Mitch Report

date generated: 2022-05-11

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

##                    x
## 5_8S_rRNA -0.2903296
## 7SK       -2.0387409
## A1BG       0.4130886
## A1BG-AS1   1.4168985
## A2M        0.2033726
## A2M-AS1   -0.6904135

Here are some metrics about the input data profile:

Profile metrics

	Profile metrics
num_genesets	2512
num_genes_in_profile	19042
duplicated_genes_present	0
num_profile_genes_in_sets	8746
num_profile_genes_not_in_sets	10296

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used: GMT file of genesets: ReactomePathways.gmt

Gene sets metrics

	Gene sets metrics
num_genesets	2512
num_genesets_excluded	1057
num_genesets_included	1455

Differential pathway expression

Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

set	setSize	pANOVA	s.dist	p.adjustANOVA
Classical antibody-mediated complement activation	53	1.27e-20	-0.7390	1.22e-17
Initial triggering of complement	66	1.89e-20	-0.6590	1.22e-17
Metabolism of RNA	679	2.52e-20	-0.2080	1.22e-17
rRNA processing in the nucleus and cytosol	190	5.35e-19	-0.3740	1.95e-16
Creation of C4 and C2 activators	59	8.70e-19	-0.6660	2.52e-16
Cap-dependent Translation Initiation	118	1.21e-18	-0.4690	2.52e-16
Eukaryotic Translation Initiation	118	1.21e-18	-0.4690	2.52e-16
Regulation of Complement cascade	78	1.86e-18	-0.5740	3.38e-16
Binding and Uptake of Ligands by Scavenger Receptors	82	2.24e-18	-0.5580	3.63e-16
Major pathway of rRNA processing in the nucleolus and cytosol	180	2.66e-18	-0.3770	3.86e-16
Translation	294	3.64e-18	-0.2950	4.81e-16
Formation of a pool of free 40S subunits	100	4.67e-18	-0.5010	5.66e-16
Eukaryotic Translation Elongation	93	6.85e-18	-0.5170	7.67e-16
L13a-mediated translational silencing of Ceruloplasmin expression	110	1.30e-17	-0.4710	1.35e-15
Complement cascade	86	2.52e-17	-0.5280	2.45e-15
Peptide chain elongation	88	3.02e-17	-0.5210	2.72e-15
Metabolism of proteins	1690	3.17e-17	-0.1240	2.72e-15
Infectious disease	772	8.98e-17	-0.1760	7.26e-15
GTP hydrolysis and joining of the 60S ribosomal subunit	111	1.43e-16	-0.4540	1.10e-14
Eukaryotic Translation Termination	92	3.27e-16	-0.4920	2.38e-14
Selenocysteine synthesis	92	3.84e-16	-0.4910	2.62e-14
Regulation of expression of SLITs and ROBOs	163	3.95e-16	-0.3690	2.62e-14
Scavenging of heme from plasma	54	8.85e-16	-0.6320	5.60e-14
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	94	9.29e-16	-0.4790	5.63e-14
Viral mRNA Translation	88	1.80e-15	-0.4900	1.05e-13
SRP-dependent cotranslational protein targeting to membrane	111	8.97e-15	-0.4260	5.02e-13
Selenoamino acid metabolism	115	1.17e-14	-0.4170	6.28e-13
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	114	1.65e-14	-0.4160	8.26e-13
Nonsense-Mediated Decay (NMD)	114	1.65e-14	-0.4160	8.26e-13
Influenza Viral RNA Transcription and Replication	135	2.15e-14	-0.3810	1.04e-12
CD22 mediated BCR regulation	48	2.26e-14	-0.6370	1.06e-12
rRNA processing	214	2.83e-14	-0.3020	1.29e-12
Disease	1456	5.06e-14	-0.1180	2.23e-12
Response of EIF2AK4 (GCN2) to amino acid deficiency	100	5.99e-14	-0.4340	2.56e-12
Regulation of actin dynamics for phagocytic cup formation	109	1.47e-13	-0.4100	6.10e-12
Influenza Infection	154	1.85e-13	-0.3440	7.46e-12
FCGR activation	60	6.05e-13	-0.5370	2.38e-11
Cellular response to starvation	151	6.52e-13	-0.3390	2.50e-11
Role of LAT2/NTAL/LAB on calcium mobilization	57	7.87e-13	-0.5480	2.94e-11
FCGR3A-mediated phagocytosis	107	1.12e-12	-0.3980	3.87e-11
Leishmania phagocytosis	107	1.12e-12	-0.3980	3.87e-11
Parasite infection	107	1.12e-12	-0.3980	3.87e-11
Signaling by ROBO receptors	206	1.28e-12	-0.2870	4.34e-11
Role of phospholipids in phagocytosis	72	6.63e-12	-0.4680	2.19e-10
Fcgamma receptor (FCGR) dependent phagocytosis	133	1.25e-11	-0.3400	4.03e-10
FCERI mediated NF-kB activation	120	4.28e-11	-0.3480	1.35e-09
Metabolism	1834	4.45e-11	-0.0934	1.38e-09
Vesicle-mediated transport	645	1.30e-10	-0.1490	3.94e-09
Cellular responses to stress	663	3.71e-10	-0.1430	1.10e-08
Cellular responses to stimuli	671	7.74e-10	-0.1390	2.25e-08

---

Results (complete table)

Click HERE to show results for all gene sets

Complete results

set	setSize	pANOVA	s.dist	p.adjustANOVA
Classical antibody-mediated complement activation	53	1.27e-20	-7.39e-01	1.22e-17
Initial triggering of complement	66	1.89e-20	-6.59e-01	1.22e-17
Metabolism of RNA	679	2.52e-20	-2.08e-01	1.22e-17
rRNA processing in the nucleus and cytosol	190	5.35e-19	-3.74e-01	1.95e-16
Creation of C4 and C2 activators	59	8.70e-19	-6.66e-01	2.52e-16
Cap-dependent Translation Initiation	118	1.21e-18	-4.69e-01	2.52e-16
Eukaryotic Translation Initiation	118	1.21e-18	-4.69e-01	2.52e-16
Regulation of Complement cascade	78	1.86e-18	-5.74e-01	3.38e-16
Binding and Uptake of Ligands by Scavenger Receptors	82	2.24e-18	-5.58e-01	3.63e-16
Major pathway of rRNA processing in the nucleolus and cytosol	180	2.66e-18	-3.77e-01	3.86e-16
Translation	294	3.64e-18	-2.95e-01	4.81e-16
Formation of a pool of free 40S subunits	100	4.67e-18	-5.01e-01	5.66e-16
Eukaryotic Translation Elongation	93	6.85e-18	-5.17e-01	7.67e-16
L13a-mediated translational silencing of Ceruloplasmin expression	110	1.30e-17	-4.71e-01	1.35e-15
Complement cascade	86	2.52e-17	-5.28e-01	2.45e-15
Peptide chain elongation	88	3.02e-17	-5.21e-01	2.72e-15
Metabolism of proteins	1690	3.17e-17	-1.24e-01	2.72e-15
Infectious disease	772	8.98e-17	-1.76e-01	7.26e-15
GTP hydrolysis and joining of the 60S ribosomal subunit	111	1.43e-16	-4.54e-01	1.10e-14
Eukaryotic Translation Termination	92	3.27e-16	-4.92e-01	2.38e-14
Selenocysteine synthesis	92	3.84e-16	-4.91e-01	2.62e-14
Regulation of expression of SLITs and ROBOs	163	3.95e-16	-3.69e-01	2.62e-14
Scavenging of heme from plasma	54	8.85e-16	-6.32e-01	5.60e-14
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	94	9.29e-16	-4.79e-01	5.63e-14
Viral mRNA Translation	88	1.80e-15	-4.90e-01	1.05e-13
SRP-dependent cotranslational protein targeting to membrane	111	8.97e-15	-4.26e-01	5.02e-13
Selenoamino acid metabolism	115	1.17e-14	-4.17e-01	6.28e-13
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	114	1.65e-14	-4.16e-01	8.26e-13
Nonsense-Mediated Decay (NMD)	114	1.65e-14	-4.16e-01	8.26e-13
Influenza Viral RNA Transcription and Replication	135	2.15e-14	-3.81e-01	1.04e-12
CD22 mediated BCR regulation	48	2.26e-14	-6.37e-01	1.06e-12
rRNA processing	214	2.83e-14	-3.02e-01	1.29e-12
Disease	1456	5.06e-14	-1.18e-01	2.23e-12
Response of EIF2AK4 (GCN2) to amino acid deficiency	100	5.99e-14	-4.34e-01	2.56e-12
Regulation of actin dynamics for phagocytic cup formation	109	1.47e-13	-4.10e-01	6.10e-12
Influenza Infection	154	1.85e-13	-3.44e-01	7.46e-12
FCGR activation	60	6.05e-13	-5.37e-01	2.38e-11
Cellular response to starvation	151	6.52e-13	-3.39e-01	2.50e-11
Role of LAT2/NTAL/LAB on calcium mobilization	57	7.87e-13	-5.48e-01	2.94e-11
FCGR3A-mediated phagocytosis	107	1.12e-12	-3.98e-01	3.87e-11
Leishmania phagocytosis	107	1.12e-12	-3.98e-01	3.87e-11
Parasite infection	107	1.12e-12	-3.98e-01	3.87e-11
Signaling by ROBO receptors	206	1.28e-12	-2.87e-01	4.34e-11
Role of phospholipids in phagocytosis	72	6.63e-12	-4.68e-01	2.19e-10
Fcgamma receptor (FCGR) dependent phagocytosis	133	1.25e-11	-3.40e-01	4.03e-10
FCERI mediated NF-kB activation	120	4.28e-11	-3.48e-01	1.35e-09
Metabolism	1834	4.45e-11	-9.34e-02	1.38e-09
Vesicle-mediated transport	645	1.30e-10	-1.49e-01	3.94e-09
Cellular responses to stress	663	3.71e-10	-1.43e-01	1.10e-08
Cellular responses to stimuli	671	7.74e-10	-1.39e-01	2.25e-08
Metabolism of amino acids and derivatives	332	1.07e-09	-1.95e-01	3.07e-08
FCERI mediated Ca+2 mobilization	72	3.97e-09	-4.01e-01	1.11e-07
FCGR3A-mediated IL10 synthesis	84	4.98e-09	-3.69e-01	1.37e-07
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S	59	6.73e-09	-4.36e-01	1.81e-07
Translation initiation complex formation	58	1.42e-08	-4.30e-01	3.76e-07
FCERI mediated MAPK activation	73	1.96e-08	-3.80e-01	5.10e-07
Formation of the ternary complex, and subsequently, the 43S complex	51	2.02e-08	-4.54e-01	5.13e-07
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	72	2.04e-08	-3.82e-01	5.13e-07
Diseases of metabolism	207	6.05e-08	-2.19e-01	1.48e-06
Ribosomal scanning and start codon recognition	58	6.12e-08	-4.11e-01	1.48e-06
Post-translational protein modification	1228	1.22e-07	-9.01e-02	2.91e-06
Signaling by the B Cell Receptor (BCR)	150	2.16e-07	-2.45e-01	5.07e-06
Axon guidance	488	5.84e-07	-1.32e-01	1.35e-05
Elastic fibre formation	37	1.45e-06	-4.58e-01	3.31e-05
Fc epsilon receptor (FCERI) signaling	173	1.77e-06	-2.11e-01	3.97e-05
Asparagine N-linked glycosylation	271	2.06e-06	-1.68e-01	4.54e-05
mRNA Splicing - Major Pathway	179	2.55e-06	-2.04e-01	5.54e-05
Leishmania infection	236	2.83e-06	-1.77e-01	6.05e-05
Diseases of glycosylation	127	3.28e-06	-2.39e-01	6.91e-05
Post-translational protein phosphorylation	78	3.45e-06	-3.04e-01	7.17e-05
Processing of Capped Intron-Containing Pre-mRNA	238	3.61e-06	-1.74e-01	7.39e-05
mRNA Splicing	187	4.38e-06	-1.95e-01	8.84e-05
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)	88	4.82e-06	-2.82e-01	9.60e-05
XBP1(S) activates chaperone genes	48	6.02e-06	-3.78e-01	1.18e-04
Nervous system development	510	6.54e-06	-1.17e-01	1.27e-04
Metabolism of carbohydrates	261	9.16e-06	-1.60e-01	1.75e-04
HIV Infection	225	1.06e-05	-1.71e-01	2.00e-04
Cell surface interactions at the vascular wall	157	1.17e-05	-2.03e-01	2.19e-04
IRE1alpha activates chaperones	50	1.19e-05	-3.58e-01	2.20e-04
Glycosaminoglycan metabolism	107	1.93e-05	-2.39e-01	3.51e-04
Chemokine receptors bind chemokines	41	3.71e-05	3.72e-01	6.66e-04
Hedgehog ‘on’ state	82	3.89e-05	-2.63e-01	6.80e-04
Pausing and recovery of Tat-mediated HIV elongation	30	3.92e-05	-4.34e-01	6.80e-04
Tat-mediated HIV elongation arrest and recovery	30	3.92e-05	-4.34e-01	6.80e-04
Anti-inflammatory response favouring Leishmania parasite infection	155	4.11e-05	-1.91e-01	6.96e-04
Leishmania parasite growth and survival	155	4.11e-05	-1.91e-01	6.96e-04
Diseases associated with glycosaminoglycan metabolism	36	4.76e-05	-3.92e-01	7.97e-04
Cellular response to chemical stress	151	5.12e-05	-1.91e-01	8.47e-04
Innate Immune System	955	6.58e-05	-7.65e-02	1.07e-03
Extracellular matrix organization	256	6.64e-05	-1.45e-01	1.07e-03
Signaling by Hedgehog	129	6.73e-05	-2.03e-01	1.08e-03
Heparan sulfate/heparin (HS-GAG) metabolism	45	8.26e-05	-3.39e-01	1.31e-03
COPI-mediated anterograde transport	80	9.28e-05	-2.53e-01	1.45e-03
PCP/CE pathway	88	9.94e-05	-2.40e-01	1.54e-03
HIV elongation arrest and recovery	32	1.46e-04	-3.88e-01	2.21e-03
Pausing and recovery of HIV elongation	32	1.46e-04	-3.88e-01	2.21e-03
Degradation of DVL	54	1.52e-04	-2.98e-01	2.28e-03
Cardiac conduction	101	1.72e-04	2.16e-01	2.55e-03
Scavenging by Class A Receptors	17	1.78e-04	-5.25e-01	2.61e-03
GPCR ligand binding	250	1.79e-04	1.38e-01	2.61e-03
UCH proteinases	86	2.08e-04	-2.31e-01	2.97e-03
Hedgehog ‘off’ state	95	2.08e-04	-2.20e-01	2.97e-03
Chondroitin sulfate/dermatan sulfate metabolism	46	2.13e-04	-3.16e-01	3.01e-03
ROS sensing by NFE2L2	55	2.16e-04	-2.88e-01	3.02e-03
Vpu mediated degradation of CD4	50	2.31e-04	-3.01e-01	3.20e-03
Nucleotide Excision Repair	110	2.47e-04	-2.02e-01	3.39e-03
AUF1 (hnRNP D0) binds and destabilizes mRNA	53	2.58e-04	-2.90e-01	3.51e-03
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis	53	2.91e-04	-2.88e-01	3.89e-03
SCF-beta-TrCP mediated degradation of Emi1	53	2.91e-04	-2.88e-01	3.89e-03
Regulation of RUNX3 expression and activity	55	3.24e-04	-2.80e-01	4.27e-03
Abortive elongation of HIV-1 transcript in the absence of Tat	23	3.26e-04	-4.33e-01	4.27e-03
Peptide ligand-binding receptors	102	3.36e-04	2.06e-01	4.33e-03
Hh mutants are degraded by ERAD	53	3.36e-04	-2.85e-01	4.33e-03
Class A/1 (Rhodopsin-like receptors)	180	3.47e-04	1.55e-01	4.43e-03
Membrane Trafficking	566	3.71e-04	-8.77e-02	4.68e-03
Molecules associated with elastic fibres	28	3.73e-04	-3.89e-01	4.68e-03
Defective CFTR causes cystic fibrosis	59	3.83e-04	-2.67e-01	4.77e-03
Host Interactions of HIV factors	128	3.99e-04	-1.81e-01	4.92e-03
Hh mutants abrogate ligand secretion	55	4.47e-04	-2.74e-01	5.47e-03
rRNA modification in the nucleus and cytosol	59	4.66e-04	-2.63e-01	5.65e-03
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A	50	4.80e-04	-2.85e-01	5.68e-03
p53-Independent DNA Damage Response	50	4.80e-04	-2.85e-01	5.68e-03
p53-Independent G1/S DNA damage checkpoint	50	4.80e-04	-2.85e-01	5.68e-03
GLI3 is processed to GLI3R by the proteasome	57	4.87e-04	-2.67e-01	5.71e-03
Degradation of GLI2 by the proteasome	57	4.92e-04	-2.67e-01	5.72e-03
mRNA Splicing - Minor Pathway	52	5.05e-04	-2.79e-01	5.83e-03
Unfolded Protein Response (UPR)	90	5.89e-04	-2.10e-01	6.74e-03
Interleukin-10 signaling	38	6.18e-04	3.21e-01	7.00e-03
Degradation of AXIN	53	6.24e-04	-2.72e-01	7.00e-03
Negative regulation of NOTCH4 signaling	54	6.26e-04	-2.69e-01	7.00e-03
Ubiquitin-dependent degradation of Cyclin D	50	6.43e-04	-2.79e-01	7.14e-03
NGF-stimulated transcription	35	6.74e-04	3.32e-01	7.43e-03
Regulation of HMOX1 expression and activity	63	7.20e-04	-2.46e-01	7.87e-03
Degradation of GLI1 by the proteasome	57	7.43e-04	-2.58e-01	8.06e-03
Formation of HIV-1 elongation complex containing HIV-1 Tat	42	7.77e-04	-3.00e-01	8.25e-03
HIV Transcription Elongation	42	7.77e-04	-3.00e-01	8.25e-03
Tat-mediated elongation of the HIV-1 transcript	42	7.77e-04	-3.00e-01	8.25e-03
Olfactory Signaling Pathway	14	7.97e-04	5.18e-01	8.41e-03
HS-GAG degradation	20	8.49e-04	-4.31e-01	8.88e-03
Transport to the Golgi and subsequent modification	157	8.71e-04	-1.54e-01	9.06e-03
Muscle contraction	163	9.05e-04	1.51e-01	9.33e-03
Regulation of activated PAK-2p34 by proteasome mediated degradation	48	9.20e-04	-2.76e-01	9.42e-03
Vif-mediated degradation of APOBEC3G	52	9.26e-04	-2.66e-01	9.42e-03
G alpha (q) signalling events	145	9.53e-04	1.59e-01	9.63e-03
Autodegradation of the E3 ubiquitin ligase COP1	49	9.64e-04	-2.73e-01	9.67e-03
Regulation of Apoptosis	51	1.01e-03	-2.66e-01	1.00e-02
ER to Golgi Anterograde Transport	131	1.03e-03	-1.66e-01	1.02e-02
Autophagy	129	1.09e-03	-1.67e-01	1.08e-02
NIK–>noncanonical NF-kB signaling	57	1.29e-03	-2.47e-01	1.25e-02
Autodegradation of Cdh1 by Cdh1:APC/C	63	1.30e-03	-2.34e-01	1.25e-02
Developmental Biology	785	1.30e-03	-6.77e-02	1.25e-02
Signaling by NOTCH4	81	1.38e-03	-2.06e-01	1.32e-02
Late Phase of HIV Life Cycle	133	1.42e-03	-1.60e-01	1.35e-02
Protein localization	159	1.45e-03	-1.46e-01	1.37e-02
Phase 0 - rapid depolarisation	28	1.45e-03	3.48e-01	1.37e-02
Cytoprotection by HMOX1	119	1.49e-03	-1.69e-01	1.39e-02
Defective B3GAT3 causes JDSSDHD	17	1.56e-03	-4.43e-01	1.45e-02
DNA Damage Recognition in GG-NER	38	1.63e-03	-2.95e-01	1.50e-02
Defective B3GALT6 causes EDSP2 and SEMDJL1	17	1.70e-03	-4.40e-01	1.55e-02
Formation of HIV elongation complex in the absence of HIV Tat	44	1.76e-03	-2.73e-01	1.60e-02
Stabilization of p53	54	1.83e-03	-2.45e-01	1.65e-02
The role of GTSE1 in G2/M progression after G2 checkpoint	58	1.84e-03	-2.36e-01	1.65e-02
Dectin-1 mediated noncanonical NF-kB signaling	59	2.05e-03	-2.32e-01	1.83e-02
CS/DS degradation	12	2.07e-03	-5.14e-01	1.83e-02
Defective B4GALT7 causes EDS, progeroid type	17	2.23e-03	-4.28e-01	1.95e-02
Synthesis of substrates in N-glycan biosythesis	57	2.23e-03	-2.34e-01	1.95e-02
APC/C:Cdc20 mediated degradation of Securin	65	2.32e-03	-2.19e-01	2.02e-02
Hedgehog ligand biogenesis	60	2.34e-03	-2.27e-01	2.03e-02
ABC transporter disorders	73	2.38e-03	-2.06e-01	2.05e-02
Formation of the Early Elongation Complex	33	2.45e-03	-3.05e-01	2.08e-02
Formation of the HIV-1 Early Elongation Complex	33	2.45e-03	-3.05e-01	2.08e-02
Ca2+ pathway	56	2.51e-03	2.34e-01	2.12e-02
Macroautophagy	114	2.54e-03	-1.64e-01	2.14e-02
Regulation of mRNA stability by proteins that bind AU-rich elements	87	2.65e-03	-1.86e-01	2.21e-02
Cross-presentation of soluble exogenous antigens (endosomes)	47	2.90e-03	-2.51e-01	2.41e-02
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins	71	2.97e-03	-2.04e-01	2.45e-02
A tetrasaccharide linker sequence is required for GAG synthesis	23	3.07e-03	-3.57e-01	2.53e-02
Orc1 removal from chromatin	67	3.13e-03	-2.09e-01	2.56e-02
Signaling by GPCR	456	3.32e-03	8.04e-02	2.70e-02
Regulation of APC/C activators between G1/S and early anaphase	76	3.48e-03	-1.94e-01	2.81e-02
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	21	3.50e-03	-3.68e-01	2.81e-02
Cellular response to hypoxia	71	3.78e-03	-1.99e-01	3.02e-02
Transcription-Coupled Nucleotide Excision Repair (TC-NER)	78	3.97e-03	-1.89e-01	3.16e-02
Degradation of beta-catenin by the destruction complex	83	4.10e-03	-1.82e-01	3.24e-02
SCF(Skp2)-mediated degradation of p27/p21	59	4.16e-03	-2.16e-01	3.27e-02
HIV Life Cycle	146	4.37e-03	-1.37e-01	3.42e-02
Formation of RNA Pol II elongation complex	57	4.48e-03	-2.18e-01	3.47e-02
RNA Polymerase II Transcription Elongation	57	4.48e-03	-2.18e-01	3.47e-02
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint	68	4.59e-03	-1.99e-01	3.51e-02
Cdc20:Phospho-APC/C mediated degradation of Cyclin A	68	4.59e-03	-1.99e-01	3.51e-02
Mitochondrial translation elongation	90	4.81e-03	-1.72e-01	3.67e-02
Global Genome Nucleotide Excision Repair (GG-NER)	84	4.84e-03	-1.78e-01	3.67e-02
Asymmetric localization of PCP proteins	62	4.88e-03	-2.07e-01	3.68e-02
APC/C:Cdc20 mediated degradation of mitotic proteins	70	5.03e-03	-1.94e-01	3.77e-02
DNA Repair	283	5.08e-03	-9.69e-02	3.79e-02
Transcriptional Regulation by MECP2	52	5.35e-03	2.23e-01	3.97e-02
Platelet homeostasis	73	5.42e-03	1.88e-01	4.01e-02
Diseases of carbohydrate metabolism	30	5.58e-03	-2.92e-01	4.08e-02
Assembly of active LPL and LIPC lipase complexes	13	5.58e-03	-4.44e-01	4.08e-02
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	14	5.65e-03	-4.27e-01	4.11e-02
Disorders of transmembrane transporters	150	6.05e-03	-1.30e-01	4.38e-02
Cytosolic iron-sulfur cluster assembly	13	6.21e-03	-4.38e-01	4.46e-02
MECP2 regulates neuronal receptors and channels	17	6.25e-03	3.83e-01	4.46e-02
Mitochondrial translation initiation	90	6.26e-03	-1.67e-01	4.46e-02
Regulation of PTEN stability and activity	67	6.31e-03	-1.93e-01	4.46e-02
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha	64	6.32e-03	-1.97e-01	4.46e-02
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	71	6.41e-03	-1.87e-01	4.51e-02
Intra-Golgi and retrograde Golgi-to-ER traffic	173	6.51e-03	-1.20e-01	4.55e-02
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling	25	6.76e-03	3.13e-01	4.71e-02
GPCR downstream signalling	408	6.85e-03	7.81e-02	4.75e-02
G2/M Transition	177	7.07e-03	-1.17e-01	4.88e-02
Gap-filling DNA repair synthesis and ligation in TC-NER	64	7.35e-03	-1.94e-01	5.04e-02
Transcriptional regulation of granulopoiesis	40	7.38e-03	2.45e-01	5.04e-02
Transmission across Chemical Synapses	185	7.48e-03	1.14e-01	5.08e-02
CDT1 association with the CDC6:ORC:origin complex	56	7.56e-03	-2.06e-01	5.08e-02
Hyaluronan uptake and degradation	11	7.58e-03	-4.65e-01	5.08e-02
Plasma lipoprotein assembly, remodeling, and clearance	55	7.60e-03	-2.08e-01	5.08e-02
G alpha (i) signalling events	200	7.62e-03	1.10e-01	5.08e-02
CDK-mediated phosphorylation and removal of Cdc6	69	7.69e-03	-1.86e-01	5.11e-02
Regulation of ornithine decarboxylase (ODC)	49	7.81e-03	-2.20e-01	5.17e-02
Retrograde neurotrophin signalling	13	8.11e-03	-4.24e-01	5.34e-02
Nuclear Events (kinase and transcription factor activation)	57	8.19e-03	2.03e-01	5.36e-02
TNFR2 non-canonical NF-kB pathway	92	8.22e-03	-1.59e-01	5.36e-02
TBC/RABGAPs	44	8.29e-03	-2.30e-01	5.39e-02
Switching of origins to a post-replicative state	86	8.49e-03	-1.64e-01	5.49e-02
Synthesis, secretion, and deacylation of Ghrelin	14	8.66e-03	4.05e-01	5.58e-02
Mitotic G2-G2/M phases	179	8.72e-03	-1.14e-01	5.58e-02
COPI-dependent Golgi-to-ER retrograde traffic	73	8.74e-03	-1.78e-01	5.58e-02
Phase I - Functionalization of compounds	72	8.87e-03	-1.78e-01	5.63e-02
Neuronal System	278	8.91e-03	9.12e-02	5.64e-02
Interferon Signaling	179	9.41e-03	1.13e-01	5.92e-02
Cyclin A:Cdk2-associated events at S phase entry	84	9.44e-03	-1.64e-01	5.92e-02
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	72	9.49e-03	-1.77e-01	5.93e-02
Chromatin modifying enzymes	210	9.72e-03	-1.04e-01	6.02e-02
Chromatin organization	210	9.72e-03	-1.04e-01	6.02e-02
Biological oxidations	147	9.86e-03	-1.23e-01	6.08e-02
Sensory processing of sound by outer hair cells of the cochlea	38	9.91e-03	-2.42e-01	6.09e-02
MHC class II antigen presentation	95	1.01e-02	-1.53e-01	6.17e-02
Mitochondrial translation	96	1.03e-02	-1.52e-01	6.25e-02
Assembly of the ORC complex at the origin of replication	18	1.03e-02	3.49e-01	6.25e-02
Dual incision in TC-NER	65	1.04e-02	-1.84e-01	6.26e-02
Mucopolysaccharidoses	11	1.04e-02	-4.46e-01	6.28e-02
Regulation of TP53 Activity through Acetylation	29	1.07e-02	-2.74e-01	6.43e-02
Synthesis of DNA	114	1.09e-02	-1.38e-01	6.52e-02
Metabolism of porphyrins	21	1.11e-02	-3.20e-01	6.60e-02
Interleukin-6 signaling	11	1.12e-02	4.42e-01	6.62e-02
p75 NTR receptor-mediated signalling	91	1.13e-02	-1.54e-01	6.68e-02
Mitochondrial translation termination	90	1.16e-02	-1.54e-01	6.83e-02
Late endosomal microautophagy	32	1.18e-02	-2.57e-01	6.88e-02
Activation of NF-kappaB in B cells	65	1.25e-02	-1.79e-01	7.26e-02
Sema3A PAK dependent Axon repulsion	16	1.32e-02	-3.58e-01	7.67e-02
Ras activation upon Ca2+ influx through NMDA receptor	17	1.35e-02	3.46e-01	7.81e-02
trans-Golgi Network Vesicle Budding	69	1.36e-02	-1.72e-01	7.85e-02
Metabolism of polyamines	57	1.38e-02	-1.89e-01	7.88e-02
Transcriptional regulation by RUNX2	115	1.40e-02	-1.33e-01	7.99e-02
Defective HDR through Homologous Recombination (HRR) due to BRCA1 loss-of-function	23	1.44e-02	2.95e-01	8.04e-02
Defective HDR through Homologous Recombination (HRR) due to PALB2 loss of function	23	1.44e-02	2.95e-01	8.04e-02
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function	23	1.44e-02	2.95e-01	8.04e-02
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function	23	1.44e-02	2.95e-01	8.04e-02
Diseases of DNA Double-Strand Break Repair	23	1.44e-02	2.95e-01	8.04e-02
Formation of TC-NER Pre-Incision Complex	53	1.45e-02	-1.94e-01	8.09e-02
WNT5A-dependent internalization of FZD2, FZD5 and ROR2	13	1.47e-02	-3.91e-01	8.13e-02
Post NMDA receptor activation events	56	1.47e-02	1.89e-01	8.13e-02
Sensory processing of sound by inner hair cells of the cochlea	49	1.50e-02	-2.01e-01	8.26e-02
Neurotransmitter receptors and postsynaptic signal transmission	137	1.55e-02	1.20e-01	8.47e-02
Golgi-to-ER retrograde transport	106	1.55e-02	-1.36e-01	8.47e-02
Lysosome Vesicle Biogenesis	32	1.56e-02	-2.47e-01	8.49e-02
Defective EXT1 causes exostoses 1, TRPS2 and CHDS	13	1.57e-02	-3.87e-01	8.51e-02
Defective EXT2 causes exostoses 2	13	1.57e-02	-3.87e-01	8.51e-02
Unblocking of NMDA receptors, glutamate binding and activation	18	1.63e-02	3.27e-01	8.77e-02
PTEN Regulation	139	1.67e-02	-1.18e-01	8.95e-02
RNA Polymerase III Transcription Initiation	36	1.68e-02	-2.30e-01	8.99e-02
Detoxification of Reactive Oxygen Species	33	1.70e-02	-2.40e-01	9.07e-02
Resolution of Abasic Sites (AP sites)	38	1.72e-02	-2.23e-01	9.15e-02
Cytosolic sensors of pathogen-associated DNA	63	1.80e-02	-1.72e-01	9.49e-02
ECM proteoglycans	46	1.80e-02	-2.02e-01	9.49e-02
RNA Polymerase III Chain Elongation	18	1.84e-02	-3.21e-01	9.65e-02
Endosomal Sorting Complex Required For Transport (ESCRT)	31	1.86e-02	-2.44e-01	9.73e-02
rRNA processing in the mitochondrion	24	1.93e-02	2.76e-01	1.01e-01
Cyclin E associated events during G1/S transition	82	2.11e-02	-1.47e-01	1.10e-01
Inositol phosphate metabolism	43	2.13e-02	2.03e-01	1.10e-01
Platelet degranulation	113	2.14e-02	-1.25e-01	1.10e-01
Transcriptional regulation of pluripotent stem cells	20	2.15e-02	2.97e-01	1.11e-01
CRMPs in Sema3A signaling	15	2.18e-02	-3.42e-01	1.11e-01
Sensory processing of sound	54	2.18e-02	-1.80e-01	1.11e-01
RNA Polymerase III Transcription Initiation From Type 3 Promoter	28	2.21e-02	-2.50e-01	1.13e-01
Nitric oxide stimulates guanylate cyclase	19	2.25e-02	3.02e-01	1.14e-01
Interferon gamma signaling	85	2.34e-02	1.42e-01	1.18e-01
RNA Polymerase III Abortive And Retractive Initiation	41	2.41e-02	-2.04e-01	1.20e-01
RNA Polymerase III Transcription	41	2.41e-02	-2.04e-01	1.20e-01
Signaling by ERBB2 in Cancer	24	2.41e-02	2.66e-01	1.20e-01
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	35	2.43e-02	-2.20e-01	1.21e-01
Long-term potentiation	20	2.46e-02	2.90e-01	1.22e-01
Transcription of the HIV genome	67	2.49e-02	-1.59e-01	1.23e-01
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding	28	2.52e-02	-2.44e-01	1.24e-01
Signaling by FGFR2 IIIa TM	19	2.59e-02	-2.95e-01	1.27e-01
Diseases associated with glycosylation precursor biosynthesis	18	2.65e-02	-3.02e-01	1.30e-01
Activation of NMDA receptors and postsynaptic events	68	2.75e-02	1.55e-01	1.34e-01
Assembly of the pre-replicative complex	78	2.79e-02	-1.44e-01	1.36e-01
Plasma lipoprotein remodeling	21	2.84e-02	-2.76e-01	1.38e-01
SHC1 events in ERBB4 signaling	12	2.87e-02	3.65e-01	1.38e-01
Mitochondrial protein import	64	2.88e-02	-1.58e-01	1.38e-01
G1/S DNA Damage Checkpoints	64	2.88e-02	-1.58e-01	1.38e-01
APC/C-mediated degradation of cell cycle proteins	82	2.89e-02	-1.40e-01	1.38e-01
Regulation of mitotic cell cycle	82	2.89e-02	-1.40e-01	1.38e-01
p53-Dependent G1 DNA Damage Response	62	2.97e-02	-1.60e-01	1.41e-01
p53-Dependent G1/S DNA damage checkpoint	62	2.97e-02	-1.60e-01	1.41e-01
Ion homeostasis	47	2.99e-02	1.83e-01	1.41e-01
Signaling by ERBB2 KD Mutants	23	3.00e-02	2.61e-01	1.41e-01
Glycosphingolipid metabolism	37	3.04e-02	-2.06e-01	1.43e-01
RNA Polymerase II Pre-transcription Events	78	3.12e-02	-1.41e-01	1.46e-01
Chaperonin-mediated protein folding	79	3.13e-02	-1.40e-01	1.46e-01
Regulation of RUNX2 expression and activity	71	3.15e-02	-1.48e-01	1.46e-01
Interferon alpha/beta signaling	56	3.15e-02	1.66e-01	1.46e-01
Cell-extracellular matrix interactions	16	3.21e-02	-3.10e-01	1.48e-01
Establishment of Sister Chromatid Cohesion	10	3.24e-02	3.91e-01	1.49e-01
Metabolism of vitamins and cofactors	165	3.25e-02	-9.65e-02	1.49e-01
ABC-family proteins mediated transport	97	3.25e-02	-1.26e-01	1.49e-01
Hyaluronan metabolism	16	3.30e-02	-3.08e-01	1.50e-01
RNA Pol II CTD phosphorylation and interaction with CE	27	3.30e-02	-2.37e-01	1.50e-01
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection	27	3.30e-02	-2.37e-01	1.50e-01
Phase 2 - plateau phase	12	3.40e-02	3.53e-01	1.53e-01
SHC1 events in ERBB2 signaling	20	3.40e-02	2.74e-01	1.53e-01
Protein folding	85	3.41e-02	-1.33e-01	1.53e-01
Activation of Matrix Metalloproteinases	24	3.43e-02	-2.50e-01	1.53e-01
PI3K events in ERBB2 signaling	14	3.48e-02	3.26e-01	1.55e-01
RNA Polymerase III Transcription Termination	23	3.52e-02	-2.54e-01	1.56e-01
RNA Polymerase III Transcription Initiation From Type 1 Promoter	28	3.54e-02	-2.30e-01	1.57e-01
CDC6 association with the ORC:origin complex	10	3.64e-02	3.82e-01	1.61e-01
P2Y receptors	11	3.65e-02	3.64e-01	1.61e-01
HS-GAG biosynthesis	24	3.77e-02	-2.45e-01	1.65e-01
Response to elevated platelet cytosolic Ca2+	117	3.77e-02	-1.11e-01	1.65e-01
Association of TriC/CCT with target proteins during biosynthesis	37	3.77e-02	-1.97e-01	1.65e-01
ER-Phagosome pathway	85	3.81e-02	-1.30e-01	1.66e-01
Regulation of RAS by GAPs	64	3.81e-02	-1.50e-01	1.66e-01
Interleukin-4 and Interleukin-13 signaling	95	3.90e-02	1.23e-01	1.69e-01
RMTs methylate histone arginines	35	3.94e-02	-2.01e-01	1.70e-01
Regulation of innate immune responses to cytosolic DNA	14	4.01e-02	-3.17e-01	1.72e-01
Sealing of the nuclear envelope (NE) by ESCRT-III	25	4.05e-02	-2.37e-01	1.74e-01
Budding and maturation of HIV virion	28	4.14e-02	-2.23e-01	1.77e-01
Sulfur amino acid metabolism	26	4.23e-02	-2.30e-01	1.80e-01
tRNA Aminoacylation	42	4.30e-02	-1.81e-01	1.83e-01
Reduction of cytosolic Ca++ levels	10	4.35e-02	3.69e-01	1.84e-01
RNA Polymerase III Transcription Initiation From Type 2 Promoter	27	4.43e-02	-2.24e-01	1.87e-01
Gamma carboxylation, hypusine formation and arylsulfatase activation	34	4.52e-02	-1.98e-01	1.91e-01
Synthesis of PIPs at the late endosome membrane	11	4.55e-02	3.48e-01	1.91e-01
Synthesis of PIPs at the early endosome membrane	16	4.58e-02	2.88e-01	1.92e-01
DNA Damage/Telomere Stress Induced Senescence	37	4.59e-02	1.90e-01	1.92e-01
Signaling by FGFR1 in disease	34	4.63e-02	1.97e-01	1.93e-01
Striated Muscle Contraction	34	4.70e-02	1.97e-01	1.94e-01
Platelet calcium homeostasis	23	4.70e-02	2.39e-01	1.94e-01
Rab regulation of trafficking	119	4.70e-02	-1.05e-01	1.94e-01
Cell death signalling via NRAGE, NRIF and NADE	73	4.73e-02	-1.34e-01	1.95e-01
Degradation of cysteine and homocysteine	13	4.76e-02	-3.17e-01	1.95e-01
Plasma lipoprotein clearance	30	4.80e-02	-2.09e-01	1.97e-01
Activation of SMO	16	4.81e-02	-2.85e-01	1.97e-01
Prefoldin mediated transfer of substrate to CCT/TriC	26	4.85e-02	-2.24e-01	1.97e-01
RAF-independent MAPK1/3 activation	22	4.86e-02	2.43e-01	1.97e-01
VLDLR internalisation and degradation	11	4.88e-02	-3.43e-01	1.97e-01
Collagen formation	82	4.88e-02	-1.26e-01	1.97e-01
LDL clearance	18	4.90e-02	-2.68e-01	1.97e-01
Insulin processing	22	4.91e-02	2.42e-01	1.97e-01
Metabolism of fat-soluble vitamins	35	5.07e-02	-1.91e-01	2.03e-01
Antigen processing-Cross presentation	100	5.10e-02	-1.13e-01	2.04e-01
Cytokine Signaling in Immune system	610	5.11e-02	4.64e-02	2.04e-01
Formation of tubulin folding intermediates by CCT/TriC	21	5.14e-02	-2.46e-01	2.04e-01
Rap1 signalling	15	5.16e-02	2.90e-01	2.05e-01
tRNA processing in the nucleus	59	5.18e-02	-1.46e-01	2.05e-01
Downstream TCR signaling	94	5.36e-02	-1.15e-01	2.11e-01
O-linked glycosylation	90	5.41e-02	-1.17e-01	2.13e-01
Crosslinking of collagen fibrils	10	5.42e-02	-3.52e-01	2.13e-01
FGFR2 alternative splicing	25	5.45e-02	-2.22e-01	2.13e-01
Diseases associated with O-glycosylation of proteins	57	5.54e-02	-1.47e-01	2.16e-01
Presynaptic phase of homologous DNA pairing and strand exchange	38	5.56e-02	1.79e-01	2.16e-01
WNT5A-dependent internalization of FZD4	14	5.59e-02	-2.95e-01	2.17e-01
MicroRNA (miRNA) biogenesis	25	5.61e-02	-2.21e-01	2.17e-01
ESR-mediated signaling	158	5.66e-02	8.79e-02	2.18e-01
Aspartate and asparagine metabolism	11	5.68e-02	3.32e-01	2.18e-01
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	11	5.79e-02	3.30e-01	2.22e-01
mRNA decay by 3’ to 5’ exoribonuclease	16	5.81e-02	-2.74e-01	2.22e-01
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	147	5.84e-02	-9.05e-02	2.23e-01
mRNA Capping	29	5.90e-02	-2.03e-01	2.25e-01
GRB2 events in EGFR signaling	11	5.99e-02	3.28e-01	2.27e-01
EPH-Ephrin signaling	86	6.02e-02	-1.17e-01	2.28e-01
Mitophagy	28	6.04e-02	-2.05e-01	2.28e-01
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	10	6.07e-02	-3.43e-01	2.28e-01
Gap-filling DNA repair synthesis and ligation in GG-NER	25	6.08e-02	-2.17e-01	2.28e-01
Iron uptake and transport	56	6.09e-02	-1.45e-01	2.28e-01
Signaling by ERBB2 TMD/JMD mutants	20	6.24e-02	2.41e-01	2.33e-01
RNA Polymerase II Transcription Termination	65	6.30e-02	-1.33e-01	2.35e-01
Transport of Mature Transcript to Cytoplasm	81	6.32e-02	-1.19e-01	2.35e-01
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	15	6.33e-02	-2.77e-01	2.35e-01
RND2 GTPase cycle	37	6.39e-02	-1.76e-01	2.36e-01
Centrosome maturation	80	6.46e-02	-1.20e-01	2.38e-01
Recruitment of mitotic centrosome proteins and complexes	80	6.46e-02	-1.20e-01	2.38e-01
FOXO-mediated transcription of cell cycle genes	16	6.47e-02	2.67e-01	2.38e-01
RUNX1 regulates transcription of genes involved in differentiation of HSCs	77	6.48e-02	-1.22e-01	2.38e-01
Regulation of insulin secretion	62	6.53e-02	1.35e-01	2.39e-01
HCMV Infection	91	6.59e-02	-1.12e-01	2.40e-01
Resolution of Sister Chromatid Cohesion	97	6.62e-02	1.08e-01	2.40e-01
Viral Messenger RNA Synthesis	44	6.62e-02	-1.60e-01	2.40e-01
Amino acids regulate mTORC1	51	6.62e-02	-1.49e-01	2.40e-01
Interleukin receptor SHC signaling	22	6.68e-02	2.26e-01	2.41e-01
Assembly Of The HIV Virion	16	6.71e-02	-2.64e-01	2.42e-01
Death Receptor Signalling	135	6.77e-02	-9.11e-02	2.43e-01
SARS-CoV Infections	152	6.84e-02	-8.57e-02	2.45e-01
SHC1 events in EGFR signaling	12	6.93e-02	3.03e-01	2.46e-01
Termination of O-glycan biosynthesis	14	6.94e-02	-2.80e-01	2.46e-01
GRB2 events in ERBB2 signaling	14	6.94e-02	2.80e-01	2.46e-01
Folding of actin by CCT/TriC	10	6.95e-02	-3.32e-01	2.46e-01
Keratan sulfate degradation	11	6.96e-02	-3.16e-01	2.46e-01
Regulation of PTEN mRNA translation	12	6.98e-02	3.02e-01	2.46e-01
Inwardly rectifying K+ channels	24	6.99e-02	2.14e-01	2.46e-01
Deposition of new CENPA-containing nucleosomes at the centromere	33	7.05e-02	1.82e-01	2.47e-01
Nucleosome assembly	33	7.05e-02	1.82e-01	2.47e-01
TP53 Regulates Transcription of DNA Repair Genes	61	7.10e-02	-1.34e-01	2.48e-01
Other interleukin signaling	22	7.34e-02	-2.20e-01	2.56e-01
RNA Polymerase I Transcription Initiation	47	7.40e-02	-1.51e-01	2.58e-01
p130Cas linkage to MAPK signaling for integrins	12	7.50e-02	-2.97e-01	2.60e-01
RHO GTPases Activate WASPs and WAVEs	36	7.51e-02	-1.71e-01	2.60e-01
Hemostasis	537	7.56e-02	-4.49e-02	2.61e-01
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)	25	7.56e-02	2.05e-01	2.61e-01
Metabolism of water-soluble vitamins and cofactors	112	7.70e-02	-9.68e-02	2.65e-01
CLEC7A (Dectin-1) signaling	97	7.72e-02	-1.04e-01	2.65e-01
RHOF GTPase cycle	39	7.76e-02	-1.63e-01	2.66e-01
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters	20	7.78e-02	-2.28e-01	2.66e-01
Golgi Associated Vesicle Biogenesis	54	7.92e-02	-1.38e-01	2.69e-01
Retinoid metabolism and transport	31	7.92e-02	-1.82e-01	2.69e-01
CREB1 phosphorylation through the activation of Adenylate Cyclase	10	7.96e-02	3.20e-01	2.70e-01
Transcriptional regulation of white adipocyte differentiation	83	8.02e-02	-1.11e-01	2.71e-01
Collagen biosynthesis and modifying enzymes	61	8.19e-02	-1.29e-01	2.77e-01
Mitochondrial tRNA aminoacylation	21	8.24e-02	-2.19e-01	2.77e-01
RHOU GTPase cycle	39	8.25e-02	-1.61e-01	2.77e-01
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)	13	8.45e-02	-2.76e-01	2.83e-01
Polymerase switching on the C-strand of the telomere	26	8.49e-02	-1.95e-01	2.84e-01
S Phase	155	8.57e-02	-8.00e-02	2.86e-01
G1/S Transition	126	8.62e-02	-8.85e-02	2.87e-01
The role of Nef in HIV-1 replication and disease pathogenesis	27	8.63e-02	-1.91e-01	2.87e-01
Estrogen-dependent gene expression	97	8.66e-02	1.01e-01	2.87e-01
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	12	8.69e-02	2.85e-01	2.87e-01
Chaperone Mediated Autophagy	20	8.83e-02	-2.20e-01	2.91e-01
E2F mediated regulation of DNA replication	21	8.93e-02	2.14e-01	2.94e-01
MAPK3 (ERK1) activation	10	8.94e-02	3.10e-01	2.94e-01
mRNA 3’-end processing	56	9.00e-02	-1.31e-01	2.94e-01
DAP12 interactions	37	9.00e-02	1.61e-01	2.94e-01
Peroxisomal lipid metabolism	28	9.02e-02	-1.85e-01	2.94e-01
Recruitment of NuMA to mitotic centrosomes	79	9.07e-02	-1.10e-01	2.94e-01
IRAK4 deficiency (TLR2/4)	15	9.08e-02	2.52e-01	2.94e-01
PRC2 methylates histones and DNA	23	9.08e-02	2.04e-01	2.94e-01
Condensation of Prophase Chromosomes	23	9.27e-02	2.03e-01	3.00e-01
DARPP-32 events	23	9.38e-02	2.02e-01	3.03e-01
Transport of bile salts and organic acids, metal ions and amine compounds	55	9.44e-02	1.30e-01	3.04e-01
Metabolism of lipids	637	9.47e-02	-3.89e-02	3.04e-01
TP53 Regulates Transcription of Caspase Activators and Caspases	11	9.49e-02	2.91e-01	3.04e-01
Signal transduction by L1	21	9.53e-02	-2.10e-01	3.04e-01
cGMP effects	15	9.55e-02	2.49e-01	3.04e-01
Downstream signaling events of B Cell Receptor (BCR)	79	9.56e-02	-1.08e-01	3.04e-01
Neutrophil degranulation	451	9.64e-02	-4.57e-02	3.05e-01
Purine catabolism	15	9.64e-02	-2.48e-01	3.05e-01
Biotin transport and metabolism	11	9.65e-02	-2.89e-01	3.05e-01
Interleukin-1 signaling	99	9.75e-02	-9.64e-02	3.08e-01
Deubiquitination	236	9.77e-02	-6.26e-02	3.08e-01
ERKs are inactivated	13	9.83e-02	-2.65e-01	3.09e-01
Mismatch Repair	14	9.87e-02	-2.55e-01	3.09e-01
Interleukin-6 family signaling	20	9.88e-02	2.13e-01	3.09e-01
Cytochrome c-mediated apoptotic response	13	9.88e-02	2.64e-01	3.09e-01
Josephin domain DUBs	10	9.93e-02	-3.01e-01	3.09e-01
Mitotic G1 phase and G1/S transition	144	9.95e-02	-7.96e-02	3.09e-01
EPHA-mediated growth cone collapse	15	9.96e-02	-2.46e-01	3.09e-01
Signaling by PDGFR in disease	20	1.00e-01	2.12e-01	3.10e-01
Adenylate cyclase inhibitory pathway	12	1.01e-01	-2.74e-01	3.10e-01
Dual Incision in GG-NER	41	1.01e-01	-1.48e-01	3.10e-01
SIRT1 negatively regulates rRNA expression	18	1.01e-01	2.23e-01	3.10e-01
Resolution of AP sites via the multiple-nucleotide patch replacement pathway	25	1.01e-01	-1.89e-01	3.10e-01
Regulation of TP53 Activity through Phosphorylation	88	1.02e-01	1.01e-01	3.13e-01
Signaling by FGFR2	66	1.02e-01	-1.16e-01	3.13e-01
Removal of the Flap Intermediate from the C-strand	17	1.03e-01	-2.28e-01	3.14e-01
DNA Replication Pre-Initiation	92	1.04e-01	-9.82e-02	3.16e-01
C-type lectin receptors (CLRs)	124	1.04e-01	-8.46e-02	3.16e-01
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)	13	1.06e-01	-2.59e-01	3.21e-01
Diseases of DNA repair	32	1.08e-01	1.64e-01	3.27e-01
DCC mediated attractive signaling	13	1.09e-01	-2.57e-01	3.28e-01
DNA Replication	133	1.09e-01	-8.06e-02	3.28e-01
DNA methylation	14	1.10e-01	2.47e-01	3.30e-01
Neddylation	228	1.11e-01	-6.13e-02	3.33e-01
G alpha (12/13) signalling events	72	1.13e-01	-1.08e-01	3.37e-01
Translation of Replicase and Assembly of the Replication Transcription Complex	13	1.13e-01	-2.54e-01	3.39e-01
YAP1- and WWTR1 (TAZ)-stimulated gene expression	11	1.14e-01	2.75e-01	3.39e-01
Homologous DNA Pairing and Strand Exchange	41	1.14e-01	1.42e-01	3.40e-01
MyD88 deficiency (TLR2/4)	14	1.15e-01	2.44e-01	3.40e-01
Competing endogenous RNAs (ceRNAs) regulate PTEN translation	11	1.15e-01	2.74e-01	3.42e-01
Regulation of lipid metabolism by PPARalpha	109	1.17e-01	-8.70e-02	3.45e-01
Base Excision Repair	53	1.17e-01	-1.24e-01	3.47e-01
Cytosolic tRNA aminoacylation	24	1.19e-01	-1.84e-01	3.49e-01
Resolution of D-loop Structures through Holliday Junction Intermediates	31	1.19e-01	1.62e-01	3.49e-01
HATs acetylate histones	86	1.20e-01	-9.71e-02	3.49e-01
The activation of arylsulfatases	10	1.20e-01	-2.84e-01	3.49e-01
Metabolism of non-coding RNA	53	1.20e-01	-1.23e-01	3.49e-01
snRNP Assembly	53	1.20e-01	-1.23e-01	3.49e-01
HSF1 activation	26	1.20e-01	-1.76e-01	3.49e-01
Spry regulation of FGF signaling	16	1.21e-01	-2.24e-01	3.50e-01
mTORC1-mediated signalling	24	1.21e-01	-1.83e-01	3.50e-01
Synthesis of PIPs at the plasma membrane	51	1.21e-01	1.25e-01	3.50e-01
Beta-catenin independent WNT signaling	136	1.21e-01	-7.70e-02	3.50e-01
Synthesis of IP2, IP, and Ins in the cytosol	13	1.21e-01	2.48e-01	3.50e-01
Membrane binding and targetting of GAG proteins	14	1.24e-01	-2.38e-01	3.55e-01
Synthesis And Processing Of GAG, GAGPOL Polyproteins	14	1.24e-01	-2.38e-01	3.55e-01
Sphingolipid metabolism	77	1.25e-01	-1.01e-01	3.58e-01
FGFR2 mutant receptor activation	28	1.25e-01	-1.67e-01	3.58e-01
NRAGE signals death through JNK	56	1.29e-01	-1.17e-01	3.67e-01
Extension of Telomeres	49	1.30e-01	-1.25e-01	3.70e-01
DNA strand elongation	31	1.31e-01	-1.57e-01	3.71e-01
Recycling pathway of L1	25	1.31e-01	-1.74e-01	3.72e-01
Cellular Senescence	136	1.32e-01	7.48e-02	3.74e-01
Ion transport by P-type ATPases	44	1.34e-01	1.31e-01	3.77e-01
Calnexin/calreticulin cycle	26	1.34e-01	-1.70e-01	3.77e-01
Selective autophagy	60	1.35e-01	-1.12e-01	3.79e-01
Transport of vitamins, nucleosides, and related molecules	33	1.35e-01	-1.50e-01	3.80e-01
NOD1/2 Signaling Pathway	32	1.36e-01	1.52e-01	3.80e-01
Signaling by FGFR4 in disease	11	1.37e-01	2.59e-01	3.80e-01
Adherens junctions interactions	21	1.37e-01	1.87e-01	3.80e-01
Processing of Capped Intronless Pre-mRNA	28	1.37e-01	-1.62e-01	3.80e-01
Cohesin Loading onto Chromatin	10	1.38e-01	2.71e-01	3.80e-01
MAP2K and MAPK activation	35	1.38e-01	-1.45e-01	3.80e-01
Interleukin-2 family signaling	36	1.38e-01	1.43e-01	3.80e-01
Activation of G protein gated Potassium channels	19	1.38e-01	1.96e-01	3.80e-01
G protein gated Potassium channels	19	1.38e-01	1.96e-01	3.80e-01
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	19	1.38e-01	1.96e-01	3.80e-01
tRNA processing in the mitochondrion	27	1.39e-01	1.65e-01	3.80e-01
Signaling by FGFR3 fusions in cancer	10	1.39e-01	2.70e-01	3.80e-01
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template	37	1.39e-01	-1.41e-01	3.80e-01
SARS-CoV-1 Infection	49	1.39e-01	-1.22e-01	3.81e-01
Nucleotide biosynthesis	12	1.40e-01	-2.46e-01	3.81e-01
Chondroitin sulfate biosynthesis	17	1.41e-01	-2.06e-01	3.84e-01
Acetylcholine regulates insulin secretion	10	1.42e-01	2.68e-01	3.84e-01
Negative regulation of NMDA receptor-mediated neuronal transmission	18	1.42e-01	2.00e-01	3.84e-01
Estrogen-dependent nuclear events downstream of ESR-membrane signaling	22	1.42e-01	1.81e-01	3.85e-01
Translation of Structural Proteins	29	1.42e-01	-1.57e-01	3.85e-01
Glutathione conjugation	30	1.43e-01	-1.54e-01	3.86e-01
Potassium Channels	61	1.43e-01	1.08e-01	3.86e-01
PI-3K cascade:FGFR4	16	1.44e-01	2.11e-01	3.87e-01
TCF dependent signaling in response to WNT	165	1.45e-01	-6.57e-02	3.90e-01
Telomere Maintenance	73	1.46e-01	-9.85e-02	3.90e-01
Notch-HLH transcription pathway	28	1.47e-01	-1.58e-01	3.93e-01
O-linked glycosylation of mucins	44	1.47e-01	-1.26e-01	3.93e-01
Apoptotic execution phase	46	1.48e-01	1.23e-01	3.93e-01
Fatty acyl-CoA biosynthesis	34	1.48e-01	1.43e-01	3.93e-01
PCNA-Dependent Long Patch Base Excision Repair	21	1.48e-01	-1.82e-01	3.94e-01
Transcriptional regulation by RUNX3	95	1.50e-01	-8.55e-02	3.98e-01
STAT3 nuclear events downstream of ALK signaling	10	1.51e-01	2.62e-01	3.98e-01
Interleukin-3, Interleukin-5 and GM-CSF signaling	39	1.51e-01	1.33e-01	3.98e-01
Factors involved in megakaryocyte development and platelet production	109	1.51e-01	7.96e-02	3.98e-01
Deadenylation-dependent mRNA decay	53	1.52e-01	-1.14e-01	3.99e-01
Trafficking and processing of endosomal TLR	13	1.54e-01	-2.28e-01	4.04e-01
Signaling by CSF3 (G-CSF)	30	1.56e-01	1.50e-01	4.09e-01
EGR2 and SOX10-mediated initiation of Schwann cell myelination	25	1.56e-01	1.64e-01	4.09e-01
TP53 Regulates Transcription of Cell Cycle Genes	44	1.57e-01	1.23e-01	4.09e-01
Response of Mtb to phagocytosis	23	1.57e-01	-1.70e-01	4.09e-01
FGFR1 mutant receptor activation	27	1.57e-01	1.57e-01	4.09e-01
PI-3K cascade:FGFR1	16	1.58e-01	2.04e-01	4.10e-01
Activation of the AP-1 family of transcription factors	10	1.59e-01	2.57e-01	4.11e-01
SARS-CoV-2 Infection	70	1.59e-01	-9.74e-02	4.11e-01
Transport of Mature mRNAs Derived from Intronless Transcripts	43	1.60e-01	-1.24e-01	4.13e-01
VEGFA-VEGFR2 Pathway	94	1.61e-01	-8.38e-02	4.14e-01
Transport of Mature mRNA derived from an Intron-Containing Transcript	72	1.61e-01	-9.56e-02	4.14e-01
Synthesis of very long-chain fatty acyl-CoAs	22	1.61e-01	1.73e-01	4.14e-01
GRB2:SOS provides linkage to MAPK signaling for Integrins	12	1.61e-01	-2.33e-01	4.14e-01
Signaling by VEGF	103	1.63e-01	-7.96e-02	4.16e-01
Signaling by FGFR3 in disease	19	1.63e-01	1.85e-01	4.16e-01
Signaling by FGFR3 point mutants in cancer	19	1.63e-01	1.85e-01	4.16e-01
ERBB2 Regulates Cell Motility	13	1.64e-01	2.23e-01	4.17e-01
Removal of the Flap Intermediate	14	1.65e-01	-2.14e-01	4.20e-01
Inactivation of CSF3 (G-CSF) signaling	25	1.66e-01	1.60e-01	4.21e-01
ERBB2 Activates PTK6 Signaling	11	1.66e-01	2.41e-01	4.21e-01
PKMTs methylate histone lysines	43	1.67e-01	-1.22e-01	4.23e-01
MET activates RAP1 and RAC1	11	1.68e-01	2.40e-01	4.23e-01
Telomere C-strand (Lagging Strand) Synthesis	34	1.68e-01	-1.37e-01	4.23e-01
KSRP (KHSRP) binds and destabilizes mRNA	17	1.68e-01	-1.93e-01	4.23e-01
Apoptosis	167	1.68e-01	-6.18e-02	4.23e-01
Processive synthesis on the lagging strand	15	1.70e-01	-2.05e-01	4.26e-01
Interleukin-7 signaling	21	1.72e-01	1.72e-01	4.31e-01
Integrin cell surface interactions	61	1.73e-01	1.01e-01	4.32e-01
Downstream signaling of activated FGFR1	26	1.73e-01	1.54e-01	4.33e-01
Activation of PPARGC1A (PGC-1alpha) by phosphorylation	10	1.75e-01	2.48e-01	4.36e-01
G0 and Early G1	26	1.76e-01	1.53e-01	4.38e-01
MAP3K8 (TPL2)-dependent MAPK1/3 activation	16	1.76e-01	-1.95e-01	4.38e-01
Toll Like Receptor 4 (TLR4) Cascade	127	1.77e-01	6.94e-02	4.39e-01
Termination of translesion DNA synthesis	31	1.79e-01	-1.39e-01	4.44e-01
Formation of apoptosome	11	1.80e-01	2.34e-01	4.44e-01
Regulation of the apoptosome activity	11	1.80e-01	2.34e-01	4.44e-01
PPARA activates gene expression	107	1.80e-01	-7.50e-02	4.44e-01
Sema4D in semaphorin signaling	24	1.82e-01	-1.57e-01	4.47e-01
MTOR signalling	41	1.83e-01	-1.20e-01	4.48e-01
Downstream signaling of activated FGFR4	23	1.84e-01	1.60e-01	4.50e-01
RHOD GTPase cycle	51	1.85e-01	-1.07e-01	4.51e-01
Translesion Synthesis by POLH	18	1.86e-01	-1.80e-01	4.53e-01
Constitutive Signaling by Aberrant PI3K in Cancer	65	1.87e-01	9.47e-02	4.56e-01
Other semaphorin interactions	19	1.91e-01	1.73e-01	4.64e-01
Cell Cycle	592	1.91e-01	-3.15e-02	4.64e-01
EML4 and NUDC in mitotic spindle formation	88	1.93e-01	8.04e-02	4.67e-01
Transferrin endocytosis and recycling	29	1.95e-01	-1.39e-01	4.72e-01
Cilium Assembly	178	1.96e-01	-5.63e-02	4.73e-01
SUMOylation of immune response proteins	11	1.96e-01	-2.25e-01	4.73e-01
Transport of Mature mRNA Derived from an Intronless Transcript	42	1.97e-01	-1.15e-01	4.75e-01
Regulation of TNFR1 signaling	35	1.99e-01	-1.25e-01	4.79e-01
Defective pyroptosis	23	2.00e-01	1.55e-01	4.79e-01
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways	52	2.01e-01	1.03e-01	4.82e-01
Processing of Intronless Pre-mRNAs	19	2.01e-01	-1.69e-01	4.82e-01
Regulation of TLR by endogenous ligand	15	2.02e-01	1.90e-01	4.83e-01
Semaphorin interactions	63	2.03e-01	-9.28e-02	4.83e-01
SHC-mediated cascade:FGFR4	16	2.03e-01	1.84e-01	4.84e-01
Resolution of D-Loop Structures	32	2.04e-01	1.30e-01	4.86e-01
ABC transporters in lipid homeostasis	14	2.06e-01	1.95e-01	4.89e-01
Glyoxylate metabolism and glycine degradation	26	2.07e-01	1.43e-01	4.89e-01
HCMV Late Events	63	2.08e-01	-9.17e-02	4.92e-01
Signaling by Nuclear Receptors	221	2.09e-01	4.91e-02	4.93e-01
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal	84	2.10e-01	7.92e-02	4.93e-01
Amplification of signal from the kinetochores	84	2.10e-01	7.92e-02	4.93e-01
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	31	2.11e-01	1.30e-01	4.95e-01
Processive synthesis on the C-strand of the telomere	19	2.12e-01	-1.65e-01	4.98e-01
Cristae formation	31	2.13e-01	-1.29e-01	4.99e-01
Signaling by WNT	251	2.13e-01	-4.56e-02	4.99e-01
RHOA GTPase cycle	143	2.14e-01	-6.02e-02	5.00e-01
Signaling by PDGF	50	2.14e-01	-1.02e-01	5.00e-01
Peptide hormone metabolism	62	2.15e-01	9.10e-02	5.01e-01
PINK1-PRKN Mediated Mitophagy	21	2.16e-01	-1.56e-01	5.02e-01
Signaling by NOTCH	183	2.19e-01	-5.28e-02	5.07e-01
Cell-cell junction organization	42	2.20e-01	1.09e-01	5.09e-01
PIWI-interacting RNA (piRNA) biogenesis	22	2.20e-01	-1.51e-01	5.09e-01
Pre-NOTCH Transcription and Translation	43	2.21e-01	1.08e-01	5.09e-01
SHC-mediated cascade:FGFR1	16	2.22e-01	1.77e-01	5.09e-01
Intraflagellar transport	39	2.22e-01	-1.13e-01	5.09e-01
Signaling by FGFR	79	2.22e-01	-7.96e-02	5.09e-01
Uptake and actions of bacterial toxins	26	2.22e-01	-1.38e-01	5.09e-01
Interaction between L1 and Ankyrins	26	2.23e-01	1.38e-01	5.09e-01
Degradation of the extracellular matrix	90	2.23e-01	-7.43e-02	5.09e-01
Defective Intrinsic Pathway for Apoptosis	23	2.23e-01	-1.47e-01	5.09e-01
Signaling by Erythropoietin	24	2.23e-01	1.44e-01	5.09e-01
Transport of small molecules	576	2.24e-01	-2.97e-02	5.10e-01
Adaptive Immune System	724	2.27e-01	-2.65e-02	5.15e-01
PI-3K cascade:FGFR3	15	2.27e-01	1.80e-01	5.16e-01
Clathrin-mediated endocytosis	133	2.29e-01	-6.05e-02	5.17e-01
Synthesis of IP3 and IP4 in the cytosol	23	2.29e-01	1.45e-01	5.17e-01
RNA Polymerase I Transcription Termination	30	2.29e-01	-1.27e-01	5.17e-01
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	92	2.30e-01	7.24e-02	5.17e-01
Regulation of PTEN gene transcription	60	2.30e-01	-8.96e-02	5.17e-01
Activation of AMPK downstream of NMDARs	10	2.30e-01	2.19e-01	5.17e-01
Glycogen storage diseases	15	2.30e-01	-1.79e-01	5.17e-01
Effects of PIP2 hydrolysis	24	2.31e-01	1.41e-01	5.18e-01
Amyloid fiber formation	46	2.31e-01	-1.02e-01	5.18e-01
Regulation of IFNG signaling	13	2.32e-01	1.91e-01	5.18e-01
TP53 Regulates Transcription of Death Receptors and Ligands	11	2.32e-01	2.08e-01	5.18e-01
Translesion synthesis by REV1	16	2.33e-01	-1.72e-01	5.20e-01
Extra-nuclear estrogen signaling	65	2.34e-01	8.54e-02	5.21e-01
Signaling by ALK	26	2.34e-01	1.35e-01	5.21e-01
Mitotic Telophase/Cytokinesis	12	2.35e-01	1.98e-01	5.22e-01
GAB1 signalosome	15	2.37e-01	1.76e-01	5.24e-01
G2/M Checkpoints	128	2.38e-01	-6.04e-02	5.26e-01
Gastrin-CREB signalling pathway via PKC and MAPK	16	2.39e-01	1.70e-01	5.28e-01
Myogenesis	25	2.41e-01	1.36e-01	5.30e-01
Meiotic recombination	30	2.42e-01	1.23e-01	5.33e-01
Tie2 Signaling	17	2.43e-01	1.64e-01	5.34e-01
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	14	2.44e-01	-1.80e-01	5.34e-01
Carboxyterminal post-translational modifications of tubulin	32	2.44e-01	-1.19e-01	5.34e-01
Loss of Nlp from mitotic centrosomes	68	2.44e-01	-8.17e-02	5.34e-01
Loss of proteins required for interphase microtubule organization from the centrosome	68	2.44e-01	-8.17e-02	5.34e-01
Sema4D induced cell migration and growth-cone collapse	20	2.47e-01	-1.50e-01	5.35e-01
MyD88:MAL(TIRAP) cascade initiated on plasma membrane	97	2.47e-01	6.81e-02	5.35e-01
Toll Like Receptor 2 (TLR2) Cascade	97	2.47e-01	6.81e-02	5.35e-01
Toll Like Receptor TLR1:TLR2 Cascade	97	2.47e-01	6.81e-02	5.35e-01
Toll Like Receptor TLR6:TLR2 Cascade	97	2.47e-01	6.81e-02	5.35e-01
RA biosynthesis pathway	16	2.47e-01	-1.67e-01	5.36e-01
Synthesis of glycosylphosphatidylinositol (GPI)	18	2.48e-01	-1.57e-01	5.36e-01
Post-chaperonin tubulin folding pathway	18	2.50e-01	-1.57e-01	5.40e-01
Metabolism of Angiotensinogen to Angiotensins	16	2.51e-01	-1.66e-01	5.40e-01
MAPK targets/ Nuclear events mediated by MAP kinases	31	2.51e-01	1.19e-01	5.40e-01
Translesion synthesis by POLI	17	2.53e-01	-1.60e-01	5.44e-01
FRS-mediated FGFR4 signaling	18	2.53e-01	1.55e-01	5.44e-01
Recognition of DNA damage by PCNA-containing replication complex	29	2.56e-01	-1.22e-01	5.49e-01
Programmed Cell Death	194	2.58e-01	-4.71e-02	5.51e-01
Mitotic Spindle Checkpoint	100	2.58e-01	6.55e-02	5.51e-01
Amino acid transport across the plasma membrane	26	2.59e-01	1.28e-01	5.53e-01
SUMOylation of transcription cofactors	44	2.59e-01	-9.83e-02	5.53e-01
Receptor Mediated Mitophagy	11	2.63e-01	-1.95e-01	5.57e-01
Signaling by BMP	24	2.63e-01	1.32e-01	5.57e-01
Regulation of MECP2 expression and activity	30	2.63e-01	1.18e-01	5.57e-01
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism	11	2.63e-01	-1.95e-01	5.57e-01
tRNA processing	131	2.64e-01	-5.66e-02	5.57e-01
Phase II - Conjugation of compounds	70	2.64e-01	-7.72e-02	5.57e-01
Constitutive Signaling by EGFRvIII	15	2.65e-01	1.66e-01	5.57e-01
Signaling by EGFRvIII in Cancer	15	2.65e-01	1.66e-01	5.57e-01
Downstream signaling of activated FGFR3	22	2.67e-01	1.37e-01	5.62e-01
Glycolysis	67	2.70e-01	-7.80e-02	5.66e-01
Lagging Strand Synthesis	20	2.72e-01	-1.42e-01	5.70e-01
Ovarian tumor domain proteases	38	2.73e-01	-1.03e-01	5.70e-01
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	15	2.73e-01	1.63e-01	5.70e-01
FRS-mediated FGFR1 signaling	18	2.73e-01	1.49e-01	5.70e-01
Free fatty acids regulate insulin secretion	10	2.73e-01	2.00e-01	5.70e-01
Potential therapeutics for SARS	84	2.76e-01	-6.88e-02	5.74e-01
MAPK family signaling cascades	290	2.78e-01	3.70e-02	5.76e-01
HIV Transcription Initiation	45	2.79e-01	-9.32e-02	5.76e-01
RNA Polymerase II HIV Promoter Escape	45	2.79e-01	-9.32e-02	5.76e-01
RNA Polymerase II Promoter Escape	45	2.79e-01	-9.32e-02	5.76e-01
RNA Polymerase II Transcription Initiation	45	2.79e-01	-9.32e-02	5.76e-01
RNA Polymerase II Transcription Initiation And Promoter Clearance	45	2.79e-01	-9.32e-02	5.76e-01
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening	45	2.79e-01	-9.32e-02	5.76e-01
Opioid Signalling	80	2.80e-01	6.99e-02	5.76e-01
Immune System	1752	2.81e-01	-1.56e-02	5.78e-01
DNA Double Strand Break Response	46	2.82e-01	-9.18e-02	5.78e-01
Cargo concentration in the ER	30	2.83e-01	1.13e-01	5.79e-01
Caspase-mediated cleavage of cytoskeletal proteins	12	2.86e-01	-1.78e-01	5.84e-01
Dissolution of Fibrin Clot	11	2.87e-01	-1.85e-01	5.84e-01
Signaling by Rho GTPases, Miro GTPases and RHOBTB3	611	2.87e-01	-2.53e-02	5.84e-01
Regulation of PLK1 Activity at G2/M Transition	86	2.87e-01	-6.64e-02	5.84e-01
RHO GTPases activate PAKs	21	2.87e-01	-1.34e-01	5.84e-01
Glucose metabolism	85	2.88e-01	-6.67e-02	5.84e-01
Gap junction degradation	10	2.88e-01	-1.94e-01	5.84e-01
AURKA Activation by TPX2	70	2.88e-01	-7.34e-02	5.84e-01
ATF6 (ATF6-alpha) activates chaperone genes	10	2.89e-01	-1.94e-01	5.85e-01
Beta-oxidation of very long chain fatty acids	11	2.90e-01	-1.84e-01	5.86e-01
Unwinding of DNA	11	2.91e-01	-1.84e-01	5.86e-01
Signaling by Hippo	20	2.91e-01	1.36e-01	5.86e-01
Antiviral mechanism by IFN-stimulated genes	80	2.91e-01	6.83e-02	5.86e-01
Collagen degradation	31	2.91e-01	-1.09e-01	5.86e-01
Platelet activation, signaling and aggregation	228	2.92e-01	-4.05e-02	5.86e-01
Cytosolic sulfonation of small molecules	19	2.93e-01	-1.39e-01	5.86e-01
Integrin signaling	24	2.93e-01	-1.24e-01	5.87e-01
O-glycosylation of TSR domain-containing proteins	37	2.94e-01	-9.97e-02	5.88e-01
HDACs deacetylate histones	39	2.95e-01	-9.69e-02	5.89e-01
Transcriptional regulation by RUNX1	179	2.96e-01	-4.53e-02	5.90e-01
Intra-Golgi traffic	42	2.97e-01	-9.31e-02	5.91e-01
Fanconi Anemia Pathway	35	2.98e-01	-1.02e-01	5.92e-01
Signaling by EGFR in Cancer	23	2.98e-01	1.25e-01	5.92e-01
EPH-ephrin mediated repulsion of cells	44	3.00e-01	-9.03e-02	5.94e-01
Oxidative Stress Induced Senescence	73	3.00e-01	7.02e-02	5.94e-01
Nucleotide-like (purinergic) receptors	15	3.02e-01	1.54e-01	5.97e-01
Apoptotic cleavage of cellular proteins	36	3.02e-01	9.93e-02	5.97e-01
Interleukin-1 family signaling	127	3.03e-01	-5.30e-02	5.97e-01
RHO GTPase cycle	426	3.03e-01	-2.91e-02	5.97e-01
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism	13	3.04e-01	-1.65e-01	5.97e-01
alpha-linolenic acid (ALA) metabolism	13	3.04e-01	-1.65e-01	5.97e-01
Pyrimidine salvage	10	3.05e-01	-1.87e-01	5.98e-01
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	25	3.07e-01	-1.18e-01	6.01e-01
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	47	3.08e-01	8.59e-02	6.01e-01
ATF6 (ATF6-alpha) activates chaperones	12	3.09e-01	-1.70e-01	6.01e-01
Cholesterol biosynthesis	25	3.10e-01	-1.17e-01	6.01e-01
Prolactin receptor signaling	10	3.10e-01	-1.85e-01	6.01e-01
Signaling by Rho GTPases	596	3.11e-01	-2.44e-02	6.01e-01
SHC-mediated cascade:FGFR3	15	3.12e-01	1.51e-01	6.01e-01
Glutamate and glutamine metabolism	12	3.12e-01	-1.69e-01	6.01e-01
ADP signalling through P2Y purinoceptor 1	20	3.12e-01	1.31e-01	6.01e-01
PIP3 activates AKT signaling	253	3.13e-01	-3.69e-02	6.01e-01
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases	14	3.13e-01	-1.56e-01	6.01e-01
Platelet Aggregation (Plug Formation)	31	3.13e-01	-1.05e-01	6.01e-01
Metabolic disorders of biological oxidation enzymes	24	3.14e-01	-1.19e-01	6.01e-01
Aggrephagy	22	3.14e-01	-1.24e-01	6.01e-01
N-glycan antennae elongation in the medial/trans-Golgi	21	3.15e-01	-1.27e-01	6.01e-01
Cell recruitment (pro-inflammatory response)	24	3.16e-01	-1.18e-01	6.01e-01
Purinergic signaling in leishmaniasis infection	24	3.16e-01	-1.18e-01	6.01e-01
Activation of kainate receptors upon glutamate binding	23	3.16e-01	1.21e-01	6.01e-01
Endosomal/Vacuolar pathway	11	3.16e-01	1.75e-01	6.01e-01
Signaling by NODAL	15	3.16e-01	-1.49e-01	6.01e-01
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects	17	3.17e-01	1.40e-01	6.01e-01
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)	17	3.17e-01	1.40e-01	6.01e-01
NF-kB is activated and signals survival	13	3.17e-01	-1.60e-01	6.01e-01
G2/M DNA damage checkpoint	60	3.17e-01	7.47e-02	6.01e-01
Assembly of collagen fibrils and other multimeric structures	52	3.17e-01	-8.02e-02	6.01e-01
Metabolism of nucleotides	89	3.17e-01	-6.13e-02	6.01e-01
Infection with Mycobacterium tuberculosis	27	3.19e-01	-1.11e-01	6.04e-01
Peroxisomal protein import	60	3.20e-01	-7.43e-02	6.04e-01
M Phase	344	3.20e-01	-3.12e-02	6.04e-01
Cell Cycle, Mitotic	480	3.20e-01	-2.65e-02	6.04e-01
Nephrin family interactions	19	3.23e-01	-1.31e-01	6.08e-01
FGFR3 ligand binding and activation	10	3.25e-01	1.80e-01	6.09e-01
FGFR3c ligand binding and activation	10	3.25e-01	1.80e-01	6.09e-01
Regulation of localization of FOXO transcription factors	11	3.26e-01	-1.71e-01	6.11e-01
TNF signaling	44	3.26e-01	-8.55e-02	6.11e-01
Signaling by high-kinase activity BRAF mutants	31	3.27e-01	-1.02e-01	6.11e-01
Formation of Incision Complex in GG-NER	43	3.28e-01	-8.63e-02	6.12e-01
Basigin interactions	21	3.28e-01	-1.23e-01	6.12e-01
Intracellular signaling by second messengers	290	3.29e-01	-3.34e-02	6.12e-01
Arachidonic acid metabolism	38	3.29e-01	-9.14e-02	6.13e-01
Synthesis of bile acids and bile salts	29	3.30e-01	1.04e-01	6.14e-01
G-protein activation	18	3.33e-01	1.32e-01	6.18e-01
Negative regulation of TCF-dependent signaling by WNT ligand antagonists	10	3.33e-01	-1.77e-01	6.18e-01
Signaling by NTRK1 (TRKA)	109	3.37e-01	5.33e-02	6.23e-01
Acyl chain remodelling of PI	11	3.37e-01	-1.67e-01	6.24e-01
RNA polymerase II transcribes snRNA genes	71	3.39e-01	-6.57e-02	6.25e-01
Visual phototransduction	63	3.40e-01	-6.95e-02	6.28e-01
Regulation of TP53 Activity through Methylation	19	3.41e-01	-1.26e-01	6.28e-01
MET receptor recycling	10	3.42e-01	1.73e-01	6.29e-01
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	45	3.43e-01	-8.18e-02	6.29e-01
Negative regulation of the PI3K/AKT network	99	3.44e-01	5.51e-02	6.29e-01
RNA Polymerase I Promoter Clearance	60	3.44e-01	-7.07e-02	6.29e-01
RNA Polymerase I Transcription	60	3.44e-01	-7.07e-02	6.29e-01
Interactions of Rev with host cellular proteins	37	3.45e-01	-8.98e-02	6.30e-01
PI3K/AKT Signaling in Cancer	92	3.46e-01	5.69e-02	6.31e-01
Glutamate binding, activation of AMPA receptors and synaptic plasticity	26	3.46e-01	1.07e-01	6.31e-01
Trafficking of AMPA receptors	26	3.46e-01	1.07e-01	6.31e-01
Transcriptional activation of mitochondrial biogenesis	53	3.48e-01	7.46e-02	6.32e-01
Signaling by ERBB2 ECD mutants	16	3.51e-01	1.35e-01	6.36e-01
DNA Double-Strand Break Repair	132	3.51e-01	-4.71e-02	6.36e-01
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand	37	3.51e-01	-8.86e-02	6.36e-01
PI Metabolism	79	3.52e-01	6.06e-02	6.37e-01
Initiation of Nuclear Envelope (NE) Reformation	19	3.53e-01	1.23e-01	6.38e-01
Dectin-2 family	14	3.54e-01	-1.43e-01	6.39e-01
Pexophagy	11	3.55e-01	-1.61e-01	6.40e-01
Negative regulation of FGFR2 signaling	29	3.55e-01	-9.92e-02	6.40e-01
Interleukin-2 signaling	11	3.58e-01	1.60e-01	6.43e-01
Phosphorylation of CD3 and TCR zeta chains	22	3.58e-01	1.13e-01	6.43e-01
DNA Damage Bypass	45	3.59e-01	-7.91e-02	6.43e-01
Regulation of signaling by CBL	18	3.59e-01	1.25e-01	6.43e-01
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)	32	3.61e-01	-9.33e-02	6.44e-01
Regulation of Glucokinase by Glucokinase Regulatory Protein	32	3.61e-01	-9.33e-02	6.44e-01
Gap junction trafficking and regulation	18	3.61e-01	-1.24e-01	6.44e-01
VEGFR2 mediated vascular permeability	27	3.62e-01	-1.01e-01	6.46e-01
Keratan sulfate/keratin metabolism	29	3.63e-01	-9.76e-02	6.46e-01
Smooth Muscle Contraction	34	3.65e-01	-8.99e-02	6.49e-01
NCAM1 interactions	29	3.69e-01	9.65e-02	6.54e-01
Respiratory electron transport	103	3.69e-01	5.13e-02	6.54e-01
Assembly and cell surface presentation of NMDA receptors	23	3.70e-01	1.08e-01	6.56e-01
Rev-mediated nuclear export of HIV RNA	35	3.71e-01	-8.74e-02	6.56e-01
Regulated Necrosis	54	3.72e-01	7.02e-02	6.57e-01
FRS-mediated FGFR3 signaling	17	3.72e-01	1.25e-01	6.57e-01
CD28 dependent PI3K/Akt signaling	21	3.73e-01	-1.12e-01	6.57e-01
Platelet Adhesion to exposed collagen	10	3.74e-01	1.63e-01	6.58e-01
Inactivation, recovery and regulation of the phototransduction cascade	21	3.75e-01	1.12e-01	6.59e-01
Toll Like Receptor 9 (TLR9) Cascade	94	3.76e-01	5.29e-02	6.61e-01
Downstream signal transduction	28	3.77e-01	-9.64e-02	6.62e-01
PI-3K cascade:FGFR2	18	3.78e-01	1.20e-01	6.63e-01
Phase 4 - resting membrane potential	11	3.79e-01	1.53e-01	6.63e-01
DAP12 signaling	28	3.80e-01	9.58e-02	6.64e-01
Signaling by cytosolic FGFR1 fusion mutants	18	3.81e-01	1.19e-01	6.64e-01
RIPK1-mediated regulated necrosis	29	3.81e-01	9.40e-02	6.64e-01
Regulation of necroptotic cell death	29	3.81e-01	9.40e-02	6.64e-01
Constitutive Signaling by NOTCH1 HD Domain Mutants	15	3.84e-01	1.30e-01	6.67e-01
Signaling by NOTCH1 HD Domain Mutants in Cancer	15	3.84e-01	1.30e-01	6.67e-01
Elevation of cytosolic Ca2+ levels	13	3.84e-01	1.39e-01	6.67e-01
FGFR1 ligand binding and activation	11	3.84e-01	1.51e-01	6.67e-01
Signaling by FLT3 fusion proteins	19	3.85e-01	1.15e-01	6.67e-01
Toll Like Receptor 7/8 (TLR7/8) Cascade	91	3.86e-01	5.26e-02	6.67e-01
Processing of SMDT1	15	3.86e-01	-1.29e-01	6.68e-01
SLC transporter disorders	77	3.87e-01	-5.70e-02	6.68e-01
Organelle biogenesis and maintenance	270	3.89e-01	-3.05e-02	6.69e-01
Translesion synthesis by POLK	17	3.89e-01	-1.21e-01	6.69e-01
Meiosis	55	3.89e-01	6.71e-02	6.69e-01
RHO GTPases activate CIT	18	3.91e-01	-1.17e-01	6.69e-01
TICAM1-dependent activation of IRF3/IRF7	12	3.91e-01	-1.43e-01	6.69e-01
CDC42 GTPase cycle	149	3.92e-01	-4.07e-02	6.69e-01
Interleukin-27 signaling	10	3.92e-01	1.56e-01	6.69e-01
Depolymerisation of the Nuclear Lamina	15	3.92e-01	1.28e-01	6.69e-01
Downstream signaling of activated FGFR2	25	3.94e-01	9.86e-02	6.69e-01
LGI-ADAM interactions	10	3.94e-01	-1.56e-01	6.69e-01
Nuclear import of Rev protein	34	3.94e-01	-8.44e-02	6.69e-01
Disorders of Developmental Biology	13	3.96e-01	-1.36e-01	6.69e-01
Disorders of Nervous System Development	13	3.96e-01	-1.36e-01	6.69e-01
Loss of function of MECP2 in Rett syndrome	13	3.96e-01	-1.36e-01	6.69e-01
Pervasive developmental disorders	13	3.96e-01	-1.36e-01	6.69e-01
MyD88-independent TLR4 cascade	97	3.96e-01	4.99e-02	6.69e-01
TRIF(TICAM1)-mediated TLR4 signaling	97	3.96e-01	4.99e-02	6.69e-01
Packaging Of Telomere Ends	15	3.96e-01	1.27e-01	6.69e-01
Glutathione synthesis and recycling	11	3.97e-01	-1.48e-01	6.69e-01
Diseases associated with N-glycosylation of proteins	17	3.97e-01	-1.19e-01	6.69e-01
Zinc transporters	13	3.98e-01	-1.36e-01	6.69e-01
Acyl chain remodelling of PE	21	3.98e-01	-1.06e-01	6.70e-01
HCMV Early Events	67	3.99e-01	-5.95e-02	6.70e-01
Defective B3GALTL causes PpS	36	4.00e-01	-8.11e-02	6.70e-01
Surfactant metabolism	21	4.00e-01	-1.06e-01	6.70e-01
Mitotic Anaphase	215	4.00e-01	-3.33e-02	6.70e-01
p75NTR signals via NF-kB	16	4.02e-01	-1.21e-01	6.71e-01
Golgi Cisternae Pericentriolar Stack Reorganization	14	4.02e-01	-1.29e-01	6.71e-01
Leading Strand Synthesis	14	4.03e-01	-1.29e-01	6.71e-01
Polymerase switching	14	4.03e-01	-1.29e-01	6.71e-01
Attenuation phase	23	4.05e-01	-1.00e-01	6.73e-01
Toll Like Receptor 3 (TLR3) Cascade	93	4.06e-01	4.98e-02	6.75e-01
HDR through Single Strand Annealing (SSA)	36	4.07e-01	7.99e-02	6.75e-01
Nicotinate metabolism	28	4.08e-01	-9.03e-02	6.77e-01
RAF activation	34	4.10e-01	8.17e-02	6.79e-01
FGFR4 ligand binding and activation	10	4.11e-01	1.50e-01	6.80e-01
G beta:gamma signalling through PLC beta	15	4.12e-01	1.22e-01	6.81e-01
Transcriptional Regulation by E2F6	34	4.14e-01	8.10e-02	6.84e-01
MAPK6/MAPK4 signaling	85	4.14e-01	-5.12e-02	6.84e-01
mitochondrial fatty acid beta-oxidation of saturated fatty acids	10	4.16e-01	1.49e-01	6.85e-01
STING mediated induction of host immune responses	15	4.16e-01	-1.21e-01	6.85e-01
Antigen processing: Ubiquitination & Proteasome degradation	297	4.16e-01	-2.74e-02	6.85e-01
Transport of inorganic cations/anions and amino acids/oligopeptides	80	4.17e-01	5.25e-02	6.85e-01
Pre-NOTCH Expression and Processing	59	4.19e-01	6.09e-02	6.86e-01
Regulation of KIT signaling	16	4.19e-01	1.17e-01	6.86e-01
Metabolism of folate and pterines	17	4.19e-01	-1.13e-01	6.86e-01
TP53 Regulates Transcription of Cell Death Genes	41	4.20e-01	7.27e-02	6.86e-01
Synthesis of Leukotrienes (LT) and Eoxins (EX)	12	4.21e-01	-1.34e-01	6.86e-01
Signaling by PDGFRA extracellular domain mutants	12	4.22e-01	1.34e-01	6.86e-01
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants	12	4.22e-01	1.34e-01	6.86e-01
Interleukin-15 signaling	14	4.23e-01	1.24e-01	6.86e-01
Mitotic Metaphase and Anaphase	216	4.23e-01	-3.17e-02	6.86e-01
Keratinization	34	4.23e-01	7.94e-02	6.86e-01
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer’s disease models	20	4.24e-01	-1.03e-01	6.86e-01
Neurodegenerative Diseases	20	4.24e-01	-1.03e-01	6.86e-01
COPII-mediated vesicle transport	65	4.26e-01	-5.71e-02	6.90e-01
Class B/2 (Secretin family receptors)	63	4.27e-01	5.79e-02	6.90e-01
APC-Cdc20 mediated degradation of Nek2A	23	4.27e-01	-9.57e-02	6.90e-01
Negative regulation of FGFR3 signaling	26	4.29e-01	-8.97e-02	6.91e-01
The phototransduction cascade	22	4.30e-01	9.73e-02	6.92e-01
Generation of second messenger molecules	33	4.30e-01	7.94e-02	6.92e-01
TNFR1-induced NFkappaB signaling pathway	26	4.31e-01	-8.91e-02	6.93e-01
Bile acid and bile salt metabolism	33	4.32e-01	7.91e-02	6.93e-01
SUMOylation of DNA replication proteins	46	4.32e-01	-6.69e-02	6.93e-01
Triglyceride biosynthesis	11	4.33e-01	1.37e-01	6.93e-01
Signal Transduction	2100	4.33e-01	1.05e-02	6.93e-01
WNT ligand biogenesis and trafficking	18	4.34e-01	-1.07e-01	6.93e-01
TCR signaling	115	4.34e-01	-4.22e-02	6.93e-01
eNOS activation	11	4.35e-01	-1.36e-01	6.93e-01
Nuclear Envelope (NE) Reassembly	69	4.35e-01	-5.43e-02	6.93e-01
Telomere Extension By Telomerase	21	4.36e-01	-9.83e-02	6.93e-01
L1CAM interactions	92	4.36e-01	-4.70e-02	6.93e-01
Formation of ATP by chemiosmotic coupling	18	4.36e-01	-1.06e-01	6.93e-01
Signaling by ERBB4	51	4.37e-01	6.30e-02	6.93e-01
Formation of Senescence-Associated Heterochromatin Foci (SAHF)	12	4.38e-01	1.29e-01	6.94e-01
ER Quality Control Compartment (ERQC)	21	4.38e-01	-9.77e-02	6.94e-01
CaMK IV-mediated phosphorylation of CREB	10	4.39e-01	1.41e-01	6.94e-01
Ub-specific processing proteases	164	4.40e-01	-3.50e-02	6.94e-01
Downregulation of ERBB2:ERBB3 signaling	13	4.40e-01	-1.24e-01	6.94e-01
FOXO-mediated transcription of cell death genes	16	4.41e-01	-1.11e-01	6.95e-01
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon	17	4.41e-01	-1.08e-01	6.95e-01
Synthesis of active ubiquitin: roles of E1 and E2 enzymes	29	4.42e-01	8.25e-02	6.95e-01
RIP-mediated NFkB activation via ZBP1	17	4.42e-01	-1.08e-01	6.95e-01
Insulin receptor recycling	23	4.43e-01	-9.25e-02	6.95e-01
Gap junction trafficking	16	4.43e-01	-1.11e-01	6.95e-01
Regulation of RUNX1 Expression and Activity	18	4.48e-01	1.03e-01	7.02e-01
Norepinephrine Neurotransmitter Release Cycle	14	4.51e-01	-1.16e-01	7.06e-01
Signaling by Activin	14	4.54e-01	-1.16e-01	7.08e-01
Ion channel transport	140	4.54e-01	3.67e-02	7.08e-01
Meiotic synapsis	35	4.54e-01	7.31e-02	7.08e-01
Complex I biogenesis	57	4.55e-01	5.72e-02	7.08e-01
Constitutive Signaling by Overexpressed ERBB2	11	4.55e-01	1.30e-01	7.08e-01
RAS processing	19	4.56e-01	9.88e-02	7.08e-01
MET activates RAS signaling	11	4.60e-01	1.29e-01	7.15e-01
Cellular response to heat stress	97	4.61e-01	-4.34e-02	7.15e-01
Kinesins	34	4.63e-01	7.28e-02	7.15e-01
Senescence-Associated Secretory Phenotype (SASP)	59	4.63e-01	5.52e-02	7.15e-01
Presynaptic function of Kainate receptors	16	4.64e-01	1.06e-01	7.15e-01
Protein methylation	15	4.64e-01	-1.09e-01	7.15e-01
Nucleotide salvage	22	4.64e-01	-9.02e-02	7.15e-01
MyD88 dependent cascade initiated on endosome	90	4.65e-01	4.46e-02	7.15e-01
Mitochondrial calcium ion transport	22	4.65e-01	-9.01e-02	7.15e-01
Activation of gene expression by SREBF (SREBP)	42	4.67e-01	-6.49e-02	7.18e-01
RNA Polymerase I Promoter Opening	13	4.68e-01	1.16e-01	7.18e-01
Signal amplification	27	4.68e-01	8.07e-02	7.18e-01
Costimulation by the CD28 family	65	4.70e-01	-5.19e-02	7.20e-01
Synthesis of PIPs at the Golgi membrane	15	4.70e-01	-1.08e-01	7.20e-01
tRNA modification in the nucleus and cytosol	43	4.71e-01	-6.36e-02	7.20e-01
RAB GEFs exchange GTP for GDP on RABs	87	4.72e-01	-4.46e-02	7.21e-01
RHOB GTPase cycle	66	4.72e-01	-5.12e-02	7.21e-01
Acyl chain remodelling of PG	12	4.73e-01	-1.20e-01	7.21e-01
Tryptophan catabolism	11	4.73e-01	1.25e-01	7.21e-01
The citric acid (TCA) cycle and respiratory electron transport	173	4.74e-01	3.16e-02	7.21e-01
Regulation of cholesterol biosynthesis by SREBP (SREBF)	55	4.75e-01	-5.57e-02	7.22e-01
Transport of the SLBP Dependant Mature mRNA	36	4.76e-01	-6.87e-02	7.22e-01
ALK mutants bind TKIs	11	4.76e-01	1.24e-01	7.22e-01
Non-integrin membrane-ECM interactions	40	4.76e-01	-6.51e-02	7.22e-01
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.	126	4.77e-01	3.67e-02	7.22e-01
Anchoring of the basal body to the plasma membrane	96	4.79e-01	-4.19e-02	7.24e-01
SUMOylation of transcription factors	17	4.80e-01	-9.90e-02	7.25e-01
p75NTR recruits signalling complexes	13	4.81e-01	-1.13e-01	7.26e-01
Platelet sensitization by LDL	17	4.81e-01	9.86e-02	7.26e-01
Voltage gated Potassium channels	23	4.82e-01	8.47e-02	7.26e-01
SHC-mediated cascade:FGFR2	18	4.83e-01	9.56e-02	7.26e-01
Energy dependent regulation of mTOR by LKB1-AMPK	29	4.83e-01	-7.53e-02	7.26e-01
Thromboxane signalling through TP receptor	19	4.87e-01	9.22e-02	7.30e-01
Oncogenic MAPK signaling	74	4.87e-01	4.68e-02	7.30e-01
Acyl chain remodelling of PC	20	4.89e-01	-8.93e-02	7.33e-01
RHO GTPases Activate ROCKs	19	4.96e-01	-9.01e-02	7.42e-01
Glutamate Neurotransmitter Release Cycle	21	4.96e-01	8.57e-02	7.42e-01
HuR (ELAVL1) binds and stabilizes mRNA	10	4.97e-01	-1.24e-01	7.42e-01
Regulation of pyruvate dehydrogenase (PDH) complex	15	4.97e-01	1.01e-01	7.42e-01
RHOC GTPase cycle	69	4.98e-01	-4.72e-02	7.43e-01
Lewis blood group biosynthesis	12	4.99e-01	-1.13e-01	7.43e-01
Tight junction interactions	19	5.00e-01	8.95e-02	7.43e-01
Processing of DNA double-strand break ends	64	5.00e-01	4.88e-02	7.43e-01
Translocation of SLC2A4 (GLUT4) to the plasma membrane	50	5.00e-01	5.51e-02	7.43e-01
Diseases of mitotic cell cycle	37	5.03e-01	6.37e-02	7.46e-01
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	30	5.04e-01	-7.05e-02	7.46e-01
Generic Transcription Pathway	1103	5.05e-01	1.20e-02	7.46e-01
Formation of the beta-catenin:TCF transactivating complex	40	5.05e-01	6.10e-02	7.46e-01
Glycerophospholipid biosynthesis	109	5.05e-01	-3.70e-02	7.46e-01
Aberrant regulation of mitotic cell cycle due to RB1 defects	35	5.05e-01	6.51e-02	7.46e-01
Sensory Perception	147	5.08e-01	-3.16e-02	7.48e-01
Cargo recognition for clathrin-mediated endocytosis	95	5.09e-01	-3.92e-02	7.48e-01
Regulation of FZD by ubiquitination	17	5.09e-01	9.25e-02	7.48e-01
Prostacyclin signalling through prostacyclin receptor	14	5.09e-01	1.02e-01	7.48e-01
G beta:gamma signalling through CDC42	15	5.10e-01	9.84e-02	7.48e-01
Mitotic Prometaphase	177	5.10e-01	2.87e-02	7.48e-01
Signaling by SCF-KIT	42	5.13e-01	5.83e-02	7.51e-01
Signaling by ALK fusions and activated point mutants	54	5.14e-01	-5.14e-02	7.51e-01
Signaling by ALK in cancer	54	5.14e-01	-5.14e-02	7.51e-01
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	19	5.17e-01	8.59e-02	7.55e-01
Uptake and function of anthrax toxins	11	5.18e-01	-1.13e-01	7.55e-01
Nuclear Receptor transcription pathway	43	5.18e-01	5.70e-02	7.55e-01
Toll-like Receptor Cascades	148	5.19e-01	3.07e-02	7.55e-01
Pyruvate metabolism	27	5.20e-01	7.15e-02	7.55e-01
Signaling by EGFR	46	5.21e-01	5.47e-02	7.55e-01
Signaling by KIT in disease	20	5.21e-01	8.29e-02	7.55e-01
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants	20	5.21e-01	8.29e-02	7.55e-01
NOTCH3 Intracellular Domain Regulates Transcription	22	5.21e-01	7.90e-02	7.55e-01
Fatty acid metabolism	149	5.23e-01	-3.03e-02	7.57e-01
ADP signalling through P2Y purinoceptor 12	16	5.23e-01	9.22e-02	7.57e-01
GABA receptor activation	38	5.25e-01	5.96e-02	7.58e-01
G beta:gamma signalling through BTK	13	5.27e-01	1.01e-01	7.61e-01
SUMOylation of intracellular receptors	27	5.28e-01	7.02e-02	7.61e-01
Reproduction	66	5.29e-01	4.48e-02	7.62e-01
Signaling by Retinoic Acid	36	5.30e-01	-6.05e-02	7.62e-01
RHO GTPase Effectors	234	5.31e-01	-2.38e-02	7.62e-01
Interleukin-12 signaling	41	5.31e-01	-5.66e-02	7.62e-01
Regulated proteolysis of p75NTR	11	5.31e-01	-1.09e-01	7.62e-01
Receptor-type tyrosine-protein phosphatases	15	5.31e-01	9.34e-02	7.62e-01
ZBP1(DAI) mediated induction of type I IFNs	20	5.32e-01	-8.07e-02	7.62e-01
Condensation of Prometaphase Chromosomes	11	5.33e-01	1.09e-01	7.62e-01
Suppression of phagosomal maturation	13	5.33e-01	-9.98e-02	7.62e-01
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	32	5.34e-01	-6.36e-02	7.62e-01
Class I MHC mediated antigen processing & presentation	361	5.36e-01	-1.90e-02	7.64e-01
Interleukin-35 Signalling	11	5.36e-01	1.08e-01	7.64e-01
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1	16	5.36e-01	8.93e-02	7.64e-01
Disassembly of the destruction complex and recruitment of AXIN to the membrane	27	5.39e-01	-6.82e-02	7.66e-01
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	34	5.40e-01	-6.08e-02	7.66e-01
PKA activation in glucagon signalling	15	5.40e-01	-9.13e-02	7.66e-01
FRS-mediated FGFR2 signaling	20	5.40e-01	7.91e-02	7.66e-01
BMAL1:CLOCK,NPAS2 activates circadian gene expression	26	5.42e-01	6.91e-02	7.67e-01
Deadenylation of mRNA	22	5.43e-01	-7.48e-02	7.67e-01
RHO GTPases Activate NADPH Oxidases	21	5.44e-01	7.65e-02	7.67e-01
Glycogen breakdown (glycogenolysis)	15	5.45e-01	9.04e-02	7.67e-01
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	89	5.45e-01	3.72e-02	7.67e-01
RHOV GTPase cycle	35	5.45e-01	-5.92e-02	7.67e-01
Phospholipase C-mediated cascade; FGFR4	11	5.45e-01	1.05e-01	7.67e-01
Heme biosynthesis	13	5.48e-01	-9.62e-02	7.71e-01
Transcriptional Regulation by VENTX	38	5.49e-01	-5.62e-02	7.71e-01
Amine ligand-binding receptors	15	5.50e-01	-8.92e-02	7.72e-01
Xenobiotics	11	5.52e-01	1.04e-01	7.75e-01
TRP channels	17	5.54e-01	8.28e-02	7.77e-01
G alpha (s) signalling events	88	5.55e-01	-3.65e-02	7.77e-01
VxPx cargo-targeting to cilium	17	5.56e-01	8.25e-02	7.78e-01
Transcriptional regulation by small RNAs	57	5.57e-01	-4.50e-02	7.78e-01
Interleukin-37 signaling	20	5.60e-01	7.54e-02	7.80e-01
Synthesis of PE	12	5.60e-01	-9.72e-02	7.80e-01
Signaling by Interleukins	388	5.60e-01	1.73e-02	7.80e-01
STAT5 activation downstream of FLT3 ITD mutants	10	5.63e-01	-1.06e-01	7.83e-01
IRF3-mediated induction of type I IFN	12	5.63e-01	-9.63e-02	7.83e-01
Transport of the SLBP independent Mature mRNA	35	5.64e-01	-5.64e-02	7.83e-01
VEGFR2 mediated cell proliferation	19	5.64e-01	7.65e-02	7.83e-01
Synthesis of PC	25	5.66e-01	6.64e-02	7.84e-01
SUMOylation of SUMOylation proteins	35	5.68e-01	-5.58e-02	7.86e-01
Synthesis of bile acids and bile salts via 24-hydroxycholesterol	11	5.68e-01	-9.94e-02	7.86e-01
Biosynthesis of specialized proresolving mediators (SPMs)	14	5.69e-01	-8.78e-02	7.88e-01
Regulation of TP53 Degradation	35	5.71e-01	-5.54e-02	7.88e-01
NOTCH4 Intracellular Domain Regulates Transcription	19	5.71e-01	-7.51e-02	7.88e-01
Signaling by FGFR2 in disease	38	5.74e-01	-5.27e-02	7.91e-01
HSF1-dependent transactivation	33	5.74e-01	-5.65e-02	7.91e-01
RUNX2 regulates bone development	28	5.76e-01	-6.11e-02	7.92e-01
Cell-Cell communication	96	5.76e-01	-3.30e-02	7.92e-01
CLEC7A (Dectin-1) induces NFAT activation	11	5.76e-01	9.74e-02	7.92e-01
Metabolism of cofactors	19	5.79e-01	7.36e-02	7.94e-01
Negative regulation of FGFR4 signaling	27	5.81e-01	-6.14e-02	7.96e-01
RHOG GTPase cycle	72	5.81e-01	-3.76e-02	7.96e-01
Acyl chain remodelling of PS	16	5.83e-01	-7.93e-02	7.98e-01
Chromosome Maintenance	96	5.85e-01	-3.23e-02	7.99e-01
Phospholipase C-mediated cascade: FGFR1	11	5.85e-01	9.51e-02	7.99e-01
Separation of Sister Chromatids	159	5.86e-01	-2.50e-02	8.00e-01
Regulation of IFNA signaling	12	5.86e-01	9.07e-02	8.00e-01
Positive epigenetic regulation of rRNA expression	56	5.88e-01	-4.19e-02	8.01e-01
Miscellaneous transport and binding events	22	5.94e-01	6.57e-02	8.08e-01
Defensins	10	5.96e-01	9.67e-02	8.11e-01
RND3 GTPase cycle	37	5.97e-01	-5.02e-02	8.11e-01
Neurotransmitter release cycle	37	6.02e-01	4.96e-02	8.16e-01
Constitutive Signaling by AKT1 E17K in Cancer	26	6.03e-01	-5.90e-02	8.16e-01
B-WICH complex positively regulates rRNA expression	41	6.03e-01	4.69e-02	8.16e-01
Signaling by Receptor Tyrosine Kinases	472	6.03e-01	-1.40e-02	8.16e-01
Interactions of Vpr with host cellular proteins	37	6.04e-01	-4.93e-02	8.16e-01
Inhibition of DNA recombination at telomere	30	6.04e-01	-5.47e-02	8.16e-01
Recycling of bile acids and salts	10	6.08e-01	9.36e-02	8.21e-01
Pre-NOTCH Processing in Golgi	18	6.09e-01	-6.97e-02	8.21e-01
MyD88 cascade initiated on plasma membrane	83	6.10e-01	3.24e-02	8.21e-01
Toll Like Receptor 10 (TLR10) Cascade	83	6.10e-01	3.24e-02	8.21e-01
Toll Like Receptor 5 (TLR5) Cascade	83	6.10e-01	3.24e-02	8.21e-01
PLC beta mediated events	46	6.12e-01	4.33e-02	8.22e-01
Keratan sulfate biosynthesis	24	6.12e-01	-5.97e-02	8.22e-01
NOTCH2 intracellular domain regulates transcription	11	6.13e-01	-8.82e-02	8.22e-01
Ephrin signaling	19	6.16e-01	-6.65e-02	8.25e-01
Signaling by NTRKs	128	6.17e-01	2.56e-02	8.25e-01
Cytochrome P450 - arranged by substrate type	37	6.19e-01	-4.73e-02	8.27e-01
Nuclear signaling by ERBB4	29	6.20e-01	-5.32e-02	8.27e-01
Alpha-protein kinase 1 signaling pathway	11	6.20e-01	8.64e-02	8.27e-01
Activation of ATR in response to replication stress	33	6.21e-01	4.97e-02	8.28e-01
Negative regulation of FGFR1 signaling	28	6.25e-01	-5.34e-02	8.32e-01
CD209 (DC-SIGN) signaling	20	6.26e-01	6.30e-02	8.32e-01
Negative epigenetic regulation of rRNA expression	59	6.26e-01	-3.67e-02	8.32e-01
Cellular hexose transport	15	6.27e-01	-7.24e-02	8.33e-01
Aquaporin-mediated transport	38	6.29e-01	4.53e-02	8.35e-01
Heme signaling	44	6.31e-01	4.19e-02	8.35e-01
CASP8 activity is inhibited	11	6.31e-01	8.36e-02	8.35e-01
Dimerization of procaspase-8	11	6.31e-01	8.36e-02	8.35e-01
Regulation by c-FLIP	11	6.31e-01	8.36e-02	8.35e-01
Signaling by Insulin receptor	69	6.33e-01	-3.33e-02	8.36e-01
NRIF signals cell death from the nucleus	16	6.37e-01	-6.81e-02	8.41e-01
Mitotic Prophase	92	6.37e-01	2.84e-02	8.41e-01
InlB-mediated entry of Listeria monocytogenes into host cell	13	6.38e-01	-7.53e-02	8.41e-01
ISG15 antiviral mechanism	72	6.39e-01	3.20e-02	8.41e-01
Glucagon-type ligand receptors	23	6.41e-01	5.62e-02	8.43e-01
Synthesis of PA	31	6.43e-01	-4.81e-02	8.45e-01
TGF-beta receptor signaling activates SMADs	32	6.45e-01	-4.70e-02	8.47e-01
Regulation of TP53 Activity through Association with Co-factors	11	6.47e-01	-7.98e-02	8.48e-01
Negative regulation of MET activity	19	6.47e-01	6.07e-02	8.48e-01
Advanced glycosylation endproduct receptor signaling	13	6.48e-01	-7.32e-02	8.48e-01
AKT phosphorylates targets in the nucleus	10	6.48e-01	-8.34e-02	8.48e-01
NoRC negatively regulates rRNA expression	56	6.48e-01	-3.52e-02	8.48e-01
Early Phase of HIV Life Cycle	14	6.49e-01	7.02e-02	8.48e-01
Inflammasomes	21	6.51e-01	5.71e-02	8.49e-01
The canonical retinoid cycle in rods (twilight vision)	12	6.54e-01	-7.48e-02	8.52e-01
Blood group systems biosynthesis	16	6.55e-01	-6.45e-02	8.53e-01
AKT phosphorylates targets in the cytosol	14	6.57e-01	-6.86e-02	8.54e-01
CD28 co-stimulation	32	6.57e-01	-4.54e-02	8.54e-01
RUNX3 regulates p14-ARF	10	6.58e-01	8.09e-02	8.54e-01
Telomere C-strand synthesis initiation	13	6.59e-01	-7.08e-02	8.55e-01
Regulation of beta-cell development	20	6.60e-01	-5.68e-02	8.56e-01
EGFR downregulation	27	6.62e-01	4.86e-02	8.57e-01
TICAM1,TRAF6-dependent induction of TAK1 complex	11	6.63e-01	-7.60e-02	8.57e-01
Nuclear events stimulated by ALK signaling in cancer	18	6.63e-01	-5.93e-02	8.57e-01
COPI-independent Golgi-to-ER retrograde traffic	33	6.64e-01	-4.37e-02	8.57e-01
Integration of energy metabolism	91	6.65e-01	2.63e-02	8.57e-01
Protein-protein interactions at synapses	72	6.65e-01	2.95e-02	8.57e-01
RUNX2 regulates osteoblast differentiation	22	6.65e-01	-5.33e-02	8.57e-01
Pentose phosphate pathway	13	6.66e-01	-6.92e-02	8.57e-01
Erythropoietin activates RAS	13	6.69e-01	6.85e-02	8.61e-01
Transcription of E2F targets under negative control by DREAM complex	19	6.72e-01	5.61e-02	8.64e-01
Retrograde transport at the Trans-Golgi-Network	49	6.74e-01	-3.48e-02	8.65e-01
EPHB-mediated forward signaling	33	6.75e-01	-4.22e-02	8.65e-01
TICAM1, RIP1-mediated IKK complex recruitment	19	6.76e-01	5.54e-02	8.65e-01
Sensory perception of sweet, bitter, and umami (glutamate) taste	15	6.76e-01	6.24e-02	8.65e-01
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	11	6.76e-01	-7.27e-02	8.65e-01
APC/C:Cdc20 mediated degradation of Cyclin B	23	6.78e-01	-5.01e-02	8.66e-01
Diseases of signal transduction by growth factor receptors and second messengers	401	6.78e-01	-1.21e-02	8.66e-01
SUMO E3 ligases SUMOylate target proteins	162	6.81e-01	-1.87e-02	8.68e-01
RHOH GTPase cycle	35	6.82e-01	4.00e-02	8.68e-01
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	18	6.82e-01	-5.58e-02	8.68e-01
Metabolism of steroids	126	6.82e-01	-2.11e-02	8.68e-01
Collagen chain trimerization	38	6.83e-01	3.82e-02	8.68e-01
Transcriptional Regulation by TP53	346	6.84e-01	-1.28e-02	8.68e-01
RAC1 GTPase cycle	177	6.84e-01	1.77e-02	8.68e-01
Activation of BAD and translocation to mitochondria	14	6.85e-01	-6.27e-02	8.68e-01
Regulation of FOXO transcriptional activity by acetylation	10	6.85e-01	-7.40e-02	8.69e-01
Downregulation of ERBB2 signaling	27	6.88e-01	4.47e-02	8.71e-01
NOTCH3 Activation and Transmission of Signal to the Nucleus	25	6.89e-01	-4.63e-02	8.71e-01
SLC-mediated transmembrane transport	180	6.94e-01	1.70e-02	8.78e-01
Nicotinamide salvaging	16	6.96e-01	-5.64e-02	8.78e-01
activated TAK1 mediates p38 MAPK activation	19	6.97e-01	5.15e-02	8.78e-01
NEP/NS2 Interacts with the Cellular Export Machinery	32	6.97e-01	-3.97e-02	8.78e-01
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA	17	6.98e-01	-5.43e-02	8.78e-01
Downregulation of TGF-beta receptor signaling	26	6.99e-01	-4.38e-02	8.78e-01
NOTCH1 Intracellular Domain Regulates Transcription	47	6.99e-01	-3.26e-02	8.78e-01
Defects in vitamin and cofactor metabolism	21	6.99e-01	-4.87e-02	8.78e-01
Post-translational modification: synthesis of GPI-anchored proteins	63	7.00e-01	-2.81e-02	8.78e-01
Translocation of ZAP-70 to Immunological synapse	19	7.00e-01	5.11e-02	8.78e-01
Fertilization	11	7.02e-01	-6.67e-02	8.78e-01
Antimicrobial peptides	34	7.02e-01	-3.79e-02	8.78e-01
Downregulation of SMAD2/3:SMAD4 transcriptional activity	28	7.02e-01	-4.18e-02	8.78e-01
Signaling by ERBB2	47	7.04e-01	3.20e-02	8.81e-01
Triglyceride metabolism	28	7.06e-01	4.12e-02	8.81e-01
Lysine catabolism	12	7.07e-01	-6.26e-02	8.81e-01
Signaling by Non-Receptor Tyrosine Kinases	51	7.08e-01	3.03e-02	8.81e-01
Signaling by PTK6	51	7.08e-01	3.03e-02	8.81e-01
Activated NOTCH1 Transmits Signal to the Nucleus	31	7.08e-01	-3.88e-02	8.81e-01
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS)	10	7.09e-01	-6.81e-02	8.81e-01
Diseases of hemostasis	10	7.09e-01	-6.81e-02	8.81e-01
IGF1R signaling cascade	46	7.12e-01	3.14e-02	8.83e-01
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants	19	7.13e-01	4.88e-02	8.83e-01
Signaling by Ligand-Responsive EGFR Variants in Cancer	19	7.13e-01	4.88e-02	8.83e-01
Pyroptosis	25	7.13e-01	4.25e-02	8.83e-01
Interconversion of nucleotide di- and triphosphates	29	7.14e-01	3.93e-02	8.84e-01
IRS-related events triggered by IGF1R	45	7.15e-01	3.15e-02	8.84e-01
Transport of Ribonucleoproteins into the Host Nucleus	32	7.16e-01	-3.72e-02	8.84e-01
Glycogen metabolism	27	7.17e-01	4.03e-02	8.85e-01
Mitochondrial iron-sulfur cluster biogenesis	13	7.18e-01	-5.79e-02	8.85e-01
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	36	7.29e-01	-3.34e-02	8.98e-01
Activation of BH3-only proteins	28	7.31e-01	-3.76e-02	9.00e-01
G alpha (z) signalling events	37	7.32e-01	3.26e-02	9.00e-01
MAP kinase activation	63	7.35e-01	2.46e-02	9.02e-01
Pregnenolone biosynthesis	10	7.36e-01	-6.15e-02	9.02e-01
Homology Directed Repair	103	7.36e-01	-1.92e-02	9.02e-01
Caspase activation via Death Receptors in the presence of ligand	16	7.36e-01	4.86e-02	9.02e-01
Signal regulatory protein family interactions	11	7.38e-01	-5.82e-02	9.02e-01
Paradoxical activation of RAF signaling by kinase inactive BRAF	40	7.39e-01	-3.04e-02	9.02e-01
Signaling by RAS mutants	40	7.39e-01	-3.04e-02	9.02e-01
Signaling by moderate kinase activity BRAF mutants	40	7.39e-01	-3.04e-02	9.02e-01
Signaling downstream of RAS mutants	40	7.39e-01	-3.04e-02	9.02e-01
Plasma lipoprotein assembly	11	7.42e-01	-5.73e-02	9.05e-01
Metabolism of nitric oxide: NOS3 activation and regulation	15	7.43e-01	-4.90e-02	9.05e-01
Mitochondrial biogenesis	92	7.45e-01	1.96e-02	9.06e-01
RHOBTB2 GTPase cycle	23	7.46e-01	-3.91e-02	9.06e-01
Signaling by Leptin	11	7.46e-01	5.64e-02	9.06e-01
Endogenous sterols	22	7.46e-01	-3.98e-02	9.06e-01
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA	17	7.48e-01	4.50e-02	9.07e-01
SUMOylation of DNA damage response and repair proteins	77	7.48e-01	-2.12e-02	9.07e-01
Syndecan interactions	19	7.52e-01	-4.18e-02	9.11e-01
SUMOylation	168	7.53e-01	-1.41e-02	9.11e-01
Vasopressin regulates renal water homeostasis via Aquaporins	35	7.53e-01	3.07e-02	9.11e-01
FGFRL1 modulation of FGFR1 signaling	10	7.54e-01	5.73e-02	9.11e-01
PD-1 signaling	23	7.54e-01	-3.77e-02	9.11e-01
SUMOylation of ubiquitinylation proteins	39	7.55e-01	-2.89e-02	9.11e-01
Eicosanoid ligand-binding receptors	14	7.56e-01	4.79e-02	9.11e-01
Methylation	12	7.57e-01	-5.16e-02	9.11e-01
Aflatoxin activation and detoxification	12	7.57e-01	5.16e-02	9.11e-01
Aberrant regulation of mitotic exit in cancer due to RB1 defects	19	7.57e-01	4.10e-02	9.11e-01
TNFR1-induced proapoptotic signaling	13	7.59e-01	-4.92e-02	9.12e-01
Oncogene Induced Senescence	33	7.61e-01	3.06e-02	9.13e-01
Signaling by FLT3 ITD and TKD mutants	16	7.64e-01	4.33e-02	9.16e-01
Signaling by NTRK2 (TRKB)	25	7.65e-01	3.46e-02	9.16e-01
Export of Viral Ribonucleoproteins from Nucleus	33	7.65e-01	-3.00e-02	9.16e-01
ADORA2B mediated anti-inflammatory cytokines production	76	7.65e-01	1.98e-02	9.16e-01
RHOBTB1 GTPase cycle	23	7.67e-01	3.57e-02	9.16e-01
Regulation of HSF1-mediated heat shock response	79	7.67e-01	-1.93e-02	9.16e-01
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10	13	7.67e-01	-4.74e-02	9.16e-01
CTLA4 inhibitory signaling	19	7.71e-01	-3.86e-02	9.19e-01
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex	11	7.71e-01	5.06e-02	9.19e-01
Glucagon signaling in metabolic regulation	26	7.72e-01	-3.28e-02	9.19e-01
MET promotes cell motility	28	7.75e-01	3.12e-02	9.22e-01
Regulation of TP53 Expression and Degradation	36	7.77e-01	-2.72e-02	9.23e-01
Repression of WNT target genes	14	7.78e-01	-4.36e-02	9.23e-01
Postmitotic nuclear pore complex (NPC) reformation	27	7.78e-01	-3.13e-02	9.23e-01
NR1H2 and NR1H3-mediated signaling	41	7.80e-01	-2.52e-02	9.25e-01
Trafficking of GluR2-containing AMPA receptors	15	7.81e-01	-4.15e-02	9.25e-01
Inhibition of replication initiation of damaged DNA by RB1/E2F1	13	7.81e-01	4.45e-02	9.25e-01
Gene Silencing by RNA	83	7.84e-01	-1.74e-02	9.27e-01
Interleukin-12 family signaling	48	7.84e-01	-2.29e-02	9.27e-01
ROS and RNS production in phagocytes	33	7.86e-01	2.73e-02	9.28e-01
Activation of the pre-replicative complex	29	7.86e-01	2.91e-02	9.28e-01
RND1 GTPase cycle	37	7.87e-01	2.57e-02	9.28e-01
Cobalamin (Cbl, vitamin B12) transport and metabolism	15	7.89e-01	-3.99e-02	9.28e-01
RET signaling	36	7.90e-01	-2.57e-02	9.28e-01
BBSome-mediated cargo-targeting to cilium	21	7.90e-01	-3.36e-02	9.28e-01
Phospholipase C-mediated cascade; FGFR3	10	7.90e-01	4.86e-02	9.28e-01
Nonhomologous End-Joining (NHEJ)	37	7.91e-01	2.52e-02	9.28e-01
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression	26	7.91e-01	-3.00e-02	9.28e-01
TNFs bind their physiological receptors	22	7.92e-01	-3.26e-02	9.28e-01
Signaling by NOTCH1	73	7.92e-01	-1.78e-02	9.28e-01
Prolonged ERK activation events	14	7.94e-01	4.03e-02	9.30e-01
NCAM signaling for neurite out-growth	50	7.95e-01	2.12e-02	9.30e-01
Base-Excision Repair, AP Site Formation	25	7.99e-01	-2.94e-02	9.32e-01
TRAF6-mediated induction of TAK1 complex within TLR4 complex	16	8.00e-01	-3.66e-02	9.32e-01
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	12	8.00e-01	4.22e-02	9.32e-01
Synaptic adhesion-like molecules	19	8.02e-01	-3.33e-02	9.32e-01
Inactivation of APC/C via direct inhibition of the APC/C complex	19	8.02e-01	-3.32e-02	9.32e-01
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components	19	8.02e-01	-3.32e-02	9.32e-01
Cyclin D associated events in G1	47	8.03e-01	-2.11e-02	9.32e-01
G1 Phase	47	8.03e-01	-2.11e-02	9.32e-01
TP53 Regulates Metabolic Genes	84	8.03e-01	1.57e-02	9.32e-01
NS1 Mediated Effects on Host Pathways	40	8.04e-01	-2.27e-02	9.32e-01
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells	12	8.05e-01	-4.13e-02	9.32e-01
Thrombin signalling through proteinase activated receptors (PARs)	25	8.05e-01	2.86e-02	9.32e-01
Killing mechanisms	10	8.06e-01	-4.48e-02	9.33e-01
WNT5:FZD7-mediated leishmania damping	10	8.06e-01	-4.48e-02	9.33e-01
ATF4 activates genes in response to endoplasmic reticulum stress	26	8.08e-01	2.75e-02	9.34e-01
Biosynthesis of DHA-derived SPMs	12	8.12e-01	-3.98e-02	9.36e-01
Pyruvate metabolism and Citric Acid (TCA) cycle	51	8.12e-01	1.93e-02	9.36e-01
N-Glycan antennae elongation	13	8.12e-01	3.80e-02	9.36e-01
Signaling by BRAF and RAF1 fusions	59	8.13e-01	1.78e-02	9.36e-01
Beta-catenin phosphorylation cascade	17	8.15e-01	3.29e-02	9.37e-01
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	32	8.15e-01	-2.40e-02	9.37e-01
Serotonin Neurotransmitter Release Cycle	15	8.16e-01	-3.47e-02	9.38e-01
Glycogen synthesis	16	8.17e-01	3.35e-02	9.38e-01
Mitochondrial Fatty Acid Beta-Oxidation	35	8.18e-01	-2.24e-02	9.39e-01
Diseases of programmed cell death	51	8.19e-01	-1.85e-02	9.39e-01
Negative regulators of DDX58/IFIH1 signaling	35	8.21e-01	2.21e-02	9.40e-01
Netrin-1 signaling	42	8.21e-01	2.01e-02	9.40e-01
Insulin receptor signalling cascade	47	8.22e-01	-1.90e-02	9.40e-01
G-protein mediated events	50	8.22e-01	1.84e-02	9.40e-01
IKK complex recruitment mediated by RIP1	23	8.23e-01	2.69e-02	9.40e-01
Synthesis of bile acids and bile salts via 27-hydroxycholesterol	10	8.25e-01	-4.04e-02	9.41e-01
PI3K Cascade	38	8.28e-01	-2.04e-02	9.43e-01
MAPK1/MAPK3 signaling	253	8.28e-01	7.94e-03	9.43e-01
PKA activation	16	8.29e-01	-3.11e-02	9.44e-01
Caspase activation via extrinsic apoptotic signalling pathway	24	8.30e-01	2.53e-02	9.44e-01
Listeria monocytogenes entry into host cells	18	8.31e-01	-2.90e-02	9.45e-01
Signaling by TGFB family members	98	8.33e-01	1.23e-02	9.45e-01
Signaling by NOTCH2	32	8.33e-01	-2.15e-02	9.45e-01
TRAF3-dependent IRF activation pathway	14	8.34e-01	-3.24e-02	9.45e-01
Signalling to ERKs	33	8.34e-01	2.11e-02	9.45e-01
Apoptotic factor-mediated response	20	8.35e-01	2.70e-02	9.45e-01
RHO GTPases Activate Formins	111	8.35e-01	-1.15e-02	9.45e-01
SUMOylation of RNA binding proteins	47	8.36e-01	-1.75e-02	9.45e-01
Antigen Presentation: Folding, assembly and peptide loading of class I MHC	24	8.36e-01	2.44e-02	9.45e-01
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)	97	8.38e-01	-1.20e-02	9.45e-01
FGFR2 ligand binding and activation	14	8.39e-01	-3.15e-02	9.45e-01
Defects in cobalamin (B12) metabolism	13	8.39e-01	3.26e-02	9.45e-01
Stimuli-sensing channels	76	8.39e-01	1.35e-02	9.45e-01
IRAK1 recruits IKK complex	10	8.41e-01	3.66e-02	9.45e-01
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation	10	8.41e-01	3.66e-02	9.45e-01
Negative regulation of FLT3	15	8.42e-01	2.98e-02	9.45e-01
Nuclear Pore Complex (NPC) Disassembly	36	8.42e-01	-1.92e-02	9.45e-01
Nuclear Envelope Breakdown	53	8.42e-01	1.58e-02	9.45e-01
RHO GTPases activate PKNs	40	8.43e-01	-1.81e-02	9.45e-01
RNA Polymerase I Promoter Escape	41	8.44e-01	1.78e-02	9.45e-01
Purine salvage	13	8.46e-01	3.11e-02	9.46e-01
Adrenaline,noradrenaline inhibits insulin secretion	23	8.46e-01	2.34e-02	9.46e-01
Nucleotide catabolism	29	8.48e-01	-2.05e-02	9.47e-01
RHOQ GTPase cycle	58	8.48e-01	-1.45e-02	9.47e-01
Laminin interactions	23	8.49e-01	-2.30e-02	9.47e-01
Maturation of nucleoprotein	11	8.50e-01	-3.29e-02	9.48e-01
RUNX3 regulates NOTCH signaling	14	8.52e-01	2.88e-02	9.49e-01
IRS-mediated signalling	42	8.53e-01	1.65e-02	9.50e-01
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol	19	8.54e-01	-2.43e-02	9.50e-01
HDMs demethylate histones	22	8.55e-01	2.25e-02	9.50e-01
FLT3 Signaling	38	8.55e-01	-1.71e-02	9.50e-01
IL-6-type cytokine receptor ligand interactions	13	8.56e-01	2.91e-02	9.50e-01
Cell Cycle Checkpoints	239	8.57e-01	6.76e-03	9.50e-01
G-protein beta:gamma signalling	27	8.58e-01	-1.99e-02	9.50e-01
HDR through MMEJ (alt-NHEJ)	10	8.58e-01	3.27e-02	9.50e-01
Signalling to RAS	20	8.59e-01	-2.29e-02	9.50e-01
FOXO-mediated transcription	59	8.61e-01	1.32e-02	9.51e-01
Frs2-mediated activation	12	8.61e-01	2.91e-02	9.51e-01
Response of EIF2AK1 (HRI) to heme deficiency	15	8.62e-01	-2.59e-02	9.51e-01
Negative regulation of MAPK pathway	42	8.62e-01	1.55e-02	9.51e-01
G1/S-Specific Transcription	26	8.63e-01	1.96e-02	9.51e-01
SUMOylation of chromatin organization proteins	57	8.64e-01	-1.31e-02	9.52e-01
RHOBTB GTPase Cycle	35	8.65e-01	-1.67e-02	9.52e-01
CD28 dependent Vav1 pathway	11	8.66e-01	2.93e-02	9.53e-01
Deactivation of the beta-catenin transactivating complex	39	8.67e-01	-1.55e-02	9.53e-01
SLBP independent Processing of Histone Pre-mRNAs	10	8.69e-01	-3.02e-02	9.54e-01
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase	19	8.69e-01	-2.18e-02	9.54e-01
RNA Polymerase II Transcription	1221	8.72e-01	2.76e-03	9.56e-01
RAC3 GTPase cycle	88	8.72e-01	-9.90e-03	9.56e-01
Protein ubiquitination	67	8.74e-01	1.13e-02	9.56e-01
NOTCH2 Activation and Transmission of Signal to the Nucleus	22	8.74e-01	-1.95e-02	9.56e-01
Regulation of BACH1 activity	11	8.76e-01	-2.71e-02	9.58e-01
Signaling by MET	63	8.77e-01	-1.13e-02	9.58e-01
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux	34	8.78e-01	-1.53e-02	9.58e-01
Cyclin A/B1/B2 associated events during G2/M transition	23	8.81e-01	-1.80e-02	9.59e-01
Triglyceride catabolism	17	8.83e-01	-2.06e-02	9.59e-01
GPVI-mediated activation cascade	30	8.85e-01	-1.53e-02	9.59e-01
Acetylcholine Neurotransmitter Release Cycle	12	8.85e-01	-2.40e-02	9.59e-01
Signaling by NOTCH3	46	8.86e-01	1.22e-02	9.59e-01
PKA-mediated phosphorylation of CREB	18	8.86e-01	1.95e-02	9.59e-01
Activated point mutants of FGFR2	12	8.87e-01	2.38e-02	9.59e-01
Ca-dependent events	34	8.88e-01	1.40e-02	9.59e-01
Formation of the cornified envelope	23	8.88e-01	1.69e-02	9.59e-01
RAB geranylgeranylation	61	8.89e-01	-1.03e-02	9.59e-01
Activation of GABAB receptors	31	8.90e-01	1.44e-02	9.59e-01
GABA B receptor activation	31	8.90e-01	1.44e-02	9.59e-01
Gene expression (Transcription)	1353	8.90e-01	-2.24e-03	9.59e-01
Formation of Fibrin Clot (Clotting Cascade)	23	8.91e-01	1.66e-02	9.59e-01
APC truncation mutants have impaired AXIN binding	14	8.91e-01	2.11e-02	9.59e-01
AXIN missense mutants destabilize the destruction complex	14	8.91e-01	2.11e-02	9.59e-01
Signaling by AMER1 mutants	14	8.91e-01	2.11e-02	9.59e-01
Signaling by APC mutants	14	8.91e-01	2.11e-02	9.59e-01
Signaling by AXIN mutants	14	8.91e-01	2.11e-02	9.59e-01
Truncations of AMER1 destabilize the destruction complex	14	8.91e-01	2.11e-02	9.59e-01
RAC2 GTPase cycle	86	8.93e-01	-8.38e-03	9.60e-01
Diseases associated with the TLR signaling cascade	27	9.02e-01	1.37e-02	9.68e-01
Diseases of Immune System	27	9.02e-01	1.37e-02	9.68e-01
RORA activates gene expression	18	9.02e-01	1.67e-02	9.68e-01
TAK1 activates NFkB by phosphorylation and activation of IKKs complex	28	9.04e-01	1.31e-02	9.68e-01
Metal ion SLC transporters	21	9.05e-01	-1.50e-02	9.68e-01
GABA synthesis, release, reuptake and degradation	12	9.05e-01	1.98e-02	9.68e-01
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	15	9.06e-01	-1.77e-02	9.68e-01
DDX58/IFIH1-mediated induction of interferon-alpha/beta	68	9.06e-01	8.24e-03	9.68e-01
Cargo trafficking to the periciliary membrane	45	9.07e-01	1.00e-02	9.69e-01
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	47	9.10e-01	9.54e-03	9.71e-01
Cleavage of the damaged pyrimidine	23	9.13e-01	1.31e-02	9.72e-01
Depyrimidination	23	9.13e-01	1.31e-02	9.72e-01
Recognition and association of DNA glycosylase with site containing an affected pyrimidine	23	9.13e-01	1.31e-02	9.72e-01
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer	46	9.15e-01	9.13e-03	9.72e-01
Vpr-mediated nuclear import of PICs	34	9.15e-01	-1.06e-02	9.72e-01
Regulation of TP53 Activity	152	9.21e-01	-4.66e-03	9.78e-01
Phospholipid metabolism	187	9.25e-01	4.02e-03	9.80e-01
Vitamin B5 (pantothenate) metabolism	17	9.25e-01	1.32e-02	9.80e-01
Dopamine Neurotransmitter Release Cycle	20	9.29e-01	-1.15e-02	9.80e-01
E3 ubiquitin ligases ubiquitinate target proteins	48	9.29e-01	-7.41e-03	9.80e-01
Signaling by FGFR in disease	58	9.30e-01	-6.71e-03	9.80e-01
Phosphorylation of the APC/C	19	9.31e-01	-1.15e-02	9.80e-01
S33 mutants of beta-catenin aren’t phosphorylated	15	9.31e-01	1.30e-02	9.80e-01
S37 mutants of beta-catenin aren’t phosphorylated	15	9.31e-01	1.30e-02	9.80e-01
S45 mutants of beta-catenin aren’t phosphorylated	15	9.31e-01	1.30e-02	9.80e-01
Signaling by CTNNB1 phospho-site mutants	15	9.31e-01	1.30e-02	9.80e-01
Signaling by GSK3beta mutants	15	9.31e-01	1.30e-02	9.80e-01
T41 mutants of beta-catenin aren’t phosphorylated	15	9.31e-01	1.30e-02	9.80e-01
Activation of RAC1	12	9.34e-01	1.38e-02	9.80e-01
SUMOylation of DNA methylation proteins	16	9.34e-01	-1.19e-02	9.80e-01
PERK regulates gene expression	31	9.35e-01	8.47e-03	9.80e-01
Polo-like kinase mediated events	15	9.35e-01	-1.21e-02	9.80e-01
Class I peroxisomal membrane protein import	20	9.35e-01	-1.05e-02	9.80e-01
Cell junction organization	67	9.36e-01	-5.69e-03	9.80e-01
RAF/MAP kinase cascade	247	9.36e-01	-2.97e-03	9.80e-01
DAG and IP3 signaling	38	9.38e-01	7.34e-03	9.80e-01
Metabolism of steroid hormones	23	9.39e-01	-9.28e-03	9.80e-01
PECAM1 interactions	12	9.40e-01	-1.26e-02	9.80e-01
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants	57	9.41e-01	-5.65e-03	9.80e-01
Constitutive Signaling by NOTCH1 PEST Domain Mutants	57	9.41e-01	-5.65e-03	9.80e-01
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer	57	9.41e-01	-5.65e-03	9.80e-01
Signaling by NOTCH1 PEST Domain Mutants in Cancer	57	9.41e-01	-5.65e-03	9.80e-01
Signaling by NOTCH1 in Cancer	57	9.41e-01	-5.65e-03	9.80e-01
Circadian Clock	68	9.41e-01	-5.15e-03	9.80e-01
TRAF6 mediated IRF7 activation	16	9.43e-01	1.03e-02	9.81e-01
Sensory perception of taste	19	9.45e-01	-9.22e-03	9.81e-01
Processing and activation of SUMO	10	9.46e-01	-1.24e-02	9.81e-01
p38MAPK events	13	9.46e-01	-1.08e-02	9.81e-01
IRAK2 mediated activation of TAK1 complex	10	9.46e-01	-1.23e-02	9.81e-01
Sialic acid metabolism	27	9.46e-01	-7.49e-03	9.81e-01
Incretin synthesis, secretion, and inactivation	12	9.51e-01	-1.03e-02	9.84e-01
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	12	9.51e-01	-1.03e-02	9.84e-01
Metalloprotease DUBs	20	9.53e-01	7.56e-03	9.86e-01
TRAF6 mediated NF-kB activation	25	9.55e-01	6.46e-03	9.87e-01
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1	18	9.58e-01	-7.17e-03	9.87e-01
Signaling by TGF-beta Receptor Complex	74	9.58e-01	-3.54e-03	9.87e-01
HDR through Homologous Recombination (HRR)	65	9.59e-01	-3.72e-03	9.87e-01
Erythrocytes take up carbon dioxide and release oxygen	12	9.59e-01	-8.62e-03	9.87e-01
O2/CO2 exchange in erythrocytes	12	9.59e-01	-8.62e-03	9.87e-01
Activated NTRK2 signals through FRS2 and FRS3	11	9.59e-01	-8.87e-03	9.87e-01
MET activates PTK2 signaling	18	9.60e-01	6.89e-03	9.87e-01
Signaling by RAF1 mutants	36	9.62e-01	4.58e-03	9.88e-01
ERK/MAPK targets	22	9.63e-01	-5.78e-03	9.88e-01
Sphingolipid de novo biosynthesis	40	9.64e-01	-4.17e-03	9.89e-01
Signaling by FGFR4	37	9.64e-01	-4.23e-03	9.89e-01
Interleukin-17 signaling	67	9.67e-01	-2.93e-03	9.91e-01
Signaling by FGFR3	37	9.68e-01	3.80e-03	9.91e-01
NOTCH4 Activation and Transmission of Signal to the Nucleus	11	9.68e-01	6.96e-03	9.91e-01
Growth hormone receptor signaling	19	9.73e-01	4.42e-03	9.95e-01
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest	16	9.73e-01	4.82e-03	9.95e-01
RHO GTPases activate IQGAPs	11	9.75e-01	5.52e-03	9.95e-01
G beta:gamma signalling through PI3Kgamma	20	9.76e-01	-3.85e-03	9.96e-01
Phospholipase C-mediated cascade; FGFR2	13	9.78e-01	-4.39e-03	9.96e-01
Carnitine metabolism	12	9.80e-01	4.27e-03	9.96e-01
RHOJ GTPase cycle	53	9.80e-01	-2.01e-03	9.96e-01
MASTL Facilitates Mitotic Progression	10	9.81e-01	4.38e-03	9.96e-01
CaM pathway	32	9.81e-01	-2.37e-03	9.96e-01
Calmodulin induced events	32	9.81e-01	-2.37e-03	9.96e-01
Activation of HOX genes during differentiation	69	9.83e-01	1.48e-03	9.96e-01
Activation of anterior HOX genes in hindbrain development during early embryogenesis	69	9.83e-01	1.48e-03	9.96e-01
Intrinsic Pathway of Fibrin Clot Formation	13	9.84e-01	3.21e-03	9.96e-01
Neurexins and neuroligins	47	9.84e-01	-1.68e-03	9.96e-01
Interleukin-20 family signaling	16	9.84e-01	2.86e-03	9.96e-01
Intrinsic Pathway for Apoptosis	53	9.85e-01	1.51e-03	9.96e-01
Lysosphingolipid and LPA receptors	10	9.87e-01	-3.08e-03	9.97e-01
Signaling by NTRK3 (TRKC)	17	9.87e-01	-2.22e-03	9.97e-01
FLT3 signaling in disease	28	9.87e-01	1.72e-03	9.97e-01
Citric acid cycle (TCA cycle)	22	9.88e-01	1.83e-03	9.97e-01
Signaling by WNT in cancer	30	9.90e-01	-1.31e-03	9.98e-01
Common Pathway of Fibrin Clot Formation	13	9.90e-01	-1.95e-03	9.98e-01
Gluconeogenesis	29	9.91e-01	1.16e-03	9.98e-01
The NLRP3 inflammasome	16	9.92e-01	-1.52e-03	9.98e-01
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation	10	9.93e-01	-1.52e-03	9.99e-01
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	15	9.95e-01	9.43e-04	1.00e+00
Epigenetic regulation of gene expression	97	9.97e-01	-2.32e-04	1.00e+00
Signaling by FGFR1	45	9.98e-01	2.66e-04	1.00e+00
mRNA decay by 5’ to 3’ exoribonuclease	15	9.99e-01	2.42e-04	1.00e+00
Branched-chain amino acid catabolism	21	1.00e+00	-7.51e-06	1.00e+00
Cleavage of the damaged purine	18	1.00e+00	-5.84e-06	1.00e+00
Depurination	18	1.00e+00	-5.84e-06	1.00e+00
Recognition and association of DNA glycosylase with site containing an affected purine	18	1.00e+00	-5.84e-06	1.00e+00

---

Detailed Gene set reports

Classical antibody-mediated complement activation

Classical antibody-mediated complement activation

	199
set	Classical antibody-mediated complement activation
setSize	53
pANOVA	1.27e-20
s.dist	-0.739
p.adjustANOVA	1.22e-17

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
IGHG2	-9010

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
IGHG2	-9010
IGHV3-30	-8906
IGHG3	-8775
IGLV1-47	-8713
C1R	-8672
IGLV3-21	-8651
IGKV3-15	-8522
IGHG4	-8417
IGKV3-20	-8400
C1QC	-8135
IGLV2-23	-8106
IGLV3-19	-7984
IGHV4-59	-7466
IGKV2-30	-7018
IGKV4-1	-6785
C1S	-6748
C1QB	-6698
IGLV6-57	-6578
IGLV1-40	-5992
IGHV4-39	-5760
IGKV2D-28	-5697
IGHV1-2	-5528
IGHG1	-5275
IGLV1-51	-5257
IGKC	-5210
IGKV1D-39	-4621
IGKV1-12	-4498
C1QA	-3836
IGHV4-34	-3644
IGLV1-44	-1280
IGHV3-48	-616
IGKV1-16	-593
IGHV3-23	658
IGKV1-33	3826

---

Initial triggering of complement

Initial triggering of complement

	562
set	Initial triggering of complement
setSize	66
pANOVA	1.89e-20
s.dist	-0.659
p.adjustANOVA	1.22e-17

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
CFD	-9361
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
CFD	-9361
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
IGHG2	-9010
IGHV3-30	-8906
C2	-8903
MASP1	-8868
IGHG3	-8775
IGLV1-47	-8713
C1R	-8672
IGLV3-21	-8651
IGKV3-15	-8522
IGHG4	-8417
IGKV3-20	-8400
C1QC	-8135
IGLV2-23	-8106
IGLV3-19	-7984
IGHV4-59	-7466
CFB	-7163
C4A	-7114
IGKV2-30	-7018
IGKV4-1	-6785
C1S	-6748
C1QB	-6698
IGLV6-57	-6578
C4B	-6148
FCN2	-6048
C3	-5996
IGLV1-40	-5992
IGHV4-39	-5760
IGKV2D-28	-5697
IGHV1-2	-5528
IGHG1	-5275
IGLV1-51	-5257
IGKC	-5210
IGKV1D-39	-4621
IGKV1-12	-4498
C1QA	-3836
IGHV4-34	-3644
MASP2	-2462
IGLV1-44	-1280
IGHV3-48	-616
IGKV1-16	-593
COLEC11	-442
IGHV3-23	658
IGKV1-33	3826
GZMM	4366
FCN1	7408
FCN3	9028

---

Metabolism of RNA

Metabolism of RNA

	670
set	Metabolism of RNA
setSize	679
pANOVA	2.52e-20
s.dist	-0.208
p.adjustANOVA	1.22e-17

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PWP2	-9356
NOP2	-9329
GTF2F1	-9321
APOBEC3C	-9198
NOL12	-9160
RPS4X	-9157
TRMT61A	-9138
TNKS1BP1	-9132
MT-TA	-9130
SNRPA	-9083
PES1	-9076
WDR46	-9022
AAAS	-9006
DHX37	-8992
MT-TN	-8947
UTP3	-8901
MT-TC	-8892
TRMT1	-8875
MT-TY	-8859
DHX38	-8848

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PWP2	-9356
NOP2	-9329
GTF2F1	-9321
APOBEC3C	-9198
NOL12	-9160
RPS4X	-9157
TRMT61A	-9138
TNKS1BP1	-9132
MT-TA	-9130
SNRPA	-9083
PES1	-9076
WDR46	-9022
AAAS	-9006
DHX37	-8992
MT-TN	-8947
UTP3	-8901
MT-TC	-8892
TRMT1	-8875
MT-TY	-8859
DHX38	-8848
SF3A2	-8838
PRPF31	-8819
CASC3	-8770
FTSJ3	-8731
RPLP2	-8715
RRP9	-8711
CTNNBL1	-8707
METTL1	-8677
RPP25	-8676
NOB1	-8667
SART1	-8657
EXOSC7	-8626
SYMPK	-8569
RPL3	-8564
MT-TS1	-8492
NOL6	-8490
SRSF9	-8488
RPP38	-8462
SEC13	-8457
GEMIN8	-8409
RPL23	-8406
U2AF2	-8365
QTRT1	-8311
RPS14	-8278
PQBP1	-8268
DDX49	-8262
RPS12	-8256
NXF1	-8248
TNFSF13	-8183
PUS1	-8174
RPL36	-8166
RPL19	-8133
ENPP2	-8131
RPS28	-8128
SRRT	-8099
HNRNPUL1	-8091
SF3A3	-8087
RPL28	-8031
SNRPD2	-7961
RRP1	-7943
RPL37	-7930
RPP21	-7916
SF3B2	-7914
RPS26	-7908
XAB2	-7906
FTSJ1	-7855
EDC4	-7845
RPL31	-7842
DDX23	-7814
PABPC1	-7807
LAS1L	-7790
WDR18	-7755
PCBP2	-7750
PRPF19	-7727
PRPF6	-7705
RPL26L1	-7694
NUP188	-7684
DDX42	-7682
GEMIN4	-7657
POLR2G	-7651
UBA52	-7643
RPS5	-7633
PSMA7	-7617
RTCB	-7593
DDX39A	-7582
PSMB7	-7580
POP1	-7576
SRRM2	-7563
PSMC3	-7538
EBNA1BP2	-7528
DHX16	-7513
SUPT5H	-7505
CSNK1E	-7502
SMG9	-7490
RPL13	-7472
RPS18	-7468
GPKOW	-7457
POLR2F	-7453
RPL7A	-7394
RPS16	-7390
NCL	-7363
RPS10	-7354
NUP85	-7351
RPL26	-7340
DNAJC8	-7314
HSD17B10	-7304
RPL10A	-7253
RPL30	-7217
TBL3	-7214
ACTB	-7187
BMS1	-7180
RPS11	-7138
PSMD4	-7134
RPL4	-7127
POLDIP3	-7123
LSM7	-7099
CNOT3	-7096
SF3B5	-7088
FAU	-7067
PTBP1	-7053
RPL13A	-7019
AKT1	-6976
POLR2H	-6957
NAT10	-6956
PSMC5	-6942
NOP14	-6926
KHSRP	-6920
RPS17	-6903
TXNL4A	-6897
MT-TE	-6890
GTF2H4	-6879
URM1	-6847
U2AF1L4	-6824
EXOSC2	-6796
RPS15	-6758
RPL29	-6731
PRKCD	-6726
TRMT112	-6708
PSMD8	-6703
RPL36AL	-6668
MTERF4	-6607
DUS2	-6565
UTP14A	-6554
RPS20	-6537
POP5	-6505
RPL38	-6495
RPL12	-6483
ALYREF	-6482
HNRNPF	-6479
PPP2R1A	-6433
POP4	-6430
CSNK1D	-6427
PSMB4	-6417
RPLP0	-6397
GTPBP3	-6389
ZRSR2	-6384
CTU1	-6379
FBL	-6366
RPL10	-6333
RPL8	-6300
DKC1	-6279
POM121	-6225
RPL5	-6221
EXOSC1	-6182
CPSF1	-6174
RPL37A	-6135
WBP11	-6121
RPL27A	-6113
RRP36	-6103
GEMIN7	-6084
PRMT5	-6058
CPSF3	-5988
SMG6	-5978
RPS2	-5959
RPS8	-5958
ISY1	-5957
CSTF2	-5928
NOC4L	-5927
HNRNPA0	-5913
SNRNP200	-5911
PRPF8	-5909
DCPS	-5906
RPS21	-5899
RPL11	-5867
RPS27	-5866
RPLP1	-5846
RPS6	-5819
UTP4	-5802
PSMD9	-5765
RPL17	-5749
EIF4B	-5716
PUF60	-5710
PPIE	-5709
RPL15	-5698
CD44	-5695
EXOSC10	-5673
GEMIN5	-5672
RPL32	-5598
YBX1	-5558
PSMF1	-5494
IMP4	-5469
SF3B4	-5464
RPL41	-5397
BOP1	-5385
NT5C3B	-5378
THOC6	-5375
RPL18	-5360
EXOSC4	-5333
PSMB3	-5327
IMP3	-5301
PABPN1	-5294
RCL1	-5265
MAGOH	-5252
RPL23A	-5246
NHP2	-5244
RNMT	-5242
PSMD3	-5235
CLP1	-5224
TFIP11	-5209
PSMB1	-5182
RPL34	-5148
CSTF2T	-5145
PSMD7	-5070
RPL7	-5057
RPL18A	-5015
WDR77	-5011
EDC3	-5005
PELP1	-5004
CNOT10	-4978
LAGE3	-4959
SUGP1	-4955
PSMD14	-4951
PSMB10	-4948
RPL6	-4942
RPS23	-4940
MRM1	-4933
CHTOP	-4899
RAN	-4882
PSMC2	-4880
EFTUD2	-4866
PSMB6	-4849
RPS19	-4848
RPS3	-4842
CLNS1A	-4821
POLR2I	-4811
THOC5	-4803
POLR2C	-4802
SLBP	-4786
NOP56	-4726
GLE1	-4716
PSMD2	-4715
SF3B3	-4713
CHERP	-4694
THOC3	-4640
NUP62	-4588
PSMA1	-4587
SNU13	-4584
PARN	-4578
ERCC3	-4568
RPL14	-4555
SF3A1	-4535
TPR	-4504
CNOT1	-4501
SNRPF	-4412
CPSF7	-4400
POLR2E	-4389
HNRNPM	-4367
PSMA5	-4364
PSMD10	-4338
SMG8	-4290
PSMD1	-4278
RBM5	-4257
TRMU	-4256
NOP10	-4184
NUP214	-4176
RPS15A	-4165
POP7	-4150
SNUPN	-4143
PRPF4	-4133
SNRPC	-4078
SKIV2L	-4037
CTU2	-4024
HSPA8	-3981
FIP1L1	-3969
SF1	-3967
EMG1	-3956
HNRNPL	-3942
DCP1B	-3939
RPL27	-3935
WDR33	-3894
OSGEP	-3892
RNPS1	-3887
PHF5A	-3866
WDR61	-3852
NXT1	-3849
SNRNP70	-3831
RAE1	-3807
RPL35	-3792
PATL1	-3789
SNRPB	-3786
ZNF473	-3775
HNRNPA1	-3707
MRM2	-3702
RPL39L	-3699
NUP88	-3689
POM121C	-3677
GSPT2	-3673
RTRAF	-3664
SNRNP35	-3639
THG1L	-3634
DDX1	-3630
UPF3A	-3628
DDX39B	-3594
RPL39	-3539
SNRNP40	-3511
PSMC4	-3510
PCBP1	-3508
CSTF1	-3499
ADAT3	-3460
NUP98	-3400
POLR2J	-3355
FUS	-3329
EIF4A1	-3326
CPSF4	-3300
USP39	-3277
LSM4	-3268
RPS9	-3253
SMG5	-3218
UTP25	-3217
PSMB2	-3187
CD2BP2	-3185
EXOSC5	-3179
NUP93	-3163
BYSL	-3140
RPS24	-3138
UPF1	-3106
RPS29	-3082
DHX9	-3009
TYW1	-3002
EIF4G1	-2994
CWC15	-2981
NUP43	-2946
WDR4	-2932
CNOT8	-2920
BUD31	-2917
METTL3	-2854
MRM3	-2812
UBB	-2810
SNRNP25	-2769
THADA	-2743
PDCD11	-2693
TSR3	-2647
UBC	-2608
SF3B6	-2592
PSMD6	-2563
ELAC2	-2557
PPIH	-2545
EXOSC3	-2536
PSMB5	-2492
ERCC2	-2482
LSM10	-2464
PSMD13	-2447
WDR12	-2378
POLR2L	-2358
UTP18	-2303
GEMIN6	-2291
SRSF4	-2198
HNRNPD	-2083
RPS27A	-2058
GTF2F2	-2047
PHAX	-2027
TSR1	-2001
CDC5L	-1948
TRMT5	-1934
ELAVL1	-1918
ADARB1	-1868
RPP40	-1863
PAN2	-1850
EXOSC6	-1847
RPL35A	-1829
MNAT1	-1809
SRSF2	-1800
IGF2BP2	-1772
RRP7A	-1767
RBM28	-1756
CNOT2	-1742
SNRPD3	-1710
SNW1	-1709
NIP7	-1693
PSME3	-1691
PLRG1	-1620
PDCD7	-1613
PRCC	-1608
XRN2	-1560
MAPKAPK2	-1543
TRMT12	-1541
POLR2D	-1531
ANP32A	-1505
SENP3	-1401
QTRT2	-1383
GNL3	-1329
LTV1	-1318
PSMC1	-1275
POLR2A	-1215
RPS4Y1	-1198
RBMX	-1191
PRORP	-1052
ZBTB8OS	-1020
LSM1	-961
TSEN34	-951
HNRNPR	-923
RIOK2	-891
NSUN4	-779
UTP14C	-777
PPP2CA	-765
SEM1	-739
HSPB1	-690
NSUN2	-681
H19	-661
PSME1	-634
PRPF3	-565
RBM8A	-558
PSMA2	-550
RPS25	-545
EPRS1	-493
DCAF13	-448
RPL21	-383
POLR2B	-362
PSMD11	-353
PSMB8	-350
RPS3A	-334
SARNP	-320
SLU7	-312
RPS13	-295
ZMAT5	-291
EIF4A3	-261
GTF2H2	-233
CNOT4	-181
RPSA	-148
LSM2	-119
HNRNPH2	-106
NOL11	-105
DIMT1	-58
NUP155	-51
UTP20	94
WDR43	176
PAIP1	229
NUP42	299
CWC25	348
ISG20L2	384
SNRPB2	407
YWHAB	461
PRPF38A	501
RBM17	555
HNRNPK	570
SF3B1	605
PSME4	609
TSEN54	622
SNRPE	636
MT-ND4L	673
DDX47	693
IGF2	699
RBM22	748
LCMT2	753
SRSF6	762
NUP205	808
PPIL1	835
PNO1	843
ZC3H11A	877
WDR3	916
SMG7	1071
TSEN2	1085
RPS7	1197
ETF1	1218
RPS27L	1251
SRSF1	1269
RPL22	1273
HNRNPA3	1275
RPL24	1297
TTC37	1345
NUP210	1376
LSM6	1400
RIOK1	1448
TRMT44	1493
U2AF1	1501
APOBEC2	1502
TYW3	1505
MAPK11	1544
NUP153	1582
NCBP2	1609
PSMA6	1616
NUP160	1654
ADAR	1656
NOL9	1697
PSMA3	1706
SNRNP27	1733
MTO1	1735
CRNKL1	1786
UPF3B	1800
SNRPD1	1811
PPP2R2A	1826
PSMC6	1856
HNRNPU	1894
UPF2	1902
TRMT6	1904
SNRPN	1947
EXOSC9	1963
HNRNPC	2019
CDK7	2033
GSPT1	2097
CWC27	2100
PUS7	2110
SMN1	2245
WTAP	2257
TRIT1	2284
NUP54	2334
TGS1	2340
DHX15	2344
UTP6	2380
MAPK14	2383
MT-ATP8	2391
THOC1	2410
GTF2H1	2425
FAM98B	2499
DIS3	2583
FCF1	2588
WBP4	2599
HSPA1A	2615
NUP35	2637
EXOSC8	2653
HBS1L	2680
YWHAZ	2683
RPP14	2689
DDX46	2690
RPPH1	2704
CNOT11	2708
PPWD1	2719
C2orf49	2723
DDX20	2742
GPRC5A	2817
GTF2H5	2842
HEATR1	2886
PPIL4	3078
PSMD5	3165
MTREX	3201
XPOT	3208
CCNH	3223
SRRM1	3239
GEMIN2	3260
POLR2K	3276
PSME2	3291
NCBP1	3300
ERI1	3312
TRA2B	3359
DCP1A	3372
SET	3408
SNRPG	3445
TRMT10A	3463
CDC40	3497
HNRNPA2B1	3590
DDX6	3662
SRSF10	3717
LSM3	3732
ZCRB1	3737
CSTF3	3743
RPL3L	3763
LSM11	3789
RPP30	3814
SYF2	3823
FYTTD1	3832
TRNT1	3848
MT-ATP6	3857
TRMT10C	3872
HNRNPH1	3884
METTL14	3902
AQR	3920
PAPOLA	3988
BCAS2	4006
GTF2H3	4041
ALKBH8	4069
PSMA4	4076
PNRC2	4126
NOP58	4137
ADAT2	4146
GAR1	4148
TEX10	4243
PSMB9	4260
TRMT11	4271
SRSF11	4277
MT-CO1	4282
MT-CO2	4296
CPSF2	4410
EIF4A2	4494
TSEN15	4503
CCAR1	4515
PSMD12	4558
MPHOSPH6	4600
PPIL6	4605
SRSF5	4637
NDC1	4688
NUP133	4739
SNRPA1	4781
PRKCA	4793
PUS3	4816
WDR75	4848
THOC2	4878
SMNDC1	4899
NUP107	4939
RNGTT	4943
MT-ND5	5007
ADAT1	5010
LSM5	5056
MT-CYB	5065
RANBP2	5097
U2SURP	5105
TPRKB	5260
TRDMT1	5287
CDKAL1	5415
EIF4E	5439
SNRNP48	5507
CWC22	5545
CNOT6	5548
TRMT9B	5622
CNOT7	5637
TRMT61B	5708
UTP11	5716
NUP37	5735
MT-ND6	5763
RNPC3	5847
NUP50	5855
TP53RK	5880
WDR36	5894
THOC7	5904
THUMPD1	5914
LSM8	5915
RIOK3	6036
SEH1L	6077
KRR1	6130
PPIL3	6145
NSUN6	6287
PCF11	6323
MPHOSPH10	6348
RPL9	6370
TFB1M	6373
DDX21	6458
NUDT21	6472
DDX5	6525
MAGOHB	6565
RPL22L1	6595
UTP15	6799
PRPF40A	6846
RPL36A	6879
SRSF7	6903
TYW5	6915
MT-ND4	6917
SMG1	6931
DDX52	6981
XRN1	7010
DCP2	7085
SRSF3	7163
XPO1	7330
MT-ND2	7484
PAN3	7533
TRMT13	7616
MT-ND1	7626
MT-RNR1	7788
GCFC2	7953
TNPO1	7962
MT-CO3	8009
C1D	8221
ZFP36L1	8267
MT-TP	8315
MT-ND3	8619
CNOT6L	8749
NUP58	8794
APOBEC3A	8866
MYC	9159
MT-RNR2	9249
ZFP36	9390

---

rRNA processing in the nucleus and cytosol

rRNA processing in the nucleus and cytosol

	1448
set	rRNA processing in the nucleus and cytosol
setSize	190
pANOVA	5.35e-19
s.dist	-0.374
p.adjustANOVA	1.95e-16

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PWP2	-9356
NOP2	-9329
NOL12	-9160
RPS4X	-9157
PES1	-9076
WDR46	-9022
DHX37	-8992
UTP3	-8901
FTSJ3	-8731
RPLP2	-8715
RRP9	-8711
RPP25	-8676
NOB1	-8667
EXOSC7	-8626
RPL3	-8564
NOL6	-8490
RPP38	-8462
RPL23	-8406
RPS14	-8278
DDX49	-8262

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PWP2	-9356
NOP2	-9329
NOL12	-9160
RPS4X	-9157
PES1	-9076
WDR46	-9022
DHX37	-8992
UTP3	-8901
FTSJ3	-8731
RPLP2	-8715
RRP9	-8711
RPP25	-8676
NOB1	-8667
EXOSC7	-8626
RPL3	-8564
NOL6	-8490
RPP38	-8462
RPL23	-8406
RPS14	-8278
DDX49	-8262
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RRP1	-7943
RPL37	-7930
RPP21	-7916
RPS26	-7908
RPL31	-7842
LAS1L	-7790
WDR18	-7755
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
EBNA1BP2	-7528
CSNK1E	-7502
RPL13	-7472
RPS18	-7468
RPL7A	-7394
RPS16	-7390
NCL	-7363
RPS10	-7354
RPL26	-7340
RPL10A	-7253
RPL30	-7217
TBL3	-7214
BMS1	-7180
RPS11	-7138
RPL4	-7127
FAU	-7067
RPL13A	-7019
NAT10	-6956
NOP14	-6926
RPS17	-6903
EXOSC2	-6796
RPS15	-6758
RPL29	-6731
TRMT112	-6708
RPL36AL	-6668
UTP14A	-6554
RPS20	-6537
RPL38	-6495
RPL12	-6483
CSNK1D	-6427
RPLP0	-6397
FBL	-6366
RPL10	-6333
RPL8	-6300
DKC1	-6279
RPL5	-6221
EXOSC1	-6182
RPL37A	-6135
RPL27A	-6113
RRP36	-6103
RPS2	-5959
RPS8	-5958
NOC4L	-5927
RPS21	-5899
RPL11	-5867
RPS27	-5866
RPLP1	-5846
RPS6	-5819
UTP4	-5802
RPL17	-5749
RPL15	-5698
EXOSC10	-5673
RPL32	-5598
IMP4	-5469
RPL41	-5397
BOP1	-5385
RPL18	-5360
EXOSC4	-5333
IMP3	-5301
RCL1	-5265
RPL23A	-5246
NHP2	-5244
RPL34	-5148
RPL7	-5057
RPL18A	-5015
PELP1	-5004
RPL6	-4942
RPS23	-4940
RPS19	-4848
RPS3	-4842
NOP56	-4726
SNU13	-4584
RPL14	-4555
NOP10	-4184
RPS15A	-4165
EMG1	-3956
RPL27	-3935
RPL35	-3792
RPL39L	-3699
RPL39	-3539
RPS9	-3253
UTP25	-3217
EXOSC5	-3179
BYSL	-3140
RPS24	-3138
RPS29	-3082
PDCD11	-2693
TSR3	-2647
EXOSC3	-2536
WDR12	-2378
UTP18	-2303
RPS27A	-2058
TSR1	-2001
RPP40	-1863
EXOSC6	-1847
RPL35A	-1829
RRP7A	-1767
RBM28	-1756
NIP7	-1693
XRN2	-1560
SENP3	-1401
GNL3	-1329
LTV1	-1318
RPS4Y1	-1198
RIOK2	-891
UTP14C	-777
RPS25	-545
DCAF13	-448
RPL21	-383
RPS3A	-334
RPS13	-295
RPSA	-148
NOL11	-105
DIMT1	-58
UTP20	94
WDR43	176
ISG20L2	384
DDX47	693
PNO1	843
WDR3	916
RPS7	1197
RPS27L	1251
RPL22	1273
RPL24	1297
RIOK1	1448
NOL9	1697
EXOSC9	1963
UTP6	2380
DIS3	2583
FCF1	2588
EXOSC8	2653
RPP14	2689
HEATR1	2886
MTREX	3201
ERI1	3312
RPL3L	3763
RPP30	3814
NOP58	4137
GAR1	4148
TEX10	4243
MPHOSPH6	4600
WDR75	4848
UTP11	5716
WDR36	5894
THUMPD1	5914
RIOK3	6036
KRR1	6130
MPHOSPH10	6348
RPL9	6370
DDX21	6458
RPL22L1	6595
UTP15	6799
RPL36A	6879
DDX52	6981
C1D	8221

---

Creation of C4 and C2 activators

Creation of C4 and C2 activators

	227
set	Creation of C4 and C2 activators
setSize	59
pANOVA	8.7e-19
s.dist	-0.666
p.adjustANOVA	2.52e-16

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
IGHG2	-9010

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
IGHG2	-9010
IGHV3-30	-8906
MASP1	-8868
IGHG3	-8775
IGLV1-47	-8713
C1R	-8672
IGLV3-21	-8651
IGKV3-15	-8522
IGHG4	-8417
IGKV3-20	-8400
C1QC	-8135
IGLV2-23	-8106
IGLV3-19	-7984
IGHV4-59	-7466
IGKV2-30	-7018
IGKV4-1	-6785
C1S	-6748
C1QB	-6698
IGLV6-57	-6578
FCN2	-6048
IGLV1-40	-5992
IGHV4-39	-5760
IGKV2D-28	-5697
IGHV1-2	-5528
IGHG1	-5275
IGLV1-51	-5257
IGKC	-5210
IGKV1D-39	-4621
IGKV1-12	-4498
C1QA	-3836
IGHV4-34	-3644
MASP2	-2462
IGLV1-44	-1280
IGHV3-48	-616
IGKV1-16	-593
COLEC11	-442
IGHV3-23	658
IGKV1-33	3826
FCN1	7408
FCN3	9028

---

Cap-dependent Translation Initiation

Cap-dependent Translation Initiation

	152
set	Cap-dependent Translation Initiation
setSize	118
pANOVA	1.21e-18
s.dist	-0.469
p.adjustANOVA	2.52e-16

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS4X	-9157
RPLP2	-8715
EIF3F	-8575
RPL3	-8564
EIF2B4	-8482
RPL23	-8406
EIF3D	-8286
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
PABPC1	-7807
RPL26L1	-7694
UBA52	-7643
RPS5	-7633

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS4X	-9157
RPLP2	-8715
EIF3F	-8575
RPL3	-8564
EIF2B4	-8482
RPL23	-8406
EIF3D	-8286
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
PABPC1	-7807
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
EIF3L	-7612
EIF4H	-7534
RPL13	-7472
RPS18	-7468
EIF4EBP1	-7403
RPL7A	-7394
RPS16	-7390
RPS10	-7354
RPL26	-7340
RPL10A	-7253
RPL30	-7217
RPS11	-7138
RPL4	-7127
FAU	-7067
RPL13A	-7019
EIF3C	-7000
EIF2B1	-6963
EIF3B	-6904
RPS17	-6903
EIF3A	-6833
EIF2B2	-6805
RPS15	-6758
RPL29	-6731
RPL36AL	-6668
EIF3H	-6622
RPS20	-6537
RPL38	-6495
RPL12	-6483
RPLP0	-6397
RPL10	-6333
RPL8	-6300
RPL5	-6221
EIF3G	-6151
RPL37A	-6135
RPL27A	-6113
RPS2	-5959
RPS8	-5958
EIF3I	-5930
RPS21	-5899
RPL11	-5867
RPS27	-5866
RPLP1	-5846
RPS6	-5819
RPL17	-5749
EIF4B	-5716
RPL15	-5698
EIF2B3	-5607
RPL32	-5598
RPL41	-5397
RPL18	-5360
RPL23A	-5246
RPL34	-5148
RPL7	-5057
RPL18A	-5015
RPL6	-4942
RPS23	-4940
RPS19	-4848
RPS3	-4842
EIF2B5	-4742
RPL14	-4555
RPS15A	-4165
EIF3K	-3994
RPL27	-3935
RPL35	-3792
RPL39L	-3699
RPL39	-3539
EIF4A1	-3326
EIF2S2	-3286
RPS9	-3253
RPS24	-3138
EIF3M	-3135
RPS29	-3082
EIF4G1	-2994
RPS27A	-2058
RPL35A	-1829
RPS4Y1	-1198
RPS25	-545
RPL21	-383
RPS3A	-334
RPS13	-295
RPSA	-148
EIF2S3	-66
RPS7	1197
RPS27L	1251
RPL22	1273
RPL24	1297
EIF5	2871
EIF5B	3268
RPL3L	3763
EIF2S1	4031
EIF3E	4397
EIF4A2	4494
EIF3J	4622
EIF1AX	4832
EIF4E	5439
RPL9	6370
RPL22L1	6595
RPL36A	6879

---

Eukaryotic Translation Initiation

Eukaryotic Translation Initiation

	372
set	Eukaryotic Translation Initiation
setSize	118
pANOVA	1.21e-18
s.dist	-0.469
p.adjustANOVA	2.52e-16

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS4X	-9157
RPLP2	-8715
EIF3F	-8575
RPL3	-8564
EIF2B4	-8482
RPL23	-8406
EIF3D	-8286
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
PABPC1	-7807
RPL26L1	-7694
UBA52	-7643
RPS5	-7633

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS4X	-9157
RPLP2	-8715
EIF3F	-8575
RPL3	-8564
EIF2B4	-8482
RPL23	-8406
EIF3D	-8286
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
PABPC1	-7807
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
EIF3L	-7612
EIF4H	-7534
RPL13	-7472
RPS18	-7468
EIF4EBP1	-7403
RPL7A	-7394
RPS16	-7390
RPS10	-7354
RPL26	-7340
RPL10A	-7253
RPL30	-7217
RPS11	-7138
RPL4	-7127
FAU	-7067
RPL13A	-7019
EIF3C	-7000
EIF2B1	-6963
EIF3B	-6904
RPS17	-6903
EIF3A	-6833
EIF2B2	-6805
RPS15	-6758
RPL29	-6731
RPL36AL	-6668
EIF3H	-6622
RPS20	-6537
RPL38	-6495
RPL12	-6483
RPLP0	-6397
RPL10	-6333
RPL8	-6300
RPL5	-6221
EIF3G	-6151
RPL37A	-6135
RPL27A	-6113
RPS2	-5959
RPS8	-5958
EIF3I	-5930
RPS21	-5899
RPL11	-5867
RPS27	-5866
RPLP1	-5846
RPS6	-5819
RPL17	-5749
EIF4B	-5716
RPL15	-5698
EIF2B3	-5607
RPL32	-5598
RPL41	-5397
RPL18	-5360
RPL23A	-5246
RPL34	-5148
RPL7	-5057
RPL18A	-5015
RPL6	-4942
RPS23	-4940
RPS19	-4848
RPS3	-4842
EIF2B5	-4742
RPL14	-4555
RPS15A	-4165
EIF3K	-3994
RPL27	-3935
RPL35	-3792
RPL39L	-3699
RPL39	-3539
EIF4A1	-3326
EIF2S2	-3286
RPS9	-3253
RPS24	-3138
EIF3M	-3135
RPS29	-3082
EIF4G1	-2994
RPS27A	-2058
RPL35A	-1829
RPS4Y1	-1198
RPS25	-545
RPL21	-383
RPS3A	-334
RPS13	-295
RPSA	-148
EIF2S3	-66
RPS7	1197
RPS27L	1251
RPL22	1273
RPL24	1297
EIF5	2871
EIF5B	3268
RPL3L	3763
EIF2S1	4031
EIF3E	4397
EIF4A2	4494
EIF3J	4622
EIF1AX	4832
EIF4E	5439
RPL9	6370
RPL22L1	6595
RPL36A	6879

---

Regulation of Complement cascade

Regulation of Complement cascade

	1014
set	Regulation of Complement cascade
setSize	78
pANOVA	1.86e-18
s.dist	-0.574
p.adjustANOVA	3.38e-16

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
C6	-9502
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
C6	-9502
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
SERPING1	-9016
IGHG2	-9010
IGHV3-30	-8906
C2	-8903
IGHG3	-8775
IGLV1-47	-8713
C1R	-8672
IGLV3-21	-8651
IGKV3-15	-8522
CD81	-8477
IGHG4	-8417
IGKV3-20	-8400
C3AR1	-8279
C1QC	-8135
IGLV2-23	-8106
IGLV3-19	-7984
IGHV4-59	-7466
CFH	-7423
CFB	-7163
C4A	-7114
IGKV2-30	-7018
CD55	-6985
IGKV4-1	-6785
C1S	-6748
C1QB	-6698
IGLV6-57	-6578
C4B	-6148
C3	-5996
IGLV1-40	-5992
IGHV4-39	-5760
IGKV2D-28	-5697
IGHV1-2	-5528
IGHG1	-5275
IGLV1-51	-5257
IGKC	-5210
ELANE	-5060
C8G	-4781
IGKV1D-39	-4621
C4BPB	-4551
IGKV1-12	-4498
C5	-4419
C1QA	-3836
IGHV4-34	-3644
C7	-1618
CLU	-1592
IGLV1-44	-1280
IGHV3-48	-616
IGKV1-16	-593
IGHV3-23	658
IGKV1-33	3826
C5AR1	5732
CD46	5786
C5AR2	5819
CD59	6007
PROS1	6289
CR1	7735
CFI	7832
CPN2	7996

---

Binding and Uptake of Ligands by Scavenger Receptors

Binding and Uptake of Ligands by Scavenger Receptors

	114
set	Binding and Uptake of Ligands by Scavenger Receptors
setSize	82
pANOVA	2.24e-18
s.dist	-0.558
p.adjustANOVA	3.63e-16

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MARCO	-9567
SCARA5	-9547
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
SSC5D	-9274
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MARCO	-9567
SCARA5	-9547
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
SSC5D	-9274
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
COLEC12	-8917
IGHV3-30	-8906
MASP1	-8868
IGLV1-47	-8713
IGLV3-21	-8651
STAB1	-8531
IGKV3-15	-8522
IGKV3-20	-8400
COL1A1	-8334
LRP1	-8228
COL1A2	-8169
IGLV2-23	-8106
IGHA2	-8079
CD163	-8028
IGLV3-19	-7984
HYOU1	-7602
IGHV4-59	-7466
SCARB1	-7020
IGKV2-30	-7018
COL3A1	-6917
CALR	-6854
IGKV4-1	-6785
IGLV6-57	-6578
FTH1	-6184
IGLV1-40	-5992
IGHV4-39	-5760
IGKV2D-28	-5697
IGHV1-2	-5528
IGLV1-51	-5257
IGKC	-5210
IGHA1	-4732
IGKV1D-39	-4621
IGKV1-12	-4498
IGHV4-34	-3644
COL4A2	-2955
HSP90AA1	-2745
APOB	-2510
SPARC	-2377
FTL	-2370
HSP90B1	-2260
MSR1	-1454
IGLV1-44	-1280
APOE	-966
IGHV3-48	-616
IGKV1-16	-593
COLEC11	-442
HBB	-144
HBA1	-36
COL4A1	563
HSPH1	598
IGHV3-23	658
STAB2	887
JCHAIN	977
APOL1	2416
SAA1	2433
SCARF1	3012
HP	3247
IGKV1-33	3826
HPX	4539
CD36	5193

---

Major pathway of rRNA processing in the nucleolus and cytosol

Major pathway of rRNA processing in the nucleolus and cytosol

	660
set	Major pathway of rRNA processing in the nucleolus and cytosol
setSize	180
pANOVA	2.66e-18
s.dist	-0.377
p.adjustANOVA	3.86e-16

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PWP2	-9356
NOL12	-9160
RPS4X	-9157
PES1	-9076
WDR46	-9022
DHX37	-8992
UTP3	-8901
FTSJ3	-8731
RPLP2	-8715
RRP9	-8711
RPP25	-8676
NOB1	-8667
EXOSC7	-8626
RPL3	-8564
NOL6	-8490
RPP38	-8462
RPL23	-8406
RPS14	-8278
DDX49	-8262
RPS12	-8256

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PWP2	-9356
NOL12	-9160
RPS4X	-9157
PES1	-9076
WDR46	-9022
DHX37	-8992
UTP3	-8901
FTSJ3	-8731
RPLP2	-8715
RRP9	-8711
RPP25	-8676
NOB1	-8667
EXOSC7	-8626
RPL3	-8564
NOL6	-8490
RPP38	-8462
RPL23	-8406
RPS14	-8278
DDX49	-8262
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RRP1	-7943
RPL37	-7930
RPP21	-7916
RPS26	-7908
RPL31	-7842
LAS1L	-7790
WDR18	-7755
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
EBNA1BP2	-7528
CSNK1E	-7502
RPL13	-7472
RPS18	-7468
RPL7A	-7394
RPS16	-7390
NCL	-7363
RPS10	-7354
RPL26	-7340
RPL10A	-7253
RPL30	-7217
TBL3	-7214
BMS1	-7180
RPS11	-7138
RPL4	-7127
FAU	-7067
RPL13A	-7019
NOP14	-6926
RPS17	-6903
EXOSC2	-6796
RPS15	-6758
RPL29	-6731
RPL36AL	-6668
UTP14A	-6554
RPS20	-6537
RPL38	-6495
RPL12	-6483
CSNK1D	-6427
RPLP0	-6397
FBL	-6366
RPL10	-6333
RPL8	-6300
RPL5	-6221
EXOSC1	-6182
RPL37A	-6135
RPL27A	-6113
RRP36	-6103
RPS2	-5959
RPS8	-5958
NOC4L	-5927
RPS21	-5899
RPL11	-5867
RPS27	-5866
RPLP1	-5846
RPS6	-5819
UTP4	-5802
RPL17	-5749
RPL15	-5698
EXOSC10	-5673
RPL32	-5598
IMP4	-5469
RPL41	-5397
BOP1	-5385
RPL18	-5360
EXOSC4	-5333
IMP3	-5301
RCL1	-5265
RPL23A	-5246
RPL34	-5148
RPL7	-5057
RPL18A	-5015
PELP1	-5004
RPL6	-4942
RPS23	-4940
RPS19	-4848
RPS3	-4842
NOP56	-4726
SNU13	-4584
RPL14	-4555
RPS15A	-4165
EMG1	-3956
RPL27	-3935
RPL35	-3792
RPL39L	-3699
RPL39	-3539
RPS9	-3253
UTP25	-3217
EXOSC5	-3179
BYSL	-3140
RPS24	-3138
RPS29	-3082
PDCD11	-2693
EXOSC3	-2536
WDR12	-2378
UTP18	-2303
RPS27A	-2058
TSR1	-2001
RPP40	-1863
EXOSC6	-1847
RPL35A	-1829
RRP7A	-1767
RBM28	-1756
NIP7	-1693
XRN2	-1560
SENP3	-1401
GNL3	-1329
LTV1	-1318
RPS4Y1	-1198
RIOK2	-891
UTP14C	-777
RPS25	-545
DCAF13	-448
RPL21	-383
RPS3A	-334
RPS13	-295
RPSA	-148
NOL11	-105
UTP20	94
WDR43	176
ISG20L2	384
DDX47	693
PNO1	843
WDR3	916
RPS7	1197
RPS27L	1251
RPL22	1273
RPL24	1297
RIOK1	1448
NOL9	1697
EXOSC9	1963
UTP6	2380
DIS3	2583
FCF1	2588
EXOSC8	2653
RPP14	2689
HEATR1	2886
MTREX	3201
ERI1	3312
RPL3L	3763
RPP30	3814
NOP58	4137
TEX10	4243
MPHOSPH6	4600
WDR75	4848
UTP11	5716
WDR36	5894
RIOK3	6036
KRR1	6130
MPHOSPH10	6348
RPL9	6370
DDX21	6458
RPL22L1	6595
UTP15	6799
RPL36A	6879
DDX52	6981
C1D	8221

---

Translation

Translation

	1358
set	Translation
setSize	294
pANOVA	3.64e-18
s.dist	-0.295
p.adjustANOVA	4.81e-16

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS4X	-9157
EEF1A1P5	-8817
RPLP2	-8715
EIF3F	-8575
RPL3	-8564
EIF2B4	-8482
VARS2	-8475
RPL23	-8406
MRPS21	-8343
EEF1A1	-8291
EIF3D	-8286
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
EEF2	-8011
RPL37	-7930
RPS26	-7908

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS4X	-9157
EEF1A1P5	-8817
RPLP2	-8715
EIF3F	-8575
RPL3	-8564
EIF2B4	-8482
VARS2	-8475
RPL23	-8406
MRPS21	-8343
EEF1A1	-8291
EIF3D	-8286
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
EEF2	-8011
RPL37	-7930
RPS26	-7908
RPL31	-7842
PABPC1	-7807
RPL26L1	-7694
SEC61A1	-7668
UBA52	-7643
RPS5	-7633
EIF3L	-7612
EIF4H	-7534
SSR4	-7533
SARS1	-7485
RPL13	-7472
RPS18	-7468
EIF4EBP1	-7403
RPL7A	-7394
RPS16	-7390
MRPL11	-7366
RPS10	-7354
RPL26	-7340
MRPL10	-7327
MRPS2	-7311
TARS1	-7290
MRPL55	-7255
RPL10A	-7253
RPN1	-7232
RPL30	-7217
FARSA	-7178
RPS11	-7138
RPL4	-7127
FAU	-7067
RPL13A	-7019
EIF3C	-7000
EIF2B1	-6963
MRPS34	-6940
EIF3B	-6904
RPS17	-6903
EIF3A	-6833
EEF1D	-6807
EIF2B2	-6805
RPS15	-6758
SARS2	-6738
RPL29	-6731
SSR2	-6727
QARS1	-6720
TRMT112	-6708
SRP68	-6707
RPL36AL	-6668
WARS2	-6649
EIF3H	-6622
SRPRA	-6577
MRPS26	-6541
RPS20	-6537
MRPS18A	-6516
RPL38	-6495
RPL12	-6483
RPLP0	-6397
RPL10	-6333
MARS1	-6302
RPL8	-6300
RPL5	-6221
AARS2	-6193
EIF3G	-6151
RPL37A	-6135
HARS1	-6131
RPL27A	-6113
SRPRB	-6094
DDOST	-6043
VARS1	-6028
MRPS12	-5969
RPS2	-5959
RPS8	-5958
EIF3I	-5930
RPS21	-5899
CARS1	-5897
MRPL43	-5872
RPL11	-5867
RPS27	-5866
RPLP1	-5846
MRPL17	-5823
RPS6	-5819
YARS2	-5818
MRPL36	-5798
MRPL53	-5769
RPL17	-5749
EIF4B	-5716
RPL15	-5698
TUFM	-5629
EIF2B3	-5607
RPL32	-5598
RPN2	-5586
OXA1L	-5523
AARS1	-5489
MRPL58	-5444
RPL41	-5397
DAP3	-5381
MRPL23	-5374
RPL18	-5360
FARS2	-5324
MRPL24	-5322
RPL23A	-5246
RPL34	-5148
RPL7	-5057
RPL18A	-5015
ERAL1	-5008
RPL6	-4942
RPS23	-4940
RPS19	-4848
RPS3	-4842
MRPL38	-4830
EIF2B5	-4742
TSFM	-4733
MRPL41	-4655
RPL14	-4555
MRPL27	-4538
MRPL9	-4469
MRPL45	-4373
MRPS11	-4302
MRPL28	-4300
MRPL20	-4223
RPS15A	-4165
MTIF2	-4162
MRPL49	-4100
MRPL57	-4040
MRPL4	-4016
EEF1B2	-4009
MRPL2	-3998
EIF3K	-3994
CHCHD1	-3987
RPL27	-3935
GARS1	-3821
RPL35	-3792
MRPL54	-3772
SEC61B	-3730
RPL39L	-3699
GSPT2	-3673
MRPS15	-3557
RPL39	-3539
EIF4A1	-3326
EIF2S2	-3286
KARS1	-3275
MRPL21	-3274
RPS9	-3253
MRPL14	-3203
MRPS5	-3139
RPS24	-3138
EIF3M	-3135
MRPL46	-3113
RPS29	-3082
SRP72	-3081
EEF1G	-3076
MRPL32	-3073
EIF4G1	-2994
MRPL37	-2829
MRPS7	-2694
MRPS22	-2680
APEH	-2675
MRPS16	-2634
MRPS18B	-2540
MRPL16	-2436
MRPS24	-2434
CARS2	-2419
GADD45GIP1	-2336
MRPS33	-2194
YARS1	-2138
MRPS36	-2108
RPS27A	-2058
MRPL3	-1957
MRPL22	-1910
NARS1	-1872
RPL35A	-1829
SEC11C	-1765
N6AMT1	-1634
SRP14	-1521
SSR3	-1475
MRPL40	-1469
MRPS14	-1377
AURKAIP1	-1200
RPS4Y1	-1198
NARS2	-1187
HARS2	-1040
MRPL35	-1031
MRPS27	-743
PARS2	-726
EARS2	-691
IARS1	-664
RPS25	-545
EPRS1	-493
RPL21	-383
MRRF	-342
RPS3A	-334
TARS2	-330
RPS13	-295
MTIF3	-276
MRPL12	-254
RPSA	-148
RARS1	-147
EIF2S3	-66
MRPL52	-64
LARS2	-17
MRPS23	66
MRPL15	169
MRPL51	255
MRPL34	323
SEC11A	395
MRPL39	575
MRPL48	773
MARS2	859
MRPS17	938
MRPL18	949
FARSB	1015
SSR1	1039
PTCD3	1050
AIMP1	1167
RPS7	1197
ETF1	1218
RPS27L	1251
RPL22	1273
RPL24	1297
EEF1A2	1298
MRPS18C	1328
MRPL47	1358
IARS2	1417
MRPS30	2070
MRPS9	2089
GSPT1	2097
SRP19	2192
MRPL13	2204
MRPS25	2319
MRPS31	2484
AIMP2	2640
DARS1	2769
PPA1	2829
EIF5	2871
MRPS6	2968
RARS2	3011
GFM2	3176
MTFMT	3212
EIF5B	3268
MRPL44	3308
SEC61A2	3459
MRPL30	3540
RPL3L	3763
MRPS35	3764
MRPS28	3787
DARS2	3886
EIF2S1	4031
SRP9	4038
SPCS1	4118
SRP54	4227
MRPS10	4381
EIF3E	4397
SEC61G	4453
EIF4A2	4494
SPCS2	4543
TRAM1	4548
EIF3J	4622
GFM1	4689
EIF1AX	4832
MRPL33	5081
WARS1	5297
EIF4E	5439
PPA2	5481
MRPL1	5656
MRPL50	5689
EEF1E1	5800
MRPL19	5890
LARS1	6265
RPL9	6370
RPL22L1	6595
RPL36A	6879
MTRF1L	6924
MRPL42	7230
MT-RNR1	7788
SPCS3	8030
MT-RNR2	9249

---

Formation of a pool of free 40S subunits

Formation of a pool of free 40S subunits

	420
set	Formation of a pool of free 40S subunits
setSize	100
pANOVA	4.67e-18
s.dist	-0.501
p.adjustANOVA	5.66e-16

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS4X	-9157
RPLP2	-8715
EIF3F	-8575
RPL3	-8564
RPL23	-8406
EIF3D	-8286
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
EIF3L	-7612
RPL13	-7472

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS4X	-9157
RPLP2	-8715
EIF3F	-8575
RPL3	-8564
RPL23	-8406
EIF3D	-8286
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
EIF3L	-7612
RPL13	-7472
RPS18	-7468
RPL7A	-7394
RPS16	-7390
RPS10	-7354
RPL26	-7340
RPL10A	-7253
RPL30	-7217
RPS11	-7138
RPL4	-7127
FAU	-7067
RPL13A	-7019
EIF3C	-7000
EIF3B	-6904
RPS17	-6903
EIF3A	-6833
RPS15	-6758
RPL29	-6731
RPL36AL	-6668
EIF3H	-6622
RPS20	-6537
RPL38	-6495
RPL12	-6483
RPLP0	-6397
RPL10	-6333
RPL8	-6300
RPL5	-6221
EIF3G	-6151
RPL37A	-6135
RPL27A	-6113
RPS2	-5959
RPS8	-5958
EIF3I	-5930
RPS21	-5899
RPL11	-5867
RPS27	-5866
RPLP1	-5846
RPS6	-5819
RPL17	-5749
RPL15	-5698
RPL32	-5598
RPL41	-5397
RPL18	-5360
RPL23A	-5246
RPL34	-5148
RPL7	-5057
RPL18A	-5015
RPL6	-4942
RPS23	-4940
RPS19	-4848
RPS3	-4842
RPL14	-4555
RPS15A	-4165
EIF3K	-3994
RPL27	-3935
RPL35	-3792
RPL39L	-3699
RPL39	-3539
RPS9	-3253
RPS24	-3138
EIF3M	-3135
RPS29	-3082
RPS27A	-2058
RPL35A	-1829
RPS4Y1	-1198
RPS25	-545
RPL21	-383
RPS3A	-334
RPS13	-295
RPSA	-148
RPS7	1197
RPS27L	1251
RPL22	1273
RPL24	1297
RPL3L	3763
EIF3E	4397
EIF3J	4622
EIF1AX	4832
RPL9	6370
RPL22L1	6595
RPL36A	6879

---

Eukaryotic Translation Elongation

Eukaryotic Translation Elongation

	371
set	Eukaryotic Translation Elongation
setSize	93
pANOVA	6.85e-18
s.dist	-0.517
p.adjustANOVA	7.67e-16

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS4X	-9157
EEF1A1P5	-8817
RPLP2	-8715
RPL3	-8564
RPL23	-8406
EEF1A1	-8291
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
EEF2	-8011
RPL37	-7930
RPS26	-7908
RPL31	-7842
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
RPL13	-7472

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS4X	-9157
EEF1A1P5	-8817
RPLP2	-8715
RPL3	-8564
RPL23	-8406
EEF1A1	-8291
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
EEF2	-8011
RPL37	-7930
RPS26	-7908
RPL31	-7842
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
RPL13	-7472
RPS18	-7468
RPL7A	-7394
RPS16	-7390
RPS10	-7354
RPL26	-7340
RPL10A	-7253
RPL30	-7217
RPS11	-7138
RPL4	-7127
FAU	-7067
RPL13A	-7019
RPS17	-6903
EEF1D	-6807
RPS15	-6758
RPL29	-6731
RPL36AL	-6668
RPS20	-6537
RPL38	-6495
RPL12	-6483
RPLP0	-6397
RPL10	-6333
RPL8	-6300
RPL5	-6221
RPL37A	-6135
RPL27A	-6113
RPS2	-5959
RPS8	-5958
RPS21	-5899
RPL11	-5867
RPS27	-5866
RPLP1	-5846
RPS6	-5819
RPL17	-5749
RPL15	-5698
RPL32	-5598
RPL41	-5397
RPL18	-5360
RPL23A	-5246
RPL34	-5148
RPL7	-5057
RPL18A	-5015
RPL6	-4942
RPS23	-4940
RPS19	-4848
RPS3	-4842
RPL14	-4555
RPS15A	-4165
EEF1B2	-4009
RPL27	-3935
RPL35	-3792
RPL39L	-3699
RPL39	-3539
RPS9	-3253
RPS24	-3138
RPS29	-3082
EEF1G	-3076
RPS27A	-2058
RPL35A	-1829
RPS4Y1	-1198
RPS25	-545
RPL21	-383
RPS3A	-334
RPS13	-295
RPSA	-148
RPS7	1197
RPS27L	1251
RPL22	1273
RPL24	1297
EEF1A2	1298
RPL3L	3763
RPL9	6370
RPL22L1	6595
RPL36A	6879

---

L13a-mediated translational silencing of Ceruloplasmin expression

L13a-mediated translational silencing of Ceruloplasmin expression

	620
set	L13a-mediated translational silencing of Ceruloplasmin expression
setSize	110
pANOVA	1.3e-17
s.dist	-0.471
p.adjustANOVA	1.35e-15

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS4X	-9157
RPLP2	-8715
EIF3F	-8575
RPL3	-8564
RPL23	-8406
EIF3D	-8286
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
PABPC1	-7807
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
EIF3L	-7612

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS4X	-9157
RPLP2	-8715
EIF3F	-8575
RPL3	-8564
RPL23	-8406
EIF3D	-8286
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
PABPC1	-7807
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
EIF3L	-7612
EIF4H	-7534
RPL13	-7472
RPS18	-7468
RPL7A	-7394
RPS16	-7390
RPS10	-7354
RPL26	-7340
RPL10A	-7253
RPL30	-7217
RPS11	-7138
RPL4	-7127
FAU	-7067
RPL13A	-7019
EIF3C	-7000
EIF3B	-6904
RPS17	-6903
EIF3A	-6833
RPS15	-6758
RPL29	-6731
RPL36AL	-6668
EIF3H	-6622
RPS20	-6537
RPL38	-6495
RPL12	-6483
RPLP0	-6397
RPL10	-6333
RPL8	-6300
RPL5	-6221
EIF3G	-6151
RPL37A	-6135
RPL27A	-6113
RPS2	-5959
RPS8	-5958
EIF3I	-5930
RPS21	-5899
RPL11	-5867
RPS27	-5866
RPLP1	-5846
RPS6	-5819
RPL17	-5749
EIF4B	-5716
RPL15	-5698
RPL32	-5598
RPL41	-5397
RPL18	-5360
RPL23A	-5246
RPL34	-5148
RPL7	-5057
RPL18A	-5015
RPL6	-4942
RPS23	-4940
RPS19	-4848
RPS3	-4842
RPL14	-4555
RPS15A	-4165
EIF3K	-3994
RPL27	-3935
RPL35	-3792
RPL39L	-3699
RPL39	-3539
EIF4A1	-3326
EIF2S2	-3286
RPS9	-3253
RPS24	-3138
EIF3M	-3135
RPS29	-3082
EIF4G1	-2994
RPS27A	-2058
RPL35A	-1829
RPS4Y1	-1198
RPS25	-545
RPL21	-383
RPS3A	-334
RPS13	-295
RPSA	-148
EIF2S3	-66
RPS7	1197
RPS27L	1251
RPL22	1273
RPL24	1297
RPL3L	3763
EIF2S1	4031
EIF3E	4397
EIF4A2	4494
EIF3J	4622
EIF1AX	4832
EIF4E	5439
RPL9	6370
RPL22L1	6595
RPL36A	6879

---

Complement cascade

Complement cascade

	211
set	Complement cascade
setSize	86
pANOVA	2.52e-17
s.dist	-0.528
p.adjustANOVA	2.45e-15

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
C6	-9502
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
CFD	-9361
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
C6	-9502
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
CFD	-9361
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
SERPING1	-9016
IGHG2	-9010
IGHV3-30	-8906
C2	-8903
MASP1	-8868
IGHG3	-8775
IGLV1-47	-8713
C1R	-8672
IGLV3-21	-8651
IGKV3-15	-8522
CD81	-8477
IGHG4	-8417
IGKV3-20	-8400
C3AR1	-8279
C1QC	-8135
IGLV2-23	-8106
IGLV3-19	-7984
IGHV4-59	-7466
CFH	-7423
CFB	-7163
C4A	-7114
IGKV2-30	-7018
CD55	-6985
IGKV4-1	-6785
C1S	-6748
C1QB	-6698
IGLV6-57	-6578
C4B	-6148
FCN2	-6048
C3	-5996
IGLV1-40	-5992
IGHV4-39	-5760
IGKV2D-28	-5697
IGHV1-2	-5528
IGHG1	-5275
IGLV1-51	-5257
IGKC	-5210
ELANE	-5060
C8G	-4781
IGKV1D-39	-4621
C4BPB	-4551
IGKV1-12	-4498
C5	-4419
C1QA	-3836
IGHV4-34	-3644
MASP2	-2462
C7	-1618
CLU	-1592
IGLV1-44	-1280
IGHV3-48	-616
IGKV1-16	-593
COLEC11	-442
IGHV3-23	658
IGKV1-33	3826
GZMM	4366
C5AR1	5732
CD46	5786
C5AR2	5819
CD59	6007
PROS1	6289
FCN1	7408
CR1	7735
CFI	7832
CPN2	7996
FCN3	9028

---

Peptide chain elongation

Peptide chain elongation

	844
set	Peptide chain elongation
setSize	88
pANOVA	3.02e-17
s.dist	-0.521
p.adjustANOVA	2.72e-15

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS4X	-9157
RPLP2	-8715
RPL3	-8564
RPL23	-8406
EEF1A1	-8291
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
EEF2	-8011
RPL37	-7930
RPS26	-7908
RPL31	-7842
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
RPL13	-7472
RPS18	-7468

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS4X	-9157
RPLP2	-8715
RPL3	-8564
RPL23	-8406
EEF1A1	-8291
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
EEF2	-8011
RPL37	-7930
RPS26	-7908
RPL31	-7842
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
RPL13	-7472
RPS18	-7468
RPL7A	-7394
RPS16	-7390
RPS10	-7354
RPL26	-7340
RPL10A	-7253
RPL30	-7217
RPS11	-7138
RPL4	-7127
FAU	-7067
RPL13A	-7019
RPS17	-6903
RPS15	-6758
RPL29	-6731
RPL36AL	-6668
RPS20	-6537
RPL38	-6495
RPL12	-6483
RPLP0	-6397
RPL10	-6333
RPL8	-6300
RPL5	-6221
RPL37A	-6135
RPL27A	-6113
RPS2	-5959
RPS8	-5958
RPS21	-5899
RPL11	-5867
RPS27	-5866
RPLP1	-5846
RPS6	-5819
RPL17	-5749
RPL15	-5698
RPL32	-5598
RPL41	-5397
RPL18	-5360
RPL23A	-5246
RPL34	-5148
RPL7	-5057
RPL18A	-5015
RPL6	-4942
RPS23	-4940
RPS19	-4848
RPS3	-4842
RPL14	-4555
RPS15A	-4165
RPL27	-3935
RPL35	-3792
RPL39L	-3699
RPL39	-3539
RPS9	-3253
RPS24	-3138
RPS29	-3082
RPS27A	-2058
RPL35A	-1829
RPS4Y1	-1198
RPS25	-545
RPL21	-383
RPS3A	-334
RPS13	-295
RPSA	-148
RPS7	1197
RPS27L	1251
RPL22	1273
RPL24	1297
RPL3L	3763
RPL9	6370
RPL22L1	6595
RPL36A	6879

---

Metabolism of proteins

Metabolism of proteins

	682
set	Metabolism of proteins
setSize	1690
pANOVA	3.17e-17
s.dist	-0.124
p.adjustANOVA	2.72e-15

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GFPT2	-9551
SPSB4	-9546
MUC20	-9538
MMP2	-9518
MUC6	-9492
MELTF	-9488
FBN1	-9462
GALNT16	-9461
THBS2	-9455
GALNT8	-9442
F10	-9439
PENK	-9428
MUC12	-9426
GSN	-9425
SPSB1	-9417
FSTL1	-9413
PGA3	-9409
MDGA1	-9395
TGFBI	-9390
RAB44	-9385

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GFPT2	-9551.0
SPSB4	-9546.0
MUC20	-9538.0
MMP2	-9518.0
MUC6	-9492.0
MELTF	-9488.0
FBN1	-9462.0
GALNT16	-9461.0
THBS2	-9455.0
GALNT8	-9442.0
F10	-9439.0
PENK	-9428.0
MUC12	-9426.0
GSN	-9425.0
SPSB1	-9417.0
FSTL1	-9413.0
PGA3	-9409.0
MDGA1	-9395.0
TGFBI	-9390.0
RAB44	-9385.0
FN1	-9363.0
H2BC12	-9313.0
CPM	-9309.0
IGFBP6	-9289.0
FOLR2	-9285.0
XPNPEP2	-9273.0
KDELR3	-9269.0
UAP1	-9261.0
ADAMTSL4	-9245.0
FAM20A	-9227.0
XPC	-9217.0
ANPEP	-9215.0
B3GNT9	-9214.0
CDKN2A	-9194.0
H2AW	-9173.0
RPS4X	-9157.0
CTSG	-9144.0
SMAD7	-9122.0
FBXW9	-9094.0
MFGE8	-9081.0
SDC2	-9050.0
TUBB6	-9028.0
BET1L	-9024.0
AAAS	-9006.0
POMT2	-8968.0
GALNT12	-8937.0
RTN4RL2	-8893.0
SPON2	-8862.0
AMDHD2	-8856.0
FBXW4	-8849.0
BPIFB2	-8840.0
CMA1	-8824.0
GMPPB	-8822.0
EEF1A1P5	-8817.0
SLC35C1	-8814.0
ENGASE	-8803.0
ADAMTS13	-8796.0
CTSZ	-8730.0
MXRA8	-8725.0
KDELR1	-8717.0
RPLP2	-8715.0
DPM2	-8704.0
ACTR8	-8671.0
FN3KRP	-8668.0
CPA3	-8666.0
NTM	-8662.0
DCAF4	-8604.0
PRKCSH	-8602.0
CUL7	-8598.0
MOGS	-8596.0
EIF3F	-8575.0
RNF181	-8574.0
TSPAN15	-8572.0
GGA3	-8567.0
RPL3	-8564.0
FBXL12	-8542.0
KCTD7	-8541.0
ARFGAP1	-8534.0
PIGT	-8502.0
INO80E	-8493.0
OTUD5	-8487.0
PIGQ	-8485.0
EIF2B4	-8482.0
COPG2	-8478.0
VARS2	-8475.0
ABCA3	-8474.0
SEC13	-8457.0
GNA15	-8447.0
CDCA8	-8441.0
SPSB3	-8424.0
STX1A	-8416.0
RPL23	-8406.0
ADAMTS10	-8398.0
TFPT	-8363.0
ARSA	-8348.0
SELENOS	-8344.0
MRPS21	-8343.0
USP11	-8342.0
DPH7	-8338.0
ASB13	-8336.0
DDB2	-8333.0
RING1	-8331.0
ALG3	-8328.0
SPON1	-8313.0
EEF1A1	-8291.0
EIF3D	-8286.0
HGS	-8283.0
RPS14	-8278.0
SYVN1	-8265.0
RAB17	-8261.0
RPS12	-8256.0
HDAC7	-8251.0
JOSD2	-8244.0
COMMD4	-8234.0
GALNT17	-8227.0
RNF40	-8202.0
HSPG2	-8195.0
DPH2	-8193.0
RPL36	-8166.0
TMEM115	-8152.0
USP4	-8150.0
RAB41	-8148.0
CHD3	-8140.0
RPL19	-8133.0
RPS28	-8128.0
ZBTB16	-8117.0
THRA	-8098.0
DCTN1	-8089.0
DPP4	-8081.0
TNIP2	-8077.0
ST3GAL4	-8065.0
AGBL5	-8034.0
RPL28	-8031.0
RAB34	-8022.0
EEF2	-8011.0
CSF1	-7995.0
PMM2	-7976.0
TFG	-7967.0
CHRDL1	-7955.0
RAB11B	-7954.0
MTA1	-7942.0
GAS6	-7940.0
RPL37	-7930.0
PFDN2	-7923.0
RPS26	-7908.0
NSMCE1	-7900.0
CHST10	-7880.0
CISH	-7878.0
CKAP4	-7849.0
RPL31	-7842.0
MRTFA	-7835.0
TPGS1	-7833.0
COPZ2	-7828.0
FUCA1	-7821.0
TMED9	-7815.0
PABPC1	-7807.0
OS9	-7797.0
FSTL3	-7794.0
KLHL22	-7778.0
CCT5	-7769.0
LGALS1	-7766.0
ADAMTS17	-7765.0
INO80B	-7746.0
PMM1	-7745.0
HDAC3	-7742.0
GOLGA2	-7731.0
TUBA1B	-7715.0
ALG12	-7699.0
RPL26L1	-7694.0
CFP	-7685.0
NUP188	-7684.0
SEC61A1	-7668.0
ADAMTS16	-7666.0
UBA52	-7643.0
DAXX	-7642.0
ADAMTS2	-7639.0
RPS5	-7633.0
ASB6	-7623.0
PSMA7	-7617.0
EIF3L	-7612.0
GORASP1	-7588.0
PIGZ	-7581.0
PSMB7	-7580.0
RENBP	-7566.0
IKBKG	-7562.0
RAB35	-7555.0
CST3	-7553.0
TUBA1A	-7543.0
PSMC3	-7538.0
EIF4H	-7534.0
SSR4	-7533.0
GNB2	-7507.0
UBE2I	-7499.0
MPI	-7493.0
CCDC22	-7492.0
SARS1	-7485.0
MVD	-7481.0
BAP1	-7479.0
NANS	-7476.0
RPL13	-7472.0
GPS1	-7470.0
RPS18	-7468.0
FKBP8	-7444.0
FAM20C	-7443.0
GALNT10	-7422.0
SAE1	-7419.0
BACE1	-7412.0
IGFBP3	-7411.0
EIF4EBP1	-7403.0
DPM3	-7400.0
GMPPA	-7399.0
RPL7A	-7394.0
RPS16	-7390.0
TIMP1	-7382.0
CSNK2B	-7373.0
TRIM28	-7371.0
MRPL11	-7366.0
BMP4	-7365.0
RPS10	-7354.0
NUP85	-7351.0
PTRH2	-7350.0
POFUT2	-7347.0
RPA1	-7341.0
RPL26	-7340.0
COPE	-7337.0
GALNT15	-7333.0
FKBP9	-7330.0
MRPL10	-7327.0
TTLL1	-7324.0
MRPS2	-7311.0
TARS1	-7290.0
GPC3	-7281.0
CTBP1	-7277.0
ARF1	-7273.0
MRPL55	-7255.0
RPL10A	-7253.0
GALNT11	-7244.0
UBXN1	-7243.0
FBXO17	-7236.0
RPN1	-7232.0
RPL30	-7217.0
ST6GALNAC6	-7211.0
SPTBN1	-7208.0
ACTB	-7187.0
GANAB	-7181.0
FARSA	-7178.0
MBD1	-7176.0
TBC1D20	-7150.0
RPS11	-7138.0
PSMD4	-7134.0
RPL4	-7127.0
C4A	-7114.0
LMAN2	-7109.0
AXIN1	-7095.0
RAB7B	-7091.0
FAU	-7067.0
NUCB1	-7054.0
EXOC7	-7047.0
SEC31A	-7037.0
MUC4	-7036.0
RPL13A	-7019.0
KDELR2	-7005.0
CHST8	-7004.0
EIF3C	-7000.0
APH1A	-6986.0
CD55	-6985.0
CUL9	-6981.0
STAMBPL1	-6974.0
PGA5	-6969.0
FBXL18	-6967.0
EIF2B1	-6963.0
JOSD1	-6951.0
PSMC5	-6942.0
MRPS34	-6940.0
ADAMTS14	-6930.0
COPG1	-6927.0
SAFB	-6919.0
COPA	-6918.0
NFRKB	-6914.0
TTLL3	-6910.0
EIF3B	-6904.0
RPS17	-6903.0
SHISA5	-6893.0
CALR	-6854.0
STX5	-6846.0
GNB1	-6844.0
SUMF1	-6840.0
ZBED1	-6837.0
EIF3A	-6833.0
DDA1	-6820.0
EEF1D	-6807.0
EIF2B2	-6805.0
RAB40C	-6799.0
TRAPPC2L	-6791.0
APLP2	-6784.0
CTSA	-6775.0
ANO8	-6760.0
RPS15	-6758.0
CCT3	-6752.0
SARS2	-6738.0
RPL29	-6731.0
SSR2	-6727.0
MAVS	-6725.0
QARS1	-6720.0
SEC24C	-6711.0
TRMT112	-6708.0
SRP68	-6707.0
PSMD8	-6703.0
FBXW5	-6674.0
RPL36AL	-6668.0
POMGNT2	-6658.0
PIGY	-6656.5
WARS2	-6649.0
PFDN1	-6646.0
INHBB	-6632.0
EIF3H	-6622.0
GBA	-6620.0
SRPRA	-6577.0
TAB1	-6572.0
RAB32	-6555.0
CSF2RA	-6546.0
MRPS26	-6541.0
RPS20	-6537.0
B3GNT8	-6525.0
MRPS18A	-6516.0
GGA2	-6509.0
WDR5	-6507.0
RPL38	-6495.0
EDEM2	-6490.0
RPL12	-6483.0
TADA3	-6465.0
COPS7B	-6459.0
GOLM1	-6458.0
B3GNTL1	-6449.0
MGAT3	-6443.0
CSNK1D	-6427.0
ADRM1	-6426.0
PSMB4	-6417.0
ARL2	-6409.0
RPLP0	-6397.0
ARSI	-6394.0
KIFC3	-6373.0
B4GAT1	-6368.0
INO80	-6367.0
B3GNT7	-6363.0
ACE	-6350.0
RAET1G	-6344.0
RPL10	-6333.0
UBE2Z	-6326.0
A4GNT	-6324.0
COMMD6	-6323.0
RECK	-6316.0
MGAT4B	-6306.0
MARS1	-6302.0
RPL8	-6300.0
COMMD5	-6298.0
OTUB1	-6285.0
DOLK	-6281.0
TTLL11	-6273.0
CAPZB	-6272.0
TBCB	-6267.0
GGA1	-6262.0
POM121	-6225.0
RPL5	-6221.0
FBXL7	-6220.0
AARS2	-6193.0
PIGG	-6175.0
MAN1C1	-6164.0
EIF3G	-6151.0
RPL37A	-6135.0
TMED3	-6134.0
HARS1	-6131.0
RPL27A	-6113.0
PAF1	-6112.0
SCMH1	-6109.0
SRPRB	-6094.0
ADAMTSL1	-6076.0
ARF3	-6068.0
RAB23	-6060.0
PIGU	-6052.0
ANK2	-6049.0
FBXO41	-6044.0
DDOST	-6043.0
VARS1	-6028.0
PIAS4	-6009.0
TMEM129	-6007.0
AXIN2	-5999.0
C3	-5996.0
UBE2J2	-5984.0
L3MBTL2	-5981.0
MEN1	-5976.0
NCOR2	-5973.0
COPS6	-5971.0
FBXO31	-5970.0
MRPS12	-5969.0
FBXO44	-5968.0
RPS2	-5959.0
RPS8	-5958.0
GOLGB1	-5951.0
EIF3I	-5930.0
RPS21	-5899.0
CARS1	-5897.0
RNF135	-5889.0
MRPL43	-5872.0
DOHH	-5868.0
RPL11	-5867.0
RPS27	-5866.0
BABAM1	-5860.0
MAN1B1	-5852.0
PPARG	-5849.0
ARF5	-5847.0
RPLP1	-5846.0
ACTR5	-5832.0
MRPL17	-5823.0
RPS6	-5819.0
YARS2	-5818.0
USP20	-5813.0
MRPL36	-5798.0
MBTPS1	-5783.0
SIN3A	-5782.0
MRPL53	-5769.0
PSMD9	-5765.0
YKT6	-5757.0
RPL17	-5749.0
RAB13	-5745.0
GFUS	-5741.0
EIF4B	-5716.0
FOXK2	-5701.0
TRAPPC3	-5699.0
RPL15	-5698.0
TRAF3	-5679.0
USP5	-5662.0
NEDD8	-5659.0
ARFGAP2	-5642.0
TUFM	-5629.0
ASXL1	-5612.0
RNF20	-5611.0
EIF2B3	-5607.0
RPL32	-5598.0
MGAT1	-5591.0
RPN2	-5586.0
ADAMTS7	-5570.0
LAMC1	-5561.0
FOXO4	-5542.0
OXA1L	-5523.0
PIGO	-5516.0
VCAN	-5502.0
PSMF1	-5494.0
AARS1	-5489.0
CREBBP	-5487.0
DCTN2	-5482.0
POMC	-5478.0
RUVBL1	-5477.0
LAMB2	-5465.0
TTLL12	-5461.0
RANGAP1	-5460.0
SUMF2	-5457.0
USP18	-5445.0
MRPL58	-5444.0
LTBP1	-5436.0
RAB1B	-5419.0
RBBP7	-5415.0
RPL41	-5397.0
DAP3	-5381.0
MRPL23	-5374.0
RPL18	-5360.0
ETFB	-5359.0
B4GALNT2	-5353.0
PIAS3	-5347.0
GPAA1	-5338.0
ALG1	-5332.0
PSMB3	-5327.0
FARS2	-5324.0
MRPL24	-5322.0
DDB1	-5308.0
CTSC	-5303.0
FBXW8	-5288.0
ELOB	-5284.0
GNPNAT1	-5273.0
PCNA	-5272.0
SPTAN1	-5267.0
RPL23A	-5246.0
PSMD3	-5235.0
CDC34	-5223.0
MPDU1	-5217.0
STT3A	-5213.0
B4GALT2	-5212.0
TRAPPC1	-5198.0
ING2	-5190.0
PSMB1	-5182.0
TRAPPC5	-5179.0
RPL34	-5148.0
PIGL	-5143.0
FBXO27	-5141.0
DNMT1	-5127.0
TTLL5	-5097.0
P4HB	-5094.0
FURIN	-5091.0
CTSH	-5082.0
ST6GALNAC4	-5073.0
PSMD7	-5070.0
SEC22C	-5067.0
RPL7	-5057.0
CCT7	-5038.0
RNF185	-5027.0
RIPK1	-5016.0
RPL18A	-5015.0
ERAL1	-5008.0
CTSD	-5002.0
PIGC	-4990.0
TNIP1	-4982.0
APP	-4981.0
MCRS1	-4962.0
PSMD14	-4951.0
PSMB10	-4948.0
RPL6	-4942.0
RPS23	-4940.0
ARRB1	-4930.0
SFTPD	-4929.0
DCTN5	-4917.0
MYO5A	-4904.0
PPP6R1	-4901.0
PSMC2	-4880.0
TTLL4	-4868.0
FBXL14	-4864.0
PSMB6	-4849.0
RPS19	-4848.0
PEX10	-4845.0
RXRA	-4843.0
RPS3	-4842.0
COPS7A	-4832.0
MRPL38	-4830.0
TRAPPC6A	-4822.0
COG1	-4818.0
CCT6A	-4807.0
FBXL15	-4806.0
FBXL8	-4805.0
ACTR1A	-4804.0
COPB2	-4799.0
GPIHBP1	-4776.0
OTUD7B	-4760.0
NEU1	-4754.0
EIF2B5	-4742.0
TSFM	-4733.0
NOP56	-4726.0
PGA4	-4725.0
LRRC41	-4721.0
PSMD2	-4715.0
CDC25A	-4711.0
PFDN6	-4704.0
DCAF5	-4684.0
NAGK	-4667.0
TUBB2A	-4666.0
B4GALT4	-4660.0
MRPL41	-4655.0
VCP	-4638.0
TPGS2	-4608.0
SLC17A5	-4597.0
HIC1	-4596.0
NUP62	-4588.0
PSMA1	-4587.0
COMMD9	-4561.0
MDC1	-4559.0
RPL14	-4555.0
MRPL27	-4538.0
UBA1	-4528.0
ASB1	-4515.0
TPR	-4504.0
WFS1	-4496.0
GOSR2	-4481.0
MRPL9	-4469.0
NR1H2	-4446.0
DYNC1H1	-4438.0
B4GALT3	-4430.0
RAB31	-4420.0
ARCN1	-4417.0
SEC24D	-4415.0
NOD1	-4398.0
MRPL45	-4373.0
PSMA5	-4364.0
CSNK2A2	-4363.0
ADORA2B	-4358.0
PSMD10	-4338.0
TF	-4330.0
SUMO3	-4323.0
SEC16A	-4307.0
EXOC3	-4304.0
MRPS11	-4302.0
MRPL28	-4300.0
MAN2A2	-4296.0
TNC	-4282.0
CBX2	-4279.0
PSMD1	-4278.0
RAB40A	-4258.0
KEAP1	-4234.0
GNA11	-4230.0
POMT1	-4224.0
MRPL20	-4223.0
ARSG	-4219.0
ST3GAL5	-4218.0
RAB27B	-4194.0
NUP214	-4176.0
RPS15A	-4165.0
DYNC1I2	-4164.0
MTIF2	-4162.0
RAB5C	-4159.0
DCTN3	-4136.0
USP22	-4121.0
MRPL49	-4100.0
TBCD	-4090.0
CCNF	-4079.0
PEX5	-4067.0
GALNT13	-4048.0
MRPL57	-4040.0
SKIV2L	-4037.0
GALNT2	-4034.0
RAB5B	-4030.0
DYNLL1	-4027.0
WDR20	-4019.0
PARK7	-4018.0
TUBA1C	-4017.0
MRPL4	-4016.0
EEF1B2	-4009.0
COPZ1	-4005.0
EID3	-4001.0
NCSTN	-3999.0
MRPL2	-3998.0
TUBB4B	-3995.0
EIF3K	-3994.0
STAMBP	-3988.0
CHCHD1	-3987.0
YY1	-3983.0
HSPA8	-3981.0
USP19	-3973.0
WDTC1	-3955.0
RPL27	-3935.0
METTL21A	-3929.0
WRAP53	-3916.0
BECN1	-3914.0
DHDDS	-3891.0
RAB24	-3879.0
TRIM4	-3870.0
CUL1	-3857.0
WDR61	-3852.0
EEF2KMT	-3839.0
GARS1	-3821.0
RAE1	-3807.0
BTRC	-3803.0
RPL35	-3792.0
NEURL2	-3777.0
COPB1	-3776.0
MRPL54	-3772.0
TGFB1	-3765.0
NANP	-3755.0
COG8	-3739.0
SNCA	-3734.0
SEC61B	-3730.0
CCT4	-3728.0
AR	-3719.0
RGS11	-3709.0
RPL39L	-3699.0
NUP88	-3689.0
CPE	-3683.0
GBF1	-3681.0
DPH1	-3678.0
POM121C	-3677.0
GSPT2	-3673.0
VAMP2	-3662.0
ASB18	-3661.0
RBX1	-3643.0
HERC2	-3620.0
RABGGTA	-3598.0
TAF10	-3596.0
PFDN5	-3592.0
RAB42	-3590.0
TRAPPC10	-3582.0
TRIM27	-3563.0
NSMCE4A	-3562.0
MRPS15	-3557.0
RPL39	-3539.0
KLHL25	-3516.0
ARFGAP3	-3514.0
PSMC4	-3510.0
LAMB1	-3507.0
ICMT	-3505.0
FUOM	-3497.0
PEX14	-3488.0
LTF	-3487.0
RRAGA	-3479.0
ALG2	-3461.0
NSMCE2	-3448.0
NUP98	-3400.0
LY6K	-3378.0
MGAT2	-3375.0
OTOA	-3356.0
FBXL19	-3345.0
EIF4A1	-3326.0
ARSB	-3324.0
AMFR	-3318.0
PIGS	-3315.0
COG7	-3309.0
NUB1	-3303.0
EIF2S2	-3286.0
COG4	-3282.0
RNF5	-3276.0
KARS1	-3275.0
MRPL21	-3274.0
RPS9	-3253.0
PDIA3	-3234.0
DCAF7	-3228.0
IGFBP4	-3223.0
GNG7	-3213.0
MRPL14	-3203.0
PARP1	-3200.0
PSMB2	-3187.0
MGAT5	-3183.0
NUP93	-3163.0
THRB	-3158.0
PNPLA2	-3157.0
MUL1	-3145.0
MRPS5	-3139.0
RPS24	-3138.0
EIF3M	-3135.0
HCFC1	-3126.0
MRPL46	-3113.0
TP53	-3110.0
RNF7	-3103.0
USP24	-3098.0
RPS29	-3082.0
SRP72	-3081.0
EEF1G	-3076.0
MRPL32	-3073.0
RIPK2	-3054.0
ST3GAL3	-3046.0
RGS6	-3031.0
RELA	-3015.0
UBE2R2	-2999.0
EIF4G1	-2994.0
EIF5A	-2971.0
ST6GAL1	-2961.0
NUP43	-2946.0
OTUD7A	-2919.0
ALG5	-2915.0
LMAN2L	-2910.0
FUCA2	-2892.0
HLA-A	-2891.0
IKBKE	-2890.0
FBXO2	-2887.0
RHOA	-2880.0
MSRB2	-2872.0
ADAMTSL5	-2858.0
TMEM132A	-2856.0
USP21	-2846.0
ESR1	-2842.0
IGFBP5	-2839.0
MRPL37	-2829.0
UBB	-2810.0
TGOLN2	-2798.0
NAPA	-2751.0
OBSL1	-2735.0
TRAF2	-2715.0
TCF7L2	-2708.0
ADAMTS12	-2706.0
PHC2	-2703.0
RAB20	-2702.0
MRPS7	-2694.0
CCDC8	-2692.0
MRPS22	-2680.0
APEH	-2675.0
QSOX1	-2658.0
ZNF350	-2644.0
DPAGT1	-2639.0
MRPS16	-2634.0
VASH1	-2614.0
RAB9A	-2612.0
UBE2M	-2611.0
UBC	-2608.0
CDC20	-2564.0
PSMD6	-2563.0
GNG2	-2555.0
MRPS18B	-2540.0
APOB	-2510.0
FN3K	-2509.0
PSMB5	-2492.0
ARRB2	-2487.0
PSENEN	-2481.0
USP7	-2472.0
SEC22A	-2458.0
PSMD13	-2447.0
MRPL16	-2436.0
MRPS24	-2434.0
SMC1A	-2433.0
FBXO21	-2423.0
CARS2	-2419.0
FOXK1	-2418.0
RCE1	-2354.0
GADD45GIP1	-2336.0
SPTA1	-2312.0
TSPAN14	-2290.0
INHA	-2287.0
UBE2F	-2268.0
HSP90B1	-2260.0
OTUD3	-2247.0
CPB1	-2227.0
MRPS33	-2194.0
TUBA8	-2159.0
YARS1	-2138.0
PIGV	-2123.0
SPSB2	-2121.0
MRPS36	-2108.0
THY1	-2092.0
FBXO7	-2079.0
DCTN6	-2064.0
RTN4RL1	-2062.0
RPS27A	-2058.0
SIAH2	-2051.0
PDIA6	-2048.0
RAB15	-2040.0
SMAD3	-1989.0
KLHL13	-1959.0
MRPL3	-1957.0
RAD18	-1947.0
DHPS	-1929.0
RNF144A	-1915.0
MRPL22	-1910.0
TRRAP	-1902.0
TP53BP1	-1895.0
CBX5	-1887.0
NARS1	-1872.0
DERL1	-1851.0
FCSK	-1831.0
RPL35A	-1829.0
PTP4A2	-1827.0
NCOA1	-1812.0
RAB38	-1805.0
ADAMTS6	-1799.0
SEC11C	-1765.0
MATN3	-1757.0
TMED10	-1755.0
KCTD6	-1724.0
PIGX	-1723.0
CALU	-1720.0
FBXO9	-1716.0
PPARA	-1702.0
PSME3	-1691.0
RAB8A	-1652.0
PIGF	-1637.0
N6AMT1	-1634.0
INCENP	-1590.0
RARA	-1588.0
RNF146	-1583.0
TPST2	-1578.0
XRN2	-1560.0
TGFBR2	-1532.0
MLEC	-1527.0
SRP14	-1521.0
SSR3	-1475.0
FBXO40	-1470.0
MRPL40	-1469.0
UBE2L6	-1460.0
GNE	-1426.0
USP30	-1419.0
PML	-1391.0
MRPS14	-1377.0
COPS4	-1359.0
EP300	-1330.0
NICN1	-1325.0
RAB40B	-1305.0
SMURF2	-1302.0
PSMC1	-1275.0
ADRA2C	-1270.0
MUC1	-1266.0
METTL22	-1235.0
UBE2L3	-1229.0
AURKAIP1	-1200.0
RPS4Y1	-1198.0
ZRANB1	-1194.0
NARS2	-1187.0
RAB1A	-1175.0
DCAF11	-1173.0
DCAF8	-1145.0
PCMT1	-1115.0
LARGE1	-1084.0
COPS3	-1083.0
COMMD3	-1082.0
ACTL6A	-1071.0
TTF1	-1065.0
FFAR4	-1060.0
HARS2	-1040.0
MRPL35	-1031.0
RAB3A	-1022.0
RAB7A	-1021.0
RAB29	-1011.0
CTNNB1	-1006.0
APOE	-966.0
UIMC1	-944.0
ST3GAL2	-942.0
GZMH	-938.0
UBE2H	-932.0
PREB	-921.0
PRKDC	-916.0
B3GLCT	-915.0
KIF13A	-913.0
OTUB2	-897.0
TUBA4A	-871.0
KLHL21	-866.0
SNCAIP	-861.0
TECTA	-852.0
OTULIN	-836.0
DYNLL2	-826.0
LEO1	-814.0
CCT2	-810.0
ATP6AP2	-800.0
STAT3	-775.0
TPST1	-761.0
MRPS27	-743.0
SEM1	-739.0
LMCD1	-729.0
PARS2	-726.0
THSD1	-724.0
RAB4B	-702.0
EARS2	-691.0
IARS1	-664.0
VWA1	-653.0
SEC24B	-641.0
PSME1	-634.0
USP9X	-627.0
LY6E	-623.0
CUL2	-617.0
RTF1	-605.0
USP48	-580.0
PSMA2	-550.0
RPS25	-545.0
KLHL20	-524.0
ENAM	-499.0
UCN	-496.0
EPRS1	-493.0
CCT8	-477.0
STAM	-473.0
TSPAN33	-466.0
SEC22B	-462.0
RAD52	-451.0
DCAF13	-448.0
SUMO2	-415.0
TTL	-404.0
MSRA	-389.0
UBE2G2	-386.0
RPL21	-383.0
ADRA2A	-365.0
SRD5A3	-364.0
SNX3	-357.0
PSMD11	-353.0
PSMB8	-350.0
ASB12	-348.0
MRRF	-342.0
KAT2A	-337.0
RPS3A	-334.0
PGM3	-331.0
TARS2	-330.0
RPS13	-295.0
MTIF3	-276.0
GFPT1	-256.0
MRPL12	-254.0
ADORA2A	-251.0
ADAMTS5	-249.0
FBXO10	-230.0
FBXL20	-212.0
SMAD2	-198.0
VASH2	-192.0
GHRL	-179.0
RPSA	-148.0
RARS1	-147.0
MBD6	-136.0
SVBP	-115.0
NUDT14	-111.0
H2AZ1	-107.0
HIF3A	-98.0
PCGF2	-82.0
EIF2S3	-66.0
MRPL52	-64.0
NUP155	-51.0
KLHL9	-48.0
ALG13	-46.0
RAB4A	-45.0
VDAC2	-31.0
NPM1	-27.0
POMGNT1	-24.0
LARS2	-17.0
KLHL42	-11.0
CNIH3	18.0
RAD23B	27.0
RAD23A	40.0
STC2	57.0
MRPS23	66.0
DPH5	71.0
SPRN	81.0
GLB1	88.0
NRIP1	143.0
ADAMTSL3	149.0
MIA3	162.0
MRPL15	169.0
MSRB3	185.0
RAB22A	211.0
WDR48	227.0
TXN	237.0
COMMD1	239.0
COPS5	254.0
MRPL51	255.0
TCP1	265.0
UBE2T	269.0
ARSD	272.0
WAC	291.0
GGCX	296.0
NUP42	299.0
LONP2	303.0
NRN1	306.0
FBXL4	311.0
RNF103	319.0
BTBD6	322.0
MRPL34	323.0
IGFBP7	330.0
USP10	334.0
DCTN4	354.0
SEC11A	395.0
ASB9	413.0
RNF168	439.0
NSF	470.0
TOMM20	474.0
EXOC4	475.0
MSRB1	484.0
USP3	492.0
WSB2	543.0
FBXL16	549.0
ST6GALNAC1	558.0
DNMT3B	567.0
HNRNPK	570.0
MRPL39	575.0
DAD1	591.0
TUBB2B	595.0
USP34	600.0
PSME4	609.0
TRAPPC9	624.0
HRC	626.0
UCHL3	628.0
THSD4	634.0
RAB9B	637.0
ASB14	646.0
ASB10	656.0
SKP1	657.0
EPAS1	697.0
IGF2	699.0
ADAMTS15	705.0
EDEM1	719.0
ANKRD9	723.0
RAB43	737.0
NEU3	745.0
BRCA1	754.0
FBXW11	758.0
RGS9	763.0
PAPPA2	767.0
MRPL48	773.0
STS	774.0
AP3M1	788.0
GCNT1	789.0
TADA2B	804.0
SPTB	806.0
NUP205	808.0
CCNA2	814.0
NEGR1	826.0
PPP6R3	842.0
MARS2	859.0
DCUN1D3	860.0
ADAMTS8	876.0
NFKB2	892.0
LEP	912.0
MRPS17	938.0
MRPL18	949.0
SENP8	951.0
ANKRD28	968.0
ASB7	995.0
ADAMTS3	1003.0
FARSB	1015.0
FBXW2	1027.0
ZNF131	1031.0
SSR1	1039.0
PTCD3	1050.0
DAG1	1118.0
USP13	1124.0
GMDS	1136.0
DOLPP1	1139.0
RAB6A	1159.0
AIMP1	1167.0
GALNT6	1172.0
FUT8	1194.0
RPS7	1197.0
COMMD7	1200.0
ETF1	1218.0
SEC23IP	1219.0
SLC30A5	1226.0
FBXO22	1248.0
RPS27L	1251.0
ANK1	1261.0
RPL22	1273.0
RHOT1	1276.0
RCN1	1284.0
CTR9	1295.0
RPL24	1297.0
EEF1A2	1298.0
MRPS18C	1328.0
EXOC1	1333.0
TULP4	1339.0
BST1	1355.0
MRPL47	1358.0
UBD	1371.0
NUP210	1376.0
THSD7B	1384.0
DERL2	1390.0
COG3	1412.0
IARS2	1417.0
DCAF6	1438.0
RAB6B	1445.0
MCFD2	1504.0
UGGT1	1525.0
COG5	1530.0
TAF9B	1536.0
MUC3A	1559.0
ELOC	1560.0
NUP153	1582.0
PSMA6	1616.0
DYNC1LI2	1641.0
NUP160	1654.0
TMED2	1655.0
APH1B	1671.0
CSNK2A1	1672.0
OGT	1675.0
PIGW	1680.0
B4GALT5	1683.0
DCAF17	1688.0
GNB3	1692.0
FBXO6	1696.0
ARF4	1701.0
HDAC1	1704.0
PSMA3	1706.0
NAE1	1725.0
SPHK1	1734.0
RNF123	1745.0
TUBB4A	1751.0
KLHL5	1757.0
TOP2A	1781.0
ST8SIA5	1794.0
KBTBD8	1808.0
RAB26	1814.0
PSMC6	1856.0
ALG10	1859.0
USP14	1909.0
NFKBIA	1910.0
CAND1	1929.0
ALG14	1954.0
UBA2	1992.0
HNRNPC	2019.0
SPTBN4	2040.0
CETN2	2050.0
RAB36	2061.0
MRPS30	2070.0
RNF139	2085.0
MRPS9	2089.0
PDCL	2094.0
GSPT1	2097.0
GOSR1	2105.0
CBX8	2109.0
NTNG2	2121.0
SCFD1	2127.0
TGFBR1	2130.0
SPTBN2	2135.0
UCHL1	2149.0
CCNE1	2155.0
PLAUR	2163.0
SRP19	2192.0
USP47	2193.0
MRPL13	2204.0
SIAH1	2213.0
TRIM25	2223.0
ARSJ	2234.0
USP42	2243.0
NGLY1	2264.0
COMMD2	2272.0
RAB3D	2276.0
DNMT3A	2286.0
FBXW12	2289.0
RABGGTB	2290.0
TOMM70	2306.0
ASGR2	2309.0
FBXO4	2318.0
MRPS25	2319.0
NUP54	2334.0
CAMKMT	2345.0
FPGT	2358.0
GNG5	2366.0
DCAF16	2368.0
NSMCE3	2372.0
PIAS1	2394.0
GNB5	2405.0
ST3GAL1	2406.0
APC	2414.0
APOL1	2416.0
VDAC1	2423.0
SAA1	2433.0
USP28	2439.0
SENP2	2446.0
AURKB	2450.0
CBX4	2465.0
UBE2E3	2468.0
CFTR	2470.0
IGF1	2480.0
MRPS31	2484.0
IGFBP2	2485.0
NAPSA	2505.0
ST3GAL6	2512.0
MAN1A1	2539.0
USP2	2546.0
USP44	2558.0
ASB8	2589.0
NUP35	2637.0
AIMP2	2640.0
RFT1	2645.0
NAPB	2662.0
AOPEP	2668.0
RAB37	2682.0
DCAF10	2727.0
COG2	2766.0
SENP5	2767.0
DARS1	2769.0
STAG1	2782.0
RAB2B	2795.0
TRAPPC4	2825.0
PPA1	2829.0
PIGH	2830.0
PHC1	2838.0
GNG12	2843.0
RWDD3	2870.0
EIF5	2871.0
B4GALT1	2878.0
FEM1A	2885.0
EXOC2	2908.0
TRAF6	2915.0
VHL	2927.0
CUL3	2930.0
CNTN3	2945.0
SMAD4	2951.0
CNIH1	2956.0
PIGN	2959.0
MRPS6	2968.0
TBCC	2969.0
HIPK2	2975.0
DYNC1I1	2990.0
RARS2	3011.0
NR1H3	3041.0
TOP2B	3067.0
CP	3083.0
SEC16B	3084.0
TGFA	3087.0
CASP8AP2	3118.0
CANX	3141.0
KBTBD13	3150.0
PSMD5	3165.0
ERO1A	3167.0
GFM2	3176.0
MTFMT	3212.0
SEC23A	3257.0
SLC30A6	3263.0
EIF5B	3268.0
PSME2	3291.0
SENP1	3296.0
MRPL44	3308.0
AGT	3348.0
CMAS	3380.0
MITF	3388.0
CUL4A	3409.0
FBXO11	3432.0
SEC24A	3440.0
SEC61A2	3459.0
MAT2B	3460.0
LSAMP	3476.0
UBE2D2	3489.0
HDAC2	3508.0
ASB11	3517.0
MRPL30	3540.0
ADAMTSL2	3557.0
COPS8	3577.0
LRRC49	3622.0
XRCC4	3628.0
CDC73	3684.0
BRCC3	3705.0
SMC3	3712.0
NOD2	3722.0
SATB1	3754.0
RPL3L	3763.0
MRPS35	3764.0
ARSK	3775.0
MRPS28	3787.0
AGBL1	3800.0
SSPOP	3810.0
DPH3	3811.0
FBXL22	3818.0
HDAC4	3822.0
UBE2S	3867.0
DARS2	3886.0
KLHL41	3898.0
CAPZA1	3900.0
ASB16	3906.0
C1GALT1C1	3911.0
PIGP	3936.0
USP33	3940.0
RAB18	3942.0
GALNT1	3945.0
SUDS3	3953.0
DNAJC3	3962.0
TNKS	3975.0
VDAC3	3977.0
EIF2S1	4031.0
PGR	4035.0
SRP9	4038.0
DCUN1D2	4043.0
GNGT2	4058.0
TFAP2C	4066.0
NPL	4073.0
PSMA4	4076.0
TUSC3	4094.0
TBCA	4107.0
SLC35A1	4115.0
SPCS1	4118.0
UBE2N	4119.0
DYNC1LI1	4123.0
NOP58	4137.0
GALNT14	4157.0
FBXO32	4158.0
PPARGC1A	4165.0
LRR1	4180.0
KBTBD6	4185.0
COL7A1	4190.0
MAP3K7	4197.0
UHRF2	4204.0
MBD5	4207.0
PPP6C	4218.0
SRP54	4227.0
RAB2A	4245.0
GALNT5	4257.0
PSMB9	4260.0
CCT6B	4261.0
ALG11	4266.0
SATB2	4308.0
CALB1	4309.0
UBXN7	4314.0
TOP1	4368.0
MRPS10	4381.0
PIGM	4390.0
EIF3E	4397.0
F5	4416.0
SEMA5B	4419.0
PEX2	4438.0
SEC61G	4453.0
PRMT3	4464.0
PRSS23	4475.0
GALNT18	4493.0
EIF4A2	4494.0
FBXL3	4542.0
SPCS2	4543.0
TRAM1	4548.0
PSMD12	4558.0
RAB14	4562.0
SUMO1	4613.0
KDM1B	4615.0
MARCHF6	4616.0
EIF3J	4622.0
H2BC5	4656.0
TUBB1	4665.0
RAB11A	4666.0
HLTF	4669.0
NDC1	4688.0
GFM1	4689.0
CCNE2	4691.0
RBBP5	4693.0
ETFBKMT	4713.0
RAD21	4730.0
NUP133	4739.0
ASB5	4744.0
USP25	4748.0
UBE2E1	4757.0
B3GALNT2	4763.0
DDX17	4766.0
SPARCL1	4810.0
BET1	4829.0
PUM2	4831.0
EIF1AX	4832.0
TRIM13	4841.0
P2RY2	4855.0
SHPRH	4870.0
USP16	4881.0
GATA6	4882.0
DNAJC24	4905.0
MDM4	4928.0
RNF128	4929.0
NUP107	4939.0
NUS1	4959.0
SMAD1	4961.0
C1GALT1	5025.0
UBE2Q2	5040.0
USP8	5048.0
TSPAN5	5059.0
MRPL33	5081.0
RANBP2	5097.0
ALG9	5106.0
FEM1B	5110.0
TOPORS	5114.0
FBXL13	5124.0
MME	5125.0
BMI1	5138.0
ACTR10	5159.0
ITM2B	5197.0
DCUN1D5	5202.0
UBE2A	5212.0
SAR1B	5213.0
DPH6	5216.0
MAN2A1	5224.0
RAB10	5228.0
FBXW7	5253.0
ST8SIA1	5271.0
PLA2G7	5272.0
CALM1	5275.0
TTLL10	5291.0
PLG	5294.0
WARS1	5297.0
TRAPPC6B	5307.0
BIRC2	5312.0
MDM2	5328.0
GAN	5342.0
PEX12	5343.0
MYRIP	5352.0
SP100	5380.0
UBE2K	5387.0
PEX13	5421.0
RNF2	5423.0
EIF4E	5439.0
ALG8	5449.0
TRAPPC2	5463.0
PPA2	5481.0
FBXL5	5493.0
MAN1A2	5512.0
EXOC6	5521.0
ACHE	5540.0
KIN	5572.0
DDX58	5591.0
STX17	5615.0
UBE2V2	5620.0
CCDC59	5646.0
MRPL1	5656.0
GNG10	5674.0
MRPL50	5689.0
LMAN1	5694.0
ART4	5704.0
COMMD10	5706.0
CD109	5723.0
NUP37	5735.0
ATXN3	5741.0
NR3C1	5752.0
PTEN	5760.0
UGGT2	5762.0
VCPIP1	5769.0
BTBD1	5774.0
EEF1E1	5800.0
NUP50	5855.0
RAB30	5879.0
B3GNT5	5886.0
VDR	5889.0
MRPL19	5890.0
ASB4	5901.0
THSD7A	5903.0
ASB3	5912.0
DCUN1D4	5916.0
PIGK	5922.0
KLHL2	5933.0
F8	5952.0
SLC30A7	5982.0
CD59	6007.0
BARD1	6030.0
CYLD	6032.0
SPTBN5	6048.0
KLHL3	6051.0
INHBA	6052.0
WRN	6061.0
EIF5A2	6072.0
SEH1L	6077.0
PHC3	6083.0
INO80C	6098.0
MYSM1	6124.0
MANEA	6140.0
VBP1	6143.0
UBE2D3	6151.0
WSB1	6160.0
NAPG	6186.0
PCSK2	6189.0
ASB2	6191.0
SPP1	6209.0
PGAP1	6241.0
AGBL3	6253.0
LARS1	6265.0
USP49	6278.0
PROS1	6289.0
AURKA	6301.0
PAPPA	6316.0
RAB33B	6319.0
RAB12	6337.0
USP12	6354.0
DPM1	6362.0
TNKS2	6363.0
BIRC5	6367.0
RPL9	6370.0
SMC5	6387.0
USO1	6395.0
ADRB2	6428.0
ZDHHC2	6456.0
STAM2	6459.0
B3GNT2	6463.0
MIA2	6490.0
TTLL9	6501.0
AGBL2	6502.0
TTLL7	6512.0
H2BC4	6513.0
DDX5	6525.0
EXOC5	6534.0
VCPKMT	6540.0
GNA14	6546.0
UBE2G1	6551.0
KIF5B	6552.0
H3-3A	6579.0
PIGB	6586.0
RPL22L1	6595.0
RAB5A	6603.0
SEL1L	6611.0
COMMD8	6617.0
ART3	6640.0
KTN1	6655.0
CSF2RB	6665.0
GATA3	6671.0
ERCC8	6685.0
PIAS2	6688.0
SMC6	6710.0
RAB3C	6723.0
EDEM3	6726.0
NOTUM	6727.0
UBE2D1	6734.0
ST6GALNAC2	6754.0
SERPINA10	6761.0
NLRP3	6794.0
RPL36A	6879.0
CHM	6885.0
SOCS6	6907.0
ARFGEF2	6908.0
MTRF1L	6924.0
UBA6	6954.0
CAPZA2	6977.0
UBA3	6997.0
SKP2	7003.0
SP3	7005.0
AGTPBP1	7014.0
COPS2	7016.0
STAG2	7024.0
ENPEP	7060.0
INO80D	7067.0
RAB19	7073.0
YOD1	7102.0
CES1	7111.0
NR3C2	7119.0
SOCS5	7176.0
UCHL5	7193.0
TBCE	7215.0
IFIH1	7223.0
MRPL42	7230.0
ANK3	7258.0
COG6	7273.0
NR2C1	7275.0
SOCS2	7323.0
ASXL2	7374.0
ASB15	7396.0
TMED7	7411.0
HLA-B	7431.0
ADAMTS9	7443.0
CNTN4	7465.0
ATXN7	7493.0
NR5A2	7499.0
LYPD5	7505.0
IDE	7537.0
PFDN4	7559.0
KLHL11	7563.0
VNN1	7572.0
BGLAP	7578.0
CRHR2	7581.0
MAGT1	7627.0
THBS1	7643.0
IL33	7666.0
CCP110	7689.0
ERO1B	7691.0
SBSPON	7693.0
TDG	7694.0
BLM	7698.0
TUBB3	7756.0
ADAM10	7778.0
MT-RNR1	7788.0
ASGR1	7803.0
USP37	7806.0
CUL4B	7811.0
EXOC8	7815.0
RAB21	7819.0
GALNT7	7822.0
ALPL	7823.0
BCL10	7831.0
LMO7	7850.0
UBE2B	7887.0
B2M	7903.0
SUZ12	7927.0
CLSPN	7947.0
CD52	7954.0
KBTBD7	7979.0
GPLD1	7980.0
SPCS3	8030.0
GALNT4	8076.0
ST6GALNAC3	8094.0
FBXO30	8103.0
GNG11	8107.0
B4GALT6	8123.0
CDK1	8200.0
POLB	8214.0
ALG6	8225.0
LYZ	8268.0
KLF4	8280.0
H2AC18	8329.0
RAB8B	8371.0
SERPINA1	8375.0
HIF1A	8395.0
CHML	8415.0
UBE2W	8416.0
ALG10B	8432.0
GNAQ	8465.0
PIGA	8517.0
GNB4	8519.0
NCOA2	8533.0
KAT2B	8536.0
ACE2	8539.0
ST8SIA6	8543.0
USP15	8559.0
BCHE	8567.0
POMK	8610.0
BIRC3	8623.0
RAB27A	8670.0
SEMA5A	8696.0
ST8SIA4	8708.0
MGAT4A	8724.0
DCUN1D1	8735.0
NTNG1	8739.0
ADGRF5	8777.0
NUP58	8794.0
EVA1A	8814.0
FEM1C	8843.0
H2BC21	8851.0
FGF23	8908.0
RNF152	8910.0
MGAT4C	8924.0
RORA	8950.0
KIF5C	8952.0
H2AC6	8988.0
TNFAIP3	9059.0
GCNT4	9116.0
FCGR3B	9117.0
CUL5	9127.0
VNN3	9139.0
MYC	9159.0
GALNT3	9192.0
SOCS3	9198.0
RAB3B	9202.0
MT-RNR2	9249.0
GRIA1	9317.0
ADAMTS18	9324.0
FBXO15	9352.0
SORL1	9394.0
AREG	9397.0
ADAMTS1	9426.0
NR4A2	9439.0
IL6	9444.0
ADAMTS4	9450.0
VNN2	9461.0

---

Infectious disease

Infectious disease

	554
set	Infectious disease
setSize	772
pANOVA	8.98e-17
s.dist	-0.176
p.adjustANOVA	7.26e-15

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
SLC25A6	-9520
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
VAMP1	-9324
GTF2F1	-9321
IGLV2-8	-9316
H2BC12	-9313
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
SLC25A6	-9520
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
VAMP1	-9324
GTF2F1	-9321
IGLV2-8	-9316
H2BC12	-9313
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
NT5E	-9206
GPBAR1	-9186
PTHLH	-9182
H2AW	-9173
FXYD2	-9172
RPS4X	-9157
CTSG	-9144
PTH2R	-9125
IGLC2	-9098
IGHV3-11	-9041
FXYD6	-9023
IGHG2	-9010
AAAS	-9006
AP1M1	-8972
AP2A2	-8966
IGHV3-30	-8906
SRC	-8900
SSRP1	-8890
STX1B	-8864
SIGMAR1	-8836
IGHG3	-8775
SNF8	-8773
ABL1	-8744
RPLP2	-8715
IGLV1-47	-8713
IGLV3-21	-8651
CHMP2A	-8605
PRKCSH	-8602
MOGS	-8596
GTF2E2	-8588
VEGFA	-8586
CD4	-8579
COMT	-8571
RPL3	-8564
IGKV3-15	-8522
DVL2	-8480
SEC13	-8457
NELFB	-8452
ACTG1	-8451
IGHG4	-8417
STX1A	-8416
RPL23	-8406
IGKV3-20	-8400
SH3GL1	-8287
HGS	-8283
C3AR1	-8279
RPS14	-8278
RPS12	-8256
ADCY6	-8246
ANTXR1	-8240
SUPT16H	-8220
RPL36	-8166
CTDP1	-8161
CHD3	-8140
RPL19	-8133
RPS28	-8128
IGLV2-23	-8106
ADCY7	-8082
ST3GAL4	-8065
RPL28	-8031
CD163	-8028
EEF2	-8011
IGLV3-19	-7984
PTH1R	-7949
MTA1	-7942
RPL37	-7930
RPS26	-7908
CTSL	-7889
FYN	-7874
NELFE	-7873
RPL31	-7842
BAIAP2	-7819
PARP6	-7777
PDCD1	-7767
HDAC3	-7742
TLR9	-7728
RPL26L1	-7694
NUP188	-7684
POLR2G	-7651
UBA52	-7643
DAXX	-7642
RPS5	-7633
NCKIPSD	-7618
PSMA7	-7617
TAF15	-7616
PSMB7	-7580
CHMP4A	-7578
PSMC3	-7538
TUBB	-7529
GNB2	-7507
SUPT5H	-7505
UBE2I	-7499
WASF1	-7486
RPL13	-7472
RPS18	-7468
IGHV4-59	-7466
POLR2F	-7453
VPS25	-7451
RPL7A	-7394
RPS16	-7390
NELFA	-7389
TRIM28	-7371
VPS28	-7361
RPS10	-7354
NUP85	-7351
RPL26	-7340
AP2A1	-7331
WASF2	-7299
ARF1	-7273
RPL10A	-7253
RPN1	-7232
RPL30	-7217
AP2M1	-7207
ACTB	-7187
GANAB	-7181
SCTR	-7153
ARPC1A	-7142
RPS11	-7138
PSMD4	-7134
RPL4	-7127
FAU	-7067
AP1B1	-7052
RPL13A	-7019
IGKV2-30	-7018
MYO9B	-6996
POLR2H	-6957
GNAI2	-6950
PSMC5	-6942
MTA3	-6916
RPS17	-6903
GTF2H4	-6879
ARPC1B	-6869
CALR	-6854
CDK9	-6851
GNB1	-6844
IGKV4-1	-6785
RPS15	-6758
GPS2	-6743
DVL3	-6742
RPL29	-6731
PSMD8	-6703
CHMP1A	-6691
RPL36AL	-6668
BRK1	-6636
IGLV6-57	-6578
GNAS	-6561
RPS20	-6537
RPL38	-6495
EDEM2	-6490
RPL12	-6483
PSMB4	-6417
MYO1C	-6410
RPLP0	-6397
RPL10	-6333
MGAT4B	-6306
RANBP1	-6303
RPL8	-6300
ADCY3	-6292
ISG15	-6233
POM121	-6225
RPL5	-6221
VPS33B	-6196
RPL37A	-6135
MC1R	-6117
EGFR	-6115
RPL27A	-6113
DOCK1	-6096
CHMP4B	-6078
DDOST	-6043
NMT1	-6029
C3	-5996
IGLV1-40	-5992
MAPK3	-5987
ITPR3	-5979
NCOR2	-5973
RPS2	-5959
RPS8	-5958
P2RX4	-5904
RPS21	-5899
IMPDH2	-5882
GSK3A	-5880
PARP16	-5876
RPL11	-5867
RPS27	-5866
MAN1B1	-5852
RPLP1	-5846
RPS6	-5819
DUSP16	-5770
PSMD9	-5765
IGHV4-39	-5760
RPL17	-5749
RPL15	-5698
IGKV2D-28	-5697
HMG20B	-5680
VPS4A	-5655
RPL32	-5598
AP2B1	-5595
MGAT1	-5591
RPN2	-5586
HSP90AB1	-5567
PYCARD	-5560
AP2S1	-5530
IGHV1-2	-5528
BRMS1	-5517
PSMF1	-5494
POMC	-5478
RANGAP1	-5460
XRCC6	-5440
IFNGR2	-5433
RBBP7	-5415
RPL41	-5397
RCC1	-5394
IMPDH1	-5362
RPL18	-5360
PSMB3	-5327
CHD4	-5297
PABPN1	-5294
ELOB	-5284
IGHG1	-5275
MBD3	-5274
IGLV1-51	-5257
CHMP3	-5253
RPL23A	-5246
RNMT	-5242
PSMD3	-5235
FZD7	-5230
AP1S1	-5221
STT3A	-5213
IGKC	-5210
KPNA2	-5200
ARPC2	-5195
PSMB1	-5182
RPL34	-5148
UVRAG	-5130
PARP10	-5128
TYK2	-5124
SUPT4H1	-5123
FURIN	-5091
ST6GALNAC4	-5073
PSMD7	-5070
GPR20	-5058
RPL7	-5057
CLTA	-5023
MAP2K7	-5020
RIPK1	-5016
RPL18A	-5015
CHMP6	-4996
PSMD14	-4951
PSMB10	-4948
RPL6	-4942
RPS23	-4940
MYO5A	-4904
RAN	-4882
PSMC2	-4880
PSMB6	-4849
RPS19	-4848
GATAD2A	-4846
RPS3	-4842
POLR2I	-4811
POLR2C	-4802
HMOX1	-4801
MRC1	-4738
PSMD2	-4715
CYSLTR2	-4710
PACS1	-4639
VCP	-4638
ANTXR2	-4636
IGKV1D-39	-4621
NUP62	-4588
PSMA1	-4587
ERCC3	-4568
MVB12B	-4567
MAP2K2	-4556
RPL14	-4555
TPR	-4504
IGKV1-12	-4498
DYNC1H1	-4438
POLR2E	-4389
PSMA5	-4364
ADORA2B	-4358
IPO5	-4347
PSMD10	-4338
TAF6	-4292
PSMD1	-4278
KEAP1	-4234
TAF9	-4231
NUP214	-4176
RPS15A	-4165
DYNC1I2	-4164
DBP	-4134
IL18	-4093
WASF3	-4071
DYNLL1	-4027
RAMP2	-3984
VAV1	-3953
ELOA	-3947
RPL27	-3935
BECN1	-3914
ARPC4	-3888
PARP4	-3881
RAE1	-3807
BTRC	-3803
RPL35	-3792
PSTPIP1	-3791
TGFB1	-3765
PRMT1	-3758
RPL39L	-3699
NUP88	-3689
POM121C	-3677
VAMP2	-3662
VPS37C	-3658
BTK	-3657
IGHV4-34	-3644
RBX1	-3643
FXYD1	-3636
FEN1	-3621
GLP2R	-3617
PPIA	-3610
ATP1A1	-3606
TAF10	-3596
TRIM27	-3563
AVPR2	-3554
TXNIP	-3546
RPL39	-3539
NFKB1	-3526
PSMC4	-3510
DOCK2	-3489
LTF	-3487
SLC25A5	-3474
PHF21A	-3462
MTA2	-3401
NUP98	-3400
MGAT2	-3375
MVB12A	-3360
POLR2J	-3355
PLCG1	-3308
NCKAP1L	-3307
CPSF4	-3300
RPS9	-3253
NELFCD	-3248
BRD4	-3231
SH3KBP1	-3219
GNG7	-3213
PARP1	-3200
PSMB2	-3187
CLTC	-3186
MGAT5	-3183
NCOR1	-3170
RHBDF2	-3167
NUP93	-3163
CHMP7	-3149
RPS24	-3138
CYFIP1	-3125
DRD1	-3120
RPS29	-3082
ST3GAL3	-3046
FNTB	-3027
VPS37D	-3017
RELA	-3015
ST6GAL1	-2961
NUP43	-2946
KDM1A	-2926
ADCY5	-2906
DVL1	-2895
HLA-A	-2891
UBB	-2810
RAC1	-2805
GGT1	-2784
HSP90AA1	-2745
UBC	-2608
ENO1	-2605
PSMD6	-2563
GNG2	-2555
KPNB1	-2542
PSMB5	-2492
ERCC2	-2482
ELMO2	-2473
PSMD13	-2447
POLR2L	-2358
GGT5	-2348
HMGA1	-2228
RPS27A	-2058
GNAI1	-2057
GTF2F2	-2047
CYBA	-1998
PRKACA	-1995
SAP18	-1972
MAP2K3	-1950
NEDD4L	-1891
ELK1	-1858
LCK	-1841
RPL35A	-1829
MNAT1	-1809
MYH2	-1794
APOBEC3G	-1749
TBL1X	-1706
PSME3	-1691
SV2A	-1676
AHCYL1	-1655
VAV2	-1647
TSG101	-1644
DUT	-1640
CBX1	-1599
POLR2D	-1531
ADCY9	-1529
GSDMD	-1439
PRKAR2B	-1412
NMT2	-1397
PML	-1391
ELL	-1355
GPR176	-1349
FKBP4	-1306
SAP30L	-1293
IGLV1-44	-1280
PSMC1	-1275
POLR2A	-1215
SYK	-1210
TAF4	-1203
RPS4Y1	-1198
VIPR1	-1174
SLC25A4	-1070
GPR39	-1035
RAB7A	-1021
ATP1A2	-1013
CTNNB1	-1006
PTK2	-965
ST3GAL2	-942
MYH9	-899
ATP6V1H	-876
CRK	-859
DYNLL2	-826
EZH2	-801
SEM1	-739
LIG1	-725
P2RY11	-710
GRB2	-640
PSME1	-634
IGHV3-48	-616
IGKV1-16	-593
ELMO1	-573
WIPF3	-570
PSMA2	-550
RPS25	-545
CCNK	-540
STAM	-473
ADRB1	-453
RPL21	-383
POLR2B	-362
PSMD11	-353
PSMB8	-350
RPS3A	-334
MAP1LC3B	-329
RCOR1	-319
PTGER2	-310
NCK1	-304
RPS13	-295
GTF2E1	-282
ADORA2A	-251
GTF2H2	-233
RPSA	-148
NUP155	-51
NPM1	-27
JAK1	-26
ADRB3	43
TBP	58
UBAP1	138
HCK	150
RNF213	223
TXN	237
TCEA1	285
NUP42	299
ADCY2	328
PIK3R4	371
PTGDR	429
CD9	437
BANF1	440
VTA1	485
FNTA	525
HNRNPK	570
ADCYAP1	578
MAPK1	583
VIPR2	584
DAD1	591
PSME4	609
IL10	616
TAF1	629
SKP1	657
IGHV3-23	658
TAF2	703
GNAI3	727
GATAD2B	739
NUP205	808
KPNA4	834
WIPF2	869
NFKB2	892
VPS4B	1107
STAT2	1146
FUT8	1194
RPS7	1197
RAMP3	1215
CBLL1	1245
RPS27L	1251
CCR5	1259
RPL22	1273
MAP2K1	1296
RPL24	1297
IFNGR1	1319
NUP210	1376
ADCYAP1R1	1464
XRCC5	1475
TAF9B	1536
ITGB1	1539
ELOC	1560
NUP153	1582
NCBP2	1609
PDZD3	1615
PSMA6	1616
DYNC1LI2	1641
NUP160	1654
GNB3	1692
HDAC1	1704
PSMA3	1706
AVP	1752
TAF3	1753
FKBP1A	1764
RBBP4	1776
ADM	1777
CSNK1A1	1813
MAP2K4	1833
PSMC6	1856
SFPQ	1882
ARPC3	1908
P2RX7	1938
SYT2	2020
CDK7	2033
NFE2L2	2107
DPEP2	2161
IFNAR1	2188
FCGR2A	2194
TAF4B	2228
PRKX	2291
TAF7	2320
NUP54	2334
CYFIP2	2361
GNG5	2366
GTF2A2	2369
MAPK14	2383
TXNRD1	2385
EED	2399
GNB5	2405
ST3GAL1	2406
CORO1A	2417
GTF2H1	2425
ADCY1	2469
SV2B	2495
CRBN	2541
CHMP5	2563
HSPA1A	2615
NUP35	2637
VPS37A	2717
ADCY4	2789
GTF2H5	2842
GNG12	2843
CDC42	2858
RAMP1	2880
VHL	2927
CUL3	2930
NCKAP1	2931
IRS1	2964
DYNC1I1	2990
TAF11	3077
ATP1B2	3109
SRPK2	3115
CANX	3141
PSMD5	3165
PIK3C3	3169
WAS	3173
CCNH	3223
ADAM17	3261
POLR2K	3276
PSME2	3291
NCBP1	3300
ATP1B3	3330
CD247	3342
ENTPD5	3398
PDCD6IP	3442
HDAC2	3508
TAF12	3521
SUGT1	3539
PRKAR1B	3558
PRKACB	3604
CHMP4C	3607
VPS36	3620
XRCC4	3628
GNAZ	3694
ZCRB1	3737
RPL3L	3763
FXYD7	3783
IGKV1-33	3826
ABI1	3864
ITPR1	3869
PTGIR	3894
GALNT1	3945
IL1R1	3952
SUDS3	3953
DNAJC3	3962
ROCK2	3994
HRH2	3995
MYO10	4030
GTF2H3	4041
IL6R	4042
SCT	4051
GNGT2	4058
PSMA4	4076
TUSC3	4094
DYNC1LI1	4123
PSMB9	4260
GPR27	4289
ENTPD1	4333
GTF2B	4364
TAF5	4377
LHCGR	4422
ZBP1	4433
NOXA1	4495
CD8B	4510
AP1G1	4550
PSMD12	4558
FGR	4585
SUMO1	4613
ATP1A4	4636
PRKAR2A	4641
H2BC5	4656
ARPC5	4663
NDC1	4688
MAPK8	4720
NUP133	4739
VAV3	4780
PGK1	4836
LIG4	4840
ABI2	4856
CBL	4864
ACTR3	4876
VPS37B	4937
NUP107	4939
RNGTT	4943
GRSF1	4944
WIPF1	4978
CTNND1	5064
RANBP2	5097
WNT5A	5108
PLCG2	5152
CD28	5157
MAN2A1	5224
PAK2	5269
CALM1	5275
MAP2K6	5310
ACTR2	5314
TBL1XR1	5336
S1PR1	5621
GNG10	5674
CREB1	5680
NUP37	5735
PTGES3	5736
NR3C1	5752
KPNA1	5759
ROCK1	5817
NUP50	5855
PRKAR1A	5856
ATP1B1	5857
CHMP2B	5877
VIP	5910
REST	5971
SEH1L	6077
ITPR2	6099
WASL	6108
CCNT2	6121
ARID4B	6174
JAK3	6200
GIPR	6230
EIF2AK2	6233
PARP8	6264
NOS2	6271
RPL9	6370
FCGR3A	6371
ADRB2	6428
GSK3B	6450
STAM2	6459
KPNA3	6465
H2BC4	6513
DDX5	6525
RPL22L1	6595
RAB5A	6603
IFNAR2	6667
EPS15	6673
ST6GALNAC2	6754
NLRP3	6794
CEBPD	6830
RPL36A	6879
AP1S2	7001
TLR7	7011
PSIP1	7030
PARP14	7049
CYSLTR1	7068
CASP1	7103
SYT1	7118
ARID4A	7233
XPO1	7330
CD3G	7496
CRHR2	7581
GTF2A1	7584
TAF13	7602
MAGT1	7627
TBK1	7671
PARP9	7678
CDH1	7696
YES1	7797
SAP30	7866
B2M	7903
SRPK1	7919
SUZ12	7927
MEFV	8037
MET	8067
ST6GALNAC3	8094
GNG11	8107
LYN	8170
CCNT1	8260
CALCRL	8275
JAK2	8287
H2AC18	8329
RB1	8392
CXCR4	8427
GNB4	8519
AP1S3	8535
ACE2	8539
PLK2	8574
MGAT4A	8724
KPNA5	8768
TSHR	8770
ITGA4	8771
NUP58	8794
H2BC21	8851
MGAT4C	8924
TLR2	8970
H2AC6	8988
HBEGF	9018
JUN	9070
CUL5	9127
PTGER4	9214
FCGR1A	9248
IL1B	9408
IL6	9444

---

GTP hydrolysis and joining of the 60S ribosomal subunit

GTP hydrolysis and joining of the 60S ribosomal subunit

	462
set	GTP hydrolysis and joining of the 60S ribosomal subunit
setSize	111
pANOVA	1.43e-16
s.dist	-0.454
p.adjustANOVA	1.1e-14

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS4X	-9157
RPLP2	-8715
EIF3F	-8575
RPL3	-8564
RPL23	-8406
EIF3D	-8286
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
EIF3L	-7612
EIF4H	-7534

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS4X	-9157
RPLP2	-8715
EIF3F	-8575
RPL3	-8564
RPL23	-8406
EIF3D	-8286
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
EIF3L	-7612
EIF4H	-7534
RPL13	-7472
RPS18	-7468
RPL7A	-7394
RPS16	-7390
RPS10	-7354
RPL26	-7340
RPL10A	-7253
RPL30	-7217
RPS11	-7138
RPL4	-7127
FAU	-7067
RPL13A	-7019
EIF3C	-7000
EIF3B	-6904
RPS17	-6903
EIF3A	-6833
RPS15	-6758
RPL29	-6731
RPL36AL	-6668
EIF3H	-6622
RPS20	-6537
RPL38	-6495
RPL12	-6483
RPLP0	-6397
RPL10	-6333
RPL8	-6300
RPL5	-6221
EIF3G	-6151
RPL37A	-6135
RPL27A	-6113
RPS2	-5959
RPS8	-5958
EIF3I	-5930
RPS21	-5899
RPL11	-5867
RPS27	-5866
RPLP1	-5846
RPS6	-5819
RPL17	-5749
EIF4B	-5716
RPL15	-5698
RPL32	-5598
RPL41	-5397
RPL18	-5360
RPL23A	-5246
RPL34	-5148
RPL7	-5057
RPL18A	-5015
RPL6	-4942
RPS23	-4940
RPS19	-4848
RPS3	-4842
RPL14	-4555
RPS15A	-4165
EIF3K	-3994
RPL27	-3935
RPL35	-3792
RPL39L	-3699
RPL39	-3539
EIF4A1	-3326
EIF2S2	-3286
RPS9	-3253
RPS24	-3138
EIF3M	-3135
RPS29	-3082
EIF4G1	-2994
RPS27A	-2058
RPL35A	-1829
RPS4Y1	-1198
RPS25	-545
RPL21	-383
RPS3A	-334
RPS13	-295
RPSA	-148
EIF2S3	-66
RPS7	1197
RPS27L	1251
RPL22	1273
RPL24	1297
EIF5	2871
EIF5B	3268
RPL3L	3763
EIF2S1	4031
EIF3E	4397
EIF4A2	4494
EIF3J	4622
EIF1AX	4832
EIF4E	5439
RPL9	6370
RPL22L1	6595
RPL36A	6879

---

Eukaryotic Translation Termination

Eukaryotic Translation Termination

	373
set	Eukaryotic Translation Termination
setSize	92
pANOVA	3.27e-16
s.dist	-0.492
p.adjustANOVA	2.38e-14

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS4X	-9157
RPLP2	-8715
RPL3	-8564
RPL23	-8406
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
RPL13	-7472
RPS18	-7468
RPL7A	-7394
RPS16	-7390

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS4X	-9157
RPLP2	-8715
RPL3	-8564
RPL23	-8406
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
RPL13	-7472
RPS18	-7468
RPL7A	-7394
RPS16	-7390
RPS10	-7354
RPL26	-7340
RPL10A	-7253
RPL30	-7217
RPS11	-7138
RPL4	-7127
FAU	-7067
RPL13A	-7019
RPS17	-6903
RPS15	-6758
RPL29	-6731
TRMT112	-6708
RPL36AL	-6668
RPS20	-6537
RPL38	-6495
RPL12	-6483
RPLP0	-6397
RPL10	-6333
RPL8	-6300
RPL5	-6221
RPL37A	-6135
RPL27A	-6113
RPS2	-5959
RPS8	-5958
RPS21	-5899
RPL11	-5867
RPS27	-5866
RPLP1	-5846
RPS6	-5819
RPL17	-5749
RPL15	-5698
RPL32	-5598
RPL41	-5397
RPL18	-5360
RPL23A	-5246
RPL34	-5148
RPL7	-5057
RPL18A	-5015
RPL6	-4942
RPS23	-4940
RPS19	-4848
RPS3	-4842
RPL14	-4555
RPS15A	-4165
RPL27	-3935
RPL35	-3792
RPL39L	-3699
GSPT2	-3673
RPL39	-3539
RPS9	-3253
RPS24	-3138
RPS29	-3082
APEH	-2675
RPS27A	-2058
RPL35A	-1829
N6AMT1	-1634
RPS4Y1	-1198
RPS25	-545
RPL21	-383
RPS3A	-334
RPS13	-295
RPSA	-148
RPS7	1197
ETF1	1218
RPS27L	1251
RPL22	1273
RPL24	1297
GSPT1	2097
RPL3L	3763
RPL9	6370
RPL22L1	6595
RPL36A	6879

---

Selenocysteine synthesis

Selenocysteine synthesis

	1128
set	Selenocysteine synthesis
setSize	92
pANOVA	3.84e-16
s.dist	-0.491
p.adjustANOVA	2.62e-14

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS4X	-9157
RPLP2	-8715
RPL3	-8564
RPL23	-8406
RPS14	-8278
RPS12	-8256
EEFSEC	-8185
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
SARS1	-7485
RPL13	-7472
RPS18	-7468

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS4X	-9157
RPLP2	-8715
RPL3	-8564
RPL23	-8406
RPS14	-8278
RPS12	-8256
EEFSEC	-8185
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
SARS1	-7485
RPL13	-7472
RPS18	-7468
RPL7A	-7394
RPS16	-7390
RPS10	-7354
RPL26	-7340
RPL10A	-7253
RPL30	-7217
RPS11	-7138
RPL4	-7127
FAU	-7067
RPL13A	-7019
RPS17	-6903
RPS15	-6758
RPL29	-6731
RPL36AL	-6668
RPS20	-6537
RPL38	-6495
RPL12	-6483
RPLP0	-6397
RPL10	-6333
RPL8	-6300
RPL5	-6221
RPL37A	-6135
RPL27A	-6113
RPS2	-5959
RPS8	-5958
RPS21	-5899
RPL11	-5867
RPS27	-5866
RPLP1	-5846
RPS6	-5819
RPL17	-5749
RPL15	-5698
RPL32	-5598
RPL41	-5397
RPL18	-5360
RPL23A	-5246
RPL34	-5148
RPL7	-5057
RPL18A	-5015
RPL6	-4942
RPS23	-4940
RPS19	-4848
RPS3	-4842
RPL14	-4555
RPS15A	-4165
RPL27	-3935
RPL35	-3792
RPL39L	-3699
RPL39	-3539
RPS9	-3253
RPS24	-3138
RPS29	-3082
RPS27A	-2058
RPL35A	-1829
SEPHS2	-1784
RPS4Y1	-1198
RPS25	-545
RPL21	-383
RPS3A	-334
RPS13	-295
RPSA	-148
SECISBP2	526
RPS7	1197
RPS27L	1251
RPL22	1273
RPL24	1297
PSTK	1324
RPL3L	3763
SEPSECS	5248
RPL9	6370
RPL22L1	6595
RPL36A	6879

---

Regulation of expression of SLITs and ROBOs

Regulation of expression of SLITs and ROBOs

	1046
set	Regulation of expression of SLITs and ROBOs
setSize	163
pANOVA	3.95e-16
s.dist	-0.369
p.adjustANOVA	2.62e-14

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ROBO3	-9174
RPS4X	-9157
CASC3	-8770
RPLP2	-8715
RPL3	-8564
RPL23	-8406
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
PABPC1	-7807
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
PSMA7	-7617

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ROBO3	-9174
RPS4X	-9157
CASC3	-8770
RPLP2	-8715
RPL3	-8564
RPL23	-8406
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
PABPC1	-7807
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
PSMA7	-7617
PSMB7	-7580
PSMC3	-7538
RPL13	-7472
RPS18	-7468
RPL7A	-7394
RPS16	-7390
RPS10	-7354
RPL26	-7340
RPL10A	-7253
RPL30	-7217
RPS11	-7138
PSMD4	-7134
RPL4	-7127
FAU	-7067
RPL13A	-7019
PSMC5	-6942
RPS17	-6903
RPS15	-6758
RPL29	-6731
PSMD8	-6703
RPL36AL	-6668
ZSWIM8	-6567
RPS20	-6537
RPL38	-6495
RPL12	-6483
PSMB4	-6417
RPLP0	-6397
RPL10	-6333
RPL8	-6300
RPL5	-6221
RPL37A	-6135
RPL27A	-6113
LDB1	-5991
RPS2	-5959
RPS8	-5958
RPS21	-5899
RPL11	-5867
RPS27	-5866
RPLP1	-5846
RPS6	-5819
PSMD9	-5765
RPL17	-5749
RPL15	-5698
RPL32	-5598
ROBO1	-5521
PSMF1	-5494
RPL41	-5397
RPL18	-5360
PSMB3	-5327
ELOB	-5284
MAGOH	-5252
RPL23A	-5246
PSMD3	-5235
PSMB1	-5182
RPL34	-5148
PSMD7	-5070
RPL7	-5057
RPL18A	-5015
PSMD14	-4951
PSMB10	-4948
RPL6	-4942
RPS23	-4940
PSMC2	-4880
PSMB6	-4849
RPS19	-4848
RPS3	-4842
PSMD2	-4715
PSMA1	-4587
RPL14	-4555
PSMA5	-4364
PSMD10	-4338
PSMD1	-4278
RPS15A	-4165
RPL27	-3935
RNPS1	-3887
RPL35	-3792
RPL39L	-3699
GSPT2	-3673
RBX1	-3643
UPF3A	-3628
RPL39	-3539
PSMC4	-3510
RPS9	-3253
PSMB2	-3187
RPS24	-3138
RPS29	-3082
EIF4G1	-2994
UBB	-2810
UBC	-2608
PSMD6	-2563
ROBO2	-2493
PSMB5	-2492
PSMD13	-2447
RPS27A	-2058
RPL35A	-1829
PSME3	-1691
PSMC1	-1275
RPS4Y1	-1198
SLIT2	-819
SEM1	-739
PSME1	-634
CUL2	-617
RBM8A	-558
PSMA2	-550
RPS25	-545
RPL21	-383
PSMD11	-353
PSMB8	-350
RPS3A	-334
RPS13	-295
EIF4A3	-261
RPSA	-148
PSME4	609
DAG1	1118
RPS7	1197
ETF1	1218
RPS27L	1251
RPL22	1273
RPL24	1297
ELOC	1560
NCBP2	1609
PSMA6	1616
PSMA3	1706
UPF3B	1800
PSMC6	1856
UPF2	1902
GSPT1	2097
PSMD5	3165
PSME2	3291
NCBP1	3300
SLIT1	3728
RPL3L	3763
USP33	3940
PSMA4	4076
PSMB9	4260
PSMD12	4558
HOXA2	4950
LHX4	5925
RPL9	6370
MAGOHB	6565
RPL22L1	6595
RPL36A	6879
COL4A5	6962

---

Scavenging of heme from plasma

Scavenging of heme from plasma

	1124
set	Scavenging of heme from plasma
setSize	54
pANOVA	8.85e-16
s.dist	-0.632
p.adjustANOVA	5.6e-14

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
IGHV3-30	-8906

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
IGHV3-30	-8906
IGLV1-47	-8713
IGLV3-21	-8651
IGKV3-15	-8522
IGKV3-20	-8400
LRP1	-8228
IGLV2-23	-8106
IGHA2	-8079
CD163	-8028
IGLV3-19	-7984
IGHV4-59	-7466
IGKV2-30	-7018
IGKV4-1	-6785
IGLV6-57	-6578
IGLV1-40	-5992
IGHV4-39	-5760
IGKV2D-28	-5697
IGHV1-2	-5528
IGLV1-51	-5257
IGKC	-5210
IGHA1	-4732
IGKV1D-39	-4621
IGKV1-12	-4498
IGHV4-34	-3644
IGLV1-44	-1280
IGHV3-48	-616
IGKV1-16	-593
HBB	-144
HBA1	-36
IGHV3-23	658
JCHAIN	977
APOL1	2416
HP	3247
IGKV1-33	3826
HPX	4539

---

Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

	777
set	Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
setSize	94
pANOVA	9.29e-16
s.dist	-0.479
p.adjustANOVA	5.63e-14

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS4X	-9157
RPLP2	-8715
RPL3	-8564
RPL23	-8406
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
PABPC1	-7807
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
RPL13	-7472
RPS18	-7468
RPL7A	-7394

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS4X	-9157
RPLP2	-8715
RPL3	-8564
RPL23	-8406
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
PABPC1	-7807
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
RPL13	-7472
RPS18	-7468
RPL7A	-7394
RPS16	-7390
RPS10	-7354
RPL26	-7340
RPL10A	-7253
RPL30	-7217
RPS11	-7138
RPL4	-7127
FAU	-7067
RPL13A	-7019
RPS17	-6903
RPS15	-6758
RPL29	-6731
RPL36AL	-6668
RPS20	-6537
RPL38	-6495
RPL12	-6483
RPLP0	-6397
RPL10	-6333
RPL8	-6300
RPL5	-6221
RPL37A	-6135
RPL27A	-6113
RPS2	-5959
RPS8	-5958
RPS21	-5899
RPL11	-5867
RPS27	-5866
RPLP1	-5846
RPS6	-5819
RPL17	-5749
RPL15	-5698
RPL32	-5598
RPL41	-5397
RPL18	-5360
RPL23A	-5246
RPL34	-5148
RPL7	-5057
RPL18A	-5015
RPL6	-4942
RPS23	-4940
RPS19	-4848
RPS3	-4842
RPL14	-4555
RPS15A	-4165
RPL27	-3935
RPL35	-3792
RPL39L	-3699
GSPT2	-3673
RPL39	-3539
RPS9	-3253
RPS24	-3138
UPF1	-3106
RPS29	-3082
EIF4G1	-2994
RPS27A	-2058
RPL35A	-1829
RPS4Y1	-1198
RPS25	-545
RPL21	-383
RPS3A	-334
RPS13	-295
RPSA	-148
RPS7	1197
ETF1	1218
RPS27L	1251
RPL22	1273
RPL24	1297
NCBP2	1609
GSPT1	2097
NCBP1	3300
RPL3L	3763
RPL9	6370
RPL22L1	6595
RPL36A	6879

---

Viral mRNA Translation

Viral mRNA Translation

	1406
set	Viral mRNA Translation
setSize	88
pANOVA	1.8e-15
s.dist	-0.49
p.adjustANOVA	1.05e-13

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS4X	-9157
RPLP2	-8715
RPL3	-8564
RPL23	-8406
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
RPL13	-7472
RPS18	-7468
RPL7A	-7394
RPS16	-7390

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS4X	-9157
RPLP2	-8715
RPL3	-8564
RPL23	-8406
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
RPL13	-7472
RPS18	-7468
RPL7A	-7394
RPS16	-7390
RPS10	-7354
RPL26	-7340
RPL10A	-7253
RPL30	-7217
RPS11	-7138
RPL4	-7127
FAU	-7067
RPL13A	-7019
RPS17	-6903
RPS15	-6758
RPL29	-6731
RPL36AL	-6668
RPS20	-6537
RPL38	-6495
RPL12	-6483
RPLP0	-6397
RPL10	-6333
RPL8	-6300
RPL5	-6221
RPL37A	-6135
RPL27A	-6113
RPS2	-5959
RPS8	-5958
RPS21	-5899
RPL11	-5867
RPS27	-5866
RPLP1	-5846
RPS6	-5819
RPL17	-5749
RPL15	-5698
RPL32	-5598
RPL41	-5397
RPL18	-5360
RPL23A	-5246
RPL34	-5148
RPL7	-5057
RPL18A	-5015
RPL6	-4942
RPS23	-4940
RPS19	-4848
RPS3	-4842
RPL14	-4555
RPS15A	-4165
RPL27	-3935
RPL35	-3792
RPL39L	-3699
RPL39	-3539
RPS9	-3253
RPS24	-3138
RPS29	-3082
RPS27A	-2058
RPL35A	-1829
RPS4Y1	-1198
RPS25	-545
RPL21	-383
RPS3A	-334
RPS13	-295
RPSA	-148
RPS7	1197
RPS27L	1251
RPL22	1273
RPL24	1297
RPL3L	3763
DNAJC3	3962
GRSF1	4944
RPL9	6370
RPL22L1	6595
RPL36A	6879

---

SRP-dependent cotranslational protein targeting to membrane

SRP-dependent cotranslational protein targeting to membrane

	1106
set	SRP-dependent cotranslational protein targeting to membrane
setSize	111
pANOVA	8.97e-15
s.dist	-0.426
p.adjustANOVA	5.02e-13

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS4X	-9157
RPLP2	-8715
RPL3	-8564
RPL23	-8406
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
RPL26L1	-7694
SEC61A1	-7668
UBA52	-7643
RPS5	-7633
SSR4	-7533
RPL13	-7472
RPS18	-7468

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS4X	-9157
RPLP2	-8715
RPL3	-8564
RPL23	-8406
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
RPL26L1	-7694
SEC61A1	-7668
UBA52	-7643
RPS5	-7633
SSR4	-7533
RPL13	-7472
RPS18	-7468
RPL7A	-7394
RPS16	-7390
RPS10	-7354
RPL26	-7340
RPL10A	-7253
RPN1	-7232
RPL30	-7217
RPS11	-7138
RPL4	-7127
FAU	-7067
RPL13A	-7019
RPS17	-6903
RPS15	-6758
RPL29	-6731
SSR2	-6727
SRP68	-6707
RPL36AL	-6668
SRPRA	-6577
RPS20	-6537
RPL38	-6495
RPL12	-6483
RPLP0	-6397
RPL10	-6333
RPL8	-6300
RPL5	-6221
RPL37A	-6135
RPL27A	-6113
SRPRB	-6094
DDOST	-6043
RPS2	-5959
RPS8	-5958
RPS21	-5899
RPL11	-5867
RPS27	-5866
RPLP1	-5846
RPS6	-5819
RPL17	-5749
RPL15	-5698
RPL32	-5598
RPN2	-5586
RPL41	-5397
RPL18	-5360
RPL23A	-5246
RPL34	-5148
RPL7	-5057
RPL18A	-5015
RPL6	-4942
RPS23	-4940
RPS19	-4848
RPS3	-4842
RPL14	-4555
RPS15A	-4165
RPL27	-3935
RPL35	-3792
SEC61B	-3730
RPL39L	-3699
RPL39	-3539
RPS9	-3253
RPS24	-3138
RPS29	-3082
SRP72	-3081
RPS27A	-2058
RPL35A	-1829
SEC11C	-1765
SRP14	-1521
SSR3	-1475
RPS4Y1	-1198
RPS25	-545
RPL21	-383
RPS3A	-334
RPS13	-295
RPSA	-148
SEC11A	395
SSR1	1039
RPS7	1197
RPS27L	1251
RPL22	1273
RPL24	1297
SRP19	2192
SEC61A2	3459
RPL3L	3763
SRP9	4038
SPCS1	4118
SRP54	4227
SEC61G	4453
SPCS2	4543
TRAM1	4548
RPL9	6370
RPL22L1	6595
RPL36A	6879
SPCS3	8030

---

Selenoamino acid metabolism

Selenoamino acid metabolism

	1127
set	Selenoamino acid metabolism
setSize	115
pANOVA	1.17e-14
s.dist	-0.417
p.adjustANOVA	6.28e-13

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CBS	-9387
RPS4X	-9157
RPLP2	-8715
RPL3	-8564
PAPSS1	-8545
RPL23	-8406
RPS14	-8278
RPS12	-8256
EEFSEC	-8185
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
SARS1	-7485

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CBS	-9387
RPS4X	-9157
RPLP2	-8715
RPL3	-8564
PAPSS1	-8545
RPL23	-8406
RPS14	-8278
RPS12	-8256
EEFSEC	-8185
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
SARS1	-7485
RPL13	-7472
RPS18	-7468
RPL7A	-7394
RPS16	-7390
RPS10	-7354
RPL26	-7340
RPL10A	-7253
RPL30	-7217
RPS11	-7138
RPL4	-7127
FAU	-7067
RPL13A	-7019
RPS17	-6903
RPS15	-6758
RPL29	-6731
QARS1	-6720
RPL36AL	-6668
RPS20	-6537
RPL38	-6495
RPL12	-6483
RPLP0	-6397
RPL10	-6333
MARS1	-6302
RPL8	-6300
RPL5	-6221
RPL37A	-6135
RPL27A	-6113
RPS2	-5959
RPS8	-5958
RPS21	-5899
RPL11	-5867
RPS27	-5866
RPLP1	-5846
RPS6	-5819
RPL17	-5749
RPL15	-5698
RPL32	-5598
RPL41	-5397
AHCY	-5382
RPL18	-5360
RPL23A	-5246
RPL34	-5148
RPL7	-5057
RPL18A	-5015
RPL6	-4942
RPS23	-4940
RPS19	-4848
RPS3	-4842
RPL14	-4555
RPS15A	-4165
RPL27	-3935
RPL35	-3792
RPL39L	-3699
RPL39	-3539
CTH	-3415
NNMT	-3409
KARS1	-3275
RPS9	-3253
RPS24	-3138
RPS29	-3082
SCLY	-2498
RPS27A	-2058
PAPSS2	-1870
RPL35A	-1829
SEPHS2	-1784
RPS4Y1	-1198
IARS1	-664
RPS25	-545
EPRS1	-493
RPL21	-383
RPS3A	-334
RPS13	-295
RPSA	-148
RARS1	-147
HNMT	85
GNMT	225
SECISBP2	526
AIMP1	1167
RPS7	1197
RPS27L	1251
RPL22	1273
RPL24	1297
GSR	1306
PSTK	1324
TXNRD1	2385
AIMP2	2640
DARS1	2769
INMT	2937
RPL3L	3763
SEPSECS	5248
EEF1E1	5800
LARS1	6265
RPL9	6370
RPL22L1	6595
RPL36A	6879

---

Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

	776
set	Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
setSize	114
pANOVA	1.65e-14
s.dist	-0.416
p.adjustANOVA	8.26e-13

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS4X	-9157
CASC3	-8770
RPLP2	-8715
RPL3	-8564
RPL23	-8406
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
PABPC1	-7807
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
SMG9	-7490
RPL13	-7472

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS4X	-9157
CASC3	-8770
RPLP2	-8715
RPL3	-8564
RPL23	-8406
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
PABPC1	-7807
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
SMG9	-7490
RPL13	-7472
RPS18	-7468
RPL7A	-7394
RPS16	-7390
RPS10	-7354
RPL26	-7340
RPL10A	-7253
RPL30	-7217
RPS11	-7138
RPL4	-7127
FAU	-7067
RPL13A	-7019
RPS17	-6903
RPS15	-6758
RPL29	-6731
RPL36AL	-6668
RPS20	-6537
RPL38	-6495
RPL12	-6483
PPP2R1A	-6433
RPLP0	-6397
RPL10	-6333
RPL8	-6300
RPL5	-6221
RPL37A	-6135
RPL27A	-6113
SMG6	-5978
RPS2	-5959
RPS8	-5958
RPS21	-5899
RPL11	-5867
RPS27	-5866
RPLP1	-5846
RPS6	-5819
RPL17	-5749
RPL15	-5698
RPL32	-5598
RPL41	-5397
RPL18	-5360
MAGOH	-5252
RPL23A	-5246
RPL34	-5148
RPL7	-5057
RPL18A	-5015
RPL6	-4942
RPS23	-4940
RPS19	-4848
RPS3	-4842
RPL14	-4555
SMG8	-4290
RPS15A	-4165
RPL27	-3935
RNPS1	-3887
RPL35	-3792
RPL39L	-3699
GSPT2	-3673
UPF3A	-3628
RPL39	-3539
RPS9	-3253
SMG5	-3218
RPS24	-3138
UPF1	-3106
RPS29	-3082
EIF4G1	-2994
RPS27A	-2058
RPL35A	-1829
RPS4Y1	-1198
PPP2CA	-765
RBM8A	-558
RPS25	-545
RPL21	-383
RPS3A	-334
RPS13	-295
EIF4A3	-261
RPSA	-148
SMG7	1071
RPS7	1197
ETF1	1218
RPS27L	1251
RPL22	1273
RPL24	1297
NCBP2	1609
UPF3B	1800
PPP2R2A	1826
UPF2	1902
GSPT1	2097
NCBP1	3300
DCP1A	3372
RPL3L	3763
PNRC2	4126
RPL9	6370
MAGOHB	6565
RPL22L1	6595
RPL36A	6879
SMG1	6931

---

Nonsense-Mediated Decay (NMD)

Nonsense-Mediated Decay (NMD)

	778
set	Nonsense-Mediated Decay (NMD)
setSize	114
pANOVA	1.65e-14
s.dist	-0.416
p.adjustANOVA	8.26e-13

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS4X	-9157
CASC3	-8770
RPLP2	-8715
RPL3	-8564
RPL23	-8406
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
PABPC1	-7807
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
SMG9	-7490
RPL13	-7472

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS4X	-9157
CASC3	-8770
RPLP2	-8715
RPL3	-8564
RPL23	-8406
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
PABPC1	-7807
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
SMG9	-7490
RPL13	-7472
RPS18	-7468
RPL7A	-7394
RPS16	-7390
RPS10	-7354
RPL26	-7340
RPL10A	-7253
RPL30	-7217
RPS11	-7138
RPL4	-7127
FAU	-7067
RPL13A	-7019
RPS17	-6903
RPS15	-6758
RPL29	-6731
RPL36AL	-6668
RPS20	-6537
RPL38	-6495
RPL12	-6483
PPP2R1A	-6433
RPLP0	-6397
RPL10	-6333
RPL8	-6300
RPL5	-6221
RPL37A	-6135
RPL27A	-6113
SMG6	-5978
RPS2	-5959
RPS8	-5958
RPS21	-5899
RPL11	-5867
RPS27	-5866
RPLP1	-5846
RPS6	-5819
RPL17	-5749
RPL15	-5698
RPL32	-5598
RPL41	-5397
RPL18	-5360
MAGOH	-5252
RPL23A	-5246
RPL34	-5148
RPL7	-5057
RPL18A	-5015
RPL6	-4942
RPS23	-4940
RPS19	-4848
RPS3	-4842
RPL14	-4555
SMG8	-4290
RPS15A	-4165
RPL27	-3935
RNPS1	-3887
RPL35	-3792
RPL39L	-3699
GSPT2	-3673
UPF3A	-3628
RPL39	-3539
RPS9	-3253
SMG5	-3218
RPS24	-3138
UPF1	-3106
RPS29	-3082
EIF4G1	-2994
RPS27A	-2058
RPL35A	-1829
RPS4Y1	-1198
PPP2CA	-765
RBM8A	-558
RPS25	-545
RPL21	-383
RPS3A	-334
RPS13	-295
EIF4A3	-261
RPSA	-148
SMG7	1071
RPS7	1197
ETF1	1218
RPS27L	1251
RPL22	1273
RPL24	1297
NCBP2	1609
UPF3B	1800
PPP2R2A	1826
UPF2	1902
GSPT1	2097
NCBP1	3300
DCP1A	3372
RPL3L	3763
PNRC2	4126
RPL9	6370
MAGOHB	6565
RPL22L1	6595
RPL36A	6879
SMG1	6931

---

Influenza Viral RNA Transcription and Replication

Influenza Viral RNA Transcription and Replication

	557
set	Influenza Viral RNA Transcription and Replication
setSize	135
pANOVA	2.15e-14
s.dist	-0.381
p.adjustANOVA	1.04e-12

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GTF2F1	-9321
RPS4X	-9157
AAAS	-9006
RPLP2	-8715
RPL3	-8564
SEC13	-8457
RPL23	-8406
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
RPL26L1	-7694
NUP188	-7684
POLR2G	-7651
UBA52	-7643

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GTF2F1	-9321
RPS4X	-9157
AAAS	-9006
RPLP2	-8715
RPL3	-8564
SEC13	-8457
RPL23	-8406
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
RPL26L1	-7694
NUP188	-7684
POLR2G	-7651
UBA52	-7643
RPS5	-7633
RPL13	-7472
RPS18	-7468
POLR2F	-7453
RPL7A	-7394
RPS16	-7390
RPS10	-7354
NUP85	-7351
RPL26	-7340
RPL10A	-7253
RPL30	-7217
RPS11	-7138
RPL4	-7127
FAU	-7067
RPL13A	-7019
POLR2H	-6957
RPS17	-6903
RPS15	-6758
RPL29	-6731
RPL36AL	-6668
RPS20	-6537
RPL38	-6495
RPL12	-6483
RPLP0	-6397
RPL10	-6333
RPL8	-6300
POM121	-6225
RPL5	-6221
RPL37A	-6135
RPL27A	-6113
RPS2	-5959
RPS8	-5958
RPS21	-5899
RPL11	-5867
RPS27	-5866
RPLP1	-5846
RPS6	-5819
RPL17	-5749
RPL15	-5698
RPL32	-5598
RPL41	-5397
RPL18	-5360
RPL23A	-5246
RPL34	-5148
RPL7	-5057
RPL18A	-5015
RPL6	-4942
RPS23	-4940
RPS19	-4848
RPS3	-4842
POLR2I	-4811
POLR2C	-4802
NUP62	-4588
RPL14	-4555
TPR	-4504
POLR2E	-4389
IPO5	-4347
NUP214	-4176
RPS15A	-4165
RPL27	-3935
RAE1	-3807
RPL35	-3792
RPL39L	-3699
NUP88	-3689
POM121C	-3677
RPL39	-3539
NUP98	-3400
POLR2J	-3355
RPS9	-3253
PARP1	-3200
NUP93	-3163
RPS24	-3138
RPS29	-3082
NUP43	-2946
HSP90AA1	-2745
POLR2L	-2358
RPS27A	-2058
GTF2F2	-2047
RPL35A	-1829
POLR2D	-1531
POLR2A	-1215
RPS4Y1	-1198
RPS25	-545
RPL21	-383
POLR2B	-362
RPS3A	-334
RPS13	-295
RPSA	-148
NUP155	-51
NUP42	299
NUP205	808
RPS7	1197
RPS27L	1251
RPL22	1273
RPL24	1297
NUP210	1376
NUP153	1582
NUP160	1654
NUP54	2334
NUP35	2637
POLR2K	3276
RPL3L	3763
DNAJC3	3962
NDC1	4688
NUP133	4739
NUP107	4939
GRSF1	4944
RANBP2	5097
NUP37	5735
NUP50	5855
SEH1L	6077
RPL9	6370
RPL22L1	6595
RPL36A	6879
NUP58	8794

---

CD22 mediated BCR regulation

CD22 mediated BCR regulation

	127
set	CD22 mediated BCR regulation
setSize	48
pANOVA	2.26e-14
s.dist	-0.637
p.adjustANOVA	1.06e-12

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV2-14	-9482
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGHD	-9294
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
IGHV3-30	-8906
IGLV1-47	-8713
IGLV3-21	-8651

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV2-14	-9482
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGHD	-9294
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
IGHV3-30	-8906
IGLV1-47	-8713
IGLV3-21	-8651
IGKV3-15	-8522
IGKV3-20	-8400
IGLV2-23	-8106
IGLV3-19	-7984
IGHV4-59	-7466
IGHM	-7430
IGKV2-30	-7018
IGKV4-1	-6785
IGLV6-57	-6578
IGLV1-40	-5992
PTPN6	-5990
IGHV4-39	-5760
IGKV2D-28	-5697
IGHV1-2	-5528
IGLV1-51	-5257
IGKC	-5210
IGKV1D-39	-4621
IGKV1-12	-4498
IGHV4-34	-3644
CD79A	-3007
CD79B	-1501
IGLV1-44	-1280
IGHV3-48	-616
IGKV1-16	-593
IGHV3-23	658
IGKV1-33	3826
CD22	6773
LYN	8170

---

rRNA processing

rRNA processing

	1446
set	rRNA processing
setSize	214
pANOVA	2.83e-14
s.dist	-0.302
p.adjustANOVA	1.29e-12

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PWP2	-9356
NOP2	-9329
NOL12	-9160
RPS4X	-9157
PES1	-9076
WDR46	-9022
DHX37	-8992
UTP3	-8901
FTSJ3	-8731
RPLP2	-8715
RRP9	-8711
RPP25	-8676
NOB1	-8667
EXOSC7	-8626
RPL3	-8564
NOL6	-8490
RPP38	-8462
RPL23	-8406
RPS14	-8278
DDX49	-8262

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PWP2	-9356
NOP2	-9329
NOL12	-9160
RPS4X	-9157
PES1	-9076
WDR46	-9022
DHX37	-8992
UTP3	-8901
FTSJ3	-8731
RPLP2	-8715
RRP9	-8711
RPP25	-8676
NOB1	-8667
EXOSC7	-8626
RPL3	-8564
NOL6	-8490
RPP38	-8462
RPL23	-8406
RPS14	-8278
DDX49	-8262
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RRP1	-7943
RPL37	-7930
RPP21	-7916
RPS26	-7908
RPL31	-7842
LAS1L	-7790
WDR18	-7755
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
EBNA1BP2	-7528
CSNK1E	-7502
RPL13	-7472
RPS18	-7468
RPL7A	-7394
RPS16	-7390
NCL	-7363
RPS10	-7354
RPL26	-7340
HSD17B10	-7304
RPL10A	-7253
RPL30	-7217
TBL3	-7214
BMS1	-7180
RPS11	-7138
RPL4	-7127
FAU	-7067
RPL13A	-7019
NAT10	-6956
NOP14	-6926
RPS17	-6903
EXOSC2	-6796
RPS15	-6758
RPL29	-6731
TRMT112	-6708
RPL36AL	-6668
MTERF4	-6607
UTP14A	-6554
RPS20	-6537
RPL38	-6495
RPL12	-6483
CSNK1D	-6427
RPLP0	-6397
FBL	-6366
RPL10	-6333
RPL8	-6300
DKC1	-6279
RPL5	-6221
EXOSC1	-6182
RPL37A	-6135
RPL27A	-6113
RRP36	-6103
RPS2	-5959
RPS8	-5958
NOC4L	-5927
RPS21	-5899
RPL11	-5867
RPS27	-5866
RPLP1	-5846
RPS6	-5819
UTP4	-5802
RPL17	-5749
RPL15	-5698
EXOSC10	-5673
RPL32	-5598
IMP4	-5469
RPL41	-5397
BOP1	-5385
RPL18	-5360
EXOSC4	-5333
IMP3	-5301
RCL1	-5265
RPL23A	-5246
NHP2	-5244
RPL34	-5148
RPL7	-5057
RPL18A	-5015
PELP1	-5004
RPL6	-4942
RPS23	-4940
MRM1	-4933
RPS19	-4848
RPS3	-4842
NOP56	-4726
SNU13	-4584
RPL14	-4555
NOP10	-4184
RPS15A	-4165
EMG1	-3956
RPL27	-3935
RPL35	-3792
MRM2	-3702
RPL39L	-3699
RPL39	-3539
RPS9	-3253
UTP25	-3217
EXOSC5	-3179
BYSL	-3140
RPS24	-3138
RPS29	-3082
MRM3	-2812
PDCD11	-2693
TSR3	-2647
ELAC2	-2557
EXOSC3	-2536
WDR12	-2378
UTP18	-2303
RPS27A	-2058
TSR1	-2001
RPP40	-1863
EXOSC6	-1847
RPL35A	-1829
RRP7A	-1767
RBM28	-1756
NIP7	-1693
XRN2	-1560
SENP3	-1401
GNL3	-1329
LTV1	-1318
RPS4Y1	-1198
PRORP	-1052
RIOK2	-891
NSUN4	-779
UTP14C	-777
RPS25	-545
DCAF13	-448
RPL21	-383
RPS3A	-334
RPS13	-295
RPSA	-148
NOL11	-105
DIMT1	-58
UTP20	94
WDR43	176
ISG20L2	384
MT-ND4L	673
DDX47	693
PNO1	843
WDR3	916
RPS7	1197
RPS27L	1251
RPL22	1273
RPL24	1297
RIOK1	1448
NOL9	1697
EXOSC9	1963
UTP6	2380
MT-ATP8	2391
DIS3	2583
FCF1	2588
EXOSC8	2653
RPP14	2689
HEATR1	2886
MTREX	3201
ERI1	3312
RPL3L	3763
RPP30	3814
MT-ATP6	3857
TRMT10C	3872
NOP58	4137
GAR1	4148
TEX10	4243
MT-CO1	4282
MT-CO2	4296
MPHOSPH6	4600
WDR75	4848
MT-ND5	5007
MT-CYB	5065
UTP11	5716
WDR36	5894
THUMPD1	5914
RIOK3	6036
KRR1	6130
MPHOSPH10	6348
RPL9	6370
TFB1M	6373
DDX21	6458
RPL22L1	6595
UTP15	6799
RPL36A	6879
MT-ND4	6917
DDX52	6981
MT-ND2	7484
MT-ND1	7626
MT-RNR1	7788
MT-CO3	8009
C1D	8221
MT-ND3	8619
MT-RNR2	9249

---

Disease

Disease

	301
set	Disease
setSize	1456
pANOVA	5.06e-14
s.dist	-0.118
p.adjustANOVA	2.23e-12

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MUC20	-9538
IGLV3-1	-9534
IGLV5-45	-9525
SLC25A6	-9520
MUC6	-9492
IGLV2-14	-9482
IGLV8-61	-9471
GSDME	-9459
THBS2	-9455
IGLV7-46	-9444
F10	-9439
MUC12	-9426
IGKV1-5	-9421
IGLC3	-9405
FN1	-9363
IGHV3-7	-9357
IGKV3-11	-9342
VAMP1	-9324
GTF2F1	-9321
IGLV2-8	-9316

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MUC20	-9538
IGLV3-1	-9534
IGLV5-45	-9525
SLC25A6	-9520
MUC6	-9492
IGLV2-14	-9482
IGLV8-61	-9471
GSDME	-9459
THBS2	-9455
IGLV7-46	-9444
F10	-9439
MUC12	-9426
IGKV1-5	-9421
IGLC3	-9405
FN1	-9363
IGHV3-7	-9357
IGKV3-11	-9342
VAMP1	-9324
GTF2F1	-9321
IGLV2-8	-9316
H2BC12	-9313
IGHV2-5	-9310
IGLC1	-9301
PRELP	-9299
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
ADAMTSL4	-9245
DKK1	-9225
NT5E	-9206
CDKN2A	-9194
GPBAR1	-9186
PTHLH	-9182
DCN	-9178
H2AW	-9173
FXYD2	-9172
RPS4X	-9157
CTSG	-9144
PTH2R	-9125
IGLC2	-9098
SLC2A10	-9052
SDC2	-9050
IGHV3-11	-9041
SLC9A9	-9026
FXYD6	-9023
SERPING1	-9016
IGHG2	-9010
AAAS	-9006
CDC25B	-8996
AP1M1	-8972
POMT2	-8968
AP2A2	-8966
GALNT12	-8937
CYP21A2	-8924
IGHV3-30	-8906
SRC	-8900
SSRP1	-8890
FGFR2	-8879
STX1B	-8864
SPON2	-8862
SGSH	-8851
FGF16	-8850
SIGMAR1	-8836
SLC35C1	-8814
ADAMTS13	-8796
GCKR	-8794
IGHG3	-8775
SNF8	-8773
ABL1	-8744
RPLP2	-8715
IGLV1-47	-8713
DPM2	-8704
IGLV3-21	-8651
CYP26B1	-8642
CDK4	-8617
CHMP2A	-8605
PRKCSH	-8602
MOGS	-8596
GUSB	-8594
GTF2E2	-8588
VEGFA	-8586
CD4	-8579
COMT	-8571
RPL3	-8564
PAPSS1	-8545
IGKV3-15	-8522
DVL2	-8480
ABCA3	-8474
NOX4	-8461
SEC13	-8457
NELFB	-8452
ACTG1	-8451
EXT1	-8440
IGHG4	-8417
STX1A	-8416
PORCN	-8415
RPL23	-8406
IGKV3-20	-8400
ADAMTS10	-8398
IDUA	-8383
SLC22A18	-8355
FGFR1	-8341
ALG3	-8328
SPON1	-8313
SH3GL1	-8287
HGS	-8283
C3AR1	-8279
RPS14	-8278
OGG1	-8266
SYVN1	-8265
RPS12	-8256
RRBP1	-8253
HDAC7	-8251
ADCY6	-8246
ANTXR1	-8240
B3GAT3	-8238
SUPT16H	-8220
HSPG2	-8195
RPL36	-8166
CTDP1	-8161
CHD3	-8140
FRS3	-8137
RPL19	-8133
RPS28	-8128
IGLV2-23	-8106
DCTN1	-8089
ADCY7	-8082
ITGB3	-8067
ST3GAL4	-8065
KAT5	-8042
RPL28	-8031
CD163	-8028
EEF2	-8011
IGLV3-19	-7984
PMM2	-7976
TFG	-7967
PTH1R	-7949
MTA1	-7942
GSS	-7941
RPL37	-7930
TLR5	-7910
RPS26	-7908
SLC3A2	-7899
CTSL	-7889
FYN	-7874
NELFE	-7873
TIRAP	-7859
STAT5A	-7852
RPL31	-7842
BAIAP2	-7819
OS9	-7797
PDGFRB	-7793
PARP6	-7777
ITGA2B	-7775
PDCD1	-7767
ADAMTS17	-7765
HDAC3	-7742
GOLGA2	-7731
TLR9	-7728
LRP5	-7717
HDAC6	-7713
CUBN	-7712
ALG12	-7699
RPL26L1	-7694
GAA	-7692
B3GALT6	-7687
CFP	-7685
NUP188	-7684
ADAMTS16	-7666
POLR2G	-7651
UBA52	-7643
DAXX	-7642
ADAMTS2	-7639
RPS5	-7633
ANAPC2	-7619
NCKIPSD	-7618
PSMA7	-7617
TAF15	-7616
CD14	-7606
HDAC10	-7600
PDGFRA	-7589
PSMB7	-7580
CHMP4A	-7578
IKBKG	-7562
PSMC3	-7538
TUBB	-7529
GNB2	-7507
SUPT5H	-7505
CHST3	-7500
UBE2I	-7499
MPI	-7493
WASF1	-7486
RPL13	-7472
RPS18	-7468
IGHV4-59	-7466
POLR2F	-7453
VPS25	-7451
CAPN1	-7420
ATG7	-7408
DPM3	-7400
RPL7A	-7394
RPS16	-7390
NELFA	-7389
UNC93B1	-7377
TRIM28	-7371
VPS28	-7361
RPS10	-7354
NUP85	-7351
GALK1	-7346
RPL26	-7340
AP2A1	-7331
SLC1A3	-7312
WASF2	-7299
GPC3	-7281
CTBP1	-7277
ARF1	-7273
RPL10A	-7253
KLC1	-7249
RPN1	-7232
RPL30	-7217
SPTBN1	-7208
AP2M1	-7207
LMNA	-7191
ACTB	-7187
GANAB	-7181
KREMEN1	-7171
SCTR	-7153
ARPC1A	-7142
RPS11	-7138
PSMD4	-7134
RPL4	-7127
AXIN1	-7095
FZR1	-7074
FAU	-7067
AP1B1	-7052
ABCC2	-7046
SEC31A	-7037
MUC4	-7036
CSPG5	-7032
RPL13A	-7019
IGKV2-30	-7018
HEXA	-7007
MYO9B	-6996
ANAPC11	-6992
APH1A	-6986
AKT1	-6976
POLR2H	-6957
GNAI2	-6950
PSMC5	-6942
ADAMTS14	-6930
MTA3	-6916
RPS17	-6903
AGTRAP	-6891
GTF2H4	-6879
ARPC1B	-6869
AKT2	-6860
CALR	-6854
CDK9	-6851
GNB1	-6844
CHST14	-6822
NOTCH2	-6821
RHOG	-6819
IGKV4-1	-6785
CTSA	-6775
RPS15	-6758
GPS2	-6743
DVL3	-6742
RPL29	-6731
CLCN6	-6716
PSMD8	-6703
CDKN1C	-6700
PHB	-6696
CHMP1A	-6691
RPL36AL	-6668
BRK1	-6636
PIK3R2	-6618
IGLV6-57	-6578
HDAC5	-6562
GNAS	-6561
CSF2RA	-6546
RPS20	-6537
MLST8	-6519
RPL38	-6495
EDEM2	-6490
RPL12	-6483
SLC35A2	-6445
PPP2R1A	-6433
PRR5	-6419
PSMB4	-6417
ERBB2	-6416
MYO1C	-6410
RPLP0	-6397
TSC2	-6377
B4GAT1	-6368
RPL10	-6333
MGAT4B	-6306
RANBP1	-6303
RPL8	-6300
ADCY3	-6292
HGSNAT	-6288
DOLK	-6281
ISG15	-6233
POM121	-6225
RPL5	-6221
VPS33B	-6196
HEXB	-6186
BSG	-6157
TOP3A	-6149
RPL37A	-6135
MC1R	-6117
EGFR	-6115
RPL27A	-6113
DOCK1	-6096
CHMP4B	-6078
ADAMTSL1	-6076
SLC29A3	-6059
DDOST	-6043
NMT1	-6029
C3	-5996
IGLV1-40	-5992
MAPK3	-5987
ITPR3	-5979
NCOR2	-5973
RPS2	-5959
RPS8	-5958
GOLGB1	-5951
P2RX4	-5904
RPS21	-5899
CARS1	-5897
SDC1	-5891
IMPDH2	-5882
GSK3A	-5880
PARP16	-5876
RPL11	-5867
RPS27	-5866
B4GALT7	-5857
MAN1B1	-5852
RPLP1	-5846
RPS6	-5819
ATIC	-5803
SIN3A	-5782
CCND2	-5776
ERLIN1	-5772
DUSP16	-5770
SLC39A4	-5767
PSMD9	-5765
IGHV4-39	-5760
RPL17	-5749
FGF22	-5744
G6PC3	-5729
TICAM1	-5708
RPL15	-5698
IGKV2D-28	-5697
HMG20B	-5680
TRAF3	-5679
VPS4A	-5655
IDS	-5638
ZFYVE9	-5632
RPL32	-5598
AP2B1	-5595
PPP2R5D	-5593
MGAT1	-5591
RPN2	-5586
ADAMTS7	-5570
HSP90AB1	-5567
TRADD	-5562
PYCARD	-5560
FOXO4	-5542
AP2S1	-5530
IGHV1-2	-5528
BRMS1	-5517
VCAN	-5502
PSMF1	-5494
CREBBP	-5487
POMC	-5478
RANGAP1	-5460
XRCC6	-5440
IFNGR2	-5433
RBBP7	-5415
SND1	-5406
RPL41	-5397
RCC1	-5394
AHCY	-5382
MAPKAP1	-5368
IMPDH1	-5362
RPL18	-5360
FLT3	-5346
AGRN	-5337
ALG1	-5332
PSMB3	-5327
CHD4	-5297
PABPN1	-5294
MAOA	-5293
ELOB	-5284
IGHG1	-5275
MBD3	-5274
IGLV1-51	-5257
CHMP3	-5253
RPL23A	-5246
RNMT	-5242
PSMD3	-5235
FZD7	-5230
FLT3LG	-5226
AP1S1	-5221
MPDU1	-5217
STT3A	-5213
IGKC	-5210
KPNA2	-5200
ARPC2	-5195
NHLRC1	-5192
CYP27A1	-5186
PSMB1	-5182
CAST	-5157
RPL34	-5148
FMOD	-5144
HK1	-5138
UVRAG	-5130
PARP10	-5128
DNMT1	-5127
TYK2	-5124
SUPT4H1	-5123
FASLG	-5113
FURIN	-5091
ST6GALNAC4	-5073
PSMD7	-5070
GCK	-5069
TFDP2	-5065
ABCB6	-5062
GPR20	-5058
RPL7	-5057
RNF185	-5027
CLTA	-5023
MAP2K7	-5020
RIPK1	-5016
RPL18A	-5015
CHMP6	-4996
APP	-4981
SLC27A4	-4977
DCXR	-4957
PSMD14	-4951
PSMB10	-4948
RPL6	-4942
RPS23	-4940
ARRB1	-4930
SFTPD	-4929
MYO5A	-4904
RAN	-4882
PSMC2	-4880
PSMB6	-4849
RPS19	-4848
GATAD2A	-4846
RPS3	-4842
TLN1	-4831
NTHL1	-4814
POLR2I	-4811
POLR2C	-4802
HMOX1	-4801
FOXO6	-4770
KHK	-4767
IRS2	-4756
NEU1	-4754
MRC1	-4738
GAB2	-4727
CSK	-4717
PSMD2	-4715
CDC25A	-4711
CYSLTR2	-4710
KSR1	-4647
PACS1	-4639
VCP	-4638
ANTXR2	-4636
IGKV1D-39	-4621
SLC17A5	-4597
CAPNS1	-4591
HRAS	-4590
NUP62	-4588
PSMA1	-4587
ERCC3	-4568
MVB12B	-4567
FDXR	-4565
MAP2K2	-4556
RPL14	-4555
CDC26	-4540
TPR	-4504
APBB1IP	-4502
NAGLU	-4499
IGKV1-12	-4498
GALT	-4454
KIT	-4439
DYNC1H1	-4438
POLR2E	-4389
PSMA5	-4364
MUTYH	-4361
ADORA2B	-4358
IKBKB	-4349
IPO5	-4347
MAML3	-4346
PSMD10	-4338
ARAF	-4322
DUSP7	-4308
TBXAS1	-4294
TAF6	-4292
CASP9	-4280
PSMD1	-4278
AP3B1	-4267
FADD	-4243
MTOR	-4239
KEAP1	-4234
TAF9	-4231
POMT1	-4224
PALB2	-4190
NUP214	-4176
RPS15A	-4165
DYNC1I2	-4164
BAD	-4140
DBP	-4134
KANK1	-4120
ABCD1	-4104
IL18	-4093
WASF3	-4071
LUM	-4064
EXT2	-4054
DYNLL1	-4027
SQSTM1	-4008
PC	-4006
NCSTN	-3999
RAMP2	-3984
GALNS	-3976
FDX2	-3970
FIP1L1	-3969
BTD	-3962
VAV1	-3953
ELOA	-3947
RPL27	-3935
BECN1	-3914
DHDDS	-3891
ARPC4	-3888
PARP4	-3881
CUL1	-3857
RAE1	-3807
BTRC	-3803
LFNG	-3797
RPL35	-3792
PSTPIP1	-3791
CDC16	-3785
MYD88	-3784
TGFB1	-3765
PRMT1	-3758
HHAT	-3753
CSPG4	-3747
SLC4A1	-3716
RPL39L	-3699
NUP88	-3689
H2AJ	-3688
POM121C	-3677
VAMP2	-3662
VPS37C	-3658
BTK	-3657
MAML2	-3647
IGHV4-34	-3644
RBX1	-3643
FXYD1	-3636
ANAPC5	-3632
FEN1	-3621
GLP2R	-3617
PPIA	-3610
ATP1A1	-3606
TAF10	-3596
SLC11A2	-3573
TRIM27	-3563
AVPR2	-3554
MIB2	-3549
TXNIP	-3546
RPL39	-3539
NFKB1	-3526
PSMC4	-3510
OPLAH	-3491
DOCK2	-3489
LTF	-3487
CD320	-3476
SLC25A5	-3474
PHF21A	-3462
ALG2	-3461
AMN	-3420
MTA2	-3401
NUP98	-3400
HYAL1	-3376
MGAT2	-3375
MVB12A	-3360
POLR2J	-3355
RAD51D	-3339
PEBP1	-3327
ARSB	-3324
PLCG1	-3308
NCKAP1L	-3307
CPSF4	-3300
RNF5	-3276
GYG2	-3259
RPS9	-3253
PPP2CB	-3249
NELFCD	-3248
BRD4	-3231
SDC3	-3226
SH3KBP1	-3219
GNG7	-3213
PSEN1	-3202
PARP1	-3200
PSMB2	-3187
CLTC	-3186
MGAT5	-3183
NCOR1	-3170
RHBDF2	-3167
NUP93	-3163
CHMP7	-3149
RPS24	-3138
CYFIP1	-3125
DRD1	-3120
BTC	-3119
TP53	-3110
FGFR3	-3094
RPS6KB2	-3084
RPS29	-3082
EEF1G	-3076
CPSF6	-3059
ST3GAL3	-3046
FNTB	-3027
VPS37D	-3017
RELA	-3015
CTBP2	-2996
ST6GAL1	-2961
NUP43	-2946
KDM1A	-2926
MRAS	-2913
ADCY5	-2906
BCL2L1	-2902
DVL1	-2895
HLA-A	-2891
SPRED2	-2862
ADAMTSL5	-2858
ESR1	-2842
UBB	-2810
RAC1	-2805
BGN	-2800
GGT1	-2784
MECP2	-2782
RAD51	-2775
RBBP8	-2774
HSP90AA1	-2745
TRAF2	-2715
TCF7L2	-2708
ADAMTS12	-2706
SLC2A1	-2646
DPAGT1	-2639
CDC37	-2632
UBC	-2608
ENO1	-2605
PIK3R1	-2575
TALDO1	-2571
PSMD6	-2563
GNG2	-2555
KPNB1	-2542
RHAG	-2531
ABCD4	-2525
PSMB5	-2492
ARRB2	-2487
ERCC2	-2482
PSENEN	-2481
ELMO2	-2473
E2F1	-2460
PCCA	-2457
WDCP	-2453
PSMD13	-2447
SLC16A1	-2417
POLR2L	-2358
GGT5	-2348
HMGA1	-2228
HDAC11	-2222
MAP3K11	-2175
HIP1	-2169
PDGFB	-2165
HLCS	-2150
MSN	-2128
MAML1	-2111
GP1BB	-2082
RPS27A	-2058
GNAI1	-2057
GTF2F2	-2047
SLC24A1	-2042
AKT1S1	-2032
CYBA	-1998
PRKACA	-1995
SMAD3	-1989
GALE	-1982
SAP18	-1972
BCR	-1971
MSH3	-1956
KIAA1549	-1955
MPRIP	-1954
MAP2K3	-1950
SLC2A9	-1935
RBP1	-1933
FMO3	-1903
NEDD4L	-1891
CCND3	-1889
PAPSS2	-1870
ELK1	-1858
RDH5	-1853
DERL1	-1851
LCK	-1841
EPM2A	-1830
RPL35A	-1829
FGF10	-1825
FGF18	-1814
ABCB4	-1811
MNAT1	-1809
ADAMTS6	-1799
MYH2	-1794
CUX1	-1771
MARK3	-1770
APOBEC3G	-1749
SNW1	-1709
TBL1X	-1706
PSME3	-1691
SV2A	-1676
MAMLD1	-1657
NRG2	-1656
AHCYL1	-1655
TENT4A	-1649
VAV2	-1647
TSG101	-1644
DUT	-1640
YWHAE	-1609
BDNF	-1600
CBX1	-1599
PMS2	-1593
TPST2	-1578
CYP11A1	-1566
TGFBR2	-1532
POLR2D	-1531
ADCY9	-1529
CAPN2	-1447
GSDMD	-1439
ZC3HC1	-1437
GNE	-1426
JAG2	-1415
PRKAR2B	-1412
NMT2	-1397
ACAN	-1392
PML	-1391
PCCB	-1364
SLC20A2	-1358
ELL	-1355
GPR176	-1349
CDC23	-1342
EP300	-1330
MCCC2	-1327
FKBP4	-1306
SAP30L	-1293
IGLV1-44	-1280
PSMC1	-1275
MUC1	-1266
ANAPC10	-1260
GPC6	-1226
ACY1	-1225
AMER1	-1224
S100A1	-1219
POLR2A	-1215
SYK	-1210
TAF4	-1203
RPS4Y1	-1198
VIPR1	-1174
DERL3	-1157
PSEN2	-1147
TCN2	-1138
BRAP	-1130
LARGE1	-1084
SLC25A4	-1070
GPR39	-1035
GPC1	-1028
H2AZ2	-1025
RAB7A	-1021
ATP1A2	-1013
CTNNB1	-1006
ANAPC7	-994
PTK2	-965
ST3GAL2	-942
TFDP1	-937
B3GLCT	-915
PRDX1	-900
MYH9	-899
OMD	-898
ATP6V1H	-876
DLL4	-862
CRK	-859
DYNLL2	-826
EZH2	-801
FOXO3	-793
SLC22A5	-789
STAT3	-775
PPP2CA	-765
TPST1	-761
POLA2	-755
SEM1	-739
LIG1	-725
THSD1	-724
P2RY11	-710
STAT5B	-662
GRB2	-640
PSME1	-634
IGHV3-48	-616
IGKV1-16	-593
ELMO1	-573
WIPF3	-570
PSMA2	-550
RPS25	-545
CCNK	-540
STAM	-473
ADRB1	-453
EIF2AK3	-445
RBPJ	-418
GP1BA	-403
SLC7A7	-400
RPL21	-383
ERLIN2	-369
SRD5A3	-364
POLR2B	-362
PSMD11	-353
PSMB8	-350
KAT2A	-337
RPS3A	-334
MAP1LC3B	-329
PDPK1	-326
RCOR1	-319
PTGER2	-310
NCK1	-304
RPS13	-295
GTF2E1	-282
C1QBP	-273
GFPT1	-256
ADORA2A	-251
ADAMTS5	-249
GTF2H2	-233
MMAB	-209
PPP2R5B	-200
SMAD2	-198
RPSA	-148
FDX1	-138
SLC6A2	-113
H2AZ1	-107
GYG1	-78
NUP155	-51
ALG13	-46
NPM1	-27
JAK1	-26
POMGNT1	-24
FZD4	25
ADRB3	43
TBP	58
IDH1	67
RAF1	72
GLB1	88
RBP4	127
NOTCH3	136
UBAP1	138
ADAMTSL3	149
HCK	150
MMUT	157
MSH6	180
RNF213	223
WDR48	227
SHC1	228
TXN	237
HEY1	238
NEIL1	258
CAMK2G	277
TCEA1	285
GGCX	296
NUP42	299
ADCY2	328
PIK3R4	371
HDAC8	376
PTGDR	429
CD9	437
BANF1	440
POLA1	442
YWHAB	461
ERLEC1	481
VTA1	485
MCCC1	511
FNTA	525
DNMT3B	567
TRAK1	569
HNRNPK	570
ADCYAP1	578
MAPK1	583
VIPR2	584
DAD1	591
ACACA	604
PSME4	609
IL10	616
TAF1	629
IQGAP1	633
THSD4	634
SKP1	657
IGHV3-23	658
SLC24A4	665
GBE1	666
TPM3	694
TAF2	703
ADAMTS15	705
OGN	706
GNAI3	727
GATAD2B	739
BRCA1	754
FGF2	790
NUP205	808
KPNA4	834
GPC4	836
WIPF2	869
ADAMTS8	876
NFKB2	892
RMI2	894
CCND1	915
RPIA	918
SLC36A2	985
ANAPC4	1002
ADAMTS3	1003
E2F2	1064
VPS4B	1107
DAG1	1118
STAT2	1146
FUT8	1194
RPS7	1197
RAMP3	1215
NOTCH1	1228
FOXO1	1230
ANAPC1	1233
CBLL1	1245
RPS27L	1251
CCR5	1259
RPL22	1273
CYP2U1	1285
MAP2K1	1296
RPL24	1297
IFNGR1	1319
NUP210	1376
THSD7B	1384
DERL2	1390
MLH1	1393
EML4	1411
GCLC	1414
ADCYAP1R1	1464
XRCC5	1475
ESR2	1509
TAF9B	1536
ITGB1	1539
FGFR4	1543
MUC3A	1559
ELOC	1560
NUP153	1582
NCBP2	1609
PDZD3	1615
PSMA6	1616
SLC37A4	1623
DYNC1LI2	1641
HEPH	1653
NUP160	1654
ANAPC16	1658
APH1B	1671
GNB3	1692
HDAC1	1704
PSMA3	1706
MYO18A	1710
DNA2	1717
KLB	1731
AVP	1752
TAF3	1753
SDC4	1761
FKBP1A	1764
RBBP4	1776
ADM	1777
CSNK1A1	1813
VCL	1827
CNTRL	1832
MAP2K4	1833
FGF1	1850
PSMC6	1856
SFPQ	1882
KCNJ11	1893
ARPC3	1908
NFKBIA	1910
PRDX2	1934
P2RX7	1938
SLC3A1	1944
ALG14	1954
PPP2R5C	1957
CD86	1982
CDK5	2009
SYT2	2020
CDK7	2033
TLR4	2073
FXR1	2076
GYS1	2096
NFE2L2	2107
TGFBR1	2130
NOTCH4	2146
CCNE1	2155
MMADHC	2158
DPEP2	2161
IFNAR1	2188
FCGR2A	2194
TAF4B	2228
MMACHC	2254
DNMT3A	2286
PRKX	2291
CYP2R1	2298
RAD51AP1	2299
TAF7	2320
NUP54	2334
CYFIP2	2361
GNG5	2366
GTF2A2	2369
MAPK14	2383
TXNRD1	2385
MTRR	2393
EED	2399
CDK8	2400
GNB5	2405
ST3GAL1	2406
APC	2414
CORO1A	2417
GTF2H1	2425
FGF9	2454
ADCY1	2469
CFTR	2470
ANAPC15	2487
SV2B	2495
PPM1B	2529
GYS2	2540
CRBN	2541
CHMP5	2563
HSPA1A	2615
NUP35	2637
GPC2	2638
RFT1	2645
VPS37A	2717
AGK	2744
ADCY4	2789
SLC40A1	2790
GTF2H5	2842
GNG12	2843
CDC42	2858
B4GALT1	2878
RAMP1	2880
AGGF1	2903
VHL	2927
CUL3	2930
NCKAP1	2931
SMAD4	2951
TPM4	2953
PTPN11	2955
IRS1	2964
CNKSR2	2966
DYNC1I1	2990
TAF11	3077
BIRC6	3082
CP	3083
TGFA	3087
ABCC6	3104
ATP1B2	3109
SRPK2	3115
DKK2	3139
CANX	3141
RAD51C	3146
PPP2R5A	3154
PSMD5	3165
PIK3C3	3169
WAS	3173
FGF17	3186
CCNH	3223
MTR	3250
ADAM17	3261
LRRFIP1	3266
POLR2K	3276
PSME2	3291
DLL1	3292
NCBP1	3300
ATP1B3	3330
CD247	3342
ENTPD5	3398
ABCC8	3438
PDCD6IP	3442
PTPN12	3490
IRAK4	3499
HDAC2	3508
TAF12	3521
SUGT1	3539
ADAMTSL2	3557
PRKAR1B	3558
CDK5R1	3600
PRKACB	3604
CHMP4C	3607
VPS36	3620
XRCC4	3628
ABCA4	3639
RAD50	3666
GNAZ	3694
ZCRB1	3737
RPL3L	3763
FXYD7	3783
VWF	3802
SSPOP	3810
HDAC4	3822
IGKV1-33	3826
ABI1	3864
AKT3	3865
UBE2S	3867
ITPR1	3869
PTGIR	3894
RAC2	3895
C1GALT1C1	3911
CHUK	3917
GALNT1	3945
IL1R1	3952
SUDS3	3953
DNAJC3	3962
TNKS	3975
FRS2	3982
PPFIBP1	3989
ROCK2	3994
HRH2	3995
HEY2	4001
FGF8	4005
MYO10	4030
GTF2H3	4041
IL6R	4042
DHH	4048
SCT	4051
GNGT2	4058
PSMA4	4076
PIK3AP1	4079
TUSC3	4094
CNKSR1	4103
SLC35A1	4115
FZD5	4120
DYNC1LI1	4123
MSH2	4124
CAMK2B	4151
CDKN1B	4182
PDGFA	4223
SLC26A2	4252
PSMB9	4260
ALG11	4266
GPR27	4289
TRIM24	4307
ENTPD1	4333
GTF2B	4364
TAF5	4377
RAP1B	4389
LMBRD1	4401
CAMK2A	4415
SEMA5B	4419
LHCGR	4422
GOLGA4	4425
ZBP1	4433
PRIM2	4472
ABCC9	4474
NOXA1	4495
CD8B	4510
AP1G1	4550
PSMD12	4558
PRIM1	4564
JAG1	4583
FGR	4585
SLC35D1	4597
SLCO2A1	4601
TPMT	4609
SUMO1	4613
ATP1A4	4636
PRKAR2A	4641
RAP1A	4646
H2BC5	4656
NEURL1	4659
ARPC5	4663
NDC1	4688
CCNE2	4691
MAPK8	4720
FAM131B	4723
NUP133	4739
UBE2E1	4757
MRE11	4776
VAV3	4780
PPP2R1B	4784
DUSP10	4822
PGK1	4836
CYP19A1	4839
LIG4	4840
PPP1CC	4852
ABI2	4856
CBL	4864
ACTR3	4876
NAPEPLD	4910
NBN	4936
VPS37B	4937
NUP107	4939
RNGTT	4943
GRSF1	4944
SOS1	4952
NUS1	4959
WIPF1	4978
C1GALT1	5025
SLC9A6	5052
SLC33A1	5061
CTNND1	5064
PGM1	5076
RANBP2	5097
ALG9	5106
WNT5A	5108
PIK3CA	5148
PLCG2	5152
CD28	5157
CD36	5193
MAN2A1	5224
FBXW7	5253
CYP1B1	5259
PAK2	5269
CALM1	5275
MAP2K6	5310
ACTR2	5314
MDM2	5328
TBL1XR1	5336
TLR3	5344
STRN	5394
ALG8	5449
NF1	5468
GCC2	5478
SHOC2	5488
GCLM	5491
NEURL1B	5529
S100A8	5539
DUSP8	5560
CAMK2D	5590
ABCA1	5607
S1PR1	5621
GNS	5625
HMGB1	5663
GNG10	5674
CREB1	5680
PPP1R3C	5705
NUP37	5735
PTGES3	5736
NR3C1	5752
KPNA1	5759
PTEN	5760
ABCB11	5813
ROCK1	5817
TLR6	5830
NUP50	5855
PRKAR1A	5856
ATP1B1	5857
CHMP2B	5877
THSD7A	5903
VIP	5910
F8	5952
REST	5971
HES1	5974
BARD1	6030
WRN	6061
SEH1L	6077
HEYL	6092
ITPR2	6099
FAM114A2	6101
PPP2R5E	6103
WASL	6108
CCNT2	6121
FGFR1OP2	6147
BRAF	6148
ARID4B	6174
S100A9	6198
JAK3	6200
GIPR	6230
EIF2AK2	6233
KLKB1	6254
PARP8	6264
NOS2	6271
NRG4	6333
DPM1	6362
TNKS2	6363
RPL9	6370
FCGR3A	6371
ADRB2	6428
E2F3	6435
TRIP11	6446
GSK3B	6450
STAM2	6459
SPRED1	6462
KPNA3	6465
H2BC4	6513
DDX5	6525
KIF5B	6552
CDC27	6566
H3-3A	6579
KRAS	6593
RPL22L1	6595
RAB5A	6603
SEL1L	6611
ETV6	6619
CASP8	6627
CSF2RB	6665
IFNAR2	6667
EPS15	6673
SLC12A6	6707
QKI	6728
UBE2D1	6734
ST6GALNAC2	6754
SLC1A1	6769
NLRP3	6794
NRAS	6815
CEBPD	6830
ABCG8	6876
RPL36A	6879
STAT1	6884
PIK3R3	6894
CEBPB	6914
PPP1CB	6943
AP1S2	7001
SKP2	7003
BAG4	7004
TLR7	7011
PSIP1	7030
PARP14	7049
CYSLTR1	7068
PIK3CD	7072
PIK3CB	7088
CASP1	7103
SYT1	7118
ZMYM2	7134
CEP43	7147
HDAC9	7170
CYP7B1	7199
ARID4A	7233
MMAA	7252
XPO1	7330
SLC26A4	7335
KL	7437
ADAMTS9	7443
CD3G	7496
FZD8	7503
ATM	7528
SLC35A3	7541
SLC4A4	7557
CDK6	7579
CRHR2	7581
GTF2A1	7584
TAF13	7602
BCL2L11	7604
MAGT1	7627
THBS1	7643
TBK1	7671
PARP9	7678
RAD51B	7690
SBSPON	7693
CDH1	7696
BLM	7698
CAMK4	7701
CCNC	7737
ADAM10	7778
SOD2	7796
YES1	7797
LMO7	7850
SAP30	7866
PIM1	7873
TLR1	7884
B2M	7903
SRPK1	7919
KDR	7920
SUZ12	7927
AKAP9	7959
LMNB1	7977
ERBIN	8006
ERBB4	8024
MEFV	8037
FGF7	8041
BRCA2	8055
MET	8067
ST6GALNAC3	8094
GNG11	8107
CHSY1	8158
LYN	8170
ALG6	8225
BRIP1	8237
BIN2	8238
ZC3HAV1	8248
CCNT1	8260
CALCRL	8275
ATRX	8277
JAK2	8287
H2AC18	8329
DUSP6	8350
EGF	8356
RB1	8392
MIB1	8398
RMI1	8421
CXCR4	8427
LRP6	8467
KITLG	8497
HGF	8513
GNB4	8519
LY96	8522
AP1S3	8535
KAT2B	8536
ACE2	8539
PLK2	8574
ERBB3	8618
KDM7A	8628
GAB1	8650
CDK2	8654
SEMA5A	8696
XRCC2	8717
MGAT4A	8724
JUNB	8755
KPNA5	8768
TSHR	8770
ITGA4	8771
NUP58	8794
BCL2A1	8812
NR4A1	8818
H2BC21	8851
KSR2	8900
FGF23	8908
MGAT4C	8924
FZD6	8948
SLC22A12	8953
SLC12A1	8954
TLR2	8970
H2AC6	8988
HBEGF	9018
RICTOR	9051
JUN	9070
NRG1	9081
CUL5	9127
MYC	9159
GALNT3	9192
PTGER4	9214
CDKN1A	9222
FCGR1A	9248
ADAMTS18	9324
BCL11A	9358
AREG	9397
IL1B	9408
AVPR1A	9413
ADAMTS1	9426
IL6	9444
ADAMTS4	9450

---

Response of EIF2AK4 (GCN2) to amino acid deficiency

Response of EIF2AK4 (GCN2) to amino acid deficiency

	1073
set	Response of EIF2AK4 (GCN2) to amino acid deficiency
setSize	100
pANOVA	5.99e-14
s.dist	-0.434
p.adjustANOVA	2.56e-12

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS4X	-9157
RPLP2	-8715
RPL3	-8564
RPL23	-8406
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
RPL13	-7472
RPS18	-7468
RPL7A	-7394
RPS16	-7390

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS4X	-9157
RPLP2	-8715
RPL3	-8564
RPL23	-8406
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
RPL13	-7472
RPS18	-7468
RPL7A	-7394
RPS16	-7390
RPS10	-7354
RPL26	-7340
RPL10A	-7253
RPL30	-7217
RPS11	-7138
RPL4	-7127
FAU	-7067
RPL13A	-7019
EIF2AK4	-6913
RPS17	-6903
RPS15	-6758
RPL29	-6731
RPL36AL	-6668
RPS20	-6537
RPL38	-6495
RPL12	-6483
RPLP0	-6397
RPL10	-6333
RPL8	-6300
RPL5	-6221
RPL37A	-6135
RPL27A	-6113
RPS2	-5959
RPS8	-5958
RPS21	-5899
RPL11	-5867
RPS27	-5866
RPLP1	-5846
RPS6	-5819
DDIT3	-5758
RPL17	-5749
RPL15	-5698
RPL32	-5598
RPL41	-5397
RPL18	-5360
TRIB3	-5342
RPL23A	-5246
RPL34	-5148
RPL7	-5057
RPL18A	-5015
RPL6	-4942
RPS23	-4940
RPS19	-4848
RPS3	-4842
RPL14	-4555
RPS15A	-4165
RPL27	-3935
RPL35	-3792
RPL39L	-3699
GCN1	-3595
RPL39	-3539
EIF2S2	-3286
RPS9	-3253
RPS24	-3138
RPS29	-3082
RPS27A	-2058
RPL35A	-1829
ATF4	-1387
RPS4Y1	-1198
RPS25	-545
RPL21	-383
RPS3A	-334
RPS13	-295
RPSA	-148
EIF2S3	-66
CEBPG	329
IMPACT	880
RPS7	1197
RPS27L	1251
RPL22	1273
RPL24	1297
ASNS	3352
RPL3L	3763
EIF2S1	4031
RPL9	6370
RPL22L1	6595
RPL36A	6879
CEBPB	6914
ATF2	7424
ATF3	9275

---

Regulation of actin dynamics for phagocytic cup formation

Regulation of actin dynamics for phagocytic cup formation

	1042
set	Regulation of actin dynamics for phagocytic cup formation
setSize	109
pANOVA	1.47e-13
s.dist	-0.41
p.adjustANOVA	6.1e-12

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
IGHG2	-9010

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
IGHG2	-9010
IGHV3-30	-8906
IGHG3	-8775
ABL1	-8744
IGLV1-47	-8713
IGLV3-21	-8651
IGKV3-15	-8522
ACTG1	-8451
IGHG4	-8417
IGKV3-20	-8400
IGLV2-23	-8106
IGLV3-19	-7984
BAIAP2	-7819
NCKIPSD	-7618
WASF1	-7486
IGHV4-59	-7466
WASF2	-7299
ACTB	-7187
LIMK1	-7164
ARPC1A	-7142
IGKV2-30	-7018
MYO9B	-6996
ARPC1B	-6869
NF2	-6823
IGKV4-1	-6785
BRK1	-6636
IGLV6-57	-6578
MYO1C	-6410
DOCK1	-6096
IGLV1-40	-5992
MAPK3	-5987
IGHV4-39	-5760
IGKV2D-28	-5697
CFL1	-5571
HSP90AB1	-5567
IGHV1-2	-5528
IGHG1	-5275
IGLV1-51	-5257
IGKC	-5210
ARPC2	-5195
MYO5A	-4904
IGKV1D-39	-4621
IGKV1-12	-4498
WASF3	-4071
VAV1	-3953
ARPC4	-3888
BTK	-3657
IGHV4-34	-3644
NCKAP1L	-3307
CYFIP1	-3125
RAC1	-2805
HSP90AA1	-2745
ELMO2	-2473
MYH2	-1794
VAV2	-1647
IGLV1-44	-1280
SYK	-1210
PTK2	-965
MYH9	-899
CRK	-859
GRB2	-640
IGHV3-48	-616
IGKV1-16	-593
ELMO1	-573
WIPF3	-570
NCK1	-304
MAPK1	583
IGHV3-23	658
PAK1	839
WIPF2	869
ARPC3	1908
FCGR2A	2194
CYFIP2	2361
CDC42	2858
NCKAP1	2931
WAS	3173
CD247	3342
IGKV1-33	3826
ABI1	3864
MYO10	4030
ARPC5	4663
VAV3	4780
ABI2	4856
ACTR3	4876
WIPF1	4978
ACTR2	5314
WASL	6108
FCGR3A	6371
CD3G	7496
FCGR1A	9248

---

Influenza Infection

Influenza Infection

	556
set	Influenza Infection
setSize	154
pANOVA	1.85e-13
s.dist	-0.344
p.adjustANOVA	7.46e-12

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SLC25A6	-9520
GTF2F1	-9321
RPS4X	-9157
AAAS	-9006
RPLP2	-8715
RPL3	-8564
SEC13	-8457
RPL23	-8406
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
RPL26L1	-7694
NUP188	-7684
POLR2G	-7651

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SLC25A6	-9520
GTF2F1	-9321
RPS4X	-9157
AAAS	-9006
RPLP2	-8715
RPL3	-8564
SEC13	-8457
RPL23	-8406
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
RPL37	-7930
RPS26	-7908
RPL31	-7842
RPL26L1	-7694
NUP188	-7684
POLR2G	-7651
UBA52	-7643
RPS5	-7633
RPL13	-7472
RPS18	-7468
POLR2F	-7453
RPL7A	-7394
RPS16	-7390
RPS10	-7354
NUP85	-7351
RPL26	-7340
RPL10A	-7253
RPL30	-7217
RPS11	-7138
RPL4	-7127
FAU	-7067
RPL13A	-7019
POLR2H	-6957
RPS17	-6903
CALR	-6854
RPS15	-6758
RPL29	-6731
RPL36AL	-6668
RPS20	-6537
RPL38	-6495
RPL12	-6483
RPLP0	-6397
RPL10	-6333
RPL8	-6300
ISG15	-6233
POM121	-6225
RPL5	-6221
RPL37A	-6135
RPL27A	-6113
RPS2	-5959
RPS8	-5958
RPS21	-5899
RPL11	-5867
RPS27	-5866
RPLP1	-5846
RPS6	-5819
RPL17	-5749
RPL15	-5698
RPL32	-5598
RPL41	-5397
RPL18	-5360
PABPN1	-5294
RPL23A	-5246
KPNA2	-5200
RPL34	-5148
RPL7	-5057
CLTA	-5023
RPL18A	-5015
RPL6	-4942
RPS23	-4940
RAN	-4882
RPS19	-4848
RPS3	-4842
POLR2I	-4811
POLR2C	-4802
NUP62	-4588
RPL14	-4555
TPR	-4504
POLR2E	-4389
IPO5	-4347
NUP214	-4176
RPS15A	-4165
RPL27	-3935
RAE1	-3807
RPL35	-3792
TGFB1	-3765
RPL39L	-3699
NUP88	-3689
POM121C	-3677
RPL39	-3539
NUP98	-3400
POLR2J	-3355
CPSF4	-3300
RPS9	-3253
PARP1	-3200
CLTC	-3186
NUP93	-3163
RPS24	-3138
RPS29	-3082
NUP43	-2946
HSP90AA1	-2745
KPNB1	-2542
POLR2L	-2358
RPS27A	-2058
GTF2F2	-2047
RPL35A	-1829
POLR2D	-1531
POLR2A	-1215
RPS4Y1	-1198
RPS25	-545
RPL21	-383
POLR2B	-362
RPS3A	-334
RPS13	-295
RPSA	-148
NUP155	-51
NUP42	299
NUP205	808
KPNA4	834
RPS7	1197
RPS27L	1251
RPL22	1273
RPL24	1297
NUP210	1376
NUP153	1582
NUP160	1654
NUP54	2334
HSPA1A	2615
NUP35	2637
CANX	3141
POLR2K	3276
RPL3L	3763
DNAJC3	3962
NDC1	4688
NUP133	4739
NUP107	4939
GRSF1	4944
RANBP2	5097
NUP37	5735
KPNA1	5759
NUP50	5855
SEH1L	6077
EIF2AK2	6233
RPL9	6370
KPNA3	6465
RPL22L1	6595
RPL36A	6879
XPO1	7330
KPNA5	8768
NUP58	8794

---

FCGR activation

FCGR activation

	382
set	FCGR activation
setSize	60
pANOVA	6.05e-13
s.dist	-0.537
p.adjustANOVA	2.38e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
IGHG2	-9010

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
IGHG2	-9010
IGHV3-30	-8906
SRC	-8900
IGHG3	-8775
IGLV1-47	-8713
IGLV3-21	-8651
IGKV3-15	-8522
IGHG4	-8417
IGKV3-20	-8400
IGLV2-23	-8106
IGLV3-19	-7984
FYN	-7874
IGHV4-59	-7466
IGKV2-30	-7018
IGKV4-1	-6785
IGLV6-57	-6578
IGLV1-40	-5992
IGHV4-39	-5760
IGKV2D-28	-5697
IGHV1-2	-5528
IGHG1	-5275
IGLV1-51	-5257
IGKC	-5210
IGKV1D-39	-4621
IGKV1-12	-4498
IGHV4-34	-3644
IGLV1-44	-1280
SYK	-1210
IGHV3-48	-616
IGKV1-16	-593
HCK	150
IGHV3-23	658
FCGR2A	2194
CD247	3342
IGKV1-33	3826
FGR	4585
FCGR3A	6371
CD3G	7496
YES1	7797
LYN	8170
FCGR1A	9248

---

Cellular response to starvation

Cellular response to starvation

	178
set	Cellular response to starvation
setSize	151
pANOVA	6.52e-13
s.dist	-0.339
p.adjustANOVA	2.5e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS4X	-9157
RPLP2	-8715
RPL3	-8564
SEC13	-8457
RPL23	-8406
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
WDR24	-7980
RPL37	-7930
RPS26	-7908
RPL31	-7842
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
FLCN	-7611
RPL13	-7472

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS4X	-9157
RPLP2	-8715
RPL3	-8564
SEC13	-8457
RPL23	-8406
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
WDR24	-7980
RPL37	-7930
RPS26	-7908
RPL31	-7842
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
FLCN	-7611
RPL13	-7472
RPS18	-7468
ITFG2	-7436
RPL7A	-7394
RPS16	-7390
RPS10	-7354
RPL26	-7340
NPRL3	-7295
RPL10A	-7253
RPL30	-7217
RPS11	-7138
RPL4	-7127
FAU	-7067
RPL13A	-7019
EIF2AK4	-6913
RPS17	-6903
RPS15	-6758
RPL29	-6731
RPL36AL	-6668
LAMTOR4	-6648
RPS20	-6537
MLST8	-6519
RPL38	-6495
RPL12	-6483
RPLP0	-6397
RPL10	-6333
LAMTOR2	-6311
RPL8	-6300
RPL5	-6221
RPL37A	-6135
RPL27A	-6113
WDR59	-6054
ATP6V0B	-5977
RPS2	-5959
RPS8	-5958
ATP6V0D1	-5934
RPS21	-5899
RPL11	-5867
RPS27	-5866
RPLP1	-5846
RPS6	-5819
DDIT3	-5758
RPL17	-5749
RPL15	-5698
RPL32	-5598
RPL41	-5397
RPL18	-5360
TRIB3	-5342
RPL23A	-5246
RRAGB	-5194
RPL34	-5148
RPL7	-5057
TCIRG1	-5017
RPL18A	-5015
RPL6	-4942
RPS23	-4940
RPS19	-4848
RPS3	-4842
LAMTOR1	-4755
ATP6V1F	-4696
RPL14	-4555
ATP6V1B1	-4396
MTOR	-4239
ATP6V1E1	-4236
RPS15A	-4165
RPL27	-3935
KPTN	-3800
RPL35	-3792
RPL39L	-3699
GCN1	-3595
RPL39	-3539
RRAGA	-3479
RPTOR	-3421
ATP6V0C	-3416
ATP6V0E1	-3412
SESN2	-3316
EIF2S2	-3286
RPS9	-3253
DEPDC5	-3238
RPS24	-3138
RPS29	-3082
NPRL2	-2310
RRAGC	-2106
ATP6V1E2	-2095
RPS27A	-2058
RPL35A	-1829
ATF4	-1387
LAMTOR5	-1245
RPS4Y1	-1198
ATP6V1D	-1140
SZT2	-879
ATP6V1H	-876
SH3BP4	-696
RPS25	-545
RPL21	-383
RPS3A	-334
RPS13	-295
RPSA	-148
EIF2S3	-66
ATP6V0E2	-60
ATP6V1C1	38
CEBPG	329
SESN1	726
IMPACT	880
ATP6V1G1	1079
RPS7	1197
RPS27L	1251
RPL22	1273
RPL24	1297
RHEB	1848
RRAGD	1883
ATP6V1G2	1889
MIOS	2598
LAMTOR3	3279
ASNS	3352
RPL3L	3763
EIF2S1	4031
ATP6V1B2	4684
FNIP1	5034
FNIP2	5636
SEH1L	6077
ATP6V1C2	6141
RPL9	6370
RPL22L1	6595
ATP6V1A	6744
SLC38A9	6874
RPL36A	6879
CEBPB	6914
ATF2	7424
ATP6V0D2	7571
BMT2	7603
ATF3	9275

---

Role of LAT2/NTAL/LAB on calcium mobilization

Role of LAT2/NTAL/LAB on calcium mobilization

	1081
set	Role of LAT2/NTAL/LAB on calcium mobilization
setSize	57
pANOVA	7.87e-13
s.dist	-0.548
p.adjustANOVA	2.94e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
IGHV3-30	-8906

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
IGHV3-30	-8906
IGLV1-47	-8713
IGLV3-21	-8651
IGKV3-15	-8522
IGKV3-20	-8400
IGLV2-23	-8106
IGLV3-19	-7984
FYN	-7874
IGHV4-59	-7466
IGKV2-30	-7018
IGKV4-1	-6785
PIK3R2	-6618
IGLV6-57	-6578
IGLV1-40	-5992
IGHV4-39	-5760
IGKV2D-28	-5697
IGHV1-2	-5528
IGLV1-51	-5257
IGKC	-5210
GAB2	-4727
IGKV1D-39	-4621
IGKV1-12	-4498
IGHV4-34	-3644
PIK3R1	-2575
IGLV1-44	-1280
SYK	-1210
GRB2	-640
IGHV3-48	-616
IGKV1-16	-593
PDPK1	-326
SHC1	228
IGHV3-23	658
IGKV1-33	3826
SOS1	4952
PIK3CA	5148
PIK3CB	7088
LAT2	7632
LYN	8170

---

FCGR3A-mediated phagocytosis

FCGR3A-mediated phagocytosis

	384
set	FCGR3A-mediated phagocytosis
setSize	107
pANOVA	1.12e-12
s.dist	-0.398
p.adjustANOVA	3.87e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
IGHG2	-9010

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
IGHG2	-9010
IGHV3-30	-8906
SRC	-8900
IGHG3	-8775
ABL1	-8744
IGLV1-47	-8713
IGLV3-21	-8651
IGKV3-15	-8522
ACTG1	-8451
IGHG4	-8417
IGKV3-20	-8400
IGLV2-23	-8106
IGLV3-19	-7984
FYN	-7874
BAIAP2	-7819
NCKIPSD	-7618
WASF1	-7486
IGHV4-59	-7466
WASF2	-7299
ACTB	-7187
ARPC1A	-7142
IGKV2-30	-7018
MYO9B	-6996
ARPC1B	-6869
IGKV4-1	-6785
BRK1	-6636
IGLV6-57	-6578
MYO1C	-6410
DOCK1	-6096
IGLV1-40	-5992
MAPK3	-5987
IGHV4-39	-5760
IGKV2D-28	-5697
IGHV1-2	-5528
IGHG1	-5275
IGLV1-51	-5257
IGKC	-5210
ARPC2	-5195
MYO5A	-4904
IGKV1D-39	-4621
IGKV1-12	-4498
WASF3	-4071
VAV1	-3953
ARPC4	-3888
BTK	-3657
IGHV4-34	-3644
NCKAP1L	-3307
CYFIP1	-3125
RAC1	-2805
ELMO2	-2473
MYH2	-1794
VAV2	-1647
IGLV1-44	-1280
SYK	-1210
PTK2	-965
MYH9	-899
CRK	-859
GRB2	-640
IGHV3-48	-616
IGKV1-16	-593
ELMO1	-573
WIPF3	-570
NCK1	-304
HCK	150
MAPK1	583
IGHV3-23	658
WIPF2	869
ARPC3	1908
CYFIP2	2361
CDC42	2858
NCKAP1	2931
WAS	3173
CD247	3342
IGKV1-33	3826
ABI1	3864
MYO10	4030
FGR	4585
ARPC5	4663
VAV3	4780
ABI2	4856
ACTR3	4876
WIPF1	4978
ACTR2	5314
WASL	6108
FCGR3A	6371
CD3G	7496
YES1	7797
LYN	8170

---

Leishmania phagocytosis

Leishmania phagocytosis

	631
set	Leishmania phagocytosis
setSize	107
pANOVA	1.12e-12
s.dist	-0.398
p.adjustANOVA	3.87e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
IGHG2	-9010

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
IGHG2	-9010
IGHV3-30	-8906
SRC	-8900
IGHG3	-8775
ABL1	-8744
IGLV1-47	-8713
IGLV3-21	-8651
IGKV3-15	-8522
ACTG1	-8451
IGHG4	-8417
IGKV3-20	-8400
IGLV2-23	-8106
IGLV3-19	-7984
FYN	-7874
BAIAP2	-7819
NCKIPSD	-7618
WASF1	-7486
IGHV4-59	-7466
WASF2	-7299
ACTB	-7187
ARPC1A	-7142
IGKV2-30	-7018
MYO9B	-6996
ARPC1B	-6869
IGKV4-1	-6785
BRK1	-6636
IGLV6-57	-6578
MYO1C	-6410
DOCK1	-6096
IGLV1-40	-5992
MAPK3	-5987
IGHV4-39	-5760
IGKV2D-28	-5697
IGHV1-2	-5528
IGHG1	-5275
IGLV1-51	-5257
IGKC	-5210
ARPC2	-5195
MYO5A	-4904
IGKV1D-39	-4621
IGKV1-12	-4498
WASF3	-4071
VAV1	-3953
ARPC4	-3888
BTK	-3657
IGHV4-34	-3644
NCKAP1L	-3307
CYFIP1	-3125
RAC1	-2805
ELMO2	-2473
MYH2	-1794
VAV2	-1647
IGLV1-44	-1280
SYK	-1210
PTK2	-965
MYH9	-899
CRK	-859
GRB2	-640
IGHV3-48	-616
IGKV1-16	-593
ELMO1	-573
WIPF3	-570
NCK1	-304
HCK	150
MAPK1	583
IGHV3-23	658
WIPF2	869
ARPC3	1908
CYFIP2	2361
CDC42	2858
NCKAP1	2931
WAS	3173
CD247	3342
IGKV1-33	3826
ABI1	3864
MYO10	4030
FGR	4585
ARPC5	4663
VAV3	4780
ABI2	4856
ACTR3	4876
WIPF1	4978
ACTR2	5314
WASL	6108
FCGR3A	6371
CD3G	7496
YES1	7797
LYN	8170

---

Parasite infection

Parasite infection

	840
set	Parasite infection
setSize	107
pANOVA	1.12e-12
s.dist	-0.398
p.adjustANOVA	3.87e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
IGHG2	-9010

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
IGHG2	-9010
IGHV3-30	-8906
SRC	-8900
IGHG3	-8775
ABL1	-8744
IGLV1-47	-8713
IGLV3-21	-8651
IGKV3-15	-8522
ACTG1	-8451
IGHG4	-8417
IGKV3-20	-8400
IGLV2-23	-8106
IGLV3-19	-7984
FYN	-7874
BAIAP2	-7819
NCKIPSD	-7618
WASF1	-7486
IGHV4-59	-7466
WASF2	-7299
ACTB	-7187
ARPC1A	-7142
IGKV2-30	-7018
MYO9B	-6996
ARPC1B	-6869
IGKV4-1	-6785
BRK1	-6636
IGLV6-57	-6578
MYO1C	-6410
DOCK1	-6096
IGLV1-40	-5992
MAPK3	-5987
IGHV4-39	-5760
IGKV2D-28	-5697
IGHV1-2	-5528
IGHG1	-5275
IGLV1-51	-5257
IGKC	-5210
ARPC2	-5195
MYO5A	-4904
IGKV1D-39	-4621
IGKV1-12	-4498
WASF3	-4071
VAV1	-3953
ARPC4	-3888
BTK	-3657
IGHV4-34	-3644
NCKAP1L	-3307
CYFIP1	-3125
RAC1	-2805
ELMO2	-2473
MYH2	-1794
VAV2	-1647
IGLV1-44	-1280
SYK	-1210
PTK2	-965
MYH9	-899
CRK	-859
GRB2	-640
IGHV3-48	-616
IGKV1-16	-593
ELMO1	-573
WIPF3	-570
NCK1	-304
HCK	150
MAPK1	583
IGHV3-23	658
WIPF2	869
ARPC3	1908
CYFIP2	2361
CDC42	2858
NCKAP1	2931
WAS	3173
CD247	3342
IGKV1-33	3826
ABI1	3864
MYO10	4030
FGR	4585
ARPC5	4663
VAV3	4780
ABI2	4856
ACTR3	4876
WIPF1	4978
ACTR2	5314
WASL	6108
FCGR3A	6371
CD3G	7496
YES1	7797
LYN	8170

---

Signaling by ROBO receptors

Signaling by ROBO receptors

	1216
set	Signaling by ROBO receptors
setSize	206
pANOVA	1.28e-12
s.dist	-0.287
p.adjustANOVA	4.34e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ROBO3	-9174
RPS4X	-9157
SRC	-8900
NTN1	-8863
CASC3	-8770
ABL1	-8744
RPLP2	-8715
RPL3	-8564
RPL23	-8406
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
EVL	-8025
RPL37	-7930
RPS26	-7908
RPL31	-7842
PABPC1	-7807

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ROBO3	-9174
RPS4X	-9157
SRC	-8900
NTN1	-8863
CASC3	-8770
ABL1	-8744
RPLP2	-8715
RPL3	-8564
RPL23	-8406
RPS14	-8278
RPS12	-8256
RPL36	-8166
RPL19	-8133
RPS28	-8128
RPL28	-8031
EVL	-8025
RPL37	-7930
RPS26	-7908
RPL31	-7842
PABPC1	-7807
RPL26L1	-7694
UBA52	-7643
RPS5	-7633
PSMA7	-7617
SRGAP2	-7607
PSMB7	-7580
PSMC3	-7538
RPL13	-7472
RPS18	-7468
RPL7A	-7394
RPS16	-7390
RPS10	-7354
RPL26	-7340
RPL10A	-7253
RPL30	-7217
RPS11	-7138
PSMD4	-7134
RPL4	-7127
SLIT3	-7117
FAU	-7067
RPL13A	-7019
MYO9B	-6996
PSMC5	-6942
RPS17	-6903
RPS15	-6758
RPL29	-6731
PSMD8	-6703
RPL36AL	-6668
ZSWIM8	-6567
RPS20	-6537
RPL38	-6495
RPL12	-6483
PSMB4	-6417
RPLP0	-6397
RPL10	-6333
RPL8	-6300
RPL5	-6221
RPL37A	-6135
RPL27A	-6113
LDB1	-5991
RPS2	-5959
RPS8	-5958
RPS21	-5899
RPL11	-5867
RPS27	-5866
RPLP1	-5846
RPS6	-5819
PSMD9	-5765
RPL17	-5749
RPL15	-5698
RPL32	-5598
ROBO1	-5521
PSMF1	-5494
RPL41	-5397
RPL18	-5360
PSMB3	-5327
ELOB	-5284
MAGOH	-5252
RPL23A	-5246
PSMD3	-5235
PSMB1	-5182
PFN1	-5171
RPL34	-5148
PSMD7	-5070
RPL7	-5057
RPL18A	-5015
PSMD14	-4951
PSMB10	-4948
RPL6	-4942
RPS23	-4940
NCK2	-4919
PSMC2	-4880
PSMB6	-4849
RPS19	-4848
RPS3	-4842
PSMD2	-4715
PSMA1	-4587
RPL14	-4555
PSMA5	-4364
PSMD10	-4338
PSMD1	-4278
RPS15A	-4165
RPL27	-3935
RNPS1	-3887
RPL35	-3792
RPL39L	-3699
GSPT2	-3673
RBX1	-3643
UPF3A	-3628
CAP1	-3602
RPL39	-3539
PSMC4	-3510
PAK6	-3311
RPS9	-3253
PAK4	-3251
PSMB2	-3187
RPS24	-3138
RPS29	-3082
EIF4G1	-2994
RHOA	-2880
UBB	-2810
RAC1	-2805
UBC	-2608
PSMD6	-2563
ROBO2	-2493
PSMB5	-2492
PSMD13	-2447
ARHGAP39	-2151
RPS27A	-2058
PRKACA	-1995
RPL35A	-1829
PSME3	-1691
PSMC1	-1275
RPS4Y1	-1198
CLASP1	-1097
GPC1	-1028
SLIT2	-819
SEM1	-739
PSME1	-634
CUL2	-617
RBM8A	-558
PSMA2	-550
RPS25	-545
RPL21	-383
PSMD11	-353
PSMB8	-350
RPS3A	-334
NCK1	-304
RPS13	-295
EIF4A3	-261
RPSA	-148
PSME4	609
PFN2	642
PAK1	839
NELL2	960
DAG1	1118
RPS7	1197
ETF1	1218
RPS27L	1251
RPL22	1273
RPL24	1297
CXCL12	1490
ELOC	1560
NCBP2	1609
PSMA6	1616
PSMA3	1706
VASP	1732
UPF3B	1800
PSMC6	1856
UPF2	1902
GSPT1	2097
CDC42	2858
SRGAP3	3062
ABL2	3097
PSMD5	3165
PSME2	3291
NCBP1	3300
PAK3	3532
PRKACB	3604
CAP2	3699
SLIT1	3728
RPL3L	3763
USP33	3940
PSMA4	4076
AKAP5	4212
PSMB9	4260
PPP3CB	4473
PSMD12	4558
FLRT3	4563
PRKAR2A	4641
PRKCA	4793
HOXA2	4950
SOS1	4952
ENAH	5181
PAK2	5269
NRP1	5414
LHX4	5925
SRGAP1	6005
RPL9	6370
MAGOHB	6565
RPL22L1	6595
RPL36A	6879
COL4A5	6962
SOS2	7318
CLASP2	7750
CXCR4	8427

---

Role of phospholipids in phagocytosis

Role of phospholipids in phagocytosis

	1082
set	Role of phospholipids in phagocytosis
setSize	72
pANOVA	6.63e-12
s.dist	-0.468
p.adjustANOVA	2.19e-10

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
IGHG2	-9010

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
IGHG2	-9010
IGHV3-30	-8906
IGHG3	-8775
IGLV1-47	-8713
IGLV3-21	-8651
IGKV3-15	-8522
IGHG4	-8417
IGKV3-20	-8400
IGLV2-23	-8106
IGLV3-19	-7984
IGHV4-59	-7466
PLD3	-7241
IGKV2-30	-7018
IGKV4-1	-6785
PRKCD	-6726
PIK3R2	-6618
IGLV6-57	-6578
PLD2	-6574
PLA2G6	-6181
IGLV1-40	-5992
ITPR3	-5979
IGHV4-39	-5760
IGKV2D-28	-5697
IGHV1-2	-5528
IGHG1	-5275
IGLV1-51	-5257
IGKC	-5210
IGKV1D-39	-4621
IGKV1-12	-4498
IGHV4-34	-3644
PLCG1	-3308
PIK3R1	-2575
AHCYL1	-1655
IGLV1-44	-1280
SYK	-1210
PLPP5	-985
IGHV3-48	-616
IGKV1-16	-593
IGHV3-23	658
PLD1	679
FCGR2A	2194
CD247	3342
IGKV1-33	3826
ITPR1	3869
PRKCE	4049
PIK3CA	5148
PLCG2	5152
PLD4	5520
ITPR2	6099
FCGR3A	6371
PIK3CB	7088
CD3G	7496
FCGR1A	9248

---

Fcgamma receptor (FCGR) dependent phagocytosis

Fcgamma receptor (FCGR) dependent phagocytosis

	409
set	Fcgamma receptor (FCGR) dependent phagocytosis
setSize	133
pANOVA	1.25e-11
s.dist	-0.34
p.adjustANOVA	4.03e-10

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
IGHG2	-9010

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
IGHG2	-9010
IGHV3-30	-8906
SRC	-8900
IGHG3	-8775
ABL1	-8744
IGLV1-47	-8713
IGLV3-21	-8651
IGKV3-15	-8522
ACTG1	-8451
IGHG4	-8417
IGKV3-20	-8400
IGLV2-23	-8106
IGLV3-19	-7984
FYN	-7874
BAIAP2	-7819
NCKIPSD	-7618
WASF1	-7486
IGHV4-59	-7466
WASF2	-7299
PLD3	-7241
ACTB	-7187
LIMK1	-7164
ARPC1A	-7142
IGKV2-30	-7018
MYO9B	-6996
ARPC1B	-6869
NF2	-6823
IGKV4-1	-6785
PRKCD	-6726
BRK1	-6636
PIK3R2	-6618
IGLV6-57	-6578
PLD2	-6574
MYO1C	-6410
PLA2G6	-6181
DOCK1	-6096
IGLV1-40	-5992
MAPK3	-5987
ITPR3	-5979
IGHV4-39	-5760
IGKV2D-28	-5697
CFL1	-5571
HSP90AB1	-5567
IGHV1-2	-5528
IGHG1	-5275
IGLV1-51	-5257
IGKC	-5210
ARPC2	-5195
MYO5A	-4904
IGKV1D-39	-4621
IGKV1-12	-4498
WASF3	-4071
VAV1	-3953
ARPC4	-3888
BTK	-3657
IGHV4-34	-3644
PLCG1	-3308
NCKAP1L	-3307
CYFIP1	-3125
RAC1	-2805
HSP90AA1	-2745
PIK3R1	-2575
ELMO2	-2473
MYH2	-1794
AHCYL1	-1655
VAV2	-1647
IGLV1-44	-1280
SYK	-1210
PLPP5	-985
PTK2	-965
MYH9	-899
CRK	-859
GRB2	-640
IGHV3-48	-616
IGKV1-16	-593
ELMO1	-573
WIPF3	-570
NCK1	-304
HCK	150
MAPK1	583
IGHV3-23	658
PLD1	679
PAK1	839
WIPF2	869
ARPC3	1908
FCGR2A	2194
CYFIP2	2361
CDC42	2858
NCKAP1	2931
WAS	3173
CD247	3342
IGKV1-33	3826
ABI1	3864
ITPR1	3869
MYO10	4030
PRKCE	4049
FGR	4585
ARPC5	4663
VAV3	4780
ABI2	4856
ACTR3	4876
WIPF1	4978
PIK3CA	5148
PLCG2	5152
ACTR2	5314
PLD4	5520
ITPR2	6099
WASL	6108
FCGR3A	6371
PIK3CB	7088
CD3G	7496
YES1	7797
LYN	8170
FCGR1A	9248

---

FCERI mediated NF-kB activation

FCERI mediated NF-kB activation

	381
set	FCERI mediated NF-kB activation
setSize	120
pANOVA	4.28e-11
s.dist	-0.348
p.adjustANOVA	1.35e-09

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
IGHV3-30	-8906

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
IGHV3-30	-8906
IGLV1-47	-8713
IGLV3-21	-8651
IGKV3-15	-8522
IGKV3-20	-8400
IGLV2-23	-8106
IGLV3-19	-7984
UBA52	-7643
PSMA7	-7617
PSMB7	-7580
IKBKG	-7562
PSMC3	-7538
IGHV4-59	-7466
PSMD4	-7134
IGKV2-30	-7018
PSMC5	-6942
IGKV4-1	-6785
PSMD8	-6703
IGLV6-57	-6578
TAB1	-6572
PSMB4	-6417
IGLV1-40	-5992
PSMD9	-5765
IGHV4-39	-5760
IGKV2D-28	-5697
IGHV1-2	-5528
PSMF1	-5494
PSMB3	-5327
IGLV1-51	-5257
PSMD3	-5235
CDC34	-5223
IGKC	-5210
PSMB1	-5182
PSMD7	-5070
PSMD14	-4951
PSMB10	-4948
PSMC2	-4880
PSMB6	-4849
PSMD2	-4715
IGKV1D-39	-4621
PSMA1	-4587
IGKV1-12	-4498
PSMA5	-4364
IKBKB	-4349
PSMD10	-4338
PSMD1	-4278
CUL1	-3857
BTRC	-3803
IGHV4-34	-3644
NFKB1	-3526
PSMC4	-3510
PSMB2	-3187
RELA	-3015
UBB	-2810
UBC	-2608
PSMD6	-2563
PSMB5	-2492
PSMD13	-2447
RPS27A	-2058
PSME3	-1691
IGLV1-44	-1280
PSMC1	-1275
SEM1	-739
PSME1	-634
IGHV3-48	-616
IGKV1-16	-593
PSMA2	-550
PSMD11	-353
PSMB8	-350
PDPK1	-326
UBE2V1	-132
TAB2	599
PSME4	609
SKP1	657
IGHV3-23	658
FBXW11	758
RASGRP2	1600
PSMA6	1616
PSMA3	1706
RASGRP4	1838
PSMC6	1856
NFKBIA	1910
TRAF6	2915
PSMD5	3165
CARD11	3194
PSME2	3291
UBE2D2	3489
IGKV1-33	3826
CHUK	3917
PSMA4	4076
UBE2N	4119
MAP3K7	4197
PSMB9	4260
PSMD12	4558
PRKCQ	5176
TAB3	5845
UBE2D1	6734
BCL10	7831
RASGRP1	8088
LYN	8170
MALT1	8193

---

Metabolism

Metabolism

	668
set	Metabolism
setSize	1834
pANOVA	4.45e-11
s.dist	-0.0934
p.adjustANOVA	1.38e-09

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PLA2G5	-9553
HMGCS2	-9544
LYVE1	-9510
CYP4B1	-9506
PTGES	-9463
PTGIS	-9456
CYP2S1	-9450
ALDH1A1	-9446
CBR1	-9440
GSTM1	-9437
HPGDS	-9403
ADH1C	-9399
NMRAL1	-9398
CBS	-9387
MLXIPL	-9351
NQO2	-9337
CIDEA	-9300
PRELP	-9299
PLA2G2A	-9296
FOLR2	-9285

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PLA2G5	-9553
HMGCS2	-9544
LYVE1	-9510
CYP4B1	-9506
PTGES	-9463
PTGIS	-9456
CYP2S1	-9450
ALDH1A1	-9446
CBR1	-9440
GSTM1	-9437
HPGDS	-9403
ADH1C	-9399
NMRAL1	-9398
CBS	-9387
MLXIPL	-9351
NQO2	-9337
CIDEA	-9300
PRELP	-9299
PLA2G2A	-9296
FOLR2	-9285
HSD11B1	-9280
LGMN	-9272
HSD3B7	-9229
SLC37A2	-9223
SULT1A1	-9221
HDC	-9208
NAGS	-9207
NT5E	-9206
LTC4S	-9192
DCN	-9178
TSTD1	-9167
MED16	-9159
RPS4X	-9157
PIK3R6	-9137
NUDT18	-9103
HS3ST2	-9099
SLC27A2	-9087
ORMDL2	-9086
CHST7	-9075
DSE	-9071
CBR3	-9070
ACBD6	-9054
ADH1B	-9051
SDC2	-9050
ACOX2	-9008
AAAS	-9006
SLC35B2	-8985
ARG2	-8970
AOX1	-8965
DDAH2	-8945
CYP21A2	-8924
HAAO	-8855
SGSH	-8851
LPIN3	-8812
CHPF	-8809
NUDT16	-8802
CKB	-8801
CRYM	-8795
GCKR	-8794
NUDT1	-8761
MAOB	-8759
ASS1	-8746
FUT4	-8745
HSD11B2	-8740
HPSE2	-8721
PTGS1	-8716
RPLP2	-8715
CA12	-8669
FPGS	-8656
CSAD	-8654
IP6K2	-8653
CYP26B1	-8642
UST	-8635
AIP	-8623
AKR1A1	-8614
GUSB	-8594
COMT	-8571
CRYL1	-8570
RPL3	-8564
BLVRB	-8557
VKORC1	-8551
NDST2	-8548
PAPSS1	-8545
MED15	-8524
TCN1	-8515
EBP	-8507
PLPP3	-8501
DEGS2	-8497
PHGDH	-8486
SEC13	-8457
GNA15	-8447
EXT1	-8440
MAN2B2	-8426
UCKL1	-8423
HMOX2	-8419
STX1A	-8416
RPL23	-8406
GSTT2B	-8384
IDUA	-8383
ADA	-8373
CDIPT	-8366
MOCOS	-8360
ARSA	-8348
NUBP1	-8330
BDH1	-8303
SARDH	-8296
RPS14	-8278
NT5C	-8277
D2HGDH	-8272
NDOR1	-8264
NADSYN1	-8263
RPS12	-8256
ADCY6	-8246
B3GAT3	-8238
PLCD1	-8237
RTEL1	-8235
LRP1	-8228
MED22	-8222
G0S2	-8218
HSPG2	-8195
PLCB3	-8190
EEFSEC	-8185
SMPD4	-8179
PFKFB3	-8175
RPL36	-8166
APRT	-8147
SIN3B	-8136
RPL19	-8133
ENPP2	-8131
RPS28	-8128
SREBF2	-8125
MPST	-8114
NSDHL	-8109
SLC27A3	-8096
PLAAT3	-8090
ADCY7	-8082
ST3GAL4	-8065
DHCR7	-8055
ACBD4	-8054
RPL28	-8031
CAD	-8030
CHPF2	-7993
UROD	-7983
PHYKPL	-7966
GSS	-7941
RPL37	-7930
ELOVL2	-7925
RPS26	-7908
MRI1	-7905
MED29	-7904
SLC3A2	-7899
ALDH2	-7881
ENO2	-7870
RPL31	-7842
CHST12	-7837
GCAT	-7830
AZIN2	-7809
APOM	-7786
PARP6	-7777
ATP5ME	-7774
HDAC3	-7742
NAXD	-7734
MAN2B1	-7733
CERS2	-7720
CUBN	-7712
RPL26L1	-7694
GAA	-7692
B3GALT6	-7687
SLC26A1	-7686
NUP188	-7684
MED11	-7665
PTPMT1	-7663
DCTD	-7658
HILPDA	-7649
UBA52	-7643
RPS5	-7633
PSMA7	-7617
POLD1	-7603
HAS3	-7598
BLVRA	-7592
PPARD	-7591
PSMB7	-7580
PSMC3	-7538
PGLS	-7523
GNB2	-7507
CHST3	-7500
UBE2I	-7499
ALDH18A1	-7487
SARS1	-7485
MVD	-7481
RPL13	-7472
RPS18	-7468
ACOXL	-7449
OSBPL5	-7441
ACOT13	-7416
PI4K2A	-7415
RPL7A	-7394
RPS16	-7390
CSNK2B	-7373
RPS10	-7354
NUP85	-7351
GALK1	-7346
RPL26	-7340
IP6K1	-7336
ACOT11	-7325
HSD17B10	-7304
PDPR	-7293
GPC3	-7281
ARF1	-7273
GNPDA1	-7272
MOCS1	-7258
RPL10A	-7253
PLD3	-7241
ACSM5	-7220
RPL30	-7217
ATP5F1E	-7215
ST6GALNAC6	-7211
BCO2	-7209
NAT8L	-7197
PDZD11	-7188
PLA2G15	-7168
SURF1	-7160
CPNE1	-7154
UCK1	-7146
RPS11	-7138
PSMD4	-7134
NDUFS5	-7133
RPL4	-7127
NAXE	-7121
CDO1	-7110
DHODH	-7104
GBA2	-7093
ENTPD6	-7087
FAU	-7067
GSTP1	-7057
ABCC2	-7046
CSPG5	-7032
RPL13A	-7019
IDH3B	-7016
HEXA	-7007
TMEM86B	-7002
RGL1	-6987
AKT1	-6976
ANGPTL4	-6972
GNAI2	-6950
PSMC5	-6942
PTGR1	-6924
ACOT7	-6911
RPS17	-6903
MED8	-6902
AK8	-6888
ENPP1	-6885
SCAP	-6872
PDXK	-6865
ASL	-6850
LSS	-6845
GNB1	-6844
STARD3	-6842
SUMF1	-6840
CHST14	-6822
GCHFR	-6812
SRM	-6809
DDO	-6786
CTSA	-6775
RPS15	-6758
ALOX12	-6746
GPS2	-6743
ARNT	-6740
RPL29	-6731
ACP5	-6730
QARS1	-6720
LRP10	-6714
SEC24C	-6711
TRMT112	-6708
PSMD8	-6703
COX6A1	-6702
PHKG2	-6697
ASPG	-6683
ELOVL1	-6681
ABHD14B	-6677
RPL36AL	-6668
CACNA2D2	-6650
PI4KA	-6641
PLIN1	-6628
CHAC1	-6624
GBA	-6620
PNPLA7	-6619
PIK3R2	-6618
STARD5	-6610
GMPR2	-6584
IDH3G	-6576
TNFAIP8L2	-6575
PLD2	-6574
SULT1A4	-6566
GNAS	-6561
PTPN13	-6540
RPS20	-6537
G6PD	-6534
RPL38	-6495
AGPAT4	-6489
PFKL	-6488
RPL12	-6483
PTDSS2	-6462
ETNK2	-6457
PPP2R1A	-6433
NDUFA11	-6423
PSMB4	-6417
RPLP0	-6397
PCK2	-6396
ARSI	-6394
MMS19	-6372
B4GAT1	-6368
B3GNT7	-6363
ACSS1	-6358
RPL10	-6333
PPOX	-6319
SLC25A28	-6312
PLEKHA6	-6307
MARS1	-6302
RPL8	-6300
ADCY3	-6292
FAM120B	-6275
MED12	-6227
POM121	-6225
CIAO2B	-6224
RPL5	-6221
EPHX2	-6215
NDUFAF3	-6214
NME4	-6211
MED25	-6204
HEXB	-6186
PLA2G6	-6181
PCBD1	-6178
FBP1	-6177
BSG	-6157
SHPK	-6150
RUFY1	-6141
RPL37A	-6135
CYB5A	-6124
RPL27A	-6113
SLCO2B1	-6101
TM7SF2	-6095
HYAL2	-6089
AOC3	-6082
ARF3	-6068
TAZ	-6061
GLB1L	-6042
COASY	-6040
SLC52A2	-6036
SAMHD1	-6035
PIAS4	-6009
GPAT4	-6004
MTHFD1L	-5998
ITPR3	-5979
NCOR2	-5973
RXRB	-5966
RPS2	-5959
RPS8	-5958
PYCR2	-5943
SRR	-5937
SULT1A2	-5935
AACS	-5919
CAV1	-5915
SBF1	-5905
RPS21	-5899
STXBP1	-5894
SDC1	-5891
PISD	-5884
IMPDH2	-5882
PSPH	-5878
PARP16	-5876
NME3	-5873
RPL11	-5867
RPS27	-5866
B4GALT7	-5857
ALDH3B1	-5850
PPARG	-5849
RPLP1	-5846
FABP4	-5844
FABP3	-5840
NME2	-5825
MED19	-5820
RPS6	-5819
GLUD1	-5816
PLIN3	-5812
ATIC	-5803
ITPA	-5796
PODXL2	-5784
MBTPS1	-5783
SIN3A	-5782
ESYT1	-5779
PSMD9	-5765
CYGB	-5763
RPL17	-5749
RHCE	-5748
DTYMK	-5742
G6PC3	-5729
SMPD2	-5728
PIP5K1C	-5724
DLST	-5722
PMVK	-5714
NDUFB8	-5703
RPL15	-5698
CD44	-5695
CHKB	-5671
AGPAT1	-5669
ADIPOQ	-5666
MED9	-5649
IDS	-5638
LIPE	-5637
NDUFA3	-5635
RRM1	-5626
CYP4V2	-5622
GLUL	-5619
CIDEC	-5609
RPL32	-5598
NCOA6	-5597
PPP2R5D	-5593
TNFAIP8	-5588
HS6ST1	-5575
HSP90AB1	-5567
PYGB	-5555
NR1D1	-5554
CA6	-5535
SLC27A1	-5525
GRHPR	-5515
ACOT8	-5511
VCAN	-5502
ENOPH1	-5499
CES2	-5498
LPIN2	-5496
PSMF1	-5494
MED24	-5491
CREBBP	-5487
NUBP2	-5486
POMC	-5478
SUMF2	-5457
MTMR14	-5434
PRODH	-5423
RPL41	-5397
AHCY	-5382
IMPDH1	-5362
RPL18	-5360
ETFB	-5359
ACOX3	-5355
B4GALNT2	-5353
PFAS	-5350
TRIB3	-5342
AGRN	-5337
PSMB3	-5327
MAOA	-5293
CNDP2	-5287
SHMT2	-5268
COX19	-5259
PLCD3	-5256
RPL23A	-5246
MOCS3	-5245
PSMD3	-5235
MED20	-5234
THRAP3	-5228
PECR	-5225
MTHFD1	-5218
B4GALT2	-5212
NHLRC1	-5192
GLTP	-5191
RHD	-5189
CYP27A1	-5186
PSMB1	-5182
GUK1	-5159
POR	-5156
RPL34	-5148
FMOD	-5144
NMRK2	-5142
HK1	-5138
ALDH7A1	-5131
PARP10	-5128
DUOX1	-5121
PI4KB	-5111
PSMD7	-5070
GCK	-5069
RPL7	-5057
TACO1	-5034
PRKD1	-5018
RPL18A	-5015
CERS5	-4994
PEX11A	-4985
UBIAD1	-4960
DCXR	-4957
FDPS	-4953
PSMD14	-4951
PSMB10	-4948
RPL6	-4942
RPS23	-4940
GCDH	-4935
PNPLA6	-4931
TKFC	-4920
ACACB	-4885
RAN	-4882
PSMC2	-4880
ADH5	-4874
PSMB6	-4849
RPS19	-4848
RXRA	-4843
RPS3	-4842
GM2A	-4837
TST	-4834
COX14	-4833
HMOX1	-4801
BCKDHA	-4789
INPP5E	-4778
GPIHBP1	-4776
KHK	-4767
NEU1	-4754
MAN2C1	-4746
PGD	-4744
PSMD2	-4715
MVK	-4712
CYSLTR2	-4710
PTDSS1	-4703
PYCR1	-4700
ALAS2	-4698
CIAO3	-4691
CYP39A1	-4668
NADK	-4665
B4GALT4	-4660
FAAH	-4656
ORMDL3	-4652
GPHN	-4648
HACL1	-4627
SLC5A6	-4616
SPHK2	-4612
DHRS7B	-4609
NDUFA2	-4601
NDUFB10	-4594
DGUOK	-4592
NUP62	-4588
PSMA1	-4587
VAC14	-4583
AKR7A3	-4580
FDXR	-4565
RPL14	-4555
HADH	-4547
BCKDK	-4541
PLAAT5	-4529
INPP5K	-4505
TPR	-4504
NAGLU	-4499
MLX	-4489
FLAD1	-4478
GALT	-4454
CIAPIN1	-4451
NR1H2	-4446
CSNK1G2	-4443
RNLS	-4441
B4GALT3	-4430
SEC24D	-4415
GPX4	-4406
DGAT1	-4399
GSTM4	-4375
PSMA5	-4364
CSNK2A2	-4363
CHST13	-4345
CYB5R3	-4343
PSMD10	-4338
LHPP	-4310
PFKFB1	-4297
TBXAS1	-4294
PSMD1	-4278
PLEKHA4	-4263
PLIN2	-4251
ETHE1	-4248
ACAA1	-4233
GNA11	-4230
TNFRSF21	-4228
HPGD	-4220
ARSG	-4219
MED10	-4199
ABHD5	-4189
CDS1	-4183
MGST3	-4180
NUP214	-4176
RPS15A	-4165
NDUFA13	-4153
PHKA2	-4152
SLC9A1	-4147
SREBF1	-4142
PSAP	-4139
ISYNA1	-4124
ABCD1	-4104
ALAD	-4101
ACSS2	-4089
LYRM4	-4080
LUM	-4064
ACAA2	-4060
EXT2	-4054
HMGCL	-4052
XYLT2	-4023
PDK2	-4013
PC	-4006
ISCU	-4004
MED26	-3975
FDX2	-3970
BTD	-3962
INPPL1	-3958
NUBPL	-3949
ACSF3	-3946
SLC16A8	-3945
RPL27	-3935
CEMIP	-3931
LPL	-3905
DCTPP1	-3889
PARP4	-3881
ECSIT	-3850
PGS1	-3837
PFKFB2	-3824
MED30	-3819
PFKP	-3818
RAE1	-3807
SLC19A3	-3793
RPL35	-3792
MED27	-3774
ESYT2	-3773
CYP2A6	-3762
CSPG4	-3747
B3GALT4	-3720
TK2	-3718
ATP5MF	-3715
RPL39L	-3699
NUP88	-3689
NOSIP	-3680
POM121C	-3677
VAMP2	-3662
PNPLA3	-3653
AGPAT2	-3604
ACAT2	-3588
FAH	-3570
RPL39	-3539
KYAT1	-3535
OAZ1	-3532
PSMC4	-3510
CACNB3	-3506
OPLAH	-3491
DHCR24	-3482
CD320	-3476
CA1	-3457
GPD1	-3454
TXN2	-3453
IVD	-3441
PGAM1	-3438
CHKA	-3431
SMPD1	-3429
CERS4	-3425
AMN	-3420
CTH	-3415
NNMT	-3409
NUP98	-3400
PTGES2	-3395
FDFT1	-3388
MCAT	-3385
HYAL1	-3376
MLYCD	-3373
HMBS	-3366
RAPGEF3	-3364
FUT11	-3351
MED1	-3350
ABHD4	-3349
DBI	-3325
ARSB	-3324
PRKD2	-3320
PLCG1	-3308
HADHA	-3287
BCAT2	-3285
ACLY	-3281
NDUFS4	-3278
KARS1	-3275
SMOX	-3260
GYG2	-3259
PLA2R1	-3256
RPS9	-3253
PPP2CB	-3249
UQCR10	-3240
SDC3	-3226
GNG7	-3213
DUOX2	-3204
NMNAT3	-3193
PSMB2	-3187
UCK2	-3177
NCOR1	-3170
NUP93	-3163
PNPLA2	-3157
RPS24	-3138
LDHB	-3132
ATP5MC2	-3127
GPAT2	-3101
ATP5MG	-3092
RIDA	-3089
RPS29	-3082
ST3GAL3	-3046
PLA2G2D	-3040
DMGDH	-3018
ITPK1	-3014
SQLE	-3013
PGP	-2988
OAT	-2969
NDUFB7	-2964
ALDH3A2	-2960
ADI1	-2952
NUP43	-2946
HAGH	-2942
ACSS3	-2931
DNM2	-2918
NAPRT	-2911
PCYT2	-2909
ADCY5	-2906
CA14	-2905
PXMP2	-2884
INPP5B	-2845
NUDT5	-2843
SERINC3	-2836
SC5D	-2819
SMS	-2818
GLYCTK	-2816
FAHD1	-2814
UBB	-2810
MORC2	-2806
NDUFS6	-2804
BGN	-2800
GGT1	-2784
ATP5PB	-2781
SLC25A19	-2776
COX4I1	-2771
HSP90AA1	-2745
CPTP	-2741
DECR2	-2730
ALDH1B1	-2712
KYAT3	-2690
OCRL	-2671
SLC2A1	-2646
MANBA	-2627
IPPK	-2622
THTPA	-2610
UBC	-2608
ENO1	-2605
ETFA	-2603
PANK4	-2590
NPAS2	-2583
XYLT1	-2579
PIK3R1	-2575
PPT2	-2573
TALDO1	-2571
PSMD6	-2563
GNG2	-2555
DNPH1	-2551
RETSAT	-2549
KPNB1	-2542
NRF1	-2535
ABCD4	-2525
APOB	-2510
DMAC2L	-2501
SCLY	-2498
PSMB5	-2492
ERCC2	-2482
DHFR	-2466
PCCA	-2457
PSMD13	-2447
CHP1	-2435
SLC16A1	-2417
SLC25A10	-2409
ADIPOR1	-2407
SPR	-2391
CDA	-2389
HOGA1	-2384
ALDH6A1	-2363
FADS1	-2362
GGT5	-2348
PIP4K2B	-2338
UMPS	-2295
STARD10	-2289
FH	-2269
BHMT2	-2263
FASN	-2262
SERINC2	-2261
CDS2	-2257
PYGL	-2240
MTMR1	-2226
GSTA4	-2199
IDH3A	-2193
TSPOAP1	-2156
SLC44A2	-2155
HLCS	-2150
CPT1B	-2149
INPP5A	-2145
GSTZ1	-2143
ACAD10	-2134
CKMT2	-2116
PANK2	-2110
NDST1	-2107
ATP5PD	-2104
RDH11	-2102
NDUFB1	-2099
MFSD2A	-2096
NDUFA6	-2090
MTHFR	-2089
CARM1	-2078
NDUFV3	-2077
GSTM2	-2068
ADPRM	-2059
RPS27A	-2058
GNAI1	-2057
TIMMDC1	-2053
COX6B1	-2050
ACAD9	-2031
SUOX	-2029
ESRRA	-2017
XYLB	-2012
HSD17B8	-2010
SGPL1	-1996
PRKACA	-1995
FHL2	-1985
GALE	-1982
HK2	-1958
ECI2	-1951
PDSS1	-1939
RBP1	-1933
NDUFS8	-1921
NOS3	-1909
MGLL	-1904
FMO3	-1903
STK11	-1894
PIP4K2A	-1873
PAPSS2	-1870
PNMT	-1867
TRAP1	-1856
COX7C	-1852
EPHX1	-1844
ACAD8	-1843
ECI1	-1842
EPM2A	-1830
RPL35A	-1829
TIAM2	-1819
NCOA1	-1812
ABCB4	-1811
PLAAT4	-1804
SPTSSA	-1796
AKR1B1	-1787
SEPHS2	-1784
COX11	-1766
APIP	-1744
GSTM3	-1741
ACAD11	-1731
COX8A	-1726
NDUFB11	-1711
TBL1X	-1706
PPARA	-1702
ALDH1L2	-1700
PIK3R5	-1699
PSME3	-1691
BCAT1	-1687
SDSL	-1670
AHCYL1	-1655
PLBD1	-1643
DUT	-1640
N6AMT1	-1634
ME3	-1628
GLUD2	-1621
CPT1A	-1617
NDUFA7	-1605
UGDH	-1591
INPP5J	-1584
TPST2	-1578
CYP11A1	-1566
DDAH1	-1562
PRPS2	-1552
TPO	-1549
MAPKAPK2	-1543
TMLHE	-1540
GDE1	-1530
ADCY9	-1529
ADHFE1	-1528
PON3	-1525
MTMR4	-1520
THRSP	-1500
NDUFS3	-1471
PPP1CA	-1446
SLC46A1	-1435
PLA2G4B	-1431
NDUFA8	-1417
PRKAR2B	-1412
ACAN	-1392
GPI	-1390
AS3MT	-1380
COX6C	-1378
SLC22A3	-1366
PCCB	-1364
UQCR11	-1362
AFMID	-1356
AKR7A2	-1348
GLYAT	-1337
UQCRQ	-1332
EP300	-1330
MCCC2	-1327
ACP6	-1324
FECH	-1322
DIO3	-1321
ABCC1	-1307
GSTO1	-1291
SCO1	-1284
SLC19A1	-1281
ACADS	-1278
PSMC1	-1275
COQ5	-1273
ADRA2C	-1270
SULT1A3	-1264
TKT	-1261
ATP5PO	-1258
SLC25A1	-1255
PAOX	-1251
LPCAT4	-1248
HS3ST5	-1240
MED18	-1227
GPC6	-1226
ACY1	-1225
CRLS1	-1209
ACOT6	-1201
UCP2	-1199
RPS4Y1	-1198
PCTP	-1164
SDHB	-1153
ATP5F1D	-1152
TCN2	-1138
SLC23A2	-1118
ATP5F1A	-1114
AOC2	-1103
BPHL	-1041
NDUFV1	-1038
ACOT4	-1037
MTMR3	-1036
GPC1	-1028
GATM	-1026
UROS	-1014
OSBPL9	-1008
SDHA	-989
RIMKLA	-987
NMNAT1	-978
APOE	-966
AKR1B10	-964
NUDT15	-963
ACOT9	-946
ST3GAL2	-942
MED17	-928
UQCRC1	-926
GPT2	-919
NMRK1	-908
OMD	-898
SLC27A5	-875
HACD3	-844
FITM2	-828
ALDH9A1	-822
SHMT1	-818
NDUFB4	-809
SLC22A5	-789
SERINC5	-770
PPP2CA	-765
TPST1	-761
NDUFAB1	-749
NDUFA1	-741
SEM1	-739
TMEM186	-734
SLC25A11	-728
PCK1	-685
HAS1	-680
IARS1	-664
SEC24B	-641
PSME1	-634
ADIPOR2	-618
CRAT	-611
AGPAT3	-576
CA5B	-571
TYRP1	-554
PSMA2	-550
RPS25	-545
PLD6	-539
HS3ST1	-525
FMO1	-511
ABCB7	-503
EPRS1	-493
SLC35D2	-483
SPNS2	-478
GART	-471
TYMS	-465
CIAO1	-458
CPOX	-423
MINPP1	-422
SUMO2	-415
RPL21	-383
GDPD3	-376
CYC1	-374
MIGA2	-370
ADRA2A	-365
SRD5A3	-364
CYP3A5	-359
PCYT1A	-358
PSMD11	-353
PSMB8	-350
RPS3A	-334
ALOX5AP	-332
NFYC	-309
PM20D1	-296
RPS13	-295
ESD	-290
AGPS	-286
SYNJ2	-268
NT5M	-259
MTARC1	-252
HSD17B14	-250
NDUFS7	-228
MMAB	-209
NME1	-191
SPTLC1	-190
PLEKHA5	-189
TK1	-175
COX7B	-174
PITPNM1	-167
PUDP	-163
RPSA	-148
RARS1	-147
FDX1	-138
MID1IP1	-121
TSPO	-92
OGDH	-89
MPC1	-81
ACADL	-79
GYG1	-78
ACADVL	-74
MDH2	-70
NUP155	-51
RAB4A	-45
SP1	-44
LIPT2	-33
SLC25A20	-2
GMPS	-1
VKORC1L1	1
SLC6A8	9
CPS1	26
NUDT9	29
ACOT2	31
ETFDH	35
OSBPL3	42
ARNT2	49
CHAC2	51
CYB5B	63
IDH1	67
ACAT1	74
NDUFB9	82
HNMT	85
GLB1	88
PITPNB	101
ELOVL5	111
COX10	126
RBP4	127
GDPD5	130
MMUT	157
PPCS	165
PIP5K1A	179
SLC25A17	192
MED7	200
AUH	207
TPI1	217
GNMT	225
ENPP3	226
TXN	237
ARSD	272
THEM5	278
NFS1	286
NUP42	299
PLPP6	310
ACSL1	312
NDUFA12	318
GAPDH	327
ADCY2	328
BHMT	338
PSAT1	341
MTHFS	355
COQ2	356
HSD17B4	367
OSBP	368
PIK3R4	371
NAT1	375
DSEL	378
HK3	383
PLB1	387
NUDT19	392
COX5B	415
QDPR	421
LPCAT1	425
ABCC3	431
PRPS1	441
ADPGK	444
MED28	449
ATP5MC3	466
PLCH2	471
UQCRFS1	489
CTPS1	496
MCCC1	511
PITPNM2	512
SECISBP2	526
PDHA1	536
SLC51B	539
ACOX1	542
OSBPL2	553
COQ9	572
MTF1	574
TECR	582
PHYH	602
ACACA	604
PSME4	609
SMPD3	621
IQGAP1	633
GSTK1	648
AADAC	649
HPD	655
CYP2D6	659
GBE1	666
NDUFC2	668
IDI2	674
PLD1	679
ALDH4A1	704
OGN	706
DEGS1	722
ATP5MC1	729
NEU3	745
PPT1	750
ADO	770
STS	774
TNFAIP8L3	778
NUDT7	786
SLC37A1	792
DIO2	796
PLA2G12A	800
NUP205	808
HADHB	821
GPC4	836
CERK	849
SUCLG1	881
SGMS1	885
STAB2	887
COQ6	889
SLC25A15	917
RPIA	918
GPAM	919
AMPD2	931
HSD17B1	941
GPT	991
COX18	993
TYMP	1004
SLC25A16	1020
UPP1	1030
NDUFC1	1042
NDUFB2	1073
ISCA2	1084
MTMR12	1096
MTARC2	1135
OXCT1	1141
AIMP1	1167
COQ10A	1169
SLC52A3	1173
HACD1	1190
RPS7	1197
HACD2	1214
KDSR	1224
PRXL2B	1229
RPS27L	1251
RPL22	1273
CYP2U1	1285
RPL24	1297
PLEKHA8	1299
PIPOX	1301
NDUFA10	1304
GSR	1306
SLC44A3	1308
NDUFAF1	1311
VAPB	1316
PSTK	1324
ENTPD7	1325
BST1	1355
ACO2	1357
NUP210	1376
AK2	1379
GPD1L	1403
GCLC	1414
DDHD2	1424
ECHS1	1433
BDH2	1446
GLIPR1	1460
SLC51A	1465
PDHB	1492
AKR1C1	1494
BPNT2	1508
SDHC	1518
SBF2	1522
COX15	1546
FIG4	1569
NUP153	1582
ALOX5	1588
HIBCH	1595
PLCB2	1596
PSMA6	1616
SLC37A4	1623
NDUFS2	1637
ATP5F1B	1639
AMPD3	1643
NUP160	1654
PEMT	1662
PAICS	1667
CSNK2A1	1672
ABHD10	1678
B4GALT5	1683
GNB3	1692
HPRT1	1703
PSMA3	1706
SPHK1	1734
HIBADH	1739
ENPP6	1743
PGAM2	1744
UQCRH	1746
MBOAT1	1750
GNPAT	1758
SDC4	1761
LPCAT3	1774
NUDT13	1780
MCEE	1787
OAZ3	1819
AADAT	1837
PLA2G4C	1854
PSMC6	1856
DGAT2	1860
HSD17B12	1880
KCNJ11	1893
UQCRC2	1895
GLCE	1912
COX5A	1913
PDP2	1914
AK6	1919
HSCB	1928
SDHD	1933
INPP4A	1968
NDUFAF4	1978
UQCRB	1987
OAZ2	1990
MED21	1991
DBT	2023
ALDH3A1	2041
HSD17B7	2066
PLPP2	2080
TNFAIP8L1	2082
TMEM126B	2083
FAR2	2086
SLC25A44	2095
GYS1	2096
NDUFB3	2098
GLRX5	2125
MMADHC	2158
DPEP2	2161
PITPNM3	2167
ISCA1	2174
THEM4	2182
ELOVL3	2186
PPIP5K1	2190
ARSJ	2234
CS	2242
SORD	2253
MMACHC	2254
GCSH	2277
CHPT1	2279
PPCDC	2283
CYP2R1	2298
CD38	2304
KCNB1	2321
AGPAT5	2325
ARV1	2326
FITM1	2328
NUP54	2334
TGS1	2340
GLA	2349
CERS6	2352
AKR1C2	2364
MED4	2365
GNG5	2366
TXNRD1	2385
MT-ATP8	2391
MTRR	2393
MPC2	2395
CDK8	2400
GNB5	2405
ST3GAL1	2406
CYP2J2	2412
VDAC1	2423
FADS2	2428
SUCLG2	2430
MGST1	2451
DHTKD1	2452
ADCY1	2469
SCD	2474
INPP1	2500
ST3GAL6	2512
ATP5F1C	2517
PDK1	2524
CKM	2528
PLCE1	2534
MED31	2538
GYS2	2540
GGCT	2551
BPGM	2579
ASPA	2581
CPT2	2593
DHFR2	2625
NUP35	2637
GPC2	2638
AIMP2	2640
DLD	2657
DERA	2665
NADK2	2701
GOT1	2716
COX20	2734
HELZ2	2739
GNPDA2	2740
AGK	2744
ACSL3	2747
STARD7	2768
DARS1	2769
BPNT1	2774
GPX1	2781
ADCY4	2789
LDLR	2820
RRM2	2826
PPA1	2829
ADAL	2834
ME1	2841
GNG12	2843
ADK	2847
DPYD	2855
PRKAG2	2857
IDH2	2868
VAPA	2874
B4GALT1	2878
PNPLA4	2890
UGP2	2907
AMT	2929
INMT	2937
L2HGDH	2939
HYAL3	2942
PHKG1	2962
ALDH1L1	2972
GGT7	2978
SACM1L	2988
ARNTL	2989
NT5C2	3026
ACBD5	3027
NR1H3	3041
PRKG2	3047
CA3	3053
FUT10	3068
MED6	3079
SLC25A14	3086
NDUFV2	3094
ACER2	3130
SPTLC2	3148
COA1	3149
CYP4F12	3153
PSMD5	3165
PIK3C3	3169
OSBPL1A	3178
B4GALNT1	3183
ALDOA	3204
PIP5K1B	3219
ORMDL1	3238
MTR	3250
SEC23A	3257
CPNE3	3289
PSME2	3291
SERINC1	3302
NDUFS1	3322
CERS1	3331
MED13L	3347
AGT	3348
FBP2	3349
ASNS	3352
DECR1	3355
ENTPD5	3398
COQ3	3407
EHHADH	3414
CMPK1	3419
PRKD3	3437
ABCC8	3438
SEC24A	3440
NDUFA4	3446
PIP4K2C	3448
ELOVL6	3454
MAT2B	3460
SGPP1	3461
OSBPL10	3473
ACSF2	3495
TTPA	3500
GRHL1	3514
ENTPD4	3526
GLO1	3528
ADSL	3536
SCO2	3548
ELOVL4	3555
PRKAR1B	3558
ODC1	3565
PON2	3593
ENO3	3595
PRKACB	3604
AZIN1	3605
PYGM	3610
PDHX	3627
ASAH1	3647
INPP5D	3651
SUCLA2	3664
HPSE	3679
NDUFA9	3685
SLC35B3	3688
NNT	3690
SLC25A37	3691
MOCS2	3706
GGPS1	3711
SMARCD3	3724
NFYB	3729
CACNA1C	3739
ACOT1	3757
RPL3L	3763
CES3	3769
B3GALT1	3770
ARSK	3775
SLC7A5	3790
NDUFAF7	3799
FLVCR1	3805
FMO2	3808
SLC25A27	3820
CYP2E1	3828
MT-ATP6	3857
SCP2	3858
PHKA1	3861
CBSL	3863
ITPR1	3869
PNPLA8	3871
AMPD1	3875
CEPT1	3879
ALAS1	3893
ITPKC	3903
SAMD8	3904
CYP51A1	3943
FXN	3980
PPM1L	3997
PLA2G4F	3998
CHD9	4007
INPP5F	4019
ENTPD2	4022
LPIN1	4027
RPE	4040
GNGT2	4058
PSMA4	4076
KCNS3	4106
NUDT11	4132
GPCPD1	4162
PPARGC1A	4165
PKM	4173
AKAP5	4212
GPAT3	4231
SLC26A2	4252
SGMS2	4258
PSMB9	4260
MT-CO1	4282
MT-CO2	4296
MTAP	4304
ENTPD1	4333
AK5	4334
PLPP1	4345
IMPA2	4350
PNPO	4359
HS2ST1	4386
LMBRD1	4401
LRPPRC	4414
BCKDHB	4446
PLAAT1	4481
GMPR	4485
ANKRD1	4521
COX7A2L	4527
PLA2G4A	4547
PSMD12	4558
RAB14	4562
CHST15	4575
DCT	4582
SLC35D1	4597
TPMT	4609
CA4	4611
CERT1	4627
PRKAR2A	4641
PTGR2	4645
RAP1A	4646
NT5C1A	4676
LRP8	4683
NDC1	4688
CSGALNACT1	4694
GAMT	4697
MTMR2	4699
SLC19A2	4707
NUDT3	4716
NUP133	4739
MBTPS2	4743
PPP2R1B	4784
GSTM5	4789
PRKCA	4793
TPK1	4797
PGK1	4836
DCK	4838
CYP19A1	4839
PPP1CC	4852
NMNAT2	4879
PRKAB2	4901
NUP107	4939
INSIG1	4970
CA2	4994
CHST1	4995
CMBL	5002
LPGAT1	5005
MT-ND5	5007
PFKFB4	5016
CROT	5031
AMDHD1	5033
MT-CYB	5065
QPRT	5067
PGM1	5076
COQ7	5092
CTPS2	5093
RANBP2	5097
GOT2	5112
GLRX	5116
LTA4H	5120
PLEKHA2	5126
NDUFAF6	5129
PIK3CA	5148
PLCG2	5152
PTS	5163
SLC16A3	5171
CD36	5193
ATP5PF	5203
SAR1B	5213
SCD5	5231
SEPSECS	5248
CYP1B1	5259
CALM1	5275
HMGCLL1	5299
DLAT	5309
TBL1XR1	5336
ALDOC	5341
ASRGL1	5347
ACSBG1	5353
PIK3C2B	5376
PGM2	5378
NDUFAF2	5397
ITPKB	5410
PGM2L1	5411
CHDH	5433
SGPP2	5438
ACER3	5452
PPA2	5481
GCLM	5491
AKR1B15	5499
PLD4	5520
MTMR10	5530
AK9	5537
PHOSPHO1	5538
ACHE	5540
HMGCS1	5550
AHRR	5553
IL4I1	5573
PLEKHA3	5596
ABCA1	5607
GNS	5625
LDHA	5642
MBOAT7	5651
AASS	5668
GNG10	5674
MECR	5698
PPP1R3C	5705
CA13	5722
ABO	5734
NUP37	5735
PTGES3	5736
BMX	5748
PPARGC1B	5758
PTEN	5760
MT-ND6	5763
BAAT	5768
EEF1E1	5800
SLC25A12	5806
ABCB11	5813
ACSL5	5820
PDSS2	5824
PANK3	5826
NUP50	5855
PRKAR1A	5856
NFYA	5867
MTMR9	5869
SELENOI	5874
VDR	5889
MOGAT2	5906
STARD3NL	5908
GALC	5917
PPIP5K2	5921
ACSL6	5930
ABCC5	5949
PLA1A	5956
PHKB	5969
B3GAT2	5970
PFKM	5979
MTMR7	5985
RIMKLB	5998
HS3ST3B1	6002
PTGDS	6043
SLC25A13	6058
AASDHPPT	6062
PI4K2B	6064
SLC25A32	6066
HSD17B11	6068
MTM1	6076
SEH1L	6077
ITPR2	6099
WASL	6108
MED14	6117
UPB1	6120
LRP12	6131
MOGAT1	6134
MDH1	6144
PDP1	6166
PPM1K	6182
ARG1	6199
UCP3	6206
MSMO1	6235
NAALAD2	6242
MTHFD2	6260
PARP8	6264
LARS1	6265
AK1	6326
SLC44A1	6330
AK4	6360
HACD4	6369
RPL9	6370
PPAT	6380
INSIG2	6382
IDI1	6390
PIKFYVE	6405
ACADM	6413
SLC6A12	6441
MED23	6444
IP6K3	6447
B3GNT2	6463
NQO1	6478
CBR4	6479
DDHD1	6488
NDUFAF5	6494
AKR7L	6495
RFK	6526
TECRL	6537
GNA14	6546
LIAS	6549
ABCB1	6558
ME2	6573
ACADSB	6577
UGT3A1	6583
RPL22L1	6595
AKR1C3	6598
RAB5A	6603
CHST2	6650
HS6ST2	6656
SAT1	6660
SLC44A5	6686
HYKK	6691
CARNMT1	6724
PDK3	6733
SLC25A21	6741
PIK3CG	6745
GDA	6760
SDS	6788
MTHFD2L	6789
GSTT2	6795
PLEKHA1	6805
RPL36A	6879
PIK3R3	6894
MT-ND4	6917
FABP5	6919
NDUFB5	6920
GLDC	6928
PPP1CB	6943
ASAH2	6958
CLOCK	6976
SYNJ1	6983
KYNU	7028
PARP14	7049
LPCAT2	7062
PIK3CD	7072
ABHD3	7075
PIK3CB	7088
ACSL4	7089
OSBPL7	7093
CES1	7111
CHST11	7113
TPH1	7138
ENTPD3	7139
FABP7	7159
ZDHHC21	7173
CYCS	7197
CYP7B1	7199
LIPT1	7224
MMAA	7252
ABCG2	7311
AMD1	7345
CSGALNACT2	7364
NUDT4	7375
SLC36A4	7449
MIGA1	7477
MT-ND2	7484
GDPD1	7506
HSD17B13	7507
NOSTRIN	7534
B3GAT1	7545
HMGCR	7550
VNN1	7572
MT-ND1	7626
ETNK1	7646
GADL1	7652
NT5C3A	7658
CDK19	7660
PLCD4	7665
AMACR	7675
PARP9	7678
AGMAT	7684
RBKS	7686
GLS	7721
RRM2B	7726
CCNC	7737
HAL	7743
PNP	7744
CHSY3	7746
NDUFB6	7762
PLCB1	7774
INPP4B	7794
HAS2	7805
PIK3C2A	7865
ACSM2B	7899
CARNS1	7907
MARCKS	7916
B3GALNT1	7950
PLCB4	7956
IMPA1	7961
FAR1	7974
KMO	8008
MT-CO3	8009
MGST2	8031
MBOAT2	8042
FUT1	8059
COX16	8068
CACNA1A	8074
FUT7	8084
GNG11	8107
RAPGEF4	8117
B4GALT6	8123
PRKAA2	8155
CHSY1	8158
MED13	8171
MAT2A	8173
ELOVL7	8179
HSD17B2	8187
LRP2	8191
OSBPL8	8198
SULT1C4	8199
BRIP1	8237
CACNA1D	8254
ACSM2A	8286
IPMK	8297
COQ10B	8301
HTD2	8320
AK7	8324
GK	8328
CACNB2	8387
AGMO	8388
NDUFA5	8439
GNAQ	8465
OSBPL6	8478
NUDT12	8492
PANK1	8499
GNB4	8519
NCOA2	8533
FOLH1	8540
ACSM3	8542
AGXT	8556
BCHE	8567
FUT2	8590
MT-ND3	8619
PDK4	8624
SPTLC3	8651
GPD2	8673
LCLAT1	8677
NCOA3	8710
ACBD7	8737
IDO1	8745
AHR	8750
NUP58	8794
SRD5A1	8805
CHRM3	8828
STARD4	8856
SULT1B1	8858
LBR	8871
MTMR6	8879
GSTO2	8919
RORA	8950
LYPLA1	8980
SYT5	9048
TPH2	9095
CHST5	9128
CYP4F3	9150
GCH1	9174
CH25H	9237
CYP2C9	9355
AGL	9361
UGCG	9363
NAMPT	9404
CYP46A1	9419
SLC2A3	9446
SULT1C2	9449
VNN2	9461
PTGS2	9471

---

Vesicle-mediated transport

Vesicle-mediated transport

	1403
set	Vesicle-mediated transport
setSize	645
pANOVA	1.3e-10
s.dist	-0.149
p.adjustANOVA	3.94e-09

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MARCO	-9567
DNM1	-9560
SCARA5	-9547
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
RAB3IL1	-9391
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
TBC1D3	-9311
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
CCZ1	-9286

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MARCO	-9567
DNM1	-9560
SCARA5	-9547
IGLV3-1	-9534
IGLV5-45	-9525
IGLV2-14	-9482
IGLV8-61	-9471
IGLV7-46	-9444
IGKV1-5	-9421
IGLC3	-9405
RAB3IL1	-9391
IGHV3-7	-9357
IGKV3-11	-9342
IGLV2-8	-9316
TBC1D3	-9311
IGHV2-5	-9310
IGLC1	-9301
IGLV3-25	-9291
IGHV3-33	-9287
CCZ1	-9286
SSC5D	-9274
KDELR3	-9269
IGLV2-11	-9267
IGKV1-17	-9251
IGKV2-28	-9249
IGLC2	-9098
IGHV3-11	-9041
BET1L	-9024
AP1M1	-8972
AP2A2	-8966
COLEC12	-8917
IGHV3-30	-8906
SRC	-8900
CTTN	-8876
MASP1	-8868
SNX9	-8785
SNF8	-8773
PACSIN1	-8752
CTSZ	-8730
KDELR1	-8717
IGLV1-47	-8713
IGLV3-21	-8651
CHMP2A	-8605
CD4	-8579
GGA3	-8567
ARFGAP1	-8534
KIF16B	-8533
STAB1	-8531
IGKV3-15	-8522
DVL2	-8480
COPG2	-8478
ARFIP2	-8467
SEC13	-8457
RIN2	-8442
IGKV3-20	-8400
COL1A1	-8334
STX4	-8290
SH3GL1	-8287
HGS	-8283
LRP1	-8228
COL1A2	-8169
BLOC1S4	-8159
TMEM115	-8152
RAB41	-8148
IGLV2-23	-8106
DCTN1	-8089
IGHA2	-8079
CD163	-8028
PAFAH1B3	-7990
IGLV3-19	-7984
TFG	-7967
RAB11B	-7954
TBC1D25	-7939
ARFRP1	-7902
COPZ2	-7828
TMED9	-7815
GOLGA2	-7731
HPS1	-7725
DTNBP1	-7722
VPS51	-7683
SNX2	-7681
UBA52	-7643
TXNDC5	-7608
HYOU1	-7602
GORASP1	-7588
CHMP4A	-7578
RAB35	-7555
ITSN1	-7501
GPS1	-7470
IGHV4-59	-7466
VPS25	-7451
BLOC1S1	-7447
KIFC2	-7414
TBC1D2	-7388
VPS28	-7361
COPE	-7337
AP2A1	-7331
SYS1	-7329
ARF1	-7273
KLC1	-7249
SPTBN1	-7208
AP2M1	-7207
TBC1D20	-7150
ARPC1A	-7142
PACSIN2	-7130
GDI1	-7116
LMAN2	-7109
RAB7B	-7091
USE1	-7075
AP1B1	-7052
EXOC7	-7047
BLOC1S3	-7045
SEC31A	-7037
SCARB1	-7020
IGKV2-30	-7018
KDELR2	-7005
CD55	-6985
AKT1	-6976
TBC1D17	-6975
COPG1	-6927
COPA	-6918
COL3A1	-6917
DENND2A	-6912
DENND4B	-6863
AKT2	-6860
CALR	-6854
STX5	-6846
TRAPPC2L	-6791
IGKV4-1	-6785
SEC24C	-6711
TRAPPC12	-6710
CYTH4	-6665
CYTH3	-6640
IGLV6-57	-6578
RAB32	-6555
RABEPK	-6535
GGA2	-6509
COPS7B	-6459
TRIP10	-6429
CSNK1D	-6427
MYO1C	-6410
TSC2	-6377
YWHAH	-6296
CAPZB	-6272
GGA1	-6262
DENND6B	-6199
FTH1	-6184
PLA2G6	-6181
MAN1C1	-6164
TMED3	-6134
NECAP2	-6133
EGFR	-6115
CHMP4B	-6078
TOR1A	-6070
ARF3	-6068
FNBP1	-6066
TBC1D13	-6050
ANK2	-6049
AP4M1	-6023
IGLV1-40	-5992
COPS6	-5971
GOLGB1	-5951
TBC1D10A	-5914
SBF1	-5905
DENND1A	-5903
ARF5	-5847
PLIN3	-5812
GAK	-5764
IGHV4-39	-5760
YKT6	-5757
RAB13	-5745
RABGAP1	-5736
PIP5K1C	-5724
TRAPPC3	-5699
IGKV2D-28	-5697
NEDD8	-5659
VPS4A	-5655
ARFGAP2	-5642
RIN1	-5639
TBC1D14	-5604
TBC1D16	-5601
AP2B1	-5595
DAB2	-5592
RINL	-5568
GRK3	-5556
POLG	-5546
AP2S1	-5530
IGHV1-2	-5528
DCTN2	-5482
STX10	-5451
RAB1B	-5419
ASPSCR1	-5391
SURF4	-5379
CTSC	-5303
ANKRD27	-5298
SPTAN1	-5267
IGLV1-51	-5257
CHMP3	-5253
AP1S1	-5221
IGKC	-5210
TRAPPC1	-5198
ARPC2	-5195
TRAPPC5	-5179
RGP1	-5158
KIF3B	-5153
KLC4	-5074
SEC22C	-5067
SNAP29	-5055
DENND2D	-5037
CLTA	-5023
PRKAB1	-5000
CHMP6	-4996
APP	-4981
PRKAG1	-4971
ARRB1	-4930
DCTN5	-4917
MYO5A	-4904
PPP6R1	-4901
COPS7A	-4832
TRAPPC6A	-4822
COG1	-4818
ACTR1A	-4804
COPB2	-4799
BNIP1	-4797
IGHA1	-4732
LDLRAP1	-4643
IGKV1D-39	-4621
AGTR1	-4604
GJA5	-4576
MVB12B	-4567
IGKV1-12	-4498
AP1G2	-4497
GOSR2	-4481
KIF22	-4471
DYNC1H1	-4438
RAB31	-4420
ARCN1	-4417
SEC24D	-4415
CLTB	-4405
M6PR	-4391
STON2	-4379
TF	-4330
BICD2	-4313
SEC16A	-4307
EXOC3	-4304
MAN2A2	-4296
AP3B1	-4267
NBAS	-4245
TSC1	-4240
STX18	-4227
KIF18B	-4226
RAB27B	-4194
DYNC1I2	-4164
RAB5C	-4159
DCTN3	-4136
GALNT2	-4034
RAB5B	-4030
DYNLL1	-4027
COPZ1	-4005
HSPA8	-3981
EPN1	-3966
GJC2	-3928
GABARAP	-3921
ARPC4	-3888
SORT1	-3841
COPB1	-3776
COG8	-3739
GRK2	-3694
MON1B	-3682
GBF1	-3681
VAMP2	-3662
VPS37C	-3658
RABGEF1	-3655
IGHV4-34	-3644
TRAPPC10	-3582
AVPR2	-3554
ARFGAP3	-3514
AMPH	-3393
SNAPIN	-3370
MVB12A	-3360
RALA	-3340
COG7	-3309
COG4	-3282
KIFC1	-3271
TOR1B	-3261
ULK1	-3224
SH3KBP1	-3219
CLTC	-3186
CHMP7	-3149
VPS45	-3124
BTC	-3119
GOLGA1	-3097
VPS37D	-3017
RACGAP1	-2976
VAMP8	-2972
COL4A2	-2955
RIN3	-2953
NAA38	-2925
DNM2	-2918
MON1A	-2914
LMAN2L	-2910
KIF13B	-2861
UBB	-2810
RAC1	-2805
TGOLN2	-2798
KIF11	-2777
NAPA	-2751
HSP90AA1	-2745
KIF1C	-2726
OCRL	-2671
RAB9A	-2612
UBC	-2608
CYTH2	-2524
VAMP3	-2517
APOB	-2510
ARRB2	-2487
SEC22A	-2458
EPS15L1	-2443
VPS52	-2396
SPARC	-2377
FTL	-2370
KIFAP3	-2355
SPTA1	-2312
SNX5	-2300
HSP90B1	-2260
GDI2	-2249
PUM1	-2209
HIP1	-2169
DNASE2	-2146
GOLGA5	-2122
DCTN6	-2064
RPS27A	-2058
OPTN	-1916
RAB38	-1805
CUX1	-1771
TMED10	-1755
STX6	-1697
RAB8A	-1652
TSG101	-1644
YWHAE	-1609
SH3D19	-1603
TBC1D10B	-1564
RAB3GAP1	-1493
MSR1	-1454
COPS4	-1359
KIF9	-1351
HPS4	-1314
IGLV1-44	-1280
RAB1A	-1175
COPS3	-1083
AP4B1	-1068
KLC2	-1024
RAB3A	-1022
RAB7A	-1021
EPN2	-1004
APOE	-966
YWHAG	-935
PREB	-921
MYH9	-899
KIF2C	-893
DYNLL2	-826
YWHAQ	-804
BIN1	-740
ZW10	-692
SEC24B	-641
GRB2	-640
IGHV3-48	-616
NAA35	-603
KIF15	-596
IGKV1-16	-593
AGPAT3	-576
MADD	-482
STAM	-473
SEC22B	-462
GABARAPL2	-456
COLEC11	-442
GCC1	-425
GJA4	-402
MAP1LC3B	-329
ARL1	-274
SYNJ2	-268
HIP1R	-172
GOLIM4	-170
HBB	-144
RAB4A	-45
REPS1	-43
HBA1	-36
CNIH3	18
FZD4	25
STX16	28
VTI1A	106
UBAP1	138
MIA3	162
AP4E1	209
COPS5	254
KIF25	262
KIF3C	332
KIF2A	345
DCTN4	354
YWHAB	461
NSF	470
EXOC4	475
VTA1	485
COL4A1	563
HSPH1	598
TRAPPC9	624
RAB9B	637
TBC1D24	654
IGHV3-23	658
CD3D	716
RAB43	737
DENND5A	740
UBQLN1	793
SPTB	806
VPS53	813
PPP6R3	842
SLC2A8	856
GJB2	882
STAB2	887
CLINT1	890
ANKRD28	968
JCHAIN	977
VPS4B	1107
ACBD3	1133
RAB6A	1159
SEC23IP	1219
ANK1	1261
EXOC1	1333
IGF2R	1365
COG3	1412
UBQLN2	1419
RAB6B	1445
PAFAH1B1	1455
MCFD2	1504
SBF2	1522
COG5	1530
FCHO1	1551
PACSIN3	1570
RHOQ	1590
DYNC1LI2	1641
TMED2	1655
ARF4	1701
AVP	1752
DENND3	1769
ARF6	1829
AGFG1	1901
ARPC3	1908
TBC1D1	1926
CYTH1	1958
RABEP1	1966
SYT2	2020
SPTBN4	2040
RAB36	2061
SNX18	2074
GOSR1	2105
SCFD1	2127
SPTBN2	2135
TPD52L1	2355
APOL1	2416
SAA1	2433
CFTR	2470
MAN1A1	2539
CHMP5	2563
STON1	2641
AP3S1	2651
NAPB	2662
SYT11	2679
YWHAZ	2683
VPS37A	2717
COG2	2766
LDLR	2820
SLC2A4	2822
TRAPPC4	2825
PRKAG2	2857
EXOC2	2908
KIF28P	2917
CNIH1	2956
DYNC1I1	2990
SCARF1	3012
SEC16B	3084
TGFA	3087
TRAPPC11	3147
AAK1	3166
PAFAH1B2	3188
HP	3247
SEC23A	3257
LNPEP	3277
TBC1D7	3283
TRAPPC8	3328
USP6NL	3385
VAMP4	3431
SEC24A	3440
RINT1	3511
DNAJC6	3533
COPS8	3577
CHMP4C	3607
YIPF6	3618
VPS36	3620
RALGAPA2	3693
BLOC1S6	3734
RHOBTB3	3779
IGKV1-33	3826
AKT3	3865
CAPZA1	3900
SCARB2	3918
RAB18	3942
GALNT1	3945
AP4S1	4102
ALS2CL	4109
DYNC1LI1	4123
GJD3	4130
COL7A1	4190
PPP6C	4218
MYO6	4306
TJP1	4348
VPS54	4402
TFRC	4407
F5	4416
GOLGA4	4425
KIF1B	4461
ALS2	4479
PICALM	4518
HPX	4539
PLA2G4A	4547
AP1G1	4550
RAB14	4562
NECAP1	4586
KIF21B	4633
ARPC5	4663
RAB11A	4666
BET1	4829
CBL	4864
ACTR3	4876
DENND4C	4897
PRKAB2	4901
VPS37B	4937
SNAP23	5022
WNT5A	5108
RIC1	5121
ACTR10	5159
CD36	5193
SAR1B	5213
GJC1	5222
MAN2A1	5224
RAB10	5228
CALM1	5275
TRAPPC6B	5307
KIF23	5308
ACTR2	5314
KIF19	5346
KIF26A	5404
TBC1D8B	5418
ITSN2	5420
TRAPPC2	5463
GCC2	5478
KIF3A	5503
TACR1	5505
MAN1A2	5512
EXOC6	5521
RALGAPB	5524
KIF27	5610
STX17	5615
GNS	5625
LMAN1	5694
TBC1D10C	5707
TMF1	5715
GAPVD1	5756
REPS2	5831
CHMP2B	5877
RAB30	5879
DENND5B	5931
STXBP3	5941
F8	5952
CD59	6007
SYTL1	6040
SPTBN5	6048
CLTCL1	6053
WASL	6108
TPD52	6139
VAMP7	6154
NAPG	6186
RAB3IP	6211
RAB3GAP2	6224
TBC1D4	6269
RAB33B	6319
RAB12	6337
NAA30	6351
USO1	6395
ADRB2	6428
TRIP11	6446
STAM2	6459
MIA2	6490
EXOC5	6534
KIF5B	6552
DENND1C	6568
RAB5A	6603
EPS15	6673
SCOC	6689
KIF6	6712
C2CD5	6823
CCZ1B	6866
CHM	6885
CLVS1	6938
FNBP1L	6950
TRAPPC13	6951
CAPZA2	6977
SYNJ1	6983
AP1S2	7001
COPS2	7016
DENND6A	7041
CENPE	7045
DENND4A	7055
SYT1	7118
ANK3	7258
COG6	7273
PRKAG3	7373
TBC1D15	7376
BICD1	7404
TMED7	7411
CD3G	7496
KIF21A	7519
DNM3	7676
EXOC8	7815
RAB21	7819
PIK3C2A	7865
KIF20B	7886
PRKAA2	8155
LRP2	8191
FCHO2	8292
EGF	8356
RAB8B	8371
SERPINA1	8375
CHML	8415
DENND2C	8529
AP1S3	8535
GJA1	8568
SGIP1	8656
RAB27A	8670
DENND1B	8790
KIF5C	8952
CPD	8968
HBEGF	9018
GRIA1	9317
AREG	9397
IL7R	9424

---

Cellular responses to stress

Cellular responses to stress

	180
set	Cellular responses to stress
setSize	663
pANOVA	3.71e-10
s.dist	-0.143
p.adjustANOVA	1.1e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2BC12	-9313
KDELR3	-9269
SOD3	-9234
CDKN2A	-9194
RPS4X	-9157
MAPK7	-9154
NUDT2	-9151
GPX3	-9149
AAAS	-9006
MYDGF	-8878
CXXC1	-8755
CRTC3	-8743
RPLP2	-8715
EXOSC7	-8626
CDK4	-8617
CUL7	-8598
VEGFA	-8586
RPL3	-8564
BLVRB	-8557
ARFGAP1	-8534

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2BC12	-9313
KDELR3	-9269
SOD3	-9234
CDKN2A	-9194
RPS4X	-9157
MAPK7	-9154
NUDT2	-9151
GPX3	-9149
AAAS	-9006
MYDGF	-8878
CXXC1	-8755
CRTC3	-8743
RPLP2	-8715
EXOSC7	-8626
CDK4	-8617
CUL7	-8598
VEGFA	-8586
RPL3	-8564
BLVRB	-8557
ARFGAP1	-8534
GPX8	-8517
HIRA	-8498
NOX4	-8461
SEC13	-8457
CRTC1	-8433
HMOX2	-8419
RPL23	-8406
CCS	-8358
RING1	-8331
EEF1A1	-8291
ACD	-8284
RPS14	-8278
SYVN1	-8265
RPS12	-8256
RPL36	-8166
SIN3B	-8136
RPL19	-8133
RPS28	-8128
DCTN1	-8089
KAT5	-8042
RPL28	-8031
EHMT1	-7986
WDR24	-7980
FKBP5	-7979
RPL37	-7930
EHMT2	-7911
RPS26	-7908
RPL31	-7842
ZBTB17	-7787
HDAC3	-7742
HDAC6	-7713
RPL26L1	-7694
NUP188	-7684
HM13	-7680
UBA52	-7643
RPS5	-7633
ATOX1	-7631
ANAPC2	-7619
PSMA7	-7617
FLCN	-7611
HYOU1	-7602
BLVRA	-7592
PSMB7	-7580
PSMC3	-7538
CRTC2	-7497
RPL13	-7472
RPS18	-7468
ITFG2	-7436
PTK6	-7428
EGLN2	-7418
RPL7A	-7394
RPS16	-7390
CSNK2B	-7373
RPS10	-7354
NUP85	-7351
RPA1	-7341
RPL26	-7340
NPRL3	-7295
RPL10A	-7253
STIP1	-7240
RPL30	-7217
DNAJA4	-7206
XBP1	-7192
LMNA	-7191
SURF1	-7160
GPX7	-7158
HDGF	-7157
SOD1	-7151
CREB3L4	-7141
RPS11	-7138
PSMD4	-7134
RPL4	-7127
FZR1	-7074
FAU	-7067
GSTP1	-7057
SEC31A	-7037
RPL13A	-7019
ADD1	-6998
ANAPC11	-6992
PSMC5	-6942
KHSRP	-6920
EIF2AK4	-6913
RPS17	-6903
CALR	-6854
EXOSC2	-6796
CTDSP2	-6776
RPS15	-6758
ARNT	-6740
RPL29	-6731
PRKCD	-6726
PSMD8	-6703
COX6A1	-6702
RPL36AL	-6668
LAMTOR4	-6648
CHAC1	-6624
TPP1	-6592
SRPRA	-6577
RPS20	-6537
MLST8	-6519
RPL38	-6495
RPL12	-6483
PSMB4	-6417
RPLP0	-6397
RPL10	-6333
LAMTOR2	-6311
RPL8	-6300
CAPZB	-6272
POM121	-6225
RPL5	-6221
EXOSC1	-6182
CABIN1	-6173
SERPINH1	-6168
WTIP	-6154
RPL37A	-6135
HSPA7	-6126
RPL27A	-6113
NCF4	-6110
SCMH1	-6109
SRPRB	-6094
CCAR2	-6067
WDR59	-6054
ATF5	-6015
YIF1A	-5995
MAPK3	-5987
ATP6V0B	-5977
NCOR2	-5973
RPS2	-5959
RPS8	-5958
DEDD2	-5941
ATP6V0D1	-5934
RPS21	-5899
GSK3A	-5880
RPL11	-5867
RPS27	-5866
RPLP1	-5846
RPS6	-5819
MBTPS1	-5783
SIN3A	-5782
PSMD9	-5765
DDIT3	-5758
VENTX	-5750
RPL17	-5749
RPL15	-5698
EP400	-5640
RPL32	-5598
NCOA6	-5597
HSP90AB1	-5567
NR1D1	-5554
PSMF1	-5494
CREBBP	-5487
DCTN2	-5482
CAT	-5467
RBBP7	-5415
RPL41	-5397
EIF2AK1	-5389
CREB3L2	-5361
RPL18	-5360
TRIB3	-5342
EXOSC4	-5333
PSMB3	-5327
RPS19BP1	-5286
ELOB	-5284
LIMD1	-5277
COX19	-5259
RPL23A	-5246
PSMD3	-5235
RRAGB	-5194
PSMB1	-5182
RPL34	-5148
P4HB	-5094
PSMD7	-5070
TFDP2	-5065
CREB3	-5063
RPL7	-5057
TACO1	-5034
MAP2K7	-5020
TCIRG1	-5017
RPL18A	-5015
ID1	-4991
PSMD14	-4951
PSMB10	-4948
RPL6	-4942
RPS23	-4940
DCTN5	-4917
WIPI1	-4916
PSMC2	-4880
PSMB6	-4849
RPS19	-4848
RXRA	-4843
RPS3	-4842
COX14	-4833
TLN1	-4831
ACTR1A	-4804
HMOX1	-4801
HSPA5	-4787
LAMTOR1	-4755
PSMD2	-4715
ATP6V1F	-4696
VCP	-4638
NUP62	-4588
PSMA1	-4587
PARN	-4578
RPL14	-4555
CDC26	-4540
CREB3L1	-4532
TPR	-4504
WFS1	-4496
GOSR2	-4481
DYNC1H1	-4438
ATP6V1B1	-4396
PSMA5	-4364
CSNK2A2	-4363
CBX6	-4362
PSMD10	-4338
HSF1	-4337
CBX2	-4279
PSMD1	-4278
MTOR	-4239
ATP6V1E1	-4236
KEAP1	-4234
TNFRSF21	-4228
NUP214	-4176
RPS15A	-4165
DYNC1I2	-4164
DCTN3	-4136
ST13	-4094
DYNLL1	-4027
HSPA8	-3981
RPL27	-3935
PRDX6	-3904
TINF2	-3869
CUL1	-3857
RAE1	-3807
KPTN	-3800
RPL35	-3792
CDC16	-3785
HSPA12B	-3750
HERPUD1	-3748
KLHDC3	-3726
RAI1	-3721
AR	-3719
RPL39L	-3699
NUP88	-3689
H2AJ	-3688
POM121C	-3677
PRDX5	-3645
RBX1	-3643
ANAPC5	-3632
MAPK9	-3625
GCN1	-3595
CYBB	-3575
TXNIP	-3546
TATDN2	-3540
RPL39	-3539
NFKB1	-3526
PSMC4	-3510
RRAGA	-3479
TXN2	-3453
RPTOR	-3421
ATP6V0C	-3416
ATP6V0E1	-3412
NUP98	-3400
MED1	-3350
SESN2	-3316
UBN1	-3296
EIF2S2	-3286
RPS9	-3253
DEPDC5	-3238
PSMB2	-3187
EXOSC5	-3179
NCOR1	-3170
GRB10	-3165
NUP93	-3163
RPS24	-3138
TP53	-3110
TXNRD2	-3083
RPS29	-3082
RELA	-3015
NUP43	-2946
BAG5	-2863
DNAJB11	-2847
TERF2	-2837
UBB	-2810
MAP4K4	-2790
COX4I1	-2771
HSP90AA1	-2745
PHC2	-2703
DDX11	-2637
UBC	-2608
NPAS2	-2583
CDKN2B	-2581
PSMD6	-2563
EXOSC3	-2536
APOB	-2510
PSMB5	-2492
MOV10	-2486
E2F1	-2460
PSMD13	-2447
BAG1	-2401
DNAJB1	-2393
SERP1	-2337
NPRL2	-2310
HSP90B1	-2260
HMGA1	-2228
DNAJC7	-2158
RRAGC	-2106
ATP6V1E2	-2095
CARM1	-2078
DCTN6	-2064
RPS27A	-2058
COX6B1	-2050
PDIA6	-2048
DNAJA2	-2036
AKT1S1	-2032
CYBA	-1998
MAP2K3	-1950
TNRC6A	-1927
COX7C	-1852
EXOSC6	-1847
RPL35A	-1829
NCOA1	-1812
COX11	-1766
COX8A	-1726
TBL1X	-1706
PPARA	-1702
PSME3	-1691
MAFK	-1646
YWHAE	-1609
MAPKAPK2	-1543
MAPK10	-1534
MINK1	-1441
SLC46A1	-1435
PLA2G4B	-1431
ATF4	-1387
COX6C	-1378
CDC23	-1342
EP300	-1330
ABCC1	-1307
FKBP4	-1306
NOX5	-1292
SCO1	-1284
PSMC1	-1275
RPA2	-1274
SULT1A3	-1264
MAPKAPK5	-1263
ANAPC10	-1260
LAMTOR5	-1245
RPS4Y1	-1198
AGO1	-1167
ATP6V1D	-1140
EXTL3	-1063
H2AZ2	-1025
RPS6KA2	-1000
ANAPC7	-994
HSPA4	-967
TFDP1	-937
PREB	-921
PRDX1	-900
TERF2IP	-883
SZT2	-879
ATP6V1H	-876
DYNLL2	-826
EZH2	-801
STAT3	-775
SEM1	-739
SH3BP4	-696
PSME1	-634
HIF1AN	-621
CUL2	-617
HSBP1	-591
PSMA2	-550
RPS25	-545
EIF2AK3	-445
RPL21	-383
CRYAB	-382
PSMD11	-353
PSMB8	-350
RPS3A	-334
NFYC	-309
RPS13	-295
GFPT1	-256
PPP2R5B	-200
COX7B	-174
MEF2D	-162
CDKN2D	-160
RPSA	-148
HBB	-144
H2AZ1	-107
HIF3A	-98
ACADVL	-74
EIF2S3	-66
ATP6V0E2	-60
NUP155	-51
SP1	-44
HBA1	-36
EGLN3	-35
ERF	30
ATP6V1C1	38
ATF6	41
NRIP1	143
SHC1	228
TXN	237
CAMK2G	277
NUP42	299
CEBPG	329
IGFBP7	330
DNAJB6	344
DCTN4	354
COX5B	415
TNIK	468
HSPA1L	502
MAPK1	583
HSPH1	598
PSME4	609
SKP1	657
EPAS1	697
EDEM1	719
SESN1	726
NUP205	808
CCNA2	814
IMPACT	880
MRPL18	949
COX18	993
MAP3K5	996
ANAPC4	1002
EXTL1	1032
SSR1	1039
E2F2	1064
ATP6V1G1	1079
CITED2	1095
MAPKAPK3	1123
RPA3	1184
RPS7	1197
PDIA5	1231
ANAPC1	1233
RPS27L	1251
RPL22	1273
RPL24	1297
GSR	1306
BAG2	1340
NUP210	1376
PRDX3	1391
TSPYL2	1458
MAPK11	1544
ELOC	1560
NUP153	1582
PSMA6	1616
DYNC1LI2	1641
NUP160	1654
ANAPC16	1658
CSNK2A1	1672
PSMA3	1706
RBBP4	1776
MAP2K4	1833
RHEB	1848
PSMC6	1856
EXTL2	1874
RRAGD	1883
ATP6V1G2	1889
COX5A	1913
PRDX2	1934
EXOSC9	1963
NCF1	2059
TLR4	2073
NFE2L2	2107
CBX8	2109
CCNE1	2155
CDKN2C	2287
NUP54	2334
TGS1	2340
MAPK14	2383
TXNRD1	2385
POT1	2392
EED	2399
BAG3	2438
CBX4	2465
ANAPC15	2487
DIS3	2583
MIOS	2598
HSPA1A	2615
NUP35	2637
EXOSC8	2653
COX20	2734
HELZ2	2739
GPX1	2781
PHC1	2838
HSPA2	2846
H1-0	2872
VHL	2927
CUL3	2930
ARNTL	2989
DYNC1I1	2990
DNAJA1	3014
HIKESHI	3045
DNAJC2	3050
COL4A6	3093
HSPA12A	3143
PSMD5	3165
ERO1A	3167
LAMTOR3	3279
PSME2	3291
ASNS	3352
HSPA9	3399
NDUFA4	3446
HSPA6	3447
UBE2D2	3489
SCO2	3548
HSPA1B	3653
RAD50	3666
SMARCD3	3724
NFYB	3729
RPL3L	3763
TNRC6C	3778
UBE2S	3867
CAPZA1	3900
DNAJC3	3962
CHD9	4007
TNRC6B	4009
EIF2S1	4031
PGR	4035
PSMA4	4076
DYNC1LI1	4123
HSPA14	4142
CAMK2B	4151
PPARGC1A	4165
EGLN1	4178
CDKN1B	4182
PSMB9	4260
MT-CO1	4282
MT-CO2	4296
AGO4	4372
LRPPRC	4414
CAMK2A	4415
STAP2	4478
COX7A2L	4527
PSMD12	4558
RPS6KA1	4595
H2BC5	4656
ATP6V1B2	4684
NDC1	4688
CCNE2	4691
MAPK8	4720
NUP133	4739
MBTPS2	4743
UBE2E1	4757
MRE11	4776
NCF2	4807
MDM4	4928
NBN	4936
NUP107	4939
AJUBA	5030
FNIP1	5034
RANBP2	5097
FKBP14	5102
DNAJB9	5137
BMI1	5138
KDM6B	5145
ACTR10	5159
MAP2K6	5310
MDM2	5328
TBL1XR1	5336
RPS6KA3	5364
RNF2	5423
ATR	5455
MEF2C	5518
SIRT1	5583
CAMK2D	5590
FNIP2	5636
CREB1	5680
NUP37	5735
PTGES3	5736
NR3C1	5752
NUP50	5855
NFYA	5867
HSPB8	5898
FBXL17	5961
SEH1L	6077
PHC3	6083
ATP6V1C2	6141
UBE2D3	6151
RPL9	6370
HSPA4L	6385
AGO3	6396
E2F3	6435
GSK3B	6450
H2BC4	6513
CDC27	6566
H3-3A	6579
RPL22L1	6595
UBE2D1	6734
ATP6V1A	6744
NLRP3	6794
ERN1	6857
SLC38A9	6874
RPL36A	6879
CEBPB	6914
CLOCK	6976
CAPZA2	6977
HSPA13	6995
SKP2	7003
BAG4	7004
DCP2	7085
NR3C2	7119
CYCS	7197
BACH1	7263
HIGD1A	7309
ASF1A	7313
XPO1	7330
H1-2	7353
ATF2	7424
DCSTAMP	7436
ATM	7528
ATP6V0D2	7571
CDK6	7579
TERF1	7595
BMT2	7603
SOD2	7796
SUZ12	7927
LMNB1	7977
MT-CO3	8009
COX16	8068
CREBRF	8242
ETS2	8274
H2AC18	8329
ETS1	8357
RB1	8392
HIF1A	8395
ATP7A	8404
LY96	8522
NCOA2	8533
CDK2	8654
PPP1R15A	8698
NUP58	8794
H2BC21	8851
RORA	8950
H2AC6	8988
JUN	9070
CDKN1A	9222
ATF3	9275
FOS	9429
IL6	9444
CCL2	9454
CXCL8	9469

---

Cellular responses to stimuli

Cellular responses to stimuli

	179
set	Cellular responses to stimuli
setSize	671
pANOVA	7.74e-10
s.dist	-0.139
p.adjustANOVA	2.25e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2BC12	-9313
KDELR3	-9269
SOD3	-9234
CDKN2A	-9194
RPS4X	-9157
MAPK7	-9154
NUDT2	-9151
GPX3	-9149
AAAS	-9006
MYDGF	-8878
CXXC1	-8755
CRTC3	-8743
RPLP2	-8715
EXOSC7	-8626
CDK4	-8617
CUL7	-8598
VEGFA	-8586
RPL3	-8564
BLVRB	-8557
ARFGAP1	-8534

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2BC12	-9313
KDELR3	-9269
SOD3	-9234
CDKN2A	-9194
RPS4X	-9157
MAPK7	-9154
NUDT2	-9151
GPX3	-9149
AAAS	-9006
MYDGF	-8878
CXXC1	-8755
CRTC3	-8743
RPLP2	-8715
EXOSC7	-8626
CDK4	-8617
CUL7	-8598
VEGFA	-8586
RPL3	-8564
BLVRB	-8557
ARFGAP1	-8534
GPX8	-8517
HIRA	-8498
NOX4	-8461
SEC13	-8457
CRTC1	-8433
HMOX2	-8419
RPL23	-8406
CCS	-8358
RING1	-8331
EEF1A1	-8291
ACD	-8284
RPS14	-8278
SYVN1	-8265
RPS12	-8256
RPL36	-8166
SIN3B	-8136
RPL19	-8133
RPS28	-8128
DCTN1	-8089
KAT5	-8042
RPL28	-8031
EHMT1	-7986
WDR24	-7980
FKBP5	-7979
RPL37	-7930
EHMT2	-7911
RPS26	-7908
RPL31	-7842
ZBTB17	-7787
HDAC3	-7742
HDAC6	-7713
RPL26L1	-7694
NUP188	-7684
HM13	-7680
UBA52	-7643
RPS5	-7633
ATOX1	-7631
ANAPC2	-7619
PSMA7	-7617
FLCN	-7611
HYOU1	-7602
BLVRA	-7592
PSMB7	-7580
PSMC3	-7538
CRTC2	-7497
RPL13	-7472
RPS18	-7468
ITFG2	-7436
PTK6	-7428
EGLN2	-7418
RPL7A	-7394
RPS16	-7390
CSNK2B	-7373
RPS10	-7354
NUP85	-7351
RPA1	-7341
RPL26	-7340
NPRL3	-7295
RPL10A	-7253
STIP1	-7240
RPL30	-7217
DNAJA4	-7206
XBP1	-7192
LMNA	-7191
SURF1	-7160
GPX7	-7158
HDGF	-7157
SOD1	-7151
CREB3L4	-7141
RPS11	-7138
PSMD4	-7134
RPL4	-7127
FZR1	-7074
FAU	-7067
GSTP1	-7057
SEC31A	-7037
RPL13A	-7019
ADD1	-6998
ANAPC11	-6992
PSMC5	-6942
KHSRP	-6920
EIF2AK4	-6913
RPS17	-6903
CALR	-6854
EXOSC2	-6796
CTDSP2	-6776
RPS15	-6758
ARNT	-6740
RPL29	-6731
PRKCD	-6726
PSMD8	-6703
COX6A1	-6702
RPL36AL	-6668
LAMTOR4	-6648
CHAC1	-6624
TPP1	-6592
SRPRA	-6577
RPS20	-6537
MLST8	-6519
RPL38	-6495
RPL12	-6483
PSMB4	-6417
RPLP0	-6397
RPL10	-6333
LAMTOR2	-6311
RPL8	-6300
CAPZB	-6272
POM121	-6225
RPL5	-6221
EXOSC1	-6182
CABIN1	-6173
SERPINH1	-6168
WTIP	-6154
RPL37A	-6135
HSPA7	-6126
RPL27A	-6113
NCF4	-6110
SCMH1	-6109
SRPRB	-6094
CCAR2	-6067
WDR59	-6054
ATF5	-6015
YIF1A	-5995
MAPK3	-5987
ATP6V0B	-5977
NCOR2	-5973
RPS2	-5959
RPS8	-5958
DEDD2	-5941
ATP6V0D1	-5934
RPS21	-5899
GSK3A	-5880
RPL11	-5867
RPS27	-5866
RPLP1	-5846
RPS6	-5819
MBTPS1	-5783
SIN3A	-5782
PSMD9	-5765
DDIT3	-5758
VENTX	-5750
RPL17	-5749
RPL15	-5698
EP400	-5640
RPL32	-5598
NCOA6	-5597
HSP90AB1	-5567
NR1D1	-5554
PSMF1	-5494
CREBBP	-5487
DCTN2	-5482
CAT	-5467
RBBP7	-5415
RPL41	-5397
EIF2AK1	-5389
CREB3L2	-5361
RPL18	-5360
TRIB3	-5342
EXOSC4	-5333
PSMB3	-5327
RPS19BP1	-5286
ELOB	-5284
LIMD1	-5277
COX19	-5259
RPL23A	-5246
PSMD3	-5235
RRAGB	-5194
PSMB1	-5182
RPL34	-5148
MT1E	-5108
P4HB	-5094
PSMD7	-5070
TFDP2	-5065
CREB3	-5063
RPL7	-5057
TACO1	-5034
MAP2K7	-5020
TCIRG1	-5017
RPL18A	-5015
ID1	-4991
PSMD14	-4951
PSMB10	-4948
RPL6	-4942
RPS23	-4940
DCTN5	-4917
WIPI1	-4916
PSMC2	-4880
PSMB6	-4849
RPS19	-4848
RXRA	-4843
RPS3	-4842
COX14	-4833
TLN1	-4831
ACTR1A	-4804
HMOX1	-4801
HSPA5	-4787
LAMTOR1	-4755
PSMD2	-4715
ATP6V1F	-4696
VCP	-4638
NUP62	-4588
PSMA1	-4587
PARN	-4578
RPL14	-4555
CDC26	-4540
CREB3L1	-4532
TPR	-4504
WFS1	-4496
GOSR2	-4481
DYNC1H1	-4438
ATP6V1B1	-4396
PSMA5	-4364
CSNK2A2	-4363
CBX6	-4362
PSMD10	-4338
HSF1	-4337
CBX2	-4279
PSMD1	-4278
MTOR	-4239
ATP6V1E1	-4236
KEAP1	-4234
TNFRSF21	-4228
NUP214	-4176
RPS15A	-4165
DYNC1I2	-4164
DCTN3	-4136
ST13	-4094
DYNLL1	-4027
HSPA8	-3981
RPL27	-3935
PRDX6	-3904
TINF2	-3869
CUL1	-3857
RAE1	-3807
KPTN	-3800
RPL35	-3792
CDC16	-3785
HSPA12B	-3750
HERPUD1	-3748
KLHDC3	-3726
RAI1	-3721
AR	-3719
RPL39L	-3699
NUP88	-3689
H2AJ	-3688
POM121C	-3677
PRDX5	-3645
RBX1	-3643
ANAPC5	-3632
MAPK9	-3625
GCN1	-3595
CYBB	-3575
TXNIP	-3546
TATDN2	-3540
RPL39	-3539
NFKB1	-3526
PSMC4	-3510
RRAGA	-3479
TXN2	-3453
RPTOR	-3421
ATP6V0C	-3416
ATP6V0E1	-3412
NUP98	-3400
MED1	-3350
SESN2	-3316
UBN1	-3296
EIF2S2	-3286
RPS9	-3253
DEPDC5	-3238
PSMB2	-3187
EXOSC5	-3179
NCOR1	-3170
GRB10	-3165
NUP93	-3163
RPS24	-3138
TP53	-3110
TXNRD2	-3083
RPS29	-3082
RELA	-3015
NUP43	-2946
BAG5	-2863
DNAJB11	-2847
TERF2	-2837
UBB	-2810
MAP4K4	-2790
COX4I1	-2771
HSP90AA1	-2745
PHC2	-2703
DDX11	-2637
UBC	-2608
NPAS2	-2583
CDKN2B	-2581
PSMD6	-2563
EXOSC3	-2536
APOB	-2510
PSMB5	-2492
MOV10	-2486
E2F1	-2460
PSMD13	-2447
BAG1	-2401
DNAJB1	-2393
SERP1	-2337
NPRL2	-2310
HSP90B1	-2260
HMGA1	-2228
DNAJC7	-2158
RRAGC	-2106
ATP6V1E2	-2095
CARM1	-2078
DCTN6	-2064
RPS27A	-2058
MT1F	-2055
COX6B1	-2050
PDIA6	-2048
DNAJA2	-2036
AKT1S1	-2032
CYBA	-1998
MAP2K3	-1950
TNRC6A	-1927
COX7C	-1852
EXOSC6	-1847
RPL35A	-1829
NCOA1	-1812
COX11	-1766
COX8A	-1726
TBL1X	-1706
PPARA	-1702
PSME3	-1691
MT1X	-1663
MAFK	-1646
YWHAE	-1609
MAPKAPK2	-1543
MAPK10	-1534
MINK1	-1441
SLC46A1	-1435
PLA2G4B	-1431
ATF4	-1387
COX6C	-1378
CSRP1	-1367
CDC23	-1342
EP300	-1330
ABCC1	-1307
FKBP4	-1306
NOX5	-1292
SCO1	-1284
PSMC1	-1275
RPA2	-1274
SULT1A3	-1264
MAPKAPK5	-1263
ANAPC10	-1260
LAMTOR5	-1245
RPS4Y1	-1198
AGO1	-1167
ATP6V1D	-1140
EXTL3	-1063
H2AZ2	-1025
RPS6KA2	-1000
ANAPC7	-994
HSPA4	-967
TFDP1	-937
PREB	-921
PRDX1	-900
TERF2IP	-883
SZT2	-879
ATP6V1H	-876
DYNLL2	-826
EZH2	-801
STAT3	-775
SEM1	-739
SH3BP4	-696
PSME1	-634
HIF1AN	-621
CUL2	-617
HSBP1	-591
PSMA2	-550
RPS25	-545
EIF2AK3	-445
RPL21	-383
CRYAB	-382
PSMD11	-353
PSMB8	-350
RPS3A	-334
NFYC	-309
RPS13	-295
GFPT1	-256
PPP2R5B	-200
COX7B	-174
MEF2D	-162
CDKN2D	-160
RPSA	-148
HBB	-144
H2AZ1	-107
HIF3A	-98
ACADVL	-74
EIF2S3	-66
ATP6V0E2	-60
NUP155	-51
SP1	-44
HBA1	-36
EGLN3	-35
ERF	30
ATP6V1C1	38
ATF6	41
NRIP1	143
SHC1	228
TXN	237
CAMK2G	277
NUP42	299
CEBPG	329
IGFBP7	330
DNAJB6	344
DCTN4	354
COX5B	415
TNIK	468
HSPA1L	502
MTF1	574
MAPK1	583
HSPH1	598
PSME4	609
SKP1	657
EPAS1	697
EDEM1	719
SESN1	726
NUP205	808
CCNA2	814
IMPACT	880
MRPL18	949
COX18	993
MAP3K5	996
ANAPC4	1002
EXTL1	1032
SSR1	1039
E2F2	1064
ATP6V1G1	1079
CITED2	1095
MAPKAPK3	1123
RPA3	1184
RPS7	1197
PDIA5	1231
ANAPC1	1233
RPS27L	1251
RPL22	1273
RPL24	1297
GSR	1306
BAG2	1340
NUP210	1376
PRDX3	1391
TSPYL2	1458
MAPK11	1544
ELOC	1560
NUP153	1582
PSMA6	1616
DYNC1LI2	1641
NUP160	1654
ANAPC16	1658
CSNK2A1	1672
PSMA3	1706
RBBP4	1776
MAP2K4	1833
RHEB	1848
PSMC6	1856
EXTL2	1874
RRAGD	1883
ATP6V1G2	1889
COX5A	1913
PRDX2	1934
EXOSC9	1963
NCF1	2059
TLR4	2073
NFE2L2	2107
CBX8	2109
CCNE1	2155
CDKN2C	2287
NUP54	2334
TGS1	2340
MAPK14	2383
TXNRD1	2385
POT1	2392
EED	2399
BAG3	2438
CBX4	2465
ANAPC15	2487
DIS3	2583
MIOS	2598
HSPA1A	2615
NUP35	2637
EXOSC8	2653
COX20	2734
HELZ2	2739
GPX1	2781
PHC1	2838
HSPA2	2846
H1-0	2872
VHL	2927
CUL3	2930
ARNTL	2989
DYNC1I1	2990
DNAJA1	3014
HIKESHI	3045
DNAJC2	3050
COL4A6	3093
HSPA12A	3143
PSMD5	3165
ERO1A	3167
LAMTOR3	3279
PSME2	3291
ASNS	3352
HSPA9	3399
NDUFA4	3446
HSPA6	3447
UBE2D2	3489
SCO2	3548
HSPA1B	3653
RAD50	3666
SMARCD3	3724
NFYB	3729
RPL3L	3763
TNRC6C	3778
UBE2S	3867
CAPZA1	3900
DNAJC3	3962
CHD9	4007
TNRC6B	4009
EIF2S1	4031
PGR	4035
PSMA4	4076
DYNC1LI1	4123
HSPA14	4142
CAMK2B	4151
PPARGC1A	4165
EGLN1	4178
CDKN1B	4182
PSMB9	4260
MT-CO1	4282
MT-CO2	4296
AGO4	4372
LRPPRC	4414
CAMK2A	4415
STAP2	4478
COX7A2L	4527
PSMD12	4558
RPS6KA1	4595
H2BC5	4656
ATP6V1B2	4684
NDC1	4688
CCNE2	4691
MAPK8	4720
NUP133	4739
MBTPS2	4743
UBE2E1	4757
MRE11	4776
NCF2	4807
MDM4	4928
NBN	4936
NUP107	4939
AJUBA	5030
FNIP1	5034
RANBP2	5097
FKBP14	5102
DNAJB9	5137
BMI1	5138
KDM6B	5145
ACTR10	5159
MAP2K6	5310
MDM2	5328
TBL1XR1	5336
RPS6KA3	5364
MT1M	5393
RNF2	5423
ATR	5455
MEF2C	5518
SIRT1	5583
CAMK2D	5590
FNIP2	5636
CREB1	5680
MT2A	5721
NUP37	5735
PTGES3	5736
NR3C1	5752
NUP50	5855
NFYA	5867
HSPB8	5898
FBXL17	5961
SEH1L	6077
PHC3	6083
ATP6V1C2	6141
UBE2D3	6151
RPL9	6370
HSPA4L	6385
AGO3	6396
E2F3	6435
GSK3B	6450
H2BC4	6513
CDC27	6566
H3-3A	6579
RPL22L1	6595
UBE2D1	6734
ATP6V1A	6744
NLRP3	6794
ERN1	6857
SLC38A9	6874
RPL36A	6879
CEBPB	6914
CLOCK	6976
CAPZA2	6977
HSPA13	6995
SKP2	7003
BAG4	7004
DCP2	7085
NR3C2	7119
CYCS	7197
BACH1	7263
HIGD1A	7309
ASF1A	7313
XPO1	7330
H1-2	7353
ATF2	7424
DCSTAMP	7436
ATM	7528
ATP6V0D2	7571
CDK6	7579
TERF1	7595
BMT2	7603
SOD2	7796
SUZ12	7927
LMNB1	7977
MT-CO3	8009
COX16	8068
CREBRF	8242
ETS2	8274
H2AC18	8329
ETS1	8357
RB1	8392
HIF1A	8395
ATP7A	8404
LY96	8522
NCOA2	8533
CDK2	8654
PPP1R15A	8698
NUP58	8794
H2BC21	8851
RORA	8950
H2AC6	8988
JUN	9070
MT1A	9183
CDKN1A	9222
ATF3	9275
FOS	9429
IL6	9444
CCL2	9454
CXCL8	9469

---

Here is the session info with all the versions of packages used.

sessionInfo()

## R version 4.2.0 (2022-04-22)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 20.04.4 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.9.0
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.9.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.2.4               GGally_2.1.2               
##  [3] beeswarm_0.4.0              gtools_3.9.2               
##  [5] echarts4r_0.4.3             kableExtra_1.3.4           
##  [7] topconfects_1.8.0           limma_3.48.3               
##  [9] eulerr_6.1.1                mitch_1.4.1                
## [11] MASS_7.3-56                 fgsea_1.18.0               
## [13] gplots_3.1.1                DESeq2_1.32.0              
## [15] SummarizedExperiment_1.22.0 Biobase_2.52.0             
## [17] MatrixGenerics_1.4.3        matrixStats_0.61.0         
## [19] GenomicRanges_1.44.0        GenomeInfoDb_1.28.4        
## [21] IRanges_2.26.0              S4Vectors_0.30.2           
## [23] BiocGenerics_0.38.0         reshape2_1.4.4             
## [25] forcats_0.5.1               stringr_1.4.0              
## [27] dplyr_1.0.8                 purrr_0.3.4                
## [29] readr_2.1.2                 tidyr_1.2.0                
## [31] tibble_3.1.6                ggplot2_3.3.5              
## [33] tidyverse_1.3.1             zoo_1.8-9                  
## 
## loaded via a namespace (and not attached):
##   [1] colorspace_2.0-3       ellipsis_0.3.2         rprojroot_2.0.2       
##   [4] XVector_0.32.0         fs_1.5.2               rstudioapi_0.13       
##   [7] bit64_4.0.5            AnnotationDbi_1.54.1   fansi_1.0.2           
##  [10] lubridate_1.8.0        xml2_1.3.3             splines_4.2.0         
##  [13] cachem_1.0.6           geneplotter_1.70.0     knitr_1.37            
##  [16] jsonlite_1.8.0         broom_0.7.12           annotate_1.70.0       
##  [19] dbplyr_2.1.1           png_0.1-7              shiny_1.7.1           
##  [22] compiler_4.2.0         httr_1.4.2             backports_1.4.1       
##  [25] assertthat_0.2.1       Matrix_1.4-1           fastmap_1.1.0         
##  [28] cli_3.2.0              later_1.3.0            htmltools_0.5.2       
##  [31] tools_4.2.0            gtable_0.3.0           glue_1.6.2            
##  [34] GenomeInfoDbData_1.2.6 fastmatch_1.1-3        Rcpp_1.0.8.2          
##  [37] cellranger_1.1.0       jquerylib_0.1.4        vctrs_0.3.8           
##  [40] Biostrings_2.60.2      svglite_2.1.0          xfun_0.30             
##  [43] rvest_1.0.2            mime_0.12              lifecycle_1.0.1       
##  [46] XML_3.99-0.9           zlibbioc_1.38.0        scales_1.1.1          
##  [49] promises_1.2.0.1       hms_1.1.1              RColorBrewer_1.1-2    
##  [52] yaml_2.3.5             gridExtra_2.3          memoise_2.0.1         
##  [55] sass_0.4.0             reshape_0.8.8          stringi_1.7.6         
##  [58] RSQLite_2.2.10         highr_0.9              genefilter_1.74.1     
##  [61] desc_1.4.1             caTools_1.18.2         BiocParallel_1.26.2   
##  [64] systemfonts_1.0.4      rlang_1.0.2            pkgconfig_2.0.3       
##  [67] bitops_1.0-7           evaluate_0.15          lattice_0.20-45       
##  [70] htmlwidgets_1.5.4      bit_4.0.4              tidyselect_1.1.2      
##  [73] plyr_1.8.6             magrittr_2.0.2         R6_2.5.1              
##  [76] generics_0.1.2         DelayedArray_0.18.0    DBI_1.1.2             
##  [79] pillar_1.7.0           haven_2.4.3            withr_2.5.0           
##  [82] survival_3.3-1         KEGGREST_1.32.0        RCurl_1.98-1.6        
##  [85] modelr_0.1.8           crayon_1.5.0           KernSmooth_2.23-20    
##  [88] utf8_1.2.2             tzdb_0.2.0             rmarkdown_2.13        
##  [91] locfit_1.5-9.5         grid_4.2.0             readxl_1.3.1          
##  [94] data.table_1.14.2      blob_1.2.2             webshot_0.5.2         
##  [97] reprex_2.0.1           digest_0.6.29          xtable_1.8-4          
## [100] httpuv_1.6.5           munsell_0.5.0          viridisLite_0.4.0     
## [103] bslib_0.3.1

END of report