Mitch Report

date generated: 2022-05-11

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

##                    x
## 5_8S_rRNA  0.5111728
## 7SK        1.7262111
## A1BG       0.8134692
## A1BG-AS1   0.4301003
## A2M        0.9269446
## A2M-AS1   -0.6001928

Here are some metrics about the input data profile:

Profile metrics

	Profile metrics
num_genesets	2512
num_genes_in_profile	20208
duplicated_genes_present	0
num_profile_genes_in_sets	8971
num_profile_genes_not_in_sets	11237

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used: GMT file of genesets: ReactomePathways.gmt

Gene sets metrics

	Gene sets metrics
num_genesets	2512
num_genesets_excluded	1061
num_genesets_included	1451

Differential pathway expression

Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

set	setSize	pANOVA	s.dist	p.adjustANOVA
Classical antibody-mediated complement activation	73	4.12e-34	-0.8230	5.97e-31
FCGR activation	80	2.18e-33	-0.7770	1.58e-30
Scavenging of heme from plasma	74	7.04e-33	-0.8020	3.41e-30
Creation of C4 and C2 activators	78	1.85e-32	-0.7760	6.69e-30
Initial triggering of complement	85	2.36e-32	-0.7420	6.86e-30
Role of LAT2/NTAL/LAB on calcium mobilization	78	1.71e-28	-0.7240	4.14e-26
CD22 mediated BCR regulation	61	9.90e-27	-0.7910	2.05e-24
Role of phospholipids in phagocytosis	93	1.46e-26	-0.6390	2.64e-24
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	178	6.43e-25	-0.4480	1.04e-22
FCERI mediated MAPK activation	94	8.62e-24	-0.6000	1.25e-21
Regulation of Complement cascade	102	2.42e-23	-0.5700	3.19e-21
Complement cascade	109	2.76e-23	-0.5510	3.33e-21
FCERI mediated Ca+2 mobilization	93	1.20e-22	-0.5870	1.34e-20
Binding and Uptake of Ligands by Scavenger Receptors	102	2.12e-22	-0.5570	2.19e-20
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	86	5.66e-21	-0.5860	4.81e-19
FCGR3A-mediated phagocytosis	127	5.96e-21	-0.4820	4.81e-19
Leishmania phagocytosis	127	5.96e-21	-0.4820	4.81e-19
Parasite infection	127	5.96e-21	-0.4820	4.81e-19
Regulation of actin dynamics for phagocytic cup formation	129	2.44e-20	-0.4710	1.82e-18
FCGR3A-mediated IL10 synthesis	104	2.51e-20	-0.5240	1.82e-18
Eukaryotic Translation Elongation	93	5.43e-17	0.5020	3.75e-15
Nervous system development	513	1.62e-16	0.2130	1.07e-14
FCERI mediated NF-kB activation	141	1.88e-16	-0.4010	1.19e-14
Fcgamma receptor (FCGR) dependent phagocytosis	154	6.30e-16	-0.3770	3.81e-14
Axon guidance	492	1.04e-15	0.2110	6.02e-14
Peptide chain elongation	88	1.43e-15	0.4920	7.98e-14
Formation of a pool of free 40S subunits	100	3.00e-15	0.4560	1.61e-13
Metabolism of proteins	1711	4.23e-15	0.1140	2.19e-13
Viral mRNA Translation	88	4.88e-15	0.4830	2.44e-13
GTP hydrolysis and joining of the 60S ribosomal subunit	111	6.02e-15	0.4290	2.91e-13
L13a-mediated translational silencing of Ceruloplasmin expression	110	8.28e-15	0.4280	3.76e-13
Response of EIF2AK4 (GCN2) to amino acid deficiency	100	8.29e-15	0.4490	3.76e-13
SRP-dependent cotranslational protein targeting to membrane	111	1.00e-14	0.4250	4.40e-13
Selenocysteine synthesis	92	1.14e-14	0.4660	4.89e-13
Eukaryotic Translation Termination	92	1.68e-14	0.4630	6.98e-13
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	94	3.14e-14	0.4530	1.26e-12
Cell surface interactions at the vascular wall	187	3.48e-14	-0.3210	1.36e-12
Cap-dependent Translation Initiation	118	2.16e-13	0.3910	8.05e-12
Eukaryotic Translation Initiation	118	2.16e-13	0.3910	8.05e-12
Selenoamino acid metabolism	115	3.08e-13	0.3930	1.12e-11
Cellular response to starvation	151	1.17e-12	0.3350	4.13e-11
Extracellular matrix organization	264	2.04e-12	0.2510	7.04e-11
Cell Cycle	624	2.70e-12	-0.1640	9.01e-11
Developmental Biology	797	2.73e-12	0.1460	9.01e-11
Signal Transduction	2166	5.92e-12	0.0903	1.91e-10
tRNA processing in the mitochondrion	26	6.30e-12	0.7780	1.99e-10
Cell Cycle, Mitotic	503	9.78e-12	-0.1770	3.02e-10
Translation	294	1.79e-11	0.2280	5.42e-10
Anti-inflammatory response favouring Leishmania parasite infection	179	2.16e-11	-0.2900	6.26e-10
Leishmania parasite growth and survival	179	2.16e-11	-0.2900	6.26e-10

---

Results (complete table)

Click HERE to show results for all gene sets

Complete results

set	setSize	pANOVA	s.dist	p.adjustANOVA
Classical antibody-mediated complement activation	73	4.12e-34	-0.823000	5.97e-31
FCGR activation	80	2.18e-33	-0.777000	1.58e-30
Scavenging of heme from plasma	74	7.04e-33	-0.802000	3.41e-30
Creation of C4 and C2 activators	78	1.85e-32	-0.776000	6.69e-30
Initial triggering of complement	85	2.36e-32	-0.742000	6.86e-30
Role of LAT2/NTAL/LAB on calcium mobilization	78	1.71e-28	-0.724000	4.14e-26
CD22 mediated BCR regulation	61	9.90e-27	-0.791000	2.05e-24
Role of phospholipids in phagocytosis	93	1.46e-26	-0.639000	2.64e-24
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	178	6.43e-25	-0.448000	1.04e-22
FCERI mediated MAPK activation	94	8.62e-24	-0.600000	1.25e-21
Regulation of Complement cascade	102	2.42e-23	-0.570000	3.19e-21
Complement cascade	109	2.76e-23	-0.551000	3.33e-21
FCERI mediated Ca+2 mobilization	93	1.20e-22	-0.587000	1.34e-20
Binding and Uptake of Ligands by Scavenger Receptors	102	2.12e-22	-0.557000	2.19e-20
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	86	5.66e-21	-0.586000	4.81e-19
FCGR3A-mediated phagocytosis	127	5.96e-21	-0.482000	4.81e-19
Leishmania phagocytosis	127	5.96e-21	-0.482000	4.81e-19
Parasite infection	127	5.96e-21	-0.482000	4.81e-19
Regulation of actin dynamics for phagocytic cup formation	129	2.44e-20	-0.471000	1.82e-18
FCGR3A-mediated IL10 synthesis	104	2.51e-20	-0.524000	1.82e-18
Eukaryotic Translation Elongation	93	5.43e-17	0.502000	3.75e-15
Nervous system development	513	1.62e-16	0.213000	1.07e-14
FCERI mediated NF-kB activation	141	1.88e-16	-0.401000	1.19e-14
Fcgamma receptor (FCGR) dependent phagocytosis	154	6.30e-16	-0.377000	3.81e-14
Axon guidance	492	1.04e-15	0.211000	6.02e-14
Peptide chain elongation	88	1.43e-15	0.492000	7.98e-14
Formation of a pool of free 40S subunits	100	3.00e-15	0.456000	1.61e-13
Metabolism of proteins	1711	4.23e-15	0.114000	2.19e-13
Viral mRNA Translation	88	4.88e-15	0.483000	2.44e-13
GTP hydrolysis and joining of the 60S ribosomal subunit	111	6.02e-15	0.429000	2.91e-13
L13a-mediated translational silencing of Ceruloplasmin expression	110	8.28e-15	0.428000	3.76e-13
Response of EIF2AK4 (GCN2) to amino acid deficiency	100	8.29e-15	0.449000	3.76e-13
SRP-dependent cotranslational protein targeting to membrane	111	1.00e-14	0.425000	4.40e-13
Selenocysteine synthesis	92	1.14e-14	0.466000	4.89e-13
Eukaryotic Translation Termination	92	1.68e-14	0.463000	6.98e-13
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	94	3.14e-14	0.453000	1.26e-12
Cell surface interactions at the vascular wall	187	3.48e-14	-0.321000	1.36e-12
Cap-dependent Translation Initiation	118	2.16e-13	0.391000	8.05e-12
Eukaryotic Translation Initiation	118	2.16e-13	0.391000	8.05e-12
Selenoamino acid metabolism	115	3.08e-13	0.393000	1.12e-11
Cellular response to starvation	151	1.17e-12	0.335000	4.13e-11
Extracellular matrix organization	264	2.04e-12	0.251000	7.04e-11
Cell Cycle	624	2.70e-12	-0.164000	9.01e-11
Developmental Biology	797	2.73e-12	0.146000	9.01e-11
Signal Transduction	2166	5.92e-12	0.090300	1.91e-10
tRNA processing in the mitochondrion	26	6.30e-12	0.778000	1.99e-10
Cell Cycle, Mitotic	503	9.78e-12	-0.177000	3.02e-10
Translation	294	1.79e-11	0.228000	5.42e-10
Anti-inflammatory response favouring Leishmania parasite infection	179	2.16e-11	-0.290000	6.26e-10
Leishmania parasite growth and survival	179	2.16e-11	-0.290000	6.26e-10
Signaling by ROBO receptors	207	7.06e-11	0.263000	2.01e-09
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	114	1.15e-10	0.349000	3.15e-09
Nonsense-Mediated Decay (NMD)	114	1.15e-10	0.349000	3.15e-09
Signaling by Receptor Tyrosine Kinases	471	2.26e-10	0.171000	6.09e-09
rRNA processing	214	4.92e-10	0.247000	1.30e-08
Fc epsilon receptor (FCERI) signaling	194	8.12e-10	-0.256000	2.10e-08
Regulation of expression of SLITs and ROBOs	164	1.58e-09	0.273000	4.03e-08
Collagen formation	84	1.83e-09	0.379000	4.56e-08
Diseases of glycosylation	128	1.85e-09	0.308000	4.56e-08
Signaling by the B Cell Receptor (BCR)	164	1.51e-08	-0.256000	3.66e-07
Influenza Viral RNA Transcription and Replication	135	1.93e-08	0.280000	4.59e-07
Influenza Infection	154	2.23e-08	0.261000	5.22e-07
Diseases associated with glycosaminoglycan metabolism	37	2.73e-08	0.528000	6.29e-07
Innate Immune System	992	4.82e-08	-0.103000	1.09e-06
Leishmania infection	260	5.10e-08	-0.196000	1.14e-06
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)	96	9.75e-08	0.315000	2.14e-06
Post-translational protein phosphorylation	83	1.33e-07	0.335000	2.89e-06
Post-translational protein modification	1244	1.50e-07	0.088700	3.21e-06
Collagen biosynthesis and modifying enzymes	63	1.94e-07	0.379000	4.09e-06
Diseases of metabolism	207	2.00e-07	0.210000	4.15e-06
DNA strand elongation	32	2.38e-07	-0.528000	4.84e-06
Activation of ATR in response to replication stress	37	2.40e-07	-0.491000	4.84e-06
Major pathway of rRNA processing in the nucleolus and cytosol	180	3.41e-07	0.220000	6.78e-06
Activation of the pre-replicative complex	32	5.64e-07	-0.511000	1.11e-05
Glycosaminoglycan metabolism	110	6.86e-07	0.274000	1.33e-05
rRNA processing in the nucleus and cytosol	190	7.36e-07	0.208000	1.40e-05
DNA Repair	294	7.77e-07	-0.168000	1.46e-05
Formation of the ternary complex, and subsequently, the 43S complex	51	8.53e-07	0.398000	1.59e-05
Ribosomal scanning and start codon recognition	58	9.05e-07	0.373000	1.66e-05
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.	126	9.22e-07	0.253000	1.67e-05
DNA Double-Strand Break Repair	138	1.06e-06	-0.241000	1.89e-05
Class B/2 (Secretin family receptors)	69	1.12e-06	0.339000	1.98e-05
Cell Cycle Checkpoints	259	1.53e-06	-0.174000	2.67e-05
Translation initiation complex formation	58	1.94e-06	0.361000	3.35e-05
Cellular responses to stimuli	683	2.61e-06	0.106000	4.46e-05
rRNA processing in the mitochondrion	24	3.99e-06	0.544000	6.72e-05
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S	59	4.14e-06	0.347000	6.90e-05
ECM proteoglycans	50	4.36e-06	0.375000	7.19e-05
Respiratory electron transport	103	4.86e-06	0.261000	7.92e-05
Chondroitin sulfate/dermatan sulfate metabolism	46	5.06e-06	0.389000	8.16e-05
DNA Replication	143	5.29e-06	-0.221000	8.44e-05
Cytokine Signaling in Immune system	630	5.37e-06	0.106000	8.47e-05
G1/S-Specific Transcription	29	5.58e-06	-0.487000	8.70e-05
Transcriptional regulation by RUNX2	117	7.81e-06	0.239000	1.21e-04
Interferon alpha/beta signaling	57	9.48e-06	0.339000	1.45e-04
Cellular responses to stress	673	1.03e-05	0.099800	1.56e-04
Neutrophil degranulation	461	1.18e-05	-0.119000	1.74e-04
Assembly of collagen fibrils and other multimeric structures	53	1.18e-05	0.348000	1.74e-04
Homology Directed Repair	109	1.20e-05	-0.243000	1.76e-04
Syndecan interactions	19	1.23e-05	0.579000	1.79e-04
O-linked glycosylation	94	1.45e-05	0.259000	2.09e-04
Cell-cell junction organization	45	1.70e-05	0.370000	2.42e-04
ER to Golgi Anterograde Transport	132	1.84e-05	0.216000	2.60e-04
Non-integrin membrane-ECM interactions	40	1.91e-05	0.391000	2.67e-04
The citric acid (TCA) cycle and respiratory electron transport	173	2.00e-05	0.188000	2.76e-04
Signaling by NTRK1 (TRKA)	112	2.32e-05	0.231000	3.17e-04
Heme biosynthesis	13	2.88e-05	-0.670000	3.90e-04
Signaling by NTRKs	130	3.20e-05	0.211000	4.30e-04
M Phase	360	3.49e-05	-0.127000	4.65e-04
Cargo concentration in the ER	31	3.84e-05	0.427000	5.06e-04
Nuclear Events (kinase and transcription factor activation)	59	4.67e-05	0.306000	6.10e-04
Diseases of signal transduction by growth factor receptors and second messengers	406	4.88e-05	0.118000	6.26e-04
Metabolism of porphyrins	21	4.91e-05	-0.512000	6.26e-04
Synthesis of DNA	118	4.92e-05	-0.216000	6.26e-04
Metabolism of amino acids and derivatives	336	4.99e-05	0.129000	6.29e-04
RHO GTPase cycle	430	5.08e-05	0.114000	6.36e-04
Mitotic Prometaphase	185	5.51e-05	-0.172000	6.78e-04
Cell-Cell communication	102	5.51e-05	0.231000	6.78e-04
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)	103	5.56e-05	-0.230000	6.78e-04
S Phase	160	6.15e-05	-0.184000	7.39e-04
O-glycosylation of TSR domain-containing proteins	36	6.16e-05	0.386000	7.39e-04
G0 and Early G1	27	6.35e-05	-0.445000	7.55e-04
Cell junction organization	70	7.42e-05	0.274000	8.76e-04
NGF-stimulated transcription	37	7.61e-05	0.376000	8.90e-04
Defective B3GALTL causes PpS	35	7.81e-05	0.386000	9.06e-04
Extra-nuclear estrogen signaling	67	8.52e-05	0.278000	9.82e-04
Metabolism	1856	1.03e-04	0.054600	1.17e-03
Diseases associated with O-glycosylation of proteins	57	1.15e-04	0.295000	1.31e-03
Transport to the Golgi and subsequent modification	157	1.27e-04	0.177000	1.43e-03
Interleukin-10 signaling	38	1.33e-04	0.358000	1.49e-03
Adherens junctions interactions	25	1.44e-04	0.439000	1.60e-03
Mitotic G1 phase and G1/S transition	148	1.52e-04	-0.180000	1.67e-03
RUNX2 regulates osteoblast differentiation	23	1.57e-04	0.455000	1.72e-03
Chromosome Maintenance	105	1.71e-04	-0.212000	1.85e-03
G2/M Checkpoints	138	1.72e-04	-0.185000	1.85e-03
Regulation of insulin secretion	66	1.74e-04	0.267000	1.85e-03
HDR through Homologous Recombination (HRR)	66	1.81e-04	-0.267000	1.91e-03
Unwinding of DNA	12	1.82e-04	-0.624000	1.91e-03
COPII-mediated vesicle transport	66	2.01e-04	0.265000	2.10e-03
Intraflagellar transport	39	2.06e-04	0.343000	2.14e-03
Interferon Signaling	180	2.10e-04	0.160000	2.16e-03
Signaling by BMP	24	2.14e-04	0.437000	2.18e-03
Keratan sulfate degradation	11	2.15e-04	0.644000	2.18e-03
Striated Muscle Contraction	30	2.27e-04	0.389000	2.28e-03
Interleukin-6 family signaling	22	2.34e-04	0.453000	2.34e-03
RUNX2 regulates bone development	30	2.40e-04	0.387000	2.38e-03
Adaptive Immune System	762	2.42e-04	-0.078300	2.38e-03
Polo-like kinase mediated events	16	2.43e-04	-0.530000	2.38e-03
Chondroitin sulfate biosynthesis	16	2.44e-04	0.530000	2.38e-03
Complex I biogenesis	57	2.69e-04	0.279000	2.60e-03
Lagging Strand Synthesis	20	2.81e-04	-0.469000	2.70e-03
Muscle contraction	158	3.80e-04	0.164000	3.63e-03
Transport of Mature Transcript to Cytoplasm	81	3.85e-04	-0.228000	3.65e-03
G1/S Transition	130	4.50e-04	-0.178000	4.24e-03
Extension of Telomeres	51	5.28e-04	-0.281000	4.94e-03
Asparagine N-linked glycosylation	273	5.53e-04	0.122000	5.14e-03
Membrane Trafficking	579	5.71e-04	0.083900	5.28e-03
Signaling by FGFR	75	6.77e-04	0.227000	6.21e-03
CLEC7A (Dectin-1) induces NFAT activation	11	7.11e-04	0.589000	6.49e-03
MAPK family signaling cascades	290	7.42e-04	0.115000	6.73e-03
Homologous DNA Pairing and Strand Exchange	42	8.21e-04	-0.298000	7.40e-03
Netrin-1 signaling	44	9.29e-04	0.289000	8.32e-03
Signaling by TGFB family members	98	9.70e-04	0.193000	8.60e-03
CS/DS degradation	11	9.71e-04	0.574000	8.60e-03
Antimicrobial peptides	33	9.78e-04	-0.332000	8.60e-03
Resolution of Sister Chromatid Cohesion	105	1.03e-03	-0.185000	8.97e-03
Processive synthesis on the lagging strand	15	1.17e-03	-0.484000	1.02e-02
Collagen chain trimerization	40	1.19e-03	0.296000	1.02e-02
Ca2+ pathway	57	1.21e-03	0.248000	1.04e-02
Resolution of D-Loop Structures	33	1.29e-03	-0.324000	1.10e-02
DNA Replication Pre-Initiation	100	1.38e-03	-0.185000	1.17e-02
Beta-catenin independent WNT signaling	138	1.39e-03	0.158000	1.17e-02
VEGFR2 mediated cell proliferation	19	1.40e-03	0.423000	1.17e-02
Signaling by Hippo	20	1.45e-03	0.411000	1.21e-02
Interleukin-4 and Interleukin-13 signaling	101	1.51e-03	0.183000	1.25e-02
Neurotransmitter receptors and postsynaptic signal transmission	140	1.53e-03	0.155000	1.26e-02
Presynaptic phase of homologous DNA pairing and strand exchange	39	1.54e-03	-0.293000	1.26e-02
Telomere C-strand (Lagging Strand) Synthesis	34	1.62e-03	-0.312000	1.32e-02
Signaling by FGFR1	43	1.64e-03	0.277000	1.33e-02
Resolution of D-loop Structures through Holliday Junction Intermediates	32	1.70e-03	-0.320000	1.37e-02
Signaling by VEGF	103	1.74e-03	0.179000	1.40e-02
Zinc transporters	13	1.77e-03	0.501000	1.41e-02
Keratan sulfate/keratin metabolism	32	1.77e-03	0.319000	1.41e-02
Myogenesis	23	1.83e-03	0.375000	1.44e-02
RND1 GTPase cycle	39	1.85e-03	0.288000	1.45e-02
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal	92	1.87e-03	-0.188000	1.45e-02
Amplification of signal from the kinetochores	92	1.87e-03	-0.188000	1.45e-02
Transport of small molecules	588	1.91e-03	0.075000	1.47e-02
CDC6 association with the ORC:origin complex	11	1.97e-03	-0.539000	1.51e-02
Semaphorin interactions	63	1.98e-03	0.225000	1.52e-02
COPI-mediated anterograde transport	81	2.04e-03	0.198000	1.55e-02
Mitotic Spindle Checkpoint	109	2.06e-03	-0.171000	1.56e-02
Processing of Capped Intron-Containing Pre-mRNA	238	2.10e-03	-0.116000	1.58e-02
Processing of DNA double-strand break ends	70	2.23e-03	-0.211000	1.67e-02
Transport of Mature mRNA derived from an Intron-Containing Transcript	72	2.40e-03	-0.207000	1.78e-02
mRNA 3’-end processing	56	2.59e-03	-0.233000	1.92e-02
IL-6-type cytokine receptor ligand interactions	15	2.63e-03	0.449000	1.93e-02
Fanconi Anemia Pathway	36	2.73e-03	-0.289000	2.00e-02
Transport of Mature mRNAs Derived from Intronless Transcripts	43	2.86e-03	-0.263000	2.08e-02
Signaling by Hedgehog	132	2.98e-03	0.150000	2.16e-02
RND3 GTPase cycle	38	3.04e-03	0.278000	2.20e-02
Removal of the Flap Intermediate	14	3.12e-03	-0.456000	2.24e-02
DCC mediated attractive signaling	13	3.14e-03	0.473000	2.25e-02
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	33	3.27e-03	0.296000	2.33e-02
PCNA-Dependent Long Patch Base Excision Repair	21	3.38e-03	-0.369000	2.39e-02
Defective B3GALT6 causes EDSP2 and SEMDJL1	17	3.42e-03	0.410000	2.41e-02
Neuronal System	292	3.45e-03	0.099500	2.42e-02
Opioid Signalling	81	3.81e-03	0.186000	2.66e-02
NOTCH2 Activation and Transmission of Signal to the Nucleus	22	3.86e-03	0.356000	2.67e-02
Resolution of AP sites via the multiple-nucleotide patch replacement pathway	25	3.87e-03	-0.334000	2.67e-02
Cargo trafficking to the periciliary membrane	46	3.99e-03	0.245000	2.75e-02
Synthesis of Leukotrienes (LT) and Eoxins (EX)	16	4.02e-03	-0.415000	2.75e-02
Mitotic Metaphase and Anaphase	225	4.29e-03	-0.111000	2.92e-02
Ras activation upon Ca2+ influx through NMDA receptor	17	4.36e-03	0.399000	2.95e-02
Integration of energy metabolism	96	4.38e-03	0.168000	2.95e-02
Intra-Golgi and retrograde Golgi-to-ER traffic	178	4.41e-03	0.124000	2.96e-02
Dissolution of Fibrin Clot	12	4.52e-03	0.473000	3.00e-02
Transmission across Chemical Synapses	194	4.52e-03	0.118000	3.00e-02
Keratan sulfate biosynthesis	27	4.52e-03	0.316000	3.00e-02
Transport of Mature mRNA Derived from an Intronless Transcript	42	4.55e-03	-0.253000	3.00e-02
RNA Polymerase II Transcription Termination	65	4.58e-03	-0.203000	3.01e-02
Constitutive Signaling by NOTCH1 HD Domain Mutants	15	4.68e-03	0.422000	3.05e-02
Signaling by NOTCH1 HD Domain Mutants in Cancer	15	4.68e-03	0.422000	3.05e-02
Metal ion SLC transporters	22	4.77e-03	0.348000	3.09e-02
Transcription of E2F targets under negative control by DREAM complex	19	4.86e-03	-0.373000	3.13e-02
Hemostasis	580	5.01e-03	-0.068300	3.22e-02
Mitotic Anaphase	224	5.10e-03	-0.109000	3.26e-02
Downregulation of TGF-beta receptor signaling	26	5.20e-03	0.317000	3.31e-02
EML4 and NUDC in mitotic spindle formation	96	5.33e-03	-0.165000	3.38e-02
SUMOylation of DNA replication proteins	46	5.40e-03	-0.237000	3.41e-02
Defective B4GALT7 causes EDS, progeroid type	17	5.50e-03	0.389000	3.46e-02
Regulation of TP53 Activity	154	5.98e-03	-0.128000	3.74e-02
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling	25	6.14e-03	0.317000	3.80e-02
Circadian Clock	67	6.20e-03	0.193000	3.80e-02
Insulin receptor recycling	23	6.22e-03	0.330000	3.80e-02
Telomere Maintenance	80	6.22e-03	-0.177000	3.80e-02
Leading Strand Synthesis	14	6.24e-03	-0.422000	3.80e-02
Polymerase switching	14	6.24e-03	-0.422000	3.80e-02
Deposition of new CENPA-containing nucleosomes at the centromere	40	6.33e-03	-0.249000	3.83e-02
Nucleosome assembly	40	6.33e-03	-0.249000	3.83e-02
Regulation of TP53 Activity through Phosphorylation	89	6.41e-03	-0.167000	3.86e-02
Generation of second messenger molecules	33	6.43e-03	-0.274000	3.86e-02
Crosslinking of collagen fibrils	10	6.56e-03	0.496000	3.92e-02
Laminin interactions	23	6.77e-03	0.326000	4.02e-02
Signaling by NOTCH2	32	6.79e-03	0.276000	4.02e-02
VEGFA-VEGFR2 Pathway	94	6.92e-03	0.161000	4.08e-02
Nephrin family interactions	21	6.99e-03	0.340000	4.11e-02
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1	16	7.05e-03	-0.389000	4.11e-02
A tetrasaccharide linker sequence is required for GAG synthesis	23	7.06e-03	0.324000	4.11e-02
G2/M DNA damage checkpoint	67	7.09e-03	-0.190000	4.12e-02
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)	14	7.51e-03	-0.413000	4.34e-02
Signaling by Interleukins	401	7.72e-03	0.077600	4.45e-02
EPH-Ephrin signaling	87	7.78e-03	0.165000	4.45e-02
Signaling by WNT	266	7.79e-03	0.094800	4.45e-02
YAP1- and WWTR1 (TAZ)-stimulated gene expression	11	7.97e-03	0.462000	4.54e-02
Transferrin endocytosis and recycling	29	8.05e-03	0.284000	4.56e-02
Metabolism of carbohydrates	264	8.10e-03	0.094700	4.57e-02
Signaling by FGFR3	35	8.17e-03	0.258000	4.60e-02
Activation of SMO	17	8.28e-03	0.370000	4.64e-02
Metabolism of nitric oxide: NOS3 activation and regulation	15	8.36e-03	0.393000	4.65e-02
Elastic fibre formation	37	8.36e-03	0.251000	4.65e-02
Base Excision Repair	59	8.55e-03	-0.198000	4.71e-02
Eicosanoid ligand-binding receptors	15	8.55e-03	-0.392000	4.71e-02
Transport of bile salts and organic acids, metal ions and amine compounds	58	8.57e-03	0.200000	4.71e-02
Defective B3GAT3 causes JDSSDHD	17	8.68e-03	0.368000	4.76e-02
Signaling by ALK fusions and activated point mutants	54	8.96e-03	0.206000	4.87e-02
Signaling by ALK in cancer	54	8.96e-03	0.206000	4.87e-02
G alpha (12/13) signalling events	73	9.18e-03	0.176000	4.97e-02
Response to metal ions	10	9.24e-03	0.475000	4.98e-02
Hedgehog ‘on’ state	83	9.70e-03	0.164000	5.21e-02
Centrosome maturation	80	1.01e-02	-0.166000	5.39e-02
Recruitment of mitotic centrosome proteins and complexes	80	1.01e-02	-0.166000	5.39e-02
Interferon gamma signaling	86	1.02e-02	0.160000	5.39e-02
Sema4D in semaphorin signaling	24	1.02e-02	0.303000	5.39e-02
eNOS activation	11	1.03e-02	0.447000	5.42e-02
Signaling by Nuclear Receptors	232	1.03e-02	0.097800	5.42e-02
Iron uptake and transport	56	1.06e-02	0.197000	5.55e-02
Cyclin A/B1/B2 associated events during G2/M transition	25	1.07e-02	-0.295000	5.56e-02
Golgi-to-ER retrograde transport	111	1.09e-02	0.140000	5.68e-02
Transcriptional regulation by RUNX3	95	1.10e-02	0.151000	5.68e-02
Heparan sulfate/heparin (HS-GAG) metabolism	44	1.13e-02	0.221000	5.85e-02
Class A/1 (Rhodopsin-like receptors)	192	1.17e-02	-0.105000	6.02e-02
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)	14	1.17e-02	-0.389000	6.02e-02
Unblocking of NMDA receptors, glutamate binding and activation	19	1.19e-02	0.333000	6.06e-02
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)	26	1.20e-02	-0.285000	6.11e-02
Processive synthesis on the C-strand of the telomere	19	1.20e-02	-0.333000	6.11e-02
Regulation of RUNX2 expression and activity	71	1.22e-02	0.172000	6.19e-02
TGF-beta receptor signaling activates SMADs	32	1.23e-02	0.256000	6.20e-02
HDR through Single Strand Annealing (SSA)	37	1.25e-02	-0.237000	6.27e-02
MET promotes cell motility	28	1.26e-02	0.272000	6.30e-02
Mismatch Repair	15	1.30e-02	-0.370000	6.47e-02
Ion channel transport	145	1.33e-02	0.119000	6.60e-02
GABA receptor activation	40	1.33e-02	0.226000	6.61e-02
Signaling by EGFR	49	1.40e-02	0.203000	6.90e-02
MAPK1/MAPK3 signaling	253	1.40e-02	0.089700	6.90e-02
Protein-protein interactions at synapses	72	1.43e-02	0.167000	7.01e-02
Separation of Sister Chromatids	168	1.45e-02	-0.109000	7.10e-02
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand	37	1.47e-02	0.232000	7.14e-02
Smooth Muscle Contraction	33	1.48e-02	0.245000	7.19e-02
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest	18	1.49e-02	-0.332000	7.19e-02
RHOV GTPase cycle	36	1.51e-02	0.234000	7.27e-02
ESR-mediated signaling	165	1.52e-02	0.110000	7.31e-02
Diseases of DNA repair	34	1.53e-02	-0.240000	7.31e-02
Resolution of Abasic Sites (AP sites)	38	1.53e-02	-0.227000	7.31e-02
RAF/MAP kinase cascade	247	1.54e-02	0.089500	7.34e-02
Signaling by Rho GTPases	619	1.57e-02	0.056900	7.46e-02
Mitotic G2-G2/M phases	182	1.61e-02	-0.103000	7.60e-02
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	14	1.66e-02	-0.370000	7.81e-02
Estrogen-dependent nuclear events downstream of ESR-membrane signaling	23	1.67e-02	0.288000	7.83e-02
Endogenous sterols	22	1.68e-02	0.294000	7.87e-02
Activation of GABAB receptors	32	1.71e-02	0.244000	7.95e-02
GABA B receptor activation	32	1.71e-02	0.244000	7.95e-02
TP53 Regulates Transcription of Cell Cycle Genes	48	1.73e-02	-0.199000	8.01e-02
Signaling by EGFR in Cancer	24	1.74e-02	0.280000	8.05e-02
Transport of the SLBP Dependant Mature mRNA	36	1.82e-02	-0.227000	8.40e-02
Reproduction	76	1.84e-02	-0.156000	8.44e-02
Defective EXT1 causes exostoses 1, TRPS2 and CHDS	14	1.88e-02	0.363000	8.55e-02
Defective EXT2 causes exostoses 2	14	1.88e-02	0.363000	8.55e-02
Rev-mediated nuclear export of HIV RNA	35	1.88e-02	-0.229000	8.55e-02
Activated NOTCH1 Transmits Signal to the Nucleus	30	1.91e-02	0.247000	8.67e-02
Switching of origins to a post-replicative state	89	1.93e-02	-0.144000	8.70e-02
Tight junction interactions	18	1.94e-02	0.318000	8.73e-02
AURKA Activation by TPX2	71	1.95e-02	-0.160000	8.75e-02
Recruitment of NuMA to mitotic centrosomes	79	1.95e-02	-0.152000	8.75e-02
Signal amplification	28	1.99e-02	0.254000	8.91e-02
RAC1 GTPase cycle	179	2.02e-02	0.101000	8.98e-02
MAPK6/MAPK4 signaling	85	2.03e-02	0.146000	8.99e-02
Signaling by TGF-beta Receptor Complex	74	2.05e-02	0.156000	9.06e-02
Receptor-type tyrosine-protein phosphatases	15	2.14e-02	0.343000	9.42e-02
E2F mediated regulation of DNA replication	22	2.16e-02	-0.283000	9.51e-02
EPH-ephrin mediated repulsion of cells	45	2.21e-02	0.197000	9.61e-02
G alpha (z) signalling events	39	2.21e-02	0.212000	9.61e-02
Signaling by FGFR3 in disease	17	2.21e-02	0.321000	9.61e-02
Signaling by FGFR3 point mutants in cancer	17	2.21e-02	0.321000	9.61e-02
O-linked glycosylation of mucins	48	2.24e-02	0.191000	9.70e-02
Glutamate binding, activation of AMPA receptors and synaptic plasticity	28	2.27e-02	0.249000	9.76e-02
Trafficking of AMPA receptors	28	2.27e-02	0.249000	9.76e-02
Reduction of cytosolic Ca++ levels	10	2.27e-02	0.416000	9.76e-02
Hedgehog ‘off’ state	96	2.32e-02	0.134000	9.91e-02
MAPK targets/ Nuclear events mediated by MAP kinases	31	2.35e-02	0.235000	1.00e-01
Platelet homeostasis	74	2.36e-02	0.152000	1.00e-01
Degradation of the extracellular matrix	94	2.36e-02	0.135000	1.00e-01
Translocation of ZAP-70 to Immunological synapse	19	2.37e-02	-0.300000	1.00e-01
Signaling by Insulin receptor	66	2.39e-02	0.161000	1.01e-01
Glucagon signaling in metabolic regulation	27	2.41e-02	0.251000	1.01e-01
Organelle biogenesis and maintenance	269	2.46e-02	0.079700	1.03e-01
Activation of G protein gated Potassium channels	20	2.50e-02	0.289000	1.04e-01
G protein gated Potassium channels	20	2.50e-02	0.289000	1.04e-01
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	20	2.50e-02	0.289000	1.04e-01
Signaling by NTRK3 (TRKC)	17	2.56e-02	0.313000	1.06e-01
Signaling by Rho GTPases, Miro GTPases and RHOBTB3	635	2.56e-02	0.052000	1.06e-01
MET activates PTK2 signaling	18	2.59e-02	0.303000	1.06e-01
Adrenaline,noradrenaline inhibits insulin secretion	24	2.59e-02	0.263000	1.06e-01
Oncogenic MAPK signaling	75	2.61e-02	0.149000	1.06e-01
Signaling by FGFR2	62	2.61e-02	0.163000	1.06e-01
ADP signalling through P2Y purinoceptor 1	21	2.62e-02	0.280000	1.06e-01
Phosphorylation of CD3 and TCR zeta chains	22	2.64e-02	-0.273000	1.06e-01
Meiotic recombination	38	2.65e-02	-0.208000	1.06e-01
Defective HDR through Homologous Recombination (HRR) due to BRCA1 loss-of-function	24	2.66e-02	-0.262000	1.06e-01
Defective HDR through Homologous Recombination (HRR) due to PALB2 loss of function	24	2.66e-02	-0.262000	1.06e-01
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function	24	2.66e-02	-0.262000	1.06e-01
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function	24	2.66e-02	-0.262000	1.06e-01
Diseases of DNA Double-Strand Break Repair	24	2.66e-02	-0.262000	1.06e-01
RHO GTPases Activate Formins	119	2.66e-02	-0.118000	1.06e-01
G2/M Transition	180	2.66e-02	-0.095800	1.06e-01
RHOQ GTPase cycle	58	2.68e-02	0.168000	1.06e-01
Vasopressin regulates renal water homeostasis via Aquaporins	34	2.68e-02	0.219000	1.06e-01
EGR2 and SOX10-mediated initiation of Schwann cell myelination	24	2.68e-02	0.261000	1.06e-01
Polymerase switching on the C-strand of the telomere	26	2.74e-02	-0.250000	1.08e-01
Downstream signaling of activated FGFR3	20	2.77e-02	0.284000	1.09e-01
Thromboxane signalling through TP receptor	20	2.79e-02	0.284000	1.09e-01
Signaling by FGFR3 fusions in cancer	10	2.79e-02	0.401000	1.09e-01
Transport of the SLBP independent Mature mRNA	35	2.81e-02	-0.215000	1.09e-01
WNT ligand biogenesis and trafficking	20	2.85e-02	0.283000	1.10e-01
Assembly of the pre-replicative complex	84	2.85e-02	-0.138000	1.10e-01
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS)	12	2.89e-02	-0.364000	1.11e-01
Diseases of hemostasis	12	2.89e-02	-0.364000	1.11e-01
Interactions of Rev with host cellular proteins	37	2.93e-02	-0.207000	1.12e-01
Downregulation of SMAD2/3:SMAD4 transcriptional activity	27	2.94e-02	0.242000	1.12e-01
Transport of Ribonucleoproteins into the Host Nucleus	32	2.95e-02	-0.222000	1.12e-01
Olfactory Signaling Pathway	14	2.96e-02	-0.336000	1.13e-01
Vpr-mediated nuclear import of PICs	34	3.00e-02	-0.215000	1.14e-01
mRNA Splicing - Major Pathway	179	3.01e-02	-0.094000	1.14e-01
E3 ubiquitin ligases ubiquitinate target proteins	51	3.02e-02	0.175000	1.14e-01
Post NMDA receptor activation events	56	3.05e-02	0.167000	1.15e-01
DAG and IP3 signaling	38	3.10e-02	0.202000	1.16e-01
Mitochondrial translation	96	3.14e-02	0.127000	1.18e-01
Ion homeostasis	46	3.14e-02	0.183000	1.18e-01
Pyrimidine salvage	10	3.19e-02	-0.392000	1.19e-01
NEP/NS2 Interacts with the Cellular Export Machinery	32	3.27e-02	-0.218000	1.22e-01
Signaling by PDGF	50	3.28e-02	0.174000	1.22e-01
Disease	1501	3.32e-02	0.033000	1.23e-01
Mitochondrial translation initiation	90	3.32e-02	0.130000	1.23e-01
Gap-filling DNA repair synthesis and ligation in GG-NER	25	3.36e-02	-0.245000	1.24e-01
Sema4D induced cell migration and growth-cone collapse	20	3.37e-02	0.274000	1.24e-01
Mitochondrial translation termination	90	3.39e-02	0.129000	1.24e-01
mRNA Splicing	187	3.44e-02	-0.089700	1.26e-01
Metabolism of RNA	681	3.51e-02	0.047400	1.28e-01
Export of Viral Ribonucleoproteins from Nucleus	33	3.54e-02	-0.212000	1.28e-01
Chromatin modifying enzymes	218	3.54e-02	-0.082700	1.28e-01
Chromatin organization	218	3.54e-02	-0.082700	1.28e-01
Loss of Nlp from mitotic centrosomes	68	3.59e-02	-0.147000	1.29e-01
Loss of proteins required for interphase microtubule organization from the centrosome	68	3.59e-02	-0.147000	1.29e-01
STAT5 activation downstream of FLT3 ITD mutants	10	3.61e-02	-0.383000	1.30e-01
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases	14	3.68e-02	0.322000	1.32e-01
NRAGE signals death through JNK	58	3.70e-02	0.158000	1.32e-01
Activation of BAD and translocation to mitochondria	15	3.75e-02	0.310000	1.34e-01
BBSome-mediated cargo-targeting to cilium	21	3.80e-02	0.262000	1.35e-01
Removal of the Flap Intermediate from the C-strand	17	3.85e-02	-0.290000	1.36e-01
Selective autophagy	58	3.87e-02	0.157000	1.36e-01
DNA Damage/Telomere Stress Induced Senescence	44	3.87e-02	-0.180000	1.36e-01
Cristae formation	31	3.88e-02	0.214000	1.36e-01
Signaling by FGFR4	35	3.88e-02	0.202000	1.36e-01
Activation of kainate receptors upon glutamate binding	26	3.91e-02	0.234000	1.37e-01
HS-GAG biosynthesis	25	3.93e-02	0.238000	1.38e-01
Condensation of Prophase Chromosomes	28	3.97e-02	-0.225000	1.38e-01
Generic Transcription Pathway	1125	3.97e-02	0.036400	1.38e-01
Erythrocytes take up carbon dioxide and release oxygen	12	4.05e-02	-0.342000	1.40e-01
O2/CO2 exchange in erythrocytes	12	4.05e-02	-0.342000	1.40e-01
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	33	4.05e-02	0.206000	1.40e-01
Class I MHC mediated antigen processing & presentation	358	4.11e-02	0.062900	1.42e-01
Protein ubiquitination	71	4.12e-02	0.140000	1.42e-01
Condensation of Prometaphase Chromosomes	11	4.15e-02	-0.355000	1.42e-01
PINK1-PRKN Mediated Mitophagy	21	4.23e-02	0.256000	1.45e-01
Signaling by FGFR2 in disease	35	4.25e-02	0.198000	1.45e-01
Signaling by FGFR2 IIIa TM	19	4.26e-02	0.269000	1.45e-01
Formation of ATP by chemiosmotic coupling	18	4.27e-02	0.276000	1.45e-01
Downstream signal transduction	28	4.29e-02	0.221000	1.46e-01
PLC beta mediated events	46	4.32e-02	0.172000	1.46e-01
Aquaporin-mediated transport	37	4.37e-02	0.192000	1.48e-01
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template	38	4.40e-02	-0.189000	1.48e-01
Nuclear Pore Complex (NPC) Disassembly	36	4.45e-02	-0.194000	1.49e-01
Interleukin-6 signaling	11	4.47e-02	0.350000	1.50e-01
Thrombin signalling through proteinase activated receptors (PARs)	26	4.48e-02	0.227000	1.50e-01
Nuclear Envelope Breakdown	53	4.48e-02	-0.159000	1.50e-01
SUMOylation of ubiquitinylation proteins	39	4.53e-02	-0.185000	1.51e-01
Processing of Intronless Pre-mRNAs	19	4.54e-02	-0.265000	1.51e-01
DNA Damage Bypass	47	4.68e-02	-0.168000	1.55e-01
Nuclear import of Rev protein	34	4.69e-02	-0.197000	1.55e-01
G-protein mediated events	50	4.72e-02	0.162000	1.55e-01
G alpha (q) signalling events	152	4.72e-02	0.093300	1.55e-01
Mitochondrial translation elongation	90	4.77e-02	0.121000	1.57e-01
SLC-mediated transmembrane transport	187	4.82e-02	0.083800	1.58e-01
Antigen processing: Ubiquitination & Proteasome degradation	293	4.94e-02	0.066800	1.61e-01
Glutamate Neurotransmitter Release Cycle	23	4.95e-02	0.237000	1.61e-01
Orc1 removal from chromatin	69	4.96e-02	-0.137000	1.61e-01
Serotonin Neurotransmitter Release Cycle	17	4.98e-02	0.275000	1.62e-01
Gap junction trafficking and regulation	19	5.03e-02	0.259000	1.63e-01
Downstream signaling of activated FGFR1	24	5.08e-02	0.230000	1.64e-01
Cell death signalling via NRAGE, NRIF and NADE	75	5.10e-02	0.130000	1.64e-01
RAF-independent MAPK1/3 activation	22	5.11e-02	0.240000	1.64e-01
Recognition of DNA damage by PCNA-containing replication complex	30	5.15e-02	-0.205000	1.65e-01
Meiosis	66	5.16e-02	-0.139000	1.65e-01
RET signaling	35	5.16e-02	0.190000	1.65e-01
Translocation of SLC2A4 (GLUT4) to the plasma membrane	50	5.23e-02	0.159000	1.66e-01
Neddylation	222	5.23e-02	0.075600	1.66e-01
Negative regulation of NMDA receptor-mediated neuronal transmission	18	5.34e-02	0.263000	1.70e-01
Norepinephrine Neurotransmitter Release Cycle	16	5.40e-02	0.278000	1.71e-01
Molecules associated with elastic fibres	27	5.42e-02	0.214000	1.71e-01
tRNA processing	130	5.47e-02	0.097600	1.72e-01
Immune System	1823	5.48e-02	-0.027200	1.73e-01
TP53 Regulates Transcription of Caspase Activators and Caspases	12	5.50e-02	-0.320000	1.73e-01
RHOBTB GTPase Cycle	35	5.65e-02	0.186000	1.77e-01
CDC42 GTPase cycle	151	5.81e-02	0.089400	1.82e-01
HSF1-dependent transactivation	32	5.88e-02	0.193000	1.83e-01
Signaling by WNT in cancer	32	5.89e-02	0.193000	1.83e-01
Dopamine Neurotransmitter Release Cycle	22	6.01e-02	0.232000	1.87e-01
CREB1 phosphorylation through the activation of Adenylate Cyclase	10	6.07e-02	0.343000	1.88e-01
Death Receptor Signalling	138	6.13e-02	0.092300	1.89e-01
Acetylcholine Neurotransmitter Release Cycle	13	6.13e-02	0.300000	1.89e-01
Nucleotide salvage	22	6.25e-02	-0.229000	1.93e-01
NOTCH4 Intracellular Domain Regulates Transcription	19	6.30e-02	0.246000	1.94e-01
COPI-independent Golgi-to-ER retrograde traffic	33	6.34e-02	0.187000	1.95e-01
Platelet calcium homeostasis	23	6.45e-02	0.223000	1.97e-01
Peptide ligand-binding receptors	112	6.49e-02	-0.101000	1.98e-01
DARPP-32 events	23	6.51e-02	0.222000	1.98e-01
Inwardly rectifying K+ channels	25	6.57e-02	0.213000	2.00e-01
Glucagon-type ligand receptors	23	6.59e-02	0.222000	2.00e-01
Termination of translesion DNA synthesis	32	6.60e-02	-0.188000	2.00e-01
Translesion synthesis by REV1	16	6.63e-02	-0.265000	2.00e-01
NOTCH4 Activation and Transmission of Signal to the Nucleus	11	6.68e-02	0.319000	2.01e-01
Response to elevated platelet cytosolic Ca2+	119	6.68e-02	0.097300	2.01e-01
Signaling by MET	65	6.75e-02	0.131000	2.03e-01
Signaling by NOTCH3	47	6.76e-02	0.154000	2.03e-01
COPI-dependent Golgi-to-ER retrograde traffic	78	6.80e-02	0.120000	2.03e-01
SHC-mediated cascade:FGFR3	13	6.80e-02	0.292000	2.03e-01
Downstream signaling of activated FGFR2	22	6.83e-02	0.224000	2.04e-01
The canonical retinoid cycle in rods (twilight vision)	14	6.91e-02	-0.281000	2.05e-01
PI-3K cascade:FGFR3	13	6.92e-02	0.291000	2.05e-01
Toll Like Receptor 9 (TLR9) Cascade	94	6.95e-02	0.108000	2.06e-01
Platelet degranulation	115	7.10e-02	0.097500	2.10e-01
Intracellular signaling by second messengers	292	7.22e-02	0.061200	2.13e-01
p75 NTR receptor-mediated signalling	94	7.25e-02	0.107000	2.13e-01
SHC1 events in EGFR signaling	13	7.30e-02	0.287000	2.14e-01
Attenuation phase	22	7.35e-02	0.220000	2.15e-01
Interleukin-2 signaling	11	7.35e-02	-0.312000	2.15e-01
Aberrant regulation of mitotic cell cycle due to RB1 defects	36	7.39e-02	-0.172000	2.16e-01
Methylation	13	7.58e-02	0.284000	2.21e-01
Cilium Assembly	179	7.63e-02	0.076800	2.22e-01
Cytosolic iron-sulfur cluster assembly	13	7.64e-02	-0.284000	2.22e-01
Arachidonic acid metabolism	45	7.77e-02	-0.152000	2.25e-01
Translesion synthesis by POLI	17	7.83e-02	-0.247000	2.25e-01
NS1 Mediated Effects on Host Pathways	40	7.84e-02	-0.161000	2.25e-01
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants	57	7.88e-02	0.135000	2.25e-01
Constitutive Signaling by NOTCH1 PEST Domain Mutants	57	7.88e-02	0.135000	2.25e-01
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer	57	7.88e-02	0.135000	2.25e-01
Signaling by NOTCH1 PEST Domain Mutants in Cancer	57	7.88e-02	0.135000	2.25e-01
Signaling by NOTCH1 in Cancer	57	7.88e-02	0.135000	2.25e-01
Anchoring of the basal body to the plasma membrane	96	7.89e-02	-0.104000	2.25e-01
Sphingolipid metabolism	80	7.99e-02	0.113000	2.27e-01
RHOG GTPase cycle	73	8.14e-02	0.118000	2.31e-01
RND2 GTPase cycle	39	8.18e-02	0.161000	2.32e-01
ADORA2B mediated anti-inflammatory cytokines production	78	8.24e-02	0.114000	2.32e-01
Activation of Ca-permeable Kainate Receptor	10	8.25e-02	0.317000	2.32e-01
Ionotropic activity of kainate receptors	10	8.25e-02	0.317000	2.32e-01
GP1b-IX-V activation signalling	10	8.29e-02	-0.317000	2.33e-01
Downstream signaling of activated FGFR4	21	8.33e-02	0.218000	2.33e-01
Plasma lipoprotein assembly	12	8.33e-02	0.289000	2.33e-01
HATs acetylate histones	93	8.51e-02	-0.103000	2.38e-01
Mitotic Prophase	97	8.51e-02	-0.101000	2.38e-01
PD-1 signaling	23	8.64e-02	-0.207000	2.41e-01
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	52	8.68e-02	-0.137000	2.41e-01
Apoptotic factor-mediated response	20	8.70e-02	0.221000	2.41e-01
Processing of Capped Intronless Pre-mRNA	28	8.78e-02	-0.186000	2.43e-01
Signaling by FGFR4 in disease	11	8.82e-02	0.297000	2.44e-01
SUMOylation of SUMOylation proteins	35	8.87e-02	-0.166000	2.44e-01
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha	64	8.88e-02	0.123000	2.44e-01
Negative regulation of FGFR3 signaling	24	8.99e-02	0.200000	2.47e-01
Constitutive Signaling by Overexpressed ERBB2	11	9.01e-02	0.295000	2.47e-01
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	16	9.04e-02	0.244000	2.47e-01
Defective pyroptosis	28	9.05e-02	-0.185000	2.47e-01
ERK/MAPK targets	22	9.09e-02	0.208000	2.47e-01
Programmed Cell Death	198	9.10e-02	0.069700	2.47e-01
Signaling by NOTCH4	81	9.11e-02	0.109000	2.47e-01
RHO GTPase Effectors	253	9.12e-02	-0.061700	2.47e-01
Other semaphorin interactions	19	9.14e-02	0.224000	2.48e-01
Gap junction trafficking	17	9.22e-02	0.236000	2.49e-01
TP53 Regulates Metabolic Genes	85	9.27e-02	0.105000	2.49e-01
Activation of NMDA receptors and postsynaptic events	68	9.31e-02	0.118000	2.49e-01
Signaling by PDGFRA extracellular domain mutants	12	9.31e-02	0.280000	2.49e-01
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants	12	9.31e-02	0.280000	2.49e-01
Pre-NOTCH Processing in Golgi	18	9.31e-02	0.229000	2.49e-01
Downstream signaling events of B Cell Receptor (BCR)	79	9.35e-02	0.109000	2.49e-01
EPHB-mediated forward signaling	33	9.39e-02	0.169000	2.49e-01
Regulation of PLK1 Activity at G2/M Transition	86	9.39e-02	-0.105000	2.49e-01
NOTCH3 Activation and Transmission of Signal to the Nucleus	25	9.40e-02	0.194000	2.49e-01
PCP/CE pathway	89	9.40e-02	0.103000	2.49e-01
Signaling by CSF3 (G-CSF)	30	9.42e-02	0.177000	2.49e-01
Signaling by FGFR in disease	55	9.46e-02	0.130000	2.50e-01
G-protein activation	19	9.50e-02	0.221000	2.51e-01
Platelet activation, signaling and aggregation	235	9.53e-02	0.063200	2.51e-01
Signaling by GPCR	482	9.54e-02	0.044400	2.51e-01
Plasma lipoprotein assembly, remodeling, and clearance	56	9.55e-02	0.129000	2.51e-01
CTLA4 inhibitory signaling	20	9.60e-02	0.215000	2.52e-01
FOXO-mediated transcription of cell cycle genes	15	9.69e-02	0.248000	2.53e-01
RHOBTB2 GTPase cycle	23	9.73e-02	0.200000	2.54e-01
Diseases of programmed cell death	57	9.76e-02	-0.127000	2.54e-01
ALK mutants bind TKIs	11	9.85e-02	0.288000	2.56e-01
Nicotinamide salvaging	16	9.93e-02	0.238000	2.58e-01
Asymmetric localization of PCP proteins	62	9.95e-02	0.121000	2.58e-01
Diseases of mitotic cell cycle	38	9.97e-02	-0.154000	2.58e-01
Signal regulatory protein family interactions	12	1.01e-01	-0.273000	2.62e-01
ADP signalling through P2Y purinoceptor 12	17	1.02e-01	0.229000	2.62e-01
Regulation of localization of FOXO transcription factors	12	1.02e-01	0.273000	2.62e-01
Regulation of FZD by ubiquitination	19	1.02e-01	0.217000	2.62e-01
L1CAM interactions	93	1.02e-01	0.098100	2.62e-01
Metabolism of non-coding RNA	53	1.05e-01	-0.129000	2.68e-01
snRNP Assembly	53	1.05e-01	-0.129000	2.68e-01
RHO GTPases Activate NADPH Oxidases	21	1.05e-01	-0.204000	2.69e-01
PRC2 methylates histones and DNA	28	1.07e-01	-0.176000	2.71e-01
Cellular response to hypoxia	72	1.07e-01	0.110000	2.71e-01
Regulation of TP53 Activity through Acetylation	29	1.09e-01	-0.172000	2.75e-01
MyD88-independent TLR4 cascade	97	1.09e-01	0.094200	2.75e-01
TRIF(TICAM1)-mediated TLR4 signaling	97	1.09e-01	0.094200	2.75e-01
Mitochondrial protein import	64	1.10e-01	0.116000	2.77e-01
Gap-filling DNA repair synthesis and ligation in TC-NER	64	1.12e-01	-0.115000	2.81e-01
DNA Double Strand Break Response	50	1.12e-01	-0.130000	2.81e-01
MECP2 regulates neuronal receptors and channels	17	1.12e-01	0.222000	2.82e-01
Signaling by ERBB2 ECD mutants	16	1.13e-01	0.229000	2.82e-01
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)	32	1.13e-01	-0.162000	2.82e-01
Regulation of Glucokinase by Glucokinase Regulatory Protein	32	1.13e-01	-0.162000	2.82e-01
Fatty acid metabolism	154	1.14e-01	-0.073800	2.84e-01
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects	17	1.14e-01	-0.221000	2.84e-01
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)	17	1.14e-01	-0.221000	2.84e-01
Neurexins and neuroligins	47	1.15e-01	0.133000	2.85e-01
Long-term potentiation	21	1.15e-01	0.199000	2.85e-01
Signaling by NOTCH	188	1.15e-01	0.066600	2.85e-01
Presynaptic function of Kainate receptors	17	1.16e-01	0.220000	2.86e-01
Inactivation of CSF3 (G-CSF) signaling	25	1.16e-01	0.181000	2.87e-01
MyD88 dependent cascade initiated on endosome	90	1.17e-01	0.095500	2.89e-01
Signaling by NOTCH1	72	1.18e-01	0.107000	2.90e-01
Phase II - Conjugation of compounds	75	1.20e-01	0.104000	2.94e-01
Antiviral mechanism by IFN-stimulated genes	80	1.20e-01	0.101000	2.94e-01
Ephrin signaling	19	1.21e-01	0.206000	2.95e-01
Response of EIF2AK1 (HRI) to heme deficiency	15	1.21e-01	0.231000	2.96e-01
TCF dependent signaling in response to WNT	178	1.22e-01	0.067300	2.96e-01
Protein methylation	15	1.23e-01	0.230000	2.98e-01
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	14	1.23e-01	0.238000	2.98e-01
Interactions of Vpr with host cellular proteins	37	1.24e-01	-0.146000	2.99e-01
Integrin cell surface interactions	61	1.24e-01	0.114000	2.99e-01
Dual Incision in GG-NER	41	1.24e-01	-0.139000	2.99e-01
Phase 0 - rapid depolarisation	27	1.24e-01	0.171000	2.99e-01
Phase 2 - plateau phase	11	1.24e-01	-0.268000	2.99e-01
RHOU GTPase cycle	40	1.25e-01	0.140000	3.01e-01
Translesion synthesis by POLK	17	1.26e-01	-0.214000	3.02e-01
Antigen Presentation: Folding, assembly and peptide loading of class I MHC	25	1.27e-01	0.176000	3.04e-01
EPHA-mediated growth cone collapse	15	1.27e-01	0.228000	3.04e-01
PKA-mediated phosphorylation of CREB	18	1.28e-01	0.207000	3.06e-01
Deactivation of the beta-catenin transactivating complex	39	1.28e-01	0.141000	3.06e-01
RAF activation	34	1.28e-01	0.151000	3.06e-01
Regulation of RAS by GAPs	66	1.29e-01	0.108000	3.06e-01
Regulation of PTEN stability and activity	67	1.29e-01	0.107000	3.06e-01
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	49	1.30e-01	-0.125000	3.06e-01
PIWI-interacting RNA (piRNA) biogenesis	24	1.30e-01	0.179000	3.06e-01
Collagen degradation	35	1.30e-01	0.148000	3.06e-01
WNT5A-dependent internalization of FZD2, FZD5 and ROR2	13	1.31e-01	0.242000	3.08e-01
EGFR downregulation	30	1.32e-01	0.159000	3.10e-01
RHOC GTPase cycle	72	1.33e-01	0.103000	3.10e-01
RAC3 GTPase cycle	90	1.33e-01	0.091700	3.10e-01
Nitric oxide stimulates guanylate cyclase	19	1.33e-01	0.199000	3.10e-01
ERBB2 Regulates Cell Motility	14	1.33e-01	-0.232000	3.11e-01
Fertilization	10	1.34e-01	-0.273000	3.14e-01
Signaling by ERBB2	48	1.35e-01	0.125000	3.14e-01
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	89	1.36e-01	0.091600	3.15e-01
CLEC7A (Dectin-1) signaling	97	1.36e-01	0.087600	3.15e-01
Acetylcholine regulates insulin secretion	10	1.36e-01	0.272000	3.16e-01
Apoptosis	170	1.39e-01	0.065800	3.21e-01
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon	17	1.39e-01	0.207000	3.22e-01
GRB2 events in EGFR signaling	12	1.41e-01	0.245000	3.26e-01
Negative regulation of MAPK pathway	42	1.41e-01	0.131000	3.26e-01
Metalloprotease DUBs	22	1.42e-01	-0.181000	3.26e-01
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants	19	1.42e-01	0.194000	3.26e-01
Signaling by Ligand-Responsive EGFR Variants in Cancer	19	1.42e-01	0.194000	3.26e-01
Transcriptional regulation of granulopoiesis	45	1.43e-01	-0.126000	3.27e-01
Transcriptional regulation by small RNAs	62	1.45e-01	-0.107000	3.30e-01
Pyruvate metabolism	27	1.45e-01	0.162000	3.31e-01
Toll Like Receptor 7/8 (TLR7/8) Cascade	91	1.46e-01	0.088200	3.32e-01
Assembly of the ORC complex at the origin of replication	24	1.46e-01	-0.172000	3.32e-01
Cardiac conduction	100	1.46e-01	0.084100	3.32e-01
Epigenetic regulation of gene expression	102	1.46e-01	-0.083200	3.32e-01
PKA activation in glucagon signalling	15	1.47e-01	0.216000	3.33e-01
p130Cas linkage to MAPK signaling for integrins	12	1.48e-01	0.241000	3.34e-01
Mitophagy	28	1.48e-01	0.158000	3.35e-01
Cholesterol biosynthesis	24	1.49e-01	0.170000	3.36e-01
Telomere Extension By Telomerase	23	1.50e-01	-0.174000	3.37e-01
RHOJ GTPase cycle	54	1.50e-01	0.113000	3.37e-01
Transcriptional regulation of white adipocyte differentiation	84	1.50e-01	-0.090800	3.37e-01
Mitotic Telophase/Cytokinesis	13	1.51e-01	-0.230000	3.38e-01
TRAF6-mediated induction of TAK1 complex within TLR4 complex	16	1.52e-01	0.207000	3.40e-01
HCMV Early Events	74	1.53e-01	-0.096200	3.41e-01
APC/C-mediated degradation of cell cycle proteins	86	1.53e-01	-0.089100	3.41e-01
Regulation of mitotic cell cycle	86	1.53e-01	-0.089100	3.41e-01
RHOB GTPase cycle	68	1.55e-01	0.099600	3.45e-01
RHOBTB1 GTPase cycle	23	1.56e-01	0.171000	3.46e-01
Peroxisomal lipid metabolism	27	1.57e-01	-0.158000	3.46e-01
Nonhomologous End-Joining (NHEJ)	41	1.57e-01	-0.128000	3.46e-01
Interleukin-3, Interleukin-5 and GM-CSF signaling	40	1.57e-01	-0.129000	3.46e-01
Caspase activation via extrinsic apoptotic signalling pathway	25	1.58e-01	0.163000	3.48e-01
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	15	1.58e-01	0.211000	3.48e-01
Nuclear Envelope (NE) Reassembly	69	1.60e-01	-0.097900	3.51e-01
Nuclear events stimulated by ALK signaling in cancer	18	1.60e-01	0.191000	3.51e-01
FRS-mediated FGFR3 signaling	15	1.60e-01	0.209000	3.51e-01
Interleukin-2 family signaling	37	1.61e-01	-0.133000	3.52e-01
Keratinization	33	1.61e-01	0.141000	3.52e-01
Assembly of active LPL and LIPC lipase complexes	14	1.62e-01	0.216000	3.53e-01
tRNA processing in the nucleus	59	1.63e-01	-0.105000	3.56e-01
G beta:gamma signalling through BTK	14	1.63e-01	0.215000	3.56e-01
RNA Polymerase II Transcription	1243	1.64e-01	0.023500	3.56e-01
Signaling by Non-Receptor Tyrosine Kinases	52	1.64e-01	0.111000	3.56e-01
Signaling by PTK6	52	1.64e-01	0.111000	3.56e-01
Interleukin-27 signaling	10	1.67e-01	0.253000	3.60e-01
Negative regulation of FGFR2 signaling	26	1.69e-01	0.156000	3.65e-01
Mitochondrial biogenesis	90	1.69e-01	0.083900	3.65e-01
Signaling by NTRK2 (TRKB)	24	1.69e-01	0.162000	3.65e-01
DNA methylation	19	1.70e-01	-0.182000	3.65e-01
TNFR2 non-canonical NF-kB pathway	97	1.71e-01	0.080400	3.67e-01
G beta:gamma signalling through CDC42	16	1.71e-01	0.197000	3.67e-01
Phase I - Functionalization of compounds	76	1.72e-01	-0.090600	3.68e-01
SHC-mediated cascade:FGFR2	15	1.72e-01	0.204000	3.68e-01
Prostacyclin signalling through prostacyclin receptor	15	1.73e-01	0.203000	3.68e-01
Pyroptosis	26	1.74e-01	0.154000	3.70e-01
CRMPs in Sema3A signaling	15	1.74e-01	0.203000	3.70e-01
PI-3K cascade:FGFR2	15	1.74e-01	0.203000	3.71e-01
SUMOylation	168	1.76e-01	-0.060600	3.72e-01
Synthesis of active ubiquitin: roles of E1 and E2 enzymes	30	1.76e-01	0.143000	3.72e-01
Beta-oxidation of very long chain fatty acids	10	1.76e-01	-0.247000	3.72e-01
SUMO E3 ligases SUMOylate target proteins	162	1.76e-01	-0.061600	3.72e-01
Translesion Synthesis by POLH	18	1.76e-01	-0.184000	3.72e-01
Sensory processing of sound by inner hair cells of the cochlea	56	1.77e-01	0.104000	3.73e-01
Chemokine receptors bind chemokines	46	1.77e-01	-0.115000	3.73e-01
Amino acids regulate mTORC1	51	1.78e-01	0.109000	3.75e-01
Aggrephagy	21	1.79e-01	0.170000	3.75e-01
Viral Messenger RNA Synthesis	44	1.79e-01	-0.117000	3.75e-01
Intrinsic Pathway for Apoptosis	55	1.83e-01	0.104000	3.82e-01
Activation of RAC1	12	1.84e-01	0.222000	3.83e-01
Synthesis of PIPs at the late endosome membrane	11	1.85e-01	0.231000	3.85e-01
Plasma lipoprotein remodeling	22	1.89e-01	0.162000	3.94e-01
Synthesis of very long-chain fatty acyl-CoAs	21	1.90e-01	-0.165000	3.95e-01
Cytochrome P450 - arranged by substrate type	41	1.94e-01	0.117000	4.02e-01
Constitutive Signaling by EGFRvIII	15	1.97e-01	0.193000	4.07e-01
Signaling by EGFRvIII in Cancer	15	1.97e-01	0.193000	4.07e-01
Disassembly of the destruction complex and recruitment of AXIN to the membrane	28	1.97e-01	0.141000	4.08e-01
Transcription-Coupled Nucleotide Excision Repair (TC-NER)	78	1.98e-01	-0.084400	4.08e-01
Glycogen synthesis	15	1.98e-01	0.192000	4.08e-01
Toll Like Receptor 3 (TLR3) Cascade	93	1.99e-01	0.077100	4.09e-01
GPVI-mediated activation cascade	32	2.00e-01	-0.131000	4.11e-01
RAS processing	19	2.00e-01	0.170000	4.11e-01
Negative regulation of FGFR4 signaling	25	2.00e-01	0.148000	4.11e-01
Signaling by KIT in disease	20	2.01e-01	0.165000	4.11e-01
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants	20	2.01e-01	0.165000	4.11e-01
Nucleotide Excision Repair	110	2.02e-01	-0.070500	4.12e-01
ERBB2 Activates PTK6 Signaling	12	2.03e-01	-0.212000	4.13e-01
Biosynthesis of DHA-derived SPMs	15	2.03e-01	-0.190000	4.13e-01
HCMV Late Events	70	2.04e-01	-0.087800	4.14e-01
Synthesis of PIPs at the early endosome membrane	16	2.05e-01	0.183000	4.15e-01
FOXO-mediated transcription of cell death genes	16	2.07e-01	-0.182000	4.20e-01
RHO GTPases Activate ROCKs	19	2.08e-01	0.167000	4.20e-01
Cytochrome c-mediated apoptotic response	13	2.08e-01	0.202000	4.20e-01
G beta:gamma signalling through PLC beta	16	2.09e-01	0.181000	4.22e-01
Retrograde transport at the Trans-Golgi-Network	49	2.09e-01	0.104000	4.22e-01
Glycosphingolipid metabolism	39	2.10e-01	0.116000	4.23e-01
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer	45	2.11e-01	0.108000	4.24e-01
SHC-mediated cascade:FGFR4	14	2.12e-01	0.193000	4.24e-01
Lewis blood group biosynthesis	13	2.12e-01	0.200000	4.24e-01
Ca-dependent events	34	2.12e-01	0.124000	4.24e-01
Assembly and cell surface presentation of NMDA receptors	23	2.12e-01	0.150000	4.24e-01
Inhibition of replication initiation of damaged DNA by RB1/E2F1	13	2.14e-01	-0.199000	4.27e-01
PI-3K cascade:FGFR4	14	2.14e-01	0.192000	4.27e-01
Regulated Necrosis	55	2.15e-01	0.096700	4.27e-01
Signaling by ERBB4	52	2.15e-01	0.099500	4.27e-01
HDACs deacetylate histones	46	2.16e-01	-0.105000	4.28e-01
RIP-mediated NFkB activation via ZBP1	17	2.16e-01	-0.173000	4.28e-01
BMAL1:CLOCK,NPAS2 activates circadian gene expression	25	2.16e-01	0.143000	4.28e-01
Amino acid transport across the plasma membrane	26	2.16e-01	-0.140000	4.28e-01
Biosynthesis of specialized proresolving mediators (SPMs)	17	2.19e-01	-0.172000	4.33e-01
Regulation of cholesterol biosynthesis by SREBP (SREBF)	55	2.20e-01	0.095600	4.34e-01
Phosphorylation of the APC/C	20	2.20e-01	-0.158000	4.34e-01
Inactivation of APC/C via direct inhibition of the APC/C complex	21	2.21e-01	-0.154000	4.34e-01
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components	21	2.21e-01	-0.154000	4.34e-01
Sphingolipid de novo biosynthesis	41	2.22e-01	0.110000	4.35e-01
Transcriptional Regulation by TP53	352	2.24e-01	-0.037800	4.38e-01
Cytoprotection by HMOX1	119	2.24e-01	0.064500	4.38e-01
Glycogen metabolism	26	2.27e-01	0.137000	4.43e-01
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression	31	2.28e-01	-0.125000	4.44e-01
MAP kinase activation	63	2.31e-01	0.087300	4.49e-01
Mucopolysaccharidoses	11	2.31e-01	0.209000	4.49e-01
Negative regulation of FGFR1 signaling	26	2.31e-01	0.136000	4.49e-01
Post-translational modification: synthesis of GPI-anchored proteins	68	2.32e-01	0.083900	4.49e-01
RHOF GTPase cycle	41	2.32e-01	0.108000	4.49e-01
Regulation of FOXO transcriptional activity by acetylation	10	2.32e-01	-0.218000	4.49e-01
Transcriptional Regulation by E2F6	34	2.36e-01	-0.118000	4.55e-01
Dual incision in TC-NER	65	2.37e-01	-0.084900	4.56e-01
Miscellaneous transport and binding events	23	2.37e-01	0.142000	4.56e-01
Neurotransmitter release cycle	42	2.37e-01	0.105000	4.56e-01
FGFR2 mutant receptor activation	25	2.39e-01	0.136000	4.59e-01
Trafficking of GluR2-containing AMPA receptors	16	2.39e-01	0.170000	4.60e-01
Dectin-1 mediated noncanonical NF-kB signaling	59	2.41e-01	0.088300	4.61e-01
Defects in cobalamin (B12) metabolism	13	2.41e-01	0.188000	4.61e-01
Scavenging by Class A Receptors	17	2.41e-01	0.164000	4.61e-01
NRIF signals cell death from the nucleus	16	2.42e-01	0.169000	4.62e-01
Synthesis, secretion, and deacylation of Ghrelin	15	2.43e-01	-0.174000	4.63e-01
PKA activation	16	2.44e-01	0.168000	4.63e-01
CaM pathway	32	2.44e-01	0.119000	4.63e-01
Calmodulin induced events	32	2.44e-01	0.119000	4.63e-01
RAC2 GTPase cycle	88	2.44e-01	0.071800	4.63e-01
Diseases associated with glycosylation precursor biosynthesis	18	2.45e-01	0.158000	4.63e-01
Defects in vitamin and cofactor metabolism	21	2.46e-01	0.146000	4.63e-01
Cleavage of the damaged purine	24	2.46e-01	-0.137000	4.63e-01
Depurination	24	2.46e-01	-0.137000	4.63e-01
Recognition and association of DNA glycosylase with site containing an affected purine	24	2.46e-01	-0.137000	4.63e-01
HS-GAG degradation	20	2.46e-01	0.150000	4.63e-01
ERKs are inactivated	13	2.48e-01	0.185000	4.66e-01
HDR through MMEJ (alt-NHEJ)	10	2.51e-01	-0.209000	4.72e-01
Formation of Senescence-Associated Heterochromatin Foci (SAHF)	13	2.54e-01	-0.183000	4.76e-01
C-type lectin receptors (CLRs)	127	2.55e-01	0.058500	4.77e-01
ZBP1(DAI) mediated induction of type I IFNs	20	2.57e-01	-0.146000	4.80e-01
PIP3 activates AKT signaling	255	2.58e-01	0.041100	4.82e-01
IKK complex recruitment mediated by RIP1	23	2.60e-01	0.136000	4.83e-01
MyD88 cascade initiated on plasma membrane	84	2.60e-01	0.071100	4.83e-01
Toll Like Receptor 10 (TLR10) Cascade	84	2.60e-01	0.071100	4.83e-01
Toll Like Receptor 5 (TLR5) Cascade	84	2.60e-01	0.071100	4.83e-01
SLC transporter disorders	76	2.60e-01	-0.074700	4.83e-01
SUMOylation of DNA damage response and repair proteins	77	2.61e-01	-0.074100	4.83e-01
Synthesis of IP3 and IP4 in the cytosol	24	2.61e-01	-0.133000	4.83e-01
Nucleotide biosynthesis	12	2.61e-01	-0.187000	4.83e-01
Chaperone Mediated Autophagy	19	2.62e-01	0.149000	4.84e-01
Dectin-2 family	17	2.65e-01	-0.156000	4.88e-01
STING mediated induction of host immune responses	15	2.67e-01	-0.165000	4.92e-01
Interleukin-15 signaling	14	2.70e-01	-0.170000	4.97e-01
Signaling by PDGFR in disease	20	2.71e-01	0.142000	4.97e-01
Aspartate and asparagine metabolism	11	2.71e-01	0.192000	4.97e-01
SUMOylation of RNA binding proteins	47	2.72e-01	-0.092700	4.97e-01
Peptide hormone metabolism	64	2.72e-01	0.079400	4.98e-01
Synthesis of PIPs at the plasma membrane	50	2.72e-01	0.089700	4.98e-01
HSF1 activation	25	2.74e-01	0.126000	5.00e-01
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	17	2.74e-01	0.153000	5.00e-01
Global Genome Nucleotide Excision Repair (GG-NER)	84	2.77e-01	-0.068600	5.05e-01
activated TAK1 mediates p38 MAPK activation	19	2.79e-01	-0.143000	5.07e-01
Citric acid cycle (TCA cycle)	22	2.80e-01	-0.133000	5.08e-01
Cytosolic sulfonation of small molecules	19	2.80e-01	0.143000	5.08e-01
Ion transport by P-type ATPases	47	2.82e-01	0.090700	5.11e-01
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	35	2.83e-01	0.105000	5.11e-01
Regulation of IFNA signaling	12	2.83e-01	0.179000	5.11e-01
Regulation of APC/C activators between G1/S and early anaphase	79	2.83e-01	-0.069900	5.11e-01
SUMOylation of intracellular receptors	28	2.84e-01	0.117000	5.11e-01
Signaling by FGFR1 in disease	33	2.85e-01	0.108000	5.12e-01
RNA Polymerase I Promoter Opening	18	2.85e-01	-0.146000	5.13e-01
Mitochondrial tRNA aminoacylation	21	2.86e-01	-0.135000	5.13e-01
Late endosomal microautophagy	31	2.87e-01	0.111000	5.14e-01
Assembly Of The HIV Virion	16	2.88e-01	0.153000	5.16e-01
Budding and maturation of HIV virion	28	2.90e-01	0.116000	5.18e-01
Gluconeogenesis	28	2.93e-01	0.115000	5.23e-01
PKMTs methylate histone lysines	44	2.93e-01	-0.091600	5.23e-01
p75NTR recruits signalling complexes	13	2.94e-01	0.168000	5.23e-01
Synaptic adhesion-like molecules	19	2.94e-01	0.139000	5.24e-01
Killing mechanisms	10	2.95e-01	0.191000	5.24e-01
WNT5:FZD7-mediated leishmania damping	10	2.95e-01	0.191000	5.24e-01
NOTCH3 Intracellular Domain Regulates Transcription	23	2.96e-01	0.126000	5.25e-01
G beta:gamma signalling through PI3Kgamma	21	2.98e-01	0.131000	5.28e-01
LGI-ADAM interactions	11	2.99e-01	-0.181000	5.28e-01
Signaling by BRAF and RAF1 fusions	59	3.00e-01	0.078100	5.29e-01
PI3K/AKT Signaling in Cancer	93	3.00e-01	0.062200	5.29e-01
Regulation of RUNX1 Expression and Activity	18	3.03e-01	0.140000	5.34e-01
Tie2 Signaling	17	3.03e-01	0.144000	5.34e-01
Suppression of phagosomal maturation	13	3.04e-01	0.165000	5.35e-01
Regulation of IFNG signaling	13	3.05e-01	0.164000	5.36e-01
RHO GTPases activate PKNs	49	3.05e-01	0.084600	5.36e-01
Formation of Fibrin Clot (Clotting Cascade)	26	3.06e-01	-0.116000	5.37e-01
Cellular hexose transport	17	3.07e-01	-0.143000	5.37e-01
Gamma carboxylation, hypusine formation and arylsulfatase activation	34	3.07e-01	0.101000	5.37e-01
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation	10	3.08e-01	0.186000	5.37e-01
Negative epigenetic regulation of rRNA expression	64	3.09e-01	-0.073500	5.39e-01
Nuclear Receptor transcription pathway	44	3.10e-01	0.088400	5.40e-01
Pregnenolone biosynthesis	11	3.10e-01	0.177000	5.40e-01
Pexophagy	11	3.11e-01	0.176000	5.41e-01
Signaling by NODAL	14	3.12e-01	-0.156000	5.41e-01
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins	75	3.12e-01	-0.067500	5.41e-01
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	32	3.13e-01	0.103000	5.41e-01
FRS-mediated FGFR2 signaling	17	3.15e-01	0.141000	5.44e-01
Heme signaling	45	3.15e-01	0.086500	5.44e-01
SUMOylation of transcription factors	16	3.16e-01	0.145000	5.44e-01
RHO GTPases activate CIT	19	3.16e-01	0.133000	5.44e-01
Gap junction degradation	10	3.17e-01	0.183000	5.44e-01
Adenylate cyclase inhibitory pathway	12	3.18e-01	0.167000	5.44e-01
Gene expression (Transcription)	1378	3.18e-01	0.016100	5.44e-01
Signaling by SCF-KIT	42	3.18e-01	0.089100	5.44e-01
Signaling by ALK	26	3.18e-01	0.113000	5.44e-01
Insulin processing	24	3.19e-01	0.117000	5.44e-01
The activation of arylsulfatases	11	3.20e-01	0.173000	5.44e-01
S33 mutants of beta-catenin aren’t phosphorylated	15	3.21e-01	0.148000	5.44e-01
S37 mutants of beta-catenin aren’t phosphorylated	15	3.21e-01	0.148000	5.44e-01
S45 mutants of beta-catenin aren’t phosphorylated	15	3.21e-01	0.148000	5.44e-01
Signaling by CTNNB1 phospho-site mutants	15	3.21e-01	0.148000	5.44e-01
Signaling by GSK3beta mutants	15	3.21e-01	0.148000	5.44e-01
T41 mutants of beta-catenin aren’t phosphorylated	15	3.21e-01	0.148000	5.44e-01
Stimuli-sensing channels	78	3.21e-01	0.065000	5.44e-01
Sensory processing of sound	59	3.22e-01	0.074600	5.44e-01
AKT phosphorylates targets in the nucleus	10	3.22e-01	0.181000	5.44e-01
PTEN Regulation	140	3.22e-01	0.048500	5.44e-01
CD28 co-stimulation	32	3.24e-01	-0.101000	5.46e-01
HCMV Infection	98	3.24e-01	-0.057700	5.46e-01
Metabolism of amine-derived hormones	11	3.26e-01	-0.171000	5.49e-01
Metabolism of steroids	124	3.27e-01	0.051000	5.50e-01
RNA Polymerase III Chain Elongation	18	3.27e-01	0.133000	5.50e-01
Membrane binding and targetting of GAG proteins	14	3.29e-01	0.151000	5.51e-01
Synthesis And Processing Of GAG, GAGPOL Polyproteins	14	3.29e-01	0.151000	5.51e-01
APC-Cdc20 mediated degradation of Nek2A	26	3.30e-01	-0.110000	5.51e-01
Meiotic synapsis	43	3.30e-01	-0.085800	5.51e-01
Interleukin-12 family signaling	50	3.30e-01	0.079600	5.51e-01
GPCR downstream signalling	430	3.31e-01	0.027400	5.51e-01
GLI3 is processed to GLI3R by the proteasome	57	3.31e-01	0.074500	5.51e-01
Hedgehog ligand biogenesis	62	3.37e-01	0.070500	5.61e-01
Potassium Channels	67	3.39e-01	0.067500	5.64e-01
mRNA Capping	29	3.43e-01	0.102000	5.68e-01
Spry regulation of FGF signaling	16	3.43e-01	0.137000	5.68e-01
Postmitotic nuclear pore complex (NPC) reformation	27	3.43e-01	-0.105000	5.68e-01
Lysine catabolism	11	3.45e-01	-0.165000	5.70e-01
Acyl chain remodelling of PI	12	3.45e-01	0.157000	5.71e-01
SIRT1 negatively regulates rRNA expression	23	3.47e-01	-0.113000	5.72e-01
Acyl chain remodelling of PC	21	3.49e-01	-0.118000	5.75e-01
Packaging Of Telomere Ends	20	3.49e-01	-0.121000	5.75e-01
Formation of the cornified envelope	24	3.52e-01	0.110000	5.79e-01
Costimulation by the CD28 family	68	3.53e-01	-0.065200	5.80e-01
TP53 Regulates Transcription of Cell Death Genes	42	3.54e-01	0.082700	5.81e-01
NCAM signaling for neurite out-growth	50	3.55e-01	0.075700	5.81e-01
Formation of apoptosome	11	3.55e-01	0.161000	5.81e-01
Regulation of the apoptosome activity	11	3.55e-01	0.161000	5.81e-01
Uptake and actions of bacterial toxins	27	3.56e-01	0.103000	5.81e-01
Signaling by Retinoic Acid	39	3.56e-01	0.085400	5.81e-01
NCAM1 interactions	29	3.57e-01	0.098700	5.82e-01
Pentose phosphate pathway	13	3.58e-01	-0.147000	5.82e-01
Degradation of GLI2 by the proteasome	57	3.58e-01	0.070400	5.82e-01
Toll Like Receptor 4 (TLR4) Cascade	127	3.59e-01	0.047100	5.83e-01
NOTCH2 intracellular domain regulates transcription	11	3.61e-01	0.159000	5.86e-01
TRP channels	18	3.62e-01	0.124000	5.86e-01
Transport of vitamins, nucleosides, and related molecules	34	3.62e-01	0.090400	5.86e-01
TP53 Regulates Transcription of Death Receptors and Ligands	12	3.63e-01	0.152000	5.88e-01
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	36	3.65e-01	0.087200	5.90e-01
Interleukin-1 family signaling	128	3.68e-01	0.046100	5.94e-01
Metabolic disorders of biological oxidation enzymes	25	3.70e-01	0.103000	5.97e-01
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	44	3.71e-01	0.078000	5.97e-01
cGMP effects	15	3.73e-01	0.133000	6.00e-01
Regulation of innate immune responses to cytosolic DNA	14	3.74e-01	-0.137000	6.00e-01
p75NTR signals via NF-kB	16	3.75e-01	0.128000	6.00e-01
MET activates RAP1 and RAC1	11	3.75e-01	0.154000	6.00e-01
MyD88:MAL(TIRAP) cascade initiated on plasma membrane	97	3.76e-01	0.052000	6.00e-01
Toll Like Receptor 2 (TLR2) Cascade	97	3.76e-01	0.052000	6.00e-01
Toll Like Receptor TLR1:TLR2 Cascade	97	3.76e-01	0.052000	6.00e-01
Toll Like Receptor TLR6:TLR2 Cascade	97	3.76e-01	0.052000	6.00e-01
FRS-mediated FGFR4 signaling	16	3.77e-01	0.128000	6.00e-01
Triglyceride metabolism	26	3.77e-01	-0.100000	6.00e-01
Interleukin-37 signaling	20	3.77e-01	0.114000	6.00e-01
RNA Polymerase III Transcription Initiation From Type 3 Promoter	28	3.77e-01	0.096400	6.00e-01
Tryptophan catabolism	12	3.80e-01	-0.146000	6.04e-01
ISG15 antiviral mechanism	72	3.81e-01	0.059800	6.04e-01
TCR signaling	116	3.81e-01	-0.047100	6.04e-01
Signal transduction by L1	21	3.82e-01	0.110000	6.05e-01
Endosomal Sorting Complex Required For Transport (ESCRT)	31	3.83e-01	0.090600	6.05e-01
Inactivation, recovery and regulation of the phototransduction cascade	22	3.83e-01	-0.107000	6.05e-01
Hh mutants abrogate ligand secretion	56	3.84e-01	0.067300	6.05e-01
Retinoid metabolism and transport	32	3.88e-01	0.088200	6.11e-01
Signalling to ERKs	33	3.89e-01	0.086600	6.12e-01
RHO GTPases activate PAKs	21	3.91e-01	0.108000	6.14e-01
Toll-like Receptor Cascades	149	3.92e-01	0.040600	6.16e-01
Degradation of DVL	55	3.93e-01	0.066700	6.16e-01
TICAM1,TRAF6-dependent induction of TAK1 complex	11	3.93e-01	0.149000	6.16e-01
DNA Damage Recognition in GG-NER	38	3.94e-01	-0.080000	6.16e-01
VxPx cargo-targeting to cilium	18	3.97e-01	0.115000	6.21e-01
Interleukin receptor SHC signaling	23	3.98e-01	-0.102000	6.21e-01
APC/C:Cdc20 mediated degradation of mitotic proteins	74	3.98e-01	-0.056800	6.21e-01
FGFR2 alternative splicing	24	3.98e-01	0.099600	6.21e-01
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase	20	4.00e-01	-0.109000	6.22e-01
RNA Pol II CTD phosphorylation and interaction with CE	27	4.00e-01	0.093500	6.22e-01
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection	27	4.00e-01	0.093500	6.22e-01
Protein localization	158	4.01e-01	0.038800	6.22e-01
NIK–>noncanonical NF-kB signaling	57	4.01e-01	0.064300	6.22e-01
GAB1 signalosome	16	4.02e-01	0.121000	6.22e-01
Signaling by Erythropoietin	24	4.06e-01	-0.098000	6.27e-01
Metabolism of nucleotides	85	4.06e-01	-0.052100	6.27e-01
Degradation of AXIN	53	4.07e-01	0.065900	6.27e-01
Transcriptional Regulation by MECP2	55	4.07e-01	0.064600	6.27e-01
NoRC negatively regulates rRNA expression	61	4.07e-01	-0.061400	6.27e-01
Interleukin-17 signaling	67	4.09e-01	0.058400	6.29e-01
Deubiquitination	243	4.11e-01	-0.030600	6.32e-01
Detoxification of Reactive Oxygen Species	33	4.13e-01	-0.082400	6.34e-01
mitochondrial fatty acid beta-oxidation of saturated fatty acids	10	4.14e-01	-0.149000	6.35e-01
Activation of HOX genes during differentiation	75	4.15e-01	0.054400	6.35e-01
Activation of anterior HOX genes in hindbrain development during early embryogenesis	75	4.15e-01	0.054400	6.35e-01
Carnitine metabolism	12	4.16e-01	-0.136000	6.35e-01
SARS-CoV-2 Infection	70	4.16e-01	0.056200	6.35e-01
CD28 dependent Vav1 pathway	11	4.16e-01	-0.141000	6.35e-01
Metabolism of vitamins and cofactors	167	4.17e-01	0.036400	6.35e-01
Surfactant metabolism	19	4.18e-01	-0.107000	6.35e-01
Interconversion of nucleotide di- and triphosphates	28	4.18e-01	0.088500	6.35e-01
APC/C:Cdc20 mediated degradation of Cyclin B	24	4.18e-01	-0.095500	6.35e-01
Negative regulators of DDX58/IFIH1 signaling	35	4.18e-01	0.079100	6.35e-01
Cyclin A:Cdk2-associated events at S phase entry	85	4.19e-01	-0.050700	6.36e-01
Cell recruitment (pro-inflammatory response)	24	4.20e-01	-0.095100	6.36e-01
Purinergic signaling in leishmaniasis infection	24	4.20e-01	-0.095100	6.36e-01
Constitutive Signaling by Aberrant PI3K in Cancer	66	4.21e-01	0.057300	6.36e-01
Phospholipase C-mediated cascade; FGFR2	10	4.22e-01	0.147000	6.37e-01
CaMK IV-mediated phosphorylation of CREB	10	4.23e-01	0.146000	6.37e-01
Autophagy	127	4.24e-01	0.041100	6.37e-01
Bile acid and bile salt metabolism	30	4.24e-01	-0.084300	6.37e-01
Acyl chain remodelling of PS	17	4.24e-01	0.112000	6.37e-01
Initiation of Nuclear Envelope (NE) Reformation	19	4.25e-01	-0.106000	6.37e-01
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	74	4.25e-01	0.053700	6.37e-01
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	11	4.29e-01	-0.138000	6.43e-01
CDK-mediated phosphorylation and removal of Cdc6	71	4.32e-01	-0.054000	6.46e-01
Synthesis of substrates in N-glycan biosythesis	59	4.32e-01	0.059200	6.46e-01
PI3K events in ERBB2 signaling	15	4.33e-01	-0.117000	6.46e-01
Ubiquitin-dependent degradation of Cyclin D	50	4.33e-01	0.064100	6.46e-01
Activation of the AP-1 family of transcription factors	10	4.33e-01	0.143000	6.46e-01
ABC-family proteins mediated transport	95	4.35e-01	-0.046300	6.48e-01
Synthesis of IP2, IP, and Ins in the cytosol	12	4.36e-01	0.130000	6.48e-01
Diseases associated with the TLR signaling cascade	28	4.37e-01	-0.084900	6.48e-01
Diseases of Immune System	28	4.37e-01	-0.084900	6.48e-01
Cyclin D associated events in G1	47	4.37e-01	-0.065500	6.48e-01
G1 Phase	47	4.37e-01	-0.065500	6.48e-01
CD209 (DC-SIGN) signaling	20	4.40e-01	0.099800	6.51e-01
FGFR2 ligand binding and activation	11	4.40e-01	0.134000	6.51e-01
Response of Mtb to phagocytosis	23	4.41e-01	0.092800	6.51e-01
Amine ligand-binding receptors	14	4.42e-01	-0.119000	6.52e-01
HIV Life Cycle	146	4.43e-01	-0.036800	6.54e-01
Regulation of RUNX3 expression and activity	55	4.44e-01	0.059700	6.54e-01
DAP12 signaling	28	4.45e-01	-0.083400	6.54e-01
Cleavage of the damaged pyrimidine	29	4.45e-01	-0.081900	6.54e-01
Depyrimidination	29	4.45e-01	-0.081900	6.54e-01
Recognition and association of DNA glycosylase with site containing an affected pyrimidine	29	4.45e-01	-0.081900	6.54e-01
Establishment of Sister Chromatid Cohesion	11	4.46e-01	-0.133000	6.54e-01
Signalling to RAS	20	4.47e-01	0.098100	6.55e-01
Regulated proteolysis of p75NTR	11	4.49e-01	0.132000	6.57e-01
Voltage gated Potassium channels	26	4.55e-01	-0.084700	6.64e-01
Golgi Associated Vesicle Biogenesis	55	4.56e-01	0.058100	6.64e-01
IRF3-mediated induction of type I IFN	12	4.57e-01	-0.124000	6.64e-01
Post-chaperonin tubulin folding pathway	18	4.57e-01	-0.101000	6.64e-01
Termination of O-glycan biosynthesis	15	4.57e-01	-0.111000	6.64e-01
RHOA GTPase cycle	146	4.57e-01	0.035600	6.64e-01
Degradation of GLI1 by the proteasome	57	4.58e-01	0.056900	6.64e-01
Activation of BH3-only proteins	30	4.58e-01	0.078300	6.64e-01
Sealing of the nuclear envelope (NE) by ESCRT-III	25	4.59e-01	-0.085600	6.65e-01
Unfolded Protein Response (UPR)	91	4.60e-01	0.044800	6.65e-01
Chaperonin-mediated protein folding	80	4.61e-01	0.047700	6.65e-01
Regulation of gene expression by Hypoxia-inducible Factor	10	4.61e-01	0.135000	6.65e-01
Protein folding	86	4.61e-01	0.046000	6.65e-01
Glyoxylate metabolism and glycine degradation	25	4.61e-01	-0.085100	6.65e-01
Estrogen-dependent gene expression	102	4.62e-01	0.042200	6.65e-01
Synthesis of PE	12	4.63e-01	-0.122000	6.66e-01
Aberrant regulation of mitotic exit in cancer due to RB1 defects	20	4.63e-01	-0.094800	6.66e-01
SHC-mediated cascade:FGFR1	14	4.64e-01	0.113000	6.66e-01
RNA Polymerase III Transcription Initiation	36	4.64e-01	0.070500	6.66e-01
ER-Phagosome pathway	86	4.66e-01	0.045500	6.68e-01
Glucose metabolism	85	4.67e-01	-0.045700	6.68e-01
Oxidative Stress Induced Senescence	78	4.67e-01	-0.047700	6.68e-01
PI Metabolism	78	4.68e-01	0.047600	6.69e-01
PI-3K cascade:FGFR1	14	4.68e-01	0.112000	6.69e-01
RUNX3 regulates p14-ARF	10	4.70e-01	0.132000	6.70e-01
TNFs bind their physiological receptors	27	4.70e-01	0.080400	6.70e-01
Glycerophospholipid biosynthesis	113	4.71e-01	-0.039300	6.70e-01
KSRP (KHSRP) binds and destabilizes mRNA	17	4.72e-01	-0.101000	6.70e-01
Activation of NF-kappaB in B cells	65	4.72e-01	0.051500	6.70e-01
Cellular Senescence	144	4.72e-01	-0.034700	6.70e-01
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10	13	4.75e-01	-0.115000	6.70e-01
HIV Transcription Initiation	45	4.75e-01	0.061500	6.70e-01
RNA Polymerase II HIV Promoter Escape	45	4.75e-01	0.061500	6.70e-01
RNA Polymerase II Promoter Escape	45	4.75e-01	0.061500	6.70e-01
RNA Polymerase II Transcription Initiation	45	4.75e-01	0.061500	6.70e-01
RNA Polymerase II Transcription Initiation And Promoter Clearance	45	4.75e-01	0.061500	6.70e-01
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening	45	4.75e-01	0.061500	6.70e-01
Regulation of Apoptosis	51	4.76e-01	0.057800	6.70e-01
Vif-mediated degradation of APOBEC3G	52	4.79e-01	0.056700	6.74e-01
Negative regulation of TCF-dependent signaling by WNT ligand antagonists	13	4.80e-01	0.113000	6.74e-01
TICAM1-dependent activation of IRF3/IRF7	12	4.82e-01	0.117000	6.77e-01
HDMs demethylate histones	22	4.82e-01	-0.086500	6.77e-01
Activation of Matrix Metalloproteinases	27	4.83e-01	0.078100	6.77e-01
IRAK1 recruits IKK complex	10	4.84e-01	-0.128000	6.77e-01
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation	10	4.84e-01	-0.128000	6.77e-01
PECAM1 interactions	12	4.85e-01	0.117000	6.77e-01
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	72	4.85e-01	-0.047600	6.77e-01
RHOD GTPase cycle	52	4.87e-01	0.055700	6.79e-01
Base-Excision Repair, AP Site Formation	31	4.89e-01	-0.071800	6.80e-01
VEGFR2 mediated vascular permeability	27	4.89e-01	0.076900	6.80e-01
Endosomal/Vacuolar pathway	12	4.89e-01	0.115000	6.80e-01
Purine salvage	13	4.89e-01	-0.111000	6.80e-01
Disorders of transmembrane transporters	147	4.90e-01	-0.033000	6.80e-01
Early Phase of HIV Life Cycle	14	4.91e-01	-0.106000	6.81e-01
Visual phototransduction	67	4.94e-01	-0.048300	6.85e-01
Synthesis of PA	33	4.96e-01	-0.068400	6.87e-01
RHOBTB3 ATPase cycle	10	4.97e-01	-0.124000	6.88e-01
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1	18	4.98e-01	-0.092200	6.89e-01
Synthesis of glycosylphosphatidylinositol (GPI)	18	4.99e-01	-0.092000	6.89e-01
SUMOylation of chromatin organization proteins	57	5.00e-01	-0.051700	6.89e-01
MicroRNA (miRNA) biogenesis	26	5.00e-01	0.076400	6.89e-01
Telomere C-strand synthesis initiation	13	5.02e-01	-0.108000	6.91e-01
Metabolism of fat-soluble vitamins	36	5.02e-01	0.064600	6.91e-01
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism	12	5.04e-01	-0.112000	6.91e-01
alpha-linolenic acid (ALA) metabolism	12	5.04e-01	-0.112000	6.91e-01
Gene Silencing by RNA	91	5.05e-01	-0.040400	6.93e-01
Host Interactions of HIV factors	128	5.06e-01	-0.034100	6.93e-01
Platelet Aggregation (Plug Formation)	33	5.08e-01	-0.066600	6.95e-01
G alpha (i) signalling events	216	5.10e-01	0.026000	6.97e-01
Plasma lipoprotein clearance	30	5.12e-01	0.069200	6.99e-01
Sensory perception of taste	20	5.14e-01	0.084300	7.02e-01
Caspase activation via Death Receptors in the presence of ligand	16	5.17e-01	0.093600	7.05e-01
IGF1R signaling cascade	43	5.18e-01	0.057000	7.06e-01
RNA Polymerase I Promoter Clearance	65	5.19e-01	-0.046200	7.06e-01
RNA Polymerase I Transcription	65	5.19e-01	-0.046200	7.06e-01
ROS and RNS production in phagocytes	34	5.19e-01	0.063900	7.06e-01
Vpu mediated degradation of CD4	50	5.21e-01	0.052500	7.07e-01
Regulation of TLR by endogenous ligand	15	5.23e-01	0.095300	7.08e-01
Glutathione conjugation	30	5.23e-01	0.067300	7.08e-01
Regulation of activated PAK-2p34 by proteasome mediated degradation	48	5.24e-01	0.053200	7.08e-01
Cobalamin (Cbl, vitamin B12) transport and metabolism	16	5.24e-01	0.092100	7.08e-01
IRS-mediated signalling	39	5.26e-01	0.058700	7.09e-01
Positive epigenetic regulation of rRNA expression	61	5.26e-01	-0.047000	7.09e-01
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint	72	5.26e-01	-0.043200	7.09e-01
Regulation of BACH1 activity	11	5.28e-01	0.110000	7.11e-01
RMTs methylate histone arginines	37	5.28e-01	-0.059900	7.11e-01
SUMOylation of DNA methylation proteins	16	5.29e-01	0.090800	7.12e-01
Degradation of beta-catenin by the destruction complex	83	5.30e-01	0.039900	7.12e-01
Sema3A PAK dependent Axon repulsion	16	5.30e-01	0.090600	7.12e-01
TAK1 activates NFkB by phosphorylation and activation of IKKs complex	28	5.31e-01	-0.068500	7.12e-01
Intra-Golgi traffic	42	5.33e-01	0.055600	7.14e-01
Factors involved in megakaryocyte development and platelet production	115	5.34e-01	-0.033600	7.14e-01
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis	53	5.36e-01	0.049200	7.14e-01
Vesicle-mediated transport	678	5.36e-01	-0.013900	7.14e-01
Signaling by ERBB2 in Cancer	25	5.37e-01	0.071400	7.14e-01
tRNA Aminoacylation	42	5.38e-01	-0.055000	7.14e-01
RNA Polymerase III Transcription Termination	23	5.38e-01	0.074200	7.14e-01
Caspase-mediated cleavage of cytoskeletal proteins	12	5.39e-01	-0.103000	7.14e-01
APC truncation mutants have impaired AXIN binding	14	5.39e-01	0.094800	7.14e-01
AXIN missense mutants destabilize the destruction complex	14	5.39e-01	0.094800	7.14e-01
Signaling by AMER1 mutants	14	5.39e-01	0.094800	7.14e-01
Signaling by APC mutants	14	5.39e-01	0.094800	7.14e-01
Signaling by AXIN mutants	14	5.39e-01	0.094800	7.14e-01
Truncations of AMER1 destabilize the destruction complex	14	5.39e-01	0.094800	7.14e-01
Insulin receptor signalling cascade	44	5.41e-01	0.053300	7.15e-01
Alpha-protein kinase 1 signaling pathway	11	5.43e-01	0.106000	7.17e-01
Advanced glycosylation endproduct receptor signaling	13	5.44e-01	-0.097300	7.18e-01
The role of Nef in HIV-1 replication and disease pathogenesis	27	5.44e-01	-0.067400	7.18e-01
RNA Polymerase III Transcription Initiation From Type 1 Promoter	28	5.45e-01	0.066100	7.18e-01
SARS-CoV Infections	152	5.46e-01	0.028400	7.18e-01
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex	13	5.46e-01	-0.096800	7.18e-01
GRB2 events in ERBB2 signaling	15	5.46e-01	-0.090000	7.18e-01
The phototransduction cascade	23	5.47e-01	-0.072600	7.18e-01
NF-kB is activated and signals survival	13	5.47e-01	0.096400	7.18e-01
Transport of inorganic cations/anions and amino acids/oligopeptides	81	5.47e-01	0.038700	7.18e-01
Transcriptional regulation of pluripotent stem cells	22	5.49e-01	0.073900	7.19e-01
Cyclin E associated events during G1/S transition	83	5.50e-01	-0.038000	7.19e-01
Depolymerisation of the Nuclear Lamina	15	5.51e-01	-0.088900	7.20e-01
Macroautophagy	112	5.52e-01	0.032600	7.21e-01
Gastrin-CREB signalling pathway via PKC and MAPK	16	5.53e-01	0.085600	7.22e-01
Hh mutants are degraded by ERAD	53	5.55e-01	0.046900	7.22e-01
Cellular response to chemical stress	151	5.55e-01	0.027900	7.22e-01
RNA Polymerase III Transcription Initiation From Type 2 Promoter	27	5.56e-01	0.065500	7.24e-01
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	93	5.57e-01	0.035200	7.25e-01
Retrograde neurotrophin signalling	14	5.58e-01	0.090400	7.25e-01
RHOH GTPase cycle	34	5.60e-01	0.057800	7.26e-01
CD28 dependent PI3K/Akt signaling	21	5.61e-01	-0.073300	7.27e-01
AKT phosphorylates targets in the cytosol	14	5.61e-01	0.089600	7.27e-01
Regulation of HMOX1 expression and activity	63	5.64e-01	0.042100	7.29e-01
Signaling by FLT3 ITD and TKD mutants	16	5.64e-01	-0.083300	7.29e-01
Signaling by ERBB2 KD Mutants	24	5.65e-01	0.067900	7.30e-01
Disorders of Developmental Biology	13	5.68e-01	-0.091400	7.32e-01
Disorders of Nervous System Development	13	5.68e-01	-0.091400	7.32e-01
Loss of function of MECP2 in Rett syndrome	13	5.68e-01	-0.091400	7.32e-01
Pervasive developmental disorders	13	5.68e-01	-0.091400	7.32e-01
TNF signaling	44	5.69e-01	0.049700	7.32e-01
Interleukin-12 signaling	42	5.71e-01	0.050600	7.33e-01
RAB GEFs exchange GTP for GDP on RABs	89	5.72e-01	0.034700	7.34e-01
CDT1 association with the CDC6:ORC:origin complex	57	5.72e-01	-0.043200	7.34e-01
Formation of Incision Complex in GG-NER	43	5.73e-01	0.049700	7.35e-01
NOD1/2 Signaling Pathway	32	5.76e-01	-0.057100	7.38e-01
Glycogen breakdown (glycogenolysis)	15	5.78e-01	0.083000	7.40e-01
Negative regulation of NOTCH4 signaling	54	5.79e-01	0.043700	7.40e-01
Late Phase of HIV Life Cycle	133	5.80e-01	-0.027800	7.41e-01
GRB2:SOS provides linkage to MAPK signaling for Integrins	12	5.83e-01	0.091600	7.43e-01
Cdc20:Phospho-APC/C mediated degradation of Cyclin A	71	5.83e-01	-0.037700	7.43e-01
Sensory perception of sweet, bitter, and umami (glutamate) taste	16	5.86e-01	0.078600	7.47e-01
Regulation of TP53 Expression and Degradation	37	5.87e-01	-0.051600	7.47e-01
Acyl chain remodelling of PE	21	5.88e-01	-0.068300	7.48e-01
MHC class II antigen presentation	102	5.90e-01	0.030900	7.50e-01
Integrin signaling	24	5.96e-01	0.062600	7.55e-01
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	29	5.96e-01	0.056900	7.55e-01
Josephin domain DUBs	10	5.97e-01	0.096600	7.56e-01
Regulation of mRNA stability by proteins that bind AU-rich elements	87	5.99e-01	0.032600	7.58e-01
Regulation of KIT signaling	16	6.02e-01	0.075300	7.62e-01
The NLRP3 inflammasome	16	6.04e-01	0.074900	7.64e-01
FOXO-mediated transcription	60	6.05e-01	0.038600	7.65e-01
Transcriptional regulation by RUNX1	185	6.08e-01	-0.021900	7.67e-01
Constitutive Signaling by AKT1 E17K in Cancer	26	6.10e-01	0.057700	7.69e-01
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	14	6.11e-01	0.078600	7.69e-01
Mitochondrial Fatty Acid Beta-Oxidation	35	6.12e-01	0.049500	7.70e-01
RUNX1 regulates transcription of genes involved in differentiation of HSCs	82	6.13e-01	-0.032300	7.70e-01
SLBP independent Processing of Histone Pre-mRNAs	10	6.13e-01	0.092400	7.70e-01
TICAM1, RIP1-mediated IKK complex recruitment	19	6.14e-01	0.066900	7.70e-01
RNA Polymerase III Abortive And Retractive Initiation	41	6.19e-01	0.044900	7.75e-01
RNA Polymerase III Transcription	41	6.19e-01	0.044900	7.75e-01
mRNA decay by 3’ to 5’ exoribonuclease	16	6.19e-01	-0.071700	7.75e-01
Interleukin-1 signaling	99	6.22e-01	0.028700	7.77e-01
Apoptotic execution phase	46	6.22e-01	-0.042100	7.77e-01
MAPK3 (ERK1) activation	10	6.30e-01	0.088100	7.85e-01
Synthesis of bile acids and bile salts via 24-hydroxycholesterol	11	6.30e-01	0.083900	7.85e-01
AUF1 (hnRNP D0) binds and destabilizes mRNA	53	6.30e-01	0.038200	7.85e-01
Glycolysis	68	6.30e-01	-0.033800	7.85e-01
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	22	6.32e-01	0.058900	7.85e-01
Paradoxical activation of RAF signaling by kinase inactive BRAF	40	6.33e-01	0.043700	7.85e-01
Signaling by RAS mutants	40	6.33e-01	0.043700	7.85e-01
Signaling by moderate kinase activity BRAF mutants	40	6.33e-01	0.043700	7.85e-01
Signaling downstream of RAS mutants	40	6.33e-01	0.043700	7.85e-01
Pre-NOTCH Transcription and Translation	48	6.34e-01	-0.039700	7.85e-01
p38MAPK events	13	6.34e-01	0.076200	7.85e-01
Transcriptional Regulation by VENTX	39	6.37e-01	0.043700	7.88e-01
TP53 Regulates Transcription of DNA Repair Genes	61	6.40e-01	-0.034600	7.91e-01
Erythropoietin activates RAS	13	6.42e-01	-0.074500	7.93e-01
ATF6 (ATF6-alpha) activates chaperone genes	10	6.42e-01	-0.084800	7.93e-01
Aflatoxin activation and detoxification	15	6.45e-01	-0.068700	7.95e-01
Elevation of cytosolic Ca2+ levels	13	6.45e-01	0.073800	7.95e-01
Hyaluronan metabolism	17	6.46e-01	-0.064400	7.95e-01
Autodegradation of the E3 ubiquitin ligase COP1	49	6.46e-01	0.037900	7.95e-01
RAB geranylgeranylation	62	6.48e-01	0.033600	7.96e-01
RHO GTPases activate IQGAPs	11	6.49e-01	0.079300	7.96e-01
Synthesis of PC	27	6.50e-01	0.050400	7.98e-01
Folding of actin by CCT/TriC	10	6.53e-01	0.082000	8.01e-01
IRAK2 mediated activation of TAK1 complex	10	6.55e-01	0.081600	8.02e-01
Negative regulation of the PI3K/AKT network	100	6.55e-01	0.025800	8.02e-01
IRS-related events triggered by IGF1R	42	6.58e-01	0.039500	8.03e-01
CASP8 activity is inhibited	11	6.59e-01	-0.076900	8.03e-01
Dimerization of procaspase-8	11	6.59e-01	-0.076900	8.03e-01
Regulation by c-FLIP	11	6.59e-01	-0.076900	8.03e-01
Free fatty acids regulate insulin secretion	10	6.61e-01	0.080100	8.05e-01
SARS-CoV-1 Infection	49	6.62e-01	0.036100	8.06e-01
mRNA Splicing - Minor Pathway	52	6.65e-01	0.034700	8.08e-01
Downregulation of ERBB2:ERBB3 signaling	13	6.65e-01	0.069300	8.08e-01
Nucleotide-like (purinergic) receptors	15	6.67e-01	-0.064200	8.10e-01
Fatty acyl-CoA biosynthesis	33	6.68e-01	-0.043200	8.10e-01
Cross-presentation of soluble exogenous antigens (endosomes)	47	6.68e-01	0.036100	8.10e-01
Effects of PIP2 hydrolysis	24	6.69e-01	0.050500	8.10e-01
HIV Infection	225	6.71e-01	-0.016500	8.12e-01
Translation of Replicase and Assembly of the Replication Transcription Complex	13	6.71e-01	0.068000	8.12e-01
GABA synthesis, release, reuptake and degradation	14	6.72e-01	0.065300	8.12e-01
Glutamate and glutamine metabolism	12	6.75e-01	0.069900	8.14e-01
RIPK1-mediated regulated necrosis	29	6.75e-01	0.045000	8.14e-01
Regulation of necroptotic cell death	29	6.75e-01	0.045000	8.14e-01
ROS sensing by NFE2L2	55	6.78e-01	0.032400	8.16e-01
VLDLR internalisation and degradation	12	6.79e-01	0.069100	8.17e-01
Metabolism of polyamines	57	6.79e-01	0.031600	8.17e-01
Acyl chain remodelling of PG	13	6.81e-01	0.066000	8.17e-01
RNA Polymerase I Transcription Termination	30	6.82e-01	0.043300	8.18e-01
Clathrin-mediated endocytosis	136	6.85e-01	0.020200	8.21e-01
Defective CFTR causes cystic fibrosis	58	6.85e-01	0.030800	8.21e-01
Ovarian tumor domain proteases	38	6.86e-01	0.037900	8.21e-01
Kinesins	39	6.88e-01	-0.037100	8.24e-01
FRS-mediated FGFR1 signaling	16	6.89e-01	0.057700	8.24e-01
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters	20	6.90e-01	-0.051500	8.24e-01
N-Glycan antennae elongation	13	6.92e-01	-0.063500	8.25e-01
Recycling pathway of L1	27	6.94e-01	0.043700	8.27e-01
Metabolism of Angiotensinogen to Angiotensins	16	6.94e-01	0.056800	8.27e-01
Class I peroxisomal membrane protein import	20	6.99e-01	-0.049900	8.32e-01
Regulation of signaling by CBL	18	7.01e-01	-0.052300	8.33e-01
Triglyceride catabolism	17	7.02e-01	-0.053600	8.34e-01
Listeria monocytogenes entry into host cells	20	7.02e-01	0.049400	8.34e-01
TBC/RABGAPs	45	7.03e-01	-0.032900	8.34e-01
Prefoldin mediated transfer of substrate to CCT/TriC	25	7.05e-01	0.043800	8.36e-01
TNFR1-induced NFkappaB signaling pathway	26	7.09e-01	0.042300	8.40e-01
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism	11	7.10e-01	0.064800	8.40e-01
Metabolism of steroid hormones	24	7.10e-01	0.043800	8.40e-01
Transcriptional activation of mitochondrial biogenesis	52	7.12e-01	0.029600	8.42e-01
Infection with Mycobacterium tuberculosis	27	7.13e-01	0.040900	8.42e-01
Signaling by RAF1 mutants	36	7.14e-01	0.035300	8.42e-01
Energy dependent regulation of mTOR by LKB1-AMPK	28	7.15e-01	-0.039900	8.42e-01
Cohesin Loading onto Chromatin	10	7.16e-01	-0.066400	8.43e-01
Presynaptic depolarization and calcium channel opening	10	7.17e-01	0.066200	8.43e-01
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	22	7.17e-01	-0.044600	8.43e-01
trans-Golgi Network Vesicle Budding	71	7.18e-01	0.024700	8.44e-01
Metabolism of water-soluble vitamins and cofactors	113	7.19e-01	0.019600	8.44e-01
Regulation of PTEN gene transcription	60	7.23e-01	0.026400	8.49e-01
PERK regulates gene expression	32	7.25e-01	0.035900	8.50e-01
Metabolism of cofactors	19	7.30e-01	0.045700	8.55e-01
Beta-catenin phosphorylation cascade	17	7.32e-01	0.048000	8.57e-01
Basigin interactions	23	7.33e-01	-0.041100	8.57e-01
Antigen processing-Cross presentation	101	7.34e-01	0.019600	8.57e-01
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	35	7.37e-01	-0.032800	8.60e-01
IRAK4 deficiency (TLR2/4)	15	7.37e-01	-0.050000	8.60e-01
Processing and activation of SUMO	10	7.38e-01	0.061100	8.60e-01
Rap1 signalling	15	7.39e-01	-0.049700	8.60e-01
Nicotinate metabolism	27	7.41e-01	0.036700	8.62e-01
Cellular response to heat stress	96	7.42e-01	0.019400	8.63e-01
Cytosolic tRNA aminoacylation	24	7.42e-01	0.038700	8.63e-01
Regulation of TP53 Degradation	36	7.45e-01	-0.031400	8.64e-01
mRNA decay by 5’ to 3’ exoribonuclease	15	7.49e-01	0.047800	8.68e-01
MAP2K and MAPK activation	35	7.49e-01	-0.031200	8.68e-01
Degradation of cysteine and homocysteine	13	7.49e-01	-0.051200	8.68e-01
RNA Polymerase I Transcription Initiation	47	7.51e-01	-0.026700	8.69e-01
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells	13	7.52e-01	0.050700	8.69e-01
RHO GTPases activate KTN1	11	7.54e-01	0.054500	8.71e-01
Stabilization of p53	54	7.55e-01	0.024500	8.72e-01
STAT3 nuclear events downstream of ALK signaling	10	7.57e-01	-0.056400	8.74e-01
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol	17	7.59e-01	0.043100	8.74e-01
SUMOylation of transcription cofactors	44	7.61e-01	0.026500	8.75e-01
Frs2-mediated activation	12	7.61e-01	-0.050700	8.75e-01
Trafficking and processing of endosomal TLR	13	7.61e-01	-0.048700	8.75e-01
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	19	7.62e-01	0.040100	8.76e-01
ATF6 (ATF6-alpha) activates chaperones	12	7.63e-01	0.050200	8.76e-01
Negative regulation of MET activity	21	7.65e-01	-0.037700	8.78e-01
FLT3 Signaling	38	7.68e-01	-0.027700	8.79e-01
Inflammasomes	21	7.68e-01	0.037200	8.79e-01
Metabolism of folate and pterines	17	7.72e-01	0.040700	8.83e-01
Interleukin-20 family signaling	16	7.82e-01	0.040000	8.94e-01
UCH proteinases	88	7.83e-01	-0.017000	8.94e-01
Nuclear signaling by ERBB4	30	7.86e-01	0.028600	8.94e-01
Growth hormone receptor signaling	20	7.86e-01	0.035000	8.94e-01
Glutathione synthesis and recycling	11	7.87e-01	-0.047100	8.94e-01
Platelet Adhesion to exposed collagen	13	7.87e-01	-0.043300	8.94e-01
G1/S DNA Damage Checkpoints	65	7.87e-01	-0.019400	8.94e-01
HIV elongation arrest and recovery	32	7.89e-01	-0.027300	8.94e-01
Pausing and recovery of HIV elongation	32	7.89e-01	-0.027300	8.94e-01
MET activates RAS signaling	11	7.89e-01	0.046600	8.94e-01
Mitochondrial calcium ion transport	22	7.89e-01	0.032900	8.94e-01
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways	52	7.89e-01	-0.021400	8.94e-01
Cell-extracellular matrix interactions	16	7.90e-01	-0.038400	8.94e-01
NOTCH1 Intracellular Domain Regulates Transcription	47	7.91e-01	0.022400	8.94e-01
Nucleotide catabolism	26	7.91e-01	-0.030100	8.94e-01
Regulation of MECP2 expression and activity	30	7.92e-01	-0.027800	8.95e-01
Peroxisomal protein import	58	7.93e-01	-0.019900	8.96e-01
Diseases associated with N-glycosylation of proteins	17	7.95e-01	0.036500	8.96e-01
Prolonged ERK activation events	14	7.95e-01	0.040100	8.96e-01
RNA Polymerase II Pre-transcription Events	78	7.95e-01	0.017000	8.96e-01
Formation of the Early Elongation Complex	33	7.97e-01	0.025800	8.97e-01
Formation of the HIV-1 Early Elongation Complex	33	7.97e-01	0.025800	8.97e-01
Deadenylation-dependent mRNA decay	53	7.99e-01	-0.020300	8.97e-01
Repression of WNT target genes	14	7.99e-01	0.039400	8.97e-01
ER Quality Control Compartment (ERQC)	21	8.01e-01	0.031800	8.99e-01
RUNX3 regulates NOTCH signaling	14	8.02e-01	0.038700	8.99e-01
G alpha (s) signalling events	90	8.02e-01	0.015300	8.99e-01
Transcription of the HIV genome	67	8.05e-01	0.017500	9.01e-01
Carboxyterminal post-translational modifications of tubulin	29	8.06e-01	0.026400	9.01e-01
G-protein beta:gamma signalling	28	8.06e-01	0.026800	9.01e-01
HuR (ELAVL1) binds and stabilizes mRNA	10	8.11e-01	-0.043600	9.06e-01
Deadenylation of mRNA	22	8.13e-01	-0.029200	9.07e-01
Defective Intrinsic Pathway for Apoptosis	24	8.14e-01	-0.027700	9.08e-01
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA	17	8.15e-01	0.032900	9.08e-01
P2Y receptors	11	8.18e-01	0.040200	9.10e-01
Mitochondrial iron-sulfur cluster biogenesis	13	8.18e-01	0.036800	9.10e-01
Vitamin B5 (pantothenate) metabolism	17	8.23e-01	-0.031300	9.15e-01
Blood group systems biosynthesis	17	8.26e-01	-0.030800	9.18e-01
Xenobiotics	12	8.28e-01	0.036100	9.19e-01
mTORC1-mediated signalling	24	8.30e-01	0.025400	9.19e-01
Formation of tubulin folding intermediates by CCT/TriC	21	8.30e-01	-0.027100	9.19e-01
Ub-specific processing proteases	170	8.30e-01	-0.009530	9.19e-01
Signaling by Activin	14	8.31e-01	0.033000	9.19e-01
Platelet sensitization by LDL	17	8.31e-01	0.029800	9.20e-01
IRE1alpha activates chaperones	50	8.35e-01	-0.017000	9.21e-01
B-WICH complex positively regulates rRNA expression	46	8.35e-01	-0.017800	9.21e-01
Sialic acid metabolism	29	8.35e-01	0.022300	9.21e-01
Infectious disease	806	8.36e-01	-0.004300	9.21e-01
Translation of Structural Proteins	29	8.36e-01	0.022200	9.21e-01
MyD88 deficiency (TLR2/4)	14	8.38e-01	-0.031500	9.22e-01
Formation of RNA Pol II elongation complex	57	8.39e-01	0.015600	9.22e-01
RNA Polymerase II Transcription Elongation	57	8.39e-01	0.015600	9.22e-01
Uptake and function of anthrax toxins	11	8.45e-01	0.033900	9.29e-01
Phase 4 - resting membrane potential	13	8.47e-01	-0.030900	9.30e-01
Calnexin/calreticulin cycle	26	8.48e-01	0.021700	9.30e-01
PI3K Cascade	35	8.49e-01	0.018700	9.30e-01
Purine catabolism	13	8.50e-01	-0.030200	9.31e-01
TRAF3-dependent IRF activation pathway	14	8.54e-01	0.028500	9.33e-01
DAP12 interactions	38	8.54e-01	-0.017200	9.33e-01
Signaling by Leptin	11	8.54e-01	-0.032000	9.33e-01
LDL clearance	18	8.55e-01	-0.024800	9.33e-01
Intrinsic Pathway of Fibrin Clot Formation	15	8.56e-01	-0.027200	9.33e-01
Cytosolic sensors of pathogen-associated DNA	63	8.56e-01	-0.013200	9.33e-01
Metabolism of lipids	643	8.56e-01	0.004190	9.33e-01
Regulation of ornithine decarboxylase (ODC)	49	8.57e-01	0.014900	9.33e-01
DDX58/IFIH1-mediated induction of interferon-alpha/beta	68	8.59e-01	0.012500	9.34e-01
rRNA modification in the nucleus and cytosol	59	8.60e-01	0.013300	9.35e-01
N-glycan antennae elongation in the medial/trans-Golgi	20	8.62e-01	-0.022500	9.36e-01
Amyloid fiber formation	51	8.62e-01	0.014000	9.36e-01
ABC transporter disorders	71	8.63e-01	0.011900	9.36e-01
Lysosphingolipid and LPA receptors	12	8.70e-01	0.027300	9.43e-01
Rab regulation of trafficking	122	8.71e-01	0.008510	9.43e-01
RORA activates gene expression	18	8.74e-01	-0.021700	9.44e-01
SCF-beta-TrCP mediated degradation of Emi1	53	8.74e-01	0.012600	9.44e-01
Downregulation of ERBB2 signaling	28	8.74e-01	0.017300	9.44e-01
Sensory Perception	156	8.75e-01	-0.007300	9.45e-01
SHC1 events in ERBB2 signaling	21	8.77e-01	0.019500	9.46e-01
MAP3K8 (TPL2)-dependent MAPK1/3 activation	16	8.78e-01	0.022200	9.46e-01
Incretin synthesis, secretion, and inactivation	14	8.79e-01	0.023400	9.46e-01
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	14	8.79e-01	0.023400	9.46e-01
Formation of TC-NER Pre-Incision Complex	53	8.80e-01	0.012000	9.46e-01
Oncogene Induced Senescence	33	8.83e-01	-0.014900	9.47e-01
RNA polymerase II transcribes snRNA genes	71	8.83e-01	0.010100	9.47e-01
Pre-NOTCH Expression and Processing	64	8.83e-01	0.010600	9.47e-01
TRAF6 mediated NF-kB activation	25	8.84e-01	-0.016800	9.47e-01
Biotin transport and metabolism	11	8.84e-01	0.025300	9.47e-01
Formation of HIV-1 elongation complex containing HIV-1 Tat	42	8.85e-01	0.012800	9.47e-01
HIV Transcription Elongation	42	8.85e-01	0.012800	9.47e-01
Tat-mediated elongation of the HIV-1 transcript	42	8.85e-01	0.012800	9.47e-01
Regulation of pyruvate dehydrogenase (PDH) complex	15	8.86e-01	0.021400	9.47e-01
Regulation of TP53 Activity through Association with Co-factors	12	8.89e-01	0.023200	9.48e-01
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer’s disease models	21	8.90e-01	-0.017500	9.48e-01
Neurodegenerative Diseases	21	8.90e-01	-0.017500	9.48e-01
TNFR1-induced proapoptotic signaling	13	8.92e-01	0.021800	9.50e-01
Apoptotic cleavage of cellular proteins	36	8.93e-01	-0.012900	9.51e-01
Pausing and recovery of Tat-mediated HIV elongation	30	8.96e-01	-0.013800	9.52e-01
Tat-mediated HIV elongation arrest and recovery	30	8.96e-01	-0.013800	9.52e-01
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	11	8.97e-01	0.022500	9.53e-01
Hyaluronan uptake and degradation	12	8.98e-01	-0.021300	9.53e-01
FLT3 signaling in disease	28	8.99e-01	-0.013900	9.53e-01
Regulation of PTEN mRNA translation	13	8.99e-01	-0.020400	9.53e-01
Regulation of TNFR1 signaling	35	9.00e-01	0.012200	9.53e-01
MTOR signalling	40	9.03e-01	-0.011100	9.55e-01
Synthesis of bile acids and bile salts via 27-hydroxycholesterol	10	9.05e-01	0.021800	9.55e-01
Phospholipid metabolism	190	9.05e-01	-0.005010	9.55e-01
Downstream TCR signaling	95	9.05e-01	-0.007060	9.55e-01
Abortive elongation of HIV-1 transcript in the absence of Tat	23	9.06e-01	0.014200	9.55e-01
Activation of gene expression by SREBF (SREBP)	42	9.06e-01	0.010500	9.55e-01
Activated NTRK2 signals through FRS2 and FRS3	10	9.06e-01	0.021500	9.55e-01
Interleukin-7 signaling	22	9.07e-01	0.014400	9.55e-01
Inositol phosphate metabolism	45	9.09e-01	0.009900	9.56e-01
Sulfur amino acid metabolism	25	9.10e-01	-0.013100	9.56e-01
FGFR1 mutant receptor activation	26	9.10e-01	0.012900	9.56e-01
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	20	9.11e-01	0.014500	9.56e-01
RA biosynthesis pathway	19	9.13e-01	0.014400	9.58e-01
Signaling by cytosolic FGFR1 fusion mutants	18	9.15e-01	-0.014600	9.59e-01
GPCR ligand binding	269	9.16e-01	0.003720	9.60e-01
Regulation of lipid metabolism by PPARalpha	107	9.18e-01	-0.005750	9.61e-01
ABC transporters in lipid homeostasis	14	9.22e-01	0.015200	9.64e-01
NR1H2 and NR1H3-mediated signaling	42	9.23e-01	-0.008600	9.65e-01
Processing of SMDT1	15	9.26e-01	-0.013800	9.67e-01
SUMOylation of immune response proteins	11	9.27e-01	0.016100	9.67e-01
Maturation of nucleoprotein	11	9.27e-01	-0.016000	9.67e-01
APC/C:Cdc20 mediated degradation of Securin	66	9.28e-01	-0.006460	9.67e-01
Pyruvate metabolism and Citric Acid (TCA) cycle	51	9.30e-01	0.007130	9.69e-01
MET receptor recycling	10	9.31e-01	0.015700	9.69e-01
Regulation of TP53 Activity through Methylation	19	9.34e-01	-0.011000	9.72e-01
Regulation of beta-cell development	24	9.36e-01	0.009540	9.72e-01
Common Pathway of Fibrin Clot Formation	13	9.38e-01	-0.012500	9.73e-01
Formation of the beta-catenin:TCF transactivating complex	46	9.39e-01	-0.006540	9.73e-01
RHO GTPases Activate WASPs and WAVEs	36	9.39e-01	-0.007380	9.73e-01
Signaling by high-kinase activity BRAF mutants	31	9.39e-01	-0.007920	9.73e-01
Interleukin-35 Signalling	11	9.41e-01	0.013000	9.74e-01
Autodegradation of Cdh1 by Cdh1:APC/C	64	9.42e-01	0.005290	9.75e-01
MASTL Facilitates Mitotic Progression	10	9.42e-01	-0.013200	9.75e-01
Prolactin receptor signaling	11	9.44e-01	-0.012300	9.75e-01
tRNA modification in the nucleus and cytosol	43	9.45e-01	-0.006040	9.76e-01
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	26	9.46e-01	-0.007710	9.76e-01
Negative regulation of FLT3	15	9.48e-01	0.009810	9.77e-01
Signaling by ERBB2 TMD/JMD mutants	21	9.49e-01	0.008040	9.78e-01
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	13	9.52e-01	0.009610	9.80e-01
Diseases of carbohydrate metabolism	29	9.53e-01	0.006340	9.80e-01
WNT5A-dependent internalization of FZD4	14	9.53e-01	-0.009060	9.80e-01
Senescence-Associated Secretory Phenotype (SASP)	66	9.54e-01	-0.004100	9.80e-01
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux	35	9.56e-01	0.005410	9.82e-01
Cargo recognition for clathrin-mediated endocytosis	98	9.59e-01	-0.003020	9.82e-01
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A	50	9.60e-01	0.004150	9.82e-01
p53-Independent DNA Damage Response	50	9.60e-01	0.004150	9.82e-01
p53-Independent G1/S DNA damage checkpoint	50	9.60e-01	0.004150	9.82e-01
Branched-chain amino acid catabolism	21	9.60e-01	0.006380	9.82e-01
Lysosome Vesicle Biogenesis	34	9.61e-01	0.004870	9.82e-01
Synthesis of PIPs at the Golgi membrane	15	9.61e-01	0.007290	9.82e-01
Association of TriC/CCT with target proteins during biosynthesis	37	9.62e-01	-0.004560	9.82e-01
Regulation of HSF1-mediated heat shock response	78	9.62e-01	0.003120	9.82e-01
Interaction between L1 and Ankyrins	26	9.65e-01	0.004940	9.84e-01
SCF(Skp2)-mediated degradation of p27/p21	60	9.65e-01	0.003250	9.84e-01
Inhibition of DNA recombination at telomere	35	9.66e-01	-0.004120	9.84e-01
Synthesis of bile acids and bile salts	27	9.69e-01	-0.004350	9.86e-01
SHC1 events in ERBB4 signaling	13	9.72e-01	0.005590	9.89e-01
ATF4 activates genes in response to endoplasmic reticulum stress	27	9.73e-01	0.003780	9.89e-01
PPARA activates gene expression	105	9.76e-01	-0.001690	9.91e-01
Glycogen storage diseases	14	9.76e-01	0.004590	9.91e-01
Receptor Mediated Mitophagy	11	9.79e-01	0.004690	9.91e-01
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	11	9.80e-01	-0.004470	9.91e-01
Notch-HLH transcription pathway	28	9.80e-01	-0.002750	9.91e-01
Other interleukin signaling	23	9.80e-01	-0.003030	9.91e-01
Golgi Cisternae Pericentriolar Stack Reorganization	14	9.80e-01	0.003780	9.91e-01
Synthesis of pyrophosphates in the cytosol	10	9.81e-01	-0.004390	9.91e-01
Biological oxidations	157	9.82e-01	0.001050	9.91e-01
Formation of HIV elongation complex in the absence of HIV Tat	44	9.84e-01	0.001780	9.91e-01
RNA Polymerase I Promoter Escape	46	9.84e-01	0.001740	9.91e-01
Signaling by FLT3 fusion proteins	19	9.84e-01	0.002690	9.91e-01
Potential therapeutics for SARS	84	9.86e-01	-0.001080	9.93e-01
XBP1(S) activates chaperone genes	48	9.87e-01	0.001310	9.93e-01
The role of GTSE1 in G2/M progression after G2 checkpoint	58	9.88e-01	0.001170	9.93e-01
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding	28	9.89e-01	-0.001490	9.94e-01
InlB-mediated entry of Listeria monocytogenes into host cell	15	9.91e-01	0.001690	9.95e-01
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA	17	9.93e-01	0.001150	9.97e-01
TRAF6 mediated IRF7 activation	16	9.94e-01	-0.001050	9.97e-01
p53-Dependent G1 DNA Damage Response	63	9.98e-01	0.000155	9.99e-01
p53-Dependent G1/S DNA damage checkpoint	63	9.98e-01	0.000155	9.99e-01
Competing endogenous RNAs (ceRNAs) regulate PTEN translation	11	9.98e-01	0.000338	9.99e-01
Sensory processing of sound by outer hair cells of the cochlea	40	9.99e-01	0.000159	9.99e-01

---

Detailed Gene set reports

Classical antibody-mediated complement activation

Classical antibody-mediated complement activation

	197
set	Classical antibody-mediated complement activation
setSize	73
pANOVA	4.12e-34
s.dist	-0.823
p.adjustANOVA	5.97e-31

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795
IGLV2-18	-10793
IGKV5-2	-10765
IGLV5-45	-10764
IGLV1-40	-10748
IGLV1-44	-10737
IGLV3-25	-10735
IGLV3-27	-10722
IGLC1	-10709
IGLV4-69	-10707
IGLV3-21	-10693
IGLV1-36	-10689
IGLV1-47	-10672
IGLV6-57	-10655
IGKV4-1	-10646
IGKV2-30	-10624
IGHV3-23	-10617
IGHV2-5	-10606
IGKV1-17	-10600
IGKV3-11	-10566
IGHG3	-10545
IGHG1	-10504
IGLV4-60	-10497
IGKV1-5	-10469
IGLV5-37	-10417
IGHV4-34	-10407
IGHV1-46	-10406
IGLV3-19	-10372
IGKV3-15	-10313
IGKV3-20	-10300
IGKV1D-39	-9965
IGKV1-12	-9925
IGHV3-11	-9849
IGHV1-2	-9703
IGHV3-48	-9695
IGHV2-70	-9600
IGKV1-16	-9486
IGKV2D-40	-9270
IGKC	-9161
IGHV4-59	-8996
IGKV1D-16	-8851
IGHV4-39	-8439
IGLC7	-7752
IGHG4	-7204
C1S	-5158
C1R	-4005
IGKV2D-28	-3452
IGHV1-69	-2950
C1QB	-2314
IGKV1-33	-1353
C1QC	-1297
IGKV1-39	-666
C1QA	1634
IGKV3D-20	2798

---

FCGR activation

FCGR activation

	379
set	FCGR activation
setSize	80
pANOVA	2.18e-33
s.dist	-0.777
p.adjustANOVA	1.58e-30

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795
IGLV2-18	-10793
IGKV5-2	-10765
IGLV5-45	-10764
IGLV1-40	-10748
IGLV1-44	-10737
IGLV3-25	-10735
IGLV3-27	-10722
IGLC1	-10709
IGLV4-69	-10707
IGLV3-21	-10693
IGLV1-36	-10689
IGLV1-47	-10672
IGLV6-57	-10655
IGKV4-1	-10646
IGKV2-30	-10624
IGHV3-23	-10617
IGHV2-5	-10606
IGKV1-17	-10600
IGKV3-11	-10566
IGHG3	-10545
IGHG1	-10504
IGLV4-60	-10497
IGKV1-5	-10469
IGLV5-37	-10417
IGHV4-34	-10407
IGHV1-46	-10406
IGLV3-19	-10372
IGKV3-15	-10313
IGKV3-20	-10300
IGKV1D-39	-9965
IGKV1-12	-9925
IGHV3-11	-9849
IGHV1-2	-9703
IGHV3-48	-9695
IGHV2-70	-9600
IGKV1-16	-9486
CD3G	-9464
IGKV2D-40	-9270
IGKC	-9161
IGHV4-59	-8996
IGKV1D-16	-8851
FGR	-8592
IGHV4-39	-8439
CD247	-8130
IGLC7	-7752
IGHG4	-7204
FCGR3A	-7081
SYK	-6752
HCK	-6369
IGKV2D-28	-3452
IGHV1-69	-2950
FCGR1A	-2052
IGKV1-33	-1353
LYN	-973
IGKV1-39	-666
SRC	116
FCGR2A	712
IGKV3D-20	2798
FYN	2820
YES1	7207

---

Scavenging of heme from plasma

Scavenging of heme from plasma

	1120
set	Scavenging of heme from plasma
setSize	74
pANOVA	7.04e-33
s.dist	-0.802
p.adjustANOVA	3.41e-30

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHA2	-10886
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHA2	-10886
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795
IGLV2-18	-10793
IGKV5-2	-10765
IGLV5-45	-10764
IGLV1-40	-10748
IGLV1-44	-10737
IGLV3-25	-10735
IGLV3-27	-10722
IGLC1	-10709
IGLV4-69	-10707
IGLV3-21	-10693
IGLV1-36	-10689
IGLV1-47	-10672
IGLV6-57	-10655
IGKV4-1	-10646
IGKV2-30	-10624
IGHV3-23	-10617
IGHV2-5	-10606
IGKV1-17	-10600
IGKV3-11	-10566
IGLV4-60	-10497
IGKV1-5	-10469
IGLV5-37	-10417
IGHV4-34	-10407
IGHV1-46	-10406
IGLV3-19	-10372
IGKV3-15	-10313
IGKV3-20	-10300
IGKV1D-39	-9965
IGKV1-12	-9925
IGHV3-11	-9849
IGHV1-2	-9703
IGHV3-48	-9695
IGHA1	-9638
IGHV2-70	-9600
IGKV1-16	-9486
IGKV2D-40	-9270
IGKC	-9161
IGHV4-59	-8996
JCHAIN	-8868
IGKV1D-16	-8851
IGHV4-39	-8439
HBA1	-8158
IGLC7	-7752
HP	-6957
CD163	-5793
HBB	-3886
IGKV2D-28	-3452
IGHV1-69	-2950
IGKV1-33	-1353
IGKV1-39	-666
HPX	1589
IGKV3D-20	2798
APOL1	4259
LRP1	4648

---

Creation of C4 and C2 activators

Creation of C4 and C2 activators

	225
set	Creation of C4 and C2 activators
setSize	78
pANOVA	1.85e-32
s.dist	-0.776
p.adjustANOVA	6.69e-30

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795
IGLV2-18	-10793
IGKV5-2	-10765
IGLV5-45	-10764
IGLV1-40	-10748
IGLV1-44	-10737
IGLV3-25	-10735
IGLV3-27	-10722
IGLC1	-10709
IGLV4-69	-10707
IGLV3-21	-10693
IGLV1-36	-10689
IGLV1-47	-10672
IGLV6-57	-10655
IGKV4-1	-10646
IGKV2-30	-10624
IGHV3-23	-10617
IGHV2-5	-10606
IGKV1-17	-10600
IGKV3-11	-10566
IGHG3	-10545
IGHG1	-10504
IGLV4-60	-10497
IGKV1-5	-10469
IGLV5-37	-10417
IGHV4-34	-10407
IGHV1-46	-10406
IGLV3-19	-10372
MASP2	-10367
IGKV3-15	-10313
IGKV3-20	-10300
IGKV1D-39	-9965
IGKV1-12	-9925
IGHV3-11	-9849
IGHV1-2	-9703
IGHV3-48	-9695
IGHV2-70	-9600
IGKV1-16	-9486
IGKV2D-40	-9270
IGKC	-9161
IGHV4-59	-8996
IGKV1D-16	-8851
IGHV4-39	-8439
IGLC7	-7752
FCN1	-7425
IGHG4	-7204
MASP1	-6824
C1S	-5158
C1R	-4005
IGKV2D-28	-3452
IGHV1-69	-2950
C1QB	-2314
IGKV1-33	-1353
C1QC	-1297
IGKV1-39	-666
C1QA	1634
IGKV3D-20	2798
COLEC11	6993
FCN3	8923

---

Initial triggering of complement

Initial triggering of complement

	555
set	Initial triggering of complement
setSize	85
pANOVA	2.36e-32
s.dist	-0.742
p.adjustANOVA	6.86e-30

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
C3	-10942
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
C3	-10942
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795
IGLV2-18	-10793
IGKV5-2	-10765
IGLV5-45	-10764
IGLV1-40	-10748
IGLV1-44	-10737
IGLV3-25	-10735
IGLV3-27	-10722
IGLC1	-10709
IGLV4-69	-10707
IGLV3-21	-10693
IGLV1-36	-10689
IGLV1-47	-10672
IGLV6-57	-10655
IGKV4-1	-10646
IGKV2-30	-10624
IGHV3-23	-10617
IGHV2-5	-10606
IGKV1-17	-10600
IGKV3-11	-10566
IGHG3	-10545
IGHG1	-10504
IGLV4-60	-10497
IGKV1-5	-10469
IGLV5-37	-10417
IGHV4-34	-10407
IGHV1-46	-10406
IGLV3-19	-10372
MASP2	-10367
IGKV3-15	-10313
IGKV3-20	-10300
IGKV1D-39	-9965
IGKV1-12	-9925
IGHV3-11	-9849
IGHV1-2	-9703
IGHV3-48	-9695
IGHV2-70	-9600
IGKV1-16	-9486
IGKV2D-40	-9270
GZMM	-9243
IGKC	-9161
IGHV4-59	-8996
IGKV1D-16	-8851
IGHV4-39	-8439
IGLC7	-7752
FCN1	-7425
IGHG4	-7204
CFD	-7163
MASP1	-6824
C1S	-5158
C1R	-4005
IGKV2D-28	-3452
C4A	-3187
IGHV1-69	-2950
C1QB	-2314
CFB	-2251
IGKV1-33	-1353
C1QC	-1297
IGKV1-39	-666
C4B	-625
C2	1613
C1QA	1634
IGKV3D-20	2798
COLEC11	6993
FCN3	8923

---

Role of LAT2/NTAL/LAB on calcium mobilization

Role of LAT2/NTAL/LAB on calcium mobilization

	1077
set	Role of LAT2/NTAL/LAB on calcium mobilization
setSize	78
pANOVA	1.71e-28
s.dist	-0.724
p.adjustANOVA	4.14e-26

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795
IGLV2-18	-10793

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795
IGLV2-18	-10793
IGKV5-2	-10765
IGLV5-45	-10764
IGLV1-40	-10748
IGLV1-44	-10737
IGLV3-25	-10735
IGLV3-27	-10722
IGLC1	-10709
IGLV4-69	-10707
IGLV3-21	-10693
IGLV1-36	-10689
IGLV1-47	-10672
IGLV6-57	-10655
IGKV4-1	-10646
IGKV2-30	-10624
IGHV3-23	-10617
IGHV2-5	-10606
IGKV1-17	-10600
IGKV3-11	-10566
IGLV4-60	-10497
IGKV1-5	-10469
IGLV5-37	-10417
IGHV4-34	-10407
IGHV1-46	-10406
IGLV3-19	-10372
IGKV3-15	-10313
IGKV3-20	-10300
IGKV1D-39	-9965
IGKV1-12	-9925
IGHV3-11	-9849
IGHV1-2	-9703
IGHV3-48	-9695
IGHV2-70	-9600
IGKV1-16	-9486
IGKV2D-40	-9270
IGKC	-9161
IGHV4-59	-8996
IGKV1D-16	-8851
IGHE	-8557
IGHV4-39	-8439
IGLC7	-7752
SYK	-6752
GRB2	-6402
LAT2	-5231
PIK3R2	-4348
IGKV2D-28	-3452
GAB2	-3076
IGHV1-69	-2950
IGKV1-33	-1353
SOS1	-1232
LYN	-973
IGKV1-39	-666
PDPK1	-364
PIK3CB	1574
PIK3R1	1940
IGKV3D-20	2798
FYN	2820
PIK3CA	4947
SHC1	7085

---

CD22 mediated BCR regulation

CD22 mediated BCR regulation

	125
set	CD22 mediated BCR regulation
setSize	61
pANOVA	9.9e-27
s.dist	-0.791
p.adjustANOVA	2.05e-24

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLC2	-10988
IGHD	-10987
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGHV3-30	-10939
IGLV2-8	-10924
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGKV5-2	-10765
IGLV1-40	-10748
IGLV1-44	-10737
IGLV3-25	-10735

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLC2	-10988
IGHD	-10987
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGHV3-30	-10939
IGLV2-8	-10924
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGKV5-2	-10765
IGLV1-40	-10748
IGLV1-44	-10737
IGLV3-25	-10735
IGLV3-27	-10722
IGLC1	-10709
IGLV3-21	-10693
IGLV1-47	-10672
IGLV6-57	-10655
IGKV4-1	-10646
IGKV2-30	-10624
IGHV3-23	-10617
IGHV2-5	-10606
IGKV1-17	-10600
IGKV3-11	-10566
IGKV1-5	-10469
IGHV4-34	-10407
IGHV1-46	-10406
IGLV3-19	-10372
IGKV3-15	-10313
IGKV3-20	-10300
IGKV1D-39	-9965
IGKV1-12	-9925
IGHV3-11	-9849
IGHV1-2	-9703
IGHV3-48	-9695
IGHV2-70	-9600
IGKV1-16	-9486
IGKV2D-40	-9270
PTPN6	-9253
IGKC	-9161
IGHM	-9131
IGHV4-59	-8996
IGKV1D-16	-8851
IGHV4-39	-8439
IGLC7	-7752
CD79A	-3963
IGKV2D-28	-3452
IGHV1-69	-2950
IGKV1-33	-1353
LYN	-973
IGKV1-39	-666
CD22	2075
IGKV3D-20	2798
CD79B	3660

---

Role of phospholipids in phagocytosis

Role of phospholipids in phagocytosis

	1078
set	Role of phospholipids in phagocytosis
setSize	93
pANOVA	1.46e-26
s.dist	-0.639
p.adjustANOVA	2.64e-24

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795
IGLV2-18	-10793
IGKV5-2	-10765
IGLV5-45	-10764
IGLV1-40	-10748
IGLV1-44	-10737
IGLV3-25	-10735
IGLV3-27	-10722
IGLC1	-10709
IGLV4-69	-10707
IGLV3-21	-10693
IGLV1-36	-10689
IGLV1-47	-10672
IGLV6-57	-10655
IGKV4-1	-10646
IGKV2-30	-10624
IGHV3-23	-10617
IGHV2-5	-10606
IGKV1-17	-10600
IGKV3-11	-10566
IGHG3	-10545
IGHG1	-10504
IGLV4-60	-10497
IGKV1-5	-10469
IGLV5-37	-10417
IGHV4-34	-10407
IGHV1-46	-10406
IGLV3-19	-10372
IGKV3-15	-10313
IGKV3-20	-10300
IGKV1D-39	-9965
IGKV1-12	-9925
IGHV3-11	-9849
IGHV1-2	-9703
IGHV3-48	-9695
IGHV2-70	-9600
IGKV1-16	-9486
CD3G	-9464
IGKV2D-40	-9270
IGKC	-9161
IGHV4-59	-8996
IGKV1D-16	-8851
PRKCD	-8561
PLD4	-8487
IGHV4-39	-8439
PLA2G6	-8156
CD247	-8130
IGLC7	-7752
IGHG4	-7204
FCGR3A	-7081
SYK	-6752
PLCG2	-6329
PIK3R2	-4348
PLPP4	-3656
IGKV2D-28	-3452
IGHV1-69	-2950
FCGR1A	-2052
IGKV1-33	-1353
IGKV1-39	-666
PLD2	-216
PLPP5	179
FCGR2A	712
PIK3CB	1574
PIK3R1	1940
PLCG1	2063
IGKV3D-20	2798
PLD1	3384
AHCYL1	4052
PLD3	4574
PIK3CA	4947
ITPR1	6224
ITPR3	6415
ITPR2	7099
PRKCE	7875

---

Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

	541
set	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
setSize	178
pANOVA	6.43e-25
s.dist	-0.448
p.adjustANOVA	1.04e-22

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
C3	-10942
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
FCGR2B	-10827
IGKV2-28	-10803

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
C3	-10942
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
FCGR2B	-10827
IGKV2-28	-10803
SIGLEC8	-10797
IGLV10-54	-10795
IGLV2-18	-10793
IGKV5-2	-10765
IGLV5-45	-10764
IGLV1-40	-10748
IGLV1-44	-10737
IGLV3-25	-10735
IGLV3-27	-10722
IGLC1	-10709
IGLV4-69	-10707
IGLV3-21	-10693
IGLV1-36	-10689
IGLV1-47	-10672
LAIR1	-10671
IGLV6-57	-10655
IGKV4-1	-10646
IGKV2-30	-10624
IGHV3-23	-10617
CD1D	-10610
IGHV2-5	-10606
IGKV1-17	-10600
CLEC4G	-10598
TREML1	-10572
IGKV3-11	-10566
IGLV4-60	-10497
IGKV1-5	-10469
IGLV5-37	-10417
IGHV4-34	-10407
IGHV1-46	-10406
IGLV3-19	-10372
SLAMF6	-10341
IGKV3-15	-10313
IGKV3-20	-10300
KLRF1	-10248
ICAM5	-10165
LILRB2	-10136
LILRB1	-10054
CD3E	-9976
LILRB3	-9975
IGKV1D-39	-9965
IGKV1-12	-9925
MADCAM1	-9874
IGHV3-11	-9849
KLRC1	-9769
IGHV1-2	-9703
IGHV3-48	-9695
ITGAL	-9631
IGHV2-70	-9600
IGKV1-16	-9486
CD3G	-9464
CD19	-9309
IGKV2D-40	-9270
IGKC	-9161
ITGB7	-9121
IGHV4-59	-8996
HCST	-8984
SIGLEC5	-8904
CD40LG	-8892
IGKV1D-16	-8851
KLRG1	-8763
LILRA6	-8757
MICB	-8722
NCR1	-8706
SIGLEC10	-8683
OSCAR	-8642
ITGB2	-8620
KLRD1	-8505
IGHV4-39	-8439
CRTAM	-8226
ICAM3	-8190
KLRK1	-8142
CD247	-8130
LILRB5	-8012
IGLC7	-7752
LILRA2	-7749
TREML2	-7700
SIGLEC9	-7640
ICAM4	-7558
SLAMF7	-7441
HLA-F	-7096
FCGR3A	-7081
LILRA1	-6961
CD33	-6779
LAIR2	-6669
CD300LF	-6528
CLEC2D	-6324
PILRB	-6277
TRAC	-6190
CD3D	-5775
PILRA	-5663
LILRB4	-5587
CDH1	-5398
CD96	-5298
TRBC1	-5285
SELL	-5160
LILRA5	-5142
SIGLEC12	-4961
HLA-A	-4124
SIGLEC6	-4111
CD226	-3941
CXADR	-3859
SH2D1B	-3570
CD300LG	-3535
JAML	-3480
IGKV2D-28	-3452
IGHV1-69	-2950
ITGA4	-2658
LILRA4	-2387
SIGLEC7	-2136
TREM2	-2101
FCGR1A	-2052
CD8B	-1429
IGKV1-33	-1353
HLA-E	-1329
TYROBP	-1313
IGKV1-39	-666
VCAM1	-613
HLA-H	-298
CD8A	-208
CD300A	193
KLRB1	1031
SIGLEC11	1280
CD40	1660
B2M	1973
CD22	2075
ICAM2	2152
ULBP3	2174
CD1C	2249
IGKV3D-20	2798
CD300LB	3532
SH2D1A	3903
PIANP	4411
CD160	4689
NPDC1	4711
PVR	4792
TREM1	4953
CD200R1	5120
MICA	5216
COLEC12	5217
CD34	5344
CD81	5586
SIGLEC1	5624
CLEC2B	6004
NCR3	6060
ITGB1	6439
NECTIN2	6512
CD300C	6753
NCR3LG1	6890
HLA-B	7436
CD1B	7800
ICAM1	8067
CD300E	8112
IFITM1	8485
CD99	8627
CD200	8807
HLA-C	8936
HLA-G	9060

---

FCERI mediated MAPK activation

FCERI mediated MAPK activation

	377
set	FCERI mediated MAPK activation
setSize	94
pANOVA	8.62e-24
s.dist	-0.6
p.adjustANOVA	1.25e-21

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795
IGLV2-18	-10793

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795
IGLV2-18	-10793
IGKV5-2	-10765
IGLV5-45	-10764
IGLV1-40	-10748
IGLV1-44	-10737
IGLV3-25	-10735
IGLV3-27	-10722
IGLC1	-10709
IGLV4-69	-10707
IGLV3-21	-10693
IGLV1-36	-10689
IGLV1-47	-10672
IGLV6-57	-10655
IGKV4-1	-10646
IGKV2-30	-10624
IGHV3-23	-10617
IGHV2-5	-10606
IGKV1-17	-10600
IGKV3-11	-10566
IGLV4-60	-10497
IGKV1-5	-10469
IGLV5-37	-10417
IGHV4-34	-10407
IGHV1-46	-10406
IGLV3-19	-10372
IGKV3-15	-10313
IGKV3-20	-10300
IGKV1D-39	-9965
IGKV1-12	-9925
IGHV3-11	-9849
LAT	-9770
IGHV1-2	-9703
IGHV3-48	-9695
IGHV2-70	-9600
IGKV1-16	-9486
IGKV2D-40	-9270
GRAP2	-9252
IGKC	-9161
IGHV4-59	-8996
IGKV1D-16	-8851
VAV1	-8673
IGHE	-8557
IGHV4-39	-8439
LCP2	-7806
IGLC7	-7752
SYK	-6752
GRB2	-6402
PLCG2	-6329
MAPK1	-5806
MAP2K7	-5503
PAK1	-5016
MAPK10	-3533
IGKV2D-28	-3452
IGHV1-69	-2950
MAPK9	-2843
IGKV1-33	-1353
SOS1	-1232
LYN	-973
IGKV1-39	-666
MAPK3	-640
VAV3	765
RAC1	1751
PLCG1	2063
PAK2	2496
IGKV3D-20	2798
VAV2	2828
MAP3K1	3041
MAPK8	3067
MAP2K4	3457
KRAS	3793
NRAS	5076
HRAS	5288
SHC1	7085
FOS	8501
JUN	8707

---

Regulation of Complement cascade

Regulation of Complement cascade

	1008
set	Regulation of Complement cascade
setSize	102
pANOVA	2.42e-23
s.dist	-0.57
p.adjustANOVA	3.19e-21

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV8-61	-11000
C6	-10992
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
C7	-10946
C3	-10942
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV8-61	-11000
C6	-10992
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
C7	-10946
C3	-10942
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795
IGLV2-18	-10793
IGKV5-2	-10765
IGLV5-45	-10764
IGLV1-40	-10748
IGLV1-44	-10737
IGLV3-25	-10735
IGLV3-27	-10722
IGLC1	-10709
IGLV4-69	-10707
IGLV3-21	-10693
IGLV1-36	-10689
IGLV1-47	-10672
IGLV6-57	-10655
IGKV4-1	-10646
IGKV2-30	-10624
IGHV3-23	-10617
IGHV2-5	-10606
IGKV1-17	-10600
IGKV3-11	-10566
IGHG3	-10545
IGHG1	-10504
IGLV4-60	-10497
IGKV1-5	-10469
IGLV5-37	-10417
IGHV4-34	-10407
IGHV1-46	-10406
IGLV3-19	-10372
IGKV3-15	-10313
IGKV3-20	-10300
IGKV1D-39	-9965
IGKV1-12	-9925
IGHV3-11	-9849
IGHV1-2	-9703
IGHV3-48	-9695
IGHV2-70	-9600
IGKV1-16	-9486
C3AR1	-9327
CD19	-9309
IGKV2D-40	-9270
IGKC	-9161
IGHV4-59	-8996
ELANE	-8987
IGKV1D-16	-8851
IGHV4-39	-8439
IGLC7	-7752
IGHG4	-7204
C5	-6624
C8G	-6511
C1S	-5158
C1R	-4005
IGKV2D-28	-3452
C4A	-3187
IGHV1-69	-2950
C1QB	-2314
CFB	-2251
CR1	-2054
IGKV1-33	-1353
C1QC	-1297
IGKV1-39	-666
C4B	-625
CFH	-133
CD46	484
CR2	1181
C2	1613
C1QA	1634
CFI	1754
C5AR1	2424
PROS1	2480
IGKV3D-20	2798
C5AR2	2938
CFHR3	4070
SERPING1	4428
CD81	5586
CD59	6807
CPN2	7651
CLU	8125
C4BPB	8661
CD55	9004
C4BPA	9152

---

Complement cascade

Complement cascade

	209
set	Complement cascade
setSize	109
pANOVA	2.76e-23
s.dist	-0.551
p.adjustANOVA	3.33e-21

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV8-61	-11000
C6	-10992
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
C7	-10946
C3	-10942
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV8-61	-11000
C6	-10992
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
C7	-10946
C3	-10942
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795
IGLV2-18	-10793
IGKV5-2	-10765
IGLV5-45	-10764
IGLV1-40	-10748
IGLV1-44	-10737
IGLV3-25	-10735
IGLV3-27	-10722
IGLC1	-10709
IGLV4-69	-10707
IGLV3-21	-10693
IGLV1-36	-10689
IGLV1-47	-10672
IGLV6-57	-10655
IGKV4-1	-10646
IGKV2-30	-10624
IGHV3-23	-10617
IGHV2-5	-10606
IGKV1-17	-10600
IGKV3-11	-10566
IGHG3	-10545
IGHG1	-10504
IGLV4-60	-10497
IGKV1-5	-10469
IGLV5-37	-10417
IGHV4-34	-10407
IGHV1-46	-10406
IGLV3-19	-10372
MASP2	-10367
IGKV3-15	-10313
IGKV3-20	-10300
IGKV1D-39	-9965
IGKV1-12	-9925
IGHV3-11	-9849
IGHV1-2	-9703
IGHV3-48	-9695
IGHV2-70	-9600
IGKV1-16	-9486
C3AR1	-9327
CD19	-9309
IGKV2D-40	-9270
GZMM	-9243
IGKC	-9161
IGHV4-59	-8996
ELANE	-8987
IGKV1D-16	-8851
IGHV4-39	-8439
IGLC7	-7752
FCN1	-7425
IGHG4	-7204
CFD	-7163
MASP1	-6824
C5	-6624
C8G	-6511
C1S	-5158
C1R	-4005
IGKV2D-28	-3452
C4A	-3187
IGHV1-69	-2950
C1QB	-2314
CFB	-2251
CR1	-2054
IGKV1-33	-1353
C1QC	-1297
IGKV1-39	-666
C4B	-625
CFH	-133
CD46	484
CR2	1181
C2	1613
C1QA	1634
CFI	1754
C5AR1	2424
PROS1	2480
IGKV3D-20	2798
C5AR2	2938
CFHR3	4070
SERPING1	4428
CD81	5586
CD59	6807
COLEC11	6993
CPN2	7651
CLU	8125
C4BPB	8661
FCN3	8923
CD55	9004
C4BPA	9152

---

FCERI mediated Ca+2 mobilization

FCERI mediated Ca+2 mobilization

	376
set	FCERI mediated Ca+2 mobilization
setSize	93
pANOVA	1.2e-22
s.dist	-0.587
p.adjustANOVA	1.34e-20

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795
IGLV2-18	-10793

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795
IGLV2-18	-10793
IGKV5-2	-10765
IGLV5-45	-10764
IGLV1-40	-10748
IGLV1-44	-10737
IGLV3-25	-10735
IGLV3-27	-10722
IGLC1	-10709
IGLV4-69	-10707
IGLV3-21	-10693
IGLV1-36	-10689
IGLV1-47	-10672
IGLV6-57	-10655
IGKV4-1	-10646
IGKV2-30	-10624
IGHV3-23	-10617
IGHV2-5	-10606
IGKV1-17	-10600
IGKV3-11	-10566
IGLV4-60	-10497
IGKV1-5	-10469
IGLV5-37	-10417
IGHV4-34	-10407
IGHV1-46	-10406
IGLV3-19	-10372
IGKV3-15	-10313
IGKV3-20	-10300
IGKV1D-39	-9965
IGKV1-12	-9925
IGHV3-11	-9849
LAT	-9770
IGHV1-2	-9703
IGHV3-48	-9695
IGHV2-70	-9600
IGKV1-16	-9486
IGKV2D-40	-9270
GRAP2	-9252
IGKC	-9161
IGHV4-59	-8996
IGKV1D-16	-8851
VAV1	-8673
IGHE	-8557
IGHV4-39	-8439
TEC	-7871
LCP2	-7806
BTK	-7776
IGLC7	-7752
SYK	-6752
GRB2	-6402
PLCG2	-6329
IGKV2D-28	-3452
IGHV1-69	-2950
TXK	-2779
IGKV1-33	-1353
SOS1	-1232
LYN	-973
IGKV1-39	-666
CALM1	172
VAV3	765
PPP3CB	1050
PPP3R1	1893
PLCG1	2063
IGKV3D-20	2798
VAV2	2828
ITK	3255
AHCYL1	4052
NFATC3	4398
ITPR1	6224
ITPR3	6415
SHC1	7085
ITPR2	7099
NFATC1	7280
PPP3CA	8367
NFATC2	8666

---

Binding and Uptake of Ligands by Scavenger Receptors

Binding and Uptake of Ligands by Scavenger Receptors

	112
set	Binding and Uptake of Ligands by Scavenger Receptors
setSize	102
pANOVA	2.12e-22
s.dist	-0.557
p.adjustANOVA	2.19e-20

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
APOB	-10965
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
STAB2	-10916
IGHV3-33	-10915
SCARA5	-10887
IGHA2	-10886
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
APOB	-10965
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
STAB2	-10916
IGHV3-33	-10915
SCARA5	-10887
IGHA2	-10886
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795
IGLV2-18	-10793
IGKV5-2	-10765
IGLV5-45	-10764
IGLV1-40	-10748
IGLV1-44	-10737
IGLV3-25	-10735
IGLV3-27	-10722
IGLC1	-10709
IGLV4-69	-10707
IGLV3-21	-10693
IGLV1-36	-10689
IGLV1-47	-10672
IGLV6-57	-10655
IGKV4-1	-10646
MARCO	-10642
IGKV2-30	-10624
IGHV3-23	-10617
IGHV2-5	-10606
IGKV1-17	-10600
IGKV3-11	-10566
IGLV4-60	-10497
IGKV1-5	-10469
IGLV5-37	-10417
IGHV4-34	-10407
IGHV1-46	-10406
IGLV3-19	-10372
IGKV3-15	-10313
IGKV3-20	-10300
IGKV1D-39	-9965
IGKV1-12	-9925
IGHV3-11	-9849
IGHV1-2	-9703
IGHV3-48	-9695
IGHA1	-9638
IGHV2-70	-9600
IGKV1-16	-9486
IGKV2D-40	-9270
IGKC	-9161
IGHV4-59	-8996
JCHAIN	-8868
IGKV1D-16	-8851
IGHV4-39	-8439
HBA1	-8158
IGLC7	-7752
CD36	-7512
HYOU1	-6997
HP	-6957
MASP1	-6824
SAA1	-6143
CD163	-5793
CALR	-4286
HBB	-3886
IGKV2D-28	-3452
IGHV1-69	-2950
HSP90B1	-2892
SCARB1	-2745
IGKV1-33	-1353
IGKV1-39	-666
MSR1	-554
SSC5D	-416
SCARF1	860
HPX	1589
STAB1	2215
FTL	2251
IGKV3D-20	2798
HSP90AA1	2976
FTH1	3388
COL4A2	4008
APOL1	4259
LRP1	4648
COLEC12	5217
COL3A1	5610
COLEC11	6993
COL4A1	7213
HSPH1	7476
APOE	8221
COL1A1	8357
COL1A2	8720
SPARC	8869

---

Antigen activates B Cell Receptor (BCR) leading to generation of second messengers

Antigen activates B Cell Receptor (BCR) leading to generation of second messengers

	76
set	Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
setSize	86
pANOVA	5.66e-21
s.dist	-0.586
p.adjustANOVA	4.81e-19

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLC2	-10988
IGHD	-10987
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGHV3-30	-10939
IGLV2-8	-10924
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGKV5-2	-10765
IGLV1-40	-10748
IGLV1-44	-10737
IGLV3-25	-10735

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLC2	-10988
IGHD	-10987
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGHV3-30	-10939
IGLV2-8	-10924
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGKV5-2	-10765
IGLV1-40	-10748
IGLV1-44	-10737
IGLV3-25	-10735
IGLV3-27	-10722
IGLC1	-10709
IGLV3-21	-10693
IGLV1-47	-10672
IGLV6-57	-10655
IGKV4-1	-10646
IGKV2-30	-10624
IGHV3-23	-10617
IGHV2-5	-10606
IGKV1-17	-10600
IGKV3-11	-10566
IGKV1-5	-10469
IGHV4-34	-10407
IGHV1-46	-10406
IGLV3-19	-10372
IGKV3-15	-10313
IGKV3-20	-10300
IGKV1D-39	-9965
IGKV1-12	-9925
IGHV3-11	-9849
IGHV1-2	-9703
IGHV3-48	-9695
IGHV2-70	-9600
IGKV1-16	-9486
CD19	-9309
IGKV2D-40	-9270
PTPN6	-9253
IGKC	-9161
IGHM	-9131
IGHV4-59	-8996
IGKV1D-16	-8851
VAV1	-8673
IGHV4-39	-8439
BTK	-7776
IGLC7	-7752
BLNK	-7235
PIK3CD	-7175
SH3KBP1	-6879
SYK	-6752
GRB2	-6402
PLCG2	-6329
STIM1	-4928
BLK	-4220
CD79A	-3963
IGKV2D-28	-3452
IGHV1-69	-2950
DAPP1	-2231
PIK3AP1	-1747
IGKV1-33	-1353
SOS1	-1232
LYN	-973
ORAI2	-800
IGKV1-39	-666
CALM1	172
PIK3R1	1940
CD22	2075
ORAI1	2584
NCK1	2702
IGKV3D-20	2798
FYN	2820
CD79B	3660
AHCYL1	4052
TRPC1	4785
ITPR1	6224
ITPR3	6415
ITPR2	7099

---

FCGR3A-mediated phagocytosis

FCGR3A-mediated phagocytosis

	381
set	FCGR3A-mediated phagocytosis
setSize	127
pANOVA	5.96e-21
s.dist	-0.482
p.adjustANOVA	4.81e-19

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795
IGLV2-18	-10793
IGKV5-2	-10765
IGLV5-45	-10764
IGLV1-40	-10748
IGLV1-44	-10737
IGLV3-25	-10735
IGLV3-27	-10722
IGLC1	-10709
IGLV4-69	-10707
IGLV3-21	-10693
IGLV1-36	-10689
IGLV1-47	-10672
IGLV6-57	-10655
IGKV4-1	-10646
IGKV2-30	-10624
IGHV3-23	-10617
IGHV2-5	-10606
IGKV1-17	-10600
IGKV3-11	-10566
IGHG3	-10545
IGHG1	-10504
IGLV4-60	-10497
IGKV1-5	-10469
IGLV5-37	-10417
IGHV4-34	-10407
IGHV1-46	-10406
IGLV3-19	-10372
IGKV3-15	-10313
IGKV3-20	-10300
WIPF3	-10297
IGKV1D-39	-9965
IGKV1-12	-9925
IGHV3-11	-9849
IGHV1-2	-9703
IGHV3-48	-9695
IGHV2-70	-9600
IGKV1-16	-9486
CD3G	-9464
IGKV2D-40	-9270
IGKC	-9161
IGHV4-59	-8996
WAS	-8884
IGKV1D-16	-8851
VAV1	-8673
FGR	-8592
IGHV4-39	-8439
CD247	-8130
BTK	-7776
IGLC7	-7752
IGHG4	-7204
FCGR3A	-7081
WASF3	-6883
SYK	-6752
MYH9	-6652
ACTB	-6627
NCKAP1L	-6446
ARPC1B	-6441
GRB2	-6402
HCK	-6369
MAPK1	-5806
ELMO2	-4908
ARPC4	-4772
MYO9B	-4302
NCKIPSD	-4119
WASF2	-4010
IGKV2D-28	-3452
WASF1	-3160
WIPF2	-3140
ARPC1A	-3033
IGHV1-69	-2950
ARPC2	-1824
ABL1	-1394
IGKV1-33	-1353
ACTR3	-1117
LYN	-973
IGKV1-39	-666
MAPK3	-640
ARPC3	-538
MYH2	-289
SRC	116
BRK1	703
VAV3	765
ELMO1	951
ARPC5	990
CDC42	1019
WIPF1	1228
MYO1C	1470
ABI1	1553
CYFIP2	1697
RAC1	1751
MYO5A	2084
ACTR2	2139
NCK1	2702
IGKV3D-20	2798
FYN	2820
VAV2	2828
CRK	3232
ACTG1	3525
WASL	6292
BAIAP2	6532
NCKAP1	6584
PTK2	6843
CYFIP1	6961
DOCK1	7071
YES1	7207
ABI2	7835
MYO10	9031

---

Leishmania phagocytosis

Leishmania phagocytosis

	625
set	Leishmania phagocytosis
setSize	127
pANOVA	5.96e-21
s.dist	-0.482
p.adjustANOVA	4.81e-19

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795
IGLV2-18	-10793
IGKV5-2	-10765
IGLV5-45	-10764
IGLV1-40	-10748
IGLV1-44	-10737
IGLV3-25	-10735
IGLV3-27	-10722
IGLC1	-10709
IGLV4-69	-10707
IGLV3-21	-10693
IGLV1-36	-10689
IGLV1-47	-10672
IGLV6-57	-10655
IGKV4-1	-10646
IGKV2-30	-10624
IGHV3-23	-10617
IGHV2-5	-10606
IGKV1-17	-10600
IGKV3-11	-10566
IGHG3	-10545
IGHG1	-10504
IGLV4-60	-10497
IGKV1-5	-10469
IGLV5-37	-10417
IGHV4-34	-10407
IGHV1-46	-10406
IGLV3-19	-10372
IGKV3-15	-10313
IGKV3-20	-10300
WIPF3	-10297
IGKV1D-39	-9965
IGKV1-12	-9925
IGHV3-11	-9849
IGHV1-2	-9703
IGHV3-48	-9695
IGHV2-70	-9600
IGKV1-16	-9486
CD3G	-9464
IGKV2D-40	-9270
IGKC	-9161
IGHV4-59	-8996
WAS	-8884
IGKV1D-16	-8851
VAV1	-8673
FGR	-8592
IGHV4-39	-8439
CD247	-8130
BTK	-7776
IGLC7	-7752
IGHG4	-7204
FCGR3A	-7081
WASF3	-6883
SYK	-6752
MYH9	-6652
ACTB	-6627
NCKAP1L	-6446
ARPC1B	-6441
GRB2	-6402
HCK	-6369
MAPK1	-5806
ELMO2	-4908
ARPC4	-4772
MYO9B	-4302
NCKIPSD	-4119
WASF2	-4010
IGKV2D-28	-3452
WASF1	-3160
WIPF2	-3140
ARPC1A	-3033
IGHV1-69	-2950
ARPC2	-1824
ABL1	-1394
IGKV1-33	-1353
ACTR3	-1117
LYN	-973
IGKV1-39	-666
MAPK3	-640
ARPC3	-538
MYH2	-289
SRC	116
BRK1	703
VAV3	765
ELMO1	951
ARPC5	990
CDC42	1019
WIPF1	1228
MYO1C	1470
ABI1	1553
CYFIP2	1697
RAC1	1751
MYO5A	2084
ACTR2	2139
NCK1	2702
IGKV3D-20	2798
FYN	2820
VAV2	2828
CRK	3232
ACTG1	3525
WASL	6292
BAIAP2	6532
NCKAP1	6584
PTK2	6843
CYFIP1	6961
DOCK1	7071
YES1	7207
ABI2	7835
MYO10	9031

---

Parasite infection

Parasite infection

	835
set	Parasite infection
setSize	127
pANOVA	5.96e-21
s.dist	-0.482
p.adjustANOVA	4.81e-19

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795
IGLV2-18	-10793
IGKV5-2	-10765
IGLV5-45	-10764
IGLV1-40	-10748
IGLV1-44	-10737
IGLV3-25	-10735
IGLV3-27	-10722
IGLC1	-10709
IGLV4-69	-10707
IGLV3-21	-10693
IGLV1-36	-10689
IGLV1-47	-10672
IGLV6-57	-10655
IGKV4-1	-10646
IGKV2-30	-10624
IGHV3-23	-10617
IGHV2-5	-10606
IGKV1-17	-10600
IGKV3-11	-10566
IGHG3	-10545
IGHG1	-10504
IGLV4-60	-10497
IGKV1-5	-10469
IGLV5-37	-10417
IGHV4-34	-10407
IGHV1-46	-10406
IGLV3-19	-10372
IGKV3-15	-10313
IGKV3-20	-10300
WIPF3	-10297
IGKV1D-39	-9965
IGKV1-12	-9925
IGHV3-11	-9849
IGHV1-2	-9703
IGHV3-48	-9695
IGHV2-70	-9600
IGKV1-16	-9486
CD3G	-9464
IGKV2D-40	-9270
IGKC	-9161
IGHV4-59	-8996
WAS	-8884
IGKV1D-16	-8851
VAV1	-8673
FGR	-8592
IGHV4-39	-8439
CD247	-8130
BTK	-7776
IGLC7	-7752
IGHG4	-7204
FCGR3A	-7081
WASF3	-6883
SYK	-6752
MYH9	-6652
ACTB	-6627
NCKAP1L	-6446
ARPC1B	-6441
GRB2	-6402
HCK	-6369
MAPK1	-5806
ELMO2	-4908
ARPC4	-4772
MYO9B	-4302
NCKIPSD	-4119
WASF2	-4010
IGKV2D-28	-3452
WASF1	-3160
WIPF2	-3140
ARPC1A	-3033
IGHV1-69	-2950
ARPC2	-1824
ABL1	-1394
IGKV1-33	-1353
ACTR3	-1117
LYN	-973
IGKV1-39	-666
MAPK3	-640
ARPC3	-538
MYH2	-289
SRC	116
BRK1	703
VAV3	765
ELMO1	951
ARPC5	990
CDC42	1019
WIPF1	1228
MYO1C	1470
ABI1	1553
CYFIP2	1697
RAC1	1751
MYO5A	2084
ACTR2	2139
NCK1	2702
IGKV3D-20	2798
FYN	2820
VAV2	2828
CRK	3232
ACTG1	3525
WASL	6292
BAIAP2	6532
NCKAP1	6584
PTK2	6843
CYFIP1	6961
DOCK1	7071
YES1	7207
ABI2	7835
MYO10	9031

---

Regulation of actin dynamics for phagocytic cup formation

Regulation of actin dynamics for phagocytic cup formation

	1036
set	Regulation of actin dynamics for phagocytic cup formation
setSize	129
pANOVA	2.44e-20
s.dist	-0.471
p.adjustANOVA	1.82e-18

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795
IGLV2-18	-10793
IGKV5-2	-10765
IGLV5-45	-10764
IGLV1-40	-10748
IGLV1-44	-10737
IGLV3-25	-10735
IGLV3-27	-10722
IGLC1	-10709
IGLV4-69	-10707
IGLV3-21	-10693
IGLV1-36	-10689
IGLV1-47	-10672
IGLV6-57	-10655
IGKV4-1	-10646
IGKV2-30	-10624
IGHV3-23	-10617
IGHV2-5	-10606
IGKV1-17	-10600
IGKV3-11	-10566
IGHG3	-10545
IGHG1	-10504
IGLV4-60	-10497
IGKV1-5	-10469
IGLV5-37	-10417
IGHV4-34	-10407
IGHV1-46	-10406
IGLV3-19	-10372
IGKV3-15	-10313
IGKV3-20	-10300
WIPF3	-10297
IGKV1D-39	-9965
IGKV1-12	-9925
IGHV3-11	-9849
IGHV1-2	-9703
IGHV3-48	-9695
IGHV2-70	-9600
IGKV1-16	-9486
CD3G	-9464
IGKV2D-40	-9270
IGKC	-9161
IGHV4-59	-8996
WAS	-8884
IGKV1D-16	-8851
VAV1	-8673
IGHV4-39	-8439
CD247	-8130
BTK	-7776
IGLC7	-7752
IGHG4	-7204
FCGR3A	-7081
WASF3	-6883
SYK	-6752
MYH9	-6652
ACTB	-6627
NCKAP1L	-6446
ARPC1B	-6441
GRB2	-6402
MAPK1	-5806
PAK1	-5016
ELMO2	-4908
ARPC4	-4772
CFL1	-4675
MYO9B	-4302
NCKIPSD	-4119
WASF2	-4010
IGKV2D-28	-3452
WASF1	-3160
WIPF2	-3140
ARPC1A	-3033
IGHV1-69	-2950
NF2	-2396
FCGR1A	-2052
ARPC2	-1824
ABL1	-1394
IGKV1-33	-1353
ACTR3	-1117
IGKV1-39	-666
MAPK3	-640
ARPC3	-538
MYH2	-289
BRK1	703
FCGR2A	712
VAV3	765
ELMO1	951
ARPC5	990
CDC42	1019
WIPF1	1228
MYO1C	1470
ABI1	1553
CYFIP2	1697
RAC1	1751
MYO5A	2084
ACTR2	2139
NCK1	2702
IGKV3D-20	2798
VAV2	2828
HSP90AA1	2976
CRK	3232
HSP90AB1	3401
ACTG1	3525
LIMK1	4536
WASL	6292
BAIAP2	6532
NCKAP1	6584
PTK2	6843
CYFIP1	6961
DOCK1	7071
ABI2	7835
MYO10	9031

---

FCGR3A-mediated IL10 synthesis

FCGR3A-mediated IL10 synthesis

	380
set	FCGR3A-mediated IL10 synthesis
setSize	104
pANOVA	2.51e-20
s.dist	-0.524
p.adjustANOVA	1.82e-18

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795
IGLV2-18	-10793
IGKV5-2	-10765
IGLV5-45	-10764
IGLV1-40	-10748
IGLV1-44	-10737
IGLV3-25	-10735
IGLV3-27	-10722
IGLC1	-10709
IGLV4-69	-10707
IGLV3-21	-10693
IGLV1-36	-10689
IGLV1-47	-10672
IGLV6-57	-10655
IGKV4-1	-10646
IGKV2-30	-10624
IGHV3-23	-10617
IGHV2-5	-10606
IGKV1-17	-10600
IGKV3-11	-10566
IGHG3	-10545
IGHG1	-10504
IGLV4-60	-10497
IGKV1-5	-10469
IGLV5-37	-10417
IGHV4-34	-10407
IGHV1-46	-10406
IGLV3-19	-10372
IGKV3-15	-10313
IGKV3-20	-10300
IGKV1D-39	-9965
IGKV1-12	-9925
IGHV3-11	-9849
IGHV1-2	-9703
IGHV3-48	-9695
IGHV2-70	-9600
PRKAR2B	-9494
IGKV1-16	-9486
CD3G	-9464
IGKV2D-40	-9270
IGKC	-9161
IGHV4-59	-8996
IGKV1D-16	-8851
FGR	-8592
IGHV4-39	-8439
CD247	-8130
IGLC7	-7752
IGHG4	-7204
FCGR3A	-7081
SYK	-6752
HCK	-6369
PLCG2	-6329
ADCY7	-5766
ADCY5	-5366
IGKV2D-28	-3452
ADCY3	-3102
IGHV1-69	-2950
FCGR1A	-2052
IGKV1-33	-1353
PRKACA	-1109
LYN	-973
IGKV1-39	-666
SRC	116
CALM1	172
FCGR2A	712
PLCG1	2063
ADCY4	2528
IGKV3D-20	2798
FYN	2820
PRKAR1B	2933
PRKACB	3303
CREB1	3358
ADCY6	3410
AHCYL1	4052
PRKAR2A	5114
ADCY2	5254
PRKX	5301
ADCY9	5457
ITPR1	6224
ITPR3	6415
ITPR2	7099
YES1	7207
PRKAR1A	7315
ADCY1	8733
IL10	9201

---

Eukaryotic Translation Elongation

Eukaryotic Translation Elongation

	368
set	Eukaryotic Translation Elongation
setSize	93
pANOVA	5.43e-17
s.dist	0.502
p.adjustANOVA	3.75e-15

Top enriched genes

Top 20 genes

GeneID	Gene Rank
EEF1A2	8503
RPSA	7908
RPL9	7848
RPS27L	6864
RPL41	6462
EEF1G	6165
RPS2	6089
EEF1A1P5	6039
RPS9	6020
RPL18A	5926
EEF1A1	5862
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
RPS3A	5482
RPL36A	5419
EEF2	5402
RPL7	5370
RPL37A	5366

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
EEF1A2	8503
RPSA	7908
RPL9	7848
RPS27L	6864
RPL41	6462
EEF1G	6165
RPS2	6089
EEF1A1P5	6039
RPS9	6020
RPL18A	5926
EEF1A1	5862
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
RPS3A	5482
RPL36A	5419
EEF2	5402
RPL7	5370
RPL37A	5366
RPL23A	5347
RPL13A	5213
RPL13	5185
RPS16	5179
RPL15	5149
RPL4	5091
RPL36AL	5042
RPS11	4999
RPS19	4946
RPL32	4893
RPL39	4878
RPL29	4831
RPL31	4824
RPS10	4796
RPL19	4738
RPS27A	4555
EEF1D	4542
RPL28	4540
RPL18	4499
RPL7A	4483
EEF1B2	4480
RPL3	4426
RPL17	4292
RPS3	4276
RPL27	4270
RPL23	4262
RPL6	4249
RPL35A	4246
RPS18	4239
RPS23	4200
RPL10A	4189
RPS17	4171
RPS5	4154
RPL12	4132
RPS8	4115
RPL8	4000
RPL14	3947
RPS24	3930
RPL34	3928
RPL37	3888
RPS25	3886
RPS7	3878
RPL26	3817
RPL35	3741
RPS12	3713
RPS15A	3668
RPL10	3638
RPL38	3564
RPL36	3513
RPS6	3469
RPS21	3461
RPL30	3402
RPS15	3394
FAU	3307
RPL22	3284
RPL21	3212
RPS29	3177
RPL5	3062
RPL22L1	3056
RPS27	3034
RPS20	2909
RPLP1	2674
RPL27A	2608
RPS4Y1	2516
RPL11	2004
RPLP2	1969
RPS28	1779
RPL26L1	1510
RPS14	1220
RPS4X	120
UBA52	75
RPL3L	-1445
RPS26	-5402

---

Nervous system development

Nervous system development

	757
set	Nervous system development
setSize	513
pANOVA	1.62e-16
s.dist	0.213
p.adjustANOVA	1.07e-14

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ANK3	9178
RND1	9173
ROBO2	9154
EGR2	9108
SH3GL2	9093
PFN2	9056
MYO10	9031
DOK6	9007
ITGA2	8913
WWTR1	8894
TRPC6	8822
DOK5	8772
NGEF	8744
SLIT2	8717
RPS6KA6	8716
NCAM1	8711
ITGAV	8674
NTN1	8671
SHC3	8665
SEMA5A	8650

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ANK3	9178
RND1	9173
ROBO2	9154
EGR2	9108
SH3GL2	9093
PFN2	9056
MYO10	9031
DOK6	9007
ITGA2	8913
WWTR1	8894
TRPC6	8822
DOK5	8772
NGEF	8744
SLIT2	8717
RPS6KA6	8716
NCAM1	8711
ITGAV	8674
NTN1	8671
SHC3	8665
SEMA5A	8650
SDC2	8628
FLRT3	8608
NRP2	8596
SEMA3E	8592
ROBO1	8562
PRKCA	8540
RHOC	8521
EPHA2	8482
SCN2B	8412
MSI1	8358
ENAH	8320
UNC5B	8292
EFNB3	8251
UNC5C	8230
SRGAP3	8203
ABL2	8168
SCD5	8111
ITGA5	8051
CACNA1D	8040
SEMA6D	8031
ITGA10	8010
KALRN	7990
SHTN1	7916
RPSA	7908
NEO1	7892
GFRA1	7874
TRPC4	7857
CYP51A1	7850
RPL9	7848
FARP2	7847
EPHA3	7778
DPYSL4	7777
PIK3R3	7755
EFNB2	7754
EFNA5	7685
MET	7591
GPC1	7465
ADAM10	7409
ADGRG6	7400
SRGAP1	7396
PSMB5	7356
RDX	7257
PLXNA2	7217
COL4A1	7213
YES1	7207
NAB2	7201
SCN4B	7127
SHC1	7085
DOCK1	7071
DPYSL3	7068
ARHGAP39	7018
LHX4	6937
CACNA1C	6871
RPS27L	6864
GFRA2	6847
PTK2	6843
RPS6KA3	6833
CDK5	6809
ABLIM1	6780
GSPT2	6768
HMGCR	6745
AKAP5	6716
NRCAM	6549
DLG1	6499
RPL41	6462
ITGB1	6439
WASL	6292
SEM1	6281
COL6A2	6270
SCN1B	6122
RPS2	6089
TIAM1	6053
FRS2	6026
RPS9	6020
RHOB	5934
NAB1	5933
RPL18A	5926
PMP22	5921
HSPA8	5871
RPS13	5739
RPLP0	5695
RPL24	5693
EPHA4	5682
CACNB4	5659
CLTA	5641
EFNA1	5637
CRMP1	5634
RPL39L	5631
ELOB	5627
RPS3A	5482
PLXNA1	5470
COL6A1	5449
RPL36A	5419
CSNK2A2	5397
RPL7	5370
RPL37A	5366
RPL23A	5347
DOK4	5311
HRAS	5288
SEMA7A	5268
EPHB1	5249
RPL13A	5213
RPL13	5185
RPS16	5179
GAB1	5161
MYH10	5152
RPL15	5149
PRKAR2A	5114
RPL4	5091
PSME2	5088
DSCAML1	5077
NRAS	5076
RPL36AL	5042
RPS11	4999
SPTBN5	4973
SRGAP2	4964
PIK3CA	4947
RPS19	4946
RPL32	4893
YAP1	4884
RPL39	4878
RPL29	4831
RPL31	4824
ST8SIA4	4814
RPS10	4796
TRPC1	4785
RPL19	4738
CNTN1	4671
ELOC	4667
FGFR1	4638
ERBB2	4628
ITGA9	4558
RPS27A	4555
RPL28	4540
ABLIM2	4539
LIMK1	4536
DAG1	4533
ETF1	4529
RPL18	4499
RPL7A	4483
ITGA1	4457
SPTAN1	4430
RPL3	4426
EZR	4396
PLXNA3	4379
PRNP	4354
PSMA2	4316
RPL17	4292
RPS3	4276
RPL27	4270
RPL23	4262
RPL6	4249
RPL35A	4246
RPS18	4239
RPS23	4200
RPL10A	4189
RPS17	4171
RPS5	4154
RPL12	4132
PLXNB1	4116
RPS8	4115
SIAH1	4064
COL6A3	4021
COL4A2	4008
RPL8	4000
TRIO	3987
UTRN	3984
PSENEN	3970
RPL14	3947
CXCL12	3938
RPS24	3930
RPL34	3928
EPHB4	3918
EFNB1	3902
COL9A3	3899
RPL37	3888
RPS25	3886
RPS7	3878
RPL26	3817
KRAS	3793
SCN4A	3748
RPL35	3741
ARHGEF12	3727
RPS12	3713
RPS15A	3668
CLTB	3663
RPL10	3638
PLXND1	3583
RPL38	3564
ACTG1	3525
PSMD10	3520
RPL36	3513
RPS6	3469
RPS21	3461
PSMA5	3448
SHANK3	3441
NRP1	3435
NCK2	3415
RPL30	3402
HSP90AB1	3401
RPS15	3394
CREB1	3358
NTN4	3335
DLG4	3329
DLG3	3317
FAU	3307
PRKACB	3303
SDCBP	3297
LAMC1	3285
RPL22	3284
RPL21	3212
RPS29	3177
EFNA4	3102
MAPK8	3067
RPL5	3062
RPL22L1	3056
PSMA3	3043
RPS27	3034
GRB10	3025
HSP90AA1	2976
MMP9	2968
ROCK2	2967
CACNA1H	2957
RRAS	2921
RPS20	2909
EPHB3	2877
VAV2	2828
FYN	2820
NCK1	2702
RPLP1	2674
SCN2A	2631
MYL6	2625
RPL27A	2608
SCN11A	2598
PAK4	2593
UBC	2572
RPS4Y1	2516
EPHA7	2515
PAK2	2496
ARHGEF28	2454
LAMB1	2429
RGMB	2363
RASA1	2313
CLASP2	2290
PSMD8	2211
PSMD14	2194
ARHGAP35	2168
ACTR2	2139
MYH11	2133
PSMA4	2112
PLCG1	2063
RHOA	2032
RPL11	2004
RPLP2	1969
PIK3R1	1940
PSMB4	1921
ITGB3	1908
HDAC2	1907
PSME3	1870
PSMD13	1835
NCBP1	1828
RPS28	1779
PTPN11	1777
RAC1	1751
APH1B	1738
PIK3CB	1574
PSME1	1537
RPL26L1	1510
PAK6	1445
UNC5A	1355
MYL12B	1306
AP2S1	1304
CLTC	1234
MAPK11	1224
RPS14	1220
PPP3CB	1050
NFASC	1025
CDC42	1019
ARPC5	990
EPHB2	956
ALCAM	891
PSMA6	883
DNM3	864
SCN3B	834
RPS6KA2	831
SCN3A	790
VAV3	765
CD72	736
NCBP2	687
ARHGEF7	625
TRPC3	590
PTPRC	563
PSMD1	535
PRX	395
SCN1A	366
APH1A	346
ARHGEF11	339
PIP5K1C	248
ARTN	159
RPS4X	120
SRC	116
UBA52	75
PSMB7	43
CACNB3	32
PSMB6	-57
PDLIM7	-89
SOS2	-191
PSMC3	-201
PSMB9	-203
PLXNB3	-244
PSMB1	-262
VLDLR	-276
RPS6KA5	-310
PSMD12	-334
PSME4	-458
PSMA1	-487
CSNK2A1	-520
ARPC3	-538
MAGOHB	-551
AGRN	-570
MYH14	-618
MAPK3	-640
DNM1	-701
PSMC6	-713
PSMD5	-770
RANBP9	-858
PITPNA	-900
MYL12A	-911
LYN	-973
MAGOH	-1001
TEAD1	-1017
GIT1	-1058
EVL	-1068
PRKACA	-1109
ACTR3	-1117
CUL2	-1189
CLASP1	-1213
SOS1	-1232
PSMB8	-1241
TYROBP	-1313
DPYSL2	-1342
CNTNAP1	-1362
ABL1	-1394
RPL3L	-1445
SCN8A	-1490
CACNB1	-1590
SPTBN4	-1668
GSPT1	-1686
EIF4A3	-1789
USP33	-1799
ARPC2	-1824
ADGRV1	-1856
PSMC2	-2035
CACNA1I	-2082
TREM2	-2101
MSN	-2114
ABLIM3	-2145
SMARCA4	-2206
ROCK1	-2243
AP2B1	-2296
GSK3B	-2330
PSMB10	-2349
PSMC1	-2353
AP2M1	-2365
PSMB3	-2369
PSPN	-2456
PSMD6	-2501
RBX1	-2533
RBM8A	-2541
PSMA7	-2633
UBB	-2665
PSEN2	-2704
AP2A2	-2709
HOXA2	-2780
SEMA3A	-2806
PLXNC1	-2932
ARPC1A	-3033
MMP2	-3039
GAB2	-3076
SEMA4D	-3110
UPF2	-3168
SPTBN1	-3307
PSEN1	-3333
GRIN2B	-3420
NUMB	-3434
CAP1	-3436
PSMD4	-3492
LIMK2	-3521
MYL9	-3598
MAP2K1	-3701
PSMB2	-3751
DOK1	-3803
MAPK7	-3865
RNPS1	-3910
EIF4G1	-3934
CASC3	-4082
CSNK2B	-4147
ITSN1	-4254
RPS6KA4	-4266
MYO9B	-4302
PIK3R2	-4348
SLIT3	-4470
MAPK12	-4620
PSMC5	-4664
CFL1	-4675
MAPK13	-4730
ARPC4	-4772
TLN1	-4792
ZSWIM8	-4900
PAK1	-5016
PSMD7	-5071
MAP2K2	-5121
PABPC1	-5187
MAPK14	-5334
LYPLA2	-5400
RPS26	-5402
MBP	-5415
PSMD2	-5529
ROBO3	-5535
PSMD3	-5686
RGMA	-5701
CD24	-5710
MAPK1	-5806
EPHA1	-5887
PSMD11	-5926
PSMF1	-6034
UPF3A	-6253
RAP1GAP	-6288
PSMD9	-6396
GRB2	-6402
ARPC1B	-6441
NCSTN	-6510
SCN9A	-6517
EGFR	-6577
ACTB	-6627
MYH9	-6652
SEMA6A	-6677
VASP	-6826
SH3KBP1	-6879
KIF4A	-6923
PSMC4	-6992
EFNA3	-7014
KCNQ3	-7047
CACNB2	-7054
MPZ	-7160
PIK3CD	-7175
SPTA1	-7256
SPTBN2	-7281
SREBF2	-7451
PFN1	-7552
DNM2	-7699
PLXNA4	-7704
SLIT1	-7717
SIAH2	-7829
PTPRA	-7886
PRKCQ	-7988
AP2A1	-8034
RET	-8214
ANK1	-8328
ANK2	-8329
CXCR4	-8632
COL9A2	-8654
NELL2	-8728
RPS6KA1	-8768
DOK2	-8797
CHL1	-8805
FES	-8852
CAP2	-8853
LDB1	-8870
EPHB6	-8880
SEMA4A	-9060
AGAP2	-9105
SPTB	-9120
PAK3	-9138
CLTCL1	-9153
UPF3B	-9197
LAMA1	-9199
L1CAM	-9726
COL4A4	-10003
CNTN2	-10101
CACNA1G	-10182
GAP43	-10208
COL9A1	-10245
CDK5R1	-10308
COL4A3	-10446
ITGA2B	-10608
SCN7A	-10726
IRS2	-10805
DRP2	-10810
EPHA10	-10860
COL4A5	-10902
LAMA2	-10937
RELN	-10963

---

FCERI mediated NF-kB activation

FCERI mediated NF-kB activation

	378
set	FCERI mediated NF-kB activation
setSize	141
pANOVA	1.88e-16
s.dist	-0.401
p.adjustANOVA	1.19e-14

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795
IGLV2-18	-10793

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795
IGLV2-18	-10793
IGKV5-2	-10765
IGLV5-45	-10764
IGLV1-40	-10748
IGLV1-44	-10737
IGLV3-25	-10735
IGLV3-27	-10722
IGLC1	-10709
IGLV4-69	-10707
IGLV3-21	-10693
IGLV1-36	-10689
IGLV1-47	-10672
IGLV6-57	-10655
IGKV4-1	-10646
IGKV2-30	-10624
IGHV3-23	-10617
IGHV2-5	-10606
IGKV1-17	-10600
IGKV3-11	-10566
IGLV4-60	-10497
IGKV1-5	-10469
IGLV5-37	-10417
IGHV4-34	-10407
IGHV1-46	-10406
IGLV3-19	-10372
IGKV3-15	-10313
IGKV3-20	-10300
IGKV1D-39	-9965
IGKV1-12	-9925
IGHV3-11	-9849
IGHV1-2	-9703
IGHV3-48	-9695
IGHV2-70	-9600
IGKV1-16	-9486
RASGRP2	-9374
IGKV2D-40	-9270
IGKC	-9161
IGHV4-59	-8996
IGKV1D-16	-8851
IGHE	-8557
IGHV4-39	-8439
RASGRP4	-8347
IKBKG	-8285
CARD11	-8095
PRKCQ	-7988
IGLC7	-7752
NFKBIA	-7730
PSMC4	-6992
CDC34	-6980
UBE2V1	-6413
PSMD9	-6396
PSMF1	-6034
PSMD11	-5926
PSMD3	-5686
RASGRP1	-5552
PSMD2	-5529
TRAF6	-5526
IKBKB	-5150
PSMD7	-5071
PSMC5	-4664
PSMB2	-3751
TAB1	-3608
PSMD4	-3492
IGKV2D-28	-3452
IGHV1-69	-2950
UBB	-2665
PSMA7	-2633
PSMD6	-2501
PSMB3	-2369
PSMC1	-2353
PSMB10	-2349
PSMC2	-2035
CUL1	-1579
NFKB1	-1447
IGKV1-33	-1353
PSMB8	-1241
CHUK	-1047
LYN	-973
PSMD5	-770
PSMC6	-713
IGKV1-39	-666
PSMA1	-487
PSME4	-458
PDPK1	-364
PSMD12	-334
PSMB1	-262
PSMB9	-203
PSMC3	-201
PSMB6	-57
TAB3	24
PSMB7	43
UBA52	75
BTRC	85
PSMD1	535
PSMA6	883
SKP1	1522
PSME1	1537
PSMD13	1835
PSME3	1870
PSMB4	1921
MAP3K7	2009
PSMA4	2112
PSMD14	2194
PSMD8	2211
UBE2D2	2232
UBC	2572
IGKV3D-20	2798
MALT1	2831
PSMA3	3043
PSMA5	3448
PSMD10	3520
UBE2N	4169
PSMA2	4316
TAB2	4482
RPS27A	4555
PSME2	5088
RELA	5093
FBXW11	6219
SEM1	6281
UBE2D1	6535
PSMB5	7356
BCL10	7455

---

Fcgamma receptor (FCGR) dependent phagocytosis

Fcgamma receptor (FCGR) dependent phagocytosis

	401
set	Fcgamma receptor (FCGR) dependent phagocytosis
setSize	154
pANOVA	6.3e-16
s.dist	-0.377
p.adjustANOVA	3.81e-14

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795
IGLV2-18	-10793
IGKV5-2	-10765
IGLV5-45	-10764
IGLV1-40	-10748
IGLV1-44	-10737
IGLV3-25	-10735
IGLV3-27	-10722
IGLC1	-10709
IGLV4-69	-10707
IGLV3-21	-10693
IGLV1-36	-10689
IGLV1-47	-10672
IGLV6-57	-10655
IGKV4-1	-10646
IGKV2-30	-10624
IGHV3-23	-10617
IGHV2-5	-10606
IGKV1-17	-10600
IGKV3-11	-10566
IGHG3	-10545
IGHG1	-10504
IGLV4-60	-10497
IGKV1-5	-10469
IGLV5-37	-10417
IGHV4-34	-10407
IGHV1-46	-10406
IGLV3-19	-10372
IGKV3-15	-10313
IGKV3-20	-10300
WIPF3	-10297
IGKV1D-39	-9965
IGKV1-12	-9925
IGHV3-11	-9849
IGHV1-2	-9703
IGHV3-48	-9695
IGHV2-70	-9600
IGKV1-16	-9486
CD3G	-9464
IGKV2D-40	-9270
IGKC	-9161
IGHV4-59	-8996
WAS	-8884
IGKV1D-16	-8851
VAV1	-8673
FGR	-8592
PRKCD	-8561
PLD4	-8487
IGHV4-39	-8439
PLA2G6	-8156
CD247	-8130
BTK	-7776
IGLC7	-7752
IGHG4	-7204
FCGR3A	-7081
WASF3	-6883
SYK	-6752
MYH9	-6652
ACTB	-6627
NCKAP1L	-6446
ARPC1B	-6441
GRB2	-6402
HCK	-6369
PLCG2	-6329
MAPK1	-5806
PAK1	-5016
ELMO2	-4908
ARPC4	-4772
CFL1	-4675
PIK3R2	-4348
MYO9B	-4302
NCKIPSD	-4119
WASF2	-4010
PLPP4	-3656
IGKV2D-28	-3452
WASF1	-3160
WIPF2	-3140
ARPC1A	-3033
IGHV1-69	-2950
NF2	-2396
FCGR1A	-2052
ARPC2	-1824
ABL1	-1394
IGKV1-33	-1353
ACTR3	-1117
LYN	-973
IGKV1-39	-666
MAPK3	-640
ARPC3	-538
MYH2	-289
PLD2	-216
SRC	116
PLPP5	179
BRK1	703
FCGR2A	712
VAV3	765
ELMO1	951
ARPC5	990
CDC42	1019
WIPF1	1228
MYO1C	1470
ABI1	1553
PIK3CB	1574
CYFIP2	1697
RAC1	1751
PIK3R1	1940
PLCG1	2063
MYO5A	2084
ACTR2	2139
NCK1	2702
IGKV3D-20	2798
FYN	2820
VAV2	2828
HSP90AA1	2976
CRK	3232
PLD1	3384
HSP90AB1	3401
ACTG1	3525
AHCYL1	4052
LIMK1	4536
PLD3	4574
PIK3CA	4947
ITPR1	6224
WASL	6292
ITPR3	6415
BAIAP2	6532
NCKAP1	6584
PTK2	6843
CYFIP1	6961
DOCK1	7071
ITPR2	7099
YES1	7207
ABI2	7835
PRKCE	7875
MYO10	9031

---

Axon guidance

Axon guidance

	101
set	Axon guidance
setSize	492
pANOVA	1.04e-15
s.dist	0.211
p.adjustANOVA	6.02e-14

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ANK3	9178
RND1	9173
ROBO2	9154
SH3GL2	9093
PFN2	9056
MYO10	9031
DOK6	9007
ITGA2	8913
TRPC6	8822
DOK5	8772
NGEF	8744
SLIT2	8717
RPS6KA6	8716
NCAM1	8711
ITGAV	8674
NTN1	8671
SHC3	8665
SEMA5A	8650
SDC2	8628
FLRT3	8608

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ANK3	9178
RND1	9173
ROBO2	9154
SH3GL2	9093
PFN2	9056
MYO10	9031
DOK6	9007
ITGA2	8913
TRPC6	8822
DOK5	8772
NGEF	8744
SLIT2	8717
RPS6KA6	8716
NCAM1	8711
ITGAV	8674
NTN1	8671
SHC3	8665
SEMA5A	8650
SDC2	8628
FLRT3	8608
NRP2	8596
SEMA3E	8592
ROBO1	8562
PRKCA	8540
RHOC	8521
EPHA2	8482
SCN2B	8412
MSI1	8358
ENAH	8320
UNC5B	8292
EFNB3	8251
UNC5C	8230
SRGAP3	8203
ABL2	8168
ITGA5	8051
CACNA1D	8040
SEMA6D	8031
ITGA10	8010
KALRN	7990
SHTN1	7916
RPSA	7908
NEO1	7892
GFRA1	7874
TRPC4	7857
RPL9	7848
FARP2	7847
EPHA3	7778
DPYSL4	7777
PIK3R3	7755
EFNB2	7754
EFNA5	7685
MET	7591
GPC1	7465
ADAM10	7409
SRGAP1	7396
PSMB5	7356
RDX	7257
PLXNA2	7217
COL4A1	7213
YES1	7207
SCN4B	7127
SHC1	7085
DOCK1	7071
DPYSL3	7068
ARHGAP39	7018
LHX4	6937
CACNA1C	6871
RPS27L	6864
GFRA2	6847
PTK2	6843
RPS6KA3	6833
CDK5	6809
ABLIM1	6780
GSPT2	6768
AKAP5	6716
NRCAM	6549
DLG1	6499
RPL41	6462
ITGB1	6439
WASL	6292
SEM1	6281
COL6A2	6270
SCN1B	6122
RPS2	6089
TIAM1	6053
FRS2	6026
RPS9	6020
RHOB	5934
RPL18A	5926
HSPA8	5871
RPS13	5739
RPLP0	5695
RPL24	5693
EPHA4	5682
CACNB4	5659
CLTA	5641
EFNA1	5637
CRMP1	5634
RPL39L	5631
ELOB	5627
RPS3A	5482
PLXNA1	5470
COL6A1	5449
RPL36A	5419
CSNK2A2	5397
RPL7	5370
RPL37A	5366
RPL23A	5347
DOK4	5311
HRAS	5288
SEMA7A	5268
EPHB1	5249
RPL13A	5213
RPL13	5185
RPS16	5179
GAB1	5161
MYH10	5152
RPL15	5149
PRKAR2A	5114
RPL4	5091
PSME2	5088
DSCAML1	5077
NRAS	5076
RPL36AL	5042
RPS11	4999
SPTBN5	4973
SRGAP2	4964
PIK3CA	4947
RPS19	4946
RPL32	4893
RPL39	4878
RPL29	4831
RPL31	4824
ST8SIA4	4814
RPS10	4796
TRPC1	4785
RPL19	4738
CNTN1	4671
ELOC	4667
FGFR1	4638
ERBB2	4628
ITGA9	4558
RPS27A	4555
RPL28	4540
ABLIM2	4539
LIMK1	4536
DAG1	4533
ETF1	4529
RPL18	4499
RPL7A	4483
ITGA1	4457
SPTAN1	4430
RPL3	4426
EZR	4396
PLXNA3	4379
PRNP	4354
PSMA2	4316
RPL17	4292
RPS3	4276
RPL27	4270
RPL23	4262
RPL6	4249
RPL35A	4246
RPS18	4239
RPS23	4200
RPL10A	4189
RPS17	4171
RPS5	4154
RPL12	4132
PLXNB1	4116
RPS8	4115
SIAH1	4064
COL6A3	4021
COL4A2	4008
RPL8	4000
TRIO	3987
PSENEN	3970
RPL14	3947
CXCL12	3938
RPS24	3930
RPL34	3928
EPHB4	3918
EFNB1	3902
COL9A3	3899
RPL37	3888
RPS25	3886
RPS7	3878
RPL26	3817
KRAS	3793
SCN4A	3748
RPL35	3741
ARHGEF12	3727
RPS12	3713
RPS15A	3668
CLTB	3663
RPL10	3638
PLXND1	3583
RPL38	3564
ACTG1	3525
PSMD10	3520
RPL36	3513
RPS6	3469
RPS21	3461
PSMA5	3448
SHANK3	3441
NRP1	3435
NCK2	3415
RPL30	3402
HSP90AB1	3401
RPS15	3394
CREB1	3358
NTN4	3335
DLG4	3329
DLG3	3317
FAU	3307
PRKACB	3303
SDCBP	3297
LAMC1	3285
RPL22	3284
RPL21	3212
RPS29	3177
EFNA4	3102
MAPK8	3067
RPL5	3062
RPL22L1	3056
PSMA3	3043
RPS27	3034
GRB10	3025
HSP90AA1	2976
MMP9	2968
ROCK2	2967
CACNA1H	2957
RRAS	2921
RPS20	2909
EPHB3	2877
VAV2	2828
FYN	2820
NCK1	2702
RPLP1	2674
SCN2A	2631
MYL6	2625
RPL27A	2608
SCN11A	2598
PAK4	2593
UBC	2572
RPS4Y1	2516
EPHA7	2515
PAK2	2496
ARHGEF28	2454
LAMB1	2429
RGMB	2363
RASA1	2313
CLASP2	2290
PSMD8	2211
PSMD14	2194
ARHGAP35	2168
ACTR2	2139
MYH11	2133
PSMA4	2112
PLCG1	2063
RHOA	2032
RPL11	2004
RPLP2	1969
PIK3R1	1940
PSMB4	1921
ITGB3	1908
PSME3	1870
PSMD13	1835
NCBP1	1828
RPS28	1779
PTPN11	1777
RAC1	1751
APH1B	1738
PIK3CB	1574
PSME1	1537
RPL26L1	1510
PAK6	1445
UNC5A	1355
MYL12B	1306
AP2S1	1304
CLTC	1234
MAPK11	1224
RPS14	1220
PPP3CB	1050
NFASC	1025
CDC42	1019
ARPC5	990
EPHB2	956
ALCAM	891
PSMA6	883
DNM3	864
SCN3B	834
RPS6KA2	831
SCN3A	790
VAV3	765
CD72	736
NCBP2	687
ARHGEF7	625
TRPC3	590
PTPRC	563
PSMD1	535
SCN1A	366
APH1A	346
ARHGEF11	339
PIP5K1C	248
ARTN	159
RPS4X	120
SRC	116
UBA52	75
PSMB7	43
CACNB3	32
PSMB6	-57
PDLIM7	-89
SOS2	-191
PSMC3	-201
PSMB9	-203
PLXNB3	-244
PSMB1	-262
VLDLR	-276
RPS6KA5	-310
PSMD12	-334
PSME4	-458
PSMA1	-487
CSNK2A1	-520
ARPC3	-538
MAGOHB	-551
AGRN	-570
MYH14	-618
MAPK3	-640
DNM1	-701
PSMC6	-713
PSMD5	-770
RANBP9	-858
PITPNA	-900
MYL12A	-911
LYN	-973
MAGOH	-1001
GIT1	-1058
EVL	-1068
PRKACA	-1109
ACTR3	-1117
CUL2	-1189
CLASP1	-1213
SOS1	-1232
PSMB8	-1241
TYROBP	-1313
DPYSL2	-1342
CNTNAP1	-1362
ABL1	-1394
RPL3L	-1445
SCN8A	-1490
CACNB1	-1590
SPTBN4	-1668
GSPT1	-1686
EIF4A3	-1789
USP33	-1799
ARPC2	-1824
PSMC2	-2035
CACNA1I	-2082
TREM2	-2101
MSN	-2114
ABLIM3	-2145
ROCK1	-2243
AP2B1	-2296
GSK3B	-2330
PSMB10	-2349
PSMC1	-2353
AP2M1	-2365
PSMB3	-2369
PSPN	-2456
PSMD6	-2501
RBX1	-2533
RBM8A	-2541
PSMA7	-2633
UBB	-2665
PSEN2	-2704
AP2A2	-2709
HOXA2	-2780
SEMA3A	-2806
PLXNC1	-2932
ARPC1A	-3033
MMP2	-3039
GAB2	-3076
SEMA4D	-3110
UPF2	-3168
SPTBN1	-3307
PSEN1	-3333
GRIN2B	-3420
NUMB	-3434
CAP1	-3436
PSMD4	-3492
LIMK2	-3521
MYL9	-3598
MAP2K1	-3701
PSMB2	-3751
DOK1	-3803
MAPK7	-3865
RNPS1	-3910
EIF4G1	-3934
CASC3	-4082
CSNK2B	-4147
ITSN1	-4254
RPS6KA4	-4266
MYO9B	-4302
PIK3R2	-4348
SLIT3	-4470
MAPK12	-4620
PSMC5	-4664
CFL1	-4675
MAPK13	-4730
ARPC4	-4772
TLN1	-4792
ZSWIM8	-4900
PAK1	-5016
PSMD7	-5071
MAP2K2	-5121
PABPC1	-5187
MAPK14	-5334
LYPLA2	-5400
RPS26	-5402
PSMD2	-5529
ROBO3	-5535
PSMD3	-5686
RGMA	-5701
CD24	-5710
MAPK1	-5806
EPHA1	-5887
PSMD11	-5926
PSMF1	-6034
UPF3A	-6253
RAP1GAP	-6288
PSMD9	-6396
GRB2	-6402
ARPC1B	-6441
NCSTN	-6510
SCN9A	-6517
EGFR	-6577
ACTB	-6627
MYH9	-6652
SEMA6A	-6677
VASP	-6826
SH3KBP1	-6879
KIF4A	-6923
PSMC4	-6992
EFNA3	-7014
KCNQ3	-7047
CACNB2	-7054
PIK3CD	-7175
SPTA1	-7256
SPTBN2	-7281
PFN1	-7552
DNM2	-7699
PLXNA4	-7704
SLIT1	-7717
SIAH2	-7829
PTPRA	-7886
PRKCQ	-7988
AP2A1	-8034
RET	-8214
ANK1	-8328
ANK2	-8329
CXCR4	-8632
COL9A2	-8654
NELL2	-8728
RPS6KA1	-8768
DOK2	-8797
CHL1	-8805
FES	-8852
CAP2	-8853
LDB1	-8870
EPHB6	-8880
SEMA4A	-9060
AGAP2	-9105
SPTB	-9120
PAK3	-9138
CLTCL1	-9153
UPF3B	-9197
LAMA1	-9199
L1CAM	-9726
COL4A4	-10003
CNTN2	-10101
CACNA1G	-10182
GAP43	-10208
COL9A1	-10245
CDK5R1	-10308
COL4A3	-10446
ITGA2B	-10608
SCN7A	-10726
IRS2	-10805
EPHA10	-10860
COL4A5	-10902
RELN	-10963

---

Peptide chain elongation

Peptide chain elongation

	839
set	Peptide chain elongation
setSize	88
pANOVA	1.43e-15
s.dist	0.492
p.adjustANOVA	7.98e-14

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPSA	7908
RPL9	7848
RPS27L	6864
RPL41	6462
RPS2	6089
RPS9	6020
RPL18A	5926
EEF1A1	5862
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
RPS3A	5482
RPL36A	5419
EEF2	5402
RPL7	5370
RPL37A	5366
RPL23A	5347
RPL13A	5213
RPL13	5185

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPSA	7908
RPL9	7848
RPS27L	6864
RPL41	6462
RPS2	6089
RPS9	6020
RPL18A	5926
EEF1A1	5862
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
RPS3A	5482
RPL36A	5419
EEF2	5402
RPL7	5370
RPL37A	5366
RPL23A	5347
RPL13A	5213
RPL13	5185
RPS16	5179
RPL15	5149
RPL4	5091
RPL36AL	5042
RPS11	4999
RPS19	4946
RPL32	4893
RPL39	4878
RPL29	4831
RPL31	4824
RPS10	4796
RPL19	4738
RPS27A	4555
RPL28	4540
RPL18	4499
RPL7A	4483
RPL3	4426
RPL17	4292
RPS3	4276
RPL27	4270
RPL23	4262
RPL6	4249
RPL35A	4246
RPS18	4239
RPS23	4200
RPL10A	4189
RPS17	4171
RPS5	4154
RPL12	4132
RPS8	4115
RPL8	4000
RPL14	3947
RPS24	3930
RPL34	3928
RPL37	3888
RPS25	3886
RPS7	3878
RPL26	3817
RPL35	3741
RPS12	3713
RPS15A	3668
RPL10	3638
RPL38	3564
RPL36	3513
RPS6	3469
RPS21	3461
RPL30	3402
RPS15	3394
FAU	3307
RPL22	3284
RPL21	3212
RPS29	3177
RPL5	3062
RPL22L1	3056
RPS27	3034
RPS20	2909
RPLP1	2674
RPL27A	2608
RPS4Y1	2516
RPL11	2004
RPLP2	1969
RPS28	1779
RPL26L1	1510
RPS14	1220
RPS4X	120
UBA52	75
RPL3L	-1445
RPS26	-5402

---

Formation of a pool of free 40S subunits

Formation of a pool of free 40S subunits

	412
set	Formation of a pool of free 40S subunits
setSize	100
pANOVA	3e-15
s.dist	0.456
p.adjustANOVA	1.61e-13

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPSA	7908
RPL9	7848
RPS27L	6864
RPL41	6462
RPS2	6089
RPS9	6020
RPL18A	5926
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
RPS3A	5482
RPL36A	5419
RPL7	5370
RPL37A	5366
RPL23A	5347
RPL13A	5213
EIF3I	5192
RPL13	5185
RPS16	5179

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPSA	7908
RPL9	7848
RPS27L	6864
RPL41	6462
RPS2	6089
RPS9	6020
RPL18A	5926
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
RPS3A	5482
RPL36A	5419
RPL7	5370
RPL37A	5366
RPL23A	5347
RPL13A	5213
EIF3I	5192
RPL13	5185
RPS16	5179
RPL15	5149
RPL4	5091
RPL36AL	5042
RPS11	4999
RPS19	4946
RPL32	4893
RPL39	4878
RPL29	4831
RPL31	4824
RPS10	4796
RPL19	4738
RPS27A	4555
EIF1AX	4546
RPL28	4540
RPL18	4499
RPL7A	4483
RPL3	4426
EIF3E	4400
RPL17	4292
RPS3	4276
RPL27	4270
RPL23	4262
RPL6	4249
RPL35A	4246
RPS18	4239
RPS23	4200
RPL10A	4189
RPS17	4171
RPS5	4154
EIF3L	4150
RPL12	4132
RPS8	4115
RPL8	4000
RPL14	3947
RPS24	3930
RPL34	3928
RPL37	3888
RPS25	3886
RPS7	3878
RPL26	3817
RPL35	3741
RPS12	3713
RPS15A	3668
RPL10	3638
RPL38	3564
EIF3G	3561
RPL36	3513
RPS6	3469
RPS21	3461
RPL30	3402
RPS15	3394
EIF3H	3328
FAU	3307
RPL22	3284
RPL21	3212
RPS29	3177
RPL5	3062
RPL22L1	3056
RPS27	3034
RPS20	2909
EIF3J	2844
RPLP1	2674
RPL27A	2608
RPS4Y1	2516
RPL11	2004
RPLP2	1969
RPS28	1779
EIF3K	1770
EIF3M	1661
RPL26L1	1510
EIF3D	1419
RPS14	1220
EIF3C	985
RPS4X	120
UBA52	75
EIF3A	-495
RPL3L	-1445
EIF3F	-2691
RPS26	-5402
EIF3B	-6895

---

Metabolism of proteins

Metabolism of proteins

	677
set	Metabolism of proteins
setSize	1711
pANOVA	4.23e-15
s.dist	0.114
p.adjustANOVA	2.19e-13

Top enriched genes

Top 20 genes

GeneID	Gene Rank
INHBA	9192
SOCS3	9188
IL6	9183
ANK3	9178
MT-RNR2	9176
NR4A2	9175
RAB38	9172
ADAMTS4	9158
PAPPA	9145
ADAMTS9	9135
ST6GALNAC5	9134
ADAMTS1	9123
SPP1	9117
GNG4	9113
TUSC3	9111
DMBT1	9096
MT-RNR1	9091
PRND	9074
OPCML	9051
CD109	9047

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
INHBA	9192.0
SOCS3	9188.0
IL6	9183.0
ANK3	9178.0
MT-RNR2	9176.0
NR4A2	9175.0
RAB38	9172.0
ADAMTS4	9158.0
PAPPA	9145.0
ADAMTS9	9135.0
ST6GALNAC5	9134.0
ADAMTS1	9123.0
SPP1	9117.0
GNG4	9113.0
TUSC3	9111.0
DMBT1	9096.0
MT-RNR1	9091.0
PRND	9074.0
OPCML	9051.0
CD109	9047.0
CDH2	9040.0
CD55	9004.0
CPE	8991.0
LY6H	8988.0
SATB2	8986.0
SBSPON	8985.0
FN1	8982.0
THBS1	8890.0
DPP4	8879.0
KLK3	8864.0
VDR	8840.0
VWA1	8823.0
GALNT5	8783.0
TPST1	8778.0
PLAUR	8771.0
COPZ2	8767.0
GALNT17	8761.0
BGLAP	8755.0
GALNT18	8746.0
TGFBR1	8727.0
KDELR3	8691.0
MUC3A	8669.0
TIMP1	8656.0
SEMA5A	8650.0
CMA1	8634.0
SDC2	8628.0
THSD7B	8626.0
KLF4	8604.0
TUBA1A	8594.0
LMO7	8593.0
ADAMTS6	8581.0
CRHR2	8573.0
CNIH1	8561.0
ENPEP	8553.0
AREG	8544.0
ADAMTS17	8505.0
EEF1A2	8503.0
CST3	8500.0
DMP1	8497.0
GNA14	8492.0
FAM20C	8488.0
GRIA1	8456.0
IGFBP3	8455.0
MELTF	8454.0
AXIN2	8451.0
ARF4	8449.0
USP13	8422.0
PGM3	8420.0
ULBP2	8411.0
SEC23A	8409.0
LY6E	8402.0
RCN1	8397.0
FBXO2	8388.0
TMEM132A	8380.0
RNF152	8373.0
CALU	8366.0
TGFBI	8354.0
COG6	8316.0
TNC	8278.0
HIF1A	8270.0
SERPINA1	8240.0
GNGT2	8231.0
GALNT16	8227.0
MEPE	8226.0
APOE	8221.0
TMED3	8212.0
GALNT15	8190.0
MRPL17	8179.0
RAB3A	8167.0
STX1A	8158.0
UGGT2	8153.0
CTNNB1	8135.0
IGFBP7	8131.0
ARSI	8120.0
SEC24D	8115.0
KDELR2	8100.0
ADRA2A	8098.0
GNPNAT1	8095.0
LYPD5	8078.0
ARSJ	8058.0
PGAP1	8054.0
B3GNT5	8027.0
VASH2	7996.0
ARCN1	7995.0
RAB34	7979.0
NOTUM	7971.0
MATN3	7965.0
SEMA5B	7956.0
CPA3	7954.0
GALNT3	7951.0
COL7A1	7946.0
TGFA	7915.0
RPSA	7908.0
GOLM1	7905.0
UBE2Q2	7895.0
NRN1	7863.0
FOLR1	7855.0
RPL9	7848.0
FAM20A	7832.0
GNB4	7820.0
GCNT4	7815.0
EVA1A	7788.0
RIPK2	7748.0
ADAMTS18	7740.0
AOPEP	7726.0
MFGE8	7712.0
SOCS5	7711.0
ZBED1	7700.0
GALNT1	7647.0
B4GALT6	7608.0
EEF2KMT	7605.0
ALPL	7598.0
DYNC1I1	7586.0
THSD7A	7583.0
SPRN	7535.0
SPSB4	7511.0
GCNT3	7502.0
PIGP	7487.0
TGFBR2	7472.0
FEM1C	7458.0
BCL10	7455.0
HLA-B	7436.0
HRC	7430.0
TMED7	7412.0
ADAM10	7409.0
SPSB1	7391.0
KIFC3	7370.0
IGFBP6	7365.0
PSMB5	7356.0
CHST10	7341.0
B4GALT2	7320.0
CCDC8	7319.0
RAB23	7304.0
LMAN1	7288.0
H2BC18	7287.0
KLHL3	7286.0
CNTN5	7281.0
ADAMTS2	7210.0
FUOM	7178.0
ALG11	7163.0
PIGK	7162.0
KLHL13	7157.0
USP18	7149.0
GFPT1	7117.0
PEX13	7086.0
RAB13	7081.0
CSF1	7069.0
ARSB	7047.0
LARGE1	7016.0
ITM2B	6999.0
ADAMTS14	6991.0
PLA2G7	6979.0
VDAC1	6972.0
ADAMTS5	6932.0
OTUD7B	6913.0
FBXO17	6877.0
KLK1	6876.0
RPS27L	6864.0
EID3	6861.0
MTRF1L	6846.0
SRPRB	6824.0
COMMD2	6812.0
CD59	6807.0
SEC31A	6800.0
NR3C2	6784.0
GALNT9	6772.0
GSPT2	6768.0
VCAN	6763.0
UAP1	6747.0
OTUB2	6719.0
GNG11	6712.0
SMC5	6705.0
SMAD7	6681.0
RAB42	6669.0
KLHL25	6656.0
FBXL7	6637.0
DCUN1D5	6598.0
MCFD2	6591.0
DPH5	6568.0
UBE2D1	6535.0
MRPS6	6533.0
EXOC2	6525.0
B3GNT3	6524.0
COMMD5	6509.0
SSR3	6502.0
KLHL20	6494.0
TUBB3	6485.0
KLK2	6469.0
RPL41	6462.0
RGS9	6460.0
ADAMTSL1	6435.0
B3GNT9	6430.0
NUS1	6404.0
TULP4	6376.0
PIGA	6371.0
POLB	6349.0
USO1	6347.0
FBXW12	6337.0
FBXO32	6336.0
PCGF2	6331.0
GMDS	6327.0
ADAMTS10	6326.0
RAB15	6301.0
ST6GALNAC2	6299.0
THSD4	6284.0
SEM1	6281.0
SNCAIP	6279.0
STC2	6264.0
VASH1	6262.0
LRRC49	6261.0
DYNLL1	6259.0
PIGF	6238.0
ST8SIA1	6235.0
FBXW11	6219.0
TP53BP1	6204.0
COPB1	6189.0
NR3C1	6171.0
EEF1G	6165.0
MXRA8	6149.0
RNF7	6109.0
TNFAIP3	6107.0
GNG10	6094.0
RRAGA	6093.0
SOCS6	6090.0
RPS2	6089.0
EEF1A1P5	6039.0
RPS9	6020.0
GALNT2	6012.0
RAB27B	6009.0
TF	6008.0
TFG	5995.0
NAPG	5992.0
UCHL3	5983.0
RTN4RL1	5969.0
BACE1	5927.0
RPL18A	5926.0
DDX5	5910.0
EIF4A1	5895.0
TMED10	5891.0
HSPA8	5871.0
EEF1A1	5862.0
IGF2	5853.0
TRAPPC4	5852.0
EPAS1	5851.0
DDX58	5850.0
DNAJC24	5844.0
STAM2	5822.0
FBXL22	5794.0
BIRC2	5787.0
RAB1A	5784.0
WSB2	5770.0
ATP6AP2	5760.0
RPS13	5739.0
VDAC2	5727.0
RPLP0	5695.0
RPL24	5693.0
H2BC4	5688.0
B3GALNT2	5680.0
RAB2A	5669.0
IGFBP5	5668.0
H2BC5	5661.0
SMAD3	5657.0
DPH3	5654.0
RPL39L	5631.0
ELOB	5627.0
CHM	5613.0
GALNT14	5588.0
SSR1	5583.0
LTBP1	5569.0
TOMM20	5559.0
EDEM3	5543.0
GALNT7	5536.0
MRPL40	5533.0
SSR2	5527.0
ADAMTSL2	5516.0
TOPORS	5512.0
RPS3A	5482.0
KIN	5479.0
CAND1	5473.0
RAB20	5455.0
PFDN4	5434.0
COG5	5428.0
B4GALT1	5424.0
RPL36A	5419.0
TCF7L2	5418.0
ADGRF5	5405.0
EEF2	5402.0
CUL4B	5401.0
CSNK2A2	5397.0
IFIH1	5391.0
FUCA1	5384.0
NSMCE1	5382.0
RAB5A	5379.0
RPL7	5370.0
RPL37A	5366.0
NEU1	5362.0
SEC61G	5359.0
MRPL24	5355.0
DCTN6	5354.0
ALG2	5350.0
RPL23A	5347.0
SELENOS	5328.0
MRPL15	5326.0
PHC1	5297.0
UBE2A	5294.0
MRPL42	5261.0
MYC	5260.0
MIA2	5242.0
THRB	5230.0
MRPL33	5226.0
RPL13A	5213.0
EIF3I	5192.0
RPL13	5185.0
RPS16	5179.0
KIF5B	5157.0
RPL15	5149.0
NPM1	5146.0
SHPRH	5144.0
EIF2S1	5134.0
GNG2	5131.0
IARS1	5118.0
RARS1	5107.0
COPS2	5096.0
MRPS33	5094.0
RELA	5093.0
RPL4	5091.0
MRPL30	5090.0
UBE2Z	5089.0
PSME2	5088.0
B3GLCT	5086.0
MRPL54	5080.0
DERL1	5065.0
TRIM4	5056.0
EXOC5	5051.0
RPL36AL	5042.0
LMCD1	5016.0
RAB14	5009.0
APP	5003.0
RPS11	4999.0
HSPG2	4982.0
PARK7	4976.0
SPTBN5	4973.0
RPS19	4946.0
ASXL2	4936.0
GNE	4909.0
PLG	4900.0
POMGNT1	4896.0
RPL32	4893.0
TNIP2	4879.0
RPL39	4878.0
MRPL51	4868.0
TBCE	4867.0
XRN2	4865.0
HIC1	4836.0
NEURL2	4835.0
RPL29	4831.0
ST3GAL5	4830.0
RPL31	4824.0
ST8SIA4	4814.0
RPS10	4796.0
DYNC1I2	4775.0
AGT	4741.0
FBXO22	4740.0
RPL19	4738.0
BMI1	4727.0
SUMF1	4717.0
TRAM1	4708.0
PFDN5	4704.0
COPS8	4684.0
FBN1	4682.0
MRPS35	4678.0
MAN1A2	4677.0
ELOC	4667.0
SLC30A5	4654.0
UBA6	4651.0
UBE2R2	4633.0
FKBP9	4621.0
GADD45GIP1	4617.0
PDCL	4604.0
UBE2E3	4572.0
MRPL14	4561.0
RAB29	4557.0
RPS27A	4555.0
RNF2	4554.0
FPGT	4550.0
TRAPPC3	4548.0
EIF1AX	4546.0
EEF1D	4542.0
RPL28	4540.0
SUMO1	4538.0
DAG1	4533.0
GNA11	4530.0
ETF1	4529.0
MRPL53	4523.0
RPL18	4499.0
MRPS36	4496.0
RAB33B	4490.0
RPL7A	4483.0
EEF1B2	4480.0
EXOC4	4475.0
KDELR1	4446.0
COPA	4434.0
SPTAN1	4430.0
RPL3	4426.0
TTLL1	4425.0
MBTPS1	4422.0
MRPS28	4408.0
EIF3E	4400.0
SEC16B	4395.0
THY1	4385.0
COPZ1	4357.0
MSRB2	4337.0
FBXL13	4329.0
PSMA2	4316.0
LGALS1	4297.0
ST3GAL1	4294.0
RPL17	4292.0
MBD5	4291.0
GALNT8	4279.0
RPS3	4276.0
RPL27	4270.0
LAMB2	4268.0
RPL23	4262.0
APOL1	4259.0
OTUD7A	4250.0
RPL6	4249.0
RPL35A	4246.0
TNKS	4242.0
ARSL	4241.0
RPS18	4239.0
LSAMP	4229.0
RAB18	4215.0
RPS23	4200.0
SOCS2	4196.0
RPL10A	4189.0
B4GAT1	4178.0
NUDT14	4173.0
RPS17	4171.0
UBE2N	4169.0
GOSR1	4167.0
RPS5	4154.0
EIF3L	4150.0
RPL12	4132.0
RPS8	4115.0
SPHK1	4113.0
RECK	4108.0
RANBP2	4107.0
USP37	4100.0
SRP9	4066.0
SIAH1	4064.0
PTEN	4060.0
ATXN3	4059.0
MRPL27	4056.0
LARS1	4043.0
RAB4A	4039.0
TAF9B	4020.0
STAG2	4003.0
RPL8	4000.0
TFPT	3990.0
H2AC6	3982.0
DAD1	3972.0
ACE	3971.0
PSENEN	3970.0
PTRH2	3967.0
MTFMT	3962.0
RPL14	3947.0
NUP35	3944.0
RPS24	3930.0
RPL34	3928.0
SLC17A5	3923.0
SMAD1	3920.0
JOSD2	3919.0
TTLL11	3914.0
TUBB6	3913.0
PGR	3912.0
THSD1	3897.0
IGFBP2	3895.0
FBXO30	3892.0
SARS1	3890.0
RPL37	3888.0
RPS25	3886.0
RORA	3885.0
RPS7	3878.0
SEC11A	3858.0
ARFGEF2	3856.0
ARFGAP3	3842.0
COPS4	3834.0
RAB21	3829.0
YKT6	3827.0
FOLR2	3823.0
RPL26	3817.0
TMED2	3813.0
NAGK	3808.0
ASGR1	3795.0
FSTL1	3781.0
USP42	3779.0
SEC13	3773.0
NUB1	3753.0
RAB7B	3749.0
RAB11A	3742.0
RPL35	3741.0
TOP2B	3740.0
COPS6	3739.0
UBE2E1	3718.0
RPS12	3713.0
ANKRD28	3697.0
RPS15A	3668.0
FBXL3	3653.0
F5	3647.0
RAB7A	3642.0
RPL10	3638.0
USP2	3633.0
SENP5	3631.0
SEC24A	3611.0
SRP14	3598.0
PIAS3	3586.0
ICMT	3582.0
COMMD10	3580.0
B3GNT7	3575.0
SLC30A7	3572.0
FBXO21	3568.0
RPL38	3564.0
EIF3G	3561.0
LONP2	3539.0
MRPS18A	3531.0
PSMD10	3520.0
RPL36	3513.0
KLHL11	3493.0
BTBD1	3484.0
GAN	3479.0
TTLL7	3477.0
RPS6	3469.0
RPS21	3461.0
USP11	3450.0
PSMA5	3448.0
EARS2	3422.0
RPL30	3402.0
RPS15	3394.0
EIF2B2	3359.0
CETN2	3356.0
UBE2W	3354.0
EIF5A2	3344.0
FBXO44	3332.0
OBSL1	3331.0
EIF3H	3328.0
EIF2B3	3316.0
DCAF13	3312.0
FAU	3307.0
MRPL47	3300.0
LAMC1	3285.0
RPL22	3284.0
SRP72	3272.0
ADRA2C	3268.0
BMP4	3258.0
PDIA3	3249.0
GNG12	3240.0
MRPS24	3238.0
KIF5C	3214.0
RPL21	3212.0
ARRB1	3206.0
CHML	3204.0
PEX10	3180.0
IARS2	3179.0
RPS29	3177.0
TMED9	3175.0
GFM1	3172.0
UBE2B	3166.0
NSMCE3	3156.0
CTSC	3154.0
SEC23IP	3137.0
TNKS2	3134.0
DCAF10	3121.0
B3GNT2	3117.0
ACTR10	3096.0
LYPD3	3090.0
ALG10B	3086.0
TPGS2	3083.0
RARA	3069.0
MRPL19	3066.0
SLC35C1	3065.0
RPL5	3062.0
RPL22L1	3056.0
PSMA3	3043.0
KIF13A	3036.0
RPS27	3034.0
GGCX	3020.0
DDX17	3015.0
TTLL5	3009.0
PCSK9	3006.0
POFUT2	3002.0
MRPS18C	3000.0
ABCA3	2995.0
GFM2	2992.0
CCT4	2966.0
MRPL48	2954.0
SUMO2	2951.0
PMM2	2950.0
ETFBKMT	2948.0
COPB2	2926.0
UBE2D3	2914.0
NLRP3	2913.0
ADAMTS7	2911.0
RPS20	2909.0
CCT3	2900.0
PPA1	2857.0
MRPL21	2853.0
EIF3J	2844.0
KLHL5	2830.0
C1GALT1C1	2799.0
H2BC11	2796.0
NRIP1	2792.0
EPRS1	2788.0
BET1	2785.0
RAB6A	2777.0
MRPL50	2773.0
TUBA8	2771.0
KLHL21	2747.0
STAT3	2744.0
UBE2V2	2741.0
MGAT2	2736.0
NSF	2734.0
COMMD6	2718.0
CBX8	2704.0
MGAT5	2696.0
RPLP1	2674.0
MDM2	2666.0
SEC22B	2660.0
ADAMTS12	2652.0
SPCS1	2646.0
CKAP4	2630.0
COMMD8	2629.0
SP3	2615.0
RPL27A	2608.0
BECN1	2607.0
UBXN7	2592.0
SEC61A1	2587.0
ADAMTS13	2575.0
UBC	2572.0
SRD5A3	2569.0
CAPZA2	2564.0
PEX2	2555.0
CUL5	2551.0
ADAMTSL3	2548.0
MYRIP	2527.0
MRPL3	2520.0
RPS4Y1	2516.0
CNIH3	2501.0
COMMD1	2492.0
PROS1	2480.0
RNF181	2476.0
USP28	2472.0
CCDC59	2471.0
LMAN2L	2467.0
FBXL18	2453.0
KLHL42	2443.0
STX5	2431.0
LAMB1	2429.0
MUC12	2420.0
DYNC1LI1	2403.0
EEF1E1	2384.0
CP	2377.0
USP25	2365.0
SHISA5	2350.0
EIF4A2	2349.0
UBE2L6	2336.0
INHBB	2331.0
SUZ12	2329.0
RAET1G	2325.0
JOSD1	2307.0
AURKAIP1	2304.0
GARS1	2291.0
AIMP1	2283.0
ZNF131	2274.0
CDC73	2260.0
USP22	2248.0
CHCHD1	2240.0
TBCB	2238.0
RAB12	2235.0
UBE2D2	2232.0
DNAJC3	2229.0
FUT8	2225.0
RAB8B	2214.0
PSMD8	2211.0
PSMD14	2194.0
PIAS2	2164.0
RNF139	2162.0
ALG13	2143.0
NUP133	2121.0
PSMA4	2112.0
MYO5A	2084.0
PRSS23	2072.0
SPSB2	2071.0
UBA3	2039.0
SPCS3	2037.0
KLHL9	2036.0
DARS1	2034.0
RHOA	2032.0
PIGH	2020.0
MAP3K7	2009.0
RPL11	2004.0
RAB22A	1992.0
B2M	1973.0
RPLP2	1969.0
NR1H3	1948.0
OS9	1939.0
STAMBP	1935.0
AP3M1	1927.0
CCT6A	1924.0
PSMB4	1921.0
MITF	1911.0
HDAC2	1907.0
PHC3	1906.0
SEL1L	1903.0
TOMM70	1895.0
FCGR3B	1888.0
MRPS7	1885.0
VNN2	1883.0
HNRNPC	1874.0
TUBB2A	1872.0
MLEC	1871.0
PSME3	1870.0
ST3GAL4	1859.0
FUCA2	1853.0
TGOLN2	1845.0
PSMD13	1835.0
DDB2	1833.0
NUP58	1820.0
MRPS21	1818.0
FBXW8	1807.0
KLHL2	1787.0
MUL1	1781.0
RPS28	1779.0
CUL7	1778.0
TXN	1776.0
EIF3K	1770.0
MRPL12	1762.0
CCT8	1748.0
DNMT3A	1741.0
APH1B	1738.0
FBXO27	1726.0
POMT2	1722.0
ERO1B	1691.0
H3-3A	1684.0
NUCB1	1675.0
FBXO31	1669.0
FBXO40	1664.0
EIF3M	1661.0
DCUN1D3	1647.0
MRPS23	1638.0
ESR1	1632.0
FEM1B	1609.0
EXOC8	1587.0
GALNT4	1583.0
MGAT1	1571.0
TDG	1565.0
USP8	1564.0
DCAF5	1561.0
PSME1	1537.0
UBE2G2	1534.0
EIF5	1532.0
SKP1	1522.0
DPH6	1517.0
RPL26L1	1510.0
DYNC1LI2	1502.0
MRPS12	1500.0
MIA3	1490.0
MRPL13	1485.0
CANX	1469.0
ALG14	1466.0
USP16	1460.0
PPA2	1459.0
CTSD	1442.0
MRPS10	1436.0
MANEA	1434.0
EIF3D	1419.0
IDE	1414.0
PFDN1	1398.0
ALG5	1365.0
APC	1359.0
WSB1	1357.0
NARS2	1351.0
EIF4E	1341.0
MTIF2	1335.0
SEC61B	1331.0
ATXN7	1330.0
PEX12	1320.0
GOLGB1	1295.0
SUMF2	1276.0
SP100	1267.0
RUVBL1	1258.0
CCT7	1246.0
ALG8	1237.0
RARS2	1230.0
RPS14	1220.0
NFKB2	1209.0
MRPS15	1208.0
RBBP5	1205.0
SEC22A	1198.0
TGFB1	1195.0
HLTF	1187.0
PAF1	1183.0
MUC1	1180.0
PUM2	1179.0
B4GALNT2	1166.0
DYNC1H1	1136.0
GALNT10	1127.0
SMAD4	1118.0
SUMO3	1104.0
MRPL34	1088.0
SAR1B	1080.0
KARS1	1073.0
CALB1	1061.0
SMURF2	1060.0
PRMT3	1045.0
XRCC4	1037.0
PIGB	1035.0
TTL	1032.0
GAS6	1029.0
COMMD3	1026.0
NCOA2	1018.0
ETFB	1006.0
OTOA	1003.0
EIF3C	985.0
USP12	971.0
GOSR2	943.0
MGAT4A	930.0
STX17	928.0
RNF185	910.0
TRAPPC5	907.0
FURIN	885.0
PSMA6	883.0
MRPL45	882.0
MAGT1	879.0
GNB3	853.0
PPARGC1A	851.0
QSOX1	792.0
TRAPPC6B	787.0
MRPL36	764.0
SRP19	755.0
UCN	754.0
DCUN1D4	731.0
ANO8	719.0
RAB40B	706.0
RAB5C	680.0
PIGT	655.0
SEC24B	641.0
DOLK	627.0
WDR48	622.0
EIF4B	607.0
SSPOP	569.0
PFDN2	554.0
PSMD1	535.0
DPM1	526.0
MRPL1	525.0
AMFR	522.0
CD52	508.0
CCT2	490.0
CHD3	479.0
CYLD	465.0
TBCA	460.0
H2AW	443.0
SCFD1	439.0
NANS	435.0
RGS11	432.0
RPN2	429.0
ARSK	404.0
DCUN1D1	403.0
DAP3	397.0
MRPS26	378.0
BIRC3	377.0
RIPK1	374.0
SLC30A6	368.0
EIF2S2	367.0
COMMD9	358.0
RAB35	353.0
APH1A	346.0
KLHL41	329.0
MVD	325.0
COPS7A	291.0
ST6GALNAC6	282.0
TRAPPC2L	271.0
ALG12	267.0
NTNG1	241.0
MRPS14	236.0
SENP8	223.0
MRPS22	216.0
ZDHHC2	213.0
ERCC8	202.0
SEC61A2	196.0
PDIA6	184.0
CALM1	172.0
GLB1	162.0
PIGN	149.0
MRPL39	148.0
STAG1	144.0
MRPL44	126.0
RPS4X	120.0
PEX14	90.0
BTRC	85.0
UBA52	75.0
RAB2B	71.0
PSMB7	43.0
NARS1	10.0
NUP88	1.0
UHRF2	-5.0
TRMT112	-6.0
EIF2S3	-13.0
RNF20	-17.0
DCTN4	-44.0
PSMB6	-57.0
FBXL5	-75.0
GORASP1	-139.0
UBE2K	-154.0
RAB43	-157.0
SENP1	-174.0
ARF3	-181.0
MAN1B1	-183.0
MRPS18B	-186.0
PSMC3	-201.0
PSMB9	-203.0
PIGY	-205.5
PAX6	-227.0
FEM1A	-243.0
CCT5	-248.0
BRCC3	-252.0
PSMB1	-262.0
USP47	-280.0
COPS5	-300.0
LARS2	-303.0
USP49	-304.0
OTULIN	-308.0
ALG9	-331.0
PSMD12	-334.0
RAB11B	-345.0
CTSZ	-366.0
NUP107	-374.0
IL33	-378.0
MRPS17	-384.0
SATB1	-399.0
ACTR1A	-418.0
USP9X	-419.0
ALG1	-420.0
TMEM115	-435.0
SAE1	-454.0
PSME4	-458.0
TCP1	-465.0
TRAPPC10	-469.0
MRPS34	-477.0
MRPL32	-482.0
PSMA1	-487.0
EIF3A	-495.0
MRPL9	-501.0
SNX3	-504.0
MRPS31	-506.0
MYSM1	-507.0
FARS2	-511.0
CSNK2A1	-520.0
RABGGTB	-535.0
KCTD7	-578.0
FOXK2	-589.0
MAT2B	-595.0
TARS1	-617.0
GOLGA2	-705.0
APLP2	-712.0
PSMC6	-713.0
PSMD5	-770.0
KTN1	-777.0
RAB10	-781.0
CAPZA1	-798.0
CCP110	-805.0
MRPL18	-835.0
FBXW7	-853.0
COPG1	-862.0
TRAF3	-919.0
YARS2	-934.0
MRPL22	-943.0
UBE2S	-944.0
FBXO6	-959.0
FBXL4	-962.0
TRIM25	-975.0
ASB4	-977.0
MAN2A1	-998.0
EIF4H	-1018.0
MRPL57	-1043.0
TNIP3	-1050.0
MTIF3	-1051.0
MRPL35	-1069.0
PIGC	-1100.0
VBP1	-1113.0
FBXO11	-1168.0
RAD18	-1170.0
CUL2	-1189.0
CTR9	-1209.0
ASXL1	-1211.0
XPC	-1214.0
MPI	-1219.0
FBXL19	-1221.0
UBE2L3	-1224.0
GANAB	-1234.0
PSMB8	-1241.0
RTF1	-1248.0
MRPL43	-1249.0
H2BC21	-1250.0
NICN1	-1259.0
WDR61	-1272.0
DCAF7	-1278.0
CUL3	-1291.0
MRPL52	-1298.0
RNF103	-1301.0
INO80C	-1304.0
GPIHBP1	-1335.0
TRAPPC2	-1349.0
HERC2	-1369.0
COG4	-1370.0
TRRAP	-1395.0
EIF5A	-1406.0
ST3GAL6	-1407.0
KLHL22	-1418.0
SEH1L	-1420.0
UBA1	-1430.0
SERPINA10	-1431.0
DERL2	-1432.0
LRRC41	-1436.0
N6AMT1	-1444.0
RPL3L	-1445.0
GALNT11	-1449.0
DHDDS	-1454.0
TBCD	-1474.0
SUDS3	-1477.0
DDA1	-1504.0
TRIM13	-1517.0
GALNT6	-1523.0
SMAD2	-1532.0
NR1H2	-1545.0
PPARA	-1551.0
CUL1	-1579.0
DCTN1	-1587.0
MSRB3	-1592.0
RAB32	-1596.0
PML	-1609.0
EXOC6	-1618.0
CBX5	-1623.0
NFRKB	-1629.0
DCAF17	-1634.0
UCHL5	-1640.0
STT3A	-1656.0
MRPL58	-1662.0
SPTBN4	-1668.0
GSPT1	-1686.0
SRP54	-1688.0
ST6GALNAC3	-1706.0
COMMD7	-1736.0
CBX4	-1763.0
MRPL46	-1768.0
RAB31	-1772.0
SCMH1	-1774.0
NEDD8	-1797.0
USP33	-1799.0
CBX2	-1812.0
USP44	-1837.0
UBA2	-1838.0
SVBP	-1846.0
FBXO10	-1874.0
MDGA1	-1882.0
PCMT1	-1889.0
QARS1	-1918.0
RHOT1	-1919.0
RAB1B	-1935.0
OGT	-1950.0
GNB2	-1970.0
COPS3	-1998.0
VNN3	-2003.0
TADA3	-2004.0
BTBD6	-2006.0
PIAS4	-2032.0
PSMC2	-2035.0
NUP205	-2044.0
MRPL20	-2046.0
ST3GAL2	-2049.0
WARS2	-2074.0
COG8	-2075.0
THBS2	-2085.0
FBXL12	-2105.0
SLC35A1	-2112.0
TRAPPC9	-2128.0
RAB8A	-2157.0
ANPEP	-2164.0
WRN	-2194.0
MRPS16	-2195.0
SPCS2	-2196.0
GNAQ	-2199.0
METTL21A	-2214.0
RTN4RL2	-2217.0
FBXO15	-2229.0
ARFGAP1	-2238.0
GNB1	-2252.0
ACTL6A	-2253.0
VCP	-2260.0
ARF5	-2264.0
H2AZ1	-2265.0
VAMP2	-2279.0
TUFM	-2280.0
NUP153	-2287.0
INO80	-2298.0
RAD23B	-2304.0
YARS1	-2305.0
USP14	-2315.0
MRPL49	-2334.0
ARF1	-2335.0
DHPS	-2346.0
PSMB10	-2349.0
PSMC1	-2353.0
PSMB3	-2369.0
RPN1	-2375.0
CUL9	-2378.0
PEX5	-2380.0
NANP	-2390.0
ST8SIA5	-2398.0
NUP54	-2399.0
BET1L	-2424.0
PRKDC	-2432.0
RING1	-2436.0
EDEM1	-2440.0
NOP58	-2458.0
TBC1D20	-2474.0
NDC1	-2483.0
CARS1	-2487.0
DPH1	-2489.0
NCOR2	-2498.0
NRN1L	-2500.0
PSMD6	-2501.0
RAD21	-2511.0
SMC6	-2520.0
RBX1	-2533.0
H2BC12	-2546.0
SRP68	-2552.0
MRPS30	-2560.0
KAT2A	-2565.0
PIGL	-2566.0
FCSK	-2571.0
NSMCE2	-2577.0
SEC16A	-2578.0
EXOC1	-2609.0
MUC6	-2615.0
PSMA7	-2633.0
CAPZB	-2647.0
ARSD	-2649.0
UBE2G1	-2650.0
IGFBP4	-2653.0
UBB	-2665.0
MRPL23	-2669.0
ASB3	-2670.0
NUP160	-2679.0
MRPL41	-2685.0
EIF3F	-2691.0
PIGZ	-2721.0
ALG10	-2722.0
GNG5	-2767.0
FOXK1	-2772.0
DPM3	-2789.0
KDM1B	-2798.0
TPGS1	-2805.0
LY6K	-2813.0
CASP8AP2	-2846.0
NAE1	-2866.0
EIF2B4	-2867.0
HSP90B1	-2892.0
UCHL1	-2899.0
COG3	-2901.0
MDM4	-2906.0
SMC1A	-2919.0
CSNK1D	-2925.0
HNRNPK	-2935.0
UBE2F	-2937.0
AGBL3	-2961.0
MRPS2	-2982.0
NEU3	-2989.0
TTLL3	-3000.0
NUP155	-3011.0
EIF5B	-3017.0
RXRA	-3018.0
DAXX	-3032.0
MMP2	-3039.0
AIMP2	-3046.0
ACTR8	-3057.0
TOP2A	-3058.0
ALG6	-3063.0
UBE2J2	-3071.0
DCTN5	-3107.0
PIGV	-3111.0
MTA1	-3119.0
NAPB	-3152.0
INO80D	-3169.0
SENP2	-3183.0
C4A	-3187.0
KBTBD8	-3189.0
NR5A2	-3205.0
DCAF6	-3211.0
GATA6	-3224.0
PPP6R3	-3226.0
MRPS27	-3229.0
MRPS11	-3232.0
RNF168	-3236.0
RNF146	-3239.0
NPL	-3260.0
MARS2	-3263.0
AARS1	-3265.0
ASB7	-3269.0
RAB4B	-3275.0
LRR1	-3285.0
SPTBN1	-3307.0
PPP6C	-3313.0
VDAC3	-3338.0
USP34	-3340.0
WAC	-3343.0
C1GALT1	-3349.0
SSR4	-3359.0
POMT1	-3362.0
YY1	-3364.0
CDKN2A	-3397.0
H2AC11	-3404.0
WDR20	-3438.0
EP300	-3453.0
PSMD4	-3492.0
TRIM27	-3499.0
ADRM1	-3502.0
TOP1	-3515.0
USP15	-3542.0
GBF1	-3544.0
FBXW9	-3591.0
SIN3A	-3595.0
TAB1	-3608.0
ALG3	-3616.0
POM121C	-3641.0
PIGX	-3720.0
NUP50	-3737.0
UBXN1	-3741.0
PSMB2	-3751.0
TTLL10	-3758.0
MCRS1	-3763.0
PIGG	-3775.0
RAB27A	-3777.0
TRAPPC6A	-3780.0
AR	-3789.0
NUP98	-3797.0
DCAF8	-3846.0
DPH2	-3848.0
H2BC15	-3870.0
DCTN2	-3876.0
HDAC7	-3881.0
RCE1	-3893.0
RAB3B	-3914.0
VCPIP1	-3930.0
EIF4G1	-3934.0
PIAS1	-3955.0
ERO1A	-3966.0
TUBA1C	-3969.0
ASB13	-3980.0
KBTBD6	-3984.0
DCTN3	-3989.0
DDB1	-3995.0
NUP37	-3999.0
UBE2H	-4001.0
ASGR2	-4012.0
UBE2I	-4049.0
FBXO4	-4077.0
MRPL11	-4102.0
HLA-A	-4124.0
NOD1	-4138.0
UBE2M	-4139.0
ADAMTS3	-4140.0
CSNK2B	-4147.0
DARS2	-4158.0
KIF5A	-4174.0
YOD1	-4192.0
FBXL8	-4211.0
MARCHF6	-4215.0
SORL1	-4219.0
RNF135	-4257.0
TBCC	-4258.0
DNMT3B	-4263.0
P4HB	-4269.0
DYNLL2	-4285.0
CALR	-4286.0
FBXL14	-4294.0
USP5	-4315.0
OTUB1	-4377.0
METTL22	-4399.0
ZBTB16	-4408.0
FARSB	-4412.0
NUP62	-4426.0
COG7	-4441.0
NEGR1	-4449.0
TMEM129	-4450.0
RAD52	-4451.0
DDOST	-4482.0
BRCA1	-4538.0
GGA1	-4548.0
MARS1	-4552.0
RAB9B	-4556.0
RAB39A	-4560.0
NAPA	-4562.0
TTLL4	-4573.0
AGBL5	-4589.0
CCT6B	-4615.0
MRPL55	-4625.0
STS	-4632.0
ASB9	-4637.0
TTF1	-4642.0
HDAC1	-4644.0
EXOC7	-4646.0
ASB2	-4649.0
PSMC5	-4664.0
SRPRA	-4669.0
HARS2	-4692.0
RAB9A	-4704.0
PRKCSH	-4725.0
MAVS	-4726.0
ADAMTSL4	-4735.0
GNA15	-4736.0
PTP4A2	-4746.0
DPAGT1	-4758.0
KEAP1	-4787.0
RAB24	-4791.0
NR2C1	-4801.0
FBXL20	-4810.0
ZRANB1	-4832.0
HARS1	-4838.0
SKIV2L	-4851.0
KAT2B	-4874.0
CDK1	-4876.0
LMAN2	-4895.0
TSFM	-4918.0
FBXW5	-4950.0
WFS1	-4951.0
COG1	-4956.0
FSTL3	-4983.0
PIGM	-4984.0
ING2	-5003.0
GFPT2	-5010.0
PARP1	-5015.0
VHL	-5034.0
BST1	-5042.0
MME	-5052.0
PSMD7	-5071.0
TNIP1	-5095.0
ST3GAL3	-5106.0
FBXO7	-5124.0
COG2	-5131.0
TRIM28	-5139.0
SMC3	-5155.0
POMK	-5157.0
PABPC1	-5187.0
FBXW2	-5193.0
DCAF4	-5197.0
ADORA2A	-5203.0
NGLY1	-5204.0
MSRB1	-5247.0
B4GALT3	-5255.0
GMPPA	-5263.0
ST6GAL1	-5291.0
PFDN6	-5302.0
RENBP	-5305.0
VCPKMT	-5306.0
SNCA	-5315.0
TRAF2	-5316.0
RWDD3	-5319.0
PTCD3	-5340.0
POMC	-5345.0
B3GNT4	-5362.0
MEN1	-5385.0
NUP188	-5399.0
RPS26	-5402.0
SEC24C	-5410.0
EIF2B1	-5419.0
COPE	-5423.0
SAFB	-5431.0
TSPAN5	-5442.0
CREBBP	-5451.0
MRPS9	-5458.0
HIPK2	-5466.0
AARS2	-5507.0
TRAF6	-5526.0
PSMD2	-5529.0
USP3	-5563.0
RNF5	-5565.0
MDC1	-5566.0
ART4	-5626.0
L3MBTL2	-5632.0
WDR5	-5637.0
MRPS25	-5642.0
VARS1	-5665.0
FBXO41	-5683.0
PSMD3	-5686.0
NCOA1	-5688.0
RBBP7	-5724.0
GPS1	-5744.0
CISH	-5770.0
RAE1	-5771.0
AGBL2	-5778.0
AGTPBP1	-5781.0
MRPS5	-5784.0
USP48	-5788.0
MRPL4	-5789.0
B4GALT4	-5809.0
GPAA1	-5825.0
HDAC3	-5834.0
ERAL1	-5843.0
ARL2	-5844.0
THRA	-5853.0
TUBB4B	-5873.0
RNF40	-5876.0
CAMKMT	-5885.0
NUP43	-5897.0
TPR	-5915.0
USP24	-5919.0
PSMD11	-5926.0
FKBP8	-5929.0
WARS1	-5944.0
FFAR4	-6003.0
BARD1	-6014.0
EIF4EBP1	-6030.0
PSMF1	-6034.0
BIRC5	-6037.0
RFT1	-6057.0
UBD	-6059.0
PIGO	-6063.0
MRRF	-6072.0
FBXO9	-6077.0
TUBA1B	-6081.0
TAF10	-6109.0
MRPL37	-6122.0
SAA1	-6143.0
HCFC1	-6148.0
BLM	-6160.0
LEO1	-6179.0
RAB40A	-6192.0
AXIN1	-6195.0
CTSA	-6208.0
EDEM2	-6211.0
USP10	-6257.0
HGS	-6259.0
POM121	-6266.0
MRPL16	-6306.0
MRPL10	-6310.0
NUP214	-6384.0
UGGT1	-6394.0
PSMD9	-6396.0
CCDC22	-6404.0
PPARG	-6410.0
MAN1C1	-6417.0
MRPL28	-6423.0
ASB1	-6439.0
INO80E	-6452.0
NUP42	-6458.0
LTF	-6467.0
DOHH	-6489.0
MBD1	-6491.0
NCSTN	-6510.0
USP19	-6513.0
SEC22C	-6527.0
GNB5	-6530.0
ASB8	-6535.0
CTBP1	-6595.0
TRAPPC1	-6610.0
NAPSA	-6619.0
ACTB	-6627.0
MGAT4B	-6639.0
HDAC4	-6643.0
TSPAN14	-6646.0
LYZ	-6676.0
ASB6	-6680.0
PPP6R1	-6681.0
INO80B	-6699.0
RAB30	-6703.0
TSPAN15	-6705.0
ST8SIA6	-6715.0
PHC2	-6718.0
COMMD4	-6729.0
RAB36	-6731.0
CCNA2	-6737.0
AMDHD2	-6767.0
GBA	-6774.0
WRAP53	-6796.0
B3GNT8	-6800.0
MRTFA	-6866.0
FBXL16	-6877.0
EIF3B	-6895.0
SKP2	-6928.0
RANGAP1	-6931.0
ZNF350	-6940.0
WDTC1	-6955.0
FARSA	-6960.0
TP53	-6976.0
CDC34	-6980.0
PSMC4	-6992.0
IKBKE	-7024.0
CSF2RB	-7034.0
KCTD6	-7045.0
EXOC3	-7064.0
ASB16	-7082.0
CMAS	-7087.0
TADA2B	-7092.0
ST6GAL2	-7100.0
HIF3A	-7141.0
RAB3D	-7143.0
PIGS	-7164.0
DCUN1D2	-7170.0
SPARCL1	-7183.0
CCNE2	-7189.0
PCNA	-7230.0
NOP56	-7236.0
USP4	-7244.0
VARS2	-7245.0
SPTA1	-7256.0
SARS2	-7278.0
SPTBN2	-7281.0
BAP1	-7288.0
ACE2	-7291.0
FBXL15	-7293.0
TARS2	-7311.0
RABGGTA	-7324.0
PARS2	-7373.0
VNN1	-7389.0
MRPL2	-7424.0
OXA1L	-7435.0
GGA2	-7437.0
RAB5B	-7439.0
BABAM1	-7480.0
ST6GALNAC4	-7489.0
PNPLA2	-7521.0
ARFGAP2	-7576.0
RAB40C	-7583.0
UBE2C	-7617.0
GPC3	-7623.0
NUP93	-7651.0
USP30	-7686.0
CCNA1	-7689.0
FBXW4	-7720.0
NFKBIA	-7730.0
CUL4A	-7740.0
USP7	-7742.0
COPS7B	-7780.0
POMGNT2	-7809.0
SIAH2	-7829.0
DTL	-7845.0
GCNT1	-7876.0
GGA3	-7913.0
TUBB2B	-7932.0
MOGS	-7949.0
MSRA	-7960.0
AURKA	-7985.0
MGAT4C	-7993.0
APEH	-8010.0
EIF2B5	-8026.0
STAMBPL1	-8039.0
GNG7	-8041.0
DOLPP1	-8049.0
DPH7	-8060.0
RPA1	-8065.0
GFUS	-8098.0
ASB14	-8107.0
B4GALT5	-8126.0
ARSA	-8129.0
AMTN	-8187.0
ANKRD9	-8192.0
RNF144A	-8233.0
TECTA	-8245.0
IKBKG	-8285.0
MAN1A1	-8290.0
NSMCE4A	-8325.0
ANK1	-8328.0
ANK2	-8329.0
LARGE2	-8338.0
CTSG	-8376.0
CFP	-8391.0
MPDU1	-8392.0
USP21	-8421.0
SPON2	-8423.0
PMM1	-8443.0
STAM	-8457.0
DCAF11	-8467.0
SPON1	-8469.0
CLSPN	-8477.0
ENGASE	-8485.0
DCAF16	-8490.0
SYVN1	-8491.0
ADAMTSL5	-8501.0
OTUD5	-8558.0
CTSH	-8581.0
F8	-8645.0
DNMT1	-8652.0
GMPPB	-8672.0
MBD6	-8701.0
ST6GALNAC1	-8710.0
SPSB3	-8715.0
OTUD3	-8741.0
TPST2	-8744.0
USP20	-8771.0
CARS2	-8790.0
MRPL38	-8808.0
AAAS	-8812.0
NUP85	-8821.0
TTLL12	-8839.0
DPM2	-8843.0
CDC20	-8856.0
SEC11C	-8869.0
ARRB2	-8930.0
H2BU1	-8956.0
RNF123	-8961.0
ACTR5	-8975.0
MMP1	-9020.0
NTNG2	-9038.0
GSN	-9062.0
ARSG	-9073.0
UBE2T	-9085.0
NUP210	-9091.0
H2BC9	-9109.0
SPTB	-9120.0
CCNF	-9133.0
GALNTL6	-9150.0
PREB	-9179.0
P2RY2	-9186.0
MGAT3	-9205.0
MUC19	-9206.0
RAB39B	-9220.0
KBTBD7	-9246.0
RAB33A	-9254.0
PIGU	-9265.0
NOD2	-9272.0
H2AC18	-9274.0
GHRL	-9304.0
CDC25A	-9316.0
FOXO4	-9317.0
PIGW	-9337.0
ADRB2	-9350.0
UIMC1	-9373.0
IGFBP1	-9401.0
B3GNTL1	-9441.0
RAD23A	-9465.0
FGF23	-9480.0
ADAMTS16	-9492.0
GZMH	-9528.0
TUBB1	-9553.0
CDCA8	-9629.0
CCNE1	-9640.0
RAB3C	-9663.0
GATA3	-9671.0
PIGQ	-9724.0
AURKB	-9728.0
FN3KRP	-9787.0
ADAMTS15	-9812.0
TSPAN33	-9814.0
RAB37	-9884.0
GPLD1	-9888.0
TUBA4A	-9905.0
INCENP	-9919.0
CPM	-9927.0
MAN2A2	-9967.0
COPG2	-9978.0
NTM	-9999.0
RAB44	-10068.0
PCSK2	-10087.0
GALNT12	-10135.0
NR1I2	-10162.0
ACHE	-10172.0
FN3K	-10194.0
H2AC20	-10202.0
RAB6B	-10432.0
BCHE	-10437.0
CPB1	-10485.0
ADORA2B	-10561.0
MUC4	-10575.0
LEP	-10602.0
RAB26	-10609.0
XPNPEP2	-10687.0
CES1	-10690.0
PENK	-10712.0
CSF2RA	-10780.0
IGF1	-10790.0
TUBAL3	-10839.0
RAB19	-10861.0
CHRDL1	-10883.0
RGS6	-10893.0
MUC20	-10913.0
PCSK1	-10914.0
C3	-10942.0
APOB	-10965.0
SCG2	-10981.0
PRSS21	-10982.0
PGA4	-10993.0

---

Viral mRNA Translation

Viral mRNA Translation

	1402
set	Viral mRNA Translation
setSize	88
pANOVA	4.88e-15
s.dist	0.483
p.adjustANOVA	2.44e-13

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPSA	7908
RPL9	7848
RPS27L	6864
RPL41	6462
RPS2	6089
RPS9	6020
RPL18A	5926
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
RPS3A	5482
RPL36A	5419
RPL7	5370
RPL37A	5366
RPL23A	5347
RPL13A	5213
RPL13	5185
RPS16	5179
RPL15	5149

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPSA	7908
RPL9	7848
RPS27L	6864
RPL41	6462
RPS2	6089
RPS9	6020
RPL18A	5926
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
RPS3A	5482
RPL36A	5419
RPL7	5370
RPL37A	5366
RPL23A	5347
RPL13A	5213
RPL13	5185
RPS16	5179
RPL15	5149
RPL4	5091
RPL36AL	5042
RPS11	4999
RPS19	4946
RPL32	4893
RPL39	4878
RPL29	4831
RPL31	4824
RPS10	4796
RPL19	4738
RPS27A	4555
RPL28	4540
RPL18	4499
RPL7A	4483
RPL3	4426
RPL17	4292
RPS3	4276
RPL27	4270
RPL23	4262
RPL6	4249
RPL35A	4246
RPS18	4239
RPS23	4200
RPL10A	4189
RPS17	4171
RPS5	4154
RPL12	4132
RPS8	4115
RPL8	4000
RPL14	3947
RPS24	3930
RPL34	3928
RPL37	3888
RPS25	3886
RPS7	3878
RPL26	3817
RPL35	3741
RPS12	3713
RPS15A	3668
RPL10	3638
RPL38	3564
RPL36	3513
RPS6	3469
RPS21	3461
RPL30	3402
RPS15	3394
FAU	3307
RPL22	3284
RPL21	3212
RPS29	3177
RPL5	3062
RPL22L1	3056
RPS27	3034
RPS20	2909
RPLP1	2674
RPL27A	2608
RPS4Y1	2516
DNAJC3	2229
RPL11	2004
RPLP2	1969
RPS28	1779
RPL26L1	1510
RPS14	1220
GRSF1	704
RPS4X	120
UBA52	75
RPL3L	-1445
RPS26	-5402

---

GTP hydrolysis and joining of the 60S ribosomal subunit

GTP hydrolysis and joining of the 60S ribosomal subunit

	455
set	GTP hydrolysis and joining of the 60S ribosomal subunit
setSize	111
pANOVA	6.02e-15
s.dist	0.429
p.adjustANOVA	2.91e-13

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPSA	7908
RPL9	7848
RPS27L	6864
RPL41	6462
RPS2	6089
RPS9	6020
RPL18A	5926
EIF4A1	5895
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
RPS3A	5482
RPL36A	5419
RPL7	5370
RPL37A	5366
RPL23A	5347
RPL13A	5213
EIF3I	5192
RPL13	5185

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPSA	7908
RPL9	7848
RPS27L	6864
RPL41	6462
RPS2	6089
RPS9	6020
RPL18A	5926
EIF4A1	5895
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
RPS3A	5482
RPL36A	5419
RPL7	5370
RPL37A	5366
RPL23A	5347
RPL13A	5213
EIF3I	5192
RPL13	5185
RPS16	5179
RPL15	5149
EIF2S1	5134
RPL4	5091
RPL36AL	5042
RPS11	4999
RPS19	4946
RPL32	4893
RPL39	4878
RPL29	4831
RPL31	4824
RPS10	4796
RPL19	4738
RPS27A	4555
EIF1AX	4546
RPL28	4540
RPL18	4499
RPL7A	4483
RPL3	4426
EIF3E	4400
RPL17	4292
RPS3	4276
RPL27	4270
RPL23	4262
RPL6	4249
RPL35A	4246
RPS18	4239
RPS23	4200
RPL10A	4189
RPS17	4171
RPS5	4154
EIF3L	4150
RPL12	4132
RPS8	4115
RPL8	4000
RPL14	3947
RPS24	3930
RPL34	3928
RPL37	3888
RPS25	3886
RPS7	3878
RPL26	3817
RPL35	3741
RPS12	3713
RPS15A	3668
RPL10	3638
RPL38	3564
EIF3G	3561
RPL36	3513
RPS6	3469
RPS21	3461
RPL30	3402
RPS15	3394
EIF3H	3328
FAU	3307
RPL22	3284
RPL21	3212
RPS29	3177
RPL5	3062
RPL22L1	3056
RPS27	3034
RPS20	2909
EIF3J	2844
RPLP1	2674
RPL27A	2608
RPS4Y1	2516
EIF4A2	2349
RPL11	2004
RPLP2	1969
RPS28	1779
EIF3K	1770
EIF3M	1661
EIF5	1532
RPL26L1	1510
EIF3D	1419
EIF4E	1341
RPS14	1220
EIF3C	985
EIF4B	607
EIF2S2	367
RPS4X	120
UBA52	75
EIF2S3	-13
EIF3A	-495
EIF4H	-1018
RPL3L	-1445
EIF3F	-2691
EIF5B	-3017
EIF4G1	-3934
RPS26	-5402
EIF3B	-6895

---

L13a-mediated translational silencing of Ceruloplasmin expression

L13a-mediated translational silencing of Ceruloplasmin expression

	614
set	L13a-mediated translational silencing of Ceruloplasmin expression
setSize	110
pANOVA	8.28e-15
s.dist	0.428
p.adjustANOVA	3.76e-13

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPSA	7908
RPL9	7848
RPS27L	6864
RPL41	6462
RPS2	6089
RPS9	6020
RPL18A	5926
EIF4A1	5895
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
RPS3A	5482
RPL36A	5419
RPL7	5370
RPL37A	5366
RPL23A	5347
RPL13A	5213
EIF3I	5192
RPL13	5185

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPSA	7908
RPL9	7848
RPS27L	6864
RPL41	6462
RPS2	6089
RPS9	6020
RPL18A	5926
EIF4A1	5895
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
RPS3A	5482
RPL36A	5419
RPL7	5370
RPL37A	5366
RPL23A	5347
RPL13A	5213
EIF3I	5192
RPL13	5185
RPS16	5179
RPL15	5149
EIF2S1	5134
RPL4	5091
RPL36AL	5042
RPS11	4999
RPS19	4946
RPL32	4893
RPL39	4878
RPL29	4831
RPL31	4824
RPS10	4796
RPL19	4738
RPS27A	4555
EIF1AX	4546
RPL28	4540
RPL18	4499
RPL7A	4483
RPL3	4426
EIF3E	4400
RPL17	4292
RPS3	4276
RPL27	4270
RPL23	4262
RPL6	4249
RPL35A	4246
RPS18	4239
RPS23	4200
RPL10A	4189
RPS17	4171
RPS5	4154
EIF3L	4150
RPL12	4132
RPS8	4115
RPL8	4000
RPL14	3947
RPS24	3930
RPL34	3928
RPL37	3888
RPS25	3886
RPS7	3878
RPL26	3817
RPL35	3741
RPS12	3713
RPS15A	3668
RPL10	3638
RPL38	3564
EIF3G	3561
RPL36	3513
RPS6	3469
RPS21	3461
RPL30	3402
RPS15	3394
EIF3H	3328
FAU	3307
RPL22	3284
RPL21	3212
RPS29	3177
RPL5	3062
RPL22L1	3056
RPS27	3034
RPS20	2909
EIF3J	2844
RPLP1	2674
RPL27A	2608
RPS4Y1	2516
EIF4A2	2349
RPL11	2004
RPLP2	1969
RPS28	1779
EIF3K	1770
EIF3M	1661
RPL26L1	1510
EIF3D	1419
EIF4E	1341
RPS14	1220
EIF3C	985
EIF4B	607
EIF2S2	367
RPS4X	120
UBA52	75
EIF2S3	-13
EIF3A	-495
EIF4H	-1018
RPL3L	-1445
EIF3F	-2691
EIF4G1	-3934
PABPC1	-5187
RPS26	-5402
EIF3B	-6895

---

Response of EIF2AK4 (GCN2) to amino acid deficiency

Response of EIF2AK4 (GCN2) to amino acid deficiency

	1068
set	Response of EIF2AK4 (GCN2) to amino acid deficiency
setSize	100
pANOVA	8.29e-15
s.dist	0.449
p.adjustANOVA	3.76e-13

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ATF3	9190
RPSA	7908
RPL9	7848
DDIT3	7501
CEBPB	6956
RPS27L	6864
RPL41	6462
RPS2	6089
RPS9	6020
RPL18A	5926
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
RPS3A	5482
RPL36A	5419
RPL7	5370
RPL37A	5366
RPL23A	5347
RPL13A	5213

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ATF3	9190
RPSA	7908
RPL9	7848
DDIT3	7501
CEBPB	6956
RPS27L	6864
RPL41	6462
RPS2	6089
RPS9	6020
RPL18A	5926
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
RPS3A	5482
RPL36A	5419
RPL7	5370
RPL37A	5366
RPL23A	5347
RPL13A	5213
RPL13	5185
RPS16	5179
RPL15	5149
EIF2S1	5134
RPL4	5091
RPL36AL	5042
RPS11	4999
RPS19	4946
RPL32	4893
RPL39	4878
RPL29	4831
RPL31	4824
RPS10	4796
RPL19	4738
RPS27A	4555
RPL28	4540
RPL18	4499
RPL7A	4483
RPL3	4426
RPL17	4292
RPS3	4276
RPL27	4270
RPL23	4262
RPL6	4249
RPL35A	4246
RPS18	4239
RPS23	4200
RPL10A	4189
RPS17	4171
RPS5	4154
RPL12	4132
RPS8	4115
RPL8	4000
RPL14	3947
RPS24	3930
RPL34	3928
RPL37	3888
RPS25	3886
RPS7	3878
RPL26	3817
RPL35	3741
RPS12	3713
RPS15A	3668
RPL10	3638
RPL38	3564
RPL36	3513
RPS6	3469
RPS21	3461
RPL30	3402
RPS15	3394
FAU	3307
RPL22	3284
RPL21	3212
RPS29	3177
RPL5	3062
RPL22L1	3056
RPS27	3034
RPS20	2909
RPLP1	2674
RPL27A	2608
RPS4Y1	2516
ATF2	2149
RPL11	2004
RPLP2	1969
RPS28	1779
RPL26L1	1510
ATF4	1465
RPS14	1220
EIF2S2	367
RPS4X	120
UBA52	75
EIF2S3	-13
GCN1	-39
EIF2AK4	-780
IMPACT	-1053
RPL3L	-1445
ASNS	-3194
CEBPG	-3429
RPS26	-5402
TRIB3	-7900

---

SRP-dependent cotranslational protein targeting to membrane

SRP-dependent cotranslational protein targeting to membrane

	1102
set	SRP-dependent cotranslational protein targeting to membrane
setSize	111
pANOVA	1e-14
s.dist	0.425
p.adjustANOVA	4.4e-13

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPSA	7908
RPL9	7848
RPS27L	6864
SRPRB	6824
SSR3	6502
RPL41	6462
RPS2	6089
RPS9	6020
RPL18A	5926
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
SSR1	5583
SSR2	5527
RPS3A	5482
RPL36A	5419
RPL7	5370
RPL37A	5366
SEC61G	5359

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPSA	7908
RPL9	7848
RPS27L	6864
SRPRB	6824
SSR3	6502
RPL41	6462
RPS2	6089
RPS9	6020
RPL18A	5926
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
SSR1	5583
SSR2	5527
RPS3A	5482
RPL36A	5419
RPL7	5370
RPL37A	5366
SEC61G	5359
RPL23A	5347
RPL13A	5213
RPL13	5185
RPS16	5179
RPL15	5149
RPL4	5091
RPL36AL	5042
RPS11	4999
RPS19	4946
RPL32	4893
RPL39	4878
RPL29	4831
RPL31	4824
RPS10	4796
RPL19	4738
TRAM1	4708
RPS27A	4555
RPL28	4540
RPL18	4499
RPL7A	4483
RPL3	4426
RPL17	4292
RPS3	4276
RPL27	4270
RPL23	4262
RPL6	4249
RPL35A	4246
RPS18	4239
RPS23	4200
RPL10A	4189
RPS17	4171
RPS5	4154
RPL12	4132
RPS8	4115
SRP9	4066
RPL8	4000
RPL14	3947
RPS24	3930
RPL34	3928
RPL37	3888
RPS25	3886
RPS7	3878
SEC11A	3858
RPL26	3817
RPL35	3741
RPS12	3713
RPS15A	3668
RPL10	3638
SRP14	3598
RPL38	3564
RPL36	3513
RPS6	3469
RPS21	3461
RPL30	3402
RPS15	3394
FAU	3307
RPL22	3284
SRP72	3272
RPL21	3212
RPS29	3177
RPL5	3062
RPL22L1	3056
RPS27	3034
RPS20	2909
RPLP1	2674
SPCS1	2646
RPL27A	2608
SEC61A1	2587
RPS4Y1	2516
SPCS3	2037
RPL11	2004
RPLP2	1969
RPS28	1779
RPL26L1	1510
SEC61B	1331
RPS14	1220
SRP19	755
RPN2	429
SEC61A2	196
RPS4X	120
UBA52	75
RPL3L	-1445
SRP54	-1688
SPCS2	-2196
RPN1	-2375
SRP68	-2552
SSR4	-3359
DDOST	-4482
SRPRA	-4669
RPS26	-5402
SEC11C	-8869

---

Selenocysteine synthesis

Selenocysteine synthesis

	1124
set	Selenocysteine synthesis
setSize	92
pANOVA	1.14e-14
s.dist	0.466
p.adjustANOVA	4.89e-13

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPSA	7908
RPL9	7848
RPS27L	6864
RPL41	6462
RPS2	6089
RPS9	6020
RPL18A	5926
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
RPS3A	5482
RPL36A	5419
RPL7	5370
RPL37A	5366
RPL23A	5347
RPL13A	5213
RPL13	5185
RPS16	5179
RPL15	5149

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPSA	7908
RPL9	7848
RPS27L	6864
RPL41	6462
RPS2	6089
RPS9	6020
RPL18A	5926
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
RPS3A	5482
RPL36A	5419
RPL7	5370
RPL37A	5366
RPL23A	5347
RPL13A	5213
RPL13	5185
RPS16	5179
RPL15	5149
RPL4	5091
RPL36AL	5042
RPS11	4999
RPS19	4946
RPL32	4893
RPL39	4878
RPL29	4831
RPL31	4824
RPS10	4796
RPL19	4738
RPS27A	4555
RPL28	4540
RPL18	4499
RPL7A	4483
RPL3	4426
RPL17	4292
RPS3	4276
RPL27	4270
RPL23	4262
RPL6	4249
RPL35A	4246
RPS18	4239
RPS23	4200
RPL10A	4189
RPS17	4171
RPS5	4154
RPL12	4132
RPS8	4115
RPL8	4000
RPL14	3947
RPS24	3930
RPL34	3928
SARS1	3890
RPL37	3888
RPS25	3886
RPS7	3878
RPL26	3817
RPL35	3741
RPS12	3713
RPS15A	3668
RPL10	3638
RPL38	3564
RPL36	3513
RPS6	3469
RPS21	3461
RPL30	3402
RPS15	3394
FAU	3307
RPL22	3284
RPL21	3212
RPS29	3177
RPL5	3062
RPL22L1	3056
RPS27	3034
RPS20	2909
PSTK	2675
RPLP1	2674
RPL27A	2608
RPS4Y1	2516
RPL11	2004
RPLP2	1969
RPS28	1779
RPL26L1	1510
SEPHS2	1450
RPS14	1220
RPS4X	120
UBA52	75
EEFSEC	-608
SEPSECS	-1119
RPL3L	-1445
SECISBP2	-3395
RPS26	-5402

---

Eukaryotic Translation Termination

Eukaryotic Translation Termination

	370
set	Eukaryotic Translation Termination
setSize	92
pANOVA	1.68e-14
s.dist	0.463
p.adjustANOVA	6.98e-13

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPSA	7908
RPL9	7848
RPS27L	6864
GSPT2	6768
RPL41	6462
RPS2	6089
RPS9	6020
RPL18A	5926
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
RPS3A	5482
RPL36A	5419
RPL7	5370
RPL37A	5366
RPL23A	5347
RPL13A	5213
RPL13	5185
RPS16	5179

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPSA	7908
RPL9	7848
RPS27L	6864
GSPT2	6768
RPL41	6462
RPS2	6089
RPS9	6020
RPL18A	5926
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
RPS3A	5482
RPL36A	5419
RPL7	5370
RPL37A	5366
RPL23A	5347
RPL13A	5213
RPL13	5185
RPS16	5179
RPL15	5149
RPL4	5091
RPL36AL	5042
RPS11	4999
RPS19	4946
RPL32	4893
RPL39	4878
RPL29	4831
RPL31	4824
RPS10	4796
RPL19	4738
RPS27A	4555
RPL28	4540
ETF1	4529
RPL18	4499
RPL7A	4483
RPL3	4426
RPL17	4292
RPS3	4276
RPL27	4270
RPL23	4262
RPL6	4249
RPL35A	4246
RPS18	4239
RPS23	4200
RPL10A	4189
RPS17	4171
RPS5	4154
RPL12	4132
RPS8	4115
RPL8	4000
RPL14	3947
RPS24	3930
RPL34	3928
RPL37	3888
RPS25	3886
RPS7	3878
RPL26	3817
RPL35	3741
RPS12	3713
RPS15A	3668
RPL10	3638
RPL38	3564
RPL36	3513
RPS6	3469
RPS21	3461
RPL30	3402
RPS15	3394
FAU	3307
RPL22	3284
RPL21	3212
RPS29	3177
RPL5	3062
RPL22L1	3056
RPS27	3034
RPS20	2909
RPLP1	2674
RPL27A	2608
RPS4Y1	2516
RPL11	2004
RPLP2	1969
RPS28	1779
RPL26L1	1510
RPS14	1220
RPS4X	120
UBA52	75
TRMT112	-6
N6AMT1	-1444
RPL3L	-1445
GSPT1	-1686
RPS26	-5402
APEH	-8010

---

Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

	772
set	Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
setSize	94
pANOVA	3.14e-14
s.dist	0.453
p.adjustANOVA	1.26e-12

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPSA	7908
RPL9	7848
RPS27L	6864
GSPT2	6768
RPL41	6462
RPS2	6089
RPS9	6020
RPL18A	5926
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
RPS3A	5482
RPL36A	5419
RPL7	5370
RPL37A	5366
RPL23A	5347
RPL13A	5213
RPL13	5185
RPS16	5179

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPSA	7908
RPL9	7848
RPS27L	6864
GSPT2	6768
RPL41	6462
RPS2	6089
RPS9	6020
RPL18A	5926
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
RPS3A	5482
RPL36A	5419
RPL7	5370
RPL37A	5366
RPL23A	5347
RPL13A	5213
RPL13	5185
RPS16	5179
RPL15	5149
RPL4	5091
RPL36AL	5042
RPS11	4999
RPS19	4946
RPL32	4893
RPL39	4878
RPL29	4831
RPL31	4824
RPS10	4796
RPL19	4738
RPS27A	4555
RPL28	4540
ETF1	4529
RPL18	4499
RPL7A	4483
RPL3	4426
RPL17	4292
RPS3	4276
RPL27	4270
RPL23	4262
RPL6	4249
RPL35A	4246
RPS18	4239
RPS23	4200
RPL10A	4189
RPS17	4171
RPS5	4154
RPL12	4132
RPS8	4115
RPL8	4000
RPL14	3947
RPS24	3930
RPL34	3928
RPL37	3888
RPS25	3886
RPS7	3878
RPL26	3817
RPL35	3741
RPS12	3713
RPS15A	3668
RPL10	3638
RPL38	3564
RPL36	3513
RPS6	3469
RPS21	3461
RPL30	3402
RPS15	3394
FAU	3307
RPL22	3284
RPL21	3212
RPS29	3177
RPL5	3062
RPL22L1	3056
RPS27	3034
RPS20	2909
RPLP1	2674
RPL27A	2608
RPS4Y1	2516
RPL11	2004
RPLP2	1969
NCBP1	1828
RPS28	1779
RPL26L1	1510
RPS14	1220
NCBP2	687
RPS4X	120
UBA52	75
RPL3L	-1445
GSPT1	-1686
EIF4G1	-3934
UPF1	-4559
PABPC1	-5187
RPS26	-5402

---

Cell surface interactions at the vascular wall

Cell surface interactions at the vascular wall

	167
set	Cell surface interactions at the vascular wall
setSize	187
pANOVA	3.48e-14
s.dist	-0.321
p.adjustANOVA	1.36e-12

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
APOB	-10965
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHA2	-10886
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
APOB	-10965
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHA2	-10886
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
IGKV2-28	-10803
IGLV10-54	-10795
IGLV2-18	-10793
IGKV5-2	-10765
IGLV5-45	-10764
IGLV1-40	-10748
IGLV1-44	-10737
IGLV3-25	-10735
GRB14	-10734
IGLV3-27	-10722
IGLC1	-10709
IGLV4-69	-10707
IGLV3-21	-10693
IGLV1-36	-10689
IGLV1-47	-10672
PF4V1	-10663
IGLV6-57	-10655
IGKV4-1	-10646
IGKV2-30	-10624
IGHV3-23	-10617
IGHV2-5	-10606
IGKV1-17	-10600
SIRPG	-10567
IGKV3-11	-10566
IGLV4-60	-10497
IGKV1-5	-10469
IGLV5-37	-10417
IGHV4-34	-10407
IGHV1-46	-10406
CD177	-10402
IGLV3-19	-10372
PF4	-10333
IGKV3-15	-10313
IGKV3-20	-10300
SELP	-10265
IGKV1D-39	-9965
IGKV1-12	-9925
IGHV3-11	-9849
L1CAM	-9726
IGHV1-2	-9703
IGHV3-48	-9695
GP6	-9686
IGHA1	-9638
ITGAL	-9631
IGHV2-70	-9600
LCK	-9505
IGKV1-16	-9486
SLC7A10	-9329
CD2	-9310
IGKV2D-40	-9270
PTPN6	-9253
IGKC	-9161
ATP1B2	-9145
IGHM	-9131
SPN	-9035
MMP1	-9020
IGHV4-59	-8996
JCHAIN	-8868
IGKV1D-16	-8851
DOK2	-8797
ITGAX	-8712
ITGAM	-8682
ITGB2	-8620
SLC7A7	-8526
IGHV4-39	-8439
CEACAM6	-8040
INPP5D	-7827
IGLC7	-7752
SELPLG	-7486
SLC7A5	-7434
F11R	-7282
SLC3A2	-7178
GYPB	-7144
SDC1	-6917
ANGPT1	-6849
CD244	-6748
BSG	-6620
CEACAM8	-6543
GRB2	-6402
PSG6	-6380
GYPC	-6234
OLR1	-5935
PSG2	-5747
CEACAM1	-5677
MERTK	-5616
SELL	-5160
CD47	-5129
PPIL2	-5096
CEACAM3	-4960
CD74	-4915
PIK3R2	-4348
EPCAM	-4041
CXADR	-3859
JAML	-3480
IGKV2D-28	-3452
SLC7A8	-3088
IGHV1-69	-2950
PICK1	-2755
ITGA4	-2658
GYPA	-2601
SIRPA	-1760
CD44	-1557
FCER1G	-1414
IGKV1-33	-1353
SOS1	-1232
LYN	-973
IGKV1-39	-666
SLC7A6	-496
CD48	79
SRC	116
CD99L2	608
PPIA	795
GAS6	1029
TSPAN7	1070
VPREB1	1144
TGFB1	1195
PIK3CB	1574
PROCR	1670
CAV1	1740
PTPN11	1777
ITGB3	1908
PIK3R1	1940
PLCG1	2063
CD58	2258
SLC16A3	2408
PROS1	2480
IGKV3D-20	2798
FYN	2820
SDC3	3221
VPREB3	3262
ANGPT4	3788
KRAS	3793
ITGA3	4507
SLC7A11	4596
ESAM	4779
PIK3CA	4947
TREM1	4953
IGLL1	4985
NRAS	5076
TNFRSF10A	5119
JAM2	5165
ITGA6	5281
HRAS	5288
GLG1	5390
ANGPT2	5490
ATP1B3	5684
SLC16A8	6178
PECAM1	6355
ITGB1	6439
JAM3	6988
SHC1	7085
TEK	7119
TNFRSF10B	7155
YES1	7207
GPC1	7465
SLC16A1	7775
ITGA5	8051
MIF	8293
CD84	8294
SDC4	8438
CD99	8627
SDC2	8628
THBD	8667
ITGAV	8674
FN1	8982
TNFRSF10D	9067
ATP1B1	9130
SELE	9197

---

Cap-dependent Translation Initiation

Cap-dependent Translation Initiation

	150
set	Cap-dependent Translation Initiation
setSize	118
pANOVA	2.16e-13
s.dist	0.391
p.adjustANOVA	8.05e-12

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPSA	7908
RPL9	7848
RPS27L	6864
RPL41	6462
RPS2	6089
RPS9	6020
RPL18A	5926
EIF4A1	5895
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
RPS3A	5482
RPL36A	5419
RPL7	5370
RPL37A	5366
RPL23A	5347
RPL13A	5213
EIF3I	5192
RPL13	5185

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPSA	7908
RPL9	7848
RPS27L	6864
RPL41	6462
RPS2	6089
RPS9	6020
RPL18A	5926
EIF4A1	5895
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
RPS3A	5482
RPL36A	5419
RPL7	5370
RPL37A	5366
RPL23A	5347
RPL13A	5213
EIF3I	5192
RPL13	5185
RPS16	5179
RPL15	5149
EIF2S1	5134
RPL4	5091
RPL36AL	5042
RPS11	4999
RPS19	4946
RPL32	4893
RPL39	4878
RPL29	4831
RPL31	4824
RPS10	4796
RPL19	4738
RPS27A	4555
EIF1AX	4546
RPL28	4540
RPL18	4499
RPL7A	4483
RPL3	4426
EIF3E	4400
RPL17	4292
RPS3	4276
RPL27	4270
RPL23	4262
RPL6	4249
RPL35A	4246
RPS18	4239
RPS23	4200
RPL10A	4189
RPS17	4171
RPS5	4154
EIF3L	4150
RPL12	4132
RPS8	4115
RPL8	4000
RPL14	3947
RPS24	3930
RPL34	3928
RPL37	3888
RPS25	3886
RPS7	3878
RPL26	3817
RPL35	3741
RPS12	3713
RPS15A	3668
RPL10	3638
RPL38	3564
EIF3G	3561
RPL36	3513
RPS6	3469
RPS21	3461
RPL30	3402
RPS15	3394
EIF2B2	3359
EIF3H	3328
EIF2B3	3316
FAU	3307
RPL22	3284
RPL21	3212
RPS29	3177
RPL5	3062
RPL22L1	3056
RPS27	3034
RPS20	2909
EIF3J	2844
RPLP1	2674
RPL27A	2608
RPS4Y1	2516
EIF4A2	2349
RPL11	2004
RPLP2	1969
RPS28	1779
EIF3K	1770
EIF3M	1661
EIF5	1532
RPL26L1	1510
EIF3D	1419
EIF4E	1341
RPS14	1220
EIF3C	985
EIF4B	607
EIF2S2	367
RPS4X	120
UBA52	75
EIF2S3	-13
EIF3A	-495
EIF4H	-1018
RPL3L	-1445
EIF3F	-2691
EIF2B4	-2867
EIF5B	-3017
EIF4G1	-3934
PABPC1	-5187
RPS26	-5402
EIF2B1	-5419
EIF4EBP1	-6030
EIF3B	-6895
EIF2B5	-8026

---

Eukaryotic Translation Initiation

Eukaryotic Translation Initiation

	369
set	Eukaryotic Translation Initiation
setSize	118
pANOVA	2.16e-13
s.dist	0.391
p.adjustANOVA	8.05e-12

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPSA	7908
RPL9	7848
RPS27L	6864
RPL41	6462
RPS2	6089
RPS9	6020
RPL18A	5926
EIF4A1	5895
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
RPS3A	5482
RPL36A	5419
RPL7	5370
RPL37A	5366
RPL23A	5347
RPL13A	5213
EIF3I	5192
RPL13	5185

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPSA	7908
RPL9	7848
RPS27L	6864
RPL41	6462
RPS2	6089
RPS9	6020
RPL18A	5926
EIF4A1	5895
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
RPS3A	5482
RPL36A	5419
RPL7	5370
RPL37A	5366
RPL23A	5347
RPL13A	5213
EIF3I	5192
RPL13	5185
RPS16	5179
RPL15	5149
EIF2S1	5134
RPL4	5091
RPL36AL	5042
RPS11	4999
RPS19	4946
RPL32	4893
RPL39	4878
RPL29	4831
RPL31	4824
RPS10	4796
RPL19	4738
RPS27A	4555
EIF1AX	4546
RPL28	4540
RPL18	4499
RPL7A	4483
RPL3	4426
EIF3E	4400
RPL17	4292
RPS3	4276
RPL27	4270
RPL23	4262
RPL6	4249
RPL35A	4246
RPS18	4239
RPS23	4200
RPL10A	4189
RPS17	4171
RPS5	4154
EIF3L	4150
RPL12	4132
RPS8	4115
RPL8	4000
RPL14	3947
RPS24	3930
RPL34	3928
RPL37	3888
RPS25	3886
RPS7	3878
RPL26	3817
RPL35	3741
RPS12	3713
RPS15A	3668
RPL10	3638
RPL38	3564
EIF3G	3561
RPL36	3513
RPS6	3469
RPS21	3461
RPL30	3402
RPS15	3394
EIF2B2	3359
EIF3H	3328
EIF2B3	3316
FAU	3307
RPL22	3284
RPL21	3212
RPS29	3177
RPL5	3062
RPL22L1	3056
RPS27	3034
RPS20	2909
EIF3J	2844
RPLP1	2674
RPL27A	2608
RPS4Y1	2516
EIF4A2	2349
RPL11	2004
RPLP2	1969
RPS28	1779
EIF3K	1770
EIF3M	1661
EIF5	1532
RPL26L1	1510
EIF3D	1419
EIF4E	1341
RPS14	1220
EIF3C	985
EIF4B	607
EIF2S2	367
RPS4X	120
UBA52	75
EIF2S3	-13
EIF3A	-495
EIF4H	-1018
RPL3L	-1445
EIF3F	-2691
EIF2B4	-2867
EIF5B	-3017
EIF4G1	-3934
PABPC1	-5187
RPS26	-5402
EIF2B1	-5419
EIF4EBP1	-6030
EIF3B	-6895
EIF2B5	-8026

---

Selenoamino acid metabolism

Selenoamino acid metabolism

	1123
set	Selenoamino acid metabolism
setSize	115
pANOVA	3.08e-13
s.dist	0.393
p.adjustANOVA	1.12e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PAPSS2	9127
NNMT	8510
RPSA	7908
RPL9	7848
PAPSS1	7175
RPS27L	6864
RPL41	6462
RPS2	6089
RPS9	6020
RPL18A	5926
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
CTH	5629
RPS3A	5482
RPL36A	5419
RPL7	5370
RPL37A	5366
RPL23A	5347

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PAPSS2	9127
NNMT	8510
RPSA	7908
RPL9	7848
PAPSS1	7175
RPS27L	6864
RPL41	6462
RPS2	6089
RPS9	6020
RPL18A	5926
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
CTH	5629
RPS3A	5482
RPL36A	5419
RPL7	5370
RPL37A	5366
RPL23A	5347
RPL13A	5213
RPL13	5185
RPS16	5179
RPL15	5149
IARS1	5118
RARS1	5107
RPL4	5091
RPL36AL	5042
RPS11	4999
RPS19	4946
RPL32	4893
RPL39	4878
RPL29	4831
RPL31	4824
RPS10	4796
RPL19	4738
RPS27A	4555
RPL28	4540
RPL18	4499
RPL7A	4483
RPL3	4426
RPL17	4292
RPS3	4276
RPL27	4270
RPL23	4262
RPL6	4249
RPL35A	4246
RPS18	4239
RPS23	4200
RPL10A	4189
RPS17	4171
RPS5	4154
RPL12	4132
RPS8	4115
LARS1	4043
RPL8	4000
RPL14	3947
RPS24	3930
RPL34	3928
SARS1	3890
RPL37	3888
RPS25	3886
RPS7	3878
RPL26	3817
RPL35	3741
RPS12	3713
RPS15A	3668
RPL10	3638
RPL38	3564
RPL36	3513
RPS6	3469
RPS21	3461
RPL30	3402
RPS15	3394
FAU	3307
RPL22	3284
RPL21	3212
RPS29	3177
RPL5	3062
RPL22L1	3056
RPS27	3034
RPS20	2909
EPRS1	2788
PSTK	2675
RPLP1	2674
RPL27A	2608
RPS4Y1	2516
EEF1E1	2384
AIMP1	2283
DARS1	2034
RPL11	2004
RPLP2	1969
RPS28	1779
AHCY	1625
RPL26L1	1510
SEPHS2	1450
RPS14	1220
KARS1	1073
RPS4X	120
UBA52	75
EEFSEC	-608
TXNRD1	-832
SEPSECS	-1119
RPL3L	-1445
QARS1	-1918
HNMT	-2526
AIMP2	-3046
SECISBP2	-3395
MARS1	-4552
SCLY	-4650
RPS26	-5402
GSR	-7966
INMT	-8242
GNMT	-9483
CBS	-10582

---

Cellular response to starvation

Cellular response to starvation

	176
set	Cellular response to starvation
setSize	151
pANOVA	1.17e-12
s.dist	0.335
p.adjustANOVA	4.13e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ATF3	9190
ATP6V0D2	9049
ATP6V1B2	8121
ATP6V1A	8071
RPSA	7908
RPL9	7848
ATP6V1B1	7822
FNIP2	7812
ATP6V1H	7533
DDIT3	7501
ATP6V1G1	7359
CEBPB	6956
RPS27L	6864
ATP6V0E1	6852
ATP6V1D	6815
ATP6V1C1	6756
ATP6V1E1	6572
RPL41	6462
ATP6V1F	6364
RRAGA	6093

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ATF3	9190
ATP6V0D2	9049
ATP6V1B2	8121
ATP6V1A	8071
RPSA	7908
RPL9	7848
ATP6V1B1	7822
FNIP2	7812
ATP6V1H	7533
DDIT3	7501
ATP6V1G1	7359
CEBPB	6956
RPS27L	6864
ATP6V0E1	6852
ATP6V1D	6815
ATP6V1C1	6756
ATP6V1E1	6572
RPL41	6462
ATP6V1F	6364
RRAGA	6093
RPS2	6089
RPS9	6020
SH3BP4	5989
BMT2	5948
RPL18A	5926
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
ATP6V1E2	5521
RPS3A	5482
RPL36A	5419
RPL7	5370
RPL37A	5366
RPL23A	5347
RPL13A	5213
RPL13	5185
RPS16	5179
RPL15	5149
EIF2S1	5134
RPL4	5091
RPL36AL	5042
RPS11	4999
RPS19	4946
RPL32	4893
RPL39	4878
RPL29	4831
RPL31	4824
RPS10	4796
RPL19	4738
RPS27A	4555
RPL28	4540
RPL18	4499
RPL7A	4483
RPL3	4426
RPL17	4292
RPS3	4276
RPL27	4270
RPL23	4262
RPL6	4249
RPL35A	4246
RPS18	4239
RPS23	4200
RPL10A	4189
RPS17	4171
RPS5	4154
RPL12	4132
RPS8	4115
RPL8	4000
RPL14	3947
RPS24	3930
RPL34	3928
RPL37	3888
RPS25	3886
RPS7	3878
RPL26	3817
SESN2	3775
SEC13	3773
RPL35	3741
RPS12	3713
RPS15A	3668
RPL10	3638
RPL38	3564
RPL36	3513
RPS6	3469
RPS21	3461
RPL30	3402
RPS15	3394
FAU	3307
RPL22	3284
RPL21	3212
RPS29	3177
RPL5	3062
RPL22L1	3056
ATP6V0B	3037
RPS27	3034
RPS20	2909
RPLP1	2674
RPL27A	2608
SLC38A9	2565
RPS4Y1	2516
RHEB	2463
ATP6V0C	2287
ATF2	2149
RPL11	2004
RPLP2	1969
RPS28	1779
RPL26L1	1510
ATF4	1465
RPS14	1220
EIF2S2	367
TCIRG1	127
RPS4X	120
LAMTOR2	96
LAMTOR3	84
UBA52	75
EIF2S3	-13
GCN1	-39
LAMTOR5	-90
RRAGD	-315
EIF2AK4	-780
IMPACT	-1053
SEH1L	-1420
RPL3L	-1445
ATP6V1C2	-1450
KPTN	-1840
RPTOR	-1976
RRAGB	-2094
LAMTOR4	-2851
FNIP1	-3085
ASNS	-3194
MTOR	-3231
CEBPG	-3429
ATP6V0D1	-3562
LAMTOR1	-4068
MIOS	-4069
RRAGC	-4309
SZT2	-4316
ATP6V1G2	-4759
RPS26	-5402
ATP6V0E2	-5437
ITFG2	-6448
WDR24	-6909
FLCN	-6974
NPRL3	-7123
TRIB3	-7900
WDR59	-7905
MLST8	-7970
DEPDC5	-8093
SESN1	-9780
NPRL2	-10539

---

Extracellular matrix organization

Extracellular matrix organization

	374
set	Extracellular matrix organization
setSize	264
pANOVA	2.04e-12
s.dist	0.251
p.adjustANOVA	7.04e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MMP12	9185
MMP13	9184
BMP2	9181
SERPINE1	9164
ADAMTS4	9158
GDF5	9150
ADAMTS9	9135
MMP16	9132
COLGALT2	9125
ADAMTS1	9123
SPP1	9117
CTSK	9116
PLOD2	9107
TGFB2	9072
P3H2	9059
P4HA1	9055
FMOD	9038
LOX	9005
HTRA1	8999
ADAM12	8987

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MMP12	9185
MMP13	9184
BMP2	9181
SERPINE1	9164
ADAMTS4	9158
GDF5	9150
ADAMTS9	9135
MMP16	9132
COLGALT2	9125
ADAMTS1	9123
SPP1	9117
CTSK	9116
PLOD2	9107
TGFB2	9072
P3H2	9059
P4HA1	9055
FMOD	9038
LOX	9005
HTRA1	8999
ADAM12	8987
FN1	8982
FGF2	8938
ITGA2	8913
LUM	8911
THBS1	8890
SPARC	8869
HAPLN1	8847
IBSP	8845
COMP	8816
COL8A1	8814
LOXL4	8786
LAMB3	8732
DCN	8730
COL1A2	8720
NCAM1	8711
COL24A1	8680
ITGAV	8674
TIMP1	8656
CMA1	8634
SDC2	8628
LRP4	8624
TNN	8578
COL15A1	8542
PRKCA	8540
COL13A1	8514
DMP1	8497
COL10A1	8495
COL5A2	8484
KDR	8459
SDC4	8438
MMP19	8418
COL1A1	8357
TNC	8278
SH3PXD2A	8247
LOXL2	8139
COL22A1	8105
ICAM1	8067
ITGA5	8051
ITGA10	8010
ITGB5	7994
COL5A1	7977
MATN3	7965
COL7A1	7946
DST	7934
PCOLCE2	7922
MMP15	7868
PDGFA	7782
A2M	7750
ADAMTS18	7740
TNR	7708
P4HA2	7562
CASK	7539
COL12A1	7519
SERPINH1	7496
BMP7	7414
ADAM10	7409
PCOLCE	7385
BGN	7243
COL4A1	7213
ADAMTS2	7210
P4HA3	7100
ADAMTS14	6991
JAM3	6988
ADAMTS5	6932
COL11A1	6905
MFAP3	6869
COL8A2	6830
LTBP3	6776
COL26A1	6764
VCAN	6763
P3H3	6702
PLOD1	6680
PDGFB	6622
KLK2	6469
ITGB1	6439
CRTAP	6413
PECAM1	6355
CAPN11	6311
ITGA11	6307
COL6A2	6270
EFEMP2	5964
COL25A1	5885
TRAPPC4	5852
PXDN	5829
NID1	5750
COL3A1	5610
LTBP1	5569
BMP1	5505
COL6A1	5449
ITGA6	5281
JAM2	5165
ITGA8	5164
DDR2	5092
ADAM17	5082
CD151	5023
HSPG2	4982
COL21A1	4924
PLG	4900
LAMC3	4797
FBN1	4682
NID2	4634
CTSB	4631
ITGA9	4558
DAG1	4533
ITGA3	4507
ITGA1	4457
CAPN7	4364
TPSAB1	4302
LAMB2	4268
PTPRS	4188
PPIB	4170
TGFB3	4127
ACAN	4057
COL6A3	4021
COL4A2	4008
COL9A3	3899
LOXL3	3759
LTBP2	3722
MMP14	3658
LAMA4	3629
LTBP4	3553
COL16A1	3490
DDR1	3436
TIMP2	3343
NTN4	3335
LAMC1	3285
BMP4	3258
SDC3	3221
MMP9	2968
P3H1	2838
COL27A1	2644
LAMB1	2429
ICAM2	2152
LAMC2	2016
ITGB3	1908
CAPN2	1811
CTSD	1442
COL2A1	1380
TGFB1	1195
MFAP1	1081
FURIN	885
LAMA5	732
SCUBE3	700
CAPN5	649
LAMA3	152
LOXL1	117
MMP24	-125
SCUBE1	-456
TLL1	-462
CAPNS1	-484
AGRN	-570
VCAM1	-613
PLOD3	-854
COL18A1	-867
CASP3	-894
COL19A1	-1186
CTSS	-1531
CD44	-1557
COL5A3	-1699
FBLN5	-1732
ITGB4	-1899
PLEC	-1984
ASPN	-1995
COL17A1	-2174
CTSV	-2411
ITGA4	-2658
MMP11	-2845
MMP2	-3039
CTSL	-3062
ITGAD	-3104
COLGALT1	-3268
PSEN1	-3333
MMP8	-3401
ADAM15	-3624
ADAMTS3	-4140
PHYKPL	-4163
P4HB	-4269
CAST	-4471
ADAM19	-5127
CD47	-5129
CDH1	-5398
CAPN10	-5461
ADAM9	-5572
CEACAM1	-5677
ITGA7	-5684
CAPN15	-5768
ACTN1	-5854
COL11A2	-5946
NCSTN	-6510
CEACAM8	-6543
BSG	-6620
TNXB	-6803
TLL2	-6893
SDC1	-6917
MMP25	-6993
F11R	-7282
ICAM4	-7558
CAPN3	-7655
KLKB1	-7769
ADAM8	-8023
CEACAM6	-8040
ELN	-8087
CAPN1	-8124
MMP17	-8141
ICAM3	-8190
DMD	-8319
CTSG	-8376
ITGB2	-8620
COL9A2	-8654
COL28A1	-8674
ITGAM	-8682
MFAP2	-8693
ITGAX	-8712
ELANE	-8987
MMP1	-9020
ITGB7	-9121
FBN2	-9126
NRXN1	-9188
LAMA1	-9199
FBLN2	-9233
MMP3	-9381
ADAMTS16	-9492
ITGAL	-9631
MATN1	-9718
CAPN6	-9735
MADCAM1	-9874
CAPN12	-9950
COL4A4	-10003
ITGAE	-10024
ICAM5	-10165
COL9A1	-10245
MATN4	-10287
COL23A1	-10320
ITGB8	-10423
COL4A3	-10446
FBLN1	-10527
EFEMP1	-10546
ITGA2B	-10608
SPOCK3	-10694
COL14A1	-10697
MFAP5	-10877
COL4A5	-10902
LAMA2	-10937
MFAP4	-10976

---

Cell Cycle

Cell Cycle

	161
set	Cell Cycle
setSize	624
pANOVA	2.7e-12
s.dist	-0.164
p.adjustANOVA	9.01e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TUBAL3	-10839
TUBG1	-10336
E2F1	-10324
MSH5	-10298
PPP2R3B	-10275
H2AC20	-10202
POLA2	-10057
PKMYT1	-9959
CHTF18	-9939
INCENP	-9919
TUBA4A	-9905
PSMC3IP	-9870
E2F4	-9869
NCAPH	-9868
MCM5	-9835
AURKB	-9728
LIG1	-9694
E2F2	-9678
NSD2	-9659
SKA1	-9647

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TUBAL3	-10839
TUBG1	-10336
E2F1	-10324
MSH5	-10298
PPP2R3B	-10275
H2AC20	-10202
POLA2	-10057
PKMYT1	-9959
CHTF18	-9939
INCENP	-9919
TUBA4A	-9905
PSMC3IP	-9870
E2F4	-9869
NCAPH	-9868
MCM5	-9835
AURKB	-9728
LIG1	-9694
E2F2	-9678
NSD2	-9659
SKA1	-9647
CCNE1	-9640
CDCA8	-9629
FOXM1	-9602
PLK1	-9566
TUBB1	-9553
CDT1	-9526
HJURP	-9525
SYCE2	-9511
MCM10	-9508
PRKAR2B	-9494
ESPL1	-9438
MCM4	-9413
UIMC1	-9373
MCM7	-9356
CENPT	-9354
SPC24	-9341
CDC25A	-9316
H2AC18	-9274
KIF20A	-9255
MCM2	-9218
CDC6	-9194
MYBL2	-9180
ATRIP	-9167
CENPM	-9144
RAD9A	-9140
PIF1	-9116
H2BC9	-9109
CDC25C	-9107
NUP210	-9091
FEN1	-8998
H2BU1	-8956
MCM3	-8945
CDCA5	-8939
KMT5A	-8916
CDK11A	-8911
CDC20	-8856
POLD1	-8854
ZWINT	-8848
NUP85	-8821
AAAS	-8812
CDK11B	-8759
TUBGCP3	-8751
RNF8	-8732
GTSE1	-8696
CCND3	-8691
MAX	-8680
HAUS8	-8640
CENPI	-8637
TK1	-8621
RRM2	-8611
GINS4	-8604
CDC45	-8576
CENPO	-8559
PPME1	-8523
CLSPN	-8477
MASTL	-8454
POLE	-8450
KNTC1	-8444
CEP72	-8394
CHEK2	-8387
TFDP1	-8357
ORC6	-8295
TUBGCP4	-8276
CDKN2C	-8275
TUBB	-8269
LMNB1	-8263
NCAPH2	-8224
SFI1	-8118
RPA1	-8065
HAUS5	-8036
AURKA	-7985
TUBB2B	-7932
GINS1	-7920
CENPJ	-7919
RFC5	-7869
RAD51	-7867
HAUS2	-7758
DSN1	-7750
CCNB2	-7711
CCNA1	-7689
TPX2	-7672
NUP93	-7651
KAT5	-7619
UBE2C	-7617
NCAPD3	-7607
NCAPG2	-7557
CEP192	-7509
CDC25B	-7508
WEE1	-7491
BABAM1	-7480
OIP5	-7456
DHFR	-7420
RCC2	-7387
PRKCB	-7370
KIF23	-7368
CDK2	-7359
SGO1	-7343
E2F3	-7342
ORC1	-7325
NDE1	-7274
EXO1	-7263
PCNA	-7230
CNTRL	-7193
CCNE2	-7189
CTC1	-7110
MCM6	-7098
GINS2	-7046
PSMC4	-6992
TP53	-6976
DMC1	-6969
RANGAP1	-6931
SKP2	-6928
PPP2R5B	-6921
NCAPD2	-6899
CENPH	-6827
WRAP53	-6796
ZW10	-6777
CENPF	-6764
SYCP3	-6749
CCNA2	-6737
CDKN2D	-6727
ANAPC1	-6719
CCNB1	-6690
BRCA2	-6663
SSNA1	-6617
DNA2	-6552
LIN52	-6487
POLD4	-6484
NUP42	-6458
KIF2C	-6434
PSMD9	-6396
NUP214	-6384
SUN2	-6311
FBXO5	-6279
TFDP2	-6274
POM121	-6266
REC8	-6261
ESCO2	-6252
TYMS	-6202
BLM	-6160
RAD51C	-6105
PLK4	-6092
TUBA1B	-6081
PTTG1	-6071
BUB1	-6067
ANAPC7	-6043
BIRC5	-6037
PSMF1	-6034
BARD1	-6014
RBL1	-5989
POLA1	-5986
CENPE	-5949
VRK1	-5940
DIDO1	-5927
PSMD11	-5926
TPR	-5915
NUP43	-5897
FZR1	-5888
TUBB4B	-5873
RFC4	-5863
PCNT	-5838
MAPK1	-5806
PPP2R2D	-5801
ANAPC4	-5798
RAE1	-5771
RBBP7	-5724
RBBP4	-5692
PSMD3	-5686
ORC5	-5679
MAU2	-5674
NDC80	-5671
CENPK	-5623
SMC2	-5613
MZT2A	-5611
RFC2	-5605
BUB1B	-5578
MDC1	-5566
MND1	-5560
MLH1	-5543
PSMD2	-5529
CENPL	-5522
CENPN	-5519
CKAP5	-5414
NUP188	-5399
VPS4A	-5394
YWHAH	-5336
KIF18A	-5321
CHMP4B	-5304
NEK2	-5272
CHEK1	-5253
RTEL1	-5226
NCAPG	-5217
TUBGCP6	-5188
BRIP1	-5168
SMC3	-5155
RHNO1	-5153
MCM8	-5135
KNL1	-5115
TMPO	-5097
RAD17	-5076
PSMD7	-5071
CENPU	-4987
ANAPC2	-4981
CENPC	-4972
H2AZ2	-4971
CEP131	-4955
CDK1	-4876
ANAPC15	-4852
PPP2R5A	-4796
PRIM1	-4694
LPIN1	-4688
TOPBP1	-4666
PSMC5	-4664
CENPW	-4658
RUVBL2	-4652
HDAC1	-4644
CHMP4A	-4624
BUB3	-4599
CHMP7	-4583
BRCA1	-4538
ALMS1	-4534
CEP250	-4502
HAUS3	-4444
NUP62	-4426
ERCC6L	-4419
DKC1	-4376
DYNLL2	-4285
HAUS4	-4274
RPA3	-4265
GMNN	-4259
TERF2	-4234
TOP3A	-4149
CSNK2B	-4147
CDC16	-4112
DYRK1A	-4055
UBE2I	-4049
RFC3	-4046
FKBPL	-4017
PHF8	-4003
NUP37	-3999
NUF2	-3997
DCTN3	-3989
POLE2	-3978
TUBA1C	-3969
SPC25	-3880
DCTN2	-3876
H2BC15	-3870
PPP2R5D	-3841
STAG3	-3814
NUP98	-3797
CKS1B	-3791
PSMB2	-3751
SYNE2	-3748
NUP50	-3737
MAD2L1	-3735
CHMP2A	-3718
CDC7	-3717
NUMA1	-3715
NUDC	-3690
EMD	-3686
CDC23	-3676
PMF1	-3663
TUBGCP2	-3645
CDC27	-3643
POM121C	-3641
AKT2	-3639
ORC3	-3618
ORC2	-3617
OPTN	-3493
PSMD4	-3492
EP300	-3453
CDKN2A	-3397
TUBG2	-3367
CENPA	-3325
PPP6C	-3313
GAR1	-3277
CDK7	-3248
RNF168	-3236
PPP6R3	-3226
HAUS7	-3218
CDK5RAP2	-3191
SIRT2	-3165
KPNB1	-3164
CHMP6	-3163
SMC4	-3151
CEP78	-3127
CABLES1	-3117
TOP2A	-3058
DAXX	-3032
BORA	-3016
NUP155	-3011
CHTF8	-2972
CSNK1D	-2925
SMC1A	-2919
MDM4	-2906
RPA2	-2828
POLR2H	-2768
TINF2	-2752
MIS18A	-2717
NUP160	-2679
LPIN2	-2668
UBB	-2665
POLD3	-2652
PSMA7	-2633
CEP76	-2604
VRK2	-2590
CCND2	-2569
PDS5A	-2557
H2BC12	-2546
EML4	-2544
CTDNEP1	-2534
RBX1	-2533
DBF4	-2525
RAD21	-2511
RFC1	-2507
PSMD6	-2501
RMI1	-2486
NDC1	-2483
CENPP	-2476
POLE3	-2469
TERF2IP	-2461
NUP54	-2399
POLR2D	-2389
PSMB3	-2369
PSMC1	-2353
PSMB10	-2349
GSK3B	-2330
ODF2	-2322
RBBP8	-2310
NUP153	-2287
ANAPC16	-2268
H2AZ1	-2265
SYNE1	-2235
CC2D1B	-2219
CEP152	-2215
WRN	-2194
ZWILCH	-2178
RAB8A	-2157
CDKN1B	-2126
POLR2A	-2097
PRIM2	-2093
E2F5	-2078
SKA2	-2063
NUP205	-2044
LBR	-2042
PSMC2	-2035
PIAS4	-2032
RMI2	-1989
RAB1B	-1935
HAUS1	-1821
RAD1	-1804
ANKLE2	-1645
CEP43	-1637
DCTN1	-1587
CUL1	-1579
NIPBL	-1559
RAN	-1554
MIS12	-1526
HAUS6	-1519
RCC1	-1456
MIS18BP1	-1452
SEH1L	-1420
ACD	-1410
ABL1	-1394
HERC2	-1369
POLR2E	-1310
SDCCAG8	-1294
WAPL	-1277
LEMD2	-1269
H2BC21	-1250
PSMB8	-1241
CLASP1	-1213
POLR2B	-1143
LIN37	-1118
PRKACA	-1109
ENSA	-1066
PAFAH1B1	-1031
LYN	-973
POT1	-965
ESCO1	-960
UBE2S	-944
CEP57	-881
HMMR	-861
SGO2	-810
CCP110	-805
POLR2I	-790
DSCC1	-778
PSMD5	-770
PSMC6	-713
GOLGA2	-705
MAPK3	-640
POLR2J	-622
CEP164	-602
XPO1	-557
AKT1	-542
CSNK2A1	-520
PSMA1	-487
PSME4	-458
ACTR1A	-418
PPP1R12B	-386
NUP107	-374
PPP2R1A	-370
PSMD12	-334
ANAPC5	-329
PSMB1	-262
BRCC3	-252
PSMB9	-203
PSMC3	-201
LIN9	-185
GORASP1	-139
TUBGCP5	-134
LPIN3	-126
RAD50	-107
PSMB6	-57
NUP88	1
PSMB7	43
ITGB3BP	55
UBA52	75
KIF2A	78
BTRC	85
SRC	116
STAG1	144
IST1	217
PTK6	337
TERT	365
CEP290	375
ORC4	497
PSMD1	535
H2AJ	558
PPP1R12A	592
ATR	758
ARPP19	837
PSMA6	883
CDK6	894
POLE4	967
NHP2	975
TAOK1	1024
B9D2	1036
NOP10	1046
ANAPC11	1105
PPP2R5C	1128
DYNC1H1	1136
MRE11	1137
RUVBL1	1258
YWHAZ	1272
AKAP9	1305
OFD1	1386
NEDD1	1426
CLIP1	1429
SPAST	1435
MZT2B	1457
YWHAB	1461
YWHAG	1463
DYNC1LI2	1502
PCM1	1521
SKP1	1522
NEK7	1527
ATM	1536
PSME1	1537
MAPRE1	1548
POLR2G	1641
LCMT1	1651
CENPQ	1655
CDK4	1682
H3-3A	1684
POLD2	1717
CEP70	1720
NUP58	1820
PDS5B	1834
PSMD13	1835
PSME3	1870
TUBB2A	1872
PSMB4	1921
CNEP1R1	1977
PSMA4	2112
SHQ1	2114
CSNK1E	2117
NUP133	2121
PHF20	2176
PSMD14	2194
PSMD8	2211
RBL2	2227
SET	2242
CDKN1C	2262
JAK2	2269
CLASP2	2290
LEMD3	2357
NSL1	2374
LIN54	2396
DYNC1LI1	2403
FBXL18	2453
UBC	2572
PPP2R2A	2601
CHMP3	2637
MDM2	2666
SMARCA5	2720
PRDM9	2735
UBE2V2	2741
TUBA8	2771
RAD9B	2772
POLR2C	2776
H2BC11	2796
HDAC8	2917
MCPH1	2974
HSP90AA1	2976
RPS27	3034
PSMA3	3043
TERF1	3234
CHMP2B	3333
PPP2R5E	3349
MAD1L1	3350
PPP2CA	3353
CETN2	3356
CEP63	3374
BANF1	3385
CEP135	3387
HSP90AB1	3401
POLR2F	3439
PSMA5	3448
NME7	3474
SYCE1	3497
SUN1	3498
PSMD10	3520
NDEL1	3609
CDC14A	3612
FKBP6	3690
ANKRD28	3697
CCNH	3710
UBE2E1	3718
RSF1	3719
SEC13	3773
NEK9	3782
MZT1	3819
GORASP2	3884
TUBB6	3913
NUP35	3944
H2AC6	3982
STAG2	4003
HUS1	4035
RANBP2	4107
UBE2N	4169
TNPO1	4177
PPP1CC	4305
PSMA2	4316
E2F6	4336
BLZF1	4367
PCBP4	4375
NBN	4414
POLR2L	4485
AHCTF1	4509
RB1	4514
SUMO1	4538
RPS27A	4555
ANAPC10	4582
YWHAE	4598
ATRX	4603
SPDL1	4612
GINS3	4771
DYNC1I2	4775
CEP41	4822
NINL	4987
POLR2K	5037
PSME2	5088
NPM1	5146
MYC	5260
CSNK2A2	5397
MLH3	5433
MNAT1	5649
H2BC5	5661
RAB2A	5669
H2BC4	5688
PPP2R1B	5744
YWHAQ	5782
RAB1A	5784
CDKN2B	5830
PPP1CB	5905
ZNF385A	5979
TEN1	6006
TP53BP1	6204
FBXW11	6219
DYNLL1	6259
CDC26	6280
SEM1	6281
USO1	6347
TUBB3	6485
UBE2D1	6535
FBXL7	6637
STN1	6741
SYCP2	6951
PPP2CB	7026
PSMB5	7356
LMNA	7480
DYNC1I1	7586
CCND1	7921
SFN	8208
AKT3	8339
AJUBA	8365
NEK6	8414
PRKCA	8540
HSPA2	8558
TUBA1A	8594
PHLDA1	8951
CDKN1A	9070
CHMP4C	9159

---

Developmental Biology

Developmental Biology

	295
set	Developmental Biology
setSize	797
pANOVA	2.73e-12
s.dist	0.146
p.adjustANOVA	9.01e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ANK3	9178
RARB	9177
RND1	9173
DSP	9163
ROBO2	9154
EGR2	9108
ANGPTL4	9103
SPINK5	9100
SH3GL2	9093
CDKN1A	9070
PFN2	9056
CDH2	9040
MYO10	9031
DOK6	9007
WNT4	8967
FGF2	8938
KRT18	8926
ITGA2	8913
WWTR1	8894
KRT17	8826

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ANK3	9178
RARB	9177
RND1	9173
DSP	9163
ROBO2	9154
EGR2	9108
ANGPTL4	9103
SPINK5	9100
SH3GL2	9093
CDKN1A	9070
PFN2	9056
CDH2	9040
MYO10	9031
DOK6	9007
WNT4	8967
FGF2	8938
KRT18	8926
ITGA2	8913
WWTR1	8894
KRT17	8826
TRPC6	8822
DOK5	8772
NGEF	8744
SLIT2	8717
RPS6KA6	8716
NCAM1	8711
JUN	8707
HES1	8677
ITGAV	8674
NTN1	8671
TSC22D1	8668
SHC3	8665
SEMA5A	8650
SDC2	8628
CDON	8621
FLRT3	8608
KLF4	8604
NRP2	8596
SEMA3E	8592
ROBO1	8562
SALL4	8548
PRKCA	8540
RHOC	8521
EPHA2	8482
SCN2B	8412
MEF2C	8405
AJUBA	8365
MSI1	8358
AKT3	8339
ENAH	8320
CDH15	8296
UNC5B	8292
EFNB3	8251
MEF2A	8243
UNC5C	8230
SRGAP3	8203
ABL2	8168
STX1A	8158
CTNNB1	8135
DHH	8124
SCD5	8111
ITGA5	8051
CACNA1D	8040
SEMA6D	8031
ITGA10	8010
KALRN	7990
SHTN1	7916
RPSA	7908
NEO1	7892
GFRA1	7874
TRPC4	7857
CYP51A1	7850
RPL9	7848
FARP2	7847
GCK	7807
PERP	7790
EPHA3	7778
DPYSL4	7777
PIK3R3	7755
EFNB2	7754
EFNA5	7685
KRT10	7661
MET	7591
SOX9	7579
DSC3	7528
GPC1	7465
SPAG9	7427
ADAM10	7409
ADGRG6	7400
SRGAP1	7396
TCF4	7393
PSMB5	7356
RDX	7257
PLXNA2	7217
COL4A1	7213
YES1	7207
NAB2	7201
HOXD1	7168
SCN4B	7127
MAML2	7097
SHC1	7085
DOCK1	7071
DPYSL3	7068
LIPN	7054
DSG2	7031
ARHGAP39	7018
CEBPB	6956
LHX4	6937
DSC2	6896
CACNA1C	6871
RPS27L	6864
GFRA2	6847
PTK2	6843
RPS6KA3	6833
CDK5	6809
ABLIM1	6780
GSPT2	6768
HOXC4	6762
HOXB2	6757
HMGCR	6745
AKAP5	6716
FOXO1	6686
KRT8	6647
RARG	6620
NRCAM	6549
LEF1	6513
DLG1	6499
RPL41	6462
ITGB1	6439
PCGF2	6331
WASL	6292
KRT16	6288
SEM1	6281
COL6A2	6270
CDH4	6187
CTNNA1	6175
SCN1B	6122
DKK1	6119
CBFB	6101
RPS2	6089
RUNX1	6068
TIAM1	6053
MED19	6051
FRS2	6026
MED31	6021
RPS9	6020
CHD9	5977
RHOB	5934
NAB1	5933
RPL18A	5926
PMP22	5921
HSPA8	5871
EPAS1	5851
PKP3	5827
ADAM22	5813
CEBPD	5811
HOXD3	5781
RPS13	5739
RPLP0	5695
RPL24	5693
H2BC4	5688
EPHA4	5682
H2BC5	5661
CACNB4	5659
SMAD3	5657
CLTA	5641
EFNA1	5637
CRMP1	5634
RPL39L	5631
ELOB	5627
MED21	5605
ONECUT3	5523
RPS3A	5482
PLXNA1	5470
COL6A1	5449
RPL36A	5419
CSNK2A2	5397
HOXB4	5389
RPL7	5370
RPL37A	5366
NCOA3	5361
RPL23A	5347
DOK4	5311
HRAS	5288
SEMA7A	5268
MYC	5260
EPHB1	5249
MED13	5225
RPL13A	5213
RPL13	5185
RPS16	5179
GAB1	5161
MYH10	5152
RPL15	5149
PRKAR2A	5114
RELA	5093
RPL4	5091
PSME2	5088
DSCAML1	5077
NRAS	5076
MED14	5048
RPL36AL	5042
POLR2K	5037
JUP	5010
RPS11	4999
SPTBN5	4973
SRGAP2	4964
PIK3CA	4947
RPS19	4946
BOC	4904
RPL32	4893
YAP1	4884
RPL39	4878
RPL29	4831
CCNC	4828
RPL31	4824
ST8SIA4	4814
RPS10	4796
TRPC1	4785
RPL19	4738
PI3	4676
CNTN1	4671
ELOC	4667
KRT1	4642
FGFR1	4638
ERBB2	4628
TBL1X	4600
NR2F2	4568
ITGA9	4558
RPS27A	4555
RPL28	4540
ABLIM2	4539
LIMK1	4536
DAG1	4533
ETF1	4529
RPL18	4499
POLR2L	4485
RPL7A	4483
ITGA1	4457
SPTAN1	4430
RPL3	4426
EZR	4396
PLXNA3	4379
PRNP	4354
PSMA2	4316
RPL17	4292
RPS3	4276
RPL27	4270
RPL23	4262
RPL6	4249
KAZN	4248
RPL35A	4246
RPS18	4239
GSC	4230
RPS23	4200
RPL10A	4189
RPS17	4171
RPS5	4154
RPL12	4132
PLXNB1	4116
RPS8	4115
HOXA1	4099
SIAH1	4064
COL6A3	4021
COL4A2	4008
RPL8	4000
NANOG	3997
TRIO	3987
UTRN	3984
H2AC6	3982
PSENEN	3970
RPL14	3947
CXCL12	3938
MAP2K6	3936
RPS24	3930
RPL34	3928
EPHB4	3918
EFNB1	3902
COL9A3	3899
RPL37	3888
RPS25	3886
DRAP1	3881
RPS7	3878
RPL26	3817
KRAS	3793
SCN4A	3748
RPL35	3741
ARHGEF12	3727
TBL1XR1	3726
RPS12	3713
RPS15A	3668
CLTB	3663
RPL10	3638
PLXND1	3583
RPL38	3564
HOXD4	3535
ACTG1	3525
PSMD10	3520
RPL36	3513
RPS6	3469
RPS21	3461
PSMA5	3448
SHANK3	3441
POLR2F	3439
NRP1	3435
NCK2	3415
RPL30	3402
HSP90AB1	3401
RPS15	3394
HOXB3	3393
CREB1	3358
NTN4	3335
DLG4	3329
DLG3	3317
MED23	3313
FAU	3307
PRKACB	3303
SDCBP	3297
LAMC1	3285
RPL22	3284
RPL21	3212
RPS29	3177
MED17	3147
MEF2D	3127
EFNA4	3102
RARA	3069
MAPK8	3067
RPL5	3062
RPL22L1	3056
PSMA3	3043
RPS27	3034
GRB10	3025
HSP90AA1	2976
MMP9	2968
ROCK2	2967
CACNA1H	2957
RRAS	2921
RPS20	2909
EPHB3	2877
VAV2	2828
FYN	2820
H2BC11	2796
POLR2C	2776
STAT3	2744
MED13L	2731
NCK1	2702
RPLP1	2674
SCN2A	2631
MYL6	2625
RPL27A	2608
SCN11A	2598
PAK4	2593
UBC	2572
RPS4Y1	2516
EPHA7	2515
PAK2	2496
ARHGEF28	2454
LAMB1	2429
PKNOX1	2392
RGMB	2363
SUZ12	2329
RASA1	2313
ACVR2A	2306
CLASP2	2290
PSMD8	2211
PSMD14	2194
ARHGAP35	2168
PIAS2	2164
ACTR2	2139
MYH11	2133
PSMA4	2112
KMT2A	2086
PLCG1	2063
TGS1	2055
RHOA	2032
RPL11	2004
RPLP2	1969
PIK3R1	1940
FAM120B	1925
PSMB4	1921
ITGB3	1908
HDAC2	1907
PSME3	1870
PSMD13	1835
NCBP1	1828
RPS28	1779
PTPN11	1777
RAC1	1751
MAFB	1747
APH1B	1738
H3-3A	1684
CDK4	1682
POU5F1	1646
POLR2G	1641
MED7	1590
PIK3CB	1574
PSME1	1537
RPL26L1	1510
PAK6	1445
UNC5A	1355
MYL12B	1306
AP2S1	1304
CLTC	1234
MAPK11	1224
RPS14	1220
RBBP5	1205
TGFB1	1195
SMAD4	1118
PPP3CB	1050
NFASC	1025
CDC42	1019
NCOA2	1018
ARPC5	990
EPHB2	956
TNF	897
ALCAM	891
FURIN	885
PSMA6	883
DNM3	864
PPARGC1A	851
SCN3B	834
RPS6KA2	831
SCN3A	790
VAV3	765
CD72	736
NCBP2	687
ARHGEF7	625
TRPC3	590
PKP4	588
PTPRC	563
H2AJ	558
PSMD1	535
PRX	395
SCN1A	366
APH1A	346
ARHGEF11	339
PIP5K1C	248
HELZ2	226
ARTN	159
RPS4X	120
SRC	116
SMARCD3	95
MED6	81
UBA52	75
PSMB7	43
CACNB3	32
PSMB6	-57
PDLIM7	-89
SOS2	-191
PSMC3	-201
PSMB9	-203
PAX6	-227
PLXNB3	-244
PSMB1	-262
VLDLR	-276
KMT2C	-286
RPS6KA5	-310
PSMD12	-334
FOXA2	-341
TGM1	-410
PSME4	-458
CAPNS1	-484
PSMA1	-487
GATA2	-493
CSNK2A1	-520
ARPC3	-538
AKT1	-542
PAGR1	-546
MAGOHB	-551
AGRN	-570
MED1	-607
MYH14	-618
POLR2J	-622
MAPK3	-640
MED27	-697
DNM1	-701
PSMC6	-713
PSMD5	-770
POLR2I	-790
ZNF638	-801
NOTCH1	-829
MAML1	-851
RANBP9	-858
MED4	-863
PITPNA	-900
MYL12A	-911
LYN	-973
MAGOH	-1001
TEAD1	-1017
EBF1	-1024
GIT1	-1058
EVL	-1068
PRKACA	-1109
ACTR3	-1117
POLR2B	-1143
CUL2	-1189
CLASP1	-1213
SOS1	-1232
PSMB8	-1241
H2BC21	-1250
POLR2E	-1310
TYROBP	-1313
DPYSL2	-1342
CNTNAP1	-1362
ABL1	-1394
SNW1	-1443
RPL3L	-1445
NFKB1	-1447
BNIP2	-1486
SCN8A	-1490
SMAD2	-1532
PPARA	-1551
CACNB1	-1590
PML	-1609
SPTBN4	-1668
MED11	-1681
GSPT1	-1686
MAMLD1	-1707
FOXO3	-1726
EIF4A3	-1789
USP33	-1799
ARPC2	-1824
ADGRV1	-1856
MAML3	-1887
CNOT6	-1888
HOXA3	-1906
MED10	-1973
PSMC2	-2035
CACNA1I	-2082
POLR2A	-2097
TREM2	-2101
MSN	-2114
ABLIM3	-2145
SMARCA4	-2206
HOXA4	-2242
ROCK1	-2243
ACVR2B	-2257
PKP1	-2259
H2AZ1	-2265
KDM6A	-2275
AP2B1	-2296
GSK3B	-2330
PSMB10	-2349
PSMC1	-2353
AP2M1	-2365
PSMB3	-2369
POLR2D	-2389
DEK	-2409
PSPN	-2456
NCOR2	-2498
PSMD6	-2501
RBX1	-2533
TCF12	-2539
RBM8A	-2541
H2BC12	-2546
KAT2A	-2565
WNT1	-2568
LGI4	-2599
PSMA7	-2633
UBB	-2665
PSEN2	-2704
AP2A2	-2709
STX1B	-2735
MEIS1	-2758
POLR2H	-2768
HOXA2	-2780
SEMA3A	-2806
EED	-2827
MED28	-2882
PBX1	-2883
MED29	-2913
PLXNC1	-2932
CDK19	-2936
RXRA	-3018
ARPC1A	-3033
MMP2	-3039
GAB2	-3076
SEMA4D	-3110
UPF2	-3168
KMT2D	-3199
NR5A2	-3205
GATA6	-3224
RBPJ	-3233
SPTBN1	-3307
PSEN1	-3333
YY1	-3364
GRIN2B	-3420
NUMB	-3434
CAP1	-3436
EP300	-3453
PSMD4	-3492
LIMK2	-3521
MED26	-3572
MYL9	-3598
AKT2	-3639
MAP2K1	-3701
PSMB2	-3751
DOK1	-3803
LPL	-3834
MAPK7	-3865
H2BC15	-3870
MED16	-3879
RNPS1	-3910
EIF4G1	-3934
CASC3	-4082
MED9	-4105
CSNK2B	-4147
ADIRF	-4150
ITSN1	-4254
RPS6KA4	-4266
FGF9	-4287
MYO9B	-4302
CACNG8	-4326
PIK3R2	-4348
IL6R	-4409
NCOA6	-4410
THRAP3	-4440
MED30	-4457
SLIT3	-4470
EVPL	-4603
MAPK12	-4620
PSMC5	-4664
CFL1	-4675
MAPK13	-4730
ARPC4	-4772
TLN1	-4792
PTGDS	-4837
NCOR1	-4871
KAT2B	-4874
ZSWIM8	-4900
MED22	-4964
H2AZ2	-4971
PAK1	-5016
PSMD7	-5071
MAP2K2	-5121
PABPC1	-5187
CACNG2	-5235
FOXP1	-5307
MAPK14	-5334
ZFPM2	-5356
MED20	-5379
HHEX	-5389
LYPLA2	-5400
RPS26	-5402
MBP	-5415
CREBBP	-5451
PSMD2	-5529
ROBO3	-5535
WDR5	-5637
MED12	-5647
PSMD3	-5686
NCOA1	-5688
RBBP4	-5692
RGMA	-5701
CD24	-5710
RBBP7	-5724
MED8	-5767
MAPK1	-5806
HDAC3	-5834
SPI1	-5846
EPHA1	-5887
PSMD11	-5926
PSMF1	-6034
CDK8	-6062
MED25	-6091
MYB	-6176
MED15	-6230
UPF3A	-6253
LIN28A	-6268
TFDP2	-6274
RAP1GAP	-6288
MED18	-6320
PSMD9	-6396
GRB2	-6402
WNT10B	-6405
PPARG	-6410
ST14	-6411
ADAM23	-6430
ARPC1B	-6441
ZNF467	-6499
NCSTN	-6510
SCN9A	-6517
EGFR	-6577
ACTB	-6627
CSTA	-6630
MYH9	-6652
SEMA6A	-6677
ASH2L	-6711
LGI2	-6724
VASP	-6826
ZNF335	-6860
SH3KBP1	-6879
KIF4A	-6923
DPPA4	-6925
MED24	-6936
PSMC4	-6992
EFNA3	-7014
KCNQ3	-7047
CACNB2	-7054
HIF3A	-7141
MPZ	-7160
PIK3CD	-7175
ACVR1B	-7243
KLF5	-7250
SPTA1	-7256
CSF3R	-7270
SPTBN2	-7281
CDK2	-7359
CTCF	-7415
SREBF2	-7451
CD36	-7512
PFN1	-7552
CEBPE	-7564
EZH2	-7660
TCF3	-7684
DNM2	-7699
PLXNA4	-7704
SLIT1	-7717
SREBF1	-7815
SIAH2	-7829
PTPRA	-7886
TAL1	-7983
PRKCQ	-7988
AP2A1	-8034
CAPN1	-8124
FLI1	-8169
PKLR	-8210
RET	-8214
NR6A1	-8309
ANK1	-8328
ANK2	-8329
TFDP1	-8357
ADAM11	-8412
AMH	-8433
CARM1	-8442
PCK1	-8455
CXCR4	-8632
COL9A2	-8654
ACVR1C	-8657
CCND3	-8691
NELL2	-8728
RPS6KA1	-8768
DOK2	-8797
CHL1	-8805
FES	-8852
CAP2	-8853
LDB1	-8870
EPHB6	-8880
H2BU1	-8956
SEMA4A	-9060
AGAP2	-9105
H2BC9	-9109
SPTB	-9120
PAK3	-9138
CLTCL1	-9153
UPF3B	-9197
LAMA1	-9199
H2AC18	-9274
KRT13	-9618
FABP4	-9623
L1CAM	-9726
TCHH	-9748
LEFTY2	-9794
PAXIP1	-9883
HNF4A	-9933
CEBPA	-9974
COL4A4	-10003
ADIPOQ	-10063
CNTN2	-10101
SLC2A4	-10155
CACNA1G	-10182
H2AC20	-10202
PLIN1	-10207
GAP43	-10208
COL9A1	-10245
CDK5R1	-10308
E2F1	-10324
PKP2	-10362
COL4A3	-10446
MEF2B	-10453
KRT72	-10480
GFI1	-10533
LEP	-10602
ITGA2B	-10608
KRT23	-10632
SCN7A	-10726
IRS2	-10805
PCSK6	-10808
LGI1	-10809
DRP2	-10810
EPHA10	-10860
PPL	-10874
COL4A5	-10902
EOMES	-10921
LAMA2	-10937
FGF10	-10944
RELN	-10963

---

Signal Transduction

Signal Transduction

	1139
set	Signal Transduction
setSize	2166
pANOVA	5.92e-12
s.dist	0.0903
p.adjustANOVA	1.91e-10

Top enriched genes

Top 20 genes

GeneID	Gene Rank
DNER	9198
NGF	9195
INHBA	9192
SOCS3	9188
IL6	9183
BMP2	9181
RARB	9177
MT-RNR2	9176
RND1	9173
EGR3	9166
SERPINE1	9164
DSP	9163
FOSB	9160
CYP26A1	9151
DUSP5	9139
RGS13	9119
SPP1	9117
PTPRZ1	9114
GNG4	9113
WNT16	9112

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
DNER	9198
NGF	9195
INHBA	9192
SOCS3	9188
IL6	9183
BMP2	9181
RARB	9177
MT-RNR2	9176
RND1	9173
EGR3	9166
SERPINE1	9164
DSP	9163
FOSB	9160
CYP26A1	9151
DUSP5	9139
RGS13	9119
SPP1	9117
PTPRZ1	9114
GNG4	9113
WNT16	9112
EGR2	9108
ADCYAP1	9095
SH3GL2	9093
SGK1	9086
CCL3	9084
NR4A1	9076
GJA1	9071
CDKN1A	9070
ADH4	9069
TNFRSF10D	9067
PFN2	9056
CXCL8	9054
ATP6V0D2	9049
LPAR3	9044
NTF3	9042
FFAR3	9041
RRAD	9030
DUSP4	9013
CD55	9004
GREM2	9002
CILP	8995
ADAM12	8987
SKIL	8984
FN1	8982
WNT4	8967
FOSL1	8956
CXCL2	8953
FGF2	8938
PDE4B	8930
CCL2	8929
ITGA2	8913
IER3	8900
WWTR1	8894
THBS1	8890
JUNB	8881
ADORA1	8876
LRRC1	8871
SPARC	8869
WWC1	8868
KLK3	8864
BAMBI	8863
FGF1	8861
RGS16	8860
CDC42EP5	8857
SCD	8853
DYNC2H1	8833
ACTN2	8832
TRPC6	8822
RGS3	8813
CALCR	8812
WNT7B	8805
DGKI	8804
ARC	8797
TIAM2	8794
CKB	8792
BAIAP2L1	8784
LPAR4	8770
GPR15	8766
EGR1	8756
NGEF	8744
ADCY1	8733
LAMB3	8732
TGFBR1	8727
P2RY6	8726
WNT9A	8725
GPR4	8722
NCAM1	8711
JUN	8707
CCL4	8697
PGF	8694
ETV4	8688
CRABP2	8687
CCL22	8678
HES1	8677
ITGAV	8674
SHC3	8665
RND3	8655
SPATA13	8653
ANOS1	8641
GAS1	8640
CMA1	8634
SOWAHC	8630
SNAI1	8629
CDON	8621
RHOBTB1	8614
ID3	8612
FLRT3	8608
GPR183	8606
SPRY1	8599
NRP2	8596
IL1RL1	8591
PDGFC	8577
CRHR2	8573
FGFR2	8563
JUND	8555
AMOTL1	8554
SALL4	8548
AREG	8544
PRKCA	8540
MAPK6	8537
RHOC	8521
APLN	8517
SPPL2A	8509
FOS	8501
GNA14	8492
EPHA2	8482
ADRA1B	8475
PCDH7	8466
DNAJB1	8462
KDR	8459
AXIN2	8451
FZD5	8447
SOX7	8443
HBEGF	8440
MYO6	8429
NOG	8428
FZD8	8423
USP13	8422
MDK	8421
VEGFA	8413
MEF2C	8405
APLNR	8401
PTGER1	8398
PPP3CA	8367
SOX4	8351
S1PR3	8350
AKT3	8339
PRKCZ	8334
SPRED3	8330
GLI3	8326
PTPRK	8325
PTHLH	8314
AMOT	8309
PYGO1	8308
ID1	8298
STAT1	8277
HIF1A	8270
FGFRL1	8267
SMAD6	8264
SPRY2	8256
FGFBP2	8252
SH3PXD2A	8247
MEF2A	8243
DLL4	8237
GNGT2	8231
APOE	8221
SPRED1	8216
SFN	8208
SRGAP3	8203
WNT3	8199
RGS1	8198
JAG1	8182
ABL2	8168
PRKG1	8155
RGS2	8154
PMEPA1	8143
CTNNB1	8135
SH3RF1	8129
DHH	8124
ATP6V1B2	8121
SWAP70	8108
STARD13	8107
TNFAIP1	8103
ALDH1A3	8102
ADRA2A	8098
ATP6V1A	8071
NGFR	8066
GIPR	8046
ABHD6	8037
LGR4	8026
PLA2G4A	8021
RAMP3	7993
KALRN	7990
LRP6	7986
DGKH	7982
ARL4C	7975
NOTUM	7971
SYDE2	7969
DOCK7	7953
GALNT3	7951
DST	7934
HCAR2	7930
AMOTL2	7928
CCND1	7921
TGFA	7915
STMN2	7904
CRH	7897
TPM4	7890
SSTR2	7885
RTKN	7884
PRKCE	7875
GFRA1	7874
CHRM3	7870
TNS3	7856
HECW1	7854
FARP2	7847
GNA13	7844
ABI2	7835
ALDH1A2	7834
ATP6V1B1	7822
ZDHHC9	7821
GNB4	7820
CDC42EP1	7808
STAP2	7785
PDGFA	7782
CHN1	7772
ADCYAP1R1	7768
CAMK2A	7758
PIK3R3	7755
DZIP1	7751
RIPK2	7748
FZD1	7747
ABCG1	7734
ARHGAP5	7722
RBFOX2	7718
FLT1	7672
PARD3	7660
CHN2	7639
SHB	7631
ID4	7626
P2RY10	7610
APOC2	7593
S100B	7592
MET	7591
DLC1	7588
DYNC1I1	7586
SOX9	7579
PLEKHG1	7564
SOX17	7547
XIAP	7541
ATP6V1H	7533
RHOD	7531
PLCB4	7518
FARP1	7514
EREG	7509
PPP1R15A	7508
CCR1	7504
PCSK5	7503
CAMK2D	7500
PREX2	7486
AVPR1A	7477
TGFBR2	7472
FGD1	7469
SMPD3	7453
BMPR1A	7452
FGF18	7449
CTNND1	7442
ARHGAP31	7433
OPN3	7431
IRS1	7429
ADAM10	7409
EPSTI1	7402
SRGAP1	7396
TCF4	7393
LATS2	7376
DUSP2	7374
TJP1	7367
PTH1R	7363
DACT1	7360
ATP6V1G1	7359
ROR1	7357
PSMB5	7356
EDNRA	7353
FMNL3	7322
PRKAR1A	7315
EVC	7300
GPR161	7294
LINGO1	7293
LMAN1	7288
BCAR1	7283
NFATC1	7280
RHOJ	7274
TNFRSF1A	7263
DUSP1	7256
MRAS	7234
ARHGEF3	7221
HEYL	7214
COL4A1	7213
KIF3A	7212
YES1	7207
NAB2	7201
DOCK4	7196
CD86	7194
HCAR3	7181
BMPR2	7171
TNFRSF10B	7155
TEK	7119
HEY2	7111
ITPR2	7099
MAML2	7097
SHC1	7085
F2RL1	7074
DOCK1	7071
CX3CL1	7065
MST1R	7037
DSG2	7031
PPP2CB	7026
ARHGAP39	7018
NOTCH4	6990
FGFR3	6978
MAGED1	6969
CYFIP1	6961
SYDE1	6947
TWF1	6939
OTUD7B	6913
CDC42EP3	6907
GPR176	6898
GOLGA8R	6868
ARHGAP28	6858
ATP6V0E1	6852
GFRA2	6847
PTK2	6843
TAC1	6837
GARRE1	6835
RPS6KA3	6833
CDH5	6832
RGS10	6831
DOCK10	6825
ATP6V1D	6815
BAIAP2L2	6813
CDK5	6809
PRKAA2	6802
FZD10	6792
KIDINS220	6785
KSR2	6779
PTPN3	6775
ACVRL1	6765
ATP6V1C1	6756
ATP2A1	6754
S1PR1	6746
MIB1	6725
PARD6A	6715
GNG11	6712
GABRB2	6707
FOXO1	6686
SMAD7	6681
KIF7	6674
TAS2R5	6634
VWF	6629
PDGFB	6622
RARG	6620
DAB2IP	6607
RGL1	6602
FAM169A	6596
PKN3	6587
NCKAP1	6584
SLC4A7	6573
ATP6V1E1	6572
WNT5B	6567
GOPC	6559
VANGL1	6554
SMO	6546
IL3RA	6545
UBE2D1	6535
BAIAP2	6532
APOC1	6527
NOTCH2	6518
LEF1	6513
DLG1	6499
RAMP2	6490
RYK	6486
TMEM59	6484
ARHGAP44	6479
MSI2	6475
KLK2	6469
RGL3	6461
RGS9	6460
RAPGEF4	6457
PDGFD	6444
ITGB1	6439
FAM91A1	6431
DISP2	6420
ITPR3	6415
ADM2	6386
PDE8A	6378
F2R	6377
RXRG	6375
ATP6V1F	6364
DLG5	6361
NDUFA5	6354
GRM6	6333
DNAL4	6332
BDKRB2	6329
STK3	6325
UACA	6304
WASL	6292
SEM1	6281
RASAL2	6272
COL6A2	6270
RAMP1	6260
DYNLL1	6259
ARHGEF17	6253
TAX1BP3	6245
SMAD5	6231
ITPR1	6224
PTPRU	6221
ROR2	6215
UHRF1BP1L	6200
ARHGEF19	6179
CTNNA1	6175
NR3C1	6171
ARHGEF35	6166
LPAR1	6162
GREB1	6139
SPINT1	6125
DKK1	6119
CDC42BPA	6117
ARHGEF33	6112
TNFAIP3	6107
CBFB	6101
RHOU	6095
GNG10	6094
RRAGA	6093
SOCS6	6090
RUNX1	6068
ARL13B	6059
TIAM1	6053
ICOS	6049
P2RY1	6041
EVC2	6029
FRS2	6026
ITCH	6011
TF	6008
GLI2	5994
SPOPL	5978
FZD7	5976
PDE7B	5973
SSTR5	5937
RHOB	5934
NAB1	5933
CRABP1	5925
WWP2	5922
FZD3	5912
DDX5	5910
PPP1CB	5905
SLK	5898
RAG2	5875
ZDHHC21	5870
RNF111	5865
IGF2	5853
EPAS1	5851
IL6ST	5838
ADGRE2	5833
CCL16	5831
CDKN2B	5830
STAM2	5822
DLL1	5796
GPR65	5789
BIRC2	5787
YWHAQ	5782
RALA	5761
LRP5	5749
ABHD17C	5748
BAD	5747
PPP2R1B	5744
GPSM1	5743
PNOC	5735
ACTA2	5734
ARHGAP29	5720
RHOBTB3	5708
WNT2B	5691
H2BC4	5688
CALCRL	5673
ERLEC1	5671
H2BC5	5661
SMAD3	5657
CLTA	5641
PDE6G	5635
WNT5A	5632
FAM135A	5619
PEA15	5601
CD274	5592
ARHGEF25	5577
LYPLA1	5547
MYLK	5532
ATP6V1E2	5521
ZNRF3	5514
NF1	5486
ANXA1	5485
PLXNA1	5470
CDC42EP2	5462
ADCY9	5457
COL6A1	5449
FFAR2	5443
CXCL16	5437
AXL	5435
INTU	5425
B4GALT1	5424
S1PR2	5422
TCF7L2	5418
DAGLA	5399
CSNK2A2	5397
DOCK9	5388
SAV1	5376
NCOA3	5361
TACR2	5319
PRKX	5301
PHC1	5297
HRAS	5288
MYC	5260
ADCY2	5254
FGD5	5252
STRAP	5247
FABP5	5238
BCL9	5183
TCF7L1	5181
GAB1	5161
KIF5B	5157
KLC2	5153
MYH10	5152
PIK3R4	5136
GNG2	5131
CHD4	5122
TNFRSF10A	5119
PRKAR2A	5114
DLAT	5110
ARHGAP42	5108
COPS2	5096
RELA	5093
PSME2	5088
CDC42EP4	5084
ADAM17	5082
NRAS	5076
RHPN2	5055
GPR68	5052
FILIP1	5041
POLR2K	5037
JUP	5010
APP	5003
SPTBN5	4973
SRGAP2	4964
BCL2	4959
PIK3CA	4947
MATK	4935
HSPE1	4930
PLEKHG2	4915
BOC	4904
PLG	4900
TRAT1	4898
TIA1	4885
YAP1	4884
CXCL3	4882
HEY1	4876
SMAD9	4869
FRK	4846
CCNC	4828
DUSP3	4816
MYO9A	4810
HSPB1	4806
DOCK6	4805
VANGL2	4803
LAMC3	4797
VIM	4793
FLRT1	4791
LINC01139	4780
RASA4	4778
DYNC1I2	4775
ARHGEF40	4765
ARHGEF10	4757
WWP1	4752
AGT	4741
HRH1	4733
BMI1	4727
LRRC7	4723
FERMT2	4707
FLRT2	4693
VAPA	4683
C1QBP	4675
CNTN1	4671
ARMCX3	4668
GTF2A2	4666
CNKSR2	4665
FGFR1	4638
OBSCN	4636
ERBB2	4628
CCNT1	4626
PDE2A	4615
SPDL1	4612
TBL1X	4600
YWHAE	4598
TNRC6A	4573
ANKRD26	4567
RDH11	4559
RPS27A	4555
RNF2	4554
POGLUT1	4545
ARHGEF15	4541
LIMK1	4536
GNA11	4530
CYSLTR1	4515
AHCTF1	4509
ITGA3	4507
PTPN13	4502
POLR2L	4485
TAB2	4482
DBN1	4481
RGS4	4476
CAMK4	4474
SH2B3	4453
SPTAN1	4430
RGS12	4420
CSNK1A1	4418
CXXC5	4397
ATP2A2	4372
HHAT	4349
DVL1	4321
CORT	4317
PSMA2	4316
CDC42BPB	4306
PPP1CC	4305
RPGRIP1L	4296
FOXO6	4280
TULP3	4277
LAMB2	4268
STRN	4254
TNKS	4242
DOCK5	4212
GNAI3	4207
PTPRS	4188
NOTCH3	4161
KITLG	4157
RHOBTB2	4119
PLXNB1	4116
SPHK1	4113
RANBP2	4107
PTEN	4060
AHCYL1	4052
VEGFC	4047
RAB4A	4039
CPD	4023
COL6A3	4021
PRKCH	4018
PDK3	4016
VAMP3	4013
CAV2	4012
COL4A2	4008
SHMT2	4004
STAG2	4003
TRIO	3987
LATS1	3983
H2AC6	3982
PSENEN	3970
CXCL12	3938
SMAD1	3920
PGR	3912
NPFFR1	3906
COL9A3	3899
DRAP1	3881
SRF	3866
FLT4	3859
PRKCI	3850
ARFGAP3	3842
GNAI1	3838
COPS4	3834
IL32	3833
YKT6	3827
DBT	3815
TMED2	3813
RIT1	3812
FZD9	3807
GALR1	3797
KRAS	3793
MFN1	3787
FSTL1	3781
SEC13	3773
DLG2	3767
WLS	3747
ARHGEF12	3727
TBL1XR1	3726
GTF2A1	3711
CLTB	3663
PEAK1	3655
PSAP	3651
PRDM4	3648
RAB7A	3642
USP2	3633
LAMA4	3629
PDK2	3619
CDC14A	3612
NDEL1	3609
PRKG2	3595
PLXND1	3583
ICMT	3582
HTR7	3581
IQGAP1	3578
MTA3	3560
SMURF1	3557
ZFYVE9	3550
ACTG1	3525
CCR3	3523
PSMD10	3520
JAG2	3516
SH2D2A	3512
RPS6	3469
PSMA5	3448
AMIGO2	3445
POLR2F	3439
NRP1	3435
MECOM	3429
FNBP1L	3416
NCK2	3415
ADCY6	3410
RAG1	3406
HSP90AB1	3401
PLD1	3384
DUSP8	3382
RPS6KB1	3360
CREB1	3358
PPP2CA	3353
MAD1L1	3350
PPP2R5E	3349
DLG4	3329
OSBPL11	3318
DLG3	3317
PRKACB	3303
PPARD	3292
LAMC1	3285
ADRA2C	3268
NHS	3267
MCAM	3243
GNG12	3240
STARD8	3239
CRK	3232
BEX3	3223
ARRB1	3206
SHOC2	3201
CBX6	3181
SKI	3178
FLOT1	3165
RACK1	3159
ABCG8	3158
VPS35	3135
TNKS2	3134
MEF2D	3127
MCF2L	3124
TOR1AIP1	3113
IFT172	3109
RASGRF2	3099
PDGFRB	3093
GTF2F2	3084
ARHGEF9	3079
RARA	3069
MAPK8	3067
PSMA3	3043
ATP6V0B	3037
RPS27	3034
GRB10	3025
CLIP3	3023
LPAR6	2983
HSP90AA1	2976
MMP9	2968
ROCK2	2967
CAB39L	2943
C5AR2	2938
PRKAR1B	2933
HDAC8	2917
UBE2D3	2914
DTX4	2871
ARHGAP22	2832
VAV2	2828
FYN	2820
PPID	2819
H2BC11	2796
BCAP31	2794
NRIP1	2792
PDE4D	2778
RAB6A	2777
POLR2C	2776
RBMX	2768
GLP2R	2765
ELK1	2757
NEDD4	2753
STAT3	2744
NLN	2713
CBX8	2704
ACKR2	2703
NCK1	2702
FZD6	2692
PRMT1	2679
CNOT6L	2677
PTCH1	2670
MDM2	2666
SPOP	2664
CTTN	2642
CKAP4	2630
MYL6	2625
TGIF1	2603
PAK4	2593
GPER1	2579
CAMK2B	2578
ZFYVE16	2573
UBC	2572
SLC38A9	2565
CUL5	2551
ADCY4	2528
FKBP4	2519
SPRED2	2513
PDE4A	2503
PIK3C3	2499
PAK2	2496
RHEB	2463
ARHGEF28	2454
TRIB1	2444
STX5	2431
LAMB1	2429
IL1RAP	2426
C5AR1	2424
TXNL1	2422
DYNC1LI1	2403
FASLG	2399
NSL1	2374
UHMK1	2359
LEMD3	2357
PKN2	2353
EBAG9	2351
MOV10	2343
INHBB	2331
ZNF217	2330
SUZ12	2329
ARHGAP21	2318
RASA1	2313
ACVR2A	2306
CLASP2	2290
ATP6V0C	2287
TMED5	2277
ARHGAP12	2276
PORCN	2271
JAK2	2269
GOLGA7	2266
CDC73	2260
PSMD8	2211
CTNNBIP1	2207
RSPO3	2205
ARHGAP10	2196
PSMD14	2194
DUSP6	2178
ARHGAP35	2168
ATF2	2149
PLIN3	2144
ACTR2	2139
MYH11	2133
NUP133	2121
CSNK1E	2117
PSMA4	2112
STEAP3	2104
RNF41	2098
PHB	2089
MIB2	2082
ACBD5	2080
RALGAPA1	2073
PLCG1	2063
REST	2059
GAS8	2043
RHOA	2032
RDH13	2023
GNA12	2021
LAMC2	2016
MAP3K7	2009
VPS26A	2007
CPNE8	1991
PTGES3	1962
CDC14B	1949
NR1H3	1948
PIK3R1	1940
OS9	1939
ERBIN	1938
PRKAG1	1934
CCT6A	1924
PSMB4	1921
PDE6D	1919
AKAP13	1914
ITGB3	1908
HDAC2	1907
PHC3	1906
SEL1L	1903
ID2	1901
PPP3R1	1893
HNRNPC	1874
PSME3	1870
ST3GAL4	1859
DUSP7	1850
SOX13	1844
PSMD13	1835
NCBP1	1828
NOS3	1827
VAPB	1817
PTPN11	1777
PICALM	1766
RAC1	1751
CAV1	1740
APH1B	1738
OCRL	1733
KCTD3	1730
CHD1	1727
IL2RA	1707
MYLIP	1702
CYFIP2	1697
RHOQ	1686
H3-3A	1684
CDK4	1682
CENPQ	1655
POLR2G	1641
ESR1	1632
IFT88	1631
MOB1A	1619
JAK1	1614
BCL9L	1610
LFNG	1602
MAPKAPK5	1601
HDAC5	1579
GPR18	1577
IFT57	1576
PIK3CB	1574
USP8	1564
ABI1	1553
MAPRE1	1548
PSME1	1537
SKP1	1522
RICTOR	1519
EPN1	1518
KHDRBS1	1516
PDGFRA	1511
MAP2K5	1505
CTBP2	1504
DYNC1LI2	1502
YWHAG	1463
YWHAB	1461
FNTA	1452
PAK6	1445
CTSD	1442
CLIP1	1429
ATF1	1400
AGO3	1396
OFD1	1386
MOSPD2	1379
APC	1359
DHRS4	1347
IFT52	1345
EIF4E	1341
SUFU	1339
XCR1	1316
SEPTIN7	1315
MYL12B	1306
AP2S1	1304
FASN	1301
PTPN2	1300
PDE1C	1294
CCDC88A	1277
YWHAZ	1272
STUB1	1269
RUVBL1	1258
CCT7	1246
RFNG	1241
PRKAA1	1238
CLTC	1234
WIPF1	1228
MAPK11	1224
ARF6	1207
RBBP5	1205
PEBP1	1196
TGFB1	1195
PIP4K2B	1184
ARHGAP32	1176
KANK1	1164
AKT1S1	1161
STIP1	1148
DYNC1H1	1136
PPP2R5C	1128
SMAD4	1118
HDAC9	1094
KDM3A	1092
CNR1	1087
SMURF2	1060
PPP3CB	1050
NMU	1047
B9D2	1036
RALB	1034
TAOK1	1024
CDC42	1019
NCOA2	1018
TBXA2R	993
ARPC5	990
PDE11A	979
RGS5	969
ELMO1	951
TNF	897
GPR17	890
FURIN	885
MXD4	884
PSMA6	883
RASGRP3	878
SUCNR1	870
CYSLTR2	866
DNM3	864
GNB3	853
RPS6KA2	831
KREMEN1	824
WDR35	821
BMPR1B	801
VAV3	765
ALDH1A1	762
UCN	754
ARHGAP23	753
PLCB1	740
VIP	735
LAMA5	732
FAM13B	725
BRK1	703
NCBP2	687
PTPN12	667
CCR10	664
TMOD3	640
RAP1GDS1	631
TMEM87A	630
ARHGEF7	625
CXXC4	612
EIF4B	607
TRIM33	603
ABR	601
PPP1R12A	592
TRPC3	590
PKP4	588
GZMB	573
H2AJ	558
PAQR3	544
PSMD1	535
RSPO2	491
CCT2	490
CHD3	479
CCNT2	473
CYLD	465
GNAI2	453
RAP1A	451
RASA2	442
WDR11	440
SCFD1	439
ARHGDIA	438
RGS11	432
F2RL3	428
EEF2K	402
RBBP6	399
ARAP3	388
BIRC3	377
RIPK1	374
HNRNPA1	369
TERT	365
APH1A	346
ARHGEF11	339
IQCE	338
PTK6	337
SCAI	327
VPS29	312
AGO1	309
SH2B1	307
ARHGAP18	296
DUSP10	275
PIP5K1C	248
ATN1	237
SEMA4F	190
CAB39	186
CALM1	172
ARTN	159
LAMA3	152
PPP3CC	146
STAG1	144
TCIRG1	127
SRC	116
CYP26B1	101
GNAS	100
LAMTOR2	96
BAX	87
BTRC	85
LAMTOR3	84
CEP97	82
ECT2	80
KIF2A	78
UBA52	75
PLPPR2	69
ITGB3BP	55
SQSTM1	49
PSMB7	43
SYNGAP1	37
FGF7	26
TAB3	24
DGKE	19
RNF20	-17
YBX1	-40
PSMB6	-57
NEURL1	-62
DKK2	-63
SNAP23	-67
NDUFS3	-76
PTH2R	-87
LAMTOR5	-90
ELF3	-109
ABCA1	-128
SENP1	-174
BRAP	-182
SOS2	-191
HDAC11	-198
CXCR2	-199
PSMC3	-201
PSMB9	-203
PLD2	-216
PTPRO	-221
LRRK2	-246
NEURL1B	-256
PSMB1	-262
RAP1B	-293
OTULIN	-308
GRAP	-309
RPS6KA5	-310
RRAGD	-315
OPRD1	-320
GABBR1	-330
PREX1	-332
PLAT	-333
PSMD12	-334
PDE5A	-357
PDPK1	-364
PPP2R1A	-370
NUP107	-374
IL33	-378
CBL	-382
PPP1R12B	-386
KLC4	-417
USP9X	-419
KIT	-425
CETP	-442
PSME4	-458
EPS15	-468
PSMA1	-487
SNX3	-504
ITSN2	-516
CSNK2A1	-520
TGIF2	-532
ARPC3	-538
AKT1	-542
XPO1	-557
GFOD1	-579
GOLGA3	-605
MED1	-607
MYH14	-618
POLR2J	-622
FADD	-624
MAPK3	-640
DVL2	-652
PRKAB2	-655
CX3CR1	-663
RALGDS	-671
PDHX	-675
DNM1	-701
SPEN	-707
LETM1	-708
PSMC6	-713
TAS2R14	-728
GRIN2D	-736
TRA2B	-738
CASP9	-744
PLEKHG5	-746
WIF1	-763
GPSM2	-764
PSMD5	-770
SP1	-773
KTN1	-777
CCR5	-784
POLR2I	-790
CCP110	-805
SGO2	-810
NOTCH1	-829
SH3GL1	-830
MAML1	-851
FBXW7	-853
RANBP9	-858
MBD3	-877
FPR3	-880
PRKAG2	-889
CDC37	-893
CASP3	-894
ADGRE3	-901
LYN	-973
OPRM1	-980
MOB1B	-981
CXCR1	-985
DGKQ	-994
CHD8	-1000
FLT3LG	-1012
VEGFB	-1014
DOCK8	-1016
PAFAH1B1	-1031
RND2	-1044
RGS17	-1046
CHUK	-1047
GIT1	-1058
EVL	-1068
AMER1	-1073
ARHGAP17	-1076
DVL3	-1096
ZNF512B	-1105
PRKACA	-1109
ACTR3	-1117
THBS3	-1130
POLR2B	-1143
RAPGEF1	-1145
TSC1	-1151
RASAL1	-1161
AAMP	-1162
KLC1	-1165
NISCH	-1176
CLASP1	-1213
CPT1A	-1222
SOS1	-1232
EMC3	-1237
PSMB8	-1241
H2BC21	-1250
FST	-1251
APBB1IP	-1256
TLE3	-1261
KHDRBS3	-1288
PIN1	-1290
CUL3	-1291
TAX1BP1	-1293
HMOX2	-1302
POLR2E	-1310
CCL28	-1330
MTR	-1332
MKNK1	-1371
RAPGEF3	-1376
POFUT1	-1389
PTPN1	-1390
ABL1	-1394
TRRAP	-1395
FAM13A	-1405
ST3GAL6	-1407
SEH1L	-1420
DERL2	-1432
ABHD17B	-1433
LRRC41	-1436
DUSP16	-1439
SNW1	-1443
STMN1	-1446
NFKB1	-1447
ATP6V1C2	-1450
CCR6	-1455
PPM1A	-1471
ABHD12	-1475
ANKFY1	-1491
TRAK2	-1492
KLB	-1493
ARHGEF26	-1497
PTCH2	-1512
PROKR2	-1514
MIS12	-1526
SMAD2	-1532
NR1H2	-1545
RRAS2	-1552
MAPKAPK2	-1563
CUL1	-1579
CAMKK1	-1591
OXTR	-1598
FKBP1A	-1601
PML	-1609
NSMAF	-1633
UCHL5	-1640
ANKLE2	-1645
SMPD2	-1649
SPTBN4	-1668
KIF14	-1692
MAMLD1	-1707
WDR91	-1710
TRAK1	-1718
FAF2	-1721
FOXO3	-1726
ADD3	-1731
PIK3AP1	-1747
TIAL1	-1757
CBX4	-1763
SCMH1	-1774
SFPQ	-1782
LEPR	-1788
NEDD8	-1797
CBX2	-1812
EFCAB7	-1818
ARPC2	-1824
PDE1B	-1839
RAPGEF2	-1866
CCRL2	-1873
MAP3K11	-1884
MAML3	-1887
RBCK1	-1902
IFT140	-1916
RHOT1	-1919
NELFB	-1922
PKN1	-1927
GNB2	-1970
RPTOR	-1976
ADGRE1	-1987
RSPO4	-1993
MC1R	-2005
TRIP10	-2013
ACTC1	-2031
AVPR2	-2033
PSMC2	-2035
LBR	-2042
TPM3	-2062
SKA2	-2063
E2F5	-2078
THBS2	-2085
RRAGB	-2094
POLR2A	-2097
ABCD3	-2098
PYGO2	-2118
ANLN	-2122
CD28	-2125
CDKN1B	-2126
MPP7	-2144
PDHB	-2152
ZWILCH	-2178
CPT1B	-2186
GNAQ	-2199
SMARCA4	-2206
SNAI2	-2212
PHLPP1	-2213
GPBAR1	-2216
ROCK1	-2243
GNB1	-2252
IHH	-2254
GLI1	-2256
ACVR2B	-2257
VCP	-2260
H2AZ1	-2265
MACO1	-2269
PPP5C	-2289
BDNF	-2292
AP2B1	-2296
PHIP	-2300
BRAF	-2312
ABHD17A	-2316
TTC21B	-2320
GSK3B	-2330
ATP6AP1	-2343
PSMB10	-2349
PSMC1	-2353
FNTB	-2364
AP2M1	-2365
PSMB3	-2369
PIP5K1A	-2388
POLR2D	-2389
NF2	-2396
LGR6	-2406
RING1	-2436
TLE5	-2437
BDKRB1	-2441
MAF1	-2442
PSPN	-2456
CENPP	-2476
TAGAP	-2488
FMNL2	-2490
NCOR2	-2498
PSMD6	-2501
MADD	-2505
DLD	-2508
RAD21	-2511
DNMBP	-2518
BAG4	-2519
ARHGEF2	-2527
PLCB3	-2529
RBX1	-2533
TCF12	-2539
H2BC12	-2546
KL	-2553
TRAF1	-2561
KAT2A	-2565
PIP4K2C	-2567
WNT1	-2568
AATF	-2588
VRK2	-2590
MAPKAP1	-2591
GRK3	-2598
NTSR1	-2617
SOCS1	-2632
PSMA7	-2633
FER	-2635
ARHGAP15	-2644
CAPZB	-2647
UBB	-2665
NUP160	-2679
PSEN2	-2704
AP2A2	-2709
GNG5	-2767
POLR2H	-2768
KDM1B	-2798
RDH10	-2807
HEBP1	-2809
EED	-2827
NLK	-2830
P2RY11	-2831
PROK2	-2837
LAMTOR4	-2851
NTRK3	-2864
FUZ	-2874
PBX1	-2883
VIPR1	-2887
DHRS3	-2894
WDR19	-2914
SMC1A	-2919
GPR84	-2948
HNRNPF	-2965
GABRG2	-2970
ADRA2B	-3002
EEPD1	-3010
RXRA	-3018
ARPC1A	-3033
MMP2	-3039
PRICKLE1	-3051
KDM1A	-3059
TNFSF10	-3072
GAB2	-3076
S100A9	-3080
TLE4	-3095
ADCY3	-3102
STK4	-3112
MTA1	-3119
WIPF2	-3140
WASF1	-3160
TNRC6C	-3185
KMT2D	-3199
CMKLR1	-3201
NR5A2	-3205
ERBB3	-3215
GNAO1	-3219
ADGRE5	-3220
CDC42SE2	-3223
MTOR	-3231
RBPJ	-3233
RNF146	-3239
PTPRJ	-3255
RAB4B	-3275
CCDC115	-3281
ATP6V0A2	-3286
S100A8	-3296
SPTBN1	-3307
CENPA	-3325
PSEN1	-3333
USP34	-3340
KCTD13	-3352
ALS2	-3361
YY1	-3364
SCRIB	-3372
ECE1	-3377
PXN	-3380
RGS19	-3417
GRIN2B	-3420
NUMB	-3434
TSC2	-3442
SAMM50	-3450
EP300	-3453
PSMD4	-3492
TRIM27	-3499
LIMK2	-3521
GRK5	-3523
STRADB	-3530
FGFR4	-3538
USP15	-3542
ATP6V0D1	-3562
SCUBE2	-3581
SIN3A	-3595
NEDD4L	-3596
MYL9	-3598
TAB1	-3608
XK	-3619
AKT2	-3639
PMF1	-3663
ARHGAP11A	-3681
EMD	-3686
IL17RD	-3688
NUDC	-3690
FAS	-3692
MAP2K1	-3701
MTA2	-3710
GTF2F1	-3713
IL2RB	-3724
MAD2L1	-3735
PSMB2	-3751
PTN	-3757
GRM2	-3776
MCF2	-3785
AR	-3789
NUP98	-3797
RASA3	-3798
DOK1	-3803
ARHGEF10L	-3806
MEMO1	-3829
PPP2R5D	-3841
MAPK7	-3865
H2BC15	-3870
SPC25	-3880
HDAC7	-3881
RCE1	-3893
AKAP12	-3911
EIF4G1	-3934
FLNA	-3946
FZD2	-3962
RGR	-3996
NUF2	-3997
NUP37	-3999
WASF2	-4010
DIAPH2	-4016
IRAK4	-4019
LAMTOR1	-4068
DTX1	-4076
ARHGEF6	-4080
KDM4A	-4115
NCKIPSD	-4119
OPRL1	-4132
IGF1R	-4135
PIK3CG	-4137
UBE2M	-4139
SHC2	-4143
CSNK2B	-4147
HNRNPM	-4165
KIF5A	-4174
PTAFR	-4179
RALBP1	-4189
LIN7B	-4199
ARHGEF5	-4201
ARHGAP1	-4204
TAOK3	-4213
TRADD	-4252
RHOH	-4253
ITSN1	-4254
P4HB	-4269
RTN4	-4278
DYNLL2	-4285
FGF9	-4287
STK38	-4301
MYO9B	-4302
RRAGC	-4309
SLC1A5	-4325
NCF2	-4329
DLGAP5	-4338
THEM4	-4340
PIK3R2	-4348
IL6R	-4409
ERCC6L	-4419
ARHGAP26	-4421
RAF1	-4427
ESYT1	-4481
MGLL	-4487
PTBP1	-4504
RAB9B	-4556
KPNA2	-4569
AGO4	-4597
BUB3	-4599
MAPK12	-4620
PLEKHG4B	-4640
HDAC1	-4644
CBY1	-4661
PSMC5	-4664
RGS18	-4668
CFL1	-4675
PDE1A	-4687
CXCR6	-4691
RGL2	-4697
ADAP1	-4699
RAB9A	-4704
MAPK13	-4730
GNA15	-4736
RUNX3	-4741
SPINT2	-4742
AGO2	-4744
KSR1	-4748
FPR1	-4753
ATP6V1G2	-4759
SH2B2	-4766
ARPC4	-4772
TLN1	-4792
PPP2R5A	-4796
ARAP1	-4800
ZRANB1	-4832
NCOR1	-4871
KAT2B	-4874
CDK1	-4876
IQGAP2	-4882
ELMO2	-4908
PELP1	-4910
OPHN1	-4931
EFHD2	-4953
CDK9	-4957
GABRB3	-4959
H2AZ2	-4971
CENPC	-4972
FSTL3	-4983
CENPU	-4987
SRRM1	-4996
PARP1	-5015
PAK1	-5016
WNT9B	-5029
VHL	-5034
GATAD2B	-5061
PSMD7	-5071
DDRGK1	-5072
S1PR4	-5075
PTGER3	-5087
PLEKHG3	-5093
TMPO	-5097
ST3GAL3	-5106
KNL1	-5115
MAP2K2	-5121
HNRNPH1	-5126
KDM4C	-5130
POU2F1	-5137
IKBKB	-5150
SMC3	-5155
CCR4	-5162
BCL2L11	-5164
TBP	-5182
VCL	-5201
ADORA2A	-5203
ARAF	-5207
SLITRK5	-5220
STRADA	-5249
CHEK1	-5253
USF2	-5271
CXCL5	-5303
TRAF2	-5316
KIF18A	-5321
JAK3	-5328
MAPK14	-5334
YWHAH	-5336
POMC	-5345
HGF	-5346
FGF17	-5348
XCL1	-5360
ADCY5	-5366
MEN1	-5385
CDH1	-5398
CSK	-5409
CKAP5	-5414
ATP6V0E2	-5437
CREBBP	-5451
HHIP	-5454
PDK1	-5456
STAT6	-5470
CENPN	-5519
CENPL	-5522
TRAF6	-5526
PPP1CA	-5527
DTX2	-5528
PSMD2	-5529
TLE2	-5531
CXCR3	-5541
RASGRP1	-5552
PDE4C	-5571
BUB1B	-5578
DDX39B	-5594
CAMKK2	-5597
SHKBP1	-5620
MTMR1	-5621
CENPK	-5623
FRAT2	-5639
RAC3	-5641
CRKL	-5670
NDC80	-5671
ARHGEF18	-5672
PSMD3	-5686
NCOA1	-5688
RBBP4	-5692
ADM	-5713
RBBP7	-5724
XCL2	-5735
NET1	-5741
GPS1	-5744
ARHGDIB	-5760
ADCY7	-5766
ARHGAP9	-5772
MAPK1	-5806
WDR81	-5810
TNRC6B	-5822
STAT5B	-5823
HDAC3	-5834
EDNRB	-5840
KLC3	-5841
ARL2	-5844
ACTN1	-5854
FGD4	-5892
NUP43	-5897
GIT2	-5920
PSMD11	-5926
GSK3A	-5928
CRHBP	-5933
CENPE	-5949
PAG1	-5972
RBL1	-5989
RXRB	-5999
FFAR4	-6003
EIF4EBP1	-6030
PSMF1	-6034
BIRC5	-6037
CSNK1G2	-6049
NPHP4	-6052
CDK8	-6062
BUB1	-6067
TUBA1B	-6081
SIRT6	-6084
IRAK1	-6085
WDR6	-6136
SAA1	-6143
DIAPH3	-6150
LPAR2	-6167
MYB	-6176
LEO1	-6179
BASP1	-6183
AXIN1	-6195
RNF31	-6197
EPS15L1	-6251
MYD88	-6255
HGS	-6259
BTC	-6269
TFDP2	-6274
DEPDC1B	-6293
NSFL1C	-6300
PLCG2	-6329
WHAMM	-6358
RHOT2	-6371
MARK3	-6376
IFT122	-6378
TCF7	-6382
TACR1	-6393
PSMD9	-6396
GRB2	-6402
WNT10B	-6405
PPARG	-6410
CCR2	-6425
KIF2C	-6434
ARPC1B	-6441
NCKAP1L	-6446
LRIG1	-6492
NCSTN	-6510
GNB5	-6530
BCR	-6532
RHOG	-6540
NBEA	-6541
KLHL12	-6549
ALDH8A1	-6551
GPNMB	-6573
EGFR	-6577
CTBP1	-6595
HRH4	-6601
C5	-6624
ACTB	-6627
MFN2	-6631
HDAC4	-6643
MYH9	-6652
ARHGEF37	-6659
ARHGAP24	-6668
PLTP	-6684
AGTR1	-6687
DIAPH1	-6695
ASH2L	-6711
PIP4K2A	-6716
PHC2	-6718
PLEKHG6	-6721
CYBB	-6738
SYK	-6752
CENPF	-6764
ZW10	-6777
SPPL2B	-6785
ARAP2	-6811
CENPH	-6827
VRK3	-6831
ANGPT1	-6849
ARHGAP27	-6858
FPR2	-6863
MRTFA	-6866
PIP5K1B	-6878
SH3KBP1	-6879
WASF3	-6883
BCL2L1	-6885
IL2RG	-6896
RDH16	-6901
PDE3A	-6907
CCNK	-6916
PPP2R5B	-6921
RANGAP1	-6931
FGFBP3	-6956
TP53	-6976
NRG2	-6978
DOCK11	-6985
PSMC4	-6992
TLR9	-7023
MAPKAPK3	-7027
CSF2RB	-7034
KCTD6	-7045
GPR132	-7048
STK10	-7051
MKRN1	-7065
LPAR5	-7066
RCOR1	-7068
ZDHHC7	-7119
GPR150	-7120
EGF	-7122
TYK2	-7127
IL5RA	-7131
MFNG	-7140
RDH14	-7146
OXER1	-7150
DGKD	-7155
PIK3CD	-7175
ARHGAP19	-7188
RPS6KB2	-7210
DAAM1	-7216
SOX6	-7232
ACVR1B	-7243
USP4	-7244
SHARPIN	-7254
GPSM3	-7255
SPTA1	-7256
LYL1	-7257
DGKZ	-7264
HDAC6	-7266
NDE1	-7274
SPTBN2	-7281
F11R	-7282
FCER2	-7290
E2F3	-7342
SGO1	-7343
CXCL1	-7357
CDK2	-7359
ALDH3A2	-7364
PRKCB	-7370
CXCL10	-7374
RCC2	-7387
KDM4B	-7401
ACKR3	-7426
PTENP1	-7457
FZD4	-7490
RGS22	-7504
MTMR4	-7520
S1PR5	-7527
PHLPP2	-7541
PFN1	-7552
FMNL1	-7566
ARFGAP2	-7576
INSR	-7587
PTGER4	-7594
P2RY13	-7599
MTX1	-7612
KAT5	-7619
PGRMC2	-7628
IQGAP3	-7645
CXCL11	-7653
EZH2	-7660
GMIP	-7670
ARHGEF16	-7693
DNM2	-7699
NFKBIA	-7730
GNRH1	-7739
USP7	-7742
DSN1	-7750
BTK	-7776
DOCK2	-7783
PLEKHG4	-7791
HDAC10	-7794
RAC2	-7811
SREBF1	-7815
PRC1	-7835
DRD4	-7852
PRR5	-7858
TEC	-7871
PTPRA	-7886
TRIB3	-7900
CFLAR	-7909
GGA3	-7913
TEX2	-7918
CIT	-7921
PIK3R5	-7927
DHRS9	-7942
HPN	-7950
EDN1	-7957
MLST8	-7970
IKZF1	-7975
CPSF7	-7979
ATP6V0A1	-7984
CCDC88C	-7987
PRKCQ	-7988
GATAD2A	-7991
RGS14	-7994
USF1	-8004
TPH1	-8018
AP2A1	-8034
GNG7	-8041
RACGAP1	-8076
OMG	-8102
STAT5A	-8110
MKS1	-8115
TFRC	-8123
ULK3	-8125
ARHGEF1	-8149
RHPN1	-8154
ZAP70	-8157
ARHGAP30	-8180
MLNR	-8185
GRK6	-8186
RET	-8214
LMNB1	-8263
CAMK2G	-8272
PPBP	-8273
STBD1	-8283
IKBKG	-8285
ARHGAP8	-8333
ERBB4	-8340
RASGRP4	-8347
TFDP1	-8357
AKR1C3	-8358
PDE10A	-8369
PTGIR	-8371
PDE7A	-8402
FNBP1	-8406
CXCL6	-8410
ATP2A3	-8416
USP21	-8421
AMH	-8433
CARM1	-8442
KNTC1	-8444
PCK1	-8455
STAM	-8457
CYBA	-8481
DEF6	-8484
SYVN1	-8491
FGD3	-8492
HINT2	-8498
PCP2	-8515
NCF1	-8544
CENPO	-8559
PRKCD	-8561
MIR25	-8562
CNKSR1	-8569
STK11	-8570
PLPPR3	-8572
PDE6A	-8573
KREMEN2	-8582
CASP8	-8586
NMB	-8610
WDR83	-8626
CXCR4	-8632
CENPI	-8637
STOM	-8639
PDHA1	-8646
COL9A2	-8654
RASAL3	-8656
ACVR1C	-8657
ARHGAP25	-8666
DAGLB	-8671
VAV1	-8673
CCND3	-8691
TAS2R4	-8726
TJP2	-8738
OTUD3	-8741
PTK2B	-8749
PRDM1	-8755
GFAP	-8756
RANBP10	-8767
RPS6KA1	-8768
AAAS	-8812
GRK2	-8813
NUP85	-8821
PLPPR4	-8838
ZWINT	-8848
FES	-8852
CDC20	-8856
NOXA1	-8871
WAS	-8884
PLCB2	-8885
NMUR1	-8888
TAS2R20	-8901
FLOT2	-8924
CASP2	-8927
PRKAB1	-8928
ARRB2	-8930
WWOX	-8940
H2BU1	-8956
MYO19	-8959
UBXN11	-8976
DGKA	-8986
CXCR5	-9002
SH3BP1	-9006
GPS2	-9052
PTPN7	-9053
PTGER2	-9093
PPP1R14A	-9094
ARHGAP4	-9098
CDC25C	-9107
H2BC9	-9109
ARHGAP20	-9118
SPTB	-9120
TAS1R3	-9127
PAK3	-9138
F3	-9139
CENPM	-9144
GPR27	-9149
RHOF	-9155
HTR2A	-9171
FRS3	-9174
P2RY2	-9186
RXFP2	-9193
PTPN18	-9198
LAMA1	-9199
MST1	-9219
KBTBD7	-9246
GRAP2	-9252
PTPN6	-9253
ARHGAP6	-9266
H2AC18	-9274
LTB4R	-9291
GHRL	-9304
CD19	-9309
FOXO4	-9317
C3AR1	-9327
SPC24	-9341
NRG1	-9349
ADRB2	-9350
CENPT	-9354
TLE1	-9369
RASGRP2	-9374
MMP3	-9381
PDE8B	-9404
HRH2	-9406
ARHGAP33	-9417
NCF4	-9419
RNF43	-9471
FGF23	-9480
PRKAR2B	-9494
LCK	-9505
SOST	-9512
CCL23	-9515
KEL	-9517
CXCL9	-9519
DOCK3	-9527
CCL5	-9532
NRG4	-9542
ARHGEF4	-9547
CNR2	-9562
PLK1	-9566
RDH5	-9588
FGD2	-9609
TACC3	-9610
CDCA8	-9629
PDE3B	-9630
NTRK1	-9635
CCNE1	-9640
SKA1	-9647
NTRK2	-9657
GATA3	-9671
VEGFD	-9684
UTS2B	-9700
CASP10	-9713
AURKB	-9728
ACKR1	-9743
PTCRA	-9759
RSPO1	-9760
ESR2	-9765
LAT	-9770
ACKR4	-9797
FKBP5	-9818
ARHGAP11B	-9825
LTB4R2	-9833
CCR7	-9837
E2F4	-9869
INCENP	-9919
ADRB1	-9949
COL4A4	-10003
HTR2B	-10036
EPOR	-10043
P2RY12	-10050
DGKG	-10064
APOD	-10121
RASGEF1A	-10127
GPR35	-10152
PDE6B	-10174
H2AC20	-10202
PLIN1	-10207
GNAL	-10209
TSHR	-10225
COL9A1	-10245
ADCY10	-10247
MYCN	-10278
GPAM	-10283
WIPF3	-10297
CDK5R1	-10308
GPR55	-10319
E2F1	-10324
PF4	-10333
ARHGEF39	-10338
FRAT1	-10355
PARD6B	-10359
SSTR1	-10363
CCL13	-10368
PIK3R6	-10409
PTGDR2	-10414
PDK4	-10433
COL4A3	-10446
CASR	-10472
PROK1	-10492
GNRHR2	-10499
CGN	-10523
SCTR	-10537
FLT3	-10551
SH3GL3	-10557
ADORA2B	-10561
PPP1R1B	-10563
LEP	-10602
ITGA2B	-10608
ASCL1	-10622
HCAR1	-10706
PENK	-10712
P2RY14	-10754
WNT10A	-10763
PTGDR	-10774
VIPR2	-10779
CSF2RA	-10780
THBS4	-10781
IGF1	-10790
IRS2	-10805
CCL19	-10806
PCSK6	-10808
GNAZ	-10817
TFF3	-10858
NPY1R	-10863
SFRP1	-10870
NPY5R	-10879
CHRDL1	-10883
ADORA3	-10884
PTGFR	-10888
RGS6	-10893
COL4A5	-10902
MUC20	-10913
HCRTR2	-10930
LAMA2	-10937
C3	-10942
FGF10	-10944
GPC5	-10955
ADH1C	-10958
WNT11	-10979
CCL21	-10989
SFRP2	-10998

---

tRNA processing in the mitochondrion

tRNA processing in the mitochondrion

	1449
set	tRNA processing in the mitochondrion
setSize	26
pANOVA	6.3e-12
s.dist	0.778
p.adjustANOVA	1.99e-10

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MT-RNR2	9176
MT-RNR1	9091
MT-CO2	8974
MT-TC	8968
MT-ND1	8947
MT-CO1	8940
MT-CO3	8846
MT-TA	8836
MT-CYB	8747
MT-TY	8718
MT-ND2	8670
MT-TS1	8590
MT-ATP6	8433
MT-ND3	8218
MT-TP	8217
MT-ND5	8211
MT-TN	8077
MT-ND4	7970
MT-ND6	7914
MT-ND4L	7683

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MT-RNR2	9176
MT-RNR1	9091
MT-CO2	8974
MT-TC	8968
MT-ND1	8947
MT-CO1	8940
MT-CO3	8846
MT-TA	8836
MT-CYB	8747
MT-TY	8718
MT-ND2	8670
MT-TS1	8590
MT-ATP6	8433
MT-ND3	8218
MT-TP	8217
MT-ND5	8211
MT-TN	8077
MT-ND4	7970
MT-ND6	7914
MT-ND4L	7683
PRORP	6612
MT-ATP8	6335
TRMT10C	2282
TRNT1	748
HSD17B10	-1655
ELAC2	-4662

---

Cell Cycle, Mitotic

Cell Cycle, Mitotic

	163
set	Cell Cycle, Mitotic
setSize	503
pANOVA	9.78e-12
s.dist	-0.177
p.adjustANOVA	3.02e-10

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TUBAL3	-10839
TUBG1	-10336
E2F1	-10324
PPP2R3B	-10275
H2AC20	-10202
POLA2	-10057
PKMYT1	-9959
INCENP	-9919
TUBA4A	-9905
E2F4	-9869
NCAPH	-9868
MCM5	-9835
AURKB	-9728
LIG1	-9694
E2F2	-9678
SKA1	-9647
CCNE1	-9640
CDCA8	-9629
FOXM1	-9602
PLK1	-9566

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TUBAL3	-10839
TUBG1	-10336
E2F1	-10324
PPP2R3B	-10275
H2AC20	-10202
POLA2	-10057
PKMYT1	-9959
INCENP	-9919
TUBA4A	-9905
E2F4	-9869
NCAPH	-9868
MCM5	-9835
AURKB	-9728
LIG1	-9694
E2F2	-9678
SKA1	-9647
CCNE1	-9640
CDCA8	-9629
FOXM1	-9602
PLK1	-9566
TUBB1	-9553
CDT1	-9526
MCM10	-9508
PRKAR2B	-9494
ESPL1	-9438
MCM4	-9413
MCM7	-9356
CENPT	-9354
SPC24	-9341
CDC25A	-9316
H2AC18	-9274
KIF20A	-9255
MCM2	-9218
CDC6	-9194
MYBL2	-9180
CENPM	-9144
H2BC9	-9109
CDC25C	-9107
NUP210	-9091
FEN1	-8998
H2BU1	-8956
MCM3	-8945
CDCA5	-8939
KMT5A	-8916
CDK11A	-8911
CDC20	-8856
POLD1	-8854
ZWINT	-8848
NUP85	-8821
AAAS	-8812
CDK11B	-8759
TUBGCP3	-8751
GTSE1	-8696
CCND3	-8691
MAX	-8680
HAUS8	-8640
CENPI	-8637
TK1	-8621
RRM2	-8611
GINS4	-8604
CDC45	-8576
CENPO	-8559
PPME1	-8523
MASTL	-8454
POLE	-8450
KNTC1	-8444
CEP72	-8394
TFDP1	-8357
ORC6	-8295
TUBGCP4	-8276
CDKN2C	-8275
TUBB	-8269
LMNB1	-8263
NCAPH2	-8224
SFI1	-8118
RPA1	-8065
HAUS5	-8036
AURKA	-7985
TUBB2B	-7932
GINS1	-7920
CENPJ	-7919
RFC5	-7869
HAUS2	-7758
DSN1	-7750
CCNB2	-7711
CCNA1	-7689
TPX2	-7672
NUP93	-7651
UBE2C	-7617
NCAPD3	-7607
NCAPG2	-7557
CEP192	-7509
CDC25B	-7508
WEE1	-7491
DHFR	-7420
RCC2	-7387
PRKCB	-7370
KIF23	-7368
CDK2	-7359
SGO1	-7343
E2F3	-7342
ORC1	-7325
NDE1	-7274
PCNA	-7230
CNTRL	-7193
CCNE2	-7189
MCM6	-7098
GINS2	-7046
PSMC4	-6992
TP53	-6976
RANGAP1	-6931
SKP2	-6928
PPP2R5B	-6921
NCAPD2	-6899
CENPH	-6827
ZW10	-6777
CENPF	-6764
CCNA2	-6737
CDKN2D	-6727
ANAPC1	-6719
CCNB1	-6690
SSNA1	-6617
DNA2	-6552
LIN52	-6487
POLD4	-6484
NUP42	-6458
KIF2C	-6434
PSMD9	-6396
NUP214	-6384
FBXO5	-6279
TFDP2	-6274
POM121	-6266
ESCO2	-6252
TYMS	-6202
PLK4	-6092
TUBA1B	-6081
PTTG1	-6071
BUB1	-6067
ANAPC7	-6043
BIRC5	-6037
PSMF1	-6034
RBL1	-5989
POLA1	-5986
CENPE	-5949
VRK1	-5940
PSMD11	-5926
TPR	-5915
NUP43	-5897
FZR1	-5888
TUBB4B	-5873
RFC4	-5863
PCNT	-5838
MAPK1	-5806
PPP2R2D	-5801
ANAPC4	-5798
RAE1	-5771
RBBP4	-5692
PSMD3	-5686
ORC5	-5679
MAU2	-5674
NDC80	-5671
CENPK	-5623
SMC2	-5613
MZT2A	-5611
RFC2	-5605
BUB1B	-5578
PSMD2	-5529
CENPL	-5522
CENPN	-5519
CKAP5	-5414
NUP188	-5399
VPS4A	-5394
KIF18A	-5321
CHMP4B	-5304
NEK2	-5272
NCAPG	-5217
TUBGCP6	-5188
SMC3	-5155
MCM8	-5135
KNL1	-5115
TMPO	-5097
PSMD7	-5071
CENPU	-4987
ANAPC2	-4981
CENPC	-4972
H2AZ2	-4971
CEP131	-4955
CDK1	-4876
ANAPC15	-4852
PPP2R5A	-4796
PRIM1	-4694
LPIN1	-4688
PSMC5	-4664
HDAC1	-4644
CHMP4A	-4624
BUB3	-4599
CHMP7	-4583
ALMS1	-4534
CEP250	-4502
HAUS3	-4444
NUP62	-4426
ERCC6L	-4419
DYNLL2	-4285
HAUS4	-4274
RPA3	-4265
GMNN	-4259
CSNK2B	-4147
CDC16	-4112
DYRK1A	-4055
UBE2I	-4049
RFC3	-4046
FKBPL	-4017
PHF8	-4003
NUP37	-3999
NUF2	-3997
DCTN3	-3989
POLE2	-3978
TUBA1C	-3969
SPC25	-3880
DCTN2	-3876
H2BC15	-3870
PPP2R5D	-3841
NUP98	-3797
CKS1B	-3791
PSMB2	-3751
NUP50	-3737
MAD2L1	-3735
CHMP2A	-3718
CDC7	-3717
NUMA1	-3715
NUDC	-3690
EMD	-3686
CDC23	-3676
PMF1	-3663
TUBGCP2	-3645
CDC27	-3643
POM121C	-3641
AKT2	-3639
ORC3	-3618
ORC2	-3617
OPTN	-3493
PSMD4	-3492
EP300	-3453
CDKN2A	-3397
TUBG2	-3367
CENPA	-3325
CDK7	-3248
HAUS7	-3218
CDK5RAP2	-3191
SIRT2	-3165
KPNB1	-3164
CHMP6	-3163
SMC4	-3151
CEP78	-3127
CABLES1	-3117
TOP2A	-3058
BORA	-3016
NUP155	-3011
CSNK1D	-2925
SMC1A	-2919
RPA2	-2828
NUP160	-2679
LPIN2	-2668
UBB	-2665
POLD3	-2652
PSMA7	-2633
CEP76	-2604
VRK2	-2590
CCND2	-2569
PDS5A	-2557
H2BC12	-2546
EML4	-2544
CTDNEP1	-2534
RBX1	-2533
DBF4	-2525
RAD21	-2511
RFC1	-2507
PSMD6	-2501
NDC1	-2483
CENPP	-2476
POLE3	-2469
NUP54	-2399
PSMB3	-2369
PSMC1	-2353
PSMB10	-2349
GSK3B	-2330
ODF2	-2322
NUP153	-2287
ANAPC16	-2268
H2AZ1	-2265
CC2D1B	-2219
CEP152	-2215
ZWILCH	-2178
RAB8A	-2157
CDKN1B	-2126
PRIM2	-2093
E2F5	-2078
SKA2	-2063
NUP205	-2044
LBR	-2042
PSMC2	-2035
RAB1B	-1935
HAUS1	-1821
ANKLE2	-1645
CEP43	-1637
DCTN1	-1587
CUL1	-1579
NIPBL	-1559
RAN	-1554
MIS12	-1526
HAUS6	-1519
RCC1	-1456
SEH1L	-1420
ABL1	-1394
SDCCAG8	-1294
WAPL	-1277
LEMD2	-1269
H2BC21	-1250
PSMB8	-1241
CLASP1	-1213
LIN37	-1118
PRKACA	-1109
ENSA	-1066
PAFAH1B1	-1031
LYN	-973
ESCO1	-960
UBE2S	-944
CEP57	-881
HMMR	-861
SGO2	-810
CCP110	-805
PSMD5	-770
PSMC6	-713
GOLGA2	-705
MAPK3	-640
CEP164	-602
XPO1	-557
AKT1	-542
CSNK2A1	-520
PSMA1	-487
PSME4	-458
ACTR1A	-418
PPP1R12B	-386
NUP107	-374
PPP2R1A	-370
PSMD12	-334
ANAPC5	-329
PSMB1	-262
PSMB9	-203
PSMC3	-201
LIN9	-185
GORASP1	-139
TUBGCP5	-134
LPIN3	-126
PSMB6	-57
NUP88	1
PSMB7	43
ITGB3BP	55
UBA52	75
KIF2A	78
BTRC	85
SRC	116
STAG1	144
IST1	217
PTK6	337
CEP290	375
ORC4	497
PSMD1	535
H2AJ	558
PPP1R12A	592
ARPP19	837
PSMA6	883
CDK6	894
POLE4	967
TAOK1	1024
B9D2	1036
ANAPC11	1105
PPP2R5C	1128
DYNC1H1	1136
AKAP9	1305
OFD1	1386
NEDD1	1426
CLIP1	1429
SPAST	1435
MZT2B	1457
YWHAG	1463
DYNC1LI2	1502
PCM1	1521
SKP1	1522
NEK7	1527
PSME1	1537
MAPRE1	1548
LCMT1	1651
CENPQ	1655
CDK4	1682
H3-3A	1684
POLD2	1717
CEP70	1720
NUP58	1820
PDS5B	1834
PSMD13	1835
PSME3	1870
TUBB2A	1872
PSMB4	1921
CNEP1R1	1977
PSMA4	2112
CSNK1E	2117
NUP133	2121
PSMD14	2194
PSMD8	2211
RBL2	2227
SET	2242
CDKN1C	2262
JAK2	2269
CLASP2	2290
LEMD3	2357
NSL1	2374
LIN54	2396
DYNC1LI1	2403
FBXL18	2453
UBC	2572
PPP2R2A	2601
CHMP3	2637
TUBA8	2771
H2BC11	2796
HDAC8	2917
MCPH1	2974
HSP90AA1	2976
RPS27	3034
PSMA3	3043
CHMP2B	3333
PPP2R5E	3349
MAD1L1	3350
PPP2CA	3353
CETN2	3356
CEP63	3374
BANF1	3385
CEP135	3387
HSP90AB1	3401
PSMA5	3448
NME7	3474
PSMD10	3520
NDEL1	3609
CDC14A	3612
CCNH	3710
UBE2E1	3718
SEC13	3773
NEK9	3782
MZT1	3819
GORASP2	3884
TUBB6	3913
NUP35	3944
H2AC6	3982
STAG2	4003
RANBP2	4107
TNPO1	4177
PPP1CC	4305
PSMA2	4316
E2F6	4336
BLZF1	4367
AHCTF1	4509
RB1	4514
SUMO1	4538
RPS27A	4555
ANAPC10	4582
YWHAE	4598
SPDL1	4612
GINS3	4771
DYNC1I2	4775
CEP41	4822
NINL	4987
PSME2	5088
MYC	5260
CSNK2A2	5397
MNAT1	5649
H2BC5	5661
RAB2A	5669
H2BC4	5688
PPP2R1B	5744
RAB1A	5784
CDKN2B	5830
PPP1CB	5905
FBXW11	6219
DYNLL1	6259
CDC26	6280
SEM1	6281
USO1	6347
TUBB3	6485
UBE2D1	6535
FBXL7	6637
PPP2CB	7026
PSMB5	7356
LMNA	7480
DYNC1I1	7586
CCND1	7921
AKT3	8339
AJUBA	8365
NEK6	8414
PRKCA	8540
TUBA1A	8594
PHLDA1	8951
CDKN1A	9070
CHMP4C	9159

---

Translation

Translation

	1355
set	Translation
setSize	294
pANOVA	1.79e-11
s.dist	0.228
p.adjustANOVA	5.42e-10

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MT-RNR2	9176
MT-RNR1	9091
EEF1A2	8503
MRPL17	8179
RPSA	7908
RPL9	7848
RPS27L	6864
MTRF1L	6846
SRPRB	6824
GSPT2	6768
MRPS6	6533
SSR3	6502
RPL41	6462
EEF1G	6165
RPS2	6089
EEF1A1P5	6039
RPS9	6020
RPL18A	5926
EIF4A1	5895
EEF1A1	5862

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MT-RNR2	9176
MT-RNR1	9091
EEF1A2	8503
MRPL17	8179
RPSA	7908
RPL9	7848
RPS27L	6864
MTRF1L	6846
SRPRB	6824
GSPT2	6768
MRPS6	6533
SSR3	6502
RPL41	6462
EEF1G	6165
RPS2	6089
EEF1A1P5	6039
RPS9	6020
RPL18A	5926
EIF4A1	5895
EEF1A1	5862
RPS13	5739
RPLP0	5695
RPL24	5693
RPL39L	5631
SSR1	5583
MRPL40	5533
SSR2	5527
RPS3A	5482
RPL36A	5419
EEF2	5402
RPL7	5370
RPL37A	5366
SEC61G	5359
MRPL24	5355
RPL23A	5347
MRPL15	5326
MRPL42	5261
MRPL33	5226
RPL13A	5213
EIF3I	5192
RPL13	5185
RPS16	5179
RPL15	5149
EIF2S1	5134
IARS1	5118
RARS1	5107
MRPS33	5094
RPL4	5091
MRPL30	5090
MRPL54	5080
RPL36AL	5042
RPS11	4999
RPS19	4946
RPL32	4893
RPL39	4878
MRPL51	4868
RPL29	4831
RPL31	4824
RPS10	4796
RPL19	4738
TRAM1	4708
MRPS35	4678
GADD45GIP1	4617
MRPL14	4561
RPS27A	4555
EIF1AX	4546
EEF1D	4542
RPL28	4540
ETF1	4529
MRPL53	4523
RPL18	4499
MRPS36	4496
RPL7A	4483
EEF1B2	4480
RPL3	4426
MRPS28	4408
EIF3E	4400
RPL17	4292
RPS3	4276
RPL27	4270
RPL23	4262
RPL6	4249
RPL35A	4246
RPS18	4239
RPS23	4200
RPL10A	4189
RPS17	4171
RPS5	4154
EIF3L	4150
RPL12	4132
RPS8	4115
SRP9	4066
MRPL27	4056
LARS1	4043
RPL8	4000
MTFMT	3962
RPL14	3947
RPS24	3930
RPL34	3928
SARS1	3890
RPL37	3888
RPS25	3886
RPS7	3878
SEC11A	3858
RPL26	3817
RPL35	3741
RPS12	3713
RPS15A	3668
RPL10	3638
SRP14	3598
RPL38	3564
EIF3G	3561
MRPS18A	3531
RPL36	3513
RPS6	3469
RPS21	3461
EARS2	3422
RPL30	3402
RPS15	3394
EIF2B2	3359
EIF3H	3328
EIF2B3	3316
FAU	3307
MRPL47	3300
RPL22	3284
SRP72	3272
MRPS24	3238
RPL21	3212
IARS2	3179
RPS29	3177
GFM1	3172
MRPL19	3066
RPL5	3062
RPL22L1	3056
RPS27	3034
MRPS18C	3000
GFM2	2992
MRPL48	2954
RPS20	2909
PPA1	2857
MRPL21	2853
EIF3J	2844
EPRS1	2788
MRPL50	2773
RPLP1	2674
SPCS1	2646
RPL27A	2608
SEC61A1	2587
MRPL3	2520
RPS4Y1	2516
EEF1E1	2384
EIF4A2	2349
AURKAIP1	2304
GARS1	2291
AIMP1	2283
CHCHD1	2240
SPCS3	2037
DARS1	2034
RPL11	2004
RPLP2	1969
MRPS7	1885
MRPS21	1818
RPS28	1779
EIF3K	1770
MRPL12	1762
EIF3M	1661
MRPS23	1638
EIF5	1532
RPL26L1	1510
MRPS12	1500
MRPL13	1485
PPA2	1459
MRPS10	1436
EIF3D	1419
NARS2	1351
EIF4E	1341
MTIF2	1335
SEC61B	1331
RARS2	1230
RPS14	1220
MRPS15	1208
MRPL34	1088
KARS1	1073
EIF3C	985
MRPL45	882
MRPL36	764
SRP19	755
EIF4B	607
MRPL1	525
RPN2	429
DAP3	397
MRPS26	378
EIF2S2	367
MRPS14	236
MRPS22	216
SEC61A2	196
MRPL39	148
MRPL44	126
RPS4X	120
UBA52	75
NARS1	10
TRMT112	-6
EIF2S3	-13
MRPS18B	-186
LARS2	-303
MRPS17	-384
MRPS34	-477
MRPL32	-482
EIF3A	-495
MRPL9	-501
MRPS31	-506
FARS2	-511
TARS1	-617
MRPL18	-835
YARS2	-934
MRPL22	-943
EIF4H	-1018
MRPL57	-1043
MTIF3	-1051
MRPL35	-1069
MRPL43	-1249
MRPL52	-1298
N6AMT1	-1444
RPL3L	-1445
MRPL58	-1662
GSPT1	-1686
SRP54	-1688
MRPL46	-1768
QARS1	-1918
MRPL20	-2046
WARS2	-2074
MRPS16	-2195
SPCS2	-2196
TUFM	-2280
YARS1	-2305
MRPL49	-2334
RPN1	-2375
CARS1	-2487
SRP68	-2552
MRPS30	-2560
MRPL23	-2669
MRPL41	-2685
EIF3F	-2691
EIF2B4	-2867
MRPS2	-2982
EIF5B	-3017
AIMP2	-3046
MRPS27	-3229
MRPS11	-3232
MARS2	-3263
AARS1	-3265
SSR4	-3359
EIF4G1	-3934
MRPL11	-4102
DARS2	-4158
FARSB	-4412
DDOST	-4482
MARS1	-4552
MRPL55	-4625
SRPRA	-4669
HARS2	-4692
HARS1	-4838
TSFM	-4918
PABPC1	-5187
PTCD3	-5340
RPS26	-5402
EIF2B1	-5419
MRPS9	-5458
AARS2	-5507
MRPS25	-5642
VARS1	-5665
MRPS5	-5784
MRPL4	-5789
ERAL1	-5843
WARS1	-5944
EIF4EBP1	-6030
MRRF	-6072
MRPL37	-6122
MRPL16	-6306
MRPL10	-6310
MRPL28	-6423
EIF3B	-6895
FARSA	-6960
VARS2	-7245
SARS2	-7278
TARS2	-7311
PARS2	-7373
MRPL2	-7424
OXA1L	-7435
APEH	-8010
EIF2B5	-8026
CARS2	-8790
MRPL38	-8808
SEC11C	-8869

---

Anti-inflammatory response favouring Leishmania parasite infection

Anti-inflammatory response favouring Leishmania parasite infection

	74
set	Anti-inflammatory response favouring Leishmania parasite infection
setSize	179
pANOVA	2.16e-11
s.dist	-0.29
p.adjustANOVA	6.26e-10

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
DPEP1	-10943
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
GNAZ	-10817

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
DPEP1	-10943
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
GNAZ	-10817
IGKV2-28	-10803
IGLV10-54	-10795
IGLV2-18	-10793
VIPR2	-10779
PTGDR	-10774
IGKV5-2	-10765
IGLV5-45	-10764
IGLV1-40	-10748
IGLV1-44	-10737
IGLV3-25	-10735
IGLV3-27	-10722
IGLC1	-10709
IGLV4-69	-10707
IGLV3-21	-10693
IGLV1-36	-10689
IGLV1-47	-10672
IGLV6-57	-10655
IGKV4-1	-10646
IGKV2-30	-10624
IGHV3-23	-10617
IGHV2-5	-10606
IGKV1-17	-10600
IGKV3-11	-10566
ADORA2B	-10561
IGHG3	-10545
SCTR	-10537
IGHG1	-10504
IGLV4-60	-10497
IGKV1-5	-10469
IGLV5-37	-10417
IGHV4-34	-10407
IGHV1-46	-10406
IGLV3-19	-10372
IGKV3-15	-10313
IGKV3-20	-10300
TSHR	-10225
IGKV1D-39	-9965
ADRB1	-9949
IGKV1-12	-9925
IGHV3-11	-9849
IGHV1-2	-9703
IGHV3-48	-9695
IGHV2-70	-9600
PRKAR2B	-9494
IGKV1-16	-9486
CD3G	-9464
HRH2	-9406
ADRB2	-9350
IGKV2D-40	-9270
RXFP2	-9193
IGKC	-9161
GPR27	-9149
PTGER2	-9093
IGHV4-59	-8996
IGKV1D-16	-8851
FGR	-8592
IGHV4-39	-8439
PTGIR	-8371
CD247	-8130
GNG7	-8041
IGLC7	-7752
PTGER4	-7594
DPEP3	-7379
IGHG4	-7204
GPR150	-7120
FCGR3A	-7081
SYK	-6752
MYH9	-6652
DPEP2	-6609
GNB5	-6530
HCK	-6369
PLCG2	-6329
CD163	-5793
ADCY7	-5766
ADM	-5713
ADCY5	-5366
POMC	-5345
RHBDF2	-5338
MAPK14	-5334
ADORA2A	-5203
IGKV2D-28	-3452
ADCY3	-3102
IGHV1-69	-2950
GPR84	-2948
GGT1	-2907
VIPR1	-2887
P2RY11	-2831
GNG5	-2767
GNB1	-2252
GPBAR1	-2216
FCGR1A	-2052
AVPR2	-2033
MC1R	-2005
GNB2	-1970
IGKV1-33	-1353
PRKACA	-1109
LYN	-973
IGKV1-39	-666
PTH2R	-87
GNAS	100
SRC	116
CALM1	172
GNAI2	453
FCGR2A	712
VIP	735
GNB3	853
CYSLTR2	866
FURIN	885
GGT5	1596
PLCG1	2063
ADCY4	2528
GLP2R	2765
IGKV3D-20	2798
FYN	2820
PRKAR1B	2933
GNG12	3240
PRKACB	3303
CREB1	3358
ADCY6	3410
HTR7	3581
GNAI1	3838
AHCYL1	4052
GNAI3	4207
CYSLTR1	4515
ADAM17	5082
PRKAR2A	5114
GNG2	5131
ADCY2	5254
PRKX	5301
ADCY9	5457
CALCRL	5673
GNG10	6094
ITPR1	6224
RAMP1	6260
ADM2	6386
ITPR3	6415
RAMP2	6490
GNG11	6712
GPR176	6898
ITPR2	7099
YES1	7207
PRKAR1A	7315
PTH1R	7363
ADCYAP1R1	7768
PLK2	7799
GNB4	7820
CRH	7897
RAMP3	7993
GIPR	8046
GNGT2	8231
PTHLH	8314
CRHR2	8573
ADCY1	8733
GPR15	8766
CALCR	8812
ADCYAP1	9095
GNG4	9113
IL6	9183
IL10	9201

---

Leishmania parasite growth and survival

Leishmania parasite growth and survival

	624
set	Leishmania parasite growth and survival
setSize	179
pANOVA	2.16e-11
s.dist	-0.29
p.adjustANOVA	6.26e-10

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
DPEP1	-10943
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
GNAZ	-10817

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV8-61	-11000
IGLC2	-10988
IGHV3-13	-10975
IGLV3-1	-10971
IGLV2-14	-10970
IGLC3	-10962
IGLV7-43	-10953
IGLV3-16	-10948
DPEP1	-10943
IGHG2	-10941
IGHV3-30	-10939
IGLV2-8	-10924
IGLV7-46	-10918
IGHV3-33	-10915
IGHV3-7	-10876
IGLV2-11	-10869
IGHV3-53	-10857
IGLV2-23	-10836
IGLV1-51	-10828
GNAZ	-10817
IGKV2-28	-10803
IGLV10-54	-10795
IGLV2-18	-10793
VIPR2	-10779
PTGDR	-10774
IGKV5-2	-10765
IGLV5-45	-10764
IGLV1-40	-10748
IGLV1-44	-10737
IGLV3-25	-10735
IGLV3-27	-10722
IGLC1	-10709
IGLV4-69	-10707
IGLV3-21	-10693
IGLV1-36	-10689
IGLV1-47	-10672
IGLV6-57	-10655
IGKV4-1	-10646
IGKV2-30	-10624
IGHV3-23	-10617
IGHV2-5	-10606
IGKV1-17	-10600
IGKV3-11	-10566
ADORA2B	-10561
IGHG3	-10545
SCTR	-10537
IGHG1	-10504
IGLV4-60	-10497
IGKV1-5	-10469
IGLV5-37	-10417
IGHV4-34	-10407
IGHV1-46	-10406
IGLV3-19	-10372
IGKV3-15	-10313
IGKV3-20	-10300
TSHR	-10225
IGKV1D-39	-9965
ADRB1	-9949
IGKV1-12	-9925
IGHV3-11	-9849
IGHV1-2	-9703
IGHV3-48	-9695
IGHV2-70	-9600
PRKAR2B	-9494
IGKV1-16	-9486
CD3G	-9464
HRH2	-9406
ADRB2	-9350
IGKV2D-40	-9270
RXFP2	-9193
IGKC	-9161
GPR27	-9149
PTGER2	-9093
IGHV4-59	-8996
IGKV1D-16	-8851
FGR	-8592
IGHV4-39	-8439
PTGIR	-8371
CD247	-8130
GNG7	-8041
IGLC7	-7752
PTGER4	-7594
DPEP3	-7379
IGHG4	-7204
GPR150	-7120
FCGR3A	-7081
SYK	-6752
MYH9	-6652
DPEP2	-6609
GNB5	-6530
HCK	-6369
PLCG2	-6329
CD163	-5793
ADCY7	-5766
ADM	-5713
ADCY5	-5366
POMC	-5345
RHBDF2	-5338
MAPK14	-5334
ADORA2A	-5203
IGKV2D-28	-3452
ADCY3	-3102
IGHV1-69	-2950
GPR84	-2948
GGT1	-2907
VIPR1	-2887
P2RY11	-2831
GNG5	-2767
GNB1	-2252
GPBAR1	-2216
FCGR1A	-2052
AVPR2	-2033
MC1R	-2005
GNB2	-1970
IGKV1-33	-1353
PRKACA	-1109
LYN	-973
IGKV1-39	-666
PTH2R	-87
GNAS	100
SRC	116
CALM1	172
GNAI2	453
FCGR2A	712
VIP	735
GNB3	853
CYSLTR2	866
FURIN	885
GGT5	1596
PLCG1	2063
ADCY4	2528
GLP2R	2765
IGKV3D-20	2798
FYN	2820
PRKAR1B	2933
GNG12	3240
PRKACB	3303
CREB1	3358
ADCY6	3410
HTR7	3581
GNAI1	3838
AHCYL1	4052
GNAI3	4207
CYSLTR1	4515
ADAM17	5082
PRKAR2A	5114
GNG2	5131
ADCY2	5254
PRKX	5301
ADCY9	5457
CALCRL	5673
GNG10	6094
ITPR1	6224
RAMP1	6260
ADM2	6386
ITPR3	6415
RAMP2	6490
GNG11	6712
GPR176	6898
ITPR2	7099
YES1	7207
PRKAR1A	7315
PTH1R	7363
ADCYAP1R1	7768
PLK2	7799
GNB4	7820
CRH	7897
RAMP3	7993
GIPR	8046
GNGT2	8231
PTHLH	8314
CRHR2	8573
ADCY1	8733
GPR15	8766
CALCR	8812
ADCYAP1	9095
GNG4	9113
IL6	9183
IL10	9201

---

Here is the session info with all the versions of packages used.

sessionInfo()

## R version 4.2.0 (2022-04-22)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 20.04.4 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.9.0
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.9.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.2.4               GGally_2.1.2               
##  [3] beeswarm_0.4.0              gtools_3.9.2               
##  [5] echarts4r_0.4.3             kableExtra_1.3.4           
##  [7] topconfects_1.8.0           limma_3.48.3               
##  [9] eulerr_6.1.1                mitch_1.4.1                
## [11] MASS_7.3-56                 fgsea_1.18.0               
## [13] gplots_3.1.1                DESeq2_1.32.0              
## [15] SummarizedExperiment_1.22.0 Biobase_2.52.0             
## [17] MatrixGenerics_1.4.3        matrixStats_0.61.0         
## [19] GenomicRanges_1.44.0        GenomeInfoDb_1.28.4        
## [21] IRanges_2.26.0              S4Vectors_0.30.2           
## [23] BiocGenerics_0.38.0         reshape2_1.4.4             
## [25] forcats_0.5.1               stringr_1.4.0              
## [27] dplyr_1.0.8                 purrr_0.3.4                
## [29] readr_2.1.2                 tidyr_1.2.0                
## [31] tibble_3.1.6                ggplot2_3.3.5              
## [33] tidyverse_1.3.1             zoo_1.8-9                  
## 
## loaded via a namespace (and not attached):
##   [1] colorspace_2.0-3       ellipsis_0.3.2         rprojroot_2.0.2       
##   [4] XVector_0.32.0         fs_1.5.2               rstudioapi_0.13       
##   [7] bit64_4.0.5            AnnotationDbi_1.54.1   fansi_1.0.2           
##  [10] lubridate_1.8.0        xml2_1.3.3             splines_4.2.0         
##  [13] cachem_1.0.6           geneplotter_1.70.0     knitr_1.37            
##  [16] jsonlite_1.8.0         broom_0.7.12           annotate_1.70.0       
##  [19] dbplyr_2.1.1           png_0.1-7              shiny_1.7.1           
##  [22] compiler_4.2.0         httr_1.4.2             backports_1.4.1       
##  [25] assertthat_0.2.1       Matrix_1.4-1           fastmap_1.1.0         
##  [28] cli_3.2.0              later_1.3.0            htmltools_0.5.2       
##  [31] tools_4.2.0            gtable_0.3.0           glue_1.6.2            
##  [34] GenomeInfoDbData_1.2.6 fastmatch_1.1-3        Rcpp_1.0.8.2          
##  [37] cellranger_1.1.0       jquerylib_0.1.4        vctrs_0.3.8           
##  [40] Biostrings_2.60.2      svglite_2.1.0          xfun_0.30             
##  [43] rvest_1.0.2            mime_0.12              lifecycle_1.0.1       
##  [46] XML_3.99-0.9           zlibbioc_1.38.0        scales_1.1.1          
##  [49] promises_1.2.0.1       hms_1.1.1              RColorBrewer_1.1-2    
##  [52] yaml_2.3.5             gridExtra_2.3          memoise_2.0.1         
##  [55] sass_0.4.0             reshape_0.8.8          stringi_1.7.6         
##  [58] RSQLite_2.2.10         highr_0.9              genefilter_1.74.1     
##  [61] desc_1.4.1             caTools_1.18.2         BiocParallel_1.26.2   
##  [64] systemfonts_1.0.4      rlang_1.0.2            pkgconfig_2.0.3       
##  [67] bitops_1.0-7           evaluate_0.15          lattice_0.20-45       
##  [70] htmlwidgets_1.5.4      bit_4.0.4              tidyselect_1.1.2      
##  [73] plyr_1.8.6             magrittr_2.0.2         R6_2.5.1              
##  [76] generics_0.1.2         DelayedArray_0.18.0    DBI_1.1.2             
##  [79] pillar_1.7.0           haven_2.4.3            withr_2.5.0           
##  [82] survival_3.3-1         KEGGREST_1.32.0        RCurl_1.98-1.6        
##  [85] modelr_0.1.8           crayon_1.5.0           KernSmooth_2.23-20    
##  [88] utf8_1.2.2             tzdb_0.2.0             rmarkdown_2.13        
##  [91] locfit_1.5-9.5         grid_4.2.0             readxl_1.3.1          
##  [94] data.table_1.14.2      blob_1.2.2             webshot_0.5.2         
##  [97] reprex_2.0.1           digest_0.6.29          xtable_1.8-4          
## [100] httpuv_1.6.5           munsell_0.5.0          viridisLite_0.4.0     
## [103] bslib_0.3.1

END of report