Here is the information regarding pathway enrichment analysis from the article: 1. **What tool was used for pathway enrichment analysis?** - The article does not specify a single tool used for pathway enrichment analysis. However, R package piano_1.16.4 was applied for KEGG enrichment analysis. 2. **Was a tool version number provided?** - Yes, version 1.16.4. 3. **What gene set library was queried (e.g., GO, KEGG, Reactome or other)?** - KEGG gene sets from MSigDB were queried. 4. **Was a background gene list defined for pathway enrichment analysis?** - Not described. 5. **What statistical test was used for enrichment analysis?** - Fisher’s exact test 6. **Was false discovery rate correction used to control the number of false positives in the pathway enrichment analysis?** - Yes, Benjamini-Hochberg correction was applied.