Mitch Report
Antony Kaspi & Mark Ziemann
date generated: 2024-01-18
Background
Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch
Input profiles
Here is the first few lines of the input profile.
| x | |
|---|---|
| A1BG | 0.0005615 |
| A1BG-AS1 | 0.0011225 |
| A1CF | 0.0008953 |
| A2M | 0.0001441 |
| A2M-AS1 | -0.0026319 |
| A2ML1 | -0.0005659 |
Here are some metrics about the input data profile:
| Profile metrics | |
|---|---|
| num_genesets | 1654 |
| num_genes_in_profile | 22007 |
| duplicated_genes_present | 0 |
| num_profile_genes_in_sets | 10383 |
| num_profile_genes_not_in_sets | 11624 |
Here is a plot of the input profiles. Note the dynamic ranges.
Here is the contour plot of the profile including all detected genes.
Input genesets
Here are some metrics about the gene sets used:
GMT file of genesets: c2.cp.reactome.v2023.1.Hs.symbols.gmt| Gene sets metrics | |
|---|---|
| num_genesets | 1654 |
| num_genesets_excluded | 365 |
| num_genesets_included | 1289 |
Differential pathway expression
Interactive enrichment scatterplot
Significance is calculated by -log10(p-value). All points shown are
FDR<0.05.
Significance is calculated by -log10(p-value). Top N sets shown
irrespective of FDR.
Results table
Top N= 50 gene sets
## Warning in kable_styling(., "hover", full_width = FALSE): Please specify format
## in kable. kableExtra can customize either HTML or LaTeX outputs. See
## https://haozhu233.github.io/kableExtra/ for details.| set | setSize | pANOVA | s.dist | p.adjustANOVA |
|---|---|---|---|---|
| REACTOME SIGNALING BY GPCR | 673 | 1.18e-06 | 0.1100 | 0.00108 |
| REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS | 312 | 1.32e-06 | 0.1590 | 0.00108 |
| REACTOME GPCR LIGAND BINDING | 444 | 2.98e-06 | 0.1290 | 0.00163 |
| REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | 55 | 3.08e-05 | 0.3250 | 0.01250 |
| REACTOME G ALPHA I SIGNALLING EVENTS | 304 | 3.81e-05 | 0.1370 | 0.01250 |
| REACTOME PEPTIDE LIGAND BINDING RECEPTORS | 188 | 9.22e-05 | 0.1650 | 0.02520 |
| REACTOME SENSORY PERCEPTION | 555 | 2.15e-04 | 0.0919 | 0.04800 |
| REACTOME NEUTROPHIL DEGRANULATION | 460 | 2.34e-04 | -0.1000 | 0.04800 |
| REACTOME OLFACTORY SIGNALING PATHWAY | 348 | 3.05e-04 | 0.1130 | 0.05570 |
| REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION | 1356 | 8.04e-04 | -0.0542 | 0.13200 |
| REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF | 53 | 1.20e-03 | -0.2570 | 0.17100 |
| REACTOME FATTY ACID METABOLISM | 170 | 1.25e-03 | -0.1430 | 0.17100 |
| REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER | 81 | 1.36e-03 | -0.2060 | 0.17200 |
| REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP | 41 | 1.60e-03 | -0.2850 | 0.18700 |
| REACTOME AMINE LIGAND BINDING RECEPTORS | 40 | 2.08e-03 | 0.2810 | 0.22700 |
| REACTOME INNATE IMMUNE SYSTEM | 1002 | 2.23e-03 | -0.0571 | 0.22800 |
| REACTOME PD 1 SIGNALING | 21 | 2.61e-03 | 0.3790 | 0.25200 |
| REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | 296 | 3.02e-03 | -0.1000 | 0.25200 |
| REACTOME MUSCLE CONTRACTION | 197 | 3.06e-03 | 0.1220 | 0.25200 |
| REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS | 53 | 3.07e-03 | -0.2350 | 0.25200 |
| REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION | 361 | 4.50e-03 | -0.0870 | 0.34200 |
| REACTOME GLUTATHIONE CONJUGATION | 33 | 4.58e-03 | -0.2850 | 0.34200 |
| REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC | 198 | 4.93e-03 | -0.1160 | 0.35200 |
| REACTOME NUCLEOTIDE EXCISION REPAIR | 107 | 5.80e-03 | -0.1540 | 0.39500 |
| REACTOME SODIUM CALCIUM EXCHANGERS | 11 | 6.01e-03 | 0.4780 | 0.39500 |
| REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | 18 | 8.57e-03 | 0.3580 | 0.54100 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES | 12 | 9.84e-03 | -0.4300 | 0.57000 |
| REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION | 19 | 9.89e-03 | -0.3420 | 0.57000 |
| REACTOME METABOLISM OF LIPIDS | 709 | 1.01e-02 | -0.0567 | 0.57000 |
| REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION | 26 | 1.08e-02 | -0.2890 | 0.59000 |
| REACTOME SUMO IS PROTEOLYTICALLY PROCESSED | 6 | 1.14e-02 | -0.5960 | 0.60400 |
| REACTOME STRIATED MUSCLE CONTRACTION | 35 | 1.18e-02 | 0.2460 | 0.60400 |
| REACTOME GLYCOGEN STORAGE DISEASES | 15 | 1.28e-02 | -0.3710 | 0.61100 |
| REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING | 12 | 1.28e-02 | -0.4150 | 0.61100 |
| REACTOME NEDDYLATION | 235 | 1.31e-02 | -0.0940 | 0.61100 |
| REACTOME NEURONAL SYSTEM | 388 | 1.37e-02 | 0.0729 | 0.61100 |
| REACTOME TRANS GOLGI NETWORK VESICLE BUDDING | 67 | 1.38e-02 | -0.1740 | 0.61100 |
| REACTOME GABA RECEPTOR ACTIVATION | 57 | 1.47e-02 | 0.1870 | 0.63600 |
| REACTOME INFLAMMASOMES | 21 | 1.55e-02 | -0.3050 | 0.65300 |
| REACTOME MITOTIC METAPHASE AND ANAPHASE | 228 | 1.62e-02 | -0.0924 | 0.65500 |
| REACTOME CA2 ACTIVATED K CHANNELS | 9 | 1.67e-02 | 0.4610 | 0.65500 |
| REACTOME VESICLE MEDIATED TRANSPORT | 642 | 1.68e-02 | -0.0553 | 0.65500 |
| REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS | 5 | 1.76e-02 | 0.6130 | 0.67300 |
| REACTOME GENERATION OF SECOND MESSENGER MOLECULES | 30 | 1.83e-02 | 0.2490 | 0.68200 |
| REACTOME GERM LAYER FORMATION AT GASTRULATION | 17 | 1.98e-02 | 0.3270 | 0.71800 |
| REACTOME MEMBRANE TRAFFICKING | 603 | 2.03e-02 | -0.0553 | 0.71800 |
| REACTOME ADRENOCEPTORS | 9 | 2.09e-02 | 0.4450 | 0.71800 |
| REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES | 27 | 2.10e-02 | -0.2570 | 0.71800 |
| REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS | 14 | 2.23e-02 | 0.3530 | 0.72400 |
| REACTOME DUAL INCISION IN GG NER | 39 | 2.24e-02 | -0.2110 | 0.72400 |
Results (complete table)
Click HERE to show results for all gene sets
| set | setSize | pANOVA | s.dist | p.adjustANOVA |
|---|---|---|---|---|
| REACTOME SIGNALING BY GPCR | 673 | 1.18e-06 | 1.10e-01 | 0.00108 |
| REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS | 312 | 1.32e-06 | 1.59e-01 | 0.00108 |
| REACTOME GPCR LIGAND BINDING | 444 | 2.98e-06 | 1.29e-01 | 0.00163 |
| REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | 55 | 3.08e-05 | 3.25e-01 | 0.01250 |
| REACTOME G ALPHA I SIGNALLING EVENTS | 304 | 3.81e-05 | 1.37e-01 | 0.01250 |
| REACTOME PEPTIDE LIGAND BINDING RECEPTORS | 188 | 9.22e-05 | 1.65e-01 | 0.02520 |
| REACTOME SENSORY PERCEPTION | 555 | 2.15e-04 | 9.19e-02 | 0.04800 |
| REACTOME NEUTROPHIL DEGRANULATION | 460 | 2.34e-04 | -1.00e-01 | 0.04800 |
| REACTOME OLFACTORY SIGNALING PATHWAY | 348 | 3.05e-04 | 1.13e-01 | 0.05570 |
| REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION | 1356 | 8.04e-04 | -5.42e-02 | 0.13200 |
| REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF | 53 | 1.20e-03 | -2.57e-01 | 0.17100 |
| REACTOME FATTY ACID METABOLISM | 170 | 1.25e-03 | -1.43e-01 | 0.17100 |
| REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER | 81 | 1.36e-03 | -2.06e-01 | 0.17200 |
| REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP | 41 | 1.60e-03 | -2.85e-01 | 0.18700 |
| REACTOME AMINE LIGAND BINDING RECEPTORS | 40 | 2.08e-03 | 2.81e-01 | 0.22700 |
| REACTOME INNATE IMMUNE SYSTEM | 1002 | 2.23e-03 | -5.71e-02 | 0.22800 |
| REACTOME PD 1 SIGNALING | 21 | 2.61e-03 | 3.79e-01 | 0.25200 |
| REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | 296 | 3.02e-03 | -1.00e-01 | 0.25200 |
| REACTOME MUSCLE CONTRACTION | 197 | 3.06e-03 | 1.22e-01 | 0.25200 |
| REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS | 53 | 3.07e-03 | -2.35e-01 | 0.25200 |
| REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION | 361 | 4.50e-03 | -8.70e-02 | 0.34200 |
| REACTOME GLUTATHIONE CONJUGATION | 33 | 4.58e-03 | -2.85e-01 | 0.34200 |
| REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC | 198 | 4.93e-03 | -1.16e-01 | 0.35200 |
| REACTOME NUCLEOTIDE EXCISION REPAIR | 107 | 5.80e-03 | -1.54e-01 | 0.39500 |
| REACTOME SODIUM CALCIUM EXCHANGERS | 11 | 6.01e-03 | 4.78e-01 | 0.39500 |
| REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | 18 | 8.57e-03 | 3.58e-01 | 0.54100 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES | 12 | 9.84e-03 | -4.30e-01 | 0.57000 |
| REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION | 19 | 9.89e-03 | -3.42e-01 | 0.57000 |
| REACTOME METABOLISM OF LIPIDS | 709 | 1.01e-02 | -5.67e-02 | 0.57000 |
| REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION | 26 | 1.08e-02 | -2.89e-01 | 0.59000 |
| REACTOME SUMO IS PROTEOLYTICALLY PROCESSED | 6 | 1.14e-02 | -5.96e-01 | 0.60400 |
| REACTOME STRIATED MUSCLE CONTRACTION | 35 | 1.18e-02 | 2.46e-01 | 0.60400 |
| REACTOME GLYCOGEN STORAGE DISEASES | 15 | 1.28e-02 | -3.71e-01 | 0.61100 |
| REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING | 12 | 1.28e-02 | -4.15e-01 | 0.61100 |
| REACTOME NEDDYLATION | 235 | 1.31e-02 | -9.40e-02 | 0.61100 |
| REACTOME NEURONAL SYSTEM | 388 | 1.37e-02 | 7.29e-02 | 0.61100 |
| REACTOME TRANS GOLGI NETWORK VESICLE BUDDING | 67 | 1.38e-02 | -1.74e-01 | 0.61100 |
| REACTOME GABA RECEPTOR ACTIVATION | 57 | 1.47e-02 | 1.87e-01 | 0.63600 |
| REACTOME INFLAMMASOMES | 21 | 1.55e-02 | -3.05e-01 | 0.65300 |
| REACTOME MITOTIC METAPHASE AND ANAPHASE | 228 | 1.62e-02 | -9.24e-02 | 0.65500 |
| REACTOME CA2 ACTIVATED K CHANNELS | 9 | 1.67e-02 | 4.61e-01 | 0.65500 |
| REACTOME VESICLE MEDIATED TRANSPORT | 642 | 1.68e-02 | -5.53e-02 | 0.65500 |
| REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS | 5 | 1.76e-02 | 6.13e-01 | 0.67300 |
| REACTOME GENERATION OF SECOND MESSENGER MOLECULES | 30 | 1.83e-02 | 2.49e-01 | 0.68200 |
| REACTOME GERM LAYER FORMATION AT GASTRULATION | 17 | 1.98e-02 | 3.27e-01 | 0.71800 |
| REACTOME MEMBRANE TRAFFICKING | 603 | 2.03e-02 | -5.53e-02 | 0.71800 |
| REACTOME ADRENOCEPTORS | 9 | 2.09e-02 | 4.45e-01 | 0.71800 |
| REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES | 27 | 2.10e-02 | -2.57e-01 | 0.71800 |
| REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS | 14 | 2.23e-02 | 3.53e-01 | 0.72400 |
| REACTOME DUAL INCISION IN GG NER | 39 | 2.24e-02 | -2.11e-01 | 0.72400 |
| REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | 134 | 2.31e-02 | 1.14e-01 | 0.72400 |
| REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | 31 | 2.35e-02 | -2.35e-01 | 0.72400 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH PI3K | 7 | 2.38e-02 | 4.93e-01 | 0.72400 |
| REACTOME FIBRONECTIN MATRIX FORMATION | 6 | 2.38e-02 | -5.33e-01 | 0.72400 |
| REACTOME LTC4 CYSLTR MEDIATED IL4 PRODUCTION | 6 | 2.44e-02 | -5.30e-01 | 0.73000 |
| REACTOME PEROXISOMAL LIPID METABOLISM | 28 | 2.58e-02 | -2.43e-01 | 0.75200 |
| REACTOME ADAPTIVE IMMUNE SYSTEM | 729 | 2.73e-02 | -4.80e-02 | 0.75200 |
| REACTOME SYNTHESIS OF PC | 27 | 2.77e-02 | -2.45e-01 | 0.75200 |
| REACTOME ANTIMICROBIAL PEPTIDES | 76 | 2.79e-02 | -1.46e-01 | 0.75200 |
| REACTOME FATTY ACYL COA BIOSYNTHESIS | 36 | 2.81e-02 | -2.11e-01 | 0.75200 |
| REACTOME CARDIAC CONDUCTION | 125 | 2.83e-02 | 1.14e-01 | 0.75200 |
| REACTOME ACTIVATION OF MATRIX METALLOPROTEINASES | 30 | 2.86e-02 | 2.31e-01 | 0.75200 |
| REACTOME INTRA GOLGI TRAFFIC | 43 | 2.89e-02 | -1.93e-01 | 0.75200 |
| REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES | 255 | 2.96e-02 | 7.91e-02 | 0.76000 |
| REACTOME RMTS METHYLATE HISTONE ARGININES | 72 | 3.01e-02 | 1.48e-01 | 0.76100 |
| REACTOME DISEASES OF MITOTIC CELL CYCLE | 37 | 3.17e-02 | -2.04e-01 | 0.77800 |
| REACTOME PROTEIN LOCALIZATION | 153 | 3.17e-02 | -1.01e-01 | 0.77800 |
| REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE | 93 | 3.25e-02 | -1.28e-01 | 0.78600 |
| REACTOME PROGRAMMED CELL DEATH | 204 | 3.35e-02 | -8.63e-02 | 0.79800 |
| REACTOME FORMATION OF INCISION COMPLEX IN GG NER | 40 | 3.49e-02 | -1.93e-01 | 0.80500 |
| REACTOME ION HOMEOSTASIS | 52 | 3.51e-02 | 1.69e-01 | 0.80500 |
| REACTOME EXTRACELLULAR MATRIX ORGANIZATION | 291 | 3.65e-02 | 7.13e-02 | 0.80500 |
| REACTOME NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION | 193 | 3.69e-02 | 8.71e-02 | 0.80500 |
| REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | 66 | 3.71e-02 | 1.48e-01 | 0.80500 |
| REACTOME NOD1 2 SIGNALING PATHWAY | 33 | 3.79e-02 | -2.09e-01 | 0.80500 |
| REACTOME MITOTIC SPINDLE CHECKPOINT | 109 | 3.79e-02 | -1.15e-01 | 0.80500 |
| REACTOME TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER | 76 | 3.82e-02 | -1.38e-01 | 0.80500 |
| REACTOME MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS | 7 | 3.82e-02 | 4.52e-01 | 0.80500 |
| REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS | 18 | 3.90e-02 | -2.81e-01 | 0.80800 |
| REACTOME AMYLOID FIBER FORMATION | 102 | 3.94e-02 | 1.18e-01 | 0.80800 |
| REACTOME SYNTHESIS OF PE | 13 | 4.01e-02 | -3.29e-01 | 0.81300 |
| REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES | 14 | 4.13e-02 | -3.15e-01 | 0.82700 |
| REACTOME TERMINATION OF TRANSLESION DNA SYNTHESIS | 32 | 4.20e-02 | -2.08e-01 | 0.82900 |
| REACTOME COSTIMULATION BY THE CD28 FAMILY | 64 | 4.28e-02 | 1.46e-01 | 0.82900 |
| REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | 51 | 4.35e-02 | -1.63e-01 | 0.82900 |
| REACTOME INTESTINAL ABSORPTION | 5 | 4.38e-02 | -5.20e-01 | 0.82900 |
| REACTOME VITAMINS | 6 | 4.46e-02 | 4.73e-01 | 0.82900 |
| REACTOME SUMO IS CONJUGATED TO E1 UBA2 SAE1 | 5 | 4.47e-02 | -5.18e-01 | 0.82900 |
| REACTOME ATTACHMENT OF GPI ANCHOR TO UPAR | 7 | 4.54e-02 | -4.37e-01 | 0.82900 |
| REACTOME AURKA ACTIVATION BY TPX2 | 69 | 4.55e-02 | -1.39e-01 | 0.82900 |
| REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES | 39 | 4.59e-02 | -1.85e-01 | 0.82900 |
| REACTOME RAC3 GTPASE CYCLE | 85 | 4.66e-02 | -1.25e-01 | 0.83200 |
| REACTOME SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA | 52 | 4.83e-02 | 1.58e-01 | 0.85300 |
| REACTOME DNA REPAIR | 321 | 4.95e-02 | -6.38e-02 | 0.85900 |
| REACTOME SEPARATION OF SISTER CHROMATIDS | 184 | 4.97e-02 | -8.39e-02 | 0.85900 |
| REACTOME FLT3 SIGNALING IN DISEASE | 28 | 5.03e-02 | -2.14e-01 | 0.86100 |
| REACTOME GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER | 25 | 5.18e-02 | -2.25e-01 | 0.86400 |
| REACTOME RAC2 GTPASE CYCLE | 81 | 5.20e-02 | -1.25e-01 | 0.86400 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN | 21 | 5.25e-02 | 2.44e-01 | 0.86400 |
| REACTOME RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK | 47 | 5.26e-02 | -1.63e-01 | 0.86400 |
| REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION | 23 | 5.33e-02 | 2.33e-01 | 0.86400 |
| REACTOME ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION | 28 | 5.37e-02 | 2.11e-01 | 0.86400 |
| REACTOME RHO GTPASES ACTIVATE NADPH OXIDASES | 21 | 5.54e-02 | -2.42e-01 | 0.88300 |
| REACTOME DOPAMINE RECEPTORS | 5 | 5.75e-02 | 4.90e-01 | 0.90400 |
| REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION | 62 | 5.78e-02 | 1.39e-01 | 0.90400 |
| REACTOME SARS COV 1 INFECTION | 136 | 5.85e-02 | -9.39e-02 | 0.90700 |
| REACTOME RUNX3 REGULATES WNT SIGNALING | 8 | 6.05e-02 | 3.83e-01 | 0.91500 |
| REACTOME AMINO ACIDS REGULATE MTORC1 | 53 | 6.08e-02 | -1.49e-01 | 0.91500 |
| REACTOME FORMATION OF AXIAL MESODERM | 14 | 6.13e-02 | 2.89e-01 | 0.91500 |
| REACTOME CELLULAR RESPONSES TO STIMULI | 779 | 6.20e-02 | -3.93e-02 | 0.91500 |
| REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | 20 | 6.22e-02 | -2.41e-01 | 0.91500 |
| REACTOME PRE NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM | 6 | 6.24e-02 | -4.39e-01 | 0.91500 |
| REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX | 85 | 6.33e-02 | 1.17e-01 | 0.92000 |
| REACTOME ASPARTATE AND ASPARAGINE METABOLISM | 11 | 6.39e-02 | -3.23e-01 | 0.92000 |
| REACTOME REDUCTION OF CYTOSOLIC CA LEVELS | 11 | 6.53e-02 | 3.21e-01 | 0.93300 |
| REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION | 68 | 6.70e-02 | 1.28e-01 | 0.94200 |
| REACTOME POTASSIUM CHANNELS | 102 | 6.85e-02 | 1.04e-01 | 0.94200 |
| REACTOME DIGESTION AND ABSORPTION | 22 | 6.86e-02 | -2.24e-01 | 0.94200 |
| REACTOME PLATELET AGGREGATION PLUG FORMATION | 39 | 6.90e-02 | 1.68e-01 | 0.94200 |
| REACTOME INSULIN PROCESSING | 24 | 6.94e-02 | 2.14e-01 | 0.94200 |
| REACTOME INFECTIOUS DISEASE | 910 | 6.99e-02 | -3.54e-02 | 0.94200 |
| REACTOME ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS | 17 | 7.00e-02 | -2.54e-01 | 0.94200 |
| REACTOME MRNA EDITING C TO U CONVERSION | 8 | 7.06e-02 | -3.69e-01 | 0.94300 |
| REACTOME SIGNALING BY MET | 78 | 7.14e-02 | -1.18e-01 | 0.94500 |
| REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY | 14 | 7.19e-02 | 2.78e-01 | 0.94500 |
| REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS | 28 | 7.45e-02 | 1.95e-01 | 0.94600 |
| REACTOME DNA DAMAGE BYPASS | 47 | 7.45e-02 | -1.50e-01 | 0.94600 |
| REACTOME BUDDING AND MATURATION OF HIV VIRION | 28 | 7.53e-02 | -1.94e-01 | 0.94600 |
| REACTOME RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX | 29 | 7.67e-02 | -1.90e-01 | 0.94600 |
| REACTOME MISMATCH REPAIR | 15 | 7.83e-02 | -2.63e-01 | 0.94600 |
| REACTOME METABOLISM OF STEROIDS | 150 | 7.87e-02 | -8.32e-02 | 0.94600 |
| REACTOME ANCHORING FIBRIL FORMATION | 13 | 7.94e-02 | 2.81e-01 | 0.94600 |
| REACTOME SARS COV INFECTIONS | 392 | 8.05e-02 | -5.14e-02 | 0.94600 |
| REACTOME DISSOLUTION OF FIBRIN CLOT | 13 | 8.12e-02 | -2.79e-01 | 0.94600 |
| REACTOME ESTABLISHMENT OF SISTER CHROMATID COHESION | 9 | 8.19e-02 | -3.35e-01 | 0.94600 |
| REACTOME TRANSPORT OF FATTY ACIDS | 8 | 8.35e-02 | 3.53e-01 | 0.94600 |
| REACTOME GASTRULATION | 49 | 8.36e-02 | 1.43e-01 | 0.94600 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES | 43 | 8.48e-02 | -1.52e-01 | 0.94600 |
| REACTOME VITAMIN B2 RIBOFLAVIN METABOLISM | 7 | 8.52e-02 | -3.76e-01 | 0.94600 |
| REACTOME TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE | 39 | 8.57e-02 | -1.59e-01 | 0.94600 |
| REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | 16 | 8.68e-02 | -2.47e-01 | 0.94600 |
| REACTOME HDR THROUGH HOMOLOGOUS RECOMBINATION HRR | 66 | 8.70e-02 | -1.22e-01 | 0.94600 |
| REACTOME GLYCOGEN SYNTHESIS | 13 | 8.79e-02 | -2.73e-01 | 0.94600 |
| REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS | 16 | 8.89e-02 | -2.46e-01 | 0.94600 |
| REACTOME INTERLEUKIN 10 SIGNALING | 43 | 8.92e-02 | 1.50e-01 | 0.94600 |
| REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE | 19 | 9.01e-02 | -2.25e-01 | 0.94600 |
| REACTOME HIV INFECTION | 223 | 9.06e-02 | -6.58e-02 | 0.94600 |
| REACTOME HYDROLYSIS OF LPC | 9 | 9.17e-02 | 3.25e-01 | 0.94600 |
| REACTOME PIWI INTERACTING RNA PIRNA BIOGENESIS | 29 | 9.17e-02 | 1.81e-01 | 0.94600 |
| REACTOME RNA POLYMERASE I PROMOTER ESCAPE | 83 | 9.19e-02 | 1.07e-01 | 0.94600 |
| REACTOME PHENYLALANINE AND TYROSINE METABOLISM | 11 | 9.19e-02 | -2.93e-01 | 0.94600 |
| REACTOME NGF INDEPENDANT TRKA ACTIVATION | 5 | 9.27e-02 | 4.34e-01 | 0.94600 |
| REACTOME ACTIVATION OF TRKA RECEPTORS | 6 | 9.28e-02 | 3.96e-01 | 0.94600 |
| REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | 101 | 9.42e-02 | 9.64e-02 | 0.94600 |
| REACTOME CILIUM ASSEMBLY | 190 | 9.44e-02 | -7.04e-02 | 0.94600 |
| REACTOME PROCESSING AND ACTIVATION OF SUMO | 10 | 9.49e-02 | -3.05e-01 | 0.94600 |
| REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | 36 | 9.51e-02 | -1.61e-01 | 0.94600 |
| REACTOME DUAL INCISION IN TC NER | 63 | 9.58e-02 | -1.21e-01 | 0.94600 |
| REACTOME THE NLRP3 INFLAMMASOME | 16 | 9.62e-02 | -2.40e-01 | 0.94600 |
| REACTOME HIV LIFE CYCLE | 145 | 9.62e-02 | -8.00e-02 | 0.94600 |
| REACTOME ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING | 9 | 9.63e-02 | 3.20e-01 | 0.94600 |
| REACTOME DISEASES OF CARBOHYDRATE METABOLISM | 31 | 9.78e-02 | -1.72e-01 | 0.94600 |
| REACTOME DNA DAMAGE RECOGNITION IN GG NER | 36 | 9.82e-02 | -1.59e-01 | 0.94600 |
| REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION | 31 | 9.96e-02 | -1.71e-01 | 0.94600 |
| REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | 12 | 1.01e-01 | 2.74e-01 | 0.94600 |
| REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE | 11 | 1.01e-01 | 2.86e-01 | 0.94600 |
| REACTOME PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR | 21 | 1.02e-01 | -2.06e-01 | 0.94600 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES | 8 | 1.03e-01 | -3.33e-01 | 0.94600 |
| REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3 | 59 | 1.03e-01 | 1.23e-01 | 0.94600 |
| REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS | 15 | 1.04e-01 | 2.42e-01 | 0.94600 |
| REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET | 8 | 1.04e-01 | -3.32e-01 | 0.94600 |
| REACTOME ACYL CHAIN REMODELING OF CL | 5 | 1.04e-01 | 4.19e-01 | 0.94600 |
| REACTOME CLEC7A INFLAMMASOME PATHWAY | 6 | 1.04e-01 | -3.83e-01 | 0.94600 |
| REACTOME P38MAPK EVENTS | 13 | 1.05e-01 | -2.60e-01 | 0.94600 |
| REACTOME CYTOSOLIC TRNA AMINOACYLATION | 22 | 1.05e-01 | -1.99e-01 | 0.94600 |
| REACTOME REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION | 84 | 1.06e-01 | -1.02e-01 | 0.94600 |
| REACTOME RHOBTB3 ATPASE CYCLE | 8 | 1.07e-01 | -3.29e-01 | 0.94600 |
| REACTOME INTERLEUKIN 18 SIGNALING | 8 | 1.08e-01 | 3.28e-01 | 0.94600 |
| REACTOME COPII MEDIATED VESICLE TRANSPORT | 66 | 1.09e-01 | -1.14e-01 | 0.94600 |
| REACTOME RELEASE OF HH NP FROM THE SECRETING CELL | 8 | 1.10e-01 | 3.27e-01 | 0.94600 |
| REACTOME GLYCEROPHOSPHOLIPID CATABOLISM | 7 | 1.10e-01 | -3.48e-01 | 0.94600 |
| REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION | 84 | 1.11e-01 | 1.01e-01 | 0.94600 |
| REACTOME REGULATION OF FZD BY UBIQUITINATION | 21 | 1.12e-01 | 2.01e-01 | 0.94600 |
| REACTOME DEUBIQUITINATION | 260 | 1.12e-01 | -5.72e-02 | 0.94600 |
| REACTOME GOLGI TO ER RETROGRADE TRANSPORT | 132 | 1.12e-01 | -8.00e-02 | 0.94600 |
| REACTOME PHENYLALANINE METABOLISM | 6 | 1.13e-01 | -3.74e-01 | 0.94600 |
| REACTOME REGULATION OF SIGNALING BY NODAL | 9 | 1.13e-01 | -3.05e-01 | 0.94600 |
| REACTOME BIOLOGICAL OXIDATIONS | 210 | 1.14e-01 | -6.33e-02 | 0.94600 |
| REACTOME HDMS DEMETHYLATE HISTONES | 40 | 1.15e-01 | 1.44e-01 | 0.94600 |
| REACTOME M PHASE | 398 | 1.15e-01 | -4.60e-02 | 0.94600 |
| REACTOME DEFECTIVE CHST3 CAUSES SEDCJD | 7 | 1.16e-01 | 3.43e-01 | 0.94600 |
| REACTOME CS DS DEGRADATION | 12 | 1.16e-01 | 2.62e-01 | 0.94600 |
| REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES | 78 | 1.16e-01 | -1.03e-01 | 0.94600 |
| REACTOME DNA METHYLATION | 58 | 1.16e-01 | 1.19e-01 | 0.94600 |
| REACTOME CELL CYCLE CHECKPOINTS | 284 | 1.17e-01 | -5.40e-02 | 0.94600 |
| REACTOME RAS SIGNALING DOWNSTREAM OF NF1 LOSS OF FUNCTION VARIANTS | 7 | 1.18e-01 | -3.41e-01 | 0.94600 |
| REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | 45 | 1.19e-01 | -1.34e-01 | 0.94600 |
| REACTOME SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS | 16 | 1.19e-01 | -2.25e-01 | 0.94600 |
| REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS | 8 | 1.20e-01 | 3.18e-01 | 0.94600 |
| REACTOME ORGANIC ANION TRANSPORT | 5 | 1.22e-01 | 4.00e-01 | 0.94600 |
| REACTOME SURFACTANT METABOLISM | 28 | 1.22e-01 | 1.69e-01 | 0.94600 |
| REACTOME SIGNALING BY FGFR1 IN DISEASE | 38 | 1.22e-01 | -1.45e-01 | 0.94600 |
| REACTOME SIGNALING BY RNF43 MUTANTS | 8 | 1.22e-01 | 3.15e-01 | 0.94600 |
| REACTOME GABA B RECEPTOR ACTIVATION | 43 | 1.23e-01 | 1.36e-01 | 0.94600 |
| REACTOME HCMV EARLY EVENTS | 128 | 1.24e-01 | 7.87e-02 | 0.94600 |
| REACTOME PROCESSING OF SMDT1 | 16 | 1.24e-01 | -2.22e-01 | 0.94600 |
| REACTOME RNA POLYMERASE II TRANSCRIPTION | 1336 | 1.25e-01 | 2.50e-02 | 0.94600 |
| REACTOME METABOLISM OF INGESTED SEMET SEC MESEC INTO H2SE | 7 | 1.25e-01 | 3.35e-01 | 0.94600 |
| REACTOME NGF STIMULATED TRANSCRIPTION | 38 | 1.25e-01 | 1.44e-01 | 0.94600 |
| REACTOME HUR ELAVL1 BINDS AND STABILIZES MRNA | 8 | 1.26e-01 | -3.13e-01 | 0.94600 |
| REACTOME CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT | 19 | 1.26e-01 | -2.03e-01 | 0.94600 |
| REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE | 277 | 1.27e-01 | -5.33e-02 | 0.94600 |
| REACTOME ASPARAGINE N LINKED GLYCOSYLATION | 299 | 1.27e-01 | -5.13e-02 | 0.94600 |
| REACTOME RECYCLING OF EIF2 GDP | 7 | 1.27e-01 | -3.33e-01 | 0.94600 |
| REACTOME SIGNALING BY NTRKS | 132 | 1.28e-01 | 7.67e-02 | 0.94600 |
| REACTOME SODIUM PROTON EXCHANGERS | 7 | 1.28e-01 | 3.32e-01 | 0.94600 |
| REACTOME MRNA EDITING | 10 | 1.28e-01 | -2.78e-01 | 0.94600 |
| REACTOME PLATELET CALCIUM HOMEOSTASIS | 27 | 1.30e-01 | 1.68e-01 | 0.94600 |
| REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3 | 679 | 1.30e-01 | -3.41e-02 | 0.94600 |
| REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE | 22 | 1.31e-01 | 1.86e-01 | 0.94600 |
| REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT | 222 | 1.31e-01 | 5.88e-02 | 0.94600 |
| REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | 93 | 1.31e-01 | 9.06e-02 | 0.94600 |
| REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | 91 | 1.32e-01 | -9.14e-02 | 0.94600 |
| REACTOME SIGNALING BY FLT3 ITD AND TKD MUTANTS | 16 | 1.32e-01 | -2.18e-01 | 0.94600 |
| REACTOME COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING | 32 | 1.32e-01 | 1.54e-01 | 0.94600 |
| REACTOME TRANSPORT OF NUCLEOTIDE SUGARS | 8 | 1.33e-01 | -3.06e-01 | 0.94600 |
| REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS | 6 | 1.34e-01 | -3.53e-01 | 0.94600 |
| REACTOME CHL1 INTERACTIONS | 9 | 1.35e-01 | -2.88e-01 | 0.94600 |
| REACTOME TRANSCRIPTIONAL REGULATION BY TP53 | 351 | 1.35e-01 | -4.65e-02 | 0.94600 |
| REACTOME BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS | 10 | 1.35e-01 | -2.73e-01 | 0.94600 |
| REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION | 98 | 1.36e-01 | 8.72e-02 | 0.94600 |
| REACTOME PROTEIN UBIQUITINATION | 76 | 1.36e-01 | -9.88e-02 | 0.94600 |
| REACTOME INTERLEUKIN 6 SIGNALING | 11 | 1.37e-01 | -2.59e-01 | 0.94600 |
| REACTOME BETA DEFENSINS | 27 | 1.38e-01 | 1.65e-01 | 0.94600 |
| REACTOME RHO GTPASE EFFECTORS | 305 | 1.38e-01 | -4.93e-02 | 0.94600 |
| REACTOME MEIOTIC SYNAPSIS | 73 | 1.39e-01 | 1.00e-01 | 0.94600 |
| REACTOME ACTIVATION OF AMPK DOWNSTREAM OF NMDARS | 28 | 1.39e-01 | 1.62e-01 | 0.94600 |
| REACTOME GENE SILENCING BY RNA | 133 | 1.42e-01 | 7.38e-02 | 0.94600 |
| REACTOME APOPTOSIS | 173 | 1.43e-01 | -6.46e-02 | 0.94600 |
| REACTOME XENOBIOTICS | 22 | 1.45e-01 | -1.80e-01 | 0.94600 |
| REACTOME SPHINGOLIPID METABOLISM | 84 | 1.45e-01 | -9.19e-02 | 0.94600 |
| REACTOME SIGNALING BY NOTCH1 T 7 9 NOTCH1 M1580 K2555 TRANSLOCATION MUTANT | 7 | 1.45e-01 | 3.18e-01 | 0.94600 |
| REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | 160 | 1.46e-01 | -6.66e-02 | 0.94600 |
| REACTOME SIGNALING BY FLT3 FUSION PROTEINS | 19 | 1.46e-01 | -1.93e-01 | 0.94600 |
| REACTOME REGULATION OF RAS BY GAPS | 66 | 1.46e-01 | -1.03e-01 | 0.94600 |
| REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE | 63 | 1.47e-01 | 1.06e-01 | 0.94600 |
| REACTOME LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS | 19 | 1.48e-01 | -1.92e-01 | 0.94600 |
| REACTOME EARLY PHASE OF HIV LIFE CYCLE | 14 | 1.48e-01 | -2.23e-01 | 0.94600 |
| REACTOME MITOCHONDRIAL CALCIUM ION TRANSPORT | 23 | 1.48e-01 | -1.74e-01 | 0.94600 |
| REACTOME MET ACTIVATES PTPN11 | 5 | 1.48e-01 | 3.74e-01 | 0.94600 |
| REACTOME INTERLEUKIN 9 SIGNALING | 7 | 1.48e-01 | -3.16e-01 | 0.94600 |
| REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING | 25 | 1.48e-01 | 1.67e-01 | 0.94600 |
| REACTOME CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN | 45 | 1.49e-01 | -1.24e-01 | 0.94600 |
| REACTOME REGULATION OF RUNX1 EXPRESSION AND ACTIVITY | 17 | 1.49e-01 | -2.02e-01 | 0.94600 |
| REACTOME ER TO GOLGI ANTEROGRADE TRANSPORT | 152 | 1.49e-01 | -6.77e-02 | 0.94600 |
| REACTOME SIGNAL ATTENUATION | 10 | 1.50e-01 | 2.63e-01 | 0.94600 |
| REACTOME AMINO ACID CONJUGATION | 9 | 1.52e-01 | -2.76e-01 | 0.94600 |
| REACTOME EPHA MEDIATED GROWTH CONE COLLAPSE | 29 | 1.52e-01 | 1.54e-01 | 0.94600 |
| REACTOME MISCELLANEOUS TRANSPORT AND BINDING EVENTS | 24 | 1.52e-01 | -1.69e-01 | 0.94600 |
| REACTOME UPTAKE OF DIETARY COBALAMINS INTO ENTEROCYTES | 9 | 1.52e-01 | 2.76e-01 | 0.94600 |
| REACTOME REGULATION OF IFNA IFNB SIGNALING | 23 | 1.52e-01 | 1.72e-01 | 0.94600 |
| REACTOME SENSORY PERCEPTION OF SALTY TASTE | 6 | 1.54e-01 | -3.36e-01 | 0.94600 |
| REACTOME TRANSCRIPTIONAL REGULATION BY VENTX | 41 | 1.55e-01 | -1.28e-01 | 0.94600 |
| REACTOME STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS | 10 | 1.56e-01 | -2.59e-01 | 0.94600 |
| REACTOME CIRCADIAN CLOCK | 68 | 1.57e-01 | -9.92e-02 | 0.94600 |
| REACTOME LIGAND RECEPTOR INTERACTIONS | 8 | 1.58e-01 | 2.88e-01 | 0.94600 |
| REACTOME SIGNALING BY MST1 | 5 | 1.58e-01 | -3.64e-01 | 0.94600 |
| REACTOME PRC2 METHYLATES HISTONES AND DNA | 65 | 1.59e-01 | 1.01e-01 | 0.94600 |
| REACTOME FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES | 29 | 1.59e-01 | 1.51e-01 | 0.94600 |
| REACTOME RAC1 GTPASE CYCLE | 172 | 1.60e-01 | -6.21e-02 | 0.94600 |
| REACTOME REGULATION OF KIT SIGNALING | 16 | 1.60e-01 | 2.03e-01 | 0.94600 |
| REACTOME SIGNALING BY WNT | 318 | 1.61e-01 | 4.57e-02 | 0.94600 |
| REACTOME PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS | 7 | 1.61e-01 | -3.06e-01 | 0.94600 |
| REACTOME CELL CYCLE MITOTIC | 539 | 1.62e-01 | -3.52e-02 | 0.94600 |
| REACTOME SENSORY PROCESSING OF SOUND | 72 | 1.62e-01 | 9.53e-02 | 0.94600 |
| REACTOME RHO GTPASES ACTIVATE FORMINS | 136 | 1.63e-01 | -6.93e-02 | 0.94600 |
| REACTOME RNA POLYMERASE I TRANSCRIPTION | 102 | 1.64e-01 | 7.98e-02 | 0.94600 |
| REACTOME RHOU GTPASE CYCLE | 37 | 1.64e-01 | -1.32e-01 | 0.94600 |
| REACTOME RESOLUTION OF SISTER CHROMATID COHESION | 120 | 1.65e-01 | -7.35e-02 | 0.94600 |
| REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | 53 | 1.66e-01 | 1.10e-01 | 0.94600 |
| REACTOME BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA | 17 | 1.66e-01 | 1.94e-01 | 0.94600 |
| REACTOME STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES | 16 | 1.67e-01 | -2.00e-01 | 0.94600 |
| REACTOME HOST INTERACTIONS OF HIV FACTORS | 127 | 1.69e-01 | -7.07e-02 | 0.94600 |
| REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | 24 | 1.69e-01 | -1.62e-01 | 0.94600 |
| REACTOME HEME SIGNALING | 47 | 1.69e-01 | -1.16e-01 | 0.94600 |
| REACTOME LIPOPHAGY | 9 | 1.69e-01 | 2.65e-01 | 0.94600 |
| REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | 263 | 1.70e-01 | -4.91e-02 | 0.94600 |
| REACTOME CELL CYCLE | 666 | 1.70e-01 | -3.12e-02 | 0.94600 |
| REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | 8 | 1.70e-01 | 2.80e-01 | 0.94600 |
| REACTOME TRANSPORT OF SMALL MOLECULES | 697 | 1.71e-01 | 3.04e-02 | 0.94600 |
| REACTOME INTERLEUKIN 36 PATHWAY | 7 | 1.72e-01 | 2.98e-01 | 0.94600 |
| REACTOME COLLAGEN FORMATION | 88 | 1.72e-01 | 8.42e-02 | 0.94600 |
| REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | 129 | 1.74e-01 | -6.93e-02 | 0.94600 |
| REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY | 25 | 1.76e-01 | -1.56e-01 | 0.94600 |
| REACTOME FCERI MEDIATED CA 2 MOBILIZATION | 30 | 1.77e-01 | 1.42e-01 | 0.94600 |
| REACTOME LYSOSOME VESICLE BIOGENESIS | 33 | 1.78e-01 | -1.36e-01 | 0.94600 |
| REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS | 81 | 1.78e-01 | 8.67e-02 | 0.94600 |
| REACTOME MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS | 17 | 1.79e-01 | 1.88e-01 | 0.94600 |
| REACTOME INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE | 20 | 1.79e-01 | -1.74e-01 | 0.94600 |
| REACTOME GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | 34 | 1.79e-01 | 1.33e-01 | 0.94600 |
| REACTOME CHOLESTEROL BIOSYNTHESIS | 25 | 1.80e-01 | -1.55e-01 | 0.94600 |
| REACTOME KEAP1 NFE2L2 PATHWAY | 104 | 1.80e-01 | -7.61e-02 | 0.94600 |
| REACTOME SIGNALING BY WNT IN CANCER | 32 | 1.80e-01 | 1.37e-01 | 0.94600 |
| REACTOME MET ACTIVATES PI3K AKT SIGNALING | 6 | 1.82e-01 | 3.15e-01 | 0.94600 |
| REACTOME INTERLEUKIN 20 FAMILY SIGNALING | 25 | 1.82e-01 | -1.54e-01 | 0.94600 |
| REACTOME IRS ACTIVATION | 5 | 1.82e-01 | 3.45e-01 | 0.94600 |
| REACTOME MITOTIC PROMETAPHASE | 194 | 1.82e-01 | -5.55e-02 | 0.94600 |
| REACTOME RHO GTPASES ACTIVATE KTN1 | 11 | 1.83e-01 | -2.32e-01 | 0.94600 |
| REACTOME DEFENSINS | 33 | 1.83e-01 | 1.34e-01 | 0.94600 |
| REACTOME DISEASES OF METABOLISM | 237 | 1.83e-01 | -5.02e-02 | 0.94600 |
| REACTOME LDL CLEARANCE | 19 | 1.83e-01 | 1.76e-01 | 0.94600 |
| REACTOME DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1 | 9 | 1.84e-01 | -2.56e-01 | 0.94600 |
| REACTOME ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA | 9 | 1.86e-01 | -2.54e-01 | 0.94600 |
| REACTOME AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS | 9 | 1.87e-01 | 2.54e-01 | 0.94600 |
| REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION | 60 | 1.87e-01 | 9.85e-02 | 0.94600 |
| REACTOME ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS | 7 | 1.88e-01 | -2.87e-01 | 0.94600 |
| REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | 118 | 1.89e-01 | 7.01e-02 | 0.94600 |
| REACTOME PROTEIN METHYLATION | 17 | 1.89e-01 | -1.84e-01 | 0.94600 |
| REACTOME RESPONSE OF MTB TO PHAGOCYTOSIS | 22 | 1.89e-01 | -1.62e-01 | 0.94600 |
| REACTOME ALPHA OXIDATION OF PHYTANATE | 6 | 1.89e-01 | -3.10e-01 | 0.94600 |
| REACTOME CD209 DC SIGN SIGNALING | 20 | 1.89e-01 | -1.70e-01 | 0.94600 |
| REACTOME HEME BIOSYNTHESIS | 13 | 1.89e-01 | -2.10e-01 | 0.94600 |
| REACTOME IRE1ALPHA ACTIVATES CHAPERONES | 48 | 1.89e-01 | -1.10e-01 | 0.94600 |
| REACTOME BETA CATENIN PHOSPHORYLATION CASCADE | 16 | 1.91e-01 | -1.89e-01 | 0.94600 |
| REACTOME VISUAL PHOTOTRANSDUCTION | 93 | 1.91e-01 | 7.84e-02 | 0.94600 |
| REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | 7 | 1.93e-01 | 2.84e-01 | 0.94600 |
| REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | 11 | 1.94e-01 | 2.26e-01 | 0.94600 |
| REACTOME BINDING OF TCF LEF CTNNB1 TO TARGET GENE PROMOTERS | 8 | 1.94e-01 | 2.65e-01 | 0.94600 |
| REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | 183 | 1.95e-01 | -5.56e-02 | 0.94600 |
| REACTOME ERYTHROPOIETIN ACTIVATES STAT5 | 7 | 1.95e-01 | -2.83e-01 | 0.94600 |
| REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX | 21 | 1.96e-01 | -1.63e-01 | 0.94600 |
| REACTOME PHOSPHORYLATION OF THE APC C | 20 | 1.96e-01 | -1.67e-01 | 0.94600 |
| REACTOME PHASE II CONJUGATION OF COMPOUNDS | 102 | 1.97e-01 | -7.40e-02 | 0.94600 |
| REACTOME METABOLISM OF CARBOHYDRATES | 279 | 1.98e-01 | -4.48e-02 | 0.94600 |
| REACTOME SIGNALING BY NUCLEAR RECEPTORS | 283 | 1.98e-01 | 4.45e-02 | 0.94600 |
| REACTOME ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS | 20 | 1.98e-01 | -1.66e-01 | 0.94600 |
| REACTOME DEFECTIVE LFNG CAUSES SCDO3 | 5 | 1.99e-01 | -3.32e-01 | 0.94600 |
| REACTOME DRUG MEDIATED INHIBITION OF CDK4 CDK6 ACTIVITY | 5 | 1.99e-01 | -3.32e-01 | 0.94600 |
| REACTOME RESOLUTION OF ABASIC SITES AP SITES | 38 | 2.00e-01 | -1.20e-01 | 0.94600 |
| REACTOME INFECTION WITH MYCOBACTERIUM TUBERCULOSIS | 25 | 2.02e-01 | -1.47e-01 | 0.94600 |
| REACTOME CYCLIN D ASSOCIATED EVENTS IN G1 | 46 | 2.04e-01 | -1.08e-01 | 0.94600 |
| REACTOME TYPE I HEMIDESMOSOME ASSEMBLY | 11 | 2.04e-01 | 2.21e-01 | 0.94600 |
| REACTOME MELANIN BIOSYNTHESIS | 5 | 2.05e-01 | -3.28e-01 | 0.94600 |
| REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | 80 | 2.05e-01 | -8.20e-02 | 0.94600 |
| REACTOME TRANSCRIPTIONAL REGULATION BY MECP2 | 60 | 2.07e-01 | 9.42e-02 | 0.94600 |
| REACTOME ACTIVATION OF BH3 ONLY PROTEINS | 30 | 2.08e-01 | -1.33e-01 | 0.94600 |
| REACTOME PROLACTIN RECEPTOR SIGNALING | 15 | 2.09e-01 | -1.87e-01 | 0.94600 |
| REACTOME COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC | 98 | 2.09e-01 | -7.34e-02 | 0.94600 |
| REACTOME TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX | 10 | 2.09e-01 | -2.29e-01 | 0.94600 |
| REACTOME TRIGLYCERIDE CATABOLISM | 23 | 2.09e-01 | 1.51e-01 | 0.94600 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH RAS | 9 | 2.09e-01 | 2.42e-01 | 0.94600 |
| REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT | 236 | 2.09e-01 | 4.74e-02 | 0.94600 |
| REACTOME RHOG GTPASE CYCLE | 71 | 2.10e-01 | -8.61e-02 | 0.94600 |
| REACTOME TRP CHANNELS | 27 | 2.10e-01 | 1.39e-01 | 0.94600 |
| REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS | 63 | 2.12e-01 | 9.09e-02 | 0.94600 |
| REACTOME INTRAFLAGELLAR TRANSPORT | 50 | 2.12e-01 | -1.02e-01 | 0.94600 |
| REACTOME INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION | 21 | 2.13e-01 | -1.57e-01 | 0.94600 |
| REACTOME PP2A MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS | 6 | 2.13e-01 | -2.94e-01 | 0.94600 |
| REACTOME GLUCURONIDATION | 23 | 2.13e-01 | 1.50e-01 | 0.94600 |
| REACTOME HSF1 ACTIVATION | 29 | 2.14e-01 | -1.33e-01 | 0.94600 |
| REACTOME OTHER SEMAPHORIN INTERACTIONS | 18 | 2.14e-01 | 1.69e-01 | 0.94600 |
| REACTOME CONJUGATION OF BENZOATE WITH GLYCINE | 6 | 2.14e-01 | -2.93e-01 | 0.94600 |
| REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | 30 | 2.14e-01 | 1.31e-01 | 0.94600 |
| REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE | 52 | 2.14e-01 | 9.95e-02 | 0.94600 |
| REACTOME INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS | 37 | 2.15e-01 | -1.18e-01 | 0.94600 |
| REACTOME DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE | 76 | 2.15e-01 | 8.22e-02 | 0.94600 |
| REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS | 188 | 2.16e-01 | -5.24e-02 | 0.94600 |
| REACTOME RAP1 SIGNALLING | 16 | 2.17e-01 | -1.78e-01 | 0.94600 |
| REACTOME HEDGEHOG OFF STATE | 111 | 2.18e-01 | -6.77e-02 | 0.94600 |
| REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION | 90 | 2.18e-01 | 7.50e-02 | 0.94600 |
| REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK | 17 | 2.19e-01 | 1.72e-01 | 0.94600 |
| REACTOME DISEASES OF MISMATCH REPAIR MMR | 5 | 2.19e-01 | -3.17e-01 | 0.94600 |
| REACTOME METABOLISM OF FAT SOLUBLE VITAMINS | 46 | 2.20e-01 | 1.04e-01 | 0.94600 |
| REACTOME ATORVASTATIN ADME | 9 | 2.21e-01 | 2.36e-01 | 0.94600 |
| REACTOME TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS | 29 | 2.23e-01 | -1.31e-01 | 0.94600 |
| REACTOME REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM | 11 | 2.25e-01 | -2.11e-01 | 0.94600 |
| REACTOME CHAPERONE MEDIATED AUTOPHAGY | 20 | 2.25e-01 | 1.57e-01 | 0.94600 |
| REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | 73 | 2.25e-01 | -8.21e-02 | 0.94600 |
| REACTOME TIE2 SIGNALING | 18 | 2.25e-01 | -1.65e-01 | 0.94600 |
| REACTOME SIGNALING BY NOTCH2 | 32 | 2.26e-01 | 1.24e-01 | 0.94600 |
| REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ | 6 | 2.26e-01 | -2.85e-01 | 0.94600 |
| REACTOME INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING | 103 | 2.27e-01 | 6.90e-02 | 0.94600 |
| REACTOME SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER | 15 | 2.27e-01 | 1.80e-01 | 0.94600 |
| REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION | 62 | 2.28e-01 | -8.85e-02 | 0.94600 |
| REACTOME CGMP EFFECTS | 16 | 2.28e-01 | 1.74e-01 | 0.94600 |
| REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION | 59 | 2.29e-01 | 9.06e-02 | 0.94600 |
| REACTOME STIMULI SENSING CHANNELS | 100 | 2.31e-01 | 6.94e-02 | 0.94600 |
| REACTOME NUCLEOTIDE BIOSYNTHESIS | 14 | 2.31e-01 | -1.85e-01 | 0.94600 |
| REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | 11 | 2.32e-01 | -2.08e-01 | 0.94600 |
| REACTOME SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS | 74 | 2.34e-01 | -8.01e-02 | 0.94600 |
| REACTOME INTEGRATION OF PROVIRUS | 9 | 2.34e-01 | -2.29e-01 | 0.94600 |
| REACTOME MRNA SPLICING | 197 | 2.34e-01 | -4.91e-02 | 0.94600 |
| REACTOME RETINOID CYCLE DISEASE EVENTS | 11 | 2.35e-01 | 2.07e-01 | 0.94600 |
| REACTOME MATURATION OF SARS COV 2 NUCLEOPROTEIN | 15 | 2.35e-01 | -1.77e-01 | 0.94600 |
| REACTOME HDACS DEACETYLATE HISTONES | 85 | 2.35e-01 | 7.45e-02 | 0.94600 |
| REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | 54 | 2.35e-01 | -9.34e-02 | 0.94600 |
| REACTOME TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA | 17 | 2.35e-01 | 1.66e-01 | 0.94600 |
| REACTOME PHASE 1 INACTIVATION OF FAST NA CHANNELS | 6 | 2.35e-01 | 2.80e-01 | 0.94600 |
| REACTOME RORA ACTIVATES GENE EXPRESSION | 17 | 2.35e-01 | -1.66e-01 | 0.94600 |
| REACTOME GLUCONEOGENESIS | 33 | 2.35e-01 | -1.19e-01 | 0.94600 |
| REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | 15 | 2.36e-01 | 1.77e-01 | 0.94600 |
| REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | 19 | 2.37e-01 | -1.57e-01 | 0.94600 |
| REACTOME HYALURONAN METABOLISM | 17 | 2.37e-01 | 1.66e-01 | 0.94600 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS | 7 | 2.38e-01 | -2.58e-01 | 0.94600 |
| REACTOME DEADENYLATION OF MRNA | 25 | 2.38e-01 | 1.36e-01 | 0.94600 |
| REACTOME SYNAPTIC ADHESION LIKE MOLECULES | 19 | 2.39e-01 | -1.56e-01 | 0.94600 |
| REACTOME MEIOTIC RECOMBINATION | 80 | 2.42e-01 | 7.57e-02 | 0.94600 |
| REACTOME SARS COV 1 HOST INTERACTIONS | 92 | 2.43e-01 | -7.05e-02 | 0.94600 |
| REACTOME GLUCOSE METABOLISM | 90 | 2.45e-01 | -7.09e-02 | 0.94600 |
| REACTOME SLC TRANSPORTER DISORDERS | 94 | 2.46e-01 | 6.93e-02 | 0.94600 |
| REACTOME POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION | 27 | 2.47e-01 | -1.29e-01 | 0.94600 |
| REACTOME SUMOYLATION OF DNA REPLICATION PROTEINS | 46 | 2.47e-01 | -9.87e-02 | 0.94600 |
| REACTOME BASE EXCISION REPAIR AP SITE FORMATION | 59 | 2.48e-01 | 8.70e-02 | 0.94600 |
| REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES | 21 | 2.48e-01 | 1.46e-01 | 0.94600 |
| REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM | 78 | 2.48e-01 | -7.57e-02 | 0.94600 |
| REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS | 16 | 2.48e-01 | -1.67e-01 | 0.94600 |
| REACTOME NERVOUS SYSTEM DEVELOPMENT | 552 | 2.49e-01 | 2.87e-02 | 0.94600 |
| REACTOME TIGHT JUNCTION INTERACTIONS | 29 | 2.49e-01 | -1.24e-01 | 0.94600 |
| REACTOME VITAMIN D CALCIFEROL METABOLISM | 12 | 2.49e-01 | 1.92e-01 | 0.94600 |
| REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | 28 | 2.50e-01 | -1.26e-01 | 0.94600 |
| REACTOME INLA MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS | 9 | 2.50e-01 | -2.22e-01 | 0.94600 |
| REACTOME INTERLEUKIN 17 SIGNALING | 66 | 2.50e-01 | -8.19e-02 | 0.94600 |
| REACTOME SIGNALING BY NTRK2 TRKB | 25 | 2.50e-01 | 1.33e-01 | 0.94600 |
| REACTOME BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA | 5 | 2.50e-01 | 2.97e-01 | 0.94600 |
| REACTOME CHROMOSOME MAINTENANCE | 130 | 2.50e-01 | 5.84e-02 | 0.94600 |
| REACTOME SMALL INTERFERING RNA SIRNA BIOGENESIS | 9 | 2.51e-01 | -2.21e-01 | 0.94600 |
| REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | 10 | 2.52e-01 | 2.09e-01 | 0.94600 |
| REACTOME POLO LIKE KINASE MEDIATED EVENTS | 16 | 2.52e-01 | 1.66e-01 | 0.94600 |
| REACTOME HYALURONAN UPTAKE AND DEGRADATION | 12 | 2.52e-01 | 1.91e-01 | 0.94600 |
| REACTOME SYNTHESIS OF LIPOXINS LX | 6 | 2.53e-01 | 2.70e-01 | 0.94600 |
| REACTOME FERTILIZATION | 26 | 2.53e-01 | -1.29e-01 | 0.94600 |
| REACTOME RRNA PROCESSING | 192 | 2.54e-01 | 4.77e-02 | 0.94600 |
| REACTOME APOPTOTIC EXECUTION PHASE | 49 | 2.54e-01 | -9.41e-02 | 0.94600 |
| REACTOME ROBO RECEPTORS BIND AKAP5 | 9 | 2.54e-01 | -2.19e-01 | 0.94600 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE | 5 | 2.55e-01 | -2.94e-01 | 0.94600 |
| REACTOME REGULATED NECROSIS | 57 | 2.56e-01 | -8.70e-02 | 0.94600 |
| REACTOME G ALPHA Z SIGNALLING EVENTS | 48 | 2.56e-01 | 9.48e-02 | 0.94600 |
| REACTOME CHREBP ACTIVATES METABOLIC GENE EXPRESSION | 8 | 2.57e-01 | -2.32e-01 | 0.94600 |
| REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION | 12 | 2.57e-01 | 1.89e-01 | 0.94600 |
| REACTOME ONCOGENE INDUCED SENESCENCE | 35 | 2.58e-01 | -1.11e-01 | 0.94600 |
| REACTOME TNFR2 NON CANONICAL NF KB PATHWAY | 96 | 2.58e-01 | -6.68e-02 | 0.94600 |
| REACTOME G ALPHA Q SIGNALLING EVENTS | 206 | 2.58e-01 | 4.57e-02 | 0.94600 |
| REACTOME G1 S SPECIFIC TRANSCRIPTION | 28 | 2.58e-01 | 1.23e-01 | 0.94600 |
| REACTOME IRF3 MEDIATED INDUCTION OF TYPE I IFN | 13 | 2.59e-01 | -1.81e-01 | 0.94600 |
| REACTOME S PHASE | 159 | 2.59e-01 | -5.18e-02 | 0.94600 |
| REACTOME HDR THROUGH SINGLE STRAND ANNEALING SSA | 37 | 2.60e-01 | -1.07e-01 | 0.94600 |
| REACTOME RUNX3 REGULATES YAP1 MEDIATED TRANSCRIPTION | 8 | 2.61e-01 | 2.30e-01 | 0.94600 |
| REACTOME LYSINE CATABOLISM | 12 | 2.61e-01 | 1.87e-01 | 0.94600 |
| REACTOME SNRNP ASSEMBLY | 53 | 2.61e-01 | -8.92e-02 | 0.94600 |
| REACTOME SYNTHESIS OF DNA | 119 | 2.61e-01 | -5.96e-02 | 0.94600 |
| REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | 9 | 2.62e-01 | -2.16e-01 | 0.94600 |
| REACTOME NEGATIVE REGULATION OF MAPK PATHWAY | 41 | 2.62e-01 | -1.01e-01 | 0.94600 |
| REACTOME GRB7 EVENTS IN ERBB2 SIGNALING | 5 | 2.64e-01 | -2.89e-01 | 0.94600 |
| REACTOME PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING | 11 | 2.64e-01 | 1.95e-01 | 0.94600 |
| REACTOME STAT5 ACTIVATION | 7 | 2.64e-01 | -2.44e-01 | 0.94600 |
| REACTOME RET SIGNALING | 40 | 2.64e-01 | -1.02e-01 | 0.94600 |
| REACTOME SUPPRESSION OF APOPTOSIS | 7 | 2.65e-01 | -2.43e-01 | 0.94600 |
| REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS | 21 | 2.65e-01 | -1.41e-01 | 0.94600 |
| REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | 23 | 2.66e-01 | -1.34e-01 | 0.94600 |
| REACTOME SYNTHESIS OF 5 EICOSATETRAENOIC ACIDS | 9 | 2.66e-01 | 2.14e-01 | 0.94600 |
| REACTOME NUCLEAR ENVELOPE NE REASSEMBLY | 74 | 2.66e-01 | -7.48e-02 | 0.94600 |
| REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY | 94 | 2.67e-01 | 6.63e-02 | 0.94600 |
| REACTOME SUMO IS TRANSFERRED FROM E1 TO E2 UBE2I UBC9 | 7 | 2.67e-01 | -2.42e-01 | 0.94600 |
| REACTOME DEGRADATION OF GLI1 BY THE PROTEASOME | 59 | 2.67e-01 | -8.35e-02 | 0.94600 |
| REACTOME RHO GTPASES ACTIVATE PAKS | 19 | 2.69e-01 | 1.47e-01 | 0.94600 |
| REACTOME JOSEPHIN DOMAIN DUBS | 11 | 2.69e-01 | -1.93e-01 | 0.94600 |
| REACTOME GLYCOGEN METABOLISM | 22 | 2.69e-01 | -1.36e-01 | 0.94600 |
| REACTOME TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS | 26 | 2.70e-01 | -1.25e-01 | 0.94600 |
| REACTOME NS1 MEDIATED EFFECTS ON HOST PATHWAYS | 41 | 2.73e-01 | -9.90e-02 | 0.95400 |
| REACTOME UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN | 6 | 2.73e-01 | 2.58e-01 | 0.95400 |
| REACTOME SERINE BIOSYNTHESIS | 9 | 2.75e-01 | 2.10e-01 | 0.95800 |
| REACTOME UNFOLDED PROTEIN RESPONSE UPR | 88 | 2.76e-01 | -6.72e-02 | 0.95800 |
| REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | 16 | 2.76e-01 | 1.57e-01 | 0.95800 |
| REACTOME TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS | 55 | 2.77e-01 | -8.48e-02 | 0.95800 |
| REACTOME ION CHANNEL TRANSPORT | 172 | 2.77e-01 | 4.80e-02 | 0.95800 |
| REACTOME RAB REGULATION OF TRAFFICKING | 110 | 2.78e-01 | 5.98e-02 | 0.95900 |
| REACTOME INTEGRIN SIGNALING | 27 | 2.79e-01 | 1.20e-01 | 0.95900 |
| REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE | 9 | 2.81e-01 | -2.07e-01 | 0.96600 |
| REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | 122 | 2.83e-01 | -5.63e-02 | 0.97000 |
| REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | 29 | 2.85e-01 | -1.15e-01 | 0.97200 |
| REACTOME TRANSPORT AND SYNTHESIS OF PAPS | 6 | 2.85e-01 | 2.52e-01 | 0.97200 |
| REACTOME INTERLEUKIN 37 SIGNALING | 20 | 2.86e-01 | 1.38e-01 | 0.97200 |
| REACTOME NTRK2 ACTIVATES RAC1 | 5 | 2.86e-01 | 2.75e-01 | 0.97200 |
| REACTOME PI 3K CASCADE FGFR2 | 22 | 2.87e-01 | 1.31e-01 | 0.97200 |
| REACTOME INTERLEUKIN 6 FAMILY SIGNALING | 24 | 2.88e-01 | -1.25e-01 | 0.97200 |
| REACTOME RND1 GTPASE CYCLE | 41 | 2.88e-01 | -9.59e-02 | 0.97200 |
| REACTOME SEROTONIN RECEPTORS | 11 | 2.88e-01 | 1.85e-01 | 0.97200 |
| REACTOME PEPTIDE HORMONE BIOSYNTHESIS | 13 | 2.89e-01 | 1.70e-01 | 0.97200 |
| REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | 17 | 2.90e-01 | -1.48e-01 | 0.97400 |
| REACTOME GAP JUNCTION TRAFFICKING AND REGULATION | 49 | 2.91e-01 | 8.72e-02 | 0.97400 |
| REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS | 8 | 2.91e-01 | 2.15e-01 | 0.97400 |
| REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION | 9 | 2.92e-01 | 2.03e-01 | 0.97400 |
| REACTOME SIGNALING BY FGFR IN DISEASE | 62 | 2.92e-01 | -7.73e-02 | 0.97400 |
| REACTOME INTERLEUKIN 21 SIGNALING | 9 | 2.94e-01 | -2.02e-01 | 0.97400 |
| REACTOME KINESINS | 59 | 2.95e-01 | -7.88e-02 | 0.97400 |
| REACTOME HEDGEHOG ON STATE | 85 | 2.95e-01 | -6.57e-02 | 0.97400 |
| REACTOME HEME DEGRADATION | 15 | 2.95e-01 | 1.56e-01 | 0.97400 |
| REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B | 24 | 2.96e-01 | -1.23e-01 | 0.97400 |
| REACTOME RHOJ GTPASE CYCLE | 51 | 2.98e-01 | -8.42e-02 | 0.97400 |
| REACTOME SIGNALING BY ACTIVIN | 15 | 3.00e-01 | 1.55e-01 | 0.97400 |
| REACTOME CONDENSATION OF PROPHASE CHROMOSOMES | 66 | 3.00e-01 | 7.38e-02 | 0.97400 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3 | 11 | 3.00e-01 | 1.80e-01 | 0.97400 |
| REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | 26 | 3.02e-01 | 1.17e-01 | 0.97400 |
| REACTOME APEX1 INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | 7 | 3.02e-01 | 2.25e-01 | 0.97400 |
| REACTOME RAB GERANYLGERANYLATION | 57 | 3.05e-01 | -7.86e-02 | 0.97400 |
| REACTOME INTERLEUKIN 27 SIGNALING | 11 | 3.05e-01 | -1.79e-01 | 0.97400 |
| REACTOME REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS | 14 | 3.05e-01 | 1.58e-01 | 0.97400 |
| REACTOME PRE NOTCH PROCESSING IN GOLGI | 18 | 3.06e-01 | -1.39e-01 | 0.97400 |
| REACTOME DEFECTS IN VITAMIN AND COFACTOR METABOLISM | 21 | 3.07e-01 | -1.29e-01 | 0.97400 |
| REACTOME DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS | 15 | 3.08e-01 | -1.52e-01 | 0.97400 |
| REACTOME DEVELOPMENTAL BIOLOGY | 1115 | 3.08e-01 | 1.81e-02 | 0.97400 |
| REACTOME TRIGLYCERIDE METABOLISM | 35 | 3.09e-01 | 9.94e-02 | 0.97400 |
| REACTOME ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION | 16 | 3.09e-01 | 1.47e-01 | 0.97400 |
| REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES | 18 | 3.10e-01 | 1.38e-01 | 0.97400 |
| REACTOME FANCONI ANEMIA PATHWAY | 35 | 3.10e-01 | -9.92e-02 | 0.97400 |
| REACTOME EPH EPHRIN MEDIATED REPULSION OF CELLS | 50 | 3.11e-01 | 8.29e-02 | 0.97400 |
| REACTOME RHOV GTPASE CYCLE | 36 | 3.12e-01 | -9.74e-02 | 0.97400 |
| REACTOME HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS | 7 | 3.13e-01 | 2.20e-01 | 0.97400 |
| REACTOME DISEASES OF PROGRAMMED CELL DEATH | 96 | 3.14e-01 | 5.95e-02 | 0.97400 |
| REACTOME HORMONE LIGAND BINDING RECEPTORS | 12 | 3.15e-01 | -1.68e-01 | 0.97400 |
| REACTOME SIGNALING BY LRP5 MUTANTS | 6 | 3.15e-01 | 2.37e-01 | 0.97400 |
| REACTOME THE PHOTOTRANSDUCTION CASCADE | 32 | 3.17e-01 | 1.02e-01 | 0.97400 |
| REACTOME EPH EPHRIN SIGNALING | 90 | 3.17e-01 | 6.11e-02 | 0.97400 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING | 5 | 3.17e-01 | 2.58e-01 | 0.97400 |
| REACTOME INITIATION OF NUCLEAR ENVELOPE NE REFORMATION | 18 | 3.18e-01 | -1.36e-01 | 0.97400 |
| REACTOME GDP FUCOSE BIOSYNTHESIS | 6 | 3.18e-01 | -2.35e-01 | 0.97400 |
| REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION | 11 | 3.18e-01 | 1.74e-01 | 0.97400 |
| REACTOME MEIOSIS | 110 | 3.18e-01 | 5.51e-02 | 0.97400 |
| REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV 1 INFECTION | 5 | 3.18e-01 | -2.58e-01 | 0.97400 |
| REACTOME GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION | 42 | 3.18e-01 | -8.90e-02 | 0.97400 |
| REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | 20 | 3.19e-01 | -1.29e-01 | 0.97400 |
| REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS | 113 | 3.19e-01 | 5.42e-02 | 0.97400 |
| REACTOME TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION | 5 | 3.20e-01 | -2.57e-01 | 0.97400 |
| REACTOME METABOLISM OF RNA | 675 | 3.20e-01 | -2.24e-02 | 0.97400 |
| REACTOME PYROPTOSIS | 27 | 3.21e-01 | -1.10e-01 | 0.97400 |
| REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS | 5 | 3.22e-01 | -2.56e-01 | 0.97400 |
| REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | 123 | 3.22e-01 | -5.17e-02 | 0.97400 |
| REACTOME DISORDERS OF TRANSMEMBRANE TRANSPORTERS | 170 | 3.22e-01 | 4.40e-02 | 0.97400 |
| REACTOME HEMOSTASIS | 591 | 3.22e-01 | -2.38e-02 | 0.97400 |
| REACTOME SCAVENGING OF HEME FROM PLASMA | 13 | 3.23e-01 | -1.58e-01 | 0.97400 |
| REACTOME TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX | 14 | 3.24e-01 | -1.52e-01 | 0.97400 |
| REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS | 100 | 3.24e-01 | 5.71e-02 | 0.97400 |
| REACTOME APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS | 87 | 3.25e-01 | -6.10e-02 | 0.97400 |
| REACTOME VXPX CARGO TARGETING TO CILIUM | 20 | 3.25e-01 | 1.27e-01 | 0.97400 |
| REACTOME RHO GTPASE CYCLE | 423 | 3.26e-01 | -2.78e-02 | 0.97400 |
| REACTOME DEGRADATION OF DVL | 56 | 3.27e-01 | -7.58e-02 | 0.97400 |
| REACTOME O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS | 38 | 3.28e-01 | 9.17e-02 | 0.97400 |
| REACTOME DIGESTION | 17 | 3.28e-01 | -1.37e-01 | 0.97400 |
| REACTOME RUNX3 REGULATES BCL2L11 BIM TRANSCRIPTION | 5 | 3.30e-01 | 2.52e-01 | 0.97400 |
| REACTOME KERATINIZATION | 210 | 3.30e-01 | -3.90e-02 | 0.97400 |
| REACTOME SELENOAMINO ACID METABOLISM | 108 | 3.30e-01 | 5.42e-02 | 0.97400 |
| REACTOME LYSOSPHINGOLIPID AND LPA RECEPTORS | 14 | 3.30e-01 | 1.50e-01 | 0.97400 |
| REACTOME SIGNALING BY RECEPTOR TYROSINE KINASES | 507 | 3.31e-01 | 2.52e-02 | 0.97400 |
| REACTOME PEROXISOMAL PROTEIN IMPORT | 62 | 3.31e-01 | -7.13e-02 | 0.97400 |
| REACTOME CRMPS IN SEMA3A SIGNALING | 15 | 3.31e-01 | 1.45e-01 | 0.97400 |
| REACTOME GLYCOLYSIS | 70 | 3.31e-01 | -6.71e-02 | 0.97400 |
| REACTOME INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL | 14 | 3.32e-01 | -1.50e-01 | 0.97400 |
| REACTOME PROTEIN FOLDING | 96 | 3.33e-01 | 5.72e-02 | 0.97400 |
| REACTOME TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS | 82 | 3.34e-01 | 6.18e-02 | 0.97400 |
| REACTOME NUCLEOTIDE CATABOLISM | 35 | 3.34e-01 | -9.44e-02 | 0.97400 |
| REACTOME DAP12 INTERACTIONS | 37 | 3.34e-01 | -9.18e-02 | 0.97400 |
| REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2 | 17 | 3.34e-01 | 1.35e-01 | 0.97400 |
| REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS | 33 | 3.35e-01 | -9.70e-02 | 0.97400 |
| REACTOME REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS | 7 | 3.36e-01 | 2.10e-01 | 0.97400 |
| REACTOME INTERLEUKIN 1 PROCESSING | 9 | 3.36e-01 | -1.85e-01 | 0.97400 |
| REACTOME SCAVENGING BY CLASS A RECEPTORS | 19 | 3.37e-01 | -1.27e-01 | 0.97400 |
| REACTOME ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS | 24 | 3.37e-01 | 1.13e-01 | 0.97400 |
| REACTOME ELASTIC FIBRE FORMATION | 44 | 3.37e-01 | 8.36e-02 | 0.97400 |
| REACTOME TCR SIGNALING | 113 | 3.38e-01 | 5.21e-02 | 0.97400 |
| REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA | 28 | 3.39e-01 | -1.04e-01 | 0.97400 |
| REACTOME INTERFERON ALPHA BETA SIGNALING | 70 | 3.39e-01 | -6.61e-02 | 0.97400 |
| REACTOME PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE | 74 | 3.42e-01 | 6.39e-02 | 0.97400 |
| REACTOME PHASE 4 RESTING MEMBRANE POTENTIAL | 19 | 3.42e-01 | 1.26e-01 | 0.97400 |
| REACTOME PASSIVE TRANSPORT BY AQUAPORINS | 13 | 3.42e-01 | 1.52e-01 | 0.97400 |
| REACTOME TELOMERE C STRAND LAGGING STRAND SYNTHESIS | 33 | 3.43e-01 | -9.53e-02 | 0.97400 |
| REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4 | 33 | 3.44e-01 | 9.52e-02 | 0.97400 |
| REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES | 15 | 3.45e-01 | 1.41e-01 | 0.97400 |
| REACTOME DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS | 25 | 3.45e-01 | -1.09e-01 | 0.97400 |
| REACTOMEMATURATION OF SARS COV 1 NUCLEOPROTEIN | 11 | 3.45e-01 | -1.64e-01 | 0.97400 |
| REACTOME FGFR2 LIGAND BINDING AND ACTIVATION | 19 | 3.46e-01 | 1.25e-01 | 0.97400 |
| REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | 11 | 3.46e-01 | -1.64e-01 | 0.97400 |
| REACTOME REGULATION OF LIPID METABOLISM BY PPARALPHA | 115 | 3.46e-01 | -5.08e-02 | 0.97400 |
| REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | 15 | 3.47e-01 | -1.40e-01 | 0.97400 |
| REACTOME NETRIN MEDIATED REPULSION SIGNALS | 8 | 3.47e-01 | 1.92e-01 | 0.97400 |
| REACTOME VLDL CLEARANCE | 6 | 3.48e-01 | 2.21e-01 | 0.97400 |
| REACTOME COPI MEDIATED ANTEROGRADE TRANSPORT | 101 | 3.48e-01 | -5.41e-02 | 0.97400 |
| REACTOME EUKARYOTIC TRANSLATION ELONGATION | 87 | 3.48e-01 | 5.82e-02 | 0.97400 |
| REACTOME ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS | 41 | 3.50e-01 | 8.43e-02 | 0.97900 |
| REACTOME CELL CELL JUNCTION ORGANIZATION | 64 | 3.52e-01 | -6.73e-02 | 0.97900 |
| REACTOME SARS COV 2 INFECTION | 281 | 3.52e-01 | -3.22e-02 | 0.97900 |
| REACTOME TRANSLESION SYNTHESIS BY POLK | 17 | 3.53e-01 | -1.30e-01 | 0.97900 |
| REACTOME RND2 GTPASE CYCLE | 42 | 3.54e-01 | -8.26e-02 | 0.97900 |
| REACTOME DISEASES OF DNA REPAIR | 51 | 3.55e-01 | -7.49e-02 | 0.97900 |
| REACTOME FORMATION OF XYLULOSE 5 PHOSPHATE | 5 | 3.56e-01 | -2.38e-01 | 0.97900 |
| REACTOME G2 M DNA REPLICATION CHECKPOINT | 5 | 3.56e-01 | 2.38e-01 | 0.97900 |
| REACTOME FLT3 SIGNALING BY CBL MUTANTS | 7 | 3.57e-01 | -2.01e-01 | 0.97900 |
| REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX | 57 | 3.57e-01 | 7.06e-02 | 0.97900 |
| REACTOME SPERM MOTILITY AND TAXES | 9 | 3.58e-01 | -1.77e-01 | 0.97900 |
| REACTOME ASPIRIN ADME | 42 | 3.59e-01 | 8.17e-02 | 0.97900 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING | 5 | 3.60e-01 | 2.36e-01 | 0.97900 |
| REACTOME DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX | 83 | 3.62e-01 | -5.79e-02 | 0.97900 |
| REACTOME FORMATION OF LATERAL PLATE MESODERM | 5 | 3.62e-01 | 2.35e-01 | 0.97900 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS | 9 | 3.63e-01 | -1.75e-01 | 0.97900 |
| REACTOME CONDENSATION OF PROMETAPHASE CHROMOSOMES | 11 | 3.63e-01 | 1.58e-01 | 0.97900 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING | 6 | 3.64e-01 | 2.14e-01 | 0.97900 |
| REACTOME CELLULAR HEXOSE TRANSPORT | 21 | 3.65e-01 | -1.14e-01 | 0.97900 |
| REACTOME DNA DOUBLE STRAND BREAK REPAIR | 162 | 3.65e-01 | -4.12e-02 | 0.97900 |
| REACTOME INWARDLY RECTIFYING K CHANNELS | 35 | 3.66e-01 | 8.84e-02 | 0.97900 |
| REACTOME RHOD GTPASE CYCLE | 49 | 3.66e-01 | -7.47e-02 | 0.97900 |
| REACTOME BH3 ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI APOPTOTIC BCL 2 MEMBERS | 9 | 3.66e-01 | -1.74e-01 | 0.97900 |
| REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS | 15 | 3.66e-01 | 1.35e-01 | 0.97900 |
| REACTOME CELLULAR SENESCENCE | 189 | 3.67e-01 | -3.81e-02 | 0.97900 |
| REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION | 250 | 3.67e-01 | 3.32e-02 | 0.97900 |
| REACTOME P75NTR REGULATES AXONOGENESIS | 9 | 3.67e-01 | 1.74e-01 | 0.97900 |
| REACTOME MINERALOCORTICOID BIOSYNTHESIS | 6 | 3.67e-01 | -2.13e-01 | 0.97900 |
| REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | 23 | 3.67e-01 | -1.09e-01 | 0.97900 |
| REACTOME PROPIONYL COA CATABOLISM | 5 | 3.69e-01 | -2.32e-01 | 0.98100 |
| REACTOME COENZYME A BIOSYNTHESIS | 8 | 3.70e-01 | 1.83e-01 | 0.98200 |
| REACTOME G ALPHA S SIGNALLING EVENTS | 155 | 3.71e-01 | 4.17e-02 | 0.98300 |
| REACTOME SIGNALING BY VEGF | 102 | 3.72e-01 | -5.11e-02 | 0.98400 |
| REACTOME MULTIFUNCTIONAL ANION EXCHANGERS | 9 | 3.73e-01 | 1.71e-01 | 0.98400 |
| REACTOME TELOMERE MAINTENANCE | 106 | 3.74e-01 | 5.00e-02 | 0.98400 |
| REACTOME MTORC1 MEDIATED SIGNALLING | 23 | 3.76e-01 | -1.07e-01 | 0.98400 |
| REACTOME ESR MEDIATED SIGNALING | 210 | 3.76e-01 | 3.54e-02 | 0.98400 |
| REACTOME SEMAPHORIN INTERACTIONS | 61 | 3.77e-01 | 6.54e-02 | 0.98400 |
| REACTOME EXTRA NUCLEAR ESTROGEN SIGNALING | 74 | 3.77e-01 | 5.94e-02 | 0.98400 |
| REACTOME CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND | 9 | 3.78e-01 | 1.70e-01 | 0.98400 |
| REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | 9 | 3.78e-01 | 1.70e-01 | 0.98400 |
| REACTOME PECAM1 INTERACTIONS | 12 | 3.78e-01 | 1.47e-01 | 0.98400 |
| REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION | 10 | 3.80e-01 | 1.60e-01 | 0.98400 |
| REACTOME OAS ANTIVIRAL RESPONSE | 8 | 3.80e-01 | -1.79e-01 | 0.98400 |
| REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS | 29 | 3.80e-01 | 9.41e-02 | 0.98400 |
| REACTOME DEFECTIVE EXT2 CAUSES EXOSTOSES 2 | 12 | 3.81e-01 | -1.46e-01 | 0.98400 |
| REACTOME RAF INDEPENDENT MAPK1 3 ACTIVATION | 22 | 3.81e-01 | -1.08e-01 | 0.98400 |
| REACTOME RNA POLYMERASE II PRE TRANSCRIPTION EVENTS | 77 | 3.81e-01 | 5.77e-02 | 0.98400 |
| REACTOME NUCLEAR IMPORT OF REV PROTEIN | 34 | 3.81e-01 | -8.67e-02 | 0.98400 |
| REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE | 35 | 3.82e-01 | -8.55e-02 | 0.98400 |
| REACTOME MITOCHONDRIAL PROTEIN IMPORT | 58 | 3.83e-01 | -6.63e-02 | 0.98500 |
| REACTOME CARGO CONCENTRATION IN THE ER | 32 | 3.83e-01 | -8.91e-02 | 0.98500 |
| REACTOME CATION COUPLED CHLORIDE COTRANSPORTERS | 7 | 3.87e-01 | -1.89e-01 | 0.98600 |
| REACTOME REGULATION OF NPAS4 GENE TRANSCRIPTION | 5 | 3.87e-01 | 2.23e-01 | 0.98600 |
| REACTOME UPTAKE AND ACTIONS OF BACTERIAL TOXINS | 28 | 3.87e-01 | 9.45e-02 | 0.98600 |
| REACTOME DISEASES OF BASE EXCISION REPAIR | 5 | 3.88e-01 | 2.23e-01 | 0.98600 |
| REACTOME NADE MODULATES DEATH SIGNALLING | 5 | 3.88e-01 | 2.23e-01 | 0.98600 |
| REACTOME SIGNALING BY LEPTIN | 11 | 3.88e-01 | -1.50e-01 | 0.98600 |
| REACTOME DSCAM INTERACTIONS | 11 | 3.88e-01 | -1.50e-01 | 0.98600 |
| REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN | 37 | 3.89e-01 | -8.19e-02 | 0.98600 |
| REACTOME CTLA4 INHIBITORY SIGNALING | 21 | 3.90e-01 | 1.08e-01 | 0.98600 |
| REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | 27 | 3.90e-01 | 9.55e-02 | 0.98600 |
| REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION | 32 | 3.90e-01 | -8.78e-02 | 0.98600 |
| REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | 11 | 3.91e-01 | -1.49e-01 | 0.98600 |
| REACTOME MET PROMOTES CELL MOTILITY | 41 | 3.93e-01 | -7.71e-02 | 0.99000 |
| REACTOME MAPK1 ERK2 ACTIVATION | 9 | 3.95e-01 | -1.64e-01 | 0.99200 |
| REACTOME SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL | 25 | 3.95e-01 | 9.82e-02 | 0.99200 |
| REACTOME IRAK1 RECRUITS IKK COMPLEX | 12 | 3.97e-01 | -1.41e-01 | 0.99200 |
| REACTOME COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES | 65 | 3.98e-01 | 6.06e-02 | 0.99200 |
| REACTOME TRANSCRIPTIONAL REGULATION BY E2F6 | 32 | 3.98e-01 | -8.63e-02 | 0.99200 |
| REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | 19 | 3.99e-01 | -1.12e-01 | 0.99200 |
| REACTOME RHOBTB2 GTPASE CYCLE | 22 | 4.00e-01 | -1.04e-01 | 0.99200 |
| REACTOME RHO GTPASES ACTIVATE PKNS | 86 | 4.00e-01 | 5.25e-02 | 0.99200 |
| REACTOME MITOCHONDRIAL TRANSLATION | 93 | 4.01e-01 | -5.04e-02 | 0.99200 |
| REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE | 69 | 4.02e-01 | 5.84e-02 | 0.99200 |
| REACTOME ABACAVIR TRANSMEMBRANE TRANSPORT | 5 | 4.03e-01 | 2.16e-01 | 0.99200 |
| REACTOME EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION | 27 | 4.03e-01 | -9.29e-02 | 0.99200 |
| REACTOME NUCLEAR EVENTS MEDIATED BY NFE2L2 | 77 | 4.05e-01 | -5.49e-02 | 0.99200 |
| REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A | 26 | 4.05e-01 | -9.43e-02 | 0.99200 |
| REACTOME GROWTH HORMONE RECEPTOR SIGNALING | 24 | 4.05e-01 | -9.81e-02 | 0.99200 |
| REACTOME HS GAG DEGRADATION | 19 | 4.07e-01 | -1.10e-01 | 0.99200 |
| REACTOME NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY | 6 | 4.09e-01 | 1.95e-01 | 0.99200 |
| REACTOME INOSITOL PHOSPHATE METABOLISM | 45 | 4.10e-01 | 7.10e-02 | 0.99200 |
| REACTOME RA BIOSYNTHESIS PATHWAY | 22 | 4.11e-01 | 1.01e-01 | 0.99200 |
| REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | 81 | 4.12e-01 | 5.28e-02 | 0.99200 |
| REACTOME CROSSLINKING OF COLLAGEN FIBRILS | 16 | 4.12e-01 | 1.19e-01 | 0.99200 |
| REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR2 | 29 | 4.12e-01 | 8.81e-02 | 0.99200 |
| REACTOME ACYL CHAIN REMODELING OF DAG AND TAG | 5 | 4.12e-01 | 2.12e-01 | 0.99200 |
| REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | 31 | 4.13e-01 | -8.50e-02 | 0.99200 |
| REACTOME REGULATION OF BACH1 ACTIVITY | 11 | 4.13e-01 | -1.42e-01 | 0.99200 |
| REACTOME MYOCLONIC EPILEPSY OF LAFORA | 9 | 4.15e-01 | -1.57e-01 | 0.99200 |
| REACTOME PLATELET HOMEOSTASIS | 85 | 4.15e-01 | 5.11e-02 | 0.99200 |
| REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE | 71 | 4.15e-01 | 5.59e-02 | 0.99200 |
| REACTOME MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION | 15 | 4.16e-01 | -1.21e-01 | 0.99200 |
| REACTOME FGFR2B LIGAND BINDING AND ACTIVATION | 10 | 4.16e-01 | 1.48e-01 | 0.99200 |
| REACTOME REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE | 81 | 4.16e-01 | -5.22e-02 | 0.99200 |
| REACTOME TRNA PROCESSING IN THE NUCLEUS | 58 | 4.17e-01 | 6.17e-02 | 0.99200 |
| REACTOME VASOPRESSIN LIKE RECEPTORS | 5 | 4.17e-01 | -2.10e-01 | 0.99200 |
| REACTOME NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 22 | 4.17e-01 | 1.00e-01 | 0.99200 |
| REACTOME RUNX3 REGULATES P14 ARF | 10 | 4.17e-01 | -1.48e-01 | 0.99200 |
| REACTOME CROSS PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS PHAGOSOMES | 6 | 4.18e-01 | 1.91e-01 | 0.99200 |
| REACTOME FORMATION OF TC NER PRE INCISION COMPLEX | 51 | 4.22e-01 | -6.50e-02 | 0.99200 |
| REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES | 12 | 4.23e-01 | 1.34e-01 | 0.99200 |
| REACTOME INSULIN RECEPTOR SIGNALLING CASCADE | 53 | 4.23e-01 | 6.36e-02 | 0.99200 |
| REACTOME SIGNALLING TO RAS | 20 | 4.23e-01 | -1.03e-01 | 0.99200 |
| REACTOME G1 S DNA DAMAGE CHECKPOINTS | 67 | 4.25e-01 | -5.63e-02 | 0.99200 |
| REACTOME CELL CELL COMMUNICATION | 126 | 4.27e-01 | -4.10e-02 | 0.99200 |
| REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY | 33 | 4.27e-01 | 7.98e-02 | 0.99200 |
| REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD4 | 15 | 4.27e-01 | 1.18e-01 | 0.99200 |
| REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS | 35 | 4.28e-01 | -7.74e-02 | 0.99200 |
| REACTOME ANTIGEN PROCESSING CROSS PRESENTATION | 98 | 4.29e-01 | -4.62e-02 | 0.99200 |
| REACTOME ERYTHROPOIETIN ACTIVATES RAS | 14 | 4.30e-01 | -1.22e-01 | 0.99200 |
| REACTOME SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE | 91 | 4.30e-01 | -4.79e-02 | 0.99200 |
| REACTOME SUMOYLATION OF RNA BINDING PROTEINS | 47 | 4.30e-01 | -6.65e-02 | 0.99200 |
| REACTOME RHOF GTPASE CYCLE | 40 | 4.31e-01 | -7.20e-02 | 0.99200 |
| REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | 17 | 4.32e-01 | 1.10e-01 | 0.99200 |
| REACTOME ION TRANSPORT BY P TYPE ATPASES | 51 | 4.34e-01 | 6.33e-02 | 0.99200 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FYN | 7 | 4.35e-01 | 1.71e-01 | 0.99200 |
| REACTOME HCMV LATE EVENTS | 110 | 4.35e-01 | 4.31e-02 | 0.99200 |
| REACTOME INTERFERON SIGNALING | 193 | 4.35e-01 | -3.26e-02 | 0.99200 |
| REACTOME IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN | 5 | 4.36e-01 | 2.01e-01 | 0.99200 |
| REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS | 16 | 4.36e-01 | 1.13e-01 | 0.99200 |
| REACTOME DNA REPLICATION INITIATION | 7 | 4.36e-01 | -1.70e-01 | 0.99200 |
| REACTOME EUKARYOTIC TRANSLATION INITIATION | 110 | 4.37e-01 | 4.29e-02 | 0.99200 |
| REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION | 23 | 4.37e-01 | 9.37e-02 | 0.99200 |
| REACTOME TERMINAL PATHWAY OF COMPLEMENT | 8 | 4.37e-01 | -1.59e-01 | 0.99200 |
| REACTOME HCMV INFECTION | 152 | 4.37e-01 | 3.65e-02 | 0.99200 |
| REACTOME SCAVENGING BY CLASS B RECEPTORS | 6 | 4.38e-01 | 1.83e-01 | 0.99200 |
| REACTOME FCGR ACTIVATION | 11 | 4.39e-01 | 1.35e-01 | 0.99200 |
| REACTOME RUNX3 REGULATES NOTCH SIGNALING | 13 | 4.40e-01 | 1.24e-01 | 0.99200 |
| REACTOME REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA | 15 | 4.40e-01 | -1.15e-01 | 0.99200 |
| REACTOME PREDNISONE ADME | 10 | 4.41e-01 | 1.41e-01 | 0.99200 |
| REACTOME KILLING MECHANISMS | 11 | 4.41e-01 | -1.34e-01 | 0.99200 |
| REACTOME GAP JUNCTION DEGRADATION | 12 | 4.42e-01 | 1.28e-01 | 0.99200 |
| REACTOME SUMOYLATION OF SUMOYLATION PROTEINS | 35 | 4.44e-01 | -7.48e-02 | 0.99200 |
| REACTOME EGFR TRANSACTIVATION BY GASTRIN | 9 | 4.44e-01 | 1.47e-01 | 0.99200 |
| REACTOME GLUTAMATE AND GLUTAMINE METABOLISM | 13 | 4.44e-01 | -1.23e-01 | 0.99200 |
| REACTOME BIOTIN TRANSPORT AND METABOLISM | 10 | 4.46e-01 | -1.39e-01 | 0.99200 |
| REACTOME SIGNALLING TO ERKS | 34 | 4.46e-01 | -7.56e-02 | 0.99200 |
| REACTOME CD28 DEPENDENT PI3K AKT SIGNALING | 22 | 4.46e-01 | 9.39e-02 | 0.99200 |
| REACTOME SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS | 14 | 4.46e-01 | -1.18e-01 | 0.99200 |
| REACTOME TYROSINE CATABOLISM | 5 | 4.47e-01 | -1.97e-01 | 0.99200 |
| REACTOME TRNA AMINOACYLATION | 40 | 4.47e-01 | -6.95e-02 | 0.99200 |
| REACTOME REPRESSION OF WNT TARGET GENES | 14 | 4.48e-01 | 1.17e-01 | 0.99200 |
| REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS | 55 | 4.48e-01 | 5.92e-02 | 0.99200 |
| REACTOME TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY | 16 | 4.49e-01 | -1.09e-01 | 0.99200 |
| REACTOME GAP JUNCTION ASSEMBLY | 36 | 4.49e-01 | 7.29e-02 | 0.99200 |
| REACTOME ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA | 5 | 4.49e-01 | -1.95e-01 | 0.99200 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN | 13 | 4.51e-01 | -1.21e-01 | 0.99200 |
| REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS | 13 | 4.52e-01 | 1.21e-01 | 0.99200 |
| REACTOME NEGATIVE REGULATION OF NOTCH4 SIGNALING | 53 | 4.52e-01 | -5.97e-02 | 0.99200 |
| REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | 38 | 4.52e-01 | 7.05e-02 | 0.99200 |
| REACTOME SIGNALING BY ERYTHROPOIETIN | 25 | 4.54e-01 | -8.65e-02 | 0.99200 |
| REACTOME NRAGE SIGNALS DEATH THROUGH JNK | 53 | 4.54e-01 | 5.94e-02 | 0.99200 |
| REACTOME ASSEMBLY OF THE HIV VIRION | 16 | 4.55e-01 | -1.08e-01 | 0.99200 |
| REACTOME SIGNALING BY FGFR2 IN DISEASE | 42 | 4.56e-01 | 6.64e-02 | 0.99200 |
| REACTOME RND3 GTPASE CYCLE | 41 | 4.57e-01 | -6.71e-02 | 0.99200 |
| REACTOME RECYCLING PATHWAY OF L1 | 43 | 4.58e-01 | 6.54e-02 | 0.99200 |
| REACTOME TP53 REGULATES METABOLIC GENES | 81 | 4.59e-01 | -4.76e-02 | 0.99200 |
| REACTOME NEGATIVE REGULATION OF ACTIVITY OF TFAP2 AP 2 FAMILY TRANSCRIPTION FACTORS | 10 | 4.59e-01 | 1.35e-01 | 0.99200 |
| REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION | 32 | 4.61e-01 | 7.53e-02 | 0.99200 |
| REACTOME NETRIN 1 SIGNALING | 49 | 4.63e-01 | 6.07e-02 | 0.99200 |
| REACTOME EXTENSION OF TELOMERES | 49 | 4.63e-01 | -6.06e-02 | 0.99200 |
| REACTOME DEFECTS IN COBALAMIN B12 METABOLISM | 13 | 4.63e-01 | -1.18e-01 | 0.99200 |
| REACTOME LINOLEIC ACID LA METABOLISM | 7 | 4.63e-01 | -1.60e-01 | 0.99200 |
| REACTOME BETA OXIDATION OF PRISTANOYL COA | 9 | 4.63e-01 | -1.41e-01 | 0.99200 |
| REACTOME UCH PROTEINASES | 99 | 4.65e-01 | -4.25e-02 | 0.99200 |
| REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | 46 | 4.66e-01 | -6.21e-02 | 0.99200 |
| REACTOME CD28 CO STIMULATION | 32 | 4.66e-01 | 7.44e-02 | 0.99200 |
| REACTOME RELAXIN RECEPTORS | 8 | 4.66e-01 | 1.49e-01 | 0.99200 |
| REACTOME ENOS ACTIVATION | 11 | 4.66e-01 | 1.27e-01 | 0.99200 |
| REACTOME PTK6 REGULATES CELL CYCLE | 6 | 4.67e-01 | -1.72e-01 | 0.99200 |
| REACTOME PREVENTION OF PHAGOSOMAL LYSOSOMAL FUSION | 9 | 4.68e-01 | -1.40e-01 | 0.99200 |
| REACTOME RHOA GTPASE CYCLE | 142 | 4.70e-01 | -3.52e-02 | 0.99200 |
| REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | 63 | 4.70e-01 | -5.26e-02 | 0.99200 |
| REACTOME SIGNALING BY MAPK MUTANTS | 6 | 4.70e-01 | -1.70e-01 | 0.99200 |
| REACTOME COMPLEX I BIOGENESIS | 49 | 4.71e-01 | 5.96e-02 | 0.99200 |
| REACTOME MAPK FAMILY SIGNALING CASCADES | 314 | 4.72e-01 | -2.36e-02 | 0.99200 |
| REACTOME DEFECTS IN BIOTIN BTN METABOLISM | 8 | 4.73e-01 | -1.47e-01 | 0.99200 |
| REACTOME SYNTHESIS OF 15 EICOSATETRAENOIC ACID DERIVATIVES | 6 | 4.73e-01 | -1.69e-01 | 0.99200 |
| REACTOME ETHANOL OXIDATION | 12 | 4.75e-01 | -1.19e-01 | 0.99200 |
| REACTOME RECYCLING OF BILE ACIDS AND SALTS | 18 | 4.75e-01 | -9.72e-02 | 0.99200 |
| REACTOME DEADENYLATION DEPENDENT MRNA DECAY | 56 | 4.76e-01 | 5.50e-02 | 0.99200 |
| REACTOME MATURATION OF PROTEIN 3A | 9 | 4.77e-01 | -1.37e-01 | 0.99200 |
| REACTOME KERATAN SULFATE BIOSYNTHESIS | 28 | 4.80e-01 | -7.72e-02 | 0.99200 |
| REACTOME REGULATED PROTEOLYSIS OF P75NTR | 11 | 4.81e-01 | 1.23e-01 | 0.99200 |
| REACTOME LATE SARS COV 2 INFECTION EVENTS | 67 | 4.81e-01 | -4.98e-02 | 0.99200 |
| REACTOME BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA | 5 | 4.82e-01 | 1.82e-01 | 0.99200 |
| REACTOME MHC CLASS II ANTIGEN PRESENTATION | 121 | 4.83e-01 | -3.69e-02 | 0.99200 |
| REACTOME NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10 | 12 | 4.83e-01 | -1.17e-01 | 0.99200 |
| REACTOME INTERLEUKIN 1 SIGNALING | 110 | 4.84e-01 | -3.86e-02 | 0.99200 |
| REACTOME IKBA VARIANT LEADS TO EDA ID | 6 | 4.85e-01 | -1.65e-01 | 0.99200 |
| REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | 15 | 4.86e-01 | 1.04e-01 | 0.99200 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES | 49 | 4.88e-01 | 5.73e-02 | 0.99200 |
| REACTOME RHOBTB1 GTPASE CYCLE | 22 | 4.88e-01 | -8.54e-02 | 0.99200 |
| REACTOME SYNTHESIS OF DIPHTHAMIDE EEF2 | 8 | 4.89e-01 | 1.41e-01 | 0.99200 |
| REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1 | 20 | 4.91e-01 | 8.90e-02 | 0.99200 |
| REACTOME UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION | 19 | 4.91e-01 | 9.13e-02 | 0.99200 |
| REACTOME ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN | 13 | 4.91e-01 | 1.10e-01 | 0.99200 |
| REACTOME TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS | 43 | 4.93e-01 | -6.04e-02 | 0.99200 |
| REACTOME REGULATION OF PTEN GENE TRANSCRIPTION | 59 | 4.93e-01 | -5.16e-02 | 0.99200 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH CDK5 | 6 | 4.93e-01 | 1.62e-01 | 0.99200 |
| REACTOME P2Y RECEPTORS | 9 | 4.93e-01 | 1.32e-01 | 0.99200 |
| REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX | 15 | 4.94e-01 | -1.02e-01 | 0.99200 |
| REACTOME INTERLEUKIN 12 SIGNALING | 43 | 4.94e-01 | -6.03e-02 | 0.99200 |
| REACTOME CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY | 12 | 4.94e-01 | 1.14e-01 | 0.99200 |
| REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX | 13 | 4.95e-01 | -1.09e-01 | 0.99200 |
| REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | 91 | 4.95e-01 | -4.14e-02 | 0.99200 |
| REACTOME DEFECTIVE CHSY1 CAUSES TPBS | 7 | 4.96e-01 | 1.49e-01 | 0.99200 |
| REACTOME SIGNALING BY NOTCH | 234 | 4.96e-01 | 2.58e-02 | 0.99200 |
| REACTOME METABOLISM OF NUCLEOTIDES | 94 | 4.97e-01 | -4.06e-02 | 0.99200 |
| REACTOME DISEASES OF GLYCOSYLATION | 137 | 4.97e-01 | -3.36e-02 | 0.99200 |
| REACTOME TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS | 36 | 4.97e-01 | 6.54e-02 | 0.99200 |
| REACTOME RHO GTPASES ACTIVATE IQGAPS | 31 | 4.98e-01 | 7.03e-02 | 0.99200 |
| REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2 | 13 | 4.99e-01 | 1.08e-01 | 0.99200 |
| REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | 35 | 4.99e-01 | -6.60e-02 | 0.99200 |
| REACTOME SCAVENGING BY CLASS F RECEPTORS | 6 | 5.00e-01 | -1.59e-01 | 0.99200 |
| REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | 14 | 5.00e-01 | -1.04e-01 | 0.99200 |
| REACTOME RUNX3 REGULATES CDKN1A TRANSCRIPTION | 7 | 5.00e-01 | 1.47e-01 | 0.99200 |
| REACTOME GAB1 SIGNALOSOME | 17 | 5.03e-01 | 9.39e-02 | 0.99200 |
| REACTOME DEFECTIVE CHST14 CAUSES EDS MUSCULOCONTRACTURAL TYPE | 7 | 5.04e-01 | 1.46e-01 | 0.99200 |
| REACTOME RESPONSE TO METAL IONS | 14 | 5.05e-01 | -1.03e-01 | 0.99200 |
| REACTOME METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION | 15 | 5.05e-01 | 9.93e-02 | 0.99200 |
| REACTOME HOMOLOGY DIRECTED REPAIR | 132 | 5.06e-01 | -3.35e-02 | 0.99200 |
| REACTOME SIGNALING BY CSF1 M CSF IN MYELOID CELLS | 30 | 5.06e-01 | 7.01e-02 | 0.99200 |
| REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION | 100 | 5.07e-01 | 3.84e-02 | 0.99200 |
| REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL | 41 | 5.07e-01 | -5.99e-02 | 0.99200 |
| REACTOME INDUCTION OF CELL CELL FUSION | 12 | 5.08e-01 | 1.10e-01 | 0.99200 |
| REACTOME STABILIZATION OF P53 | 56 | 5.08e-01 | -5.11e-02 | 0.99200 |
| REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS | 42 | 5.09e-01 | -5.89e-02 | 0.99200 |
| REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND | 14 | 5.10e-01 | -1.02e-01 | 0.99200 |
| REACTOME PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING | 5 | 5.10e-01 | -1.70e-01 | 0.99200 |
| REACTOME SODIUM COUPLED PHOSPHATE COTRANSPORTERS | 5 | 5.12e-01 | 1.69e-01 | 0.99200 |
| REACTOME ERKS ARE INACTIVATED | 13 | 5.12e-01 | 1.05e-01 | 0.99200 |
| REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX | 91 | 5.12e-01 | -3.97e-02 | 0.99200 |
| REACTOME PLASMA LIPOPROTEIN REMODELING | 33 | 5.13e-01 | 6.59e-02 | 0.99200 |
| REACTOME TACHYKININ RECEPTORS BIND TACHYKININS | 5 | 5.13e-01 | -1.69e-01 | 0.99200 |
| REACTOME NFE2L2 REGULATING ANTI OXIDANT DETOXIFICATION ENZYMES | 17 | 5.13e-01 | -9.16e-02 | 0.99200 |
| REACTOME MITOTIC TELOPHASE CYTOKINESIS | 11 | 5.14e-01 | -1.14e-01 | 0.99200 |
| REACTOME PERK REGULATES GENE EXPRESSION | 31 | 5.14e-01 | 6.77e-02 | 0.99200 |
| REACTOME SIGNALING BY KIT IN DISEASE | 20 | 5.16e-01 | -8.38e-02 | 0.99200 |
| REACTOME SIGNALING BY PDGFR IN DISEASE | 20 | 5.17e-01 | -8.37e-02 | 0.99200 |
| REACTOME REGULATION OF TP53 ACTIVITY THROUGH METHYLATION | 19 | 5.19e-01 | -8.55e-02 | 0.99200 |
| REACTOME REGULATION OF NF KAPPA B SIGNALING | 17 | 5.19e-01 | 9.04e-02 | 0.99200 |
| REACTOME MET INTERACTS WITH TNS PROTEINS | 5 | 5.20e-01 | -1.66e-01 | 0.99200 |
| REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | 51 | 5.20e-01 | -5.21e-02 | 0.99200 |
| REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | 14 | 5.20e-01 | 9.93e-02 | 0.99200 |
| REACTOME COLLAGEN DEGRADATION | 61 | 5.21e-01 | 4.75e-02 | 0.99200 |
| REACTOME ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS | 27 | 5.22e-01 | 7.12e-02 | 0.99200 |
| REACTOME PTK6 PROMOTES HIF1A STABILIZATION | 6 | 5.22e-01 | 1.51e-01 | 0.99200 |
| REACTOME NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 11 | 5.22e-01 | 1.11e-01 | 0.99200 |
| REACTOME PKMTS METHYLATE HISTONE LYSINES | 64 | 5.22e-01 | 4.62e-02 | 0.99200 |
| REACTOME 2 LTR CIRCLE FORMATION | 7 | 5.23e-01 | -1.39e-01 | 0.99200 |
| REACTOME POST TRANSCRIPTIONAL SILENCING BY SMALL RNAS | 7 | 5.24e-01 | -1.39e-01 | 0.99200 |
| REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | 23 | 5.26e-01 | 7.64e-02 | 0.99200 |
| REACTOME LEISHMANIA INFECTION | 156 | 5.27e-01 | -2.94e-02 | 0.99200 |
| REACTOME ACTIVATION OF PPARGC1A PGC 1ALPHA BY PHOSPHORYLATION | 10 | 5.27e-01 | 1.15e-01 | 0.99200 |
| REACTOME GLUCAGON TYPE LIGAND RECEPTORS | 32 | 5.28e-01 | -6.45e-02 | 0.99200 |
| REACTOME DIGESTION OF DIETARY LIPID | 7 | 5.28e-01 | -1.38e-01 | 0.99200 |
| REACTOME LAGGING STRAND SYNTHESIS | 19 | 5.30e-01 | -8.33e-02 | 0.99200 |
| REACTOME RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS | 9 | 5.30e-01 | -1.21e-01 | 0.99200 |
| REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX | 9 | 5.30e-01 | -1.21e-01 | 0.99200 |
| REACTOME SMOOTH MUSCLE CONTRACTION | 43 | 5.30e-01 | 5.53e-02 | 0.99200 |
| REACTOME EARLY SARS COV 2 INFECTION EVENTS | 34 | 5.31e-01 | -6.22e-02 | 0.99200 |
| REACTOME RAF ACTIVATION | 33 | 5.31e-01 | -6.30e-02 | 0.99200 |
| REACTOME ORGANIC CATION TRANSPORT | 10 | 5.32e-01 | -1.14e-01 | 0.99200 |
| REACTOME NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 25 | 5.33e-01 | 7.21e-02 | 0.99200 |
| REACTOME DAP12 SIGNALING | 27 | 5.33e-01 | -6.93e-02 | 0.99200 |
| REACTOME RIPK1 MEDIATED REGULATED NECROSIS | 30 | 5.33e-01 | -6.57e-02 | 0.99200 |
| REACTOME TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA | 36 | 5.33e-01 | -6.00e-02 | 0.99200 |
| REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | 21 | 5.35e-01 | -7.82e-02 | 0.99200 |
| REACTOME ARYL HYDROCARBON RECEPTOR SIGNALLING | 6 | 5.36e-01 | 1.46e-01 | 0.99200 |
| REACTOME RHOH GTPASE CYCLE | 37 | 5.37e-01 | -5.87e-02 | 0.99200 |
| REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION | 26 | 5.37e-01 | -6.99e-02 | 0.99200 |
| REACTOME HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE | 43 | 5.38e-01 | -5.43e-02 | 0.99200 |
| REACTOME SUMOYLATION OF UBIQUITINYLATION PROTEINS | 39 | 5.38e-01 | -5.70e-02 | 0.99200 |
| REACTOME CIPROFLOXACIN ADME | 5 | 5.38e-01 | -1.59e-01 | 0.99200 |
| REACTOME SIGNALING BY ALK | 26 | 5.38e-01 | 6.98e-02 | 0.99200 |
| REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | 14 | 5.39e-01 | -9.49e-02 | 0.99200 |
| REACTOME EFFECTS OF PIP2 HYDROLYSIS | 26 | 5.40e-01 | 6.95e-02 | 0.99200 |
| REACTOME TRAIL SIGNALING | 8 | 5.43e-01 | 1.24e-01 | 0.99200 |
| REACTOME RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA | 7 | 5.44e-01 | 1.32e-01 | 0.99200 |
| REACTOME SIGNALING BY PTK6 | 54 | 5.44e-01 | -4.77e-02 | 0.99200 |
| REACTOME RHOBTB GTPASE CYCLE | 34 | 5.45e-01 | -5.99e-02 | 0.99200 |
| REACTOME PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1 | 9 | 5.47e-01 | -1.16e-01 | 0.99200 |
| REACTOME NUCLEAR ENVELOPE BREAKDOWN | 52 | 5.47e-01 | -4.83e-02 | 0.99200 |
| REACTOME ACTIVATION OF RAC1 | 12 | 5.47e-01 | -1.00e-01 | 0.99200 |
| REACTOME DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA | 77 | 5.48e-01 | 3.96e-02 | 0.99200 |
| REACTOME REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION | 9 | 5.48e-01 | -1.16e-01 | 0.99200 |
| REACTOME ARACHIDONIC ACID METABOLISM | 57 | 5.49e-01 | -4.59e-02 | 0.99200 |
| REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1 | 31 | 5.50e-01 | 6.21e-02 | 0.99200 |
| REACTOME SYNTHESIS OF 12 EICOSATETRAENOIC ACID DERIVATIVES | 7 | 5.51e-01 | -1.30e-01 | 0.99200 |
| REACTOME NEGATIVE REGULATION OF FLT3 | 15 | 5.52e-01 | -8.87e-02 | 0.99200 |
| REACTOME ER QUALITY CONTROL COMPARTMENT ERQC | 21 | 5.53e-01 | 7.49e-02 | 0.99200 |
| REACTOME TRAFFICKING OF AMPA RECEPTORS | 29 | 5.53e-01 | 6.37e-02 | 0.99200 |
| REACTOME ESTROGEN DEPENDENT GENE EXPRESSION | 140 | 5.53e-01 | 2.90e-02 | 0.99200 |
| REACTOME SIGNALING BY ERBB2 ECD MUTANTS | 16 | 5.54e-01 | 8.54e-02 | 0.99200 |
| REACTOME RNA POLYMERASE III CHAIN ELONGATION | 18 | 5.55e-01 | 8.03e-02 | 0.99200 |
| REACTOME SIGNALING BY HIPPO | 19 | 5.56e-01 | 7.81e-02 | 0.99200 |
| REACTOME TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7 | 12 | 5.56e-01 | -9.81e-02 | 0.99200 |
| REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS | 43 | 5.57e-01 | -5.18e-02 | 0.99200 |
| REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION | 6 | 5.57e-01 | 1.38e-01 | 0.99200 |
| REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | 17 | 5.58e-01 | -8.21e-02 | 0.99200 |
| REACTOME TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY | 30 | 5.58e-01 | -6.18e-02 | 0.99200 |
| REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION | 145 | 5.58e-01 | -2.82e-02 | 0.99200 |
| REACTOME ALK MUTANTS BIND TKIS | 12 | 5.58e-01 | -9.76e-02 | 0.99200 |
| REACTOME METABOLISM OF STEROID HORMONES | 35 | 5.59e-01 | -5.70e-02 | 0.99200 |
| REACTOME COHESIN LOADING ONTO CHROMATIN | 8 | 5.59e-01 | -1.19e-01 | 0.99200 |
| REACTOME SIGNAL TRANSDUCTION BY L1 | 20 | 5.60e-01 | -7.52e-02 | 0.99200 |
| REACTOME DEFECTIVE GALNT3 CAUSES HFTC | 16 | 5.62e-01 | -8.37e-02 | 0.99200 |
| REACTOME ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES | 59 | 5.62e-01 | 4.36e-02 | 0.99200 |
| REACTOME FRUCTOSE METABOLISM | 7 | 5.63e-01 | -1.26e-01 | 0.99200 |
| REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1 | 16 | 5.64e-01 | 8.32e-02 | 0.99200 |
| REACTOME SIGNALING BY RETINOIC ACID | 41 | 5.64e-01 | 5.20e-02 | 0.99200 |
| REACTOME MITOTIC G2 G2 M PHASES | 194 | 5.65e-01 | -2.40e-02 | 0.99200 |
| REACTOME ORGANIC ANION TRANSPORTERS | 10 | 5.66e-01 | 1.05e-01 | 0.99200 |
| REACTOME MRNA SPLICING MINOR PATHWAY | 49 | 5.67e-01 | -4.72e-02 | 0.99200 |
| REACTOME NEGATIVE REGULATION OF MET ACTIVITY | 20 | 5.68e-01 | -7.38e-02 | 0.99200 |
| REACTOME RHOC GTPASE CYCLE | 71 | 5.68e-01 | -3.92e-02 | 0.99200 |
| REACTOME CELLULAR RESPONSE TO HYPOXIA | 74 | 5.68e-01 | -3.84e-02 | 0.99200 |
| REACTOME FRS MEDIATED FGFR2 SIGNALING | 24 | 5.68e-01 | 6.73e-02 | 0.99200 |
| REACTOME MTOR SIGNALLING | 40 | 5.69e-01 | 5.21e-02 | 0.99200 |
| REACTOME G0 AND EARLY G1 | 27 | 5.69e-01 | 6.33e-02 | 0.99200 |
| REACTOME ACYL CHAIN REMODELLING OF PE | 29 | 5.69e-01 | 6.10e-02 | 0.99200 |
| REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | 23 | 5.70e-01 | 6.84e-02 | 0.99200 |
| REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | 111 | 5.71e-01 | 3.12e-02 | 0.99200 |
| REACTOME POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE | 25 | 5.71e-01 | -6.55e-02 | 0.99200 |
| REACTOME CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY | 25 | 5.71e-01 | 6.54e-02 | 0.99200 |
| REACTOME INTERLEUKIN RECEPTOR SHC SIGNALING | 24 | 5.72e-01 | 6.67e-02 | 0.99200 |
| REACTOME ERBB2 ACTIVATES PTK6 SIGNALING | 13 | 5.72e-01 | -9.04e-02 | 0.99200 |
| REACTOME RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS | 5 | 5.73e-01 | -1.46e-01 | 0.99200 |
| REACTOME ARMS MEDIATED ACTIVATION | 7 | 5.73e-01 | -1.23e-01 | 0.99200 |
| REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS | 34 | 5.73e-01 | -5.58e-02 | 0.99200 |
| REACTOME INTERLEUKIN 12 FAMILY SIGNALING | 53 | 5.74e-01 | -4.46e-02 | 0.99200 |
| REACTOME PI3K AKT ACTIVATION | 9 | 5.75e-01 | -1.08e-01 | 0.99200 |
| REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES | 37 | 5.76e-01 | 5.32e-02 | 0.99200 |
| REACTOME DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE | 30 | 5.76e-01 | -5.91e-02 | 0.99200 |
| REACTOME PI METABOLISM | 79 | 5.76e-01 | 3.64e-02 | 0.99200 |
| REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING | 25 | 5.78e-01 | 6.44e-02 | 0.99200 |
| REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE | 11 | 5.78e-01 | -9.70e-02 | 0.99200 |
| REACTOME SYNDECAN INTERACTIONS | 26 | 5.78e-01 | -6.29e-02 | 0.99200 |
| REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | 62 | 5.79e-01 | -4.08e-02 | 0.99200 |
| REACTOME G ALPHA 12 13 SIGNALLING EVENTS | 74 | 5.79e-01 | 3.73e-02 | 0.99200 |
| REACTOME SUMOYLATION OF INTRACELLULAR RECEPTORS | 29 | 5.80e-01 | -5.94e-02 | 0.99200 |
| REACTOME C TYPE LECTIN RECEPTORS CLRS | 136 | 5.80e-01 | -2.75e-02 | 0.99200 |
| REACTOME NCAM1 INTERACTIONS | 41 | 5.80e-01 | 5.00e-02 | 0.99200 |
| REACTOME SUMOYLATION OF TRANSCRIPTION FACTORS | 20 | 5.80e-01 | -7.14e-02 | 0.99200 |
| REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 | 54 | 5.81e-01 | -4.34e-02 | 0.99200 |
| REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA | 11 | 5.81e-01 | -9.61e-02 | 0.99200 |
| REACTOME RESOLUTION OF D LOOP STRUCTURES | 33 | 5.82e-01 | -5.54e-02 | 0.99200 |
| REACTOME SYNTHESIS OF PG | 8 | 5.82e-01 | 1.12e-01 | 0.99200 |
| REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 44 | 5.83e-01 | -4.78e-02 | 0.99200 |
| REACTOME SIGNALING BY TGFB FAMILY MEMBERS | 119 | 5.83e-01 | -2.91e-02 | 0.99200 |
| REACTOME REGULATION OF IFNG SIGNALING | 14 | 5.84e-01 | -8.46e-02 | 0.99200 |
| REACTOME DRUG ADME | 103 | 5.84e-01 | 3.12e-02 | 0.99200 |
| REACTOME DEFECTIVE CSF2RB CAUSES SMDP5 | 7 | 5.84e-01 | -1.19e-01 | 0.99200 |
| REACTOME DEFECTIVE B4GALT1 CAUSES B4GALT1 CDG CDG 2D | 8 | 5.85e-01 | -1.12e-01 | 0.99200 |
| REACTOME ACTIVATION OF NIMA KINASES NEK9 NEK6 NEK7 | 7 | 5.85e-01 | 1.19e-01 | 0.99200 |
| REACTOME DEPOLYMERISATION OF THE NUCLEAR LAMINA | 14 | 5.85e-01 | -8.42e-02 | 0.99200 |
| REACTOME FREE FATTY ACID RECEPTORS | 5 | 5.85e-01 | 1.41e-01 | 0.99200 |
| REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS | 6 | 5.85e-01 | 1.29e-01 | 0.99200 |
| REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS | 83 | 5.87e-01 | 3.44e-02 | 0.99200 |
| REACTOME IRS MEDIATED SIGNALLING | 47 | 5.88e-01 | 4.57e-02 | 0.99200 |
| REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY | 5 | 5.88e-01 | -1.40e-01 | 0.99200 |
| REACTOME PYRIMIDINE CATABOLISM | 12 | 5.88e-01 | -9.03e-02 | 0.99200 |
| REACTOME VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS | 42 | 5.88e-01 | -4.83e-02 | 0.99200 |
| REACTOME CD28 DEPENDENT VAV1 PATHWAY | 11 | 5.89e-01 | 9.40e-02 | 0.99200 |
| REACTOME ACTIVATION OF SMO | 18 | 5.89e-01 | -7.35e-02 | 0.99200 |
| REACTOME MYOGENESIS | 29 | 5.89e-01 | 5.79e-02 | 0.99200 |
| REACTOME RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION | 6 | 5.90e-01 | 1.27e-01 | 0.99200 |
| REACTOME SEROTONIN NEUROTRANSMITTER RELEASE CYCLE | 17 | 5.90e-01 | -7.54e-02 | 0.99200 |
| REACTOME OPIOID SIGNALLING | 89 | 5.90e-01 | 3.30e-02 | 0.99200 |
| REACTOME HATS ACETYLATE HISTONES | 129 | 5.90e-01 | 2.74e-02 | 0.99200 |
| REACTOME SYNTHESIS OF PA | 38 | 5.92e-01 | -5.03e-02 | 0.99200 |
| REACTOME RUNX2 REGULATES BONE DEVELOPMENT | 29 | 5.92e-01 | 5.76e-02 | 0.99200 |
| REACTOME ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA | 15 | 5.92e-01 | -7.99e-02 | 0.99200 |
| REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | 36 | 5.92e-01 | -5.16e-02 | 0.99200 |
| REACTOME CREB3 FACTORS ACTIVATE GENES | 8 | 5.93e-01 | -1.09e-01 | 0.99200 |
| REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX | 19 | 5.93e-01 | 7.08e-02 | 0.99200 |
| REACTOME DEATH RECEPTOR SIGNALING | 143 | 5.93e-01 | 2.59e-02 | 0.99200 |
| REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION | 8 | 5.93e-01 | 1.09e-01 | 0.99200 |
| REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | 13 | 5.94e-01 | -8.55e-02 | 0.99200 |
| REACTOME REGULATION OF TP53 EXPRESSION AND DEGRADATION | 37 | 5.94e-01 | 5.07e-02 | 0.99200 |
| REACTOME SIGNALING BY FGFR2 | 72 | 5.94e-01 | 3.64e-02 | 0.99200 |
| REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | 13 | 5.95e-01 | 8.52e-02 | 0.99200 |
| REACTOME SARS COV 1 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS | 16 | 5.97e-01 | -7.64e-02 | 0.99200 |
| REACTOME TELOMERE EXTENSION BY TELOMERASE | 22 | 5.97e-01 | -6.52e-02 | 0.99200 |
| REACTOME INITIAL TRIGGERING OF COMPLEMENT | 21 | 5.97e-01 | 6.67e-02 | 0.99200 |
| REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | 89 | 5.97e-01 | 3.24e-02 | 0.99200 |
| REACTOME TBC RABGAPS | 40 | 5.99e-01 | 4.80e-02 | 0.99200 |
| REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS | 12 | 5.99e-01 | 8.76e-02 | 0.99200 |
| REACTOME SIGNALING BY NOTCH3 | 48 | 5.99e-01 | 4.38e-02 | 0.99200 |
| REACTOME RHO GTPASES ACTIVATE WASPS AND WAVES | 34 | 5.99e-01 | -5.21e-02 | 0.99200 |
| REACTOME REGULATION OF BETA CELL DEVELOPMENT | 41 | 6.00e-01 | 4.74e-02 | 0.99200 |
| REACTOME MUSCARINIC ACETYLCHOLINE RECEPTORS | 5 | 6.00e-01 | -1.36e-01 | 0.99200 |
| REACTOME CYTOPROTECTION BY HMOX1 | 59 | 6.00e-01 | -3.95e-02 | 0.99200 |
| REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | 17 | 6.00e-01 | -7.34e-02 | 0.99200 |
| REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES | 77 | 6.01e-01 | -3.44e-02 | 0.99200 |
| REACTOME MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS | 13 | 6.02e-01 | -8.36e-02 | 0.99200 |
| REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | 20 | 6.03e-01 | 6.72e-02 | 0.99200 |
| REACTOME ECM PROTEOGLYCANS | 73 | 6.04e-01 | 3.51e-02 | 0.99200 |
| REACTOME PHYSIOLOGICAL FACTORS | 14 | 6.04e-01 | 8.00e-02 | 0.99200 |
| REACTOME TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE | 20 | 6.05e-01 | 6.69e-02 | 0.99200 |
| REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL | 58 | 6.05e-01 | 3.92e-02 | 0.99200 |
| REACTOME INFLUENZA INFECTION | 149 | 6.07e-01 | -2.44e-02 | 0.99200 |
| REACTOME SUPPRESSION OF PHAGOSOMAL MATURATION | 13 | 6.07e-01 | -8.24e-02 | 0.99200 |
| REACTOME UNWINDING OF DNA | 12 | 6.07e-01 | 8.57e-02 | 0.99200 |
| REACTOME NEF MEDIATED CD4 DOWN REGULATION | 9 | 6.07e-01 | 9.90e-02 | 0.99200 |
| REACTOME G2 PHASE | 5 | 6.07e-01 | 1.33e-01 | 0.99200 |
| REACTOME VITAMIN C ASCORBATE METABOLISM | 8 | 6.07e-01 | -1.05e-01 | 0.99200 |
| REACTOME ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY | 10 | 6.08e-01 | -9.35e-02 | 0.99200 |
| REACTOME DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM | 38 | 6.09e-01 | -4.80e-02 | 0.99200 |
| REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING | 28 | 6.10e-01 | -5.58e-02 | 0.99200 |
| REACTOME APOPTOTIC FACTOR MEDIATED RESPONSE | 19 | 6.10e-01 | -6.76e-02 | 0.99200 |
| REACTOME FOLDING OF ACTIN BY CCT TRIC | 10 | 6.10e-01 | 9.31e-02 | 0.99200 |
| REACTOME SELECTIVE AUTOPHAGY | 79 | 6.10e-01 | 3.32e-02 | 0.99200 |
| REACTOME CHOLINE CATABOLISM | 6 | 6.10e-01 | 1.20e-01 | 0.99200 |
| REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | 21 | 6.11e-01 | -6.41e-02 | 0.99200 |
| REACTOME INTERLEUKIN 35 SIGNALLING | 12 | 6.11e-01 | -8.47e-02 | 0.99200 |
| REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | 14 | 6.12e-01 | 7.83e-02 | 0.99200 |
| REACTOME KERATAN SULFATE KERATIN METABOLISM | 34 | 6.12e-01 | -5.02e-02 | 0.99200 |
| REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS | 6 | 6.13e-01 | -1.19e-01 | 0.99200 |
| REACTOME EICOSANOIDS | 12 | 6.14e-01 | 8.42e-02 | 0.99200 |
| REACTOME ARACHIDONATE PRODUCTION FROM DAG | 5 | 6.14e-01 | 1.30e-01 | 0.99200 |
| REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | 30 | 6.14e-01 | -5.31e-02 | 0.99200 |
| REACTOME DEGRADATION OF AXIN | 54 | 6.15e-01 | -3.96e-02 | 0.99200 |
| REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING | 6 | 6.15e-01 | -1.19e-01 | 0.99200 |
| REACTOME ERBB2 REGULATES CELL MOTILITY | 15 | 6.15e-01 | -7.49e-02 | 0.99200 |
| REACTOME MISCELLANEOUS SUBSTRATES | 12 | 6.16e-01 | -8.36e-02 | 0.99200 |
| REACTOME ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS | 10 | 6.16e-01 | -9.15e-02 | 0.99200 |
| REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS | 161 | 6.17e-01 | 2.29e-02 | 0.99200 |
| REACTOME SIGNAL AMPLIFICATION | 33 | 6.17e-01 | 5.03e-02 | 0.99200 |
| REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS | 68 | 6.17e-01 | 3.51e-02 | 0.99200 |
| REACTOME TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS | 52 | 6.18e-01 | -4.00e-02 | 0.99200 |
| REACTOME HISTIDINE CATABOLISM | 8 | 6.18e-01 | -1.02e-01 | 0.99200 |
| REACTOME NEUREXINS AND NEUROLIGINS | 51 | 6.18e-01 | -4.03e-02 | 0.99200 |
| REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | 15 | 6.19e-01 | -7.41e-02 | 0.99200 |
| REACTOME PEPTIDE HORMONE METABOLISM | 84 | 6.20e-01 | 3.13e-02 | 0.99200 |
| REACTOME INTERLEUKIN 15 SIGNALING | 13 | 6.21e-01 | -7.92e-02 | 0.99200 |
| REACTOME SIGNALING BY HEDGEHOG | 148 | 6.22e-01 | -2.34e-02 | 0.99200 |
| REACTOME SEMA4D IN SEMAPHORIN SIGNALING | 24 | 6.23e-01 | 5.80e-02 | 0.99200 |
| REACTOME OTHER INTERLEUKIN SIGNALING | 24 | 6.25e-01 | 5.77e-02 | 0.99200 |
| REACTOME DIGESTION OF DIETARY CARBOHYDRATE | 6 | 6.25e-01 | -1.15e-01 | 0.99200 |
| REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL | 13 | 6.25e-01 | -7.83e-02 | 0.99200 |
| REACTOME TLR3 MEDIATED TICAM1 DEPENDENT PROGRAMMED CELL DEATH | 6 | 6.26e-01 | -1.15e-01 | 0.99200 |
| REACTOME CD22 MEDIATED BCR REGULATION | 5 | 6.26e-01 | -1.26e-01 | 0.99200 |
| REACTOME ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS | 11 | 6.28e-01 | 8.44e-02 | 0.99200 |
| REACTOME SYNTHESIS OF GDP MANNOSE | 5 | 6.28e-01 | -1.25e-01 | 0.99200 |
| REACTOME UB SPECIFIC PROCESSING PROTEASES | 187 | 6.29e-01 | -2.05e-02 | 0.99200 |
| REACTOME PTEN REGULATION | 135 | 6.30e-01 | -2.40e-02 | 0.99200 |
| REACTOME EICOSANOID LIGAND BINDING RECEPTORS | 14 | 6.30e-01 | 7.44e-02 | 0.99200 |
| REACTOME ACETYLCHOLINE REGULATES INSULIN SECRETION | 10 | 6.30e-01 | 8.80e-02 | 0.99200 |
| REACTOME SIGNALING BY ROBO RECEPTORS | 206 | 6.30e-01 | 1.95e-02 | 0.99200 |
| REACTOME ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT | 23 | 6.30e-01 | 5.80e-02 | 0.99200 |
| REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS | 11 | 6.30e-01 | -8.38e-02 | 0.99200 |
| REACTOME PHASE 0 RAPID DEPOLARISATION | 31 | 6.31e-01 | 4.98e-02 | 0.99200 |
| REACTOME G BETA GAMMA SIGNALLING THROUGH CDC42 | 19 | 6.32e-01 | -6.36e-02 | 0.99200 |
| REACTOME CA2 PATHWAY | 62 | 6.33e-01 | 3.51e-02 | 0.99200 |
| REACTOME REGULATION OF INSULIN SECRETION | 77 | 6.34e-01 | 3.14e-02 | 0.99200 |
| REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP | 104 | 6.34e-01 | 2.70e-02 | 0.99200 |
| REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | 14 | 6.34e-01 | -7.35e-02 | 0.99200 |
| REACTOME PI3K EVENTS IN ERBB4 SIGNALING | 10 | 6.34e-01 | -8.69e-02 | 0.99200 |
| REACTOME CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2 | 11 | 6.34e-01 | -8.28e-02 | 0.99200 |
| REACTOME PREGNENOLONE BIOSYNTHESIS | 12 | 6.35e-01 | -7.91e-02 | 0.99200 |
| REACTOME REGULATION OF NPAS4 MRNA TRANSLATION | 9 | 6.38e-01 | -9.06e-02 | 0.99500 |
| REACTOME DNA DOUBLE STRAND BREAK RESPONSE | 74 | 6.39e-01 | 3.16e-02 | 0.99500 |
| REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | 37 | 6.41e-01 | -4.42e-02 | 0.99500 |
| REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE GIP | 12 | 6.42e-01 | -7.75e-02 | 0.99500 |
| REACTOME SIGNALING BY FGFR | 85 | 6.42e-01 | 2.92e-02 | 0.99500 |
| REACTOME SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX | 15 | 6.42e-01 | 6.93e-02 | 0.99500 |
| REACTOME METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES | 33 | 6.42e-01 | 4.67e-02 | 0.99500 |
| REACTOME SIGNALING BY INTERLEUKINS | 444 | 6.44e-01 | 1.28e-02 | 0.99500 |
| REACTOME CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE | 49 | 6.44e-01 | 3.81e-02 | 0.99500 |
| REACTOME GLYCOSPHINGOLIPID METABOLISM | 39 | 6.45e-01 | -4.27e-02 | 0.99500 |
| REACTOME VLDL ASSEMBLY | 5 | 6.46e-01 | 1.19e-01 | 0.99500 |
| REACTOME WNT MEDIATED ACTIVATION OF DVL | 8 | 6.46e-01 | -9.38e-02 | 0.99500 |
| REACTOME SIGNALING BY THE B CELL RECEPTOR BCR | 106 | 6.46e-01 | 2.58e-02 | 0.99500 |
| REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH | 62 | 6.47e-01 | 3.37e-02 | 0.99500 |
| REACTOME NEF MEDIATED CD8 DOWN REGULATION | 7 | 6.47e-01 | 1.00e-01 | 0.99500 |
| REACTOME RECEPTOR MEDIATED MITOPHAGY | 10 | 6.49e-01 | -8.32e-02 | 0.99500 |
| REACTOME REGULATION OF TP53 ACTIVITY | 156 | 6.51e-01 | -2.10e-02 | 0.99500 |
| REACTOME HS GAG BIOSYNTHESIS | 28 | 6.52e-01 | -4.93e-02 | 0.99500 |
| REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION | 20 | 6.52e-01 | 5.82e-02 | 0.99500 |
| REACTOME FGFR1B LIGAND BINDING AND ACTIVATION | 6 | 6.52e-01 | -1.06e-01 | 0.99500 |
| REACTOME DOWNREGULATION OF ERBB4 SIGNALING | 9 | 6.54e-01 | -8.64e-02 | 0.99500 |
| REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | 24 | 6.54e-01 | -5.29e-02 | 0.99500 |
| REACTOME G PROTEIN MEDIATED EVENTS | 53 | 6.54e-01 | 3.56e-02 | 0.99500 |
| REACTOME FOXO MEDIATED TRANSCRIPTION | 65 | 6.56e-01 | 3.20e-02 | 0.99500 |
| REACTOME UPTAKE AND FUNCTION OF ANTHRAX TOXINS | 11 | 6.58e-01 | 7.72e-02 | 0.99500 |
| REACTOME IRAK4 DEFICIENCY TLR2 4 | 17 | 6.60e-01 | 6.17e-02 | 0.99500 |
| REACTOME DEFECTIVE F9 ACTIVATION | 5 | 6.60e-01 | 1.13e-01 | 0.99500 |
| REACTOME CELLULAR RESPONSE TO HEAT STRESS | 99 | 6.61e-01 | -2.55e-02 | 0.99500 |
| REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR | 79 | 6.61e-01 | -2.86e-02 | 0.99500 |
| REACTOME ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS | 5 | 6.61e-01 | 1.13e-01 | 0.99500 |
| REACTOME NEUROTRANSMITTER RELEASE CYCLE | 48 | 6.61e-01 | 3.66e-02 | 0.99500 |
| REACTOME HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR IN THE PRESENCE OF LIGAND | 55 | 6.61e-01 | -3.42e-02 | 0.99500 |
| REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | 16 | 6.61e-01 | 6.33e-02 | 0.99500 |
| REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN | 32 | 6.62e-01 | -4.47e-02 | 0.99500 |
| REACTOME PRE NOTCH EXPRESSION AND PROCESSING | 112 | 6.62e-01 | 2.39e-02 | 0.99500 |
| REACTOME BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA | 6 | 6.64e-01 | 1.02e-01 | 0.99500 |
| REACTOME GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION | 30 | 6.65e-01 | 4.57e-02 | 0.99500 |
| REACTOME SARS COV 2 HOST INTERACTIONS | 191 | 6.65e-01 | -1.82e-02 | 0.99500 |
| REACTOME CONSTITUTIVE SIGNALING BY EGFRVIII | 15 | 6.65e-01 | 6.45e-02 | 0.99500 |
| REACTOME POTENTIAL THERAPEUTICS FOR SARS | 92 | 6.66e-01 | -2.60e-02 | 0.99500 |
| REACTOME COLLAGEN CHAIN TRIMERIZATION | 42 | 6.67e-01 | 3.84e-02 | 0.99500 |
| REACTOME FATTY ACIDS | 15 | 6.67e-01 | -6.42e-02 | 0.99500 |
| REACTOME SIGNALING BY NOTCH4 | 80 | 6.68e-01 | -2.78e-02 | 0.99500 |
| REACTOME CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION | 11 | 6.68e-01 | 7.47e-02 | 0.99500 |
| REACTOME FRS MEDIATED FGFR3 SIGNALING | 19 | 6.68e-01 | -5.67e-02 | 0.99500 |
| REACTOME FCGR3A MEDIATED IL10 SYNTHESIS | 36 | 6.69e-01 | 4.11e-02 | 0.99500 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE | 5 | 6.70e-01 | -1.10e-01 | 0.99500 |
| REACTOME PROTEIN REPAIR | 6 | 6.71e-01 | -1.00e-01 | 0.99500 |
| REACTOME ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS | 20 | 6.71e-01 | 5.49e-02 | 0.99500 |
| REACTOME BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA | 5 | 6.72e-01 | 1.09e-01 | 0.99500 |
| REACTOME DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15 | 8 | 6.73e-01 | -8.62e-02 | 0.99500 |
| REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R | 52 | 6.75e-01 | 3.36e-02 | 0.99500 |
| REACTOME PLASMA LIPOPROTEIN CLEARANCE | 37 | 6.75e-01 | 3.99e-02 | 0.99500 |
| REACTOME PI 3K CASCADE FGFR1 | 21 | 6.75e-01 | 5.28e-02 | 0.99500 |
| REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | 20 | 6.76e-01 | -5.40e-02 | 0.99500 |
| REACTOME CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS | 100 | 6.76e-01 | -2.42e-02 | 0.99500 |
| REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION | 35 | 6.76e-01 | -4.08e-02 | 0.99500 |
| REACTOME SENSING OF DNA DOUBLE STRAND BREAKS | 6 | 6.76e-01 | -9.84e-02 | 0.99500 |
| REACTOME DERMATAN SULFATE BIOSYNTHESIS | 10 | 6.77e-01 | 7.61e-02 | 0.99500 |
| REACTOME EPHRIN SIGNALING | 17 | 6.77e-01 | -5.83e-02 | 0.99500 |
| REACTOME PINK1 PRKN MEDIATED MITOPHAGY | 22 | 6.77e-01 | -5.13e-02 | 0.99500 |
| REACTOME INTERLEUKIN 7 SIGNALING | 31 | 6.78e-01 | -4.31e-02 | 0.99500 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS | 121 | 6.79e-01 | 2.18e-02 | 0.99500 |
| REACTOME PROCESSING OF INTRONLESS PRE MRNAS | 19 | 6.80e-01 | -5.47e-02 | 0.99500 |
| REACTOME TRANSLATION | 278 | 6.81e-01 | -1.43e-02 | 0.99500 |
| REACTOME STAT3 NUCLEAR EVENTS DOWNSTREAM OF ALK SIGNALING | 9 | 6.82e-01 | 7.89e-02 | 0.99500 |
| REACTOME IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS | 17 | 6.82e-01 | -5.74e-02 | 0.99500 |
| REACTOME VLDLR INTERNALISATION AND DEGRADATION | 16 | 6.83e-01 | 5.90e-02 | 0.99500 |
| REACTOME HYALURONAN BIOSYNTHESIS AND EXPORT | 5 | 6.83e-01 | 1.05e-01 | 0.99500 |
| REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE | 5 | 6.84e-01 | 1.05e-01 | 0.99500 |
| REACTOME MET RECEPTOR RECYCLING | 10 | 6.84e-01 | 7.43e-02 | 0.99500 |
| REACTOME NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 19 | 6.85e-01 | -5.37e-02 | 0.99500 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS | 5 | 6.86e-01 | -1.04e-01 | 0.99500 |
| REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | 10 | 6.86e-01 | 7.39e-02 | 0.99500 |
| REACTOME RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY | 14 | 6.86e-01 | 6.24e-02 | 0.99500 |
| REACTOME FGFR3B LIGAND BINDING AND ACTIVATION | 7 | 6.87e-01 | -8.81e-02 | 0.99500 |
| REACTOME PKA ACTIVATION IN GLUCAGON SIGNALLING | 17 | 6.87e-01 | -5.65e-02 | 0.99500 |
| REACTOME RESPIRATORY ELECTRON TRANSPORT | 90 | 6.87e-01 | 2.46e-02 | 0.99500 |
| REACTOME SEMA3A PAK DEPENDENT AXON REPULSION | 14 | 6.88e-01 | -6.21e-02 | 0.99500 |
| REACTOME RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA | 27 | 6.88e-01 | -4.46e-02 | 0.99500 |
| REACTOME LAMININ INTERACTIONS | 28 | 6.89e-01 | 4.37e-02 | 0.99500 |
| REACTOME LONG TERM POTENTIATION | 22 | 6.89e-01 | 4.93e-02 | 0.99500 |
| REACTOME ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY | 10 | 6.90e-01 | -7.29e-02 | 0.99500 |
| REACTOME REPRODUCTION | 136 | 6.91e-01 | 1.98e-02 | 0.99500 |
| REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | 24 | 6.92e-01 | -4.68e-02 | 0.99500 |
| REACTOME SIGNALING BY SCF KIT | 42 | 6.92e-01 | -3.53e-02 | 0.99500 |
| REACTOME RHOB GTPASE CYCLE | 67 | 6.93e-01 | -2.79e-02 | 0.99500 |
| REACTOME ENDOSOMAL VACUOLAR PATHWAY | 11 | 6.93e-01 | -6.88e-02 | 0.99500 |
| REACTOME FGFR2 ALTERNATIVE SPLICING | 27 | 6.93e-01 | 4.39e-02 | 0.99500 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST | 14 | 6.93e-01 | -6.10e-02 | 0.99500 |
| REACTOME REGULATION OF PTEN MRNA TRANSLATION | 9 | 6.93e-01 | -7.60e-02 | 0.99500 |
| REACTOME MUCOPOLYSACCHARIDOSES | 10 | 6.94e-01 | -7.19e-02 | 0.99500 |
| REACTOME DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS | 19 | 6.96e-01 | -5.18e-02 | 0.99500 |
| REACTOME ONCOGENIC MAPK SIGNALING | 79 | 6.97e-01 | 2.53e-02 | 0.99500 |
| REACTOME ACTIVATION OF C3 AND C5 | 6 | 6.99e-01 | 9.12e-02 | 0.99500 |
| REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | 15 | 7.01e-01 | 5.73e-02 | 0.99500 |
| REACTOME REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS | 15 | 7.01e-01 | 5.72e-02 | 0.99500 |
| REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION | 138 | 7.02e-01 | 1.89e-02 | 0.99500 |
| REACTOME TOXICITY OF BOTULINUM TOXIN TYPE D BOTD | 5 | 7.02e-01 | 9.88e-02 | 0.99500 |
| REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21 | 59 | 7.03e-01 | -2.87e-02 | 0.99500 |
| REACTOME COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC | 52 | 7.03e-01 | -3.06e-02 | 0.99500 |
| REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS | 17 | 7.03e-01 | -5.34e-02 | 0.99500 |
| REACTOME O LINKED GLYCOSYLATION OF MUCINS | 61 | 7.03e-01 | -2.82e-02 | 0.99500 |
| REACTOME NONCANONICAL ACTIVATION OF NOTCH3 | 8 | 7.04e-01 | -7.76e-02 | 0.99500 |
| REACTOME HEDGEHOG LIGAND BIOGENESIS | 64 | 7.04e-01 | 2.75e-02 | 0.99500 |
| REACTOME CLATHRIN MEDIATED ENDOCYTOSIS | 139 | 7.05e-01 | -1.86e-02 | 0.99500 |
| REACTOME PHOSPHOLIPID METABOLISM | 201 | 7.05e-01 | -1.55e-02 | 0.99500 |
| REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1 | 25 | 7.07e-01 | -4.35e-02 | 0.99500 |
| REACTOME RNA POLYMERASE III TRANSCRIPTION TERMINATION | 23 | 7.07e-01 | 4.53e-02 | 0.99500 |
| REACTOME HDL ASSEMBLY | 8 | 7.08e-01 | -7.66e-02 | 0.99500 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS | 9 | 7.08e-01 | 7.20e-02 | 0.99500 |
| REACTOME SIGNALING BY NOTCH1 | 69 | 7.08e-01 | 2.60e-02 | 0.99500 |
| REACTOME MET ACTIVATES RAS SIGNALING | 11 | 7.08e-01 | -6.51e-02 | 0.99500 |
| REACTOME PI3K EVENTS IN ERBB2 SIGNALING | 16 | 7.09e-01 | 5.39e-02 | 0.99500 |
| REACTOME INSULIN RECEPTOR RECYCLING | 29 | 7.09e-01 | -4.00e-02 | 0.99500 |
| REACTOME SHC MEDIATED CASCADE FGFR3 | 17 | 7.10e-01 | -5.21e-02 | 0.99500 |
| REACTOME REGULATION OF RUNX3 EXPRESSION AND ACTIVITY | 54 | 7.10e-01 | -2.92e-02 | 0.99500 |
| REACTOME CAMK IV MEDIATED PHOSPHORYLATION OF CREB | 10 | 7.11e-01 | 6.78e-02 | 0.99500 |
| REACTOME CHROMATIN MODIFYING ENZYMES | 252 | 7.12e-01 | -1.35e-02 | 0.99500 |
| REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | 122 | 7.12e-01 | 1.93e-02 | 0.99500 |
| REACTOME RHOT1 GTPASE CYCLE | 5 | 7.13e-01 | 9.50e-02 | 0.99500 |
| REACTOME NICOTINATE METABOLISM | 31 | 7.14e-01 | -3.80e-02 | 0.99500 |
| REACTOME LATE ENDOSOMAL MICROAUTOPHAGY | 33 | 7.14e-01 | -3.69e-02 | 0.99500 |
| REACTOME RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES TREGS | 9 | 7.15e-01 | 7.04e-02 | 0.99500 |
| REACTOME FGFR2C LIGAND BINDING AND ACTIVATION | 12 | 7.15e-01 | 6.10e-02 | 0.99500 |
| REACTOME MICRORNA MIRNA BIOGENESIS | 25 | 7.17e-01 | -4.18e-02 | 0.99500 |
| REACTOME SARS COV 2 TARGETS PDZ PROTEINS IN CELL CELL JUNCTION | 5 | 7.18e-01 | -9.33e-02 | 0.99500 |
| REACTOME MITOCHONDRIAL UNCOUPLING | 5 | 7.19e-01 | -9.30e-02 | 0.99500 |
| REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS | 299 | 7.19e-01 | -1.21e-02 | 0.99500 |
| REACTOME CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION | 24 | 7.20e-01 | -4.23e-02 | 0.99500 |
| REACTOME DISINHIBITION OF SNARE FORMATION | 5 | 7.20e-01 | -9.27e-02 | 0.99500 |
| REACTOME SOS MEDIATED SIGNALLING | 7 | 7.20e-01 | 7.82e-02 | 0.99500 |
| REACTOME PTK6 EXPRESSION | 5 | 7.20e-01 | -9.25e-02 | 0.99500 |
| REACTOME METHIONINE SALVAGE PATHWAY | 6 | 7.20e-01 | -8.44e-02 | 0.99500 |
| REACTOME CREB PHOSPHORYLATION | 6 | 7.21e-01 | -8.43e-02 | 0.99500 |
| REACTOME DARPP 32 EVENTS | 24 | 7.21e-01 | -4.22e-02 | 0.99500 |
| REACTOME ATTENUATION PHASE | 27 | 7.22e-01 | -3.96e-02 | 0.99500 |
| REACTOME BILE ACID AND BILE SALT METABOLISM | 45 | 7.22e-01 | -3.07e-02 | 0.99500 |
| REACTOME INTERLEUKIN 2 FAMILY SIGNALING | 40 | 7.22e-01 | -3.25e-02 | 0.99500 |
| REACTOME TRANSPORT OF ORGANIC ANIONS | 10 | 7.22e-01 | 6.49e-02 | 0.99500 |
| REACTOME EGFR DOWNREGULATION | 30 | 7.23e-01 | -3.74e-02 | 0.99500 |
| REACTOME TRYPTOPHAN CATABOLISM | 14 | 7.25e-01 | 5.44e-02 | 0.99700 |
| REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER | 18 | 7.26e-01 | 4.76e-02 | 0.99800 |
| REACTOME COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM | 21 | 7.28e-01 | 4.39e-02 | 0.99800 |
| REACTOME RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR | 19 | 7.28e-01 | 4.61e-02 | 0.99800 |
| REACTOME SYNTHESIS OF UDP N ACETYL GLUCOSAMINE | 7 | 7.28e-01 | 7.58e-02 | 0.99800 |
| REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | 13 | 7.29e-01 | 5.54e-02 | 0.99800 |
| REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | 11 | 7.30e-01 | -6.02e-02 | 0.99800 |
| REACTOME SIGNALING BY INSULIN RECEPTOR | 80 | 7.32e-01 | 2.22e-02 | 0.99800 |
| REACTOME SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS | 12 | 7.32e-01 | -5.71e-02 | 0.99800 |
| REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING | 33 | 7.33e-01 | 3.43e-02 | 0.99800 |
| REACTOME RAS PROCESSING | 22 | 7.33e-01 | -4.20e-02 | 0.99800 |
| REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY | 72 | 7.33e-01 | -2.32e-02 | 0.99800 |
| REACTOME NONHOMOLOGOUS END JOINING NHEJ | 64 | 7.33e-01 | 2.46e-02 | 0.99800 |
| REACTOME INACTIVATION OF CDC42 AND RAC1 | 8 | 7.34e-01 | 6.93e-02 | 0.99800 |
| REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | 16 | 7.36e-01 | 4.88e-02 | 0.99800 |
| REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING | 34 | 7.36e-01 | -3.34e-02 | 0.99800 |
| REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK | 28 | 7.36e-01 | 3.68e-02 | 0.99800 |
| REACTOME DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A | 5 | 7.36e-01 | -8.70e-02 | 0.99800 |
| REACTOME SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL | 8 | 7.36e-01 | -6.87e-02 | 0.99800 |
| REACTOME AQUAPORIN MEDIATED TRANSPORT | 51 | 7.37e-01 | -2.72e-02 | 0.99800 |
| REACTOME METAL ION SLC TRANSPORTERS | 23 | 7.37e-01 | -4.04e-02 | 0.99800 |
| REACTOME MITOTIC PROPHASE | 134 | 7.40e-01 | 1.66e-02 | 0.99800 |
| REACTOME MET ACTIVATES PTK2 SIGNALING | 30 | 7.41e-01 | -3.49e-02 | 0.99800 |
| REACTOME ENDOGENOUS STEROLS | 26 | 7.44e-01 | -3.71e-02 | 0.99800 |
| REACTOME DISEASES ASSOCIATED WITH SURFACTANT METABOLISM | 9 | 7.44e-01 | -6.28e-02 | 0.99800 |
| REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | 111 | 7.45e-01 | 1.79e-02 | 0.99800 |
| REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM | 688 | 7.45e-01 | -7.27e-03 | 0.99800 |
| REACTOME PROCESSING OF DNA DOUBLE STRAND BREAK ENDS | 93 | 7.48e-01 | 1.93e-02 | 0.99800 |
| REACTOME TNFR1 INDUCED PROAPOPTOTIC SIGNALING | 23 | 7.48e-01 | 3.86e-02 | 0.99800 |
| REACTOME E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS | 58 | 7.50e-01 | -2.42e-02 | 0.99800 |
| REACTOME RIP MEDIATED NFKB ACTIVATION VIA ZBP1 | 16 | 7.51e-01 | 4.57e-02 | 0.99800 |
| REACTOME METABOLISM OF FOLATE AND PTERINES | 17 | 7.51e-01 | -4.44e-02 | 0.99800 |
| REACTOME PHOSPHORYLATION OF EMI1 | 6 | 7.52e-01 | -7.46e-02 | 0.99800 |
| REACTOME PARASITE INFECTION | 57 | 7.52e-01 | 2.42e-02 | 0.99800 |
| REACTOME RUNX2 REGULATES CHONDROCYTE MATURATION | 5 | 7.52e-01 | 8.15e-02 | 0.99800 |
| REACTOME BASE EXCISION REPAIR | 87 | 7.53e-01 | 1.95e-02 | 0.99800 |
| REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | 86 | 7.53e-01 | -1.96e-02 | 0.99800 |
| REACTOME SYNTHESIS OF PI | 5 | 7.54e-01 | 8.10e-02 | 0.99800 |
| REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER | 28 | 7.56e-01 | 3.40e-02 | 0.99800 |
| REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING | 45 | 7.57e-01 | -2.67e-02 | 0.99800 |
| REACTOME PI 3K CASCADE FGFR4 | 19 | 7.57e-01 | 4.10e-02 | 0.99800 |
| REACTOME TRANSPORT OF RCBL WITHIN THE BODY | 8 | 7.57e-01 | -6.31e-02 | 0.99800 |
| REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | 13 | 7.57e-01 | -4.95e-02 | 0.99800 |
| REACTOME COBALAMIN CBL METABOLISM | 7 | 7.57e-01 | -6.75e-02 | 0.99800 |
| REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX | 36 | 7.57e-01 | -2.98e-02 | 0.99800 |
| REACTOME SYNTHESIS OF PIPS AT THE ER MEMBRANE | 5 | 7.58e-01 | -7.97e-02 | 0.99800 |
| REACTOME PLATELET SENSITIZATION BY LDL | 17 | 7.58e-01 | -4.31e-02 | 0.99800 |
| REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING | 30 | 7.58e-01 | -3.25e-02 | 0.99800 |
| REACTOME SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS | 43 | 7.59e-01 | 2.70e-02 | 0.99800 |
| REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | 11 | 7.60e-01 | 5.32e-02 | 0.99800 |
| REACTOME RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES | 16 | 7.60e-01 | 4.41e-02 | 0.99800 |
| REACTOME MITOPHAGY | 28 | 7.61e-01 | -3.33e-02 | 0.99800 |
| REACTOME CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY | 84 | 7.61e-01 | 1.92e-02 | 0.99800 |
| REACTOME O LINKED GLYCOSYLATION | 109 | 7.61e-01 | 1.69e-02 | 0.99800 |
| REACTOME METABOLISM OF PORPHYRINS | 26 | 7.61e-01 | -3.45e-02 | 0.99800 |
| REACTOME CELL JUNCTION ORGANIZATION | 89 | 7.61e-01 | -1.86e-02 | 0.99800 |
| REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | 39 | 7.61e-01 | -2.81e-02 | 0.99800 |
| REACTOME RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION | 8 | 7.62e-01 | 6.18e-02 | 0.99800 |
| REACTOME RHO GTPASES ACTIVATE ROCKS | 19 | 7.62e-01 | -4.01e-02 | 0.99800 |
| REACTOME ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY | 5 | 7.63e-01 | 7.79e-02 | 0.99800 |
| REACTOME PROLONGED ERK ACTIVATION EVENTS | 14 | 7.64e-01 | -4.64e-02 | 0.99800 |
| REACTOME MET ACTIVATES RAP1 AND RAC1 | 11 | 7.64e-01 | -5.22e-02 | 0.99800 |
| REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | 16 | 7.64e-01 | 4.33e-02 | 0.99800 |
| REACTOME NUCLEAR SIGNALING BY ERBB4 | 32 | 7.65e-01 | -3.05e-02 | 0.99800 |
| REACTOME RNA POLYMERASE I TRANSCRIPTION TERMINATION | 30 | 7.66e-01 | -3.14e-02 | 0.99800 |
| REACTOME INTERFERON GAMMA SIGNALING | 88 | 7.66e-01 | -1.84e-02 | 0.99800 |
| REACTOME SIGNALING BY PDGF | 57 | 7.68e-01 | -2.26e-02 | 0.99800 |
| REACTOME UBIQUINOL BIOSYNTHESIS | 8 | 7.68e-01 | -6.02e-02 | 0.99800 |
| REACTOME SARS COV 2 ACTIVATES MODULATES INNATE AND ADAPTIVE IMMUNE RESPONSES | 118 | 7.68e-01 | -1.57e-02 | 0.99800 |
| REACTOME SUMOYLATION OF IMMUNE RESPONSE PROTEINS | 10 | 7.69e-01 | -5.37e-02 | 0.99800 |
| REACTOME FATTY ACIDS BOUND TO GPR40 FFAR1 REGULATE INSULIN SECRETION | 8 | 7.69e-01 | -5.99e-02 | 0.99800 |
| REACTOME TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT | 18 | 7.70e-01 | -3.98e-02 | 0.99800 |
| REACTOME INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | 28 | 7.71e-01 | 3.18e-02 | 0.99800 |
| REACTOME CALCINEURIN ACTIVATES NFAT | 9 | 7.71e-01 | 5.60e-02 | 0.99800 |
| REACTOME SPRY REGULATION OF FGF SIGNALING | 16 | 7.71e-01 | -4.20e-02 | 0.99800 |
| REACTOME DEGRADATION OF CYSTEINE AND HOMOCYSTEINE | 15 | 7.71e-01 | -4.33e-02 | 0.99800 |
| REACTOME ORC1 REMOVAL FROM CHROMATIN | 70 | 7.73e-01 | -2.00e-02 | 0.99800 |
| REACTOME CRISTAE FORMATION | 27 | 7.73e-01 | -3.21e-02 | 0.99800 |
| REACTOME VIRAL MESSENGER RNA SYNTHESIS | 44 | 7.73e-01 | -2.51e-02 | 0.99800 |
| REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL | 12 | 7.74e-01 | 4.79e-02 | 0.99800 |
| REACTOME RIBAVIRIN ADME | 11 | 7.75e-01 | -4.98e-02 | 0.99800 |
| REACTOME NUCLEOTIDE SALVAGE | 21 | 7.76e-01 | 3.59e-02 | 0.99800 |
| REACTOME P75NTR SIGNALS VIA NF KB | 15 | 7.76e-01 | 4.25e-02 | 0.99800 |
| REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | 19 | 7.76e-01 | -3.76e-02 | 0.99800 |
| REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX IN CANCER | 8 | 7.77e-01 | -5.79e-02 | 0.99800 |
| REACTOME INTEGRATION OF ENERGY METABOLISM | 105 | 7.77e-01 | 1.60e-02 | 0.99800 |
| REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES | 7 | 7.78e-01 | 6.16e-02 | 0.99800 |
| REACTOME SUMOYLATION | 179 | 7.78e-01 | -1.22e-02 | 0.99800 |
| REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS | 101 | 7.79e-01 | -1.62e-02 | 0.99800 |
| REACTOME FORMATION OF APOPTOSOME | 10 | 7.80e-01 | -5.11e-02 | 0.99800 |
| REACTOME METALLOPROTEASE DUBS | 36 | 7.80e-01 | 2.69e-02 | 0.99800 |
| REACTOME PROSTANOID LIGAND RECEPTORS | 9 | 7.81e-01 | -5.36e-02 | 0.99800 |
| REACTOME METABOLISM OF VITAMINS AND COFACTORS | 185 | 7.81e-01 | 1.19e-02 | 0.99800 |
| REACTOME ABACAVIR ADME | 9 | 7.82e-01 | 5.33e-02 | 0.99800 |
| REACTOME OPSINS | 7 | 7.83e-01 | 6.01e-02 | 0.99800 |
| REACTOME FRUCTOSE CATABOLISM | 5 | 7.84e-01 | -7.09e-02 | 0.99800 |
| REACTOME NEPHRIN FAMILY INTERACTIONS | 22 | 7.85e-01 | 3.37e-02 | 0.99800 |
| REACTOME SARS COV 2 MODULATES AUTOPHAGY | 11 | 7.85e-01 | -4.76e-02 | 0.99800 |
| REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | 105 | 7.85e-01 | 1.54e-02 | 0.99800 |
| REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE | 109 | 7.87e-01 | -1.50e-02 | 0.99800 |
| REACTOME TRNA PROCESSING | 105 | 7.87e-01 | 1.53e-02 | 0.99800 |
| REACTOME OXIDATIVE STRESS INDUCED SENESCENCE | 118 | 7.87e-01 | -1.44e-02 | 0.99800 |
| REACTOME CD163 MEDIATING AN ANTI INFLAMMATORY RESPONSE | 9 | 7.88e-01 | -5.17e-02 | 0.99800 |
| REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX | 32 | 7.89e-01 | 2.74e-02 | 0.99800 |
| REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT | 159 | 7.89e-01 | 1.23e-02 | 0.99800 |
| REACTOME LDL REMODELING | 6 | 7.90e-01 | -6.27e-02 | 0.99800 |
| REACTOME POLYMERASE SWITCHING | 13 | 7.90e-01 | -4.26e-02 | 0.99800 |
| REACTOME SARS COV 2 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS | 12 | 7.90e-01 | -4.43e-02 | 0.99800 |
| REACTOME TOLL LIKE RECEPTOR CASCADES | 158 | 7.91e-01 | 1.22e-02 | 0.99800 |
| REACTOME SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER | 54 | 7.92e-01 | 2.08e-02 | 0.99800 |
| REACTOME OVARIAN TUMOR DOMAIN PROTEASES | 36 | 7.93e-01 | -2.53e-02 | 0.99900 |
| REACTOME MAPK6 MAPK4 SIGNALING | 91 | 7.94e-01 | -1.58e-02 | 0.99900 |
| REACTOME RRNA MODIFICATION IN THE MITOCHONDRION | 6 | 7.95e-01 | 6.13e-02 | 0.99900 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS | 12 | 7.95e-01 | -4.33e-02 | 0.99900 |
| REACTOME SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA PHE | 6 | 7.98e-01 | -6.03e-02 | 0.99900 |
| REACTOME IRON UPTAKE AND TRANSPORT | 56 | 7.98e-01 | 1.98e-02 | 0.99900 |
| REACTOME UREA CYCLE | 9 | 7.99e-01 | 4.90e-02 | 0.99900 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST | 18 | 7.99e-01 | 3.46e-02 | 0.99900 |
| REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | 32 | 8.01e-01 | -2.58e-02 | 0.99900 |
| REACTOME THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT | 77 | 8.01e-01 | 1.66e-02 | 0.99900 |
| REACTOME ACTIVATED NTRK3 SIGNALS THROUGH RAS | 8 | 8.02e-01 | -5.13e-02 | 0.99900 |
| REACTOME CREATION OF C4 AND C2 ACTIVATORS | 14 | 8.02e-01 | 3.87e-02 | 0.99900 |
| REACTOME CALCITONIN LIKE LIGAND RECEPTORS | 10 | 8.02e-01 | 4.58e-02 | 0.99900 |
| REACTOME ACYL CHAIN REMODELLING OF PI | 17 | 8.02e-01 | -3.51e-02 | 0.99900 |
| REACTOME REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO | 10 | 8.02e-01 | 4.57e-02 | 0.99900 |
| REACTOME ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS | 87 | 8.03e-01 | 1.55e-02 | 0.99900 |
| REACTOME GP1B IX V ACTIVATION SIGNALLING | 11 | 8.03e-01 | -4.34e-02 | 0.99900 |
| REACTOME NR1H2 AND NR1H3 MEDIATED SIGNALING | 46 | 8.05e-01 | 2.11e-02 | 0.99900 |
| REACTOME TELOMERE C STRAND SYNTHESIS INITIATION | 12 | 8.05e-01 | 4.11e-02 | 0.99900 |
| REACTOME MITOCHONDRIAL BIOGENESIS | 87 | 8.07e-01 | -1.52e-02 | 0.99900 |
| REACTOME ZINC TRANSPORTERS | 15 | 8.07e-01 | -3.64e-02 | 0.99900 |
| REACTOME RRNA PROCESSING IN THE MITOCHONDRION | 9 | 8.10e-01 | 4.64e-02 | 0.99900 |
| REACTOME METABOLISM OF AMINE DERIVED HORMONES | 17 | 8.10e-01 | 3.37e-02 | 0.99900 |
| REACTOME SIGNALING BY ERBB2 | 50 | 8.11e-01 | -1.96e-02 | 0.99900 |
| REACTOME MODULATION BY MTB OF HOST IMMUNE SYSTEM | 6 | 8.11e-01 | -5.63e-02 | 0.99900 |
| REACTOME CELLULAR RESPONSE TO STARVATION | 147 | 8.12e-01 | -1.14e-02 | 0.99900 |
| REACTOME P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1 | 6 | 8.13e-01 | 5.58e-02 | 0.99900 |
| REACTOME MATURATION OF SARS COV 1 SPIKE PROTEIN | 5 | 8.13e-01 | -6.10e-02 | 0.99900 |
| REACTOME PYRUVATE METABOLISM | 29 | 8.14e-01 | -2.53e-02 | 0.99900 |
| REACTOME NECTIN NECL TRANS HETERODIMERIZATION | 7 | 8.15e-01 | -5.12e-02 | 0.99900 |
| REACTOME FBXW7 MUTANTS AND NOTCH1 IN CANCER | 5 | 8.16e-01 | -6.01e-02 | 0.99900 |
| REACTOME FLT3 SIGNALING THROUGH SRC FAMILY KINASES | 6 | 8.16e-01 | 5.49e-02 | 0.99900 |
| REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | 9 | 8.16e-01 | 4.47e-02 | 0.99900 |
| REACTOME REGULATION OF SIGNALING BY CBL | 22 | 8.17e-01 | -2.85e-02 | 0.99900 |
| REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB | 5 | 8.17e-01 | 5.96e-02 | 0.99900 |
| REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM | 23 | 8.18e-01 | 2.78e-02 | 0.99900 |
| REACTOME RNA POLYMERASE III TRANSCRIPTION | 41 | 8.18e-01 | -2.08e-02 | 0.99900 |
| REACTOME REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR | 11 | 8.19e-01 | -3.99e-02 | 0.99900 |
| REACTOME FLT3 SIGNALING | 38 | 8.19e-01 | -2.14e-02 | 0.99900 |
| REACTOME DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE | 17 | 8.20e-01 | 3.20e-02 | 0.99900 |
| REACTOME REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS | 11 | 8.21e-01 | -3.95e-02 | 0.99900 |
| REACTOME GPVI MEDIATED ACTIVATION CASCADE | 35 | 8.22e-01 | -2.20e-02 | 0.99900 |
| REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | 19 | 8.23e-01 | 2.97e-02 | 0.99900 |
| REACTOME REGULATION BY C FLIP | 11 | 8.23e-01 | 3.90e-02 | 0.99900 |
| REACTOME ANDROGEN BIOSYNTHESIS | 11 | 8.24e-01 | -3.88e-02 | 0.99900 |
| REACTOME DISEASES OF IMMUNE SYSTEM | 29 | 8.24e-01 | 2.39e-02 | 0.99900 |
| REACTOME ADHERENS JUNCTIONS INTERACTIONS | 33 | 8.24e-01 | -2.24e-02 | 0.99900 |
| REACTOME CHYLOMICRON CLEARANCE | 5 | 8.25e-01 | 5.70e-02 | 0.99900 |
| REACTOME SIGNALING BY FGFR4 | 40 | 8.27e-01 | -2.00e-02 | 0.99900 |
| REACTOME TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE | 10 | 8.27e-01 | -3.98e-02 | 0.99900 |
| REACTOME WAX AND PLASMALOGEN BIOSYNTHESIS | 5 | 8.28e-01 | -5.61e-02 | 0.99900 |
| REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES | 11 | 8.28e-01 | -3.78e-02 | 0.99900 |
| REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | 48 | 8.28e-01 | -1.81e-02 | 0.99900 |
| REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | 15 | 8.29e-01 | 3.22e-02 | 0.99900 |
| REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING | 29 | 8.29e-01 | -2.32e-02 | 0.99900 |
| REACTOME DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING | 61 | 8.29e-01 | -1.60e-02 | 0.99900 |
| REACTOME FCERI MEDIATED MAPK ACTIVATION | 32 | 8.30e-01 | 2.19e-02 | 0.99900 |
| REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS | 27 | 8.30e-01 | -2.39e-02 | 0.99900 |
| REACTOME KETONE BODY METABOLISM | 9 | 8.33e-01 | -4.06e-02 | 0.99900 |
| REACTOME SIGNALLING TO P38 VIA RIT AND RIN | 5 | 8.34e-01 | -5.41e-02 | 0.99900 |
| REACTOME ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE | 9 | 8.34e-01 | 4.03e-02 | 0.99900 |
| REACTOME CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS | 19 | 8.35e-01 | 2.76e-02 | 0.99900 |
| REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES | 10 | 8.35e-01 | 3.80e-02 | 0.99900 |
| REACTOME MRNA CAPPING | 28 | 8.36e-01 | 2.26e-02 | 0.99900 |
| REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA | 25 | 8.36e-01 | -2.39e-02 | 0.99900 |
| REACTOME SIGNALING BY ALK IN CANCER | 53 | 8.37e-01 | -1.64e-02 | 0.99900 |
| REACTOME MATURATION OF SARS COV 2 SPIKE PROTEIN | 35 | 8.37e-01 | -2.01e-02 | 0.99900 |
| REACTOME SIGNALING BY BMP | 27 | 8.38e-01 | -2.28e-02 | 0.99900 |
| REACTOME RHO GTPASES ACTIVATE CIT | 19 | 8.38e-01 | -2.70e-02 | 0.99900 |
| REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS | 5 | 8.39e-01 | 5.25e-02 | 0.99900 |
| REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | 30 | 8.40e-01 | 2.13e-02 | 0.99900 |
| REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | 12 | 8.41e-01 | 3.35e-02 | 0.99900 |
| REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | 38 | 8.41e-01 | 1.88e-02 | 0.99900 |
| REACTOME FGFRL1 MODULATION OF FGFR1 SIGNALING | 13 | 8.43e-01 | -3.18e-02 | 0.99900 |
| REACTOME COMMON PATHWAY OF FIBRIN CLOT FORMATION | 21 | 8.44e-01 | -2.49e-02 | 0.99900 |
| REACTOME PI3K AKT SIGNALING IN CANCER | 103 | 8.44e-01 | 1.12e-02 | 0.99900 |
| REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING | 32 | 8.44e-01 | -2.01e-02 | 0.99900 |
| REACTOME GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION | 7 | 8.46e-01 | -4.25e-02 | 0.99900 |
| REACTOME LOSS OF FUNCTION OF SMAD2 3 IN CANCER | 7 | 8.46e-01 | -4.24e-02 | 0.99900 |
| REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | 20 | 8.49e-01 | 2.47e-02 | 0.99900 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES | 61 | 8.49e-01 | -1.41e-02 | 0.99900 |
| REACTOME RHOQ GTPASE CYCLE | 57 | 8.49e-01 | -1.46e-02 | 0.99900 |
| REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION | 74 | 8.49e-01 | -1.28e-02 | 0.99900 |
| REACTOME LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX | 5 | 8.49e-01 | -4.90e-02 | 0.99900 |
| REACTOME RSK ACTIVATION | 5 | 8.50e-01 | 4.90e-02 | 0.99900 |
| REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS | 83 | 8.50e-01 | 1.20e-02 | 0.99900 |
| REACTOME CDC42 GTPASE CYCLE | 144 | 8.50e-01 | -9.11e-03 | 0.99900 |
| REACTOME VOLTAGE GATED POTASSIUM CHANNELS | 42 | 8.51e-01 | -1.68e-02 | 0.99900 |
| REACTOME TRIF MEDIATED PROGRAMMED CELL DEATH | 9 | 8.51e-01 | 3.63e-02 | 0.99900 |
| REACTOME ABC TRANSPORTER DISORDERS | 76 | 8.51e-01 | 1.24e-02 | 0.99900 |
| REACTOME PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS | 21 | 8.52e-01 | -2.35e-02 | 0.99900 |
| REACTOME FRS MEDIATED FGFR4 SIGNALING | 21 | 8.53e-01 | -2.34e-02 | 0.99900 |
| REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | 15 | 8.53e-01 | 2.76e-02 | 0.99900 |
| REACTOME NEUROTRANSMITTER CLEARANCE | 9 | 8.53e-01 | -3.57e-02 | 0.99900 |
| REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | 19 | 8.53e-01 | 2.46e-02 | 0.99900 |
| REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE | 52 | 8.53e-01 | -1.48e-02 | 0.99900 |
| REACTOME SIGNALING BY EGFR IN CANCER | 25 | 8.55e-01 | -2.12e-02 | 0.99900 |
| REACTOME G2 M CHECKPOINTS | 162 | 8.55e-01 | -8.32e-03 | 0.99900 |
| REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION | 45 | 8.55e-01 | -1.57e-02 | 0.99900 |
| REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | 11 | 8.58e-01 | -3.11e-02 | 0.99900 |
| REACTOME HIV TRANSCRIPTION ELONGATION | 42 | 8.59e-01 | -1.58e-02 | 0.99900 |
| REACTOME POLB DEPENDENT LONG PATCH BASE EXCISION REPAIR | 8 | 8.59e-01 | 3.62e-02 | 0.99900 |
| REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE | 37 | 8.60e-01 | -1.67e-02 | 0.99900 |
| REACTOME ATTACHMENT AND ENTRY | 16 | 8.61e-01 | 2.53e-02 | 0.99900 |
| REACTOME DNA DAMAGE REVERSAL | 8 | 8.62e-01 | 3.55e-02 | 0.99900 |
| REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS | 418 | 8.62e-01 | 4.95e-03 | 0.99900 |
| REACTOME G2 M DNA DAMAGE CHECKPOINT | 90 | 8.62e-01 | 1.06e-02 | 0.99900 |
| REACTOME SYNTHESIS OF KETONE BODIES | 8 | 8.63e-01 | 3.52e-02 | 0.99900 |
| REACTOME NOSTRIN MEDIATED ENOS TRAFFICKING | 5 | 8.63e-01 | 4.46e-02 | 0.99900 |
| REACTOME DNA STRAND ELONGATION | 31 | 8.63e-01 | -1.78e-02 | 0.99900 |
| REACTOME DOWNREGULATION OF ERBB2 SIGNALING | 29 | 8.64e-01 | 1.84e-02 | 0.99900 |
| REACTOME HIV ELONGATION ARREST AND RECOVERY | 33 | 8.65e-01 | -1.72e-02 | 0.99900 |
| REACTOME COMPLEMENT CASCADE | 54 | 8.65e-01 | -1.34e-02 | 0.99900 |
| REACTOME SIGNALING BY FGFR3 | 39 | 8.66e-01 | -1.56e-02 | 0.99900 |
| REACTOME N GLYCAN ANTENNAE ELONGATION | 15 | 8.66e-01 | -2.51e-02 | 0.99900 |
| REACTOME REGULATION OF PTEN LOCALIZATION | 8 | 8.67e-01 | 3.42e-02 | 0.99900 |
| REACTOME DECTIN 2 FAMILY | 26 | 8.68e-01 | 1.88e-02 | 0.99900 |
| REACTOME KERATAN SULFATE DEGRADATION | 13 | 8.68e-01 | 2.66e-02 | 0.99900 |
| REACTOME METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS | 122 | 8.70e-01 | -8.61e-03 | 0.99900 |
| REACTOME RNA POLYMERASE II TRANSCRIBES SNRNA GENES | 77 | 8.70e-01 | 1.08e-02 | 0.99900 |
| REACTOME VEGFR2 MEDIATED CELL PROLIFERATION | 19 | 8.70e-01 | -2.17e-02 | 0.99900 |
| REACTOME GLUCOCORTICOID BIOSYNTHESIS | 10 | 8.70e-01 | -2.98e-02 | 0.99900 |
| REACTOME EGFR INTERACTS WITH PHOSPHOLIPASE C GAMMA | 9 | 8.70e-01 | 3.14e-02 | 0.99900 |
| REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER | 77 | 8.72e-01 | 1.07e-02 | 0.99900 |
| REACTOME LRR FLII INTERACTING PROTEIN 1 LRRFIP1 ACTIVATES TYPE I IFN PRODUCTION | 5 | 8.72e-01 | 4.15e-02 | 0.99900 |
| REACTOME ACTIVATION OF CASPASES THROUGH APOPTOSOME MEDIATED CLEAVAGE | 5 | 8.74e-01 | -4.09e-02 | 0.99900 |
| REACTOME HDL REMODELING | 10 | 8.74e-01 | -2.88e-02 | 0.99900 |
| REACTOME SHC RELATED EVENTS TRIGGERED BY IGF1R | 9 | 8.75e-01 | 3.03e-02 | 0.99900 |
| REACTOME SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION | 8 | 8.78e-01 | -3.14e-02 | 0.99900 |
| REACTOME AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY | 8 | 8.78e-01 | 3.13e-02 | 0.99900 |
| REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | 10 | 8.78e-01 | -2.79e-02 | 0.99900 |
| REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR4 | 26 | 8.79e-01 | 1.72e-02 | 0.99900 |
| REACTOME EPHB MEDIATED FORWARD SIGNALING | 41 | 8.79e-01 | -1.37e-02 | 0.99900 |
| REACTOME FORMATION OF PARAXIAL MESODERM | 22 | 8.79e-01 | 1.87e-02 | 0.99900 |
| REACTOME FASL CD95L SIGNALING | 5 | 8.81e-01 | 3.88e-02 | 0.99900 |
| REACTOME COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING | 38 | 8.81e-01 | -1.41e-02 | 0.99900 |
| REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM | 50 | 8.81e-01 | -1.23e-02 | 0.99900 |
| REACTOME PENTOSE PHOSPHATE PATHWAY | 12 | 8.82e-01 | 2.48e-02 | 0.99900 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE | 20 | 8.82e-01 | -1.92e-02 | 0.99900 |
| REACTOME METHYLATION | 14 | 8.82e-01 | -2.29e-02 | 0.99900 |
| REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES | 34 | 8.82e-01 | -1.47e-02 | 0.99900 |
| REACTOME AUTOPHAGY | 144 | 8.83e-01 | -7.12e-03 | 0.99900 |
| REACTOME FORMATION OF THE CORNIFIED ENVELOPE | 125 | 8.83e-01 | -7.63e-03 | 0.99900 |
| REACTOME SIGNALING BY MRAS COMPLEX MUTANTS | 7 | 8.85e-01 | -3.15e-02 | 0.99900 |
| REACTOME MOLYBDENUM COFACTOR BIOSYNTHESIS | 6 | 8.85e-01 | 3.40e-02 | 0.99900 |
| REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER | 49 | 8.86e-01 | -1.18e-02 | 0.99900 |
| REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | 11 | 8.87e-01 | -2.48e-02 | 0.99900 |
| REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS | 63 | 8.87e-01 | -1.03e-02 | 0.99900 |
| REACTOME PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS | 8 | 8.88e-01 | -2.89e-02 | 0.99900 |
| REACTOME SULFUR AMINO ACID METABOLISM | 27 | 8.88e-01 | -1.57e-02 | 0.99900 |
| REACTOME AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA | 54 | 8.89e-01 | -1.10e-02 | 0.99900 |
| REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | 76 | 8.90e-01 | -9.15e-03 | 0.99900 |
| REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG | 7 | 8.91e-01 | 2.99e-02 | 0.99900 |
| REACTOME TOLL LIKE RECEPTOR 9 TLR9 CASCADE | 100 | 8.91e-01 | -7.90e-03 | 0.99900 |
| REACTOME PI5P REGULATES TP53 ACETYLATION | 9 | 8.92e-01 | 2.62e-02 | 0.99900 |
| REACTOME SIGNALING BY ERBB2 IN CANCER | 26 | 8.92e-01 | -1.54e-02 | 0.99900 |
| REACTOME BICARBONATE TRANSPORTERS | 10 | 8.93e-01 | -2.46e-02 | 0.99900 |
| REACTOME PLASMA LIPOPROTEIN ASSEMBLY | 19 | 8.93e-01 | -1.78e-02 | 0.99900 |
| REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR | 24 | 8.93e-01 | -1.58e-02 | 0.99900 |
| REACTOME NRCAM INTERACTIONS | 6 | 8.94e-01 | -3.14e-02 | 0.99900 |
| REACTOME SHC1 EVENTS IN ERBB2 SIGNALING | 22 | 8.94e-01 | -1.64e-02 | 0.99900 |
| REACTOME ROLE OF ABL IN ROBO SLIT SIGNALING | 8 | 8.95e-01 | 2.69e-02 | 0.99900 |
| REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON | 17 | 8.96e-01 | -1.83e-02 | 0.99900 |
| REACTOME HDL CLEARANCE | 5 | 8.96e-01 | -3.37e-02 | 0.99900 |
| REACTOME CYP2E1 REACTIONS | 10 | 8.97e-01 | 2.37e-02 | 0.99900 |
| REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION | 89 | 8.97e-01 | -7.93e-03 | 0.99900 |
| REACTOME SIGNALING BY NODAL | 20 | 8.99e-01 | -1.64e-02 | 0.99900 |
| REACTOME AGGREPHAGY | 42 | 9.00e-01 | 1.12e-02 | 0.99900 |
| REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | 15 | 9.01e-01 | -1.86e-02 | 0.99900 |
| REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS | 60 | 9.01e-01 | 9.31e-03 | 0.99900 |
| REACTOME DEFECTIVE CHST6 CAUSES MCDC1 | 8 | 9.01e-01 | -2.53e-02 | 0.99900 |
| REACTOME BASIGIN INTERACTIONS | 24 | 9.03e-01 | -1.44e-02 | 0.99900 |
| REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX | 39 | 9.03e-01 | 1.12e-02 | 0.99900 |
| REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL | 15 | 9.03e-01 | -1.81e-02 | 0.99900 |
| REACTOME ACYL CHAIN REMODELLING OF PS | 22 | 9.04e-01 | 1.49e-02 | 0.99900 |
| REACTOME CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA | 63 | 9.04e-01 | -8.79e-03 | 0.99900 |
| REACTOME SHC MEDIATED CASCADE FGFR4 | 19 | 9.06e-01 | -1.57e-02 | 0.99900 |
| REACTOME METALLOTHIONEINS BIND METALS | 11 | 9.06e-01 | 2.06e-02 | 0.99900 |
| REACTOME PHASE 3 RAPID REPOLARISATION | 8 | 9.08e-01 | -2.37e-02 | 0.99900 |
| REACTOME SUMOYLATION OF DNA METHYLATION PROTEINS | 16 | 9.08e-01 | -1.68e-02 | 0.99900 |
| REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | 18 | 9.08e-01 | 1.57e-02 | 0.99900 |
| REACTOME PURINE SALVAGE | 12 | 9.11e-01 | 1.87e-02 | 0.99900 |
| REACTOME MAP2K AND MAPK ACTIVATION | 38 | 9.11e-01 | 1.05e-02 | 0.99900 |
| REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING | 30 | 9.12e-01 | 1.16e-02 | 0.99900 |
| REACTOME CYTOCHROME C MEDIATED APOPTOTIC RESPONSE | 12 | 9.13e-01 | 1.83e-02 | 0.99900 |
| REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND | 21 | 9.13e-01 | 1.38e-02 | 0.99900 |
| REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE | 8 | 9.13e-01 | 2.23e-02 | 0.99900 |
| REACTOME SIGNALING BY FGFR2 IIIA TM | 19 | 9.13e-01 | 1.44e-02 | 0.99900 |
| REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | 22 | 9.14e-01 | 1.32e-02 | 0.99900 |
| REACTOME L1CAM INTERACTIONS | 112 | 9.15e-01 | 5.84e-03 | 0.99900 |
| REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM | 45 | 9.15e-01 | 9.18e-03 | 0.99900 |
| REACTOME HDR THROUGH MMEJ ALT NHEJ | 12 | 9.15e-01 | -1.77e-02 | 0.99900 |
| REACTOME TRNA MODIFICATION IN THE MITOCHONDRION | 8 | 9.16e-01 | 2.14e-02 | 0.99900 |
| REACTOME SIGNALING BY CSF3 G CSF | 30 | 9.16e-01 | -1.11e-02 | 0.99900 |
| REACTOME REGULATION OF PTEN STABILITY AND ACTIVITY | 67 | 9.17e-01 | 7.38e-03 | 0.99900 |
| REACTOME METABOLISM OF POLYAMINES | 56 | 9.17e-01 | 8.06e-03 | 0.99900 |
| REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | 16 | 9.18e-01 | 1.48e-02 | 0.99900 |
| REACTOME TRANSCRIPTION OF THE HIV GENOME | 66 | 9.19e-01 | -7.25e-03 | 0.99900 |
| REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS | 20 | 9.19e-01 | -1.32e-02 | 0.99900 |
| REACTOME PROTON COUPLED MONOCARBOXYLATE TRANSPORT | 6 | 9.20e-01 | -2.37e-02 | 0.99900 |
| REACTOME SIGNALING BY EGFR | 49 | 9.21e-01 | 8.20e-03 | 0.99900 |
| REACTOME NICOTINAMIDE SALVAGING | 19 | 9.21e-01 | 1.31e-02 | 0.99900 |
| REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES | 34 | 9.22e-01 | -9.67e-03 | 0.99900 |
| REACTOME DEFECTIVE RIPK1 MEDIATED REGULATED NECROSIS | 7 | 9.23e-01 | 2.12e-02 | 0.99900 |
| REACTOME SHC1 EVENTS IN EGFR SIGNALING | 14 | 9.23e-01 | -1.50e-02 | 0.99900 |
| REACTOME NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 24 | 9.24e-01 | -1.13e-02 | 0.99900 |
| REACTOME KSRP KHSRP BINDS AND DESTABILIZES MRNA | 17 | 9.24e-01 | 1.34e-02 | 0.99900 |
| REACTOME LIPID PARTICLE ORGANIZATION | 6 | 9.24e-01 | 2.24e-02 | 0.99900 |
| REACTOME METABOLISM OF COFACTORS | 19 | 9.25e-01 | -1.25e-02 | 0.99900 |
| REACTOME MIRO GTPASE CYCLE | 8 | 9.26e-01 | -1.90e-02 | 0.99900 |
| REACTOME REGULATION OF NPAS4 GENE EXPRESSION | 13 | 9.27e-01 | 1.47e-02 | 0.99900 |
| REACTOME ACTIVATION OF RAS IN B CELLS | 5 | 9.28e-01 | -2.35e-02 | 0.99900 |
| REACTOME PHASE 2 PLATEAU PHASE | 14 | 9.28e-01 | 1.39e-02 | 0.99900 |
| REACTOME FGFR1 LIGAND BINDING AND ACTIVATION | 15 | 9.28e-01 | 1.34e-02 | 0.99900 |
| REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR4 | 14 | 9.28e-01 | 1.39e-02 | 0.99900 |
| REACTOME THYROXINE BIOSYNTHESIS | 10 | 9.29e-01 | 1.63e-02 | 0.99900 |
| REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | 14 | 9.29e-01 | 1.37e-02 | 0.99900 |
| REACTOME BETA CATENIN INDEPENDENT WNT SIGNALING | 145 | 9.30e-01 | 4.25e-03 | 0.99900 |
| REACTOME CALNEXIN CALRETICULIN CYCLE | 26 | 9.30e-01 | -1.00e-02 | 0.99900 |
| REACTOME SIGNALING BY ERBB4 | 57 | 9.31e-01 | 6.62e-03 | 0.99900 |
| REACTOME HSF1 DEPENDENT TRANSACTIVATION | 37 | 9.32e-01 | -8.11e-03 | 0.99900 |
| REACTOME INTEGRIN CELL SURFACE INTERACTIONS | 83 | 9.34e-01 | -5.27e-03 | 0.99900 |
| REACTOME FREE FATTY ACIDS REGULATE INSULIN SECRETION | 10 | 9.34e-01 | -1.51e-02 | 0.99900 |
| REACTOME EPITHELIAL MESENCHYMAL TRANSITION EMT DURING GASTRULATION | 7 | 9.36e-01 | 1.76e-02 | 0.99900 |
| REACTOME SIGNALING BY FGFR4 IN DISEASE | 11 | 9.36e-01 | -1.40e-02 | 0.99900 |
| REACTOME PI 3K CASCADE FGFR3 | 17 | 9.36e-01 | 1.13e-02 | 0.99900 |
| REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | 353 | 9.36e-01 | -2.48e-03 | 0.99900 |
| REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY | 46 | 9.37e-01 | -6.75e-03 | 0.99900 |
| REACTOME FCERI MEDIATED NF KB ACTIVATION | 78 | 9.37e-01 | -5.16e-03 | 0.99900 |
| REACTOME PURINE CATABOLISM | 17 | 9.39e-01 | 1.07e-02 | 0.99900 |
| REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF | 17 | 9.39e-01 | 1.06e-02 | 0.99900 |
| REACTOME ESTROGEN BIOSYNTHESIS | 6 | 9.39e-01 | 1.79e-02 | 0.99900 |
| REACTOME NONSENSE MEDIATED DECAY NMD | 107 | 9.40e-01 | -4.24e-03 | 0.99900 |
| REACTOME ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM | 12 | 9.40e-01 | -1.26e-02 | 0.99900 |
| REACTOME PCP CE PATHWAY | 91 | 9.41e-01 | -4.47e-03 | 0.99900 |
| REACTOME MASTL FACILITATES MITOTIC PROGRESSION | 10 | 9.42e-01 | 1.33e-02 | 0.99900 |
| REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K | 12 | 9.42e-01 | -1.20e-02 | 0.99900 |
| REACTOME RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION | 22 | 9.42e-01 | 8.89e-03 | 0.99900 |
| REACTOME CITRIC ACID CYCLE TCA CYCLE | 21 | 9.44e-01 | -8.92e-03 | 0.99900 |
| REACTOME DNA REPLICATION PRE INITIATION | 150 | 9.44e-01 | 3.35e-03 | 0.99900 |
| REACTOME N GLYCAN TRIMMING AND ELONGATION IN THE CIS GOLGI | 5 | 9.44e-01 | 1.80e-02 | 0.99900 |
| REACTOME TYSND1 CLEAVES PEROXISOMAL PROTEINS | 7 | 9.45e-01 | -1.50e-02 | 0.99900 |
| REACTOME REGULATION OF GENE EXPRESSION IN ENDOCRINE COMMITTED NEUROG3 PROGENITOR CELLS | 5 | 9.46e-01 | 1.74e-02 | 0.99900 |
| REACTOME TRANSLESION SYNTHESIS BY POLH | 19 | 9.46e-01 | -8.90e-03 | 0.99900 |
| REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY DVL INTERACTING PROTEINS | 5 | 9.47e-01 | 1.72e-02 | 0.99900 |
| REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | 22 | 9.48e-01 | 8.08e-03 | 0.99900 |
| REACTOME ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING | 23 | 9.48e-01 | 7.85e-03 | 0.99900 |
| REACTOME NEUROFASCIN INTERACTIONS | 6 | 9.48e-01 | 1.53e-02 | 0.99900 |
| REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION | 29 | 9.50e-01 | -6.78e-03 | 0.99900 |
| REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY | 26 | 9.50e-01 | 7.12e-03 | 0.99900 |
| REACTOME NEF AND SIGNAL TRANSDUCTION | 8 | 9.50e-01 | 1.28e-02 | 0.99900 |
| REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS | 19 | 9.51e-01 | -8.22e-03 | 0.99900 |
| REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES | 16 | 9.51e-01 | -8.84e-03 | 0.99900 |
| REACTOME SYNTHESIS OF DOLICHYL PHOSPHATE | 6 | 9.52e-01 | 1.43e-02 | 0.99900 |
| REACTOME TRANSCRIPTIONAL REGULATION BY RUNX3 | 94 | 9.52e-01 | -3.59e-03 | 0.99900 |
| REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | 99 | 9.52e-01 | -3.49e-03 | 0.99900 |
| REACTOME SENSORY PERCEPTION OF TASTE | 47 | 9.52e-01 | 5.04e-03 | 0.99900 |
| REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS | 66 | 9.53e-01 | -4.24e-03 | 0.99900 |
| REACTOME BIOSYNTHESIS OF MARESINS | 8 | 9.53e-01 | -1.19e-02 | 0.99900 |
| REACTOME FRS MEDIATED FGFR1 SIGNALING | 23 | 9.54e-01 | -6.98e-03 | 0.99900 |
| REACTOME REACTIONS SPECIFIC TO THE COMPLEX N GLYCAN SYNTHESIS PATHWAY | 10 | 9.54e-01 | 1.05e-02 | 0.99900 |
| REACTOME INTERLEUKIN 2 SIGNALING | 11 | 9.56e-01 | 9.60e-03 | 0.99900 |
| REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES | 29 | 9.58e-01 | 5.60e-03 | 0.99900 |
| REACTOME FC EPSILON RECEPTOR FCERI SIGNALING | 127 | 9.59e-01 | 2.67e-03 | 0.99900 |
| REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III | 31 | 9.59e-01 | 5.38e-03 | 0.99900 |
| REACTOME PARACETAMOL ADME | 26 | 9.59e-01 | 5.82e-03 | 0.99900 |
| REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS | 46 | 9.59e-01 | -4.37e-03 | 0.99900 |
| REACTOME DEX H BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION | 7 | 9.60e-01 | 1.11e-02 | 0.99900 |
| REACTOME BETA OXIDATION OF BUTANOYL COA TO ACETYL COA | 5 | 9.60e-01 | -1.31e-02 | 0.99900 |
| REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR3 | 24 | 9.60e-01 | -5.84e-03 | 0.99900 |
| REACTOME ACYL CHAIN REMODELLING OF PG | 18 | 9.61e-01 | -6.68e-03 | 0.99900 |
| REACTOME CHYLOMICRON REMODELING | 10 | 9.61e-01 | -8.85e-03 | 0.99900 |
| REACTOME SIALIC ACID METABOLISM | 33 | 9.62e-01 | -4.85e-03 | 0.99900 |
| REACTOME TRANSCRIPTIONAL REGULATION BY RUNX2 | 117 | 9.62e-01 | 2.53e-03 | 0.99900 |
| REACTOME CREATINE METABOLISM | 9 | 9.62e-01 | -9.07e-03 | 0.99900 |
| REACTOME GPER1 SIGNALING | 45 | 9.63e-01 | -4.01e-03 | 0.99900 |
| REACTOME CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND | 16 | 9.63e-01 | 6.72e-03 | 0.99900 |
| REACTOME NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION | 20 | 9.63e-01 | -5.93e-03 | 0.99900 |
| REACTOME GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION | 14 | 9.64e-01 | 7.03e-03 | 0.99900 |
| REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | 28 | 9.64e-01 | 4.89e-03 | 0.99900 |
| REACTOME NEUROTOXICITY OF CLOSTRIDIUM TOXINS | 10 | 9.66e-01 | -7.77e-03 | 0.99900 |
| REACTOME DNA REPLICATION | 178 | 9.68e-01 | 1.77e-03 | 0.99900 |
| REACTOME CHYLOMICRON ASSEMBLY | 10 | 9.68e-01 | 7.33e-03 | 0.99900 |
| REACTOME ACTIVATED NTRK3 SIGNALS THROUGH PI3K | 6 | 9.68e-01 | 9.41e-03 | 0.99900 |
| REACTOME DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS | 14 | 9.69e-01 | -5.97e-03 | 0.99900 |
| REACTOME HIV TRANSCRIPTION INITIATION | 43 | 9.70e-01 | 3.37e-03 | 0.99900 |
| REACTOME TRAF6 MEDIATED NF KB ACTIVATION | 24 | 9.71e-01 | 4.34e-03 | 0.99900 |
| REACTOME ACYL CHAIN REMODELLING OF PC | 27 | 9.72e-01 | -3.96e-03 | 0.99900 |
| REACTOME FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS | 8 | 9.72e-01 | -7.06e-03 | 0.99900 |
| REACTOME SIGNALING BY NTRK3 TRKC | 17 | 9.73e-01 | -4.75e-03 | 0.99900 |
| REACTOME MYD88 INDEPENDENT TLR4 CASCADE | 103 | 9.74e-01 | -1.87e-03 | 0.99900 |
| REACTOME CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER | 25 | 9.75e-01 | 3.66e-03 | 0.99900 |
| REACTOME HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS | 9 | 9.75e-01 | -5.97e-03 | 0.99900 |
| REACTOME CARNITINE METABOLISM | 13 | 9.75e-01 | -4.92e-03 | 0.99900 |
| REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION | 42 | 9.76e-01 | 2.73e-03 | 0.99900 |
| REACTOME FGFR3 LIGAND BINDING AND ACTIVATION | 12 | 9.76e-01 | 5.08e-03 | 0.99900 |
| REACTOME CLEC7A DECTIN 1 SIGNALING | 97 | 9.76e-01 | -1.76e-03 | 0.99900 |
| REACTOME SULFIDE OXIDATION TO SULFATE | 6 | 9.77e-01 | 6.85e-03 | 0.99900 |
| REACTOME VITAMIN B1 THIAMIN METABOLISM | 5 | 9.77e-01 | 7.42e-03 | 0.99900 |
| REACTOME G PROTEIN ACTIVATION | 24 | 9.77e-01 | -3.35e-03 | 0.99900 |
| REACTOME INTERLEUKIN 23 SIGNALING | 9 | 9.78e-01 | 5.30e-03 | 0.99900 |
| REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS | 14 | 9.79e-01 | -4.15e-03 | 0.99900 |
| REACTOME TNF SIGNALING | 54 | 9.79e-01 | -2.10e-03 | 0.99900 |
| REACTOME LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME | 11 | 9.79e-01 | 4.55e-03 | 0.99900 |
| REACTOME G PROTEIN BETA GAMMA SIGNALLING | 30 | 9.80e-01 | 2.68e-03 | 0.99900 |
| REACTOME THE ACTIVATION OF ARYLSULFATASES | 8 | 9.80e-01 | 5.06e-03 | 0.99900 |
| REACTOME INTERLEUKIN 1 FAMILY SIGNALING | 146 | 9.81e-01 | -1.14e-03 | 0.99900 |
| REACTOME AZATHIOPRINE ADME | 22 | 9.81e-01 | 2.94e-03 | 0.99900 |
| REACTOME GRB2 EVENTS IN ERBB2 SIGNALING | 16 | 9.82e-01 | -3.20e-03 | 0.99900 |
| REACTOME DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B | 7 | 9.82e-01 | 4.79e-03 | 0.99900 |
| REACTOME FGFR1C LIGAND BINDING AND ACTIVATION | 11 | 9.83e-01 | -3.74e-03 | 0.99900 |
| REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | 11 | 9.83e-01 | -3.72e-03 | 0.99900 |
| REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | 21 | 9.83e-01 | 2.61e-03 | 0.99900 |
| REACTOME CA DEPENDENT EVENTS | 36 | 9.85e-01 | -1.85e-03 | 0.99900 |
| REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | 26 | 9.85e-01 | 2.15e-03 | 0.99900 |
| REACTOME ALPHA DEFENSINS | 6 | 9.85e-01 | -4.41e-03 | 0.99900 |
| REACTOME RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION | 6 | 9.85e-01 | -4.38e-03 | 0.99900 |
| REACTOME MET RECEPTOR ACTIVATION | 6 | 9.86e-01 | -4.00e-03 | 0.99900 |
| REACTOME OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS | 8 | 9.87e-01 | -3.35e-03 | 0.99900 |
| REACTOME PEXOPHAGY | 11 | 9.87e-01 | -2.84e-03 | 0.99900 |
| REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI | 26 | 9.87e-01 | 1.81e-03 | 0.99900 |
| REACTOME ERK MAPK TARGETS | 20 | 9.89e-01 | 1.86e-03 | 0.99900 |
| REACTOME SHC MEDIATED CASCADE FGFR1 | 21 | 9.90e-01 | 1.53e-03 | 1.00000 |
| REACTOME GLYCOSAMINOGLYCAN METABOLISM | 118 | 9.92e-01 | -5.64e-04 | 1.00000 |
| REACTOME TAK1 DEPENDENT IKK AND NF KAPPA B ACTIVATION | 41 | 9.92e-01 | 9.17e-04 | 1.00000 |
| REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | 29 | 9.92e-01 | -1.05e-03 | 1.00000 |
| REACTOME REGULATION OF MECP2 EXPRESSION AND ACTIVITY | 30 | 9.93e-01 | 9.77e-04 | 1.00000 |
| REACTOME DAG AND IP3 SIGNALING | 40 | 9.94e-01 | -7.10e-04 | 1.00000 |
| REACTOME NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 11 | 9.94e-01 | 1.26e-03 | 1.00000 |
| REACTOME INACTIVATION OF CSF3 G CSF SIGNALING | 25 | 9.94e-01 | -8.08e-04 | 1.00000 |
| REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1 | 229 | 9.95e-01 | -2.63e-04 | 1.00000 |
| REACTOME SIGNALING BY FGFR1 | 49 | 9.95e-01 | 5.32e-04 | 1.00000 |
| REACTOME MAPK3 ERK1 ACTIVATION | 10 | 9.97e-01 | -7.18e-04 | 1.00000 |
| REACTOME NUCLEAR PORE COMPLEX NPC DISASSEMBLY | 36 | 9.97e-01 | -3.46e-04 | 1.00000 |
| REACTOME LGI ADAM INTERACTIONS | 14 | 9.97e-01 | 4.87e-04 | 1.00000 |
| REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12 | 22 | 9.99e-01 | -2.11e-04 | 1.00000 |
| REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS | 6 | 9.99e-01 | 3.18e-04 | 1.00000 |
| REACTOME PYRIMIDINE SALVAGE | 10 | 1.00e+00 | -8.18e-05 | 1.00000 |
| REACTOME SMAC XIAP REGULATED APOPTOTIC RESPONSE | 7 | 1.00e+00 | -9.09e-05 | 1.00000 |
| REACTOME TRIGLYCERIDE BIOSYNTHESIS | 12 | 1.00e+00 | -3.03e-05 | 1.00000 |
Detailed Gene set reports
REACTOME_SIGNALING_BY_GPCR
| 593 | |
|---|---|
| set | REACTOME_SIGNALING_BY_GPCR |
| setSize | 673 |
| pANOVA | 1.18e-06 |
| s.dist | 0.11 |
| p.adjustANOVA | 0.00108 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| LPAR5 | 10090 |
| CCL22 | 10065 |
| DRD5 | 10061 |
| SAA1 | 10054 |
| GNGT2 | 10053 |
| GNAT2 | 10030 |
| CCL4 | 10026 |
| CCL5 | 10003 |
| CXCR6 | 9994 |
| TAAR8 | 9991 |
| CXCL1 | 9982 |
| GHRH | 9950 |
| CCR2 | 9938 |
| CCR6 | 9905 |
| TAS2R8 | 9890 |
| CXCR5 | 9845 |
| TAAR1 | 9837 |
| SSTR4 | 9810 |
| CCL13 | 9779 |
| HCAR1 | 9717 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| LPAR5 | 10090 |
| CCL22 | 10065 |
| DRD5 | 10061 |
| SAA1 | 10054 |
| GNGT2 | 10053 |
| GNAT2 | 10030 |
| CCL4 | 10026 |
| CCL5 | 10003 |
| CXCR6 | 9994 |
| TAAR8 | 9991 |
| CXCL1 | 9982 |
| GHRH | 9950 |
| CCR2 | 9938 |
| CCR6 | 9905 |
| TAS2R8 | 9890 |
| CXCR5 | 9845 |
| TAAR1 | 9837 |
| SSTR4 | 9810 |
| CCL13 | 9779 |
| HCAR1 | 9717 |
| RGS11 | 9687 |
| CCL1 | 9680 |
| TAS2R9 | 9605 |
| ARHGEF33 | 9574 |
| TRHR | 9561 |
| CCRL2 | 9506 |
| C3AR1 | 9470 |
| FZD8 | 9445 |
| FPR3 | 9433 |
| TAS2R5 | 9406 |
| RGS21 | 9393 |
| PPBP | 9375 |
| ADGRE3 | 9363 |
| SSTR1 | 9359 |
| GNAI2 | 9357 |
| ACKR3 | 9342 |
| PPP1CA | 9335 |
| CCL16 | 9292 |
| ADCYAP1R1 | 9287 |
| SCT | 9247 |
| HRH3 | 9245 |
| PTGDR2 | 9100 |
| GPR18 | 9057 |
| RAMP2 | 9056 |
| CCL20 | 9053 |
| GPR183 | 9033 |
| ADRA2C | 9020 |
| ADRA1B | 9009 |
| LTB4R | 8989 |
| WNT10A | 8898 |
| CXCR1 | 8889 |
| CHRM4 | 8860 |
| NTSR1 | 8849 |
| C3 | 8800 |
| EDN2 | 8784 |
| ADORA2A | 8757 |
| CCL7 | 8746 |
| ADRA1A | 8688 |
| MC3R | 8676 |
| P2RY1 | 8671 |
| PLPPR3 | 8655 |
| FFAR2 | 8598 |
| CCL23 | 8588 |
| HTR1B | 8578 |
| FZD10 | 8520 |
| GPR83 | 8504 |
| GRM1 | 8496 |
| ADGRE5 | 8456 |
| BDKRB1 | 8451 |
| CNR1 | 8445 |
| LTB4R2 | 8441 |
| GAST | 8422 |
| FZD6 | 8371 |
| CALCRL | 8299 |
| GPR31 | 8287 |
| CCL21 | 8262 |
| PRLH | 8256 |
| CGA | 8227 |
| NPY2R | 8212 |
| GNAZ | 8159 |
| MLNR | 8089 |
| SST | 8074 |
| TACR3 | 8070 |
| LHCGR | 8052 |
| DRD2 | 8046 |
| FZD1 | 8043 |
| GALR1 | 8027 |
| WNT3 | 8005 |
| CRH | 7998 |
| CCK | 7953 |
| CCR1 | 7916 |
| HTR1E | 7901 |
| PDE3B | 7849 |
| UCN2 | 7840 |
| PF4 | 7738 |
| GPR150 | 7698 |
| RXFP1 | 7693 |
| LPAR1 | 7692 |
| MMP3 | 7659 |
| AVPR1B | 7655 |
| PLPPR4 | 7652 |
| TAS2R50 | 7568 |
| F2R | 7565 |
| AKT1 | 7547 |
| NPFFR2 | 7469 |
| ADRA2A | 7409 |
| CXCL13 | 7397 |
| OPRM1 | 7376 |
| HRH2 | 7342 |
| WNT4 | 7338 |
| ARHGEF37 | 7278 |
| NPY1R | 7272 |
| ACKR1 | 7270 |
| HRAS | 7211 |
| UTS2 | 7196 |
| WNT8A | 7194 |
| PDE8B | 7140 |
| GRM2 | 7138 |
| WNT5A | 7123 |
| NPY | 7117 |
| CD55 | 7097 |
| NPS | 7072 |
| GNA15 | 7063 |
| POMC | 7031 |
| PROKR1 | 7028 |
| DAGLA | 7016 |
| OPRK1 | 7013 |
| PPP2R1B | 6984 |
| RGSL1 | 6974 |
| PRKCH | 6955 |
| P2RY2 | 6949 |
| WNT3A | 6948 |
| RGS13 | 6923 |
| PENK | 6920 |
| PPP1R1B | 6847 |
| CCR10 | 6837 |
| CDC42 | 6814 |
| ADM | 6796 |
| NMBR | 6781 |
| MAPK3 | 6757 |
| MGLL | 6734 |
| PREX1 | 6719 |
| CXCL12 | 6660 |
| TAAR2 | 6657 |
| RXFP2 | 6654 |
| DHH | 6641 |
| TRPC6 | 6613 |
| GNB1 | 6594 |
| RGS1 | 6587 |
| PTH | 6578 |
| GPR45 | 6545 |
| CCR4 | 6538 |
| ARHGEF25 | 6532 |
| CAMK2A | 6475 |
| ADCY5 | 6465 |
| GRK6 | 6444 |
| KISS1R | 6441 |
| PLA2G4A | 6436 |
| RGS8 | 6416 |
| PTH1R | 6290 |
| P2RY14 | 6278 |
| FGD2 | 6272 |
| NMUR2 | 6200 |
| CCL25 | 6175 |
| PDE1B | 6142 |
| HCRT | 6111 |
| GNAI1 | 6083 |
| P2RY6 | 6034 |
| TAAR5 | 6017 |
| NGEF | 6008 |
| TAS2R19 | 5911 |
| PLPPR5 | 5893 |
| GPER1 | 5884 |
| DRD3 | 5795 |
| GRB2 | 5787 |
| CCR9 | 5762 |
| MCHR2 | 5743 |
| RXFP3 | 5733 |
| SCTR | 5716 |
| CCL28 | 5611 |
| GNAT1 | 5605 |
| CXCL5 | 5599 |
| PDE4C | 5598 |
| MTNR1A | 5586 |
| RHO | 5540 |
| OXER1 | 5454 |
| DGKH | 5384 |
| NMS | 5283 |
| FZD9 | 5227 |
| RHOB | 5215 |
| OXGR1 | 5190 |
| ADGRE1 | 5103 |
| NPY5R | 5059 |
| NTSR2 | 5041 |
| PLCB1 | 4905 |
| PTGDR | 4901 |
| GPR68 | 4847 |
| EDNRA | 4813 |
| HRH1 | 4811 |
| HTR6 | 4765 |
| GRP | 4754 |
| F2RL1 | 4731 |
| GPR20 | 4666 |
| SSTR2 | 4630 |
| MAPK7 | 4610 |
| OPN4 | 4565 |
| NLN | 4563 |
| CCR7 | 4543 |
| GPHB5 | 4542 |
| RLN3 | 4541 |
| CREB1 | 4535 |
| INSL5 | 4503 |
| GPR4 | 4461 |
| AKT3 | 4420 |
| ADRA2B | 4418 |
| CALM1 | 4408 |
| PPP3R1 | 4405 |
| EGFR | 4403 |
| ITSN1 | 4396 |
| GNG2 | 4394 |
| GNG13 | 4355 |
| GRM3 | 4344 |
| GNRH2 | 4329 |
| RGS10 | 4249 |
| CCL17 | 4204 |
| PRKAR2B | 4163 |
| EDNRB | 4156 |
| CAMK2B | 4138 |
| ARHGEF19 | 4103 |
| ARHGEF17 | 4070 |
| WNT6 | 4065 |
| PLEKHG5 | 4041 |
| C5 | 3928 |
| PMCH | 3902 |
| S1PR1 | 3881 |
| SUCNR1 | 3878 |
| GALR2 | 3874 |
| GNA13 | 3860 |
| TAC1 | 3845 |
| GNAT3 | 3829 |
| GRM6 | 3825 |
| RPS6KA2 | 3816 |
| ARHGEF4 | 3746 |
| DRD1 | 3735 |
| GRM4 | 3717 |
| PRKCA | 3665 |
| XCL1 | 3619 |
| PRKCE | 3573 |
| PLCB3 | 3506 |
| TRPC3 | 3504 |
| S1PR3 | 3488 |
| ABHD12 | 3472 |
| ARHGEF11 | 3458 |
| RAMP1 | 3436 |
| PTGFR | 3434 |
| ADCY6 | 3433 |
| PTGER3 | 3410 |
| PRLHR | 3347 |
| PLEKHG2 | 3308 |
| CCR3 | 3198 |
| FGD3 | 3197 |
| ADCY9 | 3186 |
| ARHGEF2 | 3130 |
| GPBAR1 | 3116 |
| RASGRF2 | 3042 |
| GPR25 | 3040 |
| CXCL9 | 3013 |
| ARRB2 | 3002 |
| PNOC | 2919 |
| GNA12 | 2882 |
| ADRB3 | 2878 |
| FZD4 | 2821 |
| FN1 | 2815 |
| PLCB4 | 2798 |
| TRPC7 | 2778 |
| HTR4 | 2759 |
| F2 | 2752 |
| TAS1R1 | 2741 |
| CAMKK2 | 2708 |
| HTR5A | 2702 |
| ARRB1 | 2670 |
| GPR15 | 2614 |
| TAS2R30 | 2592 |
| PPP3CA | 2590 |
| WNT7A | 2518 |
| TAS2R40 | 2447 |
| ARHGEF3 | 2445 |
| GHRL | 2350 |
| RGR | 2349 |
| PDPK1 | 2289 |
| RGS7 | 2275 |
| DGKQ | 2251 |
| MC2R | 2199 |
| GNG11 | 2196 |
| GPSM1 | 2159 |
| KALRN | 2090 |
| ADCY8 | 1989 |
| RASGRP1 | 1955 |
| OPRD1 | 1938 |
| HTR1D | 1919 |
| RGS12 | 1889 |
| PIK3CA | 1864 |
| TRIO | 1848 |
| CCL27 | 1818 |
| ITPR3 | 1792 |
| TAS2R1 | 1759 |
| CALCA | 1727 |
| GPR176 | 1705 |
| NPSR1 | 1687 |
| TBXA2R | 1659 |
| WNT7B | 1596 |
| AKT2 | 1521 |
| CXCR2 | 1512 |
| RGS20 | 1499 |
| CCKAR | 1420 |
| TAS2R38 | 1397 |
| ARHGEF12 | 1387 |
| ADCY4 | 1319 |
| PDE7A | 1286 |
| HTR1F | 1259 |
| GAL | 1250 |
| NMUR1 | 1206 |
| HCAR2 | 1147 |
| ADCYAP1 | 1080 |
| PDE4B | 1061 |
| RGS14 | 1007 |
| ADCY7 | 992 |
| ADCY1 | 877 |
| ARHGEF10L | 875 |
| PDE4D | 866 |
| CXCL10 | 840 |
| ADRB2 | 768 |
| TRH | 767 |
| PDE10A | 736 |
| QRFP | 726 |
| ADRA1D | 722 |
| RGS22 | 707 |
| GABBR2 | 677 |
| PDE11A | 485 |
| APLNR | 419 |
| MC5R | 388 |
| LPAR2 | 380 |
| S1PR4 | 364 |
| SHC1 | 356 |
| PDYN | 352 |
| PDE1A | 346 |
| ADGRE2 | 285 |
| SHH | 248 |
| GABBR1 | 239 |
| SOS2 | 203 |
| GNAL | 162 |
| PSAP | 108 |
| PRKCQ | 41 |
| WNT2 | 29 |
| PIK3CG | 14 |
| CXCL8 | 1 |
| PIK3R6 | -11 |
| HTR1A | -89 |
| WNT2B | -94 |
| GPR17 | -95 |
| ADCY2 | -102 |
| GNGT1 | -114 |
| GNB3 | -122 |
| CXCL6 | -155 |
| ARHGEF26 | -162 |
| GRM8 | -198 |
| OPN3 | -217 |
| UCN3 | -264 |
| HCRTR1 | -268 |
| BDKRB2 | -293 |
| CXCR4 | -294 |
| FZD5 | -328 |
| LPAR6 | -365 |
| RRH | -371 |
| OXTR | -380 |
| KEL | -403 |
| WNT16 | -500 |
| DGKA | -538 |
| GNG5 | -594 |
| CHRM3 | -713 |
| HTR7 | -726 |
| NMB | -786 |
| WNT9A | -849 |
| PDE1C | -896 |
| GLP2R | -902 |
| CALCR | -908 |
| ITPR1 | -933 |
| TAS2R46 | -936 |
| AKAP13 | -1001 |
| TAS2R20 | -1014 |
| SOS1 | -1037 |
| GPR37 | -1067 |
| GNG12 | -1102 |
| VAV2 | -1107 |
| VIPR1 | -1262 |
| FGD4 | -1279 |
| GCG | -1283 |
| TAS2R7 | -1322 |
| CASR | -1411 |
| XCR1 | -1413 |
| RGS2 | -1423 |
| HBEGF | -1424 |
| IHH | -1445 |
| DGKI | -1454 |
| NBEA | -1471 |
| CRHR1 | -1513 |
| ARHGEF40 | -1521 |
| FFAR4 | -1584 |
| KPNA2 | -1606 |
| XCL2 | -1654 |
| PLXNB1 | -1662 |
| PDE3A | -1681 |
| GNG10 | -1690 |
| TIAM2 | -1750 |
| ECT2 | -1893 |
| ARHGEF38 | -1900 |
| TAAR6 | -1932 |
| DGKD | -1957 |
| FSHR | -1962 |
| ITPR2 | -1996 |
| PLPPR1 | -2003 |
| TAS1R3 | -2021 |
| ADORA2B | -2062 |
| GNA14 | -2118 |
| FZD7 | -2121 |
| CX3CR1 | -2125 |
| DGKZ | -2240 |
| LHB | -2264 |
| AVPR1A | -2336 |
| GPR39 | -2371 |
| ADORA3 | -2510 |
| PPP2CB | -2525 |
| PROK1 | -2566 |
| CDK5 | -2619 |
| CAMK2D | -2651 |
| RGS3 | -2742 |
| TAS2R13 | -2746 |
| OBSCN | -2752 |
| VAV3 | -2783 |
| C5AR1 | -2800 |
| OPRL1 | -2816 |
| CCKBR | -2845 |
| GNAI3 | -2862 |
| ECE1 | -2935 |
| PPP2R1A | -2973 |
| WNT1 | -2983 |
| HCRTR2 | -2995 |
| RGS19 | -3035 |
| FFAR3 | -3039 |
| CCL2 | -3077 |
| TAS2R43 | -3090 |
| ARHGEF18 | -3122 |
| PTH2 | -3206 |
| CRHR2 | -3207 |
| FZD3 | -3247 |
| ROCK1 | -3299 |
| GPSM2 | -3325 |
| PROK2 | -3326 |
| ADORA1 | -3347 |
| OPN5 | -3381 |
| GPR132 | -3406 |
| ABR | -3418 |
| CAMK2G | -3421 |
| ARHGEF16 | -3461 |
| RGS5 | -3469 |
| UTS2R | -3473 |
| GHSR | -3477 |
| PPP3CB | -3495 |
| GPSM3 | -3497 |
| CRHBP | -3533 |
| ARHGEF7 | -3549 |
| ARHGEF1 | -3554 |
| ADCY3 | -3624 |
| NPFFR1 | -3632 |
| PIK3R1 | -3634 |
| ITGA5 | -3638 |
| CMKLR1 | -3650 |
| MC1R | -3657 |
| PDE8A | -3691 |
| NPFF | -3793 |
| CCL19 | -3829 |
| RGS6 | -3844 |
| MTNR1B | -3861 |
| UCN | -3903 |
| NMU | -3969 |
| EDN3 | -3991 |
| SRC | -4047 |
| PRKACG | -4062 |
| GRM7 | -4083 |
| RGS16 | -4097 |
| ROCK2 | -4141 |
| GNA11 | -4159 |
| PTCH1 | -4169 |
| PRKAR1B | -4290 |
| MCF2L | -4308 |
| PRKCD | -4339 |
| P2RY12 | -4362 |
| PDE4A | -4412 |
| DGKB | -4419 |
| NPBWR1 | -4420 |
| CCR5 | -4441 |
| NPB | -4452 |
| ADM2 | -4587 |
| RGS4 | -4600 |
| TAS2R39 | -4617 |
| FPR2 | -4671 |
| TIAM1 | -4675 |
| AGTR1 | -4681 |
| PIK3R5 | -4744 |
| GNG3 | -4759 |
| RASGRP2 | -4794 |
| DRD4 | -4824 |
| CHRM1 | -4837 |
| GHRHR | -4859 |
| NPW | -4860 |
| HTR2B | -4867 |
| CXCL2 | -4895 |
| PYY | -4900 |
| GPR35 | -5007 |
| PTHLH | -5054 |
| CXCL16 | -5103 |
| FPR1 | -5112 |
| VIP | -5116 |
| GPR55 | -5124 |
| VAV1 | -5192 |
| RXFP4 | -5260 |
| PDE2A | -5269 |
| GPR37L1 | -5302 |
| RHOC | -5306 |
| GLP1R | -5314 |
| TAS1R2 | -5365 |
| GNG4 | -5388 |
| FZD2 | -5428 |
| PRKACA | -5493 |
| PAK1 | -5494 |
| PPP3CC | -5608 |
| CAMK4 | -5681 |
| PRKCG | -5710 |
| APP | -5711 |
| PRKACB | -5745 |
| ARHGEF10 | -5761 |
| GRK5 | -5875 |
| PIK3R3 | -5912 |
| GNAQ | -5998 |
| MAPK1 | -6079 |
| DGKG | -6092 |
| SMO | -6182 |
| WNT9B | -6226 |
| KNG1 | -6316 |
| GRM5 | -6378 |
| ADRB1 | -6400 |
| GNRHR | -6432 |
| EDN1 | -6433 |
| PLCB2 | -6460 |
| NTS | -6474 |
| GPR65 | -6548 |
| PRKCB | -6551 |
| GNAS | -6556 |
| MLN | -6577 |
| TACR1 | -6605 |
| DAGLB | -6811 |
| TSHB | -6843 |
| PTH2R | -6938 |
| WNT11 | -6994 |
| CHRM2 | -7066 |
| S1PR5 | -7083 |
| PTGER1 | -7091 |
| GRK3 | -7179 |
| LPAR3 | -7203 |
| ARHGEF15 | -7324 |
| PRKAR1A | -7361 |
| RGS17 | -7394 |
| ABHD6 | -7412 |
| P2RY13 | -7438 |
| TSHR | -7514 |
| SSTR5 | -7613 |
| GNB4 | -7626 |
| AHCYL1 | -7708 |
| TACR2 | -7849 |
| CHRM5 | -7863 |
| WNT8B | -7904 |
| PTAFR | -7971 |
| RAMP3 | -7975 |
| RHOA | -7993 |
| TAS2R42 | -8167 |
| TAS2R41 | -8174 |
| PTGER4 | -8181 |
| RPS6KA1 | -8254 |
| RLN2 | -8288 |
| CXCL3 | -8299 |
| CORT | -8356 |
| TAS2R3 | -8359 |
| HEBP1 | -8411 |
| TAS2R31 | -8433 |
| PTGER2 | -8440 |
| CNR2 | -8482 |
| GPR84 | -8494 |
| CALCB | -8497 |
| PDE7B | -8552 |
| FFAR1 | -8675 |
| WNT10B | -8708 |
| TAS2R16 | -8745 |
| GPR27 | -8774 |
| ECE2 | -8809 |
| GNB2 | -8837 |
| GPRC6A | -8858 |
| GNB5 | -8860 |
| VIPR2 | -8862 |
| PCP2 | -8983 |
| UTS2B | -9001 |
| GNG7 | -9020 |
| GIP | -9032 |
| NRAS | -9056 |
| NET1 | -9062 |
| INSL3 | -9149 |
| PPY | -9221 |
| KISS1 | -9276 |
| OXT | -9288 |
| TAS2R10 | -9301 |
| PPP2CA | -9312 |
| CCL11 | -9384 |
| PIK3R2 | -9400 |
| GALR3 | -9447 |
| PPP2R5D | -9565 |
| F2RL2 | -9581 |
| PLPPR2 | -9626 |
| OPN1SW | -9689 |
| RGS9 | -9693 |
| PROKR2 | -9728 |
| GRK2 | -9768 |
| CAMKK1 | -9782 |
| PTCH2 | -9792 |
| F2RL3 | -9874 |
| GNG8 | -9902 |
| PRKAR2A | -9917 |
| GPR32 | -10004 |
| NPBWR2 | -10033 |
| GPHA2 | -10098 |
| P2RY11 | -10112 |
| KRAS | -10121 |
| ARHGEF39 | -10168 |
| CYSLTR2 | -10187 |
| ACKR2 | -10236 |
| ITGB1 | -10255 |
| CCR8 | -10260 |
| RGS18 | -10526 |
| QRFPR | -10577 |
| IAPP | -10644 |
| MC4R | -10716 |
| S1PR2 | -10717 |
| TAS2R4 | -10725 |
| DGKE | -10893 |
| C5AR2 | -10895 |
| CXCL11 | -10904 |
| TAS2R14 | -10916 |
| TAC3 | -10924 |
| GNRH1 | -10936 |
| ARHGEF5 | -10975 |
| HTR2A | -10995 |
| GIPR | -11018 |
| AGT | -11085 |
| CCL3 | -11116 |
| MCHR1 | -11205 |
| FSHB | -11209 |
| SSTR3 | -11225 |
| TAAR9 | -11277 |
| HRH4 | -11329 |
| AVP | -11350 |
| TAS2R60 | -11412 |
| CX3CL1 | -11454 |
| ANXA1 | -11455 |
| PTGIR | -11597 |
| ACKR4 | -11776 |
REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS
| 594 | |
|---|---|
| set | REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS |
| setSize | 312 |
| pANOVA | 1.32e-06 |
| s.dist | 0.159 |
| p.adjustANOVA | 0.00108 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| LPAR5 | 10090 |
| CCL22 | 10065 |
| DRD5 | 10061 |
| SAA1 | 10054 |
| CCL4 | 10026 |
| CCL5 | 10003 |
| CXCR6 | 9994 |
| TAAR8 | 9991 |
| CXCL1 | 9982 |
| CCR2 | 9938 |
| CCR6 | 9905 |
| CXCR5 | 9845 |
| TAAR1 | 9837 |
| SSTR4 | 9810 |
| CCL13 | 9779 |
| HCAR1 | 9717 |
| CCL1 | 9680 |
| TRHR | 9561 |
| CCRL2 | 9506 |
| C3AR1 | 9470 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| LPAR5 | 10090 |
| CCL22 | 10065 |
| DRD5 | 10061 |
| SAA1 | 10054 |
| CCL4 | 10026 |
| CCL5 | 10003 |
| CXCR6 | 9994 |
| TAAR8 | 9991 |
| CXCL1 | 9982 |
| CCR2 | 9938 |
| CCR6 | 9905 |
| CXCR5 | 9845 |
| TAAR1 | 9837 |
| SSTR4 | 9810 |
| CCL13 | 9779 |
| HCAR1 | 9717 |
| CCL1 | 9680 |
| TRHR | 9561 |
| CCRL2 | 9506 |
| C3AR1 | 9470 |
| FPR3 | 9433 |
| PPBP | 9375 |
| SSTR1 | 9359 |
| ACKR3 | 9342 |
| CCL16 | 9292 |
| HRH3 | 9245 |
| PTGDR2 | 9100 |
| GPR18 | 9057 |
| CCL20 | 9053 |
| GPR183 | 9033 |
| ADRA2C | 9020 |
| ADRA1B | 9009 |
| LTB4R | 8989 |
| CXCR1 | 8889 |
| CHRM4 | 8860 |
| NTSR1 | 8849 |
| C3 | 8800 |
| EDN2 | 8784 |
| ADORA2A | 8757 |
| CCL7 | 8746 |
| ADRA1A | 8688 |
| MC3R | 8676 |
| P2RY1 | 8671 |
| PLPPR3 | 8655 |
| FFAR2 | 8598 |
| CCL23 | 8588 |
| HTR1B | 8578 |
| BDKRB1 | 8451 |
| CNR1 | 8445 |
| LTB4R2 | 8441 |
| GPR31 | 8287 |
| CCL21 | 8262 |
| PRLH | 8256 |
| CGA | 8227 |
| NPY2R | 8212 |
| MLNR | 8089 |
| SST | 8074 |
| TACR3 | 8070 |
| LHCGR | 8052 |
| DRD2 | 8046 |
| GALR1 | 8027 |
| CCK | 7953 |
| CCR1 | 7916 |
| HTR1E | 7901 |
| PF4 | 7738 |
| RXFP1 | 7693 |
| LPAR1 | 7692 |
| AVPR1B | 7655 |
| PLPPR4 | 7652 |
| F2R | 7565 |
| NPFFR2 | 7469 |
| ADRA2A | 7409 |
| CXCL13 | 7397 |
| OPRM1 | 7376 |
| HRH2 | 7342 |
| NPY1R | 7272 |
| ACKR1 | 7270 |
| UTS2 | 7196 |
| NPY | 7117 |
| NPS | 7072 |
| POMC | 7031 |
| PROKR1 | 7028 |
| OPRK1 | 7013 |
| P2RY2 | 6949 |
| PENK | 6920 |
| CCR10 | 6837 |
| NMBR | 6781 |
| CXCL12 | 6660 |
| TAAR2 | 6657 |
| RXFP2 | 6654 |
| CCR4 | 6538 |
| KISS1R | 6441 |
| P2RY14 | 6278 |
| NMUR2 | 6200 |
| CCL25 | 6175 |
| HCRT | 6111 |
| P2RY6 | 6034 |
| TAAR5 | 6017 |
| PLPPR5 | 5893 |
| GPER1 | 5884 |
| DRD3 | 5795 |
| CCR9 | 5762 |
| MCHR2 | 5743 |
| RXFP3 | 5733 |
| CCL28 | 5611 |
| CXCL5 | 5599 |
| MTNR1A | 5586 |
| RHO | 5540 |
| OXER1 | 5454 |
| NMS | 5283 |
| OXGR1 | 5190 |
| NPY5R | 5059 |
| NTSR2 | 5041 |
| PTGDR | 4901 |
| GPR68 | 4847 |
| EDNRA | 4813 |
| HRH1 | 4811 |
| HTR6 | 4765 |
| GRP | 4754 |
| F2RL1 | 4731 |
| SSTR2 | 4630 |
| OPN4 | 4565 |
| NLN | 4563 |
| CCR7 | 4543 |
| GPHB5 | 4542 |
| RLN3 | 4541 |
| INSL5 | 4503 |
| GPR4 | 4461 |
| ADRA2B | 4418 |
| GNRH2 | 4329 |
| CCL17 | 4204 |
| EDNRB | 4156 |
| C5 | 3928 |
| PMCH | 3902 |
| S1PR1 | 3881 |
| SUCNR1 | 3878 |
| GALR2 | 3874 |
| TAC1 | 3845 |
| DRD1 | 3735 |
| XCL1 | 3619 |
| S1PR3 | 3488 |
| PTGFR | 3434 |
| PTGER3 | 3410 |
| PRLHR | 3347 |
| CCR3 | 3198 |
| GPBAR1 | 3116 |
| CXCL9 | 3013 |
| PNOC | 2919 |
| ADRB3 | 2878 |
| HTR4 | 2759 |
| F2 | 2752 |
| HTR5A | 2702 |
| GHRL | 2350 |
| RGR | 2349 |
| MC2R | 2199 |
| OPRD1 | 1938 |
| HTR1D | 1919 |
| CCL27 | 1818 |
| NPSR1 | 1687 |
| TBXA2R | 1659 |
| CXCR2 | 1512 |
| CCKAR | 1420 |
| HTR1F | 1259 |
| GAL | 1250 |
| NMUR1 | 1206 |
| HCAR2 | 1147 |
| CXCL10 | 840 |
| ADRB2 | 768 |
| TRH | 767 |
| QRFP | 726 |
| ADRA1D | 722 |
| APLNR | 419 |
| MC5R | 388 |
| LPAR2 | 380 |
| S1PR4 | 364 |
| PDYN | 352 |
| PSAP | 108 |
| CXCL8 | 1 |
| HTR1A | -89 |
| GPR17 | -95 |
| CXCL6 | -155 |
| OPN3 | -217 |
| HCRTR1 | -268 |
| BDKRB2 | -293 |
| CXCR4 | -294 |
| LPAR6 | -365 |
| RRH | -371 |
| OXTR | -380 |
| KEL | -403 |
| CHRM3 | -713 |
| HTR7 | -726 |
| NMB | -786 |
| GPR37 | -1067 |
| XCR1 | -1413 |
| FFAR4 | -1584 |
| XCL2 | -1654 |
| TAAR6 | -1932 |
| FSHR | -1962 |
| PLPPR1 | -2003 |
| ADORA2B | -2062 |
| CX3CR1 | -2125 |
| LHB | -2264 |
| AVPR1A | -2336 |
| GPR39 | -2371 |
| ADORA3 | -2510 |
| PROK1 | -2566 |
| C5AR1 | -2800 |
| OPRL1 | -2816 |
| CCKBR | -2845 |
| ECE1 | -2935 |
| HCRTR2 | -2995 |
| FFAR3 | -3039 |
| CCL2 | -3077 |
| PROK2 | -3326 |
| ADORA1 | -3347 |
| OPN5 | -3381 |
| GPR132 | -3406 |
| UTS2R | -3473 |
| GHSR | -3477 |
| NPFFR1 | -3632 |
| CMKLR1 | -3650 |
| MC1R | -3657 |
| NPFF | -3793 |
| CCL19 | -3829 |
| MTNR1B | -3861 |
| NMU | -3969 |
| EDN3 | -3991 |
| P2RY12 | -4362 |
| NPBWR1 | -4420 |
| CCR5 | -4441 |
| NPB | -4452 |
| FPR2 | -4671 |
| AGTR1 | -4681 |
| DRD4 | -4824 |
| CHRM1 | -4837 |
| NPW | -4860 |
| HTR2B | -4867 |
| CXCL2 | -4895 |
| PYY | -4900 |
| GPR35 | -5007 |
| CXCL16 | -5103 |
| FPR1 | -5112 |
| GPR55 | -5124 |
| RXFP4 | -5260 |
| GPR37L1 | -5302 |
| APP | -5711 |
| KNG1 | -6316 |
| ADRB1 | -6400 |
| GNRHR | -6432 |
| EDN1 | -6433 |
| NTS | -6474 |
| GPR65 | -6548 |
| MLN | -6577 |
| TACR1 | -6605 |
| TSHB | -6843 |
| CHRM2 | -7066 |
| S1PR5 | -7083 |
| PTGER1 | -7091 |
| LPAR3 | -7203 |
| P2RY13 | -7438 |
| TSHR | -7514 |
| SSTR5 | -7613 |
| TACR2 | -7849 |
| CHRM5 | -7863 |
| PTAFR | -7971 |
| PTGER4 | -8181 |
| RLN2 | -8288 |
| CXCL3 | -8299 |
| CORT | -8356 |
| HEBP1 | -8411 |
| PTGER2 | -8440 |
| CNR2 | -8482 |
| FFAR1 | -8675 |
| ECE2 | -8809 |
| UTS2B | -9001 |
| INSL3 | -9149 |
| PPY | -9221 |
| KISS1 | -9276 |
| OXT | -9288 |
| CCL11 | -9384 |
| GALR3 | -9447 |
| F2RL2 | -9581 |
| PLPPR2 | -9626 |
| OPN1SW | -9689 |
| PROKR2 | -9728 |
| F2RL3 | -9874 |
| NPBWR2 | -10033 |
| GPHA2 | -10098 |
| P2RY11 | -10112 |
| CYSLTR2 | -10187 |
| ACKR2 | -10236 |
| CCR8 | -10260 |
| QRFPR | -10577 |
| MC4R | -10716 |
| S1PR2 | -10717 |
| C5AR2 | -10895 |
| CXCL11 | -10904 |
| TAC3 | -10924 |
| GNRH1 | -10936 |
| HTR2A | -10995 |
| AGT | -11085 |
| CCL3 | -11116 |
| MCHR1 | -11205 |
| FSHB | -11209 |
| SSTR3 | -11225 |
| TAAR9 | -11277 |
| HRH4 | -11329 |
| AVP | -11350 |
| CX3CL1 | -11454 |
| ANXA1 | -11455 |
| PTGIR | -11597 |
| ACKR4 | -11776 |
REACTOME_GPCR_LIGAND_BINDING
| 834 | |
|---|---|
| set | REACTOME_GPCR_LIGAND_BINDING |
| setSize | 444 |
| pANOVA | 2.98e-06 |
| s.dist | 0.129 |
| p.adjustANOVA | 0.00163 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| LPAR5 | 10090 |
| CCL22 | 10065 |
| DRD5 | 10061 |
| SAA1 | 10054 |
| GNGT2 | 10053 |
| CCL4 | 10026 |
| CCL5 | 10003 |
| CXCR6 | 9994 |
| TAAR8 | 9991 |
| CXCL1 | 9982 |
| GHRH | 9950 |
| CCR2 | 9938 |
| CCR6 | 9905 |
| TAS2R8 | 9890 |
| CXCR5 | 9845 |
| TAAR1 | 9837 |
| SSTR4 | 9810 |
| CCL13 | 9779 |
| HCAR1 | 9717 |
| CCL1 | 9680 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| LPAR5 | 10090 |
| CCL22 | 10065 |
| DRD5 | 10061 |
| SAA1 | 10054 |
| GNGT2 | 10053 |
| CCL4 | 10026 |
| CCL5 | 10003 |
| CXCR6 | 9994 |
| TAAR8 | 9991 |
| CXCL1 | 9982 |
| GHRH | 9950 |
| CCR2 | 9938 |
| CCR6 | 9905 |
| TAS2R8 | 9890 |
| CXCR5 | 9845 |
| TAAR1 | 9837 |
| SSTR4 | 9810 |
| CCL13 | 9779 |
| HCAR1 | 9717 |
| CCL1 | 9680 |
| TAS2R9 | 9605 |
| TRHR | 9561 |
| CCRL2 | 9506 |
| C3AR1 | 9470 |
| FZD8 | 9445 |
| FPR3 | 9433 |
| TAS2R5 | 9406 |
| PPBP | 9375 |
| ADGRE3 | 9363 |
| SSTR1 | 9359 |
| ACKR3 | 9342 |
| CCL16 | 9292 |
| ADCYAP1R1 | 9287 |
| SCT | 9247 |
| HRH3 | 9245 |
| PTGDR2 | 9100 |
| GPR18 | 9057 |
| RAMP2 | 9056 |
| CCL20 | 9053 |
| GPR183 | 9033 |
| ADRA2C | 9020 |
| ADRA1B | 9009 |
| LTB4R | 8989 |
| WNT10A | 8898 |
| CXCR1 | 8889 |
| CHRM4 | 8860 |
| NTSR1 | 8849 |
| C3 | 8800 |
| EDN2 | 8784 |
| ADORA2A | 8757 |
| CCL7 | 8746 |
| ADRA1A | 8688 |
| MC3R | 8676 |
| P2RY1 | 8671 |
| PLPPR3 | 8655 |
| FFAR2 | 8598 |
| CCL23 | 8588 |
| HTR1B | 8578 |
| FZD10 | 8520 |
| GRM1 | 8496 |
| ADGRE5 | 8456 |
| BDKRB1 | 8451 |
| CNR1 | 8445 |
| LTB4R2 | 8441 |
| FZD6 | 8371 |
| CALCRL | 8299 |
| GPR31 | 8287 |
| CCL21 | 8262 |
| PRLH | 8256 |
| CGA | 8227 |
| NPY2R | 8212 |
| MLNR | 8089 |
| SST | 8074 |
| TACR3 | 8070 |
| LHCGR | 8052 |
| DRD2 | 8046 |
| FZD1 | 8043 |
| GALR1 | 8027 |
| WNT3 | 8005 |
| CRH | 7998 |
| CCK | 7953 |
| CCR1 | 7916 |
| HTR1E | 7901 |
| UCN2 | 7840 |
| PF4 | 7738 |
| RXFP1 | 7693 |
| LPAR1 | 7692 |
| AVPR1B | 7655 |
| PLPPR4 | 7652 |
| TAS2R50 | 7568 |
| F2R | 7565 |
| NPFFR2 | 7469 |
| ADRA2A | 7409 |
| CXCL13 | 7397 |
| OPRM1 | 7376 |
| HRH2 | 7342 |
| WNT4 | 7338 |
| NPY1R | 7272 |
| ACKR1 | 7270 |
| UTS2 | 7196 |
| WNT8A | 7194 |
| GRM2 | 7138 |
| WNT5A | 7123 |
| NPY | 7117 |
| CD55 | 7097 |
| NPS | 7072 |
| POMC | 7031 |
| PROKR1 | 7028 |
| OPRK1 | 7013 |
| P2RY2 | 6949 |
| WNT3A | 6948 |
| PENK | 6920 |
| CCR10 | 6837 |
| ADM | 6796 |
| NMBR | 6781 |
| CXCL12 | 6660 |
| TAAR2 | 6657 |
| RXFP2 | 6654 |
| DHH | 6641 |
| GNB1 | 6594 |
| PTH | 6578 |
| CCR4 | 6538 |
| KISS1R | 6441 |
| PTH1R | 6290 |
| P2RY14 | 6278 |
| NMUR2 | 6200 |
| CCL25 | 6175 |
| HCRT | 6111 |
| P2RY6 | 6034 |
| TAAR5 | 6017 |
| TAS2R19 | 5911 |
| PLPPR5 | 5893 |
| GPER1 | 5884 |
| DRD3 | 5795 |
| CCR9 | 5762 |
| MCHR2 | 5743 |
| RXFP3 | 5733 |
| SCTR | 5716 |
| CCL28 | 5611 |
| CXCL5 | 5599 |
| MTNR1A | 5586 |
| RHO | 5540 |
| OXER1 | 5454 |
| NMS | 5283 |
| FZD9 | 5227 |
| OXGR1 | 5190 |
| ADGRE1 | 5103 |
| NPY5R | 5059 |
| NTSR2 | 5041 |
| PTGDR | 4901 |
| GPR68 | 4847 |
| EDNRA | 4813 |
| HRH1 | 4811 |
| HTR6 | 4765 |
| GRP | 4754 |
| F2RL1 | 4731 |
| SSTR2 | 4630 |
| OPN4 | 4565 |
| NLN | 4563 |
| CCR7 | 4543 |
| GPHB5 | 4542 |
| RLN3 | 4541 |
| INSL5 | 4503 |
| GPR4 | 4461 |
| ADRA2B | 4418 |
| GNG2 | 4394 |
| GNG13 | 4355 |
| GRM3 | 4344 |
| GNRH2 | 4329 |
| CCL17 | 4204 |
| EDNRB | 4156 |
| WNT6 | 4065 |
| C5 | 3928 |
| PMCH | 3902 |
| S1PR1 | 3881 |
| SUCNR1 | 3878 |
| GALR2 | 3874 |
| TAC1 | 3845 |
| GRM6 | 3825 |
| DRD1 | 3735 |
| GRM4 | 3717 |
| XCL1 | 3619 |
| S1PR3 | 3488 |
| RAMP1 | 3436 |
| PTGFR | 3434 |
| PTGER3 | 3410 |
| PRLHR | 3347 |
| CCR3 | 3198 |
| GPBAR1 | 3116 |
| CXCL9 | 3013 |
| PNOC | 2919 |
| ADRB3 | 2878 |
| FZD4 | 2821 |
| HTR4 | 2759 |
| F2 | 2752 |
| TAS1R1 | 2741 |
| HTR5A | 2702 |
| TAS2R30 | 2592 |
| WNT7A | 2518 |
| TAS2R40 | 2447 |
| GHRL | 2350 |
| RGR | 2349 |
| MC2R | 2199 |
| GNG11 | 2196 |
| OPRD1 | 1938 |
| HTR1D | 1919 |
| CCL27 | 1818 |
| TAS2R1 | 1759 |
| CALCA | 1727 |
| NPSR1 | 1687 |
| TBXA2R | 1659 |
| WNT7B | 1596 |
| CXCR2 | 1512 |
| CCKAR | 1420 |
| TAS2R38 | 1397 |
| HTR1F | 1259 |
| GAL | 1250 |
| NMUR1 | 1206 |
| HCAR2 | 1147 |
| ADCYAP1 | 1080 |
| CXCL10 | 840 |
| ADRB2 | 768 |
| TRH | 767 |
| QRFP | 726 |
| ADRA1D | 722 |
| GABBR2 | 677 |
| APLNR | 419 |
| MC5R | 388 |
| LPAR2 | 380 |
| S1PR4 | 364 |
| PDYN | 352 |
| ADGRE2 | 285 |
| SHH | 248 |
| GABBR1 | 239 |
| PSAP | 108 |
| WNT2 | 29 |
| CXCL8 | 1 |
| HTR1A | -89 |
| WNT2B | -94 |
| GPR17 | -95 |
| GNGT1 | -114 |
| GNB3 | -122 |
| CXCL6 | -155 |
| GRM8 | -198 |
| OPN3 | -217 |
| UCN3 | -264 |
| HCRTR1 | -268 |
| BDKRB2 | -293 |
| CXCR4 | -294 |
| FZD5 | -328 |
| LPAR6 | -365 |
| RRH | -371 |
| OXTR | -380 |
| KEL | -403 |
| WNT16 | -500 |
| GNG5 | -594 |
| CHRM3 | -713 |
| HTR7 | -726 |
| NMB | -786 |
| WNT9A | -849 |
| GLP2R | -902 |
| CALCR | -908 |
| TAS2R46 | -936 |
| TAS2R20 | -1014 |
| GPR37 | -1067 |
| GNG12 | -1102 |
| VIPR1 | -1262 |
| GCG | -1283 |
| TAS2R7 | -1322 |
| CASR | -1411 |
| XCR1 | -1413 |
| IHH | -1445 |
| CRHR1 | -1513 |
| FFAR4 | -1584 |
| XCL2 | -1654 |
| GNG10 | -1690 |
| TAAR6 | -1932 |
| FSHR | -1962 |
| PLPPR1 | -2003 |
| TAS1R3 | -2021 |
| ADORA2B | -2062 |
| FZD7 | -2121 |
| CX3CR1 | -2125 |
| LHB | -2264 |
| AVPR1A | -2336 |
| GPR39 | -2371 |
| ADORA3 | -2510 |
| PROK1 | -2566 |
| TAS2R13 | -2746 |
| C5AR1 | -2800 |
| OPRL1 | -2816 |
| CCKBR | -2845 |
| ECE1 | -2935 |
| WNT1 | -2983 |
| HCRTR2 | -2995 |
| FFAR3 | -3039 |
| CCL2 | -3077 |
| TAS2R43 | -3090 |
| PTH2 | -3206 |
| CRHR2 | -3207 |
| FZD3 | -3247 |
| PROK2 | -3326 |
| ADORA1 | -3347 |
| OPN5 | -3381 |
| GPR132 | -3406 |
| UTS2R | -3473 |
| GHSR | -3477 |
| CRHBP | -3533 |
| NPFFR1 | -3632 |
| CMKLR1 | -3650 |
| MC1R | -3657 |
| NPFF | -3793 |
| CCL19 | -3829 |
| MTNR1B | -3861 |
| UCN | -3903 |
| NMU | -3969 |
| EDN3 | -3991 |
| GRM7 | -4083 |
| PTCH1 | -4169 |
| P2RY12 | -4362 |
| NPBWR1 | -4420 |
| CCR5 | -4441 |
| NPB | -4452 |
| ADM2 | -4587 |
| TAS2R39 | -4617 |
| FPR2 | -4671 |
| AGTR1 | -4681 |
| GNG3 | -4759 |
| DRD4 | -4824 |
| CHRM1 | -4837 |
| GHRHR | -4859 |
| NPW | -4860 |
| HTR2B | -4867 |
| CXCL2 | -4895 |
| PYY | -4900 |
| GPR35 | -5007 |
| PTHLH | -5054 |
| CXCL16 | -5103 |
| FPR1 | -5112 |
| VIP | -5116 |
| GPR55 | -5124 |
| RXFP4 | -5260 |
| GPR37L1 | -5302 |
| GLP1R | -5314 |
| TAS1R2 | -5365 |
| GNG4 | -5388 |
| FZD2 | -5428 |
| APP | -5711 |
| SMO | -6182 |
| WNT9B | -6226 |
| KNG1 | -6316 |
| GRM5 | -6378 |
| ADRB1 | -6400 |
| GNRHR | -6432 |
| EDN1 | -6433 |
| NTS | -6474 |
| GPR65 | -6548 |
| GNAS | -6556 |
| MLN | -6577 |
| TACR1 | -6605 |
| TSHB | -6843 |
| PTH2R | -6938 |
| WNT11 | -6994 |
| CHRM2 | -7066 |
| S1PR5 | -7083 |
| PTGER1 | -7091 |
| LPAR3 | -7203 |
| P2RY13 | -7438 |
| TSHR | -7514 |
| SSTR5 | -7613 |
| GNB4 | -7626 |
| TACR2 | -7849 |
| CHRM5 | -7863 |
| WNT8B | -7904 |
| PTAFR | -7971 |
| RAMP3 | -7975 |
| TAS2R42 | -8167 |
| TAS2R41 | -8174 |
| PTGER4 | -8181 |
| RLN2 | -8288 |
| CXCL3 | -8299 |
| CORT | -8356 |
| TAS2R3 | -8359 |
| HEBP1 | -8411 |
| TAS2R31 | -8433 |
| PTGER2 | -8440 |
| CNR2 | -8482 |
| CALCB | -8497 |
| FFAR1 | -8675 |
| WNT10B | -8708 |
| TAS2R16 | -8745 |
| ECE2 | -8809 |
| GNB2 | -8837 |
| GPRC6A | -8858 |
| GNB5 | -8860 |
| VIPR2 | -8862 |
| UTS2B | -9001 |
| GNG7 | -9020 |
| GIP | -9032 |
| INSL3 | -9149 |
| PPY | -9221 |
| KISS1 | -9276 |
| OXT | -9288 |
| TAS2R10 | -9301 |
| CCL11 | -9384 |
| GALR3 | -9447 |
| F2RL2 | -9581 |
| PLPPR2 | -9626 |
| OPN1SW | -9689 |
| PROKR2 | -9728 |
| PTCH2 | -9792 |
| F2RL3 | -9874 |
| GNG8 | -9902 |
| NPBWR2 | -10033 |
| GPHA2 | -10098 |
| P2RY11 | -10112 |
| CYSLTR2 | -10187 |
| ACKR2 | -10236 |
| CCR8 | -10260 |
| QRFPR | -10577 |
| IAPP | -10644 |
| MC4R | -10716 |
| S1PR2 | -10717 |
| TAS2R4 | -10725 |
| C5AR2 | -10895 |
| CXCL11 | -10904 |
| TAS2R14 | -10916 |
| TAC3 | -10924 |
| GNRH1 | -10936 |
| HTR2A | -10995 |
| GIPR | -11018 |
| AGT | -11085 |
| CCL3 | -11116 |
| MCHR1 | -11205 |
| FSHB | -11209 |
| SSTR3 | -11225 |
| TAAR9 | -11277 |
| HRH4 | -11329 |
| AVP | -11350 |
| TAS2R60 | -11412 |
| CX3CL1 | -11454 |
| ANXA1 | -11455 |
| PTGIR | -11597 |
| ACKR4 | -11776 |
REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES
| 615 | |
|---|---|
| set | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES |
| setSize | 55 |
| pANOVA | 3.08e-05 |
| s.dist | 0.325 |
| p.adjustANOVA | 0.0125 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CCL22 | 10065 |
| CCL4 | 10026 |
| CCL5 | 10003 |
| CXCR6 | 9994 |
| CXCL1 | 9982 |
| CCR2 | 9938 |
| CCR6 | 9905 |
| CXCR5 | 9845 |
| CCL13 | 9779 |
| CCL1 | 9680 |
| CCRL2 | 9506 |
| PPBP | 9375 |
| ACKR3 | 9342 |
| CCL16 | 9292 |
| CCL20 | 9053 |
| CXCR1 | 8889 |
| CCL7 | 8746 |
| CCL21 | 8262 |
| CCR1 | 7916 |
| PF4 | 7738 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CCL22 | 10065 |
| CCL4 | 10026 |
| CCL5 | 10003 |
| CXCR6 | 9994 |
| CXCL1 | 9982 |
| CCR2 | 9938 |
| CCR6 | 9905 |
| CXCR5 | 9845 |
| CCL13 | 9779 |
| CCL1 | 9680 |
| CCRL2 | 9506 |
| PPBP | 9375 |
| ACKR3 | 9342 |
| CCL16 | 9292 |
| CCL20 | 9053 |
| CXCR1 | 8889 |
| CCL7 | 8746 |
| CCL21 | 8262 |
| CCR1 | 7916 |
| PF4 | 7738 |
| CXCL13 | 7397 |
| CCR10 | 6837 |
| CXCL12 | 6660 |
| CCR4 | 6538 |
| CCL25 | 6175 |
| CCR9 | 5762 |
| CCL28 | 5611 |
| CXCL5 | 5599 |
| CCR7 | 4543 |
| CCL17 | 4204 |
| XCL1 | 3619 |
| CCR3 | 3198 |
| CXCL9 | 3013 |
| CCL27 | 1818 |
| CXCR2 | 1512 |
| CXCL10 | 840 |
| CXCL8 | 1 |
| CXCL6 | -155 |
| CXCR4 | -294 |
| XCR1 | -1413 |
| XCL2 | -1654 |
| CX3CR1 | -2125 |
| CCL2 | -3077 |
| CCL19 | -3829 |
| CCR5 | -4441 |
| CXCL2 | -4895 |
| CXCL16 | -5103 |
| CXCL3 | -8299 |
| CCL11 | -9384 |
| ACKR2 | -10236 |
| CCR8 | -10260 |
| CXCL11 | -10904 |
| CCL3 | -11116 |
| CX3CL1 | -11454 |
| ACKR4 | -11776 |
REACTOME_G_ALPHA_I_SIGNALLING_EVENTS
| 707 | |
|---|---|
| set | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS |
| setSize | 304 |
| pANOVA | 3.81e-05 |
| s.dist | 0.137 |
| p.adjustANOVA | 0.0125 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| LPAR5 | 10090 |
| SAA1 | 10054 |
| GNGT2 | 10053 |
| GNAT2 | 10030 |
| CCL4 | 10026 |
| CCL5 | 10003 |
| CXCR6 | 9994 |
| CXCL1 | 9982 |
| CCR2 | 9938 |
| CCR6 | 9905 |
| TAS2R8 | 9890 |
| CXCR5 | 9845 |
| SSTR4 | 9810 |
| CCL13 | 9779 |
| HCAR1 | 9717 |
| RGS11 | 9687 |
| CCL1 | 9680 |
| TAS2R9 | 9605 |
| C3AR1 | 9470 |
| FPR3 | 9433 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| LPAR5 | 10090 |
| SAA1 | 10054 |
| GNGT2 | 10053 |
| GNAT2 | 10030 |
| CCL4 | 10026 |
| CCL5 | 10003 |
| CXCR6 | 9994 |
| CXCL1 | 9982 |
| CCR2 | 9938 |
| CCR6 | 9905 |
| TAS2R8 | 9890 |
| CXCR5 | 9845 |
| SSTR4 | 9810 |
| CCL13 | 9779 |
| HCAR1 | 9717 |
| RGS11 | 9687 |
| CCL1 | 9680 |
| TAS2R9 | 9605 |
| C3AR1 | 9470 |
| FPR3 | 9433 |
| TAS2R5 | 9406 |
| RGS21 | 9393 |
| PPBP | 9375 |
| SSTR1 | 9359 |
| GNAI2 | 9357 |
| ACKR3 | 9342 |
| PPP1CA | 9335 |
| CCL16 | 9292 |
| PTGDR2 | 9100 |
| GPR18 | 9057 |
| CCL20 | 9053 |
| GPR183 | 9033 |
| ADRA2C | 9020 |
| CXCR1 | 8889 |
| CHRM4 | 8860 |
| C3 | 8800 |
| CCL23 | 8588 |
| HTR1B | 8578 |
| BDKRB1 | 8451 |
| CNR1 | 8445 |
| GPR31 | 8287 |
| CCL21 | 8262 |
| NPY2R | 8212 |
| GNAZ | 8159 |
| SST | 8074 |
| GALR1 | 8027 |
| CCR1 | 7916 |
| HTR1E | 7901 |
| PF4 | 7738 |
| LPAR1 | 7692 |
| TAS2R50 | 7568 |
| ADRA2A | 7409 |
| CXCL13 | 7397 |
| OPRM1 | 7376 |
| NPY1R | 7272 |
| GRM2 | 7138 |
| NPY | 7117 |
| GNA15 | 7063 |
| POMC | 7031 |
| OPRK1 | 7013 |
| PPP2R1B | 6984 |
| RGSL1 | 6974 |
| RGS13 | 6923 |
| PENK | 6920 |
| PPP1R1B | 6847 |
| CCR10 | 6837 |
| CXCL12 | 6660 |
| GNB1 | 6594 |
| RGS1 | 6587 |
| CCR4 | 6538 |
| CAMK2A | 6475 |
| ADCY5 | 6465 |
| PLA2G4A | 6436 |
| RGS8 | 6416 |
| P2RY14 | 6278 |
| NMUR2 | 6200 |
| CCL25 | 6175 |
| PDE1B | 6142 |
| GNAI1 | 6083 |
| TAS2R19 | 5911 |
| GPER1 | 5884 |
| DRD3 | 5795 |
| CCR9 | 5762 |
| MCHR2 | 5743 |
| RXFP3 | 5733 |
| CCL28 | 5611 |
| GNAT1 | 5605 |
| CXCL5 | 5599 |
| PDE4C | 5598 |
| MTNR1A | 5586 |
| RHO | 5540 |
| OXER1 | 5454 |
| NMS | 5283 |
| OXGR1 | 5190 |
| NPY5R | 5059 |
| PLCB1 | 4905 |
| SSTR2 | 4630 |
| CCR7 | 4543 |
| RLN3 | 4541 |
| CREB1 | 4535 |
| INSL5 | 4503 |
| ADRA2B | 4418 |
| CALM1 | 4408 |
| PPP3R1 | 4405 |
| GNG2 | 4394 |
| GNG13 | 4355 |
| GRM3 | 4344 |
| RGS10 | 4249 |
| PRKAR2B | 4163 |
| CAMK2B | 4138 |
| C5 | 3928 |
| PMCH | 3902 |
| SUCNR1 | 3878 |
| GALR2 | 3874 |
| GNAT3 | 3829 |
| GRM6 | 3825 |
| GRM4 | 3717 |
| PRKCA | 3665 |
| PLCB3 | 3506 |
| S1PR3 | 3488 |
| ADCY6 | 3433 |
| PTGER3 | 3410 |
| CCR3 | 3198 |
| ADCY9 | 3186 |
| CXCL9 | 3013 |
| PNOC | 2919 |
| PLCB4 | 2798 |
| TAS1R1 | 2741 |
| CAMKK2 | 2708 |
| HTR5A | 2702 |
| TAS2R30 | 2592 |
| PPP3CA | 2590 |
| TAS2R40 | 2447 |
| RGR | 2349 |
| RGS7 | 2275 |
| GNG11 | 2196 |
| GPSM1 | 2159 |
| ADCY8 | 1989 |
| OPRD1 | 1938 |
| HTR1D | 1919 |
| RGS12 | 1889 |
| CCL27 | 1818 |
| ITPR3 | 1792 |
| TAS2R1 | 1759 |
| CXCR2 | 1512 |
| RGS20 | 1499 |
| TAS2R38 | 1397 |
| ADCY4 | 1319 |
| HTR1F | 1259 |
| GAL | 1250 |
| NMUR1 | 1206 |
| HCAR2 | 1147 |
| PDE4B | 1061 |
| RGS14 | 1007 |
| ADCY7 | 992 |
| ADCY1 | 877 |
| PDE4D | 866 |
| CXCL10 | 840 |
| RGS22 | 707 |
| GABBR2 | 677 |
| APLNR | 419 |
| LPAR2 | 380 |
| S1PR4 | 364 |
| PDYN | 352 |
| PDE1A | 346 |
| GABBR1 | 239 |
| GNAL | 162 |
| PSAP | 108 |
| CXCL8 | 1 |
| GPR17 | -95 |
| ADCY2 | -102 |
| GNGT1 | -114 |
| GNB3 | -122 |
| CXCL6 | -155 |
| GRM8 | -198 |
| OPN3 | -217 |
| BDKRB2 | -293 |
| CXCR4 | -294 |
| RRH | -371 |
| GNG5 | -594 |
| PDE1C | -896 |
| ITPR1 | -933 |
| TAS2R46 | -936 |
| TAS2R20 | -1014 |
| GPR37 | -1067 |
| GNG12 | -1102 |
| TAS2R7 | -1322 |
| CASR | -1411 |
| NBEA | -1471 |
| KPNA2 | -1606 |
| GNG10 | -1690 |
| ITPR2 | -1996 |
| TAS1R3 | -2021 |
| GNA14 | -2118 |
| CX3CR1 | -2125 |
| ADORA3 | -2510 |
| PPP2CB | -2525 |
| CDK5 | -2619 |
| CAMK2D | -2651 |
| RGS3 | -2742 |
| TAS2R13 | -2746 |
| C5AR1 | -2800 |
| OPRL1 | -2816 |
| GNAI3 | -2862 |
| PPP2R1A | -2973 |
| RGS19 | -3035 |
| TAS2R43 | -3090 |
| GPSM2 | -3325 |
| ADORA1 | -3347 |
| OPN5 | -3381 |
| CAMK2G | -3421 |
| RGS5 | -3469 |
| PPP3CB | -3495 |
| GPSM3 | -3497 |
| ADCY3 | -3624 |
| CCL19 | -3829 |
| RGS6 | -3844 |
| MTNR1B | -3861 |
| NMU | -3969 |
| SRC | -4047 |
| PRKACG | -4062 |
| GRM7 | -4083 |
| RGS16 | -4097 |
| GNA11 | -4159 |
| PRKAR1B | -4290 |
| PRKCD | -4339 |
| P2RY12 | -4362 |
| PDE4A | -4412 |
| NPBWR1 | -4420 |
| CCR5 | -4441 |
| NPB | -4452 |
| RGS4 | -4600 |
| TAS2R39 | -4617 |
| FPR2 | -4671 |
| GNG3 | -4759 |
| DRD4 | -4824 |
| NPW | -4860 |
| CXCL2 | -4895 |
| PYY | -4900 |
| CXCL16 | -5103 |
| FPR1 | -5112 |
| GPR55 | -5124 |
| RXFP4 | -5260 |
| GPR37L1 | -5302 |
| TAS1R2 | -5365 |
| GNG4 | -5388 |
| PRKACA | -5493 |
| PPP3CC | -5608 |
| CAMK4 | -5681 |
| PRKCG | -5710 |
| APP | -5711 |
| PRKACB | -5745 |
| GNAQ | -5998 |
| MAPK1 | -6079 |
| KNG1 | -6316 |
| PLCB2 | -6460 |
| GNAS | -6556 |
| CHRM2 | -7066 |
| S1PR5 | -7083 |
| LPAR3 | -7203 |
| PRKAR1A | -7361 |
| RGS17 | -7394 |
| P2RY13 | -7438 |
| SSTR5 | -7613 |
| GNB4 | -7626 |
| AHCYL1 | -7708 |
| TAS2R42 | -8167 |
| TAS2R41 | -8174 |
| CXCL3 | -8299 |
| CORT | -8356 |
| TAS2R3 | -8359 |
| HEBP1 | -8411 |
| TAS2R31 | -8433 |
| CNR2 | -8482 |
| TAS2R16 | -8745 |
| GNB2 | -8837 |
| GNB5 | -8860 |
| PCP2 | -8983 |
| GNG7 | -9020 |
| PPY | -9221 |
| TAS2R10 | -9301 |
| PPP2CA | -9312 |
| GALR3 | -9447 |
| PPP2R5D | -9565 |
| OPN1SW | -9689 |
| RGS9 | -9693 |
| GRK2 | -9768 |
| CAMKK1 | -9782 |
| GNG8 | -9902 |
| PRKAR2A | -9917 |
| NPBWR2 | -10033 |
| CCR8 | -10260 |
| RGS18 | -10526 |
| S1PR2 | -10717 |
| TAS2R4 | -10725 |
| CXCL11 | -10904 |
| TAS2R14 | -10916 |
| AGT | -11085 |
| MCHR1 | -11205 |
| SSTR3 | -11225 |
| HRH4 | -11329 |
| TAS2R60 | -11412 |
| CX3CL1 | -11454 |
| ANXA1 | -11455 |
REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS
| 601 | |
|---|---|
| set | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS |
| setSize | 188 |
| pANOVA | 9.22e-05 |
| s.dist | 0.165 |
| p.adjustANOVA | 0.0252 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CCL22 | 10065 |
| SAA1 | 10054 |
| CCL4 | 10026 |
| CCL5 | 10003 |
| CXCR6 | 9994 |
| CXCL1 | 9982 |
| CCR2 | 9938 |
| CCR6 | 9905 |
| CXCR5 | 9845 |
| SSTR4 | 9810 |
| CCL13 | 9779 |
| CCL1 | 9680 |
| TRHR | 9561 |
| CCRL2 | 9506 |
| C3AR1 | 9470 |
| FPR3 | 9433 |
| PPBP | 9375 |
| SSTR1 | 9359 |
| ACKR3 | 9342 |
| CCL16 | 9292 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CCL22 | 10065 |
| SAA1 | 10054 |
| CCL4 | 10026 |
| CCL5 | 10003 |
| CXCR6 | 9994 |
| CXCL1 | 9982 |
| CCR2 | 9938 |
| CCR6 | 9905 |
| CXCR5 | 9845 |
| SSTR4 | 9810 |
| CCL13 | 9779 |
| CCL1 | 9680 |
| TRHR | 9561 |
| CCRL2 | 9506 |
| C3AR1 | 9470 |
| FPR3 | 9433 |
| PPBP | 9375 |
| SSTR1 | 9359 |
| ACKR3 | 9342 |
| CCL16 | 9292 |
| CCL20 | 9053 |
| CXCR1 | 8889 |
| NTSR1 | 8849 |
| C3 | 8800 |
| EDN2 | 8784 |
| CCL7 | 8746 |
| MC3R | 8676 |
| CCL23 | 8588 |
| BDKRB1 | 8451 |
| CCL21 | 8262 |
| PRLH | 8256 |
| NPY2R | 8212 |
| MLNR | 8089 |
| SST | 8074 |
| TACR3 | 8070 |
| GALR1 | 8027 |
| CCK | 7953 |
| CCR1 | 7916 |
| PF4 | 7738 |
| RXFP1 | 7693 |
| AVPR1B | 7655 |
| F2R | 7565 |
| NPFFR2 | 7469 |
| CXCL13 | 7397 |
| OPRM1 | 7376 |
| NPY1R | 7272 |
| ACKR1 | 7270 |
| UTS2 | 7196 |
| NPY | 7117 |
| NPS | 7072 |
| POMC | 7031 |
| PROKR1 | 7028 |
| OPRK1 | 7013 |
| PENK | 6920 |
| CCR10 | 6837 |
| NMBR | 6781 |
| CXCL12 | 6660 |
| RXFP2 | 6654 |
| CCR4 | 6538 |
| KISS1R | 6441 |
| NMUR2 | 6200 |
| CCL25 | 6175 |
| HCRT | 6111 |
| GPER1 | 5884 |
| CCR9 | 5762 |
| MCHR2 | 5743 |
| RXFP3 | 5733 |
| CCL28 | 5611 |
| CXCL5 | 5599 |
| NMS | 5283 |
| NPY5R | 5059 |
| NTSR2 | 5041 |
| EDNRA | 4813 |
| GRP | 4754 |
| F2RL1 | 4731 |
| SSTR2 | 4630 |
| NLN | 4563 |
| CCR7 | 4543 |
| RLN3 | 4541 |
| INSL5 | 4503 |
| CCL17 | 4204 |
| EDNRB | 4156 |
| C5 | 3928 |
| PMCH | 3902 |
| GALR2 | 3874 |
| TAC1 | 3845 |
| XCL1 | 3619 |
| PRLHR | 3347 |
| CCR3 | 3198 |
| CXCL9 | 3013 |
| PNOC | 2919 |
| F2 | 2752 |
| GHRL | 2350 |
| MC2R | 2199 |
| OPRD1 | 1938 |
| CCL27 | 1818 |
| NPSR1 | 1687 |
| CXCR2 | 1512 |
| CCKAR | 1420 |
| GAL | 1250 |
| NMUR1 | 1206 |
| CXCL10 | 840 |
| TRH | 767 |
| QRFP | 726 |
| APLNR | 419 |
| MC5R | 388 |
| PDYN | 352 |
| PSAP | 108 |
| CXCL8 | 1 |
| CXCL6 | -155 |
| HCRTR1 | -268 |
| BDKRB2 | -293 |
| CXCR4 | -294 |
| OXTR | -380 |
| KEL | -403 |
| NMB | -786 |
| GPR37 | -1067 |
| XCR1 | -1413 |
| XCL2 | -1654 |
| CX3CR1 | -2125 |
| AVPR1A | -2336 |
| PROK1 | -2566 |
| C5AR1 | -2800 |
| OPRL1 | -2816 |
| CCKBR | -2845 |
| ECE1 | -2935 |
| HCRTR2 | -2995 |
| CCL2 | -3077 |
| PROK2 | -3326 |
| UTS2R | -3473 |
| GHSR | -3477 |
| NPFFR1 | -3632 |
| MC1R | -3657 |
| NPFF | -3793 |
| CCL19 | -3829 |
| NMU | -3969 |
| EDN3 | -3991 |
| NPBWR1 | -4420 |
| CCR5 | -4441 |
| NPB | -4452 |
| FPR2 | -4671 |
| AGTR1 | -4681 |
| NPW | -4860 |
| CXCL2 | -4895 |
| PYY | -4900 |
| CXCL16 | -5103 |
| FPR1 | -5112 |
| RXFP4 | -5260 |
| GPR37L1 | -5302 |
| APP | -5711 |
| KNG1 | -6316 |
| EDN1 | -6433 |
| NTS | -6474 |
| MLN | -6577 |
| TACR1 | -6605 |
| SSTR5 | -7613 |
| TACR2 | -7849 |
| RLN2 | -8288 |
| CXCL3 | -8299 |
| CORT | -8356 |
| HEBP1 | -8411 |
| ECE2 | -8809 |
| UTS2B | -9001 |
| INSL3 | -9149 |
| PPY | -9221 |
| KISS1 | -9276 |
| OXT | -9288 |
| CCL11 | -9384 |
| GALR3 | -9447 |
| F2RL2 | -9581 |
| PROKR2 | -9728 |
| F2RL3 | -9874 |
| NPBWR2 | -10033 |
| ACKR2 | -10236 |
| CCR8 | -10260 |
| QRFPR | -10577 |
| MC4R | -10716 |
| C5AR2 | -10895 |
| CXCL11 | -10904 |
| TAC3 | -10924 |
| AGT | -11085 |
| CCL3 | -11116 |
| MCHR1 | -11205 |
| SSTR3 | -11225 |
| AVP | -11350 |
| CX3CL1 | -11454 |
| ANXA1 | -11455 |
| ACKR4 | -11776 |
REACTOME_SENSORY_PERCEPTION
| 1581 | |
|---|---|
| set | REACTOME_SENSORY_PERCEPTION |
| setSize | 555 |
| pANOVA | 0.000215 |
| s.dist | 0.0919 |
| p.adjustANOVA | 0.048 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| OR6C4 | 10137 |
| OR6C65 | 10050 |
| OR7A10 | 10048 |
| OR2F2 | 10039 |
| OR10S1 | 10038 |
| OR2T3 | 10015 |
| OR1L4 | 9989 |
| OR1S2 | 9952 |
| TAS2R8 | 9890 |
| OR5AK2 | 9881 |
| OR5K3 | 9872 |
| OR4X2 | 9855 |
| OR5AR1 | 9842 |
| OR10A7 | 9835 |
| OR1N1 | 9834 |
| OR1E2 | 9833 |
| OR2T33 | 9828 |
| OR3A3 | 9825 |
| OR8G5 | 9817 |
| OR2AK2 | 9807 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| OR6C4 | 10137.0 |
| OR6C65 | 10050.0 |
| OR7A10 | 10048.0 |
| OR2F2 | 10039.0 |
| OR10S1 | 10038.0 |
| OR2T3 | 10015.0 |
| OR1L4 | 9989.0 |
| OR1S2 | 9952.0 |
| TAS2R8 | 9890.0 |
| OR5AK2 | 9881.0 |
| OR5K3 | 9872.0 |
| OR4X2 | 9855.0 |
| OR5AR1 | 9842.0 |
| OR10A7 | 9835.0 |
| OR1N1 | 9834.0 |
| OR1E2 | 9833.0 |
| OR2T33 | 9828.0 |
| OR3A3 | 9825.0 |
| OR8G5 | 9817.0 |
| OR2AK2 | 9807.0 |
| OR56A4 | 9805.0 |
| OR6A2 | 9780.0 |
| OR52H1 | 9739.0 |
| OR10T2 | 9734.0 |
| OR2AG2 | 9728.0 |
| OR5AU1 | 9721.0 |
| OR4X1 | 9708.0 |
| OR2V1 | 9698.0 |
| OR6Y1 | 9694.0 |
| OR6F1 | 9672.0 |
| OR56B4 | 9657.0 |
| OR1M1 | 9652.0 |
| OR52E6 | 9632.0 |
| OR10W1 | 9607.0 |
| RTP2 | 9594.0 |
| OR8B8 | 9589.0 |
| OR2M2 | 9588.0 |
| OR10G2 | 9582.0 |
| RLBP1 | 9565.0 |
| OR1E1 | 9540.0 |
| KCNMB1 | 9518.0 |
| OR2T12 | 9511.0 |
| OR6K3 | 9510.0 |
| CNGA4 | 9503.0 |
| OR2L3 | 9497.0 |
| OR4D9 | 9491.0 |
| OR51E1 | 9482.0 |
| OR6C74 | 9477.0 |
| OR5K4 | 9453.0 |
| OR52L1 | 9440.0 |
| OR51G2 | 9421.0 |
| TAS2R5 | 9406.0 |
| OR5K2 | 9395.0 |
| OR14I1 | 9368.0 |
| OR5H2 | 9358.0 |
| OR8G1 | 9351.0 |
| OR10X1 | 9337.0 |
| OR2AT4 | 9328.0 |
| OR8U3 | 9322.0 |
| OR2AP1 | 9307.0 |
| OTOP1 | 9231.0 |
| OR1K1 | 9230.0 |
| OR2G6 | 9196.0 |
| OR6Q1 | 9187.0 |
| OR9K2 | 9150.0 |
| OR10V1 | 9127.0 |
| OR8S1 | 9118.0 |
| OR4M1 | 9093.0 |
| OR4B1 | 9070.0 |
| OR5T2 | 9069.0 |
| OR6C3 | 9044.0 |
| OR5V1 | 9035.0 |
| OR4K13 | 9030.0 |
| OR8D4 | 8988.0 |
| OR1J4 | 8982.0 |
| OR13D1 | 8979.0 |
| OR7G2 | 8966.0 |
| FSCN2 | 8965.0 |
| OR11H6 | 8930.0 |
| OR7A17 | 8923.0 |
| MYO7A | 8917.0 |
| TTR | 8913.0 |
| OR10Q1 | 8883.0 |
| USH1G | 8874.0 |
| OR9I1 | 8873.0 |
| OR5M3 | 8813.0 |
| OR2T11 | 8805.0 |
| OR10Z1 | 8794.0 |
| OR5L2 | 8768.0 |
| OR4C16 | 8762.0 |
| AKR1C4 | 8761.0 |
| OR4D6 | 8711.0 |
| OR2F1 | 8709.0 |
| OR1A2 | 8672.0 |
| OR51Q1 | 8642.0 |
| OR7G3 | 8637.0 |
| RTP1 | 8621.0 |
| OR5AN1 | 8616.0 |
| OR2T4 | 8592.0 |
| OR4C45 | 8571.0 |
| OR1B1 | 8515.0 |
| GRM1 | 8496.0 |
| OR10J3 | 8493.0 |
| OR10G9 | 8488.0 |
| OR52N1 | 8467.0 |
| OR6C2 | 8448.0 |
| OR2T6 | 8378.0 |
| RBP1 | 8276.0 |
| OR6C1 | 8239.0 |
| OR9A4 | 8200.0 |
| CACNA2D2 | 8178.0 |
| RDH16 | 8169.0 |
| OR2T8 | 8142.0 |
| OR1L1 | 8039.0 |
| OR51B2 | 8032.0 |
| OR5F1 | 7993.0 |
| HSD17B1 | 7974.0 |
| OR52B2 | 7964.0 |
| USH1C | 7939.0 |
| APOA4 | 7936.0 |
| APOB | 7935.0 |
| RBP2 | 7928.0 |
| OR51T1 | 7899.0 |
| CHRNA10 | 7876.0 |
| LRAT | 7864.0 |
| OR1C1 | 7824.0 |
| CTBP2 | 7726.0 |
| OR51S1 | 7704.0 |
| OR2L13 | 7644.0 |
| OR6C6 | 7637.0 |
| KCNJ2 | 7604.0 |
| RBP4 | 7600.0 |
| OR6C75 | 7582.0 |
| TAS2R50 | 7568.0 |
| RPE65 | 7554.0 |
| KCNMA1 | 7468.0 |
| OR6N1 | 7400.0 |
| OR6P1 | 7380.0 |
| OR2J2 | 7378.0 |
| GRXCR2 | 7352.0 |
| OR10C1 | 7269.0 |
| OR2AG1 | 7257.0 |
| OR2B2 | 7255.0 |
| LHFPL5 | 7160.0 |
| OR52D1 | 7145.0 |
| OR7C2 | 7012.0 |
| OR2L2 | 6846.0 |
| OR5D18 | 6809.0 |
| SCN3A | 6787.0 |
| OR51L1 | 6604.0 |
| OR51A2 | 6599.0 |
| GNB1 | 6594.0 |
| REEP1 | 6540.0 |
| OR14J1 | 6472.0 |
| KCNN2 | 6462.0 |
| OR51I1 | 6459.0 |
| OR51E2 | 6411.0 |
| OR10H2 | 6405.0 |
| OR5D13 | 6398.0 |
| OR4C46 | 6395.0 |
| OR2H2 | 6322.0 |
| OR5D16 | 6294.0 |
| OR5B17 | 6201.0 |
| OR13C8 | 6125.0 |
| OR2T27 | 6075.0 |
| OR2K2 | 6052.0 |
| ACTB | 6012.0 |
| GPIHBP1 | 5959.0 |
| OR51V1 | 5947.0 |
| OR6S1 | 5930.0 |
| RETSAT | 5887.0 |
| SCN9A | 5855.0 |
| SAG | 5826.0 |
| MYH9 | 5790.0 |
| OR13C9 | 5700.0 |
| GNAT1 | 5605.0 |
| RHO | 5540.0 |
| RDX | 5529.0 |
| OR2L8 | 5442.0 |
| LRP2 | 5409.0 |
| AGRN | 5376.0 |
| OR13A1 | 5302.0 |
| ESPNL | 5296.0 |
| STRC | 5224.0 |
| GUCA1A | 5219.0 |
| OR10J5 | 5126.0 |
| CACNA1D | 5116.0 |
| OR2B11 | 5029.0 |
| OR2M5 | 4992.0 |
| HSPG2 | 4822.0 |
| OR2S2 | 4749.0 |
| PDE6B | 4746.0 |
| CNGB1 | 4738.0 |
| TMIE | 4703.0 |
| PLS1 | 4697.0 |
| LDB1 | 4442.0 |
| CALM1 | 4408.0 |
| GNG13 | 4355.0 |
| TMC1 | 4320.0 |
| SDC1 | 4312.0 |
| OR52W1 | 4230.0 |
| PLB1 | 4218.0 |
| OR11L1 | 4149.0 |
| OR4N5 | 4139.0 |
| GRK7 | 4124.0 |
| EPB41L3 | 3941.0 |
| MYO15A | 3931.0 |
| OR2A2 | 3838.0 |
| GNAT3 | 3829.0 |
| OR8B2 | 3812.0 |
| FNTB | 3778.0 |
| GRM4 | 3717.0 |
| DNAJC5 | 3699.0 |
| PRKCA | 3665.0 |
| NMT1 | 3616.0 |
| LPL | 3592.0 |
| OR4A16 | 3568.0 |
| GRK1 | 3512.0 |
| OR7D4 | 3435.0 |
| OR56A3 | 3399.0 |
| OR5M10 | 3384.0 |
| SDC2 | 3351.0 |
| OR51A7 | 3330.0 |
| OTOGL | 3287.0 |
| RIPOR2 | 3180.0 |
| ABCA4 | 3168.0 |
| SLC26A5 | 3104.0 |
| LRP8 | 3063.0 |
| OR5C1 | 3009.0 |
| APOC3 | 2952.0 |
| OR4K2 | 2900.0 |
| ATP2B2 | 2817.0 |
| ANO2 | 2765.0 |
| OR11G2 | 2756.0 |
| TAS1R1 | 2741.0 |
| OR3A1 | 2734.0 |
| OR10H4 | 2725.0 |
| GUCA1B | 2724.0 |
| OR7D2 | 2706.0 |
| TAS2R30 | 2592.0 |
| METAP1 | 2523.0 |
| OR52B6 | 2522.0 |
| OR8I2 | 2472.0 |
| TAS2R40 | 2447.0 |
| OR6C70 | 2414.0 |
| LRP1 | 2411.0 |
| OR2H1 | 2391.0 |
| OR10H3 | 2371.0 |
| EBF1 | 2363.0 |
| OR5T3 | 2361.0 |
| DHRS3 | 2352.0 |
| OR2Z1 | 2271.0 |
| CNGA1 | 2260.0 |
| CLIC5 | 2096.0 |
| GUCY2D | 2067.0 |
| RDH10 | 2054.0 |
| CACNB2 | 1978.0 |
| MYO1C | 1935.0 |
| CIB2 | 1799.0 |
| ITPR3 | 1792.0 |
| TAS2R1 | 1759.0 |
| EPS8 | 1671.0 |
| GSN | 1576.0 |
| ATP2B1 | 1500.0 |
| SLC24A1 | 1489.0 |
| TAS2R38 | 1397.0 |
| SPTBN1 | 1334.0 |
| MYO3B | 1322.0 |
| OR5H6 | 1226.0 |
| CYP4V2 | 1185.0 |
| OR51B6 | 1136.0 |
| RDH12 | 1113.0 |
| OR7C1 | 1083.0 |
| OR9Q2 | 958.0 |
| RBP3 | 945.0 |
| SCNN1B | 824.0 |
| SLC17A8 | 705.0 |
| LDLR | 643.0 |
| OR1F1 | 566.0 |
| BCO1 | 522.0 |
| OR8K3 | 462.0 |
| OR1S1 | 452.0 |
| OR2T1 | 319.0 |
| OR1L3 | 224.0 |
| OR4K14 | 196.0 |
| SCN4B | 175.0 |
| GNAL | 162.0 |
| RGS9BP | 155.0 |
| GPC1 | 121.0 |
| OR52E4 | 104.0 |
| LHX2 | 93.0 |
| PRKCQ | 41.0 |
| OR8J3 | -19.0 |
| CALHM1 | -25.0 |
| GNGT1 | -114.0 |
| GNB3 | -122.0 |
| AKR1C1 | -137.0 |
| OR5D14 | -138.0 |
| OR2W1 | -205.0 |
| TRPM5 | -211.0 |
| OR6T1 | -313.0 |
| OR52I1 | -355.0 |
| OR5H15 | -436.0 |
| GUCA1C | -479.0 |
| OR2Y1 | -566.0 |
| OR12D3 | -764.0 |
| PCLO | -799.0 |
| OR5P2 | -916.0 |
| TAS2R46 | -936.0 |
| SCN2B | -949.0 |
| TAS2R20 | -1014.0 |
| SCN1B | -1017.0 |
| CAPZB | -1025.0 |
| OR5M1 | -1128.0 |
| XIRP2 | -1265.0 |
| GPC6 | -1319.0 |
| TAS2R7 | -1322.0 |
| GRXCR1 | -1589.0 |
| OTOF | -1592.0 |
| OR5K1 | -1724.0 |
| OR5A1 | -1741.0 |
| OR2G3 | -1754.0 |
| CHRNA9 | -1776.0 |
| OR11H4 | -1808.0 |
| OR52I2 | -1814.0 |
| DHRS9 | -1819.0 |
| BSN | -1848.0 |
| OR51B5 | -1927.0 |
| OR5L1 | -1934.0 |
| OR4D2 | -1986.0 |
| OR14C36 | -1992.0 |
| OR4K5 | -1995.0 |
| TAS1R3 | -2021.0 |
| OR2M3 | -2026.0 |
| OR6K2 | -2108.0 |
| AKR1C3 | -2123.0 |
| OR8D2 | -2210.0 |
| OR6C76 | -2259.0 |
| HSD17B6 | -2306.0 |
| CDH23 | -2326.0 |
| OR2M4 | -2349.0 |
| ACTG1 | -2359.0 |
| APOC2 | -2394.0 |
| OR4D10 | -2430.0 |
| PCDH15 | -2444.0 |
| LRP12 | -2514.0 |
| EZR | -2528.0 |
| CAPZA1 | -2585.0 |
| OR4D5 | -2597.0 |
| OR9Q1 | -2718.0 |
| OR1J2 | -2720.0 |
| TAS2R13 | -2746.0 |
| OR14A16 | -2759.0 |
| RDH11 | -2763.0 |
| NMT2 | -2770.0 |
| OR5M8 | -2897.0 |
| OR8D1 | -2968.0 |
| TAS2R43 | -3090.0 |
| OR10A5 | -3101.0 |
| RDH5 | -3108.0 |
| OR2D2 | -3215.0 |
| OR8H3 | -3413.0 |
| OR8K5 | -3428.0 |
| OR5T1 | -3492.0 |
| KCNQ4 | -3498.0 |
| LRRC52 | -3514.0 |
| OR4L1 | -3556.0 |
| ADCY3 | -3624.0 |
| OR10A2 | -3644.0 |
| SCNN1G | -3722.0 |
| OR52R1 | -3941.0 |
| STX1A | -3943.0 |
| OR3A2 | -4146.0 |
| EPB41L1 | -4198.0 |
| OR4K17 | -4266.0 |
| MYO3A | -4280.0 |
| METAP2 | -4526.0 |
| TAS2R39 | -4617.0 |
| PDE6G | -4832.0 |
| OR52E8 | -4925.0 |
| OR6B3 | -4983.0 |
| CAMKMT | -4984.0 |
| TRPM4 | -5081.0 |
| OR6K6 | -5095.0 |
| OR4A5 | -5136.0 |
| SPTAN1 | -5203.0 |
| OR10G7 | -5216.0 |
| GRK4 | -5270.0 |
| TAS1R2 | -5365.0 |
| OR1D2 | -5492.0 |
| OR4F6 | -5516.0 |
| EPS8L2 | -5524.0 |
| VAMP2 | -5566.0 |
| OR6C68 | -5568.0 |
| OR4N2 | -5615.0 |
| OR1L8 | -5692.0 |
| OR7E24 | -5722.0 |
| GPC5 | -5754.0 |
| TWF1 | -5822.0 |
| OR1A1 | -5832.0 |
| OR12D2 | -5887.0 |
| OR2B6 | -5931.0 |
| CABP1 | -6008.0 |
| SCN2A | -6016.0 |
| OR4F15 | -6018.0 |
| LRP10 | -6071.0 |
| WHRN | -6171.0 |
| OR1J1 | -6238.0 |
| SNAP25 | -6279.0 |
| OR6M1 | -6341.0 |
| OR13C3 | -6353.0 |
| PLCB2 | -6460.0 |
| PDE6A | -6462.0 |
| OR52K1 | -6465.0 |
| OR4A15 | -6601.0 |
| ESPN | -6633.0 |
| OR6B1 | -6643.0 |
| BCO2 | -6682.0 |
| OR5I1 | -6712.0 |
| OR1I1 | -6716.0 |
| OR52J3 | -6790.0 |
| OR13C2 | -6793.0 |
| SCNN1A | -6794.0 |
| SDC3 | -6847.0 |
| OR10G4 | -6858.0 |
| OR5B12 | -7105.0 |
| OR4C6 | -7193.0 |
| PNLIP | -7298.0 |
| OR52M1 | -7351.0 |
| NAPEPLD | -7372.0 |
| RCVRN | -7419.0 |
| PJVK | -7424.0 |
| OTOG | -7448.0 |
| OR4D1 | -7473.0 |
| OR51F1 | -7494.0 |
| OR9A2 | -7528.0 |
| OR10K1 | -7538.0 |
| OR1N2 | -7572.0 |
| OR10H5 | -7665.0 |
| OR5B21 | -7709.0 |
| OR5W2 | -7896.0 |
| OR56A1 | -7913.0 |
| FNTA | -7917.0 |
| APOM | -8069.0 |
| CABP2 | -8083.0 |
| TRIOBP | -8113.0 |
| TAS2R41 | -8174.0 |
| OR9G4 | -8215.0 |
| OR5AC2 | -8291.0 |
| OR6X1 | -8310.0 |
| CALHM3 | -8318.0 |
| OR2AE1 | -8353.0 |
| TAS2R3 | -8359.0 |
| TAS2R31 | -8433.0 |
| OR8U1 | -8445.0 |
| APOA2 | -8526.0 |
| OR8U8 | -8614.0 |
| OR10A4 | -8624.0 |
| RAB3A | -8649.0 |
| TPRN | -8729.0 |
| TAS2R16 | -8745.0 |
| OR2A5 | -8777.0 |
| GNB5 | -8860.0 |
| OR5AS1 | -8865.0 |
| APOA1 | -8926.0 |
| OR10G3 | -8945.0 |
| OR13G1 | -8950.0 |
| OR10AD1 | -8965.0 |
| OR6N2 | -9041.0 |
| SDC4 | -9101.0 |
| OR4C15 | -9121.0 |
| SCNN1D | -9132.0 |
| OR8K1 | -9146.0 |
| OR52A1 | -9236.0 |
| TAS2R10 | -9301.0 |
| OR2D3 | -9318.0 |
| OR2L5 | -9329.0 |
| OR1L6 | -9414.0 |
| OR51I2 | -9442.0 |
| OR1G1 | -9451.0 |
| OR5B3 | -9550.0 |
| TWF2 | -9563.0 |
| OR52K2 | -9596.0 |
| OR10J1 | -9602.0 |
| OR2C3 | -9641.0 |
| OR10A3 | -9687.0 |
| OPN1SW | -9689.0 |
| RGS9 | -9693.0 |
| OR7A5 | -9724.0 |
| OR51G1 | -9742.0 |
| OR6B2 | -9797.0 |
| OR4S1 | -9864.0 |
| OR10AG1 | -9883.0 |
| OR5P3 | -10015.0 |
| OR51F2 | -10059.0 |
| RDH8 | -10072.0 |
| OR8B12 | -10078.0 |
| OR8J1 | -10117.0 |
| OR52A5 | -10160.0 |
| OR1Q1 | -10161.0 |
| TMC2 | -10171.0 |
| OR2A14 | -10206.0 |
| OR56A5 | -10211.0 |
| OR4C12 | -10242.0 |
| GPC2 | -10327.0 |
| OR56B1 | -10342.0 |
| OR4K1 | -10352.0 |
| OR51M1 | -10377.0 |
| CLPS | -10426.0 |
| STRA6 | -10450.0 |
| OR4K15 | -10527.0 |
| OR4C3 | -10548.0 |
| OR2B3 | -10559.0 |
| OR2C1 | -10598.0 |
| OR10P1 | -10606.0 |
| OR52E2 | -10639.0 |
| OR51B4 | -10702.0 |
| OR13F1 | -10711.0 |
| TAS2R4 | -10725.0 |
| CAPZA2 | -10797.0 |
| OR2W3 | -10852.0 |
| OR11A1 | -10872.0 |
| TAS2R14 | -10916.0 |
| OR4E2 | -10997.0 |
| OR5B2 | -11054.0 |
| OR5J2 | -11058.0 |
| OR51D1 | -11098.0 |
| OR10G8 | -11102.0 |
| OR2G2 | -11146.0 |
| AKR1B10 | -11151.0 |
| OR13J1 | -11186.0 |
| OR10H1 | -11188.0 |
| OR10K2 | -11204.0 |
| OR5AP2 | -11227.0 |
| OR8H1 | -11248.0 |
| SDR9C7 | -11253.0 |
| APOE | -11264.0 |
| OR5M11 | -11294.0 |
| OR6V1 | -11296.0 |
| OR10A6 | -11308.0 |
| OR52N2 | -11328.0 |
| OR8B4 | -11334.0 |
| OR5M9 | -11358.0 |
| OR9G1 | -11436.5 |
| OR9G9 | -11436.5 |
| OR2V2 | -11525.0 |
| OR4A47 | -11570.0 |
| OR13C4 | -11592.0 |
| OR2A12 | -11629.0 |
| OR8A1 | -11634.0 |
| OR5A2 | -11666.0 |
| OR7G1 | -11749.0 |
| OR4D11 | -11786.0 |
| OR5H1 | -11819.0 |
| OR2M7 | -11826.0 |
REACTOME_NEUTROPHIL_DEGRANULATION
| 1053 | |
|---|---|
| set | REACTOME_NEUTROPHIL_DEGRANULATION |
| setSize | 460 |
| pANOVA | 0.000234 |
| s.dist | -0.1 |
| p.adjustANOVA | 0.048 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| AZU1 | -11805 |
| FOLR3 | -11766 |
| SIGLEC5 | -11615 |
| FCGR3B | -11603 |
| STING1 | -11581 |
| MPO | -11563 |
| S100A8 | -11505 |
| RNASE3 | -11488 |
| TARM1 | -11477 |
| CEACAM1 | -11458 |
| CEACAM3 | -11421 |
| CD300A | -11418 |
| HP | -11299 |
| LRG1 | -11267 |
| NME2 | -11252 |
| DOK3 | -11187 |
| ELANE | -11131 |
| CTSG | -11118 |
| TYROBP | -11079 |
| ADA2 | -11052 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| AZU1 | -11805 |
| FOLR3 | -11766 |
| SIGLEC5 | -11615 |
| FCGR3B | -11603 |
| STING1 | -11581 |
| MPO | -11563 |
| S100A8 | -11505 |
| RNASE3 | -11488 |
| TARM1 | -11477 |
| CEACAM1 | -11458 |
| CEACAM3 | -11421 |
| CD300A | -11418 |
| HP | -11299 |
| LRG1 | -11267 |
| NME2 | -11252 |
| DOK3 | -11187 |
| ELANE | -11131 |
| CTSG | -11118 |
| TYROBP | -11079 |
| ADA2 | -11052 |
| TNFAIP6 | -11016 |
| BRI3 | -10960 |
| GLIPR1 | -10945 |
| EPX | -10937 |
| GHDC | -10913 |
| S100A9 | -10869 |
| DSG1 | -10854 |
| S100A7 | -10851 |
| MNDA | -10700 |
| LYZ | -10667 |
| AGPAT2 | -10653 |
| PLAU | -10533 |
| FGR | -10528 |
| MLEC | -10442 |
| MS4A3 | -10389 |
| P2RX1 | -10381 |
| VAT1 | -10378 |
| COMMD3 | -10370 |
| ORMDL3 | -10326 |
| ALDH3B1 | -10213 |
| PSMA5 | -10194 |
| SIRPB1 | -10186 |
| SELL | -10157 |
| GSTP1 | -10150 |
| DYNLL1 | -10134 |
| LAMTOR3 | -10113 |
| CYB5R3 | -10081 |
| TSPAN14 | -10027 |
| LAMTOR2 | -10010 |
| TUBB | -9940 |
| GGH | -9921 |
| ALAD | -9849 |
| VCL | -9835 |
| BIN2 | -9807 |
| RAP1B | -9640 |
| CTSD | -9587 |
| CHRNB4 | -9556 |
| CTSB | -9530 |
| SLC2A3 | -9521 |
| SIGLEC9 | -9512 |
| NFAM1 | -9480 |
| B4GALT1 | -9470 |
| ENPP4 | -9450 |
| PRSS3 | -9386 |
| VAPA | -9336 |
| CEACAM6 | -9322 |
| TMEM30A | -9317 |
| HLA-A | -9216 |
| NRAS | -9056 |
| GUSB | -9054 |
| CANT1 | -9052 |
| SERPINB6 | -9007 |
| FTH1 | -8939 |
| RAB3D | -8919 |
| SVIP | -8918 |
| OSCAR | -8819 |
| MVP | -8815 |
| ATP6V0A1 | -8805 |
| TOM1 | -8801 |
| RAB7A | -8782 |
| NCKAP1L | -8756 |
| MIF | -8741 |
| GPI | -8663 |
| RAB3A | -8649 |
| BST1 | -8638 |
| CD33 | -8566 |
| RAC1 | -8501 |
| GPR84 | -8494 |
| GYG1 | -8407 |
| AHSG | -8346 |
| STBD1 | -8329 |
| PSMB7 | -8319 |
| CEACAM8 | -8306 |
| CLEC4C | -8243 |
| MAPK14 | -8203 |
| ADAM8 | -8173 |
| SLPI | -8072 |
| PPIA | -8002 |
| RHOA | -7993 |
| PECAM1 | -7988 |
| PTAFR | -7971 |
| NPC2 | -7879 |
| CYFIP1 | -7795 |
| NFKB1 | -7717 |
| GMFG | -7690 |
| OLR1 | -7605 |
| SIGLEC14 | -7584 |
| PGAM1 | -7574 |
| SERPINB1 | -7540 |
| SCAMP1 | -7530 |
| BST2 | -7399 |
| MGST1 | -7244 |
| NCSTN | -7234 |
| SLC2A5 | -7085 |
| CD177 | -7035 |
| GAA | -6922 |
| HPSE | -6776 |
| CDA | -6771 |
| PTPRJ | -6741 |
| RAB4B | -6656 |
| DERA | -6640 |
| CLEC12A | -6595 |
| DNAJC3 | -6592 |
| HSPA1A | -6581 |
| CTSZ | -6514 |
| ANXA2 | -6503 |
| HRNR | -6473 |
| FUCA1 | -6418 |
| FTL | -6388 |
| CD47 | -6354 |
| PRCP | -6327 |
| SERPINA3 | -6321 |
| SNAP25 | -6279 |
| IDH1 | -6272 |
| TICAM2 | -6240 |
| CD58 | -6149 |
| STOM | -6138 |
| PSMD14 | -6115 |
| UNC13D | -6108 |
| B2M | -6084 |
| MAPK1 | -6079 |
| APAF1 | -6062 |
| CCT2 | -5934 |
| TRPM2 | -5932 |
| ITGAM | -5917 |
| CPNE1 | -5885 |
| IQGAP1 | -5864 |
| JUP | -5858 |
| PDAP1 | -5800 |
| HMGB1 | -5752 |
| ERP44 | -5696 |
| HGSNAT | -5672 |
| HMOX2 | -5659 |
| TMBIM1 | -5570 |
| RAB24 | -5500 |
| CPPED1 | -5468 |
| SLC44A2 | -5361 |
| FCER1G | -5297 |
| HEBP2 | -5296 |
| S100A11 | -5262 |
| SPTAN1 | -5203 |
| SNAP29 | -5190 |
| PSMD7 | -5158 |
| FPR1 | -5112 |
| STK11IP | -5106 |
| ACLY | -5064 |
| RAB6A | -5055 |
| RNASE2 | -5014 |
| YPEL5 | -4855 |
| ITGAV | -4786 |
| CD63 | -4710 |
| LAMTOR1 | -4695 |
| COPB1 | -4689 |
| FPR2 | -4671 |
| CPNE3 | -4657 |
| LILRB3 | -4575 |
| IQGAP2 | -4528 |
| HSPA1B | -4491 |
| SERPINB10 | -4476 |
| ARSB | -4422 |
| SLCO4C1 | -4348 |
| PRKCD | -4339 |
| ARMC8 | -4315 |
| C6orf120 | -4277 |
| TIMP2 | -4253 |
| VCP | -4221 |
| FCGR2A | -4179 |
| AP1M1 | -4178 |
| RAP2B | -4176 |
| CRISPLD2 | -4145 |
| RAB37 | -4129 |
| STK10 | -4011 |
| RAB18 | -3976 |
| IMPDH1 | -3971 |
| NHLRC3 | -3939 |
| PSMD11 | -3936 |
| RAB31 | -3923 |
| KRT1 | -3821 |
| ATG7 | -3780 |
| TMEM179B | -3778 |
| DDOST | -3727 |
| DOCK2 | -3690 |
| BPI | -3663 |
| ANO6 | -3646 |
| NEU1 | -3479 |
| CFD | -3456 |
| ARG1 | -3412 |
| ALDOA | -3343 |
| LTF | -3342 |
| GRN | -3338 |
| SDCBP | -3305 |
| CKAP4 | -3302 |
| ROCK1 | -3299 |
| SNAP23 | -3277 |
| PLAC8 | -3202 |
| FGL2 | -3167 |
| KPNB1 | -3143 |
| COMMD9 | -2948 |
| IRAG2 | -2895 |
| DIAPH1 | -2889 |
| GCA | -2880 |
| DEGS1 | -2851 |
| C5AR1 | -2800 |
| PYCARD | -2753 |
| CAPN1 | -2688 |
| GOLGA7 | -2677 |
| ABCA13 | -2595 |
| CD68 | -2546 |
| MAN2B1 | -2531 |
| CTSS | -2467 |
| GALNS | -2454 |
| SIRPA | -2352 |
| C1orf35 | -2310 |
| HLA-B | -2277 |
| LILRB2 | -2262 |
| APRT | -2222 |
| PRDX6 | -2193 |
| ADGRG3 | -2056 |
| PRTN3 | -2041 |
| ITGAL | -2024 |
| PLAUR | -2012 |
| PSMA2 | -1982 |
| GM2A | -1908 |
| CYSTM1 | -1894 |
| PGLYRP1 | -1886 |
| SERPINA1 | -1802 |
| AP2A2 | -1773 |
| CD59 | -1661 |
| MGAM | -1648 |
| IMPDH2 | -1455 |
| SURF4 | -1326 |
| IGF2R | -1310 |
| CAND1 | -1292 |
| DYNC1H1 | -1161 |
| LAIR1 | -1133 |
| CCT8 | -994 |
| RNASET2 | -993 |
| PYGB | -911 |
| HBB | -860 |
| RAP1A | -776 |
| LGALS3 | -717 |
| PSMB1 | -649 |
| TUBB4B | -641 |
| FLG2 | -605 |
| OSTF1 | -472 |
| SLC15A4 | -417 |
| CD44 | -393 |
| ALOX5 | -349 |
| AGA | -324 |
| ADAM10 | -322 |
| HK3 | -306 |
| DYNC1LI1 | -283 |
| PSMD13 | -227 |
| VPS35L | -200 |
| PGM2 | -188 |
| EEF1A1 | -169 |
| XRCC6 | -18 |
| PSAP | 108 |
| PGM1 | 109 |
| PSMD6 | 166 |
| CREG1 | 208 |
| CD53 | 210 |
| PPIE | 429 |
| CSNK2B | 434 |
| PSMD2 | 438 |
| CRACR2A | 495 |
| HSP90AA1 | 498 |
| PDXK | 560 |
| CR1 | 588 |
| MMP9 | 632 |
| CTSA | 663 |
| QSOX1 | 666 |
| PKM | 696 |
| DSP | 720 |
| ANPEP | 783 |
| ATP8A1 | 794 |
| GNS | 893 |
| AGL | 905 |
| FUCA2 | 967 |
| ACTR10 | 974 |
| PSMC2 | 1115 |
| PSMD1 | 1119 |
| PLEKHO2 | 1148 |
| PTPRC | 1183 |
| QPCT | 1209 |
| PTPRN2 | 1227 |
| HSPA6 | 1232 |
| CAB39 | 1473 |
| CXCR2 | 1512 |
| GSN | 1576 |
| DGAT1 | 1578 |
| NDUFC2 | 1597 |
| PFKL | 1650 |
| ITGB2 | 1695 |
| PIGR | 1733 |
| NIT2 | 1755 |
| CDK13 | 1757 |
| RAB44 | 1783 |
| TXNDC5 | 1866 |
| DEFA4 | 1922 |
| KCMF1 | 1940 |
| AMPD3 | 1991 |
| GDI2 | 2006 |
| CSTB | 2024 |
| CTSH | 2150 |
| EEF2 | 2157 |
| MMP25 | 2195 |
| S100P | 2282 |
| NFASC | 2347 |
| LRRC7 | 2386 |
| RHOF | 2412 |
| DPP7 | 2430 |
| ARL8A | 2478 |
| PSMD12 | 2494 |
| ACTR2 | 2584 |
| TRAPPC1 | 2657 |
| VAMP8 | 2687 |
| SYNGR1 | 2694 |
| ORM2 | 2766 |
| RAB5C | 2816 |
| SLC11A1 | 2875 |
| CAMP | 2901 |
| NBEAL2 | 2958 |
| LPCAT1 | 2980 |
| RAB10 | 3030 |
| PNP | 3069 |
| MANBA | 3097 |
| GSDMD | 3114 |
| ATP11B | 3236 |
| FCN1 | 3271 |
| FABP5 | 3303 |
| RHOG | 3326 |
| ITGAX | 3356 |
| DYNLT1 | 3429 |
| ATP11A | 3463 |
| OLFM4 | 3525 |
| TOLLIP | 3534 |
| GLB1 | 3562 |
| ARPC5 | 3563 |
| XRCC5 | 3659 |
| MME | 3675 |
| DNAJC5 | 3699 |
| ATP6V0C | 3790 |
| PRG2 | 3894 |
| DBNL | 3923 |
| KCNAB2 | 3924 |
| RAB14 | 4054 |
| HEXB | 4073 |
| CHI3L1 | 4080 |
| RAB5B | 4118 |
| TMEM63A | 4182 |
| CYBA | 4195 |
| HSPA8 | 4201 |
| A1BG | 4242 |
| PKP1 | 4262 |
| S100A12 | 4390 |
| FAF2 | 4459 |
| CALML5 | 4510 |
| NAPRT | 4709 |
| IST1 | 4793 |
| HLA-C | 4893 |
| ORM1 | 4997 |
| PTPN6 | 5005 |
| LAMP1 | 5015 |
| TMC6 | 5132 |
| CLEC4D | 5154 |
| CD36 | 5163 |
| ARSA | 5204 |
| CMTM6 | 5223 |
| CAP1 | 5344 |
| DNAJC13 | 5472 |
| MCEMP1 | 5508 |
| ARHGAP45 | 5514 |
| LTA4H | 5548 |
| TLR2 | 5585 |
| PSEN1 | 5639 |
| RAB27A | 5652 |
| PTPRB | 5734 |
| ALDOC | 5770 |
| AOC1 | 5771 |
| PADI2 | 5952 |
| ACTR1B | 5991 |
| HSP90AB1 | 6061 |
| PAFAH1B2 | 6094 |
| APEH | 6123 |
| DSN1 | 6194 |
| ATP6V1D | 6253 |
| LILRA3 | 6345 |
| FRK | 6360 |
| UBR4 | 6390 |
| HVCN1 | 6522 |
| TNFRSF1B | 6580 |
| CLEC5A | 6883 |
| PSMD3 | 6889 |
| ACAA1 | 6926 |
| CD55 | 7097 |
| TCIRG1 | 7186 |
| COTL1 | 7237 |
| PTX3 | 7277 |
| CTSC | 7289 |
| CEP290 | 7327 |
| FCAR | 7473 |
| ILF2 | 7531 |
| ASAH1 | 7557 |
| ATP8B4 | 7668 |
| ATAD3B | 7679 |
| CST3 | 7834 |
| PYGL | 7851 |
| CRISP3 | 7919 |
| CNN2 | 7973 |
| PLD1 | 8058 |
| TCN1 | 8065 |
| PSMC3 | 8087 |
| PA2G4 | 8102 |
| ARHGAP9 | 8328 |
| ADGRE5 | 8456 |
| CD14 | 8569 |
| ACP3 | 8699 |
| C3 | 8800 |
| PTGES2 | 8823 |
| CXCR1 | 8889 |
| TTR | 8913 |
| CHIT1 | 8919 |
| DSC1 | 8943 |
| TBC1D10C | 8945 |
| CAT | 9052 |
| SERPINB12 | 9075 |
| CD93 | 9142 |
| MMP8 | 9198 |
| ADGRE3 | 9363 |
| PPBP | 9375 |
| SLC27A2 | 9377 |
| VNN1 | 9418 |
| LCN2 | 9447 |
| C3AR1 | 9470 |
| SRP14 | 9527 |
| RETN | 9539 |
| PRG3 | 9917 |
| CXCL1 | 9982 |
| SERPINB3 | 10078 |
REACTOME_OLFACTORY_SIGNALING_PATHWAY
| 628 | |
|---|---|
| set | REACTOME_OLFACTORY_SIGNALING_PATHWAY |
| setSize | 348 |
| pANOVA | 0.000305 |
| s.dist | 0.113 |
| p.adjustANOVA | 0.0557 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| OR6C4 | 10137 |
| OR6C65 | 10050 |
| OR7A10 | 10048 |
| OR2F2 | 10039 |
| OR10S1 | 10038 |
| OR2T3 | 10015 |
| OR1L4 | 9989 |
| OR1S2 | 9952 |
| OR5AK2 | 9881 |
| OR5K3 | 9872 |
| OR4X2 | 9855 |
| OR5AR1 | 9842 |
| OR10A7 | 9835 |
| OR1N1 | 9834 |
| OR1E2 | 9833 |
| OR2T33 | 9828 |
| OR3A3 | 9825 |
| OR8G5 | 9817 |
| OR2AK2 | 9807 |
| OR56A4 | 9805 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| OR6C4 | 10137.0 |
| OR6C65 | 10050.0 |
| OR7A10 | 10048.0 |
| OR2F2 | 10039.0 |
| OR10S1 | 10038.0 |
| OR2T3 | 10015.0 |
| OR1L4 | 9989.0 |
| OR1S2 | 9952.0 |
| OR5AK2 | 9881.0 |
| OR5K3 | 9872.0 |
| OR4X2 | 9855.0 |
| OR5AR1 | 9842.0 |
| OR10A7 | 9835.0 |
| OR1N1 | 9834.0 |
| OR1E2 | 9833.0 |
| OR2T33 | 9828.0 |
| OR3A3 | 9825.0 |
| OR8G5 | 9817.0 |
| OR2AK2 | 9807.0 |
| OR56A4 | 9805.0 |
| OR6A2 | 9780.0 |
| OR52H1 | 9739.0 |
| OR10T2 | 9734.0 |
| OR2AG2 | 9728.0 |
| OR5AU1 | 9721.0 |
| OR4X1 | 9708.0 |
| OR2V1 | 9698.0 |
| OR6Y1 | 9694.0 |
| OR6F1 | 9672.0 |
| OR56B4 | 9657.0 |
| OR1M1 | 9652.0 |
| OR52E6 | 9632.0 |
| OR10W1 | 9607.0 |
| RTP2 | 9594.0 |
| OR8B8 | 9589.0 |
| OR2M2 | 9588.0 |
| OR10G2 | 9582.0 |
| OR1E1 | 9540.0 |
| OR2T12 | 9511.0 |
| OR6K3 | 9510.0 |
| CNGA4 | 9503.0 |
| OR2L3 | 9497.0 |
| OR4D9 | 9491.0 |
| OR51E1 | 9482.0 |
| OR6C74 | 9477.0 |
| OR5K4 | 9453.0 |
| OR52L1 | 9440.0 |
| OR51G2 | 9421.0 |
| OR5K2 | 9395.0 |
| OR14I1 | 9368.0 |
| OR5H2 | 9358.0 |
| OR8G1 | 9351.0 |
| OR10X1 | 9337.0 |
| OR2AT4 | 9328.0 |
| OR8U3 | 9322.0 |
| OR2AP1 | 9307.0 |
| OR1K1 | 9230.0 |
| OR2G6 | 9196.0 |
| OR6Q1 | 9187.0 |
| OR9K2 | 9150.0 |
| OR10V1 | 9127.0 |
| OR8S1 | 9118.0 |
| OR4M1 | 9093.0 |
| OR4B1 | 9070.0 |
| OR5T2 | 9069.0 |
| OR6C3 | 9044.0 |
| OR5V1 | 9035.0 |
| OR4K13 | 9030.0 |
| OR8D4 | 8988.0 |
| OR1J4 | 8982.0 |
| OR13D1 | 8979.0 |
| OR7G2 | 8966.0 |
| OR11H6 | 8930.0 |
| OR7A17 | 8923.0 |
| OR10Q1 | 8883.0 |
| OR9I1 | 8873.0 |
| OR5M3 | 8813.0 |
| OR2T11 | 8805.0 |
| OR10Z1 | 8794.0 |
| OR5L2 | 8768.0 |
| OR4C16 | 8762.0 |
| OR4D6 | 8711.0 |
| OR2F1 | 8709.0 |
| OR1A2 | 8672.0 |
| OR51Q1 | 8642.0 |
| OR7G3 | 8637.0 |
| RTP1 | 8621.0 |
| OR5AN1 | 8616.0 |
| OR2T4 | 8592.0 |
| OR4C45 | 8571.0 |
| OR1B1 | 8515.0 |
| OR10J3 | 8493.0 |
| OR10G9 | 8488.0 |
| OR52N1 | 8467.0 |
| OR6C2 | 8448.0 |
| OR2T6 | 8378.0 |
| OR6C1 | 8239.0 |
| OR9A4 | 8200.0 |
| OR2T8 | 8142.0 |
| OR1L1 | 8039.0 |
| OR51B2 | 8032.0 |
| OR5F1 | 7993.0 |
| OR52B2 | 7964.0 |
| OR51T1 | 7899.0 |
| OR1C1 | 7824.0 |
| OR51S1 | 7704.0 |
| OR2L13 | 7644.0 |
| OR6C6 | 7637.0 |
| OR6C75 | 7582.0 |
| OR6N1 | 7400.0 |
| OR6P1 | 7380.0 |
| OR2J2 | 7378.0 |
| OR10C1 | 7269.0 |
| OR2AG1 | 7257.0 |
| OR2B2 | 7255.0 |
| OR52D1 | 7145.0 |
| OR7C2 | 7012.0 |
| OR2L2 | 6846.0 |
| OR5D18 | 6809.0 |
| OR51L1 | 6604.0 |
| OR51A2 | 6599.0 |
| GNB1 | 6594.0 |
| REEP1 | 6540.0 |
| OR14J1 | 6472.0 |
| OR51I1 | 6459.0 |
| OR51E2 | 6411.0 |
| OR10H2 | 6405.0 |
| OR5D13 | 6398.0 |
| OR4C46 | 6395.0 |
| OR2H2 | 6322.0 |
| OR5D16 | 6294.0 |
| OR5B17 | 6201.0 |
| OR13C8 | 6125.0 |
| OR2T27 | 6075.0 |
| OR2K2 | 6052.0 |
| OR51V1 | 5947.0 |
| OR6S1 | 5930.0 |
| OR13C9 | 5700.0 |
| OR2L8 | 5442.0 |
| OR13A1 | 5302.0 |
| OR10J5 | 5126.0 |
| OR2B11 | 5029.0 |
| OR2M5 | 4992.0 |
| OR2S2 | 4749.0 |
| CNGB1 | 4738.0 |
| LDB1 | 4442.0 |
| GNG13 | 4355.0 |
| OR52W1 | 4230.0 |
| OR11L1 | 4149.0 |
| OR4N5 | 4139.0 |
| OR2A2 | 3838.0 |
| OR8B2 | 3812.0 |
| OR4A16 | 3568.0 |
| OR7D4 | 3435.0 |
| OR56A3 | 3399.0 |
| OR5M10 | 3384.0 |
| OR51A7 | 3330.0 |
| OR5C1 | 3009.0 |
| OR4K2 | 2900.0 |
| ANO2 | 2765.0 |
| OR11G2 | 2756.0 |
| OR3A1 | 2734.0 |
| OR10H4 | 2725.0 |
| OR7D2 | 2706.0 |
| OR52B6 | 2522.0 |
| OR8I2 | 2472.0 |
| OR6C70 | 2414.0 |
| OR2H1 | 2391.0 |
| OR10H3 | 2371.0 |
| EBF1 | 2363.0 |
| OR5T3 | 2361.0 |
| OR2Z1 | 2271.0 |
| OR5H6 | 1226.0 |
| OR51B6 | 1136.0 |
| OR7C1 | 1083.0 |
| OR9Q2 | 958.0 |
| OR1F1 | 566.0 |
| OR8K3 | 462.0 |
| OR1S1 | 452.0 |
| OR2T1 | 319.0 |
| OR1L3 | 224.0 |
| OR4K14 | 196.0 |
| GNAL | 162.0 |
| OR52E4 | 104.0 |
| LHX2 | 93.0 |
| OR8J3 | -19.0 |
| OR5D14 | -138.0 |
| OR2W1 | -205.0 |
| OR6T1 | -313.0 |
| OR52I1 | -355.0 |
| OR5H15 | -436.0 |
| OR2Y1 | -566.0 |
| OR12D3 | -764.0 |
| OR5P2 | -916.0 |
| OR5M1 | -1128.0 |
| OR5K1 | -1724.0 |
| OR5A1 | -1741.0 |
| OR2G3 | -1754.0 |
| OR11H4 | -1808.0 |
| OR52I2 | -1814.0 |
| OR51B5 | -1927.0 |
| OR5L1 | -1934.0 |
| OR4D2 | -1986.0 |
| OR14C36 | -1992.0 |
| OR4K5 | -1995.0 |
| OR2M3 | -2026.0 |
| OR6K2 | -2108.0 |
| OR8D2 | -2210.0 |
| OR6C76 | -2259.0 |
| OR2M4 | -2349.0 |
| OR4D10 | -2430.0 |
| OR4D5 | -2597.0 |
| OR9Q1 | -2718.0 |
| OR1J2 | -2720.0 |
| OR14A16 | -2759.0 |
| OR5M8 | -2897.0 |
| OR8D1 | -2968.0 |
| OR10A5 | -3101.0 |
| OR2D2 | -3215.0 |
| OR8H3 | -3413.0 |
| OR8K5 | -3428.0 |
| OR5T1 | -3492.0 |
| OR4L1 | -3556.0 |
| ADCY3 | -3624.0 |
| OR10A2 | -3644.0 |
| OR52R1 | -3941.0 |
| OR3A2 | -4146.0 |
| OR4K17 | -4266.0 |
| OR52E8 | -4925.0 |
| OR6B3 | -4983.0 |
| OR6K6 | -5095.0 |
| OR4A5 | -5136.0 |
| OR10G7 | -5216.0 |
| OR1D2 | -5492.0 |
| OR4F6 | -5516.0 |
| OR6C68 | -5568.0 |
| OR4N2 | -5615.0 |
| OR1L8 | -5692.0 |
| OR7E24 | -5722.0 |
| OR1A1 | -5832.0 |
| OR12D2 | -5887.0 |
| OR2B6 | -5931.0 |
| OR4F15 | -6018.0 |
| OR1J1 | -6238.0 |
| OR6M1 | -6341.0 |
| OR13C3 | -6353.0 |
| OR52K1 | -6465.0 |
| OR4A15 | -6601.0 |
| OR6B1 | -6643.0 |
| OR5I1 | -6712.0 |
| OR1I1 | -6716.0 |
| OR52J3 | -6790.0 |
| OR13C2 | -6793.0 |
| OR10G4 | -6858.0 |
| OR5B12 | -7105.0 |
| OR4C6 | -7193.0 |
| OR52M1 | -7351.0 |
| OR4D1 | -7473.0 |
| OR51F1 | -7494.0 |
| OR9A2 | -7528.0 |
| OR10K1 | -7538.0 |
| OR1N2 | -7572.0 |
| OR10H5 | -7665.0 |
| OR5B21 | -7709.0 |
| OR5W2 | -7896.0 |
| OR56A1 | -7913.0 |
| OR9G4 | -8215.0 |
| OR5AC2 | -8291.0 |
| OR6X1 | -8310.0 |
| OR2AE1 | -8353.0 |
| OR8U1 | -8445.0 |
| OR8U8 | -8614.0 |
| OR10A4 | -8624.0 |
| OR2A5 | -8777.0 |
| OR5AS1 | -8865.0 |
| OR10G3 | -8945.0 |
| OR13G1 | -8950.0 |
| OR10AD1 | -8965.0 |
| OR6N2 | -9041.0 |
| OR4C15 | -9121.0 |
| OR8K1 | -9146.0 |
| OR52A1 | -9236.0 |
| OR2D3 | -9318.0 |
| OR2L5 | -9329.0 |
| OR1L6 | -9414.0 |
| OR51I2 | -9442.0 |
| OR1G1 | -9451.0 |
| OR5B3 | -9550.0 |
| OR52K2 | -9596.0 |
| OR10J1 | -9602.0 |
| OR2C3 | -9641.0 |
| OR10A3 | -9687.0 |
| OR7A5 | -9724.0 |
| OR51G1 | -9742.0 |
| OR6B2 | -9797.0 |
| OR4S1 | -9864.0 |
| OR10AG1 | -9883.0 |
| OR5P3 | -10015.0 |
| OR51F2 | -10059.0 |
| OR8B12 | -10078.0 |
| OR8J1 | -10117.0 |
| OR52A5 | -10160.0 |
| OR1Q1 | -10161.0 |
| OR2A14 | -10206.0 |
| OR56A5 | -10211.0 |
| OR4C12 | -10242.0 |
| OR56B1 | -10342.0 |
| OR4K1 | -10352.0 |
| OR51M1 | -10377.0 |
| OR4K15 | -10527.0 |
| OR4C3 | -10548.0 |
| OR2B3 | -10559.0 |
| OR2C1 | -10598.0 |
| OR10P1 | -10606.0 |
| OR52E2 | -10639.0 |
| OR51B4 | -10702.0 |
| OR13F1 | -10711.0 |
| OR2W3 | -10852.0 |
| OR11A1 | -10872.0 |
| OR4E2 | -10997.0 |
| OR5B2 | -11054.0 |
| OR5J2 | -11058.0 |
| OR51D1 | -11098.0 |
| OR10G8 | -11102.0 |
| OR2G2 | -11146.0 |
| OR13J1 | -11186.0 |
| OR10H1 | -11188.0 |
| OR10K2 | -11204.0 |
| OR5AP2 | -11227.0 |
| OR8H1 | -11248.0 |
| OR5M11 | -11294.0 |
| OR6V1 | -11296.0 |
| OR10A6 | -11308.0 |
| OR52N2 | -11328.0 |
| OR8B4 | -11334.0 |
| OR5M9 | -11358.0 |
| OR9G1 | -11436.5 |
| OR9G9 | -11436.5 |
| OR2V2 | -11525.0 |
| OR4A47 | -11570.0 |
| OR13C4 | -11592.0 |
| OR2A12 | -11629.0 |
| OR8A1 | -11634.0 |
| OR5A2 | -11666.0 |
| OR7G1 | -11749.0 |
| OR4D11 | -11786.0 |
| OR5H1 | -11819.0 |
| OR2M7 | -11826.0 |
REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION
| 1024 | |
|---|---|
| set | REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION |
| setSize | 1356 |
| pANOVA | 0.000804 |
| s.dist | -0.0542 |
| p.adjustANOVA | 0.132 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| BPIFB2 | -11660 |
| AREG | -11608 |
| FCGR3B | -11603 |
| TUBB8 | -11590 |
| MUC3A | -11573 |
| SPACA4 | -11518 |
| TRIM4 | -11376 |
| PRSS41 | -11367 |
| CISH | -11365 |
| FBXO40 | -11353 |
| SUMO2 | -11339 |
| PDIA3 | -11324 |
| PSMB11 | -11321 |
| KDELR1 | -11305 |
| APOE | -11264 |
| AMBN | -11216 |
| H2BC14 | -11198 |
| EEF2KMT | -11195 |
| DPM3 | -11190 |
| SOCS3 | -11181 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| BPIFB2 | -11660.0 |
| AREG | -11608.0 |
| FCGR3B | -11603.0 |
| TUBB8 | -11590.0 |
| MUC3A | -11573.0 |
| SPACA4 | -11518.0 |
| TRIM4 | -11376.0 |
| PRSS41 | -11367.0 |
| CISH | -11365.0 |
| FBXO40 | -11353.0 |
| SUMO2 | -11339.0 |
| PDIA3 | -11324.0 |
| PSMB11 | -11321.0 |
| KDELR1 | -11305.0 |
| APOE | -11264.0 |
| AMBN | -11216.0 |
| H2BC14 | -11198.0 |
| EEF2KMT | -11195.0 |
| DPM3 | -11190.0 |
| SOCS3 | -11181.0 |
| ST6GALNAC1 | -11158.0 |
| RAB21 | -11099.0 |
| RAB34 | -11047.0 |
| KEAP1 | -11041.0 |
| GFPT1 | -10977.0 |
| BMI1 | -10976.0 |
| MUC17 | -10933.0 |
| MPI | -10927.0 |
| VDAC3 | -10890.0 |
| SPP2 | -10887.0 |
| FBXW4 | -10879.0 |
| TUBA4A | -10847.0 |
| UBE2E3 | -10821.0 |
| KBTBD7 | -10811.0 |
| ETFB | -10805.0 |
| CAPZA2 | -10797.0 |
| SUMF2 | -10751.0 |
| NEU3 | -10750.0 |
| IGFBP1 | -10745.0 |
| SUMO1 | -10728.0 |
| UBE2E1 | -10694.0 |
| MAN1C1 | -10614.0 |
| MOGS | -10607.0 |
| TUBB4A | -10582.0 |
| SENP5 | -10531.0 |
| RAD23A | -10503.0 |
| TMED2 | -10492.0 |
| H2AC14 | -10482.0 |
| MLEC | -10442.0 |
| UBE2S | -10441.0 |
| TTLL8 | -10439.0 |
| RPN1 | -10438.0 |
| CD52 | -10436.0 |
| GOLGA2 | -10423.0 |
| AAAS | -10372.0 |
| COMMD3 | -10370.0 |
| NICN1 | -10365.0 |
| PIGX | -10350.0 |
| GOSR1 | -10334.0 |
| LY6E | -10325.0 |
| RAB23 | -10317.0 |
| GALNT15 | -10305.0 |
| VDAC1 | -10292.0 |
| BAP1 | -10250.0 |
| ASB8 | -10245.0 |
| GPLD1 | -10241.0 |
| WSB2 | -10237.0 |
| POMK | -10219.0 |
| PSMB9 | -10214.0 |
| PSMA5 | -10194.0 |
| GALNT1 | -10181.0 |
| ST6GALNAC6 | -10153.0 |
| DYNLL1 | -10134.0 |
| CALR | -10123.0 |
| RAD18 | -10106.0 |
| B4GALT5 | -10091.0 |
| COG7 | -10066.0 |
| PNPLA2 | -10013.0 |
| KLHL42 | -10006.0 |
| RCE1 | -9988.0 |
| FOLR1 | -9963.0 |
| SMC6 | -9912.0 |
| PGAP1 | -9911.0 |
| PRMT3 | -9901.0 |
| TNIP2 | -9889.0 |
| COMMD7 | -9879.0 |
| PIGU | -9870.0 |
| NOD1 | -9854.0 |
| PSMB8 | -9839.0 |
| COPS8 | -9834.0 |
| FBXL18 | -9827.0 |
| GALNT4 | -9813.0 |
| UBE2J2 | -9795.0 |
| RAB43 | -9794.0 |
| CNIH2 | -9779.0 |
| GPAA1 | -9678.0 |
| IGFBP4 | -9667.0 |
| PIGY | -9663.0 |
| H2AC6 | -9658.0 |
| MUC15 | -9635.0 |
| SERPIND1 | -9623.0 |
| FN3KRP | -9607.0 |
| FBXO9 | -9601.0 |
| GATA3 | -9591.0 |
| MBTPS1 | -9589.0 |
| RAB26 | -9544.0 |
| RAB11B | -9528.0 |
| UBA2 | -9517.0 |
| CYLD | -9497.0 |
| CBX2 | -9496.0 |
| PROS1 | -9491.0 |
| SLC17A5 | -9489.0 |
| UBE2G1 | -9475.0 |
| B4GALT1 | -9470.0 |
| RBX1 | -9464.0 |
| TTLL2 | -9430.0 |
| PIGS | -9419.0 |
| SLC35C1 | -9394.0 |
| ENAM | -9382.0 |
| TOMM70 | -9366.0 |
| TUBA4B | -9365.0 |
| PIGP | -9339.0 |
| YKT6 | -9333.0 |
| DPP3 | -9298.0 |
| PIGZ | -9239.0 |
| HLA-A | -9216.0 |
| USP5 | -9202.0 |
| B3GNT3 | -9182.0 |
| DCAF17 | -9162.0 |
| GALNT8 | -9156.0 |
| UBA6 | -9129.0 |
| AMTN | -9124.0 |
| GALNT6 | -9111.0 |
| EVA1A | -9061.0 |
| NR1H2 | -9028.0 |
| UBXN1 | -9023.0 |
| ASB16 | -9015.0 |
| EEF1AKMT1 | -8979.0 |
| RAB3B | -8968.0 |
| FBXO4 | -8966.0 |
| MUCL1 | -8963.0 |
| NCOA2 | -8959.0 |
| STAMBPL1 | -8947.0 |
| APOA1 | -8926.0 |
| ASB1 | -8924.0 |
| RAB3D | -8919.0 |
| COG2 | -8908.0 |
| RANBP2 | -8901.0 |
| KTN1 | -8883.0 |
| TGOLN2 | -8867.0 |
| RNF103 | -8863.0 |
| PMM1 | -8861.0 |
| CAPZA3 | -8856.0 |
| SVBP | -8847.0 |
| VDAC2 | -8841.0 |
| LRRC49 | -8800.0 |
| CDKN2A | -8793.0 |
| SMC3 | -8792.0 |
| STAM | -8791.0 |
| UBB | -8790.0 |
| RAB7A | -8782.0 |
| MATN3 | -8771.0 |
| THY1 | -8762.0 |
| AMFR | -8702.0 |
| B4GALT2 | -8692.0 |
| CEACAM7 | -8680.0 |
| DPH5 | -8653.0 |
| PIGV | -8652.0 |
| RAB3A | -8649.0 |
| BST1 | -8638.0 |
| TRAPPC6A | -8621.0 |
| TTLL6 | -8613.0 |
| LMAN1L | -8536.0 |
| APOA2 | -8526.0 |
| THSD7B | -8516.0 |
| TOP1 | -8502.0 |
| NUP98 | -8487.0 |
| CDC25A | -8476.0 |
| SAFB | -8469.0 |
| AXIN2 | -8455.0 |
| METTL22 | -8439.0 |
| MGAT4B | -8425.0 |
| FBXO32 | -8422.0 |
| NUP50 | -8418.0 |
| DPM1 | -8404.0 |
| RABGGTB | -8399.0 |
| ZNF131 | -8392.0 |
| SOCS2 | -8373.0 |
| AHSG | -8346.0 |
| LYPD4 | -8334.0 |
| RAB11A | -8333.0 |
| NAPA | -8332.0 |
| PSMB7 | -8319.0 |
| OTUB1 | -8296.0 |
| FBXO10 | -8279.0 |
| UBE2H | -8268.0 |
| USP12 | -8251.0 |
| B3GNT4 | -8231.0 |
| SIAH2 | -8177.0 |
| PSME1 | -8170.0 |
| RAB30 | -8169.0 |
| LRRC41 | -8160.0 |
| ACTR5 | -8153.0 |
| RNF7 | -8107.0 |
| TGFB1 | -8082.0 |
| COPG1 | -8078.0 |
| TTLL7 | -8073.0 |
| KBTBD8 | -8064.0 |
| UBE2N | -8046.0 |
| DAG1 | -8042.0 |
| GP2 | -8024.0 |
| VHL | -8019.0 |
| YY1 | -8000.0 |
| RHOA | -7993.0 |
| PSMB6 | -7992.0 |
| PRND | -7944.0 |
| SENP8 | -7927.0 |
| MAP3K7 | -7914.0 |
| UBE2Q2 | -7895.0 |
| TTLL3 | -7860.0 |
| TMED9 | -7847.0 |
| ADAMTS10 | -7825.0 |
| RANGAP1 | -7783.0 |
| ANKRD9 | -7781.0 |
| KLHL22 | -7774.0 |
| DCTN2 | -7699.0 |
| UBE2W | -7697.0 |
| COPS3 | -7685.0 |
| RAB40C | -7680.0 |
| BTBD6 | -7679.0 |
| PUM2 | -7675.0 |
| ABRAXAS2 | -7660.0 |
| TRIM25 | -7651.0 |
| FBXO15 | -7637.0 |
| H4C1 | -7603.0 |
| GNE | -7599.0 |
| DNMT3B | -7595.0 |
| INO80B | -7580.0 |
| RPN2 | -7560.0 |
| TRAF2 | -7547.0 |
| ZRANB1 | -7504.0 |
| DOLPP1 | -7452.0 |
| ADAMTS7 | -7440.0 |
| COPB2 | -7408.0 |
| RAB12 | -7401.0 |
| USP49 | -7395.0 |
| LRR1 | -7388.0 |
| CDKN1A | -7378.0 |
| TFG | -7358.0 |
| DCUN1D1 | -7352.0 |
| NAE1 | -7333.0 |
| SOCS5 | -7311.0 |
| ADAMTS17 | -7303.0 |
| COPZ1 | -7291.0 |
| FUT3 | -7277.0 |
| USP19 | -7266.0 |
| PDIA6 | -7257.0 |
| NUP37 | -7243.0 |
| ST3GAL3 | -7236.0 |
| CPM | -7225.0 |
| COPS5 | -7224.0 |
| FBXW8 | -7200.0 |
| PSMC4 | -7169.0 |
| FEM1B | -7147.0 |
| TTLL1 | -7126.0 |
| ACTR1A | -7122.0 |
| NUP153 | -7121.0 |
| ST8SIA1 | -7120.0 |
| PIGQ | -7111.0 |
| COMMD4 | -7110.0 |
| RAB19 | -7109.0 |
| APC | -7106.0 |
| PPP6R3 | -7061.0 |
| SEC22A | -7017.0 |
| KLHL41 | -6993.0 |
| MCFD2 | -6982.0 |
| WAC | -6972.0 |
| CUL3 | -6971.0 |
| CMAS | -6937.0 |
| LYPD5 | -6933.0 |
| B4GALT3 | -6932.0 |
| B3GNT2 | -6931.0 |
| ANKRD28 | -6909.0 |
| C1GALT1 | -6892.0 |
| RAD21 | -6890.0 |
| ASXL1 | -6853.0 |
| LMO7 | -6825.0 |
| NR3C2 | -6818.0 |
| SENP2 | -6784.0 |
| NEU2 | -6773.0 |
| RAB2A | -6772.0 |
| NUP155 | -6680.0 |
| RAB4B | -6656.0 |
| CLSPN | -6637.0 |
| FBXL12 | -6609.0 |
| DNAJC3 | -6592.0 |
| KDELR2 | -6588.0 |
| GCNT7 | -6583.0 |
| PIAS1 | -6572.0 |
| APOA5 | -6567.0 |
| COP1 | -6566.0 |
| PSME3 | -6558.0 |
| ASB5 | -6553.0 |
| STAM2 | -6544.0 |
| SMAD7 | -6539.0 |
| MBD6 | -6534.0 |
| RRAGA | -6528.0 |
| ANK3 | -6519.0 |
| CTSZ | -6514.0 |
| H2BC26 | -6508.0 |
| SEC23IP | -6448.0 |
| KCTD6 | -6437.0 |
| FUCA1 | -6418.0 |
| MYC | -6405.0 |
| COPS2 | -6398.0 |
| GOLM1 | -6393.0 |
| GFUS | -6383.0 |
| FCSK | -6355.0 |
| TEX101 | -6348.0 |
| PEX14 | -6333.0 |
| KNG1 | -6316.0 |
| SELENOS | -6311.0 |
| TADA3 | -6275.0 |
| RXRA | -6266.0 |
| NRN1L | -6229.0 |
| KAT2A | -6224.0 |
| MUC20 | -6215.0 |
| XRCC4 | -6211.0 |
| TPST2 | -6164.0 |
| PSMD14 | -6115.0 |
| MUC12 | -6112.0 |
| PPP6R1 | -6109.0 |
| SEC13 | -6075.0 |
| ALG3 | -6073.0 |
| RIPK2 | -6072.0 |
| FBXO27 | -6039.0 |
| NUP160 | -6038.0 |
| ACTR8 | -6029.0 |
| RARA | -6024.0 |
| IZUMO1R | -5963.0 |
| FOXK1 | -5946.0 |
| KLHL2 | -5902.0 |
| ADAMTS3 | -5896.0 |
| AGTPBP1 | -5881.0 |
| PSMA7 | -5868.0 |
| RNF168 | -5852.0 |
| THBS2 | -5846.0 |
| DCAF10 | -5801.0 |
| EDEM1 | -5797.0 |
| MBD5 | -5776.0 |
| FGG | -5755.0 |
| MIA2 | -5738.0 |
| USP24 | -5718.0 |
| ANK2 | -5716.0 |
| TAB1 | -5712.0 |
| APP | -5711.0 |
| ALG1 | -5707.0 |
| FKBP8 | -5700.0 |
| AGBL3 | -5670.0 |
| PRKN | -5662.0 |
| TBC1D20 | -5622.0 |
| IL6 | -5617.0 |
| MAN1A1 | -5580.0 |
| RAB4A | -5571.0 |
| NR1H4 | -5556.0 |
| POM121 | -5529.0 |
| FBXW7 | -5521.0 |
| RAB24 | -5500.0 |
| PPARA | -5445.0 |
| SPARCL1 | -5443.0 |
| OTULIN | -5424.0 |
| DCAF4 | -5422.0 |
| COG5 | -5420.0 |
| USP47 | -5403.0 |
| BABAM1 | -5363.0 |
| ADAMTS15 | -5359.0 |
| ASB6 | -5351.0 |
| SPTBN4 | -5317.0 |
| LY6D | -5293.0 |
| TTLL12 | -5240.0 |
| SPTAN1 | -5203.0 |
| USP22 | -5201.0 |
| TRAPPC3 | -5188.0 |
| AURKB | -5178.0 |
| ARFGAP3 | -5173.0 |
| PSMD7 | -5158.0 |
| TTL | -5137.0 |
| SKP2 | -5131.0 |
| FBXW9 | -5128.0 |
| NUP107 | -5114.0 |
| STX17 | -5083.0 |
| ST6GALNAC4 | -5058.0 |
| RAB6A | -5055.0 |
| RNF144A | -5045.0 |
| UBE2B | -5041.0 |
| MGAT4C | -5039.0 |
| GORASP1 | -5038.0 |
| NRN1 | -4999.0 |
| CAMKMT | -4984.0 |
| TNKS | -4979.0 |
| RNF2 | -4971.0 |
| INO80E | -4929.0 |
| INO80D | -4919.0 |
| RNF40 | -4910.0 |
| SUMO3 | -4903.0 |
| BARD1 | -4901.0 |
| TP53BP1 | -4896.0 |
| SCFD1 | -4886.0 |
| USP13 | -4884.0 |
| RAB13 | -4866.0 |
| NFRKB | -4865.0 |
| GALNT17 | -4851.0 |
| GALNT12 | -4850.0 |
| GALNT11 | -4842.0 |
| ETFBKMT | -4836.0 |
| PIAS3 | -4835.0 |
| NAPB | -4820.0 |
| NUP205 | -4807.0 |
| HGS | -4795.0 |
| JOSD2 | -4781.0 |
| MGAT2 | -4773.5 |
| KLHL20 | -4769.0 |
| ADAMTS20 | -4760.0 |
| UBE2R2 | -4758.0 |
| FBXO2 | -4755.0 |
| STT3A | -4752.0 |
| PSMD8 | -4743.0 |
| PPARGC1A | -4736.0 |
| NUB1 | -4735.0 |
| COPB1 | -4689.0 |
| CBX5 | -4623.0 |
| MDM4 | -4614.0 |
| LMAN2L | -4599.0 |
| INO80C | -4596.0 |
| BRCA1 | -4551.0 |
| HDAC7 | -4547.0 |
| F10 | -4540.0 |
| CANX | -4533.0 |
| TRIM13 | -4529.0 |
| ITIH2 | -4514.0 |
| SEC16B | -4492.0 |
| KDM1B | -4486.0 |
| RAB40B | -4445.0 |
| F5 | -4425.0 |
| ARSB | -4422.0 |
| TNFAIP3 | -4408.0 |
| NOP58 | -4405.0 |
| RAB1B | -4395.0 |
| FOLR2 | -4389.0 |
| RTN4RL2 | -4380.0 |
| CNIH1 | -4379.0 |
| MVD | -4365.0 |
| NCOR2 | -4363.0 |
| FBXW12 | -4352.0 |
| PEX10 | -4349.0 |
| USP34 | -4300.0 |
| PIGB | -4296.0 |
| H2BC4 | -4293.0 |
| MDGA1 | -4292.0 |
| CDCA8 | -4251.0 |
| ADAMTS16 | -4242.0 |
| VCP | -4221.0 |
| ADAMTSL1 | -4220.0 |
| BLM | -4214.0 |
| ST3GAL1 | -4206.0 |
| WDR5 | -4199.0 |
| PSMD5 | -4189.0 |
| LY6H | -4184.0 |
| NUP188 | -4180.0 |
| HERC2 | -4168.0 |
| B4GALT4 | -4167.0 |
| TMEM115 | -4158.0 |
| H2BC11 | -4149.0 |
| PEX5 | -4144.0 |
| COMMD6 | -4135.0 |
| RAB37 | -4129.0 |
| RIPK1 | -4127.0 |
| NEURL2 | -4126.0 |
| GPS1 | -4125.0 |
| DCTN4 | -4079.0 |
| NUP214 | -4077.0 |
| TUBA1C | -4053.0 |
| H2BC9 | -4045.5 |
| OTOA | -4044.0 |
| SHISA5 | -4040.0 |
| MAVS | -4030.0 |
| H2AC7 | -4012.5 |
| H2BC7 | -4012.5 |
| TNC | -3992.0 |
| NR4A2 | -3985.0 |
| RAB18 | -3976.0 |
| UBC | -3960.0 |
| HNRNPC | -3937.0 |
| PSMD11 | -3936.0 |
| RAB31 | -3923.0 |
| DYNC1LI2 | -3917.0 |
| LARGE1 | -3904.0 |
| B4GAT1 | -3901.0 |
| RAD23B | -3896.0 |
| PSMB2 | -3889.0 |
| FBXO11 | -3872.0 |
| NTM | -3863.0 |
| DYNC1I2 | -3835.0 |
| ASB10 | -3832.0 |
| FBXL19 | -3826.0 |
| SEC24B | -3817.0 |
| KAT2B | -3769.0 |
| NFE2L2 | -3768.0 |
| ART4 | -3766.0 |
| USP21 | -3756.0 |
| NRIP1 | -3749.0 |
| CUL9 | -3737.0 |
| POMT2 | -3733.0 |
| PPARG | -3730.0 |
| DDOST | -3727.0 |
| POFUT2 | -3724.0 |
| GMPPA | -3710.0 |
| BTBD1 | -3699.0 |
| DCAF5 | -3695.0 |
| TTLL9 | -3671.0 |
| SUZ12 | -3639.0 |
| ALG11 | -3611.0 |
| HDAC2 | -3577.0 |
| ST8SIA2 | -3572.0 |
| TTLL4 | -3568.0 |
| PRSS23 | -3563.0 |
| USP42 | -3559.0 |
| UHRF2 | -3557.0 |
| TGFBR1 | -3555.0 |
| GALNT2 | -3552.0 |
| BECN1 | -3543.0 |
| ULBP2 | -3540.0 |
| RBBP5 | -3535.0 |
| ADAMTSL5 | -3531.0 |
| TUSC3 | -3527.0 |
| NUP58 | -3490.0 |
| NEU1 | -3479.0 |
| PSMA6 | -3468.0 |
| DCTN6 | -3463.0 |
| UBE2K | -3457.0 |
| PEX12 | -3424.0 |
| HDAC1 | -3422.0 |
| ARF3 | -3409.0 |
| CNTN5 | -3404.0 |
| PSMD9 | -3390.0 |
| DPH7 | -3383.0 |
| MDC1 | -3380.0 |
| INO80 | -3377.0 |
| RPS27A | -3374.0 |
| TTLL5 | -3368.0 |
| MBD1 | -3358.0 |
| ALG6 | -3309.0 |
| ADAMTS13 | -3304.0 |
| CKAP4 | -3302.0 |
| DPAGT1 | -3287.0 |
| IGFBP5 | -3286.0 |
| MARCHF6 | -3259.0 |
| GBF1 | -3251.0 |
| FBXO21 | -3221.0 |
| EID3 | -3198.0 |
| SSPOP | -3180.0 |
| CSNK1D | -3170.0 |
| MIA3 | -3155.0 |
| PIGL | -3154.0 |
| UBE2F | -3128.0 |
| UBE2Z | -3125.0 |
| AGBL2 | -3120.0 |
| NANS | -3116.0 |
| RELA | -3097.0 |
| COMMD8 | -3094.0 |
| UBE2C | -3089.0 |
| KLHL5 | -3086.0 |
| OTUB2 | -3080.0 |
| VCPKMT | -3076.0 |
| DCTN5 | -3071.0 |
| PSME4 | -3068.0 |
| HSP90B1 | -3056.0 |
| RAB5A | -3055.0 |
| SEC31A | -3054.0 |
| TDG | -3034.0 |
| CUL7 | -3027.0 |
| TTLL13 | -3023.0 |
| DCAF13 | -3012.0 |
| DDA1 | -3008.0 |
| GGCX | -3000.0 |
| ARFGAP2 | -2988.0 |
| H2AC17 | -2969.0 |
| RABGGTA | -2951.0 |
| COMMD9 | -2948.0 |
| PIGM | -2945.0 |
| ATXN7 | -2933.0 |
| FBXW10 | -2915.0 |
| OTUD7B | -2913.0 |
| MAN2A1 | -2893.0 |
| FBXL13 | -2884.0 |
| EPAS1 | -2883.0 |
| FBXL14 | -2881.0 |
| TTLL11 | -2872.0 |
| PTP4A2 | -2840.0 |
| VASH2 | -2837.0 |
| CHD3 | -2835.0 |
| MCRS1 | -2817.0 |
| NEGR1 | -2787.0 |
| WRN | -2701.0 |
| TPST1 | -2698.0 |
| FBXL5 | -2667.0 |
| ADAMTS2 | -2652.0 |
| COG1 | -2650.0 |
| FUOM | -2630.0 |
| CALU | -2624.0 |
| CTR9 | -2617.0 |
| TUBA3D | -2604.0 |
| CEACAM5 | -2598.0 |
| NSMCE2 | -2594.0 |
| CAPZA1 | -2585.0 |
| UBE2M | -2548.0 |
| LSAMP | -2540.0 |
| RAD52 | -2529.0 |
| SEC22C | -2499.0 |
| SMURF2 | -2453.0 |
| SPSB2 | -2445.0 |
| SYVN1 | -2433.0 |
| PSMC5 | -2407.0 |
| KDELR3 | -2396.0 |
| VNN2 | -2395.0 |
| GRIA1 | -2393.0 |
| NPM1 | -2390.0 |
| ALG9 | -2389.0 |
| BIRC5 | -2374.0 |
| RAB36 | -2362.0 |
| USP14 | -2360.0 |
| MUC7 | -2354.0 |
| CUL5 | -2334.0 |
| DPH3 | -2325.0 |
| NFKBIA | -2311.0 |
| TMEM129 | -2299.0 |
| MUC13 | -2295.0 |
| ASB3 | -2278.0 |
| H2BC1 | -2276.0 |
| LHB | -2264.0 |
| COG4 | -2248.0 |
| NUP62 | -2238.0 |
| SCMH1 | -2230.0 |
| TPR | -2191.0 |
| LMAN1 | -2167.0 |
| NSF | -2159.0 |
| NR5A2 | -2147.0 |
| DHDDS | -2139.0 |
| RNF139 | -2105.0 |
| WDR20 | -2053.0 |
| C4A | -2042.5 |
| WDR48 | -2033.0 |
| UAP1 | -2029.0 |
| PLAUR | -2012.0 |
| PSMA2 | -1982.0 |
| PIAS4 | -1981.0 |
| NGLY1 | -1980.0 |
| BTRC | -1967.0 |
| FOXL2 | -1961.0 |
| PHC2 | -1956.0 |
| CBX8 | -1937.0 |
| SPSB4 | -1887.0 |
| TOPORS | -1874.0 |
| RPA1 | -1871.0 |
| VWA1 | -1869.0 |
| CP | -1842.0 |
| COPS6 | -1833.0 |
| TFAP2A | -1823.0 |
| SERPINA1 | -1802.0 |
| KLHL25 | -1795.0 |
| H2AC25 | -1780.0 |
| PGM3 | -1779.0 |
| DOLK | -1777.0 |
| FBXL15 | -1767.0 |
| BIRC2 | -1766.0 |
| FBN1 | -1763.0 |
| H2AC16 | -1755.0 |
| CUL1 | -1737.0 |
| FBXO22 | -1717.0 |
| KLHL11 | -1709.0 |
| TAF10 | -1697.0 |
| SEC23A | -1691.0 |
| NOD2 | -1669.0 |
| CD59 | -1661.0 |
| GALNT7 | -1646.0 |
| USP10 | -1642.0 |
| KLHL3 | -1641.0 |
| MYSM1 | -1632.0 |
| IL33 | -1612.0 |
| PALB2 | -1611.0 |
| DYNC1I1 | -1599.0 |
| DCAF7 | -1598.0 |
| ARF1 | -1577.0 |
| ST3GAL2 | -1574.0 |
| TECTA | -1571.0 |
| THSD7A | -1561.0 |
| CCNF | -1558.0 |
| RCN1 | -1542.0 |
| ST6GALNAC2 | -1541.0 |
| FBXO31 | -1492.0 |
| USP37 | -1467.0 |
| RAB39A | -1434.0 |
| AURKA | -1406.0 |
| ARSJ | -1402.0 |
| COMMD1 | -1386.0 |
| SP3 | -1356.0 |
| H4C9 | -1311.0 |
| TRIM27 | -1294.0 |
| ADAMTS12 | -1293.0 |
| CAND1 | -1292.0 |
| MAT2B | -1284.0 |
| H2BC8 | -1280.0 |
| ARFGAP1 | -1266.0 |
| ERCC8 | -1263.0 |
| H2BC3 | -1244.0 |
| PRKCSH | -1237.0 |
| RAB22A | -1235.0 |
| COMMD5 | -1172.0 |
| RAB42 | -1171.0 |
| SEMA5A | -1165.0 |
| DYNC1H1 | -1161.0 |
| WDTC1 | -1142.0 |
| UCHL5 | -1138.0 |
| USP15 | -1120.0 |
| B3GNTL1 | -1113.0 |
| FBXL20 | -1069.0 |
| ANK1 | -1061.0 |
| APOL1 | -1035.0 |
| CAPZB | -1025.0 |
| UBE2T | -1013.0 |
| PIGG | -1007.0 |
| EEF1AKMT2 | -1003.0 |
| DERL1 | -980.0 |
| GMDS | -976.0 |
| UBE2D3 | -967.0 |
| OPCML | -959.0 |
| CHST10 | -920.0 |
| RAB2B | -914.0 |
| SMC5 | -907.0 |
| ARSI | -890.0 |
| CUL2 | -848.0 |
| FUT8 | -847.0 |
| USP18 | -834.0 |
| FBXO44 | -824.0 |
| STAMBP | -822.0 |
| STX5 | -802.0 |
| COPS7A | -756.0 |
| H4C12 | -743.0 |
| SEC24A | -669.0 |
| L3MBTL2 | -668.0 |
| FBXW11 | -659.0 |
| MFGE8 | -655.0 |
| PSMB1 | -649.0 |
| CHST4 | -647.0 |
| TUBB4B | -641.0 |
| UIMC1 | -604.0 |
| PARK7 | -601.0 |
| UBE2G2 | -598.0 |
| TMED10 | -585.0 |
| NFKB2 | -568.0 |
| ING2 | -539.0 |
| COG8 | -528.0 |
| ART3 | -524.0 |
| TGFA | -493.0 |
| DCUN1D2 | -489.0 |
| TPGS2 | -484.0 |
| MUC4 | -482.0 |
| SEC22B | -481.0 |
| PROC | -423.0 |
| H2BC17 | -400.0 |
| INCENP | -397.0 |
| ASGR2 | -373.0 |
| CNTN3 | -363.0 |
| TOMM20 | -353.0 |
| PSMC1 | -332.0 |
| NAGK | -325.0 |
| ADAM10 | -322.0 |
| KIN | -307.0 |
| GALNTL6 | -288.0 |
| DYNC1LI1 | -283.0 |
| SMAD2 | -263.0 |
| HNRNPK | -257.0 |
| THRA | -255.0 |
| SMAD4 | -254.0 |
| DDB1 | -236.0 |
| PSMD13 | -227.0 |
| EEF1A1 | -169.0 |
| TPGS1 | -165.0 |
| RUVBL1 | -127.0 |
| TRAPPC2L | -105.0 |
| ALG12 | -97.0 |
| ABRAXAS1 | -81.0 |
| SENP1 | -75.0 |
| EDEM3 | -39.0 |
| HIF1A | -30.0 |
| TGFBR2 | -10.0 |
| SPTBN2 | -2.0 |
| FEM1C | 0.0 |
| PSMC6 | 25.0 |
| ALG5 | 28.0 |
| LAMC1 | 32.0 |
| RNF146 | 34.0 |
| ST8SIA5 | 35.0 |
| USP3 | 43.0 |
| CREBBP | 66.0 |
| THSD4 | 73.0 |
| PIGK | 85.0 |
| LEO1 | 101.0 |
| CD109 | 125.0 |
| SUDS3 | 131.0 |
| PSMD6 | 166.0 |
| FN3K | 199.0 |
| PROZ | 202.0 |
| NCOA1 | 220.0 |
| MUC5AC | 225.0 |
| GOSR2 | 228.0 |
| SERPINC1 | 238.0 |
| MTA1 | 276.0 |
| CCNA1 | 300.0 |
| RHOT1 | 312.0 |
| RING1 | 314.0 |
| TUBA1A | 318.0 |
| GOLGB1 | 347.0 |
| PSMF1 | 351.0 |
| SIN3A | 397.0 |
| TFAP2B | 401.0 |
| BIRC3 | 435.0 |
| PSMD2 | 438.0 |
| UBE2D1 | 455.0 |
| ADAMTS8 | 457.0 |
| RNF185 | 487.0 |
| PML | 489.0 |
| SLC35A1 | 530.0 |
| RTN4RL1 | 532.0 |
| H2BC5 | 561.0 |
| TF | 580.0 |
| TUBB3 | 582.0 |
| ALG8 | 593.0 |
| NUP133 | 603.0 |
| ADAMTS9 | 614.0 |
| IFIH1 | 615.0 |
| SUMF1 | 628.0 |
| H2BC12 | 630.0 |
| ATXN3 | 655.0 |
| CTSA | 663.0 |
| QSOX1 | 666.0 |
| SQSTM1 | 674.0 |
| CCP110 | 687.0 |
| FBXO7 | 727.0 |
| HRC | 733.0 |
| ADRB2 | 768.0 |
| ASB17 | 822.0 |
| FSTL3 | 827.0 |
| PIGC | 830.0 |
| LMAN2 | 831.0 |
| USP28 | 834.0 |
| PSMB10 | 869.0 |
| MITF | 921.0 |
| NTNG2 | 935.0 |
| ST6GALNAC3 | 959.0 |
| FUCA2 | 967.0 |
| TOP2B | 972.0 |
| ACTR10 | 974.0 |
| PGR | 976.0 |
| SPP1 | 985.0 |
| RWDD3 | 1000.0 |
| ST8SIA4 | 1012.0 |
| FBXL7 | 1026.0 |
| LTBP1 | 1043.0 |
| ACTL6A | 1044.0 |
| DDB2 | 1053.0 |
| RTF1 | 1068.0 |
| BMP4 | 1073.0 |
| TRAPPC9 | 1075.0 |
| UBE2V2 | 1082.0 |
| ASB15 | 1096.0 |
| PSMC2 | 1115.0 |
| PSMD1 | 1119.0 |
| XPC | 1155.0 |
| GALNT10 | 1156.0 |
| PIGN | 1169.0 |
| NEDD8 | 1171.0 |
| LYPD6B | 1210.0 |
| ASB13 | 1225.0 |
| UCHL3 | 1241.0 |
| TNIP3 | 1252.0 |
| B3GALNT2 | 1257.0 |
| GALNT5 | 1301.0 |
| SP100 | 1305.0 |
| VASH1 | 1330.0 |
| SPTBN1 | 1334.0 |
| TRRAP | 1340.0 |
| SHPRH | 1344.0 |
| PIGT | 1354.0 |
| EDEM2 | 1361.0 |
| GALNT13 | 1391.0 |
| PSCA | 1398.0 |
| H2BC10 | 1402.0 |
| DPM2 | 1407.0 |
| GALNT9 | 1408.0 |
| NUCB1 | 1424.0 |
| ARSG | 1452.0 |
| PIGH | 1461.0 |
| ADAMTSL3 | 1463.0 |
| MDM2 | 1514.0 |
| RNF135 | 1519.0 |
| DCUN1D3 | 1531.0 |
| MPDU1 | 1550.0 |
| ZBTB16 | 1557.0 |
| ADAMTSL2 | 1571.0 |
| DNMT3A | 1574.0 |
| DAXX | 1579.0 |
| LYPD1 | 1586.0 |
| LY6G6C | 1604.0 |
| NLRP3 | 1626.0 |
| MUC16 | 1657.0 |
| PIAS2 | 1661.0 |
| BABAM2 | 1699.0 |
| STAG1 | 1716.0 |
| TUBA1B | 1730.0 |
| USP20 | 1731.0 |
| LAMB1 | 1736.0 |
| CSF1 | 1739.0 |
| H4C3 | 1748.0 |
| STC2 | 1758.0 |
| TULP4 | 1781.0 |
| RAB44 | 1783.0 |
| NUP88 | 1817.0 |
| SEMA5B | 1819.0 |
| MRTFA | 1821.0 |
| NDC1 | 1824.0 |
| PTEN | 1836.0 |
| FBXO30 | 1837.0 |
| RAB1A | 1846.0 |
| TECTB | 1856.0 |
| TRAPPC10 | 1857.0 |
| LARGE2 | 1879.0 |
| METTL21A | 1945.0 |
| UCHL1 | 1950.0 |
| PSME2 | 1954.0 |
| ARF4 | 1970.0 |
| WSB1 | 1990.0 |
| MUL1 | 2005.0 |
| NPLOC4 | 2017.0 |
| UBE2L3 | 2027.0 |
| ASB14 | 2057.0 |
| USP30 | 2076.0 |
| NR2C1 | 2122.0 |
| FAM20C | 2147.0 |
| RORA | 2153.0 |
| EEF2 | 2157.0 |
| B3GNT5 | 2164.0 |
| HIPK2 | 2166.0 |
| AGBL1 | 2186.0 |
| LAMB2 | 2215.0 |
| WFS1 | 2256.0 |
| BET1L | 2274.0 |
| IDE | 2291.0 |
| RAB8B | 2313.0 |
| DNAJC24 | 2324.0 |
| DERL2 | 2326.0 |
| USP48 | 2335.0 |
| CBX4 | 2344.0 |
| THRB | 2348.0 |
| H2AC18 | 2377.5 |
| H2AC19 | 2377.5 |
| NR5A1 | 2382.0 |
| ASB2 | 2410.0 |
| NUP42 | 2415.0 |
| MEN1 | 2422.0 |
| TRAPPC6B | 2427.0 |
| GFPT2 | 2468.0 |
| USP25 | 2475.0 |
| LYPD2 | 2488.0 |
| PSMD12 | 2494.0 |
| FBXL4 | 2504.0 |
| AGBL4 | 2517.0 |
| NUS1 | 2530.0 |
| HDAC4 | 2564.0 |
| COPZ2 | 2581.0 |
| H2AC4 | 2594.0 |
| NR3C1 | 2611.0 |
| H2AC20 | 2634.0 |
| ANO8 | 2637.0 |
| TRAPPC1 | 2657.0 |
| MGAT3 | 2664.0 |
| ARRB1 | 2670.0 |
| USP44 | 2691.0 |
| ZNF350 | 2714.0 |
| UBD | 2750.0 |
| F2 | 2752.0 |
| SAR1B | 2783.0 |
| DPH6 | 2786.0 |
| FN1 | 2815.0 |
| RAB5C | 2816.0 |
| ARCN1 | 2823.0 |
| THBS1 | 2830.0 |
| KLHL9 | 2843.0 |
| RNF123 | 2854.0 |
| GALNTL5 | 2874.0 |
| TRAPPC4 | 2887.0 |
| UFD1 | 2888.0 |
| ST6GALNAC5 | 2893.0 |
| GANAB | 2913.0 |
| DCAF6 | 2918.0 |
| USP33 | 2932.0 |
| MGAT4A | 2942.0 |
| COPG2 | 2943.0 |
| RNF20 | 2955.0 |
| B3GLCT | 2957.0 |
| ADAMTS19 | 3001.0 |
| ARRB2 | 3002.0 |
| RAB10 | 3030.0 |
| SPON1 | 3068.0 |
| CDH2 | 3076.0 |
| GAN | 3119.0 |
| NUP93 | 3123.0 |
| TUBB2A | 3132.0 |
| MAN1A2 | 3134.0 |
| MUC5B | 3137.0 |
| B3GNT8 | 3145.0 |
| CNTN4 | 3152.0 |
| PCNA | 3188.0 |
| USP7 | 3204.0 |
| CTBP1 | 3209.0 |
| SMAD1 | 3210.0 |
| KBTBD6 | 3229.0 |
| GCNT4 | 3256.0 |
| SEH1L | 3261.0 |
| RAB15 | 3276.0 |
| FEM1A | 3318.0 |
| CDC73 | 3340.0 |
| CDC20 | 3349.0 |
| SDC2 | 3351.0 |
| TOP2A | 3355.0 |
| DHPS | 3398.0 |
| RAE1 | 3415.0 |
| BET1 | 3427.0 |
| ALB | 3438.0 |
| OTUD3 | 3486.0 |
| VCAN | 3493.0 |
| HLTF | 3496.0 |
| MELTF | 3528.0 |
| GLB1 | 3562.0 |
| HIC1 | 3570.0 |
| PSMA8 | 3597.0 |
| COMMD2 | 3611.0 |
| TMED3 | 3623.0 |
| CUL4A | 3629.0 |
| FBXW2 | 3630.0 |
| NUDT14 | 3641.0 |
| SCG3 | 3661.0 |
| PEX2 | 3676.0 |
| ESR1 | 3701.0 |
| THSD1 | 3712.0 |
| ALG2 | 3750.0 |
| EIF5A2 | 3762.0 |
| ST3GAL4 | 3763.0 |
| GCNT1 | 3788.0 |
| SEM1 | 3801.0 |
| SAE1 | 3810.0 |
| SEC24D | 3822.0 |
| CCN1 | 3842.0 |
| DCUN1D5 | 3848.0 |
| COPE | 3857.0 |
| TUBAL3 | 3868.0 |
| PAF1 | 3891.0 |
| COG3 | 3916.0 |
| UBXN7 | 3927.0 |
| MANEA | 3944.0 |
| ARSK | 3962.0 |
| ADAMTS6 | 3969.0 |
| PLET1 | 3974.0 |
| ENGASE | 3984.0 |
| DCUN1D4 | 3989.0 |
| ST6GAL1 | 4037.0 |
| RAB14 | 4054.0 |
| DNMT1 | 4074.0 |
| DDX17 | 4091.0 |
| BCL10 | 4105.0 |
| ALPI | 4108.0 |
| RAB5B | 4118.0 |
| COPS4 | 4123.0 |
| DCAF11 | 4162.0 |
| JOSD1 | 4170.0 |
| PSMB4 | 4183.0 |
| NR1H3 | 4188.0 |
| HSPA8 | 4201.0 |
| SEC16A | 4216.0 |
| USP8 | 4247.0 |
| FBXO41 | 4295.0 |
| A4GNT | 4314.0 |
| IGFBP7 | 4323.0 |
| SNX3 | 4337.0 |
| ADRM1 | 4342.0 |
| RIGI | 4352.0 |
| PSMD4 | 4365.0 |
| ST8SIA6 | 4376.0 |
| CALM1 | 4408.0 |
| FBXW5 | 4411.0 |
| LYPD3 | 4424.0 |
| TRAF6 | 4480.0 |
| IGFBP3 | 4499.0 |
| H2BC13 | 4513.0 |
| MUC1 | 4559.0 |
| H2AC8 | 4562.0 |
| UGGT1 | 4607.0 |
| SATB2 | 4636.0 |
| RAB6B | 4733.0 |
| RAB38 | 4735.0 |
| COPA | 4736.0 |
| CCNA2 | 4748.0 |
| GNPNAT1 | 4773.0 |
| EP300 | 4777.0 |
| UBE2D2 | 4781.0 |
| SKP1 | 4805.0 |
| SPSB3 | 4829.0 |
| ASGR1 | 4856.0 |
| RAB25 | 4858.0 |
| HIF3A | 4871.0 |
| ASB7 | 4873.0 |
| FBXL3 | 4875.0 |
| ALG14 | 4891.0 |
| ASXL2 | 4907.0 |
| MAN2A2 | 4938.0 |
| TFAP2C | 4981.0 |
| PHC1 | 5006.0 |
| NUP210 | 5007.0 |
| COG6 | 5046.0 |
| CHST8 | 5055.0 |
| TNKS2 | 5073.0 |
| ST3GAL6 | 5093.0 |
| POLB | 5096.0 |
| DCAF8 | 5097.0 |
| CDK1 | 5109.0 |
| USP16 | 5122.0 |
| UMOD | 5138.0 |
| H2BC6 | 5160.0 |
| RAET1G | 5179.0 |
| FPGT | 5199.0 |
| ARSA | 5204.0 |
| PRKDC | 5209.0 |
| NSMCE1 | 5243.0 |
| MAN1B1 | 5305.0 |
| H4C2 | 5307.0 |
| USP4 | 5329.0 |
| TUBB1 | 5346.0 |
| NAPG | 5432.0 |
| FOXK2 | 5456.0 |
| SEC24C | 5488.0 |
| GALNT14 | 5497.0 |
| TMEM132A | 5512.0 |
| ALPL | 5518.0 |
| AFP | 5534.0 |
| DPH1 | 5544.0 |
| DDX5 | 5571.0 |
| NSMCE4A | 5574.0 |
| PSMA4 | 5588.0 |
| RAB27B | 5590.0 |
| PTRH2 | 5592.0 |
| H2AC1 | 5593.0 |
| PSMB5 | 5606.0 |
| TFPT | 5608.0 |
| RAB27A | 5652.0 |
| POMGNT1 | 5676.0 |
| POMGNT2 | 5685.0 |
| VGF | 5695.0 |
| PHC3 | 5709.0 |
| RAET1L | 5721.0 |
| COPS7B | 5746.0 |
| ADAMTS18 | 5749.0 |
| PIGO | 5772.0 |
| DTL | 5775.0 |
| PIGF | 5781.0 |
| MEPE | 5814.0 |
| MUC21 | 5834.0 |
| USO1 | 5838.0 |
| RFT1 | 5840.0 |
| H4C6 | 5848.0 |
| PCSK9 | 5907.0 |
| TRAF3 | 5929.0 |
| MGAT1 | 5941.0 |
| VDR | 5955.0 |
| GPIHBP1 | 5959.0 |
| SEL1L | 5990.0 |
| FBXO6 | 5996.0 |
| KLHL21 | 6006.0 |
| FBXL22 | 6010.0 |
| ACTB | 6012.0 |
| UBA3 | 6013.0 |
| FURIN | 6044.0 |
| RECK | 6081.0 |
| TADA2B | 6108.0 |
| VCPIP1 | 6121.0 |
| ELOC | 6137.0 |
| PMM2 | 6146.0 |
| COMMD10 | 6157.0 |
| SPSB1 | 6186.0 |
| TUBA3C | 6217.0 |
| DCTN1 | 6219.0 |
| GALNT16 | 6246.0 |
| TP53 | 6303.0 |
| GMPPB | 6314.0 |
| RAB33B | 6369.0 |
| TRIM28 | 6387.0 |
| H4C5 | 6393.0 |
| ADAMTS4 | 6403.0 |
| RNF152 | 6406.0 |
| RAB32 | 6447.0 |
| COL7A1 | 6457.0 |
| PSMB3 | 6513.0 |
| PSMA1 | 6519.0 |
| LY6K | 6529.0 |
| RNF181 | 6530.0 |
| H4C4 | 6557.0 |
| ADAMTSL4 | 6577.0 |
| LY6G6D | 6595.0 |
| RPS2 | 6614.0 |
| TRAPPC5 | 6630.0 |
| NUP54 | 6655.0 |
| ST3GAL5 | 6656.0 |
| RAB17 | 6689.0 |
| DCTN3 | 6735.0 |
| NPL | 6769.0 |
| H4C16 | 6840.0 |
| PSMD3 | 6889.0 |
| OS9 | 6899.0 |
| FAM20A | 6909.0 |
| PENK | 6920.0 |
| ST6GAL2 | 6982.0 |
| RAB8A | 7033.0 |
| ASB18 | 7070.0 |
| FBXL8 | 7088.0 |
| PEX13 | 7096.0 |
| CD55 | 7097.0 |
| ASB4 | 7099.0 |
| USP2 | 7131.0 |
| TNIP1 | 7167.0 |
| TTLL10 | 7177.0 |
| NTNG1 | 7185.0 |
| UBE2I | 7197.0 |
| GCNT3 | 7205.0 |
| SMAD3 | 7259.0 |
| CTSC | 7289.0 |
| UGGT2 | 7301.0 |
| DPH2 | 7305.0 |
| NANP | 7330.0 |
| FGF23 | 7346.0 |
| LGALS1 | 7373.0 |
| MUC6 | 7384.0 |
| PCGF2 | 7396.0 |
| YOD1 | 7403.0 |
| DOHH | 7413.0 |
| KCTD7 | 7432.0 |
| CHGB | 7438.0 |
| PPP6C | 7462.0 |
| PIGW | 7465.0 |
| RAB3C | 7494.0 |
| SCG2 | 7497.0 |
| FBXL16 | 7509.0 |
| SPTA1 | 7519.0 |
| TMED7 | 7548.0 |
| H4C8 | 7603.0 |
| TUBB6 | 7617.0 |
| ELOB | 7624.0 |
| H4C13 | 7627.0 |
| H2AC11 | 7678.0 |
| ST8SIA3 | 7703.0 |
| GALNT3 | 7712.0 |
| POMT1 | 7742.0 |
| MGAT5 | 7773.0 |
| ALG10 | 7809.0 |
| MSLN | 7819.0 |
| CST3 | 7834.0 |
| P4HB | 7836.0 |
| H2BC15 | 7838.0 |
| OBSL1 | 7846.0 |
| AMDHD2 | 7873.0 |
| SPTB | 7879.0 |
| UBA52 | 7910.0 |
| FSTL1 | 7926.0 |
| APOB | 7935.0 |
| ICMT | 7947.0 |
| SPON2 | 7977.0 |
| PSMA3 | 7987.0 |
| CDC34 | 7992.0 |
| RAB35 | 7994.0 |
| GALNT18 | 7996.0 |
| DCAF16 | 8014.0 |
| TUBB2B | 8061.0 |
| AXIN1 | 8077.0 |
| PSMC3 | 8087.0 |
| NEU4 | 8150.0 |
| PRSS21 | 8155.0 |
| NUP43 | 8160.0 |
| FBXO17 | 8163.0 |
| H2BC21 | 8214.0 |
| AGBL5 | 8219.0 |
| CGA | 8227.0 |
| SERPINA10 | 8255.0 |
| NUP35 | 8282.0 |
| B3GNT6 | 8283.0 |
| SPTBN5 | 8293.0 |
| SBSPON | 8303.0 |
| MXRA8 | 8319.0 |
| MDGA2 | 8327.0 |
| EIF5A | 8343.0 |
| INS | 8351.0 |
| POM121C | 8393.0 |
| TUBA3E | 8431.0 |
| ALG10B | 8501.0 |
| SKIC8 | 8536.0 |
| NOTUM | 8563.0 |
| F7 | 8629.0 |
| TUBA8 | 8640.0 |
| NR1I2 | 8654.0 |
| OTUD7A | 8668.0 |
| DYNLL2 | 8677.0 |
| APLP2 | 8708.0 |
| B4GALNT2 | 8717.0 |
| SATB1 | 8734.0 |
| H4C11 | 8737.0 |
| CFTR | 8755.0 |
| CNIH3 | 8778.0 |
| C3 | 8800.0 |
| NUP85 | 8816.0 |
| B3GNT9 | 8836.0 |
| RAB20 | 8841.0 |
| DMP1 | 8864.0 |
| IKBKE | 8868.0 |
| DAD1 | 8886.0 |
| RAB29 | 8942.0 |
| ALPG | 8976.0 |
| PREB | 9078.0 |
| H2AC12 | 9109.0 |
| BGLAP | 9115.0 |
| ADAMTS14 | 9138.0 |
| SRD5A3 | 9148.0 |
| B4GALT6 | 9163.0 |
| H2AC13 | 9173.0 |
| ADAMTS5 | 9193.0 |
| H2AC21 | 9249.0 |
| NSMCE3 | 9260.0 |
| SOCS6 | 9276.0 |
| H2AC15 | 9298.0 |
| ARF5 | 9302.0 |
| FGA | 9347.0 |
| VNN1 | 9418.0 |
| PARP1 | 9425.0 |
| B3GNT7 | 9449.0 |
| RNF5 | 9454.0 |
| ADAMTS1 | 9554.0 |
| CCDC8 | 9701.0 |
| CHML | 9731.0 |
| LYPD8 | 9968.0 |
| SPRN | 10033.0 |
REACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF
| 200 | |
|---|---|
| set | REACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF |
| setSize | 53 |
| pANOVA | 0.0012 |
| s.dist | -0.257 |
| p.adjustANOVA | 0.171 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| HMGCR | -10938 |
| INSIG2 | -10393 |
| MBTPS1 | -9589 |
| SCD | -9415 |
| HMGCS1 | -9158 |
| NCOA2 | -8959 |
| SQLE | -8695 |
| CARM1 | -8567 |
| CHD9 | -8549 |
| MTF1 | -8255 |
| PMVK | -8094 |
| SP1 | -7936 |
| TM7SF2 | -7337 |
| SREBF2 | -6976 |
| ACACA | -6898 |
| RAN | -6893 |
| SMARCD3 | -6859 |
| FDPS | -6447 |
| RXRA | -6266 |
| ELOVL6 | -6198 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| HMGCR | -10938 |
| INSIG2 | -10393 |
| MBTPS1 | -9589 |
| SCD | -9415 |
| HMGCS1 | -9158 |
| NCOA2 | -8959 |
| SQLE | -8695 |
| CARM1 | -8567 |
| CHD9 | -8549 |
| MTF1 | -8255 |
| PMVK | -8094 |
| SP1 | -7936 |
| TM7SF2 | -7337 |
| SREBF2 | -6976 |
| ACACA | -6898 |
| RAN | -6893 |
| SMARCD3 | -6859 |
| FDPS | -6447 |
| RXRA | -6266 |
| ELOVL6 | -6198 |
| NCOA6 | -6009 |
| PPARA | -5445 |
| INSIG1 | -4468 |
| MVD | -4365 |
| MVK | -4328 |
| SEC24B | -3817 |
| FASN | -3711 |
| TGS1 | -3648 |
| NFYA | -3313 |
| KPNB1 | -3143 |
| ACACB | -3115 |
| SCAP | -2760 |
| IDI1 | -2486 |
| SC5D | -2232 |
| GPAM | -1711 |
| SEC23A | -1691 |
| CYP51A1 | -1296 |
| MED1 | -750 |
| SEC24A | -669 |
| GGPS1 | -429 |
| LSS | -256 |
| CREBBP | 66 |
| NCOA1 | 220 |
| SREBF1 | 550 |
| FDFT1 | 910 |
| TBL1XR1 | 1614 |
| NFYC | 2000 |
| DHCR7 | 2277 |
| SAR1B | 2783 |
| HELZ2 | 3253 |
| SEC24D | 3822 |
| NFYB | 5323 |
| SEC24C | 5488 |
REACTOME_FATTY_ACID_METABOLISM
| 1342 | |
|---|---|
| set | REACTOME_FATTY_ACID_METABOLISM |
| setSize | 170 |
| pANOVA | 0.00125 |
| s.dist | -0.143 |
| p.adjustANOVA | 0.171 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| ACOT6 | -11697 |
| CYP4F2 | -11632 |
| THEM5 | -11617 |
| GPX2 | -11510 |
| HSD17B3 | -11344 |
| DPEP3 | -11300 |
| CYP2J2 | -11290 |
| PTGDS | -11284 |
| DPEP1 | -11258 |
| CYP4F3 | -11093 |
| ACADVL | -11031 |
| MORC2 | -10928 |
| PCCB | -10506 |
| TECRL | -10452 |
| ELOVL1 | -10446 |
| MECR | -10406 |
| ALOX15 | -10399 |
| ACOT13 | -10357 |
| ACAD10 | -10215 |
| ACOT4 | -10190 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ACOT6 | -11697 |
| CYP4F2 | -11632 |
| THEM5 | -11617 |
| GPX2 | -11510 |
| HSD17B3 | -11344 |
| DPEP3 | -11300 |
| CYP2J2 | -11290 |
| PTGDS | -11284 |
| DPEP1 | -11258 |
| CYP4F3 | -11093 |
| ACADVL | -11031 |
| MORC2 | -10928 |
| PCCB | -10506 |
| TECRL | -10452 |
| ELOVL1 | -10446 |
| MECR | -10406 |
| ALOX15 | -10399 |
| ACOT13 | -10357 |
| ACAD10 | -10215 |
| ACOT4 | -10190 |
| PECR | -10056 |
| HSD17B12 | -10041 |
| NDUFAB1 | -9989 |
| ACOX2 | -9831 |
| ELOVL4 | -9595 |
| AMACR | -9444 |
| SCD | -9415 |
| CYP2C8 | -9343 |
| PHYH | -9282 |
| SLC25A17 | -9219 |
| CYP2C19 | -8891 |
| CYP4F8 | -8851 |
| PPT1 | -8608 |
| CYP4F22 | -8484 |
| HSD17B8 | -8234 |
| DBI | -8207 |
| ECI1 | -7678 |
| ALOX12B | -7436 |
| PPT2 | -7371 |
| HAO2 | -7306 |
| PRXL2B | -7295 |
| TECR | -7176 |
| CPT1B | -7157 |
| ACOT2 | -7056 |
| ACADL | -7015 |
| ACACA | -6898 |
| SLC25A1 | -6749 |
| FADS2 | -6620 |
| CRAT | -6563 |
| ACOT7 | -6554 |
| GGT5 | -6531 |
| NUDT7 | -6500 |
| ACBD7 | -6326 |
| MLYCD | -6285 |
| RXRA | -6266 |
| ELOVL6 | -6198 |
| ALDH3A2 | -6135 |
| SLC27A3 | -5895 |
| MMAA | -5771 |
| FADS1 | -5655 |
| DECR2 | -5649 |
| ABCC1 | -5551 |
| CROT | -5409 |
| ACLY | -5064 |
| PTGS2 | -5030 |
| ACSM3 | -4853 |
| ACOT11 | -4789 |
| ELOVL5 | -4608 |
| HPGDS | -4210 |
| CYP4B1 | -4065 |
| OLAH | -3760 |
| PCTP | -3745 |
| PTGES | -3734 |
| FASN | -3711 |
| ECI2 | -3660 |
| PTGES3 | -3496 |
| ACSL5 | -3431 |
| ACSBG1 | -3415 |
| CBR4 | -3341 |
| PTGR2 | -3268 |
| HACD3 | -3261 |
| ACSL3 | -3216 |
| CPT2 | -3212 |
| ACACB | -3115 |
| GGT1 | -3063 |
| ACADS | -3052 |
| EHHADH | -2978 |
| HACD2 | -2887 |
| CPT1A | -2815 |
| ACBD5 | -2784 |
| CYP1A1 | -2769 |
| MCEE | -2728 |
| HADH | -2716 |
| MAPKAPK2 | -2537 |
| FAAH | -2434 |
| EPHX2 | -2386 |
| HACD1 | -2370 |
| MMUT | -2216 |
| GPX4 | -2172 |
| AKR1C3 | -2123 |
| ACOX1 | -2027 |
| NUDT19 | -1885 |
| SLC22A5 | -1815 |
| ACOT8 | -1751 |
| CYP2U1 | -1396 |
| HSD17B4 | -1049 |
| CYP2C9 | -844 |
| CYP1B1 | -803 |
| HPGD | -461 |
| ALOX5 | -349 |
| ACAA2 | -245 |
| HACL1 | -133 |
| ACAD11 | -79 |
| ACSL1 | 167 |
| PPARD | 379 |
| PTGS1 | 444 |
| CYP1A2 | 469 |
| ACBD6 | 569 |
| ECHS1 | 848 |
| PRKAG2 | 962 |
| ALOX5AP | 1128 |
| THEM4 | 1234 |
| PON2 | 1621 |
| MCAT | 1664 |
| DPEP2 | 2333 |
| SLC25A20 | 2505 |
| PRKAB2 | 2720 |
| ACBD4 | 2733 |
| ELOVL2 | 3085 |
| ALOX12 | 3155 |
| ACADM | 3294 |
| ACSF2 | 3480 |
| ACSL6 | 3719 |
| PTGR1 | 4002 |
| ACOX3 | 4017 |
| ACOXL | 4141 |
| DECR1 | 4147 |
| SCD5 | 4150 |
| PCCA | 4285 |
| TBXAS1 | 4343 |
| SCP2 | 4410 |
| ACSF3 | 4434 |
| ALOXE3 | 4727 |
| CYP4F11 | 4880 |
| ACSM6 | 4889 |
| PON1 | 4937 |
| ALOX15B | 5150 |
| HADHA | 5263 |
| LTC4S | 5320 |
| HADHB | 5478 |
| LTA4H | 5548 |
| ELOVL3 | 5914 |
| PRKAA2 | 6287 |
| PLA2G4A | 6436 |
| ACSBG2 | 6784 |
| THRSP | 6892 |
| ACAA1 | 6926 |
| PON3 | 6943 |
| CYP4A11 | 7179 |
| CBR1 | 7567 |
| GPX1 | 7792 |
| ELOVL7 | 8469 |
| HACD4 | 8698 |
| ACOT1 | 8822 |
| PTGES2 | 8823 |
| PTGIS | 8846 |
| SLC27A2 | 9377 |
| CYP4A22 | 9614 |
| ACOT12 | 9624 |
| CYP8B1 | 9812 |
REACTOME_GLOBAL_GENOME_NUCLEOTIDE_EXCISION_REPAIR_GG_NER
| 1022 | |
|---|---|
| set | REACTOME_GLOBAL_GENOME_NUCLEOTIDE_EXCISION_REPAIR_GG_NER |
| setSize | 81 |
| pANOVA | 0.00136 |
| s.dist | -0.206 |
| p.adjustANOVA | 0.172 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| SUMO2 | -11339 |
| POLD4 | -11002 |
| SUMO1 | -10728 |
| RAD23A | -10503 |
| POLE2 | -10034 |
| COPS8 | -9834 |
| ERCC1 | -9751 |
| RBX1 | -9464 |
| XPA | -9331 |
| UBB | -8790 |
| ERCC2 | -8731 |
| RPA2 | -8723 |
| ACTR5 | -8153 |
| UBE2N | -8046 |
| YY1 | -8000 |
| CDK7 | -7755 |
| COPS3 | -7685 |
| INO80B | -7580 |
| POLE4 | -7226 |
| COPS5 | -7224 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SUMO2 | -11339 |
| POLD4 | -11002 |
| SUMO1 | -10728 |
| RAD23A | -10503 |
| POLE2 | -10034 |
| COPS8 | -9834 |
| ERCC1 | -9751 |
| RBX1 | -9464 |
| XPA | -9331 |
| UBB | -8790 |
| ERCC2 | -8731 |
| RPA2 | -8723 |
| ACTR5 | -8153 |
| UBE2N | -8046 |
| YY1 | -8000 |
| CDK7 | -7755 |
| COPS3 | -7685 |
| INO80B | -7580 |
| POLE4 | -7226 |
| COPS5 | -7224 |
| CHD1L | -7214 |
| XRCC1 | -7045 |
| POLE | -6849 |
| ERCC5 | -6626 |
| PIAS1 | -6572 |
| COPS2 | -6398 |
| RFC1 | -6180 |
| ACTR8 | -6029 |
| POLD2 | -5763 |
| LIG1 | -5520 |
| POLK | -5451 |
| POLD3 | -5248 |
| PARP2 | -5213 |
| RFC5 | -4967 |
| INO80E | -4929 |
| INO80D | -4919 |
| GTF2H4 | -4904 |
| SUMO3 | -4903 |
| NFRKB | -4865 |
| PIAS3 | -4835 |
| GTF2H3 | -4677 |
| INO80C | -4596 |
| GPS1 | -4125 |
| UBC | -3960 |
| RAD23B | -3896 |
| INO80 | -3377 |
| RPS27A | -3374 |
| ERCC4 | -3337 |
| GTF2H5 | -3048 |
| MCRS1 | -2817 |
| RPA3 | -2234 |
| RPA1 | -1871 |
| COPS6 | -1833 |
| USP45 | -1038 |
| COPS7A | -756 |
| POLE3 | -631 |
| DDB1 | -236 |
| RUVBL1 | -127 |
| RFC3 | 262 |
| RFC2 | 597 |
| ACTL6A | 1044 |
| DDB2 | 1053 |
| UBE2V2 | 1082 |
| XPC | 1155 |
| CCNH | 1898 |
| POLD1 | 1996 |
| ERCC3 | 3005 |
| PCNA | 3188 |
| CUL4A | 3629 |
| LIG3 | 3968 |
| COPS4 | 4123 |
| RFC4 | 4373 |
| RNF111 | 5062 |
| MNAT1 | 5269 |
| TFPT | 5608 |
| COPS7B | 5746 |
| ACTB | 6012 |
| GTF2H1 | 6412 |
| UBE2I | 7197 |
| UBA52 | 7910 |
| PARP1 | 9425 |
REACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP
| 486 | |
|---|---|
| set | REACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP |
| setSize | 41 |
| pANOVA | 0.0016 |
| s.dist | -0.285 |
| p.adjustANOVA | 0.187 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| HMGCR | -10938 |
| SCD | -9415 |
| HMGCS1 | -9158 |
| NCOA2 | -8959 |
| SQLE | -8695 |
| CARM1 | -8567 |
| CHD9 | -8549 |
| MTF1 | -8255 |
| PMVK | -8094 |
| SP1 | -7936 |
| TM7SF2 | -7337 |
| SREBF2 | -6976 |
| ACACA | -6898 |
| SMARCD3 | -6859 |
| FDPS | -6447 |
| RXRA | -6266 |
| ELOVL6 | -6198 |
| NCOA6 | -6009 |
| PPARA | -5445 |
| MVD | -4365 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| HMGCR | -10938 |
| SCD | -9415 |
| HMGCS1 | -9158 |
| NCOA2 | -8959 |
| SQLE | -8695 |
| CARM1 | -8567 |
| CHD9 | -8549 |
| MTF1 | -8255 |
| PMVK | -8094 |
| SP1 | -7936 |
| TM7SF2 | -7337 |
| SREBF2 | -6976 |
| ACACA | -6898 |
| SMARCD3 | -6859 |
| FDPS | -6447 |
| RXRA | -6266 |
| ELOVL6 | -6198 |
| NCOA6 | -6009 |
| PPARA | -5445 |
| MVD | -4365 |
| MVK | -4328 |
| FASN | -3711 |
| TGS1 | -3648 |
| NFYA | -3313 |
| ACACB | -3115 |
| IDI1 | -2486 |
| SC5D | -2232 |
| GPAM | -1711 |
| CYP51A1 | -1296 |
| MED1 | -750 |
| GGPS1 | -429 |
| LSS | -256 |
| CREBBP | 66 |
| NCOA1 | 220 |
| SREBF1 | 550 |
| FDFT1 | 910 |
| TBL1XR1 | 1614 |
| NFYC | 2000 |
| DHCR7 | 2277 |
| HELZ2 | 3253 |
| NFYB | 5323 |
REACTOME_AMINE_LIGAND_BINDING_RECEPTORS
| 602 | |
|---|---|
| set | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS |
| setSize | 40 |
| pANOVA | 0.00208 |
| s.dist | 0.281 |
| p.adjustANOVA | 0.227 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| DRD5 | 10061 |
| TAAR8 | 9991 |
| TAAR1 | 9837 |
| HRH3 | 9245 |
| ADRA2C | 9020 |
| ADRA1B | 9009 |
| CHRM4 | 8860 |
| ADRA1A | 8688 |
| HTR1B | 8578 |
| DRD2 | 8046 |
| HTR1E | 7901 |
| ADRA2A | 7409 |
| HRH2 | 7342 |
| TAAR2 | 6657 |
| TAAR5 | 6017 |
| DRD3 | 5795 |
| HRH1 | 4811 |
| HTR6 | 4765 |
| ADRA2B | 4418 |
| DRD1 | 3735 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| DRD5 | 10061 |
| TAAR8 | 9991 |
| TAAR1 | 9837 |
| HRH3 | 9245 |
| ADRA2C | 9020 |
| ADRA1B | 9009 |
| CHRM4 | 8860 |
| ADRA1A | 8688 |
| HTR1B | 8578 |
| DRD2 | 8046 |
| HTR1E | 7901 |
| ADRA2A | 7409 |
| HRH2 | 7342 |
| TAAR2 | 6657 |
| TAAR5 | 6017 |
| DRD3 | 5795 |
| HRH1 | 4811 |
| HTR6 | 4765 |
| ADRA2B | 4418 |
| DRD1 | 3735 |
| ADRB3 | 2878 |
| HTR4 | 2759 |
| HTR5A | 2702 |
| HTR1D | 1919 |
| HTR1F | 1259 |
| ADRB2 | 768 |
| ADRA1D | 722 |
| HTR1A | -89 |
| CHRM3 | -713 |
| HTR7 | -726 |
| TAAR6 | -1932 |
| DRD4 | -4824 |
| CHRM1 | -4837 |
| HTR2B | -4867 |
| ADRB1 | -6400 |
| CHRM2 | -7066 |
| CHRM5 | -7863 |
| HTR2A | -10995 |
| TAAR9 | -11277 |
| HRH4 | -11329 |
REACTOME_INNATE_IMMUNE_SYSTEM
| 227 | |
|---|---|
| set | REACTOME_INNATE_IMMUNE_SYSTEM |
| setSize | 1002 |
| pANOVA | 0.00223 |
| s.dist | -0.0571 |
| p.adjustANOVA | 0.228 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| AZU1 | -11805 |
| FOLR3 | -11766 |
| IFNA7 | -11672 |
| BPIFB2 | -11660 |
| PLA2G2A | -11635 |
| SIGLEC5 | -11615 |
| FCGR3B | -11603 |
| CFHR5 | -11593 |
| STING1 | -11581 |
| MUC3A | -11573 |
| MPO | -11563 |
| REG3G | -11556 |
| S100A8 | -11505 |
| RNASE7 | -11493 |
| RNASE3 | -11488 |
| TARM1 | -11477 |
| CEACAM1 | -11458 |
| CEACAM3 | -11421 |
| DEFB124 | -11420 |
| CD300A | -11418 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| AZU1 | -11805.0 |
| FOLR3 | -11766.0 |
| IFNA7 | -11672.0 |
| BPIFB2 | -11660.0 |
| PLA2G2A | -11635.0 |
| SIGLEC5 | -11615.0 |
| FCGR3B | -11603.0 |
| CFHR5 | -11593.0 |
| STING1 | -11581.0 |
| MUC3A | -11573.0 |
| MPO | -11563.0 |
| REG3G | -11556.0 |
| S100A8 | -11505.0 |
| RNASE7 | -11493.0 |
| RNASE3 | -11488.0 |
| TARM1 | -11477.0 |
| CEACAM1 | -11458.0 |
| CEACAM3 | -11421.0 |
| DEFB124 | -11420.0 |
| CD300A | -11418.0 |
| TRIM4 | -11376.0 |
| PSMB11 | -11321.0 |
| HP | -11299.0 |
| ISG15 | -11272.0 |
| LRG1 | -11267.0 |
| NME2 | -11252.0 |
| DOK3 | -11187.0 |
| ELANE | -11131.0 |
| CTSG | -11118.0 |
| CFI | -11111.0 |
| TYROBP | -11079.0 |
| NLRC4 | -11069.0 |
| ADA2 | -11052.0 |
| TNFAIP6 | -11016.0 |
| FCN2 | -10996.0 |
| BRI3 | -10960.0 |
| GLIPR1 | -10945.0 |
| EPX | -10937.0 |
| MUC17 | -10933.0 |
| GHDC | -10913.0 |
| MAPK13 | -10900.0 |
| C5AR2 | -10895.0 |
| S100A9 | -10869.0 |
| DSG1 | -10854.0 |
| S100A7 | -10851.0 |
| SFTPD | -10798.0 |
| CAPZA2 | -10797.0 |
| C8B | -10740.0 |
| TREX1 | -10729.0 |
| HMOX1 | -10727.0 |
| PGLYRP2 | -10719.0 |
| MNDA | -10700.0 |
| RNASE6 | -10671.0 |
| LYZ | -10667.0 |
| AGPAT2 | -10653.0 |
| ARPC1A | -10590.0 |
| TRIM21 | -10586.0 |
| PLAU | -10533.0 |
| FGR | -10528.0 |
| BCL2L1 | -10519.0 |
| ATP6V0A4 | -10444.0 |
| MLEC | -10442.0 |
| TREM2 | -10396.0 |
| MS4A3 | -10389.0 |
| P2RX1 | -10381.0 |
| VAT1 | -10378.0 |
| COMMD3 | -10370.0 |
| ORMDL3 | -10326.0 |
| PELI2 | -10316.0 |
| CASP1 | -10218.0 |
| CLEC4A | -10217.0 |
| PSMB9 | -10214.0 |
| ALDH3B1 | -10213.0 |
| POLR3H | -10198.0 |
| PSMA5 | -10194.0 |
| SIRPB1 | -10186.0 |
| IL1B | -10174.0 |
| SELL | -10157.0 |
| GSTP1 | -10150.0 |
| BPIFA1 | -10142.0 |
| DYNLL1 | -10134.0 |
| LCP2 | -10127.0 |
| KRAS | -10121.0 |
| LAMTOR3 | -10113.0 |
| CYB5R3 | -10081.0 |
| TSPAN14 | -10027.0 |
| LAMTOR2 | -10010.0 |
| TLR1 | -10000.0 |
| DCD | -9957.0 |
| TUBB | -9940.0 |
| GGH | -9921.0 |
| TNIP2 | -9889.0 |
| MAP2K6 | -9860.0 |
| NOD1 | -9854.0 |
| ALAD | -9849.0 |
| PSMB8 | -9839.0 |
| VCL | -9835.0 |
| BIN2 | -9807.0 |
| WASF3 | -9654.0 |
| DEFB119 | -9652.0 |
| RAP1B | -9640.0 |
| MAPKAPK3 | -9638.0 |
| MUC15 | -9635.0 |
| S100B | -9624.0 |
| CTSD | -9587.0 |
| PPP2R5D | -9565.0 |
| CHRNB4 | -9556.0 |
| IFI16 | -9539.0 |
| CTSB | -9530.0 |
| SLC2A3 | -9521.0 |
| SIGLEC9 | -9512.0 |
| C9 | -9505.0 |
| CYLD | -9497.0 |
| PROS1 | -9491.0 |
| NFAM1 | -9480.0 |
| CD300LB | -9471.0 |
| B4GALT1 | -9470.0 |
| ENPP4 | -9450.0 |
| PIK3R2 | -9400.0 |
| PRSS3 | -9386.0 |
| TOMM70 | -9366.0 |
| VAPA | -9336.0 |
| CEACAM6 | -9322.0 |
| TMEM30A | -9317.0 |
| PPP2CA | -9312.0 |
| CTSK | -9296.0 |
| HLA-A | -9216.0 |
| IRAK3 | -9197.0 |
| NRAS | -9056.0 |
| GUSB | -9054.0 |
| CANT1 | -9052.0 |
| HLA-E | -9018.0 |
| PELI3 | -9012.0 |
| SERPINB6 | -9007.0 |
| MUCL1 | -8963.0 |
| TICAM1 | -8961.0 |
| POLR3GL | -8960.0 |
| FTH1 | -8939.0 |
| COLEC11 | -8936.0 |
| RAB3D | -8919.0 |
| SVIP | -8918.0 |
| NLRP1 | -8896.0 |
| EPPIN | -8872.0 |
| OSCAR | -8819.0 |
| MVP | -8815.0 |
| ATP6V0A1 | -8805.0 |
| TOM1 | -8801.0 |
| UBB | -8790.0 |
| RAB7A | -8782.0 |
| NCKAP1L | -8756.0 |
| MIF | -8741.0 |
| DEFB129 | -8730.0 |
| DEFB133 | -8700.0 |
| GPI | -8663.0 |
| REG3A | -8650.0 |
| RAB3A | -8649.0 |
| BST1 | -8638.0 |
| CD33 | -8566.0 |
| POLR2H | -8504.0 |
| RAC1 | -8501.0 |
| GPR84 | -8494.0 |
| ATP6V0D2 | -8443.0 |
| GNLY | -8436.0 |
| GYG1 | -8407.0 |
| POLR3B | -8382.0 |
| AHSG | -8346.0 |
| STBD1 | -8329.0 |
| CASP10 | -8326.0 |
| PSMB7 | -8319.0 |
| CEACAM8 | -8306.0 |
| CFH | -8267.0 |
| RPS6KA1 | -8254.0 |
| C4BPA | -8247.0 |
| CLEC4C | -8243.0 |
| MAPK14 | -8203.0 |
| NCF2 | -8194.0 |
| C8A | -8189.0 |
| ADAM8 | -8173.0 |
| PSME1 | -8170.0 |
| TANK | -8110.0 |
| PGLYRP4 | -8101.0 |
| SLPI | -8072.0 |
| ICAM3 | -8067.0 |
| LPO | -8060.0 |
| UBE2N | -8046.0 |
| PPIA | -8002.0 |
| C1R | -7999.0 |
| RHOA | -7993.0 |
| PSMB6 | -7992.0 |
| PECAM1 | -7988.0 |
| PTAFR | -7971.0 |
| ABI2 | -7937.0 |
| MAP3K7 | -7914.0 |
| PGLYRP3 | -7884.0 |
| NPC2 | -7879.0 |
| CYFIP1 | -7795.0 |
| NFKB1 | -7717.0 |
| AHCYL1 | -7708.0 |
| GMFG | -7690.0 |
| TRIM25 | -7651.0 |
| DEFB115 | -7631.0 |
| CRP | -7606.0 |
| OLR1 | -7605.0 |
| TXN | -7590.0 |
| SIGLEC14 | -7584.0 |
| PGAM1 | -7574.0 |
| TRAF2 | -7547.0 |
| S100A1 | -7543.0 |
| SERPINB1 | -7540.0 |
| SCAMP1 | -7530.0 |
| LIMK1 | -7521.0 |
| TLR3 | -7418.0 |
| ATP6V1G3 | -7405.0 |
| BST2 | -7399.0 |
| IFNB1 | -7347.0 |
| CD300E | -7296.0 |
| DNM3 | -7245.0 |
| MGST1 | -7244.0 |
| NCSTN | -7234.0 |
| ATP6V0D1 | -7183.0 |
| PSMC4 | -7169.0 |
| MAP3K8 | -7131.0 |
| WASL | -7100.0 |
| DEFB136 | -7095.0 |
| SLC2A5 | -7085.0 |
| ARPC4 | -7049.0 |
| POLR1D | -7042.0 |
| CD177 | -7035.0 |
| TXNIP | -7024.0 |
| ATP6V1B2 | -6988.0 |
| GAA | -6922.0 |
| SEMG1 | -6887.0 |
| JUN | -6880.0 |
| CASP9 | -6869.0 |
| ICAM2 | -6863.0 |
| WIPF3 | -6788.0 |
| HPSE | -6776.0 |
| CDA | -6771.0 |
| PTPRJ | -6741.0 |
| RAB4B | -6656.0 |
| CFHR4 | -6645.0 |
| DERA | -6640.0 |
| CLEC7A | -6623.0 |
| CLEC12A | -6595.0 |
| DNAJC3 | -6592.0 |
| HSPA1A | -6581.0 |
| PSME3 | -6558.0 |
| P2RX7 | -6546.0 |
| CTSZ | -6514.0 |
| ANXA2 | -6503.0 |
| HRNR | -6473.0 |
| FUCA1 | -6418.0 |
| EEA1 | -6416.0 |
| FTL | -6388.0 |
| CD47 | -6354.0 |
| PRCP | -6327.0 |
| SERPINA3 | -6321.0 |
| SNAP25 | -6279.0 |
| IDH1 | -6272.0 |
| ATP6V1E1 | -6244.0 |
| TICAM2 | -6240.0 |
| MUC20 | -6215.0 |
| LY96 | -6193.0 |
| NCKAP1 | -6168.0 |
| TBK1 | -6160.0 |
| CD58 | -6149.0 |
| STOM | -6138.0 |
| STAT6 | -6116.0 |
| PSMD14 | -6115.0 |
| MUC12 | -6112.0 |
| UNC13D | -6108.0 |
| B2M | -6084.0 |
| MAPK1 | -6079.0 |
| RIPK2 | -6072.0 |
| APAF1 | -6062.0 |
| TLR6 | -6002.0 |
| POLR3C | -5971.0 |
| PLD2 | -5960.0 |
| CCT2 | -5934.0 |
| TRPM2 | -5932.0 |
| RPS6KA5 | -5928.0 |
| C4BPB | -5918.0 |
| ITGAM | -5917.0 |
| CPNE1 | -5885.0 |
| PSMA7 | -5868.0 |
| IQGAP1 | -5864.0 |
| JUP | -5858.0 |
| PDAP1 | -5800.0 |
| FGG | -5755.0 |
| HMGB1 | -5752.0 |
| ITCH | -5751.0 |
| PRKACB | -5745.0 |
| TAB1 | -5712.0 |
| APP | -5711.0 |
| ERP44 | -5696.0 |
| HGSNAT | -5672.0 |
| NOS3 | -5661.0 |
| HMOX2 | -5659.0 |
| ART1 | -5593.0 |
| TMBIM1 | -5570.0 |
| IFNA16 | -5530.0 |
| RAB24 | -5500.0 |
| PAK1 | -5494.0 |
| PRKACA | -5493.0 |
| CPPED1 | -5468.0 |
| CD4 | -5453.0 |
| PTK2 | -5442.0 |
| SLC44A2 | -5361.0 |
| FCER1G | -5297.0 |
| HEBP2 | -5296.0 |
| IKBIP | -5274.0 |
| S100A11 | -5262.0 |
| AIM2 | -5239.0 |
| ATP6V1C1 | -5204.0 |
| SPTAN1 | -5203.0 |
| VAV1 | -5192.0 |
| SNAP29 | -5190.0 |
| PSMD7 | -5158.0 |
| FPR1 | -5112.0 |
| STK11IP | -5106.0 |
| DDX41 | -5091.0 |
| ACLY | -5064.0 |
| RAB6A | -5055.0 |
| RNASE2 | -5014.0 |
| ATG12 | -4993.0 |
| NLRC3 | -4981.0 |
| MAPK11 | -4950.0 |
| YPEL5 | -4855.0 |
| CFL1 | -4804.0 |
| ATP6V1G2 | -4799.0 |
| RASGRP2 | -4794.0 |
| ITGAV | -4786.0 |
| PSMD8 | -4743.0 |
| PIN1 | -4718.0 |
| CD63 | -4710.0 |
| LAMTOR1 | -4695.0 |
| COPB1 | -4689.0 |
| FPR2 | -4671.0 |
| NFATC3 | -4660.0 |
| CPNE3 | -4657.0 |
| DHX58 | -4639.0 |
| CLU | -4636.0 |
| BPIFB1 | -4627.0 |
| LILRB3 | -4575.0 |
| C1S | -4570.0 |
| IQGAP2 | -4528.0 |
| HSPA1B | -4491.0 |
| SERPINB10 | -4476.0 |
| DEFB121 | -4461.0 |
| ARSB | -4422.0 |
| CRK | -4418.0 |
| TNFAIP3 | -4408.0 |
| ATP6V1A | -4373.0 |
| GSDME | -4369.0 |
| SLCO4C1 | -4348.0 |
| PRKCD | -4339.0 |
| ARMC8 | -4315.0 |
| MRE11 | -4288.0 |
| CHUK | -4283.0 |
| C6orf120 | -4277.0 |
| MALT1 | -4257.0 |
| TIMP2 | -4253.0 |
| VCP | -4221.0 |
| ATG5 | -4219.0 |
| WIPF1 | -4212.0 |
| PSMD5 | -4189.0 |
| FCGR2A | -4179.0 |
| AP1M1 | -4178.0 |
| RAP2B | -4176.0 |
| CRISPLD2 | -4145.0 |
| CPB2 | -4139.0 |
| C2 | -4136.0 |
| RAB37 | -4129.0 |
| RIPK1 | -4127.0 |
| FOS | -4091.0 |
| BPIFA2 | -4069.0 |
| PRKACG | -4062.0 |
| SRC | -4047.0 |
| MAVS | -4030.0 |
| RNASE8 | -4019.0 |
| STK10 | -4011.0 |
| RAB18 | -3976.0 |
| IMPDH1 | -3971.0 |
| UBC | -3960.0 |
| SOCS1 | -3954.0 |
| NHLRC3 | -3939.0 |
| PSMD11 | -3936.0 |
| RAB31 | -3923.0 |
| PSMB2 | -3889.0 |
| CHGA | -3830.0 |
| KRT1 | -3821.0 |
| HCK | -3809.0 |
| ATG7 | -3780.0 |
| TMEM179B | -3778.0 |
| DDOST | -3727.0 |
| DHX36 | -3700.0 |
| DOCK2 | -3690.0 |
| WASF2 | -3679.0 |
| BPI | -3663.0 |
| ANO6 | -3646.0 |
| DEFB116 | -3640.0 |
| PIK3R1 | -3634.0 |
| IFNA13 | -3617.0 |
| PPP3CB | -3495.0 |
| CFB | -3488.0 |
| LRRFIP1 | -3485.0 |
| NEU1 | -3479.0 |
| PSMA6 | -3468.0 |
| UBE2K | -3457.0 |
| CFD | -3456.0 |
| ATP6V1C2 | -3444.0 |
| ARG1 | -3412.0 |
| PSMD9 | -3390.0 |
| CASP2 | -3387.0 |
| RPS27A | -3374.0 |
| ALDOA | -3343.0 |
| LTF | -3342.0 |
| GRN | -3338.0 |
| TEC | -3317.0 |
| SDCBP | -3305.0 |
| CKAP4 | -3302.0 |
| ROCK1 | -3299.0 |
| ABI1 | -3295.0 |
| SNAP23 | -3277.0 |
| MEFV | -3243.0 |
| MYH2 | -3218.0 |
| PLAC8 | -3202.0 |
| FGL2 | -3167.0 |
| SUGT1 | -3153.0 |
| RELB | -3151.0 |
| KPNB1 | -3143.0 |
| RELA | -3097.0 |
| PSME4 | -3068.0 |
| HSP90B1 | -3056.0 |
| PPP2R1A | -2973.0 |
| COMMD9 | -2948.0 |
| PAK2 | -2914.0 |
| IRAG2 | -2895.0 |
| DIAPH1 | -2889.0 |
| GCA | -2880.0 |
| DEGS1 | -2851.0 |
| MAP3K14 | -2839.0 |
| PIK3CB | -2806.0 |
| C5AR1 | -2800.0 |
| VAV3 | -2783.0 |
| PYCARD | -2753.0 |
| CAPN1 | -2688.0 |
| GOLGA7 | -2677.0 |
| POLR2L | -2674.0 |
| RBSN | -2633.0 |
| NCKIPSD | -2610.0 |
| ABCA13 | -2595.0 |
| CAPZA1 | -2585.0 |
| C7 | -2583.0 |
| UBE2M | -2548.0 |
| CD68 | -2546.0 |
| MAPKAPK2 | -2537.0 |
| MAN2B1 | -2531.0 |
| PPP2CB | -2525.0 |
| MAPK8 | -2519.0 |
| CPN2 | -2493.0 |
| CTSS | -2467.0 |
| GAB2 | -2455.0 |
| GALNS | -2454.0 |
| PSMC5 | -2407.0 |
| ATOX1 | -2384.0 |
| USP14 | -2360.0 |
| ACTG1 | -2359.0 |
| MUC7 | -2354.0 |
| SIRPA | -2352.0 |
| MAPK9 | -2338.0 |
| NFKBIA | -2311.0 |
| C1orf35 | -2310.0 |
| MUC13 | -2295.0 |
| DHX9 | -2290.0 |
| IRAK2 | -2284.0 |
| HLA-B | -2277.0 |
| LILRB2 | -2262.0 |
| CASP8 | -2260.0 |
| NF2 | -2256.0 |
| APRT | -2222.0 |
| ATF1 | -2197.0 |
| PRDX6 | -2193.0 |
| IRF3 | -2182.0 |
| SARM1 | -2175.0 |
| UBE2L6 | -2155.0 |
| ATP6V1G1 | -2067.0 |
| ADGRG3 | -2056.0 |
| C4A | -2042.5 |
| C4B | -2042.5 |
| PRTN3 | -2041.0 |
| ITGAL | -2024.0 |
| PLAUR | -2012.0 |
| PLA2G6 | -2009.0 |
| ITPR2 | -1996.0 |
| PSMA2 | -1982.0 |
| BTRC | -1967.0 |
| DEFB110 | -1935.0 |
| GM2A | -1908.0 |
| CYSTM1 | -1894.0 |
| PGLYRP1 | -1886.0 |
| PELI1 | -1841.0 |
| CARD11 | -1810.0 |
| SERPINA1 | -1802.0 |
| AP2A2 | -1773.0 |
| BIRC2 | -1766.0 |
| CUL1 | -1737.0 |
| ALPK1 | -1698.0 |
| MAP2K7 | -1672.0 |
| NOD2 | -1669.0 |
| CD59 | -1661.0 |
| ATP6V1B1 | -1653.0 |
| MGAM | -1648.0 |
| ARPC3 | -1613.0 |
| PIK3C3 | -1508.0 |
| IMPDH2 | -1455.0 |
| MASP1 | -1407.0 |
| SURF4 | -1326.0 |
| IGF2R | -1310.0 |
| CASP4 | -1302.0 |
| CAND1 | -1292.0 |
| BPIFB4 | -1254.0 |
| CNPY3 | -1246.0 |
| PRKCSH | -1237.0 |
| MEF2C | -1196.0 |
| S100A7A | -1185.0 |
| DYNC1H1 | -1161.0 |
| PTPN11 | -1156.0 |
| LAIR1 | -1133.0 |
| DUSP4 | -1110.0 |
| VAV2 | -1107.0 |
| PLD3 | -1066.0 |
| CTNNB1 | -1056.0 |
| SOS1 | -1037.0 |
| CCT8 | -994.0 |
| RNASET2 | -993.0 |
| RNF216 | -974.0 |
| UBE2D3 | -967.0 |
| FCGR3A | -965.0 |
| DNM1 | -940.0 |
| ITPR1 | -933.0 |
| PYGB | -911.0 |
| HBB | -860.0 |
| USP18 | -834.0 |
| ELMO1 | -796.0 |
| RAP1A | -776.0 |
| LGALS3 | -717.0 |
| TREM1 | -678.0 |
| FBXW11 | -659.0 |
| PSMB1 | -649.0 |
| TUBB4B | -641.0 |
| ARPC2 | -618.0 |
| FLG2 | -605.0 |
| NFKB2 | -568.0 |
| DEFB134 | -507.0 |
| MUC4 | -482.0 |
| OSTF1 | -472.0 |
| SLC15A4 | -417.0 |
| CD44 | -393.0 |
| NFATC2 | -352.0 |
| ALOX5 | -349.0 |
| DEFB125 | -342.0 |
| PSMC1 | -332.0 |
| AGA | -324.0 |
| ADAM10 | -322.0 |
| HK3 | -306.0 |
| DYNC1LI1 | -283.0 |
| MYO10 | -269.0 |
| SIGLEC15 | -237.0 |
| PSMD13 | -227.0 |
| MAP2K4 | -208.0 |
| VPS35L | -200.0 |
| PGM2 | -188.0 |
| EEF1A1 | -169.0 |
| RAC2 | -144.0 |
| ATP6V1H | -57.0 |
| XRCC6 | -18.0 |
| PSMC6 | 25.0 |
| PRKCQ | 41.0 |
| CREBBP | 66.0 |
| CYFIP2 | 102.0 |
| PSAP | 108.0 |
| PGM1 | 109.0 |
| NKIRAS2 | 116.0 |
| PIK3R4 | 133.0 |
| PSMD6 | 166.0 |
| TAB2 | 181.0 |
| CREG1 | 208.0 |
| CD53 | 210.0 |
| MUC5AC | 225.0 |
| ELMO2 | 249.0 |
| PSMF1 | 351.0 |
| SHC1 | 356.0 |
| POLR1C | 402.0 |
| ATP6V0A2 | 406.0 |
| PPIE | 429.0 |
| CSNK2B | 434.0 |
| BIRC3 | 435.0 |
| PSMD2 | 438.0 |
| UBE2D1 | 455.0 |
| POLR3K | 478.0 |
| TRIM32 | 479.0 |
| CRACR2A | 495.0 |
| HSP90AA1 | 498.0 |
| PDXK | 560.0 |
| CR1 | 588.0 |
| IFIH1 | 615.0 |
| MMP9 | 632.0 |
| CTSA | 663.0 |
| QSOX1 | 666.0 |
| PKM | 696.0 |
| DSP | 720.0 |
| YES1 | 759.0 |
| ANPEP | 783.0 |
| ATP8A1 | 794.0 |
| C1QA | 803.0 |
| PSMB10 | 869.0 |
| RNF125 | 881.0 |
| NCR2 | 887.0 |
| GNS | 893.0 |
| AGL | 905.0 |
| RASGRP4 | 911.0 |
| FUCA2 | 967.0 |
| ACTR10 | 974.0 |
| ITK | 1071.0 |
| PSMC2 | 1115.0 |
| PSMD1 | 1119.0 |
| PLEKHO2 | 1148.0 |
| PTPRC | 1183.0 |
| QPCT | 1209.0 |
| CD19 | 1214.0 |
| PTPRN2 | 1227.0 |
| HSPA6 | 1232.0 |
| RAF1 | 1284.0 |
| CTSL | 1302.0 |
| FYN | 1339.0 |
| SIKE1 | 1376.0 |
| CAB39 | 1473.0 |
| NCK1 | 1474.0 |
| CXCR2 | 1512.0 |
| RNF135 | 1519.0 |
| TKFC | 1564.0 |
| GSN | 1576.0 |
| DGAT1 | 1578.0 |
| NDUFC2 | 1597.0 |
| CD180 | 1607.0 |
| DOCK1 | 1613.0 |
| NLRP3 | 1626.0 |
| SFTPA2 | 1636.0 |
| PFKL | 1650.0 |
| MUC16 | 1657.0 |
| C1QB | 1677.0 |
| HTN3 | 1683.0 |
| ITGB2 | 1695.0 |
| PLD4 | 1715.0 |
| KLRK1 | 1719.0 |
| UBA7 | 1721.0 |
| PIGR | 1733.0 |
| NIT2 | 1755.0 |
| CDK13 | 1757.0 |
| RAB44 | 1783.0 |
| PTPN4 | 1788.0 |
| ITPR3 | 1792.0 |
| PLPP5 | 1794.0 |
| DTX4 | 1828.0 |
| PSTPIP1 | 1841.0 |
| PIK3CA | 1864.0 |
| TXNDC5 | 1866.0 |
| DEFA4 | 1922.0 |
| MYO1C | 1935.0 |
| KCMF1 | 1940.0 |
| PSME2 | 1954.0 |
| RASGRP1 | 1955.0 |
| AGER | 1979.0 |
| AMPD3 | 1991.0 |
| GDI2 | 2006.0 |
| CSTB | 2024.0 |
| IKBKB | 2113.0 |
| RIPK3 | 2140.0 |
| CTSH | 2150.0 |
| EEF2 | 2157.0 |
| MMP25 | 2195.0 |
| DUSP7 | 2218.0 |
| COLEC10 | 2241.0 |
| S100P | 2282.0 |
| PDPK1 | 2289.0 |
| NFASC | 2347.0 |
| MAP2K1 | 2383.0 |
| LRRC7 | 2386.0 |
| RHOF | 2412.0 |
| DPP7 | 2430.0 |
| IRAK4 | 2469.0 |
| ARL8A | 2478.0 |
| PSMD12 | 2494.0 |
| TIFA | 2526.0 |
| WIPF2 | 2527.0 |
| DEFB118 | 2556.0 |
| GRAP2 | 2559.0 |
| ACTR2 | 2584.0 |
| SIGIRR | 2587.0 |
| FCN3 | 2588.0 |
| PPP3CA | 2590.0 |
| TLR10 | 2617.0 |
| TRAPPC1 | 2657.0 |
| VAMP8 | 2687.0 |
| SYNGR1 | 2694.0 |
| ATP6V0E1 | 2704.0 |
| PLCG1 | 2718.0 |
| F2 | 2752.0 |
| ORM2 | 2766.0 |
| RAB5C | 2816.0 |
| SLC11A1 | 2875.0 |
| CAMP | 2901.0 |
| BAIAP2 | 2933.0 |
| IFNA14 | 2949.0 |
| NBEAL2 | 2958.0 |
| LEAP2 | 2979.0 |
| LPCAT1 | 2980.0 |
| NLRC5 | 2995.0 |
| RAB10 | 3030.0 |
| UNC93B1 | 3036.0 |
| PNP | 3069.0 |
| MANBA | 3097.0 |
| GSDMD | 3114.0 |
| MUC5B | 3137.0 |
| LBP | 3156.0 |
| PCBP2 | 3159.0 |
| ARPC1B | 3164.0 |
| PANX1 | 3226.0 |
| ATP11B | 3236.0 |
| FCN1 | 3271.0 |
| PLCG2 | 3274.0 |
| FABP5 | 3303.0 |
| IRF7 | 3309.0 |
| RHOG | 3326.0 |
| DEFB127 | 3328.0 |
| ITGAX | 3356.0 |
| BCL2 | 3392.0 |
| DYNLT1 | 3429.0 |
| DEFB113 | 3451.0 |
| ATP11A | 3463.0 |
| OLFM4 | 3525.0 |
| HTN1 | 3531.0 |
| TOLLIP | 3534.0 |
| WASF1 | 3538.0 |
| BPIFB6 | 3550.0 |
| GLB1 | 3562.0 |
| ARPC5 | 3563.0 |
| PRKCE | 3573.0 |
| PSMA8 | 3597.0 |
| XRCC5 | 3659.0 |
| ABL1 | 3669.0 |
| MME | 3675.0 |
| NOS1 | 3680.0 |
| DNAJC5 | 3699.0 |
| ATF2 | 3723.0 |
| CD209 | 3731.0 |
| POLR2E | 3770.0 |
| POLR3E | 3783.0 |
| ATP6V0C | 3790.0 |
| N4BP1 | 3796.0 |
| SEM1 | 3801.0 |
| RPS6KA2 | 3816.0 |
| PRG2 | 3894.0 |
| DBNL | 3923.0 |
| KCNAB2 | 3924.0 |
| C5 | 3928.0 |
| TAX1BP1 | 3958.0 |
| CLEC10A | 3963.0 |
| DUSP3 | 3987.0 |
| RAB14 | 4054.0 |
| HEXB | 4073.0 |
| CHI3L1 | 4080.0 |
| BCL10 | 4105.0 |
| RAB5B | 4118.0 |
| LY86 | 4159.0 |
| MAP2K3 | 4168.0 |
| TMEM63A | 4182.0 |
| PSMB4 | 4183.0 |
| VTN | 4192.0 |
| CYBA | 4195.0 |
| HSPA8 | 4201.0 |
| CCL17 | 4204.0 |
| A1BG | 4242.0 |
| PKP1 | 4262.0 |
| MEF2A | 4284.0 |
| RIGI | 4352.0 |
| PSMD4 | 4365.0 |
| S100A12 | 4390.0 |
| PPP3R1 | 4405.0 |
| CALM1 | 4408.0 |
| FAF2 | 4459.0 |
| TRAF6 | 4480.0 |
| LCK | 4485.0 |
| CALML5 | 4510.0 |
| CREB1 | 4535.0 |
| MUC1 | 4559.0 |
| CD46 | 4594.0 |
| MAPK7 | 4610.0 |
| ACTR3 | 4677.0 |
| DUSP6 | 4681.0 |
| NAPRT | 4709.0 |
| EP300 | 4777.0 |
| UBE2D2 | 4781.0 |
| IST1 | 4793.0 |
| SKP1 | 4805.0 |
| MS4A2 | 4843.0 |
| CPN1 | 4854.0 |
| LAT2 | 4859.0 |
| DEFB126 | 4876.0 |
| HLA-C | 4893.0 |
| C8G | 4897.0 |
| CGAS | 4934.0 |
| ORM1 | 4997.0 |
| PTPN6 | 5005.0 |
| LAMP1 | 5015.0 |
| NCF4 | 5085.0 |
| MAPK12 | 5108.0 |
| TLR4 | 5129.0 |
| TMC6 | 5132.0 |
| NLRX1 | 5151.0 |
| DEFA5 | 5153.0 |
| CLEC4D | 5154.0 |
| FCER1A | 5156.0 |
| CD36 | 5163.0 |
| ARSA | 5204.0 |
| PRKDC | 5209.0 |
| CMTM6 | 5223.0 |
| SFTPA1 | 5237.0 |
| DNM2 | 5273.0 |
| DEFB132 | 5282.0 |
| POLR3A | 5295.0 |
| SYK | 5298.0 |
| CAP1 | 5344.0 |
| LYN | 5354.0 |
| MAP3K1 | 5385.0 |
| POLR3F | 5424.0 |
| CARD9 | 5465.0 |
| DNAJC13 | 5472.0 |
| EPPIN-WFDC6 | 5503.0 |
| MCEMP1 | 5508.0 |
| ARHGAP45 | 5514.0 |
| LTA4H | 5548.0 |
| ATP6V0B | 5556.0 |
| ATP6V0E2 | 5580.0 |
| TLR2 | 5585.0 |
| PSMA4 | 5588.0 |
| LAT | 5591.0 |
| PSMB5 | 5606.0 |
| PSEN1 | 5639.0 |
| RAB27A | 5652.0 |
| PTPRB | 5734.0 |
| ALDOC | 5770.0 |
| AOC1 | 5771.0 |
| GRB2 | 5787.0 |
| MYH9 | 5790.0 |
| NFATC1 | 5820.0 |
| MUC21 | 5834.0 |
| IFNA5 | 5883.0 |
| MYO5A | 5901.0 |
| TRAF3 | 5929.0 |
| PADI2 | 5952.0 |
| ATP6V1E2 | 5954.0 |
| AAMP | 5956.0 |
| ECSIT | 5962.0 |
| ITLN1 | 5988.0 |
| ACTR1B | 5991.0 |
| ACTB | 6012.0 |
| UBA3 | 6013.0 |
| TIRAP | 6033.0 |
| HSP90AB1 | 6061.0 |
| PAFAH1B2 | 6094.0 |
| APEH | 6123.0 |
| MAPK10 | 6185.0 |
| DSN1 | 6194.0 |
| C6 | 6203.0 |
| ZBP1 | 6222.0 |
| ATP6V1D | 6253.0 |
| TP53 | 6303.0 |
| LILRA3 | 6345.0 |
| FRK | 6360.0 |
| UBR4 | 6390.0 |
| MYO9B | 6401.0 |
| UBE2V1 | 6498.0 |
| POLR2F | 6499.0 |
| IFNA6 | 6504.0 |
| POLR3G | 6505.0 |
| VRK3 | 6506.0 |
| PSMB3 | 6513.0 |
| PSMA1 | 6519.0 |
| HVCN1 | 6522.0 |
| CR2 | 6524.0 |
| POLR2K | 6527.0 |
| TNFRSF1B | 6580.0 |
| DEFB123 | 6590.0 |
| MAPK3 | 6757.0 |
| TLR5 | 6762.0 |
| PI3 | 6774.0 |
| IFNA2 | 6799.0 |
| CDC42 | 6814.0 |
| HERC5 | 6832.0 |
| PLPP4 | 6860.0 |
| POLR3D | 6879.0 |
| CLEC5A | 6883.0 |
| PSMD3 | 6889.0 |
| ACAA1 | 6926.0 |
| PPP2R1B | 6984.0 |
| SERPING1 | 7035.0 |
| DEFB104A | 7057.5 |
| DEFB104B | 7057.5 |
| CRCP | 7061.0 |
| CD55 | 7097.0 |
| DEFB135 | 7182.0 |
| TCIRG1 | 7186.0 |
| NLRP4 | 7203.0 |
| HRAS | 7211.0 |
| COTL1 | 7237.0 |
| PTX3 | 7277.0 |
| CTSC | 7289.0 |
| CEP290 | 7327.0 |
| TRIM56 | 7332.0 |
| MUC6 | 7384.0 |
| FCAR | 7473.0 |
| NOS2 | 7525.0 |
| ILF2 | 7531.0 |
| ASAH1 | 7557.0 |
| ATP8B4 | 7668.0 |
| ATAD3B | 7679.0 |
| CST3 | 7834.0 |
| PYGL | 7851.0 |
| NKIRAS1 | 7855.0 |
| CFHR2 | 7898.0 |
| UBA52 | 7910.0 |
| CRISP3 | 7919.0 |
| APOB | 7935.0 |
| NFKBIB | 7961.0 |
| CD81 | 7963.0 |
| CTSV | 7969.0 |
| CNN2 | 7973.0 |
| PSMA3 | 7987.0 |
| CDC34 | 7992.0 |
| MBL2 | 7999.0 |
| FADD | 8035.0 |
| PLD1 | 8058.0 |
| TCN1 | 8065.0 |
| DEFA6 | 8068.0 |
| PSMC3 | 8087.0 |
| PA2G4 | 8102.0 |
| MASP2 | 8168.0 |
| ARHGAP9 | 8328.0 |
| CD247 | 8350.0 |
| ADGRE5 | 8456.0 |
| CD14 | 8569.0 |
| TLR9 | 8643.0 |
| LRRC14 | 8663.0 |
| ACP3 | 8699.0 |
| C3 | 8800.0 |
| DEFB1 | 8808.0 |
| DEFB128 | 8809.0 |
| PTGES2 | 8823.0 |
| IKBKE | 8868.0 |
| BRK1 | 8876.0 |
| CXCR1 | 8889.0 |
| TXK | 8907.0 |
| TTR | 8913.0 |
| CHIT1 | 8919.0 |
| DSC1 | 8943.0 |
| TBC1D10C | 8945.0 |
| CAT | 9052.0 |
| C1QC | 9063.0 |
| SERPINB12 | 9075.0 |
| MYD88 | 9085.0 |
| CLEC4E | 9110.0 |
| CD93 | 9142.0 |
| MMP8 | 9198.0 |
| LGMN | 9338.0 |
| FGA | 9347.0 |
| ADGRE3 | 9363.0 |
| PPBP | 9375.0 |
| SLC27A2 | 9377.0 |
| IFNA1 | 9407.0 |
| VNN1 | 9418.0 |
| LCN2 | 9447.0 |
| C3AR1 | 9470.0 |
| SRP14 | 9527.0 |
| RETN | 9539.0 |
| CD3G | 9577.0 |
| FGB | 9603.0 |
| ATP6V1F | 9625.0 |
| CLEC6A | 9748.0 |
| KLRD1 | 9888.0 |
| CCR6 | 9905.0 |
| PRG3 | 9917.0 |
| CCR2 | 9938.0 |
| GZMM | 9969.0 |
| CXCL1 | 9982.0 |
| SAA1 | 10054.0 |
| CCL22 | 10065.0 |
| DEFB114 | 10076.0 |
| SERPINB3 | 10078.0 |
| IFNA8 | 10087.0 |
| IFNA21 | 10088.0 |
REACTOME_PD_1_SIGNALING
| 646 | |
|---|---|
| set | REACTOME_PD_1_SIGNALING |
| setSize | 21 |
| pANOVA | 0.00261 |
| s.dist | 0.379 |
| p.adjustANOVA | 0.252 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CD3D | 9965 |
| PDCD1 | 9937 |
| CD3E | 9583 |
| CD3G | 9577 |
| HLA-DRA | 9049 |
| HLA-DQB2 | 8376 |
| CD247 | 8350 |
| CSK | 7490 |
| PTPN6 | 5005 |
| LCK | 4485 |
| HLA-DPB1 | 2051 |
| PDCD1LG2 | 1575 |
| HLA-DPA1 | 995 |
| HLA-DQB1 | 884 |
| HLA-DRB5 | -543 |
| CD274 | -1153 |
| PTPN11 | -1156 |
| HLA-DQA1 | -1417 |
| HLA-DRB1 | -1914 |
| CD4 | -5453 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CD3D | 9965 |
| PDCD1 | 9937 |
| CD3E | 9583 |
| CD3G | 9577 |
| HLA-DRA | 9049 |
| HLA-DQB2 | 8376 |
| CD247 | 8350 |
| CSK | 7490 |
| PTPN6 | 5005 |
| LCK | 4485 |
| HLA-DPB1 | 2051 |
| PDCD1LG2 | 1575 |
| HLA-DPA1 | 995 |
| HLA-DQB1 | 884 |
| HLA-DRB5 | -543 |
| CD274 | -1153 |
| PTPN11 | -1156 |
| HLA-DQA1 | -1417 |
| HLA-DRB1 | -1914 |
| CD4 | -5453 |
| HLA-DQA2 | -5579 |
REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION
| 1635 | |
|---|---|
| set | REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION |
| setSize | 296 |
| pANOVA | 0.00302 |
| s.dist | -0.1 |
| p.adjustANOVA | 0.252 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TRIM4 | -11376 |
| FBXO40 | -11353 |
| PSMB11 | -11321 |
| SOCS3 | -11181 |
| KEAP1 | -11041 |
| FBXW4 | -10879 |
| UBE2E3 | -10821 |
| KBTBD7 | -10811 |
| UBE2E1 | -10694 |
| UBE3D | -10617 |
| TRIM21 | -10586 |
| ZNRF1 | -10498 |
| UBE2S | -10441 |
| NPEPPS | -10282 |
| HERC6 | -10276 |
| ASB8 | -10245 |
| PSMB9 | -10214 |
| PSMA5 | -10194 |
| KLHL42 | -10006 |
| PSMB8 | -9839 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TRIM4 | -11376 |
| FBXO40 | -11353 |
| PSMB11 | -11321 |
| SOCS3 | -11181 |
| KEAP1 | -11041 |
| FBXW4 | -10879 |
| UBE2E3 | -10821 |
| KBTBD7 | -10811 |
| UBE2E1 | -10694 |
| UBE3D | -10617 |
| TRIM21 | -10586 |
| ZNRF1 | -10498 |
| UBE2S | -10441 |
| NPEPPS | -10282 |
| HERC6 | -10276 |
| ASB8 | -10245 |
| PSMB9 | -10214 |
| PSMA5 | -10194 |
| KLHL42 | -10006 |
| PSMB8 | -9839 |
| FBXL18 | -9827 |
| UBE2J2 | -9795 |
| HACE1 | -9671 |
| FBXO9 | -9601 |
| MEX3C | -9537 |
| RNF34 | -9527 |
| UBE2G1 | -9475 |
| RBX1 | -9464 |
| UBE2D4 | -9310 |
| UBA6 | -9129 |
| ASB16 | -9015 |
| FBXO4 | -8966 |
| ASB1 | -8924 |
| UBB | -8790 |
| ANAPC13 | -8657 |
| TRIM39 | -8616 |
| ANAPC11 | -8493 |
| FBXO32 | -8422 |
| DTX3L | -8410 |
| HERC1 | -8328 |
| PSMB7 | -8319 |
| FBXO10 | -8279 |
| UBE2U | -8274 |
| UBE2H | -8268 |
| SIAH2 | -8177 |
| PSME1 | -8170 |
| LRRC41 | -8160 |
| RNF7 | -8107 |
| TPP2 | -8091 |
| KBTBD8 | -8064 |
| UBE2N | -8046 |
| VHL | -8019 |
| PSMB6 | -7992 |
| UBE2Q2 | -7895 |
| KLHL22 | -7774 |
| UBE2W | -7697 |
| BTBD6 | -7679 |
| CDC23 | -7642 |
| FBXO15 | -7637 |
| LRR1 | -7388 |
| ANAPC1 | -7349 |
| FBXW8 | -7200 |
| PSMC4 | -7169 |
| KLHL41 | -6993 |
| CUL3 | -6971 |
| HECTD2 | -6964 |
| LMO7 | -6825 |
| FBXL12 | -6609 |
| PSME3 | -6558 |
| ASB5 | -6553 |
| TRAF7 | -6509 |
| UBE2J1 | -6458 |
| KCTD6 | -6437 |
| RNF182 | -6389 |
| RNF138 | -6300 |
| PSMD14 | -6115 |
| LTN1 | -6065 |
| FBXO27 | -6039 |
| KLHL2 | -5902 |
| LRSAM1 | -5886 |
| PSMA7 | -5868 |
| CDC26 | -5830 |
| ITCH | -5751 |
| TRIM37 | -5717 |
| PRKN | -5662 |
| LNPEP | -5563 |
| FBXW7 | -5521 |
| HECTD1 | -5410 |
| ASB6 | -5351 |
| TRIM63 | -5341 |
| DZIP3 | -5336 |
| PSMD7 | -5158 |
| SKP2 | -5131 |
| FBXW9 | -5128 |
| UBE2B | -5041 |
| KLHL20 | -4769 |
| UBE2R2 | -4758 |
| FBXO2 | -4755 |
| PSMD8 | -4743 |
| UNKL | -4502 |
| FBXW12 | -4352 |
| ANAPC5 | -4281 |
| THOP1 | -4236 |
| PSMD5 | -4189 |
| RNF25 | -4183 |
| HERC2 | -4168 |
| TRIM41 | -4148 |
| TRAIP | -4121 |
| UBE3C | -4068 |
| UBC | -3960 |
| SOCS1 | -3954 |
| PSMD11 | -3936 |
| PSMB2 | -3889 |
| FBXO11 | -3872 |
| ASB10 | -3832 |
| FBXL19 | -3826 |
| ATG7 | -3780 |
| BTBD1 | -3699 |
| PSMA6 | -3468 |
| UBE2K | -3457 |
| PSMD9 | -3390 |
| RPS27A | -3374 |
| FBXO21 | -3221 |
| ANAPC7 | -3205 |
| UBE2F | -3128 |
| UBE2Z | -3125 |
| UBE2C | -3089 |
| KLHL5 | -3086 |
| PSME4 | -3068 |
| CUL7 | -3027 |
| RNF144B | -2944 |
| FBXW10 | -2915 |
| FBXL13 | -2884 |
| FBXL14 | -2881 |
| TRIP12 | -2792 |
| MYLIP | -2774 |
| FBXL5 | -2667 |
| UBE2O | -2625 |
| UBE2M | -2548 |
| SMURF2 | -2453 |
| SPSB2 | -2445 |
| NEDD4L | -2440 |
| PSMC5 | -2407 |
| ARIH2 | -2357 |
| CUL5 | -2334 |
| ASB3 | -2278 |
| MGRN1 | -2270 |
| UBE2L6 | -2155 |
| HECW2 | -2109 |
| PSMA2 | -1982 |
| BTRC | -1967 |
| SPSB4 | -1887 |
| RNF115 | -1801 |
| KLHL25 | -1795 |
| FBXL15 | -1767 |
| CUL1 | -1737 |
| FBXO22 | -1717 |
| KLHL11 | -1709 |
| KLHL3 | -1641 |
| CCNF | -1558 |
| HECTD3 | -1524 |
| FBXO31 | -1492 |
| UBAC1 | -1408 |
| UBR2 | -1351 |
| CBLB | -1241 |
| UBE2Q1 | -1193 |
| LONRF1 | -1149 |
| TRIM36 | -1145 |
| FBXL20 | -1069 |
| UBOX5 | -996 |
| NEDD4 | -968 |
| UBE2D3 | -967 |
| CUL2 | -848 |
| FBXO44 | -824 |
| UBR1 | -697 |
| FBXW11 | -659 |
| PSMB1 | -649 |
| HERC4 | -634 |
| UBE2G2 | -598 |
| UFL1 | -459 |
| PSMC1 | -332 |
| PSMD13 | -227 |
| AREL1 | -51 |
| PSMC6 | 25 |
| MKRN1 | 46 |
| RNF213 | 94 |
| PSMD6 | 166 |
| RNF126 | 179 |
| RNF114 | 243 |
| SMURF1 | 283 |
| PJA2 | 299 |
| RNF19A | 315 |
| PSMF1 | 351 |
| PSMD2 | 438 |
| UBE2D1 | 455 |
| TRIM32 | 479 |
| FBXO7 | 727 |
| RBBP6 | 732 |
| ASB17 | 822 |
| PSMB10 | 869 |
| FZR1 | 907 |
| FBXL7 | 1026 |
| UBE2V2 | 1082 |
| ASB15 | 1096 |
| RNF41 | 1099 |
| PSMC2 | 1115 |
| PSMD1 | 1119 |
| ASB13 | 1225 |
| UBE3B | 1410 |
| ZNRF2 | 1471 |
| SH3RF1 | 1515 |
| UBE3A | 1556 |
| ZBTB16 | 1557 |
| SIAH1 | 1646 |
| RBCK1 | 1694 |
| RNF19B | 1708 |
| UBA7 | 1721 |
| FBXO30 | 1837 |
| PSME2 | 1954 |
| WSB1 | 1990 |
| UBE2L3 | 2027 |
| ASB14 | 2057 |
| ASB2 | 2410 |
| WWP1 | 2440 |
| PSMD12 | 2494 |
| FBXL4 | 2504 |
| RCHY1 | 2542 |
| ANAPC10 | 2561 |
| BLMH | 2676 |
| ANAPC4 | 2773 |
| KLHL9 | 2843 |
| RNF123 | 2854 |
| CDC16 | 3095 |
| GAN | 3119 |
| DET1 | 3216 |
| KBTBD6 | 3229 |
| RNF220 | 3332 |
| CDC20 | 3349 |
| DCAF1 | 3391 |
| TRIM11 | 3594 |
| PSMA8 | 3597 |
| FBXW2 | 3630 |
| TRIM50 | 3774 |
| SEM1 | 3801 |
| GLMN | 3820 |
| UBA5 | 3893 |
| ANAPC2 | 4109 |
| PSMB4 | 4183 |
| FBXO41 | 4295 |
| CDC27 | 4326 |
| PSMD4 | 4365 |
| FBXW5 | 4411 |
| RNF6 | 4576 |
| RNF130 | 4582 |
| RNF14 | 4686 |
| UBE2D2 | 4781 |
| STUB1 | 4799 |
| SKP1 | 4805 |
| HERC3 | 4807 |
| ASB7 | 4873 |
| FBXL3 | 4875 |
| RNF111 | 5062 |
| PSMA4 | 5588 |
| PSMB5 | 5606 |
| UBE2E2 | 5610 |
| FBXO6 | 5996 |
| KLHL21 | 6006 |
| FBXL22 | 6010 |
| UBA3 | 6013 |
| ELOC | 6137 |
| MIB2 | 6161 |
| SPSB1 | 6186 |
| RNF4 | 6265 |
| TRIM9 | 6268 |
| UBR4 | 6390 |
| UBE2V1 | 6498 |
| PSMB3 | 6513 |
| PSMA1 | 6519 |
| UBE4A | 6526 |
| HERC5 | 6832 |
| RNF217 | 6875 |
| PSMD3 | 6889 |
| ASB18 | 7070 |
| FBXL8 | 7088 |
| ASB4 | 7099 |
| KCTD7 | 7432 |
| FBXL16 | 7509 |
| ELOB | 7624 |
| TRIM71 | 7650 |
| UBA52 | 7910 |
| PSMA3 | 7987 |
| CDC34 | 7992 |
| LNX1 | 8012 |
| PSMC3 | 8087 |
| FBXO17 | 8163 |
| TRIM69 | 9552 |
REACTOME_MUSCLE_CONTRACTION
| 674 | |
|---|---|
| set | REACTOME_MUSCLE_CONTRACTION |
| setSize | 197 |
| pANOVA | 0.00306 |
| s.dist | 0.122 |
| p.adjustANOVA | 0.252 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| ACTC1 | 9623 |
| KCNE3 | 9362 |
| KCNK18 | 9304 |
| MYL2 | 9295 |
| SLN | 9181 |
| FXYD6 | 9086 |
| MYH6 | 9043 |
| TNNT2 | 8804 |
| NPPA | 8718 |
| KCNE4 | 8700 |
| MYL10 | 8658 |
| NPPC | 8611 |
| KCNA5 | 8387 |
| TCAP | 8267 |
| TBX5 | 8265 |
| CACNA2D2 | 8178 |
| DES | 8133 |
| MYL3 | 8085 |
| ATP1B2 | 7979 |
| MYBPC3 | 7917 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ACTC1 | 9623 |
| KCNE3 | 9362 |
| KCNK18 | 9304 |
| MYL2 | 9295 |
| SLN | 9181 |
| FXYD6 | 9086 |
| MYH6 | 9043 |
| TNNT2 | 8804 |
| NPPA | 8718 |
| KCNE4 | 8700 |
| MYL10 | 8658 |
| NPPC | 8611 |
| KCNA5 | 8387 |
| TCAP | 8267 |
| TBX5 | 8265 |
| CACNA2D2 | 8178 |
| DES | 8133 |
| MYL3 | 8085 |
| ATP1B2 | 7979 |
| MYBPC3 | 7917 |
| TNNI3 | 7829 |
| SLC8A3 | 7772 |
| TNNT1 | 7766 |
| KCNJ2 | 7604 |
| SLC8A2 | 7484 |
| FXYD4 | 7399 |
| SCN10A | 7388 |
| TRPC1 | 7340 |
| TRIM72 | 7230 |
| MYL9 | 7018 |
| CACNA1C | 7005 |
| CASQ2 | 6970 |
| ACTN2 | 6952 |
| SCN3A | 6787 |
| KCNK9 | 6713 |
| ACTA1 | 6662 |
| ORAI2 | 6640 |
| KCNK1 | 6618 |
| SORBS1 | 6563 |
| CAMK2A | 6475 |
| KCND3 | 6454 |
| ORAI1 | 6368 |
| ATP2A3 | 6323 |
| KCNK7 | 6220 |
| RYR2 | 6167 |
| ITGB5 | 6148 |
| MYL1 | 6100 |
| FGF12 | 5864 |
| SCN9A | 5855 |
| MYL6 | 5759 |
| CACNA1H | 5752 |
| ATP1A4 | 5636 |
| MYLK | 5622 |
| KCNK16 | 5587 |
| KCNIP2 | 5479 |
| GUCY1A2 | 5476 |
| ALDH2 | 5475 |
| GUCY1A1 | 5070 |
| TNNC2 | 5053 |
| ATP2B4 | 4780 |
| KCNK3 | 4663 |
| CALM1 | 4408 |
| TMOD1 | 4356 |
| SCN5A | 4303 |
| SRI | 4213 |
| SCN8A | 4200 |
| CAMK2B | 4138 |
| TNNI2 | 4116 |
| TPM3 | 3691 |
| NOS1 | 3680 |
| MME | 3675 |
| MYH8 | 3653 |
| TNNC1 | 3584 |
| KCNJ11 | 3556 |
| TLN1 | 3545 |
| FKBP1B | 3490 |
| TPM2 | 3432 |
| TNNT3 | 3360 |
| MYL11 | 3242 |
| GATA4 | 2947 |
| ATP1B3 | 2884 |
| ATP2B2 | 2817 |
| MYBPC2 | 2794 |
| LMOD1 | 2454 |
| KCND2 | 2418 |
| KCNK12 | 2327 |
| KCNIP1 | 2259 |
| FXYD3 | 2254 |
| HIPK2 | 2166 |
| TMOD3 | 2018 |
| ITGA1 | 2014 |
| CACNB2 | 1978 |
| ITPR3 | 1792 |
| WWTR1 | 1726 |
| ATP2B1 | 1500 |
| CACNG6 | 1271 |
| DMPK | 1191 |
| DYSF | 1167 |
| KCNK10 | 1093 |
| KCNK6 | 942 |
| VIM | 695 |
| KCNIP3 | 642 |
| KCNJ4 | 510 |
| MYL12B | 353 |
| SORBS3 | 229 |
| SCN4B | 175 |
| CACNG8 | -52 |
| CACNA1G | -132 |
| TPM1 | -197 |
| MYL7 | -201 |
| RYR3 | -243 |
| ACTA2 | -305 |
| CACNG7 | -517 |
| TTN | -526 |
| ATP1B1 | -611 |
| KCNK17 | -640 |
| SCN3B | -826 |
| ITPR1 | -933 |
| SCN2B | -949 |
| SCN1B | -1017 |
| TRDN | -1023 |
| CASQ1 | -1186 |
| ATP1A1 | -1692 |
| SLC8A1 | -1716 |
| ACTG2 | -1781 |
| KCNK13 | -1907 |
| CALD1 | -1931 |
| ITPR2 | -1996 |
| ATP2A1 | -2146 |
| FXYD7 | -2547 |
| CAMK2D | -2651 |
| MYH11 | -2654 |
| ATP1A3 | -2699 |
| HIPK1 | -2843 |
| TNNI1 | -2854 |
| PAK2 | -2914 |
| NKX2-5 | -2930 |
| RANGRF | -3199 |
| PLN | -3290 |
| CAMK2G | -3421 |
| MYL12A | -3474 |
| SCN11A | -3529 |
| PDE5A | -3713 |
| KAT2B | -3769 |
| KCNIP4 | -3781 |
| CAV3 | -3813 |
| NPR1 | -4078 |
| AKAP9 | -4137 |
| KCNK15 | -4203 |
| FGF14 | -4312 |
| PXN | -4316 |
| MYL5 | -4626 |
| CACNG4 | -4674 |
| KCNH2 | -4717 |
| STIM1 | -4771 |
| KCNK2 | -5223 |
| PRKACA | -5493 |
| PAK1 | -5494 |
| ASPH | -5677 |
| CORIN | -5747 |
| ATP2A2 | -5773 |
| KCNJ14 | -5843 |
| NEB | -5925 |
| CACNA1I | -5982 |
| SCN2A | -6016 |
| KCNJ12 | -6121 |
| ATP1A2 | -6392 |
| ANXA2 | -6503 |
| CES1 | -6565 |
| GUCY1B1 | -6654 |
| KCNQ1 | -6704 |
| TMOD2 | -6768 |
| RYR1 | -7230 |
| KCNK4 | -7237 |
| ABCC9 | -7251 |
| ACTN3 | -7325 |
| MYL6B | -7618 |
| AHCYL1 | -7708 |
| SCN4A | -7789 |
| MYBPC1 | -8204 |
| KCNE1 | -8289 |
| ANXA6 | -8357 |
| SCN1A | -8825 |
| FXYD1 | -8930 |
| SCN7A | -8940 |
| NPR2 | -9520 |
| VCL | -9835 |
| FGF11 | -9890 |
| KCNK5 | -9927 |
| CACNB1 | -10285 |
| MYH3 | -10826 |
| FXYD2 | -10860 |
| MYL4 | -10941 |
| TPM4 | -11038 |
| TMOD4 | -11179 |
| KCNE2 | -11352 |
| ANXA1 | -11455 |
REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS
| 233 | |
|---|---|
| set | REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS |
| setSize | 53 |
| pANOVA | 0.00307 |
| s.dist | -0.235 |
| p.adjustANOVA | 0.252 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| NLRC4 | -11069 |
| MAPK13 | -10900 |
| HMOX1 | -10727 |
| BCL2L1 | -10519 |
| CASP1 | -10218 |
| MAP2K6 | -9860 |
| NOD1 | -9854 |
| CYLD | -9497 |
| NLRP1 | -8896 |
| UBB | -8790 |
| MAPK14 | -8203 |
| UBE2N | -8046 |
| MAP3K7 | -7914 |
| NFKB1 | -7717 |
| TXN | -7590 |
| TXNIP | -7024 |
| CASP9 | -6869 |
| P2RX7 | -6546 |
| RIPK2 | -6072 |
| ITCH | -5751 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| NLRC4 | -11069 |
| MAPK13 | -10900 |
| HMOX1 | -10727 |
| BCL2L1 | -10519 |
| CASP1 | -10218 |
| MAP2K6 | -9860 |
| NOD1 | -9854 |
| CYLD | -9497 |
| NLRP1 | -8896 |
| UBB | -8790 |
| MAPK14 | -8203 |
| UBE2N | -8046 |
| MAP3K7 | -7914 |
| NFKB1 | -7717 |
| TXN | -7590 |
| TXNIP | -7024 |
| CASP9 | -6869 |
| P2RX7 | -6546 |
| RIPK2 | -6072 |
| ITCH | -5751 |
| TAB1 | -5712 |
| APP | -5711 |
| AIM2 | -5239 |
| MAPK11 | -4950 |
| TNFAIP3 | -4408 |
| CHUK | -4283 |
| UBC | -3960 |
| CASP2 | -3387 |
| RPS27A | -3374 |
| MEFV | -3243 |
| SUGT1 | -3153 |
| RELA | -3097 |
| PYCARD | -2753 |
| IRAK2 | -2284 |
| CASP8 | -2260 |
| BIRC2 | -1766 |
| NOD2 | -1669 |
| CASP4 | -1302 |
| NFKB2 | -568 |
| TAB2 | 181 |
| BIRC3 | 435 |
| NLRP3 | 1626 |
| PSTPIP1 | 1841 |
| IKBKB | 2113 |
| PANX1 | 3226 |
| BCL2 | 3392 |
| TRAF6 | 4480 |
| MAPK12 | 5108 |
| CARD9 | 5465 |
| AAMP | 5956 |
| HSP90AB1 | 6061 |
| UBE2V1 | 6498 |
| UBA52 | 7910 |
REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION
| 1636 | |
|---|---|
| set | REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION |
| setSize | 361 |
| pANOVA | 0.0045 |
| s.dist | -0.087 |
| p.adjustANOVA | 0.342 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| S100A8 | -11505 |
| TRIM4 | -11376 |
| FBXO40 | -11353 |
| PDIA3 | -11324 |
| PSMB11 | -11321 |
| SOCS3 | -11181 |
| KEAP1 | -11041 |
| FBXW4 | -10879 |
| S100A9 | -10869 |
| UBE2E3 | -10821 |
| KBTBD7 | -10811 |
| UBE2E1 | -10694 |
| UBE3D | -10617 |
| TRIM21 | -10586 |
| ZNRF1 | -10498 |
| UBE2S | -10441 |
| NPEPPS | -10282 |
| HERC6 | -10276 |
| ASB8 | -10245 |
| PSMB9 | -10214 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| S100A8 | -11505 |
| TRIM4 | -11376 |
| FBXO40 | -11353 |
| PDIA3 | -11324 |
| PSMB11 | -11321 |
| SOCS3 | -11181 |
| KEAP1 | -11041 |
| FBXW4 | -10879 |
| S100A9 | -10869 |
| UBE2E3 | -10821 |
| KBTBD7 | -10811 |
| UBE2E1 | -10694 |
| UBE3D | -10617 |
| TRIM21 | -10586 |
| ZNRF1 | -10498 |
| UBE2S | -10441 |
| NPEPPS | -10282 |
| HERC6 | -10276 |
| ASB8 | -10245 |
| PSMB9 | -10214 |
| PSMA5 | -10194 |
| CALR | -10123 |
| KLHL42 | -10006 |
| TLR1 | -10000 |
| PSMB8 | -9839 |
| FBXL18 | -9827 |
| UBE2J2 | -9795 |
| HACE1 | -9671 |
| FBXO9 | -9601 |
| MEX3C | -9537 |
| RNF34 | -9527 |
| UBE2G1 | -9475 |
| RBX1 | -9464 |
| SEC61A2 | -9399 |
| UBE2D4 | -9310 |
| HLA-A | -9216 |
| UBA6 | -9129 |
| HLA-E | -9018 |
| ASB16 | -9015 |
| FBXO4 | -8966 |
| ASB1 | -8924 |
| CD207 | -8855 |
| UBB | -8790 |
| TAP1 | -8725 |
| ANAPC13 | -8657 |
| TRIM39 | -8616 |
| ANAPC11 | -8493 |
| FBXO32 | -8422 |
| DTX3L | -8410 |
| SEC61A1 | -8402 |
| HERC1 | -8328 |
| PSMB7 | -8319 |
| FBXO10 | -8279 |
| UBE2U | -8274 |
| UBE2H | -8268 |
| NCF2 | -8194 |
| SIAH2 | -8177 |
| PSME1 | -8170 |
| LRRC41 | -8160 |
| RNF7 | -8107 |
| TPP2 | -8091 |
| KBTBD8 | -8064 |
| UBE2N | -8046 |
| VHL | -8019 |
| PSMB6 | -7992 |
| UBE2Q2 | -7895 |
| KLHL22 | -7774 |
| UBE2W | -7697 |
| BTBD6 | -7679 |
| CDC23 | -7642 |
| FBXO15 | -7637 |
| S100A1 | -7543 |
| LRR1 | -7388 |
| ANAPC1 | -7349 |
| FBXW8 | -7200 |
| PSMC4 | -7169 |
| ERAP2 | -7096 |
| KLHL41 | -6993 |
| CUL3 | -6971 |
| HECTD2 | -6964 |
| LMO7 | -6825 |
| FBXL12 | -6609 |
| PSME3 | -6558 |
| ASB5 | -6553 |
| TRAF7 | -6509 |
| UBE2J1 | -6458 |
| KCTD6 | -6437 |
| RNF182 | -6389 |
| RNF138 | -6300 |
| LY96 | -6193 |
| PSMD14 | -6115 |
| B2M | -6084 |
| SEC13 | -6075 |
| LTN1 | -6065 |
| FBXO27 | -6039 |
| TLR6 | -6002 |
| KLHL2 | -5902 |
| LRSAM1 | -5886 |
| PSMA7 | -5868 |
| CDC26 | -5830 |
| FGG | -5755 |
| HMGB1 | -5752 |
| ITCH | -5751 |
| TRIM37 | -5717 |
| PRKN | -5662 |
| LNPEP | -5563 |
| FBXW7 | -5521 |
| HECTD1 | -5410 |
| ASB6 | -5351 |
| TRIM63 | -5341 |
| DZIP3 | -5336 |
| PSMD7 | -5158 |
| SKP2 | -5131 |
| FBXW9 | -5128 |
| UBE2B | -5041 |
| ATG14 | -4911 |
| ITGAV | -4786 |
| KLHL20 | -4769 |
| UBE2R2 | -4758 |
| FBXO2 | -4755 |
| PSMD8 | -4743 |
| HLA-G | -4561 |
| CANX | -4533 |
| UNKL | -4502 |
| FBXW12 | -4352 |
| CHUK | -4283 |
| ANAPC5 | -4281 |
| THOP1 | -4236 |
| PSMD5 | -4189 |
| RNF25 | -4183 |
| HERC2 | -4168 |
| TRIM41 | -4148 |
| TRAIP | -4121 |
| UBE3C | -4068 |
| UBC | -3960 |
| SOCS1 | -3954 |
| PSMD11 | -3936 |
| PSMB2 | -3889 |
| FBXO11 | -3872 |
| ASB10 | -3832 |
| FBXL19 | -3826 |
| SEC24B | -3817 |
| ATG7 | -3780 |
| BTBD1 | -3699 |
| BECN1 | -3543 |
| PSMA6 | -3468 |
| UBE2K | -3457 |
| PSMD9 | -3390 |
| RPS27A | -3374 |
| MRC2 | -3311 |
| SNAP23 | -3277 |
| FBXO21 | -3221 |
| ANAPC7 | -3205 |
| UBE2F | -3128 |
| UBE2Z | -3125 |
| UBE2C | -3089 |
| KLHL5 | -3086 |
| PSME4 | -3068 |
| SEC31A | -3054 |
| CUL7 | -3027 |
| RNF144B | -2944 |
| FBXW10 | -2915 |
| FBXL13 | -2884 |
| FBXL14 | -2881 |
| TRIP12 | -2792 |
| MYLIP | -2774 |
| TAP2 | -2700 |
| FBXL5 | -2667 |
| UBE2O | -2625 |
| UBE2M | -2548 |
| CTSS | -2467 |
| SMURF2 | -2453 |
| SPSB2 | -2445 |
| NEDD4L | -2440 |
| PSMC5 | -2407 |
| ARIH2 | -2357 |
| CUL5 | -2334 |
| ASB3 | -2278 |
| HLA-B | -2277 |
| MGRN1 | -2270 |
| UBE2L6 | -2155 |
| HECW2 | -2109 |
| PSMA2 | -1982 |
| BTRC | -1967 |
| SPSB4 | -1887 |
| RNF115 | -1801 |
| KLHL25 | -1795 |
| FBXL15 | -1767 |
| CUL1 | -1737 |
| FBXO22 | -1717 |
| KLHL11 | -1709 |
| SEC23A | -1691 |
| KLHL3 | -1641 |
| CCNF | -1558 |
| HECTD3 | -1524 |
| PIK3C3 | -1508 |
| FBXO31 | -1492 |
| UBAC1 | -1408 |
| UBR2 | -1351 |
| CBLB | -1241 |
| UBE2Q1 | -1193 |
| LONRF1 | -1149 |
| TRIM36 | -1145 |
| FBXL20 | -1069 |
| UBOX5 | -996 |
| NEDD4 | -968 |
| UBE2D3 | -967 |
| CUL2 | -848 |
| FBXO44 | -824 |
| UBR1 | -697 |
| SEC24A | -669 |
| FBXW11 | -659 |
| PSMB1 | -649 |
| HERC4 | -634 |
| UBE2G2 | -598 |
| SEC22B | -481 |
| UFL1 | -459 |
| PSMC1 | -332 |
| PSMD13 | -227 |
| AREL1 | -51 |
| PSMC6 | 25 |
| MKRN1 | 46 |
| RNF213 | 94 |
| PIK3R4 | 133 |
| PSMD6 | 166 |
| RNF126 | 179 |
| RNF114 | 243 |
| SMURF1 | 283 |
| PJA2 | 299 |
| RNF19A | 315 |
| PSMF1 | 351 |
| PSMD2 | 438 |
| UBE2D1 | 455 |
| TRIM32 | 479 |
| FBXO7 | 727 |
| RBBP6 | 732 |
| ASB17 | 822 |
| PSMB10 | 869 |
| FZR1 | 907 |
| FBXL7 | 1026 |
| UBE2V2 | 1082 |
| ASB15 | 1096 |
| RNF41 | 1099 |
| PSMC2 | 1115 |
| SEC61G | 1117 |
| PSMD1 | 1119 |
| ASB13 | 1225 |
| CTSL | 1302 |
| UBE3B | 1410 |
| ZNRF2 | 1471 |
| SH3RF1 | 1515 |
| UBE3A | 1556 |
| ZBTB16 | 1557 |
| SIAH1 | 1646 |
| RBCK1 | 1694 |
| RNF19B | 1708 |
| UBA7 | 1721 |
| FBXO30 | 1837 |
| TAPBP | 1915 |
| PSME2 | 1954 |
| WSB1 | 1990 |
| UBE2L3 | 2027 |
| ASB14 | 2057 |
| IKBKB | 2113 |
| ASB2 | 2410 |
| WWP1 | 2440 |
| PSMD12 | 2494 |
| FBXL4 | 2504 |
| RCHY1 | 2542 |
| ANAPC10 | 2561 |
| BLMH | 2676 |
| VAMP8 | 2687 |
| ANAPC4 | 2773 |
| SAR1B | 2783 |
| KLHL9 | 2843 |
| RNF123 | 2854 |
| CDC16 | 3095 |
| GAN | 3119 |
| DET1 | 3216 |
| KBTBD6 | 3229 |
| RNF220 | 3332 |
| CDC20 | 3349 |
| DCAF1 | 3391 |
| TRIM11 | 3594 |
| PSMA8 | 3597 |
| FBXW2 | 3630 |
| TRIM50 | 3774 |
| SEM1 | 3801 |
| GLMN | 3820 |
| SEC24D | 3822 |
| UBA5 | 3893 |
| ANAPC2 | 4109 |
| ERAP1 | 4111 |
| PSMB4 | 4183 |
| CYBA | 4195 |
| FBXO41 | 4295 |
| CDC27 | 4326 |
| PSMD4 | 4365 |
| FBXW5 | 4411 |
| RNF6 | 4576 |
| RNF130 | 4582 |
| RNF14 | 4686 |
| UBE2D2 | 4781 |
| STUB1 | 4799 |
| SKP1 | 4805 |
| HERC3 | 4807 |
| ASB7 | 4873 |
| FBXL3 | 4875 |
| HLA-C | 4893 |
| RNF111 | 5062 |
| NCF4 | 5085 |
| TLR4 | 5129 |
| CD36 | 5163 |
| VAMP3 | 5261 |
| SEC24C | 5488 |
| TLR2 | 5585 |
| PSMA4 | 5588 |
| PSMB5 | 5606 |
| UBE2E2 | 5610 |
| STX4 | 5678 |
| FBXO6 | 5996 |
| KLHL21 | 6006 |
| FBXL22 | 6010 |
| UBA3 | 6013 |
| TIRAP | 6033 |
| ELOC | 6137 |
| ITGB5 | 6148 |
| MIB2 | 6161 |
| SPSB1 | 6186 |
| RNF4 | 6265 |
| TRIM9 | 6268 |
| UBR4 | 6390 |
| UBE2V1 | 6498 |
| PSMB3 | 6513 |
| PSMA1 | 6519 |
| UBE4A | 6526 |
| SEC61B | 6733 |
| HERC5 | 6832 |
| RNF217 | 6875 |
| PSMD3 | 6889 |
| ASB18 | 7070 |
| FBXL8 | 7088 |
| ASB4 | 7099 |
| KCTD7 | 7432 |
| FBXL16 | 7509 |
| HLA-F | 7533 |
| ELOB | 7624 |
| TRIM71 | 7650 |
| UBA52 | 7910 |
| CTSV | 7969 |
| PSMA3 | 7987 |
| CDC34 | 7992 |
| LNX1 | 8012 |
| PSMC3 | 8087 |
| FBXO17 | 8163 |
| HSPA5 | 8245 |
| CD14 | 8569 |
| MYD88 | 9085 |
| FGA | 9347 |
| TRIM69 | 9552 |
| FGB | 9603 |
REACTOME_GLUTATHIONE_CONJUGATION
| 147 | |
|---|---|
| set | REACTOME_GLUTATHIONE_CONJUGATION |
| setSize | 33 |
| pANOVA | 0.00458 |
| s.dist | -0.285 |
| p.adjustANOVA | 0.342 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| GSTA5 | -11265 |
| AKR1A1 | -10571 |
| OPLAH | -10208 |
| GSTP1 | -10150 |
| GGCT | -9909 |
| GSTA3 | -9789 |
| GCLC | -9644 |
| MGST3 | -9632 |
| GSTK1 | -8746 |
| CHAC1 | -8595 |
| GSTM4 | -8155 |
| GSTA4 | -7391 |
| MGST1 | -7244 |
| GGT5 | -6531 |
| GSS | -6490 |
| GSTZ1 | -6150 |
| CHAC2 | -5976 |
| GGT6 | -5315 |
| HPGDS | -4210 |
| GGT1 | -3063 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| GSTA5 | -11265 |
| AKR1A1 | -10571 |
| OPLAH | -10208 |
| GSTP1 | -10150 |
| GGCT | -9909 |
| GSTA3 | -9789 |
| GCLC | -9644 |
| MGST3 | -9632 |
| GSTK1 | -8746 |
| CHAC1 | -8595 |
| GSTM4 | -8155 |
| GSTA4 | -7391 |
| MGST1 | -7244 |
| GGT5 | -6531 |
| GSS | -6490 |
| GSTZ1 | -6150 |
| CHAC2 | -5976 |
| GGT6 | -5315 |
| HPGDS | -4210 |
| GGT1 | -3063 |
| GCLM | -3011 |
| GGT7 | -2860 |
| GSTM3 | -2268 |
| GSTO1 | -1511 |
| ESD | -1376 |
| MGST2 | -693 |
| GSTM1 | -487 |
| GSTM2 | 1005 |
| GSTO2 | 5767 |
| CNDP2 | 6856 |
| GSTA1 | 8381 |
| GSTM5 | 8383 |
| GSTA2 | 9984 |
REACTOME_INTRA_GOLGI_AND_RETROGRADE_GOLGI_TO_ER_TRAFFIC
| 1087 | |
|---|---|
| set | REACTOME_INTRA_GOLGI_AND_RETROGRADE_GOLGI_TO_ER_TRAFFIC |
| setSize | 198 |
| pANOVA | 0.00493 |
| s.dist | -0.116 |
| p.adjustANOVA | 0.352 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TUBB8 | -11590 |
| KDELR1 | -11305 |
| KIF3A | -11074 |
| TUBA4A | -10847 |
| CAPZA2 | -10797 |
| MAN1C1 | -10614 |
| TUBB4A | -10582 |
| TMED2 | -10492 |
| ALPP | -10490 |
| RGP1 | -10479 |
| KIF21A | -10449 |
| GOSR1 | -10334 |
| GALNT1 | -10181 |
| DYNLL1 | -10134 |
| COG7 | -10066 |
| KIF20B | -9982 |
| RAB43 | -9794 |
| USP6NL | -9770 |
| KLC1 | -9651 |
| RAB3GAP2 | -9461 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TUBB8 | -11590 |
| KDELR1 | -11305 |
| KIF3A | -11074 |
| TUBA4A | -10847 |
| CAPZA2 | -10797 |
| MAN1C1 | -10614 |
| TUBB4A | -10582 |
| TMED2 | -10492 |
| ALPP | -10490 |
| RGP1 | -10479 |
| KIF21A | -10449 |
| GOSR1 | -10334 |
| GALNT1 | -10181 |
| DYNLL1 | -10134 |
| COG7 | -10066 |
| KIF20B | -9982 |
| RAB43 | -9794 |
| USP6NL | -9770 |
| KLC1 | -9651 |
| RAB3GAP2 | -9461 |
| TUBA4B | -9365 |
| YKT6 | -9333 |
| COG2 | -8908 |
| TGOLN2 | -8867 |
| CAPZA3 | -8856 |
| STX10 | -8778 |
| CENPE | -8742 |
| CYTH3 | -8597 |
| VPS54 | -8403 |
| NAPA | -8332 |
| RAB30 | -8169 |
| COPG1 | -8078 |
| KIF4B | -8005 |
| KIFC2 | -7983 |
| TMED9 | -7847 |
| KLC3 | -7788 |
| DCTN2 | -7699 |
| CYTH4 | -7608 |
| COPB2 | -7408 |
| COPZ1 | -7291 |
| RHOBTB3 | -7283 |
| KIF1C | -7199 |
| ACTR1A | -7122 |
| RACGAP1 | -6926 |
| M6PR | -6780 |
| KDELR2 | -6588 |
| KIF22 | -6478 |
| VPS51 | -6443 |
| PAFAH1B1 | -6379 |
| CUX1 | -6207 |
| NBAS | -5970 |
| KIF5B | -5765 |
| PAFAH1B3 | -5582 |
| MAN1A1 | -5580 |
| USE1 | -5425 |
| COG5 | -5420 |
| TRIP11 | -5350 |
| GOLGA1 | -5349 |
| KIF18A | -5303 |
| KIF1B | -5287 |
| SNAP29 | -5190 |
| CYTH1 | -5185 |
| ARFGAP3 | -5173 |
| RAB6A | -5055 |
| ARL1 | -4891 |
| NAPB | -4820 |
| KIF2B | -4720 |
| RIC1 | -4708 |
| COPB1 | -4689 |
| VPS52 | -4552 |
| PLIN3 | -4542 |
| KIF6 | -4538 |
| ARFRP1 | -4506 |
| KIF2A | -4442 |
| RAB1B | -4395 |
| KIF9 | -4377 |
| KIF13B | -4204 |
| DCTN4 | -4079 |
| TUBA1C | -4053 |
| RAB18 | -3976 |
| DYNC1LI2 | -3917 |
| DYNC1I2 | -3835 |
| KIF21B | -3603 |
| KLC2 | -3596 |
| GALNT2 | -3552 |
| DCTN6 | -3463 |
| KIF23 | -3459 |
| ARF3 | -3409 |
| GBF1 | -3251 |
| DCTN5 | -3071 |
| ARFGAP2 | -2988 |
| MAN2A1 | -2893 |
| KIF1A | -2824 |
| COG1 | -2650 |
| RABEPK | -2641 |
| STX6 | -2638 |
| TUBA3D | -2604 |
| CAPZA1 | -2585 |
| KLC4 | -2552 |
| KIFC1 | -2508 |
| KDELR3 | -2396 |
| GOLGA5 | -2365 |
| RAB36 | -2362 |
| COG4 | -2248 |
| NSF | -2159 |
| KIF25 | -2119 |
| PLA2G6 | -2009 |
| ARFIP2 | -1970 |
| TMF1 | -1909 |
| RINT1 | -1677 |
| DYNC1I1 | -1599 |
| ARF1 | -1577 |
| RAB39A | -1434 |
| SURF4 | -1326 |
| IGF2R | -1310 |
| ARFGAP1 | -1266 |
| KIF16B | -1202 |
| DYNC1H1 | -1161 |
| CAPZB | -1025 |
| GOLGA4 | -970 |
| GCC2 | -876 |
| BICD1 | -850 |
| STX5 | -802 |
| NAA35 | -728 |
| TUBB4B | -641 |
| GCC1 | -626 |
| TMED10 | -585 |
| COG8 | -528 |
| VPS53 | -527 |
| SEC22B | -481 |
| DYNC1LI1 | -283 |
| VTI1A | -232 |
| STX16 | -33 |
| KIF15 | 192 |
| GOSR2 | 228 |
| TUBA1A | 318 |
| SCOC | 533 |
| TUBB3 | 582 |
| ACTR10 | 974 |
| CYTH2 | 1184 |
| RAB3GAP1 | 1266 |
| ZW10 | 1362 |
| TUBA1B | 1730 |
| KIF19 | 1763 |
| KIF3B | 1813 |
| RAB1A | 1846 |
| ARF4 | 1970 |
| STX18 | 2110 |
| VPS45 | 2205 |
| BET1L | 2274 |
| KIF18B | 2318 |
| KIF27 | 2407 |
| COPZ2 | 2581 |
| KIF26A | 2813 |
| ARCN1 | 2823 |
| KIF26B | 2924 |
| NAA30 | 2931 |
| COPG2 | 2943 |
| TUBB2A | 3132 |
| MAN1A2 | 3134 |
| KIF20A | 3416 |
| KIF3C | 3485 |
| TMED3 | 3623 |
| KIFAP3 | 3729 |
| COPE | 3857 |
| TUBAL3 | 3868 |
| COG3 | 3916 |
| KIF2C | 4126 |
| KIF11 | 4363 |
| AGPAT3 | 4416 |
| RAB6B | 4733 |
| COPA | 4736 |
| VAMP4 | 4827 |
| MAN2A2 | 4938 |
| COG6 | 5046 |
| NAA38 | 5236 |
| VAMP3 | 5261 |
| TUBB1 | 5346 |
| NAPG | 5432 |
| GOLIM4 | 5821 |
| BICD2 | 6082 |
| PAFAH1B2 | 6094 |
| TUBA3C | 6217 |
| DCTN1 | 6219 |
| RAB33B | 6369 |
| PLA2G4A | 6436 |
| DCTN3 | 6735 |
| KIF5A | 7357 |
| TMED7 | 7548 |
| TUBB6 | 7617 |
| TUBB2B | 8061 |
| SYS1 | 8396 |
| TUBA3E | 8431 |
| BNIP1 | 8529 |
| TUBA8 | 8640 |
| DYNLL2 | 8677 |
| ARF5 | 9302 |
| KIF12 | 9615 |
REACTOME_NUCLEOTIDE_EXCISION_REPAIR
| 1021 | |
|---|---|
| set | REACTOME_NUCLEOTIDE_EXCISION_REPAIR |
| setSize | 107 |
| pANOVA | 0.0058 |
| s.dist | -0.154 |
| p.adjustANOVA | 0.395 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| SUMO2 | -11339 |
| POLD4 | -11002 |
| SUMO1 | -10728 |
| TCEA1 | -10557 |
| RAD23A | -10503 |
| POLE2 | -10034 |
| HMGN1 | -9990 |
| COPS8 | -9834 |
| ERCC1 | -9751 |
| RBX1 | -9464 |
| XPA | -9331 |
| UBB | -8790 |
| ERCC2 | -8731 |
| RPA2 | -8723 |
| POLR2H | -8504 |
| POLR2G | -8398 |
| ACTR5 | -8153 |
| UBE2N | -8046 |
| YY1 | -8000 |
| CDK7 | -7755 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SUMO2 | -11339 |
| POLD4 | -11002 |
| SUMO1 | -10728 |
| TCEA1 | -10557 |
| RAD23A | -10503 |
| POLE2 | -10034 |
| HMGN1 | -9990 |
| COPS8 | -9834 |
| ERCC1 | -9751 |
| RBX1 | -9464 |
| XPA | -9331 |
| UBB | -8790 |
| ERCC2 | -8731 |
| RPA2 | -8723 |
| POLR2H | -8504 |
| POLR2G | -8398 |
| ACTR5 | -8153 |
| UBE2N | -8046 |
| YY1 | -8000 |
| CDK7 | -7755 |
| COPS3 | -7685 |
| INO80B | -7580 |
| POLE4 | -7226 |
| COPS5 | -7224 |
| CHD1L | -7214 |
| XRCC1 | -7045 |
| POLE | -6849 |
| ZNF830 | -6798 |
| POLR2C | -6628 |
| ERCC5 | -6626 |
| PIAS1 | -6572 |
| COPS2 | -6398 |
| RFC1 | -6180 |
| ACTR8 | -6029 |
| POLD2 | -5763 |
| LIG1 | -5520 |
| POLK | -5451 |
| POLD3 | -5248 |
| PARP2 | -5213 |
| POLR2D | -5181 |
| ELL | -4998 |
| RFC5 | -4967 |
| INO80E | -4929 |
| INO80D | -4919 |
| GTF2H4 | -4904 |
| SUMO3 | -4903 |
| NFRKB | -4865 |
| PIAS3 | -4835 |
| GTF2H3 | -4677 |
| INO80C | -4596 |
| GPS1 | -4125 |
| UBC | -3960 |
| RAD23B | -3896 |
| POLR2B | -3686 |
| INO80 | -3377 |
| RPS27A | -3374 |
| ERCC4 | -3337 |
| PRPF19 | -3100 |
| GTF2H5 | -3048 |
| MCRS1 | -2817 |
| POLR2L | -2674 |
| RPA3 | -2234 |
| RPA1 | -1871 |
| COPS6 | -1833 |
| ERCC8 | -1263 |
| USP45 | -1038 |
| AQR | -818 |
| COPS7A | -756 |
| POLE3 | -631 |
| DDB1 | -236 |
| RUVBL1 | -127 |
| RFC3 | 262 |
| PPIE | 429 |
| RFC2 | 597 |
| XAB2 | 613 |
| POLR2A | 915 |
| ACTL6A | 1044 |
| DDB2 | 1053 |
| UBE2V2 | 1082 |
| XPC | 1155 |
| CCNH | 1898 |
| POLD1 | 1996 |
| POLR2I | 2278 |
| ERCC3 | 3005 |
| PCNA | 3188 |
| USP7 | 3204 |
| UVSSA | 3361 |
| CUL4A | 3629 |
| POLR2E | 3770 |
| LIG3 | 3968 |
| COPS4 | 4123 |
| RFC4 | 4373 |
| ISY1 | 4652 |
| EP300 | 4777 |
| RNF111 | 5062 |
| MNAT1 | 5269 |
| TFPT | 5608 |
| ERCC6 | 5702 |
| COPS7B | 5746 |
| ACTB | 6012 |
| GTF2H1 | 6412 |
| POLR2F | 6499 |
| POLR2K | 6527 |
| UBE2I | 7197 |
| UBA52 | 7910 |
| PARP1 | 9425 |
| POLR2J | 10148 |
REACTOME_SODIUM_CALCIUM_EXCHANGERS
| 731 | |
|---|---|
| set | REACTOME_SODIUM_CALCIUM_EXCHANGERS |
| setSize | 11 |
| pANOVA | 0.00601 |
| s.dist | 0.478 |
| p.adjustANOVA | 0.395 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| SLC8A3 | 7772 |
| SLC8A2 | 7484 |
| SLC24A3 | 6744 |
| SLC24A2 | 6489 |
| SLC24A5 | 6430 |
| CALM1 | 4408 |
| SRI | 4213 |
| SLC24A4 | 3581 |
| SLC8B1 | 1815 |
| SLC24A1 | 1489 |
| SLC8A1 | -1716 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SLC8A3 | 7772 |
| SLC8A2 | 7484 |
| SLC24A3 | 6744 |
| SLC24A2 | 6489 |
| SLC24A5 | 6430 |
| CALM1 | 4408 |
| SRI | 4213 |
| SLC24A4 | 3581 |
| SLC8B1 | 1815 |
| SLC24A1 | 1489 |
| SLC8A1 | -1716 |
REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS
| 768 | |
|---|---|
| set | REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS |
| setSize | 18 |
| pANOVA | 0.00857 |
| s.dist | 0.358 |
| p.adjustANOVA | 0.541 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| SLC6A19 | 8238 |
| SLC18A2 | 7991 |
| SLC6A5 | 7444 |
| SLC6A3 | 7006 |
| SLC6A20 | 6966 |
| SLC18A1 | 6434 |
| SLC6A1 | 6228 |
| SLC6A9 | 4884 |
| SLC6A7 | 3656 |
| SLC6A18 | 3589 |
| SLC6A13 | 3185 |
| SLC6A2 | 1560 |
| SLC6A12 | 1466 |
| SLC22A2 | -984 |
| SLC6A6 | -1094 |
| SLC6A15 | -2423 |
| SLC6A11 | -3571 |
| SLC22A1 | -4746 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SLC6A19 | 8238 |
| SLC18A2 | 7991 |
| SLC6A5 | 7444 |
| SLC6A3 | 7006 |
| SLC6A20 | 6966 |
| SLC18A1 | 6434 |
| SLC6A1 | 6228 |
| SLC6A9 | 4884 |
| SLC6A7 | 3656 |
| SLC6A18 | 3589 |
| SLC6A13 | 3185 |
| SLC6A2 | 1560 |
| SLC6A12 | 1466 |
| SLC22A2 | -984 |
| SLC6A6 | -1094 |
| SLC6A15 | -2423 |
| SLC6A11 | -3571 |
| SLC22A1 | -4746 |
REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_CASPASE_ACTIVATORS_AND_CASPASES
| 1063 | |
|---|---|
| set | REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_CASPASE_ACTIVATORS_AND_CASPASES |
| setSize | 12 |
| pANOVA | 0.00984 |
| s.dist | -0.43 |
| p.adjustANOVA | 0.57 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| NLRC4 | -11069 |
| CASP1 | -10218 |
| CASP10 | -8326 |
| CRADD | -8248 |
| TP63 | -8220 |
| CASP6 | -7842 |
| PIDD1 | -6903 |
| APAF1 | -6062 |
| CASP2 | -3387 |
| TP73 | -2878 |
| ATM | 63 |
| TP53 | 6303 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| NLRC4 | -11069 |
| CASP1 | -10218 |
| CASP10 | -8326 |
| CRADD | -8248 |
| TP63 | -8220 |
| CASP6 | -7842 |
| PIDD1 | -6903 |
| APAF1 | -6062 |
| CASP2 | -3387 |
| TP73 | -2878 |
| ATM | 63 |
| TP53 | 6303 |
REACTOME_AFLATOXIN_ACTIVATION_AND_DETOXIFICATION
| 877 | |
|---|---|
| set | REACTOME_AFLATOXIN_ACTIVATION_AND_DETOXIFICATION |
| setSize | 19 |
| pANOVA | 0.00989 |
| s.dist | -0.342 |
| p.adjustANOVA | 0.57 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| DPEP3 | -11300 |
| DPEP1 | -11258 |
| ACY3 | -10767 |
| CYP3A4 | -9633 |
| MGST3 | -9632 |
| AKR7A3 | -8123 |
| MGST1 | -7244 |
| GGT5 | -6531 |
| AKR7L | -6391 |
| GGT6 | -5315 |
| ACY1 | -3807 |
| GGT1 | -3063 |
| GGT7 | -2860 |
| CYP3A5 | -991 |
| MGST2 | -693 |
| AKR7A2 | -441 |
| CYP1A2 | 469 |
| DPEP2 | 2333 |
| CYP2A13 | 8018 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| DPEP3 | -11300 |
| DPEP1 | -11258 |
| ACY3 | -10767 |
| CYP3A4 | -9633 |
| MGST3 | -9632 |
| AKR7A3 | -8123 |
| MGST1 | -7244 |
| GGT5 | -6531 |
| AKR7L | -6391 |
| GGT6 | -5315 |
| ACY1 | -3807 |
| GGT1 | -3063 |
| GGT7 | -2860 |
| CYP3A5 | -991 |
| MGST2 | -693 |
| AKR7A2 | -441 |
| CYP1A2 | 469 |
| DPEP2 | 2333 |
| CYP2A13 | 8018 |
REACTOME_METABOLISM_OF_LIPIDS
| 880 | |
|---|---|
| set | REACTOME_METABOLISM_OF_LIPIDS |
| setSize | 709 |
| pANOVA | 0.0101 |
| s.dist | -0.0567 |
| p.adjustANOVA | 0.57 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| ACOT6 | -11697 |
| PLA2G2A | -11635 |
| CYP4F2 | -11632 |
| THEM5 | -11617 |
| GPAT2 | -11611 |
| GPX2 | -11510 |
| SLC27A5 | -11398 |
| ALDH3B2 | -11389 |
| HSD17B3 | -11344 |
| BCHE | -11341 |
| SUMO2 | -11339 |
| STARD6 | -11314 |
| ABHD3 | -11302 |
| DPEP3 | -11300 |
| CYP2J2 | -11290 |
| PTGDS | -11284 |
| DPEP1 | -11258 |
| CYP7A1 | -11138 |
| ETNPPL | -11106 |
| CYP4F3 | -11093 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ACOT6 | -11697 |
| PLA2G2A | -11635 |
| CYP4F2 | -11632 |
| THEM5 | -11617 |
| GPAT2 | -11611 |
| GPX2 | -11510 |
| SLC27A5 | -11398 |
| ALDH3B2 | -11389 |
| HSD17B3 | -11344 |
| BCHE | -11341 |
| SUMO2 | -11339 |
| STARD6 | -11314 |
| ABHD3 | -11302 |
| DPEP3 | -11300 |
| CYP2J2 | -11290 |
| PTGDS | -11284 |
| DPEP1 | -11258 |
| CYP7A1 | -11138 |
| ETNPPL | -11106 |
| CYP4F3 | -11093 |
| AGT | -11085 |
| CYP21A2 | -11033 |
| ACADVL | -11031 |
| HSD3B2 | -11000 |
| GLIPR1 | -10945 |
| HMGCR | -10938 |
| MORC2 | -10928 |
| GDPD3 | -10865 |
| HMGCS2 | -10817 |
| SUMF2 | -10751 |
| NEU3 | -10750 |
| AKR1C2 | -10722 |
| PLA2G4C | -10687 |
| AGPAT2 | -10653 |
| SLCO1A2 | -10588 |
| MED10 | -10543 |
| PCCB | -10506 |
| CPNE7 | -10461 |
| TECRL | -10452 |
| ELOVL1 | -10446 |
| MECR | -10406 |
| ALOX15 | -10399 |
| INSIG2 | -10393 |
| HSD3B7 | -10364 |
| ACOT13 | -10357 |
| ORMDL3 | -10326 |
| PLA2G5 | -10283 |
| ACAD10 | -10215 |
| ALDH3B1 | -10213 |
| ACOT4 | -10190 |
| MTMR4 | -10111 |
| PECR | -10056 |
| HSD17B12 | -10041 |
| PLPP1 | -10014 |
| PNPLA2 | -10013 |
| NDUFAB1 | -9989 |
| PLA2G10 | -9942 |
| MOGAT3 | -9918 |
| ACOX2 | -9831 |
| PHOSPHO1 | -9819 |
| MTMR2 | -9814 |
| SPHK2 | -9790 |
| ACER1 | -9739 |
| CYP11B2 | -9723 |
| ACHE | -9707 |
| PLAAT3 | -9690 |
| SPTLC2 | -9679 |
| GDE1 | -9639 |
| CYP3A4 | -9633 |
| HSD17B11 | -9617 |
| ELOVL4 | -9595 |
| MBTPS1 | -9589 |
| AMACR | -9444 |
| SCD | -9415 |
| SYNJ1 | -9410 |
| PIK3R2 | -9400 |
| GDPD1 | -9389 |
| CYP2C8 | -9343 |
| VAPA | -9336 |
| PLA2G1B | -9327 |
| PHYH | -9282 |
| SLC25A17 | -9219 |
| THRAP3 | -9217 |
| HMGCS1 | -9158 |
| PI4K2A | -9065 |
| CHPT1 | -9038 |
| NR1H2 | -9028 |
| NCOA2 | -8959 |
| APOA1 | -8926 |
| CYP2C19 | -8891 |
| CYP4F8 | -8851 |
| LIPE | -8836 |
| PLD6 | -8763 |
| SQLE | -8695 |
| PPT1 | -8608 |
| CARM1 | -8567 |
| CHD9 | -8549 |
| CERK | -8533 |
| APOA2 | -8526 |
| FDX1 | -8518 |
| HSD17B13 | -8507 |
| CYP4F22 | -8484 |
| GPAT4 | -8474 |
| LIPH | -8423 |
| MTF1 | -8255 |
| HSD17B8 | -8234 |
| DBI | -8207 |
| FDX2 | -8200 |
| SMPD1 | -8163 |
| GSTM4 | -8155 |
| PNPLA5 | -8140 |
| GBA1 | -8119 |
| SELENOI | -8103 |
| PMVK | -8094 |
| G0S2 | -8013 |
| AKR1B15 | -7998 |
| OXCT1 | -7957 |
| SP1 | -7936 |
| OSBP | -7906 |
| ACER2 | -7888 |
| SPTLC1 | -7827 |
| SGMS1 | -7786 |
| HMGCL | -7759 |
| SMPD2 | -7692 |
| ECI1 | -7678 |
| PLAAT5 | -7670 |
| GPD1 | -7657 |
| MED13 | -7567 |
| INPP5J | -7501 |
| ALOX12B | -7436 |
| PPT2 | -7371 |
| TM7SF2 | -7337 |
| FITM2 | -7331 |
| FABP7 | -7322 |
| HAO2 | -7306 |
| PRXL2B | -7295 |
| GNPAT | -7285 |
| CERS4 | -7231 |
| ESYT1 | -7229 |
| LPIN2 | -7222 |
| TECR | -7176 |
| CPT1B | -7157 |
| MTMR3 | -7063 |
| LPCAT4 | -7059 |
| ACOT2 | -7056 |
| ACADL | -7015 |
| SREBF2 | -6976 |
| ETNK1 | -6945 |
| ACACA | -6898 |
| RAN | -6893 |
| SLCO1B1 | -6874 |
| PLA2G3 | -6871 |
| SMARCD3 | -6859 |
| CUBN | -6851 |
| STARD7 | -6829 |
| NEU2 | -6773 |
| SLC25A1 | -6749 |
| ABHD5 | -6657 |
| FADS2 | -6620 |
| APOA5 | -6567 |
| CRAT | -6563 |
| ACOT7 | -6554 |
| CPTP | -6545 |
| GGT5 | -6531 |
| GBA2 | -6524 |
| SRD5A1 | -6513 |
| NUDT7 | -6500 |
| TSPOAP1 | -6492 |
| PI4KA | -6472 |
| RXRB | -6466 |
| FDPS | -6447 |
| CERS2 | -6415 |
| ACBD7 | -6326 |
| HSD17B7 | -6313 |
| ARNT | -6298 |
| MLYCD | -6285 |
| RXRA | -6266 |
| PITPNM2 | -6217 |
| ELOVL6 | -6198 |
| TMEM86B | -6155 |
| CH25H | -6136 |
| ALDH3A2 | -6135 |
| B4GALNT1 | -6040 |
| NPAS2 | -6036 |
| NCOA6 | -6009 |
| PLD2 | -5960 |
| FAR2 | -5936 |
| PIK3R3 | -5912 |
| SLC27A3 | -5895 |
| MED16 | -5892 |
| CPNE1 | -5885 |
| CRLS1 | -5833 |
| CHKA | -5817 |
| LPIN3 | -5803 |
| SLC10A1 | -5796 |
| PTDSS1 | -5787 |
| MTMR14 | -5783 |
| MMAA | -5771 |
| HEXA | -5753 |
| PRKACB | -5745 |
| CDK19 | -5740 |
| GPS2 | -5687 |
| FADS1 | -5655 |
| DECR2 | -5649 |
| STARD10 | -5598 |
| RAB4A | -5571 |
| NR1H4 | -5556 |
| ABCC1 | -5551 |
| AGPAT5 | -5540 |
| DDHD2 | -5539 |
| PRKACA | -5493 |
| PPARA | -5445 |
| CROT | -5409 |
| MED17 | -5402 |
| HDAC3 | -5395 |
| SLC44A2 | -5361 |
| OSBPL2 | -5334 |
| SLC27A1 | -5307 |
| OSBPL8 | -5233 |
| CEPT1 | -5207 |
| ACLY | -5064 |
| PTGS2 | -5030 |
| PITPNB | -4978 |
| MED21 | -4943 |
| LBR | -4939 |
| FA2H | -4931 |
| MED11 | -4908 |
| SLC44A5 | -4882 |
| ACSM3 | -4853 |
| PNPLA7 | -4827 |
| ACOT11 | -4789 |
| CYP39A1 | -4762 |
| PIK3R5 | -4744 |
| PPARGC1A | -4736 |
| PLA1A | -4711 |
| PPP1CC | -4676 |
| CPNE3 | -4657 |
| PPP1CB | -4653 |
| ESYT2 | -4642 |
| ELOVL5 | -4608 |
| PI4KB | -4568 |
| PLIN3 | -4542 |
| OSBPL9 | -4532 |
| PIP4P1 | -4477 |
| INSIG1 | -4468 |
| FITM1 | -4444 |
| ARSB | -4422 |
| INPP5K | -4368 |
| MVD | -4365 |
| NCOR2 | -4363 |
| MED8 | -4341 |
| MVK | -4328 |
| HPGDS | -4210 |
| HSD17B14 | -4170 |
| CYP4B1 | -4065 |
| PRKACG | -4062 |
| SBF2 | -4025 |
| OSBPL10 | -3963 |
| PIK3C2A | -3906 |
| SLC51A | -3892 |
| MED7 | -3885 |
| PIKFYVE | -3881 |
| INPP4B | -3864 |
| SERPINA6 | -3824 |
| SEC24B | -3817 |
| LPGAT1 | -3815 |
| PI4K2B | -3794 |
| SMPD3 | -3764 |
| OLAH | -3760 |
| CLOCK | -3750 |
| PCTP | -3745 |
| PTGES | -3734 |
| PPARG | -3730 |
| MED23 | -3728 |
| FASN | -3711 |
| PLBD1 | -3704 |
| ECI2 | -3660 |
| TGS1 | -3648 |
| PIK3R1 | -3634 |
| SLC51B | -3620 |
| GC | -3502 |
| PLEKHA4 | -3500 |
| PTGES3 | -3496 |
| NEU1 | -3479 |
| VAPB | -3441 |
| ACSL5 | -3431 |
| ACSBG1 | -3415 |
| ARF3 | -3409 |
| TSPO | -3373 |
| CBR4 | -3341 |
| NFYA | -3313 |
| PTGR2 | -3268 |
| HACD3 | -3261 |
| LPCAT3 | -3223 |
| ACSL3 | -3216 |
| CPT2 | -3212 |
| KPNB1 | -3143 |
| ACACB | -3115 |
| STARD3NL | -3083 |
| PIP4K2B | -3082 |
| SPHK1 | -3075 |
| GGT1 | -3063 |
| RAB5A | -3055 |
| ACADS | -3052 |
| EHHADH | -2978 |
| PCYT2 | -2947 |
| SGPL1 | -2939 |
| HACD2 | -2887 |
| SPNS2 | -2868 |
| DEGS1 | -2851 |
| FAM120B | -2850 |
| CPT1A | -2815 |
| PIK3CB | -2806 |
| ACAT1 | -2794 |
| ACBD5 | -2784 |
| PIP5K1C | -2775 |
| CYP1A1 | -2769 |
| SCAP | -2760 |
| STARD4 | -2750 |
| MCEE | -2728 |
| HADH | -2716 |
| CPNE6 | -2656 |
| TNFRSF21 | -2560 |
| SGPP1 | -2539 |
| MAPKAPK2 | -2537 |
| AHR | -2530 |
| MFSD2A | -2517 |
| IDI1 | -2486 |
| SRD5A2 | -2437 |
| FAAH | -2434 |
| EPHX2 | -2386 |
| HACD1 | -2370 |
| ABCB11 | -2269 |
| TXNRD1 | -2266 |
| LHB | -2264 |
| ACAT2 | -2258 |
| SLC44A1 | -2251 |
| SC5D | -2232 |
| MMUT | -2216 |
| GPX4 | -2172 |
| PTDSS2 | -2134 |
| AKR1C3 | -2123 |
| GDPD5 | -2110 |
| ACOX1 | -2027 |
| PLA2G6 | -2009 |
| ANGPTL4 | -1990 |
| MTMR9 | -1984 |
| PIAS4 | -1981 |
| SLC44A4 | -1972 |
| SGMS2 | -1954 |
| AGPS | -1941 |
| MED31 | -1910 |
| GM2A | -1908 |
| SAMD8 | -1899 |
| NUDT19 | -1885 |
| CSNK2A1 | -1884 |
| PRKD1 | -1849 |
| ABCA1 | -1817 |
| SLC22A5 | -1815 |
| ACOT8 | -1751 |
| TIAM2 | -1750 |
| AKR1B1 | -1742 |
| GPAM | -1711 |
| SEC23A | -1691 |
| ANKRD1 | -1610 |
| PLEKHA2 | -1579 |
| ARF1 | -1577 |
| GLTP | -1576 |
| UGT8 | -1539 |
| PIK3C3 | -1508 |
| MIGA2 | -1484 |
| CYP17A1 | -1421 |
| PITPNM3 | -1410 |
| ARSJ | -1402 |
| CSNK2A2 | -1400 |
| CERT1 | -1398 |
| CYP2U1 | -1396 |
| KDSR | -1379 |
| OSBPL1A | -1375 |
| PIP5K1A | -1335 |
| NRF1 | -1320 |
| CYP51A1 | -1296 |
| PLEKHA1 | -1168 |
| ENPP7 | -1151 |
| LPIN1 | -1087 |
| ORMDL1 | -1073 |
| PLD3 | -1066 |
| HSD17B4 | -1049 |
| MED13L | -1018 |
| BMAL1 | -919 |
| ARSI | -890 |
| ACP6 | -851 |
| CYP2C9 | -844 |
| CYP1B1 | -803 |
| MED1 | -750 |
| ORMDL2 | -736 |
| SEC24A | -669 |
| PLEKHA3 | -660 |
| GPD2 | -608 |
| FAR1 | -577 |
| DDHD1 | -552 |
| MIGA1 | -548 |
| PLA2G2F | -510 |
| LDLRAP1 | -466 |
| HPGD | -461 |
| GGPS1 | -429 |
| BDH1 | -379 |
| ALOX5 | -349 |
| GLB1L | -338 |
| DGAT2 | -317 |
| LSS | -256 |
| SYNJ2 | -251 |
| ACAA2 | -245 |
| AKR1C1 | -137 |
| HACL1 | -133 |
| PLA2G12A | -125 |
| ACAD11 | -79 |
| PRKD2 | -12 |
| PIK3R6 | -11 |
| ACSS3 | 11 |
| PIK3CG | 14 |
| PLEKHA8 | 52 |
| CREBBP | 66 |
| MED24 | 69 |
| PSAP | 108 |
| OSBPL3 | 130 |
| PIK3R4 | 133 |
| ETNK2 | 163 |
| ACSL1 | 167 |
| NCOA1 | 220 |
| PLPP3 | 222 |
| CDIPT | 267 |
| CYP7B1 | 360 |
| ESRRA | 369 |
| PPARD | 379 |
| SIN3A | 397 |
| CYP11B1 | 425 |
| CSNK2B | 434 |
| PTGS1 | 444 |
| PEX11A | 447 |
| CYP1A2 | 469 |
| SREBF1 | 550 |
| MTMR10 | 551 |
| FHL2 | 553 |
| CERS5 | 565 |
| ACBD6 | 569 |
| SLCO1B3 | 577 |
| SUMF1 | 628 |
| CTSA | 663 |
| CYP46A1 | 760 |
| ECHS1 | 848 |
| CERS6 | 899 |
| FDFT1 | 910 |
| PRKAG2 | 962 |
| ABHD4 | 979 |
| MTMR12 | 993 |
| ALOX5AP | 1128 |
| PIK3C2G | 1138 |
| LIPI | 1151 |
| NR1D1 | 1162 |
| THEM4 | 1234 |
| NCOA3 | 1246 |
| CYP24A1 | 1265 |
| FABP12 | 1297 |
| GALC | 1336 |
| MED19 | 1418 |
| PLA2G4E | 1438 |
| ARSG | 1452 |
| PEMT | 1545 |
| DGAT1 | 1578 |
| TBL1XR1 | 1614 |
| PGS1 | 1617 |
| PON2 | 1621 |
| PIP4K2C | 1629 |
| MCAT | 1664 |
| PITPNM1 | 1689 |
| RGL1 | 1701 |
| PLD4 | 1715 |
| CHAT | 1807 |
| ENPP6 | 1831 |
| PTEN | 1836 |
| PIK3CA | 1864 |
| PLA2G4D | 1907 |
| PLIN2 | 1911 |
| NFYC | 2000 |
| ABCB4 | 2007 |
| ABCC3 | 2022 |
| CYP19A1 | 2134 |
| RORA | 2153 |
| SPTSSB | 2160 |
| ALAS1 | 2175 |
| DHCR7 | 2277 |
| DPEP2 | 2333 |
| PNPLA6 | 2343 |
| DHCR24 | 2364 |
| PIK3CD | 2395 |
| MED18 | 2433 |
| HSD11B1 | 2459 |
| TNFAIP8 | 2485 |
| CHKB | 2498 |
| SLC25A20 | 2505 |
| MSMO1 | 2521 |
| MED27 | 2580 |
| TRIB3 | 2690 |
| HILPDA | 2713 |
| PRKAB2 | 2720 |
| PPM1L | 2732 |
| ACBD4 | 2733 |
| SAR1B | 2783 |
| UGT1A9 | 2808 |
| GPCPD1 | 2838 |
| LPCAT1 | 2980 |
| LPCAT2 | 3059 |
| ELOVL2 | 3085 |
| RUFY1 | 3092 |
| ALOX12 | 3155 |
| HELZ2 | 3253 |
| ACADM | 3294 |
| PTPMT1 | 3298 |
| FABP5 | 3303 |
| CSNK1G2 | 3348 |
| ALB | 3438 |
| ACSF2 | 3480 |
| BAAT | 3487 |
| PCYT1A | 3503 |
| PISD | 3558 |
| GLB1 | 3562 |
| ACSL6 | 3719 |
| LCLAT1 | 3741 |
| AACS | 3761 |
| CCNC | 3773 |
| SPTLC3 | 3817 |
| SEC24D | 3822 |
| PLEKHA5 | 3871 |
| PIK3C2B | 3899 |
| CERS3 | 3906 |
| ARSK | 3962 |
| MBOAT2 | 3986 |
| PLPP6 | 3996 |
| MED22 | 4000 |
| PTGR1 | 4002 |
| ACOX3 | 4017 |
| SGPP2 | 4024 |
| PLAAT1 | 4033 |
| RAB14 | 4054 |
| CDK8 | 4058 |
| HEXB | 4073 |
| ALPI | 4108 |
| AGK | 4114 |
| ACOXL | 4141 |
| DECR1 | 4147 |
| SCD5 | 4150 |
| NR1H3 | 4188 |
| AKR1D1 | 4202 |
| PLB1 | 4218 |
| MED4 | 4259 |
| CYP2R1 | 4268 |
| PCCA | 4285 |
| MED29 | 4317 |
| CDS2 | 4319 |
| TBXAS1 | 4343 |
| ARNT2 | 4348 |
| FDXR | 4350 |
| AGPAT4 | 4379 |
| GRHL1 | 4409 |
| SCP2 | 4410 |
| AGPAT3 | 4416 |
| ACSF3 | 4434 |
| FABP9 | 4536 |
| ASAH2 | 4711 |
| ALOXE3 | 4727 |
| EP300 | 4777 |
| SULT2A1 | 4850 |
| CYP4F11 | 4880 |
| SLC10A2 | 4882 |
| ACSM6 | 4889 |
| CYP2E1 | 4908 |
| SLC44A3 | 4912 |
| ACER3 | 4915 |
| MTMR6 | 4926 |
| PON1 | 4937 |
| MOGAT2 | 4960 |
| IDI2 | 4967 |
| PLA2G2D | 5019 |
| UGCG | 5034 |
| PIP4K2A | 5064 |
| PIP5K1B | 5076 |
| B3GALNT1 | 5142 |
| ALOX15B | 5150 |
| CD36 | 5163 |
| ARSA | 5204 |
| HADHA | 5263 |
| CERS1 | 5292 |
| INPP5E | 5312 |
| LTC4S | 5320 |
| NFYB | 5323 |
| SACM1L | 5335 |
| TNFAIP8L3 | 5386 |
| LRP2 | 5409 |
| HADHB | 5478 |
| OSBPL7 | 5483 |
| SEC24C | 5488 |
| ARV1 | 5523 |
| LTA4H | 5548 |
| OSBPL5 | 5568 |
| MTMR7 | 5603 |
| INPP4A | 5707 |
| MED9 | 5750 |
| PNPLA8 | 5769 |
| CYP11A1 | 5777 |
| CAV1 | 5835 |
| SIN3B | 5850 |
| MED28 | 5870 |
| ELOVL3 | 5914 |
| VDR | 5955 |
| CDS1 | 5963 |
| CYP27B1 | 6059 |
| AGMO | 6117 |
| DEGS2 | 6193 |
| SBF1 | 6198 |
| PPARGC1B | 6254 |
| MED20 | 6276 |
| PRKAA2 | 6287 |
| MED25 | 6288 |
| TNFAIP8L1 | 6353 |
| INPPL1 | 6413 |
| MOGAT1 | 6414 |
| PLA2G4A | 6436 |
| FIG4 | 6470 |
| PLEKHA6 | 6503 |
| STAR | 6552 |
| MED30 | 6569 |
| PLA2R1 | 6591 |
| GPD1L | 6675 |
| SPTSSA | 6687 |
| MGLL | 6734 |
| HSD3B1 | 6753 |
| ACSBG2 | 6784 |
| CIDEA | 6805 |
| SMPD4 | 6812 |
| FABP2 | 6876 |
| THRSP | 6892 |
| PTPN13 | 6900 |
| ACAA1 | 6926 |
| PON3 | 6943 |
| NCOR1 | 6969 |
| POMC | 7031 |
| BDH2 | 7133 |
| CYP4A11 | 7179 |
| UBE2I | 7197 |
| CIDEC | 7242 |
| HMGCLL1 | 7281 |
| TNFAIP8L2 | 7317 |
| ME1 | 7353 |
| PLIN1 | 7358 |
| MBOAT7 | 7359 |
| MED15 | 7416 |
| FABP6 | 7458 |
| ASAH1 | 7557 |
| CBR1 | 7567 |
| CYP27A1 | 7585 |
| VAC14 | 7595 |
| INPP5D | 7691 |
| MED6 | 7731 |
| GPX1 | 7792 |
| PLA2G4F | 7839 |
| HSD17B2 | 7861 |
| MBOAT1 | 7865 |
| PRKD3 | 7893 |
| HSD17B1 | 7974 |
| PLD1 | 8058 |
| PLPP2 | 8092 |
| AGPAT1 | 8119 |
| FABP4 | 8147 |
| NEU4 | 8150 |
| CGA | 8227 |
| STARD3 | 8352 |
| PLAAT4 | 8365 |
| OSBPL6 | 8457 |
| ELOVL7 | 8469 |
| DHRS7B | 8486 |
| PLA2G2E | 8593 |
| GK2 | 8600 |
| HACD4 | 8698 |
| HSD11B2 | 8724 |
| AKR1C4 | 8761 |
| ACOT1 | 8822 |
| PTGES2 | 8823 |
| ESYT3 | 8826 |
| PTGIS | 8846 |
| PLA2G15 | 8857 |
| STARD5 | 8896 |
| INPP5F | 8931 |
| TPTE2 | 8937 |
| MED26 | 8983 |
| SRD5A3 | 9148 |
| FABP1 | 9256 |
| PPP1CA | 9335 |
| LGMN | 9338 |
| SLC27A2 | 9377 |
| CYP2D6 | 9466 |
| PLAAT2 | 9487 |
| PNPLA3 | 9502 |
| CYP4A22 | 9614 |
| ACOT12 | 9624 |
| TPTE | 9669 |
| FABP3 | 9683 |
| PLA2G4B | 9720 |
| CYP8B1 | 9812 |
REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_GENE_EXPRESSION
| 94 | |
|---|---|
| set | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_GENE_EXPRESSION |
| setSize | 26 |
| pANOVA | 0.0108 |
| s.dist | -0.289 |
| p.adjustANOVA | 0.59 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| AVP | -11350 |
| BHLHE40 | -9338 |
| NCOA2 | -8959 |
| CARM1 | -8567 |
| CHD9 | -8549 |
| SERPINE1 | -8509 |
| KLF15 | -7948 |
| BMAL2 | -7258 |
| SMARCD3 | -6859 |
| BHLHE41 | -6444 |
| RXRA | -6266 |
| NPAS2 | -6036 |
| NCOA6 | -6009 |
| PPARA | -5445 |
| NAMPT | -4004 |
| CLOCK | -3750 |
| TGS1 | -3648 |
| DBP | -1975 |
| BMAL1 | -919 |
| MED1 | -750 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| AVP | -11350 |
| BHLHE40 | -9338 |
| NCOA2 | -8959 |
| CARM1 | -8567 |
| CHD9 | -8549 |
| SERPINE1 | -8509 |
| KLF15 | -7948 |
| BMAL2 | -7258 |
| SMARCD3 | -6859 |
| BHLHE41 | -6444 |
| RXRA | -6266 |
| NPAS2 | -6036 |
| NCOA6 | -6009 |
| PPARA | -5445 |
| NAMPT | -4004 |
| CLOCK | -3750 |
| TGS1 | -3648 |
| DBP | -1975 |
| BMAL1 | -919 |
| MED1 | -750 |
| CREBBP | 66 |
| NCOA1 | 220 |
| TBL1XR1 | 1614 |
| HELZ2 | 3253 |
| NOCT | 4592 |
| F7 | 8629 |
REACTOME_SUMO_IS_PROTEOLYTICALLY_PROCESSED
| 543 | |
|---|---|
| set | REACTOME_SUMO_IS_PROTEOLYTICALLY_PROCESSED |
| setSize | 6 |
| pANOVA | 0.0114 |
| s.dist | -0.596 |
| p.adjustANOVA | 0.604 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| SUMO2 | -11339 |
| SUMO1 | -10728 |
| SENP5 | -10531 |
| SENP2 | -6784 |
| SUMO3 | -4903 |
| SENP1 | -75 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SUMO2 | -11339 |
| SUMO1 | -10728 |
| SENP5 | -10531 |
| SENP2 | -6784 |
| SUMO3 | -4903 |
| SENP1 | -75 |
REACTOME_STRIATED_MUSCLE_CONTRACTION
| 653 | |
|---|---|
| set | REACTOME_STRIATED_MUSCLE_CONTRACTION |
| setSize | 35 |
| pANOVA | 0.0118 |
| s.dist | 0.246 |
| p.adjustANOVA | 0.604 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| ACTC1 | 9623 |
| MYL2 | 9295 |
| MYH6 | 9043 |
| TNNT2 | 8804 |
| TCAP | 8267 |
| DES | 8133 |
| MYL3 | 8085 |
| MYBPC3 | 7917 |
| TNNI3 | 7829 |
| TNNT1 | 7766 |
| ACTN2 | 6952 |
| ACTA1 | 6662 |
| MYL1 | 6100 |
| TNNC2 | 5053 |
| TMOD1 | 4356 |
| TNNI2 | 4116 |
| TPM3 | 3691 |
| MYH8 | 3653 |
| TNNC1 | 3584 |
| TPM2 | 3432 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ACTC1 | 9623 |
| MYL2 | 9295 |
| MYH6 | 9043 |
| TNNT2 | 8804 |
| TCAP | 8267 |
| DES | 8133 |
| MYL3 | 8085 |
| MYBPC3 | 7917 |
| TNNI3 | 7829 |
| TNNT1 | 7766 |
| ACTN2 | 6952 |
| ACTA1 | 6662 |
| MYL1 | 6100 |
| TNNC2 | 5053 |
| TMOD1 | 4356 |
| TNNI2 | 4116 |
| TPM3 | 3691 |
| MYH8 | 3653 |
| TNNC1 | 3584 |
| TPM2 | 3432 |
| TNNT3 | 3360 |
| MYBPC2 | 2794 |
| TMOD3 | 2018 |
| VIM | 695 |
| TPM1 | -197 |
| TTN | -526 |
| TNNI1 | -2854 |
| NEB | -5925 |
| TMOD2 | -6768 |
| ACTN3 | -7325 |
| MYBPC1 | -8204 |
| MYH3 | -10826 |
| MYL4 | -10941 |
| TPM4 | -11038 |
| TMOD4 | -11179 |
REACTOME_GLYCOGEN_STORAGE_DISEASES
| 554 | |
|---|---|
| set | REACTOME_GLYCOGEN_STORAGE_DISEASES |
| setSize | 15 |
| pANOVA | 0.0128 |
| s.dist | -0.371 |
| p.adjustANOVA | 0.611 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| GYS2 | -11156 |
| SLC37A4 | -8981 |
| UBB | -8790 |
| GBE1 | -8718 |
| G6PC3 | -8515 |
| GYG1 | -8407 |
| GAA | -6922 |
| G6PC1 | -6385 |
| PPP1R3C | -4631 |
| GYS1 | -4515 |
| UBC | -3960 |
| RPS27A | -3374 |
| EPM2A | -2413 |
| NHLRC1 | 5140 |
| UBA52 | 7910 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| GYS2 | -11156 |
| SLC37A4 | -8981 |
| UBB | -8790 |
| GBE1 | -8718 |
| G6PC3 | -8515 |
| GYG1 | -8407 |
| GAA | -6922 |
| G6PC1 | -6385 |
| PPP1R3C | -4631 |
| GYS1 | -4515 |
| UBC | -3960 |
| RPS27A | -3374 |
| EPM2A | -2413 |
| NHLRC1 | 5140 |
| UBA52 | 7910 |
REACTOME_GLUTATHIONE_SYNTHESIS_AND_RECYCLING
| 251 | |
|---|---|
| set | REACTOME_GLUTATHIONE_SYNTHESIS_AND_RECYCLING |
| setSize | 12 |
| pANOVA | 0.0128 |
| s.dist | -0.415 |
| p.adjustANOVA | 0.611 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| OPLAH | -10208 |
| GGCT | -9909 |
| GCLC | -9644 |
| CHAC1 | -8595 |
| GGT5 | -6531 |
| GSS | -6490 |
| CHAC2 | -5976 |
| GGT6 | -5315 |
| GGT1 | -3063 |
| GCLM | -3011 |
| GGT7 | -2860 |
| CNDP2 | 6856 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| OPLAH | -10208 |
| GGCT | -9909 |
| GCLC | -9644 |
| CHAC1 | -8595 |
| GGT5 | -6531 |
| GSS | -6490 |
| CHAC2 | -5976 |
| GGT6 | -5315 |
| GGT1 | -3063 |
| GCLM | -3011 |
| GGT7 | -2860 |
| CNDP2 | 6856 |
REACTOME_NEDDYLATION
| 1308 | |
|---|---|
| set | REACTOME_NEDDYLATION |
| setSize | 235 |
| pANOVA | 0.0131 |
| s.dist | -0.094 |
| p.adjustANOVA | 0.611 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CISH | -11365 |
| FBXO40 | -11353 |
| PSMB11 | -11321 |
| SOCS3 | -11181 |
| KEAP1 | -11041 |
| FBXW4 | -10879 |
| KBTBD7 | -10811 |
| COMMD3 | -10370 |
| ASB8 | -10245 |
| WSB2 | -10237 |
| PSMB9 | -10214 |
| PSMA5 | -10194 |
| KLHL42 | -10006 |
| COMMD7 | -9879 |
| PSMB8 | -9839 |
| COPS8 | -9834 |
| FBXL18 | -9827 |
| FBXO9 | -9601 |
| RBX1 | -9464 |
| DPP3 | -9298 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CISH | -11365 |
| FBXO40 | -11353 |
| PSMB11 | -11321 |
| SOCS3 | -11181 |
| KEAP1 | -11041 |
| FBXW4 | -10879 |
| KBTBD7 | -10811 |
| COMMD3 | -10370 |
| ASB8 | -10245 |
| WSB2 | -10237 |
| PSMB9 | -10214 |
| PSMA5 | -10194 |
| KLHL42 | -10006 |
| COMMD7 | -9879 |
| PSMB8 | -9839 |
| COPS8 | -9834 |
| FBXL18 | -9827 |
| FBXO9 | -9601 |
| RBX1 | -9464 |
| DPP3 | -9298 |
| DCAF17 | -9162 |
| ASB16 | -9015 |
| FBXO4 | -8966 |
| ASB1 | -8924 |
| UBB | -8790 |
| FBXO32 | -8422 |
| SOCS2 | -8373 |
| PSMB7 | -8319 |
| FBXO10 | -8279 |
| PSME1 | -8170 |
| LRRC41 | -8160 |
| RNF7 | -8107 |
| KBTBD8 | -8064 |
| VHL | -8019 |
| PSMB6 | -7992 |
| SENP8 | -7927 |
| ANKRD9 | -7781 |
| KLHL22 | -7774 |
| COPS3 | -7685 |
| BTBD6 | -7679 |
| PUM2 | -7675 |
| FBXO15 | -7637 |
| LRR1 | -7388 |
| CDKN1A | -7378 |
| DCUN1D1 | -7352 |
| NAE1 | -7333 |
| SOCS5 | -7311 |
| COPS5 | -7224 |
| FBXW8 | -7200 |
| PSMC4 | -7169 |
| FEM1B | -7147 |
| COMMD4 | -7110 |
| KLHL41 | -6993 |
| CUL3 | -6971 |
| LMO7 | -6825 |
| FBXL12 | -6609 |
| COP1 | -6566 |
| PSME3 | -6558 |
| ASB5 | -6553 |
| KCTD6 | -6437 |
| COPS2 | -6398 |
| PSMD14 | -6115 |
| FBXO27 | -6039 |
| KLHL2 | -5902 |
| PSMA7 | -5868 |
| DCAF10 | -5801 |
| FBXW7 | -5521 |
| DCAF4 | -5422 |
| ASB6 | -5351 |
| PSMD7 | -5158 |
| SKP2 | -5131 |
| FBXW9 | -5128 |
| KLHL20 | -4769 |
| FBXO2 | -4755 |
| PSMD8 | -4743 |
| NUB1 | -4735 |
| BRCA1 | -4551 |
| FBXW12 | -4352 |
| VCP | -4221 |
| WDR5 | -4199 |
| PSMD5 | -4189 |
| COMMD6 | -4135 |
| NEURL2 | -4126 |
| GPS1 | -4125 |
| UBC | -3960 |
| PSMD11 | -3936 |
| PSMB2 | -3889 |
| FBXO11 | -3872 |
| ASB10 | -3832 |
| FBXL19 | -3826 |
| NFE2L2 | -3768 |
| CUL9 | -3737 |
| BTBD1 | -3699 |
| DCAF5 | -3695 |
| RBBP5 | -3535 |
| PSMA6 | -3468 |
| PSMD9 | -3390 |
| RPS27A | -3374 |
| FBXO21 | -3221 |
| UBE2F | -3128 |
| COMMD8 | -3094 |
| KLHL5 | -3086 |
| PSME4 | -3068 |
| CUL7 | -3027 |
| DCAF13 | -3012 |
| DDA1 | -3008 |
| COMMD9 | -2948 |
| FBXW10 | -2915 |
| FBXL13 | -2884 |
| EPAS1 | -2883 |
| FBXL14 | -2881 |
| FBXL5 | -2667 |
| UBE2M | -2548 |
| SPSB2 | -2445 |
| PSMC5 | -2407 |
| BIRC5 | -2374 |
| CUL5 | -2334 |
| ASB3 | -2278 |
| PSMA2 | -1982 |
| BTRC | -1967 |
| SPSB4 | -1887 |
| COPS6 | -1833 |
| KLHL25 | -1795 |
| FBXL15 | -1767 |
| CUL1 | -1737 |
| FBXO22 | -1717 |
| KLHL11 | -1709 |
| KLHL3 | -1641 |
| PALB2 | -1611 |
| DCAF7 | -1598 |
| CCNF | -1558 |
| FBXO31 | -1492 |
| COMMD1 | -1386 |
| CAND1 | -1292 |
| ERCC8 | -1263 |
| COMMD5 | -1172 |
| WDTC1 | -1142 |
| FBXL20 | -1069 |
| UBE2D3 | -967 |
| CUL2 | -848 |
| FBXO44 | -824 |
| COPS7A | -756 |
| FBXW11 | -659 |
| PSMB1 | -649 |
| DCUN1D2 | -489 |
| PSMC1 | -332 |
| DDB1 | -236 |
| PSMD13 | -227 |
| HIF1A | -30 |
| FEM1C | 0 |
| PSMC6 | 25 |
| PSMD6 | 166 |
| PSMF1 | 351 |
| PSMD2 | 438 |
| UBE2D1 | 455 |
| SQSTM1 | 674 |
| FBXO7 | 727 |
| ASB17 | 822 |
| PSMB10 | 869 |
| FBXL7 | 1026 |
| DDB2 | 1053 |
| ASB15 | 1096 |
| PSMC2 | 1115 |
| PSMD1 | 1119 |
| NEDD8 | 1171 |
| ASB13 | 1225 |
| UCHL3 | 1241 |
| DCUN1D3 | 1531 |
| ZBTB16 | 1557 |
| TULP4 | 1781 |
| FBXO30 | 1837 |
| PSME2 | 1954 |
| WSB1 | 1990 |
| MUL1 | 2005 |
| NPLOC4 | 2017 |
| ASB14 | 2057 |
| ASB2 | 2410 |
| PSMD12 | 2494 |
| FBXL4 | 2504 |
| UBD | 2750 |
| KLHL9 | 2843 |
| UFD1 | 2888 |
| DCAF6 | 2918 |
| GAN | 3119 |
| KBTBD6 | 3229 |
| FEM1A | 3318 |
| PSMA8 | 3597 |
| COMMD2 | 3611 |
| CUL4A | 3629 |
| FBXW2 | 3630 |
| SEM1 | 3801 |
| DCUN1D5 | 3848 |
| UBXN7 | 3927 |
| DCUN1D4 | 3989 |
| COPS4 | 4123 |
| DCAF11 | 4162 |
| PSMB4 | 4183 |
| FBXO41 | 4295 |
| PSMD4 | 4365 |
| FBXW5 | 4411 |
| UBE2D2 | 4781 |
| SKP1 | 4805 |
| SPSB3 | 4829 |
| HIF3A | 4871 |
| ASB7 | 4873 |
| FBXL3 | 4875 |
| DCAF8 | 5097 |
| PSMA4 | 5588 |
| PSMB5 | 5606 |
| COPS7B | 5746 |
| DTL | 5775 |
| FBXO6 | 5996 |
| KLHL21 | 6006 |
| FBXL22 | 6010 |
| UBA3 | 6013 |
| ELOC | 6137 |
| COMMD10 | 6157 |
| SPSB1 | 6186 |
| PSMB3 | 6513 |
| PSMA1 | 6519 |
| PSMD3 | 6889 |
| ASB18 | 7070 |
| FBXL8 | 7088 |
| ASB4 | 7099 |
| KCTD7 | 7432 |
| FBXL16 | 7509 |
| ELOB | 7624 |
| OBSL1 | 7846 |
| UBA52 | 7910 |
| PSMA3 | 7987 |
| DCAF16 | 8014 |
| PSMC3 | 8087 |
| FBXO17 | 8163 |
| SOCS6 | 9276 |
| CCDC8 | 9701 |
REACTOME_NEURONAL_SYSTEM
| 34 | |
|---|---|
| set | REACTOME_NEURONAL_SYSTEM |
| setSize | 388 |
| pANOVA | 0.0137 |
| s.dist | 0.0729 |
| p.adjustANOVA | 0.611 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| GNGT2 | 10053 |
| HTR3D | 9979 |
| KCNMB1 | 9518 |
| GNAI2 | 9357 |
| KCNK18 | 9304 |
| GABRR2 | 9232 |
| KCNJ3 | 8793 |
| KCNH7 | 8732 |
| TUBA8 | 8640 |
| PRKAG3 | 8602 |
| GRM1 | 8496 |
| TUBA3E | 8431 |
| KCNA5 | 8387 |
| GLRA3 | 8269 |
| KCNA1 | 8206 |
| CACNA2D2 | 8178 |
| CHRNA3 | 8134 |
| RASGRF1 | 8097 |
| SLC32A1 | 8095 |
| TUBB2B | 8061 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| GNGT2 | 10053 |
| HTR3D | 9979 |
| KCNMB1 | 9518 |
| GNAI2 | 9357 |
| KCNK18 | 9304 |
| GABRR2 | 9232 |
| KCNJ3 | 8793 |
| KCNH7 | 8732 |
| TUBA8 | 8640 |
| PRKAG3 | 8602 |
| GRM1 | 8496 |
| TUBA3E | 8431 |
| KCNA5 | 8387 |
| GLRA3 | 8269 |
| KCNA1 | 8206 |
| CACNA2D2 | 8178 |
| CHRNA3 | 8134 |
| RASGRF1 | 8097 |
| SLC32A1 | 8095 |
| TUBB2B | 8061 |
| SLC18A2 | 7991 |
| CACNB3 | 7881 |
| KCNJ5 | 7808 |
| SLITRK5 | 7711 |
| GABRR1 | 7625 |
| TUBB6 | 7617 |
| KCNJ2 | 7604 |
| KCNMA1 | 7468 |
| CHRNA1 | 7442 |
| GRIN3A | 7368 |
| HRAS | 7211 |
| ABCC8 | 7051 |
| SLC6A3 | 7006 |
| KCNJ1 | 6958 |
| ACTN2 | 6952 |
| HOMER2 | 6890 |
| SLC1A3 | 6867 |
| MAPK3 | 6757 |
| KCNK9 | 6713 |
| CHRNA4 | 6700 |
| NEFL | 6652 |
| GABRB2 | 6633 |
| KCNK1 | 6618 |
| GNB1 | 6594 |
| GABRR3 | 6592 |
| CAMK2A | 6475 |
| ADCY5 | 6465 |
| KCNN2 | 6462 |
| KCND3 | 6454 |
| GABRA4 | 6301 |
| HOMER1 | 6291 |
| PRKAA2 | 6287 |
| GABRA1 | 6267 |
| NRXN2 | 6259 |
| SLC6A1 | 6228 |
| KCNK7 | 6220 |
| TUBA3C | 6217 |
| HTR3C | 6214 |
| CACNG2 | 6151 |
| KCNC1 | 6124 |
| KCNN3 | 6106 |
| GNAI1 | 6083 |
| SYT1 | 6001 |
| COMT | 5995 |
| CHRNB2 | 5974 |
| SLC1A2 | 5909 |
| KCNJ6 | 5885 |
| LIN7A | 5866 |
| GRIN3B | 5865 |
| GLS | 5844 |
| CACNB4 | 5713 |
| LRRTM1 | 5674 |
| PRKAB1 | 5642 |
| GABRB1 | 5617 |
| KCNK16 | 5587 |
| GRIK3 | 5562 |
| LRFN2 | 5545 |
| RTN3 | 5491 |
| ALDH2 | 5475 |
| PICK1 | 5404 |
| PPFIBP1 | 5379 |
| TUBB1 | 5346 |
| HCN2 | 5327 |
| KCNJ10 | 5274 |
| PDLIM5 | 5051 |
| KCNA7 | 4925 |
| GRIN2A | 4923 |
| PLCB1 | 4905 |
| LIN7C | 4787 |
| KCNN4 | 4685 |
| KCNK3 | 4663 |
| SLITRK1 | 4560 |
| CREB1 | 4535 |
| KCNA3 | 4467 |
| PPFIBP2 | 4439 |
| CALM1 | 4408 |
| KCNMB3 | 4402 |
| GNG2 | 4394 |
| CPLX1 | 4392 |
| GABRG2 | 4362 |
| GNG13 | 4355 |
| GJA10 | 4313 |
| HSPA8 | 4201 |
| PRKAR2B | 4163 |
| SYT2 | 4153 |
| CAMK2B | 4138 |
| EPB41L3 | 3941 |
| KCNAB2 | 3924 |
| DBNL | 3923 |
| TUBAL3 | 3868 |
| GNAT3 | 3829 |
| RPS6KA2 | 3816 |
| GABRG3 | 3751 |
| GRIA4 | 3727 |
| DNAJC5 | 3699 |
| PRKCA | 3665 |
| KCNF1 | 3632 |
| CACNA1E | 3627 |
| KCNJ11 | 3556 |
| KCNH8 | 3533 |
| PLCB3 | 3506 |
| GRIN2C | 3497 |
| HCN4 | 3464 |
| GRIP1 | 3446 |
| ADCY6 | 3433 |
| KCNS3 | 3375 |
| SHANK2 | 3352 |
| PANX1 | 3226 |
| GRIK4 | 3213 |
| ADCY9 | 3186 |
| SLC6A13 | 3185 |
| KCNJ8 | 3157 |
| CHRNG | 3154 |
| TUBB2A | 3132 |
| RASGRF2 | 3042 |
| SLC6A4 | 2941 |
| LRRC4B | 2844 |
| KCNH5 | 2818 |
| KCNA4 | 2807 |
| PPFIA4 | 2802 |
| PPFIA1 | 2771 |
| PRKAB2 | 2720 |
| CAMKK2 | 2708 |
| PPM1E | 2652 |
| SLC1A7 | 2648 |
| NRGN | 2629 |
| KCNG3 | 2612 |
| EPB41L5 | 2599 |
| CACNA1B | 2591 |
| GJD2 | 2567 |
| AP2A1 | 2500 |
| LRFN1 | 2491 |
| AP2M1 | 2466 |
| GLRA1 | 2453 |
| KCND2 | 2418 |
| KCNH6 | 2417 |
| LRRC7 | 2386 |
| PDPK1 | 2289 |
| KCNB1 | 2223 |
| GNG11 | 2196 |
| KCNC3 | 2191 |
| KCNC4 | 2144 |
| HCN3 | 2141 |
| GRIK2 | 2075 |
| KCNMB4 | 2072 |
| ADCY8 | 1989 |
| CACNB2 | 1978 |
| NPTN | 1913 |
| KCNN1 | 1886 |
| CHAT | 1807 |
| AKAP5 | 1740 |
| TUBA1B | 1730 |
| GAD2 | 1663 |
| SLC5A7 | 1592 |
| MDM2 | 1514 |
| SLC6A12 | 1466 |
| GRIP2 | 1433 |
| HTR3B | 1337 |
| ADCY4 | 1319 |
| AP2B1 | 1177 |
| KCNK10 | 1093 |
| GRIK1 | 1092 |
| ADCY7 | 992 |
| GAD1 | 970 |
| PRKAG2 | 962 |
| NAAA | 950 |
| KCNK6 | 942 |
| PPFIA2 | 933 |
| ADCY1 | 877 |
| DLGAP1 | 864 |
| MYO6 | 857 |
| KCNC2 | 853 |
| GABBR2 | 677 |
| KCNJ9 | 590 |
| TUBB3 | 582 |
| AP2S1 | 531 |
| KCNJ4 | 510 |
| ERBB4 | 491 |
| SLC18A3 | 483 |
| CACNA2D3 | 440 |
| KCNH3 | 393 |
| GRIN2B | 363 |
| TUBA1A | 318 |
| SLC38A1 | 311 |
| UNC13B | 297 |
| GABBR1 | 239 |
| GNAL | 162 |
| ARL6IP5 | 38 |
| SYN2 | -32 |
| CACNG8 | -52 |
| NRXN3 | -99 |
| ADCY2 | -102 |
| GNGT1 | -114 |
| GNB3 | -122 |
| PRKAA1 | -250 |
| GLS2 | -356 |
| DLG2 | -364 |
| LRRTM3 | -505 |
| GNG5 | -594 |
| PANX2 | -615 |
| BEGAIN | -617 |
| KCNK17 | -640 |
| TUBB4B | -641 |
| KCNJ16 | -755 |
| SYT12 | -805 |
| PTPRD | -932 |
| KCNH4 | -979 |
| SLC22A2 | -984 |
| SLITRK3 | -1045 |
| GNG12 | -1102 |
| GRIA2 | -1127 |
| GLRB | -1223 |
| CHRND | -1260 |
| SYT10 | -1361 |
| NBEA | -1471 |
| NCALD | -1593 |
| KPNA2 | -1606 |
| GNG10 | -1690 |
| AP2A2 | -1773 |
| CHRNA9 | -1776 |
| HTR3E | -1852 |
| MAPT | -1866 |
| KCNK13 | -1907 |
| SHANK1 | -1918 |
| KCNB2 | -1978 |
| CACNG3 | -2017 |
| CHRNE | -2030 |
| GABRA6 | -2142 |
| KCNQ5 | -2148 |
| NRXN1 | -2152 |
| NSF | -2159 |
| PTPRS | -2180 |
| SYT7 | -2198 |
| APBA3 | -2209 |
| KCNV1 | -2292 |
| CHRNA7 | -2301 |
| SLC17A7 | -2392 |
| GRIA1 | -2393 |
| ALDH5A1 | -2476 |
| STXBP1 | -2536 |
| TUBA3D | -2604 |
| CAMK2D | -2651 |
| IL1RAP | -2771 |
| GNAI3 | -2862 |
| KCNJ15 | -2886 |
| EPB41 | -3238 |
| FLOT2 | -3345 |
| GABRA2 | -3396 |
| CAMK2G | -3421 |
| KCNQ4 | -3498 |
| ARHGEF7 | -3549 |
| SLC6A11 | -3571 |
| DLGAP2 | -3573 |
| ADCY3 | -3624 |
| SLC1A1 | -3687 |
| STX1A | -3943 |
| DLGAP4 | -3948 |
| EPB41L2 | -4037 |
| SRC | -4047 |
| TUBA1C | -4053 |
| PRKACG | -4062 |
| EPB41L1 | -4198 |
| LRRTM4 | -4209 |
| KCNAB1 | -4258 |
| PRKAR1B | -4290 |
| SYN3 | -4459 |
| KCNMB2 | -4478 |
| DLG1 | -4490 |
| DLGAP3 | -4510 |
| KCNG2 | -4591 |
| GABRA5 | -4667 |
| CACNG4 | -4674 |
| KCNH2 | -4717 |
| SIPA1L1 | -4731 |
| SLC22A1 | -4746 |
| GNG3 | -4759 |
| CHRNA2 | -4968 |
| NRG1 | -4997 |
| KCNK2 | -5223 |
| KCNH1 | -5332 |
| NLGN1 | -5360 |
| GNG4 | -5388 |
| GRIK5 | -5465 |
| PRKACA | -5493 |
| VAMP2 | -5566 |
| HCN1 | -5629 |
| LRTOMT | -5667 |
| CAMK4 | -5681 |
| PTPRF | -5694 |
| PRKCG | -5710 |
| PRKACB | -5745 |
| KCNJ14 | -5843 |
| GIT1 | -5865 |
| KCNG4 | -5904 |
| KCNA10 | -5926 |
| MAPK1 | -6079 |
| RIMS1 | -6106 |
| KCNJ12 | -6121 |
| HOMER3 | -6125 |
| APBA2 | -6265 |
| CHRNB3 | -6278 |
| SNAP25 | -6279 |
| SLC38A2 | -6280 |
| GRM5 | -6378 |
| PLCB2 | -6460 |
| TSPOAP1 | -6492 |
| PRKCB | -6551 |
| CHRNA6 | -6624 |
| LIN7B | -6651 |
| KCNQ1 | -6704 |
| KIF17 | -6831 |
| GLUL | -6916 |
| KCNS2 | -7003 |
| GABRB3 | -7030 |
| LRRTM2 | -7060 |
| PRKAG1 | -7069 |
| NTRK3 | -7127 |
| KCNQ2 | -7178 |
| CACNA1A | -7223 |
| KCNK4 | -7237 |
| ABCC9 | -7251 |
| KCNV2 | -7317 |
| PRKAR1A | -7361 |
| CAMK1 | -7384 |
| KCNG1 | -7396 |
| GJC1 | -7421 |
| GNB4 | -7626 |
| DLG4 | -7877 |
| SLITRK6 | -7878 |
| SYT9 | -7908 |
| APBA1 | -8033 |
| SHARPIN | -8057 |
| GRIN1 | -8118 |
| KCNQ3 | -8175 |
| RPS6KA1 | -8254 |
| RAC1 | -8501 |
| RAB3A | -8649 |
| FLOT1 | -8656 |
| GNB2 | -8837 |
| KCNA2 | -8854 |
| GNB5 | -8860 |
| CHRNA5 | -8912 |
| KCNAB3 | -9019 |
| GNG7 | -9020 |
| NRAS | -9056 |
| SLC1A6 | -9164 |
| NLGN2 | -9175 |
| TUBA4B | -9365 |
| PPFIA3 | -9388 |
| CHRNB4 | -9556 |
| HTR3A | -9625 |
| ACHE | -9707 |
| CAMKK1 | -9782 |
| GRIN2D | -9832 |
| GNG8 | -9902 |
| PRKAR2A | -9917 |
| LRFN4 | -10039 |
| KRAS | -10121 |
| CACNB1 | -10285 |
| ABAT | -10402 |
| TUBB4A | -10582 |
| PPM1F | -10592 |
| TUBA4A | -10847 |
| LRFN3 | -10921 |
| KCNS1 | -10949 |
| KCNA6 | -11154 |
| BCHE | -11341 |
| TUBB8 | -11590 |
REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING
| 375 | |
|---|---|
| set | REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING |
| setSize | 67 |
| pANOVA | 0.0138 |
| s.dist | -0.174 |
| p.adjustANOVA | 0.611 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| ACBD3 | -10143 |
| CHMP2A | -10054 |
| SORT1 | -9223 |
| FTH1 | -8939 |
| TGOLN2 | -8867 |
| BLOC1S3 | -8822 |
| CPD | -8717 |
| NAPA | -8332 |
| CLINT1 | -8059 |
| AP1M2 | -7850 |
| AP4E1 | -7760 |
| BLOC1S1 | -7612 |
| PICALM | -7427 |
| M6PR | -6780 |
| AP4M1 | -6735 |
| CTSZ | -6514 |
| FTL | -6388 |
| AP1S1 | -6234 |
| SH3D19 | -6185 |
| APP | -5711 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ACBD3 | -10143 |
| CHMP2A | -10054 |
| SORT1 | -9223 |
| FTH1 | -8939 |
| TGOLN2 | -8867 |
| BLOC1S3 | -8822 |
| CPD | -8717 |
| NAPA | -8332 |
| CLINT1 | -8059 |
| AP1M2 | -7850 |
| AP4E1 | -7760 |
| BLOC1S1 | -7612 |
| PICALM | -7427 |
| M6PR | -6780 |
| AP4M1 | -6735 |
| CTSZ | -6514 |
| FTL | -6388 |
| AP1S1 | -6234 |
| SH3D19 | -6185 |
| APP | -5711 |
| VAMP2 | -5566 |
| AP1G1 | -5545 |
| AP1G2 | -5485 |
| DNASE2 | -5347 |
| AP4B1 | -5280 |
| HGS | -4795 |
| SNAPIN | -4739 |
| SNX9 | -4438 |
| AP4S1 | -4407 |
| AP1M1 | -4178 |
| PIK3C2A | -3906 |
| BLOC1S4 | -3445 |
| SNAP23 | -3277 |
| GBF1 | -3251 |
| DNAJC6 | -3147 |
| CLTB | -2762 |
| AP3S1 | -2330 |
| SNX2 | -2031 |
| NECAP1 | -1964 |
| TPD52 | -1939 |
| HIP1R | -1769 |
| ARF1 | -1577 |
| TFRC | -1416 |
| IGF2R | -1310 |
| CLTC | -1126 |
| AP1B1 | -1032 |
| DTNBP1 | -956 |
| SNX5 | -453 |
| TPD52L1 | -344 |
| GOLGB1 | 347 |
| GNS | 893 |
| CLVS1 | 1049 |
| GAK | 1686 |
| TXNDC5 | 1866 |
| PUM1 | 2246 |
| ARRB1 | 2670 |
| VAMP8 | 2687 |
| CLTA | 2780 |
| RAB5C | 2816 |
| SH3GL2 | 2868 |
| HSPA8 | 4201 |
| AP3B1 | 4209 |
| BLOC1S6 | 4644 |
| DNM2 | 5273 |
| STX4 | 5678 |
| AP1S3 | 6802 |
| CLVS2 | 7743 |
REACTOME_GABA_RECEPTOR_ACTIVATION
| 1627 | |
|---|---|
| set | REACTOME_GABA_RECEPTOR_ACTIVATION |
| setSize | 57 |
| pANOVA | 0.0147 |
| s.dist | 0.187 |
| p.adjustANOVA | 0.636 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| GNGT2 | 10053 |
| GNAI2 | 9357 |
| GABRR2 | 9232 |
| KCNJ3 | 8793 |
| KCNJ5 | 7808 |
| GABRR1 | 7625 |
| KCNJ2 | 7604 |
| GABRB2 | 6633 |
| GNB1 | 6594 |
| GABRR3 | 6592 |
| ADCY5 | 6465 |
| GABRA4 | 6301 |
| GABRA1 | 6267 |
| GNAI1 | 6083 |
| KCNJ6 | 5885 |
| GABRB1 | 5617 |
| KCNJ10 | 5274 |
| GNG2 | 4394 |
| GABRG2 | 4362 |
| GNG13 | 4355 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| GNGT2 | 10053 |
| GNAI2 | 9357 |
| GABRR2 | 9232 |
| KCNJ3 | 8793 |
| KCNJ5 | 7808 |
| GABRR1 | 7625 |
| KCNJ2 | 7604 |
| GABRB2 | 6633 |
| GNB1 | 6594 |
| GABRR3 | 6592 |
| ADCY5 | 6465 |
| GABRA4 | 6301 |
| GABRA1 | 6267 |
| GNAI1 | 6083 |
| KCNJ6 | 5885 |
| GABRB1 | 5617 |
| KCNJ10 | 5274 |
| GNG2 | 4394 |
| GABRG2 | 4362 |
| GNG13 | 4355 |
| GNAT3 | 3829 |
| GABRG3 | 3751 |
| ADCY6 | 3433 |
| ADCY9 | 3186 |
| GNG11 | 2196 |
| ADCY8 | 1989 |
| NPTN | 1913 |
| ADCY4 | 1319 |
| ADCY7 | 992 |
| ADCY1 | 877 |
| GABBR2 | 677 |
| KCNJ9 | 590 |
| KCNJ4 | 510 |
| GABBR1 | 239 |
| GNAL | 162 |
| ADCY2 | -102 |
| GNGT1 | -114 |
| GNB3 | -122 |
| GNG5 | -594 |
| KCNJ16 | -755 |
| GNG12 | -1102 |
| GNG10 | -1690 |
| GABRA6 | -2142 |
| GNAI3 | -2862 |
| KCNJ15 | -2886 |
| GABRA2 | -3396 |
| ADCY3 | -3624 |
| GABRA5 | -4667 |
| GNG3 | -4759 |
| GNG4 | -5388 |
| KCNJ12 | -6121 |
| GABRB3 | -7030 |
| GNB4 | -7626 |
| GNB2 | -8837 |
| GNB5 | -8860 |
| GNG7 | -9020 |
| GNG8 | -9902 |
REACTOME_INFLAMMASOMES
| 1027 | |
|---|---|
| set | REACTOME_INFLAMMASOMES |
| setSize | 21 |
| pANOVA | 0.0155 |
| s.dist | -0.305 |
| p.adjustANOVA | 0.653 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| NLRC4 | -11069 |
| HMOX1 | -10727 |
| BCL2L1 | -10519 |
| CASP1 | -10218 |
| NLRP1 | -8896 |
| NFKB1 | -7717 |
| TXN | -7590 |
| TXNIP | -7024 |
| P2RX7 | -6546 |
| APP | -5711 |
| AIM2 | -5239 |
| MEFV | -3243 |
| SUGT1 | -3153 |
| RELA | -3097 |
| PYCARD | -2753 |
| NFKB2 | -568 |
| NLRP3 | 1626 |
| PSTPIP1 | 1841 |
| PANX1 | 3226 |
| BCL2 | 3392 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| NLRC4 | -11069 |
| HMOX1 | -10727 |
| BCL2L1 | -10519 |
| CASP1 | -10218 |
| NLRP1 | -8896 |
| NFKB1 | -7717 |
| TXN | -7590 |
| TXNIP | -7024 |
| P2RX7 | -6546 |
| APP | -5711 |
| AIM2 | -5239 |
| MEFV | -3243 |
| SUGT1 | -3153 |
| RELA | -3097 |
| PYCARD | -2753 |
| NFKB2 | -568 |
| NLRP3 | 1626 |
| PSTPIP1 | 1841 |
| PANX1 | 3226 |
| BCL2 | 3392 |
| HSP90AB1 | 6061 |
REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE
| 500 | |
|---|---|
| set | REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE |
| setSize | 228 |
| pANOVA | 0.0162 |
| s.dist | -0.0924 |
| p.adjustANOVA | 0.655 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TUBB8 | -11590 |
| PSMB11 | -11321 |
| TUBA4A | -10847 |
| SUMO1 | -10728 |
| UBE2E1 | -10694 |
| TUBB4A | -10582 |
| UBE2S | -10441 |
| FBXO5 | -10329 |
| NDEL1 | -10291 |
| PSMB9 | -10214 |
| PSMA5 | -10194 |
| DYNLL1 | -10134 |
| CHMP4A | -10068 |
| CHMP2A | -10054 |
| XPO1 | -9996 |
| SPC24 | -9916 |
| PSMB8 | -9839 |
| ZWINT | -9787 |
| PPP2R5D | -9565 |
| PPP2R2A | -9458 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TUBB8 | -11590 |
| PSMB11 | -11321 |
| TUBA4A | -10847 |
| SUMO1 | -10728 |
| UBE2E1 | -10694 |
| TUBB4A | -10582 |
| UBE2S | -10441 |
| FBXO5 | -10329 |
| NDEL1 | -10291 |
| PSMB9 | -10214 |
| PSMA5 | -10194 |
| DYNLL1 | -10134 |
| CHMP4A | -10068 |
| CHMP2A | -10054 |
| XPO1 | -9996 |
| SPC24 | -9916 |
| PSMB8 | -9839 |
| ZWINT | -9787 |
| PPP2R5D | -9565 |
| PPP2R2A | -9458 |
| TUBA4B | -9365 |
| VRK1 | -9319 |
| PPP2CA | -9312 |
| RCC1 | -9106 |
| RANBP2 | -8901 |
| SMC3 | -8792 |
| UBB | -8790 |
| CENPE | -8742 |
| TAOK1 | -8639 |
| ANAPC11 | -8493 |
| NUP98 | -8487 |
| PDS5B | -8458 |
| PSMB7 | -8319 |
| SKA1 | -8293 |
| PSME1 | -8170 |
| SKA2 | -7997 |
| PSMB6 | -7992 |
| CENPS | -7968 |
| ANAPC15 | -7796 |
| RANGAP1 | -7783 |
| CDC23 | -7642 |
| CKAP5 | -7460 |
| CDCA5 | -7409 |
| ANAPC1 | -7349 |
| ANKLE2 | -7330 |
| NUP37 | -7243 |
| PSMC4 | -7169 |
| AHCTF1 | -7162 |
| WAPL | -7151 |
| RAN | -6893 |
| RAD21 | -6890 |
| CENPA | -6739 |
| NUP155 | -6680 |
| PSME3 | -6558 |
| CENPH | -6486 |
| PAFAH1B1 | -6379 |
| VPS4A | -6339 |
| PSMD14 | -6115 |
| SEC13 | -6075 |
| NUP160 | -6038 |
| CENPK | -6032 |
| CHMP7 | -5975 |
| PSMA7 | -5868 |
| CDC26 | -5830 |
| PLK1 | -5723 |
| B9D2 | -5633 |
| POM121 | -5529 |
| CENPU | -5389 |
| KIF18A | -5303 |
| CHMP4B | -5294 |
| AURKB | -5178 |
| PSMD7 | -5158 |
| NUP107 | -5114 |
| LMNA | -4945 |
| LBR | -4939 |
| CENPT | -4928 |
| CHMP2B | -4834 |
| NUP205 | -4807 |
| PSMD8 | -4743 |
| KIF2B | -4720 |
| CENPN | -4706 |
| PPP1CC | -4676 |
| NDE1 | -4508 |
| KIF2A | -4442 |
| SPC25 | -4304 |
| ANAPC5 | -4281 |
| CDCA8 | -4251 |
| PSMD5 | -4189 |
| NUP188 | -4180 |
| TUBA1C | -4053 |
| VRK2 | -4048 |
| UBC | -3960 |
| PSMD11 | -3936 |
| TNPO1 | -3930 |
| DYNC1LI2 | -3917 |
| PSMB2 | -3889 |
| DYNC1I2 | -3835 |
| CENPL | -3802 |
| PPP2R5A | -3712 |
| CC2D1B | -3493 |
| NUP58 | -3490 |
| PSMA6 | -3468 |
| SGO1 | -3417 |
| PSMD9 | -3390 |
| RPS27A | -3374 |
| LMNB1 | -3362 |
| ZWILCH | -3264 |
| CCNB1 | -3233 |
| ANAPC7 | -3205 |
| KPNB1 | -3143 |
| UBE2C | -3089 |
| PSME4 | -3068 |
| PPP2R1A | -2973 |
| CLASP1 | -2708 |
| TUBA3D | -2604 |
| NSL1 | -2542 |
| PPP2CB | -2525 |
| PSMC5 | -2407 |
| BIRC5 | -2374 |
| NUP62 | -2238 |
| PSMA2 | -1982 |
| MAPRE1 | -1705 |
| SGO2 | -1683 |
| DYNC1I1 | -1599 |
| TMPO | -1559 |
| CENPC | -1208 |
| DYNC1H1 | -1161 |
| LEMD2 | -1114 |
| ESPL1 | -837 |
| LEMD3 | -810 |
| CENPP | -710 |
| PSMB1 | -649 |
| TUBB4B | -641 |
| PPP2R5E | -579 |
| KNTC1 | -428 |
| INCENP | -397 |
| PSMC1 | -332 |
| MIS12 | -297 |
| DYNC1LI1 | -283 |
| BUB1 | -279 |
| PSMD13 | -227 |
| PSMC6 | 25 |
| PSMD6 | 166 |
| TUBA1A | 318 |
| PSMF1 | 351 |
| PSMD2 | 438 |
| UBE2D1 | 455 |
| TUBB3 | 582 |
| NUP133 | 603 |
| PSMB10 | 869 |
| CENPQ | 1108 |
| PSMC2 | 1115 |
| PSMD1 | 1119 |
| CENPO | 1146 |
| CLASP2 | 1277 |
| PTTG1 | 1345 |
| ZW10 | 1362 |
| MAD1L1 | 1412 |
| SPAST | 1712 |
| STAG1 | 1716 |
| TUBA1B | 1730 |
| NDC1 | 1824 |
| PPP2R5C | 1880 |
| PSME2 | 1954 |
| ANAPC16 | 1988 |
| ITGB3BP | 2287 |
| PSMD12 | 2494 |
| ANAPC10 | 2561 |
| SPDL1 | 2746 |
| ANAPC4 | 2773 |
| CHMP6 | 2869 |
| PPP2R5B | 3021 |
| CDC16 | 3095 |
| NUP93 | 3123 |
| TUBB2A | 3132 |
| BUB3 | 3221 |
| CLIP1 | 3237 |
| SEH1L | 3261 |
| CDC20 | 3349 |
| MAD2L1 | 3532 |
| PSMA8 | 3597 |
| CHMP4C | 3664 |
| SEM1 | 3801 |
| RCC2 | 3852 |
| BUB1B | 3858 |
| TUBAL3 | 3868 |
| KNL1 | 3956 |
| ANAPC2 | 4109 |
| KIF2C | 4126 |
| PSMB4 | 4183 |
| CDC27 | 4326 |
| PSMD4 | 4365 |
| PDS5A | 4375 |
| CENPF | 4475 |
| IST1 | 4793 |
| BANF1 | 4852 |
| SIRT2 | 5031 |
| CDK1 | 5109 |
| TUBB1 | 5346 |
| CENPM | 5566 |
| PSMA4 | 5588 |
| PSMB5 | 5606 |
| NDC80 | 5633 |
| NUF2 | 5717 |
| CHMP3 | 5881 |
| DSN1 | 6194 |
| TUBA3C | 6217 |
| NUDC | 6266 |
| PSMB3 | 6513 |
| PSMA1 | 6519 |
| NUP54 | 6655 |
| PSMD3 | 6889 |
| PPP2R1B | 6984 |
| UBE2I | 7197 |
| PMF1 | 7266 |
| TUBB6 | 7617 |
| UBA52 | 7910 |
| PSMA3 | 7987 |
| TUBB2B | 8061 |
| PSMC3 | 8087 |
| RPS27 | 8110 |
| NUP43 | 8160 |
| NUP35 | 8282 |
| TUBA3E | 8431 |
| CCNB2 | 8638 |
| TUBA8 | 8640 |
| DYNLL2 | 8677 |
| NUP85 | 8816 |
REACTOME_CA2_ACTIVATED_K_CHANNELS
| 81 | |
|---|---|
| set | REACTOME_CA2_ACTIVATED_K_CHANNELS |
| setSize | 9 |
| pANOVA | 0.0167 |
| s.dist | 0.461 |
| p.adjustANOVA | 0.655 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| KCNMB1 | 9518 |
| KCNMA1 | 7468 |
| KCNN2 | 6462 |
| KCNN3 | 6106 |
| KCNN4 | 4685 |
| KCNMB3 | 4402 |
| KCNMB4 | 2072 |
| KCNN1 | 1886 |
| KCNMB2 | -4478 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| KCNMB1 | 9518 |
| KCNMA1 | 7468 |
| KCNN2 | 6462 |
| KCNN3 | 6106 |
| KCNN4 | 4685 |
| KCNMB3 | 4402 |
| KCNMB4 | 2072 |
| KCNN1 | 1886 |
| KCNMB2 | -4478 |
REACTOME_VESICLE_MEDIATED_TRANSPORT
| 934 | |
|---|---|
| set | REACTOME_VESICLE_MEDIATED_TRANSPORT |
| setSize | 642 |
| pANOVA | 0.0168 |
| s.dist | -0.0553 |
| p.adjustANOVA | 0.655 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| SCARF1 | -11620 |
| AREG | -11608 |
| TUBB8 | -11590 |
| AVP | -11350 |
| KDELR1 | -11305 |
| HP | -11299 |
| APOE | -11264 |
| RAB21 | -11099 |
| KIF3A | -11074 |
| HBA1 | -10986 |
| TUBA4A | -10847 |
| CAPZA2 | -10797 |
| SFN | -10778 |
| RABGAP1 | -10713 |
| MAN1C1 | -10614 |
| ARPC1A | -10590 |
| TUBB4A | -10582 |
| VPS36 | -10565 |
| TMED2 | -10492 |
| ALPP | -10490 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SCARF1 | -11620 |
| AREG | -11608 |
| TUBB8 | -11590 |
| AVP | -11350 |
| KDELR1 | -11305 |
| HP | -11299 |
| APOE | -11264 |
| RAB21 | -11099 |
| KIF3A | -11074 |
| HBA1 | -10986 |
| TUBA4A | -10847 |
| CAPZA2 | -10797 |
| SFN | -10778 |
| RABGAP1 | -10713 |
| MAN1C1 | -10614 |
| ARPC1A | -10590 |
| TUBB4A | -10582 |
| VPS36 | -10565 |
| TMED2 | -10492 |
| ALPP | -10490 |
| RGP1 | -10479 |
| VPS25 | -10460 |
| MON1A | -10454 |
| KIF21A | -10449 |
| GOLGA2 | -10423 |
| SCARB2 | -10404 |
| STON1 | -10358 |
| GOSR1 | -10334 |
| GALNT1 | -10181 |
| ACBD3 | -10143 |
| DYNLL1 | -10134 |
| CALR | -10123 |
| GJD4 | -10105 |
| FNBP1 | -10070 |
| CHMP4A | -10068 |
| COG7 | -10066 |
| CHMP2A | -10054 |
| KIF20B | -9982 |
| FOLR1 | -9963 |
| COPS8 | -9834 |
| RAB43 | -9794 |
| CNIH2 | -9779 |
| USP6NL | -9770 |
| GRK2 | -9768 |
| KLC1 | -9651 |
| RAB11B | -9528 |
| MARCO | -9503 |
| YWHAG | -9478 |
| RAB3GAP2 | -9461 |
| TRAPPC8 | -9455 |
| SYNJ1 | -9410 |
| SSC5D | -9407 |
| TUBA4B | -9365 |
| YKT6 | -9333 |
| SORT1 | -9223 |
| FTH1 | -8939 |
| COLEC11 | -8936 |
| APOA1 | -8926 |
| COG2 | -8908 |
| TGOLN2 | -8867 |
| CAPZA3 | -8856 |
| BLOC1S3 | -8822 |
| EPS15 | -8816 |
| STAM | -8791 |
| UBB | -8790 |
| RAB7A | -8782 |
| STX10 | -8778 |
| CENPE | -8742 |
| CPD | -8717 |
| ANKRD27 | -8699 |
| VTA1 | -8670 |
| RAB3A | -8649 |
| TRAPPC6A | -8621 |
| CYTH3 | -8597 |
| LMAN1L | -8536 |
| RAC1 | -8501 |
| FCHO1 | -8435 |
| VPS54 | -8403 |
| VPS37A | -8376 |
| RAB11A | -8333 |
| NAPA | -8332 |
| DENND5A | -8280 |
| RAB30 | -8169 |
| TBC1D13 | -8158 |
| COPG1 | -8078 |
| CLINT1 | -8059 |
| EPGN | -8050 |
| KIF4B | -8005 |
| MVB12A | -7986 |
| KIFC2 | -7983 |
| GJA5 | -7951 |
| HPR | -7949 |
| SYT9 | -7908 |
| NECAP2 | -7867 |
| AP1M2 | -7850 |
| TMED9 | -7847 |
| YWHAQ | -7813 |
| KLC3 | -7788 |
| AP4E1 | -7760 |
| DCTN2 | -7699 |
| REPS1 | -7694 |
| COPS3 | -7685 |
| BLOC1S1 | -7612 |
| CYTH4 | -7608 |
| PICALM | -7427 |
| GJC1 | -7421 |
| COPB2 | -7408 |
| RAB12 | -7401 |
| TFG | -7358 |
| DENND1B | -7346 |
| COPZ1 | -7291 |
| RHOBTB3 | -7283 |
| DNM3 | -7245 |
| COPS5 | -7224 |
| KIF1C | -7199 |
| GRK3 | -7179 |
| CLTCL1 | -7130 |
| ACTR1A | -7122 |
| WASL | -7100 |
| PRKAG1 | -7069 |
| CHRM2 | -7066 |
| PPP6R3 | -7061 |
| ARPC4 | -7049 |
| SEC22A | -7017 |
| MCFD2 | -6982 |
| SLC2A8 | -6930 |
| RACGAP1 | -6926 |
| ANKRD28 | -6909 |
| BIN1 | -6835 |
| M6PR | -6780 |
| TBC1D7 | -6769 |
| C2CD5 | -6756 |
| AP4M1 | -6735 |
| TOR1B | -6728 |
| YWHAZ | -6700 |
| TACR1 | -6605 |
| KDELR2 | -6588 |
| EXOC4 | -6549 |
| STAM2 | -6544 |
| ANK3 | -6519 |
| PACSIN1 | -6516 |
| PACSIN2 | -6515 |
| CTSZ | -6514 |
| KIF22 | -6478 |
| SEC23IP | -6448 |
| VPS51 | -6443 |
| COPS2 | -6398 |
| FTL | -6388 |
| PAFAH1B1 | -6379 |
| STXBP3 | -6344 |
| VPS4A | -6339 |
| AMBP | -6320 |
| SYT8 | -6248 |
| AP1S1 | -6234 |
| CUX1 | -6207 |
| SH3GL3 | -6203 |
| SH3D19 | -6185 |
| PPP6R1 | -6109 |
| SEC13 | -6075 |
| CHMP7 | -5975 |
| NBAS | -5970 |
| HYOU1 | -5812 |
| KIF5B | -5765 |
| MIA2 | -5738 |
| ANK2 | -5716 |
| APP | -5711 |
| TBC1D20 | -5622 |
| PAFAH1B3 | -5582 |
| MAN1A1 | -5580 |
| RAB4A | -5571 |
| VAMP2 | -5566 |
| LNPEP | -5563 |
| AP1G1 | -5545 |
| AP1G2 | -5485 |
| CD4 | -5453 |
| USE1 | -5425 |
| COG5 | -5420 |
| TRIP11 | -5350 |
| GOLGA1 | -5349 |
| DNASE2 | -5347 |
| SPTBN4 | -5317 |
| KIF18A | -5303 |
| CHMP4B | -5294 |
| KIF1B | -5287 |
| AP4B1 | -5280 |
| CD163 | -5254 |
| SPTAN1 | -5203 |
| SNAP29 | -5190 |
| TRAPPC3 | -5188 |
| CYTH1 | -5185 |
| ARFGAP3 | -5173 |
| KIAA0319 | -5110 |
| GJA1 | -5092 |
| STX17 | -5083 |
| RAB6A | -5055 |
| GORASP1 | -5038 |
| VPS4B | -4954 |
| ARL1 | -4891 |
| SCFD1 | -4886 |
| RAB13 | -4866 |
| CHMP2B | -4834 |
| NAPB | -4820 |
| EXOC6 | -4815 |
| HGS | -4795 |
| SNAPIN | -4739 |
| KIF2B | -4720 |
| RIC1 | -4708 |
| COPB1 | -4689 |
| AGTR1 | -4681 |
| LMAN2L | -4599 |
| GJA9 | -4577 |
| VPS52 | -4552 |
| SYTL1 | -4546 |
| PLIN3 | -4542 |
| KIF6 | -4538 |
| YWHAE | -4537 |
| ARFRP1 | -4506 |
| SEC16B | -4492 |
| KIF2A | -4442 |
| SNX9 | -4438 |
| F5 | -4425 |
| CBL | -4421 |
| AP4S1 | -4407 |
| RAB1B | -4395 |
| CNIH1 | -4379 |
| KIF9 | -4377 |
| GJC2 | -4325 |
| ASPSCR1 | -4287 |
| EXOC2 | -4213 |
| KIF13B | -4204 |
| AP1M1 | -4178 |
| TMEM115 | -4158 |
| GPS1 | -4125 |
| DCTN4 | -4079 |
| TUBA1C | -4053 |
| SRC | -4047 |
| SBF2 | -4025 |
| OPTN | -4008 |
| RAB18 | -3976 |
| UBC | -3960 |
| RAB31 | -3923 |
| DYNC1LI2 | -3917 |
| PIK3C2A | -3906 |
| DYNC1I2 | -3835 |
| SEC24B | -3817 |
| VPS37B | -3767 |
| DENND6A | -3662 |
| KIF21B | -3603 |
| KLC2 | -3596 |
| GALNT2 | -3552 |
| RAB3IL1 | -3515 |
| DCTN6 | -3463 |
| KIF23 | -3459 |
| BLOC1S4 | -3445 |
| ARF3 | -3409 |
| MSR1 | -3401 |
| VPS37C | -3384 |
| RPS27A | -3374 |
| TBC1D16 | -3323 |
| SNAP23 | -3277 |
| GBF1 | -3251 |
| GGA2 | -3227 |
| EXOC3 | -3177 |
| CSNK1D | -3170 |
| MIA3 | -3155 |
| DNAJC6 | -3147 |
| HPX | -3111 |
| UBAP1 | -3098 |
| DCTN5 | -3071 |
| HSP90B1 | -3056 |
| RAB5A | -3055 |
| SEC31A | -3054 |
| AGFG1 | -3040 |
| ARFGAP2 | -2988 |
| MAN2A1 | -2893 |
| KIF1A | -2824 |
| PIP5K1C | -2775 |
| HPS1 | -2768 |
| CLTB | -2762 |
| DENND1C | -2730 |
| GAPVD1 | -2725 |
| GJD3 | -2705 |
| COG1 | -2650 |
| RABEPK | -2641 |
| STX6 | -2638 |
| DENND1A | -2623 |
| TUBA3D | -2604 |
| CAPZA1 | -2585 |
| COL3A1 | -2564 |
| KLC4 | -2552 |
| KIFC1 | -2508 |
| SEC22C | -2499 |
| KDELR3 | -2396 |
| GRIA1 | -2393 |
| GOLGA5 | -2365 |
| RAB36 | -2362 |
| ACTG1 | -2359 |
| AP3S1 | -2330 |
| AAK1 | -2317 |
| SH3GL1 | -2255 |
| COG4 | -2248 |
| EPN2 | -2184 |
| LMAN1 | -2167 |
| NSF | -2159 |
| KIF25 | -2119 |
| SNX2 | -2031 |
| PLA2G6 | -2009 |
| TRAPPC11 | -1989 |
| ARFIP2 | -1970 |
| NECAP1 | -1964 |
| TPD52 | -1939 |
| TMF1 | -1909 |
| MON1B | -1847 |
| COPS6 | -1833 |
| SERPINA1 | -1802 |
| AP2A2 | -1773 |
| HIP1R | -1769 |
| SEC23A | -1691 |
| RINT1 | -1677 |
| CD59 | -1661 |
| DENND5B | -1618 |
| ARPC3 | -1613 |
| DYNC1I1 | -1599 |
| ARF1 | -1577 |
| TSC2 | -1459 |
| RAB39A | -1434 |
| HBEGF | -1424 |
| TFRC | -1416 |
| MASP1 | -1407 |
| DENND2B | -1391 |
| RIN1 | -1381 |
| TBC1D24 | -1336 |
| SURF4 | -1326 |
| IGF2R | -1310 |
| ARFGAP1 | -1266 |
| KIF16B | -1202 |
| DYNC1H1 | -1161 |
| HIP1 | -1137 |
| CLTC | -1126 |
| GJB2 | -1122 |
| DVL2 | -1119 |
| ANK1 | -1061 |
| APOL1 | -1035 |
| AP1B1 | -1032 |
| CAPZB | -1025 |
| GOLGA4 | -970 |
| DTNBP1 | -956 |
| DNM1 | -940 |
| VPS37D | -931 |
| TBC1D17 | -904 |
| GCC2 | -876 |
| HBB | -860 |
| BICD1 | -850 |
| DENND4C | -817 |
| STX5 | -802 |
| RALA | -794 |
| STAB2 | -766 |
| COPS7A | -756 |
| COL1A2 | -735 |
| TJP1 | -729 |
| NAA35 | -728 |
| SEC24A | -669 |
| TBC1D2 | -645 |
| TUBB4B | -641 |
| GCC1 | -626 |
| ARPC2 | -618 |
| TMED10 | -585 |
| COG8 | -528 |
| VPS53 | -527 |
| TGFA | -493 |
| SEC22B | -481 |
| LDLRAP1 | -466 |
| DENND4A | -456 |
| SNX5 | -453 |
| TPD52L1 | -344 |
| DYNC1LI1 | -283 |
| EPS15L1 | -275 |
| DENND2A | -271 |
| SYNJ2 | -251 |
| VTI1A | -232 |
| TRAPPC2L | -105 |
| STX16 | -33 |
| ULK1 | -26 |
| SPTBN2 | -2 |
| TBC1D1 | 173 |
| KIF15 | 192 |
| BTC | 200 |
| GOSR2 | 228 |
| GABARAPL2 | 266 |
| MADD | 288 |
| VPS28 | 303 |
| TUBA1A | 318 |
| YWHAB | 342 |
| GOLGB1 | 347 |
| SLC18A3 | 483 |
| RIN2 | 492 |
| HSP90AA1 | 498 |
| AP2S1 | 531 |
| SCOC | 533 |
| TF | 580 |
| TUBB3 | 582 |
| DENND4B | 587 |
| LDLR | 643 |
| COL4A2 | 749 |
| ADRB2 | 768 |
| STON2 | 825 |
| LMAN2 | 831 |
| MYO6 | 857 |
| FCHO2 | 873 |
| GNS | 893 |
| STAB1 | 909 |
| SNF8 | 927 |
| TBC1D14 | 947 |
| PRKAG2 | 962 |
| GJB4 | 968 |
| ACTR10 | 974 |
| TBC1D10B | 1040 |
| CLVS1 | 1049 |
| TRAPPC9 | 1075 |
| NEDD8 | 1171 |
| AP2B1 | 1177 |
| CYTH2 | 1184 |
| COL1A1 | 1201 |
| EXOC5 | 1251 |
| RAB3GAP1 | 1266 |
| SPTBN1 | 1334 |
| RABEP1 | 1351 |
| ZW10 | 1362 |
| PACSIN3 | 1467 |
| YWHAH | 1509 |
| AKT2 | 1521 |
| EXOC1 | 1568 |
| TBC1D15 | 1670 |
| GAK | 1686 |
| TUBA1B | 1730 |
| GJB5 | 1745 |
| TRIP10 | 1746 |
| ARF6 | 1750 |
| KIF19 | 1763 |
| RALGAPB | 1774 |
| KIF3B | 1813 |
| RAB1A | 1846 |
| TRAPPC10 | 1857 |
| TXNDC5 | 1866 |
| MYO1C | 1935 |
| ARF4 | 1970 |
| GDI2 | 2006 |
| STX18 | 2110 |
| VPS45 | 2205 |
| GJA3 | 2225 |
| SCARB1 | 2244 |
| PUM1 | 2246 |
| RALGAPA2 | 2257 |
| BET1L | 2274 |
| GJB3 | 2308 |
| RAB8B | 2313 |
| KIF18B | 2318 |
| KIF27 | 2407 |
| LRP1 | 2411 |
| TRAPPC6B | 2427 |
| AP2M1 | 2466 |
| ITSN2 | 2487 |
| AP2A1 | 2500 |
| SYT11 | 2554 |
| GJD2 | 2567 |
| COPZ2 | 2581 |
| ACTR2 | 2584 |
| TRAPPC12 | 2618 |
| TRAPPC1 | 2657 |
| ARRB1 | 2670 |
| VAMP8 | 2687 |
| PRKAB2 | 2720 |
| TSC1 | 2738 |
| CLTA | 2780 |
| SAR1B | 2783 |
| KIF26A | 2813 |
| RAB5C | 2816 |
| FZD4 | 2821 |
| ARCN1 | 2823 |
| SH3GL2 | 2868 |
| CHMP6 | 2869 |
| TSG101 | 2886 |
| TRAPPC4 | 2887 |
| KIF26B | 2924 |
| NAA30 | 2931 |
| COPG2 | 2943 |
| ARRB2 | 3002 |
| GGA3 | 3012 |
| RAB10 | 3030 |
| TUBB2A | 3132 |
| MAN1A2 | 3134 |
| GABARAP | 3191 |
| KIF20A | 3416 |
| BET1 | 3427 |
| ALB | 3438 |
| KIF3C | 3485 |
| SLC2A4 | 3489 |
| ARPC5 | 3563 |
| GJB7 | 3606 |
| HSPH1 | 3622 |
| TMED3 | 3623 |
| CHMP4C | 3664 |
| KIFAP3 | 3729 |
| SEC24D | 3822 |
| COPE | 3857 |
| TUBAL3 | 3868 |
| COG3 | 3916 |
| COL4A1 | 3933 |
| HPS4 | 3993 |
| EPN1 | 3995 |
| RAB14 | 4054 |
| RAB5B | 4118 |
| COPS4 | 4123 |
| KIF2C | 4126 |
| SYT2 | 4153 |
| GGA1 | 4179 |
| HSPA8 | 4201 |
| AP3B1 | 4209 |
| SEC16A | 4216 |
| TRAPPC13 | 4264 |
| MAP1LC3B | 4309 |
| GJA10 | 4313 |
| GJA8 | 4354 |
| KIF11 | 4363 |
| ITSN1 | 4396 |
| EGFR | 4403 |
| CALM1 | 4408 |
| AGPAT3 | 4416 |
| AKT3 | 4420 |
| EXOC8 | 4495 |
| UBQLN1 | 4549 |
| BLOC1S6 | 4644 |
| ACTR3 | 4677 |
| RAB6B | 4733 |
| RAB38 | 4735 |
| COPA | 4736 |
| RABGEF1 | 4747 |
| EREG | 4801 |
| COLEC12 | 4804 |
| VAMP4 | 4827 |
| TBC1D4 | 4831 |
| MAN2A2 | 4938 |
| MVB12B | 5003 |
| COG6 | 5046 |
| EGF | 5066 |
| CD36 | 5163 |
| NAA38 | 5236 |
| VAMP3 | 5261 |
| DNM2 | 5273 |
| TBC1D10A | 5326 |
| TUBB1 | 5346 |
| RAB3IP | 5348 |
| LRP2 | 5409 |
| NAPG | 5432 |
| SNAP91 | 5441 |
| SEC24C | 5488 |
| RAB27B | 5590 |
| SCARA5 | 5621 |
| PRKAB1 | 5642 |
| RAB27A | 5652 |
| DENND3 | 5653 |
| STX4 | 5678 |
| CHMP5 | 5701 |
| COPS7B | 5746 |
| GRB2 | 5787 |
| MYH9 | 5790 |
| GOLIM4 | 5821 |
| USO1 | 5838 |
| AMPH | 5858 |
| CHMP3 | 5881 |
| GJB6 | 5886 |
| MYO5A | 5901 |
| SYT1 | 6001 |
| ACTB | 6012 |
| BICD2 | 6082 |
| PAFAH1B2 | 6094 |
| RIN3 | 6109 |
| DENND6B | 6112 |
| SBF1 | 6198 |
| TUBA3C | 6217 |
| DCTN1 | 6219 |
| PRKAA2 | 6287 |
| RAB33B | 6369 |
| EXOC7 | 6376 |
| SGIP1 | 6415 |
| PLA2G4A | 6436 |
| CTTN | 6440 |
| RAB32 | 6447 |
| COL7A1 | 6457 |
| TRAPPC5 | 6630 |
| DCTN3 | 6735 |
| ALS2 | 6763 |
| AP1S3 | 6802 |
| SNX18 | 6854 |
| RAB8A | 7033 |
| CD55 | 7097 |
| WNT5A | 7123 |
| CTSC | 7289 |
| KIF5A | 7357 |
| PPP6C | 7462 |
| SPTA1 | 7519 |
| AKT1 | 7547 |
| TMED7 | 7548 |
| HBA2 | 7611 |
| TUBB6 | 7617 |
| CLVS2 | 7743 |
| ALS2CL | 7764 |
| RHOQ | 7811 |
| SPTB | 7879 |
| UBA52 | 7910 |
| APOB | 7935 |
| FNBP1L | 7988 |
| RAB35 | 7994 |
| TUBB2B | 8061 |
| DENND2C | 8216 |
| TOR1A | 8291 |
| SPTBN5 | 8293 |
| INS | 8351 |
| SYS1 | 8396 |
| TUBA3E | 8431 |
| RINL | 8437 |
| BNIP1 | 8529 |
| SCGB3A2 | 8576 |
| PRKAG3 | 8602 |
| TUBA8 | 8640 |
| DYNLL2 | 8677 |
| CFTR | 8755 |
| CNIH3 | 8778 |
| JCHAIN | 8828 |
| DAB2 | 8933 |
| TBC1D10C | 8945 |
| PREB | 9078 |
| ARF5 | 9302 |
| DENND2D | 9323 |
| CD3G | 9577 |
| KIF12 | 9615 |
| CHML | 9731 |
| SPARC | 9913 |
| GJA4 | 9928 |
| CD3D | 9965 |
| IL7R | 9967 |
| SAA1 | 10054 |
REACTOME_ACETYLCHOLINE_INHIBITS_CONTRACTION_OF_OUTER_HAIR_CELLS
| 1526 | |
|---|---|
| set | REACTOME_ACETYLCHOLINE_INHIBITS_CONTRACTION_OF_OUTER_HAIR_CELLS |
| setSize | 5 |
| pANOVA | 0.0176 |
| s.dist | 0.613 |
| p.adjustANOVA | 0.673 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| KCNMB1 | 9518 |
| CHRNA10 | 7876 |
| KCNMA1 | 7468 |
| KCNN2 | 6462 |
| CHRNA9 | -1776 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| KCNMB1 | 9518 |
| CHRNA10 | 7876 |
| KCNMA1 | 7468 |
| KCNN2 | 6462 |
| CHRNA9 | -1776 |
REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES
| 394 | |
|---|---|
| set | REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES |
| setSize | 30 |
| pANOVA | 0.0183 |
| s.dist | 0.249 |
| p.adjustANOVA | 0.682 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CD3D | 9965 |
| CD3E | 9583 |
| CD3G | 9577 |
| ZAP70 | 9507 |
| HLA-DRA | 9049 |
| HLA-DQB2 | 8376 |
| CD247 | 8350 |
| EVL | 6861 |
| LAT | 5591 |
| LCK | 4485 |
| PLCG2 | 3274 |
| PLCG1 | 2718 |
| GRAP2 | 2559 |
| HLA-DPB1 | 2051 |
| ENAH | 1553 |
| NCK1 | 1474 |
| ITK | 1071 |
| HLA-DPA1 | 995 |
| HLA-DQB1 | 884 |
| VASP | 751 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CD3D | 9965 |
| CD3E | 9583 |
| CD3G | 9577 |
| ZAP70 | 9507 |
| HLA-DRA | 9049 |
| HLA-DQB2 | 8376 |
| CD247 | 8350 |
| EVL | 6861 |
| LAT | 5591 |
| LCK | 4485 |
| PLCG2 | 3274 |
| PLCG1 | 2718 |
| GRAP2 | 2559 |
| HLA-DPB1 | 2051 |
| ENAH | 1553 |
| NCK1 | 1474 |
| ITK | 1071 |
| HLA-DPA1 | 995 |
| HLA-DQB1 | 884 |
| VASP | 751 |
| HLA-DRB5 | -543 |
| HLA-DQA1 | -1417 |
| HLA-DRB1 | -1914 |
| PAK2 | -2914 |
| FYB1 | -2936 |
| CD101 | -5234 |
| CD4 | -5453 |
| PAK1 | -5494 |
| HLA-DQA2 | -5579 |
| LCP2 | -10127 |
REACTOME_GERM_LAYER_FORMATION_AT_GASTRULATION
| 1599 | |
|---|---|
| set | REACTOME_GERM_LAYER_FORMATION_AT_GASTRULATION |
| setSize | 17 |
| pANOVA | 0.0198 |
| s.dist | 0.327 |
| p.adjustANOVA | 0.718 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TCF7 | 9914 |
| MIXL1 | 9155 |
| SMAD3 | 7259 |
| SOX2 | 7172 |
| FOXH1 | 7039 |
| TBXT | 6453 |
| GSC | 3554 |
| TBPL2 | 3373 |
| NANOG | 2721 |
| BMP4 | 1073 |
| LEF1 | 998 |
| SMAD4 | -254 |
| SMAD2 | -263 |
| POU5F1 | -730 |
| CTNNB1 | -1056 |
| EOMES | -2833 |
| TRIM33 | -6707 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TCF7 | 9914 |
| MIXL1 | 9155 |
| SMAD3 | 7259 |
| SOX2 | 7172 |
| FOXH1 | 7039 |
| TBXT | 6453 |
| GSC | 3554 |
| TBPL2 | 3373 |
| NANOG | 2721 |
| BMP4 | 1073 |
| LEF1 | 998 |
| SMAD4 | -254 |
| SMAD2 | -263 |
| POU5F1 | -730 |
| CTNNB1 | -1056 |
| EOMES | -2833 |
| TRIM33 | -6707 |
REACTOME_MEMBRANE_TRAFFICKING
| 374 | |
|---|---|
| set | REACTOME_MEMBRANE_TRAFFICKING |
| setSize | 603 |
| pANOVA | 0.0203 |
| s.dist | -0.0553 |
| p.adjustANOVA | 0.718 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| AREG | -11608 |
| TUBB8 | -11590 |
| AVP | -11350 |
| KDELR1 | -11305 |
| RAB21 | -11099 |
| KIF3A | -11074 |
| TUBA4A | -10847 |
| CAPZA2 | -10797 |
| SFN | -10778 |
| RABGAP1 | -10713 |
| MAN1C1 | -10614 |
| ARPC1A | -10590 |
| TUBB4A | -10582 |
| VPS36 | -10565 |
| TMED2 | -10492 |
| ALPP | -10490 |
| RGP1 | -10479 |
| VPS25 | -10460 |
| MON1A | -10454 |
| KIF21A | -10449 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| AREG | -11608 |
| TUBB8 | -11590 |
| AVP | -11350 |
| KDELR1 | -11305 |
| RAB21 | -11099 |
| KIF3A | -11074 |
| TUBA4A | -10847 |
| CAPZA2 | -10797 |
| SFN | -10778 |
| RABGAP1 | -10713 |
| MAN1C1 | -10614 |
| ARPC1A | -10590 |
| TUBB4A | -10582 |
| VPS36 | -10565 |
| TMED2 | -10492 |
| ALPP | -10490 |
| RGP1 | -10479 |
| VPS25 | -10460 |
| MON1A | -10454 |
| KIF21A | -10449 |
| GOLGA2 | -10423 |
| SCARB2 | -10404 |
| STON1 | -10358 |
| GOSR1 | -10334 |
| GALNT1 | -10181 |
| ACBD3 | -10143 |
| DYNLL1 | -10134 |
| GJD4 | -10105 |
| FNBP1 | -10070 |
| CHMP4A | -10068 |
| COG7 | -10066 |
| CHMP2A | -10054 |
| KIF20B | -9982 |
| FOLR1 | -9963 |
| COPS8 | -9834 |
| RAB43 | -9794 |
| CNIH2 | -9779 |
| USP6NL | -9770 |
| GRK2 | -9768 |
| KLC1 | -9651 |
| RAB11B | -9528 |
| YWHAG | -9478 |
| RAB3GAP2 | -9461 |
| TRAPPC8 | -9455 |
| SYNJ1 | -9410 |
| TUBA4B | -9365 |
| YKT6 | -9333 |
| SORT1 | -9223 |
| FTH1 | -8939 |
| COG2 | -8908 |
| TGOLN2 | -8867 |
| CAPZA3 | -8856 |
| BLOC1S3 | -8822 |
| EPS15 | -8816 |
| STAM | -8791 |
| UBB | -8790 |
| RAB7A | -8782 |
| STX10 | -8778 |
| CENPE | -8742 |
| CPD | -8717 |
| ANKRD27 | -8699 |
| VTA1 | -8670 |
| RAB3A | -8649 |
| TRAPPC6A | -8621 |
| CYTH3 | -8597 |
| LMAN1L | -8536 |
| RAC1 | -8501 |
| FCHO1 | -8435 |
| VPS54 | -8403 |
| VPS37A | -8376 |
| RAB11A | -8333 |
| NAPA | -8332 |
| DENND5A | -8280 |
| RAB30 | -8169 |
| TBC1D13 | -8158 |
| COPG1 | -8078 |
| CLINT1 | -8059 |
| EPGN | -8050 |
| KIF4B | -8005 |
| MVB12A | -7986 |
| KIFC2 | -7983 |
| GJA5 | -7951 |
| SYT9 | -7908 |
| NECAP2 | -7867 |
| AP1M2 | -7850 |
| TMED9 | -7847 |
| YWHAQ | -7813 |
| KLC3 | -7788 |
| AP4E1 | -7760 |
| DCTN2 | -7699 |
| REPS1 | -7694 |
| COPS3 | -7685 |
| BLOC1S1 | -7612 |
| CYTH4 | -7608 |
| PICALM | -7427 |
| GJC1 | -7421 |
| COPB2 | -7408 |
| RAB12 | -7401 |
| TFG | -7358 |
| DENND1B | -7346 |
| COPZ1 | -7291 |
| RHOBTB3 | -7283 |
| DNM3 | -7245 |
| COPS5 | -7224 |
| KIF1C | -7199 |
| GRK3 | -7179 |
| CLTCL1 | -7130 |
| ACTR1A | -7122 |
| WASL | -7100 |
| PRKAG1 | -7069 |
| CHRM2 | -7066 |
| PPP6R3 | -7061 |
| ARPC4 | -7049 |
| SEC22A | -7017 |
| MCFD2 | -6982 |
| SLC2A8 | -6930 |
| RACGAP1 | -6926 |
| ANKRD28 | -6909 |
| BIN1 | -6835 |
| M6PR | -6780 |
| TBC1D7 | -6769 |
| C2CD5 | -6756 |
| AP4M1 | -6735 |
| TOR1B | -6728 |
| YWHAZ | -6700 |
| TACR1 | -6605 |
| KDELR2 | -6588 |
| EXOC4 | -6549 |
| STAM2 | -6544 |
| ANK3 | -6519 |
| PACSIN1 | -6516 |
| PACSIN2 | -6515 |
| CTSZ | -6514 |
| KIF22 | -6478 |
| SEC23IP | -6448 |
| VPS51 | -6443 |
| COPS2 | -6398 |
| FTL | -6388 |
| PAFAH1B1 | -6379 |
| STXBP3 | -6344 |
| VPS4A | -6339 |
| SYT8 | -6248 |
| AP1S1 | -6234 |
| CUX1 | -6207 |
| SH3GL3 | -6203 |
| SH3D19 | -6185 |
| PPP6R1 | -6109 |
| SEC13 | -6075 |
| CHMP7 | -5975 |
| NBAS | -5970 |
| KIF5B | -5765 |
| MIA2 | -5738 |
| ANK2 | -5716 |
| APP | -5711 |
| TBC1D20 | -5622 |
| PAFAH1B3 | -5582 |
| MAN1A1 | -5580 |
| RAB4A | -5571 |
| VAMP2 | -5566 |
| LNPEP | -5563 |
| AP1G1 | -5545 |
| AP1G2 | -5485 |
| CD4 | -5453 |
| USE1 | -5425 |
| COG5 | -5420 |
| TRIP11 | -5350 |
| GOLGA1 | -5349 |
| DNASE2 | -5347 |
| SPTBN4 | -5317 |
| KIF18A | -5303 |
| CHMP4B | -5294 |
| KIF1B | -5287 |
| AP4B1 | -5280 |
| SPTAN1 | -5203 |
| SNAP29 | -5190 |
| TRAPPC3 | -5188 |
| CYTH1 | -5185 |
| ARFGAP3 | -5173 |
| KIAA0319 | -5110 |
| GJA1 | -5092 |
| STX17 | -5083 |
| RAB6A | -5055 |
| GORASP1 | -5038 |
| VPS4B | -4954 |
| ARL1 | -4891 |
| SCFD1 | -4886 |
| RAB13 | -4866 |
| CHMP2B | -4834 |
| NAPB | -4820 |
| EXOC6 | -4815 |
| HGS | -4795 |
| SNAPIN | -4739 |
| KIF2B | -4720 |
| RIC1 | -4708 |
| COPB1 | -4689 |
| AGTR1 | -4681 |
| LMAN2L | -4599 |
| GJA9 | -4577 |
| VPS52 | -4552 |
| SYTL1 | -4546 |
| PLIN3 | -4542 |
| KIF6 | -4538 |
| YWHAE | -4537 |
| ARFRP1 | -4506 |
| SEC16B | -4492 |
| KIF2A | -4442 |
| SNX9 | -4438 |
| F5 | -4425 |
| CBL | -4421 |
| AP4S1 | -4407 |
| RAB1B | -4395 |
| CNIH1 | -4379 |
| KIF9 | -4377 |
| GJC2 | -4325 |
| ASPSCR1 | -4287 |
| EXOC2 | -4213 |
| KIF13B | -4204 |
| AP1M1 | -4178 |
| TMEM115 | -4158 |
| GPS1 | -4125 |
| DCTN4 | -4079 |
| TUBA1C | -4053 |
| SRC | -4047 |
| SBF2 | -4025 |
| OPTN | -4008 |
| RAB18 | -3976 |
| UBC | -3960 |
| RAB31 | -3923 |
| DYNC1LI2 | -3917 |
| PIK3C2A | -3906 |
| DYNC1I2 | -3835 |
| SEC24B | -3817 |
| VPS37B | -3767 |
| DENND6A | -3662 |
| KIF21B | -3603 |
| KLC2 | -3596 |
| GALNT2 | -3552 |
| RAB3IL1 | -3515 |
| DCTN6 | -3463 |
| KIF23 | -3459 |
| BLOC1S4 | -3445 |
| ARF3 | -3409 |
| VPS37C | -3384 |
| RPS27A | -3374 |
| TBC1D16 | -3323 |
| SNAP23 | -3277 |
| GBF1 | -3251 |
| GGA2 | -3227 |
| EXOC3 | -3177 |
| CSNK1D | -3170 |
| MIA3 | -3155 |
| DNAJC6 | -3147 |
| UBAP1 | -3098 |
| DCTN5 | -3071 |
| RAB5A | -3055 |
| SEC31A | -3054 |
| AGFG1 | -3040 |
| ARFGAP2 | -2988 |
| MAN2A1 | -2893 |
| KIF1A | -2824 |
| PIP5K1C | -2775 |
| HPS1 | -2768 |
| CLTB | -2762 |
| DENND1C | -2730 |
| GAPVD1 | -2725 |
| GJD3 | -2705 |
| COG1 | -2650 |
| RABEPK | -2641 |
| STX6 | -2638 |
| DENND1A | -2623 |
| TUBA3D | -2604 |
| CAPZA1 | -2585 |
| KLC4 | -2552 |
| KIFC1 | -2508 |
| SEC22C | -2499 |
| KDELR3 | -2396 |
| GRIA1 | -2393 |
| GOLGA5 | -2365 |
| RAB36 | -2362 |
| ACTG1 | -2359 |
| AP3S1 | -2330 |
| AAK1 | -2317 |
| SH3GL1 | -2255 |
| COG4 | -2248 |
| EPN2 | -2184 |
| LMAN1 | -2167 |
| NSF | -2159 |
| KIF25 | -2119 |
| SNX2 | -2031 |
| PLA2G6 | -2009 |
| TRAPPC11 | -1989 |
| ARFIP2 | -1970 |
| NECAP1 | -1964 |
| TPD52 | -1939 |
| TMF1 | -1909 |
| MON1B | -1847 |
| COPS6 | -1833 |
| SERPINA1 | -1802 |
| AP2A2 | -1773 |
| HIP1R | -1769 |
| SEC23A | -1691 |
| RINT1 | -1677 |
| CD59 | -1661 |
| DENND5B | -1618 |
| ARPC3 | -1613 |
| DYNC1I1 | -1599 |
| ARF1 | -1577 |
| TSC2 | -1459 |
| RAB39A | -1434 |
| HBEGF | -1424 |
| TFRC | -1416 |
| DENND2B | -1391 |
| RIN1 | -1381 |
| TBC1D24 | -1336 |
| SURF4 | -1326 |
| IGF2R | -1310 |
| ARFGAP1 | -1266 |
| KIF16B | -1202 |
| DYNC1H1 | -1161 |
| HIP1 | -1137 |
| CLTC | -1126 |
| GJB2 | -1122 |
| DVL2 | -1119 |
| ANK1 | -1061 |
| AP1B1 | -1032 |
| CAPZB | -1025 |
| GOLGA4 | -970 |
| DTNBP1 | -956 |
| DNM1 | -940 |
| VPS37D | -931 |
| TBC1D17 | -904 |
| GCC2 | -876 |
| BICD1 | -850 |
| DENND4C | -817 |
| STX5 | -802 |
| RALA | -794 |
| COPS7A | -756 |
| TJP1 | -729 |
| NAA35 | -728 |
| SEC24A | -669 |
| TBC1D2 | -645 |
| TUBB4B | -641 |
| GCC1 | -626 |
| ARPC2 | -618 |
| TMED10 | -585 |
| COG8 | -528 |
| VPS53 | -527 |
| TGFA | -493 |
| SEC22B | -481 |
| LDLRAP1 | -466 |
| DENND4A | -456 |
| SNX5 | -453 |
| TPD52L1 | -344 |
| DYNC1LI1 | -283 |
| EPS15L1 | -275 |
| DENND2A | -271 |
| SYNJ2 | -251 |
| VTI1A | -232 |
| TRAPPC2L | -105 |
| STX16 | -33 |
| ULK1 | -26 |
| SPTBN2 | -2 |
| TBC1D1 | 173 |
| KIF15 | 192 |
| BTC | 200 |
| GOSR2 | 228 |
| GABARAPL2 | 266 |
| MADD | 288 |
| VPS28 | 303 |
| TUBA1A | 318 |
| YWHAB | 342 |
| GOLGB1 | 347 |
| SLC18A3 | 483 |
| RIN2 | 492 |
| AP2S1 | 531 |
| SCOC | 533 |
| TF | 580 |
| TUBB3 | 582 |
| DENND4B | 587 |
| LDLR | 643 |
| ADRB2 | 768 |
| STON2 | 825 |
| LMAN2 | 831 |
| MYO6 | 857 |
| FCHO2 | 873 |
| GNS | 893 |
| SNF8 | 927 |
| TBC1D14 | 947 |
| PRKAG2 | 962 |
| GJB4 | 968 |
| ACTR10 | 974 |
| TBC1D10B | 1040 |
| CLVS1 | 1049 |
| TRAPPC9 | 1075 |
| NEDD8 | 1171 |
| AP2B1 | 1177 |
| CYTH2 | 1184 |
| EXOC5 | 1251 |
| RAB3GAP1 | 1266 |
| SPTBN1 | 1334 |
| RABEP1 | 1351 |
| ZW10 | 1362 |
| PACSIN3 | 1467 |
| YWHAH | 1509 |
| AKT2 | 1521 |
| EXOC1 | 1568 |
| TBC1D15 | 1670 |
| GAK | 1686 |
| TUBA1B | 1730 |
| GJB5 | 1745 |
| TRIP10 | 1746 |
| ARF6 | 1750 |
| KIF19 | 1763 |
| RALGAPB | 1774 |
| KIF3B | 1813 |
| RAB1A | 1846 |
| TRAPPC10 | 1857 |
| TXNDC5 | 1866 |
| MYO1C | 1935 |
| ARF4 | 1970 |
| GDI2 | 2006 |
| STX18 | 2110 |
| VPS45 | 2205 |
| GJA3 | 2225 |
| PUM1 | 2246 |
| RALGAPA2 | 2257 |
| BET1L | 2274 |
| GJB3 | 2308 |
| RAB8B | 2313 |
| KIF18B | 2318 |
| KIF27 | 2407 |
| TRAPPC6B | 2427 |
| AP2M1 | 2466 |
| ITSN2 | 2487 |
| AP2A1 | 2500 |
| SYT11 | 2554 |
| GJD2 | 2567 |
| COPZ2 | 2581 |
| ACTR2 | 2584 |
| TRAPPC12 | 2618 |
| TRAPPC1 | 2657 |
| ARRB1 | 2670 |
| VAMP8 | 2687 |
| PRKAB2 | 2720 |
| TSC1 | 2738 |
| CLTA | 2780 |
| SAR1B | 2783 |
| KIF26A | 2813 |
| RAB5C | 2816 |
| FZD4 | 2821 |
| ARCN1 | 2823 |
| SH3GL2 | 2868 |
| CHMP6 | 2869 |
| TSG101 | 2886 |
| TRAPPC4 | 2887 |
| KIF26B | 2924 |
| NAA30 | 2931 |
| COPG2 | 2943 |
| ARRB2 | 3002 |
| GGA3 | 3012 |
| RAB10 | 3030 |
| TUBB2A | 3132 |
| MAN1A2 | 3134 |
| GABARAP | 3191 |
| KIF20A | 3416 |
| BET1 | 3427 |
| KIF3C | 3485 |
| SLC2A4 | 3489 |
| ARPC5 | 3563 |
| GJB7 | 3606 |
| TMED3 | 3623 |
| CHMP4C | 3664 |
| KIFAP3 | 3729 |
| SEC24D | 3822 |
| COPE | 3857 |
| TUBAL3 | 3868 |
| COG3 | 3916 |
| HPS4 | 3993 |
| EPN1 | 3995 |
| RAB14 | 4054 |
| RAB5B | 4118 |
| COPS4 | 4123 |
| KIF2C | 4126 |
| SYT2 | 4153 |
| GGA1 | 4179 |
| HSPA8 | 4201 |
| AP3B1 | 4209 |
| SEC16A | 4216 |
| TRAPPC13 | 4264 |
| MAP1LC3B | 4309 |
| GJA10 | 4313 |
| GJA8 | 4354 |
| KIF11 | 4363 |
| ITSN1 | 4396 |
| EGFR | 4403 |
| CALM1 | 4408 |
| AGPAT3 | 4416 |
| AKT3 | 4420 |
| EXOC8 | 4495 |
| UBQLN1 | 4549 |
| BLOC1S6 | 4644 |
| ACTR3 | 4677 |
| RAB6B | 4733 |
| RAB38 | 4735 |
| COPA | 4736 |
| RABGEF1 | 4747 |
| EREG | 4801 |
| VAMP4 | 4827 |
| TBC1D4 | 4831 |
| MAN2A2 | 4938 |
| MVB12B | 5003 |
| COG6 | 5046 |
| EGF | 5066 |
| NAA38 | 5236 |
| VAMP3 | 5261 |
| DNM2 | 5273 |
| TBC1D10A | 5326 |
| TUBB1 | 5346 |
| RAB3IP | 5348 |
| LRP2 | 5409 |
| NAPG | 5432 |
| SNAP91 | 5441 |
| SEC24C | 5488 |
| RAB27B | 5590 |
| PRKAB1 | 5642 |
| RAB27A | 5652 |
| DENND3 | 5653 |
| STX4 | 5678 |
| CHMP5 | 5701 |
| COPS7B | 5746 |
| GRB2 | 5787 |
| MYH9 | 5790 |
| GOLIM4 | 5821 |
| USO1 | 5838 |
| AMPH | 5858 |
| CHMP3 | 5881 |
| GJB6 | 5886 |
| MYO5A | 5901 |
| SYT1 | 6001 |
| ACTB | 6012 |
| BICD2 | 6082 |
| PAFAH1B2 | 6094 |
| RIN3 | 6109 |
| DENND6B | 6112 |
| SBF1 | 6198 |
| TUBA3C | 6217 |
| DCTN1 | 6219 |
| PRKAA2 | 6287 |
| RAB33B | 6369 |
| EXOC7 | 6376 |
| SGIP1 | 6415 |
| PLA2G4A | 6436 |
| CTTN | 6440 |
| RAB32 | 6447 |
| COL7A1 | 6457 |
| TRAPPC5 | 6630 |
| DCTN3 | 6735 |
| ALS2 | 6763 |
| AP1S3 | 6802 |
| SNX18 | 6854 |
| RAB8A | 7033 |
| CD55 | 7097 |
| WNT5A | 7123 |
| CTSC | 7289 |
| KIF5A | 7357 |
| PPP6C | 7462 |
| SPTA1 | 7519 |
| AKT1 | 7547 |
| TMED7 | 7548 |
| TUBB6 | 7617 |
| CLVS2 | 7743 |
| ALS2CL | 7764 |
| RHOQ | 7811 |
| SPTB | 7879 |
| UBA52 | 7910 |
| APOB | 7935 |
| FNBP1L | 7988 |
| RAB35 | 7994 |
| TUBB2B | 8061 |
| DENND2C | 8216 |
| TOR1A | 8291 |
| SPTBN5 | 8293 |
| INS | 8351 |
| SYS1 | 8396 |
| TUBA3E | 8431 |
| RINL | 8437 |
| BNIP1 | 8529 |
| PRKAG3 | 8602 |
| TUBA8 | 8640 |
| DYNLL2 | 8677 |
| CFTR | 8755 |
| CNIH3 | 8778 |
| DAB2 | 8933 |
| TBC1D10C | 8945 |
| PREB | 9078 |
| ARF5 | 9302 |
| DENND2D | 9323 |
| CD3G | 9577 |
| KIF12 | 9615 |
| CHML | 9731 |
| GJA4 | 9928 |
| CD3D | 9965 |
| IL7R | 9967 |
REACTOME_ADRENOCEPTORS
| 657 | |
|---|---|
| set | REACTOME_ADRENOCEPTORS |
| setSize | 9 |
| pANOVA | 0.0209 |
| s.dist | 0.445 |
| p.adjustANOVA | 0.718 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| ADRA2C | 9020 |
| ADRA1B | 9009 |
| ADRA1A | 8688 |
| ADRA2A | 7409 |
| ADRA2B | 4418 |
| ADRB3 | 2878 |
| ADRB2 | 768 |
| ADRA1D | 722 |
| ADRB1 | -6400 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ADRA2C | 9020 |
| ADRA1B | 9009 |
| ADRA1A | 8688 |
| ADRA2A | 7409 |
| ADRA2B | 4418 |
| ADRB3 | 2878 |
| ADRB2 | 768 |
| ADRA1D | 722 |
| ADRB1 | -6400 |
REACTOME_SYNTHESIS_OF_ACTIVE_UBIQUITIN_ROLES_OF_E1_AND_E2_ENZYMES
| 1249 | |
|---|---|
| set | REACTOME_SYNTHESIS_OF_ACTIVE_UBIQUITIN_ROLES_OF_E1_AND_E2_ENZYMES |
| setSize | 27 |
| pANOVA | 0.021 |
| s.dist | -0.257 |
| p.adjustANOVA | 0.718 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| UBE2E3 | -10821 |
| UBE2E1 | -10694 |
| UBE2S | -10441 |
| UBE2G1 | -9475 |
| USP5 | -9202 |
| UBA6 | -9129 |
| UBB | -8790 |
| UBE2H | -8268 |
| UBE2Q2 | -7895 |
| UBE2W | -7697 |
| OTULIN | -5424 |
| UBE2B | -5041 |
| UBE2R2 | -4758 |
| UBC | -3960 |
| UBE2K | -3457 |
| RPS27A | -3374 |
| UBE2Z | -3125 |
| UBE2C | -3089 |
| UBE2T | -1013 |
| UBE2G2 | -598 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| UBE2E3 | -10821 |
| UBE2E1 | -10694 |
| UBE2S | -10441 |
| UBE2G1 | -9475 |
| USP5 | -9202 |
| UBA6 | -9129 |
| UBB | -8790 |
| UBE2H | -8268 |
| UBE2Q2 | -7895 |
| UBE2W | -7697 |
| OTULIN | -5424 |
| UBE2B | -5041 |
| UBE2R2 | -4758 |
| UBC | -3960 |
| UBE2K | -3457 |
| RPS27A | -3374 |
| UBE2Z | -3125 |
| UBE2C | -3089 |
| UBE2T | -1013 |
| UBE2G2 | -598 |
| UBE2D1 | 455 |
| UCHL3 | 1241 |
| UBE2L3 | 2027 |
| USP7 | 3204 |
| UBE2D2 | 4781 |
| UBA52 | 7910 |
| CDC34 | 7992 |
REACTOME_TFAP2_AP_2_FAMILY_REGULATES_TRANSCRIPTION_OF_GROWTH_FACTORS_AND_THEIR_RECEPTORS
| 1253 | |
|---|---|
| set | REACTOME_TFAP2_AP_2_FAMILY_REGULATES_TRANSCRIPTION_OF_GROWTH_FACTORS_AND_THEIR_RECEPTORS |
| setSize | 14 |
| pANOVA | 0.0223 |
| s.dist | 0.353 |
| p.adjustANOVA | 0.724 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CGB5 | 9824 |
| CGA | 8227 |
| CGB8 | 7586 |
| KIT | 7154 |
| TFAP2C | 4981 |
| EGFR | 4403 |
| VEGFA | 4305 |
| ESR1 | 3701 |
| ATAD2 | 2398 |
| TFAP2B | 401 |
| ERBB2 | -31 |
| TGFA | -493 |
| TFAP2A | -1823 |
| YY1 | -8000 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CGB5 | 9824 |
| CGA | 8227 |
| CGB8 | 7586 |
| KIT | 7154 |
| TFAP2C | 4981 |
| EGFR | 4403 |
| VEGFA | 4305 |
| ESR1 | 3701 |
| ATAD2 | 2398 |
| TFAP2B | 401 |
| ERBB2 | -31 |
| TGFA | -493 |
| TFAP2A | -1823 |
| YY1 | -8000 |
REACTOME_DUAL_INCISION_IN_GG_NER
| 1023 | |
|---|---|
| set | REACTOME_DUAL_INCISION_IN_GG_NER |
| setSize | 39 |
| pANOVA | 0.0224 |
| s.dist | -0.211 |
| p.adjustANOVA | 0.724 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| POLD4 | -11002 |
| POLE2 | -10034 |
| ERCC1 | -9751 |
| RBX1 | -9464 |
| XPA | -9331 |
| UBB | -8790 |
| ERCC2 | -8731 |
| RPA2 | -8723 |
| POLE4 | -7226 |
| CHD1L | -7214 |
| POLE | -6849 |
| ERCC5 | -6626 |
| RFC1 | -6180 |
| POLD2 | -5763 |
| POLK | -5451 |
| POLD3 | -5248 |
| PARP2 | -5213 |
| RFC5 | -4967 |
| GTF2H4 | -4904 |
| GTF2H3 | -4677 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| POLD4 | -11002 |
| POLE2 | -10034 |
| ERCC1 | -9751 |
| RBX1 | -9464 |
| XPA | -9331 |
| UBB | -8790 |
| ERCC2 | -8731 |
| RPA2 | -8723 |
| POLE4 | -7226 |
| CHD1L | -7214 |
| POLE | -6849 |
| ERCC5 | -6626 |
| RFC1 | -6180 |
| POLD2 | -5763 |
| POLK | -5451 |
| POLD3 | -5248 |
| PARP2 | -5213 |
| RFC5 | -4967 |
| GTF2H4 | -4904 |
| GTF2H3 | -4677 |
| UBC | -3960 |
| RPS27A | -3374 |
| ERCC4 | -3337 |
| GTF2H5 | -3048 |
| RPA3 | -2234 |
| RPA1 | -1871 |
| POLE3 | -631 |
| DDB1 | -236 |
| RFC3 | 262 |
| RFC2 | 597 |
| DDB2 | 1053 |
| POLD1 | 1996 |
| ERCC3 | 3005 |
| PCNA | 3188 |
| CUL4A | 3629 |
| RFC4 | 4373 |
| GTF2H1 | 6412 |
| UBA52 | 7910 |
| PARP1 | 9425 |
Here is the session info with all the versions of packages used.
sessionInfo()## R version 4.3.2 (2023-10-31)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.3 LTS
##
## Matrix products: default
## BLAS: /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so; LAPACK version 3.10.0
##
## locale:
## [1] LC_CTYPE=en_US.UTF-8 LC_NUMERIC=C
## [3] LC_TIME=en_US.UTF-8 LC_COLLATE=en_US.UTF-8
## [5] LC_MONETARY=en_US.UTF-8 LC_MESSAGES=en_US.UTF-8
## [7] LC_PAPER=en_US.UTF-8 LC_NAME=C
## [9] LC_ADDRESS=C LC_TELEPHONE=C
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C
##
## time zone: Etc/UTC
## tzcode source: system (glibc)
##
## attached base packages:
## [1] parallel stats4 stats graphics grDevices utils datasets
## [8] methods base
##
## other attached packages:
## [1] pkgload_1.3.3
## [2] GGally_2.2.0
## [3] ggplot2_3.4.4
## [4] reshape2_1.4.4
## [5] gtools_3.9.5
## [6] tibble_3.2.1
## [7] dplyr_1.1.4
## [8] echarts4r_0.4.5
## [9] png_0.1-8
## [10] gridExtra_2.3
## [11] missMethyl_1.36.0
## [12] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.1
## [13] beeswarm_0.4.0
## [14] kableExtra_1.3.4
## [15] gplots_3.1.3
## [16] mitch_1.15.0
## [17] tictoc_1.2
## [18] HGNChelper_0.8.1
## [19] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [20] IlluminaHumanMethylation450kmanifest_0.4.0
## [21] minfi_1.48.0
## [22] bumphunter_1.44.0
## [23] locfit_1.5-9.8
## [24] iterators_1.0.14
## [25] foreach_1.5.2
## [26] Biostrings_2.70.1
## [27] XVector_0.42.0
## [28] SummarizedExperiment_1.32.0
## [29] Biobase_2.62.0
## [30] MatrixGenerics_1.14.0
## [31] matrixStats_1.2.0
## [32] GenomicRanges_1.54.1
## [33] GenomeInfoDb_1.38.2
## [34] IRanges_2.36.0
## [35] S4Vectors_0.40.2
## [36] BiocGenerics_0.48.1
## [37] eulerr_7.0.0
## [38] limma_3.58.1
##
## loaded via a namespace (and not attached):
## [1] splines_4.3.2 later_1.3.2
## [3] BiocIO_1.12.0 bitops_1.0-7
## [5] filelock_1.0.3 preprocessCore_1.64.0
## [7] XML_3.99-0.16 lifecycle_1.0.4
## [9] lattice_0.22-5 MASS_7.3-60
## [11] base64_2.0.1 scrime_1.3.5
## [13] magrittr_2.0.3 sass_0.4.8
## [15] rmarkdown_2.25 jquerylib_0.1.4
## [17] yaml_2.3.8 httpuv_1.6.13
## [19] doRNG_1.8.6 askpass_1.2.0
## [21] DBI_1.1.3 RColorBrewer_1.1-3
## [23] abind_1.4-5 zlibbioc_1.48.0
## [25] rvest_1.0.3 quadprog_1.5-8
## [27] purrr_1.0.2 RCurl_1.98-1.13
## [29] rappdirs_0.3.3 GenomeInfoDbData_1.2.11
## [31] genefilter_1.84.0 annotate_1.80.0
## [33] svglite_2.1.3 DelayedMatrixStats_1.24.0
## [35] codetools_0.2-19 DelayedArray_0.28.0
## [37] xml2_1.3.6 tidyselect_1.2.0
## [39] beanplot_1.3.1 BiocFileCache_2.10.1
## [41] webshot_0.5.5 illuminaio_0.44.0
## [43] GenomicAlignments_1.38.0 jsonlite_1.8.8
## [45] multtest_2.58.0 ellipsis_0.3.2
## [47] survival_3.5-7 systemfonts_1.0.5
## [49] tools_4.3.2 progress_1.2.3
## [51] Rcpp_1.0.11 glue_1.6.2
## [53] SparseArray_1.2.2 xfun_0.41
## [55] HDF5Array_1.30.0 withr_2.5.2
## [57] fastmap_1.1.1 rhdf5filters_1.14.1
## [59] fansi_1.0.6 openssl_2.1.1
## [61] caTools_1.18.2 digest_0.6.33
## [63] R6_2.5.1 mime_0.12
## [65] colorspace_2.1-0 biomaRt_2.58.0
## [67] RSQLite_2.3.4 utf8_1.2.4
## [69] tidyr_1.3.0 generics_0.1.3
## [71] data.table_1.14.10 rtracklayer_1.62.0
## [73] prettyunits_1.2.0 httr_1.4.7
## [75] htmlwidgets_1.6.4 S4Arrays_1.2.0
## [77] ggstats_0.5.1 pkgconfig_2.0.3
## [79] gtable_0.3.4 blob_1.2.4
## [81] siggenes_1.76.0 htmltools_0.5.7
## [83] scales_1.3.0 rstudioapi_0.15.0
## [85] knitr_1.45 tzdb_0.4.0
## [87] rjson_0.2.21 nlme_3.1-163
## [89] curl_5.2.0 org.Hs.eg.db_3.18.0
## [91] cachem_1.0.8 rhdf5_2.46.1
## [93] stringr_1.5.1 KernSmooth_2.23-22
## [95] AnnotationDbi_1.64.1 restfulr_0.0.15
## [97] GEOquery_2.70.0 pillar_1.9.0
## [99] grid_4.3.2 reshape_0.8.9
## [101] vctrs_0.6.5 promises_1.2.1
## [103] dbplyr_2.4.0 xtable_1.8-4
## [105] evaluate_0.23 readr_2.1.4
## [107] GenomicFeatures_1.54.1 cli_3.6.2
## [109] compiler_4.3.2 Rsamtools_2.18.0
## [111] rlang_1.1.2 crayon_1.5.2
## [113] rngtools_1.5.2 nor1mix_1.3-2
## [115] mclust_6.0.1 plyr_1.8.9
## [117] stringi_1.8.3 viridisLite_0.4.2
## [119] BiocParallel_1.36.0 munsell_0.5.0
## [121] Matrix_1.6-1.1 hms_1.1.3
## [123] sparseMatrixStats_1.14.0 bit64_4.0.5
## [125] Rhdf5lib_1.24.1 KEGGREST_1.42.0
## [127] statmod_1.5.0 shiny_1.8.0
## [129] highr_0.10 memoise_2.0.1
## [131] bslib_0.6.1 bit_4.0.5END of report