Thinking... We need to read the Methods section to find pathway enrichment analysis details. In the article, the relevant part is: "Functional and pathway enrichment analysis After acquiring the DEGs, GO enrichment analysis and KEGG pathway enrichment analysis were performed through DAVID (https://david.ncifcrf.gov/) online tool to identify functional categories of DEGs (16). GO analysis of DEGs included biological process (BP), molecular function (MF) and cell component (CC). In addition, the terms with P<0.05 were considered to indicate a statistically significant difference." Also: "Furthermore, the top 11 hub genes in the PPI network were analyzed via DAVID to examine pathway enrichment." And the "Module screening from the PPI network" includes modules identified via MCODE. For modules, they list "top 10 significant KEGG pathways of the DEGs in top 3 modules" but not sure if they used a tool; likely DAVID as well. Thus, the enrichment tool is DAVID. No version is specified. Gene set libraries: GO (Biological process, Molecular function, Cell component) and KEGG. Not other libraries. Background gene list: Not described. They just say "genes were submitted to DAVID." So answer "Not described". Statistical test: Not explicitly stated. In DAVID, typically hypergeometric test or Fisher's exact test is used. But article didn't specify. So "Not described". Multiple testing correction: They mention terms with P<0.05 considered significant. No mention of FDR or BH. So "No". Thus table with 6 columns: Tool, Version, Gene Set Libraries, Custom background, Statistical tests, Multiple testing correction. We must fill "List all tools or software packages used (e.g., DAVID, GSEA, Enrichr, etc.) that are explicitly mentioned". Only DAVID. Let's produce table. ...done thinking. | Question | Answer | |----------|--------| | **What tool was used for pathway enrichment analysis?** | DAVID (https://david.ncifcrf.gov/) | | **Were enrichment tool version(s) described?** | Not described | | **Which gene set libraries were used?** | Gene Ontology (GO: Biological Process, Molecular Function, Cellular Component) and Kyoto Encyclopedia of Genes and Genomes (KEGG) | | **Does the article describe using a custom or specific background gene list for enrichment analysis?** | Not described | | **What statistical test(s) were used in enrichment analysis?** | Not described | | **Was multiple testing correction / FDR applied to enrichment analysis?** | No (only a P < 0.05 threshold was mentioned) | ---