Here is a collation of the requested information regarding the pathway enrichment analysis from the scientific article, based on the Methods section and other relevant parts: 1. **Tool Used for Pathway Enrichment Analysis**: - The tool used was an R package named “q-value” as mentioned in the Proteome Data Analysis subsection. 2. **Tool Version Number Provided**: - No specific version number of the "q-value" tool is provided. 3. **Gene Set Library Queried**: - Libraries queried included Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG). 4. **Background Gene List Defined for Pathway Enrichment Analysis**: - The background gene list was defined using all the proteins as mentioned in the Proteome Data Analysis section. 5. **Statistical Test Used for Enrichment Analysis**: - Fisher’s exact test was used to calculate p-values during enrichment analysis. 6. **False Discovery Rate Correction Used**: - Yes, false discovery rate (FDR) correction was applied using the "q-value" package to control the number of false positives, with a significance threshold defined as FDR < 0.05. These details can be used to create a table for easier reference: | Question | Answer | |--------------------------------------------------------------------------|-----------------------------------------| | Tool Used for Pathway Enrichment Analysis | "q-value" R package | | Tool Version Number Provided | Not described | | Gene Set Library Queried | GO, KEGG | | Background Gene List Defined | All proteins used as background | | Statistical Test Used for Enrichment Analysis | Fisher’s exact test | | False Discovery Rate Correction Used | Yes (FDR < 0.05) | If you have any further questions or need additional details, feel free to ask!