Mitch Report
Antony Kaspi & Mark Ziemann
date generated: 2022-05-11
Background
Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch
Input profiles
Here is the first few lines of the input profile.
## x
## 5_8S_rRNA 0.18863167
## A1BG 1.99146833
## A1BG-AS1 1.15212281
## A2M 1.63641745
## A2M-AS1 -0.06500128
## A4GALT 0.47986302| Profile metrics | |
|---|---|
| num_genesets | 2512 |
| num_genes_in_profile | 19327 |
| duplicated_genes_present | 0 |
| num_profile_genes_in_sets | 8748 |
| num_profile_genes_not_in_sets | 10579 |
Here is a plot of the input profiles. Note the dynamic ranges. 
Here is the contour plot of the profile including all detected genes.
Input genesets
Here are some metrics about the gene sets used: GMT file of genesets: ReactomePathways.gmt| Gene sets metrics | |
|---|---|
| num_genesets | 2512 |
| num_genesets_excluded | 1061 |
| num_genesets_included | 1451 |
Differential pathway expression
Interactive enrichment scatterplot
Significance is calculated by -log10(p-value). All points shown are FDR<0.05.
Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.
Results table
Top N= 50 gene sets| set | setSize | pANOVA | s.dist | p.adjustANOVA |
|---|---|---|---|---|
| Metabolism | 1829 | 9.99e-42 | -0.192 | 1.45e-38 |
| Innate Immune System | 939 | 3.77e-39 | -0.252 | 2.74e-36 |
| Metabolism of proteins | 1695 | 7.22e-32 | -0.172 | 3.49e-29 |
| Immune System | 1744 | 3.01e-30 | -0.165 | 1.09e-27 |
| Disease | 1446 | 2.05e-29 | -0.177 | 5.94e-27 |
| Classical antibody-mediated complement activation | 45 | 2.25e-27 | -0.933 | 5.45e-25 |
| FCGR activation | 52 | 5.76e-26 | -0.844 | 1.19e-23 |
| Initial triggering of complement | 57 | 8.45e-26 | -0.803 | 1.53e-23 |
| Infectious disease | 761 | 4.75e-25 | -0.220 | 7.66e-23 |
| Creation of C4 and C2 activators | 50 | 9.05e-25 | -0.839 | 1.31e-22 |
| CD22 mediated BCR regulation | 43 | 1.18e-24 | -0.902 | 1.55e-22 |
| Neutrophil degranulation | 441 | 4.05e-24 | -0.281 | 4.90e-22 |
| Regulation of Complement cascade | 74 | 1.25e-23 | -0.673 | 1.40e-21 |
| Translation | 294 | 6.15e-23 | -0.334 | 6.37e-21 |
| Complement cascade | 81 | 1.71e-22 | -0.627 | 1.66e-20 |
| Role of LAT2/NTAL/LAB on calcium mobilization | 49 | 3.31e-22 | -0.799 | 3.00e-20 |
| Scavenging of heme from plasma | 46 | 6.14e-22 | -0.820 | 5.24e-20 |
| FCGR3A-mediated phagocytosis | 99 | 2.73e-21 | -0.550 | 1.98e-19 |
| Leishmania phagocytosis | 99 | 2.73e-21 | -0.550 | 1.98e-19 |
| Parasite infection | 99 | 2.73e-21 | -0.550 | 1.98e-19 |
| Regulation of actin dynamics for phagocytic cup formation | 101 | 6.07e-21 | -0.540 | 4.19e-19 |
| Role of phospholipids in phagocytosis | 64 | 6.61e-20 | -0.660 | 4.36e-18 |
| Fcgamma receptor (FCGR) dependent phagocytosis | 125 | 7.65e-20 | -0.472 | 4.83e-18 |
| Adaptive Immune System | 718 | 1.88e-19 | -0.198 | 1.14e-17 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | 68 | 2.89e-19 | -0.629 | 1.68e-17 |
| Asparagine N-linked glycosylation | 274 | 5.99e-19 | -0.312 | 3.22e-17 |
| Vesicle-mediated transport | 644 | 5.99e-19 | -0.206 | 3.22e-17 |
| FCERI mediated NF-kB activation | 112 | 1.61e-18 | -0.480 | 8.32e-17 |
| The citric acid (TCA) cycle and respiratory electron transport | 172 | 1.95e-18 | -0.387 | 9.76e-17 |
| Signaling by the B Cell Receptor (BCR) | 146 | 3.89e-18 | -0.416 | 1.88e-16 |
| Binding and Uptake of Ligands by Scavenger Receptors | 74 | 1.62e-17 | -0.572 | 7.59e-16 |
| Post-translational protein modification | 1230 | 2.98e-17 | -0.144 | 1.35e-15 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | 140 | 3.89e-17 | -0.412 | 1.71e-15 |
| Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | 125 | 8.30e-17 | -0.431 | 3.54e-15 |
| FCGR3A-mediated IL10 synthesis | 77 | 1.36e-16 | -0.545 | 5.63e-15 |
| Metabolism of carbohydrates | 265 | 4.56e-16 | -0.290 | 1.84e-14 |
| Mitochondrial translation elongation | 90 | 1.66e-15 | -0.485 | 6.51e-14 |
| Mitochondrial translation initiation | 90 | 1.46e-14 | -0.469 | 5.59e-13 |
| Fc epsilon receptor (FCERI) signaling | 165 | 1.66e-14 | -0.346 | 6.19e-13 |
| FCERI mediated Ca+2 mobilization | 64 | 2.01e-14 | -0.553 | 7.29e-13 |
| Cellular responses to stimuli | 676 | 3.22e-14 | -0.171 | 1.14e-12 |
| Mitochondrial translation termination | 90 | 7.49e-14 | -0.456 | 2.59e-12 |
| Diseases of metabolism | 209 | 9.33e-14 | -0.299 | 3.15e-12 |
| Mitochondrial translation | 96 | 1.08e-13 | -0.439 | 3.56e-12 |
| Respiratory electron transport | 103 | 1.23e-13 | -0.423 | 3.98e-12 |
| FCERI mediated MAPK activation | 65 | 1.89e-13 | -0.527 | 5.96e-12 |
| Cellular responses to stress | 666 | 2.46e-13 | -0.167 | 7.58e-12 |
| Cellular response to chemical stress | 151 | 7.82e-13 | -0.338 | 2.36e-11 |
| Metabolism of amino acids and derivatives | 330 | 1.43e-12 | -0.227 | 4.23e-11 |
| Protein localization | 157 | 2.07e-12 | -0.325 | 6.01e-11 |
Results (complete table)
Click HERE to show results for all gene sets
| set | setSize | pANOVA | s.dist | p.adjustANOVA |
|---|---|---|---|---|
| Metabolism | 1829 | 9.99e-42 | -0.192000 | 1.45e-38 |
| Innate Immune System | 939 | 3.77e-39 | -0.252000 | 2.74e-36 |
| Metabolism of proteins | 1695 | 7.22e-32 | -0.172000 | 3.49e-29 |
| Immune System | 1744 | 3.01e-30 | -0.165000 | 1.09e-27 |
| Disease | 1446 | 2.05e-29 | -0.177000 | 5.94e-27 |
| Classical antibody-mediated complement activation | 45 | 2.25e-27 | -0.933000 | 5.45e-25 |
| FCGR activation | 52 | 5.76e-26 | -0.844000 | 1.19e-23 |
| Initial triggering of complement | 57 | 8.45e-26 | -0.803000 | 1.53e-23 |
| Infectious disease | 761 | 4.75e-25 | -0.220000 | 7.66e-23 |
| Creation of C4 and C2 activators | 50 | 9.05e-25 | -0.839000 | 1.31e-22 |
| CD22 mediated BCR regulation | 43 | 1.18e-24 | -0.902000 | 1.55e-22 |
| Neutrophil degranulation | 441 | 4.05e-24 | -0.281000 | 4.90e-22 |
| Regulation of Complement cascade | 74 | 1.25e-23 | -0.673000 | 1.40e-21 |
| Translation | 294 | 6.15e-23 | -0.334000 | 6.37e-21 |
| Complement cascade | 81 | 1.71e-22 | -0.627000 | 1.66e-20 |
| Role of LAT2/NTAL/LAB on calcium mobilization | 49 | 3.31e-22 | -0.799000 | 3.00e-20 |
| Scavenging of heme from plasma | 46 | 6.14e-22 | -0.820000 | 5.24e-20 |
| FCGR3A-mediated phagocytosis | 99 | 2.73e-21 | -0.550000 | 1.98e-19 |
| Leishmania phagocytosis | 99 | 2.73e-21 | -0.550000 | 1.98e-19 |
| Parasite infection | 99 | 2.73e-21 | -0.550000 | 1.98e-19 |
| Regulation of actin dynamics for phagocytic cup formation | 101 | 6.07e-21 | -0.540000 | 4.19e-19 |
| Role of phospholipids in phagocytosis | 64 | 6.61e-20 | -0.660000 | 4.36e-18 |
| Fcgamma receptor (FCGR) dependent phagocytosis | 125 | 7.65e-20 | -0.472000 | 4.83e-18 |
| Adaptive Immune System | 718 | 1.88e-19 | -0.198000 | 1.14e-17 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | 68 | 2.89e-19 | -0.629000 | 1.68e-17 |
| Asparagine N-linked glycosylation | 274 | 5.99e-19 | -0.312000 | 3.22e-17 |
| Vesicle-mediated transport | 644 | 5.99e-19 | -0.206000 | 3.22e-17 |
| FCERI mediated NF-kB activation | 112 | 1.61e-18 | -0.480000 | 8.32e-17 |
| The citric acid (TCA) cycle and respiratory electron transport | 172 | 1.95e-18 | -0.387000 | 9.76e-17 |
| Signaling by the B Cell Receptor (BCR) | 146 | 3.89e-18 | -0.416000 | 1.88e-16 |
| Binding and Uptake of Ligands by Scavenger Receptors | 74 | 1.62e-17 | -0.572000 | 7.59e-16 |
| Post-translational protein modification | 1230 | 2.98e-17 | -0.144000 | 1.35e-15 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | 140 | 3.89e-17 | -0.412000 | 1.71e-15 |
| Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | 125 | 8.30e-17 | -0.431000 | 3.54e-15 |
| FCGR3A-mediated IL10 synthesis | 77 | 1.36e-16 | -0.545000 | 5.63e-15 |
| Metabolism of carbohydrates | 265 | 4.56e-16 | -0.290000 | 1.84e-14 |
| Mitochondrial translation elongation | 90 | 1.66e-15 | -0.485000 | 6.51e-14 |
| Mitochondrial translation initiation | 90 | 1.46e-14 | -0.469000 | 5.59e-13 |
| Fc epsilon receptor (FCERI) signaling | 165 | 1.66e-14 | -0.346000 | 6.19e-13 |
| FCERI mediated Ca+2 mobilization | 64 | 2.01e-14 | -0.553000 | 7.29e-13 |
| Cellular responses to stimuli | 676 | 3.22e-14 | -0.171000 | 1.14e-12 |
| Mitochondrial translation termination | 90 | 7.49e-14 | -0.456000 | 2.59e-12 |
| Diseases of metabolism | 209 | 9.33e-14 | -0.299000 | 3.15e-12 |
| Mitochondrial translation | 96 | 1.08e-13 | -0.439000 | 3.56e-12 |
| Respiratory electron transport | 103 | 1.23e-13 | -0.423000 | 3.98e-12 |
| FCERI mediated MAPK activation | 65 | 1.89e-13 | -0.527000 | 5.96e-12 |
| Cellular responses to stress | 666 | 2.46e-13 | -0.167000 | 7.58e-12 |
| Cellular response to chemical stress | 151 | 7.82e-13 | -0.338000 | 2.36e-11 |
| Metabolism of amino acids and derivatives | 330 | 1.43e-12 | -0.227000 | 4.23e-11 |
| Protein localization | 157 | 2.07e-12 | -0.325000 | 6.01e-11 |
| Cell surface interactions at the vascular wall | 148 | 5.46e-12 | -0.328000 | 1.55e-10 |
| Leishmania infection | 227 | 6.99e-12 | -0.264000 | 1.95e-10 |
| Metabolism of RNA | 681 | 7.34e-12 | -0.154000 | 2.01e-10 |
| HIV Infection | 225 | 2.96e-11 | -0.257000 | 7.96e-10 |
| Host Interactions of HIV factors | 128 | 6.68e-11 | -0.334000 | 1.76e-09 |
| Membrane Trafficking | 573 | 8.56e-11 | -0.159000 | 2.22e-09 |
| ER to Golgi Anterograde Transport | 132 | 9.71e-11 | -0.326000 | 2.47e-09 |
| Anti-inflammatory response favouring Leishmania parasite infection | 146 | 2.14e-10 | -0.304000 | 5.26e-09 |
| Leishmania parasite growth and survival | 146 | 2.14e-10 | -0.304000 | 5.26e-09 |
| COPI-mediated anterograde transport | 81 | 3.38e-10 | -0.404000 | 8.17e-09 |
| Transport to the Golgi and subsequent modification | 158 | 4.88e-10 | -0.287000 | 1.16e-08 |
| Disorders of transmembrane transporters | 143 | 7.89e-10 | -0.298000 | 1.85e-08 |
| Diseases of glycosylation | 129 | 2.21e-09 | -0.305000 | 5.08e-08 |
| SRP-dependent cotranslational protein targeting to membrane | 111 | 6.02e-09 | -0.320000 | 1.36e-07 |
| Transport of small molecules | 565 | 7.25e-09 | -0.143000 | 1.62e-07 |
| Cytoprotection by HMOX1 | 119 | 8.64e-09 | -0.305000 | 1.90e-07 |
| Complex I biogenesis | 57 | 1.07e-08 | -0.438000 | 2.32e-07 |
| Mitochondrial protein import | 64 | 1.79e-08 | -0.407000 | 3.81e-07 |
| Antigen processing-Cross presentation | 100 | 2.74e-08 | -0.322000 | 5.77e-07 |
| Influenza Viral RNA Transcription and Replication | 135 | 3.18e-08 | -0.276000 | 6.60e-07 |
| XBP1(S) activates chaperone genes | 47 | 3.90e-08 | -0.463000 | 7.97e-07 |
| PCP/CE pathway | 88 | 4.15e-08 | -0.338000 | 8.37e-07 |
| ABC transporter disorders | 69 | 5.53e-08 | -0.378000 | 1.09e-06 |
| IRE1alpha activates chaperones | 49 | 5.58e-08 | -0.448000 | 1.09e-06 |
| Regulation of expression of SLITs and ROBOs | 164 | 9.03e-08 | -0.242000 | 1.75e-06 |
| Defective CFTR causes cystic fibrosis | 58 | 9.21e-08 | -0.405000 | 1.76e-06 |
| rRNA processing in the nucleus and cytosol | 190 | 1.50e-07 | -0.221000 | 2.84e-06 |
| Influenza Infection | 154 | 2.06e-07 | -0.243000 | 3.84e-06 |
| rRNA processing | 214 | 3.20e-07 | -0.203000 | 5.87e-06 |
| Metabolism of lipids | 630 | 3.26e-07 | -0.119000 | 5.91e-06 |
| Signaling by ROBO receptors | 205 | 3.45e-07 | -0.207000 | 6.18e-06 |
| Glucose metabolism | 85 | 4.39e-07 | -0.317000 | 7.76e-06 |
| Major pathway of rRNA processing in the nucleolus and cytosol | 180 | 8.66e-07 | -0.213000 | 1.51e-05 |
| Cristae formation | 31 | 9.81e-07 | -0.508000 | 1.70e-05 |
| Hh mutants are degraded by ERAD | 53 | 1.09e-06 | -0.387000 | 1.86e-05 |
| Gluconeogenesis | 29 | 1.13e-06 | -0.522000 | 1.91e-05 |
| Cellular response to starvation | 151 | 1.31e-06 | -0.228000 | 2.19e-05 |
| UCH proteinases | 86 | 1.37e-06 | -0.301000 | 2.26e-05 |
| ER-Phagosome pathway | 85 | 1.55e-06 | -0.301000 | 2.53e-05 |
| Vpu mediated degradation of CD4 | 50 | 1.62e-06 | -0.392000 | 2.61e-05 |
| Eukaryotic Translation Elongation | 93 | 2.02e-06 | -0.285000 | 3.22e-05 |
| Eukaryotic Translation Termination | 92 | 2.04e-06 | -0.287000 | 3.22e-05 |
| The role of Nef in HIV-1 replication and disease pathogenesis | 27 | 2.10e-06 | -0.527000 | 3.27e-05 |
| Selenoamino acid metabolism | 115 | 2.23e-06 | -0.255000 | 3.44e-05 |
| MHC class II antigen presentation | 100 | 2.54e-06 | -0.272000 | 3.88e-05 |
| Cross-presentation of soluble exogenous antigens (endosomes) | 47 | 2.79e-06 | -0.395000 | 4.22e-05 |
| GLI3 is processed to GLI3R by the proteasome | 57 | 2.88e-06 | -0.358000 | 4.31e-05 |
| Lysosome Vesicle Biogenesis | 33 | 3.03e-06 | -0.470000 | 4.49e-05 |
| SCF-beta-TrCP mediated degradation of Emi1 | 53 | 3.50e-06 | -0.368000 | 5.13e-05 |
| Degradation of GLI2 by the proteasome | 57 | 3.94e-06 | -0.353000 | 5.71e-05 |
| Glycosaminoglycan metabolism | 112 | 4.01e-06 | -0.252000 | 5.76e-05 |
| ROS sensing by NFE2L2 | 55 | 4.52e-06 | -0.357000 | 6.42e-05 |
| Vif-mediated degradation of APOBEC3G | 52 | 4.68e-06 | -0.367000 | 6.60e-05 |
| Hh mutants abrogate ligand secretion | 55 | 4.82e-06 | -0.356000 | 6.73e-05 |
| Autodegradation of the E3 ubiquitin ligase COP1 | 49 | 6.22e-06 | -0.373000 | 8.59e-05 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | 94 | 6.28e-06 | -0.270000 | 8.60e-05 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | 53 | 6.93e-06 | -0.357000 | 9.40e-05 |
| Downstream TCR signaling | 94 | 7.87e-06 | -0.267000 | 1.06e-04 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | 20 | 8.06e-06 | -0.576000 | 1.07e-04 |
| Peptide chain elongation | 88 | 8.46e-06 | -0.275000 | 1.12e-04 |
| Regulation of RUNX3 expression and activity | 55 | 8.79e-06 | -0.346000 | 1.15e-04 |
| Ubiquitin-dependent degradation of Cyclin D | 50 | 9.00e-06 | -0.363000 | 1.17e-04 |
| Degradation of GLI1 by the proteasome | 57 | 9.42e-06 | -0.339000 | 1.21e-04 |
| Unfolded Protein Response (UPR) | 90 | 9.52e-06 | -0.270000 | 1.21e-04 |
| Hedgehog ligand biogenesis | 60 | 1.01e-05 | -0.330000 | 1.27e-04 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | 74 | 1.02e-05 | -0.297000 | 1.27e-04 |
| Degradation of DVL | 55 | 1.09e-05 | -0.343000 | 1.35e-04 |
| TCR signaling | 115 | 1.15e-05 | -0.237000 | 1.41e-04 |
| Hemostasis | 533 | 1.16e-05 | -0.111000 | 1.41e-04 |
| Viral mRNA Translation | 88 | 1.21e-05 | -0.270000 | 1.46e-04 |
| Diseases of carbohydrate metabolism | 29 | 1.27e-05 | -0.468000 | 1.53e-04 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | 48 | 1.32e-05 | -0.364000 | 1.57e-04 |
| Formation of a pool of free 40S subunits | 100 | 1.48e-05 | -0.251000 | 1.74e-04 |
| Plasma lipoprotein assembly, remodeling, and clearance | 56 | 1.54e-05 | -0.334000 | 1.80e-04 |
| Dectin-1 mediated noncanonical NF-kB signaling | 58 | 1.58e-05 | -0.328000 | 1.83e-04 |
| Negative regulation of NOTCH4 signaling | 54 | 1.67e-05 | -0.339000 | 1.89e-04 |
| Ubiquitin Mediated Degradation of Phosphorylated Cdc25A | 50 | 1.68e-05 | -0.352000 | 1.89e-04 |
| p53-Independent DNA Damage Response | 50 | 1.68e-05 | -0.352000 | 1.89e-04 |
| p53-Independent G1/S DNA damage checkpoint | 50 | 1.68e-05 | -0.352000 | 1.89e-04 |
| Cap-dependent Translation Initiation | 118 | 1.71e-05 | -0.229000 | 1.89e-04 |
| Eukaryotic Translation Initiation | 118 | 1.71e-05 | -0.229000 | 1.89e-04 |
| Formation of ATP by chemiosmotic coupling | 18 | 1.79e-05 | -0.584000 | 1.97e-04 |
| Selenocysteine synthesis | 92 | 2.13e-05 | -0.256000 | 2.32e-04 |
| Asymmetric localization of PCP proteins | 62 | 2.14e-05 | -0.312000 | 2.32e-04 |
| NIK–>noncanonical NF-kB signaling | 57 | 2.18e-05 | -0.325000 | 2.35e-04 |
| Regulation of Apoptosis | 51 | 2.23e-05 | -0.343000 | 2.38e-04 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | 53 | 2.33e-05 | -0.336000 | 2.46e-04 |
| trans-Golgi Network Vesicle Budding | 70 | 2.34e-05 | -0.292000 | 2.46e-04 |
| Regulation of HMOX1 expression and activity | 63 | 2.69e-05 | -0.306000 | 2.81e-04 |
| TNFR2 non-canonical NF-kB pathway | 94 | 2.90e-05 | -0.250000 | 3.00e-04 |
| Plasma lipoprotein clearance | 30 | 3.13e-05 | -0.439000 | 3.22e-04 |
| Detoxification of Reactive Oxygen Species | 33 | 3.27e-05 | -0.418000 | 3.34e-04 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | 58 | 3.42e-05 | -0.315000 | 3.47e-04 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | 111 | 3.52e-05 | -0.227000 | 3.55e-04 |
| Stabilization of p53 | 54 | 3.70e-05 | -0.325000 | 3.71e-04 |
| Diseases associated with glycosylation precursor biosynthesis | 18 | 4.34e-05 | -0.557000 | 4.32e-04 |
| Glycolysis | 67 | 4.75e-05 | -0.287000 | 4.69e-04 |
| Heparan sulfate/heparin (HS-GAG) metabolism | 45 | 4.96e-05 | -0.350000 | 4.86e-04 |
| Regulation of ornithine decarboxylase (ODC) | 49 | 5.56e-05 | -0.333000 | 5.41e-04 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | 177 | 5.82e-05 | -0.175000 | 5.63e-04 |
| L13a-mediated translational silencing of Ceruloplasmin expression | 110 | 6.08e-05 | -0.221000 | 5.81e-04 |
| Post-translational protein phosphorylation | 80 | 6.09e-05 | -0.259000 | 5.81e-04 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | 114 | 6.70e-05 | -0.216000 | 6.31e-04 |
| Nonsense-Mediated Decay (NMD) | 114 | 6.70e-05 | -0.216000 | 6.31e-04 |
| Diseases associated with glycosaminoglycan metabolism | 38 | 7.18e-05 | -0.372000 | 6.72e-04 |
| Autodegradation of Cdh1 by Cdh1:APC/C | 64 | 8.14e-05 | -0.285000 | 7.54e-04 |
| mRNA Splicing - Minor Pathway | 52 | 8.16e-05 | -0.316000 | 7.54e-04 |
| Activation of NF-kappaB in B cells | 65 | 8.34e-05 | -0.282000 | 7.66e-04 |
| Class I MHC mediated antigen processing & presentation | 358 | 8.50e-05 | -0.121000 | 7.76e-04 |
| Synthesis of substrates in N-glycan biosythesis | 59 | 8.71e-05 | -0.295000 | 7.90e-04 |
| Degradation of AXIN | 53 | 9.32e-05 | -0.310000 | 8.40e-04 |
| Autophagy | 128 | 9.40e-05 | -0.200000 | 8.42e-04 |
| Costimulation by the CD28 family | 66 | 1.08e-04 | -0.276000 | 9.56e-04 |
| APC/C:Cdc20 mediated degradation of Securin | 66 | 1.08e-04 | -0.276000 | 9.56e-04 |
| Processing of Capped Intron-Containing Pre-mRNA | 238 | 1.29e-04 | -0.144000 | 1.14e-03 |
| Macroautophagy | 113 | 1.31e-04 | -0.208000 | 1.15e-03 |
| GPVI-mediated activation cascade | 30 | 1.33e-04 | -0.403000 | 1.15e-03 |
| Metabolism of polyamines | 57 | 1.38e-04 | -0.292000 | 1.20e-03 |
| Iron uptake and transport | 56 | 1.44e-04 | -0.294000 | 1.23e-03 |
| SCF(Skp2)-mediated degradation of p27/p21 | 59 | 1.47e-04 | -0.286000 | 1.25e-03 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | 72 | 1.50e-04 | -0.258000 | 1.27e-03 |
| ABC-family proteins mediated transport | 95 | 1.51e-04 | -0.225000 | 1.28e-03 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | 100 | 1.55e-04 | -0.219000 | 1.30e-03 |
| Nucleotide Excision Repair | 110 | 1.64e-04 | -0.208000 | 1.36e-03 |
| Axon guidance | 490 | 1.64e-04 | -0.099600 | 1.36e-03 |
| Olfactory Signaling Pathway | 13 | 1.77e-04 | 0.600000 | 1.46e-03 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | 35 | 1.83e-04 | -0.365000 | 1.50e-03 |
| C-type lectin receptors (CLRs) | 123 | 2.16e-04 | -0.193000 | 1.76e-03 |
| Regulation of APC/C activators between G1/S and early anaphase | 78 | 2.21e-04 | -0.242000 | 1.79e-03 |
| NGF-stimulated transcription | 35 | 2.35e-04 | 0.359000 | 1.89e-03 |
| Mitochondrial biogenesis | 92 | 2.38e-04 | -0.222000 | 1.90e-03 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | 23 | 2.39e-04 | -0.443000 | 1.90e-03 |
| Phosphorylation of CD3 and TCR zeta chains | 22 | 2.54e-04 | -0.451000 | 2.01e-03 |
| HIV Life Cycle | 146 | 2.65e-04 | -0.175000 | 2.09e-03 |
| Elastic fibre formation | 38 | 3.09e-04 | -0.338000 | 2.43e-03 |
| PD-1 signaling | 23 | 3.22e-04 | -0.433000 | 2.51e-03 |
| Transcriptional regulation of pluripotent stem cells | 21 | 3.40e-04 | 0.452000 | 2.64e-03 |
| COPII-mediated vesicle transport | 66 | 3.43e-04 | -0.255000 | 2.64e-03 |
| Glycosphingolipid metabolism | 37 | 3.56e-04 | -0.339000 | 2.73e-03 |
| CDK-mediated phosphorylation and removal of Cdc6 | 70 | 3.60e-04 | -0.247000 | 2.75e-03 |
| Translocation of ZAP-70 to Immunological synapse | 19 | 4.14e-04 | -0.468000 | 3.13e-03 |
| ROS and RNS production in phagocytes | 33 | 4.15e-04 | -0.355000 | 3.13e-03 |
| Mucopolysaccharidoses | 11 | 4.34e-04 | -0.613000 | 3.26e-03 |
| Pyruvate metabolism and Citric Acid (TCA) cycle | 51 | 4.36e-04 | -0.285000 | 3.26e-03 |
| G1/S DNA Damage Checkpoints | 64 | 5.16e-04 | -0.251000 | 3.84e-03 |
| Nitric oxide stimulates guanylate cyclase | 20 | 5.32e-04 | 0.447000 | 3.94e-03 |
| p53-Dependent G1 DNA Damage Response | 62 | 5.38e-04 | -0.254000 | 3.94e-03 |
| p53-Dependent G1/S DNA damage checkpoint | 62 | 5.38e-04 | -0.254000 | 3.94e-03 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | 70 | 5.48e-04 | -0.239000 | 4.00e-03 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | 74 | 5.79e-04 | -0.231000 | 4.19e-03 |
| DNA Damage Recognition in GG-NER | 38 | 5.80e-04 | -0.323000 | 4.19e-03 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | 92 | 5.93e-04 | -0.207000 | 4.26e-03 |
| Downstream signaling events of B Cell Receptor (BCR) | 79 | 6.03e-04 | -0.223000 | 4.31e-03 |
| Phase 0 - rapid depolarisation | 26 | 6.12e-04 | 0.388000 | 4.36e-03 |
| Regulation of PTEN stability and activity | 67 | 6.46e-04 | -0.241000 | 4.57e-03 |
| Cyclin A:Cdk2-associated events at S phase entry | 84 | 6.72e-04 | -0.215000 | 4.73e-03 |
| LDL clearance | 18 | 6.74e-04 | -0.463000 | 4.73e-03 |
| Chondroitin sulfate/dermatan sulfate metabolism | 46 | 7.23e-04 | -0.288000 | 5.03e-03 |
| Orc1 removal from chromatin | 68 | 7.25e-04 | -0.237000 | 5.03e-03 |
| mRNA Splicing | 187 | 7.28e-04 | -0.143000 | 5.03e-03 |
| Viral Messenger RNA Synthesis | 44 | 7.42e-04 | -0.294000 | 5.10e-03 |
| Hedgehog ‘on’ state | 82 | 7.77e-04 | -0.215000 | 5.32e-03 |
| Synthesis of DNA | 117 | 8.11e-04 | -0.179000 | 5.52e-03 |
| Pausing and recovery of Tat-mediated HIV elongation | 30 | 8.71e-04 | -0.351000 | 5.88e-03 |
| Tat-mediated HIV elongation arrest and recovery | 30 | 8.71e-04 | -0.351000 | 5.88e-03 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | 73 | 8.96e-04 | -0.225000 | 6.02e-03 |
| Transferrin endocytosis and recycling | 29 | 9.22e-04 | -0.355000 | 6.16e-03 |
| Cyclin E associated events during G1/S transition | 82 | 9.65e-04 | -0.211000 | 6.40e-03 |
| mRNA Splicing - Major Pathway | 179 | 9.66e-04 | -0.143000 | 6.40e-03 |
| Neddylation | 224 | 9.84e-04 | -0.128000 | 6.49e-03 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | 22 | 1.01e-03 | -0.405000 | 6.66e-03 |
| SLC transporter disorders | 74 | 1.04e-03 | -0.221000 | 6.77e-03 |
| CLEC7A (Dectin-1) signaling | 96 | 1.05e-03 | -0.194000 | 6.80e-03 |
| Regulation of RAS by GAPs | 65 | 1.08e-03 | -0.234000 | 7.00e-03 |
| Late Phase of HIV Life Cycle | 133 | 1.09e-03 | -0.164000 | 7.01e-03 |
| Platelet activation, signaling and aggregation | 229 | 1.12e-03 | -0.125000 | 7.17e-03 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | 71 | 1.14e-03 | -0.223000 | 7.27e-03 |
| TP53 Regulates Metabolic Genes | 85 | 1.14e-03 | -0.204000 | 7.27e-03 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | 28 | 1.16e-03 | -0.355000 | 7.34e-03 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | 87 | 1.18e-03 | -0.201000 | 7.47e-03 |
| cGMP effects | 15 | 1.26e-03 | 0.481000 | 7.87e-03 |
| Nervous system development | 511 | 1.26e-03 | -0.083500 | 7.87e-03 |
| Keratan sulfate degradation | 12 | 1.28e-03 | -0.537000 | 7.96e-03 |
| HIV elongation arrest and recovery | 32 | 1.30e-03 | -0.329000 | 8.00e-03 |
| Pausing and recovery of HIV elongation | 32 | 1.30e-03 | -0.329000 | 8.00e-03 |
| Cargo recognition for clathrin-mediated endocytosis | 95 | 1.36e-03 | -0.190000 | 8.36e-03 |
| SLC-mediated transmembrane transport | 172 | 1.43e-03 | -0.141000 | 8.74e-03 |
| VLDLR internalisation and degradation | 11 | 1.48e-03 | -0.554000 | 9.00e-03 |
| Degradation of beta-catenin by the destruction complex | 83 | 1.59e-03 | -0.201000 | 9.62e-03 |
| Citric acid cycle (TCA cycle) | 22 | 1.64e-03 | -0.388000 | 9.90e-03 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | 27 | 1.65e-03 | -0.350000 | 9.92e-03 |
| Golgi-to-ER retrograde transport | 109 | 1.67e-03 | -0.174000 | 1.00e-02 |
| WNT5A-dependent internalization of FZD4 | 14 | 1.73e-03 | -0.484000 | 1.03e-02 |
| Assembly of the pre-replicative complex | 79 | 1.74e-03 | -0.204000 | 1.04e-02 |
| HCMV Infection | 91 | 1.82e-03 | -0.189000 | 1.08e-02 |
| CDT1 association with the CDC6:ORC:origin complex | 57 | 1.89e-03 | -0.238000 | 1.11e-02 |
| Golgi Associated Vesicle Biogenesis | 55 | 1.90e-03 | -0.242000 | 1.11e-02 |
| Global Genome Nucleotide Excision Repair (GG-NER) | 84 | 1.90e-03 | -0.196000 | 1.11e-02 |
| DNA Replication Pre-Initiation | 94 | 2.03e-03 | -0.184000 | 1.18e-02 |
| Nuclear Events (kinase and transcription factor activation) | 57 | 2.05e-03 | 0.236000 | 1.19e-02 |
| Cellular response to hypoxia | 72 | 2.13e-03 | -0.209000 | 1.23e-02 |
| HCMV Late Events | 63 | 2.13e-03 | -0.224000 | 1.23e-02 |
| Switching of origins to a post-replicative state | 88 | 2.15e-03 | -0.189000 | 1.23e-02 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | 13 | 2.26e-03 | -0.489000 | 1.29e-02 |
| APC/C-mediated degradation of cell cycle proteins | 85 | 2.34e-03 | -0.191000 | 1.33e-02 |
| Regulation of mitotic cell cycle | 85 | 2.34e-03 | -0.191000 | 1.33e-02 |
| Molecules associated with elastic fibres | 28 | 2.35e-03 | -0.332000 | 1.33e-02 |
| Antimicrobial peptides | 33 | 2.39e-03 | -0.305000 | 1.35e-02 |
| Amyloid fiber formation | 45 | 2.41e-03 | -0.261000 | 1.35e-02 |
| RHO GTPases Activate NADPH Oxidases | 21 | 2.47e-03 | -0.382000 | 1.38e-02 |
| Telomere Maintenance | 73 | 2.56e-03 | -0.204000 | 1.42e-02 |
| Amino acids regulate mTORC1 | 51 | 2.59e-03 | -0.244000 | 1.43e-02 |
| Fatty acid metabolism | 149 | 2.66e-03 | -0.143000 | 1.47e-02 |
| Infection with Mycobacterium tuberculosis | 27 | 2.72e-03 | -0.333000 | 1.49e-02 |
| Metabolism of non-coding RNA | 53 | 2.73e-03 | -0.238000 | 1.49e-02 |
| snRNP Assembly | 53 | 2.73e-03 | -0.238000 | 1.49e-02 |
| NOTCH3 Intracellular Domain Regulates Transcription | 22 | 2.88e-03 | 0.367000 | 1.57e-02 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | 64 | 2.97e-03 | -0.215000 | 1.61e-02 |
| Signaling by Hedgehog | 130 | 3.10e-03 | -0.150000 | 1.67e-02 |
| tRNA processing in the nucleus | 59 | 3.13e-03 | -0.222000 | 1.68e-02 |
| TP53 Regulates Transcription of Death Receptors and Ligands | 12 | 3.39e-03 | 0.489000 | 1.81e-02 |
| DNA Repair | 284 | 3.43e-03 | -0.101000 | 1.83e-02 |
| Calnexin/calreticulin cycle | 26 | 3.46e-03 | -0.331000 | 1.84e-02 |
| Regulation of RUNX2 expression and activity | 71 | 3.70e-03 | -0.199000 | 1.96e-02 |
| Ca2+ pathway | 56 | 3.75e-03 | 0.224000 | 1.98e-02 |
| CS/DS degradation | 11 | 3.77e-03 | -0.504000 | 1.98e-02 |
| TBC/RABGAPs | 44 | 3.93e-03 | -0.251000 | 2.06e-02 |
| DNA Replication | 136 | 4.04e-03 | -0.143000 | 2.11e-02 |
| CD28 co-stimulation | 32 | 4.08e-03 | -0.293000 | 2.12e-02 |
| Diseases associated with N-glycosylation of proteins | 17 | 4.25e-03 | -0.401000 | 2.20e-02 |
| Mitophagy | 28 | 4.33e-03 | -0.312000 | 2.23e-02 |
| Transcriptional regulation by small RNAs | 57 | 4.33e-03 | -0.218000 | 2.23e-02 |
| Sphingolipid metabolism | 77 | 4.37e-03 | -0.188000 | 2.24e-02 |
| Response to elevated platelet cytosolic Ca2+ | 116 | 4.44e-03 | -0.153000 | 2.27e-02 |
| tRNA Aminoacylation | 42 | 4.49e-03 | -0.253000 | 2.28e-02 |
| Laminin interactions | 23 | 4.50e-03 | 0.342000 | 2.28e-02 |
| Plasma lipoprotein assembly | 12 | 4.61e-03 | -0.472000 | 2.33e-02 |
| Rab regulation of trafficking | 120 | 4.86e-03 | -0.149000 | 2.45e-02 |
| HS-GAG degradation | 21 | 4.98e-03 | -0.354000 | 2.50e-02 |
| Nucleotide biosynthesis | 12 | 5.06e-03 | -0.467000 | 2.53e-02 |
| Peroxisomal protein import | 57 | 5.13e-03 | -0.214000 | 2.56e-02 |
| COPI-dependent Golgi-to-ER retrograde traffic | 76 | 5.20e-03 | -0.185000 | 2.58e-02 |
| Signaling by FGFR2 IIIa TM | 19 | 5.38e-03 | -0.369000 | 2.67e-02 |
| Platelet degranulation | 112 | 5.42e-03 | -0.152000 | 2.67e-02 |
| Beta-catenin independent WNT signaling | 136 | 5.43e-03 | -0.138000 | 2.67e-02 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | 78 | 5.47e-03 | -0.182000 | 2.68e-02 |
| NOTCH4 Intracellular Domain Regulates Transcription | 19 | 6.09e-03 | 0.363000 | 2.97e-02 |
| rRNA modification in the nucleus and cytosol | 59 | 6.12e-03 | -0.206000 | 2.98e-02 |
| Clathrin-mediated endocytosis | 132 | 6.44e-03 | -0.137000 | 3.13e-02 |
| CD28 dependent Vav1 pathway | 11 | 6.68e-03 | -0.472000 | 3.23e-02 |
| Interferon alpha/beta signaling | 56 | 6.76e-03 | 0.209000 | 3.25e-02 |
| Biological oxidations | 151 | 6.78e-03 | -0.128000 | 3.25e-02 |
| Signaling by Interleukins | 393 | 6.78e-03 | -0.079700 | 3.25e-02 |
| Interleukin-1 signaling | 99 | 6.92e-03 | -0.157000 | 3.30e-02 |
| Hedgehog ‘off’ state | 96 | 7.01e-03 | -0.159000 | 3.33e-02 |
| Signaling by NOTCH4 | 81 | 7.02e-03 | -0.173000 | 3.33e-02 |
| Response of Mtb to phagocytosis | 23 | 7.56e-03 | -0.322000 | 3.57e-02 |
| Formation of the ternary complex, and subsequently, the 43S complex | 51 | 7.79e-03 | -0.215000 | 3.67e-02 |
| Mitotic G1 phase and G1/S transition | 146 | 7.93e-03 | -0.127000 | 3.72e-02 |
| Ribosomal scanning and start codon recognition | 58 | 8.29e-03 | -0.200000 | 3.88e-02 |
| SARS-CoV-2 Infection | 69 | 8.32e-03 | -0.184000 | 3.88e-02 |
| Extracellular matrix organization | 263 | 8.50e-03 | -0.094300 | 3.95e-02 |
| Mitochondrial Fatty Acid Beta-Oxidation | 35 | 8.53e-03 | -0.257000 | 3.95e-02 |
| RHO GTPases Activate WASPs and WAVEs | 36 | 8.55e-03 | -0.253000 | 3.95e-02 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | 76 | 8.79e-03 | -0.174000 | 4.05e-02 |
| Late endosomal microautophagy | 31 | 8.90e-03 | -0.271000 | 4.09e-02 |
| Striated Muscle Contraction | 31 | 9.08e-03 | -0.271000 | 4.16e-02 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | 59 | 9.43e-03 | -0.195000 | 4.30e-02 |
| Response to metal ions | 10 | 9.80e-03 | -0.472000 | 4.46e-02 |
| Resolution of Sister Chromatid Cohesion | 103 | 9.91e-03 | 0.147000 | 4.50e-02 |
| Recycling pathway of L1 | 27 | 1.01e-02 | -0.286000 | 4.54e-02 |
| tRNA processing | 130 | 1.02e-02 | -0.131000 | 4.56e-02 |
| RNA Polymerase III Transcription Initiation | 36 | 1.02e-02 | -0.248000 | 4.56e-02 |
| Hyaluronan metabolism | 17 | 1.02e-02 | -0.360000 | 4.56e-02 |
| G1/S Transition | 128 | 1.02e-02 | -0.131000 | 4.56e-02 |
| Antigen processing: Ubiquitination & Proteasome degradation | 294 | 1.04e-02 | -0.086900 | 4.65e-02 |
| Regulation of PTEN mRNA translation | 12 | 1.06e-02 | 0.426000 | 4.71e-02 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | 10 | 1.06e-02 | 0.466000 | 4.71e-02 |
| Organelle biogenesis and maintenance | 271 | 1.08e-02 | -0.090100 | 4.75e-02 |
| Deubiquitination | 234 | 1.08e-02 | -0.096800 | 4.76e-02 |
| Removal of the Flap Intermediate from the C-strand | 17 | 1.09e-02 | -0.357000 | 4.79e-02 |
| Selective autophagy | 59 | 1.11e-02 | -0.191000 | 4.87e-02 |
| Hyaluronan uptake and degradation | 12 | 1.12e-02 | -0.423000 | 4.88e-02 |
| Retrograde neurotrophin signalling | 14 | 1.13e-02 | -0.391000 | 4.88e-02 |
| HS-GAG biosynthesis | 25 | 1.13e-02 | -0.293000 | 4.88e-02 |
| Inhibition of DNA recombination at telomere | 30 | 1.13e-02 | -0.267000 | 4.89e-02 |
| Removal of the Flap Intermediate | 14 | 1.14e-02 | -0.390000 | 4.92e-02 |
| SARS-CoV Infections | 149 | 1.15e-02 | -0.120000 | 4.93e-02 |
| Generation of second messenger molecules | 33 | 1.17e-02 | -0.254000 | 5.00e-02 |
| S Phase | 159 | 1.19e-02 | -0.116000 | 5.07e-02 |
| Glycogen storage diseases | 14 | 1.23e-02 | -0.386000 | 5.25e-02 |
| Metal ion SLC transporters | 20 | 1.26e-02 | -0.322000 | 5.33e-02 |
| RNA Polymerase III Abortive And Retractive Initiation | 41 | 1.30e-02 | -0.224000 | 5.47e-02 |
| RNA Polymerase III Transcription | 41 | 1.30e-02 | -0.224000 | 5.47e-02 |
| Metabolism of nucleotides | 87 | 1.33e-02 | -0.154000 | 5.59e-02 |
| Translation initiation complex formation | 58 | 1.35e-02 | -0.188000 | 5.65e-02 |
| Metabolism of porphyrins | 21 | 1.38e-02 | -0.311000 | 5.76e-02 |
| Scavenging by Class A Receptors | 17 | 1.38e-02 | -0.345000 | 5.77e-02 |
| Base Excision Repair | 53 | 1.39e-02 | -0.195000 | 5.77e-02 |
| CD28 dependent PI3K/Akt signaling | 21 | 1.51e-02 | -0.306000 | 6.24e-02 |
| Formation of the Early Elongation Complex | 33 | 1.57e-02 | -0.243000 | 6.48e-02 |
| Formation of the HIV-1 Early Elongation Complex | 33 | 1.57e-02 | -0.243000 | 6.48e-02 |
| Signal regulatory protein family interactions | 11 | 1.58e-02 | -0.420000 | 6.50e-02 |
| Developmental Biology | 780 | 1.66e-02 | -0.050600 | 6.80e-02 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | 14 | 1.71e-02 | -0.368000 | 6.98e-02 |
| Defective Intrinsic Pathway for Apoptosis | 22 | 1.73e-02 | -0.293000 | 7.07e-02 |
| Interleukin-1 family signaling | 128 | 1.74e-02 | -0.122000 | 7.08e-02 |
| Cytosolic tRNA aminoacylation | 24 | 1.78e-02 | -0.279000 | 7.21e-02 |
| Resolution of Abasic Sites (AP sites) | 38 | 1.79e-02 | -0.222000 | 7.24e-02 |
| RNA Polymerase III Chain Elongation | 18 | 1.82e-02 | -0.321000 | 7.34e-02 |
| FOXO-mediated transcription of cell cycle genes | 15 | 1.84e-02 | 0.352000 | 7.39e-02 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | 13 | 1.89e-02 | 0.376000 | 7.56e-02 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | 64 | 1.89e-02 | -0.170000 | 7.56e-02 |
| A tetrasaccharide linker sequence is required for GAG synthesis | 23 | 1.91e-02 | -0.282000 | 7.62e-02 |
| Cholesterol biosynthesis | 24 | 1.93e-02 | -0.276000 | 7.69e-02 |
| Interactions of Vpr with host cellular proteins | 37 | 1.95e-02 | -0.222000 | 7.71e-02 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | 31 | 1.95e-02 | -0.242000 | 7.72e-02 |
| Transport of bile salts and organic acids, metal ions and amine compounds | 54 | 2.01e-02 | -0.183000 | 7.92e-02 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | 39 | 2.03e-02 | -0.215000 | 7.97e-02 |
| Signaling by WNT | 253 | 2.04e-02 | -0.084700 | 8.00e-02 |
| Defective B3GALT6 causes EDSP2 and SEMDJL1 | 17 | 2.05e-02 | -0.325000 | 8.00e-02 |
| Interaction between L1 and Ankyrins | 25 | 2.05e-02 | 0.268000 | 8.01e-02 |
| Dual incision in TC-NER | 65 | 2.10e-02 | -0.166000 | 8.16e-02 |
| Cardiac conduction | 98 | 2.17e-02 | 0.134000 | 8.39e-02 |
| Transcriptional regulation by RUNX2 | 115 | 2.17e-02 | -0.124000 | 8.39e-02 |
| Glycogen metabolism | 26 | 2.17e-02 | -0.260000 | 8.39e-02 |
| Defective B3GAT3 causes JDSSDHD | 17 | 2.19e-02 | -0.321000 | 8.41e-02 |
| Insulin receptor recycling | 23 | 2.20e-02 | -0.276000 | 8.46e-02 |
| Factors involved in megakaryocyte development and platelet production | 110 | 2.21e-02 | 0.126000 | 8.47e-02 |
| Gamma carboxylation, hypusine formation and arylsulfatase activation | 35 | 2.26e-02 | -0.223000 | 8.61e-02 |
| Signal transduction by L1 | 21 | 2.28e-02 | -0.287000 | 8.67e-02 |
| Cytokine Signaling in Immune system | 617 | 2.28e-02 | -0.053800 | 8.67e-02 |
| Signaling by Hippo | 20 | 2.30e-02 | 0.294000 | 8.71e-02 |
| PIWI-interacting RNA (piRNA) biogenesis | 22 | 2.40e-02 | -0.278000 | 9.04e-02 |
| Processive synthesis on the lagging strand | 15 | 2.40e-02 | -0.337000 | 9.04e-02 |
| Defective B4GALT7 causes EDS, progeroid type | 17 | 2.44e-02 | -0.315000 | 9.12e-02 |
| Gastrin-CREB signalling pathway via PKC and MAPK | 16 | 2.44e-02 | -0.325000 | 9.12e-02 |
| Budding and maturation of HIV virion | 28 | 2.45e-02 | -0.246000 | 9.12e-02 |
| Trafficking and processing of endosomal TLR | 13 | 2.46e-02 | -0.360000 | 9.12e-02 |
| Sensory processing of sound by inner hair cells of the cochlea | 52 | 2.46e-02 | -0.180000 | 9.12e-02 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | 42 | 2.47e-02 | -0.200000 | 9.12e-02 |
| HIV Transcription Elongation | 42 | 2.47e-02 | -0.200000 | 9.12e-02 |
| Tat-mediated elongation of the HIV-1 transcript | 42 | 2.47e-02 | -0.200000 | 9.12e-02 |
| E3 ubiquitin ligases ubiquitinate target proteins | 47 | 2.48e-02 | -0.189000 | 9.12e-02 |
| HCMV Early Events | 67 | 2.48e-02 | -0.159000 | 9.12e-02 |
| Cargo concentration in the ER | 31 | 2.49e-02 | -0.233000 | 9.13e-02 |
| Protein folding | 86 | 2.51e-02 | -0.140000 | 9.17e-02 |
| Interleukin-12 family signaling | 49 | 2.60e-02 | -0.184000 | 9.48e-02 |
| SUMOylation of DNA replication proteins | 46 | 2.63e-02 | -0.189000 | 9.58e-02 |
| RUNX3 regulates NOTCH signaling | 14 | 2.65e-02 | 0.342000 | 9.63e-02 |
| Cell junction organization | 68 | 2.78e-02 | 0.154000 | 1.01e-01 |
| Transcriptional Regulation by MECP2 | 51 | 2.80e-02 | 0.178000 | 1.01e-01 |
| Pyruvate metabolism | 27 | 2.83e-02 | -0.244000 | 1.02e-01 |
| RNA Polymerase III Transcription Termination | 23 | 2.85e-02 | -0.264000 | 1.02e-01 |
| Formation of HIV elongation complex in the absence of HIV Tat | 44 | 2.86e-02 | -0.191000 | 1.03e-01 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | 90 | 2.90e-02 | 0.133000 | 1.04e-01 |
| Amplification of signal from the kinetochores | 90 | 2.90e-02 | 0.133000 | 1.04e-01 |
| Kinesins | 37 | 2.91e-02 | 0.207000 | 1.04e-01 |
| Apoptosis | 168 | 2.95e-02 | -0.097400 | 1.05e-01 |
| Golgi Cisternae Pericentriolar Stack Reorganization | 14 | 2.96e-02 | -0.336000 | 1.05e-01 |
| Protein ubiquitination | 67 | 2.97e-02 | -0.154000 | 1.05e-01 |
| Degradation of cysteine and homocysteine | 13 | 3.00e-02 | -0.348000 | 1.06e-01 |
| Metabolism of vitamins and cofactors | 163 | 3.04e-02 | -0.098300 | 1.07e-01 |
| Peptide ligand-binding receptors | 100 | 3.04e-02 | 0.125000 | 1.07e-01 |
| Activation of the AP-1 family of transcription factors | 10 | 3.07e-02 | 0.395000 | 1.07e-01 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | 24 | 3.07e-02 | 0.255000 | 1.07e-01 |
| Interleukin-2 family signaling | 36 | 3.09e-02 | -0.208000 | 1.07e-01 |
| Phase II - Conjugation of compounds | 74 | 3.12e-02 | -0.145000 | 1.08e-01 |
| Apoptotic execution phase | 46 | 3.13e-02 | 0.184000 | 1.08e-01 |
| Intracellular signaling by second messengers | 290 | 3.14e-02 | -0.073500 | 1.09e-01 |
| Vpr-mediated nuclear import of PICs | 34 | 3.18e-02 | -0.213000 | 1.09e-01 |
| Gene Silencing by RNA | 84 | 3.18e-02 | -0.136000 | 1.09e-01 |
| Processive synthesis on the C-strand of the telomere | 19 | 3.24e-02 | -0.284000 | 1.11e-01 |
| mTORC1-mediated signalling | 24 | 3.26e-02 | -0.252000 | 1.11e-01 |
| Intra-Golgi traffic | 43 | 3.36e-02 | -0.187000 | 1.15e-01 |
| Zinc transporters | 12 | 3.52e-02 | -0.351000 | 1.20e-01 |
| Formation of TC-NER Pre-Incision Complex | 53 | 3.62e-02 | -0.166000 | 1.23e-01 |
| Long-term potentiation | 19 | 3.66e-02 | 0.277000 | 1.24e-01 |
| Regulation of signaling by CBL | 18 | 3.69e-02 | -0.284000 | 1.25e-01 |
| G2/M Checkpoints | 132 | 3.74e-02 | -0.105000 | 1.26e-01 |
| Sulfur amino acid metabolism | 25 | 3.75e-02 | -0.240000 | 1.26e-01 |
| Class I peroxisomal membrane protein import | 20 | 3.75e-02 | -0.269000 | 1.26e-01 |
| Metabolism of fat-soluble vitamins | 34 | 3.78e-02 | -0.206000 | 1.26e-01 |
| Glutathione conjugation | 30 | 3.78e-02 | -0.219000 | 1.26e-01 |
| G-protein beta:gamma signalling | 28 | 3.78e-02 | -0.227000 | 1.26e-01 |
| Mitochondrial iron-sulfur cluster biogenesis | 13 | 3.79e-02 | -0.333000 | 1.26e-01 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | 13 | 3.83e-02 | 0.332000 | 1.27e-01 |
| PIP3 activates AKT signaling | 252 | 3.90e-02 | -0.075600 | 1.29e-01 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | 12 | 3.96e-02 | 0.343000 | 1.31e-01 |
| Mitochondrial tRNA aminoacylation | 21 | 3.97e-02 | -0.259000 | 1.31e-01 |
| Chaperonin-mediated protein folding | 80 | 3.99e-02 | -0.133000 | 1.31e-01 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | 25 | 4.00e-02 | -0.237000 | 1.31e-01 |
| Transport of Mature mRNA Derived from an Intronless Transcript | 42 | 4.00e-02 | -0.183000 | 1.31e-01 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | 25 | 4.02e-02 | -0.237000 | 1.31e-01 |
| EML4 and NUDC in mitotic spindle formation | 94 | 4.04e-02 | 0.122000 | 1.32e-01 |
| Metabolic disorders of biological oxidation enzymes | 25 | 4.05e-02 | -0.237000 | 1.32e-01 |
| DAP12 interactions | 38 | 4.06e-02 | -0.192000 | 1.32e-01 |
| Sensory processing of sound | 57 | 4.13e-02 | -0.156000 | 1.33e-01 |
| ER Quality Control Compartment (ERQC) | 21 | 4.15e-02 | -0.257000 | 1.33e-01 |
| EPH-ephrin mediated repulsion of cells | 45 | 4.16e-02 | -0.176000 | 1.33e-01 |
| Mitotic Prometaphase | 183 | 4.16e-02 | 0.087400 | 1.33e-01 |
| Diseases associated with the TLR signaling cascade | 27 | 4.17e-02 | -0.226000 | 1.33e-01 |
| Diseases of Immune System | 27 | 4.17e-02 | -0.226000 | 1.33e-01 |
| Early Phase of HIV Life Cycle | 14 | 4.18e-02 | -0.314000 | 1.33e-01 |
| Rev-mediated nuclear export of HIV RNA | 35 | 4.19e-02 | -0.199000 | 1.33e-01 |
| Metabolism of steroids | 124 | 4.19e-02 | -0.106000 | 1.33e-01 |
| Ub-specific processing proteases | 161 | 4.20e-02 | -0.092900 | 1.33e-01 |
| Glycerophospholipid biosynthesis | 107 | 4.26e-02 | -0.114000 | 1.35e-01 |
| MECP2 regulates neuronal receptors and channels | 15 | 4.39e-02 | 0.301000 | 1.39e-01 |
| MTOR signalling | 41 | 4.43e-02 | -0.182000 | 1.40e-01 |
| Interleukin-12 signaling | 41 | 4.50e-02 | -0.181000 | 1.41e-01 |
| The canonical retinoid cycle in rods (twilight vision) | 14 | 4.58e-02 | -0.308000 | 1.44e-01 |
| Transport of the SLBP independent Mature mRNA | 35 | 4.60e-02 | -0.195000 | 1.44e-01 |
| Recognition of DNA damage by PCNA-containing replication complex | 30 | 4.65e-02 | -0.210000 | 1.45e-01 |
| Nucleotide salvage | 22 | 4.67e-02 | -0.245000 | 1.46e-01 |
| Glutamate Neurotransmitter Release Cycle | 22 | 4.73e-02 | 0.244000 | 1.47e-01 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | 43 | 4.75e-02 | -0.175000 | 1.48e-01 |
| MAP2K and MAPK activation | 35 | 4.80e-02 | -0.193000 | 1.49e-01 |
| PINK1-PRKN Mediated Mitophagy | 21 | 4.83e-02 | -0.249000 | 1.49e-01 |
| Mitotic Prophase | 92 | 4.89e-02 | -0.119000 | 1.51e-01 |
| TCF dependent signaling in response to WNT | 168 | 4.95e-02 | -0.087900 | 1.53e-01 |
| Synthesis of PC | 24 | 4.98e-02 | -0.231000 | 1.53e-01 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | 14 | 5.00e-02 | -0.302000 | 1.53e-01 |
| FGFR2 mutant receptor activation | 26 | 5.01e-02 | -0.222000 | 1.53e-01 |
| Formation of RNA Pol II elongation complex | 57 | 5.06e-02 | -0.150000 | 1.54e-01 |
| RNA Polymerase II Transcription Elongation | 57 | 5.06e-02 | -0.150000 | 1.54e-01 |
| Nuclear Pore Complex (NPC) Disassembly | 36 | 5.08e-02 | -0.188000 | 1.55e-01 |
| Defensins | 10 | 5.11e-02 | -0.356000 | 1.55e-01 |
| Mitotic Spindle Checkpoint | 107 | 5.11e-02 | 0.109000 | 1.55e-01 |
| Tight junction interactions | 18 | 5.14e-02 | 0.265000 | 1.55e-01 |
| Signal Transduction | 2115 | 5.22e-02 | 0.025800 | 1.57e-01 |
| Regulation of TNFR1 signaling | 35 | 5.24e-02 | -0.189000 | 1.58e-01 |
| EGFR downregulation | 29 | 5.28e-02 | -0.208000 | 1.59e-01 |
| Nuclear signaling by ERBB4 | 30 | 5.33e-02 | -0.204000 | 1.60e-01 |
| Beta-oxidation of very long chain fatty acids | 10 | 5.37e-02 | -0.352000 | 1.60e-01 |
| Glutamate and glutamine metabolism | 12 | 5.38e-02 | -0.322000 | 1.60e-01 |
| Transport of the SLBP Dependant Mature mRNA | 36 | 5.54e-02 | -0.184000 | 1.65e-01 |
| PCNA-Dependent Long Patch Base Excision Repair | 21 | 5.57e-02 | -0.241000 | 1.66e-01 |
| Plasma lipoprotein remodeling | 22 | 5.59e-02 | -0.235000 | 1.66e-01 |
| alpha-linolenic (omega3) and linoleic (omega6) acid metabolism | 13 | 5.62e-02 | -0.306000 | 1.66e-01 |
| alpha-linolenic acid (ALA) metabolism | 13 | 5.62e-02 | -0.306000 | 1.66e-01 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | 17 | 5.64e-02 | -0.267000 | 1.66e-01 |
| SUMOylation of SUMOylation proteins | 35 | 5.64e-02 | -0.186000 | 1.66e-01 |
| Diseases associated with O-glycosylation of proteins | 57 | 5.73e-02 | -0.146000 | 1.68e-01 |
| Ras activation upon Ca2+ influx through NMDA receptor | 17 | 5.78e-02 | 0.266000 | 1.69e-01 |
| Apoptotic cleavage of cellular proteins | 36 | 5.79e-02 | 0.183000 | 1.69e-01 |
| SUMOylation of ubiquitinylation proteins | 39 | 5.87e-02 | -0.175000 | 1.71e-01 |
| Sema3A PAK dependent Axon repulsion | 16 | 5.90e-02 | -0.273000 | 1.72e-01 |
| Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane | 10 | 6.00e-02 | -0.343000 | 1.74e-01 |
| Class A/1 (Rhodopsin-like receptors) | 176 | 6.03e-02 | 0.082100 | 1.75e-01 |
| G alpha (q) signalling events | 147 | 6.19e-02 | 0.089200 | 1.79e-01 |
| Diseases of programmed cell death | 50 | 6.29e-02 | -0.152000 | 1.82e-01 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | 32 | 6.38e-02 | -0.189000 | 1.84e-01 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | 32 | 6.38e-02 | -0.189000 | 1.84e-01 |
| GRB2 events in EGFR signaling | 12 | 6.39e-02 | -0.309000 | 1.84e-01 |
| Extension of Telomeres | 49 | 6.42e-02 | -0.153000 | 1.84e-01 |
| RAF/MAP kinase cascade | 246 | 6.51e-02 | -0.068300 | 1.86e-01 |
| Smooth Muscle Contraction | 34 | 6.61e-02 | 0.182000 | 1.89e-01 |
| NOTCH1 Intracellular Domain Regulates Transcription | 47 | 6.66e-02 | 0.155000 | 1.90e-01 |
| Transport of Ribonucleoproteins into the Host Nucleus | 32 | 6.71e-02 | -0.187000 | 1.91e-01 |
| Signaling by high-kinase activity BRAF mutants | 31 | 6.73e-02 | -0.190000 | 1.91e-01 |
| Phospholipid metabolism | 186 | 6.74e-02 | -0.077800 | 1.91e-01 |
| MAPK6/MAPK4 signaling | 84 | 6.77e-02 | -0.115000 | 1.91e-01 |
| Defective EXT1 causes exostoses 1, TRPS2 and CHDS | 14 | 6.77e-02 | -0.282000 | 1.91e-01 |
| Defective EXT2 causes exostoses 2 | 14 | 6.77e-02 | -0.282000 | 1.91e-01 |
| Interleukin-6 signaling | 11 | 6.88e-02 | 0.317000 | 1.94e-01 |
| Transport of inorganic cations/anions and amino acids/oligopeptides | 75 | 6.90e-02 | -0.121000 | 1.94e-01 |
| Establishment of Sister Chromatid Cohesion | 11 | 6.92e-02 | 0.316000 | 1.94e-01 |
| Purine catabolism | 13 | 6.96e-02 | -0.291000 | 1.95e-01 |
| Signaling by ERBB2 | 49 | 7.06e-02 | -0.149000 | 1.97e-01 |
| Sensory processing of sound by outer hair cells of the cochlea | 40 | 7.07e-02 | -0.165000 | 1.97e-01 |
| Signaling by BMP | 24 | 7.12e-02 | 0.213000 | 1.98e-01 |
| NEP/NS2 Interacts with the Cellular Export Machinery | 32 | 7.16e-02 | -0.184000 | 1.99e-01 |
| Regulation of lipid metabolism by PPARalpha | 108 | 7.25e-02 | -0.100000 | 2.01e-01 |
| RIPK1-mediated regulated necrosis | 28 | 7.27e-02 | 0.196000 | 2.01e-01 |
| Regulation of necroptotic cell death | 28 | 7.27e-02 | 0.196000 | 2.01e-01 |
| Formation of the cornified envelope | 22 | 7.29e-02 | -0.221000 | 2.01e-01 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | 14 | 7.32e-02 | -0.277000 | 2.01e-01 |
| RAB GEFs exchange GTP for GDP on RABs | 88 | 7.38e-02 | -0.110000 | 2.02e-01 |
| Mismatch Repair | 15 | 7.44e-02 | -0.266000 | 2.03e-01 |
| PPARA activates gene expression | 106 | 7.44e-02 | -0.100000 | 2.03e-01 |
| Synthesis of glycosylphosphatidylinositol (GPI) | 18 | 7.44e-02 | -0.243000 | 2.03e-01 |
| Unblocking of NMDA receptors, glutamate binding and activation | 17 | 7.48e-02 | 0.250000 | 2.04e-01 |
| mRNA decay by 3’ to 5’ exoribonuclease | 16 | 7.52e-02 | -0.257000 | 2.04e-01 |
| Signaling by Insulin receptor | 66 | 7.62e-02 | -0.126000 | 2.07e-01 |
| Deadenylation-dependent mRNA decay | 53 | 7.64e-02 | -0.141000 | 2.07e-01 |
| Interactions of Rev with host cellular proteins | 37 | 7.65e-02 | -0.168000 | 2.07e-01 |
| CDC6 association with the ORC:origin complex | 11 | 7.72e-02 | 0.308000 | 2.08e-01 |
| GAB1 signalosome | 16 | 7.74e-02 | -0.255000 | 2.08e-01 |
| Programmed Cell Death | 195 | 7.87e-02 | -0.073100 | 2.11e-01 |
| Interleukin-2 signaling | 11 | 8.00e-02 | -0.305000 | 2.15e-01 |
| Response of EIF2AK1 (HRI) to heme deficiency | 15 | 8.04e-02 | 0.261000 | 2.15e-01 |
| Dual Incision in GG-NER | 41 | 8.19e-02 | -0.157000 | 2.19e-01 |
| Generic Transcription Pathway | 1105 | 8.24e-02 | 0.031100 | 2.20e-01 |
| G beta:gamma signalling through PI3Kgamma | 21 | 8.26e-02 | -0.219000 | 2.20e-01 |
| Interleukin receptor SHC signaling | 22 | 8.39e-02 | -0.213000 | 2.23e-01 |
| Negative regulation of FGFR1 signaling | 26 | 8.44e-02 | -0.196000 | 2.23e-01 |
| Nuclear import of Rev protein | 34 | 8.45e-02 | -0.171000 | 2.23e-01 |
| Association of TriC/CCT with target proteins during biosynthesis | 37 | 8.45e-02 | -0.164000 | 2.23e-01 |
| Metabolism of folate and pterines | 17 | 8.52e-02 | -0.241000 | 2.25e-01 |
| Glyoxylate metabolism and glycine degradation | 25 | 8.58e-02 | -0.199000 | 2.26e-01 |
| Suppression of phagosomal maturation | 13 | 8.58e-02 | -0.275000 | 2.26e-01 |
| TP53 Regulates Transcription of Cell Death Genes | 42 | 8.79e-02 | 0.152000 | 2.31e-01 |
| RHO GTPases activate KTN1 | 10 | 8.97e-02 | -0.310000 | 2.35e-01 |
| Cytosolic sensors of pathogen-associated DNA | 63 | 9.07e-02 | -0.123000 | 2.37e-01 |
| RNA Pol II CTD phosphorylation and interaction with CE | 27 | 9.13e-02 | -0.188000 | 2.38e-01 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | 27 | 9.13e-02 | -0.188000 | 2.38e-01 |
| Regulation of KIT signaling | 16 | 9.17e-02 | -0.244000 | 2.38e-01 |
| Signaling by NTRK1 (TRKA) | 110 | 9.18e-02 | 0.093100 | 2.38e-01 |
| Transcriptional regulation by RUNX3 | 95 | 9.21e-02 | -0.100000 | 2.39e-01 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer’s disease models | 19 | 9.33e-02 | -0.222000 | 2.41e-01 |
| Neurodegenerative Diseases | 19 | 9.33e-02 | -0.222000 | 2.41e-01 |
| O-linked glycosylation | 92 | 9.38e-02 | -0.101000 | 2.42e-01 |
| Signaling by FGFR | 74 | 9.56e-02 | -0.112000 | 2.46e-01 |
| Diseases of signal transduction by growth factor receptors and second messengers | 402 | 9.59e-02 | -0.048500 | 2.46e-01 |
| RAF-independent MAPK1/3 activation | 22 | 9.63e-02 | 0.205000 | 2.47e-01 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | 37 | 9.67e-02 | -0.158000 | 2.47e-01 |
| Transcriptional regulation of white adipocyte differentiation | 83 | 9.68e-02 | -0.105000 | 2.47e-01 |
| MyD88 deficiency (TLR2/4) | 14 | 9.72e-02 | -0.256000 | 2.48e-01 |
| Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon | 17 | 9.79e-02 | -0.232000 | 2.49e-01 |
| PTEN Regulation | 139 | 9.81e-02 | -0.081300 | 2.49e-01 |
| The activation of arylsulfatases | 10 | 1.00e-01 | -0.300000 | 2.54e-01 |
| Peroxisomal lipid metabolism | 26 | 1.00e-01 | -0.186000 | 2.54e-01 |
| mRNA Capping | 29 | 1.01e-01 | -0.176000 | 2.55e-01 |
| TNF signaling | 44 | 1.01e-01 | -0.143000 | 2.55e-01 |
| Assembly Of The HIV Virion | 16 | 1.01e-01 | -0.237000 | 2.55e-01 |
| Synthesis of PIPs at the early endosome membrane | 16 | 1.02e-01 | 0.236000 | 2.56e-01 |
| Cell-cell junction organization | 43 | 1.03e-01 | 0.144000 | 2.58e-01 |
| Defective HDR through Homologous Recombination (HRR) due to BRCA1 loss-of-function | 24 | 1.04e-01 | 0.192000 | 2.58e-01 |
| Defective HDR through Homologous Recombination (HRR) due to PALB2 loss of function | 24 | 1.04e-01 | 0.192000 | 2.58e-01 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | 24 | 1.04e-01 | 0.192000 | 2.58e-01 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | 24 | 1.04e-01 | 0.192000 | 2.58e-01 |
| Diseases of DNA Double-Strand Break Repair | 24 | 1.04e-01 | 0.192000 | 2.58e-01 |
| Transport of vitamins, nucleosides, and related molecules | 31 | 1.05e-01 | -0.168000 | 2.61e-01 |
| HDMs demethylate histones | 22 | 1.06e-01 | 0.199000 | 2.62e-01 |
| Cellular response to heat stress | 97 | 1.06e-01 | -0.095000 | 2.62e-01 |
| GPCR ligand binding | 244 | 1.07e-01 | 0.059900 | 2.65e-01 |
| Signaling by NOTCH1 | 71 | 1.08e-01 | 0.110000 | 2.65e-01 |
| Cytosolic iron-sulfur cluster assembly | 13 | 1.08e-01 | -0.258000 | 2.65e-01 |
| Termination of translesion DNA synthesis | 31 | 1.08e-01 | -0.167000 | 2.66e-01 |
| DNA Double Strand Break Response | 45 | 1.08e-01 | -0.138000 | 2.66e-01 |
| MET activates PTK2 signaling | 18 | 1.10e-01 | 0.217000 | 2.70e-01 |
| Nuclear Envelope Breakdown | 53 | 1.11e-01 | -0.126000 | 2.73e-01 |
| SHC1 events in EGFR signaling | 13 | 1.12e-01 | -0.255000 | 2.73e-01 |
| Signaling by ERBB4 | 53 | 1.12e-01 | -0.126000 | 2.73e-01 |
| Pyrimidine salvage | 10 | 1.13e-01 | -0.290000 | 2.74e-01 |
| Transcriptional activation of mitochondrial biogenesis | 53 | 1.14e-01 | -0.125000 | 2.77e-01 |
| G2/M Transition | 178 | 1.16e-01 | -0.068400 | 2.80e-01 |
| EPH-Ephrin signaling | 86 | 1.17e-01 | -0.097900 | 2.83e-01 |
| Formation of Incision Complex in GG-NER | 43 | 1.17e-01 | -0.138000 | 2.83e-01 |
| Receptor-type tyrosine-protein phosphatases | 14 | 1.18e-01 | 0.241000 | 2.86e-01 |
| MAPK1/MAPK3 signaling | 252 | 1.19e-01 | -0.057100 | 2.86e-01 |
| Acetylcholine Neurotransmitter Release Cycle | 13 | 1.19e-01 | 0.250000 | 2.86e-01 |
| Regulation of TP53 Activity through Acetylation | 29 | 1.20e-01 | -0.167000 | 2.86e-01 |
| Incretin synthesis, secretion, and inactivation | 14 | 1.20e-01 | -0.240000 | 2.86e-01 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | 14 | 1.20e-01 | -0.240000 | 2.86e-01 |
| MicroRNA (miRNA) biogenesis | 26 | 1.21e-01 | -0.176000 | 2.88e-01 |
| Receptor Mediated Mitophagy | 11 | 1.21e-01 | -0.270000 | 2.88e-01 |
| Signaling by FGFR2 in disease | 36 | 1.21e-01 | -0.149000 | 2.89e-01 |
| Chaperone Mediated Autophagy | 19 | 1.21e-01 | -0.205000 | 2.89e-01 |
| RHOB GTPase cycle | 67 | 1.24e-01 | 0.109000 | 2.94e-01 |
| Chromosome Maintenance | 97 | 1.24e-01 | -0.090400 | 2.94e-01 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | 28 | 1.24e-01 | -0.168000 | 2.94e-01 |
| RUNX2 regulates osteoblast differentiation | 22 | 1.25e-01 | 0.189000 | 2.95e-01 |
| PI3K/AKT Signaling in Cancer | 91 | 1.26e-01 | -0.092900 | 2.96e-01 |
| Arachidonic acid metabolism | 38 | 1.26e-01 | -0.144000 | 2.96e-01 |
| Mitotic G2-G2/M phases | 180 | 1.26e-01 | -0.066200 | 2.96e-01 |
| RNA Polymerase II Transcription | 1223 | 1.26e-01 | 0.026100 | 2.96e-01 |
| SARS-CoV-1 Infection | 48 | 1.26e-01 | -0.128000 | 2.96e-01 |
| Assembly of active LPL and LIPC lipase complexes | 13 | 1.27e-01 | -0.245000 | 2.96e-01 |
| Toll-like Receptor Cascades | 148 | 1.28e-01 | -0.072500 | 3.00e-01 |
| Retinoid metabolism and transport | 31 | 1.29e-01 | -0.157000 | 3.00e-01 |
| Advanced glycosylation endproduct receptor signaling | 13 | 1.29e-01 | -0.243000 | 3.00e-01 |
| Transcriptional Regulation by TP53 | 349 | 1.29e-01 | -0.047300 | 3.00e-01 |
| Pregnenolone biosynthesis | 10 | 1.29e-01 | -0.277000 | 3.00e-01 |
| Cytosolic sulfonation of small molecules | 20 | 1.29e-01 | -0.196000 | 3.00e-01 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | 44 | 1.31e-01 | -0.132000 | 3.03e-01 |
| VEGFA-VEGFR2 Pathway | 94 | 1.31e-01 | -0.090100 | 3.03e-01 |
| FGFR2 alternative splicing | 24 | 1.31e-01 | -0.178000 | 3.03e-01 |
| Spry regulation of FGF signaling | 16 | 1.32e-01 | -0.218000 | 3.03e-01 |
| Signaling by FGFR2 | 63 | 1.32e-01 | -0.110000 | 3.03e-01 |
| DNA Damage Bypass | 46 | 1.32e-01 | -0.128000 | 3.03e-01 |
| Semaphorin interactions | 63 | 1.32e-01 | -0.110000 | 3.03e-01 |
| RAC1 GTPase cycle | 177 | 1.33e-01 | 0.065500 | 3.04e-01 |
| DNA Double-Strand Break Repair | 132 | 1.33e-01 | -0.075700 | 3.04e-01 |
| DAP12 signaling | 28 | 1.33e-01 | -0.164000 | 3.04e-01 |
| DNA strand elongation | 32 | 1.34e-01 | -0.153000 | 3.05e-01 |
| Collagen formation | 86 | 1.35e-01 | -0.093300 | 3.07e-01 |
| Trafficking of GluR2-containing AMPA receptors | 15 | 1.36e-01 | -0.222000 | 3.09e-01 |
| Fanconi Anemia Pathway | 35 | 1.37e-01 | -0.145000 | 3.10e-01 |
| Other interleukin signaling | 22 | 1.37e-01 | -0.183000 | 3.11e-01 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | 26 | 1.38e-01 | 0.168000 | 3.12e-01 |
| Post-translational modification: synthesis of GPI-anchored proteins | 66 | 1.38e-01 | -0.106000 | 3.12e-01 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | 12 | 1.38e-01 | -0.247000 | 3.12e-01 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants | 15 | 1.39e-01 | 0.221000 | 3.12e-01 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer | 15 | 1.39e-01 | 0.221000 | 3.12e-01 |
| Export of Viral Ribonucleoproteins from Nucleus | 33 | 1.39e-01 | -0.149000 | 3.13e-01 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | 17 | 1.40e-01 | 0.207000 | 3.13e-01 |
| CRMPs in Sema3A signaling | 15 | 1.40e-01 | -0.220000 | 3.14e-01 |
| Transcription of the HIV genome | 67 | 1.41e-01 | -0.104000 | 3.14e-01 |
| Dopamine Neurotransmitter Release Cycle | 21 | 1.41e-01 | 0.186000 | 3.14e-01 |
| COPI-independent Golgi-to-ER retrograde traffic | 33 | 1.43e-01 | -0.147000 | 3.18e-01 |
| Signaling by KIT in disease | 20 | 1.45e-01 | -0.188000 | 3.22e-01 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | 20 | 1.45e-01 | -0.188000 | 3.22e-01 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | 34 | 1.47e-01 | -0.144000 | 3.26e-01 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | 37 | 1.51e-01 | -0.137000 | 3.33e-01 |
| LGI-ADAM interactions | 10 | 1.52e-01 | -0.262000 | 3.35e-01 |
| MAPK targets/ Nuclear events mediated by MAP kinases | 31 | 1.54e-01 | 0.148000 | 3.39e-01 |
| Translesion Synthesis by POLH | 18 | 1.54e-01 | -0.194000 | 3.39e-01 |
| Cleavage of the damaged purine | 18 | 1.55e-01 | -0.194000 | 3.39e-01 |
| Depurination | 18 | 1.55e-01 | -0.194000 | 3.39e-01 |
| Recognition and association of DNA glycosylase with site containing an affected purine | 18 | 1.55e-01 | -0.194000 | 3.39e-01 |
| Gap junction trafficking | 18 | 1.55e-01 | -0.194000 | 3.39e-01 |
| Mitochondrial calcium ion transport | 22 | 1.55e-01 | -0.175000 | 3.39e-01 |
| RHOBTB3 ATPase cycle | 10 | 1.56e-01 | -0.259000 | 3.41e-01 |
| Interleukin-6 family signaling | 22 | 1.57e-01 | 0.174000 | 3.41e-01 |
| Downregulation of ERBB2 signaling | 28 | 1.57e-01 | -0.155000 | 3.41e-01 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | 40 | 1.58e-01 | -0.129000 | 3.42e-01 |
| Signaling by RAS mutants | 40 | 1.58e-01 | -0.129000 | 3.42e-01 |
| Signaling by moderate kinase activity BRAF mutants | 40 | 1.58e-01 | -0.129000 | 3.42e-01 |
| Signaling downstream of RAS mutants | 40 | 1.58e-01 | -0.129000 | 3.42e-01 |
| Signal amplification | 28 | 1.58e-01 | -0.154000 | 3.42e-01 |
| Serotonin Neurotransmitter Release Cycle | 16 | 1.60e-01 | 0.203000 | 3.44e-01 |
| Assembly and cell surface presentation of NMDA receptors | 22 | 1.60e-01 | 0.173000 | 3.45e-01 |
| Lagging Strand Synthesis | 20 | 1.62e-01 | -0.181000 | 3.48e-01 |
| Telomere C-strand (Lagging Strand) Synthesis | 34 | 1.62e-01 | -0.138000 | 3.48e-01 |
| Metabolism of steroid hormones | 24 | 1.62e-01 | -0.165000 | 3.48e-01 |
| Synthesis of IP2, IP, and Ins in the cytosol | 13 | 1.66e-01 | 0.222000 | 3.55e-01 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | 16 | 1.67e-01 | -0.200000 | 3.57e-01 |
| Gap junction degradation | 10 | 1.68e-01 | -0.252000 | 3.58e-01 |
| Collagen chain trimerization | 42 | 1.68e-01 | 0.123000 | 3.58e-01 |
| Regulated proteolysis of p75NTR | 11 | 1.68e-01 | -0.240000 | 3.58e-01 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | 25 | 1.69e-01 | -0.159000 | 3.59e-01 |
| Activation of gene expression by SREBF (SREBP) | 42 | 1.69e-01 | -0.123000 | 3.59e-01 |
| IRAK4 deficiency (TLR2/4) | 15 | 1.71e-01 | -0.204000 | 3.61e-01 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | 25 | 1.73e-01 | 0.157000 | 3.66e-01 |
| Metabolism of water-soluble vitamins and cofactors | 111 | 1.73e-01 | -0.074800 | 3.66e-01 |
| Chondroitin sulfate biosynthesis | 16 | 1.74e-01 | -0.196000 | 3.68e-01 |
| Initiation of Nuclear Envelope (NE) Reformation | 19 | 1.75e-01 | 0.180000 | 3.68e-01 |
| RNA Polymerase II Pre-transcription Events | 78 | 1.76e-01 | -0.088600 | 3.69e-01 |
| Pre-NOTCH Transcription and Translation | 43 | 1.76e-01 | 0.119000 | 3.69e-01 |
| EPHB-mediated forward signaling | 32 | 1.77e-01 | -0.138000 | 3.69e-01 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | 57 | 1.77e-01 | 0.103000 | 3.69e-01 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | 57 | 1.77e-01 | 0.103000 | 3.69e-01 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | 57 | 1.77e-01 | 0.103000 | 3.69e-01 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | 57 | 1.77e-01 | 0.103000 | 3.69e-01 |
| Signaling by NOTCH1 in Cancer | 57 | 1.77e-01 | 0.103000 | 3.69e-01 |
| TNFR1-induced NFkappaB signaling pathway | 26 | 1.78e-01 | -0.153000 | 3.69e-01 |
| Energy dependent regulation of mTOR by LKB1-AMPK | 29 | 1.78e-01 | -0.145000 | 3.69e-01 |
| CASP8 activity is inhibited | 10 | 1.78e-01 | 0.246000 | 3.69e-01 |
| Dimerization of procaspase-8 | 10 | 1.78e-01 | 0.246000 | 3.69e-01 |
| Regulation by c-FLIP | 10 | 1.78e-01 | 0.246000 | 3.69e-01 |
| Glycogen breakdown (glycogenolysis) | 15 | 1.79e-01 | -0.200000 | 3.69e-01 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | 55 | 1.80e-01 | -0.105000 | 3.71e-01 |
| NS1 Mediated Effects on Host Pathways | 40 | 1.80e-01 | -0.122000 | 3.71e-01 |
| Gap junction trafficking and regulation | 20 | 1.81e-01 | -0.173000 | 3.72e-01 |
| Transcriptional regulation of granulopoiesis | 39 | 1.82e-01 | 0.123000 | 3.74e-01 |
| Regulation of HSF1-mediated heat shock response | 79 | 1.83e-01 | -0.086600 | 3.75e-01 |
| mRNA decay by 5’ to 3’ exoribonuclease | 15 | 1.83e-01 | -0.198000 | 3.75e-01 |
| Integrin signaling | 24 | 1.83e-01 | -0.157000 | 3.75e-01 |
| Effects of PIP2 hydrolysis | 24 | 1.86e-01 | 0.156000 | 3.79e-01 |
| Activation of NMDA receptors and postsynaptic events | 69 | 1.87e-01 | 0.092000 | 3.80e-01 |
| Josephin domain DUBs | 10 | 1.87e-01 | -0.241000 | 3.81e-01 |
| Deposition of new CENPA-containing nucleosomes at the centromere | 34 | 1.88e-01 | 0.131000 | 3.81e-01 |
| Nucleosome assembly | 34 | 1.88e-01 | 0.131000 | 3.81e-01 |
| Other semaphorin interactions | 19 | 1.88e-01 | -0.174000 | 3.81e-01 |
| Glycogen synthesis | 15 | 1.89e-01 | -0.196000 | 3.83e-01 |
| Signaling by SCF-KIT | 43 | 1.91e-01 | -0.115000 | 3.87e-01 |
| Negative regulation of the PI3K/AKT network | 98 | 1.92e-01 | -0.076400 | 3.87e-01 |
| Purine salvage | 13 | 1.93e-01 | -0.208000 | 3.89e-01 |
| ADP signalling through P2Y purinoceptor 1 | 21 | 1.94e-01 | -0.164000 | 3.90e-01 |
| RMTs methylate histone arginines | 35 | 1.94e-01 | -0.127000 | 3.90e-01 |
| Synthesis of PIPs at the late endosome membrane | 11 | 1.95e-01 | 0.226000 | 3.92e-01 |
| ALK mutants bind TKIs | 12 | 1.96e-01 | 0.216000 | 3.93e-01 |
| Triglyceride catabolism | 16 | 1.96e-01 | -0.187000 | 3.93e-01 |
| SUMOylation of chromatin organization proteins | 57 | 1.97e-01 | -0.098900 | 3.93e-01 |
| Muscle contraction | 158 | 1.97e-01 | 0.059500 | 3.93e-01 |
| Telomere Extension By Telomerase | 21 | 1.99e-01 | -0.162000 | 3.97e-01 |
| Killing mechanisms | 10 | 2.00e-01 | -0.234000 | 3.97e-01 |
| WNT5:FZD7-mediated leishmania damping | 10 | 2.00e-01 | -0.234000 | 3.97e-01 |
| Cell Cycle | 608 | 2.01e-01 | -0.030400 | 4.00e-01 |
| Signaling by NOTCH | 181 | 2.03e-01 | -0.054900 | 4.02e-01 |
| Methylation | 13 | 2.03e-01 | -0.204000 | 4.02e-01 |
| Regulation of localization of FOXO transcription factors | 12 | 2.04e-01 | -0.212000 | 4.04e-01 |
| TNFR1-induced proapoptotic signaling | 13 | 2.05e-01 | -0.203000 | 4.04e-01 |
| CTLA4 inhibitory signaling | 20 | 2.05e-01 | -0.164000 | 4.04e-01 |
| RUNX3 regulates p14-ARF | 10 | 2.06e-01 | -0.231000 | 4.05e-01 |
| Dectin-2 family | 14 | 2.08e-01 | -0.194000 | 4.07e-01 |
| SUMOylation of immune response proteins | 11 | 2.08e-01 | -0.219000 | 4.07e-01 |
| Signaling by PDGFRA extracellular domain mutants | 12 | 2.08e-01 | -0.210000 | 4.07e-01 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | 12 | 2.08e-01 | -0.210000 | 4.07e-01 |
| Diseases of DNA repair | 33 | 2.08e-01 | 0.127000 | 4.07e-01 |
| RHO GTPases activate CIT | 19 | 2.09e-01 | 0.166000 | 4.09e-01 |
| M Phase | 353 | 2.11e-01 | -0.038800 | 4.11e-01 |
| ERBB2 Regulates Cell Motility | 14 | 2.12e-01 | -0.193000 | 4.12e-01 |
| Cyclin A/B1/B2 associated events during G2/M transition | 23 | 2.12e-01 | 0.150000 | 4.12e-01 |
| NOD1/2 Signaling Pathway | 32 | 2.13e-01 | 0.127000 | 4.12e-01 |
| RUNX2 regulates bone development | 28 | 2.13e-01 | 0.136000 | 4.12e-01 |
| Pentose phosphate pathway | 13 | 2.13e-01 | -0.200000 | 4.12e-01 |
| Myogenesis | 24 | 2.13e-01 | 0.147000 | 4.12e-01 |
| FLT3 Signaling | 38 | 2.13e-01 | -0.117000 | 4.12e-01 |
| Synthesis, secretion, and deacylation of Ghrelin | 14 | 2.13e-01 | -0.192000 | 4.12e-01 |
| RNA polymerase II transcribes snRNA genes | 71 | 2.14e-01 | -0.085400 | 4.12e-01 |
| L1CAM interactions | 92 | 2.15e-01 | -0.074800 | 4.14e-01 |
| Signaling by Receptor Tyrosine Kinases | 472 | 2.20e-01 | -0.033000 | 4.23e-01 |
| Homologous DNA Pairing and Strand Exchange | 42 | 2.21e-01 | 0.109000 | 4.24e-01 |
| Transcriptional Regulation by E2F6 | 34 | 2.21e-01 | 0.121000 | 4.24e-01 |
| Constitutive Signaling by AKT1 E17K in Cancer | 26 | 2.22e-01 | -0.138000 | 4.25e-01 |
| Presynaptic phase of homologous DNA pairing and strand exchange | 39 | 2.22e-01 | 0.113000 | 4.25e-01 |
| Synthesis of pyrophosphates in the cytosol | 10 | 2.25e-01 | -0.222000 | 4.29e-01 |
| Regulation of insulin secretion | 64 | 2.25e-01 | 0.087700 | 4.29e-01 |
| RHOQ GTPase cycle | 58 | 2.28e-01 | 0.091600 | 4.32e-01 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | 46 | 2.28e-01 | 0.103000 | 4.32e-01 |
| Transmission across Chemical Synapses | 188 | 2.28e-01 | 0.051000 | 4.32e-01 |
| Signaling by FGFR1 | 42 | 2.28e-01 | -0.108000 | 4.32e-01 |
| Transport of Mature Transcript to Cytoplasm | 81 | 2.28e-01 | -0.077500 | 4.32e-01 |
| TICAM1-dependent activation of IRF3/IRF7 | 12 | 2.28e-01 | -0.201000 | 4.32e-01 |
| KSRP (KHSRP) binds and destabilizes mRNA | 17 | 2.29e-01 | -0.168000 | 4.32e-01 |
| Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) | 11 | 2.29e-01 | -0.209000 | 4.32e-01 |
| Diseases of hemostasis | 11 | 2.29e-01 | -0.209000 | 4.32e-01 |
| CD209 (DC-SIGN) signaling | 20 | 2.30e-01 | -0.155000 | 4.33e-01 |
| Collagen biosynthesis and modifying enzymes | 65 | 2.31e-01 | -0.085900 | 4.34e-01 |
| Cohesin Loading onto Chromatin | 10 | 2.33e-01 | 0.218000 | 4.36e-01 |
| SUMOylation of DNA methylation proteins | 16 | 2.33e-01 | 0.172000 | 4.36e-01 |
| Constitutive Signaling by Aberrant PI3K in Cancer | 64 | 2.34e-01 | -0.086100 | 4.38e-01 |
| TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | 16 | 2.36e-01 | -0.171000 | 4.41e-01 |
| RHOU GTPase cycle | 40 | 2.36e-01 | -0.108000 | 4.41e-01 |
| InlB-mediated entry of Listeria monocytogenes into host cell | 14 | 2.37e-01 | -0.183000 | 4.41e-01 |
| Signaling by VEGF | 103 | 2.38e-01 | -0.067300 | 4.43e-01 |
| Retrograde transport at the Trans-Golgi-Network | 49 | 2.38e-01 | -0.097400 | 4.43e-01 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | 72 | 2.39e-01 | -0.080300 | 4.44e-01 |
| Base-Excision Repair, AP Site Formation | 25 | 2.40e-01 | -0.136000 | 4.46e-01 |
| Phase I - Functionalization of compounds | 73 | 2.41e-01 | -0.079500 | 4.46e-01 |
| Xenobiotics | 10 | 2.42e-01 | 0.214000 | 4.47e-01 |
| Aspartate and asparagine metabolism | 10 | 2.49e-01 | 0.210000 | 4.60e-01 |
| Ca-dependent events | 35 | 2.49e-01 | -0.113000 | 4.60e-01 |
| Intrinsic Pathway for Apoptosis | 55 | 2.50e-01 | -0.089600 | 4.61e-01 |
| Neurotransmitter release cycle | 38 | 2.51e-01 | 0.108000 | 4.61e-01 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | 13 | 2.51e-01 | -0.184000 | 4.61e-01 |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | 10 | 2.51e-01 | 0.210000 | 4.61e-01 |
| Membrane binding and targetting of GAG proteins | 14 | 2.51e-01 | -0.177000 | 4.61e-01 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | 14 | 2.51e-01 | -0.177000 | 4.61e-01 |
| Signaling by NTRKs | 127 | 2.53e-01 | 0.058700 | 4.63e-01 |
| SUMOylation of RNA binding proteins | 47 | 2.54e-01 | -0.096300 | 4.63e-01 |
| Prefoldin mediated transfer of substrate to CCT/TriC | 25 | 2.56e-01 | -0.131000 | 4.67e-01 |
| Signaling by FGFR in disease | 55 | 2.56e-01 | -0.088500 | 4.67e-01 |
| Norepinephrine Neurotransmitter Release Cycle | 15 | 2.59e-01 | 0.168000 | 4.71e-01 |
| Signaling by NOTCH3 | 46 | 2.59e-01 | 0.096200 | 4.71e-01 |
| Keratinization | 28 | 2.59e-01 | -0.123000 | 4.71e-01 |
| Signaling by EGFR | 48 | 2.60e-01 | -0.094100 | 4.71e-01 |
| RHO GTPases Activate Formins | 117 | 2.60e-01 | 0.060300 | 4.71e-01 |
| O-glycosylation of TSR domain-containing proteins | 37 | 2.61e-01 | -0.107000 | 4.72e-01 |
| Cell Cycle, Mitotic | 493 | 2.63e-01 | -0.029500 | 4.75e-01 |
| Signaling by NODAL | 15 | 2.65e-01 | -0.166000 | 4.78e-01 |
| HATs acetylate histones | 86 | 2.66e-01 | -0.069400 | 4.79e-01 |
| CaM pathway | 33 | 2.67e-01 | -0.112000 | 4.80e-01 |
| Calmodulin induced events | 33 | 2.67e-01 | -0.112000 | 4.80e-01 |
| RHOH GTPase cycle | 33 | 2.69e-01 | -0.111000 | 4.82e-01 |
| ERBB2 Activates PTK6 Signaling | 12 | 2.71e-01 | -0.184000 | 4.85e-01 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | 91 | 2.72e-01 | -0.066700 | 4.86e-01 |
| Translation of Structural Proteins | 29 | 2.72e-01 | -0.118000 | 4.86e-01 |
| Potential therapeutics for SARS | 81 | 2.73e-01 | -0.070500 | 4.87e-01 |
| Negative regulation of FGFR3 signaling | 25 | 2.73e-01 | -0.127000 | 4.88e-01 |
| Regulation of TLR by endogenous ligand | 15 | 2.74e-01 | -0.163000 | 4.88e-01 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | 28 | 2.74e-01 | -0.119000 | 4.88e-01 |
| Regulation of beta-cell development | 22 | 2.74e-01 | 0.135000 | 4.88e-01 |
| Notch-HLH transcription pathway | 28 | 2.75e-01 | 0.119000 | 4.88e-01 |
| Phase 4 - resting membrane potential | 13 | 2.75e-01 | 0.175000 | 4.88e-01 |
| Branched-chain amino acid catabolism | 21 | 2.76e-01 | -0.137000 | 4.88e-01 |
| Visual phototransduction | 67 | 2.77e-01 | -0.076900 | 4.88e-01 |
| PKMTs methylate histone lysines | 43 | 2.77e-01 | 0.095800 | 4.88e-01 |
| Epigenetic regulation of gene expression | 97 | 2.77e-01 | 0.063800 | 4.88e-01 |
| Disorders of Developmental Biology | 13 | 2.78e-01 | -0.174000 | 4.88e-01 |
| Disorders of Nervous System Development | 13 | 2.78e-01 | -0.174000 | 4.88e-01 |
| Loss of function of MECP2 in Rett syndrome | 13 | 2.78e-01 | -0.174000 | 4.88e-01 |
| Pervasive developmental disorders | 13 | 2.78e-01 | -0.174000 | 4.88e-01 |
| Mitotic Telophase/Cytokinesis | 13 | 2.79e-01 | 0.173000 | 4.90e-01 |
| PECAM1 interactions | 12 | 2.80e-01 | -0.180000 | 4.91e-01 |
| AKT phosphorylates targets in the nucleus | 10 | 2.82e-01 | -0.197000 | 4.93e-01 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | 16 | 2.82e-01 | -0.155000 | 4.94e-01 |
| Signaling by NTRK3 (TRKC) | 17 | 2.83e-01 | -0.150000 | 4.95e-01 |
| Uptake and actions of bacterial toxins | 26 | 2.84e-01 | -0.121000 | 4.96e-01 |
| mitochondrial fatty acid beta-oxidation of saturated fatty acids | 10 | 2.86e-01 | -0.195000 | 4.98e-01 |
| Dissolution of Fibrin Clot | 11 | 2.89e-01 | -0.185000 | 5.02e-01 |
| Translesion synthesis by REV1 | 16 | 2.89e-01 | -0.153000 | 5.02e-01 |
| Repression of WNT target genes | 14 | 2.91e-01 | 0.163000 | 5.05e-01 |
| Negative regulation of FGFR4 signaling | 25 | 2.92e-01 | -0.122000 | 5.05e-01 |
| Adherens junctions interactions | 23 | 2.92e-01 | 0.127000 | 5.05e-01 |
| Heme biosynthesis | 13 | 2.96e-01 | -0.167000 | 5.12e-01 |
| Synthesis of bile acids and bile salts | 26 | 2.97e-01 | 0.118000 | 5.12e-01 |
| Keratan sulfate/keratin metabolism | 33 | 2.97e-01 | -0.105000 | 5.12e-01 |
| Aggrephagy | 21 | 2.98e-01 | -0.131000 | 5.14e-01 |
| Cellular Senescence | 138 | 2.99e-01 | 0.051200 | 5.15e-01 |
| Prostacyclin signalling through prostacyclin receptor | 15 | 3.02e-01 | -0.154000 | 5.18e-01 |
| Cell-extracellular matrix interactions | 16 | 3.03e-01 | 0.149000 | 5.20e-01 |
| Platelet sensitization by LDL | 17 | 3.03e-01 | -0.144000 | 5.20e-01 |
| Post NMDA receptor activation events | 57 | 3.05e-01 | 0.078500 | 5.23e-01 |
| NR1H2 and NR1H3-mediated signaling | 41 | 3.06e-01 | -0.092500 | 5.23e-01 |
| ATF6 (ATF6-alpha) activates chaperones | 12 | 3.06e-01 | -0.171000 | 5.23e-01 |
| tRNA modification in the nucleus and cytosol | 43 | 3.07e-01 | -0.090000 | 5.24e-01 |
| Defective B3GALTL causes PpS | 36 | 3.12e-01 | -0.097300 | 5.32e-01 |
| Signalling to RAS | 20 | 3.13e-01 | 0.130000 | 5.32e-01 |
| The phototransduction cascade | 24 | 3.14e-01 | 0.119000 | 5.33e-01 |
| Signaling by GPCR | 457 | 3.14e-01 | 0.027500 | 5.33e-01 |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | 11 | 3.15e-01 | -0.175000 | 5.34e-01 |
| Biotin transport and metabolism | 11 | 3.16e-01 | -0.175000 | 5.36e-01 |
| RND2 GTPase cycle | 39 | 3.17e-01 | -0.092600 | 5.37e-01 |
| MAPK3 (ERK1) activation | 10 | 3.18e-01 | 0.182000 | 5.37e-01 |
| Netrin-1 signaling | 43 | 3.20e-01 | 0.087700 | 5.40e-01 |
| Synthesis of bile acids and bile salts via 24-hydroxycholesterol | 10 | 3.22e-01 | 0.181000 | 5.43e-01 |
| Signaling by Rho GTPases | 606 | 3.22e-01 | 0.023600 | 5.43e-01 |
| Signaling by Nuclear Receptors | 225 | 3.23e-01 | -0.038300 | 5.44e-01 |
| AKT phosphorylates targets in the cytosol | 14 | 3.25e-01 | -0.152000 | 5.46e-01 |
| Signaling by Leptin | 11 | 3.25e-01 | 0.171000 | 5.46e-01 |
| HSF1 activation | 26 | 3.28e-01 | -0.111000 | 5.50e-01 |
| NRIF signals cell death from the nucleus | 16 | 3.28e-01 | -0.141000 | 5.50e-01 |
| Regulation of innate immune responses to cytosolic DNA | 14 | 3.30e-01 | -0.150000 | 5.52e-01 |
| Polymerase switching on the C-strand of the telomere | 26 | 3.30e-01 | -0.110000 | 5.52e-01 |
| Sema4D induced cell migration and growth-cone collapse | 20 | 3.31e-01 | 0.126000 | 5.52e-01 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | 25 | 3.31e-01 | -0.112000 | 5.52e-01 |
| p130Cas linkage to MAPK signaling for integrins | 12 | 3.32e-01 | -0.162000 | 5.52e-01 |
| Ion channel transport | 138 | 3.32e-01 | -0.047800 | 5.52e-01 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | 24 | 3.32e-01 | -0.114000 | 5.52e-01 |
| Interleukin-4 and Interleukin-13 signaling | 96 | 3.33e-01 | 0.057200 | 5.53e-01 |
| Miscellaneous transport and binding events | 21 | 3.34e-01 | -0.122000 | 5.54e-01 |
| RAB geranylgeranylation | 60 | 3.35e-01 | -0.072000 | 5.54e-01 |
| Glucagon-type ligand receptors | 23 | 3.36e-01 | -0.116000 | 5.57e-01 |
| RHO GTPases Activate ROCKs | 19 | 3.37e-01 | 0.127000 | 5.57e-01 |
| RA biosynthesis pathway | 18 | 3.41e-01 | -0.130000 | 5.63e-01 |
| Pexophagy | 11 | 3.45e-01 | -0.164000 | 5.69e-01 |
| Signaling by RAF1 mutants | 36 | 3.47e-01 | -0.090700 | 5.71e-01 |
| Regulation of TP53 Degradation | 35 | 3.48e-01 | -0.091700 | 5.71e-01 |
| GPCR downstream signalling | 414 | 3.48e-01 | 0.026900 | 5.71e-01 |
| Negative regulation of FGFR2 signaling | 27 | 3.49e-01 | -0.104000 | 5.73e-01 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | 12 | 3.52e-01 | -0.155000 | 5.76e-01 |
| Neuronal System | 283 | 3.52e-01 | 0.032200 | 5.76e-01 |
| Activation of AMPK downstream of NMDARs | 10 | 3.52e-01 | 0.170000 | 5.77e-01 |
| Cytochrome c-mediated apoptotic response | 13 | 3.54e-01 | 0.149000 | 5.78e-01 |
| Oxidative Stress Induced Senescence | 73 | 3.55e-01 | 0.062700 | 5.79e-01 |
| Cargo trafficking to the periciliary membrane | 46 | 3.58e-01 | -0.078400 | 5.83e-01 |
| Processing of Capped Intronless Pre-mRNA | 28 | 3.58e-01 | -0.100000 | 5.83e-01 |
| TP53 Regulates Transcription of DNA Repair Genes | 61 | 3.59e-01 | -0.067900 | 5.84e-01 |
| BBSome-mediated cargo-targeting to cilium | 21 | 3.59e-01 | -0.116000 | 5.84e-01 |
| Signaling by Rho GTPases, Miro GTPases and RHOBTB3 | 622 | 3.60e-01 | 0.021500 | 5.84e-01 |
| ECM proteoglycans | 48 | 3.60e-01 | -0.076400 | 5.84e-01 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | 16 | 3.62e-01 | -0.132000 | 5.86e-01 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | 32 | 3.64e-01 | 0.092800 | 5.88e-01 |
| Thromboxane signalling through TP receptor | 20 | 3.64e-01 | -0.117000 | 5.88e-01 |
| Lewis blood group biosynthesis | 12 | 3.66e-01 | -0.151000 | 5.90e-01 |
| PI3K Cascade | 35 | 3.66e-01 | -0.088300 | 5.91e-01 |
| Signaling by Retinoic Acid | 38 | 3.67e-01 | -0.084600 | 5.91e-01 |
| SHC1 events in ERBB2 signaling | 21 | 3.67e-01 | -0.114000 | 5.91e-01 |
| Signaling by EGFR in Cancer | 24 | 3.68e-01 | -0.106000 | 5.92e-01 |
| Regulation of RUNX1 Expression and Activity | 18 | 3.70e-01 | 0.122000 | 5.93e-01 |
| Cleavage of the damaged pyrimidine | 23 | 3.74e-01 | -0.107000 | 5.98e-01 |
| Depyrimidination | 23 | 3.74e-01 | -0.107000 | 5.98e-01 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | 23 | 3.74e-01 | -0.107000 | 5.98e-01 |
| GRB2 events in ERBB2 signaling | 15 | 3.75e-01 | -0.132000 | 5.99e-01 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | 30 | 3.75e-01 | -0.093500 | 5.99e-01 |
| Activation of ATR in response to replication stress | 35 | 3.76e-01 | 0.086500 | 6.00e-01 |
| Regulation of pyruvate dehydrogenase (PDH) complex | 15 | 3.76e-01 | -0.132000 | 6.00e-01 |
| Erythropoietin activates RAS | 13 | 3.77e-01 | -0.142000 | 6.00e-01 |
| FOXO-mediated transcription | 58 | 3.78e-01 | 0.067000 | 6.01e-01 |
| Resolution of D-Loop Structures | 33 | 3.84e-01 | 0.087600 | 6.09e-01 |
| SLBP independent Processing of Histone Pre-mRNAs | 10 | 3.84e-01 | -0.159000 | 6.09e-01 |
| Activation of BAD and translocation to mitochondria | 15 | 3.85e-01 | -0.130000 | 6.09e-01 |
| Circadian Clock | 68 | 3.88e-01 | 0.060600 | 6.13e-01 |
| Glutathione synthesis and recycling | 11 | 3.88e-01 | -0.150000 | 6.13e-01 |
| RNA Polymerase I Promoter Opening | 13 | 3.90e-01 | -0.138000 | 6.15e-01 |
| Gene expression (Transcription) | 1356 | 3.91e-01 | 0.014000 | 6.16e-01 |
| Neurexins and neuroligins | 47 | 3.91e-01 | -0.072300 | 6.16e-01 |
| Formation of apoptosome | 11 | 3.92e-01 | 0.149000 | 6.16e-01 |
| Regulation of the apoptosome activity | 11 | 3.92e-01 | 0.149000 | 6.16e-01 |
| Carnitine metabolism | 12 | 3.93e-01 | -0.142000 | 6.17e-01 |
| Packaging Of Telomere Ends | 15 | 3.93e-01 | -0.127000 | 6.17e-01 |
| B-WICH complex positively regulates rRNA expression | 41 | 3.94e-01 | -0.077000 | 6.17e-01 |
| Regulation of FOXO transcriptional activity by acetylation | 10 | 3.94e-01 | -0.156000 | 6.17e-01 |
| Glucagon signaling in metabolic regulation | 28 | 3.95e-01 | -0.092900 | 6.17e-01 |
| Pyroptosis | 25 | 3.95e-01 | -0.098200 | 6.17e-01 |
| Synthesis of PIPs at the Golgi membrane | 15 | 3.96e-01 | -0.127000 | 6.18e-01 |
| Triglyceride metabolism | 25 | 3.97e-01 | -0.097900 | 6.18e-01 |
| Opioid Signalling | 82 | 4.01e-01 | -0.053700 | 6.24e-01 |
| Activation of SMO | 16 | 4.01e-01 | -0.121000 | 6.24e-01 |
| Translesion synthesis by POLK | 17 | 4.03e-01 | -0.117000 | 6.26e-01 |
| RHOV GTPase cycle | 35 | 4.04e-01 | 0.081600 | 6.27e-01 |
| E2F mediated regulation of DNA replication | 22 | 4.05e-01 | 0.103000 | 6.28e-01 |
| Metabolism of Angiotensinogen to Angiotensins | 15 | 4.07e-01 | -0.124000 | 6.31e-01 |
| Inactivation, recovery and regulation of the phototransduction cascade | 23 | 4.10e-01 | 0.099300 | 6.34e-01 |
| Elevation of cytosolic Ca2+ levels | 13 | 4.17e-01 | -0.130000 | 6.44e-01 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | 30 | 4.17e-01 | -0.085600 | 6.44e-01 |
| Nuclear events stimulated by ALK signaling in cancer | 19 | 4.24e-01 | -0.106000 | 6.54e-01 |
| Aflatoxin activation and detoxification | 13 | 4.26e-01 | -0.127000 | 6.56e-01 |
| Signaling by Activin | 14 | 4.27e-01 | 0.123000 | 6.56e-01 |
| Prolactin receptor signaling | 11 | 4.27e-01 | -0.138000 | 6.56e-01 |
| Neurotransmitter receptors and postsynaptic signal transmission | 138 | 4.29e-01 | 0.039000 | 6.59e-01 |
| Activation of BH3-only proteins | 30 | 4.32e-01 | -0.083000 | 6.62e-01 |
| Processing of SMDT1 | 15 | 4.34e-01 | -0.117000 | 6.64e-01 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | 23 | 4.35e-01 | -0.094100 | 6.65e-01 |
| PI3K events in ERBB2 signaling | 15 | 4.35e-01 | -0.116000 | 6.65e-01 |
| RHO GTPases activate PAKs | 21 | 4.36e-01 | 0.098200 | 6.66e-01 |
| ERKs are inactivated | 13 | 4.41e-01 | -0.123000 | 6.73e-01 |
| O-linked glycosylation of mucins | 46 | 4.42e-01 | -0.065500 | 6.74e-01 |
| Phase 2 - plateau phase | 10 | 4.42e-01 | 0.140000 | 6.74e-01 |
| Signaling by TGFB family members | 99 | 4.44e-01 | 0.044600 | 6.75e-01 |
| Regulation of MECP2 expression and activity | 30 | 4.46e-01 | 0.080400 | 6.77e-01 |
| Adrenaline,noradrenaline inhibits insulin secretion | 24 | 4.46e-01 | 0.089800 | 6.77e-01 |
| G beta:gamma signalling through BTK | 14 | 4.46e-01 | -0.118000 | 6.77e-01 |
| RHOBTB2 GTPase cycle | 23 | 4.49e-01 | 0.091100 | 6.81e-01 |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | 14 | 4.51e-01 | -0.116000 | 6.83e-01 |
| Phospholipase C-mediated cascade; FGFR2 | 11 | 4.52e-01 | 0.131000 | 6.83e-01 |
| MET promotes cell motility | 29 | 4.53e-01 | 0.080500 | 6.84e-01 |
| BMAL1:CLOCK,NPAS2 activates circadian gene expression | 26 | 4.53e-01 | 0.085000 | 6.84e-01 |
| Downregulation of ERBB2:ERBB3 signaling | 13 | 4.54e-01 | -0.120000 | 6.84e-01 |
| Nucleotide-like (purinergic) receptors | 15 | 4.55e-01 | -0.111000 | 6.85e-01 |
| Frs2-mediated activation | 12 | 4.55e-01 | -0.124000 | 6.85e-01 |
| RHOBTB GTPase Cycle | 35 | 4.58e-01 | 0.072500 | 6.86e-01 |
| TRP channels | 17 | 4.59e-01 | 0.104000 | 6.86e-01 |
| IRS-mediated signalling | 39 | 4.61e-01 | -0.068300 | 6.86e-01 |
| RNA Polymerase I Transcription Termination | 30 | 4.61e-01 | -0.077800 | 6.86e-01 |
| Endosomal/Vacuolar pathway | 11 | 4.61e-01 | 0.128000 | 6.86e-01 |
| SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs | 11 | 4.63e-01 | -0.128000 | 6.86e-01 |
| G beta:gamma signalling through CDC42 | 16 | 4.63e-01 | -0.106000 | 6.86e-01 |
| Interleukin-35 Signalling | 11 | 4.63e-01 | -0.128000 | 6.86e-01 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | 15 | 4.63e-01 | -0.109000 | 6.86e-01 |
| Signaling by FLT3 fusion proteins | 19 | 4.64e-01 | 0.097100 | 6.86e-01 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | 32 | 4.64e-01 | 0.074800 | 6.86e-01 |
| APC/C:Cdc20 mediated degradation of Cyclin B | 24 | 4.64e-01 | -0.086300 | 6.86e-01 |
| HIV Transcription Initiation | 45 | 4.65e-01 | -0.063000 | 6.86e-01 |
| RNA Polymerase II HIV Promoter Escape | 45 | 4.65e-01 | -0.063000 | 6.86e-01 |
| RNA Polymerase II Promoter Escape | 45 | 4.65e-01 | -0.063000 | 6.86e-01 |
| RNA Polymerase II Transcription Initiation | 45 | 4.65e-01 | -0.063000 | 6.86e-01 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | 45 | 4.65e-01 | -0.063000 | 6.86e-01 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | 45 | 4.65e-01 | -0.063000 | 6.86e-01 |
| PLC beta mediated events | 47 | 4.66e-01 | -0.061500 | 6.87e-01 |
| PKA activation in glucagon signalling | 16 | 4.66e-01 | -0.105000 | 6.87e-01 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | 68 | 4.67e-01 | -0.051000 | 6.87e-01 |
| Nonhomologous End-Joining (NHEJ) | 37 | 4.70e-01 | -0.068600 | 6.91e-01 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | 44 | 4.71e-01 | -0.062800 | 6.91e-01 |
| Regulated Necrosis | 53 | 4.71e-01 | 0.057200 | 6.91e-01 |
| Negative regulation of MET activity | 20 | 4.74e-01 | -0.092600 | 6.94e-01 |
| RHOC GTPase cycle | 71 | 4.76e-01 | 0.049000 | 6.97e-01 |
| PRC2 methylates histones and DNA | 23 | 4.76e-01 | 0.085800 | 6.97e-01 |
| MAPK family signaling cascades | 288 | 4.79e-01 | -0.024300 | 6.99e-01 |
| Synaptic adhesion-like molecules | 18 | 4.79e-01 | -0.096400 | 6.99e-01 |
| RET signaling | 36 | 4.82e-01 | -0.067800 | 7.02e-01 |
| Signaling by ALK fusions and activated point mutants | 55 | 4.82e-01 | -0.054800 | 7.02e-01 |
| Signaling by ALK in cancer | 55 | 4.82e-01 | -0.054800 | 7.02e-01 |
| Homology Directed Repair | 104 | 4.83e-01 | -0.039800 | 7.02e-01 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | 18 | 4.83e-01 | 0.095500 | 7.02e-01 |
| DARPP-32 events | 23 | 4.85e-01 | -0.084100 | 7.04e-01 |
| Synthesis of very long-chain fatty acyl-CoAs | 24 | 4.86e-01 | 0.082200 | 7.04e-01 |
| RHOBTB1 GTPase cycle | 23 | 4.88e-01 | 0.083500 | 7.07e-01 |
| Signaling by Non-Receptor Tyrosine Kinases | 52 | 4.90e-01 | -0.055300 | 7.08e-01 |
| Signaling by PTK6 | 52 | 4.90e-01 | -0.055300 | 7.08e-01 |
| RHO GTPase cycle | 427 | 4.90e-01 | 0.019500 | 7.08e-01 |
| Postmitotic nuclear pore complex (NPC) reformation | 27 | 4.91e-01 | -0.076600 | 7.08e-01 |
| RAS processing | 19 | 4.91e-01 | -0.091300 | 7.08e-01 |
| Post-chaperonin tubulin folding pathway | 18 | 4.92e-01 | -0.093600 | 7.08e-01 |
| Heme signaling | 44 | 4.93e-01 | 0.059700 | 7.09e-01 |
| Translesion synthesis by POLI | 17 | 4.95e-01 | -0.095500 | 7.12e-01 |
| NF-kB is activated and signals survival | 13 | 4.97e-01 | -0.109000 | 7.13e-01 |
| SUMOylation of DNA damage response and repair proteins | 77 | 4.99e-01 | -0.044500 | 7.16e-01 |
| Synthesis of bile acids and bile salts via 27-hydroxycholesterol | 10 | 5.01e-01 | 0.123000 | 7.17e-01 |
| Transcriptional regulation by RUNX1 | 178 | 5.02e-01 | -0.029200 | 7.17e-01 |
| Synthesis of PE | 12 | 5.02e-01 | -0.112000 | 7.17e-01 |
| TNFs bind their physiological receptors | 24 | 5.02e-01 | -0.079200 | 7.17e-01 |
| Tie2 Signaling | 18 | 5.03e-01 | 0.091100 | 7.18e-01 |
| Acyl chain remodelling of PE | 20 | 5.10e-01 | 0.085100 | 7.27e-01 |
| Regulation of TP53 Expression and Degradation | 36 | 5.12e-01 | -0.063200 | 7.29e-01 |
| Toll Like Receptor 4 (TLR4) Cascade | 127 | 5.13e-01 | -0.033600 | 7.29e-01 |
| RHOG GTPase cycle | 72 | 5.13e-01 | -0.044600 | 7.29e-01 |
| Crosslinking of collagen fibrils | 10 | 5.14e-01 | -0.119000 | 7.30e-01 |
| RHO GTPase Effectors | 243 | 5.15e-01 | -0.024300 | 7.30e-01 |
| Negative regulation of FLT3 | 15 | 5.16e-01 | -0.096900 | 7.30e-01 |
| G alpha (z) signalling events | 40 | 5.16e-01 | 0.059400 | 7.30e-01 |
| G-protein mediated events | 51 | 5.16e-01 | -0.052500 | 7.30e-01 |
| Ovarian tumor domain proteases | 38 | 5.17e-01 | -0.060700 | 7.31e-01 |
| RIP-mediated NFkB activation via ZBP1 | 17 | 5.20e-01 | -0.090100 | 7.34e-01 |
| Unwinding of DNA | 12 | 5.22e-01 | -0.107000 | 7.36e-01 |
| Mitotic Metaphase and Anaphase | 223 | 5.24e-01 | -0.024800 | 7.38e-01 |
| Pre-NOTCH Expression and Processing | 59 | 5.24e-01 | 0.047900 | 7.38e-01 |
| NRAGE signals death through JNK | 58 | 5.28e-01 | 0.048000 | 7.42e-01 |
| Signaling by WNT in cancer | 30 | 5.29e-01 | 0.066500 | 7.43e-01 |
| ATF6 (ATF6-alpha) activates chaperone genes | 10 | 5.32e-01 | -0.114000 | 7.45e-01 |
| Estrogen-dependent gene expression | 97 | 5.33e-01 | 0.036700 | 7.45e-01 |
| ABC transporters in lipid homeostasis | 15 | 5.33e-01 | 0.093000 | 7.45e-01 |
| Caspase-mediated cleavage of cytoskeletal proteins | 12 | 5.34e-01 | -0.104000 | 7.45e-01 |
| NCAM1 interactions | 31 | 5.34e-01 | 0.064500 | 7.45e-01 |
| Syndecan interactions | 20 | 5.34e-01 | -0.080300 | 7.45e-01 |
| TGF-beta receptor signaling activates SMADs | 32 | 5.35e-01 | -0.063400 | 7.45e-01 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | 52 | 5.35e-01 | 0.049800 | 7.45e-01 |
| GABA synthesis, release, reuptake and degradation | 13 | 5.35e-01 | 0.099300 | 7.45e-01 |
| Cell-Cell communication | 98 | 5.36e-01 | 0.036200 | 7.45e-01 |
| Inwardly rectifying K+ channels | 22 | 5.36e-01 | 0.076200 | 7.46e-01 |
| FRS-mediated FGFR1 signaling | 16 | 5.38e-01 | -0.088900 | 7.47e-01 |
| Assembly of the ORC complex at the origin of replication | 19 | 5.41e-01 | 0.081000 | 7.51e-01 |
| Mitotic Anaphase | 222 | 5.42e-01 | -0.023800 | 7.51e-01 |
| Interleukin-37 signaling | 20 | 5.45e-01 | -0.078200 | 7.54e-01 |
| Sensory perception of taste | 20 | 5.45e-01 | 0.078200 | 7.54e-01 |
| Downstream signaling of activated FGFR2 | 23 | 5.49e-01 | 0.072200 | 7.58e-01 |
| RAF activation | 34 | 5.49e-01 | -0.059400 | 7.58e-01 |
| DCC mediated attractive signaling | 13 | 5.51e-01 | 0.095400 | 7.60e-01 |
| CLEC7A (Dectin-1) induces NFAT activation | 11 | 5.52e-01 | 0.104000 | 7.60e-01 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | 28 | 5.52e-01 | 0.064900 | 7.60e-01 |
| RNA Polymerase I Promoter Escape | 41 | 5.54e-01 | -0.053500 | 7.61e-01 |
| RAC2 GTPase cycle | 86 | 5.57e-01 | -0.036600 | 7.65e-01 |
| Regulation of TP53 Activity through Phosphorylation | 89 | 5.58e-01 | 0.035900 | 7.65e-01 |
| Interleukin-27 signaling | 10 | 5.58e-01 | -0.107000 | 7.65e-01 |
| Reproduction | 67 | 5.58e-01 | 0.041400 | 7.65e-01 |
| Signalling to ERKs | 33 | 5.59e-01 | 0.058800 | 7.65e-01 |
| Metalloprotease DUBs | 20 | 5.61e-01 | 0.075100 | 7.66e-01 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | 25 | 5.61e-01 | -0.067200 | 7.66e-01 |
| Presynaptic function of Kainate receptors | 17 | 5.62e-01 | -0.081300 | 7.66e-01 |
| Negative regulators of DDX58/IFIH1 signaling | 35 | 5.62e-01 | -0.056600 | 7.66e-01 |
| IRS-related events triggered by IGF1R | 42 | 5.62e-01 | -0.051700 | 7.66e-01 |
| Amino acid transport across the plasma membrane | 25 | 5.63e-01 | -0.066800 | 7.67e-01 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | 33 | 5.65e-01 | -0.057900 | 7.68e-01 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | 13 | 5.66e-01 | -0.092000 | 7.68e-01 |
| p75 NTR receptor-mediated signalling | 94 | 5.66e-01 | -0.034300 | 7.68e-01 |
| Nephrin family interactions | 20 | 5.67e-01 | -0.074000 | 7.68e-01 |
| CDC42 GTPase cycle | 149 | 5.67e-01 | 0.027200 | 7.68e-01 |
| Processing of Intronless Pre-mRNAs | 19 | 5.68e-01 | -0.075800 | 7.68e-01 |
| Signaling by PDGF | 52 | 5.68e-01 | -0.045800 | 7.68e-01 |
| Listeria monocytogenes entry into host cells | 19 | 5.71e-01 | -0.075200 | 7.71e-01 |
| IRAK1 recruits IKK complex | 10 | 5.75e-01 | 0.102000 | 7.75e-01 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | 10 | 5.75e-01 | 0.102000 | 7.75e-01 |
| TP53 Regulates Transcription of Caspase Activators and Caspases | 12 | 5.76e-01 | 0.093200 | 7.76e-01 |
| PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases | 14 | 5.80e-01 | -0.085500 | 7.80e-01 |
| Interleukin-10 signaling | 37 | 5.80e-01 | 0.052600 | 7.80e-01 |
| Nuclear Envelope (NE) Reassembly | 69 | 5.80e-01 | -0.038500 | 7.80e-01 |
| Interconversion of nucleotide di- and triphosphates | 29 | 5.81e-01 | -0.059200 | 7.80e-01 |
| Transcription of E2F targets under negative control by DREAM complex | 19 | 5.82e-01 | -0.073000 | 7.80e-01 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | 11 | 5.82e-01 | -0.095800 | 7.80e-01 |
| TRAF6 mediated NF-kB activation | 25 | 5.87e-01 | -0.062700 | 7.85e-01 |
| Inflammasomes | 21 | 5.87e-01 | -0.068400 | 7.85e-01 |
| Downstream signaling of activated FGFR4 | 21 | 5.91e-01 | 0.067800 | 7.88e-01 |
| WNT ligand biogenesis and trafficking | 17 | 5.91e-01 | -0.075300 | 7.88e-01 |
| Vitamin B5 (pantothenate) metabolism | 17 | 5.91e-01 | -0.075300 | 7.88e-01 |
| RORA activates gene expression | 18 | 5.92e-01 | -0.073000 | 7.89e-01 |
| Potassium Channels | 63 | 5.94e-01 | 0.038900 | 7.90e-01 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | 17 | 5.95e-01 | -0.074500 | 7.91e-01 |
| DAG and IP3 signaling | 39 | 5.96e-01 | -0.049100 | 7.91e-01 |
| Platelet Aggregation (Plug Formation) | 31 | 5.96e-01 | -0.055000 | 7.91e-01 |
| HSF1-dependent transactivation | 33 | 6.00e-01 | -0.052700 | 7.95e-01 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | 98 | 6.01e-01 | -0.030600 | 7.95e-01 |
| Signaling by ALK | 27 | 6.01e-01 | -0.058200 | 7.95e-01 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | 12 | 6.01e-01 | 0.087200 | 7.95e-01 |
| Sphingolipid de novo biosynthesis | 40 | 6.06e-01 | -0.047200 | 8.00e-01 |
| Cell recruitment (pro-inflammatory response) | 24 | 6.06e-01 | -0.060800 | 8.00e-01 |
| Purinergic signaling in leishmaniasis infection | 24 | 6.06e-01 | -0.060800 | 8.00e-01 |
| Folding of actin by CCT/TriC | 10 | 6.10e-01 | -0.093300 | 8.03e-01 |
| Thrombin signalling through proteinase activated receptors (PARs) | 27 | 6.12e-01 | -0.056400 | 8.06e-01 |
| Oncogene Induced Senescence | 33 | 6.16e-01 | 0.050500 | 8.10e-01 |
| Positive epigenetic regulation of rRNA expression | 56 | 6.17e-01 | -0.038700 | 8.10e-01 |
| Regulation of gene expression by Hypoxia-inducible Factor | 10 | 6.17e-01 | 0.091500 | 8.10e-01 |
| Acyl chain remodelling of PS | 16 | 6.21e-01 | 0.071400 | 8.12e-01 |
| RHO GTPases activate PKNs | 42 | 6.21e-01 | 0.044000 | 8.12e-01 |
| VEGFR2 mediated cell proliferation | 19 | 6.22e-01 | 0.065400 | 8.12e-01 |
| Downstream signaling of activated FGFR3 | 21 | 6.22e-01 | 0.062100 | 8.12e-01 |
| Activation of kainate receptors upon glutamate binding | 24 | 6.23e-01 | -0.058000 | 8.12e-01 |
| Vasopressin regulates renal water homeostasis via Aquaporins | 35 | 6.23e-01 | -0.048000 | 8.12e-01 |
| G beta:gamma signalling through PLC beta | 16 | 6.23e-01 | -0.071000 | 8.12e-01 |
| Rap1 signalling | 14 | 6.24e-01 | -0.075700 | 8.12e-01 |
| G alpha (s) signalling events | 87 | 6.24e-01 | -0.030400 | 8.12e-01 |
| Cilium Assembly | 179 | 6.24e-01 | -0.021200 | 8.12e-01 |
| PI-3K cascade:FGFR1 | 14 | 6.25e-01 | -0.075500 | 8.12e-01 |
| Death Receptor Signalling | 137 | 6.26e-01 | -0.024100 | 8.13e-01 |
| Activated point mutants of FGFR2 | 10 | 6.26e-01 | 0.088900 | 8.13e-01 |
| Reduction of cytosolic Ca++ levels | 10 | 6.33e-01 | 0.087100 | 8.21e-01 |
| Insulin processing | 24 | 6.34e-01 | 0.056100 | 8.21e-01 |
| SUMO E3 ligases SUMOylate target proteins | 162 | 6.35e-01 | -0.021600 | 8.21e-01 |
| rRNA processing in the mitochondrion | 24 | 6.35e-01 | -0.056000 | 8.21e-01 |
| Voltage gated Potassium channels | 25 | 6.37e-01 | 0.054600 | 8.22e-01 |
| Defects in vitamin and cofactor metabolism | 21 | 6.37e-01 | -0.059500 | 8.22e-01 |
| DNA Damage/Telomere Stress Induced Senescence | 38 | 6.38e-01 | -0.044200 | 8.22e-01 |
| RAC3 GTPase cycle | 88 | 6.39e-01 | 0.029000 | 8.23e-01 |
| IGF1R signaling cascade | 43 | 6.40e-01 | -0.041300 | 8.23e-01 |
| Signaling by FGFR4 | 35 | 6.40e-01 | -0.045700 | 8.23e-01 |
| Fertilization | 10 | 6.40e-01 | 0.085400 | 8.23e-01 |
| Caspase activation via extrinsic apoptotic signalling pathway | 23 | 6.43e-01 | -0.055800 | 8.26e-01 |
| G-protein activation | 19 | 6.48e-01 | -0.060500 | 8.31e-01 |
| RHO GTPases activate IQGAPs | 11 | 6.49e-01 | -0.079400 | 8.31e-01 |
| Cyclin D associated events in G1 | 47 | 6.49e-01 | -0.038300 | 8.31e-01 |
| G1 Phase | 47 | 6.49e-01 | -0.038300 | 8.31e-01 |
| Sensory Perception | 153 | 6.57e-01 | -0.020800 | 8.38e-01 |
| Activation of HOX genes during differentiation | 70 | 6.57e-01 | -0.030700 | 8.38e-01 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | 70 | 6.57e-01 | -0.030700 | 8.38e-01 |
| Phosphorylation of the APC/C | 20 | 6.57e-01 | -0.057400 | 8.38e-01 |
| The NLRP3 inflammasome | 16 | 6.59e-01 | -0.063800 | 8.39e-01 |
| Sema4D in semaphorin signaling | 24 | 6.61e-01 | 0.051800 | 8.40e-01 |
| Transcriptional Regulation by VENTX | 39 | 6.61e-01 | 0.040600 | 8.40e-01 |
| Meiosis | 57 | 6.61e-01 | 0.033600 | 8.40e-01 |
| Common Pathway of Fibrin Clot Formation | 12 | 6.62e-01 | 0.072900 | 8.40e-01 |
| activated TAK1 mediates p38 MAPK activation | 19 | 6.62e-01 | 0.057900 | 8.40e-01 |
| RND3 GTPase cycle | 38 | 6.64e-01 | 0.040800 | 8.41e-01 |
| Leading Strand Synthesis | 14 | 6.65e-01 | -0.066900 | 8.41e-01 |
| Polymerase switching | 14 | 6.65e-01 | -0.066900 | 8.41e-01 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | 11 | 6.67e-01 | -0.074900 | 8.43e-01 |
| Telomere C-strand synthesis initiation | 13 | 6.74e-01 | -0.067300 | 8.51e-01 |
| Downstream signal transduction | 29 | 6.75e-01 | -0.045100 | 8.51e-01 |
| Separation of Sister Chromatids | 166 | 6.77e-01 | -0.018700 | 8.54e-01 |
| Termination of O-glycan biosynthesis | 14 | 6.78e-01 | -0.064100 | 8.54e-01 |
| Bile acid and bile salt metabolism | 30 | 6.79e-01 | 0.043700 | 8.54e-01 |
| Endogenous sterols | 22 | 6.80e-01 | -0.050900 | 8.54e-01 |
| Eicosanoid ligand-binding receptors | 14 | 6.81e-01 | -0.063400 | 8.56e-01 |
| p75NTR signals via NF-kB | 16 | 6.83e-01 | -0.059000 | 8.56e-01 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | 22 | 6.83e-01 | -0.050300 | 8.56e-01 |
| Ion homeostasis | 43 | 6.83e-01 | 0.035900 | 8.56e-01 |
| Uptake and function of anthrax toxins | 11 | 6.86e-01 | -0.070400 | 8.59e-01 |
| Lysine catabolism | 12 | 6.89e-01 | 0.066600 | 8.61e-01 |
| Regulation of TP53 Activity through Association with Co-factors | 12 | 6.89e-01 | -0.066600 | 8.61e-01 |
| Biosynthesis of specialized proresolving mediators (SPMs) | 15 | 6.89e-01 | -0.059600 | 8.61e-01 |
| SHC-mediated cascade:FGFR2 | 16 | 6.92e-01 | 0.057200 | 8.64e-01 |
| Biosynthesis of DHA-derived SPMs | 13 | 6.93e-01 | -0.063300 | 8.64e-01 |
| IKK complex recruitment mediated by RIP1 | 23 | 6.95e-01 | -0.047300 | 8.65e-01 |
| N-glycan antennae elongation in the medial/trans-Golgi | 21 | 6.95e-01 | -0.049400 | 8.65e-01 |
| VEGFR2 mediated vascular permeability | 27 | 6.97e-01 | -0.043300 | 8.66e-01 |
| Metabolism of nitric oxide: NOS3 activation and regulation | 15 | 6.97e-01 | 0.058000 | 8.66e-01 |
| Metabolism of cofactors | 19 | 6.99e-01 | -0.051200 | 8.68e-01 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | 46 | 7.00e-01 | 0.032900 | 8.68e-01 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | 19 | 7.03e-01 | -0.050500 | 8.70e-01 |
| Signaling by FGFR3 in disease | 18 | 7.03e-01 | 0.051900 | 8.70e-01 |
| Signaling by FGFR3 point mutants in cancer | 18 | 7.03e-01 | 0.051900 | 8.70e-01 |
| Signaling by FGFR1 in disease | 33 | 7.05e-01 | 0.038100 | 8.71e-01 |
| PI Metabolism | 80 | 7.10e-01 | -0.024100 | 8.74e-01 |
| Regulation of BACH1 activity | 11 | 7.10e-01 | -0.064700 | 8.74e-01 |
| Blood group systems biosynthesis | 16 | 7.14e-01 | -0.052900 | 8.74e-01 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | 10 | 7.14e-01 | 0.066900 | 8.74e-01 |
| S33 mutants of beta-catenin aren’t phosphorylated | 15 | 7.15e-01 | 0.054500 | 8.74e-01 |
| S37 mutants of beta-catenin aren’t phosphorylated | 15 | 7.15e-01 | 0.054500 | 8.74e-01 |
| S45 mutants of beta-catenin aren’t phosphorylated | 15 | 7.15e-01 | 0.054500 | 8.74e-01 |
| Signaling by CTNNB1 phospho-site mutants | 15 | 7.15e-01 | 0.054500 | 8.74e-01 |
| Signaling by GSK3beta mutants | 15 | 7.15e-01 | 0.054500 | 8.74e-01 |
| T41 mutants of beta-catenin aren’t phosphorylated | 15 | 7.15e-01 | 0.054500 | 8.74e-01 |
| SHC-mediated cascade:FGFR1 | 14 | 7.15e-01 | -0.056300 | 8.74e-01 |
| MAP kinase activation | 63 | 7.16e-01 | 0.026500 | 8.74e-01 |
| RHOA GTPase cycle | 145 | 7.16e-01 | -0.017500 | 8.74e-01 |
| Nicotinamide salvaging | 16 | 7.16e-01 | 0.052500 | 8.74e-01 |
| Formation of Fibrin Clot (Clotting Cascade) | 24 | 7.16e-01 | -0.042800 | 8.74e-01 |
| SUMOylation of transcription factors | 17 | 7.17e-01 | -0.050900 | 8.74e-01 |
| Amine ligand-binding receptors | 16 | 7.18e-01 | 0.052100 | 8.75e-01 |
| ADORA2B mediated anti-inflammatory cytokines production | 75 | 7.19e-01 | -0.024100 | 8.75e-01 |
| Collagen degradation | 34 | 7.20e-01 | -0.035500 | 8.76e-01 |
| Meiotic synapsis | 37 | 7.21e-01 | 0.033900 | 8.76e-01 |
| Signaling by ERBB2 KD Mutants | 24 | 7.22e-01 | 0.041900 | 8.77e-01 |
| Cell death signalling via NRAGE, NRIF and NADE | 75 | 7.24e-01 | -0.023600 | 8.78e-01 |
| Antiviral mechanism by IFN-stimulated genes | 80 | 7.29e-01 | 0.022400 | 8.83e-01 |
| Negative regulation of MAPK pathway | 42 | 7.30e-01 | -0.030800 | 8.83e-01 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | 11 | 7.30e-01 | -0.060000 | 8.83e-01 |
| Signaling by MET | 65 | 7.31e-01 | -0.024700 | 8.83e-01 |
| G0 and Early G1 | 26 | 7.31e-01 | 0.038900 | 8.83e-01 |
| Extra-nuclear estrogen signaling | 67 | 7.32e-01 | -0.024200 | 8.83e-01 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | 13 | 7.32e-01 | -0.054800 | 8.83e-01 |
| PKA activation | 17 | 7.33e-01 | -0.047800 | 8.83e-01 |
| Prolonged ERK activation events | 14 | 7.34e-01 | -0.052500 | 8.83e-01 |
| Signaling by cytosolic FGFR1 fusion mutants | 18 | 7.34e-01 | 0.046200 | 8.83e-01 |
| Peptide hormone metabolism | 62 | 7.37e-01 | -0.024700 | 8.85e-01 |
| Acetylcholine regulates insulin secretion | 10 | 7.37e-01 | -0.061200 | 8.85e-01 |
| Signaling by FGFR3 | 36 | 7.37e-01 | -0.032300 | 8.85e-01 |
| TP53 Regulates Transcription of Cell Cycle Genes | 45 | 7.38e-01 | -0.028800 | 8.85e-01 |
| Insulin receptor signalling cascade | 44 | 7.43e-01 | -0.028600 | 8.90e-01 |
| Signaling by NTRK2 (TRKB) | 23 | 7.47e-01 | -0.038900 | 8.92e-01 |
| Intraflagellar transport | 39 | 7.48e-01 | -0.029800 | 8.92e-01 |
| FOXO-mediated transcription of cell death genes | 15 | 7.49e-01 | 0.047700 | 8.92e-01 |
| Senescence-Associated Secretory Phenotype (SASP) | 60 | 7.50e-01 | -0.023800 | 8.92e-01 |
| tRNA processing in the mitochondrion | 26 | 7.51e-01 | -0.036000 | 8.92e-01 |
| Defective pyroptosis | 23 | 7.53e-01 | 0.037900 | 8.92e-01 |
| SHC-mediated cascade:FGFR4 | 14 | 7.53e-01 | 0.048500 | 8.92e-01 |
| RHOJ GTPase cycle | 54 | 7.54e-01 | 0.024700 | 8.92e-01 |
| HDR through Homologous Recombination (HRR) | 66 | 7.54e-01 | -0.022300 | 8.92e-01 |
| HDR through Single Strand Annealing (SSA) | 37 | 7.55e-01 | 0.029700 | 8.92e-01 |
| Inositol phosphate metabolism | 45 | 7.55e-01 | 0.026900 | 8.92e-01 |
| Synthesis of IP3 and IP4 in the cytosol | 24 | 7.55e-01 | -0.036800 | 8.92e-01 |
| Meiotic recombination | 30 | 7.55e-01 | -0.032900 | 8.92e-01 |
| TICAM1, RIP1-mediated IKK complex recruitment | 19 | 7.57e-01 | 0.041100 | 8.92e-01 |
| Synthesis of PIPs at the plasma membrane | 52 | 7.57e-01 | 0.024800 | 8.92e-01 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | 97 | 7.57e-01 | -0.018200 | 8.92e-01 |
| Toll Like Receptor 2 (TLR2) Cascade | 97 | 7.57e-01 | -0.018200 | 8.92e-01 |
| Toll Like Receptor TLR1:TLR2 Cascade | 97 | 7.57e-01 | -0.018200 | 8.92e-01 |
| Toll Like Receptor TLR6:TLR2 Cascade | 97 | 7.57e-01 | -0.018200 | 8.92e-01 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | 34 | 7.58e-01 | -0.030600 | 8.92e-01 |
| Degradation of the extracellular matrix | 94 | 7.58e-01 | 0.018400 | 8.92e-01 |
| Interferon Signaling | 178 | 7.58e-01 | 0.013400 | 8.93e-01 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | 16 | 7.59e-01 | -0.044300 | 8.93e-01 |
| Platelet homeostasis | 75 | 7.62e-01 | 0.020200 | 8.95e-01 |
| SUMOylation | 168 | 7.64e-01 | -0.013400 | 8.96e-01 |
| Signaling by Erythropoietin | 24 | 7.65e-01 | -0.035300 | 8.96e-01 |
| SHC1 events in ERBB4 signaling | 13 | 7.65e-01 | 0.047800 | 8.96e-01 |
| CaMK IV-mediated phosphorylation of CREB | 10 | 7.66e-01 | 0.054300 | 8.96e-01 |
| Downstream signaling of activated FGFR1 | 23 | 7.66e-01 | 0.035800 | 8.96e-01 |
| Signaling by ERBB2 in Cancer | 25 | 7.66e-01 | 0.034300 | 8.96e-01 |
| Platelet calcium homeostasis | 23 | 7.68e-01 | -0.035600 | 8.97e-01 |
| Deactivation of the beta-catenin transactivating complex | 39 | 7.70e-01 | 0.027100 | 8.97e-01 |
| Integrin cell surface interactions | 60 | 7.70e-01 | 0.021800 | 8.97e-01 |
| Constitutive Signaling by EGFRvIII | 15 | 7.71e-01 | 0.043400 | 8.97e-01 |
| Signaling by EGFRvIII in Cancer | 15 | 7.71e-01 | 0.043400 | 8.97e-01 |
| G alpha (i) signalling events | 207 | 7.72e-01 | 0.011700 | 8.97e-01 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | 17 | 7.72e-01 | 0.040600 | 8.97e-01 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | 17 | 7.72e-01 | 0.040600 | 8.97e-01 |
| Interferon gamma signaling | 84 | 7.75e-01 | -0.018000 | 8.99e-01 |
| Alpha-protein kinase 1 signaling pathway | 11 | 7.76e-01 | -0.049600 | 8.99e-01 |
| Erythrocytes take up carbon dioxide and release oxygen | 11 | 7.76e-01 | 0.049500 | 8.99e-01 |
| O2/CO2 exchange in erythrocytes | 11 | 7.76e-01 | 0.049500 | 8.99e-01 |
| PI-3K cascade:FGFR2 | 16 | 7.80e-01 | 0.040300 | 9.01e-01 |
| Caspase activation via Death Receptors in the presence of ligand | 15 | 7.82e-01 | 0.041400 | 9.01e-01 |
| Condensation of Prometaphase Chromosomes | 11 | 7.82e-01 | 0.048100 | 9.01e-01 |
| MASTL Facilitates Mitotic Progression | 10 | 7.82e-01 | -0.050500 | 9.01e-01 |
| TRAF3-dependent IRF activation pathway | 14 | 7.82e-01 | -0.042600 | 9.01e-01 |
| N-Glycan antennae elongation | 13 | 7.83e-01 | 0.044100 | 9.01e-01 |
| DNA methylation | 14 | 7.84e-01 | 0.042400 | 9.01e-01 |
| IL-6-type cytokine receptor ligand interactions | 15 | 7.85e-01 | 0.040800 | 9.01e-01 |
| Intrinsic Pathway of Fibrin Clot Formation | 14 | 7.85e-01 | -0.042200 | 9.01e-01 |
| Interleukin-7 signaling | 21 | 7.85e-01 | 0.034400 | 9.01e-01 |
| Surfactant metabolism | 21 | 7.85e-01 | 0.034400 | 9.01e-01 |
| Activated NTRK2 signals through FRS2 and FRS3 | 10 | 7.85e-01 | 0.049800 | 9.01e-01 |
| Negative regulation of TCF-dependent signaling by WNT ligand antagonists | 11 | 7.87e-01 | -0.047100 | 9.02e-01 |
| eNOS activation | 11 | 7.90e-01 | 0.046500 | 9.04e-01 |
| Regulation of TP53 Activity through Methylation | 19 | 7.92e-01 | 0.034900 | 9.06e-01 |
| ADP signalling through P2Y purinoceptor 12 | 17 | 7.93e-01 | -0.036800 | 9.06e-01 |
| Tryptophan catabolism | 12 | 7.95e-01 | -0.043200 | 9.08e-01 |
| SHC-mediated cascade:FGFR3 | 14 | 7.96e-01 | 0.040000 | 9.08e-01 |
| MET activates RAP1 and RAC1 | 11 | 7.96e-01 | 0.045000 | 9.08e-01 |
| Anchoring of the basal body to the plasma membrane | 96 | 7.97e-01 | 0.015200 | 9.09e-01 |
| Regulation of IFNG signaling | 13 | 7.98e-01 | 0.041100 | 9.09e-01 |
| Formation of tubulin folding intermediates by CCT/TriC | 21 | 8.03e-01 | -0.031500 | 9.14e-01 |
| RNA Polymerase II Transcription Termination | 65 | 8.05e-01 | -0.017700 | 9.14e-01 |
| Non-integrin membrane-ECM interactions | 41 | 8.05e-01 | 0.022200 | 9.14e-01 |
| Cellular hexose transport | 15 | 8.06e-01 | -0.036700 | 9.14e-01 |
| HDR through MMEJ (alt-NHEJ) | 10 | 8.06e-01 | -0.044900 | 9.14e-01 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | 36 | 8.07e-01 | 0.023500 | 9.15e-01 |
| Activation of RAC1 | 11 | 8.09e-01 | -0.042200 | 9.16e-01 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | 26 | 8.15e-01 | 0.026500 | 9.23e-01 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | 11 | 8.16e-01 | -0.040600 | 9.23e-01 |
| Sialic acid metabolism | 29 | 8.18e-01 | -0.024700 | 9.24e-01 |
| AURKA Activation by TPX2 | 71 | 8.18e-01 | 0.015800 | 9.24e-01 |
| STAT5 activation downstream of FLT3 ITD mutants | 10 | 8.20e-01 | 0.041600 | 9.25e-01 |
| Synthesis of PA | 32 | 8.20e-01 | 0.023200 | 9.25e-01 |
| RHOF GTPase cycle | 40 | 8.21e-01 | -0.020600 | 9.25e-01 |
| Nuclear Receptor transcription pathway | 41 | 8.22e-01 | -0.020300 | 9.25e-01 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | 13 | 8.24e-01 | -0.035500 | 9.27e-01 |
| Signaling by FGFR3 fusions in cancer | 10 | 8.25e-01 | -0.040400 | 9.27e-01 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | 19 | 8.27e-01 | -0.029000 | 9.27e-01 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | 19 | 8.27e-01 | -0.029000 | 9.27e-01 |
| Signaling by FGFR4 in disease | 10 | 8.27e-01 | 0.039900 | 9.27e-01 |
| Free fatty acids regulate insulin secretion | 10 | 8.28e-01 | 0.039600 | 9.27e-01 |
| Signaling by ERBB2 TMD/JMD mutants | 21 | 8.28e-01 | 0.027300 | 9.27e-01 |
| ZBP1(DAI) mediated induction of type I IFNs | 20 | 8.31e-01 | -0.027600 | 9.29e-01 |
| Activation of Matrix Metalloproteinases | 26 | 8.32e-01 | 0.024000 | 9.30e-01 |
| Class B/2 (Secretin family receptors) | 60 | 8.34e-01 | -0.015600 | 9.31e-01 |
| Platelet Adhesion to exposed collagen | 10 | 8.34e-01 | -0.038200 | 9.31e-01 |
| p75NTR recruits signalling complexes | 13 | 8.35e-01 | -0.033400 | 9.31e-01 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | 16 | 8.36e-01 | -0.029900 | 9.31e-01 |
| Signaling by CSF3 (G-CSF) | 30 | 8.36e-01 | -0.021800 | 9.31e-01 |
| STAT3 nuclear events downstream of ALK signaling | 10 | 8.38e-01 | 0.037200 | 9.33e-01 |
| Constitutive Signaling by Overexpressed ERBB2 | 11 | 8.39e-01 | 0.035400 | 9.33e-01 |
| Regulation of PTEN gene transcription | 60 | 8.42e-01 | 0.014900 | 9.34e-01 |
| RNA Polymerase I Promoter Clearance | 60 | 8.43e-01 | -0.014800 | 9.34e-01 |
| RNA Polymerase I Transcription | 60 | 8.43e-01 | -0.014800 | 9.34e-01 |
| Apoptotic factor-mediated response | 20 | 8.44e-01 | -0.025400 | 9.34e-01 |
| TRAF6 mediated IRF7 activation | 16 | 8.44e-01 | -0.028400 | 9.34e-01 |
| Fatty acyl-CoA biosynthesis | 36 | 8.45e-01 | -0.018900 | 9.34e-01 |
| Attenuation phase | 23 | 8.45e-01 | -0.023600 | 9.34e-01 |
| MET receptor recycling | 10 | 8.47e-01 | 0.035300 | 9.36e-01 |
| PI-3K cascade:FGFR4 | 14 | 8.50e-01 | 0.029200 | 9.38e-01 |
| FGFR2 ligand binding and activation | 12 | 8.50e-01 | -0.031600 | 9.38e-01 |
| G1/S-Specific Transcription | 28 | 8.54e-01 | 0.020100 | 9.41e-01 |
| SUMOylation of transcription cofactors | 44 | 8.55e-01 | -0.016000 | 9.41e-01 |
| Activation of G protein gated Potassium channels | 19 | 8.56e-01 | -0.024100 | 9.41e-01 |
| G protein gated Potassium channels | 19 | 8.56e-01 | -0.024100 | 9.41e-01 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | 19 | 8.56e-01 | -0.024100 | 9.41e-01 |
| Regulation of FZD by ubiquitination | 18 | 8.57e-01 | -0.024500 | 9.42e-01 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | 27 | 8.60e-01 | -0.019700 | 9.43e-01 |
| Signaling by BRAF and RAF1 fusions | 59 | 8.60e-01 | 0.013200 | 9.44e-01 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | 33 | 8.62e-01 | 0.017500 | 9.44e-01 |
| Lysosphingolipid and LPA receptors | 10 | 8.65e-01 | -0.031100 | 9.47e-01 |
| FGFR1 mutant receptor activation | 26 | 8.66e-01 | -0.019200 | 9.47e-01 |
| Cobalamin (Cbl, vitamin B12) transport and metabolism | 15 | 8.67e-01 | 0.024900 | 9.48e-01 |
| Acyl chain remodelling of PG | 12 | 8.71e-01 | 0.027100 | 9.51e-01 |
| MyD88-independent TLR4 cascade | 97 | 8.73e-01 | -0.009370 | 9.52e-01 |
| TRIF(TICAM1)-mediated TLR4 signaling | 97 | 8.73e-01 | -0.009370 | 9.52e-01 |
| Integration of energy metabolism | 93 | 8.74e-01 | 0.009540 | 9.52e-01 |
| Downregulation of TGF-beta receptor signaling | 26 | 8.74e-01 | -0.017900 | 9.52e-01 |
| RHOD GTPase cycle | 51 | 8.76e-01 | -0.012700 | 9.53e-01 |
| p38MAPK events | 13 | 8.77e-01 | 0.024800 | 9.54e-01 |
| Signaling by TGF-beta Receptor Complex | 75 | 8.78e-01 | -0.010300 | 9.54e-01 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | 36 | 8.80e-01 | -0.014600 | 9.54e-01 |
| G2/M DNA damage checkpoint | 62 | 8.80e-01 | 0.011100 | 9.54e-01 |
| SIRT1 negatively regulates rRNA expression | 18 | 8.80e-01 | 0.020500 | 9.54e-01 |
| VxPx cargo-targeting to cilium | 18 | 8.80e-01 | 0.020500 | 9.54e-01 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | 91 | 8.82e-01 | -0.009000 | 9.55e-01 |
| Beta-catenin phosphorylation cascade | 17 | 8.86e-01 | 0.020100 | 9.56e-01 |
| HDACs deacetylate histones | 39 | 8.87e-01 | -0.013200 | 9.56e-01 |
| Processing of DNA double-strand break ends | 65 | 8.88e-01 | -0.010100 | 9.56e-01 |
| Adenylate cyclase inhibitory pathway | 13 | 8.88e-01 | 0.022500 | 9.56e-01 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | 89 | 8.89e-01 | -0.008590 | 9.56e-01 |
| Interleukin-15 signaling | 14 | 8.89e-01 | -0.021500 | 9.56e-01 |
| Processing and activation of SUMO | 10 | 8.90e-01 | -0.025200 | 9.56e-01 |
| Chromatin modifying enzymes | 210 | 8.92e-01 | 0.005430 | 9.56e-01 |
| Chromatin organization | 210 | 8.92e-01 | 0.005430 | 9.56e-01 |
| ISG15 antiviral mechanism | 72 | 8.93e-01 | -0.009190 | 9.56e-01 |
| PI-3K cascade:FGFR3 | 14 | 8.93e-01 | 0.020700 | 9.56e-01 |
| Deadenylation of mRNA | 22 | 8.95e-01 | -0.016300 | 9.56e-01 |
| Diseases of mitotic cell cycle | 38 | 8.96e-01 | 0.012200 | 9.56e-01 |
| Signaling by PDGFR in disease | 20 | 8.96e-01 | -0.016800 | 9.56e-01 |
| Activation of the pre-replicative complex | 31 | 8.97e-01 | 0.013500 | 9.56e-01 |
| Carboxyterminal post-translational modifications of tubulin | 29 | 8.98e-01 | 0.013800 | 9.56e-01 |
| APC truncation mutants have impaired AXIN binding | 14 | 8.99e-01 | 0.019500 | 9.56e-01 |
| AXIN missense mutants destabilize the destruction complex | 14 | 8.99e-01 | 0.019500 | 9.56e-01 |
| Signaling by AMER1 mutants | 14 | 8.99e-01 | 0.019500 | 9.56e-01 |
| Signaling by APC mutants | 14 | 8.99e-01 | 0.019500 | 9.56e-01 |
| Signaling by AXIN mutants | 14 | 8.99e-01 | 0.019500 | 9.56e-01 |
| Truncations of AMER1 destabilize the destruction complex | 14 | 8.99e-01 | 0.019500 | 9.56e-01 |
| MyD88 cascade initiated on plasma membrane | 83 | 9.00e-01 | 0.007990 | 9.56e-01 |
| Toll Like Receptor 10 (TLR10) Cascade | 83 | 9.00e-01 | 0.007990 | 9.56e-01 |
| Toll Like Receptor 5 (TLR5) Cascade | 83 | 9.00e-01 | 0.007990 | 9.56e-01 |
| G alpha (12/13) signalling events | 74 | 9.00e-01 | -0.008460 | 9.56e-01 |
| PKA-mediated phosphorylation of CREB | 19 | 9.02e-01 | -0.016300 | 9.57e-01 |
| Signaling by FLT3 ITD and TKD mutants | 16 | 9.02e-01 | 0.017800 | 9.57e-01 |
| Maturation of nucleoprotein | 11 | 9.06e-01 | -0.020600 | 9.60e-01 |
| Ion transport by P-type ATPases | 43 | 9.06e-01 | 0.010400 | 9.60e-01 |
| FRS-mediated FGFR2 signaling | 18 | 9.09e-01 | 0.015600 | 9.62e-01 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | 20 | 9.11e-01 | 0.014500 | 9.62e-01 |
| Negative epigenetic regulation of rRNA expression | 59 | 9.11e-01 | -0.008440 | 9.62e-01 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | 51 | 9.11e-01 | 0.009010 | 9.62e-01 |
| MyD88 dependent cascade initiated on endosome | 90 | 9.13e-01 | -0.006700 | 9.63e-01 |
| IRAK2 mediated activation of TAK1 complex | 10 | 9.14e-01 | 0.019800 | 9.64e-01 |
| Cytochrome P450 - arranged by substrate type | 38 | 9.18e-01 | 0.009680 | 9.66e-01 |
| RND1 GTPase cycle | 40 | 9.18e-01 | 0.009420 | 9.66e-01 |
| Protein-protein interactions at synapses | 71 | 9.20e-01 | -0.006930 | 9.68e-01 |
| Activated NOTCH1 Transmits Signal to the Nucleus | 29 | 9.21e-01 | 0.010600 | 9.69e-01 |
| Inactivation of CSF3 (G-CSF) signaling | 25 | 9.22e-01 | -0.011300 | 9.69e-01 |
| Regulation of PLK1 Activity at G2/M Transition | 86 | 9.23e-01 | -0.006000 | 9.69e-01 |
| Polo-like kinase mediated events | 15 | 9.24e-01 | -0.014200 | 9.70e-01 |
| Interleukin-20 family signaling | 16 | 9.25e-01 | 0.013600 | 9.70e-01 |
| NoRC negatively regulates rRNA expression | 56 | 9.26e-01 | -0.007220 | 9.70e-01 |
| STING mediated induction of host immune responses | 15 | 9.27e-01 | -0.013700 | 9.70e-01 |
| Defects in cobalamin (B12) metabolism | 13 | 9.28e-01 | -0.014600 | 9.70e-01 |
| Signaling by NOTCH2 | 32 | 9.29e-01 | -0.009080 | 9.71e-01 |
| Acyl chain remodelling of PI | 11 | 9.30e-01 | -0.015400 | 9.71e-01 |
| Cell Cycle Checkpoints | 250 | 9.33e-01 | -0.003100 | 9.72e-01 |
| Pre-NOTCH Processing in Golgi | 18 | 9.33e-01 | 0.011400 | 9.72e-01 |
| Loss of Nlp from mitotic centrosomes | 68 | 9.34e-01 | 0.005790 | 9.72e-01 |
| Loss of proteins required for interphase microtubule organization from the centrosome | 68 | 9.34e-01 | 0.005790 | 9.72e-01 |
| Toll Like Receptor 9 (TLR9) Cascade | 94 | 9.34e-01 | -0.004910 | 9.72e-01 |
| Chemokine receptors bind chemokines | 42 | 9.35e-01 | 0.007330 | 9.72e-01 |
| Interleukin-17 signaling | 67 | 9.38e-01 | 0.005540 | 9.74e-01 |
| Signaling by ERBB2 ECD mutants | 16 | 9.38e-01 | 0.011200 | 9.75e-01 |
| SUMOylation of intracellular receptors | 27 | 9.39e-01 | 0.008500 | 9.75e-01 |
| Assembly of collagen fibrils and other multimeric structures | 54 | 9.40e-01 | 0.005900 | 9.75e-01 |
| Nicotinate metabolism | 27 | 9.43e-01 | -0.007970 | 9.77e-01 |
| Ephrin signaling | 19 | 9.43e-01 | 0.009490 | 9.77e-01 |
| MET activates RAS signaling | 11 | 9.45e-01 | 0.012100 | 9.77e-01 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | 17 | 9.45e-01 | 0.009640 | 9.77e-01 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | 21 | 9.46e-01 | 0.008600 | 9.77e-01 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | 21 | 9.46e-01 | 0.008600 | 9.77e-01 |
| Oncogenic MAPK signaling | 75 | 9.49e-01 | -0.004300 | 9.79e-01 |
| ERK/MAPK targets | 22 | 9.52e-01 | 0.007370 | 9.82e-01 |
| Sensory perception of sweet, bitter, and umami (glutamate) taste | 16 | 9.54e-01 | 0.008290 | 9.82e-01 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | 19 | 9.56e-01 | -0.007250 | 9.82e-01 |
| Condensation of Prophase Chromosomes | 23 | 9.57e-01 | -0.006510 | 9.82e-01 |
| Acyl chain remodelling of PC | 20 | 9.57e-01 | -0.006920 | 9.82e-01 |
| APC-Cdc20 mediated degradation of Nek2A | 26 | 9.58e-01 | -0.006040 | 9.82e-01 |
| Protein methylation | 15 | 9.58e-01 | -0.007860 | 9.82e-01 |
| Stimuli-sensing channels | 75 | 9.59e-01 | -0.003420 | 9.82e-01 |
| mRNA 3’-end processing | 56 | 9.60e-01 | 0.003920 | 9.82e-01 |
| Activation of GABAB receptors | 32 | 9.60e-01 | -0.005180 | 9.82e-01 |
| GABA B receptor activation | 32 | 9.60e-01 | -0.005180 | 9.82e-01 |
| NOTCH2 intracellular domain regulates transcription | 11 | 9.60e-01 | 0.008760 | 9.82e-01 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | 12 | 9.60e-01 | 0.008340 | 9.82e-01 |
| GABA receptor activation | 40 | 9.62e-01 | -0.004390 | 9.83e-01 |
| PERK regulates gene expression | 32 | 9.63e-01 | 0.004740 | 9.83e-01 |
| ESR-mediated signaling | 160 | 9.64e-01 | 0.002100 | 9.83e-01 |
| Nucleotide catabolism | 27 | 9.64e-01 | -0.004950 | 9.83e-01 |
| IRF3-mediated induction of type I IFN | 12 | 9.65e-01 | -0.007380 | 9.83e-01 |
| RNA Polymerase I Transcription Initiation | 47 | 9.66e-01 | -0.003550 | 9.84e-01 |
| NCAM signaling for neurite out-growth | 52 | 9.68e-01 | 0.003190 | 9.85e-01 |
| Regulation of TP53 Activity | 154 | 9.72e-01 | 0.001650 | 9.88e-01 |
| ATF4 activates genes in response to endoplasmic reticulum stress | 27 | 9.72e-01 | 0.003880 | 9.88e-01 |
| FRS-mediated FGFR3 signaling | 16 | 9.74e-01 | -0.004670 | 9.88e-01 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | 20 | 9.74e-01 | -0.004160 | 9.88e-01 |
| Keratan sulfate biosynthesis | 28 | 9.76e-01 | -0.003320 | 9.88e-01 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | 26 | 9.77e-01 | 0.003330 | 9.88e-01 |
| Trafficking of AMPA receptors | 26 | 9.77e-01 | 0.003330 | 9.88e-01 |
| Toll Like Receptor 3 (TLR3) Cascade | 93 | 9.77e-01 | 0.001710 | 9.88e-01 |
| Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol | 16 | 9.78e-01 | -0.004040 | 9.88e-01 |
| Growth hormone receptor signaling | 20 | 9.78e-01 | 0.003560 | 9.88e-01 |
| Aquaporin-mediated transport | 38 | 9.78e-01 | -0.002580 | 9.88e-01 |
| Regulation of IFNA signaling | 12 | 9.80e-01 | 0.004120 | 9.89e-01 |
| Adenylate cyclase activating pathway | 10 | 9.81e-01 | 0.004350 | 9.89e-01 |
| Recruitment of NuMA to mitotic centrosomes | 79 | 9.81e-01 | 0.001530 | 9.89e-01 |
| FRS-mediated FGFR4 signaling | 16 | 9.85e-01 | 0.002790 | 9.91e-01 |
| Depolymerisation of the Nuclear Lamina | 15 | 9.86e-01 | 0.002530 | 9.93e-01 |
| Basigin interactions | 24 | 9.90e-01 | -0.001450 | 9.95e-01 |
| FLT3 signaling in disease | 28 | 9.91e-01 | 0.001220 | 9.95e-01 |
| EPHA-mediated growth cone collapse | 15 | 9.91e-01 | -0.001620 | 9.95e-01 |
| Formation of the beta-catenin:TCF transactivating complex | 40 | 9.92e-01 | -0.000959 | 9.95e-01 |
| P2Y receptors | 11 | 9.92e-01 | -0.001680 | 9.95e-01 |
| HuR (ELAVL1) binds and stabilizes mRNA | 10 | 9.94e-01 | -0.001400 | 9.95e-01 |
| Centrosome maturation | 80 | 9.94e-01 | 0.000459 | 9.95e-01 |
| Recruitment of mitotic centrosome proteins and complexes | 80 | 9.94e-01 | 0.000459 | 9.95e-01 |
| TAK1 activates NFkB by phosphorylation and activation of IKKs complex | 28 | 9.96e-01 | -0.000485 | 9.96e-01 |
Detailed Gene set reports
Metabolism
| 664 | |
|---|---|
| set | Metabolism |
| setSize | 1829 |
| pANOVA | 9.99e-42 |
| s.dist | -0.192 |
| p.adjustANOVA | 1.45e-38 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| CBS | -9158 |
| CBR1 | -9134 |
| TSTD1 | -9111 |
| CES1 | -9105 |
| MFSD2A | -9089 |
| COMT | -9062 |
| SERINC2 | -9058 |
| ABCC2 | -9053 |
| LRP1 | -9029 |
| CYB5R3 | -9018 |
| GSTM1 | -9003 |
| ALDH2 | -8976 |
| PLPP3 | -8969 |
| RPS26 | -8966 |
| ABCD1 | -8964 |
| FBP1 | -8962 |
| PSPH | -8960 |
| CPTP | -8943 |
| CD38 | -8938 |
| GAA | -8936 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CBS | -9158 |
| CBR1 | -9134 |
| TSTD1 | -9111 |
| CES1 | -9105 |
| MFSD2A | -9089 |
| COMT | -9062 |
| SERINC2 | -9058 |
| ABCC2 | -9053 |
| LRP1 | -9029 |
| CYB5R3 | -9018 |
| GSTM1 | -9003 |
| ALDH2 | -8976 |
| PLPP3 | -8969 |
| RPS26 | -8966 |
| ABCD1 | -8964 |
| FBP1 | -8962 |
| PSPH | -8960 |
| CPTP | -8943 |
| CD38 | -8938 |
| GAA | -8936 |
| SLC52A2 | -8925 |
| TMEM86B | -8921 |
| TSPO | -8915 |
| CHPF2 | -8912 |
| AK1 | -8906 |
| PC | -8891 |
| IP6K3 | -8889 |
| PCYT2 | -8877 |
| CTSA | -8873 |
| CRAT | -8870 |
| FMOD | -8843 |
| ALDH3B1 | -8840 |
| ASS1 | -8829 |
| CA9 | -8825 |
| CHST12 | -8810 |
| ORMDL3 | -8807 |
| PIK3R2 | -8767 |
| CARM1 | -8755 |
| SLC35B2 | -8753 |
| GAPDH | -8745 |
| PLIN3 | -8737 |
| FUT4 | -8736 |
| NUP210 | -8727 |
| TST | -8714 |
| BSG | -8711 |
| MAN2B2 | -8700 |
| HSD17B1 | -8685 |
| ST6GALNAC6 | -8684 |
| KERA | -8680 |
| AACS | -8676 |
| APOB | -8671 |
| CHPF | -8666 |
| ACO2 | -8665 |
| CES3 | -8663 |
| SEC13 | -8653 |
| HK3 | -8652 |
| NQO2 | -8649 |
| PCK2 | -8648 |
| CBR3 | -8643 |
| ALDOA | -8627 |
| NHLRC1 | -8617 |
| SHMT2 | -8605 |
| SLC25A19 | -8587 |
| SLC6A12 | -8576 |
| GNB2 | -8571 |
| B4GAT1 | -8568 |
| VKORC1 | -8565 |
| G6PC3 | -8561 |
| HS6ST1 | -8558 |
| SURF1 | -8554 |
| DHCR24 | -8540 |
| GLUL | -8536 |
| PYCR1 | -8534 |
| MAN2B1 | -8524 |
| GPX4 | -8514 |
| NDUFAF3 | -8511 |
| SDC3 | -8509 |
| NDUFA11 | -8504 |
| PRKACA | -8490 |
| NMRAL1 | -8476 |
| OSBPL5 | -8468 |
| GBA | -8462 |
| NCOR2 | -8458 |
| AKT1 | -8448 |
| ATIC | -8444 |
| LHPP | -8439 |
| NDST2 | -8423 |
| MED18 | -8417 |
| HYAL1 | -8407 |
| ITPK1 | -8401 |
| ELOVL3 | -8399 |
| GCHFR | -8390 |
| FABP3 | -8382 |
| CEMIP | -8376 |
| SLC37A2 | -8373 |
| NNMT | -8371 |
| SMPD1 | -8363 |
| CYC1 | -8353 |
| HS3ST2 | -8351 |
| TNFAIP8L2 | -8338 |
| PSMD3 | -8328 |
| GALK1 | -8324 |
| B4GALT2 | -8317 |
| PLD3 | -8311 |
| TECR | -8301 |
| ARF3 | -8293 |
| UCK1 | -8291 |
| MDH2 | -8286 |
| ORMDL2 | -8285 |
| PODXL2 | -8274 |
| UROD | -8266 |
| LRP10 | -8262 |
| COX8A | -8260 |
| PPP1CA | -8257 |
| SLC25A11 | -8254 |
| OGDH | -8244 |
| DGUOK | -8238 |
| TACO1 | -8234 |
| ATP5MF | -8232 |
| UST | -8230 |
| PNPLA6 | -8221 |
| FLAD1 | -8220 |
| SULT1A1 | -8219 |
| PFKP | -8214 |
| ATP5F1D | -8212 |
| CERS2 | -8207 |
| BCKDHA | -8203 |
| COASY | -8197 |
| SLC9A1 | -8195 |
| CHST2 | -8190 |
| GLB1 | -8189 |
| CERS4 | -8179 |
| G6PD | -8168 |
| MED9 | -8162 |
| ALDH18A1 | -8160 |
| ETFB | -8156 |
| PLCH2 | -8151 |
| PSMD8 | -8149 |
| NUBP2 | -8140 |
| SARDH | -8137 |
| APRT | -8130 |
| NUDT18 | -8114 |
| HPGDS | -8112 |
| PEX11A | -8103 |
| GLUD2 | -8102 |
| MED19 | -8097 |
| ALDOC | -8085 |
| CSNK2B | -8078 |
| PRELP | -8076 |
| ECHS1 | -8052 |
| SRM | -8050 |
| PGD | -8046 |
| RPS4X | -8028 |
| FAH | -8016 |
| ETHE1 | -8012 |
| ENO1 | -8009 |
| UQCRC1 | -7995 |
| SUMF2 | -7981 |
| PSAP | -7953 |
| ACY1 | -7941 |
| HSD17B12 | -7940 |
| SLC46A1 | -7928 |
| PCTP | -7923 |
| BGN | -7906 |
| POM121C | -7894 |
| POMC | -7890 |
| SUMF1 | -7868 |
| NDUFA13 | -7854 |
| NME4 | -7853 |
| MVK | -7851 |
| GDE1 | -7841 |
| ALDH4A1 | -7836 |
| NDUFB10 | -7825 |
| CACNA2D2 | -7817 |
| PLA2G2D | -7816 |
| NT5E | -7815 |
| HSD17B10 | -7814 |
| ADH1C | -7812 |
| STX1A | -7794 |
| AKR1A1 | -7793 |
| PIP4K2B | -7788 |
| ENO3 | -7787 |
| IMPDH1 | -7786 |
| ALOX5 | -7785 |
| RXRA | -7774 |
| TPR | -7773 |
| ITPKA | -7751 |
| B3GALT6 | -7746 |
| NDUFS7 | -7728 |
| ARF1 | -7717 |
| FITM2 | -7715 |
| PSMB10 | -7709 |
| GPX1 | -7708 |
| MLX | -7706 |
| PIK3R5 | -7704 |
| UQCR10 | -7703 |
| NDUFB7 | -7699 |
| FOLR2 | -7688 |
| NDUFS8 | -7687 |
| CYP4V2 | -7683 |
| HSCB | -7681 |
| NAXD | -7677 |
| GSTP1 | -7676 |
| SGSH | -7668 |
| BDH1 | -7659 |
| PLA2G15 | -7655 |
| SDHA | -7652 |
| MCAT | -7637 |
| ABCC3 | -7612 |
| NDUFC1 | -7608 |
| ADIPOR1 | -7605 |
| MED31 | -7602 |
| PNPLA2 | -7596 |
| ATP5ME | -7594 |
| GPC6 | -7588 |
| PI4K2A | -7579 |
| PSMB5 | -7576 |
| AGPAT1 | -7553 |
| HSD3B7 | -7549 |
| NDUFA1 | -7540 |
| FPGS | -7531 |
| UQCRFS1 | -7522 |
| GM2A | -7520 |
| HK1 | -7518 |
| NDOR1 | -7499 |
| PKM | -7496 |
| MCEE | -7471 |
| PEMT | -7457 |
| ENPP1 | -7453 |
| COX6B1 | -7448 |
| ARSA | -7432 |
| GNAI2 | -7430 |
| SREBF1 | -7428 |
| GUSB | -7411 |
| AMPD2 | -7409 |
| FITM1 | -7408 |
| MED25 | -7394 |
| PMVK | -7392 |
| OAZ1 | -7389 |
| FASN | -7379 |
| SEPHS2 | -7373 |
| FDX1 | -7349 |
| GPT2 | -7345 |
| NDUFA6 | -7341 |
| PIP5K1C | -7332 |
| CRYL1 | -7320 |
| PTGES | -7314 |
| DCTD | -7300 |
| PSME3 | -7280 |
| PSMB2 | -7268 |
| ACOT11 | -7262 |
| AMDHD1 | -7261 |
| GSTZ1 | -7252 |
| ATP5MC1 | -7251 |
| DNPH1 | -7250 |
| IDH3G | -7247 |
| PDK2 | -7246 |
| RBP4 | -7240 |
| TRMT112 | -7235 |
| ESRRA | -7230 |
| IL4I1 | -7228 |
| NAXE | -7226 |
| AOC2 | -7220 |
| PDPR | -7219 |
| GNG5 | -7218 |
| CYP26B1 | -7214 |
| SLC25A1 | -7210 |
| NUP62 | -7186 |
| COX6A1 | -7180 |
| B3GAT3 | -7173 |
| AGPAT3 | -7146 |
| NSDHL | -7125 |
| PTGS1 | -7121 |
| GGT7 | -7117 |
| ELOVL1 | -7114 |
| NDUFC2 | -7108 |
| MED11 | -7106 |
| PSMD2 | -7104 |
| UBE2I | -7091 |
| ITPA | -7089 |
| MED22 | -7086 |
| SLC25A20 | -7083 |
| PGM1 | -7071 |
| LGMN | -7062 |
| ACADS | -7058 |
| HS3ST3A1 | -7047 |
| ENPP6 | -7040 |
| DHCR7 | -7034 |
| HMOX2 | -7026 |
| ACLY | -7023 |
| PFKL | -7021 |
| HAGH | -7018 |
| TALDO1 | -7011 |
| APOE | -7009 |
| AAAS | -7005 |
| CSPG4 | -7003 |
| CPT2 | -6993 |
| KHK | -6980 |
| PPP2R1A | -6964 |
| NR1H2 | -6960 |
| APOM | -6954 |
| SLC27A1 | -6935 |
| BLVRB | -6922 |
| UQCR11 | -6919 |
| TYMP | -6914 |
| DTYMK | -6897 |
| CES2 | -6894 |
| GLTP | -6881 |
| UBA52 | -6880 |
| SLC16A3 | -6876 |
| TXN2 | -6874 |
| GAMT | -6862 |
| PTPMT1 | -6856 |
| PRKCA | -6845 |
| ATP5MC3 | -6841 |
| MOCS3 | -6839 |
| SCD | -6834 |
| GNB1 | -6821 |
| MTHFD1 | -6812 |
| VAC14 | -6779 |
| GPC5 | -6778 |
| PGLS | -6775 |
| EXT2 | -6767 |
| CNDP2 | -6755 |
| COX5B | -6747 |
| COX5A | -6735 |
| FAHD1 | -6732 |
| HEXA | -6728 |
| NDUFA3 | -6716 |
| PGAM2 | -6710 |
| PSMB6 | -6709 |
| ECI1 | -6692 |
| SDHC | -6686 |
| PYGB | -6678 |
| THTPA | -6664 |
| NDUFA4 | -6655 |
| PSMB3 | -6647 |
| COQ9 | -6644 |
| PNPO | -6637 |
| NDUFA8 | -6633 |
| ATP5MC2 | -6628 |
| MVD | -6623 |
| AHRR | -6611 |
| NDUFS5 | -6581 |
| HDAC3 | -6566 |
| SRR | -6565 |
| PIK3R1 | -6564 |
| RUFY1 | -6544 |
| ACOT13 | -6543 |
| PDZD11 | -6539 |
| PPM1L | -6532 |
| CA3 | -6530 |
| ACOT8 | -6527 |
| MT-ND6 | -6516 |
| DPEP2 | -6514 |
| ATP5F1E | -6502 |
| TBXAS1 | -6500 |
| NDUFB11 | -6495 |
| TPMT | -6473 |
| MED29 | -6467 |
| ALDH9A1 | -6458 |
| CS | -6457 |
| PSMD4 | -6452 |
| COX7B | -6445 |
| B3GALT4 | -6432 |
| GPD1 | -6430 |
| NDUFV3 | -6428 |
| NUP88 | -6417 |
| PUDP | -6413 |
| GGT1 | -6408 |
| AOC1 | -6397 |
| NUDT16 | -6381 |
| TK2 | -6380 |
| TPI1 | -6372 |
| SDSL | -6370 |
| RPL26L1 | -6364 |
| ADI1 | -6357 |
| SDHB | -6352 |
| AHCY | -6338 |
| PSMF1 | -6332 |
| SMPD4 | -6330 |
| BCAT1 | -6323 |
| GNA11 | -6316 |
| PLEKHA2 | -6310 |
| UBIAD1 | -6305 |
| PYCR2 | -6286 |
| GNG7 | -6266 |
| PYGM | -6261 |
| PITPNM1 | -6254 |
| CDIPT | -6250 |
| GSTM4 | -6249 |
| PLCD1 | -6244 |
| IP6K1 | -6243 |
| GPI | -6235 |
| POM121 | -6233 |
| B4GALT7 | -6219 |
| PTDSS2 | -6205 |
| ADCY8 | -6200 |
| ACAT2 | -6194 |
| UBB | -6193 |
| PNPLA4 | -6191 |
| ANGPTL4 | -6190 |
| UCP2 | -6186 |
| VDAC1 | -6184 |
| ACBD4 | -6183 |
| TNFAIP8 | -6163 |
| QARS1 | -6159 |
| ST3GAL1 | -6158 |
| PSMC5 | -6143 |
| INPP5J | -6130 |
| SLCO2B1 | -6126 |
| ESYT1 | -6124 |
| GPT | -6104 |
| AIMP2 | -6102 |
| SEC24C | -6100 |
| AIP | -6099 |
| QDPR | -6097 |
| GPS2 | -6090 |
| SPR | -6089 |
| PSMA7 | -6082 |
| XYLT1 | -6073 |
| GOT1 | -6071 |
| NDUFB4 | -6053 |
| UQCRQ | -6043 |
| NDUFA2 | -6040 |
| NAGLU | -6035 |
| INPPL1 | -6034 |
| UMPS | -6027 |
| CYP1B1 | -6012 |
| ALDH1A1 | -6011 |
| PGAM1 | -6006 |
| MINPP1 | -5997 |
| GSTM3 | -5996 |
| CKMT2 | -5993 |
| NR1H3 | -5984 |
| HSD11B1 | -5980 |
| GNA15 | -5973 |
| NDUFB2 | -5967 |
| KYAT1 | -5966 |
| PLCD3 | -5964 |
| MPC2 | -5958 |
| NDUFS3 | -5954 |
| PSMB7 | -5953 |
| GCAT | -5929 |
| STARD7 | -5923 |
| ATP5F1A | -5919 |
| SDS | -5918 |
| SUOX | -5909 |
| GLRX5 | -5903 |
| CEPT1 | -5897 |
| VAMP2 | -5893 |
| NUBP1 | -5889 |
| NDUFAB1 | -5886 |
| PGK1 | -5872 |
| PSMC4 | -5866 |
| TPST1 | -5860 |
| COX10 | -5837 |
| CHST13 | -5834 |
| THEM5 | -5830 |
| CYP2S1 | -5805 |
| SLC5A6 | -5801 |
| PPP2R5D | -5791 |
| MTHFD1L | -5778 |
| RPL39L | -5767 |
| ADCY1 | -5762 |
| DDO | -5748 |
| GRHPR | -5743 |
| MT-ND5 | -5735 |
| PPARA | -5728 |
| PSMC3 | -5726 |
| SREBF2 | -5725 |
| ALAS1 | -5717 |
| MBTPS1 | -5686 |
| AKR1B1 | -5682 |
| PTGES2 | -5671 |
| NOSIP | -5666 |
| GSTO1 | -5648 |
| NDUFB3 | -5630 |
| ACOT7 | -5628 |
| NADK | -5623 |
| ALOX5AP | -5621 |
| RHCE | -5618 |
| MARS1 | -5603 |
| PLBD1 | -5601 |
| SDC1 | -5597 |
| GNPDA1 | -5594 |
| MED8 | -5590 |
| ATP5PD | -5586 |
| PDXK | -5585 |
| TM7SF2 | -5577 |
| LPIN3 | -5572 |
| NT5C | -5571 |
| NDUFB8 | -5569 |
| ADCY9 | -5551 |
| ATP5PF | -5543 |
| NDUFS6 | -5537 |
| TCN2 | -5517 |
| EBP | -5511 |
| CHST14 | -5507 |
| ITPR3 | -5506 |
| SLC25A28 | -5504 |
| PPCDC | -5491 |
| PSMB1 | -5473 |
| TMLHE | -5466 |
| ADPGK | -5464 |
| EEFSEC | -5462 |
| ARSG | -5459 |
| GYS1 | -5458 |
| HEXB | -5455 |
| INPP5B | -5444 |
| MED24 | -5440 |
| CERS5 | -5438 |
| NDUFAF4 | -5432 |
| CAD | -5419 |
| PI4KA | -5413 |
| PHKG1 | -5399 |
| CKM | -5387 |
| TNFRSF21 | -5381 |
| SLC51A | -5373 |
| NUP93 | -5327 |
| COX7C | -5326 |
| SBF1 | -5325 |
| SCO1 | -5322 |
| ACSM5 | -5320 |
| CHP1 | -5319 |
| ACAA1 | -5304 |
| PLEKHA4 | -5294 |
| CD44 | -5281 |
| COX4I1 | -5248 |
| RPS14 | -5234 |
| GALE | -5230 |
| BTD | -5228 |
| ACAD8 | -5218 |
| PLPP6 | -5198 |
| PFAS | -5186 |
| IDUA | -5179 |
| GOT2 | -5177 |
| PSMB4 | -5168 |
| ADSL | -5167 |
| B3GALT1 | -5165 |
| ENTPD6 | -5163 |
| HOGA1 | -5153 |
| NUP37 | -5152 |
| NME1 | -5150 |
| ARV1 | -5149 |
| ATP5F1B | -5140 |
| MED10 | -5128 |
| LIPT1 | -5108 |
| PLCB3 | -5094 |
| PDHB | -5081 |
| GATM | -5079 |
| CIAO3 | -5065 |
| BCKDK | -5064 |
| ACAD10 | -5054 |
| NDUFB9 | -5052 |
| MPST | -5050 |
| CIDEC | -5048 |
| OAZ3 | -5046 |
| PLA2G4B | -5041 |
| PPARD | -5034 |
| EPHX2 | -5019 |
| NME2 | -5012 |
| NAGS | -5010 |
| DHODH | -5001 |
| ISCA2 | -5000 |
| ETNK2 | -4983 |
| SCO2 | -4979 |
| AMPD3 | -4970 |
| ACADVL | -4950 |
| PIK3R6 | -4934 |
| GNAS | -4913 |
| RPL27 | -4912 |
| ALDH3A2 | -4906 |
| RPL27A | -4896 |
| ALDH6A1 | -4889 |
| MED16 | -4886 |
| GLIPR1 | -4882 |
| COX19 | -4867 |
| HSD11B2 | -4862 |
| ACP5 | -4850 |
| SLC6A8 | -4848 |
| AGPAT2 | -4846 |
| GLB1L | -4843 |
| DCTPP1 | -4841 |
| SGPL1 | -4821 |
| MPC1 | -4820 |
| BCAT2 | -4811 |
| GNS | -4788 |
| CPNE1 | -4785 |
| CHST11 | -4784 |
| NUDT1 | -4771 |
| DLST | -4766 |
| SDC2 | -4765 |
| NEU1 | -4756 |
| RPL35 | -4745 |
| NEU3 | -4741 |
| HDC | -4735 |
| PRPS1 | -4720 |
| NUP188 | -4718 |
| PGP | -4717 |
| HTD2 | -4712 |
| SLC26A2 | -4703 |
| HMGCL | -4696 |
| COX16 | -4673 |
| PSMD9 | -4655 |
| OSBPL7 | -4632 |
| HS3ST3B1 | -4626 |
| FAU | -4625 |
| CA1 | -4616 |
| BLVRA | -4615 |
| AMPD1 | -4596 |
| TPST2 | -4585 |
| GNB3 | -4560 |
| COX14 | -4545 |
| AKR7A2 | -4535 |
| POLD1 | -4506 |
| ATP5MG | -4489 |
| ATP5PB | -4467 |
| LTA4H | -4460 |
| GPAT4 | -4459 |
| ECSIT | -4451 |
| SQLE | -4443 |
| RXRB | -4396 |
| STARD3 | -4391 |
| LYRM4 | -4389 |
| HYAL3 | -4388 |
| HAS2 | -4369 |
| PCBD1 | -4361 |
| FECH | -4356 |
| IVD | -4350 |
| MED15 | -4338 |
| MGST3 | -4328 |
| SULT1A2 | -4313 |
| ARNT | -4311 |
| PAPSS2 | -4292 |
| ACAA2 | -4284 |
| NDUFV1 | -4257 |
| PAPSS1 | -4246 |
| IDH2 | -4245 |
| COX6C | -4240 |
| PPT1 | -4238 |
| RETSAT | -4237 |
| MMACHC | -4234 |
| PLCB2 | -4232 |
| DDAH1 | -4227 |
| ATP5PO | -4216 |
| MBOAT7 | -4212 |
| TMEM186 | -4208 |
| SLC36A4 | -4206 |
| EPRS1 | -4204 |
| PLD4 | -4193 |
| ALDH1B1 | -4184 |
| PSMC2 | -4179 |
| GDPD5 | -4162 |
| ALAS2 | -4159 |
| NDUFS4 | -4157 |
| CKB | -4151 |
| RPL13 | -4148 |
| NFYC | -4144 |
| LMBRD1 | -4140 |
| SAR1B | -4109 |
| ISCU | -4107 |
| ACSF2 | -4094 |
| PTDSS1 | -4080 |
| TKT | -4075 |
| NDUFAF1 | -4070 |
| CYP21A2 | -4060 |
| TIMMDC1 | -4054 |
| PPP1CC | -4053 |
| RPL8 | -4049 |
| VKORC1L1 | -4048 |
| SCAP | -4041 |
| RPS18 | -4032 |
| RPS10 | -4028 |
| PIP4K2C | -4025 |
| UGDH | -4018 |
| NDUFB1 | -4014 |
| RPS29 | -4009 |
| GYG1 | -3994 |
| NDUFV2 | -3987 |
| SLC19A3 | -3978 |
| ADIPOR2 | -3977 |
| HNMT | -3962 |
| PRKACB | -3946 |
| HADHA | -3934 |
| GNMT | -3922 |
| DEGS2 | -3912 |
| MANBA | -3901 |
| DNM2 | -3899 |
| CA12 | -3879 |
| SLC37A4 | -3875 |
| RPS21 | -3873 |
| CDA | -3870 |
| PSMD10 | -3849 |
| GSTA4 | -3847 |
| TKFC | -3846 |
| PHKG2 | -3837 |
| AKR1C2 | -3821 |
| STK11 | -3818 |
| FDX2 | -3811 |
| ME2 | -3808 |
| KARS1 | -3801 |
| VDR | -3798 |
| MCCC2 | -3793 |
| MTMR14 | -3773 |
| MT-ATP8 | -3771 |
| PXMP2 | -3750 |
| RPS5 | -3741 |
| IDH3B | -3733 |
| TRIB3 | -3731 |
| HIBADH | -3722 |
| GSS | -3721 |
| CHST3 | -3720 |
| SDC4 | -3718 |
| ACAD9 | -3714 |
| NDUFA7 | -3704 |
| UROS | -3686 |
| MIGA2 | -3679 |
| MED12 | -3677 |
| SHMT1 | -3650 |
| EXT1 | -3644 |
| N6AMT1 | -3612 |
| NUP214 | -3603 |
| ABHD14B | -3576 |
| RPS11 | -3569 |
| RPL15 | -3543 |
| OAT | -3533 |
| GBE1 | -3532 |
| LPCAT3 | -3528 |
| RPLP1 | -3524 |
| RPL36 | -3523 |
| IDO1 | -3496 |
| RPL4 | -3472 |
| EPHX1 | -3469 |
| GLO1 | -3465 |
| PI4KB | -3450 |
| CPNE7 | -3449 |
| ACOX2 | -3446 |
| MMAB | -3427 |
| ACSF3 | -3403 |
| NMRK1 | -3402 |
| CYP27B1 | -3398 |
| MED7 | -3395 |
| DGAT2 | -3384 |
| PLB1 | -3372 |
| RPL31 | -3359 |
| VAPB | -3345 |
| OSBPL8 | -3333 |
| COX11 | -3330 |
| ASAH1 | -3322 |
| DBI | -3319 |
| PPCS | -3317 |
| PLD1 | -3314 |
| SPHK2 | -3299 |
| LPCAT1 | -3282 |
| PITPNM3 | -3281 |
| RPL23 | -3274 |
| GCDH | -3264 |
| IDH1 | -3258 |
| SLC22A5 | -3243 |
| TNFAIP8L3 | -3237 |
| COQ2 | -3231 |
| PSMA6 | -3225 |
| LDHA | -3223 |
| RPL10 | -3210 |
| DUOX2 | -3207 |
| RPS25 | -3191 |
| RPL7A | -3188 |
| PAOX | -3185 |
| SARS1 | -3156 |
| MED1 | -3129 |
| TRAP1 | -3119 |
| RAN | -3114 |
| CIAO2B | -3106 |
| RPL12 | -3105 |
| GMPR | -3089 |
| ARSI | -3079 |
| LYVE1 | -3078 |
| ATP5F1C | -3076 |
| TXNRD1 | -3072 |
| RPL29 | -3065 |
| OSBP | -3059 |
| RAE1 | -3056 |
| SELENOI | -3048 |
| PLPP1 | -3046 |
| PLA2G4A | -3044 |
| RPS19 | -3032 |
| PSME1 | -3031 |
| GNGT2 | -3028 |
| NUP98 | -3024 |
| RPL30 | -3017 |
| TXN | -3012 |
| CIAO1 | -3006 |
| LIPE | -2990 |
| MED27 | -2987 |
| RPL19 | -2986 |
| NRF1 | -2978 |
| RPS8 | -2974 |
| MDH1 | -2962 |
| GCSH | -2946 |
| POR | -2943 |
| XYLB | -2915 |
| ACOX1 | -2912 |
| OGN | -2906 |
| CARNS1 | -2904 |
| NDUFB6 | -2896 |
| UGP2 | -2885 |
| RPL35A | -2878 |
| RPLP0 | -2877 |
| APIP | -2871 |
| ADK | -2866 |
| CREBBP | -2822 |
| RGL1 | -2818 |
| PFKFB1 | -2806 |
| AMN | -2799 |
| SRD5A3 | -2797 |
| INPP5K | -2793 |
| DHRS7B | -2791 |
| NDUFAF2 | -2788 |
| PPIP5K1 | -2761 |
| ARSB | -2736 |
| FH | -2732 |
| PSMD7 | -2731 |
| RPL18 | -2728 |
| RPL18A | -2719 |
| RHD | -2718 |
| GLRX | -2715 |
| RPL13A | -2708 |
| SMPD3 | -2698 |
| RPL38 | -2691 |
| AGL | -2689 |
| PON3 | -2687 |
| NAT1 | -2677 |
| NUDT11 | -2674 |
| DHFR | -2664 |
| PLAAT4 | -2662 |
| UQCRH | -2661 |
| RPS27 | -2657 |
| PSMA5 | -2649 |
| CSNK1G2 | -2638 |
| PSMC1 | -2604 |
| PAICS | -2597 |
| MTHFS | -2590 |
| NME3 | -2582 |
| PDSS1 | -2579 |
| ADO | -2569 |
| RPS17 | -2555 |
| ACHE | -2554 |
| NUDT3 | -2543 |
| DDAH2 | -2533 |
| PDHA1 | -2529 |
| RBP1 | -2526 |
| PLIN1 | -2524 |
| FDFT1 | -2506 |
| PARP6 | -2498 |
| RPS23 | -2494 |
| RPS15 | -2484 |
| MECR | -2480 |
| GMPR2 | -2471 |
| KYAT3 | -2462 |
| DIO3 | -2451 |
| PSAT1 | -2431 |
| RARS1 | -2420 |
| FAAH | -2419 |
| PANK4 | -2417 |
| HS6ST3 | -2413 |
| RIDA | -2410 |
| DCXR | -2407 |
| RPL34 | -2389 |
| LRP8 | -2384 |
| IP6K2 | -2378 |
| KYNU | -2374 |
| ECI2 | -2346 |
| CIAPIN1 | -2342 |
| ABHD3 | -2339 |
| RPS3A | -2337 |
| PPP2CB | -2329 |
| RPL28 | -2326 |
| SLC44A1 | -2325 |
| SUCLG1 | -2318 |
| HADH | -2311 |
| SHPK | -2304 |
| HSD17B4 | -2299 |
| PARP16 | -2282 |
| PIP5K1A | -2262 |
| MED20 | -2249 |
| RPLP2 | -2239 |
| PTGDS | -2237 |
| GGPS1 | -2236 |
| NUP85 | -2218 |
| ABCA1 | -2212 |
| PCYT1A | -2207 |
| AK2 | -2197 |
| PCCB | -2182 |
| HS2ST1 | -2178 |
| XYLT2 | -2174 |
| NUBPL | -2171 |
| NCOR1 | -2161 |
| NMNAT1 | -2155 |
| GSTK1 | -2139 |
| LTC4S | -2136 |
| PSMD14 | -2133 |
| RPL32 | -2131 |
| CDO1 | -2123 |
| FDXR | -2115 |
| AGRN | -2113 |
| FUT11 | -2104 |
| RPL3L | -2091 |
| RPL23A | -2081 |
| RPS12 | -2076 |
| MAOA | -2073 |
| HMBS | -2059 |
| SLC22A3 | -2052 |
| RPS15A | -2051 |
| RDH11 | -2043 |
| MBTPS2 | -2040 |
| ACOT2 | -2003 |
| HAS3 | -1971 |
| VCAN | -1970 |
| BPNT2 | -1967 |
| ACSL1 | -1947 |
| GBA2 | -1936 |
| CYP2R1 | -1921 |
| NDC1 | -1920 |
| AGMAT | -1911 |
| ACBD6 | -1910 |
| MOCS2 | -1900 |
| DSEL | -1896 |
| DGAT1 | -1889 |
| NADSYN1 | -1877 |
| ACOT4 | -1874 |
| MED6 | -1861 |
| ABHD10 | -1854 |
| SLC27A5 | -1852 |
| CD320 | -1842 |
| ADIPOQ | -1833 |
| COQ10A | -1825 |
| HPSE | -1810 |
| PHKA2 | -1809 |
| PIK3CG | -1798 |
| SUMO2 | -1786 |
| PSMD1 | -1782 |
| DEGS1 | -1772 |
| RPL10A | -1766 |
| PSMA4 | -1756 |
| SCLY | -1751 |
| RPS20 | -1746 |
| SLC2A1 | -1743 |
| LUM | -1737 |
| RPL37A | -1736 |
| FUT10 | -1693 |
| RPS28 | -1692 |
| NUDT13 | -1691 |
| BPGM | -1653 |
| THRSP | -1648 |
| RPS3 | -1643 |
| IMPDH2 | -1641 |
| DCK | -1616 |
| DECR2 | -1601 |
| PSME2 | -1591 |
| STARD10 | -1584 |
| RPS7 | -1576 |
| ACSS2 | -1558 |
| PECR | -1552 |
| OAZ2 | -1550 |
| SLC26A1 | -1543 |
| COX7A2L | -1534 |
| ALOX12 | -1521 |
| RPL37 | -1517 |
| AKR7L | -1513 |
| CHST15 | -1492 |
| PSMD11 | -1483 |
| SULT1A3 | -1481 |
| NDUFAF6 | -1480 |
| DPYD | -1477 |
| ETFA | -1469 |
| FDPS | -1460 |
| HPD | -1438 |
| PSMD5 | -1433 |
| CIDEA | -1426 |
| CRLS1 | -1423 |
| ESYT2 | -1420 |
| PHKA1 | -1399 |
| CYP27A1 | -1397 |
| RPS24 | -1390 |
| HLCS | -1371 |
| AGPAT4 | -1352 |
| NAT8L | -1332 |
| SLC51B | -1324 |
| NDUFA5 | -1323 |
| COQ5 | -1303 |
| SERINC5 | -1298 |
| PSMA2 | -1286 |
| RPL3 | -1283 |
| UCP3 | -1280 |
| KMO | -1276 |
| IDH3A | -1272 |
| PISD | -1270 |
| GNPDA2 | -1252 |
| NDUFA12 | -1250 |
| UCKL1 | -1246 |
| RPS6 | -1245 |
| TDO2 | -1225 |
| SIN3A | -1221 |
| MORC2 | -1198 |
| CSNK2A1 | -1195 |
| BPNT1 | -1193 |
| B4GALT4 | -1184 |
| ARSD | -1170 |
| THRAP3 | -1164 |
| SEC24D | -1154 |
| PIAS4 | -1127 |
| MT-CO3 | -1115 |
| NT5M | -1109 |
| SLC25A21 | -1100 |
| ACOX3 | -1077 |
| RPL26 | -1044 |
| SLC27A3 | -1041 |
| CHD9 | -1030 |
| ACOT9 | -1029 |
| IQGAP1 | -1025 |
| COX18 | -1013 |
| ADCY7 | -1010 |
| MT-CO2 | -988 |
| DECR1 | -987 |
| RRM1 | -967 |
| GSTM2 | -966 |
| ABCC1 | -953 |
| HS3ST1 | -933 |
| NCOA6 | -932 |
| GART | -919 |
| RPL21 | -907 |
| NUDT5 | -895 |
| ALAD | -888 |
| PLEKHA1 | -864 |
| GCKR | -862 |
| HSD17B8 | -861 |
| CHST6 | -856 |
| CROT | -850 |
| RPL11 | -848 |
| TAZ | -842 |
| PLCD4 | -832 |
| RPL41 | -812 |
| PRKAR1B | -805 |
| ACAN | -799 |
| CYB5B | -798 |
| STS | -794 |
| PSMD13 | -754 |
| EEF1E1 | -752 |
| PPAT | -746 |
| FUT7 | -742 |
| NUP205 | -738 |
| GLUD1 | -728 |
| ARG2 | -723 |
| SLC25A10 | -722 |
| MLYCD | -713 |
| PIP4K2A | -710 |
| OPLAH | -709 |
| STARD5 | -700 |
| NUDT19 | -689 |
| ESD | -686 |
| NR1D1 | -676 |
| B4GALT1 | -661 |
| MED21 | -660 |
| NFS1 | -656 |
| NUP42 | -641 |
| ABCC5 | -621 |
| MMUT | -618 |
| RPL17 | -614 |
| PIK3R4 | -607 |
| AK6 | -601 |
| HPSE2 | -564 |
| GUK1 | -544 |
| IPPK | -541 |
| SUCLA2 | -529 |
| CACNB3 | -523 |
| AHCYL1 | -485 |
| RPL6 | -483 |
| SPTLC2 | -475 |
| CPNE3 | -465 |
| ISYNA1 | -459 |
| RNLS | -453 |
| RPS16 | -451 |
| CYP11A1 | -443 |
| NDUFB5 | -429 |
| LSS | -423 |
| RPS2 | -411 |
| ASL | -391 |
| DHFR2 | -385 |
| RRM2B | -368 |
| RPL14 | -367 |
| PLAAT3 | -362 |
| CHAC2 | -355 |
| D2HGDH | -341 |
| TECRL | -324 |
| NDUFS1 | -297 |
| RPL24 | -289 |
| RTEL1 | -278 |
| CYP2U1 | -276 |
| HYAL2 | -264 |
| DSE | -254 |
| PRXL2B | -251 |
| PLAAT5 | -248 |
| EP300 | -244 |
| PSMB8 | -235 |
| ELOVL2 | -217 |
| ENOPH1 | -191 |
| MOCOS | -189 |
| SLC16A1 | -162 |
| RPL5 | -160 |
| NUP153 | -156 |
| PRKAR2A | -154 |
| COQ3 | -147 |
| MTMR1 | -137 |
| FBP2 | -135 |
| SLC25A15 | -112 |
| SGMS1 | -110 |
| RAP1A | -109 |
| PIK3CB | -106 |
| FAM120B | -95 |
| MT-ND4 | -94 |
| SMARCD3 | -65 |
| PSME4 | -48 |
| PIPOX | -47 |
| SMPD2 | -28 |
| DMAC2L | -25 |
| MMS19 | -13 |
| RPS9 | 11 |
| HSD17B7 | 20 |
| PSMD6 | 26 |
| PYGL | 29 |
| HSD17B11 | 56 |
| SP1 | 60 |
| ABHD4 | 66 |
| CHKB | 68 |
| ASNS | 108 |
| CSNK2A2 | 111 |
| TK1 | 120 |
| SLC25A12 | 133 |
| CHPT1 | 149 |
| PARP10 | 153 |
| GCLC | 180 |
| AFMID | 197 |
| GLYATL1 | 210 |
| RPS27L | 222 |
| RPS27A | 229 |
| CYP4B1 | 252 |
| GNPAT | 297 |
| ADH5 | 298 |
| ERCC2 | 315 |
| MTMR3 | 321 |
| ACSM3 | 344 |
| RPL22 | 345 |
| MTMR2 | 362 |
| PSMA1 | 379 |
| RPL39 | 390 |
| DLAT | 403 |
| MT-ND2 | 425 |
| PPOX | 450 |
| PANK2 | 460 |
| UQCRC2 | 468 |
| MAN2C1 | 476 |
| QPRT | 481 |
| SLC3A2 | 494 |
| COQ6 | 498 |
| SERINC3 | 500 |
| GPD1L | 504 |
| TBL1X | 506 |
| RPS4Y1 | 514 |
| TSPOAP1 | 518 |
| GNG10 | 545 |
| DCN | 553 |
| ACSL4 | 565 |
| MED26 | 568 |
| SIN3B | 588 |
| MID1IP1 | 590 |
| AZIN2 | 591 |
| BCO2 | 641 |
| MARCKS | 645 |
| PHYKPL | 649 |
| GPC1 | 659 |
| CDS2 | 699 |
| MT-CO1 | 720 |
| GSTT2B | 741 |
| PDSS2 | 745 |
| MGST1 | 767 |
| ST3GAL4 | 774 |
| ACOXL | 776 |
| MSMO1 | 789 |
| OSBPL2 | 791 |
| DMGDH | 804 |
| SERINC1 | 808 |
| GMPS | 825 |
| THEM4 | 832 |
| RAB4A | 839 |
| PLD6 | 851 |
| HSPG2 | 885 |
| CRYM | 898 |
| GYG2 | 916 |
| MRI1 | 918 |
| ABHD5 | 931 |
| SEC23A | 932 |
| MAPKAPK2 | 933 |
| GALT | 941 |
| DERA | 944 |
| ADH1B | 949 |
| SULT4A1 | 976 |
| GPAM | 992 |
| DCT | 995 |
| RPS13 | 1006 |
| MTHFR | 1038 |
| ACSL3 | 1047 |
| PDK3 | 1048 |
| SC5D | 1065 |
| INPP5D | 1076 |
| PTGES3 | 1088 |
| MT-ATP6 | 1105 |
| NUDT15 | 1121 |
| SMS | 1140 |
| ST3GAL3 | 1150 |
| BST1 | 1165 |
| CYP2D6 | 1169 |
| IDS | 1175 |
| ENTPD7 | 1189 |
| MTMR7 | 1200 |
| HSD17B14 | 1204 |
| HPGD | 1207 |
| UQCRB | 1227 |
| ME1 | 1234 |
| ELOVL4 | 1260 |
| PRKAG2 | 1283 |
| FADS1 | 1300 |
| NT5C2 | 1323 |
| SGPP1 | 1333 |
| IARS1 | 1339 |
| ISCA1 | 1365 |
| SGPP2 | 1366 |
| LPIN2 | 1381 |
| ADCY6 | 1400 |
| NUDT12 | 1401 |
| HSP90AB1 | 1424 |
| HADHB | 1425 |
| CPS1 | 1442 |
| GK | 1454 |
| PIK3CD | 1455 |
| CERS6 | 1461 |
| TIAM2 | 1462 |
| PLA2G2A | 1477 |
| DUOX1 | 1484 |
| INPP5E | 1486 |
| LIPT2 | 1515 |
| PRKAR2B | 1526 |
| ALDH1L1 | 1539 |
| SLC44A5 | 1541 |
| MTARC1 | 1548 |
| SAMHD1 | 1554 |
| CHAC1 | 1568 |
| AGPS | 1581 |
| SBF2 | 1598 |
| PARP4 | 1613 |
| FTCD | 1617 |
| ACAT1 | 1619 |
| SORD | 1625 |
| CALM1 | 1638 |
| MTRR | 1643 |
| PHYH | 1705 |
| AS3MT | 1715 |
| RPL7 | 1738 |
| ACP6 | 1753 |
| SLC16A8 | 1763 |
| ENPP3 | 1770 |
| PGS1 | 1780 |
| HACD2 | 1783 |
| BPHL | 1784 |
| MMADHC | 1787 |
| NDUFAF7 | 1789 |
| B4GALT5 | 1807 |
| ACAD11 | 1830 |
| GSR | 1865 |
| COA1 | 1872 |
| RAB14 | 1901 |
| CERS1 | 1935 |
| PRPS2 | 1942 |
| MT-ND3 | 1944 |
| OCRL | 1952 |
| ACER3 | 1958 |
| DIO2 | 1959 |
| ADHFE1 | 1961 |
| SLC44A3 | 1985 |
| PHGDH | 1999 |
| PANK3 | 2021 |
| AK4 | 2042 |
| GDPD3 | 2068 |
| NAPRT | 2077 |
| EPM2A | 2084 |
| NUP155 | 2114 |
| GLYATL2 | 2115 |
| CA5B | 2118 |
| NUP35 | 2129 |
| GLCE | 2143 |
| PPP1CB | 2156 |
| NUP54 | 2157 |
| TMEM126B | 2158 |
| PIK3CA | 2176 |
| MTF1 | 2179 |
| MED28 | 2185 |
| CMPK1 | 2208 |
| PLEKHA8 | 2221 |
| AMACR | 2226 |
| AIMP1 | 2228 |
| CPOX | 2251 |
| PLD2 | 2287 |
| SLC25A17 | 2290 |
| PPA2 | 2296 |
| FIG4 | 2301 |
| AASDHPPT | 2304 |
| PRKAA2 | 2305 |
| PPT2 | 2306 |
| SPTLC1 | 2312 |
| IMPA1 | 2409 |
| PARP9 | 2423 |
| KPNB1 | 2425 |
| SCP2 | 2435 |
| MED13L | 2448 |
| NUP43 | 2453 |
| LPCAT2 | 2461 |
| SPTSSA | 2472 |
| RPE | 2477 |
| SLC25A44 | 2518 |
| SACM1L | 2560 |
| MTMR6 | 2562 |
| DLD | 2572 |
| MTMR4 | 2584 |
| PPA1 | 2589 |
| MAT2B | 2590 |
| PI4K2B | 2613 |
| SMOX | 2647 |
| HACD3 | 2660 |
| PDP2 | 2666 |
| RPL36A | 2688 |
| SLC35B3 | 2700 |
| SLC19A1 | 2701 |
| ACSS1 | 2704 |
| TGS1 | 2707 |
| PDK4 | 2727 |
| PFKM | 2765 |
| FABP4 | 2782 |
| NNT | 2790 |
| HMMR | 2793 |
| SGMS2 | 2799 |
| FXN | 2807 |
| GALC | 2830 |
| MTHFD2 | 2840 |
| PLA2G12A | 2871 |
| HPRT1 | 2897 |
| PARP8 | 2899 |
| PLA2G4C | 2922 |
| DBT | 2950 |
| NUDT10 | 2962 |
| GLA | 2965 |
| LPGAT1 | 2968 |
| GNG12 | 2973 |
| MED4 | 2991 |
| SDHD | 3003 |
| ETFDH | 3008 |
| NDUFS2 | 3010 |
| PLIN2 | 3020 |
| SLC25A14 | 3046 |
| AUH | 3047 |
| GPC4 | 3048 |
| CCNC | 3078 |
| ELOVL5 | 3103 |
| GPAT2 | 3108 |
| LPL | 3111 |
| PLA2G5 | 3112 |
| CYSLTR2 | 3130 |
| HAAO | 3157 |
| CYB5A | 3159 |
| RANBP2 | 3171 |
| RPSA | 3175 |
| RFK | 3197 |
| CLOCK | 3204 |
| COX15 | 3245 |
| UBC | 3246 |
| ACACA | 3247 |
| ZDHHC21 | 3269 |
| KDSR | 3274 |
| PRKAR1A | 3280 |
| HACL1 | 3285 |
| GCLM | 3292 |
| OSBPL9 | 3307 |
| MTHFD2L | 3354 |
| PPIP5K2 | 3400 |
| PNPLA7 | 3412 |
| INPP4A | 3415 |
| MLXIPL | 3416 |
| VAPA | 3437 |
| NDUFA9 | 3450 |
| MCCC1 | 3451 |
| GNG2 | 3460 |
| NCOA2 | 3470 |
| PIK3C3 | 3477 |
| NDUFA10 | 3483 |
| GLYCTK | 3508 |
| PPP2CA | 3519 |
| SYNJ1 | 3523 |
| MTMR12 | 3528 |
| CARNMT1 | 3543 |
| EHHADH | 3548 |
| DDHD1 | 3577 |
| SEC24A | 3580 |
| B3GALNT1 | 3593 |
| MAOB | 3616 |
| CA4 | 3629 |
| PFKFB4 | 3630 |
| FAR2 | 3634 |
| MMAA | 3645 |
| MED14 | 3649 |
| PSMD12 | 3658 |
| NUP133 | 3662 |
| HSP90AA1 | 3693 |
| SUCLG2 | 3699 |
| MT-ND1 | 3710 |
| ENTPD5 | 3712 |
| CSAD | 3713 |
| NUDT7 | 3717 |
| LYPLA1 | 3739 |
| PITPNB | 3744 |
| AZIN1 | 3763 |
| PFKFB2 | 3768 |
| MED13 | 3780 |
| PSMC6 | 3801 |
| CDS1 | 3815 |
| AMD1 | 3824 |
| CYP51A1 | 3832 |
| SLC44A2 | 3834 |
| G0S2 | 3842 |
| PNMT | 3846 |
| ADCY2 | 3878 |
| SLC37A1 | 3929 |
| MGLL | 3938 |
| NCOA1 | 3941 |
| TYMS | 3942 |
| SEC24B | 3945 |
| ADCY5 | 4004 |
| PHKB | 4007 |
| ORMDL1 | 4009 |
| STARD3NL | 4022 |
| KCNB1 | 4031 |
| ITPR2 | 4036 |
| DHTKD1 | 4065 |
| ACSS3 | 4073 |
| ADPRM | 4106 |
| PSMB9 | 4121 |
| AK5 | 4128 |
| MED23 | 4134 |
| PITPNM2 | 4161 |
| MTAP | 4167 |
| PNPLA8 | 4187 |
| HMOX1 | 4200 |
| GCK | 4205 |
| CYP26A1 | 4216 |
| BHMT2 | 4226 |
| HMGCR | 4227 |
| AK8 | 4267 |
| SAMD8 | 4302 |
| ENPP2 | 4345 |
| SEH1L | 4352 |
| OXCT1 | 4354 |
| HSD17B13 | 4382 |
| CPT1B | 4390 |
| ALDH7A1 | 4408 |
| PPP1R3C | 4413 |
| HSD17B3 | 4414 |
| LRPPRC | 4418 |
| ENTPD3 | 4420 |
| PHOSPHO1 | 4443 |
| NUP58 | 4488 |
| PPARG | 4509 |
| ACSBG2 | 4513 |
| GNB4 | 4535 |
| KCNS3 | 4547 |
| B3GNT4 | 4549 |
| BDH2 | 4552 |
| PTPN13 | 4569 |
| CMBL | 4587 |
| COQ7 | 4599 |
| CHKA | 4614 |
| TPK1 | 4623 |
| OSBPL3 | 4626 |
| CDK8 | 4636 |
| ELOVL6 | 4642 |
| GGT5 | 4668 |
| RPIA | 4687 |
| GPHN | 4694 |
| CERT1 | 4722 |
| RPL36AL | 4730 |
| AKR7A3 | 4736 |
| DARS1 | 4742 |
| AKR1C1 | 4766 |
| UCK2 | 4774 |
| MGST2 | 4788 |
| CPT1A | 4793 |
| LPCAT4 | 4805 |
| PRODH | 4809 |
| ST3GAL2 | 4843 |
| RPL9 | 4853 |
| GNA14 | 4861 |
| OMD | 4868 |
| PDHX | 4872 |
| B3GNT7 | 4875 |
| PRKD3 | 4879 |
| MED30 | 4884 |
| B4GALT3 | 4889 |
| WASL | 4892 |
| ACADM | 4910 |
| CACNA1D | 4922 |
| GGCT | 4923 |
| TPH1 | 4953 |
| SLC25A32 | 4986 |
| AMT | 4989 |
| FADS2 | 4994 |
| NAALAD2 | 5006 |
| B3GNT2 | 5007 |
| FUT2 | 5016 |
| SLC23A2 | 5048 |
| ADRA2C | 5056 |
| LDHB | 5058 |
| ARNT2 | 5069 |
| PSMA3 | 5077 |
| RPL22L1 | 5078 |
| ADCY3 | 5125 |
| PLA2G6 | 5139 |
| HMGCLL1 | 5145 |
| CYGB | 5151 |
| CERK | 5157 |
| OSBPL6 | 5194 |
| CYP2E1 | 5195 |
| ADAL | 5212 |
| MTR | 5215 |
| PPARGC1B | 5221 |
| NUP160 | 5248 |
| CSGALNACT1 | 5250 |
| MED17 | 5257 |
| ENTPD4 | 5285 |
| NCOA3 | 5317 |
| MTMR10 | 5320 |
| NUDT9 | 5362 |
| SEM1 | 5372 |
| GPC2 | 5376 |
| PLCE1 | 5386 |
| ABCB7 | 5406 |
| NQO1 | 5421 |
| AKAP5 | 5422 |
| DUT | 5483 |
| RAB5A | 5503 |
| SECISBP2 | 5536 |
| ACACB | 5537 |
| HELZ2 | 5538 |
| INPP5F | 5548 |
| SULT1A4 | 5554 |
| INPP5A | 5608 |
| MT-CYB | 5619 |
| CHDH | 5661 |
| ENO2 | 5690 |
| PGM2 | 5693 |
| ASRGL1 | 5738 |
| MTMR9 | 5751 |
| NUP50 | 5758 |
| SLC35D1 | 5788 |
| MOCS1 | 5801 |
| LPIN1 | 5813 |
| ANKRD1 | 5815 |
| PLCG1 | 5830 |
| PLA2R1 | 5841 |
| CA13 | 5844 |
| HK2 | 5854 |
| FAR1 | 5884 |
| SAT1 | 5910 |
| CYP3A5 | 5917 |
| SLC35D2 | 5919 |
| HIBCH | 5933 |
| PTGR1 | 5945 |
| GPD2 | 5952 |
| LARS1 | 6001 |
| PLEKHA6 | 6009 |
| PNP | 6038 |
| MIGA1 | 6056 |
| PIKFYVE | 6071 |
| B3GNT3 | 6092 |
| CTH | 6093 |
| CYP39A1 | 6138 |
| PRKD2 | 6146 |
| ALDH1L2 | 6166 |
| HILPDA | 6172 |
| ARSK | 6184 |
| PRKD1 | 6205 |
| DDHD2 | 6257 |
| ESYT3 | 6303 |
| B4GALNT1 | 6325 |
| NMNAT3 | 6334 |
| CDK19 | 6340 |
| IMPA2 | 6342 |
| ABCD4 | 6343 |
| GDPD1 | 6352 |
| SULT1B1 | 6366 |
| ARSJ | 6373 |
| ME3 | 6390 |
| SCD5 | 6393 |
| CYP46A1 | 6402 |
| ETNK1 | 6403 |
| B4GALNT2 | 6425 |
| STARD4 | 6460 |
| LRP12 | 6478 |
| ACSL6 | 6486 |
| NOS3 | 6496 |
| ABCB4 | 6517 |
| CBSL | 6527 |
| ACBD5 | 6530 |
| MTM1 | 6552 |
| TBL1XR1 | 6553 |
| STXBP1 | 6560 |
| CA2 | 6562 |
| HACD4 | 6579 |
| PSTK | 6590 |
| PPARGC1A | 6593 |
| IPMK | 6606 |
| GNAQ | 6700 |
| ABCG2 | 6701 |
| PARP14 | 6718 |
| GNB5 | 6724 |
| CHRM3 | 6737 |
| IDI1 | 6754 |
| PIK3R3 | 6755 |
| AK9 | 6766 |
| CHST7 | 6768 |
| RORA | 6791 |
| OSBPL1A | 6793 |
| CYP4F12 | 6822 |
| RBKS | 6856 |
| GLYAT | 6866 |
| CYP19A1 | 6880 |
| HYKK | 6882 |
| UPP1 | 6892 |
| CTPS1 | 6894 |
| GLS | 6907 |
| GPAT3 | 6914 |
| ACADSB | 6943 |
| ACOT1 | 6960 |
| VNN1 | 6989 |
| PTEN | 7006 |
| HACD1 | 7028 |
| RRM2 | 7053 |
| GNG4 | 7087 |
| PDP1 | 7094 |
| INPP1 | 7097 |
| AOX1 | 7130 |
| SLC25A37 | 7141 |
| INSIG2 | 7149 |
| AGK | 7150 |
| LIAS | 7161 |
| SEPSECS | 7203 |
| PGM2L1 | 7240 |
| SLC25A16 | 7274 |
| HMGCS1 | 7279 |
| RIMKLA | 7308 |
| GADL1 | 7360 |
| GPIHBP1 | 7380 |
| SNAP25 | 7382 |
| CYCS | 7385 |
| NDUFAF5 | 7395 |
| CTRC | 7401 |
| GSTO2 | 7406 |
| NDST1 | 7485 |
| MBOAT1 | 7491 |
| PLEKHA3 | 7500 |
| LBR | 7504 |
| BCKDHB | 7513 |
| GCH1 | 7524 |
| CTPS2 | 7530 |
| ADH4 | 7550 |
| B3GAT2 | 7557 |
| NPAS2 | 7575 |
| COQ10B | 7585 |
| MTMR8 | 7605 |
| PON2 | 7607 |
| AASS | 7660 |
| CYP7B1 | 7672 |
| AGPAT5 | 7675 |
| PANK1 | 7701 |
| SYT5 | 7738 |
| B3GAT1 | 7740 |
| COX20 | 7745 |
| ACSM2B | 7765 |
| SLC52A3 | 7772 |
| HAS1 | 7776 |
| ENTPD2 | 7778 |
| ACSM4 | 7783 |
| CAV1 | 7793 |
| ACSBG1 | 7811 |
| SYNJ2 | 7815 |
| AGMO | 7821 |
| B4GALT6 | 7825 |
| ACER2 | 7831 |
| PIP5K1B | 7835 |
| PTGR2 | 7838 |
| ACSL5 | 7850 |
| FLVCR1 | 7865 |
| CSGALNACT2 | 7871 |
| RAPGEF3 | 7895 |
| L2HGDH | 7898 |
| FOLH1 | 7928 |
| PLA1A | 7934 |
| UGCG | 7954 |
| PRKAB2 | 7959 |
| CBR4 | 7966 |
| GSTT2 | 7983 |
| CYP1A2 | 8029 |
| PTGIS | 8043 |
| SRD5A1 | 8055 |
| CACNB2 | 8060 |
| CHST1 | 8070 |
| AKR1B15 | 8083 |
| AADAT | 8123 |
| NFYB | 8132 |
| NFYA | 8142 |
| INMT | 8160 |
| MTARC2 | 8173 |
| MBOAT2 | 8174 |
| NT5C3A | 8181 |
| CHSY3 | 8190 |
| LCLAT1 | 8212 |
| CHSY1 | 8230 |
| AHR | 8294 |
| AGT | 8316 |
| ACADL | 8319 |
| BRIP1 | 8329 |
| TNFAIP8L1 | 8343 |
| NADK2 | 8347 |
| OSBPL10 | 8435 |
| GPC3 | 8446 |
| SPNS2 | 8447 |
| PPM1K | 8448 |
| PPP2R1B | 8460 |
| PIK3C2B | 8495 |
| MAT2A | 8500 |
| ENTPD1 | 8516 |
| ITPKC | 8556 |
| PCK1 | 8565 |
| PCCA | 8572 |
| PIK3C2A | 8597 |
| ASPA | 8621 |
| PLCB1 | 8642 |
| SLC6A7 | 8645 |
| CD36 | 8666 |
| CUBN | 8669 |
| HAL | 8681 |
| PLA2G4D | 8722 |
| PLPP2 | 8738 |
| CYP2C9 | 8746 |
| GLDC | 8751 |
| CHST5 | 8759 |
| ST3GAL6 | 8762 |
| STAB2 | 8771 |
| SLC25A13 | 8791 |
| PLEKHA5 | 8801 |
| NMNAT2 | 8836 |
| PTS | 8856 |
| PRKG2 | 8883 |
| ARNTL | 8892 |
| GNG11 | 8919 |
| GPCPD1 | 8959 |
| SLC25A27 | 8962 |
| FHL2 | 8972 |
| PLCG2 | 8985 |
| INSIG1 | 9007 |
| ADRA2A | 9012 |
| LRP2 | 9056 |
| CACNA1C | 9115 |
| FMO2 | 9124 |
| AOC3 | 9133 |
| INPP4B | 9161 |
| HSD17B2 | 9162 |
| PDK1 | 9206 |
| ACBD7 | 9207 |
| NUP107 | 9235 |
| CACNA1A | 9247 |
| ODC1 | 9250 |
| FABP5 | 9265 |
| NUDT4 | 9316 |
| GNAI1 | 9325 |
| SLC19A2 | 9341 |
| UPB1 | 9390 |
| ITPKB | 9391 |
| NAMPT | 9415 |
| ADCY4 | 9424 |
| TPH2 | 9428 |
| SPTLC3 | 9451 |
| ITPR1 | 9487 |
| SPHK1 | 9530 |
| AKR1C3 | 9552 |
| AK7 | 9578 |
| RIMKLB | 9588 |
| ADA | 9626 |
| GRHL1 | 9636 |
| FMO1 | 9676 |
| ACSM2A | 9742 |
| CH25H | 9776 |
| FUT1 | 9802 |
| SULT1C2 | 9808 |
| FMO3 | 9829 |
| TPO | 9831 |
| BMX | 9846 |
| ABO | 9847 |
| SULT1C4 | 9868 |
| LDLR | 9925 |
| VNN2 | 9938 |
| PTGS2 | 9943 |
| CACNA1E | 9958 |
| RAPGEF4 | 9960 |
| PLCB4 | 10057 |
| SLC7A5 | 10071 |
| ELOVL7 | 10072 |
| PFKFB3 | 10116 |
| CYP4F3 | 10126 |
| GSTM5 | 10128 |
| ABCB1 | 10136 |
| NOSTRIN | 10152 |
| SLC2A3 | 10153 |
Innate Immune System
| 561 | |
|---|---|
| set | Innate Immune System |
| setSize | 939 |
| pANOVA | 3.77e-39 |
| s.dist | -0.252 |
| p.adjustANOVA | 2.74e-36 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| MUC20 | -9146 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| DEFB1 | -9133 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| MUC20 | -9146 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| DEFB1 | -9133 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| SIRPB1 | -9101 |
| IGHV2-5 | -9098 |
| NCF1 | -9092 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| MAPK7 | -9047 |
| CYB5R3 | -9018 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| SERPINA1 | -8963 |
| IGHV1-2 | -8953 |
| GRN | -8951 |
| GAA | -8936 |
| LAMP1 | -8930 |
| OSCAR | -8923 |
| CKAP4 | -8916 |
| TMBIM1 | -8914 |
| IGHV1-46 | -8910 |
| IGKV2D-28 | -8875 |
| IGHG4 | -8874 |
| CTSA | -8873 |
| S100A11 | -8865 |
| IGKV3-11 | -8864 |
| CD81 | -8856 |
| CD68 | -8853 |
| ALDH3B1 | -8840 |
| IGKV1D-39 | -8828 |
| NCSTN | -8815 |
| FGR | -8811 |
| ORMDL3 | -8807 |
| IGLV3-21 | -8806 |
| CSTB | -8805 |
| SURF4 | -8799 |
| RNASE2 | -8797 |
| C1QC | -8796 |
| UNC93B1 | -8794 |
| IGLV3-25 | -8773 |
| PIK3R2 | -8767 |
| CYBA | -8747 |
| CD4 | -8741 |
| RNASE6 | -8739 |
| RNF135 | -8690 |
| S100B | -8689 |
| APOB | -8671 |
| ITLN1 | -8655 |
| HK3 | -8652 |
| ALDOA | -8627 |
| ATP6V0E2 | -8624 |
| ITGB2 | -8620 |
| CFB | -8616 |
| IGHV3-33 | -8608 |
| ADGRE5 | -8603 |
| TUBB | -8597 |
| SIGLEC14 | -8594 |
| MS4A2 | -8592 |
| WAS | -8588 |
| IGLV2-14 | -8572 |
| ANPEP | -8527 |
| C1QB | -8526 |
| MAN2B1 | -8524 |
| DOK3 | -8498 |
| CTSB | -8493 |
| PRKACA | -8490 |
| LAIR1 | -8472 |
| COMMD9 | -8460 |
| BPIFB4 | -8459 |
| SLC11A1 | -8457 |
| CD180 | -8455 |
| TREM1 | -8429 |
| IRAK1 | -8427 |
| ATP6V0C | -8415 |
| CLU | -8383 |
| ATG7 | -8380 |
| LILRB2 | -8379 |
| ATP6V1F | -8374 |
| PTPN6 | -8357 |
| TYROBP | -8356 |
| PSMD3 | -8328 |
| GPR84 | -8320 |
| PLD3 | -8311 |
| RHOG | -8288 |
| SIGLEC16 | -8279 |
| TOLLIP | -8276 |
| GHDC | -8267 |
| FUCA2 | -8249 |
| HCK | -8242 |
| BCL2L1 | -8236 |
| PIN1 | -8233 |
| DPP7 | -8205 |
| GLB1 | -8189 |
| MAPKAPK3 | -8188 |
| LYZ | -8186 |
| FOLR3 | -8171 |
| PSMD8 | -8149 |
| SRC | -8148 |
| APRT | -8130 |
| FCER1G | -8128 |
| C2 | -8124 |
| IGLV1-40 | -8088 |
| POLR3H | -8087 |
| ALDOC | -8085 |
| C1QA | -8083 |
| CD55 | -8080 |
| CSNK2B | -8078 |
| SIGLEC5 | -8058 |
| FCGR3A | -8055 |
| LILRB3 | -8035 |
| CXCL1 | -8034 |
| NLRX1 | -8024 |
| MYD88 | -8007 |
| GALNS | -7969 |
| CD209 | -7967 |
| TRAPPC1 | -7966 |
| PSAP | -7953 |
| KCNAB2 | -7943 |
| CAPN1 | -7920 |
| TXNDC5 | -7914 |
| DDOST | -7902 |
| CTSD | -7893 |
| POLR2E | -7886 |
| LIMK1 | -7870 |
| CANT1 | -7866 |
| BAIAP2 | -7839 |
| FTL | -7828 |
| VAV1 | -7822 |
| ITGAM | -7806 |
| DBNL | -7804 |
| RASGRP4 | -7795 |
| IMPDH1 | -7786 |
| ALOX5 | -7785 |
| TRIM32 | -7764 |
| CARD9 | -7716 |
| PSMB10 | -7709 |
| MAP2K7 | -7697 |
| RNASET2 | -7680 |
| GSTP1 | -7676 |
| TMEM179B | -7675 |
| MVP | -7640 |
| APEH | -7616 |
| CD300A | -7613 |
| ARPC1B | -7593 |
| CTSZ | -7584 |
| METTL7A | -7577 |
| PSMB5 | -7576 |
| MUC4 | -7552 |
| UBE2M | -7541 |
| DNM1 | -7539 |
| CNPY3 | -7536 |
| VAMP8 | -7535 |
| GM2A | -7520 |
| DNASE1L1 | -7509 |
| CD53 | -7506 |
| FADD | -7501 |
| PKM | -7496 |
| CD63 | -7486 |
| VAT1 | -7456 |
| ARSA | -7432 |
| GUSB | -7411 |
| IGKV3-15 | -7403 |
| IKBKG | -7367 |
| RAB3D | -7358 |
| LAMTOR1 | -7337 |
| TREM2 | -7286 |
| PSME3 | -7280 |
| PSMB2 | -7268 |
| PRG2 | -7266 |
| AAMP | -7244 |
| NKIRAS2 | -7217 |
| GRB2 | -7191 |
| WASF2 | -7177 |
| CFL1 | -7166 |
| SLC2A5 | -7149 |
| LCK | -7148 |
| C4A | -7134 |
| ANXA2 | -7132 |
| CST3 | -7129 |
| NDUFC2 | -7108 |
| PSMD2 | -7104 |
| PGM1 | -7071 |
| LGMN | -7062 |
| ATP6V0E1 | -7030 |
| HMOX2 | -7026 |
| ACLY | -7023 |
| PFKL | -7021 |
| IGHV3-11 | -7017 |
| SIGLEC9 | -7013 |
| PYCARD | -7010 |
| MIF | -7006 |
| CR2 | -6990 |
| MPO | -6977 |
| PPP2R1A | -6964 |
| CD33 | -6926 |
| NCKIPSD | -6918 |
| PRKCD | -6909 |
| UBA52 | -6880 |
| CYSTM1 | -6875 |
| AZU1 | -6868 |
| TCIRG1 | -6863 |
| RAC2 | -6835 |
| SNAP29 | -6830 |
| MYO9B | -6808 |
| EPX | -6806 |
| S100A1 | -6798 |
| PRDX4 | -6797 |
| SIRPA | -6788 |
| ENPP4 | -6759 |
| RHOA | -6754 |
| ARPC4 | -6731 |
| MAVS | -6723 |
| PSMB6 | -6709 |
| FUCA1 | -6706 |
| RAB5C | -6693 |
| ISG15 | -6682 |
| PYGB | -6678 |
| RPS6KA1 | -6676 |
| TREX1 | -6675 |
| MYH2 | -6671 |
| HSPA8 | -6665 |
| DNAJC5 | -6663 |
| PSMB3 | -6647 |
| LAMTOR2 | -6641 |
| LAT2 | -6615 |
| BTK | -6612 |
| AP1M1 | -6596 |
| PIK3R1 | -6564 |
| C3AR1 | -6548 |
| PTPRN2 | -6546 |
| PDZD11 | -6539 |
| NFAM1 | -6523 |
| PPIA | -6508 |
| DYNLL1 | -6465 |
| C7 | -6464 |
| FTH1 | -6455 |
| PSMD4 | -6452 |
| NCF4 | -6412 |
| ATP6V0B | -6404 |
| RAB5B | -6400 |
| AOC1 | -6397 |
| BRI3 | -6394 |
| PRTN3 | -6386 |
| MUC6 | -6359 |
| LY86 | -6355 |
| TAB1 | -6350 |
| PSMF1 | -6332 |
| MAPK3 | -6329 |
| PSEN1 | -6281 |
| ATP6V0A1 | -6280 |
| PDAP1 | -6258 |
| OTUD5 | -6256 |
| GPI | -6235 |
| TUBB4B | -6218 |
| SYK | -6217 |
| IGF2R | -6196 |
| UBB | -6193 |
| CD14 | -6153 |
| BRK1 | -6144 |
| PSMC5 | -6143 |
| AP2A2 | -6118 |
| ATP6V0D1 | -6117 |
| RNF216 | -6107 |
| P2RX1 | -6092 |
| PSMA7 | -6082 |
| PA2G4 | -6056 |
| ACTR1B | -6022 |
| PGAM1 | -6006 |
| TXNIP | -5982 |
| HVCN1 | -5979 |
| LGALS3 | -5963 |
| PSMB7 | -5953 |
| MYO1C | -5948 |
| TIMP2 | -5932 |
| TLR5 | -5906 |
| RAB37 | -5902 |
| TRPM2 | -5896 |
| MASP2 | -5892 |
| NCKAP1L | -5878 |
| ELK1 | -5875 |
| NOS2 | -5871 |
| PSMC4 | -5866 |
| RAB7A | -5854 |
| GAB2 | -5845 |
| TLR2 | -5828 |
| ARPC3 | -5798 |
| PPP2R5D | -5791 |
| CFD | -5789 |
| STBD1 | -5764 |
| RHOF | -5736 |
| PSMC3 | -5726 |
| ELMO2 | -5690 |
| PTGES2 | -5671 |
| UBR4 | -5637 |
| TRIM21 | -5612 |
| PDXK | -5585 |
| VRK3 | -5547 |
| VCP | -5509 |
| ITPR3 | -5506 |
| NPC2 | -5501 |
| PSMB1 | -5473 |
| DIAPH1 | -5472 |
| UNC13D | -5470 |
| NOD2 | -5469 |
| HEXB | -5455 |
| MLEC | -5382 |
| FAF2 | -5362 |
| CTSS | -5358 |
| CLEC4A | -5346 |
| SLC15A4 | -5316 |
| ACAA1 | -5304 |
| PRKCSH | -5301 |
| PRDX6 | -5286 |
| POLR3GL | -5285 |
| CD44 | -5281 |
| ATOX1 | -5254 |
| COTL1 | -5238 |
| APP | -5231 |
| LCP2 | -5202 |
| UBE2L6 | -5197 |
| PSMB4 | -5168 |
| XRCC6 | -5145 |
| OLR1 | -5138 |
| DOCK2 | -5130 |
| NFKBIB | -5076 |
| ACTB | -5073 |
| POLR2L | -5071 |
| SERPING1 | -5070 |
| NME2 | -5012 |
| TIFA | -4991 |
| CTSL | -4981 |
| AMPD3 | -4970 |
| HRAS | -4955 |
| CFP | -4887 |
| GLIPR1 | -4882 |
| FYN | -4854 |
| QSOX1 | -4847 |
| AGPAT2 | -4846 |
| GNS | -4788 |
| CPNE1 | -4785 |
| NEU1 | -4756 |
| FCGR2A | -4754 |
| ARPC1A | -4752 |
| SERPINB6 | -4751 |
| P2RX7 | -4748 |
| MASP1 | -4746 |
| VPS35L | -4738 |
| SKP1 | -4737 |
| C5AR2 | -4710 |
| DEFA4 | -4707 |
| IGKV1-33 | -4702 |
| ARPC2 | -4697 |
| MAP2K1 | -4692 |
| BPI | -4682 |
| LTF | -4657 |
| PSMD9 | -4655 |
| NF2 | -4649 |
| DDX41 | -4633 |
| TOM1 | -4624 |
| POLR3K | -4605 |
| ARL8A | -4561 |
| ATP6V1G1 | -4500 |
| LTA4H | -4460 |
| HUWE1 | -4455 |
| ECSIT | -4451 |
| ATP6V1D | -4357 |
| DYNC1H1 | -4355 |
| HSP90B1 | -4345 |
| TLR9 | -4319 |
| TRAF2 | -4296 |
| PLPP5 | -4285 |
| PLAUR | -4209 |
| TICAM2 | -4199 |
| PLD4 | -4193 |
| PSMC2 | -4179 |
| GSN | -4173 |
| POLR3D | -4118 |
| LAT | -4104 |
| STK11IP | -4103 |
| C4B | -4099 |
| RELA | -4097 |
| PSTPIP1 | -4077 |
| PKP1 | -4076 |
| IKBKE | -4068 |
| DEFA1 | -4036 |
| SERPINB1 | -4033 |
| SARM1 | -4011 |
| GYG1 | -3994 |
| NLRC4 | -3965 |
| CAP1 | -3949 |
| PRKACB | -3946 |
| TANK | -3918 |
| MANBA | -3901 |
| DNM2 | -3899 |
| ACP3 | -3897 |
| AGA | -3893 |
| POLR2F | -3890 |
| CDA | -3870 |
| CYBB | -3854 |
| PSMD10 | -3849 |
| TKFC | -3846 |
| OSTF1 | -3768 |
| GSDME | -3760 |
| NLRC3 | -3735 |
| FGL2 | -3730 |
| BIN2 | -3707 |
| TLR3 | -3698 |
| BTRC | -3694 |
| HLA-A | -3688 |
| MAGT1 | -3673 |
| RAP2B | -3635 |
| PELI3 | -3632 |
| JUP | -3580 |
| RAF1 | -3561 |
| CCR2 | -3535 |
| IQGAP2 | -3492 |
| TRAF3 | -3366 |
| TMC6 | -3356 |
| RAC1 | -3331 |
| ASAH1 | -3322 |
| PPIE | -3321 |
| PLD1 | -3314 |
| PAK1 | -3309 |
| CD19 | -3284 |
| LPCAT1 | -3282 |
| POLR2K | -3261 |
| CAMP | -3260 |
| IDH1 | -3258 |
| PSMA6 | -3225 |
| CDC42 | -3206 |
| ATP6AP2 | -3183 |
| ATP6V1E1 | -3137 |
| LY96 | -3104 |
| TXK | -3035 |
| PSME1 | -3031 |
| TXN | -3012 |
| KCMF1 | -2999 |
| PTPRJ | -2991 |
| RAB44 | -2971 |
| TRIM4 | -2969 |
| LAMP2 | -2955 |
| C1R | -2949 |
| FCGR1A | -2944 |
| LYN | -2889 |
| SRP14 | -2850 |
| CRCP | -2833 |
| CREBBP | -2822 |
| CASP9 | -2821 |
| ELMO1 | -2743 |
| ARSB | -2736 |
| UBE2D2 | -2735 |
| PSMD7 | -2731 |
| CR1 | -2725 |
| EEF2 | -2697 |
| AGL | -2689 |
| WIPF2 | -2680 |
| PSMA5 | -2649 |
| ATP6V1B2 | -2647 |
| ITGAX | -2635 |
| MMP9 | -2629 |
| PSMC1 | -2604 |
| STAT6 | -2573 |
| SIGIRR | -2572 |
| RASGRP2 | -2558 |
| CYFIP2 | -2546 |
| S100A8 | -2515 |
| C5AR1 | -2504 |
| ITGAV | -2473 |
| GZMM | -2461 |
| ADAM8 | -2446 |
| FBXW11 | -2408 |
| C6orf120 | -2385 |
| POLR3C | -2369 |
| PPP2CB | -2329 |
| HGSNAT | -2328 |
| IST1 | -2289 |
| POLR3A | -2280 |
| UBA7 | -2276 |
| IRF3 | -2274 |
| TLR4 | -2238 |
| PTAFR | -2233 |
| SIGLEC15 | -2223 |
| TNIP2 | -2170 |
| POLR2H | -2169 |
| PCBP2 | -2168 |
| PTPRC | -2154 |
| PSMD14 | -2133 |
| CLEC7A | -2119 |
| MAP3K14 | -1995 |
| B2M | -1976 |
| RIPK1 | -1922 |
| SYNGR1 | -1890 |
| DGAT1 | -1889 |
| NFATC3 | -1875 |
| ATAD3B | -1816 |
| HPSE | -1810 |
| CAB39 | -1802 |
| PSMD1 | -1782 |
| DEGS1 | -1772 |
| LAMTOR3 | -1758 |
| PSMA4 | -1756 |
| ELANE | -1741 |
| AGER | -1738 |
| MAP2K3 | -1696 |
| CYFIP1 | -1658 |
| IMPDH2 | -1641 |
| TIRAP | -1629 |
| ABL1 | -1625 |
| EEF1A1 | -1605 |
| PSME2 | -1591 |
| TLR8 | -1571 |
| GDI2 | -1535 |
| RAB9B | -1509 |
| C1S | -1499 |
| PSMD11 | -1483 |
| SPTAN1 | -1454 |
| CFI | -1444 |
| PSMD5 | -1433 |
| RAB10 | -1385 |
| MUC1 | -1357 |
| NCF2 | -1349 |
| TOMM70 | -1316 |
| CTSH | -1301 |
| PSMA2 | -1286 |
| MAPK14 | -1200 |
| CTSC | -1185 |
| ILF2 | -1166 |
| ATP6V0A2 | -1143 |
| ERP44 | -1134 |
| CFH | -1103 |
| PGRMC1 | -1094 |
| DHX9 | -1082 |
| MUC12 | -1066 |
| CREG1 | -1028 |
| IQGAP1 | -1025 |
| ARHGAP9 | -1009 |
| STK10 | -977 |
| ARPC5 | -969 |
| ACTG1 | -959 |
| CARD11 | -915 |
| COPB1 | -893 |
| ALAD | -888 |
| LCN2 | -875 |
| PROS1 | -863 |
| VAV2 | -840 |
| CD247 | -834 |
| HLA-H | -815 |
| RASGRP1 | -813 |
| ADAM10 | -804 |
| CDC34 | -803 |
| CAPZA2 | -802 |
| PPP3CB | -797 |
| PSMD13 | -754 |
| YPEL5 | -739 |
| B4GALT1 | -661 |
| PIK3R4 | -607 |
| RAB31 | -572 |
| TLR1 | -517 |
| AHCYL1 | -485 |
| NFATC1 | -480 |
| RBSN | -469 |
| CPNE3 | -465 |
| COLEC11 | -449 |
| UBE2K | -426 |
| POLR3B | -417 |
| ACTR10 | -373 |
| DHX58 | -345 |
| TMEM63A | -321 |
| CTSG | -319 |
| CRACR2A | -287 |
| EP300 | -244 |
| PSMB8 | -235 |
| CDK13 | -219 |
| XRCC5 | -190 |
| DUSP7 | -150 |
| CMTM6 | -131 |
| PRKDC | -116 |
| RAP1A | -109 |
| PIK3CB | -106 |
| TBC1D10C | -97 |
| CASP2 | -84 |
| CD300LB | -68 |
| CCR6 | -53 |
| PSME4 | -48 |
| CCT2 | -39 |
| WIPF1 | 21 |
| PSMD6 | 26 |
| PYGL | 29 |
| PDPK1 | 33 |
| DEFA3 | 43 |
| ATP8A1 | 145 |
| CD58 | 163 |
| TAX1BP1 | 167 |
| NFKBIA | 181 |
| POLR1C | 223 |
| RPS27A | 229 |
| ATP11A | 281 |
| ATP6V1G2 | 311 |
| TLR6 | 378 |
| PSMA1 | 379 |
| MYO5A | 391 |
| TICAM1 | 465 |
| FRMPD3 | 485 |
| DYNLT1 | 501 |
| NFKB1 | 503 |
| POLR3E | 523 |
| TEC | 533 |
| C5 | 536 |
| NHLRC3 | 550 |
| SAA1 | 558 |
| CPPED1 | 613 |
| C4BPB | 614 |
| CLEC5A | 625 |
| NCK1 | 629 |
| GOLGA7 | 702 |
| MGST1 | 767 |
| MAP2K4 | 772 |
| RAB4B | 790 |
| MAPK13 | 792 |
| RAP1B | 813 |
| POLR1D | 855 |
| PPP3CA | 858 |
| RAB18 | 879 |
| ATP6V1H | 924 |
| MAPKAPK2 | 933 |
| DERA | 944 |
| EEA1 | 975 |
| ACTR2 | 1000 |
| CASP1 | 1004 |
| COMMD3 | 1045 |
| STING1 | 1130 |
| BST1 | 1165 |
| SOCS1 | 1191 |
| TRIM56 | 1246 |
| MAP3K7 | 1306 |
| POLR3G | 1321 |
| DNAJC3 | 1382 |
| CUL1 | 1406 |
| HSP90AB1 | 1424 |
| ICAM3 | 1443 |
| PLA2G2A | 1477 |
| PRCP | 1478 |
| S100A9 | 1503 |
| PAFAH1B2 | 1516 |
| CD47 | 1536 |
| ICAM2 | 1582 |
| MAPK1 | 1610 |
| CALM1 | 1638 |
| CAPZA1 | 1732 |
| UBE2N | 1734 |
| NRAS | 1742 |
| PAK3 | 1749 |
| IKBKB | 1755 |
| GRAP2 | 1775 |
| ITGAL | 1798 |
| TAB2 | 1818 |
| ATP11B | 1882 |
| RAB14 | 1901 |
| MME | 1917 |
| RAB24 | 1920 |
| VAV3 | 1970 |
| CRK | 1993 |
| SCAMP1 | 2005 |
| TNFAIP6 | 2017 |
| ATP6V1A | 2025 |
| MMP8 | 2043 |
| IRF7 | 2060 |
| RAB6A | 2072 |
| NAPRT | 2077 |
| PIK3CA | 2176 |
| FPR1 | 2178 |
| ATP8B4 | 2193 |
| ATG5 | 2233 |
| TSPAN14 | 2269 |
| UBE2V1 | 2277 |
| PLD2 | 2287 |
| NCKAP1 | 2330 |
| GSDMD | 2372 |
| KPNB1 | 2425 |
| MAPK9 | 2439 |
| RPS6KA2 | 2440 |
| CD300E | 2454 |
| CHUK | 2486 |
| VTN | 2494 |
| SUGT1 | 2512 |
| PAK2 | 2552 |
| POLR3F | 2553 |
| DNAJC13 | 2644 |
| CYLD | 2838 |
| IFIH1 | 2853 |
| ATP6V1C1 | 2865 |
| TNFRSF1B | 2872 |
| TLR7 | 2925 |
| WASF3 | 2959 |
| GLA | 2965 |
| C3 | 2977 |
| CCT8 | 3002 |
| TMEM30A | 3034 |
| BCL2 | 3041 |
| MEF2A | 3106 |
| ATP6V1E2 | 3118 |
| C6 | 3124 |
| GMFG | 3137 |
| ATF1 | 3170 |
| NLRP1 | 3172 |
| DUSP6 | 3235 |
| UBC | 3246 |
| MAPK12 | 3258 |
| BST2 | 3310 |
| CFHR3 | 3314 |
| ABI2 | 3335 |
| ACTR3 | 3346 |
| CREB1 | 3370 |
| ANO6 | 3372 |
| CHI3L1 | 3386 |
| ATP6V0D2 | 3413 |
| UBA3 | 3420 |
| VAPA | 3437 |
| PIK3C3 | 3477 |
| NIT2 | 3498 |
| CASP8 | 3510 |
| PPP2CA | 3519 |
| ATP7A | 3594 |
| SVIP | 3595 |
| MAP3K1 | 3619 |
| CAT | 3646 |
| PSMD12 | 3658 |
| BIRC2 | 3674 |
| PTX3 | 3686 |
| HSP90AA1 | 3693 |
| DSN1 | 3697 |
| HEBP2 | 3703 |
| PTPN11 | 3742 |
| UBE2D3 | 3753 |
| PSMC6 | 3801 |
| DHX36 | 3817 |
| SLC44A2 | 3834 |
| NLRP3 | 3857 |
| ROCK1 | 3867 |
| RPS6KA3 | 3890 |
| KRAS | 3903 |
| PADI2 | 3928 |
| ATF2 | 3946 |
| CEACAM3 | 3957 |
| NFASC | 3959 |
| NFATC2 | 3997 |
| ITPR2 | 4036 |
| IRAK3 | 4043 |
| ABI1 | 4070 |
| PRKCQ | 4076 |
| CAND1 | 4089 |
| PSMB9 | 4121 |
| PLAU | 4122 |
| DUSP3 | 4149 |
| TAB3 | 4183 |
| HMOX1 | 4200 |
| MYH9 | 4253 |
| CD3G | 4272 |
| CFHR1 | 4275 |
| NBEAL2 | 4305 |
| SHC1 | 4317 |
| PPBP | 4468 |
| MOSPD2 | 4491 |
| AIM2 | 4492 |
| NFKB2 | 4495 |
| ATG12 | 4504 |
| CD46 | 4669 |
| HLA-E | 4804 |
| PTPN4 | 4832 |
| HLA-B | 4836 |
| WASL | 4892 |
| MCEMP1 | 4906 |
| SLPI | 4921 |
| SERPINA3 | 4964 |
| MAP3K8 | 4967 |
| KLRK1 | 5011 |
| QPCT | 5017 |
| CASP4 | 5033 |
| PSMA3 | 5077 |
| RAP2C | 5100 |
| HP | 5104 |
| LEAP2 | 5123 |
| PLA2G6 | 5139 |
| SNAP23 | 5187 |
| PLAC8 | 5241 |
| LBP | 5292 |
| HMGB1 | 5302 |
| ARMC8 | 5310 |
| RELB | 5322 |
| RAB27A | 5323 |
| SEM1 | 5372 |
| OLFM4 | 5408 |
| UBE2D1 | 5427 |
| PANX1 | 5438 |
| SOS1 | 5452 |
| IRAK4 | 5507 |
| RAB3A | 5550 |
| MAPK8 | 5565 |
| PPP3R1 | 5668 |
| CNN2 | 5684 |
| SIKE1 | 5687 |
| PGM2 | 5693 |
| CEP290 | 5713 |
| CTNNB1 | 5757 |
| ITCH | 5770 |
| CTSK | 5776 |
| HBB | 5795 |
| PLCG1 | 5830 |
| WASF1 | 5834 |
| PGLYRP1 | 5847 |
| ITK | 5899 |
| DOCK1 | 5903 |
| FCN3 | 5904 |
| IRAG2 | 5941 |
| SELL | 5962 |
| CD59 | 6004 |
| BIRC3 | 6018 |
| PNP | 6038 |
| DTX4 | 6069 |
| ATP6V1B1 | 6096 |
| MAP2K6 | 6128 |
| DUSP4 | 6239 |
| CHIT1 | 6264 |
| PLEKHO2 | 6266 |
| DYNC1LI1 | 6270 |
| CEACAM1 | 6329 |
| GGH | 6348 |
| WIPF3 | 6386 |
| NOS3 | 6496 |
| NOD1 | 6632 |
| ALPK1 | 6672 |
| IFI16 | 6685 |
| MYO10 | 6688 |
| MALT1 | 6698 |
| CLEC10A | 6727 |
| PRKCE | 6762 |
| MRE11 | 6908 |
| YES1 | 6926 |
| TRIM25 | 6947 |
| VNN1 | 6989 |
| ATP6V1C2 | 7031 |
| NKIRAS1 | 7084 |
| DEFB124 | 7136 |
| TBK1 | 7169 |
| TRAF6 | 7237 |
| VCL | 7281 |
| KLRD1 | 7367 |
| SNAP25 | 7382 |
| GCA | 7447 |
| LRRFIP1 | 7451 |
| FRK | 7510 |
| SDCBP | 7519 |
| CLEC12A | 7549 |
| RIPK3 | 7603 |
| ZBP1 | 7679 |
| FPR2 | 7694 |
| DDX58 | 7734 |
| HLA-C | 7759 |
| FCN1 | 7955 |
| TNFAIP3 | 8015 |
| DDX3X | 8042 |
| MEF2C | 8059 |
| PTK2 | 8088 |
| BCL10 | 8277 |
| CLEC4E | 8310 |
| IRAK2 | 8355 |
| ADGRE3 | 8356 |
| NLRC5 | 8445 |
| PPP2R1B | 8460 |
| FOS | 8474 |
| RPS6KA5 | 8492 |
| CGAS | 8561 |
| RNF125 | 8568 |
| CPN2 | 8591 |
| CD36 | 8666 |
| FCER1A | 8672 |
| PELI2 | 8729 |
| MNDA | 8733 |
| NOS1 | 8768 |
| S100A12 | 8800 |
| CTSV | 8815 |
| HSPA6 | 8872 |
| HSPA1B | 8917 |
| MEFV | 8931 |
| RIPK2 | 8936 |
| GNLY | 8967 |
| FCAR | 8968 |
| PLCG2 | 8985 |
| LRG1 | 9040 |
| A1BG | 9149 |
| STOM | 9231 |
| FABP5 | 9265 |
| S100P | 9326 |
| MAPK11 | 9361 |
| HTN1 | 9362 |
| APAF1 | 9365 |
| LRRC7 | 9375 |
| IL1B | 9376 |
| ITPR1 | 9487 |
| CASP10 | 9558 |
| PECAM1 | 9560 |
| JUN | 9573 |
| CRISPLD2 | 9598 |
| MUC3A | 9677 |
| MAPK10 | 9718 |
| DNM3 | 9866 |
| HERC5 | 9894 |
| CD93 | 9927 |
| MGAM | 9981 |
| HSPA1A | 9988 |
| MMP25 | 10087 |
| DSP | 10097 |
| PTPRB | 10103 |
| CXCR2 | 10117 |
| ADGRG3 | 10123 |
| CXCR1 | 10135 |
| PELI1 | 10144 |
| FCGR3B | 10145 |
| SLC2A3 | 10153 |
Metabolism of proteins
| 678 | |
|---|---|
| set | Metabolism of proteins |
| setSize | 1695 |
| pANOVA | 7.22e-32 |
| s.dist | -0.172 |
| p.adjustANOVA | 3.49e-29 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| MUC20 | -9146 |
| PENK | -9122 |
| CES1 | -9105 |
| RTN4RL1 | -9073 |
| ADAMTSL5 | -9072 |
| MELTF | -9059 |
| ALG3 | -9024 |
| B3GNT9 | -8999 |
| GALNT10 | -8989 |
| IGFBP1 | -8984 |
| COPZ2 | -8971 |
| RPS26 | -8966 |
| SERPINA1 | -8963 |
| LTBP1 | -8961 |
| KDELR1 | -8946 |
| CSF2RA | -8945 |
| RPA1 | -8931 |
| COPS7A | -8927 |
| SBSPON | -8920 |
| CKAP4 | -8916 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MUC20 | -9146.0 |
| PENK | -9122.0 |
| CES1 | -9105.0 |
| RTN4RL1 | -9073.0 |
| ADAMTSL5 | -9072.0 |
| MELTF | -9059.0 |
| ALG3 | -9024.0 |
| B3GNT9 | -8999.0 |
| GALNT10 | -8989.0 |
| IGFBP1 | -8984.0 |
| COPZ2 | -8971.0 |
| RPS26 | -8966.0 |
| SERPINA1 | -8963.0 |
| LTBP1 | -8961.0 |
| KDELR1 | -8946.0 |
| CSF2RA | -8945.0 |
| RPA1 | -8931.0 |
| COPS7A | -8927.0 |
| SBSPON | -8920.0 |
| CKAP4 | -8916.0 |
| UAP1 | -8907.0 |
| BMP4 | -8893.0 |
| KDELR3 | -8886.0 |
| DPM2 | -8879.0 |
| SLC35C1 | -8876.0 |
| CTSA | -8873.0 |
| SEMA5A | -8863.0 |
| DOLK | -8850.0 |
| BET1L | -8849.0 |
| ST6GALNAC4 | -8835.0 |
| DAG1 | -8830.0 |
| NCSTN | -8815.0 |
| P4HB | -8801.0 |
| MRPS6 | -8791.0 |
| TIMP1 | -8781.0 |
| PMM2 | -8777.0 |
| MRPL38 | -8772.0 |
| FN1 | -8771.0 |
| LY6D | -8763.0 |
| NANS | -8733.0 |
| TMEM115 | -8729.0 |
| NUP210 | -8727.0 |
| MRPS34 | -8726.0 |
| APLP2 | -8697.0 |
| RNF135 | -8690.0 |
| ST6GALNAC6 | -8684.0 |
| ASB13 | -8677.0 |
| RAB1B | -8672.0 |
| APOB | -8671.0 |
| ABCA3 | -8664.0 |
| SEC13 | -8653.0 |
| ERAL1 | -8635.0 |
| COPG1 | -8633.0 |
| MEN1 | -8631.0 |
| GMPPB | -8623.0 |
| PIGT | -8609.0 |
| DHDDS | -8593.0 |
| FBXW5 | -8591.0 |
| THSD4 | -8579.0 |
| GNB2 | -8571.0 |
| B4GAT1 | -8568.0 |
| YKT6 | -8548.0 |
| TMED3 | -8546.0 |
| PEX10 | -8545.0 |
| RGS6 | -8538.0 |
| TMED9 | -8530.0 |
| ANPEP | -8527.0 |
| JOSD2 | -8510.0 |
| UCHL1 | -8502.0 |
| MRPS24 | -8489.0 |
| COG8 | -8475.0 |
| GBA | -8462.0 |
| COMMD9 | -8460.0 |
| NCOR2 | -8458.0 |
| TTLL12 | -8454.0 |
| MRPL57 | -8452.0 |
| MRPL41 | -8451.0 |
| MRPL4 | -8434.0 |
| PIGQ | -8426.0 |
| MRPL12 | -8422.0 |
| PSENEN | -8409.0 |
| CPA3 | -8404.0 |
| MCRS1 | -8402.0 |
| RPN2 | -8394.0 |
| ANK3 | -8387.0 |
| COPE | -8360.0 |
| ADAMTS15 | -8355.0 |
| AURKAIP1 | -8335.0 |
| PSMD3 | -8328.0 |
| MUL1 | -8318.0 |
| B4GALT2 | -8317.0 |
| ARF3 | -8293.0 |
| ADAMTS5 | -8283.0 |
| TGFB1 | -8281.0 |
| TSFM | -8273.0 |
| FN3KRP | -8270.0 |
| FAM20C | -8253.0 |
| FUCA2 | -8249.0 |
| STX5 | -8241.0 |
| ADAMTS17 | -8231.0 |
| MRPL10 | -8223.0 |
| GANAB | -8218.0 |
| TBCB | -8204.0 |
| RAB36 | -8202.0 |
| ALG12 | -8201.0 |
| GLB1 | -8189.0 |
| GALNT5 | -8187.0 |
| LYZ | -8186.0 |
| LY6K | -8165.0 |
| ETFB | -8156.0 |
| DCTN1 | -8155.0 |
| WARS1 | -8152.0 |
| MPDU1 | -8150.0 |
| PSMD8 | -8149.0 |
| DPH2 | -8106.0 |
| POMGNT2 | -8105.0 |
| DCAF11 | -8082.0 |
| CD55 | -8080.0 |
| CSNK2B | -8078.0 |
| MRPL34 | -8071.0 |
| MRPL43 | -8060.0 |
| SEC61A1 | -8056.0 |
| MRPL2 | -8039.0 |
| RPS4X | -8028.0 |
| VARS1 | -8026.0 |
| GPAA1 | -8025.0 |
| ALG1 | -8022.0 |
| EIF4G1 | -8010.0 |
| SPTBN4 | -8000.0 |
| TADA3 | -7998.0 |
| UBD | -7988.0 |
| NEURL2 | -7982.0 |
| SUMF2 | -7981.0 |
| UCHL3 | -7978.0 |
| COPZ1 | -7972.0 |
| TRAPPC1 | -7966.0 |
| MRPL16 | -7965.0 |
| RNF181 | -7961.0 |
| DOLPP1 | -7956.0 |
| APH1A | -7954.0 |
| SSR4 | -7948.0 |
| LMAN2 | -7933.0 |
| AMFR | -7926.0 |
| ADAMTSL3 | -7925.0 |
| TSPAN15 | -7917.0 |
| SRPRB | -7913.0 |
| ARL2 | -7910.0 |
| C1GALT1 | -7908.0 |
| DDOST | -7902.0 |
| KDELR2 | -7899.0 |
| POM121C | -7894.0 |
| CTSD | -7893.0 |
| POMC | -7890.0 |
| EEF2KMT | -7874.0 |
| MGAT1 | -7872.0 |
| USP5 | -7869.0 |
| SUMF1 | -7868.0 |
| DAD1 | -7820.0 |
| KEAP1 | -7807.0 |
| STX1A | -7794.0 |
| MRPS16 | -7777.0 |
| GOLGA2 | -7775.0 |
| RXRA | -7774.0 |
| TPR | -7773.0 |
| SPCS1 | -7772.0 |
| SRPRA | -7771.0 |
| GPS1 | -7769.0 |
| PDIA3 | -7754.0 |
| PFDN1 | -7742.0 |
| OTUB1 | -7741.0 |
| BTBD6 | -7737.0 |
| ARF1 | -7717.0 |
| PSMB10 | -7709.0 |
| DCTN3 | -7698.0 |
| FOLR2 | -7688.0 |
| ADAMTSL4 | -7685.0 |
| ST6GALNAC5 | -7660.0 |
| SYVN1 | -7632.0 |
| FKBP8 | -7629.0 |
| PARS2 | -7627.0 |
| RAD23A | -7624.0 |
| APEH | -7616.0 |
| RENBP | -7615.0 |
| ASB1 | -7607.0 |
| TUBA1C | -7604.0 |
| PNPLA2 | -7596.0 |
| GSPT2 | -7587.0 |
| GALNT2 | -7585.0 |
| CTSZ | -7584.0 |
| SEC16A | -7580.0 |
| PPP6R1 | -7578.0 |
| PSMB5 | -7576.0 |
| TMEM129 | -7565.0 |
| USP19 | -7559.0 |
| MUC4 | -7552.0 |
| PFDN6 | -7550.0 |
| RPN1 | -7545.0 |
| TUBA1B | -7542.0 |
| UBE2M | -7541.0 |
| GFPT2 | -7530.0 |
| CUL7 | -7521.0 |
| DDB1 | -7515.0 |
| ASB11 | -7514.0 |
| NEDD8 | -7504.0 |
| UBA1 | -7503.0 |
| TRAPPC5 | -7491.0 |
| MOGS | -7465.0 |
| COPS6 | -7464.0 |
| SUMO3 | -7463.0 |
| TTLL1 | -7460.0 |
| WDTC1 | -7452.0 |
| ARSA | -7432.0 |
| MRPL20 | -7416.0 |
| UBE2J2 | -7410.0 |
| DCTN5 | -7397.0 |
| GMPPA | -7395.0 |
| MRPL23 | -7387.0 |
| ARFGAP1 | -7381.0 |
| L3MBTL2 | -7374.0 |
| PIGS | -7370.0 |
| EIF3B | -7368.0 |
| IKBKG | -7367.0 |
| RAB3D | -7358.0 |
| MRPS18A | -7353.0 |
| CD52 | -7342.0 |
| LRRC41 | -7324.0 |
| DCTN2 | -7295.0 |
| STT3A | -7290.0 |
| PSME3 | -7280.0 |
| PSMB2 | -7268.0 |
| GALNT15 | -7260.0 |
| LEP | -7248.0 |
| VARS2 | -7239.0 |
| TRMT112 | -7235.0 |
| GNG5 | -7218.0 |
| CCT3 | -7207.0 |
| EDEM2 | -7195.0 |
| OS9 | -7193.0 |
| CDKN2A | -7189.0 |
| NUP62 | -7186.0 |
| CAPZB | -7174.0 |
| GFUS | -7164.0 |
| ADAMTSL2 | -7159.0 |
| F7 | -7142.0 |
| GGCX | -7137.0 |
| C4A | -7134.0 |
| CST3 | -7129.0 |
| DDA1 | -7113.0 |
| MRPS7 | -7107.0 |
| PSMD2 | -7104.0 |
| UBE2I | -7091.0 |
| RABGGTA | -7090.0 |
| TRIM27 | -7087.0 |
| PMM1 | -7072.0 |
| PDIA6 | -7070.0 |
| SEC61B | -7068.0 |
| MRPS11 | -7057.0 |
| FARSA | -7055.0 |
| BABAM1 | -7037.0 |
| MRPS18B | -7020.0 |
| RAB11B | -7016.0 |
| APOE | -7009.0 |
| AAAS | -7005.0 |
| NR1H2 | -6960.0 |
| MGAT4B | -6946.0 |
| DCAF4 | -6938.0 |
| MRPL14 | -6937.0 |
| MRPS12 | -6931.0 |
| GALNT14 | -6930.0 |
| CTBP1 | -6915.0 |
| CCDC22 | -6893.0 |
| ADRM1 | -6891.0 |
| FFAR4 | -6885.0 |
| UBA52 | -6880.0 |
| PIGM | -6878.0 |
| INO80 | -6873.0 |
| GGA1 | -6867.0 |
| TMED2 | -6853.0 |
| COPA | -6837.0 |
| ADORA2B | -6827.0 |
| GNB1 | -6821.0 |
| ARRB2 | -6809.0 |
| MRTFA | -6807.0 |
| RHOA | -6754.0 |
| NUCB1 | -6738.0 |
| MRPL49 | -6736.0 |
| SRP68 | -6724.0 |
| MAVS | -6723.0 |
| RANGAP1 | -6714.0 |
| CETN2 | -6713.0 |
| PSMB6 | -6709.0 |
| FUCA1 | -6706.0 |
| RAB5C | -6693.0 |
| DYNLL2 | -6690.0 |
| CALR | -6689.0 |
| MRPL40 | -6680.0 |
| DPAGT1 | -6669.0 |
| HSPA8 | -6665.0 |
| ARF5 | -6661.0 |
| MRPL54 | -6656.0 |
| RNF5 | -6648.0 |
| PSMB3 | -6647.0 |
| MRPL22 | -6642.0 |
| FBXW9 | -6624.0 |
| MVD | -6623.0 |
| RAB42 | -6608.0 |
| ELOB | -6600.0 |
| RRAGA | -6599.0 |
| SLC17A5 | -6589.0 |
| FBXO2 | -6574.0 |
| EIF5A | -6573.0 |
| HDAC3 | -6566.0 |
| SEC11C | -6561.0 |
| RNF123 | -6560.0 |
| ARFGAP2 | -6556.0 |
| PARP1 | -6552.0 |
| COPG2 | -6550.0 |
| ADAMTS3 | -6521.0 |
| TRAPPC2L | -6498.0 |
| CHCHD1 | -6474.0 |
| CDH2 | -6470.0 |
| DYNLL1 | -6465.0 |
| PSMD4 | -6452.0 |
| DERL1 | -6431.0 |
| NUP88 | -6417.0 |
| CSF1 | -6415.0 |
| TPGS1 | -6410.0 |
| RAB5B | -6400.0 |
| HGS | -6399.0 |
| RPL26L1 | -6364.0 |
| MUC6 | -6359.0 |
| TAB1 | -6350.0 |
| ACTR1A | -6346.0 |
| MRPS2 | -6344.0 |
| PSMF1 | -6332.0 |
| LMAN2L | -6325.0 |
| GNA11 | -6316.0 |
| SELENOS | -6312.0 |
| FBXL15 | -6290.0 |
| GNG7 | -6266.0 |
| PARK7 | -6265.0 |
| RAB41 | -6262.0 |
| OTUD5 | -6256.0 |
| SEC61G | -6251.0 |
| ALG2 | -6248.0 |
| MRPL55 | -6245.0 |
| EXOC7 | -6237.0 |
| POM121 | -6233.0 |
| MRPL53 | -6232.0 |
| H2BC12 | -6223.0 |
| TUBB4B | -6218.0 |
| COMMD5 | -6211.0 |
| GOSR2 | -6207.0 |
| TNIP1 | -6201.0 |
| UBB | -6193.0 |
| VDAC1 | -6184.0 |
| PCSK1 | -6169.0 |
| QARS1 | -6159.0 |
| ST3GAL1 | -6158.0 |
| PIGF | -6157.0 |
| PIGV | -6155.0 |
| ENGASE | -6148.0 |
| PSMC5 | -6143.0 |
| PCMT1 | -6136.0 |
| RNF40 | -6134.0 |
| CHST8 | -6133.0 |
| NRN1L | -6115.0 |
| ADAMTS7 | -6113.0 |
| AIMP2 | -6102.0 |
| SEC24C | -6100.0 |
| TUFM | -6084.0 |
| PSMA7 | -6082.0 |
| EEF1A2 | -6060.0 |
| NAPSA | -6047.0 |
| MRPL24 | -6045.0 |
| SMAD3 | -6044.0 |
| MRPL17 | -6025.0 |
| GADD45GIP1 | -6013.0 |
| TP53 | -6010.0 |
| NR1H3 | -5984.0 |
| GNA15 | -5973.0 |
| USP20 | -5968.0 |
| RAB34 | -5960.0 |
| PSMB7 | -5953.0 |
| LGALS1 | -5938.0 |
| NAGK | -5927.0 |
| NAPA | -5914.0 |
| UBE2L3 | -5910.0 |
| MRPL9 | -5907.0 |
| SKIV2L | -5904.0 |
| RAB37 | -5902.0 |
| VAMP2 | -5893.0 |
| EIF2B2 | -5888.0 |
| PSMC4 | -5866.0 |
| FBXO44 | -5864.0 |
| TPST1 | -5860.0 |
| RAB7A | -5854.0 |
| ANK1 | -5844.0 |
| FSTL1 | -5807.0 |
| USP4 | -5800.0 |
| SPSB4 | -5797.0 |
| ACTR8 | -5784.0 |
| ADAMTS16 | -5780.0 |
| RAB40B | -5779.0 |
| RPL39L | -5767.0 |
| EIF4EBP1 | -5758.0 |
| MAN1B1 | -5730.0 |
| PPARA | -5728.0 |
| PSMC3 | -5726.0 |
| UBE2F | -5708.0 |
| MMP1 | -5699.0 |
| ARF4 | -5692.0 |
| MBTPS1 | -5686.0 |
| CHGB | -5684.0 |
| TRIM28 | -5673.0 |
| RAET1G | -5658.0 |
| SCG2 | -5652.0 |
| CP | -5647.0 |
| MDC1 | -5640.0 |
| SPSB2 | -5632.0 |
| MRPL27 | -5620.0 |
| MARS1 | -5603.0 |
| BAP1 | -5598.0 |
| MRPS23 | -5587.0 |
| MRPS17 | -5568.0 |
| POMGNT1 | -5565.0 |
| MRPL46 | -5557.0 |
| GBF1 | -5553.0 |
| ASB8 | -5552.0 |
| EXOC3 | -5549.0 |
| INCENP | -5541.0 |
| RAB8A | -5535.0 |
| TMED10 | -5519.0 |
| EIF2B1 | -5515.0 |
| VCP | -5509.0 |
| PSMB1 | -5473.0 |
| NOD2 | -5469.0 |
| RAB32 | -5463.0 |
| ARSG | -5459.0 |
| TBCC | -5443.0 |
| TRAPPC3 | -5420.0 |
| RAB7B | -5412.0 |
| USP11 | -5409.0 |
| MRPL37 | -5406.0 |
| MLEC | -5382.0 |
| TGOLN2 | -5360.0 |
| AXIN1 | -5355.0 |
| NUP93 | -5327.0 |
| PRKCSH | -5301.0 |
| MARS2 | -5291.0 |
| PIGO | -5284.0 |
| FOLR1 | -5272.0 |
| DCAF7 | -5246.0 |
| MRPL28 | -5240.0 |
| RPS14 | -5234.0 |
| APP | -5231.0 |
| MRPL3 | -5226.0 |
| PHC2 | -5219.0 |
| UBE2L6 | -5197.0 |
| EARS2 | -5192.0 |
| POMT2 | -5184.0 |
| CHST10 | -5170.0 |
| PSMB4 | -5168.0 |
| GZMH | -5161.0 |
| GALNT11 | -5160.0 |
| NUP37 | -5152.0 |
| AARS1 | -5139.0 |
| GGA3 | -5136.0 |
| WRAP53 | -5126.0 |
| ASB6 | -5125.0 |
| PEX2 | -5116.0 |
| FURIN | -5098.0 |
| EEF1A1P5 | -5078.0 |
| COL7A1 | -5075.0 |
| ACTB | -5073.0 |
| DAXX | -5069.0 |
| SEC22B | -5055.0 |
| UCN | -5039.0 |
| MPI | -5037.0 |
| KBTBD7 | -5035.0 |
| FBXL8 | -5033.0 |
| TRRAP | -5027.0 |
| PEX12 | -5023.0 |
| PTRH2 | -5005.0 |
| PREB | -4989.0 |
| WDR61 | -4919.0 |
| RPL27 | -4912.0 |
| RPL27A | -4896.0 |
| RAB40C | -4891.0 |
| CFP | -4887.0 |
| CBX5 | -4883.0 |
| UBE2Z | -4878.0 |
| PEX5 | -4860.0 |
| FBXO41 | -4858.0 |
| EIF4H | -4855.0 |
| EIF2B5 | -4853.0 |
| QSOX1 | -4847.0 |
| MRPL36 | -4842.0 |
| RNF185 | -4812.0 |
| IGF1 | -4800.0 |
| MRPS22 | -4795.0 |
| KLHL41 | -4791.0 |
| ADAMTS10 | -4774.0 |
| SDC2 | -4765.0 |
| ZBTB16 | -4763.0 |
| NEU1 | -4756.0 |
| MRPL13 | -4750.0 |
| UBE2E3 | -4749.0 |
| RPL35 | -4745.0 |
| NEU3 | -4741.0 |
| SKP1 | -4737.0 |
| LRR1 | -4728.0 |
| NUP188 | -4718.0 |
| VDAC2 | -4709.0 |
| AMDHD2 | -4690.0 |
| FUOM | -4679.0 |
| FBXL18 | -4675.0 |
| LY6E | -4670.0 |
| RING1 | -4669.0 |
| EIF3F | -4664.0 |
| LTF | -4657.0 |
| PSMD9 | -4655.0 |
| FAU | -4625.0 |
| TPST2 | -4585.0 |
| NSMCE1 | -4581.0 |
| NRIP1 | -4579.0 |
| KDM1B | -4575.0 |
| SSR3 | -4573.0 |
| TARS2 | -4572.0 |
| GNB3 | -4560.0 |
| MRPS27 | -4548.0 |
| MSRA | -4541.0 |
| MRPL15 | -4532.0 |
| HIPK2 | -4524.0 |
| MRPS21 | -4522.0 |
| NPL | -4519.0 |
| INO80E | -4502.0 |
| SHISA5 | -4501.0 |
| ANO8 | -4458.0 |
| RBX1 | -4435.0 |
| MRPS10 | -4427.0 |
| SEC31A | -4403.0 |
| DCTN6 | -4386.0 |
| TADA2B | -4382.0 |
| DYNC1H1 | -4355.0 |
| HSP90B1 | -4345.0 |
| TFG | -4337.0 |
| SEC22A | -4335.0 |
| COPB2 | -4312.0 |
| AGBL5 | -4299.0 |
| MRPL47 | -4298.0 |
| TRAF2 | -4296.0 |
| NSMCE3 | -4248.0 |
| GGA2 | -4225.0 |
| IGFBP5 | -4220.0 |
| PLAUR | -4209.0 |
| EPRS1 | -4204.0 |
| MRPL44 | -4200.0 |
| THBS2 | -4197.0 |
| FKBP9 | -4190.0 |
| COG4 | -4189.0 |
| PSMC2 | -4179.0 |
| EEF1B2 | -4177.0 |
| GSN | -4173.0 |
| POMT1 | -4165.0 |
| TTLL11 | -4160.0 |
| RPL13 | -4148.0 |
| SAR1B | -4109.0 |
| CCT7 | -4106.0 |
| MRPS18C | -4105.0 |
| RELA | -4097.0 |
| PIGH | -4069.0 |
| IKBKE | -4068.0 |
| KLHL22 | -4065.0 |
| PFDN5 | -4064.0 |
| TBC1D20 | -4050.0 |
| RPL8 | -4049.0 |
| FBXO27 | -4047.0 |
| RPS18 | -4032.0 |
| FBXO7 | -4031.0 |
| RPS10 | -4028.0 |
| ITM2B | -4024.0 |
| RPS29 | -4009.0 |
| PCNA | -3997.0 |
| SEC11A | -3992.0 |
| DPM3 | -3983.0 |
| GALNT12 | -3979.0 |
| SEC22C | -3930.0 |
| AMTN | -3913.0 |
| MRPS26 | -3891.0 |
| FBXO9 | -3877.0 |
| RPS21 | -3873.0 |
| EIF3K | -3868.0 |
| SPCS2 | -3859.0 |
| PSMD10 | -3849.0 |
| POFUT2 | -3827.0 |
| TUBA4A | -3824.0 |
| KARS1 | -3801.0 |
| VDR | -3798.0 |
| FAM20A | -3783.0 |
| MRPL58 | -3776.0 |
| MSRB1 | -3756.0 |
| TRAPPC9 | -3743.0 |
| RPS5 | -3741.0 |
| CNTN4 | -3734.0 |
| MRPS15 | -3732.0 |
| MBD6 | -3726.0 |
| BTRC | -3694.0 |
| SSR2 | -3693.0 |
| HLA-A | -3688.0 |
| NFRKB | -3680.0 |
| MRPL52 | -3676.0 |
| MAGT1 | -3673.0 |
| WFS1 | -3671.0 |
| COMMD7 | -3640.0 |
| UGGT1 | -3622.0 |
| EXOC4 | -3619.0 |
| CDC20 | -3613.0 |
| N6AMT1 | -3612.0 |
| DPH7 | -3605.0 |
| NUP214 | -3603.0 |
| MGAT2 | -3597.0 |
| DHPS | -3587.0 |
| RTN4RL2 | -3585.0 |
| RNF7 | -3583.0 |
| YY1 | -3581.0 |
| MRPS14 | -3575.0 |
| RPS11 | -3569.0 |
| B3GNTL1 | -3568.0 |
| RPL15 | -3543.0 |
| LMAN1 | -3539.0 |
| RPLP1 | -3524.0 |
| RPL36 | -3523.0 |
| TGFA | -3504.0 |
| EIF3I | -3488.0 |
| USO1 | -3487.0 |
| YARS1 | -3481.0 |
| RPL4 | -3472.0 |
| MRPL11 | -3457.0 |
| USP30 | -3448.0 |
| COMMD4 | -3443.0 |
| ASB5 | -3435.0 |
| SARS2 | -3423.0 |
| COMMD6 | -3420.0 |
| MRPL33 | -3419.0 |
| CCT5 | -3418.0 |
| RUVBL1 | -3408.0 |
| H2BC5 | -3370.0 |
| TRAF3 | -3366.0 |
| ADAMTS2 | -3363.0 |
| RPL31 | -3359.0 |
| CUL9 | -3329.0 |
| PIGW | -3280.0 |
| MTIF2 | -3276.0 |
| RPL23 | -3274.0 |
| PIGU | -3244.0 |
| MRPL51 | -3240.0 |
| SPTB | -3234.0 |
| PSMA6 | -3225.0 |
| MAN2A2 | -3220.0 |
| COPS7B | -3219.0 |
| GARS1 | -3213.0 |
| RPL10 | -3210.0 |
| LAMB2 | -3202.0 |
| RPS25 | -3191.0 |
| RPL7A | -3188.0 |
| ATP6AP2 | -3183.0 |
| EDEM3 | -3174.0 |
| WSB2 | -3159.0 |
| SARS1 | -3156.0 |
| GALNT6 | -3153.0 |
| EEF1G | -3124.0 |
| AP3M1 | -3123.0 |
| CCNF | -3122.0 |
| PIGZ | -3115.0 |
| MGAT5 | -3110.0 |
| RPL12 | -3105.0 |
| SSR1 | -3101.0 |
| ARSI | -3079.0 |
| RPL29 | -3065.0 |
| TNC | -3058.0 |
| RAE1 | -3056.0 |
| USP22 | -3053.0 |
| UBE2V2 | -3043.0 |
| IGFBP6 | -3038.0 |
| RPS19 | -3032.0 |
| PSME1 | -3031.0 |
| RNF20 | -3029.0 |
| GNGT2 | -3028.0 |
| PGM3 | -3025.0 |
| NUP98 | -3024.0 |
| RPL30 | -3017.0 |
| TXN | -3012.0 |
| RTF1 | -3000.0 |
| C1GALT1C1 | -2997.0 |
| RPL19 | -2986.0 |
| ALG5 | -2985.0 |
| DOHH | -2983.0 |
| FBXO6 | -2980.0 |
| RPS8 | -2974.0 |
| RAB44 | -2971.0 |
| TRIM4 | -2969.0 |
| PGA3 | -2945.0 |
| FOXK2 | -2940.0 |
| FCSK | -2935.0 |
| CARS1 | -2934.0 |
| BRCA1 | -2933.0 |
| CDC25A | -2926.0 |
| MRPS5 | -2925.0 |
| COMMD1 | -2902.0 |
| BECN1 | -2887.0 |
| RPL35A | -2878.0 |
| RPLP0 | -2877.0 |
| MAN1A1 | -2863.0 |
| SRP14 | -2850.0 |
| TRAPPC4 | -2838.0 |
| DPH3 | -2835.0 |
| CREBBP | -2822.0 |
| RFT1 | -2817.0 |
| SRD5A3 | -2797.0 |
| ZNF350 | -2778.0 |
| COPS3 | -2773.0 |
| DERL2 | -2770.0 |
| TFPT | -2767.0 |
| MRPS33 | -2760.0 |
| GALNT17 | -2742.0 |
| HARS2 | -2740.0 |
| ARSB | -2736.0 |
| UBE2D2 | -2735.0 |
| PSMD7 | -2731.0 |
| RPL18 | -2728.0 |
| CCNE1 | -2722.0 |
| ICMT | -2721.0 |
| RPL18A | -2719.0 |
| FBXO4 | -2716.0 |
| RPL13A | -2708.0 |
| MBD1 | -2706.0 |
| ACTR5 | -2705.0 |
| EIF2B4 | -2700.0 |
| EEF2 | -2697.0 |
| RPL38 | -2691.0 |
| WDR5 | -2673.0 |
| NSF | -2666.0 |
| RPS27 | -2657.0 |
| PSMA5 | -2649.0 |
| HCFC1 | -2625.0 |
| MRPL45 | -2620.0 |
| APOL1 | -2619.0 |
| PSMC1 | -2604.0 |
| MRPL18 | -2588.0 |
| ZDHHC2 | -2577.0 |
| RPS17 | -2555.0 |
| ACHE | -2554.0 |
| SLC30A5 | -2548.0 |
| AR | -2536.0 |
| PIGK | -2511.0 |
| EIF5 | -2509.0 |
| ARCN1 | -2503.0 |
| RPS23 | -2494.0 |
| OTUB2 | -2489.0 |
| RPS15 | -2484.0 |
| HARS1 | -2472.0 |
| OXA1L | -2469.0 |
| RAB20 | -2452.0 |
| MRPS9 | -2449.0 |
| ALG8 | -2436.0 |
| RARS1 | -2420.0 |
| SPSB1 | -2411.0 |
| FBXW11 | -2408.0 |
| GALNT4 | -2395.0 |
| EIF3D | -2390.0 |
| RPL34 | -2389.0 |
| INO80B | -2375.0 |
| SLC30A6 | -2365.0 |
| NEGR1 | -2357.0 |
| EIF3G | -2353.0 |
| RPS3A | -2337.0 |
| USP10 | -2330.0 |
| RPL28 | -2326.0 |
| FBXO17 | -2307.0 |
| TUSC3 | -2306.0 |
| ADAMTS8 | -2265.0 |
| YARS2 | -2245.0 |
| RPLP2 | -2239.0 |
| BACE1 | -2231.0 |
| PGA5 | -2221.0 |
| NUP85 | -2218.0 |
| STAT3 | -2208.0 |
| HDAC4 | -2202.0 |
| RAB35 | -2190.0 |
| PIAS1 | -2173.0 |
| GALNT16 | -2172.0 |
| TNIP2 | -2170.0 |
| WDR20 | -2153.0 |
| OTOA | -2147.0 |
| PSMD14 | -2133.0 |
| RPL32 | -2131.0 |
| RPL3L | -2091.0 |
| CPE | -2083.0 |
| RPL23A | -2081.0 |
| ADAMTS6 | -2079.0 |
| RPS12 | -2076.0 |
| CARS2 | -2072.0 |
| CDCA8 | -2069.0 |
| RPS15A | -2051.0 |
| TRAM1 | -2020.0 |
| ST8SIA4 | -2014.0 |
| SAE1 | -2006.0 |
| KLHL11 | -2004.0 |
| B2M | -1976.0 |
| VCAN | -1970.0 |
| PEX14 | -1958.0 |
| TAF10 | -1955.0 |
| MRPL48 | -1949.0 |
| KBTBD6 | -1943.0 |
| COMMD8 | -1937.0 |
| FBXO40 | -1930.0 |
| RIPK1 | -1922.0 |
| NDC1 | -1920.0 |
| PIGG | -1917.0 |
| MXRA8 | -1894.0 |
| CASP8AP2 | -1860.0 |
| DCUN1D2 | -1817.0 |
| SUMO2 | -1786.0 |
| PSMD1 | -1782.0 |
| UBXN1 | -1779.0 |
| RPL10A | -1766.0 |
| COG6 | -1764.0 |
| MRPL35 | -1757.0 |
| PSMA4 | -1756.0 |
| RPS20 | -1746.0 |
| SPP1 | -1742.0 |
| RPL37A | -1736.0 |
| XRCC4 | -1735.0 |
| TTLL4 | -1734.0 |
| GOLM1 | -1727.0 |
| GNPNAT1 | -1722.0 |
| RPS28 | -1692.0 |
| CNIH1 | -1687.0 |
| ARRB1 | -1679.0 |
| TUBA8 | -1674.0 |
| RPS3 | -1643.0 |
| HNRNPC | -1642.0 |
| CALU | -1638.0 |
| NUB1 | -1628.0 |
| DNAJC24 | -1627.0 |
| PIAS3 | -1615.0 |
| DNMT1 | -1609.0 |
| EEF1A1 | -1605.0 |
| PSME2 | -1591.0 |
| ALG9 | -1588.0 |
| RPS7 | -1576.0 |
| ALG11 | -1573.0 |
| EIF3C | -1564.0 |
| KLHL9 | -1561.0 |
| EEF1D | -1531.0 |
| SATB2 | -1525.0 |
| RPL37 | -1517.0 |
| RAB9B | -1509.0 |
| MRPL21 | -1490.0 |
| PSMD11 | -1483.0 |
| FARS2 | -1472.0 |
| SPTAN1 | -1454.0 |
| VDAC3 | -1448.0 |
| PSMD5 | -1433.0 |
| MANEA | -1432.0 |
| COG2 | -1422.0 |
| OTUD7B | -1402.0 |
| TUBB3 | -1396.0 |
| RPS24 | -1390.0 |
| TUBB6 | -1389.0 |
| HNRNPK | -1387.0 |
| RAB10 | -1385.0 |
| CISH | -1383.0 |
| MUC1 | -1357.0 |
| SORL1 | -1339.0 |
| TBCA | -1329.0 |
| TOMM70 | -1316.0 |
| SAFB | -1313.0 |
| GMDS | -1304.0 |
| CTSH | -1301.0 |
| MRPL30 | -1292.0 |
| ZRANB1 | -1290.0 |
| PSMA2 | -1286.0 |
| RPL3 | -1283.0 |
| RBBP5 | -1273.0 |
| RAD18 | -1265.0 |
| MDGA1 | -1262.0 |
| GFPT1 | -1256.0 |
| DAP3 | -1255.0 |
| RPS6 | -1245.0 |
| AURKA | -1234.0 |
| ADAMTS14 | -1232.0 |
| SIN3A | -1221.0 |
| COPS2 | -1211.0 |
| FBXW4 | -1204.0 |
| CSNK2A1 | -1195.0 |
| CCDC8 | -1190.0 |
| CTSC | -1185.0 |
| B4GALT4 | -1184.0 |
| ARSD | -1170.0 |
| FBN1 | -1168.0 |
| SEC24D | -1154.0 |
| PIAS4 | -1127.0 |
| THRA | -1081.0 |
| MUC12 | -1066.0 |
| ADAMTS13 | -1058.0 |
| OBSL1 | -1051.0 |
| SCMH1 | -1046.0 |
| RPL26 | -1044.0 |
| COPS4 | -1031.0 |
| FBXL19 | -1026.0 |
| FBXO10 | -1005.0 |
| CHML | -983.0 |
| USP9X | -962.0 |
| CSNK1D | -956.0 |
| XPC | -942.0 |
| PTP4A2 | -940.0 |
| TTLL3 | -928.0 |
| NOP56 | -926.0 |
| RPL21 | -907.0 |
| USP2 | -897.0 |
| COPB1 | -893.0 |
| SPSB3 | -867.0 |
| FBXL5 | -865.0 |
| PROS1 | -863.0 |
| FARSB | -849.0 |
| RPL11 | -848.0 |
| MRPS36 | -836.0 |
| GOLGB1 | -831.0 |
| EIF5B | -830.0 |
| F8 | -828.0 |
| ZBED1 | -821.0 |
| RPL41 | -812.0 |
| ADAM10 | -804.0 |
| CDC34 | -803.0 |
| CAPZA2 | -802.0 |
| SRP72 | -795.0 |
| STS | -794.0 |
| TSPAN33 | -791.0 |
| TTF1 | -784.0 |
| PSMD13 | -754.0 |
| EEF1E1 | -752.0 |
| COG1 | -751.0 |
| ULBP2 | -743.0 |
| NUP205 | -738.0 |
| TTLL9 | -721.0 |
| EIF3L | -699.0 |
| AURKB | -685.0 |
| GORASP1 | -663.0 |
| B4GALT1 | -661.0 |
| NGLY1 | -653.0 |
| NUP42 | -641.0 |
| ADAMTS19 | -636.0 |
| F5 | -627.0 |
| RAB38 | -626.0 |
| RPL17 | -614.0 |
| DCAF6 | -606.0 |
| CDC73 | -598.0 |
| HDAC1 | -580.0 |
| RAB31 | -572.0 |
| PIGY | -555.5 |
| IGFBP3 | -549.0 |
| MTA1 | -545.0 |
| CANX | -540.0 |
| UBE2G2 | -536.0 |
| VWA1 | -525.0 |
| NUS1 | -501.0 |
| TFAP2C | -497.0 |
| GHRL | -496.0 |
| RPL6 | -483.0 |
| SNCA | -468.0 |
| UBE2R2 | -460.0 |
| RPS16 | -451.0 |
| MSRB2 | -430.0 |
| UBE2K | -426.0 |
| RPS2 | -411.0 |
| NTNG2 | -408.0 |
| PPP6C | -407.0 |
| RAB27B | -396.0 |
| ACTR10 | -373.0 |
| RPL14 | -367.0 |
| WARS2 | -359.0 |
| SNX3 | -340.0 |
| SOCS6 | -332.0 |
| MAN1A2 | -330.0 |
| FBXO21 | -329.0 |
| CTSG | -319.0 |
| PFDN4 | -314.0 |
| MRPS35 | -312.0 |
| TUBA1A | -304.0 |
| RPL24 | -289.0 |
| MAN2A1 | -288.0 |
| DARS2 | -273.0 |
| EP300 | -244.0 |
| PSMB8 | -235.0 |
| RAB2A | -220.0 |
| SVBP | -209.0 |
| STAM2 | -192.0 |
| TGFBI | -185.0 |
| COMMD2 | -183.0 |
| MRPL50 | -182.0 |
| MFGE8 | -175.0 |
| RPL5 | -160.0 |
| NUP153 | -156.0 |
| PFDN2 | -143.0 |
| SCFD1 | -136.0 |
| RCE1 | -125.0 |
| PRKDC | -116.0 |
| H2AZ1 | -91.0 |
| ALG10 | -89.0 |
| PIGC | -88.0 |
| TMED7 | -86.0 |
| STAMBP | -74.0 |
| PSME4 | -48.0 |
| CCT2 | -39.0 |
| RBBP7 | -26.0 |
| RPS9 | 11.0 |
| PSMD6 | 26.0 |
| CPM | 30.0 |
| EXOC8 | 34.0 |
| RECK | 37.0 |
| DCTN4 | 48.0 |
| TRAPPC6A | 58.0 |
| IGFBP2 | 82.0 |
| LYPD3 | 93.0 |
| SRP54 | 106.0 |
| CSNK2A2 | 111.0 |
| SEL1L | 121.0 |
| MRPS30 | 125.0 |
| TRAPPC10 | 129.0 |
| PAF1 | 135.0 |
| NFKBIA | 181.0 |
| USP21 | 193.0 |
| H2AC6 | 204.0 |
| SPTBN5 | 209.0 |
| RPS27L | 222.0 |
| RPS27A | 229.0 |
| RAB9A | 231.0 |
| SLC30A7 | 241.0 |
| RAD23B | 243.0 |
| NICN1 | 253.0 |
| CMA1 | 256.0 |
| KIF5A | 259.0 |
| KCTD7 | 290.0 |
| SENP8 | 291.0 |
| UBE2G1 | 327.0 |
| FEM1A | 336.0 |
| USP16 | 341.0 |
| RPL22 | 345.0 |
| KBTBD8 | 348.0 |
| H2AW | 354.0 |
| FBXL13 | 359.0 |
| PSMA1 | 379.0 |
| ARFGAP3 | 381.0 |
| RPL39 | 390.0 |
| MYO5A | 391.0 |
| IARS2 | 392.0 |
| FEM1B | 396.0 |
| H2BU1 | 397.0 |
| TGFBR1 | 415.0 |
| OTULIN | 451.0 |
| CD109 | 455.0 |
| UBE2A | 466.0 |
| RAB40A | 478.0 |
| RPS4Y1 | 514.0 |
| GOSR1 | 516.0 |
| TECTA | 537.0 |
| KTN1 | 539.0 |
| GNG10 | 545.0 |
| SAA1 | 558.0 |
| FOXK1 | 598.0 |
| MGAT4A | 612.0 |
| CCT6A | 617.0 |
| ART3 | 618.0 |
| GNE | 621.0 |
| VHL | 652.0 |
| USP37 | 673.0 |
| OGT | 674.0 |
| ESR1 | 690.0 |
| NAPG | 703.0 |
| COG7 | 714.0 |
| SMC1A | 733.0 |
| B3GNT8 | 739.0 |
| PIGN | 742.0 |
| EIF2S1 | 771.0 |
| ST3GAL4 | 774.0 |
| MRPL19 | 782.0 |
| RAB4B | 790.0 |
| KLHL25 | 799.0 |
| RAB4A | 839.0 |
| RAB18 | 879.0 |
| HSPG2 | 885.0 |
| DCAF8 | 886.0 |
| PML | 912.0 |
| ALG14 | 928.0 |
| SEC23A | 932.0 |
| RNF139 | 972.0 |
| LEO1 | 991.0 |
| RPS13 | 1006.0 |
| GSPT1 | 1018.0 |
| OTUD7A | 1027.0 |
| COPS5 | 1035.0 |
| TTLL5 | 1043.0 |
| COMMD3 | 1045.0 |
| MTFMT | 1111.0 |
| ST3GAL3 | 1150.0 |
| BST1 | 1165.0 |
| DDB2 | 1173.0 |
| XPNPEP2 | 1197.0 |
| ASXL2 | 1205.0 |
| TPGS2 | 1217.0 |
| MRPL1 | 1222.0 |
| SENP5 | 1269.0 |
| FBXL3 | 1274.0 |
| XRN2 | 1280.0 |
| ADRB2 | 1284.0 |
| FBXL14 | 1285.0 |
| LARS2 | 1293.0 |
| MAP3K7 | 1306.0 |
| ASB7 | 1320.0 |
| PIGP | 1336.0 |
| IARS1 | 1339.0 |
| RAB29 | 1342.0 |
| ALPL | 1363.0 |
| DNAJC3 | 1382.0 |
| SFTPD | 1388.0 |
| CUL1 | 1406.0 |
| EIF4A1 | 1415.0 |
| TOMM20 | 1480.0 |
| EIF1AX | 1508.0 |
| YOD1 | 1509.0 |
| GFM2 | 1532.0 |
| UBE2E1 | 1544.0 |
| RAB13 | 1575.0 |
| UBE2T | 1590.0 |
| MIA3 | 1620.0 |
| CMAS | 1623.0 |
| CALM1 | 1638.0 |
| RAB1A | 1661.0 |
| ACTL6A | 1675.0 |
| USP24 | 1681.0 |
| GALNT13 | 1700.0 |
| CCNA2 | 1702.0 |
| MRPL32 | 1711.0 |
| GALNT18 | 1728.0 |
| CAPZA1 | 1732.0 |
| UBE2N | 1734.0 |
| RPL7 | 1738.0 |
| ETF1 | 1743.0 |
| UBE2C | 1747.0 |
| CCT4 | 1759.0 |
| FBXO22 | 1768.0 |
| STAG2 | 1773.0 |
| H2BC21 | 1774.0 |
| B4GALT5 | 1807.0 |
| FBXL12 | 1810.0 |
| APC | 1828.0 |
| DCAF10 | 1842.0 |
| RAB2B | 1849.0 |
| NARS1 | 1852.0 |
| CHM | 1855.0 |
| EVA1A | 1857.0 |
| GALNT8 | 1860.0 |
| USP8 | 1874.0 |
| RAB14 | 1901.0 |
| DPM1 | 1909.0 |
| MME | 1917.0 |
| RAB24 | 1920.0 |
| FBXW2 | 1926.0 |
| RAB22A | 1939.0 |
| THRB | 1943.0 |
| EIF3J | 1946.0 |
| TGFBR2 | 1948.0 |
| KIF13A | 1949.0 |
| AARS2 | 1953.0 |
| BMI1 | 1962.0 |
| RAB33B | 1966.0 |
| DCUN1D5 | 1976.0 |
| TP53BP1 | 1989.0 |
| COG5 | 1992.0 |
| DTL | 1996.0 |
| EID3 | 2028.0 |
| CUL4A | 2033.0 |
| NR3C1 | 2034.0 |
| RAB6A | 2072.0 |
| EIF4B | 2088.0 |
| RARS2 | 2099.0 |
| HIF3A | 2112.0 |
| NUP155 | 2114.0 |
| TARS1 | 2126.0 |
| NUP35 | 2129.0 |
| MGAT4C | 2130.0 |
| UBE2B | 2133.0 |
| H2AC18 | 2134.0 |
| FPGT | 2142.0 |
| SRP19 | 2150.0 |
| NUP54 | 2157.0 |
| SENP1 | 2163.0 |
| IGFBP4 | 2172.0 |
| FBXW8 | 2188.0 |
| VCPIP1 | 2192.0 |
| USP18 | 2206.0 |
| BTBD1 | 2212.0 |
| USP14 | 2217.0 |
| AIMP1 | 2228.0 |
| SMAD4 | 2253.0 |
| USP7 | 2256.0 |
| CSF2RB | 2267.0 |
| TSPAN14 | 2269.0 |
| KIFC3 | 2270.0 |
| DPH5 | 2293.0 |
| PPA2 | 2296.0 |
| SMURF2 | 2303.0 |
| RAB43 | 2319.0 |
| ASXL1 | 2331.0 |
| SRP9 | 2333.0 |
| ASB15 | 2375.0 |
| EIF4E | 2379.0 |
| RAD21 | 2392.0 |
| COPS8 | 2419.0 |
| NUP43 | 2453.0 |
| MT-RNR1 | 2469.0 |
| RAB39A | 2479.0 |
| CTR9 | 2482.0 |
| TOP2A | 2491.0 |
| FN3K | 2508.0 |
| VBP1 | 2521.0 |
| SIAH2 | 2522.0 |
| TAF9B | 2561.0 |
| MRPS25 | 2586.0 |
| PPA1 | 2589.0 |
| MAT2B | 2590.0 |
| TRIM13 | 2646.0 |
| DYNC1LI2 | 2656.0 |
| USP12 | 2665.0 |
| ASB16 | 2681.0 |
| RPL36A | 2688.0 |
| PGA4 | 2694.0 |
| NANP | 2777.0 |
| INO80C | 2780.0 |
| B3GLCT | 2794.0 |
| PIGB | 2795.0 |
| PIGL | 2806.0 |
| CYLD | 2838.0 |
| HERC2 | 2845.0 |
| FBXL4 | 2850.0 |
| IFIH1 | 2853.0 |
| WDR48 | 2906.0 |
| COMMD10 | 2920.0 |
| MRPS28 | 2930.0 |
| TTL | 2935.0 |
| SEC23IP | 2953.0 |
| PDCL | 2956.0 |
| GNG12 | 2973.0 |
| C3 | 2977.0 |
| BLM | 2987.0 |
| CCT8 | 3002.0 |
| GALNT1 | 3072.0 |
| KCTD6 | 3088.0 |
| TRAPPC2 | 3092.0 |
| EIF2S2 | 3109.0 |
| SPON1 | 3126.0 |
| NTM | 3148.0 |
| WAC | 3155.0 |
| FBXO30 | 3156.0 |
| RANBP2 | 3171.0 |
| SNCAIP | 3174.0 |
| RPSA | 3175.0 |
| SLC35A1 | 3178.0 |
| DYNC1I2 | 3198.0 |
| USP34 | 3206.0 |
| KLHL20 | 3230.0 |
| EIF3E | 3234.0 |
| STAG1 | 3239.0 |
| DPH1 | 3243.0 |
| UBC | 3246.0 |
| ELOC | 3260.0 |
| EIF3H | 3301.0 |
| CUL5 | 3316.0 |
| CAMKMT | 3320.0 |
| KAT2A | 3322.0 |
| RAB23 | 3327.0 |
| UCHL5 | 3343.0 |
| KLHL13 | 3381.0 |
| GALNT7 | 3383.0 |
| PCGF2 | 3410.0 |
| UBA3 | 3420.0 |
| PUM2 | 3425.0 |
| SPON2 | 3448.0 |
| GNG2 | 3460.0 |
| NCOA2 | 3470.0 |
| GFM1 | 3529.0 |
| CPB1 | 3535.0 |
| LONP2 | 3561.0 |
| MMP2 | 3573.0 |
| SEC24A | 3580.0 |
| EDEM1 | 3611.0 |
| AXIN2 | 3643.0 |
| PSMD12 | 3658.0 |
| NUP133 | 3662.0 |
| EIF2S3 | 3667.0 |
| BIRC2 | 3674.0 |
| CUL2 | 3685.0 |
| SEC16B | 3690.0 |
| TNKS | 3694.0 |
| DPP4 | 3716.0 |
| FOXO4 | 3729.0 |
| PTCD3 | 3730.0 |
| USP3 | 3738.0 |
| UBE2D3 | 3753.0 |
| MAN1C1 | 3794.0 |
| PSMC6 | 3801.0 |
| NUDT14 | 3804.0 |
| KIF5B | 3823.0 |
| EXOC1 | 3838.0 |
| NLRP3 | 3857.0 |
| VASH1 | 3873.0 |
| ALG10B | 3876.0 |
| RWDD3 | 3879.0 |
| RAB6B | 3883.0 |
| COG3 | 3893.0 |
| NSMCE2 | 3902.0 |
| SPCS3 | 3905.0 |
| NCOA1 | 3941.0 |
| SEC24B | 3945.0 |
| SUZ12 | 3951.0 |
| SATB1 | 3955.0 |
| RNF2 | 3972.0 |
| SUMO1 | 3974.0 |
| DNMT3A | 3975.0 |
| H3-3A | 4015.0 |
| TOP2B | 4017.0 |
| ASB2 | 4032.0 |
| KAT2B | 4056.0 |
| METTL22 | 4058.0 |
| CAND1 | 4089.0 |
| SENP2 | 4091.0 |
| DCAF5 | 4093.0 |
| RHOT1 | 4095.0 |
| UBE2Q2 | 4114.0 |
| PSMB9 | 4121.0 |
| ING2 | 4130.0 |
| GCNT1 | 4151.0 |
| RAB12 | 4152.0 |
| TCP1 | 4158.0 |
| EXOC2 | 4164.0 |
| BRCC3 | 4165.0 |
| FBXO32 | 4176.0 |
| KLHL2 | 4179.0 |
| NAE1 | 4185.0 |
| DCAF13 | 4213.0 |
| SP3 | 4244.0 |
| GRIA1 | 4245.0 |
| RAB8B | 4281.0 |
| PIGX | 4282.0 |
| USP15 | 4285.0 |
| TNKS2 | 4320.0 |
| EIF3M | 4326.0 |
| CHD3 | 4330.0 |
| ST3GAL5 | 4332.0 |
| SEH1L | 4352.0 |
| PHC1 | 4367.0 |
| UBA6 | 4398.0 |
| LSAMP | 4400.0 |
| FBXL20 | 4403.0 |
| MRPL39 | 4422.0 |
| USP28 | 4436.0 |
| DDX17 | 4440.0 |
| P2RY2 | 4446.0 |
| KIN | 4451.0 |
| SERPINA10 | 4458.0 |
| MRPS31 | 4480.0 |
| NUP58 | 4488.0 |
| NFKB2 | 4495.0 |
| PPARG | 4509.0 |
| ST6GAL1 | 4514.0 |
| MITF | 4532.0 |
| GNB4 | 4535.0 |
| B3GNT4 | 4549.0 |
| CCNE2 | 4551.0 |
| ASB14 | 4566.0 |
| LAMC1 | 4580.0 |
| PEX13 | 4592.0 |
| CUL3 | 4595.0 |
| UBXN7 | 4609.0 |
| FBXL7 | 4619.0 |
| PABPC1 | 4660.0 |
| FBXW12 | 4698.0 |
| ERO1A | 4711.0 |
| RPL36AL | 4730.0 |
| DARS1 | 4742.0 |
| IGF2 | 4747.0 |
| CBX4 | 4782.0 |
| SMC3 | 4789.0 |
| PRSS23 | 4797.0 |
| SHPRH | 4829.0 |
| TBCD | 4831.0 |
| HLA-B | 4836.0 |
| ST3GAL2 | 4843.0 |
| TRAPPC6B | 4845.0 |
| SPRN | 4851.0 |
| RPL9 | 4853.0 |
| GNA14 | 4861.0 |
| B3GNT7 | 4875.0 |
| MCFD2 | 4888.0 |
| B4GALT3 | 4889.0 |
| TOP1 | 4912.0 |
| EXOC5 | 4932.0 |
| UIMC1 | 4937.0 |
| APH1B | 4938.0 |
| ERCC8 | 4950.0 |
| ASB9 | 4957.0 |
| EIF5A2 | 5005.0 |
| B3GNT2 | 5007.0 |
| PGR | 5027.0 |
| RABGGTB | 5039.0 |
| SPTBN1 | 5040.0 |
| HRC | 5041.0 |
| ETFBKMT | 5047.0 |
| ADRA2C | 5056.0 |
| PSMA3 | 5077.0 |
| RPL22L1 | 5078.0 |
| DCUN1D1 | 5093.0 |
| CHRDL1 | 5113.0 |
| RNF103 | 5131.0 |
| ARFGEF2 | 5142.0 |
| STAM | 5156.0 |
| USP47 | 5189.0 |
| TSPAN5 | 5224.0 |
| NUP160 | 5248.0 |
| ALG13 | 5249.0 |
| SUDS3 | 5287.0 |
| HDAC7 | 5297.0 |
| EIF3A | 5298.0 |
| SEC61A2 | 5305.0 |
| RAB27A | 5323.0 |
| UBE2H | 5344.0 |
| AGBL3 | 5356.0 |
| SMC6 | 5366.0 |
| MRRF | 5368.0 |
| USP42 | 5369.0 |
| MDM2 | 5371.0 |
| SEM1 | 5372.0 |
| HLTF | 5377.0 |
| UBE2S | 5380.0 |
| ASGR2 | 5395.0 |
| UBE2D1 | 5427.0 |
| FBXO11 | 5446.0 |
| ATXN3 | 5486.0 |
| RAB5A | 5503.0 |
| MBD5 | 5525.0 |
| PPP6R3 | 5531.0 |
| RAB3A | 5550.0 |
| GAS6 | 5559.0 |
| ST6GAL2 | 5571.0 |
| UBA2 | 5577.0 |
| RAB15 | 5595.0 |
| NPM1 | 5611.0 |
| AOPEP | 5615.0 |
| ST8SIA5 | 5624.0 |
| NARS2 | 5656.0 |
| EXOC6 | 5696.0 |
| SPTBN2 | 5752.0 |
| CTNNB1 | 5757.0 |
| NUP50 | 5758.0 |
| MTIF3 | 5760.0 |
| BGLAP | 5805.0 |
| INO80D | 5850.0 |
| PGAP1 | 5851.0 |
| CBX2 | 5858.0 |
| GALNT3 | 5872.0 |
| BARD1 | 5883.0 |
| SMAD2 | 5913.0 |
| TULP4 | 5934.0 |
| PRMT3 | 5939.0 |
| SMC5 | 5946.0 |
| DCAF17 | 5949.0 |
| LARS1 | 6001.0 |
| CD59 | 6004.0 |
| UGGT2 | 6005.0 |
| BIRC3 | 6018.0 |
| INHBA | 6048.0 |
| B3GNT3 | 6092.0 |
| PIAS2 | 6094.0 |
| WRN | 6108.0 |
| NOP58 | 6115.0 |
| PHC3 | 6121.0 |
| MGAT3 | 6122.0 |
| GCNT3 | 6123.0 |
| PLA2G7 | 6140.0 |
| HDAC2 | 6141.0 |
| RAB21 | 6148.0 |
| DCAF16 | 6173.0 |
| RNF146 | 6176.0 |
| ARSK | 6184.0 |
| LYPD5 | 6212.0 |
| USP33 | 6231.0 |
| CCDC59 | 6243.0 |
| EIF2B3 | 6253.0 |
| LARGE1 | 6267.0 |
| DYNC1LI1 | 6270.0 |
| ASGR1 | 6280.0 |
| MARCHF6 | 6307.0 |
| USP48 | 6318.0 |
| SOCS5 | 6321.0 |
| NSMCE4A | 6327.0 |
| TMEM132A | 6336.0 |
| CCT6B | 6337.0 |
| RAD52 | 6357.0 |
| ARSJ | 6373.0 |
| B4GALNT2 | 6425.0 |
| TOPORS | 6434.0 |
| FBXW7 | 6440.0 |
| CCP110 | 6457.0 |
| METTL21A | 6498.0 |
| FSTL3 | 6522.0 |
| RARA | 6535.0 |
| PPARGC1A | 6593.0 |
| NOD1 | 6632.0 |
| FBXO31 | 6642.0 |
| LAMB1 | 6643.0 |
| IDE | 6644.0 |
| USP25 | 6658.0 |
| MRPL42 | 6674.0 |
| MIA2 | 6675.0 |
| KLHL5 | 6693.0 |
| GAN | 6694.0 |
| GNAQ | 6700.0 |
| GNB5 | 6724.0 |
| RAB11A | 6758.0 |
| CDK1 | 6780.0 |
| RORA | 6791.0 |
| THSD7A | 6817.0 |
| OTUD3 | 6875.0 |
| CNIH3 | 6900.0 |
| EIF4A2 | 6916.0 |
| BET1 | 6923.0 |
| ATXN7 | 6942.0 |
| TRIM25 | 6947.0 |
| TDG | 6968.0 |
| VNN1 | 6989.0 |
| LYPD1 | 7000.0 |
| PTEN | 7006.0 |
| NR3C2 | 7022.0 |
| NAPB | 7024.0 |
| RAB3C | 7033.0 |
| ANKRD28 | 7067.0 |
| GNG4 | 7087.0 |
| CUL4B | 7088.0 |
| LRRC49 | 7126.0 |
| LMO7 | 7131.0 |
| TNIP3 | 7133.0 |
| GATA3 | 7139.0 |
| POLB | 7155.0 |
| PAX6 | 7185.0 |
| ASB3 | 7208.0 |
| SPARCL1 | 7231.0 |
| TRAF6 | 7237.0 |
| ADORA2A | 7261.0 |
| RGS11 | 7270.0 |
| HIF1A | 7278.0 |
| UBE2W | 7287.0 |
| TUBB1 | 7292.0 |
| JOSD1 | 7301.0 |
| RCN1 | 7303.0 |
| SP100 | 7340.0 |
| ANK2 | 7369.0 |
| GPIHBP1 | 7380.0 |
| DCUN1D3 | 7393.0 |
| TTLL7 | 7420.0 |
| KLHL42 | 7422.0 |
| RAB30 | 7434.0 |
| KLHL21 | 7460.0 |
| FUT8 | 7476.0 |
| RGS9 | 7520.0 |
| MYSM1 | 7546.0 |
| PCSK2 | 7565.0 |
| ZNF131 | 7600.0 |
| RNF168 | 7636.0 |
| DPH6 | 7659.0 |
| DYNC1I1 | 7687.0 |
| RAB3B | 7729.0 |
| DDX58 | 7734.0 |
| TBCE | 7763.0 |
| TUBB2B | 7803.0 |
| PAPPA2 | 7814.0 |
| B4GALT6 | 7825.0 |
| B3GALNT2 | 7827.0 |
| THSD1 | 7840.0 |
| MTRF1L | 7847.0 |
| TUBB2A | 7849.0 |
| ASB4 | 7855.0 |
| ST6GALNAC1 | 7860.0 |
| ERO1B | 7869.0 |
| SKP2 | 7870.0 |
| DNMT3B | 7873.0 |
| TCF7L2 | 7879.0 |
| STX17 | 7909.0 |
| MYC | 7937.0 |
| AREG | 7970.0 |
| USP49 | 7998.0 |
| ADAMTS12 | 8006.0 |
| TNFAIP3 | 8015.0 |
| CBX8 | 8025.0 |
| DDX5 | 8105.0 |
| RAB17 | 8106.0 |
| ANKRD9 | 8112.0 |
| MDM4 | 8113.0 |
| TF | 8137.0 |
| AGBL2 | 8150.0 |
| ST8SIA1 | 8155.0 |
| PAPPA | 8197.0 |
| KLK2 | 8225.0 |
| EPAS1 | 8247.0 |
| THY1 | 8270.0 |
| BCL10 | 8277.0 |
| STAMBPL1 | 8314.0 |
| AGT | 8316.0 |
| VASH2 | 8373.0 |
| FBXL22 | 8385.0 |
| VCPKMT | 8388.0 |
| SSPOP | 8392.0 |
| GPC3 | 8446.0 |
| MT-RNR2 | 8527.0 |
| POMK | 8570.0 |
| AGTPBP1 | 8608.0 |
| GPLD1 | 8648.0 |
| GATA6 | 8650.0 |
| PLG | 8713.0 |
| ST3GAL6 | 8762.0 |
| MYRIP | 8765.0 |
| DCUN1D4 | 8786.0 |
| MATN3 | 8811.0 |
| NR2C1 | 8813.0 |
| FGF23 | 8821.0 |
| ALG6 | 8828.0 |
| F10 | 8831.0 |
| USP13 | 8835.0 |
| BIRC5 | 8840.0 |
| ST6GALNAC2 | 8874.0 |
| NRN1 | 8915.0 |
| GNG11 | 8919.0 |
| FEM1C | 8932.0 |
| RIPK2 | 8936.0 |
| SMAD7 | 8944.0 |
| NTNG1 | 8947.0 |
| B3GNT5 | 8990.0 |
| ADRA2A | 9012.0 |
| RNF144A | 9021.0 |
| ST6GALNAC3 | 9031.0 |
| MSRB3 | 9202.0 |
| NUP107 | 9235.0 |
| SPTA1 | 9241.0 |
| SOCS2 | 9251.0 |
| FBXO15 | 9320.0 |
| SIAH1 | 9417.0 |
| CLSPN | 9486.0 |
| HIC1 | 9512.0 |
| SPHK1 | 9530.0 |
| LMCD1 | 9606.0 |
| WSB1 | 9620.0 |
| MUC3A | 9677.0 |
| ADAMTS1 | 9694.0 |
| IGFBP7 | 9699.0 |
| PIGA | 9708.0 |
| KLF4 | 9710.0 |
| NR5A2 | 9715.0 |
| IL33 | 9720.0 |
| KIF5C | 9732.0 |
| ST8SIA6 | 9759.0 |
| CRHR2 | 9825.0 |
| KLHL3 | 9836.0 |
| IL6 | 9872.0 |
| UHRF2 | 9931.0 |
| VNN2 | 9938.0 |
| ADAMTSL1 | 9951.0 |
| ART4 | 9955.0 |
| ADAMTS4 | 9961.0 |
| STC2 | 9978.0 |
| NR4A2 | 9993.0 |
| GCNT4 | 10004.0 |
| SOCS3 | 10041.0 |
| SEMA5B | 10059.0 |
| ADAMTS18 | 10060.0 |
| THBS1 | 10064.0 |
| INHBB | 10079.0 |
| RNF152 | 10082.0 |
| ENPEP | 10090.0 |
| SMAD1 | 10096.0 |
| ACE | 10107.0 |
| TUBAL3 | 10108.0 |
| ADAMTS9 | 10114.0 |
| FCGR3B | 10145.0 |
| ADGRF5 | 10164.0 |
Immune System
| 543 | |
|---|---|
| set | Immune System |
| setSize | 1744 |
| pANOVA | 3.01e-30 |
| s.dist | -0.165 |
| p.adjustANOVA | 1.09e-27 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| MUC20 | -9146 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| DEFB1 | -9133 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGHM | -9118 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| MUC20 | -9146 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| DEFB1 | -9133 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGHM | -9118 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| SIRPB1 | -9101 |
| SIGLEC7 | -9100 |
| IGHV2-5 | -9098 |
| NCF1 | -9092 |
| IGKC | -9087 |
| IGHD | -9085 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| MAPK7 | -9047 |
| CXCL10 | -9043 |
| CD79A | -9036 |
| CYB5R3 | -9018 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| SLAMF7 | -8988 |
| SERPINA1 | -8963 |
| IGHV1-2 | -8953 |
| GRN | -8951 |
| CSF2RA | -8945 |
| LILRA2 | -8939 |
| GAA | -8936 |
| LAMP1 | -8930 |
| MLST8 | -8926 |
| OSCAR | -8923 |
| CKAP4 | -8916 |
| TMBIM1 | -8914 |
| IGHV1-46 | -8910 |
| TNFSF13 | -8882 |
| IGKV2D-28 | -8875 |
| IGHG4 | -8874 |
| CTSA | -8873 |
| FCER2 | -8869 |
| CSK | -8867 |
| S100A11 | -8865 |
| IGKV3-11 | -8864 |
| CD81 | -8856 |
| CD68 | -8853 |
| ALDH3B1 | -8840 |
| NDN | -8839 |
| IGKV1D-39 | -8828 |
| PTPN18 | -8820 |
| NCSTN | -8815 |
| IL2RA | -8814 |
| FGR | -8811 |
| ORMDL3 | -8807 |
| IGLV3-21 | -8806 |
| CSTB | -8805 |
| P4HB | -8801 |
| SURF4 | -8799 |
| RNASE2 | -8797 |
| C1QC | -8796 |
| UNC93B1 | -8794 |
| CD99 | -8784 |
| TIMP1 | -8781 |
| CLEC4G | -8780 |
| HLA-DQA1 | -8774 |
| IGLV3-25 | -8773 |
| FN1 | -8771 |
| PIK3R2 | -8767 |
| CYBA | -8747 |
| CD4 | -8741 |
| RNASE6 | -8739 |
| NUP210 | -8727 |
| TRIM68 | -8719 |
| TREML1 | -8715 |
| RNF135 | -8690 |
| S100B | -8689 |
| ASB13 | -8677 |
| APOB | -8671 |
| JAK3 | -8657 |
| ITLN1 | -8655 |
| SEC13 | -8653 |
| HK3 | -8652 |
| ALDOA | -8627 |
| ATP6V0E2 | -8624 |
| ITGB2 | -8620 |
| CFB | -8616 |
| IGHV3-33 | -8608 |
| ADGRE5 | -8603 |
| TUBB | -8597 |
| SIGLEC14 | -8594 |
| MS4A2 | -8592 |
| FBXW5 | -8591 |
| RNF220 | -8590 |
| WAS | -8588 |
| IGLV2-14 | -8572 |
| ITGB7 | -8556 |
| ANPEP | -8527 |
| C1QB | -8526 |
| MAN2B1 | -8524 |
| CRLF1 | -8500 |
| DOK3 | -8498 |
| CTSB | -8493 |
| PRKACA | -8490 |
| LAIR1 | -8472 |
| COMMD9 | -8460 |
| BPIFB4 | -8459 |
| SLC11A1 | -8457 |
| CD180 | -8455 |
| AKT1 | -8448 |
| TREM1 | -8429 |
| IRAK1 | -8427 |
| PILRA | -8421 |
| ATP6V0C | -8415 |
| SIGLEC1 | -8398 |
| MADCAM1 | -8397 |
| CLU | -8383 |
| ATG7 | -8380 |
| LILRB2 | -8379 |
| ATP6V1F | -8374 |
| PTPN6 | -8357 |
| TYROBP | -8356 |
| PSMD3 | -8328 |
| GPR84 | -8320 |
| PLD3 | -8311 |
| PPL | -8305 |
| RHOG | -8288 |
| TNFRSF11B | -8282 |
| TGFB1 | -8281 |
| SIGLEC16 | -8279 |
| TOLLIP | -8276 |
| IFI30 | -8275 |
| GHDC | -8267 |
| FUCA2 | -8249 |
| HCK | -8242 |
| BCL2L1 | -8236 |
| PIN1 | -8233 |
| CD8B | -8225 |
| DPP7 | -8205 |
| GLB1 | -8189 |
| MAPKAPK3 | -8188 |
| LYZ | -8186 |
| AP1B1 | -8173 |
| FOLR3 | -8171 |
| LGALS9 | -8167 |
| MRC2 | -8158 |
| PDCD1 | -8157 |
| DCTN1 | -8155 |
| PSMD8 | -8149 |
| SRC | -8148 |
| STUB1 | -8141 |
| SLAMF6 | -8138 |
| MMP3 | -8131 |
| APRT | -8130 |
| FCER1G | -8128 |
| IL12RB1 | -8125 |
| C2 | -8124 |
| IGLV1-40 | -8088 |
| POLR3H | -8087 |
| ALDOC | -8085 |
| C1QA | -8083 |
| CD55 | -8080 |
| CSNK2B | -8078 |
| SIGLEC5 | -8058 |
| SEC61A1 | -8056 |
| FCGR3A | -8055 |
| LILRB3 | -8035 |
| CXCL1 | -8034 |
| NLRX1 | -8024 |
| IFNGR2 | -8015 |
| EIF4G1 | -8010 |
| MYD88 | -8007 |
| GALNS | -7969 |
| CD209 | -7967 |
| TRAPPC1 | -7966 |
| CD27 | -7963 |
| LILRB4 | -7957 |
| PSAP | -7953 |
| AP2M1 | -7945 |
| KCNAB2 | -7943 |
| CAPN1 | -7920 |
| TXNDC5 | -7914 |
| DDOST | -7902 |
| POM121C | -7894 |
| CTSD | -7893 |
| POMC | -7890 |
| POLR2E | -7886 |
| TAPBP | -7871 |
| LIMK1 | -7870 |
| CANT1 | -7866 |
| BAIAP2 | -7839 |
| AP2S1 | -7829 |
| FTL | -7828 |
| SIPA1 | -7823 |
| VAV1 | -7822 |
| ITGB5 | -7819 |
| KEAP1 | -7807 |
| ITGAM | -7806 |
| DBNL | -7804 |
| RASGRP4 | -7795 |
| STX1A | -7794 |
| IMPDH1 | -7786 |
| ALOX5 | -7785 |
| TPR | -7773 |
| TRIM32 | -7764 |
| PDIA3 | -7754 |
| BTBD6 | -7737 |
| CSF1R | -7734 |
| ARF1 | -7717 |
| CARD9 | -7716 |
| PSMB10 | -7709 |
| DCTN3 | -7698 |
| MAP2K7 | -7697 |
| IL17RC | -7694 |
| RNASET2 | -7680 |
| GSTP1 | -7676 |
| TMEM179B | -7675 |
| CNTFR | -7651 |
| MVP | -7640 |
| APEH | -7616 |
| CD300A | -7613 |
| ASB1 | -7607 |
| THOP1 | -7606 |
| ARPC1B | -7593 |
| F13A1 | -7586 |
| CTSZ | -7584 |
| METTL7A | -7577 |
| PSMB5 | -7576 |
| MUC4 | -7552 |
| UBE2M | -7541 |
| DNM1 | -7539 |
| CNPY3 | -7536 |
| VAMP8 | -7535 |
| KLC4 | -7532 |
| CUL7 | -7521 |
| GM2A | -7520 |
| ASB11 | -7514 |
| DNASE1L1 | -7509 |
| CD53 | -7506 |
| UBA1 | -7503 |
| FADD | -7501 |
| PKM | -7496 |
| CD63 | -7486 |
| VAT1 | -7456 |
| TRIM14 | -7440 |
| ARSA | -7432 |
| GUSB | -7411 |
| UBE2J2 | -7410 |
| LILRB5 | -7407 |
| IGKV3-15 | -7403 |
| DCTN5 | -7397 |
| RILP | -7393 |
| AKT2 | -7377 |
| IKBKG | -7367 |
| RAB3D | -7358 |
| HLA-DQB1 | -7344 |
| LAMTOR1 | -7337 |
| LRRC41 | -7324 |
| DCTN2 | -7295 |
| TREM2 | -7286 |
| PSME3 | -7280 |
| IRF5 | -7277 |
| EIF4E2 | -7273 |
| UBE2D4 | -7271 |
| PSMB2 | -7268 |
| PRG2 | -7266 |
| AAMP | -7244 |
| NKIRAS2 | -7217 |
| GRB2 | -7191 |
| NUP62 | -7186 |
| WASF2 | -7177 |
| CAPZB | -7174 |
| CFL1 | -7166 |
| LILRA6 | -7161 |
| CD74 | -7156 |
| SLC2A5 | -7149 |
| LCK | -7148 |
| RNF130 | -7143 |
| C4A | -7134 |
| ANXA2 | -7132 |
| CST3 | -7129 |
| TNFRSF1A | -7128 |
| NDUFC2 | -7108 |
| PSMD2 | -7104 |
| SOD1 | -7080 |
| PGM1 | -7071 |
| SEC61B | -7068 |
| LGMN | -7062 |
| ANAPC11 | -7053 |
| HLA-DOA | -7051 |
| AP2A1 | -7041 |
| MSN | -7031 |
| ATP6V0E1 | -7030 |
| HMOX2 | -7026 |
| ACLY | -7023 |
| PFKL | -7021 |
| IGHV3-11 | -7017 |
| RAP1GAP2 | -7015 |
| SIGLEC9 | -7013 |
| TALDO1 | -7011 |
| PYCARD | -7010 |
| MIF | -7006 |
| AAAS | -7005 |
| PIANP | -6992 |
| CR2 | -6990 |
| MPO | -6977 |
| PPP2R1A | -6964 |
| SIGLEC11 | -6957 |
| AP1S1 | -6952 |
| CD33 | -6926 |
| NCKIPSD | -6918 |
| PRKCD | -6909 |
| UBA52 | -6880 |
| CD28 | -6879 |
| CYSTM1 | -6875 |
| AZU1 | -6868 |
| TCIRG1 | -6863 |
| RAC2 | -6835 |
| SNAP29 | -6830 |
| MYO9B | -6808 |
| EPX | -6806 |
| IL10RB | -6805 |
| VCAM1 | -6799 |
| S100A1 | -6798 |
| PRDX4 | -6797 |
| SIRPA | -6788 |
| PTPN9 | -6784 |
| PJA1 | -6781 |
| RNF126 | -6777 |
| CD300C | -6768 |
| ENPP4 | -6759 |
| RHOA | -6754 |
| ARPC4 | -6731 |
| MAVS | -6723 |
| LAG3 | -6722 |
| PITPNA | -6715 |
| PSMB6 | -6709 |
| FUCA1 | -6706 |
| RAB5C | -6693 |
| DYNLL2 | -6690 |
| CALR | -6689 |
| ISG15 | -6682 |
| HLA-DPB1 | -6679 |
| PYGB | -6678 |
| RPS6KA1 | -6676 |
| TREX1 | -6675 |
| MYH2 | -6671 |
| HSPA8 | -6665 |
| DNAJC5 | -6663 |
| PSMB3 | -6647 |
| LAMTOR2 | -6641 |
| FBXW9 | -6624 |
| LAT2 | -6615 |
| BTK | -6612 |
| ELOB | -6600 |
| AP1M1 | -6596 |
| FBXO2 | -6574 |
| PIK3R1 | -6564 |
| RNF123 | -6560 |
| C3AR1 | -6548 |
| PTPRN2 | -6546 |
| PDZD11 | -6539 |
| NCAM1 | -6534 |
| NFAM1 | -6523 |
| PPIA | -6508 |
| IL12RB2 | -6490 |
| PTPN23 | -6484 |
| PTPN22 | -6481 |
| MT2A | -6469 |
| DYNLL1 | -6465 |
| C7 | -6464 |
| FTH1 | -6455 |
| TRIM62 | -6453 |
| PSMD4 | -6452 |
| KIF22 | -6434 |
| NUP88 | -6417 |
| CSF1 | -6415 |
| HLA-DRA | -6414 |
| NCF4 | -6412 |
| ATP6V0B | -6404 |
| RAB5B | -6400 |
| AOC1 | -6397 |
| BRI3 | -6394 |
| TRIM8 | -6390 |
| PRTN3 | -6386 |
| MUC6 | -6359 |
| LY86 | -6355 |
| TAB1 | -6350 |
| ACTR1A | -6346 |
| HLA-DPA1 | -6339 |
| PSMF1 | -6332 |
| MAPK3 | -6329 |
| FBXL15 | -6290 |
| PSEN1 | -6281 |
| ATP6V0A1 | -6280 |
| FCGR1B | -6274 |
| STXBP2 | -6273 |
| PDAP1 | -6258 |
| OTUD5 | -6256 |
| SEC61G | -6251 |
| GPI | -6235 |
| POM121 | -6233 |
| TNFSF12 | -6230 |
| TUBB4B | -6218 |
| SYK | -6217 |
| SIGLEC6 | -6204 |
| IGF2R | -6196 |
| UBB | -6193 |
| SLA | -6188 |
| MKRN1 | -6170 |
| CD14 | -6153 |
| BRK1 | -6144 |
| PSMC5 | -6143 |
| AP2A2 | -6118 |
| ATP6V0D1 | -6117 |
| RNF216 | -6107 |
| CCL5 | -6105 |
| SEC24C | -6100 |
| AIP | -6099 |
| TRBC1 | -6095 |
| P2RX1 | -6092 |
| PSMA7 | -6082 |
| SIGLEC8 | -6076 |
| AP2B1 | -6058 |
| PA2G4 | -6056 |
| SMAD3 | -6044 |
| INPPL1 | -6034 |
| ACTR1B | -6022 |
| TP53 | -6010 |
| PGAM1 | -6006 |
| TXNIP | -5982 |
| HVCN1 | -5979 |
| LGALS3 | -5963 |
| PSMB7 | -5953 |
| MYO1C | -5948 |
| TIMP2 | -5932 |
| UBE2L3 | -5910 |
| TLR5 | -5906 |
| RAB37 | -5902 |
| TRPM2 | -5896 |
| IL17RA | -5895 |
| VAMP2 | -5893 |
| MASP2 | -5892 |
| IL11RA | -5882 |
| NCKAP1L | -5878 |
| ELK1 | -5875 |
| NOS2 | -5871 |
| PSMC4 | -5866 |
| FBXO44 | -5864 |
| PRR5 | -5863 |
| RAB7A | -5854 |
| GAB2 | -5845 |
| TLR2 | -5828 |
| ARPC3 | -5798 |
| SPSB4 | -5797 |
| PPP2R5D | -5791 |
| CFD | -5789 |
| STBD1 | -5764 |
| CD70 | -5746 |
| RHOF | -5736 |
| PSMC3 | -5726 |
| UBAC1 | -5722 |
| UBE2F | -5708 |
| MMP1 | -5699 |
| ELMO2 | -5690 |
| PTGES2 | -5671 |
| FSCN1 | -5659 |
| TXLNA | -5656 |
| GSTO1 | -5648 |
| UBR4 | -5637 |
| SPSB2 | -5632 |
| IL21R | -5615 |
| TRIM21 | -5612 |
| IL10RA | -5599 |
| SDC1 | -5597 |
| PDXK | -5585 |
| LILRB1 | -5584 |
| ASB8 | -5552 |
| VRK3 | -5547 |
| RNF4 | -5526 |
| VCP | -5509 |
| ITPR3 | -5506 |
| NPC2 | -5501 |
| ICAM5 | -5497 |
| HLA-DMB | -5489 |
| PSMB1 | -5473 |
| DIAPH1 | -5472 |
| UNC13D | -5470 |
| NOD2 | -5469 |
| HEXB | -5455 |
| TRIM11 | -5415 |
| MLEC | -5382 |
| CD3E | -5364 |
| FAF2 | -5362 |
| CTSS | -5358 |
| CLEC4A | -5346 |
| NUP93 | -5327 |
| SLC15A4 | -5316 |
| RAET1E | -5308 |
| ACAA1 | -5304 |
| PRKCSH | -5301 |
| PRDX6 | -5286 |
| POLR3GL | -5285 |
| CD44 | -5281 |
| SH3GL2 | -5270 |
| ATOX1 | -5254 |
| COTL1 | -5238 |
| APP | -5231 |
| LCP2 | -5202 |
| UBE2L6 | -5197 |
| CD86 | -5191 |
| COLEC12 | -5183 |
| RNF25 | -5176 |
| PSMB4 | -5168 |
| MIB2 | -5157 |
| NUP37 | -5152 |
| XRCC6 | -5145 |
| OLR1 | -5138 |
| DOCK2 | -5130 |
| ASB6 | -5125 |
| BATF | -5115 |
| HECTD3 | -5103 |
| HLA-DMA | -5092 |
| PTPN1 | -5091 |
| NFKBIB | -5076 |
| ACTB | -5073 |
| POLR2L | -5071 |
| SERPING1 | -5070 |
| SEC22B | -5055 |
| KBTBD7 | -5035 |
| FBXL8 | -5033 |
| NME2 | -5012 |
| PTPN20 | -5002 |
| TIFA | -4991 |
| CTSL | -4981 |
| ERAP1 | -4972 |
| AMPD3 | -4970 |
| HRAS | -4955 |
| TNFRSF11A | -4942 |
| RBCK1 | -4932 |
| CD22 | -4929 |
| CFP | -4887 |
| GLIPR1 | -4882 |
| HAVCR2 | -4881 |
| UBE2Z | -4878 |
| TRAC | -4873 |
| FBXO41 | -4858 |
| FYN | -4854 |
| EVL | -4849 |
| QSOX1 | -4847 |
| AGPAT2 | -4846 |
| FLT3LG | -4803 |
| IL2RG | -4799 |
| TNFRSF12A | -4793 |
| KLHL41 | -4791 |
| GNS | -4788 |
| CPNE1 | -4785 |
| STAT4 | -4768 |
| ZBTB16 | -4763 |
| RACGAP1 | -4762 |
| NEU1 | -4756 |
| FCGR2A | -4754 |
| ARPC1A | -4752 |
| SERPINB6 | -4751 |
| UBE2E3 | -4749 |
| P2RX7 | -4748 |
| MASP1 | -4746 |
| VPS35L | -4738 |
| SKP1 | -4737 |
| LRR1 | -4728 |
| CD8A | -4727 |
| NEDD4L | -4722 |
| NUP188 | -4718 |
| C5AR2 | -4710 |
| DEFA4 | -4707 |
| IGKV1-33 | -4702 |
| ARPC2 | -4697 |
| MAP2K1 | -4692 |
| BPI | -4682 |
| FBXL18 | -4675 |
| CLTA | -4661 |
| LTF | -4657 |
| PSMD9 | -4655 |
| TRIM41 | -4653 |
| NF2 | -4649 |
| TNFRSF13C | -4646 |
| DDX41 | -4633 |
| TOM1 | -4624 |
| CA1 | -4616 |
| POLR3K | -4605 |
| ARL8A | -4561 |
| ATP6V1G1 | -4500 |
| LTA4H | -4460 |
| HUWE1 | -4455 |
| ECSIT | -4451 |
| TYK2 | -4442 |
| RBX1 | -4435 |
| TRIM35 | -4430 |
| SEC31A | -4403 |
| HSPA5 | -4392 |
| DCTN6 | -4386 |
| ATP6V1D | -4357 |
| DYNC1H1 | -4355 |
| HSP90B1 | -4345 |
| TLR9 | -4319 |
| LTBR | -4318 |
| TRAF2 | -4296 |
| SQSTM1 | -4289 |
| PLPP5 | -4285 |
| FCGR2B | -4271 |
| STAT5A | -4263 |
| VAMP3 | -4260 |
| PLAUR | -4209 |
| TICAM2 | -4199 |
| PLD4 | -4193 |
| PSMC2 | -4179 |
| GSN | -4173 |
| CD300LF | -4120 |
| POLR3D | -4118 |
| PTPN7 | -4113 |
| SAR1B | -4109 |
| LAT | -4104 |
| STK11IP | -4103 |
| C4B | -4099 |
| RELA | -4097 |
| CCND1 | -4087 |
| PSTPIP1 | -4077 |
| PKP1 | -4076 |
| IKBKE | -4068 |
| KLHL22 | -4065 |
| FBXO27 | -4047 |
| DEFA1 | -4036 |
| SERPINB1 | -4033 |
| FBXO7 | -4031 |
| PIK3AP1 | -4015 |
| SARM1 | -4011 |
| MGRN1 | -4002 |
| CTF1 | -4001 |
| GYG1 | -3994 |
| TRIM17 | -3980 |
| CCR1 | -3968 |
| NLRC4 | -3965 |
| SH2B1 | -3963 |
| CAP1 | -3949 |
| PRKACB | -3946 |
| ORAI2 | -3933 |
| TANK | -3918 |
| MANBA | -3901 |
| DNM2 | -3899 |
| ACP3 | -3897 |
| AGA | -3893 |
| POLR2F | -3890 |
| FBXO9 | -3877 |
| CDA | -3870 |
| CYBB | -3854 |
| PSMD10 | -3849 |
| TKFC | -3846 |
| BOLA2 | -3834 |
| BLK | -3800 |
| UBE2Q1 | -3785 |
| UNKL | -3770 |
| OSTF1 | -3768 |
| CRKL | -3767 |
| KPNA2 | -3765 |
| GSDME | -3760 |
| CTSF | -3736 |
| NLRC3 | -3735 |
| TRIB3 | -3731 |
| FGL2 | -3730 |
| EBI3 | -3712 |
| BIN2 | -3707 |
| TLR3 | -3698 |
| BLNK | -3695 |
| BTRC | -3694 |
| HLA-A | -3688 |
| MAGT1 | -3673 |
| AP1S2 | -3655 |
| RAP2B | -3635 |
| PELI3 | -3632 |
| CDC20 | -3613 |
| NUP214 | -3603 |
| RNF7 | -3583 |
| JUP | -3580 |
| RAF1 | -3561 |
| CCR2 | -3535 |
| CD96 | -3514 |
| VASP | -3497 |
| IQGAP2 | -3492 |
| UBE2E2 | -3486 |
| SIGLEC10 | -3480 |
| ASB5 | -3435 |
| IL18 | -3383 |
| ANAPC2 | -3380 |
| TRAF3 | -3366 |
| TMC6 | -3356 |
| RAC1 | -3331 |
| ASAH1 | -3322 |
| PPIE | -3321 |
| PLD1 | -3314 |
| PAK1 | -3309 |
| CD19 | -3284 |
| LPCAT1 | -3282 |
| RNF34 | -3270 |
| POLR2K | -3261 |
| CAMP | -3260 |
| IDH1 | -3258 |
| PSMA6 | -3225 |
| CDC42 | -3206 |
| STX4 | -3195 |
| ATP6AP2 | -3183 |
| ITGA4 | -3150 |
| ATP6V1E1 | -3137 |
| CCNF | -3122 |
| LY96 | -3104 |
| SMARCA4 | -3100 |
| RAE1 | -3056 |
| CDC26 | -3045 |
| UBE2V2 | -3043 |
| TXK | -3035 |
| PSME1 | -3031 |
| NUP98 | -3024 |
| TXN | -3012 |
| FLNB | -3001 |
| KCMF1 | -2999 |
| PTPRJ | -2991 |
| FBXO6 | -2980 |
| RAB44 | -2971 |
| TRIM4 | -2969 |
| FOXO3 | -2967 |
| LAMP2 | -2955 |
| TRIM29 | -2952 |
| RAPGEF1 | -2950 |
| C1R | -2949 |
| FCGR1A | -2944 |
| LNX1 | -2928 |
| EDARADD | -2894 |
| LYN | -2889 |
| RPLP0 | -2877 |
| IL13RA1 | -2873 |
| SRP14 | -2850 |
| AREL1 | -2834 |
| CRCP | -2833 |
| MAPKAP1 | -2829 |
| MYLIP | -2823 |
| CREBBP | -2822 |
| CASP9 | -2821 |
| FLNA | -2819 |
| IL23A | -2796 |
| FOXO1 | -2775 |
| ELMO1 | -2743 |
| ARSB | -2736 |
| UBE2D2 | -2735 |
| PSMD7 | -2731 |
| CR1 | -2725 |
| FBXO4 | -2716 |
| PPP2R5B | -2711 |
| LTB | -2710 |
| EEF2 | -2697 |
| AGL | -2689 |
| WIPF2 | -2680 |
| PSMA5 | -2649 |
| ATP6V1B2 | -2647 |
| TNFSF11 | -2641 |
| ITGAX | -2635 |
| MMP9 | -2629 |
| PSMC1 | -2604 |
| CD3D | -2603 |
| STAT6 | -2573 |
| SIGIRR | -2572 |
| RASGRP2 | -2558 |
| CYFIP2 | -2546 |
| S100A8 | -2515 |
| C5AR1 | -2504 |
| CLTC | -2500 |
| ITGAV | -2473 |
| GZMM | -2461 |
| KLRB1 | -2458 |
| ADAM8 | -2446 |
| ANAPC7 | -2426 |
| CCR5 | -2425 |
| IFI35 | -2416 |
| SPSB1 | -2411 |
| FBXW11 | -2408 |
| GHR | -2406 |
| KIF2A | -2396 |
| C6orf120 | -2385 |
| IP6K2 | -2378 |
| POLR3C | -2369 |
| FZR1 | -2354 |
| PPP2CB | -2329 |
| HGSNAT | -2328 |
| TNFRSF13B | -2309 |
| FBXO17 | -2307 |
| IST1 | -2289 |
| ZNRF1 | -2287 |
| POLR3A | -2280 |
| UBA7 | -2276 |
| IRF3 | -2274 |
| EDA2R | -2266 |
| ARIH2 | -2260 |
| TLR4 | -2238 |
| PTAFR | -2233 |
| SH3KBP1 | -2230 |
| SIGLEC15 | -2223 |
| NUP85 | -2218 |
| STAT3 | -2208 |
| CTSO | -2186 |
| PIAS1 | -2173 |
| TNIP2 | -2170 |
| POLR2H | -2169 |
| PCBP2 | -2168 |
| PTPRC | -2154 |
| PSMD14 | -2133 |
| KLC1 | -2130 |
| CLEC7A | -2119 |
| CD40 | -2074 |
| MAOA | -2073 |
| IL1RL2 | -2062 |
| HLA-DQB2 | -2038 |
| RNASEL | -2035 |
| HCST | -2012 |
| KLHL11 | -2004 |
| MAP3K14 | -1995 |
| B2M | -1976 |
| HLA-DRB1 | -1973 |
| KBTBD6 | -1943 |
| FBXO40 | -1930 |
| RIPK1 | -1922 |
| NDC1 | -1920 |
| RAG1 | -1904 |
| SYNGR1 | -1890 |
| DGAT1 | -1889 |
| NFATC3 | -1875 |
| ATAD3B | -1816 |
| HPSE | -1810 |
| CAB39 | -1802 |
| PSMD1 | -1782 |
| LILRA5 | -1773 |
| DEGS1 | -1772 |
| LAMTOR3 | -1758 |
| PSMA4 | -1756 |
| TRIM2 | -1749 |
| ELANE | -1741 |
| AGER | -1738 |
| UBE2O | -1729 |
| IRF2 | -1715 |
| MAP2K3 | -1696 |
| IFNAR1 | -1680 |
| PTK2B | -1670 |
| CYFIP1 | -1658 |
| IMPDH2 | -1641 |
| IL16 | -1635 |
| TIRAP | -1629 |
| ABL1 | -1625 |
| EEF1A1 | -1605 |
| PSME2 | -1591 |
| TRAIP | -1589 |
| TLR8 | -1571 |
| KLHL9 | -1561 |
| ANAPC10 | -1560 |
| TRIM50 | -1554 |
| TNFRSF25 | -1544 |
| UBOX5 | -1536 |
| GDI2 | -1535 |
| LRSAM1 | -1533 |
| RAB9B | -1509 |
| C1S | -1499 |
| NCR3LG1 | -1489 |
| PSMD11 | -1483 |
| SPTAN1 | -1454 |
| CFI | -1444 |
| PSMD5 | -1433 |
| RAB10 | -1385 |
| CISH | -1383 |
| SOD2 | -1375 |
| ANAPC5 | -1362 |
| MUC1 | -1357 |
| NCF2 | -1349 |
| TOMM70 | -1316 |
| CTSH | -1301 |
| PSMA2 | -1286 |
| IL2RB | -1284 |
| FGF2 | -1269 |
| FBXW4 | -1204 |
| MAPK14 | -1200 |
| CTSC | -1185 |
| RNF114 | -1182 |
| ILF2 | -1166 |
| SEC24D | -1154 |
| RNF41 | -1144 |
| ATP6V0A2 | -1143 |
| ERP44 | -1134 |
| CFH | -1103 |
| PGRMC1 | -1094 |
| CDC23 | -1090 |
| KIF3B | -1084 |
| DHX9 | -1082 |
| MUC12 | -1066 |
| SH2B3 | -1037 |
| CREG1 | -1028 |
| FBXL19 | -1026 |
| IQGAP1 | -1025 |
| ARHGAP9 | -1009 |
| FBXO10 | -1005 |
| STK10 | -977 |
| ARPC5 | -969 |
| ACTG1 | -959 |
| MRC1 | -943 |
| PTPN12 | -930 |
| CARD11 | -915 |
| COPB1 | -893 |
| ALAD | -888 |
| LCN2 | -875 |
| FBXL5 | -865 |
| PROS1 | -863 |
| ORAI1 | -844 |
| VAV2 | -840 |
| ZNRF2 | -837 |
| CD247 | -834 |
| CBLB | -823 |
| PRLR | -820 |
| HLA-H | -815 |
| RASGRP1 | -813 |
| ADAM10 | -804 |
| CDC34 | -803 |
| CAPZA2 | -802 |
| PPP3CB | -797 |
| PSMD13 | -754 |
| YPEL5 | -739 |
| NUP205 | -738 |
| TRIP12 | -687 |
| B4GALT1 | -661 |
| VAMP7 | -643 |
| NUP42 | -641 |
| PTPRZ1 | -635 |
| TRIM63 | -624 |
| PIK3R4 | -607 |
| RAB31 | -572 |
| MTOR | -561 |
| COL1A2 | -557 |
| CANX | -540 |
| TRIM34 | -539 |
| UBE2G2 | -536 |
| TLR1 | -517 |
| AHCYL1 | -485 |
| NFATC1 | -480 |
| RBSN | -469 |
| CPNE3 | -465 |
| UBE2R2 | -460 |
| COLEC11 | -449 |
| TNFSF8 | -447 |
| IFITM3 | -435 |
| UBE2K | -426 |
| POLR3B | -417 |
| ZAP70 | -398 |
| UBE3B | -397 |
| ACTR10 | -373 |
| DHX58 | -345 |
| SOCS6 | -332 |
| FBXO21 | -329 |
| TMEM63A | -321 |
| CTSG | -319 |
| VIM | -308 |
| DTX3L | -291 |
| CRACR2A | -287 |
| SH2D1A | -253 |
| EP300 | -244 |
| PSMB8 | -235 |
| CDK13 | -219 |
| RNF14 | -201 |
| OSMR | -195 |
| XRCC5 | -190 |
| RNF6 | -166 |
| NUP153 | -156 |
| DUSP7 | -150 |
| HLA-DQA2 | -146 |
| CMTM6 | -131 |
| PRKDC | -116 |
| RAP1A | -109 |
| NFKBIE | -108 |
| PIK3CB | -106 |
| TBC1D10C | -97 |
| CASP2 | -84 |
| TNFSF4 | -75 |
| TNFRSF6B | -72 |
| CD300LB | -68 |
| TRIM3 | -67 |
| CCR6 | -53 |
| PSME4 | -48 |
| IL11 | -43 |
| CCT2 | -39 |
| CAMK2B | -37 |
| IRF8 | -34 |
| WIPF1 | 21 |
| PSMD6 | 26 |
| PYGL | 29 |
| PDPK1 | 33 |
| KIF15 | 35 |
| DEFA3 | 43 |
| DCTN4 | 48 |
| UFL1 | 62 |
| TRIM39 | 83 |
| AP1G1 | 107 |
| CXADR | 117 |
| IRF9 | 144 |
| ATP8A1 | 145 |
| STAT2 | 146 |
| CD58 | 163 |
| TAX1BP1 | 167 |
| NFKBIA | 181 |
| UBE4A | 191 |
| IL20RB | 192 |
| PPP2R5C | 198 |
| POLR1C | 223 |
| RPS27A | 229 |
| UBE3C | 236 |
| KIF5A | 259 |
| ATP11A | 281 |
| KCTD7 | 290 |
| ATP6V1G2 | 311 |
| UBE2G1 | 327 |
| KBTBD8 | 348 |
| FBXL13 | 359 |
| TRIM69 | 367 |
| TLR6 | 378 |
| PSMA1 | 379 |
| MYO5A | 391 |
| PRKCB | 421 |
| TICAM1 | 465 |
| UBE2A | 466 |
| FRMPD3 | 485 |
| CAMK2A | 491 |
| DYNLT1 | 501 |
| NFKB1 | 503 |
| IL17RE | 520 |
| POLR3E | 523 |
| TEC | 533 |
| C5 | 536 |
| CCL19 | 547 |
| NHLRC3 | 550 |
| SAA1 | 558 |
| CDC16 | 578 |
| LCP1 | 579 |
| TRIM36 | 600 |
| CPPED1 | 613 |
| C4BPB | 614 |
| CLEC5A | 625 |
| NCK1 | 629 |
| CD226 | 648 |
| VHL | 652 |
| GOLGA7 | 702 |
| IFI6 | 705 |
| ANXA1 | 709 |
| SNRPA1 | 765 |
| MGST1 | 767 |
| MAP2K4 | 772 |
| RAB4B | 790 |
| MAPK13 | 792 |
| KLHL25 | 799 |
| RAP1B | 813 |
| THEM4 | 832 |
| POLR1D | 855 |
| PPP3CA | 858 |
| RAB18 | 879 |
| MAP3K3 | 883 |
| PML | 912 |
| ATP6V1H | 924 |
| TRAF7 | 930 |
| SEC23A | 932 |
| MAPKAPK2 | 933 |
| DERA | 944 |
| EEA1 | 975 |
| ACTR2 | 1000 |
| CASP1 | 1004 |
| STAT1 | 1015 |
| ADAR | 1042 |
| COMMD3 | 1045 |
| INPP5D | 1076 |
| STIM1 | 1087 |
| KIF20A | 1125 |
| STING1 | 1130 |
| BST1 | 1165 |
| CD200R1 | 1185 |
| SOCS1 | 1191 |
| TNFRSF9 | 1198 |
| TRIM56 | 1246 |
| HLA-DOB | 1253 |
| FBXL3 | 1274 |
| FBXL14 | 1285 |
| CD274 | 1301 |
| MAP3K7 | 1306 |
| ASB7 | 1320 |
| POLR3G | 1321 |
| KLRG1 | 1337 |
| EDA | 1354 |
| IL6ST | 1364 |
| DNAJC3 | 1382 |
| PJA2 | 1387 |
| UBE3A | 1402 |
| DET1 | 1405 |
| CUL1 | 1406 |
| EIF4A1 | 1415 |
| HSP90AB1 | 1424 |
| ICAM3 | 1443 |
| RORC | 1445 |
| PIK3CD | 1455 |
| YWHAB | 1469 |
| PLA2G2A | 1477 |
| PRCP | 1478 |
| PPP2R5E | 1485 |
| S100A9 | 1503 |
| PAFAH1B2 | 1516 |
| IL7R | 1521 |
| GBP3 | 1524 |
| KPNA4 | 1528 |
| TNFRSF14 | 1533 |
| CD47 | 1536 |
| UBE2E1 | 1544 |
| SAMHD1 | 1554 |
| RNF213 | 1560 |
| ICAM2 | 1582 |
| RHOU | 1597 |
| MAPK1 | 1610 |
| EIF4G2 | 1614 |
| CALM1 | 1638 |
| KPNA1 | 1641 |
| SOS2 | 1678 |
| RBBP6 | 1706 |
| HLA-DRB5 | 1726 |
| KLC2 | 1731 |
| CAPZA1 | 1732 |
| UBE2N | 1734 |
| NRAS | 1742 |
| UBE2C | 1747 |
| PAK3 | 1749 |
| IKBKB | 1755 |
| FBXO22 | 1768 |
| GRAP2 | 1775 |
| ITGAL | 1798 |
| FBXL12 | 1810 |
| TAB2 | 1818 |
| RNF115 | 1854 |
| ATP11B | 1882 |
| RAB14 | 1901 |
| MME | 1917 |
| RAB24 | 1920 |
| TNFSF13B | 1925 |
| FBXW2 | 1926 |
| TRIM46 | 1932 |
| VAV3 | 1970 |
| CRK | 1993 |
| ICOSLG | 2001 |
| SCAMP1 | 2005 |
| TRIM45 | 2011 |
| TNFAIP6 | 2017 |
| ATP6V1A | 2025 |
| MMP8 | 2043 |
| IRF7 | 2060 |
| RAB6A | 2072 |
| NAPRT | 2077 |
| LILRA1 | 2083 |
| CLEC2D | 2089 |
| NUP155 | 2114 |
| KIF11 | 2120 |
| SMURF1 | 2127 |
| NUP35 | 2129 |
| UBE2B | 2133 |
| NUP54 | 2157 |
| PIK3CA | 2176 |
| FPR1 | 2178 |
| FBXW8 | 2188 |
| ATP8B4 | 2193 |
| TNF | 2195 |
| TRIM26 | 2204 |
| USP18 | 2206 |
| BTBD1 | 2212 |
| ATG5 | 2233 |
| CSF2RB | 2267 |
| TSPAN14 | 2269 |
| UBE2V1 | 2277 |
| PLD2 | 2287 |
| SMURF2 | 2303 |
| NCKAP1 | 2330 |
| TNFRSF18 | 2338 |
| CTLA4 | 2340 |
| LTN1 | 2367 |
| FKBP1A | 2371 |
| GSDMD | 2372 |
| ASB15 | 2375 |
| EIF4E | 2379 |
| KPNB1 | 2425 |
| MAPK9 | 2439 |
| RPS6KA2 | 2440 |
| NUP43 | 2453 |
| CD300E | 2454 |
| CASP3 | 2458 |
| YWHAZ | 2459 |
| RNF111 | 2478 |
| CHUK | 2486 |
| VTN | 2494 |
| FLT3 | 2506 |
| SUGT1 | 2512 |
| SIAH2 | 2522 |
| PAK2 | 2552 |
| POLR3F | 2553 |
| IL17RB | 2567 |
| DNAJC13 | 2644 |
| DYNC1LI2 | 2656 |
| IRF6 | 2670 |
| ASB16 | 2681 |
| PVR | 2719 |
| UBE3D | 2733 |
| TNFRSF8 | 2734 |
| IL1RAP | 2804 |
| CYLD | 2838 |
| HERC2 | 2845 |
| FBXL4 | 2850 |
| IFIH1 | 2853 |
| ATP6V1C1 | 2865 |
| IFIT5 | 2869 |
| TNFRSF1B | 2872 |
| BLMH | 2879 |
| TLR7 | 2925 |
| RALA | 2932 |
| IL7 | 2937 |
| RNF144B | 2958 |
| WASF3 | 2959 |
| GLA | 2965 |
| JAK2 | 2971 |
| C3 | 2977 |
| WWP1 | 2981 |
| IFITM1 | 2988 |
| CCT8 | 3002 |
| TMEM30A | 3034 |
| BCL2 | 3041 |
| IRS1 | 3060 |
| HECTD2 | 3077 |
| KCTD6 | 3088 |
| BTN3A3 | 3091 |
| MEF2A | 3106 |
| IFNAR2 | 3115 |
| ATP6V1E2 | 3118 |
| C6 | 3124 |
| GMFG | 3137 |
| KIF2C | 3143 |
| FBXO30 | 3156 |
| ATF1 | 3170 |
| RANBP2 | 3171 |
| NLRP1 | 3172 |
| HSPA9 | 3176 |
| IL18BP | 3184 |
| DYNC1I2 | 3198 |
| KLHL20 | 3230 |
| DUSP6 | 3235 |
| UBC | 3246 |
| MAPK12 | 3258 |
| ELOC | 3260 |
| HECTD1 | 3278 |
| DAPP1 | 3291 |
| BST2 | 3310 |
| CD40LG | 3313 |
| CFHR3 | 3314 |
| CUL5 | 3316 |
| IFNGR1 | 3321 |
| TRIM6 | 3330 |
| ABI2 | 3335 |
| ACTR3 | 3346 |
| HNRNPF | 3367 |
| CREB1 | 3370 |
| ANO6 | 3372 |
| KLHL13 | 3381 |
| CHI3L1 | 3386 |
| ATP6V0D2 | 3413 |
| UBA3 | 3420 |
| PTPN14 | 3435 |
| VAPA | 3437 |
| SLA2 | 3440 |
| CBL | 3452 |
| PIK3C3 | 3477 |
| PILRB | 3491 |
| NIT2 | 3498 |
| CENPE | 3506 |
| CASP8 | 3510 |
| PPP2CA | 3519 |
| TAP2 | 3546 |
| CD101 | 3558 |
| MMP2 | 3573 |
| SEC24A | 3580 |
| ATP7A | 3594 |
| SVIP | 3595 |
| MAP3K1 | 3619 |
| CAT | 3646 |
| PSMD12 | 3658 |
| UBE2J1 | 3661 |
| NUP133 | 3662 |
| BIRC2 | 3674 |
| CUL2 | 3685 |
| PTX3 | 3686 |
| HSP90AA1 | 3693 |
| DSN1 | 3697 |
| HEBP2 | 3703 |
| PTPN11 | 3742 |
| UBE2D3 | 3753 |
| BTN3A2 | 3788 |
| PSMC6 | 3801 |
| DHX36 | 3817 |
| KIF5B | 3823 |
| SLC44A2 | 3834 |
| HGF | 3844 |
| NLRP3 | 3857 |
| ROCK1 | 3867 |
| RPS6KA3 | 3890 |
| KRAS | 3903 |
| KPNA3 | 3912 |
| CCL3 | 3919 |
| PADI2 | 3928 |
| SEC24B | 3945 |
| ATF2 | 3946 |
| CEACAM3 | 3957 |
| NFASC | 3959 |
| SUMO1 | 3974 |
| NPEPPS | 3979 |
| NFATC2 | 3997 |
| ASB2 | 4032 |
| ITPR2 | 4036 |
| IRAK3 | 4043 |
| ABI1 | 4070 |
| PRKCQ | 4076 |
| CAND1 | 4089 |
| UBE2Q2 | 4114 |
| PSMB9 | 4121 |
| PLAU | 4122 |
| IL27RA | 4125 |
| ISG20 | 4138 |
| DUSP3 | 4149 |
| TCP1 | 4158 |
| MTAP | 4167 |
| FBXO32 | 4176 |
| KLHL2 | 4179 |
| TAB3 | 4183 |
| HMOX1 | 4200 |
| ENAH | 4229 |
| IL32 | 4241 |
| ABCE1 | 4250 |
| MYH9 | 4253 |
| CD3G | 4272 |
| CFHR1 | 4275 |
| NBEAL2 | 4305 |
| SHC1 | 4317 |
| KIF3C | 4321 |
| SEH1L | 4352 |
| BTN2A2 | 4378 |
| ANAPC1 | 4391 |
| IRF4 | 4395 |
| UBA6 | 4398 |
| FBXL20 | 4403 |
| IL22RA1 | 4441 |
| PTPN2 | 4448 |
| CDC27 | 4464 |
| HERC4 | 4466 |
| PPBP | 4468 |
| NUP58 | 4488 |
| MOSPD2 | 4491 |
| AIM2 | 4492 |
| NFKB2 | 4495 |
| ATG12 | 4504 |
| CEBPD | 4516 |
| ADAM17 | 4517 |
| ITGB1 | 4542 |
| TSLP | 4550 |
| LNPEP | 4556 |
| ASB14 | 4566 |
| IFI27 | 4568 |
| PTPN13 | 4569 |
| TRIM38 | 4584 |
| GBP5 | 4593 |
| CUL3 | 4595 |
| IL18R1 | 4597 |
| CLCF1 | 4607 |
| FBXL7 | 4619 |
| JAK1 | 4640 |
| TNFSF15 | 4662 |
| CD46 | 4669 |
| EIF4A3 | 4673 |
| FBXW12 | 4698 |
| OAS1 | 4750 |
| OAS2 | 4786 |
| HLA-E | 4804 |
| CD1C | 4814 |
| UBR2 | 4820 |
| PTPN4 | 4832 |
| HLA-B | 4836 |
| PPM1B | 4840 |
| KIF18A | 4869 |
| ANAPC13 | 4885 |
| WASL | 4892 |
| HERC1 | 4902 |
| MCEMP1 | 4906 |
| SLPI | 4921 |
| ASB9 | 4957 |
| SERPINA3 | 4964 |
| MAP3K8 | 4967 |
| KIF4A | 4972 |
| KLRK1 | 5011 |
| QPCT | 5017 |
| CASP4 | 5033 |
| PSMA3 | 5077 |
| RAP2C | 5100 |
| HP | 5104 |
| PDCD1LG2 | 5115 |
| LEAP2 | 5123 |
| EIF4G3 | 5127 |
| PLA2G6 | 5139 |
| IL1R1 | 5143 |
| SNAP23 | 5187 |
| IL10 | 5196 |
| OAS3 | 5227 |
| HLA-F | 5232 |
| PLAC8 | 5241 |
| NUP160 | 5248 |
| PAG1 | 5281 |
| LBP | 5292 |
| HMGB1 | 5302 |
| SEC61A2 | 5305 |
| ARMC8 | 5310 |
| RELB | 5322 |
| RAB27A | 5323 |
| UBE2H | 5344 |
| RCHY1 | 5346 |
| SH3RF1 | 5370 |
| SEM1 | 5372 |
| UBE2S | 5380 |
| CCL4 | 5393 |
| OLFM4 | 5408 |
| UBE2D1 | 5427 |
| DZIP3 | 5436 |
| AKT3 | 5437 |
| PANX1 | 5438 |
| GBP2 | 5440 |
| FBXO11 | 5446 |
| SOS1 | 5452 |
| IL1RL1 | 5460 |
| CIITA | 5470 |
| IFITM2 | 5472 |
| BCL6 | 5505 |
| IRAK4 | 5507 |
| RAB3A | 5550 |
| MAPK8 | 5565 |
| PPP3R1 | 5668 |
| CNN2 | 5684 |
| SIKE1 | 5687 |
| PGM2 | 5693 |
| CEP290 | 5713 |
| SPTBN2 | 5752 |
| CTNNB1 | 5757 |
| NUP50 | 5758 |
| ITCH | 5770 |
| CTSK | 5776 |
| TPP2 | 5781 |
| HBB | 5795 |
| RLIM | 5796 |
| POU2F1 | 5828 |
| PLCG1 | 5830 |
| WASF1 | 5834 |
| PGLYRP1 | 5847 |
| PDE12 | 5862 |
| BTN3A1 | 5867 |
| ITK | 5899 |
| DOCK1 | 5903 |
| FCN3 | 5904 |
| STX3 | 5906 |
| IRAG2 | 5941 |
| SELL | 5962 |
| UBA5 | 5967 |
| RNF138 | 5981 |
| CD59 | 6004 |
| BIRC3 | 6018 |
| TRPC1 | 6031 |
| PNP | 6038 |
| GLMN | 6041 |
| EIF2AK2 | 6054 |
| DTX4 | 6069 |
| KIF3A | 6090 |
| ATP6V1B1 | 6096 |
| CD1D | 6125 |
| UBR1 | 6126 |
| MAP2K6 | 6128 |
| MICA | 6191 |
| DUSP4 | 6239 |
| CAMK2G | 6254 |
| CHIT1 | 6264 |
| PLEKHO2 | 6266 |
| DYNC1LI1 | 6270 |
| SOCS5 | 6321 |
| CEACAM1 | 6329 |
| GGH | 6348 |
| NEDD4 | 6379 |
| WIPF3 | 6386 |
| FBXW7 | 6440 |
| CRTAM | 6467 |
| LIFR | 6481 |
| NOS3 | 6496 |
| ULBP3 | 6532 |
| OPRD1 | 6572 |
| KIFAP3 | 6594 |
| NOD1 | 6632 |
| BRWD1 | 6639 |
| FBXO31 | 6642 |
| ALPK1 | 6672 |
| TRIM37 | 6681 |
| IFI16 | 6685 |
| MYO10 | 6688 |
| KLHL5 | 6693 |
| GAN | 6694 |
| NECTIN2 | 6697 |
| MALT1 | 6698 |
| HNRNPA2B1 | 6721 |
| CLEC10A | 6727 |
| CD79B | 6744 |
| PIK3R3 | 6755 |
| PRKCE | 6762 |
| RORA | 6791 |
| OSBPL1A | 6793 |
| IL34 | 6814 |
| IL13RA2 | 6825 |
| ZEB1 | 6849 |
| ICAM1 | 6879 |
| ANAPC4 | 6889 |
| MICB | 6901 |
| MRE11 | 6908 |
| EIF4A2 | 6916 |
| YES1 | 6926 |
| TRIM25 | 6947 |
| VNN1 | 6989 |
| PTEN | 7006 |
| ERAP2 | 7021 |
| ATP6V1C2 | 7031 |
| STAT5B | 7050 |
| EIF4E3 | 7054 |
| GBP4 | 7058 |
| IL20RA | 7064 |
| IL15 | 7066 |
| TAP1 | 7077 |
| NKIRAS1 | 7084 |
| LMO7 | 7131 |
| DEFB124 | 7136 |
| GATA3 | 7139 |
| TBK1 | 7169 |
| CXCL8 | 7197 |
| EGR1 | 7201 |
| ASB3 | 7208 |
| BTNL9 | 7224 |
| CD34 | 7230 |
| TRAF6 | 7237 |
| HIF1A | 7278 |
| VCL | 7281 |
| UBE2W | 7287 |
| TNFRSF4 | 7295 |
| MX1 | 7296 |
| BTN2A1 | 7334 |
| HERC6 | 7336 |
| SP100 | 7340 |
| KLRD1 | 7367 |
| SNAP25 | 7382 |
| RICTOR | 7399 |
| OSM | 7405 |
| KIF23 | 7413 |
| JAML | 7421 |
| KLHL42 | 7422 |
| GCA | 7447 |
| TRIM5 | 7449 |
| LRRFIP1 | 7451 |
| KLHL21 | 7460 |
| FRK | 7510 |
| SDCBP | 7519 |
| MEX3C | 7544 |
| CLEC12A | 7549 |
| AP1S3 | 7562 |
| IL4R | 7586 |
| RIPK3 | 7603 |
| OASL | 7645 |
| LMNB1 | 7662 |
| TRIM9 | 7667 |
| ZBP1 | 7679 |
| DYNC1I1 | 7687 |
| FPR2 | 7694 |
| DDX58 | 7734 |
| HLA-C | 7759 |
| IRS2 | 7770 |
| ASB4 | 7855 |
| SKP2 | 7870 |
| TREML2 | 7872 |
| CD160 | 7878 |
| CD300LG | 7880 |
| RAPGEF3 | 7895 |
| BCL2L11 | 7902 |
| MYC | 7937 |
| RSAD2 | 7951 |
| FCN1 | 7955 |
| ARIH1 | 7982 |
| TNFAIP3 | 8015 |
| REL | 8027 |
| DDX3X | 8042 |
| MEF2C | 8059 |
| CDH1 | 8078 |
| PTK2 | 8088 |
| LIF | 8094 |
| LAMA5 | 8121 |
| HNRNPDL | 8179 |
| IL15RA | 8187 |
| PPP2R5A | 8203 |
| IFIT3 | 8213 |
| RNF217 | 8239 |
| BCL10 | 8277 |
| IFIT1 | 8296 |
| CLEC4E | 8310 |
| MX2 | 8320 |
| IRAK2 | 8355 |
| ADGRE3 | 8356 |
| FBXL22 | 8385 |
| NLRC5 | 8445 |
| PPP2R1B | 8460 |
| FOS | 8474 |
| MID1 | 8480 |
| RPS6KA5 | 8492 |
| IRF1 | 8494 |
| TRIM22 | 8525 |
| PRKG1 | 8537 |
| CGAS | 8561 |
| RNF125 | 8568 |
| CLEC2B | 8571 |
| GBP1 | 8580 |
| CPN2 | 8591 |
| IL31RA | 8618 |
| CDKN1B | 8660 |
| CD36 | 8666 |
| FCER1A | 8672 |
| ABL2 | 8691 |
| TNFSF14 | 8697 |
| NPDC1 | 8705 |
| HECW2 | 8721 |
| PELI2 | 8729 |
| MNDA | 8733 |
| IL6R | 8757 |
| NOS1 | 8768 |
| S100A12 | 8800 |
| CTSV | 8815 |
| KPNA5 | 8837 |
| BIRC5 | 8840 |
| CSF3 | 8847 |
| HSPA6 | 8872 |
| HSPA1B | 8917 |
| MEFV | 8931 |
| RIPK2 | 8936 |
| GNLY | 8967 |
| FCAR | 8968 |
| PLCG2 | 8985 |
| PIM1 | 8989 |
| XAF1 | 9017 |
| S1PR1 | 9037 |
| LRG1 | 9040 |
| RNF19B | 9051 |
| GRB10 | 9089 |
| CAMK2D | 9106 |
| CSF3R | 9142 |
| A1BG | 9149 |
| IFIT2 | 9171 |
| RASGRP3 | 9229 |
| STOM | 9231 |
| NUP107 | 9235 |
| JUNB | 9236 |
| SOCS2 | 9251 |
| FABP5 | 9265 |
| PTPN5 | 9311 |
| FBXO15 | 9320 |
| OPRM1 | 9323 |
| S100P | 9326 |
| MAPK11 | 9361 |
| HTN1 | 9362 |
| APAF1 | 9365 |
| LRRC7 | 9375 |
| IL1B | 9376 |
| TNFSF9 | 9402 |
| SIAH1 | 9417 |
| KIF26A | 9425 |
| ITPR1 | 9487 |
| LONRF1 | 9493 |
| IL1R2 | 9540 |
| CASP10 | 9558 |
| PECAM1 | 9560 |
| JUN | 9573 |
| CRISPLD2 | 9598 |
| WSB1 | 9620 |
| VEGFA | 9645 |
| MUC3A | 9677 |
| PDCD4 | 9696 |
| MAPK10 | 9718 |
| IL33 | 9720 |
| KIF5C | 9732 |
| HERC3 | 9744 |
| MCL1 | 9752 |
| RNF19A | 9756 |
| CCL2 | 9784 |
| TWIST1 | 9796 |
| IL1RN | 9826 |
| KLHL3 | 9836 |
| CDKN1A | 9840 |
| DNM3 | 9866 |
| IL6 | 9872 |
| HERC5 | 9894 |
| CD93 | 9927 |
| PTGS2 | 9943 |
| RAPGEF4 | 9960 |
| MGAM | 9981 |
| HSPA1A | 9988 |
| IL18RAP | 10008 |
| SOCS3 | 10041 |
| HACE1 | 10068 |
| MMP25 | 10087 |
| DSP | 10097 |
| RNF182 | 10102 |
| PTPRB | 10103 |
| CXCR2 | 10117 |
| ADGRG3 | 10123 |
| CXCR1 | 10135 |
| CXCL2 | 10139 |
| IL3RA | 10141 |
| PELI1 | 10144 |
| FCGR3B | 10145 |
| CD200 | 10146 |
| SLC2A3 | 10153 |
Disease
| 302 | |
|---|---|
| set | Disease |
| setSize | 1446 |
| pANOVA | 2.05e-29 |
| s.dist | -0.177 |
| p.adjustANOVA | 5.94e-27 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| MUC20 | -9146 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| ABCC6 | -9135 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| MUC20 | -9146 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| ABCC6 | -9135 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| ADAMTSL5 | -9072 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| COMT | -9062 |
| IGKV3-20 | -9057 |
| ABCC2 | -9053 |
| SLC22A18 | -9051 |
| IGKV1-5 | -9049 |
| DERL3 | -9048 |
| AKT1S1 | -9040 |
| ALG3 | -9024 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| RPS26 | -8966 |
| FZD7 | -8965 |
| ABCD1 | -8964 |
| IGHV1-2 | -8953 |
| GPBAR1 | -8950 |
| CSF2RA | -8945 |
| GAA | -8936 |
| MLST8 | -8926 |
| SBSPON | -8920 |
| IGHV1-46 | -8910 |
| UBAP1 | -8894 |
| PC | -8891 |
| FGFR1 | -8888 |
| DPM2 | -8879 |
| SLC35C1 | -8876 |
| IGKV2D-28 | -8875 |
| IGHG4 | -8874 |
| CTSA | -8873 |
| P2RX4 | -8868 |
| CSK | -8867 |
| IGKV3-11 | -8864 |
| SEMA5A | -8863 |
| DOLK | -8850 |
| FMOD | -8843 |
| ST6GALNAC4 | -8835 |
| DAG1 | -8830 |
| IGKV1D-39 | -8828 |
| ATP1B1 | -8826 |
| NCSTN | -8815 |
| FGR | -8811 |
| IGLV3-21 | -8806 |
| SLC24A4 | -8803 |
| UNC93B1 | -8794 |
| PMM2 | -8777 |
| IGLV3-25 | -8773 |
| FN1 | -8771 |
| PIK3R2 | -8767 |
| CYBA | -8747 |
| CD4 | -8741 |
| NUP210 | -8727 |
| SLC35A2 | -8725 |
| BSG | -8711 |
| PTHLH | -8686 |
| KERA | -8680 |
| ABCA3 | -8664 |
| JAK3 | -8657 |
| SEC13 | -8653 |
| SLC29A3 | -8619 |
| NHLRC1 | -8617 |
| IGHV3-33 | -8608 |
| FOXO6 | -8604 |
| TUBB | -8597 |
| DHDDS | -8593 |
| WAS | -8588 |
| THSD4 | -8579 |
| IGLV2-14 | -8572 |
| GNB2 | -8571 |
| B4GAT1 | -8568 |
| RHBDF2 | -8567 |
| SIGMAR1 | -8563 |
| G6PC3 | -8561 |
| SDC3 | -8509 |
| PRKACA | -8490 |
| NCOR2 | -8458 |
| BTC | -8453 |
| AKT1 | -8448 |
| ATIC | -8444 |
| PSENEN | -8409 |
| HYAL1 | -8407 |
| RPN2 | -8394 |
| APBB1IP | -8393 |
| ATG7 | -8380 |
| ADAMTS15 | -8355 |
| FXYD6 | -8349 |
| PSMD3 | -8328 |
| AGTRAP | -8327 |
| GALK1 | -8324 |
| GPR84 | -8320 |
| TLN1 | -8319 |
| CTDP1 | -8295 |
| RHOG | -8288 |
| ADAMTS5 | -8283 |
| TGFB1 | -8281 |
| HCK | -8242 |
| CAPNS1 | -8240 |
| BCL2L1 | -8236 |
| SLC27A4 | -8235 |
| ADAMTS17 | -8231 |
| CD8B | -8225 |
| GANAB | -8218 |
| ALG12 | -8201 |
| GLB1 | -8189 |
| NELFB | -8176 |
| AP1B1 | -8173 |
| GSK3A | -8163 |
| PDCD1 | -8157 |
| DCTN1 | -8155 |
| MPDU1 | -8150 |
| PSMD8 | -8149 |
| SRC | -8148 |
| ZC3HC1 | -8146 |
| STRA6 | -8127 |
| SND1 | -8099 |
| ITGB3 | -8092 |
| IGLV1-40 | -8088 |
| PRELP | -8076 |
| RDH12 | -8061 |
| FCGR3A | -8055 |
| KREMEN1 | -8043 |
| RPS4X | -8028 |
| ALG1 | -8022 |
| IFNGR2 | -8015 |
| ENO1 | -8009 |
| MYD88 | -8007 |
| MBD3 | -8005 |
| GALNS | -7969 |
| FEN1 | -7968 |
| APH1A | -7954 |
| AP2M1 | -7945 |
| ACY1 | -7941 |
| ADAMTSL3 | -7925 |
| CAPN1 | -7920 |
| C1GALT1 | -7908 |
| BGN | -7906 |
| DDOST | -7902 |
| PTH1R | -7898 |
| POM121C | -7894 |
| POMC | -7890 |
| POLR2E | -7886 |
| MGAT1 | -7872 |
| ERBB2 | -7859 |
| TFDP2 | -7850 |
| BAIAP2 | -7839 |
| AP2S1 | -7829 |
| VAV1 | -7822 |
| DAD1 | -7820 |
| NT5E | -7815 |
| HMGA1 | -7808 |
| KEAP1 | -7807 |
| STX1A | -7794 |
| IMPDH1 | -7786 |
| POLR2J | -7782 |
| GOLGA2 | -7775 |
| TPR | -7773 |
| PRDX2 | -7763 |
| B3GALT6 | -7746 |
| HBEGF | -7744 |
| ARF1 | -7717 |
| PSMB10 | -7709 |
| MAP2K7 | -7697 |
| ADAMTSL4 | -7685 |
| SGSH | -7668 |
| SYVN1 | -7632 |
| EGFR | -7625 |
| PTGIR | -7623 |
| ARPC1B | -7593 |
| GPC6 | -7588 |
| PSMB5 | -7576 |
| FGF10 | -7555 |
| MUC4 | -7552 |
| RPN1 | -7545 |
| HK1 | -7518 |
| FADD | -7501 |
| KAT5 | -7497 |
| MOGS | -7465 |
| POLR2I | -7462 |
| VPS25 | -7443 |
| SLC7A7 | -7431 |
| GNAI2 | -7430 |
| PEBP1 | -7412 |
| GUSB | -7411 |
| IGKV3-15 | -7403 |
| TAF6 | -7386 |
| AKT2 | -7377 |
| IKBKG | -7367 |
| DVL1 | -7361 |
| FXYD2 | -7356 |
| FDX1 | -7349 |
| PTGER4 | -7331 |
| RRBP1 | -7313 |
| STT3A | -7290 |
| CCND2 | -7287 |
| PSME3 | -7280 |
| KIT | -7270 |
| PSMB2 | -7268 |
| SLC9A9 | -7265 |
| SV2B | -7256 |
| RBP4 | -7240 |
| GNG5 | -7218 |
| CYP26B1 | -7214 |
| EDEM2 | -7195 |
| OS9 | -7193 |
| GRB2 | -7191 |
| CDKN2A | -7189 |
| NUP62 | -7186 |
| FNTB | -7181 |
| WASF2 | -7177 |
| B3GAT3 | -7173 |
| CHMP2A | -7162 |
| ADAMTSL2 | -7159 |
| LCK | -7148 |
| GGCX | -7137 |
| PSMD2 | -7104 |
| SH3GL1 | -7094 |
| UBE2I | -7091 |
| TRIM27 | -7087 |
| PGM1 | -7071 |
| ANAPC11 | -7053 |
| AP2A1 | -7041 |
| MSN | -7031 |
| IGHV3-11 | -7017 |
| TALDO1 | -7011 |
| PYCARD | -7010 |
| AAAS | -7005 |
| CSPG4 | -7003 |
| SLC1A3 | -6985 |
| KHK | -6980 |
| PPP2R1A | -6964 |
| AP1S1 | -6952 |
| MGAT4B | -6946 |
| CHMP6 | -6927 |
| CHMP7 | -6920 |
| NCKIPSD | -6918 |
| CTBP1 | -6915 |
| SLC6A2 | -6913 |
| BRMS1 | -6900 |
| MC1R | -6886 |
| UBA52 | -6880 |
| CD28 | -6879 |
| CHMP1A | -6877 |
| VIPR2 | -6869 |
| BAD | -6859 |
| RAC2 | -6835 |
| CORO1A | -6828 |
| ADORA2B | -6827 |
| GNB1 | -6821 |
| ARRB2 | -6809 |
| MYO9B | -6808 |
| S100A1 | -6798 |
| GPC5 | -6778 |
| EXT2 | -6767 |
| LFNG | -6757 |
| TRADD | -6756 |
| ARPC4 | -6731 |
| HEXA | -6728 |
| C1QBP | -6720 |
| RMI2 | -6717 |
| RANGAP1 | -6714 |
| PSMB6 | -6709 |
| APOBEC3G | -6696 |
| DYNLL2 | -6690 |
| CALR | -6689 |
| ISG15 | -6682 |
| MYH2 | -6671 |
| DPAGT1 | -6669 |
| RNF5 | -6648 |
| PSMB3 | -6647 |
| MAP2K2 | -6638 |
| SNF8 | -6634 |
| PHB | -6626 |
| BTK | -6612 |
| ELOB | -6600 |
| AP1M1 | -6596 |
| SLC17A5 | -6589 |
| HDAC3 | -6566 |
| PIK3R1 | -6564 |
| PARP1 | -6552 |
| C3AR1 | -6548 |
| ADAMTS3 | -6521 |
| DPEP2 | -6514 |
| PPIA | -6508 |
| TBXAS1 | -6500 |
| BANF1 | -6497 |
| NELFE | -6491 |
| TPMT | -6473 |
| DYNLL1 | -6465 |
| PSMD4 | -6452 |
| NOTCH2 | -6449 |
| VPS4A | -6443 |
| DERL1 | -6431 |
| PRDX1 | -6420 |
| NUP88 | -6417 |
| GGT1 | -6408 |
| HGS | -6399 |
| RPL26L1 | -6364 |
| MUC6 | -6359 |
| AHCY | -6338 |
| SUPT4H1 | -6334 |
| PSMF1 | -6332 |
| MAPK3 | -6329 |
| PSEN1 | -6281 |
| POLR2G | -6267 |
| GNG7 | -6266 |
| POLR2C | -6264 |
| ALG2 | -6248 |
| P2RY11 | -6241 |
| POM121 | -6233 |
| H2BC12 | -6223 |
| B4GALT7 | -6219 |
| SYK | -6217 |
| CUX1 | -6213 |
| ADCY8 | -6200 |
| UBB | -6193 |
| PORCN | -6160 |
| ST3GAL1 | -6158 |
| CD14 | -6153 |
| BRK1 | -6144 |
| PSMC5 | -6143 |
| AP2A2 | -6118 |
| ADAMTS7 | -6113 |
| RPS6KB2 | -6103 |
| GPS2 | -6090 |
| PSMA7 | -6082 |
| AP2B1 | -6058 |
| SMAD3 | -6044 |
| NAGLU | -6035 |
| TAF12 | -6023 |
| CYP1B1 | -6012 |
| TP53 | -6010 |
| TXNIP | -5982 |
| RAD50 | -5975 |
| PSMB7 | -5953 |
| MYO1C | -5948 |
| TLR5 | -5906 |
| VAMP2 | -5893 |
| KLKB1 | -5881 |
| NCKAP1L | -5878 |
| ELK1 | -5875 |
| PGK1 | -5872 |
| NOS2 | -5871 |
| PSMC4 | -5866 |
| PRR5 | -5863 |
| TPST1 | -5860 |
| CHMP4B | -5859 |
| RAB7A | -5854 |
| NOXA1 | -5848 |
| GAB2 | -5845 |
| TLR2 | -5828 |
| OGG1 | -5816 |
| ARPC3 | -5798 |
| PPP2R5D | -5791 |
| ADAMTS16 | -5780 |
| RPL39L | -5767 |
| ADCY1 | -5762 |
| MAN1B1 | -5730 |
| PSMC3 | -5726 |
| GIPR | -5724 |
| ELMO2 | -5690 |
| TRIM28 | -5673 |
| HMG20B | -5672 |
| CP | -5647 |
| CDK5 | -5646 |
| SLC2A10 | -5602 |
| ARAF | -5600 |
| SDC1 | -5597 |
| CD163 | -5579 |
| VIPR1 | -5576 |
| POMGNT1 | -5565 |
| DBP | -5561 |
| ADCY9 | -5551 |
| POLA2 | -5538 |
| TCN2 | -5517 |
| FZD8 | -5516 |
| VCP | -5509 |
| CHST14 | -5507 |
| ITPR3 | -5506 |
| KSR1 | -5486 |
| PSMB1 | -5473 |
| GYS1 | -5458 |
| HEXB | -5455 |
| TSG101 | -5436 |
| AXIN1 | -5355 |
| NUP93 | -5327 |
| PRKCSH | -5301 |
| SLC4A1 | -5277 |
| SH3GL2 | -5270 |
| RPS14 | -5234 |
| APP | -5231 |
| GALE | -5230 |
| BTD | -5228 |
| CD86 | -5191 |
| POMT2 | -5184 |
| IDUA | -5179 |
| VPS28 | -5178 |
| PSMB4 | -5168 |
| MIB2 | -5157 |
| NUP37 | -5152 |
| XRCC6 | -5145 |
| GTF2E2 | -5131 |
| DOCK2 | -5130 |
| FURIN | -5098 |
| ACTB | -5073 |
| POLR2L | -5071 |
| SERPING1 | -5070 |
| DAXX | -5069 |
| PACS1 | -5061 |
| SLC20A2 | -5051 |
| MPI | -5037 |
| RAMP1 | -5032 |
| EREG | -5006 |
| CTSL | -4981 |
| HRAS | -4955 |
| CCND3 | -4943 |
| SLC25A4 | -4920 |
| GNAS | -4913 |
| RPL27 | -4912 |
| RPL27A | -4896 |
| CFP | -4887 |
| GP1BA | -4868 |
| FYN | -4854 |
| RNF185 | -4812 |
| FLT3LG | -4803 |
| GNS | -4788 |
| HDAC11 | -4782 |
| GTF2F1 | -4776 |
| ADAMTS10 | -4774 |
| SDC2 | -4765 |
| NEU1 | -4756 |
| FCGR2A | -4754 |
| ARPC1A | -4752 |
| P2RX7 | -4748 |
| RPL35 | -4745 |
| SKP1 | -4737 |
| NEDD4L | -4722 |
| NUP188 | -4718 |
| SLC26A2 | -4703 |
| IGKV1-33 | -4702 |
| ARPC2 | -4697 |
| MAP2K1 | -4692 |
| GLP2R | -4667 |
| CDK4 | -4665 |
| CLTA | -4661 |
| LTF | -4657 |
| PSMD9 | -4655 |
| FAU | -4625 |
| SLC2A9 | -4586 |
| TPST2 | -4585 |
| GNB3 | -4560 |
| SLC39A4 | -4543 |
| VAMP1 | -4493 |
| KREMEN2 | -4484 |
| TYK2 | -4442 |
| RBX1 | -4435 |
| SEC31A | -4403 |
| FXYD1 | -4365 |
| DYNC1H1 | -4355 |
| EGF | -4342 |
| TFG | -4337 |
| NMT1 | -4325 |
| TLR9 | -4319 |
| SPRED2 | -4302 |
| TRAF2 | -4296 |
| PAPSS2 | -4292 |
| SQSTM1 | -4289 |
| STAT5A | -4263 |
| PAPSS1 | -4246 |
| MMACHC | -4234 |
| THBS2 | -4197 |
| PSEN2 | -4195 |
| GTF2H4 | -4181 |
| PSMC2 | -4179 |
| POMT1 | -4165 |
| RPL13 | -4148 |
| LMBRD1 | -4140 |
| DVL2 | -4117 |
| RELA | -4097 |
| CCND1 | -4087 |
| PSTPIP1 | -4077 |
| CYP21A2 | -4060 |
| PPP1CC | -4053 |
| RPL8 | -4049 |
| RPS18 | -4032 |
| RPS10 | -4028 |
| PIK3AP1 | -4015 |
| RPS29 | -4009 |
| ABCB6 | -4003 |
| FGF1 | -3995 |
| GYG1 | -3994 |
| DPM3 | -3983 |
| GALNT12 | -3979 |
| CCNK | -3961 |
| PRKACB | -3946 |
| FGF9 | -3940 |
| VPS33B | -3938 |
| POLR2F | -3890 |
| SAP18 | -3880 |
| SLC37A4 | -3875 |
| RPS21 | -3873 |
| RANBP1 | -3860 |
| PSMD10 | -3849 |
| NEURL1 | -3848 |
| FDX2 | -3811 |
| MCCC2 | -3793 |
| KPNA2 | -3765 |
| GSDME | -3760 |
| CDC25B | -3759 |
| RPS5 | -3741 |
| ANAPC16 | -3739 |
| GSS | -3721 |
| CHST3 | -3720 |
| SDC4 | -3718 |
| BIN2 | -3707 |
| TLR3 | -3698 |
| BTRC | -3694 |
| HLA-A | -3688 |
| MAGT1 | -3673 |
| AP1S2 | -3655 |
| EXT1 | -3644 |
| SLC11A2 | -3629 |
| NUP214 | -3603 |
| MGAT2 | -3597 |
| SLC1A1 | -3578 |
| ERLIN1 | -3577 |
| RPS11 | -3569 |
| RAF1 | -3561 |
| RPL15 | -3543 |
| GBE1 | -3532 |
| RPLP1 | -3524 |
| RPL36 | -3523 |
| TGFA | -3504 |
| ERLIN2 | -3485 |
| RPL4 | -3472 |
| TRIP11 | -3466 |
| SUPT5H | -3462 |
| MMAB | -3427 |
| DUSP10 | -3426 |
| CYP27B1 | -3398 |
| IL18 | -3383 |
| ANAPC2 | -3380 |
| H2BC5 | -3370 |
| TRAF3 | -3366 |
| ADAMTS2 | -3363 |
| RPL31 | -3359 |
| BRAP | -3347 |
| SSRP1 | -3338 |
| RAC1 | -3331 |
| SCTR | -3288 |
| CD19 | -3284 |
| RPL23 | -3274 |
| POLR2K | -3261 |
| IDH1 | -3258 |
| SLC22A5 | -3243 |
| SUPT16H | -3242 |
| HDAC6 | -3228 |
| PSMA6 | -3225 |
| TAF7 | -3214 |
| RPL10 | -3210 |
| H2AJ | -3209 |
| CDC42 | -3206 |
| RPS25 | -3191 |
| RPL7A | -3188 |
| ITGA4 | -3150 |
| EEF1G | -3124 |
| RAN | -3114 |
| MGAT5 | -3110 |
| RPL12 | -3105 |
| LY96 | -3104 |
| TXNRD1 | -3072 |
| RPL29 | -3065 |
| RAE1 | -3056 |
| CDC26 | -3045 |
| HRH2 | -3037 |
| RPS19 | -3032 |
| PSME1 | -3031 |
| GNGT2 | -3028 |
| NUP98 | -3024 |
| RPL30 | -3017 |
| TXN | -3012 |
| C1GALT1C1 | -2997 |
| RPL19 | -2986 |
| GTF2A2 | -2979 |
| RPS8 | -2974 |
| FRS3 | -2970 |
| FOXO3 | -2967 |
| FCGR1A | -2944 |
| CARS1 | -2934 |
| BRCA1 | -2933 |
| CDC25A | -2926 |
| OGN | -2906 |
| CAST | -2891 |
| LYN | -2889 |
| BECN1 | -2887 |
| RPL35A | -2878 |
| RPLP0 | -2877 |
| MAPKAP1 | -2829 |
| CREBBP | -2822 |
| CASP9 | -2821 |
| RFT1 | -2817 |
| AMN | -2799 |
| SRD5A3 | -2797 |
| FOXO1 | -2775 |
| DERL2 | -2770 |
| PDGFRA | -2769 |
| NTHL1 | -2744 |
| ELMO1 | -2743 |
| ARSB | -2736 |
| PSMD7 | -2731 |
| RPL18 | -2728 |
| CCNE1 | -2722 |
| RPL18A | -2719 |
| PPP2R5B | -2711 |
| RPL13A | -2708 |
| GP1BB | -2704 |
| EEF2 | -2697 |
| RPL38 | -2691 |
| WIPF2 | -2680 |
| RPS27 | -2657 |
| PSMA5 | -2649 |
| GOLGA4 | -2618 |
| MVB12B | -2605 |
| PSMC1 | -2604 |
| SPRED3 | -2562 |
| RPS17 | -2555 |
| CYFIP2 | -2546 |
| RBP1 | -2526 |
| S100A8 | -2515 |
| CLTC | -2500 |
| PARP6 | -2498 |
| RPS23 | -2494 |
| RPS15 | -2484 |
| ALG8 | -2436 |
| ANAPC7 | -2426 |
| CCR5 | -2425 |
| DCXR | -2407 |
| YWHAE | -2405 |
| RPL34 | -2389 |
| FZR1 | -2354 |
| ATP1A1 | -2352 |
| MVB12A | -2344 |
| CBX1 | -2341 |
| RPS3A | -2337 |
| PPP2CB | -2329 |
| HGSNAT | -2328 |
| RPL28 | -2326 |
| HTR7 | -2324 |
| TUSC3 | -2306 |
| PARP16 | -2282 |
| ADAMTS8 | -2265 |
| CD9 | -2242 |
| RPLP2 | -2239 |
| TLR4 | -2238 |
| SH3KBP1 | -2230 |
| NUP85 | -2218 |
| ABCA1 | -2212 |
| STAT3 | -2208 |
| HDAC4 | -2202 |
| SLC25A6 | -2184 |
| PCCB | -2182 |
| POLR2H | -2169 |
| MRAS | -2165 |
| NCOR1 | -2161 |
| SPRED1 | -2145 |
| PSMD14 | -2133 |
| RPL32 | -2131 |
| KLC1 | -2130 |
| FDXR | -2115 |
| AGRN | -2113 |
| TOP3A | -2109 |
| ADCYAP1 | -2101 |
| RPL3L | -2091 |
| RPL23A | -2081 |
| ADAMTS6 | -2079 |
| RPS12 | -2076 |
| MAOA | -2073 |
| RPS15A | -2051 |
| ZC3HAV1 | -2039 |
| RDH5 | -2022 |
| TSC2 | -2013 |
| TFDP1 | -2011 |
| LIG4 | -2008 |
| B2M | -1976 |
| VCAN | -1970 |
| TPM3 | -1969 |
| TAF10 | -1955 |
| CHMP4A | -1935 |
| FGFR3 | -1929 |
| RIPK1 | -1922 |
| CYP2R1 | -1921 |
| NDC1 | -1920 |
| BRD4 | -1907 |
| RNMT | -1883 |
| CD320 | -1842 |
| HDAC10 | -1841 |
| PSMD1 | -1782 |
| RPL10A | -1766 |
| PSMA4 | -1756 |
| NAPEPLD | -1754 |
| RPS20 | -1746 |
| SLC2A1 | -1743 |
| LUM | -1737 |
| RPL37A | -1736 |
| XRCC4 | -1735 |
| CDK9 | -1701 |
| MAP2K3 | -1696 |
| RPS28 | -1692 |
| POLR2D | -1681 |
| IFNAR1 | -1680 |
| ARRB1 | -1679 |
| CYFIP1 | -1658 |
| MUTYH | -1655 |
| GRSF1 | -1654 |
| RPS3 | -1643 |
| IMPDH2 | -1641 |
| FKBP4 | -1639 |
| KDM1A | -1631 |
| TIRAP | -1629 |
| ABL1 | -1625 |
| DNMT1 | -1609 |
| PSME2 | -1591 |
| CAPN2 | -1590 |
| ALG9 | -1588 |
| RPS7 | -1576 |
| SLC7A9 | -1575 |
| ALG11 | -1573 |
| FRS2 | -1570 |
| ANAPC10 | -1560 |
| RPL37 | -1517 |
| DUSP16 | -1486 |
| PSMD11 | -1483 |
| PSMD5 | -1433 |
| ERLEC1 | -1425 |
| CYP27A1 | -1397 |
| RPS24 | -1390 |
| HNRNPK | -1387 |
| E2F1 | -1381 |
| SOD2 | -1375 |
| HLCS | -1371 |
| ANAPC5 | -1362 |
| MUC1 | -1357 |
| SAP30L | -1337 |
| PSMA2 | -1286 |
| RPL3 | -1283 |
| FGF2 | -1269 |
| GFPT1 | -1256 |
| RPS6 | -1245 |
| ADAMTS14 | -1232 |
| SIN3A | -1221 |
| MAPK14 | -1200 |
| ANAPC15 | -1199 |
| RMI1 | -1126 |
| GATAD2A | -1107 |
| CDC23 | -1090 |
| ATP1A2 | -1079 |
| MUC12 | -1066 |
| ADAMTS13 | -1058 |
| RPL26 | -1044 |
| IQGAP1 | -1025 |
| ADCY7 | -1010 |
| STX1B | -1007 |
| WDCP | -985 |
| ARPC5 | -969 |
| HDAC5 | -960 |
| ACTG1 | -959 |
| MRC1 | -943 |
| PTPN12 | -930 |
| RPL21 | -907 |
| PRIM1 | -905 |
| POLR2B | -873 |
| NELFA | -866 |
| GCKR | -862 |
| CHST6 | -856 |
| RPL11 | -848 |
| VAV2 | -840 |
| CD247 | -834 |
| GOLGB1 | -831 |
| F8 | -828 |
| RPL41 | -812 |
| SLC25A5 | -807 |
| PRKAR1B | -805 |
| ADAM10 | -804 |
| ACAN | -799 |
| KLB | -776 |
| PRMT1 | -759 |
| PSMD13 | -754 |
| NUP205 | -738 |
| OPLAH | -709 |
| MAP1LC3B | -706 |
| B4GALT1 | -661 |
| MSH3 | -648 |
| NUP42 | -641 |
| ADAMTS19 | -636 |
| MMUT | -618 |
| MTA2 | -616 |
| RPL17 | -614 |
| GTF2H3 | -612 |
| PIK3R4 | -607 |
| HDAC1 | -580 |
| MTOR | -561 |
| MTA1 | -545 |
| CANX | -540 |
| TLR1 | -517 |
| VPS4B | -506 |
| CPSF6 | -503 |
| NUS1 | -501 |
| AHCYL1 | -485 |
| RPL6 | -483 |
| RPS16 | -451 |
| CYP11A1 | -443 |
| RPS2 | -411 |
| RPL14 | -367 |
| CTSG | -319 |
| MLH1 | -318 |
| VTA1 | -306 |
| RPL24 | -289 |
| MAN2A1 | -288 |
| CYP2U1 | -276 |
| AMER1 | -249 |
| EP300 | -244 |
| PSMB8 | -235 |
| RBPJ | -194 |
| STAM2 | -192 |
| XRCC5 | -190 |
| EIF2AK3 | -184 |
| SV2A | -169 |
| SLC16A1 | -162 |
| RPL5 | -160 |
| NUP153 | -156 |
| PRKAR2A | -154 |
| DUSP7 | -150 |
| RAP1A | -109 |
| PIK3CB | -106 |
| H2AZ1 | -91 |
| SLC33A1 | -62 |
| POLR2A | -59 |
| PSME4 | -48 |
| CAMK2B | -37 |
| DVL3 | -33 |
| RBBP7 | -26 |
| GNAZ | -7 |
| RPS9 | 11 |
| ZCRB1 | 16 |
| WIPF1 | 21 |
| PSMD6 | 26 |
| PDPK1 | 33 |
| RAD51AP1 | 50 |
| AGGF1 | 54 |
| PTGER2 | 94 |
| AP1G1 | 107 |
| SEL1L | 121 |
| BAG4 | 122 |
| STAT2 | 146 |
| PARP10 | 153 |
| GCLC | 180 |
| NFKBIA | 181 |
| PPP2R5C | 198 |
| H2AC6 | 204 |
| NCBP1 | 218 |
| RPS27L | 222 |
| RPS27A | 229 |
| SLC12A6 | 282 |
| ERCC2 | 315 |
| RPL22 | 345 |
| H2AW | 354 |
| IPO5 | 364 |
| TLR6 | 378 |
| PSMA1 | 379 |
| CHD4 | 383 |
| RPL39 | 390 |
| MYO5A | 391 |
| H2BU1 | 397 |
| TGFBR1 | 415 |
| NCBP2 | 422 |
| VPS37D | 452 |
| MIB1 | 456 |
| SLC9A6 | 464 |
| TICAM1 | 465 |
| BCR | 471 |
| CAMK2A | 491 |
| SLC3A2 | 494 |
| NFKB1 | 503 |
| TBL1X | 506 |
| H2AZ2 | 509 |
| RPS4Y1 | 514 |
| GNG10 | 545 |
| DCN | 553 |
| CDC16 | 578 |
| GTF2F2 | 587 |
| ELOA | 595 |
| MGAT4A | 612 |
| GNE | 621 |
| NCK1 | 629 |
| VHL | 652 |
| GPC1 | 659 |
| CLCN6 | 675 |
| ESR1 | 690 |
| FGF18 | 721 |
| MAP2K4 | 772 |
| ST3GAL4 | 774 |
| EED | 800 |
| RAP1B | 813 |
| ZFYVE9 | 817 |
| CHMP2B | 829 |
| TCEA1 | 835 |
| FZD4 | 867 |
| HSPG2 | 885 |
| PML | 912 |
| GYG2 | 916 |
| ATP6V1H | 924 |
| ALG14 | 928 |
| GALT | 941 |
| RNGTT | 957 |
| ACTR2 | 1000 |
| CASP1 | 1004 |
| RPS13 | 1006 |
| STAT1 | 1015 |
| ATM | 1033 |
| MYO18A | 1081 |
| PTGES3 | 1088 |
| RBBP4 | 1093 |
| MAP3K11 | 1117 |
| GPR27 | 1119 |
| ST3GAL3 | 1150 |
| IDS | 1175 |
| MECP2 | 1176 |
| CHMP3 | 1232 |
| TAF2 | 1240 |
| ERCC3 | 1258 |
| ADRB2 | 1284 |
| PABPN1 | 1356 |
| DNAJC3 | 1382 |
| SFTPD | 1388 |
| ADCY6 | 1400 |
| CUL1 | 1406 |
| HSP90AB1 | 1424 |
| CAMK4 | 1427 |
| PIK3CD | 1455 |
| YWHAB | 1469 |
| PPP2R5E | 1485 |
| S100A9 | 1503 |
| TAF4 | 1507 |
| PRKAR2B | 1526 |
| KPNA4 | 1528 |
| BCL2A1 | 1543 |
| UBE2E1 | 1544 |
| RNF213 | 1560 |
| MAPK1 | 1610 |
| PARP4 | 1613 |
| ALK | 1636 |
| CALM1 | 1638 |
| KPNA1 | 1641 |
| MTRR | 1643 |
| QKI | 1662 |
| F12 | 1679 |
| CDK7 | 1713 |
| RPL7 | 1738 |
| NRAS | 1742 |
| UBE2C | 1747 |
| IKBKB | 1755 |
| CXCR4 | 1758 |
| H2BC21 | 1774 |
| MMADHC | 1787 |
| RB1 | 1797 |
| RCC1 | 1806 |
| APC | 1828 |
| VPS37C | 1841 |
| FNTA | 1848 |
| MAMLD1 | 1899 |
| TAF11 | 1905 |
| DPM1 | 1909 |
| TGFBR2 | 1948 |
| VAV3 | 1970 |
| MSH2 | 1975 |
| ANTXR2 | 1990 |
| CRK | 1993 |
| CBLL1 | 2012 |
| GNAI3 | 2020 |
| NR3C1 | 2034 |
| NMT2 | 2064 |
| EPM2A | 2084 |
| NUP155 | 2114 |
| NUP35 | 2129 |
| MGAT4C | 2130 |
| H2AC18 | 2134 |
| PPP1CB | 2156 |
| NUP54 | 2157 |
| PIK3CA | 2176 |
| TBP | 2238 |
| SMAD4 | 2253 |
| SFPQ | 2260 |
| CSF2RB | 2267 |
| REST | 2271 |
| GTF2E1 | 2297 |
| AKAP9 | 2316 |
| NCKAP1 | 2330 |
| CHMP5 | 2344 |
| ITGA2B | 2353 |
| FKBP1A | 2371 |
| GSDMD | 2372 |
| SLC3A1 | 2390 |
| ATRX | 2395 |
| PARP9 | 2423 |
| KPNB1 | 2425 |
| NUP43 | 2453 |
| ELL | 2462 |
| NOX4 | 2465 |
| CHUK | 2486 |
| PRKX | 2487 |
| LHCGR | 2488 |
| FLT3 | 2506 |
| SUGT1 | 2512 |
| AP3B1 | 2517 |
| GTF2H5 | 2536 |
| PAK2 | 2552 |
| TAF9B | 2561 |
| MAML1 | 2634 |
| SLC26A4 | 2649 |
| DYNC1LI2 | 2656 |
| RPL36A | 2688 |
| E2F2 | 2726 |
| ERBB3 | 2738 |
| B3GLCT | 2794 |
| MSH6 | 2855 |
| PARP8 | 2899 |
| WDR48 | 2906 |
| CHMP4C | 2917 |
| CDK5R1 | 2923 |
| TLR7 | 2925 |
| DNA2 | 2928 |
| WASF3 | 2959 |
| JAK2 | 2971 |
| GNG12 | 2973 |
| C3 | 2977 |
| RAD51 | 2978 |
| BLM | 2987 |
| GTF2H2 | 3000 |
| GPC4 | 3048 |
| GTF2A1 | 3054 |
| IRS1 | 3060 |
| SRPK2 | 3066 |
| GALNT1 | 3072 |
| CCNC | 3078 |
| PMS2 | 3082 |
| IFNAR2 | 3115 |
| SPON1 | 3126 |
| CYSLTR2 | 3130 |
| RANBP2 | 3171 |
| RPSA | 3175 |
| SLC35A1 | 3178 |
| MAML2 | 3183 |
| NELFCD | 3187 |
| DYNC1I2 | 3198 |
| GCC2 | 3221 |
| HHAT | 3223 |
| DUSP6 | 3235 |
| UBC | 3246 |
| ACACA | 3247 |
| ELOC | 3260 |
| SNW1 | 3266 |
| PRKAR1A | 3280 |
| EML4 | 3286 |
| CPSF4 | 3287 |
| GCLM | 3292 |
| TAF4B | 3300 |
| CUL5 | 3316 |
| IFNGR1 | 3321 |
| KAT2A | 3322 |
| ABI2 | 3335 |
| ACTR3 | 3346 |
| CREB1 | 3370 |
| FGFR2 | 3404 |
| CDKN1C | 3418 |
| SPON2 | 3448 |
| MCCC1 | 3451 |
| CBL | 3452 |
| GNG2 | 3460 |
| CEBPB | 3467 |
| PIK3C3 | 3477 |
| CASP8 | 3510 |
| PPP2CA | 3519 |
| KITLG | 3557 |
| RBBP8 | 3559 |
| PDGFA | 3597 |
| MMAA | 3645 |
| TRIM24 | 3656 |
| PSMD12 | 3658 |
| NUP133 | 3662 |
| NEIL1 | 3676 |
| HTR6 | 3681 |
| HSP90AA1 | 3693 |
| TNKS | 3694 |
| ENTPD5 | 3712 |
| FOXO4 | 3729 |
| PTPN11 | 3742 |
| XRCC2 | 3747 |
| LRP5 | 3784 |
| CSNK1A1 | 3789 |
| PSMC6 | 3801 |
| STRN | 3812 |
| FGF17 | 3818 |
| KIF5B | 3823 |
| HGF | 3844 |
| NLRP3 | 3857 |
| ROCK1 | 3867 |
| ADCY2 | 3878 |
| CDC37 | 3884 |
| KRAS | 3903 |
| KPNA3 | 3912 |
| SUZ12 | 3951 |
| SUMO1 | 3974 |
| DNMT3A | 3975 |
| FZD5 | 3978 |
| ADCY5 | 4004 |
| H3-3A | 4015 |
| ITPR2 | 4036 |
| KAT2B | 4056 |
| ABI1 | 4070 |
| TAF5 | 4119 |
| PSMB9 | 4121 |
| CRBN | 4124 |
| ATP1B2 | 4141 |
| RAD51C | 4142 |
| PALB2 | 4160 |
| NBN | 4173 |
| CYSLTR1 | 4184 |
| HMOX1 | 4200 |
| GCK | 4205 |
| EZH2 | 4236 |
| MYH9 | 4253 |
| CD3G | 4272 |
| SHC1 | 4317 |
| TNKS2 | 4320 |
| CHD3 | 4330 |
| SEH1L | 4352 |
| ANAPC1 | 4391 |
| SHOC2 | 4402 |
| PPP1R3C | 4413 |
| TAF3 | 4419 |
| CDC27 | 4464 |
| NUP58 | 4488 |
| VPS37A | 4490 |
| NFKB2 | 4495 |
| TAF9 | 4507 |
| ST6GAL1 | 4514 |
| CEBPD | 4516 |
| ADAM17 | 4517 |
| JAG2 | 4530 |
| LIG1 | 4533 |
| GNB4 | 4535 |
| ITGB1 | 4542 |
| CCNE2 | 4551 |
| ARID4B | 4557 |
| TAF13 | 4565 |
| CUL3 | 4595 |
| CDK8 | 4636 |
| JAK1 | 4640 |
| GGT5 | 4668 |
| RPIA | 4687 |
| LRP6 | 4709 |
| RPL36AL | 4730 |
| RCOR1 | 4732 |
| GATAD2B | 4745 |
| PPM1B | 4840 |
| ST3GAL2 | 4843 |
| RPL9 | 4853 |
| KANK1 | 4867 |
| OMD | 4868 |
| HIP1 | 4883 |
| WASL | 4892 |
| PHF21A | 4935 |
| APH1B | 4938 |
| FGFR1OP2 | 4940 |
| SYT2 | 4944 |
| E2F3 | 5003 |
| SPTBN1 | 5040 |
| PSMA3 | 5077 |
| RPL22L1 | 5078 |
| ADCY3 | 5125 |
| IL1R1 | 5143 |
| STAM | 5156 |
| SLC4A4 | 5158 |
| ETV6 | 5160 |
| PDGFRB | 5161 |
| CCNT2 | 5180 |
| IL10 | 5196 |
| EPS15 | 5214 |
| MTR | 5215 |
| CNKSR1 | 5235 |
| DKK2 | 5238 |
| NUP160 | 5248 |
| ALG13 | 5249 |
| SUDS3 | 5287 |
| HDAC7 | 5297 |
| HMGB1 | 5302 |
| FAM114A2 | 5311 |
| MDM2 | 5371 |
| SEM1 | 5372 |
| GPC2 | 5376 |
| UBE2S | 5380 |
| AVPR2 | 5390 |
| HDAC8 | 5404 |
| CTBP2 | 5416 |
| UBE2D1 | 5427 |
| AKT3 | 5437 |
| SOS1 | 5452 |
| DUT | 5483 |
| RAB5A | 5503 |
| IRAK4 | 5507 |
| TAF1 | 5513 |
| CNTRL | 5519 |
| EXO1 | 5562 |
| MAPK8 | 5565 |
| GSK3B | 5609 |
| NPM1 | 5611 |
| TENT4A | 5662 |
| PSIP1 | 5674 |
| TRAK1 | 5676 |
| ABCC9 | 5681 |
| WNT5A | 5694 |
| CTNND1 | 5728 |
| RAD51D | 5753 |
| CTNNB1 | 5757 |
| NUP50 | 5758 |
| SLC35D1 | 5788 |
| GTF2B | 5818 |
| PLCG1 | 5830 |
| WASF1 | 5834 |
| GALNT3 | 5872 |
| BARD1 | 5883 |
| FIP1L1 | 5892 |
| DOCK1 | 5903 |
| TAF15 | 5909 |
| SMAD2 | 5913 |
| POLA1 | 5924 |
| BIRC6 | 5977 |
| SLC24A1 | 5980 |
| MAML3 | 5984 |
| NRG2 | 5992 |
| RAMP2 | 6003 |
| EIF2AK2 | 6054 |
| NRG4 | 6060 |
| WRN | 6108 |
| MAP2K6 | 6128 |
| HDAC2 | 6141 |
| CDK6 | 6175 |
| MNAT1 | 6219 |
| CAMK2G | 6254 |
| LARGE1 | 6267 |
| DYNC1LI1 | 6270 |
| HEPH | 6310 |
| VPS36 | 6323 |
| ABCD4 | 6343 |
| ROCK2 | 6347 |
| WIPF3 | 6386 |
| FXR1 | 6409 |
| PPFIBP1 | 6438 |
| FBXW7 | 6440 |
| ADRB1 | 6443 |
| MET | 6514 |
| ABCB4 | 6517 |
| TBL1XR1 | 6553 |
| GTF2H1 | 6570 |
| DHH | 6581 |
| FGF7 | 6661 |
| ANTXR1 | 6677 |
| PDCD6IP | 6682 |
| MYO10 | 6688 |
| BRAF | 6708 |
| PARP14 | 6718 |
| GNB5 | 6724 |
| PIK3R3 | 6755 |
| THSD7A | 6817 |
| CYP19A1 | 6880 |
| ANAPC4 | 6889 |
| MRE11 | 6908 |
| SLC40A1 | 6922 |
| YES1 | 6926 |
| MARK3 | 6944 |
| BRCA2 | 6950 |
| FGF16 | 6962 |
| BDNF | 6990 |
| PTEN | 7006 |
| STAT5B | 7050 |
| GNG4 | 7087 |
| PTGDR | 7099 |
| NF1 | 7127 |
| LMO7 | 7131 |
| AGK | 7150 |
| TBK1 | 7169 |
| ERBIN | 7253 |
| ADORA2A | 7261 |
| VCL | 7281 |
| PDGFB | 7347 |
| SNAP25 | 7382 |
| ARID4A | 7386 |
| RICTOR | 7399 |
| FAM131B | 7403 |
| LRRFIP1 | 7451 |
| FUT8 | 7476 |
| AP1S3 | 7562 |
| ZMYM2 | 7596 |
| LMNA | 7628 |
| RAD51B | 7635 |
| LMNB1 | 7662 |
| CYP7B1 | 7672 |
| ZBP1 | 7679 |
| DYNC1I1 | 7687 |
| KSR2 | 7761 |
| IRS2 | 7770 |
| ATP1B3 | 7774 |
| THSD1 | 7840 |
| PRIM2 | 7857 |
| SKP2 | 7870 |
| DNMT3B | 7873 |
| TCF7L2 | 7879 |
| BCL2L11 | 7902 |
| MYC | 7937 |
| AREG | 7970 |
| UVRAG | 8000 |
| ADAMTS12 | 8006 |
| CDK2 | 8007 |
| GPR176 | 8036 |
| TSHR | 8048 |
| CDH1 | 8078 |
| PTK2 | 8088 |
| XPO1 | 8102 |
| DDX5 | 8105 |
| SAP30 | 8116 |
| SRPK1 | 8130 |
| MPRIP | 8146 |
| KIAA1549 | 8154 |
| CNKSR2 | 8157 |
| PPP2R5A | 8203 |
| CHSY1 | 8230 |
| BRIP1 | 8329 |
| VPS37B | 8331 |
| VIP | 8352 |
| SSPOP | 8392 |
| MTA3 | 8415 |
| GPC3 | 8446 |
| ABCG8 | 8453 |
| PPP2R1B | 8460 |
| CCNT1 | 8496 |
| ENTPD1 | 8516 |
| NFE2L2 | 8542 |
| ERBB4 | 8552 |
| PCCA | 8572 |
| SLC6A3 | 8583 |
| HEY1 | 8600 |
| CDKN1B | 8660 |
| CD36 | 8666 |
| CUBN | 8669 |
| NOTCH3 | 8708 |
| SLC35A3 | 8726 |
| IL6R | 8757 |
| KDM7A | 8784 |
| KDR | 8788 |
| FGF23 | 8821 |
| ALG6 | 8828 |
| F10 | 8831 |
| KPNA5 | 8837 |
| ST6GALNAC2 | 8874 |
| GNG11 | 8919 |
| MEFV | 8931 |
| CEP43 | 8940 |
| PLCG2 | 8985 |
| PIM1 | 8989 |
| ST6GALNAC3 | 9031 |
| S1PR1 | 9037 |
| RAMP3 | 9041 |
| CAMK2D | 9106 |
| CCNH | 9117 |
| BCL11A | 9166 |
| KL | 9183 |
| NUP107 | 9235 |
| JUNB | 9236 |
| GNAI1 | 9325 |
| AVPR1A | 9368 |
| IL1B | 9376 |
| ADCY4 | 9424 |
| CALCRL | 9481 |
| ITPR1 | 9487 |
| TPM4 | 9489 |
| DLL1 | 9495 |
| SYT1 | 9515 |
| JUN | 9573 |
| ABCA4 | 9603 |
| VEGFA | 9645 |
| DUSP8 | 9659 |
| NOTCH1 | 9665 |
| MUC3A | 9677 |
| ADAMTS1 | 9694 |
| SLCO2A1 | 9713 |
| VWF | 9736 |
| HEYL | 9758 |
| ADCYAP1R1 | 9763 |
| NR4A1 | 9789 |
| HDAC9 | 9823 |
| CRHR2 | 9825 |
| FMO3 | 9829 |
| CDKN1A | 9840 |
| IL6 | 9872 |
| NRG1 | 9882 |
| GPR20 | 9891 |
| ESR2 | 9948 |
| ADAMTSL1 | 9951 |
| HEY2 | 9959 |
| ADAMTS4 | 9961 |
| HES1 | 9975 |
| PLK2 | 9987 |
| HSPA1A | 9988 |
| JAG1 | 10003 |
| ADM | 10050 |
| SEMA5B | 10059 |
| ADAMTS18 | 10060 |
| THBS1 | 10064 |
| GAB1 | 10075 |
| NEURL1B | 10111 |
| ADAMTS9 | 10114 |
| NOTCH4 | 10129 |
| FZD6 | 10142 |
| DLL4 | 10161 |
Classical antibody-mediated complement activation
| 200 | |
|---|---|
| set | Classical antibody-mediated complement activation |
| setSize | 45 |
| pANOVA | 2.25e-27 |
| s.dist | -0.933 |
| p.adjustANOVA | 5.45e-25 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| IGHV1-2 | -8953 |
| IGHV1-46 | -8910 |
| IGKV2D-28 | -8875 |
| IGHG4 | -8874 |
| IGKV3-11 | -8864 |
| IGKV1D-39 | -8828 |
| IGLV3-21 | -8806 |
| C1QC | -8796 |
| IGLV3-25 | -8773 |
| IGHV3-33 | -8608 |
| IGLV2-14 | -8572 |
| C1QB | -8526 |
| IGLV1-40 | -8088 |
| C1QA | -8083 |
| IGKV3-15 | -7403 |
| IGHV3-11 | -7017 |
| IGKV1-33 | -4702 |
| C1R | -2949 |
| C1S | -1499 |
FCGR activation
| 383 | |
|---|---|
| set | FCGR activation |
| setSize | 52 |
| pANOVA | 5.76e-26 |
| s.dist | -0.844 |
| p.adjustANOVA | 1.19e-23 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| IGHV1-2 | -8953 |
| IGHV1-46 | -8910 |
| IGKV2D-28 | -8875 |
| IGHG4 | -8874 |
| IGKV3-11 | -8864 |
| IGKV1D-39 | -8828 |
| FGR | -8811 |
| IGLV3-21 | -8806 |
| IGLV3-25 | -8773 |
| IGHV3-33 | -8608 |
| IGLV2-14 | -8572 |
| HCK | -8242 |
| SRC | -8148 |
| IGLV1-40 | -8088 |
| FCGR3A | -8055 |
| IGKV3-15 | -7403 |
| IGHV3-11 | -7017 |
| SYK | -6217 |
| FYN | -4854 |
| FCGR2A | -4754 |
| IGKV1-33 | -4702 |
| FCGR1A | -2944 |
| LYN | -2889 |
| CD247 | -834 |
| CD3G | 4272 |
| YES1 | 6926 |
Initial triggering of complement
| 558 | |
|---|---|
| set | Initial triggering of complement |
| setSize | 57 |
| pANOVA | 8.45e-26 |
| s.dist | -0.803 |
| p.adjustANOVA | 1.53e-23 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| IGHV1-2 | -8953 |
| IGHV1-46 | -8910 |
| IGKV2D-28 | -8875 |
| IGHG4 | -8874 |
| IGKV3-11 | -8864 |
| IGKV1D-39 | -8828 |
| IGLV3-21 | -8806 |
| C1QC | -8796 |
| IGLV3-25 | -8773 |
| CFB | -8616 |
| IGHV3-33 | -8608 |
| IGLV2-14 | -8572 |
| C1QB | -8526 |
| C2 | -8124 |
| IGLV1-40 | -8088 |
| C1QA | -8083 |
| IGKV3-15 | -7403 |
| C4A | -7134 |
| IGHV3-11 | -7017 |
| MASP2 | -5892 |
| CFD | -5789 |
| MASP1 | -4746 |
| IGKV1-33 | -4702 |
| C4B | -4099 |
| C1R | -2949 |
| GZMM | -2461 |
| C1S | -1499 |
| COLEC11 | -449 |
| C3 | 2977 |
| FCN3 | 5904 |
| FCN1 | 7955 |
Infectious disease
| 550 | |
|---|---|
| set | Infectious disease |
| setSize | 761 |
| pANOVA | 4.75e-25 |
| s.dist | -0.22 |
| p.adjustANOVA | 7.66e-23 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| COMT | -9062 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| RPS26 | -8966 |
| FZD7 | -8965 |
| IGHV1-2 | -8953 |
| GPBAR1 | -8950 |
| IGHV1-46 | -8910 |
| UBAP1 | -8894 |
| IGKV2D-28 | -8875 |
| IGHG4 | -8874 |
| P2RX4 | -8868 |
| IGKV3-11 | -8864 |
| ST6GALNAC4 | -8835 |
| IGKV1D-39 | -8828 |
| ATP1B1 | -8826 |
| FGR | -8811 |
| IGLV3-21 | -8806 |
| IGLV3-25 | -8773 |
| CYBA | -8747 |
| CD4 | -8741 |
| NUP210 | -8727 |
| PTHLH | -8686 |
| JAK3 | -8657 |
| SEC13 | -8653 |
| IGHV3-33 | -8608 |
| TUBB | -8597 |
| WAS | -8588 |
| IGLV2-14 | -8572 |
| GNB2 | -8571 |
| RHBDF2 | -8567 |
| SIGMAR1 | -8563 |
| PRKACA | -8490 |
| NCOR2 | -8458 |
| RPN2 | -8394 |
| FXYD6 | -8349 |
| PSMD3 | -8328 |
| GPR84 | -8320 |
| CTDP1 | -8295 |
| TGFB1 | -8281 |
| HCK | -8242 |
| CD8B | -8225 |
| GANAB | -8218 |
| NELFB | -8176 |
| AP1B1 | -8173 |
| GSK3A | -8163 |
| PDCD1 | -8157 |
| PSMD8 | -8149 |
| SRC | -8148 |
| IGLV1-40 | -8088 |
| FCGR3A | -8055 |
| RPS4X | -8028 |
| IFNGR2 | -8015 |
| ENO1 | -8009 |
| MBD3 | -8005 |
| FEN1 | -7968 |
| AP2M1 | -7945 |
| DDOST | -7902 |
| PTH1R | -7898 |
| POM121C | -7894 |
| POMC | -7890 |
| POLR2E | -7886 |
| MGAT1 | -7872 |
| BAIAP2 | -7839 |
| AP2S1 | -7829 |
| VAV1 | -7822 |
| DAD1 | -7820 |
| NT5E | -7815 |
| HMGA1 | -7808 |
| KEAP1 | -7807 |
| STX1A | -7794 |
| IMPDH1 | -7786 |
| POLR2J | -7782 |
| TPR | -7773 |
| HBEGF | -7744 |
| ARF1 | -7717 |
| PSMB10 | -7709 |
| MAP2K7 | -7697 |
| EGFR | -7625 |
| PTGIR | -7623 |
| ARPC1B | -7593 |
| PSMB5 | -7576 |
| RPN1 | -7545 |
| MOGS | -7465 |
| POLR2I | -7462 |
| VPS25 | -7443 |
| GNAI2 | -7430 |
| IGKV3-15 | -7403 |
| TAF6 | -7386 |
| DVL1 | -7361 |
| FXYD2 | -7356 |
| PTGER4 | -7331 |
| STT3A | -7290 |
| PSME3 | -7280 |
| PSMB2 | -7268 |
| SV2B | -7256 |
| GNG5 | -7218 |
| EDEM2 | -7195 |
| GRB2 | -7191 |
| NUP62 | -7186 |
| FNTB | -7181 |
| WASF2 | -7177 |
| CHMP2A | -7162 |
| LCK | -7148 |
| PSMD2 | -7104 |
| SH3GL1 | -7094 |
| UBE2I | -7091 |
| TRIM27 | -7087 |
| AP2A1 | -7041 |
| IGHV3-11 | -7017 |
| PYCARD | -7010 |
| AAAS | -7005 |
| AP1S1 | -6952 |
| MGAT4B | -6946 |
| CHMP6 | -6927 |
| CHMP7 | -6920 |
| NCKIPSD | -6918 |
| BRMS1 | -6900 |
| MC1R | -6886 |
| UBA52 | -6880 |
| CD28 | -6879 |
| CHMP1A | -6877 |
| VIPR2 | -6869 |
| CORO1A | -6828 |
| ADORA2B | -6827 |
| GNB1 | -6821 |
| MYO9B | -6808 |
| ARPC4 | -6731 |
| RANGAP1 | -6714 |
| PSMB6 | -6709 |
| APOBEC3G | -6696 |
| DYNLL2 | -6690 |
| CALR | -6689 |
| ISG15 | -6682 |
| MYH2 | -6671 |
| PSMB3 | -6647 |
| MAP2K2 | -6638 |
| SNF8 | -6634 |
| BTK | -6612 |
| ELOB | -6600 |
| AP1M1 | -6596 |
| HDAC3 | -6566 |
| PARP1 | -6552 |
| C3AR1 | -6548 |
| DPEP2 | -6514 |
| PPIA | -6508 |
| BANF1 | -6497 |
| NELFE | -6491 |
| DYNLL1 | -6465 |
| PSMD4 | -6452 |
| VPS4A | -6443 |
| NUP88 | -6417 |
| GGT1 | -6408 |
| HGS | -6399 |
| RPL26L1 | -6364 |
| SUPT4H1 | -6334 |
| PSMF1 | -6332 |
| MAPK3 | -6329 |
| POLR2G | -6267 |
| GNG7 | -6266 |
| POLR2C | -6264 |
| P2RY11 | -6241 |
| POM121 | -6233 |
| H2BC12 | -6223 |
| SYK | -6217 |
| ADCY8 | -6200 |
| UBB | -6193 |
| ST3GAL1 | -6158 |
| BRK1 | -6144 |
| PSMC5 | -6143 |
| AP2A2 | -6118 |
| GPS2 | -6090 |
| PSMA7 | -6082 |
| AP2B1 | -6058 |
| TAF12 | -6023 |
| TXNIP | -5982 |
| PSMB7 | -5953 |
| MYO1C | -5948 |
| VAMP2 | -5893 |
| NCKAP1L | -5878 |
| ELK1 | -5875 |
| PGK1 | -5872 |
| NOS2 | -5871 |
| PSMC4 | -5866 |
| CHMP4B | -5859 |
| RAB7A | -5854 |
| NOXA1 | -5848 |
| TLR2 | -5828 |
| ARPC3 | -5798 |
| RPL39L | -5767 |
| ADCY1 | -5762 |
| MAN1B1 | -5730 |
| PSMC3 | -5726 |
| GIPR | -5724 |
| ELMO2 | -5690 |
| TRIM28 | -5673 |
| HMG20B | -5672 |
| CD163 | -5579 |
| VIPR1 | -5576 |
| DBP | -5561 |
| ADCY9 | -5551 |
| VCP | -5509 |
| ITPR3 | -5506 |
| PSMB1 | -5473 |
| TSG101 | -5436 |
| NUP93 | -5327 |
| PRKCSH | -5301 |
| SH3GL2 | -5270 |
| RPS14 | -5234 |
| VPS28 | -5178 |
| PSMB4 | -5168 |
| NUP37 | -5152 |
| XRCC6 | -5145 |
| GTF2E2 | -5131 |
| DOCK2 | -5130 |
| FURIN | -5098 |
| ACTB | -5073 |
| POLR2L | -5071 |
| DAXX | -5069 |
| PACS1 | -5061 |
| RAMP1 | -5032 |
| CTSL | -4981 |
| SLC25A4 | -4920 |
| GNAS | -4913 |
| RPL27 | -4912 |
| RPL27A | -4896 |
| FYN | -4854 |
| GTF2F1 | -4776 |
| FCGR2A | -4754 |
| ARPC1A | -4752 |
| P2RX7 | -4748 |
| RPL35 | -4745 |
| SKP1 | -4737 |
| NEDD4L | -4722 |
| NUP188 | -4718 |
| IGKV1-33 | -4702 |
| ARPC2 | -4697 |
| MAP2K1 | -4692 |
| GLP2R | -4667 |
| CLTA | -4661 |
| LTF | -4657 |
| PSMD9 | -4655 |
| FAU | -4625 |
| GNB3 | -4560 |
| VAMP1 | -4493 |
| TYK2 | -4442 |
| RBX1 | -4435 |
| FXYD1 | -4365 |
| DYNC1H1 | -4355 |
| NMT1 | -4325 |
| TLR9 | -4319 |
| GTF2H4 | -4181 |
| PSMC2 | -4179 |
| RPL13 | -4148 |
| DVL2 | -4117 |
| RELA | -4097 |
| PSTPIP1 | -4077 |
| RPL8 | -4049 |
| RPS18 | -4032 |
| RPS10 | -4028 |
| RPS29 | -4009 |
| CCNK | -3961 |
| PRKACB | -3946 |
| VPS33B | -3938 |
| POLR2F | -3890 |
| SAP18 | -3880 |
| RPS21 | -3873 |
| RANBP1 | -3860 |
| PSMD10 | -3849 |
| KPNA2 | -3765 |
| RPS5 | -3741 |
| BTRC | -3694 |
| HLA-A | -3688 |
| MAGT1 | -3673 |
| AP1S2 | -3655 |
| NUP214 | -3603 |
| MGAT2 | -3597 |
| RPS11 | -3569 |
| RPL15 | -3543 |
| RPLP1 | -3524 |
| RPL36 | -3523 |
| RPL4 | -3472 |
| SUPT5H | -3462 |
| IL18 | -3383 |
| H2BC5 | -3370 |
| RPL31 | -3359 |
| SSRP1 | -3338 |
| RAC1 | -3331 |
| SCTR | -3288 |
| RPL23 | -3274 |
| POLR2K | -3261 |
| SUPT16H | -3242 |
| PSMA6 | -3225 |
| TAF7 | -3214 |
| RPL10 | -3210 |
| CDC42 | -3206 |
| RPS25 | -3191 |
| RPL7A | -3188 |
| ITGA4 | -3150 |
| RAN | -3114 |
| MGAT5 | -3110 |
| RPL12 | -3105 |
| TXNRD1 | -3072 |
| RPL29 | -3065 |
| RAE1 | -3056 |
| HRH2 | -3037 |
| RPS19 | -3032 |
| PSME1 | -3031 |
| GNGT2 | -3028 |
| NUP98 | -3024 |
| RPL30 | -3017 |
| TXN | -3012 |
| RPL19 | -2986 |
| GTF2A2 | -2979 |
| RPS8 | -2974 |
| FCGR1A | -2944 |
| LYN | -2889 |
| BECN1 | -2887 |
| RPL35A | -2878 |
| RPLP0 | -2877 |
| ELMO1 | -2743 |
| PSMD7 | -2731 |
| RPL18 | -2728 |
| RPL18A | -2719 |
| RPL13A | -2708 |
| EEF2 | -2697 |
| RPL38 | -2691 |
| WIPF2 | -2680 |
| RPS27 | -2657 |
| PSMA5 | -2649 |
| MVB12B | -2605 |
| PSMC1 | -2604 |
| RPS17 | -2555 |
| CYFIP2 | -2546 |
| CLTC | -2500 |
| PARP6 | -2498 |
| RPS23 | -2494 |
| RPS15 | -2484 |
| CCR5 | -2425 |
| RPL34 | -2389 |
| ATP1A1 | -2352 |
| MVB12A | -2344 |
| CBX1 | -2341 |
| RPS3A | -2337 |
| RPL28 | -2326 |
| HTR7 | -2324 |
| TUSC3 | -2306 |
| PARP16 | -2282 |
| CD9 | -2242 |
| RPLP2 | -2239 |
| SH3KBP1 | -2230 |
| NUP85 | -2218 |
| SLC25A6 | -2184 |
| POLR2H | -2169 |
| NCOR1 | -2161 |
| PSMD14 | -2133 |
| RPL32 | -2131 |
| ADCYAP1 | -2101 |
| RPL3L | -2091 |
| RPL23A | -2081 |
| RPS12 | -2076 |
| RPS15A | -2051 |
| LIG4 | -2008 |
| B2M | -1976 |
| TAF10 | -1955 |
| CHMP4A | -1935 |
| RIPK1 | -1922 |
| NDC1 | -1920 |
| BRD4 | -1907 |
| RNMT | -1883 |
| PSMD1 | -1782 |
| RPL10A | -1766 |
| PSMA4 | -1756 |
| RPS20 | -1746 |
| RPL37A | -1736 |
| XRCC4 | -1735 |
| CDK9 | -1701 |
| MAP2K3 | -1696 |
| RPS28 | -1692 |
| POLR2D | -1681 |
| IFNAR1 | -1680 |
| CYFIP1 | -1658 |
| GRSF1 | -1654 |
| RPS3 | -1643 |
| IMPDH2 | -1641 |
| FKBP4 | -1639 |
| KDM1A | -1631 |
| ABL1 | -1625 |
| PSME2 | -1591 |
| RPS7 | -1576 |
| RPL37 | -1517 |
| DUSP16 | -1486 |
| PSMD11 | -1483 |
| PSMD5 | -1433 |
| RPS24 | -1390 |
| HNRNPK | -1387 |
| SAP30L | -1337 |
| PSMA2 | -1286 |
| RPL3 | -1283 |
| RPS6 | -1245 |
| MAPK14 | -1200 |
| GATAD2A | -1107 |
| ATP1A2 | -1079 |
| RPL26 | -1044 |
| ADCY7 | -1010 |
| STX1B | -1007 |
| ARPC5 | -969 |
| ACTG1 | -959 |
| MRC1 | -943 |
| RPL21 | -907 |
| POLR2B | -873 |
| NELFA | -866 |
| RPL11 | -848 |
| VAV2 | -840 |
| CD247 | -834 |
| RPL41 | -812 |
| SLC25A5 | -807 |
| PRKAR1B | -805 |
| PRMT1 | -759 |
| PSMD13 | -754 |
| NUP205 | -738 |
| MAP1LC3B | -706 |
| NUP42 | -641 |
| MTA2 | -616 |
| RPL17 | -614 |
| GTF2H3 | -612 |
| PIK3R4 | -607 |
| HDAC1 | -580 |
| MTA1 | -545 |
| CANX | -540 |
| VPS4B | -506 |
| AHCYL1 | -485 |
| RPL6 | -483 |
| RPS16 | -451 |
| RPS2 | -411 |
| RPL14 | -367 |
| CTSG | -319 |
| VTA1 | -306 |
| RPL24 | -289 |
| MAN2A1 | -288 |
| PSMB8 | -235 |
| STAM2 | -192 |
| XRCC5 | -190 |
| SV2A | -169 |
| RPL5 | -160 |
| NUP153 | -156 |
| PRKAR2A | -154 |
| POLR2A | -59 |
| PSME4 | -48 |
| DVL3 | -33 |
| RBBP7 | -26 |
| GNAZ | -7 |
| RPS9 | 11 |
| ZCRB1 | 16 |
| WIPF1 | 21 |
| PSMD6 | 26 |
| PTGER2 | 94 |
| AP1G1 | 107 |
| STAT2 | 146 |
| PARP10 | 153 |
| H2AC6 | 204 |
| NCBP1 | 218 |
| RPS27L | 222 |
| RPS27A | 229 |
| ERCC2 | 315 |
| RPL22 | 345 |
| H2AW | 354 |
| IPO5 | 364 |
| PSMA1 | 379 |
| CHD4 | 383 |
| RPL39 | 390 |
| MYO5A | 391 |
| H2BU1 | 397 |
| NCBP2 | 422 |
| VPS37D | 452 |
| NFKB1 | 503 |
| TBL1X | 506 |
| RPS4Y1 | 514 |
| GNG10 | 545 |
| GTF2F2 | 587 |
| ELOA | 595 |
| MGAT4A | 612 |
| NCK1 | 629 |
| VHL | 652 |
| MAP2K4 | 772 |
| ST3GAL4 | 774 |
| EED | 800 |
| CHMP2B | 829 |
| TCEA1 | 835 |
| PML | 912 |
| ATP6V1H | 924 |
| RNGTT | 957 |
| ACTR2 | 1000 |
| CASP1 | 1004 |
| RPS13 | 1006 |
| PTGES3 | 1088 |
| RBBP4 | 1093 |
| GPR27 | 1119 |
| ST3GAL3 | 1150 |
| CHMP3 | 1232 |
| TAF2 | 1240 |
| ERCC3 | 1258 |
| ADRB2 | 1284 |
| PABPN1 | 1356 |
| DNAJC3 | 1382 |
| ADCY6 | 1400 |
| HSP90AB1 | 1424 |
| TAF4 | 1507 |
| PRKAR2B | 1526 |
| KPNA4 | 1528 |
| RNF213 | 1560 |
| MAPK1 | 1610 |
| PARP4 | 1613 |
| CALM1 | 1638 |
| KPNA1 | 1641 |
| CDK7 | 1713 |
| RPL7 | 1738 |
| CXCR4 | 1758 |
| H2BC21 | 1774 |
| RB1 | 1797 |
| RCC1 | 1806 |
| VPS37C | 1841 |
| FNTA | 1848 |
| TAF11 | 1905 |
| VAV3 | 1970 |
| ANTXR2 | 1990 |
| CRK | 1993 |
| CBLL1 | 2012 |
| GNAI3 | 2020 |
| NR3C1 | 2034 |
| NMT2 | 2064 |
| NUP155 | 2114 |
| NUP35 | 2129 |
| MGAT4C | 2130 |
| H2AC18 | 2134 |
| NUP54 | 2157 |
| TBP | 2238 |
| SFPQ | 2260 |
| REST | 2271 |
| GTF2E1 | 2297 |
| NCKAP1 | 2330 |
| CHMP5 | 2344 |
| FKBP1A | 2371 |
| GSDMD | 2372 |
| PARP9 | 2423 |
| KPNB1 | 2425 |
| NUP43 | 2453 |
| ELL | 2462 |
| PRKX | 2487 |
| LHCGR | 2488 |
| SUGT1 | 2512 |
| GTF2H5 | 2536 |
| PAK2 | 2552 |
| TAF9B | 2561 |
| DYNC1LI2 | 2656 |
| RPL36A | 2688 |
| PARP8 | 2899 |
| CHMP4C | 2917 |
| TLR7 | 2925 |
| WASF3 | 2959 |
| JAK2 | 2971 |
| GNG12 | 2973 |
| C3 | 2977 |
| GTF2H2 | 3000 |
| GTF2A1 | 3054 |
| IRS1 | 3060 |
| SRPK2 | 3066 |
| GALNT1 | 3072 |
| IFNAR2 | 3115 |
| CYSLTR2 | 3130 |
| RANBP2 | 3171 |
| RPSA | 3175 |
| NELFCD | 3187 |
| DYNC1I2 | 3198 |
| UBC | 3246 |
| ELOC | 3260 |
| PRKAR1A | 3280 |
| CPSF4 | 3287 |
| TAF4B | 3300 |
| CUL5 | 3316 |
| IFNGR1 | 3321 |
| ABI2 | 3335 |
| ACTR3 | 3346 |
| CREB1 | 3370 |
| CBL | 3452 |
| GNG2 | 3460 |
| PIK3C3 | 3477 |
| PSMD12 | 3658 |
| NUP133 | 3662 |
| HTR6 | 3681 |
| HSP90AA1 | 3693 |
| ENTPD5 | 3712 |
| CSNK1A1 | 3789 |
| PSMC6 | 3801 |
| NLRP3 | 3857 |
| ROCK1 | 3867 |
| ADCY2 | 3878 |
| KPNA3 | 3912 |
| SUZ12 | 3951 |
| SUMO1 | 3974 |
| ADCY5 | 4004 |
| ITPR2 | 4036 |
| ABI1 | 4070 |
| TAF5 | 4119 |
| PSMB9 | 4121 |
| CRBN | 4124 |
| ATP1B2 | 4141 |
| CYSLTR1 | 4184 |
| HMOX1 | 4200 |
| EZH2 | 4236 |
| MYH9 | 4253 |
| CD3G | 4272 |
| CHD3 | 4330 |
| SEH1L | 4352 |
| TAF3 | 4419 |
| NUP58 | 4488 |
| VPS37A | 4490 |
| NFKB2 | 4495 |
| TAF9 | 4507 |
| ST6GAL1 | 4514 |
| CEBPD | 4516 |
| ADAM17 | 4517 |
| LIG1 | 4533 |
| GNB4 | 4535 |
| ITGB1 | 4542 |
| ARID4B | 4557 |
| TAF13 | 4565 |
| CUL3 | 4595 |
| JAK1 | 4640 |
| GGT5 | 4668 |
| RPL36AL | 4730 |
| RCOR1 | 4732 |
| GATAD2B | 4745 |
| ST3GAL2 | 4843 |
| RPL9 | 4853 |
| WASL | 4892 |
| PHF21A | 4935 |
| SYT2 | 4944 |
| PSMA3 | 5077 |
| RPL22L1 | 5078 |
| ADCY3 | 5125 |
| IL1R1 | 5143 |
| STAM | 5156 |
| CCNT2 | 5180 |
| IL10 | 5196 |
| EPS15 | 5214 |
| NUP160 | 5248 |
| SUDS3 | 5287 |
| SEM1 | 5372 |
| AVPR2 | 5390 |
| DUT | 5483 |
| RAB5A | 5503 |
| TAF1 | 5513 |
| MAPK8 | 5565 |
| GSK3B | 5609 |
| NPM1 | 5611 |
| PSIP1 | 5674 |
| WNT5A | 5694 |
| CTNND1 | 5728 |
| CTNNB1 | 5757 |
| NUP50 | 5758 |
| GTF2B | 5818 |
| PLCG1 | 5830 |
| WASF1 | 5834 |
| DOCK1 | 5903 |
| TAF15 | 5909 |
| RAMP2 | 6003 |
| EIF2AK2 | 6054 |
| MAP2K6 | 6128 |
| HDAC2 | 6141 |
| MNAT1 | 6219 |
| DYNC1LI1 | 6270 |
| VPS36 | 6323 |
| ROCK2 | 6347 |
| WIPF3 | 6386 |
| ADRB1 | 6443 |
| MET | 6514 |
| TBL1XR1 | 6553 |
| GTF2H1 | 6570 |
| ANTXR1 | 6677 |
| PDCD6IP | 6682 |
| MYO10 | 6688 |
| PARP14 | 6718 |
| GNB5 | 6724 |
| YES1 | 6926 |
| GNG4 | 7087 |
| PTGDR | 7099 |
| TBK1 | 7169 |
| ADORA2A | 7261 |
| SNAP25 | 7382 |
| ARID4A | 7386 |
| FUT8 | 7476 |
| AP1S3 | 7562 |
| ZBP1 | 7679 |
| DYNC1I1 | 7687 |
| ATP1B3 | 7774 |
| UVRAG | 8000 |
| GPR176 | 8036 |
| TSHR | 8048 |
| CDH1 | 8078 |
| PTK2 | 8088 |
| XPO1 | 8102 |
| DDX5 | 8105 |
| SAP30 | 8116 |
| SRPK1 | 8130 |
| VPS37B | 8331 |
| VIP | 8352 |
| MTA3 | 8415 |
| CCNT1 | 8496 |
| ENTPD1 | 8516 |
| NFE2L2 | 8542 |
| IL6R | 8757 |
| KPNA5 | 8837 |
| ST6GALNAC2 | 8874 |
| GNG11 | 8919 |
| MEFV | 8931 |
| PLCG2 | 8985 |
| ST6GALNAC3 | 9031 |
| S1PR1 | 9037 |
| RAMP3 | 9041 |
| CCNH | 9117 |
| NUP107 | 9235 |
| GNAI1 | 9325 |
| IL1B | 9376 |
| ADCY4 | 9424 |
| CALCRL | 9481 |
| ITPR1 | 9487 |
| SYT1 | 9515 |
| JUN | 9573 |
| VEGFA | 9645 |
| ADCYAP1R1 | 9763 |
| CRHR2 | 9825 |
| IL6 | 9872 |
| GPR20 | 9891 |
| PLK2 | 9987 |
| HSPA1A | 9988 |
| ADM | 10050 |
Creation of C4 and C2 activators
| 228 | |
|---|---|
| set | Creation of C4 and C2 activators |
| setSize | 50 |
| pANOVA | 9.05e-25 |
| s.dist | -0.839 |
| p.adjustANOVA | 1.31e-22 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| IGHV1-2 | -8953 |
| IGHV1-46 | -8910 |
| IGKV2D-28 | -8875 |
| IGHG4 | -8874 |
| IGKV3-11 | -8864 |
| IGKV1D-39 | -8828 |
| IGLV3-21 | -8806 |
| C1QC | -8796 |
| IGLV3-25 | -8773 |
| IGHV3-33 | -8608 |
| IGLV2-14 | -8572 |
| C1QB | -8526 |
| IGLV1-40 | -8088 |
| C1QA | -8083 |
| IGKV3-15 | -7403 |
| IGHV3-11 | -7017 |
| MASP2 | -5892 |
| MASP1 | -4746 |
| IGKV1-33 | -4702 |
| C1R | -2949 |
| C1S | -1499 |
| COLEC11 | -449 |
| FCN3 | 5904 |
| FCN1 | 7955 |
CD22 mediated BCR regulation
| 128 | |
|---|---|
| set | CD22 mediated BCR regulation |
| setSize | 43 |
| pANOVA | 1.18e-24 |
| s.dist | -0.902 |
| p.adjustANOVA | 1.55e-22 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGHM | -9118 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGHD | -9085 |
| IGKV2-28 | -9071 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGHM | -9118 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGHD | -9085 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| CD79A | -9036 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| IGHV1-2 | -8953 |
| IGHV1-46 | -8910 |
| IGKV2D-28 | -8875 |
| IGKV3-11 | -8864 |
| IGKV1D-39 | -8828 |
| IGLV3-21 | -8806 |
| IGLV3-25 | -8773 |
| IGHV3-33 | -8608 |
| IGLV2-14 | -8572 |
| PTPN6 | -8357 |
| IGLV1-40 | -8088 |
| IGKV3-15 | -7403 |
| IGHV3-11 | -7017 |
| CD22 | -4929 |
| IGKV1-33 | -4702 |
| LYN | -2889 |
| CD79B | 6744 |
Neutrophil degranulation
| 765 | |
|---|---|
| set | Neutrophil degranulation |
| setSize | 441 |
| pANOVA | 4.05e-24 |
| s.dist | -0.281 |
| p.adjustANOVA | 4.9e-22 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SIRPB1 | -9101 |
| CYB5R3 | -9018 |
| SERPINA1 | -8963 |
| GRN | -8951 |
| GAA | -8936 |
| LAMP1 | -8930 |
| OSCAR | -8923 |
| CKAP4 | -8916 |
| TMBIM1 | -8914 |
| CTSA | -8873 |
| S100A11 | -8865 |
| CD68 | -8853 |
| ALDH3B1 | -8840 |
| NCSTN | -8815 |
| FGR | -8811 |
| ORMDL3 | -8807 |
| CSTB | -8805 |
| SURF4 | -8799 |
| RNASE2 | -8797 |
| CYBA | -8747 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SIRPB1 | -9101 |
| CYB5R3 | -9018 |
| SERPINA1 | -8963 |
| GRN | -8951 |
| GAA | -8936 |
| LAMP1 | -8930 |
| OSCAR | -8923 |
| CKAP4 | -8916 |
| TMBIM1 | -8914 |
| CTSA | -8873 |
| S100A11 | -8865 |
| CD68 | -8853 |
| ALDH3B1 | -8840 |
| NCSTN | -8815 |
| FGR | -8811 |
| ORMDL3 | -8807 |
| CSTB | -8805 |
| SURF4 | -8799 |
| RNASE2 | -8797 |
| CYBA | -8747 |
| HK3 | -8652 |
| ALDOA | -8627 |
| ITGB2 | -8620 |
| ADGRE5 | -8603 |
| TUBB | -8597 |
| SIGLEC14 | -8594 |
| ANPEP | -8527 |
| MAN2B1 | -8524 |
| DOK3 | -8498 |
| CTSB | -8493 |
| LAIR1 | -8472 |
| COMMD9 | -8460 |
| SLC11A1 | -8457 |
| ATP6V0C | -8415 |
| ATG7 | -8380 |
| LILRB2 | -8379 |
| PTPN6 | -8357 |
| TYROBP | -8356 |
| PSMD3 | -8328 |
| GPR84 | -8320 |
| RHOG | -8288 |
| TOLLIP | -8276 |
| GHDC | -8267 |
| FUCA2 | -8249 |
| DPP7 | -8205 |
| GLB1 | -8189 |
| LYZ | -8186 |
| FOLR3 | -8171 |
| APRT | -8130 |
| FCER1G | -8128 |
| ALDOC | -8085 |
| CD55 | -8080 |
| CSNK2B | -8078 |
| SIGLEC5 | -8058 |
| LILRB3 | -8035 |
| CXCL1 | -8034 |
| GALNS | -7969 |
| TRAPPC1 | -7966 |
| PSAP | -7953 |
| KCNAB2 | -7943 |
| CAPN1 | -7920 |
| TXNDC5 | -7914 |
| DDOST | -7902 |
| CTSD | -7893 |
| CANT1 | -7866 |
| FTL | -7828 |
| ITGAM | -7806 |
| DBNL | -7804 |
| IMPDH1 | -7786 |
| ALOX5 | -7785 |
| RNASET2 | -7680 |
| GSTP1 | -7676 |
| TMEM179B | -7675 |
| MVP | -7640 |
| APEH | -7616 |
| CD300A | -7613 |
| CTSZ | -7584 |
| METTL7A | -7577 |
| VAMP8 | -7535 |
| GM2A | -7520 |
| DNASE1L1 | -7509 |
| CD53 | -7506 |
| PKM | -7496 |
| CD63 | -7486 |
| VAT1 | -7456 |
| ARSA | -7432 |
| GUSB | -7411 |
| RAB3D | -7358 |
| LAMTOR1 | -7337 |
| PRG2 | -7266 |
| SLC2A5 | -7149 |
| ANXA2 | -7132 |
| CST3 | -7129 |
| NDUFC2 | -7108 |
| PSMD2 | -7104 |
| PGM1 | -7071 |
| HMOX2 | -7026 |
| ACLY | -7023 |
| PFKL | -7021 |
| SIGLEC9 | -7013 |
| PYCARD | -7010 |
| MIF | -7006 |
| MPO | -6977 |
| CD33 | -6926 |
| PRKCD | -6909 |
| CYSTM1 | -6875 |
| AZU1 | -6868 |
| TCIRG1 | -6863 |
| SNAP29 | -6830 |
| EPX | -6806 |
| PRDX4 | -6797 |
| SIRPA | -6788 |
| ENPP4 | -6759 |
| RHOA | -6754 |
| FUCA1 | -6706 |
| RAB5C | -6693 |
| PYGB | -6678 |
| HSPA8 | -6665 |
| DNAJC5 | -6663 |
| LAMTOR2 | -6641 |
| AP1M1 | -6596 |
| C3AR1 | -6548 |
| PTPRN2 | -6546 |
| NFAM1 | -6523 |
| PPIA | -6508 |
| DYNLL1 | -6465 |
| FTH1 | -6455 |
| RAB5B | -6400 |
| AOC1 | -6397 |
| BRI3 | -6394 |
| PRTN3 | -6386 |
| PSEN1 | -6281 |
| ATP6V0A1 | -6280 |
| PDAP1 | -6258 |
| GPI | -6235 |
| TUBB4B | -6218 |
| IGF2R | -6196 |
| CD14 | -6153 |
| AP2A2 | -6118 |
| P2RX1 | -6092 |
| PA2G4 | -6056 |
| ACTR1B | -6022 |
| PGAM1 | -6006 |
| HVCN1 | -5979 |
| LGALS3 | -5963 |
| PSMB7 | -5953 |
| TIMP2 | -5932 |
| RAB37 | -5902 |
| TRPM2 | -5896 |
| NCKAP1L | -5878 |
| RAB7A | -5854 |
| TLR2 | -5828 |
| CFD | -5789 |
| STBD1 | -5764 |
| RHOF | -5736 |
| PSMC3 | -5726 |
| PTGES2 | -5671 |
| UBR4 | -5637 |
| PDXK | -5585 |
| VCP | -5509 |
| NPC2 | -5501 |
| PSMB1 | -5473 |
| DIAPH1 | -5472 |
| UNC13D | -5470 |
| HEXB | -5455 |
| MLEC | -5382 |
| FAF2 | -5362 |
| CTSS | -5358 |
| SLC15A4 | -5316 |
| ACAA1 | -5304 |
| PRDX6 | -5286 |
| CD44 | -5281 |
| COTL1 | -5238 |
| XRCC6 | -5145 |
| OLR1 | -5138 |
| DOCK2 | -5130 |
| NME2 | -5012 |
| AMPD3 | -4970 |
| CFP | -4887 |
| GLIPR1 | -4882 |
| QSOX1 | -4847 |
| AGPAT2 | -4846 |
| GNS | -4788 |
| CPNE1 | -4785 |
| NEU1 | -4756 |
| FCGR2A | -4754 |
| SERPINB6 | -4751 |
| VPS35L | -4738 |
| DEFA4 | -4707 |
| BPI | -4682 |
| LTF | -4657 |
| TOM1 | -4624 |
| ARL8A | -4561 |
| LTA4H | -4460 |
| HUWE1 | -4455 |
| ATP6V1D | -4357 |
| DYNC1H1 | -4355 |
| PLAUR | -4209 |
| TICAM2 | -4199 |
| PSMC2 | -4179 |
| GSN | -4173 |
| STK11IP | -4103 |
| PKP1 | -4076 |
| DEFA1 | -4036 |
| SERPINB1 | -4033 |
| GYG1 | -3994 |
| CAP1 | -3949 |
| MANBA | -3901 |
| ACP3 | -3897 |
| AGA | -3893 |
| CDA | -3870 |
| CYBB | -3854 |
| OSTF1 | -3768 |
| FGL2 | -3730 |
| BIN2 | -3707 |
| HLA-A | -3688 |
| MAGT1 | -3673 |
| RAP2B | -3635 |
| JUP | -3580 |
| IQGAP2 | -3492 |
| TMC6 | -3356 |
| RAC1 | -3331 |
| ASAH1 | -3322 |
| PPIE | -3321 |
| PLD1 | -3314 |
| LPCAT1 | -3282 |
| CAMP | -3260 |
| IDH1 | -3258 |
| ATP6AP2 | -3183 |
| KCMF1 | -2999 |
| PTPRJ | -2991 |
| RAB44 | -2971 |
| LAMP2 | -2955 |
| SRP14 | -2850 |
| ARSB | -2736 |
| PSMD7 | -2731 |
| CR1 | -2725 |
| EEF2 | -2697 |
| AGL | -2689 |
| PSMA5 | -2649 |
| ITGAX | -2635 |
| MMP9 | -2629 |
| S100A8 | -2515 |
| C5AR1 | -2504 |
| ITGAV | -2473 |
| ADAM8 | -2446 |
| C6orf120 | -2385 |
| HGSNAT | -2328 |
| IST1 | -2289 |
| PTAFR | -2233 |
| PTPRC | -2154 |
| PSMD14 | -2133 |
| B2M | -1976 |
| SYNGR1 | -1890 |
| DGAT1 | -1889 |
| ATAD3B | -1816 |
| HPSE | -1810 |
| CAB39 | -1802 |
| PSMD1 | -1782 |
| DEGS1 | -1772 |
| LAMTOR3 | -1758 |
| ELANE | -1741 |
| CYFIP1 | -1658 |
| IMPDH2 | -1641 |
| EEF1A1 | -1605 |
| GDI2 | -1535 |
| RAB9B | -1509 |
| PSMD11 | -1483 |
| SPTAN1 | -1454 |
| RAB10 | -1385 |
| CTSH | -1301 |
| PSMA2 | -1286 |
| MAPK14 | -1200 |
| CTSC | -1185 |
| ILF2 | -1166 |
| ERP44 | -1134 |
| PGRMC1 | -1094 |
| CREG1 | -1028 |
| IQGAP1 | -1025 |
| ARHGAP9 | -1009 |
| STK10 | -977 |
| ARPC5 | -969 |
| COPB1 | -893 |
| ALAD | -888 |
| LCN2 | -875 |
| HLA-H | -815 |
| ADAM10 | -804 |
| PSMD13 | -754 |
| YPEL5 | -739 |
| B4GALT1 | -661 |
| RAB31 | -572 |
| CPNE3 | -465 |
| ACTR10 | -373 |
| TMEM63A | -321 |
| CTSG | -319 |
| CRACR2A | -287 |
| CDK13 | -219 |
| XRCC5 | -190 |
| CMTM6 | -131 |
| RAP1A | -109 |
| TBC1D10C | -97 |
| CCT2 | -39 |
| PSMD6 | 26 |
| PYGL | 29 |
| ATP8A1 | 145 |
| CD58 | 163 |
| ATP11A | 281 |
| FRMPD3 | 485 |
| DYNLT1 | 501 |
| NFKB1 | 503 |
| NHLRC3 | 550 |
| CPPED1 | 613 |
| CLEC5A | 625 |
| GOLGA7 | 702 |
| MGST1 | 767 |
| RAB4B | 790 |
| RAP1B | 813 |
| RAB18 | 879 |
| DERA | 944 |
| ACTR2 | 1000 |
| COMMD3 | 1045 |
| STING1 | 1130 |
| BST1 | 1165 |
| DNAJC3 | 1382 |
| HSP90AB1 | 1424 |
| PRCP | 1478 |
| S100A9 | 1503 |
| PAFAH1B2 | 1516 |
| CD47 | 1536 |
| MAPK1 | 1610 |
| NRAS | 1742 |
| ITGAL | 1798 |
| ATP11B | 1882 |
| RAB14 | 1901 |
| MME | 1917 |
| RAB24 | 1920 |
| SCAMP1 | 2005 |
| TNFAIP6 | 2017 |
| MMP8 | 2043 |
| RAB6A | 2072 |
| NAPRT | 2077 |
| FPR1 | 2178 |
| ATP8B4 | 2193 |
| TSPAN14 | 2269 |
| GSDMD | 2372 |
| KPNB1 | 2425 |
| DNAJC13 | 2644 |
| TNFRSF1B | 2872 |
| GLA | 2965 |
| C3 | 2977 |
| CCT8 | 3002 |
| TMEM30A | 3034 |
| GMFG | 3137 |
| BST2 | 3310 |
| ANO6 | 3372 |
| CHI3L1 | 3386 |
| VAPA | 3437 |
| NIT2 | 3498 |
| SVIP | 3595 |
| CAT | 3646 |
| PSMD12 | 3658 |
| PTX3 | 3686 |
| HSP90AA1 | 3693 |
| DSN1 | 3697 |
| HEBP2 | 3703 |
| SLC44A2 | 3834 |
| ROCK1 | 3867 |
| PADI2 | 3928 |
| CEACAM3 | 3957 |
| NFASC | 3959 |
| CAND1 | 4089 |
| PLAU | 4122 |
| NBEAL2 | 4305 |
| PPBP | 4468 |
| MOSPD2 | 4491 |
| HLA-B | 4836 |
| MCEMP1 | 4906 |
| SLPI | 4921 |
| SERPINA3 | 4964 |
| QPCT | 5017 |
| RAP2C | 5100 |
| HP | 5104 |
| SNAP23 | 5187 |
| PLAC8 | 5241 |
| HMGB1 | 5302 |
| ARMC8 | 5310 |
| RAB27A | 5323 |
| OLFM4 | 5408 |
| RAB3A | 5550 |
| CNN2 | 5684 |
| PGM2 | 5693 |
| CEP290 | 5713 |
| HBB | 5795 |
| PGLYRP1 | 5847 |
| IRAG2 | 5941 |
| SELL | 5962 |
| CD59 | 6004 |
| PNP | 6038 |
| CHIT1 | 6264 |
| PLEKHO2 | 6266 |
| DYNC1LI1 | 6270 |
| CEACAM1 | 6329 |
| GGH | 6348 |
| VNN1 | 6989 |
| VCL | 7281 |
| SNAP25 | 7382 |
| GCA | 7447 |
| FRK | 7510 |
| SDCBP | 7519 |
| CLEC12A | 7549 |
| FPR2 | 7694 |
| HLA-C | 7759 |
| FCN1 | 7955 |
| DDX3X | 8042 |
| ADGRE3 | 8356 |
| CD36 | 8666 |
| MNDA | 8733 |
| S100A12 | 8800 |
| HSPA6 | 8872 |
| HSPA1B | 8917 |
| FCAR | 8968 |
| LRG1 | 9040 |
| A1BG | 9149 |
| STOM | 9231 |
| FABP5 | 9265 |
| S100P | 9326 |
| APAF1 | 9365 |
| LRRC7 | 9375 |
| PECAM1 | 9560 |
| CRISPLD2 | 9598 |
| CD93 | 9927 |
| MGAM | 9981 |
| HSPA1A | 9988 |
| MMP25 | 10087 |
| DSP | 10097 |
| PTPRB | 10103 |
| CXCR2 | 10117 |
| ADGRG3 | 10123 |
| CXCR1 | 10135 |
| FCGR3B | 10145 |
| SLC2A3 | 10153 |
Regulation of Complement cascade
| 1008 | |
|---|---|
| set | Regulation of Complement cascade |
| setSize | 74 |
| pANOVA | 1.25e-23 |
| s.dist | -0.673 |
| p.adjustANOVA | 1.4e-21 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| IGHV1-2 | -8953 |
| IGHV1-46 | -8910 |
| IGKV2D-28 | -8875 |
| IGHG4 | -8874 |
| IGKV3-11 | -8864 |
| CD81 | -8856 |
| IGKV1D-39 | -8828 |
| IGLV3-21 | -8806 |
| C1QC | -8796 |
| IGLV3-25 | -8773 |
| CFB | -8616 |
| IGHV3-33 | -8608 |
| IGLV2-14 | -8572 |
| C1QB | -8526 |
| CLU | -8383 |
| C2 | -8124 |
| IGLV1-40 | -8088 |
| C1QA | -8083 |
| CD55 | -8080 |
| IGKV3-15 | -7403 |
| C4A | -7134 |
| IGHV3-11 | -7017 |
| CR2 | -6990 |
| C3AR1 | -6548 |
| C7 | -6464 |
| SERPING1 | -5070 |
| C5AR2 | -4710 |
| IGKV1-33 | -4702 |
| C4B | -4099 |
| CD19 | -3284 |
| C1R | -2949 |
| CR1 | -2725 |
| C5AR1 | -2504 |
| ELANE | -1741 |
| C1S | -1499 |
| CFI | -1444 |
| CFH | -1103 |
| PROS1 | -863 |
| C5 | 536 |
| C4BPB | 614 |
| VTN | 2494 |
| C3 | 2977 |
| C6 | 3124 |
| CFHR3 | 3314 |
| CFHR1 | 4275 |
| CD46 | 4669 |
| CD59 | 6004 |
| CPN2 | 8591 |
Translation
| 1355 | |
|---|---|
| set | Translation |
| setSize | 294 |
| pANOVA | 6.15e-23 |
| s.dist | -0.334 |
| p.adjustANOVA | 6.37e-21 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS26 | -8966 |
| MRPS6 | -8791 |
| MRPL38 | -8772 |
| MRPS34 | -8726 |
| ERAL1 | -8635 |
| MRPS24 | -8489 |
| MRPL57 | -8452 |
| MRPL41 | -8451 |
| MRPL4 | -8434 |
| MRPL12 | -8422 |
| RPN2 | -8394 |
| AURKAIP1 | -8335 |
| TSFM | -8273 |
| MRPL10 | -8223 |
| WARS1 | -8152 |
| MRPL34 | -8071 |
| MRPL43 | -8060 |
| SEC61A1 | -8056 |
| MRPL2 | -8039 |
| RPS4X | -8028 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS26 | -8966 |
| MRPS6 | -8791 |
| MRPL38 | -8772 |
| MRPS34 | -8726 |
| ERAL1 | -8635 |
| MRPS24 | -8489 |
| MRPL57 | -8452 |
| MRPL41 | -8451 |
| MRPL4 | -8434 |
| MRPL12 | -8422 |
| RPN2 | -8394 |
| AURKAIP1 | -8335 |
| TSFM | -8273 |
| MRPL10 | -8223 |
| WARS1 | -8152 |
| MRPL34 | -8071 |
| MRPL43 | -8060 |
| SEC61A1 | -8056 |
| MRPL2 | -8039 |
| RPS4X | -8028 |
| VARS1 | -8026 |
| EIF4G1 | -8010 |
| MRPL16 | -7965 |
| SSR4 | -7948 |
| SRPRB | -7913 |
| DDOST | -7902 |
| MRPS16 | -7777 |
| SPCS1 | -7772 |
| SRPRA | -7771 |
| PARS2 | -7627 |
| APEH | -7616 |
| GSPT2 | -7587 |
| RPN1 | -7545 |
| MRPL20 | -7416 |
| MRPL23 | -7387 |
| EIF3B | -7368 |
| MRPS18A | -7353 |
| VARS2 | -7239 |
| TRMT112 | -7235 |
| MRPS7 | -7107 |
| SEC61B | -7068 |
| MRPS11 | -7057 |
| FARSA | -7055 |
| MRPS18B | -7020 |
| MRPL14 | -6937 |
| MRPS12 | -6931 |
| UBA52 | -6880 |
| MRPL49 | -6736 |
| SRP68 | -6724 |
| MRPL40 | -6680 |
| MRPL54 | -6656 |
| MRPL22 | -6642 |
| SEC11C | -6561 |
| CHCHD1 | -6474 |
| RPL26L1 | -6364 |
| MRPS2 | -6344 |
| SEC61G | -6251 |
| MRPL55 | -6245 |
| MRPL53 | -6232 |
| QARS1 | -6159 |
| AIMP2 | -6102 |
| TUFM | -6084 |
| EEF1A2 | -6060 |
| MRPL24 | -6045 |
| MRPL17 | -6025 |
| GADD45GIP1 | -6013 |
| MRPL9 | -5907 |
| EIF2B2 | -5888 |
| RPL39L | -5767 |
| EIF4EBP1 | -5758 |
| MRPL27 | -5620 |
| MARS1 | -5603 |
| MRPS23 | -5587 |
| MRPS17 | -5568 |
| MRPL46 | -5557 |
| EIF2B1 | -5515 |
| MRPL37 | -5406 |
| MARS2 | -5291 |
| MRPL28 | -5240 |
| RPS14 | -5234 |
| MRPL3 | -5226 |
| EARS2 | -5192 |
| AARS1 | -5139 |
| EEF1A1P5 | -5078 |
| RPL27 | -4912 |
| RPL27A | -4896 |
| EIF4H | -4855 |
| EIF2B5 | -4853 |
| MRPL36 | -4842 |
| MRPS22 | -4795 |
| MRPL13 | -4750 |
| RPL35 | -4745 |
| EIF3F | -4664 |
| FAU | -4625 |
| SSR3 | -4573 |
| TARS2 | -4572 |
| MRPS27 | -4548 |
| MRPL15 | -4532 |
| MRPS21 | -4522 |
| MRPS10 | -4427 |
| MRPL47 | -4298 |
| EPRS1 | -4204 |
| MRPL44 | -4200 |
| EEF1B2 | -4177 |
| RPL13 | -4148 |
| MRPS18C | -4105 |
| RPL8 | -4049 |
| RPS18 | -4032 |
| RPS10 | -4028 |
| RPS29 | -4009 |
| SEC11A | -3992 |
| MRPS26 | -3891 |
| RPS21 | -3873 |
| EIF3K | -3868 |
| SPCS2 | -3859 |
| KARS1 | -3801 |
| MRPL58 | -3776 |
| RPS5 | -3741 |
| MRPS15 | -3732 |
| SSR2 | -3693 |
| MRPL52 | -3676 |
| N6AMT1 | -3612 |
| MRPS14 | -3575 |
| RPS11 | -3569 |
| RPL15 | -3543 |
| RPLP1 | -3524 |
| RPL36 | -3523 |
| EIF3I | -3488 |
| YARS1 | -3481 |
| RPL4 | -3472 |
| MRPL11 | -3457 |
| SARS2 | -3423 |
| MRPL33 | -3419 |
| RPL31 | -3359 |
| MTIF2 | -3276 |
| RPL23 | -3274 |
| MRPL51 | -3240 |
| GARS1 | -3213 |
| RPL10 | -3210 |
| RPS25 | -3191 |
| RPL7A | -3188 |
| SARS1 | -3156 |
| EEF1G | -3124 |
| RPL12 | -3105 |
| SSR1 | -3101 |
| RPL29 | -3065 |
| RPS19 | -3032 |
| RPL30 | -3017 |
| RPL19 | -2986 |
| RPS8 | -2974 |
| CARS1 | -2934 |
| MRPS5 | -2925 |
| RPL35A | -2878 |
| RPLP0 | -2877 |
| SRP14 | -2850 |
| MRPS33 | -2760 |
| HARS2 | -2740 |
| RPL18 | -2728 |
| RPL18A | -2719 |
| RPL13A | -2708 |
| EIF2B4 | -2700 |
| EEF2 | -2697 |
| RPL38 | -2691 |
| RPS27 | -2657 |
| MRPL45 | -2620 |
| MRPL18 | -2588 |
| RPS17 | -2555 |
| EIF5 | -2509 |
| RPS23 | -2494 |
| RPS15 | -2484 |
| HARS1 | -2472 |
| OXA1L | -2469 |
| MRPS9 | -2449 |
| RARS1 | -2420 |
| EIF3D | -2390 |
| RPL34 | -2389 |
| EIF3G | -2353 |
| RPS3A | -2337 |
| RPL28 | -2326 |
| YARS2 | -2245 |
| RPLP2 | -2239 |
| RPL32 | -2131 |
| RPL3L | -2091 |
| RPL23A | -2081 |
| RPS12 | -2076 |
| CARS2 | -2072 |
| RPS15A | -2051 |
| TRAM1 | -2020 |
| MRPL48 | -1949 |
| RPL10A | -1766 |
| MRPL35 | -1757 |
| RPS20 | -1746 |
| RPL37A | -1736 |
| RPS28 | -1692 |
| RPS3 | -1643 |
| EEF1A1 | -1605 |
| RPS7 | -1576 |
| EIF3C | -1564 |
| EEF1D | -1531 |
| RPL37 | -1517 |
| MRPL21 | -1490 |
| FARS2 | -1472 |
| RPS24 | -1390 |
| MRPL30 | -1292 |
| RPL3 | -1283 |
| DAP3 | -1255 |
| RPS6 | -1245 |
| RPL26 | -1044 |
| RPL21 | -907 |
| FARSB | -849 |
| RPL11 | -848 |
| MRPS36 | -836 |
| EIF5B | -830 |
| RPL41 | -812 |
| SRP72 | -795 |
| EEF1E1 | -752 |
| EIF3L | -699 |
| RPL17 | -614 |
| RPL6 | -483 |
| RPS16 | -451 |
| RPS2 | -411 |
| RPL14 | -367 |
| WARS2 | -359 |
| MRPS35 | -312 |
| RPL24 | -289 |
| DARS2 | -273 |
| MRPL50 | -182 |
| RPL5 | -160 |
| RPS9 | 11 |
| SRP54 | 106 |
| MRPS30 | 125 |
| RPS27L | 222 |
| RPS27A | 229 |
| RPL22 | 345 |
| RPL39 | 390 |
| IARS2 | 392 |
| RPS4Y1 | 514 |
| EIF2S1 | 771 |
| MRPL19 | 782 |
| RPS13 | 1006 |
| GSPT1 | 1018 |
| MTFMT | 1111 |
| MRPL1 | 1222 |
| LARS2 | 1293 |
| IARS1 | 1339 |
| EIF4A1 | 1415 |
| EIF1AX | 1508 |
| GFM2 | 1532 |
| MRPL32 | 1711 |
| RPL7 | 1738 |
| ETF1 | 1743 |
| NARS1 | 1852 |
| EIF3J | 1946 |
| AARS2 | 1953 |
| EIF4B | 2088 |
| RARS2 | 2099 |
| TARS1 | 2126 |
| SRP19 | 2150 |
| AIMP1 | 2228 |
| PPA2 | 2296 |
| SRP9 | 2333 |
| EIF4E | 2379 |
| MT-RNR1 | 2469 |
| MRPS25 | 2586 |
| PPA1 | 2589 |
| RPL36A | 2688 |
| MRPS28 | 2930 |
| EIF2S2 | 3109 |
| RPSA | 3175 |
| EIF3E | 3234 |
| EIF3H | 3301 |
| GFM1 | 3529 |
| EIF2S3 | 3667 |
| PTCD3 | 3730 |
| SPCS3 | 3905 |
| EIF3M | 4326 |
| MRPL39 | 4422 |
| MRPS31 | 4480 |
| PABPC1 | 4660 |
| RPL36AL | 4730 |
| DARS1 | 4742 |
| RPL9 | 4853 |
| RPL22L1 | 5078 |
| EIF3A | 5298 |
| SEC61A2 | 5305 |
| MRRF | 5368 |
| NARS2 | 5656 |
| MTIF3 | 5760 |
| LARS1 | 6001 |
| EIF2B3 | 6253 |
| MRPL42 | 6674 |
| EIF4A2 | 6916 |
| MTRF1L | 7847 |
| MT-RNR2 | 8527 |
Complement cascade
| 212 | |
|---|---|
| set | Complement cascade |
| setSize | 81 |
| pANOVA | 1.71e-22 |
| s.dist | -0.627 |
| p.adjustANOVA | 1.66e-20 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| IGHV1-2 | -8953 |
| IGHV1-46 | -8910 |
| IGKV2D-28 | -8875 |
| IGHG4 | -8874 |
| IGKV3-11 | -8864 |
| CD81 | -8856 |
| IGKV1D-39 | -8828 |
| IGLV3-21 | -8806 |
| C1QC | -8796 |
| IGLV3-25 | -8773 |
| CFB | -8616 |
| IGHV3-33 | -8608 |
| IGLV2-14 | -8572 |
| C1QB | -8526 |
| CLU | -8383 |
| C2 | -8124 |
| IGLV1-40 | -8088 |
| C1QA | -8083 |
| CD55 | -8080 |
| IGKV3-15 | -7403 |
| C4A | -7134 |
| IGHV3-11 | -7017 |
| CR2 | -6990 |
| C3AR1 | -6548 |
| C7 | -6464 |
| MASP2 | -5892 |
| CFD | -5789 |
| SERPING1 | -5070 |
| MASP1 | -4746 |
| C5AR2 | -4710 |
| IGKV1-33 | -4702 |
| C4B | -4099 |
| CD19 | -3284 |
| C1R | -2949 |
| CR1 | -2725 |
| C5AR1 | -2504 |
| GZMM | -2461 |
| ELANE | -1741 |
| C1S | -1499 |
| CFI | -1444 |
| CFH | -1103 |
| PROS1 | -863 |
| COLEC11 | -449 |
| C5 | 536 |
| C4BPB | 614 |
| VTN | 2494 |
| C3 | 2977 |
| C6 | 3124 |
| CFHR3 | 3314 |
| CFHR1 | 4275 |
| CD46 | 4669 |
| FCN3 | 5904 |
| CD59 | 6004 |
| FCN1 | 7955 |
| CPN2 | 8591 |
Role of LAT2/NTAL/LAB on calcium mobilization
| 1077 | |
|---|---|
| set | Role of LAT2/NTAL/LAB on calcium mobilization |
| setSize | 49 |
| pANOVA | 3.31e-22 |
| s.dist | -0.799 |
| p.adjustANOVA | 3e-20 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| IGHV1-2 | -8953 |
| IGHV1-46 | -8910 |
| IGKV2D-28 | -8875 |
| IGKV3-11 | -8864 |
| IGKV1D-39 | -8828 |
| IGLV3-21 | -8806 |
| IGLV3-25 | -8773 |
| PIK3R2 | -8767 |
| IGHV3-33 | -8608 |
| IGLV2-14 | -8572 |
| IGLV1-40 | -8088 |
| IGKV3-15 | -7403 |
| GRB2 | -7191 |
| IGHV3-11 | -7017 |
| LAT2 | -6615 |
| PIK3R1 | -6564 |
| SYK | -6217 |
| GAB2 | -5845 |
| FYN | -4854 |
| IGKV1-33 | -4702 |
| LYN | -2889 |
| PIK3CB | -106 |
| PDPK1 | 33 |
| PIK3CA | 2176 |
| SHC1 | 4317 |
| SOS1 | 5452 |
Scavenging of heme from plasma
| 1120 | |
|---|---|
| set | Scavenging of heme from plasma |
| setSize | 46 |
| pANOVA | 6.14e-22 |
| s.dist | -0.82 |
| p.adjustANOVA | 5.24e-20 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHA2 | -9147 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHA2 | -9147 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| JCHAIN | -9063 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| IGHA1 | -9037 |
| LRP1 | -9029 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| IGHV1-2 | -8953 |
| IGHV1-46 | -8910 |
| IGKV2D-28 | -8875 |
| IGKV3-11 | -8864 |
| IGKV1D-39 | -8828 |
| IGLV3-21 | -8806 |
| IGLV3-25 | -8773 |
| IGHV3-33 | -8608 |
| IGLV2-14 | -8572 |
| IGLV1-40 | -8088 |
| IGKV3-15 | -7403 |
| IGHV3-11 | -7017 |
| CD163 | -5579 |
| IGKV1-33 | -4702 |
| APOL1 | -2619 |
| HPX | 3345 |
| HP | 5104 |
| HBA1 | 5744 |
| HBB | 5795 |
FCGR3A-mediated phagocytosis
| 385 | |
|---|---|
| set | FCGR3A-mediated phagocytosis |
| setSize | 99 |
| pANOVA | 2.73e-21 |
| s.dist | -0.55 |
| p.adjustANOVA | 1.98e-19 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| IGHV1-2 | -8953 |
| IGHV1-46 | -8910 |
| IGKV2D-28 | -8875 |
| IGHG4 | -8874 |
| IGKV3-11 | -8864 |
| IGKV1D-39 | -8828 |
| FGR | -8811 |
| IGLV3-21 | -8806 |
| IGLV3-25 | -8773 |
| IGHV3-33 | -8608 |
| WAS | -8588 |
| IGLV2-14 | -8572 |
| HCK | -8242 |
| SRC | -8148 |
| IGLV1-40 | -8088 |
| FCGR3A | -8055 |
| BAIAP2 | -7839 |
| VAV1 | -7822 |
| ARPC1B | -7593 |
| IGKV3-15 | -7403 |
| GRB2 | -7191 |
| WASF2 | -7177 |
| IGHV3-11 | -7017 |
| NCKIPSD | -6918 |
| MYO9B | -6808 |
| ARPC4 | -6731 |
| MYH2 | -6671 |
| BTK | -6612 |
| MAPK3 | -6329 |
| SYK | -6217 |
| BRK1 | -6144 |
| MYO1C | -5948 |
| NCKAP1L | -5878 |
| ARPC3 | -5798 |
| ELMO2 | -5690 |
| ACTB | -5073 |
| FYN | -4854 |
| ARPC1A | -4752 |
| IGKV1-33 | -4702 |
| ARPC2 | -4697 |
| RAC1 | -3331 |
| CDC42 | -3206 |
| LYN | -2889 |
| ELMO1 | -2743 |
| WIPF2 | -2680 |
| CYFIP2 | -2546 |
| CYFIP1 | -1658 |
| ABL1 | -1625 |
| ARPC5 | -969 |
| ACTG1 | -959 |
| VAV2 | -840 |
| CD247 | -834 |
| WIPF1 | 21 |
| MYO5A | 391 |
| NCK1 | 629 |
| ACTR2 | 1000 |
| MAPK1 | 1610 |
| VAV3 | 1970 |
| CRK | 1993 |
| NCKAP1 | 2330 |
| WASF3 | 2959 |
| ABI2 | 3335 |
| ACTR3 | 3346 |
| ABI1 | 4070 |
| MYH9 | 4253 |
| CD3G | 4272 |
| WASL | 4892 |
| WASF1 | 5834 |
| DOCK1 | 5903 |
| WIPF3 | 6386 |
| MYO10 | 6688 |
| YES1 | 6926 |
| PTK2 | 8088 |
Leishmania phagocytosis
| 627 | |
|---|---|
| set | Leishmania phagocytosis |
| setSize | 99 |
| pANOVA | 2.73e-21 |
| s.dist | -0.55 |
| p.adjustANOVA | 1.98e-19 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| IGHV1-2 | -8953 |
| IGHV1-46 | -8910 |
| IGKV2D-28 | -8875 |
| IGHG4 | -8874 |
| IGKV3-11 | -8864 |
| IGKV1D-39 | -8828 |
| FGR | -8811 |
| IGLV3-21 | -8806 |
| IGLV3-25 | -8773 |
| IGHV3-33 | -8608 |
| WAS | -8588 |
| IGLV2-14 | -8572 |
| HCK | -8242 |
| SRC | -8148 |
| IGLV1-40 | -8088 |
| FCGR3A | -8055 |
| BAIAP2 | -7839 |
| VAV1 | -7822 |
| ARPC1B | -7593 |
| IGKV3-15 | -7403 |
| GRB2 | -7191 |
| WASF2 | -7177 |
| IGHV3-11 | -7017 |
| NCKIPSD | -6918 |
| MYO9B | -6808 |
| ARPC4 | -6731 |
| MYH2 | -6671 |
| BTK | -6612 |
| MAPK3 | -6329 |
| SYK | -6217 |
| BRK1 | -6144 |
| MYO1C | -5948 |
| NCKAP1L | -5878 |
| ARPC3 | -5798 |
| ELMO2 | -5690 |
| ACTB | -5073 |
| FYN | -4854 |
| ARPC1A | -4752 |
| IGKV1-33 | -4702 |
| ARPC2 | -4697 |
| RAC1 | -3331 |
| CDC42 | -3206 |
| LYN | -2889 |
| ELMO1 | -2743 |
| WIPF2 | -2680 |
| CYFIP2 | -2546 |
| CYFIP1 | -1658 |
| ABL1 | -1625 |
| ARPC5 | -969 |
| ACTG1 | -959 |
| VAV2 | -840 |
| CD247 | -834 |
| WIPF1 | 21 |
| MYO5A | 391 |
| NCK1 | 629 |
| ACTR2 | 1000 |
| MAPK1 | 1610 |
| VAV3 | 1970 |
| CRK | 1993 |
| NCKAP1 | 2330 |
| WASF3 | 2959 |
| ABI2 | 3335 |
| ACTR3 | 3346 |
| ABI1 | 4070 |
| MYH9 | 4253 |
| CD3G | 4272 |
| WASL | 4892 |
| WASF1 | 5834 |
| DOCK1 | 5903 |
| WIPF3 | 6386 |
| MYO10 | 6688 |
| YES1 | 6926 |
| PTK2 | 8088 |
Parasite infection
| 836 | |
|---|---|
| set | Parasite infection |
| setSize | 99 |
| pANOVA | 2.73e-21 |
| s.dist | -0.55 |
| p.adjustANOVA | 1.98e-19 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| IGHV1-2 | -8953 |
| IGHV1-46 | -8910 |
| IGKV2D-28 | -8875 |
| IGHG4 | -8874 |
| IGKV3-11 | -8864 |
| IGKV1D-39 | -8828 |
| FGR | -8811 |
| IGLV3-21 | -8806 |
| IGLV3-25 | -8773 |
| IGHV3-33 | -8608 |
| WAS | -8588 |
| IGLV2-14 | -8572 |
| HCK | -8242 |
| SRC | -8148 |
| IGLV1-40 | -8088 |
| FCGR3A | -8055 |
| BAIAP2 | -7839 |
| VAV1 | -7822 |
| ARPC1B | -7593 |
| IGKV3-15 | -7403 |
| GRB2 | -7191 |
| WASF2 | -7177 |
| IGHV3-11 | -7017 |
| NCKIPSD | -6918 |
| MYO9B | -6808 |
| ARPC4 | -6731 |
| MYH2 | -6671 |
| BTK | -6612 |
| MAPK3 | -6329 |
| SYK | -6217 |
| BRK1 | -6144 |
| MYO1C | -5948 |
| NCKAP1L | -5878 |
| ARPC3 | -5798 |
| ELMO2 | -5690 |
| ACTB | -5073 |
| FYN | -4854 |
| ARPC1A | -4752 |
| IGKV1-33 | -4702 |
| ARPC2 | -4697 |
| RAC1 | -3331 |
| CDC42 | -3206 |
| LYN | -2889 |
| ELMO1 | -2743 |
| WIPF2 | -2680 |
| CYFIP2 | -2546 |
| CYFIP1 | -1658 |
| ABL1 | -1625 |
| ARPC5 | -969 |
| ACTG1 | -959 |
| VAV2 | -840 |
| CD247 | -834 |
| WIPF1 | 21 |
| MYO5A | 391 |
| NCK1 | 629 |
| ACTR2 | 1000 |
| MAPK1 | 1610 |
| VAV3 | 1970 |
| CRK | 1993 |
| NCKAP1 | 2330 |
| WASF3 | 2959 |
| ABI2 | 3335 |
| ACTR3 | 3346 |
| ABI1 | 4070 |
| MYH9 | 4253 |
| CD3G | 4272 |
| WASL | 4892 |
| WASF1 | 5834 |
| DOCK1 | 5903 |
| WIPF3 | 6386 |
| MYO10 | 6688 |
| YES1 | 6926 |
| PTK2 | 8088 |
Regulation of actin dynamics for phagocytic cup formation
| 1036 | |
|---|---|
| set | Regulation of actin dynamics for phagocytic cup formation |
| setSize | 101 |
| pANOVA | 6.07e-21 |
| s.dist | -0.54 |
| p.adjustANOVA | 4.19e-19 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| IGHV1-2 | -8953 |
| IGHV1-46 | -8910 |
| IGKV2D-28 | -8875 |
| IGHG4 | -8874 |
| IGKV3-11 | -8864 |
| IGKV1D-39 | -8828 |
| IGLV3-21 | -8806 |
| IGLV3-25 | -8773 |
| IGHV3-33 | -8608 |
| WAS | -8588 |
| IGLV2-14 | -8572 |
| IGLV1-40 | -8088 |
| FCGR3A | -8055 |
| LIMK1 | -7870 |
| BAIAP2 | -7839 |
| VAV1 | -7822 |
| ARPC1B | -7593 |
| IGKV3-15 | -7403 |
| GRB2 | -7191 |
| WASF2 | -7177 |
| CFL1 | -7166 |
| IGHV3-11 | -7017 |
| NCKIPSD | -6918 |
| MYO9B | -6808 |
| ARPC4 | -6731 |
| MYH2 | -6671 |
| BTK | -6612 |
| MAPK3 | -6329 |
| SYK | -6217 |
| BRK1 | -6144 |
| MYO1C | -5948 |
| NCKAP1L | -5878 |
| ARPC3 | -5798 |
| ELMO2 | -5690 |
| ACTB | -5073 |
| FCGR2A | -4754 |
| ARPC1A | -4752 |
| IGKV1-33 | -4702 |
| ARPC2 | -4697 |
| NF2 | -4649 |
| RAC1 | -3331 |
| PAK1 | -3309 |
| CDC42 | -3206 |
| FCGR1A | -2944 |
| ELMO1 | -2743 |
| WIPF2 | -2680 |
| CYFIP2 | -2546 |
| CYFIP1 | -1658 |
| ABL1 | -1625 |
| ARPC5 | -969 |
| ACTG1 | -959 |
| VAV2 | -840 |
| CD247 | -834 |
| WIPF1 | 21 |
| MYO5A | 391 |
| NCK1 | 629 |
| ACTR2 | 1000 |
| HSP90AB1 | 1424 |
| MAPK1 | 1610 |
| VAV3 | 1970 |
| CRK | 1993 |
| NCKAP1 | 2330 |
| WASF3 | 2959 |
| ABI2 | 3335 |
| ACTR3 | 3346 |
| HSP90AA1 | 3693 |
| ABI1 | 4070 |
| MYH9 | 4253 |
| CD3G | 4272 |
| WASL | 4892 |
| WASF1 | 5834 |
| DOCK1 | 5903 |
| WIPF3 | 6386 |
| MYO10 | 6688 |
| PTK2 | 8088 |
Role of phospholipids in phagocytosis
| 1078 | |
|---|---|
| set | Role of phospholipids in phagocytosis |
| setSize | 64 |
| pANOVA | 6.61e-20 |
| s.dist | -0.66 |
| p.adjustANOVA | 4.36e-18 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| IGHV1-2 | -8953 |
| IGHV1-46 | -8910 |
| IGKV2D-28 | -8875 |
| IGHG4 | -8874 |
| IGKV3-11 | -8864 |
| IGKV1D-39 | -8828 |
| IGLV3-21 | -8806 |
| IGLV3-25 | -8773 |
| PIK3R2 | -8767 |
| IGHV3-33 | -8608 |
| IGLV2-14 | -8572 |
| PLD3 | -8311 |
| IGLV1-40 | -8088 |
| FCGR3A | -8055 |
| IGKV3-15 | -7403 |
| IGHV3-11 | -7017 |
| PRKCD | -6909 |
| PIK3R1 | -6564 |
| SYK | -6217 |
| ITPR3 | -5506 |
| FCGR2A | -4754 |
| IGKV1-33 | -4702 |
| PLPP5 | -4285 |
| PLD4 | -4193 |
| PLD1 | -3314 |
| FCGR1A | -2944 |
| CD247 | -834 |
| AHCYL1 | -485 |
| PIK3CB | -106 |
| PIK3CA | 2176 |
| PLD2 | 2287 |
| ITPR2 | 4036 |
| CD3G | 4272 |
| PLA2G6 | 5139 |
| PLCG1 | 5830 |
| PRKCE | 6762 |
| PLCG2 | 8985 |
| ITPR1 | 9487 |
Fcgamma receptor (FCGR) dependent phagocytosis
| 405 | |
|---|---|
| set | Fcgamma receptor (FCGR) dependent phagocytosis |
| setSize | 125 |
| pANOVA | 7.65e-20 |
| s.dist | -0.472 |
| p.adjustANOVA | 4.83e-18 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| IGHV1-2 | -8953 |
| IGHV1-46 | -8910 |
| IGKV2D-28 | -8875 |
| IGHG4 | -8874 |
| IGKV3-11 | -8864 |
| IGKV1D-39 | -8828 |
| FGR | -8811 |
| IGLV3-21 | -8806 |
| IGLV3-25 | -8773 |
| PIK3R2 | -8767 |
| IGHV3-33 | -8608 |
| WAS | -8588 |
| IGLV2-14 | -8572 |
| PLD3 | -8311 |
| HCK | -8242 |
| SRC | -8148 |
| IGLV1-40 | -8088 |
| FCGR3A | -8055 |
| LIMK1 | -7870 |
| BAIAP2 | -7839 |
| VAV1 | -7822 |
| ARPC1B | -7593 |
| IGKV3-15 | -7403 |
| GRB2 | -7191 |
| WASF2 | -7177 |
| CFL1 | -7166 |
| IGHV3-11 | -7017 |
| NCKIPSD | -6918 |
| PRKCD | -6909 |
| MYO9B | -6808 |
| ARPC4 | -6731 |
| MYH2 | -6671 |
| BTK | -6612 |
| PIK3R1 | -6564 |
| MAPK3 | -6329 |
| SYK | -6217 |
| BRK1 | -6144 |
| MYO1C | -5948 |
| NCKAP1L | -5878 |
| ARPC3 | -5798 |
| ELMO2 | -5690 |
| ITPR3 | -5506 |
| ACTB | -5073 |
| FYN | -4854 |
| FCGR2A | -4754 |
| ARPC1A | -4752 |
| IGKV1-33 | -4702 |
| ARPC2 | -4697 |
| NF2 | -4649 |
| PLPP5 | -4285 |
| PLD4 | -4193 |
| RAC1 | -3331 |
| PLD1 | -3314 |
| PAK1 | -3309 |
| CDC42 | -3206 |
| FCGR1A | -2944 |
| LYN | -2889 |
| ELMO1 | -2743 |
| WIPF2 | -2680 |
| CYFIP2 | -2546 |
| CYFIP1 | -1658 |
| ABL1 | -1625 |
| ARPC5 | -969 |
| ACTG1 | -959 |
| VAV2 | -840 |
| CD247 | -834 |
| AHCYL1 | -485 |
| PIK3CB | -106 |
| WIPF1 | 21 |
| MYO5A | 391 |
| NCK1 | 629 |
| ACTR2 | 1000 |
| HSP90AB1 | 1424 |
| MAPK1 | 1610 |
| VAV3 | 1970 |
| CRK | 1993 |
| PIK3CA | 2176 |
| PLD2 | 2287 |
| NCKAP1 | 2330 |
| WASF3 | 2959 |
| ABI2 | 3335 |
| ACTR3 | 3346 |
| HSP90AA1 | 3693 |
| ITPR2 | 4036 |
| ABI1 | 4070 |
| MYH9 | 4253 |
| CD3G | 4272 |
| WASL | 4892 |
| PLA2G6 | 5139 |
| PLCG1 | 5830 |
| WASF1 | 5834 |
| DOCK1 | 5903 |
| WIPF3 | 6386 |
| MYO10 | 6688 |
| PRKCE | 6762 |
| YES1 | 6926 |
| PTK2 | 8088 |
| PLCG2 | 8985 |
| ITPR1 | 9487 |
Adaptive Immune System
| 61 | |
|---|---|
| set | Adaptive Immune System |
| setSize | 718 |
| pANOVA | 1.88e-19 |
| s.dist | -0.198 |
| p.adjustANOVA | 1.14e-17 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGHM | -9118 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| SIGLEC7 | -9100 |
| IGHV2-5 | -9098 |
| NCF1 | -9092 |
| IGKC | -9087 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGHM | -9118 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| SIGLEC7 | -9100 |
| IGHV2-5 | -9098 |
| NCF1 | -9092 |
| IGKC | -9087 |
| IGHD | -9085 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| CD79A | -9036 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| SLAMF7 | -8988 |
| IGHV1-2 | -8953 |
| LILRA2 | -8939 |
| MLST8 | -8926 |
| OSCAR | -8923 |
| IGHV1-46 | -8910 |
| IGKV2D-28 | -8875 |
| CTSA | -8873 |
| CSK | -8867 |
| IGKV3-11 | -8864 |
| CD81 | -8856 |
| IGKV1D-39 | -8828 |
| IGLV3-21 | -8806 |
| CD99 | -8784 |
| CLEC4G | -8780 |
| HLA-DQA1 | -8774 |
| IGLV3-25 | -8773 |
| PIK3R2 | -8767 |
| CYBA | -8747 |
| CD4 | -8741 |
| TREML1 | -8715 |
| ASB13 | -8677 |
| SEC13 | -8653 |
| ITGB2 | -8620 |
| IGHV3-33 | -8608 |
| FBXW5 | -8591 |
| RNF220 | -8590 |
| WAS | -8588 |
| IGLV2-14 | -8572 |
| ITGB7 | -8556 |
| CTSB | -8493 |
| PRKACA | -8490 |
| LAIR1 | -8472 |
| AKT1 | -8448 |
| TREM1 | -8429 |
| PILRA | -8421 |
| SIGLEC1 | -8398 |
| MADCAM1 | -8397 |
| ATG7 | -8380 |
| LILRB2 | -8379 |
| PTPN6 | -8357 |
| TYROBP | -8356 |
| PSMD3 | -8328 |
| PPL | -8305 |
| IFI30 | -8275 |
| CD8B | -8225 |
| AP1B1 | -8173 |
| MRC2 | -8158 |
| PDCD1 | -8157 |
| DCTN1 | -8155 |
| PSMD8 | -8149 |
| SRC | -8148 |
| STUB1 | -8141 |
| SLAMF6 | -8138 |
| IGLV1-40 | -8088 |
| SIGLEC5 | -8058 |
| SEC61A1 | -8056 |
| FCGR3A | -8055 |
| LILRB3 | -8035 |
| MYD88 | -8007 |
| CD209 | -7967 |
| LILRB4 | -7957 |
| AP2M1 | -7945 |
| CTSD | -7893 |
| TAPBP | -7871 |
| AP2S1 | -7829 |
| SIPA1 | -7823 |
| VAV1 | -7822 |
| ITGB5 | -7819 |
| KEAP1 | -7807 |
| TRIM32 | -7764 |
| PDIA3 | -7754 |
| BTBD6 | -7737 |
| ARF1 | -7717 |
| PSMB10 | -7709 |
| DCTN3 | -7698 |
| CD300A | -7613 |
| ASB1 | -7607 |
| THOP1 | -7606 |
| PSMB5 | -7576 |
| UBE2M | -7541 |
| DNM1 | -7539 |
| VAMP8 | -7535 |
| KLC4 | -7532 |
| CUL7 | -7521 |
| ASB11 | -7514 |
| UBA1 | -7503 |
| UBE2J2 | -7410 |
| LILRB5 | -7407 |
| IGKV3-15 | -7403 |
| DCTN5 | -7397 |
| RILP | -7393 |
| AKT2 | -7377 |
| IKBKG | -7367 |
| HLA-DQB1 | -7344 |
| LRRC41 | -7324 |
| DCTN2 | -7295 |
| TREM2 | -7286 |
| PSME3 | -7280 |
| UBE2D4 | -7271 |
| PSMB2 | -7268 |
| GRB2 | -7191 |
| CAPZB | -7174 |
| LILRA6 | -7161 |
| CD74 | -7156 |
| LCK | -7148 |
| RNF130 | -7143 |
| PSMD2 | -7104 |
| SEC61B | -7068 |
| LGMN | -7062 |
| ANAPC11 | -7053 |
| HLA-DOA | -7051 |
| AP2A1 | -7041 |
| IGHV3-11 | -7017 |
| RAP1GAP2 | -7015 |
| SIGLEC9 | -7013 |
| PIANP | -6992 |
| PPP2R1A | -6964 |
| SIGLEC11 | -6957 |
| AP1S1 | -6952 |
| CD33 | -6926 |
| UBA52 | -6880 |
| CD28 | -6879 |
| VCAM1 | -6799 |
| S100A1 | -6798 |
| PJA1 | -6781 |
| RNF126 | -6777 |
| CD300C | -6768 |
| LAG3 | -6722 |
| PSMB6 | -6709 |
| DYNLL2 | -6690 |
| CALR | -6689 |
| HLA-DPB1 | -6679 |
| PSMB3 | -6647 |
| FBXW9 | -6624 |
| BTK | -6612 |
| ELOB | -6600 |
| AP1M1 | -6596 |
| FBXO2 | -6574 |
| PIK3R1 | -6564 |
| RNF123 | -6560 |
| PPIA | -6508 |
| PTPN22 | -6481 |
| DYNLL1 | -6465 |
| PSMD4 | -6452 |
| KIF22 | -6434 |
| HLA-DRA | -6414 |
| NCF4 | -6412 |
| ACTR1A | -6346 |
| HLA-DPA1 | -6339 |
| PSMF1 | -6332 |
| FBXL15 | -6290 |
| FCGR1B | -6274 |
| SEC61G | -6251 |
| SYK | -6217 |
| SIGLEC6 | -6204 |
| UBB | -6193 |
| MKRN1 | -6170 |
| CD14 | -6153 |
| PSMC5 | -6143 |
| AP2A2 | -6118 |
| SEC24C | -6100 |
| TRBC1 | -6095 |
| PSMA7 | -6082 |
| SIGLEC8 | -6076 |
| AP2B1 | -6058 |
| ACTR1B | -6022 |
| PSMB7 | -5953 |
| UBE2L3 | -5910 |
| PSMC4 | -5866 |
| FBXO44 | -5864 |
| PRR5 | -5863 |
| RAB7A | -5854 |
| TLR2 | -5828 |
| SPSB4 | -5797 |
| PPP2R5D | -5791 |
| PSMC3 | -5726 |
| UBAC1 | -5722 |
| UBE2F | -5708 |
| UBR4 | -5637 |
| SPSB2 | -5632 |
| TRIM21 | -5612 |
| LILRB1 | -5584 |
| ASB8 | -5552 |
| RNF4 | -5526 |
| ITPR3 | -5506 |
| ICAM5 | -5497 |
| HLA-DMB | -5489 |
| PSMB1 | -5473 |
| TRIM11 | -5415 |
| CD3E | -5364 |
| CTSS | -5358 |
| RAET1E | -5308 |
| SH3GL2 | -5270 |
| LCP2 | -5202 |
| UBE2L6 | -5197 |
| CD86 | -5191 |
| COLEC12 | -5183 |
| RNF25 | -5176 |
| PSMB4 | -5168 |
| MIB2 | -5157 |
| ASB6 | -5125 |
| HECTD3 | -5103 |
| HLA-DMA | -5092 |
| NFKBIB | -5076 |
| SEC22B | -5055 |
| KBTBD7 | -5035 |
| FBXL8 | -5033 |
| CTSL | -4981 |
| ERAP1 | -4972 |
| HRAS | -4955 |
| RBCK1 | -4932 |
| CD22 | -4929 |
| UBE2Z | -4878 |
| TRAC | -4873 |
| FBXO41 | -4858 |
| FYN | -4854 |
| EVL | -4849 |
| KLHL41 | -4791 |
| ZBTB16 | -4763 |
| RACGAP1 | -4762 |
| UBE2E3 | -4749 |
| SKP1 | -4737 |
| LRR1 | -4728 |
| CD8A | -4727 |
| NEDD4L | -4722 |
| IGKV1-33 | -4702 |
| FBXL18 | -4675 |
| CLTA | -4661 |
| PSMD9 | -4655 |
| TRIM41 | -4653 |
| HUWE1 | -4455 |
| RBX1 | -4435 |
| SEC31A | -4403 |
| HSPA5 | -4392 |
| DCTN6 | -4386 |
| DYNC1H1 | -4355 |
| FCGR2B | -4271 |
| VAMP3 | -4260 |
| PSMC2 | -4179 |
| CD300LF | -4120 |
| SAR1B | -4109 |
| LAT | -4104 |
| RELA | -4097 |
| KLHL22 | -4065 |
| FBXO27 | -4047 |
| FBXO7 | -4031 |
| PIK3AP1 | -4015 |
| MGRN1 | -4002 |
| PRKACB | -3946 |
| ORAI2 | -3933 |
| DNM2 | -3899 |
| FBXO9 | -3877 |
| CYBB | -3854 |
| PSMD10 | -3849 |
| BLK | -3800 |
| UBE2Q1 | -3785 |
| UNKL | -3770 |
| CTSF | -3736 |
| TRIB3 | -3731 |
| BLNK | -3695 |
| BTRC | -3694 |
| HLA-A | -3688 |
| AP1S2 | -3655 |
| CDC20 | -3613 |
| RNF7 | -3583 |
| RAF1 | -3561 |
| CD96 | -3514 |
| VASP | -3497 |
| UBE2E2 | -3486 |
| SIGLEC10 | -3480 |
| ASB5 | -3435 |
| ANAPC2 | -3380 |
| RAC1 | -3331 |
| PAK1 | -3309 |
| CD19 | -3284 |
| RNF34 | -3270 |
| PSMA6 | -3225 |
| CDC42 | -3206 |
| STX4 | -3195 |
| ITGA4 | -3150 |
| CCNF | -3122 |
| LY96 | -3104 |
| CDC26 | -3045 |
| UBE2V2 | -3043 |
| PSME1 | -3031 |
| PTPRJ | -2991 |
| FBXO6 | -2980 |
| TRIM4 | -2969 |
| FCGR1A | -2944 |
| LNX1 | -2928 |
| LYN | -2889 |
| AREL1 | -2834 |
| MAPKAP1 | -2829 |
| MYLIP | -2823 |
| UBE2D2 | -2735 |
| PSMD7 | -2731 |
| FBXO4 | -2716 |
| PPP2R5B | -2711 |
| PSMA5 | -2649 |
| PSMC1 | -2604 |
| CD3D | -2603 |
| RASGRP2 | -2558 |
| S100A8 | -2515 |
| CLTC | -2500 |
| ITGAV | -2473 |
| KLRB1 | -2458 |
| ANAPC7 | -2426 |
| SPSB1 | -2411 |
| FBXW11 | -2408 |
| KIF2A | -2396 |
| FZR1 | -2354 |
| PPP2CB | -2329 |
| FBXO17 | -2307 |
| ZNRF1 | -2287 |
| UBA7 | -2276 |
| ARIH2 | -2260 |
| TLR4 | -2238 |
| SH3KBP1 | -2230 |
| CTSO | -2186 |
| PTPRC | -2154 |
| PSMD14 | -2133 |
| KLC1 | -2130 |
| CD40 | -2074 |
| HLA-DQB2 | -2038 |
| HCST | -2012 |
| KLHL11 | -2004 |
| MAP3K14 | -1995 |
| B2M | -1976 |
| HLA-DRB1 | -1973 |
| KBTBD6 | -1943 |
| FBXO40 | -1930 |
| NFATC3 | -1875 |
| PSMD1 | -1782 |
| LILRA5 | -1773 |
| PSMA4 | -1756 |
| UBE2O | -1729 |
| TIRAP | -1629 |
| PSME2 | -1591 |
| TRAIP | -1589 |
| KLHL9 | -1561 |
| ANAPC10 | -1560 |
| TRIM50 | -1554 |
| UBOX5 | -1536 |
| LRSAM1 | -1533 |
| NCR3LG1 | -1489 |
| PSMD11 | -1483 |
| PSMD5 | -1433 |
| ANAPC5 | -1362 |
| NCF2 | -1349 |
| CTSH | -1301 |
| PSMA2 | -1286 |
| FBXW4 | -1204 |
| CTSC | -1185 |
| RNF114 | -1182 |
| SEC24D | -1154 |
| RNF41 | -1144 |
| CDC23 | -1090 |
| KIF3B | -1084 |
| FBXL19 | -1026 |
| FBXO10 | -1005 |
| MRC1 | -943 |
| CARD11 | -915 |
| FBXL5 | -865 |
| ORAI1 | -844 |
| ZNRF2 | -837 |
| CD247 | -834 |
| CBLB | -823 |
| HLA-H | -815 |
| RASGRP1 | -813 |
| CDC34 | -803 |
| CAPZA2 | -802 |
| PPP3CB | -797 |
| PSMD13 | -754 |
| TRIP12 | -687 |
| TRIM63 | -624 |
| MTOR | -561 |
| CANX | -540 |
| UBE2G2 | -536 |
| TLR1 | -517 |
| AHCYL1 | -485 |
| NFATC1 | -480 |
| UBE2R2 | -460 |
| UBE2K | -426 |
| ZAP70 | -398 |
| UBE3B | -397 |
| ACTR10 | -373 |
| FBXO21 | -329 |
| DTX3L | -291 |
| SH2D1A | -253 |
| PSMB8 | -235 |
| RNF14 | -201 |
| RNF6 | -166 |
| HLA-DQA2 | -146 |
| RAP1A | -109 |
| NFKBIE | -108 |
| PIK3CB | -106 |
| CD300LB | -68 |
| PSME4 | -48 |
| PSMD6 | 26 |
| PDPK1 | 33 |
| KIF15 | 35 |
| DCTN4 | 48 |
| UFL1 | 62 |
| TRIM39 | 83 |
| AP1G1 | 107 |
| CXADR | 117 |
| NFKBIA | 181 |
| UBE4A | 191 |
| PPP2R5C | 198 |
| RPS27A | 229 |
| UBE3C | 236 |
| KIF5A | 259 |
| KCTD7 | 290 |
| UBE2G1 | 327 |
| KBTBD8 | 348 |
| FBXL13 | 359 |
| TRIM69 | 367 |
| TLR6 | 378 |
| PSMA1 | 379 |
| PRKCB | 421 |
| UBE2A | 466 |
| NFKB1 | 503 |
| CDC16 | 578 |
| TRIM36 | 600 |
| NCK1 | 629 |
| CD226 | 648 |
| VHL | 652 |
| KLHL25 | 799 |
| RAP1B | 813 |
| THEM4 | 832 |
| PPP3CA | 858 |
| TRAF7 | 930 |
| SEC23A | 932 |
| INPP5D | 1076 |
| STIM1 | 1087 |
| KIF20A | 1125 |
| CD200R1 | 1185 |
| SOCS1 | 1191 |
| HLA-DOB | 1253 |
| FBXL3 | 1274 |
| FBXL14 | 1285 |
| CD274 | 1301 |
| MAP3K7 | 1306 |
| ASB7 | 1320 |
| KLRG1 | 1337 |
| PJA2 | 1387 |
| UBE3A | 1402 |
| DET1 | 1405 |
| CUL1 | 1406 |
| ICAM3 | 1443 |
| PIK3CD | 1455 |
| YWHAB | 1469 |
| PPP2R5E | 1485 |
| S100A9 | 1503 |
| TNFRSF14 | 1533 |
| UBE2E1 | 1544 |
| RNF213 | 1560 |
| ICAM2 | 1582 |
| CALM1 | 1638 |
| RBBP6 | 1706 |
| HLA-DRB5 | 1726 |
| KLC2 | 1731 |
| CAPZA1 | 1732 |
| UBE2N | 1734 |
| NRAS | 1742 |
| UBE2C | 1747 |
| PAK3 | 1749 |
| IKBKB | 1755 |
| FBXO22 | 1768 |
| GRAP2 | 1775 |
| ITGAL | 1798 |
| FBXL12 | 1810 |
| TAB2 | 1818 |
| RNF115 | 1854 |
| FBXW2 | 1926 |
| ICOSLG | 2001 |
| LILRA1 | 2083 |
| CLEC2D | 2089 |
| KIF11 | 2120 |
| SMURF1 | 2127 |
| UBE2B | 2133 |
| PIK3CA | 2176 |
| FBXW8 | 2188 |
| BTBD1 | 2212 |
| UBE2V1 | 2277 |
| SMURF2 | 2303 |
| CTLA4 | 2340 |
| LTN1 | 2367 |
| FKBP1A | 2371 |
| ASB15 | 2375 |
| CD300E | 2454 |
| YWHAZ | 2459 |
| RNF111 | 2478 |
| CHUK | 2486 |
| SIAH2 | 2522 |
| PAK2 | 2552 |
| DYNC1LI2 | 2656 |
| ASB16 | 2681 |
| PVR | 2719 |
| UBE3D | 2733 |
| HERC2 | 2845 |
| FBXL4 | 2850 |
| BLMH | 2879 |
| RNF144B | 2958 |
| C3 | 2977 |
| WWP1 | 2981 |
| IFITM1 | 2988 |
| HECTD2 | 3077 |
| KCTD6 | 3088 |
| BTN3A3 | 3091 |
| KIF2C | 3143 |
| FBXO30 | 3156 |
| DYNC1I2 | 3198 |
| KLHL20 | 3230 |
| UBC | 3246 |
| ELOC | 3260 |
| HECTD1 | 3278 |
| DAPP1 | 3291 |
| CD40LG | 3313 |
| CUL5 | 3316 |
| KLHL13 | 3381 |
| UBA3 | 3420 |
| PILRB | 3491 |
| CENPE | 3506 |
| PPP2CA | 3519 |
| TAP2 | 3546 |
| CD101 | 3558 |
| SEC24A | 3580 |
| PSMD12 | 3658 |
| UBE2J1 | 3661 |
| CUL2 | 3685 |
| PTPN11 | 3742 |
| UBE2D3 | 3753 |
| BTN3A2 | 3788 |
| PSMC6 | 3801 |
| KIF5B | 3823 |
| KRAS | 3903 |
| SEC24B | 3945 |
| NPEPPS | 3979 |
| NFATC2 | 3997 |
| ASB2 | 4032 |
| ITPR2 | 4036 |
| PRKCQ | 4076 |
| UBE2Q2 | 4114 |
| PSMB9 | 4121 |
| FBXO32 | 4176 |
| KLHL2 | 4179 |
| ENAH | 4229 |
| CD3G | 4272 |
| KIF3C | 4321 |
| BTN2A2 | 4378 |
| ANAPC1 | 4391 |
| UBA6 | 4398 |
| FBXL20 | 4403 |
| CDC27 | 4464 |
| HERC4 | 4466 |
| ITGB1 | 4542 |
| LNPEP | 4556 |
| ASB14 | 4566 |
| CUL3 | 4595 |
| FBXL7 | 4619 |
| FBXW12 | 4698 |
| HLA-E | 4804 |
| CD1C | 4814 |
| UBR2 | 4820 |
| HLA-B | 4836 |
| KIF18A | 4869 |
| ANAPC13 | 4885 |
| HERC1 | 4902 |
| ASB9 | 4957 |
| MAP3K8 | 4967 |
| KIF4A | 4972 |
| KLRK1 | 5011 |
| PSMA3 | 5077 |
| PDCD1LG2 | 5115 |
| SNAP23 | 5187 |
| HLA-F | 5232 |
| PAG1 | 5281 |
| HMGB1 | 5302 |
| SEC61A2 | 5305 |
| UBE2H | 5344 |
| RCHY1 | 5346 |
| SH3RF1 | 5370 |
| SEM1 | 5372 |
| UBE2S | 5380 |
| UBE2D1 | 5427 |
| DZIP3 | 5436 |
| AKT3 | 5437 |
| FBXO11 | 5446 |
| SOS1 | 5452 |
| PPP3R1 | 5668 |
| SPTBN2 | 5752 |
| ITCH | 5770 |
| CTSK | 5776 |
| TPP2 | 5781 |
| RLIM | 5796 |
| PLCG1 | 5830 |
| BTN3A1 | 5867 |
| ITK | 5899 |
| SELL | 5962 |
| UBA5 | 5967 |
| RNF138 | 5981 |
| TRPC1 | 6031 |
| GLMN | 6041 |
| KIF3A | 6090 |
| CD1D | 6125 |
| UBR1 | 6126 |
| MICA | 6191 |
| DYNC1LI1 | 6270 |
| NEDD4 | 6379 |
| FBXW7 | 6440 |
| CRTAM | 6467 |
| ULBP3 | 6532 |
| KIFAP3 | 6594 |
| FBXO31 | 6642 |
| TRIM37 | 6681 |
| KLHL5 | 6693 |
| GAN | 6694 |
| NECTIN2 | 6697 |
| MALT1 | 6698 |
| CD79B | 6744 |
| PIK3R3 | 6755 |
| OSBPL1A | 6793 |
| ICAM1 | 6879 |
| ANAPC4 | 6889 |
| MICB | 6901 |
| YES1 | 6926 |
| PTEN | 7006 |
| ERAP2 | 7021 |
| TAP1 | 7077 |
| LMO7 | 7131 |
| ASB3 | 7208 |
| BTNL9 | 7224 |
| CD34 | 7230 |
| TRAF6 | 7237 |
| UBE2W | 7287 |
| BTN2A1 | 7334 |
| HERC6 | 7336 |
| KLRD1 | 7367 |
| RICTOR | 7399 |
| KIF23 | 7413 |
| JAML | 7421 |
| KLHL42 | 7422 |
| KLHL21 | 7460 |
| MEX3C | 7544 |
| AP1S3 | 7562 |
| TRIM9 | 7667 |
| DYNC1I1 | 7687 |
| HLA-C | 7759 |
| ASB4 | 7855 |
| SKP2 | 7870 |
| TREML2 | 7872 |
| CD160 | 7878 |
| CD300LG | 7880 |
| RAPGEF3 | 7895 |
| REL | 8027 |
| CDH1 | 8078 |
| PPP2R5A | 8203 |
| RNF217 | 8239 |
| BCL10 | 8277 |
| FBXL22 | 8385 |
| PPP2R1B | 8460 |
| PRKG1 | 8537 |
| CLEC2B | 8571 |
| CD36 | 8666 |
| NPDC1 | 8705 |
| HECW2 | 8721 |
| CTSV | 8815 |
| RIPK2 | 8936 |
| PLCG2 | 8985 |
| RNF19B | 9051 |
| RASGRP3 | 9229 |
| FBXO15 | 9320 |
| SIAH1 | 9417 |
| KIF26A | 9425 |
| ITPR1 | 9487 |
| LONRF1 | 9493 |
| WSB1 | 9620 |
| KIF5C | 9732 |
| HERC3 | 9744 |
| RNF19A | 9756 |
| KLHL3 | 9836 |
| DNM3 | 9866 |
| HERC5 | 9894 |
| RAPGEF4 | 9960 |
| SOCS3 | 10041 |
| HACE1 | 10068 |
| RNF182 | 10102 |
| CD200 | 10146 |
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
| 79 | |
|---|---|
| set | Antigen activates B Cell Receptor (BCR) leading to generation of second messengers |
| setSize | 68 |
| pANOVA | 2.89e-19 |
| s.dist | -0.629 |
| p.adjustANOVA | 1.68e-17 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGHM | -9118 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGHD | -9085 |
| IGKV2-28 | -9071 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGHM | -9118 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGHD | -9085 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| CD79A | -9036 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| IGHV1-2 | -8953 |
| IGHV1-46 | -8910 |
| IGKV2D-28 | -8875 |
| IGKV3-11 | -8864 |
| IGKV1D-39 | -8828 |
| IGLV3-21 | -8806 |
| IGLV3-25 | -8773 |
| IGHV3-33 | -8608 |
| IGLV2-14 | -8572 |
| PTPN6 | -8357 |
| IGLV1-40 | -8088 |
| VAV1 | -7822 |
| IGKV3-15 | -7403 |
| GRB2 | -7191 |
| IGHV3-11 | -7017 |
| BTK | -6612 |
| PIK3R1 | -6564 |
| SYK | -6217 |
| ITPR3 | -5506 |
| CD22 | -4929 |
| FYN | -4854 |
| IGKV1-33 | -4702 |
| PIK3AP1 | -4015 |
| ORAI2 | -3933 |
| BLK | -3800 |
| BLNK | -3695 |
| CD19 | -3284 |
| LYN | -2889 |
| SH3KBP1 | -2230 |
| ORAI1 | -844 |
| AHCYL1 | -485 |
| NCK1 | 629 |
| STIM1 | 1087 |
| PIK3CD | 1455 |
| CALM1 | 1638 |
| DAPP1 | 3291 |
| ITPR2 | 4036 |
| SOS1 | 5452 |
| TRPC1 | 6031 |
| CD79B | 6744 |
| PLCG2 | 8985 |
| ITPR1 | 9487 |
Asparagine N-linked glycosylation
| 90 | |
|---|---|
| set | Asparagine N-linked glycosylation |
| setSize | 274 |
| pANOVA | 5.99e-19 |
| s.dist | -0.312 |
| p.adjustANOVA | 3.22e-17 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| ALG3 | -9024 |
| COPZ2 | -8971 |
| SERPINA1 | -8963 |
| KDELR1 | -8946 |
| UAP1 | -8907 |
| KDELR3 | -8886 |
| DPM2 | -8879 |
| SLC35C1 | -8876 |
| CTSA | -8873 |
| DOLK | -8850 |
| BET1L | -8849 |
| ST6GALNAC4 | -8835 |
| PMM2 | -8777 |
| NANS | -8733 |
| TMEM115 | -8729 |
| ST6GALNAC6 | -8684 |
| RAB1B | -8672 |
| SEC13 | -8653 |
| COPG1 | -8633 |
| GMPPB | -8623 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ALG3 | -9024 |
| COPZ2 | -8971 |
| SERPINA1 | -8963 |
| KDELR1 | -8946 |
| UAP1 | -8907 |
| KDELR3 | -8886 |
| DPM2 | -8879 |
| SLC35C1 | -8876 |
| CTSA | -8873 |
| DOLK | -8850 |
| BET1L | -8849 |
| ST6GALNAC4 | -8835 |
| PMM2 | -8777 |
| NANS | -8733 |
| TMEM115 | -8729 |
| ST6GALNAC6 | -8684 |
| RAB1B | -8672 |
| SEC13 | -8653 |
| COPG1 | -8633 |
| GMPPB | -8623 |
| DHDDS | -8593 |
| YKT6 | -8548 |
| TMED3 | -8546 |
| TMED9 | -8530 |
| COG8 | -8475 |
| RPN2 | -8394 |
| ANK3 | -8387 |
| COPE | -8360 |
| B4GALT2 | -8317 |
| ARF3 | -8293 |
| STX5 | -8241 |
| GANAB | -8218 |
| ALG12 | -8201 |
| GLB1 | -8189 |
| DCTN1 | -8155 |
| MPDU1 | -8150 |
| CD55 | -8080 |
| ALG1 | -8022 |
| SPTBN4 | -8000 |
| COPZ1 | -7972 |
| TRAPPC1 | -7966 |
| DOLPP1 | -7956 |
| LMAN2 | -7933 |
| AMFR | -7926 |
| DDOST | -7902 |
| KDELR2 | -7899 |
| MGAT1 | -7872 |
| DAD1 | -7820 |
| GOLGA2 | -7775 |
| PDIA3 | -7754 |
| ARF1 | -7717 |
| DCTN3 | -7698 |
| ST6GALNAC5 | -7660 |
| SYVN1 | -7632 |
| RENBP | -7615 |
| CTSZ | -7584 |
| SEC16A | -7580 |
| PPP6R1 | -7578 |
| RPN1 | -7545 |
| GFPT2 | -7530 |
| TRAPPC5 | -7491 |
| MOGS | -7465 |
| DCTN5 | -7397 |
| GMPPA | -7395 |
| ARFGAP1 | -7381 |
| DCTN2 | -7295 |
| STT3A | -7290 |
| EDEM2 | -7195 |
| OS9 | -7193 |
| CAPZB | -7174 |
| GFUS | -7164 |
| PMM1 | -7072 |
| MGAT4B | -6946 |
| UBA52 | -6880 |
| TMED2 | -6853 |
| COPA | -6837 |
| FUCA1 | -6706 |
| DYNLL2 | -6690 |
| CALR | -6689 |
| DPAGT1 | -6669 |
| ARF5 | -6661 |
| RNF5 | -6648 |
| MVD | -6623 |
| SLC17A5 | -6589 |
| ARFGAP2 | -6556 |
| COPG2 | -6550 |
| TRAPPC2L | -6498 |
| DYNLL1 | -6465 |
| DERL1 | -6431 |
| ACTR1A | -6346 |
| LMAN2L | -6325 |
| ALG2 | -6248 |
| GOSR2 | -6207 |
| UBB | -6193 |
| ST3GAL1 | -6158 |
| ENGASE | -6148 |
| CHST8 | -6133 |
| SEC24C | -6100 |
| NAGK | -5927 |
| NAPA | -5914 |
| ANK1 | -5844 |
| MAN1B1 | -5730 |
| ARF4 | -5692 |
| GBF1 | -5553 |
| TMED10 | -5519 |
| VCP | -5509 |
| TRAPPC3 | -5420 |
| MLEC | -5382 |
| PRKCSH | -5301 |
| FOLR1 | -5272 |
| CHST10 | -5170 |
| COL7A1 | -5075 |
| SEC22B | -5055 |
| MPI | -5037 |
| PREB | -4989 |
| RNF185 | -4812 |
| NEU1 | -4756 |
| NEU3 | -4741 |
| AMDHD2 | -4690 |
| FUOM | -4679 |
| NPL | -4519 |
| SEC31A | -4403 |
| DCTN6 | -4386 |
| DYNC1H1 | -4355 |
| TFG | -4337 |
| SEC22A | -4335 |
| COPB2 | -4312 |
| COG4 | -4189 |
| SAR1B | -4109 |
| TBC1D20 | -4050 |
| DPM3 | -3983 |
| SEC22C | -3930 |
| TRAPPC9 | -3743 |
| MAGT1 | -3673 |
| UGGT1 | -3622 |
| MGAT2 | -3597 |
| LMAN1 | -3539 |
| TGFA | -3504 |
| USO1 | -3487 |
| SPTB | -3234 |
| MAN2A2 | -3220 |
| EDEM3 | -3174 |
| MGAT5 | -3110 |
| PGM3 | -3025 |
| ALG5 | -2985 |
| FCSK | -2935 |
| MAN1A1 | -2863 |
| TRAPPC4 | -2838 |
| RFT1 | -2817 |
| SRD5A3 | -2797 |
| DERL2 | -2770 |
| NSF | -2666 |
| PSMC1 | -2604 |
| ARCN1 | -2503 |
| ALG8 | -2436 |
| TUSC3 | -2306 |
| ST8SIA4 | -2014 |
| UBXN1 | -1779 |
| COG6 | -1764 |
| GNPNAT1 | -1722 |
| CNIH1 | -1687 |
| ALG9 | -1588 |
| ALG11 | -1573 |
| SPTAN1 | -1454 |
| MANEA | -1432 |
| COG2 | -1422 |
| GMDS | -1304 |
| GFPT1 | -1256 |
| CTSC | -1185 |
| B4GALT4 | -1184 |
| SEC24D | -1154 |
| CSNK1D | -956 |
| COPB1 | -893 |
| GOLGB1 | -831 |
| F8 | -828 |
| CAPZA2 | -802 |
| COG1 | -751 |
| GORASP1 | -663 |
| B4GALT1 | -661 |
| NGLY1 | -653 |
| F5 | -627 |
| CANX | -540 |
| NUS1 | -501 |
| PPP6C | -407 |
| ACTR10 | -373 |
| MAN1A2 | -330 |
| MAN2A1 | -288 |
| SCFD1 | -136 |
| ALG10 | -89 |
| TMED7 | -86 |
| DCTN4 | 48 |
| TRAPPC6A | 58 |
| SEL1L | 121 |
| TRAPPC10 | 129 |
| SPTBN5 | 209 |
| RPS27A | 229 |
| RAD23B | 243 |
| ARFGAP3 | 381 |
| GOSR1 | 516 |
| MGAT4A | 612 |
| GNE | 621 |
| NAPG | 703 |
| COG7 | 714 |
| ST3GAL4 | 774 |
| ALG14 | 928 |
| SEC23A | 932 |
| RNF139 | 972 |
| ST3GAL3 | 1150 |
| MIA3 | 1620 |
| CMAS | 1623 |
| RAB1A | 1661 |
| CAPZA1 | 1732 |
| B4GALT5 | 1807 |
| DPM1 | 1909 |
| COG5 | 1992 |
| MGAT4C | 2130 |
| FPGT | 2142 |
| TRIM13 | 2646 |
| DYNC1LI2 | 2656 |
| NANP | 2777 |
| SEC23IP | 2953 |
| TRAPPC2 | 3092 |
| SLC35A1 | 3178 |
| DYNC1I2 | 3198 |
| UBC | 3246 |
| SEC24A | 3580 |
| EDEM1 | 3611 |
| SEC16B | 3690 |
| MAN1C1 | 3794 |
| NUDT14 | 3804 |
| ALG10B | 3876 |
| COG3 | 3893 |
| SEC24B | 3945 |
| GRIA1 | 4245 |
| ST3GAL5 | 4332 |
| ST6GAL1 | 4514 |
| ST3GAL2 | 4843 |
| TRAPPC6B | 4845 |
| MCFD2 | 4888 |
| B4GALT3 | 4889 |
| SPTBN1 | 5040 |
| RNF103 | 5131 |
| ALG13 | 5249 |
| ASGR2 | 5395 |
| PPP6R3 | 5531 |
| ST6GAL2 | 5571 |
| ST8SIA5 | 5624 |
| SPTBN2 | 5752 |
| CD59 | 6004 |
| UGGT2 | 6005 |
| MGAT3 | 6122 |
| DYNC1LI1 | 6270 |
| ASGR1 | 6280 |
| MARCHF6 | 6307 |
| B4GALNT2 | 6425 |
| MIA2 | 6675 |
| CNIH3 | 6900 |
| BET1 | 6923 |
| NAPB | 7024 |
| ANKRD28 | 7067 |
| ANK2 | 7369 |
| FUT8 | 7476 |
| DYNC1I1 | 7687 |
| B4GALT6 | 7825 |
| ST6GALNAC1 | 7860 |
| STX17 | 7909 |
| AREG | 7970 |
| ST8SIA1 | 8155 |
| ST3GAL6 | 8762 |
| ALG6 | 8828 |
| ST6GALNAC2 | 8874 |
| ST6GALNAC3 | 9031 |
| SPTA1 | 9241 |
| ST8SIA6 | 9759 |
Vesicle-mediated transport
| 1399 | |
|---|---|
| set | Vesicle-mediated transport |
| setSize | 644 |
| pANOVA | 5.99e-19 |
| s.dist | -0.206 |
| p.adjustANOVA | 3.22e-17 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHA2 | -9147 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| GJB6 | -9107 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| LDLRAP1 | -9086 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHA2 | -9147 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| GJB6 | -9107 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| LDLRAP1 | -9086 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| JCHAIN | -9063 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| IGHA1 | -9037 |
| LRP1 | -9029 |
| MARCO | -9019 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| GJB2 | -8996 |
| COPZ2 | -8971 |
| SERPINA1 | -8963 |
| IGHV1-2 | -8953 |
| KDELR1 | -8946 |
| COPS7A | -8927 |
| IGHV1-46 | -8910 |
| UBAP1 | -8894 |
| KDELR3 | -8886 |
| IGKV2D-28 | -8875 |
| IGKV3-11 | -8864 |
| BET1L | -8849 |
| IGKV1D-39 | -8828 |
| IGLV3-21 | -8806 |
| SURF4 | -8799 |
| TBC1D3 | -8789 |
| IGLV3-25 | -8773 |
| CD4 | -8741 |
| PLIN3 | -8737 |
| TMEM115 | -8729 |
| CCZ1 | -8679 |
| RAB1B | -8672 |
| APOB | -8671 |
| HYOU1 | -8670 |
| SEC13 | -8653 |
| COPG1 | -8633 |
| DNASE2 | -8614 |
| IGHV3-33 | -8608 |
| IGLV2-14 | -8572 |
| YKT6 | -8548 |
| TMED3 | -8546 |
| TMED9 | -8530 |
| FCHO1 | -8519 |
| RIN3 | -8516 |
| COG8 | -8475 |
| BTC | -8453 |
| AKT1 | -8448 |
| BIN1 | -8446 |
| ANK3 | -8387 |
| BLOC1S1 | -8375 |
| COPE | -8360 |
| SCARA5 | -8333 |
| TPD52L1 | -8297 |
| ARF3 | -8293 |
| EPN1 | -8268 |
| STX5 | -8241 |
| RAB36 | -8202 |
| AP1B1 | -8173 |
| RINL | -8169 |
| DCTN1 | -8155 |
| SRC | -8148 |
| IGLV1-40 | -8088 |
| CD55 | -8080 |
| SPTBN4 | -8000 |
| COPZ1 | -7972 |
| TRAPPC1 | -7966 |
| AP2M1 | -7945 |
| LMAN2 | -7933 |
| TXNDC5 | -7914 |
| KDELR2 | -7899 |
| DENND2D | -7848 |
| YWHAH | -7831 |
| AP2S1 | -7829 |
| FTL | -7828 |
| DENND1C | -7811 |
| GOLGA2 | -7775 |
| GPS1 | -7769 |
| HBEGF | -7744 |
| ARF1 | -7717 |
| DCTN3 | -7698 |
| EGFR | -7625 |
| GALNT2 | -7585 |
| CTSZ | -7584 |
| SEC16A | -7580 |
| PPP6R1 | -7578 |
| DNM1 | -7539 |
| VAMP8 | -7535 |
| KLC4 | -7532 |
| SNAPIN | -7510 |
| NEDD8 | -7504 |
| TRAPPC5 | -7491 |
| COPS6 | -7464 |
| VPS25 | -7443 |
| IGKV3-15 | -7403 |
| DCTN5 | -7397 |
| ARFGAP1 | -7381 |
| AKT2 | -7377 |
| SSC5D | -7339 |
| PIP5K1C | -7332 |
| BLOC1S3 | -7319 |
| ARFIP2 | -7312 |
| DCTN2 | -7295 |
| TBC1D13 | -7206 |
| GRB2 | -7191 |
| CAPZB | -7174 |
| CHMP2A | -7162 |
| AGPAT3 | -7146 |
| SH3GL1 | -7094 |
| TOR1A | -7061 |
| AP2A1 | -7041 |
| IGHV3-11 | -7017 |
| RAB11B | -7016 |
| APOE | -7009 |
| TBC1D24 | -6987 |
| GABARAP | -6974 |
| AP1S1 | -6952 |
| CHMP6 | -6927 |
| CHMP7 | -6920 |
| UBA52 | -6880 |
| GGA1 | -6867 |
| TMED2 | -6853 |
| COPA | -6837 |
| SNAP29 | -6830 |
| ARRB2 | -6809 |
| BLOC1S4 | -6800 |
| ARPC4 | -6731 |
| RAB5C | -6693 |
| DYNLL2 | -6690 |
| CALR | -6689 |
| HSPA8 | -6665 |
| ARF5 | -6661 |
| RIN1 | -6654 |
| SNF8 | -6634 |
| MON1A | -6605 |
| AP1M1 | -6596 |
| M6PR | -6563 |
| ARFGAP2 | -6556 |
| COPG2 | -6550 |
| TRAPPC2L | -6498 |
| TBC1D14 | -6480 |
| DYNLL1 | -6465 |
| FTH1 | -6455 |
| VPS4A | -6443 |
| KIF22 | -6434 |
| SLC2A8 | -6423 |
| DENND4B | -6406 |
| RAB5B | -6400 |
| HGS | -6399 |
| TOR1B | -6389 |
| DENND6B | -6387 |
| ACTR1A | -6346 |
| LMAN2L | -6325 |
| RAB41 | -6262 |
| EXOC7 | -6237 |
| CUX1 | -6213 |
| GOSR2 | -6207 |
| IGF2R | -6196 |
| UBB | -6193 |
| NECAP2 | -6135 |
| AP2A2 | -6118 |
| SEC24C | -6100 |
| TBC1D17 | -6078 |
| PRKAB1 | -6062 |
| AP2B1 | -6058 |
| TBC1D10B | -6019 |
| MYO1C | -5948 |
| GRK2 | -5941 |
| NAPA | -5914 |
| VAMP2 | -5893 |
| CHMP4B | -5859 |
| RAB7A | -5854 |
| ANK1 | -5844 |
| ARPC3 | -5798 |
| ARF4 | -5692 |
| CD163 | -5579 |
| GBF1 | -5553 |
| EXOC3 | -5549 |
| RAB8A | -5535 |
| TMED10 | -5519 |
| RAB32 | -5463 |
| TSG101 | -5436 |
| TRAPPC3 | -5420 |
| RAB7B | -5412 |
| STAB1 | -5397 |
| GJA3 | -5395 |
| CLTB | -5384 |
| TGOLN2 | -5360 |
| PACSIN2 | -5348 |
| NBAS | -5336 |
| SBF1 | -5325 |
| TBC1D2 | -5309 |
| POLG | -5283 |
| FOLR1 | -5272 |
| SH3GL2 | -5270 |
| APP | -5231 |
| COLEC12 | -5183 |
| VPS28 | -5178 |
| GCC1 | -5151 |
| GGA3 | -5136 |
| COL7A1 | -5075 |
| GABARAPL2 | -5074 |
| SEC22B | -5055 |
| PRKAG1 | -5017 |
| EREG | -5006 |
| PREB | -4989 |
| HPS1 | -4951 |
| AGFG1 | -4931 |
| ARL1 | -4905 |
| BNIP1 | -4794 |
| NAA38 | -4792 |
| GNS | -4788 |
| SYS1 | -4781 |
| RACGAP1 | -4762 |
| ARPC1A | -4752 |
| MASP1 | -4746 |
| IGKV1-33 | -4702 |
| ARPC2 | -4697 |
| CLTA | -4661 |
| RABEPK | -4412 |
| SEC31A | -4403 |
| CYTH4 | -4398 |
| DCTN6 | -4386 |
| RINT1 | -4371 |
| DYNC1H1 | -4355 |
| HSP90B1 | -4345 |
| EGF | -4342 |
| TFG | -4337 |
| SEC22A | -4335 |
| TBC1D16 | -4327 |
| COPB2 | -4312 |
| VAMP3 | -4260 |
| GGA2 | -4225 |
| COG4 | -4189 |
| SORT1 | -4178 |
| DVL2 | -4117 |
| SAR1B | -4109 |
| DAB2 | -4090 |
| TBC1D20 | -4050 |
| SEC22C | -3930 |
| DNM2 | -3899 |
| TRAPPC9 | -3743 |
| GJC2 | -3727 |
| CYTH3 | -3682 |
| AP1S2 | -3655 |
| EXOC4 | -3619 |
| GDI1 | -3546 |
| LMAN1 | -3539 |
| AP1G2 | -3522 |
| MADD | -3520 |
| CLVS2 | -3518 |
| MON1B | -3517 |
| TGFA | -3504 |
| USO1 | -3487 |
| TRIP11 | -3466 |
| RAC1 | -3331 |
| TRAPPC12 | -3328 |
| ULK1 | -3296 |
| SPTB | -3234 |
| MAN2A2 | -3220 |
| COPS7B | -3219 |
| STX4 | -3195 |
| DTNBP1 | -3092 |
| PLA2G4A | -3044 |
| ASPSCR1 | -3019 |
| KIFC2 | -2905 |
| USE1 | -2899 |
| MAN1A1 | -2863 |
| TRAPPC4 | -2838 |
| TBC1D10A | -2813 |
| GOLGA5 | -2812 |
| COPS3 | -2773 |
| MSR1 | -2726 |
| STX10 | -2707 |
| RABGEF1 | -2695 |
| NSF | -2666 |
| APOL1 | -2619 |
| GOLGA4 | -2618 |
| MVB12B | -2605 |
| CD3D | -2603 |
| YWHAQ | -2586 |
| VPS51 | -2528 |
| GAK | -2507 |
| ARCN1 | -2503 |
| CLTC | -2500 |
| YWHAE | -2405 |
| KIF2A | -2396 |
| AP4M1 | -2394 |
| MVB12A | -2344 |
| TFRC | -2336 |
| SH3KBP1 | -2230 |
| SCARB2 | -2224 |
| RAB35 | -2190 |
| KIF1B | -2181 |
| KLC1 | -2130 |
| SCOC | -2086 |
| TSC2 | -2013 |
| TBC1D25 | -1956 |
| CHMP4A | -1935 |
| RAB3GAP1 | -1876 |
| RIN2 | -1843 |
| COG6 | -1764 |
| CNIH1 | -1687 |
| ARRB1 | -1679 |
| VPS52 | -1662 |
| ARFRP1 | -1636 |
| UBQLN2 | -1583 |
| GDI2 | -1535 |
| YWHAG | -1528 |
| RAB9B | -1509 |
| SPTAN1 | -1454 |
| COG2 | -1422 |
| AP4B1 | -1398 |
| RAB10 | -1385 |
| AP3S1 | -1361 |
| SYTL1 | -1291 |
| GOLIM4 | -1241 |
| COPS2 | -1211 |
| CTSC | -1185 |
| SEC24D | -1154 |
| KIF3B | -1084 |
| COPS4 | -1031 |
| CHML | -983 |
| ARPC5 | -969 |
| CSNK1D | -956 |
| TBC1D8B | -951 |
| SNX18 | -946 |
| COPB1 | -893 |
| GOLGB1 | -831 |
| F8 | -828 |
| CAPZA2 | -802 |
| CLINT1 | -777 |
| COG1 | -751 |
| MAP1LC3B | -706 |
| GORASP1 | -663 |
| VAMP7 | -643 |
| F5 | -627 |
| RAB38 | -626 |
| ANKRD27 | -599 |
| RAB31 | -572 |
| COL1A2 | -557 |
| VPS4B | -506 |
| RGP1 | -494 |
| COLEC11 | -449 |
| KIF13B | -414 |
| PPP6C | -407 |
| RAB27B | -396 |
| ACTR10 | -373 |
| MAN1A2 | -330 |
| AP4E1 | -323 |
| VTA1 | -306 |
| MAN2A1 | -288 |
| STAM2 | -192 |
| SCFD1 | -136 |
| TBC1D10C | -97 |
| TMED7 | -86 |
| EPS15L1 | -56 |
| SNX2 | -36 |
| EXOC8 | 34 |
| KIF15 | 35 |
| DCTN4 | 48 |
| TRAPPC6A | 58 |
| VPS45 | 71 |
| ITSN2 | 81 |
| AP1G1 | 107 |
| BLOC1S6 | 110 |
| DENND1A | 126 |
| TRAPPC10 | 129 |
| YIPF6 | 196 |
| SPTBN5 | 209 |
| RPS27A | 229 |
| RAB9A | 231 |
| KIF5A | 259 |
| FNBP1 | 264 |
| KIF1C | 270 |
| ARFGAP3 | 381 |
| MYO5A | 391 |
| TRIP10 | 432 |
| VPS37D | 452 |
| ARF6 | 492 |
| GOSR1 | 516 |
| SAA1 | 558 |
| SYT11 | 596 |
| KIFC1 | 616 |
| NAPG | 703 |
| COG7 | 714 |
| CHMP2B | 829 |
| RAB4A | 839 |
| RHOQ | 847 |
| FZD4 | 867 |
| RAB18 | 879 |
| GJA5 | 902 |
| RAB3IL1 | 922 |
| SEC23A | 932 |
| TBC1D1 | 937 |
| ACTR2 | 1000 |
| COPS5 | 1035 |
| TMF1 | 1107 |
| KIF20A | 1125 |
| CTTN | 1139 |
| CHMP3 | 1232 |
| KIF20B | 1245 |
| PRKAG2 | 1283 |
| ADRB2 | 1284 |
| STX6 | 1288 |
| NECAP1 | 1297 |
| PAFAH1B3 | 1309 |
| BICD2 | 1355 |
| DENND5B | 1371 |
| SCARB1 | 1426 |
| YWHAB | 1469 |
| DENND2A | 1479 |
| PAFAH1B2 | 1516 |
| IL7R | 1521 |
| GRK3 | 1564 |
| RAB13 | 1575 |
| SBF2 | 1598 |
| MIA3 | 1620 |
| DENND3 | 1627 |
| CALM1 | 1638 |
| RAB1A | 1661 |
| ZW10 | 1669 |
| KIF16B | 1680 |
| KLC2 | 1731 |
| CAPZA1 | 1732 |
| EPN2 | 1754 |
| VPS37C | 1841 |
| CHM | 1855 |
| RAB14 | 1901 |
| OCRL | 1952 |
| RAB33B | 1966 |
| COG5 | 1992 |
| ACBD3 | 2059 |
| RAB6A | 2072 |
| KIF11 | 2120 |
| RALGAPB | 2138 |
| RAB3GAP2 | 2140 |
| UBQLN1 | 2159 |
| REPS2 | 2255 |
| PRKAA2 | 2305 |
| RAB43 | 2319 |
| CHMP5 | 2344 |
| COPS8 | 2419 |
| TPD52 | 2426 |
| YWHAZ | 2459 |
| RAB39A | 2479 |
| AP3B1 | 2517 |
| ALS2CL | 2591 |
| DYNC1LI2 | 2656 |
| DENND5A | 2703 |
| SFN | 2709 |
| VPS53 | 2735 |
| CHMP4C | 2917 |
| RALA | 2932 |
| SEC23IP | 2953 |
| VTI1A | 3057 |
| GALNT1 | 3072 |
| GJD3 | 3073 |
| KIF9 | 3076 |
| TRAPPC2 | 3092 |
| PACSIN3 | 3135 |
| KIF2C | 3143 |
| C2CD5 | 3158 |
| DYNC1I2 | 3198 |
| COL3A1 | 3207 |
| GCC2 | 3221 |
| TRAPPC11 | 3241 |
| UBC | 3246 |
| HPX | 3345 |
| ACTR3 | 3346 |
| CPD | 3376 |
| DENND1B | 3387 |
| PUM1 | 3414 |
| CBL | 3452 |
| CENPE | 3506 |
| SPARC | 3507 |
| SYNJ1 | 3523 |
| AP4S1 | 3536 |
| RHOBTB3 | 3578 |
| SEC24A | 3580 |
| HPS4 | 3612 |
| SLC2A4 | 3627 |
| TRAPPC8 | 3687 |
| SEC16B | 3690 |
| HSP90AA1 | 3693 |
| RABEP1 | 3741 |
| MAN1C1 | 3794 |
| KIF5B | 3823 |
| EXOC1 | 3838 |
| RAB6B | 3883 |
| COG3 | 3893 |
| SEC24B | 3945 |
| KIF18B | 3976 |
| FCHO2 | 4137 |
| RAB12 | 4152 |
| EXOC2 | 4164 |
| OPTN | 4175 |
| GRIA1 | 4245 |
| MYH9 | 4253 |
| CD3G | 4272 |
| RAB8B | 4281 |
| CLTCL1 | 4318 |
| KIF3C | 4321 |
| RABGAP1 | 4368 |
| VPS37A | 4490 |
| LNPEP | 4556 |
| NAA30 | 4646 |
| SNX5 | 4695 |
| VPS54 | 4703 |
| CYTH1 | 4753 |
| TRAPPC6B | 4845 |
| KIF18A | 4869 |
| HIP1 | 4883 |
| MCFD2 | 4888 |
| WASL | 4892 |
| STXBP3 | 4901 |
| EXOC5 | 4932 |
| SYT2 | 4944 |
| AGTR1 | 4947 |
| KIF4A | 4972 |
| SPTBN1 | 5040 |
| ITSN1 | 5092 |
| HP | 5104 |
| TBC1D15 | 5121 |
| DENND4C | 5133 |
| USP6NL | 5134 |
| PLA2G6 | 5139 |
| STAM | 5156 |
| SNAP23 | 5187 |
| GOLGA1 | 5206 |
| DENND6A | 5207 |
| EPS15 | 5214 |
| KIF21B | 5240 |
| TRAPPC13 | 5252 |
| STX18 | 5256 |
| SNX9 | 5263 |
| RAB27A | 5323 |
| TBC1D4 | 5334 |
| AVPR2 | 5390 |
| AKT3 | 5437 |
| RAB5A | 5503 |
| PAFAH1B1 | 5506 |
| PPP6R3 | 5531 |
| RAB3A | 5550 |
| COL4A2 | 5584 |
| VAMP4 | 5659 |
| WNT5A | 5694 |
| EXOC6 | 5696 |
| SH3D19 | 5700 |
| HBA1 | 5744 |
| SPTBN2 | 5752 |
| RIC1 | 5761 |
| HBB | 5795 |
| NAA35 | 5950 |
| CD59 | 6004 |
| DENND4A | 6015 |
| AAK1 | 6053 |
| KIF3A | 6090 |
| MYO6 | 6099 |
| KIF21A | 6112 |
| HSPH1 | 6134 |
| RAB21 | 6148 |
| DYNC1LI1 | 6270 |
| KIF26B | 6291 |
| GJA1 | 6316 |
| VPS36 | 6323 |
| COL1A1 | 6392 |
| REPS1 | 6493 |
| SCARF1 | 6559 |
| KIFAP3 | 6594 |
| TBC1D7 | 6608 |
| MIA2 | 6675 |
| STX16 | 6705 |
| RAB11A | 6758 |
| PRKAG3 | 6809 |
| CYTH2 | 6893 |
| CNIH3 | 6900 |
| BET1 | 6923 |
| DNAJC6 | 6967 |
| NAPB | 7024 |
| ANKRD28 | 7067 |
| ANK2 | 7369 |
| KIF23 | 7413 |
| RAB30 | 7434 |
| ALS2 | 7529 |
| AP1S3 | 7562 |
| CCZ1B | 7632 |
| KIF6 | 7647 |
| DYNC1I1 | 7687 |
| SYNJ2 | 7815 |
| STX17 | 7909 |
| PRKAB2 | 7959 |
| AREG | 7970 |
| GAPVD1 | 7972 |
| BICD1 | 8045 |
| TF | 8137 |
| AMPH | 8140 |
| PICALM | 8264 |
| VPS37B | 8331 |
| GJA4 | 8518 |
| KIF27 | 8521 |
| TSC1 | 8549 |
| PIK3C2A | 8597 |
| KIF19 | 8629 |
| STON2 | 8637 |
| CD36 | 8666 |
| STAB2 | 8771 |
| COL4A1 | 8797 |
| RAB3IP | 8812 |
| RALGAPA2 | 8867 |
| LRP2 | 9056 |
| HIP1R | 9194 |
| SPTA1 | 9241 |
| STON1 | 9358 |
| GJC1 | 9421 |
| KIF26A | 9425 |
| TJP1 | 9452 |
| SYT1 | 9515 |
| DENND2C | 9601 |
| KIF5C | 9732 |
| TACR1 | 9761 |
| DNM3 | 9866 |
| LDLR | 9925 |
| SGIP1 | 10053 |
| FNBP1L | 10088 |
FCERI mediated NF-kB activation
| 382 | |
|---|---|
| set | FCERI mediated NF-kB activation |
| setSize | 112 |
| pANOVA | 1.61e-18 |
| s.dist | -0.48 |
| p.adjustANOVA | 8.32e-17 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| IGHV1-2 | -8953 |
| IGHV1-46 | -8910 |
| IGKV2D-28 | -8875 |
| IGKV3-11 | -8864 |
| IGKV1D-39 | -8828 |
| IGLV3-21 | -8806 |
| IGLV3-25 | -8773 |
| IGHV3-33 | -8608 |
| IGLV2-14 | -8572 |
| PSMD3 | -8328 |
| PSMD8 | -8149 |
| IGLV1-40 | -8088 |
| RASGRP4 | -7795 |
| PSMB10 | -7709 |
| PSMB5 | -7576 |
| IGKV3-15 | -7403 |
| IKBKG | -7367 |
| PSME3 | -7280 |
| PSMB2 | -7268 |
| PSMD2 | -7104 |
| IGHV3-11 | -7017 |
| UBA52 | -6880 |
| PSMB6 | -6709 |
| PSMB3 | -6647 |
| PSMD4 | -6452 |
| TAB1 | -6350 |
| PSMF1 | -6332 |
| UBB | -6193 |
| PSMC5 | -6143 |
| PSMA7 | -6082 |
| PSMB7 | -5953 |
| PSMC4 | -5866 |
| PSMC3 | -5726 |
| PSMB1 | -5473 |
| PSMB4 | -5168 |
| SKP1 | -4737 |
| IGKV1-33 | -4702 |
| PSMD9 | -4655 |
| PSMC2 | -4179 |
| RELA | -4097 |
| PSMD10 | -3849 |
| BTRC | -3694 |
| PSMA6 | -3225 |
| PSME1 | -3031 |
| LYN | -2889 |
| UBE2D2 | -2735 |
| PSMD7 | -2731 |
| PSMA5 | -2649 |
| PSMC1 | -2604 |
| RASGRP2 | -2558 |
| FBXW11 | -2408 |
| PSMD14 | -2133 |
| PSMD1 | -1782 |
| PSMA4 | -1756 |
| PSME2 | -1591 |
| PSMD11 | -1483 |
| PSMD5 | -1433 |
| PSMA2 | -1286 |
| CARD11 | -915 |
| RASGRP1 | -813 |
| CDC34 | -803 |
| PSMD13 | -754 |
| PSMB8 | -235 |
| PSME4 | -48 |
| PSMD6 | 26 |
| PDPK1 | 33 |
| NFKBIA | 181 |
| RPS27A | 229 |
| PSMA1 | 379 |
| NFKB1 | 503 |
| MAP3K7 | 1306 |
| CUL1 | 1406 |
| UBE2N | 1734 |
| IKBKB | 1755 |
| TAB2 | 1818 |
| UBE2V1 | 2277 |
| CHUK | 2486 |
| UBC | 3246 |
| PSMD12 | 3658 |
| PSMC6 | 3801 |
| PRKCQ | 4076 |
| PSMB9 | 4121 |
| TAB3 | 4183 |
| PSMA3 | 5077 |
| SEM1 | 5372 |
| UBE2D1 | 5427 |
| MALT1 | 6698 |
| TRAF6 | 7237 |
| BCL10 | 8277 |
The citric acid (TCA) cycle and respiratory electron transport
| 1315 | |
|---|---|
| set | The citric acid (TCA) cycle and respiratory electron transport |
| setSize | 172 |
| pANOVA | 1.95e-18 |
| s.dist | -0.387 |
| p.adjustANOVA | 9.76e-17 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| BSG | -8711 |
| ACO2 | -8665 |
| SURF1 | -8554 |
| NDUFAF3 | -8511 |
| NDUFA11 | -8504 |
| CYC1 | -8353 |
| MDH2 | -8286 |
| COX8A | -8260 |
| OGDH | -8244 |
| TACO1 | -8234 |
| ATP5MF | -8232 |
| ATP5F1D | -8212 |
| ETFB | -8156 |
| UQCRC1 | -7995 |
| NDUFA13 | -7854 |
| NDUFB10 | -7825 |
| RXRA | -7774 |
| NDUFS7 | -7728 |
| UQCR10 | -7703 |
| NDUFB7 | -7699 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| BSG | -8711 |
| ACO2 | -8665 |
| SURF1 | -8554 |
| NDUFAF3 | -8511 |
| NDUFA11 | -8504 |
| CYC1 | -8353 |
| MDH2 | -8286 |
| COX8A | -8260 |
| OGDH | -8244 |
| TACO1 | -8234 |
| ATP5MF | -8232 |
| ATP5F1D | -8212 |
| ETFB | -8156 |
| UQCRC1 | -7995 |
| NDUFA13 | -7854 |
| NDUFB10 | -7825 |
| RXRA | -7774 |
| NDUFS7 | -7728 |
| UQCR10 | -7703 |
| NDUFB7 | -7699 |
| NDUFS8 | -7687 |
| SDHA | -7652 |
| NDUFC1 | -7608 |
| ATP5ME | -7594 |
| NDUFA1 | -7540 |
| UQCRFS1 | -7522 |
| COX6B1 | -7448 |
| NDUFA6 | -7341 |
| GSTZ1 | -7252 |
| ATP5MC1 | -7251 |
| IDH3G | -7247 |
| PDK2 | -7246 |
| PDPR | -7219 |
| COX6A1 | -7180 |
| NDUFC2 | -7108 |
| HAGH | -7018 |
| UQCR11 | -6919 |
| SLC16A3 | -6876 |
| ATP5MC3 | -6841 |
| COX5B | -6747 |
| COX5A | -6735 |
| FAHD1 | -6732 |
| NDUFA3 | -6716 |
| SDHC | -6686 |
| NDUFA4 | -6655 |
| NDUFA8 | -6633 |
| ATP5MC2 | -6628 |
| NDUFS5 | -6581 |
| MT-ND6 | -6516 |
| ATP5F1E | -6502 |
| NDUFB11 | -6495 |
| CS | -6457 |
| COX7B | -6445 |
| NDUFV3 | -6428 |
| SDHB | -6352 |
| UCP2 | -6186 |
| VDAC1 | -6184 |
| NDUFB4 | -6053 |
| UQCRQ | -6043 |
| NDUFA2 | -6040 |
| NDUFB2 | -5967 |
| MPC2 | -5958 |
| NDUFS3 | -5954 |
| ATP5F1A | -5919 |
| NDUFAB1 | -5886 |
| MT-ND5 | -5735 |
| NDUFB3 | -5630 |
| ATP5PD | -5586 |
| NDUFB8 | -5569 |
| ATP5PF | -5543 |
| NDUFS6 | -5537 |
| NDUFAF4 | -5432 |
| COX7C | -5326 |
| SCO1 | -5322 |
| COX4I1 | -5248 |
| ATP5F1B | -5140 |
| PDHB | -5081 |
| NDUFB9 | -5052 |
| PPARD | -5034 |
| SCO2 | -4979 |
| COX19 | -4867 |
| MPC1 | -4820 |
| DLST | -4766 |
| COX16 | -4673 |
| COX14 | -4545 |
| ATP5MG | -4489 |
| ATP5PB | -4467 |
| ECSIT | -4451 |
| NDUFV1 | -4257 |
| IDH2 | -4245 |
| COX6C | -4240 |
| ATP5PO | -4216 |
| TMEM186 | -4208 |
| NDUFS4 | -4157 |
| NDUFAF1 | -4070 |
| TIMMDC1 | -4054 |
| NDUFB1 | -4014 |
| NDUFV2 | -3987 |
| ME2 | -3808 |
| MT-ATP8 | -3771 |
| IDH3B | -3733 |
| ACAD9 | -3714 |
| NDUFA7 | -3704 |
| GLO1 | -3465 |
| COX11 | -3330 |
| LDHA | -3223 |
| TRAP1 | -3119 |
| ATP5F1C | -3076 |
| NDUFB6 | -2896 |
| NDUFAF2 | -2788 |
| FH | -2732 |
| UQCRH | -2661 |
| PDHA1 | -2529 |
| SUCLG1 | -2318 |
| NUBPL | -2171 |
| COQ10A | -1825 |
| COX7A2L | -1534 |
| NDUFAF6 | -1480 |
| ETFA | -1469 |
| NDUFA5 | -1323 |
| UCP3 | -1280 |
| IDH3A | -1272 |
| NDUFA12 | -1250 |
| MT-CO3 | -1115 |
| COX18 | -1013 |
| MT-CO2 | -988 |
| SUCLA2 | -529 |
| NDUFB5 | -429 |
| D2HGDH | -341 |
| NDUFS1 | -297 |
| SLC16A1 | -162 |
| MT-ND4 | -94 |
| DMAC2L | -25 |
| DLAT | 403 |
| MT-ND2 | 425 |
| UQCRC2 | 468 |
| MT-CO1 | 720 |
| PDK3 | 1048 |
| MT-ATP6 | 1105 |
| UQCRB | 1227 |
| ME1 | 1234 |
| SLC16A8 | 1763 |
| NDUFAF7 | 1789 |
| COA1 | 1872 |
| MT-ND3 | 1944 |
| ADHFE1 | 1961 |
| TMEM126B | 2158 |
| DLD | 2572 |
| PDP2 | 2666 |
| PDK4 | 2727 |
| NNT | 2790 |
| SDHD | 3003 |
| ETFDH | 3008 |
| NDUFS2 | 3010 |
| SLC25A14 | 3046 |
| NDUFA9 | 3450 |
| NDUFA10 | 3483 |
| SUCLG2 | 3699 |
| MT-ND1 | 3710 |
| LRPPRC | 4418 |
| PDHX | 4872 |
| LDHB | 5058 |
| MT-CYB | 5619 |
| ME3 | 6390 |
| PDP1 | 7094 |
| CYCS | 7385 |
| NDUFAF5 | 7395 |
| COQ10B | 7585 |
| COX20 | 7745 |
| L2HGDH | 7898 |
| SLC25A27 | 8962 |
| PDK1 | 9206 |
Signaling by the B Cell Receptor (BCR)
| 1228 | |
|---|---|
| set | Signaling by the B Cell Receptor (BCR) |
| setSize | 146 |
| pANOVA | 3.89e-18 |
| s.dist | -0.416 |
| p.adjustANOVA | 1.88e-16 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGHM | -9118 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGHD | -9085 |
| IGKV2-28 | -9071 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGHM | -9118 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGHD | -9085 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| CD79A | -9036 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| IGHV1-2 | -8953 |
| IGHV1-46 | -8910 |
| IGKV2D-28 | -8875 |
| IGKV3-11 | -8864 |
| IGKV1D-39 | -8828 |
| IGLV3-21 | -8806 |
| IGLV3-25 | -8773 |
| IGHV3-33 | -8608 |
| IGLV2-14 | -8572 |
| PTPN6 | -8357 |
| PSMD3 | -8328 |
| PSMD8 | -8149 |
| IGLV1-40 | -8088 |
| VAV1 | -7822 |
| PSMB10 | -7709 |
| PSMB5 | -7576 |
| IGKV3-15 | -7403 |
| IKBKG | -7367 |
| PSME3 | -7280 |
| PSMB2 | -7268 |
| GRB2 | -7191 |
| PSMD2 | -7104 |
| IGHV3-11 | -7017 |
| UBA52 | -6880 |
| PSMB6 | -6709 |
| PSMB3 | -6647 |
| BTK | -6612 |
| PIK3R1 | -6564 |
| PPIA | -6508 |
| PSMD4 | -6452 |
| PSMF1 | -6332 |
| SYK | -6217 |
| UBB | -6193 |
| PSMC5 | -6143 |
| PSMA7 | -6082 |
| PSMB7 | -5953 |
| PSMC4 | -5866 |
| PSMC3 | -5726 |
| ITPR3 | -5506 |
| PSMB1 | -5473 |
| PSMB4 | -5168 |
| NFKBIB | -5076 |
| HRAS | -4955 |
| CD22 | -4929 |
| FYN | -4854 |
| SKP1 | -4737 |
| IGKV1-33 | -4702 |
| PSMD9 | -4655 |
| PSMC2 | -4179 |
| RELA | -4097 |
| PIK3AP1 | -4015 |
| ORAI2 | -3933 |
| PSMD10 | -3849 |
| BLK | -3800 |
| BLNK | -3695 |
| BTRC | -3694 |
| CD19 | -3284 |
| PSMA6 | -3225 |
| PSME1 | -3031 |
| LYN | -2889 |
| PSMD7 | -2731 |
| PSMA5 | -2649 |
| PSMC1 | -2604 |
| FBXW11 | -2408 |
| SH3KBP1 | -2230 |
| PSMD14 | -2133 |
| NFATC3 | -1875 |
| PSMD1 | -1782 |
| PSMA4 | -1756 |
| PSME2 | -1591 |
| PSMD11 | -1483 |
| PSMD5 | -1433 |
| PSMA2 | -1286 |
| CARD11 | -915 |
| ORAI1 | -844 |
| RASGRP1 | -813 |
| PPP3CB | -797 |
| PSMD13 | -754 |
| AHCYL1 | -485 |
| NFATC1 | -480 |
| PSMB8 | -235 |
| NFKBIE | -108 |
| PSME4 | -48 |
| PSMD6 | 26 |
| NFKBIA | 181 |
| RPS27A | 229 |
| PSMA1 | 379 |
| PRKCB | 421 |
| NFKB1 | 503 |
| NCK1 | 629 |
| PPP3CA | 858 |
| STIM1 | 1087 |
| MAP3K7 | 1306 |
| CUL1 | 1406 |
| PIK3CD | 1455 |
| CALM1 | 1638 |
| NRAS | 1742 |
| IKBKB | 1755 |
| FKBP1A | 2371 |
| CHUK | 2486 |
| UBC | 3246 |
| DAPP1 | 3291 |
| PSMD12 | 3658 |
| PSMC6 | 3801 |
| KRAS | 3903 |
| NFATC2 | 3997 |
| ITPR2 | 4036 |
| PSMB9 | 4121 |
| PSMA3 | 5077 |
| SEM1 | 5372 |
| SOS1 | 5452 |
| PPP3R1 | 5668 |
| TRPC1 | 6031 |
| MALT1 | 6698 |
| CD79B | 6744 |
| REL | 8027 |
| BCL10 | 8277 |
| PLCG2 | 8985 |
| RASGRP3 | 9229 |
| ITPR1 | 9487 |
Binding and Uptake of Ligands by Scavenger Receptors
| 115 | |
|---|---|
| set | Binding and Uptake of Ligands by Scavenger Receptors |
| setSize | 74 |
| pANOVA | 1.62e-17 |
| s.dist | -0.572 |
| p.adjustANOVA | 7.59e-16 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHA2 | -9147 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHA2 | -9147 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| JCHAIN | -9063 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| IGHA1 | -9037 |
| LRP1 | -9029 |
| MARCO | -9019 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| IGHV1-2 | -8953 |
| IGHV1-46 | -8910 |
| IGKV2D-28 | -8875 |
| IGKV3-11 | -8864 |
| IGKV1D-39 | -8828 |
| IGLV3-21 | -8806 |
| IGLV3-25 | -8773 |
| APOB | -8671 |
| HYOU1 | -8670 |
| IGHV3-33 | -8608 |
| IGLV2-14 | -8572 |
| SCARA5 | -8333 |
| IGLV1-40 | -8088 |
| FTL | -7828 |
| IGKV3-15 | -7403 |
| SSC5D | -7339 |
| IGHV3-11 | -7017 |
| APOE | -7009 |
| CALR | -6689 |
| FTH1 | -6455 |
| CD163 | -5579 |
| STAB1 | -5397 |
| COLEC12 | -5183 |
| MASP1 | -4746 |
| IGKV1-33 | -4702 |
| HSP90B1 | -4345 |
| MSR1 | -2726 |
| APOL1 | -2619 |
| COL1A2 | -557 |
| COLEC11 | -449 |
| SAA1 | 558 |
| SCARB1 | 1426 |
| COL3A1 | 3207 |
| HPX | 3345 |
| SPARC | 3507 |
| HSP90AA1 | 3693 |
| HP | 5104 |
| COL4A2 | 5584 |
| HBA1 | 5744 |
| HBB | 5795 |
| HSPH1 | 6134 |
| COL1A1 | 6392 |
| SCARF1 | 6559 |
| CD36 | 8666 |
| STAB2 | 8771 |
| COL4A1 | 8797 |
Post-translational protein modification
| 874 | |
|---|---|
| set | Post-translational protein modification |
| setSize | 1230 |
| pANOVA | 2.98e-17 |
| s.dist | -0.144 |
| p.adjustANOVA | 1.35e-15 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| MUC20 | -9146 |
| PENK | -9122 |
| RTN4RL1 | -9073 |
| ADAMTSL5 | -9072 |
| MELTF | -9059 |
| ALG3 | -9024 |
| B3GNT9 | -8999 |
| GALNT10 | -8989 |
| IGFBP1 | -8984 |
| COPZ2 | -8971 |
| SERPINA1 | -8963 |
| LTBP1 | -8961 |
| KDELR1 | -8946 |
| RPA1 | -8931 |
| COPS7A | -8927 |
| SBSPON | -8920 |
| CKAP4 | -8916 |
| UAP1 | -8907 |
| BMP4 | -8893 |
| KDELR3 | -8886 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MUC20 | -9146.0 |
| PENK | -9122.0 |
| RTN4RL1 | -9073.0 |
| ADAMTSL5 | -9072.0 |
| MELTF | -9059.0 |
| ALG3 | -9024.0 |
| B3GNT9 | -8999.0 |
| GALNT10 | -8989.0 |
| IGFBP1 | -8984.0 |
| COPZ2 | -8971.0 |
| SERPINA1 | -8963.0 |
| LTBP1 | -8961.0 |
| KDELR1 | -8946.0 |
| RPA1 | -8931.0 |
| COPS7A | -8927.0 |
| SBSPON | -8920.0 |
| CKAP4 | -8916.0 |
| UAP1 | -8907.0 |
| BMP4 | -8893.0 |
| KDELR3 | -8886.0 |
| DPM2 | -8879.0 |
| SLC35C1 | -8876.0 |
| CTSA | -8873.0 |
| SEMA5A | -8863.0 |
| DOLK | -8850.0 |
| BET1L | -8849.0 |
| ST6GALNAC4 | -8835.0 |
| DAG1 | -8830.0 |
| P4HB | -8801.0 |
| TIMP1 | -8781.0 |
| PMM2 | -8777.0 |
| FN1 | -8771.0 |
| LY6D | -8763.0 |
| NANS | -8733.0 |
| TMEM115 | -8729.0 |
| NUP210 | -8727.0 |
| APLP2 | -8697.0 |
| RNF135 | -8690.0 |
| ST6GALNAC6 | -8684.0 |
| ASB13 | -8677.0 |
| RAB1B | -8672.0 |
| APOB | -8671.0 |
| SEC13 | -8653.0 |
| COPG1 | -8633.0 |
| MEN1 | -8631.0 |
| GMPPB | -8623.0 |
| PIGT | -8609.0 |
| DHDDS | -8593.0 |
| FBXW5 | -8591.0 |
| THSD4 | -8579.0 |
| B4GAT1 | -8568.0 |
| YKT6 | -8548.0 |
| TMED3 | -8546.0 |
| PEX10 | -8545.0 |
| TMED9 | -8530.0 |
| JOSD2 | -8510.0 |
| UCHL1 | -8502.0 |
| COG8 | -8475.0 |
| COMMD9 | -8460.0 |
| NCOR2 | -8458.0 |
| TTLL12 | -8454.0 |
| PIGQ | -8426.0 |
| MCRS1 | -8402.0 |
| RPN2 | -8394.0 |
| ANK3 | -8387.0 |
| COPE | -8360.0 |
| ADAMTS15 | -8355.0 |
| PSMD3 | -8328.0 |
| MUL1 | -8318.0 |
| B4GALT2 | -8317.0 |
| ARF3 | -8293.0 |
| ADAMTS5 | -8283.0 |
| TGFB1 | -8281.0 |
| FN3KRP | -8270.0 |
| FAM20C | -8253.0 |
| FUCA2 | -8249.0 |
| STX5 | -8241.0 |
| ADAMTS17 | -8231.0 |
| GANAB | -8218.0 |
| RAB36 | -8202.0 |
| ALG12 | -8201.0 |
| GLB1 | -8189.0 |
| GALNT5 | -8187.0 |
| LY6K | -8165.0 |
| ETFB | -8156.0 |
| DCTN1 | -8155.0 |
| MPDU1 | -8150.0 |
| PSMD8 | -8149.0 |
| DPH2 | -8106.0 |
| POMGNT2 | -8105.0 |
| DCAF11 | -8082.0 |
| CD55 | -8080.0 |
| GPAA1 | -8025.0 |
| ALG1 | -8022.0 |
| SPTBN4 | -8000.0 |
| TADA3 | -7998.0 |
| UBD | -7988.0 |
| NEURL2 | -7982.0 |
| SUMF2 | -7981.0 |
| UCHL3 | -7978.0 |
| COPZ1 | -7972.0 |
| TRAPPC1 | -7966.0 |
| RNF181 | -7961.0 |
| DOLPP1 | -7956.0 |
| LMAN2 | -7933.0 |
| AMFR | -7926.0 |
| ADAMTSL3 | -7925.0 |
| C1GALT1 | -7908.0 |
| DDOST | -7902.0 |
| KDELR2 | -7899.0 |
| POM121C | -7894.0 |
| EEF2KMT | -7874.0 |
| MGAT1 | -7872.0 |
| USP5 | -7869.0 |
| SUMF1 | -7868.0 |
| DAD1 | -7820.0 |
| KEAP1 | -7807.0 |
| GOLGA2 | -7775.0 |
| RXRA | -7774.0 |
| TPR | -7773.0 |
| GPS1 | -7769.0 |
| PDIA3 | -7754.0 |
| OTUB1 | -7741.0 |
| BTBD6 | -7737.0 |
| ARF1 | -7717.0 |
| PSMB10 | -7709.0 |
| DCTN3 | -7698.0 |
| FOLR2 | -7688.0 |
| ADAMTSL4 | -7685.0 |
| ST6GALNAC5 | -7660.0 |
| SYVN1 | -7632.0 |
| FKBP8 | -7629.0 |
| RAD23A | -7624.0 |
| RENBP | -7615.0 |
| ASB1 | -7607.0 |
| TUBA1C | -7604.0 |
| PNPLA2 | -7596.0 |
| GALNT2 | -7585.0 |
| CTSZ | -7584.0 |
| SEC16A | -7580.0 |
| PPP6R1 | -7578.0 |
| PSMB5 | -7576.0 |
| TMEM129 | -7565.0 |
| USP19 | -7559.0 |
| MUC4 | -7552.0 |
| RPN1 | -7545.0 |
| TUBA1B | -7542.0 |
| UBE2M | -7541.0 |
| GFPT2 | -7530.0 |
| CUL7 | -7521.0 |
| DDB1 | -7515.0 |
| ASB11 | -7514.0 |
| NEDD8 | -7504.0 |
| UBA1 | -7503.0 |
| TRAPPC5 | -7491.0 |
| MOGS | -7465.0 |
| COPS6 | -7464.0 |
| SUMO3 | -7463.0 |
| TTLL1 | -7460.0 |
| WDTC1 | -7452.0 |
| ARSA | -7432.0 |
| UBE2J2 | -7410.0 |
| DCTN5 | -7397.0 |
| GMPPA | -7395.0 |
| ARFGAP1 | -7381.0 |
| L3MBTL2 | -7374.0 |
| PIGS | -7370.0 |
| IKBKG | -7367.0 |
| RAB3D | -7358.0 |
| CD52 | -7342.0 |
| LRRC41 | -7324.0 |
| DCTN2 | -7295.0 |
| STT3A | -7290.0 |
| PSME3 | -7280.0 |
| PSMB2 | -7268.0 |
| GALNT15 | -7260.0 |
| EDEM2 | -7195.0 |
| OS9 | -7193.0 |
| CDKN2A | -7189.0 |
| NUP62 | -7186.0 |
| CAPZB | -7174.0 |
| GFUS | -7164.0 |
| ADAMTSL2 | -7159.0 |
| F7 | -7142.0 |
| GGCX | -7137.0 |
| C4A | -7134.0 |
| CST3 | -7129.0 |
| DDA1 | -7113.0 |
| PSMD2 | -7104.0 |
| UBE2I | -7091.0 |
| RABGGTA | -7090.0 |
| TRIM27 | -7087.0 |
| PMM1 | -7072.0 |
| PDIA6 | -7070.0 |
| BABAM1 | -7037.0 |
| RAB11B | -7016.0 |
| APOE | -7009.0 |
| AAAS | -7005.0 |
| NR1H2 | -6960.0 |
| MGAT4B | -6946.0 |
| DCAF4 | -6938.0 |
| GALNT14 | -6930.0 |
| CTBP1 | -6915.0 |
| CCDC22 | -6893.0 |
| ADRM1 | -6891.0 |
| UBA52 | -6880.0 |
| PIGM | -6878.0 |
| INO80 | -6873.0 |
| TMED2 | -6853.0 |
| COPA | -6837.0 |
| ARRB2 | -6809.0 |
| MRTFA | -6807.0 |
| RHOA | -6754.0 |
| NUCB1 | -6738.0 |
| MAVS | -6723.0 |
| RANGAP1 | -6714.0 |
| CETN2 | -6713.0 |
| PSMB6 | -6709.0 |
| FUCA1 | -6706.0 |
| RAB5C | -6693.0 |
| DYNLL2 | -6690.0 |
| CALR | -6689.0 |
| DPAGT1 | -6669.0 |
| HSPA8 | -6665.0 |
| ARF5 | -6661.0 |
| RNF5 | -6648.0 |
| PSMB3 | -6647.0 |
| FBXW9 | -6624.0 |
| MVD | -6623.0 |
| RAB42 | -6608.0 |
| ELOB | -6600.0 |
| RRAGA | -6599.0 |
| SLC17A5 | -6589.0 |
| FBXO2 | -6574.0 |
| EIF5A | -6573.0 |
| RNF123 | -6560.0 |
| ARFGAP2 | -6556.0 |
| PARP1 | -6552.0 |
| COPG2 | -6550.0 |
| ADAMTS3 | -6521.0 |
| TRAPPC2L | -6498.0 |
| CDH2 | -6470.0 |
| DYNLL1 | -6465.0 |
| PSMD4 | -6452.0 |
| DERL1 | -6431.0 |
| NUP88 | -6417.0 |
| CSF1 | -6415.0 |
| TPGS1 | -6410.0 |
| RAB5B | -6400.0 |
| HGS | -6399.0 |
| MUC6 | -6359.0 |
| TAB1 | -6350.0 |
| ACTR1A | -6346.0 |
| PSMF1 | -6332.0 |
| LMAN2L | -6325.0 |
| SELENOS | -6312.0 |
| FBXL15 | -6290.0 |
| PARK7 | -6265.0 |
| RAB41 | -6262.0 |
| OTUD5 | -6256.0 |
| ALG2 | -6248.0 |
| POM121 | -6233.0 |
| H2BC12 | -6223.0 |
| TUBB4B | -6218.0 |
| COMMD5 | -6211.0 |
| GOSR2 | -6207.0 |
| TNIP1 | -6201.0 |
| UBB | -6193.0 |
| VDAC1 | -6184.0 |
| ST3GAL1 | -6158.0 |
| PIGF | -6157.0 |
| PIGV | -6155.0 |
| ENGASE | -6148.0 |
| PSMC5 | -6143.0 |
| RNF40 | -6134.0 |
| CHST8 | -6133.0 |
| NRN1L | -6115.0 |
| ADAMTS7 | -6113.0 |
| SEC24C | -6100.0 |
| PSMA7 | -6082.0 |
| SMAD3 | -6044.0 |
| TP53 | -6010.0 |
| NR1H3 | -5984.0 |
| USP20 | -5968.0 |
| RAB34 | -5960.0 |
| PSMB7 | -5953.0 |
| LGALS1 | -5938.0 |
| NAGK | -5927.0 |
| NAPA | -5914.0 |
| UBE2L3 | -5910.0 |
| RAB37 | -5902.0 |
| PSMC4 | -5866.0 |
| FBXO44 | -5864.0 |
| TPST1 | -5860.0 |
| RAB7A | -5854.0 |
| ANK1 | -5844.0 |
| FSTL1 | -5807.0 |
| USP4 | -5800.0 |
| SPSB4 | -5797.0 |
| ACTR8 | -5784.0 |
| ADAMTS16 | -5780.0 |
| RAB40B | -5779.0 |
| MAN1B1 | -5730.0 |
| PPARA | -5728.0 |
| PSMC3 | -5726.0 |
| UBE2F | -5708.0 |
| ARF4 | -5692.0 |
| MBTPS1 | -5686.0 |
| CHGB | -5684.0 |
| TRIM28 | -5673.0 |
| RAET1G | -5658.0 |
| SCG2 | -5652.0 |
| CP | -5647.0 |
| MDC1 | -5640.0 |
| SPSB2 | -5632.0 |
| BAP1 | -5598.0 |
| POMGNT1 | -5565.0 |
| GBF1 | -5553.0 |
| ASB8 | -5552.0 |
| INCENP | -5541.0 |
| RAB8A | -5535.0 |
| TMED10 | -5519.0 |
| VCP | -5509.0 |
| PSMB1 | -5473.0 |
| NOD2 | -5469.0 |
| RAB32 | -5463.0 |
| ARSG | -5459.0 |
| TRAPPC3 | -5420.0 |
| RAB7B | -5412.0 |
| USP11 | -5409.0 |
| MLEC | -5382.0 |
| TGOLN2 | -5360.0 |
| AXIN1 | -5355.0 |
| NUP93 | -5327.0 |
| PRKCSH | -5301.0 |
| PIGO | -5284.0 |
| FOLR1 | -5272.0 |
| DCAF7 | -5246.0 |
| APP | -5231.0 |
| PHC2 | -5219.0 |
| POMT2 | -5184.0 |
| CHST10 | -5170.0 |
| PSMB4 | -5168.0 |
| GALNT11 | -5160.0 |
| NUP37 | -5152.0 |
| ASB6 | -5125.0 |
| PEX2 | -5116.0 |
| FURIN | -5098.0 |
| COL7A1 | -5075.0 |
| ACTB | -5073.0 |
| DAXX | -5069.0 |
| SEC22B | -5055.0 |
| MPI | -5037.0 |
| KBTBD7 | -5035.0 |
| FBXL8 | -5033.0 |
| TRRAP | -5027.0 |
| PEX12 | -5023.0 |
| PTRH2 | -5005.0 |
| PREB | -4989.0 |
| WDR61 | -4919.0 |
| RAB40C | -4891.0 |
| CFP | -4887.0 |
| CBX5 | -4883.0 |
| UBE2Z | -4878.0 |
| PEX5 | -4860.0 |
| FBXO41 | -4858.0 |
| QSOX1 | -4847.0 |
| RNF185 | -4812.0 |
| KLHL41 | -4791.0 |
| ADAMTS10 | -4774.0 |
| SDC2 | -4765.0 |
| ZBTB16 | -4763.0 |
| NEU1 | -4756.0 |
| UBE2E3 | -4749.0 |
| NEU3 | -4741.0 |
| SKP1 | -4737.0 |
| LRR1 | -4728.0 |
| NUP188 | -4718.0 |
| VDAC2 | -4709.0 |
| AMDHD2 | -4690.0 |
| FUOM | -4679.0 |
| FBXL18 | -4675.0 |
| LY6E | -4670.0 |
| RING1 | -4669.0 |
| PSMD9 | -4655.0 |
| TPST2 | -4585.0 |
| NSMCE1 | -4581.0 |
| NRIP1 | -4579.0 |
| KDM1B | -4575.0 |
| HIPK2 | -4524.0 |
| NPL | -4519.0 |
| INO80E | -4502.0 |
| SHISA5 | -4501.0 |
| ANO8 | -4458.0 |
| RBX1 | -4435.0 |
| SEC31A | -4403.0 |
| DCTN6 | -4386.0 |
| TADA2B | -4382.0 |
| DYNC1H1 | -4355.0 |
| HSP90B1 | -4345.0 |
| TFG | -4337.0 |
| SEC22A | -4335.0 |
| COPB2 | -4312.0 |
| AGBL5 | -4299.0 |
| TRAF2 | -4296.0 |
| NSMCE3 | -4248.0 |
| IGFBP5 | -4220.0 |
| PLAUR | -4209.0 |
| THBS2 | -4197.0 |
| COG4 | -4189.0 |
| PSMC2 | -4179.0 |
| POMT1 | -4165.0 |
| TTLL11 | -4160.0 |
| SAR1B | -4109.0 |
| RELA | -4097.0 |
| PIGH | -4069.0 |
| IKBKE | -4068.0 |
| KLHL22 | -4065.0 |
| TBC1D20 | -4050.0 |
| FBXO27 | -4047.0 |
| FBXO7 | -4031.0 |
| PCNA | -3997.0 |
| DPM3 | -3983.0 |
| GALNT12 | -3979.0 |
| SEC22C | -3930.0 |
| AMTN | -3913.0 |
| FBXO9 | -3877.0 |
| PSMD10 | -3849.0 |
| POFUT2 | -3827.0 |
| VDR | -3798.0 |
| FAM20A | -3783.0 |
| TRAPPC9 | -3743.0 |
| CNTN4 | -3734.0 |
| MBD6 | -3726.0 |
| BTRC | -3694.0 |
| HLA-A | -3688.0 |
| NFRKB | -3680.0 |
| MAGT1 | -3673.0 |
| WFS1 | -3671.0 |
| COMMD7 | -3640.0 |
| UGGT1 | -3622.0 |
| CDC20 | -3613.0 |
| DPH7 | -3605.0 |
| NUP214 | -3603.0 |
| MGAT2 | -3597.0 |
| DHPS | -3587.0 |
| RTN4RL2 | -3585.0 |
| RNF7 | -3583.0 |
| YY1 | -3581.0 |
| B3GNTL1 | -3568.0 |
| LMAN1 | -3539.0 |
| TGFA | -3504.0 |
| USO1 | -3487.0 |
| USP30 | -3448.0 |
| COMMD4 | -3443.0 |
| ASB5 | -3435.0 |
| COMMD6 | -3420.0 |
| RUVBL1 | -3408.0 |
| H2BC5 | -3370.0 |
| TRAF3 | -3366.0 |
| ADAMTS2 | -3363.0 |
| CUL9 | -3329.0 |
| PIGW | -3280.0 |
| PIGU | -3244.0 |
| SPTB | -3234.0 |
| PSMA6 | -3225.0 |
| MAN2A2 | -3220.0 |
| COPS7B | -3219.0 |
| LAMB2 | -3202.0 |
| EDEM3 | -3174.0 |
| WSB2 | -3159.0 |
| GALNT6 | -3153.0 |
| CCNF | -3122.0 |
| PIGZ | -3115.0 |
| MGAT5 | -3110.0 |
| ARSI | -3079.0 |
| TNC | -3058.0 |
| RAE1 | -3056.0 |
| USP22 | -3053.0 |
| UBE2V2 | -3043.0 |
| PSME1 | -3031.0 |
| RNF20 | -3029.0 |
| PGM3 | -3025.0 |
| NUP98 | -3024.0 |
| RTF1 | -3000.0 |
| C1GALT1C1 | -2997.0 |
| ALG5 | -2985.0 |
| DOHH | -2983.0 |
| FBXO6 | -2980.0 |
| RAB44 | -2971.0 |
| TRIM4 | -2969.0 |
| FOXK2 | -2940.0 |
| FCSK | -2935.0 |
| BRCA1 | -2933.0 |
| CDC25A | -2926.0 |
| COMMD1 | -2902.0 |
| BECN1 | -2887.0 |
| MAN1A1 | -2863.0 |
| TRAPPC4 | -2838.0 |
| DPH3 | -2835.0 |
| CREBBP | -2822.0 |
| RFT1 | -2817.0 |
| SRD5A3 | -2797.0 |
| ZNF350 | -2778.0 |
| COPS3 | -2773.0 |
| DERL2 | -2770.0 |
| TFPT | -2767.0 |
| GALNT17 | -2742.0 |
| ARSB | -2736.0 |
| UBE2D2 | -2735.0 |
| PSMD7 | -2731.0 |
| ICMT | -2721.0 |
| FBXO4 | -2716.0 |
| MBD1 | -2706.0 |
| ACTR5 | -2705.0 |
| EEF2 | -2697.0 |
| WDR5 | -2673.0 |
| NSF | -2666.0 |
| PSMA5 | -2649.0 |
| HCFC1 | -2625.0 |
| APOL1 | -2619.0 |
| PSMC1 | -2604.0 |
| AR | -2536.0 |
| PIGK | -2511.0 |
| ARCN1 | -2503.0 |
| OTUB2 | -2489.0 |
| RAB20 | -2452.0 |
| ALG8 | -2436.0 |
| SPSB1 | -2411.0 |
| FBXW11 | -2408.0 |
| GALNT4 | -2395.0 |
| INO80B | -2375.0 |
| NEGR1 | -2357.0 |
| USP10 | -2330.0 |
| FBXO17 | -2307.0 |
| TUSC3 | -2306.0 |
| ADAMTS8 | -2265.0 |
| NUP85 | -2218.0 |
| HDAC4 | -2202.0 |
| RAB35 | -2190.0 |
| PIAS1 | -2173.0 |
| GALNT16 | -2172.0 |
| TNIP2 | -2170.0 |
| WDR20 | -2153.0 |
| OTOA | -2147.0 |
| PSMD14 | -2133.0 |
| ADAMTS6 | -2079.0 |
| CDCA8 | -2069.0 |
| ST8SIA4 | -2014.0 |
| SAE1 | -2006.0 |
| KLHL11 | -2004.0 |
| VCAN | -1970.0 |
| PEX14 | -1958.0 |
| TAF10 | -1955.0 |
| KBTBD6 | -1943.0 |
| COMMD8 | -1937.0 |
| FBXO40 | -1930.0 |
| RIPK1 | -1922.0 |
| NDC1 | -1920.0 |
| PIGG | -1917.0 |
| MXRA8 | -1894.0 |
| CASP8AP2 | -1860.0 |
| DCUN1D2 | -1817.0 |
| SUMO2 | -1786.0 |
| PSMD1 | -1782.0 |
| UBXN1 | -1779.0 |
| COG6 | -1764.0 |
| PSMA4 | -1756.0 |
| SPP1 | -1742.0 |
| XRCC4 | -1735.0 |
| TTLL4 | -1734.0 |
| GOLM1 | -1727.0 |
| GNPNAT1 | -1722.0 |
| CNIH1 | -1687.0 |
| ARRB1 | -1679.0 |
| HNRNPC | -1642.0 |
| CALU | -1638.0 |
| NUB1 | -1628.0 |
| DNAJC24 | -1627.0 |
| PIAS3 | -1615.0 |
| DNMT1 | -1609.0 |
| EEF1A1 | -1605.0 |
| PSME2 | -1591.0 |
| ALG9 | -1588.0 |
| ALG11 | -1573.0 |
| KLHL9 | -1561.0 |
| SATB2 | -1525.0 |
| RAB9B | -1509.0 |
| PSMD11 | -1483.0 |
| SPTAN1 | -1454.0 |
| VDAC3 | -1448.0 |
| PSMD5 | -1433.0 |
| MANEA | -1432.0 |
| COG2 | -1422.0 |
| OTUD7B | -1402.0 |
| TUBB3 | -1396.0 |
| TUBB6 | -1389.0 |
| HNRNPK | -1387.0 |
| RAB10 | -1385.0 |
| CISH | -1383.0 |
| MUC1 | -1357.0 |
| TOMM70 | -1316.0 |
| SAFB | -1313.0 |
| GMDS | -1304.0 |
| ZRANB1 | -1290.0 |
| PSMA2 | -1286.0 |
| RBBP5 | -1273.0 |
| RAD18 | -1265.0 |
| MDGA1 | -1262.0 |
| GFPT1 | -1256.0 |
| AURKA | -1234.0 |
| ADAMTS14 | -1232.0 |
| SIN3A | -1221.0 |
| COPS2 | -1211.0 |
| FBXW4 | -1204.0 |
| CCDC8 | -1190.0 |
| CTSC | -1185.0 |
| B4GALT4 | -1184.0 |
| ARSD | -1170.0 |
| FBN1 | -1168.0 |
| SEC24D | -1154.0 |
| PIAS4 | -1127.0 |
| THRA | -1081.0 |
| MUC12 | -1066.0 |
| ADAMTS13 | -1058.0 |
| OBSL1 | -1051.0 |
| SCMH1 | -1046.0 |
| COPS4 | -1031.0 |
| FBXL19 | -1026.0 |
| FBXO10 | -1005.0 |
| CHML | -983.0 |
| USP9X | -962.0 |
| CSNK1D | -956.0 |
| XPC | -942.0 |
| PTP4A2 | -940.0 |
| TTLL3 | -928.0 |
| USP2 | -897.0 |
| COPB1 | -893.0 |
| SPSB3 | -867.0 |
| FBXL5 | -865.0 |
| PROS1 | -863.0 |
| GOLGB1 | -831.0 |
| F8 | -828.0 |
| ZBED1 | -821.0 |
| ADAM10 | -804.0 |
| CDC34 | -803.0 |
| CAPZA2 | -802.0 |
| STS | -794.0 |
| PSMD13 | -754.0 |
| COG1 | -751.0 |
| ULBP2 | -743.0 |
| NUP205 | -738.0 |
| TTLL9 | -721.0 |
| AURKB | -685.0 |
| GORASP1 | -663.0 |
| B4GALT1 | -661.0 |
| NGLY1 | -653.0 |
| NUP42 | -641.0 |
| ADAMTS19 | -636.0 |
| F5 | -627.0 |
| RAB38 | -626.0 |
| DCAF6 | -606.0 |
| CDC73 | -598.0 |
| HDAC1 | -580.0 |
| RAB31 | -572.0 |
| PIGY | -555.5 |
| IGFBP3 | -549.0 |
| MTA1 | -545.0 |
| CANX | -540.0 |
| UBE2G2 | -536.0 |
| VWA1 | -525.0 |
| NUS1 | -501.0 |
| TFAP2C | -497.0 |
| UBE2R2 | -460.0 |
| UBE2K | -426.0 |
| RPS2 | -411.0 |
| NTNG2 | -408.0 |
| PPP6C | -407.0 |
| RAB27B | -396.0 |
| ACTR10 | -373.0 |
| SNX3 | -340.0 |
| SOCS6 | -332.0 |
| MAN1A2 | -330.0 |
| FBXO21 | -329.0 |
| TUBA1A | -304.0 |
| MAN2A1 | -288.0 |
| EP300 | -244.0 |
| PSMB8 | -235.0 |
| RAB2A | -220.0 |
| SVBP | -209.0 |
| STAM2 | -192.0 |
| COMMD2 | -183.0 |
| MFGE8 | -175.0 |
| NUP153 | -156.0 |
| SCFD1 | -136.0 |
| RCE1 | -125.0 |
| PRKDC | -116.0 |
| ALG10 | -89.0 |
| PIGC | -88.0 |
| TMED7 | -86.0 |
| STAMBP | -74.0 |
| PSME4 | -48.0 |
| RBBP7 | -26.0 |
| PSMD6 | 26.0 |
| CPM | 30.0 |
| RECK | 37.0 |
| DCTN4 | 48.0 |
| TRAPPC6A | 58.0 |
| LYPD3 | 93.0 |
| SEL1L | 121.0 |
| TRAPPC10 | 129.0 |
| PAF1 | 135.0 |
| NFKBIA | 181.0 |
| USP21 | 193.0 |
| H2AC6 | 204.0 |
| SPTBN5 | 209.0 |
| RPS27A | 229.0 |
| RAB9A | 231.0 |
| RAD23B | 243.0 |
| NICN1 | 253.0 |
| KCTD7 | 290.0 |
| SENP8 | 291.0 |
| UBE2G1 | 327.0 |
| FEM1A | 336.0 |
| USP16 | 341.0 |
| KBTBD8 | 348.0 |
| H2AW | 354.0 |
| FBXL13 | 359.0 |
| PSMA1 | 379.0 |
| ARFGAP3 | 381.0 |
| FEM1B | 396.0 |
| H2BU1 | 397.0 |
| TGFBR1 | 415.0 |
| OTULIN | 451.0 |
| CD109 | 455.0 |
| UBE2A | 466.0 |
| RAB40A | 478.0 |
| GOSR1 | 516.0 |
| TECTA | 537.0 |
| KTN1 | 539.0 |
| FOXK1 | 598.0 |
| MGAT4A | 612.0 |
| ART3 | 618.0 |
| GNE | 621.0 |
| VHL | 652.0 |
| USP37 | 673.0 |
| OGT | 674.0 |
| ESR1 | 690.0 |
| NAPG | 703.0 |
| COG7 | 714.0 |
| SMC1A | 733.0 |
| B3GNT8 | 739.0 |
| PIGN | 742.0 |
| ST3GAL4 | 774.0 |
| RAB4B | 790.0 |
| KLHL25 | 799.0 |
| RAB4A | 839.0 |
| RAB18 | 879.0 |
| DCAF8 | 886.0 |
| PML | 912.0 |
| ALG14 | 928.0 |
| SEC23A | 932.0 |
| RNF139 | 972.0 |
| LEO1 | 991.0 |
| OTUD7A | 1027.0 |
| COPS5 | 1035.0 |
| TTLL5 | 1043.0 |
| COMMD3 | 1045.0 |
| ST3GAL3 | 1150.0 |
| BST1 | 1165.0 |
| DDB2 | 1173.0 |
| XPNPEP2 | 1197.0 |
| ASXL2 | 1205.0 |
| TPGS2 | 1217.0 |
| SENP5 | 1269.0 |
| FBXL3 | 1274.0 |
| ADRB2 | 1284.0 |
| FBXL14 | 1285.0 |
| MAP3K7 | 1306.0 |
| ASB7 | 1320.0 |
| PIGP | 1336.0 |
| RAB29 | 1342.0 |
| ALPL | 1363.0 |
| DNAJC3 | 1382.0 |
| CUL1 | 1406.0 |
| TOMM20 | 1480.0 |
| YOD1 | 1509.0 |
| UBE2E1 | 1544.0 |
| RAB13 | 1575.0 |
| UBE2T | 1590.0 |
| MIA3 | 1620.0 |
| CMAS | 1623.0 |
| CALM1 | 1638.0 |
| RAB1A | 1661.0 |
| ACTL6A | 1675.0 |
| USP24 | 1681.0 |
| GALNT13 | 1700.0 |
| CCNA2 | 1702.0 |
| GALNT18 | 1728.0 |
| CAPZA1 | 1732.0 |
| UBE2N | 1734.0 |
| UBE2C | 1747.0 |
| FBXO22 | 1768.0 |
| STAG2 | 1773.0 |
| H2BC21 | 1774.0 |
| B4GALT5 | 1807.0 |
| FBXL12 | 1810.0 |
| APC | 1828.0 |
| DCAF10 | 1842.0 |
| RAB2B | 1849.0 |
| CHM | 1855.0 |
| EVA1A | 1857.0 |
| GALNT8 | 1860.0 |
| USP8 | 1874.0 |
| RAB14 | 1901.0 |
| DPM1 | 1909.0 |
| RAB24 | 1920.0 |
| FBXW2 | 1926.0 |
| RAB22A | 1939.0 |
| THRB | 1943.0 |
| TGFBR2 | 1948.0 |
| BMI1 | 1962.0 |
| RAB33B | 1966.0 |
| DCUN1D5 | 1976.0 |
| TP53BP1 | 1989.0 |
| COG5 | 1992.0 |
| DTL | 1996.0 |
| EID3 | 2028.0 |
| CUL4A | 2033.0 |
| NR3C1 | 2034.0 |
| RAB6A | 2072.0 |
| HIF3A | 2112.0 |
| NUP155 | 2114.0 |
| NUP35 | 2129.0 |
| MGAT4C | 2130.0 |
| UBE2B | 2133.0 |
| H2AC18 | 2134.0 |
| FPGT | 2142.0 |
| NUP54 | 2157.0 |
| SENP1 | 2163.0 |
| IGFBP4 | 2172.0 |
| FBXW8 | 2188.0 |
| VCPIP1 | 2192.0 |
| USP18 | 2206.0 |
| BTBD1 | 2212.0 |
| USP14 | 2217.0 |
| SMAD4 | 2253.0 |
| USP7 | 2256.0 |
| DPH5 | 2293.0 |
| SMURF2 | 2303.0 |
| RAB43 | 2319.0 |
| ASXL1 | 2331.0 |
| ASB15 | 2375.0 |
| RAD21 | 2392.0 |
| COPS8 | 2419.0 |
| NUP43 | 2453.0 |
| RAB39A | 2479.0 |
| CTR9 | 2482.0 |
| TOP2A | 2491.0 |
| FN3K | 2508.0 |
| SIAH2 | 2522.0 |
| TAF9B | 2561.0 |
| MAT2B | 2590.0 |
| TRIM13 | 2646.0 |
| DYNC1LI2 | 2656.0 |
| USP12 | 2665.0 |
| ASB16 | 2681.0 |
| NANP | 2777.0 |
| INO80C | 2780.0 |
| B3GLCT | 2794.0 |
| PIGB | 2795.0 |
| PIGL | 2806.0 |
| CYLD | 2838.0 |
| HERC2 | 2845.0 |
| FBXL4 | 2850.0 |
| IFIH1 | 2853.0 |
| WDR48 | 2906.0 |
| COMMD10 | 2920.0 |
| TTL | 2935.0 |
| SEC23IP | 2953.0 |
| C3 | 2977.0 |
| BLM | 2987.0 |
| GALNT1 | 3072.0 |
| KCTD6 | 3088.0 |
| TRAPPC2 | 3092.0 |
| SPON1 | 3126.0 |
| NTM | 3148.0 |
| WAC | 3155.0 |
| FBXO30 | 3156.0 |
| RANBP2 | 3171.0 |
| SLC35A1 | 3178.0 |
| DYNC1I2 | 3198.0 |
| USP34 | 3206.0 |
| KLHL20 | 3230.0 |
| STAG1 | 3239.0 |
| DPH1 | 3243.0 |
| UBC | 3246.0 |
| ELOC | 3260.0 |
| CUL5 | 3316.0 |
| CAMKMT | 3320.0 |
| KAT2A | 3322.0 |
| RAB23 | 3327.0 |
| UCHL5 | 3343.0 |
| KLHL13 | 3381.0 |
| GALNT7 | 3383.0 |
| PCGF2 | 3410.0 |
| UBA3 | 3420.0 |
| PUM2 | 3425.0 |
| SPON2 | 3448.0 |
| NCOA2 | 3470.0 |
| SEC24A | 3580.0 |
| EDEM1 | 3611.0 |
| AXIN2 | 3643.0 |
| PSMD12 | 3658.0 |
| NUP133 | 3662.0 |
| BIRC2 | 3674.0 |
| CUL2 | 3685.0 |
| SEC16B | 3690.0 |
| TNKS | 3694.0 |
| FOXO4 | 3729.0 |
| USP3 | 3738.0 |
| UBE2D3 | 3753.0 |
| MAN1C1 | 3794.0 |
| PSMC6 | 3801.0 |
| NUDT14 | 3804.0 |
| NLRP3 | 3857.0 |
| VASH1 | 3873.0 |
| ALG10B | 3876.0 |
| RWDD3 | 3879.0 |
| RAB6B | 3883.0 |
| COG3 | 3893.0 |
| NSMCE2 | 3902.0 |
| NCOA1 | 3941.0 |
| SEC24B | 3945.0 |
| SUZ12 | 3951.0 |
| SATB1 | 3955.0 |
| RNF2 | 3972.0 |
| SUMO1 | 3974.0 |
| DNMT3A | 3975.0 |
| TOP2B | 4017.0 |
| ASB2 | 4032.0 |
| KAT2B | 4056.0 |
| METTL22 | 4058.0 |
| CAND1 | 4089.0 |
| SENP2 | 4091.0 |
| DCAF5 | 4093.0 |
| RHOT1 | 4095.0 |
| UBE2Q2 | 4114.0 |
| PSMB9 | 4121.0 |
| ING2 | 4130.0 |
| GCNT1 | 4151.0 |
| RAB12 | 4152.0 |
| BRCC3 | 4165.0 |
| FBXO32 | 4176.0 |
| KLHL2 | 4179.0 |
| NAE1 | 4185.0 |
| DCAF13 | 4213.0 |
| SP3 | 4244.0 |
| GRIA1 | 4245.0 |
| RAB8B | 4281.0 |
| PIGX | 4282.0 |
| USP15 | 4285.0 |
| TNKS2 | 4320.0 |
| CHD3 | 4330.0 |
| ST3GAL5 | 4332.0 |
| SEH1L | 4352.0 |
| PHC1 | 4367.0 |
| UBA6 | 4398.0 |
| LSAMP | 4400.0 |
| FBXL20 | 4403.0 |
| USP28 | 4436.0 |
| DDX17 | 4440.0 |
| KIN | 4451.0 |
| SERPINA10 | 4458.0 |
| NUP58 | 4488.0 |
| NFKB2 | 4495.0 |
| PPARG | 4509.0 |
| ST6GAL1 | 4514.0 |
| MITF | 4532.0 |
| B3GNT4 | 4549.0 |
| ASB14 | 4566.0 |
| LAMC1 | 4580.0 |
| PEX13 | 4592.0 |
| CUL3 | 4595.0 |
| UBXN7 | 4609.0 |
| FBXL7 | 4619.0 |
| FBXW12 | 4698.0 |
| CBX4 | 4782.0 |
| SMC3 | 4789.0 |
| PRSS23 | 4797.0 |
| SHPRH | 4829.0 |
| HLA-B | 4836.0 |
| ST3GAL2 | 4843.0 |
| TRAPPC6B | 4845.0 |
| SPRN | 4851.0 |
| B3GNT7 | 4875.0 |
| MCFD2 | 4888.0 |
| B4GALT3 | 4889.0 |
| TOP1 | 4912.0 |
| UIMC1 | 4937.0 |
| ERCC8 | 4950.0 |
| ASB9 | 4957.0 |
| EIF5A2 | 5005.0 |
| B3GNT2 | 5007.0 |
| PGR | 5027.0 |
| RABGGTB | 5039.0 |
| SPTBN1 | 5040.0 |
| HRC | 5041.0 |
| ETFBKMT | 5047.0 |
| PSMA3 | 5077.0 |
| DCUN1D1 | 5093.0 |
| CHRDL1 | 5113.0 |
| RNF103 | 5131.0 |
| STAM | 5156.0 |
| USP47 | 5189.0 |
| NUP160 | 5248.0 |
| ALG13 | 5249.0 |
| SUDS3 | 5287.0 |
| HDAC7 | 5297.0 |
| RAB27A | 5323.0 |
| UBE2H | 5344.0 |
| AGBL3 | 5356.0 |
| SMC6 | 5366.0 |
| USP42 | 5369.0 |
| MDM2 | 5371.0 |
| SEM1 | 5372.0 |
| HLTF | 5377.0 |
| UBE2S | 5380.0 |
| ASGR2 | 5395.0 |
| UBE2D1 | 5427.0 |
| FBXO11 | 5446.0 |
| ATXN3 | 5486.0 |
| RAB5A | 5503.0 |
| MBD5 | 5525.0 |
| PPP6R3 | 5531.0 |
| RAB3A | 5550.0 |
| GAS6 | 5559.0 |
| ST6GAL2 | 5571.0 |
| UBA2 | 5577.0 |
| RAB15 | 5595.0 |
| NPM1 | 5611.0 |
| ST8SIA5 | 5624.0 |
| SPTBN2 | 5752.0 |
| NUP50 | 5758.0 |
| BGLAP | 5805.0 |
| INO80D | 5850.0 |
| PGAP1 | 5851.0 |
| CBX2 | 5858.0 |
| GALNT3 | 5872.0 |
| BARD1 | 5883.0 |
| SMAD2 | 5913.0 |
| TULP4 | 5934.0 |
| PRMT3 | 5939.0 |
| SMC5 | 5946.0 |
| DCAF17 | 5949.0 |
| CD59 | 6004.0 |
| UGGT2 | 6005.0 |
| BIRC3 | 6018.0 |
| B3GNT3 | 6092.0 |
| PIAS2 | 6094.0 |
| WRN | 6108.0 |
| NOP58 | 6115.0 |
| PHC3 | 6121.0 |
| MGAT3 | 6122.0 |
| GCNT3 | 6123.0 |
| HDAC2 | 6141.0 |
| RAB21 | 6148.0 |
| DCAF16 | 6173.0 |
| RNF146 | 6176.0 |
| ARSK | 6184.0 |
| LYPD5 | 6212.0 |
| USP33 | 6231.0 |
| LARGE1 | 6267.0 |
| DYNC1LI1 | 6270.0 |
| ASGR1 | 6280.0 |
| MARCHF6 | 6307.0 |
| USP48 | 6318.0 |
| SOCS5 | 6321.0 |
| NSMCE4A | 6327.0 |
| TMEM132A | 6336.0 |
| RAD52 | 6357.0 |
| ARSJ | 6373.0 |
| B4GALNT2 | 6425.0 |
| TOPORS | 6434.0 |
| FBXW7 | 6440.0 |
| CCP110 | 6457.0 |
| METTL21A | 6498.0 |
| FSTL3 | 6522.0 |
| RARA | 6535.0 |
| PPARGC1A | 6593.0 |
| NOD1 | 6632.0 |
| FBXO31 | 6642.0 |
| LAMB1 | 6643.0 |
| IDE | 6644.0 |
| USP25 | 6658.0 |
| MIA2 | 6675.0 |
| KLHL5 | 6693.0 |
| GAN | 6694.0 |
| RAB11A | 6758.0 |
| CDK1 | 6780.0 |
| RORA | 6791.0 |
| THSD7A | 6817.0 |
| OTUD3 | 6875.0 |
| CNIH3 | 6900.0 |
| BET1 | 6923.0 |
| ATXN7 | 6942.0 |
| TRIM25 | 6947.0 |
| TDG | 6968.0 |
| VNN1 | 6989.0 |
| LYPD1 | 7000.0 |
| PTEN | 7006.0 |
| NR3C2 | 7022.0 |
| NAPB | 7024.0 |
| RAB3C | 7033.0 |
| ANKRD28 | 7067.0 |
| CUL4B | 7088.0 |
| LRRC49 | 7126.0 |
| LMO7 | 7131.0 |
| TNIP3 | 7133.0 |
| GATA3 | 7139.0 |
| POLB | 7155.0 |
| ASB3 | 7208.0 |
| SPARCL1 | 7231.0 |
| TRAF6 | 7237.0 |
| HIF1A | 7278.0 |
| UBE2W | 7287.0 |
| TUBB1 | 7292.0 |
| JOSD1 | 7301.0 |
| RCN1 | 7303.0 |
| SP100 | 7340.0 |
| ANK2 | 7369.0 |
| GPIHBP1 | 7380.0 |
| DCUN1D3 | 7393.0 |
| TTLL7 | 7420.0 |
| KLHL42 | 7422.0 |
| RAB30 | 7434.0 |
| KLHL21 | 7460.0 |
| FUT8 | 7476.0 |
| MYSM1 | 7546.0 |
| ZNF131 | 7600.0 |
| RNF168 | 7636.0 |
| DPH6 | 7659.0 |
| DYNC1I1 | 7687.0 |
| RAB3B | 7729.0 |
| DDX58 | 7734.0 |
| TUBB2B | 7803.0 |
| B4GALT6 | 7825.0 |
| B3GALNT2 | 7827.0 |
| THSD1 | 7840.0 |
| TUBB2A | 7849.0 |
| ASB4 | 7855.0 |
| ST6GALNAC1 | 7860.0 |
| SKP2 | 7870.0 |
| DNMT3B | 7873.0 |
| STX17 | 7909.0 |
| MYC | 7937.0 |
| AREG | 7970.0 |
| USP49 | 7998.0 |
| ADAMTS12 | 8006.0 |
| TNFAIP3 | 8015.0 |
| CBX8 | 8025.0 |
| DDX5 | 8105.0 |
| RAB17 | 8106.0 |
| ANKRD9 | 8112.0 |
| MDM4 | 8113.0 |
| TF | 8137.0 |
| AGBL2 | 8150.0 |
| ST8SIA1 | 8155.0 |
| EPAS1 | 8247.0 |
| THY1 | 8270.0 |
| BCL10 | 8277.0 |
| STAMBPL1 | 8314.0 |
| VASH2 | 8373.0 |
| FBXL22 | 8385.0 |
| VCPKMT | 8388.0 |
| SSPOP | 8392.0 |
| GPC3 | 8446.0 |
| POMK | 8570.0 |
| AGTPBP1 | 8608.0 |
| GPLD1 | 8648.0 |
| ST3GAL6 | 8762.0 |
| DCUN1D4 | 8786.0 |
| MATN3 | 8811.0 |
| NR2C1 | 8813.0 |
| FGF23 | 8821.0 |
| ALG6 | 8828.0 |
| F10 | 8831.0 |
| USP13 | 8835.0 |
| BIRC5 | 8840.0 |
| ST6GALNAC2 | 8874.0 |
| NRN1 | 8915.0 |
| FEM1C | 8932.0 |
| RIPK2 | 8936.0 |
| SMAD7 | 8944.0 |
| NTNG1 | 8947.0 |
| B3GNT5 | 8990.0 |
| RNF144A | 9021.0 |
| ST6GALNAC3 | 9031.0 |
| NUP107 | 9235.0 |
| SPTA1 | 9241.0 |
| SOCS2 | 9251.0 |
| FBXO15 | 9320.0 |
| CLSPN | 9486.0 |
| HIC1 | 9512.0 |
| WSB1 | 9620.0 |
| MUC3A | 9677.0 |
| ADAMTS1 | 9694.0 |
| IGFBP7 | 9699.0 |
| PIGA | 9708.0 |
| NR5A2 | 9715.0 |
| IL33 | 9720.0 |
| ST8SIA6 | 9759.0 |
| KLHL3 | 9836.0 |
| IL6 | 9872.0 |
| UHRF2 | 9931.0 |
| VNN2 | 9938.0 |
| ADAMTSL1 | 9951.0 |
| ART4 | 9955.0 |
| ADAMTS4 | 9961.0 |
| STC2 | 9978.0 |
| NR4A2 | 9993.0 |
| GCNT4 | 10004.0 |
| SOCS3 | 10041.0 |
| SEMA5B | 10059.0 |
| ADAMTS18 | 10060.0 |
| THBS1 | 10064.0 |
| RNF152 | 10082.0 |
| SMAD1 | 10096.0 |
| ADAMTS9 | 10114.0 |
| FCGR3B | 10145.0 |
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
| 544 | |
|---|---|
| set | Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| setSize | 140 |
| pANOVA | 3.89e-17 |
| s.dist | -0.412 |
| p.adjustANOVA | 1.71e-15 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| SIGLEC7 | -9100 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| SIGLEC7 | -9100 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| SLAMF7 | -8988 |
| IGHV1-2 | -8953 |
| LILRA2 | -8939 |
| OSCAR | -8923 |
| IGHV1-46 | -8910 |
| IGKV2D-28 | -8875 |
| IGKV3-11 | -8864 |
| CD81 | -8856 |
| IGKV1D-39 | -8828 |
| IGLV3-21 | -8806 |
| CD99 | -8784 |
| CLEC4G | -8780 |
| IGLV3-25 | -8773 |
| TREML1 | -8715 |
| ITGB2 | -8620 |
| IGHV3-33 | -8608 |
| IGLV2-14 | -8572 |
| ITGB7 | -8556 |
| LAIR1 | -8472 |
| TREM1 | -8429 |
| PILRA | -8421 |
| SIGLEC1 | -8398 |
| MADCAM1 | -8397 |
| LILRB2 | -8379 |
| TYROBP | -8356 |
| CD8B | -8225 |
| SLAMF6 | -8138 |
| IGLV1-40 | -8088 |
| SIGLEC5 | -8058 |
| FCGR3A | -8055 |
| LILRB3 | -8035 |
| LILRB4 | -7957 |
| CD300A | -7613 |
| LILRB5 | -7407 |
| IGKV3-15 | -7403 |
| TREM2 | -7286 |
| LILRA6 | -7161 |
| IGHV3-11 | -7017 |
| SIGLEC9 | -7013 |
| PIANP | -6992 |
| SIGLEC11 | -6957 |
| CD33 | -6926 |
| VCAM1 | -6799 |
| CD300C | -6768 |
| SIGLEC6 | -6204 |
| TRBC1 | -6095 |
| SIGLEC8 | -6076 |
| LILRB1 | -5584 |
| ICAM5 | -5497 |
| CD3E | -5364 |
| RAET1E | -5308 |
| COLEC12 | -5183 |
| CD22 | -4929 |
| TRAC | -4873 |
| CD8A | -4727 |
| IGKV1-33 | -4702 |
| FCGR2B | -4271 |
| CD300LF | -4120 |
| HLA-A | -3688 |
| CD96 | -3514 |
| SIGLEC10 | -3480 |
| CD19 | -3284 |
| ITGA4 | -3150 |
| FCGR1A | -2944 |
| CD3D | -2603 |
| KLRB1 | -2458 |
| CD40 | -2074 |
| HCST | -2012 |
| B2M | -1976 |
| LILRA5 | -1773 |
| NCR3LG1 | -1489 |
| CD247 | -834 |
| HLA-H | -815 |
| SH2D1A | -253 |
| CD300LB | -68 |
| CXADR | 117 |
| CD226 | 648 |
| CD200R1 | 1185 |
| KLRG1 | 1337 |
| ICAM3 | 1443 |
| ICAM2 | 1582 |
| ITGAL | 1798 |
| LILRA1 | 2083 |
| CLEC2D | 2089 |
| CD300E | 2454 |
| PVR | 2719 |
| C3 | 2977 |
| IFITM1 | 2988 |
| CD40LG | 3313 |
| PILRB | 3491 |
| CD3G | 4272 |
| ITGB1 | 4542 |
| HLA-E | 4804 |
| CD1C | 4814 |
| HLA-B | 4836 |
| KLRK1 | 5011 |
| HLA-F | 5232 |
| SELL | 5962 |
| CD1D | 6125 |
| MICA | 6191 |
| CRTAM | 6467 |
| ULBP3 | 6532 |
| NECTIN2 | 6697 |
| ICAM1 | 6879 |
| MICB | 6901 |
| CD34 | 7230 |
| KLRD1 | 7367 |
| JAML | 7421 |
| HLA-C | 7759 |
| TREML2 | 7872 |
| CD160 | 7878 |
| CD300LG | 7880 |
| CDH1 | 8078 |
| CLEC2B | 8571 |
| NPDC1 | 8705 |
| CD200 | 10146 |
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
| 1066 | |
|---|---|
| set | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| setSize | 125 |
| pANOVA | 8.3e-17 |
| s.dist | -0.431 |
| p.adjustANOVA | 3.54e-15 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SURF1 | -8554 |
| NDUFAF3 | -8511 |
| NDUFA11 | -8504 |
| CYC1 | -8353 |
| COX8A | -8260 |
| TACO1 | -8234 |
| ATP5MF | -8232 |
| ATP5F1D | -8212 |
| ETFB | -8156 |
| UQCRC1 | -7995 |
| NDUFA13 | -7854 |
| NDUFB10 | -7825 |
| NDUFS7 | -7728 |
| UQCR10 | -7703 |
| NDUFB7 | -7699 |
| NDUFS8 | -7687 |
| SDHA | -7652 |
| NDUFC1 | -7608 |
| ATP5ME | -7594 |
| NDUFA1 | -7540 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SURF1 | -8554 |
| NDUFAF3 | -8511 |
| NDUFA11 | -8504 |
| CYC1 | -8353 |
| COX8A | -8260 |
| TACO1 | -8234 |
| ATP5MF | -8232 |
| ATP5F1D | -8212 |
| ETFB | -8156 |
| UQCRC1 | -7995 |
| NDUFA13 | -7854 |
| NDUFB10 | -7825 |
| NDUFS7 | -7728 |
| UQCR10 | -7703 |
| NDUFB7 | -7699 |
| NDUFS8 | -7687 |
| SDHA | -7652 |
| NDUFC1 | -7608 |
| ATP5ME | -7594 |
| NDUFA1 | -7540 |
| UQCRFS1 | -7522 |
| COX6B1 | -7448 |
| NDUFA6 | -7341 |
| ATP5MC1 | -7251 |
| COX6A1 | -7180 |
| NDUFC2 | -7108 |
| UQCR11 | -6919 |
| ATP5MC3 | -6841 |
| COX5B | -6747 |
| COX5A | -6735 |
| NDUFA3 | -6716 |
| SDHC | -6686 |
| NDUFA4 | -6655 |
| NDUFA8 | -6633 |
| ATP5MC2 | -6628 |
| NDUFS5 | -6581 |
| MT-ND6 | -6516 |
| ATP5F1E | -6502 |
| NDUFB11 | -6495 |
| COX7B | -6445 |
| NDUFV3 | -6428 |
| SDHB | -6352 |
| UCP2 | -6186 |
| NDUFB4 | -6053 |
| UQCRQ | -6043 |
| NDUFA2 | -6040 |
| NDUFB2 | -5967 |
| NDUFS3 | -5954 |
| ATP5F1A | -5919 |
| NDUFAB1 | -5886 |
| MT-ND5 | -5735 |
| NDUFB3 | -5630 |
| ATP5PD | -5586 |
| NDUFB8 | -5569 |
| ATP5PF | -5543 |
| NDUFS6 | -5537 |
| NDUFAF4 | -5432 |
| COX7C | -5326 |
| SCO1 | -5322 |
| COX4I1 | -5248 |
| ATP5F1B | -5140 |
| NDUFB9 | -5052 |
| SCO2 | -4979 |
| COX19 | -4867 |
| COX16 | -4673 |
| COX14 | -4545 |
| ATP5MG | -4489 |
| ATP5PB | -4467 |
| ECSIT | -4451 |
| NDUFV1 | -4257 |
| COX6C | -4240 |
| ATP5PO | -4216 |
| TMEM186 | -4208 |
| NDUFS4 | -4157 |
| NDUFAF1 | -4070 |
| TIMMDC1 | -4054 |
| NDUFB1 | -4014 |
| NDUFV2 | -3987 |
| MT-ATP8 | -3771 |
| ACAD9 | -3714 |
| NDUFA7 | -3704 |
| COX11 | -3330 |
| TRAP1 | -3119 |
| ATP5F1C | -3076 |
| NDUFB6 | -2896 |
| NDUFAF2 | -2788 |
| UQCRH | -2661 |
| NUBPL | -2171 |
| COQ10A | -1825 |
| COX7A2L | -1534 |
| NDUFAF6 | -1480 |
| ETFA | -1469 |
| NDUFA5 | -1323 |
| UCP3 | -1280 |
| NDUFA12 | -1250 |
| MT-CO3 | -1115 |
| COX18 | -1013 |
| MT-CO2 | -988 |
| NDUFB5 | -429 |
| NDUFS1 | -297 |
| MT-ND4 | -94 |
| DMAC2L | -25 |
| MT-ND2 | 425 |
| UQCRC2 | 468 |
| MT-CO1 | 720 |
| MT-ATP6 | 1105 |
| UQCRB | 1227 |
| NDUFAF7 | 1789 |
| COA1 | 1872 |
| MT-ND3 | 1944 |
| TMEM126B | 2158 |
| SDHD | 3003 |
| ETFDH | 3008 |
| NDUFS2 | 3010 |
| SLC25A14 | 3046 |
| NDUFA9 | 3450 |
| NDUFA10 | 3483 |
| MT-ND1 | 3710 |
| LRPPRC | 4418 |
| MT-CYB | 5619 |
| CYCS | 7385 |
| NDUFAF5 | 7395 |
| COQ10B | 7585 |
| COX20 | 7745 |
| SLC25A27 | 8962 |
FCGR3A-mediated IL10 synthesis
| 384 | |
|---|---|
| set | FCGR3A-mediated IL10 synthesis |
| setSize | 77 |
| pANOVA | 1.36e-16 |
| s.dist | -0.545 |
| p.adjustANOVA | 5.63e-15 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGHG2 | -9159 |
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHG3 | -9150 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHG1 | -9102 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| IGHV1-2 | -8953 |
| IGHV1-46 | -8910 |
| IGKV2D-28 | -8875 |
| IGHG4 | -8874 |
| IGKV3-11 | -8864 |
| IGKV1D-39 | -8828 |
| FGR | -8811 |
| IGLV3-21 | -8806 |
| IGLV3-25 | -8773 |
| IGHV3-33 | -8608 |
| IGLV2-14 | -8572 |
| PRKACA | -8490 |
| HCK | -8242 |
| SRC | -8148 |
| IGLV1-40 | -8088 |
| FCGR3A | -8055 |
| IGKV3-15 | -7403 |
| IGHV3-11 | -7017 |
| SYK | -6217 |
| ADCY8 | -6200 |
| ADCY1 | -5762 |
| ADCY9 | -5551 |
| ITPR3 | -5506 |
| FYN | -4854 |
| FCGR2A | -4754 |
| IGKV1-33 | -4702 |
| PRKACB | -3946 |
| FCGR1A | -2944 |
| LYN | -2889 |
| ADCY7 | -1010 |
| CD247 | -834 |
| PRKAR1B | -805 |
| AHCYL1 | -485 |
| PRKAR2A | -154 |
| ADCY6 | 1400 |
| PRKAR2B | 1526 |
| CALM1 | 1638 |
| PRKX | 2487 |
| PRKAR1A | 3280 |
| CREB1 | 3370 |
| ADCY2 | 3878 |
| ADCY5 | 4004 |
| ITPR2 | 4036 |
| CD3G | 4272 |
| ADCY3 | 5125 |
| IL10 | 5196 |
| PLCG1 | 5830 |
| YES1 | 6926 |
| PLCG2 | 8985 |
| ADCY4 | 9424 |
| ITPR1 | 9487 |
Metabolism of carbohydrates
| 668 | |
|---|---|
| set | Metabolism of carbohydrates |
| setSize | 265 |
| pANOVA | 4.56e-16 |
| s.dist | -0.29 |
| p.adjustANOVA | 1.84e-14 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| FBP1 | -8962 |
| GAA | -8936 |
| CHPF2 | -8912 |
| PC | -8891 |
| FMOD | -8843 |
| CHST12 | -8810 |
| SLC35B2 | -8753 |
| GAPDH | -8745 |
| FUT4 | -8736 |
| NUP210 | -8727 |
| MAN2B2 | -8700 |
| ST6GALNAC6 | -8684 |
| KERA | -8680 |
| CHPF | -8666 |
| SEC13 | -8653 |
| HK3 | -8652 |
| PCK2 | -8648 |
| ALDOA | -8627 |
| NHLRC1 | -8617 |
| B4GAT1 | -8568 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| FBP1 | -8962 |
| GAA | -8936 |
| CHPF2 | -8912 |
| PC | -8891 |
| FMOD | -8843 |
| CHST12 | -8810 |
| SLC35B2 | -8753 |
| GAPDH | -8745 |
| FUT4 | -8736 |
| NUP210 | -8727 |
| MAN2B2 | -8700 |
| ST6GALNAC6 | -8684 |
| KERA | -8680 |
| CHPF | -8666 |
| SEC13 | -8653 |
| HK3 | -8652 |
| PCK2 | -8648 |
| ALDOA | -8627 |
| NHLRC1 | -8617 |
| B4GAT1 | -8568 |
| G6PC3 | -8561 |
| HS6ST1 | -8558 |
| MAN2B1 | -8524 |
| SDC3 | -8509 |
| PRKACA | -8490 |
| NDST2 | -8423 |
| HYAL1 | -8407 |
| CEMIP | -8376 |
| SLC37A2 | -8373 |
| HS3ST2 | -8351 |
| GALK1 | -8324 |
| B4GALT2 | -8317 |
| MDH2 | -8286 |
| SLC25A11 | -8254 |
| UST | -8230 |
| PFKP | -8214 |
| SLC9A1 | -8195 |
| CHST2 | -8190 |
| GLB1 | -8189 |
| G6PD | -8168 |
| ALDOC | -8085 |
| PRELP | -8076 |
| PGD | -8046 |
| ENO1 | -8009 |
| BGN | -7906 |
| POM121C | -7894 |
| AKR1A1 | -7793 |
| ENO3 | -7787 |
| TPR | -7773 |
| B3GALT6 | -7746 |
| SGSH | -7668 |
| GPC6 | -7588 |
| HK1 | -7518 |
| PKM | -7496 |
| GUSB | -7411 |
| CRYL1 | -7320 |
| SLC25A1 | -7210 |
| NUP62 | -7186 |
| B3GAT3 | -7173 |
| PGM1 | -7071 |
| HS3ST3A1 | -7047 |
| PFKL | -7021 |
| TALDO1 | -7011 |
| AAAS | -7005 |
| CSPG4 | -7003 |
| KHK | -6980 |
| PPP2R1A | -6964 |
| UBA52 | -6880 |
| GPC5 | -6778 |
| PGLS | -6775 |
| EXT2 | -6767 |
| HEXA | -6728 |
| PGAM2 | -6710 |
| PYGB | -6678 |
| B3GALT4 | -6432 |
| NUP88 | -6417 |
| TPI1 | -6372 |
| PYGM | -6261 |
| GPI | -6235 |
| POM121 | -6233 |
| B4GALT7 | -6219 |
| UBB | -6193 |
| ST3GAL1 | -6158 |
| XYLT1 | -6073 |
| GOT1 | -6071 |
| NAGLU | -6035 |
| ALDH1A1 | -6011 |
| PGAM1 | -6006 |
| PGK1 | -5872 |
| CHST13 | -5834 |
| PPP2R5D | -5791 |
| AKR1B1 | -5682 |
| RHCE | -5618 |
| SDC1 | -5597 |
| GNPDA1 | -5594 |
| CHST14 | -5507 |
| ADPGK | -5464 |
| GYS1 | -5458 |
| HEXB | -5455 |
| PHKG1 | -5399 |
| NUP93 | -5327 |
| CHP1 | -5319 |
| CD44 | -5281 |
| GALE | -5230 |
| IDUA | -5179 |
| GOT2 | -5177 |
| B3GALT1 | -5165 |
| NUP37 | -5152 |
| GLB1L | -4843 |
| GNS | -4788 |
| CHST11 | -4784 |
| SDC2 | -4765 |
| PRPS1 | -4720 |
| NUP188 | -4718 |
| PGP | -4717 |
| SLC26A2 | -4703 |
| HS3ST3B1 | -4626 |
| HYAL3 | -4388 |
| HAS2 | -4369 |
| PAPSS2 | -4292 |
| PAPSS1 | -4246 |
| TKT | -4075 |
| GYG1 | -3994 |
| PRKACB | -3946 |
| MANBA | -3901 |
| SLC37A4 | -3875 |
| TKFC | -3846 |
| PHKG2 | -3837 |
| CHST3 | -3720 |
| SDC4 | -3718 |
| EXT1 | -3644 |
| NUP214 | -3603 |
| GBE1 | -3532 |
| LYVE1 | -3078 |
| RAE1 | -3056 |
| NUP98 | -3024 |
| MDH1 | -2962 |
| XYLB | -2915 |
| OGN | -2906 |
| UGP2 | -2885 |
| PFKFB1 | -2806 |
| ARSB | -2736 |
| RHD | -2718 |
| AGL | -2689 |
| HS6ST3 | -2413 |
| DCXR | -2407 |
| PPP2CB | -2329 |
| SHPK | -2304 |
| NUP85 | -2218 |
| HS2ST1 | -2178 |
| XYLT2 | -2174 |
| AGRN | -2113 |
| FUT11 | -2104 |
| HAS3 | -1971 |
| VCAN | -1970 |
| NDC1 | -1920 |
| DSEL | -1896 |
| HPSE | -1810 |
| PHKA2 | -1809 |
| SLC2A1 | -1743 |
| LUM | -1737 |
| FUT10 | -1693 |
| BPGM | -1653 |
| SLC26A1 | -1543 |
| CHST15 | -1492 |
| PHKA1 | -1399 |
| GNPDA2 | -1252 |
| B4GALT4 | -1184 |
| HS3ST1 | -933 |
| GCKR | -862 |
| CHST6 | -856 |
| ACAN | -799 |
| FUT7 | -742 |
| NUP205 | -738 |
| SLC25A10 | -722 |
| B4GALT1 | -661 |
| NUP42 | -641 |
| ABCC5 | -621 |
| HPSE2 | -564 |
| HYAL2 | -264 |
| DSE | -254 |
| NUP153 | -156 |
| FBP2 | -135 |
| PYGL | 29 |
| SLC25A12 | 133 |
| RPS27A | 229 |
| MAN2C1 | 476 |
| DCN | 553 |
| GPC1 | 659 |
| ST3GAL4 | 774 |
| HSPG2 | 885 |
| GYG2 | 916 |
| GALT | 941 |
| DERA | 944 |
| ST3GAL3 | 1150 |
| IDS | 1175 |
| SORD | 1625 |
| CALM1 | 1638 |
| B4GALT5 | 1807 |
| PRPS2 | 1942 |
| EPM2A | 2084 |
| NUP155 | 2114 |
| NUP35 | 2129 |
| GLCE | 2143 |
| NUP54 | 2157 |
| NUP43 | 2453 |
| RPE | 2477 |
| SLC35B3 | 2700 |
| PFKM | 2765 |
| HMMR | 2793 |
| GPC4 | 3048 |
| RANBP2 | 3171 |
| UBC | 3246 |
| GLYCTK | 3508 |
| PPP2CA | 3519 |
| PFKFB4 | 3630 |
| NUP133 | 3662 |
| PFKFB2 | 3768 |
| SLC37A1 | 3929 |
| PHKB | 4007 |
| GCK | 4205 |
| SEH1L | 4352 |
| PPP1R3C | 4413 |
| NUP58 | 4488 |
| B3GNT4 | 4549 |
| RPIA | 4687 |
| ST3GAL2 | 4843 |
| OMD | 4868 |
| B3GNT7 | 4875 |
| B4GALT3 | 4889 |
| B3GNT2 | 5007 |
| FUT2 | 5016 |
| NUP160 | 5248 |
| CSGALNACT1 | 5250 |
| GPC2 | 5376 |
| ENO2 | 5690 |
| PGM2 | 5693 |
| NUP50 | 5758 |
| HK2 | 5854 |
| SLC35D2 | 5919 |
| B3GNT3 | 6092 |
| B4GALNT2 | 6425 |
| CHST7 | 6768 |
| RBKS | 6856 |
| PGM2L1 | 7240 |
| NDST1 | 7485 |
| B3GAT2 | 7557 |
| B3GAT1 | 7740 |
| HAS1 | 7776 |
| B4GALT6 | 7825 |
| CSGALNACT2 | 7871 |
| CHST1 | 8070 |
| CHSY3 | 8190 |
| CHSY1 | 8230 |
| GPC3 | 8446 |
| PPP2R1B | 8460 |
| PCK1 | 8565 |
| CHST5 | 8759 |
| ST3GAL6 | 8762 |
| STAB2 | 8771 |
| SLC25A13 | 8791 |
| NUP107 | 9235 |
| FUT1 | 9802 |
| ABO | 9847 |
| PFKFB3 | 10116 |
Mitochondrial translation elongation
| 698 | |
|---|---|
| set | Mitochondrial translation elongation |
| setSize | 90 |
| pANOVA | 1.66e-15 |
| s.dist | -0.485 |
| p.adjustANOVA | 6.51e-14 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| MRPS6 | -8791 |
| MRPL38 | -8772 |
| MRPS34 | -8726 |
| ERAL1 | -8635 |
| MRPS24 | -8489 |
| MRPL57 | -8452 |
| MRPL41 | -8451 |
| MRPL4 | -8434 |
| MRPL12 | -8422 |
| AURKAIP1 | -8335 |
| TSFM | -8273 |
| MRPL10 | -8223 |
| MRPL34 | -8071 |
| MRPL43 | -8060 |
| MRPL2 | -8039 |
| MRPL16 | -7965 |
| MRPS16 | -7777 |
| MRPL20 | -7416 |
| MRPL23 | -7387 |
| MRPS18A | -7353 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MRPS6 | -8791 |
| MRPL38 | -8772 |
| MRPS34 | -8726 |
| ERAL1 | -8635 |
| MRPS24 | -8489 |
| MRPL57 | -8452 |
| MRPL41 | -8451 |
| MRPL4 | -8434 |
| MRPL12 | -8422 |
| AURKAIP1 | -8335 |
| TSFM | -8273 |
| MRPL10 | -8223 |
| MRPL34 | -8071 |
| MRPL43 | -8060 |
| MRPL2 | -8039 |
| MRPL16 | -7965 |
| MRPS16 | -7777 |
| MRPL20 | -7416 |
| MRPL23 | -7387 |
| MRPS18A | -7353 |
| MRPS7 | -7107 |
| MRPS11 | -7057 |
| MRPS18B | -7020 |
| MRPL14 | -6937 |
| MRPS12 | -6931 |
| MRPL49 | -6736 |
| MRPL40 | -6680 |
| MRPL54 | -6656 |
| MRPL22 | -6642 |
| CHCHD1 | -6474 |
| MRPS2 | -6344 |
| MRPL55 | -6245 |
| MRPL53 | -6232 |
| TUFM | -6084 |
| MRPL24 | -6045 |
| MRPL17 | -6025 |
| GADD45GIP1 | -6013 |
| MRPL9 | -5907 |
| MRPL27 | -5620 |
| MRPS23 | -5587 |
| MRPS17 | -5568 |
| MRPL46 | -5557 |
| MRPL37 | -5406 |
| MRPL28 | -5240 |
| MRPL3 | -5226 |
| MRPL36 | -4842 |
| MRPS22 | -4795 |
| MRPL13 | -4750 |
| MRPS27 | -4548 |
| MRPL15 | -4532 |
| MRPS21 | -4522 |
| MRPS10 | -4427 |
| MRPL47 | -4298 |
| MRPL44 | -4200 |
| MRPS18C | -4105 |
| MRPS26 | -3891 |
| MRPL58 | -3776 |
| MRPS15 | -3732 |
| MRPL52 | -3676 |
| MRPS14 | -3575 |
| MRPL11 | -3457 |
| MRPL33 | -3419 |
| MRPL51 | -3240 |
| MRPS5 | -2925 |
| MRPS33 | -2760 |
| MRPL45 | -2620 |
| MRPL18 | -2588 |
| OXA1L | -2469 |
| MRPS9 | -2449 |
| MRPL48 | -1949 |
| MRPL35 | -1757 |
| MRPL21 | -1490 |
| MRPL30 | -1292 |
| DAP3 | -1255 |
| MRPS36 | -836 |
| MRPS35 | -312 |
| MRPL50 | -182 |
| MRPS30 | 125 |
| MRPL19 | 782 |
| MRPL1 | 1222 |
| MRPL32 | 1711 |
| MT-RNR1 | 2469 |
| MRPS25 | 2586 |
| MRPS28 | 2930 |
| GFM1 | 3529 |
| PTCD3 | 3730 |
| MRPL39 | 4422 |
| MRPS31 | 4480 |
| MRPL42 | 6674 |
| MT-RNR2 | 8527 |
Mitochondrial translation initiation
| 699 | |
|---|---|
| set | Mitochondrial translation initiation |
| setSize | 90 |
| pANOVA | 1.46e-14 |
| s.dist | -0.469 |
| p.adjustANOVA | 5.59e-13 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| MRPS6 | -8791 |
| MRPL38 | -8772 |
| MRPS34 | -8726 |
| ERAL1 | -8635 |
| MRPS24 | -8489 |
| MRPL57 | -8452 |
| MRPL41 | -8451 |
| MRPL4 | -8434 |
| MRPL12 | -8422 |
| AURKAIP1 | -8335 |
| MRPL10 | -8223 |
| MRPL34 | -8071 |
| MRPL43 | -8060 |
| MRPL2 | -8039 |
| MRPL16 | -7965 |
| MRPS16 | -7777 |
| MRPL20 | -7416 |
| MRPL23 | -7387 |
| MRPS18A | -7353 |
| MRPS7 | -7107 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MRPS6 | -8791 |
| MRPL38 | -8772 |
| MRPS34 | -8726 |
| ERAL1 | -8635 |
| MRPS24 | -8489 |
| MRPL57 | -8452 |
| MRPL41 | -8451 |
| MRPL4 | -8434 |
| MRPL12 | -8422 |
| AURKAIP1 | -8335 |
| MRPL10 | -8223 |
| MRPL34 | -8071 |
| MRPL43 | -8060 |
| MRPL2 | -8039 |
| MRPL16 | -7965 |
| MRPS16 | -7777 |
| MRPL20 | -7416 |
| MRPL23 | -7387 |
| MRPS18A | -7353 |
| MRPS7 | -7107 |
| MRPS11 | -7057 |
| MRPS18B | -7020 |
| MRPL14 | -6937 |
| MRPS12 | -6931 |
| MRPL49 | -6736 |
| MRPL40 | -6680 |
| MRPL54 | -6656 |
| MRPL22 | -6642 |
| CHCHD1 | -6474 |
| MRPS2 | -6344 |
| MRPL55 | -6245 |
| MRPL53 | -6232 |
| MRPL24 | -6045 |
| MRPL17 | -6025 |
| GADD45GIP1 | -6013 |
| MRPL9 | -5907 |
| MRPL27 | -5620 |
| MRPS23 | -5587 |
| MRPS17 | -5568 |
| MRPL46 | -5557 |
| MRPL37 | -5406 |
| MRPL28 | -5240 |
| MRPL3 | -5226 |
| MRPL36 | -4842 |
| MRPS22 | -4795 |
| MRPL13 | -4750 |
| MRPS27 | -4548 |
| MRPL15 | -4532 |
| MRPS21 | -4522 |
| MRPS10 | -4427 |
| MRPL47 | -4298 |
| MRPL44 | -4200 |
| MRPS18C | -4105 |
| MRPS26 | -3891 |
| MRPL58 | -3776 |
| MRPS15 | -3732 |
| MRPL52 | -3676 |
| MRPS14 | -3575 |
| MRPL11 | -3457 |
| MRPL33 | -3419 |
| MTIF2 | -3276 |
| MRPL51 | -3240 |
| MRPS5 | -2925 |
| MRPS33 | -2760 |
| MRPL45 | -2620 |
| MRPL18 | -2588 |
| OXA1L | -2469 |
| MRPS9 | -2449 |
| MRPL48 | -1949 |
| MRPL35 | -1757 |
| MRPL21 | -1490 |
| MRPL30 | -1292 |
| DAP3 | -1255 |
| MRPS36 | -836 |
| MRPS35 | -312 |
| MRPL50 | -182 |
| MRPS30 | 125 |
| MRPL19 | 782 |
| MTFMT | 1111 |
| MRPL1 | 1222 |
| MRPL32 | 1711 |
| MT-RNR1 | 2469 |
| MRPS25 | 2586 |
| MRPS28 | 2930 |
| PTCD3 | 3730 |
| MRPL39 | 4422 |
| MRPS31 | 4480 |
| MTIF3 | 5760 |
| MRPL42 | 6674 |
| MT-RNR2 | 8527 |
Fc epsilon receptor (FCERI) signaling
| 404 | |
|---|---|
| set | Fc epsilon receptor (FCERI) signaling |
| setSize | 165 |
| pANOVA | 1.66e-14 |
| s.dist | -0.346 |
| p.adjustANOVA | 6.19e-13 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| IGHV1-2 | -8953 |
| IGHV1-46 | -8910 |
| IGKV2D-28 | -8875 |
| IGKV3-11 | -8864 |
| IGKV1D-39 | -8828 |
| IGLV3-21 | -8806 |
| IGLV3-25 | -8773 |
| PIK3R2 | -8767 |
| IGHV3-33 | -8608 |
| MS4A2 | -8592 |
| IGLV2-14 | -8572 |
| PSMD3 | -8328 |
| PSMD8 | -8149 |
| FCER1G | -8128 |
| IGLV1-40 | -8088 |
| VAV1 | -7822 |
| RASGRP4 | -7795 |
| PSMB10 | -7709 |
| MAP2K7 | -7697 |
| PSMB5 | -7576 |
| IGKV3-15 | -7403 |
| IKBKG | -7367 |
| PSME3 | -7280 |
| PSMB2 | -7268 |
| GRB2 | -7191 |
| PSMD2 | -7104 |
| IGHV3-11 | -7017 |
| UBA52 | -6880 |
| PSMB6 | -6709 |
| PSMB3 | -6647 |
| LAT2 | -6615 |
| BTK | -6612 |
| PIK3R1 | -6564 |
| PSMD4 | -6452 |
| TAB1 | -6350 |
| PSMF1 | -6332 |
| MAPK3 | -6329 |
| SYK | -6217 |
| UBB | -6193 |
| PSMC5 | -6143 |
| PSMA7 | -6082 |
| PSMB7 | -5953 |
| PSMC4 | -5866 |
| GAB2 | -5845 |
| PSMC3 | -5726 |
| ITPR3 | -5506 |
| PSMB1 | -5473 |
| LCP2 | -5202 |
| PSMB4 | -5168 |
| HRAS | -4955 |
| FYN | -4854 |
| SKP1 | -4737 |
| IGKV1-33 | -4702 |
| PSMD9 | -4655 |
| PSMC2 | -4179 |
| LAT | -4104 |
| RELA | -4097 |
| PSMD10 | -3849 |
| BTRC | -3694 |
| RAC1 | -3331 |
| PAK1 | -3309 |
| PSMA6 | -3225 |
| TXK | -3035 |
| PSME1 | -3031 |
| LYN | -2889 |
| UBE2D2 | -2735 |
| PSMD7 | -2731 |
| PSMA5 | -2649 |
| PSMC1 | -2604 |
| RASGRP2 | -2558 |
| FBXW11 | -2408 |
| PSMD14 | -2133 |
| NFATC3 | -1875 |
| PSMD1 | -1782 |
| PSMA4 | -1756 |
| PSME2 | -1591 |
| PSMD11 | -1483 |
| PSMD5 | -1433 |
| PSMA2 | -1286 |
| CARD11 | -915 |
| VAV2 | -840 |
| RASGRP1 | -813 |
| CDC34 | -803 |
| PPP3CB | -797 |
| PSMD13 | -754 |
| AHCYL1 | -485 |
| NFATC1 | -480 |
| PSMB8 | -235 |
| PIK3CB | -106 |
| PSME4 | -48 |
| PSMD6 | 26 |
| PDPK1 | 33 |
| NFKBIA | 181 |
| RPS27A | 229 |
| PSMA1 | 379 |
| NFKB1 | 503 |
| TEC | 533 |
| MAP2K4 | 772 |
| PPP3CA | 858 |
| MAP3K7 | 1306 |
| CUL1 | 1406 |
| MAPK1 | 1610 |
| CALM1 | 1638 |
| UBE2N | 1734 |
| NRAS | 1742 |
| IKBKB | 1755 |
| GRAP2 | 1775 |
| TAB2 | 1818 |
| VAV3 | 1970 |
| PIK3CA | 2176 |
| UBE2V1 | 2277 |
| MAPK9 | 2439 |
| CHUK | 2486 |
| PAK2 | 2552 |
| UBC | 3246 |
| MAP3K1 | 3619 |
| PSMD12 | 3658 |
| PSMC6 | 3801 |
| KRAS | 3903 |
| NFATC2 | 3997 |
| ITPR2 | 4036 |
| PRKCQ | 4076 |
| PSMB9 | 4121 |
| TAB3 | 4183 |
| SHC1 | 4317 |
| PSMA3 | 5077 |
| SEM1 | 5372 |
| UBE2D1 | 5427 |
| SOS1 | 5452 |
| MAPK8 | 5565 |
| PPP3R1 | 5668 |
| PLCG1 | 5830 |
| ITK | 5899 |
| MALT1 | 6698 |
| TRAF6 | 7237 |
| BCL10 | 8277 |
| FOS | 8474 |
| FCER1A | 8672 |
| PLCG2 | 8985 |
| ITPR1 | 9487 |
| JUN | 9573 |
| MAPK10 | 9718 |
FCERI mediated Ca+2 mobilization
| 380 | |
|---|---|
| set | FCERI mediated Ca+2 mobilization |
| setSize | 64 |
| pANOVA | 2.01e-14 |
| s.dist | -0.553 |
| p.adjustANOVA | 7.29e-13 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| IGHV1-2 | -8953 |
| IGHV1-46 | -8910 |
| IGKV2D-28 | -8875 |
| IGKV3-11 | -8864 |
| IGKV1D-39 | -8828 |
| IGLV3-21 | -8806 |
| IGLV3-25 | -8773 |
| IGHV3-33 | -8608 |
| IGLV2-14 | -8572 |
| IGLV1-40 | -8088 |
| VAV1 | -7822 |
| IGKV3-15 | -7403 |
| GRB2 | -7191 |
| IGHV3-11 | -7017 |
| BTK | -6612 |
| SYK | -6217 |
| ITPR3 | -5506 |
| LCP2 | -5202 |
| IGKV1-33 | -4702 |
| LAT | -4104 |
| TXK | -3035 |
| LYN | -2889 |
| NFATC3 | -1875 |
| VAV2 | -840 |
| PPP3CB | -797 |
| AHCYL1 | -485 |
| NFATC1 | -480 |
| TEC | 533 |
| PPP3CA | 858 |
| CALM1 | 1638 |
| GRAP2 | 1775 |
| VAV3 | 1970 |
| NFATC2 | 3997 |
| ITPR2 | 4036 |
| SHC1 | 4317 |
| SOS1 | 5452 |
| PPP3R1 | 5668 |
| PLCG1 | 5830 |
| ITK | 5899 |
| PLCG2 | 8985 |
| ITPR1 | 9487 |
Cellular responses to stimuli
| 180 | |
|---|---|
| set | Cellular responses to stimuli |
| setSize | 676 |
| pANOVA | 3.22e-14 |
| s.dist | -0.171 |
| p.adjustANOVA | 1.14e-12 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| MT1E | -9136 |
| NCF1 | -9092 |
| NUDT2 | -9056 |
| MAPK7 | -9047 |
| AKT1S1 | -9040 |
| CDKN2B | -9032 |
| HM13 | -9000 |
| IGFBP1 | -8984 |
| RPS26 | -8966 |
| MT1X | -8940 |
| RPA1 | -8931 |
| YIF1A | -8928 |
| MLST8 | -8926 |
| SOD3 | -8904 |
| KDELR3 | -8886 |
| CA9 | -8825 |
| P4HB | -8801 |
| MYDGF | -8769 |
| CARM1 | -8755 |
| CYBA | -8747 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MT1E | -9136 |
| NCF1 | -9092 |
| NUDT2 | -9056 |
| MAPK7 | -9047 |
| AKT1S1 | -9040 |
| CDKN2B | -9032 |
| HM13 | -9000 |
| IGFBP1 | -8984 |
| RPS26 | -8966 |
| MT1X | -8940 |
| RPA1 | -8931 |
| YIF1A | -8928 |
| MLST8 | -8926 |
| SOD3 | -8904 |
| KDELR3 | -8886 |
| CA9 | -8825 |
| P4HB | -8801 |
| MYDGF | -8769 |
| CARM1 | -8755 |
| CYBA | -8747 |
| NUP210 | -8727 |
| APOB | -8671 |
| HYOU1 | -8670 |
| EXOSC4 | -8667 |
| SEC13 | -8653 |
| ATP6V0E2 | -8624 |
| MT1F | -8607 |
| TPP1 | -8589 |
| SURF1 | -8554 |
| NCOR2 | -8458 |
| ATP6V0C | -8415 |
| ATP6V1F | -8374 |
| HDGF | -8366 |
| KLHDC3 | -8362 |
| PSMD3 | -8328 |
| TLN1 | -8319 |
| CRTC1 | -8307 |
| COX8A | -8260 |
| MT1M | -8259 |
| TACO1 | -8234 |
| FKBP5 | -8210 |
| MAPKAPK3 | -8188 |
| GSK3A | -8163 |
| DCTN1 | -8155 |
| PSMD8 | -8149 |
| WDR24 | -8081 |
| CSNK2B | -8078 |
| RPA3 | -8040 |
| RPS4X | -8028 |
| SLC46A1 | -7928 |
| SRPRB | -7913 |
| POM121C | -7894 |
| TFDP2 | -7850 |
| MT1G | -7844 |
| HMGA1 | -7808 |
| KEAP1 | -7807 |
| RXRA | -7774 |
| TPR | -7773 |
| SRPRA | -7771 |
| PRDX2 | -7763 |
| CREB3 | -7757 |
| RPS19BP1 | -7740 |
| HSPA1L | -7723 |
| PSMB10 | -7709 |
| GPX1 | -7708 |
| DCTN3 | -7698 |
| MAP2K7 | -7697 |
| XBP1 | -7696 |
| GSTP1 | -7676 |
| EIF2AK1 | -7634 |
| SYVN1 | -7632 |
| PSMB5 | -7576 |
| HIRA | -7571 |
| GPX7 | -7527 |
| CUL7 | -7521 |
| KAT5 | -7497 |
| COX6B1 | -7448 |
| PTK6 | -7435 |
| VENTX | -7419 |
| DCTN5 | -7397 |
| ARFGAP1 | -7381 |
| LAMTOR1 | -7337 |
| DCTN2 | -7295 |
| PSME3 | -7280 |
| PSMB2 | -7268 |
| CDKN2A | -7189 |
| NUP62 | -7186 |
| COX6A1 | -7180 |
| CAPZB | -7174 |
| PSMD2 | -7104 |
| SOD1 | -7080 |
| PDIA6 | -7070 |
| ANAPC11 | -7053 |
| ATP6V0E1 | -7030 |
| HMOX2 | -7026 |
| AAAS | -7005 |
| BAG1 | -6939 |
| BLVRB | -6922 |
| PRKCD | -6909 |
| UBA52 | -6880 |
| TXN2 | -6874 |
| TCIRG1 | -6863 |
| COX5B | -6747 |
| COX5A | -6735 |
| PSMB6 | -6709 |
| SESN1 | -6704 |
| DYNLL2 | -6690 |
| CALR | -6689 |
| RPS6KA1 | -6676 |
| HSPA8 | -6665 |
| HERPUD1 | -6659 |
| NDUFA4 | -6655 |
| PSMB3 | -6647 |
| LAMTOR2 | -6641 |
| LAMTOR4 | -6618 |
| ELOB | -6600 |
| RRAGA | -6599 |
| HDAC3 | -6566 |
| MT2A | -6469 |
| DYNLL1 | -6465 |
| PSMD4 | -6452 |
| COX7B | -6445 |
| PRDX1 | -6420 |
| NUP88 | -6417 |
| NCF4 | -6412 |
| ATP6V0B | -6404 |
| RPL26L1 | -6364 |
| ACTR1A | -6346 |
| PSMF1 | -6332 |
| MAPK3 | -6329 |
| CBX6 | -6278 |
| MIOS | -6238 |
| POM121 | -6233 |
| H2BC12 | -6223 |
| GOSR2 | -6207 |
| NPRL3 | -6202 |
| UBB | -6193 |
| TXNRD2 | -6172 |
| PSMC5 | -6143 |
| ATP6V0D1 | -6117 |
| PSMA7 | -6082 |
| CRYAB | -6036 |
| TP53 | -6010 |
| TXNIP | -5982 |
| RAD50 | -5975 |
| PSMB7 | -5953 |
| EXOSC3 | -5942 |
| PSMC4 | -5866 |
| ITFG2 | -5814 |
| RPL39L | -5767 |
| ADD1 | -5751 |
| PPARA | -5728 |
| PSMC3 | -5726 |
| KHSRP | -5705 |
| MBTPS1 | -5686 |
| STIP1 | -5608 |
| H1-2 | -5529 |
| VCP | -5509 |
| PSMB1 | -5473 |
| DEDD2 | -5394 |
| TNFRSF21 | -5381 |
| EXOSC5 | -5349 |
| RPA2 | -5337 |
| NPRL2 | -5330 |
| NUP93 | -5327 |
| COX7C | -5326 |
| SCO1 | -5322 |
| PRDX6 | -5286 |
| ATOX1 | -5254 |
| COX4I1 | -5248 |
| RPS14 | -5234 |
| PHC2 | -5219 |
| CTDSP2 | -5213 |
| RPTOR | -5181 |
| PSMB4 | -5168 |
| NUP37 | -5152 |
| PLA2G4B | -5041 |
| TINF2 | -5009 |
| HIF1AN | -4992 |
| PREB | -4989 |
| SCO2 | -4979 |
| GPX8 | -4952 |
| ACADVL | -4950 |
| FKBP14 | -4925 |
| RPL27 | -4912 |
| RPL27A | -4896 |
| COX19 | -4867 |
| RPL35 | -4745 |
| SKP1 | -4737 |
| CRTC2 | -4734 |
| NUP188 | -4718 |
| LAMTOR5 | -4714 |
| COX16 | -4673 |
| RING1 | -4669 |
| CCAR2 | -4668 |
| CDK4 | -4665 |
| PSMD9 | -4655 |
| FAU | -4625 |
| BLVRA | -4615 |
| EXOSC6 | -4580 |
| NRIP1 | -4579 |
| COX14 | -4545 |
| DNAJB11 | -4537 |
| ATP6V1G1 | -4500 |
| RBX1 | -4435 |
| HMGA2 | -4425 |
| HSBP1 | -4424 |
| SEC31A | -4403 |
| HSPA5 | -4392 |
| DCTN6 | -4386 |
| ATP6V1D | -4357 |
| DYNC1H1 | -4355 |
| HSP90B1 | -4345 |
| ARNT | -4311 |
| HSPA2 | -4259 |
| PRDX5 | -4243 |
| COX6C | -4240 |
| WIPI1 | -4183 |
| PSMC2 | -4179 |
| RPL13 | -4148 |
| NFYC | -4144 |
| DNAJA4 | -4131 |
| TATDN2 | -4101 |
| RELA | -4097 |
| RPL8 | -4049 |
| RPS18 | -4032 |
| RPS10 | -4028 |
| GCN1 | -4027 |
| RPS29 | -4009 |
| EXOSC1 | -3990 |
| TERF2 | -3986 |
| RPS21 | -3873 |
| CYBB | -3854 |
| PSMD10 | -3849 |
| CREB3L4 | -3820 |
| HSF1 | -3763 |
| RPS5 | -3741 |
| ANAPC16 | -3739 |
| TRIB3 | -3731 |
| WFS1 | -3671 |
| SERP1 | -3659 |
| CDKN2C | -3607 |
| NUP214 | -3603 |
| BAG5 | -3596 |
| RPS11 | -3569 |
| RPL15 | -3543 |
| RPLP1 | -3524 |
| RPL36 | -3523 |
| RPL4 | -3472 |
| ANAPC2 | -3380 |
| H2BC5 | -3370 |
| RPL31 | -3359 |
| COX11 | -3330 |
| IMPACT | -3313 |
| RPL23 | -3274 |
| HDAC6 | -3228 |
| PSMA6 | -3225 |
| RPL10 | -3210 |
| H2AJ | -3209 |
| RPS25 | -3191 |
| RPL7A | -3188 |
| ATP6V1E1 | -3137 |
| MED1 | -3129 |
| RPL12 | -3105 |
| LY96 | -3104 |
| SSR1 | -3101 |
| TXNRD1 | -3072 |
| RPL29 | -3065 |
| RAE1 | -3056 |
| CDC26 | -3045 |
| RPS19 | -3032 |
| PSME1 | -3031 |
| NUP98 | -3024 |
| RPL30 | -3017 |
| TXN | -3012 |
| RPL19 | -2986 |
| RPS8 | -2974 |
| EGLN2 | -2959 |
| KPTN | -2883 |
| RPL35A | -2878 |
| RPLP0 | -2877 |
| ATF6 | -2851 |
| CREBBP | -2822 |
| EXOSC7 | -2747 |
| UBE2D2 | -2735 |
| PSMD7 | -2731 |
| RPL18 | -2728 |
| CCNE1 | -2722 |
| RPL18A | -2719 |
| CDKN2D | -2714 |
| EXOSC2 | -2713 |
| PPP2R5B | -2711 |
| RPL13A | -2708 |
| RPL38 | -2691 |
| RPS27 | -2657 |
| PSMA5 | -2649 |
| ATP6V1B2 | -2647 |
| PSMC1 | -2604 |
| MRPL18 | -2588 |
| HSPA12A | -2581 |
| RPS17 | -2555 |
| AR | -2536 |
| RPS23 | -2494 |
| RPS15 | -2484 |
| EHMT2 | -2459 |
| ANAPC7 | -2426 |
| YWHAE | -2405 |
| RPL34 | -2389 |
| FZR1 | -2354 |
| RPS3A | -2337 |
| RPL28 | -2326 |
| CRTC3 | -2295 |
| ASF1A | -2268 |
| RPLP2 | -2239 |
| TLR4 | -2238 |
| NUP85 | -2218 |
| STAT3 | -2208 |
| NCOR1 | -2161 |
| AGO1 | -2148 |
| PSMD14 | -2133 |
| RPL32 | -2131 |
| CCS | -2114 |
| RPL3L | -2091 |
| RPL23A | -2081 |
| RPS12 | -2076 |
| RPS15A | -2051 |
| MBTPS2 | -2040 |
| TFDP1 | -2011 |
| NDC1 | -1920 |
| EIF2AK4 | -1885 |
| LIMD1 | -1787 |
| PSMD1 | -1782 |
| RPL10A | -1766 |
| LAMTOR3 | -1758 |
| PSMA4 | -1756 |
| RPS20 | -1746 |
| RPL37A | -1736 |
| MAP2K3 | -1696 |
| RPS28 | -1692 |
| RPS3 | -1643 |
| FKBP4 | -1639 |
| EEF1A1 | -1605 |
| CXXC1 | -1602 |
| PSME2 | -1591 |
| RPS7 | -1576 |
| ANAPC10 | -1560 |
| MT1H | -1548 |
| COX7A2L | -1534 |
| RPL37 | -1517 |
| PSMD11 | -1483 |
| SULT1A3 | -1481 |
| DCSTAMP | -1446 |
| PSMD5 | -1433 |
| RPS24 | -1390 |
| E2F1 | -1381 |
| WDR59 | -1378 |
| SOD2 | -1375 |
| ANAPC5 | -1362 |
| NCF2 | -1349 |
| HSPA13 | -1326 |
| PSMA2 | -1286 |
| RPL3 | -1283 |
| GFPT1 | -1256 |
| RPS6 | -1245 |
| SIN3A | -1221 |
| GPX3 | -1215 |
| MAPK14 | -1200 |
| ANAPC15 | -1199 |
| CSNK2A1 | -1195 |
| MT-CO3 | -1115 |
| CDC23 | -1090 |
| SCMH1 | -1046 |
| RPL26 | -1044 |
| CHD9 | -1030 |
| COX18 | -1013 |
| MT-CO2 | -988 |
| ABCC1 | -953 |
| NCOA6 | -932 |
| RPL21 | -907 |
| ACD | -874 |
| RPL11 | -848 |
| RPL41 | -812 |
| CAPZA2 | -802 |
| PSMD13 | -754 |
| NUP205 | -738 |
| NR1D1 | -676 |
| EXTL3 | -649 |
| NUP42 | -641 |
| CREB3L2 | -632 |
| RPL17 | -614 |
| HIGD1A | -592 |
| MTOR | -561 |
| ZBTB17 | -554 |
| PARN | -498 |
| RPL6 | -483 |
| RPS16 | -451 |
| RPS2 | -411 |
| ACTR10 | -373 |
| RPL14 | -367 |
| UBN1 | -309 |
| FBXL17 | -292 |
| RPL24 | -289 |
| EP300 | -244 |
| PSMB8 | -235 |
| EIF2AK3 | -184 |
| PRDX3 | -171 |
| RPL5 | -160 |
| NUP153 | -156 |
| H2AZ1 | -91 |
| DNAJB6 | -83 |
| SMARCD3 | -65 |
| CABIN1 | -63 |
| PSME4 | -48 |
| CAMK2B | -37 |
| RBBP7 | -26 |
| RPS9 | 11 |
| PSMD6 | 26 |
| POT1 | 44 |
| DCTN4 | 48 |
| SP1 | 60 |
| ASNS | 108 |
| CSNK2A2 | 111 |
| BAG4 | 122 |
| RHEB | 132 |
| H2AC6 | 204 |
| RPS27L | 222 |
| RPS27A | 229 |
| FNIP2 | 295 |
| ATP6V1G2 | 311 |
| RRAGC | 329 |
| RPL22 | 345 |
| PSMA1 | 379 |
| RPL39 | 390 |
| H2BU1 | 397 |
| CAMK2A | 491 |
| NFKB1 | 503 |
| TBL1X | 506 |
| H2AZ2 | 509 |
| RPS4Y1 | 514 |
| BMT2 | 531 |
| CDC16 | 578 |
| SIN3B | 588 |
| VHL | 652 |
| MT-CO1 | 720 |
| MINK1 | 762 |
| EIF2S1 | 771 |
| MAP2K4 | 772 |
| EED | 800 |
| ATP6V1H | 924 |
| MAPKAPK2 | 933 |
| SERPINH1 | 960 |
| RPS13 | 1006 |
| ATM | 1033 |
| EHMT1 | 1068 |
| PTGES3 | 1088 |
| RBBP4 | 1093 |
| DNAJB9 | 1151 |
| DNAJC3 | 1382 |
| RRAGD | 1393 |
| CUL1 | 1406 |
| HSP90AB1 | 1424 |
| SZT2 | 1465 |
| EXTL2 | 1487 |
| UBE2E1 | 1544 |
| CHAC1 | 1568 |
| MAPK1 | 1610 |
| CSRP1 | 1649 |
| HSPA4 | 1668 |
| HSPA14 | 1688 |
| CCNA2 | 1702 |
| MAPKAPK5 | 1712 |
| CAPZA1 | 1732 |
| RPL7 | 1738 |
| PDIA5 | 1745 |
| UBE2C | 1747 |
| EP400 | 1767 |
| H2BC21 | 1774 |
| RB1 | 1797 |
| GSR | 1865 |
| DNAJC7 | 1919 |
| BMI1 | 1962 |
| ATP6V1A | 2025 |
| NR3C1 | 2034 |
| HIF3A | 2112 |
| NUP155 | 2114 |
| NUP35 | 2129 |
| H2AC18 | 2134 |
| MAP3K5 | 2141 |
| NUP54 | 2157 |
| MTF1 | 2179 |
| TNIK | 2387 |
| MAPK9 | 2439 |
| RPS6KA2 | 2440 |
| NUP43 | 2453 |
| DDX11 | 2464 |
| NOX4 | 2465 |
| FLCN | 2571 |
| HSPA4L | 2574 |
| ST13 | 2595 |
| DYNC1LI2 | 2656 |
| RPL36A | 2688 |
| TGS1 | 2707 |
| E2F2 | 2726 |
| SESN2 | 2828 |
| ATP6V1C1 | 2865 |
| BACH1 | 2913 |
| RAI1 | 2960 |
| STAP2 | 2966 |
| CREBRF | 2996 |
| DNAJA2 | 3007 |
| TERF1 | 3026 |
| EIF2S2 | 3109 |
| ATP6V1E2 | 3118 |
| ID1 | 3145 |
| RANBP2 | 3171 |
| RPSA | 3175 |
| HSPA9 | 3176 |
| DYNC1I2 | 3198 |
| CLOCK | 3204 |
| ATF5 | 3227 |
| UBC | 3246 |
| ELOC | 3260 |
| CREB1 | 3370 |
| TNRC6C | 3379 |
| CITED2 | 3385 |
| ATP6V0D2 | 3413 |
| ERN1 | 3463 |
| CEBPB | 3467 |
| NCOA2 | 3470 |
| EXOSC8 | 3486 |
| BAG2 | 3549 |
| MOV10 | 3555 |
| ATP7A | 3594 |
| DCP2 | 3604 |
| EDEM1 | 3611 |
| DDIT3 | 3638 |
| CAT | 3646 |
| PSMD12 | 3658 |
| NUP133 | 3662 |
| EIF2S3 | 3667 |
| CUL2 | 3685 |
| HSP90AA1 | 3693 |
| UBE2D3 | 3753 |
| TERF2IP | 3798 |
| PSMC6 | 3801 |
| SLC38A9 | 3808 |
| NLRP3 | 3857 |
| RPS6KA3 | 3890 |
| CEBPG | 3920 |
| NCOA1 | 3941 |
| ATF2 | 3946 |
| SUZ12 | 3951 |
| RNF2 | 3972 |
| H3-3A | 4015 |
| NOX5 | 4104 |
| PSMB9 | 4121 |
| NBN | 4173 |
| HMOX1 | 4200 |
| ATF4 | 4212 |
| EZH2 | 4236 |
| SHC1 | 4317 |
| SEH1L | 4352 |
| PHC1 | 4367 |
| ANAPC1 | 4391 |
| LRPPRC | 4418 |
| CDC27 | 4464 |
| NUP58 | 4488 |
| HIKESHI | 4529 |
| CCNE2 | 4551 |
| CUL3 | 4595 |
| DIS3 | 4635 |
| ERO1A | 4711 |
| RPL36AL | 4730 |
| CBX4 | 4782 |
| DNAJA1 | 4799 |
| RPL9 | 4853 |
| E2F3 | 5003 |
| PGR | 5027 |
| PSMA3 | 5077 |
| RPL22L1 | 5078 |
| NUP160 | 5248 |
| MDM2 | 5371 |
| SEM1 | 5372 |
| UBE2S | 5380 |
| UBE2D1 | 5427 |
| HELZ2 | 5538 |
| MAFK | 5544 |
| MAPK8 | 5565 |
| GSK3B | 5609 |
| WTIP | 5680 |
| HBA1 | 5744 |
| NUP50 | 5758 |
| HBB | 5795 |
| RRAGB | 5856 |
| CBX2 | 5858 |
| MEF2D | 6088 |
| ATP6V1B1 | 6096 |
| PHC3 | 6121 |
| MAP2K6 | 6128 |
| CREB3L1 | 6131 |
| HSPH1 | 6134 |
| DNAJC2 | 6147 |
| CDK6 | 6175 |
| CAMK2G | 6254 |
| DYNC1LI1 | 6270 |
| DEPDC5 | 6304 |
| AGO4 | 6428 |
| MT1A | 6461 |
| TNRC6A | 6524 |
| TBL1XR1 | 6553 |
| PPARGC1A | 6593 |
| RORA | 6791 |
| AGO3 | 6796 |
| ANAPC4 | 6889 |
| MRE11 | 6908 |
| NR3C2 | 7022 |
| ATP6V1C2 | 7031 |
| EGLN1 | 7105 |
| FNIP1 | 7191 |
| CXCL8 | 7197 |
| EXOSC9 | 7206 |
| COL4A6 | 7219 |
| HIF1A | 7278 |
| TSPYL2 | 7327 |
| CYCS | 7385 |
| ERF | 7400 |
| HSPB8 | 7428 |
| TNRC6B | 7523 |
| HSPA12B | 7542 |
| NPAS2 | 7575 |
| LMNA | 7628 |
| LMNB1 | 7662 |
| DYNC1I1 | 7687 |
| COX20 | 7745 |
| SKP2 | 7870 |
| BAG3 | 7903 |
| H1-0 | 7919 |
| CDK2 | 8007 |
| CBX8 | 8025 |
| MEF2C | 8059 |
| XPO1 | 8102 |
| MDM4 | 8113 |
| NFYB | 8132 |
| NFYA | 8142 |
| SIRT1 | 8207 |
| EPAS1 | 8247 |
| AJUBA | 8282 |
| HSPA7 | 8400 |
| MAP4K4 | 8436 |
| FOS | 8474 |
| NFE2L2 | 8542 |
| CDKN1B | 8660 |
| HSPA6 | 8872 |
| ARNTL | 8892 |
| HSPA1B | 8917 |
| SH3BP4 | 9075 |
| GRB10 | 9089 |
| CAMK2D | 9106 |
| DNAJB1 | 9233 |
| NUP107 | 9235 |
| MAPK11 | 9361 |
| KDM6B | 9477 |
| EGLN3 | 9480 |
| ATR | 9507 |
| JUN | 9573 |
| VEGFA | 9645 |
| IGFBP7 | 9699 |
| MAPK10 | 9718 |
| ETS2 | 9750 |
| CCL2 | 9784 |
| CDKN1A | 9840 |
| IL6 | 9872 |
| ETS1 | 9885 |
| ATF3 | 9917 |
| HSPA1A | 9988 |
| PPP1R15A | 9997 |
Mitochondrial translation termination
| 700 | |
|---|---|
| set | Mitochondrial translation termination |
| setSize | 90 |
| pANOVA | 7.49e-14 |
| s.dist | -0.456 |
| p.adjustANOVA | 2.59e-12 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| MRPS6 | -8791 |
| MRPL38 | -8772 |
| MRPS34 | -8726 |
| ERAL1 | -8635 |
| MRPS24 | -8489 |
| MRPL57 | -8452 |
| MRPL41 | -8451 |
| MRPL4 | -8434 |
| MRPL12 | -8422 |
| AURKAIP1 | -8335 |
| MRPL10 | -8223 |
| MRPL34 | -8071 |
| MRPL43 | -8060 |
| MRPL2 | -8039 |
| MRPL16 | -7965 |
| MRPS16 | -7777 |
| MRPL20 | -7416 |
| MRPL23 | -7387 |
| MRPS18A | -7353 |
| MRPS7 | -7107 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MRPS6 | -8791 |
| MRPL38 | -8772 |
| MRPS34 | -8726 |
| ERAL1 | -8635 |
| MRPS24 | -8489 |
| MRPL57 | -8452 |
| MRPL41 | -8451 |
| MRPL4 | -8434 |
| MRPL12 | -8422 |
| AURKAIP1 | -8335 |
| MRPL10 | -8223 |
| MRPL34 | -8071 |
| MRPL43 | -8060 |
| MRPL2 | -8039 |
| MRPL16 | -7965 |
| MRPS16 | -7777 |
| MRPL20 | -7416 |
| MRPL23 | -7387 |
| MRPS18A | -7353 |
| MRPS7 | -7107 |
| MRPS11 | -7057 |
| MRPS18B | -7020 |
| MRPL14 | -6937 |
| MRPS12 | -6931 |
| MRPL49 | -6736 |
| MRPL40 | -6680 |
| MRPL54 | -6656 |
| MRPL22 | -6642 |
| CHCHD1 | -6474 |
| MRPS2 | -6344 |
| MRPL55 | -6245 |
| MRPL53 | -6232 |
| MRPL24 | -6045 |
| MRPL17 | -6025 |
| GADD45GIP1 | -6013 |
| MRPL9 | -5907 |
| MRPL27 | -5620 |
| MRPS23 | -5587 |
| MRPS17 | -5568 |
| MRPL46 | -5557 |
| MRPL37 | -5406 |
| MRPL28 | -5240 |
| MRPL3 | -5226 |
| MRPL36 | -4842 |
| MRPS22 | -4795 |
| MRPL13 | -4750 |
| MRPS27 | -4548 |
| MRPL15 | -4532 |
| MRPS21 | -4522 |
| MRPS10 | -4427 |
| MRPL47 | -4298 |
| MRPL44 | -4200 |
| MRPS18C | -4105 |
| MRPS26 | -3891 |
| MRPL58 | -3776 |
| MRPS15 | -3732 |
| MRPL52 | -3676 |
| MRPS14 | -3575 |
| MRPL11 | -3457 |
| MRPL33 | -3419 |
| MRPL51 | -3240 |
| MRPS5 | -2925 |
| MRPS33 | -2760 |
| MRPL45 | -2620 |
| MRPL18 | -2588 |
| OXA1L | -2469 |
| MRPS9 | -2449 |
| MRPL48 | -1949 |
| MRPL35 | -1757 |
| MRPL21 | -1490 |
| MRPL30 | -1292 |
| DAP3 | -1255 |
| MRPS36 | -836 |
| MRPS35 | -312 |
| MRPL50 | -182 |
| MRPS30 | 125 |
| MRPL19 | 782 |
| MRPL1 | 1222 |
| GFM2 | 1532 |
| MRPL32 | 1711 |
| MT-RNR1 | 2469 |
| MRPS25 | 2586 |
| MRPS28 | 2930 |
| PTCD3 | 3730 |
| MRPL39 | 4422 |
| MRPS31 | 4480 |
| MRRF | 5368 |
| MRPL42 | 6674 |
| MTRF1L | 7847 |
| MT-RNR2 | 8527 |
Diseases of metabolism
| 314 | |
|---|---|
| set | Diseases of metabolism |
| setSize | 209 |
| pANOVA | 9.33e-14 |
| s.dist | -0.299 |
| p.adjustANOVA | 3.15e-12 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| MUC20 | -9146 |
| ADAMTSL5 | -9072 |
| ALG3 | -9024 |
| CSF2RA | -8945 |
| GAA | -8936 |
| SBSPON | -8920 |
| PC | -8891 |
| DPM2 | -8879 |
| CTSA | -8873 |
| SEMA5A | -8863 |
| DOLK | -8850 |
| FMOD | -8843 |
| DAG1 | -8830 |
| PMM2 | -8777 |
| KERA | -8680 |
| ABCA3 | -8664 |
| NHLRC1 | -8617 |
| DHDDS | -8593 |
| THSD4 | -8579 |
| B4GAT1 | -8568 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MUC20 | -9146 |
| ADAMTSL5 | -9072 |
| ALG3 | -9024 |
| CSF2RA | -8945 |
| GAA | -8936 |
| SBSPON | -8920 |
| PC | -8891 |
| DPM2 | -8879 |
| CTSA | -8873 |
| SEMA5A | -8863 |
| DOLK | -8850 |
| FMOD | -8843 |
| DAG1 | -8830 |
| PMM2 | -8777 |
| KERA | -8680 |
| ABCA3 | -8664 |
| NHLRC1 | -8617 |
| DHDDS | -8593 |
| THSD4 | -8579 |
| B4GAT1 | -8568 |
| G6PC3 | -8561 |
| SDC3 | -8509 |
| HYAL1 | -8407 |
| ADAMTS15 | -8355 |
| GALK1 | -8324 |
| ADAMTS5 | -8283 |
| ADAMTS17 | -8231 |
| ALG12 | -8201 |
| GLB1 | -8189 |
| MPDU1 | -8150 |
| PRELP | -8076 |
| ALG1 | -8022 |
| GALNS | -7969 |
| ACY1 | -7941 |
| ADAMTSL3 | -7925 |
| C1GALT1 | -7908 |
| BGN | -7906 |
| POMC | -7890 |
| B3GALT6 | -7746 |
| ADAMTSL4 | -7685 |
| SGSH | -7668 |
| GPC6 | -7588 |
| MUC4 | -7552 |
| MOGS | -7465 |
| GUSB | -7411 |
| FDX1 | -7349 |
| CYP26B1 | -7214 |
| B3GAT3 | -7173 |
| ADAMTSL2 | -7159 |
| PGM1 | -7071 |
| TALDO1 | -7011 |
| CSPG4 | -7003 |
| KHK | -6980 |
| UBA52 | -6880 |
| GPC5 | -6778 |
| EXT2 | -6767 |
| LFNG | -6757 |
| HEXA | -6728 |
| DPAGT1 | -6669 |
| ADAMTS3 | -6521 |
| TBXAS1 | -6500 |
| TPMT | -6473 |
| NOTCH2 | -6449 |
| GGT1 | -6408 |
| MUC6 | -6359 |
| AHCY | -6338 |
| ALG2 | -6248 |
| B4GALT7 | -6219 |
| UBB | -6193 |
| ADAMTS7 | -6113 |
| NAGLU | -6035 |
| CYP1B1 | -6012 |
| ADAMTS16 | -5780 |
| MAN1B1 | -5730 |
| SDC1 | -5597 |
| POMGNT1 | -5565 |
| TCN2 | -5517 |
| CHST14 | -5507 |
| GYS1 | -5458 |
| HEXB | -5455 |
| GALE | -5230 |
| BTD | -5228 |
| POMT2 | -5184 |
| IDUA | -5179 |
| MPI | -5037 |
| CFP | -4887 |
| GNS | -4788 |
| ADAMTS10 | -4774 |
| SDC2 | -4765 |
| NEU1 | -4756 |
| SLC26A2 | -4703 |
| PAPSS2 | -4292 |
| MMACHC | -4234 |
| THBS2 | -4197 |
| POMT1 | -4165 |
| LMBRD1 | -4140 |
| CYP21A2 | -4060 |
| GYG1 | -3994 |
| DPM3 | -3983 |
| GALNT12 | -3979 |
| SLC37A4 | -3875 |
| FDX2 | -3811 |
| MCCC2 | -3793 |
| GSS | -3721 |
| CHST3 | -3720 |
| SDC4 | -3718 |
| EXT1 | -3644 |
| MGAT2 | -3597 |
| GBE1 | -3532 |
| MMAB | -3427 |
| CYP27B1 | -3398 |
| ADAMTS2 | -3363 |
| IDH1 | -3258 |
| C1GALT1C1 | -2997 |
| OGN | -2906 |
| RFT1 | -2817 |
| AMN | -2799 |
| SRD5A3 | -2797 |
| ARSB | -2736 |
| ALG8 | -2436 |
| DCXR | -2407 |
| HGSNAT | -2328 |
| ADAMTS8 | -2265 |
| PCCB | -2182 |
| FDXR | -2115 |
| AGRN | -2113 |
| ADAMTS6 | -2079 |
| MAOA | -2073 |
| VCAN | -1970 |
| CYP2R1 | -1921 |
| CD320 | -1842 |
| LUM | -1737 |
| ALG9 | -1588 |
| ALG11 | -1573 |
| CYP27A1 | -1397 |
| HLCS | -1371 |
| MUC1 | -1357 |
| GFPT1 | -1256 |
| ADAMTS14 | -1232 |
| MUC12 | -1066 |
| ADAMTS13 | -1058 |
| CHST6 | -856 |
| ACAN | -799 |
| OPLAH | -709 |
| B4GALT1 | -661 |
| ADAMTS19 | -636 |
| MMUT | -618 |
| NUS1 | -501 |
| CYP11A1 | -443 |
| CYP2U1 | -276 |
| GCLC | 180 |
| RPS27A | 229 |
| DCN | 553 |
| GNE | 621 |
| GPC1 | 659 |
| HSPG2 | 885 |
| GYG2 | 916 |
| ALG14 | 928 |
| GALT | 941 |
| ST3GAL3 | 1150 |
| IDS | 1175 |
| SFTPD | 1388 |
| MTRR | 1643 |
| MMADHC | 1787 |
| DPM1 | 1909 |
| EPM2A | 2084 |
| CSF2RB | 2267 |
| B3GLCT | 2794 |
| GPC4 | 3048 |
| SPON1 | 3126 |
| UBC | 3246 |
| ACACA | 3247 |
| GCLM | 3292 |
| SPON2 | 3448 |
| MCCC1 | 3451 |
| MMAA | 3645 |
| PPP1R3C | 4413 |
| RPIA | 4687 |
| OMD | 4868 |
| MTR | 5215 |
| ALG13 | 5249 |
| GPC2 | 5376 |
| SLC35D1 | 5788 |
| GALNT3 | 5872 |
| LARGE1 | 6267 |
| ABCD4 | 6343 |
| THSD7A | 6817 |
| CYP19A1 | 6880 |
| CYP7B1 | 7672 |
| THSD1 | 7840 |
| ADAMTS12 | 8006 |
| CHSY1 | 8230 |
| SSPOP | 8392 |
| GPC3 | 8446 |
| PCCA | 8572 |
| CUBN | 8669 |
| NOTCH3 | 8708 |
| ALG6 | 8828 |
| NOTCH1 | 9665 |
| MUC3A | 9677 |
| ADAMTS1 | 9694 |
| FMO3 | 9829 |
| ADAMTSL1 | 9951 |
| ADAMTS4 | 9961 |
| SEMA5B | 10059 |
| ADAMTS18 | 10060 |
| THBS1 | 10064 |
| ADAMTS9 | 10114 |
| NOTCH4 | 10129 |
Mitochondrial translation
| 697 | |
|---|---|
| set | Mitochondrial translation |
| setSize | 96 |
| pANOVA | 1.08e-13 |
| s.dist | -0.439 |
| p.adjustANOVA | 3.56e-12 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| MRPS6 | -8791 |
| MRPL38 | -8772 |
| MRPS34 | -8726 |
| ERAL1 | -8635 |
| MRPS24 | -8489 |
| MRPL57 | -8452 |
| MRPL41 | -8451 |
| MRPL4 | -8434 |
| MRPL12 | -8422 |
| AURKAIP1 | -8335 |
| TSFM | -8273 |
| MRPL10 | -8223 |
| MRPL34 | -8071 |
| MRPL43 | -8060 |
| MRPL2 | -8039 |
| MRPL16 | -7965 |
| MRPS16 | -7777 |
| MRPL20 | -7416 |
| MRPL23 | -7387 |
| MRPS18A | -7353 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MRPS6 | -8791 |
| MRPL38 | -8772 |
| MRPS34 | -8726 |
| ERAL1 | -8635 |
| MRPS24 | -8489 |
| MRPL57 | -8452 |
| MRPL41 | -8451 |
| MRPL4 | -8434 |
| MRPL12 | -8422 |
| AURKAIP1 | -8335 |
| TSFM | -8273 |
| MRPL10 | -8223 |
| MRPL34 | -8071 |
| MRPL43 | -8060 |
| MRPL2 | -8039 |
| MRPL16 | -7965 |
| MRPS16 | -7777 |
| MRPL20 | -7416 |
| MRPL23 | -7387 |
| MRPS18A | -7353 |
| MRPS7 | -7107 |
| MRPS11 | -7057 |
| MRPS18B | -7020 |
| MRPL14 | -6937 |
| MRPS12 | -6931 |
| MRPL49 | -6736 |
| MRPL40 | -6680 |
| MRPL54 | -6656 |
| MRPL22 | -6642 |
| CHCHD1 | -6474 |
| MRPS2 | -6344 |
| MRPL55 | -6245 |
| MRPL53 | -6232 |
| TUFM | -6084 |
| MRPL24 | -6045 |
| MRPL17 | -6025 |
| GADD45GIP1 | -6013 |
| MRPL9 | -5907 |
| MRPL27 | -5620 |
| MRPS23 | -5587 |
| MRPS17 | -5568 |
| MRPL46 | -5557 |
| MRPL37 | -5406 |
| MRPL28 | -5240 |
| MRPL3 | -5226 |
| MRPL36 | -4842 |
| MRPS22 | -4795 |
| MRPL13 | -4750 |
| MRPS27 | -4548 |
| MRPL15 | -4532 |
| MRPS21 | -4522 |
| MRPS10 | -4427 |
| MRPL47 | -4298 |
| MRPL44 | -4200 |
| MRPS18C | -4105 |
| MRPS26 | -3891 |
| MRPL58 | -3776 |
| MRPS15 | -3732 |
| MRPL52 | -3676 |
| MRPS14 | -3575 |
| MRPL11 | -3457 |
| MRPL33 | -3419 |
| MTIF2 | -3276 |
| MRPL51 | -3240 |
| MRPS5 | -2925 |
| MRPS33 | -2760 |
| MRPL45 | -2620 |
| MRPL18 | -2588 |
| OXA1L | -2469 |
| MRPS9 | -2449 |
| MRPL48 | -1949 |
| MRPL35 | -1757 |
| MRPL21 | -1490 |
| MRPL30 | -1292 |
| DAP3 | -1255 |
| MRPS36 | -836 |
| MRPS35 | -312 |
| MRPL50 | -182 |
| MRPS30 | 125 |
| MRPL19 | 782 |
| MTFMT | 1111 |
| MRPL1 | 1222 |
| GFM2 | 1532 |
| MRPL32 | 1711 |
| MT-RNR1 | 2469 |
| MRPS25 | 2586 |
| MRPS28 | 2930 |
| GFM1 | 3529 |
| PTCD3 | 3730 |
| MRPL39 | 4422 |
| MRPS31 | 4480 |
| MRRF | 5368 |
| MTIF3 | 5760 |
| MRPL42 | 6674 |
| MTRF1L | 7847 |
| MT-RNR2 | 8527 |
Respiratory electron transport
| 1065 | |
|---|---|
| set | Respiratory electron transport |
| setSize | 103 |
| pANOVA | 1.23e-13 |
| s.dist | -0.423 |
| p.adjustANOVA | 3.98e-12 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| SURF1 | -8554 |
| NDUFAF3 | -8511 |
| NDUFA11 | -8504 |
| CYC1 | -8353 |
| COX8A | -8260 |
| TACO1 | -8234 |
| ETFB | -8156 |
| UQCRC1 | -7995 |
| NDUFA13 | -7854 |
| NDUFB10 | -7825 |
| NDUFS7 | -7728 |
| UQCR10 | -7703 |
| NDUFB7 | -7699 |
| NDUFS8 | -7687 |
| SDHA | -7652 |
| NDUFC1 | -7608 |
| NDUFA1 | -7540 |
| UQCRFS1 | -7522 |
| COX6B1 | -7448 |
| NDUFA6 | -7341 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SURF1 | -8554 |
| NDUFAF3 | -8511 |
| NDUFA11 | -8504 |
| CYC1 | -8353 |
| COX8A | -8260 |
| TACO1 | -8234 |
| ETFB | -8156 |
| UQCRC1 | -7995 |
| NDUFA13 | -7854 |
| NDUFB10 | -7825 |
| NDUFS7 | -7728 |
| UQCR10 | -7703 |
| NDUFB7 | -7699 |
| NDUFS8 | -7687 |
| SDHA | -7652 |
| NDUFC1 | -7608 |
| NDUFA1 | -7540 |
| UQCRFS1 | -7522 |
| COX6B1 | -7448 |
| NDUFA6 | -7341 |
| COX6A1 | -7180 |
| NDUFC2 | -7108 |
| UQCR11 | -6919 |
| COX5B | -6747 |
| COX5A | -6735 |
| NDUFA3 | -6716 |
| SDHC | -6686 |
| NDUFA4 | -6655 |
| NDUFA8 | -6633 |
| NDUFS5 | -6581 |
| MT-ND6 | -6516 |
| NDUFB11 | -6495 |
| COX7B | -6445 |
| NDUFV3 | -6428 |
| SDHB | -6352 |
| NDUFB4 | -6053 |
| UQCRQ | -6043 |
| NDUFA2 | -6040 |
| NDUFB2 | -5967 |
| NDUFS3 | -5954 |
| NDUFAB1 | -5886 |
| MT-ND5 | -5735 |
| NDUFB3 | -5630 |
| NDUFB8 | -5569 |
| NDUFS6 | -5537 |
| NDUFAF4 | -5432 |
| COX7C | -5326 |
| SCO1 | -5322 |
| COX4I1 | -5248 |
| NDUFB9 | -5052 |
| SCO2 | -4979 |
| COX19 | -4867 |
| COX16 | -4673 |
| COX14 | -4545 |
| ECSIT | -4451 |
| NDUFV1 | -4257 |
| COX6C | -4240 |
| TMEM186 | -4208 |
| NDUFS4 | -4157 |
| NDUFAF1 | -4070 |
| TIMMDC1 | -4054 |
| NDUFB1 | -4014 |
| NDUFV2 | -3987 |
| ACAD9 | -3714 |
| NDUFA7 | -3704 |
| COX11 | -3330 |
| TRAP1 | -3119 |
| NDUFB6 | -2896 |
| NDUFAF2 | -2788 |
| UQCRH | -2661 |
| NUBPL | -2171 |
| COQ10A | -1825 |
| COX7A2L | -1534 |
| NDUFAF6 | -1480 |
| ETFA | -1469 |
| NDUFA5 | -1323 |
| NDUFA12 | -1250 |
| MT-CO3 | -1115 |
| COX18 | -1013 |
| MT-CO2 | -988 |
| NDUFB5 | -429 |
| NDUFS1 | -297 |
| MT-ND4 | -94 |
| MT-ND2 | 425 |
| UQCRC2 | 468 |
| MT-CO1 | 720 |
| UQCRB | 1227 |
| NDUFAF7 | 1789 |
| COA1 | 1872 |
| MT-ND3 | 1944 |
| TMEM126B | 2158 |
| SDHD | 3003 |
| ETFDH | 3008 |
| NDUFS2 | 3010 |
| NDUFA9 | 3450 |
| NDUFA10 | 3483 |
| MT-ND1 | 3710 |
| LRPPRC | 4418 |
| MT-CYB | 5619 |
| CYCS | 7385 |
| NDUFAF5 | 7395 |
| COQ10B | 7585 |
| COX20 | 7745 |
FCERI mediated MAPK activation
| 381 | |
|---|---|
| set | FCERI mediated MAPK activation |
| setSize | 65 |
| pANOVA | 1.89e-13 |
| s.dist | -0.527 |
| p.adjustANOVA | 5.96e-12 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IGLV2-23 | -9156 |
| IGHV3-30 | -9155 |
| IGHV3-7 | -9140 |
| IGLV2-11 | -9139 |
| IGHV3-23 | -9138 |
| IGLV1-44 | -9132 |
| IGHV4-59 | -9129 |
| IGLC2 | -9127 |
| IGHV4-39 | -9126 |
| IGLV1-47 | -9125 |
| IGLV2-8 | -9121 |
| IGLC3 | -9120 |
| IGLV3-1 | -9116 |
| IGKV4-1 | -9113 |
| IGLV6-57 | -9112 |
| IGHV2-5 | -9098 |
| IGKC | -9087 |
| IGKV2-28 | -9071 |
| IGLV3-19 | -9065 |
| IGKV3-20 | -9057 |
| IGKV1-5 | -9049 |
| IGLC1 | -9006 |
| IGLV1-51 | -8998 |
| IGHV1-2 | -8953 |
| IGHV1-46 | -8910 |
| IGKV2D-28 | -8875 |
| IGKV3-11 | -8864 |
| IGKV1D-39 | -8828 |
| IGLV3-21 | -8806 |
| IGLV3-25 | -8773 |
| IGHV3-33 | -8608 |
| IGLV2-14 | -8572 |
| IGLV1-40 | -8088 |
| VAV1 | -7822 |
| MAP2K7 | -7697 |
| IGKV3-15 | -7403 |
| GRB2 | -7191 |
| IGHV3-11 | -7017 |
| MAPK3 | -6329 |
| SYK | -6217 |
| LCP2 | -5202 |
| HRAS | -4955 |
| IGKV1-33 | -4702 |
| LAT | -4104 |
| RAC1 | -3331 |
| PAK1 | -3309 |
| LYN | -2889 |
| VAV2 | -840 |
| MAP2K4 | 772 |
| MAPK1 | 1610 |
| NRAS | 1742 |
| GRAP2 | 1775 |
| VAV3 | 1970 |
| MAPK9 | 2439 |
| PAK2 | 2552 |
| MAP3K1 | 3619 |
| KRAS | 3903 |
| SHC1 | 4317 |
| SOS1 | 5452 |
| MAPK8 | 5565 |
| PLCG1 | 5830 |
| FOS | 8474 |
| PLCG2 | 8985 |
| JUN | 9573 |
| MAPK10 | 9718 |
Cellular responses to stress
| 181 | |
|---|---|
| set | Cellular responses to stress |
| setSize | 666 |
| pANOVA | 2.46e-13 |
| s.dist | -0.167 |
| p.adjustANOVA | 7.58e-12 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| NCF1 | -9092 |
| NUDT2 | -9056 |
| MAPK7 | -9047 |
| AKT1S1 | -9040 |
| CDKN2B | -9032 |
| HM13 | -9000 |
| IGFBP1 | -8984 |
| RPS26 | -8966 |
| RPA1 | -8931 |
| YIF1A | -8928 |
| MLST8 | -8926 |
| SOD3 | -8904 |
| KDELR3 | -8886 |
| CA9 | -8825 |
| P4HB | -8801 |
| MYDGF | -8769 |
| CARM1 | -8755 |
| CYBA | -8747 |
| NUP210 | -8727 |
| APOB | -8671 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| NCF1 | -9092 |
| NUDT2 | -9056 |
| MAPK7 | -9047 |
| AKT1S1 | -9040 |
| CDKN2B | -9032 |
| HM13 | -9000 |
| IGFBP1 | -8984 |
| RPS26 | -8966 |
| RPA1 | -8931 |
| YIF1A | -8928 |
| MLST8 | -8926 |
| SOD3 | -8904 |
| KDELR3 | -8886 |
| CA9 | -8825 |
| P4HB | -8801 |
| MYDGF | -8769 |
| CARM1 | -8755 |
| CYBA | -8747 |
| NUP210 | -8727 |
| APOB | -8671 |
| HYOU1 | -8670 |
| EXOSC4 | -8667 |
| SEC13 | -8653 |
| ATP6V0E2 | -8624 |
| TPP1 | -8589 |
| SURF1 | -8554 |
| NCOR2 | -8458 |
| ATP6V0C | -8415 |
| ATP6V1F | -8374 |
| HDGF | -8366 |
| KLHDC3 | -8362 |
| PSMD3 | -8328 |
| TLN1 | -8319 |
| CRTC1 | -8307 |
| COX8A | -8260 |
| TACO1 | -8234 |
| FKBP5 | -8210 |
| MAPKAPK3 | -8188 |
| GSK3A | -8163 |
| DCTN1 | -8155 |
| PSMD8 | -8149 |
| WDR24 | -8081 |
| CSNK2B | -8078 |
| RPA3 | -8040 |
| RPS4X | -8028 |
| SLC46A1 | -7928 |
| SRPRB | -7913 |
| POM121C | -7894 |
| TFDP2 | -7850 |
| HMGA1 | -7808 |
| KEAP1 | -7807 |
| RXRA | -7774 |
| TPR | -7773 |
| SRPRA | -7771 |
| PRDX2 | -7763 |
| CREB3 | -7757 |
| RPS19BP1 | -7740 |
| HSPA1L | -7723 |
| PSMB10 | -7709 |
| GPX1 | -7708 |
| DCTN3 | -7698 |
| MAP2K7 | -7697 |
| XBP1 | -7696 |
| GSTP1 | -7676 |
| EIF2AK1 | -7634 |
| SYVN1 | -7632 |
| PSMB5 | -7576 |
| HIRA | -7571 |
| GPX7 | -7527 |
| CUL7 | -7521 |
| KAT5 | -7497 |
| COX6B1 | -7448 |
| PTK6 | -7435 |
| VENTX | -7419 |
| DCTN5 | -7397 |
| ARFGAP1 | -7381 |
| LAMTOR1 | -7337 |
| DCTN2 | -7295 |
| PSME3 | -7280 |
| PSMB2 | -7268 |
| CDKN2A | -7189 |
| NUP62 | -7186 |
| COX6A1 | -7180 |
| CAPZB | -7174 |
| PSMD2 | -7104 |
| SOD1 | -7080 |
| PDIA6 | -7070 |
| ANAPC11 | -7053 |
| ATP6V0E1 | -7030 |
| HMOX2 | -7026 |
| AAAS | -7005 |
| BAG1 | -6939 |
| BLVRB | -6922 |
| PRKCD | -6909 |
| UBA52 | -6880 |
| TXN2 | -6874 |
| TCIRG1 | -6863 |
| COX5B | -6747 |
| COX5A | -6735 |
| PSMB6 | -6709 |
| SESN1 | -6704 |
| DYNLL2 | -6690 |
| CALR | -6689 |
| RPS6KA1 | -6676 |
| HSPA8 | -6665 |
| HERPUD1 | -6659 |
| NDUFA4 | -6655 |
| PSMB3 | -6647 |
| LAMTOR2 | -6641 |
| LAMTOR4 | -6618 |
| ELOB | -6600 |
| RRAGA | -6599 |
| HDAC3 | -6566 |
| DYNLL1 | -6465 |
| PSMD4 | -6452 |
| COX7B | -6445 |
| PRDX1 | -6420 |
| NUP88 | -6417 |
| NCF4 | -6412 |
| ATP6V0B | -6404 |
| RPL26L1 | -6364 |
| ACTR1A | -6346 |
| PSMF1 | -6332 |
| MAPK3 | -6329 |
| CBX6 | -6278 |
| MIOS | -6238 |
| POM121 | -6233 |
| H2BC12 | -6223 |
| GOSR2 | -6207 |
| NPRL3 | -6202 |
| UBB | -6193 |
| TXNRD2 | -6172 |
| PSMC5 | -6143 |
| ATP6V0D1 | -6117 |
| PSMA7 | -6082 |
| CRYAB | -6036 |
| TP53 | -6010 |
| TXNIP | -5982 |
| RAD50 | -5975 |
| PSMB7 | -5953 |
| EXOSC3 | -5942 |
| PSMC4 | -5866 |
| ITFG2 | -5814 |
| RPL39L | -5767 |
| ADD1 | -5751 |
| PPARA | -5728 |
| PSMC3 | -5726 |
| KHSRP | -5705 |
| MBTPS1 | -5686 |
| STIP1 | -5608 |
| H1-2 | -5529 |
| VCP | -5509 |
| PSMB1 | -5473 |
| DEDD2 | -5394 |
| TNFRSF21 | -5381 |
| EXOSC5 | -5349 |
| RPA2 | -5337 |
| NPRL2 | -5330 |
| NUP93 | -5327 |
| COX7C | -5326 |
| SCO1 | -5322 |
| PRDX6 | -5286 |
| ATOX1 | -5254 |
| COX4I1 | -5248 |
| RPS14 | -5234 |
| PHC2 | -5219 |
| CTDSP2 | -5213 |
| RPTOR | -5181 |
| PSMB4 | -5168 |
| NUP37 | -5152 |
| PLA2G4B | -5041 |
| TINF2 | -5009 |
| HIF1AN | -4992 |
| PREB | -4989 |
| SCO2 | -4979 |
| GPX8 | -4952 |
| ACADVL | -4950 |
| FKBP14 | -4925 |
| RPL27 | -4912 |
| RPL27A | -4896 |
| COX19 | -4867 |
| RPL35 | -4745 |
| SKP1 | -4737 |
| CRTC2 | -4734 |
| NUP188 | -4718 |
| LAMTOR5 | -4714 |
| COX16 | -4673 |
| RING1 | -4669 |
| CCAR2 | -4668 |
| CDK4 | -4665 |
| PSMD9 | -4655 |
| FAU | -4625 |
| BLVRA | -4615 |
| EXOSC6 | -4580 |
| NRIP1 | -4579 |
| COX14 | -4545 |
| DNAJB11 | -4537 |
| ATP6V1G1 | -4500 |
| RBX1 | -4435 |
| HMGA2 | -4425 |
| HSBP1 | -4424 |
| SEC31A | -4403 |
| HSPA5 | -4392 |
| DCTN6 | -4386 |
| ATP6V1D | -4357 |
| DYNC1H1 | -4355 |
| HSP90B1 | -4345 |
| ARNT | -4311 |
| HSPA2 | -4259 |
| PRDX5 | -4243 |
| COX6C | -4240 |
| WIPI1 | -4183 |
| PSMC2 | -4179 |
| RPL13 | -4148 |
| NFYC | -4144 |
| DNAJA4 | -4131 |
| TATDN2 | -4101 |
| RELA | -4097 |
| RPL8 | -4049 |
| RPS18 | -4032 |
| RPS10 | -4028 |
| GCN1 | -4027 |
| RPS29 | -4009 |
| EXOSC1 | -3990 |
| TERF2 | -3986 |
| RPS21 | -3873 |
| CYBB | -3854 |
| PSMD10 | -3849 |
| CREB3L4 | -3820 |
| HSF1 | -3763 |
| RPS5 | -3741 |
| ANAPC16 | -3739 |
| TRIB3 | -3731 |
| WFS1 | -3671 |
| SERP1 | -3659 |
| CDKN2C | -3607 |
| NUP214 | -3603 |
| BAG5 | -3596 |
| RPS11 | -3569 |
| RPL15 | -3543 |
| RPLP1 | -3524 |
| RPL36 | -3523 |
| RPL4 | -3472 |
| ANAPC2 | -3380 |
| H2BC5 | -3370 |
| RPL31 | -3359 |
| COX11 | -3330 |
| IMPACT | -3313 |
| RPL23 | -3274 |
| HDAC6 | -3228 |
| PSMA6 | -3225 |
| RPL10 | -3210 |
| H2AJ | -3209 |
| RPS25 | -3191 |
| RPL7A | -3188 |
| ATP6V1E1 | -3137 |
| MED1 | -3129 |
| RPL12 | -3105 |
| LY96 | -3104 |
| SSR1 | -3101 |
| TXNRD1 | -3072 |
| RPL29 | -3065 |
| RAE1 | -3056 |
| CDC26 | -3045 |
| RPS19 | -3032 |
| PSME1 | -3031 |
| NUP98 | -3024 |
| RPL30 | -3017 |
| TXN | -3012 |
| RPL19 | -2986 |
| RPS8 | -2974 |
| EGLN2 | -2959 |
| KPTN | -2883 |
| RPL35A | -2878 |
| RPLP0 | -2877 |
| ATF6 | -2851 |
| CREBBP | -2822 |
| EXOSC7 | -2747 |
| UBE2D2 | -2735 |
| PSMD7 | -2731 |
| RPL18 | -2728 |
| CCNE1 | -2722 |
| RPL18A | -2719 |
| CDKN2D | -2714 |
| EXOSC2 | -2713 |
| PPP2R5B | -2711 |
| RPL13A | -2708 |
| RPL38 | -2691 |
| RPS27 | -2657 |
| PSMA5 | -2649 |
| ATP6V1B2 | -2647 |
| PSMC1 | -2604 |
| MRPL18 | -2588 |
| HSPA12A | -2581 |
| RPS17 | -2555 |
| AR | -2536 |
| RPS23 | -2494 |
| RPS15 | -2484 |
| EHMT2 | -2459 |
| ANAPC7 | -2426 |
| YWHAE | -2405 |
| RPL34 | -2389 |
| FZR1 | -2354 |
| RPS3A | -2337 |
| RPL28 | -2326 |
| CRTC3 | -2295 |
| ASF1A | -2268 |
| RPLP2 | -2239 |
| TLR4 | -2238 |
| NUP85 | -2218 |
| STAT3 | -2208 |
| NCOR1 | -2161 |
| AGO1 | -2148 |
| PSMD14 | -2133 |
| RPL32 | -2131 |
| CCS | -2114 |
| RPL3L | -2091 |
| RPL23A | -2081 |
| RPS12 | -2076 |
| RPS15A | -2051 |
| MBTPS2 | -2040 |
| TFDP1 | -2011 |
| NDC1 | -1920 |
| EIF2AK4 | -1885 |
| LIMD1 | -1787 |
| PSMD1 | -1782 |
| RPL10A | -1766 |
| LAMTOR3 | -1758 |
| PSMA4 | -1756 |
| RPS20 | -1746 |
| RPL37A | -1736 |
| MAP2K3 | -1696 |
| RPS28 | -1692 |
| RPS3 | -1643 |
| FKBP4 | -1639 |
| EEF1A1 | -1605 |
| CXXC1 | -1602 |
| PSME2 | -1591 |
| RPS7 | -1576 |
| ANAPC10 | -1560 |
| COX7A2L | -1534 |
| RPL37 | -1517 |
| PSMD11 | -1483 |
| SULT1A3 | -1481 |
| DCSTAMP | -1446 |
| PSMD5 | -1433 |
| RPS24 | -1390 |
| E2F1 | -1381 |
| WDR59 | -1378 |
| SOD2 | -1375 |
| ANAPC5 | -1362 |
| NCF2 | -1349 |
| HSPA13 | -1326 |
| PSMA2 | -1286 |
| RPL3 | -1283 |
| GFPT1 | -1256 |
| RPS6 | -1245 |
| SIN3A | -1221 |
| GPX3 | -1215 |
| MAPK14 | -1200 |
| ANAPC15 | -1199 |
| CSNK2A1 | -1195 |
| MT-CO3 | -1115 |
| CDC23 | -1090 |
| SCMH1 | -1046 |
| RPL26 | -1044 |
| CHD9 | -1030 |
| COX18 | -1013 |
| MT-CO2 | -988 |
| ABCC1 | -953 |
| NCOA6 | -932 |
| RPL21 | -907 |
| ACD | -874 |
| RPL11 | -848 |
| RPL41 | -812 |
| CAPZA2 | -802 |
| PSMD13 | -754 |
| NUP205 | -738 |
| NR1D1 | -676 |
| EXTL3 | -649 |
| NUP42 | -641 |
| CREB3L2 | -632 |
| RPL17 | -614 |
| HIGD1A | -592 |
| MTOR | -561 |
| ZBTB17 | -554 |
| PARN | -498 |
| RPL6 | -483 |
| RPS16 | -451 |
| RPS2 | -411 |
| ACTR10 | -373 |
| RPL14 | -367 |
| UBN1 | -309 |
| FBXL17 | -292 |
| RPL24 | -289 |
| EP300 | -244 |
| PSMB8 | -235 |
| EIF2AK3 | -184 |
| PRDX3 | -171 |
| RPL5 | -160 |
| NUP153 | -156 |
| H2AZ1 | -91 |
| DNAJB6 | -83 |
| SMARCD3 | -65 |
| CABIN1 | -63 |
| PSME4 | -48 |
| CAMK2B | -37 |
| RBBP7 | -26 |
| RPS9 | 11 |
| PSMD6 | 26 |
| POT1 | 44 |
| DCTN4 | 48 |
| SP1 | 60 |
| ASNS | 108 |
| CSNK2A2 | 111 |
| BAG4 | 122 |
| RHEB | 132 |
| H2AC6 | 204 |
| RPS27L | 222 |
| RPS27A | 229 |
| FNIP2 | 295 |
| ATP6V1G2 | 311 |
| RRAGC | 329 |
| RPL22 | 345 |
| PSMA1 | 379 |
| RPL39 | 390 |
| H2BU1 | 397 |
| CAMK2A | 491 |
| NFKB1 | 503 |
| TBL1X | 506 |
| H2AZ2 | 509 |
| RPS4Y1 | 514 |
| BMT2 | 531 |
| CDC16 | 578 |
| SIN3B | 588 |
| VHL | 652 |
| MT-CO1 | 720 |
| MINK1 | 762 |
| EIF2S1 | 771 |
| MAP2K4 | 772 |
| EED | 800 |
| ATP6V1H | 924 |
| MAPKAPK2 | 933 |
| SERPINH1 | 960 |
| RPS13 | 1006 |
| ATM | 1033 |
| EHMT1 | 1068 |
| PTGES3 | 1088 |
| RBBP4 | 1093 |
| DNAJB9 | 1151 |
| DNAJC3 | 1382 |
| RRAGD | 1393 |
| CUL1 | 1406 |
| HSP90AB1 | 1424 |
| SZT2 | 1465 |
| EXTL2 | 1487 |
| UBE2E1 | 1544 |
| CHAC1 | 1568 |
| MAPK1 | 1610 |
| HSPA4 | 1668 |
| HSPA14 | 1688 |
| CCNA2 | 1702 |
| MAPKAPK5 | 1712 |
| CAPZA1 | 1732 |
| RPL7 | 1738 |
| PDIA5 | 1745 |
| UBE2C | 1747 |
| EP400 | 1767 |
| H2BC21 | 1774 |
| RB1 | 1797 |
| GSR | 1865 |
| DNAJC7 | 1919 |
| BMI1 | 1962 |
| ATP6V1A | 2025 |
| NR3C1 | 2034 |
| HIF3A | 2112 |
| NUP155 | 2114 |
| NUP35 | 2129 |
| H2AC18 | 2134 |
| MAP3K5 | 2141 |
| NUP54 | 2157 |
| TNIK | 2387 |
| MAPK9 | 2439 |
| RPS6KA2 | 2440 |
| NUP43 | 2453 |
| DDX11 | 2464 |
| NOX4 | 2465 |
| FLCN | 2571 |
| HSPA4L | 2574 |
| ST13 | 2595 |
| DYNC1LI2 | 2656 |
| RPL36A | 2688 |
| TGS1 | 2707 |
| E2F2 | 2726 |
| SESN2 | 2828 |
| ATP6V1C1 | 2865 |
| BACH1 | 2913 |
| RAI1 | 2960 |
| STAP2 | 2966 |
| CREBRF | 2996 |
| DNAJA2 | 3007 |
| TERF1 | 3026 |
| EIF2S2 | 3109 |
| ATP6V1E2 | 3118 |
| ID1 | 3145 |
| RANBP2 | 3171 |
| RPSA | 3175 |
| HSPA9 | 3176 |
| DYNC1I2 | 3198 |
| CLOCK | 3204 |
| ATF5 | 3227 |
| UBC | 3246 |
| ELOC | 3260 |
| CREB1 | 3370 |
| TNRC6C | 3379 |
| CITED2 | 3385 |
| ATP6V0D2 | 3413 |
| ERN1 | 3463 |
| CEBPB | 3467 |
| NCOA2 | 3470 |
| EXOSC8 | 3486 |
| BAG2 | 3549 |
| MOV10 | 3555 |
| ATP7A | 3594 |
| DCP2 | 3604 |
| EDEM1 | 3611 |
| DDIT3 | 3638 |
| CAT | 3646 |
| PSMD12 | 3658 |
| NUP133 | 3662 |
| EIF2S3 | 3667 |
| CUL2 | 3685 |
| HSP90AA1 | 3693 |
| UBE2D3 | 3753 |
| TERF2IP | 3798 |
| PSMC6 | 3801 |
| SLC38A9 | 3808 |
| NLRP3 | 3857 |
| RPS6KA3 | 3890 |
| CEBPG | 3920 |
| NCOA1 | 3941 |
| ATF2 | 3946 |
| SUZ12 | 3951 |
| RNF2 | 3972 |
| H3-3A | 4015 |
| NOX5 | 4104 |
| PSMB9 | 4121 |
| NBN | 4173 |
| HMOX1 | 4200 |
| ATF4 | 4212 |
| EZH2 | 4236 |
| SHC1 | 4317 |
| SEH1L | 4352 |
| PHC1 | 4367 |
| ANAPC1 | 4391 |
| LRPPRC | 4418 |
| CDC27 | 4464 |
| NUP58 | 4488 |
| HIKESHI | 4529 |
| CCNE2 | 4551 |
| CUL3 | 4595 |
| DIS3 | 4635 |
| ERO1A | 4711 |
| RPL36AL | 4730 |
| CBX4 | 4782 |
| DNAJA1 | 4799 |
| RPL9 | 4853 |
| E2F3 | 5003 |
| PGR | 5027 |
| PSMA3 | 5077 |
| RPL22L1 | 5078 |
| NUP160 | 5248 |
| MDM2 | 5371 |
| SEM1 | 5372 |
| UBE2S | 5380 |
| UBE2D1 | 5427 |
| HELZ2 | 5538 |
| MAFK | 5544 |
| MAPK8 | 5565 |
| GSK3B | 5609 |
| WTIP | 5680 |
| HBA1 | 5744 |
| NUP50 | 5758 |
| HBB | 5795 |
| RRAGB | 5856 |
| CBX2 | 5858 |
| MEF2D | 6088 |
| ATP6V1B1 | 6096 |
| PHC3 | 6121 |
| MAP2K6 | 6128 |
| CREB3L1 | 6131 |
| HSPH1 | 6134 |
| DNAJC2 | 6147 |
| CDK6 | 6175 |
| CAMK2G | 6254 |
| DYNC1LI1 | 6270 |
| DEPDC5 | 6304 |
| AGO4 | 6428 |
| TNRC6A | 6524 |
| TBL1XR1 | 6553 |
| PPARGC1A | 6593 |
| RORA | 6791 |
| AGO3 | 6796 |
| ANAPC4 | 6889 |
| MRE11 | 6908 |
| NR3C2 | 7022 |
| ATP6V1C2 | 7031 |
| EGLN1 | 7105 |
| FNIP1 | 7191 |
| CXCL8 | 7197 |
| EXOSC9 | 7206 |
| COL4A6 | 7219 |
| HIF1A | 7278 |
| TSPYL2 | 7327 |
| CYCS | 7385 |
| ERF | 7400 |
| HSPB8 | 7428 |
| TNRC6B | 7523 |
| HSPA12B | 7542 |
| NPAS2 | 7575 |
| LMNA | 7628 |
| LMNB1 | 7662 |
| DYNC1I1 | 7687 |
| COX20 | 7745 |
| SKP2 | 7870 |
| BAG3 | 7903 |
| H1-0 | 7919 |
| CDK2 | 8007 |
| CBX8 | 8025 |
| MEF2C | 8059 |
| XPO1 | 8102 |
| MDM4 | 8113 |
| NFYB | 8132 |
| NFYA | 8142 |
| SIRT1 | 8207 |
| EPAS1 | 8247 |
| AJUBA | 8282 |
| HSPA7 | 8400 |
| MAP4K4 | 8436 |
| FOS | 8474 |
| NFE2L2 | 8542 |
| CDKN1B | 8660 |
| HSPA6 | 8872 |
| ARNTL | 8892 |
| HSPA1B | 8917 |
| SH3BP4 | 9075 |
| GRB10 | 9089 |
| CAMK2D | 9106 |
| DNAJB1 | 9233 |
| NUP107 | 9235 |
| MAPK11 | 9361 |
| KDM6B | 9477 |
| EGLN3 | 9480 |
| ATR | 9507 |
| JUN | 9573 |
| VEGFA | 9645 |
| IGFBP7 | 9699 |
| MAPK10 | 9718 |
| ETS2 | 9750 |
| CCL2 | 9784 |
| CDKN1A | 9840 |
| IL6 | 9872 |
| ETS1 | 9885 |
| ATF3 | 9917 |
| HSPA1A | 9988 |
| PPP1R15A | 9997 |
Cellular response to chemical stress
| 176 | |
|---|---|
| set | Cellular response to chemical stress |
| setSize | 151 |
| pANOVA | 7.82e-13 |
| s.dist | -0.338 |
| p.adjustANOVA | 2.36e-11 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| NCF1 | -9092 |
| NUDT2 | -9056 |
| HM13 | -9000 |
| SOD3 | -8904 |
| P4HB | -8801 |
| CARM1 | -8755 |
| CYBA | -8747 |
| SURF1 | -8554 |
| NCOR2 | -8458 |
| PSMD3 | -8328 |
| COX8A | -8260 |
| TACO1 | -8234 |
| PSMD8 | -8149 |
| CSNK2B | -8078 |
| KEAP1 | -7807 |
| RXRA | -7774 |
| PRDX2 | -7763 |
| PSMB10 | -7709 |
| GPX1 | -7708 |
| GSTP1 | -7676 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| NCF1 | -9092 |
| NUDT2 | -9056 |
| HM13 | -9000 |
| SOD3 | -8904 |
| P4HB | -8801 |
| CARM1 | -8755 |
| CYBA | -8747 |
| SURF1 | -8554 |
| NCOR2 | -8458 |
| PSMD3 | -8328 |
| COX8A | -8260 |
| TACO1 | -8234 |
| PSMD8 | -8149 |
| CSNK2B | -8078 |
| KEAP1 | -7807 |
| RXRA | -7774 |
| PRDX2 | -7763 |
| PSMB10 | -7709 |
| GPX1 | -7708 |
| GSTP1 | -7676 |
| PSMB5 | -7576 |
| GPX7 | -7527 |
| COX6B1 | -7448 |
| PTK6 | -7435 |
| PSME3 | -7280 |
| PSMB2 | -7268 |
| COX6A1 | -7180 |
| PSMD2 | -7104 |
| SOD1 | -7080 |
| HMOX2 | -7026 |
| BLVRB | -6922 |
| PRKCD | -6909 |
| UBA52 | -6880 |
| TXN2 | -6874 |
| COX5B | -6747 |
| COX5A | -6735 |
| PSMB6 | -6709 |
| NDUFA4 | -6655 |
| PSMB3 | -6647 |
| HDAC3 | -6566 |
| PSMD4 | -6452 |
| COX7B | -6445 |
| PRDX1 | -6420 |
| NCF4 | -6412 |
| PSMF1 | -6332 |
| UBB | -6193 |
| TXNRD2 | -6172 |
| PSMC5 | -6143 |
| PSMA7 | -6082 |
| TXNIP | -5982 |
| PSMB7 | -5953 |
| PSMC4 | -5866 |
| PPARA | -5728 |
| PSMC3 | -5726 |
| PSMB1 | -5473 |
| COX7C | -5326 |
| SCO1 | -5322 |
| PRDX6 | -5286 |
| ATOX1 | -5254 |
| COX4I1 | -5248 |
| PSMB4 | -5168 |
| SCO2 | -4979 |
| GPX8 | -4952 |
| COX19 | -4867 |
| SKP1 | -4737 |
| COX16 | -4673 |
| PSMD9 | -4655 |
| BLVRA | -4615 |
| COX14 | -4545 |
| RBX1 | -4435 |
| PRDX5 | -4243 |
| COX6C | -4240 |
| PSMC2 | -4179 |
| CYBB | -3854 |
| PSMD10 | -3849 |
| COX11 | -3330 |
| PSMA6 | -3225 |
| MED1 | -3129 |
| TXNRD1 | -3072 |
| PSME1 | -3031 |
| TXN | -3012 |
| CREBBP | -2822 |
| PSMD7 | -2731 |
| PSMA5 | -2649 |
| PSMC1 | -2604 |
| STAT3 | -2208 |
| NCOR1 | -2161 |
| PSMD14 | -2133 |
| CCS | -2114 |
| PSMD1 | -1782 |
| PSMA4 | -1756 |
| PSME2 | -1591 |
| COX7A2L | -1534 |
| PSMD11 | -1483 |
| PSMD5 | -1433 |
| SOD2 | -1375 |
| NCF2 | -1349 |
| PSMA2 | -1286 |
| SIN3A | -1221 |
| GPX3 | -1215 |
| CSNK2A1 | -1195 |
| MT-CO3 | -1115 |
| CHD9 | -1030 |
| COX18 | -1013 |
| MT-CO2 | -988 |
| ABCC1 | -953 |
| NCOA6 | -932 |
| PSMD13 | -754 |
| FBXL17 | -292 |
| PSMB8 | -235 |
| PRDX3 | -171 |
| SMARCD3 | -65 |
| PSME4 | -48 |
| PSMD6 | 26 |
| CSNK2A2 | 111 |
| RPS27A | 229 |
| PSMA1 | 379 |
| TBL1X | 506 |
| SIN3B | 588 |
| MT-CO1 | 720 |
| CUL1 | 1406 |
| GSR | 1865 |
| NOX4 | 2465 |
| TGS1 | 2707 |
| BACH1 | 2913 |
| STAP2 | 2966 |
| UBC | 3246 |
| NCOA2 | 3470 |
| ATP7A | 3594 |
| CAT | 3646 |
| PSMD12 | 3658 |
| PSMC6 | 3801 |
| NLRP3 | 3857 |
| NCOA1 | 3941 |
| NOX5 | 4104 |
| PSMB9 | 4121 |
| HMOX1 | 4200 |
| LRPPRC | 4418 |
| CUL3 | 4595 |
| ERO1A | 4711 |
| PSMA3 | 5077 |
| SEM1 | 5372 |
| HELZ2 | 5538 |
| MAFK | 5544 |
| HBA1 | 5744 |
| HBB | 5795 |
| TBL1XR1 | 6553 |
| CYCS | 7385 |
| COX20 | 7745 |
| SKP2 | 7870 |
| NFE2L2 | 8542 |
Metabolism of amino acids and derivatives
| 667 | |
|---|---|
| set | Metabolism of amino acids and derivatives |
| setSize | 330 |
| pANOVA | 1.43e-12 |
| s.dist | -0.227 |
| p.adjustANOVA | 4.23e-11 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| CBS | -9158 |
| TSTD1 | -9111 |
| SERINC2 | -9058 |
| RPS26 | -8966 |
| PSPH | -8960 |
| ASS1 | -8829 |
| TST | -8714 |
| SLC6A12 | -8576 |
| GLUL | -8536 |
| PYCR1 | -8534 |
| NMRAL1 | -8476 |
| NNMT | -8371 |
| PSMD3 | -8328 |
| OGDH | -8244 |
| BCKDHA | -8203 |
| ALDH18A1 | -8160 |
| PSMD8 | -8149 |
| SARDH | -8137 |
| GLUD2 | -8102 |
| ECHS1 | -8052 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CBS | -9158 |
| TSTD1 | -9111 |
| SERINC2 | -9058 |
| RPS26 | -8966 |
| PSPH | -8960 |
| ASS1 | -8829 |
| TST | -8714 |
| SLC6A12 | -8576 |
| GLUL | -8536 |
| PYCR1 | -8534 |
| NMRAL1 | -8476 |
| NNMT | -8371 |
| PSMD3 | -8328 |
| OGDH | -8244 |
| BCKDHA | -8203 |
| ALDH18A1 | -8160 |
| PSMD8 | -8149 |
| SARDH | -8137 |
| GLUD2 | -8102 |
| ECHS1 | -8052 |
| SRM | -8050 |
| RPS4X | -8028 |
| FAH | -8016 |
| ETHE1 | -8012 |
| ALDH4A1 | -7836 |
| HSD17B10 | -7814 |
| PSMB10 | -7709 |
| PSMB5 | -7576 |
| OAZ1 | -7389 |
| SEPHS2 | -7373 |
| GPT2 | -7345 |
| PSME3 | -7280 |
| PSMB2 | -7268 |
| AMDHD1 | -7261 |
| GSTZ1 | -7252 |
| IL4I1 | -7228 |
| PSMD2 | -7104 |
| UBA52 | -6880 |
| TXN2 | -6874 |
| GAMT | -6862 |
| PSMB6 | -6709 |
| PSMB3 | -6647 |
| SRR | -6565 |
| ALDH9A1 | -6458 |
| PSMD4 | -6452 |
| SDSL | -6370 |
| RPL26L1 | -6364 |
| ADI1 | -6357 |
| AHCY | -6338 |
| PSMF1 | -6332 |
| BCAT1 | -6323 |
| PYCR2 | -6286 |
| QARS1 | -6159 |
| PSMC5 | -6143 |
| GPT | -6104 |
| AIMP2 | -6102 |
| QDPR | -6097 |
| PSMA7 | -6082 |
| GOT1 | -6071 |
| CKMT2 | -5993 |
| KYAT1 | -5966 |
| PSMB7 | -5953 |
| GCAT | -5929 |
| SDS | -5918 |
| SUOX | -5909 |
| NDUFAB1 | -5886 |
| PSMC4 | -5866 |
| RPL39L | -5767 |
| DDO | -5748 |
| GRHPR | -5743 |
| PSMC3 | -5726 |
| MARS1 | -5603 |
| PSMB1 | -5473 |
| TMLHE | -5466 |
| EEFSEC | -5462 |
| CKM | -5387 |
| RPS14 | -5234 |
| ACAD8 | -5218 |
| GOT2 | -5177 |
| PSMB4 | -5168 |
| HOGA1 | -5153 |
| LIPT1 | -5108 |
| PDHB | -5081 |
| GATM | -5079 |
| BCKDK | -5064 |
| MPST | -5050 |
| OAZ3 | -5046 |
| NAGS | -5010 |
| RPL27 | -4912 |
| RPL27A | -4896 |
| ALDH6A1 | -4889 |
| SLC6A8 | -4848 |
| BCAT2 | -4811 |
| DLST | -4766 |
| RPL35 | -4745 |
| HDC | -4735 |
| PSMD9 | -4655 |
| FAU | -4625 |
| PCBD1 | -4361 |
| IVD | -4350 |
| PAPSS2 | -4292 |
| PAPSS1 | -4246 |
| SLC36A4 | -4206 |
| EPRS1 | -4204 |
| PSMC2 | -4179 |
| CKB | -4151 |
| RPL13 | -4148 |
| RPL8 | -4049 |
| RPS18 | -4032 |
| RPS10 | -4028 |
| RPS29 | -4009 |
| HNMT | -3962 |
| GNMT | -3922 |
| RPS21 | -3873 |
| PSMD10 | -3849 |
| KARS1 | -3801 |
| MCCC2 | -3793 |
| PXMP2 | -3750 |
| RPS5 | -3741 |
| HIBADH | -3722 |
| SHMT1 | -3650 |
| RPS11 | -3569 |
| RPL15 | -3543 |
| OAT | -3533 |
| RPLP1 | -3524 |
| RPL36 | -3523 |
| IDO1 | -3496 |
| RPL4 | -3472 |
| RPL31 | -3359 |
| RPL23 | -3274 |
| GCDH | -3264 |
| PSMA6 | -3225 |
| RPL10 | -3210 |
| DUOX2 | -3207 |
| RPS25 | -3191 |
| RPL7A | -3188 |
| PAOX | -3185 |
| SARS1 | -3156 |
| RPL12 | -3105 |
| TXNRD1 | -3072 |
| RPL29 | -3065 |
| RPS19 | -3032 |
| PSME1 | -3031 |
| RPL30 | -3017 |
| RPL19 | -2986 |
| RPS8 | -2974 |
| GCSH | -2946 |
| CARNS1 | -2904 |
| RPL35A | -2878 |
| RPLP0 | -2877 |
| APIP | -2871 |
| PSMD7 | -2731 |
| RPL18 | -2728 |
| RPL18A | -2719 |
| RPL13A | -2708 |
| RPL38 | -2691 |
| RPS27 | -2657 |
| PSMA5 | -2649 |
| PSMC1 | -2604 |
| ADO | -2569 |
| RPS17 | -2555 |
| PDHA1 | -2529 |
| RPS23 | -2494 |
| RPS15 | -2484 |
| KYAT3 | -2462 |
| DIO3 | -2451 |
| PSAT1 | -2431 |
| RARS1 | -2420 |
| RIDA | -2410 |
| RPL34 | -2389 |
| KYNU | -2374 |
| RPS3A | -2337 |
| RPL28 | -2326 |
| SLC44A1 | -2325 |
| RPLP2 | -2239 |
| PSMD14 | -2133 |
| RPL32 | -2131 |
| CDO1 | -2123 |
| RPL3L | -2091 |
| RPL23A | -2081 |
| RPS12 | -2076 |
| RPS15A | -2051 |
| AGMAT | -1911 |
| PSMD1 | -1782 |
| RPL10A | -1766 |
| PSMA4 | -1756 |
| SCLY | -1751 |
| RPS20 | -1746 |
| RPL37A | -1736 |
| RPS28 | -1692 |
| RPS3 | -1643 |
| PSME2 | -1591 |
| RPS7 | -1576 |
| OAZ2 | -1550 |
| RPL37 | -1517 |
| PSMD11 | -1483 |
| HPD | -1438 |
| PSMD5 | -1433 |
| RPS24 | -1390 |
| NAT8L | -1332 |
| SERINC5 | -1298 |
| PSMA2 | -1286 |
| RPL3 | -1283 |
| KMO | -1276 |
| RPS6 | -1245 |
| TDO2 | -1225 |
| SLC25A21 | -1100 |
| RPL26 | -1044 |
| RPL21 | -907 |
| RPL11 | -848 |
| RPL41 | -812 |
| PSMD13 | -754 |
| EEF1E1 | -752 |
| GLUD1 | -728 |
| ARG2 | -723 |
| SLC25A10 | -722 |
| RPL17 | -614 |
| RPL6 | -483 |
| RPS16 | -451 |
| RPS2 | -411 |
| ASL | -391 |
| RPL14 | -367 |
| RPL24 | -289 |
| PSMB8 | -235 |
| ENOPH1 | -191 |
| RPL5 | -160 |
| SLC25A15 | -112 |
| PSME4 | -48 |
| PIPOX | -47 |
| RPS9 | 11 |
| PSMD6 | 26 |
| ASNS | 108 |
| SLC25A12 | 133 |
| AFMID | 197 |
| RPS27L | 222 |
| RPS27A | 229 |
| RPL22 | 345 |
| PSMA1 | 379 |
| RPL39 | 390 |
| DLAT | 403 |
| SLC3A2 | 494 |
| SERINC3 | 500 |
| RPS4Y1 | 514 |
| AZIN2 | 591 |
| PHYKPL | 649 |
| DMGDH | 804 |
| SERINC1 | 808 |
| CRYM | 898 |
| MRI1 | 918 |
| DCT | 995 |
| RPS13 | 1006 |
| SMS | 1140 |
| IARS1 | 1339 |
| CPS1 | 1442 |
| DUOX1 | 1484 |
| LIPT2 | 1515 |
| FTCD | 1617 |
| ACAT1 | 1619 |
| MTRR | 1643 |
| RPL7 | 1738 |
| GSR | 1865 |
| DIO2 | 1959 |
| PHGDH | 1999 |
| AIMP1 | 2228 |
| SLC25A44 | 2518 |
| DLD | 2572 |
| SMOX | 2647 |
| RPL36A | 2688 |
| DBT | 2950 |
| AUH | 3047 |
| HAAO | 3157 |
| RPSA | 3175 |
| MCCC1 | 3451 |
| CARNMT1 | 3543 |
| PSMD12 | 3658 |
| CSAD | 3713 |
| AZIN1 | 3763 |
| PSMC6 | 3801 |
| AMD1 | 3824 |
| PNMT | 3846 |
| DHTKD1 | 4065 |
| PSMB9 | 4121 |
| MTAP | 4167 |
| BHMT2 | 4226 |
| ALDH7A1 | 4408 |
| RPL36AL | 4730 |
| DARS1 | 4742 |
| PRODH | 4809 |
| RPL9 | 4853 |
| PDHX | 4872 |
| TPH1 | 4953 |
| AMT | 4989 |
| NAALAD2 | 5006 |
| PSMA3 | 5077 |
| RPL22L1 | 5078 |
| MTR | 5215 |
| SEM1 | 5372 |
| NQO1 | 5421 |
| SECISBP2 | 5536 |
| CHDH | 5661 |
| ASRGL1 | 5738 |
| SAT1 | 5910 |
| HIBCH | 5933 |
| LARS1 | 6001 |
| CTH | 6093 |
| CBSL | 6527 |
| PSTK | 6590 |
| HYKK | 6882 |
| GLS | 6907 |
| ACADSB | 6943 |
| LIAS | 7161 |
| SEPSECS | 7203 |
| RIMKLA | 7308 |
| GADL1 | 7360 |
| BCKDHB | 7513 |
| AASS | 7660 |
| FOLH1 | 7928 |
| AADAT | 8123 |
| INMT | 8160 |
| PPM1K | 8448 |
| ASPA | 8621 |
| SLC6A7 | 8645 |
| HAL | 8681 |
| GLDC | 8751 |
| SLC25A13 | 8791 |
| ODC1 | 9250 |
| TPH2 | 9428 |
| RIMKLB | 9588 |
| TPO | 9831 |
| SLC7A5 | 10071 |
Protein localization
| 899 | |
|---|---|
| set | Protein localization |
| setSize | 157 |
| pANOVA | 2.07e-12 |
| s.dist | -0.325 |
| p.adjustANOVA | 6.01e-11 |
Top enriched genes
| GeneID | Gene Rank |
|---|---|
| PEX6 | -9023 |
| ABCD1 | -8964 |
| CRAT | -8870 |
| ACO2 | -8665 |
| PEX10 | -8545 |
| CYC1 | -8353 |
| STX5 | -8241 |
| GFER | -8164 |
| PXMP4 | -8109 |
| PEX19 | -7860 |
| FIS1 | -7827 |
| STX1A | -7794 |
| HSCB | -7681 |
| CHCHD2 | -7598 |
| LDHD | -7558 |
| UBE2J2 | -7410 |
| BAG6 | -7364 |
| ATP5MC1 | -7251 |
| IDH3G | -7247 |
| TIMM13 | -7242 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| PEX6 | -9023 |
| ABCD1 | -8964 |
| CRAT | -8870 |
| ACO2 | -8665 |
| PEX10 | -8545 |
| CYC1 | -8353 |
| STX5 | -8241 |
| GFER | -8164 |
| PXMP4 | -8109 |
| PEX19 | -7860 |
| FIS1 | -7827 |
| STX1A | -7794 |
| HSCB | -7681 |
| CHCHD2 | -7598 |
| LDHD | -7558 |
| UBE2J2 | -7410 |
| BAG6 | -7364 |
| ATP5MC1 | -7251 |
| IDH3G | -7247 |
| TIMM13 | -7242 |
| TIMM17B | -7204 |
| SEC61B | -7068 |
| SGTA | -6983 |
| TIMM10 | -6956 |
| PEX11B | -6945 |
| OTOF | -6934 |
| UBA52 | -6880 |
| COX17 | -6843 |
| TOMM40 | -6803 |
| GET4 | -6776 |
| UBL4A | -6770 |
| TOMM6 | -6766 |
| ACOT8 | -6527 |
| CS | -6457 |
| PEX16 | -6441 |
| MPV17 | -6362 |
| TIMM22 | -6326 |
| SEC61G | -6251 |
| SAMM50 | -6246 |
| UBB | -6193 |
| VDAC1 | -6184 |
| TOMM5 | -6175 |
| TIMM8B | -6039 |
| ATP5F1A | -5919 |
| VAMP2 | -5893 |
| NOS2 | -5871 |
| COA4 | -5869 |
| TIMM21 | -5782 |
| DDO | -5748 |
| MTX1 | -5711 |
| NDUFB8 | -5569 |
| BCS1L | -5452 |
| CHCHD7 | -5386 |
| TIMM10B | -5385 |
| ACAA1 | -5304 |
| GET3 | -5268 |
| CHCHD5 | -5242 |
| APP | -5231 |
| ATP5F1B | -5140 |
| PEX2 | -5116 |
| PEX12 | -5023 |
| EPHX2 | -5019 |
| CHCHD10 | -4958 |
| SLC25A4 | -4920 |
| ALDH3A2 | -4906 |
| CMC4 | -4872 |
| COX19 | -4867 |
| PEX5 | -4860 |
| GRPEL1 | -4832 |
| HMGCL | -4696 |
| CHCHD4 | -4614 |
| PAM16 | -4176 |
| PRNP | -3900 |
| COA6 | -3766 |
| PXMP2 | -3750 |
| SERP1 | -3659 |
| ACOX2 | -3446 |
| IDH1 | -3258 |
| PMPCA | -3246 |
| COQ2 | -3231 |
| PAOX | -3185 |
| TIMM44 | -3165 |
| TYSND1 | -3121 |
| ABCD2 | -3051 |
| TIMM50 | -3016 |
| DHRS4 | -2914 |
| ACOX1 | -2912 |
| ECH1 | -2875 |
| UBE2D2 | -2735 |
| TIMM8A | -2596 |
| ECI2 | -2346 |
| HSD17B4 | -2299 |
| SLC25A6 | -2184 |
| GSTK1 | -2139 |
| CHCHD3 | -2082 |
| ACOT2 | -2003 |
| PEX14 | -1958 |
| ACOT4 | -1874 |
| PEX26 | -1797 |
| TIMM23 | -1788 |
| PEX7 | -1745 |
| TOMM22 | -1650 |
| DECR2 | -1601 |
| PECR | -1552 |
| TIMM17A | -1505 |
| TOMM70 | -1316 |
| TOMM7 | -1196 |
| ACOX3 | -1077 |
| USP9X | -962 |
| CROT | -850 |
| TAZ | -842 |
| MLYCD | -713 |
| NUDT19 | -689 |
| PIPOX | -47 |
| SLC25A12 | 133 |
| RPS27A | 229 |
| GNPAT | 297 |
| ATAD1 | 318 |
| ZFAND6 | 429 |
| CMC2 | 965 |
| PMPCB | 1040 |
| DNAJC19 | 1092 |
| TOMM20 | 1480 |
| AGPS | 1581 |
| EMD | 1663 |
| PHYH | 1705 |
| MTX2 | 1741 |
| TIMM9 | 2220 |
| AMACR | 2226 |
| SLC25A17 | 2290 |
| SCP2 | 2435 |
| FXN | 2807 |
| PEX1 | 2834 |
| CYB5A | 3159 |
| HSPA9 | 3176 |
| UBC | 3246 |
| HACL1 | 3285 |
| ABCD3 | 3362 |
| VAPA | 3437 |
| EHHADH | 3548 |
| LONP2 | 3561 |
| CAT | 3646 |
| NUDT7 | 3717 |
| UBE2D3 | 3753 |
| PITRM1 | 3856 |
| HMOX1 | 4200 |
| PEX13 | 4592 |
| UBE2D1 | 5427 |
| GDAP1 | 5848 |
| GET1 | 6400 |
| ACBD5 | 6530 |
| IDE | 6644 |
| CAMLG | 6731 |
| PEX3 | 7018 |
| HSPD1 | 7974 |
| GRPEL2 | 8165 |
| SLC25A13 | 8791 |
Here is the session info with all the versions of packages used.
sessionInfo()## R version 4.2.0 (2022-04-22)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 20.04.4 LTS
##
## Matrix products: default
## BLAS: /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.9.0
## LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.9.0
##
## locale:
## [1] LC_CTYPE=en_US.UTF-8 LC_NUMERIC=C
## [3] LC_TIME=en_US.UTF-8 LC_COLLATE=en_US.UTF-8
## [5] LC_MONETARY=en_US.UTF-8 LC_MESSAGES=en_US.UTF-8
## [7] LC_PAPER=en_US.UTF-8 LC_NAME=C
## [9] LC_ADDRESS=C LC_TELEPHONE=C
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C
##
## attached base packages:
## [1] parallel stats4 stats graphics grDevices utils datasets
## [8] methods base
##
## other attached packages:
## [1] pkgload_1.2.4 GGally_2.1.2
## [3] beeswarm_0.4.0 gtools_3.9.2
## [5] echarts4r_0.4.3 kableExtra_1.3.4
## [7] topconfects_1.8.0 limma_3.48.3
## [9] eulerr_6.1.1 mitch_1.4.1
## [11] MASS_7.3-56 fgsea_1.18.0
## [13] gplots_3.1.1 DESeq2_1.32.0
## [15] SummarizedExperiment_1.22.0 Biobase_2.52.0
## [17] MatrixGenerics_1.4.3 matrixStats_0.61.0
## [19] GenomicRanges_1.44.0 GenomeInfoDb_1.28.4
## [21] IRanges_2.26.0 S4Vectors_0.30.2
## [23] BiocGenerics_0.38.0 reshape2_1.4.4
## [25] forcats_0.5.1 stringr_1.4.0
## [27] dplyr_1.0.8 purrr_0.3.4
## [29] readr_2.1.2 tidyr_1.2.0
## [31] tibble_3.1.6 ggplot2_3.3.5
## [33] tidyverse_1.3.1 zoo_1.8-9
##
## loaded via a namespace (and not attached):
## [1] colorspace_2.0-3 ellipsis_0.3.2 rprojroot_2.0.2
## [4] XVector_0.32.0 fs_1.5.2 rstudioapi_0.13
## [7] bit64_4.0.5 AnnotationDbi_1.54.1 fansi_1.0.2
## [10] lubridate_1.8.0 xml2_1.3.3 splines_4.2.0
## [13] cachem_1.0.6 geneplotter_1.70.0 knitr_1.37
## [16] jsonlite_1.8.0 broom_0.7.12 annotate_1.70.0
## [19] dbplyr_2.1.1 png_0.1-7 shiny_1.7.1
## [22] compiler_4.2.0 httr_1.4.2 backports_1.4.1
## [25] assertthat_0.2.1 Matrix_1.4-1 fastmap_1.1.0
## [28] cli_3.2.0 later_1.3.0 htmltools_0.5.2
## [31] tools_4.2.0 gtable_0.3.0 glue_1.6.2
## [34] GenomeInfoDbData_1.2.6 fastmatch_1.1-3 Rcpp_1.0.8.2
## [37] cellranger_1.1.0 jquerylib_0.1.4 vctrs_0.3.8
## [40] Biostrings_2.60.2 svglite_2.1.0 xfun_0.30
## [43] rvest_1.0.2 mime_0.12 lifecycle_1.0.1
## [46] XML_3.99-0.9 zlibbioc_1.38.0 scales_1.1.1
## [49] promises_1.2.0.1 hms_1.1.1 RColorBrewer_1.1-2
## [52] yaml_2.3.5 gridExtra_2.3 memoise_2.0.1
## [55] sass_0.4.0 reshape_0.8.8 stringi_1.7.6
## [58] RSQLite_2.2.10 highr_0.9 genefilter_1.74.1
## [61] desc_1.4.1 caTools_1.18.2 BiocParallel_1.26.2
## [64] systemfonts_1.0.4 rlang_1.0.2 pkgconfig_2.0.3
## [67] bitops_1.0-7 evaluate_0.15 lattice_0.20-45
## [70] htmlwidgets_1.5.4 bit_4.0.4 tidyselect_1.1.2
## [73] plyr_1.8.6 magrittr_2.0.2 R6_2.5.1
## [76] generics_0.1.2 DelayedArray_0.18.0 DBI_1.1.2
## [79] pillar_1.7.0 haven_2.4.3 withr_2.5.0
## [82] survival_3.3-1 KEGGREST_1.32.0 RCurl_1.98-1.6
## [85] modelr_0.1.8 crayon_1.5.0 KernSmooth_2.23-20
## [88] utf8_1.2.2 tzdb_0.2.0 rmarkdown_2.13
## [91] locfit_1.5-9.5 grid_4.2.0 readxl_1.3.1
## [94] data.table_1.14.2 blob_1.2.2 webshot_0.5.2
## [97] reprex_2.0.1 digest_0.6.29 xtable_1.8-4
## [100] httpuv_1.6.5 munsell_0.5.0 viridisLite_0.4.0
## [103] bslib_0.3.1END of report