Mitch Report

date generated: 2020-10-08

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

##           diabetes       mitoG
## A1CF    -6.9932602  1.51849480
## A3GALT2 -0.4812996  0.04044782
## A4GALT   3.2528398 -0.66706468
## A4GNT    1.2215327  0.29060394
## AAAS     1.7926927 -0.52232889
## AACS    -2.0466443 -0.59825125

Here are some metrics about the input data profile:

Profile metrics

	Profile metrics
num_genes_in_profile	15635
duplicated_genes_present	0
num_profile_genes_in_sets	8750
num_profile_genes_not_in_sets	6885
profile_pearson_correl	-0.26909
profile_spearman_correl	-0.21206

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used: GMT file of genesets: ReactomePathways.gmt

Gene sets metrics

	Gene sets metrics
num_genesets	2408
num_genesets_excluded	1006
num_genesets_included	1402

Gene sets by quadrant

Number of significant gene sets (FDR<0.05)= 426

Interactive enrichment scatterplot

All sets with FDR<0.05. Try hovering over the points.

Top N sets irrespective of FDR. Try hovering over the points.

A heatmap of S values for top results

A plot of effect size versus significance

Significance is the -log2(p.adjustMANOVA) and effect size is the s.dist which is the hypotenuse of the s scores.

Results table

Top N= 50 gene sets

set	setSize	pMANOVA	p.adjustMANOVA	s.dist	s.diabetes	s.mitoG	p.diabetes	p.mitoG
Olfactory Signaling Pathway	209	2.09e-38	2.93e-35	0.4770	-0.21600	-0.4250	7.91e-08	3.03e-26
Infectious disease	693	4.47e-24	3.13e-21	0.2390	-0.05480	0.2320	1.46e-02	3.51e-25
G alpha (s) signalling events	298	1.03e-23	4.83e-21	0.3100	-0.16800	-0.2610	6.21e-07	1.09e-14
Metabolism of proteins	1749	2.08e-21	7.29e-19	0.1530	-0.06580	0.1380	7.12e-06	4.61e-21
Immune System	1784	4.99e-20	1.40e-17	0.1460	-0.06310	0.1320	1.37e-05	9.46e-20
Innate Immune System	893	2.85e-18	6.66e-16	0.1890	-0.06990	0.1750	4.43e-04	1.05e-18
Vesicle-mediated transport	622	2.63e-17	5.27e-15	0.2150	-0.06290	0.2050	7.76e-03	3.39e-18
Adaptive Immune System	663	3.43e-17	6.01e-15	0.2190	-0.14100	0.1670	6.49e-10	2.84e-13
Disease	1333	8.84e-17	1.38e-14	0.1430	-0.02170	0.1420	1.89e-01	9.26e-18
Metabolism of RNA	629	2.03e-14	2.85e-12	0.2010	-0.09310	0.1780	7.40e-05	3.92e-14
Hemostasis	547	1.75e-13	2.22e-11	0.1900	-0.00704	0.1890	7.79e-01	4.52e-14
Nervous system development	494	2.15e-13	2.52e-11	0.2010	-0.01980	0.2000	4.53e-01	3.27e-14
Axon guidance	472	1.93e-12	2.08e-10	0.1970	-0.01710	0.1960	5.25e-01	3.19e-13
Developmental Biology	770	5.30e-12	5.20e-10	0.1460	0.01980	0.1450	3.52e-01	1.16e-11
Membrane Trafficking	570	5.56e-12	5.20e-10	0.1860	-0.06420	0.1750	9.14e-03	1.15e-12
Fc epsilon receptor (FCERI) signaling	143	6.39e-12	5.60e-10	0.3780	-0.19800	0.3220	4.42e-05	3.24e-11
Signaling by the B Cell Receptor (BCR)	123	8.95e-12	7.37e-10	0.4060	-0.22700	0.3370	1.34e-05	1.17e-10
rRNA processing	176	9.46e-12	7.37e-10	0.2960	0.04330	0.2920	3.22e-01	2.31e-11
Post-translational protein modification	1238	1.16e-11	8.56e-10	0.1320	-0.06850	0.1120	6.11e-05	4.99e-11
Translation	256	4.93e-11	3.40e-09	0.2630	-0.08730	0.2480	1.65e-02	9.09e-12
Cap-dependent Translation Initiation	85	5.33e-11	3.40e-09	0.3900	0.17300	0.3500	5.89e-03	2.50e-08
Eukaryotic Translation Initiation	85	5.33e-11	3.40e-09	0.3900	0.17300	0.3500	5.89e-03	2.50e-08
Formation of a pool of free 40S subunits	67	1.80e-10	1.10e-08	0.4210	0.26100	0.3300	2.19e-04	2.97e-06
Extracellular matrix organization	252	2.09e-10	1.22e-08	0.2250	0.06980	0.2140	5.70e-02	4.94e-09
Metabolism	1871	2.52e-10	1.41e-08	0.0841	0.06640	0.0516	2.99e-06	2.85e-04
GTP hydrolysis and joining of the 60S ribosomal subunit	78	3.66e-10	1.97e-08	0.3900	0.17500	0.3490	7.75e-03	1.00e-07
L13a-mediated translational silencing of Ceruloplasmin expression	77	7.06e-10	3.66e-08	0.3860	0.18200	0.3400	5.86e-03	2.50e-07
Signaling by Interleukins	381	7.80e-10	3.90e-08	0.2050	-0.07690	0.1900	1.03e-02	2.09e-10
Elastic fibre formation	37	1.43e-09	6.91e-08	0.5490	0.23400	0.4970	1.37e-02	1.70e-07
Regulation of actin dynamics for phagocytic cup formation	76	1.57e-09	7.15e-08	0.4340	-0.09740	0.4220	1.43e-01	1.93e-10
Signaling by ROBO receptors	177	1.58e-09	7.15e-08	0.2810	-0.04720	0.2770	2.80e-01	2.01e-10
Cellular responses to external stimuli	470	1.78e-09	7.78e-08	0.1670	0.00238	0.1670	9.30e-01	6.23e-10
Neutrophil degranulation	416	2.06e-09	8.77e-08	0.1890	-0.05580	0.1800	5.19e-02	3.10e-10
Major pathway of rRNA processing in the nucleolus and cytosol	145	2.19e-09	9.05e-08	0.2870	0.05020	0.2820	2.98e-01	4.49e-09
Defective CFTR causes cystic fibrosis	60	2.63e-09	1.05e-07	0.5100	-0.42900	0.2760	8.76e-09	2.21e-04
Cell surface interactions at the vascular wall	132	3.12e-09	1.22e-07	0.3150	-0.03270	0.3140	5.17e-01	4.94e-10
Cellular responses to stress	465	3.24e-09	1.23e-07	0.1670	-0.00236	0.1660	9.31e-01	8.88e-10
Apoptosis	164	4.27e-09	1.57e-07	0.2920	-0.08270	0.2800	6.80e-02	6.17e-10
Binding and Uptake of Ligands by Scavenger Receptors	54	4.40e-09	1.58e-07	0.4860	-0.04270	0.4840	5.88e-01	7.54e-10
FCERI mediated NF-kB activation	91	4.57e-09	1.60e-07	0.4130	-0.25800	0.3220	2.16e-05	1.10e-07
rRNA processing in the nucleus and cytosol	154	7.37e-09	2.52e-07	0.2720	0.03750	0.2690	4.23e-01	8.49e-09
Influenza Viral RNA Transcription and Replication	103	8.50e-09	2.84e-07	0.3100	0.24800	0.1850	1.35e-05	1.17e-03
Diseases of signal transduction by growth factor receptors and second messengers	362	9.24e-09	3.01e-07	0.2010	-0.09650	0.1770	1.67e-03	8.66e-09
HIV Infection	222	1.07e-08	3.42e-07	0.2520	-0.10600	0.2290	6.37e-03	4.51e-09
The citric acid (TCA) cycle and respiratory electron transport	168	1.10e-08	3.43e-07	0.2410	0.16200	0.1780	2.88e-04	7.32e-05
Programmed Cell Death	175	1.23e-08	3.74e-07	0.2720	-0.06160	0.2650	1.61e-01	1.59e-09
Cytokine Signaling in Immune system	736	1.47e-08	4.37e-07	0.1400	-0.06040	0.1260	5.56e-03	6.86e-09
Hh mutants that don't undergo autocatalytic processing are degraded by ERAD	55	1.92e-08	5.61e-07	0.5060	-0.42400	0.2750	5.17e-08	4.26e-04
Viral mRNA Translation	56	2.25e-08	6.45e-07	0.4070	0.31100	0.2630	5.77e-05	6.53e-04
Antigen processing-Cross presentation	91	2.30e-08	6.45e-07	0.3940	-0.31600	0.2360	1.96e-07	1.03e-04

---

Results (complete table)

Click HERE to show results for all gene sets

Complete results

set	setSize	pMANOVA	p.adjustMANOVA	s.dist	s.diabetes	s.mitoG	p.diabetes	p.mitoG
Olfactory Signaling Pathway	209	2.09e-38	2.93e-35	0.47700	-2.16e-01	-4.25e-01	7.91e-08	3.03e-26
Infectious disease	693	4.47e-24	3.13e-21	0.23900	-5.48e-02	2.32e-01	1.46e-02	3.51e-25
G alpha (s) signalling events	298	1.03e-23	4.83e-21	0.31000	-1.68e-01	-2.61e-01	6.21e-07	1.09e-14
Metabolism of proteins	1749	2.08e-21	7.29e-19	0.15300	-6.58e-02	1.38e-01	7.12e-06	4.61e-21
Immune System	1784	4.99e-20	1.40e-17	0.14600	-6.31e-02	1.32e-01	1.37e-05	9.46e-20
Innate Immune System	893	2.85e-18	6.66e-16	0.18900	-6.99e-02	1.75e-01	4.43e-04	1.05e-18
Vesicle-mediated transport	622	2.63e-17	5.27e-15	0.21500	-6.29e-02	2.05e-01	7.76e-03	3.39e-18
Adaptive Immune System	663	3.43e-17	6.01e-15	0.21900	-1.41e-01	1.67e-01	6.49e-10	2.84e-13
Disease	1333	8.84e-17	1.38e-14	0.14300	-2.17e-02	1.42e-01	1.89e-01	9.26e-18
Metabolism of RNA	629	2.03e-14	2.85e-12	0.20100	-9.31e-02	1.78e-01	7.40e-05	3.92e-14
Hemostasis	547	1.75e-13	2.22e-11	0.19000	-7.04e-03	1.89e-01	7.79e-01	4.52e-14
Nervous system development	494	2.15e-13	2.52e-11	0.20100	-1.98e-02	2.00e-01	4.53e-01	3.27e-14
Axon guidance	472	1.93e-12	2.08e-10	0.19700	-1.71e-02	1.96e-01	5.25e-01	3.19e-13
Developmental Biology	770	5.30e-12	5.20e-10	0.14600	1.98e-02	1.45e-01	3.52e-01	1.16e-11
Membrane Trafficking	570	5.56e-12	5.20e-10	0.18600	-6.42e-02	1.75e-01	9.14e-03	1.15e-12
Fc epsilon receptor (FCERI) signaling	143	6.39e-12	5.60e-10	0.37800	-1.98e-01	3.22e-01	4.42e-05	3.24e-11
Signaling by the B Cell Receptor (BCR)	123	8.95e-12	7.37e-10	0.40600	-2.27e-01	3.37e-01	1.34e-05	1.17e-10
rRNA processing	176	9.46e-12	7.37e-10	0.29600	4.33e-02	2.92e-01	3.22e-01	2.31e-11
Post-translational protein modification	1238	1.16e-11	8.56e-10	0.13200	-6.85e-02	1.12e-01	6.11e-05	4.99e-11
Translation	256	4.93e-11	3.40e-09	0.26300	-8.73e-02	2.48e-01	1.65e-02	9.09e-12
Cap-dependent Translation Initiation	85	5.33e-11	3.40e-09	0.39000	1.73e-01	3.50e-01	5.89e-03	2.50e-08
Eukaryotic Translation Initiation	85	5.33e-11	3.40e-09	0.39000	1.73e-01	3.50e-01	5.89e-03	2.50e-08
Formation of a pool of free 40S subunits	67	1.80e-10	1.10e-08	0.42100	2.61e-01	3.30e-01	2.19e-04	2.97e-06
Extracellular matrix organization	252	2.09e-10	1.22e-08	0.22500	6.98e-02	2.14e-01	5.70e-02	4.94e-09
Metabolism	1871	2.52e-10	1.41e-08	0.08410	6.64e-02	5.16e-02	2.99e-06	2.85e-04
GTP hydrolysis and joining of the 60S ribosomal subunit	78	3.66e-10	1.97e-08	0.39000	1.75e-01	3.49e-01	7.75e-03	1.00e-07
L13a-mediated translational silencing of Ceruloplasmin expression	77	7.06e-10	3.66e-08	0.38600	1.82e-01	3.40e-01	5.86e-03	2.50e-07
Signaling by Interleukins	381	7.80e-10	3.90e-08	0.20500	-7.69e-02	1.90e-01	1.03e-02	2.09e-10
Elastic fibre formation	37	1.43e-09	6.91e-08	0.54900	2.34e-01	4.97e-01	1.37e-02	1.70e-07
Regulation of actin dynamics for phagocytic cup formation	76	1.57e-09	7.15e-08	0.43400	-9.74e-02	4.22e-01	1.43e-01	1.93e-10
Signaling by ROBO receptors	177	1.58e-09	7.15e-08	0.28100	-4.72e-02	2.77e-01	2.80e-01	2.01e-10
Cellular responses to external stimuli	470	1.78e-09	7.78e-08	0.16700	2.38e-03	1.67e-01	9.30e-01	6.23e-10
Neutrophil degranulation	416	2.06e-09	8.77e-08	0.18900	-5.58e-02	1.80e-01	5.19e-02	3.10e-10
Major pathway of rRNA processing in the nucleolus and cytosol	145	2.19e-09	9.05e-08	0.28700	5.02e-02	2.82e-01	2.98e-01	4.49e-09
Defective CFTR causes cystic fibrosis	60	2.63e-09	1.05e-07	0.51000	-4.29e-01	2.76e-01	8.76e-09	2.21e-04
Cell surface interactions at the vascular wall	132	3.12e-09	1.22e-07	0.31500	-3.27e-02	3.14e-01	5.17e-01	4.94e-10
Cellular responses to stress	465	3.24e-09	1.23e-07	0.16700	-2.36e-03	1.66e-01	9.31e-01	8.88e-10
Apoptosis	164	4.27e-09	1.57e-07	0.29200	-8.27e-02	2.80e-01	6.80e-02	6.17e-10
Binding and Uptake of Ligands by Scavenger Receptors	54	4.40e-09	1.58e-07	0.48600	-4.27e-02	4.84e-01	5.88e-01	7.54e-10
FCERI mediated NF-kB activation	91	4.57e-09	1.60e-07	0.41300	-2.58e-01	3.22e-01	2.16e-05	1.10e-07
rRNA processing in the nucleus and cytosol	154	7.37e-09	2.52e-07	0.27200	3.75e-02	2.69e-01	4.23e-01	8.49e-09
Influenza Viral RNA Transcription and Replication	103	8.50e-09	2.84e-07	0.31000	2.48e-01	1.85e-01	1.35e-05	1.17e-03
Diseases of signal transduction by growth factor receptors and second messengers	362	9.24e-09	3.01e-07	0.20100	-9.65e-02	1.77e-01	1.67e-03	8.66e-09
HIV Infection	222	1.07e-08	3.42e-07	0.25200	-1.06e-01	2.29e-01	6.37e-03	4.51e-09
The citric acid (TCA) cycle and respiratory electron transport	168	1.10e-08	3.43e-07	0.24100	1.62e-01	1.78e-01	2.88e-04	7.32e-05
Programmed Cell Death	175	1.23e-08	3.74e-07	0.27200	-6.16e-02	2.65e-01	1.61e-01	1.59e-09
Cytokine Signaling in Immune system	736	1.47e-08	4.37e-07	0.14000	-6.04e-02	1.26e-01	5.56e-03	6.86e-09
Hh mutants that don't undergo autocatalytic processing are degraded by ERAD	55	1.92e-08	5.61e-07	0.50600	-4.24e-01	2.75e-01	5.17e-08	4.26e-04
Viral mRNA Translation	56	2.25e-08	6.45e-07	0.40700	3.11e-01	2.63e-01	5.77e-05	6.53e-04
Antigen processing-Cross presentation	91	2.30e-08	6.45e-07	0.39400	-3.16e-01	2.36e-01	1.96e-07	1.03e-04
Influenza Infection	119	2.42e-08	6.64e-07	0.28200	1.51e-01	2.38e-01	4.50e-03	7.67e-06
Peptide chain elongation	55	2.51e-08	6.75e-07	0.41000	3.17e-01	2.60e-01	4.79e-05	8.52e-04
Cell Cycle, Mitotic	488	2.55e-08	6.75e-07	0.14700	3.31e-02	1.43e-01	2.13e-01	7.29e-08
TCR signaling	109	2.92e-08	7.58e-07	0.35800	-2.85e-01	2.16e-01	2.73e-07	9.70e-05
Response of EIF2AK4 (GCN2) to amino acid deficiency	68	3.40e-08	8.67e-07	0.36500	2.38e-01	2.77e-01	6.94e-04	7.69e-05
Asparagine N-linked glycosylation	265	4.38e-08	1.10e-06	0.22800	-1.80e-01	1.40e-01	4.83e-07	8.72e-05
Formation of the ternary complex, and subsequently, the 43S complex	36	4.74e-08	1.17e-06	0.51000	1.96e-01	4.70e-01	4.20e-02	1.04e-06
FCGR3A-mediated phagocytosis	74	5.10e-08	1.19e-06	0.39800	-8.08e-02	3.90e-01	2.30e-01	6.83e-09
Leishmania phagocytosis	74	5.10e-08	1.19e-06	0.39800	-8.08e-02	3.90e-01	2.30e-01	6.83e-09
Parasite infection	74	5.10e-08	1.19e-06	0.39800	-8.08e-02	3.90e-01	2.30e-01	6.83e-09
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.	120	5.69e-08	1.31e-06	0.27400	2.38e-01	1.37e-01	6.91e-06	9.66e-03
Hedgehog ligand biogenesis	64	6.79e-08	1.53e-06	0.45000	-3.88e-01	2.28e-01	8.27e-08	1.61e-03
SARS-CoV Infections	139	7.13e-08	1.59e-06	0.30700	-1.66e-01	2.58e-01	7.62e-04	1.50e-07
AUF1 (hnRNP D0) binds and destabilizes mRNA	54	7.27e-08	1.59e-06	0.49500	-3.83e-01	3.14e-01	1.12e-06	6.62e-05
Fcgamma receptor (FCGR) dependent phagocytosis	100	8.78e-08	1.89e-06	0.34800	-1.24e-01	3.25e-01	3.17e-02	1.96e-08
Protein ubiquitination	65	9.55e-08	2.03e-06	0.44600	-2.60e-01	3.62e-01	2.88e-04	4.47e-07
Regulation of expression of SLITs and ROBOs	134	1.34e-07	2.81e-06	0.28200	-3.36e-02	2.80e-01	5.03e-01	2.14e-08
Regulation of mRNA stability by proteins that bind AU-rich elements	87	1.41e-07	2.91e-06	0.38400	-2.73e-01	2.70e-01	1.11e-05	1.37e-05
Signaling by NOTCH4	79	1.44e-07	2.93e-06	0.39900	-2.26e-01	3.28e-01	5.17e-04	4.53e-07
Eukaryotic Translation Elongation	58	1.52e-07	3.04e-06	0.37800	2.82e-01	2.52e-01	2.08e-04	9.11e-04
Potential therapeutics for SARS	78	1.54e-07	3.04e-06	0.39600	-1.94e-01	3.46e-01	3.12e-03	1.32e-07
ER-Phagosome pathway	78	1.58e-07	3.07e-06	0.40000	-3.32e-01	2.23e-01	4.14e-07	6.64e-04
Negative regulation of NOTCH4 signaling	52	1.64e-07	3.15e-06	0.49300	-3.49e-01	3.48e-01	1.31e-05	1.40e-05
tRNA processing in the mitochondrion	18	1.74e-07	3.29e-06	0.71800	1.16e-01	7.09e-01	3.95e-01	1.91e-07
GPCR downstream signalling	710	1.85e-07	3.45e-06	0.11000	-7.53e-02	-7.96e-02	6.84e-04	3.30e-04
Eukaryotic Translation Termination	60	2.07e-07	3.82e-06	0.36800	2.69e-01	2.51e-01	3.20e-04	7.76e-04
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S	44	2.16e-07	3.94e-06	0.44600	1.30e-01	4.27e-01	1.37e-01	9.62e-07
Cell Cycle	607	2.46e-07	4.42e-06	0.12100	4.11e-02	1.14e-01	8.59e-02	1.95e-06
Selenocysteine synthesis	60	2.60e-07	4.62e-06	0.36600	2.92e-01	2.20e-01	9.03e-05	3.16e-03
Ribosomal scanning and start codon recognition	43	3.35e-07	5.68e-06	0.44700	1.17e-01	4.31e-01	1.85e-01	9.86e-07
RHO GTPase Effectors	246	3.36e-07	5.68e-06	0.19700	6.60e-03	1.96e-01	8.59e-01	1.19e-07
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	81	3.38e-07	5.68e-06	0.31900	1.31e-01	2.91e-01	4.24e-02	6.16e-06
Nonsense-Mediated Decay (NMD)	81	3.38e-07	5.68e-06	0.31900	1.31e-01	2.91e-01	4.24e-02	6.16e-06
Translation initiation complex formation	43	3.40e-07	5.68e-06	0.44600	1.19e-01	4.30e-01	1.77e-01	1.06e-06
Regulation of PTEN stability and activity	68	3.60e-07	5.95e-06	0.42100	-2.90e-01	3.04e-01	3.48e-05	1.45e-05
Leishmania infection	204	3.73e-07	6.08e-06	0.22400	-3.74e-02	2.21e-01	3.59e-01	5.45e-08
Platelet activation, signaling and aggregation	242	3.93e-07	6.34e-06	0.21200	-6.71e-02	2.02e-01	7.26e-02	7.04e-08
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	103	3.99e-07	6.35e-06	0.34000	-2.69e-01	2.08e-01	2.51e-06	2.73e-04
Hh mutants abrogate ligand secretion	58	4.04e-07	6.36e-06	0.44800	-3.77e-01	2.43e-01	7.04e-07	1.37e-03
Downstream signaling events of B Cell Receptor (BCR)	80	4.41e-07	6.87e-06	0.38500	-2.60e-01	2.84e-01	5.79e-05	1.14e-05
Cross-presentation of soluble exogenous antigens (endosomes)	48	4.51e-07	6.95e-06	0.49400	-3.91e-01	3.03e-01	2.82e-06	2.83e-04
Downstream TCR signaling	88	4.66e-07	7.10e-06	0.36500	-2.92e-01	2.19e-01	2.21e-06	3.98e-04
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)	103	5.36e-07	8.07e-06	0.27700	1.27e-01	2.46e-01	2.62e-02	1.64e-05
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	62	6.74e-07	1.00e-05	0.34800	2.15e-01	2.74e-01	3.36e-03	1.94e-04
Scavenging of heme from plasma	29	6.98e-07	1.03e-05	0.57400	-7.35e-02	5.69e-01	4.94e-01	1.12e-07
Activation of NF-kappaB in B cells	66	8.09e-07	1.18e-05	0.41400	-3.19e-01	2.65e-01	7.64e-06	2.02e-04
Regulation of Apoptosis	52	8.17e-07	1.18e-05	0.46400	-3.78e-01	2.69e-01	2.41e-06	8.05e-04
SRP-dependent cotranslational protein targeting to membrane	79	9.05e-07	1.29e-05	0.32800	3.60e-02	3.26e-01	5.81e-01	5.45e-07
CLEC7A (Dectin-1) signaling	97	9.51e-07	1.34e-05	0.34000	-2.23e-01	2.57e-01	1.54e-04	1.19e-05
SLC-mediated transmembrane transport	217	9.57e-07	1.34e-05	0.22800	1.44e-01	-1.77e-01	2.56e-04	7.60e-06
C-type lectin receptors (CLRs)	127	9.77e-07	1.36e-05	0.29800	-2.08e-01	2.13e-01	5.08e-05	3.52e-05
S Phase	158	9.88e-07	1.36e-05	0.24900	-5.55e-02	2.43e-01	2.30e-01	1.46e-07
Regulation of RUNX3 expression and activity	53	1.05e-06	1.43e-05	0.45800	-3.45e-01	3.02e-01	1.41e-05	1.46e-04
Glucose metabolism	85	1.09e-06	1.47e-05	0.30300	2.87e-01	9.66e-02	4.92e-06	1.24e-01
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis	54	1.21e-06	1.62e-05	0.45000	-3.54e-01	2.79e-01	7.03e-06	3.88e-04
Signaling by Rho GTPases	370	1.31e-06	1.73e-05	0.15400	1.49e-03	1.54e-01	9.61e-01	3.86e-07
Vif-mediated degradation of APOBEC3G	52	1.47e-06	1.92e-05	0.45700	-3.48e-01	2.96e-01	1.45e-05	2.21e-04
Signaling by Receptor Tyrosine Kinases	451	1.49e-06	1.94e-05	0.14900	-4.34e-02	1.42e-01	1.16e-01	2.51e-07
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	44	1.52e-06	1.94e-05	0.47700	-1.75e-01	4.43e-01	4.50e-02	3.60e-07
Degradation of GLI1 by the proteasome	58	1.52e-06	1.94e-05	0.42900	-3.52e-01	2.45e-01	3.48e-06	1.27e-03
Regulation of RAS by GAPs	67	1.54e-06	1.94e-05	0.40200	-2.85e-01	2.85e-01	5.67e-05	5.63e-05
NIK-->noncanonical NF-kB signaling	58	1.68e-06	2.11e-05	0.42900	-3.37e-01	2.66e-01	8.99e-06	4.61e-04
Role of LAT2/NTAL/LAB on calcium mobilization	29	1.70e-06	2.11e-05	0.58900	-2.44e-01	5.37e-01	2.30e-02	5.67e-07
Regulation of activated PAK-2p34 by proteasome mediated degradation	49	1.79e-06	2.20e-05	0.46500	-3.72e-01	2.80e-01	6.78e-06	7.01e-04
Signaling by GPCR	758	1.82e-06	2.22e-05	0.09810	-6.56e-02	-7.30e-02	2.27e-03	6.87e-04
Degradation of GLI2 by the proteasome	58	1.94e-06	2.35e-05	0.42600	-3.46e-01	2.49e-01	5.35e-06	1.05e-03
Respiratory electron transport	99	2.09e-06	2.50e-05	0.26600	2.21e-01	1.48e-01	1.44e-04	1.12e-02
Apoptotic execution phase	49	2.16e-06	2.56e-05	0.38200	1.66e-01	3.44e-01	4.51e-02	3.10e-05
FCERI mediated MAPK activation	45	2.48e-06	2.92e-05	0.44900	-1.01e-01	4.38e-01	2.39e-01	3.78e-07
GLI3 is processed to GLI3R by the proteasome	58	2.66e-06	3.11e-05	0.42200	-3.35e-01	2.55e-01	1.01e-05	7.70e-04
Attenuation phase	22	2.93e-06	3.39e-05	0.67300	-5.80e-01	3.41e-01	2.45e-06	5.65e-03
Classical antibody-mediated complement activation	22	3.07e-06	3.53e-05	0.64400	-1.77e-01	6.19e-01	1.50e-01	5.07e-07
HSP90 chaperone cycle for steroid hormone receptors (SHR)	37	3.12e-06	3.56e-05	0.52200	-2.96e-01	4.30e-01	1.84e-03	6.00e-06
FCERI mediated Ca+2 mobilization	44	3.15e-06	3.56e-05	0.45700	-1.35e-01	4.36e-01	1.23e-01	5.46e-07
Dectin-1 mediated noncanonical NF-kB signaling	61	3.24e-06	3.64e-05	0.40900	-3.19e-01	2.56e-01	1.68e-05	5.56e-04
Vpu mediated degradation of CD4	51	3.49e-06	3.89e-05	0.44400	-3.55e-01	2.67e-01	1.15e-05	9.65e-04
Prefoldin mediated transfer of substrate to CCT/TriC	25	3.93e-06	4.34e-05	0.63400	-4.67e-01	4.30e-01	5.37e-05	2.00e-04
Gluconeogenesis	30	4.13e-06	4.53e-05	0.49300	4.82e-01	1.01e-01	4.87e-06	3.37e-01
EPHB-mediated forward signaling	34	4.22e-06	4.59e-05	0.52000	-1.83e-01	4.86e-01	6.46e-02	9.30e-07
Platelet degranulation	118	5.21e-06	5.61e-05	0.25600	4.45e-03	2.56e-01	9.34e-01	1.57e-06
Post-translational protein phosphorylation	90	5.27e-06	5.64e-05	0.27200	1.22e-01	2.43e-01	4.51e-02	7.00e-05
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding	27	5.89e-06	6.25e-05	0.60100	-4.38e-01	4.10e-01	8.05e-05	2.23e-04
Molecules associated with elastic fibres	27	6.32e-06	6.67e-05	0.50200	1.53e-01	4.78e-01	1.69e-01	1.73e-05
M Phase	348	6.40e-06	6.69e-05	0.14900	1.48e-03	1.49e-01	9.62e-01	1.85e-06
Signal Transduction	2201	6.59e-06	6.84e-05	0.07110	-4.34e-02	5.63e-02	1.07e-03	2.25e-05
Transport of inorganic cations/anions and amino acids/oligopeptides	97	6.76e-06	6.97e-05	0.31500	2.00e-01	-2.43e-01	6.68e-04	3.49e-05
Response to elevated platelet cytosolic Ca2+	123	8.33e-06	8.53e-05	0.24900	-1.02e-02	2.49e-01	8.45e-01	1.90e-06
Mitotic Metaphase and Anaphase	221	9.70e-06	9.85e-05	0.19700	-6.54e-02	1.86e-01	9.48e-02	1.97e-06
Degradation of AXIN	54	9.93e-06	1.00e-04	0.41500	-3.17e-01	2.68e-01	5.61e-05	6.66e-04
Platelet homeostasis	79	1.03e-05	1.03e-04	0.27800	1.60e-01	2.28e-01	1.40e-02	4.65e-04
Mitotic Anaphase	220	1.05e-05	1.04e-04	0.19700	-6.45e-02	1.86e-01	1.00e-01	2.09e-06
Toll-like Receptor Cascades	138	1.08e-05	1.06e-04	0.24000	-4.42e-02	2.36e-01	3.71e-01	1.74e-06
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A	51	1.28e-05	1.23e-04	0.42000	-3.41e-01	2.45e-01	2.47e-05	2.50e-03
p53-Independent DNA Damage Response	51	1.28e-05	1.23e-04	0.42000	-3.41e-01	2.45e-01	2.47e-05	2.50e-03
p53-Independent G1/S DNA damage checkpoint	51	1.28e-05	1.23e-04	0.42000	-3.41e-01	2.45e-01	2.47e-05	2.50e-03
Transcriptional regulation by RUNX3	93	1.28e-05	1.23e-04	0.30900	-1.59e-01	2.65e-01	8.24e-03	1.02e-05
Ubiquitin-dependent degradation of Cyclin D	51	1.40e-05	1.34e-04	0.42000	-3.32e-01	2.56e-01	4.04e-05	1.57e-03
Class I MHC mediated antigen processing & presentation	341	1.52e-05	1.44e-04	0.16400	-1.20e-01	1.11e-01	1.39e-04	4.44e-04
Creation of C4 and C2 activators	26	1.72e-05	1.62e-04	0.54200	-1.12e-01	5.31e-01	3.24e-01	2.82e-06
Regulation of ornithine decarboxylase (ODC)	50	1.73e-05	1.62e-04	0.41800	-3.45e-01	2.35e-01	2.45e-05	4.01e-03
SCF-beta-TrCP mediated degradation of Emi1	54	1.79e-05	1.66e-04	0.40200	-3.26e-01	2.37e-01	3.52e-05	2.65e-03
Anti-inflammatory response favouring Leishmania parasite infection	125	1.81e-05	1.66e-04	0.25500	-8.98e-02	2.39e-01	8.33e-02	4.05e-06
Leishmania parasite growth and survival	125	1.81e-05	1.66e-04	0.25500	-8.98e-02	2.39e-01	8.33e-02	4.05e-06
PIP3 activates AKT signaling	248	1.84e-05	1.67e-04	0.18800	-1.04e-01	1.57e-01	5.07e-03	2.19e-05
FCGR activation	28	1.93e-05	1.74e-04	0.55400	-3.01e-01	4.65e-01	5.85e-03	2.08e-05
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	35	2.06e-05	1.85e-04	0.47600	-4.49e-01	1.59e-01	4.28e-06	1.04e-01
Transcriptional Regulation by TP53	340	2.37e-05	2.12e-04	0.13700	2.81e-02	1.34e-01	3.75e-01	2.26e-05
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha	64	2.44e-05	2.17e-04	0.36700	-2.57e-01	2.62e-01	3.76e-04	2.98e-04
Synthesis of active ubiquitin: roles of E1 and E2 enzymes	30	2.72e-05	2.40e-04	0.52900	-3.13e-01	4.26e-01	2.96e-03	5.29e-05
Autodegradation of the E3 ubiquitin ligase COP1	50	2.89e-05	2.53e-04	0.40900	-3.32e-01	2.39e-01	4.99e-05	3.49e-03
G1/S Transition	128	2.93e-05	2.55e-04	0.24000	-5.43e-02	2.34e-01	2.89e-01	4.92e-06
Separation of Sister Chromatids	166	2.96e-05	2.56e-04	0.22100	-1.03e-01	1.96e-01	2.21e-02	1.38e-05
Mitotic G1 phase and G1/S transition	145	3.02e-05	2.60e-04	0.22400	-4.32e-02	2.20e-01	3.70e-01	5.07e-06
Signaling by VEGF	101	3.08e-05	2.63e-04	0.27800	-1.06e-01	2.57e-01	6.65e-02	7.95e-06
Intracellular signaling by second messengers	286	3.22e-05	2.74e-04	0.16800	-7.54e-02	1.50e-01	2.87e-02	1.30e-05
Formation of tubulin folding intermediates by CCT/TriC	20	3.45e-05	2.91e-04	0.64200	-5.09e-01	3.90e-01	8.09e-05	2.50e-03
RNA Polymerase II Transcription	1047	3.78e-05	3.14e-04	0.08960	-4.11e-02	7.96e-02	2.59e-02	1.65e-05
Assembly of the pre-replicative complex	67	3.78e-05	3.14e-04	0.34800	-2.01e-01	2.84e-01	4.37e-03	5.74e-05
Integrin cell surface interactions	58	3.79e-05	3.14e-04	0.33100	1.71e-02	3.31e-01	8.22e-01	1.32e-05
Folding of actin by CCT/TriC	10	3.94e-05	3.25e-04	0.88100	-7.91e-01	3.89e-01	1.49e-05	3.34e-02
MAPK6/MAPK4 signaling	85	4.15e-05	3.40e-04	0.31000	-2.02e-01	2.35e-01	1.33e-03	1.76e-04
E3 ubiquitin ligases ubiquitinate target proteins	45	4.23e-05	3.45e-04	0.42200	-2.39e-01	3.48e-01	5.51e-03	5.46e-05
ESR-mediated signaling	160	4.48e-05	3.63e-04	0.20800	-3.34e-02	2.05e-01	4.67e-01	7.84e-06
EPH-Ephrin signaling	89	4.54e-05	3.66e-04	0.26800	5.55e-04	2.68e-01	9.93e-01	1.25e-05
Orc1 removal from chromatin	69	4.77e-05	3.82e-04	0.33900	-1.96e-01	2.77e-01	4.91e-03	6.91e-05
CDT1 association with the CDC6:ORC:origin complex	58	4.79e-05	3.82e-04	0.37300	-2.49e-01	2.78e-01	1.07e-03	2.58e-04
Deubiquitination	236	5.21e-05	4.13e-04	0.18500	-1.15e-01	1.44e-01	2.33e-03	1.42e-04
Selenoamino acid metabolism	83	5.28e-05	4.16e-04	0.25100	1.55e-01	1.97e-01	1.44e-02	1.94e-03
MAPK family signaling cascades	291	5.33e-05	4.17e-04	0.16500	-9.31e-02	1.37e-01	6.45e-03	6.36e-05
Cell Cycle Checkpoints	249	5.47e-05	4.26e-04	0.16100	-7.59e-03	1.61e-01	8.37e-01	1.25e-05
Degradation of beta-catenin by the destruction complex	84	6.09e-05	4.68e-04	0.30500	-1.83e-01	2.43e-01	3.70e-03	1.16e-04
Establishment of Sister Chromatid Cohesion	11	6.11e-05	4.68e-04	0.83800	-4.88e-01	6.81e-01	5.03e-03	9.08e-05
Host Interactions of HIV factors	126	6.12e-05	4.68e-04	0.24900	-1.52e-01	1.97e-01	3.21e-03	1.31e-04
Cellular response to hypoxia	73	6.17e-05	4.70e-04	0.32700	-2.59e-01	1.99e-01	1.28e-04	3.34e-03
Regulation of RUNX2 expression and activity	70	6.64e-05	5.00e-04	0.33300	-2.59e-01	2.10e-01	1.84e-04	2.43e-03
The role of GTSE1 in G2/M progression after G2 checkpoint	59	6.68e-05	5.00e-04	0.36300	-2.72e-01	2.40e-01	2.96e-04	1.44e-03
HIV Life Cycle	145	6.69e-05	5.00e-04	0.21100	-2.10e-02	2.10e-01	6.63e-01	1.32e-05
VEGFA-VEGFR2 Pathway	93	6.73e-05	5.00e-04	0.27900	-1.10e-01	2.57e-01	6.78e-02	1.86e-05
Transport to the Golgi and subsequent modification	153	6.74e-05	5.00e-04	0.22200	-1.06e-01	1.95e-01	2.38e-02	3.35e-05
ER to Golgi Anterograde Transport	126	7.20e-05	5.31e-04	0.24500	-1.27e-01	2.09e-01	1.38e-02	5.18e-05
Signaling by Hedgehog	133	7.99e-05	5.87e-04	0.23500	-2.07e-01	1.12e-01	3.83e-05	2.61e-02
Cyclin E associated events during G1/S transition	81	8.14e-05	5.94e-04	0.30300	-1.60e-01	2.57e-01	1.27e-02	6.33e-05
ABC transporter disorders	73	8.44e-05	6.13e-04	0.31300	-2.85e-01	1.29e-01	2.61e-05	5.68e-02
PTEN Regulation	139	8.95e-05	6.47e-04	0.23400	-1.61e-01	1.70e-01	1.08e-03	5.59e-04
Signaling by Nuclear Receptors	228	9.20e-05	6.61e-04	0.16600	-1.97e-02	1.65e-01	6.08e-01	1.77e-05
Interleukin-1 signaling	96	9.53e-05	6.82e-04	0.27500	-1.39e-01	2.37e-01	1.84e-02	5.88e-05
Gene expression (Transcription)	1171	1.05e-04	7.50e-04	0.08010	-3.35e-02	7.27e-02	5.62e-02	3.36e-05
CD22 mediated BCR regulation	20	1.18e-04	8.34e-04	0.57000	-1.57e-01	5.48e-01	2.25e-01	2.22e-05
Clathrin-mediated endocytosis	133	1.24e-04	8.72e-04	0.21700	-4.15e-02	2.13e-01	4.09e-01	2.22e-05
RUNX1 regulates transcription of genes involved in differentiation of HSCs	77	1.25e-04	8.77e-04	0.30800	-2.13e-01	2.22e-01	1.21e-03	7.73e-04
Regulation of TLR by endogenous ligand	15	1.37e-04	9.55e-04	0.60500	4.64e-02	6.03e-01	7.56e-01	5.23e-05
CD28 co-stimulation	33	1.38e-04	9.60e-04	0.46600	-3.02e-01	3.55e-01	2.67e-03	4.20e-04
Stabilization of p53	54	1.41e-04	9.71e-04	0.36400	-2.82e-01	2.30e-01	3.42e-04	3.44e-03
Signaling by Hippo	20	1.41e-04	9.72e-04	0.58400	-2.66e-01	5.20e-01	3.92e-02	5.71e-05
DNA Replication Pre-Initiation	83	1.50e-04	1.02e-03	0.28900	-1.52e-01	2.46e-01	1.64e-02	1.07e-04
HSF1 activation	24	1.54e-04	1.05e-03	0.54200	-4.21e-01	3.42e-01	3.56e-04	3.74e-03
Cellular response to heat stress	93	1.61e-04	1.09e-03	0.27100	-1.35e-01	2.35e-01	2.45e-02	8.91e-05
Citric acid cycle (TCA cycle)	22	1.63e-04	1.10e-03	0.46600	2.01e-01	4.20e-01	1.03e-01	6.42e-04
Autodegradation of Cdh1 by Cdh1:APC/C	62	1.64e-04	1.10e-03	0.33700	-2.47e-01	2.30e-01	7.69e-04	1.75e-03
Hedgehog 'on' state	83	1.69e-04	1.13e-03	0.29000	-2.33e-01	1.72e-01	2.44e-04	6.69e-03
GPVI-mediated activation cascade	32	1.70e-04	1.13e-03	0.46800	-3.17e-01	3.44e-01	1.89e-03	7.51e-04
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	31	1.71e-04	1.13e-03	0.45200	-1.40e-01	4.29e-01	1.77e-01	3.51e-05
Cohesin Loading onto Chromatin	10	1.73e-04	1.13e-03	0.83200	-5.00e-01	6.65e-01	6.14e-03	2.70e-04
MAPK1/MAPK3 signaling	255	1.73e-04	1.13e-03	0.16700	-1.06e-01	1.29e-01	3.66e-03	4.18e-04
Signaling by WNT	264	1.79e-04	1.17e-03	0.15700	-5.64e-02	1.47e-01	1.15e-01	4.30e-05
Translocation of SLC2A4 (GLUT4) to the plasma membrane	51	1.82e-04	1.18e-03	0.33700	-4.17e-02	3.35e-01	6.07e-01	3.56e-05
Metabolism of polyamines	58	1.99e-04	1.29e-03	0.34200	-2.82e-01	1.94e-01	2.05e-04	1.08e-02
UCH proteinases	87	2.13e-04	1.37e-03	0.28000	-2.20e-01	1.73e-01	4.01e-04	5.19e-03
RNA Polymerase II Pre-transcription Events	79	2.19e-04	1.40e-03	0.27900	-8.30e-02	2.66e-01	2.02e-01	4.44e-05
Intra-Golgi and retrograde Golgi-to-ER traffic	175	2.22e-04	1.42e-03	0.19500	-9.93e-02	1.68e-01	2.37e-02	1.32e-04
Cargo concentration in the ER	29	2.32e-04	1.47e-03	0.47400	-4.12e-01	2.34e-01	1.21e-04	2.89e-02
Interleukin-12 family signaling	46	2.55e-04	1.61e-03	0.36800	-1.46e-01	3.38e-01	8.70e-02	7.21e-05
FLT3 Signaling	264	2.62e-04	1.64e-03	0.16000	-1.07e-01	1.19e-01	2.82e-03	8.91e-04
RAF/MAP kinase cascade	250	2.77e-04	1.73e-03	0.16400	-1.05e-01	1.26e-01	4.47e-03	6.30e-04
RHO GTPases Activate WASPs and WAVEs	36	2.84e-04	1.77e-03	0.38700	-3.19e-02	3.86e-01	7.41e-01	6.16e-05
TNFR2 non-canonical NF-kB pathway	90	2.85e-04	1.77e-03	0.27100	-2.08e-01	1.74e-01	6.57e-04	4.45e-03
Signaling by NOTCH	179	2.91e-04	1.79e-03	0.19300	-1.32e-01	1.40e-01	2.36e-03	1.21e-03
Glycolysis	66	2.92e-04	1.79e-03	0.26000	2.34e-01	1.14e-01	1.02e-03	1.11e-01
Costimulation by the CD28 family	61	2.93e-04	1.79e-03	0.32800	-2.12e-01	2.51e-01	4.28e-03	7.03e-04
APC/C:Cdc20 mediated degradation of Securin	66	3.29e-04	2.01e-03	0.31400	-2.27e-01	2.17e-01	1.42e-03	2.35e-03
SCF(Skp2)-mediated degradation of p27/p21	58	3.38e-04	2.05e-03	0.33400	-2.30e-01	2.42e-01	2.45e-03	1.42e-03
Cyclin A:Cdk2-associated events at S phase entry	83	3.58e-04	2.16e-03	0.27400	-1.41e-01	2.35e-01	2.68e-02	2.11e-04
FCGR3A-mediated IL10 synthesis	52	3.70e-04	2.23e-03	0.33900	-1.33e-01	3.11e-01	9.77e-02	1.03e-04
Smooth Muscle Contraction	29	3.83e-04	2.30e-03	0.43100	-7.26e-02	4.25e-01	4.99e-01	7.40e-05
Amino acid transport across the plasma membrane	31	3.89e-04	2.32e-03	0.45300	3.10e-01	-3.30e-01	2.86e-03	1.46e-03
Ub-specific processing proteases	164	3.94e-04	2.33e-03	0.19700	-1.28e-01	1.50e-01	4.73e-03	9.32e-04
Late Phase of HIV Life Cycle	132	3.94e-04	2.33e-03	0.19800	-1.25e-02	1.97e-01	8.04e-01	9.07e-05
Translesion synthesis by POLK	17	4.04e-04	2.38e-03	0.49200	3.16e-01	3.77e-01	2.39e-02	7.12e-03
Regulation of HSF1-mediated heat shock response	77	4.07e-04	2.39e-03	0.27900	-1.20e-01	2.52e-01	6.92e-02	1.37e-04
Cristae formation	29	4.15e-04	2.42e-03	0.37600	2.56e-01	2.75e-01	1.71e-02	1.03e-02
Interleukin-12 signaling	37	4.36e-04	2.54e-03	0.39600	-1.53e-01	3.66e-01	1.06e-01	1.19e-04
mRNA Splicing - Major Pathway	172	4.41e-04	2.55e-03	0.19100	-1.16e-01	1.51e-01	8.81e-03	6.26e-04
rRNA processing in the mitochondrion	22	4.47e-04	2.58e-03	0.45600	8.29e-02	4.48e-01	5.01e-01	2.74e-04
G2/M Checkpoints	133	4.50e-04	2.59e-03	0.20900	-8.08e-02	1.93e-01	1.08e-01	1.23e-04
Switching of origins to a post-replicative state	88	4.52e-04	2.59e-03	0.26100	-1.28e-01	2.28e-01	3.87e-02	2.17e-04
Interleukin-4 and Interleukin-13 signaling	95	4.98e-04	2.84e-03	0.22600	4.07e-03	2.26e-01	9.45e-01	1.47e-04
CTLA4 inhibitory signaling	20	5.00e-04	2.84e-03	0.51100	-8.70e-02	5.03e-01	5.01e-01	9.78e-05
HSF1-dependent transactivation	31	5.15e-04	2.91e-03	0.43500	-3.84e-01	2.05e-01	2.19e-04	4.86e-02
Opioid Signalling	84	5.73e-04	3.22e-03	0.22300	8.36e-02	2.06e-01	1.86e-01	1.09e-03
Keratinization	39	5.80e-04	3.25e-03	0.38000	3.48e-01	-1.53e-01	1.71e-04	9.74e-02
Apoptotic cleavage of cellular proteins	35	5.92e-04	3.30e-03	0.34300	1.33e-01	3.16e-01	1.74e-01	1.21e-03
Toll Like Receptor 4 (TLR4) Cascade	117	5.94e-04	3.30e-03	0.21100	-4.11e-02	2.06e-01	4.43e-01	1.16e-04
Calnexin/calreticulin cycle	26	6.05e-04	3.35e-03	0.45900	-4.30e-01	1.61e-01	1.46e-04	1.57e-01
Metabolism of carbohydrates	264	6.33e-04	3.50e-03	0.12500	1.14e-01	5.02e-02	1.40e-03	1.61e-01
Semaphorin interactions	64	6.38e-04	3.51e-03	0.29100	-9.58e-02	2.75e-01	1.85e-01	1.45e-04
Translesion synthesis by REV1	16	6.41e-04	3.51e-03	0.49200	3.40e-01	3.55e-01	1.86e-02	1.39e-02
Glucuronidation	16	6.47e-04	3.53e-03	0.60900	4.48e-01	-4.13e-01	1.93e-03	4.27e-03
DNA Replication	123	6.83e-04	3.71e-03	0.20300	-3.73e-02	1.99e-01	4.75e-01	1.35e-04
Intrinsic Pathway for Apoptosis	48	7.29e-04	3.94e-03	0.30700	1.60e-02	3.06e-01	8.48e-01	2.43e-04
RHO GTPases activate PKNs	43	7.37e-04	3.97e-03	0.32200	2.62e-02	3.21e-01	7.66e-01	2.75e-04
Synthesis of DNA	116	7.91e-04	4.25e-03	0.20900	-5.10e-02	2.03e-01	3.44e-01	1.59e-04
Cell-extracellular matrix interactions	16	8.00e-04	4.28e-03	0.52600	3.13e-02	5.25e-01	8.29e-01	2.74e-04
Generic Transcription Pathway	932	8.57e-04	4.57e-03	0.07650	-2.36e-02	7.28e-02	2.27e-01	1.89e-04
Cdc20:Phospho-APC/C mediated degradation of Cyclin A	70	8.69e-04	4.61e-03	0.28600	-2.03e-01	2.02e-01	3.37e-03	3.57e-03
Apoptosis induced DNA fragmentation	13	8.97e-04	4.74e-03	0.53400	4.14e-01	3.37e-01	9.81e-03	3.54e-02
Extra-nuclear estrogen signaling	67	9.35e-04	4.93e-03	0.27000	-5.52e-02	2.64e-01	4.35e-01	1.88e-04
Syndecan interactions	19	9.74e-04	5.11e-03	0.44700	1.89e-01	4.05e-01	1.54e-01	2.22e-03
Mitotic Prometaphase	184	9.93e-04	5.20e-03	0.14400	6.29e-02	1.30e-01	1.42e-01	2.47e-03
Signaling by SCF-KIT	42	1.01e-03	5.24e-03	0.36400	-2.27e-01	2.84e-01	1.10e-02	1.44e-03
Signaling by TGFB family members	96	1.01e-03	5.25e-03	0.22400	-4.65e-02	2.19e-01	4.31e-01	2.04e-04
Degradation of DVL	56	1.09e-03	5.63e-03	0.31300	-2.50e-01	1.88e-01	1.24e-03	1.48e-02
Platelet calcium homeostasis	26	1.09e-03	5.63e-03	0.37300	3.03e-01	2.18e-01	7.54e-03	5.43e-02
PCP/CE pathway	89	1.13e-03	5.83e-03	0.24800	-1.90e-01	1.60e-01	1.94e-03	9.29e-03
Nucleotide Excision Repair	108	1.27e-03	6.51e-03	0.18800	5.64e-02	1.79e-01	3.12e-01	1.31e-03
CDK-mediated phosphorylation and removal of Cdc6	70	1.30e-03	6.63e-03	0.27800	-2.00e-01	1.92e-01	3.79e-03	5.45e-03
Recognition of DNA damage by PCNA-containing replication complex	29	1.32e-03	6.70e-03	0.35400	1.48e-01	3.22e-01	1.68e-01	2.68e-03
Transcription of the HIV genome	68	1.34e-03	6.79e-03	0.25900	-4.48e-02	2.55e-01	5.23e-01	2.78e-04
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint	71	1.37e-03	6.90e-03	0.27500	-1.96e-01	1.92e-01	4.37e-03	5.06e-03
Interleukin-1 family signaling	126	1.44e-03	7.24e-03	0.20200	-9.93e-02	1.76e-01	5.46e-02	6.68e-04
Complex I biogenesis	55	1.48e-03	7.42e-03	0.25100	1.99e-01	1.53e-01	1.08e-02	5.04e-02
Hedgehog 'off' state	98	1.50e-03	7.48e-03	0.22900	-1.96e-01	1.18e-01	8.11e-04	4.37e-02
Global Genome Nucleotide Excision Repair (GG-NER)	82	1.62e-03	8.07e-03	0.21700	3.40e-02	2.14e-01	5.95e-01	8.05e-04
Processing of Capped Intron-Containing Pre-mRNA	231	1.67e-03	8.27e-03	0.15000	-9.55e-02	1.16e-01	1.26e-02	2.42e-03
Beta-catenin independent WNT signaling	141	1.72e-03	8.48e-03	0.19100	-1.19e-01	1.50e-01	1.52e-02	2.14e-03
Asymmetric localization of PCP proteins	63	1.83e-03	8.99e-03	0.28500	-2.15e-01	1.87e-01	3.20e-03	1.05e-02
Cytosolic iron-sulfur cluster assembly	13	1.97e-03	9.67e-03	0.61700	5.07e-01	-3.53e-01	1.56e-03	2.77e-02
Translesion synthesis by POLI	17	2.01e-03	9.80e-03	0.43900	3.37e-01	2.81e-01	1.62e-02	4.47e-02
Mitochondrial translation	94	2.05e-03	9.97e-03	0.22500	-1.01e-01	2.02e-01	9.15e-02	7.38e-04
Transcriptional regulation by RUNX2	114	2.20e-03	1.07e-02	0.20400	-9.11e-02	1.82e-01	9.31e-02	7.91e-04
Dual Incision in GG-NER	40	2.25e-03	1.09e-02	0.28400	1.78e-01	2.21e-01	5.13e-02	1.56e-02
Nephrin family interactions	21	2.25e-03	1.09e-02	0.42800	8.36e-03	4.28e-01	9.47e-01	6.80e-04
mRNA Splicing	180	2.28e-03	1.10e-02	0.16600	-1.03e-01	1.30e-01	1.73e-02	2.74e-03
Mitochondrial translation initiation	88	2.33e-03	1.12e-02	0.22300	-6.38e-02	2.14e-01	3.02e-01	5.24e-04
Formation of the cornified envelope	26	2.57e-03	1.22e-02	0.42200	3.70e-01	-2.03e-01	1.10e-03	7.28e-02
Interleukin-3, Interleukin-5 and GM-CSF signaling	39	2.63e-03	1.25e-02	0.34900	-2.82e-01	2.05e-01	2.28e-03	2.68e-02
COPI-independent Golgi-to-ER retrograde traffic	33	2.69e-03	1.28e-02	0.36600	-1.34e-01	3.40e-01	1.84e-01	7.18e-04
Mitochondrial translation termination	88	2.76e-03	1.30e-02	0.22100	-6.83e-02	2.10e-01	2.69e-01	6.48e-04
Cellular hexose transport	16	2.77e-03	1.30e-02	0.53300	4.72e-01	-2.47e-01	1.08e-03	8.73e-02
RAF activation	33	2.79e-03	1.31e-02	0.34700	-4.74e-02	3.44e-01	6.37e-01	6.26e-04
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	72	2.89e-03	1.35e-02	0.25700	-1.71e-01	1.91e-01	1.19e-02	5.13e-03
Resolution of AP sites via the multiple-nucleotide patch replacement pathway	24	2.96e-03	1.38e-02	0.35800	2.80e-01	2.23e-01	1.75e-02	5.87e-02
ECM proteoglycans	47	3.01e-03	1.40e-02	0.25700	2.14e-01	1.42e-01	1.11e-02	9.30e-02
ATF6 (ATF6-alpha) activates chaperone genes	10	3.04e-03	1.41e-02	0.67700	-5.66e-01	3.72e-01	1.95e-03	4.16e-02
APC/C:Cdc20 mediated degradation of mitotic proteins	73	3.10e-03	1.43e-02	0.25300	-1.70e-01	1.88e-01	1.21e-02	5.56e-03
VEGFR2 mediated vascular permeability	27	3.19e-03	1.47e-02	0.39700	-1.38e-01	3.72e-01	2.16e-01	8.16e-04
Neddylation	224	3.22e-03	1.48e-02	0.14500	-1.08e-01	9.62e-02	5.36e-03	1.33e-02
Signaling by TGF-beta Receptor Complex	73	3.25e-03	1.48e-02	0.24800	-1.21e-01	2.16e-01	7.44e-02	1.42e-03
Formation of Incision Complex in GG-NER	42	3.29e-03	1.50e-02	0.30200	-3.24e-02	3.00e-01	7.17e-01	7.74e-04
Mitotic G2-G2/M phases	183	3.32e-03	1.51e-02	0.14800	-2.84e-02	1.45e-01	5.08e-01	7.30e-04
Activation of BAD and translocation to mitochondria	15	3.35e-03	1.52e-02	0.53600	-2.18e-01	4.90e-01	1.44e-01	1.03e-03
Interleukin-10 signaling	31	3.40e-03	1.53e-02	0.38500	-2.48e-01	2.94e-01	1.67e-02	4.68e-03
Pyruvate metabolism and Citric Acid (TCA) cycle	52	3.41e-03	1.53e-02	0.26400	1.41e-03	2.64e-01	9.86e-01	1.00e-03
trans-Golgi Network Vesicle Budding	70	3.42e-03	1.53e-02	0.25600	-1.74e-01	1.88e-01	1.19e-02	6.44e-03
Metabolism of nitric oxide: NOS3 activation and regulation	15	3.51e-03	1.57e-02	0.53000	-1.97e-01	4.92e-01	1.87e-01	9.60e-04
Mitochondrial translation elongation	88	3.58e-03	1.59e-02	0.21500	-6.11e-02	2.06e-01	3.22e-01	8.26e-04
G2/M Transition	181	3.65e-03	1.62e-02	0.14800	-2.93e-02	1.45e-01	4.97e-01	8.06e-04
Regulation of APC/C activators between G1/S and early anaphase	78	3.78e-03	1.67e-02	0.24100	-1.73e-01	1.68e-01	8.43e-03	1.03e-02
Cargo recognition for clathrin-mediated endocytosis	95	3.84e-03	1.69e-02	0.21000	-8.25e-02	1.94e-01	1.65e-01	1.12e-03
MyD88 deficiency (TLR2/4)	10	3.85e-03	1.69e-02	0.66900	-4.32e-01	5.11e-01	1.79e-02	5.18e-03
Formation of ATP by chemiosmotic coupling	16	3.96e-03	1.74e-02	0.43200	3.79e-01	2.08e-01	8.71e-03	1.49e-01
Glutamate and glutamine metabolism	13	3.99e-03	1.74e-02	0.48800	4.60e-01	1.65e-01	4.10e-03	3.03e-01
Diseases associated with N-glycosylation of proteins	16	4.00e-03	1.74e-02	0.42800	-3.51e-01	-2.46e-01	1.52e-02	8.89e-02
MyD88-independent TLR4 cascade	91	4.03e-03	1.74e-02	0.20400	-3.11e-02	2.01e-01	6.08e-01	9.15e-04
TRIF(TICAM1)-mediated TLR4 signaling	91	4.03e-03	1.74e-02	0.20400	-3.11e-02	2.01e-01	6.08e-01	9.15e-04
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins	74	4.03e-03	1.74e-02	0.24600	-1.67e-01	1.81e-01	1.31e-02	7.28e-03
Non-integrin membrane-ECM interactions	41	4.09e-03	1.76e-02	0.26700	1.63e-01	2.11e-01	7.03e-02	1.97e-02
CD28 dependent Vav1 pathway	12	4.16e-03	1.78e-02	0.60200	-3.38e-01	4.98e-01	4.27e-02	2.80e-03
PCNA-Dependent Long Patch Base Excision Repair	20	4.26e-03	1.82e-02	0.37900	2.93e-01	2.42e-01	2.35e-02	6.15e-02
IRAK4 deficiency (TLR2/4)	11	4.39e-03	1.87e-02	0.62800	-3.71e-01	5.06e-01	3.30e-02	3.65e-03
Role of phospholipids in phagocytosis	40	4.49e-03	1.91e-02	0.33000	-2.14e-01	2.52e-01	1.92e-02	5.92e-03
HCMV Late Events	63	4.56e-03	1.93e-02	0.21500	1.86e-01	1.08e-01	1.08e-02	1.38e-01
Activation of ATR in response to replication stress	37	4.64e-03	1.95e-02	0.27800	2.22e-01	1.66e-01	1.93e-02	8.08e-02
Pausing and recovery of Tat-mediated HIV elongation	30	4.67e-03	1.95e-02	0.30700	2.00e-01	2.33e-01	5.81e-02	2.72e-02
Tat-mediated HIV elongation arrest and recovery	30	4.67e-03	1.95e-02	0.30700	2.00e-01	2.33e-01	5.81e-02	2.72e-02
AMER1 mutants destabilize the destruction complex	14	4.72e-03	1.95e-02	0.46200	1.68e-01	4.30e-01	2.78e-01	5.32e-03
APC truncation mutants have impaired AXIN binding	14	4.72e-03	1.95e-02	0.46200	1.68e-01	4.30e-01	2.78e-01	5.32e-03
AXIN missense mutants destabilize the destruction complex	14	4.72e-03	1.95e-02	0.46200	1.68e-01	4.30e-01	2.78e-01	5.32e-03
AXIN mutants destabilize the destruction complex, activating WNT signaling	14	4.72e-03	1.95e-02	0.46200	1.68e-01	4.30e-01	2.78e-01	5.32e-03
Truncations of AMER1 destabilize the destruction complex	14	4.72e-03	1.95e-02	0.46200	1.68e-01	4.30e-01	2.78e-01	5.32e-03
truncated APC mutants destabilize the destruction complex	14	4.72e-03	1.95e-02	0.46200	1.68e-01	4.30e-01	2.78e-01	5.32e-03
Golgi Associated Vesicle Biogenesis	54	4.82e-03	1.98e-02	0.28200	-1.73e-01	2.22e-01	2.79e-02	4.71e-03
COPI-mediated anterograde transport	77	4.84e-03	1.98e-02	0.23000	-9.55e-02	2.09e-01	1.48e-01	1.54e-03
Circadian Clock	67	4.88e-03	2.00e-02	0.23700	-5.48e-02	2.31e-01	4.38e-01	1.11e-03
Sema3A PAK dependent Axon repulsion	16	5.00e-03	2.04e-02	0.51100	-2.76e-01	4.30e-01	5.60e-02	2.88e-03
Resolution of Abasic Sites (AP sites)	37	5.09e-03	2.07e-02	0.30200	3.02e-01	3.33e-04	1.50e-03	9.97e-01
Negative regulation of the PI3K/AKT network	94	5.20e-03	2.11e-02	0.20000	-4.89e-02	1.94e-01	4.13e-01	1.19e-03
Antigen processing: Ubiquitination & Proteasome degradation	288	5.23e-03	2.11e-02	0.12300	-8.45e-02	8.87e-02	1.38e-02	9.79e-03
DARPP-32 events	23	5.26e-03	2.12e-02	0.35100	1.71e-01	3.06e-01	1.55e-01	1.10e-02
TCF dependent signaling in response to WNT	172	5.38e-03	2.16e-02	0.15300	-6.34e-02	1.39e-01	1.52e-01	1.71e-03
Signaling by NTRK1 (TRKA)	106	5.44e-03	2.18e-02	0.18000	-9.88e-03	1.79e-01	8.61e-01	1.43e-03
Regulation of Complement cascade	52	5.48e-03	2.19e-02	0.26900	-7.84e-02	2.58e-01	3.28e-01	1.31e-03
ATF6 (ATF6-alpha) activates chaperones	12	5.54e-03	2.20e-02	0.58300	-4.97e-01	3.04e-01	2.85e-03	6.79e-02
Muscle contraction	144	5.60e-03	2.22e-02	0.14000	6.60e-02	1.24e-01	1.72e-01	1.04e-02
Transcription-Coupled Nucleotide Excision Repair (TC-NER)	77	5.90e-03	2.34e-02	0.19200	7.93e-02	1.75e-01	2.29e-01	8.12e-03
Dual incision in TC-NER	64	5.98e-03	2.36e-02	0.20800	1.04e-01	1.80e-01	1.49e-01	1.30e-02
HIV elongation arrest and recovery	32	6.11e-03	2.39e-02	0.29000	1.81e-01	2.27e-01	7.71e-02	2.62e-02
Pausing and recovery of HIV elongation	32	6.11e-03	2.39e-02	0.29000	1.81e-01	2.27e-01	7.71e-02	2.62e-02
Formation of RNA Pol II elongation complex	57	6.12e-03	2.39e-02	0.24600	-3.17e-02	2.44e-01	6.79e-01	1.47e-03
RNA Polymerase II Transcription Elongation	57	6.12e-03	2.39e-02	0.24600	-3.17e-02	2.44e-01	6.79e-01	1.47e-03
Platelet sensitization by LDL	17	6.21e-03	2.42e-02	0.40800	1.46e-01	3.81e-01	2.97e-01	6.47e-03
DNA strand elongation	31	6.32e-03	2.45e-02	0.29800	2.66e-01	1.35e-01	1.04e-02	1.92e-01
Formation of Fibrin Clot (Clotting Cascade)	28	6.34e-03	2.46e-02	0.31700	1.21e-01	2.93e-01	2.69e-01	7.35e-03
G-protein beta:gamma signalling	30	6.44e-03	2.49e-02	0.35600	-1.40e-01	3.27e-01	1.85e-01	1.92e-03
Base Excision Repair	51	6.55e-03	2.52e-02	0.25500	2.55e-01	-2.10e-02	1.67e-03	7.96e-01
Cellular Senescence	136	6.70e-03	2.57e-02	0.14700	1.43e-01	3.28e-02	3.92e-03	5.10e-01
Oncogenic MAPK signaling	77	6.97e-03	2.67e-02	0.21200	-4.28e-02	2.08e-01	5.17e-01	1.62e-03
Acetylcholine binding and downstream events	11	7.08e-03	2.70e-02	0.49900	-1.96e-01	-4.59e-01	2.62e-01	8.43e-03
Postsynaptic nicotinic acetylcholine receptors	11	7.08e-03	2.70e-02	0.49900	-1.96e-01	-4.59e-01	2.62e-01	8.43e-03
Response of EIF2AK1 (HRI) to heme deficiency	15	7.13e-03	2.71e-02	0.50300	-2.28e-01	4.49e-01	1.26e-01	2.62e-03
Common Pathway of Fibrin Clot Formation	16	7.47e-03	2.83e-02	0.42400	8.61e-02	4.15e-01	5.51e-01	4.03e-03
p53-Dependent G1 DNA Damage Response	62	7.81e-03	2.94e-02	0.25200	-1.74e-01	1.82e-01	1.78e-02	1.32e-02
p53-Dependent G1/S DNA damage checkpoint	62	7.81e-03	2.94e-02	0.25200	-1.74e-01	1.82e-01	1.78e-02	1.32e-02
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)	12	7.93e-03	2.98e-02	0.52800	5.18e-01	-9.83e-02	1.87e-03	5.56e-01
MyD88:MAL(TIRAP) cascade initiated on plasma membrane	89	8.21e-03	3.05e-02	0.18700	-4.18e-03	1.87e-01	9.46e-01	2.35e-03
Toll Like Receptor 2 (TLR2) Cascade	89	8.21e-03	3.05e-02	0.18700	-4.18e-03	1.87e-01	9.46e-01	2.35e-03
Toll Like Receptor TLR1:TLR2 Cascade	89	8.21e-03	3.05e-02	0.18700	-4.18e-03	1.87e-01	9.46e-01	2.35e-03
Toll Like Receptor TLR6:TLR2 Cascade	89	8.21e-03	3.05e-02	0.18700	-4.18e-03	1.87e-01	9.46e-01	2.35e-03
Infection with Mycobacterium tuberculosis	26	8.34e-03	3.09e-02	0.37500	-1.65e-01	3.37e-01	1.46e-01	2.91e-03
Toll Like Receptor 3 (TLR3) Cascade	88	8.35e-03	3.09e-02	0.19000	-1.55e-02	1.89e-01	8.02e-01	2.17e-03
Activation of BH3-only proteins	29	8.37e-03	3.09e-02	0.33500	-4.95e-02	3.31e-01	6.44e-01	2.02e-03
CD28 dependent PI3K/Akt signaling	22	8.60e-03	3.15e-02	0.41800	-2.98e-01	2.94e-01	1.56e-02	1.71e-02
Resolution of Sister Chromatid Cohesion	103	8.60e-03	3.15e-02	0.17100	5.94e-03	1.71e-01	9.17e-01	2.79e-03
HCMV Infection	90	8.78e-03	3.18e-02	0.16800	9.06e-02	1.42e-01	1.38e-01	2.04e-02
CDC6 association with the ORC:origin complex	11	8.79e-03	3.18e-02	0.50100	1.09e-01	4.89e-01	5.30e-01	4.94e-03
RHO GTPases activate IQGAPs	11	8.83e-03	3.18e-02	0.53500	-5.58e-02	5.32e-01	7.49e-01	2.23e-03
Misspliced GSK3beta mutants stabilize beta-catenin	15	8.87e-03	3.18e-02	0.42800	1.01e-01	4.16e-01	4.98e-01	5.33e-03
S33 mutants of beta-catenin aren't phosphorylated	15	8.87e-03	3.18e-02	0.42800	1.01e-01	4.16e-01	4.98e-01	5.33e-03
S37 mutants of beta-catenin aren't phosphorylated	15	8.87e-03	3.18e-02	0.42800	1.01e-01	4.16e-01	4.98e-01	5.33e-03
S45 mutants of beta-catenin aren't phosphorylated	15	8.87e-03	3.18e-02	0.42800	1.01e-01	4.16e-01	4.98e-01	5.33e-03
T41 mutants of beta-catenin aren't phosphorylated	15	8.87e-03	3.18e-02	0.42800	1.01e-01	4.16e-01	4.98e-01	5.33e-03
phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex	15	8.87e-03	3.18e-02	0.42800	1.01e-01	4.16e-01	4.98e-01	5.33e-03
Fatty acid metabolism	150	9.37e-03	3.35e-02	0.13900	1.07e-02	1.39e-01	8.21e-01	3.38e-03
Endogenous sterols	19	9.64e-03	3.43e-02	0.36900	1.36e-01	3.43e-01	3.05e-01	9.70e-03
Signaling by ERBB2	48	9.64e-03	3.43e-02	0.28000	-2.04e-01	1.91e-01	1.43e-02	2.20e-02
Signalling to ERKs	32	9.69e-03	3.44e-02	0.33800	-1.78e-01	2.87e-01	8.13e-02	4.96e-03
Elevation of cytosolic Ca2+ levels	15	9.91e-03	3.51e-02	0.41400	3.87e-01	1.49e-01	9.51e-03	3.19e-01
Disassembly of the destruction complex and recruitment of AXIN to the membrane	28	9.98e-03	3.52e-02	0.29800	2.56e-01	1.51e-01	1.89e-02	1.66e-01
COPII-mediated vesicle transport	63	1.05e-02	3.68e-02	0.24200	-1.65e-01	1.77e-01	2.35e-02	1.51e-02
RAB geranylgeranylation	59	1.05e-02	3.68e-02	0.22000	1.22e-02	2.19e-01	8.71e-01	3.59e-03
G1/S DNA Damage Checkpoints	64	1.07e-02	3.75e-02	0.24000	-1.70e-01	1.69e-01	1.84e-02	1.96e-02
RHO GTPases Activate ROCKs	19	1.13e-02	3.94e-02	0.37900	4.52e-02	3.76e-01	7.33e-01	4.57e-03
APC/C-mediated degradation of cell cycle proteins	85	1.16e-02	4.03e-02	0.20500	-1.22e-01	1.65e-01	5.12e-02	8.72e-03
Regulation of mitotic cell cycle	85	1.16e-02	4.03e-02	0.20500	-1.22e-01	1.65e-01	5.12e-02	8.72e-03
Na+/Cl- dependent neurotransmitter transporters	15	1.16e-02	4.03e-02	0.44000	2.23e-02	-4.39e-01	8.81e-01	3.23e-03
Telomere Maintenance	71	1.16e-02	4.03e-02	0.20300	2.03e-01	-1.21e-02	3.19e-03	8.60e-01
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	87	1.19e-02	4.10e-02	0.18800	-3.57e-02	1.85e-01	5.65e-01	2.91e-03
O-glycosylation of TSR domain-containing proteins	37	1.20e-02	4.13e-02	0.25100	1.73e-01	1.82e-01	6.87e-02	5.58e-02
Pyrimidine salvage	10	1.25e-02	4.29e-02	0.57000	5.33e-01	-2.00e-01	3.49e-03	2.74e-01
Mitotic Telophase/Cytokinesis	13	1.25e-02	4.29e-02	0.51700	-2.93e-01	4.27e-01	6.76e-02	7.75e-03
Unfolded Protein Response (UPR)	89	1.26e-02	4.32e-02	0.19700	-1.66e-01	1.06e-01	6.73e-03	8.34e-02
eNOS activation	11	1.27e-02	4.32e-02	0.54000	-1.76e-01	5.10e-01	3.13e-01	3.39e-03
DNA Damage/Telomere Stress Induced Senescence	39	1.27e-02	4.33e-02	0.26300	2.62e-01	2.22e-02	4.71e-03	8.10e-01
Centrosome maturation	81	1.28e-02	4.33e-02	0.16900	1.15e-01	1.24e-01	7.43e-02	5.48e-02
Recruitment of mitotic centrosome proteins and complexes	81	1.28e-02	4.33e-02	0.16900	1.15e-01	1.24e-01	7.43e-02	5.48e-02
Toll Like Receptor 7/8 (TLR7/8) Cascade	85	1.28e-02	4.34e-02	0.18100	3.52e-04	1.81e-01	9.96e-01	3.94e-03
DNA Damage Bypass	46	1.31e-02	4.42e-02	0.22900	8.26e-02	2.14e-01	3.33e-01	1.20e-02
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	39	1.33e-02	4.48e-02	0.29700	-1.69e-01	2.44e-01	6.77e-02	8.36e-03
Regulation of signaling by CBL	18	1.35e-02	4.53e-02	0.43600	-2.52e-01	3.57e-01	6.46e-02	8.81e-03
RAB GEFs exchange GTP for GDP on RABs	86	1.36e-02	4.55e-02	0.19200	-6.61e-02	1.81e-01	2.90e-01	3.78e-03
Pentose phosphate pathway	14	1.37e-02	4.59e-02	0.40400	2.27e-01	3.34e-01	1.42e-01	3.04e-02
Metabolism of amino acids and derivatives	308	1.42e-02	4.73e-02	0.08780	3.75e-02	7.94e-02	2.59e-01	1.69e-02
Toll Like Receptor 9 (TLR9) Cascade	88	1.43e-02	4.73e-02	0.17800	-9.50e-03	1.78e-01	8.78e-01	4.01e-03
TP53 Regulates Transcription of Cell Cycle Genes	46	1.43e-02	4.73e-02	0.22400	1.99e-01	1.04e-01	1.98e-02	2.23e-01
Endosomal Sorting Complex Required For Transport (ESCRT)	30	1.46e-02	4.84e-02	0.30500	-2.70e-02	3.04e-01	7.98e-01	3.93e-03
Chemokine receptors bind chemokines	39	1.48e-02	4.88e-02	0.29300	-2.42e-01	1.66e-01	8.97e-03	7.35e-02
Defective B3GALTL causes Peters-plus syndrome (PpS)	36	1.49e-02	4.90e-02	0.24800	1.69e-01	1.81e-01	7.87e-02	5.98e-02
Ion transport by P-type ATPases	46	1.55e-02	5.08e-02	0.24300	-9.99e-03	2.42e-01	9.07e-01	4.45e-03
Regulation of KIT signaling	16	1.57e-02	5.14e-02	0.45800	-3.20e-01	3.28e-01	2.65e-02	2.32e-02
Downregulation of SMAD2/3:SMAD4 transcriptional activity	23	1.60e-02	5.22e-02	0.38000	-2.97e-01	2.38e-01	1.38e-02	4.82e-02
FOXO-mediated transcription	61	1.62e-02	5.27e-02	0.19700	5.65e-02	1.88e-01	4.46e-01	1.09e-02
Diseases associated with O-glycosylation of proteins	58	1.64e-02	5.35e-02	0.19700	1.80e-01	8.22e-02	1.81e-02	2.79e-01
RHO GTPases activate PAKs	21	1.65e-02	5.35e-02	0.37100	-8.60e-02	3.61e-01	4.95e-01	4.18e-03
Signaling by RAF1 mutants	38	1.65e-02	5.35e-02	0.27500	-5.65e-02	2.69e-01	5.47e-01	4.17e-03
Josephin domain DUBs	11	1.66e-02	5.35e-02	0.51900	-4.96e-01	1.52e-01	4.38e-03	3.84e-01
G-protein mediated events	51	1.67e-02	5.35e-02	0.21500	6.03e-02	2.06e-01	4.57e-01	1.10e-02
Golgi-to-ER retrograde transport	112	1.67e-02	5.35e-02	0.17200	-1.13e-01	1.30e-01	3.90e-02	1.76e-02
Senescence-Associated Secretory Phenotype (SASP)	55	1.67e-02	5.35e-02	0.20600	1.97e-01	5.98e-02	1.14e-02	4.43e-01
PLC beta mediated events	50	1.72e-02	5.51e-02	0.21500	6.49e-02	2.05e-01	4.28e-01	1.22e-02
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	83	1.73e-02	5.54e-02	0.17500	8.35e-03	1.75e-01	8.95e-01	5.92e-03
Regulation of TP53 Activity	152	1.76e-02	5.61e-02	0.12500	2.83e-02	1.22e-01	5.47e-01	9.68e-03
NOTCH4 Intracellular Domain Regulates Transcription	18	1.77e-02	5.62e-02	0.35600	1.11e-01	3.38e-01	4.15e-01	1.29e-02
Cell-Cell communication	108	1.77e-02	5.62e-02	0.15400	2.95e-03	1.54e-01	9.58e-01	5.72e-03
Ion homeostasis	43	1.79e-02	5.65e-02	0.23100	7.00e-02	2.20e-01	4.27e-01	1.26e-02
Signaling by PDGF	50	1.81e-02	5.72e-02	0.23800	-5.72e-02	2.31e-01	4.84e-01	4.65e-03
MyD88 dependent cascade initiated on endosome	84	1.84e-02	5.79e-02	0.17400	6.27e-04	1.74e-01	9.92e-01	5.77e-03
Activation of the pre-replicative complex	32	1.88e-02	5.92e-02	0.25600	1.62e-01	1.98e-01	1.12e-01	5.26e-02
Unwinding of DNA	12	1.90e-02	5.93e-02	0.41700	2.66e-01	3.21e-01	1.10e-01	5.39e-02
FOXO-mediated transcription of cell cycle genes	15	1.90e-02	5.93e-02	0.38400	3.58e-01	1.39e-01	1.65e-02	3.51e-01
Beta-catenin phosphorylation cascade	17	1.90e-02	5.93e-02	0.35900	1.42e-01	3.29e-01	3.10e-01	1.87e-02
Translesion Synthesis by POLH	18	1.91e-02	5.95e-02	0.36000	7.20e-02	3.52e-01	5.97e-01	9.64e-03
Caspase-mediated cleavage of cytoskeletal proteins	12	1.92e-02	5.98e-02	0.42500	1.77e-01	3.87e-01	2.89e-01	2.04e-02
Scavenging by Class A Receptors	16	1.95e-02	6.04e-02	0.38600	4.68e-02	3.84e-01	7.46e-01	7.91e-03
Other semaphorin interactions	19	1.97e-02	6.08e-02	0.40400	-2.19e-01	3.40e-01	9.88e-02	1.03e-02
rRNA modification in the nucleus and cytosol	55	1.99e-02	6.15e-02	0.23000	-8.10e-02	2.15e-01	2.99e-01	5.78e-03
Recruitment of NuMA to mitotic centrosomes	80	2.01e-02	6.20e-02	0.16100	1.26e-01	1.00e-01	5.17e-02	1.22e-01
Synthesis of very long-chain fatty acyl-CoAs	19	2.05e-02	6.29e-02	0.35800	1.32e-02	3.58e-01	9.20e-01	6.88e-03
MyD88 cascade initiated on plasma membrane	77	2.08e-02	6.36e-02	0.17200	3.72e-02	1.68e-01	5.73e-01	1.10e-02
Toll Like Receptor 10 (TLR10) Cascade	77	2.08e-02	6.36e-02	0.17200	3.72e-02	1.68e-01	5.73e-01	1.10e-02
Toll Like Receptor 5 (TLR5) Cascade	77	2.08e-02	6.36e-02	0.17200	3.72e-02	1.68e-01	5.73e-01	1.10e-02
Transcriptional regulation by RUNX1	174	2.09e-02	6.38e-02	0.13500	-9.35e-02	9.70e-02	3.36e-02	2.76e-02
Initial triggering of complement	33	2.10e-02	6.38e-02	0.29100	-8.30e-02	2.79e-01	4.09e-01	5.63e-03
Gap-filling DNA repair synthesis and ligation in TC-NER	63	2.10e-02	6.38e-02	0.18200	9.25e-02	1.56e-01	2.04e-01	3.18e-02
Response of Mtb to phagocytosis	22	2.13e-02	6.45e-02	0.37200	-2.02e-01	3.12e-01	1.02e-01	1.12e-02
RORA activates gene expression	18	2.14e-02	6.46e-02	0.41600	-2.99e-01	2.89e-01	2.81e-02	3.40e-02
MAP kinase activation	60	2.14e-02	6.46e-02	0.20300	-1.69e-03	2.03e-01	9.82e-01	6.65e-03
BBSome-mediated cargo-targeting to cilium	21	2.18e-02	6.55e-02	0.36400	-3.46e-01	1.13e-01	5.99e-03	3.71e-01
RHO GTPases Activate Formins	117	2.20e-02	6.61e-02	0.14500	-2.90e-03	1.45e-01	9.57e-01	6.71e-03
Tie2 Signaling	18	2.21e-02	6.63e-02	0.40100	-1.68e-01	3.64e-01	2.18e-01	7.46e-03
Signaling by EGFR	46	2.27e-02	6.79e-02	0.25300	-2.21e-01	1.24e-01	9.56e-03	1.46e-01
Synaptic adhesion-like molecules	21	2.28e-02	6.80e-02	0.38100	2.92e-01	-2.44e-01	2.04e-02	5.29e-02
Chromosome Maintenance	95	2.28e-02	6.80e-02	0.16000	1.60e-01	-2.78e-03	7.01e-03	9.63e-01
Synthesis of PIPs at the plasma membrane	52	2.31e-02	6.85e-02	0.22400	-4.33e-02	2.20e-01	5.90e-01	6.05e-03
EML4 and NUDC in mitotic spindle formation	94	2.35e-02	6.98e-02	0.15400	3.01e-02	1.51e-01	6.14e-01	1.16e-02
Complement cascade	59	2.43e-02	7.19e-02	0.21000	-4.46e-02	2.05e-01	5.53e-01	6.40e-03
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)	12	2.44e-02	7.21e-02	0.46200	4.54e-01	-8.54e-02	6.45e-03	6.09e-01
Downregulation of TGF-beta receptor signaling	26	2.45e-02	7.22e-02	0.32600	-1.17e-01	3.04e-01	3.01e-01	7.33e-03
AURKA Activation by TPX2	72	2.47e-02	7.27e-02	0.16500	1.03e-01	1.29e-01	1.31e-01	5.86e-02
Paradoxical activation of RAF signaling by kinase inactive BRAF	41	2.54e-02	7.41e-02	0.25400	-6.84e-02	2.44e-01	4.49e-01	6.86e-03
Signaling by RAS mutants	41	2.54e-02	7.41e-02	0.25400	-6.84e-02	2.44e-01	4.49e-01	6.86e-03
Signaling by moderate kinase activity BRAF mutants	41	2.54e-02	7.41e-02	0.25400	-6.84e-02	2.44e-01	4.49e-01	6.86e-03
Signaling downstream of RAS mutants	41	2.54e-02	7.41e-02	0.25400	-6.84e-02	2.44e-01	4.49e-01	6.86e-03
Base-Excision Repair, AP Site Formation	24	2.73e-02	7.93e-02	0.34700	2.73e-01	-2.14e-01	2.05e-02	6.94e-02
Signaling by NTRKs	125	2.79e-02	8.09e-02	0.13400	8.54e-03	1.33e-01	8.69e-01	1.00e-02
Regulation of PLK1 Activity at G2/M Transition	87	2.79e-02	8.09e-02	0.15300	5.02e-02	1.44e-01	4.19e-01	2.03e-02
ABC-family proteins mediated transport	97	2.84e-02	8.21e-02	0.17200	-1.34e-01	1.08e-01	2.23e-02	6.70e-02
EPH-ephrin mediated repulsion of cells	47	2.86e-02	8.24e-02	0.21300	3.11e-02	2.11e-01	7.12e-01	1.23e-02
Mismatch Repair	13	2.88e-02	8.28e-02	0.44200	4.26e-01	-1.17e-01	7.84e-03	4.67e-01
TP53 Regulates Metabolic Genes	84	2.88e-02	8.28e-02	0.15500	4.70e-02	1.48e-01	4.57e-01	1.92e-02
G beta:gamma signalling through PI3Kgamma	23	2.92e-02	8.37e-02	0.33500	-1.07e-01	3.18e-01	3.75e-01	8.36e-03
Activation of RAC1	12	2.92e-02	8.37e-02	0.47900	-2.39e-01	4.15e-01	1.51e-01	1.28e-02
Mitotic Prophase	89	2.95e-02	8.38e-02	0.14500	8.73e-02	1.16e-01	1.55e-01	5.90e-02
Formation of HIV-1 elongation complex containing HIV-1 Tat	42	2.95e-02	8.38e-02	0.21800	6.94e-02	2.07e-01	4.37e-01	2.06e-02
HIV Transcription Elongation	42	2.95e-02	8.38e-02	0.21800	6.94e-02	2.07e-01	4.37e-01	2.06e-02
Tat-mediated elongation of the HIV-1 transcript	42	2.95e-02	8.38e-02	0.21800	6.94e-02	2.07e-01	4.37e-01	2.06e-02
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects	17	2.97e-02	8.38e-02	0.33100	2.70e-01	1.92e-01	5.38e-02	1.70e-01
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)	17	2.97e-02	8.38e-02	0.33100	2.70e-01	1.92e-01	5.38e-02	1.70e-01
Prolonged ERK activation events	14	2.97e-02	8.38e-02	0.44900	-2.75e-01	3.55e-01	7.53e-02	2.15e-02
MAPK targets/ Nuclear events mediated by MAP kinases	30	2.98e-02	8.38e-02	0.29200	-8.77e-02	2.78e-01	4.06e-01	8.38e-03
TGF-beta receptor signaling activates SMADs	32	2.98e-02	8.38e-02	0.28900	-1.21e-01	2.62e-01	2.36e-01	1.02e-02
Cytosolic tRNA aminoacylation	24	3.00e-02	8.41e-02	0.34000	-1.82e-01	2.87e-01	1.23e-01	1.50e-02
Mitotic Spindle Checkpoint	106	3.00e-02	8.41e-02	0.13800	3.78e-02	1.33e-01	5.02e-01	1.83e-02
Metalloprotease DUBs	20	3.04e-02	8.50e-02	0.36900	-1.82e-01	3.21e-01	1.60e-01	1.30e-02
Iron uptake and transport	56	3.09e-02	8.61e-02	0.21700	-8.73e-02	1.99e-01	2.59e-01	1.02e-02
Interaction between L1 and Ankyrins	25	3.09e-02	8.61e-02	0.29900	2.99e-01	-4.88e-03	9.73e-03	9.66e-01
Formation of HIV elongation complex in the absence of HIV Tat	44	3.10e-02	8.61e-02	0.21200	6.12e-02	2.03e-01	4.83e-01	1.96e-02
Miscellaneous substrates	10	3.11e-02	8.63e-02	0.47000	4.70e-01	-1.28e-05	1.00e-02	1.00e+00
Voltage gated Potassium channels	35	3.12e-02	8.64e-02	0.25300	9.22e-03	-2.53e-01	9.25e-01	9.56e-03
HIV Transcription Initiation	46	3.19e-02	8.70e-02	0.22900	-4.61e-02	2.24e-01	5.89e-01	8.65e-03
RNA Polymerase II HIV Promoter Escape	46	3.19e-02	8.70e-02	0.22900	-4.61e-02	2.24e-01	5.89e-01	8.65e-03
RNA Polymerase II Promoter Escape	46	3.19e-02	8.70e-02	0.22900	-4.61e-02	2.24e-01	5.89e-01	8.65e-03
RNA Polymerase II Transcription Initiation	46	3.19e-02	8.70e-02	0.22900	-4.61e-02	2.24e-01	5.89e-01	8.65e-03
RNA Polymerase II Transcription Initiation And Promoter Clearance	46	3.19e-02	8.70e-02	0.22900	-4.61e-02	2.24e-01	5.89e-01	8.65e-03
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening	46	3.19e-02	8.70e-02	0.22900	-4.61e-02	2.24e-01	5.89e-01	8.65e-03
Neuronal System	328	3.20e-02	8.73e-02	0.09290	5.96e-02	-7.12e-02	6.42e-02	2.71e-02
Chaperonin-mediated protein folding	87	3.26e-02	8.85e-02	0.17100	-6.16e-02	1.60e-01	3.21e-01	1.00e-02
Loss of Nlp from mitotic centrosomes	69	3.27e-02	8.85e-02	0.16200	9.70e-02	1.30e-01	1.64e-01	6.17e-02
Loss of proteins required for interphase microtubule organization from the centrosome	69	3.27e-02	8.85e-02	0.16200	9.70e-02	1.30e-01	1.64e-01	6.17e-02
Laminin interactions	23	3.31e-02	8.95e-02	0.28100	2.29e-01	1.62e-01	5.75e-02	1.78e-01
E2F mediated regulation of DNA replication	22	3.32e-02	8.97e-02	0.28600	1.74e-01	2.27e-01	1.58e-01	6.51e-02
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	38	3.38e-02	9.11e-02	0.21700	1.59e-01	1.47e-01	9.01e-02	1.16e-01
Interleukin-2 family signaling	36	3.42e-02	9.21e-02	0.24900	-2.48e-01	2.24e-02	9.93e-03	8.16e-01
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	16	3.49e-02	9.38e-02	0.33200	2.45e-01	2.25e-01	9.04e-02	1.20e-01
Frs2-mediated activation	12	3.51e-02	9.42e-02	0.46400	-2.13e-01	4.12e-01	2.02e-01	1.35e-02
BMAL1:CLOCK,NPAS2 activates circadian gene expression	26	3.52e-02	9.42e-02	0.31400	-1.38e-01	2.82e-01	2.23e-01	1.28e-02
CLEC7A (Dectin-1) induces NFAT activation	11	3.55e-02	9.47e-02	0.42400	7.91e-02	4.16e-01	6.50e-01	1.69e-02
ER Quality Control Compartment (ERQC)	21	3.56e-02	9.50e-02	0.34400	-3.20e-01	1.25e-01	1.11e-02	3.21e-01
Formation of Senescence-Associated Heterochromatin Foci (SAHF)	16	3.69e-02	9.80e-02	0.35700	3.56e-01	2.65e-02	1.37e-02	8.54e-01
RUNX3 regulates NOTCH signaling	14	3.70e-02	9.83e-02	0.36500	1.12e-01	3.48e-01	4.70e-01	2.42e-02
Recycling pathway of L1	27	3.74e-02	9.91e-02	0.29200	-6.44e-02	2.85e-01	5.62e-01	1.04e-02
L1CAM interactions	92	3.80e-02	1.00e-01	0.14000	5.67e-02	1.28e-01	3.48e-01	3.35e-02
Vasopressin regulates renal water homeostasis via Aquaporins	39	3.87e-02	1.02e-01	0.21000	1.31e-01	1.64e-01	1.56e-01	7.68e-02
Receptor-type tyrosine-protein phosphatases	17	3.98e-02	1.05e-01	0.38900	3.16e-01	-2.26e-01	2.40e-02	1.06e-01
DAP12 signaling	29	4.02e-02	1.06e-01	0.29900	-1.90e-01	2.31e-01	7.69e-02	3.15e-02
Signaling by BRAF and RAF fusions	60	4.04e-02	1.06e-01	0.19500	-4.92e-02	1.89e-01	5.10e-01	1.14e-02
MET activates RAP1 and RAC1	11	4.07e-02	1.07e-01	0.48300	-3.00e-01	3.79e-01	8.53e-02	2.94e-02
Signaling by WNT in cancer	33	4.14e-02	1.08e-01	0.22600	1.68e-01	1.50e-01	9.47e-02	1.35e-01
Protein-protein interactions at synapses	80	4.15e-02	1.08e-01	0.18000	1.20e-01	-1.34e-01	6.37e-02	3.89e-02
Mitochondrial biogenesis	89	4.18e-02	1.09e-01	0.13900	7.35e-02	1.17e-01	2.31e-01	5.57e-02
Nuclear Envelope (NE) Reassembly	67	4.20e-02	1.09e-01	0.16900	2.35e-02	1.67e-01	7.40e-01	1.78e-02
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal	90	4.24e-02	1.10e-01	0.14300	3.28e-02	1.40e-01	5.91e-01	2.23e-02
Amplification of signal from the kinetochores	90	4.24e-02	1.10e-01	0.14300	3.28e-02	1.40e-01	5.91e-01	2.23e-02
Incretin synthesis, secretion, and inactivation	12	4.25e-02	1.10e-01	0.43600	-4.17e-01	1.28e-01	1.24e-02	4.42e-01
Gap-filling DNA repair synthesis and ligation in GG-NER	24	4.36e-02	1.13e-01	0.26200	1.73e-01	1.97e-01	1.41e-01	9.54e-02
Viral Messenger RNA Synthesis	44	4.38e-02	1.13e-01	0.20000	1.87e-01	6.97e-02	3.19e-02	4.24e-01
Intra-Golgi traffic	41	4.41e-02	1.13e-01	0.22300	-1.00e-02	2.22e-01	9.12e-01	1.38e-02
Serotonin Neurotransmitter Release Cycle	15	4.41e-02	1.13e-01	0.38900	1.20e-01	-3.70e-01	4.20e-01	1.31e-02
Negative regulation of MET activity	20	4.43e-02	1.14e-01	0.35500	-2.42e-01	2.59e-01	6.06e-02	4.48e-02
TP53 Regulates Transcription of DNA Repair Genes	60	4.45e-02	1.14e-01	0.16500	1.22e-01	1.11e-01	1.02e-01	1.36e-01
Suppression of phagosomal maturation	13	4.46e-02	1.14e-01	0.43800	-2.73e-01	3.43e-01	8.79e-02	3.24e-02
Antiviral mechanism by IFN-stimulated genes	76	4.46e-02	1.14e-01	0.18100	-1.10e-01	1.44e-01	9.84e-02	2.95e-02
Interferon gamma signaling	69	4.48e-02	1.14e-01	0.16600	-1.66e-01	-1.54e-02	1.74e-02	8.25e-01
G alpha (q) signalling events	159	4.50e-02	1.14e-01	0.11600	-1.95e-02	1.15e-01	6.72e-01	1.28e-02
Protein folding	93	4.56e-02	1.16e-01	0.15200	-3.09e-02	1.49e-01	6.07e-01	1.30e-02
Regulation of localization of FOXO transcription factors	12	4.56e-02	1.16e-01	0.41100	-2.69e-02	4.10e-01	8.72e-01	1.40e-02
Mitochondrial tRNA aminoacylation	21	4.58e-02	1.16e-01	0.27800	-1.84e-01	-2.09e-01	1.45e-01	9.79e-02
Signaling by MET	66	4.60e-02	1.16e-01	0.18700	-7.02e-02	1.73e-01	3.24e-01	1.49e-02
Signaling by high-kinase activity BRAF mutants	33	4.67e-02	1.18e-01	0.25500	-5.30e-02	2.49e-01	5.98e-01	1.33e-02
Phase 0 - rapid depolarisation	24	4.70e-02	1.18e-01	0.31000	2.85e-01	-1.22e-01	1.58e-02	3.01e-01
Regulation of IFNG signaling	13	4.71e-02	1.18e-01	0.42200	-1.72e-01	3.85e-01	2.82e-01	1.62e-02
Lysosphingolipid and LPA receptors	13	4.81e-02	1.20e-01	0.40700	3.94e-01	-1.03e-01	1.39e-02	5.19e-01
PECAM1 interactions	12	4.87e-02	1.22e-01	0.40500	-2.03e-02	4.04e-01	9.03e-01	1.53e-02
Estrogen-dependent gene expression	97	4.88e-02	1.22e-01	0.14200	-5.73e-03	1.42e-01	9.22e-01	1.55e-02
Amyloid fiber formation	50	4.99e-02	1.24e-01	0.17800	1.29e-01	1.22e-01	1.15e-01	1.35e-01
Cargo trafficking to the periciliary membrane	47	5.01e-02	1.25e-01	0.20700	-2.06e-01	2.54e-02	1.48e-02	7.64e-01
Negative regulation of MAPK pathway	42	5.02e-02	1.25e-01	0.21100	1.29e-02	2.10e-01	8.85e-01	1.85e-02
Organic cation/anion/zwitterion transport	13	5.08e-02	1.26e-01	0.35200	-1.68e-01	-3.10e-01	2.95e-01	5.33e-02
Aberrant regulation of mitotic cell cycle due to RB1 defects	35	5.10e-02	1.26e-01	0.21600	1.94e-01	9.49e-02	4.76e-02	3.31e-01
Diseases of mitotic cell cycle	35	5.10e-02	1.26e-01	0.21600	1.94e-01	9.49e-02	4.76e-02	3.31e-01
Bicarbonate transporters	10	5.12e-02	1.26e-01	0.47100	4.37e-01	-1.77e-01	1.67e-02	3.34e-01
Signal transduction by L1	21	5.14e-02	1.26e-01	0.30500	-2.07e-02	3.04e-01	8.69e-01	1.59e-02
Ca2+ pathway	59	5.16e-02	1.27e-01	0.17000	4.61e-02	1.64e-01	5.40e-01	2.98e-02
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models	20	5.23e-02	1.28e-01	0.28100	2.39e-01	1.48e-01	6.40e-02	2.53e-01
Neurodegenerative Diseases	20	5.23e-02	1.28e-01	0.28100	2.39e-01	1.48e-01	6.40e-02	2.53e-01
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants	19	5.23e-02	1.28e-01	0.35300	-2.80e-01	2.15e-01	3.47e-02	1.05e-01
Signaling by Ligand-Responsive EGFR Variants in Cancer	19	5.23e-02	1.28e-01	0.35300	-2.80e-01	2.15e-01	3.47e-02	1.05e-01
Nuclear Events (kinase and transcription factor activation)	54	5.24e-02	1.28e-01	0.17200	8.64e-02	1.48e-01	2.72e-01	5.95e-02
Signaling by PDGFR in disease	19	5.29e-02	1.29e-01	0.34800	-1.76e-01	3.00e-01	1.85e-01	2.35e-02
Diseases associated with the TLR signaling cascade	22	5.35e-02	1.30e-01	0.32800	-2.11e-01	2.50e-01	8.62e-02	4.22e-02
Diseases of Immune System	22	5.35e-02	1.30e-01	0.32800	-2.11e-01	2.50e-01	8.62e-02	4.22e-02
Transcriptional Regulation by E2F6	34	5.38e-02	1.30e-01	0.25000	-7.56e-02	2.38e-01	4.46e-01	1.62e-02
ADORA2B mediated anti-inflammatory cytokines production	78	5.40e-02	1.30e-01	0.16100	-3.17e-02	1.58e-01	6.29e-01	1.57e-02
ABC transporters in lipid homeostasis	15	5.45e-02	1.31e-01	0.36700	3.60e-01	-7.27e-02	1.59e-02	6.26e-01
Glycerophospholipid biosynthesis	114	5.46e-02	1.31e-01	0.14000	1.27e-01	-5.97e-02	1.98e-02	2.72e-01
Glutathione synthesis and recycling	12	5.49e-02	1.32e-01	0.39200	-3.92e-01	-4.66e-03	1.89e-02	9.78e-01
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	11	5.53e-02	1.32e-01	0.44000	-4.15e-01	1.45e-01	1.72e-02	4.06e-01
Norepinephrine Neurotransmitter Release Cycle	15	5.58e-02	1.33e-01	0.38000	1.49e-01	-3.50e-01	3.18e-01	1.89e-02
Plasma lipoprotein remodeling	27	5.63e-02	1.34e-01	0.27100	2.67e-01	-4.67e-02	1.65e-02	6.75e-01
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer	44	5.64e-02	1.35e-01	0.22800	-1.30e-01	1.88e-01	1.37e-01	3.13e-02
Signaling by KIT in disease	20	5.71e-02	1.36e-01	0.32000	-8.29e-02	3.09e-01	5.21e-01	1.69e-02
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants	20	5.71e-02	1.36e-01	0.32000	-8.29e-02	3.09e-01	5.21e-01	1.69e-02
Extension of Telomeres	49	5.71e-02	1.36e-01	0.20700	1.96e-01	-6.67e-02	1.77e-02	4.20e-01
Regulation of pyruvate dehydrogenase (PDH) complex	15	5.75e-02	1.36e-01	0.36200	-6.57e-02	3.56e-01	6.60e-01	1.69e-02
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex	13	5.77e-02	1.36e-01	0.36400	5.00e-02	3.60e-01	7.55e-01	2.46e-02
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest	18	5.78e-02	1.37e-01	0.32700	3.24e-01	-4.24e-02	1.73e-02	7.55e-01
Regulation of TP53 Expression and Degradation	34	5.83e-02	1.37e-01	0.22700	1.82e-02	2.26e-01	8.55e-01	2.23e-02
IRE1alpha activates chaperones	50	5.86e-02	1.38e-01	0.20200	-1.94e-01	5.30e-02	1.74e-02	5.17e-01
MET activates RAS signaling	11	5.93e-02	1.39e-01	0.42800	-1.11e-01	4.13e-01	5.24e-01	1.76e-02
Glycogen breakdown (glycogenolysis)	14	5.93e-02	1.39e-01	0.33700	1.12e-01	3.18e-01	4.70e-01	3.95e-02
RNA Polymerase II Transcription Termination	62	5.97e-02	1.40e-01	0.17300	-1.72e-01	1.03e-02	1.90e-02	8.89e-01
mRNA 3'-end processing	54	6.09e-02	1.42e-01	0.19600	-1.84e-01	6.57e-02	1.93e-02	4.04e-01
Transcriptional regulation by small RNAs	56	6.26e-02	1.46e-01	0.17400	1.73e-01	1.85e-02	2.52e-02	8.11e-01
tRNA Aminoacylation	42	6.27e-02	1.46e-01	0.21100	-2.09e-01	2.89e-02	1.89e-02	7.46e-01
Assembly of collagen fibrils and other multimeric structures	44	6.43e-02	1.49e-01	0.19600	1.56e-02	1.96e-01	8.58e-01	2.48e-02
Regulation of TP53 Degradation	33	6.46e-02	1.50e-01	0.22100	4.71e-02	2.16e-01	6.40e-01	3.22e-02
Reduction of cytosolic Ca++ levels	11	6.57e-02	1.52e-01	0.36400	1.88e-01	3.12e-01	2.81e-01	7.28e-02
Phosphorylation of CD3 and TCR zeta chains	16	6.68e-02	1.54e-01	0.33300	-3.32e-01	2.15e-02	2.14e-02	8.81e-01
Mitochondrial Fatty Acid Beta-Oxidation	34	6.68e-02	1.54e-01	0.23800	-6.09e-02	2.30e-01	5.39e-01	2.02e-02
XBP1(S) activates chaperone genes	48	6.79e-02	1.56e-01	0.20100	-1.93e-01	5.43e-02	2.07e-02	5.15e-01
IKK complex recruitment mediated by RIP1	20	6.79e-02	1.56e-01	0.31900	-1.27e-01	2.92e-01	3.25e-01	2.38e-02
Listeria monocytogenes entry into host cells	19	7.00e-02	1.61e-01	0.33500	-2.65e-01	2.05e-01	4.53e-02	1.23e-01
Signal regulatory protein family interactions	12	7.02e-02	1.61e-01	0.36400	-3.59e-01	-5.83e-02	3.14e-02	7.26e-01
RNA polymerase II transcribes snRNA genes	71	7.15e-02	1.64e-01	0.15600	-1.10e-02	1.56e-01	8.73e-01	2.30e-02
Regulation of insulin secretion	69	7.16e-02	1.64e-01	0.14200	1.05e-01	9.52e-02	1.30e-01	1.72e-01
Telomere C-strand (Lagging Strand) Synthesis	33	7.21e-02	1.65e-01	0.24000	2.30e-01	-6.98e-02	2.24e-02	4.88e-01
Chaperone Mediated Autophagy	16	7.25e-02	1.65e-01	0.36400	-2.44e-01	2.70e-01	9.16e-02	6.12e-02
Activated NOTCH1 Transmits Signal to the Nucleus	29	7.30e-02	1.66e-01	0.26200	-2.38e-01	1.09e-01	2.66e-02	3.08e-01
Cardiac conduction	95	7.35e-02	1.67e-01	0.12100	9.69e-02	7.24e-02	1.03e-01	2.23e-01
MAP2K and MAPK activation	37	7.48e-02	1.70e-01	0.22100	-4.50e-02	2.16e-01	6.36e-01	2.28e-02
Budding and maturation of HIV virion	26	7.50e-02	1.70e-01	0.25500	-1.15e-02	2.54e-01	9.19e-01	2.49e-02
Pyruvate metabolism	28	7.57e-02	1.71e-01	0.26500	-1.15e-01	2.39e-01	2.91e-01	2.85e-02
Sialic acid metabolism	28	7.57e-02	1.71e-01	0.24900	-3.14e-02	2.47e-01	7.73e-01	2.36e-02
STING mediated induction of host immune responses	16	7.58e-02	1.71e-01	0.34500	-3.24e-01	1.19e-01	2.48e-02	4.12e-01
EGR2 and SOX10-mediated initiation of Schwann cell myelination	25	7.58e-02	1.71e-01	0.25500	8.64e-03	2.55e-01	9.40e-01	2.76e-02
Keratan sulfate biosynthesis	24	7.59e-02	1.71e-01	0.24300	1.03e-01	2.20e-01	3.83e-01	6.24e-02
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon	16	7.63e-02	1.71e-01	0.35300	-3.10e-01	1.68e-01	3.16e-02	2.45e-01
Digestion and absorption	13	7.67e-02	1.72e-01	0.33600	3.21e-01	9.75e-02	4.50e-02	5.43e-01
Gastrin-CREB signalling pathway via PKC and MAPK	17	7.70e-02	1.72e-01	0.33100	-9.92e-02	3.16e-01	4.79e-01	2.43e-02
Cleavage of the damaged pyrimidine	22	7.87e-02	1.75e-01	0.30300	2.48e-01	-1.75e-01	4.40e-02	1.56e-01
Depyrimidination	22	7.87e-02	1.75e-01	0.30300	2.48e-01	-1.75e-01	4.40e-02	1.56e-01
Recognition and association of DNA glycosylase with site containing an affected pyrimidine	22	7.87e-02	1.75e-01	0.30300	2.48e-01	-1.75e-01	4.40e-02	1.56e-01
Sema4D in semaphorin signaling	24	7.89e-02	1.75e-01	0.23700	1.35e-01	1.95e-01	2.53e-01	9.77e-02
Glucagon-type ligand receptors	23	7.97e-02	1.77e-01	0.26200	1.42e-02	2.61e-01	9.06e-01	3.00e-02
Cytochrome P450 - arranged by substrate type	46	7.98e-02	1.77e-01	0.17200	1.50e-01	8.49e-02	7.86e-02	3.19e-01
PD-1 signaling	16	7.99e-02	1.77e-01	0.31200	-3.11e-01	-2.66e-02	3.15e-02	8.54e-01
Fatty acyl-CoA biosynthesis	29	8.05e-02	1.78e-01	0.25400	-9.18e-02	2.37e-01	3.92e-01	2.71e-02
Advanced glycosylation endproduct receptor signaling	11	8.06e-02	1.78e-01	0.40400	-1.07e-01	3.90e-01	5.38e-01	2.51e-02
Processive synthesis on the C-strand of the telomere	18	8.13e-02	1.79e-01	0.29200	2.90e-01	3.15e-02	3.33e-02	8.17e-01
Sphingolipid metabolism	81	8.14e-02	1.79e-01	0.14700	-1.44e-01	3.04e-02	2.51e-02	6.36e-01
Glycogen metabolism	26	8.26e-02	1.81e-01	0.23900	3.86e-02	2.36e-01	7.33e-01	3.71e-02
Erythropoietin activates RAS	14	8.33e-02	1.82e-01	0.35600	-9.51e-02	3.43e-01	5.38e-01	2.61e-02
Eicosanoids	10	8.37e-02	1.83e-01	0.40600	4.04e-01	-3.81e-02	2.70e-02	8.35e-01
Arachidonic acid metabolism	45	8.51e-02	1.86e-01	0.17000	1.17e-01	1.23e-01	1.74e-01	1.54e-01
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	11	8.52e-02	1.86e-01	0.40100	3.85e-01	-1.10e-01	2.69e-02	5.28e-01
Acetylcholine Neurotransmitter Release Cycle	11	8.60e-02	1.87e-01	0.41700	2.10e-01	-3.61e-01	2.27e-01	3.84e-02
Transcriptional regulation of pluripotent stem cells	16	8.62e-02	1.87e-01	0.28500	2.35e-01	1.62e-01	1.04e-01	2.61e-01
DAP12 interactions	34	8.62e-02	1.87e-01	0.24100	-1.79e-01	1.63e-01	7.16e-02	1.01e-01
Sealing of the nuclear envelope (NE) by ESCRT-III	23	8.65e-02	1.87e-01	0.27400	-6.23e-02	2.66e-01	6.05e-01	2.70e-02
Phase I - Functionalization of compounds	85	8.68e-02	1.88e-01	0.12400	7.07e-02	1.02e-01	2.60e-01	1.05e-01
Constitutive Signaling by EGFRvIII	15	8.70e-02	1.88e-01	0.36100	-2.90e-01	2.15e-01	5.21e-02	1.49e-01
Signaling by EGFRvIII in Cancer	15	8.70e-02	1.88e-01	0.36100	-2.90e-01	2.15e-01	5.21e-02	1.49e-01
Nuclear Envelope Breakdown	53	8.76e-02	1.89e-01	0.16600	1.64e-01	2.65e-02	3.93e-02	7.39e-01
GRB2:SOS provides linkage to MAPK signaling for Integrins	15	8.83e-02	1.90e-01	0.30100	1.03e-01	2.83e-01	4.89e-01	5.78e-02
DNA Repair	280	8.88e-02	1.90e-01	0.07140	6.92e-02	1.74e-02	4.68e-02	6.16e-01
Synthesis of Leukotrienes (LT) and Eoxins (EX)	18	8.88e-02	1.90e-01	0.27700	2.65e-01	8.07e-02	5.17e-02	5.54e-01
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	19	8.90e-02	1.90e-01	0.27600	4.09e-02	2.73e-01	7.58e-01	3.91e-02
Signaling by BMP	23	8.97e-02	1.92e-01	0.25100	3.42e-02	2.49e-01	7.77e-01	3.86e-02
Interleukin-6 signaling	10	8.98e-02	1.92e-01	0.43700	-2.43e-01	3.63e-01	1.84e-01	4.66e-02
DCC mediated attractive signaling	13	9.10e-02	1.94e-01	0.38400	-3.05e-01	2.34e-01	5.68e-02	1.45e-01
tRNA modification in the nucleus and cytosol	43	9.12e-02	1.94e-01	0.18900	-7.46e-06	-1.89e-01	1.00e+00	3.24e-02
Activation of PPARGC1A (PGC-1alpha) by phosphorylation	10	9.13e-02	1.94e-01	0.40600	3.99e-01	-7.38e-02	2.87e-02	6.86e-01
PI Metabolism	82	9.13e-02	1.94e-01	0.14500	-3.75e-02	1.40e-01	5.58e-01	2.89e-02
ISG15 antiviral mechanism	68	9.16e-02	1.94e-01	0.16400	-7.21e-02	1.48e-01	3.04e-01	3.54e-02
Interleukin receptor SHC signaling	22	9.22e-02	1.95e-01	0.28600	-2.62e-01	1.16e-01	3.36e-02	3.45e-01
InlB-mediated entry of Listeria monocytogenes into host cell	14	9.23e-02	1.95e-01	0.36700	-3.05e-01	2.05e-01	4.81e-02	1.85e-01
Signaling by ERBB4	52	9.28e-02	1.96e-01	0.19000	-9.73e-02	1.63e-01	2.25e-01	4.26e-02
Regulation of innate immune responses to cytosolic DNA	15	9.32e-02	1.96e-01	0.33000	-3.25e-01	5.68e-02	2.95e-02	7.04e-01
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	10	9.42e-02	1.98e-01	0.35200	-2.55e-01	-2.43e-01	1.63e-01	1.83e-01
Processing and activation of SUMO	10	9.43e-02	1.98e-01	0.42500	-1.87e-01	3.82e-01	3.07e-01	3.65e-02
Interleukin-17 signaling	66	9.49e-02	1.99e-01	0.14500	2.79e-02	1.43e-01	6.96e-01	4.52e-02
Cyclin D associated events in G1	46	9.54e-02	1.99e-01	0.16700	7.38e-02	1.50e-01	3.87e-01	7.86e-02
G1 Phase	46	9.54e-02	1.99e-01	0.16700	7.38e-02	1.50e-01	3.87e-01	7.86e-02
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	12	9.60e-02	2.00e-01	0.39500	-3.15e-01	2.39e-01	5.88e-02	1.52e-01
Aspartate and asparagine metabolism	11	9.62e-02	2.00e-01	0.34100	1.49e-01	3.07e-01	3.93e-01	7.81e-02
G beta:gamma signalling through CDC42	18	9.68e-02	2.01e-01	0.28500	1.29e-02	2.85e-01	9.24e-01	3.66e-02
Cell junction organization	76	9.71e-02	2.02e-01	0.13000	5.43e-02	1.18e-01	4.14e-01	7.51e-02
SUMOylation of DNA damage response and repair proteins	75	9.84e-02	2.04e-01	0.12900	6.65e-02	1.11e-01	3.19e-01	9.80e-02
MHC class II antigen presentation	95	9.87e-02	2.04e-01	0.13600	-5.69e-02	1.24e-01	3.38e-01	3.69e-02
SUMOylation of transcription cofactors	42	9.90e-02	2.05e-01	0.20200	-1.89e-01	7.14e-02	3.40e-02	4.23e-01
Processing of Capped Intronless Pre-mRNA	25	1.01e-01	2.09e-01	0.22300	-1.96e-01	-1.07e-01	9.07e-02	3.56e-01
The role of Nef in HIV-1 replication and disease pathogenesis	27	1.02e-01	2.10e-01	0.25900	-1.44e-01	2.16e-01	1.97e-01	5.24e-02
Miscellaneous transport and binding events	23	1.03e-01	2.13e-01	0.27800	-2.40e-01	1.41e-01	4.67e-02	2.43e-01
Aquaporin-mediated transport	44	1.04e-01	2.13e-01	0.16500	1.19e-01	1.14e-01	1.73e-01	1.90e-01
Synthesis of PIPs at the early endosome membrane	16	1.04e-01	2.13e-01	0.33800	-2.19e-01	2.58e-01	1.30e-01	7.42e-02
Signaling by EGFR in Cancer	22	1.04e-01	2.13e-01	0.28800	-2.15e-01	1.92e-01	8.10e-02	1.18e-01
IRF3-mediated induction of type I IFN	13	1.04e-01	2.13e-01	0.36700	-3.23e-01	1.73e-01	4.35e-02	2.79e-01
p130Cas linkage to MAPK signaling for integrins	15	1.05e-01	2.14e-01	0.28400	1.49e-01	2.42e-01	3.18e-01	1.05e-01
Diseases of programmed cell death	26	1.05e-01	2.14e-01	0.21700	1.92e-01	1.01e-01	9.02e-02	3.72e-01
Spry regulation of FGF signaling	16	1.05e-01	2.14e-01	0.32200	-1.06e-01	3.04e-01	4.62e-01	3.55e-02
Regulation of TP53 Activity through Phosphorylation	90	1.06e-01	2.15e-01	0.11600	6.25e-02	9.75e-02	3.06e-01	1.10e-01
Apoptotic factor-mediated response	14	1.07e-01	2.16e-01	0.29000	1.93e-01	2.16e-01	2.10e-01	1.61e-01
MECP2 regulates neuronal receptors and channels	15	1.07e-01	2.17e-01	0.30300	2.68e-02	3.01e-01	8.57e-01	4.33e-02
Mitochondrial protein import	61	1.09e-01	2.22e-01	0.14000	1.23e-01	6.78e-02	9.76e-02	3.60e-01
TICAM1, RIP1-mediated IKK complex recruitment	17	1.10e-01	2.22e-01	0.31000	-1.09e-01	2.90e-01	4.35e-01	3.82e-02
HDACs deacetylate histones	40	1.10e-01	2.22e-01	0.19600	-3.70e-02	1.92e-01	6.85e-01	3.57e-02
Translation of structural proteins	28	1.11e-01	2.24e-01	0.24900	-2.10e-01	1.34e-01	5.46e-02	2.20e-01
Trafficking and processing of endosomal TLR	11	1.12e-01	2.25e-01	0.39900	-2.33e-01	3.23e-01	1.81e-01	6.32e-02
Transcriptional regulation of granulopoiesis	38	1.13e-01	2.28e-01	0.17700	8.06e-02	1.57e-01	3.90e-01	9.38e-02
Signaling by NOTCH1	71	1.14e-01	2.28e-01	0.15600	-8.49e-02	1.31e-01	2.16e-01	5.70e-02
Deadenylation of mRNA	22	1.14e-01	2.28e-01	0.28000	-2.33e-01	1.54e-01	5.83e-02	2.10e-01
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	28	1.15e-01	2.30e-01	0.20200	1.52e-01	1.33e-01	1.64e-01	2.25e-01
Formation of TC-NER Pre-Incision Complex	53	1.15e-01	2.30e-01	0.16300	-8.04e-03	1.63e-01	9.19e-01	4.03e-02
Lagging Strand Synthesis	19	1.15e-01	2.30e-01	0.26600	2.65e-01	1.76e-02	4.56e-02	8.95e-01
SARS-CoV-2 Infection	63	1.16e-01	2.32e-01	0.16600	-1.02e-01	1.31e-01	1.62e-01	7.28e-02
Late endosomal microautophagy	29	1.17e-01	2.33e-01	0.21500	1.07e-02	2.15e-01	9.21e-01	4.54e-02
RUNX2 regulates osteoblast differentiation	22	1.18e-01	2.36e-01	0.24100	3.60e-02	2.39e-01	7.70e-01	5.28e-02
Sema4D induced cell migration and growth-cone collapse	20	1.19e-01	2.36e-01	0.23900	2.05e-01	1.24e-01	1.13e-01	3.38e-01
Death Receptor Signalling	135	1.19e-01	2.36e-01	0.10600	-2.62e-02	1.03e-01	5.99e-01	3.93e-02
Interactions of Vpr with host cellular proteins	36	1.20e-01	2.38e-01	0.17900	1.60e-01	7.97e-02	9.57e-02	4.08e-01
Signaling by PDGFRA extracellular domain mutants	12	1.21e-01	2.38e-01	0.33500	2.31e-03	3.35e-01	9.89e-01	4.48e-02
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants	12	1.21e-01	2.38e-01	0.33500	2.31e-03	3.35e-01	9.89e-01	4.48e-02
ADP signalling through P2Y purinoceptor 12	19	1.21e-01	2.38e-01	0.26700	-3.23e-03	2.67e-01	9.81e-01	4.40e-02
SLC transporter disorders	90	1.21e-01	2.38e-01	0.13800	8.80e-02	-1.06e-01	1.49e-01	8.25e-02
Retrograde transport at the Trans-Golgi-Network	45	1.21e-01	2.38e-01	0.17800	-2.56e-02	1.77e-01	7.67e-01	4.04e-02
Defects in vitamin and cofactor metabolism	21	1.21e-01	2.38e-01	0.24500	-2.42e-01	-3.96e-02	5.52e-02	7.54e-01
Killing mechanisms	11	1.22e-01	2.39e-01	0.38900	2.14e-01	-3.25e-01	2.18e-01	6.23e-02
WNT5:FZD7-mediated leishmania damping	11	1.22e-01	2.39e-01	0.38900	2.14e-01	-3.25e-01	2.18e-01	6.23e-02
Ca-dependent events	35	1.24e-01	2.43e-01	0.18000	8.70e-02	1.57e-01	3.73e-01	1.08e-01
Signaling by Leptin	10	1.25e-01	2.45e-01	0.35000	3.44e-01	6.60e-02	5.96e-02	7.18e-01
Assembly of active LPL and LIPC lipase complexes	16	1.25e-01	2.45e-01	0.32000	2.70e-01	-1.72e-01	6.16e-02	2.35e-01
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template	37	1.26e-01	2.45e-01	0.17200	1.07e-01	1.35e-01	2.62e-01	1.55e-01
Activation of the AP-1 family of transcription factors	10	1.26e-01	2.45e-01	0.39000	-1.33e-01	3.67e-01	4.68e-01	4.43e-02
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	13	1.26e-01	2.45e-01	0.34700	3.17e-01	-1.39e-01	4.76e-02	3.85e-01
Positive epigenetic regulation of rRNA expression	52	1.27e-01	2.46e-01	0.17600	-8.92e-02	1.52e-01	2.66e-01	5.76e-02
Nuclear Pore Complex (NPC) Disassembly	36	1.27e-01	2.46e-01	0.18300	1.78e-01	4.06e-02	6.40e-02	6.74e-01
Constitutive Signaling by Overexpressed ERBB2	11	1.28e-01	2.46e-01	0.36400	-8.72e-02	3.53e-01	6.17e-01	4.25e-02
Polymerase switching on the C-strand of the telomere	25	1.28e-01	2.46e-01	0.25600	2.08e-01	-1.50e-01	7.19e-02	1.94e-01
SIRT1 negatively regulates rRNA expression	17	1.28e-01	2.46e-01	0.25400	2.15e-01	1.37e-01	1.26e-01	3.29e-01
Cytochrome c-mediated apoptotic response	11	1.28e-01	2.46e-01	0.33300	5.83e-02	3.28e-01	7.38e-01	5.96e-02
MET receptor recycling	10	1.28e-01	2.46e-01	0.37200	-3.69e-01	4.85e-02	4.33e-02	7.91e-01
Post-chaperonin tubulin folding pathway	17	1.30e-01	2.49e-01	0.28100	-2.22e-02	2.81e-01	8.74e-01	4.53e-02
Triglyceride catabolism	18	1.31e-01	2.51e-01	0.24400	1.53e-01	1.90e-01	2.61e-01	1.62e-01
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	72	1.31e-01	2.51e-01	0.13500	-1.35e-01	2.97e-03	4.79e-02	9.65e-01
HCMV Early Events	67	1.32e-01	2.52e-01	0.12600	9.04e-02	8.84e-02	2.01e-01	2.11e-01
Cyclin A/B1/B2 associated events during G2/M transition	24	1.34e-01	2.56e-01	0.22300	2.19e-01	4.17e-02	6.37e-02	7.24e-01
Collagen formation	75	1.35e-01	2.58e-01	0.13300	-1.07e-02	1.33e-01	8.73e-01	4.73e-02
GAB1 signalosome	14	1.36e-01	2.59e-01	0.30700	-3.06e-01	2.80e-02	4.75e-02	8.56e-01
YAP1- and WWTR1 (TAZ)-stimulated gene expression	12	1.36e-01	2.59e-01	0.36600	-2.42e-01	2.75e-01	1.47e-01	9.90e-02
Metabolism of lipids	660	1.36e-01	2.59e-01	0.04390	4.39e-03	4.37e-02	8.48e-01	5.72e-02
Integration of energy metabolism	98	1.36e-01	2.59e-01	0.10400	8.53e-02	5.99e-02	1.45e-01	3.06e-01
PI3K/AKT Signaling in Cancer	87	1.37e-01	2.60e-01	0.13600	-1.02e-01	9.07e-02	1.02e-01	1.44e-01
PERK regulates gene expression	30	1.37e-01	2.60e-01	0.22800	-1.18e-01	1.95e-01	2.64e-01	6.45e-02
NGF-stimulated transcription	33	1.38e-01	2.61e-01	0.17900	1.53e-01	9.45e-02	1.30e-01	3.48e-01
G-protein activation	24	1.39e-01	2.62e-01	0.22400	2.49e-02	2.22e-01	8.33e-01	5.93e-02
Gene Silencing by RNA	79	1.40e-01	2.64e-01	0.13100	1.29e-01	-2.36e-02	4.75e-02	7.17e-01
HuR (ELAVL1) binds and stabilizes mRNA	10	1.40e-01	2.64e-01	0.39300	-2.06e-01	3.34e-01	2.58e-01	6.72e-02
NOTCH1 Intracellular Domain Regulates Transcription	47	1.41e-01	2.65e-01	0.16100	1.27e-02	1.60e-01	8.80e-01	5.78e-02
Transcription of E2F targets under negative control by DREAM complex	19	1.41e-01	2.65e-01	0.26000	-1.58e-02	2.59e-01	9.05e-01	5.06e-02
Peptide ligand-binding receptors	110	1.42e-01	2.67e-01	0.11300	-3.10e-02	1.09e-01	5.75e-01	4.90e-02
SUMOylation	165	1.43e-01	2.67e-01	0.09600	-4.58e-02	8.44e-02	3.11e-01	6.17e-02
Cytosolic sensors of pathogen-associated DNA	61	1.43e-01	2.67e-01	0.16000	-1.31e-01	9.14e-02	7.76e-02	2.17e-01
Interferon Signaling	168	1.44e-01	2.69e-01	0.09700	-6.95e-02	6.77e-02	1.21e-01	1.31e-01
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases	14	1.45e-01	2.69e-01	0.32100	-1.18e-01	2.98e-01	4.45e-01	5.32e-02
Transport of vitamins, nucleosides, and related molecules	34	1.45e-01	2.69e-01	0.21400	1.68e-01	-1.32e-01	8.95e-02	1.84e-01
EPHA-mediated growth cone collapse	15	1.46e-01	2.71e-01	0.28500	3.05e-03	2.85e-01	9.84e-01	5.57e-02
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism	11	1.46e-01	2.72e-01	0.30500	2.56e-01	1.66e-01	1.42e-01	3.39e-01
Keratan sulfate degradation	10	1.47e-01	2.73e-01	0.34200	3.77e-02	3.40e-01	8.36e-01	6.30e-02
Fatty acids	11	1.47e-01	2.73e-01	0.36000	3.35e-01	-1.31e-01	5.42e-02	4.52e-01
Synthesis of bile acids and bile salts	27	1.48e-01	2.74e-01	0.19600	9.17e-02	1.73e-01	4.10e-01	1.20e-01
p75NTR recruits signalling complexes	13	1.49e-01	2.75e-01	0.34100	-2.81e-01	1.94e-01	7.97e-02	2.26e-01
Glycogen synthesis	15	1.49e-01	2.75e-01	0.27400	5.05e-02	2.69e-01	7.35e-01	7.10e-02
Branched-chain amino acid catabolism	21	1.51e-01	2.78e-01	0.26300	-2.34e-01	1.20e-01	6.29e-02	3.40e-01
Ovarian tumor domain proteases	37	1.51e-01	2.78e-01	0.18300	-1.04e-02	1.83e-01	9.13e-01	5.48e-02
Basigin interactions	24	1.52e-01	2.79e-01	0.21200	2.02e-01	6.25e-02	8.65e-02	5.96e-01
TAK1 activates NFkB by phosphorylation and activation of IKKs complex	24	1.52e-01	2.79e-01	0.20700	9.60e-02	1.83e-01	4.16e-01	1.21e-01
CD209 (DC-SIGN) signaling	19	1.53e-01	2.80e-01	0.28000	-1.60e-01	2.30e-01	2.26e-01	8.27e-02
Intrinsic Pathway of Fibrin Clot Formation	16	1.56e-01	2.85e-01	0.24700	1.70e-01	1.80e-01	2.39e-01	2.14e-01
Transport of bile salts and organic acids, metal ions and amine compounds	76	1.58e-01	2.89e-01	0.12400	-2.99e-03	-1.24e-01	9.64e-01	6.19e-02
RNA Pol II CTD phosphorylation and interaction with CE	27	1.61e-01	2.94e-01	0.19200	8.24e-02	1.74e-01	4.59e-01	1.18e-01
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection	27	1.61e-01	2.94e-01	0.19200	8.24e-02	1.74e-01	4.59e-01	1.18e-01
Homologous DNA Pairing and Strand Exchange	42	1.63e-01	2.97e-01	0.15800	1.54e-01	3.86e-02	8.52e-02	6.65e-01
Signal amplification	29	1.63e-01	2.97e-01	0.21200	-6.03e-02	2.04e-01	5.74e-01	5.78e-02
Signaling by Erythropoietin	25	1.64e-01	2.98e-01	0.24100	-1.44e-01	1.93e-01	2.12e-01	9.58e-02
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1	16	1.65e-01	2.99e-01	0.25600	6.22e-02	2.48e-01	6.67e-01	8.61e-02
Early Phase of HIV Life Cycle	14	1.65e-01	2.99e-01	0.29900	-5.86e-02	2.93e-01	7.04e-01	5.78e-02
Rab regulation of trafficking	117	1.66e-01	3.00e-01	0.10500	-2.60e-02	1.01e-01	6.28e-01	5.82e-02
Presynaptic phase of homologous DNA pairing and strand exchange	39	1.67e-01	3.02e-01	0.15700	1.32e-01	8.49e-02	1.55e-01	3.59e-01
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	36	1.68e-01	3.02e-01	0.19500	-1.75e-01	8.72e-02	6.97e-02	3.65e-01
SUMO E3 ligases SUMOylate target proteins	159	1.68e-01	3.02e-01	0.09370	-4.44e-02	8.24e-02	3.34e-01	7.32e-02
CREB1 phosphorylation through the activation of Adenylate Cyclase	11	1.68e-01	3.02e-01	0.32200	-3.61e-03	3.22e-01	9.83e-01	6.43e-02
Signaling by FGFR2 IIIa TM	19	1.69e-01	3.04e-01	0.22500	1.04e-01	2.00e-01	4.35e-01	1.31e-01
RNA Polymerase I Promoter Opening	12	1.70e-01	3.04e-01	0.28200	1.45e-01	2.42e-01	3.85e-01	1.47e-01
Meiosis	60	1.70e-01	3.05e-01	0.12600	1.05e-01	6.95e-02	1.61e-01	3.52e-01
Metabolism of steroid hormones	23	1.70e-01	3.05e-01	0.20200	-1.61e-01	-1.22e-01	1.82e-01	3.10e-01
Inhibition of DNA recombination at telomere	28	1.71e-01	3.05e-01	0.18700	1.74e-01	6.98e-02	1.11e-01	5.23e-01
MET promotes cell motility	29	1.73e-01	3.08e-01	0.20700	-5.08e-02	2.01e-01	6.36e-01	6.12e-02
Insulin processing	25	1.74e-01	3.08e-01	0.23200	-1.06e-01	2.07e-01	3.58e-01	7.38e-02
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants	57	1.74e-01	3.08e-01	0.14900	-4.20e-02	1.43e-01	5.84e-01	6.25e-02
Constitutive Signaling by NOTCH1 PEST Domain Mutants	57	1.74e-01	3.08e-01	0.14900	-4.20e-02	1.43e-01	5.84e-01	6.25e-02
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer	57	1.74e-01	3.08e-01	0.14900	-4.20e-02	1.43e-01	5.84e-01	6.25e-02
Signaling by NOTCH1 PEST Domain Mutants in Cancer	57	1.74e-01	3.08e-01	0.14900	-4.20e-02	1.43e-01	5.84e-01	6.25e-02
Signaling by NOTCH1 in Cancer	57	1.74e-01	3.08e-01	0.14900	-4.20e-02	1.43e-01	5.84e-01	6.25e-02
Bile acid and bile salt metabolism	33	1.74e-01	3.08e-01	0.16900	8.76e-02	1.44e-01	3.84e-01	1.52e-01
Rho GTPase cycle	134	1.74e-01	3.08e-01	0.09560	-1.95e-02	9.36e-02	6.97e-01	6.17e-02
HDR through Single Strand Annealing (SSA)	37	1.75e-01	3.08e-01	0.16100	1.48e-01	6.42e-02	1.19e-01	4.99e-01
TICAM1-dependent activation of IRF3/IRF7	12	1.75e-01	3.08e-01	0.32400	-3.10e-01	9.42e-02	6.30e-02	5.72e-01
RHO GTPases Activate NADPH Oxidases	21	1.77e-01	3.11e-01	0.24000	-2.35e-01	5.19e-02	6.25e-02	6.81e-01
Downstream signal transduction	29	1.77e-01	3.11e-01	0.21700	-1.11e-01	1.86e-01	3.02e-01	8.30e-02
Meiotic recombination	34	1.78e-01	3.12e-01	0.16900	1.60e-01	5.57e-02	1.07e-01	5.75e-01
Uptake and function of anthrax toxins	10	1.78e-01	3.12e-01	0.32100	3.17e-01	5.11e-02	8.26e-02	7.80e-01
Signaling by FGFR3	34	1.79e-01	3.12e-01	0.19900	-9.67e-02	1.74e-01	3.29e-01	8.01e-02
Purine salvage	12	1.79e-01	3.12e-01	0.32500	-3.07e-01	1.07e-01	6.60e-02	5.23e-01
SUMOylation of ubiquitinylation proteins	38	1.79e-01	3.12e-01	0.16300	1.58e-01	3.66e-02	9.10e-02	6.96e-01
Signaling by FGFR1	41	1.79e-01	3.12e-01	0.18400	-1.30e-01	1.30e-01	1.49e-01	1.49e-01
RAF-independent MAPK1/3 activation	22	1.81e-01	3.16e-01	0.22600	-1.62e-02	2.25e-01	8.95e-01	6.73e-02
SARS-CoV-1 Infection	46	1.82e-01	3.17e-01	0.16300	-4.52e-02	1.57e-01	5.96e-01	6.58e-02
Signaling by FGFR4	33	1.82e-01	3.17e-01	0.20300	-1.20e-01	1.64e-01	2.32e-01	1.04e-01
DNA Damage Recognition in GG-NER	38	1.85e-01	3.21e-01	0.16800	3.44e-03	1.68e-01	9.71e-01	7.38e-02
Interleukin-35 Signalling	11	1.85e-01	3.21e-01	0.35200	-2.62e-01	2.35e-01	1.32e-01	1.78e-01
Transport of small molecules	634	1.85e-01	3.21e-01	0.04180	4.18e-02	1.05e-03	7.43e-02	9.64e-01
TP53 Regulates Transcription of Cell Death Genes	36	1.85e-01	3.21e-01	0.19000	-1.69e-01	8.58e-02	7.87e-02	3.73e-01
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells	14	1.86e-01	3.21e-01	0.25200	1.63e-01	1.92e-01	2.90e-01	2.15e-01
G2/M DNA damage checkpoint	61	1.89e-01	3.27e-01	0.12700	2.23e-02	1.26e-01	7.63e-01	9.02e-02
G alpha (i) signalling events	281	1.90e-01	3.27e-01	0.05630	3.80e-02	4.15e-02	2.75e-01	2.32e-01
Leading Strand Synthesis	13	1.90e-01	3.27e-01	0.28100	2.81e-01	1.82e-02	7.95e-02	9.09e-01
Polymerase switching	13	1.90e-01	3.27e-01	0.28100	2.81e-01	1.82e-02	7.95e-02	9.09e-01
G0 and Early G1	26	1.91e-01	3.29e-01	0.18500	9.09e-02	1.61e-01	4.23e-01	1.54e-01
Cholesterol biosynthesis	24	1.92e-01	3.29e-01	0.23400	1.92e-01	-1.33e-01	1.03e-01	2.59e-01
LGI-ADAM interactions	12	1.92e-01	3.29e-01	0.33100	1.92e-01	-2.70e-01	2.51e-01	1.05e-01
Ion channel transport	149	1.92e-01	3.29e-01	0.07710	4.40e-02	6.33e-02	3.55e-01	1.83e-01
Constitutive Signaling by Aberrant PI3K in Cancer	60	1.92e-01	3.29e-01	0.14700	-1.25e-01	7.82e-02	9.46e-02	2.95e-01
WNT5A-dependent internalization of FZD2, FZD5 and ROR2	13	1.94e-01	3.31e-01	0.28500	-6.03e-03	2.85e-01	9.70e-01	7.53e-02
Fertilization	15	1.95e-01	3.32e-01	0.27700	6.13e-02	-2.70e-01	6.81e-01	7.05e-02
Pre-NOTCH Transcription and Translation	41	1.95e-01	3.32e-01	0.14800	1.33e-01	6.51e-02	1.42e-01	4.71e-01
Abortive elongation of HIV-1 transcript in the absence of Tat	23	1.95e-01	3.32e-01	0.19300	1.35e-01	1.38e-01	2.61e-01	2.52e-01
SUMOylation of SUMOylation proteins	35	1.95e-01	3.32e-01	0.15800	1.34e-01	8.41e-02	1.71e-01	3.89e-01
Metabolism of nucleotides	93	1.96e-01	3.33e-01	0.10800	1.08e-01	-1.16e-02	7.28e-02	8.46e-01
Class C/3 (Metabotropic glutamate/pheromone receptors)	12	1.96e-01	3.33e-01	0.32000	1.26e-01	-2.94e-01	4.51e-01	7.81e-02
Inwardly rectifying K+ channels	28	1.98e-01	3.35e-01	0.21100	-9.53e-02	1.88e-01	3.83e-01	8.47e-02
Prostacyclin signalling through prostacyclin receptor	17	1.99e-01	3.36e-01	0.25400	-3.93e-02	2.51e-01	7.79e-01	7.27e-02
Degradation of the extracellular matrix	86	1.99e-01	3.36e-01	0.10100	4.66e-02	8.98e-02	4.55e-01	1.50e-01
Disorders of transmembrane transporters	163	2.01e-01	3.39e-01	0.07950	-7.95e-02	-6.95e-04	8.04e-02	9.88e-01
NOTCH4 Activation and Transmission of Signal to the Nucleus	10	2.02e-01	3.41e-01	0.35900	-2.43e-01	2.64e-01	1.83e-01	1.48e-01
Zinc transporters	16	2.03e-01	3.41e-01	0.25600	-2.55e-01	1.58e-02	7.73e-02	9.13e-01
SUMOylation of DNA replication proteins	46	2.05e-01	3.44e-01	0.13600	7.52e-02	1.13e-01	3.78e-01	1.85e-01
Epigenetic regulation of gene expression	93	2.05e-01	3.45e-01	0.11200	-3.41e-02	1.06e-01	5.71e-01	7.69e-02
G alpha (z) signalling events	44	2.06e-01	3.46e-01	0.15800	-3.31e-02	1.55e-01	7.04e-01	7.56e-02
Integrin signaling	27	2.07e-01	3.46e-01	0.18500	3.77e-02	1.81e-01	7.34e-01	1.03e-01
Generation of second messenger molecules	27	2.07e-01	3.46e-01	0.20400	-1.97e-01	5.35e-02	7.63e-02	6.31e-01
Post NMDA receptor activation events	60	2.07e-01	3.46e-01	0.11900	1.02e-01	6.15e-02	1.73e-01	4.10e-01
RUNX2 regulates bone development	29	2.08e-01	3.46e-01	0.16900	1.15e-01	1.24e-01	2.85e-01	2.48e-01
Presynaptic depolarization and calcium channel opening	11	2.08e-01	3.46e-01	0.32500	1.12e-01	-3.05e-01	5.20e-01	8.00e-02
Receptor Mediated Mitophagy	11	2.08e-01	3.47e-01	0.33500	-1.80e-01	2.83e-01	3.02e-01	1.04e-01
Negative regulators of DDX58/IFIH1 signaling	32	2.09e-01	3.47e-01	0.19900	-1.26e-01	1.53e-01	2.17e-01	1.33e-01
NS1 Mediated Effects on Host Pathways	38	2.09e-01	3.47e-01	0.15000	6.61e-02	1.35e-01	4.81e-01	1.51e-01
G alpha (12/13) signalling events	76	2.09e-01	3.47e-01	0.11800	-1.42e-02	1.17e-01	8.31e-01	7.81e-02
Processing of Intronless Pre-mRNAs	17	2.11e-01	3.49e-01	0.24500	-2.44e-01	1.40e-02	8.13e-02	9.20e-01
Triglyceride metabolism	30	2.12e-01	3.51e-01	0.17200	1.65e-01	4.93e-02	1.19e-01	6.40e-01
Signalling to RAS	19	2.12e-01	3.51e-01	0.24500	-8.11e-02	2.31e-01	5.41e-01	8.14e-02
EGFR downregulation	27	2.13e-01	3.52e-01	0.21200	-1.82e-01	1.09e-01	1.02e-01	3.27e-01
Activation of GABAB receptors	37	2.14e-01	3.53e-01	0.17100	-3.81e-02	1.67e-01	6.88e-01	7.92e-02
GABA B receptor activation	37	2.14e-01	3.53e-01	0.17100	-3.81e-02	1.67e-01	6.88e-01	7.92e-02
HDR through Homologous Recombination (HRR)	65	2.15e-01	3.54e-01	0.11300	1.00e-01	5.34e-02	1.63e-01	4.56e-01
Diseases associated with glycosaminoglycan metabolism	38	2.16e-01	3.55e-01	0.14900	6.20e-02	1.35e-01	5.09e-01	1.49e-01
Estrogen-dependent nuclear events downstream of ESR-membrane signaling	21	2.16e-01	3.55e-01	0.22700	-5.38e-02	2.20e-01	6.70e-01	8.03e-02
Keratan sulfate/keratin metabolism	29	2.17e-01	3.55e-01	0.17100	6.45e-02	1.59e-01	5.48e-01	1.39e-01
Membrane binding and targetting of GAG proteins	14	2.18e-01	3.56e-01	0.27100	-3.30e-02	2.69e-01	8.31e-01	8.19e-02
Synthesis And Processing Of GAG, GAGPOL Polyproteins	14	2.18e-01	3.56e-01	0.27100	-3.30e-02	2.69e-01	8.31e-01	8.19e-02
Mitophagy	27	2.18e-01	3.56e-01	0.21400	-1.43e-01	1.59e-01	1.99e-01	1.54e-01
Rap1 signalling	15	2.18e-01	3.56e-01	0.28100	-1.39e-01	2.44e-01	3.51e-01	1.01e-01
Cleavage of the damaged purine	17	2.19e-01	3.56e-01	0.26800	2.13e-01	-1.62e-01	1.28e-01	2.48e-01
Depurination	17	2.19e-01	3.56e-01	0.26800	2.13e-01	-1.62e-01	1.28e-01	2.48e-01
Recognition and association of DNA glycosylase with site containing an affected purine	17	2.19e-01	3.56e-01	0.26800	2.13e-01	-1.62e-01	1.28e-01	2.48e-01
Adrenaline,noradrenaline inhibits insulin secretion	26	2.20e-01	3.58e-01	0.18300	1.77e-01	4.75e-02	1.19e-01	6.75e-01
GABA receptor activation	48	2.21e-01	3.58e-01	0.14700	-2.59e-02	1.45e-01	7.56e-01	8.23e-02
mRNA Capping	29	2.23e-01	3.62e-01	0.17900	1.40e-02	1.78e-01	8.96e-01	9.70e-02
Termination of translesion DNA synthesis	31	2.24e-01	3.63e-01	0.16200	1.44e-01	7.34e-02	1.64e-01	4.80e-01
NOD1/2 Signaling Pathway	29	2.24e-01	3.63e-01	0.18500	-1.84e-02	1.84e-01	8.64e-01	8.59e-02
Downregulation of ERBB2 signaling	27	2.27e-01	3.66e-01	0.21100	-1.58e-01	1.40e-01	1.57e-01	2.08e-01
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	14	2.31e-01	3.73e-01	0.28100	-1.10e-01	2.58e-01	4.74e-01	9.46e-02
DAG and IP3 signaling	39	2.36e-01	3.81e-01	0.14000	8.19e-02	1.14e-01	3.76e-01	2.19e-01
Detoxification of Reactive Oxygen Species	33	2.37e-01	3.81e-01	0.18800	-1.28e-01	1.38e-01	2.03e-01	1.72e-01
Pre-NOTCH Expression and Processing	57	2.38e-01	3.81e-01	0.11700	5.84e-02	1.01e-01	4.46e-01	1.87e-01
Removal of the Flap Intermediate from the C-strand	16	2.38e-01	3.81e-01	0.23900	2.39e-01	-4.04e-04	9.74e-02	9.98e-01
Heparan sulfate/heparin (HS-GAG) metabolism	51	2.38e-01	3.81e-01	0.12300	-6.50e-02	-1.04e-01	4.22e-01	1.97e-01
CaM pathway	33	2.39e-01	3.82e-01	0.15200	8.37e-02	1.27e-01	4.05e-01	2.06e-01
Calmodulin induced events	33	2.39e-01	3.82e-01	0.15200	8.37e-02	1.27e-01	4.05e-01	2.06e-01
p75 NTR receptor-mediated signalling	95	2.41e-01	3.85e-01	0.10600	-3.66e-02	9.90e-02	5.38e-01	9.57e-02
NOTCH3 Intracellular Domain Regulates Transcription	24	2.43e-01	3.89e-01	0.18400	5.03e-02	1.77e-01	6.70e-01	1.34e-01
Thrombin signalling through proteinase activated receptors (PARs)	29	2.45e-01	3.91e-01	0.19000	-6.96e-02	1.77e-01	5.17e-01	9.90e-02
Golgi Cisternae Pericentriolar Stack Reorganization	13	2.45e-01	3.91e-01	0.28000	-8.23e-02	2.67e-01	6.08e-01	9.53e-02
Sphingolipid de novo biosynthesis	44	2.46e-01	3.92e-01	0.15400	-1.43e-01	5.67e-02	9.99e-02	5.15e-01
PIWI-interacting RNA (piRNA) biogenesis	22	2.47e-01	3.93e-01	0.19700	1.96e-01	2.02e-02	1.12e-01	8.70e-01
Mitochondrial calcium ion transport	22	2.48e-01	3.94e-01	0.20000	4.74e-03	2.00e-01	9.69e-01	1.05e-01
Free fatty acids regulate insulin secretion	10	2.48e-01	3.94e-01	0.33600	-2.40e-01	2.34e-01	1.88e-01	2.00e-01
G beta:gamma signalling through BTK	16	2.50e-01	3.96e-01	0.23800	-1.59e-02	2.38e-01	9.12e-01	9.96e-02
Glutathione conjugation	30	2.52e-01	3.97e-01	0.15600	1.20e-01	9.89e-02	2.54e-01	3.49e-01
Constitutive Signaling by NOTCH1 HD Domain Mutants	15	2.52e-01	3.97e-01	0.27000	-2.24e-01	1.52e-01	1.34e-01	3.10e-01
Signaling by NOTCH1 HD Domain Mutants in Cancer	15	2.52e-01	3.97e-01	0.27000	-2.24e-01	1.52e-01	1.34e-01	3.10e-01
Myogenesis	23	2.52e-01	3.98e-01	0.20000	-2.19e-02	1.99e-01	8.56e-01	9.88e-02
NOTCH2 intracellular domain regulates transcription	11	2.54e-01	3.99e-01	0.25600	1.94e-01	1.67e-01	2.64e-01	3.38e-01
VEGFR2 mediated cell proliferation	19	2.54e-01	3.99e-01	0.24200	-1.67e-01	1.74e-01	2.07e-01	1.88e-01
Insulin receptor recycling	24	2.54e-01	4.00e-01	0.18700	1.68e-02	1.86e-01	8.87e-01	1.14e-01
Phospholipid metabolism	195	2.57e-01	4.04e-01	0.06320	6.00e-02	1.97e-02	1.49e-01	6.35e-01
p38MAPK events	13	2.60e-01	4.07e-01	0.26500	-3.64e-02	2.62e-01	8.20e-01	1.02e-01
Dissolution of Fibrin Clot	12	2.60e-01	4.07e-01	0.26200	2.52e-02	2.61e-01	8.80e-01	1.18e-01
Notch-HLH transcription pathway	27	2.60e-01	4.07e-01	0.16300	1.38e-01	8.79e-02	2.16e-01	4.29e-01
ERK/MAPK targets	21	2.61e-01	4.08e-01	0.19800	1.72e-02	1.98e-01	8.92e-01	1.17e-01
Lysosome Vesicle Biogenesis	34	2.61e-01	4.08e-01	0.16700	-1.62e-01	3.93e-02	1.02e-01	6.92e-01
Translocation of ZAP-70 to Immunological synapse	13	2.62e-01	4.08e-01	0.24200	-2.31e-01	-7.21e-02	1.49e-01	6.53e-01
Protein localization	157	2.62e-01	4.08e-01	0.07210	9.33e-03	7.15e-02	8.40e-01	1.23e-01
Condensation of Prometaphase Chromosomes	11	2.64e-01	4.09e-01	0.25300	1.63e-01	1.93e-01	3.49e-01	2.68e-01
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	14	2.64e-01	4.09e-01	0.26800	-1.10e-01	2.45e-01	4.76e-01	1.13e-01
Downstream signaling of activated FGFR1	23	2.64e-01	4.09e-01	0.21100	-1.89e-01	9.32e-02	1.17e-01	4.39e-01
Activation of G protein gated Potassium channels	24	2.64e-01	4.09e-01	0.20100	-6.38e-02	1.91e-01	5.89e-01	1.06e-01
G protein gated Potassium channels	24	2.64e-01	4.09e-01	0.20100	-6.38e-02	1.91e-01	5.89e-01	1.06e-01
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	24	2.64e-01	4.09e-01	0.20100	-6.38e-02	1.91e-01	5.89e-01	1.06e-01
Initiation of Nuclear Envelope (NE) Reformation	19	2.65e-01	4.09e-01	0.20000	1.91e-01	5.89e-02	1.50e-01	6.57e-01
Condensation of Prophase Chromosomes	22	2.66e-01	4.11e-01	0.18100	1.63e-01	7.90e-02	1.85e-01	5.21e-01
COPI-dependent Golgi-to-ER retrograde traffic	79	2.68e-01	4.13e-01	0.11200	-1.04e-01	4.13e-02	1.11e-01	5.26e-01
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters	20	2.68e-01	4.13e-01	0.21300	-3.79e-02	2.10e-01	7.70e-01	1.05e-01
Aggrephagy	20	2.70e-01	4.16e-01	0.23000	-1.54e-01	1.70e-01	2.32e-01	1.88e-01
Pyrimidine catabolism	12	2.70e-01	4.16e-01	0.24100	2.01e-01	1.34e-01	2.29e-01	4.23e-01
Signaling by FGFR1 in disease	31	2.71e-01	4.16e-01	0.17100	-3.46e-02	1.68e-01	7.39e-01	1.06e-01
ROS and RNS production in phagocytes	35	2.76e-01	4.23e-01	0.16000	-3.02e-02	1.57e-01	7.58e-01	1.08e-01
Signaling by FGFR3 fusions in cancer	10	2.76e-01	4.23e-01	0.31400	-1.39e-01	2.82e-01	4.47e-01	1.23e-01
Signaling by FGFR2 in disease	34	2.77e-01	4.23e-01	0.14300	7.36e-02	1.22e-01	4.58e-01	2.18e-01
TRAF6-mediated induction of TAK1 complex within TLR4 complex	15	2.79e-01	4.27e-01	0.25100	-8.86e-02	2.35e-01	5.53e-01	1.15e-01
Signaling by Activin	12	2.80e-01	4.27e-01	0.26200	2.62e-01	-7.84e-03	1.17e-01	9.62e-01
Oncogene Induced Senescence	32	2.80e-01	4.27e-01	0.15600	1.56e-01	1.46e-02	1.28e-01	8.86e-01
Metal ion SLC transporters	24	2.80e-01	4.27e-01	0.20500	-1.68e-01	1.18e-01	1.54e-01	3.16e-01
Signaling by NODAL	16	2.84e-01	4.32e-01	0.22900	2.28e-01	-2.34e-02	1.15e-01	8.71e-01
Interleukin-2 signaling	11	2.84e-01	4.32e-01	0.25000	-2.23e-01	-1.13e-01	2.01e-01	5.18e-01
Formation of the Early Elongation Complex	33	2.90e-01	4.40e-01	0.14400	5.60e-02	1.33e-01	5.78e-01	1.87e-01
Formation of the HIV-1 Early Elongation Complex	33	2.90e-01	4.40e-01	0.14400	5.60e-02	1.33e-01	5.78e-01	1.87e-01
Synthesis of glycosylphosphatidylinositol (GPI)	17	2.91e-01	4.41e-01	0.21600	3.86e-03	-2.16e-01	9.78e-01	1.23e-01
MET activates PTK2 signaling	18	2.91e-01	4.41e-01	0.19900	5.01e-02	1.93e-01	7.13e-01	1.57e-01
Signaling by Insulin receptor	65	2.92e-01	4.41e-01	0.11800	-4.02e-02	1.11e-01	5.76e-01	1.21e-01
mitochondrial fatty acid beta-oxidation of saturated fatty acids	10	2.94e-01	4.43e-01	0.31400	-2.47e-01	1.94e-01	1.77e-01	2.89e-01
Methylation	12	2.94e-01	4.44e-01	0.26700	-2.61e-01	5.44e-02	1.18e-01	7.44e-01
Transferrin endocytosis and recycling	30	2.95e-01	4.45e-01	0.15100	5.05e-02	1.43e-01	6.32e-01	1.76e-01
Pregnenolone biosynthesis	11	2.96e-01	4.46e-01	0.25000	-7.74e-02	-2.38e-01	6.57e-01	1.71e-01
ADP signalling through P2Y purinoceptor 1	22	2.97e-01	4.47e-01	0.19300	-2.34e-02	1.91e-01	8.50e-01	1.21e-01
Glycosphingolipid metabolism	37	2.99e-01	4.49e-01	0.14400	-1.44e-01	-9.74e-04	1.30e-01	9.92e-01
Blood group systems biosynthesis	12	3.00e-01	4.49e-01	0.28400	-1.78e-01	2.21e-01	2.86e-01	1.84e-01
Lewis blood group biosynthesis	12	3.00e-01	4.49e-01	0.28400	-1.78e-01	2.21e-01	2.86e-01	1.84e-01
Retrograde neurotrophin signalling	14	3.00e-01	4.50e-01	0.25000	-7.51e-02	2.38e-01	6.27e-01	1.23e-01
TRAF6 mediated IRF7 activation	26	3.01e-01	4.51e-01	0.16700	-1.94e-02	-1.66e-01	8.64e-01	1.42e-01
p75NTR signals via NF-kB	16	3.02e-01	4.51e-01	0.24600	-1.62e-01	1.85e-01	2.62e-01	2.00e-01
TICAM1,TRAF6-dependent induction of TAK1 complex	11	3.03e-01	4.53e-01	0.27200	-4.33e-02	2.69e-01	8.04e-01	1.23e-01
Negative regulation of FGFR1 signaling	24	3.04e-01	4.54e-01	0.19700	-9.73e-02	1.71e-01	4.10e-01	1.47e-01
Nitric oxide stimulates guanylate cyclase	19	3.06e-01	4.55e-01	0.18100	1.35e-01	1.21e-01	3.09e-01	3.62e-01
Chromatin modifying enzymes	211	3.07e-01	4.55e-01	0.06690	-5.62e-02	3.64e-02	1.60e-01	3.63e-01
Chromatin organization	211	3.07e-01	4.55e-01	0.06690	-5.62e-02	3.64e-02	1.60e-01	3.63e-01
Gap junction trafficking and regulation	23	3.07e-01	4.55e-01	0.17600	2.56e-02	1.74e-01	8.32e-01	1.49e-01
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	21	3.07e-01	4.55e-01	0.20700	-1.87e-01	9.06e-02	1.39e-01	4.72e-01
Thromboxane signalling through TP receptor	21	3.07e-01	4.55e-01	0.20100	-5.59e-02	1.93e-01	6.58e-01	1.26e-01
AKT phosphorylates targets in the cytosol	14	3.08e-01	4.55e-01	0.22500	3.34e-02	2.22e-01	8.29e-01	1.50e-01
NOTCH2 Activation and Transmission of Signal to the Nucleus	22	3.09e-01	4.57e-01	0.18000	-1.79e-01	-2.19e-02	1.47e-01	8.59e-01
TRP channels	20	3.11e-01	4.59e-01	0.21700	1.59e-01	-1.48e-01	2.18e-01	2.52e-01
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways	48	3.11e-01	4.59e-01	0.13800	-7.00e-02	1.19e-01	4.02e-01	1.54e-01
Vpr-mediated nuclear import of PICs	34	3.11e-01	4.59e-01	0.13600	1.17e-01	6.86e-02	2.36e-01	4.89e-01
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression	25	3.12e-01	4.59e-01	0.19100	-9.56e-02	1.65e-01	4.08e-01	1.53e-01
Dopamine Neurotransmitter Release Cycle	20	3.12e-01	4.59e-01	0.21300	1.07e-01	-1.85e-01	4.09e-01	1.53e-01
FGFR2 mutant receptor activation	24	3.12e-01	4.59e-01	0.16700	1.60e-01	4.65e-02	1.75e-01	6.93e-01
Regulation of TP53 Activity through Acetylation	29	3.13e-01	4.59e-01	0.17200	-5.69e-02	1.62e-01	5.96e-01	1.31e-01
Adherens junctions interactions	25	3.13e-01	4.59e-01	0.19200	-1.06e-01	1.60e-01	3.58e-01	1.67e-01
Intraflagellar transport	40	3.13e-01	4.59e-01	0.13000	-1.25e-01	-3.26e-02	1.70e-01	7.21e-01
GRB2 events in EGFR signaling	10	3.13e-01	4.59e-01	0.29300	-1.03e-01	2.74e-01	5.71e-01	1.33e-01
Deadenylation-dependent mRNA decay	52	3.14e-01	4.59e-01	0.13300	-7.86e-02	1.08e-01	3.27e-01	1.79e-01
Regulation of IFNA signaling	24	3.16e-01	4.61e-01	0.17300	-1.19e-02	-1.72e-01	9.20e-01	1.44e-01
PKA-mediated phosphorylation of CREB	19	3.16e-01	4.62e-01	0.18100	8.34e-02	1.61e-01	5.29e-01	2.24e-01
Signaling by FGFR in disease	54	3.17e-01	4.62e-01	0.10600	6.75e-02	8.17e-02	3.91e-01	2.99e-01
Activation of NMDA receptors and postsynaptic events	73	3.18e-01	4.62e-01	0.09340	8.61e-02	3.63e-02	2.04e-01	5.92e-01
Signaling by ERBB2 ECD mutants	16	3.18e-01	4.62e-01	0.24100	-1.72e-01	1.68e-01	2.33e-01	2.44e-01
Carnitine metabolism	12	3.18e-01	4.62e-01	0.24300	2.43e-01	1.56e-02	1.45e-01	9.26e-01
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)	30	3.19e-01	4.62e-01	0.14900	1.45e-01	3.51e-02	1.71e-01	7.39e-01
Regulation of Glucokinase by Glucokinase Regulatory Protein	30	3.19e-01	4.62e-01	0.14900	1.45e-01	3.51e-02	1.71e-01	7.39e-01
SHC1 events in EGFR signaling	11	3.19e-01	4.62e-01	0.27600	-9.27e-02	2.60e-01	5.95e-01	1.35e-01
Ephrin signaling	18	3.19e-01	4.62e-01	0.18500	8.75e-02	1.63e-01	5.21e-01	2.30e-01
Gamma carboxylation, hypusine formation and arylsulfatase activation	34	3.20e-01	4.63e-01	0.13900	-3.66e-02	-1.34e-01	7.12e-01	1.77e-01
Netrin-1 signaling	46	3.20e-01	4.63e-01	0.13000	-1.97e-02	1.28e-01	8.17e-01	1.32e-01
Biosynthesis of specialized proresolving mediators (SPMs)	15	3.21e-01	4.63e-01	0.20800	6.02e-02	1.99e-01	6.87e-01	1.82e-01
Interconversion of nucleotide di- and triphosphates	27	3.23e-01	4.65e-01	0.16000	1.59e-01	1.79e-02	1.54e-01	8.72e-01
RHO GTPases activate CIT	19	3.24e-01	4.66e-01	0.18000	7.72e-02	1.63e-01	5.60e-01	2.19e-01
Signaling by ERBB2 in Cancer	24	3.26e-01	4.69e-01	0.19400	-1.29e-01	1.46e-01	2.76e-01	2.17e-01
Interferon alpha/beta signaling	59	3.27e-01	4.69e-01	0.10300	-3.99e-02	-9.45e-02	5.96e-01	2.10e-01
Alpha-protein kinase 1 signaling pathway	11	3.27e-01	4.69e-01	0.24500	4.76e-02	2.40e-01	7.85e-01	1.68e-01
Synthesis of PE	13	3.33e-01	4.77e-01	0.25500	2.27e-01	-1.17e-01	1.57e-01	4.65e-01
Signaling by NOTCH3	47	3.35e-01	4.79e-01	0.13000	-3.95e-02	1.24e-01	6.40e-01	1.41e-01
Negative regulation of FGFR4 signaling	23	3.36e-01	4.80e-01	0.19400	-1.04e-01	1.63e-01	3.87e-01	1.76e-01
SHC1 events in ERBB2 signaling	20	3.36e-01	4.80e-01	0.21000	-1.41e-01	1.55e-01	2.74e-01	2.29e-01
Reproduction	75	3.36e-01	4.80e-01	0.09610	9.61e-02	1.49e-03	1.50e-01	9.82e-01
Antigen Presentation: Folding, assembly and peptide loading of class I MHC	19	3.37e-01	4.81e-01	0.21400	-1.72e-01	1.28e-01	1.95e-01	3.35e-01
Degradation of cysteine and homocysteine	13	3.38e-01	4.82e-01	0.25900	1.99e-01	-1.65e-01	2.13e-01	3.02e-01
Processive synthesis on the lagging strand	14	3.40e-01	4.84e-01	0.24100	2.22e-01	-9.29e-02	1.50e-01	5.47e-01
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling	27	3.41e-01	4.85e-01	0.14800	6.02e-02	1.35e-01	5.88e-01	2.24e-01
Vitamin D (calciferol) metabolism	11	3.42e-01	4.86e-01	0.25400	2.53e-01	-1.97e-02	1.47e-01	9.10e-01
Stimuli-sensing channels	82	3.44e-01	4.88e-01	0.10200	8.33e-02	-5.90e-02	1.92e-01	3.56e-01
TRAF6 mediated NF-kB activation	21	3.45e-01	4.89e-01	0.17800	1.78e-01	8.33e-03	1.58e-01	9.47e-01
Transport of Ribonucleoproteins into the Host Nucleus	32	3.47e-01	4.92e-01	0.13200	1.03e-01	8.33e-02	3.15e-01	4.15e-01
RNA Polymerase I Transcription Initiation	44	3.49e-01	4.94e-01	0.13500	-1.23e-01	5.47e-02	1.58e-01	5.30e-01
Signaling by FGFR4 in disease	11	3.50e-01	4.94e-01	0.27800	-1.83e-01	2.09e-01	2.93e-01	2.31e-01
Regulation of beta-cell development	29	3.50e-01	4.94e-01	0.13800	1.10e-01	8.38e-02	3.04e-01	4.35e-01
NRIF signals cell death from the nucleus	16	3.51e-01	4.94e-01	0.23000	-1.45e-01	1.78e-01	3.16e-01	2.18e-01
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	43	3.51e-01	4.94e-01	0.13600	1.25e-01	-5.35e-02	1.57e-01	5.44e-01
VxPx cargo-targeting to cilium	18	3.53e-01	4.97e-01	0.19500	-1.95e-01	1.54e-02	1.53e-01	9.10e-01
HS-GAG degradation	21	3.55e-01	4.99e-01	0.16900	-1.64e-01	-4.12e-02	1.93e-01	7.44e-01
Signaling by FGFR2	63	3.55e-01	4.99e-01	0.10500	-9.48e-03	1.04e-01	8.96e-01	1.53e-01
Polo-like kinase mediated events	16	3.57e-01	5.01e-01	0.22300	1.98e-01	-1.01e-01	1.70e-01	4.84e-01
RNA Polymerase III Transcription Termination	21	3.58e-01	5.02e-01	0.18300	1.80e-01	-2.89e-02	1.53e-01	8.19e-01
Glyoxylate metabolism and glycine degradation	28	3.60e-01	5.04e-01	0.15600	1.55e-01	-1.82e-02	1.55e-01	8.68e-01
IRAK2 mediated activation of TAK1 complex	10	3.60e-01	5.04e-01	0.26500	-4.84e-02	2.61e-01	7.91e-01	1.53e-01
CRMPs in Sema3A signaling	16	3.61e-01	5.05e-01	0.22700	-1.48e-01	1.71e-01	3.05e-01	2.36e-01
Biosynthesis of DHA-derived SPMs	13	3.62e-01	5.05e-01	0.21000	6.86e-02	1.98e-01	6.69e-01	2.15e-01
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	32	3.63e-01	5.06e-01	0.14600	-1.87e-02	1.45e-01	8.55e-01	1.56e-01
Negative regulation of FGFR2 signaling	25	3.64e-01	5.08e-01	0.16400	-1.72e-02	1.63e-01	8.82e-01	1.58e-01
Biological oxidations	175	3.65e-01	5.08e-01	0.05910	5.85e-02	8.51e-03	1.83e-01	8.46e-01
TP53 Regulates Transcription of Caspase Activators and Caspases	11	3.67e-01	5.10e-01	0.22300	-2.00e-01	-9.94e-02	2.52e-01	5.68e-01
RNA Polymerase III Abortive And Retractive Initiation	39	3.68e-01	5.11e-01	0.13400	1.31e-01	-3.11e-02	1.58e-01	7.37e-01
RNA Polymerase III Transcription	39	3.68e-01	5.11e-01	0.13400	1.31e-01	-3.11e-02	1.58e-01	7.37e-01
activated TAK1 mediates p38 MAPK activation	17	3.69e-01	5.12e-01	0.17600	1.17e-01	1.31e-01	4.03e-01	3.50e-01
Phase 2 - plateau phase	12	3.70e-01	5.13e-01	0.25800	2.04e-01	-1.57e-01	2.21e-01	3.45e-01
Anchoring of the basal body to the plasma membrane	96	3.71e-01	5.14e-01	0.07410	5.89e-02	4.50e-02	3.19e-01	4.47e-01
RNA Polymerase I Promoter Clearance	56	3.72e-01	5.14e-01	0.11800	-5.97e-02	1.01e-01	4.40e-01	1.89e-01
RNA Polymerase I Transcription	56	3.72e-01	5.14e-01	0.11800	-5.97e-02	1.01e-01	4.40e-01	1.89e-01
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	13	3.76e-01	5.18e-01	0.21400	2.53e-02	2.12e-01	8.74e-01	1.85e-01
Peroxisomal protein import	61	3.76e-01	5.19e-01	0.11400	-8.67e-02	7.37e-02	2.42e-01	3.20e-01
Potassium Channels	83	3.80e-01	5.23e-01	0.08790	7.15e-03	-8.76e-02	9.10e-01	1.68e-01
Assembly Of The HIV Virion	16	3.83e-01	5.27e-01	0.18900	3.24e-02	1.86e-01	8.23e-01	1.98e-01
Aberrant regulation of mitotic exit in cancer due to RB1 defects	19	3.84e-01	5.27e-01	0.17100	1.65e-01	4.31e-02	2.13e-01	7.45e-01
Pre-NOTCH Processing in Golgi	17	3.85e-01	5.29e-01	0.19800	-4.21e-02	1.94e-01	7.64e-01	1.67e-01
Diseases of glycosylation	129	3.86e-01	5.29e-01	0.06280	5.06e-02	3.71e-02	3.21e-01	4.67e-01
SHC1 events in ERBB4 signaling	12	3.87e-01	5.31e-01	0.23200	-3.70e-02	2.29e-01	8.24e-01	1.69e-01
Regulation of PTEN gene transcription	60	3.92e-01	5.36e-01	0.11200	-6.41e-02	9.15e-02	3.91e-01	2.21e-01
Transcriptional regulation of white adipocyte differentiation	80	3.92e-01	5.36e-01	0.09520	-4.41e-02	8.44e-02	4.96e-01	1.92e-01
Caspase activation via Death Receptors in the presence of ligand	13	3.93e-01	5.36e-01	0.24100	-1.81e-01	1.59e-01	2.58e-01	3.22e-01
Disorders of Developmental Biology	13	3.94e-01	5.36e-01	0.23000	-7.95e-02	2.16e-01	6.20e-01	1.78e-01
Disorders of Nervous System Development	13	3.94e-01	5.36e-01	0.23000	-7.95e-02	2.16e-01	6.20e-01	1.78e-01
Loss of function of MECP2 in Rett syndrome	13	3.94e-01	5.36e-01	0.23000	-7.95e-02	2.16e-01	6.20e-01	1.78e-01
Pervasive developmental disorders	13	3.94e-01	5.36e-01	0.23000	-7.95e-02	2.16e-01	6.20e-01	1.78e-01
Gap junction trafficking	21	3.94e-01	5.36e-01	0.16300	2.53e-02	1.61e-01	8.41e-01	2.02e-01
Cytosolic sulfonation of small molecules	21	3.95e-01	5.37e-01	0.17000	9.25e-03	-1.70e-01	9.42e-01	1.78e-01
Signaling by Non-Receptor Tyrosine Kinases	52	3.97e-01	5.38e-01	0.10100	2.54e-02	9.83e-02	7.51e-01	2.21e-01
Signaling by PTK6	52	3.97e-01	5.38e-01	0.10100	2.54e-02	9.83e-02	7.51e-01	2.21e-01
Interleukin-27 signaling	10	4.01e-01	5.42e-01	0.27000	-1.57e-01	2.20e-01	3.91e-01	2.29e-01
Biotin transport and metabolism	11	4.01e-01	5.42e-01	0.21000	-1.73e-01	-1.20e-01	3.22e-01	4.91e-01
G beta:gamma signalling through PLC beta	18	4.01e-01	5.42e-01	0.18300	-1.54e-02	1.82e-01	9.10e-01	1.80e-01
Heme degradation	12	4.02e-01	5.42e-01	0.20100	1.09e-01	1.70e-01	5.14e-01	3.09e-01
Activation of the phototransduction cascade	10	4.02e-01	5.42e-01	0.24900	3.82e-02	-2.46e-01	8.34e-01	1.78e-01
Downregulation of ERBB2:ERBB3 signaling	13	4.02e-01	5.42e-01	0.23400	-1.16e-01	2.03e-01	4.69e-01	2.05e-01
Cell death signalling via NRAGE, NRIF and NADE	74	4.03e-01	5.42e-01	0.09480	-2.97e-02	9.01e-02	6.59e-01	1.81e-01
RET signaling	40	4.05e-01	5.45e-01	0.12200	-1.21e-01	6.82e-03	1.84e-01	9.41e-01
Class B/2 (Secretin family receptors)	61	4.06e-01	5.46e-01	0.09810	-4.46e-03	9.80e-02	9.52e-01	1.86e-01
tRNA processing	121	4.10e-01	5.50e-01	0.06370	2.82e-02	5.71e-02	5.93e-01	2.79e-01
Phase II - Conjugation of compounds	85	4.10e-01	5.50e-01	0.09220	5.98e-02	-7.02e-02	3.41e-01	2.64e-01
Zinc influx into cells by the SLC39 gene family	10	4.10e-01	5.50e-01	0.22000	-1.96e-01	-1.00e-01	2.83e-01	5.83e-01
Synthesis of substrates in N-glycan biosythesis	58	4.12e-01	5.52e-01	0.10300	-1.01e-01	2.19e-02	1.83e-01	7.73e-01
Triglyceride biosynthesis	12	4.14e-01	5.54e-01	0.24400	1.82e-01	-1.62e-01	2.76e-01	3.30e-01
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)	94	4.14e-01	5.54e-01	0.07270	6.83e-02	2.49e-02	2.53e-01	6.77e-01
Class I peroxisomal membrane protein import	20	4.17e-01	5.57e-01	0.15500	1.42e-01	6.26e-02	2.71e-01	6.28e-01
Regulation of cholesterol biosynthesis by SREBP (SREBF)	55	4.19e-01	5.59e-01	0.11200	-9.18e-02	6.48e-02	2.39e-01	4.06e-01
Termination of O-glycan biosynthesis	16	4.22e-01	5.62e-01	0.17900	1.77e-01	2.91e-02	2.20e-01	8.40e-01
Transmission across Chemical Synapses	212	4.24e-01	5.64e-01	0.05640	4.96e-02	-2.69e-02	2.14e-01	5.01e-01
Transcriptional Regulation by MECP2	52	4.26e-01	5.66e-01	0.11500	-6.62e-02	9.34e-02	4.09e-01	2.44e-01
Processing of SMDT1	15	4.28e-01	5.67e-01	0.19500	-2.35e-02	1.94e-01	8.75e-01	1.94e-01
Phase 4 - resting membrane potential	11	4.28e-01	5.67e-01	0.21300	-2.10e-01	-4.07e-02	2.29e-01	8.15e-01
Activation of SMO	17	4.28e-01	5.67e-01	0.16200	-1.25e-01	-1.04e-01	3.73e-01	4.59e-01
Signaling by cytosolic FGFR1 fusion mutants	18	4.28e-01	5.67e-01	0.18300	-4.44e-02	1.77e-01	7.45e-01	1.93e-01
PI-3K cascade:FGFR4	12	4.29e-01	5.67e-01	0.21600	-2.15e-01	1.93e-02	1.97e-01	9.08e-01
PKA activation	17	4.29e-01	5.67e-01	0.16300	1.32e-01	9.45e-02	3.45e-01	5.00e-01
Dermatan sulfate biosynthesis	11	4.30e-01	5.68e-01	0.20200	1.67e-01	1.14e-01	3.38e-01	5.13e-01
TBC/RABGAPs	43	4.30e-01	5.68e-01	0.10300	8.96e-02	5.07e-02	3.09e-01	5.65e-01
TNFs bind their physiological receptors	20	4.31e-01	5.69e-01	0.17900	1.62e-01	-7.70e-02	2.11e-01	5.51e-01
NF-kB is activated and signals survival	13	4.33e-01	5.70e-01	0.22800	-1.73e-01	1.48e-01	2.80e-01	3.55e-01
Aflatoxin activation and detoxification	14	4.37e-01	5.75e-01	0.18600	-4.11e-02	-1.81e-01	7.90e-01	2.40e-01
Metabolism of fat-soluble vitamins	43	4.39e-01	5.77e-01	0.11000	5.47e-04	1.10e-01	9.95e-01	2.11e-01
Retinoid metabolism and transport	39	4.39e-01	5.77e-01	0.10700	4.70e-02	9.66e-02	6.12e-01	2.97e-01
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	13	4.40e-01	5.78e-01	0.22000	-1.98e-01	9.57e-02	2.17e-01	5.50e-01
Transcriptional Regulation by VENTX	35	4.41e-01	5.78e-01	0.13800	9.95e-02	-9.52e-02	3.09e-01	3.30e-01
Glucagon signaling in metabolic regulation	28	4.42e-01	5.79e-01	0.12500	6.70e-02	1.05e-01	5.40e-01	3.34e-01
Removal of the Flap Intermediate	13	4.44e-01	5.82e-01	0.21900	1.95e-01	-9.87e-02	2.22e-01	5.38e-01
Fanconi Anemia Pathway	35	4.46e-01	5.83e-01	0.12900	1.24e-01	-3.52e-02	2.05e-01	7.19e-01
Negative regulation of FGFR3 signaling	23	4.49e-01	5.87e-01	0.15600	-3.45e-02	1.52e-01	7.74e-01	2.06e-01
Kinesins	40	4.50e-01	5.87e-01	0.12700	8.56e-02	-9.40e-02	3.49e-01	3.04e-01
Organelle biogenesis and maintenance	271	4.51e-01	5.87e-01	0.04430	-3.14e-03	4.42e-02	9.29e-01	2.12e-01
Ketone body metabolism	10	4.51e-01	5.87e-01	0.25100	-2.08e-01	1.41e-01	2.55e-01	4.40e-01
Cell recruitment (pro-inflammatory response)	22	4.51e-01	5.87e-01	0.14100	5.51e-02	1.30e-01	6.55e-01	2.90e-01
Purinergic signaling in leishmaniasis infection	22	4.51e-01	5.87e-01	0.14100	5.51e-02	1.30e-01	6.55e-01	2.90e-01
PINK1-PRKN Mediated Mitophagy	20	4.52e-01	5.87e-01	0.17900	-1.14e-01	1.38e-01	3.77e-01	2.86e-01
Hyaluronan metabolism	16	4.52e-01	5.87e-01	0.20000	1.36e-01	-1.47e-01	3.47e-01	3.08e-01
Energy dependent regulation of mTOR by LKB1-AMPK	29	4.53e-01	5.87e-01	0.14800	1.18e-01	-9.01e-02	2.73e-01	4.01e-01
B-WICH complex positively regulates rRNA expression	37	4.53e-01	5.87e-01	0.11800	-4.38e-03	1.18e-01	9.63e-01	2.15e-01
Dectin-2 family	18	4.53e-01	5.87e-01	0.16500	-1.65e-01	-1.02e-02	2.26e-01	9.40e-01
Transport of Mature Transcript to Cytoplasm	80	4.54e-01	5.87e-01	0.08900	-7.20e-02	5.23e-02	2.66e-01	4.19e-01
Purine ribonucleoside monophosphate biosynthesis	10	4.55e-01	5.88e-01	0.20600	9.95e-02	1.81e-01	5.86e-01	3.23e-01
Depolymerisation of the Nuclear Lamina	15	4.55e-01	5.88e-01	0.17700	1.75e-01	2.82e-02	2.41e-01	8.50e-01
O-linked glycosylation	97	4.57e-01	5.89e-01	0.07120	7.11e-02	3.35e-03	2.26e-01	9.55e-01
Nuclear Receptor transcription pathway	50	4.59e-01	5.92e-01	0.09500	-9.21e-02	-2.33e-02	2.60e-01	7.76e-01
VLDLR internalisation and degradation	12	4.61e-01	5.93e-01	0.22500	-1.94e-01	1.12e-01	2.44e-01	5.00e-01
Signaling by NTRK3 (TRKC)	17	4.61e-01	5.93e-01	0.16500	1.62e-01	2.81e-02	2.47e-01	8.41e-01
Translation of Replicase and Assembly of the Replication Transcription Complex	11	4.61e-01	5.93e-01	0.19200	1.37e-01	1.35e-01	4.32e-01	4.38e-01
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA	16	4.62e-01	5.93e-01	0.17100	2.18e-02	1.69e-01	8.80e-01	2.41e-01
ZBP1(DAI) mediated induction of type I IFNs	21	4.64e-01	5.95e-01	0.17200	-1.20e-01	1.23e-01	3.39e-01	3.30e-01
Collagen biosynthesis and modifying enzymes	56	4.65e-01	5.95e-01	0.10500	-6.21e-02	8.43e-02	4.22e-01	2.75e-01
Caspase activation via extrinsic apoptotic signalling pathway	22	4.66e-01	5.95e-01	0.16700	-1.23e-01	1.14e-01	3.19e-01	3.56e-01
RNA Polymerase III Transcription Initiation	34	4.67e-01	5.95e-01	0.12800	1.22e-01	-3.78e-02	2.19e-01	7.03e-01
Homology Directed Repair	100	4.67e-01	5.95e-01	0.06550	6.14e-02	2.29e-02	2.89e-01	6.93e-01
Regulation of FZD by ubiquitination	18	4.67e-01	5.95e-01	0.15700	1.52e-01	3.73e-02	2.64e-01	7.84e-01
Ras activation upon Ca2+ influx through NMDA receptor	19	4.67e-01	5.95e-01	0.15300	1.49e-01	3.35e-02	2.60e-01	8.00e-01
Activated NTRK2 signals through FRS2 and FRS3	11	4.68e-01	5.95e-01	0.23000	-1.04e-01	2.06e-01	5.51e-01	2.38e-01
Assembly and cell surface presentation of NMDA receptors	24	4.68e-01	5.95e-01	0.16000	1.20e-01	-1.05e-01	3.09e-01	3.71e-01
RNA Polymerase III Transcription Initiation From Type 3 Promoter	26	4.68e-01	5.95e-01	0.13600	1.36e-01	2.83e-03	2.31e-01	9.80e-01
Metabolism of Angiotensinogen to Angiotensins	13	4.69e-01	5.95e-01	0.20000	1.97e-01	-3.22e-02	2.19e-01	8.41e-01
Negative epigenetic regulation of rRNA expression	55	4.69e-01	5.95e-01	0.09190	9.16e-03	9.14e-02	9.07e-01	2.41e-01
FGFR1 mutant receptor activation	24	4.70e-01	5.96e-01	0.14500	-1.71e-02	1.44e-01	8.85e-01	2.21e-01
NCAM signaling for neurite out-growth	53	4.70e-01	5.96e-01	0.08770	4.38e-02	7.60e-02	5.82e-01	3.39e-01
Regulation of RUNX1 Expression and Activity	17	4.71e-01	5.96e-01	0.15900	-4.37e-02	-1.53e-01	7.55e-01	2.74e-01
RA biosynthesis pathway	19	4.71e-01	5.96e-01	0.15800	-1.58e-01	-2.11e-03	2.32e-01	9.87e-01
RNA Polymerase III Chain Elongation	16	4.73e-01	5.97e-01	0.18200	1.77e-01	-4.25e-02	2.21e-01	7.68e-01
Neurexins and neuroligins	52	4.76e-01	6.02e-01	0.10100	2.41e-02	-9.76e-02	7.64e-01	2.24e-01
Nucleobase biosynthesis	13	4.77e-01	6.02e-01	0.18400	1.81e-01	3.18e-02	2.58e-01	8.43e-01
Deactivation of the beta-catenin transactivating complex	39	4.80e-01	6.05e-01	0.11500	-1.12e-01	2.48e-02	2.26e-01	7.89e-01
PI-3K cascade:FGFR1	13	4.81e-01	6.05e-01	0.19900	-1.94e-01	4.46e-02	2.26e-01	7.81e-01
Collagen chain trimerization	34	4.81e-01	6.05e-01	0.13200	-9.96e-02	8.64e-02	3.15e-01	3.83e-01
Signaling by ERBB2 KD Mutants	23	4.82e-01	6.06e-01	0.16000	-1.16e-01	1.11e-01	3.35e-01	3.59e-01
DNA Double-Strand Break Repair	128	4.82e-01	6.06e-01	0.05590	4.97e-02	2.55e-02	3.32e-01	6.19e-01
Nonhomologous End-Joining (NHEJ)	35	4.84e-01	6.06e-01	0.12100	-1.18e-01	2.79e-02	2.28e-01	7.75e-01
Telomere C-strand synthesis initiation	13	4.84e-01	6.06e-01	0.20200	6.47e-02	-1.91e-01	6.86e-01	2.32e-01
WNT5A-dependent internalization of FZD4	15	4.84e-01	6.06e-01	0.18300	-3.68e-02	1.80e-01	8.05e-01	2.28e-01
Synthesis, secretion, and deacylation of Ghrelin	13	4.87e-01	6.09e-01	0.21100	-1.60e-01	1.39e-01	3.19e-01	3.87e-01
FOXO-mediated transcription of cell death genes	15	4.87e-01	6.09e-01	0.18000	2.45e-02	-1.78e-01	8.69e-01	2.32e-01
PPARA activates gene expression	114	4.87e-01	6.09e-01	0.07150	-4.65e-02	5.44e-02	3.92e-01	3.17e-01
Postmitotic nuclear pore complex (NPC) reformation	27	4.90e-01	6.12e-01	0.13200	-1.18e-02	1.32e-01	9.15e-01	2.36e-01
Synthesis of PA	32	4.91e-01	6.12e-01	0.13400	9.78e-02	-9.19e-02	3.39e-01	3.69e-01
Mucopolysaccharidoses	11	4.91e-01	6.12e-01	0.20500	-2.05e-01	8.86e-03	2.40e-01	9.59e-01
Signaling by FGFR	74	4.92e-01	6.12e-01	0.08700	-4.58e-02	7.39e-02	4.96e-01	2.72e-01
Synthesis of PC	27	4.92e-01	6.12e-01	0.13100	-5.33e-03	1.30e-01	9.62e-01	2.41e-01
Chylomicron assembly	10	4.95e-01	6.15e-01	0.19200	1.44e-01	1.28e-01	4.31e-01	4.84e-01
ERKs are inactivated	12	4.97e-01	6.17e-01	0.19700	-1.75e-02	1.96e-01	9.16e-01	2.40e-01
Cobalamin (Cbl, vitamin B12) transport and metabolism	16	4.97e-01	6.17e-01	0.15200	-8.95e-02	-1.23e-01	5.35e-01	3.94e-01
Platelet Adhesion to exposed collagen	12	4.99e-01	6.18e-01	0.21100	-1.89e-01	9.31e-02	2.57e-01	5.76e-01
RIPK1-mediated regulated necrosis	26	5.02e-01	6.21e-01	0.13600	-2.98e-02	1.33e-01	7.92e-01	2.40e-01
Regulated Necrosis	26	5.02e-01	6.21e-01	0.13600	-2.98e-02	1.33e-01	7.92e-01	2.40e-01
Regulation of necroptotic cell death	26	5.02e-01	6.21e-01	0.13600	-2.98e-02	1.33e-01	7.92e-01	2.40e-01
Glutamate Neurotransmitter Release Cycle	19	5.03e-01	6.21e-01	0.16800	8.45e-02	-1.45e-01	5.24e-01	2.73e-01
AKT phosphorylates targets in the nucleus	10	5.04e-01	6.22e-01	0.19300	8.58e-02	1.73e-01	6.38e-01	3.43e-01
NEP/NS2 Interacts with the Cellular Export Machinery	32	5.04e-01	6.22e-01	0.10700	8.81e-02	6.03e-02	3.88e-01	5.55e-01
Inflammasomes	20	5.05e-01	6.22e-01	0.15200	-1.51e-01	2.14e-02	2.44e-01	8.68e-01
FGFR2 ligand binding and activation	10	5.05e-01	6.22e-01	0.23200	1.94e-01	-1.28e-01	2.88e-01	4.83e-01
mRNA decay by 5' to 3' exoribonuclease	15	5.07e-01	6.22e-01	0.16100	4.77e-02	1.53e-01	7.49e-01	3.04e-01
SUMOylation of chromatin organization proteins	56	5.07e-01	6.22e-01	0.08920	-5.40e-03	8.91e-02	9.44e-01	2.49e-01
Synthesis of IP3 and IP4 in the cytosol	25	5.07e-01	6.22e-01	0.13400	-1.30e-02	1.34e-01	9.11e-01	2.47e-01
Unblocking of NMDA receptors, glutamate binding and activation	20	5.09e-01	6.25e-01	0.16400	1.35e-01	-9.20e-02	2.95e-01	4.76e-01
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation	10	5.11e-01	6.26e-01	0.22400	-2.08e-01	8.36e-02	2.55e-01	6.47e-01
ERBB2 Activates PTK6 Signaling	11	5.13e-01	6.27e-01	0.17900	-1.15e-01	-1.37e-01	5.09e-01	4.31e-01
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	16	5.13e-01	6.27e-01	0.18400	-1.30e-01	1.30e-01	3.68e-01	3.69e-01
Mitochondrial iron-sulfur cluster biogenesis	11	5.14e-01	6.28e-01	0.19000	1.87e-01	3.25e-02	2.83e-01	8.52e-01
SUMOylation of RNA binding proteins	47	5.15e-01	6.29e-01	0.08780	3.99e-02	7.82e-02	6.36e-01	3.54e-01
cGMP effects	15	5.20e-01	6.34e-01	0.15200	1.22e-01	9.02e-02	4.12e-01	5.45e-01
SHC-mediated cascade:FGFR2	14	5.28e-01	6.43e-01	0.15500	1.18e-01	1.00e-01	4.43e-01	5.16e-01
tRNA processing in the nucleus	59	5.28e-01	6.43e-01	0.07800	2.65e-02	7.34e-02	7.25e-01	3.30e-01
G1/S-Specific Transcription	28	5.31e-01	6.46e-01	0.11700	1.54e-02	1.16e-01	8.88e-01	2.89e-01
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	14	5.32e-01	6.46e-01	0.18900	-1.58e-01	1.03e-01	3.05e-01	5.05e-01
Defective EXT1 causes exostoses 1, TRPS2 and CHDS	14	5.32e-01	6.46e-01	0.17100	-4.76e-03	1.70e-01	9.75e-01	2.69e-01
Defective EXT2 causes exostoses 2	14	5.32e-01	6.46e-01	0.17100	-4.76e-03	1.70e-01	9.75e-01	2.69e-01
Selective autophagy	57	5.35e-01	6.48e-01	0.08590	-1.04e-02	8.53e-02	8.92e-01	2.66e-01
Transcriptional activation of mitochondrial biogenesis	52	5.35e-01	6.48e-01	0.09870	-7.31e-02	6.63e-02	3.62e-01	4.09e-01
DNA methylation	13	5.35e-01	6.48e-01	0.17000	1.69e-01	2.21e-02	2.91e-01	8.90e-01
RAS processing	19	5.37e-01	6.49e-01	0.15500	-5.30e-02	1.46e-01	6.89e-01	2.70e-01
Phosphorylation of the APC/C	19	5.37e-01	6.49e-01	0.13400	1.21e-01	5.70e-02	3.61e-01	6.67e-01
Meiotic synapsis	34	5.38e-01	6.50e-01	0.09870	5.28e-02	8.34e-02	5.94e-01	4.00e-01
Amine ligand-binding receptors	16	5.40e-01	6.51e-01	0.15600	-4.18e-03	-1.56e-01	9.77e-01	2.81e-01
Export of Viral Ribonucleoproteins from Nucleus	33	5.41e-01	6.53e-01	0.09960	5.54e-02	8.28e-02	5.82e-01	4.11e-01
APC/C:Cdc20 mediated degradation of Cyclin B	23	5.48e-01	6.59e-01	0.11700	8.90e-02	7.66e-02	4.60e-01	5.25e-01
Acyl chain remodelling of PE	20	5.48e-01	6.59e-01	0.14500	1.42e-01	-3.04e-02	2.73e-01	8.14e-01
Sulfur amino acid metabolism	26	5.50e-01	6.61e-01	0.13500	7.64e-02	-1.12e-01	5.00e-01	3.25e-01
HDR through MMEJ (alt-NHEJ)	10	5.50e-01	6.61e-01	0.20900	-6.67e-02	1.98e-01	7.15e-01	2.78e-01
TRAF3-dependent IRF activation pathway	12	5.51e-01	6.62e-01	0.17300	-1.72e-01	-2.23e-02	3.03e-01	8.94e-01
Metabolism of folate and pterines	17	5.52e-01	6.62e-01	0.16000	1.51e-01	-5.26e-02	2.80e-01	7.07e-01
Inactivation of APC/C via direct inhibition of the APC/C complex	20	5.53e-01	6.62e-01	0.12800	1.18e-01	4.89e-02	3.59e-01	7.05e-01
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components	20	5.53e-01	6.62e-01	0.12800	1.18e-01	4.89e-02	3.59e-01	7.05e-01
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)	26	5.58e-01	6.67e-01	0.12300	1.22e-01	-1.46e-02	2.82e-01	8.97e-01
MicroRNA (miRNA) biogenesis	24	5.58e-01	6.67e-01	0.13600	1.23e-01	-5.99e-02	2.98e-01	6.12e-01
Activation of Matrix Metalloproteinases	22	5.58e-01	6.67e-01	0.14300	-1.27e-01	6.54e-02	3.02e-01	5.95e-01
Peptide hormone metabolism	64	5.61e-01	6.70e-01	0.08420	-4.27e-02	7.25e-02	5.55e-01	3.16e-01
Growth hormone receptor signaling	20	5.63e-01	6.72e-01	0.12800	1.23e-01	3.67e-02	3.43e-01	7.76e-01
Regulation of lipid metabolism by PPARalpha	116	5.64e-01	6.72e-01	0.06260	-3.39e-02	5.26e-02	5.29e-01	3.28e-01
Signaling by Retinoic Acid	38	5.67e-01	6.74e-01	0.10300	-2.40e-02	9.99e-02	7.98e-01	2.87e-01
Erythrocytes take up carbon dioxide and release oxygen	10	5.67e-01	6.74e-01	0.17500	1.53e-01	8.57e-02	4.04e-01	6.39e-01
O2/CO2 exchange in erythrocytes	10	5.67e-01	6.74e-01	0.17500	1.53e-01	8.57e-02	4.04e-01	6.39e-01
Interleukin-6 family signaling	21	5.67e-01	6.74e-01	0.12700	2.20e-02	1.25e-01	8.61e-01	3.23e-01
LDL clearance	19	5.68e-01	6.74e-01	0.14600	-4.03e-02	1.41e-01	7.61e-01	2.89e-01
Signaling by NTRK2 (TRKB)	25	5.69e-01	6.74e-01	0.13200	-6.37e-02	1.16e-01	5.81e-01	3.15e-01
PKA activation in glucagon signalling	16	5.69e-01	6.74e-01	0.13800	1.20e-01	6.82e-02	4.07e-01	6.37e-01
Processing of DNA double-strand break ends	62	5.70e-01	6.74e-01	0.06930	4.32e-02	5.42e-02	5.56e-01	4.61e-01
Post-translational modification: synthesis of GPI-anchored proteins	76	5.70e-01	6.74e-01	0.07670	4.26e-02	-6.38e-02	5.21e-01	3.37e-01
Synthesis of PIPs at the Golgi membrane	18	5.73e-01	6.77e-01	0.15300	-1.40e-01	5.98e-02	3.02e-01	6.61e-01
RIP-mediated NFkB activation via ZBP1	17	5.79e-01	6.83e-01	0.15800	-7.65e-02	1.38e-01	5.85e-01	3.24e-01
Diseases associated with visual transduction	10	5.81e-01	6.84e-01	0.17000	-1.37e-01	-1.00e-01	4.53e-01	5.84e-01
Diseases of the neuronal system	10	5.81e-01	6.84e-01	0.17000	-1.37e-01	-1.00e-01	4.53e-01	5.84e-01
Retinoid cycle disease events	10	5.81e-01	6.84e-01	0.17000	-1.37e-01	-1.00e-01	4.53e-01	5.84e-01
Interleukin-20 family signaling	16	5.84e-01	6.87e-01	0.16300	8.93e-02	-1.37e-01	5.36e-01	3.44e-01
Presynaptic function of Kainate receptors	19	5.84e-01	6.87e-01	0.13700	-1.29e-02	1.36e-01	9.22e-01	3.03e-01
RNA Polymerase III Transcription Initiation From Type 1 Promoter	26	5.86e-01	6.88e-01	0.12500	1.13e-01	-5.31e-02	3.18e-01	6.39e-01
Synthesis of PIPs at the late endosome membrane	11	5.86e-01	6.88e-01	0.19100	-1.76e-01	7.34e-02	3.12e-01	6.73e-01
Plasma lipoprotein assembly	17	5.87e-01	6.88e-01	0.15300	1.42e-01	-5.90e-02	3.12e-01	6.74e-01
RNA Polymerase III Transcription Initiation From Type 2 Promoter	25	5.87e-01	6.88e-01	0.12700	1.16e-01	-5.09e-02	3.15e-01	6.60e-01
Downstream signaling of activated FGFR4	19	5.88e-01	6.88e-01	0.14700	-1.30e-01	6.87e-02	3.27e-01	6.04e-01
Factors involved in megakaryocyte development and platelet production	126	5.89e-01	6.88e-01	0.04820	2.05e-02	4.36e-02	6.91e-01	3.99e-01
MAP3K8 (TPL2)-dependent MAPK1/3 activation	16	5.93e-01	6.93e-01	0.14700	-1.21e-02	1.46e-01	9.33e-01	3.11e-01
Nuclear import of Rev protein	33	5.95e-01	6.94e-01	0.09490	9.09e-02	2.73e-02	3.66e-01	7.86e-01
Transport of Mature mRNA derived from an Intron-Containing Transcript	72	5.98e-01	6.97e-01	0.07580	-5.97e-02	4.67e-02	3.81e-01	4.93e-01
Ethanol oxidation	11	6.01e-01	7.00e-01	0.19000	-9.50e-02	1.65e-01	5.85e-01	3.44e-01
Metabolism of cofactors	19	6.02e-01	7.00e-01	0.14100	-1.32e-01	4.86e-02	3.20e-01	7.14e-01
Regulation of TP53 Activity through Association with Co-factors	13	6.02e-01	7.00e-01	0.14500	1.24e-01	7.41e-02	4.38e-01	6.44e-01
PI3K events in ERBB2 signaling	14	6.03e-01	7.00e-01	0.14500	-1.40e-01	-3.60e-02	3.64e-01	8.15e-01
Activation of kainate receptors upon glutamate binding	27	6.03e-01	7.00e-01	0.09930	6.61e-02	7.42e-02	5.53e-01	5.05e-01
Tight junction interactions	24	6.04e-01	7.00e-01	0.12900	6.97e-02	-1.09e-01	5.55e-01	3.58e-01
Glutamate binding, activation of AMPA receptors and synaptic plasticity	28	6.07e-01	7.03e-01	0.10900	1.09e-01	-1.15e-02	3.20e-01	9.16e-01
Trafficking of AMPA receptors	28	6.07e-01	7.03e-01	0.10900	1.09e-01	-1.15e-02	3.20e-01	9.16e-01
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA	16	6.08e-01	7.04e-01	0.14100	-1.32e-03	1.41e-01	9.93e-01	3.29e-01
Defects in cobalamin (B12) metabolism	13	6.09e-01	7.04e-01	0.14400	-1.28e-01	-6.66e-02	4.26e-01	6.78e-01
FRS-mediated FGFR1 signaling	15	6.14e-01	7.10e-01	0.16200	-1.14e-01	1.15e-01	4.45e-01	4.39e-01
Interleukin-7 signaling	22	6.14e-01	7.10e-01	0.12000	1.20e-01	-7.40e-03	3.29e-01	9.52e-01
Neurotransmitter receptors and postsynaptic signal transmission	160	6.17e-01	7.12e-01	0.04160	3.97e-02	1.25e-02	3.87e-01	7.85e-01
SUMOylation of transcription factors	17	6.18e-01	7.13e-01	0.12300	6.09e-02	1.07e-01	6.64e-01	4.43e-01
Nucleobase catabolism	36	6.20e-01	7.14e-01	0.09700	9.42e-02	-2.31e-02	3.28e-01	8.11e-01
Negative regulation of NMDA receptor-mediated neuronal transmission	20	6.21e-01	7.15e-01	0.13700	7.29e-02	-1.16e-01	5.73e-01	3.69e-01
Collagen degradation	30	6.24e-01	7.18e-01	0.11300	-7.29e-02	8.58e-02	4.89e-01	4.16e-01
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase	19	6.25e-01	7.18e-01	0.11900	1.14e-01	3.38e-02	3.90e-01	7.99e-01
Competing endogenous RNAs (ceRNAs) regulate PTEN translation	10	6.26e-01	7.19e-01	0.18200	4.23e-02	-1.77e-01	8.17e-01	3.33e-01
The NLRP3 inflammasome	15	6.26e-01	7.19e-01	0.15600	-8.06e-02	1.34e-01	5.89e-01	3.69e-01
SUMOylation of DNA methylation proteins	16	6.27e-01	7.19e-01	0.12600	-5.63e-02	-1.13e-01	6.97e-01	4.35e-01
SUMOylation of immune response proteins	11	6.30e-01	7.21e-01	0.17900	1.61e-01	-7.79e-02	3.54e-01	6.55e-01
NoRC negatively regulates rRNA expression	52	6.30e-01	7.21e-01	0.07510	1.15e-03	7.51e-02	9.89e-01	3.49e-01
NOTCH3 Activation and Transmission of Signal to the Nucleus	24	6.32e-01	7.23e-01	0.12300	-1.02e-01	6.90e-02	3.87e-01	5.59e-01
Nicotinamide salvaging	18	6.33e-01	7.24e-01	0.11600	7.66e-02	8.66e-02	5.74e-01	5.25e-01
Antimicrobial peptides	23	6.38e-01	7.27e-01	0.12600	-9.05e-02	8.74e-02	4.53e-01	4.68e-01
FRS-mediated FGFR4 signaling	14	6.38e-01	7.27e-01	0.16100	-1.27e-01	9.88e-02	4.12e-01	5.22e-01
Cilium Assembly	182	6.38e-01	7.27e-01	0.04150	-4.08e-02	7.66e-03	3.43e-01	8.59e-01
Beta-oxidation of very long chain fatty acids	11	6.40e-01	7.29e-01	0.18100	1.22e-01	-1.34e-01	4.84e-01	4.43e-01
IRS-related events triggered by IGF1R	40	6.42e-01	7.31e-01	0.09320	-8.00e-02	4.77e-02	3.81e-01	6.02e-01
IGF1R signaling cascade	41	6.44e-01	7.32e-01	0.09220	-7.78e-02	4.95e-02	3.89e-01	5.84e-01
The canonical retinoid cycle in rods (twilight vision)	17	6.45e-01	7.33e-01	0.11700	-6.88e-02	-9.45e-02	6.23e-01	5.00e-01
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol	17	6.46e-01	7.33e-01	0.12000	4.18e-02	1.13e-01	7.65e-01	4.22e-01
Platelet Aggregation (Plug Formation)	36	6.50e-01	7.38e-01	0.08030	4.01e-02	6.96e-02	6.77e-01	4.70e-01
Regulation of MECP2 expression and activity	29	6.56e-01	7.44e-01	0.10200	-9.82e-02	2.72e-02	3.60e-01	8.00e-01
Nuclear signaling by ERBB4	28	6.61e-01	7.49e-01	0.09810	-4.60e-03	9.80e-02	9.66e-01	3.70e-01
Defective B3GALT6 causes EDSP2 and SEMDJL1	20	6.65e-01	7.52e-01	0.10700	3.48e-02	1.02e-01	7.88e-01	4.32e-01
Insulin receptor signalling cascade	42	6.65e-01	7.52e-01	0.08870	-6.26e-02	6.28e-02	4.83e-01	4.81e-01
Regulation of TNFR1 signaling	35	6.66e-01	7.53e-01	0.09640	-7.74e-02	5.75e-02	4.29e-01	5.56e-01
mTORC1-mediated signalling	24	6.69e-01	7.55e-01	0.10800	-1.06e-01	2.36e-02	3.70e-01	8.41e-01
Regulation of gene expression in beta cells	13	6.73e-01	7.59e-01	0.13300	1.28e-01	3.38e-02	4.24e-01	8.33e-01
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	42	6.74e-01	7.59e-01	0.08700	-6.77e-02	5.47e-02	4.48e-01	5.40e-01
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1	16	6.75e-01	7.60e-01	0.11600	5.13e-02	1.04e-01	7.22e-01	4.72e-01
Effects of PIP2 hydrolysis	25	6.75e-01	7.60e-01	0.09480	-2.67e-02	-9.10e-02	8.17e-01	4.31e-01
DDX58/IFIH1-mediated induction of interferon-alpha/beta	71	6.76e-01	7.60e-01	0.06660	-4.03e-02	5.30e-02	5.57e-01	4.40e-01
Diseases associated with glycosylation precursor biosynthesis	18	6.82e-01	7.66e-01	0.10900	-4.14e-02	-1.00e-01	7.61e-01	4.61e-01
Autophagy	119	6.87e-01	7.71e-01	0.04630	-6.32e-03	4.59e-02	9.05e-01	3.88e-01
Telomere Extension By Telomerase	22	6.88e-01	7.71e-01	0.11600	9.68e-02	-6.41e-02	4.32e-01	6.03e-01
SHC-mediated cascade:FGFR3	12	6.92e-01	7.76e-01	0.12800	1.08e-01	6.90e-02	5.18e-01	6.79e-01
APC-Cdc20 mediated degradation of Nek2A	25	6.95e-01	7.78e-01	0.08770	6.76e-02	5.58e-02	5.58e-01	6.29e-01
Inositol phosphate metabolism	46	6.95e-01	7.78e-01	0.06680	2.21e-02	6.30e-02	7.96e-01	4.60e-01
Metabolism of porphyrins	23	6.96e-01	7.79e-01	0.10400	-1.84e-02	1.02e-01	8.79e-01	3.95e-01
Regulation of TP53 Activity through Methylation	17	7.02e-01	7.84e-01	0.12800	6.36e-02	-1.11e-01	6.50e-01	4.30e-01
GRB2 events in ERBB2 signaling	14	7.03e-01	7.85e-01	0.14200	-8.43e-02	1.14e-01	5.85e-01	4.60e-01
Activation of AMPK downstream of NMDARs	10	7.04e-01	7.85e-01	0.15300	1.52e-01	-1.63e-02	4.05e-01	9.29e-01
Diseases of carbohydrate metabolism	32	7.05e-01	7.86e-01	0.08060	-7.94e-02	-1.39e-02	4.37e-01	8.92e-01
Acyl chain remodelling of PS	16	7.08e-01	7.88e-01	0.11400	1.13e-01	1.44e-02	4.32e-01	9.21e-01
Oxidative Stress Induced Senescence	71	7.08e-01	7.88e-01	0.05210	4.83e-02	1.96e-02	4.82e-01	7.76e-01
Formation of the beta-catenin:TCF transactivating complex	40	7.10e-01	7.90e-01	0.07120	-7.00e-02	-1.31e-02	4.44e-01	8.86e-01
Heme biosynthesis	13	7.17e-01	7.97e-01	0.13500	-1.30e-01	3.48e-02	4.16e-01	8.28e-01
Nucleotide-like (purinergic) receptors	15	7.20e-01	7.99e-01	0.11200	-3.11e-02	-1.08e-01	8.35e-01	4.70e-01
Defective B4GALT7 causes EDS, progeroid type	20	7.24e-01	8.04e-01	0.09210	6.93e-02	6.08e-02	5.92e-01	6.38e-01
RNA Polymerase I Promoter Escape	37	7.26e-01	8.05e-01	0.06750	4.57e-02	4.97e-02	6.31e-01	6.01e-01
Signaling by ERBB2 TMD/JMD mutants	20	7.29e-01	8.07e-01	0.11000	-4.92e-02	9.85e-02	7.03e-01	4.46e-01
Inhibition of replication initiation of damaged DNA by RB1/E2F1	13	7.30e-01	8.07e-01	0.11300	8.26e-02	7.70e-02	6.06e-01	6.31e-01
Adenylate cyclase inhibitory pathway	13	7.30e-01	8.07e-01	0.12200	9.21e-03	1.22e-01	9.54e-01	4.47e-01
Interactions of Rev with host cellular proteins	36	7.31e-01	8.08e-01	0.06770	4.48e-02	5.08e-02	6.42e-01	5.98e-01
TNF signaling	44	7.33e-01	8.09e-01	0.07530	-4.61e-02	5.95e-02	5.97e-01	4.95e-01
ATF4 activates genes in response to endoplasmic reticulum stress	25	7.35e-01	8.11e-01	0.08930	-3.35e-03	8.92e-02	9.77e-01	4.40e-01
Striated Muscle Contraction	24	7.37e-01	8.12e-01	0.08350	3.60e-02	7.53e-02	7.60e-01	5.23e-01
FRS-mediated FGFR2 signaling	16	7.37e-01	8.12e-01	0.10800	1.22e-02	1.07e-01	9.33e-01	4.59e-01
Neurotransmitter release cycle	40	7.38e-01	8.12e-01	0.07360	1.84e-02	-7.13e-02	8.40e-01	4.36e-01
Vitamin B5 (pantothenate) metabolism	16	7.43e-01	8.17e-01	0.11100	-1.10e-01	8.58e-03	4.45e-01	9.53e-01
Sodium/Calcium exchangers	10	7.49e-01	8.23e-01	0.15000	1.32e-01	-7.05e-02	4.70e-01	7.00e-01
Constitutive Signaling by AKT1 E17K in Cancer	26	7.50e-01	8.23e-01	0.08840	-2.06e-02	8.60e-02	8.56e-01	4.48e-01
Metabolism of non-coding RNA	52	7.54e-01	8.26e-01	0.05920	-1.31e-03	5.92e-02	9.87e-01	4.60e-01
snRNP Assembly	52	7.54e-01	8.26e-01	0.05920	-1.31e-03	5.92e-02	9.87e-01	4.60e-01
Abacavir transport and metabolism	10	7.61e-01	8.33e-01	0.12200	5.19e-02	1.11e-01	7.76e-01	5.44e-01
PI3K Cascade	33	7.62e-01	8.33e-01	0.06590	-5.03e-02	-4.25e-02	6.17e-01	6.72e-01
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS)	12	7.63e-01	8.33e-01	0.11700	1.16e-01	1.56e-02	4.88e-01	9.25e-01
Diseases of hemostasis	12	7.63e-01	8.33e-01	0.11700	1.16e-01	1.56e-02	4.88e-01	9.25e-01
Rev-mediated nuclear export of HIV RNA	35	7.65e-01	8.35e-01	0.06410	5.39e-02	3.47e-02	5.81e-01	7.23e-01
PRC2 methylates histones and DNA	22	7.66e-01	8.35e-01	0.08180	3.26e-02	7.50e-02	7.92e-01	5.42e-01
O-linked glycosylation of mucins	50	7.66e-01	8.35e-01	0.05470	-1.87e-02	-5.15e-02	8.19e-01	5.29e-01
Acyl chain remodelling of PC	21	7.72e-01	8.41e-01	0.08060	-6.23e-02	-5.12e-02	6.21e-01	6.85e-01
A tetrasaccharide linker sequence is required for GAG synthesis	26	7.74e-01	8.43e-01	0.07900	-1.16e-03	-7.90e-02	9.92e-01	4.86e-01
Uptake and actions of bacterial toxins	25	7.75e-01	8.43e-01	0.09000	5.10e-02	-7.42e-02	6.59e-01	5.21e-01
WNT ligand biogenesis and trafficking	19	7.78e-01	8.45e-01	0.09910	-3.54e-02	9.26e-02	7.90e-01	4.85e-01
ERBB2 Regulates Cell Motility	13	7.82e-01	8.49e-01	0.12300	-1.01e-01	6.99e-02	5.29e-01	6.63e-01
Packaging Of Telomere Ends	13	7.84e-01	8.50e-01	0.11400	1.12e-01	-2.34e-02	4.85e-01	8.84e-01
DNA Double Strand Break Response	43	7.85e-01	8.52e-01	0.06680	-3.73e-02	5.55e-02	6.73e-01	5.29e-01
Deposition of new CENPA-containing nucleosomes at the centromere	32	7.88e-01	8.53e-01	0.06570	6.37e-02	1.61e-02	5.33e-01	8.75e-01
Nucleosome assembly	32	7.88e-01	8.53e-01	0.06570	6.37e-02	1.61e-02	5.33e-01	8.75e-01
HATs acetylate histones	87	7.89e-01	8.53e-01	0.04530	-1.74e-02	4.19e-02	7.80e-01	5.00e-01
SHC-mediated cascade:FGFR1	13	7.92e-01	8.56e-01	0.11100	-1.89e-02	1.09e-01	9.06e-01	4.95e-01
Maturation of nucleoprotein	10	7.92e-01	8.56e-01	0.13300	-5.78e-02	1.20e-01	7.52e-01	5.11e-01
GPCR ligand binding	264	7.95e-01	8.58e-01	0.02510	-6.59e-03	2.43e-02	8.54e-01	4.98e-01
Trafficking of GluR2-containing AMPA receptors	17	7.96e-01	8.58e-01	0.09770	9.47e-02	-2.42e-02	4.99e-01	8.63e-01
Metabolic disorders of biological oxidation enzymes	29	7.98e-01	8.60e-01	0.07910	6.11e-02	-5.02e-02	5.69e-01	6.40e-01
Gap junction assembly	13	7.99e-01	8.60e-01	0.10900	1.07e-01	-1.98e-02	5.03e-01	9.02e-01
Activation of gene expression by SREBF (SREBP)	42	8.03e-01	8.64e-01	0.06290	-5.74e-02	2.56e-02	5.20e-01	7.74e-01
IRS-mediated signalling	37	8.14e-01	8.75e-01	0.06560	-5.81e-02	3.05e-02	5.41e-01	7.48e-01
CS/DS degradation	14	8.15e-01	8.75e-01	0.08800	5.21e-02	7.10e-02	7.36e-01	6.46e-01
Chondroitin sulfate/dermatan sulfate metabolism	50	8.17e-01	8.77e-01	0.05500	-5.11e-02	2.03e-02	5.32e-01	8.04e-01
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	42	8.22e-01	8.82e-01	0.06140	-4.35e-02	4.33e-02	6.25e-01	6.27e-01
Metabolism of water-soluble vitamins and cofactors	114	8.23e-01	8.82e-01	0.03290	-1.08e-03	-3.29e-02	9.84e-01	5.45e-01
Signaling by NOTCH2	32	8.24e-01	8.82e-01	0.06990	-4.48e-02	5.37e-02	6.61e-01	5.99e-01
The phototransduction cascade	30	8.24e-01	8.82e-01	0.06260	-7.73e-03	-6.21e-02	9.42e-01	5.56e-01
Long-term potentiation	22	8.25e-01	8.82e-01	0.08340	4.72e-02	-6.88e-02	7.02e-01	5.77e-01
Downstream signaling of activated FGFR2	21	8.25e-01	8.82e-01	0.08140	-2.39e-02	7.79e-02	8.50e-01	5.37e-01
Acyl chain remodelling of PG	12	8.28e-01	8.84e-01	0.11000	-9.73e-02	5.23e-02	5.60e-01	7.54e-01
TNFR1-induced NFkappaB signaling pathway	26	8.30e-01	8.85e-01	0.06330	2.26e-02	5.91e-02	8.42e-01	6.02e-01
SUMOylation of intracellular receptors	29	8.32e-01	8.87e-01	0.06520	-6.48e-02	7.42e-03	5.46e-01	9.45e-01
Plasma lipoprotein assembly, remodeling, and clearance	64	8.33e-01	8.87e-01	0.04560	4.36e-02	-1.34e-02	5.47e-01	8.53e-01
Defective B3GAT3 causes JDSSDHD	20	8.34e-01	8.88e-01	0.06990	3.56e-02	6.02e-02	7.83e-01	6.41e-01
Acyl chain remodelling of PI	11	8.38e-01	8.91e-01	0.10700	1.04e-01	-2.71e-02	5.52e-01	8.76e-01
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	26	8.39e-01	8.92e-01	0.06220	1.73e-02	5.97e-02	8.79e-01	5.98e-01
Adenylate cyclase activating pathway	10	8.40e-01	8.92e-01	0.11900	7.50e-02	-9.19e-02	6.82e-01	6.15e-01
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism	12	8.45e-01	8.96e-01	0.10600	6.83e-02	-8.14e-02	6.82e-01	6.25e-01
alpha-linolenic acid (ALA) metabolism	12	8.45e-01	8.96e-01	0.10600	6.83e-02	-8.14e-02	6.82e-01	6.25e-01
N-Glycan antennae elongation	14	8.48e-01	8.99e-01	0.09420	8.65e-02	-3.74e-02	5.75e-01	8.08e-01
NCAM1 interactions	33	8.49e-01	8.99e-01	0.05770	6.63e-03	-5.73e-02	9.47e-01	5.69e-01
Pexophagy	11	8.51e-01	8.99e-01	0.09210	8.89e-02	2.38e-02	6.10e-01	8.91e-01
Nicotinate metabolism	30	8.51e-01	8.99e-01	0.05330	3.61e-02	3.92e-02	7.32e-01	7.10e-01
Transport of the SLBP Dependant Mature mRNA	36	8.54e-01	9.02e-01	0.04890	2.18e-02	4.38e-02	8.21e-01	6.50e-01
Class A/1 (Rhodopsin-like receptors)	191	8.55e-01	9.03e-01	0.02580	-1.56e-02	2.05e-02	7.10e-01	6.26e-01
N-glycan antennae elongation in the medial/trans-Golgi	22	8.58e-01	9.05e-01	0.07250	-2.91e-02	6.64e-02	8.13e-01	5.90e-01
IL-6-type cytokine receptor ligand interactions	15	8.61e-01	9.08e-01	0.07590	7.35e-02	1.91e-02	6.22e-01	8.98e-01
Transport of the SLBP independent Mature mRNA	35	8.62e-01	9.08e-01	0.04810	2.18e-02	4.29e-02	8.23e-01	6.61e-01
FGFR2 alternative splicing	26	8.63e-01	9.08e-01	0.05520	4.74e-02	2.83e-02	6.76e-01	8.03e-01
NRAGE signals death through JNK	57	8.65e-01	9.09e-01	0.04330	-1.43e-02	4.09e-02	8.52e-01	5.93e-01
SHC-mediated cascade:FGFR4	12	8.65e-01	9.09e-01	0.09310	-2.57e-02	8.95e-02	8.77e-01	5.92e-01
RNA Polymerase I Transcription Termination	27	8.67e-01	9.09e-01	0.05290	-3.44e-02	-4.01e-02	7.57e-01	7.18e-01
RHO GTPases activate KTN1	11	8.67e-01	9.09e-01	0.10200	-7.32e-02	7.17e-02	6.74e-01	6.81e-01
Plasma lipoprotein clearance	32	8.67e-01	9.09e-01	0.05990	-4.62e-02	3.80e-02	6.51e-01	7.10e-01
Peroxisomal lipid metabolism	28	8.69e-01	9.10e-01	0.06370	-4.59e-02	4.42e-02	6.74e-01	6.86e-01
Association of TriC/CCT with target proteins during biosynthesis	39	8.70e-01	9.10e-01	0.04430	-4.01e-02	-1.88e-02	6.65e-01	8.39e-01
FRS-mediated FGFR3 signaling	14	8.70e-01	9.10e-01	0.08220	-1.21e-02	8.13e-02	9.37e-01	5.99e-01
Regulation of PTEN mRNA translation	11	8.73e-01	9.13e-01	0.08250	-3.35e-02	-7.53e-02	8.47e-01	6.65e-01
Xenobiotics	13	8.73e-01	9.13e-01	0.08020	8.00e-02	5.76e-03	6.17e-01	9.71e-01
MTOR signalling	41	8.75e-01	9.13e-01	0.04410	4.34e-02	7.75e-03	6.31e-01	9.32e-01
Surfactant metabolism	20	8.78e-01	9.16e-01	0.06320	-6.30e-02	-5.36e-03	6.26e-01	9.67e-01
PI-3K cascade:FGFR3	12	8.81e-01	9.18e-01	0.08190	-8.19e-02	-1.12e-03	6.23e-01	9.95e-01
Lysine catabolism	12	8.82e-01	9.18e-01	0.07940	-7.86e-02	-1.16e-02	6.37e-01	9.45e-01
NR1H2 and NR1H3-mediated signaling	44	8.82e-01	9.19e-01	0.04530	1.31e-02	-4.34e-02	8.80e-01	6.19e-01
Amino acids regulate mTORC1	51	8.84e-01	9.19e-01	0.03830	3.81e-02	4.59e-03	6.38e-01	9.55e-01
Downstream signaling of activated FGFR3	19	8.85e-01	9.19e-01	0.07210	-4.56e-02	5.58e-02	7.31e-01	6.74e-01
Signaling by FGFR3 in disease	16	8.86e-01	9.20e-01	0.06850	4.24e-03	6.84e-02	9.77e-01	6.36e-01
Signaling by FGFR3 point mutants in cancer	16	8.86e-01	9.20e-01	0.06850	4.24e-03	6.84e-02	9.77e-01	6.36e-01
Negative regulation of TCF-dependent signaling by WNT ligand antagonists	14	8.89e-01	9.22e-01	0.08190	4.99e-02	-6.50e-02	7.47e-01	6.74e-01
Cell-cell junction organization	51	8.90e-01	9.23e-01	0.03500	1.84e-02	2.97e-02	8.20e-01	7.14e-01
Nucleotide salvage	21	8.91e-01	9.23e-01	0.05890	5.89e-02	8.91e-04	6.40e-01	9.94e-01
Synthesis of IP2, IP, and Ins in the cytosol	14	8.93e-01	9.24e-01	0.08030	4.67e-02	-6.54e-02	7.62e-01	6.72e-01
Resolution of D-Loop Structures	33	8.95e-01	9.25e-01	0.05220	3.75e-02	-3.63e-02	7.09e-01	7.18e-01
Phenylalanine and tyrosine metabolism	10	8.96e-01	9.26e-01	0.08620	-1.27e-02	8.53e-02	9.44e-01	6.41e-01
RMTs methylate histone arginines	36	9.01e-01	9.30e-01	0.03990	3.62e-02	1.68e-02	7.07e-01	8.62e-01
Purine catabolism	18	9.01e-01	9.30e-01	0.06470	-1.94e-02	6.17e-02	8.87e-01	6.50e-01
Metabolism of steroids	128	9.02e-01	9.30e-01	0.02090	1.01e-02	1.83e-02	8.43e-01	7.21e-01
Other interleukin signaling	19	9.03e-01	9.30e-01	0.05390	2.62e-02	4.72e-02	8.43e-01	7.22e-01
Recycling of bile acids and salts	12	9.04e-01	9.30e-01	0.07430	-5.58e-03	7.40e-02	9.73e-01	6.57e-01
P2Y receptors	11	9.04e-01	9.30e-01	0.07920	1.37e-02	-7.80e-02	9.37e-01	6.54e-01
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux	35	9.09e-01	9.35e-01	0.04390	1.08e-02	-4.25e-02	9.12e-01	6.63e-01
Reversible hydration of carbon dioxide	10	9.11e-01	9.35e-01	0.08290	2.73e-02	-7.83e-02	8.81e-01	6.68e-01
Hyaluronan uptake and degradation	12	9.18e-01	9.42e-01	0.07140	6.91e-02	-1.78e-02	6.79e-01	9.15e-01
TNFR1-induced proapoptotic signaling	13	9.24e-01	9.47e-01	0.07000	-4.43e-02	5.41e-02	7.82e-01	7.35e-01
Regulated proteolysis of p75NTR	11	9.25e-01	9.47e-01	0.06720	8.96e-04	6.72e-02	9.96e-01	7.00e-01
Inactivation, recovery and regulation of the phototransduction cascade	29	9.25e-01	9.47e-01	0.03860	-1.58e-02	-3.52e-02	8.83e-01	7.43e-01
PKMTs methylate histone lysines	44	9.25e-01	9.47e-01	0.03750	-3.04e-02	2.20e-02	7.27e-01	8.01e-01
Visual phototransduction	83	9.27e-01	9.47e-01	0.02260	-8.41e-03	-2.09e-02	8.95e-01	7.42e-01
Prolactin receptor signaling	11	9.27e-01	9.47e-01	0.07450	-5.10e-02	5.43e-02	7.70e-01	7.55e-01
Carboxyterminal post-translational modifications of tubulin	28	9.28e-01	9.47e-01	0.04600	-3.92e-02	2.39e-02	7.19e-01	8.27e-01
mRNA Splicing - Minor Pathway	50	9.32e-01	9.51e-01	0.03370	2.19e-02	-2.57e-02	7.89e-01	7.54e-01
Transport of Mature mRNAs Derived from Intronless Transcripts	42	9.34e-01	9.52e-01	0.03250	-1.24e-03	3.25e-02	9.89e-01	7.16e-01
HS-GAG biosynthesis	28	9.36e-01	9.54e-01	0.04010	-5.94e-03	3.96e-02	9.57e-01	7.17e-01
Macroautophagy	108	9.37e-01	9.54e-01	0.01850	6.19e-03	1.74e-02	9.12e-01	7.55e-01
Transport of Mature mRNA Derived from an Intronless Transcript	41	9.40e-01	9.55e-01	0.03150	-1.78e-03	3.15e-02	9.84e-01	7.28e-01
PI-3K cascade:FGFR2	14	9.40e-01	9.55e-01	0.05960	-4.41e-02	4.00e-02	7.75e-01	7.95e-01
Tryptophan catabolism	14	9.41e-01	9.55e-01	0.05930	-3.85e-02	4.51e-02	8.03e-01	7.70e-01
KSRP (KHSRP) binds and destabilizes mRNA	16	9.41e-01	9.55e-01	0.04480	2.96e-02	3.36e-02	8.38e-01	8.16e-01
GABA synthesis, release, reuptake and degradation	13	9.43e-01	9.57e-01	0.05930	3.00e-02	-5.12e-02	8.51e-01	7.49e-01
Interleukin-37 signaling	19	9.44e-01	9.57e-01	0.04940	-3.54e-02	3.45e-02	7.89e-01	7.95e-01
Interleukin-15 signaling	14	9.48e-01	9.60e-01	0.05290	-5.02e-02	1.67e-02	7.45e-01	9.14e-01
Protein methylation	14	9.49e-01	9.61e-01	0.04500	1.96e-02	4.05e-02	8.99e-01	7.93e-01
Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)	10	9.51e-01	9.62e-01	0.06260	5.31e-02	-3.30e-02	7.71e-01	8.56e-01
Chondroitin sulfate biosynthesis	20	9.51e-01	9.62e-01	0.04470	-3.48e-02	2.81e-02	7.88e-01	8.28e-01
Activation of HOX genes during differentiation	69	9.64e-01	9.73e-01	0.02060	-1.08e-02	1.76e-02	8.77e-01	8.01e-01
Activation of anterior HOX genes in hindbrain development during early embryogenesis	69	9.64e-01	9.73e-01	0.02060	-1.08e-02	1.76e-02	8.77e-01	8.01e-01
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	18	9.69e-01	9.78e-01	0.03650	-1.61e-02	3.28e-02	9.06e-01	8.10e-01
Metabolism of vitamins and cofactors	175	9.70e-01	9.78e-01	0.01180	-9.57e-03	6.86e-03	8.27e-01	8.76e-01
Resolution of D-loop Structures through Holliday Junction Intermediates	32	9.78e-01	9.85e-01	0.02380	1.83e-02	-1.51e-02	8.58e-01	8.82e-01
Regulation of gene expression by Hypoxia-inducible Factor	11	9.79e-01	9.86e-01	0.03900	-2.90e-02	2.62e-02	8.68e-01	8.80e-01
Glycosaminoglycan metabolism	114	9.82e-01	9.88e-01	0.01110	9.52e-03	-5.73e-03	8.61e-01	9.16e-01
Diseases of metabolism	217	9.86e-01	9.91e-01	0.00596	2.54e-03	5.40e-03	9.49e-01	8.91e-01
Eicosanoid ligand-binding receptors	11	9.88e-01	9.92e-01	0.02450	-1.23e-02	-2.11e-02	9.44e-01	9.03e-01
mRNA decay by 3' to 5' exoribonuclease	15	9.89e-01	9.92e-01	0.02340	2.24e-02	-6.54e-03	8.80e-01	9.65e-01
HDMs demethylate histones	23	9.94e-01	9.97e-01	0.01430	-6.97e-03	1.25e-02	9.54e-01	9.18e-01
Regulation of FOXO transcriptional activity by acetylation	10	9.95e-01	9.97e-01	0.01630	-6.64e-03	-1.49e-02	9.71e-01	9.35e-01
Repression of WNT target genes	14	9.98e-01	9.99e-01	0.00971	4.01e-03	8.84e-03	9.79e-01	9.54e-01
Glycogen storage diseases	15	9.99e-01	9.99e-01	0.00706	-6.92e-03	1.39e-03	9.63e-01	9.93e-01
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10	10	9.99e-01	9.99e-01	0.00697	-6.96e-03	3.71e-04	9.70e-01	9.98e-01

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Detailed Gene set reports

Olfactory Signaling Pathway

Olfactory Signaling Pathway

metric	value
setSize	209
pMANOVA	2.09e-38
p.adjustMANOVA	2.93e-35
s.dist	0.477
s.diabetes	-0.216
s.mitoG	-0.425
p.diabetes	7.91e-08
p.mitoG	3.03e-26

Top 20 genes

Gene	diabetes	mitoG
OR10AG1	-6532.0	-6536.0
OR4C15	-5975.0	-6779.0
OR5B3	-5709.0	-6638.0
OR8G1	-5330.5	-6730.5
OR8G5	-5330.5	-6730.5
OR2AG1	-5383.5	-6588.5
OR2AG2	-5383.5	-6588.5
OR8K3	-5213.0	-6427.0
OR2T29	-5177.0	-6137.0
OR2T4	-5177.0	-6137.0
OR2T5	-5177.0	-6137.0
OR51Q1	-6613.0	-4520.0
OR10Q1	-4915.0	-6061.0
OR7D4	-4403.0	-6079.0
OR1F1	-4773.0	-5398.0
OR4A16	-3763.0	-6781.0
OR5AL1	-4425.0	-5493.0
OR6X1	-3559.0	-6602.0
OR4Q3	-3450.0	-6406.0
OR8K5	-3684.0	-5439.0

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
GNAL	-869.0	2969.0
GNB1	1685.0	7974.0
GNGT1	1972.0	5695.0
OR10A2	-1615.5	-5711.5
OR10A3	2457.5	-3360.5
OR10A5	-1615.5	-5711.5
OR10A6	2457.5	-3360.5
OR10A7	2712.0	-1349.0
OR10AD1	-3955.0	-4370.0
OR10AG1	-6532.0	-6536.0
OR10C1	-2872.0	3205.0
OR10D3	-2252.0	-350.0
OR10G6	-5705.0	-2209.0
OR10H1	-2606.0	-3818.0
OR10H2	-2606.0	-3818.0
OR10H3	-4761.5	-2534.5
OR10H4	-4761.5	-2534.5
OR10H5	-2606.0	-3818.0
OR10P1	-3736.0	277.0
OR10Q1	-4915.0	-6061.0
OR10S1	1731.0	-5614.0
OR10V1	0.0	789.0
OR10W1	1525.0	-3747.0
OR10X1	-1440.0	-245.0
OR11H7	-5063.0	-3296.0
OR11L1	-5319.0	131.0
OR12D3	2342.0	-5876.0
OR13C3	-1361.0	2376.0
OR13H1	-3614.0	-1722.0
OR13J1	2272.0	-3585.0
OR14C36	-3527.0	1868.0
OR14I1	2467.0	-3211.0
OR1A1	-3768.5	2904.5
OR1A2	-3768.5	2904.5
OR1B1	-1518.0	-4138.0
OR1F1	-4773.0	-5398.0
OR1I1	1108.0	-271.0
OR1N1	-547.0	-5999.0
OR1N2	-1054.0	-5518.0
OR2A12	-4300.0	-953.0
OR2A14	5466.0	-3634.0
OR2A4	-87.5	-1685.5
OR2A5	999.0	-5931.0
OR2A7	-87.5	-1685.5
OR2AG1	-5383.5	-6588.5
OR2AG2	-5383.5	-6588.5
OR2AK2	-1303.0	-3316.0
OR2AP1	1851.0	-3761.0
OR2B6	1764.0	-5241.0
OR2C1	-1818.0	-5150.0
OR2D2	-5314.0	-426.0
OR2D3	-2149.0	-1241.0
OR2F1	-1491.5	-516.5
OR2F2	-1491.5	-516.5
OR2H1	-2698.0	375.0
OR2H2	-3149.0	-5619.0
OR2J1	4584.0	-4421.0
OR2J2	4584.0	-4421.0
OR2J3	4584.0	-4421.0
OR2K2	-2010.0	1448.0
OR2L2	-3380.5	-1943.5
OR2L3	-3380.5	-1943.5
OR2L5	-3380.5	-1943.5
OR2L8	-3380.5	-1943.5
OR2T1	387.0	-4834.0
OR2T29	-5177.0	-6137.0
OR2T4	-5177.0	-6137.0
OR2T5	-5177.0	-6137.0
OR2T6	-3486.0	886.0
OR2V1	2357.0	-3628.0
OR2V2	3258.0	-2820.0
OR2W1	-887.0	-5117.0
OR2W3	3447.0	-5264.0
OR2Y1	520.0	-6783.0
OR4A16	-3763.0	-6781.0
OR4A47	-1039.0	2993.0
OR4A5	-4426.5	1579.5
OR4A8	-4426.5	1579.5
OR4B1	-596.0	-628.0
OR4C11	972.0	-5078.0
OR4C13	-2227.5	1176.5
OR4C15	-5975.0	-6779.0
OR4C16	-2196.0	365.0
OR4C3	-1427.0	343.0
OR4C45	-1978.0	-6021.0
OR4C46	-2227.5	1176.5
OR4C5	-1676.0	-6152.0
OR4D11	-254.0	-2572.0
OR4D2	904.0	-5776.0
OR4D5	2004.0	-1171.0
OR4D6	-4807.0	4102.0
OR4F15	3126.0	-5364.0
OR4F17	-1005.0	-5259.0
OR4F21	-3529.5	-498.5
OR4F3	-3529.5	-498.5
OR4F4	-1005.0	-5259.0
OR4F5	-1005.0	-5259.0
OR4F6	-2085.0	-5842.0
OR4K1	-2871.0	1777.0
OR4K15	-2336.0	2073.0
OR4K5	-3840.0	7563.0
OR4M1	1256.5	-4614.5
OR4M2	1256.5	-4614.5
OR4N4	-4652.0	1898.0
OR4P4	-2183.0	-5402.0
OR4Q3	-3450.0	-6406.0
OR4S2	-4538.0	-3613.0
OR4X2	-2257.0	-5505.0
OR51A7	-2353.0	4321.0
OR51B4	-2421.0	-2889.0
OR51E1	-892.0	3832.0
OR51E2	1389.0	-1746.0
OR51G1	789.0	-2341.0
OR51Q1	-6613.0	-4520.0
OR51S1	-2695.0	1245.0
OR51V1	3540.0	-5984.0
OR52A5	-2836.0	1656.0
OR52B2	-5034.0	4526.0
OR52D1	-5069.0	-3503.0
OR52E6	949.5	-6385.5
OR52E8	949.5	-6385.5
OR52H1	-1218.0	-6314.0
OR52I1	-13.5	2279.5
OR52I2	-13.5	2279.5
OR52K2	-2331.0	-5926.0
OR52M1	-2750.0	5676.0
OR52N2	-1282.0	-5772.0
OR56A3	1307.0	-424.0
OR56B2P	-763.0	-701.0
OR56B4	-4405.0	-660.0
OR5A1	1968.0	-3286.0
OR5A2	-1939.0	6129.0
OR5AC1	-3250.0	-1029.0
OR5AL1	-4425.0	-5493.0
OR5AN1	-2087.0	488.0
OR5AP2	1291.0	-6097.0
OR5B12	1509.0	-5462.0
OR5B3	-5709.0	-6638.0
OR5D14	-1767.0	-5389.0
OR5D18	-2307.0	-1013.0
OR5H1	2899.5	-1678.5
OR5H14	2899.5	-1678.5
OR5H15	2899.5	-1678.5
OR5H2	2899.5	-1678.5
OR5H6	2899.5	-1678.5
OR5I1	-595.0	-1801.0
OR5K1	1333.5	-6332.5
OR5K2	1333.5	-6332.5
OR5K3	6502.0	-4464.0
OR5L1	1271.5	-6716.5
OR5L2	1271.5	-6716.5
OR5M1	-587.5	-4801.5
OR5M10	-587.5	-4801.5
OR5M11	-4295.0	-2813.0
OR5M3	-7018.0	1713.0
OR5M9	-3581.5	1566.5
OR5P2	-1863.0	-6780.0
OR5V1	-1226.0	1270.0
OR5W2	-1650.0	-1270.0
OR6A2	-3361.0	3663.0
OR6B2	-24.5	-6012.5
OR6B3	-24.5	-6012.5
OR6C1	-4919.0	-2611.0
OR6C6	-654.0	-5957.0
OR6C65	4160.0	-3311.0
OR6C68	-2168.0	-1400.0
OR6C70	-727.0	-2396.0
OR6C76	-1452.0	-2198.0
OR6K2	-3420.0	-3849.0
OR6N2	-483.0	-3449.0
OR6S1	5654.0	-3043.0
OR6X1	-3559.0	-6602.0
OR6Y1	-3127.0	1731.0
OR7A10	1848.0	-4799.0
OR7A17	1848.0	-4799.0
OR7A5	1848.0	-4799.0
OR7C2	6881.0	-2433.0
OR7D4	-4403.0	-6079.0
OR7E24	-4864.0	4086.0
OR7G1	2812.0	-6343.0
OR7G2	2862.0	-36.0
OR8A1	-1173.0	-4925.0
OR8B2	-1568.5	-2264.5
OR8B3	-1568.5	-2264.5
OR8B8	-2771.0	1299.0
OR8G1	-5330.5	-6730.5
OR8G5	-5330.5	-6730.5
OR8H1	-1653.0	3580.0
OR8H2	-1653.0	3580.0
OR8H3	-1653.0	3580.0
OR8J1	-4734.5	5634.5
OR8J3	-4734.5	5634.5
OR8K3	-5213.0	-6427.0
OR8K5	-3684.0	-5439.0
OR8S1	1584.0	-4226.0
OR8U1	-536.0	-5955.0
OR9A1P	7476.0	-6030.0
OR9A2	2675.0	492.0
OR9A4	3554.0	-4308.0
OR9I1	2198.0	-4498.0
OR9K2	-5081.0	-2417.0
REEP1	-1074.0	-5002.0
REEP2	4.0	828.0
REEP3	-3229.0	6734.0
REEP4	3119.0	-2877.0
REEP5	-7146.0	3339.0
REEP6	8248.0	6316.0
RTP3	-4508.0	-2884.0
RTP4	-2887.0	3910.0

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Infectious disease

Infectious disease

metric	value
setSize	693
pMANOVA	4.47e-24
p.adjustMANOVA	3.13e-21
s.dist	0.239
s.diabetes	-0.0548
s.mitoG	0.232
p.diabetes	0.0146
p.mitoG	3.51e-25

Top 20 genes

Gene	diabetes	mitoG
IGHV1-69	-7353.5	8845.5
IGKV4-1	-7301.0	8840.0
HSP90AA1	-7286.0	8742.0
PTGES3	-7067.0	8733.0
PSMC6	-6851.0	8666.0
UBB	-7104.0	8341.0
CANX	-6936.0	8532.0
KPNA4	-6802.0	8691.0
DNAJC3	-7149.0	8179.0
PSME4	-6830.0	8511.0
SKP1	-6803.0	8394.0
PSMD1	-6497.0	8619.0
HDAC2	-6396.0	8620.0
ITGB1	-6241.0	8758.0
GNAI1	-6368.0	8547.0
JAK1	-6481.0	8390.0
NT5E	-7042.0	7643.0
TBL1X	-7106.5	7510.5
RPN1	-7121.0	7464.0
DYNLL1	-6952.0	7645.0

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
AAAS	5561.0	-2261.0
ABI1	-4630.0	8305.0
ABI2	4154.0	8369.0
ABL1	5557.0	-3567.0
ACE2	8047.0	1319.0
ACTB	-4152.0	7953.0
ACTG1	-1502.0	1482.0
ACTR2	-5189.0	7356.0
ACTR3	-3716.0	8206.0
ADAM17	-5121.0	3275.0
ADCY1	-4196.0	1876.0
ADCY2	5891.0	1358.0
ADCY3	-351.0	4656.0
ADCY4	-237.0	7618.0
ADCY5	2277.0	2395.0
ADCY6	7278.0	-6203.0
ADCY7	-5272.0	-2210.0
ADCY8	3778.0	-3880.0
ADCY9	2137.0	-5459.0
ADCYAP1	-2784.0	6784.0
ADCYAP1R1	6820.0	4772.0
ADM	7469.0	6606.0
ADM2	-2536.0	-3876.0
ADORA2A	-2349.0	1070.0
ADORA2B	-2957.0	819.0
ADRB1	5207.0	-4492.0
ADRB2	-6910.0	4340.0
AHCYL1	-5585.0	5114.0
ANTXR1	7856.0	7620.0
ANTXR2	1970.0	5230.0
AP1B1	5867.0	-3224.0
AP1G1	-6928.0	3255.0
AP1M1	2796.0	-3928.0
AP1M2	7170.0	-121.0
AP1S1	-667.0	-1428.0
AP1S2	-2308.0	7787.0
AP1S3	483.0	-6543.0
AP2A1	3192.0	-2941.0
AP2A2	-6231.0	249.0
AP2B1	-3990.0	7426.0
AP2M1	5073.0	2926.0
AP2S1	587.0	7094.0
ARF1	-5273.0	7470.0
ARID4A	-4003.0	6886.0
ARID4B	1679.0	5415.0
ARPC1A	-1009.0	-3070.0
ARPC1B	7126.0	2266.0
ARPC2	-4512.0	8767.0
ARPC3	-5747.0	8757.0
ARPC4	3077.0	1525.0
ARPC5	920.0	7514.0
ATP1A1	8085.0	4179.0
ATP1A2	1265.0	3781.0
ATP1A3	-3332.5	4126.5
ATP1B1	8146.0	7502.0
ATP1B2	-1075.0	6478.0
ATP1B3	-1025.0	8436.0
ATP6V1H	-1095.0	8501.0
AVPR2	4980.0	2853.0
B2M	5339.0	4978.0
BAIAP2	7911.0	534.0
BANF1	3561.0	-458.0
BRD4	-4805.0	1284.0
BRK1	751.0	1659.0
BRMS1	1673.0	7971.0
BTK	-5279.0	5486.0
BTRC	3218.0	-5334.0
C3	7675.0	3404.0
C3AR1	-1253.0	7488.0
CALCA	-3485.0	-2743.0
CALCR	-2793.0	1335.0
CALCRL	-3264.0	8776.0
CALM1	-4401.0	8702.0
CALR	-7105.0	5809.0
CANX	-6936.0	8532.0
CASP1	-1051.0	1558.0
CBL	-6462.0	4306.0
CBLL1	175.0	4700.0
CCNH	-5547.0	6108.0
CCNK	1018.0	3257.0
CCNT1	-709.0	6941.0
CCNT2	-1826.0	951.0
CCR5	-1106.0	281.0
CD163	-2470.0	7418.0
CD247	1213.0	-5666.0
CD28	-4408.0	5134.0
CD3G	-1784.0	-3919.0
CD4	409.0	5008.0
CD8B	-2337.5	645.5
CD9	7375.0	4550.0
CDC42	-5961.0	8129.0
CDH1	-1038.0	5837.0
CDK7	-258.0	3661.0
CDK9	315.0	-5322.0
CEBPD	3288.0	6984.0
CHD3	-7230.0	-2465.0
CHD4	5349.5	5970.5
CHMP1A	2980.0	-5932.0
CHMP2A	3891.0	6246.0
CHMP2B	-3672.0	8606.0
CHMP3	-5181.5	8584.5
CHMP4B	7103.0	2636.0
CHMP4C	6678.0	1533.0
CHMP5	-4004.0	8542.0
CHMP6	4209.0	-2043.0
CHMP7	-57.0	-2549.0
CLTA	-2807.0	2774.0
CLTC	-4493.0	8248.0
COMT	-7046.0	5137.0
CORO1A	-3183.0	-17.0
CPSF4	-267.0	514.0
CRBN	2027.0	6641.0
CREB1	-6809.0	5166.0
CRHR2	-903.0	2018.0
CRK	-3124.0	6926.0
CTDP1	6939.0	2918.0
CTNNB1	-6022.0	2664.0
CTNND1	5833.0	1565.0
CUL5	-5371.0	8605.0
CXCR4	4516.0	7547.0
CYBA	-4719.0	-4200.0
CYFIP1	3175.0	7476.0
CYFIP2	7791.0	-143.0
CYSLTR1	-4800.0	4502.0
DAD1	-601.0	-4283.0
DAXX	-867.0	1599.0
DBP	8002.0	-5295.0
DDOST	-5017.0	2674.0
DDX5	-3313.0	-2478.0
DNAJC3	-7149.0	8179.0
DOCK1	2243.0	382.0
DOCK2	-5657.0	5085.0
DPEP1	1301.0	5412.0
DPEP2	3373.0	1639.0
DRD1	-1465.0	4255.0
DUSP16	-3468.0	8092.0
DUT	1159.0	688.0
DVL1	6741.0	-6179.0
DVL2	7754.0	-6212.0
DVL3	7325.0	-4734.0
DYNC1H1	4822.0	2594.0
DYNC1I1	3045.0	-5230.0
DYNC1I2	-251.0	7398.0
DYNC1LI1	2249.0	7292.0
DYNC1LI2	-1436.0	1861.0
DYNLL1	-6952.0	7645.0
DYNLL2	4932.0	-5028.0
EDEM2	-3522.0	-3508.0
EED	-1977.0	6430.0
EEF2	-3312.0	2063.0
EGFR	-6023.0	1902.0
EIF2AK2	4174.0	5292.0
ELK1	3201.0	-1060.0
ELL	6782.0	805.0
ELMO1	-4833.0	4917.0
ELMO2	6218.0	-536.0
ELOA	7447.0	7874.0
ELOB	6643.0	3269.0
ELOC	-3325.0	7837.0
ENO1	8244.0	7737.0
ENTPD1	6740.0	7163.0
ENTPD5	6385.0	3766.0
EPS15	-5197.0	5904.0
ERCC2	6295.0	-6411.0
ERCC3	-2263.0	1771.0
EZH2	13.0	1789.0
FAU	6809.0	7710.0
FCGR1A	-5675.5	4265.5
FCGR2A	-7297.0	5966.0
FCGR3A	-5407.5	6212.5
FEN1	-277.0	298.0
FGR	-3144.0	378.0
FKBP1A	-2857.5	-1534.5
FKBP4	-7096.0	-111.0
FURIN	3696.0	-3590.0
FUT8	-5026.0	4575.0
FXYD1	-583.0	7074.0
FXYD2	-3344.5	4429.5
FXYD4	1149.0	10.0
FXYD6	412.0	7190.0
FYN	-2200.0	6221.0
FZD7	4413.0	-2110.0
GALNT1	-6827.0	6806.0
GANAB	-6749.0	-2365.0
GATAD2A	-190.0	5669.0
GATAD2B	-2967.0	5239.0
GGT1	-7165.0	-1432.0
GGT5	1563.0	6027.0
GHRHR	3635.0	3159.0
GLP1R	-3107.0	1309.0
GNAI1	-6368.0	8547.0
GNAI2	6737.0	5825.0
GNAI3	-3916.0	8277.0
GNAS	-2825.0	5946.0
GNAZ	-1947.0	4122.0
GNB1	1685.0	7974.0
GNB2	5389.0	-1847.0
GNB4	-4648.0	2711.0
GNB5	4543.0	3032.0
GNG10	5845.0	2921.0
GNG11	-2960.0	5884.0
GNG12	-1212.0	6898.0
GNG2	4011.0	7569.0
GNG3	-1825.0	1443.0
GNG4	-653.0	-591.0
GNG5	-2879.0	-1254.0
GNG7	1904.0	-4062.0
GNG8	499.0	-762.0
GNGT1	1972.0	5695.0
GNGT2	-1053.0	5102.0
GPR176	-1437.0	7990.0
GPR20	-684.0	-2071.0
GPR27	-995.0	4679.0
GPR39	1163.0	-286.0
GPS2	1228.0	2826.0
GRB2	3285.0	1922.0
GRSF1	4054.0	-1610.0
GSK3A	3838.0	1447.0
GSK3B	-5423.0	7184.0
GTF2A1	-940.0	5933.0
GTF2A2	505.0	6107.0
GTF2B	-1890.0	6217.0
GTF2E1	-2217.0	6482.0
GTF2E2	-2968.0	2878.0
GTF2F1	373.0	6337.0
GTF2F2	-1458.0	7912.0
GTF2H1	-6106.0	8498.0
GTF2H2	-3368.5	7043.5
GTF2H3	-1824.0	-2008.0
GTF2H4	3818.0	-4105.0
GTF2H5	1998.0	783.0
H2AC20	7413.0	2470.0
H2AC21	6478.0	633.0
H2AW	-5259.0	4003.0
H2BC11	3900.0	-3127.0
H2BC14	1703.0	1613.0
H2BC18	4839.0	6098.0
H2BC5	3445.0	-761.0
H3C15	7988.0	2080.0
HBEGF	-6694.0	-80.0
HCK	-3484.0	-1326.0
HDAC1	-3050.0	4701.0
HDAC2	-6396.0	8620.0
HDAC3	5142.0	-772.0
HGS	-1920.0	704.0
HMG20B	6566.0	-1264.0
HMGA1	7803.0	-1488.0
HNRNPK	-808.0	7246.0
HRH2	-2405.0	714.0
HSP90AA1	-7286.0	8742.0
HSP90AB1	-7306.0	5626.0
HSPA1A	-7272.5	7293.5
IFNAR1	-1479.0	4534.0
IFNAR2	-850.5	5706.5
IFNGR1	-4655.0	6148.0
IFNGR2	4633.0	5019.0
IGHV1-69	-7353.5	8845.5
IGHV2-5	4395.0	4965.0
IGHV2-70	4395.0	4965.0
IGHV7-81	517.5	7570.5
IGKC	-2925.0	7318.0
IGKV1-12	2052.5	4944.5
IGKV1-17	2052.5	4944.5
IGKV1-39	2052.5	4944.5
IGKV1D-12	2052.5	4944.5
IGKV1D-39	2052.5	4944.5
IGKV2-30	101.5	8396.5
IGKV2D-30	101.5	8396.5
IGKV4-1	-7301.0	8840.0
IGKV5-2	-5895.0	8671.0
IGLV4-60	-3537.5	3617.5
IGLV4-69	-3537.5	3617.5
IL18	4167.0	-3592.0
IL1A	-1142.0	1688.0
IL1B	-6242.0	3978.0
IL1R1	3443.0	7288.0
IL6R	-730.0	6215.0
IMPDH1	1190.0	4821.0
IMPDH2	4946.0	4658.0
IPO5	7411.0	3285.0
IRS1	7064.0	-5549.0
ISG15	-1124.0	-2998.0
ITGA4	-6762.0	7.0
ITGB1	-6241.0	8758.0
ITPR1	-2727.0	2512.0
ITPR2	4185.0	-2206.0
ITPR3	7844.0	5234.0
JAK1	-6481.0	8390.0
JAK2	-2268.0	5565.0
JAK3	7556.0	-6301.0
JUN	581.0	5314.0
KDM1A	5314.0	-44.0
KPNA1	-5632.0	8815.0
KPNA2	2229.0	5432.0
KPNA3	-1498.0	8389.0
KPNA4	-6802.0	8691.0
KPNB1	-1668.0	5829.0
LCK	-2194.0	5687.0
LHCGR	-5643.5	-1575.5
LIG1	4884.0	892.0
LIG4	-3349.0	7573.0
LTF	-2111.0	1638.0
LYN	-4685.0	8216.0
MAGT1	-6822.0	7703.0
MAN1B1	-1873.0	-6055.0
MAN2A1	8162.0	5453.0
MAP1LC3B	3858.5	3812.5
MAP2K1	7852.0	3274.0
MAP2K2	-2882.5	-4769.5
MAP2K3	3494.0	-249.0
MAP2K4	2621.0	5572.0
MAP2K6	5640.0	-4115.0
MAP2K7	3505.0	-3383.0
MAPK1	-3928.0	6920.0
MAPK14	-6337.0	-1012.0
MAPK3	5390.0	5167.0
MAPK8	-3252.0	1695.0
MBD3	-3411.0	-3558.0
MC1R	583.0	7055.0
MC2R	2425.0	5288.0
MC3R	-1127.0	-884.0
MEFV	-4277.0	5186.0
MET	-7325.0	3597.0
MGAT1	-2205.0	-4578.0
MGAT2	-4100.0	4842.0
MGAT4A	8028.0	2426.0
MGAT4B	6084.0	-4137.0
MGAT4C	6273.0	-4542.0
MGAT5	-6087.0	2955.0
MNAT1	1928.0	4358.0
MOGS	-7081.0	-6077.0
MRC1	-5573.0	7131.0
MTA1	-1428.0	-2770.0
MTA2	-1000.0	4223.0
MTA3	3461.0	4368.0
MVB12A	5433.0	3851.0
MVB12B	-659.0	-5360.0
MYH9	7189.0	7115.0
MYO10	4745.0	-1478.0
MYO1C	7502.0	5436.0
MYO5A	-7077.0	3216.0
MYO9B	1982.0	-237.0
NCBP1	-6452.0	5580.0
NCBP2	-6814.0	136.0
NCK1	-4610.0	8438.0
NCKAP1	-5953.0	8521.0
NCKAP1L	-1592.0	4630.0
NCKIPSD	7238.0	-4983.0
NCOR1	-7262.0	6244.0
NCOR2	-225.0	-3484.0
NDC1	6665.0	-1084.0
NEDD4L	1323.0	-3476.0
NELFA	-3692.0	4383.0
NELFB	-4499.0	-5790.0
NELFCD	6086.0	1592.0
NELFE	-2178.0	4789.0
NFKB1	5449.0	4035.0
NFKB2	2120.0	-4751.0
NLRP3	-5337.0	1863.0
NMT1	-6059.0	6229.0
NMT2	2282.0	6516.0
NOS2	-1104.0	4079.0
NOX1	-145.0	1132.0
NOXO1	530.0	-4544.0
NR3C1	-2732.0	2240.0
NT5E	-7042.0	7643.0
NUP107	3423.0	7169.0
NUP133	2759.0	-4113.0
NUP153	-4638.0	7763.0
NUP155	6347.0	2192.0
NUP160	-5230.0	1753.0
NUP188	3880.0	-4145.0
NUP205	855.0	6303.0
NUP210	8193.0	-4172.0
NUP214	7802.0	-5326.0
NUP35	-4374.0	-921.0
NUP37	3596.0	1004.0
NUP42	4998.0	-596.0
NUP43	-2270.0	3764.0
NUP50	-4961.0	641.0
NUP54	-3355.0	6010.0
NUP58	2230.0	7116.0
NUP62	4963.0	-4765.0
NUP85	1103.0	-4750.0
NUP88	4817.0	4002.0
NUP93	5331.0	6196.0
NUP98	-2590.0	5122.0
P2RX4	7060.0	-4339.0
P2RX7	4651.0	4591.0
PACS1	7765.0	5342.0
PAK2	-4906.0	6708.0
PARP1	134.0	473.0
PARP10	7711.0	-4684.0
PARP14	-5054.0	4222.0
PARP16	1718.0	-2509.0
PARP4	6474.0	-716.0
PARP6	3375.0	4640.0
PARP8	-7014.0	-116.0
PARP9	-2628.0	513.0
PDCD1	-3283.0	5216.0
PDZD3	-5971.0	-5645.0
PGK1	-656.0	7226.0
PHF21A	-2368.0	829.0
PIK3C3	1518.0	-2612.0
PIK3R4	4272.0	-1214.0
PLCG1	8067.0	-4962.0
PLCG2	-5287.0	2474.0
PLK2	7974.0	8574.0
PML	6152.0	-5597.0
POLR2A	4937.0	-1941.0
POLR2B	-675.0	5037.0
POLR2C	2928.0	6859.0
POLR2D	-2762.0	6076.0
POLR2E	7128.0	-3504.0
POLR2F	6184.0	-3058.0
POLR2G	3306.0	-3566.0
POLR2H	4359.0	-4161.0
POLR2I	5890.0	6864.0
POLR2J	1742.0	3424.0
POLR2K	1098.0	7632.0
POLR2L	3697.0	-3808.0
POM121	3732.5	-6552.5
POM121C	3732.5	-6552.5
POMC	3685.0	-2222.0
PPIA	4868.0	-469.0
PRKACA	-530.0	15.0
PRKACB	569.0	661.0
PRKAR1A	3942.0	6647.0
PRKAR1B	6901.0	5113.0
PRKAR2A	5319.0	7462.0
PRKAR2B	-2382.0	-990.0
PRKCSH	-4469.0	-2597.0
PRKX	2536.5	8246.5
PSIP1	-6597.0	7229.0
PSMA1	-6705.0	7838.0
PSMA2	-5464.5	6058.5
PSMA3	-3145.0	7801.0
PSMA4	-6074.0	4688.0
PSMA5	-6660.0	4497.0
PSMA6	-1954.0	8445.0
PSMA7	1612.0	7052.0
PSMA8	649.0	-4004.0
PSMB1	-5281.0	5936.0
PSMB10	3752.0	-908.0
PSMB11	1977.0	-5501.0
PSMB2	1472.0	-4144.0
PSMB3	-3388.0	5539.0
PSMB4	-4941.0	-5852.0
PSMB5	-1638.0	-2409.0
PSMB6	1806.0	-1845.0
PSMB7	-4628.0	-657.0
PSMB8	1080.0	-3793.0
PSMB9	5987.0	-4708.0
PSMC1	-1312.0	4327.0
PSMC2	-6765.0	4648.0
PSMC3	-4285.0	3386.0
PSMC4	-6423.0	7920.0
PSMC5	-4831.0	1120.0
PSMC6	-6851.0	8666.0
PSMD1	-6497.0	8619.0
PSMD10	-1613.0	2576.0
PSMD11	-6873.0	5201.0
PSMD12	-6149.0	8628.0
PSMD13	1898.0	5044.0
PSMD14	-6080.0	8262.0
PSMD2	-6702.0	-3836.0
PSMD3	-2532.0	-3242.0
PSMD4	-5648.0	4994.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
PSMD7	-6943.0	7625.0
PSMD8	1978.0	7546.0
PSMD9	7707.5	-894.5
PSME1	2907.0	5905.0
PSME2	1270.0	-4595.0
PSME3	752.0	7366.0
PSME4	-6830.0	8511.0
PSMF1	5087.0	4771.0
PSTPIP1	-1224.0	-988.0
PTGDR	938.0	-1929.0
PTGER2	-614.0	-282.0
PTGER4	2504.0	1265.0
PTGES3	-7067.0	8733.0
PTGIR	-5223.0	4227.0
PTH1R	-5755.0	-4442.0
PTK2	2264.0	6997.0
PYCARD	6548.0	-4704.0
RAB5A	1537.0	7332.0
RAB7A	-5898.0	8083.0
RAC1	-1258.0	4008.0
RAE1	3041.0	-1934.0
RAMP1	-1058.0	6011.0
RAMP2	4827.0	-1533.0
RAMP3	-4098.0	6226.0
RAN	-4369.0	1437.0
RANBP1	-564.0	4423.0
RANBP2	-4575.0	8132.0
RANGAP1	-2328.0	-1549.0
RB1	7982.0	7013.0
RBBP4	-6148.0	5835.0
RBBP7	2154.0	6750.0
RBX1	-391.0	3201.0
RCC1	-3025.0	-5367.0
RCOR1	-6714.0	3288.0
RELA	2579.0	-2368.0
REST	3620.0	4343.0
RHBDF2	5334.0	-1261.0
RIPK1	-2977.0	5088.0
RLN2	2347.5	469.5
RNF213	-6529.0	-265.0
RNGTT	-3753.0	6441.0
RNMT	-3077.0	5647.0
ROCK1	-2765.0	8654.0
ROCK2	-1368.0	8738.0
RPL11	5748.0	1403.0
RPL12	6107.0	-5604.0
RPL13	5686.0	-3760.0
RPL14	5110.0	-1875.0
RPL18	2523.0	-625.0
RPL18A	4545.0	-3218.0
RPL19	4654.0	6782.0
RPL21	-1686.0	8463.0
RPL22	2365.0	459.0
RPL22L1	-5123.0	-6294.0
RPL23	-205.0	4253.0
RPL24	-409.0	6813.0
RPL26	3650.0	8722.0
RPL28	6714.0	4753.0
RPL29	2613.0	4628.0
RPL3	5378.0	1155.0
RPL30	4372.0	3664.0
RPL31	6732.0	-1507.0
RPL32	2989.0	8728.0
RPL34	661.0	7140.0
RPL35	5949.0	8834.0
RPL35A	-1509.0	6565.0
RPL36	7543.0	-2424.0
RPL36A	-5983.0	4837.0
RPL36AL	1793.0	-2074.0
RPL37	2109.0	-667.0
RPL38	5601.0	5675.0
RPL3L	-5986.0	4937.0
RPL4	2582.0	8471.0
RPL6	572.0	7594.0
RPL7	-5186.0	8598.0
RPL8	3526.0	820.0
RPLP2	3550.0	3555.0
RPN1	-7121.0	7464.0
RPN2	-5521.0	3974.0
RPS13	7174.0	315.0
RPS14	4070.0	4443.0
RPS15	7253.0	6174.0
RPS16	6244.0	1119.0
RPS17	5667.0	7685.0
RPS18	4253.0	-526.0
RPS19	6565.0	-1215.0
RPS2	7322.0	4216.0
RPS21	7111.0	-6494.0
RPS25	4261.0	8455.0
RPS27A	-133.0	-1807.0
RPS28	7208.0	-396.0
RPS3	2340.0	4381.0
RPS3A	-3115.0	8824.0
RPS4X	2522.0	7391.0
RPS5	3848.0	7515.0
RPS6	-1700.0	8603.0
RPS8	3874.0	7646.0
RPS9	-1719.0	-2555.0
RXFP1	-1082.0	-4426.0
S1PR1	4311.0	7637.0
SAP18	-2023.0	7183.0
SAP30	-6527.0	3941.0
SAP30L	-2917.0	-2070.0
SCTR	-219.0	-1332.0
SEC13	-1432.0	3604.0
SEH1L	2204.0	6910.0
SFPQ	-5196.0	-4828.0
SH3GL1	993.0	-4650.0
SH3GL2	-6503.0	867.0
SH3KBP1	3805.0	5866.0
SIGMAR1	178.0	-2004.0
SKP1	-6803.0	8394.0
SLC25A4	7196.0	-656.0
SLC25A5	7651.0	6887.0
SNF8	2397.0	-3270.0
SRC	-2657.0	-1643.0
SSRP1	2663.0	4754.0
ST3GAL1	3065.0	8669.0
ST3GAL2	6089.0	121.0
ST3GAL3	-3090.0	3648.0
ST3GAL4	-1264.0	1193.0
ST6GAL1	4830.0	6368.0
ST6GALNAC2	-6427.0	-3901.0
ST6GALNAC3	4083.0	6940.0
ST6GALNAC4	-365.0	4860.0
STAM	-2360.0	4932.0
STAM2	494.0	2564.0
STAT2	4437.0	-4922.0
STT3A	-6845.0	4709.0
STX1A	2774.0	-2559.0
STX1B	3559.0	374.0
SUDS3	2620.0	2169.0
SUGT1	3448.0	6681.0
SUMO1	-4690.0	8345.0
SUPT16H	-1751.0	7746.0
SUPT4H1	3573.0	2203.0
SUPT5H	5137.0	2571.0
SUZ12	-1028.0	8662.0
SV2A	6774.0	-1791.0
SV2C	-3739.0	-1283.0
SYK	-6921.0	4480.0
SYT1	-2989.0	-4969.0
SYT2	-2226.0	-4027.0
TAF1	-3038.5	3979.5
TAF10	-3030.0	2638.0
TAF11	3706.0	-6076.0
TAF12	-5685.0	2641.0
TAF13	-4258.0	1970.0
TAF15	-1144.0	2020.0
TAF1L	-3038.5	3979.5
TAF2	-5611.0	6188.0
TAF3	1245.0	3100.0
TAF4	2448.0	3472.0
TAF4B	6609.0	4831.0
TAF5	863.0	-388.0
TAF6	-2810.0	1885.0
TAF7	-5754.0	6658.0
TAF9	-3421.0	8678.0
TAF9B	-362.0	4853.0
TBK1	-5003.0	4897.0
TBL1X	-7106.5	7510.5
TBL1XR1	-1156.0	6145.0
TBP	3907.0	-217.0
TCEA1	-5628.0	8792.0
TGFB1	-1851.0	6152.0
TLR2	5407.0	5188.0
TLR7	-3743.0	5769.0
TLR9	-3935.5	846.5
TMPRSS2	7909.0	4409.0
TPR	-4239.0	8611.0
TRIM27	-452.0	-3380.0
TRIM28	-1390.0	-6154.0
TSG101	-708.0	7980.0
TSHB	5602.0	-4369.0
TSHR	3113.0	5679.0
TUBB	335.0	8036.0
TUSC3	-5686.0	4758.0
TXN	-5397.0	-2909.0
TXNIP	2986.0	4021.0
TXNRD1	-3425.0	4896.0
TYK2	3318.0	-6265.0
UBA52	7488.0	-4269.0
UBAP1	-6158.0	7653.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
UBE2I	5599.0	2810.0
UVRAG	-5823.0	-64.0
VAMP1	6428.0	-5633.0
VAMP2	8086.5	-3275.5
VAV1	-4395.0	5076.0
VAV2	2432.0	-843.0
VAV3	6942.0	5027.0
VCP	-7069.0	5449.0
VEGFA	-4619.0	-5156.0
VIPR1	776.0	8356.0
VIPR2	173.0	915.0
VPS25	-306.0	6834.0
VPS28	4871.0	5243.0
VPS33B	2918.5	-5911.5
VPS36	5728.0	8042.0
VPS37A	-5968.0	8308.0
VPS37B	5639.0	2161.0
VPS37C	5395.0	-224.0
VPS37D	-1556.0	-3123.0
VPS4A	-5731.5	7213.5
VPS4B	2398.0	6175.0
VTA1	-2777.0	104.0
WAS	-11.0	299.0
WASF1	-5233.0	-3651.0
WASF2	4804.0	1618.0
WASF3	4712.0	680.0
WASL	-3989.0	7855.0
WIPF1	-3718.0	7829.0
WIPF2	4034.0	-1247.0
WIPF3	7332.0	3435.0
WNT5A	5498.0	-739.0
XPO1	-6543.0	7447.0
XRCC4	-4715.0	7026.0
XRCC5	-2388.0	162.0
XRCC6	-1971.0	4034.0
YES1	-120.0	7265.0
ZBP1	-6151.0	4520.0
ZCRB1	3718.0	5429.0

---

---

G alpha (s) signalling events

G alpha (s) signalling events

metric	value
setSize	298
pMANOVA	1.03e-23
p.adjustMANOVA	4.83e-21
s.dist	0.31
s.diabetes	-0.168
s.mitoG	-0.261
p.diabetes	6.21e-07
p.mitoG	1.09e-14

Top 20 genes

Gene	diabetes	mitoG
OR10AG1	-6532.0	-6536.0
OR4C15	-5975.0	-6779.0
OR5B3	-5709.0	-6638.0
OR8G1	-5330.5	-6730.5
OR8G5	-5330.5	-6730.5
OR2AG1	-5383.5	-6588.5
OR2AG2	-5383.5	-6588.5
OR8K3	-5213.0	-6427.0
OR2T29	-5177.0	-6137.0
OR2T4	-5177.0	-6137.0
OR2T5	-5177.0	-6137.0
OR51Q1	-6613.0	-4520.0
OR10Q1	-4915.0	-6061.0
OR7D4	-4403.0	-6079.0
OR1F1	-4773.0	-5398.0
PTH1R	-5755.0	-4442.0
OR4A16	-3763.0	-6781.0
OR5AL1	-4425.0	-5493.0
OR6X1	-3559.0	-6602.0
OR4Q3	-3450.0	-6406.0

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
ADCY1	-4196.0	1876.0
ADCY2	5891.0	1358.0
ADCY3	-351.0	4656.0
ADCY4	-237.0	7618.0
ADCY5	2277.0	2395.0
ADCY6	7278.0	-6203.0
ADCY7	-5272.0	-2210.0
ADCY8	3778.0	-3880.0
ADCY9	2137.0	-5459.0
ADCYAP1	-2784.0	6784.0
ADCYAP1R1	6820.0	4772.0
ADM	7469.0	6606.0
ADM2	-2536.0	-3876.0
ADORA2A	-2349.0	1070.0
ADORA2B	-2957.0	819.0
ADRB1	5207.0	-4492.0
ADRB2	-6910.0	4340.0
ARRB1	-6250.0	3030.0
ARRB2	-3644.0	681.0
AVPR2	4980.0	2853.0
CALCA	-3485.0	-2743.0
CALCR	-2793.0	1335.0
CALCRL	-3264.0	8776.0
CRHR2	-903.0	2018.0
DRD1	-1465.0	4255.0
GHRHR	3635.0	3159.0
GLP1R	-3107.0	1309.0
GNAI1	-6368.0	8547.0
GNAI2	6737.0	5825.0
GNAI3	-3916.0	8277.0
GNAL	-869.0	2969.0
GNAS	-2825.0	5946.0
GNAZ	-1947.0	4122.0
GNB1	1685.0	7974.0
GNB2	5389.0	-1847.0
GNB4	-4648.0	2711.0
GNB5	4543.0	3032.0
GNG10	5845.0	2921.0
GNG11	-2960.0	5884.0
GNG12	-1212.0	6898.0
GNG2	4011.0	7569.0
GNG3	-1825.0	1443.0
GNG4	-653.0	-591.0
GNG5	-2879.0	-1254.0
GNG7	1904.0	-4062.0
GNG8	499.0	-762.0
GNGT1	1972.0	5695.0
GNGT2	-1053.0	5102.0
GPR176	-1437.0	7990.0
GPR20	-684.0	-2071.0
GPR27	-995.0	4679.0
GPR39	1163.0	-286.0
GRK2	-1123.0	7008.0
GRK3	-2167.0	-104.0
GRK5	280.0	5528.0
GRK6	6128.0	-4910.0
HRH2	-2405.0	714.0
LHCGR	-5643.5	-1575.5
MC1R	583.0	7055.0
MC2R	2425.0	5288.0
MC3R	-1127.0	-884.0
OR10A2	-1615.5	-5711.5
OR10A3	2457.5	-3360.5
OR10A5	-1615.5	-5711.5
OR10A6	2457.5	-3360.5
OR10A7	2712.0	-1349.0
OR10AD1	-3955.0	-4370.0
OR10AG1	-6532.0	-6536.0
OR10C1	-2872.0	3205.0
OR10D3	-2252.0	-350.0
OR10G6	-5705.0	-2209.0
OR10H1	-2606.0	-3818.0
OR10H2	-2606.0	-3818.0
OR10H3	-4761.5	-2534.5
OR10H4	-4761.5	-2534.5
OR10H5	-2606.0	-3818.0
OR10P1	-3736.0	277.0
OR10Q1	-4915.0	-6061.0
OR10S1	1731.0	-5614.0
OR10V1	0.0	789.0
OR10W1	1525.0	-3747.0
OR10X1	-1440.0	-245.0
OR11H7	-5063.0	-3296.0
OR11L1	-5319.0	131.0
OR12D3	2342.0	-5876.0
OR13C3	-1361.0	2376.0
OR13H1	-3614.0	-1722.0
OR13J1	2272.0	-3585.0
OR14C36	-3527.0	1868.0
OR14I1	2467.0	-3211.0
OR1A1	-3768.5	2904.5
OR1A2	-3768.5	2904.5
OR1B1	-1518.0	-4138.0
OR1F1	-4773.0	-5398.0
OR1I1	1108.0	-271.0
OR1N1	-547.0	-5999.0
OR1N2	-1054.0	-5518.0
OR2A12	-4300.0	-953.0
OR2A14	5466.0	-3634.0
OR2A4	-87.5	-1685.5
OR2A5	999.0	-5931.0
OR2A7	-87.5	-1685.5
OR2AG1	-5383.5	-6588.5
OR2AG2	-5383.5	-6588.5
OR2AK2	-1303.0	-3316.0
OR2AP1	1851.0	-3761.0
OR2B6	1764.0	-5241.0
OR2C1	-1818.0	-5150.0
OR2D2	-5314.0	-426.0
OR2D3	-2149.0	-1241.0
OR2F1	-1491.5	-516.5
OR2F2	-1491.5	-516.5
OR2H1	-2698.0	375.0
OR2H2	-3149.0	-5619.0
OR2J1	4584.0	-4421.0
OR2J2	4584.0	-4421.0
OR2J3	4584.0	-4421.0
OR2K2	-2010.0	1448.0
OR2L2	-3380.5	-1943.5
OR2L3	-3380.5	-1943.5
OR2L5	-3380.5	-1943.5
OR2L8	-3380.5	-1943.5
OR2T1	387.0	-4834.0
OR2T29	-5177.0	-6137.0
OR2T4	-5177.0	-6137.0
OR2T5	-5177.0	-6137.0
OR2T6	-3486.0	886.0
OR2V1	2357.0	-3628.0
OR2V2	3258.0	-2820.0
OR2W1	-887.0	-5117.0
OR2W3	3447.0	-5264.0
OR2Y1	520.0	-6783.0
OR4A16	-3763.0	-6781.0
OR4A47	-1039.0	2993.0
OR4A5	-4426.5	1579.5
OR4A8	-4426.5	1579.5
OR4B1	-596.0	-628.0
OR4C11	972.0	-5078.0
OR4C13	-2227.5	1176.5
OR4C15	-5975.0	-6779.0
OR4C16	-2196.0	365.0
OR4C3	-1427.0	343.0
OR4C45	-1978.0	-6021.0
OR4C46	-2227.5	1176.5
OR4C5	-1676.0	-6152.0
OR4D11	-254.0	-2572.0
OR4D2	904.0	-5776.0
OR4D5	2004.0	-1171.0
OR4D6	-4807.0	4102.0
OR4F15	3126.0	-5364.0
OR4F17	-1005.0	-5259.0
OR4F21	-3529.5	-498.5
OR4F3	-3529.5	-498.5
OR4F4	-1005.0	-5259.0
OR4F5	-1005.0	-5259.0
OR4F6	-2085.0	-5842.0
OR4K1	-2871.0	1777.0
OR4K15	-2336.0	2073.0
OR4K5	-3840.0	7563.0
OR4M1	1256.5	-4614.5
OR4M2	1256.5	-4614.5
OR4N4	-4652.0	1898.0
OR4P4	-2183.0	-5402.0
OR4Q3	-3450.0	-6406.0
OR4S2	-4538.0	-3613.0
OR4X2	-2257.0	-5505.0
OR51A7	-2353.0	4321.0
OR51B4	-2421.0	-2889.0
OR51E1	-892.0	3832.0
OR51E2	1389.0	-1746.0
OR51G1	789.0	-2341.0
OR51Q1	-6613.0	-4520.0
OR51S1	-2695.0	1245.0
OR51V1	3540.0	-5984.0
OR52A5	-2836.0	1656.0
OR52B2	-5034.0	4526.0
OR52D1	-5069.0	-3503.0
OR52E6	949.5	-6385.5
OR52E8	949.5	-6385.5
OR52H1	-1218.0	-6314.0
OR52I1	-13.5	2279.5
OR52I2	-13.5	2279.5
OR52K2	-2331.0	-5926.0
OR52M1	-2750.0	5676.0
OR52N2	-1282.0	-5772.0
OR56A3	1307.0	-424.0
OR56B2P	-763.0	-701.0
OR56B4	-4405.0	-660.0
OR5A1	1968.0	-3286.0
OR5A2	-1939.0	6129.0
OR5AC1	-3250.0	-1029.0
OR5AL1	-4425.0	-5493.0
OR5AN1	-2087.0	488.0
OR5AP2	1291.0	-6097.0
OR5B12	1509.0	-5462.0
OR5B3	-5709.0	-6638.0
OR5D14	-1767.0	-5389.0
OR5D18	-2307.0	-1013.0
OR5H1	2899.5	-1678.5
OR5H14	2899.5	-1678.5
OR5H15	2899.5	-1678.5
OR5H2	2899.5	-1678.5
OR5H6	2899.5	-1678.5
OR5I1	-595.0	-1801.0
OR5K1	1333.5	-6332.5
OR5K2	1333.5	-6332.5
OR5K3	6502.0	-4464.0
OR5L1	1271.5	-6716.5
OR5L2	1271.5	-6716.5
OR5M1	-587.5	-4801.5
OR5M10	-587.5	-4801.5
OR5M11	-4295.0	-2813.0
OR5M3	-7018.0	1713.0
OR5M9	-3581.5	1566.5
OR5P2	-1863.0	-6780.0
OR5V1	-1226.0	1270.0
OR5W2	-1650.0	-1270.0
OR6A2	-3361.0	3663.0
OR6B2	-24.5	-6012.5
OR6B3	-24.5	-6012.5
OR6C1	-4919.0	-2611.0
OR6C6	-654.0	-5957.0
OR6C65	4160.0	-3311.0
OR6C68	-2168.0	-1400.0
OR6C70	-727.0	-2396.0
OR6C76	-1452.0	-2198.0
OR6K2	-3420.0	-3849.0
OR6N2	-483.0	-3449.0
OR6S1	5654.0	-3043.0
OR6X1	-3559.0	-6602.0
OR6Y1	-3127.0	1731.0
OR7A10	1848.0	-4799.0
OR7A17	1848.0	-4799.0
OR7A5	1848.0	-4799.0
OR7C2	6881.0	-2433.0
OR7D4	-4403.0	-6079.0
OR7E24	-4864.0	4086.0
OR7G1	2812.0	-6343.0
OR7G2	2862.0	-36.0
OR8A1	-1173.0	-4925.0
OR8B2	-1568.5	-2264.5
OR8B3	-1568.5	-2264.5
OR8B8	-2771.0	1299.0
OR8G1	-5330.5	-6730.5
OR8G5	-5330.5	-6730.5
OR8H1	-1653.0	3580.0
OR8H2	-1653.0	3580.0
OR8H3	-1653.0	3580.0
OR8J1	-4734.5	5634.5
OR8J3	-4734.5	5634.5
OR8K3	-5213.0	-6427.0
OR8K5	-3684.0	-5439.0
OR8S1	1584.0	-4226.0
OR8U1	-536.0	-5955.0
OR9A1P	7476.0	-6030.0
OR9A2	2675.0	492.0
OR9A4	3554.0	-4308.0
OR9I1	2198.0	-4498.0
OR9K2	-5081.0	-2417.0
PDE10A	6281.0	672.0
PDE11A	-6545.0	894.0
PDE1A	-5021.0	5144.0
PDE1B	4499.0	-4026.0
PDE2A	3006.0	4319.0
PDE3A	-3429.0	8241.0
PDE3B	2729.0	6182.0
PDE4A	5345.0	1636.0
PDE4C	447.5	-6702.5
PDE4D	6616.0	3283.0
PDE7A	-3608.0	3002.0
PDE7B	6257.0	3440.0
PDE8A	-3329.0	7592.0
PDE8B	-3034.5	7876.5
POMC	3685.0	-2222.0
PTGDR	938.0	-1929.0
PTGER2	-614.0	-282.0
PTGER4	2504.0	1265.0
PTGIR	-5223.0	4227.0
PTH1R	-5755.0	-4442.0
RAMP1	-1058.0	6011.0
RAMP2	4827.0	-1533.0
RAMP3	-4098.0	6226.0
REEP1	-1074.0	-5002.0
REEP2	4.0	828.0
REEP3	-3229.0	6734.0
REEP4	3119.0	-2877.0
REEP5	-7146.0	3339.0
REEP6	8248.0	6316.0
RLN2	2347.5	469.5
RTP3	-4508.0	-2884.0
RTP4	-2887.0	3910.0
RXFP1	-1082.0	-4426.0
SCTR	-219.0	-1332.0
SRC	-2657.0	-1643.0
TSHB	5602.0	-4369.0
TSHR	3113.0	5679.0
VIPR1	776.0	8356.0
VIPR2	173.0	915.0

---

---

Metabolism of proteins

Metabolism of proteins

metric	value
setSize	1749
pMANOVA	2.08e-21
p.adjustMANOVA	7.29e-19
s.dist	0.153
s.diabetes	-0.0658
s.mitoG	0.138
p.diabetes	7.12e-06
p.mitoG	4.61e-21

Top 20 genes

Gene	diabetes	mitoG
HNRNPC	-7051	8787
CPE	-7351	8370
HSP90B1	-7279	8368
TOP1	-7160	8404
HSPA8	-7307	8180
PSMC6	-6851	8666
UBB	-7104	8341
CANX	-6936	8532
CAPZA1	-6942	8474
DNAJC3	-7149	8179
USO1	-6682	8749
PSME4	-6830	8511
CCT6A	-6594	8781
UBE2E1	-6831	8405
SKP1	-6803	8394
PDIA3	-7283	7821
TRAM1	-7037	8086
SUMO3	-7259	7825
PSMD1	-6497	8619
SSR1	-6752	8281

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
A4GNT	4195.0	1243.0
AAAS	5561.0	-2261.0
AARS1	-4867.0	5015.0
AARS2	-67.0	-1871.0
ABCA3	1074.0	-4546.0
ACADVL	-1391.0	91.0
ACE	-7162.0	-645.0
ACE2	8047.0	1319.0
ACHE	7193.0	2151.0
ACTB	-4152.0	7953.0
ACTL6A	523.0	2819.0
ACTR10	268.0	6666.0
ACTR1A	965.0	5035.0
ACTR5	5649.0	-5977.0
ACTR8	480.0	-4636.0
ADAM10	-6444.0	8149.0
ADAMTS1	-5452.0	8739.0
ADAMTS10	4075.0	-5365.0
ADAMTS12	3513.0	5824.0
ADAMTS13	676.0	3925.0
ADAMTS14	3645.0	-1429.0
ADAMTS15	-1865.0	-5976.0
ADAMTS16	6061.0	-5109.0
ADAMTS17	898.0	-2086.0
ADAMTS18	5565.0	-5223.0
ADAMTS19	-1084.0	3439.0
ADAMTS2	-2074.0	8088.0
ADAMTS3	5455.0	1208.0
ADAMTS4	-4558.0	7178.0
ADAMTS5	4732.0	6838.0
ADAMTS6	3714.0	2516.0
ADAMTS7	-3098.0	6102.0
ADAMTS8	3341.0	380.0
ADAMTS9	-4215.0	5871.0
ADAMTSL1	7394.0	7561.0
ADAMTSL2	1075.0	7367.0
ADAMTSL3	8145.0	-5509.0
ADAMTSL4	4218.0	4581.0
ADAMTSL5	4696.0	588.0
ADD1	-5137.0	969.0
ADGRF5	4138.0	8117.0
ADORA2A	-2349.0	1070.0
ADORA2B	-2957.0	819.0
ADRA2A	6239.0	-2148.0
ADRA2C	3959.0	-2881.0
ADRB2	-6910.0	4340.0
ADRM1	-6170.0	-477.0
AFP	7002.0	840.0
AGBL2	843.0	-1917.0
AGBL3	-1381.0	22.0
AGBL4	4738.0	-1532.0
AGBL5	1997.0	-5951.0
AGT	8188.0	618.0
AGTPBP1	-5932.0	5839.0
AIMP1	3483.0	-4465.0
AIMP2	3676.0	2367.0
ALB	6253.0	-380.0
ALG1	-2121.0	-4072.0
ALG10	-206.5	4755.5
ALG10B	-206.5	4755.5
ALG11	-1679.0	4323.0
ALG12	-3609.0	1483.0
ALG14	-5434.0	4618.0
ALG2	-6555.0	5827.0
ALG3	-509.0	-3892.0
ALG5	-3605.0	-1803.0
ALG6	706.0	-1870.0
ALG8	-6352.0	1201.0
ALG9	-2677.5	-938.5
ALPL	7672.0	1079.0
AMDHD2	-5012.5	-6718.5
AMELX	-2293.0	58.0
AMFR	6669.0	-1047.0
ANK1	-2384.0	4523.0
ANK2	6760.0	923.0
ANK3	-300.0	4794.0
ANKRD28	8017.0	7539.0
ANKRD9	7272.0	-4117.0
ANO8	7350.0	-5683.0
ANPEP	3600.0	1770.0
AOPEP	5930.0	-6631.0
AP3M1	-2721.0	8113.0
APC	4716.0	8376.0
APCS	-7048.0	4075.0
APEH	328.0	-4272.0
APH1A	5635.0	-6359.0
APH1B	7972.0	373.0
APLP2	6384.0	6357.0
APOA1	3682.0	-305.0
APOA2	5921.0	5590.0
APOA4	-3638.0	-1066.0
APOB	7604.0	5782.0
APOE	5835.0	342.0
APOL1	-5660.5	2701.5
APP	-5115.0	6758.0
AR	2841.0	2349.0
ARCN1	-6138.0	8768.0
ARF1	-5273.0	7470.0
ARF3	4831.5	-5103.5
ARF4	-6276.0	6071.0
ARF5	5403.0	222.0
ARFGAP1	-1727.0	-5894.0
ARFGAP2	5632.0	-3320.0
ARFGAP3	-1901.0	5934.0
ARFGEF2	5665.0	4322.0
ARL2	7475.0	-2736.0
ARRB1	-6250.0	3030.0
ARRB2	-3644.0	681.0
ARSA	4080.0	-2367.0
ARSB	-5231.0	2994.0
ARSG	-6486.0	-3133.0
ARSI	-5854.0	1182.0
ARSJ	-4150.0	1548.0
ARSK	-3950.0	5751.0
ART3	4663.0	4318.0
ART4	4588.0	8588.0
ASB1	5747.0	-5391.0
ASB11	8005.0	3354.0
ASB13	-4592.0	5233.0
ASB14	4009.0	1161.0
ASB15	2791.0	-2241.0
ASB16	-285.0	-261.0
ASB18	-1279.0	-1197.0
ASB2	-4035.0	3690.0
ASB3	-3110.0	1156.0
ASB4	2909.0	2350.0
ASB5	1025.0	-247.0
ASB6	2948.0	-2420.0
ASB7	4873.0	2631.0
ASB8	-2617.0	6851.0
ASB9	-6461.0	6880.0
ASGR1	4230.0	-1124.0
ASNS	419.0	3160.0
ASXL1	6731.0	-1061.0
ASXL2	2377.0	3074.0
ATF3	-845.0	6400.0
ATF4	-6143.0	7857.0
ATF6	-6191.0	8479.0
ATP6AP2	596.0	3605.0
ATP6V0D1	-3890.0	3817.0
ATXN3	633.5	4150.5
ATXN3L	633.5	4150.5
ATXN7	-353.0	-389.0
AURKA	514.0	6578.0
AURKAIP1	4765.0	3868.0
AURKB	4296.0	-837.0
AXIN1	2211.0	-3480.0
AXIN2	6079.0	1221.0
B2M	5339.0	4978.0
B3GALNT2	-6999.0	-4423.0
B3GLCT	2664.0	5363.0
B3GNT2	830.0	-6274.0
B3GNT3	-3777.0	7172.0
B3GNT4	1421.0	-968.0
B3GNT5	-1379.0	2480.0
B3GNT7	6328.0	-3498.0
B3GNT8	2914.0	-5528.0
B3GNT9	-141.0	2484.0
B3GNTL1	4655.0	-4657.0
B4GALT1	-356.0	-3621.0
B4GALT2	6215.0	627.0
B4GALT3	-1790.0	-3235.0
B4GALT4	6095.0	4039.0
B4GALT5	-7316.0	-2072.0
B4GALT6	-2315.0	8205.0
B4GAT1	7224.0	-6185.0
BABAM1	-4088.5	3864.5
BACE1	1099.0	3140.0
BAP1	891.0	3290.0
BARD1	16.0	-4000.0
BCHE	111.0	-2916.0
BCL10	-3598.0	5942.0
BET1L	2662.0	-5180.0
BGLAP	-4940.0	-647.0
BIRC2	-4230.0	3665.0
BIRC3	6091.0	6158.0
BIRC5	-3018.0	-2773.0
BLM	6861.0	5650.0
BMI1	-4453.5	8309.5
BMP15	6174.0	5215.0
BMP4	6672.0	7143.0
BRCA1	-2450.0	4279.0
BRCC3	-3707.0	8439.0
BST1	5884.0	6856.0
BTBD1	-5007.0	8727.0
BTBD6	2905.0	-1931.0
BTRC	3218.0	-5334.0
C1GALT1	-6844.0	7463.0
C1GALT1C1	-6956.0	8035.0
C3	7675.0	3404.0
C4A	-311.5	-5183.5
CALB1	8008.0	8105.0
CALCA	-3485.0	-2743.0
CALM1	-4401.0	8702.0
CALR	-7105.0	5809.0
CALU	-3535.0	8715.0
CAMKMT	-1114.0	1751.0
CAND1	-6336.0	3476.0
CANX	-6936.0	8532.0
CAPZA1	-6942.0	8474.0
CAPZA2	-1687.0	8135.0
CAPZB	-2513.0	7203.0
CARS1	-5829.0	185.0
CARS2	-4415.0	-4360.0
CASP8AP2	-4218.0	7406.0
CBX2	1808.0	-1479.0
CBX4	3352.0	-2144.0
CBX5	-2253.0	4533.0
CBX8	-2773.0	176.0
CCDC22	-4166.0	-3221.0
CCDC59	5464.0	1847.0
CCDC8	500.0	-661.0
CCL2	-1079.0	3167.0
CCNA2	4669.0	307.0
CCNE1	5096.0	360.0
CCNE2	2080.0	3324.0
CCNF	4264.0	-2470.0
CCP110	1823.0	739.0
CCT2	-5508.0	4188.0
CCT3	-6871.0	-215.0
CCT4	-4722.0	2145.0
CCT5	-6746.0	6513.0
CCT6A	-6594.0	8781.0
CCT6B	-5158.0	-3943.0
CCT7	-4755.0	5328.0
CCT8	-6214.0	2208.0
CD109	-5918.0	1745.0
CD52	-3982.0	3448.0
CD55	-6863.0	6749.0
CD59	5509.5	-1796.5
CDC20	6493.0	-3052.0
CDC25A	-5099.0	1807.0
CDC34	-806.0	2346.0
CDC73	-5482.0	8489.0
CDCA8	432.0	464.0
CDH2	-7013.0	-2104.0
CDK1	3873.0	2662.0
CEACAM5	3793.5	5357.5
CEACAM7	3793.5	5357.5
CEBPB	7403.0	754.0
CEBPG	-3135.0	6916.0
CES1	-7348.0	-6736.0
CETN2	-5912.0	7106.0
CFP	-3458.0	-5006.0
CFTR	-6902.0	4865.0
CHCHD1	122.0	7555.0
CHD3	-7230.0	-2465.0
CHM	-4490.0	8464.0
CHML	1162.0	5630.0
CHRDL1	-3595.0	4763.0
CHST10	-5839.0	-580.0
CHST8	6306.0	3826.0
CISH	-419.0	-2121.0
CKAP4	4629.0	6520.0
CLSPN	3534.0	-3857.0
CLTRN	-6828.5	7924.5
CMAS	-4436.0	2723.0
CNIH1	-3991.0	8144.0
CNIH2	-2187.0	-4202.0
CNIH3	282.0	-4450.0
CNTN3	1496.0	-2111.0
CNTN4	3084.0	-2922.0
CNTN5	-5428.0	-587.0
COG1	6605.0	-5589.0
COG2	549.0	4121.0
COG3	-5097.0	5605.0
COG4	1502.0	-5457.0
COG5	-2281.0	6788.0
COG6	-4517.0	730.0
COG7	6910.0	3017.0
COMMD1	-915.0	8837.0
COMMD10	4464.0	3207.0
COMMD2	1346.0	4984.0
COMMD3	-4289.0	8822.0
COMMD4	4990.0	-4771.0
COMMD5	-2686.0	-4351.0
COMMD6	-4712.0	-68.0
COMMD7	-5073.5	1534.5
COMMD8	-5016.0	752.0
COMMD9	-1892.0	-1552.0
COPA	488.0	2943.0
COPB1	-2848.0	7946.0
COPB2	-4259.0	8427.0
COPE	1600.0	4567.0
COPG1	-3891.0	3599.0
COPG2	2511.0	4641.0
COPS2	-5385.0	8716.0
COPS3	-904.0	8468.0
COPS4	-2811.0	8111.0
COPS5	430.0	6558.0
COPS6	1528.0	28.0
COPS7A	5878.0	-2436.0
COPS7B	-2394.0	-5916.0
COPS8	-147.0	1724.0
COPZ1	-4248.0	-67.0
COPZ2	3609.0	1137.0
CP	7736.0	7894.0
CPB2	7987.0	2813.0
CPE	-7351.0	8370.0
CPM	157.0	8264.0
CREB3	-3134.0	1357.0
CREB3L1	-6513.0	4189.0
CREB3L2	-2683.0	-4241.0
CREB3L3	5347.0	4219.0
CREB3L4	2995.0	530.0
CREBBP	-6181.0	3954.0
CREBRF	5014.0	2320.0
CRHR2	-903.0	2018.0
CSF1	-2451.0	7450.0
CSF2RA	-2892.0	-5044.0
CSF2RB	-5554.0	-817.0
CSNK1D	-1602.0	2506.0
CSNK2A1	-1453.5	2755.5
CSNK2A2	-2373.0	3684.0
CSNK2B	-3628.0	6622.0
CST3	2605.0	4686.0
CTBP1	2741.0	-5332.0
CTDSP2	6542.0	-3134.0
CTNNB1	-6022.0	2664.0
CTR9	-6522.0	7934.0
CTSA	6070.0	1611.0
CTSC	-1974.0	7696.0
CTSD	5035.5	6716.5
CTSH	-6661.0	6547.0
CTSZ	-2861.0	2478.0
CUL1	-2997.0	6875.0
CUL2	-6236.0	8506.0
CUL3	-3105.0	8488.0
CUL4A	1695.0	4740.0
CUL4B	-3340.0	8151.0
CUL5	-5371.0	8605.0
CUL7	7850.0	-5060.0
CUL9	5310.0	-5966.0
CXXC1	-2344.0	-23.0
CYLD	-4935.0	4060.0
DAD1	-601.0	-4283.0
DAG1	6646.0	3480.0
DAP3	7249.0	-2522.0
DARS1	-2473.0	7683.0
DARS2	-5166.0	329.0
DAXX	-867.0	1599.0
DCAF10	-6404.0	7363.0
DCAF11	2933.5	98.5
DCAF13	-6109.0	5418.0
DCAF17	-5679.0	335.0
DCAF4	6054.5	-1359.5
DCAF5	5719.0	1049.0
DCAF6	4193.0	4461.0
DCAF7	3398.0	-1866.0
DCAF8	32.0	-4825.0
DCP2	-4513.0	2966.0
DCTN1	7218.0	-3098.0
DCTN2	2623.0	-2017.0
DCTN3	-715.0	689.0
DCTN4	-4133.0	7527.0
DCTN5	-4033.0	5094.0
DCTN6	4374.0	7565.0
DCUN1D1	-5365.0	8421.0
DCUN1D2	-5235.0	979.0
DCUN1D3	-4742.0	2345.0
DCUN1D4	-1794.0	4516.0
DCUN1D5	-4561.0	3411.0
DDA1	4498.0	1487.0
DDB1	7351.0	4675.0
DDB2	7194.0	-3157.0
DDIT3	-2070.0	-609.0
DDOST	-5017.0	2674.0
DDX11	-1397.0	-4719.0
DDX17	-6389.0	-6574.0
DDX5	-3313.0	-2478.0
DDX58	7214.0	-485.0
DERL1	-5101.0	3639.0
DERL2	-7153.0	6854.0
DHDDS	-4632.0	-1973.0
DHPS	5170.0	-5001.0
DIS3	-6175.0	6931.0
DMP1	693.0	1827.0
DNAJB11	-7169.5	4919.5
DNAJB9	-6535.0	8004.0
DNAJC24	-3232.0	1312.0
DNAJC3	-7149.0	8179.0
DNMT1	-576.0	893.0
DNMT3A	-3125.0	-5315.0
DNMT3B	443.0	-468.0
DOHH	5309.0	-5875.0
DOLK	-1597.0	-6134.0
DOLPP1	4713.0	-4095.0
DPAGT1	-4124.0	-3201.0
DPH1	6675.0	-6022.0
DPH2	1888.0	-3053.0
DPH3	-1215.0	8198.0
DPH5	1726.0	-2410.0
DPH6	1352.0	7061.0
DPH7	6874.0	-3787.0
DPM1	4121.0	435.0
DPM2	4055.0	2348.0
DPM3	-20.0	-5789.0
DPP4	7258.0	6466.0
DTL	254.0	990.0
DYNC1H1	4822.0	2594.0
DYNC1I1	3045.0	-5230.0
DYNC1I2	-251.0	7398.0
DYNC1LI1	2249.0	7292.0
DYNC1LI2	-1436.0	1861.0
DYNLL1	-6952.0	7645.0
DYNLL2	4932.0	-5028.0
EARS2	-6504.0	-3209.0
EDEM1	-7256.0	285.0
EDEM2	-3522.0	-3508.0
EDEM3	-6042.0	5002.0
EEF1B2	1782.0	477.0
EEF1D	-4117.0	717.0
EEF1E1	-2005.5	5771.5
EEF1G	-4888.0	4247.0
EEF2	-3312.0	2063.0
EEF2KMT	4275.0	-1189.0
EID3	-1519.0	-3324.0
EIF2AK3	-6386.0	3372.0
EIF2B1	-777.0	6812.0
EIF2B2	614.0	1522.0
EIF2B3	5470.0	2436.0
EIF2B4	98.0	1851.0
EIF2B5	2161.0	3945.0
EIF2S1	-4830.0	8741.0
EIF2S2	-3307.0	8799.0
EIF2S3	-2819.5	4900.5
EIF3A	-4951.0	8381.0
EIF3B	-286.0	3875.0
EIF3C	4964.5	4995.5
EIF3D	511.0	8172.0
EIF3E	-4677.0	8580.0
EIF3F	2793.0	1790.0
EIF3G	836.0	1475.0
EIF3H	-4343.0	8629.0
EIF3I	5694.0	2343.0
EIF3J	-4890.0	8838.0
EIF3K	4728.0	6062.0
EIF3L	5174.0	4824.0
EIF3M	-2954.0	7258.0
EIF4A1	5335.0	61.0
EIF4A2	-6848.0	-699.0
EIF4B	-4266.0	-945.0
EIF4E	-4500.0	8429.0
EIF4EBP1	4976.0	3262.0
EIF4G1	-5996.0	5731.0
EIF4H	5370.0	-98.0
EIF5	-1683.0	7276.0
EIF5A	2123.5	2213.5
EIF5A2	170.0	5525.0
EIF5B	-1780.0	8616.0
ELOB	6643.0	3269.0
ELOC	-3325.0	7837.0
ENGASE	7650.0	-6005.0
ENPEP	7508.0	2528.0
EP300	-2449.0	1336.0
EPAS1	6886.0	8502.0
EPRS1	-5855.0	8062.0
ERAL1	2320.0	-4329.0
ERCC8	-1160.0	1435.0
ERN1	4698.0	-5209.0
ERO1A	3390.0	4892.0
ERO1B	-6862.0	6765.0
ESR1	-187.0	-1356.0
ETF1	-3268.0	8174.0
ETFB	5896.0	-2345.0
ETFBKMT	-1995.0	-1578.0
EVA1A	6345.0	-2797.0
EXOC1	-2979.0	-335.0
EXOC2	7117.0	-1912.0
EXOC3	-5362.0	5791.0
EXOC4	7198.0	5527.0
EXOC5	-2682.0	8595.0
EXOC6	-6197.0	3478.0
EXOC7	2029.0	3647.0
EXOC8	-1501.0	-3511.0
EXOSC1	-2448.0	7613.0
EXOSC2	3957.0	3800.0
EXOSC3	-1469.0	-3935.0
EXOSC4	-3182.0	-4923.0
EXOSC5	4223.0	-3378.0
EXOSC7	6973.0	-5606.0
EXOSC8	6788.0	616.0
EXOSC9	4661.0	7068.0
EXTL1	7674.0	-2378.0
EXTL2	7432.0	5309.0
EXTL3	-746.0	6502.0
F10	7628.0	-1082.0
F2	-3087.0	4699.0
F5	-5716.0	-1378.0
F7	2284.0	-3692.0
F8	-688.0	7499.0
FAM20A	4604.0	5067.0
FAM20C	-6640.0	-3728.0
FARS2	-83.0	-1983.0
FARSA	-2969.0	-5485.0
FARSB	-6744.0	5894.0
FAU	6809.0	7710.0
FBN1	6578.0	8391.0
FBXL12	6303.0	-6457.0
FBXL13	1597.0	-4376.0
FBXL14	3254.0	-5925.0
FBXL15	4607.0	-4358.0
FBXL16	4642.0	451.0
FBXL18	3324.0	-4163.0
FBXL19	-1608.0	-4038.0
FBXL20	3692.0	-5654.0
FBXL22	5538.0	-6092.0
FBXL3	-5113.0	5030.0
FBXL4	3694.0	2851.0
FBXL5	-5339.0	1379.0
FBXL7	-3047.0	1531.0
FBXL8	1855.5	-6099.5
FBXO10	-2534.0	-4069.0
FBXO11	-2703.0	8171.0
FBXO15	-1975.0	2890.0
FBXO17	3510.0	-1954.0
FBXO2	4620.0	4693.0
FBXO21	8209.0	-5962.0
FBXO22	-6695.0	4983.0
FBXO27	-2654.0	1841.0
FBXO30	-5216.0	5730.0
FBXO31	5477.0	-4217.0
FBXO32	7523.0	2250.0
FBXO4	-5534.0	5796.0
FBXO40	-4210.0	4616.0
FBXO6	7480.0	1442.0
FBXO7	-6524.0	-2660.0
FBXO9	-3297.0	-3812.0
FBXW10	-457.0	-3065.0
FBXW11	-3788.0	3125.0
FBXW12	858.0	-1111.0
FBXW2	2426.0	1249.0
FBXW4	6455.0	-3779.0
FBXW5	6633.0	-4037.0
FBXW7	-1739.0	4510.0
FBXW8	7356.0	-1698.0
FBXW9	7633.0	-5232.0
FCGR3B	-5407.5	6212.5
FCSK	7695.0	-6539.0
FEM1A	-503.0	-4374.0
FEM1B	-180.0	4328.0
FEM1C	-3374.0	4793.0
FFAR1	-5105.0	-4068.0
FFAR4	585.0	-487.0
FGA	4508.0	5893.0
FGG	5980.0	5427.0
FKBP14	4931.0	2750.0
FKBP8	1589.0	-3343.0
FKBP9	-5539.0	3811.0
FN1	7489.0	8379.0
FN3K	-3679.0	-6554.0
FN3KRP	798.0	-502.0
FOLR1	-6908.0	-283.0
FOLR2	4808.5	-5490.5
FOXK1	3482.0	-6464.0
FOXK2	-5706.0	1999.0
FOXO4	257.0	-4431.0
FPGT	-6295.0	6525.0
FSTL1	4528.0	8707.0
FSTL3	7808.0	-4121.0
FUCA1	-2319.0	5869.0
FUCA2	-6780.0	1532.0
FUOM	4551.0	-917.0
FURIN	3696.0	-3590.0
FUT8	-5026.0	4575.0
GADD45GIP1	-3733.0	2788.0
GALNT1	-6827.0	6806.0
GALNT10	2250.0	7699.0
GALNT11	-38.0	-3955.0
GALNT12	6172.0	-2979.0
GALNT13	-1133.0	-4324.0
GALNT14	-7194.0	-1930.0
GALNT15	6847.0	5369.0
GALNT16	1150.0	-4717.0
GALNT17	-5790.0	5548.0
GALNT18	-4976.0	1906.0
GALNT2	-4331.0	2581.0
GALNT3	-6728.0	6831.0
GALNT4	4213.5	-1901.5
GALNT6	538.0	-3543.0
GALNT7	-5139.0	1034.0
GALNT9	3166.0	-4823.0
GALNTL6	1986.0	-5583.0
GAN	7738.0	-2732.0
GANAB	-6749.0	-2365.0
GAPDHS	-249.0	-6258.0
GARS1	4295.0	8223.0
GAS6	7430.0	-2362.0
GATA3	7885.0	-1653.0
GATA4	-2965.0	622.0
GATA6	-1651.0	6694.0
GBA	-5712.0	-3677.0
GBF1	-6681.0	3356.0
GCNT1	-6421.0	-331.0
GCNT3	4031.0	-5990.0
GCNT4	7870.0	5943.0
GCNT7	4911.0	-6391.0
GFM1	-5522.0	6232.0
GFM2	-6515.0	123.0
GFPT1	-5236.0	4132.0
GFPT2	1399.0	5662.0
GGA1	-539.0	-4988.0
GGA2	2677.0	-3451.0
GGA3	-3482.0	-6019.0
GGCX	-6750.0	-4579.0
GHRL	2424.0	-6123.0
GLB1	-5376.0	2645.0
GMDS	3172.0	2992.0
GMPPA	-3878.0	-1263.0
GMPPB	-3902.0	-4795.0
GNAI1	-6368.0	8547.0
GNAI2	6737.0	5825.0
GNAI3	-3916.0	8277.0
GNAO1	-2148.0	5346.0
GNAT1	6189.0	2321.0
GNAT2	3267.0	-3915.0
GNAZ	-1947.0	4122.0
GNB1	1685.0	7974.0
GNB2	5389.0	-1847.0
GNB4	-4648.0	2711.0
GNB5	4543.0	3032.0
GNE	5717.0	4001.0
GNG10	5845.0	2921.0
GNG11	-2960.0	5884.0
GNG12	-1212.0	6898.0
GNG2	4011.0	7569.0
GNG3	-1825.0	1443.0
GNG4	-653.0	-591.0
GNG5	-2879.0	-1254.0
GNG7	1904.0	-4062.0
GNG8	499.0	-762.0
GNGT1	1972.0	5695.0
GNGT2	-1053.0	5102.0
GNPNAT1	66.0	8335.0
GOLGB1	-4541.0	3630.0
GOLM1	7444.0	4859.0
GORASP1	1404.0	-5586.0
GOSR1	2520.0	5197.0
GOSR2	-4613.5	7118.5
GP2	-1211.0	-3807.0
GPAA1	696.0	-5319.0
GPC3	-3602.0	6611.0
GPIHBP1	4244.0	8224.0
GPLD1	1497.0	-753.0
GPS1	-1275.0	3233.0
GRIA1	3840.0	-983.0
GSK3A	3838.0	1447.0
GSN	7535.0	7997.0
GSPT1	-6653.0	8055.0
GSPT2	-1500.0	-264.0
H2AC20	7413.0	2470.0
H2AC21	6478.0	633.0
H2AW	-5259.0	4003.0
H2AZ1	-980.0	4206.0
H2BC11	3900.0	-3127.0
H2BC14	1703.0	1613.0
H2BC18	4839.0	6098.0
H2BC5	3445.0	-761.0
H3-3A	-1695.0	7826.0
H3C15	7988.0	2080.0
HARS1	740.0	3109.0
HARS2	-3395.0	-2849.0
HCFC1	-1575.0	1730.0
HDAC1	-3050.0	4701.0
HDAC2	-6396.0	8620.0
HDAC3	5142.0	-772.0
HDAC4	3270.0	-868.0
HDAC7	5870.0	-2839.0
HDGF	-5612.0	7365.0
HERC2	-123.0	-4460.0
HERPUD1	924.0	3108.0
HGS	-1920.0	704.0
HIC1	1899.0	3532.0
HIF1A	7374.0	8562.0
HIF3A	5098.0	-246.0
HIPK2	-2011.0	3610.0
HLTF	-7039.0	7617.0
HNRNPC	-7051.0	8787.0
HNRNPK	-808.0	7246.0
HRC	276.0	-2090.0
HSP90B1	-7279.0	8368.0
HSPA5	-7309.0	7589.0
HSPA8	-7307.0	8180.0
HSPG2	5843.0	5956.0
HYOU1	-7255.0	4009.0
IARS1	-5409.0	3400.0
IARS2	-3392.0	319.0
ICMT	-315.0	-1207.0
IDE	-1263.0	3492.0
IFIH1	-1353.0	5986.0
IGF1	-6185.0	5101.0
IGF2	-4212.0	5578.0
IGFALS	5857.0	-6286.0
IGFBP1	4095.0	5747.0
IGFBP2	3766.0	-1385.0
IGFBP3	2259.0	8596.0
IGFBP4	-3451.0	-5136.0
IGFBP5	-3193.0	3366.0
IGFBP6	546.0	237.0
IGFBP7	-655.0	-4154.0
IKBKE	2587.0	-6365.0
IKBKG	3700.0	-677.0
IL33	7328.0	7911.0
INCENP	-473.0	3252.0
ING2	-3962.0	7754.0
INHA	5991.0	-2589.0
INHBA	-3201.0	3614.0
INHBB	422.0	5655.0
INHBE	2408.0	-5811.0
INO80	4038.0	3998.0
INO80B	6545.5	-3302.5
INO80C	4335.0	3546.0
INO80D	-6575.0	6230.0
INO80E	-899.0	1705.0
ITIH2	-3802.0	562.0
ITM2B	7419.0	4881.0
JOSD1	-6550.0	274.0
JOSD2	-6887.0	-5777.0
KARS1	3885.0	5716.0
KAT2A	-3442.0	-2675.0
KAT2B	-5780.0	6796.0
KBTBD13	2313.0	2189.0
KBTBD6	-6874.5	7477.5
KBTBD7	-6874.5	7477.5
KBTBD8	-2145.0	-505.0
KCTD6	5371.0	1842.0
KCTD7	3938.0	-338.0
KDELR1	-5082.0	-3141.0
KDELR2	-4969.0	8520.0
KDELR3	3008.0	2539.0
KDM1B	-5262.0	5818.0
KEAP1	-3703.0	-3144.0
KHSRP	-2184.0	-6452.0
KIF13A	6915.0	140.0
KIF5A	-5260.0	-5278.0
KIF5B	-1547.0	8819.0
KIF5C	6290.0	2117.0
KIFC3	4280.0	-3964.0
KIN	1226.0	3114.0
KLF4	5830.0	7414.0
KLHDC3	5826.0	-5495.0
KLHL11	4250.0	3553.0
KLHL13	-3686.0	6045.0
KLHL2	-6669.0	8214.0
KLHL20	-3947.0	1875.0
KLHL21	7522.0	-6646.0
KLHL22	-810.5	-5052.5
KLHL25	823.0	-4743.0
KLHL3	6109.0	2377.0
KLHL41	5118.0	-6151.0
KLHL42	-111.0	-2648.0
KLHL5	4270.0	3505.0
KLHL9	-5268.0	6137.0
KLK1	7226.0	8842.0
KLK2	7226.0	8842.0
KLK3	7226.0	8842.0
KNG1	7980.0	7099.0
KTN1	8011.0	6420.0
L3MBTL2	4709.0	-804.0
LAMB1	1484.0	-2565.0
LAMB2	7370.0	6700.0
LAMC1	7625.0	6528.0
LARGE1	1668.0	1564.0
LARGE2	7616.0	-196.0
LARS1	7823.0	-1599.0
LARS2	6811.0	-3357.0
LEO1	-7109.0	5081.0
LGALS1	5562.0	3929.0
LMAN1	-4772.0	8101.0
LMAN2	-6960.0	209.0
LMAN2L	-6950.0	-4458.0
LMCD1	-143.0	4522.0
LMNA	5092.0	-3667.0
LMO7	6730.0	-2505.0
LONP2	-2509.0	2136.0
LRRC41	907.0	-3596.0
LRRC49	6677.0	-1028.0
LSAMP	3143.0	-1218.0
LTBP1	-5412.0	7176.0
LTF	-2111.0	1638.0
LY6D	-5266.0	-2235.0
LY6E	-7355.0	5208.0
LY6G6C	4541.0	-5396.0
LY6G6D	4861.0	-2442.0
LY6H	2837.0	-6470.0
LYPD1	-1870.0	744.0
LYPD5	-2471.0	-1799.0
LYPD6B	250.0	6073.0
MAGT1	-6822.0	7703.0
MAN1A1	-4332.0	3367.0
MAN1A2	-1067.0	6604.0
MAN1B1	-1873.0	-6055.0
MAN1C1	6879.0	7174.0
MAN2A1	8162.0	5453.0
MAN2A2	-1276.0	3170.0
MANEA	6645.0	7410.0
MAP3K7	1594.0	7480.0
MARCHF6	3309.0	-3001.0
MARS1	-1343.0	1975.0
MARS2	-1273.0	3903.0
MAT2B	4842.0	-1317.0
MAVS	6937.0	-2375.0
MBD1	-29.0	2332.0
MBD5	-1298.0	-5280.0
MBD6	2343.0	-6676.0
MBOAT4	418.0	-5343.0
MBTPS1	-6525.0	-4354.0
MBTPS2	5009.0	5876.0
MCFD2	-4954.0	6881.0
MCRS1	3404.0	504.0
MDC1	2939.0	-2511.0
MDGA1	-2378.0	-2911.0
MDGA2	-773.0	-2625.0
MDM2	5569.0	7967.0
MDM4	-2223.0	-5305.0
MELTF	-15.0	-1729.0
MEN1	-1596.0	-513.0
METTL21A	1969.0	-2314.0
METTL22	7110.0	-3618.0
MFGE8	7259.0	7979.0
MGAT1	-2205.0	-4578.0
MGAT2	-4100.0	4842.0
MGAT3	-6706.0	-3427.0
MGAT4A	8028.0	2426.0
MGAT4B	6084.0	-4137.0
MGAT4C	6273.0	-4542.0
MGAT5	-6087.0	2955.0
MIA2	-5486.0	8570.0
MITF	4134.0	-1967.0
MLEC	-7059.0	-620.0
MME	-2831.0	3783.0
MMP2	1375.0	7816.0
MOGS	-7081.0	-6077.0
MPDU1	3608.0	-2985.0
MPI	-1157.0	6001.0
MRPL1	1286.0	8159.0
MRPL10	-1416.0	3188.0
MRPL11	3808.0	6016.0
MRPL12	-2913.0	4144.0
MRPL13	-2133.0	8018.0
MRPL14	5767.0	-2010.0
MRPL15	-1507.0	6146.0
MRPL16	-3432.0	6832.0
MRPL17	-3013.0	6746.0
MRPL18	-4156.0	1438.0
MRPL19	-3194.0	2428.0
MRPL2	5055.0	-5149.0
MRPL20	1293.0	4469.0
MRPL21	-799.0	2412.0
MRPL22	-5154.0	-1134.0
MRPL23	4418.5	-1265.5
MRPL24	167.0	-5286.0
MRPL27	6178.0	223.0
MRPL28	-814.0	3971.0
MRPL3	-5665.0	5800.0
MRPL30	5279.5	6918.5
MRPL32	-3800.0	8800.0
MRPL33	4456.0	7014.0
MRPL34	-2475.0	4196.0
MRPL35	-1990.0	4213.0
MRPL36	-5899.0	-1881.0
MRPL37	1624.0	-2298.0
MRPL38	-1580.0	-1874.0
MRPL39	-3794.0	7408.0
MRPL4	2533.0	-622.0
MRPL40	1526.0	8099.0
MRPL41	545.0	8072.0
MRPL42	-5566.0	8289.0
MRPL43	-3342.0	5014.0
MRPL44	-5549.0	3692.0
MRPL45	-4657.0	6949.0
MRPL46	-1481.0	2016.0
MRPL47	-173.0	6333.0
MRPL48	4560.0	-1377.0
MRPL49	-3192.0	2142.0
MRPL50	-6689.0	2066.0
MRPL51	-2846.0	4410.0
MRPL52	2165.0	-3073.0
MRPL53	2825.0	3497.0
MRPL54	5396.0	907.0
MRPL55	5095.0	1320.0
MRPL57	2949.0	3506.0
MRPL58	-1976.0	8348.0
MRPL9	-352.0	-3556.0
MRPS10	4929.0	5018.0
MRPS11	2555.0	585.0
MRPS12	-4229.0	-800.0
MRPS14	258.0	-5974.0
MRPS15	2010.0	4604.0
MRPS16	6603.0	-4108.0
MRPS17	1394.5	3322.5
MRPS18A	-1096.0	6572.0
MRPS18B	4074.0	7739.0
MRPS18C	6179.0	-533.0
MRPS2	-5787.0	3563.0
MRPS21	-3010.0	2159.0
MRPS22	-6062.0	5844.0
MRPS23	2764.0	7713.0
MRPS24	3458.0	-4271.0
MRPS25	4256.0	-52.0
MRPS26	2737.0	-3789.0
MRPS27	-2609.0	6487.0
MRPS28	1938.0	-3683.0
MRPS30	-1214.0	5020.0
MRPS31	-818.0	6947.0
MRPS33	-3942.0	3752.0
MRPS34	2549.0	1835.0
MRPS35	407.0	4566.0
MRPS36	-5930.0	3441.0
MRPS5	1465.0	6.0
MRPS6	5713.0	5000.0
MRPS7	-5350.0	4087.0
MRPS9	6568.0	2476.0
MRRF	-4590.0	6519.0
MRTFA	-4911.0	-662.0
MSLN	-1618.0	3678.0
MSRA	3771.0	2953.0
MSRB1	-6225.0	6397.0
MSRB2	-4656.0	-1148.0
MSRB3	-2086.0	8826.0
MTA1	-1428.0	-2770.0
MTFMT	-3002.0	-2497.0
MTIF2	-5952.0	6049.0
MTIF3	-4042.0	3794.0
MTRF1L	-4995.0	-1737.0
MUC1	7970.0	3179.0
MUC13	3695.0	1168.0
MUC19	-1591.0	-6413.0
MUC20	3931.0	5255.0
MUC3A	4383.0	638.0
MUC4	-846.0	-343.0
MUC5B	1330.0	-4558.0
MUC6	3660.0	-6706.0
MUL1	6223.0	-5611.0
MVD	-6321.0	-3670.0
MXRA8	-35.0	8623.0
MYC	1892.0	3123.0
MYDGF	-5990.0	2852.0
MYO5A	-7077.0	3216.0
MYRIP	7420.0	4392.0
MYSM1	2209.0	5254.0
N6AMT1	6423.0	2373.0
NAE1	-3040.0	7552.0
NAGK	-4604.0	-6000.0
NANP	6116.0	213.0
NANS	-6265.0	4736.0
NAPA	5425.0	1632.0
NAPB	2953.0	-4029.0
NAPG	3323.0	2180.0
NAPSA	-1716.0	-1187.0
NARS1	-2358.0	7860.0
NARS2	-703.0	-3681.0
NAT8	5416.5	-6545.5
NAT8B	5416.5	-6545.5
NCOA1	-3434.0	7005.0
NCOA2	-5757.0	5994.0
NCOR2	-225.0	-3484.0
NCSTN	6534.0	860.0
NDC1	6665.0	-1084.0
NEDD8	-4578.0	7681.0
NEGR1	605.0	6193.0
NEU1	-4896.0	-6581.0
NEU2	-5135.0	4638.0
NEU3	5534.0	4644.0
NEURL2	6233.0	-6698.0
NFKB2	2120.0	-4751.0
NFKBIA	1631.0	4830.0
NFRKB	6706.0	-4434.0
NFYA	-6056.0	1269.0
NFYB	4475.0	-1375.0
NFYC	5234.0	-4754.0
NGLY1	-6176.0	6210.0
NICN1	6266.5	2603.5
NLRP3	-5337.0	1863.0
NOD1	5283.0	4068.0
NOD2	-6286.0	2681.0
NOP56	-875.0	1129.0
NOP58	-4438.0	5964.0
NOTUM	-4518.0	-4347.0
NPL	7879.0	2302.0
NR1H2	3611.0	-4559.0
NR1H3	-6285.0	1226.0
NR1H4	6851.0	5380.0
NR1I2	2434.0	-4905.0
NR2C1	-431.0	2786.0
NR3C1	-2732.0	2240.0
NR3C2	7008.0	-3900.0
NR4A2	-168.0	5972.0
NR5A2	-2631.0	-1601.0
NRIP1	-4907.0	6136.0
NRN1	2297.0	1476.0
NSF	4215.0	7420.0
NSMCE1	6895.0	-3356.0
NSMCE2	5776.0	-3866.0
NSMCE3	2746.0	-3003.0
NSMCE4A	5303.0	6438.0
NTM	3762.0	317.0
NTNG1	-6397.0	4061.0
NTNG2	4666.0	-4040.0
NUB1	7499.0	664.0
NUCB1	-4766.0	6164.0
NUDT14	1773.0	5977.0
NUP107	3423.0	7169.0
NUP133	2759.0	-4113.0
NUP153	-4638.0	7763.0
NUP155	6347.0	2192.0
NUP160	-5230.0	1753.0
NUP188	3880.0	-4145.0
NUP205	855.0	6303.0
NUP210	8193.0	-4172.0
NUP214	7802.0	-5326.0
NUP35	-4374.0	-921.0
NUP37	3596.0	1004.0
NUP42	4998.0	-596.0
NUP43	-2270.0	3764.0
NUP50	-4961.0	641.0
NUP54	-3355.0	6010.0
NUP58	2230.0	7116.0
NUP62	4963.0	-4765.0
NUP85	1103.0	-4750.0
NUP88	4817.0	4002.0
NUP93	5331.0	6196.0
NUP98	-2590.0	5122.0
NUS1	-3128.0	2669.0
OBSL1	-2821.0	4269.0
OGT	-4547.0	-6169.0
OPCML	-1744.0	-2172.0
OS9	-5615.0	3279.0
OTOA	1547.0	-1720.0
OTUB1	3275.0	3588.0
OTUB2	-4667.0	-3379.0
OTUD3	-2182.0	-768.0
OTUD5	-963.0	-1531.0
OTUD7A	-562.0	1361.0
OTUD7B	3158.0	927.0
OTULIN	-2347.0	4384.0
OXA1L	4609.0	-4940.0
P2RY2	7810.0	1570.0
P4HB	-6743.0	5398.0
PABPC1	-949.0	6861.0
PAF1	799.0	4723.0
PAPPA	7511.0	6087.0
PAPPA2	-6969.0	-6456.0
PARK7	-4866.0	231.0
PARN	7135.0	-1655.0
PARP1	134.0	473.0
PARS2	2925.0	-4066.0
PAX6	-2974.0	1272.0
PCGF2	6981.0	-1609.0
PCMT1	766.0	5209.0
PCNA	5956.0	8353.0
PCSK2	-329.0	-3823.0
PCSK9	38.0	1779.0
PDCL	-1384.0	7789.0
PDIA3	-7283.0	7821.0
PDIA5	-7010.0	3584.0
PDIA6	-7267.0	3608.0
PENK	3856.0	1044.0
PEX10	4740.0	-3790.0
PEX12	3372.0	1451.0
PEX13	-1588.0	5391.0
PEX14	5317.0	5271.0
PEX2	-6638.0	5954.0
PEX5	4872.0	-5747.0
PFDN1	-3515.0	485.0
PFDN2	-1073.0	7198.0
PFDN4	-210.0	3562.0
PFDN5	2482.0	8089.0
PFDN6	2162.0	-2593.0
PGAP1	3191.0	1054.0
PGM3	-5155.0	-58.0
PGR	-4247.0	5891.0
PHC1	-3375.0	-2631.0
PHC2	4373.0	-2023.0
PHC3	-3667.0	-4511.0
PIAS1	3194.0	2440.0
PIAS2	-551.0	4275.0
PIAS3	5881.0	-5095.0
PIAS4	1983.0	-5993.0
PIGA	5537.0	-3293.0
PIGB	-2545.0	-3897.0
PIGC	-712.0	-1136.0
PIGF	-358.0	4560.0
PIGG	481.0	5219.0
PIGH	-4713.0	4084.0
PIGK	-5555.0	7969.0
PIGL	2370.0	-566.0
PIGM	6207.0	-1731.0
PIGN	-3685.0	-6029.0
PIGO	2497.0	-6067.0
PIGP	-982.0	4138.0
PIGQ	-2789.0	-1693.0
PIGS	7634.0	-6215.0
PIGT	2201.0	-3364.0
PIGU	-128.0	-4230.0
PIGV	-5167.0	-5907.0
PIGW	3382.0	-3016.0
PIGX	-1642.0	7181.0
PIGY	6362.0	-5350.0
PLA2G4B	-2563.5	-6753.5
PLA2G7	1166.0	4921.0
PLAUR	4004.0	6827.0
PLET1	2119.0	3517.0
PLG	1632.0	-1603.0
PML	6152.0	-5597.0
PMM1	7751.0	-3527.0
PMM2	-447.0	-333.0
PNPLA2	7942.0	833.0
POFUT2	2819.0	2567.0
POLB	-5395.0	7452.0
POM121	3732.5	-6552.5
POM121C	3732.5	-6552.5
POMC	3685.0	-2222.0
POMGNT1	-1550.0	1400.0
POMGNT2	-477.0	-4638.0
POMK	-3654.0	738.0
POMT1	5670.0	-6064.0
POMT2	-591.0	-5247.0
PPA1	4412.0	6506.0
PPA2	-5134.0	6061.0
PPARA	7841.0	-6419.0
PPARG	-3636.0	5654.0
PPARGC1A	7867.0	2494.0
PPP2R5B	627.0	5414.0
PPP6C	1874.0	5889.0
PPP6R1	-4706.0	-2647.0
PPP6R3	-5114.0	7597.0
PREB	-6991.0	-1923.0
PRKCSH	-4469.0	-2597.0
PRKDC	-5092.0	3381.0
PRMT3	1957.0	-2306.0
PRND	1920.0	1499.0
PROS1	4907.0	7279.0
PROZ	-386.0	-4681.0
PRSS23	-4729.0	8268.0
PSCA	3876.0	-2120.0
PSENEN	-3656.0	5812.0
PSMA1	-6705.0	7838.0
PSMA2	-5464.5	6058.5
PSMA3	-3145.0	7801.0
PSMA4	-6074.0	4688.0
PSMA5	-6660.0	4497.0
PSMA6	-1954.0	8445.0
PSMA7	1612.0	7052.0
PSMA8	649.0	-4004.0
PSMB1	-5281.0	5936.0
PSMB10	3752.0	-908.0
PSMB11	1977.0	-5501.0
PSMB2	1472.0	-4144.0
PSMB3	-3388.0	5539.0
PSMB4	-4941.0	-5852.0
PSMB5	-1638.0	-2409.0
PSMB6	1806.0	-1845.0
PSMB7	-4628.0	-657.0
PSMB8	1080.0	-3793.0
PSMB9	5987.0	-4708.0
PSMC1	-1312.0	4327.0
PSMC2	-6765.0	4648.0
PSMC3	-4285.0	3386.0
PSMC4	-6423.0	7920.0
PSMC5	-4831.0	1120.0
PSMC6	-6851.0	8666.0
PSMD1	-6497.0	8619.0
PSMD10	-1613.0	2576.0
PSMD11	-6873.0	5201.0
PSMD12	-6149.0	8628.0
PSMD13	1898.0	5044.0
PSMD14	-6080.0	8262.0
PSMD2	-6702.0	-3836.0
PSMD3	-2532.0	-3242.0
PSMD4	-5648.0	4994.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
PSMD7	-6943.0	7625.0
PSMD8	1978.0	7546.0
PSMD9	7707.5	-894.5
PSME1	2907.0	5905.0
PSME2	1270.0	-4595.0
PSME3	752.0	7366.0
PSME4	-6830.0	8511.0
PSMF1	5087.0	4771.0
PTCD3	-2827.0	6093.0
PTEN	-5726.0	8365.0
PTP4A2	3118.0	8121.0
PTRH2	-3116.0	273.0
PUM2	-6583.0	5351.0
QARS1	-2466.0	-794.0
QSOX1	7456.0	1100.0
RAB10	-5609.0	8060.0
RAB11A	-3713.0	8250.0
RAB11B	4309.0	4748.0
RAB12	-1057.0	8176.0
RAB13	3302.5	1698.5
RAB14	-4203.0	5569.0
RAB15	6826.0	4509.0
RAB17	90.0	2004.0
RAB18	-6358.0	6912.0
RAB19	5789.0	4435.0
RAB1A	-6571.0	7889.0
RAB1B	-80.0	-4574.0
RAB20	-4394.0	-3245.0
RAB21	-2903.0	7574.0
RAB22A	-5590.0	-1302.0
RAB23	6909.0	-2600.0
RAB24	4481.0	-5649.0
RAB25	7178.0	-2991.0
RAB26	1891.0	-3294.0
RAB27A	7997.0	1512.0
RAB27B	-4838.0	5533.0
RAB29	-3337.0	4447.0
RAB2A	-5653.0	7957.0
RAB2B	408.0	-35.0
RAB30	6435.0	5622.0
RAB31	3839.0	8541.0
RAB33B	2372.0	6149.0
RAB34	4880.0	-5413.0
RAB35	-1301.0	5850.0
RAB36	690.0	-5670.0
RAB37	1244.0	-5646.0
RAB38	-6913.0	3044.0
RAB39A	-2191.0	1676.0
RAB39B	-1021.0	6431.0
RAB3A	-21.0	-1948.0
RAB3B	5566.0	5918.0
RAB3C	-3904.0	2697.0
RAB3D	6472.0	4535.0
RAB40B	4958.0	-829.0
RAB40C	6115.0	-5991.0
RAB42	5558.0	-6373.0
RAB43	8116.0	1573.0
RAB4A	-4186.0	1766.0
RAB4B	6400.5	-1765.5
RAB5A	1537.0	7332.0
RAB5B	5887.0	3206.0
RAB5C	3703.0	3375.0
RAB6A	-6370.0	8664.0
RAB6B	7529.0	1278.0
RAB7A	-5898.0	8083.0
RAB7B	-5496.0	5451.0
RAB8A	-855.0	2596.0
RAB8B	3129.0	7133.0
RAB9A	-412.0	7818.0
RABGGTA	-4457.0	-3560.0
RABGGTB	-3446.0	2196.0
RAD18	7614.0	6266.0
RAD21	-2278.0	8063.0
RAD23A	-5824.0	-2416.0
RAD23B	-6778.0	7740.0
RAD52	708.0	-2726.0
RAE1	3041.0	-1934.0
RAET1G	-5737.0	-420.0
RAET1L	-5737.0	-420.0
RANBP2	-4575.0	8132.0
RANGAP1	-2328.0	-1549.0
RARA	183.0	-5463.0
RARS1	-4439.0	6407.0
RARS2	-6308.0	6760.0
RBBP5	-4912.0	-38.0
RBBP7	2154.0	6750.0
RBX1	-391.0	3201.0
RCE1	-2692.0	59.0
RCN1	6884.5	3888.5
RECK	5456.0	4804.0
RELA	2579.0	-2368.0
REN	-734.0	-1495.0
RENBP	-3824.0	-6639.0
RFT1	5663.5	-3801.5
RGS11	7231.0	-5694.0
RGS6	2513.0	1662.0
RGS7	552.0	-1242.0
RGS9	5574.0	-5107.0
RHOA	-5203.0	7671.0
RHOT1	1355.0	8586.0
RING1	2092.0	-5540.0
RIPK1	-2977.0	5088.0
RIPK2	5953.0	6306.0
RNF103	4818.0	3457.0
RNF123	3678.0	-5288.0
RNF128	-3314.0	5251.0
RNF139	-193.0	7634.0
RNF144A	-1187.0	7409.0
RNF146	560.0	7077.0
RNF152	-5942.0	-6366.0
RNF168	-4872.0	8120.0
RNF181	-3543.0	2524.0
RNF185	2705.0	5366.0
RNF2	-3811.0	8651.0
RNF20	-4475.0	4136.0
RNF40	534.0	-5046.0
RNF5	-1555.0	-4449.0
RNF7	-2546.0	5701.0
RORA	-3317.0	3869.0
RPA1	4920.0	5750.0
RPL11	5748.0	1403.0
RPL12	6107.0	-5604.0
RPL13	5686.0	-3760.0
RPL14	5110.0	-1875.0
RPL18	2523.0	-625.0
RPL18A	4545.0	-3218.0
RPL19	4654.0	6782.0
RPL21	-1686.0	8463.0
RPL22	2365.0	459.0
RPL22L1	-5123.0	-6294.0
RPL23	-205.0	4253.0
RPL24	-409.0	6813.0
RPL26	3650.0	8722.0
RPL28	6714.0	4753.0
RPL29	2613.0	4628.0
RPL3	5378.0	1155.0
RPL30	4372.0	3664.0
RPL31	6732.0	-1507.0
RPL32	2989.0	8728.0
RPL34	661.0	7140.0
RPL35	5949.0	8834.0
RPL35A	-1509.0	6565.0
RPL36	7543.0	-2424.0
RPL36A	-5983.0	4837.0
RPL36AL	1793.0	-2074.0
RPL37	2109.0	-667.0
RPL38	5601.0	5675.0
RPL3L	-5986.0	4937.0
RPL4	2582.0	8471.0
RPL6	572.0	7594.0
RPL7	-5186.0	8598.0
RPL8	3526.0	820.0
RPLP2	3550.0	3555.0
RPN1	-7121.0	7464.0
RPN2	-5521.0	3974.0
RPS13	7174.0	315.0
RPS14	4070.0	4443.0
RPS15	7253.0	6174.0
RPS16	6244.0	1119.0
RPS17	5667.0	7685.0
RPS18	4253.0	-526.0
RPS19	6565.0	-1215.0
RPS2	7322.0	4216.0
RPS21	7111.0	-6494.0
RPS25	4261.0	8455.0
RPS27A	-133.0	-1807.0
RPS28	7208.0	-396.0
RPS3	2340.0	4381.0
RPS3A	-3115.0	8824.0
RPS4X	2522.0	7391.0
RPS5	3848.0	7515.0
RPS6	-1700.0	8603.0
RPS8	3874.0	7646.0
RPS9	-1719.0	-2555.0
RRAGA	-3310.0	5815.0
RTF1	931.0	5957.0
RTN4RL1	3899.0	1236.0
RTN4RL2	2427.0	6719.0
RUVBL1	-418.0	-738.0
RWDD3	-538.0	-1052.0
RXRA	-5143.0	1552.0
SAE1	2001.0	-2412.0
SAFB	-1933.0	-1132.0
SAR1B	-3423.0	7668.0
SARS1	-2185.0	3720.0
SARS2	5893.5	-4866.5
SATB1	-1732.0	4168.0
SATB2	-6836.0	401.0
SBSPON	-4153.0	3078.0
SCFD1	-5793.0	7896.0
SCMH1	2113.0	-1086.0
SDC2	-6850.0	7623.0
SEC11A	-6674.0	2097.0
SEC11C	-5093.0	4777.0
SEC13	-1432.0	3604.0
SEC16A	-1511.0	3230.0
SEC16B	8007.0	2261.0
SEC22A	3566.0	5061.0
SEC22B	-4623.0	5601.0
SEC22C	5970.0	-5637.0
SEC23A	-3552.0	8413.0
SEC23IP	-1834.0	5924.0
SEC24A	159.0	5121.0
SEC24B	-570.0	-3344.0
SEC24C	-5965.0	-1916.0
SEC24D	-6384.0	8428.0
SEC31A	835.0	-552.0
SEC61A1	-6475.0	-2203.0
SEC61A2	-3708.0	-6590.0
SEC61B	-6411.0	-260.0
SEC61G	-2855.0	8720.0
SEH1L	2204.0	6910.0
SEL1L	-7264.0	7670.0
SELENOS	-3903.0	1995.0
SEMA5A	-5557.0	182.0
SEMA5B	3538.0	-4929.0
SENP1	5353.0	4546.0
SENP2	-4849.0	3327.0
SENP5	-5403.0	5742.0
SENP8	-2416.0	-1768.0
SERP1	-6709.0	8229.0
SERPINA1	8234.0	4905.0
SERPINA10	292.0	-3155.0
SERPINC1	-5479.0	2358.0
SERPIND1	-2147.0	-4608.0
SFTPD	2896.0	3018.0
SHC1	568.0	1962.0
SHISA5	5496.0	-442.0
SHPRH	-931.0	1674.0
SIAH1	4474.0	5949.0
SIAH2	1504.0	-2759.0
SIN3A	4581.0	6116.0
SKIV2L	3667.0	-6264.0
SKP1	-6803.0	8394.0
SKP2	5738.0	-4232.0
SLC17A5	2333.0	243.0
SLC30A5	-5633.0	5865.0
SLC30A6	-1724.0	1397.0
SLC30A7	-3589.0	5870.0
SLC30A8	3357.0	-1419.0
SLC34A1	-4925.0	-5775.0
SLC34A2	1862.0	3377.0
SLC35A1	-5778.0	918.0
SLC35C1	-399.0	-4005.0
SMAD1	5880.0	5459.0
SMAD2	2671.0	7154.0
SMAD3	-1639.0	-2520.0
SMAD4	3068.0	901.0
SMAD7	-2050.0	-4957.0
SMC1A	-2764.0	6742.0
SMC3	-4007.0	8640.0
SMC5	1029.0	5161.0
SMC6	2636.0	7994.0
SMURF2	-6772.0	5752.0
SNCA	-350.0	3820.0
SNCAIP	5168.0	4839.0
SNX3	-6131.0	6439.0
SOCS2	4529.0	3280.0
SOCS3	4231.0	7185.0
SOCS5	1959.0	-4114.0
SOCS6	-3917.0	5004.0
SORL1	6003.0	-3663.0
SP3	-2425.0	6930.0
SPARCL1	5687.0	8683.0
SPCS1	-5914.0	4706.0
SPCS2	-6962.0	7155.0
SPCS3	4330.0	1501.0
SPHK1	6446.0	-1574.0
SPON1	8083.0	8251.0
SPON2	1919.0	3082.0
SPP1	8204.0	5504.0
SPP2	4245.0	-2291.0
SPRN	-3817.0	3737.0
SPSB1	7434.0	4252.0
SPSB2	-6665.0	-4813.0
SPSB3	-6341.0	1346.0
SPSB4	-5638.0	-1459.0
SPTA1	-2878.0	4811.0
SPTAN1	7051.0	7359.0
SPTB	7834.0	-4096.0
SPTBN1	4136.0	7630.0
SPTBN2	7922.0	-2952.0
SPTBN5	4733.0	-1695.0
SRD5A3	-2854.0	4649.0
SRP14	372.0	5948.0
SRP19	-4136.0	5550.0
SRP54	-4728.0	8835.0
SRP68	-2952.0	5498.0
SRP72	-4187.0	8263.0
SRP9	-5608.0	6951.0
SRPRA	-863.0	3844.0
SRPRB	-4529.0	4441.0
SSR1	-6752.0	8281.0
SSR2	-6516.0	6915.0
SSR3	-5773.0	7803.0
SSR4	4091.0	1326.0
ST3GAL1	3065.0	8669.0
ST3GAL2	6089.0	121.0
ST3GAL3	-3090.0	3648.0
ST3GAL4	-1264.0	1193.0
ST3GAL5	2957.0	7714.0
ST3GAL6	774.0	7961.0
ST6GAL1	4830.0	6368.0
ST6GALNAC2	-6427.0	-3901.0
ST6GALNAC3	4083.0	6940.0
ST6GALNAC4	-365.0	4860.0
ST6GALNAC5	4795.0	4204.0
ST6GALNAC6	4180.5	5612.5
ST8SIA1	-6658.0	-1492.0
ST8SIA3	4668.0	-4083.0
ST8SIA4	-6249.0	6735.0
ST8SIA6	-7197.0	6205.0
STAG1	-4924.0	6068.0
STAG2	-3857.0	8559.0
STAM	-2360.0	4932.0
STAM2	494.0	2564.0
STAMBP	1626.0	5615.0
STAMBPL1	4161.0	6099.0
STAT3	8126.0	4982.0
STC2	5064.0	3301.0
STT3A	-6845.0	4709.0
STX17	4886.0	-671.0
STX1A	2774.0	-2559.0
STX5	-4974.0	-4939.0
SUDS3	2620.0	2169.0
SULT1A3	3145.5	-3951.5
SUMF1	-6426.0	292.0
SUMO1	-4690.0	8345.0
SUMO2	-2663.5	8652.5
SUMO3	-7259.0	7825.0
SUZ12	-1028.0	8662.0
SYVN1	-7005.0	-3045.0
TAB1	7839.0	-5339.0
TADA2B	2387.0	-951.0
TADA3	-1946.0	-303.0
TAF10	-3030.0	2638.0
TAF9B	-362.0	4853.0
TARS1	-5804.0	7206.0
TARS2	-5.0	-2575.0
TATDN2	1155.5	5361.5
TBC1D20	1958.0	574.0
TBCA	-3096.0	8543.0
TBCB	5388.0	4867.0
TBCC	4327.0	-6146.0
TBCD	2158.0	-2480.0
TBCE	5889.0	3825.0
TCF7L2	-4057.0	-2326.0
TCP1	-6476.0	7694.0
TDG	3401.0	6850.0
TF	6988.0	4696.0
TFAP2A	5071.0	350.0
TFAP2B	5540.0	-18.0
TFG	-5471.0	5860.0
TFPT	5935.0	1305.0
TGFA	4979.0	2380.0
TGFB1	-1851.0	6152.0
TGFBI	1470.0	6836.0
TGFBR1	-2001.0	7866.0
TGFBR2	930.0	7719.0
TGOLN2	-6334.0	4798.0
THBS1	8000.0	8780.0
THBS2	-3256.0	8633.0
THRA	-5014.0	2323.0
THRB	-6455.0	-1228.0
THSD1	7418.0	2048.0
THSD4	5121.0	4561.0
THSD7A	2585.0	6050.0
THSD7B	-3715.0	-1612.0
THY1	703.0	1982.0
TIMP1	-2454.0	3444.0
TLN1	-2076.0	-2832.0
TMED10	-6147.0	6432.0
TMED2	-2351.0	6953.0
TMED3	-6313.0	3992.0
TMED7	-4902.5	7760.5
TMED9	-5309.0	-1036.0
TMEM115	1699.0	-4432.0
TMEM129	6222.0	-765.0
TMEM132A	-1425.0	1067.0
TNC	7133.0	6992.0
TNFAIP3	-151.0	2986.0
TNIP1	5757.0	-2590.0
TNIP2	7153.0	-6672.0
TNIP3	1974.0	5640.0
TNKS	7493.0	2959.0
TNKS2	-3624.0	4091.0
TOMM20	7388.0	3171.0
TOMM70	-6096.0	7854.0
TOP1	-7160.0	8404.0
TOP2A	3804.0	1969.0
TOP2B	-411.0	8373.0
TOPORS	4771.0	6078.0
TP53	2557.0	-3561.0
TP53BP1	-6540.0	-1951.0
TPGS1	1606.0	-5265.0
TPGS2	-3867.0	4211.0
TPP1	-6909.0	4099.0
TPR	-4239.0	8611.0
TPST1	-1632.0	2591.0
TPST2	5077.0	-171.0
TRAF2	3405.0	-3806.0
TRAF3	-6416.0	5442.0
TRAF6	1082.0	6626.0
TRAM1	-7037.0	8086.0
TRAPPC1	-1429.0	4746.0
TRAPPC10	2000.0	2916.0
TRAPPC2	-3263.0	6403.0
TRAPPC2L	3633.0	-4527.0
TRAPPC3	593.0	5718.0
TRAPPC4	-1321.0	-410.0
TRAPPC5	-2311.0	-1472.0
TRAPPC6A	7806.0	-5370.0
TRAPPC6B	978.0	7705.0
TRAPPC9	1611.0	-4039.0
TRIM13	-4674.0	7419.0
TRIM25	-5042.0	-3205.0
TRIM27	-452.0	-3380.0
TRIM28	-1390.0	-6154.0
TRMT112	-6614.0	-1009.0
TRRAP	489.0	-6329.0
TSFM	-2770.0	-6449.0
TSHB	5602.0	-4369.0
TSPAN14	-6627.0	1158.0
TSPAN15	7102.0	3531.0
TSPAN33	657.0	-4997.0
TSPAN5	-6453.0	3223.0
TSPYL2	3069.0	3654.0
TSTA3	4940.0	53.0
TTF1	-4501.0	-2293.0
TTL	-747.0	7210.0
TTLL1	-3190.0	3436.0
TTLL10	3707.0	-6689.0
TTLL11	7623.0	-2769.0
TTLL12	-3831.0	-493.0
TTLL13P	5732.5	-5749.5
TTLL3	-1884.5	-6510.5
TTLL4	610.0	-658.0
TTLL7	-5404.0	6410.0
TTLL9	5284.0	-1248.0
TTR	-6090.0	3451.0
TUBA1A	-1927.0	8153.0
TUBA1B	-2891.0	7211.0
TUBA1C	-3546.0	8104.0
TUBA4A	-5187.0	7242.0
TUBA8	2488.0	-2512.0
TUBB1	-954.0	3430.0
TUBB2A	1093.0	8351.0
TUBB2B	3491.0	6524.0
TUBB4A	-797.0	-1288.0
TUBB4B	-5222.0	8679.0
TUBB6	-3844.0	-5018.0
TUFM	-2876.0	2310.0
TULP4	-6907.0	5816.0
TUSC3	-5686.0	4758.0
TXN	-5397.0	-2909.0
UAP1	-7245.0	1255.0
UBA1	-3069.0	6814.0
UBA2	2443.0	2353.0
UBA3	-3218.0	8194.0
UBA52	7488.0	-4269.0
UBA6	-6905.0	6312.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
UBD	-4391.0	-3707.0
UBE2A	-4551.0	7336.0
UBE2B	-4389.0	7152.0
UBE2C	733.0	-1864.0
UBE2D1	5638.0	3025.0
UBE2D2	-935.0	6690.0
UBE2D3	-5084.0	8317.0
UBE2E1	-6831.0	8405.0
UBE2E3	441.0	4538.0
UBE2F	-4113.5	4926.5
UBE2G1	6022.0	6179.0
UBE2G2	-6897.0	3570.0
UBE2H	-2417.0	3799.0
UBE2I	5599.0	2810.0
UBE2J2	-1329.0	4541.0
UBE2K	-3148.0	7485.0
UBE2L3	-4226.5	5465.5
UBE2L6	809.0	5322.0
UBE2M	3424.0	2257.0
UBE2Q2	-701.0	7516.0
UBE2R2	-4372.0	2763.0
UBE2S	4549.0	-1742.0
UBE2T	-5289.0	-307.0
UBE2V2	-4079.0	8295.0
UBE2W	-2829.5	4199.5
UBE2Z	1411.0	812.0
UBXN1	1787.0	5401.0
UBXN7	873.0	2038.0
UCHL1	5914.0	7628.0
UCHL3	-5410.0	8491.0
UCHL5	539.0	3983.0
UGGT1	-6296.0	6707.0
UGGT2	3828.0	-1185.0
UHRF2	-6783.0	2893.0
UIMC1	2157.0	101.0
ULBP2	-5737.0	-420.0
UMOD	-6036.0	-707.0
USO1	-6682.0	8749.0
USP10	-1816.0	-1370.0
USP11	4108.0	-5507.0
USP12	-4059.0	3490.0
USP13	-642.0	3525.0
USP14	-6057.0	7777.0
USP15	-3586.0	8355.0
USP16	-5561.0	7667.0
USP18	-5163.5	-2484.5
USP19	-5375.0	-6205.0
USP2	7977.0	982.0
USP20	-4736.0	-5752.0
USP21	-4905.0	-5030.0
USP22	7555.0	4744.0
USP24	-1240.0	1404.0
USP25	6200.0	7993.0
USP28	5188.0	3798.0
USP3	-2289.0	-1034.0
USP30	2472.0	-4526.0
USP33	-7002.0	7120.0
USP34	-5195.0	7843.0
USP37	-2860.0	6585.0
USP4	-3801.0	1470.0
USP42	5235.0	-2774.0
USP44	-3242.0	2971.0
USP47	-4602.0	8299.0
USP48	-1480.0	-3844.0
USP49	7716.0	-102.0
USP5	2291.0	1038.0
USP7	-4172.0	7828.0
USP8	-6428.0	2267.0
USP9X	-5668.0	7709.0
VAMP2	8086.5	-3275.5
VARS1	7544.0	-5251.0
VARS2	2311.0	-4975.0
VBP1	-5361.0	8016.0
VCAN	-3773.0	1454.0
VCP	-7069.0	5449.0
VCPIP1	1610.0	2928.0
VCPKMT	3998.0	-1277.0
VDAC1	6.0	6549.0
VDAC2	5362.0	3837.0
VDAC3	-6101.0	8417.0
VDR	3336.0	-653.0
VNN1	6246.0	7250.0
VWA1	-6465.0	122.0
WAC	-5426.0	8294.0
WARS1	2233.0	2888.0
WARS2	-3058.0	-2683.0
WDR20	3555.0	-4931.0
WDR48	-2737.0	3854.0
WDR5	3835.0	954.0
WDR61	2802.0	-446.0
WDTC1	-6026.0	-585.0
WFS1	7688.0	-3009.0
WIPI1	6796.0	577.0
WRAP53	-1056.0	-2787.0
WRN	1837.0	6937.0
WSB1	7892.0	1113.0
WSB2	-3548.0	3725.0
XBP1	-7174.0	6737.0
XPC	7574.0	13.0
XPNPEP2	7580.0	-3778.0
XRCC4	-4715.0	7026.0
XRN2	7433.0	6374.0
YARS1	-6414.0	4044.0
YARS2	-4678.0	-2621.0
YIF1A	3344.0	-4201.0
YKT6	2462.0	3655.0
YOD1	-4847.0	7078.0
YY1	-5129.0	3260.0
ZBTB16	2742.0	1122.0
ZBTB17	2405.0	-590.0
ZDHHC2	-5398.0	353.0
ZNF131	-3173.0	8158.0
ZRANB1	6769.0	5090.0

---

---

Immune System

Immune System

metric	value
setSize	1784
pMANOVA	4.99e-20
p.adjustMANOVA	1.4e-17
s.dist	0.146
s.diabetes	-0.0631
s.mitoG	0.132
p.diabetes	1.37e-05
p.mitoG	9.46e-20

Top 20 genes

Gene	diabetes	mitoG
IGHV1-69	-7353.5	8845.5
MNDA	-7345.0	8836.0
IGKV4-1	-7301.0	8840.0
HSP90AA1	-7286.0	8742.0
PNP	-7335.0	8459.0
HSP90B1	-7279.0	8368.0
ERP44	-7159.0	8460.0
HSPA8	-7307.0	8180.0
RAP1A	-6787.0	8805.0
PSMC6	-6851.0	8666.0
UBB	-7104.0	8341.0
CANX	-6936.0	8532.0
KPNA4	-6802.0	8691.0
EIF4G2	-6764.0	8704.0
CAPZA1	-6942.0	8474.0
DNAJC3	-7149.0	8179.0
HMOX1	-7076.0	8232.0
PSME4	-6830.0	8511.0
UBE2E1	-6831.0	8405.0
SKP1	-6803.0	8394.0

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
AAAS	5561.0	-2261.0
AAMP	69.0	-4287.0
ABCA13	7345.0	5289.0
ABCE1	-5766.0	8831.0
ABHD17A	6198.0	-5972.0
ABHD17B	-5256.0	7454.0
ABHD17C	2020.0	-2013.0
ABI1	-4630.0	8305.0
ABI2	4154.0	8369.0
ABL1	5557.0	-3567.0
ACAA1	7141.0	-6777.0
ACLY	394.0	2995.0
ACP3	4267.0	4720.0
ACTB	-4152.0	7953.0
ACTG1	-1502.0	1482.0
ACTN2	-160.0	4310.0
ACTR10	268.0	6666.0
ACTR1A	965.0	5035.0
ACTR1B	1842.0	570.0
ACTR2	-5189.0	7356.0
ACTR3	-3716.0	8206.0
ADAM10	-6444.0	8149.0
ADAM17	-5121.0	3275.0
ADAM8	-5171.0	-1538.0
ADAR	4854.0	-5902.0
ADGRE5	-2363.0	6199.0
ADGRG3	6332.0	-5786.0
AGA	2406.0	-3450.0
AGER	5844.0	-3308.0
AGL	6768.0	2825.0
AGPAT2	-4051.0	-2429.0
AHCYL1	-5585.0	5114.0
AIM2	-1476.0	-755.0
AIP	-549.0	3479.0
AKT1	4859.0	7244.0
AKT2	-4939.0	3281.0
AKT3	-375.0	7862.0
ALAD	2122.0	-5915.0
ALDH3B1	7287.0	4258.0
ALDOA	6979.5	3652.5
ALDOC	8058.0	-926.0
ALOX5	5079.0	-1468.0
ALPK1	5173.0	-5980.0
AMPD3	7453.0	2602.0
ANAPC1	-6298.0	2903.0
ANAPC10	-1783.0	4951.0
ANAPC13	-4345.0	4356.0
ANAPC2	-3336.0	-4659.0
ANAPC4	6315.0	5808.0
ANAPC5	6285.0	-1473.0
ANAPC7	5249.0	-3454.0
ANGPT1	-6415.0	8155.0
ANO6	-6150.0	7153.0
ANPEP	3600.0	1770.0
ANXA1	7055.0	8221.0
ANXA2	-337.0	8406.0
AOC1	5592.0	-5405.0
AP1B1	5867.0	-3224.0
AP1G1	-6928.0	3255.0
AP1M1	2796.0	-3928.0
AP1M2	7170.0	-121.0
AP1S1	-667.0	-1428.0
AP1S2	-2308.0	7787.0
AP1S3	483.0	-6543.0
AP2A1	3192.0	-2941.0
AP2A2	-6231.0	249.0
AP2B1	-3990.0	7426.0
AP2M1	5073.0	2926.0
AP2S1	587.0	7094.0
APAF1	-1681.0	4531.0
APBB1IP	-5251.0	-2322.0
APEH	328.0	-4272.0
APOB	7604.0	5782.0
APP	-5115.0	6758.0
APRT	7257.0	-2499.0
ARAF	4130.0	-5879.0
AREL1	-3567.0	4170.0
ARF1	-5273.0	7470.0
ARG1	203.0	-1236.0
ARHGAP9	-425.0	-2275.0
ARIH1	-4566.0	6687.0
ARIH2	7119.0	4936.0
ARL2	7475.0	-2736.0
ARL8A	1646.0	-4501.0
ARMC8	2586.0	6569.0
ARPC1A	-1009.0	-3070.0
ARPC1B	7126.0	2266.0
ARPC2	-4512.0	8767.0
ARPC3	-5747.0	8757.0
ARPC4	3077.0	1525.0
ARPC5	920.0	7514.0
ARRB1	-6250.0	3030.0
ARRB2	-3644.0	681.0
ARSA	4080.0	-2367.0
ARSB	-5231.0	2994.0
ARTN	115.0	1230.0
ASAH1	-720.0	8441.0
ASB1	5747.0	-5391.0
ASB11	8005.0	3354.0
ASB13	-4592.0	5233.0
ASB14	4009.0	1161.0
ASB15	2791.0	-2241.0
ASB16	-285.0	-261.0
ASB18	-1279.0	-1197.0
ASB2	-4035.0	3690.0
ASB3	-3110.0	1156.0
ASB4	2909.0	2350.0
ASB5	1025.0	-247.0
ASB6	2948.0	-2420.0
ASB7	4873.0	2631.0
ASB8	-2617.0	6851.0
ASB9	-6461.0	6880.0
ATF1	-4649.0	7196.0
ATF2	-4162.0	7780.0
ATG12	4089.0	7392.0
ATG5	-6142.0	8549.0
ATG7	7859.0	-906.0
ATOX1	8025.0	-3520.0
ATP11A	-7323.0	505.0
ATP11B	2684.0	5073.0
ATP6AP2	596.0	3605.0
ATP6V0A1	936.0	1549.0
ATP6V0A2	-6781.0	997.0
ATP6V0A4	7949.0	5065.0
ATP6V0B	-1247.0	-3182.0
ATP6V0C	1078.0	-2076.0
ATP6V0D1	-3890.0	3817.0
ATP6V0D2	3320.0	5793.0
ATP6V0E1	1832.0	3873.0
ATP6V0E2	158.0	-4784.0
ATP6V1A	4631.0	5077.0
ATP6V1B1	7324.0	-1200.0
ATP6V1B2	2487.0	2135.0
ATP6V1C1	-3690.0	-528.0
ATP6V1C2	3469.0	5006.0
ATP6V1D	-3259.0	8108.0
ATP6V1E1	-704.0	8548.0
ATP6V1F	5567.0	1498.0
ATP6V1G1	7327.0	4738.0
ATP6V1G2	-2452.0	921.0
ATP6V1G3	-2690.0	4036.0
ATP6V1H	-1095.0	8501.0
ATP7A	-3222.0	7692.0
ATP8A1	-2763.0	5337.0
ATP8B4	-4965.0	-4796.0
B2M	5339.0	4978.0
B4GALT1	-356.0	-3621.0
BAIAP2	7911.0	534.0
BATF	574.0	313.0
BCL10	-3598.0	5942.0
BCL2	-1449.0	-2113.0
BCL2L1	1254.0	3623.0
BCL6	-4525.0	36.0
BIN2	-3519.0	1037.0
BIRC2	-4230.0	3665.0
BIRC3	6091.0	6158.0
BIRC5	-3018.0	-2773.0
BLMH	646.0	1455.0
BLNK	6748.0	-965.0
BOLA2	5917.5	-478.5
BPIFB1	232.0	3195.0
BRAF	-6284.0	4955.0
BRAP	-3859.0	735.0
BRI3	3478.0	-3699.0
BRK1	751.0	1659.0
BRWD1	3941.0	-3907.0
BST1	5884.0	6856.0
BST2	-460.0	-4229.0
BTBD1	-5007.0	8727.0
BTBD6	2905.0	-1931.0
BTC	7701.0	1951.0
BTK	-5279.0	5486.0
BTLA	-4363.0	5386.0
BTN3A1	-3969.0	4770.0
BTNL9	-6257.0	5075.0
BTRC	3218.0	-5334.0
C1QA	-4412.0	7389.0
C1QB	-2143.0	5685.0
C1QC	-1561.0	780.0
C1R	1107.0	6557.0
C1S	644.0	7556.0
C2	-3722.0	-6399.0
C3	7675.0	3404.0
C3AR1	-1253.0	7488.0
C4A	-311.5	-5183.5
C4B	-311.5	-5183.5
C4BPA	-1940.0	-3551.0
C5AR1	-2161.0	5951.0
C5AR2	-4404.0	4162.0
C6	-1125.0	5133.0
C6orf120	-2826.0	7321.0
C7	7584.0	6501.0
C8A	-5142.0	-415.0
C8G	-3175.0	-2703.0
C9	-5622.0	-741.0
CAB39	725.0	7364.0
CALM1	-4401.0	8702.0
CALR	-7105.0	5809.0
CAMK2A	-2272.0	4664.0
CAMK2B	2551.0	5253.0
CAMK2G	5581.0	-3540.0
CAND1	-6336.0	3476.0
CANT1	6496.0	-5371.0
CANX	-6936.0	8532.0
CAP1	-1701.0	6877.0
CAPN1	7308.0	-2267.0
CAPZA1	-6942.0	8474.0
CAPZA2	-1687.0	8135.0
CAPZB	-2513.0	7203.0
CARD11	-3020.0	3028.0
CARD9	3810.0	-3371.0
CASP1	-1051.0	1558.0
CASP2	-4191.0	2262.0
CASP3	4881.0	3606.0
CASP8	-5258.0	8694.0
CASP9	2469.0	-5751.0
CAT	-602.0	4907.0
CBL	-6462.0	4306.0
CBLB	-3155.0	5963.0
CCL11	3017.0	670.0
CCL17	3224.0	2721.0
CCL19	1486.0	-2403.0
CCL2	-1079.0	3167.0
CCL22	-3491.0	4025.0
CCL4	129.5	1818.5
CCL5	-3367.0	3393.0
CCND1	7933.0	-1628.0
CCNF	4264.0	-2470.0
CCR1	-3507.0	4981.0
CCR2	-6442.0	5692.0
CCR5	-1106.0	281.0
CCR6	-1712.0	1848.0
CCT2	-5508.0	4188.0
CCT8	-6214.0	2208.0
CD101	-4774.0	2308.0
CD14	4081.0	6994.0
CD160	688.0	2601.0
CD180	-4573.0	3894.0
CD19	-2666.0	-3652.0
CD1D	5611.0	119.0
CD200	5072.0	7059.0
CD200R1	-6039.5	6134.5
CD209	-6793.0	-6525.0
CD22	-4125.0	1554.0
CD226	-3734.0	272.0
CD247	1213.0	-5666.0
CD27	1564.0	-5785.0
CD274	-1627.0	306.0
CD28	-4408.0	5134.0
CD300A	-4313.5	171.5
CD300C	-3410.0	2113.0
CD300E	3256.0	-126.0
CD300LB	-758.0	-39.0
CD300LD	-4313.5	171.5
CD300LF	-4563.0	8233.0
CD300LG	7882.0	8461.0
CD33	-6278.5	7868.5
CD34	7928.0	8147.0
CD36	-7328.0	6006.0
CD3D	-3626.0	-15.0
CD3E	-1202.0	619.0
CD3G	-1784.0	-3919.0
CD4	409.0	5008.0
CD40	-1092.0	450.0
CD44	-4381.0	6982.0
CD46	4770.0	-3118.0
CD47	-1991.0	7809.0
CD53	-3501.0	7525.0
CD55	-6863.0	6749.0
CD59	5509.5	-1796.5
CD63	-5955.0	5945.0
CD74	-4460.0	2932.0
CD79A	-4689.0	2648.0
CD79B	-2701.0	2433.0
CD80	-3453.0	3286.0
CD81	3188.0	6614.0
CD86	-2679.0	5554.0
CD8A	-3470.0	-1770.0
CD8B	-2337.5	645.5
CD93	-3514.0	7897.0
CD96	-825.0	5826.0
CDA	4457.0	-5554.0
CDC16	6701.0	3924.0
CDC20	6493.0	-3052.0
CDC23	1748.0	710.0
CDC26	-3331.0	1610.0
CDC27	-4452.0	8433.0
CDC34	-806.0	2346.0
CDC42	-5961.0	8129.0
CDH1	-1038.0	5837.0
CDK13	-1373.0	3872.0
CDKN1A	7594.0	6372.0
CEACAM1	3793.5	5357.5
CEACAM3	3793.5	5357.5
CEACAM6	3793.5	5357.5
CEACAM8	3793.5	5357.5
CEBPD	3288.0	6984.0
CENPE	1973.0	460.0
CEP290	-2988.0	5308.0
CFB	-6898.5	-6006.5
CFD	6928.0	-5898.0
CFHR1	-158.5	-105.5
CFHR2	-158.5	-105.5
CFI	5995.5	-3696.5
CFL1	-1720.0	8321.0
CFP	-3458.0	-5006.0
CGAS	323.0	-1588.0
CHI3L1	3964.0	708.0
CHRNB4	-377.0	-3200.0
CHUK	-3701.0	8556.0
CIITA	-5946.0	-2698.0
CISH	-419.0	-2121.0
CKAP4	4629.0	6520.0
CLCF1	6318.0	-5706.0
CLEC10A	-6915.0	8052.0
CLEC12A	-2696.0	5068.0
CLEC2D	-5472.0	6761.0
CLEC4A	580.0	-5426.0
CLEC4C	-6182.0	-5563.0
CLEC4E	2861.0	385.0
CLEC5A	1408.0	5146.0
CLEC6A	-4947.0	2116.0
CLEC7A	-2694.0	2149.0
CLTA	-2807.0	2774.0
CLTC	-4493.0	8248.0
CLU	7398.0	5822.0
CMTM6	-6996.0	-940.0
CNKSR1	7454.0	1081.0
CNKSR2	3628.0	-207.0
CNN2	-2669.0	6553.0
CNPY3	-4159.0	-2588.0
CNTF	3748.0	3077.0
CNTFR	7636.0	-2686.0
COL1A2	416.0	5053.0
COLEC11	631.0	3003.0
COLEC12	190.0	8600.0
COMMD3	-4289.0	8822.0
COMMD9	-1892.0	-1552.0
COPB1	-2848.0	7946.0
COTL1	8183.0	-5409.0
CPB2	7987.0	2813.0
CPN1	8159.0	-5636.0
CPN2	-1570.0	-3447.0
CPNE1	4530.0	-1637.0
CPNE3	1709.0	7633.0
CPPED1	-6207.0	6376.0
CR1	-4680.0	4418.0
CR2	-2478.0	2360.0
CRACR2A	-766.0	-6429.0
CRCP	3013.0	3745.0
CREB1	-6809.0	5166.0
CREBBP	-6181.0	3954.0
CREG1	5600.0	3619.0
CRISPLD2	4467.0	8306.0
CRK	-3124.0	6926.0
CRKL	-4195.0	3246.0
CRLF1	5990.0	141.0
CRLF2	4692.0	-3614.0
CRP	-3243.0	1012.0
CRTAM	2374.0	41.0
CSF1	-2451.0	7450.0
CSF1R	-6805.0	2322.0
CSF2RA	-2892.0	-5044.0
CSF2RB	-5554.0	-817.0
CSF3R	-5607.0	5881.0
CSK	-5802.0	-2193.0
CSNK2B	-3628.0	6622.0
CST3	2605.0	4686.0
CSTB	6639.0	3948.0
CTF1	601.0	-5358.0
CTNNB1	-6022.0	2664.0
CTSA	6070.0	1611.0
CTSB	7086.0	-1439.0
CTSC	-1974.0	7696.0
CTSD	5035.5	6716.5
CTSE	-1259.0	-4402.0
CTSF	7059.0	-4590.0
CTSH	-6661.0	6547.0
CTSK	-3257.0	7753.0
CTSO	1101.0	4475.0
CTSS	-5861.0	7572.0
CTSZ	-2861.0	2478.0
CUL1	-2997.0	6875.0
CUL2	-6236.0	8506.0
CUL3	-3105.0	8488.0
CUL5	-5371.0	8605.0
CUL7	7850.0	-5060.0
CXADR	-7100.0	3254.0
CXCL10	-3846.0	6517.0
CXCR2	-4298.0	3063.0
CYB5R3	1442.0	4432.0
CYBA	-4719.0	-4200.0
CYBB	-5520.0	5307.0
CYFIP1	3175.0	7476.0
CYFIP2	7791.0	-143.0
CYLD	-4935.0	4060.0
CYSTM1	-3557.0	5741.0
DAB2IP	7371.0	2495.0
DAPP1	-2716.0	5499.0
DBNL	3890.0	-1155.0
DCTN1	7218.0	-3098.0
DCTN2	2623.0	-2017.0
DCTN3	-715.0	689.0
DCTN4	-4133.0	7527.0
DCTN5	-4033.0	5094.0
DCTN6	4374.0	7565.0
DDOST	-5017.0	2674.0
DDX3X	3775.0	8058.0
DDX41	-6081.0	-368.0
DDX58	7214.0	-485.0
DEFB116	-6536.0	1491.0
DEFB136	996.0	2617.0
DEGS1	-4450.0	2479.0
DERA	5742.0	3035.0
DET1	-2755.5	536.5
DGAT1	5332.0	-6609.0
DHX36	-1699.0	8375.0
DHX58	-5221.0	2574.0
DHX9	-4354.0	8508.0
DIAPH1	7761.0	3677.0
DLG1	-1980.0	6587.0
DLG2	5325.0	-4513.0
DLG3	6540.0	94.0
DLG4	3487.0	-1410.0
DNAJC13	-5891.0	-1362.0
DNAJC3	-7149.0	8179.0
DNAJC5	4458.0	5657.0
DNASE1L1	5513.0	-281.0
DNM1	7171.0	3067.0
DNM2	-1598.0	5364.0
DNM3	6014.0	942.0
DOCK1	2243.0	382.0
DOCK2	-5657.0	5085.0
DOK3	-3879.0	-2058.0
DPP7	-7293.0	-6577.0
DSN1	6293.0	388.0
DSP	7655.0	6828.0
DTX3L	-5714.0	592.0
DTX4	-6400.0	5051.0
DUSP1	-2905.0	-1666.0
DUSP10	4557.0	5745.0
DUSP16	-3468.0	8092.0
DUSP2	1065.0	-4070.0
DUSP4	-2461.0	-1440.0
DUSP5	4923.0	4971.0
DUSP6	-5078.0	6412.0
DUSP7	7818.0	-3862.0
DUSP8	4090.0	3420.0
DUSP9	5294.0	-3689.0
DYNC1H1	4822.0	2594.0
DYNC1I1	3045.0	-5230.0
DYNC1I2	-251.0	7398.0
DYNC1LI1	2249.0	7292.0
DYNC1LI2	-1436.0	1861.0
DYNLL1	-6952.0	7645.0
DYNLL2	4932.0	-5028.0
DYNLT1	8238.0	-3740.0
DZIP3	-3939.0	-4126.0
EBI3	3333.0	2001.0
ECSIT	-3596.0	1408.0
EDA	4324.0	6384.0
EDA2R	8226.0	6933.0
EDAR	-769.0	-2084.0
EDARADD	6526.0	-6016.0
EEA1	-4519.0	8766.0
EEF2	-3312.0	2063.0
EGF	-4765.0	-210.0
EGFR	-6023.0	1902.0
EGR1	1105.0	4313.0
EIF2AK2	4174.0	5292.0
EIF4A1	5335.0	61.0
EIF4A2	-6848.0	-699.0
EIF4A3	2375.0	2229.0
EIF4E	-4500.0	8429.0
EIF4E2	1435.0	5962.0
EIF4E3	-232.0	4408.0
EIF4G1	-5996.0	5731.0
EIF4G2	-6764.0	8704.0
EIF4G3	-7083.0	1872.0
ELK1	3201.0	-1060.0
ELMO1	-4833.0	4917.0
ELMO2	6218.0	-536.0
ELOB	6643.0	3269.0
ELOC	-3325.0	7837.0
ENAH	5226.0	20.0
ENPP4	1750.0	7383.0
EP300	-2449.0	1336.0
ERAP1	2696.0	2291.0
ERBB2	6521.0	-6707.0
ERBB3	3712.0	-75.0
ERBB4	2718.0	2425.0
ERP44	-7159.0	8460.0
EVL	-186.0	264.0
F13A1	3019.0	4962.0
F2	-3087.0	4699.0
FABP5	3630.0	2188.0
FADD	6301.0	-5424.0
FAF2	-379.0	-899.0
FASLG	834.0	4880.0
FBXL12	6303.0	-6457.0
FBXL13	1597.0	-4376.0
FBXL14	3254.0	-5925.0
FBXL15	4607.0	-4358.0
FBXL16	4642.0	451.0
FBXL18	3324.0	-4163.0
FBXL19	-1608.0	-4038.0
FBXL20	3692.0	-5654.0
FBXL22	5538.0	-6092.0
FBXL3	-5113.0	5030.0
FBXL4	3694.0	2851.0
FBXL5	-5339.0	1379.0
FBXL7	-3047.0	1531.0
FBXL8	1855.5	-6099.5
FBXO10	-2534.0	-4069.0
FBXO11	-2703.0	8171.0
FBXO15	-1975.0	2890.0
FBXO17	3510.0	-1954.0
FBXO2	4620.0	4693.0
FBXO21	8209.0	-5962.0
FBXO22	-6695.0	4983.0
FBXO27	-2654.0	1841.0
FBXO30	-5216.0	5730.0
FBXO31	5477.0	-4217.0
FBXO32	7523.0	2250.0
FBXO4	-5534.0	5796.0
FBXO40	-4210.0	4616.0
FBXO6	7480.0	1442.0
FBXO7	-6524.0	-2660.0
FBXO9	-3297.0	-3812.0
FBXW10	-457.0	-3065.0
FBXW11	-3788.0	3125.0
FBXW12	858.0	-1111.0
FBXW2	2426.0	1249.0
FBXW4	6455.0	-3779.0
FBXW5	6633.0	-4037.0
FBXW7	-1739.0	4510.0
FBXW8	7356.0	-1698.0
FBXW9	7633.0	-5232.0
FCER1G	-3782.0	3932.0
FCER2	-3304.0	-718.0
FCGR1A	-5675.5	4265.5
FCGR1B	-5675.5	4265.5
FCGR2A	-7297.0	5966.0
FCGR2B	-7297.0	5966.0
FCGR3A	-5407.5	6212.5
FCGR3B	-5407.5	6212.5
FGA	4508.0	5893.0
FGB	3640.0	3338.0
FGF1	-6961.0	3296.0
FGF10	-2375.0	-1761.0
FGF16	3777.0	-2317.0
FGF18	5790.0	-4625.0
FGF2	792.0	3696.0
FGF22	7063.0	-4758.0
FGF9	2653.0	-2366.0
FGFR1	6753.0	-812.0
FGFR2	6750.0	6454.0
FGFR3	7673.0	-6608.0
FGFR4	-4841.0	-4690.0
FGG	5980.0	5427.0
FGL2	-5183.0	7853.0
FGR	-3144.0	378.0
FKBP1A	-2857.5	-1534.5
FLG2	7956.0	-6285.0
FLNA	-4704.0	7432.0
FLNB	7947.0	3634.0
FLT3	-3889.0	-337.0
FLT3LG	-882.0	438.0
FN1	7489.0	8379.0
FNTA	-593.0	5888.0
FNTB	3819.5	1858.5
FOLR3	4808.5	-5490.5
FOS	827.0	3751.0
FOXO1	6562.0	90.0
FOXO3	7446.0	393.0
FRK	1843.0	5921.0
FRMPD3	-5834.0	-2578.0
FRS2	-3456.0	5571.0
FRS3	-2543.0	-5274.0
FSCN1	6020.0	3898.0
FTL	-6693.0	-6771.0
FUCA1	-2319.0	5869.0
FUCA2	-6780.0	1532.0
FYN	-2200.0	6221.0
FZR1	3996.0	-5000.0
GAA	-3821.0	-2398.0
GAB1	-4598.0	-3742.0
GAB2	-717.0	7438.0
GALNS	-6518.0	51.0
GAN	7738.0	-2732.0
GATA3	7885.0	-1653.0
GBP2	-5242.0	4895.0
GBP5	-2160.0	-96.0
GBP6	-7251.0	-187.0
GCA	5307.0	2556.0
GDI2	-5894.0	8074.0
GDNF	6180.0	-48.0
GFRA1	-5626.0	-3174.0
GFRA2	-4307.0	-618.0
GFRA3	-307.0	-1564.0
GFRA4	6087.0	3762.0
GGH	6841.0	4657.0
GHDC	1575.0	-4841.0
GHR	-6922.0	4790.0
GLA	1196.0	3449.0
GLB1	-5376.0	2645.0
GLIPR1	-4306.0	6128.0
GLMN	5282.0	4715.0
GM2A	7424.0	6766.0
GMFG	3969.0	7186.0
GNS	8072.0	1691.0
GOLGA7	-2069.0	6586.0
GPI	4816.0	5422.0
GRAP2	-2907.0	5211.0
GRB2	3285.0	1922.0
GRIN1	3290.0	-5743.0
GRIN2B	-40.0	2055.0
GRIN2D	925.0	-2664.0
GRN	-4733.0	-4582.0
GSDMD	1017.0	-1040.0
GSN	7535.0	7997.0
GSTO1	8023.0	4922.0
GSTP1	1683.0	2544.0
GUSB	-7203.0	1338.0
GYG1	27.0	6415.0
GZMM	1140.0	-3497.0
H3C15	7988.0	2080.0
HACE1	1467.0	-3119.0
HAVCR2	-6021.0	6627.0
HBEGF	-6694.0	-80.0
HCK	-3484.0	-1326.0
HCST	1372.0	-4295.0
HEBP2	4787.0	3455.0
HECTD1	5015.0	3615.0
HECTD2	4950.0	-5884.0
HECTD3	6360.0	-4972.0
HECW2	-2620.0	4695.0
HERC1	7079.0	-2274.0
HERC2	-123.0	-4460.0
HERC3	7944.5	-1993.5
HERC4	-7115.0	2915.0
HERC6	-4149.0	-4400.0
HEXB	-6611.0	-740.0
HGF	-6226.0	7929.0
HGSNAT	6373.0	2744.0
HIF1A	7374.0	8562.0
HK3	-4874.0	2139.0
HLA-DMA	275.0	-5969.0
HLA-DMB	-1643.5	-3831.5
HLA-DOA	-5599.0	3997.0
HLA-DOB	-4577.0	-4767.0
HLA-DQB1	-4730.5	1217.5
HLA-DQB2	-4730.5	1217.5
HLA-DRB1	1762.5	-4711.5
HLA-DRB5	1762.5	-4711.5
HLA-E	3698.5	-6121.5
HLA-G	3698.5	-6121.5
HMGB1	2876.0	8283.0
HMOX1	-7076.0	8232.0
HMOX2	-1566.0	6596.0
HNRNPA2B1	-2132.0	-151.0
HNRNPDL	8075.0	2325.0
HNRNPF	-4812.0	5595.0
HP	-1369.5	6104.5
HPSE	50.0	-1095.0
HRAS	1503.0	-318.0
HRNR	8095.0	-6305.0
HSP90AA1	-7286.0	8742.0
HSP90AB1	-7306.0	5626.0
HSP90B1	-7279.0	8368.0
HSPA1A	-7272.5	7293.5
HSPA1B	-7272.5	7293.5
HSPA5	-7309.0	7589.0
HSPA8	-7307.0	8180.0
HSPA9	-566.0	8181.0
HUWE1	-6141.0	3624.0
HVCN1	-791.0	2937.0
ICAM1	7342.0	7752.0
ICAM2	-3483.0	7311.0
ICAM4	997.0	2998.0
ICAM5	526.0	-1886.0
ICMT	-315.0	-1207.0
ICOS	-772.0	2670.0
ICOSLG	5675.5	2737.5
IDH1	5264.0	7348.0
IFI16	-7063.5	5326.5
IFI35	236.0	-2661.0
IFIH1	-1353.0	5986.0
IFIT2	4952.0	4307.0
IFIT3	4120.0	6607.0
IFITM1	6414.0	8796.0
IFITM2	6414.0	8796.0
IFITM3	6414.0	8796.0
IFNA1	1047.0	-1753.0
IFNA10	1047.0	-1753.0
IFNA14	1047.0	-1753.0
IFNA16	1047.0	-1753.0
IFNA17	1047.0	-1753.0
IFNA2	1047.0	-1753.0
IFNA21	1047.0	-1753.0
IFNA4	1047.0	-1753.0
IFNA5	1047.0	-1753.0
IFNA6	1047.0	-1753.0
IFNA7	1047.0	-1753.0
IFNA8	1047.0	-1753.0
IFNAR1	-1479.0	4534.0
IFNAR2	-850.5	5706.5
IFNGR1	-4655.0	6148.0
IFNGR2	4633.0	5019.0
IFNLR1	5476.0	1139.0
IGF2R	7820.0	-602.0
IGHM	5659.0	-3544.0
IGHV1-69	-7353.5	8845.5
IGHV2-5	4395.0	4965.0
IGHV2-70	4395.0	4965.0
IGHV7-81	517.5	7570.5
IGKC	-2925.0	7318.0
IGKV1-12	2052.5	4944.5
IGKV1-17	2052.5	4944.5
IGKV1-39	2052.5	4944.5
IGKV1D-12	2052.5	4944.5
IGKV1D-39	2052.5	4944.5
IGKV2-30	101.5	8396.5
IGKV2D-30	101.5	8396.5
IGKV4-1	-7301.0	8840.0
IGKV5-2	-5895.0	8671.0
IGLV4-60	-3537.5	3617.5
IGLV4-69	-3537.5	3617.5
IKBKB	-1785.0	-5829.0
IKBKE	2587.0	-6365.0
IKBKG	3700.0	-677.0
IL10RA	-6326.0	3465.0
IL10RB	-4532.0	-4965.0
IL11	-3409.0	1307.0
IL11RA	-5781.5	-1048.5
IL12RB1	4540.0	-5099.0
IL12RB2	28.0	-159.0
IL13RA1	-7265.0	7820.0
IL15	-4138.0	-2350.0
IL15RA	4967.0	-4955.0
IL16	-238.0	5474.0
IL17C	-1887.0	-3210.0
IL17F	243.0	-3130.0
IL17RA	-520.0	-3946.0
IL17RB	6676.0	-3477.0
IL17RC	6671.0	-6327.0
IL17RD	2410.0	2168.0
IL17RE	6664.0	4868.0
IL18	4167.0	-3592.0
IL18BP	5260.0	-3368.0
IL18R1	1538.0	151.0
IL18RAP	-2806.0	2792.0
IL1A	-1142.0	1688.0
IL1B	-6242.0	3978.0
IL1R1	3443.0	7288.0
IL1R2	-2817.0	6793.0
IL1RAP	1964.0	5164.0
IL1RAPL1	2419.0	-1284.0
IL1RL1	-1839.0	1060.0
IL1RL2	6863.0	1080.0
IL20RB	6541.0	-1964.0
IL21R	-2522.0	-4656.0
IL22RA1	-4036.0	-1035.0
IL23A	-2852.0	2958.0
IL23R	1187.0	2344.0
IL27RA	-2587.0	1948.0
IL2RA	62.0	288.0
IL2RB	-4367.0	-223.0
IL2RG	-4350.5	-961.5
IL31RA	2141.0	-1614.0
IL33	7328.0	7911.0
IL34	-7341.0	1594.0
IL36G	-2911.0	-6370.0
IL36RN	-1984.0	3989.0
IL4	4157.0	-5043.0
IL4R	647.0	5708.0
IL5RA	-3525.0	-463.0
IL6R	-730.0	6215.0
IL6ST	-6703.0	6610.0
IL7	1813.0	-1239.0
IL7R	-5696.0	8026.0
IL9R	-50.0	-4403.0
ILF2	2872.0	3070.0
IMPDH1	1190.0	4821.0
IMPDH2	4946.0	4658.0
INPP5D	-1230.0	5535.0
INPPL1	-1829.0	-4396.0
IP6K2	6791.0	1576.0
IQGAP1	7427.0	8123.0
IQGAP2	8068.0	6890.0
IRAG2	-1956.0	-783.0
IRAK1	-3742.0	4800.0
IRAK2	-879.0	-1594.0
IRAK3	4675.0	4623.0
IRAK4	2339.0	4636.0
IRF1	3086.0	3498.0
IRF2	542.0	-3491.0
IRF3	806.0	-4184.0
IRF4	-1439.0	-700.0
IRF5	-6958.0	-2707.0
IRF6	-5647.0	2429.0
IRF7	-4522.0	2058.0
IRF8	3503.0	-706.0
IRF9	94.0	-3372.0
IRS1	7064.0	-5549.0
IRS2	-582.0	3045.0
ISG15	-1124.0	-2998.0
ISG20	-4950.0	8034.0
IST1	4515.0	-3732.0
ITCH	-4378.0	5792.0
ITGA2B	4961.0	-4170.0
ITGA4	-6762.0	7.0
ITGAL	-4315.0	-1137.0
ITGAM	3292.0	5515.0
ITGAV	8155.0	2693.0
ITGAX	-5859.0	2296.0
ITGB1	-6241.0	8758.0
ITGB2	-5238.0	412.0
ITGB3	1530.5	4298.5
ITGB5	7359.0	1316.0
ITGB7	-4595.0	346.0
ITK	-3536.0	2982.0
ITPR1	-2727.0	2512.0
ITPR2	4185.0	-2206.0
ITPR3	7844.0	5234.0
JAK1	-6481.0	8390.0
JAK2	-2268.0	5565.0
JAK3	7556.0	-6301.0
JUN	581.0	5314.0
JUNB	4544.0	2430.0
JUP	4751.0	2870.0
KBTBD13	2313.0	2189.0
KBTBD6	-6874.5	7477.5
KBTBD7	-6874.5	7477.5
KBTBD8	-2145.0	-505.0
KCMF1	-2107.0	6464.0
KCNAB2	-1327.0	724.0
KCTD6	5371.0	1842.0
KCTD7	3938.0	-338.0
KEAP1	-3703.0	-3144.0
KIF11	4262.0	-1098.0
KIF15	91.0	-5193.0
KIF18A	-2035.0	4687.0
KIF20A	3022.0	-1094.0
KIF22	-925.0	-1002.0
KIF23	6834.0	-2775.0
KIF26A	3470.0	3765.0
KIF2A	1251.0	7652.0
KIF2C	2591.0	-1946.0
KIF3A	-5126.0	3351.0
KIF3B	-3223.0	6725.0
KIF3C	-3455.0	5074.0
KIF4A	1014.0	6024.0
KIF5A	-5260.0	-5278.0
KIF5B	-1547.0	8819.0
KIF5C	6290.0	2117.0
KIFAP3	41.0	8075.0
KIT	-1277.0	3432.0
KITLG	-4636.0	7908.0
KL	-5761.0	-554.0
KLC1	143.0	-5336.0
KLC2	6949.0	-4707.0
KLC3	7232.0	-1031.0
KLC4	-6395.0	-2860.0
KLHL11	4250.0	3553.0
KLHL13	-3686.0	6045.0
KLHL2	-6669.0	8214.0
KLHL20	-3947.0	1875.0
KLHL21	7522.0	-6646.0
KLHL22	-810.5	-5052.5
KLHL25	823.0	-4743.0
KLHL3	6109.0	2377.0
KLHL41	5118.0	-6151.0
KLHL42	-111.0	-2648.0
KLHL5	4270.0	3505.0
KLHL9	-5268.0	6137.0
KLRB1	6038.0	8197.0
KLRC1	-2897.5	4049.5
KLRC2	-2897.5	4049.5
KLRD1	-3689.0	-3816.0
KLRK1	-5741.0	7328.0
KPNA1	-5632.0	8815.0
KPNA2	2229.0	5432.0
KPNA3	-1498.0	8389.0
KPNA4	-6802.0	8691.0
KPNB1	-1668.0	5829.0
KRAS	-752.0	8587.0
KSR1	-476.0	6166.0
KSR2	-7260.0	-2161.0
LAG3	-1925.0	-2900.0
LAIR1	-5670.0	-3164.0
LAMA5	8212.0	-6404.0
LAMP1	664.0	4209.0
LAMP2	-4970.0	6952.0
LAMTOR1	-81.0	-630.0
LAMTOR2	-2847.0	1280.0
LAMTOR3	2323.0	4870.0
LAT	1869.0	-481.0
LAT2	-2578.0	2305.0
LBP	4550.0	7403.0
LCK	-2194.0	5687.0
LCN2	5811.0	8293.0
LCP1	-6656.0	4745.0
LCP2	-5980.0	1266.0
LEAP2	2807.0	9.0
LGALS3	7090.0	5330.0
LGMN	7268.0	624.0
LIF	352.0	2557.0
LIFR	4755.0	4346.0
LILRA4	-7184.0	7732.0
LILRA5	-7184.0	7732.0
LILRA6	-7184.0	7732.0
LILRB3	-7184.0	7732.0
LILRB5	-7184.0	7732.0
LIMK1	3519.0	2264.0
LMNB1	6899.0	-4624.0
LMO7	6730.0	-2505.0
LNPEP	4116.0	7467.0
LNX1	7569.0	3277.0
LONRF1	6353.0	-948.0
LPCAT1	-6277.0	7035.0
LPO	5727.0	6892.0
LRG1	2288.0	4889.0
LRRC41	907.0	-3596.0
LRRC7	-883.0	-2663.0
LRRFIP1	5342.0	6570.0
LRSAM1	4703.0	-4046.0
LTA4H	-1869.0	3373.0
LTB	-2020.0	3847.0
LTBR	1443.0	561.0
LTF	-2111.0	1638.0
LTN1	-4333.0	7393.0
LY86	-3524.0	1844.0
LY96	-4879.0	364.0
LYN	-4685.0	8216.0
LYPLA1	-6790.0	7638.0
MAGT1	-6822.0	7703.0
MALT1	-2981.0	1806.0
MAN2B1	-3804.0	-5934.0
MANBA	-5693.0	-5502.0
MAOA	3741.0	-492.0
MAP2K1	7852.0	3274.0
MAP2K2	-2882.5	-4769.5
MAP2K3	3494.0	-249.0
MAP2K4	2621.0	5572.0
MAP2K6	5640.0	-4115.0
MAP2K7	3505.0	-3383.0
MAP3K1	5322.0	-960.0
MAP3K11	-195.0	-4556.0
MAP3K14	-4228.0	558.0
MAP3K3	729.0	6115.0
MAP3K7	1594.0	7480.0
MAP3K8	656.0	2671.0
MAPK1	-3928.0	6920.0
MAPK10	-2089.0	-137.0
MAPK11	4349.0	2889.0
MAPK12	3182.0	6505.0
MAPK13	8059.0	5735.0
MAPK14	-6337.0	-1012.0
MAPK3	5390.0	5167.0
MAPK7	4710.0	-703.0
MAPK8	-3252.0	1695.0
MAPK9	2849.0	6624.0
MAPKAP1	-5825.0	6111.0
MAPKAPK2	-2527.0	4587.0
MAPKAPK3	7267.0	-4297.0
MARK3	-6565.0	6767.0
MASP1	7705.0	8599.0
MASP2	-4240.0	-2143.0
MAVS	6937.0	-2375.0
MBL2	5539.0	-3910.0
MCEMP1	-5291.0	6726.0
MCL1	6260.0	-1020.0
MEF2A	-2071.0	7495.0
MEF2C	-1905.0	8451.0
MEFV	-4277.0	5186.0
MET	-7325.0	3597.0
METTL7A	1647.0	-266.0
MEX3C	-1666.0	5740.0
MGAM	561.0	417.0
MGRN1	7070.0	-883.0
MGST1	7252.0	4639.0
MIB2	2255.0	-6580.0
MICA	-449.5	-3755.5
MICB	-449.5	-3755.5
MID1	-3606.0	-3077.0
MIF	8230.0	5317.0
MKRN1	-6560.0	3886.0
MLEC	-7059.0	-620.0
MLST8	-977.0	-1211.0
MME	-2831.0	3783.0
MMP2	1375.0	7816.0
MMP25	525.0	-6432.0
MMP3	-598.0	1929.0
MMP9	-5717.0	1502.0
MNDA	-7345.0	8836.0
MOSPD2	-1998.0	8209.0
MPO	892.0	-1006.0
MRAS	6507.0	4369.0
MRC1	-5573.0	7131.0
MRC2	1541.0	7216.0
MRE11	-3060.0	3329.0
MS4A2	4446.0	3088.0
MSN	-1294.0	5246.0
MT2A	8239.0	7031.0
MTAP	-2386.0	7629.0
MTOR	-4145.0	-2344.0
MUC1	7970.0	3179.0
MUC13	3695.0	1168.0
MUC19	-1591.0	-6413.0
MUC20	3931.0	5255.0
MUC3A	4383.0	638.0
MUC4	-846.0	-343.0
MUC5B	1330.0	-4558.0
MUC6	3660.0	-6706.0
MVP	6785.0	-5147.0
MX1	-6771.0	351.0
MYC	1892.0	3123.0
MYD88	-5933.0	3612.0
MYH9	7189.0	7115.0
MYLIP	5136.0	-759.0
MYO10	4745.0	-1478.0
MYO1C	7502.0	5436.0
MYO5A	-7077.0	3216.0
MYO9B	1982.0	-237.0
NANOG	-2036.5	-2968.5
NAPRT	3730.0	-6610.0
NBEAL2	6989.0	-6392.0
NCAM1	-2962.0	3965.0
NCF1	3710.0	-659.0
NCF2	-1972.0	-3232.0
NCF4	-5987.0	5579.0
NCK1	-4610.0	8438.0
NCKAP1	-5953.0	8521.0
NCKAP1L	-1592.0	4630.0
NCKIPSD	7238.0	-4983.0
NCR1	-1842.0	-440.0
NCSTN	6534.0	860.0
NDC1	6665.0	-1084.0
NDN	894.0	5072.0
NDUFC2	4564.5	-5546.5
NECTIN2	8037.0	-2727.0
NEDD4	1235.0	7804.0
NEDD4L	1323.0	-3476.0
NEFL	7769.0	-859.0
NEU1	-4896.0	-6581.0
NF1	-3237.0	5332.0
NF2	215.0	5920.0
NFAM1	-5168.0	2355.0
NFASC	-6650.0	-793.0
NFATC1	6099.0	7170.0
NFATC2	4913.0	-5797.0
NFATC3	-5299.0	6496.0
NFKB1	5449.0	4035.0
NFKB2	2120.0	-4751.0
NFKBIA	1631.0	4830.0
NFKBIB	3850.0	467.0
NFKBIE	-4334.0	-123.0
NHLRC3	2688.0	-1139.0
NIT2	-5666.0	-1701.0
NKIRAS1	-5446.0	5927.0
NKIRAS2	7425.0	286.0
NLRC3	5548.0	-302.0
NLRC4	-6816.0	-2920.0
NLRC5	497.0	-5753.0
NLRP1	-3299.0	-5039.0
NLRP3	-5337.0	1863.0
NLRP4	2838.0	115.0
NLRX1	2674.0	-5541.0
NME2	-3826.0	-2887.0
NOD1	5283.0	4068.0
NOD2	-6286.0	2681.0
NOS1	6188.0	253.0
NOS2	-1104.0	4079.0
NOS3	1400.0	2054.0
NPC2	3922.0	3679.0
NPDC1	-4485.0	-1226.0
NPEPPS	-4943.0	-1065.0
NRAS	3837.0	7903.0
NRG1	-2730.0	4749.0
NRG2	-1154.0	1668.0
NRG4	310.0	-4609.0
NRTN	2219.0	-5311.0
NUP107	3423.0	7169.0
NUP133	2759.0	-4113.0
NUP153	-4638.0	7763.0
NUP155	6347.0	2192.0
NUP160	-5230.0	1753.0
NUP188	3880.0	-4145.0
NUP205	855.0	6303.0
NUP210	8193.0	-4172.0
NUP214	7802.0	-5326.0
NUP35	-4374.0	-921.0
NUP37	3596.0	1004.0
NUP42	4998.0	-596.0
NUP43	-2270.0	3764.0
NUP50	-4961.0	641.0
NUP54	-3355.0	6010.0
NUP58	2230.0	7116.0
NUP62	4963.0	-4765.0
NUP85	1103.0	-4750.0
NUP88	4817.0	4002.0
NUP93	5331.0	6196.0
NUP98	-2590.0	5122.0
OAS1	3456.0	-6726.0
OAS2	-6685.0	-1827.0
OAS3	-5020.0	-5338.0
OASL	-5463.0	2584.0
OLFM4	6940.0	-1244.0
OLR1	-1782.0	2913.0
OPRD1	-1261.0	-2986.0
OPRM1	-459.0	-2620.0
ORAI1	5373.0	-3312.0
ORAI2	4113.0	4514.0
ORM1	3867.5	-4259.5
ORM2	3867.5	-4259.5
ORMDL3	5642.0	-2453.0
OSBPL1A	6468.0	6678.0
OSCAR	2024.0	-1438.0
OSMR	5259.0	8374.0
OSTF1	6553.0	5854.0
OTUD5	-963.0	-1531.0
P2RX1	1145.0	5033.0
P2RX7	4651.0	4591.0
P4HB	-6743.0	5398.0
PA2G4	-2524.5	7069.5
PADI2	-2608.0	-2165.0
PAFAH1B2	-1657.0	7964.0
PAG1	-2791.0	3849.0
PAK1	-886.0	5458.0
PAK2	-4906.0	6708.0
PAK3	2878.0	1881.0
PANX1	-646.0	6554.0
PAQR3	3846.0	-6426.0
PCBP2	6135.0	1313.0
PDAP1	3245.0	700.0
PDCD1	-3283.0	5216.0
PDCD4	8018.0	3871.0
PDE12	-6351.0	7766.0
PDE3B	2729.0	6182.0
PDE6D	1227.0	4398.0
PDGFA	4317.0	4142.0
PDGFB	-990.0	-1987.0
PDGFRA	7016.0	8193.0
PDGFRB	-1814.0	8544.0
PDIA3	-7283.0	7821.0
PDPK1	-4074.0	1936.0
PDXK	8266.0	-2949.0
PDZD11	-3180.0	64.0
PEA15	-39.0	7548.0
PECAM1	3970.0	8677.0
PELI1	2295.0	5683.0
PELI2	4968.0	-157.0
PELI3	7915.0	-6062.0
PFKL	7340.0	-4515.0
PGAM1	1992.0	4530.0
PGLYRP1	-1223.0	-3101.0
PGLYRP2	-1116.0	-1352.0
PGM1	-1081.0	5048.0
PGM2	7401.0	7591.0
PGRMC1	8184.0	7942.0
PHB	312.0	5340.0
PIANP	-2775.0	-3811.0
PIAS1	3194.0	2440.0
PIGR	-1209.0	-4257.0
PIK3AP1	-6075.0	3775.0
PIK3C3	1518.0	-2612.0
PIK3CA	-6347.0	2923.0
PIK3CB	-1756.0	1880.0
PIK3CD	-1968.0	1889.0
PIK3R1	-839.0	8363.0
PIK3R2	1669.5	-3969.5
PIK3R3	3779.5	8820.5
PIK3R4	4272.0	-1214.0
PIM1	-3615.0	5315.0
PIN1	1926.0	-1497.0
PITPNA	-912.0	8721.0
PJA1	-6100.0	4703.0
PJA2	1785.0	7657.0
PKM	7561.0	7758.0
PLA2G6	-5964.0	-5304.0
PLAC8	6334.0	-3893.0
PLAU	-5613.0	-5199.0
PLAUR	4004.0	6827.0
PLCG1	8067.0	-4962.0
PLCG2	-5287.0	2474.0
PLD1	-4824.0	-1222.0
PLD2	-309.0	-2778.0
PLD3	5879.0	-2713.0
PLD4	-6072.0	4205.0
PLEKHO2	-1522.5	7084.5
PLPP5	5578.0	-5435.0
PML	6152.0	-5597.0
PNP	-7335.0	8459.0
POLR1C	1437.0	-6049.0
POLR1D	-5146.0	4592.0
POLR2E	7128.0	-3504.0
POLR2F	6184.0	-3058.0
POLR2H	4359.0	-4161.0
POLR2K	1098.0	7632.0
POLR2L	3697.0	-3808.0
POLR3A	5281.0	-1328.0
POLR3B	107.0	1125.0
POLR3C	3514.0	4844.0
POLR3D	3066.0	-666.0
POLR3E	3631.0	-4589.0
POLR3F	-2723.0	6052.0
POLR3H	200.0	3724.0
POLR3K	-5432.0	6617.0
POM121	3732.5	-6552.5
POM121C	3732.5	-6552.5
POMC	3685.0	-2222.0
POU2F1	6232.0	5561.0
PPBP	-5336.0	4394.0
PPIA	4868.0	-469.0
PPIE	6275.0	-5627.0
PPL	7566.0	183.0
PPM1B	-3071.5	4017.5
PPP1CB	-4617.0	8661.0
PPP1CC	6108.0	2839.0
PPP2CA	-5725.0	8237.0
PPP2CB	5588.0	159.0
PPP2R1A	6355.0	3115.0
PPP2R1B	-6463.0	4855.0
PPP2R5A	7319.0	1089.0
PPP2R5B	627.0	5414.0
PPP2R5C	3181.0	8384.0
PPP2R5D	2088.0	5911.0
PPP2R5E	5001.0	2898.0
PPP3CA	5123.0	6939.0
PPP3CB	-1150.0	4729.0
PPP3R1	2835.5	8199.5
PPP5C	565.0	5319.0
PRCP	-6663.0	1095.0
PRDX4	-68.0	-1128.0
PRDX6	-3287.0	3877.0
PRKACA	-530.0	15.0
PRKACB	569.0	661.0
PRKCB	-5598.0	5660.0
PRKCD	365.0	1901.0
PRKCE	-5671.0	2371.0
PRKCQ	-2002.0	-3514.0
PRKCSH	-4469.0	-2597.0
PRKDC	-5092.0	3381.0
PRKG1	-2535.0	8589.0
PRKG2	1125.0	-4521.0
PRLR	8156.0	809.0
PROS1	4907.0	7279.0
PRR5	-6098.0	-5369.0
PRSS2	-2444.0	-3110.0
PRSS3	-2444.0	-3110.0
PSAP	6220.0	-3472.0
PSEN1	-7020.0	6996.0
PSMA1	-6705.0	7838.0
PSMA2	-5464.5	6058.5
PSMA3	-3145.0	7801.0
PSMA4	-6074.0	4688.0
PSMA5	-6660.0	4497.0
PSMA6	-1954.0	8445.0
PSMA7	1612.0	7052.0
PSMA8	649.0	-4004.0
PSMB1	-5281.0	5936.0
PSMB10	3752.0	-908.0
PSMB11	1977.0	-5501.0
PSMB2	1472.0	-4144.0
PSMB3	-3388.0	5539.0
PSMB4	-4941.0	-5852.0
PSMB5	-1638.0	-2409.0
PSMB6	1806.0	-1845.0
PSMB7	-4628.0	-657.0
PSMB8	1080.0	-3793.0
PSMB9	5987.0	-4708.0
PSMC1	-1312.0	4327.0
PSMC2	-6765.0	4648.0
PSMC3	-4285.0	3386.0
PSMC4	-6423.0	7920.0
PSMC5	-4831.0	1120.0
PSMC6	-6851.0	8666.0
PSMD1	-6497.0	8619.0
PSMD10	-1613.0	2576.0
PSMD11	-6873.0	5201.0
PSMD12	-6149.0	8628.0
PSMD13	1898.0	5044.0
PSMD14	-6080.0	8262.0
PSMD2	-6702.0	-3836.0
PSMD3	-2532.0	-3242.0
PSMD4	-5648.0	4994.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
PSMD7	-6943.0	7625.0
PSMD8	1978.0	7546.0
PSMD9	7707.5	-894.5
PSME1	2907.0	5905.0
PSME2	1270.0	-4595.0
PSME3	752.0	7366.0
PSME4	-6830.0	8511.0
PSMF1	5087.0	4771.0
PSPN	-1715.0	-1537.0
PSTPIP1	-1224.0	-988.0
PTAFR	-5062.0	6031.0
PTEN	-5726.0	8365.0
PTGES2	5575.0	-1828.0
PTGS2	-2970.0	5783.0
PTK2	2264.0	6997.0
PTK2B	-5352.0	-3230.0
PTPN1	6946.0	3039.0
PTPN11	-3946.0	6142.0
PTPN12	-2782.0	8454.0
PTPN13	-3702.0	-4340.0
PTPN14	5809.0	5132.0
PTPN18	5824.0	-2434.0
PTPN2	-3709.0	8030.0
PTPN22	-5957.0	3364.0
PTPN23	3670.0	-5769.0
PTPN3	4719.0	-4814.0
PTPN4	-2725.0	7586.0
PTPN5	-1513.0	-1213.0
PTPN6	-1098.0	2140.0
PTPN7	-1757.0	-3829.0
PTPN9	2971.0	3715.0
PTPRA	-5907.0	5079.0
PTPRB	3085.0	8717.0
PTPRC	-7112.0	6863.0
PTPRJ	3203.0	5737.0
PTPRN2	5657.0	877.0
PTPRZ1	3101.0	1373.0
PTX3	-4488.0	-2545.0
PVR	-662.0	6696.0
PYCARD	6548.0	-4704.0
PYGB	5808.0	5273.0
PYGL	6729.0	1748.0
QPCT	2060.0	2678.0
QSOX1	7456.0	1100.0
RAB10	-5609.0	8060.0
RAB14	-4203.0	5569.0
RAB18	-6358.0	6912.0
RAB24	4481.0	-5649.0
RAB27A	7997.0	1512.0
RAB31	3839.0	8541.0
RAB37	1244.0	-5646.0
RAB3A	-21.0	-1948.0
RAB3D	6472.0	4535.0
RAB4B	6400.5	-1765.5
RAB5B	5887.0	3206.0
RAB5C	3703.0	3375.0
RAB6A	-6370.0	8664.0
RAB7A	-5898.0	8083.0
RAC1	-1258.0	4008.0
RAC2	-3191.0	6081.0
RACGAP1	6146.0	-2445.0
RAE1	3041.0	-1934.0
RAF1	-6377.0	2465.0
RAG2	-807.0	3988.0
RALA	-5149.0	6748.0
RALGDS	-3350.5	-786.5
RANBP2	-4575.0	8132.0
RANBP9	-2687.0	7835.0
RAP1A	-6787.0	8805.0
RAP1B	942.0	8759.0
RAP1GAP	8071.0	-849.0
RAP1GAP2	7762.0	-1501.0
RAP2B	5671.0	-1178.0
RAP2C	-4441.0	2874.0
RAPGEF1	3892.0	3396.0
RAPGEF2	-6311.0	7475.0
RAPGEF3	6998.0	-5986.0
RAPGEF4	-2613.0	5313.0
RASA1	-5274.0	8011.0
RASA2	-4929.0	8291.0
RASA3	7998.0	3778.0
RASA4	507.0	-1620.0
RASAL1	3329.0	3061.0
RASAL2	-3279.0	3861.0
RASAL3	516.0	-3980.0
RASGEF1A	777.0	-1099.0
RASGRF1	-4627.0	-3572.0
RASGRF2	5156.0	1667.0
RASGRP1	-370.0	-2734.0
RASGRP2	-326.0	-409.0
RASGRP3	-6128.0	7243.0
RASGRP4	-3063.0	1538.0
RBBP6	3444.0	5157.0
RBCK1	3790.0	-3921.0
RBSN	-6349.0	6778.0
RBX1	-391.0	3201.0
RCE1	-2692.0	59.0
RCHY1	-3461.0	4725.0
REL	-2309.0	7411.0
RELA	2579.0	-2368.0
RELB	4814.0	1355.0
RET	-3959.0	186.0
RETN	-1704.0	-1106.0
RGL1	-6436.0	-5685.0
RGL2	-4348.0	-6453.0
RGL3	7971.0	-6613.0
RHOA	-5203.0	7671.0
RHOF	5184.0	-2496.0
RHOG	2039.0	1654.0
RHOU	-961.0	5238.0
RICTOR	493.0	4810.0
RILP	4974.0	-3084.0
RIPK1	-2977.0	5088.0
RIPK2	5953.0	6306.0
RIPK3	1577.0	1519.0
RLIM	1169.0	7430.0
RNASE2	5113.5	-4405.5
RNASE3	5113.5	-4405.5
RNASE6	-2529.0	1162.0
RNASEL	7516.0	2800.0
RNASET2	8101.5	-6540.5
RNF111	-6255.0	5534.0
RNF114	-3572.0	338.0
RNF115	-528.0	6398.0
RNF123	3678.0	-5288.0
RNF125	-4936.0	7540.0
RNF126	5755.0	-4740.0
RNF130	-2655.0	5163.0
RNF138	-3827.0	7603.0
RNF14	-373.0	-1.0
RNF144B	7620.0	8253.0
RNF19A	3642.0	6667.0
RNF19B	-3119.0	-1959.0
RNF213	-6529.0	-265.0
RNF216	-840.0	5584.0
RNF217	-1791.0	3219.0
RNF220	862.0	-1325.0
RNF25	-27.0	1761.0
RNF34	48.0	4672.0
RNF4	-981.0	6419.0
RNF41	474.0	2919.0
RNF6	-6183.0	1183.0
RNF7	-2546.0	5701.0
ROCK1	-2765.0	8654.0
RORA	-3317.0	3869.0
RORC	4429.0	-1569.0
RPS27A	-133.0	-1807.0
RPS6KA1	7703.0	4452.0
RPS6KA2	7237.0	-2956.0
RPS6KA3	-6111.0	8270.0
RPS6KA5	2516.0	-3206.0
RSAD2	-4497.0	4570.0
S100A1	1975.0	8367.0
S100A11	4838.0	7913.0
S100A8	-3981.0	6893.0
S100B	1781.0	-995.0
S1PR1	4311.0	7637.0
SAMHD1	1852.0	601.0
SAR1B	-3423.0	7668.0
SARM1	2160.0	336.0
SCAMP1	7264.0	2855.0
SDC1	6076.0	6227.0
SDCBP	5668.0	4540.0
SEC13	-1432.0	3604.0
SEC22B	-4623.0	5601.0
SEC23A	-3552.0	8413.0
SEC24A	159.0	5121.0
SEC24B	-570.0	-3344.0
SEC24C	-5965.0	-1916.0
SEC24D	-6384.0	8428.0
SEC31A	835.0	-552.0
SEC61A1	-6475.0	-2203.0
SEC61A2	-3708.0	-6590.0
SEC61B	-6411.0	-260.0
SEC61G	-2855.0	8720.0
SEH1L	2204.0	6910.0
SELL	-4022.0	902.0
SERPINA1	8234.0	4905.0
SERPINA3	2345.0	8095.0
SERPINB1	7293.0	4143.0
SERPINB10	4371.0	-319.0
SERPINB6	7950.0	8360.0
SERPING1	3751.0	8403.0
SH2B1	5228.0	-6017.0
SH2D1B	-4335.0	-295.0
SH3GL2	-6503.0	867.0
SH3KBP1	3805.0	5866.0
SH3RF1	431.0	-2692.0
SHC1	568.0	1962.0
SHC3	-3555.0	-3601.0
SHOC2	-5120.0	8378.0
SIAH1	4474.0	5949.0
SIAH2	1504.0	-2759.0
SIGIRR	-826.0	-4627.0
SIGLEC1	1121.0	-6191.0
SIGLEC10	-4900.5	1627.5
SIGLEC11	-4900.5	1627.5
SIGLEC12	-2039.5	-2039.5
SIGLEC6	-6278.5	7868.5
SIGLEC7	-2039.5	-2039.5
SIGLEC8	-2039.5	-2039.5
SIGLEC9	-2039.5	-2039.5
SIKE1	2817.0	3211.0
SIPA1	-3901.0	3867.0
SIRPA	-6193.5	-6693.5
SIRPB1	-6193.5	-6693.5
SKP1	-6803.0	8394.0
SKP2	5738.0	-4232.0
SLAMF6	-693.0	-2721.0
SLAMF7	-4972.0	4007.0
SLC11A1	-1742.0	815.0
SLC15A4	-6120.0	-5883.0
SLC27A2	-6940.0	532.0
SLC2A5	8118.0	4882.0
SLC44A2	7940.0	4899.0
SLCO4C1	1461.0	-992.0
SLPI	307.0	3136.0
SMAD3	-1639.0	-2520.0
SMARCA4	-2170.0	4097.0
SMURF1	7065.0	-1671.0
SMURF2	-6772.0	5752.0
SNAP23	-6477.0	8059.0
SNAP29	-7150.0	7785.0
SNRPA1	4691.0	-2581.0
SOCS1	-253.0	-5520.0
SOCS2	4529.0	3280.0
SOCS3	4231.0	7185.0
SOCS5	1959.0	-4114.0
SOD1	-7054.0	2583.0
SOD2	-1635.0	4013.0
SOS1	-6566.0	7698.0
SOS2	-4341.0	7073.0
SPRED1	-6354.0	8554.0
SPRED2	-1328.0	-5582.0
SPRED3	3740.0	3539.0
SPSB1	7434.0	4252.0
SPSB2	-6665.0	-4813.0
SPSB4	-5638.0	-1459.0
SPTA1	-2878.0	4811.0
SPTAN1	7051.0	7359.0
SPTB	7834.0	-4096.0
SPTBN1	4136.0	7630.0
SPTBN2	7922.0	-2952.0
SPTBN5	4733.0	-1695.0
SQSTM1	-5419.0	2021.0
SRC	-2657.0	-1643.0
SRP14	372.0	5948.0
STAT1	-3464.0	-4440.0
STAT2	4437.0	-4922.0
STAT3	8126.0	4982.0
STAT4	-3850.0	4337.0
STAT5A	2714.0	-3795.0
STAT5B	4664.0	-4634.0
STAT6	-6946.0	2330.0
STBD1	-6692.0	3728.0
STIM1	7832.0	6223.0
STING1	-266.0	6780.0
STK10	-1779.0	2392.0
STK11IP	7069.0	-5659.0
STOM	2062.0	8033.0
STUB1	4177.0	-2823.0
STX1A	2774.0	-2559.0
STX3	7132.0	3726.0
STX4	-3184.0	-4491.0
STXBP2	6798.0	725.0
SUGT1	3448.0	6681.0
SUMO1	-4690.0	8345.0
SURF4	-5939.0	2804.0
SVIP	-1801.0	4362.0
SYK	-6921.0	4480.0
SYNGAP1	3589.0	-4277.0
SYNGR1	6225.0	-2427.0
TAB1	7839.0	-5339.0
TAB2	-7040.0	7307.0
TAB3	3966.0	5424.0
TALDO1	-5386.0	449.0
TANK	-4899.0	6416.0
TAP1	5427.0	-6060.0
TAP2	5211.5	-5555.5
TAPBP	6125.0	-2067.0
TARM1	6276.0	2422.0
TAX1BP1	3157.0	7948.0
TBC1D10C	4785.0	-3612.0
TBK1	-5003.0	4897.0
TCIRG1	-5363.0	-3931.0
TCP1	-6476.0	7694.0
TEC	-5516.0	6783.0
TEK	-2265.0	8575.0
TGFA	4979.0	2380.0
TGFB1	-1851.0	6152.0
THEM4	-3393.0	6155.0
THOP1	5354.0	-4286.0
TICAM1	-1539.0	-3874.0
TIFA	2278.0	5664.0
TIMP1	-2454.0	3444.0
TIMP2	4104.0	8646.0
TIRAP	-3143.0	6369.0
TKFC	5898.0	1211.0
TLN1	-2076.0	-2832.0
TLR1	-3224.0	560.0
TLR2	5407.0	5188.0
TLR3	1181.0	6018.0
TLR4	-4128.0	8470.0
TLR6	-4778.0	7142.0
TLR7	-3743.0	5769.0
TLR8	281.0	6768.0
TLR9	-3935.5	846.5
TMBIM1	5555.0	2568.0
TMC6	-5597.0	-5013.0
TMEM179B	-3249.0	-2550.0
TMEM30A	-6557.0	6632.0
TMEM63A	7912.0	1.0
TNF	-2778.0	4883.0
TNFAIP3	-151.0	2986.0
TNFAIP6	-3592.0	4376.0
TNFRSF11A	-6810.0	1873.0
TNFRSF11B	-1888.0	3637.0
TNFRSF12A	-4122.0	5462.0
TNFRSF13B	-3048.0	2198.0
TNFRSF13C	-2808.0	296.0
TNFRSF14	872.0	-1648.0
TNFRSF18	3888.0	-4305.0
TNFRSF1A	6733.0	6743.0
TNFRSF1B	-5427.0	939.0
TNFRSF25	6077.0	-6289.0
TNFRSF4	659.0	-624.0
TNFRSF9	4643.0	-1238.0
TNFSF12	6437.0	-3169.0
TNFSF13	2168.0	1972.0
TNFSF13B	5298.0	3905.0
TNFSF14	-1855.0	436.0
TNFSF15	-5351.0	-1629.0
TNFSF8	1617.0	2588.0
TNFSF9	154.0	2460.0
TNIP2	7153.0	-6672.0
TOLLIP	5721.0	3964.0
TOM1	-2514.0	-174.0
TP53	2557.0	-3561.0
TPP2	-4861.0	7558.0
TPR	-4239.0	8611.0
TRAF2	3405.0	-3806.0
TRAF3	-6416.0	5442.0
TRAF6	1082.0	6626.0
TRAF7	1593.0	1363.0
TRAIP	3739.0	2143.0
TRAPPC1	-1429.0	4746.0
TRAT1	-2279.0	-5760.0
TRBC1	-2602.5	6825.5
TREM1	169.0	-2242.0
TREM2	-4021.0	2867.0
TREML2	-3185.0	3037.0
TREML4	1759.0	-1379.0
TREX1	1252.0	2779.0
TRIB3	3661.0	-614.0
TRIM10	-3642.0	4159.0
TRIM11	5691.0	-6686.0
TRIM14	-363.0	-4547.0
TRIM17	-1955.0	-5357.0
TRIM2	-1014.5	6967.5
TRIM21	344.0	-452.0
TRIM22	773.0	258.0
TRIM25	-5042.0	-3205.0
TRIM26	1446.0	5190.0
TRIM3	7179.0	-6505.0
TRIM32	-6017.0	-3715.0
TRIM34	-1848.5	-348.5
TRIM35	-6390.0	-3932.0
TRIM36	5392.0	1747.0
TRIM37	-6310.0	-2309.0
TRIM39	-3968.0	-5404.0
TRIM41	7182.0	-6307.0
TRIM45	4625.0	-1893.0
TRIM46	6828.0	-2982.0
TRIM5	-7035.5	6679.5
TRIM56	-728.0	-4103.0
TRIM6	466.0	3154.0
TRIM62	6914.0	-31.0
TRIM63	-2296.0	2181.0
TRIM68	2033.0	1605.0
TRIM71	2231.0	-2446.0
TRIM8	-6708.0	-1824.0
TRIM9	210.0	2035.0
TRIP12	-6590.0	8167.0
TRPC1	-5396.0	1920.0
TRPM2	-2904.0	-6037.0
TSPAN14	-6627.0	1158.0
TTR	-6090.0	3451.0
TUBB	335.0	8036.0
TUBB4B	-5222.0	8679.0
TWIST1	2436.0	2787.0
TXK	861.0	-4279.0
TXLNA	1173.0	-4792.0
TXN	-5397.0	-2909.0
TXNDC5	1391.0	-669.0
TXNIP	2986.0	4021.0
TYK2	3318.0	-6265.0
TYROBP	-4245.0	2276.0
UBA1	-3069.0	6814.0
UBA3	-3218.0	8194.0
UBA5	-6506.0	1620.0
UBA52	7488.0	-4269.0
UBA6	-6905.0	6312.0
UBA7	-3088.0	-3909.0
UBAC1	6069.0	-2026.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
UBE2A	-4551.0	7336.0
UBE2B	-4389.0	7152.0
UBE2C	733.0	-1864.0
UBE2D1	5638.0	3025.0
UBE2D2	-935.0	6690.0
UBE2D3	-5084.0	8317.0
UBE2E1	-6831.0	8405.0
UBE2E2	2753.0	4580.0
UBE2E3	441.0	4538.0
UBE2F	-4113.5	4926.5
UBE2G1	6022.0	6179.0
UBE2G2	-6897.0	3570.0
UBE2H	-2417.0	3799.0
UBE2J1	-4894.0	8195.0
UBE2J2	-1329.0	4541.0
UBE2K	-3148.0	7485.0
UBE2L3	-4226.5	5465.5
UBE2L6	809.0	5322.0
UBE2M	3424.0	2257.0
UBE2O	5265.0	-1823.0
UBE2Q1	4503.0	-393.0
UBE2Q2	-701.0	7516.0
UBE2R2	-4372.0	2763.0
UBE2S	4549.0	-1742.0
UBE2U	1482.0	8032.0
UBE2V2	-4079.0	8295.0
UBE2W	-2829.5	4199.5
UBE2Z	1411.0	812.0
UBE3A	-1965.0	8537.0
UBE3B	7311.0	-3273.0
UBE3C	-674.0	2056.0
UBE3D	1867.0	-59.0
UBE4A	-6479.0	2398.0
UBOX5	2216.0	-72.0
UBR1	5243.0	6623.0
UBR2	-6912.0	-5650.0
UBR4	4082.0	-4874.0
UFL1	-1900.0	7520.0
ULBP1	-5737.0	-420.0
ULBP3	-5737.0	-420.0
UNC13D	12.0	-5070.0
UNC93B1	-2571.0	-565.0
UNKL	-7141.0	2538.0
USP18	-5163.5	-2484.5
USP41	-5163.5	-2484.5
VAMP2	8086.5	-3275.5
VAMP3	1693.0	5955.0
VAMP8	-3005.0	5301.0
VAPA	-4422.0	7382.0
VASP	-2568.0	4503.0
VAT1	7581.0	-4263.0
VAV1	-4395.0	5076.0
VAV2	2432.0	-843.0
VAV3	6942.0	5027.0
VCAM1	-4983.0	4280.0
VCL	-4796.0	7947.0
VCP	-7069.0	5449.0
VEGFA	-4619.0	-5156.0
VIM	5500.0	7940.0
VNN1	6246.0	7250.0
VPS35L	968.0	-5964.0
VRK3	-4442.0	-4059.0
VWF	7704.0	-1950.0
WAS	-11.0	299.0
WASF1	-5233.0	-3651.0
WASF2	4804.0	1618.0
WASF3	4712.0	680.0
WASL	-3989.0	7855.0
WDR83	623.0	-5865.0
WIPF1	-3718.0	7829.0
WIPF2	4034.0	-1247.0
WIPF3	7332.0	3435.0
WSB1	7892.0	1113.0
WWP1	-6879.0	6537.0
XAF1	-6155.0	1910.0
XDH	8158.0	1436.0
XRCC5	-2388.0	162.0
XRCC6	-1971.0	4034.0
YES1	-120.0	7265.0
YPEL5	8001.0	3939.0
YWHAB	-4723.0	8579.0
YWHAZ	-5614.0	8512.0
ZAP70	4159.0	1153.0
ZBP1	-6151.0	4520.0
ZBTB16	2742.0	1122.0
ZDHHC9	-2745.0	-1163.0
ZEB1	1347.0	8478.0
ZNRF1	625.0	-4092.0
ZNRF2	-7152.0	5062.0

---

---

Innate Immune System

Innate Immune System

metric	value
setSize	893
pMANOVA	2.85e-18
p.adjustMANOVA	6.66e-16
s.dist	0.189
s.diabetes	-0.0699
s.mitoG	0.175
p.diabetes	0.000443
p.mitoG	1.05e-18

Top 20 genes

Gene	diabetes	mitoG
IGHV1-69	-7353.5	8845.5
MNDA	-7345.0	8836.0
IGKV4-1	-7301.0	8840.0
HSP90AA1	-7286.0	8742.0
PNP	-7335.0	8459.0
HSP90B1	-7279.0	8368.0
ERP44	-7159.0	8460.0
HSPA8	-7307.0	8180.0
RAP1A	-6787.0	8805.0
PSMC6	-6851.0	8666.0
UBB	-7104.0	8341.0
CAPZA1	-6942.0	8474.0
DNAJC3	-7149.0	8179.0
PSME4	-6830.0	8511.0
SKP1	-6803.0	8394.0
PSMD1	-6497.0	8619.0
CLEC10A	-6915.0	8052.0
SNAP29	-7150.0	7785.0
LILRB3	-7184.0	7732.0
RAB6A	-6370.0	8664.0

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
AAMP	69.0	-4287.0
ABCA13	7345.0	5289.0
ABI1	-4630.0	8305.0
ABI2	4154.0	8369.0
ABL1	5557.0	-3567.0
ACAA1	7141.0	-6777.0
ACLY	394.0	2995.0
ACP3	4267.0	4720.0
ACTB	-4152.0	7953.0
ACTG1	-1502.0	1482.0
ACTR10	268.0	6666.0
ACTR1B	1842.0	570.0
ACTR2	-5189.0	7356.0
ACTR3	-3716.0	8206.0
ADAM10	-6444.0	8149.0
ADAM8	-5171.0	-1538.0
ADGRE5	-2363.0	6199.0
ADGRG3	6332.0	-5786.0
AGA	2406.0	-3450.0
AGER	5844.0	-3308.0
AGL	6768.0	2825.0
AGPAT2	-4051.0	-2429.0
AHCYL1	-5585.0	5114.0
AIM2	-1476.0	-755.0
ALAD	2122.0	-5915.0
ALDH3B1	7287.0	4258.0
ALDOA	6979.5	3652.5
ALDOC	8058.0	-926.0
ALOX5	5079.0	-1468.0
ALPK1	5173.0	-5980.0
AMPD3	7453.0	2602.0
ANO6	-6150.0	7153.0
ANPEP	3600.0	1770.0
ANXA2	-337.0	8406.0
AOC1	5592.0	-5405.0
AP1M1	2796.0	-3928.0
AP2A2	-6231.0	249.0
APAF1	-1681.0	4531.0
APEH	328.0	-4272.0
APOB	7604.0	5782.0
APP	-5115.0	6758.0
APRT	7257.0	-2499.0
ARG1	203.0	-1236.0
ARHGAP9	-425.0	-2275.0
ARL8A	1646.0	-4501.0
ARMC8	2586.0	6569.0
ARPC1A	-1009.0	-3070.0
ARPC1B	7126.0	2266.0
ARPC2	-4512.0	8767.0
ARPC3	-5747.0	8757.0
ARPC4	3077.0	1525.0
ARPC5	920.0	7514.0
ARSA	4080.0	-2367.0
ARSB	-5231.0	2994.0
ASAH1	-720.0	8441.0
ATF1	-4649.0	7196.0
ATF2	-4162.0	7780.0
ATG12	4089.0	7392.0
ATG5	-6142.0	8549.0
ATG7	7859.0	-906.0
ATOX1	8025.0	-3520.0
ATP11A	-7323.0	505.0
ATP11B	2684.0	5073.0
ATP6AP2	596.0	3605.0
ATP6V0A1	936.0	1549.0
ATP6V0A2	-6781.0	997.0
ATP6V0A4	7949.0	5065.0
ATP6V0B	-1247.0	-3182.0
ATP6V0C	1078.0	-2076.0
ATP6V0D1	-3890.0	3817.0
ATP6V0D2	3320.0	5793.0
ATP6V0E1	1832.0	3873.0
ATP6V0E2	158.0	-4784.0
ATP6V1A	4631.0	5077.0
ATP6V1B1	7324.0	-1200.0
ATP6V1B2	2487.0	2135.0
ATP6V1C1	-3690.0	-528.0
ATP6V1C2	3469.0	5006.0
ATP6V1D	-3259.0	8108.0
ATP6V1E1	-704.0	8548.0
ATP6V1F	5567.0	1498.0
ATP6V1G1	7327.0	4738.0
ATP6V1G2	-2452.0	921.0
ATP6V1G3	-2690.0	4036.0
ATP6V1H	-1095.0	8501.0
ATP7A	-3222.0	7692.0
ATP8A1	-2763.0	5337.0
ATP8B4	-4965.0	-4796.0
B2M	5339.0	4978.0
B4GALT1	-356.0	-3621.0
BAIAP2	7911.0	534.0
BCL10	-3598.0	5942.0
BCL2	-1449.0	-2113.0
BCL2L1	1254.0	3623.0
BIN2	-3519.0	1037.0
BIRC2	-4230.0	3665.0
BIRC3	6091.0	6158.0
BPIFB1	232.0	3195.0
BRI3	3478.0	-3699.0
BRK1	751.0	1659.0
BST1	5884.0	6856.0
BST2	-460.0	-4229.0
BTK	-5279.0	5486.0
BTRC	3218.0	-5334.0
C1QA	-4412.0	7389.0
C1QB	-2143.0	5685.0
C1QC	-1561.0	780.0
C1R	1107.0	6557.0
C1S	644.0	7556.0
C2	-3722.0	-6399.0
C3	7675.0	3404.0
C3AR1	-1253.0	7488.0
C4A	-311.5	-5183.5
C4B	-311.5	-5183.5
C4BPA	-1940.0	-3551.0
C5AR1	-2161.0	5951.0
C5AR2	-4404.0	4162.0
C6	-1125.0	5133.0
C6orf120	-2826.0	7321.0
C7	7584.0	6501.0
C8A	-5142.0	-415.0
C8G	-3175.0	-2703.0
C9	-5622.0	-741.0
CAB39	725.0	7364.0
CALM1	-4401.0	8702.0
CAND1	-6336.0	3476.0
CANT1	6496.0	-5371.0
CAP1	-1701.0	6877.0
CAPN1	7308.0	-2267.0
CAPZA1	-6942.0	8474.0
CAPZA2	-1687.0	8135.0
CARD11	-3020.0	3028.0
CARD9	3810.0	-3371.0
CASP1	-1051.0	1558.0
CASP2	-4191.0	2262.0
CASP8	-5258.0	8694.0
CASP9	2469.0	-5751.0
CAT	-602.0	4907.0
CCL17	3224.0	2721.0
CCL22	-3491.0	4025.0
CCR2	-6442.0	5692.0
CCR6	-1712.0	1848.0
CCT2	-5508.0	4188.0
CCT8	-6214.0	2208.0
CD14	4081.0	6994.0
CD180	-4573.0	3894.0
CD19	-2666.0	-3652.0
CD209	-6793.0	-6525.0
CD247	1213.0	-5666.0
CD300A	-4313.5	171.5
CD300E	3256.0	-126.0
CD300LB	-758.0	-39.0
CD33	-6278.5	7868.5
CD36	-7328.0	6006.0
CD3G	-1784.0	-3919.0
CD4	409.0	5008.0
CD44	-4381.0	6982.0
CD46	4770.0	-3118.0
CD47	-1991.0	7809.0
CD53	-3501.0	7525.0
CD55	-6863.0	6749.0
CD59	5509.5	-1796.5
CD63	-5955.0	5945.0
CD81	3188.0	6614.0
CD93	-3514.0	7897.0
CDA	4457.0	-5554.0
CDC34	-806.0	2346.0
CDC42	-5961.0	8129.0
CDK13	-1373.0	3872.0
CEACAM1	3793.5	5357.5
CEACAM3	3793.5	5357.5
CEACAM6	3793.5	5357.5
CEACAM8	3793.5	5357.5
CEP290	-2988.0	5308.0
CFB	-6898.5	-6006.5
CFD	6928.0	-5898.0
CFHR1	-158.5	-105.5
CFHR2	-158.5	-105.5
CFI	5995.5	-3696.5
CFL1	-1720.0	8321.0
CFP	-3458.0	-5006.0
CGAS	323.0	-1588.0
CHI3L1	3964.0	708.0
CHRNB4	-377.0	-3200.0
CHUK	-3701.0	8556.0
CKAP4	4629.0	6520.0
CLEC10A	-6915.0	8052.0
CLEC12A	-2696.0	5068.0
CLEC4A	580.0	-5426.0
CLEC4C	-6182.0	-5563.0
CLEC4E	2861.0	385.0
CLEC5A	1408.0	5146.0
CLEC6A	-4947.0	2116.0
CLEC7A	-2694.0	2149.0
CLU	7398.0	5822.0
CMTM6	-6996.0	-940.0
CNN2	-2669.0	6553.0
CNPY3	-4159.0	-2588.0
COLEC11	631.0	3003.0
COMMD3	-4289.0	8822.0
COMMD9	-1892.0	-1552.0
COPB1	-2848.0	7946.0
COTL1	8183.0	-5409.0
CPB2	7987.0	2813.0
CPN1	8159.0	-5636.0
CPN2	-1570.0	-3447.0
CPNE1	4530.0	-1637.0
CPNE3	1709.0	7633.0
CPPED1	-6207.0	6376.0
CR1	-4680.0	4418.0
CR2	-2478.0	2360.0
CRACR2A	-766.0	-6429.0
CRCP	3013.0	3745.0
CREB1	-6809.0	5166.0
CREBBP	-6181.0	3954.0
CREG1	5600.0	3619.0
CRISPLD2	4467.0	8306.0
CRK	-3124.0	6926.0
CRP	-3243.0	1012.0
CSNK2B	-3628.0	6622.0
CST3	2605.0	4686.0
CSTB	6639.0	3948.0
CTNNB1	-6022.0	2664.0
CTSA	6070.0	1611.0
CTSB	7086.0	-1439.0
CTSC	-1974.0	7696.0
CTSD	5035.5	6716.5
CTSH	-6661.0	6547.0
CTSK	-3257.0	7753.0
CTSS	-5861.0	7572.0
CTSZ	-2861.0	2478.0
CUL1	-2997.0	6875.0
CXCR2	-4298.0	3063.0
CYB5R3	1442.0	4432.0
CYBA	-4719.0	-4200.0
CYBB	-5520.0	5307.0
CYFIP1	3175.0	7476.0
CYFIP2	7791.0	-143.0
CYLD	-4935.0	4060.0
CYSTM1	-3557.0	5741.0
DBNL	3890.0	-1155.0
DDOST	-5017.0	2674.0
DDX3X	3775.0	8058.0
DDX41	-6081.0	-368.0
DDX58	7214.0	-485.0
DEFB116	-6536.0	1491.0
DEFB136	996.0	2617.0
DEGS1	-4450.0	2479.0
DERA	5742.0	3035.0
DGAT1	5332.0	-6609.0
DHX36	-1699.0	8375.0
DHX58	-5221.0	2574.0
DHX9	-4354.0	8508.0
DIAPH1	7761.0	3677.0
DNAJC13	-5891.0	-1362.0
DNAJC3	-7149.0	8179.0
DNAJC5	4458.0	5657.0
DNASE1L1	5513.0	-281.0
DNM1	7171.0	3067.0
DNM2	-1598.0	5364.0
DNM3	6014.0	942.0
DOCK1	2243.0	382.0
DOCK2	-5657.0	5085.0
DOK3	-3879.0	-2058.0
DPP7	-7293.0	-6577.0
DSN1	6293.0	388.0
DSP	7655.0	6828.0
DTX4	-6400.0	5051.0
DUSP4	-2461.0	-1440.0
DUSP6	-5078.0	6412.0
DUSP7	7818.0	-3862.0
DYNC1H1	4822.0	2594.0
DYNC1LI1	2249.0	7292.0
DYNLL1	-6952.0	7645.0
DYNLT1	8238.0	-3740.0
ECSIT	-3596.0	1408.0
EEA1	-4519.0	8766.0
EEF2	-3312.0	2063.0
ELK1	3201.0	-1060.0
ELMO1	-4833.0	4917.0
ELMO2	6218.0	-536.0
ENPP4	1750.0	7383.0
EP300	-2449.0	1336.0
ERP44	-7159.0	8460.0
F2	-3087.0	4699.0
FABP5	3630.0	2188.0
FADD	6301.0	-5424.0
FAF2	-379.0	-899.0
FBXW11	-3788.0	3125.0
FCER1G	-3782.0	3932.0
FCGR1A	-5675.5	4265.5
FCGR2A	-7297.0	5966.0
FCGR3A	-5407.5	6212.5
FCGR3B	-5407.5	6212.5
FGA	4508.0	5893.0
FGB	3640.0	3338.0
FGG	5980.0	5427.0
FGL2	-5183.0	7853.0
FGR	-3144.0	378.0
FLG2	7956.0	-6285.0
FOLR3	4808.5	-5490.5
FOS	827.0	3751.0
FRK	1843.0	5921.0
FRMPD3	-5834.0	-2578.0
FTL	-6693.0	-6771.0
FUCA1	-2319.0	5869.0
FUCA2	-6780.0	1532.0
FYN	-2200.0	6221.0
GAA	-3821.0	-2398.0
GAB2	-717.0	7438.0
GALNS	-6518.0	51.0
GCA	5307.0	2556.0
GDI2	-5894.0	8074.0
GGH	6841.0	4657.0
GHDC	1575.0	-4841.0
GLA	1196.0	3449.0
GLB1	-5376.0	2645.0
GLIPR1	-4306.0	6128.0
GM2A	7424.0	6766.0
GMFG	3969.0	7186.0
GNS	8072.0	1691.0
GOLGA7	-2069.0	6586.0
GPI	4816.0	5422.0
GRAP2	-2907.0	5211.0
GRB2	3285.0	1922.0
GRN	-4733.0	-4582.0
GSDMD	1017.0	-1040.0
GSN	7535.0	7997.0
GSTP1	1683.0	2544.0
GUSB	-7203.0	1338.0
GYG1	27.0	6415.0
GZMM	1140.0	-3497.0
HCK	-3484.0	-1326.0
HEBP2	4787.0	3455.0
HEXB	-6611.0	-740.0
HGSNAT	6373.0	2744.0
HK3	-4874.0	2139.0
HLA-E	3698.5	-6121.5
HMGB1	2876.0	8283.0
HMOX2	-1566.0	6596.0
HP	-1369.5	6104.5
HPSE	50.0	-1095.0
HRAS	1503.0	-318.0
HRNR	8095.0	-6305.0
HSP90AA1	-7286.0	8742.0
HSP90AB1	-7306.0	5626.0
HSP90B1	-7279.0	8368.0
HSPA1A	-7272.5	7293.5
HSPA1B	-7272.5	7293.5
HSPA8	-7307.0	8180.0
HUWE1	-6141.0	3624.0
HVCN1	-791.0	2937.0
ICAM2	-3483.0	7311.0
IDH1	5264.0	7348.0
IFI16	-7063.5	5326.5
IFIH1	-1353.0	5986.0
IFNA1	1047.0	-1753.0
IFNA10	1047.0	-1753.0
IFNA14	1047.0	-1753.0
IFNA16	1047.0	-1753.0
IFNA17	1047.0	-1753.0
IFNA2	1047.0	-1753.0
IFNA21	1047.0	-1753.0
IFNA4	1047.0	-1753.0
IFNA5	1047.0	-1753.0
IFNA6	1047.0	-1753.0
IFNA7	1047.0	-1753.0
IFNA8	1047.0	-1753.0
IGF2R	7820.0	-602.0
IGHV1-69	-7353.5	8845.5
IGHV2-5	4395.0	4965.0
IGHV2-70	4395.0	4965.0
IGHV7-81	517.5	7570.5
IGKC	-2925.0	7318.0
IGKV1-12	2052.5	4944.5
IGKV1-17	2052.5	4944.5
IGKV1-39	2052.5	4944.5
IGKV1D-12	2052.5	4944.5
IGKV1D-39	2052.5	4944.5
IGKV2-30	101.5	8396.5
IGKV2D-30	101.5	8396.5
IGKV4-1	-7301.0	8840.0
IGKV5-2	-5895.0	8671.0
IGLV4-60	-3537.5	3617.5
IGLV4-69	-3537.5	3617.5
IKBKB	-1785.0	-5829.0
IKBKE	2587.0	-6365.0
IKBKG	3700.0	-677.0
IL1B	-6242.0	3978.0
ILF2	2872.0	3070.0
IMPDH1	1190.0	4821.0
IMPDH2	4946.0	4658.0
IQGAP1	7427.0	8123.0
IQGAP2	8068.0	6890.0
IRAG2	-1956.0	-783.0
IRAK1	-3742.0	4800.0
IRAK2	-879.0	-1594.0
IRAK3	4675.0	4623.0
IRAK4	2339.0	4636.0
IRF3	806.0	-4184.0
IRF7	-4522.0	2058.0
ISG15	-1124.0	-2998.0
IST1	4515.0	-3732.0
ITCH	-4378.0	5792.0
ITGAL	-4315.0	-1137.0
ITGAM	3292.0	5515.0
ITGAV	8155.0	2693.0
ITGAX	-5859.0	2296.0
ITGB2	-5238.0	412.0
ITK	-3536.0	2982.0
ITPR1	-2727.0	2512.0
ITPR2	4185.0	-2206.0
ITPR3	7844.0	5234.0
JUN	581.0	5314.0
JUP	4751.0	2870.0
KCMF1	-2107.0	6464.0
KCNAB2	-1327.0	724.0
KLRC2	-2897.5	4049.5
KLRD1	-3689.0	-3816.0
KLRK1	-5741.0	7328.0
KPNB1	-1668.0	5829.0
KRAS	-752.0	8587.0
LAIR1	-5670.0	-3164.0
LAMP1	664.0	4209.0
LAMP2	-4970.0	6952.0
LAMTOR1	-81.0	-630.0
LAMTOR2	-2847.0	1280.0
LAMTOR3	2323.0	4870.0
LAT	1869.0	-481.0
LAT2	-2578.0	2305.0
LBP	4550.0	7403.0
LCK	-2194.0	5687.0
LCN2	5811.0	8293.0
LCP2	-5980.0	1266.0
LEAP2	2807.0	9.0
LGALS3	7090.0	5330.0
LGMN	7268.0	624.0
LILRB3	-7184.0	7732.0
LIMK1	3519.0	2264.0
LPCAT1	-6277.0	7035.0
LPO	5727.0	6892.0
LRG1	2288.0	4889.0
LRRC7	-883.0	-2663.0
LRRFIP1	5342.0	6570.0
LTA4H	-1869.0	3373.0
LTF	-2111.0	1638.0
LY86	-3524.0	1844.0
LY96	-4879.0	364.0
LYN	-4685.0	8216.0
MAGT1	-6822.0	7703.0
MALT1	-2981.0	1806.0
MAN2B1	-3804.0	-5934.0
MANBA	-5693.0	-5502.0
MAP2K1	7852.0	3274.0
MAP2K3	3494.0	-249.0
MAP2K4	2621.0	5572.0
MAP2K6	5640.0	-4115.0
MAP2K7	3505.0	-3383.0
MAP3K1	5322.0	-960.0
MAP3K14	-4228.0	558.0
MAP3K7	1594.0	7480.0
MAP3K8	656.0	2671.0
MAPK1	-3928.0	6920.0
MAPK10	-2089.0	-137.0
MAPK11	4349.0	2889.0
MAPK12	3182.0	6505.0
MAPK13	8059.0	5735.0
MAPK14	-6337.0	-1012.0
MAPK3	5390.0	5167.0
MAPK7	4710.0	-703.0
MAPK8	-3252.0	1695.0
MAPK9	2849.0	6624.0
MAPKAPK2	-2527.0	4587.0
MAPKAPK3	7267.0	-4297.0
MASP1	7705.0	8599.0
MASP2	-4240.0	-2143.0
MAVS	6937.0	-2375.0
MBL2	5539.0	-3910.0
MCEMP1	-5291.0	6726.0
MEF2A	-2071.0	7495.0
MEF2C	-1905.0	8451.0
MEFV	-4277.0	5186.0
METTL7A	1647.0	-266.0
MGAM	561.0	417.0
MGST1	7252.0	4639.0
MIF	8230.0	5317.0
MLEC	-7059.0	-620.0
MME	-2831.0	3783.0
MMP25	525.0	-6432.0
MMP9	-5717.0	1502.0
MNDA	-7345.0	8836.0
MOSPD2	-1998.0	8209.0
MPO	892.0	-1006.0
MRE11	-3060.0	3329.0
MS4A2	4446.0	3088.0
MUC1	7970.0	3179.0
MUC13	3695.0	1168.0
MUC19	-1591.0	-6413.0
MUC20	3931.0	5255.0
MUC3A	4383.0	638.0
MUC4	-846.0	-343.0
MUC5B	1330.0	-4558.0
MUC6	3660.0	-6706.0
MVP	6785.0	-5147.0
MYD88	-5933.0	3612.0
MYH9	7189.0	7115.0
MYO10	4745.0	-1478.0
MYO1C	7502.0	5436.0
MYO5A	-7077.0	3216.0
MYO9B	1982.0	-237.0
NAPRT	3730.0	-6610.0
NBEAL2	6989.0	-6392.0
NCF1	3710.0	-659.0
NCF2	-1972.0	-3232.0
NCF4	-5987.0	5579.0
NCK1	-4610.0	8438.0
NCKAP1	-5953.0	8521.0
NCKAP1L	-1592.0	4630.0
NCKIPSD	7238.0	-4983.0
NCSTN	6534.0	860.0
NDUFC2	4564.5	-5546.5
NEU1	-4896.0	-6581.0
NF2	215.0	5920.0
NFAM1	-5168.0	2355.0
NFASC	-6650.0	-793.0
NFATC1	6099.0	7170.0
NFATC2	4913.0	-5797.0
NFATC3	-5299.0	6496.0
NFKB1	5449.0	4035.0
NFKB2	2120.0	-4751.0
NFKBIA	1631.0	4830.0
NFKBIB	3850.0	467.0
NHLRC3	2688.0	-1139.0
NIT2	-5666.0	-1701.0
NKIRAS1	-5446.0	5927.0
NKIRAS2	7425.0	286.0
NLRC3	5548.0	-302.0
NLRC4	-6816.0	-2920.0
NLRC5	497.0	-5753.0
NLRP1	-3299.0	-5039.0
NLRP3	-5337.0	1863.0
NLRP4	2838.0	115.0
NLRX1	2674.0	-5541.0
NME2	-3826.0	-2887.0
NOD1	5283.0	4068.0
NOD2	-6286.0	2681.0
NOS1	6188.0	253.0
NOS2	-1104.0	4079.0
NOS3	1400.0	2054.0
NPC2	3922.0	3679.0
NRAS	3837.0	7903.0
OLFM4	6940.0	-1244.0
OLR1	-1782.0	2913.0
ORM1	3867.5	-4259.5
ORM2	3867.5	-4259.5
ORMDL3	5642.0	-2453.0
OSCAR	2024.0	-1438.0
OSTF1	6553.0	5854.0
OTUD5	-963.0	-1531.0
P2RX1	1145.0	5033.0
P2RX7	4651.0	4591.0
PA2G4	-2524.5	7069.5
PADI2	-2608.0	-2165.0
PAFAH1B2	-1657.0	7964.0
PAK1	-886.0	5458.0
PAK2	-4906.0	6708.0
PAK3	2878.0	1881.0
PANX1	-646.0	6554.0
PCBP2	6135.0	1313.0
PDAP1	3245.0	700.0
PDPK1	-4074.0	1936.0
PDXK	8266.0	-2949.0
PDZD11	-3180.0	64.0
PECAM1	3970.0	8677.0
PELI1	2295.0	5683.0
PELI2	4968.0	-157.0
PELI3	7915.0	-6062.0
PFKL	7340.0	-4515.0
PGAM1	1992.0	4530.0
PGLYRP1	-1223.0	-3101.0
PGLYRP2	-1116.0	-1352.0
PGM1	-1081.0	5048.0
PGM2	7401.0	7591.0
PGRMC1	8184.0	7942.0
PIGR	-1209.0	-4257.0
PIK3C3	1518.0	-2612.0
PIK3CA	-6347.0	2923.0
PIK3CB	-1756.0	1880.0
PIK3R1	-839.0	8363.0
PIK3R2	1669.5	-3969.5
PIK3R4	4272.0	-1214.0
PIN1	1926.0	-1497.0
PKM	7561.0	7758.0
PLA2G6	-5964.0	-5304.0
PLAC8	6334.0	-3893.0
PLAU	-5613.0	-5199.0
PLAUR	4004.0	6827.0
PLCG1	8067.0	-4962.0
PLCG2	-5287.0	2474.0
PLD1	-4824.0	-1222.0
PLD2	-309.0	-2778.0
PLD3	5879.0	-2713.0
PLD4	-6072.0	4205.0
PLEKHO2	-1522.5	7084.5
PLPP5	5578.0	-5435.0
PNP	-7335.0	8459.0
POLR1C	1437.0	-6049.0
POLR1D	-5146.0	4592.0
POLR2E	7128.0	-3504.0
POLR2F	6184.0	-3058.0
POLR2H	4359.0	-4161.0
POLR2K	1098.0	7632.0
POLR2L	3697.0	-3808.0
POLR3A	5281.0	-1328.0
POLR3B	107.0	1125.0
POLR3C	3514.0	4844.0
POLR3D	3066.0	-666.0
POLR3E	3631.0	-4589.0
POLR3F	-2723.0	6052.0
POLR3H	200.0	3724.0
POLR3K	-5432.0	6617.0
PPBP	-5336.0	4394.0
PPIA	4868.0	-469.0
PPIE	6275.0	-5627.0
PPP2CA	-5725.0	8237.0
PPP2CB	5588.0	159.0
PPP2R1A	6355.0	3115.0
PPP2R1B	-6463.0	4855.0
PPP2R5D	2088.0	5911.0
PPP3CA	5123.0	6939.0
PPP3CB	-1150.0	4729.0
PPP3R1	2835.5	8199.5
PRCP	-6663.0	1095.0
PRDX4	-68.0	-1128.0
PRDX6	-3287.0	3877.0
PRKACA	-530.0	15.0
PRKACB	569.0	661.0
PRKCD	365.0	1901.0
PRKCE	-5671.0	2371.0
PRKCQ	-2002.0	-3514.0
PRKCSH	-4469.0	-2597.0
PRKDC	-5092.0	3381.0
PROS1	4907.0	7279.0
PRSS2	-2444.0	-3110.0
PRSS3	-2444.0	-3110.0
PSAP	6220.0	-3472.0
PSEN1	-7020.0	6996.0
PSMA1	-6705.0	7838.0
PSMA2	-5464.5	6058.5
PSMA3	-3145.0	7801.0
PSMA4	-6074.0	4688.0
PSMA5	-6660.0	4497.0
PSMA6	-1954.0	8445.0
PSMA7	1612.0	7052.0
PSMA8	649.0	-4004.0
PSMB1	-5281.0	5936.0
PSMB10	3752.0	-908.0
PSMB11	1977.0	-5501.0
PSMB2	1472.0	-4144.0
PSMB3	-3388.0	5539.0
PSMB4	-4941.0	-5852.0
PSMB5	-1638.0	-2409.0
PSMB6	1806.0	-1845.0
PSMB7	-4628.0	-657.0
PSMB8	1080.0	-3793.0
PSMB9	5987.0	-4708.0
PSMC1	-1312.0	4327.0
PSMC2	-6765.0	4648.0
PSMC3	-4285.0	3386.0
PSMC4	-6423.0	7920.0
PSMC5	-4831.0	1120.0
PSMC6	-6851.0	8666.0
PSMD1	-6497.0	8619.0
PSMD10	-1613.0	2576.0
PSMD11	-6873.0	5201.0
PSMD12	-6149.0	8628.0
PSMD13	1898.0	5044.0
PSMD14	-6080.0	8262.0
PSMD2	-6702.0	-3836.0
PSMD3	-2532.0	-3242.0
PSMD4	-5648.0	4994.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
PSMD7	-6943.0	7625.0
PSMD8	1978.0	7546.0
PSMD9	7707.5	-894.5
PSME1	2907.0	5905.0
PSME2	1270.0	-4595.0
PSME3	752.0	7366.0
PSME4	-6830.0	8511.0
PSMF1	5087.0	4771.0
PSTPIP1	-1224.0	-988.0
PTAFR	-5062.0	6031.0
PTGES2	5575.0	-1828.0
PTK2	2264.0	6997.0
PTPN11	-3946.0	6142.0
PTPN4	-2725.0	7586.0
PTPN6	-1098.0	2140.0
PTPRB	3085.0	8717.0
PTPRC	-7112.0	6863.0
PTPRJ	3203.0	5737.0
PTPRN2	5657.0	877.0
PTX3	-4488.0	-2545.0
PYCARD	6548.0	-4704.0
PYGB	5808.0	5273.0
PYGL	6729.0	1748.0
QPCT	2060.0	2678.0
QSOX1	7456.0	1100.0
RAB10	-5609.0	8060.0
RAB14	-4203.0	5569.0
RAB18	-6358.0	6912.0
RAB24	4481.0	-5649.0
RAB27A	7997.0	1512.0
RAB31	3839.0	8541.0
RAB37	1244.0	-5646.0
RAB3A	-21.0	-1948.0
RAB3D	6472.0	4535.0
RAB4B	6400.5	-1765.5
RAB5B	5887.0	3206.0
RAB5C	3703.0	3375.0
RAB6A	-6370.0	8664.0
RAB7A	-5898.0	8083.0
RAC1	-1258.0	4008.0
RAC2	-3191.0	6081.0
RAF1	-6377.0	2465.0
RAP1A	-6787.0	8805.0
RAP1B	942.0	8759.0
RAP2B	5671.0	-1178.0
RAP2C	-4441.0	2874.0
RASGRP1	-370.0	-2734.0
RASGRP2	-326.0	-409.0
RASGRP4	-3063.0	1538.0
RBSN	-6349.0	6778.0
RELA	2579.0	-2368.0
RELB	4814.0	1355.0
RETN	-1704.0	-1106.0
RHOA	-5203.0	7671.0
RHOF	5184.0	-2496.0
RHOG	2039.0	1654.0
RIPK1	-2977.0	5088.0
RIPK2	5953.0	6306.0
RIPK3	1577.0	1519.0
RNASE2	5113.5	-4405.5
RNASE3	5113.5	-4405.5
RNASE6	-2529.0	1162.0
RNASET2	8101.5	-6540.5
RNF125	-4936.0	7540.0
RNF216	-840.0	5584.0
ROCK1	-2765.0	8654.0
RPS27A	-133.0	-1807.0
RPS6KA1	7703.0	4452.0
RPS6KA2	7237.0	-2956.0
RPS6KA3	-6111.0	8270.0
RPS6KA5	2516.0	-3206.0
S100A1	1975.0	8367.0
S100A11	4838.0	7913.0
S100A8	-3981.0	6893.0
S100B	1781.0	-995.0
SARM1	2160.0	336.0
SCAMP1	7264.0	2855.0
SDCBP	5668.0	4540.0
SELL	-4022.0	902.0
SERPINA1	8234.0	4905.0
SERPINA3	2345.0	8095.0
SERPINB1	7293.0	4143.0
SERPINB10	4371.0	-319.0
SERPINB6	7950.0	8360.0
SERPING1	3751.0	8403.0
SHC1	568.0	1962.0
SIGIRR	-826.0	-4627.0
SIGLEC9	-2039.5	-2039.5
SIKE1	2817.0	3211.0
SIRPA	-6193.5	-6693.5
SIRPB1	-6193.5	-6693.5
SKP1	-6803.0	8394.0
SLC11A1	-1742.0	815.0
SLC15A4	-6120.0	-5883.0
SLC27A2	-6940.0	532.0
SLC2A5	8118.0	4882.0
SLC44A2	7940.0	4899.0
SLCO4C1	1461.0	-992.0
SLPI	307.0	3136.0
SNAP23	-6477.0	8059.0
SNAP29	-7150.0	7785.0
SOCS1	-253.0	-5520.0
SOS1	-6566.0	7698.0
SPTAN1	7051.0	7359.0
SRC	-2657.0	-1643.0
SRP14	372.0	5948.0
STAT6	-6946.0	2330.0
STBD1	-6692.0	3728.0
STING1	-266.0	6780.0
STK10	-1779.0	2392.0
STK11IP	7069.0	-5659.0
STOM	2062.0	8033.0
SUGT1	3448.0	6681.0
SURF4	-5939.0	2804.0
SVIP	-1801.0	4362.0
SYK	-6921.0	4480.0
SYNGR1	6225.0	-2427.0
TAB1	7839.0	-5339.0
TAB2	-7040.0	7307.0
TAB3	3966.0	5424.0
TANK	-4899.0	6416.0
TARM1	6276.0	2422.0
TAX1BP1	3157.0	7948.0
TBC1D10C	4785.0	-3612.0
TBK1	-5003.0	4897.0
TCIRG1	-5363.0	-3931.0
TEC	-5516.0	6783.0
TICAM1	-1539.0	-3874.0
TIFA	2278.0	5664.0
TIMP2	4104.0	8646.0
TIRAP	-3143.0	6369.0
TKFC	5898.0	1211.0
TLR1	-3224.0	560.0
TLR2	5407.0	5188.0
TLR3	1181.0	6018.0
TLR4	-4128.0	8470.0
TLR6	-4778.0	7142.0
TLR7	-3743.0	5769.0
TLR8	281.0	6768.0
TLR9	-3935.5	846.5
TMBIM1	5555.0	2568.0
TMC6	-5597.0	-5013.0
TMEM179B	-3249.0	-2550.0
TMEM30A	-6557.0	6632.0
TMEM63A	7912.0	1.0
TNFAIP3	-151.0	2986.0
TNFAIP6	-3592.0	4376.0
TNFRSF1B	-5427.0	939.0
TNIP2	7153.0	-6672.0
TOLLIP	5721.0	3964.0
TOM1	-2514.0	-174.0
TRAF2	3405.0	-3806.0
TRAF3	-6416.0	5442.0
TRAF6	1082.0	6626.0
TRAPPC1	-1429.0	4746.0
TREM1	169.0	-2242.0
TREM2	-4021.0	2867.0
TREX1	1252.0	2779.0
TRIM21	344.0	-452.0
TRIM25	-5042.0	-3205.0
TRIM32	-6017.0	-3715.0
TRIM56	-728.0	-4103.0
TRPM2	-2904.0	-6037.0
TSPAN14	-6627.0	1158.0
TTR	-6090.0	3451.0
TUBB	335.0	8036.0
TUBB4B	-5222.0	8679.0
TXK	861.0	-4279.0
TXN	-5397.0	-2909.0
TXNDC5	1391.0	-669.0
TXNIP	2986.0	4021.0
TYROBP	-4245.0	2276.0
UBA3	-3218.0	8194.0
UBA52	7488.0	-4269.0
UBA7	-3088.0	-3909.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
UBE2D1	5638.0	3025.0
UBE2D2	-935.0	6690.0
UBE2D3	-5084.0	8317.0
UBE2K	-3148.0	7485.0
UBE2L6	809.0	5322.0
UBE2M	3424.0	2257.0
UBR4	4082.0	-4874.0
UNC13D	12.0	-5070.0
UNC93B1	-2571.0	-565.0
VAMP8	-3005.0	5301.0
VAPA	-4422.0	7382.0
VAT1	7581.0	-4263.0
VAV1	-4395.0	5076.0
VAV2	2432.0	-843.0
VAV3	6942.0	5027.0
VCL	-4796.0	7947.0
VCP	-7069.0	5449.0
VNN1	6246.0	7250.0
VPS35L	968.0	-5964.0
VRK3	-4442.0	-4059.0
WAS	-11.0	299.0
WASF1	-5233.0	-3651.0
WASF2	4804.0	1618.0
WASF3	4712.0	680.0
WASL	-3989.0	7855.0
WIPF1	-3718.0	7829.0
WIPF2	4034.0	-1247.0
WIPF3	7332.0	3435.0
XRCC5	-2388.0	162.0
XRCC6	-1971.0	4034.0
YES1	-120.0	7265.0
YPEL5	8001.0	3939.0
ZBP1	-6151.0	4520.0

---

---

Vesicle-mediated transport

Vesicle-mediated transport

metric	value
setSize	622
pMANOVA	2.63e-17
p.adjustMANOVA	5.27e-15
s.dist	0.215
s.diabetes	-0.0629
s.mitoG	0.205
p.diabetes	0.00776
p.mitoG	3.39e-18

Top 20 genes

Gene	diabetes	mitoG
IGHV1-69	-7353.5	8845.5
IGKV4-1	-7301.0	8840.0
HSP90AA1	-7286.0	8742.0
HSP90B1	-7279.0	8368.0
HSPA8	-7307.0	8180.0
UBB	-7104.0	8341.0
CAPZA1	-6942.0	8474.0
USO1	-6682.0	8749.0
SNAP29	-7150.0	7785.0
RAB6A	-6370.0	8664.0
ARCN1	-6138.0	8768.0
SEC24D	-6384.0	8428.0
TRIP11	-6424.0	8302.0
DYNLL1	-6952.0	7645.0
VPS54	-6687.0	7941.0
PICALM	-6252.0	8380.0
SNAP23	-6477.0	8059.0
RAB1A	-6571.0	7889.0
M6PR	-7125.0	7218.0
UBC	-6013.0	8514.0

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
AAK1	883.0	56.0
ACBD3	-2828.0	5524.0
ACTR10	268.0	6666.0
ACTR1A	965.0	5035.0
ACTR2	-5189.0	7356.0
ACTR3	-3716.0	8206.0
ADRB2	-6910.0	4340.0
AGFG1	-3918.0	7468.0
AGPAT3	-4447.0	-444.0
AGTR1	-3186.0	4400.0
AKT1	4859.0	7244.0
AKT2	-4939.0	3281.0
AKT3	-375.0	7862.0
ALB	6253.0	-380.0
ALS2	-6333.0	910.0
ALS2CL	4251.0	-5644.0
AMBP	4518.0	-3879.0
AMPH	-1364.0	554.0
ANK1	-2384.0	4523.0
ANK2	6760.0	923.0
ANK3	-300.0	4794.0
ANKRD27	1587.0	-3284.0
ANKRD28	8017.0	7539.0
AP1B1	5867.0	-3224.0
AP1G1	-6928.0	3255.0
AP1G2	-1203.0	-5382.0
AP1M1	2796.0	-3928.0
AP1M2	7170.0	-121.0
AP1S1	-667.0	-1428.0
AP1S2	-2308.0	7787.0
AP1S3	483.0	-6543.0
AP2A1	3192.0	-2941.0
AP2A2	-6231.0	249.0
AP2B1	-3990.0	7426.0
AP2M1	5073.0	2926.0
AP2S1	587.0	7094.0
AP3B1	3159.0	1998.0
AP3S1	-4458.0	6712.0
AP4B1	-5531.0	-776.0
AP4E1	-2091.0	-4473.0
AP4M1	2093.0	-5788.0
AP4S1	2217.0	1812.0
APOA1	3682.0	-305.0
APOB	7604.0	5782.0
APOE	5835.0	342.0
APOL1	-5660.5	2701.5
APP	-5115.0	6758.0
ARCN1	-6138.0	8768.0
ARF1	-5273.0	7470.0
ARF3	4831.5	-5103.5
ARF4	-6276.0	6071.0
ARF5	5403.0	222.0
ARF6	-804.0	229.0
ARFGAP1	-1727.0	-5894.0
ARFGAP2	5632.0	-3320.0
ARFGAP3	-1901.0	5934.0
ARFIP2	-3761.0	6326.0
ARFRP1	702.0	-6512.0
ARL1	-4284.0	8747.0
ARPC1A	-1009.0	-3070.0
ARPC2	-4512.0	8767.0
ARPC3	-5747.0	8757.0
ARPC4	3077.0	1525.0
ARPC5	920.0	7514.0
ARRB1	-6250.0	3030.0
ARRB2	-3644.0	681.0
ASPSCR1	-1896.0	1206.0
AVPR2	4980.0	2853.0
BET1L	2662.0	-5180.0
BICD1	-2065.0	6371.0
BICD2	-1620.0	4239.0
BIN1	-3934.0	-213.0
BLOC1S1	-6342.5	-164.5
BLOC1S3	-2239.0	-3153.0
BLOC1S4	-4206.0	-3968.0
BLOC1S6	-2843.0	6751.0
BNIP1	-2171.0	1583.0
BTC	7701.0	1951.0
C2CD5	6584.0	-6499.0
CALM1	-4401.0	8702.0
CALR	-7105.0	5809.0
CAPZA1	-6942.0	8474.0
CAPZA2	-1687.0	8135.0
CAPZB	-2513.0	7203.0
CBL	-6462.0	4306.0
CCZ1	2495.5	3096.5
CCZ1B	2495.5	3096.5
CD163	-2470.0	7418.0
CD36	-7328.0	6006.0
CD3D	-3626.0	-15.0
CD3G	-1784.0	-3919.0
CD4	409.0	5008.0
CD55	-6863.0	6749.0
CD59	5509.5	-1796.5
CENPE	1973.0	460.0
CFTR	-6902.0	4865.0
CHM	-4490.0	8464.0
CHML	1162.0	5630.0
CHMP2A	3891.0	6246.0
CHMP2B	-3672.0	8606.0
CHMP3	-5181.5	8584.5
CHMP4B	7103.0	2636.0
CHMP4C	6678.0	1533.0
CHMP5	-4004.0	8542.0
CHMP6	4209.0	-2043.0
CHMP7	-57.0	-2549.0
CLINT1	-5244.0	4684.0
CLTA	-2807.0	2774.0
CLTB	4559.0	6461.0
CLTC	-4493.0	8248.0
CLVS1	-3816.0	2630.0
CLVS2	5315.0	-4006.0
CNIH1	-3991.0	8144.0
CNIH2	-2187.0	-4202.0
CNIH3	282.0	-4450.0
COG1	6605.0	-5589.0
COG2	549.0	4121.0
COG3	-5097.0	5605.0
COG4	1502.0	-5457.0
COG5	-2281.0	6788.0
COG6	-4517.0	730.0
COG7	6910.0	3017.0
COL1A1	112.0	2092.0
COL1A2	416.0	5053.0
COL3A1	-2073.0	3836.0
COL4A1	-1913.0	7738.0
COL4A2	5885.0	8130.0
COLEC11	631.0	3003.0
COLEC12	190.0	8600.0
COPA	488.0	2943.0
COPB1	-2848.0	7946.0
COPB2	-4259.0	8427.0
COPE	1600.0	4567.0
COPG1	-3891.0	3599.0
COPG2	2511.0	4641.0
COPS2	-5385.0	8716.0
COPS3	-904.0	8468.0
COPS4	-2811.0	8111.0
COPS5	430.0	6558.0
COPS6	1528.0	28.0
COPS7A	5878.0	-2436.0
COPS7B	-2394.0	-5916.0
COPS8	-147.0	1724.0
COPZ1	-4248.0	-67.0
COPZ2	3609.0	1137.0
CPD	5871.0	4487.0
CSNK1D	-1602.0	2506.0
CTSC	-1974.0	7696.0
CTSZ	-2861.0	2478.0
CTTN	211.0	2434.0
CUX1	-7126.0	4438.0
CYTH1	7147.0	5138.0
CYTH2	577.0	-1256.0
CYTH3	6160.0	6650.0
CYTH4	-6038.0	-2841.0
DAB2	-5689.0	1606.0
DCTN1	7218.0	-3098.0
DCTN2	2623.0	-2017.0
DCTN3	-715.0	689.0
DCTN4	-4133.0	7527.0
DCTN5	-4033.0	5094.0
DCTN6	4374.0	7565.0
DENND1A	-3578.0	-3992.0
DENND1B	-3640.0	6236.0
DENND1C	-4020.0	-3509.0
DENND2A	3171.0	5959.0
DENND2C	1598.0	3103.0
DENND2D	3945.0	-4019.0
DENND3	6819.0	-3851.0
DENND4A	7387.0	7310.0
DENND4B	5161.0	-4355.0
DENND4C	-5667.0	856.0
DENND5A	-6788.0	7092.0
DENND5B	-4587.0	3208.0
DENND6A	-3417.0	7381.0
DENND6B	3023.0	-6519.0
DNAJC6	6110.0	-873.0
DNASE2	-2379.0	-2179.0
DNM1	7171.0	3067.0
DNM2	-1598.0	5364.0
DNM3	6014.0	942.0
DTNBP1	6735.0	5583.0
DVL2	7754.0	-6212.0
DYNC1H1	4822.0	2594.0
DYNC1I1	3045.0	-5230.0
DYNC1I2	-251.0	7398.0
DYNC1LI1	2249.0	7292.0
DYNC1LI2	-1436.0	1861.0
DYNLL1	-6952.0	7645.0
DYNLL2	4932.0	-5028.0
EGF	-4765.0	-210.0
EGFR	-6023.0	1902.0
EPN1	-1121.0	-4468.0
EPN2	5737.0	3940.0
EPS15	-5197.0	5904.0
EPS15L1	3879.0	-4887.0
EXOC1	-2979.0	-335.0
EXOC2	7117.0	-1912.0
EXOC3	-5362.0	5791.0
EXOC4	7198.0	5527.0
EXOC5	-2682.0	8595.0
EXOC6	-6197.0	3478.0
EXOC7	2029.0	3647.0
EXOC8	-1501.0	-3511.0
F5	-5716.0	-1378.0
F8	-688.0	7499.0
FCHO1	3015.0	1348.0
FCHO2	6592.0	5417.0
FNBP1	-4982.0	-2153.0
FNBP1L	3122.0	4349.0
FOLR1	-6908.0	-283.0
FTL	-6693.0	-6771.0
FZD4	6121.0	5562.0
GABARAP	-5579.0	8282.0
GABARAPL2	-1204.0	2829.0
GAK	-4211.0	5123.0
GALNT1	-6827.0	6806.0
GALNT2	-4331.0	2581.0
GAPVD1	-4780.0	2418.0
GBF1	-6681.0	3356.0
GCC1	3057.0	524.0
GCC2	-3855.0	7972.0
GDI1	2238.0	3292.0
GDI2	-5894.0	8074.0
GGA1	-539.0	-4988.0
GGA2	2677.0	-3451.0
GGA3	-3482.0	-6019.0
GJA1	-2103.0	-4151.0
GJA3	1739.0	-2907.0
GJA4	7104.0	-3166.0
GJA5	1705.0	2064.0
GJA8	1944.0	-1336.0
GJB1	-2164.0	2821.0
GJB2	-4828.0	3699.0
GJB3	-2101.0	4605.0
GJB6	5153.0	-297.0
GJC1	-360.0	8269.0
GJC2	1990.0	3378.0
GJD3	4989.0	129.0
GJD4	3782.0	-1724.0
GNS	8072.0	1691.0
GOLGA1	-6570.0	3706.0
GOLGA4	-3479.0	-714.0
GOLGA5	746.0	8085.0
GOLGB1	-4541.0	3630.0
GOLIM4	-2600.0	7173.0
GORASP1	1404.0	-5586.0
GOSR1	2520.0	5197.0
GOSR2	-4613.5	7118.5
GPS1	-1275.0	3233.0
GRB2	3285.0	1922.0
GRIA1	3840.0	-983.0
GRK2	-1123.0	7008.0
GRK3	-2167.0	-104.0
HBA1	5772.5	8630.5
HBEGF	-6694.0	-80.0
HGS	-1920.0	704.0
HIP1	1316.0	7975.0
HIP1R	7828.0	-2141.0
HP	-1369.5	6104.5
HPR	-1369.5	6104.5
HPS1	2385.0	-4872.0
HPS4	7159.0	-6710.0
HPX	2769.0	2190.0
HSP90AA1	-7286.0	8742.0
HSP90B1	-7279.0	8368.0
HSPA8	-7307.0	8180.0
HSPH1	-7334.0	5252.0
HYOU1	-7255.0	4009.0
IGF2R	7820.0	-602.0
IGHA1	-5036.5	7384.5
IGHA2	-5036.5	7384.5
IGHV1-69	-7353.5	8845.5
IGHV2-5	4395.0	4965.0
IGHV2-70	4395.0	4965.0
IGHV7-81	517.5	7570.5
IGKC	-2925.0	7318.0
IGKV1-12	2052.5	4944.5
IGKV1-17	2052.5	4944.5
IGKV1-39	2052.5	4944.5
IGKV1D-12	2052.5	4944.5
IGKV1D-39	2052.5	4944.5
IGKV2-30	101.5	8396.5
IGKV2D-30	101.5	8396.5
IGKV4-1	-7301.0	8840.0
IGKV5-2	-5895.0	8671.0
IGLV4-60	-3537.5	3617.5
IGLV4-69	-3537.5	3617.5
IL7R	-5696.0	8026.0
ITSN1	-2643.0	3175.0
ITSN2	-5674.0	5013.0
JCHAIN	-1963.0	6913.0
KDELR1	-5082.0	-3141.0
KDELR2	-4969.0	8520.0
KDELR3	3008.0	2539.0
KIAA0319	1289.0	-5453.0
KIF11	4262.0	-1098.0
KIF12	-3419.0	-6372.0
KIF13B	6407.0	-5191.0
KIF15	91.0	-5193.0
KIF16B	-2844.0	3593.0
KIF18A	-2035.0	4687.0
KIF18B	4824.0	632.0
KIF19	1923.0	-4963.0
KIF1A	5374.0	5302.0
KIF1B	2260.0	5141.0
KIF1C	-812.0	669.0
KIF20A	3022.0	-1094.0
KIF20B	-7215.0	5043.0
KIF21A	-5621.0	7768.0
KIF21B	1267.0	-2504.0
KIF22	-925.0	-1002.0
KIF23	6834.0	-2775.0
KIF26A	3470.0	3765.0
KIF26B	6327.0	-720.0
KIF27	-5722.0	1135.0
KIF2A	1251.0	7652.0
KIF2C	2591.0	-1946.0
KIF3A	-5126.0	3351.0
KIF3B	-3223.0	6725.0
KIF3C	-3455.0	5074.0
KIF4A	1014.0	6024.0
KIF5A	-5260.0	-5278.0
KIF5B	-1547.0	8819.0
KIF5C	6290.0	2117.0
KIF6	5572.0	-4169.0
KIF9	55.0	-2135.0
KIFAP3	41.0	8075.0
KIFC1	8091.0	-6629.0
KIFC2	5216.0	-6709.0
KLC1	143.0	-5336.0
KLC2	6949.0	-4707.0
KLC3	7232.0	-1031.0
KLC4	-6395.0	-2860.0
LDLR	4229.0	3193.0
LDLRAP1	6322.0	5636.0
LMAN1	-4772.0	8101.0
LMAN2	-6960.0	209.0
LMAN2L	-6950.0	-4458.0
LNPEP	4116.0	7467.0
LRP1	7344.0	8465.0
LRP2	-7179.0	-3908.0
M6PR	-7125.0	7218.0
MADD	-4200.0	-2939.0
MAN1A1	-4332.0	3367.0
MAN1A2	-1067.0	6604.0
MAN1C1	6879.0	7174.0
MAN2A1	8162.0	5453.0
MAN2A2	-1276.0	3170.0
MAP1LC3B	3858.5	3812.5
MASP1	7705.0	8599.0
MCFD2	-4954.0	6881.0
MIA2	-5486.0	8570.0
MON1A	-1003.0	-43.0
MON1B	2133.0	-4380.0
MSR1	336.0	3428.0
MVB12A	5433.0	3851.0
MVB12B	-659.0	-5360.0
MYH9	7189.0	7115.0
MYO1C	7502.0	5436.0
MYO5A	-7077.0	3216.0
MYO6	-5300.0	6176.0
NAA30	-1919.0	4544.0
NAA35	22.0	260.0
NAA38	-4146.0	-1683.0
NAPA	5425.0	1632.0
NAPB	2953.0	-4029.0
NAPG	3323.0	2180.0
NBAS	-6309.0	-4474.0
NECAP1	-79.0	5214.0
NECAP2	4045.0	1923.0
NEDD8	-4578.0	7681.0
NSF	4215.0	7420.0
OCRL	3974.0	593.0
OPTN	8052.0	6703.0
PACSIN1	1585.0	2292.0
PACSIN2	7548.0	3572.0
PACSIN3	7735.0	-4476.0
PAFAH1B1	-3995.0	8266.0
PAFAH1B2	-1657.0	7964.0
PAFAH1B3	4821.0	-71.0
PICALM	-6252.0	8380.0
PIK3C2A	-262.0	8592.0
PIP5K1C	6778.0	694.0
PLA2G4A	7058.0	5276.0
PLA2G6	-5964.0	-5304.0
PLIN3	5004.0	-4323.0
POLG	754.0	-4942.0
PPP6C	1874.0	5889.0
PPP6R1	-4706.0	-2647.0
PPP6R3	-5114.0	7597.0
PREB	-6991.0	-1923.0
PRKAA2	-1063.0	2375.0
PRKAB1	7696.0	1290.0
PRKAB2	4730.0	-4503.0
PRKAG1	1680.0	-288.0
PRKAG2	7790.0	-3443.0
PRKAG3	5892.0	-1774.0
PUM1	-856.0	-3002.0
RAB10	-5609.0	8060.0
RAB11A	-3713.0	8250.0
RAB11B	4309.0	4748.0
RAB12	-1057.0	8176.0
RAB13	3302.5	1698.5
RAB14	-4203.0	5569.0
RAB18	-6358.0	6912.0
RAB1A	-6571.0	7889.0
RAB1B	-80.0	-4574.0
RAB21	-2903.0	7574.0
RAB27A	7997.0	1512.0
RAB27B	-4838.0	5533.0
RAB30	6435.0	5622.0
RAB31	3839.0	8541.0
RAB33B	2372.0	6149.0
RAB35	-1301.0	5850.0
RAB36	690.0	-5670.0
RAB38	-6913.0	3044.0
RAB39A	-2191.0	1676.0
RAB39B	-1021.0	6431.0
RAB3A	-21.0	-1948.0
RAB3GAP1	1288.0	3646.0
RAB3GAP2	1771.0	-2399.0
RAB3IL1	-6837.0	-1600.0
RAB43	8116.0	1573.0
RAB4A	-4186.0	1766.0
RAB5A	1537.0	7332.0
RAB5B	5887.0	3206.0
RAB5C	3703.0	3375.0
RAB6A	-6370.0	8664.0
RAB6B	7529.0	1278.0
RAB7A	-5898.0	8083.0
RAB7B	-5496.0	5451.0
RAB8A	-855.0	2596.0
RAB8B	3129.0	7133.0
RAB9A	-412.0	7818.0
RABEP1	-1962.0	2952.0
RABEPK	2166.0	960.0
RABGAP1	-2389.0	6981.0
RABGEF1	5972.0	6956.0
RAC1	-1258.0	4008.0
RACGAP1	6146.0	-2445.0
RALA	-5149.0	6748.0
RALGAPA2	4862.0	2010.0
RALGAPB	-6085.0	4766.0
REPS1	1567.0	6807.0
REPS2	-6894.0	6233.0
RGP1	6921.0	-4505.0
RHOBTB3	7579.0	5682.0
RHOQ	7462.0	6211.0
RIC1	1268.0	5479.0
RIN1	3110.0	1704.0
RIN2	-2547.0	4612.0
RIN3	-4871.0	-311.0
RINL	-6388.0	-1892.0
RINT1	-2729.0	-5208.0
RPS27A	-133.0	-1807.0
SAR1B	-3423.0	7668.0
SBF1	5827.0	-6278.0
SBF2	7073.0	3902.0
SCARA5	5837.0	696.0
SCARB1	2415.0	4827.0
SCARB2	6376.0	7312.0
SCARF1	4977.0	-975.0
SCFD1	-5793.0	7896.0
SCOC	-2294.0	8643.0
SEC13	-1432.0	3604.0
SEC16A	-1511.0	3230.0
SEC16B	8007.0	2261.0
SEC22A	3566.0	5061.0
SEC22B	-4623.0	5601.0
SEC22C	5970.0	-5637.0
SEC23A	-3552.0	8413.0
SEC23IP	-1834.0	5924.0
SEC24A	159.0	5121.0
SEC24B	-570.0	-3344.0
SEC24C	-5965.0	-1916.0
SEC24D	-6384.0	8428.0
SEC31A	835.0	-552.0
SERPINA1	8234.0	4905.0
SFN	3916.0	5704.0
SGIP1	6996.0	-6306.0
SH3D19	-6654.0	1762.0
SH3GL1	993.0	-4650.0
SH3GL2	-6503.0	867.0
SH3KBP1	3805.0	5866.0
SLC2A4	8055.0	-2624.0
SLC2A8	8092.0	-6699.0
SNAP23	-6477.0	8059.0
SNAP29	-7150.0	7785.0
SNAP91	4566.0	3611.0
SNAPIN	2078.0	4336.0
SNF8	2397.0	-3270.0
SNX18	413.0	18.0
SNX2	-4579.0	8581.0
SNX5	998.0	8207.0
SNX9	3993.0	5456.0
SORT1	6873.0	3383.0
SPARC	6297.0	8700.0
SPTA1	-2878.0	4811.0
SPTAN1	7051.0	7359.0
SPTB	7834.0	-4096.0
SPTBN1	4136.0	7630.0
SPTBN2	7922.0	-2952.0
SPTBN5	4733.0	-1695.0
SRC	-2657.0	-1643.0
SSC5D	4955.0	-2682.0
STAB1	8142.0	4360.0
STAB2	3055.0	-2320.0
STAM	-2360.0	4932.0
STAM2	494.0	2564.0
STON1	3948.5	7204.5
STON2	2271.0	1103.0
STX16	-6431.5	-5194.5
STX17	4886.0	-671.0
STX18	-6160.0	5652.0
STX4	-3184.0	-4491.0
STX5	-4974.0	-4939.0
STX6	2498.0	2382.0
STXBP3	728.0	7644.0
SURF4	-5939.0	2804.0
SYNJ1	2013.0	4478.0
SYNJ2	3594.0	6905.0
SYT1	-2989.0	-4969.0
SYT11	727.0	3892.0
SYT2	-2226.0	-4027.0
SYT9	5485.0	1871.0
SYTL1	5660.0	-4878.0
TACR1	-1916.0	-1112.0
TBC1D1	83.0	8056.0
TBC1D10A	-3577.0	-5886.0
TBC1D10B	-4687.0	-4211.0
TBC1D10C	4785.0	-3612.0
TBC1D13	-5658.0	-4914.0
TBC1D14	2183.0	2622.0
TBC1D15	1925.0	6934.0
TBC1D16	8187.0	-3920.0
TBC1D17	6335.0	-6244.0
TBC1D2	7607.0	-1821.0
TBC1D20	1958.0	574.0
TBC1D24	4169.5	-1717.5
TBC1D25	-3737.0	-1337.0
TBC1D4	3817.0	1800.0
TBC1D7	-136.0	3571.0
TBC1D8B	-6069.0	8127.0
TF	6988.0	4696.0
TFG	-5471.0	5860.0
TFRC	-4827.0	4702.0
TGFA	4979.0	2380.0
TGOLN2	-6334.0	4798.0
TJP1	4021.0	8531.0
TMED10	-6147.0	6432.0
TMED2	-2351.0	6953.0
TMED3	-6313.0	3992.0
TMED7	-4902.5	7760.5
TMED9	-5309.0	-1036.0
TMEM115	1699.0	-4432.0
TMF1	-1973.0	8658.0
TOR1A	-1140.0	6598.0
TOR1B	4430.0	17.0
TPD52	-2660.5	6366.5
TPD52L1	2889.0	7584.0
TRAPPC1	-1429.0	4746.0
TRAPPC10	2000.0	2916.0
TRAPPC11	1264.0	6074.0
TRAPPC12	6523.0	-3711.0
TRAPPC13	-5406.0	5577.0
TRAPPC2	-3263.0	6403.0
TRAPPC2L	3633.0	-4527.0
TRAPPC3	593.0	5718.0
TRAPPC4	-1321.0	-410.0
TRAPPC5	-2311.0	-1472.0
TRAPPC6A	7806.0	-5370.0
TRAPPC6B	978.0	7705.0
TRAPPC8	-6092.0	7767.0
TRAPPC9	1611.0	-4039.0
TRIP10	6118.0	-2284.0
TRIP11	-6424.0	8302.0
TSC1	6280.0	-2516.0
TSC2	5344.0	-2751.0
TSG101	-708.0	7980.0
TXNDC5	1391.0	-669.0
UBA52	7488.0	-4269.0
UBAP1	-6158.0	7653.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
UBQLN1	-6727.0	6938.0
UBQLN2	1361.0	868.0
ULK1	7107.0	-1830.0
USE1	3688.0	-3547.0
USO1	-6682.0	8749.0
USP6NL	5290.0	6675.0
VAMP2	8086.5	-3275.5
VAMP3	1693.0	5955.0
VAMP4	-908.0	852.0
VAMP8	-3005.0	5301.0
VPS25	-306.0	6834.0
VPS28	4871.0	5243.0
VPS36	5728.0	8042.0
VPS37A	-5968.0	8308.0
VPS37B	5639.0	2161.0
VPS37C	5395.0	-224.0
VPS37D	-1556.0	-3123.0
VPS45	-788.0	4784.0
VPS4A	-5731.5	7213.5
VPS4B	2398.0	6175.0
VPS51	3048.0	-6458.0
VPS52	-3308.0	-5643.0
VPS53	424.0	7261.0
VPS54	-6687.0	7941.0
VTA1	-2777.0	104.0
VTI1A	-1225.0	3613.0
WASL	-3989.0	7855.0
WNT5A	5498.0	-739.0
YIPF6	-4393.0	6442.0
YKT6	2462.0	3655.0
YWHAB	-4723.0	8579.0
YWHAE	-2079.0	7315.0
YWHAG	-5348.0	1700.0
YWHAH	-6051.0	7949.0
YWHAQ	3046.0	8675.0
YWHAZ	-5614.0	8512.0
ZW10	-6443.0	-752.0

---

---

Adaptive Immune System

Adaptive Immune System

metric	value
setSize	663
pMANOVA	3.43e-17
p.adjustMANOVA	6.01e-15
s.dist	0.219
s.diabetes	-0.141
s.mitoG	0.167
p.diabetes	6.49e-10
p.mitoG	2.84e-13

Top 20 genes

Gene	diabetes	mitoG
IGHV1-69	-7353.5	8845.5
IGKV4-1	-7301.0	8840.0
RAP1A	-6787.0	8805.0
PSMC6	-6851.0	8666.0
UBB	-7104.0	8341.0
CANX	-6936.0	8532.0
CAPZA1	-6942.0	8474.0
PSME4	-6830.0	8511.0
UBE2E1	-6831.0	8405.0
SKP1	-6803.0	8394.0
PDIA3	-7283.0	7821.0
PSMD1	-6497.0	8619.0
LILRA4	-7184.0	7732.0
LILRA5	-7184.0	7732.0
LILRA6	-7184.0	7732.0
LILRB3	-7184.0	7732.0
LILRB5	-7184.0	7732.0
HSPA5	-7309.0	7589.0
KLHL2	-6669.0	8214.0
ITGB1	-6241.0	8758.0

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
ACTR10	268.0	6666.0
ACTR1A	965.0	5035.0
ACTR1B	1842.0	570.0
AHCYL1	-5585.0	5114.0
AKT1	4859.0	7244.0
AKT2	-4939.0	3281.0
AKT3	-375.0	7862.0
ANAPC1	-6298.0	2903.0
ANAPC10	-1783.0	4951.0
ANAPC13	-4345.0	4356.0
ANAPC2	-3336.0	-4659.0
ANAPC4	6315.0	5808.0
ANAPC5	6285.0	-1473.0
ANAPC7	5249.0	-3454.0
AP1B1	5867.0	-3224.0
AP1G1	-6928.0	3255.0
AP1M1	2796.0	-3928.0
AP1M2	7170.0	-121.0
AP1S1	-667.0	-1428.0
AP1S2	-2308.0	7787.0
AP1S3	483.0	-6543.0
AP2A1	3192.0	-2941.0
AP2A2	-6231.0	249.0
AP2B1	-3990.0	7426.0
AP2M1	5073.0	2926.0
AP2S1	587.0	7094.0
AREL1	-3567.0	4170.0
ARF1	-5273.0	7470.0
ARIH2	7119.0	4936.0
ASB1	5747.0	-5391.0
ASB11	8005.0	3354.0
ASB13	-4592.0	5233.0
ASB14	4009.0	1161.0
ASB15	2791.0	-2241.0
ASB16	-285.0	-261.0
ASB18	-1279.0	-1197.0
ASB2	-4035.0	3690.0
ASB3	-3110.0	1156.0
ASB4	2909.0	2350.0
ASB5	1025.0	-247.0
ASB6	2948.0	-2420.0
ASB7	4873.0	2631.0
ASB8	-2617.0	6851.0
ASB9	-6461.0	6880.0
ATG7	7859.0	-906.0
B2M	5339.0	4978.0
BCL10	-3598.0	5942.0
BLMH	646.0	1455.0
BLNK	6748.0	-965.0
BTBD1	-5007.0	8727.0
BTBD6	2905.0	-1931.0
BTK	-5279.0	5486.0
BTLA	-4363.0	5386.0
BTN3A1	-3969.0	4770.0
BTNL9	-6257.0	5075.0
BTRC	3218.0	-5334.0
C3	7675.0	3404.0
CALM1	-4401.0	8702.0
CALR	-7105.0	5809.0
CANX	-6936.0	8532.0
CAPZA1	-6942.0	8474.0
CAPZA2	-1687.0	8135.0
CAPZB	-2513.0	7203.0
CARD11	-3020.0	3028.0
CBLB	-3155.0	5963.0
CCNF	4264.0	-2470.0
CD101	-4774.0	2308.0
CD14	4081.0	6994.0
CD160	688.0	2601.0
CD19	-2666.0	-3652.0
CD1D	5611.0	119.0
CD200	5072.0	7059.0
CD200R1	-6039.5	6134.5
CD209	-6793.0	-6525.0
CD22	-4125.0	1554.0
CD226	-3734.0	272.0
CD247	1213.0	-5666.0
CD274	-1627.0	306.0
CD28	-4408.0	5134.0
CD300A	-4313.5	171.5
CD300C	-3410.0	2113.0
CD300E	3256.0	-126.0
CD300LB	-758.0	-39.0
CD300LD	-4313.5	171.5
CD300LF	-4563.0	8233.0
CD300LG	7882.0	8461.0
CD33	-6278.5	7868.5
CD34	7928.0	8147.0
CD36	-7328.0	6006.0
CD3D	-3626.0	-15.0
CD3E	-1202.0	619.0
CD3G	-1784.0	-3919.0
CD4	409.0	5008.0
CD40	-1092.0	450.0
CD74	-4460.0	2932.0
CD79A	-4689.0	2648.0
CD79B	-2701.0	2433.0
CD80	-3453.0	3286.0
CD81	3188.0	6614.0
CD86	-2679.0	5554.0
CD8A	-3470.0	-1770.0
CD8B	-2337.5	645.5
CD96	-825.0	5826.0
CDC16	6701.0	3924.0
CDC20	6493.0	-3052.0
CDC23	1748.0	710.0
CDC26	-3331.0	1610.0
CDC27	-4452.0	8433.0
CDC34	-806.0	2346.0
CDC42	-5961.0	8129.0
CDH1	-1038.0	5837.0
CENPE	1973.0	460.0
CHUK	-3701.0	8556.0
CLEC2D	-5472.0	6761.0
CLTA	-2807.0	2774.0
CLTC	-4493.0	8248.0
COLEC12	190.0	8600.0
CRTAM	2374.0	41.0
CSK	-5802.0	-2193.0
CTSA	6070.0	1611.0
CTSB	7086.0	-1439.0
CTSC	-1974.0	7696.0
CTSD	5035.5	6716.5
CTSE	-1259.0	-4402.0
CTSF	7059.0	-4590.0
CTSH	-6661.0	6547.0
CTSK	-3257.0	7753.0
CTSO	1101.0	4475.0
CTSS	-5861.0	7572.0
CUL1	-2997.0	6875.0
CUL2	-6236.0	8506.0
CUL3	-3105.0	8488.0
CUL5	-5371.0	8605.0
CUL7	7850.0	-5060.0
CXADR	-7100.0	3254.0
CYBA	-4719.0	-4200.0
CYBB	-5520.0	5307.0
DAPP1	-2716.0	5499.0
DCTN1	7218.0	-3098.0
DCTN2	2623.0	-2017.0
DCTN3	-715.0	689.0
DCTN4	-4133.0	7527.0
DCTN5	-4033.0	5094.0
DCTN6	4374.0	7565.0
DET1	-2755.5	536.5
DNM1	7171.0	3067.0
DNM2	-1598.0	5364.0
DNM3	6014.0	942.0
DTX3L	-5714.0	592.0
DYNC1H1	4822.0	2594.0
DYNC1I1	3045.0	-5230.0
DYNC1I2	-251.0	7398.0
DYNC1LI1	2249.0	7292.0
DYNC1LI2	-1436.0	1861.0
DYNLL1	-6952.0	7645.0
DYNLL2	4932.0	-5028.0
DZIP3	-3939.0	-4126.0
ELOB	6643.0	3269.0
ELOC	-3325.0	7837.0
ENAH	5226.0	20.0
ERAP1	2696.0	2291.0
EVL	-186.0	264.0
FBXL12	6303.0	-6457.0
FBXL13	1597.0	-4376.0
FBXL14	3254.0	-5925.0
FBXL15	4607.0	-4358.0
FBXL16	4642.0	451.0
FBXL18	3324.0	-4163.0
FBXL19	-1608.0	-4038.0
FBXL20	3692.0	-5654.0
FBXL22	5538.0	-6092.0
FBXL3	-5113.0	5030.0
FBXL4	3694.0	2851.0
FBXL5	-5339.0	1379.0
FBXL7	-3047.0	1531.0
FBXL8	1855.5	-6099.5
FBXO10	-2534.0	-4069.0
FBXO11	-2703.0	8171.0
FBXO15	-1975.0	2890.0
FBXO17	3510.0	-1954.0
FBXO2	4620.0	4693.0
FBXO21	8209.0	-5962.0
FBXO22	-6695.0	4983.0
FBXO27	-2654.0	1841.0
FBXO30	-5216.0	5730.0
FBXO31	5477.0	-4217.0
FBXO32	7523.0	2250.0
FBXO4	-5534.0	5796.0
FBXO40	-4210.0	4616.0
FBXO6	7480.0	1442.0
FBXO7	-6524.0	-2660.0
FBXO9	-3297.0	-3812.0
FBXW10	-457.0	-3065.0
FBXW11	-3788.0	3125.0
FBXW12	858.0	-1111.0
FBXW2	2426.0	1249.0
FBXW4	6455.0	-3779.0
FBXW5	6633.0	-4037.0
FBXW7	-1739.0	4510.0
FBXW8	7356.0	-1698.0
FBXW9	7633.0	-5232.0
FCGR1A	-5675.5	4265.5
FCGR1B	-5675.5	4265.5
FCGR2B	-7297.0	5966.0
FCGR3A	-5407.5	6212.5
FKBP1A	-2857.5	-1534.5
FYN	-2200.0	6221.0
FZR1	3996.0	-5000.0
GAN	7738.0	-2732.0
GLMN	5282.0	4715.0
GRAP2	-2907.0	5211.0
GRB2	3285.0	1922.0
HACE1	1467.0	-3119.0
HCST	1372.0	-4295.0
HECTD1	5015.0	3615.0
HECTD2	4950.0	-5884.0
HECTD3	6360.0	-4972.0
HECW2	-2620.0	4695.0
HERC1	7079.0	-2274.0
HERC2	-123.0	-4460.0
HERC3	7944.5	-1993.5
HERC4	-7115.0	2915.0
HERC6	-4149.0	-4400.0
HLA-DMA	275.0	-5969.0
HLA-DMB	-1643.5	-3831.5
HLA-DOA	-5599.0	3997.0
HLA-DOB	-4577.0	-4767.0
HLA-DQB1	-4730.5	1217.5
HLA-DQB2	-4730.5	1217.5
HLA-DRB1	1762.5	-4711.5
HLA-DRB5	1762.5	-4711.5
HLA-E	3698.5	-6121.5
HLA-G	3698.5	-6121.5
HRAS	1503.0	-318.0
HSPA5	-7309.0	7589.0
HUWE1	-6141.0	3624.0
ICAM1	7342.0	7752.0
ICAM2	-3483.0	7311.0
ICAM4	997.0	2998.0
ICAM5	526.0	-1886.0
ICOS	-772.0	2670.0
ICOSLG	5675.5	2737.5
IFITM1	6414.0	8796.0
IGHM	5659.0	-3544.0
IGHV1-69	-7353.5	8845.5
IGHV2-5	4395.0	4965.0
IGHV2-70	4395.0	4965.0
IGHV7-81	517.5	7570.5
IGKC	-2925.0	7318.0
IGKV1-12	2052.5	4944.5
IGKV1-17	2052.5	4944.5
IGKV1-39	2052.5	4944.5
IGKV1D-12	2052.5	4944.5
IGKV1D-39	2052.5	4944.5
IGKV2-30	101.5	8396.5
IGKV2D-30	101.5	8396.5
IGKV4-1	-7301.0	8840.0
IGKV5-2	-5895.0	8671.0
IGLV4-60	-3537.5	3617.5
IGLV4-69	-3537.5	3617.5
IKBKB	-1785.0	-5829.0
IKBKG	3700.0	-677.0
INPP5D	-1230.0	5535.0
ITCH	-4378.0	5792.0
ITGA4	-6762.0	7.0
ITGAL	-4315.0	-1137.0
ITGAV	8155.0	2693.0
ITGB1	-6241.0	8758.0
ITGB2	-5238.0	412.0
ITGB5	7359.0	1316.0
ITGB7	-4595.0	346.0
ITK	-3536.0	2982.0
ITPR1	-2727.0	2512.0
ITPR2	4185.0	-2206.0
ITPR3	7844.0	5234.0
KBTBD13	2313.0	2189.0
KBTBD6	-6874.5	7477.5
KBTBD7	-6874.5	7477.5
KBTBD8	-2145.0	-505.0
KCTD6	5371.0	1842.0
KCTD7	3938.0	-338.0
KEAP1	-3703.0	-3144.0
KIF11	4262.0	-1098.0
KIF15	91.0	-5193.0
KIF18A	-2035.0	4687.0
KIF20A	3022.0	-1094.0
KIF22	-925.0	-1002.0
KIF23	6834.0	-2775.0
KIF26A	3470.0	3765.0
KIF2A	1251.0	7652.0
KIF2C	2591.0	-1946.0
KIF3A	-5126.0	3351.0
KIF3B	-3223.0	6725.0
KIF3C	-3455.0	5074.0
KIF4A	1014.0	6024.0
KIF5A	-5260.0	-5278.0
KIF5B	-1547.0	8819.0
KIF5C	6290.0	2117.0
KIFAP3	41.0	8075.0
KLC1	143.0	-5336.0
KLC2	6949.0	-4707.0
KLC3	7232.0	-1031.0
KLC4	-6395.0	-2860.0
KLHL11	4250.0	3553.0
KLHL13	-3686.0	6045.0
KLHL2	-6669.0	8214.0
KLHL20	-3947.0	1875.0
KLHL21	7522.0	-6646.0
KLHL22	-810.5	-5052.5
KLHL25	823.0	-4743.0
KLHL3	6109.0	2377.0
KLHL41	5118.0	-6151.0
KLHL42	-111.0	-2648.0
KLHL5	4270.0	3505.0
KLHL9	-5268.0	6137.0
KLRB1	6038.0	8197.0
KLRC1	-2897.5	4049.5
KLRD1	-3689.0	-3816.0
KLRK1	-5741.0	7328.0
KRAS	-752.0	8587.0
LAG3	-1925.0	-2900.0
LAIR1	-5670.0	-3164.0
LAT	1869.0	-481.0
LCK	-2194.0	5687.0
LCP2	-5980.0	1266.0
LGMN	7268.0	624.0
LILRA4	-7184.0	7732.0
LILRA5	-7184.0	7732.0
LILRA6	-7184.0	7732.0
LILRB3	-7184.0	7732.0
LILRB5	-7184.0	7732.0
LMO7	6730.0	-2505.0
LNPEP	4116.0	7467.0
LNX1	7569.0	3277.0
LONRF1	6353.0	-948.0
LRRC41	907.0	-3596.0
LRSAM1	4703.0	-4046.0
LTN1	-4333.0	7393.0
LY96	-4879.0	364.0
LYN	-4685.0	8216.0
MALT1	-2981.0	1806.0
MAP3K14	-4228.0	558.0
MAP3K7	1594.0	7480.0
MAP3K8	656.0	2671.0
MAPKAP1	-5825.0	6111.0
MEX3C	-1666.0	5740.0
MGRN1	7070.0	-883.0
MIB2	2255.0	-6580.0
MICA	-449.5	-3755.5
MICB	-449.5	-3755.5
MKRN1	-6560.0	3886.0
MLST8	-977.0	-1211.0
MRC1	-5573.0	7131.0
MRC2	1541.0	7216.0
MTOR	-4145.0	-2344.0
MYD88	-5933.0	3612.0
MYLIP	5136.0	-759.0
NCF1	3710.0	-659.0
NCF2	-1972.0	-3232.0
NCF4	-5987.0	5579.0
NCK1	-4610.0	8438.0
NCR1	-1842.0	-440.0
NECTIN2	8037.0	-2727.0
NEDD4	1235.0	7804.0
NEDD4L	1323.0	-3476.0
NFATC1	6099.0	7170.0
NFATC2	4913.0	-5797.0
NFATC3	-5299.0	6496.0
NFKB1	5449.0	4035.0
NFKBIA	1631.0	4830.0
NFKBIB	3850.0	467.0
NFKBIE	-4334.0	-123.0
NPDC1	-4485.0	-1226.0
NPEPPS	-4943.0	-1065.0
NRAS	3837.0	7903.0
ORAI1	5373.0	-3312.0
ORAI2	4113.0	4514.0
OSBPL1A	6468.0	6678.0
OSCAR	2024.0	-1438.0
PAG1	-2791.0	3849.0
PAK1	-886.0	5458.0
PAK2	-4906.0	6708.0
PAK3	2878.0	1881.0
PDCD1	-3283.0	5216.0
PDIA3	-7283.0	7821.0
PDPK1	-4074.0	1936.0
PIANP	-2775.0	-3811.0
PIK3AP1	-6075.0	3775.0
PIK3CA	-6347.0	2923.0
PIK3CB	-1756.0	1880.0
PIK3CD	-1968.0	1889.0
PIK3R1	-839.0	8363.0
PIK3R2	1669.5	-3969.5
PIK3R3	3779.5	8820.5
PJA1	-6100.0	4703.0
PJA2	1785.0	7657.0
PLCG1	8067.0	-4962.0
PLCG2	-5287.0	2474.0
PPIA	4868.0	-469.0
PPL	7566.0	183.0
PPP2CA	-5725.0	8237.0
PPP2CB	5588.0	159.0
PPP2R1A	6355.0	3115.0
PPP2R1B	-6463.0	4855.0
PPP2R5A	7319.0	1089.0
PPP2R5B	627.0	5414.0
PPP2R5C	3181.0	8384.0
PPP2R5D	2088.0	5911.0
PPP2R5E	5001.0	2898.0
PPP3CA	5123.0	6939.0
PPP3CB	-1150.0	4729.0
PPP3R1	2835.5	8199.5
PRKACA	-530.0	15.0
PRKACB	569.0	661.0
PRKCB	-5598.0	5660.0
PRKCQ	-2002.0	-3514.0
PRKG1	-2535.0	8589.0
PRR5	-6098.0	-5369.0
PSMA1	-6705.0	7838.0
PSMA2	-5464.5	6058.5
PSMA3	-3145.0	7801.0
PSMA4	-6074.0	4688.0
PSMA5	-6660.0	4497.0
PSMA6	-1954.0	8445.0
PSMA7	1612.0	7052.0
PSMA8	649.0	-4004.0
PSMB1	-5281.0	5936.0
PSMB10	3752.0	-908.0
PSMB11	1977.0	-5501.0
PSMB2	1472.0	-4144.0
PSMB3	-3388.0	5539.0
PSMB4	-4941.0	-5852.0
PSMB5	-1638.0	-2409.0
PSMB6	1806.0	-1845.0
PSMB7	-4628.0	-657.0
PSMB8	1080.0	-3793.0
PSMB9	5987.0	-4708.0
PSMC1	-1312.0	4327.0
PSMC2	-6765.0	4648.0
PSMC3	-4285.0	3386.0
PSMC4	-6423.0	7920.0
PSMC5	-4831.0	1120.0
PSMC6	-6851.0	8666.0
PSMD1	-6497.0	8619.0
PSMD10	-1613.0	2576.0
PSMD11	-6873.0	5201.0
PSMD12	-6149.0	8628.0
PSMD13	1898.0	5044.0
PSMD14	-6080.0	8262.0
PSMD2	-6702.0	-3836.0
PSMD3	-2532.0	-3242.0
PSMD4	-5648.0	4994.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
PSMD7	-6943.0	7625.0
PSMD8	1978.0	7546.0
PSMD9	7707.5	-894.5
PSME1	2907.0	5905.0
PSME2	1270.0	-4595.0
PSME3	752.0	7366.0
PSME4	-6830.0	8511.0
PSMF1	5087.0	4771.0
PTEN	-5726.0	8365.0
PTPN11	-3946.0	6142.0
PTPN22	-5957.0	3364.0
PTPN6	-1098.0	2140.0
PTPRC	-7112.0	6863.0
PTPRJ	3203.0	5737.0
PVR	-662.0	6696.0
RAB7A	-5898.0	8083.0
RAC1	-1258.0	4008.0
RACGAP1	6146.0	-2445.0
RAF1	-6377.0	2465.0
RAP1A	-6787.0	8805.0
RAP1B	942.0	8759.0
RAP1GAP	8071.0	-849.0
RAP1GAP2	7762.0	-1501.0
RAPGEF3	6998.0	-5986.0
RAPGEF4	-2613.0	5313.0
RASGRP1	-370.0	-2734.0
RASGRP2	-326.0	-409.0
RASGRP3	-6128.0	7243.0
RBBP6	3444.0	5157.0
RBCK1	3790.0	-3921.0
RBX1	-391.0	3201.0
RCHY1	-3461.0	4725.0
REL	-2309.0	7411.0
RELA	2579.0	-2368.0
RICTOR	493.0	4810.0
RILP	4974.0	-3084.0
RIPK2	5953.0	6306.0
RLIM	1169.0	7430.0
RNF111	-6255.0	5534.0
RNF114	-3572.0	338.0
RNF115	-528.0	6398.0
RNF123	3678.0	-5288.0
RNF126	5755.0	-4740.0
RNF130	-2655.0	5163.0
RNF138	-3827.0	7603.0
RNF14	-373.0	-1.0
RNF144B	7620.0	8253.0
RNF19A	3642.0	6667.0
RNF19B	-3119.0	-1959.0
RNF213	-6529.0	-265.0
RNF217	-1791.0	3219.0
RNF220	862.0	-1325.0
RNF25	-27.0	1761.0
RNF34	48.0	4672.0
RNF4	-981.0	6419.0
RNF41	474.0	2919.0
RNF6	-6183.0	1183.0
RNF7	-2546.0	5701.0
RPS27A	-133.0	-1807.0
SAR1B	-3423.0	7668.0
SEC13	-1432.0	3604.0
SEC22B	-4623.0	5601.0
SEC23A	-3552.0	8413.0
SEC24A	159.0	5121.0
SEC24B	-570.0	-3344.0
SEC24C	-5965.0	-1916.0
SEC24D	-6384.0	8428.0
SEC31A	835.0	-552.0
SEC61A1	-6475.0	-2203.0
SEC61A2	-3708.0	-6590.0
SEC61B	-6411.0	-260.0
SEC61G	-2855.0	8720.0
SELL	-4022.0	902.0
SH2D1B	-4335.0	-295.0
SH3GL2	-6503.0	867.0
SH3KBP1	3805.0	5866.0
SH3RF1	431.0	-2692.0
SIAH1	4474.0	5949.0
SIAH2	1504.0	-2759.0
SIGLEC1	1121.0	-6191.0
SIGLEC10	-4900.5	1627.5
SIGLEC11	-4900.5	1627.5
SIGLEC12	-2039.5	-2039.5
SIGLEC6	-6278.5	7868.5
SIGLEC7	-2039.5	-2039.5
SIGLEC8	-2039.5	-2039.5
SIGLEC9	-2039.5	-2039.5
SIPA1	-3901.0	3867.0
SKP1	-6803.0	8394.0
SKP2	5738.0	-4232.0
SLAMF6	-693.0	-2721.0
SLAMF7	-4972.0	4007.0
SMURF1	7065.0	-1671.0
SMURF2	-6772.0	5752.0
SNAP23	-6477.0	8059.0
SOCS1	-253.0	-5520.0
SOCS3	4231.0	7185.0
SOS1	-6566.0	7698.0
SPSB1	7434.0	4252.0
SPSB2	-6665.0	-4813.0
SPSB4	-5638.0	-1459.0
SPTBN2	7922.0	-2952.0
SRC	-2657.0	-1643.0
STIM1	7832.0	6223.0
STUB1	4177.0	-2823.0
STX4	-3184.0	-4491.0
SYK	-6921.0	4480.0
TAB2	-7040.0	7307.0
TAP1	5427.0	-6060.0
TAP2	5211.5	-5555.5
TAPBP	6125.0	-2067.0
THEM4	-3393.0	6155.0
THOP1	5354.0	-4286.0
TIRAP	-3143.0	6369.0
TLR1	-3224.0	560.0
TLR2	5407.0	5188.0
TLR4	-4128.0	8470.0
TLR6	-4778.0	7142.0
TNFRSF14	872.0	-1648.0
TPP2	-4861.0	7558.0
TRAF6	1082.0	6626.0
TRAF7	1593.0	1363.0
TRAIP	3739.0	2143.0
TRAT1	-2279.0	-5760.0
TRBC1	-2602.5	6825.5
TREM1	169.0	-2242.0
TREM2	-4021.0	2867.0
TREML2	-3185.0	3037.0
TREML4	1759.0	-1379.0
TRIB3	3661.0	-614.0
TRIM11	5691.0	-6686.0
TRIM21	344.0	-452.0
TRIM32	-6017.0	-3715.0
TRIM36	5392.0	1747.0
TRIM37	-6310.0	-2309.0
TRIM39	-3968.0	-5404.0
TRIM41	7182.0	-6307.0
TRIM63	-2296.0	2181.0
TRIM71	2231.0	-2446.0
TRIM9	210.0	2035.0
TRIP12	-6590.0	8167.0
TRPC1	-5396.0	1920.0
TYROBP	-4245.0	2276.0
UBA1	-3069.0	6814.0
UBA3	-3218.0	8194.0
UBA5	-6506.0	1620.0
UBA52	7488.0	-4269.0
UBA6	-6905.0	6312.0
UBA7	-3088.0	-3909.0
UBAC1	6069.0	-2026.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
UBE2A	-4551.0	7336.0
UBE2B	-4389.0	7152.0
UBE2C	733.0	-1864.0
UBE2D1	5638.0	3025.0
UBE2D2	-935.0	6690.0
UBE2D3	-5084.0	8317.0
UBE2E1	-6831.0	8405.0
UBE2E2	2753.0	4580.0
UBE2E3	441.0	4538.0
UBE2F	-4113.5	4926.5
UBE2G1	6022.0	6179.0
UBE2G2	-6897.0	3570.0
UBE2H	-2417.0	3799.0
UBE2J1	-4894.0	8195.0
UBE2J2	-1329.0	4541.0
UBE2K	-3148.0	7485.0
UBE2L3	-4226.5	5465.5
UBE2L6	809.0	5322.0
UBE2M	3424.0	2257.0
UBE2O	5265.0	-1823.0
UBE2Q1	4503.0	-393.0
UBE2Q2	-701.0	7516.0
UBE2R2	-4372.0	2763.0
UBE2S	4549.0	-1742.0
UBE2U	1482.0	8032.0
UBE2V2	-4079.0	8295.0
UBE2W	-2829.5	4199.5
UBE2Z	1411.0	812.0
UBE3A	-1965.0	8537.0
UBE3B	7311.0	-3273.0
UBE3C	-674.0	2056.0
UBE3D	1867.0	-59.0
UBE4A	-6479.0	2398.0
UBOX5	2216.0	-72.0
UBR1	5243.0	6623.0
UBR2	-6912.0	-5650.0
UBR4	4082.0	-4874.0
UFL1	-1900.0	7520.0
ULBP1	-5737.0	-420.0
ULBP3	-5737.0	-420.0
UNKL	-7141.0	2538.0
VAMP3	1693.0	5955.0
VAMP8	-3005.0	5301.0
VASP	-2568.0	4503.0
VAV1	-4395.0	5076.0
VCAM1	-4983.0	4280.0
WAS	-11.0	299.0
WSB1	7892.0	1113.0
WWP1	-6879.0	6537.0
XDH	8158.0	1436.0
YES1	-120.0	7265.0
YWHAB	-4723.0	8579.0
YWHAZ	-5614.0	8512.0
ZAP70	4159.0	1153.0
ZBTB16	2742.0	1122.0
ZNRF1	625.0	-4092.0
ZNRF2	-7152.0	5062.0

---

---

Disease

Disease

metric	value
setSize	1333
pMANOVA	8.84e-17
p.adjustMANOVA	1.38e-14
s.dist	0.143
s.diabetes	-0.0217
s.mitoG	0.142
p.diabetes	0.189
p.mitoG	9.26e-18

Top 20 genes

Gene	diabetes	mitoG
IGHV1-69	-7353.5	8845.5
IGKV4-1	-7301.0	8840.0
HSP90AA1	-7286.0	8742.0
PTGES3	-7067.0	8733.0
RAP1A	-6787.0	8805.0
PSMC6	-6851.0	8666.0
UBB	-7104.0	8341.0
CANX	-6936.0	8532.0
KPNA4	-6802.0	8691.0
DNAJC3	-7149.0	8179.0
PSME4	-6830.0	8511.0
UBE2E1	-6831.0	8405.0
SKP1	-6803.0	8394.0
PSMD1	-6497.0	8619.0
C1GALT1C1	-6956.0	8035.0
PRDX1	-6422.0	8698.0
SEL1L	-7264.0	7670.0
FGFR1OP2	-6599.0	8434.0
HDAC2	-6396.0	8620.0
ITGB1	-6241.0	8758.0

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
AAAS	5561.0	-2261.0
ABCA1	4025.0	-5420.0
ABCA12	1828.0	-2183.0
ABCA3	1074.0	-4546.0
ABCA4	277.0	-4736.0
ABCB4	2164.0	-5686.0
ABCB6	1084.0	-6083.0
ABCC2	8240.0	5236.0
ABCC6	6019.0	-6760.0
ABCC9	-2411.0	1507.0
ABCD1	3997.0	-5967.0
ABCD4	8139.0	-5758.0
ABCG8	4044.0	-2963.0
ABI1	-4630.0	8305.0
ABI2	4154.0	8369.0
ABL1	5557.0	-3567.0
ACACA	-6585.0	2967.0
ACE2	8047.0	1319.0
ACTB	-4152.0	7953.0
ACTG1	-1502.0	1482.0
ACTR2	-5189.0	7356.0
ACTR3	-3716.0	8206.0
ACY1	-1207.5	-4016.5
ADAM10	-6444.0	8149.0
ADAM17	-5121.0	3275.0
ADAMTS1	-5452.0	8739.0
ADAMTS10	4075.0	-5365.0
ADAMTS12	3513.0	5824.0
ADAMTS13	676.0	3925.0
ADAMTS14	3645.0	-1429.0
ADAMTS15	-1865.0	-5976.0
ADAMTS16	6061.0	-5109.0
ADAMTS17	898.0	-2086.0
ADAMTS18	5565.0	-5223.0
ADAMTS19	-1084.0	3439.0
ADAMTS2	-2074.0	8088.0
ADAMTS3	5455.0	1208.0
ADAMTS4	-4558.0	7178.0
ADAMTS5	4732.0	6838.0
ADAMTS6	3714.0	2516.0
ADAMTS7	-3098.0	6102.0
ADAMTS8	3341.0	380.0
ADAMTS9	-4215.0	5871.0
ADAMTSL1	7394.0	7561.0
ADAMTSL2	1075.0	7367.0
ADAMTSL3	8145.0	-5509.0
ADAMTSL4	4218.0	4581.0
ADAMTSL5	4696.0	588.0
ADCY1	-4196.0	1876.0
ADCY2	5891.0	1358.0
ADCY3	-351.0	4656.0
ADCY4	-237.0	7618.0
ADCY5	2277.0	2395.0
ADCY6	7278.0	-6203.0
ADCY7	-5272.0	-2210.0
ADCY8	3778.0	-3880.0
ADCY9	2137.0	-5459.0
ADCYAP1	-2784.0	6784.0
ADCYAP1R1	6820.0	4772.0
ADM	7469.0	6606.0
ADM2	-2536.0	-3876.0
ADORA2A	-2349.0	1070.0
ADORA2B	-2957.0	819.0
ADRB1	5207.0	-4492.0
ADRB2	-6910.0	4340.0
AGGF1	-5856.5	4390.5
AGK	2444.0	4916.0
AGRN	-2966.0	-6131.0
AGTRAP	-4487.0	-6054.0
AHCY	-3362.0	-6342.0
AHCYL1	-5585.0	5114.0
AKAP9	-4986.0	7264.0
AKT1	4859.0	7244.0
AKT1S1	3062.0	-5699.0
AKT2	-4939.0	3281.0
AKT3	-375.0	7862.0
ALDOB	6728.0	7388.0
ALG1	-2121.0	-4072.0
ALG11	-1679.0	4323.0
ALG12	-3609.0	1483.0
ALG14	-5434.0	4618.0
ALG2	-6555.0	5827.0
ALG3	-509.0	-3892.0
ALG6	706.0	-1870.0
ALG8	-6352.0	1201.0
ALG9	-2677.5	-938.5
AMER1	1557.0	4171.0
AMN	-3075.0	-6644.0
ANAPC1	-6298.0	2903.0
ANAPC10	-1783.0	4951.0
ANAPC15	4299.0	155.0
ANAPC16	2.0	1444.0
ANAPC2	-3336.0	-4659.0
ANAPC4	6315.0	5808.0
ANAPC5	6285.0	-1473.0
ANAPC7	5249.0	-3454.0
ANTXR1	7856.0	7620.0
ANTXR2	1970.0	5230.0
AP1B1	5867.0	-3224.0
AP1G1	-6928.0	3255.0
AP1M1	2796.0	-3928.0
AP1M2	7170.0	-121.0
AP1S1	-667.0	-1428.0
AP1S2	-2308.0	7787.0
AP1S3	483.0	-6543.0
AP2A1	3192.0	-2941.0
AP2A2	-6231.0	249.0
AP2B1	-3990.0	7426.0
AP2M1	5073.0	2926.0
AP2S1	587.0	7094.0
AP3B1	3159.0	1998.0
APBB1IP	-5251.0	-2322.0
APC	4716.0	8376.0
APH1A	5635.0	-6359.0
APH1B	7972.0	373.0
APOA1	3682.0	-305.0
APP	-5115.0	6758.0
ARAF	4130.0	-5879.0
ARF1	-5273.0	7470.0
ARID4A	-4003.0	6886.0
ARID4B	1679.0	5415.0
ARPC1A	-1009.0	-3070.0
ARPC1B	7126.0	2266.0
ARPC2	-4512.0	8767.0
ARPC3	-5747.0	8757.0
ARPC4	3077.0	1525.0
ARPC5	920.0	7514.0
ARRB1	-6250.0	3030.0
ARRB2	-3644.0	681.0
ARSB	-5231.0	2994.0
ATG7	7859.0	-906.0
ATP1A1	8085.0	4179.0
ATP1A2	1265.0	3781.0
ATP1A3	-3332.5	4126.5
ATP1B1	8146.0	7502.0
ATP1B2	-1075.0	6478.0
ATP1B3	-1025.0	8436.0
ATP6V1H	-1095.0	8501.0
AVPR1A	-6547.0	2421.0
AVPR1B	1354.0	-5458.0
AVPR2	4980.0	2853.0
AXIN1	2211.0	-3480.0
B2M	5339.0	4978.0
B3GALT6	-4238.0	3876.0
B3GAT3	-4118.0	-2576.0
B3GLCT	2664.0	5363.0
B4GALT1	-356.0	-3621.0
B4GALT7	1147.0	-2488.0
B4GAT1	7224.0	-6185.0
BAD	-2216.0	-4664.0
BAG4	7654.0	5147.0
BAIAP2	7911.0	534.0
BANF1	3561.0	-458.0
BCAN	1188.0	-1033.0
BCL2L11	7084.0	668.0
BCR	-1554.0	-5381.0
BDNF	3549.0	125.0
BGN	6078.0	8647.0
BIN2	-3519.0	1037.0
BRAF	-6284.0	4955.0
BRAP	-3859.0	735.0
BRD4	-4805.0	1284.0
BRK1	751.0	1659.0
BRMS1	1673.0	7971.0
BSG	-3166.0	5032.0
BTC	7701.0	1951.0
BTD	-3970.0	1048.0
BTK	-5279.0	5486.0
BTRC	3218.0	-5334.0
C1GALT1	-6844.0	7463.0
C1GALT1C1	-6956.0	8035.0
C1QBP	4206.0	1754.0
C3	7675.0	3404.0
C3AR1	-1253.0	7488.0
CALCA	-3485.0	-2743.0
CALCR	-2793.0	1335.0
CALCRL	-3264.0	8776.0
CALM1	-4401.0	8702.0
CALR	-7105.0	5809.0
CAMK2A	-2272.0	4664.0
CAMK2B	2551.0	5253.0
CAMK2G	5581.0	-3540.0
CAMK4	-481.0	-1872.0
CANX	-6936.0	8532.0
CAPN1	7308.0	-2267.0
CAPN2	5357.0	7435.0
CAPNS1	1113.0	6245.0
CASP1	-1051.0	1558.0
CASP8	-5258.0	8694.0
CASP9	2469.0	-5751.0
CAST	3920.0	8492.0
CBL	-6462.0	4306.0
CBLL1	175.0	4700.0
CCNC	-3288.0	7605.0
CCND1	7933.0	-1628.0
CCND2	-6019.5	7675.5
CCND3	6126.0	-3725.0
CCNE1	5096.0	360.0
CCNE2	2080.0	3324.0
CCNH	-5547.0	6108.0
CCNK	1018.0	3257.0
CCNT1	-709.0	6941.0
CCNT2	-1826.0	951.0
CCR5	-1106.0	281.0
CD14	4081.0	6994.0
CD163	-2470.0	7418.0
CD19	-2666.0	-3652.0
CD247	1213.0	-5666.0
CD28	-4408.0	5134.0
CD320	3164.0	-4419.0
CD36	-7328.0	6006.0
CD3G	-1784.0	-3919.0
CD4	409.0	5008.0
CD80	-3453.0	3286.0
CD86	-2679.0	5554.0
CD8B	-2337.5	645.5
CD9	7375.0	4550.0
CDC16	6701.0	3924.0
CDC23	1748.0	710.0
CDC25A	-5099.0	1807.0
CDC25B	7078.0	-3033.0
CDC25C	2845.0	-538.0
CDC26	-3331.0	1610.0
CDC27	-4452.0	8433.0
CDC37	-682.0	-4414.0
CDC42	-5961.0	8129.0
CDH1	-1038.0	5837.0
CDK2	6186.0	-4240.0
CDK4	3355.0	-1971.0
CDK5	2069.0	-2606.0
CDK5R1	4903.0	-6336.0
CDK6	-5570.0	908.0
CDK7	-258.0	3661.0
CDK8	5984.0	-5196.0
CDK9	315.0	-5322.0
CDKN1A	7594.0	6372.0
CDKN1B	541.0	3790.0
CDKN1C	8161.0	5620.0
CEBPD	3288.0	6984.0
CEP43	1089.0	2218.0
CFP	-3458.0	-5006.0
CFTR	-6902.0	4865.0
CHD3	-7230.0	-2465.0
CHD4	5349.5	5970.5
CHMP1A	2980.0	-5932.0
CHMP2A	3891.0	6246.0
CHMP2B	-3672.0	8606.0
CHMP3	-5181.5	8584.5
CHMP4B	7103.0	2636.0
CHMP4C	6678.0	1533.0
CHMP5	-4004.0	8542.0
CHMP6	4209.0	-2043.0
CHMP7	-57.0	-2549.0
CHST14	5900.0	-4857.0
CHST3	-96.0	2845.0
CHSY1	-1431.0	5798.0
CHUK	-3701.0	8556.0
CLCN6	-5634.0	-5403.0
CLTA	-2807.0	2774.0
CLTC	-4493.0	8248.0
CNKSR1	7454.0	1081.0
CNKSR2	3628.0	-207.0
CNTRL	6882.0	1622.0
COMT	-7046.0	5137.0
CORO1A	-3183.0	-17.0
CP	7736.0	7894.0
CPSF4	-267.0	514.0
CPSF6	-4618.0	2233.0
CRBN	2027.0	6641.0
CREB1	-6809.0	5166.0
CREBBP	-6181.0	3954.0
CRHR2	-903.0	2018.0
CRK	-3124.0	6926.0
CSF2RA	-2892.0	-5044.0
CSF2RB	-5554.0	-817.0
CSK	-5802.0	-2193.0
CSNK1A1	3705.0	5154.0
CSPG4	8154.0	-6277.0
CSPG5	-1773.0	-788.0
CTBP1	2741.0	-5332.0
CTBP2	7553.0	1467.0
CTDP1	6939.0	2918.0
CTNNB1	-6022.0	2664.0
CTNND1	5833.0	1565.0
CTSA	6070.0	1611.0
CUBN	5596.0	263.0
CUL1	-2997.0	6875.0
CUL5	-5371.0	8605.0
CUX1	-7126.0	4438.0
CXCR4	4516.0	7547.0
CYBA	-4719.0	-4200.0
CYFIP1	3175.0	7476.0
CYFIP2	7791.0	-143.0
CYP11A1	-1866.0	5478.0
CYP17A1	5201.0	-486.0
CYP1B1	7373.0	8462.0
CYP24A1	5963.0	4072.0
CYP26B1	-3693.0	4378.0
CYP26C1	602.0	-5399.0
CYP27A1	7503.0	3659.0
CYP27B1	4131.0	-2865.0
CYP2R1	-4480.0	2939.0
CYP2U1	4939.0	30.0
CYP7B1	-5009.0	2252.0
CYSLTR1	-4800.0	4502.0
DAD1	-601.0	-4283.0
DAG1	6646.0	3480.0
DAXX	-867.0	1599.0
DBP	8002.0	-5295.0
DCN	3643.0	8458.0
DCXR	5278.0	-4512.0
DDOST	-5017.0	2674.0
DDX5	-3313.0	-2478.0
DERL1	-5101.0	3639.0
DERL2	-7153.0	6854.0
DERL3	-4530.0	-5374.0
DHDDS	-4632.0	-1973.0
DHH	-575.0	3243.0
DKK1	2430.0	-4371.0
DKK2	-5122.0	8325.0
DKK4	-3253.0	2039.0
DLL1	-4076.0	-1816.0
DLL4	-3454.0	4023.0
DNAJC3	-7149.0	8179.0
DOCK1	2243.0	382.0
DOCK2	-5657.0	5085.0
DOLK	-1597.0	-6134.0
DPAGT1	-4124.0	-3201.0
DPEP1	1301.0	5412.0
DPEP2	3373.0	1639.0
DPM1	4121.0	435.0
DPM2	4055.0	2348.0
DPM3	-20.0	-5789.0
DRD1	-1465.0	4255.0
DUSP10	4557.0	5745.0
DUSP16	-3468.0	8092.0
DUSP6	-5078.0	6412.0
DUSP7	7818.0	-3862.0
DUSP8	4090.0	3420.0
DUSP9	5294.0	-3689.0
DUT	1159.0	688.0
DVL1	6741.0	-6179.0
DVL2	7754.0	-6212.0
DVL3	7325.0	-4734.0
DYNC1H1	4822.0	2594.0
DYNC1I1	3045.0	-5230.0
DYNC1I2	-251.0	7398.0
DYNC1LI1	2249.0	7292.0
DYNC1LI2	-1436.0	1861.0
DYNLL1	-6952.0	7645.0
DYNLL2	4932.0	-5028.0
E2F1	4935.0	-488.0
E2F2	-2674.0	6447.0
E2F3	-3234.0	5297.0
EDEM2	-3522.0	-3508.0
EED	-1977.0	6430.0
EEF2	-3312.0	2063.0
EGF	-4765.0	-210.0
EGFR	-6023.0	1902.0
EIF2AK2	4174.0	5292.0
ELK1	3201.0	-1060.0
ELL	6782.0	805.0
ELMO1	-4833.0	4917.0
ELMO2	6218.0	-536.0
ELOA	7447.0	7874.0
ELOB	6643.0	3269.0
ELOC	-3325.0	7837.0
ENO1	8244.0	7737.0
ENTPD1	6740.0	7163.0
ENTPD5	6385.0	3766.0
EP300	-2449.0	1336.0
EPM2A	6139.0	-2279.0
EPS15	-5197.0	5904.0
ERBB2	6521.0	-6707.0
ERBB3	3712.0	-75.0
ERBB4	2718.0	2425.0
ERBIN	-100.0	7851.0
ERCC2	6295.0	-6411.0
ERCC3	-2263.0	1771.0
ERLEC1	-3854.0	8504.0
ERLIN1	-7147.0	4833.0
ERLIN2	-5110.0	-648.0
ESR1	-187.0	-1356.0
ESR2	2298.0	-2563.0
ESRP1	7191.0	2251.0
ETV6	-2325.0	2640.0
EXT1	-1529.0	4370.0
EXT2	3219.0	2652.0
EZH2	13.0	1789.0
F10	7628.0	-1082.0
F2	-3087.0	4699.0
F8	-688.0	7499.0
FADD	6301.0	-5424.0
FAM114A2	-4892.0	3284.0
FASLG	834.0	4880.0
FAU	6809.0	7710.0
FBXW7	-1739.0	4510.0
FCGR1A	-5675.5	4265.5
FCGR2A	-7297.0	5966.0
FCGR3A	-5407.5	6212.5
FDX1	-3799.0	389.0
FDX2	-5934.5	5631.5
FEN1	-277.0	298.0
FGA	4508.0	5893.0
FGB	3640.0	3338.0
FGF1	-6961.0	3296.0
FGF10	-2375.0	-1761.0
FGF16	3777.0	-2317.0
FGF18	5790.0	-4625.0
FGF2	792.0	3696.0
FGF22	7063.0	-4758.0
FGF9	2653.0	-2366.0
FGFR1	6753.0	-812.0
FGFR1OP2	-6599.0	8434.0
FGFR2	6750.0	6454.0
FGFR3	7673.0	-6608.0
FGFR4	-4841.0	-4690.0
FGG	5980.0	5427.0
FGR	-3144.0	378.0
FKBP1A	-2857.5	-1534.5
FKBP4	-7096.0	-111.0
FMO3	3331.0	5124.0
FMOD	6304.0	4032.0
FN1	7489.0	8379.0
FOXO1	6562.0	90.0
FOXO3	7446.0	393.0
FOXO4	257.0	-4431.0
FOXO6	-2112.0	3156.0
FRS2	-3456.0	5571.0
FURIN	3696.0	-3590.0
FUT8	-5026.0	4575.0
FXR1	-4671.0	5684.0
FXYD1	-583.0	7074.0
FXYD2	-3344.5	4429.5
FXYD4	1149.0	10.0
FXYD6	412.0	7190.0
FYN	-2200.0	6221.0
FZD4	6121.0	5562.0
FZD5	2921.0	2259.0
FZD6	4610.0	5434.0
FZD7	4413.0	-2110.0
FZD8	-293.0	-3285.0
FZR1	3996.0	-5000.0
G6PC	-4387.0	3036.0
G6PC3	-77.0	-5754.0
GAA	-3821.0	-2398.0
GAB1	-4598.0	-3742.0
GAB2	-717.0	7438.0
GALE	-148.0	-1536.0
GALK1	5722.0	-6298.0
GALNS	-6518.0	51.0
GALNT1	-6827.0	6806.0
GALNT12	6172.0	-2979.0
GALNT3	-6728.0	6831.0
GALT	7317.0	-476.0
GANAB	-6749.0	-2365.0
GATAD2A	-190.0	5669.0
GATAD2B	-2967.0	5239.0
GBE1	-1656.0	8320.0
GCLC	3508.0	7117.0
GCLM	-6988.0	3072.0
GFPT1	-5236.0	4132.0
GGCX	-6750.0	-4579.0
GGT1	-7165.0	-1432.0
GGT5	1563.0	6027.0
GHRHR	3635.0	3159.0
GLB1	-5376.0	2645.0
GLP1R	-3107.0	1309.0
GNAI1	-6368.0	8547.0
GNAI2	6737.0	5825.0
GNAI3	-3916.0	8277.0
GNAS	-2825.0	5946.0
GNAZ	-1947.0	4122.0
GNB1	1685.0	7974.0
GNB2	5389.0	-1847.0
GNB4	-4648.0	2711.0
GNB5	4543.0	3032.0
GNE	5717.0	4001.0
GNG10	5845.0	2921.0
GNG11	-2960.0	5884.0
GNG12	-1212.0	6898.0
GNG2	4011.0	7569.0
GNG3	-1825.0	1443.0
GNG4	-653.0	-591.0
GNG5	-2879.0	-1254.0
GNG7	1904.0	-4062.0
GNG8	499.0	-762.0
GNGT1	1972.0	5695.0
GNGT2	-1053.0	5102.0
GNS	8072.0	1691.0
GOLGA4	-3479.0	-714.0
GP1BA	7155.0	-6272.0
GP5	578.0	-4171.0
GP9	-4397.0	3026.0
GPC1	7890.0	581.0
GPC2	-2976.0	-1110.0
GPC3	-3602.0	6611.0
GPC4	-6484.0	-3662.0
GPC5	-4977.0	-3337.0
GPC6	-257.0	7981.0
GPR176	-1437.0	7990.0
GPR20	-684.0	-2071.0
GPR27	-995.0	4679.0
GPR39	1163.0	-286.0
GPS2	1228.0	2826.0
GRB2	3285.0	1922.0
GRSF1	4054.0	-1610.0
GSK3A	3838.0	1447.0
GSK3B	-5423.0	7184.0
GSS	-4718.0	305.0
GTF2A1	-940.0	5933.0
GTF2A2	505.0	6107.0
GTF2B	-1890.0	6217.0
GTF2E1	-2217.0	6482.0
GTF2E2	-2968.0	2878.0
GTF2F1	373.0	6337.0
GTF2F2	-1458.0	7912.0
GTF2H1	-6106.0	8498.0
GTF2H2	-3368.5	7043.5
GTF2H3	-1824.0	-2008.0
GTF2H4	3818.0	-4105.0
GTF2H5	1998.0	783.0
GUSB	-7203.0	1338.0
GYG1	27.0	6415.0
GYS1	8121.0	-4022.0
GYS2	-6113.0	3883.0
H2AC20	7413.0	2470.0
H2AC21	6478.0	633.0
H2AW	-5259.0	4003.0
H2BC11	3900.0	-3127.0
H2BC14	1703.0	1613.0
H2BC18	4839.0	6098.0
H2BC5	3445.0	-761.0
H3C15	7988.0	2080.0
HBEGF	-6694.0	-80.0
HCK	-3484.0	-1326.0
HDAC1	-3050.0	4701.0
HDAC10	6185.0	-5298.0
HDAC11	6709.0	-5647.0
HDAC2	-6396.0	8620.0
HDAC3	5142.0	-772.0
HDAC4	3270.0	-868.0
HDAC5	3656.0	-6773.0
HDAC6	7878.0	1757.0
HDAC7	5870.0	-2839.0
HDAC8	3387.5	-6320.5
HDAC9	93.0	1799.0
HEPH	-3944.0	6444.0
HES1	7353.0	4261.0
HEXA	6254.5	2667.5
HEXB	-6611.0	-740.0
HEY1	-484.0	3446.0
HEY2	-4053.0	4359.0
HEYL	-5342.0	-664.0
HGF	-6226.0	7929.0
HGS	-1920.0	704.0
HGSNAT	6373.0	2744.0
HHAT	7329.0	-2837.0
HK1	7506.0	4598.0
HLCS	5973.0	-4716.0
HMG20B	6566.0	-1264.0
HMGA1	7803.0	-1488.0
HNRNPK	-808.0	7246.0
HRAS	1503.0	-318.0
HRH2	-2405.0	714.0
HSP90AA1	-7286.0	8742.0
HSP90AB1	-7306.0	5626.0
HSPA1A	-7272.5	7293.5
HSPG2	5843.0	5956.0
HYAL1	5242.0	3316.0
ICOS	-772.0	2670.0
IDH1	5264.0	7348.0
IDS	-4361.5	6034.5
IDUA	4110.0	3194.0
IFNAR1	-1479.0	4534.0
IFNAR2	-850.5	5706.5
IFNGR1	-4655.0	6148.0
IFNGR2	4633.0	5019.0
IGHV1-69	-7353.5	8845.5
IGHV2-5	4395.0	4965.0
IGHV2-70	4395.0	4965.0
IGHV7-81	517.5	7570.5
IGKC	-2925.0	7318.0
IGKV1-12	2052.5	4944.5
IGKV1-17	2052.5	4944.5
IGKV1-39	2052.5	4944.5
IGKV1D-12	2052.5	4944.5
IGKV1D-39	2052.5	4944.5
IGKV2-30	101.5	8396.5
IGKV2D-30	101.5	8396.5
IGKV4-1	-7301.0	8840.0
IGKV5-2	-5895.0	8671.0
IGLV4-60	-3537.5	3617.5
IGLV4-69	-3537.5	3617.5
IHH	6365.0	-5234.0
IKBKB	-1785.0	-5829.0
IKBKG	3700.0	-677.0
IL18	4167.0	-3592.0
IL1A	-1142.0	1688.0
IL1B	-6242.0	3978.0
IL1R1	3443.0	7288.0
IL6R	-730.0	6215.0
IMPDH1	1190.0	4821.0
IMPDH2	4946.0	4658.0
IPO5	7411.0	3285.0
IQGAP1	7427.0	8123.0
IRAK4	2339.0	4636.0
IRS1	7064.0	-5549.0
IRS2	-582.0	3045.0
ISG15	-1124.0	-2998.0
ITGA2B	4961.0	-4170.0
ITGA4	-6762.0	7.0
ITGB1	-6241.0	8758.0
ITGB3	1530.5	4298.5
ITPR1	-2727.0	2512.0
ITPR2	4185.0	-2206.0
ITPR3	7844.0	5234.0
JAG1	-5328.0	3609.0
JAG2	-2757.0	2836.0
JAK1	-6481.0	8390.0
JAK2	-2268.0	5565.0
JAK3	7556.0	-6301.0
JUN	581.0	5314.0
KANK1	-2615.0	-1388.0
KAT2A	-3442.0	-2675.0
KAT2B	-5780.0	6796.0
KCNJ11	2961.0	-3265.0
KDM1A	5314.0	-44.0
KDM7A	5452.0	5988.0
KDR	-4380.0	8170.0
KHK	-1811.0	2087.0
KIAA1549	2144.0	-3229.0
KIT	-1277.0	3432.0
KITLG	-4636.0	7908.0
KL	-5761.0	-554.0
KLKB1	1003.0	5833.0
KPNA1	-5632.0	8815.0
KPNA2	2229.0	5432.0
KPNA3	-1498.0	8389.0
KPNA4	-6802.0	8691.0
KPNB1	-1668.0	5829.0
KRAS	-752.0	8587.0
KREMEN1	4699.0	400.0
KREMEN2	-1162.0	-4289.0
KSR1	-476.0	6166.0
KSR2	-7260.0	-2161.0
LARGE1	1668.0	1564.0
LCK	-2194.0	5687.0
LCT	-1231.0	-2471.0
LFNG	7713.0	3016.0
LHCGR	-5643.5	-1575.5
LIG1	4884.0	892.0
LIG4	-3349.0	7573.0
LMBRD1	4227.0	4468.0
LMNA	5092.0	-3667.0
LMNB1	6899.0	-4624.0
LRAT	-1726.0	2615.0
LRP5	7865.0	548.0
LRP6	1338.0	1716.0
LRRFIP1	5342.0	6570.0
LTF	-2111.0	1638.0
LUM	4367.0	7749.0
LY96	-4879.0	364.0
LYN	-4685.0	8216.0
MAGT1	-6822.0	7703.0
MAML1	4934.0	2236.0
MAML2	7613.0	4513.0
MAML3	7180.0	5765.0
MAMLD1	6705.0	2789.0
MAN1B1	-1873.0	-6055.0
MAN2A1	8162.0	5453.0
MAOA	3741.0	-492.0
MAP1LC3B	3858.5	3812.5
MAP2K1	7852.0	3274.0
MAP2K2	-2882.5	-4769.5
MAP2K3	3494.0	-249.0
MAP2K4	2621.0	5572.0
MAP2K6	5640.0	-4115.0
MAP2K7	3505.0	-3383.0
MAP3K11	-195.0	-4556.0
MAPK1	-3928.0	6920.0
MAPK14	-6337.0	-1012.0
MAPK3	5390.0	5167.0
MAPK8	-3252.0	1695.0
MAPKAP1	-5825.0	6111.0
MARK3	-6565.0	6767.0
MBD3	-3411.0	-3558.0
MC1R	583.0	7055.0
MC2R	2425.0	5288.0
MC3R	-1127.0	-884.0
MCCC1	-5695.0	1708.0
MCCC2	-3022.0	-403.0
MDM2	5569.0	7967.0
MECP2	7588.0	-950.0
MEFV	-4277.0	5186.0
MET	-7325.0	3597.0
MGAT1	-2205.0	-4578.0
MGAT2	-4100.0	4842.0
MGAT4A	8028.0	2426.0
MGAT4B	6084.0	-4137.0
MGAT4C	6273.0	-4542.0
MGAT5	-6087.0	2955.0
MIB1	-2528.0	4160.0
MIB2	2255.0	-6580.0
MLH1	5288.0	-5779.0
MLST8	-977.0	-1211.0
MMAA	-6584.0	4238.0
MMAB	6161.0	-4519.0
MMACHC	1165.0	5604.0
MMADHC	-5372.0	6261.0
MMUT	-4754.0	5281.0
MNAT1	1928.0	4358.0
MOGS	-7081.0	-6077.0
MPDU1	3608.0	-2985.0
MPI	-1157.0	6001.0
MPRIP	-2232.0	5169.0
MRAS	6507.0	4369.0
MRC1	-5573.0	7131.0
MSH2	7784.0	-3657.0
MSH3	1132.0	-2806.0
MSH6	-4891.0	-1596.0
MTA1	-1428.0	-2770.0
MTA2	-1000.0	4223.0
MTA3	3461.0	4368.0
MTOR	-4145.0	-2344.0
MTR	-7154.0	-1156.0
MTRR	-1959.0	968.0
MUC1	7970.0	3179.0
MUC13	3695.0	1168.0
MUC19	-1591.0	-6413.0
MUC20	3931.0	5255.0
MUC3A	4383.0	638.0
MUC4	-846.0	-343.0
MUC5B	1330.0	-4558.0
MUC6	3660.0	-6706.0
MUTYH	5944.5	-5831.5
MVB12A	5433.0	3851.0
MVB12B	-659.0	-5360.0
MYC	1892.0	3123.0
MYD88	-5933.0	3612.0
MYH9	7189.0	7115.0
MYO10	4745.0	-1478.0
MYO18A	467.0	-391.0
MYO1C	7502.0	5436.0
MYO5A	-7077.0	3216.0
MYO9B	1982.0	-237.0
NAGLU	-4620.0	-6515.0
NAPEPLD	-1672.0	169.0
NCAN	1112.0	-3927.0
NCBP1	-6452.0	5580.0
NCBP2	-6814.0	136.0
NCK1	-4610.0	8438.0
NCKAP1	-5953.0	8521.0
NCKAP1L	-1592.0	4630.0
NCKIPSD	7238.0	-4983.0
NCOR1	-7262.0	6244.0
NCOR2	-225.0	-3484.0
NCSTN	6534.0	860.0
NDC1	6665.0	-1084.0
NEDD4L	1323.0	-3476.0
NEIL1	6216.0	-6171.0
NEIL3	3195.0	-5023.0
NELFA	-3692.0	4383.0
NELFB	-4499.0	-5790.0
NELFCD	6086.0	1592.0
NELFE	-2178.0	4789.0
NEU1	-4896.0	-6581.0
NEURL1	1642.0	-2776.0
NEURL1B	6485.0	2017.0
NF1	-3237.0	5332.0
NFKB1	5449.0	4035.0
NFKB2	2120.0	-4751.0
NFKBIA	1631.0	4830.0
NHLRC1	670.0	-3827.0
NLRP3	-5337.0	1863.0
NMT1	-6059.0	6229.0
NMT2	2282.0	6516.0
NOS2	-1104.0	4079.0
NOTCH1	5759.0	5529.0
NOTCH2	-2318.0	-1775.0
NOTCH3	5224.0	1609.0
NOX1	-145.0	1132.0
NOXO1	530.0	-4544.0
NR3C1	-2732.0	2240.0
NR4A1	2903.0	3535.0
NRAS	3837.0	7903.0
NRG1	-2730.0	4749.0
NRG2	-1154.0	1668.0
NRG4	310.0	-4609.0
NT5E	-7042.0	7643.0
NTHL1	377.0	-3916.0
NUP107	3423.0	7169.0
NUP133	2759.0	-4113.0
NUP153	-4638.0	7763.0
NUP155	6347.0	2192.0
NUP160	-5230.0	1753.0
NUP188	3880.0	-4145.0
NUP205	855.0	6303.0
NUP210	8193.0	-4172.0
NUP214	7802.0	-5326.0
NUP35	-4374.0	-921.0
NUP37	3596.0	1004.0
NUP42	4998.0	-596.0
NUP43	-2270.0	3764.0
NUP50	-4961.0	641.0
NUP54	-3355.0	6010.0
NUP58	2230.0	7116.0
NUP62	4963.0	-4765.0
NUP85	1103.0	-4750.0
NUP88	4817.0	4002.0
NUP93	5331.0	6196.0
NUP98	-2590.0	5122.0
NUS1	-3128.0	2669.0
OGG1	6092.0	-1891.0
OGN	550.0	8729.0
OMD	-5697.0	7722.0
OPLAH	8134.0	-4469.0
OPN1SW	-197.0	-2540.0
OS9	-5615.0	3279.0
P2RX4	7060.0	-4339.0
P2RX7	4651.0	4591.0
PACS1	7765.0	5342.0
PAH	-6037.0	-1280.0
PAK2	-4906.0	6708.0
PAPSS1	-2058.0	4960.0
PAPSS2	7044.0	-2227.0
PARP1	134.0	473.0
PARP10	7711.0	-4684.0
PARP14	-5054.0	4222.0
PARP16	1718.0	-2509.0
PARP4	6474.0	-716.0
PARP6	3375.0	4640.0
PARP8	-7014.0	-116.0
PARP9	-2628.0	513.0
PC	-4135.0	-1520.0
PCCA	-6893.0	5127.0
PCCB	1319.0	4303.0
PDCD1	-3283.0	5216.0
PDGFA	4317.0	4142.0
PDGFB	-990.0	-1987.0
PDGFRA	7016.0	8193.0
PDGFRB	-1814.0	8544.0
PDPK1	-4074.0	1936.0
PDZD3	-5971.0	-5645.0
PGK1	-656.0	7226.0
PGM1	-1081.0	5048.0
PHB	312.0	5340.0
PHF21A	-2368.0	829.0
PIK3AP1	-6075.0	3775.0
PIK3C3	1518.0	-2612.0
PIK3CA	-6347.0	2923.0
PIK3CB	-1756.0	1880.0
PIK3CD	-1968.0	1889.0
PIK3R1	-839.0	8363.0
PIK3R2	1669.5	-3969.5
PIK3R3	3779.5	8820.5
PIK3R4	4272.0	-1214.0
PLCG1	8067.0	-4962.0
PLCG2	-5287.0	2474.0
PLK2	7974.0	8574.0
PML	6152.0	-5597.0
PMM2	-447.0	-333.0
POLR2A	4937.0	-1941.0
POLR2B	-675.0	5037.0
POLR2C	2928.0	6859.0
POLR2D	-2762.0	6076.0
POLR2E	7128.0	-3504.0
POLR2F	6184.0	-3058.0
POLR2G	3306.0	-3566.0
POLR2H	4359.0	-4161.0
POLR2I	5890.0	6864.0
POLR2J	1742.0	3424.0
POLR2K	1098.0	7632.0
POLR2L	3697.0	-3808.0
POM121	3732.5	-6552.5
POM121C	3732.5	-6552.5
POMC	3685.0	-2222.0
POMGNT1	-1550.0	1400.0
POMT1	5670.0	-6064.0
POMT2	-591.0	-5247.0
PORCN	3989.0	-4031.0
PPIA	4868.0	-469.0
PPP1CB	-4617.0	8661.0
PPP1CC	6108.0	2839.0
PPP1R3C	6926.0	-1003.0
PPP2CA	-5725.0	8237.0
PPP2CB	5588.0	159.0
PPP2R1A	6355.0	3115.0
PPP2R1B	-6463.0	4855.0
PPP2R5A	7319.0	1089.0
PPP2R5B	627.0	5414.0
PPP2R5C	3181.0	8384.0
PPP2R5D	2088.0	5911.0
PPP2R5E	5001.0	2898.0
PRDX1	-6422.0	8698.0
PRDX2	4337.0	4730.0
PRELP	4400.0	8732.0
PRKACA	-530.0	15.0
PRKACB	569.0	661.0
PRKAR1A	3942.0	6647.0
PRKAR1B	6901.0	5113.0
PRKAR2A	5319.0	7462.0
PRKAR2B	-2382.0	-990.0
PRKCSH	-4469.0	-2597.0
PRKX	2536.5	8246.5
PRR5	-6098.0	-5369.0
PSEN1	-7020.0	6996.0
PSEN2	-3057.0	-1025.0
PSENEN	-3656.0	5812.0
PSIP1	-6597.0	7229.0
PSMA1	-6705.0	7838.0
PSMA2	-5464.5	6058.5
PSMA3	-3145.0	7801.0
PSMA4	-6074.0	4688.0
PSMA5	-6660.0	4497.0
PSMA6	-1954.0	8445.0
PSMA7	1612.0	7052.0
PSMA8	649.0	-4004.0
PSMB1	-5281.0	5936.0
PSMB10	3752.0	-908.0
PSMB11	1977.0	-5501.0
PSMB2	1472.0	-4144.0
PSMB3	-3388.0	5539.0
PSMB4	-4941.0	-5852.0
PSMB5	-1638.0	-2409.0
PSMB6	1806.0	-1845.0
PSMB7	-4628.0	-657.0
PSMB8	1080.0	-3793.0
PSMB9	5987.0	-4708.0
PSMC1	-1312.0	4327.0
PSMC2	-6765.0	4648.0
PSMC3	-4285.0	3386.0
PSMC4	-6423.0	7920.0
PSMC5	-4831.0	1120.0
PSMC6	-6851.0	8666.0
PSMD1	-6497.0	8619.0
PSMD10	-1613.0	2576.0
PSMD11	-6873.0	5201.0
PSMD12	-6149.0	8628.0
PSMD13	1898.0	5044.0
PSMD14	-6080.0	8262.0
PSMD2	-6702.0	-3836.0
PSMD3	-2532.0	-3242.0
PSMD4	-5648.0	4994.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
PSMD7	-6943.0	7625.0
PSMD8	1978.0	7546.0
PSMD9	7707.5	-894.5
PSME1	2907.0	5905.0
PSME2	1270.0	-4595.0
PSME3	752.0	7366.0
PSME4	-6830.0	8511.0
PSMF1	5087.0	4771.0
PSTPIP1	-1224.0	-988.0
PTEN	-5726.0	8365.0
PTGDR	938.0	-1929.0
PTGER2	-614.0	-282.0
PTGER4	2504.0	1265.0
PTGES3	-7067.0	8733.0
PTGIR	-5223.0	4227.0
PTH1R	-5755.0	-4442.0
PTK2	2264.0	6997.0
PTPN11	-3946.0	6142.0
PTPN12	-2782.0	8454.0
PYCARD	6548.0	-4704.0
QKI	-6268.0	8165.0
RAB5A	1537.0	7332.0
RAB7A	-5898.0	8083.0
RAC1	-1258.0	4008.0
RAC2	-3191.0	6081.0
RAE1	3041.0	-1934.0
RAF1	-6377.0	2465.0
RAMP1	-1058.0	6011.0
RAMP2	4827.0	-1533.0
RAMP3	-4098.0	6226.0
RAN	-4369.0	1437.0
RANBP1	-564.0	4423.0
RANBP2	-4575.0	8132.0
RANGAP1	-2328.0	-1549.0
RAP1A	-6787.0	8805.0
RAP1B	942.0	8759.0
RB1	7982.0	7013.0
RBBP4	-6148.0	5835.0
RBBP7	2154.0	6750.0
RBP1	-60.0	5045.0
RBP4	5187.0	5087.0
RBPJ	2571.0	4528.0
RBX1	-391.0	3201.0
RCC1	-3025.0	-5367.0
RCOR1	-6714.0	3288.0
RDH12	-3849.0	788.0
RDH5	-4280.0	-4238.0
RELA	2579.0	-2368.0
REST	3620.0	4343.0
RFT1	5663.5	-3801.5
RHAG	-4309.0	5142.0
RHBDF2	5334.0	-1261.0
RHOG	2039.0	1654.0
RICTOR	493.0	4810.0
RIPK1	-2977.0	5088.0
RLN2	2347.5	469.5
RNF185	2705.0	5366.0
RNF213	-6529.0	-265.0
RNF43	5429.5	-2614.5
RNF5	-1555.0	-4449.0
RNGTT	-3753.0	6441.0
RNMT	-3077.0	5647.0
ROCK1	-2765.0	8654.0
ROCK2	-1368.0	8738.0
RPIA	-2267.0	-1161.0
RPL11	5748.0	1403.0
RPL12	6107.0	-5604.0
RPL13	5686.0	-3760.0
RPL14	5110.0	-1875.0
RPL18	2523.0	-625.0
RPL18A	4545.0	-3218.0
RPL19	4654.0	6782.0
RPL21	-1686.0	8463.0
RPL22	2365.0	459.0
RPL22L1	-5123.0	-6294.0
RPL23	-205.0	4253.0
RPL24	-409.0	6813.0
RPL26	3650.0	8722.0
RPL28	6714.0	4753.0
RPL29	2613.0	4628.0
RPL3	5378.0	1155.0
RPL30	4372.0	3664.0
RPL31	6732.0	-1507.0
RPL32	2989.0	8728.0
RPL34	661.0	7140.0
RPL35	5949.0	8834.0
RPL35A	-1509.0	6565.0
RPL36	7543.0	-2424.0
RPL36A	-5983.0	4837.0
RPL36AL	1793.0	-2074.0
RPL37	2109.0	-667.0
RPL38	5601.0	5675.0
RPL3L	-5986.0	4937.0
RPL4	2582.0	8471.0
RPL6	572.0	7594.0
RPL7	-5186.0	8598.0
RPL8	3526.0	820.0
RPLP2	3550.0	3555.0
RPN1	-7121.0	7464.0
RPN2	-5521.0	3974.0
RPS13	7174.0	315.0
RPS14	4070.0	4443.0
RPS15	7253.0	6174.0
RPS16	6244.0	1119.0
RPS17	5667.0	7685.0
RPS18	4253.0	-526.0
RPS19	6565.0	-1215.0
RPS2	7322.0	4216.0
RPS21	7111.0	-6494.0
RPS25	4261.0	8455.0
RPS27A	-133.0	-1807.0
RPS28	7208.0	-396.0
RPS3	2340.0	4381.0
RPS3A	-3115.0	8824.0
RPS4X	2522.0	7391.0
RPS5	3848.0	7515.0
RPS6	-1700.0	8603.0
RPS6KB2	3493.0	-2458.0
RPS8	3874.0	7646.0
RPS9	-1719.0	-2555.0
RXFP1	-1082.0	-4426.0
S1PR1	4311.0	7637.0
SAP18	-2023.0	7183.0
SAP30	-6527.0	3941.0
SAP30L	-2917.0	-2070.0
SBSPON	-4153.0	3078.0
SCTR	-219.0	-1332.0
SDC1	6076.0	6227.0
SDC2	-6850.0	7623.0
SDC3	5919.0	4486.0
SDC4	6585.0	816.0
SEC13	-1432.0	3604.0
SEH1L	2204.0	6910.0
SEL1L	-7264.0	7670.0
SEMA5A	-5557.0	182.0
SEMA5B	3538.0	-4929.0
SERPING1	3751.0	8403.0
SFPQ	-5196.0	-4828.0
SFTPD	2896.0	3018.0
SGSH	-3029.0	-5401.0
SH3GL1	993.0	-4650.0
SH3GL2	-6503.0	867.0
SH3KBP1	3805.0	5866.0
SHC1	568.0	1962.0
SHH	-4143.0	-5003.0
SHOC2	-5120.0	8378.0
SIGMAR1	178.0	-2004.0
SIN3A	4581.0	6116.0
SKP1	-6803.0	8394.0
SKP2	5738.0	-4232.0
SLC11A2	-6664.0	-6582.0
SLC12A1	-1145.0	903.0
SLC12A3	6051.0	-4654.0
SLC12A6	-1129.0	4183.0
SLC16A1	-7027.0	5763.0
SLC17A5	2333.0	243.0
SLC17A8	3580.0	-5201.0
SLC1A1	-5771.0	283.0
SLC1A3	5223.0	421.0
SLC20A2	6439.0	-1513.0
SLC22A12	-7212.0	-2532.0
SLC22A18	-5748.0	-4507.0
SLC22A5	7906.0	-6776.0
SLC24A1	2223.0	-5550.0
SLC24A4	1931.0	-1458.0
SLC24A5	-4336.0	-2669.0
SLC25A4	7196.0	-656.0
SLC25A5	7651.0	6887.0
SLC26A2	4919.0	406.0
SLC26A3	2391.0	-6227.0
SLC26A4	-3154.0	-406.0
SLC27A4	-1022.0	-5708.0
SLC29A3	-6489.0	62.0
SLC2A1	6575.0	1160.0
SLC2A10	-2881.0	7772.0
SLC2A2	7902.0	2301.0
SLC2A9	8222.0	3166.0
SLC33A1	-7189.0	3144.0
SLC34A1	-4925.0	-5775.0
SLC34A2	1862.0	3377.0
SLC34A3	-4440.0	-3042.0
SLC35A1	-5778.0	918.0
SLC35A2	2888.0	-5791.0
SLC35A3	-2157.0	4799.0
SLC35C1	-399.0	-4005.0
SLC35D1	7505.0	-5061.0
SLC36A2	856.0	-4025.0
SLC37A4	5992.0	2463.0
SLC39A4	4241.0	-90.0
SLC3A1	-3746.0	1921.0
SLC3A2	7436.0	1396.0
SLC40A1	7465.0	6161.0
SLC4A1	944.0	-1091.0
SLC4A4	5877.0	2616.0
SLC5A1	7441.0	3409.0
SLC5A2	-269.0	-5668.0
SLC6A18	-5071.0	-1023.0
SLC6A19	8163.0	-4413.0
SLC6A2	-1171.0	2022.0
SLC6A20	5450.0	-6763.0
SLC6A5	6520.0	-6245.0
SLC7A7	6551.0	-5468.0
SLC7A9	6467.0	-6401.0
SLC9A6	-2948.0	4059.0
SLC9A9	-3428.0	1385.0
SLCO2A1	7840.0	2219.0
SMAD2	2671.0	7154.0
SMAD3	-1639.0	-2520.0
SMAD4	3068.0	901.0
SND1	-6474.0	-3181.0
SNF8	2397.0	-3270.0
SNW1	2102.0	8287.0
SOD2	-1635.0	4013.0
SOS1	-6566.0	7698.0
SPON1	8083.0	8251.0
SPON2	1919.0	3082.0
SPRED1	-6354.0	8554.0
SPRED2	-1328.0	-5582.0
SPRED3	3740.0	3539.0
SRC	-2657.0	-1643.0
SRD5A3	-2854.0	4649.0
SSRP1	2663.0	4754.0
ST3GAL1	3065.0	8669.0
ST3GAL2	6089.0	121.0
ST3GAL3	-3090.0	3648.0
ST3GAL4	-1264.0	1193.0
ST6GAL1	4830.0	6368.0
ST6GALNAC2	-6427.0	-3901.0
ST6GALNAC3	4083.0	6940.0
ST6GALNAC4	-365.0	4860.0
STAM	-2360.0	4932.0
STAM2	494.0	2564.0
STAT1	-3464.0	-4440.0
STAT2	4437.0	-4922.0
STAT3	8126.0	4982.0
STAT5A	2714.0	-3795.0
STAT5B	4664.0	-4634.0
STRA6	6283.0	-3159.0
STRN	-4029.0	6779.0
STT3A	-6845.0	4709.0
STX1A	2774.0	-2559.0
STX1B	3559.0	374.0
SUDS3	2620.0	2169.0
SUGT1	3448.0	6681.0
SUMO1	-4690.0	8345.0
SUPT16H	-1751.0	7746.0
SUPT4H1	3573.0	2203.0
SUPT5H	5137.0	2571.0
SUZ12	-1028.0	8662.0
SV2A	6774.0	-1791.0
SV2C	-3739.0	-1283.0
SYK	-6921.0	4480.0
SYT1	-2989.0	-4969.0
SYT2	-2226.0	-4027.0
SYVN1	-7005.0	-3045.0
TAF1	-3038.5	3979.5
TAF10	-3030.0	2638.0
TAF11	3706.0	-6076.0
TAF12	-5685.0	2641.0
TAF13	-4258.0	1970.0
TAF15	-1144.0	2020.0
TAF1L	-3038.5	3979.5
TAF2	-5611.0	6188.0
TAF3	1245.0	3100.0
TAF4	2448.0	3472.0
TAF4B	6609.0	4831.0
TAF5	863.0	-388.0
TAF6	-2810.0	1885.0
TAF7	-5754.0	6658.0
TAF9	-3421.0	8678.0
TAF9B	-362.0	4853.0
TALDO1	-5386.0	449.0
TBK1	-5003.0	4897.0
TBL1X	-7106.5	7510.5
TBL1XR1	-1156.0	6145.0
TBP	3907.0	-217.0
TBXAS1	-7074.0	-5151.0
TCEA1	-5628.0	8792.0
TCF7L2	-4057.0	-2326.0
TCN2	-6559.0	2042.0
TENT4A	-2007.0	-3938.0
TFDP1	-6289.0	4476.0
TFDP2	7449.0	3780.0
TGFA	4979.0	2380.0
TGFB1	-1851.0	6152.0
TGFBR1	-2001.0	7866.0
TGFBR2	930.0	7719.0
THBS1	8000.0	8780.0
THBS2	-3256.0	8633.0
THSD1	7418.0	2048.0
THSD4	5121.0	4561.0
THSD7A	2585.0	6050.0
THSD7B	-3715.0	-1612.0
TICAM1	-1539.0	-3874.0
TIRAP	-3143.0	6369.0
TLN1	-2076.0	-2832.0
TLR1	-3224.0	560.0
TLR2	5407.0	5188.0
TLR3	1181.0	6018.0
TLR4	-4128.0	8470.0
TLR6	-4778.0	7142.0
TLR7	-3743.0	5769.0
TLR9	-3935.5	846.5
TMPRSS2	7909.0	4409.0
TNKS	7493.0	2959.0
TNKS2	-3624.0	4091.0
TPMT	-2094.0	4118.0
TPR	-4239.0	8611.0
TPST1	-1632.0	2591.0
TPST2	5077.0	-171.0
TRADD	-1318.0	-2687.0
TRAF2	3405.0	-3806.0
TRAF3	-6416.0	5442.0
TRAK1	7905.0	-999.0
TRAT1	-2279.0	-5760.0
TRIM24	5518.0	4599.0
TRIM27	-452.0	-3380.0
TRIM28	-1390.0	-6154.0
TSC2	5344.0	-2751.0
TSG101	-708.0	7980.0
TSHB	5602.0	-4369.0
TSHR	3113.0	5679.0
TTR	-6090.0	3451.0
TUBB	335.0	8036.0
TUSC3	-5686.0	4758.0
TXN	-5397.0	-2909.0
TXNIP	2986.0	4021.0
TXNRD1	-3425.0	4896.0
TYK2	3318.0	-6265.0
UBA52	7488.0	-4269.0
UBAP1	-6158.0	7653.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
UBE2C	733.0	-1864.0
UBE2D1	5638.0	3025.0
UBE2E1	-6831.0	8405.0
UBE2I	5599.0	2810.0
UBE2S	4549.0	-1742.0
UGT1A1	8194.0	-551.0
UGT1A4	8254.0	-5328.0
UNC93B1	-2571.0	-565.0
UVRAG	-5823.0	-64.0
VAMP1	6428.0	-5633.0
VAMP2	8086.5	-3275.5
VAV1	-4395.0	5076.0
VAV2	2432.0	-843.0
VAV3	6942.0	5027.0
VCAN	-3773.0	1454.0
VCL	-4796.0	7947.0
VCP	-7069.0	5449.0
VEGFA	-4619.0	-5156.0
VIPR1	776.0	8356.0
VIPR2	173.0	915.0
VPS25	-306.0	6834.0
VPS28	4871.0	5243.0
VPS33B	2918.5	-5911.5
VPS36	5728.0	8042.0
VPS37A	-5968.0	8308.0
VPS37B	5639.0	2161.0
VPS37C	5395.0	-224.0
VPS37D	-1556.0	-3123.0
VPS4A	-5731.5	7213.5
VPS4B	2398.0	6175.0
VTA1	-2777.0	104.0
VWF	7704.0	-1950.0
WAS	-11.0	299.0
WASF1	-5233.0	-3651.0
WASF2	4804.0	1618.0
WASF3	4712.0	680.0
WASL	-3989.0	7855.0
WDR48	-2737.0	3854.0
WIPF1	-3718.0	7829.0
WIPF2	4034.0	-1247.0
WIPF3	7332.0	3435.0
WNT5A	5498.0	-739.0
XPO1	-6543.0	7447.0
XRCC4	-4715.0	7026.0
XRCC5	-2388.0	162.0
XRCC6	-1971.0	4034.0
YES1	-120.0	7265.0
YWHAB	-4723.0	8579.0
YWHAE	-2079.0	7315.0
ZBP1	-6151.0	4520.0
ZC3HAV1	-469.0	-613.0
ZCRB1	3718.0	5429.0
ZFYVE9	-3503.0	7936.0
ZMYM2	-4816.0	6346.0

---

---

Metabolism of RNA

Metabolism of RNA

metric	value
setSize	629
pMANOVA	2.03e-14
p.adjustMANOVA	2.85e-12
s.dist	0.201
s.diabetes	-0.0931
s.mitoG	0.178
p.diabetes	7.4e-05
p.mitoG	3.92e-14

Top 20 genes

Gene	diabetes	mitoG
HNRNPC	-7051.0	8787.0
HNRNPA3	-6985.0	8827.0
THOC7	-7038.0	8659.0
PAPOLA	-7187.0	8340.0
HSPA8	-7307.0	8180.0
DHX15	-6821.0	8710.0
PSMC6	-6851.0	8666.0
UBB	-7104.0	8341.0
PSME4	-6830.0	8511.0
PSMD1	-6497.0	8619.0
UPF2	-6949.0	7960.0
HSPB1	-6918.0	7890.0
GSPT1	-6653.0	8055.0
PSMD12	-6149.0	8628.0
HSPA1A	-7272.5	7293.5
CDC5L	-6323.0	8388.0
PSMD7	-6943.0	7625.0
PSMA1	-6705.0	7838.0
CCAR1	-6647.0	7887.0
GTF2H1	-6106.0	8498.0

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
A1CF	-7229.0	5712.0
AAAS	5561.0	-2261.0
ACTB	-4152.0	7953.0
ADAR	4854.0	-5902.0
ADARB1	7383.0	5666.0
ADAT1	-901.0	-4626.0
ADAT2	-572.0	-641.0
ADAT3	4538.0	-6344.0
AKT1	4859.0	7244.0
ALKBH8	-3772.0	2897.0
ALYREF	-1610.0	-1688.0
ANP32A	3020.5	6935.5
APOBEC1	2028.0	4529.0
APOBEC2	-868.0	5863.0
APOBEC3H	794.0	-3298.0
APOBEC4	3338.0	-2304.0
AQR	-3719.0	8047.0
BCAS2	255.0	-780.0
BMS1	-5831.0	3306.0
BOP1	-3585.0	976.0
BUD31	-4840.0	8703.0
BYSL	-4542.0	5843.0
C1D	-5321.0	8041.0
C2orf49	-4813.0	6927.0
CASC3	-1205.0	-683.0
CCAR1	-6647.0	7887.0
CCNH	-5547.0	6108.0
CD2BP2	5662.0	-4064.0
CD44	-4381.0	6982.0
CDC40	1666.0	5218.0
CDC5L	-6323.0	8388.0
CDK7	-258.0	3661.0
CDKAL1	-231.0	6855.0
CHERP	5491.0	-5010.0
CHTOP	-4615.0	-1316.0
CLNS1A	-2264.0	5698.0
CLP1	4455.0	-5275.0
CNOT1	-2585.0	3418.0
CNOT10	5730.0	-417.0
CNOT11	-5473.0	1110.0
CNOT2	-4597.0	3701.0
CNOT3	1322.0	-5732.0
CNOT4	-4789.0	6329.0
CNOT6	-5929.0	7904.0
CNOT6L	2567.0	6299.0
CNOT7	-4683.0	3410.0
CNOT8	-2638.0	1142.0
CPSF1	4436.0	-5953.0
CPSF2	-6146.0	6450.0
CPSF3	3877.0	5804.0
CPSF4	-267.0	514.0
CPSF7	-2248.0	-5214.0
CRNKL1	-4930.0	8053.0
CSNK1D	-1602.0	2506.0
CSNK1E	5383.5	5055.5
CSTF1	3995.0	1240.0
CSTF2	-3554.0	7108.0
CSTF2T	-3561.0	3385.0
CSTF3	-6512.0	-1154.0
CTNNBL1	5304.0	2114.0
CTU1	6371.0	-3735.0
CTU2	3801.0	-5802.0
CWC15	-5194.0	8607.0
CWC22	509.0	6448.0
CWC25	1034.0	5526.0
CWC27	6648.0	5720.0
DCAF13	-6109.0	5418.0
DCP1A	2574.0	-178.0
DCP1B	6434.0	-6249.0
DCP2	-4513.0	2966.0
DCPS	-4609.0	5600.0
DDX1	-3045.0	6963.0
DDX20	976.0	4663.0
DDX21	-5116.0	8276.0
DDX23	1901.0	-2052.0
DDX39A	-5476.0	-2152.0
DDX39B	4289.0	-5871.0
DDX42	3392.0	2416.0
DDX46	5751.0	4654.0
DDX47	3030.0	755.0
DDX49	4404.0	-1145.0
DDX5	-3313.0	-2478.0
DDX52	-4060.0	7194.0
DDX6	-4502.0	5780.0
DHX15	-6821.0	8710.0
DHX16	-2734.0	-2018.0
DHX37	-533.0	-1936.0
DHX38	3912.0	-1919.0
DHX9	-4354.0	8508.0
DIMT1	2968.0	-3709.0
DIS3	-6175.0	6931.0
DKC1	-5095.0	7179.0
DNAJC8	4687.0	7945.0
DUS2	-854.0	-2803.0
EBNA1BP2	-2177.0	6468.0
EDC3	2336.0	1124.0
EDC4	4345.0	-3702.0
EFTUD2	1129.0	2551.0
EIF4A1	5335.0	61.0
EIF4A2	-6848.0	-699.0
EIF4A3	2375.0	2229.0
EIF4B	-4266.0	-945.0
EIF4E	-4500.0	8429.0
EIF4G1	-5996.0	5731.0
ELAC2	3639.0	1857.0
ELAVL1	-6989.0	3842.0
EMG1	-6093.0	-1167.0
ENPP2	1844.0	7459.0
EPRS1	-5855.0	8062.0
ERCC2	6295.0	-6411.0
ERCC3	-2263.0	1771.0
ERI1	-5053.0	4453.0
ETF1	-3268.0	8174.0
EXOSC1	-2448.0	7613.0
EXOSC10	1760.0	8346.0
EXOSC2	3957.0	3800.0
EXOSC3	-1469.0	-3935.0
EXOSC4	-3182.0	-4923.0
EXOSC5	4223.0	-3378.0
EXOSC7	6973.0	-5606.0
EXOSC8	6788.0	616.0
EXOSC9	4661.0	7068.0
FAM98B	2418.0	-4160.0
FAU	6809.0	7710.0
FBL	6041.0	-6202.0
FTSJ1	-914.0	3461.0
FTSJ3	364.0	-330.0
FUS	8128.0	-5908.0
FYTTD1	-1268.0	8265.0
GAR1	642.0	-352.0
GCFC2	2615.0	-4506.0
GEMIN2	2981.0	2254.0
GEMIN4	886.0	-850.0
GEMIN5	2645.0	-586.0
GEMIN6	779.0	3452.0
GEMIN7	-3021.0	21.0
GEMIN8	-341.0	-1800.0
GLE1	-1677.0	-2245.0
GNL3	-4340.0	6867.0
GPKOW	1066.0	7827.0
GPRC5A	-2287.0	6401.0
GSPT1	-6653.0	8055.0
GSPT2	-1500.0	-264.0
GTF2F1	373.0	6337.0
GTF2F2	-1458.0	7912.0
GTF2H1	-6106.0	8498.0
GTF2H2	-3368.5	7043.5
GTF2H3	-1824.0	-2008.0
GTF2H4	3818.0	-4105.0
GTF2H5	1998.0	783.0
GTPBP3	2875.0	-5140.0
HBS1L	-4957.0	1647.0
HEATR1	-6514.0	7682.0
HNRNPA0	8106.0	-5703.0
HNRNPA1	7891.0	-6290.0
HNRNPA2B1	-2132.0	-151.0
HNRNPA3	-6985.0	8827.0
HNRNPC	-7051.0	8787.0
HNRNPD	6599.0	1068.0
HNRNPF	-4812.0	5595.0
HNRNPH1	-6127.0	-3386.0
HNRNPH2	-5391.0	5932.0
HNRNPK	-808.0	7246.0
HNRNPL	322.0	2108.0
HNRNPM	-6548.0	-2929.0
HNRNPR	-3972.0	1045.0
HNRNPU	-5219.0	7082.0
HNRNPUL1	4431.0	1071.0
HSD17B10	3539.0	5976.0
HSPA1A	-7272.5	7293.5
HSPA8	-7307.0	8180.0
HSPB1	-6918.0	7890.0
IGF2	-4212.0	5578.0
IGF2BP1	-7315.0	4141.0
IGF2BP2	1777.0	3236.0
IGF2BP3	-2484.0	-3959.0
IMP3	3952.0	-6093.0
IMP4	186.0	5570.0
ISG20L2	-4479.0	3406.0
ISY1	-241.5	-1365.5
KHSRP	-2184.0	-6452.0
KRR1	-4385.0	7088.0
LAGE3	5065.0	1002.0
LAS1L	1684.0	1715.0
LCMT2	-6209.0	-5817.0
LSM1	1559.0	3093.0
LSM10	-4491.0	-4047.0
LSM11	1126.0	-4314.0
LSM2	-5379.0	2908.0
LSM3	2945.0	6498.0
LSM4	2117.0	1014.0
LSM5	2584.0	604.0
LSM6	-1018.0	7823.0
LSM7	1816.0	4105.0
LSM8	6248.0	-1669.0
LTV1	-279.5	6894.5
MAGOH	-2387.0	7841.0
MAGOHB	1654.0	1040.0
MAPK11	4349.0	2889.0
MAPK14	-6337.0	-1012.0
MAPKAPK2	-2527.0	4587.0
METTL1	-871.0	-234.0
METTL14	-529.0	135.0
METTL3	-6811.0	-3691.0
MNAT1	1928.0	4358.0
MPHOSPH10	-5904.0	8696.0
MPHOSPH6	-3203.0	7923.0
MRM1	6500.0	-222.0
MRM2	-3612.0	-2742.0
MRM3	2274.0	3059.0
MT-ATP6	-5818.0	8744.0
MT-ATP8	3277.0	6153.0
MT-CO1	6781.0	5983.0
MT-CO2	293.0	-1711.0
MT-CO3	2273.0	6269.0
MT-CYB	3577.0	8110.0
MT-ND1	5618.0	7323.0
MT-ND2	-1693.0	8626.0
MT-ND3	1835.0	8689.0
MT-ND4	1752.0	7883.0
MT-ND4L	2829.0	8068.0
MT-ND5	6025.0	8007.0
MT-ND6	5059.0	8045.0
MTERF4	-6002.0	2934.0
MTO1	-6215.0	1994.0
MTREX	-6973.0	5247.0
MYC	1892.0	3123.0
NAT10	2042.0	-2361.0
NCBP1	-6452.0	5580.0
NCBP2	-6814.0	136.0
NCL	6850.0	8762.0
NDC1	6665.0	-1084.0
NHP2	-5332.0	6281.0
NIP7	5420.0	6991.0
NOB1	-3003.0	2527.0
NOC4L	5961.0	1908.0
NOL11	-4046.0	6580.0
NOL12	-3477.5	6109.5
NOL6	7943.0	-3108.0
NOL9	-1832.0	-148.0
NOP10	2308.0	5890.0
NOP14	-2312.0	6526.0
NOP56	-875.0	1129.0
NOP58	-4438.0	5964.0
NSUN2	6682.0	6335.0
NSUN4	1070.0	-2056.0
NSUN6	2376.0	2933.0
NT5C3B	5089.0	1939.0
NUDT21	4767.0	-2089.0
NUP107	3423.0	7169.0
NUP133	2759.0	-4113.0
NUP153	-4638.0	7763.0
NUP155	6347.0	2192.0
NUP160	-5230.0	1753.0
NUP188	3880.0	-4145.0
NUP205	855.0	6303.0
NUP210	8193.0	-4172.0
NUP214	7802.0	-5326.0
NUP35	-4374.0	-921.0
NUP37	3596.0	1004.0
NUP42	4998.0	-596.0
NUP43	-2270.0	3764.0
NUP50	-4961.0	641.0
NUP54	-3355.0	6010.0
NUP58	2230.0	7116.0
NUP62	4963.0	-4765.0
NUP85	1103.0	-4750.0
NUP88	4817.0	4002.0
NUP93	5331.0	6196.0
NUP98	-2590.0	5122.0
NXF1	-6200.0	-3821.0
NXT1	1194.0	-2312.0
OSGEP	1999.0	983.0
PABPC1	-949.0	6861.0
PAIP1	-5807.0	8319.0
PAN2	2594.0	-6407.0
PAN3	-2601.0	-386.0
PAPOLA	-7187.0	8340.0
PARN	7135.0	-1655.0
PATL1	-5893.0	5767.0
PCBP1	-6097.0	-710.0
PCBP2	6135.0	1313.0
PCF11	2261.0	2780.0
PDCD11	-4002.0	-3015.0
PDCD7	5822.0	-4855.0
PELP1	1681.0	-4851.0
PES1	2890.0	6091.0
PHAX	-2866.0	7959.0
PHF5A	-4416.0	-1224.0
PLRG1	-2992.0	3501.0
PNO1	-5524.0	8385.0
PNRC2	-2675.0	8726.0
POLDIP3	748.0	309.0
POLR2A	4937.0	-1941.0
POLR2B	-675.0	5037.0
POLR2C	2928.0	6859.0
POLR2D	-2762.0	6076.0
POLR2E	7128.0	-3504.0
POLR2F	6184.0	-3058.0
POLR2G	3306.0	-3566.0
POLR2H	4359.0	-4161.0
POLR2I	5890.0	6864.0
POLR2J	1742.0	3424.0
POLR2K	1098.0	7632.0
POLR2L	3697.0	-3808.0
POM121	3732.5	-6552.5
POM121C	3732.5	-6552.5
POP1	-6227.0	-4247.0
POP4	7301.0	6835.0
POP5	-3544.0	-3154.0
POP7	943.0	-268.0
PPIE	6275.0	-5627.0
PPIL1	-5545.0	4797.0
PPIL4	-2658.0	5395.0
PPIL6	3986.0	3821.0
PPP2CA	-5725.0	8237.0
PPP2R1A	6355.0	3115.0
PPP2R2A	-3055.0	7888.0
PPWD1	-2393.0	2244.0
PQBP1	-4962.0	8189.0
PRCC	-3064.0	-3244.0
PRKCA	-6271.0	3380.0
PRKCD	365.0	1901.0
PRMT5	-2753.0	1830.0
PRORP	-4253.5	5249.5
PRPF19	628.0	2226.0
PRPF3	-4119.0	5240.0
PRPF31	-387.0	4117.0
PRPF38A	3632.0	5923.0
PRPF4	-4040.0	1952.0
PRPF40A	1636.0	8680.0
PRPF6	3568.0	279.0
PRPF8	947.0	5393.0
PSMA1	-6705.0	7838.0
PSMA2	-5464.5	6058.5
PSMA3	-3145.0	7801.0
PSMA4	-6074.0	4688.0
PSMA5	-6660.0	4497.0
PSMA6	-1954.0	8445.0
PSMA7	1612.0	7052.0
PSMA8	649.0	-4004.0
PSMB1	-5281.0	5936.0
PSMB10	3752.0	-908.0
PSMB11	1977.0	-5501.0
PSMB2	1472.0	-4144.0
PSMB3	-3388.0	5539.0
PSMB4	-4941.0	-5852.0
PSMB5	-1638.0	-2409.0
PSMB6	1806.0	-1845.0
PSMB7	-4628.0	-657.0
PSMB8	1080.0	-3793.0
PSMB9	5987.0	-4708.0
PSMC1	-1312.0	4327.0
PSMC2	-6765.0	4648.0
PSMC3	-4285.0	3386.0
PSMC4	-6423.0	7920.0
PSMC5	-4831.0	1120.0
PSMC6	-6851.0	8666.0
PSMD1	-6497.0	8619.0
PSMD10	-1613.0	2576.0
PSMD11	-6873.0	5201.0
PSMD12	-6149.0	8628.0
PSMD13	1898.0	5044.0
PSMD14	-6080.0	8262.0
PSMD2	-6702.0	-3836.0
PSMD3	-2532.0	-3242.0
PSMD4	-5648.0	4994.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
PSMD7	-6943.0	7625.0
PSMD8	1978.0	7546.0
PSMD9	7707.5	-894.5
PSME1	2907.0	5905.0
PSME2	1270.0	-4595.0
PSME3	752.0	7366.0
PSME4	-6830.0	8511.0
PSMF1	5087.0	4771.0
PTBP1	-4264.0	-2729.0
PUF60	-754.0	731.0
PUS1	3104.0	-5968.0
PUS3	-4535.0	6560.0
PUS7	4984.0	2287.0
PWP2	4987.5	-4444.5
QTRT1	3026.0	-4577.0
QTRT2	540.0	4234.0
RAE1	3041.0	-1934.0
RAN	-4369.0	1437.0
RANBP2	-4575.0	8132.0
RBM17	-2667.0	6469.0
RBM22	2599.0	3856.0
RBM28	-5098.0	2336.0
RBM5	-5157.0	-3022.0
RBM8A	-4975.0	7751.0
RBMX	2760.5	863.5
RCL1	5218.0	4620.0
RIOK1	-1297.0	7015.0
RIOK2	-670.0	7303.0
RIOK3	-3202.0	8097.0
RNGTT	-3753.0	6441.0
RNMT	-3077.0	5647.0
RNPC3	3799.0	-3087.0
RNPS1	5559.0	6960.0
RPL11	5748.0	1403.0
RPL12	6107.0	-5604.0
RPL13	5686.0	-3760.0
RPL14	5110.0	-1875.0
RPL18	2523.0	-625.0
RPL18A	4545.0	-3218.0
RPL19	4654.0	6782.0
RPL21	-1686.0	8463.0
RPL22	2365.0	459.0
RPL22L1	-5123.0	-6294.0
RPL23	-205.0	4253.0
RPL24	-409.0	6813.0
RPL26	3650.0	8722.0
RPL28	6714.0	4753.0
RPL29	2613.0	4628.0
RPL3	5378.0	1155.0
RPL30	4372.0	3664.0
RPL31	6732.0	-1507.0
RPL32	2989.0	8728.0
RPL34	661.0	7140.0
RPL35	5949.0	8834.0
RPL35A	-1509.0	6565.0
RPL36	7543.0	-2424.0
RPL36A	-5983.0	4837.0
RPL36AL	1793.0	-2074.0
RPL37	2109.0	-667.0
RPL38	5601.0	5675.0
RPL3L	-5986.0	4937.0
RPL4	2582.0	8471.0
RPL6	572.0	7594.0
RPL7	-5186.0	8598.0
RPL8	3526.0	820.0
RPLP2	3550.0	3555.0
RPP14	-1705.0	2028.0
RPP21	1368.0	437.0
RPP25	5432.0	3890.0
RPP30	-4567.0	4289.0
RPP38	-3284.0	7004.0
RPP40	-5546.0	2654.0
RPPH1	7989.0	5594.0
RPS13	7174.0	315.0
RPS14	4070.0	4443.0
RPS15	7253.0	6174.0
RPS16	6244.0	1119.0
RPS17	5667.0	7685.0
RPS18	4253.0	-526.0
RPS19	6565.0	-1215.0
RPS2	7322.0	4216.0
RPS21	7111.0	-6494.0
RPS25	4261.0	8455.0
RPS27A	-133.0	-1807.0
RPS28	7208.0	-396.0
RPS3	2340.0	4381.0
RPS3A	-3115.0	8824.0
RPS4X	2522.0	7391.0
RPS5	3848.0	7515.0
RPS6	-1700.0	8603.0
RPS8	3874.0	7646.0
RPS9	-1719.0	-2555.0
RRP1	5293.0	6186.0
RRP36	3453.0	244.0
RRP7A	-1466.0	3721.0
RRP9	2614.0	851.0
RTCB	-1912.0	-1661.0
RTRAF	-2127.0	8772.0
SARNP	-72.0	4128.0
SART1	2632.0	-1920.0
SEC13	-1432.0	3604.0
SEH1L	2204.0	6910.0
SENP3	-2124.5	3519.5
SET	-4660.5	2403.5
SF1	-3744.0	-5004.0
SF3A1	-4724.0	-831.0
SF3A2	1864.0	-5244.0
SF3A3	-5745.0	4848.0
SF3B1	-4526.0	6504.0
SF3B2	2734.0	3698.0
SF3B3	2517.0	3638.0
SF3B4	2644.0	-4321.0
SF3B5	3362.0	-5461.0
SF3B6	-4244.0	8139.0
SKIV2L	3667.0	-6264.0
SLBP	621.0	1614.0
SLU7	-5701.0	8342.0
SMG1	-4496.0	2722.0
SMG5	-5805.0	-946.0
SMG6	4622.0	-3632.0
SMG7	-5421.0	7779.0
SMG9	5239.0	-2313.0
SMN1	-4174.5	4822.5
SMNDC1	-5830.0	8338.0
SNRNP200	-4151.0	749.0
SNRNP25	4727.0	2447.0
SNRNP27	-3139.0	7267.0
SNRNP35	-922.0	-2993.0
SNRNP40	4613.0	2666.0
SNRNP48	-5156.0	-5068.0
SNRNP70	2850.0	-6750.0
SNRPA	-5853.0	2728.0
SNRPA1	4691.0	-2581.0
SNRPB2	-4273.0	6411.0
SNRPC	5050.0	2270.0
SNRPD1	-4843.0	5990.0
SNRPD2	2697.0	71.0
SNRPD3	-4317.5	6353.5
SNRPE	-1708.0	-4752.0
SNRPF	6058.0	-6379.0
SNRPG	3050.0	-3586.0
SNRPN	-4895.0	6816.0
SNU13	-4083.0	7577.0
SNUPN	-2042.0	4519.0
SNW1	2102.0	8287.0
SRRM1	5551.0	7062.0
SRRM2	-4444.0	1604.0
SRRT	-6373.0	-1448.0
SRSF1	-4987.5	1828.5
SRSF10	-6704.0	7648.0
SRSF11	-284.0	-2825.0
SRSF2	6622.0	-6568.0
SRSF3	-5065.0	6799.0
SRSF4	5351.0	2820.0
SRSF5	7221.0	-6051.0
SRSF6	-4543.0	-3175.0
SRSF7	-4537.0	-3274.0
SRSF9	-2009.0	-5029.0
SUGP1	6015.0	1965.0
SUPT5H	5137.0	2571.0
SYF2	2285.0	3882.0
SYMPK	-1320.0	-3222.0
TBL3	5799.0	-3253.0
TEX10	5529.0	1840.0
TFB1M	-154.0	-4984.0
TFIP11	3490.0	2409.0
TGS1	-5959.0	7769.0
THADA	-2726.0	-5996.0
THG1L	-5958.0	649.0
THOC1	-3882.0	8049.0
THOC2	-4608.0	8069.0
THOC3	-108.0	5029.0
THOC5	-645.0	6207.0
THOC6	-3723.0	-3958.0
THOC7	-7038.0	8659.0
THUMPD1	-2693.0	6882.0
TNFSF13	2168.0	1972.0
TNKS1BP1	4615.0	471.0
TNPO1	-2733.0	6723.0
TP53RK	-488.0	-6739.0
TPR	-4239.0	8611.0
TPRKB	4020.0	-3573.0
TRA2B	-4663.0	6141.0
TRDMT1	7443.0	6358.0
TRIT1	-250.0	-5630.0
TRMT1	-1066.0	-6312.0
TRMT10A	-4078.0	-3656.0
TRMT10C	-5437.0	8416.0
TRMT11	391.0	-2363.0
TRMT112	-6614.0	-1009.0
TRMT12	652.0	-3227.0
TRMT13	2744.0	786.0
TRMT44	-1765.0	-1776.0
TRMT5	-1047.0	3389.0
TRMT6	4855.0	6909.0
TRMT61A	-852.0	-1474.0
TRMT9B	3223.0	4033.0
TRMU	666.0	-4049.0
TRNT1	-4756.0	6488.0
TSEN15	738.0	5492.0
TSEN2	2542.0	-2817.0
TSEN34	4877.0	-5675.0
TSEN54	4380.0	-815.0
TSR1	-4634.0	2623.0
TSR3	4228.0	-5856.0
TTC37	-5820.0	4022.0
TXNL4A	-4484.0	-2777.0
TYW1	3977.5	-5466.5
TYW3	-1557.0	441.0
TYW5	791.0	7689.0
U2AF1	-5248.5	5311.5
U2AF1L4	3053.0	-4856.0
U2AF2	-2150.0	-825.0
U2SURP	1276.0	7793.0
UBA52	7488.0	-4269.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
UPF1	-272.0	-4262.0
UPF2	-6949.0	7960.0
UPF3A	-1867.0	3076.0
UPF3B	3082.0	2946.0
URM1	6326.0	-2691.0
USP39	-6144.0	7056.0
UTP11	-3324.0	3075.0
UTP14A	-755.5	3859.5
UTP14C	-755.5	3859.5
UTP15	4856.0	6673.0
UTP18	1908.0	6014.0
UTP20	8200.0	5794.0
UTP3	-2706.0	6844.0
UTP4	-4384.0	4038.0
UTP6	-3727.0	5591.0
WBP4	-2230.0	4809.0
WDR12	-3943.0	1434.0
WDR18	-5000.0	-3150.0
WDR3	-6076.0	2575.0
WDR33	-4364.0	938.0
WDR36	5285.0	-1626.0
WDR4	-6102.0	-4331.0
WDR43	2708.0	8166.0
WDR46	5078.0	-4710.0
WDR61	2802.0	-446.0
WDR75	-3646.0	8219.0
WDR77	3198.0	-4739.0
WTAP	-3354.0	6889.0
XAB2	2873.0	3916.0
XPO1	-6543.0	7447.0
XPOT	-4751.0	5260.0
XRN1	7052.0	1866.0
XRN2	7433.0	6374.0
YWHAB	-4723.0	8579.0
YWHAZ	-5614.0	8512.0
ZBTB8OS	-4432.0	5855.0
ZC3H11A	-3061.5	-791.5
ZCRB1	3718.0	5429.0
ZFP36	-1295.0	1383.0
ZFP36L1	-5993.0	4405.0
ZMAT5	5560.0	-4410.0
ZNF473	-2403.0	679.0
ZRSR2	-3026.0	-200.0

---

---

Hemostasis

Hemostasis

metric	value
setSize	547
pMANOVA	1.75e-13
p.adjustMANOVA	2.22e-11
s.dist	0.19
s.diabetes	-0.00704
s.mitoG	0.189
p.diabetes	0.779
p.mitoG	4.52e-14

Top 20 genes

Gene	diabetes	mitoG
IGHV1-69	-7353.5	8845.5
IGKV4-1	-7301.0	8840.0
RAP1A	-6787.0	8805.0
CAPZA1	-6942.0	8474.0
HSPA5	-7309.0	7589.0
HDAC2	-6396.0	8620.0
ITGB1	-6241.0	8758.0
GNAI1	-6368.0	8547.0
ANGPT1	-6415.0	8155.0
SDC2	-6850.0	7623.0
MANF	-7276.0	7166.0
TMX3	-6086.0	8558.0
DOCK4	-7238.0	7101.0
IGKV5-2	-5895.0	8671.0
THBD	-6500.0	7788.0
SOS1	-6566.0	7698.0
TIMP3	-7266.0	6800.0
HGF	-6226.0	7929.0
DOCK10	-6602.0	7444.0
ATP2B1	-5922.0	8184.0

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
AAMP	69.0	-4287.0
ABCC4	8232.0	-1922.0
ABHD12	6891.0	2160.0
ABHD6	6359.0	7038.0
ABL1	5557.0	-3567.0
ACTN1	-2202.0	6473.0
ACTN2	-160.0	4310.0
ACTN4	2967.0	8423.0
ADRA2A	6239.0	-2148.0
ADRA2B	5948.0	-2943.0
ADRA2C	3959.0	-2881.0
AK3	-3083.0	6676.0
AKAP1	-415.0	2278.0
AKAP10	-5977.0	-1227.0
AKT1	4859.0	7244.0
ALB	6253.0	-380.0
ALDOA	6979.5	3652.5
ANGPT1	-6415.0	8155.0
ANGPT2	3174.0	4727.0
ANGPT4	-4077.0	5377.0
ANXA2	-337.0	8406.0
ANXA5	350.0	5743.0
APBB1IP	-5251.0	-2322.0
APLP2	6384.0	6357.0
APOA1	3682.0	-305.0
APOB	7604.0	5782.0
APOH	-7322.0	1909.0
APOOL	-5900.0	7720.0
APP	-5115.0	6758.0
ARRB1	-6250.0	3030.0
ARRB2	-3644.0	681.0
ATP1B1	8146.0	7502.0
ATP1B2	-1075.0	6478.0
ATP1B3	-1025.0	8436.0
ATP2A1	4773.0	-5655.0
ATP2A2	-7302.0	1164.0
ATP2A3	6309.0	8551.0
ATP2B1	-5922.0	8184.0
ATP2B2	4314.0	-882.0
ATP2B4	7691.0	7255.0
BCAR1	5209.0	-2132.0
BRPF3	6289.0	-4721.0
BSG	-3166.0	5032.0
C1QBP	4206.0	1754.0
CABLES1	5120.0	-5245.0
CABLES2	3168.0	620.0
CALM1	-4401.0	8702.0
CALU	-3535.0	8715.0
CAP1	-1701.0	6877.0
CAPZA1	-6942.0	8474.0
CAPZA2	-1687.0	8135.0
CAPZB	-2513.0	7203.0
CARMIL1	6211.0	2359.0
CAV1	875.0	7970.0
CBX5	-2253.0	4533.0
CD109	-5918.0	1745.0
CD2	-1746.0	-1924.0
CD244	-260.0	-5097.0
CD36	-7328.0	6006.0
CD44	-4381.0	6982.0
CD47	-1991.0	7809.0
CD48	-1928.0	2626.0
CD63	-5955.0	5945.0
CD74	-4460.0	2932.0
CD84	-1375.0	5042.0
CD9	7375.0	4550.0
CD99L2	-6579.0	522.0
CDC37L1	-1999.0	879.0
CDC42	-5961.0	8129.0
CDK2	6186.0	-4240.0
CDK5	2069.0	-2606.0
CEACAM1	3793.5	5357.5
CEACAM3	3793.5	5357.5
CEACAM5	3793.5	5357.5
CEACAM6	3793.5	5357.5
CEACAM8	3793.5	5357.5
CENPE	1973.0	460.0
CFD	6928.0	-5898.0
CFL1	-1720.0	8321.0
CHID1	-5728.0	-4135.0
CLEC1B	-4382.0	2423.0
CLU	7398.0	5822.0
CRK	-3124.0	6926.0
CSK	-5802.0	-2193.0
CTSW	4237.0	-5266.0
CXADR	-7100.0	3254.0
CYB5R1	-603.0	-3666.0
CYRIB	7.0	5059.0
DAGLA	1932.0	-3743.0
DAGLB	-2423.0	-4839.0
DGKA	7789.0	-1905.0
DGKB	-6978.0	1394.0
DGKD	-5580.0	-1130.0
DGKE	3575.0	5098.0
DGKG	-6947.0	-6502.0
DGKH	-4147.0	793.0
DGKI	-2029.0	-5710.0
DGKQ	5815.0	-6572.0
DGKZ	-6561.0	-2123.0
DOCK1	2243.0	382.0
DOCK10	-6602.0	7444.0
DOCK11	-5090.0	5477.0
DOCK2	-5657.0	5085.0
DOCK3	-1237.0	4419.0
DOCK4	-7238.0	7101.0
DOCK5	-5552.0	-1658.0
DOCK6	5969.0	-1935.0
DOCK7	4679.0	-923.0
DOCK8	-7066.0	3808.0
DOCK9	7397.0	723.0
DOK2	3914.0	1693.0
ECM1	3070.0	7327.0
EGF	-4765.0	-210.0
EHD1	-5018.0	2286.0
EHD2	120.0	7054.0
EHD3	-5043.0	8756.0
ENDOD1	-1447.0	6234.0
EPCAM	7886.0	5746.0
ESAM	5409.0	5821.0
F10	7628.0	-1082.0
F11R	2367.0	6083.0
F13A1	3019.0	4962.0
F13B	-4010.0	5799.0
F2	-3087.0	4699.0
F2R	7855.0	8597.0
F2RL2	2932.0	-5992.0
F2RL3	5927.0	-5106.0
F3	3208.0	6573.0
F5	-5716.0	-1378.0
F7	2284.0	-3692.0
F8	-688.0	7499.0
FAM3C	6560.0	8288.0
FCAMR	-7326.0	-1528.0
FCER1G	-3782.0	3932.0
FERMT3	-732.0	3438.0
FGA	4508.0	5893.0
FGB	3640.0	3338.0
FGG	5980.0	5427.0
FGR	-3144.0	378.0
FLNA	-4704.0	7432.0
FN1	7489.0	8379.0
FYN	-2200.0	6221.0
GAS6	7430.0	-2362.0
GATA2	7364.0	-3672.0
GATA3	7885.0	-1653.0
GATA4	-2965.0	622.0
GATA5	3936.0	1362.0
GATA6	-1651.0	6694.0
GLG1	-3103.0	2134.0
GNA11	5503.0	2824.0
GNA12	-6770.0	-3260.0
GNA13	-2710.0	5538.0
GNA14	-6262.0	5551.0
GNA15	-5378.0	2207.0
GNAI1	-6368.0	8547.0
GNAI2	6737.0	5825.0
GNAI3	-3916.0	8277.0
GNAS	-2825.0	5946.0
GNB1	1685.0	7974.0
GNB2	5389.0	-1847.0
GNB4	-4648.0	2711.0
GNB5	4543.0	3032.0
GNG10	5845.0	2921.0
GNG11	-2960.0	5884.0
GNG12	-1212.0	6898.0
GNG2	4011.0	7569.0
GNG3	-1825.0	1443.0
GNG4	-653.0	-591.0
GNG5	-2879.0	-1254.0
GNG7	1904.0	-4062.0
GNG8	499.0	-762.0
GNGT1	1972.0	5695.0
GNGT2	-1053.0	5102.0
GP1BA	7155.0	-6272.0
GP5	578.0	-4171.0
GP6	-4788.0	-1728.0
GP9	-4397.0	3026.0
GPC1	7890.0	581.0
GRB14	6642.0	2356.0
GRB2	3285.0	1922.0
GRB7	-6981.0	-4231.0
GTPBP2	7385.0	-6733.0
GUCY1A2	1000.0	5104.0
GYPA	-4292.0	6256.0
GYPB	-4292.0	6256.0
GYPC	6613.0	-1072.0
H3-3A	-1695.0	7826.0
H3C15	7988.0	2080.0
HABP4	-4981.0	4925.0
HDAC1	-3050.0	4701.0
HDAC2	-6396.0	8620.0
HGF	-6226.0	7929.0
HMG20B	6566.0	-1264.0
HRAS	1503.0	-318.0
HRG	-7287.0	-5709.0
HSPA5	-7309.0	7589.0
IFNA1	1047.0	-1753.0
IFNA10	1047.0	-1753.0
IFNA14	1047.0	-1753.0
IFNA16	1047.0	-1753.0
IFNA17	1047.0	-1753.0
IFNA2	1047.0	-1753.0
IFNA21	1047.0	-1753.0
IFNA4	1047.0	-1753.0
IFNA5	1047.0	-1753.0
IFNA6	1047.0	-1753.0
IFNA7	1047.0	-1753.0
IFNA8	1047.0	-1753.0
IGF1	-6185.0	5101.0
IGF2	-4212.0	5578.0
IGHA1	-5036.5	7384.5
IGHA2	-5036.5	7384.5
IGHM	5659.0	-3544.0
IGHV1-69	-7353.5	8845.5
IGHV2-5	4395.0	4965.0
IGHV2-70	4395.0	4965.0
IGHV7-81	517.5	7570.5
IGKC	-2925.0	7318.0
IGKV1-12	2052.5	4944.5
IGKV1-17	2052.5	4944.5
IGKV1-39	2052.5	4944.5
IGKV1D-12	2052.5	4944.5
IGKV1D-39	2052.5	4944.5
IGKV2-30	101.5	8396.5
IGKV2D-30	101.5	8396.5
IGKV4-1	-7301.0	8840.0
IGKV5-2	-5895.0	8671.0
IGLL1	-968.0	8657.0
IGLV4-60	-3537.5	3617.5
IGLV4-69	-3537.5	3617.5
INPP5D	-1230.0	5535.0
IRAG1	371.0	6869.0
IRF1	3086.0	3498.0
IRF2	542.0	-3491.0
ISLR	2286.0	3772.0
ITGA1	491.0	8564.0
ITGA10	-5938.0	-5542.0
ITGA2	3883.0	2037.0
ITGA2B	4961.0	-4170.0
ITGA3	6960.0	5200.0
ITGA4	-6762.0	7.0
ITGA5	5929.0	6964.0
ITGA6	-6617.0	2201.0
ITGAL	-4315.0	-1137.0
ITGAM	3292.0	5515.0
ITGAV	8155.0	2693.0
ITGAX	-5859.0	2296.0
ITGB1	-6241.0	8758.0
ITGB2	-5238.0	412.0
ITGB3	1530.5	4298.5
ITIH3	1649.0	3397.0
ITIH4	825.0	-82.0
ITPK1	-6865.0	-2177.0
ITPR1	-2727.0	2512.0
ITPR2	4185.0	-2206.0
ITPR3	7844.0	5234.0
JAK2	-2268.0	5565.0
JAM2	-4044.0	6849.0
JAM3	-6751.0	625.0
JCHAIN	-1963.0	6913.0
JMJD1C	-6094.0	5998.0
KCNMA1	7158.0	-4954.0
KCNMB1	2084.0	6965.0
KCNMB3	1191.0	-3830.0
KCNMB4	5674.0	-4284.0
KDM1A	5314.0	-44.0
KIF11	4262.0	-1098.0
KIF12	-3419.0	-6372.0
KIF13B	6407.0	-5191.0
KIF15	91.0	-5193.0
KIF16B	-2844.0	3593.0
KIF18A	-2035.0	4687.0
KIF18B	4824.0	632.0
KIF19	1923.0	-4963.0
KIF1A	5374.0	5302.0
KIF1B	2260.0	5141.0
KIF1C	-812.0	669.0
KIF20A	3022.0	-1094.0
KIF20B	-7215.0	5043.0
KIF21A	-5621.0	7768.0
KIF21B	1267.0	-2504.0
KIF22	-925.0	-1002.0
KIF23	6834.0	-2775.0
KIF26A	3470.0	3765.0
KIF26B	6327.0	-720.0
KIF27	-5722.0	1135.0
KIF2A	1251.0	7652.0
KIF2C	2591.0	-1946.0
KIF3A	-5126.0	3351.0
KIF3B	-3223.0	6725.0
KIF3C	-3455.0	5074.0
KIF4A	1014.0	6024.0
KIF5A	-5260.0	-5278.0
KIF5B	-1547.0	8819.0
KIF5C	6290.0	2117.0
KIF6	5572.0	-4169.0
KIF9	55.0	-2135.0
KIFAP3	41.0	8075.0
KIFC1	8091.0	-6629.0
KIFC2	5216.0	-6709.0
KLC1	143.0	-5336.0
KLC2	6949.0	-4707.0
KLC3	7232.0	-1031.0
KLC4	-6395.0	-2860.0
KLKB1	1003.0	5833.0
KNG1	7980.0	7099.0
KRAS	-752.0	8587.0
L1CAM	7726.0	3102.0
LAMP2	-4970.0	6952.0
LAT	1869.0	-481.0
LCK	-2194.0	5687.0
LCP2	-5980.0	1266.0
LEFTY2	-303.5	5149.5
LGALS3BP	6659.0	-206.0
LHFPL2	-2243.0	2177.0
LRP8	5099.0	707.0
LYN	-4685.0	8216.0
MAFF	4078.0	3523.0
MAFG	-5681.0	-6770.0
MAFK	5915.0	1223.0
MAG	-121.0	-2059.0
MAGED2	5131.0	3251.0
MANF	-7276.0	7166.0
MAPK1	-3928.0	6920.0
MAPK14	-6337.0	-1012.0
MAPK3	5390.0	5167.0
MERTK	2880.0	6387.0
MFN1	417.0	4651.0
MFN2	7230.0	-1391.0
MGLL	8090.0	5435.0
MICAL1	-1713.0	991.0
MIF	8230.0	5317.0
MMRN1	202.0	7918.0
MPL	-4272.0	1987.0
MYB	-5749.0	6744.0
NFE2	4828.0	-3000.0
NHLRC2	929.0	-5359.0
NOS1	6188.0	253.0
NOS2	-1104.0	4079.0
NOS3	1400.0	2054.0
NRAS	3837.0	7903.0
OLA1	-105.0	6435.0
OLR1	-1782.0	2913.0
ORAI1	5373.0	-3312.0
ORAI2	4113.0	4514.0
ORM1	3867.5	-4259.5
ORM2	3867.5	-4259.5
P2RX1	1145.0	5033.0
P2RX2	2031.0	5217.0
P2RX3	1466.0	-4447.0
P2RX4	7060.0	-4339.0
P2RX5	7389.5	1219.5
P2RX6	-1183.0	4957.0
P2RX7	4651.0	4591.0
P2RY1	3518.0	1574.0
P2RY12	1152.0	-4183.0
PAFAH2	-31.0	-3654.0
PCDH7	7022.0	-805.0
PCYOX1L	-6995.0	-5981.0
PDE10A	6281.0	672.0
PDE11A	-6545.0	894.0
PDE1A	-5021.0	5144.0
PDE1B	4499.0	-4026.0
PDE2A	3006.0	4319.0
PDE5A	1433.0	6904.0
PDE9A	5221.0	4762.0
PDGFA	4317.0	4142.0
PDGFB	-990.0	-1987.0
PDPK1	-4074.0	1936.0
PDPN	1062.0	7921.0
PECAM1	3970.0	8677.0
PFN1	-3462.0	-4129.0
PHACTR2	-5595.0	8494.0
PHF21A	-2368.0	829.0
PICK1	5109.0	-6104.0
PIK3CA	-6347.0	2923.0
PIK3CB	-1756.0	1880.0
PIK3CG	-5373.0	8065.0
PIK3R1	-839.0	8363.0
PIK3R2	1669.5	-3969.5
PIK3R3	3779.5	8820.5
PIK3R5	-1994.0	2879.0
PIK3R6	-2176.0	1075.0
PLA2G4A	7058.0	5276.0
PLAT	3772.0	7879.0
PLAU	-5613.0	-5199.0
PLAUR	4004.0	6827.0
PLCG1	8067.0	-4962.0
PLCG2	-5287.0	2474.0
PLEK	-4049.0	7345.0
PLG	1632.0	-1603.0
PPBP	-5336.0	4394.0
PPIA	4868.0	-469.0
PPIL2	-2624.0	2317.0
PPP2CA	-5725.0	8237.0
PPP2CB	5588.0	159.0
PPP2R1A	6355.0	3115.0
PPP2R1B	-6463.0	4855.0
PPP2R5A	7319.0	1089.0
PPP2R5B	627.0	5414.0
PPP2R5C	3181.0	8384.0
PPP2R5D	2088.0	5911.0
PPP2R5E	5001.0	2898.0
PRCP	-6663.0	1095.0
PRKACA	-530.0	15.0
PRKACB	569.0	661.0
PRKAR1A	3942.0	6647.0
PRKAR1B	6901.0	5113.0
PRKAR2A	5319.0	7462.0
PRKAR2B	-2382.0	-990.0
PRKCA	-6271.0	3380.0
PRKCB	-5598.0	5660.0
PRKCD	365.0	1901.0
PRKCE	-5671.0	2371.0
PRKCG	2808.0	-4065.0
PRKCH	-3837.5	7790.5
PRKCQ	-2002.0	-3514.0
PRKCZ	-2030.0	-5814.0
PRKG1	-2535.0	8589.0
PRKG2	1125.0	-4521.0
PROCR	2059.0	3834.0
PROS1	4907.0	7279.0
PSAP	6220.0	-3472.0
PTGIR	-5223.0	4227.0
PTK2	2264.0	6997.0
PTPN1	6946.0	3039.0
PTPN11	-3946.0	6142.0
PTPN6	-1098.0	2140.0
QSOX1	7456.0	1100.0
RAB27B	-4838.0	5533.0
RAB5A	1537.0	7332.0
RAC1	-1258.0	4008.0
RAC2	-3191.0	6081.0
RACGAP1	6146.0	-2445.0
RAD51B	641.0	6559.0
RAD51C	-6645.0	3482.0
RAF1	-6377.0	2465.0
RAP1A	-6787.0	8805.0
RAP1B	942.0	8759.0
RAPGEF3	6998.0	-5986.0
RAPGEF4	-2613.0	5313.0
RARRES2	2602.0	-1260.0
RASGRP1	-370.0	-2734.0
RASGRP2	-326.0	-409.0
RBSN	-6349.0	6778.0
RCOR1	-6714.0	3288.0
RHOA	-5203.0	7671.0
RHOB	5472.0	7262.0
RHOG	2039.0	1654.0
S100A10	7779.0	5985.0
SCCPDH	554.0	-3193.0
SDC1	6076.0	6227.0
SDC2	-6850.0	7623.0
SDC3	5919.0	4486.0
SDC4	6585.0	816.0
SELE	3067.0	6535.0
SELENOP	-7347.0	6139.0
SELL	-4022.0	902.0
SELP	5864.0	2861.0
SELPLG	-5767.0	7976.0
SERPINA1	8234.0	4905.0
SERPINA3	2345.0	8095.0
SERPINB6	7950.0	8360.0
SERPINB8	-5719.0	-5255.0
SERPINC1	-5479.0	2358.0
SERPIND1	-2147.0	-4608.0
SERPINE1	2322.0	8202.0
SERPINE2	6114.0	7966.0
SERPINF2	-6756.0	961.0
SERPING1	3751.0	8403.0
SH2B1	5228.0	-6017.0
SH2B2	-911.0	1569.0
SH2B3	7260.0	-152.0
SHC1	568.0	1962.0
SIN3A	4581.0	6116.0
SIRPA	-6193.5	-6693.5
SIRPG	-6193.5	-6693.5
SLC16A1	-7027.0	5763.0
SLC16A3	5619.0	-3522.0
SLC16A8	87.0	-4934.0
SLC3A2	7436.0	1396.0
SLC7A10	60.0	-1732.0
SLC7A11	-1418.0	-2975.0
SLC7A5	6666.0	-84.0
SLC7A6	4355.0	5198.0
SLC7A7	6551.0	-5468.0
SLC7A8	7330.0	-3995.0
SLC7A9	6467.0	-6401.0
SLC8A1	7391.0	7079.0
SLC8A2	-305.0	-3041.0
SLC8A3	4283.0	1339.0
SOD1	-7054.0	2583.0
SOS1	-6566.0	7698.0
SPARC	6297.0	8700.0
SPN	5031.0	-1295.0
SPP2	4245.0	-2291.0
SRC	-2657.0	-1643.0
SRGN	-1290.0	8312.0
SRI	4336.0	5480.0
STIM1	7832.0	6223.0
STX4	-3184.0	-4491.0
STXBP2	6798.0	725.0
STXBP3	728.0	7644.0
SYK	-6921.0	4480.0
SYTL4	-378.0	-1076.0
TAGLN2	8076.0	4290.0
TBXA2R	-1386.0	741.0
TEK	-2265.0	8575.0
TEX264	1556.0	-5889.0
TF	6988.0	4696.0
TFPI	-5673.0	6729.0
TGFB1	-1851.0	6152.0
TGFB2	4490.0	6652.0
TGFB3	-1546.0	8322.0
THBD	-6500.0	7788.0
THBS1	8000.0	8780.0
THPO	-4688.0	-731.0
TIMP1	-2454.0	3444.0
TIMP3	-7266.0	6800.0
TLN1	-2076.0	-2832.0
TMX3	-6086.0	8558.0
TOR4A	-3960.0	465.0
TP53	2557.0	-3561.0
TREM1	169.0	-2242.0
TRPC3	4682.0	5766.0
TRPC6	-1685.0	1893.0
TSPAN7	4302.5	3267.5
TTN	1028.0	-4101.0
TUBA4A	-5187.0	7242.0
VAV1	-4395.0	5076.0
VAV2	2432.0	-843.0
VAV3	6942.0	5027.0
VCL	-4796.0	7947.0
VEGFA	-4619.0	-5156.0
VEGFB	689.0	-5629.0
VEGFC	-5565.0	-2888.0
VEGFD	7568.0	7674.0
VPREB1	672.0	1924.0
VPS45	-788.0	4784.0
VTI1B	-4642.0	4849.0
VWF	7704.0	-1950.0
WDR1	5440.0	8112.0
WEE1	7395.0	3173.0
YES1	-120.0	7265.0
YWHAZ	-5614.0	8512.0
ZFPM1	7720.0	235.0
ZFPM2	2066.0	4006.0

---

---

Nervous system development

Nervous system development

metric	value
setSize	494
pMANOVA	2.15e-13
p.adjustMANOVA	2.52e-11
s.dist	0.201
s.diabetes	-0.0198
s.mitoG	0.2
p.diabetes	0.453
p.mitoG	3.27e-14

Top 20 genes

Gene	diabetes	mitoG
HSP90AA1	-7286	8742
HSPA8	-7307	8180
PSMC6	-6851	8666
UBB	-7104	8341
PSME4	-6830	8511
PSMD1	-6497	8619
UPF2	-6949	7960
HDAC2	-6396	8620
ITGB1	-6241	8758
GSPT1	-6653	8055
PSMD12	-6149	8628
CUL2	-6236	8506
PSMD7	-6943	7625
RDX	-6580	7989
PSMA1	-6705	7838
ADAM10	-6444	8149
SDC2	-6850	7623
UBC	-6013	8514
NAB1	-5905	8617
PSMC4	-6423	7920

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
ABL1	5557.0	-3567.0
ABL2	-4140.0	5490.0
ABLIM1	-3276.0	6162.0
ABLIM2	6269.0	1264.0
ABLIM3	-2297.0	-2297.0
ACTB	-4152.0	7953.0
ACTG1	-1502.0	1482.0
ACTR2	-5189.0	7356.0
ACTR3	-3716.0	8206.0
ADAM10	-6444.0	8149.0
ADGRG6	2573.0	2838.0
ADGRV1	-4949.0	-6418.0
AGAP2	699.0	1527.0
AGRN	-2966.0	-6131.0
AKAP5	6430.0	224.0
ALCAM	-5367.0	8449.0
ANK1	-2384.0	4523.0
ANK2	6760.0	923.0
ANK3	-300.0	4794.0
AP2A1	3192.0	-2941.0
AP2A2	-6231.0	249.0
AP2B1	-3990.0	7426.0
AP2M1	5073.0	2926.0
AP2S1	587.0	7094.0
APH1A	5635.0	-6359.0
APH1B	7972.0	373.0
ARHGAP35	-2056.0	7180.0
ARHGAP39	-3999.0	-4879.0
ARHGEF11	4676.0	-2477.0
ARHGEF12	-6487.0	5930.0
ARHGEF28	-1889.0	2041.0
ARHGEF7	6228.0	132.0
ARPC1A	-1009.0	-3070.0
ARPC1B	7126.0	2266.0
ARPC2	-4512.0	8767.0
ARPC3	-5747.0	8757.0
ARPC4	3077.0	1525.0
ARPC5	920.0	7514.0
ARTN	115.0	1230.0
CACNA1C	-234.0	-2843.0
CACNA1D	1453.0	-2159.0
CACNA1G	4776.0	-33.0
CACNA1H	2540.0	-2164.0
CACNA1I	-465.0	-462.0
CACNA1S	141.0	7286.0
CACNB1	6319.0	483.0
CACNB2	5838.0	-5134.0
CACNB3	7396.0	5397.0
CACNB4	2205.5	-2030.5
CAP1	-1701.0	6877.0
CAP2	-919.0	1714.0
CASC3	-1205.0	-683.0
CD72	-4839.0	3828.0
CDC42	-5961.0	8129.0
CDK5	2069.0	-2606.0
CDK5R1	4903.0	-6336.0
CFL1	-1720.0	8321.0
CHL1	-6480.0	-3081.0
CLASP1	-1488.0	3748.0
CLASP2	7216.0	4174.0
CLTA	-2807.0	2774.0
CLTB	4559.0	6461.0
CLTC	-4493.0	8248.0
CNTN1	2563.0	-5084.0
CNTN2	-705.0	-3538.0
CNTNAP1	2965.0	-4300.0
COL4A1	-1913.0	7738.0
COL4A2	5885.0	8130.0
COL4A3	-7009.0	2651.0
COL4A4	-7080.0	-2678.0
COL4A5	-1115.0	-5623.0
COL6A1	6555.0	6347.0
COL6A2	6994.0	7492.0
COL6A3	-3162.0	3589.0
COL6A5	-4190.0	6242.0
COL6A6	-7319.0	-1216.0
CREB1	-6809.0	5166.0
CRMP1	-2714.0	2083.0
CSNK2A1	-1453.5	2755.5
CSNK2A2	-2373.0	3684.0
CSNK2B	-3628.0	6622.0
CUL2	-6236.0	8506.0
CXCL12	8169.0	7982.0
CXCR4	4516.0	7547.0
CYP51A1	39.0	-254.0
DAB1	6983.0	261.0
DAG1	6646.0	3480.0
DCX	-2842.0	-4125.0
DLG1	-1980.0	6587.0
DLG3	6540.0	94.0
DLG4	3487.0	-1410.0
DNM1	7171.0	3067.0
DNM2	-1598.0	5364.0
DNM3	6014.0	942.0
DOCK1	2243.0	382.0
DOK1	810.0	4515.0
DOK2	3914.0	1693.0
DOK4	1949.0	-4035.0
DOK5	749.0	1743.0
DOK6	-3399.0	3300.0
DPYSL2	1058.0	7621.0
DPYSL3	-516.0	3651.0
DPYSL4	2689.0	-4514.0
DPYSL5	-3070.0	3557.0
DRP2	917.0	2033.0
DSCAML1	7809.0	-109.0
EFNA1	-1549.0	932.0
EFNA2	1951.0	-1294.0
EFNA3	5736.0	1687.0
EFNA4	137.0	-2379.0
EFNA5	1755.0	2835.0
EFNB1	1192.0	2389.0
EFNB2	-3441.0	7427.0
EFNB3	249.0	-2557.0
EGFR	-6023.0	1902.0
EGR2	-1617.0	4130.0
EIF4A3	2375.0	2229.0
EIF4G1	-5996.0	5731.0
ELOB	6643.0	3269.0
ELOC	-3325.0	7837.0
ENAH	5226.0	20.0
EPHA1	6217.0	-5787.0
EPHA10	-4540.0	6183.0
EPHA2	6325.0	5040.0
EPHA3	882.0	7728.0
EPHA4	2153.0	6163.0
EPHA5	-1398.0	-2714.0
EPHA6	153.0	5349.0
EPHA7	-5493.0	-5429.0
EPHB1	6320.0	3740.0
EPHB2	5434.0	250.0
EPHB3	-1611.0	-932.0
EPHB4	7680.0	5476.0
EPHB6	2138.0	-1906.0
ERBB2	6521.0	-6707.0
ETF1	-3268.0	8174.0
EVL	-186.0	264.0
EZR	5644.0	6288.0
FARP2	-1840.0	78.0
FAU	6809.0	7710.0
FES	-4869.0	2558.0
FGFR1	6753.0	-812.0
FLRT3	-4355.0	5017.0
FRS2	-3456.0	5571.0
FYN	-2200.0	6221.0
GAB1	-4598.0	-3742.0
GAB2	-717.0	7438.0
GDNF	6180.0	-48.0
GFRA1	-5626.0	-3174.0
GFRA2	-4307.0	-618.0
GFRA3	-307.0	-1564.0
GFRA4	6087.0	3762.0
GIT1	5517.0	-142.0
GJB1	-2164.0	2821.0
GPC1	7890.0	581.0
GRB10	-6904.0	2705.0
GRB2	3285.0	1922.0
GRB7	-6981.0	-4231.0
GRIN1	3290.0	-5743.0
GRIN2B	-40.0	2055.0
GSK3B	-5423.0	7184.0
GSPT1	-6653.0	8055.0
GSPT2	-1500.0	-264.0
HDAC2	-6396.0	8620.0
HMGCR	-4034.0	4466.0
HOXA2	1984.0	-3355.0
HRAS	1503.0	-318.0
HSP90AA1	-7286.0	8742.0
HSP90AB1	-7306.0	5626.0
HSPA8	-7307.0	8180.0
IRS2	-582.0	3045.0
ITGA1	491.0	8564.0
ITGA10	-5938.0	-5542.0
ITGA2	3883.0	2037.0
ITGA2B	4961.0	-4170.0
ITGA5	5929.0	6964.0
ITGA9	-6269.0	6974.0
ITGAV	8155.0	2693.0
ITGB1	-6241.0	8758.0
ITGB3	1530.5	4298.5
ITSN1	-2643.0	3175.0
KALRN	8046.0	3199.0
KCNQ2	368.0	-2114.0
KCNQ3	-2961.0	-5979.0
KIF4A	1014.0	6024.0
KRAS	-752.0	8587.0
L1CAM	7726.0	3102.0
LAMA1	5185.0	-6681.0
LAMA2	-764.0	8779.0
LAMB1	1484.0	-2565.0
LAMC1	7625.0	6528.0
LDB1	7924.0	2101.0
LHX4	-3273.0	943.0
LHX9	192.0	3071.0
LIMK1	3519.0	2264.0
LIMK2	7085.0	-848.0
LYN	-4685.0	8216.0
LYPLA2	5438.0	-5928.0
MAG	-121.0	-2059.0
MAGOH	-2387.0	7841.0
MAGOHB	1654.0	1040.0
MAP2K1	7852.0	3274.0
MAP2K2	-2882.5	-4769.5
MAPK1	-3928.0	6920.0
MAPK11	4349.0	2889.0
MAPK12	3182.0	6505.0
MAPK13	8059.0	5735.0
MAPK14	-6337.0	-1012.0
MAPK3	5390.0	5167.0
MAPK7	4710.0	-703.0
MAPK8	-3252.0	1695.0
MBP	6155.0	8284.0
MET	-7325.0	3597.0
MMP2	1375.0	7816.0
MMP9	-5717.0	1502.0
MSI1	7619.0	-2384.0
MSN	-1294.0	5246.0
MYH10	4146.0	675.0
MYH11	4168.0	-24.0
MYH14	7969.0	-5177.0
MYH9	7189.0	7115.0
MYL12B	5155.0	-1502.0
MYL6	241.0	-503.0
MYL9	3189.0	8125.0
MYO10	4745.0	-1478.0
MYO9B	1982.0	-237.0
NAB1	-5905.0	8617.0
NAB2	6580.0	-1542.0
NCAM1	-2962.0	3965.0
NCAN	1112.0	-3927.0
NCBP1	-6452.0	5580.0
NCBP2	-6814.0	136.0
NCK1	-4610.0	8438.0
NCK2	-5808.0	458.0
NCSTN	6534.0	860.0
NELL2	979.0	-3113.0
NEO1	1590.0	-757.0
NFASC	-6650.0	-793.0
NGEF	-5832.0	-4951.0
NRAS	3837.0	7903.0
NRCAM	3619.0	5428.0
NRP1	-6603.0	5497.0
NRP2	849.0	8644.0
NRTN	2219.0	-5311.0
NTN1	-7314.0	-3261.0
NTN4	-2414.0	3491.0
NUMB	-4339.0	4601.0
PABPC1	-949.0	6861.0
PAK1	-886.0	5458.0
PAK2	-4906.0	6708.0
PAK3	2878.0	1881.0
PAK4	-1749.0	-1353.0
PAK6	6221.0	5140.0
PDLIM7	2152.0	6350.0
PFN1	-3462.0	-4129.0
PFN2	701.0	4388.0
PIK3CA	-6347.0	2923.0
PIK3CB	-1756.0	1880.0
PIK3CD	-1968.0	1889.0
PIK3R1	-839.0	8363.0
PIK3R2	1669.5	-3969.5
PIK3R3	3779.5	8820.5
PIP5K1C	6778.0	694.0
PITPNA	-912.0	8721.0
PLCG1	8067.0	-4962.0
PLXNA1	4653.0	-1180.0
PLXNA2	-4201.0	6548.0
PLXNA3	324.0	-181.0
PLXNA4	3459.0	1441.0
PLXNB1	7777.0	-5522.0
PLXNB3	14.0	3666.0
PLXNC1	-5669.0	5576.0
PLXND1	1511.0	4228.0
PMP22	-2901.0	7553.0
POU3F2	3591.0	-2418.0
PPP3CB	-1150.0	4729.0
PRKACA	-530.0	15.0
PRKACB	569.0	661.0
PRKAR2A	5319.0	7462.0
PRKCA	-6271.0	3380.0
PRKCQ	-2002.0	-3514.0
PRNP	8022.0	-3183.0
PRX	5591.0	3972.0
PSEN1	-7020.0	6996.0
PSEN2	-3057.0	-1025.0
PSENEN	-3656.0	5812.0
PSMA1	-6705.0	7838.0
PSMA2	-5464.5	6058.5
PSMA3	-3145.0	7801.0
PSMA4	-6074.0	4688.0
PSMA5	-6660.0	4497.0
PSMA6	-1954.0	8445.0
PSMA7	1612.0	7052.0
PSMA8	649.0	-4004.0
PSMB1	-5281.0	5936.0
PSMB10	3752.0	-908.0
PSMB11	1977.0	-5501.0
PSMB2	1472.0	-4144.0
PSMB3	-3388.0	5539.0
PSMB4	-4941.0	-5852.0
PSMB5	-1638.0	-2409.0
PSMB6	1806.0	-1845.0
PSMB7	-4628.0	-657.0
PSMB8	1080.0	-3793.0
PSMB9	5987.0	-4708.0
PSMC1	-1312.0	4327.0
PSMC2	-6765.0	4648.0
PSMC3	-4285.0	3386.0
PSMC4	-6423.0	7920.0
PSMC5	-4831.0	1120.0
PSMC6	-6851.0	8666.0
PSMD1	-6497.0	8619.0
PSMD10	-1613.0	2576.0
PSMD11	-6873.0	5201.0
PSMD12	-6149.0	8628.0
PSMD13	1898.0	5044.0
PSMD14	-6080.0	8262.0
PSMD2	-6702.0	-3836.0
PSMD3	-2532.0	-3242.0
PSMD4	-5648.0	4994.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
PSMD7	-6943.0	7625.0
PSMD8	1978.0	7546.0
PSMD9	7707.5	-894.5
PSME1	2907.0	5905.0
PSME2	1270.0	-4595.0
PSME3	752.0	7366.0
PSME4	-6830.0	8511.0
PSMF1	5087.0	4771.0
PSPN	-1715.0	-1537.0
PTK2	2264.0	6997.0
PTPN11	-3946.0	6142.0
PTPRA	-5907.0	5079.0
PTPRC	-7112.0	6863.0
RAC1	-1258.0	4008.0
RANBP9	-2687.0	7835.0
RAP1GAP	8071.0	-849.0
RASA1	-5274.0	8011.0
RBM8A	-4975.0	7751.0
RBX1	-391.0	3201.0
RDX	-6580.0	7989.0
RELN	-2728.0	4203.0
RET	-3959.0	186.0
RGMA	2207.0	-1641.0
RGMB	5576.0	106.0
RHOA	-5203.0	7671.0
RHOB	5472.0	7262.0
RHOC	-6806.5	6599.5
RND1	-2800.0	5413.0
RNPS1	5559.0	6960.0
ROBO1	3335.0	7441.0
ROBO2	4411.0	8685.0
ROBO3	-5418.0	-1877.0
ROCK1	-2765.0	8654.0
ROCK2	-1368.0	8738.0
RPL11	5748.0	1403.0
RPL12	6107.0	-5604.0
RPL13	5686.0	-3760.0
RPL14	5110.0	-1875.0
RPL18	2523.0	-625.0
RPL18A	4545.0	-3218.0
RPL19	4654.0	6782.0
RPL21	-1686.0	8463.0
RPL22	2365.0	459.0
RPL22L1	-5123.0	-6294.0
RPL23	-205.0	4253.0
RPL24	-409.0	6813.0
RPL26	3650.0	8722.0
RPL28	6714.0	4753.0
RPL29	2613.0	4628.0
RPL3	5378.0	1155.0
RPL30	4372.0	3664.0
RPL31	6732.0	-1507.0
RPL32	2989.0	8728.0
RPL34	661.0	7140.0
RPL35	5949.0	8834.0
RPL35A	-1509.0	6565.0
RPL36	7543.0	-2424.0
RPL36A	-5983.0	4837.0
RPL36AL	1793.0	-2074.0
RPL37	2109.0	-667.0
RPL38	5601.0	5675.0
RPL3L	-5986.0	4937.0
RPL4	2582.0	8471.0
RPL6	572.0	7594.0
RPL7	-5186.0	8598.0
RPL8	3526.0	820.0
RPLP2	3550.0	3555.0
RPS13	7174.0	315.0
RPS14	4070.0	4443.0
RPS15	7253.0	6174.0
RPS16	6244.0	1119.0
RPS17	5667.0	7685.0
RPS18	4253.0	-526.0
RPS19	6565.0	-1215.0
RPS2	7322.0	4216.0
RPS21	7111.0	-6494.0
RPS25	4261.0	8455.0
RPS27A	-133.0	-1807.0
RPS28	7208.0	-396.0
RPS3	2340.0	4381.0
RPS3A	-3115.0	8824.0
RPS4X	2522.0	7391.0
RPS5	3848.0	7515.0
RPS6	-1700.0	8603.0
RPS6KA1	7703.0	4452.0
RPS6KA2	7237.0	-2956.0
RPS6KA3	-6111.0	8270.0
RPS6KA4	6661.0	-4264.0
RPS6KA5	2516.0	-3206.0
RPS6KA6	-5198.0	2828.0
RPS8	3874.0	7646.0
RPS9	-1719.0	-2555.0
RRAS	5761.0	6583.0
SCN1A	1456.0	-3114.0
SCN1B	6408.0	7111.0
SCN2A	1026.0	1023.0
SCN2B	2199.0	709.0
SCN3A	-2507.0	1492.0
SCN3B	5796.0	-4481.0
SCN4A	3133.0	-3106.0
SCN4B	6329.0	2249.0
SCN5A	6040.0	-3056.0
SCN7A	1493.0	8215.0
SCN8A	3394.0	-3185.0
SDC2	-6850.0	7623.0
SDCBP	5668.0	4540.0
SEMA3A	-748.0	6343.0
SEMA3E	3287.0	6702.0
SEMA4A	4531.0	-6239.0
SEMA4D	-573.0	-5740.0
SEMA5A	-5557.0	182.0
SEMA6A	-6678.0	6683.0
SEMA6D	1160.0	8645.0
SEMA7A	6274.0	6320.0
SH3GL2	-6503.0	867.0
SH3KBP1	3805.0	5866.0
SHANK3	2553.0	-3878.0
SHC1	568.0	1962.0
SHC3	-3555.0	-3601.0
SHTN1	-7073.0	586.0
SIAH1	4474.0	5949.0
SIAH2	1504.0	-2759.0
SLIT1	1701.0	-4596.0
SLIT2	737.0	-1675.0
SLIT3	6674.0	8430.0
SMARCA4	-2170.0	4097.0
SOS1	-6566.0	7698.0
SOS2	-4341.0	7073.0
SPTA1	-2878.0	4811.0
SPTAN1	7051.0	7359.0
SPTB	7834.0	-4096.0
SPTBN1	4136.0	7630.0
SPTBN2	7922.0	-2952.0
SPTBN5	4733.0	-1695.0
SRC	-2657.0	-1643.0
SREBF2	4102.0	-4553.0
SRGAP1	3092.0	5935.0
SRGAP2	-1169.0	-688.0
SRGAP3	6392.0	4176.0
ST8SIA4	-6249.0	6735.0
TEAD1	-7124.0	1943.0
TIAM1	5502.0	5849.0
TLN1	-2076.0	-2832.0
TREM2	-4021.0	2867.0
TRIO	-2249.0	-5133.0
TRPC1	-5396.0	1920.0
TRPC3	4682.0	5766.0
TRPC4	-3076.0	-324.0
TRPC5	555.0	-1490.0
TRPC6	-1685.0	1893.0
TYROBP	-4245.0	2276.0
UBA52	7488.0	-4269.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
UNC5A	-1287.0	-1741.0
UNC5B	6777.0	5303.0
UNC5C	-7233.0	-2826.0
UNC5D	-4908.0	-77.0
UPF2	-6949.0	7960.0
UPF3A	-1867.0	3076.0
UPF3B	3082.0	2946.0
USP33	-7002.0	7120.0
UTRN	5462.0	7245.0
VASP	-2568.0	4503.0
VAV2	2432.0	-843.0
VAV3	6942.0	5027.0
VLDLR	-6562.0	-563.0
WASL	-3989.0	7855.0
WWTR1	4978.0	8485.0
YAP1	-4463.0	1332.0
YES1	-120.0	7265.0
ZSWIM8	6016.0	-3044.0

---

---

Axon guidance

Axon guidance

metric	value
setSize	472
pMANOVA	1.93e-12
p.adjustMANOVA	2.08e-10
s.dist	0.197
s.diabetes	-0.0171
s.mitoG	0.196
p.diabetes	0.525
p.mitoG	3.19e-13

Top 20 genes

Gene	diabetes	mitoG
HSP90AA1	-7286	8742
HSPA8	-7307	8180
PSMC6	-6851	8666
UBB	-7104	8341
PSME4	-6830	8511
PSMD1	-6497	8619
UPF2	-6949	7960
ITGB1	-6241	8758
GSPT1	-6653	8055
PSMD12	-6149	8628
CUL2	-6236	8506
PSMD7	-6943	7625
RDX	-6580	7989
PSMA1	-6705	7838
ADAM10	-6444	8149
SDC2	-6850	7623
UBC	-6013	8514
PSMC4	-6423	7920
SOS1	-6566	7698
RPS6KA3	-6111	8270

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
ABL1	5557.0	-3567.0
ABL2	-4140.0	5490.0
ABLIM1	-3276.0	6162.0
ABLIM2	6269.0	1264.0
ABLIM3	-2297.0	-2297.0
ACTB	-4152.0	7953.0
ACTG1	-1502.0	1482.0
ACTR2	-5189.0	7356.0
ACTR3	-3716.0	8206.0
ADAM10	-6444.0	8149.0
AGAP2	699.0	1527.0
AGRN	-2966.0	-6131.0
AKAP5	6430.0	224.0
ALCAM	-5367.0	8449.0
ANK1	-2384.0	4523.0
ANK2	6760.0	923.0
ANK3	-300.0	4794.0
AP2A1	3192.0	-2941.0
AP2A2	-6231.0	249.0
AP2B1	-3990.0	7426.0
AP2M1	5073.0	2926.0
AP2S1	587.0	7094.0
APH1A	5635.0	-6359.0
APH1B	7972.0	373.0
ARHGAP35	-2056.0	7180.0
ARHGAP39	-3999.0	-4879.0
ARHGEF11	4676.0	-2477.0
ARHGEF12	-6487.0	5930.0
ARHGEF28	-1889.0	2041.0
ARHGEF7	6228.0	132.0
ARPC1A	-1009.0	-3070.0
ARPC1B	7126.0	2266.0
ARPC2	-4512.0	8767.0
ARPC3	-5747.0	8757.0
ARPC4	3077.0	1525.0
ARPC5	920.0	7514.0
ARTN	115.0	1230.0
CACNA1C	-234.0	-2843.0
CACNA1D	1453.0	-2159.0
CACNA1G	4776.0	-33.0
CACNA1H	2540.0	-2164.0
CACNA1I	-465.0	-462.0
CACNA1S	141.0	7286.0
CACNB1	6319.0	483.0
CACNB2	5838.0	-5134.0
CACNB3	7396.0	5397.0
CACNB4	2205.5	-2030.5
CAP1	-1701.0	6877.0
CAP2	-919.0	1714.0
CASC3	-1205.0	-683.0
CD72	-4839.0	3828.0
CDC42	-5961.0	8129.0
CDK5	2069.0	-2606.0
CDK5R1	4903.0	-6336.0
CFL1	-1720.0	8321.0
CHL1	-6480.0	-3081.0
CLASP1	-1488.0	3748.0
CLASP2	7216.0	4174.0
CLTA	-2807.0	2774.0
CLTB	4559.0	6461.0
CLTC	-4493.0	8248.0
CNTN1	2563.0	-5084.0
CNTN2	-705.0	-3538.0
CNTNAP1	2965.0	-4300.0
COL4A1	-1913.0	7738.0
COL4A2	5885.0	8130.0
COL4A3	-7009.0	2651.0
COL4A4	-7080.0	-2678.0
COL4A5	-1115.0	-5623.0
COL6A1	6555.0	6347.0
COL6A2	6994.0	7492.0
COL6A3	-3162.0	3589.0
COL6A5	-4190.0	6242.0
COL6A6	-7319.0	-1216.0
CREB1	-6809.0	5166.0
CRMP1	-2714.0	2083.0
CSNK2A1	-1453.5	2755.5
CSNK2A2	-2373.0	3684.0
CSNK2B	-3628.0	6622.0
CUL2	-6236.0	8506.0
CXCL12	8169.0	7982.0
CXCR4	4516.0	7547.0
DAB1	6983.0	261.0
DAG1	6646.0	3480.0
DCX	-2842.0	-4125.0
DLG1	-1980.0	6587.0
DLG3	6540.0	94.0
DLG4	3487.0	-1410.0
DNM1	7171.0	3067.0
DNM2	-1598.0	5364.0
DNM3	6014.0	942.0
DOCK1	2243.0	382.0
DOK1	810.0	4515.0
DOK2	3914.0	1693.0
DOK4	1949.0	-4035.0
DOK5	749.0	1743.0
DOK6	-3399.0	3300.0
DPYSL2	1058.0	7621.0
DPYSL3	-516.0	3651.0
DPYSL4	2689.0	-4514.0
DPYSL5	-3070.0	3557.0
DSCAML1	7809.0	-109.0
EFNA1	-1549.0	932.0
EFNA2	1951.0	-1294.0
EFNA3	5736.0	1687.0
EFNA4	137.0	-2379.0
EFNA5	1755.0	2835.0
EFNB1	1192.0	2389.0
EFNB2	-3441.0	7427.0
EFNB3	249.0	-2557.0
EGFR	-6023.0	1902.0
EIF4A3	2375.0	2229.0
EIF4G1	-5996.0	5731.0
ELOB	6643.0	3269.0
ELOC	-3325.0	7837.0
ENAH	5226.0	20.0
EPHA1	6217.0	-5787.0
EPHA10	-4540.0	6183.0
EPHA2	6325.0	5040.0
EPHA3	882.0	7728.0
EPHA4	2153.0	6163.0
EPHA5	-1398.0	-2714.0
EPHA6	153.0	5349.0
EPHA7	-5493.0	-5429.0
EPHB1	6320.0	3740.0
EPHB2	5434.0	250.0
EPHB3	-1611.0	-932.0
EPHB4	7680.0	5476.0
EPHB6	2138.0	-1906.0
ERBB2	6521.0	-6707.0
ETF1	-3268.0	8174.0
EVL	-186.0	264.0
EZR	5644.0	6288.0
FARP2	-1840.0	78.0
FAU	6809.0	7710.0
FES	-4869.0	2558.0
FGFR1	6753.0	-812.0
FLRT3	-4355.0	5017.0
FRS2	-3456.0	5571.0
FYN	-2200.0	6221.0
GAB1	-4598.0	-3742.0
GAB2	-717.0	7438.0
GDNF	6180.0	-48.0
GFRA1	-5626.0	-3174.0
GFRA2	-4307.0	-618.0
GFRA3	-307.0	-1564.0
GFRA4	6087.0	3762.0
GIT1	5517.0	-142.0
GPC1	7890.0	581.0
GRB10	-6904.0	2705.0
GRB2	3285.0	1922.0
GRB7	-6981.0	-4231.0
GRIN1	3290.0	-5743.0
GRIN2B	-40.0	2055.0
GSK3B	-5423.0	7184.0
GSPT1	-6653.0	8055.0
GSPT2	-1500.0	-264.0
HOXA2	1984.0	-3355.0
HRAS	1503.0	-318.0
HSP90AA1	-7286.0	8742.0
HSP90AB1	-7306.0	5626.0
HSPA8	-7307.0	8180.0
IRS2	-582.0	3045.0
ITGA1	491.0	8564.0
ITGA10	-5938.0	-5542.0
ITGA2	3883.0	2037.0
ITGA2B	4961.0	-4170.0
ITGA5	5929.0	6964.0
ITGA9	-6269.0	6974.0
ITGAV	8155.0	2693.0
ITGB1	-6241.0	8758.0
ITGB3	1530.5	4298.5
ITSN1	-2643.0	3175.0
KALRN	8046.0	3199.0
KCNQ2	368.0	-2114.0
KCNQ3	-2961.0	-5979.0
KIF4A	1014.0	6024.0
KRAS	-752.0	8587.0
L1CAM	7726.0	3102.0
LAMA1	5185.0	-6681.0
LAMB1	1484.0	-2565.0
LAMC1	7625.0	6528.0
LDB1	7924.0	2101.0
LHX4	-3273.0	943.0
LHX9	192.0	3071.0
LIMK1	3519.0	2264.0
LIMK2	7085.0	-848.0
LYN	-4685.0	8216.0
LYPLA2	5438.0	-5928.0
MAGOH	-2387.0	7841.0
MAGOHB	1654.0	1040.0
MAP2K1	7852.0	3274.0
MAP2K2	-2882.5	-4769.5
MAPK1	-3928.0	6920.0
MAPK11	4349.0	2889.0
MAPK12	3182.0	6505.0
MAPK13	8059.0	5735.0
MAPK14	-6337.0	-1012.0
MAPK3	5390.0	5167.0
MAPK7	4710.0	-703.0
MAPK8	-3252.0	1695.0
MET	-7325.0	3597.0
MMP2	1375.0	7816.0
MMP9	-5717.0	1502.0
MSI1	7619.0	-2384.0
MSN	-1294.0	5246.0
MYH10	4146.0	675.0
MYH11	4168.0	-24.0
MYH14	7969.0	-5177.0
MYH9	7189.0	7115.0
MYL12B	5155.0	-1502.0
MYL6	241.0	-503.0
MYL9	3189.0	8125.0
MYO10	4745.0	-1478.0
MYO9B	1982.0	-237.0
NCAM1	-2962.0	3965.0
NCAN	1112.0	-3927.0
NCBP1	-6452.0	5580.0
NCBP2	-6814.0	136.0
NCK1	-4610.0	8438.0
NCK2	-5808.0	458.0
NCSTN	6534.0	860.0
NELL2	979.0	-3113.0
NEO1	1590.0	-757.0
NFASC	-6650.0	-793.0
NGEF	-5832.0	-4951.0
NRAS	3837.0	7903.0
NRCAM	3619.0	5428.0
NRP1	-6603.0	5497.0
NRP2	849.0	8644.0
NRTN	2219.0	-5311.0
NTN1	-7314.0	-3261.0
NTN4	-2414.0	3491.0
NUMB	-4339.0	4601.0
PABPC1	-949.0	6861.0
PAK1	-886.0	5458.0
PAK2	-4906.0	6708.0
PAK3	2878.0	1881.0
PAK4	-1749.0	-1353.0
PAK6	6221.0	5140.0
PDLIM7	2152.0	6350.0
PFN1	-3462.0	-4129.0
PFN2	701.0	4388.0
PIK3CA	-6347.0	2923.0
PIK3CB	-1756.0	1880.0
PIK3CD	-1968.0	1889.0
PIK3R1	-839.0	8363.0
PIK3R2	1669.5	-3969.5
PIK3R3	3779.5	8820.5
PIP5K1C	6778.0	694.0
PITPNA	-912.0	8721.0
PLCG1	8067.0	-4962.0
PLXNA1	4653.0	-1180.0
PLXNA2	-4201.0	6548.0
PLXNA3	324.0	-181.0
PLXNA4	3459.0	1441.0
PLXNB1	7777.0	-5522.0
PLXNB3	14.0	3666.0
PLXNC1	-5669.0	5576.0
PLXND1	1511.0	4228.0
PPP3CB	-1150.0	4729.0
PRKACA	-530.0	15.0
PRKACB	569.0	661.0
PRKAR2A	5319.0	7462.0
PRKCA	-6271.0	3380.0
PRKCQ	-2002.0	-3514.0
PRNP	8022.0	-3183.0
PSEN1	-7020.0	6996.0
PSEN2	-3057.0	-1025.0
PSENEN	-3656.0	5812.0
PSMA1	-6705.0	7838.0
PSMA2	-5464.5	6058.5
PSMA3	-3145.0	7801.0
PSMA4	-6074.0	4688.0
PSMA5	-6660.0	4497.0
PSMA6	-1954.0	8445.0
PSMA7	1612.0	7052.0
PSMA8	649.0	-4004.0
PSMB1	-5281.0	5936.0
PSMB10	3752.0	-908.0
PSMB11	1977.0	-5501.0
PSMB2	1472.0	-4144.0
PSMB3	-3388.0	5539.0
PSMB4	-4941.0	-5852.0
PSMB5	-1638.0	-2409.0
PSMB6	1806.0	-1845.0
PSMB7	-4628.0	-657.0
PSMB8	1080.0	-3793.0
PSMB9	5987.0	-4708.0
PSMC1	-1312.0	4327.0
PSMC2	-6765.0	4648.0
PSMC3	-4285.0	3386.0
PSMC4	-6423.0	7920.0
PSMC5	-4831.0	1120.0
PSMC6	-6851.0	8666.0
PSMD1	-6497.0	8619.0
PSMD10	-1613.0	2576.0
PSMD11	-6873.0	5201.0
PSMD12	-6149.0	8628.0
PSMD13	1898.0	5044.0
PSMD14	-6080.0	8262.0
PSMD2	-6702.0	-3836.0
PSMD3	-2532.0	-3242.0
PSMD4	-5648.0	4994.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
PSMD7	-6943.0	7625.0
PSMD8	1978.0	7546.0
PSMD9	7707.5	-894.5
PSME1	2907.0	5905.0
PSME2	1270.0	-4595.0
PSME3	752.0	7366.0
PSME4	-6830.0	8511.0
PSMF1	5087.0	4771.0
PSPN	-1715.0	-1537.0
PTK2	2264.0	6997.0
PTPN11	-3946.0	6142.0
PTPRA	-5907.0	5079.0
PTPRC	-7112.0	6863.0
RAC1	-1258.0	4008.0
RANBP9	-2687.0	7835.0
RAP1GAP	8071.0	-849.0
RASA1	-5274.0	8011.0
RBM8A	-4975.0	7751.0
RBX1	-391.0	3201.0
RDX	-6580.0	7989.0
RELN	-2728.0	4203.0
RET	-3959.0	186.0
RGMA	2207.0	-1641.0
RGMB	5576.0	106.0
RHOA	-5203.0	7671.0
RHOB	5472.0	7262.0
RHOC	-6806.5	6599.5
RND1	-2800.0	5413.0
RNPS1	5559.0	6960.0
ROBO1	3335.0	7441.0
ROBO2	4411.0	8685.0
ROBO3	-5418.0	-1877.0
ROCK1	-2765.0	8654.0
ROCK2	-1368.0	8738.0
RPL11	5748.0	1403.0
RPL12	6107.0	-5604.0
RPL13	5686.0	-3760.0
RPL14	5110.0	-1875.0
RPL18	2523.0	-625.0
RPL18A	4545.0	-3218.0
RPL19	4654.0	6782.0
RPL21	-1686.0	8463.0
RPL22	2365.0	459.0
RPL22L1	-5123.0	-6294.0
RPL23	-205.0	4253.0
RPL24	-409.0	6813.0
RPL26	3650.0	8722.0
RPL28	6714.0	4753.0
RPL29	2613.0	4628.0
RPL3	5378.0	1155.0
RPL30	4372.0	3664.0
RPL31	6732.0	-1507.0
RPL32	2989.0	8728.0
RPL34	661.0	7140.0
RPL35	5949.0	8834.0
RPL35A	-1509.0	6565.0
RPL36	7543.0	-2424.0
RPL36A	-5983.0	4837.0
RPL36AL	1793.0	-2074.0
RPL37	2109.0	-667.0
RPL38	5601.0	5675.0
RPL3L	-5986.0	4937.0
RPL4	2582.0	8471.0
RPL6	572.0	7594.0
RPL7	-5186.0	8598.0
RPL8	3526.0	820.0
RPLP2	3550.0	3555.0
RPS13	7174.0	315.0
RPS14	4070.0	4443.0
RPS15	7253.0	6174.0
RPS16	6244.0	1119.0
RPS17	5667.0	7685.0
RPS18	4253.0	-526.0
RPS19	6565.0	-1215.0
RPS2	7322.0	4216.0
RPS21	7111.0	-6494.0
RPS25	4261.0	8455.0
RPS27A	-133.0	-1807.0
RPS28	7208.0	-396.0
RPS3	2340.0	4381.0
RPS3A	-3115.0	8824.0
RPS4X	2522.0	7391.0
RPS5	3848.0	7515.0
RPS6	-1700.0	8603.0
RPS6KA1	7703.0	4452.0
RPS6KA2	7237.0	-2956.0
RPS6KA3	-6111.0	8270.0
RPS6KA4	6661.0	-4264.0
RPS6KA5	2516.0	-3206.0
RPS6KA6	-5198.0	2828.0
RPS8	3874.0	7646.0
RPS9	-1719.0	-2555.0
RRAS	5761.0	6583.0
SCN1A	1456.0	-3114.0
SCN1B	6408.0	7111.0
SCN2A	1026.0	1023.0
SCN2B	2199.0	709.0
SCN3A	-2507.0	1492.0
SCN3B	5796.0	-4481.0
SCN4A	3133.0	-3106.0
SCN4B	6329.0	2249.0
SCN5A	6040.0	-3056.0
SCN7A	1493.0	8215.0
SCN8A	3394.0	-3185.0
SDC2	-6850.0	7623.0
SDCBP	5668.0	4540.0
SEMA3A	-748.0	6343.0
SEMA3E	3287.0	6702.0
SEMA4A	4531.0	-6239.0
SEMA4D	-573.0	-5740.0
SEMA5A	-5557.0	182.0
SEMA6A	-6678.0	6683.0
SEMA6D	1160.0	8645.0
SEMA7A	6274.0	6320.0
SH3GL2	-6503.0	867.0
SH3KBP1	3805.0	5866.0
SHANK3	2553.0	-3878.0
SHC1	568.0	1962.0
SHC3	-3555.0	-3601.0
SHTN1	-7073.0	586.0
SIAH1	4474.0	5949.0
SIAH2	1504.0	-2759.0
SLIT1	1701.0	-4596.0
SLIT2	737.0	-1675.0
SLIT3	6674.0	8430.0
SOS1	-6566.0	7698.0
SOS2	-4341.0	7073.0
SPTA1	-2878.0	4811.0
SPTAN1	7051.0	7359.0
SPTB	7834.0	-4096.0
SPTBN1	4136.0	7630.0
SPTBN2	7922.0	-2952.0
SPTBN5	4733.0	-1695.0
SRC	-2657.0	-1643.0
SRGAP1	3092.0	5935.0
SRGAP2	-1169.0	-688.0
SRGAP3	6392.0	4176.0
ST8SIA4	-6249.0	6735.0
TIAM1	5502.0	5849.0
TLN1	-2076.0	-2832.0
TREM2	-4021.0	2867.0
TRIO	-2249.0	-5133.0
TRPC1	-5396.0	1920.0
TRPC3	4682.0	5766.0
TRPC4	-3076.0	-324.0
TRPC5	555.0	-1490.0
TRPC6	-1685.0	1893.0
TYROBP	-4245.0	2276.0
UBA52	7488.0	-4269.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
UNC5A	-1287.0	-1741.0
UNC5B	6777.0	5303.0
UNC5C	-7233.0	-2826.0
UNC5D	-4908.0	-77.0
UPF2	-6949.0	7960.0
UPF3A	-1867.0	3076.0
UPF3B	3082.0	2946.0
USP33	-7002.0	7120.0
VASP	-2568.0	4503.0
VAV2	2432.0	-843.0
VAV3	6942.0	5027.0
VLDLR	-6562.0	-563.0
WASL	-3989.0	7855.0
YES1	-120.0	7265.0
ZSWIM8	6016.0	-3044.0

---

---

Developmental Biology

Developmental Biology

metric	value
setSize	770
pMANOVA	5.3e-12
p.adjustMANOVA	5.2e-10
s.dist	0.146
s.diabetes	0.0198
s.mitoG	0.145
p.diabetes	0.352
p.mitoG	1.16e-11

Top 20 genes

Gene	diabetes	mitoG
CXCL12	8169	7982
FABP4	7019	8615
EPAS1	6886	8502
SLIT3	6674	8430
KRT18	7629	6979
RPL35	5949	8834
FAU	6809	7710
COL6A2	6994	7492
DSP	7655	6828
SPTAN1	7051	7359
MYH9	7189	7115
MBP	6155	8284
LAMC1	7625	6528
CDKN1A	7594	6372
COL4A2	5885	8130
KRT19	5825	8106
MAPK13	8059	5735
SCN1B	6408	7111
RPS15	7253	6174
RPS17	5667	7685

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
ABL1	5557.0	-3567.0
ABL2	-4140.0	5490.0
ABLIM1	-3276.0	6162.0
ABLIM2	6269.0	1264.0
ABLIM3	-2297.0	-2297.0
ACTB	-4152.0	7953.0
ACTG1	-1502.0	1482.0
ACTR2	-5189.0	7356.0
ACTR3	-3716.0	8206.0
ACVR1B	8114.0	-3646.0
ACVR1C	332.0	-4753.0
ACVR2A	-2908.0	8211.0
ACVR2B	4439.0	-6603.0
ADAM10	-6444.0	8149.0
ADAM11	5988.0	-3863.0
ADAM22	6381.0	6795.0
ADAM23	-1374.0	-2704.0
ADGRG6	2573.0	2838.0
ADGRV1	-4949.0	-6418.0
ADIPOQ	3018.0	-3550.0
AGAP2	699.0	1527.0
AGRN	-2966.0	-6131.0
AJUBA	-194.0	-1290.0
AKAP5	6430.0	224.0
AKT1	4859.0	7244.0
AKT2	-4939.0	3281.0
AKT3	-375.0	7862.0
ALCAM	-5367.0	8449.0
ANGPTL4	1374.0	2720.0
ANK1	-2384.0	4523.0
ANK2	6760.0	923.0
ANK3	-300.0	4794.0
AP2A1	3192.0	-2941.0
AP2A2	-6231.0	249.0
AP2B1	-3990.0	7426.0
AP2M1	5073.0	2926.0
AP2S1	587.0	7094.0
APH1A	5635.0	-6359.0
APH1B	7972.0	373.0
ARHGAP35	-2056.0	7180.0
ARHGAP39	-3999.0	-4879.0
ARHGEF11	4676.0	-2477.0
ARHGEF12	-6487.0	5930.0
ARHGEF28	-1889.0	2041.0
ARHGEF7	6228.0	132.0
ARPC1A	-1009.0	-3070.0
ARPC1B	7126.0	2266.0
ARPC2	-4512.0	8767.0
ARPC3	-5747.0	8757.0
ARPC4	3077.0	1525.0
ARPC5	920.0	7514.0
ARTN	115.0	1230.0
ASH2L	573.0	2942.0
BNIP2	3400.0	6267.0
BOC	4361.0	6773.0
CACNA1C	-234.0	-2843.0
CACNA1D	1453.0	-2159.0
CACNA1G	4776.0	-33.0
CACNA1H	2540.0	-2164.0
CACNA1I	-465.0	-462.0
CACNA1S	141.0	7286.0
CACNB1	6319.0	483.0
CACNB2	5838.0	-5134.0
CACNB3	7396.0	5397.0
CACNB4	2205.5	-2030.5
CACNG2	3385.0	-6063.0
CACNG4	-3655.0	-4722.0
CAP1	-1701.0	6877.0
CAP2	-919.0	1714.0
CAPN1	7308.0	-2267.0
CAPNS1	1113.0	6245.0
CARM1	4760.0	-3487.0
CASC3	-1205.0	-683.0
CBFB	-4270.0	8061.0
CCNC	-3288.0	7605.0
CCND3	6126.0	-3725.0
CD36	-7328.0	6006.0
CD72	-4839.0	3828.0
CDC42	-5961.0	8129.0
CDH2	-7013.0	-2104.0
CDH4	5542.0	1367.0
CDK19	5061.0	2530.0
CDK2	6186.0	-4240.0
CDK4	3355.0	-1971.0
CDK5	2069.0	-2606.0
CDK5R1	4903.0	-6336.0
CDK8	5984.0	-5196.0
CDKN1A	7594.0	6372.0
CDON	-5264.0	357.0
CDSN	2550.0	-3325.0
CEBPA	3214.0	-5419.0
CEBPB	7403.0	754.0
CEBPD	3288.0	6984.0
CELA2A	3787.5	-5197.5
CER1	-424.0	897.0
CFL1	-1720.0	8321.0
CHD9	-6925.0	8050.0
CHL1	-6480.0	-3081.0
CLASP1	-1488.0	3748.0
CLASP2	7216.0	4174.0
CLTA	-2807.0	2774.0
CLTB	4559.0	6461.0
CLTC	-4493.0	8248.0
CNOT6	-5929.0	7904.0
CNTN1	2563.0	-5084.0
CNTN2	-705.0	-3538.0
CNTNAP1	2965.0	-4300.0
COL4A1	-1913.0	7738.0
COL4A2	5885.0	8130.0
COL4A3	-7009.0	2651.0
COL4A4	-7080.0	-2678.0
COL4A5	-1115.0	-5623.0
COL6A1	6555.0	6347.0
COL6A2	6994.0	7492.0
COL6A3	-3162.0	3589.0
COL6A5	-4190.0	6242.0
COL6A6	-7319.0	-1216.0
CREB1	-6809.0	5166.0
CREBBP	-6181.0	3954.0
CRMP1	-2714.0	2083.0
CSF3R	-5607.0	5881.0
CSNK2A1	-1453.5	2755.5
CSNK2A2	-2373.0	3684.0
CSNK2B	-3628.0	6622.0
CSTA	-448.0	-6486.0
CTCF	-4945.0	7814.0
CTNNA1	2129.0	7795.0
CTNNA2	-3877.0	-2541.0
CTNNB1	-6022.0	2664.0
CUL2	-6236.0	8506.0
CXCL12	8169.0	7982.0
CXCR4	4516.0	7547.0
CYP51A1	39.0	-254.0
DAB1	6983.0	261.0
DAG1	6646.0	3480.0
DAND5	-41.0	2242.0
DCX	-2842.0	-4125.0
DEK	3449.0	8817.0
DKK1	2430.0	-4371.0
DLG1	-1980.0	6587.0
DLG3	6540.0	94.0
DLG4	3487.0	-1410.0
DNM1	7171.0	3067.0
DNM2	-1598.0	5364.0
DNM3	6014.0	942.0
DOCK1	2243.0	382.0
DOK1	810.0	4515.0
DOK2	3914.0	1693.0
DOK4	1949.0	-4035.0
DOK5	749.0	1743.0
DOK6	-3399.0	3300.0
DPYSL2	1058.0	7621.0
DPYSL3	-516.0	3651.0
DPYSL4	2689.0	-4514.0
DPYSL5	-3070.0	3557.0
DRAP1	5968.0	6776.0
DRP2	917.0	2033.0
DSC2	790.0	-85.0
DSCAML1	7809.0	-109.0
DSG2	7918.0	5394.0
DSP	7655.0	6828.0
E2F1	4935.0	-488.0
EBF1	-3641.0	6536.0
EED	-1977.0	6430.0
EFNA1	-1549.0	932.0
EFNA2	1951.0	-1294.0
EFNA3	5736.0	1687.0
EFNA4	137.0	-2379.0
EFNA5	1755.0	2835.0
EFNB1	1192.0	2389.0
EFNB2	-3441.0	7427.0
EFNB3	249.0	-2557.0
EGFR	-6023.0	1902.0
EGR2	-1617.0	4130.0
EIF4A3	2375.0	2229.0
EIF4G1	-5996.0	5731.0
ELOB	6643.0	3269.0
ELOC	-3325.0	7837.0
ENAH	5226.0	20.0
EOMES	-3851.0	1233.0
EP300	-2449.0	1336.0
EPAS1	6886.0	8502.0
EPHA1	6217.0	-5787.0
EPHA10	-4540.0	6183.0
EPHA2	6325.0	5040.0
EPHA3	882.0	7728.0
EPHA4	2153.0	6163.0
EPHA5	-1398.0	-2714.0
EPHA6	153.0	5349.0
EPHA7	-5493.0	-5429.0
EPHB1	6320.0	3740.0
EPHB2	5434.0	250.0
EPHB3	-1611.0	-932.0
EPHB4	7680.0	5476.0
EPHB6	2138.0	-1906.0
ERBB2	6521.0	-6707.0
ETF1	-3268.0	8174.0
EVL	-186.0	264.0
EVPL	7290.0	-6189.0
EZH2	13.0	1789.0
EZR	5644.0	6288.0
FABP4	7019.0	8615.0
FAM120B	-5510.0	-1760.0
FARP2	-1840.0	78.0
FAU	6809.0	7710.0
FES	-4869.0	2558.0
FGF10	-2375.0	-1761.0
FGF2	792.0	3696.0
FGFR1	6753.0	-812.0
FLG	8123.0	-6549.0
FLI1	-110.0	7996.0
FLRT3	-4355.0	5017.0
FOXA3	6771.0	-2393.0
FOXO1	6562.0	90.0
FOXO3	7446.0	393.0
FRS2	-3456.0	5571.0
FURIN	3696.0	-3590.0
FYN	-2200.0	6221.0
GAB1	-4598.0	-3742.0
GAB2	-717.0	7438.0
GATA2	7364.0	-3672.0
GATA6	-1651.0	6694.0
GDF1	-393.5	-2230.5
GDNF	6180.0	-48.0
GFI1	-1521.0	3358.0
GFRA1	-5626.0	-3174.0
GFRA2	-4307.0	-618.0
GFRA3	-307.0	-1564.0
GFRA4	6087.0	3762.0
GIT1	5517.0	-142.0
GJB1	-2164.0	2821.0
GPC1	7890.0	581.0
GRB10	-6904.0	2705.0
GRB2	3285.0	1922.0
GRB7	-6981.0	-4231.0
GRIN1	3290.0	-5743.0
GRIN2B	-40.0	2055.0
GSK3B	-5423.0	7184.0
GSPT1	-6653.0	8055.0
GSPT2	-1500.0	-264.0
H2AC20	7413.0	2470.0
H2AJ	-5416.0	2537.0
H2AZ1	-980.0	4206.0
H2AZ2	3558.0	1431.0
H2BC11	3900.0	-3127.0
H2BC14	1703.0	1613.0
H2BC5	3445.0	-761.0
H3-3A	-1695.0	7826.0
H3C15	7988.0	2080.0
HDAC2	-6396.0	8620.0
HDAC3	5142.0	-772.0
HELZ2	1736.0	2464.0
HES1	7353.0	4261.0
HIF3A	5098.0	-246.0
HMGCR	-4034.0	4466.0
HNF1A	7450.0	-6675.0
HNF1B	-1771.0	-6141.0
HNF4A	-6855.0	4619.0
HNF4G	-6407.0	-1223.0
HOXA1	2324.0	-4912.0
HOXA2	1984.0	-3355.0
HOXA3	2023.0	-6430.0
HOXA4	3436.0	-2316.0
HOXB1	-3171.0	308.0
HOXB2	3797.0	-3215.0
HOXB3	5631.0	-6102.0
HOXB4	-3323.0	-6276.0
HOXC4	4837.0	-4459.0
HOXD3	6803.0	-2112.0
HOXD4	-6066.0	-6767.0
HRAS	1503.0	-318.0
HSP90AA1	-7286.0	8742.0
HSP90AB1	-7306.0	5626.0
HSPA8	-7307.0	8180.0
IL6R	-730.0	6215.0
IRS2	-582.0	3045.0
ITGA1	491.0	8564.0
ITGA10	-5938.0	-5542.0
ITGA2	3883.0	2037.0
ITGA2B	4961.0	-4170.0
ITGA5	5929.0	6964.0
ITGA9	-6269.0	6974.0
ITGAV	8155.0	2693.0
ITGB1	-6241.0	8758.0
ITGB3	1530.5	4298.5
ITSN1	-2643.0	3175.0
JUN	581.0	5314.0
JUP	4751.0	2870.0
KALRN	8046.0	3199.0
KAT2A	-3442.0	-2675.0
KAT2B	-5780.0	6796.0
KAZN	8029.0	-6560.0
KCNQ2	368.0	-2114.0
KCNQ3	-2961.0	-5979.0
KDM6A	-490.0	3226.0
KIF4A	1014.0	6024.0
KLF4	5830.0	7414.0
KLF5	590.0	2443.0
KLK8	991.0	2858.0
KMT2A	-1536.5	-3090.5
KMT2C	-6795.0	7375.0
KMT2D	-2043.0	-6534.0
KRAS	-752.0	8587.0
KRT10	-4103.0	6321.0
KRT15	747.0	-1021.0
KRT18	7629.0	6979.0
KRT19	5825.0	8106.0
KRT20	5828.0	-3753.0
KRT23	-660.0	3043.0
KRT25	3271.0	-4871.0
KRT26	3111.0	-5186.0
KRT35	-3833.0	-2204.0
KRT5	932.0	-3906.0
KRT7	7533.0	5052.0
KRT8	7541.0	204.0
KRT80	2874.0	-782.0
L1CAM	7726.0	3102.0
LAMA1	5185.0	-6681.0
LAMA2	-764.0	8779.0
LAMB1	1484.0	-2565.0
LAMC1	7625.0	6528.0
LDB1	7924.0	2101.0
LEF1	-2640.0	6342.0
LEFTY1	-303.5	5149.5
LEFTY2	-303.5	5149.5
LGI1	-4360.0	-115.0
LGI2	3789.0	1353.0
LGI3	3083.0	207.0
LGI4	390.0	-241.0
LHX4	-3273.0	943.0
LHX9	192.0	3071.0
LIMK1	3519.0	2264.0
LIMK2	7085.0	-848.0
LPL	-7356.0	1308.0
LYN	-4685.0	8216.0
LYPLA2	5438.0	-5928.0
MAFA	-3053.0	2846.0
MAFB	8140.0	2473.0
MAG	-121.0	-2059.0
MAGOH	-2387.0	7841.0
MAGOHB	1654.0	1040.0
MAML1	4934.0	2236.0
MAML2	7613.0	4513.0
MAML3	7180.0	5765.0
MAMLD1	6705.0	2789.0
MAP2K1	7852.0	3274.0
MAP2K2	-2882.5	-4769.5
MAP2K6	5640.0	-4115.0
MAPK1	-3928.0	6920.0
MAPK11	4349.0	2889.0
MAPK12	3182.0	6505.0
MAPK13	8059.0	5735.0
MAPK14	-6337.0	-1012.0
MAPK3	5390.0	5167.0
MAPK7	4710.0	-703.0
MAPK8	-3252.0	1695.0
MBP	6155.0	8284.0
MED1	-6294.0	6202.0
MED10	-216.0	6866.0
MED11	4114.0	-2523.0
MED12	2883.0	-4523.0
MED13	-6622.0	7554.0
MED13L	-1854.0	2715.0
MED14	-7065.0	3403.0
MED15	4680.0	-4482.0
MED16	7676.0	-3167.0
MED17	-3014.5	1170.5
MED18	-5417.0	3852.0
MED19	-3593.0	7428.0
MED20	2722.0	-6368.0
MED21	-6615.0	7431.0
MED22	6145.0	-4961.0
MED23	-5988.0	936.0
MED24	-491.0	-1343.0
MED25	5022.0	-6109.0
MED26	6356.5	-2626.5
MED27	1369.0	-4165.0
MED28	-6976.0	-959.0
MED29	-3922.0	157.0
MED30	6587.0	-3243.0
MED31	3971.0	1460.0
MED4	-102.0	4608.0
MED6	-95.0	5484.0
MED7	-2359.0	7513.0
MED8	-1103.0	4114.0
MED9	4897.0	-1301.0
MEF2A	-2071.0	7495.0
MEF2C	-1905.0	8451.0
MEF2D	3560.0	-675.0
MEIS1	840.0	-3731.0
MET	-7325.0	3597.0
MMP2	1375.0	7816.0
MMP9	-5717.0	1502.0
MSI1	7619.0	-2384.0
MSN	-1294.0	5246.0
MYB	-5749.0	6744.0
MYC	1892.0	3123.0
MYH10	4146.0	675.0
MYH11	4168.0	-24.0
MYH14	7969.0	-5177.0
MYH9	7189.0	7115.0
MYL12B	5155.0	-1502.0
MYL6	241.0	-503.0
MYL9	3189.0	8125.0
MYO10	4745.0	-1478.0
MYO9B	1982.0	-237.0
NAB1	-5905.0	8617.0
NAB2	6580.0	-1542.0
NANOG	-2036.5	-2968.5
NCAM1	-2962.0	3965.0
NCAN	1112.0	-3927.0
NCBP1	-6452.0	5580.0
NCBP2	-6814.0	136.0
NCK1	-4610.0	8438.0
NCK2	-5808.0	458.0
NCOA1	-3434.0	7005.0
NCOA2	-5757.0	5994.0
NCOA3	-4267.0	2629.0
NCOA6	-4607.0	8043.0
NCOR1	-7262.0	6244.0
NCOR2	-225.0	-3484.0
NCSTN	6534.0	860.0
NELL2	979.0	-3113.0
NEO1	1590.0	-757.0
NFASC	-6650.0	-793.0
NFKB1	5449.0	4035.0
NGEF	-5832.0	-4951.0
NKX6-1	1836.0	-2277.0
NOTCH1	5759.0	5529.0
NR2F2	-3613.0	4417.0
NR5A2	-2631.0	-1601.0
NR6A1	4201.0	-3199.0
NRAS	3837.0	7903.0
NRCAM	3619.0	5428.0
NRP1	-6603.0	5497.0
NRP2	849.0	8644.0
NRTN	2219.0	-5311.0
NTN1	-7314.0	-3261.0
NTN3	1943.0	-378.0
NTN4	-2414.0	3491.0
NUMB	-4339.0	4601.0
ONECUT3	-328.0	-5812.0
PABPC1	-949.0	6861.0
PAGR1	-1690.0	-857.0
PAK1	-886.0	5458.0
PAK2	-4906.0	6708.0
PAK3	2878.0	1881.0
PAK4	-1749.0	-1353.0
PAK6	6221.0	5140.0
PAX6	-2974.0	1272.0
PAXIP1	7685.0	-4472.0
PBX1	-1586.0	7773.0
PCGF2	6981.0	-1609.0
PCK1	6911.0	5688.0
PCSK6	6074.0	24.0
PDLIM7	2152.0	6350.0
PERP	-5917.0	6293.0
PFN1	-3462.0	-4129.0
PFN2	701.0	4388.0
PIAS2	-551.0	4275.0
PIK3CA	-6347.0	2923.0
PIK3CB	-1756.0	1880.0
PIK3CD	-1968.0	1889.0
PIK3R1	-839.0	8363.0
PIK3R2	1669.5	-3969.5
PIK3R3	3779.5	8820.5
PIP5K1C	6778.0	694.0
PITPNA	-912.0	8721.0
PKLR	8195.0	-127.0
PKNOX1	-7234.0	4054.0
PKP2	3943.0	4710.0
PKP3	128.0	-2574.0
PKP4	-3865.0	5106.0
PLCG1	8067.0	-4962.0
PLIN1	-3309.0	-4723.0
PLXNA1	4653.0	-1180.0
PLXNA2	-4201.0	6548.0
PLXNA3	324.0	-181.0
PLXNA4	3459.0	1441.0
PLXNB1	7777.0	-5522.0
PLXNB3	14.0	3666.0
PLXNC1	-5669.0	5576.0
PLXND1	1511.0	4228.0
PML	6152.0	-5597.0
PMP22	-2901.0	7553.0
POLR2A	4937.0	-1941.0
POLR2B	-675.0	5037.0
POLR2C	2928.0	6859.0
POLR2D	-2762.0	6076.0
POLR2E	7128.0	-3504.0
POLR2F	6184.0	-3058.0
POLR2G	3306.0	-3566.0
POLR2H	4359.0	-4161.0
POLR2I	5890.0	6864.0
POLR2J	1742.0	3424.0
POLR2K	1098.0	7632.0
POLR2L	3697.0	-3808.0
POU3F2	3591.0	-2418.0
PPARA	7841.0	-6419.0
PPARG	-3636.0	5654.0
PPARGC1A	7867.0	2494.0
PPL	7566.0	183.0
PPP3CB	-1150.0	4729.0
PRKACA	-530.0	15.0
PRKACB	569.0	661.0
PRKAR2A	5319.0	7462.0
PRKCA	-6271.0	3380.0
PRKCQ	-2002.0	-3514.0
PRNP	8022.0	-3183.0
PRSS8	2016.0	-6275.0
PRX	5591.0	3972.0
PSEN1	-7020.0	6996.0
PSEN2	-3057.0	-1025.0
PSENEN	-3656.0	5812.0
PSMA1	-6705.0	7838.0
PSMA2	-5464.5	6058.5
PSMA3	-3145.0	7801.0
PSMA4	-6074.0	4688.0
PSMA5	-6660.0	4497.0
PSMA6	-1954.0	8445.0
PSMA7	1612.0	7052.0
PSMA8	649.0	-4004.0
PSMB1	-5281.0	5936.0
PSMB10	3752.0	-908.0
PSMB11	1977.0	-5501.0
PSMB2	1472.0	-4144.0
PSMB3	-3388.0	5539.0
PSMB4	-4941.0	-5852.0
PSMB5	-1638.0	-2409.0
PSMB6	1806.0	-1845.0
PSMB7	-4628.0	-657.0
PSMB8	1080.0	-3793.0
PSMB9	5987.0	-4708.0
PSMC1	-1312.0	4327.0
PSMC2	-6765.0	4648.0
PSMC3	-4285.0	3386.0
PSMC4	-6423.0	7920.0
PSMC5	-4831.0	1120.0
PSMC6	-6851.0	8666.0
PSMD1	-6497.0	8619.0
PSMD10	-1613.0	2576.0
PSMD11	-6873.0	5201.0
PSMD12	-6149.0	8628.0
PSMD13	1898.0	5044.0
PSMD14	-6080.0	8262.0
PSMD2	-6702.0	-3836.0
PSMD3	-2532.0	-3242.0
PSMD4	-5648.0	4994.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
PSMD7	-6943.0	7625.0
PSMD8	1978.0	7546.0
PSMD9	7707.5	-894.5
PSME1	2907.0	5905.0
PSME2	1270.0	-4595.0
PSME3	752.0	7366.0
PSME4	-6830.0	8511.0
PSMF1	5087.0	4771.0
PSPN	-1715.0	-1537.0
PTK2	2264.0	6997.0
PTPN11	-3946.0	6142.0
PTPRA	-5907.0	5079.0
PTPRC	-7112.0	6863.0
RAC1	-1258.0	4008.0
RANBP9	-2687.0	7835.0
RAP1GAP	8071.0	-849.0
RARA	183.0	-5463.0
RARB	1095.0	6818.0
RARG	1812.0	95.0
RASA1	-5274.0	8011.0
RBBP4	-6148.0	5835.0
RBBP5	-4912.0	-38.0
RBBP7	2154.0	6750.0
RBM8A	-4975.0	7751.0
RBPJ	2571.0	4528.0
RBX1	-391.0	3201.0
RDX	-6580.0	7989.0
RELA	2579.0	-2368.0
RELN	-2728.0	4203.0
RET	-3959.0	186.0
RGMA	2207.0	-1641.0
RGMB	5576.0	106.0
RHOA	-5203.0	7671.0
RHOB	5472.0	7262.0
RHOC	-6806.5	6599.5
RND1	-2800.0	5413.0
RNPS1	5559.0	6960.0
ROBO1	3335.0	7441.0
ROBO2	4411.0	8685.0
ROBO3	-5418.0	-1877.0
ROCK1	-2765.0	8654.0
ROCK2	-1368.0	8738.0
RPL11	5748.0	1403.0
RPL12	6107.0	-5604.0
RPL13	5686.0	-3760.0
RPL14	5110.0	-1875.0
RPL18	2523.0	-625.0
RPL18A	4545.0	-3218.0
RPL19	4654.0	6782.0
RPL21	-1686.0	8463.0
RPL22	2365.0	459.0
RPL22L1	-5123.0	-6294.0
RPL23	-205.0	4253.0
RPL24	-409.0	6813.0
RPL26	3650.0	8722.0
RPL28	6714.0	4753.0
RPL29	2613.0	4628.0
RPL3	5378.0	1155.0
RPL30	4372.0	3664.0
RPL31	6732.0	-1507.0
RPL32	2989.0	8728.0
RPL34	661.0	7140.0
RPL35	5949.0	8834.0
RPL35A	-1509.0	6565.0
RPL36	7543.0	-2424.0
RPL36A	-5983.0	4837.0
RPL36AL	1793.0	-2074.0
RPL37	2109.0	-667.0
RPL38	5601.0	5675.0
RPL3L	-5986.0	4937.0
RPL4	2582.0	8471.0
RPL6	572.0	7594.0
RPL7	-5186.0	8598.0
RPL8	3526.0	820.0
RPLP2	3550.0	3555.0
RPS13	7174.0	315.0
RPS14	4070.0	4443.0
RPS15	7253.0	6174.0
RPS16	6244.0	1119.0
RPS17	5667.0	7685.0
RPS18	4253.0	-526.0
RPS19	6565.0	-1215.0
RPS2	7322.0	4216.0
RPS21	7111.0	-6494.0
RPS25	4261.0	8455.0
RPS27A	-133.0	-1807.0
RPS28	7208.0	-396.0
RPS3	2340.0	4381.0
RPS3A	-3115.0	8824.0
RPS4X	2522.0	7391.0
RPS5	3848.0	7515.0
RPS6	-1700.0	8603.0
RPS6KA1	7703.0	4452.0
RPS6KA2	7237.0	-2956.0
RPS6KA3	-6111.0	8270.0
RPS6KA4	6661.0	-4264.0
RPS6KA5	2516.0	-3206.0
RPS6KA6	-5198.0	2828.0
RPS8	3874.0	7646.0
RPS9	-1719.0	-2555.0
RPTN	7767.0	-6542.0
RRAS	5761.0	6583.0
RUNX1	-5503.0	4154.0
RXRA	-5143.0	1552.0
SALL1	2139.0	-3148.0
SCN1A	1456.0	-3114.0
SCN1B	6408.0	7111.0
SCN2A	1026.0	1023.0
SCN2B	2199.0	709.0
SCN3A	-2507.0	1492.0
SCN3B	5796.0	-4481.0
SCN4A	3133.0	-3106.0
SCN4B	6329.0	2249.0
SCN5A	6040.0	-3056.0
SCN7A	1493.0	8215.0
SCN8A	3394.0	-3185.0
SDC2	-6850.0	7623.0
SDCBP	5668.0	4540.0
SEMA3A	-748.0	6343.0
SEMA3E	3287.0	6702.0
SEMA4A	4531.0	-6239.0
SEMA4D	-573.0	-5740.0
SEMA5A	-5557.0	182.0
SEMA6A	-6678.0	6683.0
SEMA6D	1160.0	8645.0
SEMA7A	6274.0	6320.0
SH3GL2	-6503.0	867.0
SH3KBP1	3805.0	5866.0
SHANK3	2553.0	-3878.0
SHC1	568.0	1962.0
SHC3	-3555.0	-3601.0
SHTN1	-7073.0	586.0
SIAH1	4474.0	5949.0
SIAH2	1504.0	-2759.0
SLC2A2	7902.0	2301.0
SLC2A4	8055.0	-2624.0
SLIT1	1701.0	-4596.0
SLIT2	737.0	-1675.0
SLIT3	6674.0	8430.0
SMAD2	2671.0	7154.0
SMAD3	-1639.0	-2520.0
SMAD4	3068.0	901.0
SMARCA4	-2170.0	4097.0
SMARCD3	7045.0	3943.0
SNW1	2102.0	8287.0
SOS1	-6566.0	7698.0
SOS2	-4341.0	7073.0
SPAG9	-2024.0	7533.0
SPI1	-2567.0	3642.0
SPINK9	-3007.0	5086.0
SPTA1	-2878.0	4811.0
SPTAN1	7051.0	7359.0
SPTB	7834.0	-4096.0
SPTBN1	4136.0	7630.0
SPTBN2	7922.0	-2952.0
SPTBN5	4733.0	-1695.0
SRC	-2657.0	-1643.0
SREBF1	-2758.0	-4433.0
SREBF2	4102.0	-4553.0
SRGAP1	3092.0	5935.0
SRGAP2	-1169.0	-688.0
SRGAP3	6392.0	4176.0
ST14	7899.0	2632.0
ST8SIA4	-6249.0	6735.0
STAT3	8126.0	4982.0
STX1A	2774.0	-2559.0
STX1B	3559.0	374.0
SUZ12	-1028.0	8662.0
TAL1	4405.0	2178.0
TBL1X	-7106.5	7510.5
TBL1XR1	-1156.0	6145.0
TCF12	-3463.0	6235.0
TCF3	7271.0	-5138.0
TCF4	2008.0	7220.0
TCHH	7184.0	-4848.0
TEAD1	-7124.0	1943.0
TFDP1	-6289.0	4476.0
TFDP2	7449.0	3780.0
TGFB1	-1851.0	6152.0
TGM1	-6369.0	-2212.0
TGS1	-5959.0	7769.0
THRAP3	6727.0	760.0
TIAM1	5502.0	5849.0
TLN1	-2076.0	-2832.0
TNF	-2778.0	4883.0
TREM2	-4021.0	2867.0
TRIO	-2249.0	-5133.0
TRPC1	-5396.0	1920.0
TRPC3	4682.0	5766.0
TRPC4	-3076.0	-324.0
TRPC5	555.0	-1490.0
TRPC6	-1685.0	1893.0
TSC22D1	-1662.0	8126.0
TYROBP	-4245.0	2276.0
UBA52	7488.0	-4269.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
UNC5A	-1287.0	-1741.0
UNC5B	6777.0	5303.0
UNC5C	-7233.0	-2826.0
UNC5D	-4908.0	-77.0
UPF2	-6949.0	7960.0
UPF3A	-1867.0	3076.0
UPF3B	3082.0	2946.0
USP33	-7002.0	7120.0
UTRN	5462.0	7245.0
VASP	-2568.0	4503.0
VAV2	2432.0	-843.0
VAV3	6942.0	5027.0
VLDLR	-6562.0	-563.0
WASL	-3989.0	7855.0
WDR5	3835.0	954.0
WWTR1	4978.0	8485.0
YAP1	-4463.0	1332.0
YES1	-120.0	7265.0
YY1	-5129.0	3260.0
ZNF335	-4080.0	-6129.0
ZNF467	8189.0	-6482.0
ZNF638	-7003.0	6985.0
ZSWIM8	6016.0	-3044.0

---

---

Membrane Trafficking

Membrane Trafficking

metric	value
setSize	570
pMANOVA	5.56e-12
p.adjustMANOVA	5.2e-10
s.dist	0.186
s.diabetes	-0.0642
s.mitoG	0.175
p.diabetes	0.00914
p.mitoG	1.15e-12

Top 20 genes

Gene	diabetes	mitoG
HSPA8	-7307	8180
UBB	-7104	8341
CAPZA1	-6942	8474
USO1	-6682	8749
SNAP29	-7150	7785
RAB6A	-6370	8664
ARCN1	-6138	8768
SEC24D	-6384	8428
TRIP11	-6424	8302
DYNLL1	-6952	7645
VPS54	-6687	7941
PICALM	-6252	8380
SNAP23	-6477	8059
RAB1A	-6571	7889
M6PR	-7125	7218
UBC	-6013	8514
ARPC3	-5747	8757
VPS37A	-5968	8308
TBC1D8B	-6069	8127
DENND5A	-6788	7092

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
AAK1	883.0	56.0
ACBD3	-2828.0	5524.0
ACTR10	268.0	6666.0
ACTR1A	965.0	5035.0
ACTR2	-5189.0	7356.0
ACTR3	-3716.0	8206.0
ADRB2	-6910.0	4340.0
AGFG1	-3918.0	7468.0
AGPAT3	-4447.0	-444.0
AGTR1	-3186.0	4400.0
AKT1	4859.0	7244.0
AKT2	-4939.0	3281.0
AKT3	-375.0	7862.0
ALS2	-6333.0	910.0
ALS2CL	4251.0	-5644.0
AMPH	-1364.0	554.0
ANK1	-2384.0	4523.0
ANK2	6760.0	923.0
ANK3	-300.0	4794.0
ANKRD27	1587.0	-3284.0
ANKRD28	8017.0	7539.0
AP1B1	5867.0	-3224.0
AP1G1	-6928.0	3255.0
AP1G2	-1203.0	-5382.0
AP1M1	2796.0	-3928.0
AP1M2	7170.0	-121.0
AP1S1	-667.0	-1428.0
AP1S2	-2308.0	7787.0
AP1S3	483.0	-6543.0
AP2A1	3192.0	-2941.0
AP2A2	-6231.0	249.0
AP2B1	-3990.0	7426.0
AP2M1	5073.0	2926.0
AP2S1	587.0	7094.0
AP3B1	3159.0	1998.0
AP3S1	-4458.0	6712.0
AP4B1	-5531.0	-776.0
AP4E1	-2091.0	-4473.0
AP4M1	2093.0	-5788.0
AP4S1	2217.0	1812.0
APOB	7604.0	5782.0
APP	-5115.0	6758.0
ARCN1	-6138.0	8768.0
ARF1	-5273.0	7470.0
ARF3	4831.5	-5103.5
ARF4	-6276.0	6071.0
ARF5	5403.0	222.0
ARF6	-804.0	229.0
ARFGAP1	-1727.0	-5894.0
ARFGAP2	5632.0	-3320.0
ARFGAP3	-1901.0	5934.0
ARFIP2	-3761.0	6326.0
ARFRP1	702.0	-6512.0
ARL1	-4284.0	8747.0
ARPC1A	-1009.0	-3070.0
ARPC2	-4512.0	8767.0
ARPC3	-5747.0	8757.0
ARPC4	3077.0	1525.0
ARPC5	920.0	7514.0
ARRB1	-6250.0	3030.0
ARRB2	-3644.0	681.0
ASPSCR1	-1896.0	1206.0
AVPR2	4980.0	2853.0
BET1L	2662.0	-5180.0
BICD1	-2065.0	6371.0
BICD2	-1620.0	4239.0
BIN1	-3934.0	-213.0
BLOC1S1	-6342.5	-164.5
BLOC1S3	-2239.0	-3153.0
BLOC1S4	-4206.0	-3968.0
BLOC1S6	-2843.0	6751.0
BNIP1	-2171.0	1583.0
BTC	7701.0	1951.0
C2CD5	6584.0	-6499.0
CALM1	-4401.0	8702.0
CAPZA1	-6942.0	8474.0
CAPZA2	-1687.0	8135.0
CAPZB	-2513.0	7203.0
CBL	-6462.0	4306.0
CCZ1	2495.5	3096.5
CCZ1B	2495.5	3096.5
CD3D	-3626.0	-15.0
CD3G	-1784.0	-3919.0
CD4	409.0	5008.0
CD55	-6863.0	6749.0
CD59	5509.5	-1796.5
CENPE	1973.0	460.0
CFTR	-6902.0	4865.0
CHM	-4490.0	8464.0
CHML	1162.0	5630.0
CHMP2A	3891.0	6246.0
CHMP2B	-3672.0	8606.0
CHMP3	-5181.5	8584.5
CHMP4B	7103.0	2636.0
CHMP4C	6678.0	1533.0
CHMP5	-4004.0	8542.0
CHMP6	4209.0	-2043.0
CHMP7	-57.0	-2549.0
CLINT1	-5244.0	4684.0
CLTA	-2807.0	2774.0
CLTB	4559.0	6461.0
CLTC	-4493.0	8248.0
CLVS1	-3816.0	2630.0
CLVS2	5315.0	-4006.0
CNIH1	-3991.0	8144.0
CNIH2	-2187.0	-4202.0
CNIH3	282.0	-4450.0
COG1	6605.0	-5589.0
COG2	549.0	4121.0
COG3	-5097.0	5605.0
COG4	1502.0	-5457.0
COG5	-2281.0	6788.0
COG6	-4517.0	730.0
COG7	6910.0	3017.0
COPA	488.0	2943.0
COPB1	-2848.0	7946.0
COPB2	-4259.0	8427.0
COPE	1600.0	4567.0
COPG1	-3891.0	3599.0
COPG2	2511.0	4641.0
COPS2	-5385.0	8716.0
COPS3	-904.0	8468.0
COPS4	-2811.0	8111.0
COPS5	430.0	6558.0
COPS6	1528.0	28.0
COPS7A	5878.0	-2436.0
COPS7B	-2394.0	-5916.0
COPS8	-147.0	1724.0
COPZ1	-4248.0	-67.0
COPZ2	3609.0	1137.0
CPD	5871.0	4487.0
CSNK1D	-1602.0	2506.0
CTSC	-1974.0	7696.0
CTSZ	-2861.0	2478.0
CTTN	211.0	2434.0
CUX1	-7126.0	4438.0
CYTH1	7147.0	5138.0
CYTH2	577.0	-1256.0
CYTH3	6160.0	6650.0
CYTH4	-6038.0	-2841.0
DAB2	-5689.0	1606.0
DCTN1	7218.0	-3098.0
DCTN2	2623.0	-2017.0
DCTN3	-715.0	689.0
DCTN4	-4133.0	7527.0
DCTN5	-4033.0	5094.0
DCTN6	4374.0	7565.0
DENND1A	-3578.0	-3992.0
DENND1B	-3640.0	6236.0
DENND1C	-4020.0	-3509.0
DENND2A	3171.0	5959.0
DENND2C	1598.0	3103.0
DENND2D	3945.0	-4019.0
DENND3	6819.0	-3851.0
DENND4A	7387.0	7310.0
DENND4B	5161.0	-4355.0
DENND4C	-5667.0	856.0
DENND5A	-6788.0	7092.0
DENND5B	-4587.0	3208.0
DENND6A	-3417.0	7381.0
DENND6B	3023.0	-6519.0
DNAJC6	6110.0	-873.0
DNASE2	-2379.0	-2179.0
DNM1	7171.0	3067.0
DNM2	-1598.0	5364.0
DNM3	6014.0	942.0
DTNBP1	6735.0	5583.0
DVL2	7754.0	-6212.0
DYNC1H1	4822.0	2594.0
DYNC1I1	3045.0	-5230.0
DYNC1I2	-251.0	7398.0
DYNC1LI1	2249.0	7292.0
DYNC1LI2	-1436.0	1861.0
DYNLL1	-6952.0	7645.0
DYNLL2	4932.0	-5028.0
EGF	-4765.0	-210.0
EGFR	-6023.0	1902.0
EPN1	-1121.0	-4468.0
EPN2	5737.0	3940.0
EPS15	-5197.0	5904.0
EPS15L1	3879.0	-4887.0
EXOC1	-2979.0	-335.0
EXOC2	7117.0	-1912.0
EXOC3	-5362.0	5791.0
EXOC4	7198.0	5527.0
EXOC5	-2682.0	8595.0
EXOC6	-6197.0	3478.0
EXOC7	2029.0	3647.0
EXOC8	-1501.0	-3511.0
F5	-5716.0	-1378.0
F8	-688.0	7499.0
FCHO1	3015.0	1348.0
FCHO2	6592.0	5417.0
FNBP1	-4982.0	-2153.0
FNBP1L	3122.0	4349.0
FOLR1	-6908.0	-283.0
FTL	-6693.0	-6771.0
FZD4	6121.0	5562.0
GABARAP	-5579.0	8282.0
GABARAPL2	-1204.0	2829.0
GAK	-4211.0	5123.0
GALNT1	-6827.0	6806.0
GALNT2	-4331.0	2581.0
GAPVD1	-4780.0	2418.0
GBF1	-6681.0	3356.0
GCC1	3057.0	524.0
GCC2	-3855.0	7972.0
GDI1	2238.0	3292.0
GDI2	-5894.0	8074.0
GGA1	-539.0	-4988.0
GGA2	2677.0	-3451.0
GGA3	-3482.0	-6019.0
GJA1	-2103.0	-4151.0
GJA3	1739.0	-2907.0
GJA4	7104.0	-3166.0
GJA5	1705.0	2064.0
GJA8	1944.0	-1336.0
GJB1	-2164.0	2821.0
GJB2	-4828.0	3699.0
GJB3	-2101.0	4605.0
GJB6	5153.0	-297.0
GJC1	-360.0	8269.0
GJC2	1990.0	3378.0
GJD3	4989.0	129.0
GJD4	3782.0	-1724.0
GNS	8072.0	1691.0
GOLGA1	-6570.0	3706.0
GOLGA4	-3479.0	-714.0
GOLGA5	746.0	8085.0
GOLGB1	-4541.0	3630.0
GOLIM4	-2600.0	7173.0
GORASP1	1404.0	-5586.0
GOSR1	2520.0	5197.0
GOSR2	-4613.5	7118.5
GPS1	-1275.0	3233.0
GRB2	3285.0	1922.0
GRIA1	3840.0	-983.0
GRK2	-1123.0	7008.0
GRK3	-2167.0	-104.0
HBEGF	-6694.0	-80.0
HGS	-1920.0	704.0
HIP1	1316.0	7975.0
HIP1R	7828.0	-2141.0
HPS1	2385.0	-4872.0
HPS4	7159.0	-6710.0
HSPA8	-7307.0	8180.0
IGF2R	7820.0	-602.0
IL7R	-5696.0	8026.0
ITSN1	-2643.0	3175.0
ITSN2	-5674.0	5013.0
KDELR1	-5082.0	-3141.0
KDELR2	-4969.0	8520.0
KDELR3	3008.0	2539.0
KIAA0319	1289.0	-5453.0
KIF11	4262.0	-1098.0
KIF12	-3419.0	-6372.0
KIF13B	6407.0	-5191.0
KIF15	91.0	-5193.0
KIF16B	-2844.0	3593.0
KIF18A	-2035.0	4687.0
KIF18B	4824.0	632.0
KIF19	1923.0	-4963.0
KIF1A	5374.0	5302.0
KIF1B	2260.0	5141.0
KIF1C	-812.0	669.0
KIF20A	3022.0	-1094.0
KIF20B	-7215.0	5043.0
KIF21A	-5621.0	7768.0
KIF21B	1267.0	-2504.0
KIF22	-925.0	-1002.0
KIF23	6834.0	-2775.0
KIF26A	3470.0	3765.0
KIF26B	6327.0	-720.0
KIF27	-5722.0	1135.0
KIF2A	1251.0	7652.0
KIF2C	2591.0	-1946.0
KIF3A	-5126.0	3351.0
KIF3B	-3223.0	6725.0
KIF3C	-3455.0	5074.0
KIF4A	1014.0	6024.0
KIF5A	-5260.0	-5278.0
KIF5B	-1547.0	8819.0
KIF5C	6290.0	2117.0
KIF6	5572.0	-4169.0
KIF9	55.0	-2135.0
KIFAP3	41.0	8075.0
KIFC1	8091.0	-6629.0
KIFC2	5216.0	-6709.0
KLC1	143.0	-5336.0
KLC2	6949.0	-4707.0
KLC3	7232.0	-1031.0
KLC4	-6395.0	-2860.0
LDLR	4229.0	3193.0
LDLRAP1	6322.0	5636.0
LMAN1	-4772.0	8101.0
LMAN2	-6960.0	209.0
LMAN2L	-6950.0	-4458.0
LNPEP	4116.0	7467.0
LRP2	-7179.0	-3908.0
M6PR	-7125.0	7218.0
MADD	-4200.0	-2939.0
MAN1A1	-4332.0	3367.0
MAN1A2	-1067.0	6604.0
MAN1C1	6879.0	7174.0
MAN2A1	8162.0	5453.0
MAN2A2	-1276.0	3170.0
MAP1LC3B	3858.5	3812.5
MCFD2	-4954.0	6881.0
MIA2	-5486.0	8570.0
MON1A	-1003.0	-43.0
MON1B	2133.0	-4380.0
MVB12A	5433.0	3851.0
MVB12B	-659.0	-5360.0
MYH9	7189.0	7115.0
MYO1C	7502.0	5436.0
MYO5A	-7077.0	3216.0
MYO6	-5300.0	6176.0
NAA30	-1919.0	4544.0
NAA35	22.0	260.0
NAA38	-4146.0	-1683.0
NAPA	5425.0	1632.0
NAPB	2953.0	-4029.0
NAPG	3323.0	2180.0
NBAS	-6309.0	-4474.0
NECAP1	-79.0	5214.0
NECAP2	4045.0	1923.0
NEDD8	-4578.0	7681.0
NSF	4215.0	7420.0
OCRL	3974.0	593.0
OPTN	8052.0	6703.0
PACSIN1	1585.0	2292.0
PACSIN2	7548.0	3572.0
PACSIN3	7735.0	-4476.0
PAFAH1B1	-3995.0	8266.0
PAFAH1B2	-1657.0	7964.0
PAFAH1B3	4821.0	-71.0
PICALM	-6252.0	8380.0
PIK3C2A	-262.0	8592.0
PIP5K1C	6778.0	694.0
PLA2G4A	7058.0	5276.0
PLA2G6	-5964.0	-5304.0
PLIN3	5004.0	-4323.0
POLG	754.0	-4942.0
PPP6C	1874.0	5889.0
PPP6R1	-4706.0	-2647.0
PPP6R3	-5114.0	7597.0
PREB	-6991.0	-1923.0
PRKAA2	-1063.0	2375.0
PRKAB1	7696.0	1290.0
PRKAB2	4730.0	-4503.0
PRKAG1	1680.0	-288.0
PRKAG2	7790.0	-3443.0
PRKAG3	5892.0	-1774.0
PUM1	-856.0	-3002.0
RAB10	-5609.0	8060.0
RAB11A	-3713.0	8250.0
RAB11B	4309.0	4748.0
RAB12	-1057.0	8176.0
RAB13	3302.5	1698.5
RAB14	-4203.0	5569.0
RAB18	-6358.0	6912.0
RAB1A	-6571.0	7889.0
RAB1B	-80.0	-4574.0
RAB21	-2903.0	7574.0
RAB27A	7997.0	1512.0
RAB27B	-4838.0	5533.0
RAB30	6435.0	5622.0
RAB31	3839.0	8541.0
RAB33B	2372.0	6149.0
RAB35	-1301.0	5850.0
RAB36	690.0	-5670.0
RAB38	-6913.0	3044.0
RAB39A	-2191.0	1676.0
RAB39B	-1021.0	6431.0
RAB3A	-21.0	-1948.0
RAB3GAP1	1288.0	3646.0
RAB3GAP2	1771.0	-2399.0
RAB3IL1	-6837.0	-1600.0
RAB43	8116.0	1573.0
RAB4A	-4186.0	1766.0
RAB5A	1537.0	7332.0
RAB5B	5887.0	3206.0
RAB5C	3703.0	3375.0
RAB6A	-6370.0	8664.0
RAB6B	7529.0	1278.0
RAB7A	-5898.0	8083.0
RAB7B	-5496.0	5451.0
RAB8A	-855.0	2596.0
RAB8B	3129.0	7133.0
RAB9A	-412.0	7818.0
RABEP1	-1962.0	2952.0
RABEPK	2166.0	960.0
RABGAP1	-2389.0	6981.0
RABGEF1	5972.0	6956.0
RAC1	-1258.0	4008.0
RACGAP1	6146.0	-2445.0
RALA	-5149.0	6748.0
RALGAPA2	4862.0	2010.0
RALGAPB	-6085.0	4766.0
REPS1	1567.0	6807.0
REPS2	-6894.0	6233.0
RGP1	6921.0	-4505.0
RHOBTB3	7579.0	5682.0
RHOQ	7462.0	6211.0
RIC1	1268.0	5479.0
RIN1	3110.0	1704.0
RIN2	-2547.0	4612.0
RIN3	-4871.0	-311.0
RINL	-6388.0	-1892.0
RINT1	-2729.0	-5208.0
RPS27A	-133.0	-1807.0
SAR1B	-3423.0	7668.0
SBF1	5827.0	-6278.0
SBF2	7073.0	3902.0
SCARB2	6376.0	7312.0
SCFD1	-5793.0	7896.0
SCOC	-2294.0	8643.0
SEC13	-1432.0	3604.0
SEC16A	-1511.0	3230.0
SEC16B	8007.0	2261.0
SEC22A	3566.0	5061.0
SEC22B	-4623.0	5601.0
SEC22C	5970.0	-5637.0
SEC23A	-3552.0	8413.0
SEC23IP	-1834.0	5924.0
SEC24A	159.0	5121.0
SEC24B	-570.0	-3344.0
SEC24C	-5965.0	-1916.0
SEC24D	-6384.0	8428.0
SEC31A	835.0	-552.0
SERPINA1	8234.0	4905.0
SFN	3916.0	5704.0
SGIP1	6996.0	-6306.0
SH3D19	-6654.0	1762.0
SH3GL1	993.0	-4650.0
SH3GL2	-6503.0	867.0
SH3KBP1	3805.0	5866.0
SLC2A4	8055.0	-2624.0
SLC2A8	8092.0	-6699.0
SNAP23	-6477.0	8059.0
SNAP29	-7150.0	7785.0
SNAP91	4566.0	3611.0
SNAPIN	2078.0	4336.0
SNF8	2397.0	-3270.0
SNX18	413.0	18.0
SNX2	-4579.0	8581.0
SNX5	998.0	8207.0
SNX9	3993.0	5456.0
SORT1	6873.0	3383.0
SPTA1	-2878.0	4811.0
SPTAN1	7051.0	7359.0
SPTB	7834.0	-4096.0
SPTBN1	4136.0	7630.0
SPTBN2	7922.0	-2952.0
SPTBN5	4733.0	-1695.0
SRC	-2657.0	-1643.0
STAM	-2360.0	4932.0
STAM2	494.0	2564.0
STON1	3948.5	7204.5
STON2	2271.0	1103.0
STX16	-6431.5	-5194.5
STX17	4886.0	-671.0
STX18	-6160.0	5652.0
STX4	-3184.0	-4491.0
STX5	-4974.0	-4939.0
STX6	2498.0	2382.0
STXBP3	728.0	7644.0
SURF4	-5939.0	2804.0
SYNJ1	2013.0	4478.0
SYNJ2	3594.0	6905.0
SYT1	-2989.0	-4969.0
SYT11	727.0	3892.0
SYT2	-2226.0	-4027.0
SYT9	5485.0	1871.0
SYTL1	5660.0	-4878.0
TACR1	-1916.0	-1112.0
TBC1D1	83.0	8056.0
TBC1D10A	-3577.0	-5886.0
TBC1D10B	-4687.0	-4211.0
TBC1D10C	4785.0	-3612.0
TBC1D13	-5658.0	-4914.0
TBC1D14	2183.0	2622.0
TBC1D15	1925.0	6934.0
TBC1D16	8187.0	-3920.0
TBC1D17	6335.0	-6244.0
TBC1D2	7607.0	-1821.0
TBC1D20	1958.0	574.0
TBC1D24	4169.5	-1717.5
TBC1D25	-3737.0	-1337.0
TBC1D4	3817.0	1800.0
TBC1D7	-136.0	3571.0
TBC1D8B	-6069.0	8127.0
TF	6988.0	4696.0
TFG	-5471.0	5860.0
TFRC	-4827.0	4702.0
TGFA	4979.0	2380.0
TGOLN2	-6334.0	4798.0
TJP1	4021.0	8531.0
TMED10	-6147.0	6432.0
TMED2	-2351.0	6953.0
TMED3	-6313.0	3992.0
TMED7	-4902.5	7760.5
TMED9	-5309.0	-1036.0
TMEM115	1699.0	-4432.0
TMF1	-1973.0	8658.0
TOR1A	-1140.0	6598.0
TOR1B	4430.0	17.0
TPD52	-2660.5	6366.5
TPD52L1	2889.0	7584.0
TRAPPC1	-1429.0	4746.0
TRAPPC10	2000.0	2916.0
TRAPPC11	1264.0	6074.0
TRAPPC12	6523.0	-3711.0
TRAPPC13	-5406.0	5577.0
TRAPPC2	-3263.0	6403.0
TRAPPC2L	3633.0	-4527.0
TRAPPC3	593.0	5718.0
TRAPPC4	-1321.0	-410.0
TRAPPC5	-2311.0	-1472.0
TRAPPC6A	7806.0	-5370.0
TRAPPC6B	978.0	7705.0
TRAPPC8	-6092.0	7767.0
TRAPPC9	1611.0	-4039.0
TRIP10	6118.0	-2284.0
TRIP11	-6424.0	8302.0
TSC1	6280.0	-2516.0
TSC2	5344.0	-2751.0
TSG101	-708.0	7980.0
TXNDC5	1391.0	-669.0
UBA52	7488.0	-4269.0
UBAP1	-6158.0	7653.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
UBQLN1	-6727.0	6938.0
UBQLN2	1361.0	868.0
ULK1	7107.0	-1830.0
USE1	3688.0	-3547.0
USO1	-6682.0	8749.0
USP6NL	5290.0	6675.0
VAMP2	8086.5	-3275.5
VAMP3	1693.0	5955.0
VAMP4	-908.0	852.0
VAMP8	-3005.0	5301.0
VPS25	-306.0	6834.0
VPS28	4871.0	5243.0
VPS36	5728.0	8042.0
VPS37A	-5968.0	8308.0
VPS37B	5639.0	2161.0
VPS37C	5395.0	-224.0
VPS37D	-1556.0	-3123.0
VPS45	-788.0	4784.0
VPS4A	-5731.5	7213.5
VPS4B	2398.0	6175.0
VPS51	3048.0	-6458.0
VPS52	-3308.0	-5643.0
VPS53	424.0	7261.0
VPS54	-6687.0	7941.0
VTA1	-2777.0	104.0
VTI1A	-1225.0	3613.0
WASL	-3989.0	7855.0
WNT5A	5498.0	-739.0
YIPF6	-4393.0	6442.0
YKT6	2462.0	3655.0
YWHAB	-4723.0	8579.0
YWHAE	-2079.0	7315.0
YWHAG	-5348.0	1700.0
YWHAH	-6051.0	7949.0
YWHAQ	3046.0	8675.0
YWHAZ	-5614.0	8512.0
ZW10	-6443.0	-752.0

---

---

Fc epsilon receptor (FCERI) signaling

Fc epsilon receptor (FCERI) signaling

metric	value
setSize	143
pMANOVA	6.39e-12
p.adjustMANOVA	5.6e-10
s.dist	0.378
s.diabetes	-0.198
s.mitoG	0.322
p.diabetes	4.42e-05
p.mitoG	3.24e-11

Top 20 genes

Gene	diabetes	mitoG
IGHV1-69	-7353.5	8845.5
IGKV4-1	-7301.0	8840.0
PSMC6	-6851.0	8666.0
UBB	-7104.0	8341.0
PSME4	-6830.0	8511.0
SKP1	-6803.0	8394.0
PSMD1	-6497.0	8619.0
PSMD12	-6149.0	8628.0
PSMD7	-6943.0	7625.0
PSMA1	-6705.0	7838.0
TAB2	-7040.0	7307.0
UBC	-6013.0	8514.0
IGKV5-2	-5895.0	8671.0
PSMC4	-6423.0	7920.0
SOS1	-6566.0	7698.0
PSMD14	-6080.0	8262.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
LYN	-4685.0	8216.0
CALM1	-4401.0	8702.0

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
AHCYL1	-5585.0	5114.0
BCL10	-3598.0	5942.0
BTK	-5279.0	5486.0
BTRC	3218.0	-5334.0
CALM1	-4401.0	8702.0
CARD11	-3020.0	3028.0
CDC34	-806.0	2346.0
CHUK	-3701.0	8556.0
CUL1	-2997.0	6875.0
FBXW11	-3788.0	3125.0
FCER1G	-3782.0	3932.0
FOS	827.0	3751.0
FYN	-2200.0	6221.0
GAB2	-717.0	7438.0
GRAP2	-2907.0	5211.0
GRB2	3285.0	1922.0
HRAS	1503.0	-318.0
IGHV1-69	-7353.5	8845.5
IGHV2-5	4395.0	4965.0
IGHV2-70	4395.0	4965.0
IGHV7-81	517.5	7570.5
IGKC	-2925.0	7318.0
IGKV1-12	2052.5	4944.5
IGKV1-17	2052.5	4944.5
IGKV1-39	2052.5	4944.5
IGKV1D-12	2052.5	4944.5
IGKV1D-39	2052.5	4944.5
IGKV2-30	101.5	8396.5
IGKV2D-30	101.5	8396.5
IGKV4-1	-7301.0	8840.0
IGKV5-2	-5895.0	8671.0
IGLV4-60	-3537.5	3617.5
IGLV4-69	-3537.5	3617.5
IKBKB	-1785.0	-5829.0
IKBKG	3700.0	-677.0
ITK	-3536.0	2982.0
ITPR1	-2727.0	2512.0
ITPR2	4185.0	-2206.0
ITPR3	7844.0	5234.0
JUN	581.0	5314.0
KRAS	-752.0	8587.0
LAT	1869.0	-481.0
LAT2	-2578.0	2305.0
LCP2	-5980.0	1266.0
LYN	-4685.0	8216.0
MALT1	-2981.0	1806.0
MAP2K4	2621.0	5572.0
MAP2K7	3505.0	-3383.0
MAP3K1	5322.0	-960.0
MAP3K7	1594.0	7480.0
MAPK1	-3928.0	6920.0
MAPK10	-2089.0	-137.0
MAPK3	5390.0	5167.0
MAPK8	-3252.0	1695.0
MAPK9	2849.0	6624.0
MS4A2	4446.0	3088.0
NFATC1	6099.0	7170.0
NFATC2	4913.0	-5797.0
NFATC3	-5299.0	6496.0
NFKB1	5449.0	4035.0
NFKBIA	1631.0	4830.0
NRAS	3837.0	7903.0
PAK1	-886.0	5458.0
PAK2	-4906.0	6708.0
PDPK1	-4074.0	1936.0
PIK3CA	-6347.0	2923.0
PIK3CB	-1756.0	1880.0
PIK3R1	-839.0	8363.0
PIK3R2	1669.5	-3969.5
PLCG1	8067.0	-4962.0
PLCG2	-5287.0	2474.0
PPP3CA	5123.0	6939.0
PPP3CB	-1150.0	4729.0
PPP3R1	2835.5	8199.5
PRKCQ	-2002.0	-3514.0
PSMA1	-6705.0	7838.0
PSMA2	-5464.5	6058.5
PSMA3	-3145.0	7801.0
PSMA4	-6074.0	4688.0
PSMA5	-6660.0	4497.0
PSMA6	-1954.0	8445.0
PSMA7	1612.0	7052.0
PSMA8	649.0	-4004.0
PSMB1	-5281.0	5936.0
PSMB10	3752.0	-908.0
PSMB11	1977.0	-5501.0
PSMB2	1472.0	-4144.0
PSMB3	-3388.0	5539.0
PSMB4	-4941.0	-5852.0
PSMB5	-1638.0	-2409.0
PSMB6	1806.0	-1845.0
PSMB7	-4628.0	-657.0
PSMB8	1080.0	-3793.0
PSMB9	5987.0	-4708.0
PSMC1	-1312.0	4327.0
PSMC2	-6765.0	4648.0
PSMC3	-4285.0	3386.0
PSMC4	-6423.0	7920.0
PSMC5	-4831.0	1120.0
PSMC6	-6851.0	8666.0
PSMD1	-6497.0	8619.0
PSMD10	-1613.0	2576.0
PSMD11	-6873.0	5201.0
PSMD12	-6149.0	8628.0
PSMD13	1898.0	5044.0
PSMD14	-6080.0	8262.0
PSMD2	-6702.0	-3836.0
PSMD3	-2532.0	-3242.0
PSMD4	-5648.0	4994.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
PSMD7	-6943.0	7625.0
PSMD8	1978.0	7546.0
PSMD9	7707.5	-894.5
PSME1	2907.0	5905.0
PSME2	1270.0	-4595.0
PSME3	752.0	7366.0
PSME4	-6830.0	8511.0
PSMF1	5087.0	4771.0
RAC1	-1258.0	4008.0
RASGRP1	-370.0	-2734.0
RASGRP2	-326.0	-409.0
RASGRP4	-3063.0	1538.0
RELA	2579.0	-2368.0
RPS27A	-133.0	-1807.0
SHC1	568.0	1962.0
SKP1	-6803.0	8394.0
SOS1	-6566.0	7698.0
SYK	-6921.0	4480.0
TAB1	7839.0	-5339.0
TAB2	-7040.0	7307.0
TAB3	3966.0	5424.0
TEC	-5516.0	6783.0
TRAF6	1082.0	6626.0
TXK	861.0	-4279.0
UBA52	7488.0	-4269.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
UBE2D1	5638.0	3025.0
UBE2D2	-935.0	6690.0
VAV1	-4395.0	5076.0
VAV2	2432.0	-843.0
VAV3	6942.0	5027.0

---

---

Signaling by the B Cell Receptor (BCR)

Signaling by the B Cell Receptor (BCR)

metric	value
setSize	123
pMANOVA	8.95e-12
p.adjustMANOVA	7.37e-10
s.dist	0.406
s.diabetes	-0.227
s.mitoG	0.337
p.diabetes	1.34e-05
p.mitoG	1.17e-10

Top 20 genes

Gene	diabetes	mitoG
IGHV1-69	-7353.5	8845.5
IGKV4-1	-7301.0	8840.0
PSMC6	-6851.0	8666.0
UBB	-7104.0	8341.0
PSME4	-6830.0	8511.0
SKP1	-6803.0	8394.0
PSMD1	-6497.0	8619.0
PSMD12	-6149.0	8628.0
PSMD7	-6943.0	7625.0
PSMA1	-6705.0	7838.0
UBC	-6013.0	8514.0
IGKV5-2	-5895.0	8671.0
PSMC4	-6423.0	7920.0
SOS1	-6566.0	7698.0
PSMD14	-6080.0	8262.0
RASGRP3	-6128.0	7243.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
NCK1	-4610.0	8438.0
LYN	-4685.0	8216.0

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
AHCYL1	-5585.0	5114.0
BCL10	-3598.0	5942.0
BLNK	6748.0	-965.0
BTK	-5279.0	5486.0
BTRC	3218.0	-5334.0
CALM1	-4401.0	8702.0
CARD11	-3020.0	3028.0
CD19	-2666.0	-3652.0
CD22	-4125.0	1554.0
CD79A	-4689.0	2648.0
CD79B	-2701.0	2433.0
CHUK	-3701.0	8556.0
CUL1	-2997.0	6875.0
DAPP1	-2716.0	5499.0
FBXW11	-3788.0	3125.0
FKBP1A	-2857.5	-1534.5
FYN	-2200.0	6221.0
GRB2	3285.0	1922.0
HRAS	1503.0	-318.0
IGHM	5659.0	-3544.0
IGHV1-69	-7353.5	8845.5
IGHV2-5	4395.0	4965.0
IGHV2-70	4395.0	4965.0
IGHV7-81	517.5	7570.5
IGKC	-2925.0	7318.0
IGKV1-12	2052.5	4944.5
IGKV1-17	2052.5	4944.5
IGKV1-39	2052.5	4944.5
IGKV1D-12	2052.5	4944.5
IGKV1D-39	2052.5	4944.5
IGKV2-30	101.5	8396.5
IGKV2D-30	101.5	8396.5
IGKV4-1	-7301.0	8840.0
IGKV5-2	-5895.0	8671.0
IKBKB	-1785.0	-5829.0
IKBKG	3700.0	-677.0
ITPR1	-2727.0	2512.0
ITPR2	4185.0	-2206.0
ITPR3	7844.0	5234.0
KRAS	-752.0	8587.0
LYN	-4685.0	8216.0
MALT1	-2981.0	1806.0
MAP3K7	1594.0	7480.0
NCK1	-4610.0	8438.0
NFATC1	6099.0	7170.0
NFATC2	4913.0	-5797.0
NFATC3	-5299.0	6496.0
NFKB1	5449.0	4035.0
NFKBIA	1631.0	4830.0
NFKBIB	3850.0	467.0
NFKBIE	-4334.0	-123.0
NRAS	3837.0	7903.0
ORAI1	5373.0	-3312.0
ORAI2	4113.0	4514.0
PIK3AP1	-6075.0	3775.0
PIK3CD	-1968.0	1889.0
PIK3R1	-839.0	8363.0
PLCG2	-5287.0	2474.0
PPIA	4868.0	-469.0
PPP3CA	5123.0	6939.0
PPP3CB	-1150.0	4729.0
PPP3R1	2835.5	8199.5
PRKCB	-5598.0	5660.0
PSMA1	-6705.0	7838.0
PSMA2	-5464.5	6058.5
PSMA3	-3145.0	7801.0
PSMA4	-6074.0	4688.0
PSMA5	-6660.0	4497.0
PSMA6	-1954.0	8445.0
PSMA7	1612.0	7052.0
PSMA8	649.0	-4004.0
PSMB1	-5281.0	5936.0
PSMB10	3752.0	-908.0
PSMB11	1977.0	-5501.0
PSMB2	1472.0	-4144.0
PSMB3	-3388.0	5539.0
PSMB4	-4941.0	-5852.0
PSMB5	-1638.0	-2409.0
PSMB6	1806.0	-1845.0
PSMB7	-4628.0	-657.0
PSMB8	1080.0	-3793.0
PSMB9	5987.0	-4708.0
PSMC1	-1312.0	4327.0
PSMC2	-6765.0	4648.0
PSMC3	-4285.0	3386.0
PSMC4	-6423.0	7920.0
PSMC5	-4831.0	1120.0
PSMC6	-6851.0	8666.0
PSMD1	-6497.0	8619.0
PSMD10	-1613.0	2576.0
PSMD11	-6873.0	5201.0
PSMD12	-6149.0	8628.0
PSMD13	1898.0	5044.0
PSMD14	-6080.0	8262.0
PSMD2	-6702.0	-3836.0
PSMD3	-2532.0	-3242.0
PSMD4	-5648.0	4994.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
PSMD7	-6943.0	7625.0
PSMD8	1978.0	7546.0
PSMD9	7707.5	-894.5
PSME1	2907.0	5905.0
PSME2	1270.0	-4595.0
PSME3	752.0	7366.0
PSME4	-6830.0	8511.0
PSMF1	5087.0	4771.0
PTPN6	-1098.0	2140.0
RASGRP1	-370.0	-2734.0
RASGRP3	-6128.0	7243.0
REL	-2309.0	7411.0
RELA	2579.0	-2368.0
RPS27A	-133.0	-1807.0
SH3KBP1	3805.0	5866.0
SKP1	-6803.0	8394.0
SOS1	-6566.0	7698.0
STIM1	7832.0	6223.0
SYK	-6921.0	4480.0
TRPC1	-5396.0	1920.0
UBA52	7488.0	-4269.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
VAV1	-4395.0	5076.0

---

---

rRNA processing

rRNA processing

metric	value
setSize	176
pMANOVA	9.46e-12
p.adjustMANOVA	7.37e-10
s.dist	0.296
s.diabetes	0.0433
s.mitoG	0.292
p.diabetes	0.322
p.mitoG	2.31e-11

Top 20 genes

Gene	diabetes	mitoG
NCL	6850	8762
RPL35	5949	8834
FAU	6809	7710
MT-ND5	6025	8007
UTP20	8200	5794
XRN2	7433	6374
RPS15	7253	6174
RPS17	5667	7685
MT-ND1	5618	7323
MT-CO1	6781	5983
NIP7	5420	6991
RPS25	4261	8455
EXOSC9	4661	7068
RRP1	5293	6186
UTP15	4856	6673
RPL28	6714	4753
RPL26	3650	8722
RPL38	5601	5675
RPL19	4654	6782
RPS2	7322	4216

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
BMS1	-5831.0	3306.0
BOP1	-3585.0	976.0
BYSL	-4542.0	5843.0
C1D	-5321.0	8041.0
CSNK1D	-1602.0	2506.0
CSNK1E	5383.5	5055.5
DCAF13	-6109.0	5418.0
DDX21	-5116.0	8276.0
DDX47	3030.0	755.0
DDX49	4404.0	-1145.0
DDX52	-4060.0	7194.0
DHX37	-533.0	-1936.0
DIMT1	2968.0	-3709.0
DIS3	-6175.0	6931.0
DKC1	-5095.0	7179.0
EBNA1BP2	-2177.0	6468.0
ELAC2	3639.0	1857.0
EMG1	-6093.0	-1167.0
ERI1	-5053.0	4453.0
EXOSC1	-2448.0	7613.0
EXOSC10	1760.0	8346.0
EXOSC2	3957.0	3800.0
EXOSC3	-1469.0	-3935.0
EXOSC4	-3182.0	-4923.0
EXOSC5	4223.0	-3378.0
EXOSC7	6973.0	-5606.0
EXOSC8	6788.0	616.0
EXOSC9	4661.0	7068.0
FAU	6809.0	7710.0
FBL	6041.0	-6202.0
FTSJ3	364.0	-330.0
GAR1	642.0	-352.0
GNL3	-4340.0	6867.0
HEATR1	-6514.0	7682.0
HSD17B10	3539.0	5976.0
IMP3	3952.0	-6093.0
IMP4	186.0	5570.0
ISG20L2	-4479.0	3406.0
KRR1	-4385.0	7088.0
LAS1L	1684.0	1715.0
LTV1	-279.5	6894.5
MPHOSPH10	-5904.0	8696.0
MPHOSPH6	-3203.0	7923.0
MRM1	6500.0	-222.0
MRM2	-3612.0	-2742.0
MRM3	2274.0	3059.0
MT-ATP6	-5818.0	8744.0
MT-ATP8	3277.0	6153.0
MT-CO1	6781.0	5983.0
MT-CO2	293.0	-1711.0
MT-CO3	2273.0	6269.0
MT-CYB	3577.0	8110.0
MT-ND1	5618.0	7323.0
MT-ND2	-1693.0	8626.0
MT-ND3	1835.0	8689.0
MT-ND4	1752.0	7883.0
MT-ND4L	2829.0	8068.0
MT-ND5	6025.0	8007.0
MTERF4	-6002.0	2934.0
MTREX	-6973.0	5247.0
NAT10	2042.0	-2361.0
NCL	6850.0	8762.0
NHP2	-5332.0	6281.0
NIP7	5420.0	6991.0
NOB1	-3003.0	2527.0
NOC4L	5961.0	1908.0
NOL11	-4046.0	6580.0
NOL12	-3477.5	6109.5
NOL6	7943.0	-3108.0
NOL9	-1832.0	-148.0
NOP10	2308.0	5890.0
NOP14	-2312.0	6526.0
NOP56	-875.0	1129.0
NOP58	-4438.0	5964.0
NSUN4	1070.0	-2056.0
PDCD11	-4002.0	-3015.0
PELP1	1681.0	-4851.0
PES1	2890.0	6091.0
PNO1	-5524.0	8385.0
PRORP	-4253.5	5249.5
PWP2	4987.5	-4444.5
RBM28	-5098.0	2336.0
RCL1	5218.0	4620.0
RIOK1	-1297.0	7015.0
RIOK2	-670.0	7303.0
RIOK3	-3202.0	8097.0
RPL11	5748.0	1403.0
RPL12	6107.0	-5604.0
RPL13	5686.0	-3760.0
RPL14	5110.0	-1875.0
RPL18	2523.0	-625.0
RPL18A	4545.0	-3218.0
RPL19	4654.0	6782.0
RPL21	-1686.0	8463.0
RPL22	2365.0	459.0
RPL22L1	-5123.0	-6294.0
RPL23	-205.0	4253.0
RPL24	-409.0	6813.0
RPL26	3650.0	8722.0
RPL28	6714.0	4753.0
RPL29	2613.0	4628.0
RPL3	5378.0	1155.0
RPL30	4372.0	3664.0
RPL31	6732.0	-1507.0
RPL32	2989.0	8728.0
RPL34	661.0	7140.0
RPL35	5949.0	8834.0
RPL35A	-1509.0	6565.0
RPL36	7543.0	-2424.0
RPL36A	-5983.0	4837.0
RPL36AL	1793.0	-2074.0
RPL37	2109.0	-667.0
RPL38	5601.0	5675.0
RPL3L	-5986.0	4937.0
RPL4	2582.0	8471.0
RPL6	572.0	7594.0
RPL7	-5186.0	8598.0
RPL8	3526.0	820.0
RPLP2	3550.0	3555.0
RPP14	-1705.0	2028.0
RPP21	1368.0	437.0
RPP25	5432.0	3890.0
RPP30	-4567.0	4289.0
RPP38	-3284.0	7004.0
RPP40	-5546.0	2654.0
RPS13	7174.0	315.0
RPS14	4070.0	4443.0
RPS15	7253.0	6174.0
RPS16	6244.0	1119.0
RPS17	5667.0	7685.0
RPS18	4253.0	-526.0
RPS19	6565.0	-1215.0
RPS2	7322.0	4216.0
RPS21	7111.0	-6494.0
RPS25	4261.0	8455.0
RPS27A	-133.0	-1807.0
RPS28	7208.0	-396.0
RPS3	2340.0	4381.0
RPS3A	-3115.0	8824.0
RPS4X	2522.0	7391.0
RPS5	3848.0	7515.0
RPS6	-1700.0	8603.0
RPS8	3874.0	7646.0
RPS9	-1719.0	-2555.0
RRP1	5293.0	6186.0
RRP36	3453.0	244.0
RRP7A	-1466.0	3721.0
RRP9	2614.0	851.0
SENP3	-2124.5	3519.5
SNU13	-4083.0	7577.0
TBL3	5799.0	-3253.0
TEX10	5529.0	1840.0
TFB1M	-154.0	-4984.0
THUMPD1	-2693.0	6882.0
TRMT10C	-5437.0	8416.0
TRMT112	-6614.0	-1009.0
TSR1	-4634.0	2623.0
TSR3	4228.0	-5856.0
UBA52	7488.0	-4269.0
UTP11	-3324.0	3075.0
UTP14A	-755.5	3859.5
UTP14C	-755.5	3859.5
UTP15	4856.0	6673.0
UTP18	1908.0	6014.0
UTP20	8200.0	5794.0
UTP3	-2706.0	6844.0
UTP4	-4384.0	4038.0
UTP6	-3727.0	5591.0
WDR12	-3943.0	1434.0
WDR18	-5000.0	-3150.0
WDR3	-6076.0	2575.0
WDR36	5285.0	-1626.0
WDR43	2708.0	8166.0
WDR46	5078.0	-4710.0
WDR75	-3646.0	8219.0
XRN2	7433.0	6374.0

---

---

Post-translational protein modification

Post-translational protein modification

metric	value
setSize	1238
pMANOVA	1.16e-11
p.adjustMANOVA	8.56e-10
s.dist	0.132
s.diabetes	-0.0685
s.mitoG	0.112
p.diabetes	6.11e-05
p.mitoG	4.99e-11

Top 20 genes

Gene	diabetes	mitoG
HNRNPC	-7051	8787
HSP90B1	-7279	8368
TOP1	-7160	8404
HSPA8	-7307	8180
PSMC6	-6851	8666
UBB	-7104	8341
CANX	-6936	8532
CAPZA1	-6942	8474
DNAJC3	-7149	8179
USO1	-6682	8749
PSME4	-6830	8511
UBE2E1	-6831	8405
SKP1	-6803	8394
PDIA3	-7283	7821
SUMO3	-7259	7825
PSMD1	-6497	8619
C1GALT1C1	-6956	8035
SEL1L	-7264	7670
RAB6A	-6370	8664
HDAC2	-6396	8620

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
A4GNT	4195.0	1243.0
AAAS	5561.0	-2261.0
ACTB	-4152.0	7953.0
ACTL6A	523.0	2819.0
ACTR10	268.0	6666.0
ACTR1A	965.0	5035.0
ACTR5	5649.0	-5977.0
ACTR8	480.0	-4636.0
ADAM10	-6444.0	8149.0
ADAMTS1	-5452.0	8739.0
ADAMTS10	4075.0	-5365.0
ADAMTS12	3513.0	5824.0
ADAMTS13	676.0	3925.0
ADAMTS14	3645.0	-1429.0
ADAMTS15	-1865.0	-5976.0
ADAMTS16	6061.0	-5109.0
ADAMTS17	898.0	-2086.0
ADAMTS18	5565.0	-5223.0
ADAMTS19	-1084.0	3439.0
ADAMTS2	-2074.0	8088.0
ADAMTS3	5455.0	1208.0
ADAMTS4	-4558.0	7178.0
ADAMTS5	4732.0	6838.0
ADAMTS6	3714.0	2516.0
ADAMTS7	-3098.0	6102.0
ADAMTS8	3341.0	380.0
ADAMTS9	-4215.0	5871.0
ADAMTSL1	7394.0	7561.0
ADAMTSL2	1075.0	7367.0
ADAMTSL3	8145.0	-5509.0
ADAMTSL4	4218.0	4581.0
ADAMTSL5	4696.0	588.0
ADRB2	-6910.0	4340.0
ADRM1	-6170.0	-477.0
AFP	7002.0	840.0
AGBL2	843.0	-1917.0
AGBL3	-1381.0	22.0
AGBL4	4738.0	-1532.0
AGBL5	1997.0	-5951.0
AGTPBP1	-5932.0	5839.0
ALB	6253.0	-380.0
ALG1	-2121.0	-4072.0
ALG10	-206.5	4755.5
ALG10B	-206.5	4755.5
ALG11	-1679.0	4323.0
ALG12	-3609.0	1483.0
ALG14	-5434.0	4618.0
ALG2	-6555.0	5827.0
ALG3	-509.0	-3892.0
ALG5	-3605.0	-1803.0
ALG6	706.0	-1870.0
ALG8	-6352.0	1201.0
ALG9	-2677.5	-938.5
ALPL	7672.0	1079.0
AMDHD2	-5012.5	-6718.5
AMELX	-2293.0	58.0
AMFR	6669.0	-1047.0
ANK1	-2384.0	4523.0
ANK2	6760.0	923.0
ANK3	-300.0	4794.0
ANKRD28	8017.0	7539.0
ANKRD9	7272.0	-4117.0
ANO8	7350.0	-5683.0
APC	4716.0	8376.0
APLP2	6384.0	6357.0
APOA1	3682.0	-305.0
APOA2	5921.0	5590.0
APOB	7604.0	5782.0
APOE	5835.0	342.0
APOL1	-5660.5	2701.5
APP	-5115.0	6758.0
AR	2841.0	2349.0
ARCN1	-6138.0	8768.0
ARF1	-5273.0	7470.0
ARF3	4831.5	-5103.5
ARF4	-6276.0	6071.0
ARF5	5403.0	222.0
ARFGAP1	-1727.0	-5894.0
ARFGAP2	5632.0	-3320.0
ARFGAP3	-1901.0	5934.0
ARRB1	-6250.0	3030.0
ARRB2	-3644.0	681.0
ARSA	4080.0	-2367.0
ARSB	-5231.0	2994.0
ARSG	-6486.0	-3133.0
ARSI	-5854.0	1182.0
ARSJ	-4150.0	1548.0
ARSK	-3950.0	5751.0
ART3	4663.0	4318.0
ART4	4588.0	8588.0
ASB1	5747.0	-5391.0
ASB11	8005.0	3354.0
ASB13	-4592.0	5233.0
ASB14	4009.0	1161.0
ASB15	2791.0	-2241.0
ASB16	-285.0	-261.0
ASB18	-1279.0	-1197.0
ASB2	-4035.0	3690.0
ASB3	-3110.0	1156.0
ASB4	2909.0	2350.0
ASB5	1025.0	-247.0
ASB6	2948.0	-2420.0
ASB7	4873.0	2631.0
ASB8	-2617.0	6851.0
ASB9	-6461.0	6880.0
ASGR1	4230.0	-1124.0
ASXL1	6731.0	-1061.0
ASXL2	2377.0	3074.0
ATXN3	633.5	4150.5
ATXN3L	633.5	4150.5
ATXN7	-353.0	-389.0
AURKA	514.0	6578.0
AURKB	4296.0	-837.0
AXIN1	2211.0	-3480.0
AXIN2	6079.0	1221.0
B3GALNT2	-6999.0	-4423.0
B3GLCT	2664.0	5363.0
B3GNT2	830.0	-6274.0
B3GNT3	-3777.0	7172.0
B3GNT4	1421.0	-968.0
B3GNT5	-1379.0	2480.0
B3GNT7	6328.0	-3498.0
B3GNT8	2914.0	-5528.0
B3GNT9	-141.0	2484.0
B3GNTL1	4655.0	-4657.0
B4GALT1	-356.0	-3621.0
B4GALT2	6215.0	627.0
B4GALT3	-1790.0	-3235.0
B4GALT4	6095.0	4039.0
B4GALT5	-7316.0	-2072.0
B4GALT6	-2315.0	8205.0
B4GAT1	7224.0	-6185.0
BABAM1	-4088.5	3864.5
BAP1	891.0	3290.0
BARD1	16.0	-4000.0
BCL10	-3598.0	5942.0
BET1L	2662.0	-5180.0
BGLAP	-4940.0	-647.0
BIRC2	-4230.0	3665.0
BIRC3	6091.0	6158.0
BIRC5	-3018.0	-2773.0
BLM	6861.0	5650.0
BMI1	-4453.5	8309.5
BMP15	6174.0	5215.0
BMP4	6672.0	7143.0
BRCA1	-2450.0	4279.0
BRCC3	-3707.0	8439.0
BST1	5884.0	6856.0
BTBD1	-5007.0	8727.0
BTBD6	2905.0	-1931.0
BTRC	3218.0	-5334.0
C1GALT1	-6844.0	7463.0
C1GALT1C1	-6956.0	8035.0
C3	7675.0	3404.0
C4A	-311.5	-5183.5
CALM1	-4401.0	8702.0
CALR	-7105.0	5809.0
CALU	-3535.0	8715.0
CAMKMT	-1114.0	1751.0
CAND1	-6336.0	3476.0
CANX	-6936.0	8532.0
CAPZA1	-6942.0	8474.0
CAPZA2	-1687.0	8135.0
CAPZB	-2513.0	7203.0
CASP8AP2	-4218.0	7406.0
CBX2	1808.0	-1479.0
CBX4	3352.0	-2144.0
CBX5	-2253.0	4533.0
CBX8	-2773.0	176.0
CCDC22	-4166.0	-3221.0
CCDC8	500.0	-661.0
CCNA2	4669.0	307.0
CCNF	4264.0	-2470.0
CCP110	1823.0	739.0
CD109	-5918.0	1745.0
CD52	-3982.0	3448.0
CD55	-6863.0	6749.0
CD59	5509.5	-1796.5
CDC20	6493.0	-3052.0
CDC25A	-5099.0	1807.0
CDC34	-806.0	2346.0
CDC73	-5482.0	8489.0
CDCA8	432.0	464.0
CDH2	-7013.0	-2104.0
CDK1	3873.0	2662.0
CEACAM5	3793.5	5357.5
CEACAM7	3793.5	5357.5
CETN2	-5912.0	7106.0
CFP	-3458.0	-5006.0
CFTR	-6902.0	4865.0
CHD3	-7230.0	-2465.0
CHM	-4490.0	8464.0
CHML	1162.0	5630.0
CHRDL1	-3595.0	4763.0
CHST10	-5839.0	-580.0
CHST8	6306.0	3826.0
CISH	-419.0	-2121.0
CKAP4	4629.0	6520.0
CLSPN	3534.0	-3857.0
CMAS	-4436.0	2723.0
CNIH1	-3991.0	8144.0
CNIH2	-2187.0	-4202.0
CNIH3	282.0	-4450.0
CNTN3	1496.0	-2111.0
CNTN4	3084.0	-2922.0
CNTN5	-5428.0	-587.0
COG1	6605.0	-5589.0
COG2	549.0	4121.0
COG3	-5097.0	5605.0
COG4	1502.0	-5457.0
COG5	-2281.0	6788.0
COG6	-4517.0	730.0
COG7	6910.0	3017.0
COMMD1	-915.0	8837.0
COMMD10	4464.0	3207.0
COMMD2	1346.0	4984.0
COMMD3	-4289.0	8822.0
COMMD4	4990.0	-4771.0
COMMD5	-2686.0	-4351.0
COMMD6	-4712.0	-68.0
COMMD7	-5073.5	1534.5
COMMD8	-5016.0	752.0
COMMD9	-1892.0	-1552.0
COPA	488.0	2943.0
COPB1	-2848.0	7946.0
COPB2	-4259.0	8427.0
COPE	1600.0	4567.0
COPG1	-3891.0	3599.0
COPG2	2511.0	4641.0
COPS2	-5385.0	8716.0
COPS3	-904.0	8468.0
COPS4	-2811.0	8111.0
COPS5	430.0	6558.0
COPS6	1528.0	28.0
COPS7A	5878.0	-2436.0
COPS7B	-2394.0	-5916.0
COPS8	-147.0	1724.0
COPZ1	-4248.0	-67.0
COPZ2	3609.0	1137.0
CP	7736.0	7894.0
CPM	157.0	8264.0
CREBBP	-6181.0	3954.0
CSF1	-2451.0	7450.0
CSNK1D	-1602.0	2506.0
CST3	2605.0	4686.0
CTBP1	2741.0	-5332.0
CTR9	-6522.0	7934.0
CTSA	6070.0	1611.0
CTSC	-1974.0	7696.0
CTSZ	-2861.0	2478.0
CUL1	-2997.0	6875.0
CUL2	-6236.0	8506.0
CUL3	-3105.0	8488.0
CUL4A	1695.0	4740.0
CUL4B	-3340.0	8151.0
CUL5	-5371.0	8605.0
CUL7	7850.0	-5060.0
CUL9	5310.0	-5966.0
CYLD	-4935.0	4060.0
DAD1	-601.0	-4283.0
DAG1	6646.0	3480.0
DAXX	-867.0	1599.0
DCAF10	-6404.0	7363.0
DCAF11	2933.5	98.5
DCAF13	-6109.0	5418.0
DCAF17	-5679.0	335.0
DCAF4	6054.5	-1359.5
DCAF5	5719.0	1049.0
DCAF6	4193.0	4461.0
DCAF7	3398.0	-1866.0
DCAF8	32.0	-4825.0
DCTN1	7218.0	-3098.0
DCTN2	2623.0	-2017.0
DCTN3	-715.0	689.0
DCTN4	-4133.0	7527.0
DCTN5	-4033.0	5094.0
DCTN6	4374.0	7565.0
DCUN1D1	-5365.0	8421.0
DCUN1D2	-5235.0	979.0
DCUN1D3	-4742.0	2345.0
DCUN1D4	-1794.0	4516.0
DCUN1D5	-4561.0	3411.0
DDA1	4498.0	1487.0
DDB1	7351.0	4675.0
DDB2	7194.0	-3157.0
DDOST	-5017.0	2674.0
DDX17	-6389.0	-6574.0
DDX5	-3313.0	-2478.0
DDX58	7214.0	-485.0
DERL1	-5101.0	3639.0
DERL2	-7153.0	6854.0
DHDDS	-4632.0	-1973.0
DHPS	5170.0	-5001.0
DMP1	693.0	1827.0
DNAJC24	-3232.0	1312.0
DNAJC3	-7149.0	8179.0
DNMT1	-576.0	893.0
DNMT3A	-3125.0	-5315.0
DNMT3B	443.0	-468.0
DOHH	5309.0	-5875.0
DOLK	-1597.0	-6134.0
DOLPP1	4713.0	-4095.0
DPAGT1	-4124.0	-3201.0
DPH1	6675.0	-6022.0
DPH2	1888.0	-3053.0
DPH3	-1215.0	8198.0
DPH5	1726.0	-2410.0
DPH6	1352.0	7061.0
DPH7	6874.0	-3787.0
DPM1	4121.0	435.0
DPM2	4055.0	2348.0
DPM3	-20.0	-5789.0
DTL	254.0	990.0
DYNC1H1	4822.0	2594.0
DYNC1I1	3045.0	-5230.0
DYNC1I2	-251.0	7398.0
DYNC1LI1	2249.0	7292.0
DYNC1LI2	-1436.0	1861.0
DYNLL1	-6952.0	7645.0
DYNLL2	4932.0	-5028.0
EDEM1	-7256.0	285.0
EDEM2	-3522.0	-3508.0
EDEM3	-6042.0	5002.0
EEF2	-3312.0	2063.0
EEF2KMT	4275.0	-1189.0
EID3	-1519.0	-3324.0
EIF5A	2123.5	2213.5
EIF5A2	170.0	5525.0
ELOB	6643.0	3269.0
ELOC	-3325.0	7837.0
ENGASE	7650.0	-6005.0
EP300	-2449.0	1336.0
EPAS1	6886.0	8502.0
ERCC8	-1160.0	1435.0
ESR1	-187.0	-1356.0
ETFB	5896.0	-2345.0
ETFBKMT	-1995.0	-1578.0
EVA1A	6345.0	-2797.0
F10	7628.0	-1082.0
F2	-3087.0	4699.0
F5	-5716.0	-1378.0
F7	2284.0	-3692.0
F8	-688.0	7499.0
FAM20A	4604.0	5067.0
FAM20C	-6640.0	-3728.0
FBN1	6578.0	8391.0
FBXL12	6303.0	-6457.0
FBXL13	1597.0	-4376.0
FBXL14	3254.0	-5925.0
FBXL15	4607.0	-4358.0
FBXL16	4642.0	451.0
FBXL18	3324.0	-4163.0
FBXL19	-1608.0	-4038.0
FBXL20	3692.0	-5654.0
FBXL22	5538.0	-6092.0
FBXL3	-5113.0	5030.0
FBXL4	3694.0	2851.0
FBXL5	-5339.0	1379.0
FBXL7	-3047.0	1531.0
FBXL8	1855.5	-6099.5
FBXO10	-2534.0	-4069.0
FBXO11	-2703.0	8171.0
FBXO15	-1975.0	2890.0
FBXO17	3510.0	-1954.0
FBXO2	4620.0	4693.0
FBXO21	8209.0	-5962.0
FBXO22	-6695.0	4983.0
FBXO27	-2654.0	1841.0
FBXO30	-5216.0	5730.0
FBXO31	5477.0	-4217.0
FBXO32	7523.0	2250.0
FBXO4	-5534.0	5796.0
FBXO40	-4210.0	4616.0
FBXO6	7480.0	1442.0
FBXO7	-6524.0	-2660.0
FBXO9	-3297.0	-3812.0
FBXW10	-457.0	-3065.0
FBXW11	-3788.0	3125.0
FBXW12	858.0	-1111.0
FBXW2	2426.0	1249.0
FBXW4	6455.0	-3779.0
FBXW5	6633.0	-4037.0
FBXW7	-1739.0	4510.0
FBXW8	7356.0	-1698.0
FBXW9	7633.0	-5232.0
FCGR3B	-5407.5	6212.5
FCSK	7695.0	-6539.0
FEM1A	-503.0	-4374.0
FEM1B	-180.0	4328.0
FEM1C	-3374.0	4793.0
FGA	4508.0	5893.0
FGG	5980.0	5427.0
FKBP8	1589.0	-3343.0
FN1	7489.0	8379.0
FN3K	-3679.0	-6554.0
FN3KRP	798.0	-502.0
FOLR1	-6908.0	-283.0
FOLR2	4808.5	-5490.5
FOXK1	3482.0	-6464.0
FOXK2	-5706.0	1999.0
FOXO4	257.0	-4431.0
FPGT	-6295.0	6525.0
FSTL1	4528.0	8707.0
FSTL3	7808.0	-4121.0
FUCA1	-2319.0	5869.0
FUCA2	-6780.0	1532.0
FUOM	4551.0	-917.0
FURIN	3696.0	-3590.0
FUT8	-5026.0	4575.0
GALNT1	-6827.0	6806.0
GALNT10	2250.0	7699.0
GALNT11	-38.0	-3955.0
GALNT12	6172.0	-2979.0
GALNT13	-1133.0	-4324.0
GALNT14	-7194.0	-1930.0
GALNT15	6847.0	5369.0
GALNT16	1150.0	-4717.0
GALNT17	-5790.0	5548.0
GALNT18	-4976.0	1906.0
GALNT2	-4331.0	2581.0
GALNT3	-6728.0	6831.0
GALNT4	4213.5	-1901.5
GALNT6	538.0	-3543.0
GALNT7	-5139.0	1034.0
GALNT9	3166.0	-4823.0
GALNTL6	1986.0	-5583.0
GAN	7738.0	-2732.0
GANAB	-6749.0	-2365.0
GAS6	7430.0	-2362.0
GATA3	7885.0	-1653.0
GBF1	-6681.0	3356.0
GCNT1	-6421.0	-331.0
GCNT3	4031.0	-5990.0
GCNT4	7870.0	5943.0
GCNT7	4911.0	-6391.0
GFPT1	-5236.0	4132.0
GFPT2	1399.0	5662.0
GGCX	-6750.0	-4579.0
GLB1	-5376.0	2645.0
GMDS	3172.0	2992.0
GMPPA	-3878.0	-1263.0
GMPPB	-3902.0	-4795.0
GNE	5717.0	4001.0
GNPNAT1	66.0	8335.0
GOLGB1	-4541.0	3630.0
GOLM1	7444.0	4859.0
GORASP1	1404.0	-5586.0
GOSR1	2520.0	5197.0
GOSR2	-4613.5	7118.5
GP2	-1211.0	-3807.0
GPAA1	696.0	-5319.0
GPC3	-3602.0	6611.0
GPIHBP1	4244.0	8224.0
GPLD1	1497.0	-753.0
GPS1	-1275.0	3233.0
GRIA1	3840.0	-983.0
H2AC20	7413.0	2470.0
H2AC21	6478.0	633.0
H2AW	-5259.0	4003.0
H2BC11	3900.0	-3127.0
H2BC14	1703.0	1613.0
H2BC18	4839.0	6098.0
H2BC5	3445.0	-761.0
HCFC1	-1575.0	1730.0
HDAC1	-3050.0	4701.0
HDAC2	-6396.0	8620.0
HDAC4	3270.0	-868.0
HDAC7	5870.0	-2839.0
HERC2	-123.0	-4460.0
HGS	-1920.0	704.0
HIC1	1899.0	3532.0
HIF1A	7374.0	8562.0
HIF3A	5098.0	-246.0
HIPK2	-2011.0	3610.0
HLTF	-7039.0	7617.0
HNRNPC	-7051.0	8787.0
HNRNPK	-808.0	7246.0
HRC	276.0	-2090.0
HSP90B1	-7279.0	8368.0
HSPA8	-7307.0	8180.0
ICMT	-315.0	-1207.0
IDE	-1263.0	3492.0
IFIH1	-1353.0	5986.0
IGFBP1	4095.0	5747.0
IGFBP3	2259.0	8596.0
IGFBP4	-3451.0	-5136.0
IGFBP5	-3193.0	3366.0
IGFBP7	-655.0	-4154.0
IKBKE	2587.0	-6365.0
IKBKG	3700.0	-677.0
IL33	7328.0	7911.0
INCENP	-473.0	3252.0
ING2	-3962.0	7754.0
INO80	4038.0	3998.0
INO80B	6545.5	-3302.5
INO80C	4335.0	3546.0
INO80D	-6575.0	6230.0
INO80E	-899.0	1705.0
ITIH2	-3802.0	562.0
JOSD1	-6550.0	274.0
JOSD2	-6887.0	-5777.0
KAT2A	-3442.0	-2675.0
KAT2B	-5780.0	6796.0
KBTBD13	2313.0	2189.0
KBTBD6	-6874.5	7477.5
KBTBD7	-6874.5	7477.5
KBTBD8	-2145.0	-505.0
KCTD6	5371.0	1842.0
KCTD7	3938.0	-338.0
KDELR1	-5082.0	-3141.0
KDELR2	-4969.0	8520.0
KDELR3	3008.0	2539.0
KDM1B	-5262.0	5818.0
KEAP1	-3703.0	-3144.0
KIN	1226.0	3114.0
KLHL11	4250.0	3553.0
KLHL13	-3686.0	6045.0
KLHL2	-6669.0	8214.0
KLHL20	-3947.0	1875.0
KLHL21	7522.0	-6646.0
KLHL22	-810.5	-5052.5
KLHL25	823.0	-4743.0
KLHL3	6109.0	2377.0
KLHL41	5118.0	-6151.0
KLHL42	-111.0	-2648.0
KLHL5	4270.0	3505.0
KLHL9	-5268.0	6137.0
KNG1	7980.0	7099.0
KTN1	8011.0	6420.0
L3MBTL2	4709.0	-804.0
LAMB1	1484.0	-2565.0
LAMB2	7370.0	6700.0
LAMC1	7625.0	6528.0
LARGE1	1668.0	1564.0
LARGE2	7616.0	-196.0
LEO1	-7109.0	5081.0
LGALS1	5562.0	3929.0
LMAN1	-4772.0	8101.0
LMAN2	-6960.0	209.0
LMAN2L	-6950.0	-4458.0
LMO7	6730.0	-2505.0
LRRC41	907.0	-3596.0
LRRC49	6677.0	-1028.0
LSAMP	3143.0	-1218.0
LTBP1	-5412.0	7176.0
LY6D	-5266.0	-2235.0
LY6E	-7355.0	5208.0
LY6G6C	4541.0	-5396.0
LY6G6D	4861.0	-2442.0
LY6H	2837.0	-6470.0
LYPD1	-1870.0	744.0
LYPD5	-2471.0	-1799.0
LYPD6B	250.0	6073.0
MAGT1	-6822.0	7703.0
MAN1A1	-4332.0	3367.0
MAN1A2	-1067.0	6604.0
MAN1B1	-1873.0	-6055.0
MAN1C1	6879.0	7174.0
MAN2A1	8162.0	5453.0
MAN2A2	-1276.0	3170.0
MANEA	6645.0	7410.0
MAP3K7	1594.0	7480.0
MARCHF6	3309.0	-3001.0
MAT2B	4842.0	-1317.0
MAVS	6937.0	-2375.0
MBD1	-29.0	2332.0
MBD5	-1298.0	-5280.0
MBD6	2343.0	-6676.0
MBTPS1	-6525.0	-4354.0
MCFD2	-4954.0	6881.0
MCRS1	3404.0	504.0
MDC1	2939.0	-2511.0
MDGA1	-2378.0	-2911.0
MDGA2	-773.0	-2625.0
MDM2	5569.0	7967.0
MDM4	-2223.0	-5305.0
MELTF	-15.0	-1729.0
MEN1	-1596.0	-513.0
METTL21A	1969.0	-2314.0
METTL22	7110.0	-3618.0
MFGE8	7259.0	7979.0
MGAT1	-2205.0	-4578.0
MGAT2	-4100.0	4842.0
MGAT3	-6706.0	-3427.0
MGAT4A	8028.0	2426.0
MGAT4B	6084.0	-4137.0
MGAT4C	6273.0	-4542.0
MGAT5	-6087.0	2955.0
MIA2	-5486.0	8570.0
MITF	4134.0	-1967.0
MLEC	-7059.0	-620.0
MOGS	-7081.0	-6077.0
MPDU1	3608.0	-2985.0
MPI	-1157.0	6001.0
MRTFA	-4911.0	-662.0
MSLN	-1618.0	3678.0
MTA1	-1428.0	-2770.0
MUC1	7970.0	3179.0
MUC13	3695.0	1168.0
MUC19	-1591.0	-6413.0
MUC20	3931.0	5255.0
MUC3A	4383.0	638.0
MUC4	-846.0	-343.0
MUC5B	1330.0	-4558.0
MUC6	3660.0	-6706.0
MUL1	6223.0	-5611.0
MVD	-6321.0	-3670.0
MXRA8	-35.0	8623.0
MYC	1892.0	3123.0
MYSM1	2209.0	5254.0
NAE1	-3040.0	7552.0
NAGK	-4604.0	-6000.0
NANP	6116.0	213.0
NANS	-6265.0	4736.0
NAPA	5425.0	1632.0
NAPB	2953.0	-4029.0
NAPG	3323.0	2180.0
NCOA1	-3434.0	7005.0
NCOA2	-5757.0	5994.0
NCOR2	-225.0	-3484.0
NDC1	6665.0	-1084.0
NEDD8	-4578.0	7681.0
NEGR1	605.0	6193.0
NEU1	-4896.0	-6581.0
NEU2	-5135.0	4638.0
NEU3	5534.0	4644.0
NEURL2	6233.0	-6698.0
NFKB2	2120.0	-4751.0
NFKBIA	1631.0	4830.0
NFRKB	6706.0	-4434.0
NGLY1	-6176.0	6210.0
NICN1	6266.5	2603.5
NLRP3	-5337.0	1863.0
NOD1	5283.0	4068.0
NOD2	-6286.0	2681.0
NOP58	-4438.0	5964.0
NOTUM	-4518.0	-4347.0
NPL	7879.0	2302.0
NR1H2	3611.0	-4559.0
NR1H3	-6285.0	1226.0
NR1H4	6851.0	5380.0
NR1I2	2434.0	-4905.0
NR2C1	-431.0	2786.0
NR3C1	-2732.0	2240.0
NR3C2	7008.0	-3900.0
NR4A2	-168.0	5972.0
NR5A2	-2631.0	-1601.0
NRIP1	-4907.0	6136.0
NRN1	2297.0	1476.0
NSF	4215.0	7420.0
NSMCE1	6895.0	-3356.0
NSMCE2	5776.0	-3866.0
NSMCE3	2746.0	-3003.0
NSMCE4A	5303.0	6438.0
NTM	3762.0	317.0
NTNG1	-6397.0	4061.0
NTNG2	4666.0	-4040.0
NUB1	7499.0	664.0
NUCB1	-4766.0	6164.0
NUDT14	1773.0	5977.0
NUP107	3423.0	7169.0
NUP133	2759.0	-4113.0
NUP153	-4638.0	7763.0
NUP155	6347.0	2192.0
NUP160	-5230.0	1753.0
NUP188	3880.0	-4145.0
NUP205	855.0	6303.0
NUP210	8193.0	-4172.0
NUP214	7802.0	-5326.0
NUP35	-4374.0	-921.0
NUP37	3596.0	1004.0
NUP42	4998.0	-596.0
NUP43	-2270.0	3764.0
NUP50	-4961.0	641.0
NUP54	-3355.0	6010.0
NUP58	2230.0	7116.0
NUP62	4963.0	-4765.0
NUP85	1103.0	-4750.0
NUP88	4817.0	4002.0
NUP93	5331.0	6196.0
NUP98	-2590.0	5122.0
NUS1	-3128.0	2669.0
OBSL1	-2821.0	4269.0
OGT	-4547.0	-6169.0
OPCML	-1744.0	-2172.0
OS9	-5615.0	3279.0
OTOA	1547.0	-1720.0
OTUB1	3275.0	3588.0
OTUB2	-4667.0	-3379.0
OTUD3	-2182.0	-768.0
OTUD5	-963.0	-1531.0
OTUD7A	-562.0	1361.0
OTUD7B	3158.0	927.0
OTULIN	-2347.0	4384.0
P4HB	-6743.0	5398.0
PAF1	799.0	4723.0
PARK7	-4866.0	231.0
PARP1	134.0	473.0
PCGF2	6981.0	-1609.0
PCNA	5956.0	8353.0
PCSK9	38.0	1779.0
PDIA3	-7283.0	7821.0
PDIA6	-7267.0	3608.0
PENK	3856.0	1044.0
PEX10	4740.0	-3790.0
PEX12	3372.0	1451.0
PEX13	-1588.0	5391.0
PEX14	5317.0	5271.0
PEX2	-6638.0	5954.0
PEX5	4872.0	-5747.0
PGAP1	3191.0	1054.0
PGM3	-5155.0	-58.0
PGR	-4247.0	5891.0
PHC1	-3375.0	-2631.0
PHC2	4373.0	-2023.0
PHC3	-3667.0	-4511.0
PIAS1	3194.0	2440.0
PIAS2	-551.0	4275.0
PIAS3	5881.0	-5095.0
PIAS4	1983.0	-5993.0
PIGA	5537.0	-3293.0
PIGB	-2545.0	-3897.0
PIGC	-712.0	-1136.0
PIGF	-358.0	4560.0
PIGG	481.0	5219.0
PIGH	-4713.0	4084.0
PIGK	-5555.0	7969.0
PIGL	2370.0	-566.0
PIGM	6207.0	-1731.0
PIGN	-3685.0	-6029.0
PIGO	2497.0	-6067.0
PIGP	-982.0	4138.0
PIGQ	-2789.0	-1693.0
PIGS	7634.0	-6215.0
PIGT	2201.0	-3364.0
PIGU	-128.0	-4230.0
PIGV	-5167.0	-5907.0
PIGW	3382.0	-3016.0
PIGX	-1642.0	7181.0
PIGY	6362.0	-5350.0
PLAUR	4004.0	6827.0
PLET1	2119.0	3517.0
PML	6152.0	-5597.0
PMM1	7751.0	-3527.0
PMM2	-447.0	-333.0
PNPLA2	7942.0	833.0
POFUT2	2819.0	2567.0
POLB	-5395.0	7452.0
POM121	3732.5	-6552.5
POM121C	3732.5	-6552.5
POMGNT1	-1550.0	1400.0
POMGNT2	-477.0	-4638.0
POMK	-3654.0	738.0
POMT1	5670.0	-6064.0
POMT2	-591.0	-5247.0
PPARA	7841.0	-6419.0
PPARG	-3636.0	5654.0
PPARGC1A	7867.0	2494.0
PPP6C	1874.0	5889.0
PPP6R1	-4706.0	-2647.0
PPP6R3	-5114.0	7597.0
PREB	-6991.0	-1923.0
PRKCSH	-4469.0	-2597.0
PRKDC	-5092.0	3381.0
PRMT3	1957.0	-2306.0
PRND	1920.0	1499.0
PROS1	4907.0	7279.0
PROZ	-386.0	-4681.0
PRSS23	-4729.0	8268.0
PSCA	3876.0	-2120.0
PSMA1	-6705.0	7838.0
PSMA2	-5464.5	6058.5
PSMA3	-3145.0	7801.0
PSMA4	-6074.0	4688.0
PSMA5	-6660.0	4497.0
PSMA6	-1954.0	8445.0
PSMA7	1612.0	7052.0
PSMA8	649.0	-4004.0
PSMB1	-5281.0	5936.0
PSMB10	3752.0	-908.0
PSMB11	1977.0	-5501.0
PSMB2	1472.0	-4144.0
PSMB3	-3388.0	5539.0
PSMB4	-4941.0	-5852.0
PSMB5	-1638.0	-2409.0
PSMB6	1806.0	-1845.0
PSMB7	-4628.0	-657.0
PSMB8	1080.0	-3793.0
PSMB9	5987.0	-4708.0
PSMC1	-1312.0	4327.0
PSMC2	-6765.0	4648.0
PSMC3	-4285.0	3386.0
PSMC4	-6423.0	7920.0
PSMC5	-4831.0	1120.0
PSMC6	-6851.0	8666.0
PSMD1	-6497.0	8619.0
PSMD10	-1613.0	2576.0
PSMD11	-6873.0	5201.0
PSMD12	-6149.0	8628.0
PSMD13	1898.0	5044.0
PSMD14	-6080.0	8262.0
PSMD2	-6702.0	-3836.0
PSMD3	-2532.0	-3242.0
PSMD4	-5648.0	4994.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
PSMD7	-6943.0	7625.0
PSMD8	1978.0	7546.0
PSMD9	7707.5	-894.5
PSME1	2907.0	5905.0
PSME2	1270.0	-4595.0
PSME3	752.0	7366.0
PSME4	-6830.0	8511.0
PSMF1	5087.0	4771.0
PTEN	-5726.0	8365.0
PTP4A2	3118.0	8121.0
PTRH2	-3116.0	273.0
PUM2	-6583.0	5351.0
QSOX1	7456.0	1100.0
RAB10	-5609.0	8060.0
RAB11A	-3713.0	8250.0
RAB11B	4309.0	4748.0
RAB12	-1057.0	8176.0
RAB13	3302.5	1698.5
RAB14	-4203.0	5569.0
RAB15	6826.0	4509.0
RAB17	90.0	2004.0
RAB18	-6358.0	6912.0
RAB19	5789.0	4435.0
RAB1A	-6571.0	7889.0
RAB1B	-80.0	-4574.0
RAB20	-4394.0	-3245.0
RAB21	-2903.0	7574.0
RAB22A	-5590.0	-1302.0
RAB23	6909.0	-2600.0
RAB24	4481.0	-5649.0
RAB25	7178.0	-2991.0
RAB26	1891.0	-3294.0
RAB27A	7997.0	1512.0
RAB27B	-4838.0	5533.0
RAB29	-3337.0	4447.0
RAB2A	-5653.0	7957.0
RAB2B	408.0	-35.0
RAB30	6435.0	5622.0
RAB31	3839.0	8541.0
RAB33B	2372.0	6149.0
RAB34	4880.0	-5413.0
RAB35	-1301.0	5850.0
RAB36	690.0	-5670.0
RAB37	1244.0	-5646.0
RAB38	-6913.0	3044.0
RAB39A	-2191.0	1676.0
RAB39B	-1021.0	6431.0
RAB3A	-21.0	-1948.0
RAB3B	5566.0	5918.0
RAB3C	-3904.0	2697.0
RAB3D	6472.0	4535.0
RAB40B	4958.0	-829.0
RAB40C	6115.0	-5991.0
RAB42	5558.0	-6373.0
RAB43	8116.0	1573.0
RAB4A	-4186.0	1766.0
RAB4B	6400.5	-1765.5
RAB5A	1537.0	7332.0
RAB5B	5887.0	3206.0
RAB5C	3703.0	3375.0
RAB6A	-6370.0	8664.0
RAB6B	7529.0	1278.0
RAB7A	-5898.0	8083.0
RAB7B	-5496.0	5451.0
RAB8A	-855.0	2596.0
RAB8B	3129.0	7133.0
RAB9A	-412.0	7818.0
RABGGTA	-4457.0	-3560.0
RABGGTB	-3446.0	2196.0
RAD18	7614.0	6266.0
RAD21	-2278.0	8063.0
RAD23A	-5824.0	-2416.0
RAD23B	-6778.0	7740.0
RAD52	708.0	-2726.0
RAE1	3041.0	-1934.0
RAET1G	-5737.0	-420.0
RAET1L	-5737.0	-420.0
RANBP2	-4575.0	8132.0
RANGAP1	-2328.0	-1549.0
RARA	183.0	-5463.0
RBBP5	-4912.0	-38.0
RBBP7	2154.0	6750.0
RBX1	-391.0	3201.0
RCE1	-2692.0	59.0
RCN1	6884.5	3888.5
RECK	5456.0	4804.0
RELA	2579.0	-2368.0
RENBP	-3824.0	-6639.0
RFT1	5663.5	-3801.5
RHOA	-5203.0	7671.0
RHOT1	1355.0	8586.0
RING1	2092.0	-5540.0
RIPK1	-2977.0	5088.0
RIPK2	5953.0	6306.0
RNF103	4818.0	3457.0
RNF123	3678.0	-5288.0
RNF128	-3314.0	5251.0
RNF139	-193.0	7634.0
RNF144A	-1187.0	7409.0
RNF146	560.0	7077.0
RNF152	-5942.0	-6366.0
RNF168	-4872.0	8120.0
RNF181	-3543.0	2524.0
RNF185	2705.0	5366.0
RNF2	-3811.0	8651.0
RNF20	-4475.0	4136.0
RNF40	534.0	-5046.0
RNF5	-1555.0	-4449.0
RNF7	-2546.0	5701.0
RORA	-3317.0	3869.0
RPA1	4920.0	5750.0
RPN1	-7121.0	7464.0
RPN2	-5521.0	3974.0
RPS2	7322.0	4216.0
RPS27A	-133.0	-1807.0
RRAGA	-3310.0	5815.0
RTF1	931.0	5957.0
RTN4RL1	3899.0	1236.0
RTN4RL2	2427.0	6719.0
RUVBL1	-418.0	-738.0
RWDD3	-538.0	-1052.0
RXRA	-5143.0	1552.0
SAE1	2001.0	-2412.0
SAFB	-1933.0	-1132.0
SAR1B	-3423.0	7668.0
SATB1	-1732.0	4168.0
SATB2	-6836.0	401.0
SBSPON	-4153.0	3078.0
SCFD1	-5793.0	7896.0
SCMH1	2113.0	-1086.0
SDC2	-6850.0	7623.0
SEC13	-1432.0	3604.0
SEC16A	-1511.0	3230.0
SEC16B	8007.0	2261.0
SEC22A	3566.0	5061.0
SEC22B	-4623.0	5601.0
SEC22C	5970.0	-5637.0
SEC23A	-3552.0	8413.0
SEC23IP	-1834.0	5924.0
SEC24A	159.0	5121.0
SEC24B	-570.0	-3344.0
SEC24C	-5965.0	-1916.0
SEC24D	-6384.0	8428.0
SEC31A	835.0	-552.0
SEH1L	2204.0	6910.0
SEL1L	-7264.0	7670.0
SELENOS	-3903.0	1995.0
SEMA5A	-5557.0	182.0
SEMA5B	3538.0	-4929.0
SENP1	5353.0	4546.0
SENP2	-4849.0	3327.0
SENP5	-5403.0	5742.0
SENP8	-2416.0	-1768.0
SERPINA1	8234.0	4905.0
SERPINA10	292.0	-3155.0
SERPINC1	-5479.0	2358.0
SERPIND1	-2147.0	-4608.0
SHISA5	5496.0	-442.0
SHPRH	-931.0	1674.0
SIAH2	1504.0	-2759.0
SIN3A	4581.0	6116.0
SKP1	-6803.0	8394.0
SKP2	5738.0	-4232.0
SLC17A5	2333.0	243.0
SLC35A1	-5778.0	918.0
SLC35C1	-399.0	-4005.0
SMAD1	5880.0	5459.0
SMAD2	2671.0	7154.0
SMAD3	-1639.0	-2520.0
SMAD4	3068.0	901.0
SMAD7	-2050.0	-4957.0
SMC1A	-2764.0	6742.0
SMC3	-4007.0	8640.0
SMC5	1029.0	5161.0
SMC6	2636.0	7994.0
SMURF2	-6772.0	5752.0
SNX3	-6131.0	6439.0
SOCS2	4529.0	3280.0
SOCS3	4231.0	7185.0
SOCS5	1959.0	-4114.0
SOCS6	-3917.0	5004.0
SP3	-2425.0	6930.0
SPARCL1	5687.0	8683.0
SPON1	8083.0	8251.0
SPON2	1919.0	3082.0
SPP1	8204.0	5504.0
SPP2	4245.0	-2291.0
SPRN	-3817.0	3737.0
SPSB1	7434.0	4252.0
SPSB2	-6665.0	-4813.0
SPSB3	-6341.0	1346.0
SPSB4	-5638.0	-1459.0
SPTA1	-2878.0	4811.0
SPTAN1	7051.0	7359.0
SPTB	7834.0	-4096.0
SPTBN1	4136.0	7630.0
SPTBN2	7922.0	-2952.0
SPTBN5	4733.0	-1695.0
SRD5A3	-2854.0	4649.0
ST3GAL1	3065.0	8669.0
ST3GAL2	6089.0	121.0
ST3GAL3	-3090.0	3648.0
ST3GAL4	-1264.0	1193.0
ST3GAL5	2957.0	7714.0
ST3GAL6	774.0	7961.0
ST6GAL1	4830.0	6368.0
ST6GALNAC2	-6427.0	-3901.0
ST6GALNAC3	4083.0	6940.0
ST6GALNAC4	-365.0	4860.0
ST6GALNAC5	4795.0	4204.0
ST6GALNAC6	4180.5	5612.5
ST8SIA1	-6658.0	-1492.0
ST8SIA3	4668.0	-4083.0
ST8SIA4	-6249.0	6735.0
ST8SIA6	-7197.0	6205.0
STAG1	-4924.0	6068.0
STAG2	-3857.0	8559.0
STAM	-2360.0	4932.0
STAM2	494.0	2564.0
STAMBP	1626.0	5615.0
STAMBPL1	4161.0	6099.0
STC2	5064.0	3301.0
STT3A	-6845.0	4709.0
STX17	4886.0	-671.0
STX5	-4974.0	-4939.0
SUDS3	2620.0	2169.0
SUMF1	-6426.0	292.0
SUMO1	-4690.0	8345.0
SUMO2	-2663.5	8652.5
SUMO3	-7259.0	7825.0
SUZ12	-1028.0	8662.0
SYVN1	-7005.0	-3045.0
TAB1	7839.0	-5339.0
TADA2B	2387.0	-951.0
TADA3	-1946.0	-303.0
TAF10	-3030.0	2638.0
TAF9B	-362.0	4853.0
TBC1D20	1958.0	574.0
TDG	3401.0	6850.0
TF	6988.0	4696.0
TFAP2A	5071.0	350.0
TFAP2B	5540.0	-18.0
TFG	-5471.0	5860.0
TFPT	5935.0	1305.0
TGFA	4979.0	2380.0
TGFB1	-1851.0	6152.0
TGFBR1	-2001.0	7866.0
TGFBR2	930.0	7719.0
TGOLN2	-6334.0	4798.0
THBS1	8000.0	8780.0
THBS2	-3256.0	8633.0
THRA	-5014.0	2323.0
THRB	-6455.0	-1228.0
THSD1	7418.0	2048.0
THSD4	5121.0	4561.0
THSD7A	2585.0	6050.0
THSD7B	-3715.0	-1612.0
THY1	703.0	1982.0
TIMP1	-2454.0	3444.0
TMED10	-6147.0	6432.0
TMED2	-2351.0	6953.0
TMED3	-6313.0	3992.0
TMED7	-4902.5	7760.5
TMED9	-5309.0	-1036.0
TMEM115	1699.0	-4432.0
TMEM129	6222.0	-765.0
TMEM132A	-1425.0	1067.0
TNC	7133.0	6992.0
TNFAIP3	-151.0	2986.0
TNIP1	5757.0	-2590.0
TNIP2	7153.0	-6672.0
TNIP3	1974.0	5640.0
TNKS	7493.0	2959.0
TNKS2	-3624.0	4091.0
TOMM20	7388.0	3171.0
TOMM70	-6096.0	7854.0
TOP1	-7160.0	8404.0
TOP2A	3804.0	1969.0
TOP2B	-411.0	8373.0
TOPORS	4771.0	6078.0
TP53	2557.0	-3561.0
TP53BP1	-6540.0	-1951.0
TPGS1	1606.0	-5265.0
TPGS2	-3867.0	4211.0
TPR	-4239.0	8611.0
TPST1	-1632.0	2591.0
TPST2	5077.0	-171.0
TRAF2	3405.0	-3806.0
TRAF3	-6416.0	5442.0
TRAF6	1082.0	6626.0
TRAPPC1	-1429.0	4746.0
TRAPPC10	2000.0	2916.0
TRAPPC2	-3263.0	6403.0
TRAPPC2L	3633.0	-4527.0
TRAPPC3	593.0	5718.0
TRAPPC4	-1321.0	-410.0
TRAPPC5	-2311.0	-1472.0
TRAPPC6A	7806.0	-5370.0
TRAPPC6B	978.0	7705.0
TRAPPC9	1611.0	-4039.0
TRIM13	-4674.0	7419.0
TRIM25	-5042.0	-3205.0
TRIM27	-452.0	-3380.0
TRIM28	-1390.0	-6154.0
TRRAP	489.0	-6329.0
TSTA3	4940.0	53.0
TTL	-747.0	7210.0
TTLL1	-3190.0	3436.0
TTLL10	3707.0	-6689.0
TTLL11	7623.0	-2769.0
TTLL12	-3831.0	-493.0
TTLL13P	5732.5	-5749.5
TTLL3	-1884.5	-6510.5
TTLL4	610.0	-658.0
TTLL7	-5404.0	6410.0
TTLL9	5284.0	-1248.0
TUBA1A	-1927.0	8153.0
TUBA1B	-2891.0	7211.0
TUBA1C	-3546.0	8104.0
TUBB1	-954.0	3430.0
TUBB2A	1093.0	8351.0
TUBB2B	3491.0	6524.0
TUBB4A	-797.0	-1288.0
TUBB4B	-5222.0	8679.0
TUBB6	-3844.0	-5018.0
TULP4	-6907.0	5816.0
TUSC3	-5686.0	4758.0
UAP1	-7245.0	1255.0
UBA1	-3069.0	6814.0
UBA2	2443.0	2353.0
UBA3	-3218.0	8194.0
UBA52	7488.0	-4269.0
UBA6	-6905.0	6312.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
UBD	-4391.0	-3707.0
UBE2A	-4551.0	7336.0
UBE2B	-4389.0	7152.0
UBE2C	733.0	-1864.0
UBE2D1	5638.0	3025.0
UBE2D2	-935.0	6690.0
UBE2D3	-5084.0	8317.0
UBE2E1	-6831.0	8405.0
UBE2E3	441.0	4538.0
UBE2F	-4113.5	4926.5
UBE2G1	6022.0	6179.0
UBE2G2	-6897.0	3570.0
UBE2H	-2417.0	3799.0
UBE2I	5599.0	2810.0
UBE2J2	-1329.0	4541.0
UBE2K	-3148.0	7485.0
UBE2L3	-4226.5	5465.5
UBE2M	3424.0	2257.0
UBE2Q2	-701.0	7516.0
UBE2R2	-4372.0	2763.0
UBE2S	4549.0	-1742.0
UBE2T	-5289.0	-307.0
UBE2V2	-4079.0	8295.0
UBE2W	-2829.5	4199.5
UBE2Z	1411.0	812.0
UBXN1	1787.0	5401.0
UBXN7	873.0	2038.0
UCHL1	5914.0	7628.0
UCHL3	-5410.0	8491.0
UCHL5	539.0	3983.0
UGGT1	-6296.0	6707.0
UGGT2	3828.0	-1185.0
UHRF2	-6783.0	2893.0
UIMC1	2157.0	101.0
ULBP2	-5737.0	-420.0
UMOD	-6036.0	-707.0
USO1	-6682.0	8749.0
USP10	-1816.0	-1370.0
USP11	4108.0	-5507.0
USP12	-4059.0	3490.0
USP13	-642.0	3525.0
USP14	-6057.0	7777.0
USP15	-3586.0	8355.0
USP16	-5561.0	7667.0
USP18	-5163.5	-2484.5
USP19	-5375.0	-6205.0
USP2	7977.0	982.0
USP20	-4736.0	-5752.0
USP21	-4905.0	-5030.0
USP22	7555.0	4744.0
USP24	-1240.0	1404.0
USP25	6200.0	7993.0
USP28	5188.0	3798.0
USP3	-2289.0	-1034.0
USP30	2472.0	-4526.0
USP33	-7002.0	7120.0
USP34	-5195.0	7843.0
USP37	-2860.0	6585.0
USP4	-3801.0	1470.0
USP42	5235.0	-2774.0
USP44	-3242.0	2971.0
USP47	-4602.0	8299.0
USP48	-1480.0	-3844.0
USP49	7716.0	-102.0
USP5	2291.0	1038.0
USP7	-4172.0	7828.0
USP8	-6428.0	2267.0
USP9X	-5668.0	7709.0
VCAN	-3773.0	1454.0
VCP	-7069.0	5449.0
VCPIP1	1610.0	2928.0
VCPKMT	3998.0	-1277.0
VDAC1	6.0	6549.0
VDAC2	5362.0	3837.0
VDAC3	-6101.0	8417.0
VDR	3336.0	-653.0
VNN1	6246.0	7250.0
VWA1	-6465.0	122.0
WAC	-5426.0	8294.0
WDR20	3555.0	-4931.0
WDR48	-2737.0	3854.0
WDR5	3835.0	954.0
WDR61	2802.0	-446.0
WDTC1	-6026.0	-585.0
WFS1	7688.0	-3009.0
WRN	1837.0	6937.0
WSB1	7892.0	1113.0
WSB2	-3548.0	3725.0
XPC	7574.0	13.0
XPNPEP2	7580.0	-3778.0
XRCC4	-4715.0	7026.0
YKT6	2462.0	3655.0
YOD1	-4847.0	7078.0
YY1	-5129.0	3260.0
ZBTB16	2742.0	1122.0
ZNF131	-3173.0	8158.0
ZRANB1	6769.0	5090.0

---

---

Translation

Translation

metric	value
setSize	256
pMANOVA	4.93e-11
p.adjustMANOVA	3.4e-09
s.dist	0.263
s.diabetes	-0.0873
s.mitoG	0.248
p.diabetes	0.0165
p.mitoG	9.09e-12

Top 20 genes

Gene	diabetes	mitoG
TRAM1	-7037	8086
SSR1	-6752	8281
GSPT1	-6653	8055
RPN1	-7121	7464
SPCS2	-6962	7155
EPRS1	-5855	8062
MRPL42	-5566	8289
SSR2	-6516	6915
SSR3	-5773	7803
RPL7	-5186	8598
EIF3J	-4890	8838
RARS2	-6308	6760
EIF2S1	-4830	8741
TARS1	-5804	7206
SRP54	-4728	8835
EIF3A	-4951	8381
EIF3E	-4677	8580
FARSB	-6744	5894
SRP9	-5608	6951
EIF4E	-4500	8429

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
AARS1	-4867.0	5015.0
AARS2	-67.0	-1871.0
AIMP1	3483.0	-4465.0
AIMP2	3676.0	2367.0
APEH	328.0	-4272.0
AURKAIP1	4765.0	3868.0
CARS1	-5829.0	185.0
CARS2	-4415.0	-4360.0
CHCHD1	122.0	7555.0
DAP3	7249.0	-2522.0
DARS1	-2473.0	7683.0
DARS2	-5166.0	329.0
DDOST	-5017.0	2674.0
EARS2	-6504.0	-3209.0
EEF1B2	1782.0	477.0
EEF1D	-4117.0	717.0
EEF1E1	-2005.5	5771.5
EEF1G	-4888.0	4247.0
EEF2	-3312.0	2063.0
EIF2B1	-777.0	6812.0
EIF2B2	614.0	1522.0
EIF2B3	5470.0	2436.0
EIF2B4	98.0	1851.0
EIF2B5	2161.0	3945.0
EIF2S1	-4830.0	8741.0
EIF2S2	-3307.0	8799.0
EIF2S3	-2819.5	4900.5
EIF3A	-4951.0	8381.0
EIF3B	-286.0	3875.0
EIF3C	4964.5	4995.5
EIF3D	511.0	8172.0
EIF3E	-4677.0	8580.0
EIF3F	2793.0	1790.0
EIF3G	836.0	1475.0
EIF3H	-4343.0	8629.0
EIF3I	5694.0	2343.0
EIF3J	-4890.0	8838.0
EIF3K	4728.0	6062.0
EIF3L	5174.0	4824.0
EIF3M	-2954.0	7258.0
EIF4A1	5335.0	61.0
EIF4A2	-6848.0	-699.0
EIF4B	-4266.0	-945.0
EIF4E	-4500.0	8429.0
EIF4EBP1	4976.0	3262.0
EIF4G1	-5996.0	5731.0
EIF4H	5370.0	-98.0
EIF5	-1683.0	7276.0
EIF5B	-1780.0	8616.0
EPRS1	-5855.0	8062.0
ERAL1	2320.0	-4329.0
ETF1	-3268.0	8174.0
FARS2	-83.0	-1983.0
FARSA	-2969.0	-5485.0
FARSB	-6744.0	5894.0
FAU	6809.0	7710.0
GADD45GIP1	-3733.0	2788.0
GARS1	4295.0	8223.0
GFM1	-5522.0	6232.0
GFM2	-6515.0	123.0
GSPT1	-6653.0	8055.0
GSPT2	-1500.0	-264.0
HARS1	740.0	3109.0
HARS2	-3395.0	-2849.0
IARS1	-5409.0	3400.0
IARS2	-3392.0	319.0
KARS1	3885.0	5716.0
LARS1	7823.0	-1599.0
LARS2	6811.0	-3357.0
MARS1	-1343.0	1975.0
MARS2	-1273.0	3903.0
MRPL1	1286.0	8159.0
MRPL10	-1416.0	3188.0
MRPL11	3808.0	6016.0
MRPL12	-2913.0	4144.0
MRPL13	-2133.0	8018.0
MRPL14	5767.0	-2010.0
MRPL15	-1507.0	6146.0
MRPL16	-3432.0	6832.0
MRPL17	-3013.0	6746.0
MRPL18	-4156.0	1438.0
MRPL19	-3194.0	2428.0
MRPL2	5055.0	-5149.0
MRPL20	1293.0	4469.0
MRPL21	-799.0	2412.0
MRPL22	-5154.0	-1134.0
MRPL23	4418.5	-1265.5
MRPL24	167.0	-5286.0
MRPL27	6178.0	223.0
MRPL28	-814.0	3971.0
MRPL3	-5665.0	5800.0
MRPL30	5279.5	6918.5
MRPL32	-3800.0	8800.0
MRPL33	4456.0	7014.0
MRPL34	-2475.0	4196.0
MRPL35	-1990.0	4213.0
MRPL36	-5899.0	-1881.0
MRPL37	1624.0	-2298.0
MRPL38	-1580.0	-1874.0
MRPL39	-3794.0	7408.0
MRPL4	2533.0	-622.0
MRPL40	1526.0	8099.0
MRPL41	545.0	8072.0
MRPL42	-5566.0	8289.0
MRPL43	-3342.0	5014.0
MRPL44	-5549.0	3692.0
MRPL45	-4657.0	6949.0
MRPL46	-1481.0	2016.0
MRPL47	-173.0	6333.0
MRPL48	4560.0	-1377.0
MRPL49	-3192.0	2142.0
MRPL50	-6689.0	2066.0
MRPL51	-2846.0	4410.0
MRPL52	2165.0	-3073.0
MRPL53	2825.0	3497.0
MRPL54	5396.0	907.0
MRPL55	5095.0	1320.0
MRPL57	2949.0	3506.0
MRPL58	-1976.0	8348.0
MRPL9	-352.0	-3556.0
MRPS10	4929.0	5018.0
MRPS11	2555.0	585.0
MRPS12	-4229.0	-800.0
MRPS14	258.0	-5974.0
MRPS15	2010.0	4604.0
MRPS16	6603.0	-4108.0
MRPS17	1394.5	3322.5
MRPS18A	-1096.0	6572.0
MRPS18B	4074.0	7739.0
MRPS18C	6179.0	-533.0
MRPS2	-5787.0	3563.0
MRPS21	-3010.0	2159.0
MRPS22	-6062.0	5844.0
MRPS23	2764.0	7713.0
MRPS24	3458.0	-4271.0
MRPS25	4256.0	-52.0
MRPS26	2737.0	-3789.0
MRPS27	-2609.0	6487.0
MRPS28	1938.0	-3683.0
MRPS30	-1214.0	5020.0
MRPS31	-818.0	6947.0
MRPS33	-3942.0	3752.0
MRPS34	2549.0	1835.0
MRPS35	407.0	4566.0
MRPS36	-5930.0	3441.0
MRPS5	1465.0	6.0
MRPS6	5713.0	5000.0
MRPS7	-5350.0	4087.0
MRPS9	6568.0	2476.0
MRRF	-4590.0	6519.0
MTFMT	-3002.0	-2497.0
MTIF2	-5952.0	6049.0
MTIF3	-4042.0	3794.0
MTRF1L	-4995.0	-1737.0
N6AMT1	6423.0	2373.0
NARS1	-2358.0	7860.0
NARS2	-703.0	-3681.0
OXA1L	4609.0	-4940.0
PABPC1	-949.0	6861.0
PARS2	2925.0	-4066.0
PPA1	4412.0	6506.0
PPA2	-5134.0	6061.0
PTCD3	-2827.0	6093.0
QARS1	-2466.0	-794.0
RARS1	-4439.0	6407.0
RARS2	-6308.0	6760.0
RPL11	5748.0	1403.0
RPL12	6107.0	-5604.0
RPL13	5686.0	-3760.0
RPL14	5110.0	-1875.0
RPL18	2523.0	-625.0
RPL18A	4545.0	-3218.0
RPL19	4654.0	6782.0
RPL21	-1686.0	8463.0
RPL22	2365.0	459.0
RPL22L1	-5123.0	-6294.0
RPL23	-205.0	4253.0
RPL24	-409.0	6813.0
RPL26	3650.0	8722.0
RPL28	6714.0	4753.0
RPL29	2613.0	4628.0
RPL3	5378.0	1155.0
RPL30	4372.0	3664.0
RPL31	6732.0	-1507.0
RPL32	2989.0	8728.0
RPL34	661.0	7140.0
RPL35	5949.0	8834.0
RPL35A	-1509.0	6565.0
RPL36	7543.0	-2424.0
RPL36A	-5983.0	4837.0
RPL36AL	1793.0	-2074.0
RPL37	2109.0	-667.0
RPL38	5601.0	5675.0
RPL3L	-5986.0	4937.0
RPL4	2582.0	8471.0
RPL6	572.0	7594.0
RPL7	-5186.0	8598.0
RPL8	3526.0	820.0
RPLP2	3550.0	3555.0
RPN1	-7121.0	7464.0
RPN2	-5521.0	3974.0
RPS13	7174.0	315.0
RPS14	4070.0	4443.0
RPS15	7253.0	6174.0
RPS16	6244.0	1119.0
RPS17	5667.0	7685.0
RPS18	4253.0	-526.0
RPS19	6565.0	-1215.0
RPS2	7322.0	4216.0
RPS21	7111.0	-6494.0
RPS25	4261.0	8455.0
RPS27A	-133.0	-1807.0
RPS28	7208.0	-396.0
RPS3	2340.0	4381.0
RPS3A	-3115.0	8824.0
RPS4X	2522.0	7391.0
RPS5	3848.0	7515.0
RPS6	-1700.0	8603.0
RPS8	3874.0	7646.0
RPS9	-1719.0	-2555.0
SARS1	-2185.0	3720.0
SARS2	5893.5	-4866.5
SEC11A	-6674.0	2097.0
SEC11C	-5093.0	4777.0
SEC61A1	-6475.0	-2203.0
SEC61A2	-3708.0	-6590.0
SEC61B	-6411.0	-260.0
SEC61G	-2855.0	8720.0
SPCS1	-5914.0	4706.0
SPCS2	-6962.0	7155.0
SPCS3	4330.0	1501.0
SRP14	372.0	5948.0
SRP19	-4136.0	5550.0
SRP54	-4728.0	8835.0
SRP68	-2952.0	5498.0
SRP72	-4187.0	8263.0
SRP9	-5608.0	6951.0
SRPRA	-863.0	3844.0
SRPRB	-4529.0	4441.0
SSR1	-6752.0	8281.0
SSR2	-6516.0	6915.0
SSR3	-5773.0	7803.0
SSR4	4091.0	1326.0
TARS1	-5804.0	7206.0
TARS2	-5.0	-2575.0
TRAM1	-7037.0	8086.0
TRMT112	-6614.0	-1009.0
TSFM	-2770.0	-6449.0
TUFM	-2876.0	2310.0
UBA52	7488.0	-4269.0
VARS1	7544.0	-5251.0
VARS2	2311.0	-4975.0
WARS1	2233.0	2888.0
WARS2	-3058.0	-2683.0
YARS1	-6414.0	4044.0
YARS2	-4678.0	-2621.0

---

---

Cap-dependent Translation Initiation

Cap-dependent Translation Initiation

metric	value
setSize	85
pMANOVA	5.33e-11
p.adjustMANOVA	3.4e-09
s.dist	0.39
s.diabetes	0.173
s.mitoG	0.35
p.diabetes	0.00589
p.mitoG	2.5e-08

Top 20 genes

Gene	diabetes	mitoG
RPL35	5949.0	8834.0
FAU	6809.0	7710.0
RPS15	7253.0	6174.0
RPS17	5667.0	7685.0
RPS25	4261.0	8455.0
RPL28	6714.0	4753.0
RPL26	3650.0	8722.0
RPL38	5601.0	5675.0
RPL19	4654.0	6782.0
RPS2	7322.0	4216.0
RPS8	3874.0	7646.0
RPS5	3848.0	7515.0
EIF3K	4728.0	6062.0
RPL32	2989.0	8728.0
EIF3L	5174.0	4824.0
EIF3C	4964.5	4995.5
RPL4	2582.0	8471.0
RPS4X	2522.0	7391.0
RPS14	4070.0	4443.0
EIF4EBP1	4976.0	3262.0

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
EIF2B1	-777.0	6812.0
EIF2B2	614.0	1522.0
EIF2B3	5470.0	2436.0
EIF2B4	98.0	1851.0
EIF2B5	2161.0	3945.0
EIF2S1	-4830.0	8741.0
EIF2S2	-3307.0	8799.0
EIF2S3	-2819.5	4900.5
EIF3A	-4951.0	8381.0
EIF3B	-286.0	3875.0
EIF3C	4964.5	4995.5
EIF3D	511.0	8172.0
EIF3E	-4677.0	8580.0
EIF3F	2793.0	1790.0
EIF3G	836.0	1475.0
EIF3H	-4343.0	8629.0
EIF3I	5694.0	2343.0
EIF3J	-4890.0	8838.0
EIF3K	4728.0	6062.0
EIF3L	5174.0	4824.0
EIF3M	-2954.0	7258.0
EIF4A1	5335.0	61.0
EIF4A2	-6848.0	-699.0
EIF4B	-4266.0	-945.0
EIF4E	-4500.0	8429.0
EIF4EBP1	4976.0	3262.0
EIF4G1	-5996.0	5731.0
EIF4H	5370.0	-98.0
EIF5	-1683.0	7276.0
EIF5B	-1780.0	8616.0
FAU	6809.0	7710.0
PABPC1	-949.0	6861.0
RPL11	5748.0	1403.0
RPL12	6107.0	-5604.0
RPL13	5686.0	-3760.0
RPL14	5110.0	-1875.0
RPL18	2523.0	-625.0
RPL18A	4545.0	-3218.0
RPL19	4654.0	6782.0
RPL21	-1686.0	8463.0
RPL22	2365.0	459.0
RPL22L1	-5123.0	-6294.0
RPL23	-205.0	4253.0
RPL24	-409.0	6813.0
RPL26	3650.0	8722.0
RPL28	6714.0	4753.0
RPL29	2613.0	4628.0
RPL3	5378.0	1155.0
RPL30	4372.0	3664.0
RPL31	6732.0	-1507.0
RPL32	2989.0	8728.0
RPL34	661.0	7140.0
RPL35	5949.0	8834.0
RPL35A	-1509.0	6565.0
RPL36	7543.0	-2424.0
RPL36A	-5983.0	4837.0
RPL36AL	1793.0	-2074.0
RPL37	2109.0	-667.0
RPL38	5601.0	5675.0
RPL3L	-5986.0	4937.0
RPL4	2582.0	8471.0
RPL6	572.0	7594.0
RPL7	-5186.0	8598.0
RPL8	3526.0	820.0
RPLP2	3550.0	3555.0
RPS13	7174.0	315.0
RPS14	4070.0	4443.0
RPS15	7253.0	6174.0
RPS16	6244.0	1119.0
RPS17	5667.0	7685.0
RPS18	4253.0	-526.0
RPS19	6565.0	-1215.0
RPS2	7322.0	4216.0
RPS21	7111.0	-6494.0
RPS25	4261.0	8455.0
RPS27A	-133.0	-1807.0
RPS28	7208.0	-396.0
RPS3	2340.0	4381.0
RPS3A	-3115.0	8824.0
RPS4X	2522.0	7391.0
RPS5	3848.0	7515.0
RPS6	-1700.0	8603.0
RPS8	3874.0	7646.0
RPS9	-1719.0	-2555.0
UBA52	7488.0	-4269.0

---

---

Eukaryotic Translation Initiation

Eukaryotic Translation Initiation

metric	value
setSize	85
pMANOVA	5.33e-11
p.adjustMANOVA	3.4e-09
s.dist	0.39
s.diabetes	0.173
s.mitoG	0.35
p.diabetes	0.00589
p.mitoG	2.5e-08

Top 20 genes

Gene	diabetes	mitoG
RPL35	5949.0	8834.0
FAU	6809.0	7710.0
RPS15	7253.0	6174.0
RPS17	5667.0	7685.0
RPS25	4261.0	8455.0
RPL28	6714.0	4753.0
RPL26	3650.0	8722.0
RPL38	5601.0	5675.0
RPL19	4654.0	6782.0
RPS2	7322.0	4216.0
RPS8	3874.0	7646.0
RPS5	3848.0	7515.0
EIF3K	4728.0	6062.0
RPL32	2989.0	8728.0
EIF3L	5174.0	4824.0
EIF3C	4964.5	4995.5
RPL4	2582.0	8471.0
RPS4X	2522.0	7391.0
RPS14	4070.0	4443.0
EIF4EBP1	4976.0	3262.0

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
EIF2B1	-777.0	6812.0
EIF2B2	614.0	1522.0
EIF2B3	5470.0	2436.0
EIF2B4	98.0	1851.0
EIF2B5	2161.0	3945.0
EIF2S1	-4830.0	8741.0
EIF2S2	-3307.0	8799.0
EIF2S3	-2819.5	4900.5
EIF3A	-4951.0	8381.0
EIF3B	-286.0	3875.0
EIF3C	4964.5	4995.5
EIF3D	511.0	8172.0
EIF3E	-4677.0	8580.0
EIF3F	2793.0	1790.0
EIF3G	836.0	1475.0
EIF3H	-4343.0	8629.0
EIF3I	5694.0	2343.0
EIF3J	-4890.0	8838.0
EIF3K	4728.0	6062.0
EIF3L	5174.0	4824.0
EIF3M	-2954.0	7258.0
EIF4A1	5335.0	61.0
EIF4A2	-6848.0	-699.0
EIF4B	-4266.0	-945.0
EIF4E	-4500.0	8429.0
EIF4EBP1	4976.0	3262.0
EIF4G1	-5996.0	5731.0
EIF4H	5370.0	-98.0
EIF5	-1683.0	7276.0
EIF5B	-1780.0	8616.0
FAU	6809.0	7710.0
PABPC1	-949.0	6861.0
RPL11	5748.0	1403.0
RPL12	6107.0	-5604.0
RPL13	5686.0	-3760.0
RPL14	5110.0	-1875.0
RPL18	2523.0	-625.0
RPL18A	4545.0	-3218.0
RPL19	4654.0	6782.0
RPL21	-1686.0	8463.0
RPL22	2365.0	459.0
RPL22L1	-5123.0	-6294.0
RPL23	-205.0	4253.0
RPL24	-409.0	6813.0
RPL26	3650.0	8722.0
RPL28	6714.0	4753.0
RPL29	2613.0	4628.0
RPL3	5378.0	1155.0
RPL30	4372.0	3664.0
RPL31	6732.0	-1507.0
RPL32	2989.0	8728.0
RPL34	661.0	7140.0
RPL35	5949.0	8834.0
RPL35A	-1509.0	6565.0
RPL36	7543.0	-2424.0
RPL36A	-5983.0	4837.0
RPL36AL	1793.0	-2074.0
RPL37	2109.0	-667.0
RPL38	5601.0	5675.0
RPL3L	-5986.0	4937.0
RPL4	2582.0	8471.0
RPL6	572.0	7594.0
RPL7	-5186.0	8598.0
RPL8	3526.0	820.0
RPLP2	3550.0	3555.0
RPS13	7174.0	315.0
RPS14	4070.0	4443.0
RPS15	7253.0	6174.0
RPS16	6244.0	1119.0
RPS17	5667.0	7685.0
RPS18	4253.0	-526.0
RPS19	6565.0	-1215.0
RPS2	7322.0	4216.0
RPS21	7111.0	-6494.0
RPS25	4261.0	8455.0
RPS27A	-133.0	-1807.0
RPS28	7208.0	-396.0
RPS3	2340.0	4381.0
RPS3A	-3115.0	8824.0
RPS4X	2522.0	7391.0
RPS5	3848.0	7515.0
RPS6	-1700.0	8603.0
RPS8	3874.0	7646.0
RPS9	-1719.0	-2555.0
UBA52	7488.0	-4269.0

---

---

Formation of a pool of free 40S subunits

Formation of a pool of free 40S subunits

metric	value
setSize	67
pMANOVA	1.8e-10
p.adjustMANOVA	1.1e-08
s.dist	0.421
s.diabetes	0.261
s.mitoG	0.33
p.diabetes	0.000219
p.mitoG	2.97e-06

Top 20 genes

Gene	diabetes	mitoG
RPL35	5949.0	8834.0
FAU	6809.0	7710.0
RPS15	7253.0	6174.0
RPS17	5667.0	7685.0
RPS25	4261.0	8455.0
RPL28	6714.0	4753.0
RPL26	3650.0	8722.0
RPL38	5601.0	5675.0
RPL19	4654.0	6782.0
RPS2	7322.0	4216.0
RPS8	3874.0	7646.0
RPS5	3848.0	7515.0
EIF3K	4728.0	6062.0
RPL32	2989.0	8728.0
EIF3L	5174.0	4824.0
EIF3C	4964.5	4995.5
RPL4	2582.0	8471.0
RPS4X	2522.0	7391.0
RPS14	4070.0	4443.0
RPL30	4372.0	3664.0

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
EIF3A	-4951.0	8381.0
EIF3B	-286.0	3875.0
EIF3C	4964.5	4995.5
EIF3D	511.0	8172.0
EIF3E	-4677.0	8580.0
EIF3F	2793.0	1790.0
EIF3G	836.0	1475.0
EIF3H	-4343.0	8629.0
EIF3I	5694.0	2343.0
EIF3J	-4890.0	8838.0
EIF3K	4728.0	6062.0
EIF3L	5174.0	4824.0
EIF3M	-2954.0	7258.0
FAU	6809.0	7710.0
RPL11	5748.0	1403.0
RPL12	6107.0	-5604.0
RPL13	5686.0	-3760.0
RPL14	5110.0	-1875.0
RPL18	2523.0	-625.0
RPL18A	4545.0	-3218.0
RPL19	4654.0	6782.0
RPL21	-1686.0	8463.0
RPL22	2365.0	459.0
RPL22L1	-5123.0	-6294.0
RPL23	-205.0	4253.0
RPL24	-409.0	6813.0
RPL26	3650.0	8722.0
RPL28	6714.0	4753.0
RPL29	2613.0	4628.0
RPL3	5378.0	1155.0
RPL30	4372.0	3664.0
RPL31	6732.0	-1507.0
RPL32	2989.0	8728.0
RPL34	661.0	7140.0
RPL35	5949.0	8834.0
RPL35A	-1509.0	6565.0
RPL36	7543.0	-2424.0
RPL36A	-5983.0	4837.0
RPL36AL	1793.0	-2074.0
RPL37	2109.0	-667.0
RPL38	5601.0	5675.0
RPL3L	-5986.0	4937.0
RPL4	2582.0	8471.0
RPL6	572.0	7594.0
RPL7	-5186.0	8598.0
RPL8	3526.0	820.0
RPLP2	3550.0	3555.0
RPS13	7174.0	315.0
RPS14	4070.0	4443.0
RPS15	7253.0	6174.0
RPS16	6244.0	1119.0
RPS17	5667.0	7685.0
RPS18	4253.0	-526.0
RPS19	6565.0	-1215.0
RPS2	7322.0	4216.0
RPS21	7111.0	-6494.0
RPS25	4261.0	8455.0
RPS27A	-133.0	-1807.0
RPS28	7208.0	-396.0
RPS3	2340.0	4381.0
RPS3A	-3115.0	8824.0
RPS4X	2522.0	7391.0
RPS5	3848.0	7515.0
RPS6	-1700.0	8603.0
RPS8	3874.0	7646.0
RPS9	-1719.0	-2555.0
UBA52	7488.0	-4269.0

---

---

Extracellular matrix organization

Extracellular matrix organization

metric	value
setSize	252
pMANOVA	2.09e-10
p.adjustMANOVA	1.22e-08
s.dist	0.225
s.diabetes	0.0698
s.mitoG	0.214
p.diabetes	0.057
p.mitoG	4.94e-09

Top 20 genes

Gene	diabetes	mitoG
THBS1	8000	8780
COL12A1	8006	7991
KLK2	7226	8842
FN1	7489	8379
LOX	7282	7922
LOXL1	6829	8361
ICAM1	7342	7752
LAMC2	8173	6755
FBN1	6578	8391
SPARC	6297	8700
SH3PXD2A	7039	7748
BGN	6078	8647
COL6A2	6994	7492
TNC	7133	6992
LAMC1	7625	6528
LAMB2	7370	6700
COL4A2	5885	8130
BMP4	6672	7143
SPP1	8204	5504
EFEMP1	6611	6380

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
ACTN1	-2202.0	6473.0
ADAM10	-6444.0	8149.0
ADAM12	-6307.0	6119.0
ADAM15	7363.0	3763.0
ADAM17	-5121.0	3275.0
ADAM8	-5171.0	-1538.0
ADAM9	-5133.0	6361.0
ADAMTS1	-5452.0	8739.0
ADAMTS14	3645.0	-1429.0
ADAMTS16	6061.0	-5109.0
ADAMTS18	5565.0	-5223.0
ADAMTS2	-2074.0	8088.0
ADAMTS3	5455.0	1208.0
ADAMTS4	-4558.0	7178.0
ADAMTS5	4732.0	6838.0
ADAMTS8	3341.0	380.0
ADAMTS9	-4215.0	5871.0
AGRN	-2966.0	-6131.0
ASPN	2135.0	5403.0
BCAN	1188.0	-1033.0
BGN	6078.0	8647.0
BMP1	7824.0	-1166.0
BMP2	4300.0	7938.0
BMP4	6672.0	7143.0
BMP7	8109.0	-1080.0
BSG	-3166.0	5032.0
CAPN1	7308.0	-2267.0
CAPN10	2554.0	-6326.0
CAPN11	1426.0	-4379.0
CAPN12	4754.0	-5765.0
CAPN15	-874.0	-5739.0
CAPN2	5357.0	7435.0
CAPN3	3009.0	-6323.0
CAPN5	6382.0	3158.0
CAPN6	-4157.0	3121.0
CAPN7	-5214.0	8753.0
CAPNS1	1113.0	6245.0
CASK	5039.0	7114.0
CASP3	4881.0	3606.0
CAST	3920.0	8492.0
CD151	6017.0	4815.0
CD44	-4381.0	6982.0
CD47	-1991.0	7809.0
CDH1	-1038.0	5837.0
CEACAM1	3793.5	5357.5
CEACAM6	3793.5	5357.5
CEACAM8	3793.5	5357.5
COL11A2	-466.0	-5049.0
COL12A1	8006.0	7991.0
COL13A1	-2665.0	5999.0
COL14A1	4015.0	8124.0
COL15A1	-3945.0	2628.0
COL16A1	-2834.0	-1402.0
COL17A1	3604.0	-1512.0
COL18A1	199.0	218.0
COL19A1	-7333.0	1497.0
COL1A1	112.0	2092.0
COL1A2	416.0	5053.0
COL20A1	-395.0	-2498.0
COL23A1	6967.0	-509.0
COL25A1	-3823.0	-2146.0
COL26A1	3844.0	-6304.0
COL27A1	4578.0	-6600.0
COL28A1	635.0	2107.0
COL3A1	-2073.0	3836.0
COL4A1	-1913.0	7738.0
COL4A2	5885.0	8130.0
COL4A3	-7009.0	2651.0
COL4A4	-7080.0	-2678.0
COL4A5	-1115.0	-5623.0
COL4A6	-3205.0	1099.0
COL5A1	4033.0	733.0
COL5A2	-7225.0	4316.0
COL5A3	990.0	-5143.0
COL6A1	6555.0	6347.0
COL6A2	6994.0	7492.0
COL6A3	-3162.0	3589.0
COL6A5	-4190.0	6242.0
COL6A6	-7319.0	-1216.0
COL8A1	-3085.0	8177.0
COL8A2	1170.0	2569.0
COLGALT1	6399.0	362.0
COLGALT2	6749.0	1685.0
COMP	5760.0	-685.0
CRTAP	-4675.0	-2861.0
CTSB	7086.0	-1439.0
CTSD	5035.5	6716.5
CTSK	-3257.0	7753.0
CTSS	-5861.0	7572.0
DAG1	6646.0	3480.0
DCN	3643.0	8458.0
DDR1	6694.0	-6345.0
DDR2	-2604.0	8784.0
DMD	-1484.0	7317.0
DMP1	693.0	1827.0
DST	1303.0	1938.0
EFEMP1	6611.0	6380.0
EFEMP2	2292.0	7425.0
ELN	3735.0	-4141.0
F11R	2367.0	6083.0
FBLN1	1746.0	16.0
FBLN2	4810.0	7504.0
FBLN5	4332.0	8272.0
FBN1	6578.0	8391.0
FBN2	-2413.0	6151.0
FGA	4508.0	5893.0
FGB	3640.0	3338.0
FGF2	792.0	3696.0
FGG	5980.0	5427.0
FMOD	6304.0	4032.0
FN1	7489.0	8379.0
FURIN	3696.0	-3590.0
HAPLN1	-6240.0	1410.0
HSPG2	5843.0	5956.0
HTRA1	-6975.0	1980.0
ICAM1	7342.0	7752.0
ICAM2	-3483.0	7311.0
ICAM4	997.0	2998.0
ICAM5	526.0	-1886.0
ITGA1	491.0	8564.0
ITGA10	-5938.0	-5542.0
ITGA11	7742.0	4363.0
ITGA2	3883.0	2037.0
ITGA2B	4961.0	-4170.0
ITGA3	6960.0	5200.0
ITGA4	-6762.0	7.0
ITGA5	5929.0	6964.0
ITGA6	-6617.0	2201.0
ITGA7	6766.0	-5154.0
ITGA8	-802.0	4862.0
ITGA9	-6269.0	6974.0
ITGAE	935.0	-1407.0
ITGAL	-4315.0	-1137.0
ITGAM	3292.0	5515.0
ITGAV	8155.0	2693.0
ITGAX	-5859.0	2296.0
ITGB1	-6241.0	8758.0
ITGB2	-5238.0	412.0
ITGB3	1530.5	4298.5
ITGB4	7630.0	-2921.0
ITGB5	7359.0	1316.0
ITGB6	-7094.0	613.0
ITGB7	-4595.0	346.0
ITGB8	-1078.0	2920.0
JAM2	-4044.0	6849.0
JAM3	-6751.0	625.0
KDR	-4380.0	8170.0
KLK2	7226.0	8842.0
KLKB1	1003.0	5833.0
LAMA1	5185.0	-6681.0
LAMA2	-764.0	8779.0
LAMA3	-6292.0	-6746.0
LAMA4	-6624.0	4464.0
LAMA5	8212.0	-6404.0
LAMB1	1484.0	-2565.0
LAMB2	7370.0	6700.0
LAMB3	3108.0	-3030.0
LAMC1	7625.0	6528.0
LAMC2	8173.0	6755.0
LAMC3	-2856.0	4928.0
LOX	7282.0	7922.0
LOXL1	6829.0	8361.0
LOXL2	5024.0	8008.0
LOXL3	4869.0	6408.0
LOXL4	-1571.0	8483.0
LRP4	6743.0	-4824.0
LTBP1	-5412.0	7176.0
LTBP2	415.0	4760.0
LTBP3	8038.0	-540.0
LTBP4	-6699.0	5054.0
LUM	4367.0	7749.0
MATN4	7088.0	-6448.0
MFAP1	-1345.0	8624.0
MFAP2	6000.0	930.0
MFAP3	2866.0	4624.0
MFAP4	-1577.0	2378.0
MFAP5	479.0	5300.0
MMP11	-2364.0	1250.0
MMP12	-1805.0	-3875.0
MMP13	-6366.0	390.0
MMP14	2752.0	7195.0
MMP15	-6854.0	-344.0
MMP16	-4764.0	2029.0
MMP17	5193.0	-291.0
MMP19	6962.0	5702.0
MMP2	1375.0	7816.0
MMP24	2781.0	-6420.0
MMP25	525.0	-6432.0
MMP3	-598.0	1929.0
MMP9	-5717.0	1502.0
MUSK	1662.0	1545.0
NCAM1	-2962.0	3965.0
NCAN	1112.0	-3927.0
NCSTN	6534.0	860.0
NID1	2710.0	8751.0
NID2	-2779.0	3823.0
NRXN1	2691.0	-5064.0
NTN4	-2414.0	3491.0
OPTC	2184.0	-4930.0
P3H1	934.0	-3213.0
P3H2	7756.0	-6262.0
P3H3	1335.0	6621.0
P4HA1	-7269.0	6020.0
P4HA2	-6169.0	835.0
P4HA3	3311.0	-183.0
P4HB	-6743.0	5398.0
PCOLCE	6351.0	3187.0
PCOLCE2	5005.0	1293.0
PDGFA	4317.0	4142.0
PDGFB	-990.0	-1987.0
PECAM1	3970.0	8677.0
PHYKPL	6056.0	-4936.0
PLEC	8057.0	180.0
PLG	1632.0	-1603.0
PLOD1	-6201.0	5494.0
PLOD2	-7324.0	3272.0
PLOD3	-109.0	-1062.0
PPIB	2973.0	133.0
PRKCA	-6271.0	3380.0
PRSS1	-2444.0	-3110.0
PRSS2	-2444.0	-3110.0
PSEN1	-7020.0	6996.0
PTPRS	6647.0	-93.0
PXDN	-2822.0	7783.0
SCUBE1	1911.0	2119.0
SCUBE3	-5411.0	-4393.0
SDC1	6076.0	6227.0
SDC2	-6850.0	7623.0
SDC3	5919.0	4486.0
SDC4	6585.0	816.0
SERPINE1	2322.0	8202.0
SERPINH1	-7218.0	4296.0
SH3PXD2A	7039.0	7748.0
SPARC	6297.0	8700.0
SPOCK3	-4964.0	1946.0
SPP1	8204.0	5504.0
TGFB1	-1851.0	6152.0
TGFB2	4490.0	6652.0
TGFB3	-1546.0	8322.0
THBS1	8000.0	8780.0
TIMP1	-2454.0	3444.0
TIMP2	4104.0	8646.0
TLL1	-559.0	4808.0
TMPRSS6	3770.0	-4345.0
TNC	7133.0	6992.0
TNN	5966.0	-4030.0
TNR	-765.0	-824.0
TNXB	5424.0	759.0
TRAPPC4	-1321.0	-410.0
TTR	-6090.0	3451.0
VCAM1	-4983.0	4280.0
VCAN	-3773.0	1454.0

---

---

Metabolism

Metabolism

metric	value
setSize	1871
pMANOVA	2.52e-10
p.adjustMANOVA	1.41e-08
s.dist	0.0841
s.diabetes	0.0664
s.mitoG	0.0516
p.diabetes	2.99e-06
p.mitoG	0.000285

Top 20 genes

Gene	diabetes	mitoG
GSTM1	8251	8764
ALDH1A1	8263	8314
GSTM3	7984	8484
NAMPT	8078	8082
CYGB	7666	8450
ENO1	8244	7737
CYP1B1	7373	8462
LRP1	7344	8465
FABP4	7019	8615
IQGAP1	7427	8123
FABP3	7954	7448
PKM	7561	7758
PLCB4	7393	7817
PGM2	7401	7591
CBR3	8089	6841
PFKFB3	7737	7129
ACER2	7558	7227
PLPP1	6991	7651
COX7B	6102	8760
CBR1	8220	6483

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
AAAS	5561.0	-2261.0
AACS	-5360.0	-2533.0
AADAC	-4562.0	6259.0
AADAT	-7199.0	3349.0
AANAT	-796.0	2183.0
AASDHPPT	1006.0	-284.0
AASS	-5588.0	6592.0
ABCA1	4025.0	-5420.0
ABCB1	7896.0	-2893.0
ABCB4	2164.0	-5686.0
ABCB7	-5950.0	8196.0
ABCC1	8032.0	692.0
ABCC2	8240.0	5236.0
ABCC3	8151.0	1041.0
ABCC5	4476.0	-5612.0
ABCD1	3997.0	-5967.0
ABCD4	8139.0	-5758.0
ABCG2	-5085.0	3477.0
ABHD10	149.0	3960.0
ABHD14B	325.0	-5891.0
ABHD3	-7129.0	889.0
ABHD4	7773.0	-1515.0
ABHD5	2617.0	5120.0
ACAA1	7141.0	-6777.0
ACAA2	7057.0	2088.0
ACACA	-6585.0	2967.0
ACACB	8218.0	-2457.0
ACAD10	-7041.0	-6762.0
ACAD11	3659.0	5823.0
ACAD8	-344.0	-5840.0
ACAD9	-4848.0	-2818.0
ACADL	-4605.0	7358.0
ACADM	-6050.0	5877.0
ACADS	-6745.0	-2069.0
ACADSB	-680.0	7886.0
ACADVL	-1391.0	91.0
ACAT1	-7321.0	6527.0
ACAT2	7049.0	5165.0
ACBD4	-3120.0	-2767.0
ACBD5	-3255.0	8503.0
ACBD6	5740.0	-4665.0
ACER2	7558.0	7227.0
ACER3	273.0	2121.0
ACHE	7193.0	2151.0
ACLY	394.0	2995.0
ACMSD	-5646.0	3995.0
ACO2	7295.0	7282.0
ACOT1	8260.5	-4673.5
ACOT11	-2431.0	5329.0
ACOT12	-6425.0	5937.0
ACOT13	-3078.0	8794.0
ACOT2	8260.5	-4673.5
ACOT4	1724.0	-1405.0
ACOT6	4179.0	-3605.0
ACOT7	5176.0	6820.0
ACOT8	405.0	-2977.0
ACOT9	-5708.0	8538.0
ACOX1	-7025.0	5178.0
ACOX2	6388.0	6251.0
ACOX3	2698.0	1941.0
ACP5	-2877.0	60.0
ACP6	8136.0	-6527.0
ACSBG1	6947.0	2475.0
ACSF2	8252.0	3946.0
ACSF3	-2888.0	-2519.0
ACSL1	318.0	3006.0
ACSL3	4910.0	5105.0
ACSL4	3990.0	7507.0
ACSL5	6398.0	6307.0
ACSL6	-1434.5	2340.5
ACSM1	1498.0	-3023.0
ACSM2A	-7294.5	1878.5
ACSM2B	-7294.5	1878.5
ACSM3	-7280.0	3961.0
ACSM5	7609.0	-5870.0
ACSS1	6409.0	-3116.0
ACSS2	-6243.0	-4552.0
ACSS3	2234.0	6914.0
ACY1	-1207.5	-4016.5
ACY3	-6986.0	-1176.0
ADA	-2063.0	7784.0
ADAL	-7032.0	3196.0
ADCY1	-4196.0	1876.0
ADCY2	5891.0	1358.0
ADCY3	-351.0	4656.0
ADCY4	-237.0	7618.0
ADCY5	2277.0	2395.0
ADCY6	7278.0	-6203.0
ADCY7	-5272.0	-2210.0
ADCY8	3778.0	-3880.0
ADCY9	2137.0	-5459.0
ADH1A	-7312.0	7343.0
ADH1B	-7312.0	7343.0
ADH1C	-7312.0	7343.0
ADH5	842.0	5108.0
ADH6	1174.0	-855.0
ADH7	-6558.0	1235.0
ADHFE1	-6733.0	240.0
ADI1	-1649.0	2833.0
ADIPOQ	3018.0	-3550.0
ADIPOR1	1903.0	4488.0
ADIPOR2	-4637.0	5912.0
ADK	-3517.0	5789.0
ADO	-1293.0	4866.0
ADPGK	-1319.0	-354.0
ADPRM	462.0	2598.0
ADRA2A	6239.0	-2148.0
ADRA2C	3959.0	-2881.0
ADSL	2344.0	-1198.0
AFMID	-6775.0	-1357.0
AGK	2444.0	4916.0
AGL	6768.0	2825.0
AGMAT	802.0	-3944.0
AGMO	-3225.0	-629.0
AGPAT1	-23.0	-2474.0
AGPAT2	-4051.0	-2429.0
AGPAT3	-4447.0	-444.0
AGPAT4	-952.0	3991.0
AGPAT5	6259.0	395.0
AGPS	-7336.0	594.0
AGRN	-2966.0	-6131.0
AGT	8188.0	618.0
AGXT2	-998.0	1005.0
AHCY	-3362.0	-6342.0
AHCYL1	-5585.0	5114.0
AHR	2185.5	5110.5
AIMP1	3483.0	-4465.0
AIMP2	3676.0	2367.0
AIP	-549.0	3479.0
AK1	6519.0	7024.0
AK2	3153.0	197.0
AK4	6498.0	456.0
AK5	1870.0	7881.0
AK7	7352.0	-2905.0
AK9	3380.0	-6198.0
AKAP5	6430.0	224.0
AKR1A1	816.0	1669.0
AKR1B1	-6331.0	1586.0
AKR1B10	-7156.0	8303.0
AKR1D1	6533.0	3912.0
AKR7L	-1281.0	-6094.0
AKT1	4859.0	7244.0
ALAD	2122.0	-5915.0
ALAS1	-5159.0	874.0
ALAS2	1111.0	6668.0
ALB	6253.0	-380.0
ALDH18A1	140.0	-1710.0
ALDH1A1	8263.0	8314.0
ALDH1B1	8174.0	2232.0
ALDH1L1	6855.0	945.0
ALDH1L2	-6035.0	-2794.0
ALDH2	6746.5	-4906.5
ALDH3A1	-3874.0	3587.0
ALDH3A2	-7300.0	-220.0
ALDH3B1	7287.0	4258.0
ALDH3B2	-6971.0	-6115.0
ALDH4A1	3213.0	-5888.0
ALDH6A1	-2335.0	6484.0
ALDH7A1	3749.0	3717.0
ALDOA	6979.5	3652.5
ALDOB	6728.0	7388.0
ALDOC	8058.0	-926.0
ALOX12	3935.0	-912.0
ALOX15B	4171.0	-4470.0
ALOX5	5079.0	-1468.0
ALOX5AP	-1117.0	7096.0
ALOXE3	2780.0	-5548.0
AMACR	-7290.0	-2238.0
AMD1	-6466.0	6443.0
AMDHD1	4717.0	1229.0
AMN	-3075.0	-6644.0
AMPD2	-5842.0	-3639.0
AMPD3	7453.0	2602.0
AMT	7787.0	1845.0
ANGPTL4	1374.0	2720.0
ANKRD1	-2201.0	5290.0
AOC1	5592.0	-5405.0
AOC2	3094.0	-4208.0
AOC3	-497.0	5099.0
AOX1	-1392.0	452.0
APIP	1979.0	6328.0
APOA1	3682.0	-305.0
APOA2	5921.0	5590.0
APOA4	-3638.0	-1066.0
APOB	7604.0	5782.0
APOC2	5909.0	-2525.0
APOC3	6933.0	-4086.0
APOE	5835.0	342.0
APOM	-5448.0	-3495.0
APRT	7257.0	-2499.0
ARF1	-5273.0	7470.0
ARF3	4831.5	-5103.5
ARG1	203.0	-1236.0
ARG2	8093.0	6088.0
ARNT	1247.0	2255.0
ARNT2	8205.0	310.0
ARNTL	-7061.0	4190.0
ARSA	4080.0	-2367.0
ARSB	-5231.0	2994.0
ARSG	-6486.0	-3133.0
ARSI	-5854.0	1182.0
ARSJ	-4150.0	1548.0
ARSK	-3950.0	5751.0
ARV1	4966.0	-4696.0
AS3MT	-3132.0	-191.0
ASAH1	-720.0	8441.0
ASAH2	-3814.5	3785.5
ASL	7699.5	-4876.5
ASNS	419.0	3160.0
ASPA	2790.0	7071.0
ASPG	-3575.0	-6380.0
ASRGL1	8192.0	1093.0
ASS1	-6686.0	-610.0
ATIC	-1769.0	3784.0
ATP5F1A	6316.0	1471.0
ATP5F1B	1691.0	1750.0
ATP5F1C	164.0	8242.0
ATP5F1D	5225.0	673.0
ATP5F1E	6241.0	-5774.0
ATP5MC3	6278.0	-5724.0
ATP5ME	3268.0	3202.0
ATP5MF	6860.0	-1957.0
ATP5MG	5923.5	564.5
ATP5PB	1124.0	5544.0
ATP5PD	5135.0	6133.0
ATP5PF	710.0	7012.0
ATP5PO	6640.5	7456.5
AUH	-5162.0	2525.0
AWAT2	-3488.0	881.0
AZIN1	6036.0	4792.0
AZIN2	8026.0	-5538.0
B3GALNT1	6544.0	-2670.0
B3GALT1	1591.0	8344.0
B3GALT2	-3274.0	-198.0
B3GALT4	-445.0	-1518.0
B3GALT5	-4219.0	8.0
B3GALT6	-4238.0	3876.0
B3GAT1	5839.0	-5131.0
B3GAT2	-7055.0	-4630.0
B3GAT3	-4118.0	-2576.0
B3GNT2	830.0	-6274.0
B3GNT3	-3777.0	7172.0
B3GNT4	1421.0	-968.0
B3GNT7	6328.0	-3498.0
B4GALNT1	8077.0	1664.0
B4GALT1	-356.0	-3621.0
B4GALT2	6215.0	627.0
B4GALT3	-1790.0	-3235.0
B4GALT4	6095.0	4039.0
B4GALT5	-7316.0	-2072.0
B4GALT6	-2315.0	8205.0
B4GALT7	1147.0	-2488.0
B4GAT1	7224.0	-6185.0
BAAT	6231.0	-2945.0
BBOX1	6577.0	5810.0
BCAN	1188.0	-1033.0
BCAT1	-1255.0	2962.0
BCAT2	7659.0	-5016.0
BCHE	111.0	-2916.0
BCKDHA	-62.5	-2425.5
BCKDHB	36.0	-194.0
BCKDK	478.0	-144.0
BCO1	7310.0	4596.0
BCO2	-6189.0	2216.0
BDH1	-7240.0	-1369.0
BDH2	-130.0	5389.0
BGN	6078.0	8647.0
BHMT	8249.0	5797.0
BHMT2	7244.0	-3954.0
BLVRA	1514.0	1000.0
BLVRB	-1146.0	1801.0
BMX	5552.0	4493.0
BPGM	-2704.0	7858.0
BPHL	-6521.0	-4387.0
BPNT1	-3896.0	2288.0
BPNT2	-4589.0	6495.0
BRIP1	6470.0	3893.0
BSG	-3166.0	5032.0
BST1	5884.0	6856.0
BTD	-3970.0	1048.0
CA12	4650.0	455.0
CA13	1859.0	3714.0
CA14	6441.0	-2711.0
CA2	8153.0	4609.0
CA3	-6741.0	-3767.0
CA4	-6448.0	2608.0
CA5A	5444.0	-876.0
CA5B	-4709.0	3804.0
CA7	423.0	-871.0
CA9	-2361.0	-2782.0
CACNA1A	1894.0	-3861.0
CACNA1C	-234.0	-2843.0
CACNA1D	1453.0	-2159.0
CACNA1E	-3623.0	599.0
CACNA2D2	2606.0	-5092.0
CACNB2	5838.0	-5134.0
CACNB3	7396.0	5397.0
CAD	838.0	-2174.0
CALM1	-4401.0	8702.0
CARM1	4760.0	-3487.0
CARNMT1	-4574.0	8711.0
CARNS1	4024.0	-4535.0
CAV1	875.0	7970.0
CBR1	8220.0	6483.0
CBR3	8089.0	6841.0
CBR4	5983.0	4273.0
CBS	-7221.5	-107.5
CBSL	-7221.5	-107.5
CCNC	-3288.0	7605.0
CD320	3164.0	-4419.0
CD36	-7328.0	6006.0
CD38	1648.0	8507.0
CD44	-4381.0	6982.0
CDA	4457.0	-5554.0
CDIPT	-719.0	3299.0
CDK19	5061.0	2530.0
CDK8	5984.0	-5196.0
CDO1	7167.0	3522.0
CDS1	7794.0	278.0
CDS2	6158.0	1277.0
CEMIP	6626.0	1672.0
CEPT1	152.0	2535.0
CERK	2319.0	7635.0
CERS1	-393.5	-2230.5
CERS2	-4557.0	5723.0
CERS3	2575.0	1128.0
CERS4	6759.0	-3788.0
CERS5	-7047.0	1127.0
CERS6	-1584.0	1516.0
CERT1	-6753.0	5925.0
CES1	-7348.0	-6736.0
CES2	-7346.0	-5557.0
CES3	-1311.0	-110.0
CH25H	-248.0	7543.0
CHAC1	-5498.0	4031.0
CHAC2	-5848.0	6786.0
CHD9	-6925.0	8050.0
CHDH	-5072.0	-2118.0
CHKA	-322.0	-6160.0
CHKB	5380.0	4163.0
CHP1	5044.0	6993.0
CHPF	638.0	-574.0
CHPF2	6495.0	-6473.0
CHPT1	-6923.0	8136.0
CHRM3	-4917.0	-1118.0
CHST1	-699.0	6615.0
CHST11	-7098.0	3453.0
CHST12	1933.0	4650.0
CHST13	-3449.0	-3752.0
CHST14	5900.0	-4857.0
CHST15	3492.0	3996.0
CHST2	2012.0	6764.0
CHST3	-96.0	2845.0
CHST7	-7015.0	-984.0
CHST9	-3233.0	-153.0
CHSY1	-1431.0	5798.0
CHSY3	4571.0	-2850.0
CIAO1	2402.0	4375.0
CIAO2B	5422.0	-6319.0
CIAO3	1942.0	-1857.0
CIAPIN1	6552.0	-65.0
CIDEA	857.0	1349.0
CIDEC	6723.0	-3643.0
CKB	6823.0	-643.0
CKM	-1393.0	-315.0
CKMT1A	7936.5	2974.5
CLOCK	-7043.0	8412.0
CMBL	-2275.0	4334.0
CMPK1	1010.0	8706.0
CNDP2	-7084.0	27.0
COASY	-5559.0	-3804.0
COMT	-7046.0	5137.0
COQ10A	7831.0	-5063.0
COQ10B	219.0	7422.0
COQ2	294.0	-1909.0
COQ3	-723.0	5126.0
COQ5	-3376.0	1720.0
COQ6	1950.0	-3453.0
COQ7	6219.0	-4873.0
COQ9	2870.0	1480.0
COX10	2047.0	2856.0
COX11	742.0	-1169.0
COX14	2703.0	-3376.0
COX16	-3433.0	7416.0
COX18	5019.0	1575.0
COX19	-2099.0	3124.0
COX20	-4714.0	6792.0
COX4I1	6324.0	-2473.0
COX5B	7740.0	-2295.0
COX6A1	5658.0	-2138.0
COX6B1	5091.0	7299.0
COX6C	7537.0	1755.0
COX7A2L	4007.0	4780.0
COX7B	6102.0	8760.0
COX7C	4066.0	-5285.0
COX8A	5622.0	-4787.0
CPNE1	4530.0	-1637.0
CPNE3	1709.0	7633.0
CPNE7	6372.0	-414.0
CPOX	-7263.0	-1598.0
CPT1A	5912.0	-394.0
CPT1B	7757.0	2397.0
CPT2	1534.0	7215.0
CPTP	-4095.0	-2085.0
CRAT	6421.0	3643.0
CREBBP	-6181.0	3954.0
CRLS1	-385.0	5733.0
CROT	-6382.0	6260.0
CRYL1	7236.0	1237.0
CRYM	4812.0	-4610.0
CS	5645.0	5457.0
CSAD	-6071.0	-2994.0
CSGALNACT1	-6929.0	4339.0
CSGALNACT2	1218.0	8156.0
CSNK1G2	3468.0	1562.0
CSNK2A1	-1453.5	2755.5
CSNK2A2	-2373.0	3684.0
CSNK2B	-3628.0	6622.0
CSPG4	8154.0	-6277.0
CSPG5	-1773.0	-788.0
CTH	6814.0	3635.0
CTPS1	472.0	7421.0
CTPS2	-5502.0	3855.0
CTSA	6070.0	1611.0
CUBN	5596.0	263.0
CYB5A	-6903.0	6876.0
CYB5B	1592.0	2885.0
CYB5R3	1442.0	4432.0
CYC1	7497.0	-4809.0
CYGB	7666.0	8450.0
CYP11A1	-1866.0	5478.0
CYP17A1	5201.0	-486.0
CYP1A1	2077.0	-910.0
CYP1B1	7373.0	8462.0
CYP24A1	5963.0	4072.0
CYP26A1	1295.0	-4310.0
CYP26B1	-3693.0	4378.0
CYP26C1	602.0	-5399.0
CYP27A1	7503.0	3659.0
CYP27B1	4131.0	-2865.0
CYP2D6	7172.5	-2324.5
CYP2E1	-7252.0	4835.0
CYP2F1	-2718.0	-2883.0
CYP2J2	-6641.0	-623.0
CYP2R1	-4480.0	2939.0
CYP2S1	8208.0	917.0
CYP2U1	4939.0	30.0
CYP39A1	6511.0	6762.0
CYP3A4	399.0	1822.0
CYP3A43	399.0	1822.0
CYP3A5	399.0	1822.0
CYP3A7	399.0	1822.0
CYP46A1	1803.0	124.0
CYP4A11	7297.5	2796.5
CYP4A22	7297.5	2796.5
CYP4B1	-7352.0	-5261.0
CYP4F11	7297.5	2796.5
CYP4F12	7297.5	2796.5
CYP4F2	6042.0	596.0
CYP4F3	9.0	6130.0
CYP4F8	8150.0	-6752.0
CYP4V2	7248.0	5952.0
CYP51A1	39.0	-254.0
CYP7B1	-5009.0	2252.0
D2HGDH	-4629.0	-6471.0
DAO	-4052.0	-4438.0
DARS1	-2473.0	7683.0
DBI	-3860.0	5119.0
DBT	-3829.0	5868.0
DCK	3738.0	-4745.0
DCN	3643.0	8458.0
DCT	269.0	-2689.0
DCTD	-3347.0	491.0
DCTPP1	6720.0	-2879.0
DCXR	5278.0	-4512.0
DDAH1	-5433.0	2105.0
DDAH2	7098.0	2607.0
DDC	-2469.0	2727.0
DDHD1	-5480.0	1180.0
DDHD2	7101.0	5488.0
DDO	-6719.0	-6459.0
DECR1	4945.0	7687.0
DECR2	7261.0	1056.0
DEGS1	-4450.0	2479.0
DEGS2	-7330.0	-1773.0
DERA	5742.0	3035.0
DGAT1	5332.0	-6609.0
DGAT2	7540.0	-5155.0
DGUOK	1237.0	-5169.0
DHCR24	-3812.0	-2962.0
DHCR7	3894.0	-5672.0
DHFR	-6938.5	6873.5
DHFR2	-6938.5	6873.5
DHODH	6617.0	-2871.0
DHRS7B	-2769.0	-1952.0
DHTKD1	4800.0	-3721.0
DIO1	-4596.0	-5730.0
DIO3	-3649.0	2794.0
DLAT	3962.0	2209.0
DLD	-2523.0	7607.0
DLST	6249.0	251.0
DMAC2L	1623.0	-997.0
DMGDH	6425.0	1956.0
DNM2	-1598.0	5364.0
DNPH1	-3818.0	-3162.0
DPEP1	1301.0	5412.0
DPEP2	3373.0	1639.0
DPYD	4469.0	5022.0
DPYS	-4056.0	-2655.0
DSE	-3808.5	7930.5
DSEL	1263.0	4387.0
DTYMK	-200.0	217.0
DUOX1	5677.0	-1910.0
DUT	1159.0	688.0
ECHS1	1581.0	1330.0
ECI1	7152.0	3824.0
ECI2	4491.0	7297.0
ECSIT	-3596.0	1408.0
EEF1E1	-2005.5	5771.5
EEFSEC	-2350.0	5663.0
EHHADH	-5253.0	4465.0
ELOVL1	3466.0	529.0
ELOVL2	7550.0	5176.0
ELOVL5	-49.0	7269.0
ELOVL6	8138.0	3754.0
ELOVL7	-6364.0	4757.0
ENO1	8244.0	7737.0
ENO2	3279.0	-2394.0
ENO3	2281.0	-3777.0
ENOPH1	553.0	-4737.0
ENPP1	-4115.0	6101.0
ENPP2	1844.0	7459.0
ENPP3	-2192.0	112.0
ENPP6	6053.0	6381.0
ENTPD1	6740.0	7163.0
ENTPD2	3687.0	-5847.0
ENTPD3	5017.0	-1193.0
ENTPD4	-7304.0	2812.0
ENTPD5	6385.0	3766.0
ENTPD6	10.0	-2323.0
ENTPD7	-6301.0	-4494.0
ENTPD8	4053.0	-6480.0
EP300	-2449.0	1336.0
EPHX1	8264.0	5005.0
EPHX2	-6957.0	6315.0
EPM2A	6139.0	-2279.0
EPRS1	-5855.0	8062.0
ERCC2	6295.0	-6411.0
ESD	771.0	8516.0
ESRRA	2985.0	-5733.0
ESYT1	5525.0	5513.0
ESYT2	-5265.0	8330.0
ESYT3	2393.0	5452.0
ETFA	-4953.0	3129.0
ETFB	5896.0	-2345.0
ETFDH	-5320.0	8131.0
ETHE1	-5582.0	-267.0
ETNK1	7979.0	553.0
ETNK2	163.0	-275.0
ETNPPL	3515.0	911.0
EXT1	-1529.0	4370.0
EXT2	3219.0	2652.0
FA2H	7467.0	-4749.0
FAAH	-5982.0	-3722.0
FABP1	289.0	-1810.0
FABP12	-907.0	-970.0
FABP3	7954.0	7448.0
FABP4	7019.0	8615.0
FABP5	3630.0	2188.0
FABP7	-2994.0	-570.0
FADS1	2801.0	-1482.0
FADS2	-6324.0	-4233.0
FAH	-5796.0	3415.0
FAHD1	-5635.0	4647.0
FAM120B	-5510.0	-1760.0
FAR1	-7102.0	4677.0
FAR2	-2712.0	888.0
FASN	-6300.0	-2272.0
FAU	6809.0	7710.0
FBP1	7186.0	2802.0
FBP2	8143.0	1918.0
FDFT1	6554.0	2513.0
FDPS	4292.0	245.0
FDX1	-3799.0	389.0
FDX2	-5934.5	5631.5
FECH	-4321.0	4721.0
FFAR1	-5105.0	-4068.0
FH	1716.0	7771.0
FHL2	-1852.0	5431.0
FIG4	-2261.0	2661.0
FITM1	7108.0	-2940.0
FITM2	5248.0	2277.0
FLAD1	-5703.0	-2876.0
FLVCR1	-1246.0	7750.0
FMO1	-4045.0	920.0
FMO2	-338.0	3782.0
FMO3	3331.0	5124.0
FMOD	6304.0	4032.0
FOLH1	4408.0	7319.0
FOLR2	4808.5	-5490.5
FPGS	6063.0	-2374.0
FTCD	7694.0	-4246.0
FUT10	2991.0	3962.0
FUT11	-3847.0	5724.0
FUT4	2474.0	-2219.0
FUT9	-7068.0	589.0
FXN	-1871.0	-4045.0
G0S2	4904.0	8051.0
G6PC	-4387.0	3036.0
G6PC3	-77.0	-5754.0
G6PD	2502.0	7051.0
GAA	-3821.0	-2398.0
GADL1	-2735.0	-1392.0
GALC	-3406.0	-365.0
GALE	-148.0	-1536.0
GALK1	5722.0	-6298.0
GALT	7317.0	-476.0
GAMT	1939.0	-2827.0
GAPDHS	-249.0	-6258.0
GART	-5631.0	-3257.0
GATM	1838.0	-1859.0
GBA	-5712.0	-3677.0
GBA2	6997.0	-4605.0
GBE1	-1656.0	8320.0
GC	7207.0	3694.0
GCAT	6985.0	-6375.0
GCDH	1309.0	-1075.0
GCH1	4316.0	-364.0
GCHFR	-3398.0	-4697.0
GCLC	3508.0	7117.0
GCLM	-6988.0	3072.0
GCSH	-1164.0	3185.0
GDA	852.0	8466.0
GDE1	5901.0	6082.0
GDPD1	5913.0	3917.0
GDPD3	374.0	-1696.0
GDPD5	7592.0	424.0
GGCT	-7288.5	-91.5
GGPS1	-2197.0	7394.0
GGT1	-7165.0	-1432.0
GGT5	1563.0	6027.0
GGT6	-4120.0	-5773.0
GGT7	4301.0	-3676.0
GK	-4767.5	4354.5
GK3P	-4767.5	4354.5
GLA	1196.0	3449.0
GLB1	-5376.0	2645.0
GLB1L	-4737.0	-6402.0
GLCE	126.0	1372.0
GLDC	7372.0	2441.0
GLIPR1	-4306.0	6128.0
GLO1	-6305.0	1741.0
GLP1R	-3107.0	1309.0
GLRX	7656.0	5593.0
GLRX5	6724.0	4490.0
GLS	5704.0	3155.0
GLS2	-2921.0	4986.0
GLTP	6712.0	2740.0
GLUD1	8064.5	3730.5
GLUD2	8064.5	3730.5
GLUL	7900.0	3064.0
GLYAT	-2269.0	6292.0
GLYCTK	-6977.0	-4843.0
GM2A	7424.0	6766.0
GMPR	-6825.0	-1592.0
GMPR2	-4747.0	4135.0
GMPS	-5160.0	8238.0
GNA11	5503.0	2824.0
GNA14	-6262.0	5551.0
GNA15	-5378.0	2207.0
GNAI1	-6368.0	8547.0
GNAI2	6737.0	5825.0
GNAS	-2825.0	5946.0
GNB1	1685.0	7974.0
GNB2	5389.0	-1847.0
GNB4	-4648.0	2711.0
GNB5	4543.0	3032.0
GNG10	5845.0	2921.0
GNG11	-2960.0	5884.0
GNG12	-1212.0	6898.0
GNG2	4011.0	7569.0
GNG3	-1825.0	1443.0
GNG4	-653.0	-591.0
GNG5	-2879.0	-1254.0
GNG7	1904.0	-4062.0
GNG8	499.0	-762.0
GNGT1	1972.0	5695.0
GNGT2	-1053.0	5102.0
GNMT	-1249.0	1292.0
GNPAT	-6628.0	-27.0
GNPDA1	-6824.0	-4338.0
GNPDA2	3486.0	6823.0
GNS	8072.0	1691.0
GOT1	7006.0	7048.0
GOT2	7334.0	4691.0
GPAM	5406.0	-2586.0
GPAT2	946.0	-6428.0
GPAT3	7966.0	-4186.0
GPAT4	-5864.0	-1977.0
GPC1	7890.0	581.0
GPC2	-2976.0	-1110.0
GPC3	-3602.0	6611.0
GPC4	-6484.0	-3662.0
GPC5	-4977.0	-3337.0
GPC6	-257.0	7981.0
GPCPD1	653.0	2680.0
GPD1	7303.0	5439.0
GPD1L	7492.0	4085.0
GPD2	-5845.0	8339.0
GPHN	-689.0	-3117.0
GPI	4816.0	5422.0
GPIHBP1	4244.0	8224.0
GPS2	1228.0	2826.0
GPT	8225.0	-4250.0
GPT2	8165.0	-649.0
GPX1	-1077.0	736.0
GPX4	7228.0	5272.0
GRHL1	2470.0	-2328.0
GRHPR	-5455.0	-5257.0
GSR	-2480.0	4329.0
GSS	-4718.0	305.0
GSTA5	7251.0	2743.0
GSTK1	2643.0	6138.0
GSTM1	8251.0	8764.0
GSTM2	5554.0	5220.0
GSTM3	7984.0	8484.0
GSTM4	4234.0	654.0
GSTO1	8023.0	4922.0
GSTO2	5447.0	-1374.0
GSTP1	1683.0	2544.0
GSTT2	7774.5	-5210.5
GSTT2B	7774.5	-5210.5
GSTZ1	-3082.0	5598.0
GUK1	7026.0	4055.0
GUSB	-7203.0	1338.0
GYG1	27.0	6415.0
GYS1	8121.0	-4022.0
GYS2	-6113.0	3883.0
HAAO	-6024.0	3312.0
HACD1	-838.0	6491.0
HACD2	-7241.0	2435.0
HACD3	-5973.0	6805.0
HACD4	-4926.0	7518.0
HACL1	8256.0	3314.0
HADH	-3651.0	5063.0
HADHA	6883.0	5617.0
HADHB	6459.0	2869.0
HAGH	1822.0	7296.0
HAL	1725.0	-1865.0
HAO2	6573.0	631.0
HAS1	2970.0	-5455.0
HAS3	-1735.0	-3207.0
HDAC3	5142.0	-772.0
HDC	7382.0	703.0
HELZ2	1736.0	2464.0
HEXA	6254.5	2667.5
HEXB	-6611.0	-740.0
HGD	-2104.0	3212.0
HIBADH	-6508.0	6140.0
HIBCH	-4783.0	7660.0
HILPDA	1566.0	3374.0
HK1	7506.0	4598.0
HK2	-1356.0	5521.0
HK3	-4874.0	2139.0
HLCS	5973.0	-4716.0
HMBS	2651.0	6449.0
HMGCL	1207.0	-3452.0
HMGCLL1	1540.0	-542.0
HMGCR	-4034.0	4466.0
HMGCS1	-388.0	4778.0
HMGCS2	3330.0	3901.0
HMMR	2994.0	-361.0
HMOX1	-7076.0	8232.0
HMOX2	-1566.0	6596.0
HNMT	-3291.0	6285.0
HOGA1	7205.0	-518.0
HPD	4766.0	2957.0
HPGD	-6103.0	8382.0
HPGDS	-3316.0	-1383.0
HPRT1	-5564.0	8025.0
HPSE	50.0	-1095.0
HPSE2	3701.0	-4964.0
HS2ST1	-1148.5	4146.5
HS3ST1	-5059.0	5553.0
HS3ST3A1	1912.0	1147.0
HS3ST3B1	2983.0	5715.0
HS3ST4	-156.0	-2163.0
HS3ST6	4461.0	341.0
HS6ST1	-6211.0	-2451.0
HS6ST2	-3118.0	6008.0
HSCB	6052.0	899.0
HSD11B1	-6726.0	8736.0
HSD11B2	6296.0	-5756.0
HSD17B1	2011.0	-3431.0
HSD17B10	3539.0	5976.0
HSD17B11	-7357.0	3697.0
HSD17B12	-6789.0	7609.0
HSD17B13	3226.0	314.0
HSD17B14	3622.0	2211.0
HSD17B2	-7196.0	1405.0
HSD17B4	4847.0	3866.0
HSD17B7	6005.0	7932.0
HSD17B8	-1625.0	-1841.0
HSD3B7	5974.0	-3014.0
HSP90AA1	-7286.0	8742.0
HSP90AB1	-7306.0	5626.0
HSPG2	5843.0	5956.0
HYAL1	5242.0	3316.0
HYAL2	-2781.0	-4258.0
HYAL3	-1924.0	-1820.0
HYKK	-7190.0	345.0
IARS1	-5409.0	3400.0
IDH1	5264.0	7348.0
IDH2	155.0	1563.0
IDH3A	-958.0	7080.0
IDH3B	3081.0	573.0
IDH3G	-4880.0	6728.0
IDI1	-6203.0	2809.0
IDI2	1402.0	-1734.0
IDO1	2509.0	-1826.0
IDO2	-5852.0	-3853.0
IDS	-4361.5	6034.5
IDUA	4110.0	3194.0
IL4I1	5852.0	-6446.0
IMPA1	-6235.0	-4446.0
IMPA2	7206.0	-2131.0
IMPDH1	1190.0	4821.0
IMPDH2	4946.0	4658.0
INMT	-7247.5	-5918.5
INPP1	-2190.0	3769.0
INPP4A	-1389.0	-2681.0
INPP4B	1326.0	8582.0
INPP5A	5585.0	6455.0
INPP5B	-4419.0	6670.0
INPP5D	-1230.0	5535.0
INPP5E	6856.0	-5834.0
INPP5F	-1302.0	1035.0
INPP5J	-2788.0	-4756.0
INPP5K	8149.0	-2011.0
INPPL1	-1829.0	-4396.0
INSIG1	7013.0	2263.0
INSIG2	-56.0	1759.0
IP6K1	3638.0	-3338.0
IP6K2	6791.0	1576.0
IP6K3	-1736.0	2577.0
IPMK	-5288.0	1204.0
IPPK	-1989.0	8204.0
IQGAP1	7427.0	8123.0
ISCA1	3586.0	898.0
ISCA2	4512.0	-228.0
ISCU	6516.0	6763.0
ISYNA1	7838.0	-3584.0
ITPA	-2672.0	-3373.0
ITPK1	-6865.0	-2177.0
ITPKA	1122.0	-2506.0
ITPKB	4042.0	6200.0
ITPKC	4739.0	-3665.0
ITPR1	-2727.0	2512.0
ITPR2	4185.0	-2206.0
ITPR3	7844.0	5234.0
IVD	-7031.0	-4194.0
IYD	2990.0	6472.0
KARS1	3885.0	5716.0
KCNB1	5451.0	5500.0
KCNC2	4321.0	-1522.0
KCNG2	2399.0	-3987.0
KCNJ11	2961.0	-3265.0
KCNS3	-263.0	1598.0
KDSR	-6553.0	1366.0
KHK	-1811.0	2087.0
KMO	-5997.0	2708.0
KPNB1	-1668.0	5829.0
KYAT1	1116.5	5507.5
KYAT3	4242.0	3058.0
KYNU	8271.0	-1487.0
L2HGDH	1057.0	-1650.0
LARS1	7823.0	-1599.0
LBR	-744.0	-2779.0
LCLAT1	3963.0	6633.0
LDHA	-5897.0	843.0
LDHAL6B	2680.0	-6086.0
LDHB	5412.5	4669.5
LDLR	4229.0	3193.0
LGMN	7268.0	624.0
LHPP	4888.0	808.0
LIAS	1365.0	6262.0
LIPE	2527.0	415.0
LIPH	6214.0	-3120.0
LIPT1	-1997.0	-3803.0
LIPT2	5194.0	726.0
LMBRD1	4227.0	4468.0
LPCAT1	-6277.0	7035.0
LPCAT2	-3521.0	2634.0
LPCAT3	-6798.0	2880.0
LPCAT4	3374.0	1637.0
LPGAT1	-6932.0	-124.0
LPIN1	7239.0	4207.0
LPIN2	449.0	5095.0
LPIN3	6870.0	2606.0
LPL	-7356.0	1308.0
LRAT	-1726.0	2615.0
LRP1	7344.0	8465.0
LRP10	2327.0	-5417.0
LRP12	-6410.0	42.0
LRP2	-7179.0	-3908.0
LRP8	5099.0	707.0
LRPPRC	3831.0	6319.0
LSS	6406.0	-4282.0
LTA4H	-1869.0	3373.0
LTC4S	7946.0	2724.0
LUM	4367.0	7749.0
LYPLA1	-6790.0	7638.0
LYVE1	4432.0	4395.0
MAN2B1	-3804.0	-5934.0
MAN2B2	7538.0	-1460.0
MAN2C1	4870.0	-6628.0
MANBA	-5693.0	-5502.0
MAOA	3741.0	-492.0
MAOB	6986.0	3691.0
MAPKAPK2	-2527.0	4587.0
MARCKS	-1781.0	5038.0
MARS1	-1343.0	1975.0
MAT2A	-5779.0	2822.0
MAT2B	4842.0	-1317.0
MBOAT1	4595.0	-193.0
MBOAT2	3926.0	7192.0
MBOAT7	-6104.0	-4306.0
MBTPS1	-6525.0	-4354.0
MBTPS2	5009.0	5876.0
MCAT	1596.0	-4830.0
MCCC1	-5695.0	1708.0
MCCC2	-3022.0	-403.0
MCEE	1475.0	1452.0
MDH1	4402.0	4491.0
MDH2	3713.0	4456.0
ME1	-7337.0	4579.0
ME2	6693.0	6628.0
ME3	1300.0	-1217.0
MECR	113.0	-4655.0
MED1	-6294.0	6202.0
MED10	-216.0	6866.0
MED11	4114.0	-2523.0
MED12	2883.0	-4523.0
MED13	-6622.0	7554.0
MED13L	-1854.0	2715.0
MED14	-7065.0	3403.0
MED15	4680.0	-4482.0
MED16	7676.0	-3167.0
MED17	-3014.5	1170.5
MED18	-5417.0	3852.0
MED19	-3593.0	7428.0
MED20	2722.0	-6368.0
MED21	-6615.0	7431.0
MED22	6145.0	-4961.0
MED23	-5988.0	936.0
MED24	-491.0	-1343.0
MED25	5022.0	-6109.0
MED26	6356.5	-2626.5
MED27	1369.0	-4165.0
MED28	-6976.0	-959.0
MED29	-3922.0	157.0
MED30	6587.0	-3243.0
MED31	3971.0	1460.0
MED4	-102.0	4608.0
MED6	-95.0	5484.0
MED7	-2359.0	7513.0
MED8	-1103.0	4114.0
MED9	4897.0	-1301.0
MFSD2A	-3164.0	-1561.0
MGLL	8090.0	5435.0
MGST1	7252.0	4639.0
MGST2	-4131.0	-5072.0
MGST3	8217.0	479.0
MID1IP1	-3383.0	5984.0
MIGA1	768.0	-1462.0
MIGA2	6651.0	-3644.0
MINPP1	4325.0	-1237.0
MIOX	-2652.0	-1642.0
MLX	-4960.0	3919.0
MLXIPL	579.0	-6772.0
MLYCD	-6254.0	-1293.0
MMAA	-6584.0	4238.0
MMAB	6161.0	-4519.0
MMACHC	1165.0	5604.0
MMADHC	-5372.0	6261.0
MMS19	7591.0	-6460.0
MMUT	-4754.0	5281.0
MOCOS	5115.0	3471.0
MOCS1	7161.0	-2875.0
MOCS2	5139.0	7659.0
MOCS3	286.0	-5607.0
MOGAT1	-6667.0	1116.0
MOGAT2	8164.0	-3178.0
MORC2	957.0	-3290.0
MPC1	-3373.0	8178.0
MPC2	5946.0	-6209.0
MPST	2510.0	-459.0
MRI1	7127.0	-6637.0
MSMO1	1100.0	3331.0
MT-ATP6	-5818.0	8744.0
MT-ATP8	3277.0	6153.0
MT-CO1	6781.0	5983.0
MT-CO2	293.0	-1711.0
MT-CO3	2273.0	6269.0
MT-CYB	3577.0	8110.0
MT-ND1	5618.0	7323.0
MT-ND2	-1693.0	8626.0
MT-ND3	1835.0	8689.0
MT-ND4	1752.0	7883.0
MT-ND5	6025.0	8007.0
MT-ND6	5059.0	8045.0
MTAP	-2386.0	7629.0
MTARC1	7812.5	4992.5
MTARC2	7913.0	384.0
MTF1	-4371.0	-3922.0
MTHFD1	7003.0	2637.0
MTHFD1L	8010.0	4024.0
MTHFD2	741.0	6092.0
MTHFD2L	5275.0	1578.0
MTHFR	-7138.0	-2908.0
MTHFS	179.5	-3965.5
MTM1	681.0	2456.0
MTMR1	-877.0	7128.0
MTMR10	-3407.0	6392.0
MTMR12	-4933.0	6552.0
MTMR14	7277.0	-5621.0
MTMR2	-3290.0	8642.0
MTMR3	-3717.0	2706.0
MTMR4	-7122.0	399.0
MTMR6	-5050.0	7595.0
MTMR7	-3620.0	-4213.0
MTMR9	6867.0	178.0
MTR	-7154.0	-1156.0
MTRR	-1959.0	968.0
MVD	-6321.0	-3670.0
MVK	7491.0	-2189.0
N6AMT1	6423.0	2373.0
NAALAD2	-6544.0	8116.0
NADK	-6297.0	3878.0
NADK2	321.0	721.0
NADSYN1	6875.0	-6478.0
NAGLU	-4620.0	-6515.0
NAMPT	8078.0	8082.0
NAPRT	3730.0	-6610.0
NAT1	-1582.5	7350.5
NAT2	-1582.5	7350.5
NAT8L	-2487.0	2131.0
NAXD	-5354.0	4484.0
NAXE	5027.0	-541.0
NCAN	1112.0	-3927.0
NCOA1	-3434.0	7005.0
NCOA2	-5757.0	5994.0
NCOA3	-4267.0	2629.0
NCOA6	-4607.0	8043.0
NCOR1	-7262.0	6244.0
NCOR2	-225.0	-3484.0
NDC1	6665.0	-1084.0
NDOR1	7585.0	-6564.0
NDST1	6876.0	-2809.0
NDST2	6614.5	-5673.5
NDST3	-4105.0	-41.0
NDST4	1551.0	-6476.0
NDUFA1	2104.0	-4989.0
NDUFA10	-1891.0	7765.0
NDUFA11	7279.5	474.5
NDUFA12	4539.0	8087.0
NDUFA13	4768.0	-2346.0
NDUFA2	5261.0	-6155.0
NDUFA3	4319.0	82.0
NDUFA4	-5102.0	8096.0
NDUFA5	7846.0	2875.0
NDUFA6	6990.0	5257.0
NDUFA7	7477.5	4100.5
NDUFA8	5308.0	4366.0
NDUFA9	3756.0	-5331.0
NDUFAB1	251.0	2742.0
NDUFAF1	-5470.0	1013.0
NDUFAF2	-2453.0	6013.0
NDUFAF3	-983.0	-2862.0
NDUFAF4	-5532.0	7346.0
NDUFAF5	1712.0	1907.0
NDUFAF6	-2110.0	-2934.0
NDUFAF7	1694.0	6697.0
NDUFB1	5672.0	711.0
NDUFB10	4853.0	-1340.0
NDUFB11	1539.0	7247.0
NDUFB2	2034.0	-5126.0
NDUFB3	-2553.0	-4632.0
NDUFB4	-5247.0	8719.0
NDUFB5	450.0	2312.0
NDUFB6	6783.0	848.0
NDUFB7	5336.0	2347.0
NDUFB8	4901.5	6790.5
NDUFB9	6765.0	1224.0
NDUFC1	1620.0	3968.0
NDUFC2	4564.5	-5546.5
NDUFS1	-1094.0	6402.0
NDUFS2	1841.0	4991.0
NDUFS3	4184.0	-2145.0
NDUFS4	4791.0	4043.0
NDUFS5	5126.0	-4249.0
NDUFS6	2287.0	6500.0
NDUFS7	7367.0	-5947.0
NDUFS8	1961.0	2910.0
NDUFV1	4313.0	-2431.0
NDUFV2	4127.0	8731.0
NDUFV3	-5257.0	5625.0
NEU1	-4896.0	-6581.0
NEU2	-5135.0	4638.0
NEU3	5534.0	4644.0
NFS1	-5435.0	-3055.0
NFYA	-6056.0	1269.0
NFYB	4475.0	-1375.0
NFYC	5234.0	-4754.0
NHLRC1	670.0	-3827.0
NME1	-2685.0	-1279.0
NME2	-3826.0	-2887.0
NME3	-6171.0	-3785.0
NME4	5621.0	-5851.0
NMNAT1	-2557.0	6042.0
NMNAT2	-976.0	1199.0
NMNAT3	-1019.0	-6435.0
NMRAL1	918.0	-1415.0
NMRK1	5206.0	-2401.0
NMRK2	2766.0	-4346.0
NNMT	-1112.0	7138.0
NNT	4576.0	4716.0
NOS3	1400.0	2054.0
NOSIP	4944.0	-2035.0
NOSTRIN	-5504.0	6787.0
NPAS2	-7180.0	4077.0
NQO1	8179.0	2951.0
NQO2	-3239.0	2309.0
NR1D1	4829.0	-176.0
NR1H2	3611.0	-4559.0
NR1H3	-6285.0	1226.0
NR1H4	6851.0	5380.0
NRF1	-4406.0	5203.0
NSDHL	6403.0	-1274.0
NT5C	1711.0	7165.0
NT5C1A	6349.0	695.0
NT5C1B	4970.5	-3744.5
NT5C2	3184.0	2093.0
NT5C3A	-6755.0	3398.0
NT5E	-7042.0	7643.0
NT5M	4046.0	-5105.0
NUBP1	6858.0	-1573.0
NUBP2	1692.0	509.0
NUBPL	-1636.0	-1999.0
NUDT1	1820.0	-5375.0
NUDT11	-5174.0	-1010.0
NUDT12	-6633.0	6194.0
NUDT13	4909.0	-6288.0
NUDT15	-2671.0	147.0
NUDT16	5782.0	-2852.0
NUDT18	1357.0	-3593.0
NUDT19	-7277.0	3469.0
NUDT3	-104.0	2864.0
NUDT4	5597.5	4066.5
NUDT5	-3967.0	5396.0
NUDT7	6934.0	4270.0
NUDT9	-540.0	4482.0
NUP107	3423.0	7169.0
NUP133	2759.0	-4113.0
NUP153	-4638.0	7763.0
NUP155	6347.0	2192.0
NUP160	-5230.0	1753.0
NUP188	3880.0	-4145.0
NUP205	855.0	6303.0
NUP210	8193.0	-4172.0
NUP214	7802.0	-5326.0
NUP35	-4374.0	-921.0
NUP37	3596.0	1004.0
NUP42	4998.0	-596.0
NUP43	-2270.0	3764.0
NUP50	-4961.0	641.0
NUP54	-3355.0	6010.0
NUP58	2230.0	7116.0
NUP62	4963.0	-4765.0
NUP85	1103.0	-4750.0
NUP88	4817.0	4002.0
NUP93	5331.0	6196.0
NUP98	-2590.0	5122.0
OAT	7204.0	1107.0
OAZ1	-1929.0	-128.0
OAZ2	-4424.0	-3557.0
OAZ3	-3416.0	-3824.0
OCRL	3974.0	593.0
ODC1	-7155.0	3068.0
OGDH	6393.0	3583.0
OGN	550.0	8729.0
OMD	-5697.0	7722.0
OPLAH	8134.0	-4469.0
ORMDL1	-1026.0	-2289.0
ORMDL2	-5602.0	-556.0
ORMDL3	5642.0	-2453.0
OSBP	-275.0	7493.0
OSBPL10	-2744.0	-243.0
OSBPL1A	6468.0	6678.0
OSBPL2	388.0	6106.0
OSBPL3	-6478.0	-6299.0
OSBPL5	8172.0	-173.0
OSBPL6	5277.0	1248.0
OSBPL7	6957.0	-5698.0
OSBPL8	-6712.0	2507.0
OSBPL9	-2057.0	7863.0
OXCT1	-7285.0	3031.0
OXCT2	7349.0	3443.0
PAH	-6037.0	-1280.0
PAICS	-2433.0	5813.0
PANK1	-3898.0	3887.0
PANK2	-4802.0	-2608.0
PANK3	6457.0	7664.0
PANK4	-26.0	-4629.0
PAOX	7993.5	-5253.5
PAPSS1	-2058.0	4960.0
PAPSS2	7044.0	-2227.0
PARP10	7711.0	-4684.0
PARP14	-5054.0	4222.0
PARP16	1718.0	-2509.0
PARP4	6474.0	-716.0
PARP6	3375.0	4640.0
PARP8	-7014.0	-116.0
PARP9	-2628.0	513.0
PC	-4135.0	-1520.0
PCBD1	-3277.0	5173.0
PCCA	-6893.0	5127.0
PCCB	1319.0	4303.0
PCK1	6911.0	5688.0
PCK2	7209.0	-2828.0
PCTP	1119.0	3046.0
PCYT1A	-4534.0	7622.0
PCYT1B	1457.0	-4294.0
PCYT2	-6251.0	-6210.0
PDHA1	-16.0	7978.0
PDHB	182.0	8175.0
PDHX	-1471.0	7544.0
PDK1	8236.0	5206.0
PDK2	8043.0	-1425.0
PDK3	-7135.0	6177.0
PDK4	3864.0	4092.0
PDP1	4298.0	7517.0
PDP2	-1525.0	-1465.0
PDPR	-1560.0	-1589.0
PDSS1	-6044.0	4425.0
PDSS2	-5663.0	83.0
PDXK	8266.0	-2949.0
PDZD11	-3180.0	64.0
PECR	-7227.0	-2923.0
PEMT	4391.0	-6096.0
PEX11A	4523.0	6264.0
PFAS	7341.0	-6233.0
PFKFB1	6378.0	-1147.0
PFKFB2	3501.0	-6523.0
PFKFB3	7737.0	7129.0
PFKFB4	7536.0	3222.0
PFKL	7340.0	-4515.0
PFKM	5220.0	-2428.0
PFKP	2927.0	2961.0
PGAM1	1992.0	4530.0
PGAM2	7034.0	6971.0
PGD	7610.0	2865.0
PGK1	-656.0	7226.0
PGLS	7748.0	-4404.0
PGM1	-1081.0	5048.0
PGM2	7401.0	7591.0
PGM2L1	4235.0	7460.0
PGP	-2129.0	-1371.0
PGS1	-5541.0	-1350.0
PHGDH	-2912.0	-42.0
PHKA1	-967.0	3541.0
PHKA2	5251.0	-5498.0
PHKB	-6642.0	4537.0
PHKG1	4096.0	-1199.0
PHKG2	-2231.0	4887.0
PHOSPHO1	5210.0	4747.0
PHYH	-2082.0	7439.0
PHYKPL	6056.0	-4936.0
PI4K2A	-4599.5	199.5
PI4K2B	7665.0	6942.0
PI4KA	-7242.0	1626.0
PI4KB	-1235.0	-2651.0
PIAS4	1983.0	-5993.0
PIK3C2A	-262.0	8592.0
PIK3C2B	6591.0	344.0
PIK3C2G	-1661.0	-4735.0
PIK3C3	1518.0	-2612.0
PIK3CA	-6347.0	2923.0
PIK3CB	-1756.0	1880.0
PIK3CD	-1968.0	1889.0
PIK3CG	-5373.0	8065.0
PIK3R1	-839.0	8363.0
PIK3R2	1669.5	-3969.5
PIK3R3	3779.5	8820.5
PIK3R4	4272.0	-1214.0
PIK3R5	-1994.0	2879.0
PIK3R6	-2176.0	1075.0
PIKFYVE	-3207.0	3920.0
PIP4K2A	-1245.0	7145.0
PIP4K2B	-937.0	1458.0
PIP4K2C	7615.0	-1511.0
PIP5K1A	-1663.0	5148.0
PIP5K1B	4665.0	2907.0
PIP5K1C	6778.0	694.0
PIPOX	-966.0	1121.0
PISD	-1467.0	-6282.0
PITPNB	-1856.0	7578.0
PITPNM1	6925.0	-4076.0
PITPNM2	6797.0	-3577.0
PITPNM3	7459.0	-3839.0
PKLR	8195.0	-127.0
PKM	7561.0	7758.0
PLA1A	6531.0	1813.0
PLA2G10	1749.0	-3798.0
PLA2G12A	7010.0	5563.0
PLA2G15	4841.0	431.0
PLA2G2D	-2886.0	4341.0
PLA2G3	-1601.0	-6363.0
PLA2G4A	7058.0	5276.0
PLA2G4B	-2563.5	-6753.5
PLA2G4C	2782.0	-1937.0
PLA2G4E	-1194.0	-2351.0
PLA2G5	3897.0	-2765.0
PLA2G6	-5964.0	-5304.0
PLA2R1	-6067.0	7483.0
PLAAT1	7024.0	3716.0
PLAAT3	8081.0	3057.0
PLB1	-5117.0	-4633.0
PLBD1	-389.0	-1566.0
PLCB1	953.0	1207.0
PLCB2	-6204.0	487.0
PLCB3	717.0	1778.0
PLCB4	7393.0	7817.0
PLCD1	5021.0	2747.0
PLCD3	-2156.0	-1373.0
PLCD4	4775.0	5641.0
PLCE1	6100.0	6421.0
PLCG1	8067.0	-4962.0
PLCG2	-5287.0	2474.0
PLCH1	7745.0	-2585.0
PLCH2	-768.0	4954.0
PLD1	-4824.0	-1222.0
PLD2	-309.0	-2778.0
PLD3	5879.0	-2713.0
PLD4	-6072.0	4205.0
PLD6	3992.0	-4236.0
PLEKHA1	4350.0	-2221.0
PLEKHA2	-2392.0	6015.0
PLEKHA3	-761.0	8002.0
PLEKHA4	3114.0	-4509.0
PLEKHA5	1412.0	1657.0
PLEKHA6	-6372.0	-4695.0
PLEKHA8	-4985.0	5653.0
PLIN1	-3309.0	-4723.0
PLIN2	3994.0	4652.0
PLIN3	5004.0	-4323.0
PLPP1	6991.0	7651.0
PLPP2	4535.0	-6126.0
PLPP3	-2151.0	8260.0
PLPP6	-22.0	-5281.0
PM20D1	-4304.0	-1376.0
PMVK	6667.0	-5342.0
PNP	-7335.0	8459.0
PNPLA2	7942.0	833.0
PNPLA3	-4748.0	4527.0
PNPLA6	-3845.0	-5609.0
PNPLA7	6339.0	-3528.0
PNPLA8	1483.0	7253.0
PNPO	4729.0	-351.0
PODXL2	4685.0	-2746.0
POLD1	4995.0	-5596.0
POM121	3732.5	-6552.5
POM121C	3732.5	-6552.5
POMC	3685.0	-2222.0
PON2	-6815.0	8005.0
PON3	-4388.0	6757.0
POR	5792.0	1518.0
PPA1	4412.0	6506.0
PPA2	-5134.0	6061.0
PPARA	7841.0	-6419.0
PPARD	-6955.0	-1980.0
PPARG	-3636.0	5654.0
PPARGC1A	7867.0	2494.0
PPARGC1B	6696.0	-5924.0
PPAT	6637.0	6980.0
PPCDC	-2591.0	-6547.0
PPCS	-5401.0	6356.0
PPIP5K1	6197.0	1267.0
PPIP5K2	-4934.0	1658.0
PPM1K	6256.0	-5826.0
PPM1L	-6216.0	1133.0
PPOX	5140.0	-6533.0
PPP1CA	3276.0	-19.0
PPP1CB	-4617.0	8661.0
PPP1CC	6108.0	2839.0
PPP1R3C	6926.0	-1003.0
PPP2CA	-5725.0	8237.0
PPP2CB	5588.0	159.0
PPP2R1A	6355.0	3115.0
PPP2R1B	-6463.0	4855.0
PPP2R5D	2088.0	5911.0
PPT1	-6393.0	5633.0
PPT2	-5191.5	-2667.5
PRELP	4400.0	8732.0
PRKAA2	-1063.0	2375.0
PRKAB2	4730.0	-4503.0
PRKACA	-530.0	15.0
PRKACB	569.0	661.0
PRKAG2	7790.0	-3443.0
PRKAR1A	3942.0	6647.0
PRKAR1B	6901.0	5113.0
PRKAR2A	5319.0	7462.0
PRKAR2B	-2382.0	-990.0
PRKCA	-6271.0	3380.0
PRKD1	-339.0	4350.0
PRKD2	5276.0	1085.0
PRKD3	-7282.0	6753.0
PRKG2	1125.0	-4521.0
PRODH	6792.5	-2080.5
PRODH2	7962.0	-5825.0
PRPS1	-6688.0	3956.0
PRPS2	4305.0	6330.0
PRSS1	-2444.0	-3110.0
PRSS3	-2444.0	-3110.0
PRXL2B	187.0	-4990.0
PSAP	6220.0	-3472.0
PSAT1	-6634.0	6004.0
PSMA1	-6705.0	7838.0
PSMA2	-5464.5	6058.5
PSMA3	-3145.0	7801.0
PSMA4	-6074.0	4688.0
PSMA5	-6660.0	4497.0
PSMA6	-1954.0	8445.0
PSMA7	1612.0	7052.0
PSMA8	649.0	-4004.0
PSMB1	-5281.0	5936.0
PSMB10	3752.0	-908.0
PSMB11	1977.0	-5501.0
PSMB2	1472.0	-4144.0
PSMB3	-3388.0	5539.0
PSMB4	-4941.0	-5852.0
PSMB5	-1638.0	-2409.0
PSMB6	1806.0	-1845.0
PSMB7	-4628.0	-657.0
PSMB8	1080.0	-3793.0
PSMB9	5987.0	-4708.0
PSMC1	-1312.0	4327.0
PSMC2	-6765.0	4648.0
PSMC3	-4285.0	3386.0
PSMC4	-6423.0	7920.0
PSMC5	-4831.0	1120.0
PSMC6	-6851.0	8666.0
PSMD1	-6497.0	8619.0
PSMD10	-1613.0	2576.0
PSMD11	-6873.0	5201.0
PSMD12	-6149.0	8628.0
PSMD13	1898.0	5044.0
PSMD14	-6080.0	8262.0
PSMD2	-6702.0	-3836.0
PSMD3	-2532.0	-3242.0
PSMD4	-5648.0	4994.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
PSMD7	-6943.0	7625.0
PSMD8	1978.0	7546.0
PSMD9	7707.5	-894.5
PSME1	2907.0	5905.0
PSME2	1270.0	-4595.0
PSME3	752.0	7366.0
PSME4	-6830.0	8511.0
PSMF1	5087.0	4771.0
PSPH	5326.0	684.0
PSTK	1158.0	-5748.0
PTDSS1	-1647.0	572.0
PTDSS2	7115.0	-3765.0
PTEN	-5726.0	8365.0
PTGDS	4285.5	-1738.5
PTGES	4924.0	5468.0
PTGES2	5575.0	-1828.0
PTGES3	-7067.0	8733.0
PTGIS	7164.0	6579.0
PTGR1	2116.0	-1873.0
PTGR2	-1029.5	2387.5
PTGS1	5729.0	6228.0
PTGS2	-2970.0	5783.0
PTPMT1	6917.0	6060.0
PTPN13	-3702.0	-4340.0
PTS	2598.0	-1351.0
PXMP2	7014.0	-4010.0
PYCR1	-1242.0	-3991.0
PYCR2	6149.5	-3160.5
PYGB	5808.0	5273.0
PYGL	6729.0	1748.0
PYGM	-3631.0	5299.0
QARS1	-2466.0	-794.0
QDPR	3954.0	-2266.0
QPRT	-1641.0	-5809.0
RAB14	-4203.0	5569.0
RAB4A	-4186.0	1766.0
RAB5A	1537.0	7332.0
RAE1	3041.0	-1934.0
RAN	-4369.0	1437.0
RANBP2	-4575.0	8132.0
RAP1A	-6787.0	8805.0
RAPGEF3	6998.0	-5986.0
RAPGEF4	-2613.0	5313.0
RARS1	-4439.0	6407.0
RBKS	4889.0	5719.0
RBP1	-60.0	5045.0
RBP2	5046.0	-1992.0
RBP4	5187.0	5087.0
RDH11	870.5	5420.5
RETSAT	6784.0	540.0
RFK	6308.0	3308.0
RGL1	-6436.0	-5685.0
RIDA	-577.0	5347.0
RIMKLA	6286.0	6084.0
RIMKLB	-1155.0	2941.0
RNLS	547.0	-5179.0
RORA	-3317.0	3869.0
RPE	-5245.5	8014.5
RPEL1	-5245.5	8014.5
RPIA	-2267.0	-1161.0
RPL11	5748.0	1403.0
RPL12	6107.0	-5604.0
RPL13	5686.0	-3760.0
RPL14	5110.0	-1875.0
RPL18	2523.0	-625.0
RPL18A	4545.0	-3218.0
RPL19	4654.0	6782.0
RPL21	-1686.0	8463.0
RPL22	2365.0	459.0
RPL22L1	-5123.0	-6294.0
RPL23	-205.0	4253.0
RPL24	-409.0	6813.0
RPL26	3650.0	8722.0
RPL28	6714.0	4753.0
RPL29	2613.0	4628.0
RPL3	5378.0	1155.0
RPL30	4372.0	3664.0
RPL31	6732.0	-1507.0
RPL32	2989.0	8728.0
RPL34	661.0	7140.0
RPL35	5949.0	8834.0
RPL35A	-1509.0	6565.0
RPL36	7543.0	-2424.0
RPL36A	-5983.0	4837.0
RPL36AL	1793.0	-2074.0
RPL37	2109.0	-667.0
RPL38	5601.0	5675.0
RPL3L	-5986.0	4937.0
RPL4	2582.0	8471.0
RPL6	572.0	7594.0
RPL7	-5186.0	8598.0
RPL8	3526.0	820.0
RPLP2	3550.0	3555.0
RPS13	7174.0	315.0
RPS14	4070.0	4443.0
RPS15	7253.0	6174.0
RPS16	6244.0	1119.0
RPS17	5667.0	7685.0
RPS18	4253.0	-526.0
RPS19	6565.0	-1215.0
RPS2	7322.0	4216.0
RPS21	7111.0	-6494.0
RPS25	4261.0	8455.0
RPS27A	-133.0	-1807.0
RPS28	7208.0	-396.0
RPS3	2340.0	4381.0
RPS3A	-3115.0	8824.0
RPS4X	2522.0	7391.0
RPS5	3848.0	7515.0
RPS6	-1700.0	8603.0
RPS8	3874.0	7646.0
RPS9	-1719.0	-2555.0
RRM1	6191.0	2597.0
RRM2	5536.0	5080.0
RRM2B	-3558.0	6819.0
RTEL1	5543.5	-4539.5
RUFY1	-803.0	3857.0
RXRA	-5143.0	1552.0
RXRB	-1930.0	-6196.0
SACM1L	643.0	5177.0
SAMD8	-6523.0	2366.0
SAMHD1	1852.0	601.0
SAR1B	-3423.0	7668.0
SARDH	1157.0	-5594.0
SARS1	-2185.0	3720.0
SAT1	5606.0	7029.0
SBF1	5827.0	-6278.0
SBF2	7073.0	3902.0
SC5D	-4583.0	-1271.0
SCAP	5754.0	-4415.0
SCD	-3146.0	4477.0
SCLY	-3044.0	-4667.0
SCO1	-3365.0	57.0
SCO2	-3687.0	2948.0
SCP2	-5228.0	1141.0
SDC1	6076.0	6227.0
SDC2	-6850.0	7623.0
SDC3	5919.0	4486.0
SDC4	6585.0	816.0
SDHA	3626.5	-1630.5
SDHB	3180.0	7355.0
SDHC	-860.0	834.0
SDHD	6887.5	1213.5
SDSL	1517.0	-3636.0
SEC13	-1432.0	3604.0
SEC23A	-3552.0	8413.0
SEC24A	159.0	5121.0
SEC24B	-570.0	-3344.0
SEC24C	-5965.0	-1916.0
SEC24D	-6384.0	8428.0
SECISBP2	-1563.0	-4146.0
SEH1L	2204.0	6910.0
SELENOI	85.0	-4378.0
SEPHS2	5549.0	2094.0
SEPSECS	-861.0	-2800.0
SERINC1	-5903.0	6313.0
SERINC2	-7090.0	-1593.0
SERINC3	-4809.0	7490.0
SERINC4	-2075.0	8337.0
SERINC5	7586.0	448.0
SGMS1	-3278.0	3419.0
SGMS2	6340.0	1814.0
SGPL1	4743.0	1318.0
SGPP1	5306.0	4073.0
SGPP2	-1603.0	2521.0
SGSH	-3029.0	-5401.0
SHMT1	7861.0	3150.0
SHMT2	3234.0	-1545.0
SHPK	7652.5	1343.5
SIN3A	4581.0	6116.0
SIN3B	6970.0	-4759.0
SLC10A1	-6239.0	175.0
SLC10A2	-2003.0	2069.0
SLC16A1	-7027.0	5763.0
SLC16A3	5619.0	-3522.0
SLC16A8	87.0	-4934.0
SLC19A1	4798.0	-4123.0
SLC19A2	8115.0	5261.0
SLC19A3	-5011.0	7302.0
SLC22A1	2086.0	-2665.0
SLC22A13	6196.0	-2872.0
SLC22A2	-6841.0	-2507.0
SLC22A3	7801.0	1174.0
SLC22A5	7906.0	-6776.0
SLC23A1	7728.0	-3846.0
SLC23A2	6961.0	3743.0
SLC25A1	3746.0	544.0
SLC25A10	6761.5	-5719.5
SLC25A11	5582.0	-2414.0
SLC25A12	7967.0	4933.0
SLC25A13	3242.0	999.0
SLC25A14	-1689.0	-3486.0
SLC25A15	-6152.0	-1607.0
SLC25A16	7887.0	3899.0
SLC25A17	6111.0	-583.0
SLC25A19	-6509.0	-3313.0
SLC25A2	-5119.0	2452.0
SLC25A20	6499.0	4961.0
SLC25A21	-6972.0	-4672.0
SLC25A27	1702.0	-2334.0
SLC25A28	6443.0	-3623.0
SLC25A32	3679.5	5195.5
SLC25A37	4308.0	6003.0
SLC25A44	2179.0	2707.0
SLC26A1	-5232.0	-2254.0
SLC26A2	4919.0	406.0
SLC27A1	8097.0	-6566.0
SLC27A2	-6940.0	532.0
SLC27A3	3921.0	-3608.0
SLC27A5	245.0	-4504.0
SLC2A1	6575.0	1160.0
SLC2A2	7902.0	2301.0
SLC35B2	-2165.0	-29.0
SLC35B3	3014.0	-138.0
SLC35D1	7505.0	-5061.0
SLC35D2	909.5	-231.5
SLC36A4	7632.0	5156.0
SLC37A1	6725.0	-4214.0
SLC37A2	-5241.0	4444.0
SLC37A4	5992.0	2463.0
SLC3A2	7436.0	1396.0
SLC44A1	2354.0	3189.0
SLC44A2	7940.0	4899.0
SLC44A3	4991.0	6747.0
SLC44A4	-6797.0	-4935.0
SLC44A5	-1451.0	-3029.0
SLC46A1	-3579.0	-3647.0
SLC52A2	-6134.0	-6313.0
SLC52A3	-5691.0	-1604.0
SLC5A6	8182.0	-5096.0
SLC5A8	-239.0	6301.0
SLC6A12	6159.0	-1426.0
SLC6A8	7995.5	-5854.5
SLC7A5	6666.0	-84.0
SLC9A1	7851.0	-5503.0
SLCO1A2	-7358.0	8708.0
SLCO2B1	5189.0	7400.0
SMARCD3	7045.0	3943.0
SMOX	-1362.0	-56.0
SMPD1	-4913.0	-5120.0
SMPD2	-2964.0	-4780.0
SMPD3	331.0	-3904.0
SMPD4	2797.0	-2867.0
SMS	-3659.0	7778.0
SORD	3112.0	841.0
SP1	571.0	4734.0
SPHK1	6446.0	-1574.0
SPHK2	-1993.0	-4224.0
SPNS2	7955.0	516.0
SPR	-3932.0	-5850.0
SPTLC1	-6882.0	-1550.0
SPTLC2	-735.0	-2873.0
SPTLC3	-5207.0	1078.0
SPTSSA	-4193.0	5522.0
SPTSSB	-1534.0	2326.0
SQLE	6213.0	3809.0
SRD5A1	564.0	-1319.0
SRD5A2	-7151.0	-4218.0
SRD5A3	-2854.0	4649.0
SREBF1	-2758.0	-4433.0
SREBF2	4102.0	-4553.0
SRM	-235.0	-2454.0
SRR	-5380.0	7655.0
ST3GAL1	3065.0	8669.0
ST3GAL2	6089.0	121.0
ST3GAL3	-3090.0	3648.0
ST3GAL4	-1264.0	1193.0
ST3GAL6	774.0	7961.0
ST6GALNAC6	4180.5	5612.5
STAB2	3055.0	-2320.0
STAR	5397.0	-4980.0
STARD10	-4413.0	5012.0
STARD3	-3871.0	-6390.0
STARD3NL	-4101.0	-5083.0
STARD4	7421.0	2973.0
STARD5	7176.0	-4794.0
STARD6	2813.0	1709.0
STARD7	4852.0	-861.0
STK11	1350.0	-4303.0
STX1A	2774.0	-2559.0
STXBP1	2263.0	7786.0
SUCLA2	-5284.0	8723.0
SUCLG1	1641.0	7641.0
SUCLG2	2515.0	3596.0
SULT1A1	3145.5	-3951.5
SULT1A2	3145.5	-3951.5
SULT1A3	3145.5	-3951.5
SULT1A4	3145.5	-3951.5
SULT1B1	-5220.0	6351.0
SULT1C2	223.0	23.0
SULT2A1	-3150.0	872.0
SULT2B1	-444.0	1281.0
SULT6B1	1651.0	-2186.0
SUMF1	-6426.0	292.0
SUMO2	-2663.5	8652.5
SUOX	6862.0	-1063.0
SURF1	2134.0	4131.0
SYNJ1	2013.0	4478.0
SYNJ2	3594.0	6905.0
TACO1	-3888.0	3315.0
TALDO1	-5386.0	449.0
TAZ	4420.0	-6361.0
TBL1X	-7106.5	7510.5
TBL1XR1	-1156.0	6145.0
TBXAS1	-7074.0	-5151.0
TCN2	-6559.0	2042.0
TDO2	1826.0	-521.0
TECR	1529.0	-251.0
TGS1	-5959.0	7769.0
THEM4	-3393.0	6155.0
THRAP3	6727.0	760.0
THRSP	2670.0	6433.0
THTPA	-1903.0	-2214.0
TIAM2	-5202.0	-5050.0
TIMMDC1	-2651.0	-2924.0
TK1	-494.0	-991.0
TK2	7046.0	-155.0
TKFC	5898.0	1211.0
TKT	8181.0	2150.0
TM7SF2	6864.0	-1250.0
TMEM126B	-6725.0	3713.0
TMEM86B	2421.0	-5639.0
TNFAIP8	2993.0	-2273.0
TNFAIP8L1	-707.0	2884.0
TNFAIP8L2	-2438.0	5608.0
TNFAIP8L3	6935.0	-799.0
TNFRSF21	7819.0	3310.0
TPK1	-6759.0	3853.0
TPMT	-2094.0	4118.0
TPR	-4239.0	8611.0
TPST1	-1632.0	2591.0
TPST2	5077.0	-171.0
TPTE	-5920.5	6543.5
TPTE2	-5920.5	6543.5
TRAP1	-6124.0	2675.0
TRIB3	3661.0	-614.0
TRMT112	-6614.0	-1009.0
TSHB	5602.0	-4369.0
TSPO	4875.0	-4150.0
TSPOAP1	3785.0	-6302.0
TST	2727.0	-5857.0
TSTD1	4358.0	-4018.0
TTPA	-54.0	8298.0
TTR	-6090.0	3451.0
TXN	-5397.0	-2909.0
TXN2	-2656.0	1641.0
TXNRD1	-3425.0	4896.0
TYMP	5612.0	-6441.0
TYMS	7313.0	-3739.0
TYR	1845.0	-4177.0
UBA52	7488.0	-4269.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
UBE2I	5599.0	2810.0
UBIAD1	-7131.0	-1709.0
UCK1	4426.0	607.0
UCK2	4470.0	6711.0
UCKL1	3359.0	-5927.0
UCP2	6987.0	4595.0
UCP3	3545.0	-4364.0
UGCG	-6237.0	4297.0
UGDH	7487.0	4096.0
UGP2	-6121.0	8636.0
UGT1A1	8194.0	-551.0
UGT1A10	8268.5	-6174.5
UGT1A3	8254.0	-5328.0
UGT1A4	8254.0	-5328.0
UGT1A5	8254.0	-5328.0
UGT1A6	-1567.0	-5689.0
UGT1A7	8268.5	-6174.5
UGT1A8	8268.5	-6174.5
UGT1A9	8268.5	-6174.5
UGT2A2	4001.0	290.0
UGT2A3	-6867.0	-5535.0
UGT3A2	-7338.0	5454.0
UGT8	-7116.0	4552.0
UMPS	4556.0	-2755.0
UPB1	7323.0	2972.0
UPP1	5774.0	8231.0
UPP2	7868.0	2949.0
UQCR10	6187.0	697.0
UQCR11	5012.5	-3179.5
UQCRB	-410.0	8334.0
UQCRC1	5627.0	1729.0
UQCRC2	2236.0	6852.0
UQCRFS1	3296.0	-3981.0
UQCRH	5780.5	-5189.5
UQCRQ	6271.0	7840.0
UROC1	7758.0	-257.0
UROD	3363.0	-369.0
UROS	-6901.0	-1074.0
UST	1403.0	7122.0
VAC14	-3671.0	-1173.0
VAMP2	8086.5	-3275.5
VAPA	-4422.0	7382.0
VAPB	-5456.0	1793.0
VCAN	-3773.0	1454.0
VDAC1	6.0	6549.0
VDR	3336.0	-653.0
VKORC1	-5730.0	-1093.0
VKORC1L1	636.0	6265.0
VNN1	6246.0	7250.0
WASL	-3989.0	7855.0
XDH	8158.0	1436.0
XYLB	-5444.0	-1834.0
XYLT1	-6376.0	-5032.0
XYLT2	7644.0	-5845.0
ZDHHC21	-4110.0	5505.0

---

---

GTP hydrolysis and joining of the 60S ribosomal subunit

GTP hydrolysis and joining of the 60S ribosomal subunit

metric	value
setSize	78
pMANOVA	3.66e-10
p.adjustMANOVA	1.97e-08
s.dist	0.39
s.diabetes	0.175
s.mitoG	0.349
p.diabetes	0.00775
p.mitoG	1e-07

Top 20 genes

Gene	diabetes	mitoG
RPL35	5949.0	8834.0
FAU	6809.0	7710.0
RPS15	7253.0	6174.0
RPS17	5667.0	7685.0
RPS25	4261.0	8455.0
RPL28	6714.0	4753.0
RPL26	3650.0	8722.0
RPL38	5601.0	5675.0
RPL19	4654.0	6782.0
RPS2	7322.0	4216.0
RPS8	3874.0	7646.0
RPS5	3848.0	7515.0
EIF3K	4728.0	6062.0
RPL32	2989.0	8728.0
EIF3L	5174.0	4824.0
EIF3C	4964.5	4995.5
RPL4	2582.0	8471.0
RPS4X	2522.0	7391.0
RPS14	4070.0	4443.0
RPL30	4372.0	3664.0

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
EIF2S1	-4830.0	8741.0
EIF2S2	-3307.0	8799.0
EIF2S3	-2819.5	4900.5
EIF3A	-4951.0	8381.0
EIF3B	-286.0	3875.0
EIF3C	4964.5	4995.5
EIF3D	511.0	8172.0
EIF3E	-4677.0	8580.0
EIF3F	2793.0	1790.0
EIF3G	836.0	1475.0
EIF3H	-4343.0	8629.0
EIF3I	5694.0	2343.0
EIF3J	-4890.0	8838.0
EIF3K	4728.0	6062.0
EIF3L	5174.0	4824.0
EIF3M	-2954.0	7258.0
EIF4A1	5335.0	61.0
EIF4A2	-6848.0	-699.0
EIF4B	-4266.0	-945.0
EIF4E	-4500.0	8429.0
EIF4G1	-5996.0	5731.0
EIF4H	5370.0	-98.0
EIF5	-1683.0	7276.0
EIF5B	-1780.0	8616.0
FAU	6809.0	7710.0
RPL11	5748.0	1403.0
RPL12	6107.0	-5604.0
RPL13	5686.0	-3760.0
RPL14	5110.0	-1875.0
RPL18	2523.0	-625.0
RPL18A	4545.0	-3218.0
RPL19	4654.0	6782.0
RPL21	-1686.0	8463.0
RPL22	2365.0	459.0
RPL22L1	-5123.0	-6294.0
RPL23	-205.0	4253.0
RPL24	-409.0	6813.0
RPL26	3650.0	8722.0
RPL28	6714.0	4753.0
RPL29	2613.0	4628.0
RPL3	5378.0	1155.0
RPL30	4372.0	3664.0
RPL31	6732.0	-1507.0
RPL32	2989.0	8728.0
RPL34	661.0	7140.0
RPL35	5949.0	8834.0
RPL35A	-1509.0	6565.0
RPL36	7543.0	-2424.0
RPL36A	-5983.0	4837.0
RPL36AL	1793.0	-2074.0
RPL37	2109.0	-667.0
RPL38	5601.0	5675.0
RPL3L	-5986.0	4937.0
RPL4	2582.0	8471.0
RPL6	572.0	7594.0
RPL7	-5186.0	8598.0
RPL8	3526.0	820.0
RPLP2	3550.0	3555.0
RPS13	7174.0	315.0
RPS14	4070.0	4443.0
RPS15	7253.0	6174.0
RPS16	6244.0	1119.0
RPS17	5667.0	7685.0
RPS18	4253.0	-526.0
RPS19	6565.0	-1215.0
RPS2	7322.0	4216.0
RPS21	7111.0	-6494.0
RPS25	4261.0	8455.0
RPS27A	-133.0	-1807.0
RPS28	7208.0	-396.0
RPS3	2340.0	4381.0
RPS3A	-3115.0	8824.0
RPS4X	2522.0	7391.0
RPS5	3848.0	7515.0
RPS6	-1700.0	8603.0
RPS8	3874.0	7646.0
RPS9	-1719.0	-2555.0
UBA52	7488.0	-4269.0

---

---

L13a-mediated translational silencing of Ceruloplasmin expression

L13a-mediated translational silencing of Ceruloplasmin expression

metric	value
setSize	77
pMANOVA	7.06e-10
p.adjustMANOVA	3.66e-08
s.dist	0.386
s.diabetes	0.182
s.mitoG	0.34
p.diabetes	0.00586
p.mitoG	2.5e-07

Top 20 genes

Gene	diabetes	mitoG
RPL35	5949.0	8834.0
FAU	6809.0	7710.0
RPS15	7253.0	6174.0
RPS17	5667.0	7685.0
RPS25	4261.0	8455.0
RPL28	6714.0	4753.0
RPL26	3650.0	8722.0
RPL38	5601.0	5675.0
RPL19	4654.0	6782.0
RPS2	7322.0	4216.0
RPS8	3874.0	7646.0
RPS5	3848.0	7515.0
EIF3K	4728.0	6062.0
RPL32	2989.0	8728.0
EIF3L	5174.0	4824.0
EIF3C	4964.5	4995.5
RPL4	2582.0	8471.0
RPS4X	2522.0	7391.0
RPS14	4070.0	4443.0
RPL30	4372.0	3664.0

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
EIF2S1	-4830.0	8741.0
EIF2S2	-3307.0	8799.0
EIF2S3	-2819.5	4900.5
EIF3A	-4951.0	8381.0
EIF3B	-286.0	3875.0
EIF3C	4964.5	4995.5
EIF3D	511.0	8172.0
EIF3E	-4677.0	8580.0
EIF3F	2793.0	1790.0
EIF3G	836.0	1475.0
EIF3H	-4343.0	8629.0
EIF3I	5694.0	2343.0
EIF3J	-4890.0	8838.0
EIF3K	4728.0	6062.0
EIF3L	5174.0	4824.0
EIF3M	-2954.0	7258.0
EIF4A1	5335.0	61.0
EIF4A2	-6848.0	-699.0
EIF4B	-4266.0	-945.0
EIF4E	-4500.0	8429.0
EIF4G1	-5996.0	5731.0
EIF4H	5370.0	-98.0
FAU	6809.0	7710.0
PABPC1	-949.0	6861.0
RPL11	5748.0	1403.0
RPL12	6107.0	-5604.0
RPL13	5686.0	-3760.0
RPL14	5110.0	-1875.0
RPL18	2523.0	-625.0
RPL18A	4545.0	-3218.0
RPL19	4654.0	6782.0
RPL21	-1686.0	8463.0
RPL22	2365.0	459.0
RPL22L1	-5123.0	-6294.0
RPL23	-205.0	4253.0
RPL24	-409.0	6813.0
RPL26	3650.0	8722.0
RPL28	6714.0	4753.0
RPL29	2613.0	4628.0
RPL3	5378.0	1155.0
RPL30	4372.0	3664.0
RPL31	6732.0	-1507.0
RPL32	2989.0	8728.0
RPL34	661.0	7140.0
RPL35	5949.0	8834.0
RPL35A	-1509.0	6565.0
RPL36	7543.0	-2424.0
RPL36A	-5983.0	4837.0
RPL36AL	1793.0	-2074.0
RPL37	2109.0	-667.0
RPL38	5601.0	5675.0
RPL3L	-5986.0	4937.0
RPL4	2582.0	8471.0
RPL6	572.0	7594.0
RPL7	-5186.0	8598.0
RPL8	3526.0	820.0
RPLP2	3550.0	3555.0
RPS13	7174.0	315.0
RPS14	4070.0	4443.0
RPS15	7253.0	6174.0
RPS16	6244.0	1119.0
RPS17	5667.0	7685.0
RPS18	4253.0	-526.0
RPS19	6565.0	-1215.0
RPS2	7322.0	4216.0
RPS21	7111.0	-6494.0
RPS25	4261.0	8455.0
RPS27A	-133.0	-1807.0
RPS28	7208.0	-396.0
RPS3	2340.0	4381.0
RPS3A	-3115.0	8824.0
RPS4X	2522.0	7391.0
RPS5	3848.0	7515.0
RPS6	-1700.0	8603.0
RPS8	3874.0	7646.0
RPS9	-1719.0	-2555.0
UBA52	7488.0	-4269.0

---

---

Signaling by Interleukins

Signaling by Interleukins

metric	value
setSize	381
pMANOVA	7.8e-10
p.adjustMANOVA	3.9e-08
s.dist	0.205
s.diabetes	-0.0769
s.mitoG	0.19
p.diabetes	0.0103
p.mitoG	2.09e-10

Top 20 genes

Gene	diabetes	mitoG
HSP90AA1	-7286	8742
HSP90B1	-7279	8368
HSPA8	-7307	8180
PSMC6	-6851	8666
UBB	-7104	8341
CANX	-6936	8532
CAPZA1	-6942	8474
HMOX1	-7076	8232
PSME4	-6830	8511
SKP1	-6803	8394
IL13RA1	-7265	7820
PSMD1	-6497	8619
ITGB1	-6241	8758
JAK1	-6481	8390
PSMD12	-6149	8628
PSMD7	-6943	7625
PSMA1	-6705	7838
TAB2	-7040	7307
UBC	-6013	8514
PSMC4	-6423	7920

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
AGER	5844.0	-3308.0
AIP	-549.0	3479.0
AKT1	4859.0	7244.0
ALOX5	5079.0	-1468.0
ANXA1	7055.0	8221.0
ANXA2	-337.0	8406.0
APP	-5115.0	6758.0
ARF1	-5273.0	7470.0
ATF1	-4649.0	7196.0
ATF2	-4162.0	7780.0
BATF	574.0	313.0
BCL2	-1449.0	-2113.0
BCL2L1	1254.0	3623.0
BCL6	-4525.0	36.0
BIRC5	-3018.0	-2773.0
BLNK	6748.0	-965.0
BOLA2	5917.5	-478.5
BRWD1	3941.0	-3907.0
BTRC	3218.0	-5334.0
CANX	-6936.0	8532.0
CAPZA1	-6942.0	8474.0
CASP1	-1051.0	1558.0
CASP3	4881.0	3606.0
CBL	-6462.0	4306.0
CCL11	3017.0	670.0
CCL19	1486.0	-2403.0
CCL2	-1079.0	3167.0
CCL22	-3491.0	4025.0
CCL4	129.5	1818.5
CCL5	-3367.0	3393.0
CCND1	7933.0	-1628.0
CCR1	-3507.0	4981.0
CCR2	-6442.0	5692.0
CCR5	-1106.0	281.0
CD36	-7328.0	6006.0
CD4	409.0	5008.0
CD80	-3453.0	3286.0
CD86	-2679.0	5554.0
CDC42	-5961.0	8129.0
CDKN1A	7594.0	6372.0
CEBPD	3288.0	6984.0
CFL1	-1720.0	8321.0
CHUK	-3701.0	8556.0
CISH	-419.0	-2121.0
CLCF1	6318.0	-5706.0
CNN2	-2669.0	6553.0
CNTF	3748.0	3077.0
CNTFR	7636.0	-2686.0
COL1A2	416.0	5053.0
CREB1	-6809.0	5166.0
CRK	-3124.0	6926.0
CRKL	-4195.0	3246.0
CRLF1	5990.0	141.0
CRLF2	4692.0	-3614.0
CSF1	-2451.0	7450.0
CSF1R	-6805.0	2322.0
CSF2RA	-2892.0	-5044.0
CSF2RB	-5554.0	-817.0
CSF3R	-5607.0	5881.0
CTF1	601.0	-5358.0
CUL1	-2997.0	6875.0
CXCL10	-3846.0	6517.0
DUSP4	-2461.0	-1440.0
DUSP6	-5078.0	6412.0
DUSP7	7818.0	-3862.0
EBI3	3333.0	2001.0
ELK1	3201.0	-1060.0
F13A1	3019.0	4962.0
FASLG	834.0	4880.0
FBXW11	-3788.0	3125.0
FCER2	-3304.0	-718.0
FGF2	792.0	3696.0
FN1	7489.0	8379.0
FOS	827.0	3751.0
FOXO1	6562.0	90.0
FOXO3	7446.0	393.0
FSCN1	6020.0	3898.0
FYN	-2200.0	6221.0
GAB2	-717.0	7438.0
GATA3	7885.0	-1653.0
GRB2	3285.0	1922.0
GSTO1	8023.0	4922.0
H3C15	7988.0	2080.0
HAVCR2	-6021.0	6627.0
HCK	-3484.0	-1326.0
HGF	-6226.0	7929.0
HIF1A	7374.0	8562.0
HMGB1	2876.0	8283.0
HMOX1	-7076.0	8232.0
HNRNPA2B1	-2132.0	-151.0
HNRNPDL	8075.0	2325.0
HNRNPF	-4812.0	5595.0
HSP90AA1	-7286.0	8742.0
HSP90B1	-7279.0	8368.0
HSPA8	-7307.0	8180.0
HSPA9	-566.0	8181.0
ICAM1	7342.0	7752.0
IFNLR1	5476.0	1139.0
IKBKB	-1785.0	-5829.0
IKBKG	3700.0	-677.0
IL10RA	-6326.0	3465.0
IL10RB	-4532.0	-4965.0
IL11	-3409.0	1307.0
IL11RA	-5781.5	-1048.5
IL12RB1	4540.0	-5099.0
IL12RB2	28.0	-159.0
IL13RA1	-7265.0	7820.0
IL15	-4138.0	-2350.0
IL15RA	4967.0	-4955.0
IL16	-238.0	5474.0
IL17C	-1887.0	-3210.0
IL17F	243.0	-3130.0
IL17RA	-520.0	-3946.0
IL17RB	6676.0	-3477.0
IL17RC	6671.0	-6327.0
IL17RE	6664.0	4868.0
IL18	4167.0	-3592.0
IL18BP	5260.0	-3368.0
IL18R1	1538.0	151.0
IL18RAP	-2806.0	2792.0
IL1A	-1142.0	1688.0
IL1B	-6242.0	3978.0
IL1R1	3443.0	7288.0
IL1R2	-2817.0	6793.0
IL1RAP	1964.0	5164.0
IL1RAPL1	2419.0	-1284.0
IL1RL1	-1839.0	1060.0
IL1RL2	6863.0	1080.0
IL20RB	6541.0	-1964.0
IL21R	-2522.0	-4656.0
IL22RA1	-4036.0	-1035.0
IL23A	-2852.0	2958.0
IL23R	1187.0	2344.0
IL27RA	-2587.0	1948.0
IL2RA	62.0	288.0
IL2RB	-4367.0	-223.0
IL2RG	-4350.5	-961.5
IL31RA	2141.0	-1614.0
IL33	7328.0	7911.0
IL34	-7341.0	1594.0
IL36G	-2911.0	-6370.0
IL36RN	-1984.0	3989.0
IL4	4157.0	-5043.0
IL4R	647.0	5708.0
IL5RA	-3525.0	-463.0
IL6R	-730.0	6215.0
IL6ST	-6703.0	6610.0
IL7	1813.0	-1239.0
IL7R	-5696.0	8026.0
IL9R	-50.0	-4403.0
INPP5D	-1230.0	5535.0
INPPL1	-1829.0	-4396.0
IRAK1	-3742.0	4800.0
IRAK2	-879.0	-1594.0
IRAK3	4675.0	4623.0
IRAK4	2339.0	4636.0
IRF4	-1439.0	-700.0
IRS1	7064.0	-5549.0
IRS2	-582.0	3045.0
ITGAM	3292.0	5515.0
ITGAX	-5859.0	2296.0
ITGB1	-6241.0	8758.0
ITGB2	-5238.0	412.0
JAK1	-6481.0	8390.0
JAK2	-2268.0	5565.0
JAK3	7556.0	-6301.0
JUN	581.0	5314.0
JUNB	4544.0	2430.0
LAMA5	8212.0	-6404.0
LBP	4550.0	7403.0
LCK	-2194.0	5687.0
LCN2	5811.0	8293.0
LCP1	-6656.0	4745.0
LIF	352.0	2557.0
LIFR	4755.0	4346.0
LMNB1	6899.0	-4624.0
LYN	-4685.0	8216.0
MAOA	3741.0	-492.0
MAP2K1	7852.0	3274.0
MAP2K3	3494.0	-249.0
MAP2K4	2621.0	5572.0
MAP2K6	5640.0	-4115.0
MAP2K7	3505.0	-3383.0
MAP3K3	729.0	6115.0
MAP3K7	1594.0	7480.0
MAP3K8	656.0	2671.0
MAPK1	-3928.0	6920.0
MAPK10	-2089.0	-137.0
MAPK11	4349.0	2889.0
MAPK14	-6337.0	-1012.0
MAPK3	5390.0	5167.0
MAPK7	4710.0	-703.0
MAPK8	-3252.0	1695.0
MAPK9	2849.0	6624.0
MAPKAPK2	-2527.0	4587.0
MAPKAPK3	7267.0	-4297.0
MCL1	6260.0	-1020.0
MEF2A	-2071.0	7495.0
MEF2C	-1905.0	8451.0
MIF	8230.0	5317.0
MMP2	1375.0	7816.0
MMP3	-598.0	1929.0
MMP9	-5717.0	1502.0
MSN	-1294.0	5246.0
MTAP	-2386.0	7629.0
MUC1	7970.0	3179.0
MYC	1892.0	3123.0
MYD88	-5933.0	3612.0
NANOG	-2036.5	-2968.5
NDN	894.0	5072.0
NFKB1	5449.0	4035.0
NFKB2	2120.0	-4751.0
NFKBIA	1631.0	4830.0
NFKBIB	3850.0	467.0
NKIRAS1	-5446.0	5927.0
NKIRAS2	7425.0	286.0
NOD1	5283.0	4068.0
NOD2	-6286.0	2681.0
NOS2	-1104.0	4079.0
OPRD1	-1261.0	-2986.0
OPRM1	-459.0	-2620.0
OSMR	5259.0	8374.0
P4HB	-6743.0	5398.0
PAK2	-4906.0	6708.0
PDCD4	8018.0	3871.0
PELI1	2295.0	5683.0
PELI2	4968.0	-157.0
PELI3	7915.0	-6062.0
PIK3CA	-6347.0	2923.0
PIK3CB	-1756.0	1880.0
PIK3CD	-1968.0	1889.0
PIK3R1	-839.0	8363.0
PIK3R2	1669.5	-3969.5
PIK3R3	3779.5	8820.5
PIM1	-3615.0	5315.0
PITPNA	-912.0	8721.0
POMC	3685.0	-2222.0
POU2F1	6232.0	5561.0
PPIA	4868.0	-469.0
PPP2CA	-5725.0	8237.0
PPP2CB	5588.0	159.0
PPP2R1A	6355.0	3115.0
PPP2R1B	-6463.0	4855.0
PPP2R5D	2088.0	5911.0
PRKACA	-530.0	15.0
PSMA1	-6705.0	7838.0
PSMA2	-5464.5	6058.5
PSMA3	-3145.0	7801.0
PSMA4	-6074.0	4688.0
PSMA5	-6660.0	4497.0
PSMA6	-1954.0	8445.0
PSMA7	1612.0	7052.0
PSMA8	649.0	-4004.0
PSMB1	-5281.0	5936.0
PSMB10	3752.0	-908.0
PSMB11	1977.0	-5501.0
PSMB2	1472.0	-4144.0
PSMB3	-3388.0	5539.0
PSMB4	-4941.0	-5852.0
PSMB5	-1638.0	-2409.0
PSMB6	1806.0	-1845.0
PSMB7	-4628.0	-657.0
PSMB8	1080.0	-3793.0
PSMB9	5987.0	-4708.0
PSMC1	-1312.0	4327.0
PSMC2	-6765.0	4648.0
PSMC3	-4285.0	3386.0
PSMC4	-6423.0	7920.0
PSMC5	-4831.0	1120.0
PSMC6	-6851.0	8666.0
PSMD1	-6497.0	8619.0
PSMD10	-1613.0	2576.0
PSMD11	-6873.0	5201.0
PSMD12	-6149.0	8628.0
PSMD13	1898.0	5044.0
PSMD14	-6080.0	8262.0
PSMD2	-6702.0	-3836.0
PSMD3	-2532.0	-3242.0
PSMD4	-5648.0	4994.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
PSMD7	-6943.0	7625.0
PSMD8	1978.0	7546.0
PSMD9	7707.5	-894.5
PSME1	2907.0	5905.0
PSME2	1270.0	-4595.0
PSME3	752.0	7366.0
PSME4	-6830.0	8511.0
PSMF1	5087.0	4771.0
PTAFR	-5062.0	6031.0
PTGS2	-2970.0	5783.0
PTK2B	-5352.0	-3230.0
PTPN11	-3946.0	6142.0
PTPN12	-2782.0	8454.0
PTPN13	-3702.0	-4340.0
PTPN14	5809.0	5132.0
PTPN18	5824.0	-2434.0
PTPN2	-3709.0	8030.0
PTPN23	3670.0	-5769.0
PTPN4	-2725.0	7586.0
PTPN5	-1513.0	-1213.0
PTPN6	-1098.0	2140.0
PTPN7	-1757.0	-3829.0
PTPN9	2971.0	3715.0
PTPRZ1	3101.0	1373.0
RAG2	-807.0	3988.0
RALA	-5149.0	6748.0
RAP1B	942.0	8759.0
RAPGEF1	3892.0	3396.0
RBX1	-391.0	3201.0
RELA	2579.0	-2368.0
RHOU	-961.0	5238.0
RIPK2	5953.0	6306.0
RORA	-3317.0	3869.0
RORC	4429.0	-1569.0
RPS27A	-133.0	-1807.0
RPS6KA1	7703.0	4452.0
RPS6KA2	7237.0	-2956.0
RPS6KA3	-6111.0	8270.0
RPS6KA5	2516.0	-3206.0
S100B	1781.0	-995.0
S1PR1	4311.0	7637.0
SDC1	6076.0	6227.0
SHC1	568.0	1962.0
SIGIRR	-826.0	-4627.0
SKP1	-6803.0	8394.0
SMAD3	-1639.0	-2520.0
SMARCA4	-2170.0	4097.0
SNRPA1	4691.0	-2581.0
SOCS1	-253.0	-5520.0
SOCS2	4529.0	3280.0
SOCS3	4231.0	7185.0
SOCS5	1959.0	-4114.0
SOD1	-7054.0	2583.0
SOD2	-1635.0	4013.0
SOS1	-6566.0	7698.0
SOS2	-4341.0	7073.0
SQSTM1	-5419.0	2021.0
STAT1	-3464.0	-4440.0
STAT2	4437.0	-4922.0
STAT3	8126.0	4982.0
STAT4	-3850.0	4337.0
STAT5A	2714.0	-3795.0
STAT5B	4664.0	-4634.0
STAT6	-6946.0	2330.0
STX1A	2774.0	-2559.0
STX3	7132.0	3726.0
STX4	-3184.0	-4491.0
STXBP2	6798.0	725.0
SYK	-6921.0	4480.0
TAB1	7839.0	-5339.0
TAB2	-7040.0	7307.0
TAB3	3966.0	5424.0
TALDO1	-5386.0	449.0
TBK1	-5003.0	4897.0
TCP1	-6476.0	7694.0
TEC	-5516.0	6783.0
TGFB1	-1851.0	6152.0
TIMP1	-2454.0	3444.0
TNF	-2778.0	4883.0
TNFRSF1A	6733.0	6743.0
TNFRSF1B	-5427.0	939.0
TNIP2	7153.0	-6672.0
TOLLIP	5721.0	3964.0
TP53	2557.0	-3561.0
TRAF6	1082.0	6626.0
TWIST1	2436.0	2787.0
TXLNA	1173.0	-4792.0
TYK2	3318.0	-6265.0
UBA52	7488.0	-4269.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
VAMP2	8086.5	-3275.5
VAV1	-4395.0	5076.0
VCAM1	-4983.0	4280.0
VEGFA	-4619.0	-5156.0
VIM	5500.0	7940.0
VRK3	-4442.0	-4059.0
YES1	-120.0	7265.0
YWHAZ	-5614.0	8512.0
ZEB1	1347.0	8478.0

---

---

Elastic fibre formation

Elastic fibre formation

metric	value
setSize	37
pMANOVA	1.43e-09
p.adjustMANOVA	6.91e-08
s.dist	0.549
s.diabetes	0.234
s.mitoG	0.497
p.diabetes	0.0137
p.mitoG	1.7e-07

Top 20 genes

Gene	diabetes	mitoG
LOX	7282.0	7922.0
LOXL1	6829.0	8361.0
FBN1	6578.0	8391.0
BMP4	6672.0	7143.0
EFEMP1	6611.0	6380.0
ITGA5	5929.0	6964.0
LOXL2	5024.0	8008.0
FBLN2	4810.0	7504.0
FBLN5	4332.0	8272.0
BMP2	4300.0	7938.0
LOXL3	4869.0	6408.0
TGFB2	4490.0	6652.0
ITGAV	8155.0	2693.0
EFEMP2	2292.0	7425.0
MFAP3	2866.0	4624.0
ITGB5	7359.0	1316.0
ITGB3	1530.5	4298.5
MFAP2	6000.0	930.0
MFAP5	479.0	5300.0
LTBP2	415.0	4760.0

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
BMP2	4300.0	7938.0
BMP4	6672.0	7143.0
BMP7	8109.0	-1080.0
EFEMP1	6611.0	6380.0
EFEMP2	2292.0	7425.0
ELN	3735.0	-4141.0
FBLN1	1746.0	16.0
FBLN2	4810.0	7504.0
FBLN5	4332.0	8272.0
FBN1	6578.0	8391.0
FBN2	-2413.0	6151.0
FURIN	3696.0	-3590.0
ITGA5	5929.0	6964.0
ITGA8	-802.0	4862.0
ITGAV	8155.0	2693.0
ITGB1	-6241.0	8758.0
ITGB3	1530.5	4298.5
ITGB5	7359.0	1316.0
ITGB6	-7094.0	613.0
ITGB8	-1078.0	2920.0
LOX	7282.0	7922.0
LOXL1	6829.0	8361.0
LOXL2	5024.0	8008.0
LOXL3	4869.0	6408.0
LOXL4	-1571.0	8483.0
LTBP1	-5412.0	7176.0
LTBP2	415.0	4760.0
LTBP3	8038.0	-540.0
LTBP4	-6699.0	5054.0
MFAP1	-1345.0	8624.0
MFAP2	6000.0	930.0
MFAP3	2866.0	4624.0
MFAP4	-1577.0	2378.0
MFAP5	479.0	5300.0
TGFB1	-1851.0	6152.0
TGFB2	4490.0	6652.0
TGFB3	-1546.0	8322.0

---

---

Regulation of actin dynamics for phagocytic cup formation

Regulation of actin dynamics for phagocytic cup formation

metric	value
setSize	76
pMANOVA	1.57e-09
p.adjustMANOVA	7.15e-08
s.dist	0.434
s.diabetes	-0.0974
s.mitoG	0.422
p.diabetes	0.143
p.mitoG	1.93e-10

Top 20 genes

Gene	diabetes	mitoG
IGHV1-69	-7353.5	8845.5
IGKV4-1	-7301.0	8840.0
HSP90AA1	-7286.0	8742.0
IGKV5-2	-5895.0	8671.0
NCKAP1	-5953.0	8521.0
ARPC3	-5747.0	8757.0
CDC42	-5961.0	8129.0
FCGR2A	-7297.0	5966.0
HSP90AB1	-7306.0	5626.0
ARPC2	-4512.0	8767.0
NCK1	-4610.0	8438.0
ABI1	-4630.0	8305.0
ACTR2	-5189.0	7356.0
FCGR3A	-5407.5	6212.5
ACTB	-4152.0	7953.0
WASL	-3989.0	7855.0
SYK	-6921.0	4480.0
ACTR3	-3716.0	8206.0
WIPF1	-3718.0	7829.0
BTK	-5279.0	5486.0

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
ABI1	-4630.0	8305.0
ABI2	4154.0	8369.0
ABL1	5557.0	-3567.0
ACTB	-4152.0	7953.0
ACTG1	-1502.0	1482.0
ACTR2	-5189.0	7356.0
ACTR3	-3716.0	8206.0
ARPC1A	-1009.0	-3070.0
ARPC1B	7126.0	2266.0
ARPC2	-4512.0	8767.0
ARPC3	-5747.0	8757.0
ARPC4	3077.0	1525.0
ARPC5	920.0	7514.0
BAIAP2	7911.0	534.0
BRK1	751.0	1659.0
BTK	-5279.0	5486.0
CD247	1213.0	-5666.0
CD3G	-1784.0	-3919.0
CDC42	-5961.0	8129.0
CFL1	-1720.0	8321.0
CRK	-3124.0	6926.0
CYFIP1	3175.0	7476.0
CYFIP2	7791.0	-143.0
DOCK1	2243.0	382.0
ELMO1	-4833.0	4917.0
ELMO2	6218.0	-536.0
FCGR1A	-5675.5	4265.5
FCGR2A	-7297.0	5966.0
FCGR3A	-5407.5	6212.5
GRB2	3285.0	1922.0
HSP90AA1	-7286.0	8742.0
HSP90AB1	-7306.0	5626.0
IGHV1-69	-7353.5	8845.5
IGHV2-5	4395.0	4965.0
IGHV2-70	4395.0	4965.0
IGHV7-81	517.5	7570.5
IGKC	-2925.0	7318.0
IGKV1-12	2052.5	4944.5
IGKV1-17	2052.5	4944.5
IGKV1-39	2052.5	4944.5
IGKV1D-12	2052.5	4944.5
IGKV1D-39	2052.5	4944.5
IGKV2-30	101.5	8396.5
IGKV2D-30	101.5	8396.5
IGKV4-1	-7301.0	8840.0
IGKV5-2	-5895.0	8671.0
IGLV4-60	-3537.5	3617.5
IGLV4-69	-3537.5	3617.5
LIMK1	3519.0	2264.0
MAPK1	-3928.0	6920.0
MAPK3	5390.0	5167.0
MYH9	7189.0	7115.0
MYO10	4745.0	-1478.0
MYO1C	7502.0	5436.0
MYO5A	-7077.0	3216.0
MYO9B	1982.0	-237.0
NCK1	-4610.0	8438.0
NCKAP1	-5953.0	8521.0
NCKAP1L	-1592.0	4630.0
NCKIPSD	7238.0	-4983.0
NF2	215.0	5920.0
PAK1	-886.0	5458.0
PTK2	2264.0	6997.0
RAC1	-1258.0	4008.0
SYK	-6921.0	4480.0
VAV1	-4395.0	5076.0
VAV2	2432.0	-843.0
VAV3	6942.0	5027.0
WAS	-11.0	299.0
WASF1	-5233.0	-3651.0
WASF2	4804.0	1618.0
WASF3	4712.0	680.0
WASL	-3989.0	7855.0
WIPF1	-3718.0	7829.0
WIPF2	4034.0	-1247.0
WIPF3	7332.0	3435.0

---

---

Signaling by ROBO receptors

Signaling by ROBO receptors

metric	value
setSize	177
pMANOVA	1.58e-09
p.adjustMANOVA	7.15e-08
s.dist	0.281
s.diabetes	-0.0472
s.mitoG	0.277
p.diabetes	0.28
p.mitoG	2.01e-10

Top 20 genes

Gene	diabetes	mitoG
PSMC6	-6851	8666
UBB	-7104	8341
PSME4	-6830	8511
PSMD1	-6497	8619
UPF2	-6949	7960
GSPT1	-6653	8055
PSMD12	-6149	8628
CUL2	-6236	8506
PSMD7	-6943	7625
PSMA1	-6705	7838
UBC	-6013	8514
PSMC4	-6423	7920
SOS1	-6566	7698
PSMD14	-6080	8262
USP33	-7002	7120
CDC42	-5961	8129
RPL7	-5186	8598
PSMD5	-6156	7150
RHOA	-5203	7671
PSMD6	-6385	6157

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
ABL1	5557.0	-3567.0
ABL2	-4140.0	5490.0
AKAP5	6430.0	224.0
ARHGAP39	-3999.0	-4879.0
CAP1	-1701.0	6877.0
CAP2	-919.0	1714.0
CASC3	-1205.0	-683.0
CDC42	-5961.0	8129.0
CLASP1	-1488.0	3748.0
CLASP2	7216.0	4174.0
COL4A5	-1115.0	-5623.0
CUL2	-6236.0	8506.0
CXCL12	8169.0	7982.0
CXCR4	4516.0	7547.0
DAG1	6646.0	3480.0
EIF4A3	2375.0	2229.0
EIF4G1	-5996.0	5731.0
ELOB	6643.0	3269.0
ELOC	-3325.0	7837.0
ENAH	5226.0	20.0
ETF1	-3268.0	8174.0
EVL	-186.0	264.0
FAU	6809.0	7710.0
FLRT3	-4355.0	5017.0
GPC1	7890.0	581.0
GSPT1	-6653.0	8055.0
GSPT2	-1500.0	-264.0
HOXA2	1984.0	-3355.0
LDB1	7924.0	2101.0
LHX4	-3273.0	943.0
LHX9	192.0	3071.0
MAGOH	-2387.0	7841.0
MAGOHB	1654.0	1040.0
MSI1	7619.0	-2384.0
MYO9B	1982.0	-237.0
NCBP1	-6452.0	5580.0
NCBP2	-6814.0	136.0
NCK1	-4610.0	8438.0
NCK2	-5808.0	458.0
NELL2	979.0	-3113.0
NRP1	-6603.0	5497.0
NTN1	-7314.0	-3261.0
PABPC1	-949.0	6861.0
PAK1	-886.0	5458.0
PAK2	-4906.0	6708.0
PAK3	2878.0	1881.0
PAK4	-1749.0	-1353.0
PAK6	6221.0	5140.0
PFN1	-3462.0	-4129.0
PFN2	701.0	4388.0
PPP3CB	-1150.0	4729.0
PRKACA	-530.0	15.0
PRKACB	569.0	661.0
PRKAR2A	5319.0	7462.0
PRKCA	-6271.0	3380.0
PSMA1	-6705.0	7838.0
PSMA2	-5464.5	6058.5
PSMA3	-3145.0	7801.0
PSMA4	-6074.0	4688.0
PSMA5	-6660.0	4497.0
PSMA6	-1954.0	8445.0
PSMA7	1612.0	7052.0
PSMA8	649.0	-4004.0
PSMB1	-5281.0	5936.0
PSMB10	3752.0	-908.0
PSMB11	1977.0	-5501.0
PSMB2	1472.0	-4144.0
PSMB3	-3388.0	5539.0
PSMB4	-4941.0	-5852.0
PSMB5	-1638.0	-2409.0
PSMB6	1806.0	-1845.0
PSMB7	-4628.0	-657.0
PSMB8	1080.0	-3793.0
PSMB9	5987.0	-4708.0
PSMC1	-1312.0	4327.0
PSMC2	-6765.0	4648.0
PSMC3	-4285.0	3386.0
PSMC4	-6423.0	7920.0
PSMC5	-4831.0	1120.0
PSMC6	-6851.0	8666.0
PSMD1	-6497.0	8619.0
PSMD10	-1613.0	2576.0
PSMD11	-6873.0	5201.0
PSMD12	-6149.0	8628.0
PSMD13	1898.0	5044.0
PSMD14	-6080.0	8262.0
PSMD2	-6702.0	-3836.0
PSMD3	-2532.0	-3242.0
PSMD4	-5648.0	4994.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
PSMD7	-6943.0	7625.0
PSMD8	1978.0	7546.0
PSMD9	7707.5	-894.5
PSME1	2907.0	5905.0
PSME2	1270.0	-4595.0
PSME3	752.0	7366.0
PSME4	-6830.0	8511.0
PSMF1	5087.0	4771.0
RAC1	-1258.0	4008.0
RBM8A	-4975.0	7751.0
RBX1	-391.0	3201.0
RHOA	-5203.0	7671.0
RNPS1	5559.0	6960.0
ROBO1	3335.0	7441.0
ROBO2	4411.0	8685.0
ROBO3	-5418.0	-1877.0
RPL11	5748.0	1403.0
RPL12	6107.0	-5604.0
RPL13	5686.0	-3760.0
RPL14	5110.0	-1875.0
RPL18	2523.0	-625.0
RPL18A	4545.0	-3218.0
RPL19	4654.0	6782.0
RPL21	-1686.0	8463.0
RPL22	2365.0	459.0
RPL22L1	-5123.0	-6294.0
RPL23	-205.0	4253.0
RPL24	-409.0	6813.0
RPL26	3650.0	8722.0
RPL28	6714.0	4753.0
RPL29	2613.0	4628.0
RPL3	5378.0	1155.0
RPL30	4372.0	3664.0
RPL31	6732.0	-1507.0
RPL32	2989.0	8728.0
RPL34	661.0	7140.0
RPL35	5949.0	8834.0
RPL35A	-1509.0	6565.0
RPL36	7543.0	-2424.0
RPL36A	-5983.0	4837.0
RPL36AL	1793.0	-2074.0
RPL37	2109.0	-667.0
RPL38	5601.0	5675.0
RPL3L	-5986.0	4937.0
RPL4	2582.0	8471.0
RPL6	572.0	7594.0
RPL7	-5186.0	8598.0
RPL8	3526.0	820.0
RPLP2	3550.0	3555.0
RPS13	7174.0	315.0
RPS14	4070.0	4443.0
RPS15	7253.0	6174.0
RPS16	6244.0	1119.0
RPS17	5667.0	7685.0
RPS18	4253.0	-526.0
RPS19	6565.0	-1215.0
RPS2	7322.0	4216.0
RPS21	7111.0	-6494.0
RPS25	4261.0	8455.0
RPS27A	-133.0	-1807.0
RPS28	7208.0	-396.0
RPS3	2340.0	4381.0
RPS3A	-3115.0	8824.0
RPS4X	2522.0	7391.0
RPS5	3848.0	7515.0
RPS6	-1700.0	8603.0
RPS8	3874.0	7646.0
RPS9	-1719.0	-2555.0
SLIT1	1701.0	-4596.0
SLIT2	737.0	-1675.0
SLIT3	6674.0	8430.0
SOS1	-6566.0	7698.0
SOS2	-4341.0	7073.0
SRC	-2657.0	-1643.0
SRGAP1	3092.0	5935.0
SRGAP2	-1169.0	-688.0
SRGAP3	6392.0	4176.0
UBA52	7488.0	-4269.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
UPF2	-6949.0	7960.0
UPF3A	-1867.0	3076.0
UPF3B	3082.0	2946.0
USP33	-7002.0	7120.0
VASP	-2568.0	4503.0
ZSWIM8	6016.0	-3044.0

---

---

Cellular responses to external stimuli

Cellular responses to external stimuli

metric	value
setSize	470
pMANOVA	1.78e-09
p.adjustMANOVA	7.78e-08
s.dist	0.167
s.diabetes	0.00238
s.mitoG	0.167
p.diabetes	0.93
p.mitoG	6.23e-10

Top 20 genes

Gene	diabetes	mitoG
HIF1A	7374	8562
H1-4	7392	8249
CSRP1	7337	8301
EPAS1	6886	8502
MT2A	8239	7031
RB1	7982	7013
RPL35	5949	8834
FAU	6809	7710
H1-0	7817	6665
CDKN1A	7594	6372
MT1G	8262	5621
RPS15	7253	6174
MDM2	5569	7967
RPS17	5667	7685
STAT3	8126	4982
BAG4	7654	5147
HSPA2	7012	5387
ANAPC4	6315	5808
RPS25	4261	8455
FKBP5	6201	5807

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
AAAS	5561.0	-2261.0
ACD	5902.0	-6561.0
ACTR10	268.0	6666.0
ACTR1A	965.0	5035.0
AGO1	6080.0	-4094.0
AGO3	-1670.0	-1990.0
AGO4	2726.0	6474.0
AJUBA	-194.0	-1290.0
AKT1S1	3062.0	-5699.0
ANAPC1	-6298.0	2903.0
ANAPC10	-1783.0	4951.0
ANAPC15	4299.0	155.0
ANAPC16	2.0	1444.0
ANAPC2	-3336.0	-4659.0
ANAPC4	6315.0	5808.0
ANAPC5	6285.0	-1473.0
ANAPC7	5249.0	-3454.0
AQP8	-3980.0	1683.0
AR	2841.0	2349.0
ARNT	1247.0	2255.0
ASF1A	-4510.0	7034.0
ASNS	419.0	3160.0
ATF2	-4162.0	7780.0
ATF3	-845.0	6400.0
ATF4	-6143.0	7857.0
ATF5	342.0	3756.0
ATM	5701.0	-2536.0
ATOX1	8025.0	-3520.0
ATP6V0B	-1247.0	-3182.0
ATP6V0C	1078.0	-2076.0
ATP6V0D1	-3890.0	3817.0
ATP6V0D2	3320.0	5793.0
ATP6V0E1	1832.0	3873.0
ATP6V0E2	158.0	-4784.0
ATP6V1A	4631.0	5077.0
ATP6V1B1	7324.0	-1200.0
ATP6V1B2	2487.0	2135.0
ATP6V1C1	-3690.0	-528.0
ATP6V1C2	3469.0	5006.0
ATP6V1D	-3259.0	8108.0
ATP6V1E1	-704.0	8548.0
ATP6V1F	5567.0	1498.0
ATP6V1G1	7327.0	4738.0
ATP6V1G2	-2452.0	921.0
ATP6V1G3	-2690.0	4036.0
ATP6V1H	-1095.0	8501.0
ATP7A	-3222.0	7692.0
ATR	234.0	5001.0
BAG1	2254.0	6318.0
BAG2	6922.0	3368.0
BAG3	-6860.0	6695.0
BAG4	7654.0	5147.0
BAG5	-2637.0	8168.0
BMI1	-4453.5	8309.5
BMT2	-4495.0	6954.0
C12orf66	5492.0	-1861.0
CA9	-2361.0	-2782.0
CABIN1	5467.0	-5948.0
CAMK2A	-2272.0	4664.0
CAMK2B	2551.0	5253.0
CAMK2G	5581.0	-3540.0
CAPZA1	-6942.0	8474.0
CAPZA2	-1687.0	8135.0
CAPZB	-2513.0	7203.0
CAT	-602.0	4907.0
CBX2	1808.0	-1479.0
CBX4	3352.0	-2144.0
CBX6	3215.0	-5159.0
CBX8	-2773.0	176.0
CCAR2	6598.0	-4714.0
CCNA2	4669.0	307.0
CCNE1	5096.0	360.0
CCNE2	2080.0	3324.0
CCS	6336.0	-6627.0
CDC16	6701.0	3924.0
CDC23	1748.0	710.0
CDC26	-3331.0	1610.0
CDC27	-4452.0	8433.0
CDK2	6186.0	-4240.0
CDK4	3355.0	-1971.0
CDK6	-5570.0	908.0
CDKN1A	7594.0	6372.0
CDKN1B	541.0	3790.0
CDKN2B	4291.0	-154.0
CDKN2C	6608.0	-3067.0
CDKN2D	6687.0	-4576.0
CEBPB	7403.0	754.0
CEBPG	-3135.0	6916.0
CHAC1	-5498.0	4031.0
CITED2	-1285.0	2778.0
COL4A6	-3205.0	1099.0
CREBBP	-6181.0	3954.0
CRYAB	6594.0	3169.0
CSRP1	7337.0	8301.0
CUL2	-6236.0	8506.0
CYBA	-4719.0	-4200.0
CYBB	-5520.0	5307.0
DCTN1	7218.0	-3098.0
DCTN2	2623.0	-2017.0
DCTN3	-715.0	689.0
DCTN4	-4133.0	7527.0
DCTN5	-4033.0	5094.0
DCTN6	4374.0	7565.0
DDIT3	-2070.0	-609.0
DEDD2	242.0	-4343.0
DEPDC5	7514.5	-6056.5
DNAJA1	-7303.0	6518.0
DNAJA2	-3327.0	8515.0
DNAJA4	-7004.0	6662.0
DNAJB1	-7114.0	1852.0
DNAJB6	-6088.0	7159.0
DNAJC2	-5076.0	7232.0
DNAJC7	-426.0	397.0
DYNC1H1	4822.0	2594.0
DYNC1I1	3045.0	-5230.0
DYNC1I2	-251.0	7398.0
DYNC1LI1	2249.0	7292.0
DYNC1LI2	-1436.0	1861.0
DYNLL1	-6952.0	7645.0
DYNLL2	4932.0	-5028.0
E2F1	4935.0	-488.0
E2F2	-2674.0	6447.0
E2F3	-3234.0	5297.0
EED	-1977.0	6430.0
EGLN1	-4261.5	-1804.5
EGLN2	1424.0	-6238.0
EGLN3	7904.0	4308.0
EHMT1	4203.0	1615.0
EHMT2	-610.0	-4085.0
EIF2AK1	-3590.0	6471.0
EIF2AK4	6877.0	-576.0
EIF2S1	-4830.0	8741.0
EIF2S2	-3307.0	8799.0
EIF2S3	-2819.5	4900.5
ELOB	6643.0	3269.0
ELOC	-3325.0	7837.0
EP300	-2449.0	1336.0
EP400	-2629.0	-5737.0
EPAS1	6886.0	8502.0
EPO	-1520.0	-1660.0
ERF	8190.0	-6273.0
ERO1A	3390.0	4892.0
ETS1	-599.0	8648.0
ETS2	2507.0	8278.0
EZH2	13.0	1789.0
FAU	6809.0	7710.0
FKBP4	-7096.0	-111.0
FKBP5	6201.0	5807.0
FNIP1	624.0	5543.0
FNIP2	7643.0	-6483.0
FOS	827.0	3751.0
FZR1	3996.0	-5000.0
GCN1	4616.0	-6124.0
GPX1	-1077.0	736.0
GPX3	7210.0	955.0
GPX6	7582.0	1018.0
GPX7	1995.0	2462.0
GPX8	-3495.0	7792.0
GRB10	-6904.0	2705.0
GSK3B	-5423.0	7184.0
GSR	-2480.0	4329.0
GSTP1	1683.0	2544.0
H1-0	7817.0	6665.0
H1-1	4222.0	7277.0
H1-2	7795.0	4082.0
H1-3	3925.0	-879.0
H1-4	7392.0	8249.0
H1-5	-1450.0	1228.0
H2AC20	7413.0	2470.0
H2AJ	-5416.0	2537.0
H2AZ1	-980.0	4206.0
H2AZ2	3558.0	1431.0
H2BC11	3900.0	-3127.0
H2BC14	1703.0	1613.0
H2BC5	3445.0	-761.0
H3-3A	-1695.0	7826.0
H3C15	7988.0	2080.0
HDAC6	7878.0	1757.0
HIF1A	7374.0	8562.0
HIF1AN	1768.0	-4927.0
HIF3A	5098.0	-246.0
HIGD1A	359.0	-3963.0
HIKESHI	-5969.0	1619.0
HIRA	-6015.0	-99.0
HMGA1	7803.0	-1488.0
HSF1	-1770.0	-3977.0
HSP90AA1	-7286.0	8742.0
HSP90AB1	-7306.0	5626.0
HSPA12A	-4571.0	1589.0
HSPA12B	4183.0	-2830.0
HSPA13	-7108.0	8023.0
HSPA14	3648.0	-1181.0
HSPA1A	-7272.5	7293.5
HSPA1B	-7272.5	7293.5
HSPA1L	-3778.0	-133.0
HSPA2	7012.0	5387.0
HSPA4	-6676.0	8292.0
HSPA4L	-7193.0	8500.0
HSPA5	-7309.0	7589.0
HSPA8	-7307.0	8180.0
HSPA9	-566.0	8181.0
HSPB8	-1109.0	6214.0
HSPH1	-7334.0	5252.0
ID1	3953.0	-1529.0
IGFBP7	-655.0	-4154.0
IL1A	-1142.0	1688.0
IMPACT	-2890.0	3450.0
ITFG2	826.0	-4600.0
JUN	581.0	5314.0
KAT5	5775.0	2767.0
KDM6B	7513.0	-6408.0
KPTN	3882.0	-3219.0
LAMTOR1	-81.0	-630.0
LAMTOR2	-2847.0	1280.0
LAMTOR3	2323.0	4870.0
LAMTOR4	-361.0	-1888.0
LAMTOR5	4258.0	4393.0
LIMD1	86.0	-5162.0
LMNB1	6899.0	-4624.0
MAP2K3	3494.0	-249.0
MAP2K4	2621.0	5572.0
MAP2K6	5640.0	-4115.0
MAP2K7	3505.0	-3383.0
MAP3K5	-5240.0	4568.0
MAP4K4	3979.0	7914.0
MAPK1	-3928.0	6920.0
MAPK10	-2089.0	-137.0
MAPK11	4349.0	2889.0
MAPK14	-6337.0	-1012.0
MAPK3	5390.0	5167.0
MAPK7	4710.0	-703.0
MAPK8	-3252.0	1695.0
MAPK9	2849.0	6624.0
MAPKAPK2	-2527.0	4587.0
MAPKAPK3	7267.0	-4297.0
MAPKAPK5	1373.0	5493.0
MDM2	5569.0	7967.0
MDM4	-2223.0	-5305.0
MINK1	-4877.0	-2450.0
MIOS	3016.0	4108.0
MLST8	-977.0	-1211.0
MOV10	-1088.0	-5618.0
MRE11	-3060.0	3329.0
MRPL18	-4156.0	1438.0
MT1G	8262.0	5621.0
MT2A	8239.0	7031.0
MT3	-369.0	-3432.0
MTF1	-4371.0	-3922.0
MTOR	-4145.0	-2344.0
NBN	-5298.0	8349.0
NCF1	3710.0	-659.0
NCF2	-1972.0	-3232.0
NCF4	-5987.0	5579.0
NDC1	6665.0	-1084.0
NFKB1	5449.0	4035.0
NOX4	7658.0	2944.0
NPRL2	-3789.0	2965.0
NPRL3	3415.0	-4551.0
NR3C1	-2732.0	2240.0
NR3C2	7008.0	-3900.0
NUDT2	1738.0	2579.0
NUP107	3423.0	7169.0
NUP133	2759.0	-4113.0
NUP153	-4638.0	7763.0
NUP155	6347.0	2192.0
NUP160	-5230.0	1753.0
NUP188	3880.0	-4145.0
NUP205	855.0	6303.0
NUP210	8193.0	-4172.0
NUP214	7802.0	-5326.0
NUP35	-4374.0	-921.0
NUP37	3596.0	1004.0
NUP42	4998.0	-596.0
NUP43	-2270.0	3764.0
NUP50	-4961.0	641.0
NUP54	-3355.0	6010.0
NUP58	2230.0	7116.0
NUP62	4963.0	-4765.0
NUP85	1103.0	-4750.0
NUP88	4817.0	4002.0
NUP93	5331.0	6196.0
NUP98	-2590.0	5122.0
P4HB	-6743.0	5398.0
PGR	-4247.0	5891.0
PHC1	-3375.0	-2631.0
PHC2	4373.0	-2023.0
PHC3	-3667.0	-4511.0
POM121	3732.5	-6552.5
POM121C	3732.5	-6552.5
POT1	-1630.0	-4746.0
PPP1R15A	7471.0	4761.0
PRDX1	-6422.0	8698.0
PRDX2	4337.0	4730.0
PRDX3	5471.0	4673.0
PRDX5	-4102.0	2801.0
PRDX6	-3287.0	3877.0
PSMA1	-6705.0	7838.0
PSMA2	-5464.5	6058.5
PSMA3	-3145.0	7801.0
PSMA4	-6074.0	4688.0
PSMA5	-6660.0	4497.0
PSMA6	-1954.0	8445.0
PSMA7	1612.0	7052.0
PSMA8	649.0	-4004.0
PSMB1	-5281.0	5936.0
PSMB10	3752.0	-908.0
PSMB11	1977.0	-5501.0
PSMB2	1472.0	-4144.0
PSMB3	-3388.0	5539.0
PSMB4	-4941.0	-5852.0
PSMB5	-1638.0	-2409.0
PSMB6	1806.0	-1845.0
PSMB7	-4628.0	-657.0
PSMB8	1080.0	-3793.0
PSMB9	5987.0	-4708.0
PSMC1	-1312.0	4327.0
PSMC2	-6765.0	4648.0
PSMC3	-4285.0	3386.0
PSMC4	-6423.0	7920.0
PSMC5	-4831.0	1120.0
PSMC6	-6851.0	8666.0
PSMD1	-6497.0	8619.0
PSMD10	-1613.0	2576.0
PSMD11	-6873.0	5201.0
PSMD12	-6149.0	8628.0
PSMD13	1898.0	5044.0
PSMD14	-6080.0	8262.0
PSMD2	-6702.0	-3836.0
PSMD3	-2532.0	-3242.0
PSMD4	-5648.0	4994.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
PSMD7	-6943.0	7625.0
PSMD8	1978.0	7546.0
PSMD9	7707.5	-894.5
PSME1	2907.0	5905.0
PSME2	1270.0	-4595.0
PSME3	752.0	7366.0
PSME4	-6830.0	8511.0
PSMF1	5087.0	4771.0
PTGES3	-7067.0	8733.0
RAD50	6606.5	676.5
RAE1	3041.0	-1934.0
RANBP2	-4575.0	8132.0
RB1	7982.0	7013.0
RBBP4	-6148.0	5835.0
RBBP7	2154.0	6750.0
RBX1	-391.0	3201.0
RELA	2579.0	-2368.0
RHEB	-3280.0	-1691.0
RING1	2092.0	-5540.0
RLN1	2347.5	469.5
RNF2	-3811.0	8651.0
RPA1	4920.0	5750.0
RPA2	6082.0	4722.0
RPA3	3029.0	1440.0
RPL11	5748.0	1403.0
RPL12	6107.0	-5604.0
RPL13	5686.0	-3760.0
RPL14	5110.0	-1875.0
RPL18	2523.0	-625.0
RPL18A	4545.0	-3218.0
RPL19	4654.0	6782.0
RPL21	-1686.0	8463.0
RPL22	2365.0	459.0
RPL22L1	-5123.0	-6294.0
RPL23	-205.0	4253.0
RPL24	-409.0	6813.0
RPL26	3650.0	8722.0
RPL28	6714.0	4753.0
RPL29	2613.0	4628.0
RPL3	5378.0	1155.0
RPL30	4372.0	3664.0
RPL31	6732.0	-1507.0
RPL32	2989.0	8728.0
RPL34	661.0	7140.0
RPL35	5949.0	8834.0
RPL35A	-1509.0	6565.0
RPL36	7543.0	-2424.0
RPL36A	-5983.0	4837.0
RPL36AL	1793.0	-2074.0
RPL37	2109.0	-667.0
RPL38	5601.0	5675.0
RPL3L	-5986.0	4937.0
RPL4	2582.0	8471.0
RPL6	572.0	7594.0
RPL7	-5186.0	8598.0
RPL8	3526.0	820.0
RPLP2	3550.0	3555.0
RPS13	7174.0	315.0
RPS14	4070.0	4443.0
RPS15	7253.0	6174.0
RPS16	6244.0	1119.0
RPS17	5667.0	7685.0
RPS18	4253.0	-526.0
RPS19	6565.0	-1215.0
RPS19BP1	-6099.0	5732.0
RPS2	7322.0	4216.0
RPS21	7111.0	-6494.0
RPS25	4261.0	8455.0
RPS27A	-133.0	-1807.0
RPS28	7208.0	-396.0
RPS3	2340.0	4381.0
RPS3A	-3115.0	8824.0
RPS4X	2522.0	7391.0
RPS5	3848.0	7515.0
RPS6	-1700.0	8603.0
RPS6KA1	7703.0	4452.0
RPS6KA2	7237.0	-2956.0
RPS6KA3	-6111.0	8270.0
RPS8	3874.0	7646.0
RPS9	-1719.0	-2555.0
RPTOR	1708.0	-6268.0
RRAGA	-3310.0	5815.0
RRAGB	1312.0	-1809.0
RRAGC	-2715.0	5320.0
RRAGD	7798.0	3815.0
SCMH1	2113.0	-1086.0
SEC13	-1432.0	3604.0
SEH1L	2204.0	6910.0
SERPINH1	-7218.0	4296.0
SESN1	6129.0	5296.0
SESN2	-4377.0	1285.0
SH3BP4	7669.0	3702.0
SIRT1	165.0	6375.0
SLC38A9	-1355.0	-5207.0
SOD1	-7054.0	2583.0
SOD2	-1635.0	4013.0
SOD3	-1080.0	-2376.0
SP1	571.0	4734.0
ST13	-7144.0	7998.0
STAT3	8126.0	4982.0
STIP1	-7236.0	7449.0
SUZ12	-1028.0	8662.0
SZT2	-3750.0	-6450.0
TCIRG1	-5363.0	-3931.0
TERF1	-6043.0	4260.0
TERF2	5515.0	5270.0
TERF2IP	-2169.0	2046.0
TFDP1	-6289.0	4476.0
TFDP2	7449.0	3780.0
TINF2	2114.0	2374.0
TNFRSF21	7819.0	3310.0
TNIK	2227.0	4457.0
TNRC6A	4450.0	-2617.0
TNRC6B	613.0	-4375.0
TNRC6C	2604.0	-4658.0
TP53	2557.0	-3561.0
TPR	-4239.0	8611.0
TRIB3	3661.0	-614.0
TXN	-5397.0	-2909.0
TXN2	-2656.0	1641.0
TXNRD1	-3425.0	4896.0
TXNRD2	-2117.0	-5805.0
UBA52	7488.0	-4269.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
UBE2C	733.0	-1864.0
UBE2D1	5638.0	3025.0
UBE2D2	-935.0	6690.0
UBE2D3	-5084.0	8317.0
UBE2E1	-6831.0	8405.0
UBE2S	4549.0	-1742.0
UBN1	-3031.0	-5794.0
VCP	-7069.0	5449.0
VEGFA	-4619.0	-5156.0
WDR24	-1198.0	568.0
WDR59	-2025.0	-4156.0
WTIP	-4878.0	-1899.0
YWHAE	-2079.0	7315.0

---

---

Neutrophil degranulation

Neutrophil degranulation

metric	value
setSize	416
pMANOVA	2.06e-09
p.adjustMANOVA	8.77e-08
s.dist	0.189
s.diabetes	-0.0558
s.mitoG	0.18
p.diabetes	0.0519
p.mitoG	3.1e-10

Top 20 genes

Gene	diabetes	mitoG
MNDA	-7345.0	8836.0
HSP90AA1	-7286.0	8742.0
PNP	-7335.0	8459.0
ERP44	-7159.0	8460.0
HSPA8	-7307.0	8180.0
RAP1A	-6787.0	8805.0
DNAJC3	-7149.0	8179.0
PSMD1	-6497.0	8619.0
SNAP29	-7150.0	7785.0
LILRB3	-7184.0	7732.0
RAB6A	-6370.0	8664.0
DYNLL1	-6952.0	7645.0
PSMD12	-6149.0	8628.0
HSPA1A	-7272.5	7293.5
HSPA1B	-7272.5	7293.5
PSMD7	-6943.0	7625.0
MAGT1	-6822.0	7703.0
ADAM10	-6444.0	8149.0
SNAP23	-6477.0	8059.0
PSMD14	-6080.0	8262.0

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
ABCA13	7345.0	5289.0
ACAA1	7141.0	-6777.0
ACLY	394.0	2995.0
ACP3	4267.0	4720.0
ACTR10	268.0	6666.0
ACTR1B	1842.0	570.0
ACTR2	-5189.0	7356.0
ADAM10	-6444.0	8149.0
ADAM8	-5171.0	-1538.0
ADGRE5	-2363.0	6199.0
ADGRG3	6332.0	-5786.0
AGA	2406.0	-3450.0
AGL	6768.0	2825.0
AGPAT2	-4051.0	-2429.0
ALAD	2122.0	-5915.0
ALDH3B1	7287.0	4258.0
ALDOA	6979.5	3652.5
ALDOC	8058.0	-926.0
ALOX5	5079.0	-1468.0
AMPD3	7453.0	2602.0
ANO6	-6150.0	7153.0
ANPEP	3600.0	1770.0
ANXA2	-337.0	8406.0
AOC1	5592.0	-5405.0
AP1M1	2796.0	-3928.0
AP2A2	-6231.0	249.0
APAF1	-1681.0	4531.0
APEH	328.0	-4272.0
APRT	7257.0	-2499.0
ARG1	203.0	-1236.0
ARHGAP9	-425.0	-2275.0
ARL8A	1646.0	-4501.0
ARMC8	2586.0	6569.0
ARPC5	920.0	7514.0
ARSA	4080.0	-2367.0
ARSB	-5231.0	2994.0
ASAH1	-720.0	8441.0
ATG7	7859.0	-906.0
ATP11A	-7323.0	505.0
ATP11B	2684.0	5073.0
ATP6AP2	596.0	3605.0
ATP6V0A1	936.0	1549.0
ATP6V0C	1078.0	-2076.0
ATP6V1D	-3259.0	8108.0
ATP8A1	-2763.0	5337.0
ATP8B4	-4965.0	-4796.0
B2M	5339.0	4978.0
B4GALT1	-356.0	-3621.0
BIN2	-3519.0	1037.0
BRI3	3478.0	-3699.0
BST1	5884.0	6856.0
BST2	-460.0	-4229.0
C3	7675.0	3404.0
C3AR1	-1253.0	7488.0
C5AR1	-2161.0	5951.0
C6orf120	-2826.0	7321.0
CAB39	725.0	7364.0
CAND1	-6336.0	3476.0
CANT1	6496.0	-5371.0
CAP1	-1701.0	6877.0
CAPN1	7308.0	-2267.0
CAT	-602.0	4907.0
CCT2	-5508.0	4188.0
CCT8	-6214.0	2208.0
CD14	4081.0	6994.0
CD300A	-4313.5	171.5
CD33	-6278.5	7868.5
CD36	-7328.0	6006.0
CD44	-4381.0	6982.0
CD47	-1991.0	7809.0
CD53	-3501.0	7525.0
CD55	-6863.0	6749.0
CD59	5509.5	-1796.5
CD63	-5955.0	5945.0
CD93	-3514.0	7897.0
CDA	4457.0	-5554.0
CDK13	-1373.0	3872.0
CEACAM1	3793.5	5357.5
CEACAM3	3793.5	5357.5
CEACAM6	3793.5	5357.5
CEACAM8	3793.5	5357.5
CEP290	-2988.0	5308.0
CFD	6928.0	-5898.0
CFP	-3458.0	-5006.0
CHI3L1	3964.0	708.0
CHRNB4	-377.0	-3200.0
CKAP4	4629.0	6520.0
CLEC12A	-2696.0	5068.0
CLEC4C	-6182.0	-5563.0
CLEC5A	1408.0	5146.0
CMTM6	-6996.0	-940.0
CNN2	-2669.0	6553.0
COMMD3	-4289.0	8822.0
COMMD9	-1892.0	-1552.0
COPB1	-2848.0	7946.0
COTL1	8183.0	-5409.0
CPNE1	4530.0	-1637.0
CPNE3	1709.0	7633.0
CPPED1	-6207.0	6376.0
CR1	-4680.0	4418.0
CRACR2A	-766.0	-6429.0
CREG1	5600.0	3619.0
CRISPLD2	4467.0	8306.0
CSNK2B	-3628.0	6622.0
CST3	2605.0	4686.0
CSTB	6639.0	3948.0
CTSA	6070.0	1611.0
CTSB	7086.0	-1439.0
CTSC	-1974.0	7696.0
CTSD	5035.5	6716.5
CTSH	-6661.0	6547.0
CTSS	-5861.0	7572.0
CTSZ	-2861.0	2478.0
CXCR2	-4298.0	3063.0
CYB5R3	1442.0	4432.0
CYBA	-4719.0	-4200.0
CYBB	-5520.0	5307.0
CYFIP1	3175.0	7476.0
CYSTM1	-3557.0	5741.0
DBNL	3890.0	-1155.0
DDOST	-5017.0	2674.0
DDX3X	3775.0	8058.0
DEGS1	-4450.0	2479.0
DERA	5742.0	3035.0
DGAT1	5332.0	-6609.0
DIAPH1	7761.0	3677.0
DNAJC13	-5891.0	-1362.0
DNAJC3	-7149.0	8179.0
DNAJC5	4458.0	5657.0
DNASE1L1	5513.0	-281.0
DOCK2	-5657.0	5085.0
DOK3	-3879.0	-2058.0
DPP7	-7293.0	-6577.0
DSN1	6293.0	388.0
DSP	7655.0	6828.0
DYNC1H1	4822.0	2594.0
DYNC1LI1	2249.0	7292.0
DYNLL1	-6952.0	7645.0
DYNLT1	8238.0	-3740.0
EEF2	-3312.0	2063.0
ENPP4	1750.0	7383.0
ERP44	-7159.0	8460.0
FABP5	3630.0	2188.0
FAF2	-379.0	-899.0
FCER1G	-3782.0	3932.0
FCGR2A	-7297.0	5966.0
FCGR3B	-5407.5	6212.5
FGL2	-5183.0	7853.0
FGR	-3144.0	378.0
FLG2	7956.0	-6285.0
FOLR3	4808.5	-5490.5
FRK	1843.0	5921.0
FRMPD3	-5834.0	-2578.0
FTL	-6693.0	-6771.0
FUCA1	-2319.0	5869.0
FUCA2	-6780.0	1532.0
GAA	-3821.0	-2398.0
GALNS	-6518.0	51.0
GCA	5307.0	2556.0
GDI2	-5894.0	8074.0
GGH	6841.0	4657.0
GHDC	1575.0	-4841.0
GLA	1196.0	3449.0
GLB1	-5376.0	2645.0
GLIPR1	-4306.0	6128.0
GM2A	7424.0	6766.0
GMFG	3969.0	7186.0
GNS	8072.0	1691.0
GOLGA7	-2069.0	6586.0
GPI	4816.0	5422.0
GRN	-4733.0	-4582.0
GSDMD	1017.0	-1040.0
GSN	7535.0	7997.0
GSTP1	1683.0	2544.0
GUSB	-7203.0	1338.0
GYG1	27.0	6415.0
HEBP2	4787.0	3455.0
HEXB	-6611.0	-740.0
HGSNAT	6373.0	2744.0
HK3	-4874.0	2139.0
HMGB1	2876.0	8283.0
HMOX2	-1566.0	6596.0
HP	-1369.5	6104.5
HPSE	50.0	-1095.0
HRNR	8095.0	-6305.0
HSP90AA1	-7286.0	8742.0
HSP90AB1	-7306.0	5626.0
HSPA1A	-7272.5	7293.5
HSPA1B	-7272.5	7293.5
HSPA8	-7307.0	8180.0
HUWE1	-6141.0	3624.0
HVCN1	-791.0	2937.0
IDH1	5264.0	7348.0
IGF2R	7820.0	-602.0
ILF2	2872.0	3070.0
IMPDH1	1190.0	4821.0
IMPDH2	4946.0	4658.0
IQGAP1	7427.0	8123.0
IQGAP2	8068.0	6890.0
IRAG2	-1956.0	-783.0
IST1	4515.0	-3732.0
ITGAL	-4315.0	-1137.0
ITGAM	3292.0	5515.0
ITGAV	8155.0	2693.0
ITGAX	-5859.0	2296.0
ITGB2	-5238.0	412.0
JUP	4751.0	2870.0
KCMF1	-2107.0	6464.0
KCNAB2	-1327.0	724.0
KPNB1	-1668.0	5829.0
LAIR1	-5670.0	-3164.0
LAMP1	664.0	4209.0
LAMP2	-4970.0	6952.0
LAMTOR1	-81.0	-630.0
LAMTOR2	-2847.0	1280.0
LAMTOR3	2323.0	4870.0
LCN2	5811.0	8293.0
LGALS3	7090.0	5330.0
LILRB3	-7184.0	7732.0
LPCAT1	-6277.0	7035.0
LRG1	2288.0	4889.0
LRRC7	-883.0	-2663.0
LTA4H	-1869.0	3373.0
LTF	-2111.0	1638.0
MAGT1	-6822.0	7703.0
MAN2B1	-3804.0	-5934.0
MANBA	-5693.0	-5502.0
MAPK1	-3928.0	6920.0
MAPK14	-6337.0	-1012.0
MCEMP1	-5291.0	6726.0
METTL7A	1647.0	-266.0
MGAM	561.0	417.0
MGST1	7252.0	4639.0
MIF	8230.0	5317.0
MLEC	-7059.0	-620.0
MME	-2831.0	3783.0
MMP25	525.0	-6432.0
MMP9	-5717.0	1502.0
MNDA	-7345.0	8836.0
MOSPD2	-1998.0	8209.0
MPO	892.0	-1006.0
MVP	6785.0	-5147.0
NAPRT	3730.0	-6610.0
NBEAL2	6989.0	-6392.0
NCKAP1L	-1592.0	4630.0
NCSTN	6534.0	860.0
NDUFC2	4564.5	-5546.5
NEU1	-4896.0	-6581.0
NFAM1	-5168.0	2355.0
NFASC	-6650.0	-793.0
NFKB1	5449.0	4035.0
NHLRC3	2688.0	-1139.0
NIT2	-5666.0	-1701.0
NME2	-3826.0	-2887.0
NPC2	3922.0	3679.0
NRAS	3837.0	7903.0
OLFM4	6940.0	-1244.0
OLR1	-1782.0	2913.0
ORM1	3867.5	-4259.5
ORM2	3867.5	-4259.5
ORMDL3	5642.0	-2453.0
OSCAR	2024.0	-1438.0
OSTF1	6553.0	5854.0
P2RX1	1145.0	5033.0
PA2G4	-2524.5	7069.5
PADI2	-2608.0	-2165.0
PAFAH1B2	-1657.0	7964.0
PDAP1	3245.0	700.0
PDXK	8266.0	-2949.0
PECAM1	3970.0	8677.0
PFKL	7340.0	-4515.0
PGAM1	1992.0	4530.0
PGLYRP1	-1223.0	-3101.0
PGM1	-1081.0	5048.0
PGM2	7401.0	7591.0
PGRMC1	8184.0	7942.0
PIGR	-1209.0	-4257.0
PKM	7561.0	7758.0
PLAC8	6334.0	-3893.0
PLAU	-5613.0	-5199.0
PLAUR	4004.0	6827.0
PLD1	-4824.0	-1222.0
PLEKHO2	-1522.5	7084.5
PNP	-7335.0	8459.0
PPBP	-5336.0	4394.0
PPIA	4868.0	-469.0
PPIE	6275.0	-5627.0
PRCP	-6663.0	1095.0
PRDX4	-68.0	-1128.0
PRDX6	-3287.0	3877.0
PRKCD	365.0	1901.0
PRSS2	-2444.0	-3110.0
PRSS3	-2444.0	-3110.0
PSAP	6220.0	-3472.0
PSEN1	-7020.0	6996.0
PSMA2	-5464.5	6058.5
PSMA5	-6660.0	4497.0
PSMB1	-5281.0	5936.0
PSMB7	-4628.0	-657.0
PSMC2	-6765.0	4648.0
PSMC3	-4285.0	3386.0
PSMD1	-6497.0	8619.0
PSMD11	-6873.0	5201.0
PSMD12	-6149.0	8628.0
PSMD13	1898.0	5044.0
PSMD14	-6080.0	8262.0
PSMD2	-6702.0	-3836.0
PSMD3	-2532.0	-3242.0
PSMD6	-6385.0	6157.0
PSMD7	-6943.0	7625.0
PTAFR	-5062.0	6031.0
PTGES2	5575.0	-1828.0
PTPN6	-1098.0	2140.0
PTPRB	3085.0	8717.0
PTPRC	-7112.0	6863.0
PTPRJ	3203.0	5737.0
PTPRN2	5657.0	877.0
PTX3	-4488.0	-2545.0
PYCARD	6548.0	-4704.0
PYGB	5808.0	5273.0
PYGL	6729.0	1748.0
QPCT	2060.0	2678.0
QSOX1	7456.0	1100.0
RAB10	-5609.0	8060.0
RAB14	-4203.0	5569.0
RAB18	-6358.0	6912.0
RAB24	4481.0	-5649.0
RAB27A	7997.0	1512.0
RAB31	3839.0	8541.0
RAB37	1244.0	-5646.0
RAB3A	-21.0	-1948.0
RAB3D	6472.0	4535.0
RAB4B	6400.5	-1765.5
RAB5B	5887.0	3206.0
RAB5C	3703.0	3375.0
RAB6A	-6370.0	8664.0
RAB7A	-5898.0	8083.0
RAC1	-1258.0	4008.0
RAP1A	-6787.0	8805.0
RAP1B	942.0	8759.0
RAP2B	5671.0	-1178.0
RAP2C	-4441.0	2874.0
RETN	-1704.0	-1106.0
RHOA	-5203.0	7671.0
RHOF	5184.0	-2496.0
RHOG	2039.0	1654.0
RNASE2	5113.5	-4405.5
RNASE3	5113.5	-4405.5
RNASET2	8101.5	-6540.5
ROCK1	-2765.0	8654.0
S100A11	4838.0	7913.0
S100A8	-3981.0	6893.0
SCAMP1	7264.0	2855.0
SDCBP	5668.0	4540.0
SELL	-4022.0	902.0
SERPINA1	8234.0	4905.0
SERPINA3	2345.0	8095.0
SERPINB1	7293.0	4143.0
SERPINB10	4371.0	-319.0
SERPINB6	7950.0	8360.0
SIGLEC9	-2039.5	-2039.5
SIRPA	-6193.5	-6693.5
SIRPB1	-6193.5	-6693.5
SLC11A1	-1742.0	815.0
SLC15A4	-6120.0	-5883.0
SLC27A2	-6940.0	532.0
SLC2A5	8118.0	4882.0
SLC44A2	7940.0	4899.0
SLCO4C1	1461.0	-992.0
SLPI	307.0	3136.0
SNAP23	-6477.0	8059.0
SNAP29	-7150.0	7785.0
SPTAN1	7051.0	7359.0
SRP14	372.0	5948.0
STBD1	-6692.0	3728.0
STING1	-266.0	6780.0
STK10	-1779.0	2392.0
STK11IP	7069.0	-5659.0
STOM	2062.0	8033.0
SURF4	-5939.0	2804.0
SVIP	-1801.0	4362.0
SYNGR1	6225.0	-2427.0
TARM1	6276.0	2422.0
TBC1D10C	4785.0	-3612.0
TCIRG1	-5363.0	-3931.0
TIMP2	4104.0	8646.0
TLR2	5407.0	5188.0
TMBIM1	5555.0	2568.0
TMC6	-5597.0	-5013.0
TMEM179B	-3249.0	-2550.0
TMEM30A	-6557.0	6632.0
TMEM63A	7912.0	1.0
TNFAIP6	-3592.0	4376.0
TNFRSF1B	-5427.0	939.0
TOLLIP	5721.0	3964.0
TOM1	-2514.0	-174.0
TRAPPC1	-1429.0	4746.0
TRPM2	-2904.0	-6037.0
TSPAN14	-6627.0	1158.0
TTR	-6090.0	3451.0
TUBB	335.0	8036.0
TUBB4B	-5222.0	8679.0
TXNDC5	1391.0	-669.0
TYROBP	-4245.0	2276.0
UBR4	4082.0	-4874.0
UNC13D	12.0	-5070.0
VAMP8	-3005.0	5301.0
VAPA	-4422.0	7382.0
VAT1	7581.0	-4263.0
VCL	-4796.0	7947.0
VCP	-7069.0	5449.0
VNN1	6246.0	7250.0
VPS35L	968.0	-5964.0
XRCC5	-2388.0	162.0
XRCC6	-1971.0	4034.0
YPEL5	8001.0	3939.0

---

---

Major pathway of rRNA processing in the nucleolus and cytosol

Major pathway of rRNA processing in the nucleolus and cytosol

metric	value
setSize	145
pMANOVA	2.19e-09
p.adjustMANOVA	9.05e-08
s.dist	0.287
s.diabetes	0.0502
s.mitoG	0.282
p.diabetes	0.298
p.mitoG	4.49e-09

Top 20 genes

Gene	diabetes	mitoG
NCL	6850.0	8762.0
RPL35	5949.0	8834.0
FAU	6809.0	7710.0
UTP20	8200.0	5794.0
XRN2	7433.0	6374.0
RPS15	7253.0	6174.0
RPS17	5667.0	7685.0
NIP7	5420.0	6991.0
RPS25	4261.0	8455.0
EXOSC9	4661.0	7068.0
RRP1	5293.0	6186.0
UTP15	4856.0	6673.0
RPL28	6714.0	4753.0
RPL26	3650.0	8722.0
RPL38	5601.0	5675.0
RPL19	4654.0	6782.0
RPS2	7322.0	4216.0
RPS8	3874.0	7646.0
RPS5	3848.0	7515.0
CSNK1E	5383.5	5055.5

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
BMS1	-5831.0	3306.0
BOP1	-3585.0	976.0
BYSL	-4542.0	5843.0
C1D	-5321.0	8041.0
CSNK1D	-1602.0	2506.0
CSNK1E	5383.5	5055.5
DCAF13	-6109.0	5418.0
DDX21	-5116.0	8276.0
DDX47	3030.0	755.0
DDX49	4404.0	-1145.0
DDX52	-4060.0	7194.0
DHX37	-533.0	-1936.0
DIS3	-6175.0	6931.0
EBNA1BP2	-2177.0	6468.0
EMG1	-6093.0	-1167.0
ERI1	-5053.0	4453.0
EXOSC1	-2448.0	7613.0
EXOSC10	1760.0	8346.0
EXOSC2	3957.0	3800.0
EXOSC3	-1469.0	-3935.0
EXOSC4	-3182.0	-4923.0
EXOSC5	4223.0	-3378.0
EXOSC7	6973.0	-5606.0
EXOSC8	6788.0	616.0
EXOSC9	4661.0	7068.0
FAU	6809.0	7710.0
FBL	6041.0	-6202.0
FTSJ3	364.0	-330.0
GNL3	-4340.0	6867.0
HEATR1	-6514.0	7682.0
IMP3	3952.0	-6093.0
IMP4	186.0	5570.0
ISG20L2	-4479.0	3406.0
KRR1	-4385.0	7088.0
LAS1L	1684.0	1715.0
LTV1	-279.5	6894.5
MPHOSPH10	-5904.0	8696.0
MPHOSPH6	-3203.0	7923.0
MTREX	-6973.0	5247.0
NCL	6850.0	8762.0
NIP7	5420.0	6991.0
NOB1	-3003.0	2527.0
NOC4L	5961.0	1908.0
NOL11	-4046.0	6580.0
NOL12	-3477.5	6109.5
NOL6	7943.0	-3108.0
NOL9	-1832.0	-148.0
NOP14	-2312.0	6526.0
NOP56	-875.0	1129.0
NOP58	-4438.0	5964.0
PDCD11	-4002.0	-3015.0
PELP1	1681.0	-4851.0
PES1	2890.0	6091.0
PNO1	-5524.0	8385.0
PWP2	4987.5	-4444.5
RBM28	-5098.0	2336.0
RCL1	5218.0	4620.0
RIOK1	-1297.0	7015.0
RIOK2	-670.0	7303.0
RIOK3	-3202.0	8097.0
RPL11	5748.0	1403.0
RPL12	6107.0	-5604.0
RPL13	5686.0	-3760.0
RPL14	5110.0	-1875.0
RPL18	2523.0	-625.0
RPL18A	4545.0	-3218.0
RPL19	4654.0	6782.0
RPL21	-1686.0	8463.0
RPL22	2365.0	459.0
RPL22L1	-5123.0	-6294.0
RPL23	-205.0	4253.0
RPL24	-409.0	6813.0
RPL26	3650.0	8722.0
RPL28	6714.0	4753.0
RPL29	2613.0	4628.0
RPL3	5378.0	1155.0
RPL30	4372.0	3664.0
RPL31	6732.0	-1507.0
RPL32	2989.0	8728.0
RPL34	661.0	7140.0
RPL35	5949.0	8834.0
RPL35A	-1509.0	6565.0
RPL36	7543.0	-2424.0
RPL36A	-5983.0	4837.0
RPL36AL	1793.0	-2074.0
RPL37	2109.0	-667.0
RPL38	5601.0	5675.0
RPL3L	-5986.0	4937.0
RPL4	2582.0	8471.0
RPL6	572.0	7594.0
RPL7	-5186.0	8598.0
RPL8	3526.0	820.0
RPLP2	3550.0	3555.0
RPP14	-1705.0	2028.0
RPP21	1368.0	437.0
RPP25	5432.0	3890.0
RPP30	-4567.0	4289.0
RPP38	-3284.0	7004.0
RPP40	-5546.0	2654.0
RPS13	7174.0	315.0
RPS14	4070.0	4443.0
RPS15	7253.0	6174.0
RPS16	6244.0	1119.0
RPS17	5667.0	7685.0
RPS18	4253.0	-526.0
RPS19	6565.0	-1215.0
RPS2	7322.0	4216.0
RPS21	7111.0	-6494.0
RPS25	4261.0	8455.0
RPS27A	-133.0	-1807.0
RPS28	7208.0	-396.0
RPS3	2340.0	4381.0
RPS3A	-3115.0	8824.0
RPS4X	2522.0	7391.0
RPS5	3848.0	7515.0
RPS6	-1700.0	8603.0
RPS8	3874.0	7646.0
RPS9	-1719.0	-2555.0
RRP1	5293.0	6186.0
RRP36	3453.0	244.0
RRP7A	-1466.0	3721.0
RRP9	2614.0	851.0
SENP3	-2124.5	3519.5
SNU13	-4083.0	7577.0
TBL3	5799.0	-3253.0
TEX10	5529.0	1840.0
TSR1	-4634.0	2623.0
UBA52	7488.0	-4269.0
UTP11	-3324.0	3075.0
UTP14A	-755.5	3859.5
UTP14C	-755.5	3859.5
UTP15	4856.0	6673.0
UTP18	1908.0	6014.0
UTP20	8200.0	5794.0
UTP3	-2706.0	6844.0
UTP4	-4384.0	4038.0
UTP6	-3727.0	5591.0
WDR12	-3943.0	1434.0
WDR18	-5000.0	-3150.0
WDR3	-6076.0	2575.0
WDR36	5285.0	-1626.0
WDR43	2708.0	8166.0
WDR46	5078.0	-4710.0
WDR75	-3646.0	8219.0
XRN2	7433.0	6374.0

---

---

Defective CFTR causes cystic fibrosis

Defective CFTR causes cystic fibrosis

metric	value
setSize	60
pMANOVA	2.63e-09
p.adjustMANOVA	1.05e-07
s.dist	0.51
s.diabetes	-0.429
s.mitoG	0.276
p.diabetes	8.76e-09
p.mitoG	0.000221

Top 20 genes

Gene	diabetes	mitoG
PSMC6	-6851.0	8666.0
UBB	-7104.0	8341.0
PSME4	-6830.0	8511.0
PSMD1	-6497.0	8619.0
SEL1L	-7264.0	7670.0
PSMD12	-6149.0	8628.0
PSMD7	-6943.0	7625.0
PSMA1	-6705.0	7838.0
UBC	-6013.0	8514.0
PSMC4	-6423.0	7920.0
PSMD14	-6080.0	8262.0
DERL2	-7153.0	6854.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
VCP	-7069.0	5449.0
PSMD11	-6873.0	5201.0
ERLIN1	-7147.0	4833.0
CFTR	-6902.0	4865.0
PSMA2	-5464.5	6058.5
ERLEC1	-3854.0	8504.0

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
CFTR	-6902.0	4865.0
DERL1	-5101.0	3639.0
DERL2	-7153.0	6854.0
DERL3	-4530.0	-5374.0
ERLEC1	-3854.0	8504.0
ERLIN1	-7147.0	4833.0
ERLIN2	-5110.0	-648.0
OS9	-5615.0	3279.0
PSMA1	-6705.0	7838.0
PSMA2	-5464.5	6058.5
PSMA3	-3145.0	7801.0
PSMA4	-6074.0	4688.0
PSMA5	-6660.0	4497.0
PSMA6	-1954.0	8445.0
PSMA7	1612.0	7052.0
PSMA8	649.0	-4004.0
PSMB1	-5281.0	5936.0
PSMB10	3752.0	-908.0
PSMB11	1977.0	-5501.0
PSMB2	1472.0	-4144.0
PSMB3	-3388.0	5539.0
PSMB4	-4941.0	-5852.0
PSMB5	-1638.0	-2409.0
PSMB6	1806.0	-1845.0
PSMB7	-4628.0	-657.0
PSMB8	1080.0	-3793.0
PSMB9	5987.0	-4708.0
PSMC1	-1312.0	4327.0
PSMC2	-6765.0	4648.0
PSMC3	-4285.0	3386.0
PSMC4	-6423.0	7920.0
PSMC5	-4831.0	1120.0
PSMC6	-6851.0	8666.0
PSMD1	-6497.0	8619.0
PSMD10	-1613.0	2576.0
PSMD11	-6873.0	5201.0
PSMD12	-6149.0	8628.0
PSMD13	1898.0	5044.0
PSMD14	-6080.0	8262.0
PSMD2	-6702.0	-3836.0
PSMD3	-2532.0	-3242.0
PSMD4	-5648.0	4994.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
PSMD7	-6943.0	7625.0
PSMD8	1978.0	7546.0
PSMD9	7707.5	-894.5
PSME1	2907.0	5905.0
PSME2	1270.0	-4595.0
PSME3	752.0	7366.0
PSME4	-6830.0	8511.0
PSMF1	5087.0	4771.0
RNF185	2705.0	5366.0
RNF5	-1555.0	-4449.0
RPS27A	-133.0	-1807.0
SEL1L	-7264.0	7670.0
UBA52	7488.0	-4269.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
VCP	-7069.0	5449.0

---

---

Cell surface interactions at the vascular wall

Cell surface interactions at the vascular wall

metric	value
setSize	132
pMANOVA	3.12e-09
p.adjustMANOVA	1.22e-07
s.dist	0.315
s.diabetes	-0.0327
s.mitoG	0.314
p.diabetes	0.517
p.mitoG	4.94e-10

Top 20 genes

Gene	diabetes	mitoG
IGHV1-69	-7353.5	8845.5
IGKV4-1	-7301.0	8840.0
ITGB1	-6241.0	8758.0
ANGPT1	-6415.0	8155.0
SDC2	-6850.0	7623.0
IGKV5-2	-5895.0	8671.0
THBD	-6500.0	7788.0
SOS1	-6566.0	7698.0
SELPLG	-5767.0	7976.0
SLC16A1	-7027.0	5763.0
LYN	-4685.0	8216.0
IGHA1	-5036.5	7384.5
IGHA2	-5036.5	7384.5
CD44	-4381.0	6982.0
JAM2	-4044.0	6849.0
GYPA	-4292.0	6256.0
GYPB	-4292.0	6256.0
PTPN11	-3946.0	6142.0
CXADR	-7100.0	3254.0
ANGPT4	-4077.0	5377.0

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
ANGPT1	-6415.0	8155.0
ANGPT2	3174.0	4727.0
ANGPT4	-4077.0	5377.0
APOB	7604.0	5782.0
ATP1B1	8146.0	7502.0
ATP1B2	-1075.0	6478.0
ATP1B3	-1025.0	8436.0
BSG	-3166.0	5032.0
CAV1	875.0	7970.0
CD2	-1746.0	-1924.0
CD244	-260.0	-5097.0
CD44	-4381.0	6982.0
CD47	-1991.0	7809.0
CD48	-1928.0	2626.0
CD74	-4460.0	2932.0
CD84	-1375.0	5042.0
CD99L2	-6579.0	522.0
CEACAM1	3793.5	5357.5
CEACAM3	3793.5	5357.5
CEACAM5	3793.5	5357.5
CEACAM6	3793.5	5357.5
CEACAM8	3793.5	5357.5
CXADR	-7100.0	3254.0
DOK2	3914.0	1693.0
EPCAM	7886.0	5746.0
ESAM	5409.0	5821.0
F11R	2367.0	6083.0
F2	-3087.0	4699.0
FCAMR	-7326.0	-1528.0
FCER1G	-3782.0	3932.0
FN1	7489.0	8379.0
FYN	-2200.0	6221.0
GAS6	7430.0	-2362.0
GLG1	-3103.0	2134.0
GP6	-4788.0	-1728.0
GPC1	7890.0	581.0
GRB14	6642.0	2356.0
GRB2	3285.0	1922.0
GRB7	-6981.0	-4231.0
GYPA	-4292.0	6256.0
GYPB	-4292.0	6256.0
GYPC	6613.0	-1072.0
HRAS	1503.0	-318.0
IGHA1	-5036.5	7384.5
IGHA2	-5036.5	7384.5
IGHM	5659.0	-3544.0
IGHV1-69	-7353.5	8845.5
IGHV2-5	4395.0	4965.0
IGHV2-70	4395.0	4965.0
IGHV7-81	517.5	7570.5
IGKC	-2925.0	7318.0
IGKV1-12	2052.5	4944.5
IGKV1-17	2052.5	4944.5
IGKV1-39	2052.5	4944.5
IGKV1D-12	2052.5	4944.5
IGKV1D-39	2052.5	4944.5
IGKV2-30	101.5	8396.5
IGKV2D-30	101.5	8396.5
IGKV4-1	-7301.0	8840.0
IGKV5-2	-5895.0	8671.0
IGLL1	-968.0	8657.0
IGLV4-60	-3537.5	3617.5
IGLV4-69	-3537.5	3617.5
INPP5D	-1230.0	5535.0
ITGA3	6960.0	5200.0
ITGA4	-6762.0	7.0
ITGA5	5929.0	6964.0
ITGA6	-6617.0	2201.0
ITGAL	-4315.0	-1137.0
ITGAM	3292.0	5515.0
ITGAV	8155.0	2693.0
ITGAX	-5859.0	2296.0
ITGB1	-6241.0	8758.0
ITGB2	-5238.0	412.0
ITGB3	1530.5	4298.5
JAM2	-4044.0	6849.0
JAM3	-6751.0	625.0
JCHAIN	-1963.0	6913.0
KRAS	-752.0	8587.0
L1CAM	7726.0	3102.0
LCK	-2194.0	5687.0
LYN	-4685.0	8216.0
MAG	-121.0	-2059.0
MERTK	2880.0	6387.0
MIF	8230.0	5317.0
NRAS	3837.0	7903.0
OLR1	-1782.0	2913.0
PECAM1	3970.0	8677.0
PICK1	5109.0	-6104.0
PIK3CA	-6347.0	2923.0
PIK3CB	-1756.0	1880.0
PIK3R1	-839.0	8363.0
PIK3R2	1669.5	-3969.5
PLCG1	8067.0	-4962.0
PPIA	4868.0	-469.0
PPIL2	-2624.0	2317.0
PROCR	2059.0	3834.0
PROS1	4907.0	7279.0
PTPN11	-3946.0	6142.0
PTPN6	-1098.0	2140.0
SDC1	6076.0	6227.0
SDC2	-6850.0	7623.0
SDC3	5919.0	4486.0
SDC4	6585.0	816.0
SELE	3067.0	6535.0
SELL	-4022.0	902.0
SELP	5864.0	2861.0
SELPLG	-5767.0	7976.0
SHC1	568.0	1962.0
SIRPA	-6193.5	-6693.5
SIRPG	-6193.5	-6693.5
SLC16A1	-7027.0	5763.0
SLC16A3	5619.0	-3522.0
SLC16A8	87.0	-4934.0
SLC3A2	7436.0	1396.0
SLC7A10	60.0	-1732.0
SLC7A11	-1418.0	-2975.0
SLC7A5	6666.0	-84.0
SLC7A6	4355.0	5198.0
SLC7A7	6551.0	-5468.0
SLC7A8	7330.0	-3995.0
SLC7A9	6467.0	-6401.0
SOS1	-6566.0	7698.0
SPN	5031.0	-1295.0
SRC	-2657.0	-1643.0
TEK	-2265.0	8575.0
TGFB1	-1851.0	6152.0
THBD	-6500.0	7788.0
TREM1	169.0	-2242.0
TSPAN7	4302.5	3267.5
VPREB1	672.0	1924.0
YES1	-120.0	7265.0

---

---

Cellular responses to stress

Cellular responses to stress

metric	value
setSize	465
pMANOVA	3.24e-09
p.adjustMANOVA	1.23e-07
s.dist	0.167
s.diabetes	-0.00236
s.mitoG	0.166
p.diabetes	0.931
p.mitoG	8.88e-10

Top 20 genes

Gene	diabetes	mitoG
HSP90AA1	-7286.0	8742.0
PTGES3	-7067.0	8733.0
HSPA4L	-7193.0	8500.0
HSPA8	-7307.0	8180.0
PSMC6	-6851.0	8666.0
UBB	-7104.0	8341.0
CAPZA1	-6942.0	8474.0
PSME4	-6830.0	8511.0
UBE2E1	-6831.0	8405.0
ST13	-7144.0	7998.0
HSPA13	-7108.0	8023.0
PSMD1	-6497.0	8619.0
PRDX1	-6422.0	8698.0
HSPA5	-7309.0	7589.0
HSPA4	-6676.0	8292.0
STIP1	-7236.0	7449.0
DYNLL1	-6952.0	7645.0
PSMD12	-6149.0	8628.0
CUL2	-6236.0	8506.0
HSPA1A	-7272.5	7293.5

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
AAAS	5561.0	-2261.0
ACD	5902.0	-6561.0
ACTR10	268.0	6666.0
ACTR1A	965.0	5035.0
AGO1	6080.0	-4094.0
AGO3	-1670.0	-1990.0
AGO4	2726.0	6474.0
AJUBA	-194.0	-1290.0
AKT1S1	3062.0	-5699.0
ANAPC1	-6298.0	2903.0
ANAPC10	-1783.0	4951.0
ANAPC15	4299.0	155.0
ANAPC16	2.0	1444.0
ANAPC2	-3336.0	-4659.0
ANAPC4	6315.0	5808.0
ANAPC5	6285.0	-1473.0
ANAPC7	5249.0	-3454.0
AQP8	-3980.0	1683.0
AR	2841.0	2349.0
ARNT	1247.0	2255.0
ASF1A	-4510.0	7034.0
ASNS	419.0	3160.0
ATF2	-4162.0	7780.0
ATF3	-845.0	6400.0
ATF4	-6143.0	7857.0
ATF5	342.0	3756.0
ATM	5701.0	-2536.0
ATOX1	8025.0	-3520.0
ATP6V0B	-1247.0	-3182.0
ATP6V0C	1078.0	-2076.0
ATP6V0D1	-3890.0	3817.0
ATP6V0D2	3320.0	5793.0
ATP6V0E1	1832.0	3873.0
ATP6V0E2	158.0	-4784.0
ATP6V1A	4631.0	5077.0
ATP6V1B1	7324.0	-1200.0
ATP6V1B2	2487.0	2135.0
ATP6V1C1	-3690.0	-528.0
ATP6V1C2	3469.0	5006.0
ATP6V1D	-3259.0	8108.0
ATP6V1E1	-704.0	8548.0
ATP6V1F	5567.0	1498.0
ATP6V1G1	7327.0	4738.0
ATP6V1G2	-2452.0	921.0
ATP6V1G3	-2690.0	4036.0
ATP6V1H	-1095.0	8501.0
ATP7A	-3222.0	7692.0
ATR	234.0	5001.0
BAG1	2254.0	6318.0
BAG2	6922.0	3368.0
BAG3	-6860.0	6695.0
BAG4	7654.0	5147.0
BAG5	-2637.0	8168.0
BMI1	-4453.5	8309.5
BMT2	-4495.0	6954.0
C12orf66	5492.0	-1861.0
CA9	-2361.0	-2782.0
CABIN1	5467.0	-5948.0
CAMK2A	-2272.0	4664.0
CAMK2B	2551.0	5253.0
CAMK2G	5581.0	-3540.0
CAPZA1	-6942.0	8474.0
CAPZA2	-1687.0	8135.0
CAPZB	-2513.0	7203.0
CAT	-602.0	4907.0
CBX2	1808.0	-1479.0
CBX4	3352.0	-2144.0
CBX6	3215.0	-5159.0
CBX8	-2773.0	176.0
CCAR2	6598.0	-4714.0
CCNA2	4669.0	307.0
CCNE1	5096.0	360.0
CCNE2	2080.0	3324.0
CCS	6336.0	-6627.0
CDC16	6701.0	3924.0
CDC23	1748.0	710.0
CDC26	-3331.0	1610.0
CDC27	-4452.0	8433.0
CDK2	6186.0	-4240.0
CDK4	3355.0	-1971.0
CDK6	-5570.0	908.0
CDKN1A	7594.0	6372.0
CDKN1B	541.0	3790.0
CDKN2B	4291.0	-154.0
CDKN2C	6608.0	-3067.0
CDKN2D	6687.0	-4576.0
CEBPB	7403.0	754.0
CEBPG	-3135.0	6916.0
CHAC1	-5498.0	4031.0
CITED2	-1285.0	2778.0
COL4A6	-3205.0	1099.0
CREBBP	-6181.0	3954.0
CRYAB	6594.0	3169.0
CUL2	-6236.0	8506.0
CYBA	-4719.0	-4200.0
CYBB	-5520.0	5307.0
DCTN1	7218.0	-3098.0
DCTN2	2623.0	-2017.0
DCTN3	-715.0	689.0
DCTN4	-4133.0	7527.0
DCTN5	-4033.0	5094.0
DCTN6	4374.0	7565.0
DDIT3	-2070.0	-609.0
DEDD2	242.0	-4343.0
DEPDC5	7514.5	-6056.5
DNAJA1	-7303.0	6518.0
DNAJA2	-3327.0	8515.0
DNAJA4	-7004.0	6662.0
DNAJB1	-7114.0	1852.0
DNAJB6	-6088.0	7159.0
DNAJC2	-5076.0	7232.0
DNAJC7	-426.0	397.0
DYNC1H1	4822.0	2594.0
DYNC1I1	3045.0	-5230.0
DYNC1I2	-251.0	7398.0
DYNC1LI1	2249.0	7292.0
DYNC1LI2	-1436.0	1861.0
DYNLL1	-6952.0	7645.0
DYNLL2	4932.0	-5028.0
E2F1	4935.0	-488.0
E2F2	-2674.0	6447.0
E2F3	-3234.0	5297.0
EED	-1977.0	6430.0
EGLN1	-4261.5	-1804.5
EGLN2	1424.0	-6238.0
EGLN3	7904.0	4308.0
EHMT1	4203.0	1615.0
EHMT2	-610.0	-4085.0
EIF2AK1	-3590.0	6471.0
EIF2AK4	6877.0	-576.0
EIF2S1	-4830.0	8741.0
EIF2S2	-3307.0	8799.0
EIF2S3	-2819.5	4900.5
ELOB	6643.0	3269.0
ELOC	-3325.0	7837.0
EP300	-2449.0	1336.0
EP400	-2629.0	-5737.0
EPAS1	6886.0	8502.0
EPO	-1520.0	-1660.0
ERF	8190.0	-6273.0
ERO1A	3390.0	4892.0
ETS1	-599.0	8648.0
ETS2	2507.0	8278.0
EZH2	13.0	1789.0
FAU	6809.0	7710.0
FKBP4	-7096.0	-111.0
FKBP5	6201.0	5807.0
FNIP1	624.0	5543.0
FNIP2	7643.0	-6483.0
FOS	827.0	3751.0
FZR1	3996.0	-5000.0
GCN1	4616.0	-6124.0
GPX1	-1077.0	736.0
GPX3	7210.0	955.0
GPX6	7582.0	1018.0
GPX7	1995.0	2462.0
GPX8	-3495.0	7792.0
GRB10	-6904.0	2705.0
GSK3B	-5423.0	7184.0
GSR	-2480.0	4329.0
GSTP1	1683.0	2544.0
H1-0	7817.0	6665.0
H1-1	4222.0	7277.0
H1-2	7795.0	4082.0
H1-3	3925.0	-879.0
H1-4	7392.0	8249.0
H1-5	-1450.0	1228.0
H2AC20	7413.0	2470.0
H2AJ	-5416.0	2537.0
H2AZ1	-980.0	4206.0
H2AZ2	3558.0	1431.0
H2BC11	3900.0	-3127.0
H2BC14	1703.0	1613.0
H2BC5	3445.0	-761.0
H3-3A	-1695.0	7826.0
H3C15	7988.0	2080.0
HDAC6	7878.0	1757.0
HIF1A	7374.0	8562.0
HIF1AN	1768.0	-4927.0
HIF3A	5098.0	-246.0
HIGD1A	359.0	-3963.0
HIKESHI	-5969.0	1619.0
HIRA	-6015.0	-99.0
HMGA1	7803.0	-1488.0
HSF1	-1770.0	-3977.0
HSP90AA1	-7286.0	8742.0
HSP90AB1	-7306.0	5626.0
HSPA12A	-4571.0	1589.0
HSPA12B	4183.0	-2830.0
HSPA13	-7108.0	8023.0
HSPA14	3648.0	-1181.0
HSPA1A	-7272.5	7293.5
HSPA1B	-7272.5	7293.5
HSPA1L	-3778.0	-133.0
HSPA2	7012.0	5387.0
HSPA4	-6676.0	8292.0
HSPA4L	-7193.0	8500.0
HSPA5	-7309.0	7589.0
HSPA8	-7307.0	8180.0
HSPA9	-566.0	8181.0
HSPB8	-1109.0	6214.0
HSPH1	-7334.0	5252.0
ID1	3953.0	-1529.0
IGFBP7	-655.0	-4154.0
IL1A	-1142.0	1688.0
IMPACT	-2890.0	3450.0
ITFG2	826.0	-4600.0
JUN	581.0	5314.0
KAT5	5775.0	2767.0
KDM6B	7513.0	-6408.0
KPTN	3882.0	-3219.0
LAMTOR1	-81.0	-630.0
LAMTOR2	-2847.0	1280.0
LAMTOR3	2323.0	4870.0
LAMTOR4	-361.0	-1888.0
LAMTOR5	4258.0	4393.0
LIMD1	86.0	-5162.0
LMNB1	6899.0	-4624.0
MAP2K3	3494.0	-249.0
MAP2K4	2621.0	5572.0
MAP2K6	5640.0	-4115.0
MAP2K7	3505.0	-3383.0
MAP3K5	-5240.0	4568.0
MAP4K4	3979.0	7914.0
MAPK1	-3928.0	6920.0
MAPK10	-2089.0	-137.0
MAPK11	4349.0	2889.0
MAPK14	-6337.0	-1012.0
MAPK3	5390.0	5167.0
MAPK7	4710.0	-703.0
MAPK8	-3252.0	1695.0
MAPK9	2849.0	6624.0
MAPKAPK2	-2527.0	4587.0
MAPKAPK3	7267.0	-4297.0
MAPKAPK5	1373.0	5493.0
MDM2	5569.0	7967.0
MDM4	-2223.0	-5305.0
MINK1	-4877.0	-2450.0
MIOS	3016.0	4108.0
MLST8	-977.0	-1211.0
MOV10	-1088.0	-5618.0
MRE11	-3060.0	3329.0
MRPL18	-4156.0	1438.0
MTOR	-4145.0	-2344.0
NBN	-5298.0	8349.0
NCF1	3710.0	-659.0
NCF2	-1972.0	-3232.0
NCF4	-5987.0	5579.0
NDC1	6665.0	-1084.0
NFKB1	5449.0	4035.0
NOX4	7658.0	2944.0
NPRL2	-3789.0	2965.0
NPRL3	3415.0	-4551.0
NR3C1	-2732.0	2240.0
NR3C2	7008.0	-3900.0
NUDT2	1738.0	2579.0
NUP107	3423.0	7169.0
NUP133	2759.0	-4113.0
NUP153	-4638.0	7763.0
NUP155	6347.0	2192.0
NUP160	-5230.0	1753.0
NUP188	3880.0	-4145.0
NUP205	855.0	6303.0
NUP210	8193.0	-4172.0
NUP214	7802.0	-5326.0
NUP35	-4374.0	-921.0
NUP37	3596.0	1004.0
NUP42	4998.0	-596.0
NUP43	-2270.0	3764.0
NUP50	-4961.0	641.0
NUP54	-3355.0	6010.0
NUP58	2230.0	7116.0
NUP62	4963.0	-4765.0
NUP85	1103.0	-4750.0
NUP88	4817.0	4002.0
NUP93	5331.0	6196.0
NUP98	-2590.0	5122.0
P4HB	-6743.0	5398.0
PGR	-4247.0	5891.0
PHC1	-3375.0	-2631.0
PHC2	4373.0	-2023.0
PHC3	-3667.0	-4511.0
POM121	3732.5	-6552.5
POM121C	3732.5	-6552.5
POT1	-1630.0	-4746.0
PPP1R15A	7471.0	4761.0
PRDX1	-6422.0	8698.0
PRDX2	4337.0	4730.0
PRDX3	5471.0	4673.0
PRDX5	-4102.0	2801.0
PRDX6	-3287.0	3877.0
PSMA1	-6705.0	7838.0
PSMA2	-5464.5	6058.5
PSMA3	-3145.0	7801.0
PSMA4	-6074.0	4688.0
PSMA5	-6660.0	4497.0
PSMA6	-1954.0	8445.0
PSMA7	1612.0	7052.0
PSMA8	649.0	-4004.0
PSMB1	-5281.0	5936.0
PSMB10	3752.0	-908.0
PSMB11	1977.0	-5501.0
PSMB2	1472.0	-4144.0
PSMB3	-3388.0	5539.0
PSMB4	-4941.0	-5852.0
PSMB5	-1638.0	-2409.0
PSMB6	1806.0	-1845.0
PSMB7	-4628.0	-657.0
PSMB8	1080.0	-3793.0
PSMB9	5987.0	-4708.0
PSMC1	-1312.0	4327.0
PSMC2	-6765.0	4648.0
PSMC3	-4285.0	3386.0
PSMC4	-6423.0	7920.0
PSMC5	-4831.0	1120.0
PSMC6	-6851.0	8666.0
PSMD1	-6497.0	8619.0
PSMD10	-1613.0	2576.0
PSMD11	-6873.0	5201.0
PSMD12	-6149.0	8628.0
PSMD13	1898.0	5044.0
PSMD14	-6080.0	8262.0
PSMD2	-6702.0	-3836.0
PSMD3	-2532.0	-3242.0
PSMD4	-5648.0	4994.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
PSMD7	-6943.0	7625.0
PSMD8	1978.0	7546.0
PSMD9	7707.5	-894.5
PSME1	2907.0	5905.0
PSME2	1270.0	-4595.0
PSME3	752.0	7366.0
PSME4	-6830.0	8511.0
PSMF1	5087.0	4771.0
PTGES3	-7067.0	8733.0
RAD50	6606.5	676.5
RAE1	3041.0	-1934.0
RANBP2	-4575.0	8132.0
RB1	7982.0	7013.0
RBBP4	-6148.0	5835.0
RBBP7	2154.0	6750.0
RBX1	-391.0	3201.0
RELA	2579.0	-2368.0
RHEB	-3280.0	-1691.0
RING1	2092.0	-5540.0
RLN1	2347.5	469.5
RNF2	-3811.0	8651.0
RPA1	4920.0	5750.0
RPA2	6082.0	4722.0
RPA3	3029.0	1440.0
RPL11	5748.0	1403.0
RPL12	6107.0	-5604.0
RPL13	5686.0	-3760.0
RPL14	5110.0	-1875.0
RPL18	2523.0	-625.0
RPL18A	4545.0	-3218.0
RPL19	4654.0	6782.0
RPL21	-1686.0	8463.0
RPL22	2365.0	459.0
RPL22L1	-5123.0	-6294.0
RPL23	-205.0	4253.0
RPL24	-409.0	6813.0
RPL26	3650.0	8722.0
RPL28	6714.0	4753.0
RPL29	2613.0	4628.0
RPL3	5378.0	1155.0
RPL30	4372.0	3664.0
RPL31	6732.0	-1507.0
RPL32	2989.0	8728.0
RPL34	661.0	7140.0
RPL35	5949.0	8834.0
RPL35A	-1509.0	6565.0
RPL36	7543.0	-2424.0
RPL36A	-5983.0	4837.0
RPL36AL	1793.0	-2074.0
RPL37	2109.0	-667.0
RPL38	5601.0	5675.0
RPL3L	-5986.0	4937.0
RPL4	2582.0	8471.0
RPL6	572.0	7594.0
RPL7	-5186.0	8598.0
RPL8	3526.0	820.0
RPLP2	3550.0	3555.0
RPS13	7174.0	315.0
RPS14	4070.0	4443.0
RPS15	7253.0	6174.0
RPS16	6244.0	1119.0
RPS17	5667.0	7685.0
RPS18	4253.0	-526.0
RPS19	6565.0	-1215.0
RPS19BP1	-6099.0	5732.0
RPS2	7322.0	4216.0
RPS21	7111.0	-6494.0
RPS25	4261.0	8455.0
RPS27A	-133.0	-1807.0
RPS28	7208.0	-396.0
RPS3	2340.0	4381.0
RPS3A	-3115.0	8824.0
RPS4X	2522.0	7391.0
RPS5	3848.0	7515.0
RPS6	-1700.0	8603.0
RPS6KA1	7703.0	4452.0
RPS6KA2	7237.0	-2956.0
RPS6KA3	-6111.0	8270.0
RPS8	3874.0	7646.0
RPS9	-1719.0	-2555.0
RPTOR	1708.0	-6268.0
RRAGA	-3310.0	5815.0
RRAGB	1312.0	-1809.0
RRAGC	-2715.0	5320.0
RRAGD	7798.0	3815.0
SCMH1	2113.0	-1086.0
SEC13	-1432.0	3604.0
SEH1L	2204.0	6910.0
SERPINH1	-7218.0	4296.0
SESN1	6129.0	5296.0
SESN2	-4377.0	1285.0
SH3BP4	7669.0	3702.0
SIRT1	165.0	6375.0
SLC38A9	-1355.0	-5207.0
SOD1	-7054.0	2583.0
SOD2	-1635.0	4013.0
SOD3	-1080.0	-2376.0
SP1	571.0	4734.0
ST13	-7144.0	7998.0
STAT3	8126.0	4982.0
STIP1	-7236.0	7449.0
SUZ12	-1028.0	8662.0
SZT2	-3750.0	-6450.0
TCIRG1	-5363.0	-3931.0
TERF1	-6043.0	4260.0
TERF2	5515.0	5270.0
TERF2IP	-2169.0	2046.0
TFDP1	-6289.0	4476.0
TFDP2	7449.0	3780.0
TINF2	2114.0	2374.0
TNFRSF21	7819.0	3310.0
TNIK	2227.0	4457.0
TNRC6A	4450.0	-2617.0
TNRC6B	613.0	-4375.0
TNRC6C	2604.0	-4658.0
TP53	2557.0	-3561.0
TPR	-4239.0	8611.0
TRIB3	3661.0	-614.0
TXN	-5397.0	-2909.0
TXN2	-2656.0	1641.0
TXNRD1	-3425.0	4896.0
TXNRD2	-2117.0	-5805.0
UBA52	7488.0	-4269.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
UBE2C	733.0	-1864.0
UBE2D1	5638.0	3025.0
UBE2D2	-935.0	6690.0
UBE2D3	-5084.0	8317.0
UBE2E1	-6831.0	8405.0
UBE2S	4549.0	-1742.0
UBN1	-3031.0	-5794.0
VCP	-7069.0	5449.0
VEGFA	-4619.0	-5156.0
WDR24	-1198.0	568.0
WDR59	-2025.0	-4156.0
WTIP	-4878.0	-1899.0
YWHAE	-2079.0	7315.0

---

---

Apoptosis

Apoptosis

metric	value
setSize	164
pMANOVA	4.27e-09
p.adjustMANOVA	1.57e-07
s.dist	0.292
s.diabetes	-0.0827
s.mitoG	0.28
p.diabetes	0.068
p.mitoG	6.17e-10

Top 20 genes

Gene	diabetes	mitoG
PSMC6	-6851	8666
UBB	-7104	8341
PSME4	-6830	8511
PSMD1	-6497	8619
DYNLL1	-6952	7645
PSMD12	-6149	8628
PSMD7	-6943	7625
PSMA1	-6705	7838
UBC	-6013	8514
PSMC4	-6423	7920
PSMD14	-6080	8262
KPNA1	-5632	8815
YWHAH	-6051	7949
YWHAZ	-5614	8512
CASP8	-5258	8694
BCAP31	-6657	6845
PSMD5	-6156	7150
DNM1L	-4825	8774
YWHAB	-4723	8579
PSMD6	-6385	6157

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
ACIN1	1868.0	-3396.0
ADD1	-5137.0	969.0
AKT1	4859.0	7244.0
AKT2	-4939.0	3281.0
AKT3	-375.0	7862.0
APAF1	-1681.0	4531.0
APC	4716.0	8376.0
APIP	1979.0	6328.0
APPL1	940.0	7089.0
ARHGAP10	-6608.0	-2003.0
AVEN	-2870.0	-1960.0
BAD	-2216.0	-4664.0
BAK1	7177.0	3473.0
BAX	6141.0	-6683.0
BCAP31	-6657.0	6845.0
BCL2	-1449.0	-2113.0
BCL2L1	1254.0	3623.0
BCL2L11	7084.0	668.0
BID	-6112.0	-270.0
BIRC2	-4230.0	3665.0
BMF	-245.0	3162.0
BMX	5552.0	4493.0
C1QBP	4206.0	1754.0
CASP3	4881.0	3606.0
CASP6	2935.0	3986.0
CASP7	6240.0	526.0
CASP8	-5258.0	8694.0
CASP9	2469.0	-5751.0
CD14	4081.0	6994.0
CDH1	-1038.0	5837.0
CFLAR	-4054.0	2224.0
CLSPN	3534.0	-3857.0
CTNNB1	-6022.0	2664.0
DAPK1	-3680.0	770.0
DAPK2	-2126.0	4028.0
DAPK3	3.0	-5598.0
DBNL	3890.0	-1155.0
DFFA	4899.0	-803.0
DFFB	6044.0	-6041.0
DIABLO	-3178.0	5083.0
DNM1L	-4825.0	8774.0
DSG2	7918.0	5394.0
DSP	7655.0	6828.0
DYNLL1	-6952.0	7645.0
DYNLL2	4932.0	-5028.0
E2F1	4935.0	-488.0
FADD	6301.0	-5424.0
FAS	3093.0	7580.0
FASLG	834.0	4880.0
FNTA	-593.0	5888.0
GAS2	-7224.0	5159.0
GSN	7535.0	7997.0
GZMB	270.0	-2421.0
H1-0	7817.0	6665.0
H1-1	4222.0	7277.0
H1-2	7795.0	4082.0
H1-3	3925.0	-879.0
H1-4	7392.0	8249.0
H1-5	-1450.0	1228.0
HMGB1	2876.0	8283.0
HMGB2	6857.0	1304.0
KPNA1	-5632.0	8815.0
KPNB1	-1668.0	5829.0
LMNA	5092.0	-3667.0
LMNB1	6899.0	-4624.0
LY96	-4879.0	364.0
MAGED1	-6546.0	5010.0
MAPK1	-3928.0	6920.0
MAPK3	5390.0	5167.0
MAPK8	-3252.0	1695.0
MAPT	-6403.0	3350.0
NMT1	-6059.0	6229.0
OCLN	6047.0	-451.0
OMA1	-4909.0	-736.0
OPA1	1629.0	7798.0
PAK2	-4906.0	6708.0
PLEC	8057.0	180.0
PMAIP1	2215.0	5575.0
PPP1R13B	3221.0	7424.0
PPP3CC	5563.0	4840.0
PPP3R1	2835.5	8199.5
PRKCD	365.0	1901.0
PRKCQ	-2002.0	-3514.0
PSMA1	-6705.0	7838.0
PSMA2	-5464.5	6058.5
PSMA3	-3145.0	7801.0
PSMA4	-6074.0	4688.0
PSMA5	-6660.0	4497.0
PSMA6	-1954.0	8445.0
PSMA7	1612.0	7052.0
PSMA8	649.0	-4004.0
PSMB1	-5281.0	5936.0
PSMB10	3752.0	-908.0
PSMB11	1977.0	-5501.0
PSMB2	1472.0	-4144.0
PSMB3	-3388.0	5539.0
PSMB4	-4941.0	-5852.0
PSMB5	-1638.0	-2409.0
PSMB6	1806.0	-1845.0
PSMB7	-4628.0	-657.0
PSMB8	1080.0	-3793.0
PSMB9	5987.0	-4708.0
PSMC1	-1312.0	4327.0
PSMC2	-6765.0	4648.0
PSMC3	-4285.0	3386.0
PSMC4	-6423.0	7920.0
PSMC5	-4831.0	1120.0
PSMC6	-6851.0	8666.0
PSMD1	-6497.0	8619.0
PSMD10	-1613.0	2576.0
PSMD11	-6873.0	5201.0
PSMD12	-6149.0	8628.0
PSMD13	1898.0	5044.0
PSMD14	-6080.0	8262.0
PSMD2	-6702.0	-3836.0
PSMD3	-2532.0	-3242.0
PSMD4	-5648.0	4994.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
PSMD7	-6943.0	7625.0
PSMD8	1978.0	7546.0
PSMD9	7707.5	-894.5
PSME1	2907.0	5905.0
PSME2	1270.0	-4595.0
PSME3	752.0	7366.0
PSME4	-6830.0	8511.0
PSMF1	5087.0	4771.0
PTK2	2264.0	6997.0
RIPK1	-2977.0	5088.0
ROCK1	-2765.0	8654.0
RPS27A	-133.0	-1807.0
SATB1	-1732.0	4168.0
SFN	3916.0	5704.0
SPTAN1	7051.0	7359.0
STAT3	8126.0	4982.0
STK24	4748.0	-214.0
STK26	-1443.0	7201.0
TFDP1	-6289.0	4476.0
TFDP2	7449.0	3780.0
TICAM1	-1539.0	-3874.0
TJP1	4021.0	8531.0
TJP2	-3964.5	6046.5
TLR4	-4128.0	8470.0
TNFSF10	-6011.0	987.0
TP53	2557.0	-3561.0
TP53BP2	6638.0	5316.0
TP63	-3604.0	1254.0
TP73	2068.0	84.0
TRADD	-1318.0	-2687.0
TRAF2	3405.0	-3806.0
UACA	5605.0	7217.0
UBA52	7488.0	-4269.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
UNC5A	-1287.0	-1741.0
UNC5B	6777.0	5303.0
VIM	5500.0	7940.0
XIAP	-4862.0	7852.0
YWHAB	-4723.0	8579.0
YWHAE	-2079.0	7315.0
YWHAG	-5348.0	1700.0
YWHAH	-6051.0	7949.0
YWHAQ	3046.0	8675.0
YWHAZ	-5614.0	8512.0

---

---

Binding and Uptake of Ligands by Scavenger Receptors

Binding and Uptake of Ligands by Scavenger Receptors

metric	value
setSize	54
pMANOVA	4.4e-09
p.adjustMANOVA	1.58e-07
s.dist	0.486
s.diabetes	-0.0427
s.mitoG	0.484
p.diabetes	0.588
p.mitoG	7.54e-10

Top 20 genes

Gene	diabetes	mitoG
IGHV1-69	-7353.5	8845.5
IGKV4-1	-7301.0	8840.0
HSP90AA1	-7286.0	8742.0
HSP90B1	-7279.0	8368.0
IGKV5-2	-5895.0	8671.0
CD36	-7328.0	6006.0
CALR	-7105.0	5809.0
HSPH1	-7334.0	5252.0
IGHA1	-5036.5	7384.5
IGHA2	-5036.5	7384.5
HYOU1	-7255.0	4009.0
IGKC	-2925.0	7318.0
CD163	-2470.0	7418.0
APOL1	-5660.5	2701.5
COL4A1	-1913.0	7738.0
JCHAIN	-1963.0	6913.0
IGLV4-60	-3537.5	3617.5
IGLV4-69	-3537.5	3617.5
HP	-1369.5	6104.5
HPR	-1369.5	6104.5

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
ALB	6253.0	-380.0
AMBP	4518.0	-3879.0
APOA1	3682.0	-305.0
APOB	7604.0	5782.0
APOE	5835.0	342.0
APOL1	-5660.5	2701.5
CALR	-7105.0	5809.0
CD163	-2470.0	7418.0
CD36	-7328.0	6006.0
COL1A1	112.0	2092.0
COL1A2	416.0	5053.0
COL3A1	-2073.0	3836.0
COL4A1	-1913.0	7738.0
COL4A2	5885.0	8130.0
COLEC11	631.0	3003.0
COLEC12	190.0	8600.0
FTL	-6693.0	-6771.0
HBA1	5772.5	8630.5
HP	-1369.5	6104.5
HPR	-1369.5	6104.5
HPX	2769.0	2190.0
HSP90AA1	-7286.0	8742.0
HSP90B1	-7279.0	8368.0
HSPH1	-7334.0	5252.0
HYOU1	-7255.0	4009.0
IGHA1	-5036.5	7384.5
IGHA2	-5036.5	7384.5
IGHV1-69	-7353.5	8845.5
IGHV2-5	4395.0	4965.0
IGHV2-70	4395.0	4965.0
IGHV7-81	517.5	7570.5
IGKC	-2925.0	7318.0
IGKV1-12	2052.5	4944.5
IGKV1-17	2052.5	4944.5
IGKV1-39	2052.5	4944.5
IGKV1D-12	2052.5	4944.5
IGKV1D-39	2052.5	4944.5
IGKV2-30	101.5	8396.5
IGKV2D-30	101.5	8396.5
IGKV4-1	-7301.0	8840.0
IGKV5-2	-5895.0	8671.0
IGLV4-60	-3537.5	3617.5
IGLV4-69	-3537.5	3617.5
JCHAIN	-1963.0	6913.0
LRP1	7344.0	8465.0
MASP1	7705.0	8599.0
MSR1	336.0	3428.0
SCARA5	5837.0	696.0
SCARB1	2415.0	4827.0
SCARF1	4977.0	-975.0
SPARC	6297.0	8700.0
SSC5D	4955.0	-2682.0
STAB1	8142.0	4360.0
STAB2	3055.0	-2320.0

---

---

FCERI mediated NF-kB activation

FCERI mediated NF-kB activation

metric	value
setSize	91
pMANOVA	4.57e-09
p.adjustMANOVA	1.6e-07
s.dist	0.413
s.diabetes	-0.258
s.mitoG	0.322
p.diabetes	2.16e-05
p.mitoG	1.1e-07

Top 20 genes

Gene	diabetes	mitoG
IGHV1-69	-7353.5	8845.5
IGKV4-1	-7301.0	8840.0
PSMC6	-6851.0	8666.0
UBB	-7104.0	8341.0
PSME4	-6830.0	8511.0
SKP1	-6803.0	8394.0
PSMD1	-6497.0	8619.0
PSMD12	-6149.0	8628.0
PSMD7	-6943.0	7625.0
PSMA1	-6705.0	7838.0
TAB2	-7040.0	7307.0
UBC	-6013.0	8514.0
IGKV5-2	-5895.0	8671.0
PSMC4	-6423.0	7920.0
PSMD14	-6080.0	8262.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
LYN	-4685.0	8216.0
PSMD11	-6873.0	5201.0
PSMA2	-5464.5	6058.5

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
BCL10	-3598.0	5942.0
BTRC	3218.0	-5334.0
CARD11	-3020.0	3028.0
CDC34	-806.0	2346.0
CHUK	-3701.0	8556.0
CUL1	-2997.0	6875.0
FBXW11	-3788.0	3125.0
IGHV1-69	-7353.5	8845.5
IGHV2-5	4395.0	4965.0
IGHV2-70	4395.0	4965.0
IGHV7-81	517.5	7570.5
IGKC	-2925.0	7318.0
IGKV1-12	2052.5	4944.5
IGKV1-17	2052.5	4944.5
IGKV1-39	2052.5	4944.5
IGKV1D-12	2052.5	4944.5
IGKV1D-39	2052.5	4944.5
IGKV2-30	101.5	8396.5
IGKV2D-30	101.5	8396.5
IGKV4-1	-7301.0	8840.0
IGKV5-2	-5895.0	8671.0
IGLV4-60	-3537.5	3617.5
IGLV4-69	-3537.5	3617.5
IKBKB	-1785.0	-5829.0
IKBKG	3700.0	-677.0
LYN	-4685.0	8216.0
MALT1	-2981.0	1806.0
MAP3K7	1594.0	7480.0
NFKB1	5449.0	4035.0
NFKBIA	1631.0	4830.0
PDPK1	-4074.0	1936.0
PRKCQ	-2002.0	-3514.0
PSMA1	-6705.0	7838.0
PSMA2	-5464.5	6058.5
PSMA3	-3145.0	7801.0
PSMA4	-6074.0	4688.0
PSMA5	-6660.0	4497.0
PSMA6	-1954.0	8445.0
PSMA7	1612.0	7052.0
PSMA8	649.0	-4004.0
PSMB1	-5281.0	5936.0
PSMB10	3752.0	-908.0
PSMB11	1977.0	-5501.0
PSMB2	1472.0	-4144.0
PSMB3	-3388.0	5539.0
PSMB4	-4941.0	-5852.0
PSMB5	-1638.0	-2409.0
PSMB6	1806.0	-1845.0
PSMB7	-4628.0	-657.0
PSMB8	1080.0	-3793.0
PSMB9	5987.0	-4708.0
PSMC1	-1312.0	4327.0
PSMC2	-6765.0	4648.0
PSMC3	-4285.0	3386.0
PSMC4	-6423.0	7920.0
PSMC5	-4831.0	1120.0
PSMC6	-6851.0	8666.0
PSMD1	-6497.0	8619.0
PSMD10	-1613.0	2576.0
PSMD11	-6873.0	5201.0
PSMD12	-6149.0	8628.0
PSMD13	1898.0	5044.0
PSMD14	-6080.0	8262.0
PSMD2	-6702.0	-3836.0
PSMD3	-2532.0	-3242.0
PSMD4	-5648.0	4994.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
PSMD7	-6943.0	7625.0
PSMD8	1978.0	7546.0
PSMD9	7707.5	-894.5
PSME1	2907.0	5905.0
PSME2	1270.0	-4595.0
PSME3	752.0	7366.0
PSME4	-6830.0	8511.0
PSMF1	5087.0	4771.0
RASGRP1	-370.0	-2734.0
RASGRP2	-326.0	-409.0
RASGRP4	-3063.0	1538.0
RELA	2579.0	-2368.0
RPS27A	-133.0	-1807.0
SKP1	-6803.0	8394.0
TAB1	7839.0	-5339.0
TAB2	-7040.0	7307.0
TAB3	3966.0	5424.0
TRAF6	1082.0	6626.0
UBA52	7488.0	-4269.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
UBE2D1	5638.0	3025.0
UBE2D2	-935.0	6690.0

---

---

rRNA processing in the nucleus and cytosol

rRNA processing in the nucleus and cytosol

metric	value
setSize	154
pMANOVA	7.37e-09
p.adjustMANOVA	2.52e-07
s.dist	0.272
s.diabetes	0.0375
s.mitoG	0.269
p.diabetes	0.423
p.mitoG	8.49e-09

Top 20 genes

Gene	diabetes	mitoG
NCL	6850.0	8762.0
RPL35	5949.0	8834.0
FAU	6809.0	7710.0
UTP20	8200.0	5794.0
XRN2	7433.0	6374.0
RPS15	7253.0	6174.0
RPS17	5667.0	7685.0
NIP7	5420.0	6991.0
RPS25	4261.0	8455.0
EXOSC9	4661.0	7068.0
RRP1	5293.0	6186.0
UTP15	4856.0	6673.0
RPL28	6714.0	4753.0
RPL26	3650.0	8722.0
RPL38	5601.0	5675.0
RPL19	4654.0	6782.0
RPS2	7322.0	4216.0
RPS8	3874.0	7646.0
RPS5	3848.0	7515.0
CSNK1E	5383.5	5055.5

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
BMS1	-5831.0	3306.0
BOP1	-3585.0	976.0
BYSL	-4542.0	5843.0
C1D	-5321.0	8041.0
CSNK1D	-1602.0	2506.0
CSNK1E	5383.5	5055.5
DCAF13	-6109.0	5418.0
DDX21	-5116.0	8276.0
DDX47	3030.0	755.0
DDX49	4404.0	-1145.0
DDX52	-4060.0	7194.0
DHX37	-533.0	-1936.0
DIMT1	2968.0	-3709.0
DIS3	-6175.0	6931.0
DKC1	-5095.0	7179.0
EBNA1BP2	-2177.0	6468.0
EMG1	-6093.0	-1167.0
ERI1	-5053.0	4453.0
EXOSC1	-2448.0	7613.0
EXOSC10	1760.0	8346.0
EXOSC2	3957.0	3800.0
EXOSC3	-1469.0	-3935.0
EXOSC4	-3182.0	-4923.0
EXOSC5	4223.0	-3378.0
EXOSC7	6973.0	-5606.0
EXOSC8	6788.0	616.0
EXOSC9	4661.0	7068.0
FAU	6809.0	7710.0
FBL	6041.0	-6202.0
FTSJ3	364.0	-330.0
GAR1	642.0	-352.0
GNL3	-4340.0	6867.0
HEATR1	-6514.0	7682.0
IMP3	3952.0	-6093.0
IMP4	186.0	5570.0
ISG20L2	-4479.0	3406.0
KRR1	-4385.0	7088.0
LAS1L	1684.0	1715.0
LTV1	-279.5	6894.5
MPHOSPH10	-5904.0	8696.0
MPHOSPH6	-3203.0	7923.0
MTREX	-6973.0	5247.0
NAT10	2042.0	-2361.0
NCL	6850.0	8762.0
NHP2	-5332.0	6281.0
NIP7	5420.0	6991.0
NOB1	-3003.0	2527.0
NOC4L	5961.0	1908.0
NOL11	-4046.0	6580.0
NOL12	-3477.5	6109.5
NOL6	7943.0	-3108.0
NOL9	-1832.0	-148.0
NOP10	2308.0	5890.0
NOP14	-2312.0	6526.0
NOP56	-875.0	1129.0
NOP58	-4438.0	5964.0
PDCD11	-4002.0	-3015.0
PELP1	1681.0	-4851.0
PES1	2890.0	6091.0
PNO1	-5524.0	8385.0
PWP2	4987.5	-4444.5
RBM28	-5098.0	2336.0
RCL1	5218.0	4620.0
RIOK1	-1297.0	7015.0
RIOK2	-670.0	7303.0
RIOK3	-3202.0	8097.0
RPL11	5748.0	1403.0
RPL12	6107.0	-5604.0
RPL13	5686.0	-3760.0
RPL14	5110.0	-1875.0
RPL18	2523.0	-625.0
RPL18A	4545.0	-3218.0
RPL19	4654.0	6782.0
RPL21	-1686.0	8463.0
RPL22	2365.0	459.0
RPL22L1	-5123.0	-6294.0
RPL23	-205.0	4253.0
RPL24	-409.0	6813.0
RPL26	3650.0	8722.0
RPL28	6714.0	4753.0
RPL29	2613.0	4628.0
RPL3	5378.0	1155.0
RPL30	4372.0	3664.0
RPL31	6732.0	-1507.0
RPL32	2989.0	8728.0
RPL34	661.0	7140.0
RPL35	5949.0	8834.0
RPL35A	-1509.0	6565.0
RPL36	7543.0	-2424.0
RPL36A	-5983.0	4837.0
RPL36AL	1793.0	-2074.0
RPL37	2109.0	-667.0
RPL38	5601.0	5675.0
RPL3L	-5986.0	4937.0
RPL4	2582.0	8471.0
RPL6	572.0	7594.0
RPL7	-5186.0	8598.0
RPL8	3526.0	820.0
RPLP2	3550.0	3555.0
RPP14	-1705.0	2028.0
RPP21	1368.0	437.0
RPP25	5432.0	3890.0
RPP30	-4567.0	4289.0
RPP38	-3284.0	7004.0
RPP40	-5546.0	2654.0
RPS13	7174.0	315.0
RPS14	4070.0	4443.0
RPS15	7253.0	6174.0
RPS16	6244.0	1119.0
RPS17	5667.0	7685.0
RPS18	4253.0	-526.0
RPS19	6565.0	-1215.0
RPS2	7322.0	4216.0
RPS21	7111.0	-6494.0
RPS25	4261.0	8455.0
RPS27A	-133.0	-1807.0
RPS28	7208.0	-396.0
RPS3	2340.0	4381.0
RPS3A	-3115.0	8824.0
RPS4X	2522.0	7391.0
RPS5	3848.0	7515.0
RPS6	-1700.0	8603.0
RPS8	3874.0	7646.0
RPS9	-1719.0	-2555.0
RRP1	5293.0	6186.0
RRP36	3453.0	244.0
RRP7A	-1466.0	3721.0
RRP9	2614.0	851.0
SENP3	-2124.5	3519.5
SNU13	-4083.0	7577.0
TBL3	5799.0	-3253.0
TEX10	5529.0	1840.0
THUMPD1	-2693.0	6882.0
TRMT112	-6614.0	-1009.0
TSR1	-4634.0	2623.0
TSR3	4228.0	-5856.0
UBA52	7488.0	-4269.0
UTP11	-3324.0	3075.0
UTP14A	-755.5	3859.5
UTP14C	-755.5	3859.5
UTP15	4856.0	6673.0
UTP18	1908.0	6014.0
UTP20	8200.0	5794.0
UTP3	-2706.0	6844.0
UTP4	-4384.0	4038.0
UTP6	-3727.0	5591.0
WDR12	-3943.0	1434.0
WDR18	-5000.0	-3150.0
WDR3	-6076.0	2575.0
WDR36	5285.0	-1626.0
WDR43	2708.0	8166.0
WDR46	5078.0	-4710.0
WDR75	-3646.0	8219.0
XRN2	7433.0	6374.0

---

---

Influenza Viral RNA Transcription and Replication

Influenza Viral RNA Transcription and Replication

metric	value
setSize	103
pMANOVA	8.5e-09
p.adjustMANOVA	2.84e-07
s.dist	0.31
s.diabetes	0.248
s.mitoG	0.185
p.diabetes	1.35e-05
p.mitoG	0.00117

Top 20 genes

Gene	diabetes	mitoG
RPL35	5949	8834
FAU	6809	7710
RPS15	7253	6174
RPS17	5667	7685
POLR2I	5890	6864
RPS25	4261	8455
NUP93	5331	6196
RPL28	6714	4753
RPL26	3650	8722
RPL38	5601	5675
RPL19	4654	6782
RPS2	7322	4216
RPS8	3874	7646
RPS5	3848	7515
RPL32	2989	8728
NUP107	3423	7169
IPO5	7411	3285
RPL4	2582	8471
POLR2C	2928	6859
NUP88	4817	4002

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
AAAS	5561.0	-2261.0
DNAJC3	-7149.0	8179.0
FAU	6809.0	7710.0
GRSF1	4054.0	-1610.0
GTF2F1	373.0	6337.0
GTF2F2	-1458.0	7912.0
HSP90AA1	-7286.0	8742.0
IPO5	7411.0	3285.0
NDC1	6665.0	-1084.0
NUP107	3423.0	7169.0
NUP133	2759.0	-4113.0
NUP153	-4638.0	7763.0
NUP155	6347.0	2192.0
NUP160	-5230.0	1753.0
NUP188	3880.0	-4145.0
NUP205	855.0	6303.0
NUP210	8193.0	-4172.0
NUP214	7802.0	-5326.0
NUP35	-4374.0	-921.0
NUP37	3596.0	1004.0
NUP42	4998.0	-596.0
NUP43	-2270.0	3764.0
NUP50	-4961.0	641.0
NUP54	-3355.0	6010.0
NUP58	2230.0	7116.0
NUP62	4963.0	-4765.0
NUP85	1103.0	-4750.0
NUP88	4817.0	4002.0
NUP93	5331.0	6196.0
NUP98	-2590.0	5122.0
PARP1	134.0	473.0
POLR2A	4937.0	-1941.0
POLR2B	-675.0	5037.0
POLR2C	2928.0	6859.0
POLR2D	-2762.0	6076.0
POLR2E	7128.0	-3504.0
POLR2F	6184.0	-3058.0
POLR2G	3306.0	-3566.0
POLR2H	4359.0	-4161.0
POLR2I	5890.0	6864.0
POLR2J	1742.0	3424.0
POLR2K	1098.0	7632.0
POLR2L	3697.0	-3808.0
POM121	3732.5	-6552.5
POM121C	3732.5	-6552.5
RAE1	3041.0	-1934.0
RANBP2	-4575.0	8132.0
RPL11	5748.0	1403.0
RPL12	6107.0	-5604.0
RPL13	5686.0	-3760.0
RPL14	5110.0	-1875.0
RPL18	2523.0	-625.0
RPL18A	4545.0	-3218.0
RPL19	4654.0	6782.0
RPL21	-1686.0	8463.0
RPL22	2365.0	459.0
RPL22L1	-5123.0	-6294.0
RPL23	-205.0	4253.0
RPL24	-409.0	6813.0
RPL26	3650.0	8722.0
RPL28	6714.0	4753.0
RPL29	2613.0	4628.0
RPL3	5378.0	1155.0
RPL30	4372.0	3664.0
RPL31	6732.0	-1507.0
RPL32	2989.0	8728.0
RPL34	661.0	7140.0
RPL35	5949.0	8834.0
RPL35A	-1509.0	6565.0
RPL36	7543.0	-2424.0
RPL36A	-5983.0	4837.0
RPL36AL	1793.0	-2074.0
RPL37	2109.0	-667.0
RPL38	5601.0	5675.0
RPL3L	-5986.0	4937.0
RPL4	2582.0	8471.0
RPL6	572.0	7594.0
RPL7	-5186.0	8598.0
RPL8	3526.0	820.0
RPLP2	3550.0	3555.0
RPS13	7174.0	315.0
RPS14	4070.0	4443.0
RPS15	7253.0	6174.0
RPS16	6244.0	1119.0
RPS17	5667.0	7685.0
RPS18	4253.0	-526.0
RPS19	6565.0	-1215.0
RPS2	7322.0	4216.0
RPS21	7111.0	-6494.0
RPS25	4261.0	8455.0
RPS27A	-133.0	-1807.0
RPS28	7208.0	-396.0
RPS3	2340.0	4381.0
RPS3A	-3115.0	8824.0
RPS4X	2522.0	7391.0
RPS5	3848.0	7515.0
RPS6	-1700.0	8603.0
RPS8	3874.0	7646.0
RPS9	-1719.0	-2555.0
SEC13	-1432.0	3604.0
SEH1L	2204.0	6910.0
TPR	-4239.0	8611.0
UBA52	7488.0	-4269.0

---

---

Diseases of signal transduction by growth factor receptors and second messengers

Diseases of signal transduction by growth factor receptors and second messengers

metric	value
setSize	362
pMANOVA	9.24e-09
p.adjustMANOVA	3.01e-07
s.dist	0.201
s.diabetes	-0.0965
s.mitoG	0.177
p.diabetes	0.00167
p.mitoG	8.66e-09

Top 20 genes

Gene	diabetes	mitoG
HSP90AA1	-7286.0	8742.0
RAP1A	-6787.0	8805.0
PSMC6	-6851.0	8666.0
UBB	-7104.0	8341.0
PSME4	-6830.0	8511.0
SKP1	-6803.0	8394.0
PSMD1	-6497.0	8619.0
SEL1L	-7264.0	7670.0
FGFR1OP2	-6599.0	8434.0
HDAC2	-6396.0	8620.0
SPRED1	-6354.0	8554.0
TBL1X	-7106.5	7510.5
PSMD12	-6149.0	8628.0
PSMD7	-6943.0	7625.0
PSMA1	-6705.0	7838.0
ADAM10	-6444.0	8149.0
UBC	-6013.0	8514.0
QKI	-6268.0	8165.0
PSMC4	-6423.0	7920.0
SOS1	-6566.0	7698.0

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
ADAM10	-6444.0	8149.0
ADAM17	-5121.0	3275.0
AGGF1	-5856.5	4390.5
AGK	2444.0	4916.0
AGTRAP	-4487.0	-6054.0
AKAP9	-4986.0	7264.0
AKT1	4859.0	7244.0
AKT1S1	3062.0	-5699.0
AKT2	-4939.0	3281.0
AKT3	-375.0	7862.0
AMER1	1557.0	4171.0
AP3B1	3159.0	1998.0
APBB1IP	-5251.0	-2322.0
APC	4716.0	8376.0
APH1A	5635.0	-6359.0
APH1B	7972.0	373.0
ARAF	4130.0	-5879.0
ARRB1	-6250.0	3030.0
ARRB2	-3644.0	681.0
ATG7	7859.0	-906.0
AXIN1	2211.0	-3480.0
BAD	-2216.0	-4664.0
BAG4	7654.0	5147.0
BCL2L11	7084.0	668.0
BCR	-1554.0	-5381.0
BIN2	-3519.0	1037.0
BRAF	-6284.0	4955.0
BRAP	-3859.0	735.0
BTC	7701.0	1951.0
CALM1	-4401.0	8702.0
CAMK2A	-2272.0	4664.0
CAMK2B	2551.0	5253.0
CAMK2G	5581.0	-3540.0
CASP9	2469.0	-5751.0
CBL	-6462.0	4306.0
CCNC	-3288.0	7605.0
CD19	-2666.0	-3652.0
CD28	-4408.0	5134.0
CD80	-3453.0	3286.0
CD86	-2679.0	5554.0
CDC37	-682.0	-4414.0
CDK8	5984.0	-5196.0
CDKN1A	7594.0	6372.0
CDKN1B	541.0	3790.0
CEP43	1089.0	2218.0
CHUK	-3701.0	8556.0
CLCN6	-5634.0	-5403.0
CNKSR1	7454.0	1081.0
CNKSR2	3628.0	-207.0
CNTRL	6882.0	1622.0
CPSF6	-4618.0	2233.0
CREB1	-6809.0	5166.0
CREBBP	-6181.0	3954.0
CSK	-5802.0	-2193.0
CSNK1A1	3705.0	5154.0
CTBP1	2741.0	-5332.0
CTBP2	7553.0	1467.0
CTNNB1	-6022.0	2664.0
CUL1	-2997.0	6875.0
CUX1	-7126.0	4438.0
DERL2	-7153.0	6854.0
DHH	-575.0	3243.0
DKK1	2430.0	-4371.0
DKK2	-5122.0	8325.0
DKK4	-3253.0	2039.0
DLL1	-4076.0	-1816.0
DLL4	-3454.0	4023.0
DUSP10	4557.0	5745.0
DUSP16	-3468.0	8092.0
DUSP6	-5078.0	6412.0
DUSP7	7818.0	-3862.0
DUSP8	4090.0	3420.0
DUSP9	5294.0	-3689.0
EGF	-4765.0	-210.0
EGFR	-6023.0	1902.0
EP300	-2449.0	1336.0
ERBB2	6521.0	-6707.0
ERBB3	3712.0	-75.0
ERBB4	2718.0	2425.0
ERBIN	-100.0	7851.0
ERLEC1	-3854.0	8504.0
ERLIN2	-5110.0	-648.0
ESR1	-187.0	-1356.0
ESR2	2298.0	-2563.0
ESRP1	7191.0	2251.0
ETV6	-2325.0	2640.0
FAM114A2	-4892.0	3284.0
FBXW7	-1739.0	4510.0
FGA	4508.0	5893.0
FGB	3640.0	3338.0
FGF1	-6961.0	3296.0
FGF10	-2375.0	-1761.0
FGF16	3777.0	-2317.0
FGF18	5790.0	-4625.0
FGF2	792.0	3696.0
FGF22	7063.0	-4758.0
FGF9	2653.0	-2366.0
FGFR1	6753.0	-812.0
FGFR1OP2	-6599.0	8434.0
FGFR2	6750.0	6454.0
FGFR3	7673.0	-6608.0
FGFR4	-4841.0	-4690.0
FGG	5980.0	5427.0
FKBP1A	-2857.5	-1534.5
FN1	7489.0	8379.0
FOXO1	6562.0	90.0
FOXO3	7446.0	393.0
FOXO4	257.0	-4431.0
FOXO6	-2112.0	3156.0
FRS2	-3456.0	5571.0
FXR1	-4671.0	5684.0
FYN	-2200.0	6221.0
FZD4	6121.0	5562.0
FZD5	2921.0	2259.0
FZD6	4610.0	5434.0
FZD8	-293.0	-3285.0
GAB1	-4598.0	-3742.0
GAB2	-717.0	7438.0
GOLGA4	-3479.0	-714.0
GRB2	3285.0	1922.0
GSK3A	3838.0	1447.0
GSK3B	-5423.0	7184.0
GTF2F1	373.0	6337.0
GTF2F2	-1458.0	7912.0
HBEGF	-6694.0	-80.0
HDAC1	-3050.0	4701.0
HDAC10	6185.0	-5298.0
HDAC11	6709.0	-5647.0
HDAC2	-6396.0	8620.0
HDAC3	5142.0	-772.0
HDAC4	3270.0	-868.0
HDAC5	3656.0	-6773.0
HDAC6	7878.0	1757.0
HDAC7	5870.0	-2839.0
HDAC8	3387.5	-6320.5
HDAC9	93.0	1799.0
HES1	7353.0	4261.0
HEY1	-484.0	3446.0
HEY2	-4053.0	4359.0
HEYL	-5342.0	-664.0
HGF	-6226.0	7929.0
HHAT	7329.0	-2837.0
HRAS	1503.0	-318.0
HSP90AA1	-7286.0	8742.0
ICOS	-772.0	2670.0
IHH	6365.0	-5234.0
IQGAP1	7427.0	8123.0
IRS1	7064.0	-5549.0
IRS2	-582.0	3045.0
ITGA2B	4961.0	-4170.0
ITGB3	1530.5	4298.5
JAG1	-5328.0	3609.0
JAG2	-2757.0	2836.0
JAK2	-2268.0	5565.0
KANK1	-2615.0	-1388.0
KAT2A	-3442.0	-2675.0
KAT2B	-5780.0	6796.0
KDM7A	5452.0	5988.0
KDR	-4380.0	8170.0
KIAA1549	2144.0	-3229.0
KIT	-1277.0	3432.0
KITLG	-4636.0	7908.0
KL	-5761.0	-554.0
KRAS	-752.0	8587.0
KREMEN1	4699.0	400.0
KREMEN2	-1162.0	-4289.0
KSR1	-476.0	6166.0
KSR2	-7260.0	-2161.0
LCK	-2194.0	5687.0
LMNA	5092.0	-3667.0
LRP5	7865.0	548.0
LRP6	1338.0	1716.0
LRRFIP1	5342.0	6570.0
LYN	-4685.0	8216.0
MAML1	4934.0	2236.0
MAML2	7613.0	4513.0
MAML3	7180.0	5765.0
MAMLD1	6705.0	2789.0
MAP2K1	7852.0	3274.0
MAP2K2	-2882.5	-4769.5
MAP3K11	-195.0	-4556.0
MAPK1	-3928.0	6920.0
MAPK3	5390.0	5167.0
MAPKAP1	-5825.0	6111.0
MARK3	-6565.0	6767.0
MDM2	5569.0	7967.0
MET	-7325.0	3597.0
MIB1	-2528.0	4160.0
MIB2	2255.0	-6580.0
MLST8	-977.0	-1211.0
MPRIP	-2232.0	5169.0
MRAS	6507.0	4369.0
MTOR	-4145.0	-2344.0
MYC	1892.0	3123.0
MYO18A	467.0	-391.0
NCBP1	-6452.0	5580.0
NCBP2	-6814.0	136.0
NCOR1	-7262.0	6244.0
NCOR2	-225.0	-3484.0
NCSTN	6534.0	860.0
NEURL1	1642.0	-2776.0
NEURL1B	6485.0	2017.0
NF1	-3237.0	5332.0
NOTCH1	5759.0	5529.0
NR4A1	2903.0	3535.0
NRAS	3837.0	7903.0
NRG1	-2730.0	4749.0
NRG2	-1154.0	1668.0
NRG4	310.0	-4609.0
OS9	-5615.0	3279.0
PAPSS1	-2058.0	4960.0
PDGFA	4317.0	4142.0
PDGFB	-990.0	-1987.0
PDGFRA	7016.0	8193.0
PDGFRB	-1814.0	8544.0
PDPK1	-4074.0	1936.0
PHB	312.0	5340.0
PIK3AP1	-6075.0	3775.0
PIK3CA	-6347.0	2923.0
PIK3CB	-1756.0	1880.0
PIK3CD	-1968.0	1889.0
PIK3R1	-839.0	8363.0
PIK3R2	1669.5	-3969.5
PIK3R3	3779.5	8820.5
PLCG1	8067.0	-4962.0
POLR2A	4937.0	-1941.0
POLR2B	-675.0	5037.0
POLR2C	2928.0	6859.0
POLR2D	-2762.0	6076.0
POLR2E	7128.0	-3504.0
POLR2F	6184.0	-3058.0
POLR2G	3306.0	-3566.0
POLR2H	4359.0	-4161.0
POLR2I	5890.0	6864.0
POLR2J	1742.0	3424.0
POLR2K	1098.0	7632.0
POLR2L	3697.0	-3808.0
PORCN	3989.0	-4031.0
PPP1CB	-4617.0	8661.0
PPP1CC	6108.0	2839.0
PPP2CA	-5725.0	8237.0
PPP2CB	5588.0	159.0
PPP2R1A	6355.0	3115.0
PPP2R1B	-6463.0	4855.0
PPP2R5A	7319.0	1089.0
PPP2R5B	627.0	5414.0
PPP2R5C	3181.0	8384.0
PPP2R5D	2088.0	5911.0
PPP2R5E	5001.0	2898.0
PRR5	-6098.0	-5369.0
PSEN1	-7020.0	6996.0
PSEN2	-3057.0	-1025.0
PSENEN	-3656.0	5812.0
PSMA1	-6705.0	7838.0
PSMA2	-5464.5	6058.5
PSMA3	-3145.0	7801.0
PSMA4	-6074.0	4688.0
PSMA5	-6660.0	4497.0
PSMA6	-1954.0	8445.0
PSMA7	1612.0	7052.0
PSMA8	649.0	-4004.0
PSMB1	-5281.0	5936.0
PSMB10	3752.0	-908.0
PSMB11	1977.0	-5501.0
PSMB2	1472.0	-4144.0
PSMB3	-3388.0	5539.0
PSMB4	-4941.0	-5852.0
PSMB5	-1638.0	-2409.0
PSMB6	1806.0	-1845.0
PSMB7	-4628.0	-657.0
PSMB8	1080.0	-3793.0
PSMB9	5987.0	-4708.0
PSMC1	-1312.0	4327.0
PSMC2	-6765.0	4648.0
PSMC3	-4285.0	3386.0
PSMC4	-6423.0	7920.0
PSMC5	-4831.0	1120.0
PSMC6	-6851.0	8666.0
PSMD1	-6497.0	8619.0
PSMD10	-1613.0	2576.0
PSMD11	-6873.0	5201.0
PSMD12	-6149.0	8628.0
PSMD13	1898.0	5044.0
PSMD14	-6080.0	8262.0
PSMD2	-6702.0	-3836.0
PSMD3	-2532.0	-3242.0
PSMD4	-5648.0	4994.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
PSMD7	-6943.0	7625.0
PSMD8	1978.0	7546.0
PSMD9	7707.5	-894.5
PSME1	2907.0	5905.0
PSME2	1270.0	-4595.0
PSME3	752.0	7366.0
PSME4	-6830.0	8511.0
PSMF1	5087.0	4771.0
PTEN	-5726.0	8365.0
PTPN11	-3946.0	6142.0
PTPN12	-2782.0	8454.0
QKI	-6268.0	8165.0
RAC1	-1258.0	4008.0
RAC2	-3191.0	6081.0
RAF1	-6377.0	2465.0
RAP1A	-6787.0	8805.0
RAP1B	942.0	8759.0
RBPJ	2571.0	4528.0
RBX1	-391.0	3201.0
RHOG	2039.0	1654.0
RICTOR	493.0	4810.0
RNF43	5429.5	-2614.5
RPS27A	-133.0	-1807.0
RPS6KB2	3493.0	-2458.0
SEL1L	-7264.0	7670.0
SHC1	568.0	1962.0
SHH	-4143.0	-5003.0
SHOC2	-5120.0	8378.0
SKP1	-6803.0	8394.0
SMAD2	2671.0	7154.0
SMAD3	-1639.0	-2520.0
SMAD4	3068.0	901.0
SND1	-6474.0	-3181.0
SNW1	2102.0	8287.0
SOS1	-6566.0	7698.0
SPRED1	-6354.0	8554.0
SPRED2	-1328.0	-5582.0
SPRED3	3740.0	3539.0
SRC	-2657.0	-1643.0
STAT1	-3464.0	-4440.0
STAT3	8126.0	4982.0
STAT5A	2714.0	-3795.0
STAT5B	4664.0	-4634.0
STRN	-4029.0	6779.0
SYVN1	-7005.0	-3045.0
TBL1X	-7106.5	7510.5
TBL1XR1	-1156.0	6145.0
TCF7L2	-4057.0	-2326.0
TENT4A	-2007.0	-3938.0
TGFA	4979.0	2380.0
TGFB1	-1851.0	6152.0
TGFBR1	-2001.0	7866.0
TGFBR2	930.0	7719.0
TLN1	-2076.0	-2832.0
TNKS	7493.0	2959.0
TNKS2	-3624.0	4091.0
TRAK1	7905.0	-999.0
TRAT1	-2279.0	-5760.0
TRIM24	5518.0	4599.0
TSC2	5344.0	-2751.0
UBA52	7488.0	-4269.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
VAV1	-4395.0	5076.0
VCL	-4796.0	7947.0
VCP	-7069.0	5449.0
VWF	7704.0	-1950.0
WDR48	-2737.0	3854.0
YES1	-120.0	7265.0
YWHAB	-4723.0	8579.0
ZC3HAV1	-469.0	-613.0
ZFYVE9	-3503.0	7936.0
ZMYM2	-4816.0	6346.0

---

---

HIV Infection

HIV Infection

metric	value
setSize	222
pMANOVA	1.07e-08
p.adjustMANOVA	3.42e-07
s.dist	0.252
s.diabetes	-0.106
s.mitoG	0.229
p.diabetes	0.00637
p.mitoG	4.51e-09

Top 20 genes

Gene	diabetes	mitoG
PSMC6	-6851.0	8666.0
UBB	-7104.0	8341.0
PSME4	-6830.0	8511.0
SKP1	-6803.0	8394.0
PSMD1	-6497.0	8619.0
PSMD12	-6149.0	8628.0
PSMD7	-6943.0	7625.0
PSMA1	-6705.0	7838.0
GTF2H1	-6106.0	8498.0
UBC	-6013.0	8514.0
PSMC4	-6423.0	7920.0
PSMD14	-6080.0	8262.0
KPNA1	-5632.0	8815.0
VPS37A	-5968.0	8308.0
TCEA1	-5628.0	8792.0
XPO1	-6543.0	7447.0
PSIP1	-6597.0	7229.0
UBAP1	-6158.0	7653.0
CUL5	-5371.0	8605.0
CHMP3	-5181.5	8584.5

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
AAAS	5561.0	-2261.0
AP1B1	5867.0	-3224.0
AP1G1	-6928.0	3255.0
AP1M1	2796.0	-3928.0
AP1M2	7170.0	-121.0
AP1S1	-667.0	-1428.0
AP1S2	-2308.0	7787.0
AP1S3	483.0	-6543.0
AP2A1	3192.0	-2941.0
AP2A2	-6231.0	249.0
AP2B1	-3990.0	7426.0
AP2M1	5073.0	2926.0
AP2S1	587.0	7094.0
ARF1	-5273.0	7470.0
ATP6V1H	-1095.0	8501.0
B2M	5339.0	4978.0
BANF1	3561.0	-458.0
BTRC	3218.0	-5334.0
CCNH	-5547.0	6108.0
CCNK	1018.0	3257.0
CCNT1	-709.0	6941.0
CCNT2	-1826.0	951.0
CCR5	-1106.0	281.0
CD247	1213.0	-5666.0
CD28	-4408.0	5134.0
CD4	409.0	5008.0
CD8B	-2337.5	645.5
CDK7	-258.0	3661.0
CDK9	315.0	-5322.0
CHMP2A	3891.0	6246.0
CHMP2B	-3672.0	8606.0
CHMP3	-5181.5	8584.5
CHMP4B	7103.0	2636.0
CHMP4C	6678.0	1533.0
CHMP5	-4004.0	8542.0
CHMP6	4209.0	-2043.0
CHMP7	-57.0	-2549.0
CTDP1	6939.0	2918.0
CUL5	-5371.0	8605.0
CXCR4	4516.0	7547.0
DOCK2	-5657.0	5085.0
ELL	6782.0	805.0
ELMO1	-4833.0	4917.0
ELOA	7447.0	7874.0
ELOB	6643.0	3269.0
ELOC	-3325.0	7837.0
ERCC2	6295.0	-6411.0
ERCC3	-2263.0	1771.0
FEN1	-277.0	298.0
FURIN	3696.0	-3590.0
FYN	-2200.0	6221.0
GTF2A1	-940.0	5933.0
GTF2A2	505.0	6107.0
GTF2B	-1890.0	6217.0
GTF2E1	-2217.0	6482.0
GTF2E2	-2968.0	2878.0
GTF2F1	373.0	6337.0
GTF2F2	-1458.0	7912.0
GTF2H1	-6106.0	8498.0
GTF2H2	-3368.5	7043.5
GTF2H3	-1824.0	-2008.0
GTF2H4	3818.0	-4105.0
GTF2H5	1998.0	783.0
HCK	-3484.0	-1326.0
HMGA1	7803.0	-1488.0
KPNA1	-5632.0	8815.0
KPNB1	-1668.0	5829.0
LCK	-2194.0	5687.0
LIG1	4884.0	892.0
LIG4	-3349.0	7573.0
MNAT1	1928.0	4358.0
MVB12A	5433.0	3851.0
MVB12B	-659.0	-5360.0
NCBP1	-6452.0	5580.0
NCBP2	-6814.0	136.0
NDC1	6665.0	-1084.0
NEDD4L	1323.0	-3476.0
NELFA	-3692.0	4383.0
NELFB	-4499.0	-5790.0
NELFCD	6086.0	1592.0
NELFE	-2178.0	4789.0
NMT1	-6059.0	6229.0
NMT2	2282.0	6516.0
NUP107	3423.0	7169.0
NUP133	2759.0	-4113.0
NUP153	-4638.0	7763.0
NUP155	6347.0	2192.0
NUP160	-5230.0	1753.0
NUP188	3880.0	-4145.0
NUP205	855.0	6303.0
NUP210	8193.0	-4172.0
NUP214	7802.0	-5326.0
NUP35	-4374.0	-921.0
NUP37	3596.0	1004.0
NUP42	4998.0	-596.0
NUP43	-2270.0	3764.0
NUP50	-4961.0	641.0
NUP54	-3355.0	6010.0
NUP58	2230.0	7116.0
NUP62	4963.0	-4765.0
NUP85	1103.0	-4750.0
NUP88	4817.0	4002.0
NUP93	5331.0	6196.0
NUP98	-2590.0	5122.0
PACS1	7765.0	5342.0
PAK2	-4906.0	6708.0
POLR2A	4937.0	-1941.0
POLR2B	-675.0	5037.0
POLR2C	2928.0	6859.0
POLR2D	-2762.0	6076.0
POLR2E	7128.0	-3504.0
POLR2F	6184.0	-3058.0
POLR2G	3306.0	-3566.0
POLR2H	4359.0	-4161.0
POLR2I	5890.0	6864.0
POLR2J	1742.0	3424.0
POLR2K	1098.0	7632.0
POLR2L	3697.0	-3808.0
POM121	3732.5	-6552.5
POM121C	3732.5	-6552.5
PPIA	4868.0	-469.0
PSIP1	-6597.0	7229.0
PSMA1	-6705.0	7838.0
PSMA2	-5464.5	6058.5
PSMA3	-3145.0	7801.0
PSMA4	-6074.0	4688.0
PSMA5	-6660.0	4497.0
PSMA6	-1954.0	8445.0
PSMA7	1612.0	7052.0
PSMA8	649.0	-4004.0
PSMB1	-5281.0	5936.0
PSMB10	3752.0	-908.0
PSMB11	1977.0	-5501.0
PSMB2	1472.0	-4144.0
PSMB3	-3388.0	5539.0
PSMB4	-4941.0	-5852.0
PSMB5	-1638.0	-2409.0
PSMB6	1806.0	-1845.0
PSMB7	-4628.0	-657.0
PSMB8	1080.0	-3793.0
PSMB9	5987.0	-4708.0
PSMC1	-1312.0	4327.0
PSMC2	-6765.0	4648.0
PSMC3	-4285.0	3386.0
PSMC4	-6423.0	7920.0
PSMC5	-4831.0	1120.0
PSMC6	-6851.0	8666.0
PSMD1	-6497.0	8619.0
PSMD10	-1613.0	2576.0
PSMD11	-6873.0	5201.0
PSMD12	-6149.0	8628.0
PSMD13	1898.0	5044.0
PSMD14	-6080.0	8262.0
PSMD2	-6702.0	-3836.0
PSMD3	-2532.0	-3242.0
PSMD4	-5648.0	4994.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
PSMD7	-6943.0	7625.0
PSMD8	1978.0	7546.0
PSMD9	7707.5	-894.5
PSME1	2907.0	5905.0
PSME2	1270.0	-4595.0
PSME3	752.0	7366.0
PSME4	-6830.0	8511.0
PSMF1	5087.0	4771.0
RAC1	-1258.0	4008.0
RAE1	3041.0	-1934.0
RAN	-4369.0	1437.0
RANBP1	-564.0	4423.0
RANBP2	-4575.0	8132.0
RANGAP1	-2328.0	-1549.0
RBX1	-391.0	3201.0
RCC1	-3025.0	-5367.0
RNGTT	-3753.0	6441.0
RNMT	-3077.0	5647.0
RPS27A	-133.0	-1807.0
SEC13	-1432.0	3604.0
SEH1L	2204.0	6910.0
SKP1	-6803.0	8394.0
SLC25A4	7196.0	-656.0
SLC25A5	7651.0	6887.0
SSRP1	2663.0	4754.0
SUPT16H	-1751.0	7746.0
SUPT4H1	3573.0	2203.0
SUPT5H	5137.0	2571.0
TAF1	-3038.5	3979.5
TAF10	-3030.0	2638.0
TAF11	3706.0	-6076.0
TAF12	-5685.0	2641.0
TAF13	-4258.0	1970.0
TAF15	-1144.0	2020.0
TAF1L	-3038.5	3979.5
TAF2	-5611.0	6188.0
TAF3	1245.0	3100.0
TAF4	2448.0	3472.0
TAF4B	6609.0	4831.0
TAF5	863.0	-388.0
TAF6	-2810.0	1885.0
TAF7	-5754.0	6658.0
TAF9	-3421.0	8678.0
TAF9B	-362.0	4853.0
TBP	3907.0	-217.0
TCEA1	-5628.0	8792.0
TPR	-4239.0	8611.0
TSG101	-708.0	7980.0
UBA52	7488.0	-4269.0
UBAP1	-6158.0	7653.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
VPS28	4871.0	5243.0
VPS37A	-5968.0	8308.0
VPS37B	5639.0	2161.0
VPS37C	5395.0	-224.0
VPS37D	-1556.0	-3123.0
VPS4A	-5731.5	7213.5
VPS4B	2398.0	6175.0
VTA1	-2777.0	104.0
XPO1	-6543.0	7447.0
XRCC4	-4715.0	7026.0
XRCC5	-2388.0	162.0
XRCC6	-1971.0	4034.0

---

---

The citric acid (TCA) cycle and respiratory electron transport

The citric acid (TCA) cycle and respiratory electron transport

metric	value
setSize	168
pMANOVA	1.1e-08
p.adjustMANOVA	3.43e-07
s.dist	0.241
s.diabetes	0.162
s.mitoG	0.178
p.diabetes	0.000288
p.mitoG	7.32e-05

Top 20 genes

Gene	diabetes	mitoG
COX7B	6102.0	8760.0
ACO2	7295.0	7282.0
ATP5PO	6640.5	7456.5
UQCRQ	6271.0	7840.0
MT-ND5	6025.0	8007.0
ME2	6693.0	6628.0
PDK1	8236.0	5206.0
MT-ND1	5618.0	7323.0
MT-ND6	5059.0	8045.0
MT-CO1	6781.0	5983.0
COX6B1	5091.0	7299.0
NDUFA6	6990.0	5257.0
NDUFA12	4539.0	8087.0
NDUFV2	4127.0	8731.0
NDUFB8	4901.5	6790.5
PDP1	4298.0	7517.0
UCP2	6987.0	4595.0
ATP5PD	5135.0	6133.0
CS	5645.0	5457.0
NDUFA7	7477.5	4100.5

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
ACAD9	-4848.0	-2818.0
ACO2	7295.0	7282.0
ADHFE1	-6733.0	240.0
ATP5F1A	6316.0	1471.0
ATP5F1B	1691.0	1750.0
ATP5F1C	164.0	8242.0
ATP5F1D	5225.0	673.0
ATP5F1E	6241.0	-5774.0
ATP5MC3	6278.0	-5724.0
ATP5ME	3268.0	3202.0
ATP5MF	6860.0	-1957.0
ATP5MG	5923.5	564.5
ATP5PB	1124.0	5544.0
ATP5PD	5135.0	6133.0
ATP5PF	710.0	7012.0
ATP5PO	6640.5	7456.5
BSG	-3166.0	5032.0
COQ10A	7831.0	-5063.0
COQ10B	219.0	7422.0
COX11	742.0	-1169.0
COX14	2703.0	-3376.0
COX16	-3433.0	7416.0
COX18	5019.0	1575.0
COX19	-2099.0	3124.0
COX20	-4714.0	6792.0
COX4I1	6324.0	-2473.0
COX5B	7740.0	-2295.0
COX6A1	5658.0	-2138.0
COX6B1	5091.0	7299.0
COX6C	7537.0	1755.0
COX7A2L	4007.0	4780.0
COX7B	6102.0	8760.0
COX7C	4066.0	-5285.0
COX8A	5622.0	-4787.0
CS	5645.0	5457.0
CYC1	7497.0	-4809.0
D2HGDH	-4629.0	-6471.0
DLAT	3962.0	2209.0
DLD	-2523.0	7607.0
DLST	6249.0	251.0
DMAC2L	1623.0	-997.0
ECSIT	-3596.0	1408.0
ETFA	-4953.0	3129.0
ETFB	5896.0	-2345.0
ETFDH	-5320.0	8131.0
FAHD1	-5635.0	4647.0
FH	1716.0	7771.0
GLO1	-6305.0	1741.0
GSTZ1	-3082.0	5598.0
HAGH	1822.0	7296.0
IDH2	155.0	1563.0
IDH3A	-958.0	7080.0
IDH3B	3081.0	573.0
IDH3G	-4880.0	6728.0
L2HGDH	1057.0	-1650.0
LDHA	-5897.0	843.0
LDHAL6B	2680.0	-6086.0
LDHB	5412.5	4669.5
LRPPRC	3831.0	6319.0
MDH2	3713.0	4456.0
ME1	-7337.0	4579.0
ME2	6693.0	6628.0
ME3	1300.0	-1217.0
MPC1	-3373.0	8178.0
MPC2	5946.0	-6209.0
MT-ATP6	-5818.0	8744.0
MT-ATP8	3277.0	6153.0
MT-CO1	6781.0	5983.0
MT-CO2	293.0	-1711.0
MT-CO3	2273.0	6269.0
MT-CYB	3577.0	8110.0
MT-ND1	5618.0	7323.0
MT-ND2	-1693.0	8626.0
MT-ND3	1835.0	8689.0
MT-ND4	1752.0	7883.0
MT-ND5	6025.0	8007.0
MT-ND6	5059.0	8045.0
NDUFA1	2104.0	-4989.0
NDUFA10	-1891.0	7765.0
NDUFA11	7279.5	474.5
NDUFA12	4539.0	8087.0
NDUFA13	4768.0	-2346.0
NDUFA2	5261.0	-6155.0
NDUFA3	4319.0	82.0
NDUFA4	-5102.0	8096.0
NDUFA5	7846.0	2875.0
NDUFA6	6990.0	5257.0
NDUFA7	7477.5	4100.5
NDUFA8	5308.0	4366.0
NDUFA9	3756.0	-5331.0
NDUFAB1	251.0	2742.0
NDUFAF1	-5470.0	1013.0
NDUFAF2	-2453.0	6013.0
NDUFAF3	-983.0	-2862.0
NDUFAF4	-5532.0	7346.0
NDUFAF5	1712.0	1907.0
NDUFAF6	-2110.0	-2934.0
NDUFAF7	1694.0	6697.0
NDUFB1	5672.0	711.0
NDUFB10	4853.0	-1340.0
NDUFB11	1539.0	7247.0
NDUFB2	2034.0	-5126.0
NDUFB3	-2553.0	-4632.0
NDUFB4	-5247.0	8719.0
NDUFB5	450.0	2312.0
NDUFB6	6783.0	848.0
NDUFB7	5336.0	2347.0
NDUFB8	4901.5	6790.5
NDUFB9	6765.0	1224.0
NDUFC1	1620.0	3968.0
NDUFC2	4564.5	-5546.5
NDUFS1	-1094.0	6402.0
NDUFS2	1841.0	4991.0
NDUFS3	4184.0	-2145.0
NDUFS4	4791.0	4043.0
NDUFS5	5126.0	-4249.0
NDUFS6	2287.0	6500.0
NDUFS7	7367.0	-5947.0
NDUFS8	1961.0	2910.0
NDUFV1	4313.0	-2431.0
NDUFV2	4127.0	8731.0
NDUFV3	-5257.0	5625.0
NNT	4576.0	4716.0
NUBPL	-1636.0	-1999.0
OGDH	6393.0	3583.0
PDHA1	-16.0	7978.0
PDHB	182.0	8175.0
PDHX	-1471.0	7544.0
PDK1	8236.0	5206.0
PDK2	8043.0	-1425.0
PDK3	-7135.0	6177.0
PDK4	3864.0	4092.0
PDP1	4298.0	7517.0
PDP2	-1525.0	-1465.0
PDPR	-1560.0	-1589.0
PM20D1	-4304.0	-1376.0
PPARD	-6955.0	-1980.0
RXRA	-5143.0	1552.0
SCO1	-3365.0	57.0
SCO2	-3687.0	2948.0
SDHA	3626.5	-1630.5
SDHB	3180.0	7355.0
SDHC	-860.0	834.0
SDHD	6887.5	1213.5
SLC16A1	-7027.0	5763.0
SLC16A3	5619.0	-3522.0
SLC16A8	87.0	-4934.0
SLC25A14	-1689.0	-3486.0
SLC25A27	1702.0	-2334.0
SUCLA2	-5284.0	8723.0
SUCLG1	1641.0	7641.0
SUCLG2	2515.0	3596.0
SURF1	2134.0	4131.0
TACO1	-3888.0	3315.0
TIMMDC1	-2651.0	-2924.0
TMEM126B	-6725.0	3713.0
TRAP1	-6124.0	2675.0
UCP2	6987.0	4595.0
UCP3	3545.0	-4364.0
UQCR10	6187.0	697.0
UQCR11	5012.5	-3179.5
UQCRB	-410.0	8334.0
UQCRC1	5627.0	1729.0
UQCRC2	2236.0	6852.0
UQCRFS1	3296.0	-3981.0
UQCRH	5780.5	-5189.5
UQCRQ	6271.0	7840.0
VDAC1	6.0	6549.0

---

---

Programmed Cell Death

Programmed Cell Death

metric	value
setSize	175
pMANOVA	1.23e-08
p.adjustMANOVA	3.74e-07
s.dist	0.272
s.diabetes	-0.0616
s.mitoG	0.265
p.diabetes	0.161
p.mitoG	1.59e-09

Top 20 genes

Gene	diabetes	mitoG
HSP90AA1	-7286	8742
PSMC6	-6851	8666
UBB	-7104	8341
PSME4	-6830	8511
PSMD1	-6497	8619
DYNLL1	-6952	7645
PSMD12	-6149	8628
PSMD7	-6943	7625
PSMA1	-6705	7838
UBC	-6013	8514
PSMC4	-6423	7920
PSMD14	-6080	8262
KPNA1	-5632	8815
YWHAH	-6051	7949
YWHAZ	-5614	8512
CASP8	-5258	8694
BCAP31	-6657	6845
PSMD5	-6156	7150
DNM1L	-4825	8774
YWHAB	-4723	8579

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
ACIN1	1868.0	-3396.0
ADD1	-5137.0	969.0
AKT1	4859.0	7244.0
AKT2	-4939.0	3281.0
AKT3	-375.0	7862.0
APAF1	-1681.0	4531.0
APC	4716.0	8376.0
APIP	1979.0	6328.0
APPL1	940.0	7089.0
ARHGAP10	-6608.0	-2003.0
AVEN	-2870.0	-1960.0
BAD	-2216.0	-4664.0
BAK1	7177.0	3473.0
BAX	6141.0	-6683.0
BCAP31	-6657.0	6845.0
BCL2	-1449.0	-2113.0
BCL2L1	1254.0	3623.0
BCL2L11	7084.0	668.0
BID	-6112.0	-270.0
BIRC2	-4230.0	3665.0
BIRC3	6091.0	6158.0
BMF	-245.0	3162.0
BMX	5552.0	4493.0
C1QBP	4206.0	1754.0
CASP3	4881.0	3606.0
CASP6	2935.0	3986.0
CASP7	6240.0	526.0
CASP8	-5258.0	8694.0
CASP9	2469.0	-5751.0
CD14	4081.0	6994.0
CDC37	-682.0	-4414.0
CDH1	-1038.0	5837.0
CFLAR	-4054.0	2224.0
CLSPN	3534.0	-3857.0
CTNNB1	-6022.0	2664.0
DAPK1	-3680.0	770.0
DAPK2	-2126.0	4028.0
DAPK3	3.0	-5598.0
DBNL	3890.0	-1155.0
DFFA	4899.0	-803.0
DFFB	6044.0	-6041.0
DIABLO	-3178.0	5083.0
DNM1L	-4825.0	8774.0
DSG2	7918.0	5394.0
DSP	7655.0	6828.0
DYNLL1	-6952.0	7645.0
DYNLL2	4932.0	-5028.0
E2F1	4935.0	-488.0
FADD	6301.0	-5424.0
FAS	3093.0	7580.0
FASLG	834.0	4880.0
FLOT1	6842.0	-1838.0
FLOT2	6512.0	1544.0
FNTA	-593.0	5888.0
GAS2	-7224.0	5159.0
GSN	7535.0	7997.0
GZMB	270.0	-2421.0
H1-0	7817.0	6665.0
H1-1	4222.0	7277.0
H1-2	7795.0	4082.0
H1-3	3925.0	-879.0
H1-4	7392.0	8249.0
H1-5	-1450.0	1228.0
HMGB1	2876.0	8283.0
HMGB2	6857.0	1304.0
HSP90AA1	-7286.0	8742.0
KPNA1	-5632.0	8815.0
KPNB1	-1668.0	5829.0
LMNA	5092.0	-3667.0
LMNB1	6899.0	-4624.0
LY96	-4879.0	364.0
MAGED1	-6546.0	5010.0
MAPK1	-3928.0	6920.0
MAPK3	5390.0	5167.0
MAPK8	-3252.0	1695.0
MAPT	-6403.0	3350.0
MLKL	6050.0	1003.0
NMT1	-6059.0	6229.0
OCLN	6047.0	-451.0
OGT	-4547.0	-6169.0
OMA1	-4909.0	-736.0
OPA1	1629.0	7798.0
PAK2	-4906.0	6708.0
PELI1	2295.0	5683.0
PLEC	8057.0	180.0
PMAIP1	2215.0	5575.0
PPP1R13B	3221.0	7424.0
PPP3CC	5563.0	4840.0
PPP3R1	2835.5	8199.5
PRKCD	365.0	1901.0
PRKCQ	-2002.0	-3514.0
PSMA1	-6705.0	7838.0
PSMA2	-5464.5	6058.5
PSMA3	-3145.0	7801.0
PSMA4	-6074.0	4688.0
PSMA5	-6660.0	4497.0
PSMA6	-1954.0	8445.0
PSMA7	1612.0	7052.0
PSMA8	649.0	-4004.0
PSMB1	-5281.0	5936.0
PSMB10	3752.0	-908.0
PSMB11	1977.0	-5501.0
PSMB2	1472.0	-4144.0
PSMB3	-3388.0	5539.0
PSMB4	-4941.0	-5852.0
PSMB5	-1638.0	-2409.0
PSMB6	1806.0	-1845.0
PSMB7	-4628.0	-657.0
PSMB8	1080.0	-3793.0
PSMB9	5987.0	-4708.0
PSMC1	-1312.0	4327.0
PSMC2	-6765.0	4648.0
PSMC3	-4285.0	3386.0
PSMC4	-6423.0	7920.0
PSMC5	-4831.0	1120.0
PSMC6	-6851.0	8666.0
PSMD1	-6497.0	8619.0
PSMD10	-1613.0	2576.0
PSMD11	-6873.0	5201.0
PSMD12	-6149.0	8628.0
PSMD13	1898.0	5044.0
PSMD14	-6080.0	8262.0
PSMD2	-6702.0	-3836.0
PSMD3	-2532.0	-3242.0
PSMD4	-5648.0	4994.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
PSMD7	-6943.0	7625.0
PSMD8	1978.0	7546.0
PSMD9	7707.5	-894.5
PSME1	2907.0	5905.0
PSME2	1270.0	-4595.0
PSME3	752.0	7366.0
PSME4	-6830.0	8511.0
PSMF1	5087.0	4771.0
PTK2	2264.0	6997.0
RIPK1	-2977.0	5088.0
RIPK3	1577.0	1519.0
ROCK1	-2765.0	8654.0
RPS27A	-133.0	-1807.0
SATB1	-1732.0	4168.0
SDCBP	5668.0	4540.0
SFN	3916.0	5704.0
SPTAN1	7051.0	7359.0
STAT3	8126.0	4982.0
STK24	4748.0	-214.0
STK26	-1443.0	7201.0
STUB1	4177.0	-2823.0
TFDP1	-6289.0	4476.0
TFDP2	7449.0	3780.0
TICAM1	-1539.0	-3874.0
TJP1	4021.0	8531.0
TJP2	-3964.5	6046.5
TLR4	-4128.0	8470.0
TNFSF10	-6011.0	987.0
TP53	2557.0	-3561.0
TP53BP2	6638.0	5316.0
TP63	-3604.0	1254.0
TP73	2068.0	84.0
TRADD	-1318.0	-2687.0
TRAF2	3405.0	-3806.0
UACA	5605.0	7217.0
UBA52	7488.0	-4269.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
UNC5A	-1287.0	-1741.0
UNC5B	6777.0	5303.0
VIM	5500.0	7940.0
XIAP	-4862.0	7852.0
YWHAB	-4723.0	8579.0
YWHAE	-2079.0	7315.0
YWHAG	-5348.0	1700.0
YWHAH	-6051.0	7949.0
YWHAQ	3046.0	8675.0
YWHAZ	-5614.0	8512.0

---

---

Cytokine Signaling in Immune system

Cytokine Signaling in Immune system

metric	value
setSize	736
pMANOVA	1.47e-08
p.adjustMANOVA	4.37e-07
s.dist	0.14
s.diabetes	-0.0604
s.mitoG	0.126
p.diabetes	0.00556
p.mitoG	6.86e-09

Top 20 genes

Gene	diabetes	mitoG
HSP90AA1	-7286	8742
HSP90B1	-7279	8368
HSPA8	-7307	8180
RAP1A	-6787	8805
PSMC6	-6851	8666
UBB	-7104	8341
CANX	-6936	8532
KPNA4	-6802	8691
EIF4G2	-6764	8704
CAPZA1	-6942	8474
HMOX1	-7076	8232
PSME4	-6830	8511
UBE2E1	-6831	8405
SKP1	-6803	8394
IL13RA1	-7265	7820
PSMD1	-6497	8619
ITGB1	-6241	8758
JAK1	-6481	8390
SPRED1	-6354	8554
PSMD12	-6149	8628

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
AAAS	5561.0	-2261.0
ABCE1	-5766.0	8831.0
ABHD17A	6198.0	-5972.0
ABHD17B	-5256.0	7454.0
ABHD17C	2020.0	-2013.0
ACTN2	-160.0	4310.0
ADAM17	-5121.0	3275.0
ADAR	4854.0	-5902.0
AGER	5844.0	-3308.0
AIP	-549.0	3479.0
AKT1	4859.0	7244.0
AKT2	-4939.0	3281.0
ALOX5	5079.0	-1468.0
ANGPT1	-6415.0	8155.0
ANXA1	7055.0	8221.0
ANXA2	-337.0	8406.0
APBB1IP	-5251.0	-2322.0
APP	-5115.0	6758.0
ARAF	4130.0	-5879.0
ARF1	-5273.0	7470.0
ARIH1	-4566.0	6687.0
ARL2	7475.0	-2736.0
ARRB1	-6250.0	3030.0
ARRB2	-3644.0	681.0
ARTN	115.0	1230.0
ATF1	-4649.0	7196.0
ATF2	-4162.0	7780.0
B2M	5339.0	4978.0
BATF	574.0	313.0
BCL2	-1449.0	-2113.0
BCL2L1	1254.0	3623.0
BCL6	-4525.0	36.0
BIRC2	-4230.0	3665.0
BIRC3	6091.0	6158.0
BIRC5	-3018.0	-2773.0
BLNK	6748.0	-965.0
BOLA2	5917.5	-478.5
BRAF	-6284.0	4955.0
BRAP	-3859.0	735.0
BRWD1	3941.0	-3907.0
BST2	-460.0	-4229.0
BTC	7701.0	1951.0
BTRC	3218.0	-5334.0
CALM1	-4401.0	8702.0
CAMK2A	-2272.0	4664.0
CAMK2B	2551.0	5253.0
CAMK2G	5581.0	-3540.0
CANX	-6936.0	8532.0
CAPZA1	-6942.0	8474.0
CASP1	-1051.0	1558.0
CASP3	4881.0	3606.0
CBL	-6462.0	4306.0
CCL11	3017.0	670.0
CCL19	1486.0	-2403.0
CCL2	-1079.0	3167.0
CCL22	-3491.0	4025.0
CCL4	129.5	1818.5
CCL5	-3367.0	3393.0
CCND1	7933.0	-1628.0
CCR1	-3507.0	4981.0
CCR2	-6442.0	5692.0
CCR5	-1106.0	281.0
CD27	1564.0	-5785.0
CD36	-7328.0	6006.0
CD4	409.0	5008.0
CD40	-1092.0	450.0
CD44	-4381.0	6982.0
CD80	-3453.0	3286.0
CD86	-2679.0	5554.0
CDC42	-5961.0	8129.0
CDKN1A	7594.0	6372.0
CEBPD	3288.0	6984.0
CFL1	-1720.0	8321.0
CHUK	-3701.0	8556.0
CIITA	-5946.0	-2698.0
CISH	-419.0	-2121.0
CLCF1	6318.0	-5706.0
CNKSR1	7454.0	1081.0
CNKSR2	3628.0	-207.0
CNN2	-2669.0	6553.0
CNTF	3748.0	3077.0
CNTFR	7636.0	-2686.0
COL1A2	416.0	5053.0
CREB1	-6809.0	5166.0
CRK	-3124.0	6926.0
CRKL	-4195.0	3246.0
CRLF1	5990.0	141.0
CRLF2	4692.0	-3614.0
CSF1	-2451.0	7450.0
CSF1R	-6805.0	2322.0
CSF2RA	-2892.0	-5044.0
CSF2RB	-5554.0	-817.0
CSF3R	-5607.0	5881.0
CSK	-5802.0	-2193.0
CTF1	601.0	-5358.0
CUL1	-2997.0	6875.0
CUL3	-3105.0	8488.0
CXCL10	-3846.0	6517.0
DAB2IP	7371.0	2495.0
DDX58	7214.0	-485.0
DLG1	-1980.0	6587.0
DLG2	5325.0	-4513.0
DLG3	6540.0	94.0
DLG4	3487.0	-1410.0
DUSP1	-2905.0	-1666.0
DUSP10	4557.0	5745.0
DUSP16	-3468.0	8092.0
DUSP2	1065.0	-4070.0
DUSP4	-2461.0	-1440.0
DUSP5	4923.0	4971.0
DUSP6	-5078.0	6412.0
DUSP7	7818.0	-3862.0
DUSP8	4090.0	3420.0
DUSP9	5294.0	-3689.0
EBI3	3333.0	2001.0
EDA	4324.0	6384.0
EDA2R	8226.0	6933.0
EDAR	-769.0	-2084.0
EDARADD	6526.0	-6016.0
EGF	-4765.0	-210.0
EGFR	-6023.0	1902.0
EGR1	1105.0	4313.0
EIF2AK2	4174.0	5292.0
EIF4A1	5335.0	61.0
EIF4A2	-6848.0	-699.0
EIF4A3	2375.0	2229.0
EIF4E	-4500.0	8429.0
EIF4E2	1435.0	5962.0
EIF4E3	-232.0	4408.0
EIF4G1	-5996.0	5731.0
EIF4G2	-6764.0	8704.0
EIF4G3	-7083.0	1872.0
ELK1	3201.0	-1060.0
ERBB2	6521.0	-6707.0
ERBB3	3712.0	-75.0
ERBB4	2718.0	2425.0
F13A1	3019.0	4962.0
FASLG	834.0	4880.0
FBXW11	-3788.0	3125.0
FCER2	-3304.0	-718.0
FCGR1A	-5675.5	4265.5
FCGR1B	-5675.5	4265.5
FGA	4508.0	5893.0
FGB	3640.0	3338.0
FGF1	-6961.0	3296.0
FGF10	-2375.0	-1761.0
FGF16	3777.0	-2317.0
FGF18	5790.0	-4625.0
FGF2	792.0	3696.0
FGF22	7063.0	-4758.0
FGF9	2653.0	-2366.0
FGFR1	6753.0	-812.0
FGFR2	6750.0	6454.0
FGFR3	7673.0	-6608.0
FGFR4	-4841.0	-4690.0
FGG	5980.0	5427.0
FLNA	-4704.0	7432.0
FLNB	7947.0	3634.0
FLT3	-3889.0	-337.0
FLT3LG	-882.0	438.0
FN1	7489.0	8379.0
FNTA	-593.0	5888.0
FNTB	3819.5	1858.5
FOS	827.0	3751.0
FOXO1	6562.0	90.0
FOXO3	7446.0	393.0
FRS2	-3456.0	5571.0
FRS3	-2543.0	-5274.0
FSCN1	6020.0	3898.0
FYN	-2200.0	6221.0
GAB1	-4598.0	-3742.0
GAB2	-717.0	7438.0
GATA3	7885.0	-1653.0
GBP2	-5242.0	4895.0
GBP5	-2160.0	-96.0
GBP6	-7251.0	-187.0
GDNF	6180.0	-48.0
GFRA1	-5626.0	-3174.0
GFRA2	-4307.0	-618.0
GFRA3	-307.0	-1564.0
GFRA4	6087.0	3762.0
GHR	-6922.0	4790.0
GOLGA7	-2069.0	6586.0
GRB2	3285.0	1922.0
GRIN1	3290.0	-5743.0
GRIN2B	-40.0	2055.0
GRIN2D	925.0	-2664.0
GSTO1	8023.0	4922.0
H3C15	7988.0	2080.0
HAVCR2	-6021.0	6627.0
HBEGF	-6694.0	-80.0
HCK	-3484.0	-1326.0
HGF	-6226.0	7929.0
HIF1A	7374.0	8562.0
HLA-DQB1	-4730.5	1217.5
HLA-DQB2	-4730.5	1217.5
HLA-DRB1	1762.5	-4711.5
HLA-DRB5	1762.5	-4711.5
HLA-E	3698.5	-6121.5
HLA-G	3698.5	-6121.5
HMGB1	2876.0	8283.0
HMOX1	-7076.0	8232.0
HNRNPA2B1	-2132.0	-151.0
HNRNPDL	8075.0	2325.0
HNRNPF	-4812.0	5595.0
HRAS	1503.0	-318.0
HSP90AA1	-7286.0	8742.0
HSP90B1	-7279.0	8368.0
HSPA8	-7307.0	8180.0
HSPA9	-566.0	8181.0
ICAM1	7342.0	7752.0
ICMT	-315.0	-1207.0
IFI35	236.0	-2661.0
IFIT2	4952.0	4307.0
IFIT3	4120.0	6607.0
IFITM1	6414.0	8796.0
IFITM2	6414.0	8796.0
IFITM3	6414.0	8796.0
IFNA1	1047.0	-1753.0
IFNA10	1047.0	-1753.0
IFNA14	1047.0	-1753.0
IFNA16	1047.0	-1753.0
IFNA17	1047.0	-1753.0
IFNA2	1047.0	-1753.0
IFNA21	1047.0	-1753.0
IFNA4	1047.0	-1753.0
IFNA5	1047.0	-1753.0
IFNA6	1047.0	-1753.0
IFNA7	1047.0	-1753.0
IFNA8	1047.0	-1753.0
IFNAR1	-1479.0	4534.0
IFNAR2	-850.5	5706.5
IFNGR1	-4655.0	6148.0
IFNGR2	4633.0	5019.0
IFNLR1	5476.0	1139.0
IKBKB	-1785.0	-5829.0
IKBKG	3700.0	-677.0
IL10RA	-6326.0	3465.0
IL10RB	-4532.0	-4965.0
IL11	-3409.0	1307.0
IL11RA	-5781.5	-1048.5
IL12RB1	4540.0	-5099.0
IL12RB2	28.0	-159.0
IL13RA1	-7265.0	7820.0
IL15	-4138.0	-2350.0
IL15RA	4967.0	-4955.0
IL16	-238.0	5474.0
IL17C	-1887.0	-3210.0
IL17F	243.0	-3130.0
IL17RA	-520.0	-3946.0
IL17RB	6676.0	-3477.0
IL17RC	6671.0	-6327.0
IL17RD	2410.0	2168.0
IL17RE	6664.0	4868.0
IL18	4167.0	-3592.0
IL18BP	5260.0	-3368.0
IL18R1	1538.0	151.0
IL18RAP	-2806.0	2792.0
IL1A	-1142.0	1688.0
IL1B	-6242.0	3978.0
IL1R1	3443.0	7288.0
IL1R2	-2817.0	6793.0
IL1RAP	1964.0	5164.0
IL1RAPL1	2419.0	-1284.0
IL1RL1	-1839.0	1060.0
IL1RL2	6863.0	1080.0
IL20RB	6541.0	-1964.0
IL21R	-2522.0	-4656.0
IL22RA1	-4036.0	-1035.0
IL23A	-2852.0	2958.0
IL23R	1187.0	2344.0
IL27RA	-2587.0	1948.0
IL2RA	62.0	288.0
IL2RB	-4367.0	-223.0
IL2RG	-4350.5	-961.5
IL31RA	2141.0	-1614.0
IL33	7328.0	7911.0
IL34	-7341.0	1594.0
IL36G	-2911.0	-6370.0
IL36RN	-1984.0	3989.0
IL4	4157.0	-5043.0
IL4R	647.0	5708.0
IL5RA	-3525.0	-463.0
IL6R	-730.0	6215.0
IL6ST	-6703.0	6610.0
IL7	1813.0	-1239.0
IL7R	-5696.0	8026.0
IL9R	-50.0	-4403.0
INPP5D	-1230.0	5535.0
INPPL1	-1829.0	-4396.0
IP6K2	6791.0	1576.0
IQGAP1	7427.0	8123.0
IRAK1	-3742.0	4800.0
IRAK2	-879.0	-1594.0
IRAK3	4675.0	4623.0
IRAK4	2339.0	4636.0
IRF1	3086.0	3498.0
IRF2	542.0	-3491.0
IRF3	806.0	-4184.0
IRF4	-1439.0	-700.0
IRF5	-6958.0	-2707.0
IRF6	-5647.0	2429.0
IRF7	-4522.0	2058.0
IRF8	3503.0	-706.0
IRF9	94.0	-3372.0
IRS1	7064.0	-5549.0
IRS2	-582.0	3045.0
ISG15	-1124.0	-2998.0
ISG20	-4950.0	8034.0
ITGA2B	4961.0	-4170.0
ITGAM	3292.0	5515.0
ITGAX	-5859.0	2296.0
ITGB1	-6241.0	8758.0
ITGB2	-5238.0	412.0
ITGB3	1530.5	4298.5
JAK1	-6481.0	8390.0
JAK2	-2268.0	5565.0
JAK3	7556.0	-6301.0
JUN	581.0	5314.0
JUNB	4544.0	2430.0
KBTBD7	-6874.5	7477.5
KIT	-1277.0	3432.0
KITLG	-4636.0	7908.0
KL	-5761.0	-554.0
KPNA1	-5632.0	8815.0
KPNA2	2229.0	5432.0
KPNA3	-1498.0	8389.0
KPNA4	-6802.0	8691.0
KPNB1	-1668.0	5829.0
KRAS	-752.0	8587.0
KSR1	-476.0	6166.0
KSR2	-7260.0	-2161.0
LAMA5	8212.0	-6404.0
LAMTOR2	-2847.0	1280.0
LAMTOR3	2323.0	4870.0
LAT	1869.0	-481.0
LBP	4550.0	7403.0
LCK	-2194.0	5687.0
LCN2	5811.0	8293.0
LCP1	-6656.0	4745.0
LIF	352.0	2557.0
LIFR	4755.0	4346.0
LMNB1	6899.0	-4624.0
LRRC7	-883.0	-2663.0
LTB	-2020.0	3847.0
LTBR	1443.0	561.0
LYN	-4685.0	8216.0
LYPLA1	-6790.0	7638.0
MAOA	3741.0	-492.0
MAP2K1	7852.0	3274.0
MAP2K2	-2882.5	-4769.5
MAP2K3	3494.0	-249.0
MAP2K4	2621.0	5572.0
MAP2K6	5640.0	-4115.0
MAP2K7	3505.0	-3383.0
MAP3K11	-195.0	-4556.0
MAP3K14	-4228.0	558.0
MAP3K3	729.0	6115.0
MAP3K7	1594.0	7480.0
MAP3K8	656.0	2671.0
MAPK1	-3928.0	6920.0
MAPK10	-2089.0	-137.0
MAPK11	4349.0	2889.0
MAPK12	3182.0	6505.0
MAPK14	-6337.0	-1012.0
MAPK3	5390.0	5167.0
MAPK7	4710.0	-703.0
MAPK8	-3252.0	1695.0
MAPK9	2849.0	6624.0
MAPKAPK2	-2527.0	4587.0
MAPKAPK3	7267.0	-4297.0
MARK3	-6565.0	6767.0
MCL1	6260.0	-1020.0
MEF2A	-2071.0	7495.0
MEF2C	-1905.0	8451.0
MET	-7325.0	3597.0
MID1	-3606.0	-3077.0
MIF	8230.0	5317.0
MMP2	1375.0	7816.0
MMP3	-598.0	1929.0
MMP9	-5717.0	1502.0
MRAS	6507.0	4369.0
MSN	-1294.0	5246.0
MT2A	8239.0	7031.0
MTAP	-2386.0	7629.0
MUC1	7970.0	3179.0
MX1	-6771.0	351.0
MYC	1892.0	3123.0
MYD88	-5933.0	3612.0
NANOG	-2036.5	-2968.5
NCAM1	-2962.0	3965.0
NDC1	6665.0	-1084.0
NDN	894.0	5072.0
NEDD4	1235.0	7804.0
NEFL	7769.0	-859.0
NF1	-3237.0	5332.0
NFKB1	5449.0	4035.0
NFKB2	2120.0	-4751.0
NFKBIA	1631.0	4830.0
NFKBIB	3850.0	467.0
NKIRAS1	-5446.0	5927.0
NKIRAS2	7425.0	286.0
NOD1	5283.0	4068.0
NOD2	-6286.0	2681.0
NOS2	-1104.0	4079.0
NRAS	3837.0	7903.0
NRG1	-2730.0	4749.0
NRG2	-1154.0	1668.0
NRG4	310.0	-4609.0
NRTN	2219.0	-5311.0
NUP107	3423.0	7169.0
NUP133	2759.0	-4113.0
NUP153	-4638.0	7763.0
NUP155	6347.0	2192.0
NUP160	-5230.0	1753.0
NUP188	3880.0	-4145.0
NUP205	855.0	6303.0
NUP210	8193.0	-4172.0
NUP214	7802.0	-5326.0
NUP35	-4374.0	-921.0
NUP37	3596.0	1004.0
NUP42	4998.0	-596.0
NUP43	-2270.0	3764.0
NUP50	-4961.0	641.0
NUP54	-3355.0	6010.0
NUP58	2230.0	7116.0
NUP62	4963.0	-4765.0
NUP85	1103.0	-4750.0
NUP88	4817.0	4002.0
NUP93	5331.0	6196.0
NUP98	-2590.0	5122.0
OAS1	3456.0	-6726.0
OAS2	-6685.0	-1827.0
OAS3	-5020.0	-5338.0
OASL	-5463.0	2584.0
OPRD1	-1261.0	-2986.0
OPRM1	-459.0	-2620.0
OSMR	5259.0	8374.0
P4HB	-6743.0	5398.0
PAK2	-4906.0	6708.0
PAQR3	3846.0	-6426.0
PDCD4	8018.0	3871.0
PDE12	-6351.0	7766.0
PDE3B	2729.0	6182.0
PDE6D	1227.0	4398.0
PDGFA	4317.0	4142.0
PDGFB	-990.0	-1987.0
PDGFRA	7016.0	8193.0
PDGFRB	-1814.0	8544.0
PDPK1	-4074.0	1936.0
PEA15	-39.0	7548.0
PELI1	2295.0	5683.0
PELI2	4968.0	-157.0
PELI3	7915.0	-6062.0
PHB	312.0	5340.0
PIAS1	3194.0	2440.0
PIK3C3	1518.0	-2612.0
PIK3CA	-6347.0	2923.0
PIK3CB	-1756.0	1880.0
PIK3CD	-1968.0	1889.0
PIK3R1	-839.0	8363.0
PIK3R2	1669.5	-3969.5
PIK3R3	3779.5	8820.5
PIK3R4	4272.0	-1214.0
PIM1	-3615.0	5315.0
PIN1	1926.0	-1497.0
PITPNA	-912.0	8721.0
PLCG1	8067.0	-4962.0
PML	6152.0	-5597.0
POM121	3732.5	-6552.5
POM121C	3732.5	-6552.5
POMC	3685.0	-2222.0
POU2F1	6232.0	5561.0
PPIA	4868.0	-469.0
PPM1B	-3071.5	4017.5
PPP1CB	-4617.0	8661.0
PPP1CC	6108.0	2839.0
PPP2CA	-5725.0	8237.0
PPP2CB	5588.0	159.0
PPP2R1A	6355.0	3115.0
PPP2R1B	-6463.0	4855.0
PPP2R5A	7319.0	1089.0
PPP2R5B	627.0	5414.0
PPP2R5C	3181.0	8384.0
PPP2R5D	2088.0	5911.0
PPP2R5E	5001.0	2898.0
PPP5C	565.0	5319.0
PRKACA	-530.0	15.0
PRKCD	365.0	1901.0
PRKCQ	-2002.0	-3514.0
PRKG2	1125.0	-4521.0
PRLR	8156.0	809.0
PSMA1	-6705.0	7838.0
PSMA2	-5464.5	6058.5
PSMA3	-3145.0	7801.0
PSMA4	-6074.0	4688.0
PSMA5	-6660.0	4497.0
PSMA6	-1954.0	8445.0
PSMA7	1612.0	7052.0
PSMA8	649.0	-4004.0
PSMB1	-5281.0	5936.0
PSMB10	3752.0	-908.0
PSMB11	1977.0	-5501.0
PSMB2	1472.0	-4144.0
PSMB3	-3388.0	5539.0
PSMB4	-4941.0	-5852.0
PSMB5	-1638.0	-2409.0
PSMB6	1806.0	-1845.0
PSMB7	-4628.0	-657.0
PSMB8	1080.0	-3793.0
PSMB9	5987.0	-4708.0
PSMC1	-1312.0	4327.0
PSMC2	-6765.0	4648.0
PSMC3	-4285.0	3386.0
PSMC4	-6423.0	7920.0
PSMC5	-4831.0	1120.0
PSMC6	-6851.0	8666.0
PSMD1	-6497.0	8619.0
PSMD10	-1613.0	2576.0
PSMD11	-6873.0	5201.0
PSMD12	-6149.0	8628.0
PSMD13	1898.0	5044.0
PSMD14	-6080.0	8262.0
PSMD2	-6702.0	-3836.0
PSMD3	-2532.0	-3242.0
PSMD4	-5648.0	4994.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
PSMD7	-6943.0	7625.0
PSMD8	1978.0	7546.0
PSMD9	7707.5	-894.5
PSME1	2907.0	5905.0
PSME2	1270.0	-4595.0
PSME3	752.0	7366.0
PSME4	-6830.0	8511.0
PSMF1	5087.0	4771.0
PSPN	-1715.0	-1537.0
PTAFR	-5062.0	6031.0
PTGS2	-2970.0	5783.0
PTK2	2264.0	6997.0
PTK2B	-5352.0	-3230.0
PTPN1	6946.0	3039.0
PTPN11	-3946.0	6142.0
PTPN12	-2782.0	8454.0
PTPN13	-3702.0	-4340.0
PTPN14	5809.0	5132.0
PTPN18	5824.0	-2434.0
PTPN2	-3709.0	8030.0
PTPN23	3670.0	-5769.0
PTPN3	4719.0	-4814.0
PTPN4	-2725.0	7586.0
PTPN5	-1513.0	-1213.0
PTPN6	-1098.0	2140.0
PTPN7	-1757.0	-3829.0
PTPN9	2971.0	3715.0
PTPRA	-5907.0	5079.0
PTPRZ1	3101.0	1373.0
RAE1	3041.0	-1934.0
RAF1	-6377.0	2465.0
RAG2	-807.0	3988.0
RALA	-5149.0	6748.0
RALGDS	-3350.5	-786.5
RANBP2	-4575.0	8132.0
RANBP9	-2687.0	7835.0
RAP1A	-6787.0	8805.0
RAP1B	942.0	8759.0
RAPGEF1	3892.0	3396.0
RAPGEF2	-6311.0	7475.0
RASA1	-5274.0	8011.0
RASA2	-4929.0	8291.0
RASA3	7998.0	3778.0
RASA4	507.0	-1620.0
RASAL1	3329.0	3061.0
RASAL2	-3279.0	3861.0
RASAL3	516.0	-3980.0
RASGEF1A	777.0	-1099.0
RASGRF1	-4627.0	-3572.0
RASGRF2	5156.0	1667.0
RASGRP1	-370.0	-2734.0
RASGRP3	-6128.0	7243.0
RASGRP4	-3063.0	1538.0
RBX1	-391.0	3201.0
RCE1	-2692.0	59.0
RELA	2579.0	-2368.0
RELB	4814.0	1355.0
RET	-3959.0	186.0
RGL1	-6436.0	-5685.0
RGL2	-4348.0	-6453.0
RGL3	7971.0	-6613.0
RHOU	-961.0	5238.0
RIPK2	5953.0	6306.0
RNASEL	7516.0	2800.0
RORA	-3317.0	3869.0
RORC	4429.0	-1569.0
RPS27A	-133.0	-1807.0
RPS6KA1	7703.0	4452.0
RPS6KA2	7237.0	-2956.0
RPS6KA3	-6111.0	8270.0
RPS6KA5	2516.0	-3206.0
RSAD2	-4497.0	4570.0
S100B	1781.0	-995.0
S1PR1	4311.0	7637.0
SAMHD1	1852.0	601.0
SDC1	6076.0	6227.0
SEC13	-1432.0	3604.0
SEH1L	2204.0	6910.0
SH2B1	5228.0	-6017.0
SHC1	568.0	1962.0
SHC3	-3555.0	-3601.0
SHOC2	-5120.0	8378.0
SIGIRR	-826.0	-4627.0
SKP1	-6803.0	8394.0
SMAD3	-1639.0	-2520.0
SMARCA4	-2170.0	4097.0
SNRPA1	4691.0	-2581.0
SOCS1	-253.0	-5520.0
SOCS2	4529.0	3280.0
SOCS3	4231.0	7185.0
SOCS5	1959.0	-4114.0
SOD1	-7054.0	2583.0
SOD2	-1635.0	4013.0
SOS1	-6566.0	7698.0
SOS2	-4341.0	7073.0
SPRED1	-6354.0	8554.0
SPRED2	-1328.0	-5582.0
SPRED3	3740.0	3539.0
SPTA1	-2878.0	4811.0
SPTAN1	7051.0	7359.0
SPTB	7834.0	-4096.0
SPTBN1	4136.0	7630.0
SPTBN2	7922.0	-2952.0
SPTBN5	4733.0	-1695.0
SQSTM1	-5419.0	2021.0
SRC	-2657.0	-1643.0
STAT1	-3464.0	-4440.0
STAT2	4437.0	-4922.0
STAT3	8126.0	4982.0
STAT4	-3850.0	4337.0
STAT5A	2714.0	-3795.0
STAT5B	4664.0	-4634.0
STAT6	-6946.0	2330.0
STX1A	2774.0	-2559.0
STX3	7132.0	3726.0
STX4	-3184.0	-4491.0
STXBP2	6798.0	725.0
SUMO1	-4690.0	8345.0
SYK	-6921.0	4480.0
SYNGAP1	3589.0	-4277.0
TAB1	7839.0	-5339.0
TAB2	-7040.0	7307.0
TAB3	3966.0	5424.0
TALDO1	-5386.0	449.0
TBK1	-5003.0	4897.0
TCP1	-6476.0	7694.0
TEC	-5516.0	6783.0
TEK	-2265.0	8575.0
TGFA	4979.0	2380.0
TGFB1	-1851.0	6152.0
THEM4	-3393.0	6155.0
TIMP1	-2454.0	3444.0
TLN1	-2076.0	-2832.0
TLR9	-3935.5	846.5
TNF	-2778.0	4883.0
TNFRSF11A	-6810.0	1873.0
TNFRSF11B	-1888.0	3637.0
TNFRSF12A	-4122.0	5462.0
TNFRSF13B	-3048.0	2198.0
TNFRSF13C	-2808.0	296.0
TNFRSF14	872.0	-1648.0
TNFRSF18	3888.0	-4305.0
TNFRSF1A	6733.0	6743.0
TNFRSF1B	-5427.0	939.0
TNFRSF25	6077.0	-6289.0
TNFRSF4	659.0	-624.0
TNFRSF9	4643.0	-1238.0
TNFSF12	6437.0	-3169.0
TNFSF13	2168.0	1972.0
TNFSF13B	5298.0	3905.0
TNFSF14	-1855.0	436.0
TNFSF15	-5351.0	-1629.0
TNFSF8	1617.0	2588.0
TNFSF9	154.0	2460.0
TNIP2	7153.0	-6672.0
TOLLIP	5721.0	3964.0
TP53	2557.0	-3561.0
TPR	-4239.0	8611.0
TRAF2	3405.0	-3806.0
TRAF3	-6416.0	5442.0
TRAF6	1082.0	6626.0
TRIB3	3661.0	-614.0
TRIM10	-3642.0	4159.0
TRIM14	-363.0	-4547.0
TRIM17	-1955.0	-5357.0
TRIM2	-1014.5	6967.5
TRIM21	344.0	-452.0
TRIM22	773.0	258.0
TRIM25	-5042.0	-3205.0
TRIM26	1446.0	5190.0
TRIM3	7179.0	-6505.0
TRIM34	-1848.5	-348.5
TRIM35	-6390.0	-3932.0
TRIM45	4625.0	-1893.0
TRIM46	6828.0	-2982.0
TRIM5	-7035.5	6679.5
TRIM6	466.0	3154.0
TRIM62	6914.0	-31.0
TRIM68	2033.0	1605.0
TRIM8	-6708.0	-1824.0
TWIST1	2436.0	2787.0
TXLNA	1173.0	-4792.0
TYK2	3318.0	-6265.0
UBA3	-3218.0	8194.0
UBA52	7488.0	-4269.0
UBA7	-3088.0	-3909.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
UBE2E1	-6831.0	8405.0
UBE2L6	809.0	5322.0
UBE2M	3424.0	2257.0
USP18	-5163.5	-2484.5
USP41	-5163.5	-2484.5
VAMP2	8086.5	-3275.5
VAV1	-4395.0	5076.0
VCAM1	-4983.0	4280.0
VCL	-4796.0	7947.0
VEGFA	-4619.0	-5156.0
VIM	5500.0	7940.0
VRK3	-4442.0	-4059.0
VWF	7704.0	-1950.0
WDR83	623.0	-5865.0
XAF1	-6155.0	1910.0
YES1	-120.0	7265.0
YWHAB	-4723.0	8579.0
YWHAZ	-5614.0	8512.0
ZDHHC9	-2745.0	-1163.0
ZEB1	1347.0	8478.0

---

---

Hh mutants that don't undergo autocatalytic processing are degraded by ERAD

Hh mutants that don't undergo autocatalytic processing are degraded by ERAD

metric	value
setSize	55
pMANOVA	1.92e-08
p.adjustMANOVA	5.61e-07
s.dist	0.506
s.diabetes	-0.424
s.mitoG	0.275
p.diabetes	5.17e-08
p.mitoG	0.000426

Top 20 genes

Gene	diabetes	mitoG
PSMC6	-6851.0	8666.0
UBB	-7104.0	8341.0
PSME4	-6830.0	8511.0
PSMD1	-6497.0	8619.0
SEL1L	-7264.0	7670.0
PSMD12	-6149.0	8628.0
PSMD7	-6943.0	7625.0
PSMA1	-6705.0	7838.0
UBC	-6013.0	8514.0
PSMC4	-6423.0	7920.0
PSMD14	-6080.0	8262.0
DERL2	-7153.0	6854.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
VCP	-7069.0	5449.0
PSMD11	-6873.0	5201.0
PSMA2	-5464.5	6058.5
ERLEC1	-3854.0	8504.0
PSMC2	-6765.0	4648.0
PSMB1	-5281.0	5936.0

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
DERL2	-7153.0	6854.0
ERLEC1	-3854.0	8504.0
OS9	-5615.0	3279.0
PSMA1	-6705.0	7838.0
PSMA2	-5464.5	6058.5
PSMA3	-3145.0	7801.0
PSMA4	-6074.0	4688.0
PSMA5	-6660.0	4497.0
PSMA6	-1954.0	8445.0
PSMA7	1612.0	7052.0
PSMA8	649.0	-4004.0
PSMB1	-5281.0	5936.0
PSMB10	3752.0	-908.0
PSMB11	1977.0	-5501.0
PSMB2	1472.0	-4144.0
PSMB3	-3388.0	5539.0
PSMB4	-4941.0	-5852.0
PSMB5	-1638.0	-2409.0
PSMB6	1806.0	-1845.0
PSMB7	-4628.0	-657.0
PSMB8	1080.0	-3793.0
PSMB9	5987.0	-4708.0
PSMC1	-1312.0	4327.0
PSMC2	-6765.0	4648.0
PSMC3	-4285.0	3386.0
PSMC4	-6423.0	7920.0
PSMC5	-4831.0	1120.0
PSMC6	-6851.0	8666.0
PSMD1	-6497.0	8619.0
PSMD10	-1613.0	2576.0
PSMD11	-6873.0	5201.0
PSMD12	-6149.0	8628.0
PSMD13	1898.0	5044.0
PSMD14	-6080.0	8262.0
PSMD2	-6702.0	-3836.0
PSMD3	-2532.0	-3242.0
PSMD4	-5648.0	4994.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
PSMD7	-6943.0	7625.0
PSMD8	1978.0	7546.0
PSMD9	7707.5	-894.5
PSME1	2907.0	5905.0
PSME2	1270.0	-4595.0
PSME3	752.0	7366.0
PSME4	-6830.0	8511.0
PSMF1	5087.0	4771.0
RPS27A	-133.0	-1807.0
SEL1L	-7264.0	7670.0
SHH	-4143.0	-5003.0
SYVN1	-7005.0	-3045.0
UBA52	7488.0	-4269.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
VCP	-7069.0	5449.0

---

---

Viral mRNA Translation

Viral mRNA Translation

metric	value
setSize	56
pMANOVA	2.25e-08
p.adjustMANOVA	6.45e-07
s.dist	0.407
s.diabetes	0.311
s.mitoG	0.263
p.diabetes	5.77e-05
p.mitoG	0.000653

Top 20 genes

Gene	diabetes	mitoG
RPL35	5949	8834
FAU	6809	7710
RPS15	7253	6174
RPS17	5667	7685
RPS25	4261	8455
RPL28	6714	4753
RPL26	3650	8722
RPL38	5601	5675
RPL19	4654	6782
RPS2	7322	4216
RPS8	3874	7646
RPS5	3848	7515
RPL32	2989	8728
RPL4	2582	8471
RPS4X	2522	7391
RPS14	4070	4443
RPL30	4372	3664
RPLP2	3550	3555
RPL29	2613	4628
RPS3	2340	4381

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
DNAJC3	-7149	8179
FAU	6809	7710
GRSF1	4054	-1610
RPL11	5748	1403
RPL12	6107	-5604
RPL13	5686	-3760
RPL14	5110	-1875
RPL18	2523	-625
RPL18A	4545	-3218
RPL19	4654	6782
RPL21	-1686	8463
RPL22	2365	459
RPL22L1	-5123	-6294
RPL23	-205	4253
RPL24	-409	6813
RPL26	3650	8722
RPL28	6714	4753
RPL29	2613	4628
RPL3	5378	1155
RPL30	4372	3664
RPL31	6732	-1507
RPL32	2989	8728
RPL34	661	7140
RPL35	5949	8834
RPL35A	-1509	6565
RPL36	7543	-2424
RPL36A	-5983	4837
RPL36AL	1793	-2074
RPL37	2109	-667
RPL38	5601	5675
RPL3L	-5986	4937
RPL4	2582	8471
RPL6	572	7594
RPL7	-5186	8598
RPL8	3526	820
RPLP2	3550	3555
RPS13	7174	315
RPS14	4070	4443
RPS15	7253	6174
RPS16	6244	1119
RPS17	5667	7685
RPS18	4253	-526
RPS19	6565	-1215
RPS2	7322	4216
RPS21	7111	-6494
RPS25	4261	8455
RPS27A	-133	-1807
RPS28	7208	-396
RPS3	2340	4381
RPS3A	-3115	8824
RPS4X	2522	7391
RPS5	3848	7515
RPS6	-1700	8603
RPS8	3874	7646
RPS9	-1719	-2555
UBA52	7488	-4269

---

---

Antigen processing-Cross presentation

Antigen processing-Cross presentation

metric	value
setSize	91
pMANOVA	2.3e-08
p.adjustMANOVA	6.45e-07
s.dist	0.394
s.diabetes	-0.316
s.mitoG	0.236
p.diabetes	1.96e-07
p.mitoG	0.000103

Top 20 genes

Gene	diabetes	mitoG
PSMC6	-6851	8666
UBB	-7104	8341
PSME4	-6830	8511
PDIA3	-7283	7821
PSMD1	-6497	8619
PSMD12	-6149	8628
PSMD7	-6943	7625
PSMA1	-6705	7838
SNAP23	-6477	8059
UBC	-6013	8514
PSMC4	-6423	7920
PSMD14	-6080	8262
CTSS	-5861	7572
PSMD5	-6156	7150
CD36	-7328	6006
CALR	-7105	5809
MRC1	-5573	7131
PSMD6	-6385	6157
PSMD11	-6873	5201
TLR4	-4128	8470

Click HERE to show all gene set members

All member genes

	diabetes	mitoG
B2M	5339.0	4978.0
BTK	-5279.0	5486.0
CALR	-7105.0	5809.0
CD14	4081.0	6994.0
CD36	-7328.0	6006.0
CHUK	-3701.0	8556.0
CTSS	-5861.0	7572.0
CYBA	-4719.0	-4200.0
CYBB	-5520.0	5307.0
FCGR1A	-5675.5	4265.5
FCGR1B	-5675.5	4265.5
HLA-E	3698.5	-6121.5
HLA-G	3698.5	-6121.5
IKBKB	-1785.0	-5829.0
IKBKG	3700.0	-677.0
ITGAV	8155.0	2693.0
ITGB5	7359.0	1316.0
LNPEP	4116.0	7467.0
LY96	-4879.0	364.0
MRC1	-5573.0	7131.0
MRC2	1541.0	7216.0
MYD88	-5933.0	3612.0
NCF1	3710.0	-659.0
NCF2	-1972.0	-3232.0
NCF4	-5987.0	5579.0
PDIA3	-7283.0	7821.0
PSMA1	-6705.0	7838.0
PSMA2	-5464.5	6058.5
PSMA3	-3145.0	7801.0
PSMA4	-6074.0	4688.0
PSMA5	-6660.0	4497.0
PSMA6	-1954.0	8445.0
PSMA7	1612.0	7052.0
PSMA8	649.0	-4004.0
PSMB1	-5281.0	5936.0
PSMB10	3752.0	-908.0
PSMB11	1977.0	-5501.0
PSMB2	1472.0	-4144.0
PSMB3	-3388.0	5539.0
PSMB4	-4941.0	-5852.0
PSMB5	-1638.0	-2409.0
PSMB6	1806.0	-1845.0
PSMB7	-4628.0	-657.0
PSMB8	1080.0	-3793.0
PSMB9	5987.0	-4708.0
PSMC1	-1312.0	4327.0
PSMC2	-6765.0	4648.0
PSMC3	-4285.0	3386.0
PSMC4	-6423.0	7920.0
PSMC5	-4831.0	1120.0
PSMC6	-6851.0	8666.0
PSMD1	-6497.0	8619.0
PSMD10	-1613.0	2576.0
PSMD11	-6873.0	5201.0
PSMD12	-6149.0	8628.0
PSMD13	1898.0	5044.0
PSMD14	-6080.0	8262.0
PSMD2	-6702.0	-3836.0
PSMD3	-2532.0	-3242.0
PSMD4	-5648.0	4994.0
PSMD5	-6156.0	7150.0
PSMD6	-6385.0	6157.0
PSMD7	-6943.0	7625.0
PSMD8	1978.0	7546.0
PSMD9	7707.5	-894.5
PSME1	2907.0	5905.0
PSME2	1270.0	-4595.0
PSME3	752.0	7366.0
PSME4	-6830.0	8511.0
PSMF1	5087.0	4771.0
RPS27A	-133.0	-1807.0
SEC22B	-4623.0	5601.0
SEC61A1	-6475.0	-2203.0
SEC61A2	-3708.0	-6590.0
SEC61B	-6411.0	-260.0
SEC61G	-2855.0	8720.0
SNAP23	-6477.0	8059.0
STX4	-3184.0	-4491.0
TAP1	5427.0	-6060.0
TAP2	5211.5	-5555.5
TAPBP	6125.0	-2067.0
TIRAP	-3143.0	6369.0
TLR1	-3224.0	560.0
TLR2	5407.0	5188.0
TLR4	-4128.0	8470.0
TLR6	-4778.0	7142.0
UBA52	7488.0	-4269.0
UBB	-7104.0	8341.0
UBC	-6013.0	8514.0
VAMP3	1693.0	5955.0
VAMP8	-3005.0	5301.0

---

---

Here is the session info with all the versions of packages used.

sessionInfo()

## R version 4.0.2 (2020-06-22)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 18.04.5 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.7.1
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.7.1
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.1.0               GGally_2.0.0               
##  [3] beeswarm_0.2.3              gtools_3.8.2               
##  [5] echarts4r_0.3.2             biomaRt_2.44.1             
##  [7] R.utils_2.10.1              R.oo_1.24.0                
##  [9] R.methodsS3_1.8.1           mitch_1.0.8                
## [11] eulerr_6.1.0                gplots_3.1.0               
## [13] DESeq2_1.28.1               SummarizedExperiment_1.18.2
## [15] DelayedArray_0.14.1         matrixStats_0.57.0         
## [17] Biobase_2.48.0              GenomicRanges_1.40.0       
## [19] GenomeInfoDb_1.24.2         IRanges_2.22.2             
## [21] S4Vectors_0.26.1            BiocGenerics_0.34.0        
## [23] reshape2_1.4.4              forcats_0.5.0              
## [25] stringr_1.4.0               dplyr_1.0.2                
## [27] purrr_0.3.4                 readr_1.4.0                
## [29] tidyr_1.1.2                 tibble_3.0.3               
## [31] ggplot2_3.3.2               tidyverse_1.3.0            
## 
## loaded via a namespace (and not attached):
##   [1] colorspace_1.4-1       ellipsis_0.3.1         rprojroot_1.3-2       
##   [4] XVector_0.28.0         fs_1.5.0               rstudioapi_0.11       
##   [7] farver_2.0.3           bit64_4.0.5            AnnotationDbi_1.50.3  
##  [10] fansi_0.4.1            lubridate_1.7.9        xml2_1.3.2            
##  [13] splines_4.0.2          geneplotter_1.66.0     knitr_1.30            
##  [16] polyclip_1.10-0        jsonlite_1.7.1         broom_0.7.1           
##  [19] annotate_1.66.0        dbplyr_1.4.4           shiny_1.5.0           
##  [22] compiler_4.0.2         httr_1.4.2             backports_1.1.10      
##  [25] assertthat_0.2.1       Matrix_1.2-18          fastmap_1.0.1         
##  [28] cli_2.0.2              later_1.1.0.1          prettyunits_1.1.1     
##  [31] htmltools_0.5.0        tools_4.0.2            gtable_0.3.0          
##  [34] glue_1.4.2             GenomeInfoDbData_1.2.3 rappdirs_0.3.1        
##  [37] Rcpp_1.0.5             cellranger_1.1.0       vctrs_0.3.4           
##  [40] polylabelr_0.2.0       xfun_0.18              testthat_2.3.2        
##  [43] rvest_0.3.6            mime_0.9               lifecycle_0.2.0       
##  [46] XML_3.99-0.5           zlibbioc_1.34.0        MASS_7.3-53           
##  [49] scales_1.1.1           hms_0.5.3              promises_1.1.1        
##  [52] RColorBrewer_1.1-2     curl_4.3               yaml_2.2.1            
##  [55] memoise_1.1.0          gridExtra_2.3          reshape_0.8.8         
##  [58] stringi_1.5.3          RSQLite_2.2.1          highr_0.8             
##  [61] genefilter_1.70.0      desc_1.2.0             caTools_1.18.0        
##  [64] BiocParallel_1.22.0    rlang_0.4.7            pkgconfig_2.0.3       
##  [67] bitops_1.0-6           evaluate_0.14          lattice_0.20-41       
##  [70] labeling_0.3           htmlwidgets_1.5.2      bit_4.0.4             
##  [73] tidyselect_1.1.0       plyr_1.8.6             magrittr_1.5          
##  [76] R6_2.4.1               generics_0.0.2         DBI_1.1.0             
##  [79] pillar_1.4.6           haven_2.3.1            withr_2.3.0           
##  [82] survival_3.2-7         RCurl_1.98-1.2         modelr_0.1.8          
##  [85] crayon_1.3.4           KernSmooth_2.23-17     BiocFileCache_1.12.1  
##  [88] rmarkdown_2.4          progress_1.2.2         locfit_1.5-9.4        
##  [91] grid_4.0.2             readxl_1.3.1           blob_1.2.1            
##  [94] reprex_0.3.0           digest_0.6.25          pbmcapply_1.5.0       
##  [97] xtable_1.8-4           httpuv_1.5.4           openssl_1.4.3         
## [100] munsell_0.5.0          askpass_1.1

END of report