Here's a breakdown of the pathway enrichment analysis details based on the provided text, formatted for a table: | Question | Answer | |----------------------------------------------|----------------------------------------------------------------------------------------------------| | 1. What tool was used for pathway enrichment analysis? | Not described. The article mentions “pathway analysis” but doesn’t specify the tool used. | | 2. Was a tool version number provided? | Not described. | | 3. What gene set library was queried? | Not described. The article mentions pathways are enriched, but does not specify the library used. | | 4. Was a background gene list defined? | Not described. | | 5. What statistical test was used? | Not described. | | 6. Was false discovery rate correction used? | Yes. The text states “false discovery rate correction was used to control the number of false positives…”. | **Important Note:** The article is surprisingly sparse on details regarding the *methods* used for pathway enrichment. It *states* that pathway analysis was performed and that FDR correction was applied, but crucial information about the specific tools, parameters, and background gene lists used is absent. This is a limitation of the article in terms of reproducibility and transparency.