Here's a breakdown of the pathway enrichment analysis details from the provided text, formatted for a table: | **Question** | **Answer** | | :--------------------------------------------- | :----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | 1. What tool was used for pathway enrichment analysis? | GSEA (Gene Set Enrichment Analysis) | | 2. Was a tool version number provided? | Not described | | 3. What gene set library was queried? | Not explicitly stated which specific library within GSEA was used, but they mention categories like ‘apoptosis’, ‘chemosensory response’ etc. which suggests custom/defined categories *in addition* to standard libraries, though which standard library they may have also used is not stated. | | 4. Was a background gene list defined? | Yes, the background gene list was defined as all coding genes (n = 14,626) used for comparison. | | 5. What statistical test was used for enrichment analysis? | Binomial probability distributions and hypergeometric tests were used. | | 6. Was false discovery rate correction used? | Yes, Benjamini-Hochberg False Discovery Rate (FDR) correction was used with an alpha value of 0.01. |