Here's a breakdown of the pathway enrichment analysis methods used in the article, presented in a format suitable for a table: 1. **What tool was used for pathway enrichment analysis?** Ingenuity Pathway Analysis (IPA) 2. **Was a tool version number provided?** Not described 3. **What gene set library was queried (eg: GO, KEGG, Reactome or other)?** Not described (The article states pathways were recognised, but doesn't specify the database IPA used. It mentions canonical pathways, implying a curated knowledge base, but the specific library isn't stated.) 4. **Was a background gene list defined for pathway enrichment analysis?** Not described 5. **What statistical test was used for enrichment analysis?** Not described 6. **Was false discovery rate correction used to control the number of false positives in the pathway enrichment analysis?** P-values < 0.05 were considered statistically significant, suggesting a form of multiple testing correction was likely applied within IPA, though the specific method (e.g., FDR, Benjamini-Hochberg) isn’t explicitly stated.