Abstract

   Aging is correlated with several complex diseases, including type 2
   diabetes, neurodegeneration diseases, and cancer. Identifying the
   nature of this correlation and treatment of age-related diseases has
   been a major subject of both modern and traditional medicine.
   Traditional Persian Medicine (TPM) embodies many prescriptions for the
   treatment of ARDs. Given that autophagy plays a critical role in
   antiaging processes, the present study aimed to examine whether the
   documented effect of plants used in TPM might be relevant to the
   induction of autophagy? To this end, the TPM-based medicinal herbs used
   in the treatment of the ARDs were identified from modern and
   traditional references. The known phytochemicals of these plants were