Here's a breakdown of the pathway enrichment analysis details as described in the provided text, formatted for a table: | **Question** | **Answer** | |---|---| | 1. What tool was used for pathway enrichment analysis? | R package | | 2. Was a tool version number provided? | Not described | | 3. What gene set library was queried (e.g., GO, KEGG, Reactome or other)? | GO and KEGG | | 4. Was a background gene list defined for pathway enrichment analysis? | Yes, “All the proteins” were used as the background. | | 5. What statistical test was used for enrichment analysis? | Fisher’s exact test | | 6. Was false discovery rate correction used to control the number of false positives in the pathway enrichment analysis? | Yes, Q-value was calculated to control the False Discovery Rate (FDR). The significance threshold was defined as FDR < 0.05. |