Here is an analysis based on the provided text regarding how the pathway enrichment analysis was conducted: 1. **Tool Used for Pathway Enrichment Analysis:** Not explicitly described. The text mentions "9 online databases" and target gene prediction but does not specify which tool(s) were used specifically for pathway enrichment. 2. **Tool Version Number Provided:** No version number is provided in the text. 3. **Gene Set Library Queried:** The specific libraries are not described, but it mentions involvement of critical cancer-related biological processes and pathways like TGF-beta signaling pathway, Wnt signaling pathway, p53 pathway, p38 MAPK pathway, and mTOR signaling pathway. These suggest a broad range that might include databases like KEGG or others typically used in such analyses. 4. **Background Gene List Defined:** Not described. The text does not specify if there was a defined background gene list for the analysis. 5. **Statistical Test Used for Enrichment Analysis:** Not described. The specific statistical test(s) used are not detailed in the provided information. 6. **False Discovery Rate Correction Used:** Not explicitly mentioned. There is no indication of whether false discovery rate correction was applied to control false positives. This table summarizes the details: | Question | Answer | |----------|--------| | Tool Used for Pathway Enrichment Analysis | Not described | | Tool Version Number Provided | No version number provided | | Gene Set Library Queried | Specific libraries not described; implies use of common cancer-related pathways | | Background Gene List Defined | Not described | | Statistical Test Used for Enrichment Analysis | Not described | | False Discovery Rate Correction Used | Not explicitly mentioned | This analysis indicates that certain details about the pathway enrichment methodology were not fully disclosed in the article.