Based on the information provided from the article, here is how the pathway enrichment analysis appears to be conducted: 1. **Tool Used for Pathway Enrichment Analysis:** - The tools mentioned include GO (Gene Ontology) and KEGG (Kyoto Encyclopedia of Genes and Genomes) for pathway enrichment analysis. 2. **Tool Version Number Provided:** - Not described in the article. 3. **Gene Set Library Queried:** - Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG). 4. **Background Gene List Defined:** - Not explicitly described in the article, but typically this would involve using all genes represented on the microarray platform or a similar comprehensive list relevant to the study. 5. **Statistical Test Used for Enrichment Analysis:** - The specific statistical test used is not detailed in the provided text. Typically, such analyses might use Fisher's exact test or chi-squared tests, but this would need to be confirmed by reviewing more of the original article. 6. **False Discovery Rate Correction Used:** - Not described in the article. However, it is common practice in bioinformatics studies to apply false discovery rate (FDR) correction methods like Benjamini-Hochberg to control for multiple testing issues. This information can be collated into a table as follows: | Question | Answer | |-------------------------------------------------------------|-----------------------| | Tool Used for Pathway Enrichment Analysis | GO, KEGG | | Tool Version Number Provided | Not described | | Gene Set Library Queried | GO, KEGG | | Background Gene List Defined | Not described | | Statistical Test Used for Enrichment Analysis | Not described | | False Discovery Rate Correction Used | Not described | For precise details, it would be necessary to consult the full text of the article or supplementary materials that may provide additional specifics not covered in the excerpt.