Here's a breakdown of the pathway enrichment analysis methods described in the provided text, formatted for a table as requested. **1. What tool was used for pathway enrichment analysis?** DAVID (Database for Annotation, Visualization and Integrated Discovery) **2. Was a tool version number provided?** Yes, the authors provided the version number: DAVID web server ([140]Huang da et al., 2009). **3. What gene set library was queried (eg: GO, KEGG, Reactome or other)?** Both GO (Gene Ontology) and KEGG (Kyoto Encyclopedia of Genes and Genomes) were used. **4. Was a background gene list defined for pathway enrichment analysis?** Not described. The text does not explicitly state whether a background gene list was used or how it was defined. **5. What statistical test was used for enrichment analysis?** Not described. The text mentions the use of DAVID but does not specify the particular statistical test employed for the enrichment analysis within the tool. **6. Was false discovery rate correction used to control the number of false positives in the pathway enrichment analysis?** Not described. The methods section does not mention whether or not false discovery rate (FDR) correction was applied to the results. **Table Summary:** | Question | Answer | |---|---| | 1. Tool Used | DAVID | | 2. Tool Version | Yes, ([140]Huang da et al., 2009) | | 3. Gene Set Library | GO & KEGG | | 4. Background Gene List Defined? | Not described | | 5. Statistical Test Used | Not described | | 6. FDR Correction Used? | Not described |