | -6056.0 | 1269.0 |
| NRAS | 3837.0 | 7903.0 |
| NSD1 | -6917.0 | 6189.0 |
| NT5DC2 | -7177.0 | 1331.0 |
| ODF2 | 8196.0 | -5679.0 |
| OSTF1 | 6553.0 | 5854.0 |
| P4HB | -6743.0 | 5398.0 |
| PABPC4 | 2846.0 | -3784.0 |
| PAK2 | -4906.0 | 6708.0 |
| PDIA3 | -7283.0 | 7821.0 |
| PDIA4 | -7329.0 | 7729.0 |
| PDK4 | 3864.0 | 4092.0 |
| PFN1 | -3462.0 | -4129.0 |
| PHF21A | -2368.0 | 829.0 |
| PIM1 | -3615.0 | 5315.0 |
| PPIB | 2973.0 | 133.0 |
| PPIF | 6302.0 | -1305.0 |
| PPP4C | 851.0 | -5414.0 |
| PPP4R3A | -5758.0 | 7453.0 |
| PRCC | -3064.0 | -3244.0 |
| PRKDC | -5092.0 | 3381.0 |
| PRPF6 | 3568.0 | 279.0 |
| PSMC3 | -4285.0 | 3386.0 |
| PSPN | -1715.0 | -1537.0 |
| PTBP1 | -4264.0 | -2729.0 |
| PTBP3 | 5856.0 | 7175.0 |
| PTX3 | -4488.0 | -2545.0 |
| PUF60 | -754.0 | 731.0 |
| RAB1B | -80.0 | -4574.0 |
| RAB8A | -855.0 | 2596.0 |
| RABAC1 | 7530.0 | -5906.0 |
| RASA3 | 7998.0 | 3778.0 |
| RBBP4 | -6148.0 | 5835.0 |
| RBM3 | 8175.0 | 5192.0 |
| RBM42 | -841.0 | -4924.0 |
| RCL1 | 5218.0 | 4620.0 |
| REX1BD | 1924.0 | -3848.0 |
| RPN1 | -7121.0 | 7464.0 |
| RRP12 | 3149.0 | 2306.0 |
| RTN3 | -2760.0 | 5623.0 |
| SAFB | -1933.0 | -1132.0 |
| SAFB2 | 3321.0 | -6673.0 |
| SART1 | 2632.0 | -1920.0 |
| SEC31A | 835.0 | -552.0 |
| SH3GLB2 | 284.0 | -2915.0 |
| SIDT1 | -2430.0 | -1174.0 |
| SLC25A20 | 6499.0 | 4961.0 |
| SLC39A7 | -6230.0 | 880.0 |
| SLC6A6 | 6597.0 | -1579.0 |
| SMU1 | -2457.0 | 8160.0 |
| SNRNP40 | 4613.0 | 2666.0 |
| SOCS1 | -253.0 | -5520.0 |
| SOCS3 | 4231.0 | 7185.0 |
| SRSF9 | -2009.0 | -5029.0 |
| STT3A | -6845.0 | 4709.0 |
| STX11 | 608.0 | -2244.0 |
| SVIL | -3260.0 | -6020.0 |
| TBL3 | 5799.0 | -3253.0 |
| TESK2 | 2566.0 | -4280.0 |
| THBD | -6500.0 | 7788.0 |
| THOC6 | -3723.0 | -3958.0 |
| TMCO3 | -7213.0 | 1883.0 |
| TMEM160 | 7405.0 | -6766.0 |
| TMEM259 | -1139.0 | -4368.0 |
| TMOD3 | 576.0 | 8475.0 |
| TPD52L2 | 95.0 | 3488.0 |
| TRAF3IP1 | -3542.0 | 1244.0 |
| TSC22D3 | 1663.0 | 5520.0 |
| TSPAN14 | -6627.0 | 1158.0 |
| UBE2S | 4549.0 | -1742.0 |
| UQCRC1 | 5627.0 | 1729.0 |
| WDR18 | -5000.0 | -3150.0 |
| WDR46 | 5078.0 | -4710.0 |
| XAB2 | 2873.0 | 3916.0 |
| YBX3 | 5916.0 | 4090.0 |
| YWHAZ | -5614.0 | 8512.0 |
| ZFP36L1 | -5993.0 | 4405.0 |
GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_AT_DX_DN
| metric | value |
|---|---|
| setSize | 162 |
| pMANOVA | 0.0169 |
| p.adjustMANOVA | 0.0348 |
| s.dist | 0.122 |
| s.diabetes | 0.0251 |
| s.mitoG | 0.12 |
| p.diabetes | 0.582 |
| p.mitoG | 0.00875 |
| Gene | diabetes | mitoG |
|---|---|---|
| NAMPT | 8078 | 8082 |
| MAP3K20 | 8060 | 6853 |
| G0S2 | 4904 | 8051 |
| BLM | 6861 | 5650 |
| OSTF1 | 6553 | 5854 |
| BTG2 | 6071 | 6308 |
| S1PR1 | 4311 | 7637 |
| SGK1 | 4488 | 7322 |
| SLC25A20 | 6499 | 4961 |
| STEAP4 | 4260 | 7386 |
| F2RL1 | 7281 | 4283 |
| SOCS3 | 4231 | 7185 |
| MRAS | 6507 | 4369 |
| RCL1 | 5218 | 4620 |
| RGCC | 7096 | 3390 |
| MCM3 | 3095 | 7219 |
| BHLHE41 | 8219 | 2676 |
| MANSC1 | 7247 | 3029 |
| ST14 | 7899 | 2632 |
| MAFB | 8140 | 2473 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| ABCA1 | 4025.0 | -5420.0 |
| ACKR4 | 4220.0 | -5019.0 |
| ACSL1 | 318.0 | 3006.0 |
| ADGRG3 | 6332.0 | -5786.0 |
| ADO | -1293.0 | 4866.0 |
| AKTIP | 1278.0 | 6273.0 |
| ALPL | 7672.0 | 1079.0 |
| AQP9 | -5382.0 | 1990.0 |
| ARHGDIG | 7618.0 | 2364.0 |
| ASPM | 3924.0 | -909.0 |
| AURKA | 514.0 | 6578.0 |
| BASP1 | -3933.0 | 3060.0 |
| BHLHE41 | 8219.0 | 2676.0 |
| BICDL1 | -36.0 | -2044.0 |
| BLM | 6861.0 | 5650.0 |
| BSCL2 | 4891.0 | -4593.0 |
| BTG2 | 6071.0 | 6308.0 |
| C11orf95 | -1807.0 | -875.0 |
| C3AR1 | -1253.0 | 7488.0 |
| CCDC106 | 3305.0 | -3283.0 |
| CCL2 | -1079.0 | 3167.0 |
| CCNA2 | 4669.0 | 307.0 |
| CCNB2 | 5920.0 | -1519.0 |
| CCR1 | -3507.0 | 4981.0 |
| CCR7 | -4606.0 | -4191.0 |
| CCRL2 | -518.0 | 4774.0 |
| CD3EAP | 3522.0 | 2248.0 |
| CDC20 | 6493.0 | -3052.0 |
| CDH17 | -1983.0 | -292.0 |
| CDK14 | -2632.0 | 8039.0 |
| CDK9 | 315.0 | -5322.0 |
| CEACAM4 | 463.5 | -6623.5 |
| CELSR1 | 8016.0 | -4778.0 |
| CHM | -4490.0 | 8464.0 |
| CHTOP | -4615.0 | -1316.0 |
| CISH | -419.0 | -2121.0 |
| CKAP2 | 6527.0 | -3445.0 |
| COCH | -2313.0 | 1069.0 |
| CORO1A | -3183.0 | -17.0 |
| CPT1A | 5912.0 | -394.0 |
| CR2 | -2478.0 | 2360.0 |
| CSNK1D | -1602.0 | 2506.0 |
| CWC25 | 1034.0 | 5526.0 |
| CXCR2 | -4298.0 | 3063.0 |
| CYP4F3 | 9.0 | 6130.0 |
| DBR1 | 985.0 | 3157.0 |
| DHX32 | -759.0 | 5873.0 |
| DNAAF5 | 7068.0 | -1825.0 |
| DNAJC11 | 4115.0 | 1856.0 |
| DUSP6 | -5078.0 | 6412.0 |
| EGLN1 | -4261.5 | -1804.5 |
| EGR1 | 1105.0 | 4313.0 |
| EGR2 | -1617.0 | 4130.0 |
| EGR3 | -3140.0 | 2625.0 |
| EHD1 | -5018.0 | 2286.0 |
| ELF1 | -3303.0 | 7541.0 |
| ELL2 | -4455.0 | 7755.0 |
| EZH2 | 13.0 | 1789.0 |
| F2RL1 | 7281.0 | 4283.0 |
| FOLR3 | 4808.5 | -5490.5 |
| FOSB | 6048.0 | -74.0 |
| FRAT2 | 5931.0 | -4034.0 |
| G0S2 | 4904.0 | 8051.0 |
| GAR1 | 642.0 | -352.0 |
| GIGYF2 | -6140.0 | -70.0 |
| HEPH | -3944.0 | 6444.0 |
| HLX | -778.0 | 6383.0 |
| IER2 | 6951.0 | -524.0 |
| IGF2R | 7820.0 | -602.0 |
| IGKC | -2925.0 | 7318.0 |
| IL1B | -6242.0 | 3978.0 |
| IL1R2 | -2817.0 | 6793.0 |
| INPP5D | -1230.0 | 5535.0 |
| IRF4 | -1439.0 | -700.0 |
| IVNS1ABP | 7265.0 | 1321.0 |
| KCNJ15 | -5752.0 | 2831.0 |
| KIAA0040 | 23.0 | 6781.0 |
| KIAA0319 | 1289.0 | -5453.0 |
| KRT23 | -660.0 | 3043.0 |
| LCMT2 | -6209.0 | -5817.0 |
| LDB1 | 7924.0 | 2101.0 |
| LIG1 | 4884.0 | 892.0 |
| LIMK2 | 7085.0 | -848.0 |
| LMTK2 | -5556.0 | -964.0 |
| MAFB | 8140.0 | 2473.0 |
| MANSC1 | 7247.0 | 3029.0 |
| MAP3K20 | 8060.0 | 6853.0 |
| MAU2 | 4263.0 | -5182.0 |
| MCL1 | 6260.0 | -1020.0 |
| MCM3 | 3095.0 | 7219.0 |
| MCRS1 | 3404.0 | 504.0 |
| MEFV | -4277.0 | 5186.0 |
| MGAM | 561.0 | 417.0 |
| MKLN1 | 582.0 | 3529.0 |
| MME | -2831.0 | 3783.0 |
| MRAS | 6507.0 | 4369.0 |
| MYC | 1892.0 | 3123.0 |
| MYNN | -1936.0 | 5744.0 |
| MZB1 | 2359.0 | -2500.0 |
| NAMPT | 8078.0 | 8082.0 |
| NCAPG | 3536.0 | 1273.0 |
| NCF4 | -5987.0 | 5579.0 |
| NDEL1 | 206.0 | 1834.0 |
| NFYA | -6056.0 | 1269.0 |
| NRBF2 | -6534.0 | 8395.0 |
| NUTF2 | -2549.0 | 1665.0 |
| OLFM4 | 6940.0 | -1244.0 |
| OSBPL2 | 388.0 | 6106.0 |
| OSTF1 | 6553.0 | 5854.0 |
| PADI2 | -2608.0 | -2165.0 |
| PARM1 | -435.0 | 5897.0 |
| PCBP4 | 5524.0 | -5626.0 |
| PDCD6 | 2803.0 | 5419.0 |
| PDCL | -1384.0 | 7789.0 |
| PDK4 | 3864.0 | 4092.0 |
| PIK3CB | -1756.0 | 1880.0 |
| PIM1 | -3615.0 | 5315.0 |
| PNP | -7335.0 | 8459.0 |
| PPP1R10 | 4037.0 | -3570.0 |
| PTGS2 | -2970.0 | 5783.0 |
| PTPN21 | 2719.0 | -4215.0 |
| PTPRE | 3132.0 | 1553.0 |
| PYCR3 | -6318.0 | 2115.0 |
| RCL1 | 5218.0 | 4620.0 |
| RGCC | 7096.0 | 3390.0 |
| RGS2 | 3150.0 | 1108.0 |
| RRAGA | -3310.0 | 5815.0 |
| S100A8 | -3981.0 | 6893.0 |
| S1PR1 | 4311.0 | 7637.0 |
| SELL | -4022.0 | 902.0 |
| SEMA4D | -573.0 | -5740.0 |
| SGK1 | 4488.0 | 7322.0 |
| SLC19A1 | 4798.0 | -4123.0 |
| SLC25A20 | 6499.0 | 4961.0 |
| SLPI | 307.0 | 3136.0 |
| SNX19 | 15.0 | 855.0 |
| SOCS3 | 4231.0 | 7185.0 |
| SPAG8 | 2548.0 | -5221.0 |
| SPATA2L | 2799.0 | -4361.0 |
| ST14 | 7899.0 | 2632.0 |
| ST8SIA4 | -6249.0 | 6735.0 |
| STEAP4 | 4260.0 | 7386.0 |
| SVIL | -3260.0 | -6020.0 |
| TBC1D9 | 3187.0 | 4014.0 |
| THBD | -6500.0 | 7788.0 |
| THRAP3 | 6727.0 | 760.0 |
| TLR1 | -3224.0 | 560.0 |
| TLR6 | -4778.0 | 7142.0 |
| TMEM185B | -4851.0 | -3834.0 |
| TNFAIP6 | -3592.0 | 4376.0 |
| TRAF3 | -6416.0 | 5442.0 |
| TREM1 | 169.0 | -2242.0 |
| TREML2 | -3185.0 | 3037.0 |
| TRIB1 | 7573.0 | 2586.0 |
| UBAP1 | -6158.0 | 7653.0 |
| USP20 | -4736.0 | -5752.0 |
| WDR3 | -6076.0 | 2575.0 |
| WIPI2 | -3357.0 | -5676.0 |
| ZFP30 | -521.0 | -3488.0 |
| ZFP36 | -1295.0 | 1383.0 |
| ZHX2 | -7088.0 | 76.0 |
| ZNF654 | -1490.0 | 8187.0 |
WP_TYPE_II_DIABETES_MELLITUS
| metric | value |
|---|---|
| setSize | 20 |
| pMANOVA | 0.62 |
| p.adjustMANOVA | 0.74 |
| s.dist | 0.122 |
| s.diabetes | -0.00833 |
| s.mitoG | -0.121 |
| p.diabetes | 0.949 |
| p.mitoG | 0.347 |
| Gene | diabetes | mitoG |
|---|---|---|
| PRKCZ | -2030 | -5814 |
| IKBKB | -1785 | -5829 |
| MTOR | -4145 | -2344 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| ADIPOQ | 3018.0 | -3550.0 |
| CACNA1A | 1894.0 | -3861.0 |
| GK | -4767.5 | 4354.5 |
| IKBKB | -1785.0 | -5829.0 |
| INSR | 3417.0 | 173.0 |
| IRS1 | 7064.0 | -5549.0 |
| KCNJ11 | 2961.0 | -3265.0 |
| MAFA | -3053.0 | 2846.0 |
| MAPK1 | -3928.0 | 6920.0 |
| MAPK8 | -3252.0 | 1695.0 |
| MTOR | -4145.0 | -2344.0 |
| PHKA2 | 5251.0 | -5498.0 |
| PIK3R5 | -1994.0 | 2879.0 |
| PRKCD | 365.0 | 1901.0 |
| PRKCZ | -2030.0 | -5814.0 |
| SLC2A2 | 7902.0 | 2301.0 |
| SLC2A4 | 8055.0 | -2624.0 |
| SOCS4 | -6470.0 | 7880.0 |
| SURF1 | 2134.0 | 4131.0 |
| TNF | -2778.0 | 4883.0 |
HP_TYPE_II_DIABETES_MELLITUS
| metric | value |
|---|---|
| setSize | 139 |
| pMANOVA | 0.0792 |
| p.adjustMANOVA | 0.117 |
| s.dist | 0.12 |
| s.diabetes | 0.104 |
| s.mitoG | -0.059 |
| p.diabetes | 0.0342 |
| p.mitoG | 0.231 |
| Gene | diabetes | mitoG |
|---|---|---|
| HNF1A | 7450.0 | -6675.0 |
| SPINK1 | 7315.0 | -6310.0 |
| PCNT | 7772.0 | -5691.0 |
| IRS1 | 7064.0 | -5549.0 |
| ZNF513 | 5138.0 | -5859.0 |
| SEMA4A | 4531.0 | -6239.0 |
| SLC12A3 | 6051.0 | -4654.0 |
| WFS1 | 7688.0 | -3009.0 |
| IFT172 | 3902.0 | -5651.0 |
| USH2A | 4128.0 | -4852.0 |
| MKRN3 | 3610.0 | -5497.0 |
| LMNA | 5092.0 | -3667.0 |
| CERKL | 2847.0 | -6517.0 |
| PEX10 | 4740.0 | -3790.0 |
| CRX | 3115.0 | -5642.0 |
| CLCNKB | 8258.5 | -2053.5 |
| ELN | 3735.0 | -4141.0 |
| ATM | 5701.0 | -2536.0 |
| BBS2 | 4288.0 | -2928.0 |
| AGBL5 | 1997.0 | -5951.0 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| ABCA4 | 277.0 | -4736.0 |
| AGBL5 | 1997.0 | -5951.0 |
| AHI1 | 5934.0 | 682.0 |
| AHR | 2185.5 | 5110.5 |
| AIP | -549.0 | 3479.0 |
| AKT2 | -4939.0 | 3281.0 |
| ALMS1 | 1616.0 | -638.0 |
| AMACR | -7290.0 | -2238.0 |
| AR | 2841.0 | 2349.0 |
| ARHGEF18 | 5858.5 | -119.5 |
| ARL2BP | 6697.0 | 5530.0 |
| ARL3 | 4427.0 | 1315.0 |
| ARL6 | -1042.0 | 6323.0 |
| ATM | 5701.0 | -2536.0 |
| BAZ1B | -6161.0 | 79.0 |
| BBS2 | 4288.0 | -2928.0 |
| BEST1 | -4777.0 | 1784.0 |
| BLM | 6861.0 | 5650.0 |
| BRAF | -6284.0 | 4955.0 |
| C8orf37 | -2986.0 | 5151.0 |
| CA4 | -6448.0 | 2608.0 |
| CAT | -602.0 | 4907.0 |
| CEP19 | -4989.0 | 5512.0 |
| CERKL | 2847.0 | -6517.0 |
| CLCNKB | 8258.5 | -2053.5 |
| CLIP2 | -4217.0 | -5731.0 |
| CLRN1 | 3080.0 | -2656.0 |
| CNGB1 | -1532.0 | 170.0 |
| CRB1 | -4803.0 | -4998.0 |
| CRX | 3115.0 | -5642.0 |
| CTNNB1 | -6022.0 | 2664.0 |
| DHDDS | -4632.0 | -1973.0 |
| DHX38 | 3912.0 | -1919.0 |
| DMXL2 | 5807.0 | 1760.0 |
| ELN | 3735.0 | -4141.0 |
| ENPP1 | -4115.0 | 6101.0 |
| FAM161A | 7876.0 | -973.0 |
| FBN1 | 6578.0 | 8391.0 |
| FSCN2 | 3414.0 | -1787.0 |
| GLRX5 | 6724.0 | 4490.0 |
| GPD2 | -5845.0 | 8339.0 |
| GTF2I | -3516.0 | -4858.0 |
| GTF2IRD1 | 3674.0 | 2580.0 |
| GUCA1B | -1248.0 | -1221.0 |
| HERC2 | -123.0 | -4460.0 |
| HGSNAT | 6373.0 | 2744.0 |
| HMGA1 | 7803.0 | -1488.0 |
| HNF1A | 7450.0 | -6675.0 |
| HNF1B | -1771.0 | -6141.0 |
| HNF4A | -6855.0 | 4619.0 |
| IDH3A | -958.0 | 7080.0 |
| IDH3B | 3081.0 | 573.0 |
| IFT140 | 1480.0 | -4541.0 |
| IFT172 | 3902.0 | -5651.0 |
| IFT88 | -4968.0 | 4229.0 |
| IGF2BP2 | 1777.0 | 3236.0 |
| IMPDH1 | 1190.0 | 4821.0 |
| IMPG2 | 226.0 | -3197.0 |
| INSR | 3417.0 | 173.0 |
| IRS1 | 7064.0 | -5549.0 |
| IRS2 | -582.0 | 3045.0 |
| KCNJ11 | 2961.0 | -3265.0 |
| KIAA1549 | 2144.0 | -3229.0 |
| KIZ | 1104.0 | 4332.0 |
| KLF11 | 7284.0 | 1719.0 |
| KLHL7 | 68.0 | 5321.0 |
| LIG4 | -3349.0 | 7573.0 |
| LIMK1 | 3519.0 | 2264.0 |
| LMNA | 5092.0 | -3667.0 |
| LRAT | -1726.0 | 2615.0 |
| MAK | -946.0 | -2629.0 |
| MAPK8IP1 | 7092.0 | 379.0 |
| MEN1 | -1596.0 | -513.0 |
| MERTK | 2880.0 | 6387.0 |
| MKRN3 | 3610.0 | -5497.0 |
| MT-CO1 | 6781.0 | 5983.0 |
| MT-CO2 | 293.0 | -1711.0 |
| MT-CO3 | 2273.0 | 6269.0 |
| MT-ND1 | 5618.0 | 7323.0 |
| MT-ND4 | 1752.0 | 7883.0 |
| MT-ND5 | 6025.0 | 8007.0 |
| MT-ND6 | 5059.0 | 8045.0 |
| NDN | 894.0 | 5072.0 |
| NEK2 | 2754.0 | -2383.0 |
| NRL | -2049.0 | -4885.0 |
| OFD1 | 5855.0 | 5805.0 |
| PCNT | 7772.0 | -5691.0 |
| PDE6A | -7253.0 | -877.0 |
| PDE6B | 1821.0 | -4534.0 |
| PDE6G | 1178.0 | -3727.0 |
| PEX10 | 4740.0 | -3790.0 |
| PLCD1 | 5021.0 | 2747.0 |
| PNPLA6 | -3845.0 | -5609.0 |
| POLA1 | -4288.0 | 598.0 |
| POLR3A | 5281.0 | -1328.0 |
| POMGNT1 | -1550.0 | 1400.0 |
| PPARG | -3636.0 | 5654.0 |
| PRCD | 476.0 | -2411.0 |
| PROM1 | 4188.0 | 1239.0 |
| PRPF3 | -4119.0 | 5240.0 |
| PRPF31 | -387.0 | 4117.0 |
| PRPF4 | -4040.0 | 1952.0 |
| PRPF6 | 3568.0 | 279.0 |
| PRPF8 | 947.0 | 5393.0 |
| PTPN1 | 6946.0 | 3039.0 |
| RDH12 | -3849.0 | 788.0 |
| REEP6 | 8248.0 | 6316.0 |
| RETN | -1704.0 | -1106.0 |
| RFC2 | -2310.0 | 1686.0 |
| RHO | 1583.0 | -5941.0 |
| ROM1 | 1249.0 | 206.0 |
| RP1 | -5651.0 | 2024.0 |
| RP2 | -6219.0 | 5609.0 |
| RP9 | 3230.0 | -898.0 |
| RPGR | 815.0 | -1281.0 |
| SAG | -299.0 | -4455.0 |
| SCAPER | 6106.0 | 3001.0 |
| SEMA4A | 4531.0 | -6239.0 |
| SLC12A3 | 6051.0 | -4654.0 |
| SLC2A2 | 7902.0 | 2301.0 |
| SLC30A8 | 3357.0 | -1419.0 |
| SLC7A14 | -129.0 | -4517.0 |
| SNRNP200 | -4151.0 | 749.0 |
| SNRPN | -4895.0 | 6816.0 |
| SPATA7 | 3517.0 | 1166.0 |
| SPINK1 | 7315.0 | -6310.0 |
| STUB1 | 4177.0 | -2823.0 |
| TBL2 | -4096.0 | 539.0 |
| TCF7L2 | -4057.0 | -2326.0 |
| TOPORS | 4771.0 | 6078.0 |
| TTC8 | -3401.0 | -592.0 |
| TUB | 1106.0 | -1287.0 |
| TULP1 | 3418.0 | 3237.0 |
| USH2A | 4128.0 | -4852.0 |
| WFS1 | 7688.0 | -3009.0 |
| WRN | 1837.0 | 6937.0 |
| XRCC4 | -4715.0 | 7026.0 |
| ZNF408 | 4726.0 | -545.0 |
| ZNF513 | 5138.0 | -5859.0 |
GSE9006_1MONTH_VS_4MONTH_POST_TYPE_1_DIABETES_DX_PBMC_UP
| metric | value |
|---|---|
| setSize | 167 |
| pMANOVA | 0.0288 |
| p.adjustMANOVA | 0.0561 |
| s.dist | 0.117 |
| s.diabetes | -0.00264 |
| s.mitoG | 0.117 |
| p.diabetes | 0.953 |
| p.mitoG | 0.00893 |
| Gene | diabetes | mitoG |
|---|---|---|
| TENT5A | -6948 | 8031 |
| ACOT9 | -5708 | 8538 |
| ATF4 | -6143 | 7857 |
| CTAGE1 | -5486 | 8570 |
| CPPED1 | -6207 | 6376 |
| DNAJC2 | -5076 | 7232 |
| KITLG | -4636 | 7908 |
| PLXNC1 | -5669 | 5576 |
| BCL2A1 | -5733 | 5402 |
| RBMS1 | -4349 | 7009 |
| DNAJC1 | -6576 | 4427 |
| DOCK2 | -5657 | 5085 |
| ZBP1 | -6151 | 4520 |
| CREM | -3568 | 7564 |
| COX16 | -3433 | 7416 |
| TFRC | -4827 | 4702 |
| FLRT3 | -4355 | 5017 |
| OR7E24 | -4864 | 4086 |
| PIM1 | -3615 | 5315 |
| IL1R2 | -2817 | 6793 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| AATF | 2607.0 | 2827.0 |
| ACOT9 | -5708.0 | 8538.0 |
| ADCK2 | -2442.0 | -5853.0 |
| ADGRA2 | 6742.0 | -4913.0 |
| ADM | 7469.0 | 6606.0 |
| AEN | 7917.0 | 1933.0 |
| ALOX5 | 5079.0 | -1468.0 |
| ANXA3 | 4126.0 | 8240.0 |
| AQP9 | -5382.0 | 1990.0 |
| ARHGAP26 | -7093.0 | 2682.0 |
| ARHGEF16 | 1946.0 | 1028.0 |
| ASPM | 3924.0 | -909.0 |
| ATF4 | -6143.0 | 7857.0 |
| ATG2A | 6419.0 | -6384.0 |
| B3GNT4 | 1421.0 | -968.0 |
| BCL2A1 | -5733.0 | 5402.0 |
| BCL6 | -4525.0 | 36.0 |
| BMP2 | 4300.0 | 7938.0 |
| CAMK2N1 | -5811.0 | 179.0 |
| CAPN3 | 3009.0 | -6323.0 |
| CARS2 | -4415.0 | -4360.0 |
| CBX6 | 3215.0 | -5159.0 |
| CCNJ | 4191.0 | -1046.0 |
| CD2BP2 | 5662.0 | -4064.0 |
| CD83 | -913.0 | 5700.0 |
| CEACAM8 | 3793.5 | 5357.5 |
| CHAF1A | 7526.0 | -1172.0 |
| COL8A2 | 1170.0 | 2569.0 |
| COX16 | -3433.0 | 7416.0 |
| CPPED1 | -6207.0 | 6376.0 |
| CREM | -3568.0 | 7564.0 |
| CRYBG3 | 5850.0 | 7100.0 |
| CTAGE1 | -5486.0 | 8570.0 |
| CTRL | 3393.0 | -4720.0 |
| CTSZ | -2861.0 | 2478.0 |
| CYP3A7 | 399.0 | 1822.0 |
| DHCR24 | -3812.0 | -2962.0 |
| DIP2A | 7923.0 | -2097.0 |
| DLX6 | -4732.0 | -216.0 |
| DNAJC1 | -6576.0 | 4427.0 |
| DNAJC2 | -5076.0 | 7232.0 |
| DOCK2 | -5657.0 | 5085.0 |
| DOCK5 | -5552.0 | -1658.0 |
| EFCAB11 | 1535.0 | -3457.0 |
| EGLN3 | 7904.0 | 4308.0 |
| EMILIN2 | -3487.0 | 2545.0 |
| ENC1 | 6176.0 | 4284.0 |
| EYA1 | -271.0 | 1524.0 |
| FAM13A | 7985.0 | 1055.0 |
| FIG4 | -2261.0 | 2661.0 |
| FLRT3 | -4355.0 | 5017.0 |
| FUT4 | 2474.0 | -2219.0 |
| GCNT4 | 7870.0 | 5943.0 |
| GMDS | 3172.0 | 2992.0 |
| GNG10 | 5845.0 | 2921.0 |
| GNG12 | -1212.0 | 6898.0 |
| GPC5 | -4977.0 | -3337.0 |
| GPR12 | -4047.0 | -1246.0 |
| GPR137B | -7258.0 | -935.0 |
| GRAMD1B | 919.0 | -2556.0 |
| GRAMD4 | -6920.0 | -604.0 |
| GUCY1A1 | 1918.0 | 7519.0 |
| HIC2 | 6652.0 | -6089.0 |
| HK3 | -4874.0 | 2139.0 |
| HLX | -778.0 | 6383.0 |
| ICAM4 | 997.0 | 2998.0 |
| IER3 | 2411.0 | 7011.0 |
| IFIT3 | 4120.0 | 6607.0 |
| IL1R2 | -2817.0 | 6793.0 |
| IL33 | 7328.0 | 7911.0 |
| IMPDH1 | 1190.0 | 4821.0 |
| INPP5A | 5585.0 | 6455.0 |
| IRF1 | 3086.0 | 3498.0 |
| KAZALD1 | -290.0 | 1843.0 |
| KBTBD11 | -5302.0 | -5124.0 |
| KIAA0232 | -2998.0 | 4724.0 |
| KITLG | -4636.0 | 7908.0 |
| KLF4 | 5830.0 | 7414.0 |
| KLHL36 | 2189.0 | -5945.0 |
| KPTN | 3882.0 | -3219.0 |
| LDLR | 4229.0 | 3193.0 |
| LETM1 | -2711.0 | 2319.0 |
| LIN7A | -84.0 | -4388.0 |
| LRRFIP2 | -2647.0 | 2384.0 |
| LUM | 4367.0 | 7749.0 |
| MAF | -4741.0 | -4090.0 |
| MAFF | 4078.0 | 3523.0 |
| MAP3K20 | 8060.0 | 6853.0 |
| MCUR1 | -1414.0 | 1795.0 |
| MGAM | 561.0 | 417.0 |
| MME | -2831.0 | 3783.0 |
| MNT | 3097.0 | -5444.0 |
| MRAS | 6507.0 | 4369.0 |
| MTARC2 | 7913.0 | 384.0 |
| MTF1 | -4371.0 | -3922.0 |
| MYBBP1A | 4445.0 | 965.0 |
| NADSYN1 | 6875.0 | -6478.0 |
| NAMPT | 8078.0 | 8082.0 |
| NECTIN3 | -6346.0 | 525.0 |
| NFKBIA | 1631.0 | 4830.0 |
| NFKBIE | -4334.0 | -123.0 |
| NID2 | -2779.0 | 3823.0 |
| NLRP3 | -5337.0 | 1863.0 |
| NOC2L | -4670.0 | 1010.0 |
| NPC2 | 3922.0 | 3679.0 |
| NUFIP1 | 4885.0 | 5778.0 |
| NUP93 | 5331.0 | 6196.0 |
| OBSL1 | -2821.0 | 4269.0 |
| OR7E24 | -4864.0 | 4086.0 |
| P2RY2 | 7810.0 | 1570.0 |
| PABPC1 | -949.0 | 6861.0 |
| PIGT | 2201.0 | -3364.0 |
| PIM1 | -3615.0 | 5315.0 |
| PLPPR4 | 6130.0 | 5171.0 |
| PLXNC1 | -5669.0 | 5576.0 |
| PRKD1 | -339.0 | 4350.0 |
| PTP4A1 | 6088.0 | 8315.0 |
| PTX3 | -4488.0 | -2545.0 |
| PYGL | 6729.0 | 1748.0 |
| R3HCC1 | 7667.0 | -1069.0 |
| RAP2C | -4441.0 | 2874.0 |
| RASSF9 | 2702.0 | 6648.0 |
| RBMS1 | -4349.0 | 7009.0 |
| RFX4 | 7908.0 | -2857.0 |
| RXRA | -5143.0 | 1552.0 |
| SAT1 | 5606.0 | 7029.0 |
| SCCPDH | 554.0 | -3193.0 |
| SCO2 | -3687.0 | 2948.0 |
| SERPINA1 | 8234.0 | 4905.0 |
| SGK1 | 4488.0 | 7322.0 |
| SLC19A1 | 4798.0 | -4123.0 |
| SLC22A4 | 6314.0 | -3631.0 |
| SLC30A9 | 2912.0 | 4119.0 |
| SLC39A9 | -4297.0 | -1684.0 |
| SMURF1 | 7065.0 | -1671.0 |
| SPRED2 | -1328.0 | -5582.0 |
| SPTLC2 | -735.0 | -2873.0 |
| SRGAP2 | -1169.0 | -688.0 |
| STX4 | -3184.0 | -4491.0 |
| SUSD5 | 2305.0 | 718.0 |
| TALDO1 | -5386.0 | 449.0 |
| TAS2R4 | 3211.0 | 545.0 |
| TAX1BP3 | 5769.0 | 6972.0 |
| TBC1D17 | 6335.0 | -6244.0 |
| TCIRG1 | -5363.0 | -3931.0 |
| TENT5A | -6948.0 | 8031.0 |
| TEX2 | -3123.0 | 4517.0 |
| TFRC | -4827.0 | 4702.0 |
| TIAL1 | -5851.0 | 3033.0 |
| TLR1 | -3224.0 | 560.0 |
| TMEM254 | -7257.0 | -5697.0 |
| TMEM255A | 3314.0 | 2481.0 |
| TNF | -2778.0 | 4883.0 |
| TNFAIP6 | -3592.0 | 4376.0 |
| TPMT | -2094.0 | 4118.0 |
| TRDN | -6980.0 | 2227.0 |
| TRIB1 | 7573.0 | 2586.0 |
| TRIL | -3580.0 | 4278.0 |
| TSPAN9 | 4143.0 | 3244.0 |
| TYR | 1845.0 | -4177.0 |
| UPP1 | 5774.0 | 8231.0 |
| USP13 | -642.0 | 3525.0 |
| WWP2 | 5708.0 | -972.0 |
| ZBP1 | -6151.0 | 4520.0 |
| ZNF280B | -4822.0 | 3198.0 |
| ZNF287 | 2256.0 | 2713.0 |
| ZNF394 | 73.0 | -278.0 |
GSE9006_TYPE_1_DIABETES_AT_DX_VS_4MONTH_POST_DX_PBMC_UP
| metric | value |
|---|---|
| setSize | 182 |
| pMANOVA | 0.0487 |
| p.adjustMANOVA | 0.0858 |
| s.dist | 0.105 |
| s.diabetes | -0.00885 |
| s.mitoG | 0.105 |
| p.diabetes | 0.837 |
| p.mitoG | 0.0148 |
| Gene | diabetes | mitoG |
|---|---|---|
| HNRNPA3 | -6985 | 8827 |
| PDIA3 | -7283 | 7821 |
| PDIA4 | -7329 | 7729 |
| HSPA5 | -7309 | 7589 |
| RPN1 | -7121 | 7464 |
| YWHAZ | -5614 | 8512 |
| NSD1 | -6917 | 6189 |
| GMPS | -5160 | 8238 |
| KDELR2 | -4969 | 8520 |
| ARL4A | -6095 | 6821 |
| ACTR2 | -5189 | 7356 |
| HNRNPU | -5219 | 7082 |
| P4HB | -6743 | 5398 |
| NFIL3 | -7012 | 5060 |
| PAK2 | -4906 | 6708 |
| GNAI3 | -3916 | 8277 |
| HNRNPH2 | -5391 | 5932 |
| MAPRE1 | -3633 | 8509 |
| PTPRA | -5907 | 5079 |
| CYBB | -5520 | 5307 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| AAMP | 69.0 | -4287.0 |
| ACTR2 | -5189.0 | 7356.0 |
| ADM | 7469.0 | 6606.0 |
| ADNP2 | 2146.0 | 595.0 |
| ALDOA | 6979.5 | 3652.5 |
| AMDHD2 | -5012.5 | -6718.5 |
| APOBR | -726.0 | -1447.0 |
| AQP9 | -5382.0 | 1990.0 |
| ARF6 | -804.0 | 229.0 |
| ARHGAP26 | -7093.0 | 2682.0 |
| ARL4A | -6095.0 | 6821.0 |
| ATP6V0A1 | 936.0 | 1549.0 |
| ATP6V0D1 | -3890.0 | 3817.0 |
| BAG5 | -2637.0 | 8168.0 |
| BCL6 | -4525.0 | 36.0 |
| BHLHE40 | -185.0 | 1804.0 |
| BNIP2 | 3400.0 | 6267.0 |
| CARS2 | -4415.0 | -4360.0 |
| CCDC22 | -4166.0 | -3221.0 |
| CD83 | -913.0 | 5700.0 |
| CDC37 | -682.0 | -4414.0 |
| CDK9 | 315.0 | -5322.0 |
| CDT1 | 6848.0 | -4131.0 |
| CEACAM8 | 3793.5 | 5357.5 |
| CHFR | 686.0 | 5588.0 |
| CIRBP | 8197.0 | -922.0 |
| CKAP4 | 4629.0 | 6520.0 |
| COPG1 | -3891.0 | 3599.0 |
| COPS7B | -2394.0 | -5916.0 |
| COTL1 | 8183.0 | -5409.0 |
| CREM | -3568.0 | 7564.0 |
| CTSD | 5035.5 | 6716.5 |
| CTSZ | -2861.0 | 2478.0 |
| CXCR4 | 4516.0 | 7547.0 |
| CYBB | -5520.0 | 5307.0 |
| DDIT4 | 5684.0 | 4879.0 |
| DDX3X | 3775.0 | 8058.0 |
| DHCR7 | 3894.0 | -5672.0 |
| DUSP1 | -2905.0 | -1666.0 |
| DUSP5 | 4923.0 | 4971.0 |
| EGR3 | -3140.0 | 2625.0 |
| EHD4 | 5130.0 | 8802.0 |
| EIF4ENIF1 | -1402.0 | 4499.0 |
| ELMO1 | -4833.0 | 4917.0 |
| FOSB | 6048.0 | -74.0 |
| FZR1 | 3996.0 | -5000.0 |
| G0S2 | 4904.0 | 8051.0 |
| G3BP2 | -4462.0 | 5928.0 |
| GLG1 | -3103.0 | 2134.0 |
| GLUD1 | 8064.5 | 3730.5 |
| GLUL | 7900.0 | 3064.0 |
| GMPS | -5160.0 | 8238.0 |
| GNAI3 | -3916.0 | 8277.0 |
| GPAA1 | 696.0 | -5319.0 |
| GPI | 4816.0 | 5422.0 |
| GSN | 7535.0 | 7997.0 |
| GUSB | -7203.0 | 1338.0 |
| HBEGF | -6694.0 | -80.0 |
| HERPUD1 | 924.0 | 3108.0 |
| HMGB2 | 6857.0 | 1304.0 |
| HNRNPA1 | 7891.0 | -6290.0 |
| HNRNPA3 | -6985.0 | 8827.0 |
| HNRNPH2 | -5391.0 | 5932.0 |
| HNRNPK | -808.0 | 7246.0 |
| HNRNPU | -5219.0 | 7082.0 |
| HP | -1369.5 | 6104.5 |
| HSPA5 | -7309.0 | 7589.0 |
| HSPA9 | -566.0 | 8181.0 |
| HYOU1 | -7255.0 | 4009.0 |
| IBTK | -3540.0 | 7124.0 |
| ID1 | 3953.0 | -1529.0 |
| IER2 | 6951.0 | -524.0 |
| IL1B | -6242.0 | 3978.0 |
| IL1R1 | 3443.0 | 7288.0 |
| ILVBL | 3004.0 | -6442.0 |
| IVNS1ABP | 7265.0 | 1321.0 |
| JUNB | 4544.0 | 2430.0 |
| JUND | 4819.0 | -5317.0 |
| KDELR2 | -4969.0 | 8520.0 |
| KIAA0930 | 4163.0 | -2258.0 |
| LAPTM5 | -5721.0 | 4643.0 |
| LSM12 | -2869.0 | 4929.0 |
| MAFB | 8140.0 | 2473.0 |
| MAPK1IP1L | 345.0 | -2618.0 |
| MAPRE1 | -3633.0 | 8509.0 |
| MARCKS | -1781.0 | 5038.0 |
| MCL1 | 6260.0 | -1020.0 |
| MFSD10 | 6323.0 | -5202.0 |
| MGAM | 561.0 | 417.0 |
| MINK1 | -4877.0 | -2450.0 |
| MRPL12 | -2913.0 | 4144.0 |
| NADSYN1 | 6875.0 | -6478.0 |
| NAMPT | 8078.0 | 8082.0 |
| NDUFV1 | 4313.0 | -2431.0 |
| NECAP1 | -79.0 | 5214.0 |
| NFIL3 | -7012.0 | 5060.0 |
| NFKB2 | 2120.0 | -4751.0 |
| NFKBIA | 1631.0 | 4830.0 |
| NOC2L | -4670.0 | 1010.0 |
| NPTN | 2459.0 | 6839.0 |
| NR4A2 | -168.0 | 5972.0 |
| NSD1 | -6917.0 | 6189.0 |
| NUDT18 | 1357.0 | -3593.0 |
| NUP93 | 5331.0 | 6196.0 |
| ODF2 | 8196.0 | -5679.0 |
| P2RY2 | 7810.0 | 1570.0 |
| P4HB | -6743.0 | 5398.0 |
| PABPC4 | 2846.0 | -3784.0 |
| PAF1 | 799.0 | 4723.0 |
| PAK2 | -4906.0 | 6708.0 |
| PDIA3 | -7283.0 | 7821.0 |
| PDIA4 | -7329.0 | 7729.0 |
| PFKFB3 | 7737.0 | 7129.0 |
| PHF21A | -2368.0 | 829.0 |
| PIGA | 5537.0 | -3293.0 |
| PLEKHO2 | -1522.5 | 7084.5 |
| PLK3 | 4741.0 | 6581.0 |
| PPIF | 6302.0 | -1305.0 |
| PPP1R15A | 7471.0 | 4761.0 |
| PPP4C | 851.0 | -5414.0 |
| PRCC | -3064.0 | -3244.0 |
| PRMT7 | 5794.0 | 1791.0 |
| PRPF6 | 3568.0 | 279.0 |
| PSMD13 | 1898.0 | 5044.0 |
| PTPRA | -5907.0 | 5079.0 |
| PTX3 | -4488.0 | -2545.0 |
| PUF60 | -754.0 | 731.0 |
| QSOX1 | 7456.0 | 1100.0 |
| RAB1B | -80.0 | -4574.0 |
| RAB8A | -855.0 | 2596.0 |
| RBM3 | 8175.0 | 5192.0 |
| RETREG2 | -3830.0 | -5500.0 |
| REX1BD | 1924.0 | -3848.0 |
| RGS1 | -2963.0 | 3569.0 |
| RNF19B | -3119.0 | -1959.0 |
| RPN1 | -7121.0 | 7464.0 |
| RRP12 | 3149.0 | 2306.0 |
| RTN3 | -2760.0 | 5623.0 |
| SAFB | -1933.0 | -1132.0 |
| SAFB2 | 3321.0 | -6673.0 |
| SART1 | 2632.0 | -1920.0 |
| SAT1 | 5606.0 | 7029.0 |
| SCO2 | -3687.0 | 2948.0 |
| SCPEP1 | 4057.0 | 1287.0 |
| SFN | 3916.0 | 5704.0 |
| SFPQ | -5196.0 | -4828.0 |
| SGK1 | 4488.0 | 7322.0 |
| SGTA | 1239.0 | -1672.0 |
| SIK1 | 3616.5 | 666.5 |
| SIL1 | -5762.0 | 4185.0 |
| SLC30A9 | 2912.0 | 4119.0 |
| SNF8 | 2397.0 | -3270.0 |
| SOCS1 | -253.0 | -5520.0 |
| SOCS3 | 4231.0 | 7185.0 |
| SPATA2L | 2799.0 | -4361.0 |
| SRSF9 | -2009.0 | -5029.0 |
| STX11 | 608.0 | -2244.0 |
| TCIRG1 | -5363.0 | -3931.0 |
| TESK2 | 2566.0 | -4280.0 |
| THOC6 | -3723.0 | -3958.0 |
| TNFAIP3 | -151.0 | 2986.0 |
| TNFRSF14 | 872.0 | -1648.0 |
| TP53BP2 | 6638.0 | 5316.0 |
| TPD52L2 | 95.0 | 3488.0 |
| TREM1 | 169.0 | -2242.0 |
| TRIB1 | 7573.0 | 2586.0 |
| TSC22D3 | 1663.0 | 5520.0 |
| TSPAN14 | -6627.0 | 1158.0 |
| TSR3 | 4228.0 | -5856.0 |
| TYMP | 5612.0 | -6441.0 |
| UAP1 | -7245.0 | 1255.0 |
| UPP1 | 5774.0 | 8231.0 |
| UQCRC1 | 5627.0 | 1729.0 |
| VASP | -2568.0 | 4503.0 |
| WDR18 | -5000.0 | -3150.0 |
| WDR70 | -2702.0 | 2639.0 |
| WIPI2 | -3357.0 | -5676.0 |
| YWHAZ | -5614.0 | 8512.0 |
| ZBTB17 | 2405.0 | -590.0 |
| ZFP36 | -1295.0 | 1383.0 |
| ZFP36L1 | -5993.0 | 4405.0 |
| ZNF394 | 73.0 | -278.0 |
GSE40225_WT_VS_RIP_B7X_DIABETIC_MOUSE_PANCREATIC_CD8_TCELL_UP
| metric | value |
|---|---|
| setSize | 169 |
| pMANOVA | 0.103 |
| p.adjustMANOVA | 0.146 |
| s.dist | 0.104 |
| s.diabetes | -0.0849 |
| s.mitoG | 0.0603 |
| p.diabetes | 0.0573 |
| p.mitoG | 0.177 |
| Gene | diabetes | mitoG |
|---|---|---|
| CHPT1 | -6923 | 8136 |
| PSIP1 | -6597 | 7229 |
| CLCN4 | -6858 | 6649 |
| TRIM44 | -6012 | 7523 |
| RASA1 | -5274 | 8011 |
| MACF1 | -5316 | 7849 |
| KANSL1L | -7157 | 5803 |
| SLA | -5684 | 7023 |
| MSL2 | -6222 | 6310 |
| FLT1 | -4346 | 8420 |
| ZNRF2 | -7152 | 5062 |
| PUM2 | -6583 | 5351 |
| TLK1 | -4064 | 8347 |
| DTX4 | -6400 | 5051 |
| SEMA3D | -4476 | 7110 |
| CHIC1 | -6180 | 5139 |
| BRAF | -6284 | 4955 |
| KDM1B | -5262 | 5818 |
| VEZF1 | -3497 | 8422 |
| CYBB | -5520 | 5307 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| ABCC5 | 4476.0 | -5612.0 |
| ABL2 | -4140.0 | 5490.0 |
| ADAM28 | -400.0 | -2844.0 |
| AGBL2 | 843.0 | -1917.0 |
| AIDA | 3668.0 | 8141.0 |
| AMPD3 | 7453.0 | 2602.0 |
| ANKRD44 | 4522.0 | 3975.0 |
| AP4S1 | 2217.0 | 1812.0 |
| APLP2 | 6384.0 | 6357.0 |
| ATAD2B | -6031.0 | 4819.0 |
| ATP6V1H | -1095.0 | 8501.0 |
| BACH2 | -1914.0 | -2696.0 |
| BMP2K | 3031.0 | 4459.0 |
| BRAF | -6284.0 | 4955.0 |
| CAMK1D | -4392.0 | 3073.0 |
| CCDC130 | 2887.0 | 2873.0 |
| CCNY | 1460.0 | 6289.0 |
| CD1D | 5611.0 | 119.0 |
| CD79B | -2701.0 | 2433.0 |
| CDK5R1 | 4903.0 | -6336.0 |
| CDKL1 | -4030.0 | -2983.0 |
| CELF1 | -3196.0 | 4473.0 |
| CHD7 | 6375.0 | 5995.0 |
| CHIC1 | -6180.0 | 5139.0 |
| CHL1 | -6480.0 | -3081.0 |
| CHPT1 | -6923.0 | 8136.0 |
| CLCF1 | 6318.0 | -5706.0 |
| CLCN4 | -6858.0 | 6649.0 |
| COLGALT1 | 6399.0 | 362.0 |
| CRIP3 | -302.0 | -4109.0 |
| CTNND1 | 5833.0 | 1565.0 |
| CYBB | -5520.0 | 5307.0 |
| CYP2U1 | 4939.0 | 30.0 |
| DDX39B | 4289.0 | -5871.0 |
| DEAF1 | 7709.0 | -5938.0 |
| DENND4C | -5667.0 | 856.0 |
| DISP1 | 1277.0 | -673.0 |
| DOCK11 | -5090.0 | 5477.0 |
| DOCK2 | -5657.0 | 5085.0 |
| DTX1 | -4241.0 | -1078.0 |
| DTX4 | -6400.0 | 5051.0 |
| DZIP3 | -3939.0 | -4126.0 |
| ENPP1 | -4115.0 | 6101.0 |
| EPG5 | 4477.0 | -3271.0 |
| ESD | 771.0 | 8516.0 |
| ETS1 | -599.0 | 8648.0 |
| EVL | -186.0 | 264.0 |
| EXOC2 | 7117.0 | -1912.0 |
| FBXO11 | -2703.0 | 8171.0 |
| FCHSD2 | -4459.0 | 4958.0 |
| FCMR | 908.0 | 2646.0 |
| FCRLA | -3221.0 | 4407.0 |
| FLT1 | -4346.0 | 8420.0 |
| FMNL3 | 4975.0 | 5690.0 |
| GALNT7 | -5139.0 | 1034.0 |
| GSAP | -7019.0 | -4275.0 |
| HNRNPA1 | 7891.0 | -6290.0 |
| IFNGR2 | 4633.0 | 5019.0 |
| IL4R | 647.0 | 5708.0 |
| INPP5D | -1230.0 | 5535.0 |
| JADE2 | 7429.0 | -5745.0 |
| JAK3 | 7556.0 | -6301.0 |
| KANSL1L | -7157.0 | 5803.0 |
| KCNG1 | -4013.0 | -2822.0 |
| KDM1B | -5262.0 | 5818.0 |
| KHDRBS2 | -5128.0 | -5318.0 |
| KLF16 | 6650.0 | -5119.0 |
| KLHL36 | 2189.0 | -5945.0 |
| KMT5B | -2983.0 | -2250.0 |
| LARS1 | 7823.0 | -1599.0 |
| LAT2 | -2578.0 | 2305.0 |
| LIPA | 5735.0 | -3962.0 |
| LPGAT1 | -6932.0 | -124.0 |
| LRRC56 | 2735.0 | -5366.0 |
| MACF1 | -5316.0 | 7849.0 |
| MID1IP1 | -3383.0 | 5984.0 |
| MSL2 | -6222.0 | 6310.0 |
| NR3C2 | 7008.0 | -3900.0 |
| NSD3 | -2348.0 | -5726.0 |
| NUDCD3 | 4876.0 | -1297.0 |
| NUMA1 | 461.0 | -2761.0 |
| OBI1 | -2332.0 | 4483.0 |
| OGA | -3220.0 | 3703.0 |
| OSTF1 | 6553.0 | 5854.0 |
| PARP12 | 3615.0 | -4394.0 |
| PARP14 | -5054.0 | 4222.0 |
| PCNX2 | 17.0 | 2589.0 |
| PCSK7 | -3212.0 | -1627.0 |
| PDE8A | -3329.0 | 7592.0 |
| PHKA2 | 5251.0 | -5498.0 |
| PIK3C2B | 6591.0 | 344.0 |
| PLEKHF2 | -5672.0 | 4690.0 |
| PLSCR1 | -6591.0 | -6700.0 |
| POLM | 7521.0 | -6490.0 |
| PSIP1 | -6597.0 | 7229.0 |
| PTGS1 | 5729.0 | 6228.0 |
| PTPN6 | -1098.0 | 2140.0 |
| PUM1 | -856.0 | -3002.0 |
| PUM2 | -6583.0 | 5351.0 |
| RAB11FIP1 | 6379.0 | -3314.0 |
| RAB12 | -1057.0 | 8176.0 |
| RABGAP1 | -2389.0 | 6981.0 |
| RALGPS2 | -7239.0 | 156.0 |
| RASA1 | -5274.0 | 8011.0 |
| RASGRP2 | -326.0 | -409.0 |
| RB1 | 7982.0 | 7013.0 |
| RBM6 | -4932.0 | -3441.0 |
| RIPOR1 | 7727.0 | 791.0 |
| RNASEH2B | -3460.0 | 1126.0 |
| RNF130 | -2655.0 | 5163.0 |
| RNF216 | -840.0 | 5584.0 |
| RTN4IP1 | -2805.0 | -1723.0 |
| SAYSD1 | -1415.0 | -4296.0 |
| SCARNA6 | 7608.0 | -6503.0 |
| SELENON | 4701.5 | 6928.5 |
| SEMA3D | -4476.0 | 7110.0 |
| SENP7 | -4130.0 | -2819.0 |
| SESN3 | 7805.0 | 5009.0 |
| SGSM3 | 1120.0 | -6412.0 |
| SHPRH | -931.0 | 1674.0 |
| SIPA1L1 | -7292.0 | -118.0 |
| SLA | -5684.0 | 7023.0 |
| SLC2A1 | 6575.0 | 1160.0 |
| SLC30A4 | -608.0 | 7397.0 |
| SLC38A11 | 2988.0 | -3028.0 |
| SMC6 | 2636.0 | 7994.0 |
| SMG1 | -4496.0 | 2722.0 |
| SNORA14B | -2282.5 | 1679.5 |
| SNRK | 5854.0 | 6577.0 |
| SNX10 | -183.0 | 2964.0 |
| SNX27 | -6914.0 | -508.0 |
| SORL1 | 6003.0 | -3663.0 |
| SP4 | 7612.0 | 4668.0 |
| ST3GAL1 | 3065.0 | 8669.0 |
| ST3GAL3 | -3090.0 | 3648.0 |
| STAT5A | 2714.0 | -3795.0 |
| SUSD6 | 2969.0 | -594.0 |
| SWAP70 | 1447.0 | -519.0 |
| TANGO6 | -944.0 | -6105.0 |
| TBC1D10A | -3577.0 | -5886.0 |
| THADA | -2726.0 | -5996.0 |
| TLK1 | -4064.0 | 8347.0 |
| TMED8 | -4216.0 | 1979.0 |
| TRAK2 | 6380.0 | 7944.0 |
| TRIM44 | -6012.0 | 7523.0 |
| TRMT2B | -4410.0 | 3976.0 |
| TSC22D3 | 1663.0 | 5520.0 |
| TSPAN33 | 657.0 | -4997.0 |
| TTC13 | -5468.0 | 1837.0 |
| TTC21A | 4485.0 | 252.0 |
| TTC32 | -2659.0 | -209.0 |
| UBE2E2 | 2753.0 | 4580.0 |
| USF3 | -3481.0 | 3621.0 |
| USP44 | -3242.0 | 2971.0 |
| UTP25 | -910.0 | -3889.0 |
| VEZF1 | -3497.0 | 8422.0 |
| VPS13C | 8167.0 | -1191.0 |
| WDR5B | -3983.0 | 2770.0 |
| ZBTB10 | 2823.0 | 4913.0 |
| ZC3HAV1 | -469.0 | -613.0 |
| ZDHHC2 | -5398.0 | 353.0 |
| ZDHHC23 | 484.0 | -3279.0 |
| ZFYVE19 | 1682.0 | 4070.0 |
| ZFYVE27 | 5795.0 | -6615.0 |
| ZNF358 | 2745.0 | -1521.0 |
| ZNF557 | 1572.5 | 821.5 |
| ZNF678 | -1409.5 | 8810.5 |
| ZNRF2 | -7152.0 | 5062.0 |
| ZSCAN29 | -5275.0 | 3348.0 |
GSE9006_TYPE_1_DIABETES_AT_DX_VS_1MONTH_POST_DX_PBMC_DN
| metric | value |
|---|---|
| setSize | 165 |
| pMANOVA | 0.0705 |
| p.adjustMANOVA | 0.109 |
| s.dist | 0.0925 |
| s.diabetes | 0.0584 |
| s.mitoG | 0.0718 |
| p.diabetes | 0.196 |
| p.mitoG | 0.112 |
| Gene | diabetes | mitoG |
|---|---|---|
| CP | 7736 | 7894 |
| ATP2B4 | 7691 | 7255 |
| S100A10 | 7779 | 5985 |
| OSBPL1A | 6468 | 6678 |
| RGS5 | 5300 | 8040 |
| GSTO1 | 8023 | 4922 |
| TIMM8A | 4496 | 7741 |
| LUM | 4367 | 7749 |
| RUFY2 | 6866 | 4915 |
| ADAMTS5 | 4732 | 6838 |
| SMAD1 | 5880 | 5459 |
| RPL19 | 4654 | 6782 |
| BMPR1B | 5157 | 5691 |
| GMFG | 3969 | 7186 |
| MYL9 | 3189 | 8125 |
| RO60 | 3028 | 8186 |
| LPP | 7785 | 3122 |
| IFT46 | 5958 | 4026 |
| NOD1 | 5283 | 4068 |
| PFDN5 | 2482 | 8089 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| ABCC10 | 6808.0 | -6598.0 |
| ABITRAM | -1517.0 | 6842.0 |
| ADAMTS5 | 4732.0 | 6838.0 |
| ADGRA2 | 6742.0 | -4913.0 |
| ANXA2 | -337.0 | 8406.0 |
| APOO | -605.0 | 8803.0 |
| ARMCX4 | -5810.0 | 6643.0 |
| ARMH3 | 7270.0 | -3703.0 |
| ASRGL1 | 8192.0 | 1093.0 |
| ATAT1 | -6757.0 | -6199.0 |
| ATP2B4 | 7691.0 | 7255.0 |
| ATP5F1C | 164.0 | 8242.0 |
| ATXN3L | 633.5 | 4150.5 |
| BACE1 | 1099.0 | 3140.0 |
| BMPR1B | 5157.0 | 5691.0 |
| BRD3 | -2862.0 | -3037.0 |
| C1orf54 | 498.0 | -619.0 |
| C2orf68 | -4445.0 | -3173.0 |
| C3orf18 | 7780.0 | -4538.0 |
| CASR | -5215.0 | -1382.0 |
| CBFA2T2 | 1753.0 | 5677.0 |
| CCDC51 | 3605.0 | -4365.0 |
| CCDC71 | -4071.0 | 5182.0 |
| CCNF | 4264.0 | -2470.0 |
| CCNI | 265.0 | 6150.0 |
| CCNT1 | -709.0 | 6941.0 |
| CCSER2 | -6272.0 | 3686.0 |
| CDKN2C | 6608.0 | -3067.0 |
| CLEC1A | 1450.0 | 6546.0 |
| CLOCK | -7043.0 | 8412.0 |
| COA4 | -3012.0 | 3241.0 |
| COMMD3 | -4289.0 | 8822.0 |
| COQ6 | 1950.0 | -3453.0 |
| COX4I1 | 6324.0 | -2473.0 |
| CP | 7736.0 | 7894.0 |
| CXorf56 | -5589.0 | 5814.0 |
| DAB2 | -5689.0 | 1606.0 |
| DARS2 | -5166.0 | 329.0 |
| DCTN2 | 2623.0 | -2017.0 |
| DNAJC1 | -6576.0 | 4427.0 |
| DNAJC28 | 3205.0 | 1021.0 |
| DPM3 | -20.0 | -5789.0 |
| DST | 1303.0 | 1938.0 |
| EIF2S2 | -3307.0 | 8799.0 |
| EIF5 | -1683.0 | 7276.0 |
| EIF5B | -1780.0 | 8616.0 |
| EPS15L1 | 3879.0 | -4887.0 |
| ESRP2 | 5000.0 | -3533.0 |
| F2 | -3087.0 | 4699.0 |
| FABP1 | 289.0 | -1810.0 |
| FAM111A | -3910.0 | 3549.0 |
| FIG4 | -2261.0 | 2661.0 |
| GFER | -6332.0 | 3685.0 |
| GFOD2 | 714.0 | -3471.0 |
| GLRA3 | 5145.0 | -5574.0 |
| GMFG | 3969.0 | 7186.0 |
| GPR171 | -4112.0 | 6669.0 |
| GRIA1 | 3840.0 | -983.0 |
| GSTO1 | 8023.0 | 4922.0 |
| GUCY1A1 | 1918.0 | 7519.0 |
| GUCY1B1 | -1671.0 | 7666.0 |
| HINT1 | 3946.0 | 413.0 |
| HOXA9 | 3263.0 | 751.0 |
| HSPA1L | -3778.0 | -133.0 |
| HSPB7 | 5741.0 | -1096.0 |
| IER3IP1 | -246.5 | -3466.5 |
| IFT46 | 5958.0 | 4026.0 |
| IGBP1 | -1717.5 | 4157.5 |
| ING4 | -4464.0 | -4099.0 |
| ITGB5 | 7359.0 | 1316.0 |
| KCNMA1 | 7158.0 | -4954.0 |
| KCNMB1 | 2084.0 | 6965.0 |
| KCNN3 | 244.0 | -1001.0 |
| KLF7 | -4593.0 | 8044.0 |
| LAMTOR5 | 4258.0 | 4393.0 |
| LIPE | 2527.0 | 415.0 |
| LPP | 7785.0 | 3122.0 |
| LRRC75B | -548.0 | -2539.0 |
| LUM | 4367.0 | 7749.0 |
| MAP3K19 | 380.0 | 543.0 |
| MC2R | 2425.0 | 5288.0 |
| MCCC1 | -5695.0 | 1708.0 |
| MDH1 | 4402.0 | 4491.0 |
| METTL9 | -553.0 | 7370.0 |
| MPV17 | -5777.0 | 4042.0 |
| MTHFD2L | 5275.0 | 1578.0 |
| MYL9 | 3189.0 | 8125.0 |
| NOD1 | 5283.0 | 4068.0 |
| NRCAM | 3619.0 | 5428.0 |
| OSBPL1A | 6468.0 | 6678.0 |
| OXA1L | 4609.0 | -4940.0 |
| PAFAH1B2 | -1657.0 | 7964.0 |
| PBLD | 2456.0 | -2483.0 |
| PCSK2 | -329.0 | -3823.0 |
| PDPK1 | -4074.0 | 1936.0 |
| PFDN5 | 2482.0 | 8089.0 |
| PHF11 | -7148.0 | 3818.0 |
| PIPOX | -966.0 | 1121.0 |
| PNPLA2 | 7942.0 | 833.0 |
| POLH | -295.0 | 1887.0 |
| PRELID3A | 496.0 | -5362.0 |
| PRRG4 | -1441.0 | 5729.0 |
| PTCRA | 4212.0 | -5168.0 |
| RABEPK | 2166.0 | 960.0 |
| RALGPS1 | 2494.0 | -5324.0 |
| RBMS1 | -4349.0 | 7009.0 |
| RBMX2 | 4443.0 | 3927.0 |
| RCAN2 | 1791.0 | 4781.0 |
| RGS5 | 5300.0 | 8040.0 |
| RHOBTB1 | -7181.0 | -4585.0 |
| RNF113A | -3023.0 | 3421.0 |
| RO60 | 3028.0 | 8186.0 |
| RPGR | 815.0 | -1281.0 |
| RPL12 | 6107.0 | -5604.0 |
| RPL14 | 5110.0 | -1875.0 |
| RPL19 | 4654.0 | 6782.0 |
| RTRAF | -2127.0 | 8772.0 |
| RUFY2 | 6866.0 | 4915.0 |
| RUFY3 | 5428.0 | -5971.0 |
| S100A10 | 7779.0 | 5985.0 |
| SCNM1 | 5490.0 | -5900.0 |
| SELP | 5864.0 | 2861.0 |
| SEMA6A | -6678.0 | 6683.0 |
| SEMA6C | 6649.0 | -2213.0 |
| SERF2 | -2395.0 | -2526.0 |
| SFSWAP | 5753.0 | -6334.0 |
| SLC12A5 | 1728.0 | -2402.0 |
| SLC14A2 | 5801.0 | -6223.0 |
| SLC18A1 | -1729.0 | -3428.0 |
| SLC25A14 | -1689.0 | -3486.0 |
| SLC35E2B | 1081.0 | 797.0 |
| SLC38A7 | -3658.0 | -5269.0 |
| SLC4A5 | 6363.0 | 612.0 |
| SLC66A1 | -1315.0 | -5738.0 |
| SMAD1 | 5880.0 | 5459.0 |
| SOX13 | 7723.0 | -5757.0 |
| SUGP2 | -4111.0 | -2000.0 |
| SUOX | 6862.0 | -1063.0 |
| TCF15 | -162.0 | 2805.0 |
| TCTN1 | 4752.0 | -6685.0 |
| TFG | -5471.0 | 5860.0 |
| TGFB3 | -1546.0 | 8322.0 |
| TIMM8A | 4496.0 | 7741.0 |
| TIMM8B | -1186.0 | 7371.0 |
| TIMM9 | -6212.0 | 1407.0 |
| TM6SF2 | 8051.0 | 1210.0 |
| TMEM104 | -119.0 | -4147.0 |
| TMEM223 | -3617.0 | 5440.0 |
| TMEM254 | -7257.0 | -5697.0 |
| TNPO2 | 2302.0 | -5963.0 |
| TNPO3 | -3142.0 | 2781.0 |
| TPCN1 | 5971.0 | -6632.0 |
| TRADD | -1318.0 | -2687.0 |
| TRIM2 | -1014.5 | 6967.5 |
| TRIM62 | 6914.0 | -31.0 |
| TTC1 | -896.0 | 7387.0 |
| TTF1 | -4501.0 | -2293.0 |
| TUG1 | -3603.0 | 5016.0 |
| TULP3 | -6456.0 | -4812.0 |
| USP13 | -642.0 | 3525.0 |
| VCL | -4796.0 | 7947.0 |
| YIPF6 | -4393.0 | 6442.0 |
| ZBTB40 | -7017.0 | -4622.0 |
| ZNF609 | 5163.0 | -835.0 |
| ZNF629 | 7746.0 | 563.0 |
GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_1MONTH_POST_DX_DN
| metric | value |
|---|---|
| setSize | 153 |
| pMANOVA | 0.217 |
| p.adjustMANOVA | 0.297 |
| s.dist | 0.0896 |
| s.diabetes | 0.0517 |
| s.mitoG | -0.0732 |
| p.diabetes | 0.271 |
| p.mitoG | 0.119 |
| Gene | diabetes | mitoG |
|---|---|---|
| ERF | 8190 | -6273 |
| ABCC10 | 6808 | -6598 |
| KLHL26 | 6872 | -6028 |
| PLCG1 | 8067 | -4962 |
| INPP5E | 6856 | -5834 |
| ANKZF1 | 5848 | -6670 |
| KCNMA1 | 7158 | -4954 |
| C3orf18 | 7780 | -4538 |
| ADGRA2 | 6742 | -4913 |
| RUFY3 | 5428 | -5971 |
| TCTN1 | 4752 | -6685 |
| PCBP4 | 5524 | -5626 |
| TAZ | 4420 | -6361 |
| CLASRP | 4106 | -6614 |
| NFIC | 5421 | -4653 |
| NOL6 | 7943 | -3108 |
| SKP2 | 5738 | -4232 |
| JAKMIP2 | 3767 | -6132 |
| EPOR | 7888 | -2666 |
| CDKN2C | 6608 | -3067 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| ABCC10 | 6808.0 | -6598.0 |
| ACTN2 | -160.0 | 4310.0 |
| ADGRA2 | 6742.0 | -4913.0 |
| ADSL | 2344.0 | -1198.0 |
| ALX1 | -683.0 | -381.0 |
| ANKZF1 | 5848.0 | -6670.0 |
| AQP6 | 5108.0 | -1644.0 |
| ATAT1 | -6757.0 | -6199.0 |
| ATXN3L | 633.5 | 4150.5 |
| B4GALT4 | 6095.0 | 4039.0 |
| B4GALT7 | 1147.0 | -2488.0 |
| BACE1 | 1099.0 | 3140.0 |
| BICD1 | -2065.0 | 6371.0 |
| BOLA1 | 2756.0 | -4124.0 |
| C11orf24 | 1434.0 | 3904.0 |
| C3orf18 | 7780.0 | -4538.0 |
| CASR | -5215.0 | -1382.0 |
| CBFA2T2 | 1753.0 | 5677.0 |
| CBY1 | -5032.0 | 4324.0 |
| CCDC51 | 3605.0 | -4365.0 |
| CCDC93 | -1710.0 | -439.0 |
| CCR1 | -3507.0 | 4981.0 |
| CCR7 | -4606.0 | -4191.0 |
| CD248 | 537.0 | 1642.0 |
| CD82 | 7938.0 | 1042.0 |
| CDKN2C | 6608.0 | -3067.0 |
| CENPI | -1339.0 | -6050.0 |
| CHTOP | -4615.0 | -1316.0 |
| CIITA | -5946.0 | -2698.0 |
| CLASRP | 4106.0 | -6614.0 |
| CNTNAP1 | 2965.0 | -4300.0 |
| COA4 | -3012.0 | 3241.0 |
| CPN2 | -1570.0 | -3447.0 |
| CSRNP2 | 6469.0 | 1246.0 |
| CXCL13 | -1107.0 | 4180.0 |
| CYP4F12 | 7297.5 | 2796.5 |
| CYREN | -3549.0 | -2232.0 |
| DARS2 | -5166.0 | 329.0 |
| DDX6 | -4502.0 | 5780.0 |
| DHX32 | -759.0 | 5873.0 |
| DIS3 | -6175.0 | 6931.0 |
| DNAJC28 | 3205.0 | 1021.0 |
| DNMBP | 4678.0 | 6019.0 |
| DST | 1303.0 | 1938.0 |
| EEF2KMT | 4275.0 | -1189.0 |
| EGR2 | -1617.0 | 4130.0 |
| EGR3 | -3140.0 | 2625.0 |
| EIF5B | -1780.0 | 8616.0 |
| EPOR | 7888.0 | -2666.0 |
| ERF | 8190.0 | -6273.0 |
| EXD2 | -471.0 | 839.0 |
| F2 | -3087.0 | 4699.0 |
| FABP1 | 289.0 | -1810.0 |
| FAM111A | -3910.0 | 3549.0 |
| FAM155B | -6604.0 | 550.0 |
| FAM171A1 | -6511.0 | -1380.0 |
| FGA | 4508.0 | 5893.0 |
| GFOD2 | 714.0 | -3471.0 |
| GIMAP5 | -4554.5 | 7057.5 |
| GMFG | 3969.0 | 7186.0 |
| GTF3C2 | 1131.0 | -6296.0 |
| GULP1 | 3722.0 | 7458.0 |
| HDAC7 | 5870.0 | -2839.0 |
| HIVEP2 | -4281.0 | 6509.0 |
| HMBS | 2651.0 | 6449.0 |
| HSPA1L | -3778.0 | -133.0 |
| HSPB7 | 5741.0 | -1096.0 |
| IL11 | -3409.0 | 1307.0 |
| IL16 | -238.0 | 5474.0 |
| ING4 | -4464.0 | -4099.0 |
| INPP5E | 6856.0 | -5834.0 |
| JAKMIP2 | 3767.0 | -6132.0 |
| KCNMA1 | 7158.0 | -4954.0 |
| KEL | 1962.0 | -4981.0 |
| KLF7 | -4593.0 | 8044.0 |
| KLHL22 | -810.5 | -5052.5 |
| KLHL26 | 6872.0 | -6028.0 |
| KPTN | 3882.0 | -3219.0 |
| LBHD1 | -5908.0 | 7848.0 |
| LIPE | 2527.0 | 415.0 |
| LRRC75B | -548.0 | -2539.0 |
| LRRC8E | 3102.0 | -2604.0 |
| MAP3K19 | 380.0 | 543.0 |
| MAP3K20 | 8060.0 | 6853.0 |
| MLYCD | -6254.0 | -1293.0 |
| MRPL17 | -3013.0 | 6746.0 |
| MTHFS | 179.5 | -3965.5 |
| MUS81 | 5269.0 | -2722.0 |
| NCKAP1L | -1592.0 | 4630.0 |
| NFIC | 5421.0 | -4653.0 |
| NOL6 | 7943.0 | -3108.0 |
| NOMO3 | -3756.0 | -1252.0 |
| NOP10 | 2308.0 | 5890.0 |
| PCBP4 | 5524.0 | -5626.0 |
| PCDH7 | 7022.0 | -805.0 |
| PCSK2 | -329.0 | -3823.0 |
| PDPK1 | -4074.0 | 1936.0 |
| PEX5L | 2843.0 | -306.0 |
| PIP5K1A | -1663.0 | 5148.0 |
| PLCG1 | 8067.0 | -4962.0 |
| PLEKHA1 | 4350.0 | -2221.0 |
| PRELID3A | 496.0 | -5362.0 |
| PRSS53 | -876.0 | 453.0 |
| PUS3 | -4535.0 | 6560.0 |
| RABEPK | 2166.0 | 960.0 |
| RABIF | -2521.0 | -1135.0 |
| RALGPS1 | 2494.0 | -5324.0 |
| RBMX2 | 4443.0 | 3927.0 |
| REXO2 | -5252.0 | 7861.0 |
| RGS5 | 5300.0 | 8040.0 |
| RNF113A | -3023.0 | 3421.0 |
| RNF167 | -1219.0 | -3078.0 |
| RNF25 | -27.0 | 1761.0 |
| ROBO3 | -5418.0 | -1877.0 |
| RPGR | 815.0 | -1281.0 |
| RPS16 | 6244.0 | 1119.0 |
| RTP4 | -2887.0 | 3910.0 |
| RUFY3 | 5428.0 | -5971.0 |
| RXRA | -5143.0 | 1552.0 |
| SEMA6C | 6649.0 | -2213.0 |
| SEPTIN9 | 4938.0 | -235.0 |
| SH2D3C | 6944.0 | 958.0 |
| SKP2 | 5738.0 | -4232.0 |
| SLC12A5 | 1728.0 | -2402.0 |
| SLC19A1 | 4798.0 | -4123.0 |
| SLC39A1 | 3529.0 | 1673.0 |
| SNX19 | 15.0 | 855.0 |
| SPSB1 | 7434.0 | 4252.0 |
| SRPK2 | 5994.0 | 1036.0 |
| SUOX | 6862.0 | -1063.0 |
| TAZ | 4420.0 | -6361.0 |
| TCTN1 | 4752.0 | -6685.0 |
| TEK | -2265.0 | 8575.0 |
| TFG | -5471.0 | 5860.0 |
| TGFB3 | -1546.0 | 8322.0 |
| TIMM8A | 4496.0 | 7741.0 |
| TIMM8B | -1186.0 | 7371.0 |
| TMEM104 | -119.0 | -4147.0 |
| TMEM223 | -3617.0 | 5440.0 |
| TRAF3 | -6416.0 | 5442.0 |
| TRIM2 | -1014.5 | 6967.5 |
| TRIM62 | 6914.0 | -31.0 |
| TSPAN32 | 1.0 | -162.0 |
| UBAP1 | -6158.0 | 7653.0 |
| VPS52 | -3308.0 | -5643.0 |
| WDR5B | -3983.0 | 2770.0 |
| WFDC1 | -2408.0 | 3727.0 |
| YIF1B | 5058.0 | -3729.0 |
| ZBTB40 | -7017.0 | -4622.0 |
| ZNF629 | 7746.0 | 563.0 |
| ZNF654 | -1490.0 | 8187.0 |
| ZNF692 | -813.0 | -6529.0 |
| ZNF778 | 743.5 | 3019.5 |
HP_INSULIN_RESISTANT_DIABETES_MELLITUS
| metric | value |
|---|---|
| setSize | 26 |
| pMANOVA | 0.761 |
| p.adjustMANOVA | 0.804 |
| s.dist | 0.0749 |
| s.diabetes | 0.041 |
| s.mitoG | 0.0627 |
| p.diabetes | 0.717 |
| p.mitoG | 0.58 |
| Gene | diabetes | mitoG |
|---|---|---|
| LEPR | 6227 | 8533 |
| STAT3 | 8126 | 4982 |
| PLAGL1 | 6416 | 5973 |
| KLF11 | 7284 | 1719 |
| APPL1 | 940 | 7089 |
| LIPE | 2527 | 415 |
| INSR | 3417 | 173 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| AGPAT2 | -4051 | -2429 |
| AKT2 | -4939 | 3281 |
| ALMS1 | 1616 | -638 |
| APPL1 | 940 | 7089 |
| BSCL2 | 4891 | -4593 |
| CIDEC | 6723 | -3643 |
| DCAF17 | -5679 | 335 |
| EIF2AK3 | -6386 | 3372 |
| GATA6 | -1651 | 6694 |
| HNF1A | 7450 | -6675 |
| HNF4A | -6855 | 4619 |
| INSR | 3417 | 173 |
| KCNJ11 | 2961 | -3265 |
| KLF11 | 7284 | 1719 |
| LEPR | 6227 | 8533 |
| LIPE | 2527 | 415 |
| LMNA | 5092 | -3667 |
| NSMCE2 | 5776 | -3866 |
| PIK3R1 | -839 | 8363 |
| PLAGL1 | 6416 | 5973 |
| PLIN1 | -3309 | -4723 |
| PPARG | -3636 | 5654 |
| STAT3 | 8126 | 4982 |
| XRCC4 | -4715 | 7026 |
| ZFP57 | -749 | -781 |
| ZMPSTE24 | -6405 | 5555 |
KEGG_TYPE_II_DIABETES_MELLITUS
| metric | value |
|---|---|
| setSize | 41 |
| pMANOVA | 0.721 |
| p.adjustMANOVA | 0.785 |
| s.dist | 0.0692 |
| s.diabetes | 0.0108 |
| s.mitoG | 0.0684 |
| p.diabetes | 0.905 |
| p.mitoG | 0.449 |
| Gene | diabetes | mitoG |
|---|---|---|
| PKM | 7561.0 | 7758.0 |
| HK1 | 7506.0 | 4598.0 |
| PIK3R3 | 3779.5 | 8820.5 |
| SOCS3 | 4231.0 | 7185.0 |
| MAPK3 | 5390.0 | 5167.0 |
| MAPK9 | 2849.0 | 6624.0 |
| SLC2A2 | 7902.0 | 2301.0 |
| SOCS2 | 4529.0 | 3280.0 |
| PRKCD | 365.0 | 1901.0 |
| INSR | 3417.0 | 173.0 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| ADIPOQ | 3018.0 | -3550.0 |
| CACNA1A | 1894.0 | -3861.0 |
| CACNA1C | -234.0 | -2843.0 |
| CACNA1D | 1453.0 | -2159.0 |
| CACNA1E | -3623.0 | 599.0 |
| CACNA1G | 4776.0 | -33.0 |
| HK1 | 7506.0 | 4598.0 |
| HK2 | -1356.0 | 5521.0 |
| HK3 | -4874.0 | 2139.0 |
| IKBKB | -1785.0 | -5829.0 |
| INSR | 3417.0 | 173.0 |
| IRS1 | 7064.0 | -5549.0 |
| IRS2 | -582.0 | 3045.0 |
| KCNJ11 | 2961.0 | -3265.0 |
| MAFA | -3053.0 | 2846.0 |
| MAPK1 | -3928.0 | 6920.0 |
| MAPK10 | -2089.0 | -137.0 |
| MAPK3 | 5390.0 | 5167.0 |
| MAPK8 | -3252.0 | 1695.0 |
| MAPK9 | 2849.0 | 6624.0 |
| MTOR | -4145.0 | -2344.0 |
| PIK3CA | -6347.0 | 2923.0 |
| PIK3CB | -1756.0 | 1880.0 |
| PIK3CD | -1968.0 | 1889.0 |
| PIK3CG | -5373.0 | 8065.0 |
| PIK3R1 | -839.0 | 8363.0 |
| PIK3R2 | 1669.5 | -3969.5 |
| PIK3R3 | 3779.5 | 8820.5 |
| PIK3R5 | -1994.0 | 2879.0 |
| PKLR | 8195.0 | -127.0 |
| PKM | 7561.0 | 7758.0 |
| PRKCD | 365.0 | 1901.0 |
| PRKCE | -5671.0 | 2371.0 |
| PRKCZ | -2030.0 | -5814.0 |
| SLC2A2 | 7902.0 | 2301.0 |
| SLC2A4 | 8055.0 | -2624.0 |
| SOCS1 | -253.0 | -5520.0 |
| SOCS2 | 4529.0 | 3280.0 |
| SOCS3 | 4231.0 | 7185.0 |
| SOCS4 | -6470.0 | 7880.0 |
| TNF | -2778.0 | 4883.0 |
TNFR1-induced NFkappaB signaling pathway
| metric | value |
|---|---|
| setSize | 26 |
| pMANOVA | 0.83 |
| p.adjustMANOVA | 0.83 |
| s.dist | 0.0633 |
| s.diabetes | 0.0226 |
| s.mitoG | 0.0591 |
| p.diabetes | 0.842 |
| p.mitoG | 0.602 |
| Gene | diabetes | mitoG |
|---|---|---|
| TNFRSF1A | 6733 | 6743 |
| BIRC3 | 6091 | 6158 |
| TAB3 | 3966 | 5424 |
| MAP3K7 | 1594 | 7480 |
| USP2 | 7977 | 982 |
| OTUD7B | 3158 | 927 |
| SHARPIN | 4794 | 164 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| BIRC2 | -4230.0 | 3665.0 |
| BIRC3 | 6091.0 | 6158.0 |
| CHUK | -3701.0 | 8556.0 |
| CYLD | -4935.0 | 4060.0 |
| IKBKB | -1785.0 | -5829.0 |
| IKBKG | 3700.0 | -677.0 |
| MAP3K7 | 1594.0 | 7480.0 |
| OTUD7B | 3158.0 | 927.0 |
| RACK1 | 3367.0 | -321.0 |
| RBCK1 | 3790.0 | -3921.0 |
| RIPK1 | -2977.0 | 5088.0 |
| RNF31 | 6112.5 | -6521.5 |
| SHARPIN | 4794.0 | 164.0 |
| TAB1 | 7839.0 | -5339.0 |
| TAB2 | -7040.0 | 7307.0 |
| TAB3 | 3966.0 | 5424.0 |
| TNF | -2778.0 | 4883.0 |
| TNFAIP3 | -151.0 | 2986.0 |
| TNFRSF1A | 6733.0 | 6743.0 |
| TRADD | -1318.0 | -2687.0 |
| TRAF1 | -3550.0 | -834.0 |
| TRAF2 | 3405.0 | -3806.0 |
| USP2 | 7977.0 | 982.0 |
| USP21 | -4905.0 | -5030.0 |
| USP4 | -3801.0 | 1470.0 |
| XIAP | -4862.0 | 7852.0 |
HP_DIABETES_INSIPIDUS
| metric | value |
|---|---|
| setSize | 33 |
| pMANOVA | 0.82 |
| p.adjustMANOVA | 0.83 |
| s.dist | 0.0576 |
| s.diabetes | 0.0529 |
| s.mitoG | 0.0229 |
| p.diabetes | 0.599 |
| p.mitoG | 0.82 |
| Gene | diabetes | mitoG |
|---|---|---|
| AQP2 | 8177 | 5602 |
| AKT1 | 4859 | 7244 |
| ROBO1 | 3335 | 7441 |
| GPR161 | 6595 | 3757 |
| AVPR2 | 4980 | 2853 |
| GLA | 1196 | 3449 |
| ARNT2 | 8205 | 310 |
| OCRL | 3974 | 593 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| AKT1 | 4859.0 | 7244.0 |
| ALMS1 | 1616.0 | -638.0 |
| AQP2 | 8177.0 | 5602.0 |
| ARL6 | -1042.0 | 6323.0 |
| ARNT2 | 8205.0 | 310.0 |
| AVPR2 | 4980.0 | 2853.0 |
| BBS1 | 3353.5 | -2595.5 |
| BRAF | -6284.0 | 4955.0 |
| CCDC28B | 7087.0 | -523.0 |
| CDON | -5264.0 | 357.0 |
| CISD2 | -5462.0 | 6479.0 |
| CNOT1 | -2585.0 | 3418.0 |
| CTNNB1 | -6022.0 | 2664.0 |
| FGFR1 | 6753.0 | -812.0 |
| GLA | 1196.0 | 3449.0 |
| GLI2 | -1482.0 | 794.0 |
| GPR161 | 6595.0 | 3757.0 |
| HESX1 | 5292.0 | -1586.0 |
| HLA-DRB1 | 1762.5 | -4711.5 |
| LHX4 | -3273.0 | 943.0 |
| OCRL | 3974.0 | 593.0 |
| PROKR2 | -2068.0 | -3287.0 |
| PRPS1 | -6688.0 | 3956.0 |
| PTEN | -5726.0 | 8365.0 |
| PTPN22 | -5957.0 | 3364.0 |
| ROBO1 | 3335.0 | 7441.0 |
| SHH | -4143.0 | -5003.0 |
| STRADA | 5090.0 | -5448.0 |
| TP63 | -3604.0 | 1254.0 |
| VIPAS39 | -1721.0 | 3736.0 |
| VPS33B | 2918.5 | -5911.5 |
| WDR11 | 7162.0 | -4436.0 |
| WFS1 | 7688.0 | -3009.0 |
GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_4MONTH_POST_DX_DN
| metric | value |
|---|---|
| setSize | 160 |
| pMANOVA | 0.425 |
| p.adjustMANOVA | 0.537 |
| s.dist | 0.0535 |
| s.diabetes | -0.0311 |
| s.mitoG | -0.0435 |
| p.diabetes | 0.497 |
| p.mitoG | 0.343 |
| Gene | diabetes | mitoG |
|---|---|---|
| DDX17 | -6389.0 | -6574.0 |
| ZMYM6 | -6630.0 | -5108.0 |
| TWNK | -6338.0 | -5118.0 |
| SDF2 | -5624.0 | -4467.0 |
| ZKSCAN4 | -3447.0 | -5890.0 |
| VPS52 | -3308.0 | -5643.0 |
| ING4 | -4464.0 | -4099.0 |
| ZSCAN26 | -3909.0 | -4571.0 |
| CACNG4 | -3655.0 | -4722.0 |
| PPT2 | -5191.5 | -2667.5 |
| KCNG1 | -4013.0 | -2822.0 |
| MLYCD | -6254.0 | -1293.0 |
| CYREN | -3549.0 | -2232.0 |
| PAX8 | -1678.0 | -3864.0 |
| CHTOP | -4615.0 | -1316.0 |
| NOMO3 | -3756.0 | -1252.0 |
| FERMT1 | -2538.0 | -1690.0 |
| KLHL22 | -810.5 | -5052.5 |
| RNF167 | -1219.0 | -3078.0 |
| UTP25 | -910.0 | -3889.0 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| ABHD6 | 6359.0 | 7038.0 |
| ACSM5 | 7609.0 | -5870.0 |
| ACTN2 | -160.0 | 4310.0 |
| ADGRA2 | 6742.0 | -4913.0 |
| ALKBH1 | 2546.0 | -3262.0 |
| AOC3 | -497.0 | 5099.0 |
| AQP6 | 5108.0 | -1644.0 |
| ARHGAP25 | 1343.0 | 6238.0 |
| ARHGAP35 | -2056.0 | 7180.0 |
| ARHGEF5 | -5926.0 | 5828.0 |
| ATXN3L | 633.5 | 4150.5 |
| BICD1 | -2065.0 | 6371.0 |
| BOLA1 | 2756.0 | -4124.0 |
| CACNG4 | -3655.0 | -4722.0 |
| CBFA2T2 | 1753.0 | 5677.0 |
| CBY1 | -5032.0 | 4324.0 |
| CCDC51 | 3605.0 | -4365.0 |
| CD248 | 537.0 | 1642.0 |
| CD52 | -3982.0 | 3448.0 |
| CDC123 | 1994.0 | 3040.0 |
| CDH11 | -3726.0 | 7616.0 |
| CDKN2C | 6608.0 | -3067.0 |
| CELSR3 | 532.0 | -1725.0 |
| CHPF | 638.0 | -574.0 |
| CHTOP | -4615.0 | -1316.0 |
| CKAP5 | -2537.0 | 8372.0 |
| COMMD3 | -4289.0 | 8822.0 |
| COQ6 | 1950.0 | -3453.0 |
| CRIPT | -1489.0 | 8618.0 |
| CSRNP2 | 6469.0 | 1246.0 |
| CTF1 | 601.0 | -5358.0 |
| CYP4F12 | 7297.5 | 2796.5 |
| CYREN | -3549.0 | -2232.0 |
| CZIB | -327.0 | 2043.0 |
| DARS2 | -5166.0 | 329.0 |
| DDX17 | -6389.0 | -6574.0 |
| DDX6 | -4502.0 | 5780.0 |
| DENND2D | 3945.0 | -4019.0 |
| DHX32 | -759.0 | 5873.0 |
| DMWD | 1282.0 | -6400.0 |
| DNAJA3 | -1658.0 | 5339.0 |
| DNAL4 | 1096.0 | -1389.0 |
| DST | 1303.0 | 1938.0 |
| DYNLRB1 | 5057.0 | -2847.0 |
| DZANK1 | 5408.0 | -4689.0 |
| EFNA3 | 5736.0 | 1687.0 |
| EGR2 | -1617.0 | 4130.0 |
| EPOR | 7888.0 | -2666.0 |
| ERF | 8190.0 | -6273.0 |
| EXD2 | -471.0 | 839.0 |
| FAM155B | -6604.0 | 550.0 |
| FAM234B | 5197.0 | -129.0 |
| FERMT1 | -2538.0 | -1690.0 |
| FOXO4 | 257.0 | -4431.0 |
| GEMIN6 | 779.0 | 3452.0 |
| GLS | 5704.0 | 3155.0 |
| GPR171 | -4112.0 | 6669.0 |
| GPR182 | 7524.0 | 5618.0 |
| GPR52 | 841.0 | -5121.0 |
| HDAC11 | 6709.0 | -5647.0 |
| HECTD4 | -439.0 | -5909.0 |
| HINFP | 297.0 | 1595.0 |
| HOXA2 | 1984.0 | -3355.0 |
| ID3 | 4145.0 | -2671.0 |
| IL11 | -3409.0 | 1307.0 |
| IL23A | -2852.0 | 2958.0 |
| ING4 | -4464.0 | -4099.0 |
| INO80B | 6545.5 | -3302.5 |
| ITFG2 | 826.0 | -4600.0 |
| JAKMIP2 | 3767.0 | -6132.0 |
| KCNG1 | -4013.0 | -2822.0 |
| KIFBP | -2867.0 | 1916.0 |
| KLHL22 | -810.5 | -5052.5 |
| LARGE1 | 1668.0 | 1564.0 |
| LIPE | 2527.0 | 415.0 |
| LLGL1 | 6871.0 | -3990.0 |
| LRRC20 | 7602.0 | -584.0 |
| LRRC75B | -548.0 | -2539.0 |
| MAP3K20 | 8060.0 | 6853.0 |
| MED20 | 2722.0 | -6368.0 |
| MFAP1 | -1345.0 | 8624.0 |
| MFAP3 | 2866.0 | 4624.0 |
| MLYCD | -6254.0 | -1293.0 |
| MMACHC | 1165.0 | 5604.0 |
| MRPL17 | -3013.0 | 6746.0 |
| MRPL35 | -1990.0 | 4213.0 |
| MTERF3 | -5919.0 | 3270.0 |
| MTHFS | 179.5 | -3965.5 |
| MUS81 | 5269.0 | -2722.0 |
| N4BP1 | -5080.0 | 168.0 |
| NCKAP1L | -1592.0 | 4630.0 |
| NDUFA3 | 4319.0 | 82.0 |
| NIF3L1 | -4467.0 | -285.0 |
| NOMO3 | -3756.0 | -1252.0 |
| NOP10 | 2308.0 | 5890.0 |
| ORMDL2 | -5602.0 | -556.0 |
| PAX8 | -1678.0 | -3864.0 |
| PEX12 | 3372.0 | 1451.0 |
| PGM3 | -5155.0 | -58.0 |
| PIP5K1A | -1663.0 | 5148.0 |
| PLEKHA1 | 4350.0 | -2221.0 |
| PLEKHA4 | 3114.0 | -4509.0 |
| PNP | -7335.0 | 8459.0 |
| POGLUT1 | -1880.0 | 2758.0 |
| POLR3K | -5432.0 | 6617.0 |
| PPME1 | 4194.0 | 3066.0 |
| PPP2R5B | 627.0 | 5414.0 |
| PPT2 | -5191.5 | -2667.5 |
| PRELID3A | 496.0 | -5362.0 |
| PTPN21 | 2719.0 | -4215.0 |
| PTRH2 | -3116.0 | 273.0 |
| PUS3 | -4535.0 | 6560.0 |
| RABEPK | 2166.0 | 960.0 |
| RABIF | -2521.0 | -1135.0 |
| RALGPS1 | 2494.0 | -5324.0 |
| RNF167 | -1219.0 | -3078.0 |
| RNF34 | 48.0 | 4672.0 |
| RPA3 | 3029.0 | 1440.0 |
| RPGR | 815.0 | -1281.0 |
| RPP38 | -3284.0 | 7004.0 |
| RPS16 | 6244.0 | 1119.0 |
| RRAGA | -3310.0 | 5815.0 |
| RTP4 | -2887.0 | 3910.0 |
| SDF2 | -5624.0 | -4467.0 |
| SDHAF1 | 3386.0 | 2256.0 |
| SEMA6C | 6649.0 | -2213.0 |
| SLC39A1 | 3529.0 | 1673.0 |
| SNX1 | -5578.0 | 5338.0 |
| SNX19 | 15.0 | 855.0 |
| SPSB1 | 7434.0 | 4252.0 |
| SRPK2 | 5994.0 | 1036.0 |
| SSBP2 | 440.0 | 2334.0 |
| STAM2 | 494.0 | 2564.0 |
| SYNRG | -6000.0 | 2901.0 |
| TAF5L | 3299.0 | 3056.0 |
| TAPT1 | 5653.0 | 5450.0 |
| TEK | -2265.0 | 8575.0 |
| TGFB3 | -1546.0 | 8322.0 |
| TIMM8B | -1186.0 | 7371.0 |
| TM6SF2 | 8051.0 | 1210.0 |
| TMEM177 | -4126.0 | 2220.0 |
| TMEM223 | -3617.0 | 5440.0 |
| TRIM27 | -452.0 | -3380.0 |
| TWNK | -6338.0 | -5118.0 |
| UBA52 | 7488.0 | -4269.0 |
| UMPS | 4556.0 | -2755.0 |
| UTP25 | -910.0 | -3889.0 |
| VPS52 | -3308.0 | -5643.0 |
| WDR3 | -6076.0 | 2575.0 |
| WDR5B | -3983.0 | 2770.0 |
| WFDC1 | -2408.0 | 3727.0 |
| YIF1B | 5058.0 | -3729.0 |
| ZBTB3 | -4740.0 | 1707.0 |
| ZKSCAN4 | -3447.0 | -5890.0 |
| ZMYM6 | -6630.0 | -5108.0 |
| ZNF174 | 3917.0 | -6183.0 |
| ZNF189 | -6118.0 | 3732.0 |
| ZNF646 | 3812.0 | 2258.0 |
| ZNF764 | -229.0 | 5915.0 |
| ZSCAN26 | -3909.0 | -4571.0 |
GSE9006_HEALTHY_VS_TYPE_2_DIABETES_PBMC_AT_DX_UP
| metric | value |
|---|---|
| setSize | 189 |
| pMANOVA | 0.648 |
| p.adjustMANOVA | 0.749 |
| s.dist | 0.0431 |
| s.diabetes | 0.0254 |
| s.mitoG | -0.0348 |
| p.diabetes | 0.548 |
| p.mitoG | 0.41 |
| Gene | diabetes | mitoG |
|---|---|---|
| CCDC85B | 7941 | -6322 |
| DEAF1 | 7709 | -5938 |
| ZNF512B | 7028 | -6394 |
| NADSYN1 | 6875 | -6478 |
| COTL1 | 8183 | -5409 |
| NSMF | 6719 | -6004 |
| SNRPF | 6058 | -6379 |
| ATP5F1E | 6241 | -5774 |
| ATP5MC3 | 6278 | -5724 |
| MVP | 6785 | -5147 |
| MFSD10 | 6323 | -5202 |
| RNF126 | 5755 | -4740 |
| POLR2E | 7128 | -3504 |
| TSR3 | 4228 | -5856 |
| AP5Z1 | 3582 | -6569 |
| SAFB2 | 3321 | -6673 |
| DAZAP1 | 5026 | -4228 |
| SAC3D1 | 4799 | -4190 |
| FBXL15 | 4607 | -4358 |
| VPS51 | 3048 | -6458 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| ADNP2 | 2146.0 | 595.0 |
| ADRM1 | -6170.0 | -477.0 |
| AHCY | -3362.0 | -6342.0 |
| ANXA6 | 2396.0 | 7859.0 |
| AP5Z1 | 3582.0 | -6569.0 |
| APRT | 7257.0 | -2499.0 |
| ARHGEF1 | 3750.0 | -3695.0 |
| ARPC4 | 3077.0 | 1525.0 |
| ATP1B3 | -1025.0 | 8436.0 |
| ATP5F1D | 5225.0 | 673.0 |
| ATP5F1E | 6241.0 | -5774.0 |
| ATP5MC3 | 6278.0 | -5724.0 |
| ATP5ME | 3268.0 | 3202.0 |
| AURKAIP1 | 4765.0 | 3868.0 |
| BCL7C | -6117.0 | 4975.0 |
| BICRAL | 1780.0 | -4299.0 |
| BTF3 | -2304.0 | 8350.0 |
| C9orf16 | 4926.0 | 854.0 |
| CALM3 | -2691.0 | 4626.0 |
| CAPN15 | -874.0 | -5739.0 |
| CBX4 | 3352.0 | -2144.0 |
| CCDC22 | -4166.0 | -3221.0 |
| CCDC85B | 7941.0 | -6322.0 |
| CD3E | -1202.0 | 619.0 |
| CD81 | 3188.0 | 6614.0 |
| CDC37 | -682.0 | -4414.0 |
| CDCA4 | 4122.0 | 2492.0 |
| CFDP1 | -4681.0 | 7182.0 |
| CFL1 | -1720.0 | 8321.0 |
| CHCHD3 | -2623.0 | 7919.0 |
| CNOT3 | 1322.0 | -5732.0 |
| COPG1 | -3891.0 | 3599.0 |
| COPS7B | -2394.0 | -5916.0 |
| CORO1B | 40.0 | -5224.0 |
| COTL1 | 8183.0 | -5409.0 |
| DAZAP1 | 5026.0 | -4228.0 |
| DBI | -3860.0 | 5119.0 |
| DDX49 | 4404.0 | -1145.0 |
| DEAF1 | 7709.0 | -5938.0 |
| DGKZ | -6561.0 | -2123.0 |
| DNAJC7 | -426.0 | 397.0 |
| DOK2 | 3914.0 | 1693.0 |
| DRAP1 | 5968.0 | 6776.0 |
| ECSIT | -3596.0 | 1408.0 |
| EDEM2 | -3522.0 | -3508.0 |
| EDF1 | 2958.0 | -483.0 |
| EIF3F | 2793.0 | 1790.0 |
| EIF4H | 5370.0 | -98.0 |
| ELF4 | -1062.0 | 5556.0 |
| ELOC | -3325.0 | 7837.0 |
| ERH | -4330.0 | 2173.0 |
| ERP29 | -6677.0 | -3655.0 |
| FAM53B | 6631.0 | 2759.0 |
| FBXL15 | 4607.0 | -4358.0 |
| FCHO1 | 3015.0 | 1348.0 |
| FOXK2 | -5706.0 | 1999.0 |
| GATAD2A | -190.0 | 5669.0 |
| GID8 | -1864.0 | 6771.0 |
| GLUD1 | 8064.5 | 3730.5 |
| GPS2 | 1228.0 | 2826.0 |
| GSN | 7535.0 | 7997.0 |
| GTF2F1 | 373.0 | 6337.0 |
| GZMM | 1140.0 | -3497.0 |
| HMG20B | 6566.0 | -1264.0 |
| HMOX1 | -7076.0 | 8232.0 |
| HNRNPK | -808.0 | 7246.0 |
| HNRNPM | -6548.0 | -2929.0 |
| HNRNPR | -3972.0 | 1045.0 |
| HNRNPU | -5219.0 | 7082.0 |
| HNRNPUL1 | 4431.0 | 1071.0 |
| HRAS | 1503.0 | -318.0 |
| HSF1 | -1770.0 | -3977.0 |
| HSPA9 | -566.0 | 8181.0 |
| ID2 | -4980.0 | 862.0 |
| IDS | -4361.5 | 6034.5 |
| IDUA | 4110.0 | 3194.0 |
| ILKAP | -3346.0 | -3704.0 |
| ILVBL | 3004.0 | -6442.0 |
| LIMD2 | 2317.0 | 1635.0 |
| LIMK1 | 3519.0 | 2264.0 |
| LPCAT4 | 3374.0 | 1637.0 |
| LRRC47 | 3220.0 | 934.0 |
| LSM12 | -2869.0 | 4929.0 |
| LTBP4 | -6699.0 | 5054.0 |
| MAP2K2 | -2882.5 | -4769.5 |
| MARCKSL1 | -107.0 | 7707.0 |
| MCUR1 | -1414.0 | 1795.0 |
| MDH2 | 3713.0 | 4456.0 |
| MEAF6 | 2763.0 | -1411.0 |
| MFNG | -2815.0 | 5728.0 |
| MFSD10 | 6323.0 | -5202.0 |
| MINK1 | -4877.0 | -2450.0 |
| MRPL12 | -2913.0 | 4144.0 |
| MRPS15 | 2010.0 | 4604.0 |
| MSN | -1294.0 | 5246.0 |
| MTA1 | -1428.0 | -2770.0 |
| MVP | 6785.0 | -5147.0 |
| MYG1 | -658.0 | -3758.0 |
| MYH9 | 7189.0 | 7115.0 |
| NAA60 | -1707.0 | 521.0 |
| NADSYN1 | 6875.0 | -6478.0 |
| NDRG2 | -6784.0 | 2803.0 |
| NDUFB8 | 4901.5 | 6790.5 |
| NDUFC1 | 1620.0 | 3968.0 |
| NDUFS8 | 1961.0 | 2910.0 |
| NONO | -5056.0 | 5895.0 |
| NSMF | 6719.0 | -6004.0 |
| NUTF2 | -2549.0 | 1665.0 |
| OSTF1 | 6553.0 | 5854.0 |
| PAK2 | -4906.0 | 6708.0 |
| PBX2 | 3702.0 | -1442.0 |
| PCBP1 | -6097.0 | -710.0 |
| PDAP1 | 3245.0 | 700.0 |
| PDIA3 | -7283.0 | 7821.0 |
| PDIA4 | -7329.0 | 7729.0 |
| PDLIM2 | 6653.0 | 4632.0 |
| PFDN2 | -1073.0 | 7198.0 |
| PFN1 | -3462.0 | -4129.0 |
| PKN1 | 4322.0 | -4516.0 |
| POLR2E | 7128.0 | -3504.0 |
| PPP1R14B | 1139.0 | -4448.0 |
| PRCC | -3064.0 | -3244.0 |
| PRPF31 | -387.0 | 4117.0 |
| PSMB10 | 3752.0 | -908.0 |
| PTBP1 | -4264.0 | -2729.0 |
| PTPRCAP | -2234.0 | -289.0 |
| R3HCC1 | 7667.0 | -1069.0 |
| RAB5C | 3703.0 | 3375.0 |
| RALY | -4431.0 | 5639.0 |
| RASGRP2 | -326.0 | -409.0 |
| RBCK1 | 3790.0 | -3921.0 |
| RBM3 | 8175.0 | 5192.0 |
| RDH14 | 2827.0 | -2645.0 |
| REX1BD | 1924.0 | -3848.0 |
| RNF126 | 5755.0 | -4740.0 |
| RNF19B | -3119.0 | -1959.0 |
| RNPS1 | 5559.0 | 6960.0 |
| RPL37 | 2109.0 | -667.0 |
| RPLP2 | 3550.0 | 3555.0 |
| RPN1 | -7121.0 | 7464.0 |
| SAC3D1 | 4799.0 | -4190.0 |
| SAFB | -1933.0 | -1132.0 |
| SAFB2 | 3321.0 | -6673.0 |
| SART1 | 2632.0 | -1920.0 |
| SEC61G | -2855.0 | 8720.0 |
| SERPINF1 | 645.0 | 2834.0 |
| SF3A2 | 1864.0 | -5244.0 |
| SF3B4 | 2644.0 | -4321.0 |
| SFPQ | -5196.0 | -4828.0 |
| SH3GLB2 | 284.0 | -2915.0 |
| SLC25A1 | 3746.0 | 544.0 |
| SLC52A2 | -6134.0 | -6313.0 |
| SMARCD2 | -3787.0 | 113.0 |
| SMIM10L1 | -5327.0 | 7775.0 |
| SNF8 | 2397.0 | -3270.0 |
| SNRPF | 6058.0 | -6379.0 |
| SPCS3 | 4330.0 | 1501.0 |
| SRP14 | 372.0 | 5948.0 |
| SRRM1 | 5551.0 | 7062.0 |
| SRSF9 | -2009.0 | -5029.0 |
| SSBP3 | 5860.0 | -2107.0 |
| SSH1 | 1827.0 | -4164.0 |
| SSRP1 | 2663.0 | 4754.0 |
| ST6GALNAC4 | -365.0 | 4860.0 |
| STARD3 | -3871.0 | -6390.0 |
| STK25 | 6890.0 | 2565.0 |
| SUMO3 | -7259.0 | 7825.0 |
| TAF10 | -3030.0 | 2638.0 |
| TGFB1 | -1851.0 | 6152.0 |
| THOC6 | -3723.0 | -3958.0 |
| TKT | 8181.0 | 2150.0 |
| TLE5 | 376.0 | 3434.0 |
| TMED9 | -5309.0 | -1036.0 |
| TNFRSF14 | 872.0 | -1648.0 |
| TP53 | 2557.0 | -3561.0 |
| TRAPPC2 | -3263.0 | 6403.0 |
| TSPAN14 | -6627.0 | 1158.0 |
| TSR3 | 4228.0 | -5856.0 |
| U2AF2 | -2150.0 | -825.0 |
| UBE2S | 4549.0 | -1742.0 |
| UCP2 | 6987.0 | 4595.0 |
| UQCRB | -410.0 | 8334.0 |
| VPS4A | -5731.5 | 7213.5 |
| VPS51 | 3048.0 | -6458.0 |
| WDR18 | -5000.0 | -3150.0 |
| WDR45 | 1445.0 | -2878.0 |
| XAB2 | 2873.0 | 3916.0 |
| ZNF512B | 7028.0 | -6394.0 |
| ZNF580 | 6166.0 | 515.0 |
GSE9006_1MONTH_VS_4MONTH_POST_TYPE_1_DIABETES_DX_PBMC_DN
| metric | value |
|---|---|
| setSize | 152 |
| pMANOVA | 0.721 |
| p.adjustMANOVA | 0.785 |
| s.dist | 0.035 |
| s.diabetes | 0.033 |
| s.mitoG | 0.0114 |
| p.diabetes | 0.483 |
| p.mitoG | 0.808 |
| Gene | diabetes | mitoG |
|---|---|---|
| COX7B | 6102 | 8760 |
| ABCC2 | 8240 | 5236 |
| GSTO1 | 8023 | 4922 |
| FERMT2 | 5215 | 7566 |
| MCTP2 | 5673 | 6385 |
| RAB30 | 6435 | 5622 |
| TMPRSS2 | 7909 | 4409 |
| S1PR1 | 4311 | 7637 |
| MBTPS2 | 5009 | 5876 |
| DENND2B | 7796 | 3470 |
| TRPC3 | 4682 | 5766 |
| SIAH1 | 4474 | 5949 |
| RECK | 5456 | 4804 |
| IL1R1 | 3443 | 7288 |
| PSMF1 | 5087 | 4771 |
| LFNG | 7713 | 3016 |
| BHLHE41 | 8219 | 2676 |
| UPB1 | 7323 | 2972 |
| SLC66A3 | 3663 | 5856 |
| KCNJ10 | 3384 | 6290 |
Click HERE to show all gene set members
| diabetes | mitoG | |
|---|---|---|
| ABCC2 | 8240.0 | 5236.0 |
| ADAMTSL2 | 1075.0 | 7367.0 |
| AK2 | 3153.0 | 197.0 |
| APOO | -605.0 | 8803.0 |
| ARFRP1 | 702.0 | -6512.0 |
| ARNT | 1247.0 | 2255.0 |
| ASB4 | 2909.0 | 2350.0 |
| ATP6V0E1 | 1832.0 | 3873.0 |
| B3GNT2 | 830.0 | -6274.0 |
| BAIAP2 | 7911.0 | 534.0 |
| BGLAP | -4940.0 | -647.0 |
| BHLHE41 | 8219.0 | 2676.0 |
| C4BPA | -1940.0 | -3551.0 |
| CA4 | -6448.0 | 2608.0 |
| CACNA1D | 1453.0 | -2159.0 |
| CD72 | -4839.0 | 3828.0 |
| CDK20 | -6202.0 | -712.0 |
| CELSR3 | 532.0 | -1725.0 |
| CFAP43 | -4048.0 | 2739.0 |
| CKLF | -2218.0 | -2093.0 |
| CLCN4 | -6858.0 | 6649.0 |
| CLDN3 | 6311.0 | -1143.0 |
| CNIH1 | -3991.0 | 8144.0 |
| COL5A3 | 990.0 | -5143.0 |
| COX6A1 | 5658.0 | -2138.0 |
| COX7B | 6102.0 | 8760.0 |
| CPLX2 | 4986.0 | -881.0 |
| DCLK1 | 1860.0 | 2862.0 |
| DCTN1 | 7218.0 | -3098.0 |
| DENND2B | 7796.0 | 3470.0 |
| DNAJB4 | -4770.0 | 7917.0 |
| DR1 | 1246.0 | 8550.0 |
| DRC3 | 4772.0 | -4087.0 |
| EDN1 | -1177.0 | 7690.0 |
| EIF4E | -4500.0 | 8429.0 |
| ENTPD7 | -6301.0 | -4494.0 |
| EPHA1 | 6217.0 | -5787.0 |
| EPHA3 | 882.0 | 7728.0 |
| ERI3 | 5821.0 | -4367.0 |
| ETNK1 | 7979.0 | 553.0 |
| EXD2 | -471.0 | 839.0 |
| F10 | 7628.0 | -1082.0 |
| FAM114A2 | -4892.0 | 3284.0 |
| FAP | -316.0 | 2909.0 |
| FCMR | 908.0 | 2646.0 |
| FERMT2 | 5215.0 | 7566.0 |
| FGF22 | 7063.0 | -4758.0 |
| FZR1 | 3996.0 | -5000.0 |
| GABRA2 | -3873.0 | 2553.0 |
| GART | -5631.0 | -3257.0 |
| GOLIM4 | -2600.0 | 7173.0 |
| GOLPH3L | -5413.0 | 8354.0 |
| GPRIN2 | 7637.0 | -2891.0 |
| GSTO1 | 8023.0 | 4922.0 |
| GUCY1A2 | 1000.0 | 5104.0 |
| GUCY2D | 2541.0 | -2990.0 |
| GUCY2F | 2125.0 | -5729.0 |
| HAPLN1 | -6240.0 | 1410.0 |
| HS3ST3B1 | 2983.0 | 5715.0 |
| HSP90B1 | -7279.0 | 8368.0 |
| HYAL2 | -2781.0 | -4258.0 |
| IGKC | -2925.0 | 7318.0 |
| IGKV1D-13 | 2052.5 | 4944.5 |
| IL1R1 | 3443.0 | 7288.0 |
| INHA | 5991.0 | -2589.0 |
| ITGB1BP2 | 1164.0 | -5767.0 |
| JMJD4 | 458.0 | -4829.0 |
| KCNJ10 | 3384.0 | 6290.0 |
| KCNJ5 | 2267.0 | 2954.0 |
| KDM4A | 6153.5 | -3924.5 |
| KLHDC8A | -3539.0 | 2328.0 |
| KLRC4 | -2897.5 | 4049.5 |
| KRT23 | -660.0 | 3043.0 |
| LEPROTL1 | -4998.0 | 2148.0 |
| LFNG | 7713.0 | 3016.0 |
| LSM1 | 1559.0 | 3093.0 |
| LY6G6D | 4861.0 | -2442.0 |
| MBD5 | -1298.0 | -5280.0 |
| MBNL3 | 3179.0 | -2024.0 |
| MBTPS2 | 5009.0 | 5876.0 |
| MCTP2 | 5673.0 | 6385.0 |
| MDM4 | -2223.0 | -5305.0 |
| MEF2A | -2071.0 | 7495.0 |
| MGAT5 | -6087.0 | 2955.0 |
| MTMR6 | -5050.0 | 7595.0 |
| NAV2 | -3698.0 | -4133.0 |
| NDUFA2 | 5261.0 | -6155.0 |
| NDUFA3 | 4319.0 | 82.0 |
| NEDD8 | -4578.0 | 7681.0 |
| NEUROG2 | -6666.0 | -2042.0 |
| NR1I3 | 7240.0 | -4497.0 |
| NRIP2 | -3254.0 | -3385.0 |
| NTRK3 | 5960.0 | -263.0 |
| NUMB | -4339.0 | 4601.0 |
| OBSCN | -2429.0 | -3032.0 |
| OR12D3 | 2342.0 | -5876.0 |
| OR7A17 | 1848.0 | -4799.0 |
| OSBPL10 | -2744.0 | -243.0 |
| P2RY4 | -1886.0 | -3292.0 |
| PAX8 | -1678.0 | -3864.0 |
| PCLO | -6586.0 | -2014.0 |
| PCSK2 | -329.0 | -3823.0 |
| PGBD5 | 316.0 | 3543.0 |
| PLEKHA4 | 3114.0 | -4509.0 |
| POMP | -6322.0 | 6114.0 |
| POP1 | -6227.0 | -4247.0 |
| PPP4R3A | -5758.0 | 7453.0 |
| PPP5C | 565.0 | 5319.0 |
| PRKAA2 | -1063.0 | 2375.0 |
| PRSS50 | 4342.5 | -1201.5 |
| PSMF1 | 5087.0 | 4771.0 |
| PTEN | -5726.0 | 8365.0 |
| RAB30 | 6435.0 | 5622.0 |
| RAB3A | -21.0 | -1948.0 |
| RABIF | -2521.0 | -1135.0 |
| RAMP1 | -1058.0 | 6011.0 |
| RCC1 | -3025.0 | -5367.0 |
| RECK | 5456.0 | 4804.0 |
| RENBP | -3824.0 | -6639.0 |
| RGS16 | -3963.0 | 3437.0 |
| RHBDD3 | 5580.0 | -6604.0 |
| RHOA | -5203.0 | 7671.0 |
| S1PR1 | 4311.0 | 7637.0 |
| SERPINF2 | -6756.0 | 961.0 |
| SFPQ | -5196.0 | -4828.0 |
| SIAH1 | 4474.0 | 5949.0 |
| SLC17A4 | -3247.0 | -3993.0 |
| SLC2A2 | 7902.0 | 2301.0 |
| SLC66A3 | 3663.0 | 5856.0 |
| SLC7A2 | 5399.0 | -4500.0 |
| SP1 | 571.0 | 4734.0 |
| SRRD | 1607.0 | -1413.0 |
| STAM2 | 494.0 | 2564.0 |
| SUMO3 | -7259.0 | 7825.0 |
| TFCP2 | 8112.0 | -6489.0 |
| TFF1 | 4927.0 | -5702.0 |
| TGM3 | -987.5 | -1853.5 |
| TJP3 | 7407.0 | -1956.0 |
| TMED7 | -4902.5 | 7760.5 |
| TMOD1 | 1639.0 | -1471.0 |
| TMPRSS2 | 7909.0 | 4409.0 |
| TRIM45 | 4625.0 | -1893.0 |
| TRMT13 | 2744.0 | 786.0 |
| TRPC3 | 4682.0 | 5766.0 |
| TSG101 | -708.0 | 7980.0 |
| TSNAX | 4076.0 | -4048.0 |
| UBA52 | 7488.0 | -4269.0 |
| UPB1 | 7323.0 | 2972.0 |
| USP27X | 2561.0 | 1268.0 |
| ZKSCAN8 | -809.0 | 3321.0 |
| ZNF507 | -6190.0 | 1744.0 |
| ZNF764 | -229.0 | 5915.0 |
Here is the session info with all the versions of packages used.
sessionInfo()## R version 4.0.2 (2020-06-22)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 18.04.5 LTS
##
## Matrix products: default
## BLAS: /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.7.1
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.7.1
##
## locale:
## [1] LC_CTYPE=en_US.UTF-8 LC_NUMERIC=C
## [3] LC_TIME=en_US.UTF-8 LC_COLLATE=en_US.UTF-8
## [5] LC_MONETARY=en_US.UTF-8 LC_MESSAGES=en_US.UTF-8
## [7] LC_PAPER=en_US.UTF-8 LC_NAME=C
## [9] LC_ADDRESS=C LC_TELEPHONE=C
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C
##
## attached base packages:
## [1] parallel stats4 stats graphics grDevices utils datasets
## [8] methods base
##
## other attached packages:
## [1] pkgload_1.1.0 GGally_2.0.0
## [3] beeswarm_0.2.3 gtools_3.8.2
## [5] echarts4r_0.3.2 biomaRt_2.44.1
## [7] R.utils_2.10.1 R.oo_1.24.0
## [9] R.methodsS3_1.8.1 mitch_1.0.8
## [11] eulerr_6.1.0 gplots_3.1.0
## [13] DESeq2_1.28.1 SummarizedExperiment_1.18.2
## [15] DelayedArray_0.14.1 matrixStats_0.57.0
## [17] Biobase_2.48.0 GenomicRanges_1.40.0
## [19] GenomeInfoDb_1.24.2 IRanges_2.22.2
## [21] S4Vectors_0.26.1 BiocGenerics_0.34.0
## [23] reshape2_1.4.4 forcats_0.5.0
## [25] stringr_1.4.0 dplyr_1.0.2
## [27] purrr_0.3.4 readr_1.4.0
## [29] tidyr_1.1.2 tibble_3.0.3
## [31] ggplot2_3.3.2 tidyverse_1.3.0
##
## loaded via a namespace (and not attached):
## [1] colorspace_1.4-1 ellipsis_0.3.1 rprojroot_1.3-2
## [4] XVector_0.28.0 fs_1.5.0 rstudioapi_0.11
## [7] farver_2.0.3 bit64_4.0.5 AnnotationDbi_1.50.3
## [10] fansi_0.4.1 lubridate_1.7.9 xml2_1.3.2
## [13] splines_4.0.2 geneplotter_1.66.0 knitr_1.30
## [16] polyclip_1.10-0 jsonlite_1.7.1 broom_0.7.1
## [19] annotate_1.66.0 dbplyr_1.4.4 shiny_1.5.0
## [22] compiler_4.0.2 httr_1.4.2 backports_1.1.10
## [25] assertthat_0.2.1 Matrix_1.2-18 fastmap_1.0.1
## [28] cli_2.0.2 later_1.1.0.1 prettyunits_1.1.1
## [31] htmltools_0.5.0 tools_4.0.2 gtable_0.3.0
## [34] glue_1.4.2 GenomeInfoDbData_1.2.3 rappdirs_0.3.1
## [37] Rcpp_1.0.5 cellranger_1.1.0 vctrs_0.3.4
## [40] polylabelr_0.2.0 xfun_0.18 testthat_2.3.2
## [43] rvest_0.3.6 mime_0.9 lifecycle_0.2.0
## [46] XML_3.99-0.5 zlibbioc_1.34.0 MASS_7.3-53
## [49] scales_1.1.1 hms_0.5.3 promises_1.1.1
## [52] RColorBrewer_1.1-2 curl_4.3 yaml_2.2.1
## [55] memoise_1.1.0 gridExtra_2.3 reshape_0.8.8
## [58] stringi_1.5.3 RSQLite_2.2.1 highr_0.8
## [61] genefilter_1.70.0 desc_1.2.0 caTools_1.18.0
## [64] BiocParallel_1.22.0 rlang_0.4.7 pkgconfig_2.0.3
## [67] bitops_1.0-6 evaluate_0.14 lattice_0.20-41
## [70] labeling_0.3 htmlwidgets_1.5.2 bit_4.0.4
## [73] tidyselect_1.1.0 plyr_1.8.6 magrittr_1.5
## [76] R6_2.4.1 generics_0.0.2 DBI_1.1.0
## [79] pillar_1.4.6 haven_2.3.1 withr_2.3.0
## [82] survival_3.2-7 RCurl_1.98-1.2 modelr_0.1.8
## [85] crayon_1.3.4 KernSmooth_2.23-17 BiocFileCache_1.12.1
## [88] rmarkdown_2.4 progress_1.2.2 locfit_1.5-9.4
## [91] grid_4.0.2 readxl_1.3.1 blob_1.2.1
## [94] reprex_0.3.0 digest_0.6.25 pbmcapply_1.5.0
## [97] xtable_1.8-4 httpuv_1.5.4 openssl_1.4.3
## [100] munsell_0.5.0 askpass_1.1END of report