Mitch Report

date generated: 2022-09-07

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

## <table>
## <caption>Profile dimensions</caption>
##  <thead>
##   <tr>
##    <th style="text-align:right;"> dimension </th>
##    <th style="text-align:left;"> contrast_name </th>
##   </tr>
##  </thead>
## <tbody>
##   <tr>
##    <td style="text-align:right;"> 1 </td>
##    <td style="text-align:left;"> de1 </td>
##   </tr>
##   <tr>
##    <td style="text-align:right;"> 2 </td>
##    <td style="text-align:left;"> de2 </td>
##   </tr>
##   <tr>
##    <td style="text-align:right;"> 3 </td>
##    <td style="text-align:left;"> de3 </td>
##   </tr>
##   <tr>
##    <td style="text-align:right;"> 4 </td>
##    <td style="text-align:left;"> de4 </td>
##   </tr>
##   <tr>
##    <td style="text-align:right;"> 5 </td>
##    <td style="text-align:left;"> de5 </td>
##   </tr>
##   <tr>
##    <td style="text-align:right;"> 6 </td>
##    <td style="text-align:left;"> de6 </td>
##   </tr>
##   <tr>
##    <td style="text-align:right;"> 7 </td>
##    <td style="text-align:left;"> de7 </td>
##   </tr>
##   <tr>
##    <td style="text-align:right;"> 8 </td>
##    <td style="text-align:left;"> de8 </td>
##   </tr>
## </tbody>
## </table>

##                       d1         d2          d3         d4          d5
## 0610009B22Rik  1.6344600  1.1168615 -0.68382677 -0.5935749 -0.08990061
## 0610009L18Rik  1.0145872  0.2160756  0.56527326  0.2161104 -0.33354482
## 0610010K14Rik  0.1633529  0.6692320  0.66424429 -0.1134635 -1.90686802
## 0610012G03Rik  0.5937955  0.4088542 -0.18505314 -0.3269221  0.01318114
## 0610030E20Rik -0.7027218  0.2111877 -0.38884282 -0.0645616 -0.84194359
## 0610040J01Rik -0.0895336 -1.4975473  0.04555983 -1.2938364  0.62289268
##                       d6         d7         d8
## 0610009B22Rik  0.3047981 -0.5488684 -0.3845554
## 0610009L18Rik -0.2679990  0.7010761  0.7909020
## 0610010K14Rik -0.7218075 -0.2062781  0.5031172
## 0610012G03Rik -0.1786497 -1.0685616 -0.5693632
## 0610030E20Rik -0.4541127  1.0067021  1.1957467
## 0610040J01Rik -1.3376144 -0.6151338 -1.1105356

Here are some metrics about the input data profile:

Profile metrics

	Profile metrics
num_genes_in_profile	9724
duplicated_genes_present	0
num_profile_genes_in_sets	2889
num_profile_genes_not_in_sets	6835

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used: GMT file of genesets: https://ziemann-lab.net/public/msigdb_mouse/reactome.v5.2.symbols_mouse.gmt

Gene sets metrics

	Gene sets metrics
num_genesets	674
num_genesets_excluded	203
num_genesets_included	471

Interactive enrichment scatterplot

All sets with FDR<0.05. Try hovering over the points.

Top N sets irrespective of FDR. Try hovering over the points.

A heatmap of S values for top results

A plot of effect size versus significance

Significance is the -log2(p.adjustMANOVA) and effect size is the s.dist which is the hypotenuse of the s scores.

Results table

Top N= 50 gene sets

set	setSize	pMANOVA	p.adjustMANOVA	s.dist	s.de1	s.de2	s.de3	s.de4	s.de5	s.de6	s.de7	s.de8	p.de1	p.de2	p.de3	p.de4	p.de5	p.de6	p.de7	p.de8
REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	12	4.51e-16	1.25e-14	1.700	0.82300	-0.0381	0.53000	-0.91300	0.80600	0.1210	-0.6640	-0.066100	1.24e-06	8.01e-01	9.50e-04	9.82e-09	1.29e-06	4.73e-01	3.90e-05	6.52e-01
REACTOME CITRIC ACID CYCLE TCA CYCLE	19	8.66e-25	3.40e-23	1.610	0.56900	-0.3640	0.37500	-0.86000	0.78900	0.2090	-0.7620	0.146000	3.30e-05	3.72e-03	3.45e-03	1.14e-11	2.59e-09	1.08e-01	2.97e-09	2.60e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	13	1.04e-13	2.44e-12	1.560	0.53200	-0.6190	0.28100	-0.71000	0.81300	0.1830	-0.6540	0.246000	1.37e-03	4.56e-05	7.12e-02	3.60e-06	3.82e-07	2.48e-01	2.51e-05	1.11e-01
REACTOME RESPIRATORY ELECTRON TRANSPORT	59	2.97e-61	4.66e-59	1.440	0.64300	-0.0432	0.11500	-0.84300	0.69200	0.0772	-0.6710	0.038600	9.05e-17	5.29e-01	1.28e-01	7.79e-32	5.23e-20	3.27e-01	3.38e-20	6.35e-01
REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	73	3.66e-75	8.63e-73	1.420	0.64900	-0.0356	0.18200	-0.82200	0.69700	0.1030	-0.6280	0.023000	1.00e-20	5.61e-01	6.26e-03	3.96e-37	1.02e-24	1.35e-01	9.47e-22	7.77e-01
REACTOME TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT	107	1.00e-100	2.84e-98	1.360	0.59900	-0.1210	0.19500	-0.78800	0.68100	0.1500	-0.5710	0.057700	2.70e-25	2.14e-02	3.78e-04	2.15e-49	6.99e-34	7.17e-03	5.79e-26	3.19e-01
REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	11	8.02e-08	1.11e-06	1.330	0.59000	-0.3210	0.12400	-0.63900	0.69300	0.2900	-0.5220	0.238000	1.02e-03	5.15e-02	4.75e-01	1.28e-04	7.28e-05	8.75e-02	1.97e-03	1.56e-01
REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	38	7.68e-30	3.62e-28	1.290	0.50900	-0.2970	0.24000	-0.72400	0.66000	0.2210	-0.4820	0.120000	1.75e-07	7.93e-04	8.72e-03	6.61e-16	2.43e-12	1.66e-02	1.12e-07	1.92e-01
REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	11	7.59e-06	6.27e-05	1.210	0.15400	0.5090	0.58500	0.44500	0.06840	0.5880	0.5000	-0.177000	4.57e-01	2.20e-03	4.70e-04	6.87e-03	7.74e-01	4.53e-04	3.19e-03	2.68e-01
REACTOME COMPLEMENT CASCADE	10	1.29e-04	9.05e-04	1.150	-0.56500	0.3000	-0.54200	0.52600	-0.51700	0.2660	0.1200	-0.024100	1.02e-03	8.59e-02	1.66e-03	2.32e-03	2.56e-03	1.36e-01	5.03e-01	8.66e-01
REACTOME PYRUVATE METABOLISM	16	1.90e-08	3.20e-07	1.150	0.61100	-0.2360	0.14400	-0.58000	0.57400	0.2230	-0.3470	0.199000	4.02e-05	8.32e-02	3.13e-01	2.73e-05	8.19e-05	1.16e-01	1.29e-02	1.54e-01
REACTOME PEPTIDE CHAIN ELONGATION	67	1.21e-44	1.42e-42	1.070	-0.50600	0.2480	-0.12600	-0.24900	-0.46900	0.1830	0.6840	-0.187000	2.53e-14	2.84e-04	8.20e-02	5.29e-04	6.63e-13	8.73e-03	1.24e-23	4.40e-03
REACTOME NCAM1 INTERACTIONS	15	5.21e-07	5.58e-06	1.040	-0.17500	0.4690	-0.11600	0.68900	-0.29000	0.3660	-0.1550	0.316000	1.72e-01	9.89e-04	3.95e-01	1.05e-06	3.30e-02	1.13e-02	2.81e-01	2.69e-02
REACTOME MITOCHONDRIAL PROTEIN IMPORT	42	1.44e-15	3.57e-14	0.942	0.33900	-0.1670	0.12200	-0.62000	0.47900	0.1290	-0.3150	0.000192	3.76e-04	4.67e-02	1.68e-01	3.97e-13	1.31e-07	1.52e-01	2.63e-04	9.56e-01
REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	42	4.42e-18	1.60e-16	0.939	-0.40700	0.1880	0.04640	-0.17300	-0.33100	0.2700	0.6510	-0.206000	1.02e-06	3.04e-02	4.45e-01	7.81e-02	3.68e-05	1.80e-03	3.46e-14	1.34e-02
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	89	2.20e-41	2.07e-39	0.907	-0.41000	0.2360	-0.09690	-0.20500	-0.39800	0.1790	0.5750	-0.158000	6.71e-13	6.56e-05	1.18e-01	1.02e-03	1.75e-12	3.17e-03	3.49e-22	5.25e-03
REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	83	5.85e-38	3.44e-36	0.882	-0.40700	0.1770	-0.07080	-0.28500	-0.37800	0.1720	0.5470	-0.151000	5.34e-12	3.99e-03	2.86e-01	7.39e-06	8.96e-11	6.20e-03	5.52e-19	9.65e-03
REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION	86	2.99e-38	2.01e-36	0.878	-0.36100	0.1740	-0.03610	-0.22600	-0.29500	0.2160	0.6330	-0.156000	3.86e-10	3.90e-03	6.12e-01	3.56e-04	1.68e-07	4.33e-04	1.00e-25	6.62e-03
REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	16	2.14e-03	1.11e-02	0.860	0.32700	-0.2880	-0.03710	-0.45900	0.48000	-0.0355	-0.2600	-0.194000	3.47e-02	3.48e-02	7.59e-01	9.20e-04	1.09e-03	7.58e-01	6.26e-02	1.45e-01
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	49	3.45e-17	1.08e-15	0.838	-0.30200	0.1600	0.05330	-0.15800	-0.24100	0.2790	0.6280	-0.164000	6.94e-05	4.59e-02	3.85e-01	8.08e-02	9.23e-04	5.04e-04	2.96e-15	3.25e-02
REACTOME ADP SIGNALLING THROUGH P2RY1	11	1.30e-03	7.11e-03	0.827	-0.31600	-0.3970	-0.15500	-0.50100	0.00543	-0.3550	-0.1540	-0.052800	4.64e-02	1.61e-02	3.36e-01	2.73e-03	9.33e-01	2.88e-02	3.59e-01	7.25e-01
REACTOME REGULATION OF KIT SIGNALING	12	9.68e-03	4.04e-02	0.825	-0.30100	0.0730	-0.67700	0.00997	-0.28000	-0.1470	0.1410	0.076200	2.64e-01	9.42e-01	2.00e-04	9.41e-01	4.21e-01	2.18e-01	6.10e-01	6.95e-01
REACTOME SIGNALING BY HIPPO	15	5.66e-04	3.46e-03	0.816	-0.18400	0.1240	0.03270	0.12000	-0.45300	0.0845	-0.1430	-0.608000	1.53e-01	3.91e-01	8.46e-01	3.83e-01	1.16e-03	5.84e-01	3.20e-01	1.32e-05
REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	85	1.08e-30	5.66e-29	0.803	-0.38600	0.1850	-0.08300	-0.20200	-0.34200	0.1450	0.5100	-0.122000	3.25e-11	2.32e-03	1.98e-01	1.63e-03	2.26e-09	2.11e-02	5.15e-17	3.29e-02
REACTOME EXTRACELLULAR MATRIX ORGANIZATION	32	1.02e-09	2.18e-08	0.802	-0.18600	0.2030	-0.23100	0.57600	-0.25200	0.2150	-0.1220	0.240000	6.16e-02	4.18e-02	2.21e-02	7.33e-10	7.89e-03	3.49e-02	1.97e-01	1.62e-02
REACTOME COLLAGEN FORMATION	27	1.03e-07	1.39e-06	0.782	-0.18400	0.1820	-0.20000	0.54600	-0.16200	0.2390	-0.0968	0.338000	9.74e-02	9.43e-02	7.59e-02	6.47e-08	1.13e-01	3.14e-02	3.39e-01	1.83e-03
REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	11	6.33e-03	2.95e-02	0.781	-0.39900	-0.3230	-0.47400	-0.16100	-0.09910	-0.2500	-0.0190	-0.150000	4.23e-02	1.09e-02	1.28e-02	3.67e-01	8.39e-01	7.49e-02	9.94e-01	5.79e-01
REACTOME TRANSLATION	124	5.12e-40	4.02e-38	0.756	-0.28900	0.1730	-0.05540	-0.15200	-0.24100	0.2360	0.5510	-0.117000	9.86e-10	5.81e-04	2.88e-01	4.36e-03	2.14e-07	3.67e-06	8.98e-28	1.34e-02
REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	11	5.95e-03	2.83e-02	0.751	-0.31700	-0.4050	-0.16300	-0.44800	0.13100	-0.2300	-0.0505	-0.015700	4.56e-02	1.41e-02	3.10e-01	7.33e-03	5.14e-01	1.52e-01	7.60e-01	9.00e-01
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	11	3.88e-01	5.64e-01	0.748	-0.25700	0.2400	-0.32700	0.24100	-0.28100	0.4200	-0.0937	0.082300	7.90e-01	1.82e-01	1.39e-01	4.56e-01	7.95e-01	6.55e-02	3.69e-01	7.28e-01
REACTOME G PROTEIN ACTIVATION	10	1.89e-03	1.00e-02	0.745	-0.44700	-0.2780	0.01060	-0.36300	-0.04330	-0.3450	0.0151	-0.156000	8.51e-03	1.07e-01	9.75e-01	3.88e-02	7.23e-01	4.29e-02	9.37e-01	3.51e-01
REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	13	2.17e-02	7.86e-02	0.744	-0.51000	0.2560	0.00955	0.11700	-0.43300	0.1170	0.0769	0.083600	6.79e-04	9.49e-02	9.77e-01	4.29e-01	3.75e-03	4.70e-01	6.26e-01	6.02e-01
REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	10	1.80e-02	6.62e-02	0.742	-0.18300	-0.2860	-0.23200	-0.45100	-0.07890	-0.4070	-0.0736	0.004020	2.44e-01	9.72e-02	1.74e-01	1.01e-02	5.80e-01	1.72e-02	6.73e-01	9.96e-01
REACTOME GLUCONEOGENESIS	20	7.01e-06	5.90e-05	0.740	0.21400	0.1360	0.41600	-0.23000	0.26400	0.3100	-0.0734	-0.296000	2.39e-02	3.00e-01	4.27e-05	8.16e-02	1.94e-02	1.93e-02	4.32e-01	3.69e-02
REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	18	1.01e-02	4.13e-02	0.740	-0.31800	-0.2070	-0.40400	0.16000	-0.35400	-0.2750	-0.0997	-0.057600	6.66e-02	1.08e-01	4.52e-03	3.99e-01	3.42e-02	4.06e-02	6.46e-01	8.68e-01
REACTOME METABOLISM OF POLYAMINES	13	2.91e-02	1.01e-01	0.739	0.43900	0.2680	0.32900	-0.12800	0.06030	0.1070	0.3440	0.155000	1.88e-02	5.01e-02	5.11e-02	6.30e-01	9.23e-01	3.79e-01	6.14e-02	4.41e-01
REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	10	9.02e-04	5.44e-03	0.735	-0.35300	-0.2600	0.00381	-0.45300	0.14400	-0.3180	0.0962	-0.109000	3.53e-02	1.32e-01	9.94e-01	9.76e-03	4.86e-01	6.19e-02	5.92e-01	5.10e-01
REACTOME TRAFFICKING OF AMPA RECEPTORS	16	6.94e-03	3.14e-02	0.716	0.04630	0.4720	0.00632	0.26500	-0.30100	0.1350	-0.1210	-0.306000	7.72e-01	3.16e-04	7.36e-01	5.82e-02	2.89e-02	3.78e-01	2.56e-01	4.27e-02
REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	10	5.57e-02	1.67e-01	0.711	-0.23700	0.0242	-0.22600	-0.12900	-0.44900	-0.3420	-0.2150	-0.130000	1.44e-01	8.98e-01	1.85e-01	4.71e-01	8.56e-03	4.45e-02	2.23e-01	4.32e-01
REACTOME CYTOSOLIC TRNA AMINOACYLATION	22	1.12e-03	6.40e-03	0.711	0.14300	0.2420	0.26200	0.06530	0.32900	0.3790	0.3160	0.044700	3.35e-01	4.05e-02	2.84e-02	5.57e-01	1.00e-02	1.50e-03	8.58e-03	7.32e-01
REACTOME SIGNAL AMPLIFICATION	14	1.16e-03	6.40e-03	0.707	-0.32600	-0.2720	-0.14700	-0.36200	-0.14000	-0.3710	-0.0915	-0.021500	2.06e-02	6.21e-02	3.01e-01	1.47e-02	2.87e-01	1.00e-02	5.36e-01	8.56e-01
REACTOME STRIATED MUSCLE CONTRACTION	22	2.95e-04	1.99e-03	0.705	0.36300	-0.2490	0.01040	-0.31200	0.30600	0.1550	-0.0317	0.295000	5.55e-03	3.22e-02	9.64e-01	8.65e-03	1.71e-02	2.07e-01	7.84e-01	1.25e-02
REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	22	2.68e-02	9.47e-02	0.696	-0.53500	-0.2450	-0.14900	0.08230	-0.25600	-0.0191	0.1410	-0.153000	1.12e-02	3.28e-02	2.79e-01	7.90e-01	9.97e-01	6.68e-01	3.87e-01	2.62e-01
REACTOME INTERFERON GAMMA SIGNALING	32	2.92e-03	1.46e-02	0.694	-0.38300	0.3590	0.06340	0.15900	-0.20700	0.2330	0.1130	-0.260000	3.78e-03	1.24e-03	5.18e-01	2.79e-01	2.94e-01	1.09e-02	2.68e-01	2.56e-02
REACTOME PLATELET AGGREGATION PLUG FORMATION	19	1.83e-02	6.66e-02	0.689	-0.28000	-0.2240	-0.39900	0.13100	-0.29100	-0.2640	-0.1250	-0.018700	1.06e-01	7.43e-02	3.85e-03	5.18e-01	8.93e-02	4.22e-02	4.86e-01	9.02e-01
REACTOME G PROTEIN BETA GAMMA SIGNALLING	12	1.76e-02	6.54e-02	0.682	-0.25500	-0.3750	-0.19800	-0.37600	0.14000	-0.2190	-0.0898	-0.056100	8.68e-02	1.76e-02	2.01e-01	1.90e-02	4.59e-01	1.55e-01	5.75e-01	6.98e-01
REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS	20	5.31e-02	1.64e-01	0.667	-0.00264	-0.2020	-0.34700	-0.05650	-0.06230	-0.4270	-0.2870	0.110000	9.91e-01	1.43e-01	1.37e-02	8.97e-01	7.90e-01	8.21e-03	2.66e-02	3.37e-01
REACTOME INFLUENZA LIFE CYCLE	115	1.69e-26	7.24e-25	0.667	-0.30500	0.1910	-0.04310	-0.15400	-0.28400	0.1710	0.4190	-0.060200	7.70e-10	5.12e-04	3.13e-01	5.20e-03	9.80e-09	1.81e-03	1.62e-15	2.80e-01
REACTOME SIGNALING BY NOTCH3	12	3.04e-01	4.82e-01	0.663	-0.21700	-0.1990	-0.15300	-0.26900	-0.26100	-0.3810	-0.0881	-0.191000	2.93e-01	2.72e-01	5.20e-01	2.62e-01	1.96e-01	8.41e-02	4.44e-01	1.60e-01
REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	15	4.15e-02	1.35e-01	0.663	-0.42500	-0.0606	0.09830	-0.07730	0.01170	0.4160	0.2570	-0.009140	5.08e-03	6.70e-01	5.26e-01	6.16e-01	9.16e-01	5.33e-03	8.75e-02	9.23e-01

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Results (complete table)

Click HERE to show results for all gene sets

Complete results

set	setSize	pMANOVA	p.adjustMANOVA	s.dist	s.de1	s.de2	s.de3	s.de4	s.de5	s.de6	s.de7	s.de8	p.de1	p.de2	p.de3	p.de4	p.de5	p.de6	p.de7	p.de8
REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	12	4.51e-16	1.25e-14	1.700	0.823000	-0.03810	0.530000	-9.13e-01	8.06e-01	0.121000	-0.664000	-6.61e-02	1.24e-06	8.01e-01	9.50e-04	9.82e-09	1.29e-06	4.73e-01	3.90e-05	6.52e-01
REACTOME CITRIC ACID CYCLE TCA CYCLE	19	8.66e-25	3.40e-23	1.610	0.569000	-0.36400	0.375000	-8.60e-01	7.89e-01	0.209000	-0.762000	1.46e-01	3.30e-05	3.72e-03	3.45e-03	1.14e-11	2.59e-09	1.08e-01	2.97e-09	2.60e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	13	1.04e-13	2.44e-12	1.560	0.532000	-0.61900	0.281000	-7.10e-01	8.13e-01	0.183000	-0.654000	2.46e-01	1.37e-03	4.56e-05	7.12e-02	3.60e-06	3.82e-07	2.48e-01	2.51e-05	1.11e-01
REACTOME RESPIRATORY ELECTRON TRANSPORT	59	2.97e-61	4.66e-59	1.440	0.643000	-0.04320	0.115000	-8.43e-01	6.92e-01	0.077200	-0.671000	3.86e-02	9.05e-17	5.29e-01	1.28e-01	7.79e-32	5.23e-20	3.27e-01	3.38e-20	6.35e-01
REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	73	3.66e-75	8.63e-73	1.420	0.649000	-0.03560	0.182000	-8.22e-01	6.97e-01	0.103000	-0.628000	2.30e-02	1.00e-20	5.61e-01	6.26e-03	3.96e-37	1.02e-24	1.35e-01	9.47e-22	7.77e-01
REACTOME TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT	107	6.02e-101	2.84e-98	1.360	0.599000	-0.12100	0.195000	-7.88e-01	6.81e-01	0.150000	-0.571000	5.77e-02	2.70e-25	2.14e-02	3.78e-04	2.15e-49	6.99e-34	7.17e-03	5.79e-26	3.19e-01
REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	11	8.02e-08	1.11e-06	1.330	0.590000	-0.32100	0.124000	-6.39e-01	6.93e-01	0.290000	-0.522000	2.38e-01	1.02e-03	5.15e-02	4.75e-01	1.28e-04	7.28e-05	8.75e-02	1.97e-03	1.56e-01
REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	38	7.68e-30	3.62e-28	1.290	0.509000	-0.29700	0.240000	-7.24e-01	6.60e-01	0.221000	-0.482000	1.20e-01	1.75e-07	7.93e-04	8.72e-03	6.61e-16	2.43e-12	1.66e-02	1.12e-07	1.92e-01
REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	11	7.59e-06	6.27e-05	1.210	0.154000	0.50900	0.585000	4.45e-01	6.84e-02	0.588000	0.500000	-1.77e-01	4.57e-01	2.20e-03	4.70e-04	6.87e-03	7.74e-01	4.53e-04	3.19e-03	2.68e-01
REACTOME COMPLEMENT CASCADE	10	1.29e-04	9.05e-04	1.150	-0.565000	0.30000	-0.542000	5.26e-01	-5.17e-01	0.266000	0.120000	-2.41e-02	1.02e-03	8.59e-02	1.66e-03	2.32e-03	2.56e-03	1.36e-01	5.03e-01	8.66e-01
REACTOME PYRUVATE METABOLISM	16	1.90e-08	3.20e-07	1.150	0.611000	-0.23600	0.144000	-5.80e-01	5.74e-01	0.223000	-0.347000	1.99e-01	4.02e-05	8.32e-02	3.13e-01	2.73e-05	8.19e-05	1.16e-01	1.29e-02	1.54e-01
REACTOME PEPTIDE CHAIN ELONGATION	67	1.21e-44	1.42e-42	1.070	-0.506000	0.24800	-0.126000	-2.49e-01	-4.69e-01	0.183000	0.684000	-1.87e-01	2.53e-14	2.84e-04	8.20e-02	5.29e-04	6.63e-13	8.73e-03	1.24e-23	4.40e-03
REACTOME NCAM1 INTERACTIONS	15	5.21e-07	5.58e-06	1.040	-0.175000	0.46900	-0.116000	6.89e-01	-2.90e-01	0.366000	-0.155000	3.16e-01	1.72e-01	9.89e-04	3.95e-01	1.05e-06	3.30e-02	1.13e-02	2.81e-01	2.69e-02
REACTOME MITOCHONDRIAL PROTEIN IMPORT	42	1.44e-15	3.57e-14	0.942	0.339000	-0.16700	0.122000	-6.20e-01	4.79e-01	0.129000	-0.315000	1.92e-04	3.76e-04	4.67e-02	1.68e-01	3.97e-13	1.31e-07	1.52e-01	2.63e-04	9.56e-01
REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	42	4.42e-18	1.60e-16	0.939	-0.407000	0.18800	0.046400	-1.73e-01	-3.31e-01	0.270000	0.651000	-2.06e-01	1.02e-06	3.04e-02	4.45e-01	7.81e-02	3.68e-05	1.80e-03	3.46e-14	1.34e-02
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	89	2.20e-41	2.07e-39	0.907	-0.410000	0.23600	-0.096900	-2.05e-01	-3.98e-01	0.179000	0.575000	-1.58e-01	6.71e-13	6.56e-05	1.18e-01	1.02e-03	1.75e-12	3.17e-03	3.49e-22	5.25e-03
REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	83	5.85e-38	3.44e-36	0.882	-0.407000	0.17700	-0.070800	-2.85e-01	-3.78e-01	0.172000	0.547000	-1.51e-01	5.34e-12	3.99e-03	2.86e-01	7.39e-06	8.96e-11	6.20e-03	5.52e-19	9.65e-03
REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION	86	2.99e-38	2.01e-36	0.878	-0.361000	0.17400	-0.036100	-2.26e-01	-2.95e-01	0.216000	0.633000	-1.56e-01	3.86e-10	3.90e-03	6.12e-01	3.56e-04	1.68e-07	4.33e-04	1.00e-25	6.62e-03
REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	16	2.14e-03	1.11e-02	0.860	0.327000	-0.28800	-0.037100	-4.59e-01	4.80e-01	-0.035500	-0.260000	-1.94e-01	3.47e-02	3.48e-02	7.59e-01	9.20e-04	1.09e-03	7.58e-01	6.26e-02	1.45e-01
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	49	3.45e-17	1.08e-15	0.838	-0.302000	0.16000	0.053300	-1.58e-01	-2.41e-01	0.279000	0.628000	-1.64e-01	6.94e-05	4.59e-02	3.85e-01	8.08e-02	9.23e-04	5.04e-04	2.96e-15	3.25e-02
REACTOME ADP SIGNALLING THROUGH P2RY1	11	1.30e-03	7.11e-03	0.827	-0.316000	-0.39700	-0.155000	-5.01e-01	5.43e-03	-0.355000	-0.154000	-5.28e-02	4.64e-02	1.61e-02	3.36e-01	2.73e-03	9.33e-01	2.88e-02	3.59e-01	7.25e-01
REACTOME REGULATION OF KIT SIGNALING	12	9.68e-03	4.04e-02	0.825	-0.301000	0.07300	-0.677000	9.97e-03	-2.80e-01	-0.147000	0.141000	7.62e-02	2.64e-01	9.42e-01	2.00e-04	9.41e-01	4.21e-01	2.18e-01	6.10e-01	6.95e-01
REACTOME SIGNALING BY HIPPO	15	5.66e-04	3.46e-03	0.816	-0.184000	0.12400	0.032700	1.20e-01	-4.53e-01	0.084500	-0.143000	-6.08e-01	1.53e-01	3.91e-01	8.46e-01	3.83e-01	1.16e-03	5.84e-01	3.20e-01	1.32e-05
REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	85	1.08e-30	5.66e-29	0.803	-0.386000	0.18500	-0.083000	-2.02e-01	-3.42e-01	0.145000	0.510000	-1.22e-01	3.25e-11	2.32e-03	1.98e-01	1.63e-03	2.26e-09	2.11e-02	5.15e-17	3.29e-02
REACTOME EXTRACELLULAR MATRIX ORGANIZATION	32	1.02e-09	2.18e-08	0.802	-0.186000	0.20300	-0.231000	5.76e-01	-2.52e-01	0.215000	-0.122000	2.40e-01	6.16e-02	4.18e-02	2.21e-02	7.33e-10	7.89e-03	3.49e-02	1.97e-01	1.62e-02
REACTOME COLLAGEN FORMATION	27	1.03e-07	1.39e-06	0.782	-0.184000	0.18200	-0.200000	5.46e-01	-1.62e-01	0.239000	-0.096800	3.38e-01	9.74e-02	9.43e-02	7.59e-02	6.47e-08	1.13e-01	3.14e-02	3.39e-01	1.83e-03
REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	11	6.33e-03	2.95e-02	0.781	-0.399000	-0.32300	-0.474000	-1.61e-01	-9.91e-02	-0.250000	-0.019000	-1.50e-01	4.23e-02	1.09e-02	1.28e-02	3.67e-01	8.39e-01	7.49e-02	9.94e-01	5.79e-01
REACTOME TRANSLATION	124	5.12e-40	4.02e-38	0.756	-0.289000	0.17300	-0.055400	-1.52e-01	-2.41e-01	0.236000	0.551000	-1.17e-01	9.86e-10	5.81e-04	2.88e-01	4.36e-03	2.14e-07	3.67e-06	8.98e-28	1.34e-02
REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	11	5.95e-03	2.83e-02	0.751	-0.317000	-0.40500	-0.163000	-4.48e-01	1.31e-01	-0.230000	-0.050500	-1.57e-02	4.56e-02	1.41e-02	3.10e-01	7.33e-03	5.14e-01	1.52e-01	7.60e-01	9.00e-01
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	11	3.88e-01	5.64e-01	0.748	-0.257000	0.24000	-0.327000	2.41e-01	-2.81e-01	0.420000	-0.093700	8.23e-02	7.90e-01	1.82e-01	1.39e-01	4.56e-01	7.95e-01	6.55e-02	3.69e-01	7.28e-01
REACTOME G PROTEIN ACTIVATION	10	1.89e-03	1.00e-02	0.745	-0.447000	-0.27800	0.010600	-3.63e-01	-4.33e-02	-0.345000	0.015100	-1.56e-01	8.51e-03	1.07e-01	9.75e-01	3.88e-02	7.23e-01	4.29e-02	9.37e-01	3.51e-01
REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	13	2.17e-02	7.86e-02	0.744	-0.510000	0.25600	0.009550	1.17e-01	-4.33e-01	0.117000	0.076900	8.36e-02	6.79e-04	9.49e-02	9.77e-01	4.29e-01	3.75e-03	4.70e-01	6.26e-01	6.02e-01
REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	10	1.80e-02	6.62e-02	0.742	-0.183000	-0.28600	-0.232000	-4.51e-01	-7.89e-02	-0.407000	-0.073600	4.02e-03	2.44e-01	9.72e-02	1.74e-01	1.01e-02	5.80e-01	1.72e-02	6.73e-01	9.96e-01
REACTOME GLUCONEOGENESIS	20	7.01e-06	5.90e-05	0.740	0.214000	0.13600	0.416000	-2.30e-01	2.64e-01	0.310000	-0.073400	-2.96e-01	2.39e-02	3.00e-01	4.27e-05	8.16e-02	1.94e-02	1.93e-02	4.32e-01	3.69e-02
REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	18	1.01e-02	4.13e-02	0.740	-0.318000	-0.20700	-0.404000	1.60e-01	-3.54e-01	-0.275000	-0.099700	-5.76e-02	6.66e-02	1.08e-01	4.52e-03	3.99e-01	3.42e-02	4.06e-02	6.46e-01	8.68e-01
REACTOME METABOLISM OF POLYAMINES	13	2.91e-02	1.01e-01	0.739	0.439000	0.26800	0.329000	-1.28e-01	6.03e-02	0.107000	0.344000	1.55e-01	1.88e-02	5.01e-02	5.11e-02	6.30e-01	9.23e-01	3.79e-01	6.14e-02	4.41e-01
REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	10	9.02e-04	5.44e-03	0.735	-0.353000	-0.26000	0.003810	-4.53e-01	1.44e-01	-0.318000	0.096200	-1.09e-01	3.53e-02	1.32e-01	9.94e-01	9.76e-03	4.86e-01	6.19e-02	5.92e-01	5.10e-01
REACTOME TRAFFICKING OF AMPA RECEPTORS	16	6.94e-03	3.14e-02	0.716	0.046300	0.47200	0.006320	2.65e-01	-3.01e-01	0.135000	-0.121000	-3.06e-01	7.72e-01	3.16e-04	7.36e-01	5.82e-02	2.89e-02	3.78e-01	2.56e-01	4.27e-02
REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	10	5.57e-02	1.67e-01	0.711	-0.237000	0.02420	-0.226000	-1.29e-01	-4.49e-01	-0.342000	-0.215000	-1.30e-01	1.44e-01	8.98e-01	1.85e-01	4.71e-01	8.56e-03	4.45e-02	2.23e-01	4.32e-01
REACTOME CYTOSOLIC TRNA AMINOACYLATION	22	1.12e-03	6.40e-03	0.711	0.143000	0.24200	0.262000	6.53e-02	3.29e-01	0.379000	0.316000	4.47e-02	3.35e-01	4.05e-02	2.84e-02	5.57e-01	1.00e-02	1.50e-03	8.58e-03	7.32e-01
REACTOME SIGNAL AMPLIFICATION	14	1.16e-03	6.40e-03	0.707	-0.326000	-0.27200	-0.147000	-3.62e-01	-1.40e-01	-0.371000	-0.091500	-2.15e-02	2.06e-02	6.21e-02	3.01e-01	1.47e-02	2.87e-01	1.00e-02	5.36e-01	8.56e-01
REACTOME STRIATED MUSCLE CONTRACTION	22	2.95e-04	1.99e-03	0.705	0.363000	-0.24900	0.010400	-3.12e-01	3.06e-01	0.155000	-0.031700	2.95e-01	5.55e-03	3.22e-02	9.64e-01	8.65e-03	1.71e-02	2.07e-01	7.84e-01	1.25e-02
REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	22	2.68e-02	9.47e-02	0.696	-0.535000	-0.24500	-0.149000	8.23e-02	-2.56e-01	-0.019100	0.141000	-1.53e-01	1.12e-02	3.28e-02	2.79e-01	7.90e-01	9.97e-01	6.68e-01	3.87e-01	2.62e-01
REACTOME INTERFERON GAMMA SIGNALING	32	2.92e-03	1.46e-02	0.694	-0.383000	0.35900	0.063400	1.59e-01	-2.07e-01	0.233000	0.113000	-2.60e-01	3.78e-03	1.24e-03	5.18e-01	2.79e-01	2.94e-01	1.09e-02	2.68e-01	2.56e-02
REACTOME PLATELET AGGREGATION PLUG FORMATION	19	1.83e-02	6.66e-02	0.689	-0.280000	-0.22400	-0.399000	1.31e-01	-2.91e-01	-0.264000	-0.125000	-1.87e-02	1.06e-01	7.43e-02	3.85e-03	5.18e-01	8.93e-02	4.22e-02	4.86e-01	9.02e-01
REACTOME G PROTEIN BETA GAMMA SIGNALLING	12	1.76e-02	6.54e-02	0.682	-0.255000	-0.37500	-0.198000	-3.76e-01	1.40e-01	-0.219000	-0.089800	-5.61e-02	8.68e-02	1.76e-02	2.01e-01	1.90e-02	4.59e-01	1.55e-01	5.75e-01	6.98e-01
REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS	20	5.31e-02	1.64e-01	0.667	-0.002640	-0.20200	-0.347000	-5.65e-02	-6.23e-02	-0.427000	-0.287000	1.10e-01	9.91e-01	1.43e-01	1.37e-02	8.97e-01	7.90e-01	8.21e-03	2.66e-02	3.37e-01
REACTOME INFLUENZA LIFE CYCLE	115	1.69e-26	7.24e-25	0.667	-0.305000	0.19100	-0.043100	-1.54e-01	-2.84e-01	0.171000	0.419000	-6.02e-02	7.70e-10	5.12e-04	3.13e-01	5.20e-03	9.80e-09	1.81e-03	1.62e-15	2.80e-01
REACTOME SIGNALING BY NOTCH3	12	3.04e-01	4.82e-01	0.663	-0.217000	-0.19900	-0.153000	-2.69e-01	-2.61e-01	-0.381000	-0.088100	-1.91e-01	2.93e-01	2.72e-01	5.20e-01	2.62e-01	1.96e-01	8.41e-02	4.44e-01	1.60e-01
REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	15	4.15e-02	1.35e-01	0.663	-0.425000	-0.06060	0.098300	-7.73e-02	1.17e-02	0.416000	0.257000	-9.14e-03	5.08e-03	6.70e-01	5.26e-01	6.16e-01	9.16e-01	5.33e-03	8.75e-02	9.23e-01
REACTOME P75NTR SIGNALS VIA NFKB	10	2.14e-01	4.04e-01	0.654	-0.254000	0.05580	-0.029200	8.93e-02	-2.31e-01	0.019400	0.439000	3.23e-01	2.14e-01	3.61e-01	8.60e-01	9.25e-01	1.16e-01	5.46e-01	2.42e-02	1.27e-01
REACTOME CALNEXIN CALRETICULIN CYCLE	11	9.18e-02	2.40e-01	0.653	-0.498000	0.14900	0.011500	7.27e-02	-3.69e-01	0.058700	0.024600	1.09e-01	2.26e-03	3.76e-01	9.69e-01	6.45e-01	2.21e-02	7.54e-01	8.90e-01	5.26e-01
REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	20	1.02e-03	6.03e-03	0.651	0.078000	0.47200	0.314000	-5.61e-02	7.49e-02	0.176000	0.012600	-2.40e-01	6.85e-01	1.31e-04	1.21e-02	6.70e-01	6.62e-01	1.70e-01	9.27e-01	4.47e-02
REACTOME GLUTATHIONE CONJUGATION	12	1.83e-01	3.66e-01	0.640	0.371000	-0.18100	0.314000	-4.91e-02	3.57e-01	-0.055300	0.085300	-4.07e-02	3.62e-02	2.50e-01	5.22e-02	7.75e-01	3.84e-02	6.95e-01	6.03e-01	7.72e-01
REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	16	9.54e-03	4.01e-02	0.635	-0.165000	-0.29900	-0.191000	-2.61e-01	-1.65e-01	-0.371000	-0.119000	4.56e-02	2.20e-01	3.75e-02	1.82e-01	5.23e-02	2.15e-01	2.73e-03	6.42e-01	7.80e-01
REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	11	3.69e-01	5.43e-01	0.630	-0.327000	-0.09640	-0.152000	-8.30e-02	-3.83e-01	-0.233000	-0.169000	-1.44e-01	7.10e-02	5.91e-01	5.24e-01	8.56e-01	8.44e-02	2.89e-01	2.13e-01	2.65e-01
REACTOME SIGNALING BY NOTCH2	12	4.07e-01	5.79e-01	0.623	-0.228000	-0.04220	-0.143000	-1.96e-01	-3.59e-01	-0.346000	-0.073700	-1.49e-01	2.61e-01	8.10e-01	5.62e-01	5.27e-01	4.69e-02	1.34e-01	4.97e-01	2.53e-01
REACTOME SIGNALING BY NOTCH4	12	4.32e-01	5.97e-01	0.622	-0.223000	-0.19700	-0.083200	-1.77e-01	-3.24e-01	-0.387000	-0.033600	-6.11e-02	2.76e-01	2.77e-01	8.26e-01	6.13e-01	8.11e-02	7.71e-02	6.60e-01	5.43e-01
REACTOME REGULATION OF IFNG SIGNALING	12	2.32e-01	4.21e-01	0.619	-0.207000	0.23400	0.124000	3.72e-02	-1.20e-01	0.216000	0.434000	1.41e-01	1.24e-01	2.04e-01	5.18e-01	7.46e-01	8.01e-01	6.49e-02	2.07e-02	4.54e-01
REACTOME RAP1 SIGNALLING	12	4.54e-02	1.44e-01	0.614	-0.356000	-0.00760	-0.210000	-7.19e-02	-3.58e-01	-0.231000	-0.060800	1.24e-01	2.01e-02	9.52e-01	1.76e-01	6.68e-01	2.01e-02	1.34e-01	7.02e-01	4.48e-01
REACTOME SIGNAL ATTENUATION	10	8.26e-02	2.25e-01	0.610	0.136000	-0.06690	-0.396000	2.20e-01	-1.99e-01	-0.279000	0.117000	1.15e-01	5.42e-01	6.92e-01	2.13e-02	1.99e-01	2.20e-01	9.95e-02	5.14e-01	5.22e-01
REACTOME TRAF6 MEDIATED NFKB ACTIVATION	13	1.73e-02	6.52e-02	0.608	-0.293000	-0.19900	-0.196000	-1.50e-01	3.03e-02	-0.145000	0.268000	3.00e-01	4.30e-02	1.87e-01	1.88e-01	3.37e-01	9.46e-01	3.18e-01	8.59e-02	5.11e-02
REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	22	8.48e-03	3.66e-02	0.606	0.026700	-0.30400	-0.092900	-2.21e-01	1.15e-01	-0.364000	-0.203000	-1.74e-01	6.36e-01	5.53e-03	8.65e-01	3.03e-02	4.52e-01	4.96e-03	2.04e-01	1.42e-01
REACTOME GPVI MEDIATED ACTIVATION CASCADE	19	1.49e-01	3.26e-01	0.606	-0.268000	0.09670	-0.370000	1.06e-01	-2.35e-01	0.199000	-0.016600	2.07e-01	2.42e-01	6.43e-01	6.47e-03	6.31e-01	3.88e-01	2.08e-01	8.70e-01	1.37e-01
REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	13	2.66e-01	4.49e-01	0.602	-0.206000	0.28400	0.262000	-7.00e-03	-5.73e-02	0.306000	0.265000	-6.41e-02	1.41e-01	6.43e-02	9.31e-02	9.83e-01	6.22e-01	4.96e-02	8.92e-02	6.48e-01
REACTOME TRNA AMINOACYLATION	39	1.97e-05	1.47e-04	0.599	0.106000	0.32800	0.268000	-4.11e-02	2.31e-01	0.287000	0.160000	-7.37e-02	3.86e-01	2.08e-04	2.89e-03	6.71e-01	1.94e-02	1.48e-03	7.72e-02	3.68e-01
REACTOME GPCR LIGAND BINDING	44	4.63e-04	2.95e-03	0.591	-0.002280	-0.26000	-0.228000	-1.21e-01	2.66e-02	-0.390000	-0.245000	-4.98e-02	5.91e-01	1.70e-03	6.09e-02	1.98e-01	7.12e-01	6.89e-05	1.91e-02	7.88e-01
REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	11	1.54e-01	3.28e-01	0.586	0.111000	-0.14100	0.326000	-8.18e-02	1.24e-01	0.104000	0.265000	3.19e-01	6.23e-01	3.89e-01	5.28e-02	6.38e-01	5.40e-01	5.58e-01	1.19e-01	5.55e-02
REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	41	7.09e-08	1.08e-06	0.584	0.216000	0.25400	0.029400	-5.06e-02	7.50e-02	0.446000	0.136000	-5.68e-02	1.47e-02	3.72e-03	7.56e-01	5.90e-01	3.82e-01	4.33e-07	8.17e-02	6.45e-01
REACTOME PLATELET SENSITIZATION BY LDL	12	3.48e-01	5.29e-01	0.582	-0.213000	-0.23100	-0.070000	-1.39e-01	-2.42e-01	-0.185000	-0.249000	-2.47e-01	3.25e-01	1.59e-01	6.51e-01	4.16e-01	2.48e-01	2.46e-01	1.39e-01	1.25e-01
REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	43	1.81e-08	3.20e-07	0.581	0.214000	0.23700	0.011200	-4.32e-02	7.73e-02	0.449000	0.154000	-4.54e-02	1.42e-02	5.53e-03	9.23e-01	6.42e-01	3.63e-01	1.86e-07	4.66e-02	7.30e-01
REACTOME EXTENSION OF TELOMERES	15	1.17e-01	2.79e-01	0.581	-0.194000	0.14200	0.226000	-8.72e-02	-2.64e-01	0.013900	0.320000	-2.20e-01	2.18e-01	3.58e-01	1.48e-01	4.90e-01	3.17e-02	9.88e-01	3.09e-02	1.37e-01
REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	20	1.14e-03	6.40e-03	0.581	-0.296000	-0.21800	-0.017000	-2.29e-01	-1.06e-01	-0.360000	0.091300	-6.40e-03	2.79e-02	8.09e-02	8.61e-01	7.48e-02	5.22e-01	3.63e-03	6.20e-01	9.28e-01
REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	44	6.66e-09	1.31e-07	0.577	0.264000	0.23100	0.041000	-5.06e-02	8.15e-02	0.417000	0.144000	-6.31e-02	2.19e-03	6.36e-03	6.45e-01	5.77e-01	3.35e-01	1.02e-06	5.85e-02	5.67e-01
REACTOME LAGGING STRAND SYNTHESIS	10	4.11e-01	5.80e-01	0.576	-0.257000	0.17500	0.140000	3.83e-02	-2.97e-01	0.029400	0.354000	1.53e-02	2.39e-01	4.36e-01	4.63e-01	9.60e-01	1.23e-01	7.55e-01	2.77e-02	9.54e-01
REACTOME GLUCOSE METABOLISM	45	6.97e-07	7.29e-06	0.573	0.199000	0.18700	0.291000	-3.30e-02	2.12e-01	0.318000	0.047400	-1.39e-01	1.14e-02	2.73e-02	8.52e-05	7.27e-01	1.09e-02	2.07e-04	6.44e-01	1.27e-01
REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	13	1.51e-02	5.88e-02	0.564	-0.163000	0.08310	-0.152000	-1.49e-01	-2.35e-01	-0.409000	0.063100	-1.12e-01	1.96e-01	6.00e-01	2.91e-01	2.60e-01	1.51e-01	9.97e-03	8.93e-01	4.58e-01
REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	13	1.06e-01	2.63e-01	0.563	-0.134000	-0.06700	-0.241000	2.67e-01	-8.74e-02	-0.191000	-0.187000	2.95e-01	3.10e-01	6.51e-01	1.07e-01	7.64e-02	4.93e-01	1.95e-01	2.27e-01	5.49e-02
REACTOME HS GAG DEGRADATION	11	7.24e-02	2.05e-01	0.563	-0.212000	0.01430	-0.037100	3.75e-01	6.82e-02	0.004740	-0.259000	2.41e-01	2.24e-01	8.08e-01	8.98e-01	2.93e-02	7.02e-01	9.90e-01	1.32e-01	1.71e-01
REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	43	3.37e-07	3.69e-06	0.563	0.188000	0.25200	0.049600	-4.96e-02	7.01e-02	0.435000	0.129000	-4.88e-02	3.14e-02	3.21e-03	5.76e-01	5.89e-01	4.09e-01	4.55e-07	9.12e-02	6.99e-01
REACTOME PEROXISOMAL LIPID METABOLISM	16	9.17e-02	2.40e-01	0.563	-0.121000	-0.23800	-0.094100	-2.12e-01	3.52e-01	0.222000	-0.085400	1.07e-01	3.02e-01	8.12e-02	4.71e-01	1.29e-01	1.85e-02	1.18e-01	5.37e-01	4.52e-01
REACTOME PEPTIDE LIGAND BINDING RECEPTORS	14	2.88e-01	4.64e-01	0.562	-0.039200	-0.15500	-0.288000	4.55e-02	-4.46e-02	-0.369000	-0.188000	1.77e-01	4.26e-01	4.02e-01	9.03e-02	2.88e-01	6.70e-01	1.10e-01	2.54e-01	2.00e-01
REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	43	2.05e-07	2.54e-06	0.561	0.230000	0.22800	0.052500	-7.11e-02	9.85e-02	0.415000	0.133000	-5.09e-02	8.24e-03	7.61e-03	5.53e-01	4.28e-01	2.46e-01	1.52e-06	8.20e-02	6.80e-01
REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	41	2.74e-07	3.14e-06	0.561	0.187000	0.22200	0.009680	-2.24e-02	8.90e-02	0.456000	0.104000	-5.71e-02	3.50e-02	1.12e-02	9.38e-01	8.30e-01	3.01e-01	2.46e-07	1.69e-01	6.43e-01
REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	43	1.64e-07	2.09e-06	0.560	0.198000	0.24200	0.039800	-5.12e-02	7.10e-02	0.436000	0.109000	-7.22e-02	2.33e-02	4.70e-03	6.59e-01	5.76e-01	4.03e-01	4.22e-07	1.47e-01	5.02e-01
REACTOME LIPOPROTEIN METABOLISM	12	4.38e-01	5.98e-01	0.560	-0.252000	0.15100	-0.165000	2.71e-01	-2.30e-01	0.052500	-0.220000	-1.49e-01	2.05e-01	3.68e-01	3.06e-01	9.75e-02	1.41e-01	7.83e-01	1.91e-01	3.50e-01
REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	13	9.70e-02	2.47e-01	0.560	0.109000	0.02620	0.337000	2.82e-01	-1.50e-01	-0.291000	0.004670	3.61e-02	6.01e-01	8.73e-01	2.99e-02	6.12e-02	2.77e-01	5.10e-02	9.82e-01	8.36e-01
REACTOME VOLTAGE GATED POTASSIUM CHANNELS	11	3.61e-01	5.39e-01	0.560	0.322000	-0.05470	0.143000	-9.73e-02	-1.68e-03	-0.392000	-0.150000	1.50e-02	3.63e-02	7.44e-01	4.28e-01	3.91e-01	7.23e-01	2.16e-02	4.81e-01	6.66e-01
REACTOME TCR SIGNALING	30	2.83e-02	9.89e-02	0.560	-0.442000	-0.11800	-0.142000	-2.24e-02	-2.27e-01	0.013900	-0.151000	-9.28e-02	4.86e-04	2.22e-01	2.19e-01	7.78e-01	1.84e-01	7.89e-01	2.02e-01	6.44e-01
REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	13	1.63e-01	3.39e-01	0.557	-0.066200	0.14700	0.074200	9.46e-02	-3.16e-01	-0.119000	0.331000	-2.15e-01	5.58e-01	3.41e-01	6.51e-01	5.19e-01	3.15e-02	4.10e-01	3.37e-02	1.46e-01
REACTOME POTASSIUM CHANNELS	22	3.57e-02	1.18e-01	0.554	0.262000	-0.14400	0.088800	-1.41e-01	6.92e-02	-0.400000	-0.134000	-8.60e-02	2.91e-02	2.24e-01	4.86e-01	1.68e-01	4.49e-01	6.85e-04	3.20e-01	2.53e-01
REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY	11	5.92e-01	7.24e-01	0.552	-0.294000	0.22400	-0.094300	3.37e-02	-1.28e-01	0.292000	0.238000	-2.37e-02	1.18e-01	2.84e-01	5.75e-01	9.83e-01	5.93e-01	9.91e-02	1.30e-01	7.58e-01
REACTOME TELOMERE MAINTENANCE	20	6.97e-02	1.99e-01	0.551	-0.287000	0.13100	0.077000	-9.66e-02	-3.07e-01	0.077900	0.226000	-1.94e-01	4.91e-02	3.64e-01	4.93e-01	4.07e-01	6.81e-03	5.75e-01	9.54e-02	1.33e-01
REACTOME PURINE SALVAGE	10	4.22e-01	5.87e-01	0.544	-0.092500	0.11600	0.139000	-2.75e-01	-2.66e-01	-0.080500	-0.200000	-2.48e-01	6.49e-01	2.08e-01	5.51e-01	1.63e-01	3.38e-01	6.16e-01	3.51e-01	2.26e-01
REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS	25	4.64e-02	1.46e-01	0.542	0.262000	-0.12400	0.010600	-6.26e-02	7.62e-02	-0.310000	-0.022900	3.21e-01	2.41e-02	2.55e-01	7.60e-01	6.11e-01	5.70e-01	1.10e-02	8.60e-01	8.17e-03
REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT	23	4.73e-02	1.47e-01	0.540	-0.323000	-0.08600	-0.320000	6.56e-02	-1.65e-01	-0.098900	-0.120000	-1.49e-01	2.03e-02	2.69e-01	1.38e-02	5.64e-01	2.27e-01	3.03e-01	3.47e-01	2.89e-01
REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	11	2.84e-01	4.62e-01	0.540	-0.080100	-0.07190	-0.229000	1.23e-01	3.76e-03	0.064300	-0.016400	4.56e-01	5.35e-01	6.56e-01	1.59e-01	4.46e-01	9.25e-01	7.29e-01	9.17e-01	6.02e-03
REACTOME INTEGRIN CELL SURFACE INTERACTIONS	46	1.77e-04	1.21e-03	0.537	-0.074300	-0.06150	-0.247000	2.08e-01	-1.99e-01	-0.245000	-0.254000	1.03e-01	8.47e-01	5.55e-01	3.45e-03	1.23e-02	5.66e-02	4.17e-03	6.42e-03	8.48e-02
REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX	46	2.54e-07	2.99e-06	0.536	0.186000	0.23800	0.018000	-2.21e-02	5.89e-02	0.425000	0.083800	-6.96e-02	3.32e-02	4.07e-03	8.02e-01	8.25e-01	5.91e-01	5.86e-07	1.55e-01	5.05e-01
REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	16	1.52e-01	3.28e-01	0.536	0.109000	0.02330	0.268000	2.50e-01	-1.94e-01	-0.316000	0.030500	4.44e-02	6.10e-01	8.84e-01	5.11e-02	1.55e-01	1.56e-01	3.46e-02	9.27e-01	9.77e-01
REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	15	2.26e-01	4.17e-01	0.536	0.017600	0.28400	0.161000	-5.29e-02	4.89e-02	0.271000	0.208000	-2.41e-01	9.52e-01	4.66e-02	2.72e-01	7.29e-01	8.41e-01	6.28e-02	1.53e-01	8.04e-02
REACTOME DOUBLE STRAND BREAK REPAIR	13	3.76e-01	5.50e-01	0.535	-0.056900	0.22200	0.289000	1.84e-01	5.60e-02	0.304000	0.133000	5.66e-02	9.21e-01	1.65e-01	7.40e-02	2.38e-01	5.44e-01	6.13e-02	4.15e-01	7.42e-01
REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM	25	1.29e-02	5.14e-02	0.533	-0.106000	-0.14100	-0.196000	2.79e-01	-1.06e-02	-0.182000	-0.286000	1.46e-01	3.70e-01	2.38e-01	1.88e-01	1.36e-02	8.91e-01	1.62e-01	2.56e-02	9.88e-02
REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	18	4.79e-02	1.48e-01	0.533	-0.338000	-0.15000	-0.082500	2.17e-01	-2.51e-01	-0.021200	-0.152000	8.18e-02	6.60e-03	2.41e-01	5.00e-01	8.95e-02	4.17e-02	8.29e-01	2.48e-01	5.49e-01
REACTOME SIGNALING BY ROBO RECEPTOR	20	1.25e-01	2.90e-01	0.532	-0.127000	0.08990	0.028900	1.78e-01	-3.42e-01	-0.268000	-0.073500	-1.79e-01	3.89e-01	4.85e-01	8.57e-01	1.49e-01	7.29e-03	3.98e-02	4.19e-01	1.41e-01
REACTOME METAL ION SLC TRANSPORTERS	12	2.77e-01	4.59e-01	0.529	-0.006570	-0.25300	-0.132000	-1.82e-01	1.36e-02	-0.207000	0.004930	3.50e-01	8.41e-01	1.07e-01	3.89e-01	2.61e-01	9.70e-01	1.78e-01	9.81e-01	2.83e-02
REACTOME BASE EXCISION REPAIR	13	5.97e-01	7.28e-01	0.527	-0.302000	0.15200	0.020100	6.31e-02	-1.15e-01	0.290000	0.232000	-9.09e-02	6.98e-02	4.59e-01	8.92e-01	8.00e-01	5.80e-01	7.35e-02	1.14e-01	8.42e-01
REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	17	1.31e-01	3.02e-01	0.527	0.095500	0.33000	0.122000	-9.78e-03	-1.06e-01	0.128000	0.215000	-2.66e-01	6.16e-01	1.37e-02	3.80e-01	9.63e-01	3.56e-01	3.64e-01	1.16e-01	4.07e-02
REACTOME AQUAPORIN MEDIATED TRANSPORT	22	1.64e-02	6.22e-02	0.526	-0.172000	-0.23300	0.128000	-3.80e-01	4.29e-02	-0.161000	0.006570	-6.82e-02	3.07e-01	2.60e-02	3.17e-01	2.95e-03	6.04e-01	1.12e-01	7.03e-01	7.35e-01
REACTOME MYOGENESIS	22	1.60e-02	6.18e-02	0.526	0.106000	-0.04330	-0.023200	3.05e-01	-2.35e-01	-0.166000	-0.244000	-1.68e-01	3.86e-01	7.06e-01	8.14e-01	2.01e-02	3.83e-02	1.50e-01	4.49e-02	1.47e-01
REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	44	1.11e-06	1.14e-05	0.524	0.226000	0.24100	0.010800	-1.23e-02	7.42e-02	0.385000	0.105000	-2.04e-02	8.71e-03	4.39e-03	9.26e-01	9.18e-01	3.80e-01	6.41e-06	1.54e-01	9.62e-01
REACTOME GLYCOLYSIS	19	1.09e-01	2.68e-01	0.522	0.143000	0.23200	0.240000	7.97e-02	1.59e-01	0.267000	0.098600	-1.66e-01	3.70e-01	6.80e-02	6.35e-02	5.09e-01	2.81e-01	3.90e-02	4.49e-01	1.72e-01
REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C	54	1.56e-07	2.04e-06	0.521	0.160000	0.24800	0.038200	-4.72e-02	4.99e-02	0.379000	0.137000	-1.24e-01	4.76e-02	1.14e-03	6.41e-01	5.66e-01	5.46e-01	8.55e-07	5.02e-02	1.31e-01
REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING	11	1.47e-01	3.24e-01	0.518	-0.134000	-0.24400	0.032200	-3.27e-01	3.36e-02	-0.250000	0.035500	-1.33e-01	3.90e-01	1.57e-01	6.96e-01	6.27e-02	9.38e-01	6.59e-02	8.46e-01	2.30e-01
REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	15	2.28e-01	4.19e-01	0.518	0.053100	0.26300	0.154000	-2.15e-02	-6.82e-02	0.165000	0.193000	-3.20e-01	8.55e-01	6.52e-02	2.95e-01	9.00e-01	5.45e-01	2.65e-01	1.86e-01	2.08e-02
REACTOME INWARDLY RECTIFYING K CHANNELS	10	4.82e-01	6.39e-01	0.516	0.127000	-0.16300	-0.040100	-2.10e-01	9.67e-02	-0.375000	-0.094300	-1.42e-01	5.77e-01	3.44e-01	7.96e-01	2.37e-01	6.66e-01	2.81e-02	5.91e-01	3.94e-01
REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	21	1.64e-02	6.22e-02	0.516	-0.146000	-0.22600	0.128000	-3.80e-01	3.69e-02	-0.164000	-0.016600	-6.82e-02	3.07e-01	2.60e-02	3.17e-01	2.95e-03	6.04e-01	1.12e-01	7.03e-01	7.35e-01
REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	57	7.56e-08	1.11e-06	0.516	0.166000	0.24200	0.068500	-4.87e-02	3.86e-02	0.366000	0.144000	-1.29e-01	3.53e-02	1.07e-03	3.71e-01	5.42e-01	6.48e-01	1.06e-06	3.68e-02	1.03e-01
REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	18	6.96e-02	1.99e-01	0.515	0.327000	-0.20100	0.117000	3.70e-02	2.09e-01	0.015100	-0.180000	1.63e-01	2.48e-02	1.18e-01	3.88e-01	7.54e-01	1.55e-01	9.49e-01	1.70e-01	2.19e-01
REACTOME REGULATION OF MITOTIC CELL CYCLE	61	1.85e-08	3.20e-07	0.513	0.169000	0.23300	0.055400	-6.21e-02	4.92e-02	0.368000	0.155000	-1.05e-01	2.76e-02	1.16e-03	4.60e-01	4.12e-01	5.46e-01	3.78e-07	2.09e-02	1.74e-01
REACTOME SOS MEDIATED SIGNALLING	13	2.18e-01	4.09e-01	0.512	-0.021100	0.16500	-0.077100	5.17e-02	-3.58e-01	-0.102000	0.146000	-2.58e-01	7.64e-01	2.84e-01	5.90e-01	7.17e-01	1.56e-02	4.76e-01	3.51e-01	8.24e-02
REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	47	2.24e-06	2.07e-05	0.512	0.213000	0.25200	0.054300	-8.19e-03	6.50e-02	0.370000	0.090700	-2.66e-02	1.15e-02	2.04e-03	5.22e-01	9.56e-01	4.36e-01	7.54e-06	2.01e-01	8.85e-01
REACTOME HS GAG BIOSYNTHESIS	15	2.60e-01	4.44e-01	0.511	0.047700	-0.08160	0.053600	2.35e-01	-1.38e-01	-0.286000	-0.305000	-1.78e-02	7.27e-01	5.99e-01	4.44e-01	1.05e-01	5.12e-01	8.42e-02	8.43e-02	7.74e-01
REACTOME CELL CELL JUNCTION ORGANIZATION	15	2.51e-01	4.35e-01	0.511	-0.064100	-0.02540	-0.051500	1.84e-01	-2.62e-01	-0.178000	-0.204000	-2.78e-01	7.75e-01	9.15e-01	4.69e-01	1.87e-01	7.79e-02	1.41e-01	2.53e-01	7.34e-02
REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	57	6.04e-08	9.48e-07	0.507	0.170000	0.22900	0.046000	-5.96e-02	4.48e-02	0.370000	0.117000	-1.30e-01	3.16e-02	1.99e-03	5.59e-01	4.48e-01	5.90e-01	7.83e-07	8.32e-02	9.82e-02
REACTOME PHASE II CONJUGATION	24	2.97e-02	1.02e-01	0.506	0.271000	-0.20800	0.148000	-1.02e-01	2.34e-01	0.051500	0.157000	1.58e-01	1.26e-02	3.35e-02	2.12e-01	3.93e-01	3.53e-02	9.39e-01	2.57e-01	2.27e-01
REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	11	9.83e-02	2.47e-01	0.505	-0.115000	0.23600	-0.263000	1.38e-01	1.27e-02	0.062600	0.274000	-1.39e-01	4.09e-01	1.57e-01	1.07e-01	3.95e-01	9.67e-01	7.37e-01	1.07e-01	3.80e-01
REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	22	2.19e-02	7.88e-02	0.505	-0.195000	-0.14000	-0.193000	2.87e-01	-2.53e-02	-0.108000	-0.038600	2.52e-01	1.22e-01	2.61e-01	5.79e-02	1.18e-02	6.56e-01	3.63e-01	4.77e-01	3.12e-02
REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	16	2.11e-01	4.03e-01	0.504	0.074200	0.31900	0.087200	-6.57e-03	-6.43e-02	0.176000	0.182000	-2.65e-01	7.37e-01	2.08e-02	5.51e-01	9.83e-01	5.51e-01	2.20e-01	1.97e-01	4.74e-02
REACTOME PHOSPHORYLATION OF THE APC C	14	2.91e-01	4.67e-01	0.503	0.025600	0.24600	0.116000	-1.87e-02	-1.73e-02	0.222000	0.154000	-3.24e-01	9.96e-01	9.62e-02	4.51e-01	9.19e-01	8.05e-01	1.43e-01	3.09e-01	2.40e-02
REACTOME MTORC1 MEDIATED SIGNALLING	11	5.33e-01	6.82e-01	0.500	0.209000	0.12900	0.079700	-8.94e-02	1.65e-01	0.270000	0.263000	8.09e-02	2.87e-01	4.42e-01	6.53e-01	6.05e-01	3.94e-01	1.13e-01	1.21e-01	6.44e-01
REACTOME EFFECTS OF PIP2 HYDROLYSIS	15	1.38e-01	3.11e-01	0.500	-0.412000	-0.04630	0.157000	1.18e-01	-8.96e-02	-0.123000	0.122000	4.67e-02	3.53e-02	8.88e-01	5.63e-01	4.39e-01	8.80e-01	4.20e-01	4.59e-01	4.86e-01
REACTOME DNA STRAND ELONGATION	14	3.95e-01	5.67e-01	0.500	-0.212000	0.18400	-0.011000	-3.26e-02	-2.28e-01	0.080700	0.329000	5.42e-02	2.82e-01	5.34e-01	9.20e-01	7.08e-01	1.96e-01	9.11e-01	2.22e-02	6.92e-01
REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	21	1.43e-01	3.17e-01	0.500	-0.193000	0.06610	-0.111000	-1.16e-02	-3.71e-01	-0.236000	0.038900	2.73e-02	2.25e-01	6.30e-01	4.90e-01	9.32e-01	4.82e-03	6.53e-02	7.36e-01	9.76e-01
REACTOME ORC1 REMOVAL FROM CHROMATIN	50	1.37e-06	1.31e-05	0.500	0.161000	0.23300	0.007690	-2.83e-02	4.75e-02	0.388000	0.121000	-2.96e-02	5.17e-02	3.32e-03	9.56e-01	7.55e-01	5.70e-01	1.21e-06	9.10e-02	8.38e-01
REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	11	3.09e-01	4.89e-01	0.497	-0.098400	0.03630	-0.367000	-1.18e-01	-4.42e-02	-0.170000	-0.133000	1.98e-01	4.12e-01	8.43e-01	3.27e-02	5.10e-01	4.49e-01	3.08e-01	5.18e-01	2.62e-01
REACTOME METABOLISM OF PORPHYRINS	12	6.30e-01	7.48e-01	0.496	0.262000	-0.02110	0.267000	-2.81e-01	5.93e-02	-0.127000	0.078100	-2.65e-02	3.26e-01	8.90e-01	1.14e-01	9.49e-02	8.16e-01	7.16e-01	6.49e-01	8.49e-01
REACTOME SPRY REGULATION OF FGF SIGNALING	12	2.58e-01	4.44e-01	0.494	-0.076600	-0.07900	-0.388000	2.45e-02	-1.50e-01	-0.240000	0.000858	2.22e-02	5.31e-01	6.10e-01	1.34e-02	8.59e-01	2.95e-01	1.20e-01	9.99e-01	9.12e-01
REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	16	9.67e-02	2.47e-01	0.494	-0.163000	-0.16500	0.177000	-3.39e-01	5.02e-03	-0.171000	0.088600	-8.05e-02	3.62e-01	1.14e-01	2.28e-01	2.49e-02	7.44e-01	1.38e-01	7.08e-01	7.55e-01
REACTOME NEGATIVE REGULATION OF FGFR SIGNALING	18	6.85e-02	1.98e-01	0.493	-0.069000	-0.12400	-0.278000	6.61e-02	-1.54e-01	-0.328000	-0.048200	8.97e-02	3.27e-01	4.42e-01	9.57e-03	8.37e-01	1.53e-01	3.18e-02	9.68e-01	3.44e-01
REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	19	2.15e-01	4.05e-01	0.493	0.013800	0.28600	0.246000	-8.89e-02	-1.37e-02	0.186000	0.219000	-9.83e-02	9.24e-01	2.42e-02	5.64e-02	5.00e-01	7.96e-01	1.55e-01	9.04e-02	4.09e-01
REACTOME VIRAL MESSENGER RNA SYNTHESIS	14	2.36e-01	4.21e-01	0.492	-0.226000	0.04520	0.131000	-2.41e-01	-8.87e-02	0.257000	0.129000	-1.50e-01	9.72e-02	7.68e-01	3.93e-01	1.07e-01	4.71e-01	8.81e-02	3.92e-01	2.87e-01
REACTOME ER PHAGOSOME PATHWAY	50	3.67e-06	3.26e-05	0.491	0.041000	0.19400	-0.022400	-4.47e-02	6.66e-03	0.416000	0.147000	-6.93e-02	5.19e-01	1.53e-02	7.41e-01	6.06e-01	8.90e-01	2.61e-07	4.54e-02	4.77e-01
REACTOME SHC MEDIATED SIGNALLING	13	1.86e-01	3.68e-01	0.488	-0.041400	0.09860	-0.035400	7.11e-02	-2.42e-01	-0.084600	0.326000	-2.20e-01	6.68e-01	5.25e-01	7.91e-01	6.24e-01	9.40e-02	5.49e-01	3.66e-02	1.36e-01
REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	46	2.83e-07	3.17e-06	0.487	0.235000	0.17900	0.010600	-1.05e-01	3.46e-02	0.356000	0.106000	-7.32e-04	5.59e-03	3.12e-02	9.27e-01	2.16e-01	6.85e-01	2.08e-05	1.47e-01	8.52e-01
REACTOME SHC1 EVENTS IN EGFR SIGNALING	14	3.10e-01	4.89e-01	0.487	-0.090600	0.09060	0.077300	8.05e-02	-2.90e-01	0.000515	0.208000	-2.85e-01	4.42e-01	5.46e-01	6.24e-01	5.67e-01	3.94e-02	9.66e-01	1.68e-01	4.69e-02
REACTOME G ALPHA I SIGNALLING EVENTS	31	8.12e-03	3.54e-02	0.486	-0.208000	-0.15800	-0.115000	-1.84e-01	-1.17e-01	-0.319000	0.007310	7.30e-02	1.25e-01	7.77e-02	3.40e-01	2.03e-01	5.00e-01	3.00e-03	9.26e-01	2.51e-01
REACTOME ASSEMBLY OF THE PRE REPLICATIVE COMPLEX	49	2.09e-06	1.97e-05	0.485	0.144000	0.20800	-0.008120	-5.18e-02	3.11e-02	0.394000	0.094400	-5.91e-02	9.72e-02	9.61e-03	9.32e-01	5.49e-01	8.42e-01	1.88e-06	1.16e-01	5.69e-01
REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	21	2.81e-02	9.87e-02	0.482	0.285000	0.08070	0.171000	2.84e-02	-2.01e-01	-0.248000	0.026700	1.09e-01	1.60e-02	7.03e-01	1.77e-01	9.50e-01	1.37e-01	3.80e-02	9.04e-01	3.94e-01
REACTOME SIGNALLING TO P38 VIA RIT AND RIN	11	4.92e-01	6.48e-01	0.482	0.009260	0.12800	0.061700	1.55e-01	-2.53e-01	-0.127000	0.133000	-3.00e-01	9.21e-01	4.48e-01	7.33e-01	3.37e-01	1.08e-01	4.20e-01	4.37e-01	6.37e-02
REACTOME ACTIVATION OF BH3 ONLY PROTEINS	11	5.64e-01	7.04e-01	0.479	-0.049800	0.08270	-0.246000	-1.41e-01	-2.06e-01	-0.166000	-0.086500	-2.50e-01	6.10e-01	4.07e-01	2.67e-01	4.29e-01	1.81e-01	5.24e-01	9.76e-01	2.10e-01
REACTOME ION CHANNEL TRANSPORT	18	1.35e-01	3.07e-01	0.478	-0.052400	-0.27000	-0.280000	-6.60e-02	7.96e-03	0.014200	-0.162000	2.07e-01	5.57e-01	3.56e-02	2.79e-02	6.31e-01	9.29e-01	9.55e-01	2.16e-01	1.16e-01
REACTOME SEMAPHORIN INTERACTIONS	43	2.34e-03	1.20e-02	0.476	-0.131000	0.06560	-0.066300	8.92e-02	-3.08e-01	-0.242000	-0.198000	-2.05e-02	1.91e-01	4.61e-01	4.07e-01	2.81e-01	7.65e-04	3.82e-03	3.91e-02	9.28e-01
REACTOME FATTY ACYL COA BIOSYNTHESIS	12	4.36e-02	1.41e-01	0.476	-0.000807	0.07470	-0.203000	2.18e-01	-2.48e-01	0.162000	-0.103000	-1.85e-01	6.18e-01	4.74e-01	2.02e-01	2.03e-01	3.25e-01	6.76e-02	3.90e-01	2.71e-01
REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	14	3.66e-01	5.41e-01	0.476	-0.003870	0.14400	0.121000	6.80e-02	-3.07e-01	-0.097500	0.233000	-1.69e-01	8.43e-01	3.33e-01	4.33e-01	6.26e-01	3.02e-02	4.77e-01	1.22e-01	2.32e-01
REACTOME REGULATION OF APOPTOSIS	49	1.83e-05	1.39e-04	0.473	0.164000	0.22400	0.051500	-7.39e-03	3.15e-02	0.349000	0.145000	7.41e-03	4.93e-02	5.12e-03	5.37e-01	9.63e-01	7.15e-01	1.67e-05	4.82e-02	7.78e-01
REACTOME SIGNALING BY NODAL	11	1.54e-01	3.28e-01	0.471	0.143000	-0.28200	0.057200	2.94e-01	-8.05e-02	-0.144000	0.037000	-6.21e-02	4.96e-01	8.67e-02	7.53e-01	7.31e-02	5.55e-01	3.64e-01	8.32e-01	6.84e-01
REACTOME CTLA4 INHIBITORY SIGNALING	16	2.50e-01	4.35e-01	0.471	-0.145000	-0.14200	-0.308000	-9.72e-02	-1.23e-01	-0.114000	-0.178000	-1.27e-01	4.03e-01	1.74e-01	2.75e-02	5.10e-01	5.44e-01	2.52e-01	1.17e-01	3.50e-01
REACTOME MRNA SPLICING	100	3.69e-10	8.27e-09	0.467	-0.243000	0.04400	0.045600	-4.20e-02	1.45e-02	0.192000	0.340000	2.77e-02	1.21e-06	4.54e-01	5.82e-01	3.91e-01	8.42e-01	7.36e-04	1.63e-09	7.49e-01
REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	10	7.07e-01	7.91e-01	0.466	-0.013800	-0.12800	0.260000	1.07e-01	-4.44e-02	0.077700	0.331000	5.75e-02	9.95e-01	5.02e-01	1.90e-01	4.51e-01	8.59e-01	7.15e-01	1.28e-01	7.85e-01
REACTOME PLATELET HOMEOSTASIS	36	1.50e-02	5.88e-02	0.465	-0.110000	-0.28600	0.042000	-2.04e-01	-2.37e-02	-0.210000	-0.074400	-1.69e-01	6.36e-01	3.05e-03	7.05e-01	2.08e-02	8.86e-01	2.56e-02	2.56e-01	7.13e-02
REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	10	4.84e-01	6.40e-01	0.464	-0.180000	-0.16200	-0.053900	6.95e-02	2.78e-01	-0.075300	-0.250000	6.17e-02	5.17e-01	3.72e-01	7.48e-01	6.90e-01	1.69e-01	6.54e-01	1.78e-01	7.54e-01
REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	16	8.47e-02	2.28e-01	0.461	-0.318000	-0.06170	-0.122000	-1.87e-01	-1.22e-02	-0.072500	0.209000	9.28e-02	1.35e-02	8.06e-01	3.05e-01	3.32e-01	7.71e-01	7.38e-01	2.02e-01	5.32e-01
REACTOME TIE2 SIGNALING	13	5.28e-01	6.82e-01	0.460	-0.046400	-0.19000	-0.249000	-1.64e-01	1.77e-01	0.080800	-0.216000	1.08e-02	6.45e-01	2.07e-01	9.67e-02	2.94e-01	3.16e-01	6.27e-01	1.62e-01	9.69e-01
REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	15	3.01e-01	4.80e-01	0.460	-0.082600	-0.28600	-0.060400	-2.06e-01	1.65e-01	0.142000	-0.050000	1.64e-01	4.59e-01	4.22e-02	6.45e-01	1.55e-01	3.17e-01	3.42e-01	7.24e-01	2.59e-01
REACTOME MUSCLE CONTRACTION	36	8.67e-03	3.71e-02	0.459	0.184000	-0.25700	0.118000	-1.73e-01	1.62e-01	0.000401	0.045000	1.96e-01	9.76e-02	4.76e-03	2.19e-01	6.55e-02	1.30e-01	9.44e-01	6.39e-01	3.54e-02
REACTOME SMOOTH MUSCLE CONTRACTION	18	1.04e-01	2.58e-01	0.458	-0.077800	-0.29000	0.209000	-1.05e-01	-3.76e-02	-0.216000	0.107000	7.17e-02	4.38e-01	2.40e-02	1.16e-01	4.37e-01	6.66e-01	8.49e-02	4.24e-01	6.03e-01
REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	21	6.41e-03	2.96e-02	0.455	-0.156000	0.12300	-0.075400	-9.83e-02	-1.83e-01	-0.311000	0.133000	-6.46e-02	2.34e-01	2.54e-01	3.08e-01	3.69e-01	2.09e-01	1.45e-02	4.80e-01	6.61e-01
REACTOME M G1 TRANSITION	52	1.30e-05	1.04e-04	0.451	0.140000	0.20500	0.001500	-4.94e-02	2.45e-02	0.356000	0.097900	-5.11e-02	9.92e-02	8.56e-03	9.72e-01	5.58e-01	9.08e-01	9.65e-06	1.01e-01	6.20e-01
REACTOME MRNA SPLICING MINOR PATHWAY	39	3.58e-03	1.78e-02	0.451	-0.259000	0.07500	0.114000	-7.84e-02	-1.16e-01	0.078300	0.299000	-4.88e-02	1.62e-03	4.66e-01	2.78e-01	4.03e-01	1.31e-01	4.16e-01	7.23e-04	5.44e-01
REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	58	2.65e-06	2.40e-05	0.451	0.023400	0.16800	-0.096700	-2.01e-02	1.16e-02	0.382000	0.121000	-6.32e-02	6.99e-01	2.41e-02	1.66e-01	8.24e-01	8.64e-01	3.32e-07	7.53e-02	4.72e-01
REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	17	2.19e-01	4.09e-01	0.450	-0.003470	-0.20200	0.147000	8.48e-02	1.67e-01	-0.193000	-0.254000	-5.58e-02	8.45e-01	1.37e-01	3.01e-01	5.20e-01	2.97e-01	1.46e-01	6.89e-02	6.56e-01
REACTOME NRAGE SIGNALS DEATH THROUGH JNK	29	9.43e-02	2.45e-01	0.449	0.056400	-0.20200	-0.021100	8.99e-02	-7.68e-02	-0.290000	-0.229000	8.20e-02	4.47e-01	7.75e-02	8.72e-01	3.86e-01	3.74e-01	9.96e-03	6.42e-02	3.27e-01
REACTOME DESTABILIZATION OF MRNA BY KSRP	14	2.25e-01	4.17e-01	0.449	-0.210000	-0.07360	0.093500	-1.82e-01	-3.29e-01	-0.043400	-0.001770	1.75e-03	5.10e-02	6.20e-01	8.71e-01	4.09e-01	2.81e-02	7.65e-01	6.52e-01	9.50e-01
REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH	34	3.19e-02	1.08e-01	0.449	-0.088700	0.17800	-0.063800	3.16e-01	-2.09e-01	0.025500	0.055700	1.01e-01	2.39e-01	6.18e-02	4.67e-01	7.04e-04	1.79e-02	8.43e-01	5.71e-01	3.06e-01
REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	54	6.70e-06	5.74e-05	0.448	0.126000	0.16400	-0.039300	-6.42e-02	4.24e-02	0.339000	0.188000	-2.92e-03	1.24e-01	3.18e-02	5.65e-01	4.24e-01	6.14e-01	1.12e-05	8.45e-03	8.96e-01
REACTOME SYNTHESIS OF PA	12	5.81e-01	7.17e-01	0.447	0.194000	-0.19000	0.154000	-2.72e-01	6.22e-02	-0.140000	0.048100	-4.41e-02	1.25e-01	2.68e-01	3.92e-01	1.22e-01	8.12e-01	3.99e-01	9.05e-01	7.76e-01
REACTOME GLYCOSAMINOGLYCAN METABOLISM	52	1.14e-03	6.40e-03	0.443	-0.128000	-0.13200	-0.072300	3.17e-01	-8.35e-02	-0.138000	-0.127000	1.22e-01	1.23e-01	2.19e-01	4.97e-01	2.01e-04	5.36e-01	2.37e-01	6.57e-02	1.27e-01
REACTOME SEMA4D IN SEMAPHORIN SIGNALING	23	2.79e-01	4.60e-01	0.442	-0.164000	0.05490	-0.001690	1.28e-01	-3.60e-01	-0.109000	-0.067000	6.28e-02	3.66e-01	6.66e-01	9.55e-01	2.74e-01	8.47e-03	3.36e-01	8.29e-01	4.18e-01
REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	19	1.22e-01	2.86e-01	0.442	-0.230000	-0.08060	0.101000	-1.86e-01	-5.09e-02	0.243000	0.089200	-1.44e-01	4.96e-02	5.13e-01	4.48e-01	1.49e-01	5.84e-01	6.06e-02	4.94e-01	2.32e-01
REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	21	2.78e-01	4.59e-01	0.441	0.047900	0.07590	-0.027700	1.36e-01	-2.94e-01	-0.268000	-0.031200	-8.70e-02	8.71e-01	5.47e-01	9.08e-01	2.56e-01	1.28e-02	4.53e-02	9.89e-01	4.51e-01
REACTOME MHC CLASS II ANTIGEN PRESENTATION	62	4.59e-04	2.95e-03	0.439	-0.224000	0.17500	0.038600	1.99e-01	-3.90e-02	0.258000	-0.027800	-4.89e-02	1.50e-03	1.05e-02	5.62e-01	4.69e-03	5.68e-01	2.65e-04	7.77e-01	4.49e-01
REACTOME GLYCOSPHINGOLIPID METABOLISM	23	1.18e-01	2.79e-01	0.439	-0.290000	-0.15000	0.031100	1.43e-01	-1.56e-01	0.010800	-0.021100	-1.98e-01	1.13e-02	2.29e-01	7.50e-01	2.46e-01	1.58e-01	6.42e-01	7.59e-01	8.62e-02
REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	23	6.45e-02	1.89e-01	0.438	-0.108000	0.25500	-0.051400	1.51e-01	-9.89e-02	-0.040300	-0.208000	-1.86e-01	5.24e-01	3.57e-02	7.09e-01	1.39e-01	5.93e-01	6.95e-01	1.11e-01	8.14e-02
REACTOME PROLONGED ERK ACTIVATION EVENTS	16	2.85e-01	4.62e-01	0.437	-0.059200	0.07810	-0.244000	2.09e-02	-2.47e-01	-0.224000	-0.083400	-5.31e-02	5.48e-01	5.79e-01	7.01e-02	8.58e-01	5.81e-02	9.24e-02	5.47e-01	6.71e-01
REACTOME ION TRANSPORT BY P TYPE ATPASES	17	1.89e-01	3.71e-01	0.437	-0.058800	-0.24600	-0.264000	-6.89e-02	-2.69e-02	0.045400	-0.118000	1.89e-01	5.37e-01	6.30e-02	4.41e-02	6.25e-01	7.33e-01	7.72e-01	3.81e-01	1.64e-01
REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	13	4.17e-01	5.83e-01	0.436	0.272000	0.12800	0.011900	-2.52e-01	1.24e-03	-0.097000	-0.146000	7.43e-02	1.20e-01	4.08e-01	9.64e-01	1.04e-01	9.06e-01	4.96e-01	3.43e-01	6.46e-01
REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	110	2.66e-09	5.45e-08	0.435	0.206000	0.05940	0.100000	-1.52e-01	2.09e-01	0.239000	0.093800	-3.39e-02	1.73e-04	2.13e-01	4.36e-02	8.38e-03	1.08e-04	7.60e-06	9.47e-02	7.99e-01
REACTOME DESTABILIZATION OF MRNA BY BRF1	16	1.79e-01	3.65e-01	0.435	-0.223000	-0.14100	0.029400	-1.40e-01	-2.92e-01	-0.087200	0.036300	7.33e-02	3.40e-02	3.13e-01	8.05e-01	5.35e-01	3.64e-02	5.13e-01	8.87e-01	6.30e-01
REACTOME REGULATION OF SIGNALING BY CBL	15	5.48e-01	6.92e-01	0.435	-0.195000	-0.07470	-0.292000	-6.30e-02	-2.32e-01	0.008310	-0.033900	-3.24e-02	4.89e-01	4.01e-01	5.17e-02	4.08e-01	3.64e-01	8.09e-01	7.77e-01	8.05e-01
REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	13	2.29e-01	4.19e-01	0.435	-0.141000	0.24100	-0.090300	-8.89e-02	-3.82e-02	0.220000	-0.008740	2.13e-01	4.96e-01	3.29e-02	4.48e-01	5.91e-01	4.86e-01	1.80e-01	9.51e-01	1.86e-01
REACTOME CTNNB1 PHOSPHORYLATION CASCADE	14	4.39e-01	5.98e-01	0.434	-0.009080	-0.15000	-0.125000	4.16e-02	-8.82e-02	-0.097400	-0.274000	-2.37e-01	8.16e-01	3.02e-01	3.77e-01	7.58e-01	4.73e-01	4.78e-01	6.60e-02	9.62e-02
REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	51	1.37e-05	1.08e-04	0.434	0.204000	0.17700	0.006590	-4.87e-03	5.40e-02	0.322000	0.092800	-9.52e-03	1.23e-02	2.46e-02	9.67e-01	9.88e-01	5.15e-01	5.15e-05	1.79e-01	9.57e-01
REACTOME BASIGIN INTERACTIONS	14	6.71e-01	7.64e-01	0.434	0.183000	0.07700	-0.143000	1.85e-02	1.89e-01	0.161000	0.149000	2.09e-01	5.02e-01	8.49e-01	3.33e-01	7.43e-01	2.63e-01	2.32e-01	3.42e-01	2.46e-01
REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	18	1.12e-01	2.72e-01	0.434	0.288000	-0.14600	0.044300	9.26e-02	-7.93e-02	-0.190000	0.023800	1.73e-01	5.08e-02	2.53e-01	7.62e-01	4.58e-01	4.56e-01	1.28e-01	8.64e-01	1.91e-01
REACTOME KERATAN SULFATE BIOSYNTHESIS	13	4.13e-01	5.81e-01	0.433	-0.039600	-0.02430	-0.104000	3.69e-01	4.08e-02	0.193000	-0.007980	5.78e-03	7.29e-01	8.74e-01	7.01e-01	2.48e-02	5.75e-01	2.62e-01	8.42e-01	9.95e-01
REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	24	5.53e-02	1.67e-01	0.433	0.278000	0.10400	0.087000	1.71e-02	-1.85e-01	-0.231000	-0.037500	4.61e-02	1.34e-02	5.09e-01	4.76e-01	9.01e-01	1.35e-01	3.80e-02	6.66e-01	7.16e-01
REACTOME SHC RELATED EVENTS	14	2.35e-01	4.21e-01	0.433	0.031600	0.07480	-0.012600	7.47e-02	-1.68e-01	-0.142000	0.322000	-1.53e-01	9.72e-01	6.19e-01	9.05e-01	5.94e-01	2.13e-01	3.11e-01	3.25e-02	2.80e-01
REACTOME GLUCOSE TRANSPORT	31	1.28e-02	5.14e-02	0.432	0.191000	0.23900	-0.049400	1.26e-01	8.86e-02	-0.020400	0.055300	2.53e-01	8.38e-02	4.04e-02	4.42e-01	1.62e-01	3.67e-01	6.85e-01	6.25e-01	6.12e-03
REACTOME SYNTHESIS OF DNA	62	4.64e-05	3.36e-04	0.431	0.093600	0.22800	0.020900	-1.35e-02	-8.81e-03	0.321000	0.147000	-1.36e-02	1.45e-01	3.36e-03	8.08e-01	8.26e-01	9.94e-01	2.34e-05	2.43e-02	9.85e-01
REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	16	1.35e-01	3.07e-01	0.431	-0.036500	-0.18700	0.235000	-1.59e-01	2.45e-02	-0.253000	0.031800	-5.34e-02	4.47e-01	1.31e-01	2.06e-01	1.39e-01	9.49e-01	3.63e-02	9.33e-01	9.82e-01
REACTOME KERATAN SULFATE KERATIN METABOLISM	16	2.69e-01	4.53e-01	0.431	-0.101000	-0.11000	-0.073000	3.82e-01	-6.38e-02	0.073800	0.036700	-2.41e-02	3.88e-01	4.47e-01	7.83e-01	8.64e-03	8.28e-01	6.49e-01	8.97e-01	8.43e-01
REACTOME COSTIMULATION BY THE CD28 FAMILY	37	1.50e-01	3.26e-01	0.429	-0.282000	-0.09290	-0.177000	-2.57e-02	-1.66e-01	0.059000	-0.138000	-1.19e-01	3.66e-02	2.22e-01	8.83e-02	7.46e-01	3.67e-01	6.95e-01	1.18e-01	2.73e-01
REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	18	3.13e-01	4.89e-01	0.428	-0.045400	0.14500	-0.190000	-1.35e-01	-1.75e-01	-0.152000	-0.107000	-2.01e-01	7.40e-01	1.75e-01	2.58e-01	3.38e-01	1.54e-01	3.87e-01	6.81e-01	1.89e-01
REACTOME NEPHRIN INTERACTIONS	15	7.39e-02	2.07e-01	0.427	-0.200000	-0.08500	-0.107000	-1.99e-01	7.24e-02	-0.204000	-0.076400	1.76e-01	2.55e-01	4.04e-01	4.48e-01	2.21e-01	4.10e-01	1.14e-01	6.15e-01	1.62e-01
REACTOME CELL CYCLE CHECKPOINTS	79	1.31e-06	1.31e-05	0.427	0.120000	0.24600	0.047800	1.69e-02	-3.60e-03	0.273000	0.143000	-9.80e-02	1.09e-01	1.98e-04	3.04e-01	7.57e-01	8.76e-01	6.23e-06	1.83e-02	1.43e-01
REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	29	9.14e-03	3.88e-02	0.422	0.269000	-0.06910	0.213000	1.77e-01	-2.45e-02	-0.061400	0.058100	1.30e-01	4.09e-02	4.94e-01	2.75e-02	8.17e-02	6.78e-01	7.00e-01	4.26e-01	2.24e-01
REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	44	3.32e-02	1.12e-01	0.421	-0.229000	0.11000	-0.006280	5.01e-02	-2.17e-01	0.080600	0.238000	9.60e-03	5.93e-03	2.11e-01	9.10e-01	5.09e-01	7.18e-03	4.83e-01	6.71e-03	9.55e-01
REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	16	1.91e-01	3.71e-01	0.421	-0.104000	-0.08980	0.091200	-1.76e-01	-2.71e-01	-0.118000	0.074400	1.62e-01	2.07e-01	5.18e-01	8.29e-01	3.71e-01	5.26e-02	3.77e-01	8.90e-01	2.49e-01
REACTOME REGULATION OF IFNA SIGNALING	10	8.62e-02	2.31e-01	0.418	-0.288000	0.05130	-0.000480	2.53e-01	-9.86e-02	-0.070900	-0.025700	9.73e-02	2.78e-02	2.49e-01	5.70e-01	2.67e-01	4.84e-01	3.39e-01	7.48e-01	7.04e-01
REACTOME METABOLISM OF MRNA	179	5.80e-17	1.71e-15	0.417	-0.145000	0.09950	-0.018400	-1.31e-01	-1.60e-01	0.149000	0.268000	-7.65e-02	7.73e-05	2.63e-02	5.26e-01	3.43e-03	2.17e-05	5.83e-04	2.18e-10	6.32e-02
REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES	27	1.41e-01	3.16e-01	0.416	0.214000	-0.13300	-0.221000	3.69e-02	-1.59e-02	-0.199000	-0.053800	1.30e-01	5.30e-02	2.28e-01	3.25e-02	7.41e-01	7.67e-01	1.01e-01	7.88e-01	2.16e-01
REACTOME NETRIN1 SIGNALING	23	1.83e-01	3.66e-01	0.415	-0.181000	-0.06590	-0.158000	-9.37e-05	-1.94e-01	-0.196000	-0.186000	-5.69e-03	1.11e-01	5.72e-01	1.75e-01	9.38e-01	3.87e-02	9.05e-02	1.41e-01	9.29e-01
REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	25	1.53e-01	3.28e-01	0.415	0.018800	0.26800	0.015300	2.28e-01	2.08e-02	0.146000	0.043800	1.56e-01	8.55e-01	4.21e-02	6.74e-01	5.00e-02	7.22e-01	2.75e-01	9.14e-01	6.36e-02
REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	16	6.35e-01	7.48e-01	0.415	-0.084500	0.19700	-0.013000	1.24e-01	-1.41e-01	0.133000	0.253000	-9.63e-02	3.14e-01	2.67e-01	8.89e-01	3.60e-01	2.69e-01	2.33e-01	8.24e-02	4.72e-01
REACTOME GLOBAL GENOMIC NER GG NER	25	2.84e-01	4.62e-01	0.415	-0.086500	0.20500	0.196000	2.15e-02	-1.06e-01	0.152000	0.219000	3.73e-02	3.80e-01	4.75e-02	1.32e-01	9.25e-01	3.22e-01	1.21e-01	5.51e-02	6.02e-01
REACTOME G ALPHA Z SIGNALLING EVENTS	21	2.07e-01	3.99e-01	0.414	-0.260000	-0.03560	0.190000	-2.22e-01	-2.44e-02	-0.107000	0.037800	-6.24e-02	1.40e-01	5.49e-01	4.06e-01	1.12e-01	6.44e-01	4.36e-01	6.78e-01	7.83e-01
REACTOME RNA POL I TRANSCRIPTION TERMINATION	19	3.39e-01	5.21e-01	0.414	-0.075000	0.16600	0.282000	-1.07e-01	-6.61e-02	0.136000	0.151000	-3.06e-02	4.38e-01	1.92e-01	2.82e-02	4.14e-01	5.07e-01	3.04e-01	2.43e-01	7.77e-01
REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	11	5.40e-01	6.85e-01	0.414	-0.004730	0.18100	-0.135000	1.41e-01	-2.61e-01	-0.155000	-0.090500	-7.78e-03	3.05e-01	3.37e-01	2.01e-01	6.56e-01	3.24e-01	2.98e-01	9.88e-01	4.14e-01
REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	23	1.59e-01	3.36e-01	0.414	-0.220000	-0.07870	0.010200	2.32e-01	-1.11e-01	-0.026400	-0.151000	1.63e-01	1.18e-01	5.02e-01	8.84e-01	4.96e-02	3.87e-01	7.82e-01	2.14e-01	1.82e-01
REACTOME INSULIN RECEPTOR RECYCLING	15	6.15e-01	7.43e-01	0.413	0.056300	-0.02580	-0.093000	-2.81e-02	2.25e-01	0.061400	0.167000	2.74e-01	8.39e-01	8.45e-01	4.90e-01	8.63e-01	1.58e-01	7.01e-01	2.51e-01	5.57e-02
REACTOME EGFR DOWNREGULATION	23	2.38e-01	4.21e-01	0.413	-0.173000	0.22100	-0.130000	2.14e-01	-1.59e-01	0.045900	-0.022500	3.21e-02	9.30e-02	5.61e-02	2.40e-01	5.78e-02	1.29e-01	7.34e-01	8.40e-01	8.10e-01
REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	16	3.48e-01	5.29e-01	0.412	-0.101000	-0.21500	-0.042500	-2.54e-01	1.77e-01	-0.038200	-0.039300	1.14e-01	4.29e-01	2.18e-01	9.67e-01	1.02e-01	1.28e-01	8.44e-01	6.23e-01	3.26e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	13	5.13e-01	6.68e-01	0.410	-0.117000	-0.21400	-0.044200	4.63e-02	-3.00e-02	-0.297000	0.102000	7.36e-02	5.41e-01	1.74e-01	7.57e-01	7.53e-01	7.60e-01	5.55e-02	5.35e-01	6.62e-01
REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	12	3.76e-01	5.50e-01	0.406	-0.002210	0.22400	-0.055600	-6.86e-04	-8.32e-02	-0.166000	-0.254000	-1.10e-01	8.62e-01	1.61e-01	7.03e-01	9.85e-01	5.26e-01	2.76e-01	1.15e-01	4.65e-01
REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	12	6.59e-01	7.63e-01	0.406	-0.031700	-0.09120	-0.248000	-7.21e-02	-1.11e-01	-0.009160	-0.267000	6.93e-02	8.85e-01	4.02e-01	1.28e-01	8.23e-01	7.38e-01	8.81e-01	9.44e-02	5.59e-01
REACTOME BIOLOGICAL OXIDATIONS	40	7.45e-02	2.07e-01	0.403	0.123000	-0.21100	0.076300	-1.57e-01	2.12e-01	0.015700	0.084700	1.42e-01	1.28e-01	1.46e-02	3.30e-01	9.53e-02	9.33e-03	9.54e-01	5.41e-01	1.19e-01
REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	19	4.41e-01	5.99e-01	0.402	-0.170000	-0.01120	-0.013800	1.41e-01	-2.83e-01	-0.106000	-0.045800	1.39e-01	2.63e-01	9.19e-01	8.85e-01	2.64e-01	4.54e-02	3.85e-01	7.23e-01	2.95e-01
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	127	1.84e-08	3.20e-07	0.401	-0.192000	0.07520	0.035600	6.87e-03	1.95e-02	0.180000	0.284000	6.02e-02	1.31e-05	1.92e-01	8.12e-01	9.82e-01	9.64e-01	5.02e-04	1.95e-08	2.15e-01
REACTOME IL RECEPTOR SHC SIGNALING	17	6.67e-01	7.63e-01	0.399	-0.174000	-0.05340	0.114000	-5.60e-02	4.33e-02	0.234000	0.231000	2.08e-02	4.98e-01	6.97e-01	4.42e-01	7.12e-01	5.34e-01	1.10e-01	1.13e-01	9.10e-01
REACTOME DOWNSTREAM TCR SIGNALING	20	1.89e-01	3.71e-01	0.399	-0.311000	-0.11200	-0.091700	-1.26e-01	-5.98e-02	0.123000	-0.084300	4.17e-03	8.08e-03	3.55e-01	4.32e-01	3.19e-01	5.28e-01	3.46e-01	4.96e-01	9.95e-01
REACTOME RNA POL III CHAIN ELONGATION	16	4.36e-01	5.97e-01	0.399	0.106000	0.17500	0.110000	-6.96e-02	-1.02e-01	0.125000	0.140000	-2.32e-01	5.74e-01	2.07e-01	4.44e-01	6.32e-01	3.87e-01	3.89e-01	3.21e-01	8.17e-02
REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	21	1.73e-01	3.57e-01	0.398	0.109000	0.08420	0.097400	-1.18e-01	-8.64e-02	0.004280	0.308000	-1.18e-01	5.08e-01	4.92e-01	4.42e-01	3.40e-01	3.88e-01	9.83e-01	1.22e-02	3.03e-01
REACTOME MICRORNA MIRNA BIOGENESIS	18	2.82e-01	4.61e-01	0.397	-0.129000	0.05200	0.216000	-1.29e-01	-1.62e-01	0.177000	0.117000	-6.00e-02	2.46e-01	6.99e-01	1.04e-01	3.33e-01	1.71e-01	1.90e-01	3.82e-01	6.13e-01
REACTOME INTERFERON ALPHA BETA SIGNALING	24	3.44e-01	5.27e-01	0.397	-0.280000	0.11100	0.008150	7.80e-02	-1.38e-01	-0.082500	-0.108000	-1.52e-01	3.33e-02	2.81e-01	5.62e-01	4.30e-01	7.03e-01	8.09e-01	6.56e-01	4.97e-01
REACTOME SIGNALING BY WNT	57	1.12e-05	9.06e-05	0.395	0.159000	0.14100	-0.022400	-2.20e-02	3.66e-02	0.313000	0.048700	-9.29e-02	4.45e-02	5.92e-02	7.20e-01	8.03e-01	6.68e-01	3.17e-05	4.22e-01	2.57e-01
REACTOME MEIOSIS	26	5.28e-01	6.82e-01	0.395	-0.257000	0.07000	-0.084200	9.91e-02	-1.22e-01	0.165000	0.162000	-5.65e-03	4.81e-02	5.88e-01	5.04e-01	3.60e-01	3.29e-01	1.59e-01	1.59e-01	9.25e-01
REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	24	7.85e-02	2.16e-01	0.394	0.063900	0.26000	-0.056300	1.75e-01	6.51e-02	0.066700	0.018400	2.02e-01	5.45e-01	5.62e-02	2.77e-01	1.46e-01	4.39e-01	7.37e-01	8.86e-01	2.36e-02
REACTOME P38MAPK EVENTS	10	8.81e-01	9.18e-01	0.393	0.102000	-0.14200	0.096800	-1.41e-01	-1.47e-02	-0.219000	-0.132000	-1.70e-01	6.75e-01	4.06e-01	5.98e-01	4.29e-01	8.46e-01	1.94e-01	4.53e-01	3.09e-01
REACTOME O LINKED GLYCOSYLATION OF MUCINS	13	4.62e-01	6.22e-01	0.392	-0.110000	0.05940	0.093200	1.52e-01	-1.61e-01	0.018100	-0.163000	-2.32e-01	9.45e-01	5.09e-01	3.67e-01	2.30e-01	4.63e-01	9.48e-01	7.79e-02	1.70e-01
REACTOME CHOLESTEROL BIOSYNTHESIS	13	1.86e-01	3.68e-01	0.391	-0.162000	0.11700	-0.219000	-1.69e-01	3.00e-02	-0.060900	0.011600	-1.78e-01	7.81e-02	3.69e-01	4.11e-01	5.11e-01	6.44e-01	5.52e-01	9.08e-01	1.99e-01
REACTOME MRNA 3 END PROCESSING	31	3.99e-02	1.30e-01	0.391	-0.167000	0.07720	0.032900	3.12e-02	7.53e-02	0.091900	0.251000	2.00e-01	3.54e-02	3.89e-01	8.91e-01	9.52e-01	7.19e-01	3.88e-01	1.49e-02	6.46e-02
REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	49	3.85e-03	1.89e-02	0.388	-0.093500	0.15400	0.022000	1.50e-01	9.04e-02	0.122000	0.199000	1.81e-01	1.79e-01	9.89e-02	8.89e-01	6.30e-02	2.53e-01	1.79e-01	1.95e-02	9.62e-03
REACTOME CHROMOSOME MAINTENANCE	38	5.65e-02	1.67e-01	0.387	-0.260000	-0.02670	0.032900	-1.88e-02	-1.36e-01	0.037100	0.188000	-1.59e-01	9.11e-03	4.82e-01	4.76e-01	8.38e-01	1.14e-01	5.70e-01	4.20e-02	9.95e-02
REACTOME G2 M CHECKPOINTS	17	7.44e-01	8.16e-01	0.385	-0.090800	0.20300	0.019000	1.22e-01	-1.11e-01	0.138000	0.211000	-8.81e-02	2.84e-01	2.25e-01	7.09e-01	3.56e-01	3.53e-01	2.11e-01	1.34e-01	4.95e-01
REACTOME MEIOTIC SYNAPSIS	17	6.34e-01	7.48e-01	0.384	-0.249000	-0.07180	-0.167000	6.46e-02	-1.17e-01	0.094800	0.159000	-1.50e-02	2.00e-01	5.03e-01	2.59e-01	6.31e-01	5.37e-01	5.35e-01	2.76e-01	8.88e-01
REACTOME PLATELET CALCIUM HOMEOSTASIS	10	5.91e-01	7.24e-01	0.384	0.030000	-0.25100	0.185000	3.09e-02	5.22e-02	0.019500	-0.044500	-2.07e-01	5.47e-01	1.67e-01	3.26e-01	8.50e-01	4.50e-01	9.45e-01	5.34e-01	2.42e-01
REACTOME FRS2 MEDIATED CASCADE	18	3.17e-01	4.92e-01	0.383	-0.078400	-0.01780	-0.000600	3.74e-02	-2.01e-01	-0.261000	0.132000	-1.12e-01	3.14e-01	9.48e-01	6.56e-01	9.72e-01	3.88e-02	1.27e-01	2.19e-01	5.52e-01
REACTOME DEADENYLATION OF MRNA	16	3.58e-01	5.38e-01	0.383	0.078400	-0.12200	0.198000	-7.30e-02	1.11e-01	0.195000	0.130000	-1.18e-01	7.14e-01	3.67e-01	1.62e-01	6.14e-01	5.16e-01	1.70e-01	3.60e-01	3.67e-01
REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION	15	4.10e-01	5.80e-01	0.383	-0.189000	0.00869	-0.193000	-1.66e-01	-1.28e-01	0.074100	0.086000	-1.27e-01	1.42e-01	9.62e-01	1.63e-01	2.52e-01	3.09e-01	6.36e-01	5.58e-01	3.48e-01
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION	116	1.68e-05	1.29e-04	0.381	-0.203000	-0.07220	-0.177000	-1.91e-03	-2.18e-01	-0.128000	-0.049300	2.89e-02	2.03e-03	1.23e-01	6.92e-04	8.00e-01	1.03e-03	1.02e-02	4.50e-01	4.38e-01
REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	25	2.34e-01	4.21e-01	0.379	-0.004990	0.14700	-0.036000	-9.31e-02	-1.15e-01	0.202000	0.187000	-1.51e-01	9.67e-01	2.62e-01	6.62e-01	4.26e-01	3.13e-01	1.33e-01	1.22e-01	2.63e-01
REACTOME GABA RECEPTOR ACTIVATION	15	1.73e-01	3.57e-01	0.377	-0.136000	-0.08630	-0.001440	-2.23e-01	4.01e-02	-0.243000	0.007930	7.43e-02	5.06e-01	3.29e-01	9.65e-01	1.90e-01	5.52e-01	4.79e-02	8.18e-01	3.91e-01
REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	12	7.85e-01	8.40e-01	0.376	0.109000	0.25400	-0.097600	-5.06e-02	-4.04e-02	-0.117000	0.130000	1.45e-01	5.72e-01	2.19e-01	8.22e-01	9.72e-01	5.23e-01	9.75e-01	3.46e-01	2.55e-01
REACTOME G ALPHA S SIGNALLING EVENTS	30	9.60e-02	2.47e-01	0.376	-0.065500	-0.19800	0.102000	-1.73e-01	2.27e-02	-0.215000	-0.078500	6.98e-02	7.23e-01	2.99e-02	3.72e-01	1.21e-01	7.84e-01	3.82e-02	3.26e-01	3.76e-01
REACTOME RECYCLING PATHWAY OF L1	20	5.04e-01	6.61e-01	0.376	-0.238000	0.09990	-0.016100	5.70e-02	-1.54e-01	0.081300	0.042400	1.97e-01	1.08e-01	4.49e-01	7.59e-01	6.60e-01	3.19e-01	5.53e-01	5.51e-01	9.07e-02
REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	25	2.26e-01	4.17e-01	0.375	0.003720	0.23500	-0.003410	2.40e-01	4.21e-03	0.085100	0.032800	1.39e-01	9.66e-01	8.47e-02	5.52e-01	3.86e-02	8.43e-01	6.01e-01	9.97e-01	9.00e-02
REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	12	7.73e-01	8.33e-01	0.374	-0.142000	0.07130	-0.156000	1.54e-01	-1.40e-01	-0.099000	0.032500	-1.90e-01	7.34e-01	5.15e-01	5.76e-01	4.51e-01	3.24e-01	9.85e-01	8.76e-01	1.84e-01
REACTOME GABA B RECEPTOR ACTIVATION	14	2.44e-01	4.31e-01	0.374	-0.149000	-0.04360	0.041500	-2.37e-01	1.18e-04	-0.224000	0.073900	4.29e-02	4.81e-01	5.04e-01	8.12e-01	1.76e-01	7.40e-01	7.37e-02	8.30e-01	5.28e-01
REACTOME FORMATION OF INCISION COMPLEX IN GG NER	18	4.35e-01	5.97e-01	0.372	0.036200	0.21300	0.217000	4.96e-03	4.50e-03	0.153000	0.133000	5.61e-02	9.39e-01	5.16e-02	1.54e-01	9.50e-01	8.87e-01	8.79e-02	4.23e-01	5.04e-01
REACTOME MRNA PROCESSING	141	7.83e-08	1.11e-06	0.372	-0.178000	0.06560	0.034200	-2.75e-04	4.04e-02	0.183000	0.251000	5.09e-02	2.53e-05	2.39e-01	7.98e-01	9.13e-01	6.21e-01	1.98e-04	2.04e-07	2.75e-01
REACTOME REGULATION OF INSULIN SECRETION	40	6.52e-02	1.90e-01	0.371	-0.175000	-0.11400	-0.082000	-9.70e-02	-1.55e-01	-0.230000	0.031100	1.05e-03	8.31e-02	1.64e-01	3.43e-01	2.29e-01	1.54e-01	2.30e-02	9.08e-01	7.93e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	11	5.83e-01	7.17e-01	0.371	-0.034500	-0.00476	0.085000	3.42e-02	-2.03e-01	-0.218000	-0.121000	1.57e-01	7.23e-01	9.68e-01	6.30e-01	8.19e-01	1.90e-01	1.75e-01	4.71e-01	3.55e-01
REACTOME METABOLISM OF RNA	218	1.04e-15	2.72e-14	0.370	-0.118000	0.12300	-0.029300	-9.40e-02	-1.41e-01	0.138000	0.238000	-5.03e-02	1.18e-04	3.30e-03	3.50e-01	1.87e-02	2.83e-05	3.51e-04	2.98e-10	2.15e-01
REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	21	4.66e-01	6.24e-01	0.370	0.010500	0.20200	0.023300	5.49e-02	-1.44e-02	0.198000	0.153000	-1.71e-01	8.99e-01	9.44e-02	8.79e-01	6.26e-01	7.81e-01	1.12e-01	2.16e-01	1.39e-01
REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	51	5.50e-02	1.67e-01	0.369	-0.239000	0.03910	0.009690	6.47e-02	-1.81e-01	0.053700	0.194000	-6.57e-03	1.98e-03	6.76e-01	7.68e-01	3.73e-01	1.92e-02	6.72e-01	1.95e-02	8.83e-01
REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS	42	5.46e-02	1.67e-01	0.368	-0.212000	-0.04650	-0.089100	-4.78e-02	-1.43e-01	-0.071800	0.215000	8.34e-02	5.22e-02	5.96e-01	2.90e-01	6.31e-01	9.68e-02	4.74e-01	2.74e-02	2.59e-01
REACTOME DNA REPAIR	71	1.38e-02	5.47e-02	0.368	-0.168000	0.11400	0.118000	5.00e-02	-6.37e-02	0.211000	0.171000	7.99e-03	1.42e-02	9.03e-02	9.91e-02	5.07e-01	5.30e-01	4.70e-04	1.43e-02	8.01e-01
REACTOME SULFUR AMINO ACID METABOLISM	19	3.59e-01	5.39e-01	0.367	0.120000	0.07720	0.077300	-2.95e-02	1.64e-01	0.117000	0.258000	2.25e-02	1.40e-01	5.47e-01	2.26e-01	8.47e-01	1.44e-01	4.10e-01	4.68e-02	7.25e-01
REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	14	8.00e-01	8.45e-01	0.366	-0.103000	0.09390	0.247000	1.40e-01	-4.15e-02	0.102000	0.079600	-1.25e-01	3.94e-01	5.31e-01	1.01e-01	3.29e-01	6.84e-01	5.15e-01	6.01e-01	3.71e-01
REACTOME ELONGATION ARREST AND RECOVERY	24	2.96e-01	4.72e-01	0.366	-0.224000	-0.03480	0.083600	-7.65e-02	-3.19e-02	0.226000	0.115000	-6.76e-02	3.16e-02	7.43e-01	4.85e-01	5.17e-01	6.53e-01	5.14e-02	3.21e-01	5.15e-01
REACTOME SIGNALLING TO RAS	20	2.48e-01	4.35e-01	0.366	0.006760	-0.06640	0.043400	-3.49e-02	-1.79e-01	-0.168000	0.201000	-1.61e-01	8.78e-01	5.78e-01	7.56e-01	8.00e-01	1.15e-01	1.56e-01	1.12e-01	1.74e-01
REACTOME LYSOSOME VESICLE BIOGENESIS	18	5.07e-01	6.64e-01	0.365	-0.276000	-0.03870	0.013700	1.95e-01	-6.05e-02	0.088400	0.061300	-4.74e-02	2.59e-02	7.61e-01	9.48e-01	1.37e-01	6.87e-01	5.41e-01	6.58e-01	6.93e-01
REACTOME G ALPHA Q SIGNALLING EVENTS	45	4.56e-02	1.44e-01	0.363	-0.148000	-0.22300	-0.074700	-1.29e-01	7.47e-02	-0.147000	-0.085400	5.39e-02	1.54e-01	4.01e-02	3.21e-01	2.23e-01	2.87e-01	9.15e-02	3.49e-01	3.12e-01
REACTOME G1 S TRANSITION	68	9.89e-05	7.06e-04	0.362	0.111000	0.16400	-0.036200	-4.24e-02	6.56e-03	0.269000	0.124000	-3.06e-02	1.47e-01	1.57e-02	5.47e-01	5.66e-01	9.92e-01	9.89e-05	5.04e-02	7.42e-01
REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	10	7.23e-01	8.03e-01	0.361	0.046800	-0.04550	-0.028400	2.65e-01	-1.61e-01	-0.044800	-0.122000	1.11e-01	9.09e-01	7.85e-01	8.48e-01	1.23e-01	3.10e-01	7.66e-01	4.86e-01	5.36e-01
REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	38	1.23e-01	2.87e-01	0.360	0.052800	0.25200	0.168000	1.00e-01	-5.92e-02	0.148000	0.012100	-1.11e-03	7.75e-01	5.08e-03	6.90e-02	2.45e-01	3.88e-01	1.15e-01	9.04e-01	9.46e-01
REACTOME CELL JUNCTION ORGANIZATION	29	1.91e-01	3.71e-01	0.359	0.003460	-0.07510	-0.142000	6.20e-02	-1.41e-01	-0.092100	-0.245000	-1.05e-01	4.34e-01	4.71e-01	9.79e-02	4.13e-01	2.99e-01	2.79e-01	2.81e-02	4.53e-01
REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES	43	1.13e-01	2.72e-01	0.357	-0.012900	0.20900	0.199000	1.07e-01	-1.72e-02	0.174000	0.033600	-3.42e-02	6.51e-01	1.37e-02	2.11e-02	1.86e-01	6.67e-01	4.66e-02	7.05e-01	6.38e-01
REACTOME HOST INTERACTIONS OF HIV FACTORS	100	3.77e-04	2.50e-03	0.357	0.031300	0.21200	0.029000	1.50e-02	3.38e-02	0.250000	0.130000	-1.47e-02	5.68e-01	3.50e-04	8.41e-01	7.76e-01	5.67e-01	1.90e-05	2.16e-02	9.78e-01
REACTOME BOTULINUM NEUROTOXICITY	10	7.56e-01	8.22e-01	0.356	-0.101000	0.04340	-0.178000	-2.94e-03	-1.78e-02	-0.034300	-0.096600	2.69e-01	4.78e-01	8.11e-01	2.94e-01	9.97e-01	8.33e-01	8.13e-01	5.81e-01	1.25e-01
REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	10	7.56e-01	8.22e-01	0.356	-0.101000	0.04340	-0.178000	-2.94e-03	-1.78e-02	-0.034300	-0.096600	2.69e-01	4.78e-01	8.11e-01	2.94e-01	9.97e-01	8.33e-01	8.13e-01	5.81e-01	1.25e-01
REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	10	7.48e-01	8.17e-01	0.355	-0.141000	-0.19200	0.161000	-1.69e-01	6.37e-02	-0.089100	0.051400	-5.31e-03	6.97e-01	1.11e-01	3.96e-01	5.17e-01	4.11e-01	4.40e-01	9.61e-01	7.11e-01
REACTOME ARMS MEDIATED ACTIVATION	14	6.71e-01	7.64e-01	0.355	0.036700	0.10700	-0.168000	-2.78e-03	-2.02e-01	-0.169000	-0.061900	-1.09e-01	9.46e-01	4.74e-01	2.40e-01	9.95e-01	1.42e-01	2.31e-01	6.74e-01	4.34e-01
REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	17	7.01e-01	7.86e-01	0.355	0.023200	0.00924	-0.108000	-7.77e-02	1.43e-01	0.077700	0.171000	2.27e-01	9.82e-01	9.56e-01	3.97e-01	5.79e-01	3.68e-01	5.95e-01	2.12e-01	9.21e-02
REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	46	1.59e-01	3.36e-01	0.354	0.085000	-0.24500	0.005820	-1.53e-01	1.73e-01	-0.058600	0.011800	4.14e-02	1.45e-01	3.63e-03	9.93e-01	7.98e-02	4.61e-02	4.41e-01	9.09e-01	6.65e-01
REACTOME SHC MEDIATED CASCADE	11	8.75e-01	9.14e-01	0.352	-0.054200	-0.11100	-0.026400	1.08e-01	-1.17e-01	-0.250000	0.007370	-1.42e-01	4.11e-01	6.82e-01	4.61e-01	8.14e-01	3.46e-01	3.59e-01	6.07e-01	6.02e-01
REACTOME ENOS ACTIVATION AND REGULATION	12	8.23e-01	8.63e-01	0.351	-0.031200	-0.21400	-0.216000	-6.94e-02	-3.63e-02	-0.131000	-0.078500	-2.67e-02	7.26e-01	1.74e-01	1.65e-01	6.79e-01	7.30e-01	3.85e-01	6.23e-01	8.41e-01
REACTOME S PHASE	72	4.56e-04	2.95e-03	0.351	0.086200	0.17600	0.009690	7.45e-03	-2.10e-02	0.262000	0.120000	-3.26e-02	1.68e-01	1.63e-02	9.29e-01	9.24e-01	8.09e-01	2.24e-04	4.65e-02	7.22e-01
REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	14	9.20e-01	9.50e-01	0.351	0.017300	-0.14100	0.001960	-2.09e-01	9.79e-02	-0.143000	0.146000	8.79e-02	9.74e-01	4.47e-01	9.19e-01	3.09e-01	6.32e-01	4.37e-01	4.66e-01	5.83e-01
REACTOME SIGNALLING TO ERKS	28	1.61e-01	3.37e-01	0.348	-0.005060	-0.09130	-0.147000	-7.68e-03	-1.81e-01	-0.235000	0.039500	-3.84e-02	7.70e-01	3.70e-01	1.45e-01	9.69e-01	5.96e-02	2.00e-02	7.17e-01	6.74e-01
REACTOME AXON GUIDANCE	145	2.23e-07	2.69e-06	0.347	-0.105000	0.05050	-0.026300	1.54e-01	-2.24e-01	-0.136000	-0.107000	4.59e-02	2.87e-02	3.02e-01	4.63e-01	6.48e-04	1.35e-06	2.70e-03	3.49e-02	2.93e-01
REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	18	6.03e-01	7.32e-01	0.346	0.222000	0.04630	-0.033200	-8.86e-02	-7.34e-03	-0.151000	-0.095600	1.65e-01	1.45e-01	7.31e-01	7.68e-01	5.12e-01	8.38e-01	2.24e-01	4.64e-01	2.13e-01
REACTOME NUCLEOTIDE EXCISION REPAIR	41	1.93e-01	3.73e-01	0.344	-0.170000	0.08680	0.135000	-8.23e-03	-1.22e-01	0.163000	0.151000	-8.81e-03	4.93e-02	3.07e-01	1.93e-01	7.25e-01	1.59e-01	4.82e-02	1.02e-01	9.84e-01
REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	33	3.66e-01	5.41e-01	0.344	0.190000	-0.04360	0.110000	1.26e-01	-2.65e-02	-0.227000	0.004050	-6.55e-03	1.52e-01	6.61e-01	2.42e-01	2.98e-01	6.21e-01	3.09e-02	8.46e-01	7.67e-01
REACTOME ERKS ARE INACTIVATED	11	7.39e-01	8.15e-01	0.344	0.002030	-0.11600	-0.225000	2.49e-02	-4.48e-02	-0.196000	0.113000	-2.15e-02	9.24e-01	4.98e-01	1.87e-01	8.70e-01	7.17e-01	2.43e-01	5.29e-01	8.78e-01
REACTOME G0 AND EARLY G1	11	8.00e-01	8.45e-01	0.344	-0.025600	-0.21200	0.056000	4.74e-02	-1.07e-01	-0.217000	0.083400	-4.31e-02	7.62e-01	1.96e-01	7.59e-01	7.58e-01	4.57e-01	1.77e-01	6.27e-01	7.70e-01
REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	29	6.64e-01	7.63e-01	0.343	0.267000	-0.00141	0.120000	6.44e-02	4.54e-02	-0.127000	-0.089800	3.90e-02	5.85e-02	7.95e-01	1.91e-01	8.90e-01	5.62e-01	4.66e-01	6.94e-01	7.48e-01
REACTOME APOPTOTIC EXECUTION PHASE	30	2.36e-01	4.21e-01	0.341	-0.203000	-0.05400	0.105000	1.74e-01	-8.13e-02	-0.006020	-0.120000	9.90e-02	1.47e-01	5.97e-01	2.86e-01	9.31e-02	6.42e-01	9.03e-01	3.33e-01	3.69e-01
REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	49	1.22e-01	2.86e-01	0.341	-0.114000	-0.06260	-0.144000	1.78e-02	-2.28e-01	-0.129000	-0.095800	-3.73e-03	1.85e-01	2.59e-01	8.14e-02	8.72e-01	1.63e-02	1.28e-01	2.81e-01	9.75e-01
REACTOME IL 2 SIGNALING	29	6.22e-01	7.46e-01	0.340	-0.188000	0.04020	0.081100	-4.36e-02	-1.56e-01	0.087000	0.179000	-7.92e-02	4.24e-01	7.27e-01	4.90e-01	5.02e-01	3.24e-01	4.66e-01	6.81e-02	4.41e-01
REACTOME CELL CELL COMMUNICATION	56	1.27e-01	2.93e-01	0.340	-0.116000	-0.09050	-0.151000	1.08e-02	-1.30e-01	-0.138000	-0.185000	-2.79e-02	6.07e-01	2.30e-01	2.72e-02	7.51e-01	2.12e-01	4.37e-02	2.39e-02	8.80e-01
REACTOME RNA POL III TRANSCRIPTION TERMINATION	18	5.50e-01	6.93e-01	0.339	0.116000	0.09420	0.091500	-1.15e-01	-4.38e-02	0.068300	0.090000	-2.37e-01	5.02e-01	4.76e-01	5.05e-01	3.90e-01	6.32e-01	6.36e-01	5.01e-01	5.99e-02
REACTOME IRON UPTAKE AND TRANSPORT	23	3.55e-01	5.36e-01	0.339	0.087300	0.10200	-0.091000	-5.22e-02	-1.79e-05	-0.035100	0.148000	2.50e-01	6.08e-01	3.84e-01	4.03e-01	6.73e-01	8.66e-01	7.14e-01	2.08e-01	3.10e-02
REACTOME NOD1 2 SIGNALING PATHWAY	21	9.84e-01	9.92e-01	0.338	-0.213000	-0.06460	0.055000	-6.00e-02	-1.34e-01	-0.124000	0.133000	-8.55e-02	3.91e-01	6.51e-01	7.41e-01	9.64e-01	5.65e-01	6.77e-01	7.05e-01	5.66e-01
REACTOME REGULATORY RNA PATHWAYS	21	3.27e-01	5.07e-01	0.336	-0.179000	-0.01580	0.168000	-2.21e-02	-1.63e-01	0.152000	0.047700	8.83e-05	9.88e-02	8.83e-01	1.75e-01	8.78e-01	1.37e-01	2.27e-01	7.04e-01	9.68e-01
REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	18	3.86e-01	5.63e-01	0.334	-0.277000	0.06860	-0.108000	2.26e-02	-1.28e-02	-0.009470	0.076500	-1.07e-01	5.71e-02	6.17e-01	3.97e-01	8.44e-01	8.12e-01	9.03e-01	5.79e-01	3.96e-01
REACTOME GPCR DOWNSTREAM SIGNALING	116	1.62e-04	1.12e-03	0.333	-0.114000	-0.15800	-0.068800	-1.50e-02	-6.77e-02	-0.178000	-0.128000	1.23e-01	1.97e-01	7.01e-03	1.36e-01	7.84e-01	3.34e-01	1.79e-03	1.15e-02	1.01e-02
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE	22	5.52e-01	6.93e-01	0.332	-0.157000	-0.12600	0.175000	1.07e-01	-5.63e-02	-0.153000	-0.000365	-3.46e-02	2.94e-01	2.31e-01	3.20e-01	3.77e-01	9.54e-01	3.11e-01	8.63e-01	8.17e-01
REACTOME IL 3 5 AND GM CSF SIGNALING	29	6.95e-01	7.81e-01	0.329	-0.197000	0.03980	-0.088200	-9.08e-02	-1.76e-01	0.080500	0.110000	-4.85e-02	3.84e-01	8.95e-01	4.07e-01	2.68e-01	3.91e-01	6.19e-01	3.12e-01	6.31e-01
REACTOME METABOLISM OF PROTEINS	310	3.26e-17	1.08e-15	0.329	-0.116000	0.09550	-0.007340	-1.27e-01	-7.18e-02	0.106000	0.216000	-8.22e-02	1.90e-04	2.52e-03	8.65e-01	2.00e-04	1.36e-02	1.14e-03	4.28e-11	6.19e-03
REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION	36	5.63e-02	1.67e-01	0.328	-0.168000	0.08640	0.036500	-1.09e-02	1.07e-02	0.053300	0.223000	1.33e-01	2.45e-02	3.10e-01	8.34e-01	7.22e-01	7.79e-01	6.15e-01	1.92e-02	2.03e-01
REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX	28	2.62e-01	4.46e-01	0.328	-0.159000	-0.00245	0.103000	-1.51e-01	-1.99e-03	0.188000	-0.004070	-1.15e-01	8.51e-02	9.67e-01	3.45e-01	1.57e-01	8.38e-01	8.10e-02	9.61e-01	2.45e-01
REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	47	1.43e-01	3.17e-01	0.327	-0.097100	-0.04800	-0.250000	-3.63e-02	-6.71e-02	-0.023500	-0.132000	9.46e-02	4.97e-01	5.33e-01	1.38e-03	8.44e-01	8.47e-01	6.74e-01	1.70e-01	1.60e-01
REACTOME G1 PHASE	25	3.94e-01	5.67e-01	0.326	-0.156000	0.11600	-0.163000	8.72e-02	-1.62e-01	-0.022300	0.069200	-5.60e-02	1.10e-01	3.00e-01	1.28e-01	4.09e-01	1.07e-01	7.91e-01	5.44e-01	5.77e-01
REACTOME RNA POL I TRANSCRIPTION INITIATION	23	6.92e-01	7.81e-01	0.325	-0.019200	0.16600	0.192000	-3.55e-02	-6.95e-02	0.126000	0.122000	-5.95e-02	7.01e-01	1.51e-01	1.03e-01	7.81e-01	4.48e-01	2.98e-01	3.03e-01	5.71e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX	53	3.45e-02	1.15e-01	0.324	0.140000	0.03070	-0.038600	9.87e-02	-1.80e-01	-0.185000	-0.080300	-6.83e-03	7.27e-02	7.62e-01	5.25e-01	2.47e-01	2.46e-02	1.79e-02	5.07e-01	8.35e-01
REACTOME RNA POL I TRANSCRIPTION	26	6.21e-01	7.46e-01	0.321	-0.090000	0.12500	0.154000	-1.68e-02	-1.22e-01	0.126000	0.154000	-3.16e-02	2.97e-01	2.52e-01	1.67e-01	9.03e-01	2.00e-01	2.71e-01	1.64e-01	7.33e-01
REACTOME TRANSCRIPTION COUPLED NER TC NER	37	4.73e-01	6.31e-01	0.321	-0.198000	0.04960	0.102000	-6.72e-03	-1.07e-01	0.154000	0.127000	-1.55e-02	6.61e-02	4.97e-01	3.68e-01	7.29e-01	2.67e-01	1.11e-01	1.62e-01	9.68e-01
REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	14	6.67e-01	7.63e-01	0.320	0.270000	0.07850	-0.065400	8.38e-02	-3.24e-02	0.012000	-0.104000	1.56e-02	1.10e-01	6.02e-01	6.32e-01	5.52e-01	7.29e-01	9.72e-01	4.81e-01	9.41e-01
REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	32	2.71e-01	4.53e-01	0.319	0.146000	-0.04050	-0.039700	1.17e-01	-1.67e-01	-0.184000	-0.041400	-2.31e-02	3.49e-01	6.67e-01	7.38e-01	2.24e-01	6.56e-02	8.72e-02	8.36e-01	7.75e-01
REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	22	6.65e-01	7.63e-01	0.319	-0.089800	0.13100	-0.071000	-1.67e-02	-1.98e-01	-0.003180	0.151000	9.75e-02	7.60e-01	4.16e-01	5.23e-01	9.18e-01	1.19e-01	7.73e-01	3.02e-01	4.59e-01
REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	19	6.35e-01	7.48e-01	0.317	0.176000	-0.16100	0.121000	5.26e-02	2.20e-02	-0.124000	0.010800	1.01e-01	2.52e-01	1.96e-01	3.60e-01	6.56e-01	9.86e-01	3.00e-01	9.40e-01	4.43e-01
REACTOME DAG AND IP3 SIGNALING	17	5.82e-01	7.17e-01	0.317	-0.219000	-0.08360	0.165000	8.97e-02	-2.80e-02	-0.037500	0.039300	-7.82e-02	3.25e-01	3.34e-01	2.61e-01	3.29e-01	6.18e-01	6.31e-01	8.08e-01	7.68e-01
REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	17	8.99e-01	9.32e-01	0.316	-0.215000	0.06360	-0.130000	5.31e-02	-1.59e-01	0.044000	0.008640	-5.18e-02	1.30e-01	9.32e-01	3.28e-01	6.80e-01	3.16e-01	8.15e-01	9.57e-01	6.77e-01
REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	22	7.40e-01	8.15e-01	0.315	-0.009040	0.06550	0.224000	-3.89e-02	5.88e-02	0.111000	0.166000	-1.54e-02	7.71e-01	5.87e-01	6.28e-02	7.64e-01	7.46e-01	3.74e-01	1.67e-01	8.62e-01
REACTOME MRNA CAPPING	28	3.61e-01	5.39e-01	0.315	-0.103000	0.02170	0.080400	-1.52e-01	6.25e-02	0.187000	-0.012400	-1.40e-01	2.30e-01	8.48e-01	4.70e-01	1.53e-01	6.89e-01	8.33e-02	8.98e-01	1.60e-01
REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	29	4.05e-01	5.78e-01	0.315	0.008140	0.19900	0.022200	1.13e-01	5.11e-02	0.147000	0.031000	1.46e-01	9.59e-01	1.19e-01	7.62e-01	3.02e-01	5.26e-01	2.27e-01	9.77e-01	6.90e-02
REACTOME SIGNALING BY RHO GTPASES	70	1.09e-01	2.68e-01	0.315	-0.075600	-0.04240	-0.070600	2.31e-02	-1.69e-01	-0.155000	-0.166000	-7.93e-02	6.19e-01	4.01e-01	1.88e-01	7.04e-01	5.95e-02	2.55e-02	2.52e-02	1.96e-01
REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	37	2.13e-01	4.04e-01	0.314	-0.183000	0.05850	0.043500	-9.25e-02	3.81e-02	0.215000	0.059300	-1.47e-02	2.20e-02	5.97e-01	6.76e-01	2.11e-01	9.40e-01	4.08e-02	5.34e-01	8.29e-01
REACTOME MITOTIC G2 G2 M PHASES	49	9.11e-02	2.40e-01	0.313	-0.019300	0.16000	0.203000	1.04e-01	-4.73e-02	0.130000	-0.025200	-2.12e-02	5.74e-01	4.44e-02	1.22e-02	1.73e-01	4.05e-01	1.18e-01	7.43e-01	7.39e-01
REACTOME RNA POL III TRANSCRIPTION	31	4.21e-01	5.87e-01	0.311	-0.022600	0.13300	-0.077500	-2.85e-02	-3.27e-02	0.189000	0.133000	-1.32e-01	7.85e-01	2.52e-01	3.68e-01	8.05e-01	7.38e-01	1.10e-01	2.29e-01	2.63e-01
REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	23	2.53e-01	4.37e-01	0.310	-0.132000	-0.18400	-0.035600	-1.11e-01	-3.89e-02	0.126000	-0.098500	6.56e-02	3.21e-01	1.13e-01	9.58e-01	2.88e-01	8.41e-01	3.09e-01	2.90e-01	6.01e-01
REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA	18	1.50e-01	3.26e-01	0.310	-0.107000	0.07550	0.004710	-2.34e-01	-1.22e-01	-0.028400	-0.082400	-4.02e-02	2.06e-01	4.85e-01	8.41e-01	2.62e-02	1.74e-01	7.68e-01	5.39e-01	5.54e-01
REACTOME CIRCADIAN CLOCK	43	4.56e-02	1.44e-01	0.310	0.196000	-0.05190	0.079300	1.72e-01	-4.78e-02	-0.077800	0.031400	9.82e-02	8.18e-02	5.26e-01	3.14e-01	3.92e-02	4.37e-01	4.36e-01	5.80e-01	2.67e-01
REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	17	6.77e-01	7.68e-01	0.307	0.254000	0.04120	-0.028900	6.28e-02	4.91e-03	-0.002300	-0.063700	1.37e-01	9.91e-02	7.68e-01	7.99e-01	6.19e-01	9.13e-01	9.45e-01	6.34e-01	3.16e-01
REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM	131	5.38e-04	3.38e-03	0.306	0.146000	-0.15600	0.018400	-4.25e-02	1.25e-01	-0.057200	-0.137000	9.14e-02	4.95e-03	1.66e-03	9.31e-01	4.70e-01	1.22e-02	3.39e-01	3.42e-03	4.57e-02
REACTOME INTERFERON SIGNALING	94	9.80e-02	2.47e-01	0.305	-0.126000	0.18700	0.034000	1.26e-01	-9.42e-02	0.115000	0.051400	-1.90e-02	2.05e-01	3.35e-03	7.59e-01	6.49e-02	4.81e-01	9.37e-03	2.87e-01	9.92e-01
REACTOME G ALPHA1213 SIGNALLING EVENTS	45	1.61e-01	3.37e-01	0.304	-0.096800	-0.12900	-0.030300	-6.74e-03	-9.64e-02	-0.142000	-0.158000	1.07e-01	4.03e-01	1.24e-01	5.62e-01	9.71e-01	2.61e-01	8.05e-02	6.66e-02	2.24e-01
REACTOME SIGNALING BY BMP	17	2.76e-01	4.59e-01	0.303	0.116000	-0.15700	0.085100	7.28e-02	-1.08e-01	-0.033200	-0.137000	9.93e-02	5.18e-01	2.34e-01	5.49e-01	5.67e-01	3.52e-01	7.64e-01	3.09e-01	4.75e-01
REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	14	5.32e-01	6.82e-01	0.302	-0.174000	0.03800	-0.066200	1.04e-01	1.20e-01	0.078200	-0.032900	-1.50e-01	1.87e-01	8.05e-01	6.28e-01	4.64e-01	5.05e-01	6.27e-01	8.20e-01	2.88e-01
REACTOME PKB MEDIATED EVENTS	28	2.64e-01	4.48e-01	0.301	0.196000	0.04550	0.041400	5.08e-02	5.28e-02	0.136000	0.105000	1.15e-01	7.42e-02	6.80e-01	7.32e-01	6.07e-01	7.61e-01	2.21e-01	3.99e-01	2.92e-01
REACTOME CD28 CO STIMULATION	22	6.40e-01	7.50e-01	0.301	-0.177000	-0.14500	-0.160000	-6.77e-02	-7.13e-03	0.057000	-0.020800	6.37e-02	1.72e-01	1.29e-01	1.69e-01	5.94e-01	8.86e-01	8.10e-01	6.91e-01	6.21e-01
REACTOME INNATE IMMUNE SYSTEM	130	1.85e-03	9.90e-03	0.298	-0.137000	0.03300	-0.136000	8.91e-02	-1.82e-01	-0.028700	0.091700	-2.99e-03	2.45e-02	5.15e-01	6.23e-03	4.73e-02	1.21e-03	9.44e-01	1.26e-01	9.73e-01
REACTOME PLC BETA MEDIATED EVENTS	21	5.73e-01	7.11e-01	0.298	-0.238000	-0.08980	0.107000	2.70e-02	-5.76e-02	-0.050800	-0.024000	-7.29e-02	1.54e-01	2.93e-01	4.18e-01	6.17e-01	9.10e-01	5.40e-01	4.86e-01	7.21e-01
REACTOME GROWTH HORMONE RECEPTOR SIGNALING	19	9.52e-01	9.72e-01	0.296	-0.036700	0.04160	-0.101000	1.43e-02	-2.31e-01	-0.016100	0.144000	-8.24e-04	9.51e-01	9.83e-01	4.55e-01	7.58e-01	4.67e-01	9.75e-01	4.23e-01	9.68e-01
REACTOME SPHINGOLIPID METABOLISM	39	4.64e-01	6.23e-01	0.296	-0.176000	-0.01890	0.005550	1.45e-01	-8.61e-02	0.086500	-0.047700	-1.35e-01	6.82e-02	9.19e-01	8.32e-01	1.73e-01	3.40e-01	2.69e-01	6.46e-01	1.66e-01
REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	16	9.19e-01	9.50e-01	0.296	-0.009900	0.13700	-0.028000	1.48e-01	1.05e-02	0.192000	-0.082400	-5.09e-02	8.79e-01	2.13e-01	9.63e-01	4.60e-01	8.57e-01	2.49e-01	7.29e-01	8.98e-01
REACTOME HIV INFECTION	158	9.70e-04	5.78e-03	0.295	-0.048900	0.14100	0.044100	2.47e-02	3.41e-02	0.231000	0.088200	-1.25e-02	1.88e-01	3.29e-03	4.86e-01	6.35e-01	6.63e-01	1.16e-06	5.34e-02	9.28e-01
REACTOME MEMBRANE TRAFFICKING	94	7.69e-03	3.42e-02	0.295	-0.140000	0.02500	0.022900	8.84e-03	-1.10e-01	0.069300	0.221000	-1.71e-02	8.10e-03	7.20e-01	6.28e-01	8.23e-01	3.95e-02	3.36e-01	2.11e-04	7.00e-01
REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	22	6.06e-01	7.34e-01	0.294	0.156000	-0.09170	-0.133000	1.56e-02	6.66e-03	-0.171000	-0.037400	7.14e-02	1.17e-01	4.46e-01	1.92e-01	9.10e-01	7.97e-01	1.26e-01	9.44e-01	4.97e-01
REACTOME PI 3K CASCADE	35	1.80e-01	3.65e-01	0.292	-0.116000	-0.18600	-0.015300	-2.71e-02	5.78e-02	-0.111000	0.007640	1.43e-01	9.23e-02	6.06e-02	6.14e-01	6.29e-01	7.03e-01	3.73e-01	7.50e-01	8.92e-02
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	62	6.47e-02	1.89e-01	0.290	-0.052000	-0.01010	-0.196000	9.69e-02	-9.76e-02	-0.117000	0.002860	1.01e-01	9.65e-01	4.08e-01	2.56e-02	2.29e-01	3.92e-01	5.50e-02	7.36e-01	3.03e-02
REACTOME DEVELOPMENTAL BIOLOGY	245	2.42e-08	3.94e-07	0.287	-0.055100	0.01310	-0.060400	1.53e-01	-1.67e-01	-0.125000	-0.077400	4.85e-02	2.33e-01	9.83e-01	1.21e-01	2.97e-05	8.08e-06	2.16e-04	6.16e-02	8.43e-02
REACTOME PI3K EVENTS IN ERBB4 SIGNALING	28	4.15e-01	5.82e-01	0.287	-0.053300	-0.13400	0.049200	-4.21e-02	7.91e-02	-0.080200	0.087900	1.92e-01	4.60e-01	1.91e-01	6.72e-01	7.12e-01	5.78e-01	4.02e-01	4.13e-01	6.95e-02
REACTOME PERK REGULATED GENE EXPRESSION	22	7.28e-01	8.07e-01	0.286	-0.077900	-0.07540	-0.072900	-5.84e-02	-1.66e-01	0.010800	-0.020600	1.82e-01	2.56e-01	7.97e-01	6.30e-01	7.88e-01	2.89e-01	6.33e-01	8.31e-01	2.62e-01
REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	11	9.35e-01	9.62e-01	0.285	-0.178000	-0.00578	-0.046900	6.95e-02	-1.41e-01	0.027800	0.022600	1.46e-01	2.33e-01	9.63e-01	7.54e-01	6.59e-01	3.45e-01	8.99e-01	8.99e-01	3.89e-01
REACTOME PROCESSING OF INTRONLESS PRE MRNAS	13	3.94e-01	5.67e-01	0.285	-0.080000	0.04940	-0.015900	-2.20e-01	-1.94e-02	0.032200	-0.141000	5.08e-02	3.22e-01	6.46e-01	7.05e-01	5.20e-02	5.67e-01	8.77e-01	3.81e-01	9.67e-01
REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	17	8.00e-01	8.45e-01	0.284	-0.157000	-0.01830	-0.162000	4.57e-02	-5.44e-02	0.095000	-0.069200	-1.04e-01	1.84e-01	8.80e-01	2.12e-01	7.11e-01	5.87e-01	5.08e-01	6.05e-01	4.10e-01
REACTOME SYNTHESIS OF PC	10	7.95e-01	8.45e-01	0.284	0.192000	-0.12800	0.005550	-9.74e-03	9.62e-02	-0.058700	0.083200	-8.88e-02	1.29e-01	4.77e-01	9.98e-01	9.74e-01	3.81e-01	7.21e-01	6.93e-01	6.06e-01
REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	60	3.15e-02	1.07e-01	0.284	-0.115000	0.03330	0.103000	8.36e-02	-1.21e-01	-0.180000	0.009490	-3.98e-02	1.91e-01	5.88e-01	1.58e-01	1.58e-01	5.43e-02	1.19e-02	7.75e-01	4.47e-01
REACTOME METABOLISM OF VITAMINS AND COFACTORS	37	4.09e-01	5.80e-01	0.284	0.148000	0.00385	-0.101000	-1.86e-01	2.53e-02	-0.066700	0.079000	4.94e-02	3.38e-01	8.66e-01	2.56e-01	4.67e-02	9.10e-01	7.44e-01	3.41e-01	7.74e-01
REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	42	3.12e-01	4.89e-01	0.281	0.035200	-0.04310	-0.001310	4.37e-02	-1.13e-01	-0.227000	-0.071400	6.93e-02	4.88e-01	5.19e-01	8.16e-01	4.80e-01	1.49e-01	4.05e-02	5.29e-01	2.84e-01
REACTOME PURINE METABOLISM	27	3.65e-01	5.41e-01	0.280	0.002740	-0.05750	0.209000	-1.19e-01	-7.56e-03	0.069400	0.087400	6.90e-02	9.49e-01	8.22e-01	6.47e-02	2.93e-01	8.32e-01	2.24e-01	3.09e-01	3.80e-01
REACTOME RNA POL II TRANSCRIPTION	85	1.00e-02	4.13e-02	0.279	-0.179000	0.04180	0.022600	-2.88e-02	3.74e-02	0.153000	0.126000	4.66e-02	4.88e-04	5.11e-01	8.40e-01	4.39e-01	9.90e-01	2.32e-02	4.36e-02	5.50e-01
REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	17	8.98e-01	9.32e-01	0.279	0.155000	-0.05150	0.137000	-2.80e-02	1.94e-04	-0.167000	-0.050800	3.19e-02	3.50e-01	6.89e-01	3.25e-01	8.56e-01	8.86e-01	1.92e-01	7.03e-01	8.38e-01
REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT	101	6.17e-03	2.91e-02	0.278	0.150000	-0.00712	0.057900	3.25e-02	4.81e-02	-0.171000	0.025300	1.35e-01	3.23e-02	6.79e-01	5.87e-01	7.02e-01	5.87e-01	1.22e-03	8.34e-01	1.06e-02
REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	28	9.67e-01	9.81e-01	0.278	-0.207000	-0.01240	0.023300	-6.51e-02	-1.34e-01	-0.069600	0.079900	-1.82e-02	2.04e-01	9.53e-01	9.14e-01	8.16e-01	3.82e-01	8.57e-01	8.85e-01	9.18e-01
REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	30	4.35e-01	5.97e-01	0.278	-0.010300	0.19500	-0.014800	8.39e-02	6.60e-02	0.119000	0.011400	1.14e-01	8.87e-01	1.18e-01	5.05e-01	4.44e-01	4.33e-01	3.39e-01	8.70e-01	1.30e-01
REACTOME PPARA ACTIVATES GENE EXPRESSION	81	8.13e-02	2.23e-01	0.276	0.093300	-0.10700	-0.032300	3.03e-02	7.28e-02	-0.145000	-0.117000	1.19e-01	3.51e-01	7.79e-02	3.87e-01	5.26e-01	3.86e-01	2.19e-02	7.50e-02	3.53e-02
REACTOME HIV LIFE CYCLE	94	9.51e-02	2.46e-01	0.275	-0.133000	0.13000	0.055500	7.23e-02	-1.63e-02	0.163000	0.076300	1.06e-02	8.11e-03	4.59e-02	5.30e-01	2.63e-01	5.24e-01	1.27e-02	2.46e-01	7.51e-01
REACTOME TRANSCRIPTION	126	4.25e-03	2.04e-02	0.274	-0.136000	0.07020	-0.001740	-8.76e-04	1.25e-02	0.158000	0.161000	3.16e-02	1.27e-03	1.97e-01	8.11e-01	8.18e-01	7.63e-01	5.14e-03	1.94e-03	5.39e-01
REACTOME ASPARAGINE N LINKED GLYCOSYLATION	66	2.89e-01	4.65e-01	0.274	-0.144000	0.12800	-0.005030	1.19e-01	-1.39e-01	0.028500	0.041700	-4.31e-02	5.14e-02	7.97e-02	9.62e-01	3.87e-02	7.81e-02	7.60e-01	4.94e-01	4.65e-01
REACTOME SIGNALING BY NOTCH1	52	3.96e-01	5.67e-01	0.274	-0.077600	0.02250	-0.011900	1.23e-01	-1.90e-01	-0.120000	0.024300	-4.50e-02	4.42e-01	8.75e-01	8.69e-01	8.42e-02	1.94e-02	1.95e-01	8.79e-01	4.79e-01
REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	170	1.33e-06	1.31e-05	0.274	0.148000	0.11100	0.059200	-2.64e-02	5.13e-02	0.162000	0.064500	-5.86e-02	3.73e-03	1.28e-02	1.10e-01	5.95e-01	3.33e-01	4.41e-05	1.69e-01	2.17e-01
REACTOME PRE NOTCH EXPRESSION AND PROCESSING	32	5.34e-01	6.82e-01	0.273	-0.096600	-0.07190	-0.125000	1.70e-01	-8.61e-02	-0.049200	-0.066700	3.46e-02	3.47e-01	4.55e-01	1.90e-01	7.97e-02	2.96e-01	5.71e-01	5.01e-01	7.62e-01
REACTOME RNA POL II PRE TRANSCRIPTION EVENTS	49	2.37e-01	4.21e-01	0.272	-0.172000	0.00218	0.033100	-4.66e-02	5.42e-02	0.187000	0.058800	-8.65e-03	1.32e-02	9.29e-01	7.24e-01	4.39e-01	8.48e-01	3.92e-02	4.77e-01	8.64e-01
REACTOME ACTIVATION OF GENES BY ATF4	19	7.88e-01	8.40e-01	0.272	-0.036500	-0.10500	-0.031300	-8.54e-02	-1.44e-01	-0.011600	-0.012200	1.80e-01	2.57e-01	6.58e-01	7.46e-01	7.86e-01	3.34e-01	7.54e-01	8.60e-01	2.95e-01
REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	37	2.09e-01	4.00e-01	0.271	-0.065800	-0.16700	0.072800	1.50e-01	-4.53e-02	-0.072700	-0.011800	7.65e-02	3.25e-01	6.17e-02	4.55e-01	9.01e-02	4.82e-01	3.80e-01	8.89e-01	4.25e-01
REACTOME NUCLEAR SIGNALING BY ERBB4	22	6.26e-01	7.48e-01	0.270	0.005130	0.00165	0.090100	-1.39e-01	-9.63e-02	-0.055800	0.166000	7.49e-02	9.58e-01	9.98e-01	4.79e-01	3.41e-01	2.63e-01	8.07e-01	1.78e-01	5.56e-01
REACTOME HEMOSTASIS	234	3.53e-05	2.60e-04	0.270	-0.131000	-0.07610	-0.082600	-4.25e-04	-1.40e-01	-0.136000	-0.072700	-5.48e-03	1.36e-02	3.22e-02	2.80e-02	9.65e-01	2.71e-03	1.34e-04	8.78e-02	9.86e-01
REACTOME MITOTIC G1 G1 S PHASES	83	7.97e-03	3.51e-02	0.270	0.026800	0.12400	-0.039000	-7.50e-03	-4.92e-02	0.188000	0.118000	-5.89e-02	8.41e-01	4.48e-02	4.75e-01	9.50e-01	3.40e-01	2.98e-03	4.15e-02	3.80e-01
REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	54	3.39e-01	5.21e-01	0.270	0.050600	0.16300	0.015400	1.14e-01	2.22e-02	0.099800	0.110000	8.76e-02	3.89e-01	9.08e-02	7.94e-01	1.77e-01	6.24e-01	1.63e-01	2.59e-01	1.81e-01
REACTOME PROTEIN FOLDING	40	3.14e-01	4.90e-01	0.268	0.014500	0.13400	0.059600	-5.39e-03	3.57e-02	0.047200	0.194000	-9.49e-02	8.95e-01	1.27e-01	5.32e-01	9.84e-01	8.59e-01	6.43e-01	3.00e-02	2.47e-01
REACTOME ERK MAPK TARGETS	19	6.94e-01	7.81e-01	0.265	0.143000	-0.05080	-0.101000	4.94e-02	-6.03e-02	-0.168000	-0.012300	4.97e-02	1.53e-01	6.93e-01	3.27e-01	7.14e-01	8.24e-01	1.61e-01	8.66e-01	6.35e-01
REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION	56	4.80e-01	6.38e-01	0.264	-0.060300	0.11300	0.010000	5.29e-04	-1.70e-02	0.177000	0.133000	-5.93e-02	3.23e-01	1.69e-01	9.76e-01	9.55e-01	7.26e-01	3.31e-02	9.24e-02	5.08e-01
REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	28	6.63e-01	7.63e-01	0.259	-0.177000	-0.01810	0.067000	-4.10e-02	-4.38e-02	0.164000	0.009770	-2.37e-02	1.34e-01	8.94e-01	6.76e-01	5.52e-01	6.48e-01	8.70e-02	9.73e-01	9.47e-01
REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	82	2.41e-02	8.60e-02	0.258	0.076800	0.07080	-0.005040	-5.52e-02	5.02e-02	0.191000	0.117000	8.78e-04	3.17e-01	2.61e-01	8.81e-01	4.01e-01	5.11e-01	2.66e-03	4.42e-02	9.00e-01
REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	17	9.41e-01	9.63e-01	0.257	0.042000	0.01270	-0.101000	-6.81e-02	1.20e-01	0.025500	0.065900	1.73e-01	9.10e-01	9.35e-01	4.28e-01	6.29e-01	4.64e-01	8.88e-01	6.34e-01	2.03e-01
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION	107	7.32e-02	2.06e-01	0.256	-0.130000	0.10400	-0.026100	8.33e-02	-1.47e-01	-0.057700	0.037400	-6.46e-02	7.16e-02	4.09e-02	7.09e-01	8.38e-02	1.46e-02	3.78e-01	6.36e-01	2.06e-01
REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	73	2.49e-03	1.26e-02	0.256	0.097400	0.09150	0.026600	-8.11e-02	-7.16e-02	0.182000	0.044800	1.57e-02	2.53e-01	1.71e-01	8.75e-01	3.11e-01	2.57e-01	6.21e-03	5.31e-01	7.20e-01
REACTOME METABOLISM OF NON CODING RNA	42	5.56e-01	6.97e-01	0.256	0.023100	0.19400	-0.081200	8.40e-02	-3.92e-02	0.058700	0.071400	6.14e-02	7.31e-01	5.51e-02	3.50e-01	4.13e-01	5.39e-01	4.37e-01	3.34e-01	3.06e-01
REACTOME TRIF MEDIATED TLR3 SIGNALING	56	8.68e-02	2.31e-01	0.255	0.036600	-0.02220	-0.151000	1.28e-02	-4.17e-02	-0.131000	0.117000	8.71e-02	6.34e-01	9.95e-01	3.35e-02	6.83e-01	6.77e-01	1.11e-01	1.24e-01	1.79e-01
REACTOME PIP3 ACTIVATES AKT SIGNALING	25	6.35e-01	7.48e-01	0.254	-0.045600	-0.13600	0.043500	-5.62e-02	4.67e-02	-0.127000	0.059600	1.31e-01	5.28e-01	2.10e-01	7.27e-01	6.33e-01	8.11e-01	2.22e-01	6.02e-01	2.49e-01
REACTOME MITOTIC M M G1 PHASES	99	1.75e-02	6.54e-02	0.254	0.072500	0.15100	-0.009700	-2.03e-02	-2.99e-03	0.162000	0.066800	-7.32e-02	2.25e-01	2.47e-02	9.93e-01	7.33e-01	9.25e-01	5.53e-03	1.51e-01	2.91e-01
REACTOME SIGNALING BY GPCR	159	6.68e-03	3.06e-02	0.254	-0.072900	-0.11800	-0.065200	-2.31e-03	-6.21e-02	-0.160000	-0.094100	5.15e-02	3.04e-01	1.49e-02	1.52e-01	7.58e-01	2.84e-01	1.14e-03	6.06e-02	1.74e-01
REACTOME ACTIVATED TLR4 SIGNALLING	66	1.11e-01	2.72e-01	0.253	0.025800	-0.05040	-0.161000	4.96e-02	-5.33e-02	-0.149000	0.072400	5.01e-02	7.17e-01	7.75e-01	2.40e-02	4.37e-01	4.79e-01	6.87e-02	3.13e-01	3.91e-01
REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK	64	2.28e-01	4.19e-01	0.253	-0.100000	-0.14300	-0.065400	-9.70e-02	-3.01e-03	-0.138000	-0.024000	1.98e-02	3.34e-01	1.36e-01	2.61e-01	2.60e-01	8.56e-01	5.12e-02	9.40e-01	5.30e-01
REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	35	5.32e-01	6.82e-01	0.251	-0.139000	0.00122	0.081000	-8.37e-02	2.60e-02	0.155000	0.019600	-7.03e-02	8.54e-02	9.94e-01	4.15e-01	3.90e-01	9.49e-01	1.10e-01	8.46e-01	4.15e-01
REACTOME PRE NOTCH PROCESSING IN GOLGI	15	9.41e-01	9.63e-01	0.251	-0.015600	0.00749	-0.101000	1.39e-01	-2.94e-02	-0.025300	-0.139000	1.12e-01	8.81e-01	9.70e-01	4.71e-01	3.33e-01	7.44e-01	8.27e-01	3.51e-01	4.62e-01
REACTOME SIGNALING BY NOTCH	77	1.71e-01	3.56e-01	0.251	-0.087500	-0.01640	-0.062100	1.26e-01	-1.49e-01	-0.113000	-0.015300	-1.35e-02	2.60e-01	7.09e-01	3.15e-01	3.45e-02	2.20e-02	1.11e-01	7.02e-01	7.39e-01
REACTOME CELL CYCLE MITOTIC	192	2.14e-03	1.11e-02	0.251	-0.001410	0.15200	0.042500	1.98e-02	-4.78e-02	0.143000	0.098000	-7.25e-02	7.91e-01	1.07e-03	2.62e-01	6.18e-01	1.81e-01	1.20e-03	9.42e-03	9.36e-02
REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	25	5.37e-01	6.84e-01	0.250	-0.020400	-0.09780	0.000193	6.09e-02	3.58e-02	0.087300	0.198000	2.90e-02	9.85e-01	3.95e-01	9.95e-01	3.83e-01	5.55e-01	4.92e-01	7.93e-02	8.35e-01
REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	33	6.21e-01	7.46e-01	0.250	0.026000	0.04910	0.037600	2.03e-01	-8.65e-02	-0.051200	0.037400	-7.27e-02	8.34e-01	7.06e-01	8.15e-01	3.65e-02	3.08e-01	7.53e-01	8.59e-01	4.29e-01
REACTOME MAP KINASE ACTIVATION IN TLR CASCADE	43	4.31e-01	5.96e-01	0.248	0.121000	-0.06920	-0.118000	5.04e-03	-1.76e-02	-0.140000	0.062900	6.42e-02	2.10e-01	4.94e-01	1.30e-01	7.51e-01	9.88e-01	1.74e-01	4.56e-01	4.69e-01
REACTOME TOLL RECEPTOR CASCADES	79	1.17e-01	2.79e-01	0.248	-0.064100	-0.01310	-0.167000	9.70e-02	-1.09e-01	-0.078200	0.026400	2.96e-02	3.40e-01	8.49e-01	9.65e-03	1.12e-01	1.14e-01	3.56e-01	6.88e-01	5.65e-01
REACTOME LATE PHASE OF HIV LIFE CYCLE	86	2.49e-01	4.35e-01	0.247	-0.104000	0.12800	0.042600	8.01e-02	-2.00e-03	0.140000	0.069800	3.26e-02	3.95e-02	6.45e-02	7.18e-01	2.37e-01	7.10e-01	4.87e-02	3.22e-01	4.86e-01
REACTOME DNA REPLICATION	111	3.62e-02	1.19e-01	0.247	0.046700	0.15900	-0.002100	-6.61e-03	-2.13e-02	0.154000	0.082400	-4.66e-02	3.35e-01	1.76e-02	9.12e-01	8.71e-01	7.44e-01	9.41e-03	6.91e-02	5.30e-01
REACTOME TRAF6 MEDIATED INDUCTION OF NFKB AND MAP KINASES UPON TLR7 8 OR 9 ACTIVATION	58	1.84e-01	3.68e-01	0.247	0.051600	-0.05940	-0.149000	2.79e-02	-2.27e-02	-0.143000	0.081100	6.51e-02	6.22e-01	5.91e-01	3.10e-02	6.51e-01	8.18e-01	1.22e-01	2.74e-01	3.99e-01
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION	196	4.58e-06	3.99e-05	0.246	0.078600	0.09430	0.036600	-2.67e-02	3.69e-02	0.183000	0.072100	-5.98e-02	1.47e-01	2.42e-02	2.72e-01	5.65e-01	4.89e-01	1.32e-06	9.46e-02	1.65e-01
REACTOME DARPP 32 EVENTS	18	7.22e-01	8.03e-01	0.246	0.157000	-0.04850	0.033200	5.52e-02	-9.91e-03	-0.073500	0.091700	-1.24e-01	4.67e-01	7.05e-01	8.33e-01	4.77e-01	7.38e-01	7.45e-01	3.50e-01	3.29e-01
REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS	17	7.70e-01	8.32e-01	0.245	0.064200	-0.03790	0.047600	-1.19e-01	-1.62e-01	-0.053700	0.059500	-7.24e-02	5.59e-01	7.72e-01	8.53e-01	3.44e-01	3.37e-01	6.30e-01	4.69e-01	6.28e-01
REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	17	7.70e-01	8.32e-01	0.245	0.064200	-0.03790	0.047600	-1.19e-01	-1.62e-01	-0.053700	0.059500	-7.24e-02	5.59e-01	7.72e-01	8.53e-01	3.44e-01	3.37e-01	6.30e-01	4.69e-01	6.28e-01
REACTOME NFKB AND MAP KINASES ACTIVATION MEDIATED BY TLR4 SIGNALING REPERTOIRE	54	2.08e-01	4.00e-01	0.244	0.040600	-0.04790	-0.142000	-9.28e-03	-3.35e-02	-0.126000	0.113000	7.60e-02	6.40e-01	7.41e-01	7.02e-02	9.05e-01	7.76e-01	1.34e-01	1.46e-01	2.39e-01
REACTOME CELL CYCLE	220	1.05e-03	6.09e-03	0.244	-0.031000	0.13300	0.042500	2.55e-02	-5.87e-02	0.130000	0.097700	-9.16e-02	3.35e-01	3.10e-03	1.88e-01	4.78e-01	8.30e-02	9.99e-04	7.91e-03	2.04e-02
REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	10	9.70e-01	9.81e-01	0.244	-0.051900	-0.02170	0.106000	-5.73e-02	-1.57e-01	0.111000	0.057900	3.40e-02	3.88e-01	8.98e-01	9.55e-01	8.47e-01	4.24e-01	4.83e-01	8.57e-01	8.97e-01
REACTOME GAB1 SIGNALOSOME	33	5.99e-01	7.29e-01	0.243	-0.166000	-0.15400	-0.009560	-2.90e-02	1.47e-02	-0.001620	0.012300	8.30e-02	1.73e-01	1.05e-01	9.38e-01	7.21e-01	5.65e-01	9.32e-01	8.35e-01	2.92e-01
REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	21	8.03e-01	8.46e-01	0.241	0.093300	-0.12700	0.125000	9.57e-02	1.46e-02	-0.063100	0.016900	6.35e-02	5.90e-01	2.81e-01	3.20e-01	4.08e-01	9.66e-01	5.60e-01	8.97e-01	6.22e-01
REACTOME UNFOLDED PROTEIN RESPONSE	64	9.87e-02	2.47e-01	0.240	-0.057000	-0.12600	0.021000	7.67e-02	-8.76e-02	-0.053800	-0.033900	1.43e-01	1.88e-01	1.03e-01	7.14e-01	1.96e-01	2.22e-01	5.22e-01	6.03e-01	7.56e-02
REACTOME CA DEPENDENT EVENTS	14	9.34e-01	9.62e-01	0.240	-0.136000	-0.10400	0.133000	-2.72e-03	-3.00e-02	0.005720	0.003680	-9.88e-02	5.40e-01	2.75e-01	4.03e-01	7.62e-01	9.01e-01	8.68e-01	7.86e-01	7.05e-01
REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	16	8.10e-01	8.52e-01	0.237	0.125000	-0.04790	0.027200	-1.27e-01	-1.13e-01	-0.077000	0.046800	-2.19e-02	3.03e-01	7.25e-01	9.86e-01	3.24e-01	5.81e-01	5.19e-01	5.30e-01	9.36e-01
REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE	61	2.48e-01	4.35e-01	0.237	0.046000	-0.05150	-0.143000	3.77e-02	-3.71e-02	-0.141000	0.077000	4.72e-02	6.59e-01	6.61e-01	5.20e-02	5.53e-01	6.60e-01	1.21e-01	2.95e-01	5.49e-01
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM	166	1.16e-01	2.79e-01	0.236	-0.113000	0.11400	-0.007410	6.92e-02	-1.19e-01	0.057200	0.058200	-6.28e-02	8.39e-02	1.31e-02	6.57e-01	2.00e-01	4.96e-02	5.57e-02	1.80e-01	2.30e-01
REACTOME SIGNALING BY FGFR MUTANTS	28	6.89e-01	7.81e-01	0.234	-0.152000	0.00595	-0.110000	4.06e-02	-7.20e-02	-0.063500	-0.072200	-5.83e-02	8.89e-02	9.14e-01	1.57e-01	8.79e-01	5.05e-01	7.78e-01	6.74e-01	7.07e-01
REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	13	9.89e-01	9.92e-01	0.232	-0.025000	-0.06550	-0.140000	-1.59e-01	3.54e-02	-0.014900	0.050600	1.81e-02	7.58e-01	8.41e-01	2.85e-01	5.42e-01	9.67e-01	8.85e-01	9.63e-01	9.33e-01
REACTOME SIGNALING BY SCF KIT	61	2.62e-01	4.46e-01	0.230	-0.117000	-0.02420	-0.107000	-4.49e-02	-6.43e-02	-0.051300	0.127000	4.69e-02	2.04e-01	6.14e-01	1.28e-01	5.76e-01	6.34e-01	3.55e-01	1.41e-01	5.65e-01
REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	13	7.87e-01	8.40e-01	0.229	-0.125000	-0.08290	0.011900	-1.18e-02	2.90e-02	-0.152000	0.002400	-7.53e-02	3.09e-01	2.66e-01	7.88e-01	6.48e-01	7.85e-01	2.19e-01	9.61e-01	6.26e-01
REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	57	4.86e-01	6.41e-01	0.228	-0.060000	-0.01360	0.005020	4.16e-02	-1.29e-01	-0.156000	0.066700	3.31e-02	5.98e-01	9.32e-01	7.92e-01	5.70e-01	4.92e-02	1.46e-01	3.33e-01	6.00e-01
REACTOME SIGNALING BY FGFR1 MUTANTS	21	8.44e-01	8.83e-01	0.225	-0.143000	-0.00482	-0.061300	4.33e-02	-1.41e-01	-0.065900	-0.010900	-1.35e-02	1.25e-01	8.20e-01	3.53e-01	7.10e-01	1.91e-01	7.31e-01	9.23e-01	9.16e-01
REACTOME PI3K EVENTS IN ERBB2 SIGNALING	32	6.45e-01	7.54e-01	0.223	-0.089500	-0.12500	0.035400	-1.77e-02	5.65e-02	-0.025100	0.051000	1.34e-01	2.50e-01	1.90e-01	7.55e-01	8.86e-01	7.13e-01	7.43e-01	6.15e-01	1.80e-01
REACTOME DIABETES PATHWAYS	92	8.34e-02	2.26e-01	0.223	-0.095800	-0.06480	-0.030400	1.06e-01	-1.30e-01	-0.029300	-0.014300	7.76e-02	7.47e-02	2.57e-01	5.73e-01	4.00e-02	4.23e-02	7.17e-01	9.06e-01	2.06e-01
REACTOME METABOLISM OF CARBOHYDRATES	137	1.77e-03	9.60e-03	0.223	0.042100	0.09940	0.066800	1.47e-01	5.14e-02	0.086600	-0.020200	3.60e-02	3.35e-01	2.96e-02	9.24e-02	3.47e-03	1.64e-01	4.34e-02	5.26e-01	3.81e-01
REACTOME SIGNAL TRANSDUCTION BY L1	28	7.35e-01	8.13e-01	0.219	-0.066800	-0.01760	-0.080400	1.25e-01	-6.54e-02	-0.091200	0.025000	8.94e-02	5.16e-01	8.54e-01	3.44e-01	2.24e-01	6.18e-01	3.32e-01	6.55e-01	3.54e-01
REACTOME L1CAM INTERACTIONS	52	3.30e-01	5.10e-01	0.219	-0.061600	-0.04110	0.000671	8.72e-02	-6.24e-02	-0.108000	-0.005110	1.38e-01	4.32e-01	5.81e-01	8.90e-01	2.47e-01	4.13e-01	1.30e-01	9.36e-01	6.77e-02
REACTOME SIGNALING BY ILS	72	6.31e-01	7.48e-01	0.218	-0.109000	0.02710	-0.022700	2.70e-02	-1.34e-01	-0.024600	0.107000	-5.96e-02	1.59e-01	6.04e-01	6.62e-01	9.57e-01	1.51e-01	9.32e-01	1.60e-01	3.57e-01
REACTOME TRIGLYCERIDE BIOSYNTHESIS	25	1.39e-01	3.12e-01	0.215	0.047100	-0.00500	-0.088800	1.13e-02	-9.32e-02	0.114000	0.088600	-7.96e-02	1.77e-01	9.03e-01	4.39e-01	9.03e-01	8.66e-01	1.35e-01	7.65e-01	5.17e-01
REACTOME SIGNALING BY THE B CELL RECEPTOR BCR	104	7.47e-02	2.07e-01	0.212	-0.053400	0.01850	-0.027500	-3.25e-02	-1.25e-02	0.157000	0.122000	-2.31e-02	9.31e-01	8.52e-01	5.70e-01	5.05e-01	5.45e-01	9.55e-03	2.83e-02	7.41e-01
REACTOME TRANSMEMBRANE TRANSPORT OF SMALL MOLECULES	179	3.93e-03	1.91e-02	0.212	0.067300	-0.07200	0.025800	-3.29e-02	5.26e-02	-0.135000	0.001120	1.13e-01	2.14e-01	4.38e-02	8.63e-01	4.13e-01	3.62e-01	5.93e-04	7.44e-01	4.63e-03
REACTOME PYRIMIDINE METABOLISM	10	9.93e-01	9.93e-01	0.210	0.081800	-0.00649	-0.074100	-2.32e-02	9.83e-02	0.007290	-0.080800	-1.24e-01	7.58e-01	9.62e-01	6.49e-01	9.11e-01	6.59e-01	9.98e-01	6.44e-01	4.56e-01
REACTOME SIGNALING BY PDGF	87	1.81e-01	3.65e-01	0.207	-0.084000	0.06060	-0.055900	1.28e-01	-9.52e-02	-0.023800	-0.028500	4.91e-02	1.50e-01	3.95e-01	3.04e-01	1.89e-02	1.56e-01	4.75e-01	4.77e-01	3.73e-01
REACTOME PI3K CASCADE	47	5.47e-01	6.92e-01	0.202	0.094500	-0.03880	0.004080	8.08e-02	6.91e-02	0.059000	0.013500	1.25e-01	3.96e-01	7.07e-01	7.95e-01	4.01e-01	5.62e-01	3.10e-01	8.03e-01	9.68e-02
REACTOME OPIOID SIGNALLING	41	5.72e-01	7.11e-01	0.202	-0.099300	-0.07780	0.009170	-9.27e-02	1.04e-02	-0.099700	0.036500	-6.83e-02	2.81e-01	2.63e-01	9.63e-01	4.77e-01	7.13e-01	2.54e-01	8.16e-01	5.24e-01
REACTOME NEURONAL SYSTEM	90	1.78e-01	3.65e-01	0.201	0.034500	-0.03710	0.025000	-6.05e-02	-5.50e-02	-0.155000	-0.077800	-2.35e-02	5.08e-01	4.38e-01	6.21e-01	3.27e-01	4.99e-01	2.69e-03	1.73e-01	6.48e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR	63	3.53e-01	5.34e-01	0.198	-0.130000	-0.09010	0.063300	1.89e-02	-2.00e-02	-0.071400	0.066900	3.56e-03	6.04e-02	1.70e-01	5.31e-01	7.74e-01	7.93e-01	3.68e-01	4.44e-01	7.64e-01
REACTOME IL1 SIGNALING	27	9.54e-01	9.72e-01	0.196	-0.010600	0.04270	0.054500	8.37e-02	-5.20e-02	-0.021600	0.117000	-9.83e-02	5.40e-01	3.97e-01	6.97e-01	3.96e-01	5.39e-01	6.39e-01	4.09e-01	3.64e-01
REACTOME INTEGRATION OF ENERGY METABOLISM	63	6.62e-01	7.63e-01	0.194	-0.127000	-0.08960	-0.044700	-2.27e-02	-8.56e-02	-0.056100	0.023300	-6.58e-03	1.33e-01	1.24e-01	4.92e-01	8.12e-01	4.03e-01	5.29e-01	1.00e+00	8.64e-01
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES	65	4.59e-01	6.20e-01	0.194	-0.026600	-0.04540	0.005710	-6.24e-02	-8.18e-02	-0.133000	-0.054700	-5.94e-02	7.87e-01	4.12e-01	8.51e-01	4.53e-01	3.36e-01	2.01e-02	3.58e-01	4.72e-01
REACTOME INSULIN SYNTHESIS AND PROCESSING	13	9.90e-01	9.92e-01	0.193	-0.082700	-0.09680	-0.072200	-2.22e-03	4.71e-02	0.049500	0.077500	7.14e-02	4.90e-01	5.17e-01	6.13e-01	9.92e-01	8.61e-01	7.79e-01	6.23e-01	6.60e-01
REACTOME DEADENYLATION DEPENDENT MRNA DECAY	39	7.10e-01	7.92e-01	0.190	-0.022800	-0.08510	0.115000	-4.97e-02	1.50e-02	0.058200	0.070700	-6.43e-02	4.53e-01	2.00e-01	4.16e-01	6.23e-01	9.06e-01	5.57e-01	5.84e-01	4.20e-01
REACTOME APOPTOSIS	102	1.37e-01	3.11e-01	0.186	0.007780	0.10500	0.002920	8.91e-03	-2.49e-02	0.150000	0.011200	-1.69e-02	6.33e-01	2.61e-02	8.57e-01	8.77e-01	7.35e-01	5.91e-03	5.67e-01	9.58e-01
REACTOME PI METABOLISM	38	6.56e-01	7.63e-01	0.185	-0.094300	-0.10900	0.066200	-1.60e-02	-2.86e-02	0.054600	0.028700	6.47e-02	3.01e-01	2.19e-01	3.52e-01	8.24e-01	7.66e-01	5.98e-01	8.71e-01	5.04e-01
REACTOME GENERIC TRANSCRIPTION PATHWAY	139	2.36e-01	4.21e-01	0.183	0.078400	-0.02010	0.012800	1.35e-01	-3.41e-02	-0.070300	0.012100	4.54e-02	5.75e-01	8.25e-01	8.61e-01	9.23e-03	4.24e-01	3.05e-01	6.27e-01	3.56e-01
REACTOME NEUROTRANSMITTER RECEPTOR BINDING AND DOWNSTREAM TRANSMISSION IN THE POSTSYNAPTIC CELL	52	7.77e-01	8.35e-01	0.179	-0.030600	0.04040	-0.023000	-6.16e-02	-8.67e-02	-0.074500	-0.040200	-1.02e-01	8.55e-01	7.18e-01	8.62e-01	5.24e-01	4.16e-01	1.80e-01	5.09e-01	2.37e-01
REACTOME SIGNALING BY ERBB4	67	4.56e-01	6.17e-01	0.176	-0.016600	-0.03480	0.061900	-5.18e-02	-5.73e-02	-0.043600	0.124000	4.78e-02	5.82e-01	5.88e-01	4.03e-01	5.56e-01	2.30e-01	5.59e-01	7.51e-02	5.23e-01
REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	10	9.71e-01	9.81e-01	0.176	0.025000	-0.02610	-0.012000	-6.49e-02	-1.05e-01	0.072500	0.094700	3.50e-04	9.94e-01	8.72e-01	9.22e-01	7.25e-01	4.84e-01	7.05e-01	5.98e-01	9.79e-01
REACTOME METABOLISM OF NUCLEOTIDES	49	5.14e-01	6.68e-01	0.175	-0.036600	0.01590	0.060900	-9.91e-02	-2.78e-03	0.085400	0.030400	8.51e-02	6.42e-01	4.93e-01	5.72e-01	2.40e-01	9.21e-01	1.46e-01	6.12e-01	2.23e-01
REACTOME IMMUNE SYSTEM	557	5.53e-04	3.43e-03	0.173	-0.081300	0.06890	-0.015300	4.83e-02	-7.64e-02	0.091200	0.033200	-2.81e-02	2.51e-02	6.50e-03	5.64e-01	4.87e-02	3.59e-02	3.14e-05	2.05e-01	3.58e-01
REACTOME SIGNALING BY FGFR	72	3.96e-01	5.67e-01	0.169	-0.115000	-0.07140	0.009310	1.80e-02	-2.05e-02	-0.085400	0.044300	3.75e-04	6.77e-02	2.41e-01	9.00e-01	7.65e-01	7.42e-01	2.26e-01	6.26e-01	8.19e-01
REACTOME ADAPTIVE IMMUNE SYSTEM	360	1.02e-02	4.15e-02	0.168	-0.075700	0.05690	-0.000689	1.27e-02	-4.81e-02	0.116000	0.014500	-5.50e-02	7.85e-02	7.64e-02	8.77e-01	7.21e-01	4.73e-01	7.30e-05	6.96e-01	9.66e-02
REACTOME PI3K AKT ACTIVATION	31	9.57e-01	9.73e-01	0.165	-0.006040	-0.08110	-0.022700	-3.58e-02	5.04e-02	-0.061300	-0.004090	1.13e-01	7.51e-01	4.01e-01	7.79e-01	7.45e-01	7.63e-01	4.91e-01	9.59e-01	2.72e-01
REACTOME SIGNALING BY EGFR IN CANCER	85	6.62e-01	7.63e-01	0.165	-0.138000	-0.00506	-0.003190	6.09e-02	-5.29e-02	-0.000693	0.038500	-1.11e-02	5.36e-02	8.02e-01	9.95e-01	2.54e-01	6.53e-01	8.50e-01	6.56e-01	9.85e-01
REACTOME METABOLISM OF LIPIDS AND LIPOPROTEINS	289	7.35e-03	3.30e-02	0.157	-0.002060	-0.11500	-0.014400	-1.42e-02	5.71e-02	-0.007820	-0.084400	2.06e-02	9.30e-01	4.47e-04	7.50e-01	7.73e-01	8.36e-02	9.58e-01	7.11e-03	4.47e-01
REACTOME SIGNALING BY INSULIN RECEPTOR	75	6.36e-01	7.48e-01	0.156	0.062900	-0.00447	-0.037600	5.55e-02	3.94e-02	0.039200	0.071800	8.64e-02	5.71e-01	9.99e-01	3.91e-01	4.44e-01	7.79e-01	4.28e-01	2.37e-01	1.56e-01
REACTOME SIGNALLING BY NGF	160	2.81e-01	4.61e-01	0.151	-0.030200	-0.00918	-0.026900	6.84e-02	-7.94e-02	-0.094900	0.017100	2.92e-02	6.58e-01	7.79e-01	5.38e-01	9.33e-02	7.53e-02	5.49e-02	7.43e-01	4.33e-01
REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	72	5.71e-01	7.11e-01	0.151	-0.089700	-0.03810	0.008280	-1.98e-02	-5.49e-02	-0.094700	0.020300	-2.05e-02	1.84e-01	4.44e-01	9.61e-01	9.05e-01	4.63e-01	1.03e-01	9.67e-01	8.11e-01
REACTOME SIGNALING BY FGFR IN DISEASE	85	5.31e-01	6.82e-01	0.150	-0.110000	-0.02320	0.005820	2.64e-02	-4.84e-02	-0.070000	0.036600	-2.30e-02	6.92e-02	5.19e-01	8.71e-01	6.40e-01	4.69e-01	2.62e-01	6.73e-01	8.48e-01
REACTOME PHOSPHOLIPID METABOLISM	122	2.71e-01	4.53e-01	0.148	-0.052900	-0.12900	0.025700	-1.61e-02	2.48e-02	0.030700	-0.005550	-6.10e-03	5.00e-01	1.36e-02	5.08e-01	6.76e-01	6.08e-01	5.65e-01	7.55e-01	9.07e-01
REACTOME MITOTIC PROMETAPHASE	46	9.87e-01	9.92e-01	0.146	-0.009500	0.08810	-0.024200	4.58e-04	-4.84e-02	-0.051200	0.031300	-8.28e-02	9.36e-01	6.88e-01	9.48e-01	9.80e-01	6.57e-01	5.42e-01	7.35e-01	4.16e-01
REACTOME SIGNALING BY ERBB2	69	7.85e-01	8.40e-01	0.137	-0.055100	-0.04180	0.063600	2.21e-02	-2.94e-02	-0.057200	0.070400	1.68e-02	4.39e-01	4.17e-01	3.86e-01	6.04e-01	7.47e-01	3.01e-01	4.35e-01	7.33e-01
REACTOME INSULIN RECEPTOR SIGNALLING CASCADE	61	7.67e-01	8.32e-01	0.134	0.079500	-0.00295	-0.017800	7.79e-02	5.24e-03	0.017900	0.051100	4.92e-02	4.55e-01	9.67e-01	5.91e-01	3.32e-01	8.22e-01	6.38e-01	4.28e-01	4.37e-01
REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	103	7.45e-01	8.16e-01	0.117	-0.025500	-0.02140	-0.028700	6.38e-02	-5.12e-02	-0.064500	0.011900	2.67e-02	6.98e-01	5.82e-01	5.02e-01	1.85e-01	4.33e-01	1.69e-01	9.22e-01	5.60e-01

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Detailed Gene set reports

REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING

REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING

metric	value
setSize	12
pMANOVA	4.51e-16
p.adjustMANOVA	1.25e-14
s.dist	1.7
s.de1	0.823
s.de2	-0.0381
s.de3	0.53
s.de4	-0.913
s.de5	0.806
s.de6	0.121
s.de7	-0.664
s.de8	-0.0661
p.de1	1.24e-06
p.de2	0.801
p.de3	0.00095
p.de4	9.82e-09
p.de5	1.29e-06
p.de6	0.473
p.de7	3.9e-05
p.de8	0.652

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

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Top 20 genes

Gene	d4	d1
Atp5k	-4469	4932
Atp5h	-4478	4750
Atp5l	-4479	4715
Atp5c1	-4262	4840
Atp5j2	-4497	4561
Atp5j	-4493	4083
Atp5b	-4394	4068
Atp5g1	-4473	3957
Atp5e	-4298	3770
Atp5d	-3723	4021
Atp5a1	-4397	2948
Atp5o	-4444	2413

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Atp5a1	2948	945	4622	-4397	4414	3997	-3481	-323
Atp5b	4068	766	4308	-4394	4364	2977	-3385	77
Atp5c1	4840	-1751	-1307	-4262	4010	870	-3312	2861
Atp5d	4021	1286	4139	-3723	3861	1299	-1770	-1661
Atp5e	3770	-1998	4342	-4298	1823	-1601	-1827	-594
Atp5g1	3957	-451	4036	-4473	3398	-1812	-4242	975
Atp5h	4750	-2458	1887	-4478	4284	-1072	-1945	-1235
Atp5j	4083	571	3287	-4493	4211	2688	-3732	-1698
Atp5j2	4561	-152	1939	-4497	4025	2353	-4165	-2914
Atp5k	4932	3024	3909	-4469	3371	-4116	-3534	-424
Atp5l	4715	-580	-3195	-4479	3250	-865	-3557	-113
Atp5o	2413	-1474	2992	-4444	4088	1962	-2923	995

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REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE

REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE

metric	value
setSize	19
pMANOVA	8.66e-25
p.adjustMANOVA	3.4e-23
s.dist	1.61
s.de1	0.569
s.de2	-0.364
s.de3	0.375
s.de4	-0.86
s.de5	0.789
s.de6	0.209
s.de7	-0.762
s.de8	0.146
p.de1	3.3e-05
p.de2	0.00372
p.de3	0.00345
p.de4	1.14e-11
p.de5	2.59e-09
p.de6	0.108
p.de7	2.97e-09
p.de8	0.26

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).
Removed 2867 rows containing non-finite values (stat_boxplot).

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Top 20 genes

Gene	d4	d5
Idh3b	-4476	4405
Dld	-4362	4466
Sdha	-4439	4325
Sdhb	-4523	4244
Fh1	-4295	4343
Aco2	-4261	4261
Idh2	-4555	3931
Idh3a	-4319	4144
Sucla2	-4157	4242
Mdh2	-4216	3980
Idh3g	-4113	3653
Dlst	-3926	3815
Sdhd	-3671	4033
Sdhc	-4432	3246
Ogdh	-3440	4008
Suclg2	-3785	3545
Cs	-4002	2868
Nnt	-3978	1178
Suclg1	-3000	1056

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Aco2	4062	553	4619	-4261	4261	1450	-1696	1944
Cs	1875	-3152	4451	-4002	2868	591	-3469	-819
Dld	4144	-601	-1398	-4362	4466	3847	-3015	2744
Dlst	3103	-355	4283	-3926	3815	-302	-3229	1620
Fh1	3656	-1024	885	-4295	4343	3201	-3781	2780
Idh2	2111	-4364	-4509	-4555	3931	-1689	-4496	-343
Idh3a	3768	-2535	3175	-4319	4144	2909	-3324	506
Idh3b	3245	-2354	1776	-4476	4405	3574	-3482	2625
Idh3g	2704	-1177	4584	-4113	3653	-495	-3626	170
Mdh2	3964	-1814	4548	-4216	3980	-551	-4127	-1788
Nnt	-2358	-4629	-4357	-3978	1178	27	-4352	792
Ogdh	2648	-3481	1940	-3440	4008	-13	-3477	2600
Sdha	2192	-1566	4157	-4439	4325	3442	-3882	-288
Sdhb	4623	-4252	-3127	-4523	4244	-2808	-4466	1549
Sdhc	2779	-550	3305	-4432	3246	291	-3674	-765
Sdhd	4666	1252	3409	-3671	4033	-1412	-3835	6
Sucla2	4024	-1059	1080	-4157	4242	2517	-3616	1946
Suclg1	420	-2186	2740	-3000	1056	1438	-3949	1036
Suclg2	2567	-320	3069	-3785	3545	2729	-3395	-3209

---

---

REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION

REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION

metric	value
setSize	13
pMANOVA	1.04e-13
p.adjustMANOVA	2.44e-12
s.dist	1.56
s.de1	0.532
s.de2	-0.619
s.de3	0.281
s.de4	-0.71
s.de5	0.813
s.de6	0.183
s.de7	-0.654
s.de8	0.246
p.de1	0.00137
p.de2	4.56e-05
p.de3	0.0712
p.de4	3.6e-06
p.de5	3.82e-07
p.de6	0.248
p.de7	2.51e-05
p.de8	0.111

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).
Removed 2867 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d5	d4
Hadhb	4518	-4520
Acadvl	4493	-4487
Acadl	4426	-4539
Acadm	4442	-4489
Hadha	4373	-4495
Eci1	4303	-4477
Decr1	4372	-4370
Hadh	4206	-4507
Echs1	4085	-4289
Mcee	4409	-3800
Acads	2490	-613
Pcca	1453	-30

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Acadl	4045	-4342	3368	-4539	4426	440	-3914	3230
Acadm	4505	-2703	196	-4489	4442	396	-4437	229
Acads	-1967	2063	4175	-613	2490	470	-3838	831
Acadvl	4088	-4156	804	-4487	4493	58	-4469	2906
Decr1	4455	-3636	-2357	-4370	4372	1892	-4324	1133
Echs1	1867	-4405	784	-4289	4085	155	-69	1814
Eci1	4518	-4349	-4580	-4477	4303	-3600	-4519	1069
Hadh	4453	-2501	3444	-4507	4206	3863	-4261	-2970
Hadha	3172	-3980	3926	-4495	4373	886	-3753	1554
Hadhb	986	-4160	-84	-4520	4518	4090	-4449	1786
Mcee	4235	-3534	-250	-3800	4409	-1857	-2055	422
Pcca	-8	-2725	4471	-30	1453	912	-2900	3775
Pccb	425	-698	3881	672	1669	3458	2620	-497

---

---

REACTOME_RESPIRATORY_ELECTRON_TRANSPORT

REACTOME_RESPIRATORY_ELECTRON_TRANSPORT

metric	value
setSize	59
pMANOVA	2.97e-61
p.adjustMANOVA	4.66e-59
s.dist	1.44
s.de1	0.643
s.de2	-0.0432
s.de3	0.115
s.de4	-0.843
s.de5	0.692
s.de6	0.0772
s.de7	-0.671
s.de8	0.0386
p.de1	9.05e-17
p.de2	0.529
p.de3	0.128
p.de4	7.79e-32
p.de5	5.23e-20
p.de6	0.327
p.de7	3.38e-20
p.de8	0.635

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).
Removed 2867 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d4	d5
Uqcrc2	-4471	4482
Ndufs1	-4348	4565
Ndufa5	-4395	4443
Ndufv2	-4459	4377
Etfdh	-4512	4263
Ndufa9	-4441	4330
Sdha	-4439	4325
Sdhb	-4523	4244
Ndufb9	-4427	4175
Etfa	-4481	4091
Ndufv1	-4280	4234
Uqcrfs1	-4440	4029
Etfb	-4324	4063
Cox6c	-4446	3868
Ndufa8	-4084	4120
Ndufs3	-4290	3921
Ndufa4	-4465	3701
Ndufb3	-4343	3772
Ndufb5	-4092	3907
Cycs	-4041	3952

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Cox4i1	-1175	-4574	3610	-4414	3135	-1841	-3989	-612
Cox5a	1611	-1040	1373	-4430	2941	693	-3123	-253
Cox6a1	-1102	2088	-4499	-917	2193	3280	3324	3370
Cox6b1	4258	-2177	4166	-4323	3494	-128	-3942	255
Cox6c	4900	-2595	-4506	-4446	3868	-1364	-4172	2898
Cox7a2l	-626	2428	-2561	1651	3214	4329	-2731	-164
Cox7c	4806	2047	-2646	-4398	3166	389	-3892	-1664
Cox8a	-4207	-585	-4455	-4185	1126	1339	2260	-2154
Cyc1	1503	2753	1310	-4346	3347	1327	-4119	-22
Cycs	4767	-846	-4409	-4041	3952	1621	-4276	2963
Etfa	4161	-3825	-3087	-4481	4091	-929	-4065	2431
Etfb	4620	-3428	-1109	-4324	4063	297	-4081	-762
Etfdh	4870	-4299	-2693	-4512	4263	-2453	-4046	2376
Ndufa1	3432	-383	3376	-4387	1952	-1331	-2840	-2147
Ndufa10	3925	-334	3385	-4073	3377	270	-2791	785
Ndufa11	2993	-41	1113	-4258	3620	-882	-4279	-1778
Ndufa12	3940	2800	-1158	-4312	3655	2183	104	1370
Ndufa13	1127	3860	4429	-3474	2566	3228	-2027	-3286
Ndufa2	4548	518	-1035	-4114	1960	-2646	-3184	2364
Ndufa3	-279	-3509	2228	-4275	-397	-2891	-3544	757
Ndufa4	4834	452	-4309	-4465	3701	-1399	-3393	1433
Ndufa5	4837	-2935	-4349	-4395	4443	13	-3958	1270
Ndufa6	4218	1447	-1298	-4382	3157	1678	-3467	940
Ndufa7	3722	1224	4336	-3212	1849	1076	-888	-1835
Ndufa8	2434	-3720	3987	-4084	4120	-3630	-3263	419
Ndufa9	3718	1825	2947	-4441	4330	3751	-4049	1594
Ndufab1	3293	-299	-2206	-4496	2624	-1602	-3559	1851
Ndufb10	3495	-670	1622	-4247	2990	-3372	-3824	2964
Ndufb2	4542	2377	-504	-4162	1707	1114	-3398	3788
Ndufb3	2969	1263	-1172	-4343	3772	-249	-4478	319
Ndufb4	4117	621	-3319	-3792	585	559	-3382	1548
Ndufb5	4492	-753	609	-4092	3907	1235	-3974	3218
Ndufb6	-546	1726	4296	-2521	2877	1543	-3764	-1925
Ndufb7	3371	-1622	-2094	-3405	4451	-655	-3896	-2687
Ndufb9	4636	210	-1144	-4427	4175	-1016	-3434	-593
Ndufc1	2311	-138	-210	-3543	1624	-3057	-3387	-137
Ndufc2	4412	3377	-831	-3536	3116	2944	-1475	-850
Ndufs1	4521	-807	3129	-4348	4565	4277	-4268	2066
Ndufs2	3034	983	4195	-4254	3039	1660	-1673	2225
Ndufs3	2939	1072	4241	-4290	3921	2762	-1745	-1440
Ndufs4	4549	695	2262	-4228	2802	-10	-4120	-742
Ndufs5	4431	-837	1012	-3731	3668	-369	-2953	-2022
Ndufs6	4588	2591	3034	-3168	3543	1758	-4212	-1251
Ndufs7	2274	-462	2640	-4037	1436	-1678	-2420	-2863
Ndufs8	2152	-54	1185	-4340	3565	2046	-3720	3192
Ndufv1	3108	-1107	1305	-4280	4234	87	-4471	-3189
Ndufv2	4042	-2284	-3030	-4459	4377	3544	-2872	1644
Ndufv3	2259	1048	4042	-3906	164	-3497	36	-2705
Sdha	2192	-1566	4157	-4439	4325	3442	-3882	-288
Sdhb	4623	-4252	-3127	-4523	4244	-2808	-4466	1549
Sdhc	2779	-550	3305	-4432	3246	291	-3674	-765
Sdhd	4666	1252	3409	-3671	4033	-1412	-3835	6
Uqcr11	3467	-1012	4207	-4449	3297	-1037	-2282	-3852
Uqcrb	4203	1643	-306	-4338	3284	3290	-3668	-35
Uqcrc1	4032	2125	3722	-4269	2203	-1682	-4293	-1080
Uqcrc2	2858	-3601	2012	-4471	4482	3812	-3908	1703
Uqcrfs1	4443	792	2619	-4440	4029	2622	-4115	-237
Uqcrh	4460	364	78	-4287	3436	1889	-3148	-973
Uqcrq	4294	-1862	-317	-4425	2925	-2147	-4424	1023

---

---

REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_

REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_

metric	value
setSize	73
pMANOVA	3.66e-75
p.adjustMANOVA	8.63e-73
s.dist	1.42
s.de1	0.649
s.de2	-0.0356
s.de3	0.182
s.de4	-0.822
s.de5	0.697
s.de6	0.103
s.de7	-0.628
s.de8	0.023
p.de1	1e-20
p.de2	0.561
p.de3	0.00626
p.de4	3.96e-37
p.de5	1.02e-24
p.de6	0.135
p.de7	9.47e-22
p.de8	0.777

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).
Removed 2867 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d4	d5
Uqcrc2	-4471	4482
Ndufs1	-4348	4565
Ndufa5	-4395	4443
Ndufv2	-4459	4377
Atp5a1	-4397	4414
Etfdh	-4512	4263
Ndufa9	-4441	4330
Sdha	-4439	4325
Sdhb	-4523	4244
Atp5h	-4478	4284
Atp5b	-4394	4364
Atp5j	-4493	4211
Ndufb9	-4427	4175
Etfa	-4481	4091
Atp5o	-4444	4088
Ndufv1	-4280	4234
Atp5j2	-4497	4025
Uqcrfs1	-4440	4029
Etfb	-4324	4063
Cox6c	-4446	3868

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Atp5a1	2948	945	4622	-4397	4414	3997	-3481	-323
Atp5b	4068	766	4308	-4394	4364	2977	-3385	77
Atp5c1	4840	-1751	-1307	-4262	4010	870	-3312	2861
Atp5d	4021	1286	4139	-3723	3861	1299	-1770	-1661
Atp5e	3770	-1998	4342	-4298	1823	-1601	-1827	-594
Atp5g1	3957	-451	4036	-4473	3398	-1812	-4242	975
Atp5h	4750	-2458	1887	-4478	4284	-1072	-1945	-1235
Atp5j	4083	571	3287	-4493	4211	2688	-3732	-1698
Atp5j2	4561	-152	1939	-4497	4025	2353	-4165	-2914
Atp5k	4932	3024	3909	-4469	3371	-4116	-3534	-424
Atp5l	4715	-580	-3195	-4479	3250	-865	-3557	-113
Atp5o	2413	-1474	2992	-4444	4088	1962	-2923	995
Cox4i1	-1175	-4574	3610	-4414	3135	-1841	-3989	-612
Cox5a	1611	-1040	1373	-4430	2941	693	-3123	-253
Cox6a1	-1102	2088	-4499	-917	2193	3280	3324	3370
Cox6b1	4258	-2177	4166	-4323	3494	-128	-3942	255
Cox6c	4900	-2595	-4506	-4446	3868	-1364	-4172	2898
Cox7a2l	-626	2428	-2561	1651	3214	4329	-2731	-164
Cox7c	4806	2047	-2646	-4398	3166	389	-3892	-1664
Cox8a	-4207	-585	-4455	-4185	1126	1339	2260	-2154
Cyc1	1503	2753	1310	-4346	3347	1327	-4119	-22
Cycs	4767	-846	-4409	-4041	3952	1621	-4276	2963
Etfa	4161	-3825	-3087	-4481	4091	-929	-4065	2431
Etfb	4620	-3428	-1109	-4324	4063	297	-4081	-762
Etfdh	4870	-4299	-2693	-4512	4263	-2453	-4046	2376
Ndufa1	3432	-383	3376	-4387	1952	-1331	-2840	-2147
Ndufa10	3925	-334	3385	-4073	3377	270	-2791	785
Ndufa11	2993	-41	1113	-4258	3620	-882	-4279	-1778
Ndufa12	3940	2800	-1158	-4312	3655	2183	104	1370
Ndufa13	1127	3860	4429	-3474	2566	3228	-2027	-3286
Ndufa2	4548	518	-1035	-4114	1960	-2646	-3184	2364
Ndufa3	-279	-3509	2228	-4275	-397	-2891	-3544	757
Ndufa4	4834	452	-4309	-4465	3701	-1399	-3393	1433
Ndufa5	4837	-2935	-4349	-4395	4443	13	-3958	1270
Ndufa6	4218	1447	-1298	-4382	3157	1678	-3467	940
Ndufa7	3722	1224	4336	-3212	1849	1076	-888	-1835
Ndufa8	2434	-3720	3987	-4084	4120	-3630	-3263	419
Ndufa9	3718	1825	2947	-4441	4330	3751	-4049	1594
Ndufab1	3293	-299	-2206	-4496	2624	-1602	-3559	1851
Ndufb10	3495	-670	1622	-4247	2990	-3372	-3824	2964
Ndufb2	4542	2377	-504	-4162	1707	1114	-3398	3788
Ndufb3	2969	1263	-1172	-4343	3772	-249	-4478	319
Ndufb4	4117	621	-3319	-3792	585	559	-3382	1548
Ndufb5	4492	-753	609	-4092	3907	1235	-3974	3218
Ndufb6	-546	1726	4296	-2521	2877	1543	-3764	-1925
Ndufb7	3371	-1622	-2094	-3405	4451	-655	-3896	-2687
Ndufb9	4636	210	-1144	-4427	4175	-1016	-3434	-593
Ndufc1	2311	-138	-210	-3543	1624	-3057	-3387	-137
Ndufc2	4412	3377	-831	-3536	3116	2944	-1475	-850
Ndufs1	4521	-807	3129	-4348	4565	4277	-4268	2066
Ndufs2	3034	983	4195	-4254	3039	1660	-1673	2225
Ndufs3	2939	1072	4241	-4290	3921	2762	-1745	-1440
Ndufs4	4549	695	2262	-4228	2802	-10	-4120	-742
Ndufs5	4431	-837	1012	-3731	3668	-369	-2953	-2022
Ndufs6	4588	2591	3034	-3168	3543	1758	-4212	-1251
Ndufs7	2274	-462	2640	-4037	1436	-1678	-2420	-2863
Ndufs8	2152	-54	1185	-4340	3565	2046	-3720	3192
Ndufv1	3108	-1107	1305	-4280	4234	87	-4471	-3189
Ndufv2	4042	-2284	-3030	-4459	4377	3544	-2872	1644
Ndufv3	2259	1048	4042	-3906	164	-3497	36	-2705
Sdha	2192	-1566	4157	-4439	4325	3442	-3882	-288
Sdhb	4623	-4252	-3127	-4523	4244	-2808	-4466	1549
Sdhc	2779	-550	3305	-4432	3246	291	-3674	-765
Sdhd	4666	1252	3409	-3671	4033	-1412	-3835	6
Ucp2	-4690	2516	-2671	3195	-3703	2678	4272	-3047
Ucp3	2156	-513	3160	1016	4607	4595	4646	3946
Uqcr11	3467	-1012	4207	-4449	3297	-1037	-2282	-3852
Uqcrb	4203	1643	-306	-4338	3284	3290	-3668	-35
Uqcrc1	4032	2125	3722	-4269	2203	-1682	-4293	-1080
Uqcrc2	2858	-3601	2012	-4471	4482	3812	-3908	1703
Uqcrfs1	4443	792	2619	-4440	4029	2622	-4115	-237
Uqcrh	4460	364	78	-4287	3436	1889	-3148	-973
Uqcrq	4294	-1862	-317	-4425	2925	-2147	-4424	1023

---

---

REACTOME_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT

REACTOME_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT

metric	value
setSize	107
pMANOVA	6.02e-101
p.adjustMANOVA	2.84e-98
s.dist	1.36
s.de1	0.599
s.de2	-0.121
s.de3	0.195
s.de4	-0.788
s.de5	0.681
s.de6	0.15
s.de7	-0.571
s.de8	0.0577
p.de1	2.7e-25
p.de2	0.0214
p.de3	0.000378
p.de4	2.15e-49
p.de5	6.99e-34
p.de6	0.00717
p.de7	5.79e-26
p.de8	0.319

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).
Removed 2867 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d4	d5
Slc16a1	-4480	4548
Pdk4	-4455	4562
Pdhb	-4438	4550
Uqcrc2	-4471	4482
Pdha1	-4492	4434
Ndufs1	-4348	4565
Idh3b	-4476	4405
Ndufa5	-4395	4443
Ndufv2	-4459	4377
Dld	-4362	4466
Atp5a1	-4397	4414
Etfdh	-4512	4263
Ndufa9	-4441	4330
Sdha	-4439	4325
Sdhb	-4523	4244
Atp5h	-4478	4284
Atp5b	-4394	4364
Atp5j	-4493	4211
Fh1	-4295	4343
Ndufb9	-4427	4175

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Aco2	4062	553	4619	-4261	4261	1450	-1696	1944
Adhfe1	-1074	-3462	-1258	-4390	3943	1690	3288	-1597
Atp5a1	2948	945	4622	-4397	4414	3997	-3481	-323
Atp5b	4068	766	4308	-4394	4364	2977	-3385	77
Atp5c1	4840	-1751	-1307	-4262	4010	870	-3312	2861
Atp5d	4021	1286	4139	-3723	3861	1299	-1770	-1661
Atp5e	3770	-1998	4342	-4298	1823	-1601	-1827	-594
Atp5g1	3957	-451	4036	-4473	3398	-1812	-4242	975
Atp5h	4750	-2458	1887	-4478	4284	-1072	-1945	-1235
Atp5j	4083	571	3287	-4493	4211	2688	-3732	-1698
Atp5j2	4561	-152	1939	-4497	4025	2353	-4165	-2914
Atp5k	4932	3024	3909	-4469	3371	-4116	-3534	-424
Atp5l	4715	-580	-3195	-4479	3250	-865	-3557	-113
Atp5o	2413	-1474	2992	-4444	4088	1962	-2923	995
Bsg	4517	65	1399	-3987	1365	-2933	4329	575
Cox4i1	-1175	-4574	3610	-4414	3135	-1841	-3989	-612
Cox5a	1611	-1040	1373	-4430	2941	693	-3123	-253
Cox6a1	-1102	2088	-4499	-917	2193	3280	3324	3370
Cox6b1	4258	-2177	4166	-4323	3494	-128	-3942	255
Cox6c	4900	-2595	-4506	-4446	3868	-1364	-4172	2898
Cox7a2l	-626	2428	-2561	1651	3214	4329	-2731	-164
Cox7c	4806	2047	-2646	-4398	3166	389	-3892	-1664
Cox8a	-4207	-585	-4455	-4185	1126	1339	2260	-2154
Cs	1875	-3152	4451	-4002	2868	591	-3469	-819
Cyc1	1503	2753	1310	-4346	3347	1327	-4119	-22
Cycs	4767	-846	-4409	-4041	3952	1621	-4276	2963
D2hgdh	-1776	341	1461	-3826	-3877	692	2403	-4362
Dlat	3162	-2847	1910	-4368	3652	-2451	-4506	-1578
Dld	4144	-601	-1398	-4362	4466	3847	-3015	2744
Dlst	3103	-355	4283	-3926	3815	-302	-3229	1620
Etfa	4161	-3825	-3087	-4481	4091	-929	-4065	2431
Etfb	4620	-3428	-1109	-4324	4063	297	-4081	-762
Etfdh	4870	-4299	-2693	-4512	4263	-2453	-4046	2376
Fh1	3656	-1024	885	-4295	4343	3201	-3781	2780
Idh1	-1614	-1293	-3281	-4117	4109	3450	4443	4014
Idh2	2111	-4364	-4509	-4555	3931	-1689	-4496	-343
Idh3a	3768	-2535	3175	-4319	4144	2909	-3324	506
Idh3b	3245	-2354	1776	-4476	4405	3574	-3482	2625
Idh3g	2704	-1177	4584	-4113	3653	-495	-3626	170
L2hgdh	2737	941	71	-753	3937	1952	-4388	-2133
Ldha	784	-536	4516	-1809	-1228	2705	3438	-1611
Ldhb	1802	-4369	-4574	-4560	3686	-622	-4442	1217
Mdh2	3964	-1814	4548	-4216	3980	-551	-4127	-1788
Ndufa1	3432	-383	3376	-4387	1952	-1331	-2840	-2147
Ndufa10	3925	-334	3385	-4073	3377	270	-2791	785
Ndufa11	2993	-41	1113	-4258	3620	-882	-4279	-1778
Ndufa12	3940	2800	-1158	-4312	3655	2183	104	1370
Ndufa13	1127	3860	4429	-3474	2566	3228	-2027	-3286
Ndufa2	4548	518	-1035	-4114	1960	-2646	-3184	2364
Ndufa3	-279	-3509	2228	-4275	-397	-2891	-3544	757
Ndufa4	4834	452	-4309	-4465	3701	-1399	-3393	1433
Ndufa5	4837	-2935	-4349	-4395	4443	13	-3958	1270
Ndufa6	4218	1447	-1298	-4382	3157	1678	-3467	940
Ndufa7	3722	1224	4336	-3212	1849	1076	-888	-1835
Ndufa8	2434	-3720	3987	-4084	4120	-3630	-3263	419
Ndufa9	3718	1825	2947	-4441	4330	3751	-4049	1594
Ndufab1	3293	-299	-2206	-4496	2624	-1602	-3559	1851
Ndufb10	3495	-670	1622	-4247	2990	-3372	-3824	2964
Ndufb2	4542	2377	-504	-4162	1707	1114	-3398	3788
Ndufb3	2969	1263	-1172	-4343	3772	-249	-4478	319
Ndufb4	4117	621	-3319	-3792	585	559	-3382	1548
Ndufb5	4492	-753	609	-4092	3907	1235	-3974	3218
Ndufb6	-546	1726	4296	-2521	2877	1543	-3764	-1925
Ndufb7	3371	-1622	-2094	-3405	4451	-655	-3896	-2687
Ndufb9	4636	210	-1144	-4427	4175	-1016	-3434	-593
Ndufc1	2311	-138	-210	-3543	1624	-3057	-3387	-137
Ndufc2	4412	3377	-831	-3536	3116	2944	-1475	-850
Ndufs1	4521	-807	3129	-4348	4565	4277	-4268	2066
Ndufs2	3034	983	4195	-4254	3039	1660	-1673	2225
Ndufs3	2939	1072	4241	-4290	3921	2762	-1745	-1440
Ndufs4	4549	695	2262	-4228	2802	-10	-4120	-742
Ndufs5	4431	-837	1012	-3731	3668	-369	-2953	-2022
Ndufs6	4588	2591	3034	-3168	3543	1758	-4212	-1251
Ndufs7	2274	-462	2640	-4037	1436	-1678	-2420	-2863
Ndufs8	2152	-54	1185	-4340	3565	2046	-3720	3192
Ndufv1	3108	-1107	1305	-4280	4234	87	-4471	-3189
Ndufv2	4042	-2284	-3030	-4459	4377	3544	-2872	1644
Ndufv3	2259	1048	4042	-3906	164	-3497	36	-2705
Nnt	-2358	-4629	-4357	-3978	1178	27	-4352	792
Ogdh	2648	-3481	1940	-3440	4008	-13	-3477	2600
Pdha1	4513	-2900	3168	-4492	4434	2981	-3231	1711
Pdhb	3521	-658	-2310	-4438	4550	3700	-2955	3034
Pdhx	3258	2622	4376	-3287	2984	835	-3537	-78
Pdk1	3253	-2409	-1926	-4164	3527	1763	-4508	-57
Pdk2	1913	-3006	3951	-2073	1375	-607	-3190	-764
Pdk4	4638	-4570	-3061	-4455	4562	1534	3808	4201
Pdp1	3986	4490	2039	-32	-1174	1085	-2695	-4425
Pdp2	-3983	-4437	855	2035	3188	3061	762	4328
Pdpr	4134	-2855	-942	-3740	3731	-584	-4048	3397
Sdha	2192	-1566	4157	-4439	4325	3442	-3882	-288
Sdhb	4623	-4252	-3127	-4523	4244	-2808	-4466	1549
Sdhc	2779	-550	3305	-4432	3246	291	-3674	-765
Sdhd	4666	1252	3409	-3671	4033	-1412	-3835	6
Slc16a1	4915	-907	228	-4480	4548	233	-3304	4480
Slc16a3	4361	4520	3044	4223	-1586	2273	1247	-1984
Sucla2	4024	-1059	1080	-4157	4242	2517	-3616	1946
Suclg1	420	-2186	2740	-3000	1056	1438	-3949	1036
Suclg2	2567	-320	3069	-3785	3545	2729	-3395	-3209
Ucp2	-4690	2516	-2671	3195	-3703	2678	4272	-3047
Ucp3	2156	-513	3160	1016	4607	4595	4646	3946
Uqcr11	3467	-1012	4207	-4449	3297	-1037	-2282	-3852
Uqcrb	4203	1643	-306	-4338	3284	3290	-3668	-35
Uqcrc1	4032	2125	3722	-4269	2203	-1682	-4293	-1080
Uqcrc2	2858	-3601	2012	-4471	4482	3812	-3908	1703
Uqcrfs1	4443	792	2619	-4440	4029	2622	-4115	-237
Uqcrh	4460	364	78	-4287	3436	1889	-3148	-973
Uqcrq	4294	-1862	-317	-4425	2925	-2147	-4424	1023

---

---

REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX

REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX

metric	value
setSize	11
pMANOVA	8.02e-08
p.adjustMANOVA	1.11e-06
s.dist	1.33
s.de1	0.59
s.de2	-0.321
s.de3	0.124
s.de4	-0.639
s.de5	0.693
s.de6	0.29
s.de7	-0.522
s.de8	0.238
p.de1	0.00102
p.de2	0.0515
p.de3	0.475
p.de4	0.000128
p.de5	7.28e-05
p.de6	0.0875
p.de7	0.00197
p.de8	0.156

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).
Removed 2867 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d5	d4
Pdk4	4562	-4455
Pdhb	4550	-4438
Pdha1	4434	-4492
Dld	4466	-4362
Dlat	3652	-4368
Pdk1	3527	-4164
Pdpr	3731	-3740
Pdhx	2984	-3287
Pdk2	1375	-2073

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Dlat	3162	-2847	1910	-4368	3652	-2451	-4506	-1578
Dld	4144	-601	-1398	-4362	4466	3847	-3015	2744
Pdha1	4513	-2900	3168	-4492	4434	2981	-3231	1711
Pdhb	3521	-658	-2310	-4438	4550	3700	-2955	3034
Pdhx	3258	2622	4376	-3287	2984	835	-3537	-78
Pdk1	3253	-2409	-1926	-4164	3527	1763	-4508	-57
Pdk2	1913	-3006	3951	-2073	1375	-607	-3190	-764
Pdk4	4638	-4570	-3061	-4455	4562	1534	3808	4201
Pdp1	3986	4490	2039	-32	-1174	1085	-2695	-4425
Pdp2	-3983	-4437	855	2035	3188	3061	762	4328
Pdpr	4134	-2855	-942	-3740	3731	-584	-4048	3397

---

---

REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE

REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE

metric	value
setSize	38
pMANOVA	7.68e-30
p.adjustMANOVA	3.62e-28
s.dist	1.29
s.de1	0.509
s.de2	-0.297
s.de3	0.24
s.de4	-0.724
s.de5	0.66
s.de6	0.221
s.de7	-0.482
s.de8	0.12
p.de1	1.75e-07
p.de2	0.000793
p.de3	0.00872
p.de4	6.61e-16
p.de5	2.43e-12
p.de6	0.0166
p.de7	1.12e-07
p.de8	0.192

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).
Removed 2867 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d4	d5
Slc16a1	-4480	4548
Pdk4	-4455	4562
Pdhb	-4438	4550
Pdha1	-4492	4434
Idh3b	-4476	4405
Dld	-4362	4466
Sdha	-4439	4325
Sdhb	-4523	4244
Fh1	-4295	4343
Aco2	-4261	4261
Idh2	-4555	3931
Idh3a	-4319	4144
Sucla2	-4157	4242
Adhfe1	-4390	3943
Idh1	-4117	4109
Ldhb	-4560	3686
Mdh2	-4216	3980
Dlat	-4368	3652
Idh3g	-4113	3653
Dlst	-3926	3815

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Aco2	4062	553	4619	-4261	4261	1450	-1696	1944
Adhfe1	-1074	-3462	-1258	-4390	3943	1690	3288	-1597
Bsg	4517	65	1399	-3987	1365	-2933	4329	575
Cs	1875	-3152	4451	-4002	2868	591	-3469	-819
D2hgdh	-1776	341	1461	-3826	-3877	692	2403	-4362
Dlat	3162	-2847	1910	-4368	3652	-2451	-4506	-1578
Dld	4144	-601	-1398	-4362	4466	3847	-3015	2744
Dlst	3103	-355	4283	-3926	3815	-302	-3229	1620
Fh1	3656	-1024	885	-4295	4343	3201	-3781	2780
Idh1	-1614	-1293	-3281	-4117	4109	3450	4443	4014
Idh2	2111	-4364	-4509	-4555	3931	-1689	-4496	-343
Idh3a	3768	-2535	3175	-4319	4144	2909	-3324	506
Idh3b	3245	-2354	1776	-4476	4405	3574	-3482	2625
Idh3g	2704	-1177	4584	-4113	3653	-495	-3626	170
L2hgdh	2737	941	71	-753	3937	1952	-4388	-2133
Ldha	784	-536	4516	-1809	-1228	2705	3438	-1611
Ldhb	1802	-4369	-4574	-4560	3686	-622	-4442	1217
Mdh2	3964	-1814	4548	-4216	3980	-551	-4127	-1788
Nnt	-2358	-4629	-4357	-3978	1178	27	-4352	792
Ogdh	2648	-3481	1940	-3440	4008	-13	-3477	2600
Pdha1	4513	-2900	3168	-4492	4434	2981	-3231	1711
Pdhb	3521	-658	-2310	-4438	4550	3700	-2955	3034
Pdhx	3258	2622	4376	-3287	2984	835	-3537	-78
Pdk1	3253	-2409	-1926	-4164	3527	1763	-4508	-57
Pdk2	1913	-3006	3951	-2073	1375	-607	-3190	-764
Pdk4	4638	-4570	-3061	-4455	4562	1534	3808	4201
Pdp1	3986	4490	2039	-32	-1174	1085	-2695	-4425
Pdp2	-3983	-4437	855	2035	3188	3061	762	4328
Pdpr	4134	-2855	-942	-3740	3731	-584	-4048	3397
Sdha	2192	-1566	4157	-4439	4325	3442	-3882	-288
Sdhb	4623	-4252	-3127	-4523	4244	-2808	-4466	1549
Sdhc	2779	-550	3305	-4432	3246	291	-3674	-765
Sdhd	4666	1252	3409	-3671	4033	-1412	-3835	6
Slc16a1	4915	-907	228	-4480	4548	233	-3304	4480
Slc16a3	4361	4520	3044	4223	-1586	2273	1247	-1984
Sucla2	4024	-1059	1080	-4157	4242	2517	-3616	1946
Suclg1	420	-2186	2740	-3000	1056	1438	-3949	1036
Suclg2	2567	-320	3069	-3785	3545	2729	-3395	-3209

---

---

REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS

REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS

metric	value
setSize	11
pMANOVA	7.59e-06
p.adjustMANOVA	6.27e-05
s.dist	1.21
s.de1	0.154
s.de2	0.509
s.de3	0.585
s.de4	0.445
s.de5	0.0684
s.de6	0.588
s.de7	0.5
s.de8	-0.177
p.de1	0.457
p.de2	0.0022
p.de3	0.00047
p.de4	0.00687
p.de5	0.774
p.de6	0.000453
p.de7	0.00319
p.de8	0.268

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).
Removed 2867 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d6	d3
Phka1	4350	4623
Pygm	4147	4637
Agl	4332	4364
Phkb	4328	4356
Phkg1	3773	4099
Pgm1	2864	4524
Gyg	2545	4048
Phkg2	3134	3182

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Agl	260	2630	4364	4335	117	4332	-1292	-3049
Calm1	468	-3493	4625	3725	-622	-188	2394	-2143
Gyg	4789	2601	4048	-2819	3195	2545	3548	2116
Pgm1	2678	3087	4524	3608	-1443	2864	2623	-2842
Phka1	3112	4550	4623	4628	186	4350	3544	1034
Phka2	13	3506	-3856	-1139	3899	4258	926	2
Phkb	2198	3585	4356	3477	482	4328	3407	-1071
Phkg1	1150	3400	4099	4490	231	3773	2445	-2468
Phkg2	-2369	3414	3182	2042	533	3134	1757	2892
Pygb	-2215	642	-3273	-2409	-3600	-2468	4049	-3004
Pygm	-825	3210	4637	4557	-1060	4147	4059	-1115

---

---

REACTOME_COMPLEMENT_CASCADE

REACTOME_COMPLEMENT_CASCADE

metric	value
setSize	10
pMANOVA	0.000129
p.adjustMANOVA	0.000905
s.dist	1.15
s.de1	-0.565
s.de2	0.3
s.de3	-0.542
s.de4	0.526
s.de5	-0.517
s.de6	0.266
s.de7	0.12
s.de8	-0.0241
p.de1	0.00102
p.de2	0.0859
p.de3	0.00166
p.de4	0.00232
p.de5	0.00256
p.de6	0.136
p.de7	0.503
p.de8	0.866

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).
Removed 2867 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d1	d3
Cfd	-4767	-4605
C1qa	-4301	-4355
C4b	-4059	-4586
C3	-4245	-4371
Cr1l	-4219	-4228
C1s1	-336	-2683
C1qb	-4110	-49

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
C1qa	-4301	3813	-4355	4196	-3018	4534	-1050	-734
C1qb	-4110	4323	-49	3532	-4085	4173	2026	3227
C1qc	-4150	2655	2949	4614	-662	4543	-100	-1996
C1s1	-336	-2411	-2683	540	-1901	-2988	1738	-2308
C3	-4245	2892	-4371	4650	-4489	2832	1283	-243
C4b	-4059	4562	-4586	4534	-3719	1972	1841	-592
C7	3024	1440	-1600	2775	668	-2287	2289	92
Cfd	-4767	2279	-4605	4693	-3860	378	-1977	-3376
Cr1l	-4219	-3884	-4228	-1966	-2717	1010	504	973
Pros1	671	-1140	-2751	-1340	-2924	-1541	-27	3615

---

---

REACTOME_PYRUVATE_METABOLISM

REACTOME_PYRUVATE_METABOLISM

metric	value
setSize	16
pMANOVA	1.9e-08
p.adjustMANOVA	3.2e-07
s.dist	1.15
s.de1	0.611
s.de2	-0.236
s.de3	0.144
s.de4	-0.58
s.de5	0.574
s.de6	0.223
s.de7	-0.347
s.de8	0.199
p.de1	4.02e-05
p.de2	0.0832
p.de3	0.313
p.de4	2.73e-05
p.de5	8.19e-05
p.de6	0.116
p.de7	0.0129
p.de8	0.154

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).
Removed 2867 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d1	d4
Slc16a1	4915	-4480
Pdk4	4638	-4455
Pdha1	4513	-4492
Dld	4144	-4362
Bsg	4517	-3987
Pdhb	3521	-4438
Pdpr	4134	-3740
Dlat	3162	-4368
Pdk1	3253	-4164
Pdhx	3258	-3287
Ldhb	1802	-4560
Pdk2	1913	-2073
Ldha	784	-1809
Pdp1	3986	-32

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Bsg	4517	65	1399	-3987	1365	-2933	4329	575
Dlat	3162	-2847	1910	-4368	3652	-2451	-4506	-1578
Dld	4144	-601	-1398	-4362	4466	3847	-3015	2744
Ldha	784	-536	4516	-1809	-1228	2705	3438	-1611
Ldhb	1802	-4369	-4574	-4560	3686	-622	-4442	1217
Pdha1	4513	-2900	3168	-4492	4434	2981	-3231	1711
Pdhb	3521	-658	-2310	-4438	4550	3700	-2955	3034
Pdhx	3258	2622	4376	-3287	2984	835	-3537	-78
Pdk1	3253	-2409	-1926	-4164	3527	1763	-4508	-57
Pdk2	1913	-3006	3951	-2073	1375	-607	-3190	-764
Pdk4	4638	-4570	-3061	-4455	4562	1534	3808	4201
Pdp1	3986	4490	2039	-32	-1174	1085	-2695	-4425
Pdp2	-3983	-4437	855	2035	3188	3061	762	4328
Pdpr	4134	-2855	-942	-3740	3731	-584	-4048	3397
Slc16a1	4915	-907	228	-4480	4548	233	-3304	4480
Slc16a3	4361	4520	3044	4223	-1586	2273	1247	-1984

---

---

REACTOME_PEPTIDE_CHAIN_ELONGATION

REACTOME_PEPTIDE_CHAIN_ELONGATION

metric	value
setSize	67
pMANOVA	1.21e-44
p.adjustMANOVA	1.42e-42
s.dist	1.07
s.de1	-0.506
s.de2	0.248
s.de3	-0.126
s.de4	-0.249
s.de5	-0.469
s.de6	0.183
s.de7	0.684
s.de8	-0.187
p.de1	2.53e-14
p.de2	0.000284
p.de3	0.082
p.de4	0.000529
p.de5	6.63e-13
p.de6	0.00873
p.de7	1.24e-23
p.de8	0.0044

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning: Removed 2 rows containing non-finite values (stat_ydensity).

Warning: Removed 2 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d7	d1
Rpl12	4489	-4664
Rps4x	4507	-4476
Rps3	4369	-4613
Rplp0	4627	-4122
Rpl8	4596	-4099
Rps3a1	4603	-4063
Rpl3	3954	-4706
Rps9	4416	-4204
Rpl6	4546	-3907
Rps6	3845	-4508
Rps23	4324	-3948
Eef1a1	3557	-4737
Rps24	4214	-3987
Rpl38	4164	-4020
Rps16	4200	-3928
Rps7	3680	-4463
Rpl14	4686	-3484
Rpsa	4336	-3686
Rpl18a	3690	-4328
Rps25	4421	-3603

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Eef1a1	-4737.0	1057.0	-4555.0	4491.0	-4575.0	3799.0	3557.0	-2099.0
Eef2	-2019.0	720.0	1542.0	3786.0	-719.0	4446.0	4592.0	-507.0
Rpl10a	-1894.0	3571.0	-3834.0	2405.0	1149.0	1503.0	4350.0	846.0
Rpl11	-4496.0	1016.0	-4540.0	-2626.0	-2907.0	1099.0	752.0	-1922.0
Rpl12	-4664.0	281.0	-448.0	-793.0	-3814.0	4564.0	4489.0	-3529.0
Rpl13	-2756.0	1005.0	1051.0	841.0	611.0	3549.0	4241.0	-1591.0
Rpl14	-3484.0	2450.0	747.0	2965.0	-4204.0	-2832.0	4686.0	850.0
Rpl15	-2333.0	682.0	-2391.0	-1716.0	-434.0	145.0	4528.0	-2820.0
Rpl18	-2246.0	673.0	-464.0	-3786.0	-3107.0	828.0	3782.0	516.0
Rpl18a	-4328.0	2967.0	-1120.0	-1960.0	-1241.0	4412.0	3690.0	-90.0
Rpl19	-1606.0	1822.0	1611.0	-3606.0	-3471.0	-443.0	4499.0	-1853.0
Rpl22	-2109.0	-1577.0	-3978.0	3499.0	-1985.0	1261.0	3149.0	3311.0
Rpl23	-3347.0	-63.0	-2300.0	-4230.0	-2408.0	2686.0	3439.0	-793.0
Rpl23a	-1819.0	-1151.0	-2451.0	-3004.0	-1501.0	-226.0	3929.0	-128.0
Rpl24	2028.0	-1516.0	3293.0	-4019.0	-179.0	-1427.0	4426.0	-3218.0
Rpl26	-3053.0	1295.0	-4458.0	-997.0	-990.0	2647.0	3976.0	1105.0
Rpl27-ps3	1035.5	-4491.5	-977.5	-4204.5	392.5	-3423.5	595.5	97.5
Rpl27a	-765.0	3469.0	-283.0	-562.0	-4092.0	-2771.0	3658.0	-311.0
Rpl28	-3471.0	384.0	-3058.0	-731.0	-2274.0	934.0	3355.0	1698.0
Rpl29	-1550.0	1580.0	3636.0	-1529.0	168.0	618.0	1645.0	-3018.0
Rpl3	-4706.0	641.0	-4117.0	1354.0	-4672.0	-2254.0	3954.0	-3698.0
Rpl30	-4102.0	753.0	-4245.0	2797.0	-2289.0	1925.0	2942.0	2148.0
Rpl32	-2111.0	-114.0	-2493.0	-3242.0	-3875.0	-2355.0	4150.0	758.0
Rpl34	-1902.0	264.0	-2162.0	-2311.0	-3651.0	30.0	809.0	-346.0
Rpl35	-260.0	944.0	1544.0	-3339.0	501.0	1258.0	3955.0	1094.0
Rpl36al	-390.0	-968.0	2202.0	-3883.0	2525.0	3903.0	4182.0	-2045.0
Rpl37	-885.0	-3821.0	2983.0	-4392.0	-150.0	-1608.0	3687.0	-3038.0
Rpl37a	-4109.0	4049.0	548.0	-2516.0	-3379.0	3349.0	1579.0	-738.0
Rpl38	-4020.0	685.0	1227.0	-4372.0	-2807.0	2646.0	4164.0	-2260.0
Rpl39	2029.0	-908.0	-3610.0	-2995.0	-3301.0	-2757.0	633.0	89.0
Rpl3l	4079.0	-1994.0	1273.0	-3652.0	2840.0	-2171.0	-1577.0	500.0
Rpl4	-2436.0	1640.0	704.0	2374.0	-3375.0	2858.0	4681.0	2121.0
Rpl41	-569.0	688.0	-4588.0	-2653.0	-3790.0	-3147.0	3336.0	116.0
Rpl5	-4205.0	3942.0	-4600.0	3080.0	-3141.0	4170.0	2526.0	-272.0
Rpl6	-3907.0	935.0	2495.0	1234.0	-2151.0	2533.0	4546.0	580.0
Rpl8	-4099.0	1539.0	2520.0	676.0	-3408.0	-747.0	4596.0	-1407.0
Rplp0	-4122.0	1684.0	26.0	-47.0	-4420.0	2302.0	4627.0	-2369.0
Rplp1	-401.0	3710.0	-2113.0	-1112.0	-2215.0	1847.0	788.0	-1516.0
Rplp2	-3535.0	2764.0	3261.0	-2224.0	-1456.0	-823.0	2455.0	-2310.0
Rps11	-3099.0	37.0	731.0	-51.0	-3394.0	1460.0	1692.0	-3745.0
Rps12-ps3	-1676.0	NA	-4602.0	-4371.0	666.0	326.0	403.0	NA
Rps13	-3742.0	3659.0	2589.0	2506.0	-2969.0	-1105.0	3084.0	2082.0
Rps14	-2751.0	4064.0	-4050.0	1471.0	-4099.0	1787.0	3924.0	-2801.0
Rps15a	-3365.0	2480.0	-1674.0	-2749.0	-4205.0	-2025.0	3160.0	-125.0
Rps16	-3928.0	417.0	2289.0	1486.0	-4331.0	3460.0	4200.0	-299.0
Rps17	744.0	3046.0	-3851.0	-4065.0	-1359.0	3408.0	2365.0	316.0
Rps18	-4428.0	-2157.0	-657.0	-3732.0	-4029.0	381.0	3582.0	-887.0
Rps19	-1015.0	2899.0	-3396.0	-1095.0	-3824.0	516.0	4356.0	-188.0
Rps20	-3879.0	3874.0	3106.0	367.0	-4671.0	2731.0	3931.0	-2656.0
Rps21	-163.0	1078.0	-567.0	-4304.0	-2536.0	-4229.0	4069.0	-3318.0
Rps23	-3948.0	817.0	-3714.0	-2050.0	-3125.0	1478.0	4324.0	-1081.0
Rps24	-3987.0	195.0	-1883.0	179.0	-3255.0	1024.0	4214.0	-3146.0
Rps25	-3603.0	1296.0	4490.0	-2646.0	-3102.0	134.0	4421.0	-1871.0
Rps26	-3489.0	3699.0	1791.0	-3069.0	-4324.0	3340.0	3518.0	-2951.0
Rps27	-456.0	2984.0	-3857.0	-4315.0	-3723.0	-3843.0	4104.0	-3349.0
Rps27a	-418.0	3577.0	-2139.0	4048.0	-3761.0	-1240.0	2510.0	641.0
Rps29	4695.0	1750.0	4128.0	-4506.0	217.0	-4132.0	2325.0	-2576.0
Rps3	-4613.0	558.0	-1151.0	-1016.0	-4248.0	3067.0	4369.0	1031.0
Rps3a1	-4063.0	1143.0	2961.0	-1734.0	-2087.0	4071.0	4603.0	-889.0
Rps4x	-4476.0	3694.0	2637.0	-2229.0	-3092.0	3557.0	4507.0	-2256.0
Rps5	-2186.0	982.0	-4240.0	-1041.0	-2273.0	2525.0	4238.0	2409.0
Rps6	-4508.0	-1590.0	-3432.0	-837.0	-3496.0	730.0	3845.0	-1317.0
Rps7	-4463.0	-2011.0	-2440.0	910.0	-3663.0	2639.0	3680.0	-2178.0
Rps8	-4062.0	2318.0	3589.0	1616.0	-3146.0	3166.0	2935.0	-3655.0
Rps9	-4204.0	1585.0	3994.0	1252.0	-4213.0	-917.0	4416.0	-2708.0
Rpsa	-3686.0	3186.0	152.0	-1880.0	-2226.0	2889.0	4336.0	270.0
Uba52	4621.0	4487.0	1045.0	-3153.0	-367.0	-283.0	1322.0	733.0

---

---

REACTOME_NCAM1_INTERACTIONS

REACTOME_NCAM1_INTERACTIONS

metric	value
setSize	15
pMANOVA	5.21e-07
p.adjustMANOVA	5.58e-06
s.dist	1.04
s.de1	-0.175
s.de2	0.469
s.de3	-0.116
s.de4	0.689
s.de5	-0.29
s.de6	0.366
s.de7	-0.155
s.de8	0.316
p.de1	0.172
p.de2	0.000989
p.de3	0.395
p.de4	1.05e-06
p.de5	0.033
p.de6	0.0113
p.de7	0.281
p.de8	0.0269

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d4	d2
Col3a1	4690	4464
Col1a2	4635	4395
Col1a1	4684	4308
Col6a3	4580	3975
Col6a1	4652	3674
Prnp	4571	3682
Col5a2	4673	3431
Col5a1	4511	3237
Col4a1	4173	2514
Agrn	4057	1882
Col4a2	2228	2348
Col6a2	4634	834

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Agrn	-1014	1882	4073	4057	-4619	-3765	2188	4127
Cacna1s	3472	-3747	3886	-2003	1395	-2623	3958	2764
Cacnb1	-2165	-4061	4603	3661	-613	-1367	-2410	-4596
Col1a1	-854	4308	-3888	4684	-3755	1713	1693	2196
Col1a2	-2343	4395	-3375	4635	-1269	4560	2000	2607
Col3a1	-1493	4464	-4596	4690	-874	4309	195	553
Col4a1	-439	2514	-2284	4173	-279	-407	-1794	4364
Col4a2	-1168	2348	1772	2228	-3207	419	-257	4235
Col5a1	957	3237	-837	4511	3234	3353	331	483
Col5a2	-1153	3431	-1707	4673	619	4364	-664	3201
Col6a1	-2901	3674	-2180	4652	-2033	4487	-4354	2638
Col6a2	-32	834	3312	4634	-1441	3421	-3746	827
Col6a3	628	3975	-2546	4580	-3303	1656	-2717	3435
Nrtn	-4149	3138	-2770	-2536	-4508	4527	-3117	-3716
Prnp	1344	3682	-1825	4571	-2863	1570	-1526	-348

---

---

REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT

REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT

metric	value
setSize	42
pMANOVA	1.44e-15
p.adjustMANOVA	3.57e-14
s.dist	0.942
s.de1	0.339
s.de2	-0.167
s.de3	0.122
s.de4	-0.62
s.de5	0.479
s.de6	0.129
s.de7	-0.315
s.de8	0.000192
p.de1	0.000376
p.de2	0.0467
p.de3	0.168
p.de4	3.97e-13
p.de5	1.31e-07
p.de6	0.152
p.de7	0.000263
p.de8	0.956

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).
Removed 2867 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d4	d5
Hspa9	-4423	4464
Atp5a1	-4397	4414
Atp5b	-4394	4364
Timm8a1	-4183	4484
Aco2	-4261	4261
Slc25a4	-4271	4158
Slc25a12	-4232	4160
Timm9	-3967	4417
Timm10	-3946	4287
Hspd1	-4452	3797
Mtx2	-3885	4347
Timm44	-3954	4116
Samm50	-4116	3717
Atp5g1	-4473	3398
Idh3g	-4113	3653
Timm17a	-3382	4436
Cyc1	-4346	3347
Vdac1	-3930	3428
Tomm5	-3751	3452
Cs	-4002	2868

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Aco2	4062	553	4619	-4261	4261	1450	-1696	1944
Atp5a1	2948	945	4622	-4397	4414	3997	-3481	-323
Atp5b	4068	766	4308	-4394	4364	2977	-3385	77
Atp5g1	3957	-451	4036	-4473	3398	-1812	-4242	975
Bcs1l	-1929	-1115	-3293	-3111	2932	-2220	-3985	1338
Coq2	-1840	1007	2241	-2273	-2241	1963	4163	-3020
Cs	1875	-3152	4451	-4002	2868	591	-3469	-819
Cyc1	1503	2753	1310	-4346	3347	1327	-4119	-22
Dnajc19	938	1561	2470	-3550	-652	2682	3200	-2423
Fxn	-4333	-2601	1402	3870	-1317	945	1990	606
Gfer	4913	197	3455	293	1779	-3326	2719	-1902
Grpel1	1419	-217	2210	-1239	4276	951	-3545	-2251
Grpel2	4810	1348	-3890	-2987	1183	-1388	-2201	2304
Hscb	-556	-4534	-1028	-4130	-1827	-4298	566	19
Hspa9	3542	-2272	-2078	-4423	4464	3110	-3680	3962
Hspd1	1526	-4332	-3440	-4452	3797	589	-3245	4389
Idh3g	2704	-1177	4584	-4113	3653	-495	-3626	170
Ldhd	665	-3817	2977	-3990	-2359	-2262	-4426	-2896
Mtx1	-1025	19	-3111	-1461	-1032	-1446	-2207	1477
Mtx2	2406	54	-4034	-3885	4347	4380	-3624	2154
Pmpca	1488	-1902	-3880	-3117	198	1859	1971	-15
Pmpcb	2649	3035	-1972	-3602	2332	1654	-3733	979
Samm50	3647	3259	2822	-4116	3717	2085	-2891	2445
Slc25a12	2711	-3646	4569	-4232	4160	2082	-1651	-174
Slc25a4	4424	-469	2232	-4271	4158	2681	-3178	1084
Timm10	-1879	-4112	-4272	-3946	4287	1736	-2979	-3055
Timm13	-1824	1521	42	-2226	-994	-919	-4332	-4380
Timm17a	4667	-3445	2097	-3382	4436	-126	1228	245
Timm17b	-2984	1378	-2930	3560	-3161	3629	1107	-92
Timm22	857	392	-2494	2481	1168	937	-2934	-5
Timm23	3208	4070	2669	-4154	681	1814	3082	1560
Timm44	2941	-2182	-801	-3954	4116	1535	-1335	3350
Timm50	1705	-3633	-746	-2189	2649	-873	16	-4541
Timm8a1	4114	-4605	2633	-4183	4484	-4431	-2281	-2438
Timm8b	-3951	-4483	-3257	-2408	2794	3639	-2777	-1230
Timm9	-1338	-1863	1517	-3967	4417	542	3543	-89
Tomm20	2310	-1936	-3940	-3544	1524	212	-3446	458
Tomm22	4039	1505	2622	808	427	1142	-4258	-2541
Tomm40	1329	1205	815	-3737	640	1668	1936	-438
Tomm5	4438	-2590	-936	-3751	3452	-2210	524	2756
Tomm7	4902	244	2862	-3931	2165	-3228	-3195	-786
Vdac1	3771	-1399	3666	-3930	3428	1773	2792	473

---

---

REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX

REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX

metric	value
setSize	42
pMANOVA	4.42e-18
p.adjustMANOVA	1.6e-16
s.dist	0.939
s.de1	-0.407
s.de2	0.188
s.de3	0.0464
s.de4	-0.173
s.de5	-0.331
s.de6	0.27
s.de7	0.651
s.de8	-0.206
p.de1	1.02e-06
p.de2	0.0304
p.de3	0.445
p.de4	0.0781
p.de5	3.68e-05
p.de6	0.0018
p.de7	3.46e-14
p.de8	0.0134

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning: Removed 2 rows containing non-finite values (stat_ydensity).

Warning: Removed 2 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d7	d1
Rps4x	4507	-4476
Rps3	4369	-4613
Rps3a1	4603	-4063
Rps9	4416	-4204
Rps6	3845	-4508
Rps23	4324	-3948
Rps24	4214	-3987
Rps16	4200	-3928
Rps7	3680	-4463
Rpsa	4336	-3686
Rps25	4421	-3603
Rps18	3582	-4428
Rps20	3931	-3879
Rps26	3518	-3489
Rps8	2935	-4062
Rps13	3084	-3742
Eif2s3x	4532	-2463
Rps14	3924	-2751
Rps15a	3160	-3365
Rps5	4238	-2186

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Eif1ax	-1642	-3794	3434	-3530	-1534	1646	-831	-1285
Eif2s1	3526	2411	-449	2312	-1605	-2104	-1494	-2275
Eif2s2	4274	2919	-270	-115	3260	3954	2545	-1740
Eif2s3x	-2463	-702	-2901	2532	2656	3291	4532	2018
Eif3a	3198	-2833	3793	-94	4338	4230	3635	734
Eif3b	-2694	1653	488	1239	-570	3763	3430	-1960
Eif3c	-358	-432	3626	-1827	3983	4470	3659	-1135
Eif3d	-826	-442	2652	2681	-703	1499	3386	-892
Eif3e	-1454	-740	-3046	1714	-1910	1091	4322	3080
Eif3f	-3228	-1711	1042	550	-3130	-1119	2097	-2793
Eif3g	-775	1101	4463	-1026	3287	2971	3507	-1280
Eif3h	-2634	-2879	-4359	3011	-1488	-356	845	4143
Eif3i	2584	2009	3804	-4111	2721	758	3887	-1628
Eif3j2	1754	-667	3932	-4529	-441	3880	2557	-3819
Eif3k	-3419	-2381	2656	648	1392	547	2073	2525
Rps11	-3099	37	731	-51	-3394	1460	1692	-3745
Rps12-ps3	-1676	NA	-4602	-4371	666	326	403	NA
Rps13	-3742	3659	2589	2506	-2969	-1105	3084	2082
Rps14	-2751	4064	-4050	1471	-4099	1787	3924	-2801
Rps15a	-3365	2480	-1674	-2749	-4205	-2025	3160	-125
Rps16	-3928	417	2289	1486	-4331	3460	4200	-299
Rps17	744	3046	-3851	-4065	-1359	3408	2365	316
Rps18	-4428	-2157	-657	-3732	-4029	381	3582	-887
Rps19	-1015	2899	-3396	-1095	-3824	516	4356	-188
Rps20	-3879	3874	3106	367	-4671	2731	3931	-2656
Rps21	-163	1078	-567	-4304	-2536	-4229	4069	-3318
Rps23	-3948	817	-3714	-2050	-3125	1478	4324	-1081
Rps24	-3987	195	-1883	179	-3255	1024	4214	-3146
Rps25	-3603	1296	4490	-2646	-3102	134	4421	-1871
Rps26	-3489	3699	1791	-3069	-4324	3340	3518	-2951
Rps27	-456	2984	-3857	-4315	-3723	-3843	4104	-3349
Rps27a	-418	3577	-2139	4048	-3761	-1240	2510	641
Rps29	4695	1750	4128	-4506	217	-4132	2325	-2576
Rps3	-4613	558	-1151	-1016	-4248	3067	4369	1031
Rps3a1	-4063	1143	2961	-1734	-2087	4071	4603	-889
Rps4x	-4476	3694	2637	-2229	-3092	3557	4507	-2256
Rps5	-2186	982	-4240	-1041	-2273	2525	4238	2409
Rps6	-4508	-1590	-3432	-837	-3496	730	3845	-1317
Rps7	-4463	-2011	-2440	910	-3663	2639	3680	-2178
Rps8	-4062	2318	3589	1616	-3146	3166	2935	-3655
Rps9	-4204	1585	3994	1252	-4213	-917	4416	-2708
Rpsa	-3686	3186	152	-1880	-2226	2889	4336	270

---

---

REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE

REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE

metric	value
setSize	89
pMANOVA	2.2e-41
p.adjustMANOVA	2.07e-39
s.dist	0.907
s.de1	-0.41
s.de2	0.236
s.de3	-0.0969
s.de4	-0.205
s.de5	-0.398
s.de6	0.179
s.de7	0.575
s.de8	-0.158
p.de1	6.71e-13
p.de2	6.56e-05
p.de3	0.118
p.de4	0.00102
p.de5	1.75e-12
p.de6	0.00317
p.de7	3.49e-22
p.de8	0.00525

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning: Removed 2 rows containing non-finite values (stat_ydensity).

Warning: Removed 2 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d7	d1
Rpl12	4489	-4664
Rps4x	4507	-4476
Rps3	4369	-4613
Rplp0	4627	-4122
Rpl8	4596	-4099
Rps3a1	4603	-4063
Rpl3	3954	-4706
Rps9	4416	-4204
Rpl6	4546	-3907
Rps6	3845	-4508
Rps23	4324	-3948
Rps24	4214	-3987
Rpl38	4164	-4020
Rps16	4200	-3928
Rps7	3680	-4463
Rpl14	4686	-3484
Rpsa	4336	-3686
Rpl18a	3690	-4328
Rps25	4421	-3603
Rps18	3582	-4428

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Ddost	753.0	3306.0	317.0	2150.0	-3124.0	800.0	1064.0	-1043.0
Rpl10a	-1894.0	3571.0	-3834.0	2405.0	1149.0	1503.0	4350.0	846.0
Rpl11	-4496.0	1016.0	-4540.0	-2626.0	-2907.0	1099.0	752.0	-1922.0
Rpl12	-4664.0	281.0	-448.0	-793.0	-3814.0	4564.0	4489.0	-3529.0
Rpl13	-2756.0	1005.0	1051.0	841.0	611.0	3549.0	4241.0	-1591.0
Rpl14	-3484.0	2450.0	747.0	2965.0	-4204.0	-2832.0	4686.0	850.0
Rpl15	-2333.0	682.0	-2391.0	-1716.0	-434.0	145.0	4528.0	-2820.0
Rpl18	-2246.0	673.0	-464.0	-3786.0	-3107.0	828.0	3782.0	516.0
Rpl18a	-4328.0	2967.0	-1120.0	-1960.0	-1241.0	4412.0	3690.0	-90.0
Rpl19	-1606.0	1822.0	1611.0	-3606.0	-3471.0	-443.0	4499.0	-1853.0
Rpl22	-2109.0	-1577.0	-3978.0	3499.0	-1985.0	1261.0	3149.0	3311.0
Rpl23	-3347.0	-63.0	-2300.0	-4230.0	-2408.0	2686.0	3439.0	-793.0
Rpl23a	-1819.0	-1151.0	-2451.0	-3004.0	-1501.0	-226.0	3929.0	-128.0
Rpl24	2028.0	-1516.0	3293.0	-4019.0	-179.0	-1427.0	4426.0	-3218.0
Rpl26	-3053.0	1295.0	-4458.0	-997.0	-990.0	2647.0	3976.0	1105.0
Rpl27-ps3	1035.5	-4491.5	-977.5	-4204.5	392.5	-3423.5	595.5	97.5
Rpl27a	-765.0	3469.0	-283.0	-562.0	-4092.0	-2771.0	3658.0	-311.0
Rpl28	-3471.0	384.0	-3058.0	-731.0	-2274.0	934.0	3355.0	1698.0
Rpl29	-1550.0	1580.0	3636.0	-1529.0	168.0	618.0	1645.0	-3018.0
Rpl3	-4706.0	641.0	-4117.0	1354.0	-4672.0	-2254.0	3954.0	-3698.0
Rpl30	-4102.0	753.0	-4245.0	2797.0	-2289.0	1925.0	2942.0	2148.0
Rpl32	-2111.0	-114.0	-2493.0	-3242.0	-3875.0	-2355.0	4150.0	758.0
Rpl34	-1902.0	264.0	-2162.0	-2311.0	-3651.0	30.0	809.0	-346.0
Rpl35	-260.0	944.0	1544.0	-3339.0	501.0	1258.0	3955.0	1094.0
Rpl36al	-390.0	-968.0	2202.0	-3883.0	2525.0	3903.0	4182.0	-2045.0
Rpl37	-885.0	-3821.0	2983.0	-4392.0	-150.0	-1608.0	3687.0	-3038.0
Rpl37a	-4109.0	4049.0	548.0	-2516.0	-3379.0	3349.0	1579.0	-738.0
Rpl38	-4020.0	685.0	1227.0	-4372.0	-2807.0	2646.0	4164.0	-2260.0
Rpl39	2029.0	-908.0	-3610.0	-2995.0	-3301.0	-2757.0	633.0	89.0
Rpl3l	4079.0	-1994.0	1273.0	-3652.0	2840.0	-2171.0	-1577.0	500.0
Rpl4	-2436.0	1640.0	704.0	2374.0	-3375.0	2858.0	4681.0	2121.0
Rpl41	-569.0	688.0	-4588.0	-2653.0	-3790.0	-3147.0	3336.0	116.0
Rpl5	-4205.0	3942.0	-4600.0	3080.0	-3141.0	4170.0	2526.0	-272.0
Rpl6	-3907.0	935.0	2495.0	1234.0	-2151.0	2533.0	4546.0	580.0
Rpl8	-4099.0	1539.0	2520.0	676.0	-3408.0	-747.0	4596.0	-1407.0
Rplp0	-4122.0	1684.0	26.0	-47.0	-4420.0	2302.0	4627.0	-2369.0
Rplp1	-401.0	3710.0	-2113.0	-1112.0	-2215.0	1847.0	788.0	-1516.0
Rplp2	-3535.0	2764.0	3261.0	-2224.0	-1456.0	-823.0	2455.0	-2310.0
Rpn1	4543.0	2819.0	3641.0	-3314.0	-2478.0	-3062.0	3752.0	529.0
Rpn2	-2867.0	2609.0	-2694.0	4526.0	-4632.0	1300.0	4046.0	-1565.0
Rps11	-3099.0	37.0	731.0	-51.0	-3394.0	1460.0	1692.0	-3745.0
Rps12-ps3	-1676.0	NA	-4602.0	-4371.0	666.0	326.0	403.0	NA
Rps13	-3742.0	3659.0	2589.0	2506.0	-2969.0	-1105.0	3084.0	2082.0
Rps14	-2751.0	4064.0	-4050.0	1471.0	-4099.0	1787.0	3924.0	-2801.0
Rps15a	-3365.0	2480.0	-1674.0	-2749.0	-4205.0	-2025.0	3160.0	-125.0
Rps16	-3928.0	417.0	2289.0	1486.0	-4331.0	3460.0	4200.0	-299.0
Rps17	744.0	3046.0	-3851.0	-4065.0	-1359.0	3408.0	2365.0	316.0
Rps18	-4428.0	-2157.0	-657.0	-3732.0	-4029.0	381.0	3582.0	-887.0
Rps19	-1015.0	2899.0	-3396.0	-1095.0	-3824.0	516.0	4356.0	-188.0
Rps20	-3879.0	3874.0	3106.0	367.0	-4671.0	2731.0	3931.0	-2656.0
Rps21	-163.0	1078.0	-567.0	-4304.0	-2536.0	-4229.0	4069.0	-3318.0
Rps23	-3948.0	817.0	-3714.0	-2050.0	-3125.0	1478.0	4324.0	-1081.0
Rps24	-3987.0	195.0	-1883.0	179.0	-3255.0	1024.0	4214.0	-3146.0
Rps25	-3603.0	1296.0	4490.0	-2646.0	-3102.0	134.0	4421.0	-1871.0
Rps26	-3489.0	3699.0	1791.0	-3069.0	-4324.0	3340.0	3518.0	-2951.0
Rps27	-456.0	2984.0	-3857.0	-4315.0	-3723.0	-3843.0	4104.0	-3349.0
Rps27a	-418.0	3577.0	-2139.0	4048.0	-3761.0	-1240.0	2510.0	641.0
Rps29	4695.0	1750.0	4128.0	-4506.0	217.0	-4132.0	2325.0	-2576.0
Rps3	-4613.0	558.0	-1151.0	-1016.0	-4248.0	3067.0	4369.0	1031.0
Rps3a1	-4063.0	1143.0	2961.0	-1734.0	-2087.0	4071.0	4603.0	-889.0
Rps4x	-4476.0	3694.0	2637.0	-2229.0	-3092.0	3557.0	4507.0	-2256.0
Rps5	-2186.0	982.0	-4240.0	-1041.0	-2273.0	2525.0	4238.0	2409.0
Rps6	-4508.0	-1590.0	-3432.0	-837.0	-3496.0	730.0	3845.0	-1317.0
Rps7	-4463.0	-2011.0	-2440.0	910.0	-3663.0	2639.0	3680.0	-2178.0
Rps8	-4062.0	2318.0	3589.0	1616.0	-3146.0	3166.0	2935.0	-3655.0
Rps9	-4204.0	1585.0	3994.0	1252.0	-4213.0	-917.0	4416.0	-2708.0
Rpsa	-3686.0	3186.0	152.0	-1880.0	-2226.0	2889.0	4336.0	270.0
Sec11a	-223.0	4394.0	-871.0	-102.0	-3219.0	2390.0	995.0	499.0
Sec11c	-3718.0	3449.0	1338.0	134.0	-4780.0	1539.0	3973.0	-4485.0
Sec61a1	-4367.0	401.0	-4507.0	3401.0	-3349.0	2877.0	-1764.0	3336.0
Sec61a2	-3733.0	-4190.0	658.0	-3224.0	-712.0	565.0	593.0	-179.0
Sec61b	265.0	3529.0	2667.0	3216.0	-4390.0	-3517.0	1549.0	-3597.0
Sec61g	-4178.0	-239.0	-875.0	-3809.0	2752.0	3673.0	624.0	-1474.0
Spcs1	4097.0	4332.0	-4080.0	3638.0	3487.0	4047.0	1534.0	3094.0
Spcs2	2500.0	-137.0	-2251.0	-1222.0	-1199.0	-1430.0	4011.0	1815.0
Spcs3	-2660.0	-3242.0	443.0	-3459.0	-2189.0	-3255.0	611.0	-1391.0
Srp14	-1428.0	4006.0	-1430.0	2779.0	-4668.0	4107.0	-77.0	-2316.0
Srp19	1749.0	1042.0	-3178.0	-3175.0	1832.0	3384.0	-1608.0	2610.0
Srp54a	4383.0	-3261.0	1565.0	-4189.0	4512.0	-1171.0	866.0	-701.0
Srp68	-2440.0	-3369.0	-565.0	-469.0	1427.0	2188.0	1819.0	-707.0
Srp72	1214.0	2384.0	3516.0	941.0	1515.0	3386.0	4407.0	513.0
Srp9	-2145.0	2556.0	-2789.0	-2380.0	-2677.0	23.0	-520.0	-3090.0
Srprb	-1186.0	-2573.0	3870.0	1808.0	-1273.0	514.0	-294.0	-2651.0
Ssr1	-1599.0	3116.0	3953.0	4180.0	-335.0	93.0	3223.0	1185.0
Ssr2	-3051.0	2641.0	-1318.0	-3354.0	-2502.0	1219.0	2500.0	783.0
Ssr3	4530.0	3601.0	-2712.0	600.0	466.0	1909.0	2058.0	-2918.0
Ssr4	-3331.0	-2538.0	3337.0	-40.0	-174.0	1740.0	4367.0	1289.0
Tram1	-3916.0	-1735.0	-1814.0	3738.0	-1918.0	1873.0	-2596.0	48.0
Uba52	4621.0	4487.0	1045.0	-3153.0	-367.0	-283.0	1322.0	733.0

---

---

REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION

REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION

metric	value
setSize	83
pMANOVA	5.85e-38
p.adjustMANOVA	3.44e-36
s.dist	0.882
s.de1	-0.407
s.de2	0.177
s.de3	-0.0708
s.de4	-0.285
s.de5	-0.378
s.de6	0.172
s.de7	0.547
s.de8	-0.151
p.de1	5.34e-12
p.de2	0.00399
p.de3	0.286
p.de4	7.39e-06
p.de5	8.96e-11
p.de6	0.0062
p.de7	5.52e-19
p.de8	0.00965

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning: Removed 2 rows containing non-finite values (stat_ydensity).

Warning: Removed 2 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d7	d1
Rpl12	4489	-4664
Rps4x	4507	-4476
Rps3	4369	-4613
Rplp0	4627	-4122
Rpl8	4596	-4099
Rps3a1	4603	-4063
Rpl3	3954	-4706
Rps9	4416	-4204
Rpl6	4546	-3907
Polr2a	4331	-4055
Rps6	3845	-4508
Rps23	4324	-3948
Rps24	4214	-3987
Rpl38	4164	-4020
Rps16	4200	-3928
Rps7	3680	-4463
Rpl14	4686	-3484
Rpsa	4336	-3686
Rpl18a	3690	-4328
Rps25	4421	-3603

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Dnajc3	849.0	156.0	640.0	2501.0	-4252.0	2776.0	-248.0	-1758.0
Grsf1	4158.0	-4249.0	-661.0	-4249.0	4441.0	-2385.0	-118.0	2619.0
Gtf2f1	447.0	1152.0	-945.0	68.0	1997.0	2049.0	4406.0	-1180.0
Gtf2f2	-2196.0	2244.0	-1280.0	-3819.0	1807.0	2710.0	3202.0	253.0
Hsp90aa1	2636.0	-4071.0	-2875.0	-3904.0	-3251.0	-3962.0	-3899.0	4233.0
Ipo5	1817.0	-2131.0	3317.0	-2839.0	4241.0	3995.0	1607.0	2111.0
Polr2a	-4055.0	2581.0	2570.0	4317.0	-3143.0	-92.0	4331.0	-871.0
Polr2b	-2820.0	-708.0	1693.0	1764.0	-31.0	2089.0	-357.0	2504.0
Polr2c	-851.0	-1229.0	-1174.0	553.0	-1509.0	-34.0	2961.0	612.0
Polr2d	2488.0	2119.0	-2898.0	-4103.0	-497.0	1979.0	-617.0	-1596.0
Polr2e	-2755.0	-284.0	1607.0	-2788.0	-1869.0	1138.0	-50.0	173.0
Polr2f	-2963.0	-1959.0	-867.0	-133.0	1065.0	3045.0	-3831.0	-3942.0
Polr2g	-3267.0	1690.0	-1176.0	-1833.0	-1839.0	3963.0	459.0	1635.0
Polr2h	-3277.0	-2058.0	4551.0	-2589.0	-2026.0	2438.0	1704.0	-2054.0
Polr2i	2986.0	-2456.0	2813.0	-3597.0	410.0	-3008.0	734.0	1805.0
Polr2j	-2499.0	-1032.0	1648.0	-1681.0	-1881.0	-1805.0	-1013.0	-93.0
Polr2k	3181.0	-1180.0	-354.0	-2773.0	-280.0	1701.0	-3104.0	-3269.0
Polr2l	1527.0	4132.0	2776.0	1207.0	-448.0	908.0	956.0	-4423.0
Rpl10a	-1894.0	3571.0	-3834.0	2405.0	1149.0	1503.0	4350.0	846.0
Rpl11	-4496.0	1016.0	-4540.0	-2626.0	-2907.0	1099.0	752.0	-1922.0
Rpl12	-4664.0	281.0	-448.0	-793.0	-3814.0	4564.0	4489.0	-3529.0
Rpl13	-2756.0	1005.0	1051.0	841.0	611.0	3549.0	4241.0	-1591.0
Rpl14	-3484.0	2450.0	747.0	2965.0	-4204.0	-2832.0	4686.0	850.0
Rpl15	-2333.0	682.0	-2391.0	-1716.0	-434.0	145.0	4528.0	-2820.0
Rpl18	-2246.0	673.0	-464.0	-3786.0	-3107.0	828.0	3782.0	516.0
Rpl18a	-4328.0	2967.0	-1120.0	-1960.0	-1241.0	4412.0	3690.0	-90.0
Rpl19	-1606.0	1822.0	1611.0	-3606.0	-3471.0	-443.0	4499.0	-1853.0
Rpl22	-2109.0	-1577.0	-3978.0	3499.0	-1985.0	1261.0	3149.0	3311.0
Rpl23	-3347.0	-63.0	-2300.0	-4230.0	-2408.0	2686.0	3439.0	-793.0
Rpl23a	-1819.0	-1151.0	-2451.0	-3004.0	-1501.0	-226.0	3929.0	-128.0
Rpl24	2028.0	-1516.0	3293.0	-4019.0	-179.0	-1427.0	4426.0	-3218.0
Rpl26	-3053.0	1295.0	-4458.0	-997.0	-990.0	2647.0	3976.0	1105.0
Rpl27-ps3	1035.5	-4491.5	-977.5	-4204.5	392.5	-3423.5	595.5	97.5
Rpl27a	-765.0	3469.0	-283.0	-562.0	-4092.0	-2771.0	3658.0	-311.0
Rpl28	-3471.0	384.0	-3058.0	-731.0	-2274.0	934.0	3355.0	1698.0
Rpl29	-1550.0	1580.0	3636.0	-1529.0	168.0	618.0	1645.0	-3018.0
Rpl3	-4706.0	641.0	-4117.0	1354.0	-4672.0	-2254.0	3954.0	-3698.0
Rpl30	-4102.0	753.0	-4245.0	2797.0	-2289.0	1925.0	2942.0	2148.0
Rpl32	-2111.0	-114.0	-2493.0	-3242.0	-3875.0	-2355.0	4150.0	758.0
Rpl34	-1902.0	264.0	-2162.0	-2311.0	-3651.0	30.0	809.0	-346.0
Rpl35	-260.0	944.0	1544.0	-3339.0	501.0	1258.0	3955.0	1094.0
Rpl36al	-390.0	-968.0	2202.0	-3883.0	2525.0	3903.0	4182.0	-2045.0
Rpl37	-885.0	-3821.0	2983.0	-4392.0	-150.0	-1608.0	3687.0	-3038.0
Rpl37a	-4109.0	4049.0	548.0	-2516.0	-3379.0	3349.0	1579.0	-738.0
Rpl38	-4020.0	685.0	1227.0	-4372.0	-2807.0	2646.0	4164.0	-2260.0
Rpl39	2029.0	-908.0	-3610.0	-2995.0	-3301.0	-2757.0	633.0	89.0
Rpl3l	4079.0	-1994.0	1273.0	-3652.0	2840.0	-2171.0	-1577.0	500.0
Rpl4	-2436.0	1640.0	704.0	2374.0	-3375.0	2858.0	4681.0	2121.0
Rpl41	-569.0	688.0	-4588.0	-2653.0	-3790.0	-3147.0	3336.0	116.0
Rpl5	-4205.0	3942.0	-4600.0	3080.0	-3141.0	4170.0	2526.0	-272.0
Rpl6	-3907.0	935.0	2495.0	1234.0	-2151.0	2533.0	4546.0	580.0
Rpl8	-4099.0	1539.0	2520.0	676.0	-3408.0	-747.0	4596.0	-1407.0
Rplp0	-4122.0	1684.0	26.0	-47.0	-4420.0	2302.0	4627.0	-2369.0
Rplp1	-401.0	3710.0	-2113.0	-1112.0	-2215.0	1847.0	788.0	-1516.0
Rplp2	-3535.0	2764.0	3261.0	-2224.0	-1456.0	-823.0	2455.0	-2310.0
Rps11	-3099.0	37.0	731.0	-51.0	-3394.0	1460.0	1692.0	-3745.0
Rps12-ps3	-1676.0	NA	-4602.0	-4371.0	666.0	326.0	403.0	NA
Rps13	-3742.0	3659.0	2589.0	2506.0	-2969.0	-1105.0	3084.0	2082.0
Rps14	-2751.0	4064.0	-4050.0	1471.0	-4099.0	1787.0	3924.0	-2801.0
Rps15a	-3365.0	2480.0	-1674.0	-2749.0	-4205.0	-2025.0	3160.0	-125.0
Rps16	-3928.0	417.0	2289.0	1486.0	-4331.0	3460.0	4200.0	-299.0
Rps17	744.0	3046.0	-3851.0	-4065.0	-1359.0	3408.0	2365.0	316.0
Rps18	-4428.0	-2157.0	-657.0	-3732.0	-4029.0	381.0	3582.0	-887.0
Rps19	-1015.0	2899.0	-3396.0	-1095.0	-3824.0	516.0	4356.0	-188.0
Rps20	-3879.0	3874.0	3106.0	367.0	-4671.0	2731.0	3931.0	-2656.0
Rps21	-163.0	1078.0	-567.0	-4304.0	-2536.0	-4229.0	4069.0	-3318.0
Rps23	-3948.0	817.0	-3714.0	-2050.0	-3125.0	1478.0	4324.0	-1081.0
Rps24	-3987.0	195.0	-1883.0	179.0	-3255.0	1024.0	4214.0	-3146.0
Rps25	-3603.0	1296.0	4490.0	-2646.0	-3102.0	134.0	4421.0	-1871.0
Rps26	-3489.0	3699.0	1791.0	-3069.0	-4324.0	3340.0	3518.0	-2951.0
Rps27	-456.0	2984.0	-3857.0	-4315.0	-3723.0	-3843.0	4104.0	-3349.0
Rps27a	-418.0	3577.0	-2139.0	4048.0	-3761.0	-1240.0	2510.0	641.0
Rps29	4695.0	1750.0	4128.0	-4506.0	217.0	-4132.0	2325.0	-2576.0
Rps3	-4613.0	558.0	-1151.0	-1016.0	-4248.0	3067.0	4369.0	1031.0
Rps3a1	-4063.0	1143.0	2961.0	-1734.0	-2087.0	4071.0	4603.0	-889.0
Rps4x	-4476.0	3694.0	2637.0	-2229.0	-3092.0	3557.0	4507.0	-2256.0
Rps5	-2186.0	982.0	-4240.0	-1041.0	-2273.0	2525.0	4238.0	2409.0
Rps6	-4508.0	-1590.0	-3432.0	-837.0	-3496.0	730.0	3845.0	-1317.0
Rps7	-4463.0	-2011.0	-2440.0	910.0	-3663.0	2639.0	3680.0	-2178.0
Rps8	-4062.0	2318.0	3589.0	1616.0	-3146.0	3166.0	2935.0	-3655.0
Rps9	-4204.0	1585.0	3994.0	1252.0	-4213.0	-917.0	4416.0	-2708.0
Rpsa	-3686.0	3186.0	152.0	-1880.0	-2226.0	2889.0	4336.0	270.0
Uba52	4621.0	4487.0	1045.0	-3153.0	-367.0	-283.0	1322.0	733.0

---

---

REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION

REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION

metric	value
setSize	86
pMANOVA	2.99e-38
p.adjustMANOVA	2.01e-36
s.dist	0.878
s.de1	-0.361
s.de2	0.174
s.de3	-0.0361
s.de4	-0.226
s.de5	-0.295
s.de6	0.216
s.de7	0.633
s.de8	-0.156
p.de1	3.86e-10
p.de2	0.0039
p.de3	0.612
p.de4	0.000356
p.de5	1.68e-07
p.de6	0.000433
p.de7	1e-25
p.de8	0.00662

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning: Removed 2 rows containing non-finite values (stat_ydensity).

Warning: Removed 2 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d7	d1
Rpl12	4489	-4664
Rps4x	4507	-4476
Rps3	4369	-4613
Rplp0	4627	-4122
Rpl8	4596	-4099
Rps3a1	4603	-4063
Rpl3	3954	-4706
Rps9	4416	-4204
Rpl6	4546	-3907
Rps6	3845	-4508
Rps23	4324	-3948
Rps24	4214	-3987
Rpl38	4164	-4020
Rps16	4200	-3928
Rps7	3680	-4463
Rpl14	4686	-3484
Rpsa	4336	-3686
Rpl18a	3690	-4328
Rps25	4421	-3603
Rps18	3582	-4428

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Eif1ax	-1642.0	-3794.0	3434.0	-3530.0	-1534.0	1646.0	-831.0	-1285.0
Eif2s1	3526.0	2411.0	-449.0	2312.0	-1605.0	-2104.0	-1494.0	-2275.0
Eif2s2	4274.0	2919.0	-270.0	-115.0	3260.0	3954.0	2545.0	-1740.0
Eif2s3x	-2463.0	-702.0	-2901.0	2532.0	2656.0	3291.0	4532.0	2018.0
Eif3a	3198.0	-2833.0	3793.0	-94.0	4338.0	4230.0	3635.0	734.0
Eif3b	-2694.0	1653.0	488.0	1239.0	-570.0	3763.0	3430.0	-1960.0
Eif3c	-358.0	-432.0	3626.0	-1827.0	3983.0	4470.0	3659.0	-1135.0
Eif3d	-826.0	-442.0	2652.0	2681.0	-703.0	1499.0	3386.0	-892.0
Eif3e	-1454.0	-740.0	-3046.0	1714.0	-1910.0	1091.0	4322.0	3080.0
Eif3f	-3228.0	-1711.0	1042.0	550.0	-3130.0	-1119.0	2097.0	-2793.0
Eif3g	-775.0	1101.0	4463.0	-1026.0	3287.0	2971.0	3507.0	-1280.0
Eif3h	-2634.0	-2879.0	-4359.0	3011.0	-1488.0	-356.0	845.0	4143.0
Eif3i	2584.0	2009.0	3804.0	-4111.0	2721.0	758.0	3887.0	-1628.0
Eif3j2	1754.0	-667.0	3932.0	-4529.0	-441.0	3880.0	2557.0	-3819.0
Eif3k	-3419.0	-2381.0	2656.0	648.0	1392.0	547.0	2073.0	2525.0
Eif4a1	445.0	2385.0	1225.0	-2188.0	1097.0	1725.0	1551.0	-3707.0
Eif4a2	816.0	1590.0	1421.0	171.0	2837.0	4208.0	2556.0	3598.0
Eif4b	490.0	-1280.0	4350.0	3628.0	2423.0	4246.0	4737.0	672.0
Eif4e	4242.0	-2550.0	-3253.0	-3029.0	4069.0	-398.0	-1380.0	-541.0
Eif4g1	3133.0	596.0	3373.0	-738.0	-445.0	2383.0	1324.0	1366.0
Eif4h	4115.0	-102.0	-3220.0	-661.0	996.0	-2838.0	3634.0	-2497.0
Rpl10a	-1894.0	3571.0	-3834.0	2405.0	1149.0	1503.0	4350.0	846.0
Rpl11	-4496.0	1016.0	-4540.0	-2626.0	-2907.0	1099.0	752.0	-1922.0
Rpl12	-4664.0	281.0	-448.0	-793.0	-3814.0	4564.0	4489.0	-3529.0
Rpl13	-2756.0	1005.0	1051.0	841.0	611.0	3549.0	4241.0	-1591.0
Rpl14	-3484.0	2450.0	747.0	2965.0	-4204.0	-2832.0	4686.0	850.0
Rpl15	-2333.0	682.0	-2391.0	-1716.0	-434.0	145.0	4528.0	-2820.0
Rpl18	-2246.0	673.0	-464.0	-3786.0	-3107.0	828.0	3782.0	516.0
Rpl18a	-4328.0	2967.0	-1120.0	-1960.0	-1241.0	4412.0	3690.0	-90.0
Rpl19	-1606.0	1822.0	1611.0	-3606.0	-3471.0	-443.0	4499.0	-1853.0
Rpl22	-2109.0	-1577.0	-3978.0	3499.0	-1985.0	1261.0	3149.0	3311.0
Rpl23	-3347.0	-63.0	-2300.0	-4230.0	-2408.0	2686.0	3439.0	-793.0
Rpl23a	-1819.0	-1151.0	-2451.0	-3004.0	-1501.0	-226.0	3929.0	-128.0
Rpl24	2028.0	-1516.0	3293.0	-4019.0	-179.0	-1427.0	4426.0	-3218.0
Rpl26	-3053.0	1295.0	-4458.0	-997.0	-990.0	2647.0	3976.0	1105.0
Rpl27-ps3	1035.5	-4491.5	-977.5	-4204.5	392.5	-3423.5	595.5	97.5
Rpl27a	-765.0	3469.0	-283.0	-562.0	-4092.0	-2771.0	3658.0	-311.0
Rpl28	-3471.0	384.0	-3058.0	-731.0	-2274.0	934.0	3355.0	1698.0
Rpl29	-1550.0	1580.0	3636.0	-1529.0	168.0	618.0	1645.0	-3018.0
Rpl3	-4706.0	641.0	-4117.0	1354.0	-4672.0	-2254.0	3954.0	-3698.0
Rpl30	-4102.0	753.0	-4245.0	2797.0	-2289.0	1925.0	2942.0	2148.0
Rpl32	-2111.0	-114.0	-2493.0	-3242.0	-3875.0	-2355.0	4150.0	758.0
Rpl34	-1902.0	264.0	-2162.0	-2311.0	-3651.0	30.0	809.0	-346.0
Rpl35	-260.0	944.0	1544.0	-3339.0	501.0	1258.0	3955.0	1094.0
Rpl36al	-390.0	-968.0	2202.0	-3883.0	2525.0	3903.0	4182.0	-2045.0
Rpl37	-885.0	-3821.0	2983.0	-4392.0	-150.0	-1608.0	3687.0	-3038.0
Rpl37a	-4109.0	4049.0	548.0	-2516.0	-3379.0	3349.0	1579.0	-738.0
Rpl38	-4020.0	685.0	1227.0	-4372.0	-2807.0	2646.0	4164.0	-2260.0
Rpl39	2029.0	-908.0	-3610.0	-2995.0	-3301.0	-2757.0	633.0	89.0
Rpl3l	4079.0	-1994.0	1273.0	-3652.0	2840.0	-2171.0	-1577.0	500.0
Rpl4	-2436.0	1640.0	704.0	2374.0	-3375.0	2858.0	4681.0	2121.0
Rpl41	-569.0	688.0	-4588.0	-2653.0	-3790.0	-3147.0	3336.0	116.0
Rpl5	-4205.0	3942.0	-4600.0	3080.0	-3141.0	4170.0	2526.0	-272.0
Rpl6	-3907.0	935.0	2495.0	1234.0	-2151.0	2533.0	4546.0	580.0
Rpl8	-4099.0	1539.0	2520.0	676.0	-3408.0	-747.0	4596.0	-1407.0
Rplp0	-4122.0	1684.0	26.0	-47.0	-4420.0	2302.0	4627.0	-2369.0
Rplp1	-401.0	3710.0	-2113.0	-1112.0	-2215.0	1847.0	788.0	-1516.0
Rplp2	-3535.0	2764.0	3261.0	-2224.0	-1456.0	-823.0	2455.0	-2310.0
Rps11	-3099.0	37.0	731.0	-51.0	-3394.0	1460.0	1692.0	-3745.0
Rps12-ps3	-1676.0	NA	-4602.0	-4371.0	666.0	326.0	403.0	NA
Rps13	-3742.0	3659.0	2589.0	2506.0	-2969.0	-1105.0	3084.0	2082.0
Rps14	-2751.0	4064.0	-4050.0	1471.0	-4099.0	1787.0	3924.0	-2801.0
Rps15a	-3365.0	2480.0	-1674.0	-2749.0	-4205.0	-2025.0	3160.0	-125.0
Rps16	-3928.0	417.0	2289.0	1486.0	-4331.0	3460.0	4200.0	-299.0
Rps17	744.0	3046.0	-3851.0	-4065.0	-1359.0	3408.0	2365.0	316.0
Rps18	-4428.0	-2157.0	-657.0	-3732.0	-4029.0	381.0	3582.0	-887.0
Rps19	-1015.0	2899.0	-3396.0	-1095.0	-3824.0	516.0	4356.0	-188.0
Rps20	-3879.0	3874.0	3106.0	367.0	-4671.0	2731.0	3931.0	-2656.0
Rps21	-163.0	1078.0	-567.0	-4304.0	-2536.0	-4229.0	4069.0	-3318.0
Rps23	-3948.0	817.0	-3714.0	-2050.0	-3125.0	1478.0	4324.0	-1081.0
Rps24	-3987.0	195.0	-1883.0	179.0	-3255.0	1024.0	4214.0	-3146.0
Rps25	-3603.0	1296.0	4490.0	-2646.0	-3102.0	134.0	4421.0	-1871.0
Rps26	-3489.0	3699.0	1791.0	-3069.0	-4324.0	3340.0	3518.0	-2951.0
Rps27	-456.0	2984.0	-3857.0	-4315.0	-3723.0	-3843.0	4104.0	-3349.0
Rps27a	-418.0	3577.0	-2139.0	4048.0	-3761.0	-1240.0	2510.0	641.0
Rps29	4695.0	1750.0	4128.0	-4506.0	217.0	-4132.0	2325.0	-2576.0
Rps3	-4613.0	558.0	-1151.0	-1016.0	-4248.0	3067.0	4369.0	1031.0
Rps3a1	-4063.0	1143.0	2961.0	-1734.0	-2087.0	4071.0	4603.0	-889.0
Rps4x	-4476.0	3694.0	2637.0	-2229.0	-3092.0	3557.0	4507.0	-2256.0
Rps5	-2186.0	982.0	-4240.0	-1041.0	-2273.0	2525.0	4238.0	2409.0
Rps6	-4508.0	-1590.0	-3432.0	-837.0	-3496.0	730.0	3845.0	-1317.0
Rps7	-4463.0	-2011.0	-2440.0	910.0	-3663.0	2639.0	3680.0	-2178.0
Rps8	-4062.0	2318.0	3589.0	1616.0	-3146.0	3166.0	2935.0	-3655.0
Rps9	-4204.0	1585.0	3994.0	1252.0	-4213.0	-917.0	4416.0	-2708.0
Rpsa	-3686.0	3186.0	152.0	-1880.0	-2226.0	2889.0	4336.0	270.0
Uba52	4621.0	4487.0	1045.0	-3153.0	-367.0	-283.0	1322.0	733.0

---

---

REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM

REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM

metric	value
setSize	16
pMANOVA	0.00214
p.adjustMANOVA	0.0111
s.dist	0.86
s.de1	0.327
s.de2	-0.288
s.de3	-0.0371
s.de4	-0.459
s.de5	0.48
s.de6	-0.0355
s.de7	-0.26
s.de8	-0.194
p.de1	0.0347
p.de2	0.0348
p.de3	0.759
p.de4	0.00092
p.de5	0.00109
p.de6	0.758
p.de7	0.0626
p.de8	0.145

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d5	d4
Acat1	4467	-4518
Dld	4466	-4362
Aldh6a1	4595	-3857
Hibadh	4273	-4127
Ivd	3978	-3878
Mccc2	2769	-2522
Hibch	1552	-4227
Hsd17b10	1855	-2755
Acadsb	3187	-1591
Acad8	2038	-2211
Bckdha	1116	-3870
Dbt	3720	-188

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Acad8	1783	3322	-581	-2211	2038	3459	-3541	-1387
Acadsb	1133	3144	3188	-1591	3187	4448	607	-3080
Acat1	4085	-4436	-343	-4518	4467	-51	-4207	592
Aldh6a1	727	-4610	3021	-3857	4595	932	4018	-364
Auh	1034	-1126	-847	3095	-1563	-3779	-4287	3040
Bcat2	-920	-741	-450	1450	2267	-378	93	-1390
Bckdha	1690	-1613	1137	-3870	1116	2777	-3639	-3788
Bckdhb	-3260	-631	-3435	2118	-2856	-928	1116	585
Dbt	3931	-3788	842	-188	3720	-3591	-4144	-3908
Dld	4144	-601	-1398	-4362	4466	3847	-3015	2744
Hibadh	3936	-1755	-2841	-4127	4273	-304	-279	-926
Hibch	4356	-3553	-4025	-4227	1552	-3874	-2547	-1567
Hsd17b10	243	-964	2287	-2755	1855	-1227	4201	1182
Ivd	4450	-4120	2131	-3878	3978	-3495	-2520	-1716
Mccc1	1529	3070	700	-3145	-1137	1163	-1994	-2791
Mccc2	-1979	-4034	-2179	-2522	2769	-2231	1077	-2552

---

---

REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S

REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S

metric	value
setSize	49
pMANOVA	3.45e-17
p.adjustMANOVA	1.08e-15
s.dist	0.838
s.de1	-0.302
s.de2	0.16
s.de3	0.0533
s.de4	-0.158
s.de5	-0.241
s.de6	0.279
s.de7	0.628
s.de8	-0.164
p.de1	6.94e-05
p.de2	0.0459
p.de3	0.385
p.de4	0.0808
p.de5	0.000923
p.de6	0.000504
p.de7	2.96e-15
p.de8	0.0325

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning: Removed 2 rows containing non-finite values (stat_ydensity).

Warning: Removed 2 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d7	d1
Rps4x	4507	-4476
Rps3	4369	-4613
Rps3a1	4603	-4063
Rps9	4416	-4204
Rps6	3845	-4508
Rps23	4324	-3948
Rps24	4214	-3987
Rps16	4200	-3928
Rps7	3680	-4463
Rpsa	4336	-3686
Rps25	4421	-3603
Rps18	3582	-4428
Rps20	3931	-3879
Rps26	3518	-3489
Rps8	2935	-4062
Rps13	3084	-3742
Eif2s3x	4532	-2463
Rps14	3924	-2751
Rps15a	3160	-3365
Rps5	4238	-2186

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Eif1ax	-1642	-3794	3434	-3530	-1534	1646	-831	-1285
Eif2s1	3526	2411	-449	2312	-1605	-2104	-1494	-2275
Eif2s2	4274	2919	-270	-115	3260	3954	2545	-1740
Eif2s3x	-2463	-702	-2901	2532	2656	3291	4532	2018
Eif3a	3198	-2833	3793	-94	4338	4230	3635	734
Eif3b	-2694	1653	488	1239	-570	3763	3430	-1960
Eif3c	-358	-432	3626	-1827	3983	4470	3659	-1135
Eif3d	-826	-442	2652	2681	-703	1499	3386	-892
Eif3e	-1454	-740	-3046	1714	-1910	1091	4322	3080
Eif3f	-3228	-1711	1042	550	-3130	-1119	2097	-2793
Eif3g	-775	1101	4463	-1026	3287	2971	3507	-1280
Eif3h	-2634	-2879	-4359	3011	-1488	-356	845	4143
Eif3i	2584	2009	3804	-4111	2721	758	3887	-1628
Eif3j2	1754	-667	3932	-4529	-441	3880	2557	-3819
Eif3k	-3419	-2381	2656	648	1392	547	2073	2525
Eif4a1	445	2385	1225	-2188	1097	1725	1551	-3707
Eif4a2	816	1590	1421	171	2837	4208	2556	3598
Eif4b	490	-1280	4350	3628	2423	4246	4737	672
Eif4e	4242	-2550	-3253	-3029	4069	-398	-1380	-541
Eif4ebp1	-1375	-709	-673	1009	-1921	1628	4710	3871
Eif4g1	3133	596	3373	-738	-445	2383	1324	1366
Eif4h	4115	-102	-3220	-661	996	-2838	3634	-2497
Rps11	-3099	37	731	-51	-3394	1460	1692	-3745
Rps12-ps3	-1676	NA	-4602	-4371	666	326	403	NA
Rps13	-3742	3659	2589	2506	-2969	-1105	3084	2082
Rps14	-2751	4064	-4050	1471	-4099	1787	3924	-2801
Rps15a	-3365	2480	-1674	-2749	-4205	-2025	3160	-125
Rps16	-3928	417	2289	1486	-4331	3460	4200	-299
Rps17	744	3046	-3851	-4065	-1359	3408	2365	316
Rps18	-4428	-2157	-657	-3732	-4029	381	3582	-887
Rps19	-1015	2899	-3396	-1095	-3824	516	4356	-188
Rps20	-3879	3874	3106	367	-4671	2731	3931	-2656
Rps21	-163	1078	-567	-4304	-2536	-4229	4069	-3318
Rps23	-3948	817	-3714	-2050	-3125	1478	4324	-1081
Rps24	-3987	195	-1883	179	-3255	1024	4214	-3146
Rps25	-3603	1296	4490	-2646	-3102	134	4421	-1871
Rps26	-3489	3699	1791	-3069	-4324	3340	3518	-2951
Rps27	-456	2984	-3857	-4315	-3723	-3843	4104	-3349
Rps27a	-418	3577	-2139	4048	-3761	-1240	2510	641
Rps29	4695	1750	4128	-4506	217	-4132	2325	-2576
Rps3	-4613	558	-1151	-1016	-4248	3067	4369	1031
Rps3a1	-4063	1143	2961	-1734	-2087	4071	4603	-889
Rps4x	-4476	3694	2637	-2229	-3092	3557	4507	-2256
Rps5	-2186	982	-4240	-1041	-2273	2525	4238	2409
Rps6	-4508	-1590	-3432	-837	-3496	730	3845	-1317
Rps7	-4463	-2011	-2440	910	-3663	2639	3680	-2178
Rps8	-4062	2318	3589	1616	-3146	3166	2935	-3655
Rps9	-4204	1585	3994	1252	-4213	-917	4416	-2708
Rpsa	-3686	3186	152	-1880	-2226	2889	4336	270

---

---

REACTOME_ADP_SIGNALLING_THROUGH_P2RY1

REACTOME_ADP_SIGNALLING_THROUGH_P2RY1

metric	value
setSize	11
pMANOVA	0.0013
p.adjustMANOVA	0.00711
s.dist	0.827
s.de1	-0.316
s.de2	-0.397
s.de3	-0.155
s.de4	-0.501
s.de5	0.00543
s.de6	-0.355
s.de7	-0.154
s.de8	-0.0528
p.de1	0.0464
p.de2	0.0161
p.de3	0.336
p.de4	0.00273
p.de5	0.933
p.de6	0.0288
p.de7	0.359
p.de8	0.725

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d4	d2
P2ry1	-4456	-4086
Gng5	-4265	-3874
Gnb5	-3207	-4561
Gnb4	-2165	-4494
Gnb1	-3614	-1610
Gnaq	-2714	-963
Mapk14	-273	-1864

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Gna11	1043	-3655	-3584	1570	-3318	-2555	-4407	1195
Gnaq	-743	-963	-4281	-2714	-3226	-3312	-609	1804
Gnb1	-788	-1610	2490	-3614	-1786	-4364	1918	-2370
Gnb2	-2386	297	454	-2563	770	-3158	-271	-2637
Gnb4	-3608	-4494	-2203	-2165	2059	-3021	3515	2006
Gnb5	-1125	-4561	197	-3207	4318	-2335	-3	701
Gng11	-1347	704	-946	-472	-2149	-400	-4149	-4205
Gng12	-2886	2876	-2224	-3829	-3648	1903	4321	1808
Gng5	1271	-3874	678	-4265	2596	-1310	-3904	-1132
Mapk14	-1738	-1864	3709	-273	-1451	-2513	-1366	-1401
P2ry1	-3522	-4086	-2489	-4456	4387	1753	-2487	1221

---

---

REACTOME_REGULATION_OF_KIT_SIGNALING

REACTOME_REGULATION_OF_KIT_SIGNALING

metric	value
setSize	12
pMANOVA	0.00968
p.adjustMANOVA	0.0404
s.dist	0.825
s.de1	-0.301
s.de2	0.073
s.de3	-0.677
s.de4	0.00997
s.de5	-0.28
s.de6	-0.147
s.de7	0.141
s.de8	0.0762
p.de1	0.264
p.de2	0.942
p.de3	2e-04
p.de4	0.941
p.de5	0.421
p.de6	0.218
p.de7	0.61
p.de8	0.695

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning: Removed 3 rows containing non-finite values (stat_density2d).
Removed 3 rows containing non-finite values (stat_density2d).

Warning: Removed 3 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning: Removed 3 rows containing non-finite values (stat_density2d).
Removed 3 rows containing non-finite values (stat_density2d).
Removed 3 rows containing non-finite values (stat_density2d).

Warning: Removed 3 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 3 rows containing non-finite values (stat_density2d).
Removed 3 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning: Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 3 rows containing non-finite values (stat_density2d).
Removed 3 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning: Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 3 rows containing non-finite values (stat_density2d).
Removed 3 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning: Removed 3 rows containing non-finite values (stat_density2d).
Removed 3 rows containing non-finite values (stat_density2d).
Removed 3 rows containing non-finite values (stat_density2d).
Removed 3 rows containing non-finite values (stat_density2d).
Removed 3 rows containing non-finite values (stat_density2d).
Removed 3 rows containing non-finite values (stat_density2d).
Removed 3 rows containing non-finite values (stat_density2d).

Warning: Removed 3 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning: Removed 3 rows containing missing values (geom_point).
Removed 3 rows containing missing values (geom_point).

Warning: Removed 3 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning: Removed 3 rows containing missing values (geom_point).
Removed 3 rows containing missing values (geom_point).
Removed 3 rows containing missing values (geom_point).

Warning: Removed 3 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 3 rows containing missing values (geom_point).
Removed 3 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning: Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).

Warning: Removed 3 rows containing missing values (geom_point).
Removed 3 rows containing missing values (geom_point).

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning: Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).

Warning: Removed 3 rows containing missing values (geom_point).
Removed 3 rows containing missing values (geom_point).

Warning: Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning: Removed 3 rows containing missing values (geom_point).
Removed 3 rows containing missing values (geom_point).
Removed 3 rows containing missing values (geom_point).
Removed 3 rows containing missing values (geom_point).
Removed 3 rows containing missing values (geom_point).
Removed 3 rows containing missing values (geom_point).
Removed 3 rows containing missing values (geom_point).

Warning: Removed 3 rows containing non-finite values (stat_bin).

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning: Removed 16 rows containing non-finite values (stat_ydensity).

Warning: Removed 16 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d3	d1
Cbl	-4017	-4268
Grb2	-3912	-3931
Kitl	-4217	-3549
Sh2b3	-3106	-2917
Fyn	-4289	-974

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Cbl	-4268	2459	-4017	28	-4471	-1549	-765	-2509
Fyn	-974	3967	-4289	-2943	-3846	-2982	2358	381
Grb2	-3931	-2002	-3912	704	-4125	-1531	2501	-472
Kitl	-3549	-3892	-4217	-4377	1620	40	3436	3320
Lyn	-4120	2875	NA	NA	-4725	2425	2689	NA
Prkca	1012	2681	-3447	2104	-824	3464	-2678	-1822
Ptpn6	-4695	NA	NA	NA	-4827	NA	NA	NA
Sh2b3	-2917	3649	-3106	3710	-2869	-853	3403	1599
Socs1	-307	NA	NA	NA	NA	NA	NA	NA
Socs6	2565	-4047	-3846	2248	3512	-1138	-2668	3252
Sos1	925	-4117	-375	-3693	1777	-2489	3701	684
Yes1	3869	1927	-2347	3267	2066	-2802	-4433	-1257

---

---

REACTOME_SIGNALING_BY_HIPPO

REACTOME_SIGNALING_BY_HIPPO

metric	value
setSize	15
pMANOVA	0.000566
p.adjustMANOVA	0.00346
s.dist	0.816
s.de1	-0.184
s.de2	0.124
s.de3	0.0327
s.de4	0.12
s.de5	-0.453
s.de6	0.0845
s.de7	-0.143
s.de8	-0.608
p.de1	0.153
p.de2	0.391
p.de3	0.846
p.de4	0.383
p.de5	0.00116
p.de6	0.584
p.de7	0.32
p.de8	1.32e-05

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d8	d5
Wwtr1	-4576	-3959
Yap1	-3896	-4608
Tjp1	-4149	-3511
Stk4	-4306	-2529
Ywhae	-4235	-2482
Sav1	-4447	-2291
Ywhab	-2102	-4325
Lats2	-2285	-3895
Amotl2	-1723	-4076
Amot	-3877	-1711
Mob1a	-2323	-1793
Mob1b	-1623	-2173
Dvl2	-2983	-493

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Amot	4065	4156	1587	3929	-1711	-1964	-4597	-3877
Amotl1	1930	339	3624	-152	812	2338	-142	-3616
Amotl2	-3006	-1201	-3090	1353	-4076	734	4186	-1723
Dvl2	-1240	3686	3699	1735	-493	2865	1498	-2983
Lats1	3838	-3699	-4448	-2308	1710	-4236	105	1645
Lats2	-2940	2789	1357	4097	-3895	1540	-2439	-2285
Mob1a	-4494	-2923	-3280	1843	-1793	717	3006	-2323
Mob1b	299	691	588	-2113	-2173	2032	-2919	-1623
Sav1	3436	3026	-4101	4541	-2291	2136	-3890	-4447
Stk4	-3154	798	-539	-1613	-2529	0	-208	-4306
Tjp1	-2201	2176	-259	-959	-3511	528	-2949	-4149
Wwtr1	18	-2967	-1752	-1751	-3959	-3313	-4239	-4576
Yap1	-2486	454	2338	1999	-4608	-3122	-3628	-3896
Ywhab	-4620	470	3016	-1704	-4325	2904	3713	-2102
Ywhae	-1421	1138	3726	878	-2482	2548	3157	-4235

---

---

REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX

REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX

metric	value
setSize	85
pMANOVA	1.08e-30
p.adjustMANOVA	5.66e-29
s.dist	0.803
s.de1	-0.386
s.de2	0.185
s.de3	-0.083
s.de4	-0.202
s.de5	-0.342
s.de6	0.145
s.de7	0.51
s.de8	-0.122
p.de1	3.25e-11
p.de2	0.00232
p.de3	0.198
p.de4	0.00163
p.de5	2.26e-09
p.de6	0.0211
p.de7	5.15e-17
p.de8	0.0329

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning: Removed 2 rows containing non-finite values (stat_ydensity).

Warning: Removed 2 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d7	d1
Rpl12	4489	-4664
Rps4x	4507	-4476
Rps3	4369	-4613
Rplp0	4627	-4122
Rpl8	4596	-4099
Rps3a1	4603	-4063
Rpl3	3954	-4706
Rps9	4416	-4204
Rpl6	4546	-3907
Rps6	3845	-4508
Rps23	4324	-3948
Rps24	4214	-3987
Rpl38	4164	-4020
Rps16	4200	-3928
Rps7	3680	-4463
Rpl14	4686	-3484
Rpsa	4336	-3686
Rpl18a	3690	-4328
Rps25	4421	-3603
Rps18	3582	-4428

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Casc3	2995.0	2633.0	3501.0	888.0	2001.0	-1936.0	3358.0	-832.0
Eif4a3	-3377.0	802.0	3650.0	-2350.0	-3315.0	2942.0	1268.0	-4247.0
Eif4g1	3133.0	596.0	3373.0	-738.0	-445.0	2383.0	1324.0	1366.0
Etf1	4050.0	-336.0	-4019.0	249.0	2138.0	303.0	60.0	2424.0
Magoh	1619.0	-4286.0	-4514.0	-3052.0	95.0	-441.0	-1033.0	-1388.0
Ncbp1	-868.0	-446.0	1598.0	1283.0	-23.0	-1167.0	-975.0	417.0
Ncbp2	3823.0	-2399.0	-2325.0	-3066.0	3393.0	-1910.0	-150.0	-2224.0
Ppp2ca	-2695.0	-4423.0	-3965.0	-4284.0	4294.0	1465.0	2202.0	4300.0
Ppp2r1a	3475.0	793.0	2151.0	-970.0	-526.0	-2201.0	-1661.0	-3985.0
Ppp2r2a	-662.0	4024.0	1083.0	1626.0	-4336.0	765.0	-2710.0	-1137.0
Rnps1	-2968.0	-3253.0	2357.0	2787.0	-1248.0	1117.0	2701.0	1462.0
Rpl10a	-1894.0	3571.0	-3834.0	2405.0	1149.0	1503.0	4350.0	846.0
Rpl11	-4496.0	1016.0	-4540.0	-2626.0	-2907.0	1099.0	752.0	-1922.0
Rpl12	-4664.0	281.0	-448.0	-793.0	-3814.0	4564.0	4489.0	-3529.0
Rpl13	-2756.0	1005.0	1051.0	841.0	611.0	3549.0	4241.0	-1591.0
Rpl14	-3484.0	2450.0	747.0	2965.0	-4204.0	-2832.0	4686.0	850.0
Rpl15	-2333.0	682.0	-2391.0	-1716.0	-434.0	145.0	4528.0	-2820.0
Rpl18	-2246.0	673.0	-464.0	-3786.0	-3107.0	828.0	3782.0	516.0
Rpl18a	-4328.0	2967.0	-1120.0	-1960.0	-1241.0	4412.0	3690.0	-90.0
Rpl19	-1606.0	1822.0	1611.0	-3606.0	-3471.0	-443.0	4499.0	-1853.0
Rpl22	-2109.0	-1577.0	-3978.0	3499.0	-1985.0	1261.0	3149.0	3311.0
Rpl23	-3347.0	-63.0	-2300.0	-4230.0	-2408.0	2686.0	3439.0	-793.0
Rpl23a	-1819.0	-1151.0	-2451.0	-3004.0	-1501.0	-226.0	3929.0	-128.0
Rpl24	2028.0	-1516.0	3293.0	-4019.0	-179.0	-1427.0	4426.0	-3218.0
Rpl26	-3053.0	1295.0	-4458.0	-997.0	-990.0	2647.0	3976.0	1105.0
Rpl27-ps3	1035.5	-4491.5	-977.5	-4204.5	392.5	-3423.5	595.5	97.5
Rpl27a	-765.0	3469.0	-283.0	-562.0	-4092.0	-2771.0	3658.0	-311.0
Rpl28	-3471.0	384.0	-3058.0	-731.0	-2274.0	934.0	3355.0	1698.0
Rpl29	-1550.0	1580.0	3636.0	-1529.0	168.0	618.0	1645.0	-3018.0
Rpl3	-4706.0	641.0	-4117.0	1354.0	-4672.0	-2254.0	3954.0	-3698.0
Rpl30	-4102.0	753.0	-4245.0	2797.0	-2289.0	1925.0	2942.0	2148.0
Rpl32	-2111.0	-114.0	-2493.0	-3242.0	-3875.0	-2355.0	4150.0	758.0
Rpl34	-1902.0	264.0	-2162.0	-2311.0	-3651.0	30.0	809.0	-346.0
Rpl35	-260.0	944.0	1544.0	-3339.0	501.0	1258.0	3955.0	1094.0
Rpl36al	-390.0	-968.0	2202.0	-3883.0	2525.0	3903.0	4182.0	-2045.0
Rpl37	-885.0	-3821.0	2983.0	-4392.0	-150.0	-1608.0	3687.0	-3038.0
Rpl37a	-4109.0	4049.0	548.0	-2516.0	-3379.0	3349.0	1579.0	-738.0
Rpl38	-4020.0	685.0	1227.0	-4372.0	-2807.0	2646.0	4164.0	-2260.0
Rpl39	2029.0	-908.0	-3610.0	-2995.0	-3301.0	-2757.0	633.0	89.0
Rpl3l	4079.0	-1994.0	1273.0	-3652.0	2840.0	-2171.0	-1577.0	500.0
Rpl4	-2436.0	1640.0	704.0	2374.0	-3375.0	2858.0	4681.0	2121.0
Rpl41	-569.0	688.0	-4588.0	-2653.0	-3790.0	-3147.0	3336.0	116.0
Rpl5	-4205.0	3942.0	-4600.0	3080.0	-3141.0	4170.0	2526.0	-272.0
Rpl6	-3907.0	935.0	2495.0	1234.0	-2151.0	2533.0	4546.0	580.0
Rpl8	-4099.0	1539.0	2520.0	676.0	-3408.0	-747.0	4596.0	-1407.0
Rplp0	-4122.0	1684.0	26.0	-47.0	-4420.0	2302.0	4627.0	-2369.0
Rplp1	-401.0	3710.0	-2113.0	-1112.0	-2215.0	1847.0	788.0	-1516.0
Rplp2	-3535.0	2764.0	3261.0	-2224.0	-1456.0	-823.0	2455.0	-2310.0
Rps11	-3099.0	37.0	731.0	-51.0	-3394.0	1460.0	1692.0	-3745.0
Rps12-ps3	-1676.0	NA	-4602.0	-4371.0	666.0	326.0	403.0	NA
Rps13	-3742.0	3659.0	2589.0	2506.0	-2969.0	-1105.0	3084.0	2082.0
Rps14	-2751.0	4064.0	-4050.0	1471.0	-4099.0	1787.0	3924.0	-2801.0
Rps15a	-3365.0	2480.0	-1674.0	-2749.0	-4205.0	-2025.0	3160.0	-125.0
Rps16	-3928.0	417.0	2289.0	1486.0	-4331.0	3460.0	4200.0	-299.0
Rps17	744.0	3046.0	-3851.0	-4065.0	-1359.0	3408.0	2365.0	316.0
Rps18	-4428.0	-2157.0	-657.0	-3732.0	-4029.0	381.0	3582.0	-887.0
Rps19	-1015.0	2899.0	-3396.0	-1095.0	-3824.0	516.0	4356.0	-188.0
Rps20	-3879.0	3874.0	3106.0	367.0	-4671.0	2731.0	3931.0	-2656.0
Rps21	-163.0	1078.0	-567.0	-4304.0	-2536.0	-4229.0	4069.0	-3318.0
Rps23	-3948.0	817.0	-3714.0	-2050.0	-3125.0	1478.0	4324.0	-1081.0
Rps24	-3987.0	195.0	-1883.0	179.0	-3255.0	1024.0	4214.0	-3146.0
Rps25	-3603.0	1296.0	4490.0	-2646.0	-3102.0	134.0	4421.0	-1871.0
Rps26	-3489.0	3699.0	1791.0	-3069.0	-4324.0	3340.0	3518.0	-2951.0
Rps27	-456.0	2984.0	-3857.0	-4315.0	-3723.0	-3843.0	4104.0	-3349.0
Rps27a	-418.0	3577.0	-2139.0	4048.0	-3761.0	-1240.0	2510.0	641.0
Rps29	4695.0	1750.0	4128.0	-4506.0	217.0	-4132.0	2325.0	-2576.0
Rps3	-4613.0	558.0	-1151.0	-1016.0	-4248.0	3067.0	4369.0	1031.0
Rps3a1	-4063.0	1143.0	2961.0	-1734.0	-2087.0	4071.0	4603.0	-889.0
Rps4x	-4476.0	3694.0	2637.0	-2229.0	-3092.0	3557.0	4507.0	-2256.0
Rps5	-2186.0	982.0	-4240.0	-1041.0	-2273.0	2525.0	4238.0	2409.0
Rps6	-4508.0	-1590.0	-3432.0	-837.0	-3496.0	730.0	3845.0	-1317.0
Rps7	-4463.0	-2011.0	-2440.0	910.0	-3663.0	2639.0	3680.0	-2178.0
Rps8	-4062.0	2318.0	3589.0	1616.0	-3146.0	3166.0	2935.0	-3655.0
Rps9	-4204.0	1585.0	3994.0	1252.0	-4213.0	-917.0	4416.0	-2708.0
Rpsa	-3686.0	3186.0	152.0	-1880.0	-2226.0	2889.0	4336.0	270.0
Smg1	-538.0	-3241.0	1148.0	17.0	3368.0	3368.0	-1364.0	4116.0
Smg5	4501.0	1345.0	4106.0	2744.0	-1506.0	-2596.0	15.0	-2607.0
Smg6	-2156.0	3049.0	-2007.0	52.0	-3465.0	-2216.0	-2705.0	-3332.0
Smg7	-3777.0	-3059.0	-3512.0	-1078.0	-1230.0	764.0	-502.0	2646.0
Smg8	-2998.0	2289.0	1680.5	3355.0	-516.0	3724.0	-2291.0	3847.0
Smg9	3342.0	-91.0	-1183.0	206.0	2065.0	-1989.0	667.0	1769.0
Uba52	4621.0	4487.0	1045.0	-3153.0	-367.0	-283.0	1322.0	733.0
Upf2	-1027.0	1628.0	1931.0	1223.0	1313.0	3360.0	530.0	905.0
Upf3a	-2146.0	1869.0	2090.0	4394.0	-1956.0	-1073.0	-367.0	-149.0
Upf3b	-3366.0	131.0	-3408.0	4056.0	3367.0	3151.0	-1270.0	3669.0

---

---

REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

metric	value
setSize	32
pMANOVA	1.02e-09
p.adjustMANOVA	2.18e-08
s.dist	0.802
s.de1	-0.186
s.de2	0.203
s.de3	-0.231
s.de4	0.576
s.de5	-0.252
s.de6	0.215
s.de7	-0.122
s.de8	0.24
p.de1	0.0616
p.de2	0.0418
p.de3	0.0221
p.de4	7.33e-10
p.de5	0.00789
p.de6	0.0349
p.de7	0.197
p.de8	0.0162

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning: Removed 3 rows containing non-finite values (stat_ydensity).

Warning: Removed 3 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d4	d5
Col5a3	4154	-4545
Mmp14	4129	-4261
Col1a1	4684	-3755
Timp2	4253	-4096
Col6a3	4580	-3303
Mmp15	3054	-4503
Col11a2	4409	-2713
Bmp1	4205	-2841
Furin	4183	-2441
Col6a1	4652	-2033
Mmp2	2531	-3364
Col4a2	2228	-3207
Col6a2	4634	-1441
Col1a2	4635	-1269
Pcolce2	3506	-1225
Col3a1	4690	-874
Col4a1	4173	-279
Plod3	410	-1836
P4hb	34	-3202

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Adamts2	3852	-1269	-3742	3125	3886	-1225	3756	3045
Bmp1	-450	-2867	-3883	4205	-2841	-1152	-1740	3710
Col11a2	-1119	3692	441	4409	-2713	2574	-1923	-3064
Col14a1	2304	-3704	-1751	3153	2432	1407	1850	4372
Col15a1	3239	-677	1165	-1804	-3848	-4511	227	1993
Col1a1	-854	4308	-3888	4684	-3755	1713	1693	2196
Col1a2	-2343	4395	-3375	4635	-1269	4560	2000	2607
Col22a1	-2285	-4232	-3555	4591	1931	3558	-3234	3501
Col24a1	-1427	3106	-1664	2823	3342	4045	-1904	-24
Col3a1	-1493	4464	-4596	4690	-874	4309	195	553
Col4a1	-439	2514	-2284	4173	-279	-407	-1794	4364
Col4a2	-1168	2348	1772	2228	-3207	419	-257	4235
Col5a1	957	3237	-837	4511	3234	3353	331	483
Col5a2	-1153	3431	-1707	4673	619	4364	-664	3201
Col5a3	-1390	3916	1023	4154	-4545	1170	-1154	-2241
Col6a1	-2901	3674	-2180	4652	-2033	4487	-4354	2638
Col6a2	-32	834	3312	4634	-1441	3421	-3746	827
Col6a3	628	3975	-2546	4580	-3303	1656	-2717	3435
Col7a1	-2525	4096	4546	4658	3605	3414	3844	-1505
Crtap	-3976	NA	-2619	-1535	-1856	NA	513	NA
Furin	1328	3393	-226	4183	-2441	-1641	-3433	-3677
Mmp14	-3728	3770	-2416	4129	-4261	1354	-354	3017
Mmp15	1172	-1259	237	3054	-4503	-1711	-4458	-3379
Mmp2	-2467	2749	-3407	2531	-3364	1531	-1165	-2393
P4hb	-277	-97	2215	34	-3202	-1057	252	139
Pcolce	619	1030	-2438	3535	824	1156	-556	2229
Pcolce2	-3688	-4359	-2444	3506	-1225	3573	-235	2962
Plod1	-2967	-56	4216	-2600	-1540	-3978	-58	2795
Plod3	-3015	-1157	-2833	410	-1836	-2405	-1599	-836
Ppib	-2399	-4370	-2051	-2239	-1071	-536	1346	-3445
Serpinh1	2735	-3375	3693	-610	-4563	-4560	-840	4000
Timp2	-590	-1182	-3894	4253	-4096	2547	3520	-159

---

---

REACTOME_COLLAGEN_FORMATION

REACTOME_COLLAGEN_FORMATION

metric	value
setSize	27
pMANOVA	1.03e-07
p.adjustMANOVA	1.39e-06
s.dist	0.782
s.de1	-0.184
s.de2	0.182
s.de3	-0.2
s.de4	0.546
s.de5	-0.162
s.de6	0.239
s.de7	-0.0968
s.de8	0.338
p.de1	0.0974
p.de2	0.0943
p.de3	0.0759
p.de4	6.47e-08
p.de5	0.113
p.de6	0.0314
p.de7	0.339
p.de8	0.00183

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning: Removed 3 rows containing non-finite values (stat_ydensity).

Warning: Removed 3 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d4	d8
Col4a1	4173	4364
Col22a1	4591	3501
Col6a3	4580	3435
Bmp1	4205	3710
Col5a2	4673	3201
Col14a1	3153	4372
Col6a1	4652	2638
Col1a2	4635	2607
Pcolce2	3506	2962
Col1a1	4684	2196
Adamts2	3125	3045
Col4a2	2228	4235
Pcolce	3535	2229
Col6a2	4634	827
Col3a1	4690	553
Col5a1	4511	483
P4hb	34	139

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Adamts2	3852	-1269	-3742	3125	3886	-1225	3756	3045
Bmp1	-450	-2867	-3883	4205	-2841	-1152	-1740	3710
Col11a2	-1119	3692	441	4409	-2713	2574	-1923	-3064
Col14a1	2304	-3704	-1751	3153	2432	1407	1850	4372
Col15a1	3239	-677	1165	-1804	-3848	-4511	227	1993
Col1a1	-854	4308	-3888	4684	-3755	1713	1693	2196
Col1a2	-2343	4395	-3375	4635	-1269	4560	2000	2607
Col22a1	-2285	-4232	-3555	4591	1931	3558	-3234	3501
Col24a1	-1427	3106	-1664	2823	3342	4045	-1904	-24
Col3a1	-1493	4464	-4596	4690	-874	4309	195	553
Col4a1	-439	2514	-2284	4173	-279	-407	-1794	4364
Col4a2	-1168	2348	1772	2228	-3207	419	-257	4235
Col5a1	957	3237	-837	4511	3234	3353	331	483
Col5a2	-1153	3431	-1707	4673	619	4364	-664	3201
Col5a3	-1390	3916	1023	4154	-4545	1170	-1154	-2241
Col6a1	-2901	3674	-2180	4652	-2033	4487	-4354	2638
Col6a2	-32	834	3312	4634	-1441	3421	-3746	827
Col6a3	628	3975	-2546	4580	-3303	1656	-2717	3435
Col7a1	-2525	4096	4546	4658	3605	3414	3844	-1505
Crtap	-3976	NA	-2619	-1535	-1856	NA	513	NA
P4hb	-277	-97	2215	34	-3202	-1057	252	139
Pcolce	619	1030	-2438	3535	824	1156	-556	2229
Pcolce2	-3688	-4359	-2444	3506	-1225	3573	-235	2962
Plod1	-2967	-56	4216	-2600	-1540	-3978	-58	2795
Plod3	-3015	-1157	-2833	410	-1836	-2405	-1599	-836
Ppib	-2399	-4370	-2051	-2239	-1071	-536	1346	-3445
Serpinh1	2735	-3375	3693	-610	-4563	-4560	-840	4000

---

---

REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS

REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS

metric	value
setSize	11
pMANOVA	0.00633
p.adjustMANOVA	0.0295
s.dist	0.781
s.de1	-0.399
s.de2	-0.323
s.de3	-0.474
s.de4	-0.161
s.de5	-0.0991
s.de6	-0.25
s.de7	-0.019
s.de8	-0.15
p.de1	0.0423
p.de2	0.0109
p.de3	0.0128
p.de4	0.367
p.de5	0.839
p.de6	0.0749
p.de7	0.994
p.de8	0.579

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning: Removed 1 rows containing non-finite values (stat_ydensity).

Warning: Removed 1 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d3	d1
Plin1	-4532	-4745
Fabp4	-4607	-4446
Lipe	-2443	-4576
Mgll	-4437	-1336
Ppp1cb	-3288	-1546
Cav1	-4398	-577
Ppp1ca	-506	-1608

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Abhd5	2418	-3903	-3976	-752	4551	-2517	-3326	643
Cav1	-577	-4558	-4398	-4288	3737	-3841	2191	-1821
Fabp4	-4446	-4122	-4607	-4457	896	328	-572	-636
Lipe	-4576	-3746	-2443	1905	-3204	-1892	-1975	-1128
Mgll	-1336	-2798	-4437	-1109	416	-3877	3501	1829
Plin1	-4745	4120	-4532	NA	-4659	1315	-1066	-3614
Ppp1ca	-1608	2867	-506	1271	-4066	-2871	3664	828
Ppp1cb	-1546	-4618	-3288	-3650	3152	-219	-2156	2183
Ppp1cc	-574	1819	3246	2022	-3270	452	-475	804
Prkaca	1048	-2905	-2165	1783	134	-2077	-1371	-2979
Prkacb	-4339	545	1821	155	-4720	1518	1347	-4295

---

---

REACTOME_TRANSLATION

REACTOME_TRANSLATION

metric	value
setSize	124
pMANOVA	5.12e-40
p.adjustMANOVA	4.02e-38
s.dist	0.756
s.de1	-0.289
s.de2	0.173
s.de3	-0.0554
s.de4	-0.152
s.de5	-0.241
s.de6	0.236
s.de7	0.551
s.de8	-0.117
p.de1	9.86e-10
p.de2	0.000581
p.de3	0.288
p.de4	0.00436
p.de5	2.14e-07
p.de6	3.67e-06
p.de7	8.98e-28
p.de8	0.0134

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning: Removed 2 rows containing non-finite values (stat_ydensity).

Warning: Removed 2 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d7	d1
Rpl12	4489	-4664
Rps4x	4507	-4476
Rps3	4369	-4613
Rplp0	4627	-4122
Rpl8	4596	-4099
Rps3a1	4603	-4063
Rpl3	3954	-4706
Rps9	4416	-4204
Rpl6	4546	-3907
Rps6	3845	-4508
Rps23	4324	-3948
Eef1a1	3557	-4737
Rps24	4214	-3987
Rpl38	4164	-4020
Rps16	4200	-3928
Rps7	3680	-4463
Rpl14	4686	-3484
Rpsa	4336	-3686
Rpl18a	3690	-4328
Rps25	4421	-3603

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Ddost	753.0	3306.0	317.0	2150.0	-3124.0	800.0	1064.0	-1043.0
Eef1a1	-4737.0	1057.0	-4555.0	4491.0	-4575.0	3799.0	3557.0	-2099.0
Eef1b2	-2430.0	576.0	-1017.0	-2232.0	-3876.0	-1661.0	3260.0	-1113.0
Eef1d	-2772.0	-2404.0	-4007.0	1044.0	-336.0	1976.0	2772.0	3846.0
Eef1g	-246.0	3125.0	2560.0	-2086.0	798.0	3011.0	4696.0	2853.0
Eef2	-2019.0	720.0	1542.0	3786.0	-719.0	4446.0	4592.0	-507.0
Eif1ax	-1642.0	-3794.0	3434.0	-3530.0	-1534.0	1646.0	-831.0	-1285.0
Eif2b1	1491.0	-3058.0	1337.0	844.0	2861.0	-816.0	-763.0	-1184.0
Eif2b2	885.0	3746.0	99.0	-78.0	-1803.0	-118.0	2625.0	-992.0
Eif2b3	864.0	-1856.0	360.0	-2525.0	93.0	3397.0	4726.0	695.0
Eif2b4	2369.0	-65.0	-1942.0	-3119.0	3623.0	318.0	1024.0	200.0
Eif2b5	-3425.0	4165.0	-3853.0	3048.0	152.0	4136.0	-2737.0	-3656.0
Eif2s1	3526.0	2411.0	-449.0	2312.0	-1605.0	-2104.0	-1494.0	-2275.0
Eif2s2	4274.0	2919.0	-270.0	-115.0	3260.0	3954.0	2545.0	-1740.0
Eif2s3x	-2463.0	-702.0	-2901.0	2532.0	2656.0	3291.0	4532.0	2018.0
Eif3a	3198.0	-2833.0	3793.0	-94.0	4338.0	4230.0	3635.0	734.0
Eif3b	-2694.0	1653.0	488.0	1239.0	-570.0	3763.0	3430.0	-1960.0
Eif3c	-358.0	-432.0	3626.0	-1827.0	3983.0	4470.0	3659.0	-1135.0
Eif3d	-826.0	-442.0	2652.0	2681.0	-703.0	1499.0	3386.0	-892.0
Eif3e	-1454.0	-740.0	-3046.0	1714.0	-1910.0	1091.0	4322.0	3080.0
Eif3f	-3228.0	-1711.0	1042.0	550.0	-3130.0	-1119.0	2097.0	-2793.0
Eif3g	-775.0	1101.0	4463.0	-1026.0	3287.0	2971.0	3507.0	-1280.0
Eif3h	-2634.0	-2879.0	-4359.0	3011.0	-1488.0	-356.0	845.0	4143.0
Eif3i	2584.0	2009.0	3804.0	-4111.0	2721.0	758.0	3887.0	-1628.0
Eif3j2	1754.0	-667.0	3932.0	-4529.0	-441.0	3880.0	2557.0	-3819.0
Eif3k	-3419.0	-2381.0	2656.0	648.0	1392.0	547.0	2073.0	2525.0
Eif4a1	445.0	2385.0	1225.0	-2188.0	1097.0	1725.0	1551.0	-3707.0
Eif4a2	816.0	1590.0	1421.0	171.0	2837.0	4208.0	2556.0	3598.0
Eif4b	490.0	-1280.0	4350.0	3628.0	2423.0	4246.0	4737.0	672.0
Eif4e	4242.0	-2550.0	-3253.0	-3029.0	4069.0	-398.0	-1380.0	-541.0
Eif4ebp1	-1375.0	-709.0	-673.0	1009.0	-1921.0	1628.0	4710.0	3871.0
Eif4g1	3133.0	596.0	3373.0	-738.0	-445.0	2383.0	1324.0	1366.0
Eif4h	4115.0	-102.0	-3220.0	-661.0	996.0	-2838.0	3634.0	-2497.0
Eif5	3637.0	1118.0	220.0	1339.0	1848.0	704.0	3661.0	2443.0
Eif5b	1630.0	1634.0	-19.0	-2596.0	2028.0	3703.0	913.0	-2254.0
Etf1	4050.0	-336.0	-4019.0	249.0	2138.0	303.0	60.0	2424.0
Rpl10a	-1894.0	3571.0	-3834.0	2405.0	1149.0	1503.0	4350.0	846.0
Rpl11	-4496.0	1016.0	-4540.0	-2626.0	-2907.0	1099.0	752.0	-1922.0
Rpl12	-4664.0	281.0	-448.0	-793.0	-3814.0	4564.0	4489.0	-3529.0
Rpl13	-2756.0	1005.0	1051.0	841.0	611.0	3549.0	4241.0	-1591.0
Rpl14	-3484.0	2450.0	747.0	2965.0	-4204.0	-2832.0	4686.0	850.0
Rpl15	-2333.0	682.0	-2391.0	-1716.0	-434.0	145.0	4528.0	-2820.0
Rpl18	-2246.0	673.0	-464.0	-3786.0	-3107.0	828.0	3782.0	516.0
Rpl18a	-4328.0	2967.0	-1120.0	-1960.0	-1241.0	4412.0	3690.0	-90.0
Rpl19	-1606.0	1822.0	1611.0	-3606.0	-3471.0	-443.0	4499.0	-1853.0
Rpl22	-2109.0	-1577.0	-3978.0	3499.0	-1985.0	1261.0	3149.0	3311.0
Rpl23	-3347.0	-63.0	-2300.0	-4230.0	-2408.0	2686.0	3439.0	-793.0
Rpl23a	-1819.0	-1151.0	-2451.0	-3004.0	-1501.0	-226.0	3929.0	-128.0
Rpl24	2028.0	-1516.0	3293.0	-4019.0	-179.0	-1427.0	4426.0	-3218.0
Rpl26	-3053.0	1295.0	-4458.0	-997.0	-990.0	2647.0	3976.0	1105.0
Rpl27-ps3	1035.5	-4491.5	-977.5	-4204.5	392.5	-3423.5	595.5	97.5
Rpl27a	-765.0	3469.0	-283.0	-562.0	-4092.0	-2771.0	3658.0	-311.0
Rpl28	-3471.0	384.0	-3058.0	-731.0	-2274.0	934.0	3355.0	1698.0
Rpl29	-1550.0	1580.0	3636.0	-1529.0	168.0	618.0	1645.0	-3018.0
Rpl3	-4706.0	641.0	-4117.0	1354.0	-4672.0	-2254.0	3954.0	-3698.0
Rpl30	-4102.0	753.0	-4245.0	2797.0	-2289.0	1925.0	2942.0	2148.0
Rpl32	-2111.0	-114.0	-2493.0	-3242.0	-3875.0	-2355.0	4150.0	758.0
Rpl34	-1902.0	264.0	-2162.0	-2311.0	-3651.0	30.0	809.0	-346.0
Rpl35	-260.0	944.0	1544.0	-3339.0	501.0	1258.0	3955.0	1094.0
Rpl36al	-390.0	-968.0	2202.0	-3883.0	2525.0	3903.0	4182.0	-2045.0
Rpl37	-885.0	-3821.0	2983.0	-4392.0	-150.0	-1608.0	3687.0	-3038.0
Rpl37a	-4109.0	4049.0	548.0	-2516.0	-3379.0	3349.0	1579.0	-738.0
Rpl38	-4020.0	685.0	1227.0	-4372.0	-2807.0	2646.0	4164.0	-2260.0
Rpl39	2029.0	-908.0	-3610.0	-2995.0	-3301.0	-2757.0	633.0	89.0
Rpl3l	4079.0	-1994.0	1273.0	-3652.0	2840.0	-2171.0	-1577.0	500.0
Rpl4	-2436.0	1640.0	704.0	2374.0	-3375.0	2858.0	4681.0	2121.0
Rpl41	-569.0	688.0	-4588.0	-2653.0	-3790.0	-3147.0	3336.0	116.0
Rpl5	-4205.0	3942.0	-4600.0	3080.0	-3141.0	4170.0	2526.0	-272.0
Rpl6	-3907.0	935.0	2495.0	1234.0	-2151.0	2533.0	4546.0	580.0
Rpl8	-4099.0	1539.0	2520.0	676.0	-3408.0	-747.0	4596.0	-1407.0
Rplp0	-4122.0	1684.0	26.0	-47.0	-4420.0	2302.0	4627.0	-2369.0
Rplp1	-401.0	3710.0	-2113.0	-1112.0	-2215.0	1847.0	788.0	-1516.0
Rplp2	-3535.0	2764.0	3261.0	-2224.0	-1456.0	-823.0	2455.0	-2310.0
Rpn1	4543.0	2819.0	3641.0	-3314.0	-2478.0	-3062.0	3752.0	529.0
Rpn2	-2867.0	2609.0	-2694.0	4526.0	-4632.0	1300.0	4046.0	-1565.0
Rps11	-3099.0	37.0	731.0	-51.0	-3394.0	1460.0	1692.0	-3745.0
Rps12-ps3	-1676.0	NA	-4602.0	-4371.0	666.0	326.0	403.0	NA
Rps13	-3742.0	3659.0	2589.0	2506.0	-2969.0	-1105.0	3084.0	2082.0
Rps14	-2751.0	4064.0	-4050.0	1471.0	-4099.0	1787.0	3924.0	-2801.0
Rps15a	-3365.0	2480.0	-1674.0	-2749.0	-4205.0	-2025.0	3160.0	-125.0
Rps16	-3928.0	417.0	2289.0	1486.0	-4331.0	3460.0	4200.0	-299.0
Rps17	744.0	3046.0	-3851.0	-4065.0	-1359.0	3408.0	2365.0	316.0
Rps18	-4428.0	-2157.0	-657.0	-3732.0	-4029.0	381.0	3582.0	-887.0
Rps19	-1015.0	2899.0	-3396.0	-1095.0	-3824.0	516.0	4356.0	-188.0
Rps20	-3879.0	3874.0	3106.0	367.0	-4671.0	2731.0	3931.0	-2656.0
Rps21	-163.0	1078.0	-567.0	-4304.0	-2536.0	-4229.0	4069.0	-3318.0
Rps23	-3948.0	817.0	-3714.0	-2050.0	-3125.0	1478.0	4324.0	-1081.0
Rps24	-3987.0	195.0	-1883.0	179.0	-3255.0	1024.0	4214.0	-3146.0
Rps25	-3603.0	1296.0	4490.0	-2646.0	-3102.0	134.0	4421.0	-1871.0
Rps26	-3489.0	3699.0	1791.0	-3069.0	-4324.0	3340.0	3518.0	-2951.0
Rps27	-456.0	2984.0	-3857.0	-4315.0	-3723.0	-3843.0	4104.0	-3349.0
Rps27a	-418.0	3577.0	-2139.0	4048.0	-3761.0	-1240.0	2510.0	641.0
Rps29	4695.0	1750.0	4128.0	-4506.0	217.0	-4132.0	2325.0	-2576.0
Rps3	-4613.0	558.0	-1151.0	-1016.0	-4248.0	3067.0	4369.0	1031.0
Rps3a1	-4063.0	1143.0	2961.0	-1734.0	-2087.0	4071.0	4603.0	-889.0
Rps4x	-4476.0	3694.0	2637.0	-2229.0	-3092.0	3557.0	4507.0	-2256.0
Rps5	-2186.0	982.0	-4240.0	-1041.0	-2273.0	2525.0	4238.0	2409.0
Rps6	-4508.0	-1590.0	-3432.0	-837.0	-3496.0	730.0	3845.0	-1317.0
Rps7	-4463.0	-2011.0	-2440.0	910.0	-3663.0	2639.0	3680.0	-2178.0
Rps8	-4062.0	2318.0	3589.0	1616.0	-3146.0	3166.0	2935.0	-3655.0
Rps9	-4204.0	1585.0	3994.0	1252.0	-4213.0	-917.0	4416.0	-2708.0
Rpsa	-3686.0	3186.0	152.0	-1880.0	-2226.0	2889.0	4336.0	270.0
Sec11a	-223.0	4394.0	-871.0	-102.0	-3219.0	2390.0	995.0	499.0
Sec11c	-3718.0	3449.0	1338.0	134.0	-4780.0	1539.0	3973.0	-4485.0
Sec61a1	-4367.0	401.0	-4507.0	3401.0	-3349.0	2877.0	-1764.0	3336.0
Sec61a2	-3733.0	-4190.0	658.0	-3224.0	-712.0	565.0	593.0	-179.0
Sec61b	265.0	3529.0	2667.0	3216.0	-4390.0	-3517.0	1549.0	-3597.0
Sec61g	-4178.0	-239.0	-875.0	-3809.0	2752.0	3673.0	624.0	-1474.0
Spcs1	4097.0	4332.0	-4080.0	3638.0	3487.0	4047.0	1534.0	3094.0
Spcs2	2500.0	-137.0	-2251.0	-1222.0	-1199.0	-1430.0	4011.0	1815.0
Spcs3	-2660.0	-3242.0	443.0	-3459.0	-2189.0	-3255.0	611.0	-1391.0
Srp14	-1428.0	4006.0	-1430.0	2779.0	-4668.0	4107.0	-77.0	-2316.0
Srp19	1749.0	1042.0	-3178.0	-3175.0	1832.0	3384.0	-1608.0	2610.0
Srp54a	4383.0	-3261.0	1565.0	-4189.0	4512.0	-1171.0	866.0	-701.0
Srp68	-2440.0	-3369.0	-565.0	-469.0	1427.0	2188.0	1819.0	-707.0
Srp72	1214.0	2384.0	3516.0	941.0	1515.0	3386.0	4407.0	513.0
Srp9	-2145.0	2556.0	-2789.0	-2380.0	-2677.0	23.0	-520.0	-3090.0
Srprb	-1186.0	-2573.0	3870.0	1808.0	-1273.0	514.0	-294.0	-2651.0
Ssr1	-1599.0	3116.0	3953.0	4180.0	-335.0	93.0	3223.0	1185.0
Ssr2	-3051.0	2641.0	-1318.0	-3354.0	-2502.0	1219.0	2500.0	783.0
Ssr3	4530.0	3601.0	-2712.0	600.0	466.0	1909.0	2058.0	-2918.0
Ssr4	-3331.0	-2538.0	3337.0	-40.0	-174.0	1740.0	4367.0	1289.0
Tram1	-3916.0	-1735.0	-1814.0	3738.0	-1918.0	1873.0	-2596.0	48.0
Uba52	4621.0	4487.0	1045.0	-3153.0	-367.0	-283.0	1322.0	733.0

---

---

REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA

REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA

metric	value
setSize	11
pMANOVA	0.00595
p.adjustMANOVA	0.0283
s.dist	0.751
s.de1	-0.317
s.de2	-0.405
s.de3	-0.163
s.de4	-0.448
s.de5	0.131
s.de6	-0.23
s.de7	-0.0505
s.de8	-0.0157
p.de1	0.0456
p.de2	0.0141
p.de3	0.31
p.de4	0.00733
p.de5	0.514
p.de6	0.152
p.de7	0.76
p.de8	0.9

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d4	d2
Gng5	-4265	-3874
Gnb5	-3207	-4561
Pdpk1	-2420	-4479
Gnb4	-2165	-4494
Gnb1	-3614	-1610
Akt3	-840	-4283
Akt1	-181	-2715

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Akt1	-3454	-2715	-4004	-181	-3346	-1624	-4229	-2326
Akt2	4151	474	849	355	1293	2025	970	1421
Akt3	-3909	-4283	-3522	-840	2682	-215	-232	2781
Gnb1	-788	-1610	2490	-3614	-1786	-4364	1918	-2370
Gnb2	-2386	297	454	-2563	770	-3158	-271	-2637
Gnb4	-3608	-4494	-2203	-2165	2059	-3021	3515	2006
Gnb5	-1125	-4561	197	-3207	4318	-2335	-3	701
Gng11	-1347	704	-946	-472	-2149	-400	-4149	-4205
Gng12	-2886	2876	-2224	-3829	-3648	1903	4321	1808
Gng5	1271	-3874	678	-4265	2596	-1310	-3904	-1132
Pdpk1	-1811	-4479	-435	-2420	2448	-133	143	2925

---

---

REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL

REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL

metric	value
setSize	11
pMANOVA	0.388
p.adjustMANOVA	0.564
s.dist	0.748
s.de1	-0.257
s.de2	0.24
s.de3	-0.327
s.de4	0.241
s.de5	-0.281
s.de6	0.42
s.de7	-0.0937
s.de8	0.0823
p.de1	0.79
p.de2	0.182
p.de3	0.139
p.de4	0.456
p.de5	0.795
p.de6	0.0655
p.de7	0.369
p.de8	0.728

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 4 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 4 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning: Removed 4 rows containing non-finite values (stat_density2d).

Warning: Removed 4 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 4 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning: Removed 5 rows containing non-finite values (stat_density2d).
Removed 5 rows containing non-finite values (stat_density2d).

Warning: Removed 5 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning: Removed 4 rows containing non-finite values (stat_density2d).
Removed 4 rows containing non-finite values (stat_density2d).

Warning: Removed 5 rows containing non-finite values (stat_density2d).

Warning: Removed 4 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 5 rows containing non-finite values (stat_density2d).
Removed 5 rows containing non-finite values (stat_density2d).
Removed 5 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning: Removed 5 rows containing non-finite values (stat_density2d).
Removed 5 rows containing non-finite values (stat_density2d).
Removed 5 rows containing non-finite values (stat_density2d).
Removed 5 rows containing non-finite values (stat_density2d).
Removed 5 rows containing non-finite values (stat_density2d).

Warning: Removed 5 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning: Removed 3 rows containing non-finite values (stat_density2d).

Warning: Removed 5 rows containing non-finite values (stat_density2d).
Removed 5 rows containing non-finite values (stat_density2d).
Removed 5 rows containing non-finite values (stat_density2d).

Warning: Removed 3 rows containing non-finite values (stat_density2d).

Warning: Removed 5 rows containing non-finite values (stat_density2d).

Warning: Removed 3 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning: Removed 5 rows containing non-finite values (stat_density2d).
Removed 5 rows containing non-finite values (stat_density2d).
Removed 5 rows containing non-finite values (stat_density2d).
Removed 5 rows containing non-finite values (stat_density2d).
Removed 5 rows containing non-finite values (stat_density2d).
Removed 5 rows containing non-finite values (stat_density2d).
Removed 5 rows containing non-finite values (stat_density2d).

Warning: Removed 5 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 4 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 4 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning: Removed 4 rows containing missing values (geom_point).

Warning: Removed 4 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 4 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning: Removed 5 rows containing missing values (geom_point).
Removed 5 rows containing missing values (geom_point).

Warning: Removed 5 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning: Removed 4 rows containing missing values (geom_point).
Removed 4 rows containing missing values (geom_point).

Warning: Removed 5 rows containing missing values (geom_point).

Warning: Removed 4 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 5 rows containing missing values (geom_point).
Removed 5 rows containing missing values (geom_point).
Removed 5 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning: Removed 5 rows containing missing values (geom_point).
Removed 5 rows containing missing values (geom_point).
Removed 5 rows containing missing values (geom_point).
Removed 5 rows containing missing values (geom_point).
Removed 5 rows containing missing values (geom_point).

Warning: Removed 5 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning: Removed 3 rows containing missing values (geom_point).

Warning: Removed 5 rows containing missing values (geom_point).
Removed 5 rows containing missing values (geom_point).
Removed 5 rows containing missing values (geom_point).

Warning: Removed 3 rows containing missing values (geom_point).

Warning: Removed 5 rows containing missing values (geom_point).

Warning: Removed 3 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning: Removed 5 rows containing missing values (geom_point).
Removed 5 rows containing missing values (geom_point).
Removed 5 rows containing missing values (geom_point).
Removed 5 rows containing missing values (geom_point).
Removed 5 rows containing missing values (geom_point).
Removed 5 rows containing missing values (geom_point).
Removed 5 rows containing missing values (geom_point).

Warning: Removed 5 rows containing non-finite values (stat_bin).

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning: Removed 27 rows containing non-finite values (stat_ydensity).

Warning: Removed 27 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d6	d3
Itgb1	4021	-4461
B2m	4135	-3363
C3	2832	-4371
Cd34	1199	-3478

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
B2m	-4584	44	-3363	-968	544	4135	2648	-3301
C3	-4245	2892	-4371	4650	-4489	2832	1283	-243
Cd19	-4348	NA	NA	NA	-4768	NA	NA	NA
Cd34	2830	-3933	-3478	2888	3799	1199	-2326	4113
Cd81	-1321	3516	2077	-948	-2435	2215	-522	1709
Fcgr2b	2669	-622	NA	3492	NA	NA	NA	NA
Icam1	-2648	NA	NA	NA	677	NA	-720	NA
Itgb1	3611	1843	-4461	1593	4030	4021	-4490	3073
Pvr	3233	4380	4086	-2036	-3562	-2334	-2128	-3054
Sell	-3170	NA	NA	NA	-4537	NA	NA	NA
Vcam1	-4744	NA	NA	NA	-4467	NA	3178	NA

---

---

REACTOME_G_PROTEIN_ACTIVATION

REACTOME_G_PROTEIN_ACTIVATION

metric	value
setSize	10
pMANOVA	0.00189
p.adjustMANOVA	0.01
s.dist	0.745
s.de1	-0.447
s.de2	-0.278
s.de3	0.0106
s.de4	-0.363
s.de5	-0.0433
s.de6	-0.345
s.de7	0.0151
s.de8	-0.156
p.de1	0.00851
p.de2	0.107
p.de3	0.975
p.de4	0.0388
p.de5	0.723
p.de6	0.0429
p.de7	0.937
p.de8	0.351

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d1	d4
Gng12	-2886	-3829
Gnb4	-3608	-2165
Gnb2	-2386	-2563
Gnai2	-4502	-1261
Gnb5	-1125	-3207
Gnb1	-788	-3614
Gng11	-1347	-472

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Gnai2	-4502	2747	3745	-1261	-4786	-970	3766	-3752
Gnai3	-3113	-1402	-3707	3544	-4499	-3850	-2277	2209
Gnao1	-2302	-4216	2086	877	3442	456	-1479	-367
Gnb1	-788	-1610	2490	-3614	-1786	-4364	1918	-2370
Gnb2	-2386	297	454	-2563	770	-3158	-271	-2637
Gnb4	-3608	-4494	-2203	-2165	2059	-3021	3515	2006
Gnb5	-1125	-4561	197	-3207	4318	-2335	-3	701
Gng11	-1347	704	-946	-472	-2149	-400	-4149	-4205
Gng12	-2886	2876	-2224	-3829	-3648	1903	4321	1808
Gng5	1271	-3874	678	-4265	2596	-1310	-3904	-1132

---

---

REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE

REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE

metric	value
setSize	13
pMANOVA	0.0217
p.adjustMANOVA	0.0786
s.dist	0.744
s.de1	-0.51
s.de2	0.256
s.de3	0.00955
s.de4	0.117
s.de5	-0.433
s.de6	0.117
s.de7	0.0769
s.de8	0.0836
p.de1	0.000679
p.de2	0.0949
p.de3	0.977
p.de4	0.429
p.de5	0.00375
p.de6	0.47
p.de7	0.626
p.de8	0.602

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).
Removed 2867 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d1	d5
Prkcsh	-4354	-4708
Edem1	-4599	-4163
Calr	-4121	-4181
Man1b1	-3891	-4373
Mlec	-2799	-4363
Edem2	-2844	-3598
Mogs	-2621	-3583
Pdia3	-3201	-1382
Ganab	-2153	-1880

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Calr	-4121	1891	1229	527	-4181	2440	2221	1640
Canx	-3644	-2410	3393	-3033	2244	4046	1652	-1462
Edem1	-4599	-682	-710	4321	-4163	-2320	-1007	3388
Edem2	-2844	3215	-1022	1200	-3598	2153	-3174	-713
Edem3	3141	1221	-4484	-3103	-3201	-957	-4292	-2338
Ganab	-2153	1153	-2189	493	-1880	-2537	3923	-1621
Man1b1	-3891	2777	4289	3051	-4373	-218	-116	3160
Mlec	-2799	3880	1434	4367	-4363	268	2348	-4222
Mogs	-2621	4352	-1437	-736	-3583	3928	1337	3641
Pdia3	-3201	-3982	-4469	-1150	-1382	-3861	-1358	1848
Prkcsh	-4354	3836	1286	1622	-4708	2480	1204	-774
Uggt1	-2824	-280	1472	897	1649	3556	2041	-828
Uggt2	2933	1145	1882	-191	2155	-1972	994	3334

---

---

REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR

REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR

metric	value
setSize	10
pMANOVA	0.018
p.adjustMANOVA	0.0662
s.dist	0.742
s.de1	-0.183
s.de2	-0.286
s.de3	-0.232
s.de4	-0.451
s.de5	-0.0789
s.de6	-0.407
s.de7	-0.0736
s.de8	0.00402
p.de1	0.244
p.de2	0.0972
p.de3	0.174
p.de4	0.0101
p.de5	0.58
p.de6	0.0172
p.de7	0.673
p.de8	0.996

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).
Removed 2867 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d4	d6
Gnb1	-3614	-4364
Gnaq	-2714	-3312
Gnb2	-2563	-3158
Gnb5	-3207	-2335
Gnb4	-2165	-3021
Gng5	-4265	-1310
Gng11	-472	-400

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Gna11	1043	-3655	-3584	1570	-3318	-2555	-4407	1195
Gna13	2604	1340	-1771	36	-1027	-1519	718	2855
Gnaq	-743	-963	-4281	-2714	-3226	-3312	-609	1804
Gnb1	-788	-1610	2490	-3614	-1786	-4364	1918	-2370
Gnb2	-2386	297	454	-2563	770	-3158	-271	-2637
Gnb4	-3608	-4494	-2203	-2165	2059	-3021	3515	2006
Gnb5	-1125	-4561	197	-3207	4318	-2335	-3	701
Gng11	-1347	704	-946	-472	-2149	-400	-4149	-4205
Gng12	-2886	2876	-2224	-3829	-3648	1903	4321	1808
Gng5	1271	-3874	678	-4265	2596	-1310	-3904	-1132

---

---

REACTOME_GLUCONEOGENESIS

REACTOME_GLUCONEOGENESIS

metric	value
setSize	20
pMANOVA	7.01e-06
p.adjustMANOVA	5.9e-05
s.dist	0.74
s.de1	0.214
s.de2	0.136
s.de3	0.416
s.de4	-0.23
s.de5	0.264
s.de6	0.31
s.de7	-0.0734
s.de8	-0.296
p.de1	0.0239
p.de2	0.3
p.de3	4.27e-05
p.de4	0.0816
p.de5	0.0194
p.de6	0.0193
p.de7	0.432
p.de8	0.0369

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 2 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 2 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning: Removed 8 rows containing non-finite values (stat_ydensity).

Warning: Removed 8 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d3	d6
Pgk1	4582	4533
Eno3	4609	4313
Gpi1	4613	3857
Pcx	3872	4515
Pfkfb1	3278	4361
Slc25a12	4569	2082
Eno1	1664	4198
Tpi1	3478	1970
Fbp2	1157	4292
Mdh1	1424	3301
Prkacb	1821	1518

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Eno1	-3372	4216	1664	4303	2318	4198	3091	-3795
Eno3	2186	3866	4609	1137	-422	4313	1782	-1164
Fbp2	353	4588	1157	-1995	-3747	4292	1983	-977
Got1	4498	-2992	1249	-4526	4393	-3329	-4227	4046
Got2	3331	-3450	4344	-4454	4161	-1273	-4033	3033
Gpi1	2564	4496	4613	3828	-847	3857	4523	872
Mdh1	4154	-1407	1424	-4527	4453	3301	-4435	2241
Mdh2	3964	-1814	4548	-4216	3980	-551	-4127	-1788
Pck1	-4722	NA	-4048	NA	-4710	NA	-2405	-4280
Pcx	-1604	4439	3872	894	1387	4515	4447	-3791
Pfkfb1	780	-2421	3278	164	4219	4361	503	-180
Pgam1	1726	-1170	1509	163	2972	-1854	1476	-2775
Pgam2	3907	3408	3174	-2929	-1519	-2202	-2854	-3582
Pgk1	1578	4514	4582	-628	1683	4533	847	-2431
Prkaca	1048	-2905	-2165	1783	134	-2077	-1371	-2979
Prkacb	-4339	545	1821	155	-4720	1518	1347	-4295
Slc25a10	-3140	NA	-2394	NA	NA	NA	4404	NA
Slc25a11	2419	-2873	-805	-4302	3499	-1117	-4164	-2597
Slc25a12	2711	-3646	4569	-4232	4160	2082	-1651	-174
Tpi1	4565	4414	3478	558	-94	1970	-852	-2960

---

---

REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING

REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING

metric	value
setSize	18
pMANOVA	0.0101
p.adjustMANOVA	0.0413
s.dist	0.74
s.de1	-0.318
s.de2	-0.207
s.de3	-0.404
s.de4	0.16
s.de5	-0.354
s.de6	-0.275
s.de7	-0.0997
s.de8	-0.0576
p.de1	0.0666
p.de2	0.108
p.de3	0.00452
p.de4	0.399
p.de5	0.0342
p.de6	0.0406
p.de7	0.646
p.de8	0.868

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 2 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning: Removed 5 rows containing non-finite values (stat_ydensity).

Warning: Removed 5 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d3	d5
Csk	-3392	-4820
Grb2	-3912	-4125
Rap1a	-4266	-3476
Akt1	-4004	-3346
Rap1b	-3068	-3224
Ptpn1	-3329	-2264
Bcar1	-3772	-1352
Vwf	-613	-4648
Ptk2	-2297	-1221

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Akt1	-3454	-2715	-4004	-181	-3346	-1624	-4229	-2326
Bcar1	4327	2572	-3772	896	-1352	-3160	-624	-3113
Crk	2911	-1194	-4269	-3577	955	-2656	-4363	-1307
Csk	-4760	-100	-3392	1436	-4820	NA	-1360	-3392
Fn1	3403	-2223	-3487	2710	1060	-3099	-1635	155
Grb2	-3931	-2002	-3912	704	-4125	-1531	2501	-472
Pdpk1	-1811	-4479	-435	-2420	2448	-133	143	2925
Ptk2	3561	-1465	-2297	3441	-1221	-2592	-4428	-1967
Ptpn1	-3863	1735	-3329	2834	-2264	2897	4176	3668
Rap1a	-842	783	-4266	-3007	-3476	-110	-3373	1916
Rap1b	-3816	3359	-3068	3245	-3224	779	3256	1058
Rapgef3	-2268	-1853	1503	-134	-3591	-4606	989	-587
Rasgrp2	-4656	-733	973	1560	-3766	-2311	3503	4419
Shc1	-2680	689	647	4035	-2039	2987	2955	-3293
Sos1	925	-4117	-375	-3693	1777	-2489	3701	684
Syk	-4621	NA	NA	3982	-4797	NA	-2301	NA
Tln1	-1666	-2704	836	2420	2661	-1905	-2638	-3067
Vwf	-2876	-2699	-613	986	-4648	-2244	-3715	-342

---

---

REACTOME_METABOLISM_OF_POLYAMINES

REACTOME_METABOLISM_OF_POLYAMINES

metric	value
setSize	13
pMANOVA	0.0291
p.adjustMANOVA	0.101
s.dist	0.739
s.de1	0.439
s.de2	0.268
s.de3	0.329
s.de4	-0.128
s.de5	0.0603
s.de6	0.107
s.de7	0.344
s.de8	0.155
p.de1	0.0188
p.de2	0.0501
p.de3	0.0511
p.de4	0.63
p.de5	0.923
p.de6	0.379
p.de7	0.0614
p.de8	0.441

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning: Removed 7 rows containing non-finite values (stat_ydensity).

Warning: Removed 7 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d1	d7
Odc1	4611	4695
Sms	4286	4589
Srm	4599	3137
Mtap	4225	2773
Smox	4335	1797
Adi1	1462	4274

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Adi1	1462	2173	4085	306	-3089	-1823	4274	-3561
Amd1	-1017	2705	2995	4216	-1796	3455	152	-4559
Apip	3064	-2273	3924	-462	299	-2406	-650	-972
Enoph1	-1544	3870	-2304	-170	-1820	2656	560	2093
Got1	4498	-2992	1249	-4526	4393	-3329	-4227	4046
Mri1	4037	-1526	4104	2764	3732	-642	-169	2850
Mtap	4225	-1112	119	-3099	2435	-3977	2773	-3066
Odc1	4611	3897	3648	-2517	-594	4359	4695	3472
Paox	362	NA	NA	NA	NA	2330	NA	NA
Sat1	-3992	4253	-764	-759	-3239	4369	3934	3155
Smox	4335	4549	3214	1115	-866	3424	1797	-737
Sms	4286	3838	-2648	-583	737	1744	4589	4105
Srm	4599	-1848	NA	-2936	1424	-3820	3137	1978

---

---

REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE

REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE

metric	value
setSize	10
pMANOVA	0.000902
p.adjustMANOVA	0.00544
s.dist	0.735
s.de1	-0.353
s.de2	-0.26
s.de3	0.00381
s.de4	-0.453
s.de5	0.144
s.de6	-0.318
s.de7	0.0962
s.de8	-0.109
p.de1	0.0353
p.de2	0.132
p.de3	0.994
p.de4	0.00976
p.de5	0.486
p.de6	0.0619
p.de7	0.592
p.de8	0.51

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d4	d1
Gng12	-3829	-2886
Gnb4	-2165	-3608
Gnb2	-2563	-2386
Gnai2	-1261	-4502
Gnb5	-3207	-1125
Gnb1	-3614	-788
Gng11	-472	-1347

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Adcy6	1487	-528	-4037	-827	4598	-2520	1662	4505
Gnai2	-4502	2747	3745	-1261	-4786	-970	3766	-3752
Gnao1	-2302	-4216	2086	877	3442	456	-1479	-367
Gnb1	-788	-1610	2490	-3614	-1786	-4364	1918	-2370
Gnb2	-2386	297	454	-2563	770	-3158	-271	-2637
Gnb4	-3608	-4494	-2203	-2165	2059	-3021	3515	2006
Gnb5	-1125	-4561	197	-3207	4318	-2335	-3	701
Gng11	-1347	704	-946	-472	-2149	-400	-4149	-4205
Gng12	-2886	2876	-2224	-3829	-3648	1903	4321	1808
Gng5	1271	-3874	678	-4265	2596	-1310	-3904	-1132

---

---

REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS

REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS

metric	value
setSize	16
pMANOVA	0.00694
p.adjustMANOVA	0.0314
s.dist	0.716
s.de1	0.0463
s.de2	0.472
s.de3	0.00632
s.de4	0.265
s.de5	-0.301
s.de6	0.135
s.de7	-0.121
s.de8	-0.306
p.de1	0.772
p.de2	0.000316
p.de3	0.736
p.de4	0.0582
p.de5	0.0289
p.de6	0.378
p.de7	0.256
p.de8	0.0427

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning: Removed 1 rows containing non-finite values (stat_ydensity).

Warning: Removed 1 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d2	d8
Grip2	4614	-4314
Camk2a	4035	-2717
Myo6	4244	-2020
Ap2a1	2227	-3535
Ap2s1	3903	-1968
Nsf	4389	-1335
Prkca	2681	-1822
Pick1	2280	-1910
Camk2b	2946	-1393
Mdm2	1873	-1536

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Ap2a1	-2010	2227	137	1512	-3282	-553	1563	-3535
Ap2a2	-3739	-889	159	2142	-2014	1072	417	-3033
Ap2b1	2484	2061	2627	3618	3240	2560	-3790	45
Ap2m1	-1419	-2318	-3968	-926	2296	-531	-2245	3856
Ap2s1	-2396	3903	1231	3503	-2732	-1792	-2750	-1968
Camk2a	2756	4035	-2475	4345	-3151	-1877	1122	-2717
Camk2b	2615	2946	4562	-409	-304	1567	3072	-1393
Camk2d	-3230	2741	356	-1251	-3786	3119	1569	588
Dlg1	2950	2463	3354	-934	-2521	-2129	1071	440
Epb41l1	-1328	-673	-3368	NA	-1876	830	2550	-3352
Grip2	4333	4614	4606	4474	-3691	2875	760	-4314
Mdm2	2429	1873	-135	1484	-4168	-3201	-151	-1536
Myo6	177	4244	-3456	-322	-4599	1745	-3445	-2020
Nsf	-3119	4389	3736	2395	357	4190	-1886	-1335
Pick1	3576	2280	-3340	-1388	1113	-1341	-3456	-1910
Prkca	1012	2681	-3447	2104	-824	3464	-2678	-1822

---

---

REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION

REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION

metric	value
setSize	10
pMANOVA	0.0557
p.adjustMANOVA	0.167
s.dist	0.711
s.de1	-0.237
s.de2	0.0242
s.de3	-0.226
s.de4	-0.129
s.de5	-0.449
s.de6	-0.342
s.de7	-0.215
s.de8	-0.13
p.de1	0.144
p.de2	0.898
p.de3	0.185
p.de4	0.471
p.de5	0.00856
p.de6	0.0445
p.de7	0.223
p.de8	0.432

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d5	d6
Hsp90aa1	-3251	-3962
Plxna2	-3066	-3755
Fyn	-3846	-2982
Pak2	-2738	-2951
Plxna1	-4510	-1158
Rac1	-3113	-250

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Cfl1	-4578	3542	-3434	2494	-4593	1342	-4264	-3893
Fyn	-974	3967	-4289	-2943	-3846	-2982	2358	381
Hsp90aa1	2636	-4071	-2875	-3904	-3251	-3962	-3899	4233
Hsp90ab1	-2163	-210	4295	1531	-3024	1513	2687	3762
Nrp1	-467	-3422	-235	-3651	4112	-3851	-4187	-3116
Pak1	-2175	232	-2650	3767	665	-869	-2007	-4189
Pak2	-3804	-2547	2930	1738	-2738	-2951	1863	-358
Plxna1	1433	3798	175	1272	-4510	-1158	-2543	-4075
Plxna2	2120	-1798	-1776	-2087	-3066	-3755	-4298	-521
Rac1	-2600	1639	-3038	-3801	-3113	-250	4545	1274

---

---

REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION

REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION

metric	value
setSize	22
pMANOVA	0.00112
p.adjustMANOVA	0.0064
s.dist	0.711
s.de1	0.143
s.de2	0.242
s.de3	0.262
s.de4	0.0653
s.de5	0.329
s.de6	0.379
s.de7	0.316
s.de8	0.0447
p.de1	0.335
p.de2	0.0405
p.de3	0.0284
p.de4	0.557
p.de5	0.01
p.de6	0.0015
p.de7	0.00858
p.de8	0.732

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).
Removed 2867 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d6	d5
Eprs	4580	4209
Lars	4513	3857
Aars	3766	3590
Farsb	3616	3302
Rars	4407	2586
Aimp2	3485	2753
Nars	3304	2498
Cars	2014	3587
Sars	1762	3629
Iars	1328	3397
Aimp1	2163	1883
Yars	970	3582
Ppa1	1405	254

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Aars	-1527	-1013	4161	3558	3590	3766	747	-1417
Aimp1	2673	992	-3814	1170	1883	2163	-277	3306
Aimp2	4324	3781	-57	-2212	2753	3485	2559	-4113
Cars	2072	4210	-3898	1742	3587	2014	-2199	2092
Dars	4056	-744	-3403	-3320	3400	-965	945	-984
Eprs	1418	3011	4340	-3945	4209	4580	4693	4381
Farsa	-881	128	4595	4606	-3445	-2306	3675	-4212
Farsb	-1103	-872	3065	-3609	3302	3616	4283	2355
Gars	334	3814	2292	3797	-1961	1580	841	-1776
Hars	1967	-110	-3694	2706	-674	-1840	-2991	3409
Iars	201	-482	4324	1568	3397	1328	3927	3066
Kars	4567	1909	4353	2582	3103	-1614	3263	431
Lars	531	2269	-2168	-874	3857	4513	3182	-548
Nars	2193	1769	2110	-113	2498	3304	361	-1241
Ppa1	25	-186	226	1113	254	1405	-4176	2193
Qars	-1677	3809	1234	3111	-2827	3240	783	-3272
Rars	-3960	1734	3645	-3017	2586	4407	4574	-200
Sars	2089	-2413	3996	2567	3629	1762	907	-1645
Tars	-2159	3799	2414	-3452	-917	4514	1082	-300
Vars	-2786	3411	2665	559	-3523	744	3848	-772
Wars	2923	-1223	662	2174	-630	-867	2624	2284
Yars	2079	-1884	1081	-2250	3582	970	2569	1359

---

---

REACTOME_SIGNAL_AMPLIFICATION

REACTOME_SIGNAL_AMPLIFICATION

metric	value
setSize	14
pMANOVA	0.00116
p.adjustMANOVA	0.0064
s.dist	0.707
s.de1	-0.326
s.de2	-0.272
s.de3	-0.147
s.de4	-0.362
s.de5	-0.14
s.de6	-0.371
s.de7	-0.0915
s.de8	-0.0215
p.de1	0.0206
p.de2	0.0621
p.de3	0.301
p.de4	0.0147
p.de5	0.287
p.de6	0.01
p.de7	0.536
p.de8	0.856

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).
Removed 2867 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d6	d4
Gnb1	-4364	-3614
Gnaq	-3312	-2714
Gnb2	-3158	-2563
Gnb5	-2335	-3207
Gnb4	-3021	-2165
Gng5	-1310	-4265
Gnai2	-970	-1261
Mapk14	-2513	-273
Gng11	-400	-472

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Gna11	1043	-3655	-3584	1570	-3318	-2555	-4407	1195
Gna13	2604	1340	-1771	36	-1027	-1519	718	2855
Gnai2	-4502	2747	3745	-1261	-4786	-970	3766	-3752
Gnai3	-3113	-1402	-3707	3544	-4499	-3850	-2277	2209
Gnaq	-743	-963	-4281	-2714	-3226	-3312	-609	1804
Gnb1	-788	-1610	2490	-3614	-1786	-4364	1918	-2370
Gnb2	-2386	297	454	-2563	770	-3158	-271	-2637
Gnb4	-3608	-4494	-2203	-2165	2059	-3021	3515	2006
Gnb5	-1125	-4561	197	-3207	4318	-2335	-3	701
Gng11	-1347	704	-946	-472	-2149	-400	-4149	-4205
Gng12	-2886	2876	-2224	-3829	-3648	1903	4321	1808
Gng5	1271	-3874	678	-4265	2596	-1310	-3904	-1132
Mapk14	-1738	-1864	3709	-273	-1451	-2513	-1366	-1401
P2ry1	-3522	-4086	-2489	-4456	4387	1753	-2487	1221

---

---

REACTOME_STRIATED_MUSCLE_CONTRACTION

REACTOME_STRIATED_MUSCLE_CONTRACTION

metric	value
setSize	22
pMANOVA	0.000295
p.adjustMANOVA	0.00199
s.dist	0.705
s.de1	0.363
s.de2	-0.249
s.de3	0.0104
s.de4	-0.312
s.de5	0.306
s.de6	0.155
s.de7	-0.0317
s.de8	0.295
p.de1	0.00555
p.de2	0.0322
p.de3	0.964
p.de4	0.00865
p.de5	0.0171
p.de6	0.207
p.de7	0.784
p.de8	0.0125

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).
Removed 2867 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d1	d4
Mybpc1	4951	-4510
Tcap	4843	-4172
Actn2	3822	-4443
Tpm2	3747	-4519
Myl2	3277	-4416
Tnni2	3372	-3580
Tnnc2	3144	-3043
Tnnt1	2012	-4500
Myl3	1926	-4561

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Actn2	3822	-3777	-3734	-4443	4051	-1574	-4259	3523
Des	3471	-1078	4022	2043	1625	1629	4388	3026
Dmd	4739	398	1787	3006	1982	2475	-3359	3766
Mybpc1	4951	-4470	-3429	-4510	4427	-3690	-3934	2862
Mybpc2	-725	3728	4631	3405	-2019	4508	4732	2685
Myl1	3651	3028	2469	1503	-257	3241	3560	-202
Myl2	3277	-4631	-4275	-4416	3239	-982	-4254	2939
Myl3	1926	-4633	-4452	-4561	2688	-1632	-4175	2425
Myl4	699	4433	2583	1569	3202	4450	2756	-230
Neb	4138	-1819	3939	3329	4251	3730	1026	4165
Tcap	4843	-3413	4013	-4172	3154	-567	3144	1631
Tmod1	2465	-1631	4245	3658	-1034	127	2752	44
Tnnc1	-494	-4576	-4631	-4548	-61	-446	-3940	370
Tnnc2	3144	3442	4567	-3043	846	3689	3695	-3188
Tnni1	-166	-3472	-4632	-4381	21	-1064	-3903	1235
Tnni2	3372	870	4425	-3580	874	2773	3930	-2261
Tnnt1	2012	-4453	-4623	-4500	1005	-2030	-4148	650
Tpm1	2277	3840	4520	663	-1960	3839	4114	-3133
Tpm2	3747	-4628	2644	-4519	4114	-3069	-3857	895
Tpm3	-2128	-4399	-4614	-4460	-355	-1543	-3703	2255
Tpm4	-3619	-1999	-3728	-3697	-1295	-1791	1835	3474
Vim	-4606	2566	-4493	3885	723	3803	1771	4189

---

---

REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS

REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS

metric	value
setSize	22
pMANOVA	0.0268
p.adjustMANOVA	0.0947
s.dist	0.696
s.de1	-0.535
s.de2	-0.245
s.de3	-0.149
s.de4	0.0823
s.de5	-0.256
s.de6	-0.0191
s.de7	0.141
s.de8	-0.153
p.de1	0.0112
p.de2	0.0328
p.de3	0.279
p.de4	0.79
p.de5	0.997
p.de6	0.668
p.de7	0.387
p.de8	0.262

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 6 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 6 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 6 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 4 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning: Removed 6 rows containing non-finite values (stat_density2d).

Warning: Removed 6 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 6 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 6 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 6 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning: Removed 7 rows containing non-finite values (stat_density2d).
Removed 7 rows containing non-finite values (stat_density2d).

Warning: Removed 7 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning: Removed 6 rows containing non-finite values (stat_density2d).

Warning: Removed 7 rows containing non-finite values (stat_density2d).
Removed 7 rows containing non-finite values (stat_density2d).

Warning: Removed 6 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 6 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 6 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 6 rows containing non-finite values (stat_density2d).

Warning: Removed 7 rows containing non-finite values (stat_density2d).

Warning: Removed 6 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 6 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 4 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning: Removed 6 rows containing non-finite values (stat_density2d).
Removed 6 rows containing non-finite values (stat_density2d).

Warning: Removed 7 rows containing non-finite values (stat_density2d).
Removed 7 rows containing non-finite values (stat_density2d).

Warning: Removed 6 rows containing non-finite values (stat_density2d).

Warning: Removed 6 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 6 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning: Removed 4 rows containing non-finite values (stat_density2d).

Warning: Removed 6 rows containing non-finite values (stat_density2d).

Warning: Removed 7 rows containing non-finite values (stat_density2d).

Warning: Removed 6 rows containing non-finite values (stat_density2d).

Warning: Removed 4 rows containing non-finite values (stat_density2d).

Warning: Removed 6 rows containing non-finite values (stat_density2d).

Warning: Removed 4 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning: Removed 7 rows containing non-finite values (stat_density2d).
Removed 7 rows containing non-finite values (stat_density2d).
Removed 7 rows containing non-finite values (stat_density2d).
Removed 7 rows containing non-finite values (stat_density2d).
Removed 7 rows containing non-finite values (stat_density2d).
Removed 7 rows containing non-finite values (stat_density2d).
Removed 7 rows containing non-finite values (stat_density2d).

Warning: Removed 7 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 6 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 6 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 6 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 4 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning: Removed 6 rows containing missing values (geom_point).

Warning: Removed 6 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 6 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 6 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 6 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning: Removed 7 rows containing missing values (geom_point).
Removed 7 rows containing missing values (geom_point).

Warning: Removed 7 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning: Removed 6 rows containing missing values (geom_point).

Warning: Removed 7 rows containing missing values (geom_point).
Removed 7 rows containing missing values (geom_point).

Warning: Removed 6 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 6 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 6 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 6 rows containing missing values (geom_point).

Warning: Removed 7 rows containing missing values (geom_point).

Warning: Removed 6 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 6 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 4 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning: Removed 6 rows containing missing values (geom_point).
Removed 6 rows containing missing values (geom_point).

Warning: Removed 7 rows containing missing values (geom_point).
Removed 7 rows containing missing values (geom_point).

Warning: Removed 6 rows containing missing values (geom_point).

Warning: Removed 6 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 6 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning: Removed 4 rows containing missing values (geom_point).

Warning: Removed 6 rows containing missing values (geom_point).

Warning: Removed 7 rows containing missing values (geom_point).

Warning: Removed 6 rows containing missing values (geom_point).

Warning: Removed 4 rows containing missing values (geom_point).

Warning: Removed 6 rows containing missing values (geom_point).

Warning: Removed 4 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning: Removed 7 rows containing missing values (geom_point).
Removed 7 rows containing missing values (geom_point).
Removed 7 rows containing missing values (geom_point).
Removed 7 rows containing missing values (geom_point).
Removed 7 rows containing missing values (geom_point).
Removed 7 rows containing missing values (geom_point).
Removed 7 rows containing missing values (geom_point).

Warning: Removed 7 rows containing non-finite values (stat_bin).

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning: Removed 37 rows containing non-finite values (stat_ydensity).

Warning: Removed 37 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d1	d5
Syk	-4621	-4797
Pik3cd	-4637	-4761
Cd79b	-4585	-4739
Itpr3	-4597	-4686
Cd19	-4348	-4768
Cd79a	-4274	-4767
Lyn	-4120	-4725
Cbl	-4268	-4471
Plcg1	-4039	-4643
Grb2	-3931	-4125
Shc1	-2680	-2039
Fyn	-974	-3846

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Calm1	468	-3493	4625	3725	-622	-188	2394	-2143
Cbl	-4268	2459	-4017	28	-4471	-1549	-765	-2509
Cblb	2502	2696	-3992	4651	1520	2246	952	3814
Cd19	-4348	NA	NA	NA	-4768	NA	NA	NA
Cd79a	-4274	NA	NA	NA	-4767	NA	NA	NA
Cd79b	-4585	NA	NA	NA	-4739	NA	NA	NA
Fyn	-974	3967	-4289	-2943	-3846	-2982	2358	381
Grb2	-3931	-2002	-3912	704	-4125	-1531	2501	-472
Itpr2	-1147	-3046	2428	581	4065	-3729	-1883	818
Itpr3	-4597	NA	NA	NA	-4686	NA	2945	NA
Lyn	-4120	2875	NA	NA	-4725	2425	2689	NA
Nck1	-3682	-3039	-2713	-878	1792	2424	-2667	-884
Orai1	1711	950	3186	3402	4227	4051	844	-2128
Pik3ap1	-4658	NA	NA	NA	NA	NA	NA	NA
Pik3cd	-4637	-4155	3420	-501	-4761	-99	2917	-1767
Pik3r1	-4097	-3036	-3900	-944	4425	4567	3401	3727
Plcg1	-4039	-1307	-3138	1255	-4643	-3932	-1221	-134
Sh3kbp1	-2085	-4278	2530	-3969	4043	-1247	-691	-4081
Shc1	-2680	689	647	4035	-2039	2987	2955	-3293
Sos1	925	-4117	-375	-3693	1777	-2489	3701	684
Stim1	2117	-4257	-1253	-1952	1772	-2910	-4529	-3393
Syk	-4621	NA	NA	3982	-4797	NA	-2301	NA

---

---

REACTOME_INTERFERON_GAMMA_SIGNALING

REACTOME_INTERFERON_GAMMA_SIGNALING

metric	value
setSize	32
pMANOVA	0.00292
p.adjustMANOVA	0.0146
s.dist	0.694
s.de1	-0.383
s.de2	0.359
s.de3	0.0634
s.de4	0.159
s.de5	-0.207
s.de6	0.233
s.de7	0.113
s.de8	-0.26
p.de1	0.00378
p.de2	0.00124
p.de3	0.518
p.de4	0.279
p.de5	0.294
p.de6	0.0109
p.de7	0.268
p.de8	0.0256

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 8 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 8 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 8 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 8 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 11 rows containing missing values

Warning: Removed 8 rows containing non-finite values (stat_density2d).

Warning: Removed 8 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 8 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 9 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 8 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 9 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 9 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 11 rows containing missing values

Warning: Removed 8 rows containing non-finite values (stat_density2d).
Removed 8 rows containing non-finite values (stat_density2d).

Warning: Removed 8 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 9 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 8 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 9 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 9 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 11 rows containing missing values

Warning: Removed 8 rows containing non-finite values (stat_density2d).

Warning: Removed 9 rows containing non-finite values (stat_density2d).
Removed 9 rows containing non-finite values (stat_density2d).

Warning: Removed 8 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 8 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 8 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 10 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 11 rows containing missing values

Warning: Removed 3 rows containing non-finite values (stat_density2d).

Warning: Removed 8 rows containing non-finite values (stat_density2d).
Removed 8 rows containing non-finite values (stat_density2d).
Removed 8 rows containing non-finite values (stat_density2d).

Warning: Removed 3 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 8 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 11 rows containing missing values

Warning: Removed 8 rows containing non-finite values (stat_density2d).

Warning: Removed 9 rows containing non-finite values (stat_density2d).
Removed 9 rows containing non-finite values (stat_density2d).

Warning: Removed 8 rows containing non-finite values (stat_density2d).
Removed 8 rows containing non-finite values (stat_density2d).

Warning: Removed 8 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 10 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 11 rows containing missing values

Warning: Removed 7 rows containing non-finite values (stat_density2d).

Warning: Removed 9 rows containing non-finite values (stat_density2d).
Removed 9 rows containing non-finite values (stat_density2d).

Warning: Removed 10 rows containing non-finite values (stat_density2d).

Warning: Removed 7 rows containing non-finite values (stat_density2d).

Warning: Removed 10 rows containing non-finite values (stat_density2d).

Warning: Removed 7 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 11 rows containing missing values

Warning: Removed 11 rows containing non-finite values (stat_density2d).
Removed 11 rows containing non-finite values (stat_density2d).
Removed 11 rows containing non-finite values (stat_density2d).
Removed 11 rows containing non-finite values (stat_density2d).
Removed 11 rows containing non-finite values (stat_density2d).
Removed 11 rows containing non-finite values (stat_density2d).
Removed 11 rows containing non-finite values (stat_density2d).

Warning: Removed 11 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 8 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 8 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 8 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 8 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 11 rows containing missing values

Warning: Removed 8 rows containing missing values (geom_point).

Warning: Removed 8 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 8 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 9 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 8 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 9 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 9 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 11 rows containing missing values

Warning: Removed 8 rows containing missing values (geom_point).
Removed 8 rows containing missing values (geom_point).

Warning: Removed 8 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 9 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 8 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 9 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 9 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 11 rows containing missing values

Warning: Removed 8 rows containing missing values (geom_point).

Warning: Removed 9 rows containing missing values (geom_point).
Removed 9 rows containing missing values (geom_point).

Warning: Removed 8 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 8 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 8 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 10 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 11 rows containing missing values

Warning: Removed 3 rows containing missing values (geom_point).

Warning: Removed 8 rows containing missing values (geom_point).
Removed 8 rows containing missing values (geom_point).
Removed 8 rows containing missing values (geom_point).

Warning: Removed 3 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 8 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 7 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 11 rows containing missing values

Warning: Removed 8 rows containing missing values (geom_point).

Warning: Removed 9 rows containing missing values (geom_point).
Removed 9 rows containing missing values (geom_point).

Warning: Removed 8 rows containing missing values (geom_point).
Removed 8 rows containing missing values (geom_point).

Warning: Removed 8 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 10 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 11 rows containing missing values

Warning: Removed 7 rows containing missing values (geom_point).

Warning: Removed 9 rows containing missing values (geom_point).
Removed 9 rows containing missing values (geom_point).

Warning: Removed 10 rows containing missing values (geom_point).

Warning: Removed 7 rows containing missing values (geom_point).

Warning: Removed 10 rows containing missing values (geom_point).

Warning: Removed 7 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 11 rows containing missing values

Warning: Removed 11 rows containing missing values (geom_point).
Removed 11 rows containing missing values (geom_point).
Removed 11 rows containing missing values (geom_point).
Removed 11 rows containing missing values (geom_point).
Removed 11 rows containing missing values (geom_point).
Removed 11 rows containing missing values (geom_point).
Removed 11 rows containing missing values (geom_point).

Warning: Removed 11 rows containing non-finite values (stat_bin).

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning: Removed 53 rows containing non-finite values (stat_ydensity).

Warning: Removed 53 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d1	d2
H2-Aa	-4684	4605
H2-Eb1	-4708	4501
Prkcd	-4338	4537
Irf9	-4402	4398
Ptpn2	-2127	4424
Camk2d	-3230	2741
Ptpn1	-3863	1735
Irf8	-4655	1178
Gbp7	-3132	1430
Ifngr1	-2719	1020
Irf2	-982	1701
Sumo1	-168	3594
B2m	-4584	44

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
B2m	-4584	44.0	-3363.0	-968	544	4135	2648	-3301
Camk2a	2756	4035.0	-2475.0	4345	-3151	-1877	1122	-2717
Camk2b	2615	2946.0	4562.0	-409	-304	1567	3072	-1393
Camk2d	-3230	2741.0	356.0	-1251	-3786	3119	1569	588
Cd44	3557	-2142.5	2022.0	4543	-2940	-3924	NA	NA
Ciita	-4738	NA	NA	NA	NA	NA	NA	NA
Gbp7	-3132	1430.0	-2265.0	1479	4438	4585	-3962	-3927
H2-Aa	-4684	4605.0	-1939.0	3243	-4266	4469	-4282	-4468
H2-Eb1	-4708	4501.0	2002.0	2230	-3506	4597	-4060	-4436
Icam1	-2648	NA	NA	NA	677	NA	-720	NA
Ifngr1	-2719	1020.0	1425.0	2139	-748	1132	1945	4175
Ifngr2	-1958	-1187.0	0.0	-2190	-1551	1334	4222	57
Irf1	238	-2892.0	1966.0	-2919	3757	151	4032	-4135
Irf2	-982	1701.0	816.0	640	-2348	-992	-188	-720
Irf3	3459	4506.0	-2425.0	929	-798	-4000	2264	-718
Irf5	-3755	-159.0	-505.0	NA	3585	NA	-1825	NA
Irf7	-2990	NA	NA	NA	NA	NA	NA	NA
Irf8	-4655	1178.0	2835.0	4528	-4875	-2192	-3675	-4475
Irf9	-4402	4398.0	-2557.0	-3395	-1483	3756	-561	NA
Jak1	1030	2277.0	3508.0	3041	4062	4495	4435	3735
Jak2	4815	1892.0	4040.0	-510	4191	2071	4769	4574
Pias1	-1457	-3372.0	1949.0	-1074	-2595	-1959	3465	-3664
Pml	-4485	NA	NA	NA	-4894	NA	NA	NA
Prkcd	-4338	4537.0	3014.0	4613	-1672	2828	-2716	-3193
Ptpn1	-3863	1735.0	-3329.0	2834	-2264	2897	4176	3668
Ptpn2	-2127	4424.0	2457.5	352	-1805	1041	546	-2897
Ptpn6	-4695	NA	NA	NA	-4827	NA	NA	NA
Socs1	-307	NA	NA	NA	NA	NA	NA	NA
Socs3	4859	NA	NA	4636	-4858	-4634	NA	NA
Stat1	-4322	-185.0	-1291.0	-4229	3631	21	-1028	-4418
Sumo1	-168	3594.0	-3298.0	-2512	-1406	3783	-2939	772
Vcam1	-4744	NA	NA	NA	-4467	NA	3178	NA

---

---

REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION

REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION

metric	value
setSize	19
pMANOVA	0.0183
p.adjustMANOVA	0.0666
s.dist	0.689
s.de1	-0.28
s.de2	-0.224
s.de3	-0.399
s.de4	0.131
s.de5	-0.291
s.de6	-0.264
s.de7	-0.125
s.de8	-0.0187
p.de1	0.106
p.de2	0.0743
p.de3	0.00385
p.de4	0.518
p.de5	0.0893
p.de6	0.0422
p.de7	0.486
p.de8	0.902

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 2 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning: Removed 5 rows containing non-finite values (stat_ydensity).

Warning: Removed 5 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d3	d5
Csk	-3392	-4820
Grb2	-3912	-4125
Rap1a	-4266	-3476
Akt1	-4004	-3346
Rap1b	-3068	-3224
Ptpn1	-3329	-2264
Bcar1	-3772	-1352
Vwf	-613	-4648
Ptk2	-2297	-1221

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Akt1	-3454	-2715	-4004	-181	-3346	-1624	-4229	-2326
Bcar1	4327	2572	-3772	896	-1352	-3160	-624	-3113
Crk	2911	-1194	-4269	-3577	955	-2656	-4363	-1307
Csk	-4760	-100	-3392	1436	-4820	NA	-1360	-3392
Fn1	3403	-2223	-3487	2710	1060	-3099	-1635	155
Grb2	-3931	-2002	-3912	704	-4125	-1531	2501	-472
Pdpk1	-1811	-4479	-435	-2420	2448	-133	143	2925
Ptk2	3561	-1465	-2297	3441	-1221	-2592	-4428	-1967
Ptpn1	-3863	1735	-3329	2834	-2264	2897	4176	3668
Rap1a	-842	783	-4266	-3007	-3476	-110	-3373	1916
Rap1b	-3816	3359	-3068	3245	-3224	779	3256	1058
Rapgef3	-2268	-1853	1503	-134	-3591	-4606	989	-587
Rasgrp2	-4656	-733	973	1560	-3766	-2311	3503	4419
Shc1	-2680	689	647	4035	-2039	2987	2955	-3293
Sos1	925	-4117	-375	-3693	1777	-2489	3701	684
Syk	-4621	NA	NA	3982	-4797	NA	-2301	NA
Thpo	2100	-2492	-1467	-1843	3938	-483	-2752	3106
Tln1	-1666	-2704	836	2420	2661	-1905	-2638	-3067
Vwf	-2876	-2699	-613	986	-4648	-2244	-3715	-342

---

---

REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING

REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING

metric	value
setSize	12
pMANOVA	0.0176
p.adjustMANOVA	0.0654
s.dist	0.682
s.de1	-0.255
s.de2	-0.375
s.de3	-0.198
s.de4	-0.376
s.de5	0.14
s.de6	-0.219
s.de7	-0.0898
s.de8	-0.0561
p.de1	0.0868
p.de2	0.0176
p.de3	0.201
p.de4	0.019
p.de5	0.459
p.de6	0.155
p.de7	0.575
p.de8	0.698

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d4	d2
Gng5	-4265	-3874
Gnb5	-3207	-4561
Pdpk1	-2420	-4479
Gnb4	-2165	-4494
Gnb1	-3614	-1610
Akt3	-840	-4283
Akt1	-181	-2715

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Akt1	-3454	-2715	-4004	-181	-3346	-1624	-4229	-2326
Akt2	4151	474	849	355	1293	2025	970	1421
Akt3	-3909	-4283	-3522	-840	2682	-215	-232	2781
Gnb1	-788	-1610	2490	-3614	-1786	-4364	1918	-2370
Gnb2	-2386	297	454	-2563	770	-3158	-271	-2637
Gnb4	-3608	-4494	-2203	-2165	2059	-3021	3515	2006
Gnb5	-1125	-4561	197	-3207	4318	-2335	-3	701
Gng11	-1347	704	-946	-472	-2149	-400	-4149	-4205
Gng12	-2886	2876	-2224	-3829	-3648	1903	4321	1808
Gng5	1271	-3874	678	-4265	2596	-1310	-3904	-1132
Pdpk1	-1811	-4479	-435	-2420	2448	-133	143	2925
Plcb3	2150	-212	-2821	2102	1035	-485	-2463	-2443

---

---

REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS

REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS

metric	value
setSize	20
pMANOVA	0.0531
p.adjustMANOVA	0.164
s.dist	0.667
s.de1	-0.00264
s.de2	-0.202
s.de3	-0.347
s.de4	-0.0565
s.de5	-0.0623
s.de6	-0.427
s.de7	-0.287
s.de8	0.11
p.de1	0.991
p.de2	0.143
p.de3	0.0137
p.de4	0.897
p.de5	0.79
p.de6	0.00821
p.de7	0.0266
p.de8	0.337

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 4 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 4 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 3 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 4 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 4 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning: Removed 3 rows containing non-finite values (stat_density2d).
Removed 3 rows containing non-finite values (stat_density2d).

Warning: Removed 4 rows containing non-finite values (stat_density2d).

Warning: Removed 3 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 4 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 3 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 4 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning: Removed 4 rows containing non-finite values (stat_density2d).
Removed 4 rows containing non-finite values (stat_density2d).

Warning: Removed 5 rows containing non-finite values (stat_density2d).
Removed 5 rows containing non-finite values (stat_density2d).

Warning: Removed 4 rows containing non-finite values (stat_density2d).

Warning: Removed 4 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 4 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 6 rows containing missing values

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 3 rows containing non-finite values (stat_density2d).

Warning: Removed 4 rows containing non-finite values (stat_density2d).
Removed 4 rows containing non-finite values (stat_density2d).

Warning: Removed 3 rows containing non-finite values (stat_density2d).

Warning: Removed 4 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning: Removed 5 rows containing non-finite values (stat_density2d).
Removed 5 rows containing non-finite values (stat_density2d).
Removed 5 rows containing non-finite values (stat_density2d).
Removed 5 rows containing non-finite values (stat_density2d).
Removed 5 rows containing non-finite values (stat_density2d).

Warning: Removed 6 rows containing non-finite values (stat_density2d).

Warning: Removed 5 rows containing non-finite values (stat_density2d).

Warning: Removed 5 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 4 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 4 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 3 rows containing missing values (geom_point).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 4 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 4 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning: Removed 3 rows containing missing values (geom_point).
Removed 3 rows containing missing values (geom_point).

Warning: Removed 4 rows containing missing values (geom_point).

Warning: Removed 3 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 4 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).

Warning: Removed 3 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 4 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning: Removed 4 rows containing missing values (geom_point).
Removed 4 rows containing missing values (geom_point).

Warning: Removed 5 rows containing missing values (geom_point).
Removed 5 rows containing missing values (geom_point).

Warning: Removed 4 rows containing missing values (geom_point).

Warning: Removed 4 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 4 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 6 rows containing missing values

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 3 rows containing missing values (geom_point).

Warning: Removed 4 rows containing missing values (geom_point).
Removed 4 rows containing missing values (geom_point).

Warning: Removed 3 rows containing missing values (geom_point).

Warning: Removed 4 rows containing missing values (geom_point).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 5 rows containing missing values

Warning: Removed 5 rows containing missing values (geom_point).
Removed 5 rows containing missing values (geom_point).
Removed 5 rows containing missing values (geom_point).
Removed 5 rows containing missing values (geom_point).
Removed 5 rows containing missing values (geom_point).

Warning: Removed 6 rows containing missing values (geom_point).

Warning: Removed 5 rows containing missing values (geom_point).

Warning: Removed 5 rows containing non-finite values (stat_bin).

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning: Removed 19 rows containing non-finite values (stat_ydensity).

Warning: Removed 19 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d6	d3
S1pr1	-4646	-3998
Lpar1	-4520	-4086
Aplnr	-4251	-3725
Ednrb	-3580	-3382
Adrb2	-2360	-3197
Ccl25	-2640	-1830
Anxa1	-759	-4433
Agt	-2986	-996
Ccl11	-449	-740

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Adrb2	1698	4293	-3197	1431	-4435	-2360	-3357	-3238
Agt	4592	-2189	-996	-995	1799	-2986	-1666	290
Anxa1	-583	-1605	-4433	942	-953	-759	4237	3852
Aplnr	4908	-1985	-3725	NA	643	-4251	-3916	NA
App	-2632	816	542	2786	873	1276	-2894	1165
C3	-4245	2892	-4371	4650	-4489	2832	1283	-243
Ccl11	244	-1061	-740	-266	3325	-449	-2920	4022
Ccl25	3763	-946	-1830	3908	-1211	-2640	-358	2137
Ccl27a	-3075	901	425	-1507	-2077	-2315	-452	-1056
Ccr2	-4505	4313	-25	-3607	-3683	NA	NA	NA
Cxcl12	-3874	-1688	1471	-3335	-3335	-4150	-4240	-3935
Ednrb	1196	-3791	-3382	2790	2013	-3580	-1632	3997
F2r	1046	-1162	NA	-4052	569	-3026	-2307	NA
Lpar1	2234	-3056	-4086	1155	161	-4520	-393	967
Ntsr2	3069	NA	NA	NA	NA	NA	-126	NA
P2ry1	-3522	-4086	-2489	-4456	4387	1753	-2487	1221
P2ry2	3345	-3028	2864	-2559	4328	-3794	-4406	-3621
Penk	-1258	-4326	332	2153	1655	NA	4037	-1800
S1pr1	3839	-1993	-3998	-2544	-3978	-4646	-2239	4030
S1pr3	-4626	NA	-2585	NA	-4338	NA	NA	NA

---

---

REACTOME_INFLUENZA_LIFE_CYCLE

REACTOME_INFLUENZA_LIFE_CYCLE

metric	value
setSize	115
pMANOVA	1.69e-26
p.adjustMANOVA	7.24e-25
s.dist	0.667
s.de1	-0.305
s.de2	0.191
s.de3	-0.0431
s.de4	-0.154
s.de5	-0.284
s.de6	0.171
s.de7	0.419
s.de8	-0.0602
p.de1	7.7e-10
p.de2	0.000512
p.de3	0.313
p.de4	0.0052
p.de5	9.8e-09
p.de6	0.00181
p.de7	1.62e-15
p.de8	0.28

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 3 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 3 rows containing non-finite values (stat_density2d).
Removed 3 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 4 rows containing missing values

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 3 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 3 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 3 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 4 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 3 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 3 rows containing missing values (geom_point).
Removed 3 rows containing missing values (geom_point).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 4 rows containing missing values

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 2 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 3 rows containing missing values (geom_point).

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 3 rows containing missing values (geom_point).

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 3 rows containing missing values (geom_point).

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 4 rows containing missing values (geom_point).

Warning: Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning: Removed 8 rows containing non-finite values (stat_ydensity).

Warning: Removed 8 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d7	d1
Rpl12	4489	-4664
Rps4x	4507	-4476
Rps3	4369	-4613
Rplp0	4627	-4122
Rpl8	4596	-4099
Rps3a1	4603	-4063
Rpl3	3954	-4706
Rps9	4416	-4204
Rpl6	4546	-3907
Polr2a	4331	-4055
Rps6	3845	-4508
Rps23	4324	-3948
Rps24	4214	-3987
Rpl38	4164	-4020
Rps16	4200	-3928
Rps7	3680	-4463
Rpl14	4686	-3484
Rpsa	4336	-3686
Rpl18a	3690	-4328
Rps25	4421	-3603

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Aaas	1971.0	NA	3674.0	NA	-1588.0	-1184.0	2094.0	-2919.0
Calr	-4121.0	1891.0	1229.0	527.0	-4181.0	2440.0	2221.0	1640.0
Canx	-3644.0	-2410.0	3393.0	-3033.0	2244.0	4046.0	1652.0	-1462.0
Clta	-1110.0	3072.0	-3366.0	3543.0	-1902.0	3218.0	3090.0	1854.0
Cltc	-338.0	1695.0	1349.0	1123.0	2787.0	3708.0	3533.0	4555.0
Dnajc3	849.0	156.0	640.0	2501.0	-4252.0	2776.0	-248.0	-1758.0
Grsf1	4158.0	-4249.0	-661.0	-4249.0	4441.0	-2385.0	-118.0	2619.0
Gtf2f1	447.0	1152.0	-945.0	68.0	1997.0	2049.0	4406.0	-1180.0
Gtf2f2	-2196.0	2244.0	-1280.0	-3819.0	1807.0	2710.0	3202.0	253.0
Hsp90aa1	2636.0	-4071.0	-2875.0	-3904.0	-3251.0	-3962.0	-3899.0	4233.0
Hspa1b	4112.0	-3818.0	-3551.0	-1588.0	-4172.0	-4466.0	-4052.0	4315.0
Ipo5	1817.0	-2131.0	3317.0	-2839.0	4241.0	3995.0	1607.0	2111.0
Kpna1	1599.0	2894.0	2759.0	2279.0	2218.0	4445.0	1194.0	394.0
Kpnb1	-1728.0	2964.0	3347.0	1330.0	-4376.0	1423.0	1616.0	-459.0
Nup107	-2573.0	1815.0	2851.0	NA	22.0	3764.0	1604.0	-2478.0
Nup133	-2945.0	441.0	2990.0	-2573.0	1084.0	504.0	391.0	3329.0
Nup153	-478.0	-2958.0	-1014.0	-1737.0	-1450.0	-969.0	2713.0	2180.0
Nup155	-2200.0	-241.0	-911.0	-3928.0	362.0	-856.0	3405.0	-1445.0
Nup188	-266.0	2455.0	-3596.0	3727.0	-2538.0	2013.0	493.0	2117.0
Nup205	-1623.0	1387.0	939.0	3752.0	655.0	866.0	1399.0	-1110.0
Nup210	79.0	182.0	-1211.0	-2980.0	2050.0	4563.0	-2489.0	2423.0
Nup214	888.0	-373.0	-866.0	2618.0	-2233.0	-385.0	-1361.0	837.0
Nup35	1111.0	-287.0	3085.0	2731.0	-812.0	-3134.0	-704.0	2332.0
Nup37	2694.0	1375.0	-3411.0	-269.0	3783.0	-3200.0	-3113.0	-73.0
Nup43	-2023.0	3720.0	NA	1326.0	-3052.0	NA	329.0	NA
Nup54	-2727.0	-3183.0	-1077.0	-1773.0	987.0	-2932.0	-4231.0	1641.0
Nup62	2855.0	3349.0	282.0	-701.0	2480.0	1835.0	-1469.0	602.0
Nup85	-1789.0	4367.0	903.0	2778.0	-4284.0	1940.0	2129.0	1668.0
Nup88	-1059.0	937.0	-110.0	1743.0	2051.0	438.0	1992.0	555.0
Nup93	-820.0	4409.0	-3177.0	4175.0	-4770.0	1899.0	-85.0	1073.0
Nupl2	3363.0	589.0	-3482.0	4492.0	1585.0	3137.0	-2944.0	4298.0
Polr2a	-4055.0	2581.0	2570.0	4317.0	-3143.0	-92.0	4331.0	-871.0
Polr2b	-2820.0	-708.0	1693.0	1764.0	-31.0	2089.0	-357.0	2504.0
Polr2c	-851.0	-1229.0	-1174.0	553.0	-1509.0	-34.0	2961.0	612.0
Polr2d	2488.0	2119.0	-2898.0	-4103.0	-497.0	1979.0	-617.0	-1596.0
Polr2e	-2755.0	-284.0	1607.0	-2788.0	-1869.0	1138.0	-50.0	173.0
Polr2f	-2963.0	-1959.0	-867.0	-133.0	1065.0	3045.0	-3831.0	-3942.0
Polr2g	-3267.0	1690.0	-1176.0	-1833.0	-1839.0	3963.0	459.0	1635.0
Polr2h	-3277.0	-2058.0	4551.0	-2589.0	-2026.0	2438.0	1704.0	-2054.0
Polr2i	2986.0	-2456.0	2813.0	-3597.0	410.0	-3008.0	734.0	1805.0
Polr2j	-2499.0	-1032.0	1648.0	-1681.0	-1881.0	-1805.0	-1013.0	-93.0
Polr2k	3181.0	-1180.0	-354.0	-2773.0	-280.0	1701.0	-3104.0	-3269.0
Polr2l	1527.0	4132.0	2776.0	1207.0	-448.0	908.0	956.0	-4423.0
Pom121	3705.0	85.0	-1057.0	4563.0	-1487.0	-3694.0	-1932.0	2469.0
Rae1	-3229.0	3604.0	-905.0	2135.0	1557.0	1016.0	-662.0	-1385.0
Ran	-1425.0	2014.0	1262.0	1781.0	-3295.0	1516.0	4012.0	-2530.0
Ranbp2	2970.0	764.0	-687.0	1590.0	444.0	3911.0	1422.0	3569.0
Rpl10a	-1894.0	3571.0	-3834.0	2405.0	1149.0	1503.0	4350.0	846.0
Rpl11	-4496.0	1016.0	-4540.0	-2626.0	-2907.0	1099.0	752.0	-1922.0
Rpl12	-4664.0	281.0	-448.0	-793.0	-3814.0	4564.0	4489.0	-3529.0
Rpl13	-2756.0	1005.0	1051.0	841.0	611.0	3549.0	4241.0	-1591.0
Rpl14	-3484.0	2450.0	747.0	2965.0	-4204.0	-2832.0	4686.0	850.0
Rpl15	-2333.0	682.0	-2391.0	-1716.0	-434.0	145.0	4528.0	-2820.0
Rpl18	-2246.0	673.0	-464.0	-3786.0	-3107.0	828.0	3782.0	516.0
Rpl18a	-4328.0	2967.0	-1120.0	-1960.0	-1241.0	4412.0	3690.0	-90.0
Rpl19	-1606.0	1822.0	1611.0	-3606.0	-3471.0	-443.0	4499.0	-1853.0
Rpl22	-2109.0	-1577.0	-3978.0	3499.0	-1985.0	1261.0	3149.0	3311.0
Rpl23	-3347.0	-63.0	-2300.0	-4230.0	-2408.0	2686.0	3439.0	-793.0
Rpl23a	-1819.0	-1151.0	-2451.0	-3004.0	-1501.0	-226.0	3929.0	-128.0
Rpl24	2028.0	-1516.0	3293.0	-4019.0	-179.0	-1427.0	4426.0	-3218.0
Rpl26	-3053.0	1295.0	-4458.0	-997.0	-990.0	2647.0	3976.0	1105.0
Rpl27-ps3	1035.5	-4491.5	-977.5	-4204.5	392.5	-3423.5	595.5	97.5
Rpl27a	-765.0	3469.0	-283.0	-562.0	-4092.0	-2771.0	3658.0	-311.0
Rpl28	-3471.0	384.0	-3058.0	-731.0	-2274.0	934.0	3355.0	1698.0
Rpl29	-1550.0	1580.0	3636.0	-1529.0	168.0	618.0	1645.0	-3018.0
Rpl3	-4706.0	641.0	-4117.0	1354.0	-4672.0	-2254.0	3954.0	-3698.0
Rpl30	-4102.0	753.0	-4245.0	2797.0	-2289.0	1925.0	2942.0	2148.0
Rpl32	-2111.0	-114.0	-2493.0	-3242.0	-3875.0	-2355.0	4150.0	758.0
Rpl34	-1902.0	264.0	-2162.0	-2311.0	-3651.0	30.0	809.0	-346.0
Rpl35	-260.0	944.0	1544.0	-3339.0	501.0	1258.0	3955.0	1094.0
Rpl36al	-390.0	-968.0	2202.0	-3883.0	2525.0	3903.0	4182.0	-2045.0
Rpl37	-885.0	-3821.0	2983.0	-4392.0	-150.0	-1608.0	3687.0	-3038.0
Rpl37a	-4109.0	4049.0	548.0	-2516.0	-3379.0	3349.0	1579.0	-738.0
Rpl38	-4020.0	685.0	1227.0	-4372.0	-2807.0	2646.0	4164.0	-2260.0
Rpl39	2029.0	-908.0	-3610.0	-2995.0	-3301.0	-2757.0	633.0	89.0
Rpl3l	4079.0	-1994.0	1273.0	-3652.0	2840.0	-2171.0	-1577.0	500.0
Rpl4	-2436.0	1640.0	704.0	2374.0	-3375.0	2858.0	4681.0	2121.0
Rpl41	-569.0	688.0	-4588.0	-2653.0	-3790.0	-3147.0	3336.0	116.0
Rpl5	-4205.0	3942.0	-4600.0	3080.0	-3141.0	4170.0	2526.0	-272.0
Rpl6	-3907.0	935.0	2495.0	1234.0	-2151.0	2533.0	4546.0	580.0
Rpl8	-4099.0	1539.0	2520.0	676.0	-3408.0	-747.0	4596.0	-1407.0
Rplp0	-4122.0	1684.0	26.0	-47.0	-4420.0	2302.0	4627.0	-2369.0
Rplp1	-401.0	3710.0	-2113.0	-1112.0	-2215.0	1847.0	788.0	-1516.0
Rplp2	-3535.0	2764.0	3261.0	-2224.0	-1456.0	-823.0	2455.0	-2310.0
Rps11	-3099.0	37.0	731.0	-51.0	-3394.0	1460.0	1692.0	-3745.0
Rps12-ps3	-1676.0	NA	-4602.0	-4371.0	666.0	326.0	403.0	NA
Rps13	-3742.0	3659.0	2589.0	2506.0	-2969.0	-1105.0	3084.0	2082.0
Rps14	-2751.0	4064.0	-4050.0	1471.0	-4099.0	1787.0	3924.0	-2801.0
Rps15a	-3365.0	2480.0	-1674.0	-2749.0	-4205.0	-2025.0	3160.0	-125.0
Rps16	-3928.0	417.0	2289.0	1486.0	-4331.0	3460.0	4200.0	-299.0
Rps17	744.0	3046.0	-3851.0	-4065.0	-1359.0	3408.0	2365.0	316.0
Rps18	-4428.0	-2157.0	-657.0	-3732.0	-4029.0	381.0	3582.0	-887.0
Rps19	-1015.0	2899.0	-3396.0	-1095.0	-3824.0	516.0	4356.0	-188.0
Rps20	-3879.0	3874.0	3106.0	367.0	-4671.0	2731.0	3931.0	-2656.0
Rps21	-163.0	1078.0	-567.0	-4304.0	-2536.0	-4229.0	4069.0	-3318.0
Rps23	-3948.0	817.0	-3714.0	-2050.0	-3125.0	1478.0	4324.0	-1081.0
Rps24	-3987.0	195.0	-1883.0	179.0	-3255.0	1024.0	4214.0	-3146.0
Rps25	-3603.0	1296.0	4490.0	-2646.0	-3102.0	134.0	4421.0	-1871.0
Rps26	-3489.0	3699.0	1791.0	-3069.0	-4324.0	3340.0	3518.0	-2951.0
Rps27	-456.0	2984.0	-3857.0	-4315.0	-3723.0	-3843.0	4104.0	-3349.0
Rps27a	-418.0	3577.0	-2139.0	4048.0	-3761.0	-1240.0	2510.0	641.0
Rps29	4695.0	1750.0	4128.0	-4506.0	217.0	-4132.0	2325.0	-2576.0
Rps3	-4613.0	558.0	-1151.0	-1016.0	-4248.0	3067.0	4369.0	1031.0
Rps3a1	-4063.0	1143.0	2961.0	-1734.0	-2087.0	4071.0	4603.0	-889.0
Rps4x	-4476.0	3694.0	2637.0	-2229.0	-3092.0	3557.0	4507.0	-2256.0
Rps5	-2186.0	982.0	-4240.0	-1041.0	-2273.0	2525.0	4238.0	2409.0
Rps6	-4508.0	-1590.0	-3432.0	-837.0	-3496.0	730.0	3845.0	-1317.0
Rps7	-4463.0	-2011.0	-2440.0	910.0	-3663.0	2639.0	3680.0	-2178.0
Rps8	-4062.0	2318.0	3589.0	1616.0	-3146.0	3166.0	2935.0	-3655.0
Rps9	-4204.0	1585.0	3994.0	1252.0	-4213.0	-917.0	4416.0	-2708.0
Rpsa	-3686.0	3186.0	152.0	-1880.0	-2226.0	2889.0	4336.0	270.0
Seh1l	4206.0	2854.0	4092.0	2281.0	1776.0	-1707.0	3346.0	-4110.0
Tpr	2631.0	-101.0	-1511.0	-590.0	4111.0	2629.0	1941.0	2242.0
Uba52	4621.0	4487.0	1045.0	-3153.0	-367.0	-283.0	1322.0	733.0
Xpo1	-527.0	-17.0	2672.0	3192.0	-878.0	-2772.0	-2538.0	486.0

---

---

REACTOME_SIGNALING_BY_NOTCH3

REACTOME_SIGNALING_BY_NOTCH3

metric	value
setSize	12
pMANOVA	0.304
p.adjustMANOVA	0.482
s.dist	0.663
s.de1	-0.217
s.de2	-0.199
s.de3	-0.153
s.de4	-0.269
s.de5	-0.261
s.de6	-0.381
s.de7	-0.0881
s.de8	-0.191
p.de1	0.293
p.de2	0.272
p.de3	0.52
p.de4	0.262
p.de5	0.196
p.de6	0.0841
p.de7	0.444
p.de8	0.16

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 3 rows containing non-finite values (stat_density2d).

Warning: Removed 3 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 3 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 3 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 3 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 3 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 3 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 3 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).
Removed 2 rows containing non-finite values (stat_density2d).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 3 rows containing missing values (geom_point).

Warning: Removed 3 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 3 rows containing missing values

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 3 rows containing missing values (geom_point).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 3 rows containing missing values (geom_point).

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 3 rows containing missing values (geom_point).

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 3 rows containing missing values (geom_point).

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 3 rows containing missing values (geom_point).

Warning: Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removed 2 rows containing missing values

Warning: Removed 2 rows containing missing values (geom_point).

Warning: Removed 3 rows containing missing values (geom_point).

Warning: Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).
Removed 2 rows containing missing values (geom_point).

Warning: Removed 2 rows containing non-finite values (stat_bin).

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning: Removed 11 rows containing non-finite values (stat_ydensity).

Warning: Removed 11 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d6	d4
Aph1b	-3689	-2753
Dll4	-3176	-2351
Adam10	-3990	-1571
Jag1	-2532	-1789
Psenen	-1241	-3137
Ncstn	-3198	-657
Aph1a	-299	-3244

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
Adam10	3	-1345	-2589	-1571	-2846	-3990	-1459	-4148
Aph1a	1584	-3145	-1248	-3244	1164	-299	-3572	1807
Aph1b	-1372	NA	NA	-2753	1575	-3689	NA	NA
Dll1	-1806	NA	NA	NA	-4131	NA	NA	NA
Dll4	-1636	NA	-2495	-2351	-3361	-3176	1991	1634
Jag1	-838	-1868	-530	-1789	-2270	-2532	-289	-3160
Jag2	-2923	-2045	664	1407	-4315	-3554	-4457	-3806
Ncstn	333	82	-3989	-657	-1210	-3198	2897	3099
Notch3	-3505	-3410	-1097	-1714	1426	448	-4556	-2100
Psen1	-599	-1210	398	-1311	827	386	3397	1802
Psen2	-3748	879	3885	3486	-2205	181	1786	-4239
Psenen	2961	3315	-381	-3137	-1735	-1241	686	-341

---

---

REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC

REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC

metric	value
setSize	15
pMANOVA	0.0415
p.adjustMANOVA	0.135
s.dist	0.663
s.de1	-0.425
s.de2	-0.0606
s.de3	0.0983
s.de4	-0.0773
s.de5	0.0117
s.de6	0.416
s.de7	0.257
s.de8	-0.00914
p.de1	0.00508
p.de2	0.67
p.de3	0.526
p.de4	0.616
p.de5	0.916
p.de6	0.00533
p.de7	0.0875
p.de8	0.923

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).
Removed 1 rows containing non-finite values (stat_density2d).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning in ggally_statistic(data = data, mapping = mapping, na.rm = na.rm, :
Removing 1 row that contained a missing value

Warning: Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).
Removed 1 rows containing missing values (geom_point).

Warning: Removed 1 rows containing non-finite values (stat_bin).

Warning: Removed 2867 rows containing non-finite values (stat_ydensity).

Warning: Removed 2867 rows containing non-finite values (stat_boxplot).

Warning: Removed 6 rows containing non-finite values (stat_ydensity).

Warning: Removed 6 rows containing non-finite values (stat_boxplot).

Warning in xtfrm.data.frame(x): cannot xtfrm data frames

Top 20 genes

Gene	d1	d6
B2m	-4584	4135
Hspa5	-3861	4217
Tap2	-4543	3555
Canx	-3644	4046
Erap1	-3142	3854
Calr	-4121	2440
Sec24d	-3826	631
Sec31a	-226	4438

Click HERE to show all gene set members

All member genes

	de1	de2	de3	de4	de5	de6	de7	de8
B2m	-4584	44	-3363	-968	544	4135	2648	-3301
Calr	-4121	1891	1229	527	-4181	2440	2221	1640
Canx	-3644	-2410	3393	-3033	2244	4046	1652	-1462
Erap1	-3142	3252	4521	-3430	2204	3854	-1182	368
Hspa5	-3861	-519	-1527	-2353	-243	4217	1090	3802
Pdia3	-3201	-3982	-4469	-1150	-1382	-3861	-1358	1848
Sar1b	1600	3179	923	1918	-475	4203	1453	-3082
Sec13	-413	134	1830	-19	2253	-862	1857	-2672
Sec23a	4551	-2035	3894	1370	3859	3383	2744	3910
Sec24b	-563	-1165	3583	1538	-4018	-1781	4249	1508
Sec24c	101	578	-233	3461	1372	-532	-2524	1378
Sec24d	-3826	-3868	993	-887	-1560	631	-1137	-2868
Sec31a	-226	2273	-1577	-3245	1853	4438	2925	1622
Tap1	-3691	NA	NA	NA	-1724	NA	NA	NA
Tap2	-4543	-1557	-2441	1968	-2261	3555	3833	-3550

---

---

Here is the session info with all the versions of packages used.

sessionInfo()

## R version 4.2.1 (2022-06-23)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.1 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## attached base packages:
## [1] stats4    stats     graphics  grDevices utils     datasets  methods  
## [8] base     
## 
## other attached packages:
##  [1] plyr_1.8.7                  pkgload_1.3.0              
##  [3] GGally_2.1.2                gtools_3.9.2.2             
##  [5] echarts4r_0.4.4             beeswarm_0.4.0             
##  [7] vioplot_0.3.7               sm_2.2-5.7                 
##  [9] kableExtra_1.3.4            topconfects_1.12.0         
## [11] limma_3.52.1                eulerr_6.1.1               
## [13] mitch_1.8.0                 MASS_7.3-58                
## [15] fgsea_1.22.0                gplots_3.1.3               
## [17] DESeq2_1.36.0               SummarizedExperiment_1.26.1
## [19] Biobase_2.56.0              MatrixGenerics_1.8.0       
## [21] matrixStats_0.62.0          GenomicRanges_1.48.0       
## [23] GenomeInfoDb_1.32.2         IRanges_2.30.0             
## [25] S4Vectors_0.34.0            BiocGenerics_0.42.0        
## [27] reshape2_1.4.4              forcats_0.5.1              
## [29] stringr_1.4.0               dplyr_1.0.9                
## [31] purrr_0.3.4                 readr_2.1.2                
## [33] tidyr_1.2.0                 tibble_3.1.7               
## [35] ggplot2_3.3.6               tidyverse_1.3.1            
## [37] zoo_1.8-10                 
## 
## loaded via a namespace (and not attached):
##   [1] readxl_1.4.0           backports_1.4.1        fastmatch_1.1-3       
##   [4] systemfonts_1.0.4      splines_4.2.1          BiocParallel_1.30.3   
##   [7] digest_0.6.29          htmltools_0.5.2        fansi_1.0.3           
##  [10] magrittr_2.0.3         memoise_2.0.1          tzdb_0.3.0            
##  [13] Biostrings_2.64.0      annotate_1.74.0        modelr_0.1.8          
##  [16] svglite_2.1.0          prettyunits_1.1.1      colorspace_2.0-3      
##  [19] blob_1.2.3             rvest_1.0.2            haven_2.5.0           
##  [22] xfun_0.31              crayon_1.5.1           RCurl_1.98-1.7        
##  [25] jsonlite_1.8.0         genefilter_1.78.0      survival_3.4-0        
##  [28] glue_1.6.2             gtable_0.3.0           zlibbioc_1.42.0       
##  [31] XVector_0.36.0         webshot_0.5.3          DelayedArray_0.22.0   
##  [34] scales_1.2.0           DBI_1.1.3              Rcpp_1.0.8.3          
##  [37] viridisLite_0.4.0      xtable_1.8-4           progress_1.2.2        
##  [40] bit_4.0.4              htmlwidgets_1.5.4      httr_1.4.3            
##  [43] RColorBrewer_1.1-3     ellipsis_0.3.2         pkgconfig_2.0.3       
##  [46] reshape_0.8.9          XML_3.99-0.10          farver_2.1.0          
##  [49] sass_0.4.1             dbplyr_2.2.1           locfit_1.5-9.5        
##  [52] utf8_1.2.2             tidyselect_1.1.2       labeling_0.4.2        
##  [55] rlang_1.0.3            later_1.3.0            AnnotationDbi_1.58.0  
##  [58] munsell_0.5.0          cellranger_1.1.0       tools_4.2.1           
##  [61] cachem_1.0.6           cli_3.3.0              generics_0.1.2        
##  [64] RSQLite_2.2.14         broom_0.8.0            evaluate_0.15         
##  [67] fastmap_1.1.0          yaml_2.3.5             knitr_1.39            
##  [70] bit64_4.0.5            fs_1.5.2               caTools_1.18.2        
##  [73] KEGGREST_1.36.2        mime_0.12              xml2_1.3.3            
##  [76] compiler_4.2.1         rstudioapi_0.13        png_0.1-7             
##  [79] reprex_2.0.1           geneplotter_1.74.0     bslib_0.3.1           
##  [82] stringi_1.7.6          highr_0.9              lattice_0.20-45       
##  [85] Matrix_1.4-1           vctrs_0.4.1            pillar_1.7.0          
##  [88] lifecycle_1.0.1        jquerylib_0.1.4        data.table_1.14.2     
##  [91] bitops_1.0-7           httpuv_1.6.5           R6_2.5.1              
##  [94] promises_1.2.0.1       KernSmooth_2.23-20     gridExtra_2.3         
##  [97] codetools_0.2-18       assertthat_0.2.1       withr_2.5.0           
## [100] GenomeInfoDbData_1.2.8 parallel_4.2.1         hms_1.1.1             
## [103] grid_4.2.1             rmarkdown_2.14         shiny_1.7.1           
## [106] lubridate_1.8.0

END of report