Mitch Report
Antony Kaspi & Mark Ziemann
date generated: 2020-06-03
Background
Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch
Input profiles
Here is the first few lines of the input profile.
## ab d36
## 0610009B22Rik -0.30243426 0.9139299
## 0610009E02Rik 0.07205254 -0.8740584
## 0610009L18Rik -0.82607610 -0.6984798
## 0610010F05Rik 0.45523981 1.7576230
## 0610010K14Rik -0.96139367 -1.5168102
## 0610012G03Rik -0.80991370 -1.7438548Here are some metrics about the input data profile:
| Profile metrics | |
|---|---|
| num_genes_in_profile | 11874 |
| duplicated_genes_present | 0 |
| num_profile_genes_in_sets | 1196 |
| num_profile_genes_not_in_sets | 10678 |
| profile_pearson_correl | -0.09899 |
| profile_spearman_correl | -0.09995 |
Here is a plot of the input profiles. Note the dynamic ranges. 
Here is the contour plot of the profile including all detected genes. 
Input genesets
Here are some metrics about the gene sets used: GMT file of genesets: gsets/targeted_genesets.gmt
| Gene sets metrics | |
|---|---|
| num_genesets | 15 |
| num_genesets_excluded | 0 |
| num_genesets_included | 15 |
Gene sets by quadrant
Number of significant gene sets (FDR<0.05)= 14 
Interactive enrichment scatterplot
All sets with FDR<0.05. Try hovering over the points.
A heatmap of S values for top results
A plot of effect size versus significance
Significance is the -log2(p.adjustMANOVA) and effect size is the s.dist which is the hypotenuse of the s scores.
Results table
Top N= 15 gene sets
| set | setSize | pMANOVA | p.adjustMANOVA | s.dist | s.ab | s.d36 | p.ab | p.d36 |
|---|---|---|---|---|---|---|---|---|
| Activation-of-kainate-receptors-upon-glutamate-binding | 20 | 5.24e-03 | 6.04e-03 | 0.439 | 0.3390 | -0.2780 | 0.00864 | 3.14e-02 |
| Chondroitin-sulfate/dermatan-sulfate-metabolism | 40 | 3.97e-03 | 4.97e-03 | 0.319 | 0.2050 | -0.2440 | 0.02520 | 7.59e-03 |
| Platelet-degranulation | 93 | 1.03e-04 | 3.08e-04 | 0.269 | 0.1580 | -0.2180 | 0.00838 | 2.89e-04 |
| Mitochondrial-biogenesis | 71 | 9.67e-04 | 1.45e-03 | 0.268 | -0.1840 | 0.1960 | 0.00756 | 4.36e-03 |
| Response-to-elevated-platelet-cytosolic-Ca2+ | 97 | 2.34e-04 | 5.02e-04 | 0.252 | 0.1480 | -0.2030 | 0.01170 | 5.53e-04 |
| Chaperone-Mediated-Autophagy | 16 | 2.66e-01 | 2.66e-01 | 0.226 | -0.2090 | -0.0869 | 0.14900 | 5.47e-01 |
| Protein-localization | 141 | 1.46e-04 | 3.66e-04 | 0.215 | -0.1460 | 0.1580 | 0.00284 | 1.19e-03 |
| Platelet-activation,-signaling-and-aggregation | 187 | 8.29e-06 | 4.15e-05 | 0.214 | 0.0984 | -0.1900 | 0.02080 | 8.26e-06 |
| Neddylation | 201 | 2.12e-05 | 7.95e-05 | 0.199 | -0.1090 | 0.1660 | 0.00792 | 5.13e-05 |
| Antigen-processing:-Ubiquitination-&-Proteasome-degradation | 262 | 8.11e-07 | 6.08e-06 | 0.197 | -0.0748 | 0.1820 | 0.03800 | 4.29e-07 |
| Autophagy | 117 | 3.70e-03 | 4.97e-03 | 0.188 | -0.1270 | 0.1390 | 0.01780 | 9.70e-03 |
| Macroautophagy | 106 | 7.77e-03 | 8.32e-03 | 0.184 | -0.1090 | 0.1480 | 0.05200 | 8.82e-03 |
| Hemostasis | 373 | 4.84e-08 | 7.26e-07 | 0.184 | 0.0944 | -0.1570 | 0.00188 | 2.15e-07 |
| Chromatin-modifying-enzymes | 188 | 6.34e-04 | 1.06e-03 | 0.171 | -0.1110 | 0.1300 | 0.00910 | 2.21e-03 |
| Chromatin-organization | 188 | 6.34e-04 | 1.06e-03 | 0.171 | -0.1110 | 0.1300 | 0.00910 | 2.21e-03 |
Results (complete table)
Click HERE to show results for all gene sets
| set | setSize | pMANOVA | p.adjustMANOVA | s.dist | s.ab | s.d36 | p.ab | p.d36 |
|---|---|---|---|---|---|---|---|---|
| Activation-of-kainate-receptors-upon-glutamate-binding | 20 | 5.24e-03 | 6.04e-03 | 0.439 | 0.3390 | -0.2780 | 0.00864 | 3.14e-02 |
| Chondroitin-sulfate/dermatan-sulfate-metabolism | 40 | 3.97e-03 | 4.97e-03 | 0.319 | 0.2050 | -0.2440 | 0.02520 | 7.59e-03 |
| Platelet-degranulation | 93 | 1.03e-04 | 3.08e-04 | 0.269 | 0.1580 | -0.2180 | 0.00838 | 2.89e-04 |
| Mitochondrial-biogenesis | 71 | 9.67e-04 | 1.45e-03 | 0.268 | -0.1840 | 0.1960 | 0.00756 | 4.36e-03 |
| Response-to-elevated-platelet-cytosolic-Ca2+ | 97 | 2.34e-04 | 5.02e-04 | 0.252 | 0.1480 | -0.2030 | 0.01170 | 5.53e-04 |
| Chaperone-Mediated-Autophagy | 16 | 2.66e-01 | 2.66e-01 | 0.226 | -0.2090 | -0.0869 | 0.14900 | 5.47e-01 |
| Protein-localization | 141 | 1.46e-04 | 3.66e-04 | 0.215 | -0.1460 | 0.1580 | 0.00284 | 1.19e-03 |
| Platelet-activation,-signaling-and-aggregation | 187 | 8.29e-06 | 4.15e-05 | 0.214 | 0.0984 | -0.1900 | 0.02080 | 8.26e-06 |
| Neddylation | 201 | 2.12e-05 | 7.95e-05 | 0.199 | -0.1090 | 0.1660 | 0.00792 | 5.13e-05 |
| Antigen-processing:-Ubiquitination-&-Proteasome-degradation | 262 | 8.11e-07 | 6.08e-06 | 0.197 | -0.0748 | 0.1820 | 0.03800 | 4.29e-07 |
| Autophagy | 117 | 3.70e-03 | 4.97e-03 | 0.188 | -0.1270 | 0.1390 | 0.01780 | 9.70e-03 |
| Macroautophagy | 106 | 7.77e-03 | 8.32e-03 | 0.184 | -0.1090 | 0.1480 | 0.05200 | 8.82e-03 |
| Hemostasis | 373 | 4.84e-08 | 7.26e-07 | 0.184 | 0.0944 | -0.1570 | 0.00188 | 2.15e-07 |
| Chromatin-modifying-enzymes | 188 | 6.34e-04 | 1.06e-03 | 0.171 | -0.1110 | 0.1300 | 0.00910 | 2.21e-03 |
| Chromatin-organization | 188 | 6.34e-04 | 1.06e-03 | 0.171 | -0.1110 | 0.1300 | 0.00910 | 2.21e-03 |
Detailed Gene set reports
Activation-of-kainate-receptors-upon-glutamate-binding
| metric | value |
|---|---|
| setSize | 20 |
| pMANOVA | 0.00524 |
| p.adjustMANOVA | 0.00604 |
| s.dist | 0.439 |
| s.ab | 0.339 |
| s.d36 | -0.278 |
| p.ab | 0.00864 |
| p.d36 | 0.0314 |
| Gene | ab | d36 |
|---|---|---|
| Gng2 | 5782.5 | -5206 |
| Gng10 | 5579.5 | -4220 |
| Gnb1 | 3791.5 | -5197 |
| Gnb4 | 3274.5 | -5708 |
| Grik5 | 2338.5 | -4849 |
| Gngt2 | 5414.5 | -2034 |
| Ncald | 3160.5 | -3026 |
| Calm1 | 1392.5 | -5536 |
| Plcb3 | 3157.5 | -1110 |
| Dlg3 | 135.5 | -4345 |
Click HERE to show all gene set members
| ab | d36 | |
|---|---|---|
| Calm1 | 1392.5 | -5536 |
| Dlg1 | 783.5 | 3582 |
| Dlg3 | 135.5 | -4345 |
| Dlg4 | -3434.5 | -1076 |
| Gnb1 | 3791.5 | -5197 |
| Gnb2 | -5587.5 | -3631 |
| Gnb3 | -88.5 | -839 |
| Gnb4 | 3274.5 | -5708 |
| Gnb5 | 1823.5 | 3790 |
| Gng10 | 5579.5 | -4220 |
| Gng11 | -2523.5 | -1939 |
| Gng12 | 3603.5 | 954 |
| Gng2 | 5782.5 | -5206 |
| Gng5 | 1661.5 | 505 |
| Gngt2 | 5414.5 | -2034 |
| Grik5 | 2338.5 | -4849 |
| Ncald | 3160.5 | -3026 |
| Plcb1 | 2787.5 | 2077 |
| Plcb2 | 4464.5 | 3151 |
| Plcb3 | 3157.5 | -1110 |
Chondroitin-sulfate/dermatan-sulfate-metabolism
| metric | value |
|---|---|
| setSize | 40 |
| pMANOVA | 0.00397 |
| p.adjustMANOVA | 0.00497 |
| s.dist | 0.319 |
| s.ab | 0.205 |
| s.d36 | -0.244 |
| p.ab | 0.0252 |
| p.d36 | 0.00759 |
| Gene | ab | d36 |
|---|---|---|
| Sdc4 | 4437.5 | -5343 |
| B3gat2 | 4298.5 | -4643 |
| Bgn | 3222.5 | -5250 |
| Gpc3 | 4411.5 | -3630 |
| Chst11 | 2996.5 | -5123 |
| Arsb | 4253.5 | -3367 |
| Hyal1 | 5068.5 | -2362 |
| Cspg4 | 2597.5 | -4531 |
| Hexb | 4240.5 | -2476 |
| Xylt1 | 3972.5 | -2641 |
| Chpf2 | 2501.5 | -4004 |
| Gpc4 | 4027.5 | -1208 |
| Dcn | 1015.5 | -4121 |
| Sdc1 | 405.5 | -4246 |
| Ust | 1798.5 | -945 |
| Chst15 | 5646.5 | -234 |
| Csgalnact1 | 2986.5 | -361 |
| Dse | 3211.5 | -130 |
| Sdc2 | 115.5 | -1758 |
Click HERE to show all gene set members
| ab | d36 | |
|---|---|---|
| Agrn | -2020.5 | -3989 |
| Arsb | 4253.5 | -3367 |
| B3galt6 | 2353.5 | 744 |
| B3gat2 | 4298.5 | -4643 |
| B3gat3 | -5902.5 | -1390 |
| B4galt7 | -3621.5 | -1664 |
| Bgn | 3222.5 | -5250 |
| Chpf | -2436.5 | -2467 |
| Chpf2 | 2501.5 | -4004 |
| Chst11 | 2996.5 | -5123 |
| Chst12 | 1266.5 | 810 |
| Chst14 | 2607.5 | 2920 |
| Chst15 | 5646.5 | -234 |
| Chst3 | 5484.5 | 2758 |
| Chst7 | -1370.5 | -5509 |
| Chsy1 | -1293.5 | 1080 |
| Csgalnact1 | 2986.5 | -361 |
| Csgalnact2 | 2853.5 | 2628 |
| Cspg4 | 2597.5 | -4531 |
| Dcn | 1015.5 | -4121 |
| Dse | 3211.5 | -130 |
| Dsel | 4256.5 | 4920 |
| Gpc1 | -3965.5 | 3658 |
| Gpc3 | 4411.5 | -3630 |
| Gpc4 | 4027.5 | -1208 |
| Gpc6 | 1310.5 | 3513 |
| Hexa | -1661.5 | -5388 |
| Hexb | 4240.5 | -2476 |
| Hspg2 | -6070.5 | -4341 |
| Hyal1 | 5068.5 | -2362 |
| Ids | 884.5 | 1870 |
| Idua | -2544.5 | 996 |
| Sdc1 | 405.5 | -4246 |
| Sdc2 | 115.5 | -1758 |
| Sdc3 | -5229.5 | -5685 |
| Sdc4 | 4437.5 | -5343 |
| Ust | 1798.5 | -945 |
| Vcan | 1621.5 | 352 |
| Xylt1 | 3972.5 | -2641 |
| Xylt2 | -4688.5 | -604 |
Platelet-degranulation
| metric | value |
|---|---|
| setSize | 93 |
| pMANOVA | 0.000103 |
| p.adjustMANOVA | 0.000308 |
| s.dist | 0.269 |
| s.ab | 0.158 |
| s.d36 | -0.218 |
| p.ab | 0.00838 |
| p.d36 | 0.000289 |
| Gene | ab | d36 |
|---|---|---|
| Pecam1 | 5435.5 | -6005 |
| Anxa5 | 5360.5 | -5944 |
| Stxbp2 | 5568.5 | -5055 |
| Tmsb4x | 4551.5 | -4975 |
| Cfl1 | 3267.5 | -5778 |
| Endod1 | 3373.5 | -5527 |
| Tagln2 | 3069.5 | -6000 |
| Gas6 | 3951.5 | -4537 |
| Cap1 | 3084.5 | -5669 |
| Cyb5r1 | 3179.5 | -5170 |
| Tgfb1 | 2887.5 | -5464 |
| Rarres2 | 5080.5 | -3052 |
| Cd9 | 3960.5 | -3699 |
| Igf2 | 4185.5 | -3484 |
| Maged2 | 4830.5 | -2690 |
| Timp3 | 3838.5 | -3256 |
| Tex264 | 2147.5 | -4792 |
| Sparc | 1782.5 | -5058 |
| Qsox1 | 5388.5 | -1619 |
| Ecm1 | 2398.5 | -3458 |
Click HERE to show all gene set members
| ab | d36 | |
|---|---|---|
| Abcc4 | 1970.5 | -1670 |
| Actn1 | -4604.5 | -5024 |
| Actn2 | -5378.5 | 2638 |
| Actn4 | 761.5 | -5850 |
| Ahsg | 5563.5 | -1015 |
| Anxa5 | 5360.5 | -5944 |
| Aplp2 | 5669.5 | 2725 |
| Apool | -130.5 | 1786 |
| App | 1275.5 | -4045 |
| Brpf3 | 1875.5 | 1432 |
| Calm1 | 1392.5 | -5536 |
| Calu | 4293.5 | 1275 |
| Cap1 | 3084.5 | -5669 |
| Cd36 | -781.5 | 4859 |
| Cd63 | 150.5 | -5851 |
| Cd9 | 3960.5 | -3699 |
| Cdc37l1 | 1017.5 | 1851 |
| Cfl1 | 3267.5 | -5778 |
| Chid1 | -1245.5 | 573 |
| Clec3b | 1665.5 | -4649 |
| Clu | 5327.5 | -920 |
| Cyb5r1 | 3179.5 | -5170 |
| Ecm1 | 2398.5 | -3458 |
| Egf | 5376.5 | 5379 |
| Endod1 | 3373.5 | -5527 |
| F13a1 | -1455.5 | -4813 |
| Fam3c | 4.5 | 1264 |
| Fam49b | 2543.5 | -789 |
| Fermt3 | -342.5 | -4963 |
| Flna | -2651.5 | -5878 |
| Fn1 | 2667.5 | -1637 |
| Gas6 | 3951.5 | -4537 |
| Gtpbp2 | -4923.5 | -874 |
| Habp4 | 4847.5 | 2640 |
| Hspa5 | 1696.5 | 1779 |
| Igf1 | 2193.5 | 442 |
| Igf2 | 4185.5 | -3484 |
| Islr | 1153.5 | -3144 |
| Itga2b | -3203.5 | 5358 |
| Itgb3 | 3753.5 | 4308 |
| Itih4 | 945.5 | -4387 |
| Lamp2 | -2398.5 | 3694 |
| Lgals3bp | 1982.5 | -4128 |
| Lhfpl2 | -514.5 | -5504 |
| Maged2 | 4830.5 | -2690 |
| Manf | 93.5 | -2074 |
| Mmrn1 | -4562.5 | 1708 |
| Nhlrc2 | -2618.5 | 97 |
| Ola1 | -3044.5 | 2646 |
| Pcdh7 | 2816.5 | 4457 |
| Pcyox1l | 384.5 | -5683 |
| Pdgfa | 3387.5 | -2200 |
| Pdgfb | -3484.5 | -5070 |
| Pecam1 | 5435.5 | -6005 |
| Pf4 | -3306.5 | 2460 |
| Pfn1 | -5043.5 | -4955 |
| Phactr2 | 4578.5 | 5370 |
| Plek | -4203.5 | 4068 |
| Ppbp | -5362.5 | 1767 |
| Ppia | 808.5 | -4794 |
| Pros1 | 4179.5 | 4962 |
| Psap | -2543.5 | 4562 |
| Qsox1 | 5388.5 | -1619 |
| Rarres2 | 5080.5 | -3052 |
| Sccpdh | 227.5 | 922 |
| Selenop | 3557.5 | 571 |
| Serpine1 | 743.5 | 1911 |
| Serping1 | 1907.5 | 957 |
| Sod1 | -2867.5 | -2270 |
| Sparc | 1782.5 | -5058 |
| Srgn | -2390.5 | -4889 |
| Stxbp2 | 5568.5 | -5055 |
| Tagln2 | 3069.5 | -6000 |
| Tex264 | 2147.5 | -4792 |
| Tgfb1 | 2887.5 | -5464 |
| Tgfb2 | 1211.5 | 4752 |
| Tgfb3 | 3734.5 | 1657 |
| Thbs1 | -3465.5 | 845 |
| Timp3 | 3838.5 | -3256 |
| Tln1 | -1108.5 | -4050 |
| Tmsb4x | 4551.5 | -4975 |
| Tmx3 | 3789.5 | -879 |
| Tor4a | -2973.5 | -4855 |
| Ttn | -2540.5 | -1189 |
| Tuba4a | -4968.5 | -2273 |
| Vcl | 1603.5 | 3237 |
| Vegfa | -4638.5 | -5624 |
| Vegfb | -3753.5 | 1571 |
| Vegfc | -1320.5 | -4431 |
| Vegfd | 2021.5 | 1617 |
| Vti1b | -2278.5 | 280 |
| Vwf | 3593.5 | -1888 |
| Wdr1 | -5756.5 | -568 |
Mitochondrial-biogenesis
| metric | value |
|---|---|
| setSize | 71 |
| pMANOVA | 0.000967 |
| p.adjustMANOVA | 0.00145 |
| s.dist | 0.268 |
| s.ab | -0.184 |
| s.d36 | 0.196 |
| p.ab | 0.00756 |
| p.d36 | 0.00436 |
| Gene | ab | d36 |
|---|---|---|
| Mef2d | -5761.5 | 4862 |
| Rxra | -5660.5 | 4852 |
| Acss2 | -4581.5 | 5461 |
| Ppargc1b | -5838.5 | 3222 |
| Hcfc1 | -5321.5 | 3434 |
| Perm1 | -4178.5 | 4004 |
| Ppargc1a | -3032.5 | 5278 |
| Apoo | -3702.5 | 4223 |
| Gabpa | -3625.5 | 4243 |
| Sod2 | -2831.5 | 5288 |
| Ncor1 | -3731.5 | 3973 |
| Mapk14 | -2480.5 | 5583 |
| Med1 | -6049.5 | 2242 |
| Creb1 | -4202.5 | 2261 |
| Ssbp1 | -3638.5 | 2562 |
| Ncoa2 | -2612.5 | 3525 |
| Glud1 | -2341.5 | 2944 |
| Pprc1 | -4863.5 | 1408 |
| Prkab1 | -2504.5 | 2106 |
| Hspa9 | -1353.5 | 3772 |
Click HERE to show all gene set members
| ab | d36 | |
|---|---|---|
| Acss2 | -4581.5 | 5461 |
| Alas1 | -896.5 | -2406 |
| Apoo | -3702.5 | 4223 |
| Apool | -130.5 | 1786 |
| Atf2 | 4155.5 | 2027 |
| Atp5b | -2363.5 | 1955 |
| Calm1 | 1392.5 | -5536 |
| Carm1 | -1486.5 | 415 |
| Chchd3 | -831.5 | 2691 |
| Chchd6 | 4082.5 | -2751 |
| Chd9 | 4555.5 | -4876 |
| Creb1 | -4202.5 | 2261 |
| Crebbp | -4690.5 | -2773 |
| Crtc1 | -844.5 | 2852 |
| Crtc2 | 2053.5 | -3862 |
| Crtc3 | -2554.5 | -593 |
| Cycs | 3541.5 | 2316 |
| Dnajc11 | -4314.5 | -977 |
| Esrra | -4498.5 | -109 |
| Gabpa | -3625.5 | 4243 |
| Gabpb1 | 1435.5 | -4141 |
| Glud1 | -2341.5 | 2944 |
| Hcfc1 | -5321.5 | 3434 |
| Hdac3 | 1519.5 | 3701 |
| Helz2 | -3481.5 | -5417 |
| Hspa9 | -1353.5 | 3772 |
| Idh2 | -2044.5 | -2081 |
| Immt | 1085.5 | 3971 |
| Mapk11 | 18.5 | -5396 |
| Mapk12 | 5340.5 | -4911 |
| Mapk14 | -2480.5 | 5583 |
| Med1 | -6049.5 | 2242 |
| Mef2c | 539.5 | 3639 |
| Mef2d | -5761.5 | 4862 |
| mt-Atp6 | 462.5 | 5486 |
| mt-Atp8 | 634.5 | 4433 |
| Mtx1 | -469.5 | -1693 |
| Mtx2 | 203.5 | 1944 |
| Ncoa1 | 1438.5 | 1348 |
| Ncoa2 | -2612.5 | 3525 |
| Ncoa6 | -1446.5 | 1903 |
| Ncor1 | -3731.5 | 3973 |
| Nr1d1 | 1055.5 | 5440 |
| Nrf1 | 373.5 | -2244 |
| Perm1 | -4178.5 | 4004 |
| Polg2 | -1542.5 | 296 |
| Polrmt | -5725.5 | 749 |
| Ppara | 259.5 | 2956 |
| Ppargc1a | -3032.5 | 5278 |
| Ppargc1b | -5838.5 | 3222 |
| Pprc1 | -4863.5 | 1408 |
| Prkaa2 | 3048.5 | 4407 |
| Prkab1 | -2504.5 | 2106 |
| Prkab2 | -1248.5 | 3948 |
| Prkag1 | -70.5 | -1019 |
| Prkag2 | 5723.5 | -299 |
| Prkag3 | -2946.5 | -4836 |
| Rxra | -5660.5 | 4852 |
| Samm50 | -2824.5 | 1341 |
| Sirt3 | -1261.5 | -1097 |
| Sirt4 | -5407.5 | -3584 |
| Sirt5 | -1059.5 | 91 |
| Smarcd3 | 5640.5 | -3365 |
| Sod2 | -2831.5 | 5288 |
| Ssbp1 | -3638.5 | 2562 |
| Tbl1xr1 | -2360.5 | 498 |
| Tfam | 577.5 | 4208 |
| Tfb1m | -5150.5 | 321 |
| Tfb2m | 1574.5 | 3084 |
| Tgs1 | 2047.5 | -4808 |
| Tmem11 | -1300.5 | 1820 |
Response-to-elevated-platelet-cytosolic-Ca2+
| metric | value |
|---|---|
| setSize | 97 |
| pMANOVA | 0.000234 |
| p.adjustMANOVA | 0.000502 |
| s.dist | 0.252 |
| s.ab | 0.148 |
| s.d36 | -0.203 |
| p.ab | 0.0117 |
| p.d36 | 0.000553 |
| Gene | ab | d36 |
|---|---|---|
| Pecam1 | 5435.5 | -6005 |
| Anxa5 | 5360.5 | -5944 |
| Stxbp2 | 5568.5 | -5055 |
| Tmsb4x | 4551.5 | -4975 |
| Cfl1 | 3267.5 | -5778 |
| Endod1 | 3373.5 | -5527 |
| Tagln2 | 3069.5 | -6000 |
| Gas6 | 3951.5 | -4537 |
| Cap1 | 3084.5 | -5669 |
| Cyb5r1 | 3179.5 | -5170 |
| Tgfb1 | 2887.5 | -5464 |
| Rarres2 | 5080.5 | -3052 |
| Cd9 | 3960.5 | -3699 |
| Igf2 | 4185.5 | -3484 |
| Maged2 | 4830.5 | -2690 |
| Timp3 | 3838.5 | -3256 |
| Tex264 | 2147.5 | -4792 |
| Sparc | 1782.5 | -5058 |
| Qsox1 | 5388.5 | -1619 |
| Ecm1 | 2398.5 | -3458 |
Click HERE to show all gene set members
| ab | d36 | |
|---|---|---|
| Abcc4 | 1970.5 | -1670 |
| Actn1 | -4604.5 | -5024 |
| Actn2 | -5378.5 | 2638 |
| Actn4 | 761.5 | -5850 |
| Ahsg | 5563.5 | -1015 |
| Anxa5 | 5360.5 | -5944 |
| Aplp2 | 5669.5 | 2725 |
| Apool | -130.5 | 1786 |
| App | 1275.5 | -4045 |
| Brpf3 | 1875.5 | 1432 |
| Calm1 | 1392.5 | -5536 |
| Calu | 4293.5 | 1275 |
| Cap1 | 3084.5 | -5669 |
| Cd36 | -781.5 | 4859 |
| Cd63 | 150.5 | -5851 |
| Cd9 | 3960.5 | -3699 |
| Cdc37l1 | 1017.5 | 1851 |
| Cfl1 | 3267.5 | -5778 |
| Chid1 | -1245.5 | 573 |
| Clec3b | 1665.5 | -4649 |
| Clu | 5327.5 | -920 |
| Cyb5r1 | 3179.5 | -5170 |
| Ecm1 | 2398.5 | -3458 |
| Egf | 5376.5 | 5379 |
| Endod1 | 3373.5 | -5527 |
| F13a1 | -1455.5 | -4813 |
| Fam3c | 4.5 | 1264 |
| Fam49b | 2543.5 | -789 |
| Fermt3 | -342.5 | -4963 |
| Flna | -2651.5 | -5878 |
| Fn1 | 2667.5 | -1637 |
| Gas6 | 3951.5 | -4537 |
| Gtpbp2 | -4923.5 | -874 |
| Habp4 | 4847.5 | 2640 |
| Hspa5 | 1696.5 | 1779 |
| Igf1 | 2193.5 | 442 |
| Igf2 | 4185.5 | -3484 |
| Islr | 1153.5 | -3144 |
| Itga2b | -3203.5 | 5358 |
| Itgb3 | 3753.5 | 4308 |
| Itih4 | 945.5 | -4387 |
| Lamp2 | -2398.5 | 3694 |
| Lgals3bp | 1982.5 | -4128 |
| Lhfpl2 | -514.5 | -5504 |
| Maged2 | 4830.5 | -2690 |
| Manf | 93.5 | -2074 |
| Mmrn1 | -4562.5 | 1708 |
| Nhlrc2 | -2618.5 | 97 |
| Ola1 | -3044.5 | 2646 |
| Pcdh7 | 2816.5 | 4457 |
| Pcyox1l | 384.5 | -5683 |
| Pdgfa | 3387.5 | -2200 |
| Pdgfb | -3484.5 | -5070 |
| Pecam1 | 5435.5 | -6005 |
| Pf4 | -3306.5 | 2460 |
| Pfn1 | -5043.5 | -4955 |
| Phactr2 | 4578.5 | 5370 |
| Plek | -4203.5 | 4068 |
| Ppbp | -5362.5 | 1767 |
| Ppia | 808.5 | -4794 |
| Prkca | -5946.5 | 5085 |
| Prkcg | -808.5 | -2608 |
| Pros1 | 4179.5 | 4962 |
| Psap | -2543.5 | 4562 |
| Qsox1 | 5388.5 | -1619 |
| Rarres2 | 5080.5 | -3052 |
| Sccpdh | 227.5 | 922 |
| Selenop | 3557.5 | 571 |
| Serpine1 | 743.5 | 1911 |
| Serping1 | 1907.5 | 957 |
| Sod1 | -2867.5 | -2270 |
| Sparc | 1782.5 | -5058 |
| Srgn | -2390.5 | -4889 |
| Stx4a | 1559.5 | -4819 |
| Stxbp2 | 5568.5 | -5055 |
| Stxbp3 | 2651.5 | 5234 |
| Tagln2 | 3069.5 | -6000 |
| Tex264 | 2147.5 | -4792 |
| Tgfb1 | 2887.5 | -5464 |
| Tgfb2 | 1211.5 | 4752 |
| Tgfb3 | 3734.5 | 1657 |
| Thbs1 | -3465.5 | 845 |
| Timp3 | 3838.5 | -3256 |
| Tln1 | -1108.5 | -4050 |
| Tmsb4x | 4551.5 | -4975 |
| Tmx3 | 3789.5 | -879 |
| Tor4a | -2973.5 | -4855 |
| Ttn | -2540.5 | -1189 |
| Tuba4a | -4968.5 | -2273 |
| Vcl | 1603.5 | 3237 |
| Vegfa | -4638.5 | -5624 |
| Vegfb | -3753.5 | 1571 |
| Vegfc | -1320.5 | -4431 |
| Vegfd | 2021.5 | 1617 |
| Vti1b | -2278.5 | 280 |
| Vwf | 3593.5 | -1888 |
| Wdr1 | -5756.5 | -568 |
Chaperone-Mediated-Autophagy
| metric | value |
|---|---|
| setSize | 16 |
| pMANOVA | 0.266 |
| p.adjustMANOVA | 0.266 |
| s.dist | 0.226 |
| s.ab | -0.209 |
| s.d36 | -0.0869 |
| p.ab | 0.149 |
| p.d36 | 0.547 |
| Gene | ab | d36 |
|---|---|---|
| Rps27a | -4190.5 | -4207 |
| Uba52 | -2952.5 | -3903 |
| Park7 | -4463.5 | -2564 |
| Plin3 | -2361.5 | -3422 |
| Hbb-bt | -5467.5 | -1469 |
| Hspa8 | -6017.5 | -961 |
| Ubb | -2267.5 | -1407 |
| Hsp90aa1 | -668.5 | -4565 |
Click HERE to show all gene set members
| ab | d36 | |
|---|---|---|
| Arl13b | 3535.5 | 2626 |
| Eef1a1 | 5423.5 | -5451 |
| Hbb-bt | -5467.5 | -1469 |
| Hdac6 | 4562.5 | -4546 |
| Hsp90aa1 | -668.5 | -4565 |
| Hsp90ab1 | -5895.5 | 3412 |
| Hspa8 | -6017.5 | -961 |
| Ift88 | 53.5 | 5821 |
| Lamp2 | -2398.5 | 3694 |
| Park7 | -4463.5 | -2564 |
| Pcnt | -640.5 | 4412 |
| Plin2 | 1794.5 | 2930 |
| Plin3 | -2361.5 | -3422 |
| Rps27a | -4190.5 | -4207 |
| Uba52 | -2952.5 | -3903 |
| Ubb | -2267.5 | -1407 |
Protein-localization
| metric | value |
|---|---|
| setSize | 141 |
| pMANOVA | 0.000146 |
| p.adjustMANOVA | 0.000366 |
| s.dist | 0.215 |
| s.ab | -0.146 |
| s.d36 | 0.158 |
| p.ab | 0.00284 |
| p.d36 | 0.00119 |
| Gene | ab | d36 |
|---|---|---|
| Dhrs4 | -4704.5 | 5203 |
| Ube2d1 | -4742.5 | 4771 |
| Atad1 | -4528.5 | 4992 |
| Ldhd | -4240.5 | 5140 |
| Acot2 | -3528.5 | 5594 |
| Nudt7 | -3329.5 | 5773 |
| Cs | -3641.5 | 5068 |
| Abcd3 | -3869.5 | 4541 |
| Crat | -2926.5 | 5772 |
| Vdac1 | -3120.5 | 5253 |
| Pmpca | -3790.5 | 4294 |
| Bag6 | -5734.5 | 2768 |
| Mlycd | -2975.5 | 5299 |
| Idh1 | -3045.5 | 5095 |
| Ubl4a | -3177.5 | 4725 |
| Ide | -2882.5 | 5146 |
| Amacr | -2719.5 | 5193 |
| Hspd1 | -2883.5 | 4617 |
| Slc25a12 | -2380.5 | 5513 |
| Pex12 | -2684.5 | 4723 |
Click HERE to show all gene set members
| ab | d36 | |
|---|---|---|
| Abcd1 | -1583.5 | 5158 |
| Abcd2 | 3364.5 | 1731 |
| Abcd3 | -3869.5 | 4541 |
| Acbd5 | 4040.5 | 1686 |
| Aco2 | -1999.5 | 5196 |
| Acot2 | -3528.5 | 5594 |
| Acot4 | 1084.5 | -125 |
| Acot8 | -3903.5 | -1738 |
| Acox1 | 1182.5 | 5457 |
| Acox3 | 3081.5 | 2431 |
| Agps | -2340.5 | -440 |
| Aldh3a2 | -1798.5 | -4790 |
| Amacr | -2719.5 | 5193 |
| App | 1275.5 | -4045 |
| Asna1 | -2356.5 | -3178 |
| Atad1 | -4528.5 | 4992 |
| Bag6 | -5734.5 | 2768 |
| Bcs1l | -5667.5 | 905 |
| Caml | 4443.5 | -5219 |
| Cat | 95.5 | 5567 |
| Chchd10 | -3494.5 | -2742 |
| Chchd2 | -358.5 | -2264 |
| Chchd3 | -831.5 | 2691 |
| Chchd5 | 27.5 | -3398 |
| Chchd7 | 2517.5 | -212 |
| Cmc2 | 1429.5 | -1558 |
| Cmc4 | 475.5 | 1675 |
| Coa4 | -2316.5 | -1232 |
| Coa6 | 1483.5 | -2148 |
| Coq2 | -700.5 | 5682 |
| Cox19 | -1178.5 | -4251 |
| Crat | -2926.5 | 5772 |
| Crot | -2245.5 | 4979 |
| Cs | -3641.5 | 5068 |
| Cyb5a | 5328.5 | 58 |
| Cyc1 | -4106.5 | -1627 |
| Ddo | -1129.5 | 5697 |
| Decr2 | 359.5 | -2504 |
| Dhrs4 | -4704.5 | 5203 |
| Dnajc19 | -2715.5 | 330 |
| Ech1 | -4002.5 | 938 |
| Ehhadh | 2146.5 | 5711 |
| Emd | 1505.5 | -2801 |
| Ephx2 | -1020.5 | 5848 |
| Fis1 | 286.5 | -1590 |
| Fxn | -2359.5 | -1707 |
| Get4 | 4249.5 | -3115 |
| Gfer | -2693.5 | -5717 |
| Gnpat | 1173.5 | 4973 |
| Grpel1 | -629.5 | -1685 |
| Grpel2 | -4226.5 | 681 |
| Gstk1 | -1153.5 | 124 |
| Hacl1 | -2104.5 | 2166 |
| Hmgcl | -2497.5 | 1687 |
| Hmox1 | 697.5 | -442 |
| Hscb | -2296.5 | -1485 |
| Hsd17b4 | 273.5 | 4650 |
| Hspa9 | -1353.5 | 3772 |
| Hspd1 | -2883.5 | 4617 |
| Ide | -2882.5 | 5146 |
| Idh1 | -3045.5 | 5095 |
| Idh3g | -3160.5 | 3102 |
| Ldhd | -4240.5 | 5140 |
| Lonp2 | -493.5 | 5405 |
| Mlycd | -2975.5 | 5299 |
| Mpv17 | -3580.5 | -623 |
| Mtx1 | -469.5 | -1693 |
| Mtx2 | 203.5 | 1944 |
| Nos2 | -4783.5 | -5692 |
| Nudt19 | 4961.5 | 1526 |
| Nudt7 | -3329.5 | 5773 |
| Paox | -4685.5 | 1842 |
| Pecr | 1658.5 | -575 |
| Pex1 | 4455.5 | 3578 |
| Pex10 | 321.5 | 3276 |
| Pex12 | -2684.5 | 4723 |
| Pex13 | 4063.5 | 2706 |
| Pex14 | 248.5 | 1366 |
| Pex16 | -21.5 | -2988 |
| Pex19 | -523.5 | 3784 |
| Pex2 | -4600.5 | 1444 |
| Pex26 | 323.5 | 421 |
| Pex3 | -840.5 | 1474 |
| Pex5 | -5172.5 | -197 |
| Pex6 | -4277.5 | 1581 |
| Pex7 | -1753.5 | 5164 |
| Phyh | 1979.5 | 4810 |
| Pitrm1 | -389.5 | 3224 |
| Pmpca | -3790.5 | 4294 |
| Pmpcb | 1748.5 | 347 |
| Prnp | 1553.5 | -780 |
| Pxmp2 | -2201.5 | -1841 |
| Pxmp4 | -2845.5 | -198 |
| Rps27a | -4190.5 | -4207 |
| Samm50 | -2824.5 | 1341 |
| Scp2 | 5674.5 | 2752 |
| Sec61b | 4402.5 | -5302 |
| Sec61g | -4711.5 | -2153 |
| Serp1 | 3797.5 | -4254 |
| Sgta | -3523.5 | 859 |
| Slc25a12 | -2380.5 | 5513 |
| Slc25a13 | -1364.5 | 4643 |
| Slc25a17 | 4482.5 | -4979 |
| Slc25a4 | -1484.5 | -2700 |
| Stx1a | 5180.5 | -1194 |
| Stx5a | 4362.5 | -2257 |
| Taz | 92.5 | 4454 |
| Timm10 | -1565.5 | -1984 |
| Timm10b | 3235.5 | -729 |
| Timm13 | -5196.5 | -4663 |
| Timm17a | -3678.5 | 3270 |
| Timm17b | -2939.5 | -1781 |
| Timm21 | -3590.5 | -418 |
| Timm22 | -994.5 | -3944 |
| Timm23 | -2284.5 | 2143 |
| Timm44 | -2839.5 | -979 |
| Timm50 | -4217.5 | -2210 |
| Timm8a1 | -1552.5 | -1844 |
| Timm8b | -1081.5 | -781 |
| Timm9 | 886.5 | -6015 |
| Tomm20 | 506.5 | -993 |
| Tomm22 | 1419.5 | -1109 |
| Tomm40 | -5263.5 | -86 |
| Tomm5 | -3077.5 | -2029 |
| Tomm6 | -4094.5 | -1309 |
| Tomm7 | 2819.5 | -3129 |
| Tomm70a | -3762.5 | 2273 |
| Tysnd1 | -1743.5 | 497 |
| Uba52 | -2952.5 | -3903 |
| Ubb | -2267.5 | -1407 |
| Ube2d1 | -4742.5 | 4771 |
| Ube2d2a | 5601.5 | -410 |
| Ube2d3 | -1398.5 | 2087 |
| Ube2j2 | -920.5 | -2266 |
| Ubl4a | -3177.5 | 4725 |
| Usp9x | 2232.5 | 4874 |
| Vamp2 | 2802.5 | 1836 |
| Vapa | -1375.5 | 2198 |
| Vdac1 | -3120.5 | 5253 |
| Wrb | -374.5 | -798 |
| Zfand6 | -296.5 | 4130 |
Platelet-activation,-signaling-and-aggregation
| metric | value |
|---|---|
| setSize | 187 |
| pMANOVA | 8.29e-06 |
| p.adjustMANOVA | 4.15e-05 |
| s.dist | 0.214 |
| s.ab | 0.0984 |
| s.d36 | -0.19 |
| p.ab | 0.0208 |
| p.d36 | 8.26e-06 |
| Gene | ab | d36 |
|---|---|---|
| Pecam1 | 5435.5 | -6005 |
| Anxa5 | 5360.5 | -5944 |
| Gng2 | 5782.5 | -5206 |
| F2r | 5371.5 | -5362 |
| Stxbp2 | 5568.5 | -5055 |
| Prkch | 4679.5 | -5771 |
| Cdc42 | 4469.5 | -5470 |
| Gng10 | 5579.5 | -4220 |
| Tmsb4x | 4551.5 | -4975 |
| Gnb1 | 3791.5 | -5197 |
| Cfl1 | 3267.5 | -5778 |
| Gnb4 | 3274.5 | -5708 |
| Endod1 | 3373.5 | -5527 |
| Tagln2 | 3069.5 | -6000 |
| Arrb1 | 3464.5 | -5200 |
| Gas6 | 3951.5 | -4537 |
| Cap1 | 3084.5 | -5669 |
| Cyb5r1 | 3179.5 | -5170 |
| Tgfb1 | 2887.5 | -5464 |
| Src | 5217.5 | -2972 |
Click HERE to show all gene set members
| ab | d36 | |
|---|---|---|
| Aamp | -2258.5 | -4951 |
| Abcc4 | 1970.5 | -1670 |
| Abhd12 | 3748.5 | 806 |
| Abhd6 | 3805.5 | 2851 |
| Actn1 | -4604.5 | -5024 |
| Actn2 | -5378.5 | 2638 |
| Actn4 | 761.5 | -5850 |
| Ahsg | 5563.5 | -1015 |
| Akt1 | -4927.5 | -1552 |
| Anxa5 | 5360.5 | -5944 |
| Apbb1ip | -1738.5 | -4000 |
| Aplp2 | 5669.5 | 2725 |
| Apool | -130.5 | 1786 |
| App | 1275.5 | -4045 |
| Arrb1 | 3464.5 | -5200 |
| Arrb2 | 1118.5 | -3266 |
| Bcar1 | 8.5 | -2935 |
| Brpf3 | 1875.5 | 1432 |
| Calm1 | 1392.5 | -5536 |
| Calu | 4293.5 | 1275 |
| Cap1 | 3084.5 | -5669 |
| Cd36 | -781.5 | 4859 |
| Cd63 | 150.5 | -5851 |
| Cd9 | 3960.5 | -3699 |
| Cdc37l1 | 1017.5 | 1851 |
| Cdc42 | 4469.5 | -5470 |
| Cfl1 | 3267.5 | -5778 |
| Chid1 | -1245.5 | 573 |
| Clec3b | 1665.5 | -4649 |
| Clu | 5327.5 | -920 |
| Crk | 7.5 | 1367 |
| Csk | 1857.5 | 2296 |
| Cyb5r1 | 3179.5 | -5170 |
| Dagla | 4069.5 | -2639 |
| Daglb | 4662.5 | -2135 |
| Dgka | 3496.5 | -3918 |
| Dgkd | -5950.5 | -1156 |
| Dgke | 2302.5 | -2159 |
| Dgkh | -3593.5 | -5809 |
| Dgkq | -1263.5 | -4705 |
| Dgkz | 1666.5 | -4277 |
| Ecm1 | 2398.5 | -3458 |
| Egf | 5376.5 | 5379 |
| Endod1 | 3373.5 | -5527 |
| F13a1 | -1455.5 | -4813 |
| F2r | 5371.5 | -5362 |
| Fam3c | 4.5 | 1264 |
| Fam49b | 2543.5 | -789 |
| Fcer1g | -729.5 | -4428 |
| Fermt3 | -342.5 | -4963 |
| Flna | -2651.5 | -5878 |
| Fn1 | 2667.5 | -1637 |
| Fyn | -5007.5 | -5564 |
| Gas6 | 3951.5 | -4537 |
| Gna11 | -3119.5 | -3588 |
| Gna12 | 970.5 | 4107 |
| Gna13 | 47.5 | -635 |
| Gnai1 | 4876.5 | 1477 |
| Gnai2 | -2023.5 | -2736 |
| Gnai3 | 4769.5 | -6 |
| Gnaq | 425.5 | -2832 |
| Gnb1 | 3791.5 | -5197 |
| Gnb2 | -5587.5 | -3631 |
| Gnb3 | -88.5 | -839 |
| Gnb4 | 3274.5 | -5708 |
| Gnb5 | 1823.5 | 3790 |
| Gng10 | 5579.5 | -4220 |
| Gng11 | -2523.5 | -1939 |
| Gng12 | 3603.5 | 954 |
| Gng2 | 5782.5 | -5206 |
| Gng5 | 1661.5 | 505 |
| Gngt2 | 5414.5 | -2034 |
| Gp1ba | -2473.5 | 4196 |
| Grb2 | 4354.5 | 5789 |
| Gtpbp2 | -4923.5 | -874 |
| Habp4 | 4847.5 | 2640 |
| Hspa5 | 1696.5 | 1779 |
| Igf1 | 2193.5 | 442 |
| Igf2 | 4185.5 | -3484 |
| Islr | 1153.5 | -3144 |
| Itga2b | -3203.5 | 5358 |
| Itgb3 | 3753.5 | 4308 |
| Itih4 | 945.5 | -4387 |
| Itpr1 | -1288.5 | 1131 |
| Itpr2 | 5652.5 | -2558 |
| Itpr3 | 276.5 | -1493 |
| Lamp2 | -2398.5 | 3694 |
| Lgals3bp | 1982.5 | -4128 |
| Lhfpl2 | -514.5 | -5504 |
| Lyn | -5716.5 | -5053 |
| Maged2 | 4830.5 | -2690 |
| Manf | 93.5 | -2074 |
| Mapk1 | 2361.5 | 4015 |
| Mapk14 | -2480.5 | 5583 |
| Mapk3 | 435.5 | -5175 |
| Mgll | -2858.5 | -5344 |
| Mmrn1 | -4562.5 | 1708 |
| Nhlrc2 | -2618.5 | 97 |
| Ola1 | -3044.5 | 2646 |
| P2ry1 | -4280.5 | 4663 |
| Pcdh7 | 2816.5 | 4457 |
| Pcyox1l | 384.5 | -5683 |
| Pdgfa | 3387.5 | -2200 |
| Pdgfb | -3484.5 | -5070 |
| Pdpk1 | -45.5 | 1828 |
| Pdpn | 4867.5 | -233 |
| Pecam1 | 5435.5 | -6005 |
| Pf4 | -3306.5 | 2460 |
| Pfn1 | -5043.5 | -4955 |
| Phactr2 | 4578.5 | 5370 |
| Pik3ca | -75.5 | 473 |
| Pik3cb | 3253.5 | 4883 |
| Pik3cg | 60.5 | -1882 |
| Pik3r1 | -2910.5 | 4811 |
| Pik3r2 | -347.5 | 2632 |
| Pik3r3 | -407.5 | 5080 |
| Pik3r5 | -4833.5 | -833 |
| Pik3r6 | -4891.5 | -5133 |
| Pla2g4a | 5119.5 | 1798 |
| Plcg2 | -4984.5 | -2505 |
| Plek | -4203.5 | 4068 |
| Ppbp | -5362.5 | 1767 |
| Ppia | 808.5 | -4794 |
| Prkca | -5946.5 | 5085 |
| Prkcd | 215.5 | -2497 |
| Prkce | -4307.5 | 577 |
| Prkcg | -808.5 | -2608 |
| Prkch | 4679.5 | -5771 |
| Prkcq | -3480.5 | 5620 |
| Prkcz | 1484.5 | 23 |
| Pros1 | 4179.5 | 4962 |
| Psap | -2543.5 | 4562 |
| Ptk2 | -1152.5 | 2180 |
| Ptpn1 | 1809.5 | -279 |
| Ptpn11 | 1827.5 | 1935 |
| Ptpn6 | -4724.5 | -2054 |
| Qsox1 | 5388.5 | -1619 |
| Rac1 | 2298.5 | 4382 |
| Rac2 | -5517.5 | -4638 |
| Raf1 | -1990.5 | 4957 |
| Rap1a | 300.5 | -17 |
| Rap1b | 3328.5 | -3725 |
| Rapgef3 | -1405.5 | -5900 |
| Rapgef4 | -5554.5 | -1226 |
| Rarres2 | 5080.5 | -3052 |
| Rasgrp2 | -5264.5 | -4030 |
| Rhob | -4872.5 | 919 |
| Rhog | -4736.5 | -5706 |
| Sccpdh | 227.5 | 922 |
| Selenop | 3557.5 | 571 |
| Serpine1 | 743.5 | 1911 |
| Serping1 | 1907.5 | 957 |
| Shc1 | 3979.5 | -3058 |
| Sod1 | -2867.5 | -2270 |
| Sos1 | 5252.5 | 584 |
| Sparc | 1782.5 | -5058 |
| Src | 5217.5 | -2972 |
| Srgn | -2390.5 | -4889 |
| Stx4a | 1559.5 | -4819 |
| Stxbp2 | 5568.5 | -5055 |
| Stxbp3 | 2651.5 | 5234 |
| Syk | 2745.5 | -5361 |
| Tagln2 | 3069.5 | -6000 |
| Tex264 | 2147.5 | -4792 |
| Tgfb1 | 2887.5 | -5464 |
| Tgfb2 | 1211.5 | 4752 |
| Tgfb3 | 3734.5 | 1657 |
| Thbs1 | -3465.5 | 845 |
| Timp3 | 3838.5 | -3256 |
| Tln1 | -1108.5 | -4050 |
| Tmsb4x | 4551.5 | -4975 |
| Tmx3 | 3789.5 | -879 |
| Tor4a | -2973.5 | -4855 |
| Trpc3 | 517.5 | -2446 |
| Ttn | -2540.5 | -1189 |
| Tuba4a | -4968.5 | -2273 |
| Vav1 | -3902.5 | -2109 |
| Vav2 | -4195.5 | 5285 |
| Vav3 | -4031.5 | -177 |
| Vcl | 1603.5 | 3237 |
| Vegfa | -4638.5 | -5624 |
| Vegfb | -3753.5 | 1571 |
| Vegfc | -1320.5 | -4431 |
| Vegfd | 2021.5 | 1617 |
| Vti1b | -2278.5 | 280 |
| Vwf | 3593.5 | -1888 |
| Wdr1 | -5756.5 | -568 |
Neddylation
| metric | value |
|---|---|
| setSize | 201 |
| pMANOVA | 2.12e-05 |
| p.adjustMANOVA | 7.95e-05 |
| s.dist | 0.199 |
| s.ab | -0.109 |
| s.d36 | 0.166 |
| p.ab | 0.00792 |
| p.d36 | 5.13e-05 |
| Gene | ab | d36 |
|---|---|---|
| Klhl41 | -5951.5 | 5791 |
| Cul9 | -5135.5 | 5637 |
| Asb15 | -5545.5 | 4821 |
| Fbxw7 | -5133.5 | 4633 |
| Psme3 | -4440.5 | 5211 |
| Ube2d1 | -4742.5 | 4771 |
| Zbtb16 | -6061.5 | 3697 |
| Asb5 | -4064.5 | 5502 |
| Dcaf4 | -3976.5 | 5566 |
| Fem1c | -5053.5 | 4221 |
| Psme4 | -3880.5 | 5488 |
| Fem1b | -3964.5 | 4682 |
| Dcun1d2 | -4411.5 | 4096 |
| Cops7b | -3148.5 | 5694 |
| Dcaf11 | -3438.5 | 4993 |
| Dcaf5 | -5986.5 | 2796 |
| Psmd3 | -4458.5 | 3681 |
| Fbxl7 | -3915.5 | 4142 |
| Cops4 | -3518.5 | 4318 |
| Wdtc1 | -3510.5 | 4299 |
Click HERE to show all gene set members
| ab | d36 | |
|---|---|---|
| Ankrd9 | 986.5 | -806 |
| Asb1 | 1698.5 | 4893 |
| Asb10 | -3554.5 | 2295 |
| Asb11 | -5098.5 | -518 |
| Asb12 | -3863.5 | -495 |
| Asb13 | -428.5 | -3957 |
| Asb14 | -4269.5 | 3319 |
| Asb15 | -5545.5 | 4821 |
| Asb18 | 1105.5 | 1021 |
| Asb2 | -5153.5 | 2613 |
| Asb3 | 1280.5 | 3383 |
| Asb4 | 1853.5 | 2232 |
| Asb5 | -4064.5 | 5502 |
| Asb6 | 2645.5 | -2731 |
| Asb7 | 2538.5 | -3014 |
| Asb8 | -2969.5 | 3477 |
| Btbd1 | 3959.5 | 5119 |
| Btbd6 | 1040.5 | 3369 |
| Btrc | -2260.5 | 5798 |
| Cand1 | -273.5 | 2560 |
| Ccdc22 | -1597.5 | -4587 |
| Ccdc8 | 5516.5 | -3557 |
| Cish | -6028.5 | 2049 |
| Commd10 | 907.5 | -241 |
| Commd2 | 732.5 | 1776 |
| Commd3 | 1826.5 | -1334 |
| Commd4 | 2028.5 | -2733 |
| Commd5 | 3508.5 | -3070 |
| Commd6 | 2392.5 | -809 |
| Commd7 | 148.5 | -119 |
| Commd8 | 5375.5 | 1077 |
| Commd9 | 3696.5 | -2449 |
| Cops2 | -587.5 | 2611 |
| Cops3 | 3295.5 | -1435 |
| Cops4 | -3518.5 | 4318 |
| Cops5 | -2701.5 | -2099 |
| Cops6 | -2775.5 | 2084 |
| Cops7a | 598.5 | 4983 |
| Cops7b | -3148.5 | 5694 |
| Cops8 | -2217.5 | 2290 |
| Cul1 | 3128.5 | 5019 |
| Cul2 | -1103.5 | 3216 |
| Cul3 | -634.5 | 3414 |
| Cul4a | -946.5 | 2329 |
| Cul4b | 5075.5 | -71 |
| Cul5 | -1192.5 | 2382 |
| Cul7 | -1162.5 | -4112 |
| Cul9 | -5135.5 | 5637 |
| Dcaf10 | 34.5 | 3683 |
| Dcaf11 | -3438.5 | 4993 |
| Dcaf13 | 893.5 | -3151 |
| Dcaf17 | 1410.5 | -384 |
| Dcaf4 | -3976.5 | 5566 |
| Dcaf5 | -5986.5 | 2796 |
| Dcaf6 | -517.5 | 3599 |
| Dcaf7 | -5857.5 | 1942 |
| Dcun1d1 | 777.5 | 907 |
| Dcun1d2 | -4411.5 | 4096 |
| Dcun1d3 | 1695.5 | -1384 |
| Dcun1d4 | 3010.5 | 1744 |
| Dcun1d5 | -2614.5 | 2716 |
| Dda1 | 530.5 | -313 |
| Ddb1 | 615.5 | 2816 |
| Ddb2 | 3450.5 | -5602 |
| Epas1 | -3598.5 | 2954 |
| Ercc8 | 1324.5 | -2536 |
| Fbxl12 | 3604.5 | 3797 |
| Fbxl14 | 549.5 | -1615 |
| Fbxl15 | -4248.5 | -2164 |
| Fbxl16 | 3575.5 | -2999 |
| Fbxl18 | 964.5 | 724 |
| Fbxl19 | 1026.5 | 944 |
| Fbxl20 | 562.5 | -2000 |
| Fbxl22 | 628.5 | -4944 |
| Fbxl3 | 3831.5 | 1280 |
| Fbxl4 | 4340.5 | 4767 |
| Fbxl5 | 5518.5 | 5510 |
| Fbxl7 | -3915.5 | 4142 |
| Fbxl8 | 3707.5 | -290 |
| Fbxo10 | -2342.5 | 5304 |
| Fbxo11 | 5242.5 | 3610 |
| Fbxo21 | -441.5 | 5668 |
| Fbxo22 | 1453.5 | -5860 |
| Fbxo30 | -5989.5 | 2487 |
| Fbxo31 | -864.5 | 5809 |
| Fbxo32 | -2560.5 | 5160 |
| Fbxo4 | 3988.5 | 2496 |
| Fbxo40 | -5726.5 | 1670 |
| Fbxo44 | 5676.5 | 284 |
| Fbxo6 | 1069.5 | 2041 |
| Fbxo7 | -3157.5 | -1773 |
| Fbxo9 | 3451.5 | 779 |
| Fbxw11 | -815.5 | 1933 |
| Fbxw2 | 2363.5 | -398 |
| Fbxw4 | -5775.5 | 1209 |
| Fbxw5 | -2629.5 | 5250 |
| Fbxw7 | -5133.5 | 4633 |
| Fbxw8 | 3867.5 | -678 |
| Fbxw9 | -6027.5 | -5662 |
| Fem1b | -3964.5 | 4682 |
| Fem1c | -5053.5 | 4221 |
| Gan | -1528.5 | -1598 |
| Gps1 | -3596.5 | -772 |
| Hif1a | -3296.5 | 2976 |
| Kbtbd7 | -4526.5 | -1155 |
| Kctd6 | 348.5 | 2268 |
| Kctd7 | 4238.5 | 789 |
| Keap1 | -3459.5 | 1943 |
| Klhl11 | 2942.5 | 5133 |
| Klhl13 | 4891.5 | 2473 |
| Klhl2 | -2446.5 | 424 |
| Klhl20 | 3761.5 | 661 |
| Klhl21 | -2121.5 | 3422 |
| Klhl22 | -1476.5 | 3001 |
| Klhl25 | -1934.5 | -1968 |
| Klhl3 | -3104.5 | 3092 |
| Klhl41 | -5951.5 | 5791 |
| Klhl42 | -1082.5 | -866 |
| Klhl5 | 357.5 | -937 |
| Klhl9 | -931.5 | -1591 |
| Lmo7 | 1443.5 | 5514 |
| Lrrc41 | -1093.5 | -1915 |
| Nae1 | 54.5 | 3223 |
| Nedd8 | -3687.5 | -3613 |
| Neurl2 | -1880.5 | 3850 |
| Nub1 | -1997.5 | 3337 |
| Obsl1 | -1564.5 | 1063 |
| Psma1 | -3443.5 | 2810 |
| Psma2 | 65.5 | 1039 |
| Psma3 | -3576.5 | -3965 |
| Psma4 | 2014.5 | 1669 |
| Psma5 | -4425.5 | -2091 |
| Psma6 | 1101.5 | 783 |
| Psma7 | -3737.5 | -1348 |
| Psmb1 | 1352.5 | -1931 |
| Psmb10 | -124.5 | -5666 |
| Psmb2 | -4177.5 | -2748 |
| Psmb3 | -3974.5 | -2006 |
| Psmb4 | -4922.5 | -3974 |
| Psmb5 | -4543.5 | -4446 |
| Psmb6 | -4903.5 | -3935 |
| Psmb7 | -4340.5 | 477 |
| Psmb8 | -2315.5 | -3885 |
| Psmb9 | -4703.5 | -108 |
| Psmc1 | -2094.5 | -1203 |
| Psmc2 | -3960.5 | 2275 |
| Psmc3 | -1045.5 | -2312 |
| Psmc4 | -889.5 | -4569 |
| Psmc5 | -2672.5 | -3247 |
| Psmc6 | -1556.5 | 1385 |
| Psmd1 | -599.5 | 667 |
| Psmd10 | -1139.5 | 5000 |
| Psmd11 | -5204.5 | 1824 |
| Psmd12 | -937.5 | 3831 |
| Psmd13 | -2303.5 | -2879 |
| Psmd14 | -2527.5 | 2370 |
| Psmd2 | -3266.5 | 3570 |
| Psmd3 | -4458.5 | 3681 |
| Psmd4 | -1978.5 | -3805 |
| Psmd5 | 582.5 | 1 |
| Psmd6 | 1353.5 | -1526 |
| Psmd7 | -2675.5 | 379 |
| Psmd8 | 4829.5 | -23 |
| Psmd9 | 665.5 | 923 |
| Psme1 | -4810.5 | -1389 |
| Psme2b | -1033.5 | 491 |
| Psme3 | -4440.5 | 5211 |
| Psme4 | -3880.5 | 5488 |
| Psmf1 | -2056.5 | -2589 |
| Pum2 | 1240.5 | 1564 |
| Rbbp5 | -1857.5 | 4372 |
| Rbbp7 | 2413.5 | 3592 |
| Rbx1 | 1071.5 | -3541 |
| Rnf7 | -2725.5 | -499 |
| Rps27a | -4190.5 | -4207 |
| Senp8 | -1749.5 | 406 |
| Skp1a | 3485.5 | 3561 |
| Socs2 | -121.5 | -3402 |
| Socs3 | 3467.5 | 3794 |
| Socs5 | 4122.5 | 715 |
| Socs6 | -6037.5 | 1486 |
| Spsb1 | 4644.5 | 4612 |
| Spsb2 | 3204.5 | 4290 |
| Spsb3 | -525.5 | -3861 |
| Spsb4 | -2078.5 | -5303 |
| Tulp4 | 3825.5 | 55 |
| Uba3 | 3068.5 | 3078 |
| Uba52 | -2952.5 | -3903 |
| Ubb | -2267.5 | -1407 |
| Ube2d1 | -4742.5 | 4771 |
| Ube2d2a | 5601.5 | -410 |
| Ube2d3 | -1398.5 | 2087 |
| Ube2f | 1329.5 | 500 |
| Ube2m | -1944.5 | -2636 |
| Ubxn7 | 4169.5 | -1054 |
| Vhl | 1284.5 | 2318 |
| Wdr5 | -2834.5 | 754 |
| Wdtc1 | -3510.5 | 4299 |
| Wsb1 | 2376.5 | 261 |
| Wsb2 | -2224.5 | 3725 |
| Zbtb16 | -6061.5 | 3697 |
Antigen-processing:-Ubiquitination-&-Proteasome-degradation
| metric | value |
|---|---|
| setSize | 262 |
| pMANOVA | 8.11e-07 |
| p.adjustMANOVA | 6.08e-06 |
| s.dist | 0.197 |
| s.ab | -0.0748 |
| s.d36 | 0.182 |
| p.ab | 0.038 |
| p.d36 | 4.29e-07 |
| Gene | ab | d36 |
|---|---|---|
| Klhl41 | -5951.5 | 5791 |
| Det1 | -5539.5 | 5828 |
| Rnf123 | -5790.5 | 4970 |
| Ubr4 | -5983.5 | 4668 |
| Asb15 | -5545.5 | 4821 |
| Trim63 | -4991.5 | 5292 |
| Rnf144b | -5065.5 | 4809 |
| Fbxw7 | -5133.5 | 4633 |
| Psme3 | -4440.5 | 5211 |
| Ube2d1 | -4742.5 | 4771 |
| Zbtb16 | -6061.5 | 3697 |
| Asb5 | -4064.5 | 5502 |
| Uba1 | -4276.5 | 5013 |
| Psme4 | -3880.5 | 5488 |
| Npepps | -5495.5 | 3488 |
| Ubr2 | -3504.5 | 5120 |
| Psmd3 | -4458.5 | 3681 |
| Fbxl7 | -3915.5 | 4142 |
| Rnf114 | -4735.5 | 3397 |
| Ube2a | -4068.5 | 3801 |
Click HERE to show all gene set members
| ab | d36 | |
|---|---|---|
| Anapc1 | 388.5 | 4095 |
| Anapc10 | -1897.5 | -622 |
| Anapc11 | -1892.5 | -4167 |
| Anapc13 | -875.5 | -3121 |
| Anapc2 | -3082.5 | -3659 |
| Anapc4 | 4523.5 | 1722 |
| Anapc5 | 1150.5 | 537 |
| Anapc7 | -4503.5 | 1245 |
| Arel1 | 2451.5 | 5634 |
| Arih2 | 467.5 | 2210 |
| Asb1 | 1698.5 | 4893 |
| Asb10 | -3554.5 | 2295 |
| Asb11 | -5098.5 | -518 |
| Asb12 | -3863.5 | -495 |
| Asb13 | -428.5 | -3957 |
| Asb14 | -4269.5 | 3319 |
| Asb15 | -5545.5 | 4821 |
| Asb18 | 1105.5 | 1021 |
| Asb2 | -5153.5 | 2613 |
| Asb3 | 1280.5 | 3383 |
| Asb4 | 1853.5 | 2232 |
| Asb5 | -4064.5 | 5502 |
| Asb6 | 2645.5 | -2731 |
| Asb7 | 2538.5 | -3014 |
| Asb8 | -2969.5 | 3477 |
| Atg7 | -2197.5 | 1108 |
| Blmh | -2031.5 | 2786 |
| Btbd1 | 3959.5 | 5119 |
| Btbd6 | 1040.5 | 3369 |
| Btrc | -2260.5 | 5798 |
| Cblb | 5713.5 | 3769 |
| Cdc16 | -3171.5 | 4187 |
| Cdc23 | 3978.5 | 2286 |
| Cdc26 | -597.5 | 1770 |
| Cdc27 | 2837.5 | 3350 |
| Cul1 | 3128.5 | 5019 |
| Cul2 | -1103.5 | 3216 |
| Cul3 | -634.5 | 3414 |
| Cul5 | -1192.5 | 2382 |
| Cul7 | -1162.5 | -4112 |
| Det1 | -5539.5 | 5828 |
| Dtx3l | -5807.5 | 2536 |
| Dzip3 | 729.5 | 4497 |
| Fbxl12 | 3604.5 | 3797 |
| Fbxl14 | 549.5 | -1615 |
| Fbxl15 | -4248.5 | -2164 |
| Fbxl16 | 3575.5 | -2999 |
| Fbxl18 | 964.5 | 724 |
| Fbxl19 | 1026.5 | 944 |
| Fbxl20 | 562.5 | -2000 |
| Fbxl22 | 628.5 | -4944 |
| Fbxl3 | 3831.5 | 1280 |
| Fbxl4 | 4340.5 | 4767 |
| Fbxl5 | 5518.5 | 5510 |
| Fbxl7 | -3915.5 | 4142 |
| Fbxl8 | 3707.5 | -290 |
| Fbxo10 | -2342.5 | 5304 |
| Fbxo11 | 5242.5 | 3610 |
| Fbxo21 | -441.5 | 5668 |
| Fbxo22 | 1453.5 | -5860 |
| Fbxo30 | -5989.5 | 2487 |
| Fbxo31 | -864.5 | 5809 |
| Fbxo32 | -2560.5 | 5160 |
| Fbxo4 | 3988.5 | 2496 |
| Fbxo40 | -5726.5 | 1670 |
| Fbxo44 | 5676.5 | 284 |
| Fbxo6 | 1069.5 | 2041 |
| Fbxo7 | -3157.5 | -1773 |
| Fbxo9 | 3451.5 | 779 |
| Fbxw11 | -815.5 | 1933 |
| Fbxw2 | 2363.5 | -398 |
| Fbxw4 | -5775.5 | 1209 |
| Fbxw5 | -2629.5 | 5250 |
| Fbxw7 | -5133.5 | 4633 |
| Fbxw8 | 3867.5 | -678 |
| Fbxw9 | -6027.5 | -5662 |
| Fzr1 | -2533.5 | 3572 |
| Gan | -1528.5 | -1598 |
| Glmn | 4483.5 | 5364 |
| Hace1 | 2456.5 | 3049 |
| Hectd1 | -2200.5 | 3829 |
| Hectd3 | 3537.5 | -221 |
| Hecw2 | -2633.5 | -599 |
| Herc1 | 833.5 | 14 |
| Herc2 | -2192.5 | -894 |
| Herc3 | 3676.5 | 2170 |
| Herc4 | 4387.5 | 4192 |
| Herc6 | 4289.5 | -1860 |
| Huwe1 | -4626.5 | 2122 |
| Itch | 5125.5 | -1838 |
| Kbtbd7 | -4526.5 | -1155 |
| Kctd6 | 348.5 | 2268 |
| Kctd7 | 4238.5 | 789 |
| Keap1 | -3459.5 | 1943 |
| Klhl11 | 2942.5 | 5133 |
| Klhl13 | 4891.5 | 2473 |
| Klhl2 | -2446.5 | 424 |
| Klhl20 | 3761.5 | 661 |
| Klhl21 | -2121.5 | 3422 |
| Klhl22 | -1476.5 | 3001 |
| Klhl25 | -1934.5 | -1968 |
| Klhl3 | -3104.5 | 3092 |
| Klhl41 | -5951.5 | 5791 |
| Klhl42 | -1082.5 | -866 |
| Klhl5 | 357.5 | -937 |
| Klhl9 | -931.5 | -1591 |
| Lmo7 | 1443.5 | 5514 |
| Lnpep | 4457.5 | 2608 |
| Lnx1 | -1904.5 | 2456 |
| Lonrf1 | 527.5 | 5523 |
| Lrrc41 | -1093.5 | -1915 |
| Lrsam1 | 2626.5 | -933 |
| Ltn1 | -283.5 | 4676 |
| Mex3c | 2371.5 | 1587 |
| Mgrn1 | 4381.5 | 5419 |
| Mib2 | -4715.5 | -2662 |
| Mkrn1 | -5431.5 | -1947 |
| Mylip | 5357.5 | -1037 |
| Nedd4 | -3102.5 | 3825 |
| Nedd4l | 2973.5 | 1259 |
| Npepps | -5495.5 | 3488 |
| Pja1 | 4672.5 | -2600 |
| Pja2 | -792.5 | 2959 |
| Psma1 | -3443.5 | 2810 |
| Psma2 | 65.5 | 1039 |
| Psma3 | -3576.5 | -3965 |
| Psma4 | 2014.5 | 1669 |
| Psma5 | -4425.5 | -2091 |
| Psma6 | 1101.5 | 783 |
| Psma7 | -3737.5 | -1348 |
| Psmb1 | 1352.5 | -1931 |
| Psmb10 | -124.5 | -5666 |
| Psmb2 | -4177.5 | -2748 |
| Psmb3 | -3974.5 | -2006 |
| Psmb4 | -4922.5 | -3974 |
| Psmb5 | -4543.5 | -4446 |
| Psmb6 | -4903.5 | -3935 |
| Psmb7 | -4340.5 | 477 |
| Psmb8 | -2315.5 | -3885 |
| Psmb9 | -4703.5 | -108 |
| Psmc1 | -2094.5 | -1203 |
| Psmc2 | -3960.5 | 2275 |
| Psmc3 | -1045.5 | -2312 |
| Psmc4 | -889.5 | -4569 |
| Psmc5 | -2672.5 | -3247 |
| Psmc6 | -1556.5 | 1385 |
| Psmd1 | -599.5 | 667 |
| Psmd10 | -1139.5 | 5000 |
| Psmd11 | -5204.5 | 1824 |
| Psmd12 | -937.5 | 3831 |
| Psmd13 | -2303.5 | -2879 |
| Psmd14 | -2527.5 | 2370 |
| Psmd2 | -3266.5 | 3570 |
| Psmd3 | -4458.5 | 3681 |
| Psmd4 | -1978.5 | -3805 |
| Psmd5 | 582.5 | 1 |
| Psmd6 | 1353.5 | -1526 |
| Psmd7 | -2675.5 | 379 |
| Psmd8 | 4829.5 | -23 |
| Psmd9 | 665.5 | 923 |
| Psme1 | -4810.5 | -1389 |
| Psme2b | -1033.5 | 491 |
| Psme3 | -4440.5 | 5211 |
| Psme4 | -3880.5 | 5488 |
| Psmf1 | -2056.5 | -2589 |
| Rbbp6 | -906.5 | 1058 |
| Rbck1 | -5327.5 | -1324 |
| Rbx1 | 1071.5 | -3541 |
| Rchy1 | 3284.5 | 1165 |
| Rlim | 2710.5 | 2348 |
| Rnf111 | -4104.5 | 1113 |
| Rnf114 | -4735.5 | 3397 |
| Rnf115 | -4168.5 | -1214 |
| Rnf123 | -5790.5 | 4970 |
| Rnf126 | -2004.5 | -3842 |
| Rnf130 | 595.5 | -2914 |
| Rnf14 | 2720.5 | 2898 |
| Rnf144b | -5065.5 | 4809 |
| Rnf19a | 3123.5 | -1621 |
| Rnf19b | -3602.5 | 449 |
| Rnf213 | -1479.5 | -5845 |
| Rnf217 | 4959.5 | 1917 |
| Rnf220 | 4141.5 | -2246 |
| Rnf25 | 1050.5 | -3898 |
| Rnf34 | 58.5 | -20 |
| Rnf4 | 2352.5 | 896 |
| Rnf41 | 4490.5 | 3485 |
| Rnf6 | 3766.5 | 1253 |
| Rnf7 | -2725.5 | -499 |
| Rps27a | -4190.5 | -4207 |
| Sh3rf1 | -4303.5 | -305 |
| Siah2 | 4194.5 | -496 |
| Skp1a | 3485.5 | 3561 |
| Smurf1 | -131.5 | -615 |
| Smurf2 | -5014.5 | 493 |
| Socs3 | 3467.5 | 3794 |
| Spsb1 | 4644.5 | 4612 |
| Spsb2 | 3204.5 | 4290 |
| Spsb4 | -2078.5 | -5303 |
| Stub1 | -3601.5 | -3303 |
| Thop1 | -5842.5 | -5476 |
| Tpp2 | -780.5 | 5220 |
| Traf7 | 3931.5 | -5245 |
| Trim11 | 2386.5 | -56 |
| Trim21 | 4200.5 | -657 |
| Trim32 | -1235.5 | 3988 |
| Trim37 | 699.5 | 3868 |
| Trim39 | 3365.5 | -3089 |
| Trim41 | 176.5 | 3495 |
| Trim63 | -4991.5 | 5292 |
| Trip12 | 1320.5 | 2931 |
| Uba1 | -4276.5 | 5013 |
| Uba3 | 3068.5 | 3078 |
| Uba5 | 5639.5 | -4956 |
| Uba52 | -2952.5 | -3903 |
| Uba6 | 793.5 | -3414 |
| Uba7 | -3561.5 | -4129 |
| Ubac1 | -2037.5 | 5294 |
| Ubb | -2267.5 | -1407 |
| Ube2a | -4068.5 | 3801 |
| Ube2b | 1901.5 | 5258 |
| Ube2d1 | -4742.5 | 4771 |
| Ube2d2a | 5601.5 | -410 |
| Ube2d3 | -1398.5 | 2087 |
| Ube2e1 | 439.5 | -2644 |
| Ube2e2 | -1427.5 | 4376 |
| Ube2e3 | -2689.5 | 4093 |
| Ube2f | 1329.5 | 500 |
| Ube2g1 | -3202.5 | 2677 |
| Ube2g2 | -621.5 | -3155 |
| Ube2h | -490.5 | 3043 |
| Ube2j1 | -191.5 | 3231 |
| Ube2j2 | -920.5 | -2266 |
| Ube2k | -113.5 | 3738 |
| Ube2l3 | -1073.5 | 4775 |
| Ube2l6 | -5506.5 | -3683 |
| Ube2m | -1944.5 | -2636 |
| Ube2o | -5910.5 | -804 |
| Ube2q1 | 1924.5 | -4274 |
| Ube2q2 | 4687.5 | 2926 |
| Ube2r2 | -2687.5 | 4185 |
| Ube2s | -1515.5 | -2249 |
| Ube2v1 | -567.5 | -828 |
| Ube2v2 | -1547.5 | 2720 |
| Ube2w | 1656.5 | 3230 |
| Ube2z | 2458.5 | 2886 |
| Ube3a | 1116.5 | 2692 |
| Ube3b | -745.5 | 4199 |
| Ube3c | 3445.5 | 1086 |
| Ube4a | 1440.5 | 2526 |
| Ubox5 | -4155.5 | -2107 |
| Ubr1 | -1171.5 | -567 |
| Ubr2 | -3504.5 | 5120 |
| Ubr4 | -5983.5 | 4668 |
| Ufl1 | 4091.5 | 1139 |
| Unkl | -900.5 | 2945 |
| Vhl | 1284.5 | 2318 |
| Wsb1 | 2376.5 | 261 |
| Wwp1 | -470.5 | 4054 |
| Zbtb16 | -6061.5 | 3697 |
| Znrf1 | -4673.5 | -4440 |
| Znrf2 | 1402.5 | 4635 |
Autophagy
| metric | value |
|---|---|
| setSize | 117 |
| pMANOVA | 0.0037 |
| p.adjustMANOVA | 0.00497 |
| s.dist | 0.188 |
| s.ab | -0.127 |
| s.d36 | 0.139 |
| p.ab | 0.0178 |
| p.d36 | 0.0097 |
| Gene | ab | d36 |
|---|---|---|
| Atg9a | -5319.5 | 4961 |
| Vcp | -4619.5 | 5396 |
| Tsc2 | -5449.5 | 4564 |
| Pgam5 | -4296.5 | 5336 |
| Dynll2 | -4915.5 | 4603 |
| Hsp90ab1 | -5895.5 | 3412 |
| Sqstm1 | -4504.5 | 3770 |
| Vdac1 | -3120.5 | 5253 |
| Mlst8 | -3051.5 | 5337 |
| Chmp4c | -4050.5 | 3228 |
| Ulk1 | -5479.5 | 2380 |
| Atg4b | -4652.5 | 2598 |
| Rptor | -4005.5 | 2914 |
| Epas1 | -3598.5 | 2954 |
| Wipi1 | -4477.5 | 2336 |
| Atg4d | -2309.5 | 4452 |
| Ubap1 | -4066.5 | 2508 |
| Wdr45b | -5256.5 | 1826 |
| Mvb12b | -1809.5 | 5191 |
| Lamp2 | -2398.5 | 3694 |
Click HERE to show all gene set members
| ab | d36 | |
|---|---|---|
| Ambra1 | 2209.5 | 865 |
| Arl13b | 3535.5 | 2626 |
| Atg10 | 2771.5 | 245 |
| Atg101 | 5752.5 | -4595 |
| Atg12 | -348.5 | 1754 |
| Atg13 | -3298.5 | 247 |
| Atg14 | -2991.5 | 2109 |
| Atg16l1 | -2053.5 | 1151 |
| Atg3 | -3579.5 | -1582 |
| Atg4a | 4391.5 | 591 |
| Atg4b | -4652.5 | 2598 |
| Atg4c | 5467.5 | 1478 |
| Atg4d | -2309.5 | 4452 |
| Atg5 | 5122.5 | 2910 |
| Atg7 | -2197.5 | 1108 |
| Atg9a | -5319.5 | 4961 |
| Atm | 911.5 | 516 |
| Becn1 | 2652.5 | -673 |
| Chmp2a | 930.5 | -2707 |
| Chmp2b | -3820.5 | 1878 |
| Chmp3 | 4527.5 | 210 |
| Chmp4b | 4442.5 | -2976 |
| Chmp4c | -4050.5 | 3228 |
| Chmp6 | -53.5 | 3017 |
| Chmp7 | 442.5 | -2541 |
| Csnk2a1 | 966.5 | 3203 |
| Csnk2a2 | -1462.5 | -3339 |
| Csnk2b | 268.5 | -2671 |
| Dync1h1 | -5568.5 | 1394 |
| Dync1i2 | 2734.5 | -3975 |
| Dync1li1 | -2517.5 | 1393 |
| Dync1li2 | -2486.5 | 3478 |
| Dynll1 | 372.5 | -5867 |
| Dynll2 | -4915.5 | 4603 |
| Eef1a1 | 5423.5 | -5451 |
| Epas1 | -3598.5 | 2954 |
| Fundc1 | 3006.5 | 4373 |
| Gabarap | 3820.5 | 179 |
| Gabarapl1 | 3101.5 | -841 |
| Gabarapl2 | 1122.5 | -158 |
| Hbb-bt | -5467.5 | -1469 |
| Hdac6 | 4562.5 | -4546 |
| Hsf1 | -5601.5 | -2640 |
| Hsp90aa1 | -668.5 | -4565 |
| Hsp90ab1 | -5895.5 | 3412 |
| Hspa8 | -6017.5 | -961 |
| Ift88 | 53.5 | 5821 |
| Lamp2 | -2398.5 | 3694 |
| Lamtor1 | -1591.5 | -2294 |
| Lamtor2 | -1725.5 | -3727 |
| Lamtor3 | 1035.5 | 1661 |
| Lamtor4 | -1464.5 | -3509 |
| Lamtor5 | -3075.5 | -3561 |
| Map1lc3a | -3637.5 | 920 |
| Map1lc3b | 1678.5 | 3815 |
| Mfn1 | -2564.5 | 3259 |
| Mfn2 | -2125.5 | 3899 |
| Mlst8 | -3051.5 | 5337 |
| Mterf3 | 3141.5 | 2991 |
| Mtmr14 | 486.5 | 4287 |
| Mtmr3 | -581.5 | 2258 |
| Mtor | -1939.5 | 3306 |
| Mvb12a | -3816.5 | -5003 |
| Mvb12b | -1809.5 | 5191 |
| Nbr1 | -16.5 | 4072 |
| Park7 | -4463.5 | -2564 |
| Pcnt | -640.5 | 4412 |
| Pex5 | -5172.5 | -197 |
| Pgam5 | -4296.5 | 5336 |
| Pik3c3 | 2903.5 | 3734 |
| Pik3r4 | -2454.5 | 1152 |
| Pink1 | -532.5 | 5417 |
| Plin2 | 1794.5 | 2930 |
| Plin3 | -2361.5 | -3422 |
| Prkaa1 | -1389.5 | 668 |
| Prkaa2 | 3048.5 | 4407 |
| Prkab1 | -2504.5 | 2106 |
| Prkab2 | -1248.5 | 3948 |
| Prkag1 | -70.5 | -1019 |
| Prkag2 | 5723.5 | -299 |
| Prkag3 | -2946.5 | -4836 |
| Rb1cc1 | 841.5 | 3944 |
| Rheb | 301.5 | 1364 |
| Rps27a | -4190.5 | -4207 |
| Rptor | -4005.5 | 2914 |
| Rraga | -1102.5 | 2836 |
| Rragc | 1451.5 | 2881 |
| Rragd | 4098.5 | 2118 |
| Slc38a9 | 390.5 | -32 |
| Sqstm1 | -4504.5 | 3770 |
| Src | 5217.5 | -2972 |
| Tomm20 | 506.5 | -993 |
| Tomm22 | 1419.5 | -1109 |
| Tomm40 | -5263.5 | -86 |
| Tomm5 | -3077.5 | -2029 |
| Tomm6 | -4094.5 | -1309 |
| Tomm7 | 2819.5 | -3129 |
| Tomm70a | -3762.5 | 2273 |
| Tsc1 | 998.5 | 766 |
| Tsc2 | -5449.5 | 4564 |
| Tsg101 | 299.5 | 2530 |
| Uba52 | -2952.5 | -3903 |
| Ubap1 | -4066.5 | 2508 |
| Ubb | -2267.5 | -1407 |
| Ube2v1 | -567.5 | -828 |
| Ulk1 | -5479.5 | 2380 |
| Usp30 | -2017.5 | 1992 |
| Uvrag | 3966.5 | 2827 |
| Vcp | -4619.5 | 5396 |
| Vdac1 | -3120.5 | 5253 |
| Vps37a | -2127.5 | -8 |
| Vps37b | 4534.5 | -288 |
| Vps37c | -5354.5 | -2645 |
| Wdr45 | -4890.5 | -3451 |
| Wdr45b | -5256.5 | 1826 |
| Wipi1 | -4477.5 | 2336 |
| Wipi2 | 896.5 | -4124 |
Macroautophagy
| metric | value |
|---|---|
| setSize | 106 |
| pMANOVA | 0.00777 |
| p.adjustMANOVA | 0.00832 |
| s.dist | 0.184 |
| s.ab | -0.109 |
| s.d36 | 0.148 |
| p.ab | 0.052 |
| p.d36 | 0.00882 |
| Gene | ab | d36 |
|---|---|---|
| Atg9a | -5319.5 | 4961 |
| Vcp | -4619.5 | 5396 |
| Tsc2 | -5449.5 | 4564 |
| Pgam5 | -4296.5 | 5336 |
| Dynll2 | -4915.5 | 4603 |
| Sqstm1 | -4504.5 | 3770 |
| Vdac1 | -3120.5 | 5253 |
| Mlst8 | -3051.5 | 5337 |
| Chmp4c | -4050.5 | 3228 |
| Ulk1 | -5479.5 | 2380 |
| Atg4b | -4652.5 | 2598 |
| Rptor | -4005.5 | 2914 |
| Epas1 | -3598.5 | 2954 |
| Wipi1 | -4477.5 | 2336 |
| Atg4d | -2309.5 | 4452 |
| Wdr45b | -5256.5 | 1826 |
| Dync1li2 | -2486.5 | 3478 |
| Tomm70a | -3762.5 | 2273 |
| Mfn1 | -2564.5 | 3259 |
| Mfn2 | -2125.5 | 3899 |
Click HERE to show all gene set members
| ab | d36 | |
|---|---|---|
| Ambra1 | 2209.5 | 865 |
| Arl13b | 3535.5 | 2626 |
| Atg10 | 2771.5 | 245 |
| Atg101 | 5752.5 | -4595 |
| Atg12 | -348.5 | 1754 |
| Atg13 | -3298.5 | 247 |
| Atg14 | -2991.5 | 2109 |
| Atg16l1 | -2053.5 | 1151 |
| Atg3 | -3579.5 | -1582 |
| Atg4a | 4391.5 | 591 |
| Atg4b | -4652.5 | 2598 |
| Atg4c | 5467.5 | 1478 |
| Atg4d | -2309.5 | 4452 |
| Atg5 | 5122.5 | 2910 |
| Atg7 | -2197.5 | 1108 |
| Atg9a | -5319.5 | 4961 |
| Atm | 911.5 | 516 |
| Becn1 | 2652.5 | -673 |
| Chmp2a | 930.5 | -2707 |
| Chmp2b | -3820.5 | 1878 |
| Chmp3 | 4527.5 | 210 |
| Chmp4b | 4442.5 | -2976 |
| Chmp4c | -4050.5 | 3228 |
| Chmp6 | -53.5 | 3017 |
| Chmp7 | 442.5 | -2541 |
| Csnk2a1 | 966.5 | 3203 |
| Csnk2a2 | -1462.5 | -3339 |
| Csnk2b | 268.5 | -2671 |
| Dync1h1 | -5568.5 | 1394 |
| Dync1i2 | 2734.5 | -3975 |
| Dync1li1 | -2517.5 | 1393 |
| Dync1li2 | -2486.5 | 3478 |
| Dynll1 | 372.5 | -5867 |
| Dynll2 | -4915.5 | 4603 |
| Epas1 | -3598.5 | 2954 |
| Fundc1 | 3006.5 | 4373 |
| Gabarap | 3820.5 | 179 |
| Gabarapl1 | 3101.5 | -841 |
| Gabarapl2 | 1122.5 | -158 |
| Hdac6 | 4562.5 | -4546 |
| Hsf1 | -5601.5 | -2640 |
| Hsp90aa1 | -668.5 | -4565 |
| Hspa8 | -6017.5 | -961 |
| Ift88 | 53.5 | 5821 |
| Lamtor1 | -1591.5 | -2294 |
| Lamtor2 | -1725.5 | -3727 |
| Lamtor3 | 1035.5 | 1661 |
| Lamtor4 | -1464.5 | -3509 |
| Lamtor5 | -3075.5 | -3561 |
| Map1lc3a | -3637.5 | 920 |
| Map1lc3b | 1678.5 | 3815 |
| Mfn1 | -2564.5 | 3259 |
| Mfn2 | -2125.5 | 3899 |
| Mlst8 | -3051.5 | 5337 |
| Mterf3 | 3141.5 | 2991 |
| Mtmr14 | 486.5 | 4287 |
| Mtmr3 | -581.5 | 2258 |
| Mtor | -1939.5 | 3306 |
| Nbr1 | -16.5 | 4072 |
| Park7 | -4463.5 | -2564 |
| Pcnt | -640.5 | 4412 |
| Pex5 | -5172.5 | -197 |
| Pgam5 | -4296.5 | 5336 |
| Pik3c3 | 2903.5 | 3734 |
| Pik3r4 | -2454.5 | 1152 |
| Pink1 | -532.5 | 5417 |
| Plin2 | 1794.5 | 2930 |
| Plin3 | -2361.5 | -3422 |
| Prkaa1 | -1389.5 | 668 |
| Prkaa2 | 3048.5 | 4407 |
| Prkab1 | -2504.5 | 2106 |
| Prkab2 | -1248.5 | 3948 |
| Prkag1 | -70.5 | -1019 |
| Prkag2 | 5723.5 | -299 |
| Prkag3 | -2946.5 | -4836 |
| Rb1cc1 | 841.5 | 3944 |
| Rheb | 301.5 | 1364 |
| Rps27a | -4190.5 | -4207 |
| Rptor | -4005.5 | 2914 |
| Rraga | -1102.5 | 2836 |
| Rragc | 1451.5 | 2881 |
| Rragd | 4098.5 | 2118 |
| Slc38a9 | 390.5 | -32 |
| Sqstm1 | -4504.5 | 3770 |
| Src | 5217.5 | -2972 |
| Tomm20 | 506.5 | -993 |
| Tomm22 | 1419.5 | -1109 |
| Tomm40 | -5263.5 | -86 |
| Tomm5 | -3077.5 | -2029 |
| Tomm6 | -4094.5 | -1309 |
| Tomm7 | 2819.5 | -3129 |
| Tomm70a | -3762.5 | 2273 |
| Tsc1 | 998.5 | 766 |
| Tsc2 | -5449.5 | 4564 |
| Uba52 | -2952.5 | -3903 |
| Ubb | -2267.5 | -1407 |
| Ube2v1 | -567.5 | -828 |
| Ulk1 | -5479.5 | 2380 |
| Usp30 | -2017.5 | 1992 |
| Uvrag | 3966.5 | 2827 |
| Vcp | -4619.5 | 5396 |
| Vdac1 | -3120.5 | 5253 |
| Wdr45 | -4890.5 | -3451 |
| Wdr45b | -5256.5 | 1826 |
| Wipi1 | -4477.5 | 2336 |
| Wipi2 | 896.5 | -4124 |
Hemostasis
| metric | value |
|---|---|
| setSize | 373 |
| pMANOVA | 4.84e-08 |
| p.adjustMANOVA | 7.26e-07 |
| s.dist | 0.184 |
| s.ab | 0.0944 |
| s.d36 | -0.157 |
| p.ab | 0.00188 |
| p.d36 | 2.15e-07 |
| Gene | ab | d36 |
|---|---|---|
| Ighm | 5777.5 | -5836 |
| Pecam1 | 5435.5 | -6005 |
| Anxa5 | 5360.5 | -5944 |
| Gng2 | 5782.5 | -5206 |
| F2r | 5371.5 | -5362 |
| Stxbp2 | 5568.5 | -5055 |
| Cav1 | 4754.5 | -5886 |
| Tnfrsf10b | 4726.5 | -5898 |
| Prkch | 4679.5 | -5771 |
| Slc3a2 | 4587.5 | -5542 |
| Atp2b4 | 5523.5 | -4459 |
| Cdc42 | 4469.5 | -5470 |
| Sdc4 | 4437.5 | -5343 |
| Gng10 | 5579.5 | -4220 |
| Angpt2 | 4041.5 | -5764 |
| Tmsb4x | 4551.5 | -4975 |
| Atp1b3 | 5168.5 | -4262 |
| Slc7a6 | 4648.5 | -4568 |
| Nos3 | 3513.5 | -5802 |
| Plaur | 3556.5 | -5596 |
Click HERE to show all gene set members
| ab | d36 | |
|---|---|---|
| Aamp | -2258.5 | -4951 |
| Abcc4 | 1970.5 | -1670 |
| Abhd12 | 3748.5 | 806 |
| Abhd6 | 3805.5 | 2851 |
| Abl1 | -5917.5 | -1584 |
| Actn1 | -4604.5 | -5024 |
| Actn2 | -5378.5 | 2638 |
| Actn4 | 761.5 | -5850 |
| Ahsg | 5563.5 | -1015 |
| Ak3 | 1655.5 | 3841 |
| Akap1 | -5685.5 | 4064 |
| Akap10 | 4192.5 | 926 |
| Akt1 | -4927.5 | -1552 |
| Angpt1 | 5452.5 | 4098 |
| Angpt2 | 4041.5 | -5764 |
| Anxa2 | 1817.5 | -5866 |
| Anxa5 | 5360.5 | -5944 |
| Apbb1ip | -1738.5 | -4000 |
| Aplp2 | 5669.5 | 2725 |
| Apool | -130.5 | 1786 |
| App | 1275.5 | -4045 |
| Arrb1 | 3464.5 | -5200 |
| Arrb2 | 1118.5 | -3266 |
| Atp1b1 | -150.5 | 3208 |
| Atp1b2 | 3667.5 | -5273 |
| Atp1b3 | 5168.5 | -4262 |
| Atp2a2 | -4427.5 | 4366 |
| Atp2a3 | -5259.5 | -1730 |
| Atp2b1 | -5852.5 | 3778 |
| Atp2b4 | 5523.5 | -4459 |
| Bcar1 | 8.5 | -2935 |
| Brpf3 | 1875.5 | 1432 |
| Bsg | -3352.5 | 403 |
| C1qbp | 38.5 | -3395 |
| Cables1 | 2589.5 | -2036 |
| Cables2 | -1651.5 | -3747 |
| Calm1 | 1392.5 | -5536 |
| Calu | 4293.5 | 1275 |
| Cap1 | 3084.5 | -5669 |
| Capza2 | 3526.5 | 4640 |
| Capzb | -3444.5 | 2780 |
| Carmil1 | 3195.5 | 4226 |
| Cav1 | 4754.5 | -5886 |
| Cbx5 | 4923.5 | 1358 |
| Cd36 | -781.5 | 4859 |
| Cd44 | -971.5 | -178 |
| Cd47 | 2621.5 | -3150 |
| Cd63 | 150.5 | -5851 |
| Cd74 | -4666.5 | -1586 |
| Cd9 | 3960.5 | -3699 |
| Cd99l2 | 3656.5 | 2826 |
| Cdc37l1 | 1017.5 | 1851 |
| Cdc42 | 4469.5 | -5470 |
| Cdk2 | 2380.5 | -2178 |
| Cdk5 | 2170.5 | -870 |
| Ceacam1 | -4309.5 | -2032 |
| Cfl1 | 3267.5 | -5778 |
| Chid1 | -1245.5 | 573 |
| Clec3b | 1665.5 | -4649 |
| Clu | 5327.5 | -920 |
| Crk | 7.5 | 1367 |
| Csk | 1857.5 | 2296 |
| Cyb5r1 | 3179.5 | -5170 |
| Dagla | 4069.5 | -2639 |
| Daglb | 4662.5 | -2135 |
| Dgka | 3496.5 | -3918 |
| Dgkd | -5950.5 | -1156 |
| Dgke | 2302.5 | -2159 |
| Dgkh | -3593.5 | -5809 |
| Dgkq | -1263.5 | -4705 |
| Dgkz | 1666.5 | -4277 |
| Dock1 | 4487.5 | -517 |
| Dock10 | 2643.5 | 3879 |
| Dock11 | -2625.5 | -300 |
| Dock2 | 14.5 | -3692 |
| Dock4 | 3029.5 | -1786 |
| Dock5 | 3074.5 | 4515 |
| Dock6 | 2690.5 | -5465 |
| Dock7 | 2145.5 | -916 |
| Dock8 | -816.5 | 622 |
| Dock9 | 1354.5 | -1812 |
| Ecm1 | 2398.5 | -3458 |
| Egf | 5376.5 | 5379 |
| Ehd1 | -4042.5 | -5849 |
| Ehd2 | 1686.5 | -6017 |
| Ehd3 | 3174.5 | -2735 |
| Endod1 | 3373.5 | -5527 |
| Esam | -8.5 | -5480 |
| F11r | 1579.5 | -5619 |
| F13a1 | -1455.5 | -4813 |
| F2r | 5371.5 | -5362 |
| F3 | 5454.5 | 2856 |
| Fam3c | 4.5 | 1264 |
| Fam49b | 2543.5 | -789 |
| Fcer1g | -729.5 | -4428 |
| Fermt3 | -342.5 | -4963 |
| Flna | -2651.5 | -5878 |
| Fn1 | 2667.5 | -1637 |
| Fyn | -5007.5 | -5564 |
| Gas6 | 3951.5 | -4537 |
| Gata2 | 3745.5 | -4097 |
| Gata4 | -5268.5 | 4151 |
| Gata6 | 4434.5 | 5503 |
| Glg1 | -5905.5 | 5213 |
| Gna11 | -3119.5 | -3588 |
| Gna12 | 970.5 | 4107 |
| Gna13 | 47.5 | -635 |
| Gnai1 | 4876.5 | 1477 |
| Gnai2 | -2023.5 | -2736 |
| Gnai3 | 4769.5 | -6 |
| Gnaq | 425.5 | -2832 |
| Gnas | -4213.5 | -844 |
| Gnb1 | 3791.5 | -5197 |
| Gnb2 | -5587.5 | -3631 |
| Gnb3 | -88.5 | -839 |
| Gnb4 | 3274.5 | -5708 |
| Gnb5 | 1823.5 | 3790 |
| Gng10 | 5579.5 | -4220 |
| Gng11 | -2523.5 | -1939 |
| Gng12 | 3603.5 | 954 |
| Gng2 | 5782.5 | -5206 |
| Gng5 | 1661.5 | 505 |
| Gngt2 | 5414.5 | -2034 |
| Gp1ba | -2473.5 | 4196 |
| Gpc1 | -3965.5 | 3658 |
| Grb14 | -4696.5 | 5669 |
| Grb2 | 4354.5 | 5789 |
| Gtpbp2 | -4923.5 | -874 |
| Gypc | 17.5 | 5627 |
| Habp4 | 4847.5 | 2640 |
| Hbb-bt | -5467.5 | -1469 |
| Hdac1 | 5680.5 | -2077 |
| Hdac2 | 4934.5 | 618 |
| Hmg20b | 1476.5 | -3476 |
| Hras | -1991.5 | -5369 |
| Hspa5 | 1696.5 | 1779 |
| Igf1 | 2193.5 | 442 |
| Igf2 | 4185.5 | -3484 |
| Ighm | 5777.5 | -5836 |
| Inpp5d | -4717.5 | -1583 |
| Irf1 | 3743.5 | -4308 |
| Irf2 | -5873.5 | -3194 |
| Islr | 1153.5 | -3144 |
| Itga1 | -4222.5 | -5125 |
| Itga2b | -3203.5 | 5358 |
| Itga3 | 4396.5 | 2383 |
| Itga4 | -1865.5 | -1078 |
| Itga5 | 509.5 | -4981 |
| Itga6 | -4134.5 | -5495 |
| Itgam | 2739.5 | -887 |
| Itgav | 2668.5 | 4851 |
| Itgb1 | 3540.5 | 3163 |
| Itgb3 | 3753.5 | 4308 |
| Itih4 | 945.5 | -4387 |
| Itpk1 | 3823.5 | -2699 |
| Itpr1 | -1288.5 | 1131 |
| Itpr2 | 5652.5 | -2558 |
| Itpr3 | 276.5 | -1493 |
| Jak2 | 3917.5 | 2392 |
| Jam2 | 629.5 | 1356 |
| Jam3 | 4953.5 | -4010 |
| Jmjd1c | 1962.5 | 1712 |
| Kcnmb1 | 3644.5 | -5083 |
| Kdm1a | 326.5 | 1224 |
| Kif13b | 883.5 | -3875 |
| Kif16b | -1703.5 | 4099 |
| Kif1b | 4190.5 | 1990 |
| Kif1c | -5361.5 | 4212 |
| Kif21a | 206.5 | 2371 |
| Kif21b | 4151.5 | -4234 |
| Kif26a | -5359.5 | -4435 |
| Kif26b | -1459.5 | 425 |
| Kif2a | 1261.5 | 710 |
| Kif3a | -3258.5 | 2284 |
| Kif3b | 4282.5 | -3679 |
| Kif3c | 3285.5 | -2306 |
| Kif5a | 5599.5 | 816 |
| Kif5b | -473.5 | -1965 |
| Kif6 | 5739.5 | 3823 |
| Kifap3 | -1786.5 | 2081 |
| Kifc2 | 5221.5 | -764 |
| Klc1 | -4200.5 | -4566 |
| Klc2 | -4010.5 | 1628 |
| Klc4 | 2400.5 | 927 |
| Kras | -403.5 | 1410 |
| L1cam | -2382.5 | -3142 |
| Lamp2 | -2398.5 | 3694 |
| Lgals3bp | 1982.5 | -4128 |
| Lhfpl2 | -514.5 | -5504 |
| Lyn | -5716.5 | -5053 |
| Maff | 3059.5 | -5263 |
| Mafg | -6007.5 | 1644 |
| Mafk | -3649.5 | 1453 |
| Maged2 | 4830.5 | -2690 |
| Manf | 93.5 | -2074 |
| Mapk1 | 2361.5 | 4015 |
| Mapk14 | -2480.5 | 5583 |
| Mapk3 | 435.5 | -5175 |
| Mertk | 1057.5 | -4215 |
| Mfn1 | -2564.5 | 3259 |
| Mfn2 | -2125.5 | 3899 |
| Mgll | -2858.5 | -5344 |
| Mical1 | 166.5 | -5960 |
| Mif | -4023.5 | -4856 |
| Mmrn1 | -4562.5 | 1708 |
| Mrvi1 | 5466.5 | -1625 |
| Nhlrc2 | -2618.5 | 97 |
| Nos2 | -4783.5 | -5692 |
| Nos3 | 3513.5 | -5802 |
| Nras | -2261.5 | -3799 |
| Ola1 | -3044.5 | 2646 |
| Orai1 | -5995.5 | -148 |
| Orai2 | -5357.5 | -2393 |
| P2rx4 | 4218.5 | -734 |
| P2rx5 | 2113.5 | -3334 |
| P2rx6 | -1557.5 | 1072 |
| P2rx7 | 1814.5 | 3680 |
| P2ry1 | -4280.5 | 4663 |
| Pafah2 | -3859.5 | 3642 |
| Pcdh7 | 2816.5 | 4457 |
| Pcyox1l | 384.5 | -5683 |
| Pde10a | 3545.5 | 1678 |
| Pde11a | -5180.5 | 3418 |
| Pde1a | -171.5 | -4009 |
| Pde1b | 3152.5 | -3847 |
| Pde2a | 4039.5 | -2498 |
| Pde5a | -2615.5 | -2410 |
| Pde9a | -2745.5 | -4063 |
| Pdgfa | 3387.5 | -2200 |
| Pdgfb | -3484.5 | -5070 |
| Pdpk1 | -45.5 | 1828 |
| Pdpn | 4867.5 | -233 |
| Pecam1 | 5435.5 | -6005 |
| Pf4 | -3306.5 | 2460 |
| Pfn1 | -5043.5 | -4955 |
| Phactr2 | 4578.5 | 5370 |
| Phf21a | 3811.5 | 1524 |
| Pick1 | -3000.5 | -1008 |
| Pik3ca | -75.5 | 473 |
| Pik3cb | 3253.5 | 4883 |
| Pik3cg | 60.5 | -1882 |
| Pik3r1 | -2910.5 | 4811 |
| Pik3r2 | -347.5 | 2632 |
| Pik3r3 | -407.5 | 5080 |
| Pik3r5 | -4833.5 | -833 |
| Pik3r6 | -4891.5 | -5133 |
| Pla2g4a | 5119.5 | 1798 |
| Plat | 2740.5 | -4008 |
| Plau | -5764.5 | -5517 |
| Plaur | 3556.5 | -5596 |
| Plcg1 | -249.5 | -2602 |
| Plcg2 | -4984.5 | -2505 |
| Plek | -4203.5 | 4068 |
| Ppbp | -5362.5 | 1767 |
| Ppia | 808.5 | -4794 |
| Ppil2 | -2307.5 | 2412 |
| Ppp2ca | 1855.5 | 200 |
| Ppp2cb | 463.5 | -5355 |
| Ppp2r1a | -2019.5 | 2680 |
| Ppp2r1b | 3291.5 | -3140 |
| Ppp2r5a | 4690.5 | 4466 |
| Ppp2r5b | -5396.5 | -2327 |
| Ppp2r5c | -59.5 | 3952 |
| Ppp2r5d | 847.5 | 1273 |
| Ppp2r5e | -2655.5 | 3114 |
| Prcp | -927.5 | -2489 |
| Prkaca | -3696.5 | 4801 |
| Prkacb | 2024.5 | 3919 |
| Prkar1a | -2930.5 | 1502 |
| Prkar1b | 1365.5 | -750 |
| Prkar2a | -421.5 | 2585 |
| Prkca | -5946.5 | 5085 |
| Prkcd | 215.5 | -2497 |
| Prkce | -4307.5 | 577 |
| Prkcg | -808.5 | -2608 |
| Prkch | 4679.5 | -5771 |
| Prkcq | -3480.5 | 5620 |
| Prkcz | 1484.5 | 23 |
| Prkg1 | 3736.5 | 3560 |
| Pros1 | 4179.5 | 4962 |
| Psap | -2543.5 | 4562 |
| Ptgir | -2102.5 | -4300 |
| Ptk2 | -1152.5 | 2180 |
| Ptpn1 | 1809.5 | -279 |
| Ptpn11 | 1827.5 | 1935 |
| Ptpn6 | -4724.5 | -2054 |
| Qsox1 | 5388.5 | -1619 |
| Rab5a | 4811.5 | 4014 |
| Rac1 | 2298.5 | 4382 |
| Rac2 | -5517.5 | -4638 |
| Raf1 | -1990.5 | 4957 |
| Rap1a | 300.5 | -17 |
| Rap1b | 3328.5 | -3725 |
| Rapgef3 | -1405.5 | -5900 |
| Rapgef4 | -5554.5 | -1226 |
| Rarres2 | 5080.5 | -3052 |
| Rasgrp2 | -5264.5 | -4030 |
| Rbsn | 471.5 | 1298 |
| Rcor1 | 170.5 | 2353 |
| Rhob | -4872.5 | 919 |
| Rhog | -4736.5 | -5706 |
| S100a10 | 2908.5 | -4729 |
| Sccpdh | 227.5 | 922 |
| Sdc1 | 405.5 | -4246 |
| Sdc2 | 115.5 | -1758 |
| Sdc3 | -5229.5 | -5685 |
| Sdc4 | 4437.5 | -5343 |
| Selenop | 3557.5 | 571 |
| Selplg | -1041.5 | -2465 |
| Serpinc1 | 533.5 | 2882 |
| Serpine1 | 743.5 | 1911 |
| Serpine2 | 1273.5 | 2078 |
| Serping1 | 1907.5 | 957 |
| Sh2b1 | -923.5 | 1127 |
| Sh2b3 | -3282.5 | -5615 |
| Shc1 | 3979.5 | -3058 |
| Sin3a | 2117.5 | 948 |
| Sirpa | -1642.5 | 1097 |
| Slc16a1 | -3831.5 | 892 |
| Slc16a3 | 3452.5 | -5626 |
| Slc3a2 | 4587.5 | -5542 |
| Slc7a5 | 4006.5 | -3723 |
| Slc7a6 | 4648.5 | -4568 |
| Slc7a7 | 5746.5 | -1805 |
| Slc7a8 | 5528.5 | 1390 |
| Slc8a1 | 657.5 | 1397 |
| Sod1 | -2867.5 | -2270 |
| Sos1 | 5252.5 | 584 |
| Sparc | 1782.5 | -5058 |
| Src | 5217.5 | -2972 |
| Srgn | -2390.5 | -4889 |
| Sri | 158.5 | -1854 |
| Stim1 | 4737.5 | -500 |
| Stx4a | 1559.5 | -4819 |
| Stxbp2 | 5568.5 | -5055 |
| Stxbp3 | 2651.5 | 5234 |
| Syk | 2745.5 | -5361 |
| Tagln2 | 3069.5 | -6000 |
| Tek | -5283.5 | -5759 |
| Tex264 | 2147.5 | -4792 |
| Tfpi | 5757.5 | 1864 |
| Tgfb1 | 2887.5 | -5464 |
| Tgfb2 | 1211.5 | 4752 |
| Tgfb3 | 3734.5 | 1657 |
| Thbd | -5945.5 | -4554 |
| Thbs1 | -3465.5 | 845 |
| Timp3 | 3838.5 | -3256 |
| Tln1 | -1108.5 | -4050 |
| Tmsb4x | 4551.5 | -4975 |
| Tmx3 | 3789.5 | -879 |
| Tnfrsf10b | 4726.5 | -5898 |
| Tor4a | -2973.5 | -4855 |
| Trp53 | 2017.5 | -5882 |
| Trpc3 | 517.5 | -2446 |
| Tspan7 | 494.5 | -3822 |
| Ttn | -2540.5 | -1189 |
| Tuba4a | -4968.5 | -2273 |
| Vav1 | -3902.5 | -2109 |
| Vav2 | -4195.5 | 5285 |
| Vav3 | -4031.5 | -177 |
| Vcl | 1603.5 | 3237 |
| Vegfa | -4638.5 | -5624 |
| Vegfb | -3753.5 | 1571 |
| Vegfc | -1320.5 | -4431 |
| Vegfd | 2021.5 | 1617 |
| Vps45 | 3898.5 | -4477 |
| Vti1b | -2278.5 | 280 |
| Vwf | 3593.5 | -1888 |
| Wdr1 | -5756.5 | -568 |
| Wee1 | -4384.5 | 5841 |
| Yes1 | -232.5 | 2379 |
| Zfpm1 | -2931.5 | -1290 |
| Zfpm2 | 3920.5 | 5482 |
Chromatin-modifying-enzymes
| metric | value |
|---|---|
| setSize | 188 |
| pMANOVA | 0.000634 |
| p.adjustMANOVA | 0.00106 |
| s.dist | 0.171 |
| s.ab | -0.111 |
| s.d36 | 0.13 |
| p.ab | 0.0091 |
| p.d36 | 0.00221 |
| Gene | ab | d36 |
|---|---|---|
| Ncor2 | -6013.5 | 5325 |
| Kdm4a | -5379.5 | 4692 |
| Prmt5 | -4452.5 | 5391 |
| Mta1 | -5300.5 | 4441 |
| Arid1b | -5963.5 | 3855 |
| Kdm4b | -4883.5 | 4524 |
| Kmt5a | -5669.5 | 3828 |
| Setd7 | -4414.5 | 4584 |
| Smyd3 | -3769.5 | 5212 |
| Ash2l | -4754.5 | 3907 |
| Ing4 | -5810.5 | 3156 |
| Hcfc1 | -5321.5 | 3434 |
| Smarca4 | -4251.5 | 4134 |
| Ep300 | -5499.5 | 3153 |
| Aebp2 | -4408.5 | 3840 |
| Smarcc2 | -3873.5 | 4359 |
| Msl2 | -3244.5 | 5048 |
| Smarcd1 | -3463.5 | 4630 |
| Taf5l | -4283.5 | 3689 |
| Gatad2b | -2964.5 | 5170 |
Click HERE to show all gene set members
| ab | d36 | |
|---|---|---|
| Actb | -3121.5 | -5814 |
| Actl6a | -4.5 | -2537 |
| Aebp2 | -4408.5 | 3840 |
| Ak6 | -2848.5 | -3257 |
| Arid1a | -5941.5 | 517 |
| Arid1b | -5963.5 | 3855 |
| Arid2 | -3072.5 | -337 |
| Arid4a | 4173.5 | -4622 |
| Arid4b | 4372.5 | 628 |
| Arid5b | 106.5 | 4016 |
| Ash1l | 1544.5 | 3997 |
| Ash2l | -4754.5 | 3907 |
| Atf2 | 4155.5 | 2027 |
| Atf7ip | -1085.5 | 3288 |
| Atxn7 | -2864.5 | -4913 |
| Atxn7l3 | -207.5 | 2359 |
| Brd1 | -1507.5 | 903 |
| Brd8 | 5196.5 | 4112 |
| Brms1 | 4409.5 | 1689 |
| Brpf1 | -1510.5 | -83 |
| Brpf3 | 1875.5 | 1432 |
| Brwd1 | -2526.5 | 1177 |
| Carm1 | -1486.5 | 415 |
| Ccnd1 | -5221.5 | -4437 |
| Cdk4 | 5651.5 | -1856 |
| Chd3 | 3853.5 | 1872 |
| Chd4 | -3144.5 | 4581 |
| Clock | -2313.5 | 3232 |
| Coprs | 4322.5 | -3106 |
| Crebbp | -4690.5 | -2773 |
| Dmap1 | -3700.5 | -5796 |
| Dnmt3a | -5862.5 | -473 |
| Dot1l | -5484.5 | -1256 |
| Dpy30 | -341.5 | -2478 |
| Dr1 | 1530.5 | 5522 |
| Eed | -4857.5 | 612 |
| Ehmt1 | -5831.5 | 1713 |
| Ehmt2 | -2988.5 | -2295 |
| Elp2 | 5424.5 | -3734 |
| Elp3 | 916.5 | 4702 |
| Elp4 | -551.5 | 2666 |
| Elp5 | 1384.5 | 781 |
| Eny2 | 3773.5 | -4716 |
| Ep300 | -5499.5 | 3153 |
| Ep400 | -3982.5 | 1746 |
| Epc1 | -5428.5 | 2775 |
| Ezh2 | 4416.5 | 1277 |
| Gatad2a | -5068.5 | -5102 |
| Gatad2b | -2964.5 | 5170 |
| Gps2 | -1334.5 | -2824 |
| Hat1 | 622.5 | 5340 |
| Hcfc1 | -5321.5 | 3434 |
| Hdac1 | 5680.5 | -2077 |
| Hdac10 | -4060.5 | -1895 |
| Hdac2 | 4934.5 | 618 |
| Hdac3 | 1519.5 | 3701 |
| Hdac8 | -2327.5 | -5375 |
| Hmg20b | 1476.5 | -3476 |
| Ing3 | 3472.5 | -2958 |
| Ing4 | -5810.5 | 3156 |
| Ing5 | 541.5 | 3415 |
| Jade1 | 2490.5 | 3161 |
| Jade2 | 3851.5 | 3660 |
| Jade3 | -1402.5 | 801 |
| Jak2 | 3917.5 | 2392 |
| Jmjd6 | -5213.5 | -4256 |
| Kansl1 | -3007.5 | 1014 |
| Kansl2 | -5836.5 | 1297 |
| Kansl3 | -1196.5 | 1882 |
| Kat2a | -3851.5 | -3000 |
| Kat2b | -304.5 | 4890 |
| Kat5 | -388.5 | 302 |
| Kat6a | -377.5 | 3545 |
| Kat6b | 4707.5 | 70 |
| Kat7 | 1916.5 | 5491 |
| Kat8 | -3901.5 | -3211 |
| Kdm1a | 326.5 | 1224 |
| Kdm1b | -2635.5 | 5137 |
| Kdm2a | -4601.5 | 1285 |
| Kdm2b | -5340.5 | 1163 |
| Kdm3a | 2267.5 | 223 |
| Kdm3b | 4313.5 | 722 |
| Kdm4a | -5379.5 | 4692 |
| Kdm4b | -4883.5 | 4524 |
| Kdm4c | 863.5 | 3845 |
| Kdm5a | -802.5 | -1650 |
| Kdm5b | 167.5 | 3750 |
| Kdm5c | -6012.5 | 1482 |
| Kdm5d | 4547.5 | 4604 |
| Kdm6a | -228.5 | 872 |
| Kdm6b | -4124.5 | 3341 |
| Kdm7a | 252.5 | -369 |
| Kmt2a | -2788.5 | -3044 |
| Kmt2b | -5854.5 | -2384 |
| Kmt2c | -4494.5 | 1734 |
| Kmt2d | -5416.5 | -3411 |
| Kmt2e | -2370.5 | 1596 |
| Kmt5a | -5669.5 | 3828 |
| Kmt5b | 2967.5 | -434 |
| Kmt5c | 1760.5 | -122 |
| Mbd3 | -5819.5 | -640 |
| Mbip | -461.5 | -1139 |
| Mcrs1 | 1927.5 | 1252 |
| Meaf6 | -1973.5 | 1261 |
| Mecom | 5231.5 | -2248 |
| Morf4l1 | 5366.5 | 5151 |
| Morf4l2 | 5058.5 | -1631 |
| Mrgbp | 4896.5 | -2598 |
| Msl1 | -5459.5 | 438 |
| Msl2 | -3244.5 | 5048 |
| Mta1 | -5300.5 | 4441 |
| Mta2 | 1465.5 | -3148 |
| Mta3 | -817.5 | 165 |
| Ncoa1 | 1438.5 | 1348 |
| Ncoa2 | -2612.5 | 3525 |
| Ncor1 | -3731.5 | 3973 |
| Ncor2 | -6013.5 | 5325 |
| Nfkb1 | -1460.5 | -939 |
| Nfkb2 | 830.5 | 4906 |
| Nsd1 | -134.5 | 1949 |
| Ogt | -3825.5 | 2781 |
| Pbrm1 | 2436.5 | 684 |
| Phf2 | -4116.5 | 2655 |
| Phf20 | 3517.5 | 1825 |
| Phf21a | 3811.5 | 1524 |
| Phf8 | -1799.5 | 4464 |
| Prdm16 | -3809.5 | 1788 |
| Prdm9 | -2147.5 | -4864 |
| Prmt1 | -3493.5 | -4858 |
| Prmt3 | 3163.5 | 5618 |
| Prmt5 | -4452.5 | 5391 |
| Prmt6 | 680.5 | -5069 |
| Prmt7 | -4841.5 | -5278 |
| Rbbp4 | 5510.5 | -634 |
| Rbbp5 | -1857.5 | 4372 |
| Rbbp7 | 2413.5 | 3592 |
| Rcor1 | 170.5 | 2353 |
| Rela | 1205.5 | -4015 |
| Rest | -1227.5 | 2803 |
| Ruvbl1 | -1995.5 | -2138 |
| Ruvbl2 | -4262.5 | -2720 |
| Sap130 | 1526.5 | 3409 |
| Sap18 | 753.5 | -491 |
| Sap30 | -2095.5 | -3590 |
| Sap30l | 2087.5 | -1699 |
| Setd1b | -3738.5 | 2357 |
| Setd2 | 147.5 | 1647 |
| Setd3 | 831.5 | 3234 |
| Setd6 | 2763.5 | -3998 |
| Setd7 | -4414.5 | 4584 |
| Setdb1 | -3409.5 | -1410 |
| Setdb2 | 5448.5 | 5827 |
| Sgf29 | 766.5 | -4614 |
| Smarca2 | 2614.5 | 4273 |
| Smarca4 | -4251.5 | 4134 |
| Smarcb1 | 56.5 | -5576 |
| Smarcc1 | -472.5 | 2899 |
| Smarcc2 | -3873.5 | 4359 |
| Smarcd1 | -3463.5 | 4630 |
| Smarcd2 | 1523.5 | -5571 |
| Smarcd3 | 5640.5 | -3365 |
| Smarce1 | -639.5 | -1355 |
| Smyd2 | -3636.5 | -1239 |
| Smyd3 | -3769.5 | 5212 |
| Suds3 | -818.5 | 3741 |
| Supt20 | 4603.5 | -1599 |
| Supt3 | -944.5 | -2311 |
| Supt7l | 161.5 | 3906 |
| Suv39h1 | 4674.5 | -1900 |
| Suz12 | 3346.5 | 4522 |
| Tada1 | -736.5 | -37 |
| Tada2a | 4710.5 | 1811 |
| Tada2b | -502.5 | 3727 |
| Tada3 | -925.5 | 2501 |
| Taf10 | -557.5 | -4980 |
| Taf12 | 1306.5 | 226 |
| Taf5l | -4283.5 | 3689 |
| Taf6l | -1655.5 | -4285 |
| Tbl1xr1 | -2360.5 | 498 |
| Trrap | -2256.5 | -2215 |
| Usp22 | -4083.5 | 319 |
| Uty | 1154.5 | 1681 |
| Vps72 | -1337.5 | -1067 |
| Wdr5 | -2834.5 | 754 |
| Wdr77 | -5205.5 | -1573 |
| Yeats2 | 3573.5 | -563 |
| Yeats4 | -5403.5 | -1163 |
| Zzz3 | 3190.5 | 682 |
Chromatin-organization
| metric | value |
|---|---|
| setSize | 188 |
| pMANOVA | 0.000634 |
| p.adjustMANOVA | 0.00106 |
| s.dist | 0.171 |
| s.ab | -0.111 |
| s.d36 | 0.13 |
| p.ab | 0.0091 |
| p.d36 | 0.00221 |
| Gene | ab | d36 |
|---|---|---|
| Ncor2 | -6013.5 | 5325 |
| Kdm4a | -5379.5 | 4692 |
| Prmt5 | -4452.5 | 5391 |
| Mta1 | -5300.5 | 4441 |
| Arid1b | -5963.5 | 3855 |
| Kdm4b | -4883.5 | 4524 |
| Kmt5a | -5669.5 | 3828 |
| Setd7 | -4414.5 | 4584 |
| Smyd3 | -3769.5 | 5212 |
| Ash2l | -4754.5 | 3907 |
| Ing4 | -5810.5 | 3156 |
| Hcfc1 | -5321.5 | 3434 |
| Smarca4 | -4251.5 | 4134 |
| Ep300 | -5499.5 | 3153 |
| Aebp2 | -4408.5 | 3840 |
| Smarcc2 | -3873.5 | 4359 |
| Msl2 | -3244.5 | 5048 |
| Smarcd1 | -3463.5 | 4630 |
| Taf5l | -4283.5 | 3689 |
| Gatad2b | -2964.5 | 5170 |
Click HERE to show all gene set members
| ab | d36 | |
|---|---|---|
| Actb | -3121.5 | -5814 |
| Actl6a | -4.5 | -2537 |
| Aebp2 | -4408.5 | 3840 |
| Ak6 | -2848.5 | -3257 |
| Arid1a | -5941.5 | 517 |
| Arid1b | -5963.5 | 3855 |
| Arid2 | -3072.5 | -337 |
| Arid4a | 4173.5 | -4622 |
| Arid4b | 4372.5 | 628 |
| Arid5b | 106.5 | 4016 |
| Ash1l | 1544.5 | 3997 |
| Ash2l | -4754.5 | 3907 |
| Atf2 | 4155.5 | 2027 |
| Atf7ip | -1085.5 | 3288 |
| Atxn7 | -2864.5 | -4913 |
| Atxn7l3 | -207.5 | 2359 |
| Brd1 | -1507.5 | 903 |
| Brd8 | 5196.5 | 4112 |
| Brms1 | 4409.5 | 1689 |
| Brpf1 | -1510.5 | -83 |
| Brpf3 | 1875.5 | 1432 |
| Brwd1 | -2526.5 | 1177 |
| Carm1 | -1486.5 | 415 |
| Ccnd1 | -5221.5 | -4437 |
| Cdk4 | 5651.5 | -1856 |
| Chd3 | 3853.5 | 1872 |
| Chd4 | -3144.5 | 4581 |
| Clock | -2313.5 | 3232 |
| Coprs | 4322.5 | -3106 |
| Crebbp | -4690.5 | -2773 |
| Dmap1 | -3700.5 | -5796 |
| Dnmt3a | -5862.5 | -473 |
| Dot1l | -5484.5 | -1256 |
| Dpy30 | -341.5 | -2478 |
| Dr1 | 1530.5 | 5522 |
| Eed | -4857.5 | 612 |
| Ehmt1 | -5831.5 | 1713 |
| Ehmt2 | -2988.5 | -2295 |
| Elp2 | 5424.5 | -3734 |
| Elp3 | 916.5 | 4702 |
| Elp4 | -551.5 | 2666 |
| Elp5 | 1384.5 | 781 |
| Eny2 | 3773.5 | -4716 |
| Ep300 | -5499.5 | 3153 |
| Ep400 | -3982.5 | 1746 |
| Epc1 | -5428.5 | 2775 |
| Ezh2 | 4416.5 | 1277 |
| Gatad2a | -5068.5 | -5102 |
| Gatad2b | -2964.5 | 5170 |
| Gps2 | -1334.5 | -2824 |
| Hat1 | 622.5 | 5340 |
| Hcfc1 | -5321.5 | 3434 |
| Hdac1 | 5680.5 | -2077 |
| Hdac10 | -4060.5 | -1895 |
| Hdac2 | 4934.5 | 618 |
| Hdac3 | 1519.5 | 3701 |
| Hdac8 | -2327.5 | -5375 |
| Hmg20b | 1476.5 | -3476 |
| Ing3 | 3472.5 | -2958 |
| Ing4 | -5810.5 | 3156 |
| Ing5 | 541.5 | 3415 |
| Jade1 | 2490.5 | 3161 |
| Jade2 | 3851.5 | 3660 |
| Jade3 | -1402.5 | 801 |
| Jak2 | 3917.5 | 2392 |
| Jmjd6 | -5213.5 | -4256 |
| Kansl1 | -3007.5 | 1014 |
| Kansl2 | -5836.5 | 1297 |
| Kansl3 | -1196.5 | 1882 |
| Kat2a | -3851.5 | -3000 |
| Kat2b | -304.5 | 4890 |
| Kat5 | -388.5 | 302 |
| Kat6a | -377.5 | 3545 |
| Kat6b | 4707.5 | 70 |
| Kat7 | 1916.5 | 5491 |
| Kat8 | -3901.5 | -3211 |
| Kdm1a | 326.5 | 1224 |
| Kdm1b | -2635.5 | 5137 |
| Kdm2a | -4601.5 | 1285 |
| Kdm2b | -5340.5 | 1163 |
| Kdm3a | 2267.5 | 223 |
| Kdm3b | 4313.5 | 722 |
| Kdm4a | -5379.5 | 4692 |
| Kdm4b | -4883.5 | 4524 |
| Kdm4c | 863.5 | 3845 |
| Kdm5a | -802.5 | -1650 |
| Kdm5b | 167.5 | 3750 |
| Kdm5c | -6012.5 | 1482 |
| Kdm5d | 4547.5 | 4604 |
| Kdm6a | -228.5 | 872 |
| Kdm6b | -4124.5 | 3341 |
| Kdm7a | 252.5 | -369 |
| Kmt2a | -2788.5 | -3044 |
| Kmt2b | -5854.5 | -2384 |
| Kmt2c | -4494.5 | 1734 |
| Kmt2d | -5416.5 | -3411 |
| Kmt2e | -2370.5 | 1596 |
| Kmt5a | -5669.5 | 3828 |
| Kmt5b | 2967.5 | -434 |
| Kmt5c | 1760.5 | -122 |
| Mbd3 | -5819.5 | -640 |
| Mbip | -461.5 | -1139 |
| Mcrs1 | 1927.5 | 1252 |
| Meaf6 | -1973.5 | 1261 |
| Mecom | 5231.5 | -2248 |
| Morf4l1 | 5366.5 | 5151 |
| Morf4l2 | 5058.5 | -1631 |
| Mrgbp | 4896.5 | -2598 |
| Msl1 | -5459.5 | 438 |
| Msl2 | -3244.5 | 5048 |
| Mta1 | -5300.5 | 4441 |
| Mta2 | 1465.5 | -3148 |
| Mta3 | -817.5 | 165 |
| Ncoa1 | 1438.5 | 1348 |
| Ncoa2 | -2612.5 | 3525 |
| Ncor1 | -3731.5 | 3973 |
| Ncor2 | -6013.5 | 5325 |
| Nfkb1 | -1460.5 | -939 |
| Nfkb2 | 830.5 | 4906 |
| Nsd1 | -134.5 | 1949 |
| Ogt | -3825.5 | 2781 |
| Pbrm1 | 2436.5 | 684 |
| Phf2 | -4116.5 | 2655 |
| Phf20 | 3517.5 | 1825 |
| Phf21a | 3811.5 | 1524 |
| Phf8 | -1799.5 | 4464 |
| Prdm16 | -3809.5 | 1788 |
| Prdm9 | -2147.5 | -4864 |
| Prmt1 | -3493.5 | -4858 |
| Prmt3 | 3163.5 | 5618 |
| Prmt5 | -4452.5 | 5391 |
| Prmt6 | 680.5 | -5069 |
| Prmt7 | -4841.5 | -5278 |
| Rbbp4 | 5510.5 | -634 |
| Rbbp5 | -1857.5 | 4372 |
| Rbbp7 | 2413.5 | 3592 |
| Rcor1 | 170.5 | 2353 |
| Rela | 1205.5 | -4015 |
| Rest | -1227.5 | 2803 |
| Ruvbl1 | -1995.5 | -2138 |
| Ruvbl2 | -4262.5 | -2720 |
| Sap130 | 1526.5 | 3409 |
| Sap18 | 753.5 | -491 |
| Sap30 | -2095.5 | -3590 |
| Sap30l | 2087.5 | -1699 |
| Setd1b | -3738.5 | 2357 |
| Setd2 | 147.5 | 1647 |
| Setd3 | 831.5 | 3234 |
| Setd6 | 2763.5 | -3998 |
| Setd7 | -4414.5 | 4584 |
| Setdb1 | -3409.5 | -1410 |
| Setdb2 | 5448.5 | 5827 |
| Sgf29 | 766.5 | -4614 |
| Smarca2 | 2614.5 | 4273 |
| Smarca4 | -4251.5 | 4134 |
| Smarcb1 | 56.5 | -5576 |
| Smarcc1 | -472.5 | 2899 |
| Smarcc2 | -3873.5 | 4359 |
| Smarcd1 | -3463.5 | 4630 |
| Smarcd2 | 1523.5 | -5571 |
| Smarcd3 | 5640.5 | -3365 |
| Smarce1 | -639.5 | -1355 |
| Smyd2 | -3636.5 | -1239 |
| Smyd3 | -3769.5 | 5212 |
| Suds3 | -818.5 | 3741 |
| Supt20 | 4603.5 | -1599 |
| Supt3 | -944.5 | -2311 |
| Supt7l | 161.5 | 3906 |
| Suv39h1 | 4674.5 | -1900 |
| Suz12 | 3346.5 | 4522 |
| Tada1 | -736.5 | -37 |
| Tada2a | 4710.5 | 1811 |
| Tada2b | -502.5 | 3727 |
| Tada3 | -925.5 | 2501 |
| Taf10 | -557.5 | -4980 |
| Taf12 | 1306.5 | 226 |
| Taf5l | -4283.5 | 3689 |
| Taf6l | -1655.5 | -4285 |
| Tbl1xr1 | -2360.5 | 498 |
| Trrap | -2256.5 | -2215 |
| Usp22 | -4083.5 | 319 |
| Uty | 1154.5 | 1681 |
| Vps72 | -1337.5 | -1067 |
| Wdr5 | -2834.5 | 754 |
| Wdr77 | -5205.5 | -1573 |
| Yeats2 | 3573.5 | -563 |
| Yeats4 | -5403.5 | -1163 |
| Zzz3 | 3190.5 | 682 |
Here is the session info with all the versions of packages used.
sessionInfo()## R version 4.0.0 (2020-04-24)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 18.04.4 LTS
##
## Matrix products: default
## BLAS: /mnt/md0/app/R-4.0.0/lib/libRblas.so
## LAPACK: /mnt/md0/app/R-4.0.0/lib/libRlapack.so
##
## locale:
## [1] LC_CTYPE=en_US.UTF-8 LC_NUMERIC=C
## [3] LC_TIME=en_US.UTF-8 LC_COLLATE=en_US.UTF-8
## [5] LC_MONETARY=en_US.UTF-8 LC_MESSAGES=en_US.UTF-8
## [7] LC_PAPER=en_US.UTF-8 LC_NAME=C
## [9] LC_ADDRESS=C LC_TELEPHONE=C
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C
##
## attached base packages:
## [1] parallel stats4 stats graphics grDevices utils datasets
## [8] methods base
##
## other attached packages:
## [1] pkgload_1.1.0 GGally_1.5.0
## [3] ggplot2_3.3.1 reshape2_1.4.4
## [5] beeswarm_0.2.3 gplots_3.0.3
## [7] gtools_3.8.2 tibble_3.0.1
## [9] dplyr_1.0.0 echarts4r_0.2.3
## [11] mitch_1.0.4 DESeq2_1.28.1
## [13] SummarizedExperiment_1.18.1 DelayedArray_0.14.0
## [15] matrixStats_0.56.0 Biobase_2.48.0
## [17] GenomicRanges_1.40.0 GenomeInfoDb_1.24.0
## [19] IRanges_2.22.2 S4Vectors_0.26.1
## [21] BiocGenerics_0.34.0
##
## loaded via a namespace (and not attached):
## [1] bitops_1.0-6 bit64_0.9-7 RColorBrewer_1.1-2
## [4] rprojroot_1.3-2 tools_4.0.0 backports_1.1.7
## [7] R6_2.4.1 KernSmooth_2.23-17 DBI_1.1.0
## [10] colorspace_1.4-1 withr_2.2.0 tidyselect_1.1.0
## [13] gridExtra_2.3 bit_1.1-15.2 compiler_4.0.0
## [16] desc_1.2.0 labeling_0.3 caTools_1.18.0
## [19] scales_1.1.1 genefilter_1.70.0 stringr_1.4.0
## [22] digest_0.6.25 rmarkdown_2.2 XVector_0.28.0
## [25] pkgconfig_2.0.3 htmltools_0.4.0 fastmap_1.0.1
## [28] highr_0.8 htmlwidgets_1.5.1 rlang_0.4.6
## [31] RSQLite_2.2.0 shiny_1.4.0.2 farver_2.0.3
## [34] generics_0.0.2 jsonlite_1.6.1 BiocParallel_1.22.0
## [37] RCurl_1.98-1.2 magrittr_1.5 GenomeInfoDbData_1.2.3
## [40] Matrix_1.2-18 Rcpp_1.0.4.6 munsell_0.5.0
## [43] lifecycle_0.2.0 stringi_1.4.6 yaml_2.2.1
## [46] MASS_7.3-51.6 zlibbioc_1.34.0 plyr_1.8.6
## [49] grid_4.0.0 blob_1.2.1 gdata_2.18.0
## [52] promises_1.1.0 crayon_1.3.4 lattice_0.20-41
## [55] splines_4.0.0 annotate_1.66.0 locfit_1.5-9.4
## [58] knitr_1.28 pillar_1.4.4 geneplotter_1.66.0
## [61] XML_3.99-0.3 glue_1.4.1 evaluate_0.14
## [64] vctrs_0.3.0 httpuv_1.5.3.1 testthat_2.3.2
## [67] gtable_0.3.0 purrr_0.3.4 reshape_0.8.8
## [70] assertthat_0.2.1 xfun_0.14 mime_0.9
## [73] xtable_1.8-4 later_1.0.0 survival_3.1-12
## [76] pbmcapply_1.5.0 AnnotationDbi_1.50.0 memoise_1.1.0
## [79] ellipsis_0.3.1END of report