Here are the answers to the questions: 1. What tool was used for pathway enrichment analysis? The tool used for pathway enrichment analysis is DAVID web server. 2. Was a tool version number provided? No, the authors did not provide a version number for the DAVID web server. 3. What gene set library was queried (eg: GO, KEGG, Reactome or other)? The authors queried both GO and KEGG pathway libraries. 4. Was a background gene list defined for pathway enrichment analysis? Not described. The authors did not provide information on whether a background gene list was defined. 5. What statistical test was used for enrichment analysis? Not described. The authors did not specify the statistical test used for enrichment analysis in the DAVID web server. 6. Was false discovery rate correction used to control the number of false positives in the pathway enrichment analysis? Not described. The authors did not mention whether false discovery rate correction was used to control the number of false positives.