date generated: 2024-01-18

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch
x
A1BG 0.0017412
A1BG-AS1 0.0022726
A1CF -0.0002604
A2M -0.0015433
A2M-AS1 -0.0101360
A2ML1 0.0017476

Here are some metrics about the input data profile:

Profiling data metrics
Profile metrics
num_genesets 1654
num_genes_in_profile 22007
duplicated_genes_present 0
num_profile_genes_in_sets 10383
num_profile_genes_not_in_sets 11624

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets: c2.cp.reactome.v2023.1.Hs.symbols.gmt
Gene set metrics
Gene sets metrics
num_genesets 1654
num_genesets_excluded 365
num_genesets_included 1289

Differential pathway expression


Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

## Warning in kable_styling(., "hover", full_width = FALSE): Please specify format
## in kable. kableExtra can customize either HTML or LaTeX outputs. See
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set setSize pANOVA s.dist p.adjustANOVA
REACTOME METABOLISM OF RNA 675 1.68e-31 -0.263 2.76e-28
REACTOME RNA POLYMERASE II TRANSCRIPTION 1336 4.99e-29 -0.182 4.10e-26
REACTOME CELL CYCLE 666 1.19e-28 -0.252 6.54e-26
REACTOME CELL CYCLE MITOTIC 539 4.03e-27 -0.271 1.65e-24
REACTOME M PHASE 398 6.42e-20 -0.267 2.11e-17
REACTOME CELLULAR RESPONSES TO STIMULI 779 9.35e-20 -0.191 2.56e-17
REACTOME DNA REPAIR 321 2.44e-16 -0.266 5.72e-14
REACTOME INFECTIOUS DISEASE 910 2.01e-15 -0.155 4.13e-13
REACTOME DNA REPLICATION 178 4.13e-15 -0.341 7.53e-13
REACTOME CELL CYCLE CHECKPOINTS 284 1.29e-14 -0.266 2.11e-12
REACTOME CHROMATIN MODIFYING ENZYMES 252 5.53e-14 -0.275 8.25e-12
REACTOME FORMATION OF THE CORNIFIED ENVELOPE 125 1.06e-13 0.385 1.45e-11
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1 229 1.18e-13 -0.284 1.49e-11
REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 100 1.42e-13 -0.428 1.66e-11
REACTOME HATS ACETYLATE HISTONES 129 1.54e-13 -0.376 1.69e-11
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION 138 1.82e-13 -0.363 1.87e-11
REACTOME DEUBIQUITINATION 260 2.30e-13 -0.264 2.22e-11
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS 121 3.61e-13 -0.382 3.30e-11
REACTOME CELLULAR SENESCENCE 189 8.16e-13 -0.302 7.05e-11
REACTOME GPCR LIGAND BINDING 444 1.06e-12 0.197 8.72e-11
REACTOME DNA REPLICATION PRE INITIATION 150 2.44e-12 -0.331 1.91e-10
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA 263 2.97e-12 -0.250 2.18e-10
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION 1356 3.06e-12 -0.113 2.18e-10
REACTOME HDACS DEACETYLATE HISTONES 85 4.55e-12 -0.434 3.11e-10
REACTOME UB SPECIFIC PROCESSING PROTEASES 187 4.86e-12 -0.293 3.20e-10
REACTOME SIGNALING BY GPCR 673 8.80e-12 0.154 5.55e-10
REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS 83 1.16e-11 -0.431 7.07e-10
REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION 90 1.87e-11 -0.409 1.10e-09
REACTOME TRANSCRIPTIONAL REGULATION BY TP53 351 2.00e-11 -0.208 1.14e-09
REACTOME RNA POLYMERASE I PROMOTER ESCAPE 83 4.13e-11 -0.419 2.22e-09
REACTOME MRNA SPLICING 197 4.24e-11 -0.272 2.22e-09
REACTOME S PHASE 159 4.32e-11 -0.303 2.22e-09
REACTOME RNA POLYMERASE I TRANSCRIPTION 102 7.85e-11 -0.372 3.91e-09
REACTOME HCMV LATE EVENTS 110 8.83e-11 -0.358 4.27e-09
REACTOME MUSCLE CONTRACTION 197 1.08e-10 0.267 5.06e-09
REACTOME MITOTIC PROPHASE 134 1.23e-10 -0.322 5.61e-09
REACTOME OXIDATIVE STRESS INDUCED SENESCENCE 118 4.17e-10 -0.333 1.85e-08
REACTOME HCMV INFECTION 152 7.74e-10 -0.289 3.35e-08
REACTOME PRC2 METHYLATES HISTONES AND DNA 65 8.49e-10 -0.440 3.58e-08
REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS 113 1.27e-09 -0.330 5.22e-08
REACTOME RHO GTPASE EFFECTORS 305 1.36e-09 -0.202 5.43e-08
REACTOME MITOTIC METAPHASE AND ANAPHASE 228 1.77e-09 -0.231 6.89e-08
REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS 312 1.80e-09 0.198 6.89e-08
REACTOME DISEASES OF PROGRAMMED CELL DEATH 96 1.99e-09 -0.354 7.26e-08
REACTOME CHROMOSOME MAINTENANCE 130 1.99e-09 -0.305 7.26e-08
REACTOME PEPTIDE LIGAND BINDING RECEPTORS 188 2.34e-09 0.252 8.34e-08
REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION 84 3.46e-09 -0.373 1.21e-07
REACTOME ESTROGEN DEPENDENT GENE EXPRESSION 140 3.82e-09 -0.288 1.31e-07
REACTOME RRNA PROCESSING 192 4.42e-09 -0.245 1.46e-07
REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION 60 4.43e-09 -0.438 1.46e-07


Results (complete table)


Click HERE to show results for all gene sets

Complete results
set setSize pANOVA s.dist p.adjustANOVA
REACTOME METABOLISM OF RNA 675 1.68e-31 -0.263000 2.76e-28
REACTOME RNA POLYMERASE II TRANSCRIPTION 1336 4.99e-29 -0.182000 4.10e-26
REACTOME CELL CYCLE 666 1.19e-28 -0.252000 6.54e-26
REACTOME CELL CYCLE MITOTIC 539 4.03e-27 -0.271000 1.65e-24
REACTOME M PHASE 398 6.42e-20 -0.267000 2.11e-17
REACTOME CELLULAR RESPONSES TO STIMULI 779 9.35e-20 -0.191000 2.56e-17
REACTOME DNA REPAIR 321 2.44e-16 -0.266000 5.72e-14
REACTOME INFECTIOUS DISEASE 910 2.01e-15 -0.155000 4.13e-13
REACTOME DNA REPLICATION 178 4.13e-15 -0.341000 7.53e-13
REACTOME CELL CYCLE CHECKPOINTS 284 1.29e-14 -0.266000 2.11e-12
REACTOME CHROMATIN MODIFYING ENZYMES 252 5.53e-14 -0.275000 8.25e-12
REACTOME FORMATION OF THE CORNIFIED ENVELOPE 125 1.06e-13 0.385000 1.45e-11
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1 229 1.18e-13 -0.284000 1.49e-11
REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 100 1.42e-13 -0.428000 1.66e-11
REACTOME HATS ACETYLATE HISTONES 129 1.54e-13 -0.376000 1.69e-11
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION 138 1.82e-13 -0.363000 1.87e-11
REACTOME DEUBIQUITINATION 260 2.30e-13 -0.264000 2.22e-11
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS 121 3.61e-13 -0.382000 3.30e-11
REACTOME CELLULAR SENESCENCE 189 8.16e-13 -0.302000 7.05e-11
REACTOME GPCR LIGAND BINDING 444 1.06e-12 0.197000 8.72e-11
REACTOME DNA REPLICATION PRE INITIATION 150 2.44e-12 -0.331000 1.91e-10
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA 263 2.97e-12 -0.250000 2.18e-10
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION 1356 3.06e-12 -0.113000 2.18e-10
REACTOME HDACS DEACETYLATE HISTONES 85 4.55e-12 -0.434000 3.11e-10
REACTOME UB SPECIFIC PROCESSING PROTEASES 187 4.86e-12 -0.293000 3.20e-10
REACTOME SIGNALING BY GPCR 673 8.80e-12 0.154000 5.55e-10
REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS 83 1.16e-11 -0.431000 7.07e-10
REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION 90 1.87e-11 -0.409000 1.10e-09
REACTOME TRANSCRIPTIONAL REGULATION BY TP53 351 2.00e-11 -0.208000 1.14e-09
REACTOME RNA POLYMERASE I PROMOTER ESCAPE 83 4.13e-11 -0.419000 2.22e-09
REACTOME MRNA SPLICING 197 4.24e-11 -0.272000 2.22e-09
REACTOME S PHASE 159 4.32e-11 -0.303000 2.22e-09
REACTOME RNA POLYMERASE I TRANSCRIPTION 102 7.85e-11 -0.372000 3.91e-09
REACTOME HCMV LATE EVENTS 110 8.83e-11 -0.358000 4.27e-09
REACTOME MUSCLE CONTRACTION 197 1.08e-10 0.267000 5.06e-09
REACTOME MITOTIC PROPHASE 134 1.23e-10 -0.322000 5.61e-09
REACTOME OXIDATIVE STRESS INDUCED SENESCENCE 118 4.17e-10 -0.333000 1.85e-08
REACTOME HCMV INFECTION 152 7.74e-10 -0.289000 3.35e-08
REACTOME PRC2 METHYLATES HISTONES AND DNA 65 8.49e-10 -0.440000 3.58e-08
REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS 113 1.27e-09 -0.330000 5.22e-08
REACTOME RHO GTPASE EFFECTORS 305 1.36e-09 -0.202000 5.43e-08
REACTOME MITOTIC METAPHASE AND ANAPHASE 228 1.77e-09 -0.231000 6.89e-08
REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS 312 1.80e-09 0.198000 6.89e-08
REACTOME DISEASES OF PROGRAMMED CELL DEATH 96 1.99e-09 -0.354000 7.26e-08
REACTOME CHROMOSOME MAINTENANCE 130 1.99e-09 -0.305000 7.26e-08
REACTOME PEPTIDE LIGAND BINDING RECEPTORS 188 2.34e-09 0.252000 8.34e-08
REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION 84 3.46e-09 -0.373000 1.21e-07
REACTOME ESTROGEN DEPENDENT GENE EXPRESSION 140 3.82e-09 -0.288000 1.31e-07
REACTOME RRNA PROCESSING 192 4.42e-09 -0.245000 1.46e-07
REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION 60 4.43e-09 -0.438000 1.46e-07
REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION 62 5.15e-09 -0.429000 1.66e-07
REACTOME HCMV EARLY EVENTS 128 5.33e-09 -0.299000 1.68e-07
REACTOME TRANSLATION 278 5.53e-09 -0.203000 1.69e-07
REACTOME HIV INFECTION 223 5.54e-09 -0.226000 1.69e-07
REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 98 5.80e-09 -0.340000 1.73e-07
REACTOME G2 M CHECKPOINTS 162 6.01e-09 -0.265000 1.76e-07
REACTOME HOMOLOGY DIRECTED REPAIR 132 6.21e-09 -0.293000 1.79e-07
REACTOME TELOMERE MAINTENANCE 106 1.20e-08 -0.320000 3.41e-07
REACTOME CONDENSATION OF PROPHASE CHROMOSOMES 66 1.31e-08 -0.404000 3.66e-07
REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3 679 1.64e-08 -0.127000 4.48e-07
REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP 104 1.82e-08 -0.319000 4.90e-07
REACTOME SEPARATION OF SISTER CHROMATIDS 184 2.11e-08 -0.239000 5.60e-07
REACTOME SYNTHESIS OF DNA 119 2.59e-08 -0.295000 6.75e-07
REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS 100 2.69e-08 -0.322000 6.89e-07
REACTOME GENE SILENCING BY RNA 133 2.75e-08 -0.279000 6.95e-07
REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3 59 2.88e-08 -0.417000 7.17e-07
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION 361 3.27e-08 -0.169000 8.00e-07
REACTOME DNA DOUBLE STRAND BREAK REPAIR 162 4.60e-08 -0.249000 1.11e-06
REACTOME DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE 76 5.44e-08 -0.361000 1.29e-06
REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION 68 6.29e-08 -0.379000 1.47e-06
REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION 145 6.98e-08 -0.259000 1.62e-06
REACTOME EXTRACELLULAR MATRIX ORGANIZATION 291 7.99e-08 0.183000 1.82e-06
REACTOME DNA METHYLATION 58 9.86e-08 -0.404000 2.22e-06
REACTOME KERATINIZATION 210 1.12e-07 0.212000 2.49e-06
REACTOME SIGNALING BY NOTCH 234 1.44e-07 -0.200000 3.16e-06
REACTOME MITOTIC G2 G2 M PHASES 194 1.55e-07 -0.218000 3.36e-06
REACTOME UCH PROTEINASES 99 1.71e-07 -0.304000 3.66e-06
REACTOME CARDIAC CONDUCTION 125 1.79e-07 0.270000 3.78e-06
REACTOME MEIOTIC RECOMBINATION 80 1.82e-07 -0.337000 3.78e-06
REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS 86 2.02e-07 -0.324000 4.13e-06
REACTOME TRANSPORT OF SMALL MOLECULES 697 2.04e-07 0.115000 4.13e-06
REACTOME CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY 84 2.23e-07 -0.327000 4.46e-06
REACTOME PROCESSING OF DNA DOUBLE STRAND BREAK ENDS 93 2.31e-07 -0.310000 4.56e-06
REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER 81 2.33e-07 -0.332000 4.56e-06
REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT 236 2.97e-07 0.194000 5.69e-06
REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE 66 2.98e-07 -0.365000 5.69e-06
REACTOME PROGRAMMED CELL DEATH 204 3.01e-07 -0.208000 5.69e-06
REACTOME NEUTROPHIL DEGRANULATION 460 3.64e-07 -0.138000 6.79e-06
REACTOME NUCLEOTIDE EXCISION REPAIR 107 3.70e-07 -0.284000 6.82e-06
REACTOME PRE NOTCH EXPRESSION AND PROCESSING 112 3.92e-07 -0.277000 7.16e-06
REACTOME NEURONAL SYSTEM 388 4.53e-07 0.149000 8.18e-06
REACTOME MITOTIC PROMETAPHASE 194 5.23e-07 -0.209000 9.34e-06
REACTOME BASE EXCISION REPAIR 87 6.22e-07 -0.309000 1.10e-05
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES 55 7.02e-07 0.387000 1.23e-05
REACTOME MEIOSIS 110 8.44e-07 -0.272000 1.46e-05
REACTOME ESR MEDIATED SIGNALING 210 9.33e-07 -0.196000 1.60e-05
REACTOME SARS COV INFECTIONS 392 1.13e-06 -0.143000 1.92e-05
REACTOME RHO GTPASES ACTIVATE PKNS 86 1.19e-06 -0.303000 1.99e-05
REACTOME ASPARAGINE N LINKED GLYCOSYLATION 299 1.34e-06 -0.162000 2.22e-05
REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE 277 1.37e-06 -0.169000 2.26e-05
REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION 296 1.75e-06 -0.161000 2.85e-05
REACTOME HIV LIFE CYCLE 145 2.01e-06 -0.229000 3.21e-05
REACTOME MITOTIC SPINDLE CHECKPOINT 109 2.01e-06 -0.263000 3.21e-05
REACTOME G ALPHA I SIGNALLING EVENTS 304 2.19e-06 0.158000 3.45e-05
REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS 188 2.34e-06 -0.200000 3.65e-05
REACTOME MEMBRANE TRAFFICKING 603 2.49e-06 -0.112000 3.85e-05
REACTOME POTASSIUM CHANNELS 102 2.68e-06 0.269000 4.11e-05
REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE 63 2.82e-06 -0.341000 4.29e-05
REACTOME BASE EXCISION REPAIR AP SITE FORMATION 59 3.05e-06 -0.351000 4.59e-05
REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE 52 3.10e-06 -0.374000 4.60e-05
REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC 198 3.11e-06 -0.192000 4.60e-05
REACTOME KEAP1 NFE2L2 PATHWAY 104 3.30e-06 -0.264000 4.84e-05
REACTOME NONHOMOLOGOUS END JOINING NHEJ 64 3.70e-06 -0.334000 5.38e-05
REACTOME SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE 91 4.03e-06 -0.280000 5.80e-05
REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION 183 4.35e-06 -0.197000 6.21e-05
REACTOME INNATE IMMUNE SYSTEM 1002 5.17e-06 -0.085100 7.31e-05
REACTOME DEADENYLATION DEPENDENT MRNA DECAY 56 6.59e-06 -0.348000 9.25e-05
REACTOME G2 M DNA DAMAGE CHECKPOINT 90 8.80e-06 -0.271000 1.23e-04
REACTOME SUMOYLATION 179 9.07e-06 -0.192000 1.25e-04
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS 161 1.07e-05 -0.201000 1.46e-04
REACTOME FC EPSILON RECEPTOR FCERI SIGNALING 127 1.08e-05 -0.226000 1.46e-04
REACTOME G ALPHA S SIGNALLING EVENTS 155 1.09e-05 0.205000 1.46e-04
REACTOME VESICLE MEDIATED TRANSPORT 642 1.29e-05 -0.101000 1.73e-04
REACTOME MEIOTIC SYNAPSIS 73 1.38e-05 -0.294000 1.82e-04
REACTOME PTEN REGULATION 135 1.51e-05 -0.216000 1.98e-04
REACTOME REGULATION OF TP53 ACTIVITY 156 1.72e-05 -0.199000 2.24e-04
REACTOME HOST INTERACTIONS OF HIV FACTORS 127 1.74e-05 -0.221000 2.25e-04
REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT 222 1.97e-05 -0.166000 2.53e-04
REACTOME APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS 87 2.24e-05 -0.263000 2.86e-04
REACTOME APOPTOSIS 173 2.64e-05 -0.185000 3.34e-04
REACTOME SARS COV 1 INFECTION 136 2.84e-05 -0.208000 3.56e-04
REACTOME REPRODUCTION 136 2.87e-05 -0.208000 3.57e-04
REACTOME ER TO GOLGI ANTEROGRADE TRANSPORT 152 2.92e-05 -0.196000 3.60e-04
REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS 418 3.06e-05 -0.119000 3.75e-04
REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR 79 3.44e-05 -0.270000 4.16e-04
REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS 93 3.45e-05 0.248000 4.16e-04
REACTOME RMTS METHYLATE HISTONE ARGININES 72 3.68e-05 -0.281000 4.41e-04
REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 73 3.72e-05 -0.279000 4.42e-04
REACTOME CILIUM ASSEMBLY 190 4.03e-05 -0.173000 4.76e-04
REACTOME TRNA PROCESSING 105 4.21e-05 -0.231000 4.93e-04
REACTOME AMYLOID FIBER FORMATION 102 4.60e-05 -0.233000 5.36e-04
REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT 159 5.63e-05 -0.185000 6.51e-04
REACTOME RESOLUTION OF SISTER CHROMATID COHESION 120 5.82e-05 -0.212000 6.68e-04
REACTOME SIGNALING BY THE B CELL RECEPTOR BCR 106 6.47e-05 -0.225000 7.33e-04
REACTOME REGULATION OF PTEN STABILITY AND ACTIVITY 67 6.47e-05 -0.282000 7.33e-04
REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX 85 7.71e-05 -0.248000 8.67e-04
REACTOME PROTEIN UBIQUITINATION 76 7.90e-05 -0.262000 8.82e-04
REACTOME SIGNALING BY NOTCH4 80 7.96e-05 -0.255000 8.82e-04
REACTOME ORC1 REMOVAL FROM CHROMATIN 70 8.00e-05 -0.273000 8.82e-04
REACTOME NEDDYLATION 235 8.66e-05 -0.149000 9.47e-04
REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM 78 9.24e-05 -0.256000 1.00e-03
REACTOME METALLOPROTEASE DUBS 36 9.37e-05 -0.376000 1.01e-03
REACTOME INFLUENZA INFECTION 149 9.69e-05 -0.185000 1.04e-03
REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21 59 1.04e-04 -0.292000 1.11e-03
REACTOME TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER 76 1.15e-04 -0.256000 1.22e-03
REACTOME PD 1 SIGNALING 21 1.22e-04 0.484000 1.28e-03
REACTOME SIGNALING BY ALK IN CANCER 53 1.23e-04 -0.305000 1.28e-03
REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE 93 1.25e-04 -0.230000 1.30e-03
REACTOME RNA POLYMERASE II PRE TRANSCRIPTION EVENTS 77 1.29e-04 -0.252000 1.33e-03
REACTOME SIGNALING BY ROBO RECEPTORS 206 1.48e-04 -0.153000 1.52e-03
REACTOME NEGATIVE REGULATION OF NOTCH4 SIGNALING 53 1.59e-04 -0.300000 1.63e-03
REACTOME SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS 74 1.61e-04 -0.254000 1.63e-03
REACTOME AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA 54 1.69e-04 -0.296000 1.69e-03
REACTOME RNA POLYMERASE II TRANSCRIBES SNRNA GENES 77 1.69e-04 -0.248000 1.69e-03
REACTOME MITOCHONDRIAL TRANSLATION 93 1.80e-04 -0.225000 1.80e-03
REACTOME DNA DOUBLE STRAND BREAK RESPONSE 74 1.82e-04 -0.252000 1.80e-03
REACTOME SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA 52 1.86e-04 0.300000 1.83e-03
REACTOME CELLULAR RESPONSE TO STARVATION 147 1.91e-04 -0.178000 1.86e-03
REACTOME FORMATION OF INCISION COMPLEX IN GG NER 40 1.91e-04 -0.341000 1.86e-03
REACTOME NUCLEAR EVENTS MEDIATED BY NFE2L2 77 2.11e-04 -0.244000 2.04e-03
REACTOME SIGNALING BY NUCLEAR RECEPTORS 283 2.15e-04 -0.128000 2.06e-03
REACTOME FGFR1C LIGAND BINDING AND ACTIVATION 11 2.26e-04 0.642000 2.16e-03
REACTOME SARS COV 2 INFECTION 281 2.33e-04 -0.128000 2.20e-03
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR4 14 2.34e-04 0.568000 2.20e-03
REACTOME RHO GTPASES ACTIVATE FORMINS 136 2.41e-04 -0.182000 2.26e-03
REACTOME G1 S DNA DAMAGE CHECKPOINTS 67 2.50e-04 -0.259000 2.33e-03
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES 255 2.51e-04 0.133000 2.33e-03
REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY 72 2.54e-04 -0.249000 2.34e-03
REACTOME TRANSCRIPTIONAL REGULATION BY E2F6 32 2.62e-04 -0.373000 2.40e-03
REACTOME NONSENSE MEDIATED DECAY NMD 107 2.65e-04 -0.204000 2.42e-03
REACTOME TELOMERE C STRAND LAGGING STRAND SYNTHESIS 33 2.72e-04 -0.366000 2.47e-03
REACTOME ADAPTIVE IMMUNE SYSTEM 729 2.94e-04 -0.078700 2.66e-03
REACTOME FATTY ACIDS 15 3.03e-04 0.539000 2.72e-03
REACTOME ANTIGEN PROCESSING CROSS PRESENTATION 98 3.26e-04 -0.210000 2.91e-03
REACTOME SURFACTANT METABOLISM 28 3.48e-04 0.390000 3.09e-03
REACTOME E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS 58 3.50e-04 -0.271000 3.09e-03
REACTOME SENSORY PROCESSING OF SOUND 72 3.54e-04 0.243000 3.10e-03
REACTOME REGULATED NECROSIS 57 3.56e-04 -0.273000 3.10e-03
REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION 62 3.57e-04 -0.262000 3.10e-03
REACTOME ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION 28 3.68e-04 0.389000 3.18e-03
REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF 53 3.93e-04 -0.281000 3.36e-03
REACTOME STRIATED MUSCLE CONTRACTION 35 3.93e-04 0.346000 3.36e-03
REACTOME GABA B RECEPTOR ACTIVATION 43 3.98e-04 0.312000 3.39e-03
REACTOME NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION 193 4.04e-04 0.148000 3.42e-03
REACTOME ION CHANNEL TRANSPORT 172 4.32e-04 0.156000 3.64e-03
REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX 134 4.37e-04 0.176000 3.66e-03
REACTOME DISEASES OF MITOTIC CELL CYCLE 37 4.45e-04 -0.334000 3.71e-03
REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 54 4.69e-04 -0.275000 3.89e-03
REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION 45 5.01e-04 -0.300000 4.13e-03
REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS 18 5.25e-04 -0.472000 4.29e-03
REACTOME FCERI MEDIATED NF KB ACTIVATION 78 5.25e-04 -0.227000 4.29e-03
REACTOME EXTENSION OF TELOMERES 49 5.48e-04 -0.285000 4.46e-03
REACTOME INTERLEUKIN 7 SIGNALING 31 5.51e-04 -0.358000 4.46e-03
REACTOME ECM PROTEOGLYCANS 73 5.61e-04 0.233000 4.51e-03
REACTOME SENSORY PERCEPTION 555 5.76e-04 0.085400 4.61e-03
REACTOME DEGRADATION OF DVL 56 5.81e-04 -0.266000 4.63e-03
REACTOME COLLAGEN FORMATION 88 6.20e-04 0.211000 4.92e-03
REACTOME COPI MEDIATED ANTEROGRADE TRANSPORT 101 6.44e-04 -0.196000 5.09e-03
REACTOME GOLGI TO ER RETROGRADE TRANSPORT 132 6.49e-04 -0.172000 5.10e-03
REACTOME STABILIZATION OF P53 56 6.70e-04 -0.263000 5.24e-03
REACTOME REGULATION OF LIPID METABOLISM BY PPARALPHA 115 6.82e-04 -0.183000 5.30e-03
REACTOME ACYL CHAIN REMODELLING OF PI 17 6.84e-04 0.476000 5.30e-03
REACTOME INWARDLY RECTIFYING K CHANNELS 35 6.98e-04 0.331000 5.38e-03
REACTOME TRANSCRIPTION OF THE HIV GENOME 66 7.38e-04 -0.240000 5.66e-03
REACTOME DUAL INCISION IN TC NER 63 7.41e-04 -0.246000 5.66e-03
REACTOME TRNA PROCESSING IN THE NUCLEUS 58 7.63e-04 -0.255000 5.78e-03
REACTOME POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE 25 7.67e-04 -0.389000 5.78e-03
REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC 28 7.68e-04 -0.367000 5.78e-03
REACTOME HDR THROUGH HOMOLOGOUS RECOMBINATION HRR 66 7.70e-04 -0.239000 5.78e-03
REACTOME DUAL INCISION IN GG NER 39 8.35e-04 -0.309000 6.22e-03
REACTOME EICOSANOIDS 12 8.37e-04 0.557000 6.22e-03
REACTOME DEGRADATION OF GLI1 BY THE PROTEASOME 59 8.43e-04 -0.251000 6.23e-03
REACTOME HDR THROUGH SINGLE STRAND ANNEALING SSA 37 8.61e-04 -0.317000 6.34e-03
REACTOME FGFR2C LIGAND BINDING AND ACTIVATION 12 9.11e-04 0.553000 6.68e-03
REACTOME SIGNALING BY FLT3 FUSION PROTEINS 19 9.66e-04 -0.437000 7.05e-03
REACTOME METABOLISM OF POLYAMINES 56 9.79e-04 -0.255000 7.11e-03
REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX 57 9.87e-04 -0.252000 7.14e-03
REACTOME SARS COV 2 HOST INTERACTIONS 191 9.96e-04 -0.138000 7.17e-03
REACTOME CHYLOMICRON REMODELING 10 1.01e-03 0.600000 7.25e-03
REACTOME DEGRADATION OF AXIN 54 1.05e-03 -0.258000 7.47e-03
REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING 25 1.08e-03 0.377000 7.71e-03
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE 105 1.13e-03 -0.184000 7.97e-03
REACTOME REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION 84 1.14e-03 -0.205000 8.00e-03
REACTOME SARS COV 1 HOST INTERACTIONS 92 1.15e-03 -0.196000 8.05e-03
REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS 43 1.18e-03 -0.286000 8.20e-03
REACTOME GLUCAGON TYPE LIGAND RECEPTORS 32 1.18e-03 0.331000 8.20e-03
REACTOME DISEASES ASSOCIATED WITH SURFACTANT METABOLISM 9 1.18e-03 0.624000 8.20e-03
REACTOME STIMULI SENSING CHANNELS 100 1.22e-03 0.187000 8.43e-03
REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN 37 1.29e-03 -0.306000 8.86e-03
REACTOME AURKA ACTIVATION BY TPX2 69 1.31e-03 -0.224000 8.93e-03
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL 122 1.39e-03 0.168000 9.44e-03
REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE 63 1.39e-03 0.233000 9.44e-03
REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS 68 1.40e-03 -0.224000 9.46e-03
REACTOME REGULATION OF RAS BY GAPS 66 1.42e-03 -0.227000 9.53e-03
REACTOME TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS 82 1.45e-03 0.203000 9.75e-03
REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION 89 1.50e-03 -0.195000 1.00e-02
REACTOME AMINO ACIDS REGULATE MTORC1 53 1.52e-03 -0.252000 1.01e-02
REACTOME COLLAGEN CHAIN TRIMERIZATION 42 1.53e-03 0.282000 1.02e-02
REACTOME DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING 61 1.55e-03 -0.234000 1.02e-02
REACTOME CLEC7A DECTIN 1 SIGNALING 97 1.62e-03 -0.185000 1.06e-02
REACTOME PHASE 0 RAPID DEPOLARISATION 31 1.63e-03 0.327000 1.06e-02
REACTOME ORGANIC ANION TRANSPORT 5 1.63e-03 0.813000 1.06e-02
REACTOME DNA DAMAGE RECOGNITION IN GG NER 36 1.68e-03 -0.302000 1.09e-02
REACTOME INITIAL TRIGGERING OF COMPLEMENT 21 1.70e-03 0.396000 1.10e-02
REACTOME COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES 65 1.74e-03 0.225000 1.12e-02
REACTOME ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES 59 1.76e-03 0.235000 1.13e-02
REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES 101 1.76e-03 0.180000 1.13e-02
REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES 78 1.79e-03 -0.205000 1.14e-02
REACTOME SIGNALING BY PDGFR IN DISEASE 20 1.79e-03 -0.403000 1.14e-02
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX2 117 1.82e-03 -0.167000 1.15e-02
REACTOME SUMOYLATION OF DNA REPLICATION PROTEINS 46 1.88e-03 -0.265000 1.19e-02
REACTOME COPII MEDIATED VESICLE TRANSPORT 66 1.89e-03 -0.221000 1.19e-02
REACTOME NCAM1 INTERACTIONS 41 1.92e-03 0.280000 1.20e-02
REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS 60 1.95e-03 -0.231000 1.21e-02
REACTOME FGFR3 LIGAND BINDING AND ACTIVATION 12 1.95e-03 0.516000 1.21e-02
REACTOME AUTOPHAGY 144 1.96e-03 -0.149000 1.21e-02
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES 49 1.98e-03 -0.255000 1.22e-02
REACTOME REGULATION OF RUNX3 EXPRESSION AND ACTIVITY 54 2.01e-03 -0.243000 1.23e-02
REACTOME COLLAGEN DEGRADATION 61 2.07e-03 0.228000 1.26e-02
REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL 58 2.09e-03 -0.234000 1.27e-02
REACTOME G1 S SPECIFIC TRANSCRIPTION 28 2.11e-03 -0.336000 1.28e-02
REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS 14 2.29e-03 0.471000 1.38e-02
REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP 41 2.36e-03 -0.274000 1.42e-02
REACTOME CYCLIN D ASSOCIATED EVENTS IN G1 46 2.42e-03 -0.258000 1.45e-02
REACTOME DNA STRAND ELONGATION 31 2.45e-03 -0.314000 1.46e-02
REACTOME UNFOLDED PROTEIN RESPONSE UPR 88 2.48e-03 -0.187000 1.47e-02
REACTOME INTERFERON ALPHA BETA SIGNALING 70 2.62e-03 -0.208000 1.55e-02
REACTOME LAGGING STRAND SYNTHESIS 19 2.70e-03 -0.398000 1.59e-02
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING 5 2.72e-03 -0.774000 1.59e-02
REACTOME VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS 42 2.73e-03 0.267000 1.59e-02
REACTOME HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS 7 2.73e-03 0.654000 1.59e-02
REACTOME CELLULAR RESPONSE TO HYPOXIA 74 2.74e-03 -0.201000 1.59e-02
REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS 101 2.75e-03 0.172000 1.59e-02
REACTOME SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS 12 2.84e-03 -0.498000 1.64e-02
REACTOME INTERLEUKIN 36 PATHWAY 7 2.87e-03 0.651000 1.65e-02
REACTOME ION TRANSPORT BY P TYPE ATPASES 51 2.92e-03 0.241000 1.68e-02
REACTOME HIV TRANSCRIPTION INITIATION 43 2.96e-03 -0.262000 1.69e-02
REACTOME TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX 14 2.97e-03 -0.458000 1.69e-02
REACTOME G0 AND EARLY G1 27 3.00e-03 -0.330000 1.70e-02
REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES 46 3.01e-03 -0.253000 1.70e-02
REACTOME POLYMERASE SWITCHING 13 3.03e-03 -0.475000 1.71e-02
REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS 111 3.37e-03 -0.161000 1.89e-02
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX 19 3.49e-03 -0.387000 1.96e-02
REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES 353 3.55e-03 -0.090300 1.99e-02
REACTOME DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA 77 3.58e-03 -0.192000 1.99e-02
REACTOME TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES 61 3.60e-03 -0.215000 2.00e-02
REACTOME ACYL CHAIN REMODELLING OF PS 22 3.62e-03 0.358000 2.00e-02
REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES 80 3.70e-03 -0.188000 2.03e-02
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM 688 3.71e-03 -0.064900 2.03e-02
REACTOME LGI ADAM INTERACTIONS 14 3.71e-03 0.448000 2.03e-02
REACTOME TP53 REGULATES METABOLIC GENES 81 3.75e-03 -0.186000 2.05e-02
REACTOME RIPK1 MEDIATED REGULATED NECROSIS 30 3.86e-03 -0.305000 2.10e-02
REACTOME ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS 17 3.88e-03 -0.404000 2.10e-02
REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE 15 3.89e-03 -0.430000 2.10e-02
REACTOME INTERLEUKIN 1 SIGNALING 110 3.91e-03 -0.159000 2.11e-02
REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING 34 4.25e-03 -0.283000 2.28e-02
REACTOME INTERACTION BETWEEN L1 AND ANKYRINS 30 4.27e-03 0.301000 2.28e-02
REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS 63 4.33e-03 -0.208000 2.31e-02
REACTOME CHOLESTEROL BIOSYNTHESIS 25 4.43e-03 -0.329000 2.35e-02
REACTOME ACYL CHAIN REMODELLING OF PC 27 4.43e-03 0.316000 2.35e-02
REACTOME HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE 43 4.47e-03 -0.251000 2.36e-02
REACTOME SIGNALING BY KIT IN DISEASE 20 4.48e-03 -0.367000 2.36e-02
REACTOME EUKARYOTIC TRANSLATION INITIATION 110 4.60e-03 -0.156000 2.41e-02
REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES 18 4.91e-03 0.383000 2.55e-02
REACTOME PROTEIN LOCALIZATION 153 4.91e-03 -0.132000 2.55e-02
REACTOME RNA POLYMERASE I TRANSCRIPTION TERMINATION 30 4.91e-03 -0.297000 2.55e-02
REACTOME DIGESTION AND ABSORPTION 22 4.93e-03 0.346000 2.55e-02
REACTOME INTRA GOLGI TRAFFIC 43 4.98e-03 -0.247000 2.56e-02
REACTOME MAPK6 MAPK4 SIGNALING 91 4.98e-03 -0.170000 2.56e-02
REACTOME AQUAPORIN MEDIATED TRANSPORT 51 4.99e-03 0.227000 2.56e-02
REACTOME ONCOGENE INDUCED SENESCENCE 35 5.02e-03 -0.274000 2.57e-02
REACTOME FORMATION OF TC NER PRE INCISION COMPLEX 51 5.12e-03 -0.227000 2.61e-02
REACTOME SIGNALING BY WNT 318 5.15e-03 -0.091200 2.62e-02
REACTOME RAC2 GTPASE CYCLE 81 5.27e-03 -0.179000 2.67e-02
REACTOME REGULATION OF INSULIN SECRETION 77 5.28e-03 0.184000 2.67e-02
REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE 52 5.31e-03 -0.223000 2.67e-02
REACTOME PKMTS METHYLATE HISTONE LYSINES 64 5.31e-03 -0.201000 2.67e-02
REACTOME ACYL CHAIN REMODELLING OF PG 18 5.39e-03 0.379000 2.70e-02
REACTOME SIGNALING BY ERYTHROPOIETIN 25 5.48e-03 -0.321000 2.74e-02
REACTOME PLASMA LIPOPROTEIN REMODELING 33 5.73e-03 0.278000 2.85e-02
REACTOME TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS 55 5.75e-03 -0.215000 2.85e-02
REACTOME ION HOMEOSTASIS 52 5.79e-03 0.221000 2.86e-02
REACTOME FLT3 SIGNALING IN DISEASE 28 5.88e-03 -0.301000 2.90e-02
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION 29 5.89e-03 -0.295000 2.90e-02
REACTOME INTERFERON SIGNALING 193 5.92e-03 -0.115000 2.90e-02
REACTOME HIV TRANSCRIPTION ELONGATION 42 6.18e-03 -0.244000 3.02e-02
REACTOME DISEASES OF DNA REPAIR 51 6.22e-03 -0.221000 3.03e-02
REACTOME DIGESTION 17 6.28e-03 0.383000 3.05e-02
REACTOME DEFECTIVE CSF2RB CAUSES SMDP5 7 6.34e-03 0.596000 3.06e-02
REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE 5 6.35e-03 0.705000 3.06e-02
REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE 11 6.56e-03 0.473000 3.16e-02
REACTOME KSRP KHSRP BINDS AND DESTABILIZES MRNA 17 6.66e-03 -0.380000 3.19e-02
REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND 14 6.67e-03 -0.419000 3.19e-02
REACTOME NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10 12 6.70e-03 -0.452000 3.19e-02
REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX 32 6.70e-03 -0.277000 3.19e-02
REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS 18 6.73e-03 0.369000 3.19e-02
REACTOME INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS 37 6.94e-03 -0.256000 3.29e-02
REACTOME MISCELLANEOUS SUBSTRATES 12 7.09e-03 0.449000 3.35e-02
REACTOME CREATION OF C4 AND C2 ACTIVATORS 14 7.31e-03 0.414000 3.44e-02
REACTOME GABA RECEPTOR ACTIVATION 57 7.40e-03 0.205000 3.47e-02
REACTOME PYRUVATE METABOLISM 29 7.59e-03 -0.286000 3.55e-02
REACTOME HEDGEHOG LIGAND BIOGENESIS 64 7.63e-03 -0.193000 3.56e-02
REACTOME C TYPE LECTIN RECEPTORS CLRS 136 8.06e-03 -0.132000 3.75e-02
REACTOME GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION 14 8.10e-03 -0.409000 3.76e-02
REACTOME FGFR1 LIGAND BINDING AND ACTIVATION 15 8.31e-03 0.394000 3.85e-02
REACTOME RHOBTB GTPASE CYCLE 34 8.37e-03 -0.261000 3.86e-02
REACTOME INTERLEUKIN 9 SIGNALING 7 8.46e-03 -0.575000 3.89e-02
REACTOME CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2 11 8.67e-03 -0.457000 3.98e-02
REACTOME RNA POLYMERASE III TRANSCRIPTION 41 8.78e-03 -0.236000 4.02e-02
REACTOME TRNA AMINOACYLATION 40 8.85e-03 -0.239000 4.03e-02
REACTOME THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT 77 8.88e-03 -0.172000 4.04e-02
REACTOME HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR IN THE PRESENCE OF LIGAND 55 9.02e-03 -0.204000 4.09e-02
REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER 18 9.05e-03 -0.355000 4.09e-02
REACTOME ATORVASTATIN ADME 9 9.11e-03 0.502000 4.11e-02
REACTOME CONSTITUTIVE SIGNALING BY EGFRVIII 15 9.25e-03 -0.388000 4.16e-02
REACTOME INTERLEUKIN 21 SIGNALING 9 9.30e-03 -0.501000 4.17e-02
REACTOME VISUAL PHOTOTRANSDUCTION 93 9.32e-03 0.156000 4.17e-02
REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS 11 9.35e-03 0.453000 4.17e-02
REACTOME METABOLISM OF FAT SOLUBLE VITAMINS 46 9.45e-03 0.221000 4.21e-02
REACTOME SUMOYLATION OF RNA BINDING PROTEINS 47 9.51e-03 -0.219000 4.22e-02
REACTOME PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE 74 9.56e-03 0.174000 4.23e-02
REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 11 9.62e-03 -0.451000 4.25e-02
REACTOME G ALPHA Q SIGNALLING EVENTS 206 9.68e-03 0.105000 4.26e-02
REACTOME MATURATION OF SARS COV 2 NUCLEOPROTEIN 15 9.80e-03 -0.385000 4.30e-02
REACTOME DEADENYLATION OF MRNA 25 9.95e-03 -0.298000 4.36e-02
REACTOME TRIF MEDIATED PROGRAMMED CELL DEATH 9 1.01e-02 -0.495000 4.41e-02
REACTOME PLASMA LIPOPROTEIN ASSEMBLY 19 1.02e-02 0.340000 4.44e-02
REACTOME RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA 27 1.05e-02 -0.284000 4.57e-02
REACTOME PHASE 4 RESTING MEMBRANE POTENTIAL 19 1.06e-02 0.339000 4.58e-02
REACTOME PCP CE PATHWAY 91 1.06e-02 -0.155000 4.58e-02
REACTOME SARS COV 2 ACTIVATES MODULATES INNATE AND ADAPTIVE IMMUNE RESPONSES 118 1.06e-02 -0.136000 4.58e-02
REACTOME RESPIRATORY ELECTRON TRANSPORT 90 1.07e-02 -0.156000 4.60e-02
REACTOME INTERLEUKIN 15 SIGNALING 13 1.07e-02 -0.409000 4.60e-02
REACTOME CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA 63 1.08e-02 -0.186000 4.62e-02
REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS 55 1.10e-02 0.198000 4.67e-02
REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES 91 1.10e-02 -0.154000 4.67e-02
REACTOME SYNTHESIS OF GDP MANNOSE 5 1.10e-02 -0.656000 4.68e-02
REACTOME HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS 9 1.11e-02 0.489000 4.68e-02
REACTOME SUMOYLATION OF UBIQUITINYLATION PROTEINS 39 1.11e-02 -0.235000 4.68e-02
REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION 35 1.13e-02 -0.247000 4.76e-02
REACTOME TLR3 MEDIATED TICAM1 DEPENDENT PROGRAMMED CELL DEATH 6 1.14e-02 -0.596000 4.79e-02
REACTOME FGFR3B LIGAND BINDING AND ACTIVATION 7 1.15e-02 0.551000 4.82e-02
REACTOME TRANS GOLGI NETWORK VESICLE BUDDING 67 1.15e-02 -0.178000 4.82e-02
REACTOME MITOCHONDRIAL BIOGENESIS 87 1.16e-02 -0.157000 4.83e-02
REACTOME ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS 20 1.17e-02 -0.326000 4.85e-02
REACTOME SIGNALING BY EGFR IN CANCER 25 1.18e-02 -0.291000 4.90e-02
REACTOME SIGNALING BY ERBB2 ECD MUTANTS 16 1.19e-02 -0.363000 4.92e-02
REACTOME G PROTEIN ACTIVATION 24 1.21e-02 0.296000 4.97e-02
REACTOME SELENOAMINO ACID METABOLISM 108 1.21e-02 -0.140000 4.97e-02
REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS 83 1.21e-02 -0.159000 4.98e-02
REACTOME VLDL CLEARANCE 6 1.22e-02 0.591000 5.01e-02
REACTOME MISMATCH REPAIR 15 1.23e-02 -0.373000 5.03e-02
REACTOME ATTACHMENT OF GPI ANCHOR TO UPAR 7 1.29e-02 -0.543000 5.27e-02
REACTOME DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX 83 1.34e-02 -0.157000 5.43e-02
REACTOME RESOLUTION OF D LOOP STRUCTURES 33 1.36e-02 -0.248000 5.51e-02
REACTOME MRNA CAPPING 28 1.36e-02 -0.269000 5.51e-02
REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION 32 1.37e-02 0.252000 5.53e-02
REACTOME PI 3K CASCADE FGFR4 19 1.38e-02 0.326000 5.54e-02
REACTOME DNA DAMAGE BYPASS 47 1.38e-02 -0.208000 5.54e-02
REACTOME BIOLOGICAL OXIDATIONS 210 1.39e-02 0.098500 5.54e-02
REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE 19 1.39e-02 -0.326000 5.54e-02
REACTOME TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE 10 1.39e-02 0.449000 5.54e-02
REACTOME NOD1 2 SIGNALING PATHWAY 33 1.40e-02 -0.247000 5.55e-02
REACTOME TYPE I HEMIDESMOSOME ASSEMBLY 11 1.40e-02 0.428000 5.55e-02
REACTOME NUCLEAR IMPORT OF REV PROTEIN 34 1.41e-02 -0.243000 5.56e-02
REACTOME HEDGEHOG OFF STATE 111 1.41e-02 -0.135000 5.56e-02
REACTOME TRIGLYCERIDE METABOLISM 35 1.41e-02 0.240000 5.56e-02
REACTOME SHC1 EVENTS IN ERBB4 SIGNALING 14 1.42e-02 -0.378000 5.58e-02
REACTOME RAC3 GTPASE CYCLE 85 1.43e-02 -0.154000 5.60e-02
REACTOME SNRNP ASSEMBLY 53 1.49e-02 -0.193000 5.81e-02
REACTOME INTERLEUKIN 10 SIGNALING 43 1.51e-02 0.214000 5.87e-02
REACTOME MITOCHONDRIAL PROTEIN IMPORT 58 1.53e-02 -0.184000 5.96e-02
REACTOME SIGNALING BY ALK 26 1.54e-02 -0.274000 6.00e-02
REACTOME INTERLEUKIN 1 FAMILY SIGNALING 146 1.55e-02 -0.116000 6.00e-02
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER 28 1.55e-02 -0.264000 6.00e-02
REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE 11 1.58e-02 0.420000 6.10e-02
REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE 16 1.62e-02 -0.347000 6.21e-02
REACTOME SHC RELATED EVENTS TRIGGERED BY IGF1R 9 1.62e-02 -0.463000 6.22e-02
REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI 17 1.63e-02 -0.337000 6.22e-02
REACTOME INTEGRATION OF ENERGY METABOLISM 105 1.68e-02 0.135000 6.40e-02
REACTOME PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR 21 1.68e-02 -0.301000 6.40e-02
REACTOME POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION 27 1.69e-02 -0.266000 6.43e-02
REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION 20 1.69e-02 -0.308000 6.43e-02
REACTOME RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK 47 1.72e-02 -0.201000 6.51e-02
REACTOME RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX 29 1.73e-02 -0.255000 6.52e-02
REACTOME CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS 19 1.78e-02 -0.314000 6.72e-02
REACTOME SIGNALING BY FLT3 ITD AND TKD MUTANTS 16 1.79e-02 -0.342000 6.74e-02
REACTOME TRANSPORT OF FATTY ACIDS 8 1.82e-02 0.482000 6.81e-02
REACTOME HDMS DEMETHYLATE HISTONES 40 1.83e-02 -0.216000 6.84e-02
REACTOME ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION 16 1.84e-02 -0.340000 6.86e-02
REACTOME VOLTAGE GATED POTASSIUM CHANNELS 42 1.86e-02 0.210000 6.92e-02
REACTOME O LINKED GLYCOSYLATION 109 1.86e-02 0.130000 6.92e-02
REACTOME CYTOSOLIC TRNA AMINOACYLATION 22 1.87e-02 -0.290000 6.92e-02
REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH 62 1.88e-02 0.172000 6.96e-02
REACTOME RHOBTB1 GTPASE CYCLE 22 1.91e-02 -0.289000 7.04e-02
REACTOME HEDGEHOG ON STATE 85 1.93e-02 -0.147000 7.12e-02
REACTOME METABOLISM OF AMINE DERIVED HORMONES 17 1.99e-02 0.326000 7.30e-02
REACTOME TELOMERE C STRAND SYNTHESIS INITIATION 12 2.09e-02 -0.385000 7.67e-02
REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS 35 2.11e-02 -0.225000 7.72e-02
REACTOME SIGNALING BY ERBB2 IN CANCER 26 2.14e-02 -0.261000 7.82e-02
REACTOME MYD88 INDEPENDENT TLR4 CASCADE 103 2.16e-02 -0.131000 7.86e-02
REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS 33 2.16e-02 -0.231000 7.86e-02
REACTOME MRNA SPLICING MINOR PATHWAY 49 2.17e-02 -0.189000 7.88e-02
REACTOME HUR ELAVL1 BINDS AND STABILIZES MRNA 8 2.20e-02 -0.468000 7.94e-02
REACTOME EUKARYOTIC TRANSLATION ELONGATION 87 2.24e-02 -0.142000 8.09e-02
REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 22 2.27e-02 -0.281000 8.19e-02
REACTOME TNF SIGNALING 54 2.29e-02 -0.179000 8.20e-02
REACTOME REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION 9 2.29e-02 -0.438000 8.20e-02
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY 94 2.29e-02 -0.136000 8.20e-02
REACTOME PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING 11 2.30e-02 0.396000 8.22e-02
REACTOME INTEGRIN CELL SURFACE INTERACTIONS 83 2.41e-02 0.143000 8.58e-02
REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS 12 2.41e-02 0.376000 8.58e-02
REACTOME NS1 MEDIATED EFFECTS ON HOST PATHWAYS 41 2.45e-02 -0.203000 8.68e-02
REACTOME FANCONI ANEMIA PATHWAY 35 2.49e-02 -0.219000 8.81e-02
REACTOME PROCESSING OF SMDT1 16 2.50e-02 -0.324000 8.82e-02
REACTOME APOPTOTIC FACTOR MEDIATED RESPONSE 19 2.51e-02 -0.297000 8.84e-02
REACTOME SUMOYLATION OF SUMOYLATION PROTEINS 35 2.51e-02 -0.219000 8.84e-02
REACTOME COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC 52 2.57e-02 -0.179000 9.02e-02
REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS 51 2.60e-02 -0.180000 9.10e-02
REACTOME ACTIVATION OF RAS IN B CELLS 5 2.60e-02 -0.575000 9.10e-02
REACTOME GPER1 SIGNALING 45 2.69e-02 0.191000 9.39e-02
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX3 94 2.71e-02 -0.132000 9.44e-02
REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE 17 2.78e-02 -0.308000 9.65e-02
REACTOME O LINKED GLYCOSYLATION OF MUCINS 61 2.82e-02 0.162000 9.76e-02
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER 28 2.82e-02 -0.240000 9.76e-02
REACTOME INTERLEUKIN 12 SIGNALING 43 2.86e-02 -0.193000 9.85e-02
REACTOME CYTOPROTECTION BY HMOX1 59 2.86e-02 -0.165000 9.85e-02
REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX 14 2.93e-02 -0.336000 1.01e-01
REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE 10 2.96e-02 -0.397000 1.01e-01
REACTOME RUNX3 REGULATES YAP1 MEDIATED TRANSCRIPTION 8 3.02e-02 0.443000 1.03e-01
REACTOME NUCLEAR ENVELOPE NE REASSEMBLY 74 3.02e-02 -0.146000 1.03e-01
REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING 29 3.02e-02 0.232000 1.03e-01
REACTOME PERK REGULATES GENE EXPRESSION 31 3.03e-02 -0.225000 1.03e-01
REACTOME PI 3K CASCADE FGFR3 17 3.05e-02 0.303000 1.03e-01
REACTOME SIGNALING BY NTRKS 132 3.05e-02 -0.109000 1.03e-01
REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS 53 3.07e-02 -0.172000 1.04e-01
REACTOME RHOJ GTPASE CYCLE 51 3.09e-02 -0.175000 1.04e-01
REACTOME GLUTAMATE AND GLUTAMINE METABOLISM 13 3.10e-02 -0.345000 1.04e-01
REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES 39 3.10e-02 -0.200000 1.04e-01
REACTOME INTERLEUKIN 6 SIGNALING 11 3.11e-02 -0.375000 1.04e-01
REACTOME ACTIVATION OF C3 AND C5 6 3.13e-02 0.508000 1.05e-01
REACTOME MET ACTIVATES RAS SIGNALING 11 3.16e-02 -0.374000 1.05e-01
REACTOME COMPLEMENT CASCADE 54 3.16e-02 0.169000 1.05e-01
REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES 38 3.18e-02 0.201000 1.06e-01
REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE 20 3.21e-02 -0.277000 1.06e-01
REACTOME LAMININ INTERACTIONS 28 3.22e-02 0.234000 1.06e-01
REACTOME PYROPTOSIS 27 3.25e-02 -0.238000 1.07e-01
REACTOME IRON UPTAKE AND TRANSPORT 56 3.27e-02 -0.165000 1.08e-01
REACTOME RHOU GTPASE CYCLE 37 3.31e-02 -0.202000 1.09e-01
REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB 19 3.33e-02 0.282000 1.09e-01
REACTOME GAP JUNCTION ASSEMBLY 36 3.34e-02 0.205000 1.09e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS 15 3.36e-02 -0.317000 1.10e-01
REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT 99 3.41e-02 -0.123000 1.11e-01
REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS 91 3.41e-02 0.129000 1.11e-01
REACTOME REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE 81 3.43e-02 -0.136000 1.11e-01
REACTOME G ALPHA Z SIGNALLING EVENTS 48 3.43e-02 0.177000 1.11e-01
REACTOME PHASE 2 PLATEAU PHASE 14 3.45e-02 0.326000 1.11e-01
REACTOME OPIOID SIGNALLING 89 3.45e-02 0.130000 1.11e-01
REACTOME SODIUM PROTON EXCHANGERS 7 3.47e-02 0.461000 1.12e-01
REACTOME INTRINSIC PATHWAY FOR APOPTOSIS 54 3.49e-02 -0.166000 1.12e-01
REACTOME RHOBTB2 GTPASE CYCLE 22 3.54e-02 -0.259000 1.14e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH RAS 9 3.57e-02 -0.404000 1.14e-01
REACTOME FRS MEDIATED FGFR4 SIGNALING 21 3.59e-02 0.264000 1.15e-01
REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE 35 3.59e-02 -0.205000 1.15e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1 16 3.60e-02 -0.303000 1.15e-01
REACTOME LATE SARS COV 2 INFECTION EVENTS 67 3.64e-02 -0.148000 1.15e-01
REACTOME PHYSIOLOGICAL FACTORS 14 3.64e-02 0.323000 1.15e-01
REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING 30 3.64e-02 0.221000 1.15e-01
REACTOME POTENTIAL THERAPEUTICS FOR SARS 92 3.64e-02 -0.126000 1.15e-01
REACTOME CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION 24 3.67e-02 -0.246000 1.16e-01
REACTOME ERYTHROPOIETIN ACTIVATES RAS 14 3.68e-02 -0.322000 1.16e-01
REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT 31 3.75e-02 -0.216000 1.18e-01
REACTOME TRIGLYCERIDE CATABOLISM 23 3.88e-02 0.249000 1.22e-01
REACTOME DOWNSTREAM SIGNAL TRANSDUCTION 29 3.90e-02 -0.221000 1.22e-01
REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS 37 3.90e-02 -0.196000 1.22e-01
REACTOME TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS 52 3.91e-02 -0.165000 1.22e-01
REACTOME RESOLUTION OF ABASIC SITES AP SITES 38 3.93e-02 -0.193000 1.22e-01
REACTOME POLO LIKE KINASE MEDIATED EVENTS 16 3.96e-02 -0.297000 1.23e-01
REACTOME DAP12 SIGNALING 27 4.01e-02 -0.228000 1.25e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12 22 4.07e-02 0.252000 1.26e-01
REACTOME TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT 18 4.11e-02 -0.278000 1.27e-01
REACTOME GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER 25 4.21e-02 -0.235000 1.30e-01
REACTOME GENERATION OF SECOND MESSENGER MOLECULES 30 4.24e-02 0.214000 1.31e-01
REACTOME CALNEXIN CALRETICULIN CYCLE 26 4.25e-02 -0.230000 1.31e-01
REACTOME RHOV GTPASE CYCLE 36 4.26e-02 -0.195000 1.31e-01
REACTOME CARGO CONCENTRATION IN THE ER 32 4.29e-02 -0.207000 1.31e-01
REACTOME GLUCOCORTICOID BIOSYNTHESIS 10 4.30e-02 0.370000 1.31e-01
REACTOME PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS 21 4.31e-02 0.255000 1.32e-01
REACTOME ATTACHMENT AND ENTRY 16 4.32e-02 0.292000 1.32e-01
REACTOME RECYCLING OF EIF2 GDP 7 4.33e-02 -0.441000 1.32e-01
REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION 8 4.34e-02 0.412000 1.32e-01
REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY 25 4.34e-02 -0.233000 1.32e-01
REACTOME MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS 13 4.36e-02 -0.323000 1.32e-01
REACTOME COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC 98 4.36e-02 -0.118000 1.32e-01
REACTOME DNA REPLICATION INITIATION 7 4.37e-02 -0.440000 1.32e-01
REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS 9 4.41e-02 0.387000 1.33e-01
REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL 41 4.42e-02 -0.182000 1.33e-01
REACTOME SYNTHESIS OF DIPHTHAMIDE EEF2 8 4.44e-02 -0.410000 1.33e-01
REACTOME VIRAL MESSENGER RNA SYNTHESIS 44 4.46e-02 -0.175000 1.33e-01
REACTOME SIGNALING BY INTERLEUKINS 444 4.49e-02 -0.055500 1.34e-01
REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS 66 4.52e-02 0.143000 1.35e-01
REACTOME TCR SIGNALING 113 4.56e-02 -0.109000 1.36e-01
REACTOME TNFR2 NON CANONICAL NF KB PATHWAY 96 4.61e-02 -0.118000 1.37e-01
REACTOME CRISTAE FORMATION 27 4.62e-02 -0.222000 1.37e-01
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S 53 4.65e-02 -0.158000 1.37e-01
REACTOME MET ACTIVATES PI3K AKT SIGNALING 6 4.68e-02 -0.469000 1.38e-01
REACTOME SIGNALING BY CSF3 G CSF 30 4.72e-02 -0.209000 1.39e-01
REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION 13 4.73e-02 -0.318000 1.39e-01
REACTOME FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS 8 4.76e-02 -0.404000 1.40e-01
REACTOME RHO GTPASE CYCLE 423 4.77e-02 -0.056100 1.40e-01
REACTOME FREE FATTY ACID RECEPTORS 5 4.96e-02 0.507000 1.45e-01
REACTOME NECTIN NECL TRANS HETERODIMERIZATION 7 4.99e-02 0.428000 1.46e-01
REACTOME SIGNALING BY FGFR4 IN DISEASE 11 5.01e-02 -0.341000 1.46e-01
REACTOME CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND 16 5.09e-02 -0.282000 1.48e-01
REACTOME TIGHT JUNCTION INTERACTIONS 29 5.11e-02 0.209000 1.48e-01
REACTOME RRNA MODIFICATION IN THE MITOCHONDRION 6 5.12e-02 -0.460000 1.48e-01
REACTOME TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE 39 5.13e-02 -0.180000 1.48e-01
REACTOME TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA 36 5.14e-02 -0.188000 1.48e-01
REACTOME CYTOCHROME C MEDIATED APOPTOTIC RESPONSE 12 5.15e-02 -0.325000 1.48e-01
REACTOME GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION 42 5.15e-02 0.174000 1.48e-01
REACTOME ENOS ACTIVATION 11 5.21e-02 0.338000 1.50e-01
REACTOME STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES 16 5.22e-02 -0.280000 1.50e-01
REACTOME RAB REGULATION OF TRAFFICKING 110 5.26e-02 -0.107000 1.51e-01
REACTOME LIPID PARTICLE ORGANIZATION 6 5.27e-02 0.457000 1.51e-01
REACTOME SIGNALING BY MST1 5 5.30e-02 0.500000 1.51e-01
REACTOME ASPIRIN ADME 42 5.34e-02 0.172000 1.52e-01
REACTOME G ALPHA 12 13 SIGNALLING EVENTS 74 5.34e-02 0.130000 1.52e-01
REACTOME TRANSCRIPTIONAL REGULATION BY VENTX 41 5.36e-02 -0.174000 1.52e-01
REACTOME RRNA PROCESSING IN THE MITOCHONDRION 9 5.38e-02 -0.371000 1.52e-01
REACTOME TOLL LIKE RECEPTOR 9 TLR9 CASCADE 100 5.38e-02 -0.112000 1.52e-01
REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY 15 5.39e-02 -0.287000 1.52e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL 14 5.42e-02 -0.297000 1.53e-01
REACTOME IRS ACTIVATION 5 5.42e-02 0.497000 1.53e-01
REACTOME INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE 20 5.45e-02 -0.248000 1.53e-01
REACTOME SIGNALING BY HEDGEHOG 148 5.46e-02 -0.091500 1.53e-01
REACTOME SIGNALING BY LRP5 MUTANTS 6 5.46e-02 0.453000 1.53e-01
REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION 42 5.49e-02 0.171000 1.54e-01
REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION 59 5.52e-02 -0.144000 1.54e-01
REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS 21 5.63e-02 0.241000 1.57e-01
REACTOME TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA 17 5.64e-02 -0.267000 1.57e-01
REACTOME CHOLINE CATABOLISM 6 5.64e-02 0.450000 1.57e-01
REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION 160 5.69e-02 -0.087200 1.58e-01
REACTOME CELL JUNCTION ORGANIZATION 89 5.70e-02 0.117000 1.58e-01
REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY 46 5.71e-02 -0.162000 1.58e-01
REACTOME ESTABLISHMENT OF SISTER CHROMATID COHESION 9 5.72e-02 -0.366000 1.58e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN 21 5.76e-02 -0.239000 1.58e-01
REACTOME INTERLEUKIN 12 FAMILY SIGNALING 53 5.78e-02 -0.151000 1.58e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH RAS 8 5.78e-02 -0.387000 1.58e-01
REACTOME HDL REMODELING 10 5.80e-02 0.346000 1.58e-01
REACTOME FGFR2 LIGAND BINDING AND ACTIVATION 19 5.80e-02 0.251000 1.58e-01
REACTOME RELAXIN RECEPTORS 8 5.80e-02 0.387000 1.58e-01
REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX 31 5.81e-02 -0.197000 1.58e-01
REACTOME TIE2 SIGNALING 18 5.85e-02 -0.258000 1.59e-01
REACTOME SHC1 EVENTS IN EGFR SIGNALING 14 5.87e-02 -0.292000 1.60e-01
REACTOME METABOLISM OF FOLATE AND PTERINES 17 5.89e-02 -0.265000 1.60e-01
REACTOME DIGESTION OF DIETARY CARBOHYDRATE 6 5.90e-02 0.445000 1.60e-01
REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX 21 5.92e-02 0.238000 1.60e-01
REACTOME NEGATIVE REGULATION OF MAPK PATHWAY 41 5.93e-02 -0.170000 1.60e-01
REACTOME VLDL ASSEMBLY 5 6.00e-02 0.486000 1.62e-01
REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR 19 6.01e-02 0.249000 1.62e-01
REACTOME SENSORY PERCEPTION OF TASTE 47 6.06e-02 0.158000 1.63e-01
REACTOME BUDDING AND MATURATION OF HIV VIRION 28 6.07e-02 -0.205000 1.63e-01
REACTOME FORMATION OF APOPTOSOME 10 6.08e-02 -0.342000 1.63e-01
REACTOME METALLOTHIONEINS BIND METALS 11 6.10e-02 0.326000 1.63e-01
REACTOME DEFECTIVE RIPK1 MEDIATED REGULATED NECROSIS 7 6.11e-02 -0.409000 1.63e-01
REACTOME TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS 43 6.15e-02 -0.165000 1.63e-01
REACTOME PINK1 PRKN MEDIATED MITOPHAGY 22 6.15e-02 -0.230000 1.63e-01
REACTOME DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS 19 6.15e-02 -0.248000 1.63e-01
REACTOME NUCLEAR ENVELOPE BREAKDOWN 52 6.16e-02 -0.150000 1.63e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2 17 6.17e-02 0.262000 1.63e-01
REACTOME MET ACTIVATES PTK2 SIGNALING 30 6.20e-02 0.197000 1.64e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS 8 6.21e-02 0.381000 1.64e-01
REACTOME BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA 17 6.26e-02 -0.261000 1.65e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS 15 6.27e-02 0.278000 1.65e-01
REACTOME IRF3 MEDIATED INDUCTION OF TYPE I IFN 13 6.30e-02 -0.298000 1.66e-01
REACTOME MITOTIC TELOPHASE CYTOKINESIS 11 6.33e-02 -0.323000 1.66e-01
REACTOME TRANSPORT OF ORGANIC ANIONS 10 6.33e-02 0.339000 1.66e-01
REACTOME FCERI MEDIATED CA 2 MOBILIZATION 30 6.34e-02 -0.196000 1.66e-01
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY 33 6.44e-02 -0.186000 1.68e-01
REACTOME GAP JUNCTION TRAFFICKING AND REGULATION 49 6.45e-02 0.153000 1.68e-01
REACTOME INTERLEUKIN 2 FAMILY SIGNALING 40 6.50e-02 -0.169000 1.69e-01
REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION 36 6.54e-02 -0.177000 1.70e-01
REACTOME SYNTHESIS OF PG 8 6.56e-02 -0.376000 1.70e-01
REACTOME PROTEIN METHYLATION 17 6.62e-02 -0.257000 1.71e-01
REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING 28 6.84e-02 0.199000 1.77e-01
REACTOME SERINE BIOSYNTHESIS 9 6.84e-02 -0.351000 1.77e-01
REACTOME FCERI MEDIATED MAPK ACTIVATION 32 6.88e-02 -0.186000 1.77e-01
REACTOME ABC TRANSPORTER DISORDERS 76 6.88e-02 -0.121000 1.77e-01
REACTOME REGULATION OF MECP2 EXPRESSION AND ACTIVITY 30 6.98e-02 -0.191000 1.79e-01
REACTOME SIGNALING BY EGFR 49 7.12e-02 -0.149000 1.83e-01
REACTOME REGULATION OF PTEN GENE TRANSCRIPTION 59 7.16e-02 -0.136000 1.84e-01
REACTOME PI3K EVENTS IN ERBB4 SIGNALING 10 7.24e-02 -0.328000 1.85e-01
REACTOME ACYL CHAIN REMODELLING OF PE 29 7.28e-02 0.192000 1.86e-01
REACTOME COHESIN LOADING ONTO CHROMATIN 8 7.35e-02 -0.365000 1.87e-01
REACTOME FRS MEDIATED FGFR3 SIGNALING 19 7.36e-02 0.237000 1.87e-01
REACTOME CHYLOMICRON ASSEMBLY 10 7.36e-02 0.327000 1.87e-01
REACTOME FATTY ACYL COA BIOSYNTHESIS 36 7.55e-02 -0.171000 1.92e-01
REACTOME PENTOSE PHOSPHATE PATHWAY 12 7.65e-02 -0.295000 1.94e-01
REACTOME CA DEPENDENT EVENTS 36 7.66e-02 0.171000 1.94e-01
REACTOME DEFECTIVE LFNG CAUSES SCDO3 5 7.77e-02 0.456000 1.96e-01
REACTOME SIGNALING BY NTRK3 TRKC 17 7.86e-02 -0.246000 1.98e-01
REACTOME TACHYKININ RECEPTORS BIND TACHYKININS 5 7.89e-02 0.454000 1.99e-01
REACTOME ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE 9 7.92e-02 0.338000 1.99e-01
REACTOME CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY 25 7.98e-02 -0.202000 2.00e-01
REACTOME ALK MUTANTS BIND TKIS 12 8.08e-02 -0.291000 2.03e-01
REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE 15 8.19e-02 -0.259000 2.05e-01
REACTOME TRANSLESION SYNTHESIS BY POLH 19 8.22e-02 -0.230000 2.05e-01
REACTOME METABOLISM OF STEROIDS 150 8.26e-02 -0.082100 2.06e-01
REACTOME RUNX3 REGULATES WNT SIGNALING 8 8.35e-02 0.353000 2.08e-01
REACTOME METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES 33 8.36e-02 0.174000 2.08e-01
REACTOME PI METABOLISM 79 8.42e-02 -0.112000 2.09e-01
REACTOME BETA CATENIN INDEPENDENT WNT SIGNALING 145 8.43e-02 -0.083000 2.09e-01
REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER 49 8.47e-02 -0.142000 2.09e-01
REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 44 8.47e-02 -0.150000 2.09e-01
REACTOME DNA DAMAGE REVERSAL 8 8.51e-02 -0.352000 2.10e-01
REACTOME MITOPHAGY 28 8.52e-02 -0.188000 2.10e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH CDC42 19 8.53e-02 0.228000 2.10e-01
REACTOME HDR THROUGH MMEJ ALT NHEJ 12 8.56e-02 -0.287000 2.10e-01
REACTOME FOLDING OF ACTIN BY CCT TRIC 10 8.57e-02 -0.314000 2.10e-01
REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS 23 8.59e-02 0.207000 2.10e-01
REACTOME RORA ACTIVATES GENE EXPRESSION 17 8.61e-02 -0.240000 2.10e-01
REACTOME PROTEIN REPAIR 6 8.63e-02 -0.404000 2.10e-01
REACTOME SIGNALING BY SCF KIT 42 8.63e-02 -0.153000 2.10e-01
REACTOME METABOLISM OF LIPIDS 709 8.63e-02 -0.037800 2.10e-01
REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS 8 8.72e-02 0.349000 2.12e-01
REACTOME SIGNALING BY FGFR IN DISEASE 62 8.77e-02 -0.125000 2.13e-01
REACTOME CIRCADIAN CLOCK 68 8.79e-02 -0.120000 2.13e-01
REACTOME INTRAFLAGELLAR TRANSPORT 50 8.81e-02 -0.139000 2.13e-01
REACTOME CALCITONIN LIKE LIGAND RECEPTORS 10 8.88e-02 0.311000 2.14e-01
REACTOME SIGNALING BY NOTCH1 T 7 9 NOTCH1 M1580 K2555 TRANSLOCATION MUTANT 7 8.90e-02 0.371000 2.14e-01
REACTOME MITOCHONDRIAL TRNA AMINOACYLATION 20 8.90e-02 -0.220000 2.14e-01
REACTOME TERMINATION OF TRANSLESION DNA SYNTHESIS 32 8.91e-02 -0.174000 2.14e-01
REACTOME ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS 27 8.94e-02 -0.189000 2.15e-01
REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX 15 8.95e-02 -0.253000 2.15e-01
REACTOME INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES 28 8.98e-02 -0.185000 2.15e-01
REACTOME RHOF GTPASE CYCLE 40 9.05e-02 -0.155000 2.16e-01
REACTOME PLATELET HOMEOSTASIS 85 9.05e-02 0.106000 2.16e-01
REACTOME CELLULAR HEXOSE TRANSPORT 21 9.11e-02 0.213000 2.18e-01
REACTOME EPITHELIAL MESENCHYMAL TRANSITION EMT DURING GASTRULATION 7 9.14e-02 0.368000 2.18e-01
REACTOME NUCLEAR PORE COMPLEX NPC DISASSEMBLY 36 9.15e-02 -0.163000 2.18e-01
REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS 29 9.19e-02 0.181000 2.18e-01
REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY 10 9.21e-02 0.308000 2.18e-01
REACTOME SHC MEDIATED CASCADE FGFR4 19 9.21e-02 0.223000 2.18e-01
REACTOME SYNDECAN INTERACTIONS 26 9.22e-02 0.191000 2.18e-01
REACTOME REGULATION OF SIGNALING BY CBL 22 9.23e-02 -0.207000 2.18e-01
REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES 27 9.28e-02 -0.187000 2.19e-01
REACTOME MITOCHONDRIAL CALCIUM ION TRANSPORT 23 9.32e-02 -0.202000 2.20e-01
REACTOME RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION 8 9.38e-02 -0.342000 2.21e-01
REACTOME ACTIVATION OF TRKA RECEPTORS 6 9.41e-02 0.395000 2.21e-01
REACTOME FORMATION OF AXIAL MESODERM 14 9.45e-02 0.258000 2.22e-01
REACTOME CD28 CO STIMULATION 32 9.53e-02 -0.170000 2.23e-01
REACTOME RND3 GTPASE CYCLE 41 9.56e-02 -0.150000 2.24e-01
REACTOME INACTIVATION OF CSF3 G CSF SIGNALING 25 9.61e-02 -0.192000 2.24e-01
REACTOME REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS 15 9.62e-02 -0.248000 2.24e-01
REACTOME BINDING OF TCF LEF CTNNB1 TO TARGET GENE PROMOTERS 8 9.74e-02 0.338000 2.27e-01
REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING 45 9.74e-02 -0.143000 2.27e-01
REACTOME SENSORY PERCEPTION OF SALTY TASTE 6 9.78e-02 0.390000 2.27e-01
REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI 26 9.79e-02 -0.188000 2.27e-01
REACTOME SUPPRESSION OF APOPTOSIS 7 9.84e-02 -0.361000 2.28e-01
REACTOME PARASITE INFECTION 57 9.93e-02 -0.126000 2.29e-01
REACTOME TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX 10 9.94e-02 -0.301000 2.29e-01
REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS 299 9.94e-02 -0.055400 2.29e-01
REACTOME NUCLEOTIDE BIOSYNTHESIS 14 9.95e-02 -0.254000 2.29e-01
REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES 37 1.00e-01 0.156000 2.31e-01
REACTOME DEFECTIVE EXT2 CAUSES EXOSTOSES 2 12 1.01e-01 0.273000 2.32e-01
REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA 28 1.01e-01 -0.179000 2.32e-01
REACTOME IRE1ALPHA ACTIVATES CHAPERONES 48 1.02e-01 -0.136000 2.34e-01
REACTOME MICRORNA MIRNA BIOGENESIS 25 1.03e-01 -0.189000 2.34e-01
REACTOME DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE 17 1.03e-01 0.229000 2.34e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1 25 1.03e-01 0.189000 2.34e-01
REACTOME LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME 11 1.04e-01 -0.283000 2.38e-01
REACTOME RET SIGNALING 40 1.06e-01 0.148000 2.41e-01
REACTOME NGF STIMULATED TRANSCRIPTION 38 1.07e-01 -0.151000 2.43e-01
REACTOME ACTIVATION OF CASPASES THROUGH APOPTOSOME MEDIATED CLEAVAGE 5 1.08e-01 -0.415000 2.45e-01
REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR 24 1.09e-01 0.189000 2.46e-01
REACTOME PKA ACTIVATION IN GLUCAGON SIGNALLING 17 1.09e-01 0.225000 2.46e-01
REACTOME G2 PHASE 5 1.09e-01 -0.414000 2.46e-01
REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS 5 1.09e-01 0.414000 2.46e-01
REACTOME ETHANOL OXIDATION 12 1.09e-01 -0.267000 2.46e-01
REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM 23 1.09e-01 -0.193000 2.46e-01
REACTOME RETINOID CYCLE DISEASE EVENTS 11 1.10e-01 0.278000 2.47e-01
REACTOME RHOG GTPASE CYCLE 71 1.10e-01 -0.110000 2.47e-01
REACTOME SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER 54 1.10e-01 -0.126000 2.47e-01
REACTOME ARACHIDONATE PRODUCTION FROM DAG 5 1.11e-01 0.412000 2.48e-01
REACTOME PI 3K CASCADE FGFR1 21 1.11e-01 0.201000 2.48e-01
REACTOME FGFR2 ALTERNATIVE SPLICING 27 1.11e-01 -0.177000 2.48e-01
REACTOME LYSOSOME VESICLE BIOGENESIS 33 1.12e-01 -0.160000 2.48e-01
REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS 21 1.12e-01 -0.200000 2.49e-01
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION 81 1.13e-01 -0.102000 2.51e-01
REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY 14 1.14e-01 0.244000 2.53e-01
REACTOME NRCAM INTERACTIONS 6 1.15e-01 0.371000 2.55e-01
REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS 16 1.16e-01 0.227000 2.57e-01
REACTOME GRB7 EVENTS IN ERBB2 SIGNALING 5 1.17e-01 0.405000 2.57e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH METHYLATION 19 1.17e-01 -0.208000 2.57e-01
REACTOME RNA POLYMERASE III CHAIN ELONGATION 18 1.17e-01 -0.214000 2.57e-01
REACTOME STAT3 NUCLEAR EVENTS DOWNSTREAM OF ALK SIGNALING 9 1.18e-01 -0.301000 2.59e-01
REACTOME REACTIONS SPECIFIC TO THE COMPLEX N GLYCAN SYNTHESIS PATHWAY 10 1.20e-01 -0.284000 2.65e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS 9 1.21e-01 -0.298000 2.65e-01
REACTOME XENOBIOTICS 22 1.21e-01 0.191000 2.65e-01
REACTOME REGULATION OF SIGNALING BY NODAL 9 1.21e-01 0.298000 2.66e-01
REACTOME TRANSPORT OF NUCLEOTIDE SUGARS 8 1.22e-01 -0.316000 2.67e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX 91 1.22e-01 -0.093700 2.67e-01
REACTOME RHO GTPASES ACTIVATE WASPS AND WAVES 34 1.23e-01 -0.153000 2.68e-01
REACTOME LYSOSPHINGOLIPID AND LPA RECEPTORS 14 1.24e-01 0.238000 2.68e-01
REACTOME HISTIDINE CATABOLISM 8 1.24e-01 0.314000 2.68e-01
REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING 16 1.24e-01 -0.222000 2.68e-01
REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES 7 1.24e-01 -0.336000 2.68e-01
REACTOME SUMOYLATION OF DNA METHYLATION PROTEINS 16 1.25e-01 -0.222000 2.70e-01
REACTOME INFECTION WITH MYCOBACTERIUM TUBERCULOSIS 25 1.25e-01 -0.177000 2.70e-01
REACTOME REGULATION OF NPAS4 MRNA TRANSLATION 9 1.25e-01 -0.295000 2.70e-01
REACTOME DAP12 INTERACTIONS 37 1.25e-01 -0.146000 2.70e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH PI3K 7 1.25e-01 -0.335000 2.70e-01
REACTOME CONDENSATION OF PROMETAPHASE CHROMOSOMES 11 1.26e-01 -0.267000 2.70e-01
REACTOME RND2 GTPASE CYCLE 42 1.26e-01 -0.137000 2.70e-01
REACTOME REGULATION OF RUNX1 EXPRESSION AND ACTIVITY 17 1.28e-01 -0.213000 2.75e-01
REACTOME RAS PROCESSING 22 1.29e-01 -0.187000 2.76e-01
REACTOME TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY 30 1.29e-01 -0.160000 2.76e-01
REACTOME FASL CD95L SIGNALING 5 1.29e-01 -0.392000 2.76e-01
REACTOME ELASTIC FIBRE FORMATION 44 1.29e-01 0.132000 2.76e-01
REACTOME REGULATION OF BACH1 ACTIVITY 11 1.30e-01 -0.263000 2.78e-01
REACTOME SELECTIVE AUTOPHAGY 79 1.31e-01 -0.098400 2.78e-01
REACTOME RND1 GTPASE CYCLE 41 1.31e-01 -0.136000 2.78e-01
REACTOME CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE 49 1.31e-01 -0.125000 2.78e-01
REACTOME EGFR DOWNREGULATION 30 1.31e-01 -0.159000 2.78e-01
REACTOME DISEASES OF MISMATCH REPAIR MMR 5 1.33e-01 -0.388000 2.82e-01
REACTOME ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT 23 1.33e-01 -0.181000 2.82e-01
REACTOME TRANSCRIPTIONAL REGULATION BY MECP2 60 1.33e-01 -0.112000 2.82e-01
REACTOME DAG AND IP3 SIGNALING 40 1.34e-01 0.137000 2.82e-01
REACTOME TRAIL SIGNALING 8 1.34e-01 -0.306000 2.82e-01
REACTOMEMATURATION OF SARS COV 1 NUCLEOPROTEIN 11 1.34e-01 -0.261000 2.82e-01
REACTOME RESPONSE OF MTB TO PHAGOCYTOSIS 22 1.36e-01 -0.184000 2.86e-01
REACTOME MATURATION OF SARS COV 2 SPIKE PROTEIN 35 1.36e-01 -0.145000 2.86e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION TERMINATION 23 1.37e-01 -0.179000 2.87e-01
REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A 26 1.38e-01 -0.168000 2.88e-01
REACTOME METHIONINE SALVAGE PATHWAY 6 1.38e-01 -0.350000 2.89e-01
REACTOME P75NTR REGULATES AXONOGENESIS 9 1.38e-01 0.285000 2.89e-01
REACTOME ACTIVATION OF RAC1 12 1.39e-01 -0.247000 2.90e-01
REACTOME FGFRL1 MODULATION OF FGFR1 SIGNALING 13 1.39e-01 0.237000 2.90e-01
REACTOME MHC CLASS II ANTIGEN PRESENTATION 121 1.39e-01 -0.077800 2.90e-01
REACTOME CREATINE METABOLISM 9 1.39e-01 0.284000 2.90e-01
REACTOME CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION 11 1.40e-01 -0.257000 2.91e-01
REACTOME MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS 7 1.41e-01 -0.322000 2.92e-01
REACTOME L1CAM INTERACTIONS 112 1.42e-01 0.080300 2.94e-01
REACTOME SMOOTH MUSCLE CONTRACTION 43 1.43e-01 0.129000 2.95e-01
REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK 17 1.43e-01 -0.205000 2.95e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST 14 1.43e-01 -0.226000 2.95e-01
REACTOME HIV ELONGATION ARREST AND RECOVERY 33 1.44e-01 -0.147000 2.96e-01
REACTOME GLUCURONIDATION 23 1.44e-01 0.176000 2.96e-01
REACTOME OTHER SEMAPHORIN INTERACTIONS 18 1.44e-01 0.199000 2.96e-01
REACTOME CELL CELL COMMUNICATION 126 1.45e-01 0.075200 2.97e-01
REACTOME SARS COV 1 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS 16 1.45e-01 -0.210000 2.98e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA 25 1.46e-01 0.168000 2.98e-01
REACTOME CELLULAR RESPONSE TO HEAT STRESS 99 1.46e-01 -0.084600 2.98e-01
REACTOME GRB2 EVENTS IN ERBB2 SIGNALING 16 1.46e-01 -0.210000 2.98e-01
REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION 19 1.46e-01 0.192000 2.99e-01
REACTOME REGULATION OF GENE EXPRESSION IN ENDOCRINE COMMITTED NEUROG3 PROGENITOR CELLS 5 1.47e-01 0.375000 2.99e-01
REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ 6 1.47e-01 -0.342000 2.99e-01
REACTOME HYALURONAN METABOLISM 17 1.47e-01 0.203000 3.00e-01
REACTOME ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS 41 1.48e-01 0.130000 3.01e-01
REACTOME NGF INDEPENDANT TRKA ACTIVATION 5 1.49e-01 0.373000 3.02e-01
REACTOME ERYTHROPOIETIN ACTIVATES STAT5 7 1.49e-01 -0.315000 3.02e-01
REACTOME HYDROLYSIS OF LPC 9 1.50e-01 0.277000 3.02e-01
REACTOME REPRESSION OF WNT TARGET GENES 14 1.50e-01 0.222000 3.03e-01
REACTOME ANTIMICROBIAL PEPTIDES 76 1.50e-01 0.095500 3.03e-01
REACTOME MUSCARINIC ACETYLCHOLINE RECEPTORS 5 1.50e-01 0.372000 3.03e-01
REACTOME NETRIN MEDIATED REPULSION SIGNALS 8 1.51e-01 0.293000 3.03e-01
REACTOME OVARIAN TUMOR DOMAIN PROTEASES 36 1.51e-01 -0.138000 3.03e-01
REACTOME TRANSPORT AND SYNTHESIS OF PAPS 6 1.53e-01 -0.337000 3.07e-01
REACTOME REGULATION OF PTEN MRNA TRANSLATION 9 1.55e-01 -0.274000 3.10e-01
REACTOME ALPHA DEFENSINS 6 1.55e-01 0.335000 3.10e-01
REACTOME FLT3 SIGNALING 38 1.56e-01 -0.133000 3.11e-01
REACTOME TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS 26 1.56e-01 0.161000 3.11e-01
REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING 32 1.56e-01 0.145000 3.11e-01
REACTOME CITRIC ACID CYCLE TCA CYCLE 21 1.56e-01 -0.179000 3.11e-01
REACTOME ER QUALITY CONTROL COMPARTMENT ERQC 21 1.57e-01 -0.178000 3.13e-01
REACTOME SIGNALING BY ERBB2 50 1.58e-01 -0.116000 3.13e-01
REACTOME SYNAPTIC ADHESION LIKE MOLECULES 19 1.58e-01 0.187000 3.14e-01
REACTOME RECYCLING OF BILE ACIDS AND SALTS 18 1.59e-01 0.192000 3.14e-01
REACTOME RUNX3 REGULATES P14 ARF 10 1.59e-01 -0.257000 3.14e-01
REACTOME PROCESSING OF INTRONLESS PRE MRNAS 19 1.59e-01 -0.187000 3.14e-01
REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE 22 1.59e-01 0.173000 3.14e-01
REACTOME MET ACTIVATES RAP1 AND RAC1 11 1.60e-01 -0.245000 3.15e-01
REACTOME PASSIVE TRANSPORT BY AQUAPORINS 13 1.60e-01 0.225000 3.16e-01
REACTOME CA2 ACTIVATED K CHANNELS 9 1.60e-01 0.270000 3.16e-01
REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER 77 1.61e-01 0.092400 3.16e-01
REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK 111 1.61e-01 0.076900 3.17e-01
REACTOME INTERLEUKIN 17 SIGNALING 66 1.62e-01 -0.099600 3.17e-01
REACTOME DEATH RECEPTOR SIGNALING 143 1.62e-01 -0.067800 3.17e-01
REACTOME FBXW7 MUTANTS AND NOTCH1 IN CANCER 5 1.63e-01 -0.360000 3.19e-01
REACTOME G PROTEIN MEDIATED EVENTS 53 1.63e-01 0.111000 3.19e-01
REACTOME PREGNENOLONE BIOSYNTHESIS 12 1.63e-01 -0.232000 3.19e-01
REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX 8 1.64e-01 -0.284000 3.19e-01
REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN 32 1.66e-01 -0.142000 3.23e-01
REACTOME REGULATION OF FZD BY UBIQUITINATION 21 1.66e-01 0.175000 3.23e-01
REACTOME MINERALOCORTICOID BIOSYNTHESIS 6 1.66e-01 0.326000 3.23e-01
REACTOME RHOT1 GTPASE CYCLE 5 1.67e-01 -0.357000 3.23e-01
REACTOME COMPLEX I BIOGENESIS 49 1.67e-01 -0.114000 3.23e-01
REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES 14 1.67e-01 -0.213000 3.23e-01
REACTOME SIGNALING BY CSF1 M CSF IN MYELOID CELLS 30 1.68e-01 -0.145000 3.25e-01
REACTOME FATTY ACID METABOLISM 170 1.68e-01 -0.061200 3.25e-01
REACTOME VEGF LIGAND RECEPTOR INTERACTIONS 7 1.69e-01 0.300000 3.26e-01
REACTOME REDUCTION OF CYTOSOLIC CA LEVELS 11 1.71e-01 0.238000 3.30e-01
REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS 5 1.71e-01 0.353000 3.30e-01
REACTOME CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN 45 1.72e-01 0.118000 3.30e-01
REACTOME SUMOYLATION OF TRANSCRIPTION FACTORS 20 1.72e-01 -0.176000 3.31e-01
REACTOME CARNITINE METABOLISM 13 1.72e-01 -0.219000 3.31e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST 18 1.73e-01 -0.185000 3.32e-01
REACTOME LOSS OF FUNCTION OF SMAD2 3 IN CANCER 7 1.73e-01 -0.297000 3.32e-01
REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS 81 1.75e-01 -0.087200 3.34e-01
REACTOME ACTIVATION OF MATRIX METALLOPROTEINASES 30 1.77e-01 0.142000 3.37e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES 11 1.77e-01 -0.235000 3.37e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES 29 1.78e-01 0.145000 3.38e-01
REACTOME ACYL CHAIN REMODELING OF CL 5 1.78e-01 -0.348000 3.38e-01
REACTOME SIGNALING BY NTRK2 TRKB 25 1.79e-01 -0.155000 3.40e-01
REACTOME ORGANIC ANION TRANSPORTERS 10 1.80e-01 0.245000 3.41e-01
REACTOME MET PROMOTES CELL MOTILITY 41 1.80e-01 0.121000 3.41e-01
REACTOME SHC MEDIATED CASCADE FGFR3 17 1.80e-01 0.188000 3.41e-01
REACTOME ANCHORING FIBRIL FORMATION 13 1.80e-01 0.215000 3.41e-01
REACTOME TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS 29 1.81e-01 -0.143000 3.43e-01
REACTOME METABOLISM OF NUCLEOTIDES 94 1.82e-01 -0.079600 3.44e-01
REACTOME REGULATION OF NPAS4 GENE EXPRESSION 13 1.83e-01 -0.214000 3.44e-01
REACTOME INTEGRATION OF PROVIRUS 9 1.83e-01 -0.256000 3.44e-01
REACTOME TRAF6 MEDIATED NF KB ACTIVATION 24 1.84e-01 -0.157000 3.45e-01
REACTOME TRIGLYCERIDE BIOSYNTHESIS 12 1.84e-01 0.221000 3.46e-01
REACTOME TBC RABGAPS 40 1.85e-01 -0.121000 3.47e-01
REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF 17 1.86e-01 -0.185000 3.48e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES 12 1.86e-01 -0.221000 3.48e-01
REACTOME SODIUM CALCIUM EXCHANGERS 11 1.86e-01 0.230000 3.48e-01
REACTOME APOPTOTIC EXECUTION PHASE 49 1.87e-01 -0.109000 3.49e-01
REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT 15 1.87e-01 0.197000 3.49e-01
REACTOME CD209 DC SIGN SIGNALING 20 1.89e-01 -0.170000 3.51e-01
REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE 48 1.89e-01 -0.110000 3.51e-01
REACTOME CREB PHOSPHORYLATION 6 1.89e-01 -0.310000 3.51e-01
REACTOME AMINO ACID CONJUGATION 9 1.90e-01 0.252000 3.52e-01
REACTOME JOSEPHIN DOMAIN DUBS 11 1.91e-01 -0.228000 3.54e-01
REACTOME TNFR1 INDUCED PROAPOPTOTIC SIGNALING 23 1.91e-01 -0.157000 3.54e-01
REACTOME DECTIN 2 FAMILY 26 1.92e-01 0.148000 3.54e-01
REACTOME PTK6 PROMOTES HIF1A STABILIZATION 6 1.92e-01 0.307000 3.54e-01
REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION 74 1.92e-01 0.087700 3.54e-01
REACTOME CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT 19 1.92e-01 -0.173000 3.54e-01
REACTOME TRP CHANNELS 27 1.92e-01 0.145000 3.54e-01
REACTOME REGULATION BY C FLIP 11 1.93e-01 -0.227000 3.54e-01
REACTOME RHO GTPASES ACTIVATE NADPH OXIDASES 21 1.93e-01 -0.164000 3.54e-01
REACTOME RHOD GTPASE CYCLE 49 1.93e-01 -0.107000 3.54e-01
REACTOME PHOSPHORYLATION OF THE APC C 20 1.93e-01 -0.168000 3.54e-01
REACTOME SODIUM COUPLED PHOSPHATE COTRANSPORTERS 5 1.96e-01 0.334000 3.59e-01
REACTOME DEFECTIVE GALNT3 CAUSES HFTC 16 1.96e-01 0.187000 3.59e-01
REACTOME FRS MEDIATED FGFR1 SIGNALING 23 1.97e-01 0.155000 3.61e-01
REACTOME SOS MEDIATED SIGNALLING 7 1.98e-01 -0.281000 3.61e-01
REACTOME SIGNAL AMPLIFICATION 33 1.98e-01 0.130000 3.61e-01
REACTOME SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER 15 1.98e-01 0.192000 3.61e-01
REACTOME TELOMERE EXTENSION BY TELOMERASE 22 1.99e-01 -0.158000 3.62e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES 10 2.00e-01 -0.234000 3.63e-01
REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION 23 2.01e-01 0.154000 3.64e-01
REACTOME COBALAMIN CBL METABOLISM 7 2.01e-01 -0.279000 3.64e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE 11 2.02e-01 0.222000 3.67e-01
REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION 20 2.03e-01 -0.165000 3.67e-01
REACTOME INSULIN RECEPTOR RECYCLING 29 2.03e-01 -0.136000 3.67e-01
REACTOME N GLYCAN ANTENNAE ELONGATION 15 2.04e-01 -0.190000 3.67e-01
REACTOME ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING 23 2.04e-01 -0.153000 3.67e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1 20 2.04e-01 0.164000 3.67e-01
REACTOME MIRO GTPASE CYCLE 8 2.05e-01 -0.259000 3.68e-01
REACTOME SIGNALING BY FGFR1 IN DISEASE 38 2.05e-01 -0.119000 3.68e-01
REACTOME THYROXINE BIOSYNTHESIS 10 2.05e-01 0.232000 3.68e-01
REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION 15 2.05e-01 0.189000 3.68e-01
REACTOME CGMP EFFECTS 16 2.06e-01 0.183000 3.69e-01
REACTOME RUNX3 REGULATES NOTCH SIGNALING 13 2.07e-01 -0.202000 3.70e-01
REACTOME MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION 15 2.08e-01 -0.188000 3.72e-01
REACTOME MYOCLONIC EPILEPSY OF LAFORA 9 2.08e-01 0.242000 3.72e-01
REACTOME GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION 7 2.09e-01 0.275000 3.72e-01
REACTOME PLASMA LIPOPROTEIN CLEARANCE 37 2.09e-01 0.119000 3.72e-01
REACTOME GASTRULATION 49 2.09e-01 0.104000 3.73e-01
REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING 30 2.10e-01 -0.132000 3.73e-01
REACTOME EARLY PHASE OF HIV LIFE CYCLE 14 2.10e-01 -0.194000 3.73e-01
REACTOME ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS 24 2.11e-01 -0.148000 3.74e-01
REACTOME NRAGE SIGNALS DEATH THROUGH JNK 53 2.11e-01 0.099300 3.74e-01
REACTOME NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 19 2.12e-01 -0.166000 3.75e-01
REACTOME ENDOGENOUS STEROLS 26 2.12e-01 0.141000 3.75e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES 16 2.13e-01 -0.180000 3.77e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K 12 2.15e-01 -0.207000 3.79e-01
REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES 77 2.16e-01 0.081600 3.80e-01
REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS 11 2.16e-01 -0.216000 3.80e-01
REACTOME SLC TRANSPORTER DISORDERS 94 2.17e-01 0.073700 3.82e-01
REACTOME SIGNALING BY FGFR2 72 2.19e-01 -0.083700 3.85e-01
REACTOME MAPK FAMILY SIGNALING CASCADES 314 2.19e-01 -0.040300 3.85e-01
REACTOME REGULATION OF IFNG SIGNALING 14 2.20e-01 -0.189000 3.87e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3 11 2.24e-01 -0.212000 3.93e-01
REACTOME MAPK1 ERK2 ACTIVATION 9 2.26e-01 -0.233000 3.95e-01
REACTOME NUCLEOTIDE SALVAGE 21 2.26e-01 -0.152000 3.96e-01
REACTOME SYNTHESIS OF PA 38 2.27e-01 0.113000 3.96e-01
REACTOME HEME SIGNALING 47 2.27e-01 -0.102000 3.96e-01
REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION 12 2.28e-01 0.201000 3.97e-01
REACTOME LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX 5 2.28e-01 -0.311000 3.97e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION 27 2.29e-01 -0.134000 3.98e-01
REACTOME RAF ACTIVATION 33 2.30e-01 -0.121000 3.99e-01
REACTOME STAT5 ACTIVATION 7 2.31e-01 -0.261000 4.01e-01
REACTOME RHOC GTPASE CYCLE 71 2.33e-01 -0.081900 4.04e-01
REACTOME METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION 15 2.34e-01 0.178000 4.04e-01
REACTOME CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER 25 2.34e-01 -0.138000 4.05e-01
REACTOME MET RECEPTOR RECYCLING 10 2.35e-01 -0.217000 4.06e-01
REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS 118 2.38e-01 0.062800 4.11e-01
REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS 38 2.39e-01 -0.110000 4.11e-01
REACTOME LATE ENDOSOMAL MICROAUTOPHAGY 33 2.39e-01 -0.118000 4.11e-01
REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS 32 2.39e-01 0.120000 4.11e-01
REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON 17 2.40e-01 -0.164000 4.13e-01
REACTOME SIGNALING BY VEGF 102 2.41e-01 -0.067200 4.13e-01
REACTOME CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY 12 2.41e-01 -0.195000 4.13e-01
REACTOME TERMINAL PATHWAY OF COMPLEMENT 8 2.41e-01 -0.239000 4.14e-01
REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY 51 2.42e-01 0.094700 4.14e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION 36 2.43e-01 -0.112000 4.16e-01
REACTOME DISEASES OF METABOLISM 237 2.45e-01 0.043900 4.18e-01
REACTOME BASIGIN INTERACTIONS 24 2.45e-01 0.137000 4.19e-01
REACTOME PEPTIDE HORMONE METABOLISM 84 2.47e-01 0.073100 4.20e-01
REACTOME SIGNALING BY ERBB4 57 2.47e-01 -0.088700 4.20e-01
REACTOME NEPHRIN FAMILY INTERACTIONS 22 2.47e-01 -0.142000 4.21e-01
REACTOME AMINE LIGAND BINDING RECEPTORS 40 2.48e-01 0.106000 4.21e-01
REACTOME ASSEMBLY OF THE HIV VIRION 16 2.48e-01 -0.167000 4.21e-01
REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS 9 2.50e-01 0.221000 4.24e-01
REACTOME RELEASE OF HH NP FROM THE SECRETING CELL 8 2.51e-01 0.234000 4.25e-01
REACTOME BICARBONATE TRANSPORTERS 10 2.51e-01 0.210000 4.25e-01
REACTOME RHOBTB3 ATPASE CYCLE 8 2.52e-01 -0.234000 4.26e-01
REACTOME CHYLOMICRON CLEARANCE 5 2.53e-01 0.295000 4.27e-01
REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE 30 2.54e-01 0.120000 4.29e-01
REACTOME BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA 5 2.58e-01 -0.292000 4.34e-01
REACTOME RHO GTPASES ACTIVATE CIT 19 2.58e-01 -0.150000 4.34e-01
REACTOME MATURATION OF SARS COV 1 SPIKE PROTEIN 5 2.58e-01 -0.292000 4.34e-01
REACTOME DISSOLUTION OF FIBRIN CLOT 13 2.59e-01 -0.181000 4.35e-01
REACTOME SHC1 EVENTS IN ERBB2 SIGNALING 22 2.59e-01 -0.139000 4.35e-01
REACTOME REGULATION OF TP53 EXPRESSION AND DEGRADATION 37 2.60e-01 -0.107000 4.36e-01
REACTOME ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS 20 2.60e-01 -0.145000 4.36e-01
REACTOME TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7 12 2.63e-01 -0.187000 4.40e-01
REACTOME G PROTEIN BETA GAMMA SIGNALLING 30 2.66e-01 0.117000 4.45e-01
REACTOME HYALURONAN BIOSYNTHESIS AND EXPORT 5 2.66e-01 0.287000 4.45e-01
REACTOME CLATHRIN MEDIATED ENDOCYTOSIS 139 2.68e-01 -0.054500 4.46e-01
REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS 11 2.68e-01 -0.193000 4.46e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX IN CANCER 8 2.68e-01 -0.226000 4.47e-01
REACTOME RSK ACTIVATION 5 2.69e-01 -0.286000 4.47e-01
REACTOME SYNTHESIS OF PE 13 2.69e-01 -0.177000 4.47e-01
REACTOME DEFECTS IN VITAMIN AND COFACTOR METABOLISM 21 2.69e-01 -0.139000 4.47e-01
REACTOME PHASE 3 RAPID REPOLARISATION 8 2.70e-01 0.225000 4.48e-01
REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B 24 2.72e-01 -0.130000 4.50e-01
REACTOME TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION 5 2.72e-01 -0.284000 4.50e-01
REACTOME EGFR TRANSACTIVATION BY GASTRIN 9 2.72e-01 -0.211000 4.50e-01
REACTOME DOWNREGULATION OF ERBB4 SIGNALING 9 2.73e-01 -0.211000 4.50e-01
REACTOME SIGNALING BY NOTCH1 69 2.74e-01 -0.076200 4.51e-01
REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM 20 2.74e-01 -0.141000 4.51e-01
REACTOME UNWINDING OF DNA 12 2.74e-01 -0.182000 4.52e-01
REACTOME GROWTH HORMONE RECEPTOR SIGNALING 24 2.79e-01 -0.128000 4.58e-01
REACTOME REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA 15 2.80e-01 -0.161000 4.61e-01
REACTOME MUCOPOLYSACCHARIDOSES 10 2.82e-01 -0.197000 4.63e-01
REACTOME SIGNALING BY LEPTIN 11 2.82e-01 -0.187000 4.63e-01
REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS 11 2.83e-01 0.187000 4.64e-01
REACTOME THE PHOTOTRANSDUCTION CASCADE 32 2.83e-01 0.110000 4.64e-01
REACTOME SUMO IS PROTEOLYTICALLY PROCESSED 6 2.84e-01 -0.253000 4.64e-01
REACTOME PHENYLALANINE AND TYROSINE METABOLISM 11 2.84e-01 -0.187000 4.64e-01
REACTOME DEFECTIVE CHST3 CAUSES SEDCJD 7 2.85e-01 0.234000 4.64e-01
REACTOME SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS 16 2.85e-01 0.154000 4.65e-01
REACTOME ARACHIDONIC ACID METABOLISM 57 2.85e-01 0.081800 4.65e-01
REACTOME HS GAG BIOSYNTHESIS 28 2.86e-01 0.117000 4.65e-01
REACTOME LONG TERM POTENTIATION 22 2.88e-01 0.131000 4.68e-01
REACTOME RHO GTPASES ACTIVATE PAKS 19 2.88e-01 -0.141000 4.68e-01
REACTOME TYROSINE CATABOLISM 5 2.89e-01 -0.274000 4.69e-01
REACTOME RHOH GTPASE CYCLE 37 2.91e-01 -0.100000 4.72e-01
REACTOME RESPONSE TO METAL IONS 14 2.93e-01 0.162000 4.75e-01
REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL 129 2.94e-01 0.053500 4.76e-01
REACTOME ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM 12 2.95e-01 -0.174000 4.78e-01
REACTOME DRUG ADME 103 2.99e-01 0.059300 4.82e-01
REACTOME SCAVENGING BY CLASS F RECEPTORS 6 2.99e-01 -0.245000 4.83e-01
REACTOME DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS 25 3.00e-01 -0.120000 4.83e-01
REACTOME ERK MAPK TARGETS 20 3.00e-01 -0.134000 4.83e-01
REACTOME MTORC1 MEDIATED SIGNALLING 23 3.00e-01 -0.125000 4.83e-01
REACTOME SENSING OF DNA DOUBLE STRAND BREAKS 6 3.01e-01 -0.244000 4.83e-01
REACTOME TRYPTOPHAN CATABOLISM 14 3.01e-01 -0.160000 4.83e-01
REACTOME SMALL INTERFERING RNA SIRNA BIOGENESIS 9 3.04e-01 -0.198000 4.87e-01
REACTOME SUMOYLATION OF INTRACELLULAR RECEPTORS 29 3.05e-01 -0.110000 4.88e-01
REACTOME INTERLEUKIN RECEPTOR SHC SIGNALING 24 3.05e-01 -0.121000 4.89e-01
REACTOME CRMPS IN SEMA3A SIGNALING 15 3.06e-01 0.153000 4.89e-01
REACTOME RHOQ GTPASE CYCLE 57 3.07e-01 -0.078300 4.89e-01
REACTOME PECAM1 INTERACTIONS 12 3.07e-01 0.170000 4.89e-01
REACTOME RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION 6 3.09e-01 -0.240000 4.92e-01
REACTOME REGULATION OF PTEN LOCALIZATION 8 3.09e-01 -0.208000 4.92e-01
REACTOME DEFECTS IN COBALAMIN B12 METABOLISM 13 3.09e-01 -0.163000 4.92e-01
REACTOME ADRENOCEPTORS 9 3.10e-01 0.195000 4.92e-01
REACTOME RHO GTPASES ACTIVATE ROCKS 19 3.10e-01 -0.135000 4.92e-01
REACTOME ADHERENS JUNCTIONS INTERACTIONS 33 3.11e-01 -0.102000 4.93e-01
REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE 109 3.12e-01 -0.056100 4.94e-01
REACTOME FRUCTOSE METABOLISM 7 3.13e-01 0.220000 4.95e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES 8 3.13e-01 -0.206000 4.95e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2 13 3.13e-01 -0.162000 4.95e-01
REACTOME TOLL LIKE RECEPTOR CASCADES 158 3.14e-01 -0.046400 4.96e-01
REACTOME HYALURONAN UPTAKE AND DEGRADATION 12 3.14e-01 0.168000 4.96e-01
REACTOME MTOR SIGNALLING 40 3.16e-01 -0.091600 4.98e-01
REACTOME INTERLEUKIN 1 PROCESSING 9 3.17e-01 -0.193000 4.98e-01
REACTOME PI 3K CASCADE FGFR2 22 3.19e-01 0.123000 5.02e-01
REACTOME GDP FUCOSE BIOSYNTHESIS 6 3.19e-01 0.235000 5.02e-01
REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS 13 3.20e-01 0.159000 5.02e-01
REACTOME CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS 100 3.21e-01 -0.057500 5.03e-01
REACTOME UPTAKE OF DIETARY COBALAMINS INTO ENTEROCYTES 9 3.21e-01 0.191000 5.03e-01
REACTOME TRANSPORT OF RCBL WITHIN THE BODY 8 3.23e-01 -0.202000 5.06e-01
REACTOME PEXOPHAGY 11 3.24e-01 -0.172000 5.06e-01
REACTOME HORMONE LIGAND BINDING RECEPTORS 12 3.24e-01 -0.164000 5.07e-01
REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN 76 3.25e-01 -0.065300 5.07e-01
REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION 23 3.26e-01 0.118000 5.08e-01
REACTOME SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS 14 3.26e-01 -0.151000 5.09e-01
REACTOME WAX AND PLASMALOGEN BIOSYNTHESIS 5 3.27e-01 -0.253000 5.09e-01
REACTOME SIALIC ACID METABOLISM 33 3.28e-01 0.098500 5.09e-01
REACTOME METABOLISM OF PORPHYRINS 26 3.28e-01 0.111000 5.10e-01
REACTOME O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS 38 3.29e-01 0.091400 5.11e-01
REACTOME TRANSLESION SYNTHESIS BY POLK 17 3.30e-01 -0.136000 5.12e-01
REACTOME INDUCTION OF CELL CELL FUSION 12 3.33e-01 0.161000 5.16e-01
REACTOME HSF1 DEPENDENT TRANSACTIVATION 37 3.34e-01 0.091800 5.16e-01
REACTOME ONCOGENIC MAPK SIGNALING 79 3.34e-01 -0.062900 5.16e-01
REACTOME VITAMINS 6 3.34e-01 0.228000 5.17e-01
REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES 29 3.37e-01 -0.103000 5.21e-01
REACTOME COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING 32 3.40e-01 -0.097400 5.25e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS 5 3.41e-01 -0.246000 5.25e-01
REACTOME PROPIONYL COA CATABOLISM 5 3.41e-01 -0.246000 5.25e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR4 26 3.41e-01 0.108000 5.25e-01
REACTOME RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS 9 3.41e-01 0.183000 5.25e-01
REACTOME GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION 30 3.43e-01 -0.100000 5.26e-01
REACTOME RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES 16 3.43e-01 0.137000 5.26e-01
REACTOME ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN 13 3.44e-01 0.152000 5.26e-01
REACTOME PI3K EVENTS IN ERBB2 SIGNALING 16 3.45e-01 -0.136000 5.27e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL 15 3.46e-01 0.141000 5.28e-01
REACTOME LRR FLII INTERACTING PROTEIN 1 LRRFIP1 ACTIVATES TYPE I IFN PRODUCTION 5 3.46e-01 -0.243000 5.29e-01
REACTOME CALCINEURIN ACTIVATES NFAT 9 3.47e-01 -0.181000 5.29e-01
REACTOME CROSSLINKING OF COLLAGEN FIBRILS 16 3.47e-01 0.136000 5.29e-01
REACTOME SARS COV 2 MODULATES AUTOPHAGY 11 3.47e-01 -0.164000 5.29e-01
REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING 33 3.48e-01 0.094500 5.29e-01
REACTOME PI5P REGULATES TP53 ACETYLATION 9 3.48e-01 -0.180000 5.30e-01
REACTOME N GLYCAN TRIMMING AND ELONGATION IN THE CIS GOLGI 5 3.49e-01 -0.242000 5.30e-01
REACTOME ACYL CHAIN REMODELING OF DAG AND TAG 5 3.49e-01 0.242000 5.30e-01
REACTOME NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION 20 3.50e-01 0.121000 5.30e-01
REACTOME MET RECEPTOR ACTIVATION 6 3.52e-01 0.220000 5.32e-01
REACTOME SULFIDE OXIDATION TO SULFATE 6 3.52e-01 -0.219000 5.32e-01
REACTOME FIBRONECTIN MATRIX FORMATION 6 3.52e-01 -0.219000 5.33e-01
REACTOME MAP2K AND MAPK ACTIVATION 38 3.53e-01 -0.087000 5.34e-01
REACTOME SIGNALING BY PTK6 54 3.54e-01 -0.073000 5.34e-01
REACTOME SCAVENGING OF HEME FROM PLASMA 13 3.54e-01 0.149000 5.34e-01
REACTOME ROLE OF ABL IN ROBO SLIT SIGNALING 8 3.55e-01 -0.189000 5.34e-01
REACTOME RAS SIGNALING DOWNSTREAM OF NF1 LOSS OF FUNCTION VARIANTS 7 3.55e-01 -0.202000 5.34e-01
REACTOME RHOB GTPASE CYCLE 67 3.56e-01 -0.065200 5.36e-01
REACTOME REGULATION OF NF KAPPA B SIGNALING 17 3.58e-01 -0.129000 5.38e-01
REACTOME GLUCONEOGENESIS 33 3.58e-01 -0.092400 5.38e-01
REACTOME ALPHA OXIDATION OF PHYTANATE 6 3.62e-01 -0.215000 5.43e-01
REACTOME INACTIVATION OF CDC42 AND RAC1 8 3.64e-01 -0.185000 5.46e-01
REACTOME PURINE SALVAGE 12 3.67e-01 -0.150000 5.49e-01
REACTOME STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS 10 3.67e-01 -0.165000 5.49e-01
REACTOME TRNA MODIFICATION IN THE MITOCHONDRION 8 3.68e-01 -0.184000 5.49e-01
REACTOME SYNTHESIS OF LIPOXINS LX 6 3.70e-01 0.211000 5.52e-01
REACTOME NOTCH HLH TRANSCRIPTION PATHWAY 24 3.71e-01 -0.105000 5.54e-01
REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS 23 3.72e-01 0.108000 5.54e-01
REACTOME NUCLEOTIDE CATABOLISM 35 3.73e-01 0.086900 5.56e-01
REACTOME GLYCOGEN METABOLISM 22 3.74e-01 0.110000 5.56e-01
REACTOME NONCANONICAL ACTIVATION OF NOTCH3 8 3.75e-01 -0.181000 5.57e-01
REACTOME FATTY ACIDS BOUND TO GPR40 FFAR1 REGULATE INSULIN SECRETION 8 3.76e-01 0.181000 5.58e-01
REACTOME CELL CELL JUNCTION ORGANIZATION 64 3.76e-01 0.063900 5.58e-01
REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS 23 3.77e-01 -0.107000 5.58e-01
REACTOME BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA 5 3.78e-01 -0.228000 5.59e-01
REACTOME FRUCTOSE CATABOLISM 5 3.78e-01 0.228000 5.60e-01
REACTOME MODULATION BY MTB OF HOST IMMUNE SYSTEM 6 3.80e-01 -0.207000 5.62e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL 14 3.81e-01 0.135000 5.62e-01
REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC 26 3.81e-01 -0.099300 5.62e-01
REACTOME CAMK IV MEDIATED PHOSPHORYLATION OF CREB 10 3.82e-01 0.160000 5.62e-01
REACTOME WNT MEDIATED ACTIVATION OF DVL 8 3.83e-01 -0.178000 5.64e-01
REACTOME CD163 MEDIATING AN ANTI INFLAMMATORY RESPONSE 9 3.83e-01 -0.168000 5.64e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES 43 3.84e-01 -0.076700 5.65e-01
REACTOME GLYCOGEN SYNTHESIS 13 3.85e-01 0.139000 5.66e-01
REACTOME SIGNAL TRANSDUCTION BY L1 20 3.86e-01 0.112000 5.66e-01
REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX 9 3.88e-01 -0.166000 5.69e-01
REACTOME SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS 43 3.90e-01 -0.075700 5.71e-01
REACTOME INTESTINAL ABSORPTION 5 3.91e-01 0.221000 5.72e-01
REACTOME SIGNALING BY PDGF 57 3.93e-01 -0.065400 5.74e-01
REACTOME NFE2L2 REGULATING ANTI OXIDANT DETOXIFICATION ENZYMES 17 3.93e-01 -0.120000 5.74e-01
REACTOME SHC MEDIATED CASCADE FGFR1 21 3.93e-01 0.108000 5.74e-01
REACTOME LINOLEIC ACID LA METABOLISM 7 3.94e-01 -0.186000 5.75e-01
REACTOME OLFACTORY SIGNALING PATHWAY 348 3.95e-01 0.026600 5.75e-01
REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK 28 3.97e-01 -0.092600 5.77e-01
REACTOME INITIATION OF NUCLEAR ENVELOPE NE REFORMATION 18 3.98e-01 -0.115000 5.79e-01
REACTOME GLUCOSE METABOLISM 90 4.02e-01 -0.051100 5.84e-01
REACTOME EPH EPHRIN SIGNALING 90 4.02e-01 -0.051100 5.84e-01
REACTOME ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS 87 4.03e-01 0.051900 5.85e-01
REACTOME UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION 19 4.04e-01 0.111000 5.85e-01
REACTOME VEGFR2 MEDIATED CELL PROLIFERATION 19 4.04e-01 -0.111000 5.85e-01
REACTOME DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A 5 4.06e-01 0.215000 5.88e-01
REACTOME SIGNALLING TO ERKS 34 4.08e-01 -0.082100 5.89e-01
REACTOME SIGNALING BY RECEPTOR TYROSINE KINASES 507 4.09e-01 -0.021400 5.90e-01
REACTOME TYSND1 CLEAVES PEROXISOMAL PROTEINS 7 4.10e-01 -0.180000 5.91e-01
REACTOME SYNTHESIS OF DOLICHYL PHOSPHATE 6 4.11e-01 -0.194000 5.93e-01
REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS 28 4.12e-01 -0.089700 5.93e-01
REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION 9 4.13e-01 -0.158000 5.94e-01
REACTOME SIGNALING BY NODAL 20 4.17e-01 0.105000 5.99e-01
REACTOME CD28 DEPENDENT PI3K AKT SIGNALING 22 4.17e-01 -0.099900 5.99e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS 6 4.19e-01 -0.190000 6.02e-01
REACTOME KILLING MECHANISMS 11 4.22e-01 -0.140000 6.05e-01
REACTOME THE NLRP3 INFLAMMASOME 16 4.23e-01 -0.116000 6.06e-01
REACTOME RUNX3 REGULATES BCL2L11 BIM TRANSCRIPTION 5 4.23e-01 -0.207000 6.06e-01
REACTOME ANDROGEN BIOSYNTHESIS 11 4.26e-01 0.139000 6.09e-01
REACTOME DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15 8 4.27e-01 0.162000 6.10e-01
REACTOME RIP MEDIATED NFKB ACTIVATION VIA ZBP1 16 4.28e-01 -0.114000 6.11e-01
REACTOME OTHER INTERLEUKIN SIGNALING 24 4.28e-01 0.093400 6.11e-01
REACTOME INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL 14 4.29e-01 -0.122000 6.11e-01
REACTOME CHONDROITIN SULFATE BIOSYNTHESIS 18 4.30e-01 -0.107000 6.12e-01
REACTOME METABOLISM OF CARBOHYDRATES 279 4.30e-01 -0.027400 6.12e-01
REACTOME EARLY SARS COV 2 INFECTION EVENTS 34 4.30e-01 -0.078100 6.12e-01
REACTOME BILE ACID AND BILE SALT METABOLISM 45 4.31e-01 0.067800 6.12e-01
REACTOME POLB DEPENDENT LONG PATCH BASE EXCISION REPAIR 8 4.31e-01 -0.161000 6.12e-01
REACTOME P2Y RECEPTORS 9 4.34e-01 0.151000 6.15e-01
REACTOME METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS 122 4.35e-01 -0.040900 6.16e-01
REACTOME SUMO IS CONJUGATED TO E1 UBA2 SAE1 5 4.35e-01 -0.202000 6.16e-01
REACTOME SUPPRESSION OF PHAGOSOMAL MATURATION 13 4.40e-01 -0.124000 6.22e-01
REACTOME ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY 5 4.41e-01 0.199000 6.23e-01
REACTOME RIBAVIRIN ADME 11 4.41e-01 -0.134000 6.23e-01
REACTOME POST TRANSCRIPTIONAL SILENCING BY SMALL RNAS 7 4.43e-01 -0.167000 6.25e-01
REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY 5 4.44e-01 -0.198000 6.26e-01
REACTOME DEFECTIVE CHST6 CAUSES MCDC1 8 4.45e-01 0.156000 6.26e-01
REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS 6 4.48e-01 0.179000 6.29e-01
REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS 16 4.48e-01 0.110000 6.29e-01
REACTOME GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION 34 4.48e-01 -0.075200 6.29e-01
REACTOME NEF MEDIATED CD8 DOWN REGULATION 7 4.48e-01 -0.166000 6.29e-01
REACTOME MAPK3 ERK1 ACTIVATION 10 4.50e-01 -0.138000 6.30e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1 31 4.51e-01 0.078300 6.31e-01
REACTOME VASOPRESSIN LIKE RECEPTORS 5 4.51e-01 -0.195000 6.31e-01
REACTOME ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS 11 4.52e-01 -0.131000 6.32e-01
REACTOME LTC4 CYSLTR MEDIATED IL4 PRODUCTION 6 4.52e-01 0.177000 6.32e-01
REACTOME NEUREXINS AND NEUROLIGINS 51 4.54e-01 0.060600 6.34e-01
REACTOME DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1 9 4.55e-01 -0.144000 6.35e-01
REACTOME COENZYME A BIOSYNTHESIS 8 4.56e-01 -0.152000 6.36e-01
REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS 15 4.61e-01 0.110000 6.41e-01
REACTOME ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS 7 4.61e-01 -0.161000 6.42e-01
REACTOME INTERLEUKIN 6 FAMILY SIGNALING 24 4.62e-01 -0.086800 6.42e-01
REACTOME SIGNALING BY TGFB FAMILY MEMBERS 119 4.63e-01 -0.038900 6.43e-01
REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV 1 INFECTION 5 4.64e-01 -0.189000 6.44e-01
REACTOME PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING 5 4.65e-01 0.189000 6.45e-01
REACTOME FCGR3A MEDIATED IL10 SYNTHESIS 36 4.67e-01 0.070000 6.48e-01
REACTOME MRNA EDITING C TO U CONVERSION 8 4.68e-01 0.148000 6.48e-01
REACTOME FRS MEDIATED FGFR2 SIGNALING 24 4.68e-01 0.085500 6.48e-01
REACTOME VLDLR INTERNALISATION AND DEGRADATION 16 4.70e-01 -0.104000 6.49e-01
REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX 39 4.70e-01 -0.066800 6.49e-01
REACTOME INTERLEUKIN 27 SIGNALING 11 4.74e-01 -0.125000 6.54e-01
REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS 16 4.76e-01 -0.103000 6.56e-01
REACTOME IRAK4 DEFICIENCY TLR2 4 17 4.76e-01 -0.099800 6.56e-01
REACTOME PIWI INTERACTING RNA PIRNA BIOGENESIS 29 4.78e-01 -0.076100 6.58e-01
REACTOME EPHRIN SIGNALING 17 4.80e-01 0.099100 6.59e-01
REACTOME DISEASES OF BASE EXCISION REPAIR 5 4.80e-01 0.182000 6.60e-01
REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS 16 4.81e-01 -0.102000 6.60e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS 11 4.81e-01 -0.123000 6.60e-01
REACTOME ACTIVATION OF BH3 ONLY PROTEINS 30 4.82e-01 -0.074100 6.61e-01
REACTOME CLEC7A INFLAMMASOME PATHWAY 6 4.83e-01 -0.166000 6.61e-01
REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS 63 4.83e-01 -0.051100 6.61e-01
REACTOME PHASE 1 INACTIVATION OF FAST NA CHANNELS 6 4.85e-01 0.165000 6.63e-01
REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION 9 4.86e-01 -0.134000 6.64e-01
REACTOME DEGRADATION OF CYSTEINE AND HOMOCYSTEINE 15 4.87e-01 -0.104000 6.65e-01
REACTOME COSTIMULATION BY THE CD28 FAMILY 64 4.89e-01 0.050000 6.66e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING 5 4.89e-01 -0.179000 6.66e-01
REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN 15 4.91e-01 -0.103000 6.68e-01
REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION 31 4.92e-01 -0.071300 6.69e-01
REACTOME RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION 22 4.93e-01 -0.084400 6.70e-01
REACTOME REGULATION OF BETA CELL DEVELOPMENT 41 4.94e-01 0.061700 6.71e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING 6 4.96e-01 -0.161000 6.73e-01
REACTOME RHO GTPASES ACTIVATE KTN1 11 4.96e-01 -0.119000 6.73e-01
REACTOME SIGNALING BY BMP 27 4.97e-01 0.075600 6.73e-01
REACTOME GP1B IX V ACTIVATION SIGNALLING 11 4.97e-01 -0.118000 6.73e-01
REACTOME HDL ASSEMBLY 8 4.99e-01 0.138000 6.75e-01
REACTOME CYP2E1 REACTIONS 10 5.02e-01 0.123000 6.78e-01
REACTOME HEME DEGRADATION 15 5.02e-01 0.100000 6.78e-01
REACTOME AGGREPHAGY 42 5.05e-01 -0.059500 6.81e-01
REACTOME BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA 6 5.06e-01 -0.157000 6.82e-01
REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III 31 5.07e-01 -0.068900 6.83e-01
REACTOME SIGNALING BY FGFR2 IN DISEASE 42 5.08e-01 -0.059100 6.83e-01
REACTOME DEFENSINS 33 5.08e-01 0.066500 6.83e-01
REACTOME BIOTIN TRANSPORT AND METABOLISM 10 5.09e-01 -0.121000 6.84e-01
REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION 26 5.10e-01 -0.074600 6.85e-01
REACTOME EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION 27 5.12e-01 0.072900 6.87e-01
REACTOME MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS 17 5.13e-01 -0.091600 6.87e-01
REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY 26 5.13e-01 -0.074100 6.87e-01
REACTOME DRUG MEDIATED INHIBITION OF CDK4 CDK6 ACTIVITY 5 5.14e-01 -0.169000 6.87e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM 38 5.17e-01 0.060800 6.91e-01
REACTOME SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL 8 5.18e-01 -0.132000 6.92e-01
REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS 6 5.18e-01 -0.152000 6.92e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL 24 5.19e-01 0.076000 6.92e-01
REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE 20 5.19e-01 -0.083200 6.92e-01
REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES 34 5.22e-01 -0.063500 6.95e-01
REACTOME ENDOSOMAL VACUOLAR PATHWAY 11 5.23e-01 -0.111000 6.95e-01
REACTOME PARACETAMOL ADME 26 5.24e-01 0.072200 6.97e-01
REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION 11 5.26e-01 0.111000 6.98e-01
REACTOME DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE 30 5.26e-01 -0.066900 6.98e-01
REACTOME AZATHIOPRINE ADME 22 5.26e-01 -0.078100 6.98e-01
REACTOME SIGNALING BY FGFR2 IIIA TM 19 5.27e-01 -0.083800 6.99e-01
REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING 6 5.28e-01 0.149000 6.99e-01
REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY 29 5.29e-01 -0.067500 7.00e-01
REACTOME FLT3 SIGNALING THROUGH SRC FAMILY KINASES 6 5.31e-01 0.148000 7.02e-01
REACTOME RETROGRADE NEUROTROPHIN SIGNALLING 14 5.32e-01 -0.096400 7.02e-01
REACTOME MYOGENESIS 29 5.32e-01 -0.067000 7.02e-01
REACTOME SMAC XIAP REGULATED APOPTOTIC RESPONSE 7 5.32e-01 -0.136000 7.02e-01
REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS 17 5.34e-01 0.087000 7.03e-01
REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET 8 5.35e-01 -0.127000 7.03e-01
REACTOME DOPAMINE RECEPTORS 5 5.35e-01 0.160000 7.03e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR3 24 5.35e-01 0.073100 7.04e-01
REACTOME GLYCOGEN STORAGE DISEASES 15 5.36e-01 0.092300 7.04e-01
REACTOME GLYCOLYSIS 70 5.36e-01 -0.042700 7.04e-01
REACTOME DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS 14 5.39e-01 0.094900 7.06e-01
REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND 21 5.39e-01 0.077400 7.06e-01
REACTOME ORGANIC CATION TRANSPORT 10 5.40e-01 -0.112000 7.08e-01
REACTOME MOLYBDENUM COFACTOR BIOSYNTHESIS 6 5.41e-01 -0.144000 7.08e-01
REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS 27 5.41e-01 -0.067900 7.08e-01
REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS 46 5.42e-01 -0.052000 7.08e-01
REACTOME SYNTHESIS OF PI 5 5.45e-01 0.156000 7.11e-01
REACTOME SYNTHESIS OF UDP N ACETYL GLUCOSAMINE 7 5.45e-01 -0.132000 7.11e-01
REACTOME BETA OXIDATION OF PRISTANOYL COA 9 5.46e-01 -0.116000 7.11e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS 9 5.48e-01 0.116000 7.13e-01
REACTOME FREE FATTY ACIDS REGULATE INSULIN SECRETION 10 5.49e-01 0.110000 7.14e-01
REACTOME ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY 10 5.50e-01 -0.109000 7.15e-01
REACTOME SYNTHESIS OF 12 EICOSATETRAENOIC ACID DERIVATIVES 7 5.51e-01 -0.130000 7.16e-01
REACTOME PEPTIDE HORMONE BIOSYNTHESIS 13 5.51e-01 0.095400 7.16e-01
REACTOME SIGNALING BY NOTCH2 32 5.52e-01 -0.060800 7.16e-01
REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION 32 5.52e-01 0.060700 7.16e-01
REACTOME DOWNREGULATION OF ERBB2 SIGNALING 29 5.56e-01 -0.063200 7.19e-01
REACTOME KETONE BODY METABOLISM 9 5.58e-01 -0.113000 7.21e-01
REACTOME METABOLISM OF COFACTORS 19 5.60e-01 -0.077200 7.25e-01
REACTOME GPVI MEDIATED ACTIVATION CASCADE 35 5.61e-01 -0.056800 7.25e-01
REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES 22 5.63e-01 -0.071200 7.27e-01
REACTOME RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR 19 5.64e-01 0.076400 7.28e-01
REACTOME PHOSPHOLIPID METABOLISM 201 5.65e-01 -0.023500 7.28e-01
REACTOME PEROXISOMAL LIPID METABOLISM 28 5.65e-01 -0.062800 7.28e-01
REACTOME TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE 20 5.66e-01 0.074100 7.28e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS 7 5.67e-01 -0.125000 7.28e-01
REACTOME SEMA4D IN SEMAPHORIN SIGNALING 24 5.67e-01 -0.067500 7.28e-01
REACTOME SPRY REGULATION OF FGF SIGNALING 16 5.67e-01 -0.082600 7.28e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD4 15 5.68e-01 -0.085100 7.29e-01
REACTOME INTERLEUKIN 23 SIGNALING 9 5.69e-01 0.110000 7.29e-01
REACTOME BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS 10 5.69e-01 0.104000 7.29e-01
REACTOME ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA 15 5.70e-01 -0.084700 7.29e-01
REACTOME NR1H2 AND NR1H3 MEDIATED SIGNALING 46 5.70e-01 0.048400 7.29e-01
REACTOME FERTILIZATION 26 5.71e-01 0.064100 7.30e-01
REACTOME SIGNALING BY INSULIN RECEPTOR 80 5.73e-01 -0.036400 7.32e-01
REACTOME PI3K AKT SIGNALING IN CANCER 103 5.76e-01 0.031900 7.35e-01
REACTOME VITAMIN B5 PANTOTHENATE METABOLISM 16 5.78e-01 -0.080400 7.37e-01
REACTOME FGFR2B LIGAND BINDING AND ACTIVATION 10 5.79e-01 -0.101000 7.37e-01
REACTOME TAK1 DEPENDENT IKK AND NF KAPPA B ACTIVATION 41 5.80e-01 -0.049900 7.38e-01
REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS 42 5.83e-01 0.049000 7.41e-01
REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS 123 5.86e-01 0.028500 7.44e-01
REACTOME DSCAM INTERACTIONS 11 5.88e-01 0.094300 7.47e-01
REACTOME CDC42 GTPASE CYCLE 144 5.88e-01 0.026100 7.47e-01
REACTOME SEMAPHORIN INTERACTIONS 61 5.89e-01 0.039900 7.47e-01
REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM 45 5.89e-01 -0.046500 7.47e-01
REACTOME REGULATION OF NPAS4 GENE TRANSCRIPTION 5 5.90e-01 -0.139000 7.47e-01
REACTOME NUCLEAR SIGNALING BY ERBB4 32 5.92e-01 0.054800 7.49e-01
REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB 5 5.92e-01 -0.138000 7.49e-01
REACTOME GLYCOSAMINOGLYCAN METABOLISM 118 5.94e-01 -0.028400 7.50e-01
REACTOME RA BIOSYNTHESIS PATHWAY 22 5.94e-01 0.065700 7.50e-01
REACTOME ACTIVATION OF AMPK DOWNSTREAM OF NMDARS 28 5.95e-01 0.058100 7.50e-01
REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL 13 5.95e-01 -0.085100 7.50e-01
REACTOME EICOSANOID LIGAND BINDING RECEPTORS 14 5.96e-01 -0.081900 7.50e-01
REACTOME 2 LTR CIRCLE FORMATION 7 5.98e-01 -0.115000 7.52e-01
REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING 13 5.98e-01 0.084400 7.52e-01
REACTOME RHOA GTPASE CYCLE 142 5.99e-01 -0.025600 7.52e-01
REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING 26 6.02e-01 -0.059100 7.55e-01
REACTOME INFLAMMASOMES 21 6.02e-01 -0.065700 7.55e-01
REACTOME TRAFFICKING OF AMPA RECEPTORS 29 6.04e-01 0.055600 7.57e-01
REACTOME INSULIN RECEPTOR SIGNALLING CASCADE 53 6.05e-01 0.041100 7.57e-01
REACTOME KERATAN SULFATE DEGRADATION 13 6.05e-01 0.082800 7.57e-01
REACTOME CTLA4 INHIBITORY SIGNALING 21 6.05e-01 0.065200 7.57e-01
REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 19 6.09e-01 -0.067900 7.59e-01
REACTOME DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B 7 6.09e-01 0.112000 7.59e-01
REACTOME FLT3 SIGNALING BY CBL MUTANTS 7 6.09e-01 -0.112000 7.59e-01
REACTOME EPHA MEDIATED GROWTH CONE COLLAPSE 29 6.10e-01 -0.054800 7.59e-01
REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS 39 6.10e-01 0.047200 7.59e-01
REACTOME CREB3 FACTORS ACTIVATE GENES 8 6.10e-01 -0.104000 7.59e-01
REACTOME COMMON PATHWAY OF FIBRIN CLOT FORMATION 21 6.11e-01 0.064200 7.59e-01
REACTOME INTERLEUKIN 20 FAMILY SIGNALING 25 6.11e-01 -0.058800 7.59e-01
REACTOME MASTL FACILITATES MITOTIC PROGRESSION 10 6.12e-01 -0.092700 7.59e-01
REACTOME LYSINE CATABOLISM 12 6.12e-01 0.084600 7.59e-01
REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION 10 6.12e-01 -0.092600 7.59e-01
REACTOME RAC1 GTPASE CYCLE 172 6.12e-01 -0.022400 7.59e-01
REACTOME RAB GERANYLGERANYLATION 57 6.16e-01 -0.038400 7.63e-01
REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS 11 6.17e-01 0.087100 7.64e-01
REACTOME INTERLEUKIN 35 SIGNALLING 12 6.20e-01 -0.082800 7.66e-01
REACTOME DISINHIBITION OF SNARE FORMATION 5 6.20e-01 -0.128000 7.67e-01
REACTOME DEFECTS IN BIOTIN BTN METABOLISM 8 6.21e-01 -0.101000 7.67e-01
REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING 13 6.23e-01 -0.078800 7.67e-01
REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES 34 6.23e-01 -0.048700 7.67e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS 14 6.23e-01 0.075900 7.67e-01
REACTOME P38MAPK EVENTS 13 6.23e-01 -0.078700 7.67e-01
REACTOME TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS 36 6.25e-01 -0.047100 7.67e-01
REACTOME BETA CATENIN PHOSPHORYLATION CASCADE 16 6.25e-01 -0.070500 7.67e-01
REACTOME FORMATION OF LATERAL PLATE MESODERM 5 6.25e-01 0.126000 7.67e-01
REACTOME LEISHMANIA INFECTION 156 6.25e-01 -0.022700 7.67e-01
REACTOME NEGATIVE REGULATION OF MET ACTIVITY 20 6.26e-01 -0.062900 7.68e-01
REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION 19 6.28e-01 -0.064300 7.69e-01
REACTOME REGULATION OF IFNA IFNB SIGNALING 23 6.28e-01 0.058400 7.69e-01
REACTOME DIGESTION OF DIETARY LIPID 7 6.29e-01 0.106000 7.69e-01
REACTOME PHENYLALANINE METABOLISM 6 6.30e-01 -0.114000 7.69e-01
REACTOME DEVELOPMENTAL BIOLOGY 1115 6.30e-01 0.008550 7.69e-01
REACTOME ERBB2 ACTIVATES PTK6 SIGNALING 13 6.30e-01 0.077100 7.69e-01
REACTOME SULFUR AMINO ACID METABOLISM 27 6.31e-01 -0.053400 7.69e-01
REACTOME RECEPTOR MEDIATED MITOPHAGY 10 6.31e-01 -0.087700 7.69e-01
REACTOME NEF MEDIATED CD4 DOWN REGULATION 9 6.32e-01 -0.092100 7.70e-01
REACTOME REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR 11 6.33e-01 0.083100 7.70e-01
REACTOME ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY 10 6.35e-01 -0.086700 7.70e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE 20 6.35e-01 0.061300 7.70e-01
REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS 6 6.36e-01 -0.112000 7.70e-01
REACTOME SIGNALING BY RETINOIC ACID 41 6.36e-01 -0.042800 7.70e-01
REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE 21 6.36e-01 -0.059700 7.70e-01
REACTOME IRS MEDIATED SIGNALLING 47 6.36e-01 0.039900 7.70e-01
REACTOME PROSTANOID LIGAND RECEPTORS 9 6.36e-01 -0.091100 7.70e-01
REACTOME PROTON COUPLED MONOCARBOXYLATE TRANSPORT 6 6.37e-01 -0.111000 7.71e-01
REACTOME NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 11 6.40e-01 -0.081400 7.74e-01
REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS 15 6.40e-01 -0.069600 7.74e-01
REACTOME PROLACTIN RECEPTOR SIGNALING 15 6.41e-01 -0.069500 7.74e-01
REACTOME PHASE II CONJUGATION OF COMPOUNDS 102 6.43e-01 0.026600 7.75e-01
REACTOME INTERLEUKIN 18 SIGNALING 8 6.44e-01 -0.094200 7.76e-01
REACTOME NERVOUS SYSTEM DEVELOPMENT 552 6.44e-01 -0.011500 7.76e-01
REACTOME BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA 5 6.47e-01 -0.118000 7.79e-01
REACTOME SEMA3A PAK DEPENDENT AXON REPULSION 14 6.48e-01 -0.070400 7.80e-01
REACTOME SIGNALING BY MRAS COMPLEX MUTANTS 7 6.49e-01 -0.099300 7.80e-01
REACTOME SYNTHESIS OF 15 EICOSATETRAENOIC ACID DERIVATIVES 6 6.49e-01 -0.107000 7.80e-01
REACTOME DISEASES OF GLYCOSYLATION 137 6.50e-01 0.022400 7.80e-01
REACTOME METABOLISM OF VITAMINS AND COFACTORS 185 6.51e-01 0.019300 7.81e-01
REACTOME MRNA EDITING 10 6.54e-01 0.081900 7.84e-01
REACTOME FGFR1B LIGAND BINDING AND ACTIVATION 6 6.54e-01 0.106000 7.84e-01
REACTOME MET ACTIVATES PTPN11 5 6.55e-01 -0.115000 7.84e-01
REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE 17 6.56e-01 -0.062400 7.84e-01
REACTOME PLATELET SENSITIZATION BY LDL 17 6.57e-01 -0.062200 7.85e-01
REACTOME TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY 16 6.58e-01 0.063800 7.86e-01
REACTOME PROCESSING AND ACTIVATION OF SUMO 10 6.60e-01 -0.080400 7.87e-01
REACTOME PI3K AKT ACTIVATION 9 6.60e-01 -0.084700 7.87e-01
REACTOME PYRIMIDINE SALVAGE 10 6.63e-01 -0.079500 7.91e-01
REACTOME NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 25 6.65e-01 0.050100 7.92e-01
REACTOME HS GAG DEGRADATION 19 6.67e-01 0.057100 7.93e-01
REACTOME RAP1 SIGNALLING 16 6.67e-01 -0.062000 7.93e-01
REACTOME OAS ANTIVIRAL RESPONSE 8 6.68e-01 -0.087600 7.93e-01
REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL 12 6.68e-01 0.071500 7.93e-01
REACTOME NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 11 6.68e-01 -0.074600 7.93e-01
REACTOME DARPP 32 EVENTS 24 6.71e-01 0.050100 7.95e-01
REACTOME PREDNISONE ADME 10 6.71e-01 0.077500 7.95e-01
REACTOME IRAK1 RECRUITS IKK COMPLEX 12 6.72e-01 -0.070500 7.96e-01
REACTOME CHAPERONE MEDIATED AUTOPHAGY 20 6.73e-01 -0.054600 7.96e-01
REACTOME MULTIFUNCTIONAL ANION EXCHANGERS 9 6.73e-01 -0.081200 7.96e-01
REACTOME ABACAVIR TRANSMEMBRANE TRANSPORT 5 6.74e-01 -0.109000 7.96e-01
REACTOME PLATELET AGGREGATION PLUG FORMATION 39 6.75e-01 0.038800 7.97e-01
REACTOME DEFECTIVE F9 ACTIVATION 5 6.76e-01 -0.108000 7.97e-01
REACTOME SIGNALING BY FGFR 85 6.76e-01 -0.026200 7.97e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING 11 6.79e-01 0.072100 7.99e-01
REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR 11 6.81e-01 0.071700 8.01e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES 15 6.82e-01 -0.061100 8.02e-01
REACTOME SIGNALING BY FGFR1 49 6.84e-01 0.033600 8.04e-01
REACTOME INLA MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS 9 6.86e-01 0.077800 8.05e-01
REACTOME SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA PHE 6 6.86e-01 -0.095200 8.05e-01
REACTOME NADE MODULATES DEATH SIGNALLING 5 6.87e-01 0.104000 8.05e-01
REACTOME INOSITOL PHOSPHATE METABOLISM 45 6.87e-01 -0.034700 8.05e-01
REACTOME SYNTHESIS OF PC 27 6.89e-01 -0.044600 8.06e-01
REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX 36 6.90e-01 0.038400 8.08e-01
REACTOME NETRIN 1 SIGNALING 49 6.92e-01 0.032700 8.09e-01
REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS 19 6.92e-01 -0.052500 8.09e-01
REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE 71 6.93e-01 -0.027100 8.09e-01
REACTOME NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY 6 6.94e-01 -0.092900 8.09e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE 8 6.95e-01 0.080100 8.10e-01
REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4 33 6.95e-01 -0.039400 8.10e-01
REACTOME ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING 9 6.95e-01 -0.075400 8.10e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS 7 6.96e-01 -0.085300 8.10e-01
REACTOME G2 M DNA REPLICATION CHECKPOINT 5 6.96e-01 0.101000 8.10e-01
REACTOME PRE NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM 6 6.98e-01 0.091600 8.11e-01
REACTOME FORMATION OF XYLULOSE 5 PHOSPHATE 5 6.98e-01 -0.100000 8.11e-01
REACTOME CROSS PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS PHAGOSOMES 6 7.01e-01 0.090400 8.13e-01
REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING 12 7.02e-01 0.063800 8.13e-01
REACTOME INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION 21 7.02e-01 -0.048200 8.13e-01
REACTOME UBIQUINOL BIOSYNTHESIS 8 7.04e-01 -0.077700 8.15e-01
REACTOME VITAMIN D CALCIFEROL METABOLISM 12 7.06e-01 0.062800 8.17e-01
REACTOME REGULATED PROTEOLYSIS OF P75NTR 11 7.06e-01 -0.065600 8.17e-01
REACTOME SIGNALLING TO RAS 20 7.07e-01 -0.048500 8.17e-01
REACTOME SIGNALING BY FGFR4 40 7.10e-01 0.034000 8.19e-01
REACTOME TOXICITY OF BOTULINUM TOXIN TYPE D BOTD 5 7.10e-01 0.096000 8.20e-01
REACTOME ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA 5 7.11e-01 -0.095700 8.20e-01
REACTOME CA2 PATHWAY 62 7.12e-01 0.027100 8.21e-01
REACTOME NTRK2 ACTIVATES RAC1 5 7.13e-01 -0.095000 8.21e-01
REACTOME EFFECTS OF PIP2 HYDROLYSIS 26 7.13e-01 0.041600 8.21e-01
REACTOME CHL1 INTERACTIONS 9 7.15e-01 -0.070200 8.22e-01
REACTOME CIPROFLOXACIN ADME 5 7.16e-01 -0.094100 8.22e-01
REACTOME INSULIN PROCESSING 24 7.16e-01 0.042900 8.22e-01
REACTOME IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS 17 7.17e-01 0.050800 8.22e-01
REACTOME NICOTINAMIDE SALVAGING 19 7.18e-01 0.047900 8.23e-01
REACTOME RECYCLING PATHWAY OF L1 43 7.18e-01 -0.031800 8.23e-01
REACTOME INTERFERON GAMMA SIGNALING 88 7.20e-01 -0.022100 8.25e-01
REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS 20 7.22e-01 -0.046000 8.25e-01
REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE 17 7.22e-01 -0.049800 8.25e-01
REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN 19 7.22e-01 0.047100 8.25e-01
REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE 9 7.27e-01 -0.067300 8.29e-01
REACTOME OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS 8 7.27e-01 0.071300 8.29e-01
REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX 13 7.27e-01 0.055900 8.29e-01
REACTOME ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS 10 7.28e-01 -0.063600 8.29e-01
REACTOME LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS 19 7.30e-01 -0.045700 8.31e-01
REACTOME PROLONGED ERK ACTIVATION EVENTS 14 7.31e-01 0.053000 8.32e-01
REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES 21 7.35e-01 0.042700 8.35e-01
REACTOME NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 24 7.37e-01 -0.039600 8.37e-01
REACTOME ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA 9 7.38e-01 -0.064400 8.38e-01
REACTOME MET INTERACTS WITH TNS PROTEINS 5 7.41e-01 0.085200 8.41e-01
REACTOME PLATELET CALCIUM HOMEOSTASIS 27 7.46e-01 0.036100 8.45e-01
REACTOME SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX 15 7.47e-01 -0.048100 8.47e-01
REACTOME EPH EPHRIN MEDIATED REPULSION OF CELLS 50 7.48e-01 0.026300 8.47e-01
REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS 62 7.49e-01 -0.023500 8.47e-01
REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES 12 7.50e-01 -0.053000 8.48e-01
REACTOME SPERM MOTILITY AND TAXES 9 7.51e-01 0.061100 8.48e-01
REACTOME PEROXISOMAL PROTEIN IMPORT 62 7.52e-01 -0.023200 8.49e-01
REACTOME CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND 9 7.52e-01 -0.060700 8.49e-01
REACTOME SARS COV 2 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS 12 7.53e-01 -0.052500 8.49e-01
REACTOME RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA 7 7.55e-01 -0.068200 8.50e-01
REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS 30 7.55e-01 0.032900 8.50e-01
REACTOME COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM 21 7.59e-01 -0.038600 8.54e-01
REACTOME PREVENTION OF PHAGOSOMAL LYSOSOMAL FUSION 9 7.60e-01 -0.058900 8.54e-01
REACTOME NEUROTRANSMITTER RELEASE CYCLE 48 7.61e-01 -0.025300 8.56e-01
REACTOME DEPOLYMERISATION OF THE NUCLEAR LAMINA 14 7.63e-01 0.046600 8.57e-01
REACTOME RUNX2 REGULATES CHONDROCYTE MATURATION 5 7.64e-01 0.077700 8.57e-01
REACTOME HEME BIOSYNTHESIS 13 7.64e-01 0.048000 8.57e-01
REACTOME DISORDERS OF TRANSMEMBRANE TRANSPORTERS 170 7.64e-01 -0.013300 8.57e-01
REACTOME MELANIN BIOSYNTHESIS 5 7.65e-01 0.077200 8.57e-01
REACTOME VXPX CARGO TARGETING TO CILIUM 20 7.65e-01 -0.038500 8.57e-01
REACTOME GLYCOSPHINGOLIPID METABOLISM 39 7.66e-01 0.027500 8.57e-01
REACTOME REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM 11 7.67e-01 0.051500 8.57e-01
REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS 35 7.68e-01 -0.028900 8.57e-01
REACTOME GLUTATHIONE CONJUGATION 33 7.68e-01 -0.029700 8.57e-01
REACTOME RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION 6 7.69e-01 0.069300 8.57e-01
REACTOME CS DS DEGRADATION 12 7.71e-01 0.048600 8.58e-01
REACTOME ACETYLCHOLINE REGULATES INSULIN SECRETION 10 7.71e-01 0.053200 8.58e-01
REACTOME ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS 5 7.73e-01 0.074600 8.60e-01
REACTOME BH3 ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI APOPTOTIC BCL 2 MEMBERS 9 7.76e-01 -0.054700 8.64e-01
REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS 15 7.79e-01 0.041900 8.65e-01
REACTOME AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY 8 7.79e-01 -0.057200 8.65e-01
REACTOME METHYLATION 14 7.79e-01 -0.043200 8.65e-01
REACTOME CATION COUPLED CHLORIDE COTRANSPORTERS 7 7.81e-01 -0.060800 8.66e-01
REACTOME PRE NOTCH PROCESSING IN GOLGI 18 7.86e-01 0.037000 8.71e-01
REACTOME ESTROGEN BIOSYNTHESIS 6 7.90e-01 -0.062600 8.75e-01
REACTOME CD22 MEDIATED BCR REGULATION 5 7.91e-01 0.068600 8.75e-01
REACTOME PTK6 REGULATES CELL CYCLE 6 7.92e-01 -0.062200 8.76e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FYN 7 7.93e-01 0.057300 8.77e-01
REACTOME OPSINS 7 7.94e-01 0.057100 8.77e-01
REACTOME REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS 7 7.96e-01 -0.056300 8.79e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS 14 7.97e-01 -0.039700 8.79e-01
REACTOME LIPOPHAGY 9 7.99e-01 0.048900 8.81e-01
REACTOME ASPARTATE AND ASPARAGINE METABOLISM 11 8.00e-01 0.044000 8.82e-01
REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION 13 8.01e-01 0.040400 8.82e-01
REACTOME ARYL HYDROCARBON RECEPTOR SIGNALLING 6 8.03e-01 0.058700 8.83e-01
REACTOME GAP JUNCTION DEGRADATION 12 8.04e-01 -0.041500 8.83e-01
REACTOME P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1 6 8.04e-01 -0.058600 8.83e-01
REACTOME DERMATAN SULFATE BIOSYNTHESIS 10 8.06e-01 -0.044800 8.85e-01
REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE 69 8.08e-01 0.016900 8.87e-01
REACTOME REGULATION OF KIT SIGNALING 16 8.09e-01 -0.034900 8.87e-01
REACTOME ATTENUATION PHASE 27 8.10e-01 -0.026800 8.87e-01
REACTOME SEROTONIN NEUROTRANSMITTER RELEASE CYCLE 17 8.10e-01 0.033700 8.87e-01
REACTOME DEX H BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION 7 8.15e-01 0.051100 8.91e-01
REACTOME REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS 11 8.15e-01 -0.040700 8.91e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS 12 8.15e-01 -0.038900 8.91e-01
REACTOME LIGAND RECEPTOR INTERACTIONS 8 8.16e-01 0.047600 8.91e-01
REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE 37 8.17e-01 0.022000 8.92e-01
REACTOME SIGNALING BY HIPPO 19 8.17e-01 -0.030600 8.92e-01
REACTOME KINESINS 59 8.19e-01 -0.017300 8.93e-01
REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 122 8.19e-01 0.012000 8.93e-01
REACTOME P75NTR SIGNALS VIA NF KB 15 8.21e-01 0.033800 8.94e-01
REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS 16 8.21e-01 -0.032600 8.94e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR2 29 8.22e-01 -0.024100 8.94e-01
REACTOME MITOCHONDRIAL UNCOUPLING 5 8.24e-01 -0.057600 8.95e-01
REACTOME ACTIVATION OF PPARGC1A PGC 1ALPHA BY PHOSPHORYLATION 10 8.24e-01 0.040500 8.95e-01
REACTOME EPHB MEDIATED FORWARD SIGNALING 41 8.25e-01 -0.019900 8.95e-01
REACTOME NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 22 8.26e-01 -0.027100 8.96e-01
REACTOME ERKS ARE INACTIVATED 13 8.28e-01 -0.034800 8.97e-01
REACTOME SARS COV 2 TARGETS PDZ PROTEINS IN CELL CELL JUNCTION 5 8.28e-01 -0.056000 8.97e-01
REACTOME EGFR INTERACTS WITH PHOSPHOLIPASE C GAMMA 9 8.29e-01 -0.041600 8.97e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE 5 8.29e-01 -0.055700 8.97e-01
REACTOME SIGNALING BY MAPK MUTANTS 6 8.36e-01 0.049000 9.03e-01
REACTOME VITAMIN C ASCORBATE METABOLISM 8 8.36e-01 -0.042100 9.04e-01
REACTOME VITAMIN B2 RIBOFLAVIN METABOLISM 7 8.38e-01 0.044600 9.04e-01
REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R 52 8.39e-01 0.016300 9.04e-01
REACTOME EXTRA NUCLEAR ESTROGEN SIGNALING 74 8.39e-01 0.013700 9.04e-01
REACTOME RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS 5 8.39e-01 -0.052300 9.04e-01
REACTOME APEX1 INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY 7 8.41e-01 0.043700 9.06e-01
REACTOME RUNX2 REGULATES BONE DEVELOPMENT 29 8.43e-01 -0.021200 9.07e-01
REACTOME RAF INDEPENDENT MAPK1 3 ACTIVATION 22 8.45e-01 -0.024100 9.07e-01
REACTOME GAB1 SIGNALOSOME 17 8.46e-01 -0.027300 9.07e-01
REACTOME RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY 14 8.46e-01 0.030100 9.07e-01
REACTOME SUMO IS TRANSFERRED FROM E1 TO E2 UBE2I UBC9 7 8.46e-01 -0.042400 9.07e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS 9 8.46e-01 -0.037400 9.07e-01
REACTOME FORMATION OF PARAXIAL MESODERM 22 8.49e-01 -0.023400 9.08e-01
REACTOME INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING 103 8.50e-01 -0.010800 9.08e-01
REACTOME PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1 9 8.50e-01 0.036500 9.08e-01
REACTOME PHOSPHORYLATION OF EMI1 6 8.50e-01 0.044600 9.08e-01
REACTOME FOXO MEDIATED TRANSCRIPTION 65 8.50e-01 -0.013500 9.08e-01
REACTOME LDL CLEARANCE 19 8.50e-01 0.025000 9.08e-01
REACTOME SIGNALING BY WNT IN CANCER 32 8.52e-01 0.019100 9.09e-01
REACTOME ARMS MEDIATED ACTIVATION 7 8.52e-01 0.040700 9.09e-01
REACTOME BIOSYNTHESIS OF MARESINS 8 8.54e-01 0.037700 9.10e-01
REACTOME ACTIVATION OF NIMA KINASES NEK9 NEK6 NEK7 7 8.54e-01 0.040100 9.10e-01
REACTOME MATURATION OF PROTEIN 3A 9 8.55e-01 0.035200 9.10e-01
REACTOME DEFECTIVE CHST14 CAUSES EDS MUSCULOCONTRACTURAL TYPE 7 8.55e-01 0.039800 9.10e-01
REACTOME SIGNALLING TO P38 VIA RIT AND RIN 5 8.58e-01 -0.046100 9.12e-01
REACTOME NOSTRIN MEDIATED ENOS TRAFFICKING 5 8.59e-01 0.046000 9.12e-01
REACTOME ACTIVATION OF SMO 18 8.59e-01 0.024200 9.12e-01
REACTOME ABACAVIR ADME 9 8.59e-01 0.034100 9.12e-01
REACTOME SYNTHESIS OF KETONE BODIES 8 8.60e-01 -0.035900 9.12e-01
REACTOME SIGNALING BY RNF43 MUTANTS 8 8.61e-01 0.035900 9.12e-01
REACTOME GERM LAYER FORMATION AT GASTRULATION 17 8.62e-01 0.024400 9.13e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS 34 8.62e-01 0.017200 9.13e-01
REACTOME SCAVENGING BY CLASS A RECEPTORS 19 8.64e-01 -0.022600 9.15e-01
REACTOME SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL 25 8.71e-01 0.018700 9.21e-01
REACTOME NICOTINATE METABOLISM 31 8.73e-01 0.016500 9.23e-01
REACTOME CONJUGATION OF BENZOATE WITH GLYCINE 6 8.75e-01 0.037000 9.24e-01
REACTOME PYRIMIDINE CATABOLISM 12 8.75e-01 0.026100 9.24e-01
REACTOME REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO 10 8.77e-01 0.028300 9.24e-01
REACTOME SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION 8 8.78e-01 0.031400 9.25e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE GIP 12 8.79e-01 -0.025400 9.26e-01
REACTOME UREA CYCLE 9 8.81e-01 -0.028700 9.28e-01
REACTOME BETA OXIDATION OF BUTANOYL COA TO ACETYL COA 5 8.83e-01 0.038100 9.29e-01
REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS 45 8.84e-01 -0.012600 9.29e-01
REACTOME MISCELLANEOUS TRANSPORT AND BINDING EVENTS 24 8.86e-01 -0.016900 9.30e-01
REACTOME DCC MEDIATED ATTRACTIVE SIGNALING 14 8.86e-01 0.022100 9.30e-01
REACTOME INTERLEUKIN 37 SIGNALING 20 8.87e-01 -0.018400 9.30e-01
REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS 12 8.96e-01 -0.021900 9.39e-01
REACTOME SEROTONIN RECEPTORS 11 8.96e-01 0.022700 9.39e-01
REACTOME UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN 6 8.98e-01 -0.030400 9.40e-01
REACTOME PROTEIN FOLDING 96 8.98e-01 -0.007540 9.40e-01
REACTOME SIGNALING BY MET 78 9.01e-01 0.008160 9.42e-01
REACTOME SYNTHESIS OF 5 EICOSATETRAENOIC ACIDS 9 9.02e-01 0.023600 9.43e-01
REACTOME METAL ION SLC TRANSPORTERS 23 9.07e-01 0.014100 9.47e-01
REACTOME IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN 5 9.07e-01 -0.030000 9.47e-01
REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA 11 9.08e-01 0.020200 9.47e-01
REACTOME HDL CLEARANCE 5 9.08e-01 -0.029800 9.47e-01
REACTOME FCGR ACTIVATION 11 9.11e-01 0.019400 9.50e-01
REACTOME CHREBP ACTIVATES METABOLIC GENE EXPRESSION 8 9.14e-01 0.022000 9.51e-01
REACTOME UPTAKE AND ACTIONS OF BACTERIAL TOXINS 28 9.14e-01 0.011800 9.51e-01
REACTOME NEUROTRANSMITTER CLEARANCE 9 9.14e-01 0.020700 9.51e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS 5 9.15e-01 -0.027700 9.51e-01
REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY 23 9.17e-01 0.012500 9.53e-01
REACTOME RUNX3 REGULATES CDKN1A TRANSCRIPTION 7 9.20e-01 0.021900 9.55e-01
REACTOME LDL REMODELING 6 9.20e-01 -0.023600 9.55e-01
REACTOME HEMOSTASIS 591 9.22e-01 -0.002360 9.56e-01
REACTOME SIGNALING BY NOTCH3 48 9.23e-01 -0.008070 9.56e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN 13 9.23e-01 -0.015400 9.56e-01
REACTOME SPHINGOLIPID METABOLISM 84 9.24e-01 0.006040 9.56e-01
REACTOME SIGNALING BY FGFR3 39 9.28e-01 -0.008390 9.59e-01
REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION 16 9.30e-01 -0.012800 9.60e-01
REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS 21 9.30e-01 -0.011100 9.60e-01
REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE 24 9.32e-01 0.010000 9.62e-01
REACTOME PP2A MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS 6 9.33e-01 -0.019700 9.63e-01
REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING 89 9.38e-01 0.004750 9.67e-01
REACTOME COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING 38 9.41e-01 0.006990 9.69e-01
REACTOME CD28 DEPENDENT VAV1 PATHWAY 11 9.42e-01 -0.012600 9.70e-01
REACTOME NEUROFASCIN INTERACTIONS 6 9.43e-01 0.016700 9.71e-01
REACTOME KERATAN SULFATE BIOSYNTHESIS 28 9.45e-01 -0.007580 9.71e-01
REACTOME DEFECTIVE B4GALT1 CAUSES B4GALT1 CDG CDG 2D 8 9.48e-01 -0.013300 9.74e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH PI3K 6 9.49e-01 0.015000 9.75e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE 5 9.50e-01 -0.016300 9.75e-01
REACTOME BETA DEFENSINS 27 9.52e-01 0.006730 9.75e-01
REACTOME SIGNAL ATTENUATION 10 9.52e-01 0.010900 9.75e-01
REACTOME IKBA VARIANT LEADS TO EDA ID 6 9.52e-01 0.014000 9.75e-01
REACTOME METABOLISM OF STEROID HORMONES 35 9.53e-01 -0.005770 9.75e-01
REACTOME VITAMIN B1 THIAMIN METABOLISM 5 9.54e-01 0.015000 9.75e-01
REACTOME NEUROTOXICITY OF CLOSTRIDIUM TOXINS 10 9.54e-01 0.010600 9.75e-01
REACTOME SCAVENGING BY CLASS B RECEPTORS 6 9.56e-01 0.013100 9.75e-01
REACTOME ROBO RECEPTORS BIND AKAP5 9 9.56e-01 -0.010600 9.75e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH CDK5 6 9.56e-01 -0.013000 9.75e-01
REACTOME SUMOYLATION OF IMMUNE RESPONSE PROTEINS 10 9.56e-01 -0.010000 9.75e-01
REACTOME DISEASES OF IMMUNE SYSTEM 29 9.57e-01 0.005830 9.75e-01
REACTOME NEGATIVE REGULATION OF FLT3 15 9.57e-01 -0.008020 9.75e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING 25 9.60e-01 -0.005860 9.77e-01
REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION 26 9.62e-01 0.005350 9.78e-01
REACTOME HSF1 ACTIVATION 29 9.63e-01 -0.005010 9.78e-01
REACTOME SYNTHESIS OF PIPS AT THE ER MEMBRANE 5 9.63e-01 0.012000 9.78e-01
REACTOME NEGATIVE REGULATION OF ACTIVITY OF TFAP2 AP 2 FAMILY TRANSCRIPTION FACTORS 10 9.64e-01 -0.008350 9.78e-01
REACTOME GLYCEROPHOSPHOLIPID CATABOLISM 7 9.64e-01 0.009750 9.78e-01
REACTOME KERATAN SULFATE KERATIN METABOLISM 34 9.65e-01 0.004320 9.78e-01
REACTOME ZINC TRANSPORTERS 15 9.65e-01 -0.006470 9.78e-01
REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS 8 9.66e-01 -0.008740 9.78e-01
REACTOME INTERLEUKIN 2 SIGNALING 11 9.66e-01 -0.007420 9.78e-01
REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION 10 9.68e-01 -0.007440 9.78e-01
REACTOME UPTAKE AND FUNCTION OF ANTHRAX TOXINS 11 9.68e-01 -0.007010 9.78e-01
REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS 12 9.68e-01 0.006690 9.78e-01
REACTOME ERBB2 REGULATES CELL MOTILITY 15 9.70e-01 -0.005550 9.80e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY DVL INTERACTING PROTEINS 5 9.71e-01 0.009380 9.80e-01
REACTOME DEFECTIVE CHSY1 CAUSES TPBS 7 9.72e-01 0.007710 9.80e-01
REACTOME PTK6 EXPRESSION 5 9.74e-01 0.008560 9.81e-01
REACTOME PURINE CATABOLISM 17 9.74e-01 -0.004630 9.81e-01
REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION 6 9.75e-01 0.007530 9.81e-01
REACTOME INTEGRIN SIGNALING 27 9.75e-01 -0.003510 9.81e-01
REACTOME THE ACTIVATION OF ARYLSULFATASES 8 9.78e-01 0.005740 9.83e-01
REACTOME METABOLISM OF INGESTED SEMET SEC MESEC INTO H2SE 7 9.78e-01 0.006050 9.83e-01
REACTOME SIGNALING BY ACTIVIN 15 9.80e-01 0.003750 9.84e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG 7 9.81e-01 -0.005120 9.85e-01
REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM 50 9.82e-01 0.001810 9.85e-01
REACTOME NEF AND SIGNAL TRANSDUCTION 8 9.87e-01 -0.003320 9.89e-01
REACTOME DISEASES OF CARBOHYDRATE METABOLISM 31 9.91e-01 -0.001220 9.92e-01
REACTOME RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES TREGS 9 9.91e-01 0.002190 9.92e-01
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION 250 9.91e-01 -0.000404 9.92e-01
REACTOME RHO GTPASES ACTIVATE IQGAPS 31 9.97e-01 0.000373 9.97e-01


Detailed Gene set reports



REACTOME_METABOLISM_OF_RNA

REACTOME_METABOLISM_OF_RNA
1313
set REACTOME_METABOLISM_OF_RNA
setSize 675
pANOVA 1.68e-31
s.dist -0.263
p.adjustANOVA 2.76e-28



Top enriched genes

Top 20 genes
GeneID Gene Rank
SNRPN -11091
RPL10L -11011
TNFSF13 -10944
PRPF6 -10912
GLE1 -10854
THG1L -10799
CNOT11 -10716
FAM32A -10709
SMG5 -10684
PSMB7 -10651
RPL35A -10631
PSMC6 -10621
PRCC -10612
LSM1 -10525
RPL37A -10509
GEMIN2 -10426
TYW1 -10391
CPSF2 -10273
CNOT6L -10244
WDR36 -10218

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SNRPN -11091.0
RPL10L -11011.0
TNFSF13 -10944.0
PRPF6 -10912.0
GLE1 -10854.0
THG1L -10799.0
CNOT11 -10716.0
FAM32A -10709.0
SMG5 -10684.0
PSMB7 -10651.0
RPL35A -10631.0
PSMC6 -10621.0
PRCC -10612.0
LSM1 -10525.0
RPL37A -10509.0
GEMIN2 -10426.0
TYW1 -10391.0
CPSF2 -10273.0
CNOT6L -10244.0
WDR36 -10218.0
PSMD2 -10209.0
PELP1 -10186.0
RIOK2 -10097.0
PSMC2 -10087.0
ZMAT5 -10078.0
PNRC2 -10055.0
RBM8A -10008.0
SET -10005.0
EDC3 -9872.0
THOC7 -9867.0
SLU7 -9843.0
MAGOHB -9842.0
PSMA3 -9831.0
MAGOH -9827.0
FAM98B -9780.0
U2AF1L4 -9732.0
HNRNPU -9717.0
PCBP1 -9650.0
MAPK14 -9643.0
TRMT13 -9624.0
RPL11 -9622.0
RIOK3 -9618.0
PSMB8 -9616.0
TRMU -9599.0
PRKRIP1 -9544.0
RPS5 -9536.0
RNGTT -9516.0
HNRNPA3 -9498.0
LSM7 -9451.0
RPP25 -9431.0
TRMT6 -9422.0
PSME1 -9420.0
DDX6 -9400.0
SMG8 -9385.0
KRR1 -9372.0
ERCC3 -9371.0
TNPO1 -9369.0
ERI1 -9352.0
EPRS1 -9324.0
PSMC5 -9310.0
NUP37 -9289.0
PHAX -9282.0
APOBEC3C -9277.0
LSM3 -9276.0
POLDIP3 -9265.0
SRSF8 -9253.0
EXOSC7 -9248.0
YWHAZ -9228.0
UTP6 -9227.0
RNPC3 -9198.0
U2SURP -9195.0
PUS3 -9190.0
GPATCH1 -9141.0
PRPF19 -9140.0
RPP30 -9130.0
THUMPD1 -9117.0
GEMIN6 -9104.0
SMG7 -9094.0
CSNK1D -9073.0
HSPA1A -9068.0
RPS23 -9056.0
UTP11 -9050.0
PSMA8 -9037.0
PPIH -9013.0
RTCB -8927.0
PATL1 -8878.0
RPL24 -8875.0
NUP50 -8870.0
ACIN1 -8816.0
TEX10 -8792.0
SRSF11 -8791.0
RPL32 -8790.0
PLRG1 -8783.0
TP53RK -8749.0
RCL1 -8732.0
TSEN34 -8729.0
KHSRP -8722.0
LSM10 -8708.0
POM121 -8700.0
ZFP36L1 -8698.0
XRN2 -8689.0
HNRNPA1 -8664.0
PSME3 -8645.0
RPL4 -8640.0
SRSF10 -8621.0
AQR -8601.0
CTNNBL1 -8580.0
URM1 -8548.0
RPL23A -8537.0
WBP11 -8531.0
EXOSC10 -8526.0
PSMD3 -8488.0
DHX35 -8474.0
UPF3A -8473.0
ADAT3 -8465.0
SNRNP200 -8455.0
GTF2H3 -8449.0
WDR12 -8411.0
NUP42 -8381.0
NOL12 -8375.0
WBP4 -8359.0
POP7 -8302.0
UBC -8277.0
PAN3 -8261.0
UTP18 -8231.0
CNOT1 -8226.0
CWC27 -8217.0
NCBP1 -8209.0
FAU -8194.0
THADA -8188.0
IMP4 -8142.0
SEH1L -8137.0
NUP98 -8136.0
SRRM1 -8132.0
PPP1R8 -8131.0
FTSJ3 -8090.0
SAP18 -8083.0
SNU13 -8074.0
RPL23 -8055.0
PSMD6 -8047.0
RPL13 -8037.0
FCF1 -8005.0
LSM5 -7999.0
NUP107 -7996.0
NHP2 -7974.0
CDC40 -7930.0
CPSF6 -7910.0
MTO1 -7906.0
DDX20 -7891.0
RRP1 -7885.0
EXOSC4 -7820.0
ERCC2 -7814.0
RBM28 -7737.0
DDX23 -7726.0
SENP3 -7699.0
GTF2H1 -7675.0
MNAT1 -7673.0
MTERF4 -7672.0
WDR43 -7670.0
SNRPB -7665.0
PRPF4 -7649.0
PSMB10 -7549.0
TSEN2 -7544.0
CCNH -7537.0
LSM4 -7499.0
PSMD7 -7470.0
SF3B3 -7426.0
RPL7A -7402.0
PSMB5 -7376.0
CNOT3 -7373.0
QTRT2 -7341.0
CNOT6 -7337.0
RPL35 -7326.0
RPL31 -7280.0
SNRPB2 -7268.0
DNAJC8 -7255.0
PARN -7228.0
BUD31 -7222.0
CNOT2 -7216.0
RPS26 -7213.0
NOP2 -7204.0
YJU2 -7193.0
RRP36 -7171.0
HNRNPK -7107.0
NOB1 -7091.0
PRPF3 -7055.0
ELAVL1 -7039.0
LENG1 -7009.0
EMG1 -7006.0
PSMB2 -7000.0
PSMB9 -6985.0
CTU2 -6984.0
SART1 -6980.0
PSMD9 -6972.0
TUT7 -6950.0
RPP14 -6913.0
NUP214 -6894.0
CACTIN -6893.0
POLR2H -6881.0
RPSA -6847.0
EIF4G1 -6824.0
NXT1 -6818.0
SRSF6 -6815.0
UTP3 -6743.0
RBM22 -6693.0
NSUN4 -6688.0
DHX15 -6668.0
RPL36 -6664.0
SMG6 -6650.0
RBM7 -6601.0
DHX38 -6598.0
RPS28 -6540.0
SNRNP40 -6509.0
HEATR1 -6477.0
NUP160 -6475.0
SEC13 -6469.0
CASC3 -6442.0
PABPC1 -6425.0
UTP15 -6383.0
DDX49 -6244.0
RAE1 -6238.0
DIS3 -6209.0
GEMIN7 -6183.0
SNRNP27 -6143.0
CSTF1 -6141.0
HNRNPA2B1 -6137.0
NT5C3B -6121.0
EFTUD2 -6109.0
PSMC3 -6093.0
RPL21 -6077.0
GNL3 -6053.0
ADAR -6044.0
C2orf49 -5993.0
RPL30 -5982.0
POLR2L -5972.0
BCAS2 -5923.0
PSMD13 -5903.0
DDX42 -5805.0
HSPA8 -5803.0
LTV1 -5766.0
RPL26 -5760.0
NUP155 -5740.0
APOBEC4 -5732.0
SUGP1 -5652.0
CWC15 -5642.0
POLR2K -5634.0
DCPS -5632.0
LSM11 -5620.0
SRSF1 -5591.0
HNRNPH1 -5540.0
RPL10A -5530.0
NUP88 -5526.0
SRSF5 -5500.0
SRSF9 -5477.0
CPSF7 -5460.0
RPPH1 -5458.0
MRM3 -5444.0
PCF11 -5367.0
ETF1 -5364.0
THOC1 -5330.0
ANP32A -5321.0
SNRNP70 -5300.0
C1D -5297.0
RPS15 -5286.0
CDK7 -5280.0
SF3A2 -5259.0
CNOT10 -5184.0
PRPF38A -5148.0
PSMA2 -5113.0
PSMD8 -5084.0
CWF19L2 -5080.0
TUT4 -5071.0
UBL5 -5053.0
WTAP -5007.0
MRM2 -4995.0
RPL19 -4989.0
ZC3H11A -4971.0
UTP14C -4942.0
RPLP0 -4937.0
PWP2 -4916.0
MFAP1 -4901.0
SKIC3 -4897.0
EXOSC2 -4886.0
RPS12 -4819.0
PRORP -4791.0
LSM6 -4786.0
RPS16 -4777.0
NIP7 -4728.0
TRNT1 -4718.0
SKIC2 -4701.0
IMP3 -4695.0
HBS1L -4694.0
THOC5 -4659.0
TRA2B -4639.0
SRRM2 -4633.0
SNRPA -4631.0
WDR77 -4626.0
PSMA1 -4584.0
CNOT9 -4525.0
RPL36AL -4483.5
CPSF1 -4480.0
PPIL3 -4467.0
NOP58 -4464.0
RPS10 -4458.0
RPL7 -4455.0
CWC25 -4443.0
NUP58 -4439.0
RAN -4434.0
RBM25 -4431.0
EXOSC5 -4400.0
CLP1 -4376.0
SNRPA1 -4363.0
RPS6 -4356.0
WDR3 -4332.0
POP5 -4300.0
HNRNPD -4277.0
RPS27L -4266.0
POP1 -4212.0
TCERG1 -4147.0
SDE2 -4118.0
TYW5 -4116.0
SNRPD3 -4100.0
CDC5L -4089.0
RPL18 -4060.0
PSMB3 -4011.0
EXOSC9 -3979.0
RTRAF -3977.0
EXOSC6 -3940.0
POLR2G -3937.0
NUP188 -3926.0
MRM1 -3896.0
HNRNPM -3894.0
TRMT11 -3881.0
RPS21 -3875.0
DCP1A -3856.0
PCBP2 -3820.0
GAR1 -3815.0
PSME4 -3807.0
RPP40 -3791.0
RPS8 -3769.0
POLR2B -3768.0
RPS18 -3746.0
WDR75 -3741.0
ZCRB1 -3735.0
DIMT1 -3720.0
RPL17 -3669.0
UPF2 -3660.0
DCAF13 -3631.0
MTREX -3624.0
TFB1M -3491.0
RBM39 -3444.0
DHX8 -3434.0
XPO1 -3414.0
SYF2 -3389.0
BOP1 -3328.0
HNRNPL -3278.0
SF3B1 -3274.0
HNRNPR -3271.0
DHX16 -3257.0
TSEN54 -3255.0
CNOT4 -3192.0
PSMB1 -3117.0
TSEN15 -3109.0
EBNA1BP2 -3087.0
RPL27 -3082.0
SRSF3 -3037.0
UTP25 -2986.0
PAPOLA -2927.0
NSUN2 -2916.0
SLBP -2909.0
TRMT10C -2830.0
ZNF830 -2810.0
DDX46 -2803.0
ZFP36 -2775.0
EXOSC3 -2772.0
SNRPD2 -2767.0
GTF2F2 -2764.0
PSMA7 -2759.0
PPWD1 -2653.0
SF3B6 -2621.0
UTP20 -2609.0
TSR3 -2583.0
WDR70 -2575.0
RPL14 -2574.0
RPLP2 -2532.0
PSMF1 -2512.0
PABPN1 -2472.0
NOL11 -2462.0
NCBP2 -2442.0
GEMIN4 -2339.0
DDX41 -2322.0
PPP2R1A -2279.0
SYMPK -2275.0
DHX37 -2258.0
AKT1 -2241.0
SNRNP35 -2217.0
FBL -2120.0
SRSF2 -2063.0
DDX1 -1981.0
BUD13 -1934.0
EIF4B -1889.0
PSMC1 -1839.0
CCAR1 -1820.0
PSMA6 -1800.0
TGS1 -1797.0
DCP2 -1775.0
POLR2I -1736.0
U2AF2 -1675.0
TRMT9B -1666.0
ALKBH8 -1665.0
CDKAL1 -1623.0
RBM17 -1617.0
PPIG -1581.0
LSM2 -1573.0
CHERP -1569.0
ISG20L2 -1566.0
GTPBP3 -1556.0
WDR4 -1547.0
UTP4 -1525.0
AAAS -1523.0
RPS20 -1511.0
PAN2 -1499.0
SF1 -1455.0
IGF2BP3 -1441.0
SNRPE -1363.0
RPS9 -1361.0
RPL5 -1340.0
MPHOSPH6 -1305.0
TPR -1291.0
POLR2A -1290.0
TPRKB -1287.0
PTBP1 -1245.0
MAPKAPK2 -1227.0
THOC6 -1219.0
RANBP2 -1170.0
SF3A3 -1166.0
ADAT2 -1159.0
TRMT1 -1140.0
A1CF -1088.0
CTU1 -1086.0
RBM42 -1060.0
LUC7L3 -1040.0
SMG9 -1021.0
NCL -1018.0
SUPT5H -997.0
EXOSC8 -994.0
SRSF7 -970.0
BUD23 -952.0
RPL8 -941.0
NUP153 -930.0
HNRNPC -921.0
NUP93 -887.0
PSMD1 -818.0
GTF2H5 -806.0
PRKCD -789.0
SARNP -780.0
RPS11 -773.0
METTL3 -684.0
RIOK1 -677.0
CWC22 -672.0
UBB -665.0
PSMA4 -648.0
NDC1 -624.0
RPS14 -538.0
PHF5A -537.0
CCDC12 -467.0
XAB2 -464.0
SRSF4 -453.0
TSR1 -440.0
DDX21 -396.0
MPHOSPH10 -355.0
PNN -311.0
TRMT112 -273.0
NSUN6 -192.0
TRMT12 -186.0
SNIP1 -152.0
SNRPD1 -139.0
RPS27A -126.0
PDCD7 -93.0
DCP1B -77.0
PPP2CA -76.0
QTRT1 -37.0
TXNL4A -12.0
ZBTB8OS 10.0
SNW1 45.0
ADAT1 101.0
LSM8 105.0
TYW3 107.0
CNOT8 131.0
PPP2R2A 137.0
NSRP1 165.0
RPLP1 175.0
GTF2H4 183.0
TBL3 184.0
RPS7 193.0
POLR2C 198.0
IGF2BP1 249.0
ELAC2 281.0
RPL12 342.0
YBX1 363.0
FYTTD1 374.0
PNO1 434.0
ALYREF 481.0
POLR2E 503.0
TRMT10A 554.0
EIF4A2 560.0
METTL1 587.0
YWHAB 626.0
DDX39B 742.0
PRKCA 781.0
RPS19 887.0
FUS 916.0
GTF2F1 936.0
PRPF8 962.0
SNRPG 982.0
PSMD11 1023.0
C9orf78 1075.0
TNKS1BP1 1103.0
SRRT 1110.0
GEMIN5 1111.0
CPSF4 1150.0
PDCD11 1162.0
NUP43 1180.0
CNOT7 1183.0
SMG1 1219.0
NXF1 1263.0
RPL15 1283.0
PSMB4 1285.0
RPL28 1298.0
PSMA5 1304.0
PUS1 1343.0
SF3B4 1361.0
HNRNPF 1389.0
ADARB1 1392.0
IK 1451.0
RPL22 1475.0
NOL6 1478.0
TRMT61A 1523.0
PSMC4 1596.0
PRPF40A 1662.0
CSTF3 1711.0
TRMT44 1745.0
DDX47 1771.0
PES1 1930.0
NOP14 1995.0
SKIC8 2035.0
PRPF31 2074.0
NAT10 2078.0
WDR46 2080.0
PSME2 2084.0
APOBEC3A 2096.0
SF3A1 2123.0
RPL41 2146.0
RPL37 2151.0
RPS27 2171.0
DHX9 2178.0
NOL9 2197.0
EXOSC1 2226.0
CSTF2T 2262.0
NUDT21 2268.0
CPSF3 2301.0
HSPB1 2306.0
RPS15A 2354.0
POLR2D 2370.0
NUP85 2430.0
ZMAT2 2436.0
RPS29 2538.0
RPS3 2573.0
RPL34 2588.0
TRMT5 2707.0
EIF4A3 2759.0
RPL27A 2771.0
SNUPN 2781.0
NUP205 2803.0
PSMD12 2806.0
CLNS1A 2843.0
RRP7A 2943.0
OSGEP 2986.0
GCFC2 3011.0
IGF2BP2 3048.0
EIF4A1 3107.0
NUP133 3158.0
POLR2F 3184.0
FIP1L1 3206.0
RPP21 3226.0
NUP54 3235.0
NUP210 3259.0
RPP38 3277.0
TRMT61B 3282.0
GSPT1 3392.0
TRIT1 3404.0
RPS3A 3411.0
PPIL2 3436.0
EIF4E 3533.0
DDX39A 3574.0
RPS13 3598.0
SNRPC 3646.0
POLR2J 3674.0
PSMD14 3679.0
PRMT5 3698.0
LCMT2 3748.0
RPS2 3762.0
DDX52 3848.0
DUS2 3898.0
BMS1 3971.0
DDX5 3974.0
NOP10 3980.0
CHTOP 3988.0
RPL6 4045.0
RNPS1 4053.0
RPS25 4057.0
WDR18 4069.0
PPIL4 4125.0
EDC4 4155.0
CRNKL1 4175.0
RPL26L1 4216.0
RPS24 4241.0
PSMB6 4375.0
PUF60 4461.0
SF3B2 4465.0
UPF1 4481.0
WDR33 4577.0
MAPK11 4578.0
APOBEC3B 4583.0
RPL22L1 4607.0
APOBEC1 4626.0
RBM5 4683.0
RPL18A 4718.0
RRP9 4739.0
NUP35 4792.0
RPL38 4807.0
SNRPF 4945.0
SMN1 5068.5
SMN2 5068.5
THOC3 5094.0
RPL9 5114.0
CSNK1E 5169.0
RNMT 5190.0
XRN1 5195.0
PPIE 5253.0
SNRNP48 5274.0
SNRNP25 5356.0
APOBEC3H 5366.0
NUP62 5471.0
NOP56 5614.0
XPOT 5622.0
ZNF473 5628.0
SEM1 5631.0
SMNDC1 5774.0
POP4 5783.0
PRPF18 5788.0
TFIP11 5846.0
USP39 5857.0
PUS7 6086.0
RPL39L 6167.0
PSMD4 6169.0
RPL3 6195.0
METTL14 6243.0
PAIP1 6256.0
UBA52 6282.0
BYSL 6303.0
RPL13A 6422.5
ISY1 6542.0
TRDMT1 6604.0
SF3B5 6672.0
PSMD5 6795.0
NOC4L 6906.0
PPIL1 7207.0
SRSF12 8178.0
POM121C 8315.0
RPL29 8479.0
SMU1 8799.0
PSMB11 9506.0
APOBEC2 10002.0
RPL3L 10336.0


REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION
1161
set REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION
setSize 1336
pANOVA 4.99e-29
s.dist -0.182
p.adjustANOVA 4.1e-26



Top enriched genes

Top 20 genes
GeneID Gene Rank
NFE2 -11221
ZNF676 -11187
L3MBTL1 -11185
CGB8 -11122
ZNF577 -11042
H2BC14 -11029
ZNF735 -11019
ZNF124 -10920
H3C6 -10917
ZFP37 -10915
H3C12 -10877
ZNF417 -10868
ZNF479 -10839
ZNF429 -10838
H3C3 -10808
ZNF418 -10806
ZNF737 -10797
IL3 -10796
ZNF439 -10778
ZNF383 -10776

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NFE2 -11221.0
ZNF676 -11187.0
L3MBTL1 -11185.0
CGB8 -11122.0
ZNF577 -11042.0
H2BC14 -11029.0
ZNF735 -11019.0
ZNF124 -10920.0
H3C6 -10917.0
ZFP37 -10915.0
H3C12 -10877.0
ZNF417 -10868.0
ZNF479 -10839.0
ZNF429 -10838.0
H3C3 -10808.0
ZNF418 -10806.0
ZNF737 -10797.0
IL3 -10796.0
ZNF439 -10778.0
ZNF383 -10776.0
MIR24-2 -10766.0
H2AC14 -10727.0
CNOT11 -10716.0
RRM2B -10668.0
MAML1 -10658.0
ZNF597 -10655.0
PSMB7 -10651.0
ZIM2 -10632.0
PSMC6 -10621.0
MEAF6 -10616.0
CASP6 -10602.0
SPI1 -10569.0
TXN -10530.0
ZNF331 -10522.0
ZNF43 -10496.0
ZNF138 -10478.0
COX18 -10439.0
ASH2L -10434.0
ZNF426 -10431.0
FKBP5 -10385.0
MIR27A -10381.0
H2BC6 -10375.0
ZNF530 -10369.0
ZNF202 -10363.0
ZNF717 -10362.0
ZNF100 -10349.0
GP1BA -10343.0
H2AC18 -10337.5
H2AC19 -10337.5
MED25 -10335.0
H4C9 -10304.0
MOV10 -10287.0
CPSF2 -10273.0
GTF2A2 -10268.0
MED31 -10247.0
H2BC12 -10245.0
CNOT6L -10244.0
ZNF655 -10216.0
PSMD2 -10209.0
H2AC20 -10208.0
BRCA1 -10206.0
H2BC15 -10189.0
OPRK1 -10174.0
ZNF560 -10173.0
FZR1 -10150.0
ZNF70 -10145.0
TAL1 -10125.0
SNAPC2 -10110.0
ZNF699 -10104.0
E2F6 -10093.0
PSMC2 -10087.0
RB1 -10080.0
INTS8 -10077.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
RBM8A -10008.0
ZNF382 -9996.0
CSNK2A2 -9986.0
MAF -9966.0
LAMTOR3 -9915.0
SYT10 -9888.0
ZNF433 -9885.0
SMARCD1 -9882.0
EAF2 -9869.0
ZNF671 -9868.0
THOC7 -9867.0
ELOB -9858.0
SLU7 -9843.0
MAGOHB -9842.0
ZNF226 -9836.0
PSMA3 -9831.0
SOCS3 -9829.0
MAGOH -9827.0
GATA3 -9812.0
SUPT16H -9810.0
U2AF1L4 -9732.0
PCGF5 -9731.0
ZNF785 -9727.0
KRAS -9725.0
ZNF443 -9710.0
ZNF677 -9706.0
CDK6 -9698.0
SP1 -9694.0
GADD45A -9677.0
EP300 -9652.0
CCNE2 -9649.0
MED6 -9648.0
MAPK14 -9643.0
ZNF746 -9629.0
PSMB8 -9616.0
MAP2K6 -9611.0
RTF1 -9598.0
NR2C2 -9586.0
YY1 -9573.0
RNGTT -9516.0
ZNF350 -9496.0
HUS1 -9493.0
IL6 -9492.0
PIN1 -9485.0
ZNF221 -9468.0
ITGBL1 -9423.0
PSME1 -9420.0
ZNF587 -9412.0
ZNF649 -9388.0
ZNF416 -9382.0
MED30 -9373.0
ERCC3 -9371.0
NELFB -9365.0
H2BC26 -9346.0
HES1 -9337.0
ARID2 -9334.0
ZNF790 -9326.0
TP53I3 -9321.0
TP53BP2 -9317.0
PSMC5 -9310.0
H2BC4 -9285.0
PHAX -9282.0
POLDIP3 -9265.0
HTT -9255.0
E2F5 -9245.0
TCF12 -9243.0
YWHAZ -9228.0
CASP10 -9224.0
SCO2 -9217.0
GPS2 -9206.0
ZNF778 -9203.0
ZNF92 -9180.0
ELF1 -9151.0
ZNF30 -9114.0
ZNF155 -9102.0
ELL2 -9098.0
ZNF724 -9092.0
PLK3 -9091.0
CBX5 -9089.0
SCO1 -9085.0
ZNF557 -9080.0
MYB -9069.0
ZNF600 -9065.0
ANAPC16 -9057.0
PSMA8 -9037.0
H2BC9 -9020.5
H3C7 -9020.5
INTS9 -9011.0
KMT2C -8999.0
MED24 -8985.0
ZNF480 -8976.0
PCGF6 -8965.0
ZNF599 -8944.0
SRF -8938.0
ZFP30 -8937.0
RNU12 -8912.0
LAMTOR2 -8879.0
WWP1 -8849.0
ZNF333 -8812.0
ZNF549 -8805.0
SRSF11 -8791.0
ZNF703 -8787.0
BMI1 -8777.0
ZNF420 -8767.0
TP53RK -8749.0
ZNF584 -8744.0
RBM14 -8742.0
ZNF300 -8734.0
CDC23 -8726.0
EXO1 -8718.0
ZNF589 -8709.0
LSM10 -8708.0
ZNF75A -8699.0
ZNF514 -8691.0
SMARCD2 -8686.0
SIN3A -8665.0
CCNG2 -8654.0
PSME3 -8645.0
GATA2 -8618.0
ZNF175 -8607.0
MLLT3 -8600.0
SUZ12 -8594.0
ZSCAN32 -8575.0
H2BC3 -8572.0
CDK12 -8566.0
ZNF77 -8554.0
PSMD3 -8488.0
BAX -8467.0
H4C3 -8451.0
GTF2H3 -8449.0
COX7A2L -8438.0
ZNF627 -8431.0
H2AC6 -8428.0
LAMTOR4 -8388.0
MIR24-1 -8349.0
NR4A2 -8347.0
PRKAA1 -8315.0
PCNA -8301.0
NAMPT -8295.0
BNIP3L -8294.0
MIR132 -8284.0
ZNF750 -8280.0
UBC -8277.0
RMI2 -8269.0
TAF3 -8256.0
INTS6 -8255.0
RUNX1 -8234.0
CNOT1 -8226.0
PAF1 -8221.0
NCBP1 -8209.0
H2BC10 -8174.0
SREBF1 -8168.0
ZNF440 -8164.0
SRRM1 -8132.0
PRMT1 -8128.0
CDK8 -8120.0
KAT5 -8114.0
ANAPC7 -8113.0
SMAD3 -8098.0
KMT5A -8065.0
PSMD6 -8047.0
SMARCE1 -8044.0
SETD9 -8040.0
RAD9A -8023.0
TMEM219 -8017.0
LIFR -7997.0
COX11 -7946.0
CBFB -7940.0
CDC40 -7930.0
FAS -7922.0
CPSF6 -7910.0
RFFL -7908.0
ZNF263 -7886.0
PLAGL1 -7863.0
YAF2 -7861.0
TAF10 -7853.0
HDAC10 -7850.0
MSTN -7839.0
ZNF563 -7828.0
CDK2 -7826.0
KAT6A -7825.0
ERCC2 -7814.0
INTS14 -7796.0
NPM1 -7766.0
ZNF658 -7758.0
CSNK2B -7734.0
SIN3B -7729.0
TNRC6B -7724.0
MRE11 -7695.0
RXRB -7679.0
GTF2H1 -7675.0
MNAT1 -7673.0
SNRPB -7665.0
GTF2B -7664.0
H4C11 -7658.0
UBE2D3 -7616.0
RFC3 -7597.0
ARNT -7593.0
RNF34 -7588.0
H2BC13 -7580.0
AGO4 -7579.0
PSMB10 -7549.0
CCNH -7537.0
ZNF264 -7525.0
RAD51 -7507.0
H3C1 -7492.0
PSMD7 -7470.0
HSPD1 -7463.0
NABP1 -7457.0
SMAD4 -7434.0
CCNT2 -7431.0
ITCH -7429.0
CTDP1 -7416.0
CDC16 -7384.0
PSMB5 -7376.0
CNOT3 -7373.0
ZNF624 -7372.0
ZNF749 -7352.0
NBN -7344.0
H2BC5 -7339.0
CNOT6 -7337.0
ZNF585A -7307.0
KAT2B -7302.0
YWHAG -7293.0
COX4I1 -7276.0
RBBP4 -7271.0
ZNF667 -7266.0
FBXO32 -7261.0
CDC25C -7260.0
CDC26 -7245.0
ELL -7225.0
CNOT2 -7216.0
ZNF135 -7208.0
NOP2 -7204.0
SUMO1 -7196.0
ZNF620 -7186.0
MAPKAPK5 -7178.0
BLM -7176.0
ZNF268 -7147.0
INTS13 -7146.0
SNAPC1 -7135.0
ZNF28 -7132.0
ZNF343 -7125.0
ING2 -7113.0
ZNF224 -7108.0
MTA2 -7100.0
TFDP2 -7095.0
ZNF419 -7093.0
ZNF227 -7085.0
ZNF430 -7080.0
TXNIP -7065.0
ZNF460 -7040.0
GATAD2B -7010.0
IGFBP3 -7002.0
PSMB2 -7000.0
THRA -6996.0
PSMB9 -6985.0
PSMD9 -6972.0
ZNF517 -6969.0
SETD1A -6967.0
TFAP2C -6954.0
MLLT1 -6919.0
ZNF354A -6914.0
L3MBTL2 -6904.0
POLR2H -6881.0
ZNF777 -6870.0
ZNF200 -6838.0
SRSF6 -6815.0
ZNF684 -6807.0
SOCS4 -6784.0
RYBP -6779.0
PHF20 -6767.0
ZNF454 -6755.0
TNFRSF18 -6753.0
ZNF521 -6741.0
CBX8 -6705.0
ZFP28 -6692.0
MED10 -6685.0
TAF15 -6684.0
CCND2 -6682.0
TAF2 -6681.0
SKP1 -6672.0
NPAS4 -6667.0
ZNF764 -6644.0
NPPA -6636.0
ZNF551 -6629.0
JMY -6626.0
NR3C1 -6622.0
DHX38 -6598.0
GAD1 -6578.0
ZNF543 -6573.0
PRKAG1 -6548.0
LMO2 -6539.0
CCNA2 -6534.0
ZNF45 -6511.0
PCGF2 -6508.0
INTS11 -6495.0
SMARCC2 -6480.0
ZNF738 -6470.0
RPAP2 -6463.0
RRM2 -6459.0
SIRT1 -6458.0
ZNF679 -6455.0
INTS10 -6444.0
CASC3 -6442.0
H2BC1 -6434.0
DEK -6397.0
CDKN1B -6381.0
ZNF253 -6380.0
COL1A2 -6369.0
NR3C2 -6368.0
YES1 -6326.0
ANAPC5 -6314.0
ZNF197 -6311.0
AKT2 -6287.0
KMT2A -6224.0
GTF2E1 -6214.0
ZNF583 -6169.0
TFAP2D -6161.0
TP63 -6146.0
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CEBPB -6129.0
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ZNF565 -6031.0
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ZNF529 -6009.0
CITED2 -5996.0
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ZNF773 -5904.0
PSMD13 -5903.0
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ZNF606 -5868.0
CDKN2A -5841.0
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E2F7 -5830.0
MGA -5775.0
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DPY30 -5759.0
ZNF559 -5738.0
ZNF285 -5730.0
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ZNF143 -5629.0
ZNF189 -5624.0
LSM11 -5620.0
SOD2 -5618.0
CRADD -5612.0
GPAM -5596.0
SRSF1 -5591.0
HNF4G -5589.0
APAF1 -5581.0
CDK13 -5577.0
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ABL1 -5559.0
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CCNE1 -5513.0
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PML -5486.0
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AUTS2 -5467.0
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ZNF282 -5456.0
ZNF425 -5440.0
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H2BC8 -5414.0
PRMT6 -5405.0
H3C4 -5404.0
ZNF12 -5397.0
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PCF11 -5367.0
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ZNF547 -5336.0
THOC1 -5330.0
GAMT -5319.0
NR2C1 -5305.0
ZNF441 -5284.0
CDK7 -5280.0
FANCI -5274.0
CASP1 -5264.0
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CRH -5220.0
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CTSK -5203.0
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ZNF548 -5187.0
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ZNF496 -5183.0
ZNF211 -5180.0
RRAGC -5175.0
PBRM1 -5162.0
NELFE -5152.0
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PSMA2 -5113.0
ITGAL -5111.0
CBX6 -5107.0
PSMD8 -5084.0
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RORB -5051.0
DGCR8 -5036.0
TOPBP1 -5020.0
GPI -5012.0
TFDP1 -5000.0
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ZNF184 -4933.0
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RNF2 -4904.0
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TTC5 -4896.0
FBXW7 -4860.0
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ZNF567 -4834.0
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ZNF337 -4773.0
GRIA2 -4755.0
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ZNF700 -4715.0
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JUNB -4687.0
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PDPK1 -4559.0
ZNF317 -4555.0
FANCC -4553.0
ZNF79 -4547.0
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ZNF875 -4462.0
MED17 -4459.0
ZNF660 -4425.0
ZNF17 -4424.0
PARP1 -4415.0
TBL1XR1 -4414.0
IWS1 -4404.0
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NELFCD -4386.0
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CLP1 -4376.0
ZNF619 -4371.0
RMI1 -4357.0
KDM5B -4355.0
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ZNF140 -4327.0
TJP1 -4314.0
ZFP69 -4308.0
HIVEP3 -4295.0
RBPJ -4269.0
INTS7 -4267.0
ARID1A -4245.0
SATB2 -4242.0
RBBP8 -4231.0
WRN -4227.0
GLS2 -4207.0
ZNF256 -4184.0
CYCS -4168.0
ZNF445 -4160.0
ZNF195 -4153.0
SNRPD3 -4100.0
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SMYD2 -4076.0
H2BC11 -4063.0
MED15 -4062.0
WDR5 -4056.0
CDC27 -4048.0
RBX1 -4039.0
CCNC -4022.0
PSMB3 -4011.0
RABGGTB -3971.0
ZNF33A -3947.0
POLR2G -3937.0
ZIM3 -3910.0
COX5B -3858.0
PPP2R1B -3830.0
ZNF254 -3825.0
RHEB -3824.0
PSME4 -3807.0
ZNF669 -3797.0
ZNF302 -3779.0
MLH1 -3770.0
POLR2B -3768.0
CBX4 -3688.0
ZNF714 -3675.0
NFYB -3674.0
E2F1 -3673.0
ZKSCAN5 -3657.0
ZNF540 -3629.0
PPARD -3617.0
GLS -3609.0
ANAPC2 -3595.0
TAF5 -3594.0
BRD2 -3576.0
H4C13 -3564.0
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RORA -3515.0
ZNF775 -3514.0
ZNF678 -3489.0
TAF11 -3452.0
ESRRA -3445.0
CHD3 -3438.0
PPARGC1A -3425.0
XPO1 -3414.0
MSX2 -3403.0
DDIT4 -3385.0
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ZNF708 -3313.0
NRBP1 -3299.0
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CNOT4 -3192.0
ZSCAN25 -3169.0
GSR -3160.0
MAPK1 -3156.0
CCNG1 -3154.0
ZNF568 -3146.0
ZNF706 -3127.0
PSMB1 -3117.0
PRKAB2 -3104.0
TOP3A -3093.0
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AGO3 -3073.0
KRBOX5 -3066.0
EPC1 -3053.0
ZFP90 -3046.0
SRSF3 -3037.0
ZNF689 -3026.0
PHC2 -3014.0
TAF6 -3011.0
RARG -2993.0
CUL1 -2987.0
ZNF324B -2985.0
JUN -2945.0
PAPOLA -2927.0
CASP2 -2919.0
CDK5 -2911.0
SLBP -2909.0
EED -2898.0
RNF111 -2896.0
TNFRSF10B -2888.0
ZNF668 -2850.0
KMT2E -2841.0
NOTCH1 -2808.0
YEATS4 -2805.0
BRD7 -2802.0
FOXO1 -2771.0
GTF2F2 -2764.0
PSMA7 -2759.0
ZNF225 -2754.0
ZKSCAN1 -2749.0
TAF4 -2733.0
HDAC3 -2723.0
MDM4 -2718.0
ZNF571 -2701.0
MAPKAP1 -2680.0
SESN2 -2675.0
ATM -2668.0
ZNF804B -2658.0
GSK3B -2656.0
TAF8 -2654.0
SMARCB1 -2643.0
E2F8 -2632.0
THBS1 -2605.0
ZNF461 -2560.0
SOX2 -2549.0
PSMF1 -2512.0
EZH2 -2496.0
PABPN1 -2472.0
INTS1 -2461.0
NCBP2 -2442.0
H4C2 -2432.0
CARM1 -2380.0
PERP -2289.0
PPP2R1A -2279.0
SYMPK -2275.0
HDAC7 -2273.0
AKT1 -2241.0
EHMT2 -2233.0
SPP1 -2232.0
MAML2 -2216.0
ZNF3 -2167.0
PIDD1 -2166.0
LEO1 -2164.0
CREB1 -2161.0
ZNF234 -2144.0
NR1H3 -2138.0
CAT -2137.0
ZNF354C -2134.0
ELOC -2118.0
SKIL -2113.0
SMAD7 -2103.0
EAF1 -2078.0
ZNF287 -2077.0
SRSF2 -2063.0
ZNF740 -2046.0
RBBP5 -2037.0
SNAPC4 -2029.0
COX7C -2020.0
ATXN3 -2018.0
RPA1 -2002.0
FANCD2 -1968.0
TRPC3 -1948.0
NFYC -1931.0
ZNF248 -1926.0
ZNF141 -1920.0
TSC2 -1891.0
ZNF510 -1887.0
H2AZ2 -1872.0
LEF1 -1871.0
ANAPC11 -1849.0
RFC5 -1846.0
PSMC1 -1839.0
INTS3 -1822.0
PSMA6 -1800.0
ZNF490 -1791.0
ZNF641 -1747.0
TPX2 -1745.0
RARA -1743.0
RHNO1 -1742.0
POLR2I -1736.0
STUB1 -1727.0
BDNF -1710.0
SNAPC3 -1703.0
WWOX -1696.0
IL2RA -1680.0
U2AF2 -1675.0
RBL1 -1654.0
CDKN1A -1607.0
ZNF681 -1606.0
CREBBP -1603.0
ZFPM1 -1594.0
CR1 -1589.0
TP53INP1 -1587.0
ZNF605 -1562.0
ZNF691 -1553.0
E2F4 -1544.0
ZNF729 -1479.0
ZNF311 -1456.0
CHD4 -1434.0
GTF2A1 -1415.0
TFAP2A -1408.0
ZNF747 -1373.0
NDRG1 -1371.0
SNRPE -1363.0
ZNF564 -1351.0
ATAD2 -1328.0
PIP4K2B -1322.0
ZNF701 -1312.0
POLR2A -1290.0
ZNF554 -1285.0
TSC1 -1235.0
LDB1 -1228.0
THOC6 -1219.0
SGK1 -1173.0
ING5 -1169.0
STK11 -1167.0
ZNF566 -1125.0
COX16 -1117.0
LBR -1114.0
DNA2 -1113.0
H2AC8 -1109.0
SMARCA4 -1103.0
ZNF680 -1097.0
TAF13 -1085.0
ICE1 -1041.0
ZNF552 -1036.0
OPRM1 -1005.0
SUPT5H -997.0
SOX9 -990.0
ZNF215 -971.0
SRSF7 -970.0
H2AJ -963.0
CCNA1 -948.0
PRKAA2 -936.0
CBX3 -932.0
TGIF1 -904.0
FOS -894.0
ZNF180 -892.0
FURIN -867.0
CBX2 -849.0
AIFM2 -835.0
CTR9 -832.0
PSMD1 -818.0
YWHAE -811.0
GTF2H5 -806.0
SARNP -780.0
MYC -745.0
RING1 -740.0
RPRD1B -730.0
SURF1 -695.0
CALM1 -694.0
ZNF786 -673.0
UBB -665.0
ZNF616 -663.0
PSMA4 -648.0
COX6C -638.0
PPP2R5C -627.0
ZNF25 -610.0
MED16 -585.0
RICTOR -564.0
SETD1B -490.0
NFKB1 -487.0
TBP -483.0
RARB -472.0
ZNF546 -455.0
SRSF4 -453.0
ZNF500 -446.0
TNRC6A -436.0
ZNF230 -433.0
BMP2 -360.0
SCMH1 -327.0
PGR -310.0
RAD17 -303.0
ANAPC4 -298.0
PPP2CB -279.0
BMAL1 -271.0
ZFP2 -234.0
ZNF688 -216.0
NR1H2 -214.0
ZNF771 -212.0
ATR -207.0
ZNF266 -206.0
PIP4P1 -164.0
MEF2C -155.0
RPS27A -126.0
ZNF446 -113.0
H4C12 -107.0
ZNF550 -105.0
RAD1 -102.0
ZNF664 -89.0
ZNF304 -82.0
PPP2CA -76.0
ZNF484 -57.0
MLST8 -52.0
BARD1 -51.0
SESN1 -50.0
NFATC2 -27.0
TEAD1 2.0
PRKCB 3.0
CAMK2D 13.0
SNW1 45.0
AURKB 55.0
TAF9 76.0
CNOT8 131.0
MDM2 136.0
ZNF222 142.0
ZNF169 150.0
ZNF716 156.0
GTF2H4 183.0
POLR2C 198.0
AGO2 199.0
TGIF2 248.0
NFYA 250.0
NOC2L 256.0
USP7 268.0
KMT2D 302.0
RAD9B 312.0
TBX5 314.0
H4C1 323.0
COX6A1 341.0
ZNF274 345.0
YBX1 363.0
ELF2 371.0
FYTTD1 374.0
AGO1 376.0
NR1D2 398.0
BCL2L11 400.0
ZNF10 401.0
ZNF791 419.0
KCTD6 430.0
ZNF471 438.0
RABGGTA 458.0
YAP1 465.0
TXNRD1 473.0
BANP 480.0
ALYREF 481.0
MED23 485.0
ZNF721 492.0
POLR2E 503.0
INTS2 531.0
ZFP69B 540.0
ESR1 559.0
SMURF1 562.0
NELFA 565.0
ZNF615 567.0
UBE2I 578.0
MED20 583.0
TGFB1 602.0
YWHAB 626.0
ZKSCAN3 675.0
PINK1 676.0
CTNNB1 682.0
H4C8 685.0
COX14 690.0
RXRA 721.0
CCND3 726.0
ZNF570 736.0
DDX39B 742.0
MED4 747.0
ZNF782 777.0
ZNF223 826.0
SMARCA2 828.0
H2BC17 842.0
PPARG 855.0
H2AX 876.0
CHEK2 921.0
RNU11 927.0
GTF2F1 936.0
PPM1A 965.0
GAD2 967.0
ERBB2 979.0
SNRPG 982.0
AFF4 987.0
PSMD11 1023.0
HEY1 1041.0
ZNF214 1058.0
MAML3 1071.0
ZNF692 1076.0
ACTL6A 1091.0
TNKS1BP1 1103.0
SRRT 1110.0
MED7 1116.0
TWIST1 1122.0
RSPO3 1145.0
GRIN2B 1149.0
CPSF4 1150.0
CNOT7 1183.0
RPA3 1184.0
MTOR 1189.0
ZNF611 1202.0
AKT3 1209.0
BRIP1 1255.0
CDK9 1265.0
PSMB4 1285.0
ZNF273 1289.0
CDC73 1290.0
ZNF212 1302.0
PSMA5 1304.0
RBL2 1308.0
TGFA 1315.0
ZIK1 1319.0
KAT2A 1331.0
TNFRSF10D 1364.0
ZNF704 1382.0
CCNT1 1385.0
ZNF114 1404.0
CAMK2G 1409.0
GRIN2A 1417.0
ZNF37A 1482.0
ESRRB 1512.0
ELOA2 1535.0
ZNF561 1545.0
CDK4 1550.0
SUPT6H 1565.0
DAXX 1573.0
YWHAH 1579.0
PSMC4 1596.0
ZNF613 1615.0
SKI 1638.0
HIPK2 1642.0
ZNF133 1680.0
ESR2 1685.0
CSTF3 1711.0
PHC3 1727.0
PRKAG2 1729.0
H3C11 1739.0
MED27 1751.0
PPARA 1763.0
ITGA4 1798.0
ZNF710 1804.0
ZNF586 1872.0
NR2F1 1873.0
HIPK1 1879.0
ZNF558 1883.0
ZNF136 1907.0
ZNF675 1925.0
ZNF250 1943.0
SSU72 1960.0
TCF3 1961.0
RFC2 1966.0
ZNF544 2021.0
SKIC8 2035.0
ZNF707 2040.0
ZNF774 2048.0
PSME2 2084.0
PF4 2093.0
ZNF483 2101.0
RAD51D 2111.0
DLL1 2131.0
ZNF573 2166.0
NR1H4 2175.0
ZNF71 2216.0
CSTF2T 2262.0
TFAP2B 2263.0
NUDT21 2268.0
ZNF112 2278.0
ITGA5 2279.0
BIRC5 2299.0
CPSF3 2301.0
ZNF792 2307.0
RPA2 2309.0
LGALS3 2320.0
PRKAB1 2331.0
CHEK1 2332.0
ZNF2 2335.0
ZNF436 2365.0
POLR2D 2370.0
ZNF727 2392.0
ZNF569 2417.0
TAF4B 2428.0
H3C10 2461.0
BRPF3 2474.0
H4C5 2528.0
ZNF394 2547.0
ELL3 2589.0
RNU4ATAC 2617.0
RRAGD 2628.0
DLX6 2670.0
BCL6 2676.0
UBE2D1 2677.0
DDIT3 2702.0
ZNF354B 2740.0
EIF4A3 2759.0
PRKACA 2782.0
GATAD2A 2784.0
PSMD12 2806.0
ZNF213 2883.0
ZNF625 2886.0
TAF12 2897.0
ZNF713 2912.0
ANAPC1 2923.0
ZNF562 2928.0
INTS12 2930.0
ZNF670 2948.0
BCL2L14 2973.0
ZNF582 2978.0
INTS5 2990.0
MDC1 2996.0
ZNF485 3018.0
YWHAQ 3040.0
ZNF610 3043.0
CAV1 3046.0
ZNF585B 3051.0
HDAC4 3070.0
AXIN1 3098.0
SERPINB13 3166.0
EHMT1 3168.0
POLR2F 3184.0
TNRC6C 3185.0
RRAGA 3202.0
FIP1L1 3206.0
PMAIP1 3208.0
NABP2 3227.0
ZNF732 3267.0
ZNF74 3271.0
NR1D1 3280.0
CCND1 3284.0
ATF2 3306.0
SMARCC1 3307.0
MEN1 3390.0
ZNF709 3398.0
ZKSCAN7 3437.0
EGFR 3462.0
RPTOR 3471.0
PRKCQ 3513.0
TACO1 3550.0
DDX39A 3574.0
NR5A2 3584.0
CSNK2A1 3638.0
SIRT3 3651.0
CENPJ 3667.0
TNFRSF10A 3673.0
POLR2J 3674.0
PSMD14 3679.0
TEAD3 3692.0
ZFHX3 3697.0
PRMT5 3698.0
RBFOX3 3711.0
H3C2 3733.0
NR6A1 3734.0
ZNF493 3759.0
NCOR1 3766.0
LRPPRC 3771.0
ZNF470 3779.0
THRB 3789.0
GLI3 3794.0
VEGFA 3867.0
ZNF26 3922.0
KCTD1 3968.0
CHTOP 3988.0
CDKN2B 4021.0
TRIM28 4029.0
RNPS1 4053.0
ZNF696 4093.0
H4C4 4097.0
ZNF235 4106.0
PPARGC1B 4140.0
NEDD4L 4151.0
ZNF761 4180.0
SMAD2 4200.0
MIR137 4242.0
CCNB1 4274.0
BBC3 4285.0
ZNF793 4287.0
NLRC4 4294.0
ZNF431 4300.0
TCF7L2 4305.0
GTF2E2 4313.0
TWIST2 4349.0
TAF7 4352.0
PSMB6 4375.0
ZNF20 4382.0
H2AZ1 4397.0
KCTD15 4441.0
CCNK 4453.0
ZNF267 4504.0
ZNF14 4521.0
ZNF320 4524.0
TIGAR 4549.0
ZNF770 4575.0
ABCA6 4576.0
WDR33 4577.0
MAPK11 4578.0
REST 4619.0
PIP4K2A 4624.0
PTPN1 4690.0
ZNF486 4696.0
IQSEC3 4700.0
PPP1R13B 4709.0
MET 4724.0
RXRG 4749.0
CDC7 4757.0
ZNF99 4793.0
ZNF347 4799.0
MYL9 4856.0
ZNF726 4859.0
H4C16 4865.0
KRBA1 4897.0
ZNF324 4912.0
DLX5 4920.0
PRDM1 4922.0
CDK1 4923.0
SNRPF 4945.0
ZNF718 4966.0
PTPN4 4983.0
ZNF665 5015.0
ZNF257 5025.0
LAMTOR5 5050.0
THOC3 5094.0
NKX3-2 5101.0
ACTL6B 5107.0
SMAD1 5151.0
ZNF385A 5162.0
RNMT 5190.0
NR1I2 5191.0
ZNF101 5225.0
RAD50 5232.0
TRIAP1 5276.0
DYRK2 5284.0
ZNF555 5328.0
ZNF506 5332.0
ZNF776 5333.0
H4C6 5430.0
BTG1 5450.0
NRBF2 5466.0
RET 5487.0
NOTCH2 5490.0
FASLG 5501.0
CDK5R1 5516.0
MED26 5549.0
SMURF2 5581.0
NKX2-5 5593.0
IHH 5594.0
WWTR1 5613.0
ZNF473 5628.0
SEM1 5631.0
ZNF662 5634.0
ZNF595 5653.0
ZNF839 5655.0
TEAD4 5696.0
SUPT4H1 5721.0
GPRIN1 5736.0
TP53 5757.0
PCBP4 5764.0
ZNF556 5765.0
ZNF468 5769.0
BLK 5838.0
PLK2 5860.0
JAG1 5861.0
LMO1 5962.0
TCEA1 6002.0
SSRP1 6003.0
PPP1R13L 6007.0
PHC1 6131.0
BID 6138.0
ANAPC15 6148.0
PSMD4 6169.0
SMAD6 6174.0
CGA 6197.0
COX5A 6246.0
ZNF154 6272.0
UBA52 6282.0
ZNF18 6295.0
SERPINE1 6311.0
PIP4K2C 6327.0
PTPN11 6400.0
KLF4 6441.0
CTSV 6447.0
IFNG 6483.0
ZNF697 6484.0
POU2F2 6485.0
ZNF626 6495.0
TEAD2 6512.0
OCLN 6561.0
ZNF799 6582.0
BGLAP 6602.0
CITED4 6605.0
RUNX3 6614.0
NOTCH4 6617.0
PAX5 6665.0
NR2E3 6670.0
MYBL2 6688.0
ZNF528 6764.0
ZNF607 6768.0
PSMD5 6795.0
GATA4 6866.0
NUAK1 6950.0
RELA 6961.0
NR5A1 6978.0
ZNF205 7005.0
CAMK2B 7010.0
PLXNA4 7036.0
PRDM7 7037.0
PRELID3A 7068.0
ZNF34 7086.0
SLC2A3 7140.0
NR2F6 7146.0
APOE 7188.0
CTLA4 7210.0
NOTCH3 7250.0
RGCC 7280.0
ZNF442 7304.0
AGRP 7329.0
TP73 7334.0
ZNF736 7375.0
G6PC1 7407.0
ZNF208 7415.0
COX8A 7527.0
MOBP 7534.0
TCF7 7537.0
ZNF286A 7615.0
ZNF682 7618.0
GLI2 7698.0
ZKSCAN4 7715.0
NR2E1 7738.0
ZNF334 7783.0
CTSL 7791.0
NPY 7862.0
TP53AIP1 7872.0
SRC 7873.0
CCN2 7892.0
ITGA2B 7936.0
SP7 8070.0
ZNF160 8102.0
TFAP2E 8167.0
USP2 8213.0
VENTX 8299.0
ZNF492 8322.0
ZNF596 8391.0
KCNIP3 8417.0
ZNF772 8445.0
ZNF19 8496.0
KIT 8522.0
IGFBP1 8706.0
FOXO6 8738.0
HDAC5 8742.0
TRIM63 8750.0
UBE2C 8787.0
TCF7L1 8828.0
STEAP3 8834.0
ZNF432 8872.0
GCK 8890.0
PCK1 8906.0
SMARCD3 8913.0
HNF4A 8930.0
ARNT2 8944.0
GPX2 8949.0
CSF1R 8955.0
KMT2B 9075.0
POMC 9122.0
ZNF415 9124.0
GEM 9168.0
ZNF730 9215.0
VDR 9296.0
BTG2 9300.0
PVALB 9326.0
ZNF519 9357.0
CSF2 9358.0
INS 9369.0
PSMB11 9506.0
CLDN5 9508.0
RETN 9509.0
RORC 9599.0
PRKAG3 9613.0
TNFRSF10C 9624.0
NR4A1 9696.0
COL1A1 9733.0
CAMK2A 9899.0
NR0B2 9930.0
NR2C2AP 9965.0
IL2 9975.0
ZNF233 10113.0
NR1I3 10215.0
SFN 10291.0
ZNF860 10440.0
UCMA 10513.0
CGB5 10593.5


REACTOME_CELL_CYCLE

REACTOME_CELL_CYCLE
190
set REACTOME_CELL_CYCLE
setSize 666
pANOVA 1.19e-28
s.dist -0.252
p.adjustANOVA 6.54e-26



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
PSMB7 -10651.0
PSMC6 -10621.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
ENSA -10263.0
H2BC12 -10245.0
DSN1 -10243.0
LIN52 -10236.0
CNTRL -10228.0
KIF2B -10210.0
PSMD2 -10209.0
H2AC20 -10208.0
BRCA1 -10206.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
PSMB7 -10651.0
PSMC6 -10621.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
ENSA -10263.0
H2BC12 -10245.0
DSN1 -10243.0
LIN52 -10236.0
CNTRL -10228.0
KIF2B -10210.0
PSMD2 -10209.0
H2AC20 -10208.0
BRCA1 -10206.0
H2BC15 -10189.0
CHTF18 -10162.0
FZR1 -10150.0
E2F6 -10093.0
PSMC2 -10087.0
RB1 -10080.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
SET -10005.0
CSNK2A2 -9986.0
CEP41 -9984.0
MCM5 -9953.0
PRIM2 -9944.0
LIG1 -9941.0
SYCP1 -9834.0
PSMA3 -9831.0
SUN2 -9821.0
CTDNEP1 -9802.0
TUBA1A -9776.0
RAD21 -9775.0
TUBA3E -9762.0
NCAPH2 -9726.0
ODF2 -9708.0
CDK6 -9698.0
ORC4 -9685.0
EP300 -9652.0
CCNE2 -9649.0
NCAPG -9638.0
PSMB8 -9616.0
PMF1 -9524.0
TK1 -9520.0
CCNB2 -9510.0
HUS1 -9493.0
PSME1 -9420.0
KIF18A -9410.0
CLASP2 -9395.0
TNPO1 -9369.0
H2BC26 -9346.0
PSMC5 -9310.0
NUP37 -9289.0
H2BC4 -9285.0
E2F5 -9245.0
YWHAZ -9228.0
BLZF1 -9154.0
RNF8 -9099.0
CSNK1D -9073.0
NME7 -9070.0
ANAPC16 -9057.0
PSMA8 -9037.0
ANKRD28 -9030.0
H2BC9 -9020.5
H3C7 -9020.5
CHMP4B -9016.0
PRIM1 -8994.0
CENPM -8958.0
KPNB1 -8945.0
DYNLL1 -8928.0
SSNA1 -8918.0
CDC14A -8886.0
TUBA3C -8877.0
NUP50 -8870.0
RAB2A -8861.0
VPS4A -8856.0
SYNE2 -8833.0
TEN1 -8771.0
CDC23 -8726.0
VRK2 -8725.0
CEP135 -8723.0
EXO1 -8718.0
POM121 -8700.0
RAB1B -8678.0
CDKN2C -8656.0
CENPH -8650.0
PSME3 -8645.0
SGO2 -8632.0
H2BC3 -8572.0
CHMP4C -8524.0
PSMD3 -8488.0
CENPT -8464.0
H4C3 -8451.0
KIF2C -8448.0
H2AC6 -8428.0
DCTN2 -8416.0
BUB1B -8413.0
NDE1 -8382.0
NUP42 -8381.0
MAPRE1 -8365.0
CKS1B -8337.0
SHQ1 -8310.0
PCNA -8301.0
GOLGA2 -8279.0
UBC -8277.0
RMI2 -8269.0
UBE2V2 -8249.0
POLD3 -8233.0
H2BC10 -8174.0
GORASP2 -8167.0
TERF1 -8166.0
SEH1L -8137.0
NUP98 -8136.0
KAT5 -8114.0
ANAPC7 -8113.0
ACTR1A -8070.0
KMT5A -8065.0
PSMD6 -8047.0
RAD9A -8023.0
CCP110 -8007.0
NUP107 -7996.0
NHP2 -7974.0
LIN54 -7849.0
CDK2 -7826.0
RAB1A -7794.0
NPM1 -7766.0
CDK11A -7743.0
CSNK2B -7734.0
MRE11 -7695.0
MNAT1 -7673.0
H4C11 -7658.0
CDCA8 -7604.0
RFC3 -7597.0
FKBPL -7594.0
H2BC13 -7580.0
PSMB10 -7549.0
CCNH -7537.0
RAD51 -7507.0
LEMD3 -7493.0
H3C1 -7492.0
PSMD7 -7470.0
FEN1 -7452.0
CDC16 -7384.0
PSMB5 -7376.0
HERC2 -7359.0
CHMP6 -7353.0
NBN -7344.0
POLE4 -7340.0
H2BC5 -7339.0
YWHAG -7293.0
RBBP4 -7271.0
CDC25C -7260.0
FBXL18 -7252.0
CDC26 -7245.0
LYN -7229.0
CENPQ -7210.0
SUMO1 -7196.0
TUBA1B -7184.0
BLM -7176.0
NUDC -7128.0
RNF168 -7116.0
TFDP2 -7095.0
RFC1 -7068.0
DYNC1LI1 -7041.0
PCNT -7036.0
PSMB2 -7000.0
PCM1 -6988.0
PSMB9 -6985.0
PSMD9 -6972.0
CDKN1C -6952.0
HAUS2 -6907.0
NUP214 -6894.0
POLR2H -6881.0
PDS5B -6842.0
CDC25A -6793.0
HAUS8 -6782.0
PHF20 -6767.0
MCM8 -6756.0
SYCP3 -6711.0
BABAM1 -6706.0
CCND2 -6682.0
PPP1CB -6679.0
POLA2 -6677.0
SKP1 -6672.0
AKAP9 -6655.0
GINS3 -6647.0
SPC25 -6632.0
LCMT1 -6604.0
PLK4 -6565.0
CCNA2 -6534.0
TUBA1C -6503.0
PDS5A -6492.0
NUP160 -6475.0
SEC13 -6469.0
RRM2 -6459.0
NDEL1 -6443.0
H2BC1 -6434.0
CDKN1B -6381.0
POLD2 -6366.0
CLIP1 -6364.0
CC2D1B -6346.0
CEP43 -6341.0
ANAPC5 -6314.0
AKT2 -6287.0
PAFAH1B1 -6282.0
ESCO2 -6260.0
RAE1 -6238.0
ORC3 -6201.0
DYNC1LI2 -6196.0
PPP1R12B -6165.0
LMNB1 -6160.0
UBE2E1 -6123.0
KNTC1 -6122.0
WAPL -6116.0
PIAS4 -6095.0
PSMC3 -6093.0
GORASP1 -6022.0
POLR2L -5972.0
TUBAL3 -5968.0
ACD -5957.5
SKP2 -5945.0
HDAC1 -5913.0
PSMD13 -5903.0
ABRAXAS1 -5893.0
CHMP7 -5878.0
CEP152 -5873.0
CDKN2A -5841.0
UBE2S -5833.0
SYCP2 -5829.0
ZWILCH -5742.0
NUP155 -5740.0
MIS12 -5727.0
GINS2 -5683.0
KNL1 -5659.0
NEK7 -5636.0
COP1 -5635.0
POLR2K -5634.0
RFC4 -5573.0
ABL1 -5559.0
RSF1 -5545.0
H3-3B -5536.0
NUP88 -5526.0
CCNE1 -5513.0
MAX -5422.0
H2BC8 -5414.0
H3C4 -5404.0
H3-3A -5377.0
VRK1 -5349.0
RANGAP1 -5347.0
E2F3 -5327.0
DIDO1 -5289.0
PPP2R5A -5281.0
CDK7 -5280.0
MIS18A -5237.0
ZW10 -5219.0
ATRIP -5204.0
DMC1 -5153.0
TUBB -5144.0
PPP2R2D -5129.0
MIS18BP1 -5124.0
BUB1 -5121.0
PSMA2 -5113.0
PSMD8 -5084.0
SFI1 -5062.0
BANF1 -5058.0
CEP164 -5049.0
TOPBP1 -5020.0
DYNC1H1 -5010.0
TFDP1 -5000.0
CEP131 -4990.0
NSD2 -4972.0
HJURP -4969.0
NSL1 -4893.0
NCAPG2 -4857.0
BRCA2 -4816.0
AURKA -4806.0
DYNC1I2 -4740.0
MZT1 -4704.0
CENPE -4657.0
H2AC4 -4647.0
CENPF -4587.0
ORC2 -4586.0
PSMA1 -4584.0
H3C8 -4535.0
CEP192 -4534.0
FBXL7 -4532.0
MCM10 -4516.0
POLD4 -4479.0
NUP58 -4439.0
RAN -4434.0
IST1 -4390.0
PTTG1 -4379.0
RMI1 -4357.0
LIN9 -4346.0
CEP63 -4342.0
MSH5 -4326.0
SMC2 -4271.0
KIF23 -4251.0
RBBP8 -4231.0
WRN -4227.0
CENPA -4213.0
TUBGCP6 -4200.0
STAG1 -4121.0
H2BC11 -4063.0
CDC27 -4048.0
RBX1 -4039.0
GTSE1 -4035.0
INCENP -4030.0
PSMB3 -4011.0
SKA2 -3991.0
POLR2G -3937.0
NUP188 -3926.0
PPP2R1B -3830.0
NCAPH -3822.0
GAR1 -3815.0
PSME4 -3807.0
GINS1 -3795.0
PPME1 -3771.0
MLH1 -3770.0
POLR2B -3768.0
BORA -3758.0
ESPL1 -3747.0
DBF4 -3726.0
PPP2R5E -3697.0
E2F1 -3673.0
TP53BP1 -3633.0
PPP6C -3610.0
ANAPC2 -3595.0
SMC4 -3591.0
POLE -3565.0
H4C13 -3564.0
ANAPC10 -3558.0
CHTF8 -3541.0
FOXM1 -3522.0
KIF2A -3457.0
CNEP1R1 -3416.0
XPO1 -3414.0
DCTN1 -3378.0
SPO11 -3276.0
TUBGCP5 -3241.0
RCC1 -3204.0
POT1 -3175.0
MAPK1 -3156.0
PSMB1 -3117.0
TOP3A -3093.0
MAPK3 -3089.0
USO1 -3012.0
CUL1 -2987.0
SYNE1 -2977.0
KIF20A -2934.0
MND1 -2879.0
DHFR -2865.0
NEDD1 -2861.0
ORC1 -2801.0
MAD1L1 -2784.0
PSMA7 -2759.0
ALMS1 -2753.0
MDM4 -2718.0
MASTL -2711.0
ATM -2668.0
GSK3B -2656.0
SPAST -2591.0
CKAP5 -2548.0
HSPA2 -2545.0
PSMF1 -2512.0
HSP90AA1 -2504.0
CLSPN -2497.0
H4C2 -2432.0
JAK2 -2403.0
MCPH1 -2360.0
LPIN1 -2351.0
CHMP4A -2308.0
PPP2R1A -2279.0
AKT1 -2241.0
CDC6 -2240.0
CDC25B -2168.0
TERF2 -2059.0
RPA1 -2002.0
MLH3 -1961.0
HSP90AB1 -1956.0
CEP76 -1898.0
ITGB3BP -1875.0
H2AZ2 -1872.0
ANAPC11 -1849.0
RFC5 -1846.0
PSMC1 -1839.0
PSMA6 -1800.0
DCTN3 -1770.0
NUF2 -1758.0
TPX2 -1745.0
RHNO1 -1742.0
MAU2 -1738.0
POLR2I -1736.0
FBXW11 -1723.0
B9D2 -1720.0
RBL1 -1654.0
CDCA5 -1650.0
HAUS3 -1643.0
CDKN1A -1607.0
CENPO -1579.0
E2F4 -1544.0
AAAS -1523.0
TUBGCP3 -1474.0
AHCTF1 -1446.0
TUBG2 -1414.0
RUVBL1 -1380.0
GINS4 -1375.0
SPDL1 -1326.0
TPR -1291.0
POLR2A -1290.0
NIPBL -1289.0
CABLES1 -1276.0
CTC1 -1252.0
CENPC -1213.0
RANBP2 -1170.0
TUBB4B -1137.0
NEK9 -1121.0
LBR -1114.0
DNA2 -1113.0
H2AC8 -1109.0
TERF2IP -1096.0
NUMA1 -1031.0
H2AJ -963.0
CCNA1 -948.0
NUP153 -930.0
E2F2 -920.0
NUP93 -887.0
FBXO5 -853.0
PSMD1 -818.0
YWHAE -811.0
MCM6 -758.0
LIN37 -750.0
MYC -745.0
NDC80 -719.0
BTRC -717.0
PLK1 -706.0
CDT1 -686.0
MCM2 -674.0
DYRK1A -666.0
UBB -665.0
PSMA4 -648.0
SPC24 -642.0
PPP2R5C -627.0
NDC1 -624.0
PPP1R12A -597.0
CDK5RAP2 -576.0
NEK2 -559.0
HMMR -516.0
CEP78 -473.0
PHLDA1 -470.0
SMARCA5 -420.0
ORC6 -370.0
CEP250 -354.0
CHMP3 -318.0
RAD17 -303.0
ANAPC4 -298.0
CENPN -295.0
PPP2CB -279.0
DYNC1I1 -230.0
ATR -207.0
RTEL1 -180.0
HAUS1 -142.0
RPS27A -126.0
H4C12 -107.0
RAD1 -102.0
PPP2CA -76.0
BARD1 -51.0
DSCC1 -35.0
PRKCB 3.0
CLASP1 37.0
AURKB 55.0
NCAPD2 57.0
TOP2A 81.0
POLE3 87.0
MDM2 136.0
PPP2R2A 137.0
SYCE1 176.0
CENPP 177.0
POLR2C 198.0
CEP72 255.0
CEP290 296.0
TUBB2A 305.0
RAD9B 312.0
H4C1 323.0
POLE2 373.0
OIP5 402.0
ESCO1 490.0
PPP2R5D 498.0
NCAPD3 500.0
POLR2E 503.0
STN1 518.0
UBE2I 578.0
MCM3 586.0
WEE1 588.0
SKA1 603.0
CEP70 612.0
YWHAB 626.0
H4C8 685.0
CCND3 726.0
PRKCA 781.0
H2BC17 842.0
H2AX 876.0
REC8 897.0
CHEK2 921.0
CENPL 945.0
GMNN 1002.0
PSMD11 1023.0
TINF2 1072.0
EML4 1165.0
NUP43 1180.0
RPA3 1184.0
AKT3 1209.0
TYMS 1214.0
POLD1 1233.0
BRIP1 1255.0
SIRT2 1269.0
UBE2N 1276.0
PSMB4 1285.0
CEP57 1297.0
PSMA5 1304.0
RBL2 1308.0
TAOK1 1373.0
TUBGCP2 1377.0
BABAM2 1393.0
CDK11B 1412.0
MAD2L1 1519.0
MZT2B 1526.0
CDK4 1550.0
DAXX 1573.0
ZWINT 1577.0
YWHAH 1579.0
LEMD2 1581.0
SDCCAG8 1584.0
PSMC4 1596.0
CENPS 1636.0
PPP6R3 1643.0
CHMP2B 1663.0
PRDM9 1695.0
H3C11 1739.0
SMC3 1750.0
RUVBL2 1772.0
CENPK 1845.0
SUN1 1904.0
RFC2 1966.0
PSME2 2084.0
HAUS4 2087.0
ARPP19 2091.0
RPS27 2171.0
BUB3 2174.0
BIRC5 2299.0
RPA2 2309.0
CDC45 2313.0
CHEK1 2332.0
OPTN 2343.0
POLR2D 2370.0
MCM7 2427.0
NUP85 2430.0
H3C10 2461.0
H4C5 2528.0
MCM4 2571.0
TMPO 2666.0
UBE2D1 2677.0
TEX12 2688.0
TUBA3D 2717.0
AJUBA 2746.0
PRKACA 2782.0
NUP205 2803.0
PSMD12 2806.0
ANAPC1 2923.0
MDC1 2996.0
YWHAQ 3040.0
NUP133 3158.0
POLR2F 3184.0
PPP2R5B 3218.0
NUP54 3235.0
NUP210 3259.0
CCND1 3284.0
TUBG1 3295.0
LPIN2 3323.0
TUBB6 3395.0
CDC20 3609.0
CSNK2A1 3638.0
CENPJ 3667.0
POLR2J 3674.0
PSMD14 3679.0
ANKLE2 3712.0
PKMYT1 3727.0
H3C2 3733.0
UIMC1 3738.0
WRAP53 3970.0
NOP10 3980.0
CDKN2B 4021.0
STAG3 4050.0
H4C4 4097.0
RAD51C 4234.0
CCNB1 4274.0
PSMB6 4375.0
H2AZ1 4397.0
SGO1 4410.0
RCC2 4422.0
PPP1CC 4750.0
CDC7 4757.0
NUP35 4792.0
H4C16 4865.0
CDK1 4923.0
HAUS6 5041.0
CENPU 5042.0
TUBB1 5090.0
ORC5 5159.0
ZNF385A 5162.0
CSNK1E 5169.0
RAD50 5232.0
TERT 5349.0
CHMP2A 5400.0
H4C6 5430.0
NUP62 5471.0
RAB8A 5599.0
SEM1 5631.0
CENPW 5691.0
TP53 5757.0
PCBP4 5764.0
PSMC3IP 5799.0
TUBGCP4 5925.0
DYNLL2 5999.0
TUBA4B 6042.0
ANAPC15 6148.0
PSMD4 6169.0
MZT2A 6202.0
UBA52 6282.0
TEX15 6309.0
FKBP6 6331.0
MSH4 6365.0
TUBB4A 6369.0
HAUS5 6547.0
TUBA4A 6664.0
LPIN3 6687.0
MYBL2 6688.0
PSMD5 6795.0
TUBB3 6928.0
NINL 6964.0
H3-4 7087.0
PIF1 7214.0
PRKAR2B 7419.0
SMC1B 7623.0
SYCE2 7753.0
LMNA 7850.0
SRC 7873.0
TUBB2B 7929.0
TUBA8 8140.0
POM121C 8315.0
NEK6 8708.0
UBE2C 8787.0
PTK6 8932.0
SYCE3 9216.0
PSMB11 9506.0
TUBB8 9559.0
CDKN2D 9657.0
SFN 10291.0


REACTOME_CELL_CYCLE_MITOTIC

REACTOME_CELL_CYCLE_MITOTIC
1112
set REACTOME_CELL_CYCLE_MITOTIC
setSize 539
pANOVA 4.03e-27
s.dist -0.271
p.adjustANOVA 1.65e-24



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
PSMB7 -10651.0
PSMC6 -10621.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
ENSA -10263.0
H2BC12 -10245.0
DSN1 -10243.0
LIN52 -10236.0
CNTRL -10228.0
KIF2B -10210.0
PSMD2 -10209.0
H2AC20 -10208.0
H2BC15 -10189.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
PSMB7 -10651.0
PSMC6 -10621.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
ENSA -10263.0
H2BC12 -10245.0
DSN1 -10243.0
LIN52 -10236.0
CNTRL -10228.0
KIF2B -10210.0
PSMD2 -10209.0
H2AC20 -10208.0
H2BC15 -10189.0
FZR1 -10150.0
E2F6 -10093.0
PSMC2 -10087.0
RB1 -10080.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
SET -10005.0
CSNK2A2 -9986.0
CEP41 -9984.0
MCM5 -9953.0
PRIM2 -9944.0
LIG1 -9941.0
PSMA3 -9831.0
CTDNEP1 -9802.0
TUBA1A -9776.0
RAD21 -9775.0
TUBA3E -9762.0
NCAPH2 -9726.0
ODF2 -9708.0
CDK6 -9698.0
ORC4 -9685.0
EP300 -9652.0
CCNE2 -9649.0
NCAPG -9638.0
PSMB8 -9616.0
PMF1 -9524.0
TK1 -9520.0
CCNB2 -9510.0
PSME1 -9420.0
KIF18A -9410.0
CLASP2 -9395.0
TNPO1 -9369.0
H2BC26 -9346.0
PSMC5 -9310.0
NUP37 -9289.0
H2BC4 -9285.0
E2F5 -9245.0
BLZF1 -9154.0
CSNK1D -9073.0
NME7 -9070.0
ANAPC16 -9057.0
PSMA8 -9037.0
H2BC9 -9020.5
H3C7 -9020.5
CHMP4B -9016.0
PRIM1 -8994.0
CENPM -8958.0
KPNB1 -8945.0
DYNLL1 -8928.0
SSNA1 -8918.0
CDC14A -8886.0
TUBA3C -8877.0
NUP50 -8870.0
RAB2A -8861.0
VPS4A -8856.0
CDC23 -8726.0
VRK2 -8725.0
CEP135 -8723.0
POM121 -8700.0
RAB1B -8678.0
CDKN2C -8656.0
CENPH -8650.0
PSME3 -8645.0
SGO2 -8632.0
H2BC3 -8572.0
CHMP4C -8524.0
PSMD3 -8488.0
CENPT -8464.0
H4C3 -8451.0
KIF2C -8448.0
H2AC6 -8428.0
DCTN2 -8416.0
BUB1B -8413.0
NDE1 -8382.0
NUP42 -8381.0
MAPRE1 -8365.0
CKS1B -8337.0
PCNA -8301.0
GOLGA2 -8279.0
UBC -8277.0
POLD3 -8233.0
H2BC10 -8174.0
GORASP2 -8167.0
SEH1L -8137.0
NUP98 -8136.0
ANAPC7 -8113.0
ACTR1A -8070.0
KMT5A -8065.0
PSMD6 -8047.0
CCP110 -8007.0
NUP107 -7996.0
LIN54 -7849.0
CDK2 -7826.0
RAB1A -7794.0
CDK11A -7743.0
CSNK2B -7734.0
MNAT1 -7673.0
H4C11 -7658.0
CDCA8 -7604.0
RFC3 -7597.0
FKBPL -7594.0
H2BC13 -7580.0
PSMB10 -7549.0
CCNH -7537.0
LEMD3 -7493.0
H3C1 -7492.0
PSMD7 -7470.0
FEN1 -7452.0
CDC16 -7384.0
PSMB5 -7376.0
CHMP6 -7353.0
POLE4 -7340.0
H2BC5 -7339.0
YWHAG -7293.0
RBBP4 -7271.0
CDC25C -7260.0
FBXL18 -7252.0
CDC26 -7245.0
LYN -7229.0
CENPQ -7210.0
SUMO1 -7196.0
TUBA1B -7184.0
NUDC -7128.0
TFDP2 -7095.0
RFC1 -7068.0
DYNC1LI1 -7041.0
PCNT -7036.0
PSMB2 -7000.0
PCM1 -6988.0
PSMB9 -6985.0
PSMD9 -6972.0
CDKN1C -6952.0
HAUS2 -6907.0
NUP214 -6894.0
PDS5B -6842.0
CDC25A -6793.0
HAUS8 -6782.0
MCM8 -6756.0
CCND2 -6682.0
PPP1CB -6679.0
POLA2 -6677.0
SKP1 -6672.0
AKAP9 -6655.0
GINS3 -6647.0
SPC25 -6632.0
LCMT1 -6604.0
PLK4 -6565.0
CCNA2 -6534.0
TUBA1C -6503.0
PDS5A -6492.0
NUP160 -6475.0
SEC13 -6469.0
RRM2 -6459.0
NDEL1 -6443.0
H2BC1 -6434.0
CDKN1B -6381.0
POLD2 -6366.0
CLIP1 -6364.0
CC2D1B -6346.0
CEP43 -6341.0
ANAPC5 -6314.0
AKT2 -6287.0
PAFAH1B1 -6282.0
ESCO2 -6260.0
RAE1 -6238.0
ORC3 -6201.0
DYNC1LI2 -6196.0
PPP1R12B -6165.0
LMNB1 -6160.0
UBE2E1 -6123.0
KNTC1 -6122.0
WAPL -6116.0
PSMC3 -6093.0
GORASP1 -6022.0
TUBAL3 -5968.0
SKP2 -5945.0
HDAC1 -5913.0
PSMD13 -5903.0
CHMP7 -5878.0
CEP152 -5873.0
CDKN2A -5841.0
UBE2S -5833.0
ZWILCH -5742.0
NUP155 -5740.0
MIS12 -5727.0
GINS2 -5683.0
KNL1 -5659.0
NEK7 -5636.0
RFC4 -5573.0
ABL1 -5559.0
H3-3B -5536.0
NUP88 -5526.0
CCNE1 -5513.0
MAX -5422.0
H2BC8 -5414.0
H3C4 -5404.0
H3-3A -5377.0
VRK1 -5349.0
RANGAP1 -5347.0
E2F3 -5327.0
PPP2R5A -5281.0
CDK7 -5280.0
ZW10 -5219.0
TUBB -5144.0
PPP2R2D -5129.0
BUB1 -5121.0
PSMA2 -5113.0
PSMD8 -5084.0
SFI1 -5062.0
BANF1 -5058.0
CEP164 -5049.0
DYNC1H1 -5010.0
TFDP1 -5000.0
CEP131 -4990.0
NSL1 -4893.0
NCAPG2 -4857.0
AURKA -4806.0
DYNC1I2 -4740.0
MZT1 -4704.0
CENPE -4657.0
H2AC4 -4647.0
CENPF -4587.0
ORC2 -4586.0
PSMA1 -4584.0
H3C8 -4535.0
CEP192 -4534.0
FBXL7 -4532.0
MCM10 -4516.0
POLD4 -4479.0
NUP58 -4439.0
RAN -4434.0
IST1 -4390.0
PTTG1 -4379.0
LIN9 -4346.0
CEP63 -4342.0
SMC2 -4271.0
KIF23 -4251.0
CENPA -4213.0
TUBGCP6 -4200.0
STAG1 -4121.0
H2BC11 -4063.0
CDC27 -4048.0
RBX1 -4039.0
GTSE1 -4035.0
INCENP -4030.0
PSMB3 -4011.0
SKA2 -3991.0
NUP188 -3926.0
PPP2R1B -3830.0
NCAPH -3822.0
PSME4 -3807.0
GINS1 -3795.0
PPME1 -3771.0
BORA -3758.0
ESPL1 -3747.0
DBF4 -3726.0
PPP2R5E -3697.0
E2F1 -3673.0
ANAPC2 -3595.0
SMC4 -3591.0
POLE -3565.0
H4C13 -3564.0
ANAPC10 -3558.0
FOXM1 -3522.0
KIF2A -3457.0
CNEP1R1 -3416.0
XPO1 -3414.0
DCTN1 -3378.0
TUBGCP5 -3241.0
RCC1 -3204.0
MAPK1 -3156.0
PSMB1 -3117.0
MAPK3 -3089.0
USO1 -3012.0
CUL1 -2987.0
KIF20A -2934.0
DHFR -2865.0
NEDD1 -2861.0
ORC1 -2801.0
MAD1L1 -2784.0
PSMA7 -2759.0
ALMS1 -2753.0
MASTL -2711.0
GSK3B -2656.0
SPAST -2591.0
CKAP5 -2548.0
PSMF1 -2512.0
HSP90AA1 -2504.0
H4C2 -2432.0
JAK2 -2403.0
MCPH1 -2360.0
LPIN1 -2351.0
CHMP4A -2308.0
PPP2R1A -2279.0
AKT1 -2241.0
CDC6 -2240.0
CDC25B -2168.0
RPA1 -2002.0
HSP90AB1 -1956.0
CEP76 -1898.0
ITGB3BP -1875.0
H2AZ2 -1872.0
ANAPC11 -1849.0
RFC5 -1846.0
PSMC1 -1839.0
PSMA6 -1800.0
DCTN3 -1770.0
NUF2 -1758.0
TPX2 -1745.0
MAU2 -1738.0
FBXW11 -1723.0
B9D2 -1720.0
RBL1 -1654.0
CDCA5 -1650.0
HAUS3 -1643.0
CDKN1A -1607.0
CENPO -1579.0
E2F4 -1544.0
AAAS -1523.0
TUBGCP3 -1474.0
AHCTF1 -1446.0
TUBG2 -1414.0
GINS4 -1375.0
SPDL1 -1326.0
TPR -1291.0
NIPBL -1289.0
CABLES1 -1276.0
CENPC -1213.0
RANBP2 -1170.0
TUBB4B -1137.0
NEK9 -1121.0
LBR -1114.0
DNA2 -1113.0
H2AC8 -1109.0
NUMA1 -1031.0
H2AJ -963.0
CCNA1 -948.0
NUP153 -930.0
E2F2 -920.0
NUP93 -887.0
FBXO5 -853.0
PSMD1 -818.0
YWHAE -811.0
MCM6 -758.0
LIN37 -750.0
MYC -745.0
NDC80 -719.0
BTRC -717.0
PLK1 -706.0
CDT1 -686.0
MCM2 -674.0
DYRK1A -666.0
UBB -665.0
PSMA4 -648.0
SPC24 -642.0
PPP2R5C -627.0
NDC1 -624.0
PPP1R12A -597.0
CDK5RAP2 -576.0
NEK2 -559.0
HMMR -516.0
CEP78 -473.0
PHLDA1 -470.0
ORC6 -370.0
CEP250 -354.0
CHMP3 -318.0
ANAPC4 -298.0
CENPN -295.0
PPP2CB -279.0
DYNC1I1 -230.0
HAUS1 -142.0
RPS27A -126.0
H4C12 -107.0
PPP2CA -76.0
PRKCB 3.0
CLASP1 37.0
AURKB 55.0
NCAPD2 57.0
TOP2A 81.0
POLE3 87.0
PPP2R2A 137.0
CENPP 177.0
CEP72 255.0
CEP290 296.0
TUBB2A 305.0
H4C1 323.0
POLE2 373.0
ESCO1 490.0
PPP2R5D 498.0
NCAPD3 500.0
UBE2I 578.0
MCM3 586.0
WEE1 588.0
SKA1 603.0
CEP70 612.0
H4C8 685.0
CCND3 726.0
PRKCA 781.0
H2BC17 842.0
H2AX 876.0
CENPL 945.0
GMNN 1002.0
PSMD11 1023.0
EML4 1165.0
NUP43 1180.0
RPA3 1184.0
AKT3 1209.0
TYMS 1214.0
POLD1 1233.0
SIRT2 1269.0
PSMB4 1285.0
CEP57 1297.0
PSMA5 1304.0
RBL2 1308.0
TAOK1 1373.0
TUBGCP2 1377.0
CDK11B 1412.0
MAD2L1 1519.0
MZT2B 1526.0
CDK4 1550.0
ZWINT 1577.0
LEMD2 1581.0
SDCCAG8 1584.0
PSMC4 1596.0
CENPS 1636.0
CHMP2B 1663.0
H3C11 1739.0
SMC3 1750.0
CENPK 1845.0
RFC2 1966.0
PSME2 2084.0
HAUS4 2087.0
ARPP19 2091.0
RPS27 2171.0
BUB3 2174.0
BIRC5 2299.0
RPA2 2309.0
CDC45 2313.0
OPTN 2343.0
MCM7 2427.0
NUP85 2430.0
H3C10 2461.0
H4C5 2528.0
MCM4 2571.0
TMPO 2666.0
UBE2D1 2677.0
TUBA3D 2717.0
AJUBA 2746.0
PRKACA 2782.0
NUP205 2803.0
PSMD12 2806.0
ANAPC1 2923.0
NUP133 3158.0
PPP2R5B 3218.0
NUP54 3235.0
NUP210 3259.0
CCND1 3284.0
TUBG1 3295.0
LPIN2 3323.0
TUBB6 3395.0
CDC20 3609.0
CSNK2A1 3638.0
CENPJ 3667.0
PSMD14 3679.0
ANKLE2 3712.0
PKMYT1 3727.0
H3C2 3733.0
CDKN2B 4021.0
H4C4 4097.0
CCNB1 4274.0
PSMB6 4375.0
H2AZ1 4397.0
SGO1 4410.0
RCC2 4422.0
PPP1CC 4750.0
CDC7 4757.0
NUP35 4792.0
H4C16 4865.0
CDK1 4923.0
HAUS6 5041.0
CENPU 5042.0
TUBB1 5090.0
ORC5 5159.0
CSNK1E 5169.0
CHMP2A 5400.0
H4C6 5430.0
NUP62 5471.0
RAB8A 5599.0
SEM1 5631.0
TP53 5757.0
TUBGCP4 5925.0
DYNLL2 5999.0
TUBA4B 6042.0
ANAPC15 6148.0
PSMD4 6169.0
MZT2A 6202.0
UBA52 6282.0
TUBB4A 6369.0
HAUS5 6547.0
TUBA4A 6664.0
LPIN3 6687.0
MYBL2 6688.0
PSMD5 6795.0
TUBB3 6928.0
NINL 6964.0
H3-4 7087.0
PRKAR2B 7419.0
LMNA 7850.0
SRC 7873.0
TUBB2B 7929.0
TUBA8 8140.0
POM121C 8315.0
NEK6 8708.0
UBE2C 8787.0
PTK6 8932.0
PSMB11 9506.0
TUBB8 9559.0
CDKN2D 9657.0


REACTOME_M_PHASE

REACTOME_M_PHASE
1096
set REACTOME_M_PHASE
setSize 398
pANOVA 6.42e-20
s.dist -0.267
p.adjustANOVA 2.11e-17



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
PSMB7 -10651.0
PSMC6 -10621.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
ENSA -10263.0
H2BC12 -10245.0
DSN1 -10243.0
CNTRL -10228.0
KIF2B -10210.0
PSMD2 -10209.0
H2AC20 -10208.0
H2BC15 -10189.0
PSMC2 -10087.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
PSMB7 -10651.0
PSMC6 -10621.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
ENSA -10263.0
H2BC12 -10245.0
DSN1 -10243.0
CNTRL -10228.0
KIF2B -10210.0
PSMD2 -10209.0
H2AC20 -10208.0
H2BC15 -10189.0
PSMC2 -10087.0
RB1 -10080.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
SET -10005.0
CSNK2A2 -9986.0
CEP41 -9984.0
PSMA3 -9831.0
CTDNEP1 -9802.0
TUBA1A -9776.0
RAD21 -9775.0
TUBA3E -9762.0
NCAPH2 -9726.0
ODF2 -9708.0
NCAPG -9638.0
PSMB8 -9616.0
PMF1 -9524.0
CCNB2 -9510.0
PSME1 -9420.0
KIF18A -9410.0
CLASP2 -9395.0
TNPO1 -9369.0
H2BC26 -9346.0
PSMC5 -9310.0
NUP37 -9289.0
H2BC4 -9285.0
BLZF1 -9154.0
CSNK1D -9073.0
NME7 -9070.0
ANAPC16 -9057.0
PSMA8 -9037.0
H2BC9 -9020.5
H3C7 -9020.5
CHMP4B -9016.0
CENPM -8958.0
KPNB1 -8945.0
DYNLL1 -8928.0
SSNA1 -8918.0
TUBA3C -8877.0
NUP50 -8870.0
RAB2A -8861.0
VPS4A -8856.0
CDC23 -8726.0
VRK2 -8725.0
CEP135 -8723.0
POM121 -8700.0
RAB1B -8678.0
CENPH -8650.0
PSME3 -8645.0
SGO2 -8632.0
H2BC3 -8572.0
CHMP4C -8524.0
PSMD3 -8488.0
CENPT -8464.0
H4C3 -8451.0
KIF2C -8448.0
H2AC6 -8428.0
DCTN2 -8416.0
BUB1B -8413.0
NDE1 -8382.0
NUP42 -8381.0
MAPRE1 -8365.0
GOLGA2 -8279.0
UBC -8277.0
H2BC10 -8174.0
GORASP2 -8167.0
SEH1L -8137.0
NUP98 -8136.0
ANAPC7 -8113.0
ACTR1A -8070.0
KMT5A -8065.0
PSMD6 -8047.0
CCP110 -8007.0
NUP107 -7996.0
RAB1A -7794.0
CSNK2B -7734.0
H4C11 -7658.0
CDCA8 -7604.0
H2BC13 -7580.0
PSMB10 -7549.0
LEMD3 -7493.0
H3C1 -7492.0
PSMD7 -7470.0
CDC16 -7384.0
PSMB5 -7376.0
CHMP6 -7353.0
H2BC5 -7339.0
YWHAG -7293.0
CDC26 -7245.0
CENPQ -7210.0
SUMO1 -7196.0
TUBA1B -7184.0
NUDC -7128.0
DYNC1LI1 -7041.0
PCNT -7036.0
PSMB2 -7000.0
PCM1 -6988.0
PSMB9 -6985.0
PSMD9 -6972.0
HAUS2 -6907.0
NUP214 -6894.0
PDS5B -6842.0
HAUS8 -6782.0
AKAP9 -6655.0
SPC25 -6632.0
PLK4 -6565.0
TUBA1C -6503.0
PDS5A -6492.0
NUP160 -6475.0
SEC13 -6469.0
NDEL1 -6443.0
H2BC1 -6434.0
CLIP1 -6364.0
CC2D1B -6346.0
CEP43 -6341.0
ANAPC5 -6314.0
PAFAH1B1 -6282.0
RAE1 -6238.0
DYNC1LI2 -6196.0
LMNB1 -6160.0
UBE2E1 -6123.0
KNTC1 -6122.0
WAPL -6116.0
PSMC3 -6093.0
GORASP1 -6022.0
TUBAL3 -5968.0
PSMD13 -5903.0
CHMP7 -5878.0
CEP152 -5873.0
UBE2S -5833.0
ZWILCH -5742.0
NUP155 -5740.0
MIS12 -5727.0
KNL1 -5659.0
NEK7 -5636.0
H3-3B -5536.0
NUP88 -5526.0
H2BC8 -5414.0
H3C4 -5404.0
H3-3A -5377.0
VRK1 -5349.0
RANGAP1 -5347.0
PPP2R5A -5281.0
ZW10 -5219.0
TUBB -5144.0
PPP2R2D -5129.0
BUB1 -5121.0
PSMA2 -5113.0
PSMD8 -5084.0
SFI1 -5062.0
BANF1 -5058.0
CEP164 -5049.0
DYNC1H1 -5010.0
CEP131 -4990.0
NSL1 -4893.0
NCAPG2 -4857.0
DYNC1I2 -4740.0
MZT1 -4704.0
CENPE -4657.0
H2AC4 -4647.0
CENPF -4587.0
PSMA1 -4584.0
H3C8 -4535.0
CEP192 -4534.0
NUP58 -4439.0
RAN -4434.0
IST1 -4390.0
PTTG1 -4379.0
CEP63 -4342.0
SMC2 -4271.0
KIF23 -4251.0
CENPA -4213.0
TUBGCP6 -4200.0
STAG1 -4121.0
H2BC11 -4063.0
CDC27 -4048.0
INCENP -4030.0
PSMB3 -4011.0
SKA2 -3991.0
NUP188 -3926.0
PPP2R1B -3830.0
NCAPH -3822.0
PSME4 -3807.0
ESPL1 -3747.0
PPP2R5E -3697.0
ANAPC2 -3595.0
SMC4 -3591.0
H4C13 -3564.0
ANAPC10 -3558.0
KIF2A -3457.0
CNEP1R1 -3416.0
XPO1 -3414.0
DCTN1 -3378.0
TUBGCP5 -3241.0
RCC1 -3204.0
MAPK1 -3156.0
PSMB1 -3117.0
MAPK3 -3089.0
USO1 -3012.0
KIF20A -2934.0
NEDD1 -2861.0
MAD1L1 -2784.0
PSMA7 -2759.0
ALMS1 -2753.0
MASTL -2711.0
SPAST -2591.0
CKAP5 -2548.0
PSMF1 -2512.0
HSP90AA1 -2504.0
H4C2 -2432.0
MCPH1 -2360.0
LPIN1 -2351.0
CHMP4A -2308.0
PPP2R1A -2279.0
CEP76 -1898.0
ITGB3BP -1875.0
H2AZ2 -1872.0
ANAPC11 -1849.0
PSMC1 -1839.0
PSMA6 -1800.0
DCTN3 -1770.0
NUF2 -1758.0
MAU2 -1738.0
B9D2 -1720.0
CDCA5 -1650.0
HAUS3 -1643.0
CENPO -1579.0
AAAS -1523.0
TUBGCP3 -1474.0
AHCTF1 -1446.0
TUBG2 -1414.0
SPDL1 -1326.0
TPR -1291.0
NIPBL -1289.0
CENPC -1213.0
RANBP2 -1170.0
TUBB4B -1137.0
NEK9 -1121.0
LBR -1114.0
H2AC8 -1109.0
NUMA1 -1031.0
H2AJ -963.0
NUP153 -930.0
NUP93 -887.0
FBXO5 -853.0
PSMD1 -818.0
YWHAE -811.0
NDC80 -719.0
PLK1 -706.0
UBB -665.0
PSMA4 -648.0
SPC24 -642.0
PPP2R5C -627.0
NDC1 -624.0
CDK5RAP2 -576.0
NEK2 -559.0
CEP78 -473.0
CEP250 -354.0
CHMP3 -318.0
ANAPC4 -298.0
CENPN -295.0
PPP2CB -279.0
DYNC1I1 -230.0
HAUS1 -142.0
RPS27A -126.0
H4C12 -107.0
PPP2CA -76.0
PRKCB 3.0
CLASP1 37.0
AURKB 55.0
NCAPD2 57.0
PPP2R2A 137.0
CENPP 177.0
CEP72 255.0
CEP290 296.0
TUBB2A 305.0
H4C1 323.0
PPP2R5D 498.0
NCAPD3 500.0
UBE2I 578.0
SKA1 603.0
CEP70 612.0
H4C8 685.0
PRKCA 781.0
H2BC17 842.0
H2AX 876.0
CENPL 945.0
PSMD11 1023.0
EML4 1165.0
NUP43 1180.0
SIRT2 1269.0
PSMB4 1285.0
CEP57 1297.0
PSMA5 1304.0
TAOK1 1373.0
TUBGCP2 1377.0
MAD2L1 1519.0
MZT2B 1526.0
ZWINT 1577.0
LEMD2 1581.0
SDCCAG8 1584.0
PSMC4 1596.0
CENPS 1636.0
CHMP2B 1663.0
H3C11 1739.0
SMC3 1750.0
CENPK 1845.0
PSME2 2084.0
HAUS4 2087.0
ARPP19 2091.0
RPS27 2171.0
BUB3 2174.0
BIRC5 2299.0
NUP85 2430.0
H3C10 2461.0
H4C5 2528.0
TMPO 2666.0
UBE2D1 2677.0
TUBA3D 2717.0
PRKACA 2782.0
NUP205 2803.0
PSMD12 2806.0
ANAPC1 2923.0
NUP133 3158.0
PPP2R5B 3218.0
NUP54 3235.0
NUP210 3259.0
TUBG1 3295.0
LPIN2 3323.0
TUBB6 3395.0
CDC20 3609.0
CSNK2A1 3638.0
CENPJ 3667.0
PSMD14 3679.0
ANKLE2 3712.0
H3C2 3733.0
H4C4 4097.0
CCNB1 4274.0
PSMB6 4375.0
H2AZ1 4397.0
SGO1 4410.0
RCC2 4422.0
PPP1CC 4750.0
NUP35 4792.0
H4C16 4865.0
CDK1 4923.0
HAUS6 5041.0
CENPU 5042.0
TUBB1 5090.0
CSNK1E 5169.0
CHMP2A 5400.0
H4C6 5430.0
NUP62 5471.0
SEM1 5631.0
TUBGCP4 5925.0
DYNLL2 5999.0
TUBA4B 6042.0
ANAPC15 6148.0
PSMD4 6169.0
MZT2A 6202.0
UBA52 6282.0
TUBB4A 6369.0
HAUS5 6547.0
TUBA4A 6664.0
LPIN3 6687.0
PSMD5 6795.0
TUBB3 6928.0
NINL 6964.0
H3-4 7087.0
PRKAR2B 7419.0
LMNA 7850.0
TUBB2B 7929.0
TUBA8 8140.0
POM121C 8315.0
NEK6 8708.0
UBE2C 8787.0
PSMB11 9506.0
TUBB8 9559.0


REACTOME_CELLULAR_RESPONSES_TO_STIMULI

REACTOME_CELLULAR_RESPONSES_TO_STIMULI
1314
set REACTOME_CELLULAR_RESPONSES_TO_STIMULI
setSize 779
pANOVA 9.35e-20
s.dist -0.191
p.adjustANOVA 2.56e-17



Top enriched genes

Top 20 genes
GeneID Gene Rank
RLN1 -11249
H2BC14 -11029
RPL10L -11011
CALR -10983
H3C6 -10917
H3C12 -10877
SHC1 -10869
XBP1 -10837
H3C3 -10808
DNAJC3 -10775
ATP6V0E2 -10771
MIR24-2 -10766
H2AC14 -10727
PSMB7 -10651
RPL35A -10631
PSMC6 -10621
EIF2S2 -10570
CSRP1 -10556
BACH1 -10546
TXN -10530

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RLN1 -11249.0
H2BC14 -11029.0
RPL10L -11011.0
CALR -10983.0
H3C6 -10917.0
H3C12 -10877.0
SHC1 -10869.0
XBP1 -10837.0
H3C3 -10808.0
DNAJC3 -10775.0
ATP6V0E2 -10771.0
MIR24-2 -10766.0
H2AC14 -10727.0
PSMB7 -10651.0
RPL35A -10631.0
PSMC6 -10621.0
EIF2S2 -10570.0
CSRP1 -10556.0
BACH1 -10546.0
TXN -10530.0
RPL37A -10509.0
COX18 -10439.0
FKBP5 -10385.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
MOV10 -10287.0
H2BC12 -10245.0
PSMD2 -10209.0
H2AC20 -10208.0
BRCA1 -10206.0
H2BC15 -10189.0
RPS6KA1 -10164.0
FZR1 -10150.0
PSMC2 -10087.0
HSPA13 -10082.0
RB1 -10080.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
CSNK2A2 -9986.0
LAMTOR3 -9915.0
LIMD1 -9875.0
ELOB -9858.0
PSMA3 -9831.0
SERP1 -9807.0
TUBA1A -9776.0
SOD1 -9765.0
TUBA3E -9762.0
ATP6V1C1 -9707.0
CDK6 -9698.0
HSPA4 -9695.0
SP1 -9694.0
EP300 -9652.0
CCNE2 -9649.0
MAPK14 -9643.0
RPL11 -9622.0
PSMB8 -9616.0
MAP2K6 -9611.0
RPS5 -9536.0
IL6 -9492.0
DCTN4 -9461.0
PSME1 -9420.0
H2BC26 -9346.0
CAPZA3 -9318.0
PSMC5 -9310.0
NUP37 -9289.0
H2BC4 -9285.0
FNIP1 -9263.0
SLC46A1 -9256.0
EXOSC7 -9248.0
CRTC2 -9237.0
ATP6V1E1 -9236.0
SCO2 -9217.0
H1-2 -9191.0
SCO1 -9085.0
HSPA1A -9068.0
ANAPC16 -9057.0
RPS23 -9056.0
BAG1 -9048.0
PSMA8 -9037.0
H2BC9 -9020.5
H3C7 -9020.5
DYNLL1 -8928.0
LAMTOR2 -8879.0
TUBA3C -8877.0
RPL24 -8875.0
NUP50 -8870.0
CXCL8 -8858.0
ATP6V1A -8823.0
RPL32 -8790.0
BMI1 -8777.0
CDC23 -8726.0
KHSRP -8722.0
ATP6V0C -8715.0
POM121 -8700.0
DNAJA2 -8666.0
SIN3A -8665.0
CDKN2C -8656.0
KPTN -8655.0
ABCC1 -8646.0
PSME3 -8645.0
RPL4 -8640.0
HERPUD1 -8629.0
SUZ12 -8594.0
NCOA2 -8586.0
H2BC3 -8572.0
RPL23A -8537.0
PSMD3 -8488.0
ETS2 -8482.0
H4C3 -8451.0
COX7A2L -8438.0
H2AC6 -8428.0
DCTN2 -8416.0
LAMTOR4 -8388.0
PRDX3 -8384.0
NUP42 -8381.0
MIR24-1 -8349.0
UBC -8277.0
STAT3 -8252.0
KICS2 -8218.0
FAU -8194.0
H2BC10 -8174.0
TERF1 -8166.0
EIF2AK3 -8140.0
SEH1L -8137.0
NUP98 -8136.0
KAT5 -8114.0
ANAPC7 -8113.0
ACTR1A -8070.0
CREB3 -8064.0
KDM6B -8060.0
RPL23 -8055.0
PSMD6 -8047.0
RPL13 -8037.0
NUP107 -7996.0
CREB3L4 -7970.0
COX11 -7946.0
WIPI1 -7928.0
ITFG2 -7916.0
SEC31A -7903.0
DPP3 -7871.0
CDK2 -7826.0
EXOSC4 -7820.0
TKT -7816.0
UBXN7 -7752.0
CSNK2B -7734.0
SIN3B -7729.0
TNRC6B -7724.0
CXXC1 -7706.0
MRE11 -7695.0
MTF1 -7693.0
EEF1A1 -7671.0
H4C11 -7658.0
UBE2D3 -7616.0
ARNT -7593.0
H2BC13 -7580.0
AGO4 -7579.0
PSMB10 -7549.0
ATP6V1D -7494.0
H3C1 -7492.0
GSK3A -7471.0
PSMD7 -7470.0
HSP90B1 -7448.0
MAFG -7440.0
RPL7A -7402.0
CDC16 -7384.0
PSMB5 -7376.0
NBN -7344.0
H2BC5 -7339.0
EIF2S1 -7327.0
RPL35 -7326.0
RPL31 -7280.0
COX4I1 -7276.0
RBBP4 -7271.0
CDC26 -7245.0
PARN -7228.0
RPS26 -7213.0
MIOS -7195.0
USP46 -7192.0
TUBA1B -7184.0
MAPKAPK5 -7178.0
BAG4 -7162.0
CAPZA1 -7141.0
TFDP2 -7095.0
TXNIP -7065.0
ACTR10 -7043.0
DYNC1LI1 -7041.0
PSMB2 -7000.0
TPP1 -6989.0
PSMB9 -6985.0
PSMD9 -6972.0
FKBP4 -6928.0
H1-5 -6899.0
NUP214 -6894.0
VCP -6884.0
CHD9 -6868.0
RPSA -6847.0
RAI1 -6759.0
CBX8 -6705.0
SKP1 -6672.0
RPL36 -6664.0
CAPZA2 -6624.0
NR3C1 -6622.0
MT2A -6561.0
RPS28 -6540.0
CCNA2 -6534.0
TUBA1C -6503.0
NUP160 -6475.0
SEC13 -6469.0
SIRT1 -6458.0
PLA2G4B -6437.0
H2BC1 -6434.0
CDKN1B -6381.0
H1-3 -6378.0
NR3C2 -6368.0
MAP3K5 -6350.0
NPLOC4 -6329.0
ANAPC5 -6314.0
ALB -6293.0
AKT2 -6287.0
LY96 -6285.0
RAE1 -6238.0
DIS3 -6209.0
DYNC1LI2 -6196.0
CAPZB -6166.0
LMNB1 -6160.0
SZT2 -6135.0
CEBPB -6129.0
UBE2E1 -6123.0
COX20 -6100.0
PSMC3 -6093.0
NCOR2 -6078.0
RPL21 -6077.0
CUL3 -6004.0
CITED2 -5996.0
RPL30 -5982.0
TUBAL3 -5968.0
ACD -5957.5
SKP2 -5945.0
MAP1LC3B -5933.0
HIKESHI -5912.0
PSMD13 -5903.0
IFNB1 -5863.0
GPX1 -5851.0
CDKN2A -5841.0
NUDT2 -5836.0
COX19 -5834.0
UBE2S -5833.0
HSPA8 -5803.0
YIF1A -5770.0
RPL26 -5760.0
NUP155 -5740.0
CRTC3 -5715.0
SLC38A9 -5681.0
CUL7 -5671.0
NPRL2 -5640.0
SOD2 -5618.0
SQSTM1 -5563.0
H3-3B -5536.0
RPL10A -5530.0
NUP88 -5526.0
CCNE1 -5513.0
HM13 -5491.0
H2BC8 -5414.0
H3C4 -5404.0
H3-3A -5377.0
HSPA1B -5362.0
LAMTOR1 -5340.0
E2F3 -5327.0
RPS15 -5286.0
FNIP2 -5260.0
HYOU1 -5189.0
HMOX2 -5188.0
RRAGC -5175.0
GFPT1 -5169.0
TRIM21 -5158.0
TNIK -5126.0
PSMA2 -5113.0
CBX6 -5107.0
FBXL17 -5092.0
PSMD8 -5084.0
TCIRG1 -5047.0
DYNC1H1 -5010.0
TFDP1 -5000.0
RPL19 -4989.0
DCTN6 -4973.0
RPLP0 -4937.0
PRDX6 -4911.0
RNF2 -4904.0
FKBP14 -4890.0
EXOSC2 -4886.0
NDUFA4 -4859.0
GOSR2 -4852.0
PRDX2 -4823.0
RPS12 -4819.0
RPS16 -4777.0
MT1X -4745.0
DYNC1I2 -4740.0
H2AC4 -4647.0
GCLM -4640.0
NFE2L2 -4638.0
HSPA4L -4632.0
PSMA1 -4584.0
BAG2 -4560.0
H3C8 -4535.0
COX6B1 -4497.0
HSPA14 -4486.0
RPL36AL -4483.5
MED1 -4465.0
RPS10 -4458.0
RPL7 -4455.0
NUP58 -4439.0
TBL1XR1 -4414.0
EXOSC5 -4400.0
CLOCK -4359.0
RPS6 -4356.0
ATP6V0D1 -4275.0
RPS27L -4266.0
GPX7 -4199.0
KLHDC3 -4182.0
H1-4 -4179.0
CYCS -4168.0
CREB3L2 -4157.0
MAPKAPK3 -4102.0
H2BC11 -4063.0
RPL18 -4060.0
CDC27 -4048.0
RBX1 -4039.0
PSMB3 -4011.0
EGLN3 -4001.0
EXOSC9 -3979.0
EXOSC6 -3940.0
NUP188 -3926.0
MAPK7 -3897.0
RPS21 -3875.0
COX5B -3858.0
ERN1 -3855.0
RHEB -3824.0
PSME4 -3807.0
GPX5 -3803.0
RPS8 -3769.0
ATP6V0E1 -3766.0
RPS18 -3746.0
HMGA2 -3733.0
CBX4 -3688.0
NFYB -3674.0
E2F1 -3673.0
RPL17 -3669.0
ANAPC2 -3595.0
H4C13 -3564.0
ANAPC10 -3558.0
NCOA1 -3556.0
RORA -3515.0
PALB2 -3500.0
ERO1A -3437.0
PPARGC1A -3425.0
XPO1 -3414.0
DCTN1 -3378.0
ATP6V1F -3369.0
DNAJB11 -3355.0
PRDX1 -3352.0
NCF4 -3338.0
SLC7A11 -3321.0
HSF1 -3314.0
ATP6V1H -3298.0
DNAJC7 -3273.0
EIF2AK4 -3272.0
DNAJB1 -3227.0
PRDX5 -3225.0
DEPDC5 -3205.0
ASF1A -3195.0
EXTL2 -3193.0
ATP6V1E2 -3177.0
ETS1 -3176.0
POT1 -3175.0
GSR -3160.0
MAPK1 -3156.0
TLR4 -3136.0
MT1F -3135.0
CREBRF -3125.0
ERF -3124.0
PSMB1 -3117.0
MAPK3 -3089.0
RPL27 -3082.0
AGO3 -3073.0
UBN1 -3061.0
MYDGF -3059.0
CCAR2 -3040.0
PHC2 -3014.0
EXTL3 -2995.0
GSTP1 -2991.0
MBTPS1 -2990.0
CUL1 -2987.0
JUN -2945.0
EED -2898.0
EGLN1 -2892.0
NRIP1 -2871.0
HIRA -2827.0
NOTCH1 -2808.0
HSPA1L -2798.0
EXOSC3 -2772.0
PSMA7 -2759.0
HDAC3 -2723.0
MDM4 -2718.0
SESN2 -2675.0
ATM -2668.0
UFD1 -2657.0
GSK3B -2656.0
PDIA6 -2652.0
RPL14 -2574.0
DEDD2 -2546.0
HSPA2 -2545.0
RPLP2 -2532.0
APOA1 -2522.0
PSMF1 -2512.0
HSP90AA1 -2504.0
EZH2 -2496.0
H4C2 -2432.0
GPX3 -2420.0
NCOA6 -2407.0
PDIA5 -2401.0
CARM1 -2380.0
MAP4K4 -2334.0
RPS19BP1 -2256.0
AKT1 -2241.0
EHMT2 -2233.0
CREB1 -2161.0
CAT -2137.0
ELOC -2118.0
DNAJB9 -2108.0
ATOX1 -2106.0
TERF2 -2059.0
BLVRB -2052.0
CASTOR1 -2051.0
FLCN -2036.0
COX7C -2020.0
NPRL3 -2016.0
RPA1 -2002.0
HSP90AB1 -1956.0
GCN1 -1942.0
NFYC -1931.0
H2AZ2 -1872.0
ANAPC11 -1849.0
PSMC1 -1839.0
PSMA6 -1800.0
TGS1 -1797.0
DCP2 -1775.0
DCTN3 -1770.0
EP400 -1729.0
TLN1 -1694.0
CDKN1A -1607.0
CREBBP -1603.0
HMGA1 -1568.0
ACADVL -1543.0
BAG5 -1531.0
HBA2 -1527.0
AAAS -1523.0
RPS20 -1511.0
ASNS -1484.0
CUL2 -1439.0
NQO1 -1435.0
PGD -1421.0
SRPRA -1413.0
RPS9 -1361.0
VHL -1347.0
RPL5 -1340.0
MAPK10 -1331.0
TPR -1291.0
MAPKAPK2 -1227.0
BMT2 -1224.0
ATF6 -1191.0
EGLN2 -1177.0
RANBP2 -1170.0
HDGF -1147.0
TUBB4B -1137.0
COX16 -1117.0
H2AC8 -1109.0
DNAJB6 -1107.0
TERF2IP -1096.0
SRPRB -1092.0
EXOSC8 -994.0
H2AJ -963.0
CCNA1 -948.0
RPL8 -941.0
NUP153 -930.0
E2F2 -920.0
FOS -894.0
NUP93 -887.0
AKT1S1 -877.0
ADD1 -871.0
CBX2 -849.0
PSMD1 -818.0
YWHAE -811.0
PRKCD -789.0
RPS11 -773.0
MYC -745.0
RING1 -740.0
ATP6V1B2 -738.0
BTRC -717.0
HIF1AN -702.0
SURF1 -695.0
UBB -665.0
SRXN1 -660.0
PSMA4 -648.0
COX6C -638.0
NDC1 -624.0
DCSTAMP -623.0
WDR24 -591.0
PPP1R15A -562.0
RPS14 -538.0
NFKB1 -487.0
MAP2K4 -452.0
TNRC6A -436.0
MAPK9 -429.0
SYVN1 -374.0
KEAP1 -351.0
SCMH1 -327.0
PGR -310.0
ANAPC4 -298.0
BMAL1 -271.0
DYNC1I1 -230.0
ATR -207.0
DNAJC2 -163.0
MEF2C -155.0
RPS27A -126.0
ME1 -122.0
MRPL18 -117.0
H4C12 -107.0
ID1 -106.0
MT3 -65.0
MLST8 -52.0
SESN1 -50.0
ATF4 -2.0
ATP6V1G1 6.0
CAMK2D 13.0
STIP1 129.0
SERPINH1 135.0
MDM2 136.0
RPLP1 175.0
CTDSP2 186.0
RPS7 193.0
NFYA 250.0
TUBB2A 305.0
H4C1 323.0
COX6A1 341.0
RPL12 342.0
WDR59 355.0
AGO1 376.0
TXNRD1 473.0
CHAC1 476.0
CYBA 541.0
IDH1 598.0
MINK1 600.0
H4C8 685.0
COX14 690.0
RXRA 721.0
TRIB3 741.0
SSR1 806.0
TXN2 807.0
MUL1 831.0
H2BC17 842.0
H2AX 876.0
RPS19 887.0
PSMD11 1023.0
CEBPG 1027.0
UBE2D2 1066.0
TINF2 1072.0
EDEM1 1131.0
GCLC 1133.0
TNFRSF21 1154.0
NUP43 1180.0
RPA3 1184.0
MTOR 1189.0
AKT3 1209.0
HIF1A 1245.0
RPL15 1283.0
PSMB4 1285.0
RPL28 1298.0
PSMA5 1304.0
ATP6V0B 1399.0
CAMK2G 1409.0
P4HB 1473.0
RPL22 1475.0
CDK4 1550.0
CCS 1557.0
PSMC4 1596.0
BAG3 1646.0
PTGES3 1666.0
PHC3 1727.0
H3C11 1739.0
PPARA 1763.0
NLRP3 1824.0
CABIN1 2002.0
PSME2 2084.0
RPL41 2146.0
RPL37 2151.0
HBB 2165.0
RPS27 2171.0
EXOSC1 2226.0
FABP1 2245.0
GSTA1 2265.0
HSPB1 2306.0
RPA2 2309.0
RPS15A 2354.0
NUP85 2430.0
HSPH1 2440.0
H3C10 2461.0
ARFGAP1 2492.0
H4C5 2528.0
RPS29 2538.0
RPS3 2573.0
RPL34 2588.0
RRAGD 2628.0
UBE2D1 2677.0
DDIT3 2702.0
TUBA3D 2717.0
AJUBA 2746.0
MAP2K3 2764.0
RPL27A 2771.0
HIGD1A 2788.0
NUP205 2803.0
MAFK 2804.0
PSMD12 2806.0
SNCB 2826.0
ANAPC1 2923.0
ATP6V1G3 2995.0
EIF2AK1 3124.0
NUP133 3158.0
EHMT1 3168.0
TNRC6C 3185.0
RRAGA 3202.0
PPP2R5B 3218.0
NUP54 3235.0
NUP210 3259.0
GSTA3 3272.0
NR1D1 3280.0
ATF2 3306.0
DCTN5 3352.0
TUBB6 3395.0
RPS3A 3411.0
HSPA9 3415.0
RPTOR 3471.0
MAPK8 3528.0
TACO1 3550.0
RPS13 3598.0
SH3BP4 3627.0
BLVRA 3630.0
CSNK2A1 3638.0
PSMD14 3679.0
RPS6KA2 3715.0
ATP6V1G2 3716.0
H3C2 3733.0
MAP2K7 3747.0
RPS2 3762.0
NCOR1 3766.0
LRPPRC 3771.0
VEGFA 3867.0
DNAJA1 3927.0
H1-0 3967.0
HELZ2 3984.0
NOX4 4002.0
CDKN2B 4021.0
RPL6 4045.0
RPS25 4057.0
ATP6V0D2 4064.0
H4C4 4097.0
ST13 4122.0
NCF2 4142.0
STAP2 4195.0
RPL26L1 4216.0
RPS24 4241.0
HSPA5 4266.0
MT1E 4338.0
PSMB6 4375.0
CRTC1 4388.0
H2AZ1 4397.0
TALDO1 4543.0
MAPK11 4578.0
RPL22L1 4607.0
MT1A 4677.0
RPL18A 4718.0
NUP35 4792.0
RPL38 4807.0
IGFBP7 4831.0
H4C16 4865.0
LAMTOR5 5050.0
TUBB1 5090.0
APOB 5113.0
RPL9 5114.0
NOX5 5193.0
RAD50 5232.0
CA9 5291.0
TATDN2 5316.0
MEF2D 5351.0
ATF5 5372.0
H4C6 5430.0
HMOX1 5467.0
IMPACT 5470.0
NUP62 5471.0
CREB3L3 5498.0
EPAS1 5562.0
SEM1 5631.0
TP53 5757.0
EPO 5792.0
TXNRD2 5816.0
GPX8 5949.0
DYNLL2 5999.0
TUBA4B 6042.0
KDELR3 6065.0
PHC1 6131.0
ATF3 6142.0
ANAPC15 6148.0
RPL39L 6167.0
PSMD4 6169.0
RPL3 6195.0
COX5A 6246.0
NPAS2 6253.0
UBA52 6282.0
TUBB4A 6369.0
RPL13A 6422.5
TUBA4A 6664.0
PSMD5 6795.0
GRB10 6806.0
HSPA12A 6855.0
TUBB3 6928.0
MT1H 6946.0
RELA 6961.0
HIF3A 6965.0
CAMK2B 7010.0
H3-4 7087.0
GPX6 7287.0
WFS1 7430.0
COX8A 7527.0
WTIP 7643.0
MT1B 7693.0
HSPA12B 7739.0
ATP6V1C2 7776.0
CLEC1B 7803.0
CRYBA4 7839.0
LMNA 7850.0
TUBB2B 7929.0
MT4 8135.0
TUBA8 8140.0
DNAJA4 8232.0
VENTX 8299.0
ZBTB17 8313.0
POM121C 8315.0
CCL2 8464.0
RPL29 8479.0
GML 8647.0
IGFBP1 8706.0
UBE2C 8787.0
MT1G 8893.0
SMARCD3 8913.0
PTK6 8932.0
DDX11 8948.0
GPX2 8949.0
H1-1 8990.0
EXTL1 9190.0
AQP8 9479.0
PSMB11 9506.0
TUBB8 9559.0
HSPA6 9642.0
CDKN2D 9657.0
CRYAB 9708.0
SOD3 9709.0
HBA1 9795.0
CREB3L1 9815.0
CAMK2A 9899.0
MT1M 9907.0
HSBP1 9987.0
PREB 9994.0
IL1A 10020.0
ATP6V1B1 10102.0
RPL3L 10336.0
HSPB2 10371.0
HSPB8 10405.0


REACTOME_DNA_REPAIR

REACTOME_DNA_REPAIR
1168
set REACTOME_DNA_REPAIR
setSize 321
pANOVA 2.44e-16
s.dist -0.266
p.adjustANOVA 5.72e-14



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
RAD23A -10762.0
H2AC14 -10727.0
ISG15 -10624.0
ASCC3 -10398.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
XRCC2 -10262.0
H2BC12 -10245.0
UBA7 -10234.0
COPS7B -10227.0
H2AC20 -10208.0
BRCA1 -10206.0
H2BC15 -10189.0
MSH6 -10043.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
RAD23A -10762.0
H2AC14 -10727.0
ISG15 -10624.0
ASCC3 -10398.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
XRCC2 -10262.0
H2BC12 -10245.0
UBA7 -10234.0
COPS7B -10227.0
H2AC20 -10208.0
BRCA1 -10206.0
H2BC15 -10189.0
MSH6 -10043.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
LIG1 -9941.0
PPP5C -9699.0
WDR48 -9688.0
EP300 -9652.0
PIAS1 -9633.0
FANCL -9578.0
YY1 -9573.0
FAAP24 -9562.0
MCRS1 -9509.0
HUS1 -9493.0
SLX4 -9415.0
ERCC3 -9371.0
UNG -9360.0
H2BC26 -9346.0
POLL -9330.0
H2BC4 -9285.0
COPS3 -9283.0
PRPF19 -9140.0
RNF8 -9099.0
PPP4R2 -9086.0
H2BC9 -9020.5
UBE2T -8923.0
TDP1 -8873.0
POLI -8762.0
EXO1 -8718.0
PAXIP1 -8605.0
AQR -8601.0
XRCC3 -8583.0
H2BC3 -8572.0
H4C3 -8451.0
GTF2H3 -8449.0
H2AC6 -8428.0
SIRT6 -8427.0
PIAS3 -8391.0
PCNA -8301.0
DCLRE1A -8283.0
UBC -8277.0
RMI2 -8269.0
UBE2V2 -8249.0
POLD3 -8233.0
COPS5 -8199.0
H2BC10 -8174.0
TERF1 -8166.0
ACTR5 -8146.0
KAT5 -8114.0
FTO -8091.0
ERCC5 -8028.0
RAD9A -8023.0
POLK -7966.0
EYA1 -7921.0
CUL4A -7832.0
CDK2 -7826.0
ERCC2 -7814.0
PNKP -7747.0
MRE11 -7695.0
GTF2H1 -7675.0
MNAT1 -7673.0
INO80 -7662.0
H4C11 -7658.0
TIPIN -7651.0
RFC3 -7597.0
H2BC13 -7580.0
CCNH -7537.0
FAN1 -7531.0
RAD51 -7507.0
FANCG -7473.0
FEN1 -7452.0
COPS4 -7428.0
COPS7A -7396.0
ERCC4 -7365.0
HERC2 -7359.0
INO80D -7350.0
NBN -7344.0
POLE4 -7340.0
H2BC5 -7339.0
ALKBH3 -7289.0
ELL -7225.0
SUMO1 -7196.0
BLM -7176.0
RNF168 -7116.0
RFC1 -7068.0
MBD4 -6995.0
VCP -6884.0
POLR2H -6881.0
ASCC2 -6813.0
BABAM1 -6706.0
CCNA2 -6534.0
H2BC1 -6434.0
POLD2 -6366.0
NPLOC4 -6329.0
FANCM -6295.0
PIAS4 -6095.0
POLR2L -5972.0
ACD -5957.5
ABRAXAS1 -5893.0
HMGN1 -5848.0
MPG -5703.0
DDB2 -5674.0
DCLRE1C -5670.0
POLR2K -5634.0
ACTR8 -5606.0
RFC4 -5573.0
ABL1 -5559.0
RAD52 -5549.0
H2BC8 -5414.0
CDK7 -5280.0
GEN1 -5275.0
FANCI -5274.0
INO80C -5235.0
ATRIP -5204.0
RCHY1 -5086.0
BAP1 -5052.0
TOPBP1 -5020.0
RAD18 -4976.0
NSD2 -4972.0
PARP2 -4867.0
MSH2 -4838.0
BRCA2 -4816.0
TDG -4767.0
USP45 -4719.0
H2AC4 -4647.0
FANCC -4553.0
PMS2 -4508.0
POLD4 -4479.0
ASCC1 -4441.0
PARP1 -4415.0
RMI1 -4357.0
XPA -4297.0
RBBP8 -4231.0
WRN -4227.0
TRIM25 -4186.0
POLM -4078.0
H2BC11 -4063.0
POLQ -4054.0
RBX1 -4039.0
RIF1 -4017.0
DTL -4012.0
BAZ1B -3951.0
POLR2G -3937.0
NEIL2 -3782.0
MLH1 -3770.0
POLR2B -3768.0
XPC -3728.0
TP53BP1 -3633.0
NFRKB -3616.0
POLE -3565.0
H4C13 -3564.0
SUMO2 -3536.0
POLB -3527.0
PALB2 -3500.0
SPRTN -3252.0
RAD23B -3238.0
POT1 -3175.0
COPS2 -3151.0
TOP3A -3093.0
FANCA -3085.0
USP1 -2989.0
RNF111 -2896.0
ZNF830 -2810.0
MUTYH -2729.0
ATM -2668.0
UFD1 -2657.0
DCLRE1B -2640.0
FAAP100 -2585.0
NEIL3 -2572.0
CLSPN -2497.0
H4C2 -2432.0
UBE2B -2392.0
XRCC6 -2338.0
TERF2 -2059.0
RPA1 -2002.0
FANCD2 -1968.0
ERCC1 -1963.0
INO80E -1938.0
H2AZ2 -1872.0
RFC5 -1846.0
RHNO1 -1742.0
POLR2I -1736.0
RNF4 -1554.0
EME2 -1551.0
RUVBL1 -1380.0
SUMO3 -1301.0
POLR2A -1290.0
ERCC6 -1248.0
ERCC8 -1178.0
DNA2 -1113.0
H2AC8 -1109.0
TERF2IP -1096.0
LIG3 -984.0
H2AJ -963.0
CCNA1 -948.0
GTF2H5 -806.0
UBB -665.0
PRKDC -539.0
REV3L -518.0
XAB2 -464.0
SMARCA5 -420.0
RAD17 -303.0
ATR -207.0
RTEL1 -180.0
XRCC5 -134.0
RPS27A -126.0
H4C12 -107.0
RAD1 -102.0
ALKBH5 -70.0
BARD1 -51.0
POLH -44.0
MUS81 -30.0
POLE3 87.0
APEX1 100.0
GTF2H4 183.0
POLR2C 198.0
TFPT 245.0
USP7 268.0
MSH3 294.0
RAD9B 312.0
RAD51B 313.0
H4C1 323.0
CHD1L 343.0
FANCE 350.0
POLE2 373.0
POLR2E 503.0
UBE2I 578.0
RAD51AP1 616.0
H4C8 685.0
LIG4 837.0
H2BC17 842.0
H2AX 876.0
CHEK2 921.0
TINF2 1072.0
ACTL6A 1091.0
REV1 1105.0
EYA4 1172.0
RPA3 1184.0
NTHL1 1196.0
UVSSA 1205.0
MGMT 1215.0
POLD1 1233.0
BRIP1 1255.0
UBE2N 1276.0
BABAM2 1393.0
CENPS 1636.0
TDP2 1702.0
SPIDR 1796.0
EYA3 1923.0
RFC2 1966.0
RAD51D 2111.0
KDM4A 2264.0
RPA2 2309.0
CHEK1 2332.0
POLR2D 2370.0
INO80B 2396.0
FAAP20 2432.0
ALKBH2 2490.0
H4C5 2528.0
COPS8 2631.0
KPNA2 2633.0
MDC1 2996.0
SMUG1 3080.0
ACTB 3141.0
COPS6 3142.0
POLR2F 3184.0
XRCC4 3215.0
PPP4C 3274.0
KDM4B 3377.0
MAPK8 3528.0
DDB1 3608.0
POLR2J 3674.0
UIMC1 3738.0
H4C4 4097.0
RAD51C 4234.0
H2AZ1 4397.0
NEIL1 4415.0
TIMELESS 4630.0
XRCC1 4660.0
FANCF 4848.0
H4C16 4865.0
RAD50 5232.0
PPIE 5253.0
UBXN1 5266.0
H4C6 5430.0
SEM1 5631.0
APBB1 5754.0
TP53 5757.0
UBE2L6 5836.0
USP10 5891.0
EYA2 5932.0
TCEA1 6002.0
GPS1 6067.0
POLN 6147.0
UBA52 6282.0
PARG 6341.0
MAD2L2 6373.0
ISY1 6542.0
NHEJ1 6790.0
PCLAF 6898.0
EME1 7024.0
H3-4 7087.0
ADPRS 7161.0
OGG1 8175.0
USP43 9176.0


REACTOME_INFECTIOUS_DISEASE

REACTOME_INFECTIOUS_DISEASE
974
set REACTOME_INFECTIOUS_DISEASE
setSize 910
pANOVA 2.01e-15
s.dist -0.155
p.adjustANOVA 4.13e-13



Top enriched genes

Top 20 genes
GeneID Gene Rank
CTSG -11093
H2BC14 -11029
RPL10L -11011
BRD4 -11010
CALR -10983
IL10 -10942
H3C6 -10917
FXYD1 -10889
H3C12 -10877
H3C3 -10808
DNAJC3 -10775
CYSLTR2 -10747
H2AC14 -10727
PIK3R4 -10693
H2AC12 -10676
FCGR3A -10654
PSMB7 -10651
RPL35A -10631
ISG15 -10624
PSMC6 -10621

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CTSG -11093.0
H2BC14 -11029.0
RPL10L -11011.0
BRD4 -11010.0
CALR -10983.0
IL10 -10942.0
H3C6 -10917.0
FXYD1 -10889.0
H3C12 -10877.0
H3C3 -10808.0
DNAJC3 -10775.0
CYSLTR2 -10747.0
H2AC14 -10727.0
PIK3R4 -10693.0
H2AC12 -10676.0
FCGR3A -10654.0
PSMB7 -10651.0
RPL35A -10631.0
ISG15 -10624.0
PSMC6 -10621.0
GNAS -10554.0
TXN -10530.0
RPL37A -10509.0
IL1B -10483.0
STING1 -10467.0
GEMIN2 -10426.0
IFNGR2 -10420.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
CRBN -10278.0
GTF2A2 -10268.0
H2BC12 -10245.0
PSMD2 -10209.0
H2AC20 -10208.0
H2BC15 -10189.0
CNBP -10137.0
PSMC2 -10087.0
RB1 -10080.0
CLTA -10065.0
RPN2 -10062.0
HLA-A -10047.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
NOD1 -10009.0
LIG1 -9941.0
PARP9 -9899.0
ELOB -9858.0
BECN1 -9853.0
PSMA3 -9831.0
IFNA5 -9817.0
JAK3 -9814.0
SUPT16H -9810.0
B2M -9792.0
ST3GAL4 -9789.0
TUBA1A -9776.0
TUBA3E -9762.0
SP1 -9694.0
TUSC3 -9674.0
PIK3C3 -9658.0
EP300 -9652.0
MAPK14 -9643.0
ANO3 -9640.0
RPL11 -9622.0
PSMB8 -9616.0
MAP2K6 -9611.0
CDC42 -9607.0
RIPK3 -9569.0
RPS5 -9536.0
PARP6 -9535.0
TAB2 -9532.0
RNGTT -9516.0
H2AC15 -9502.0
SRPK1 -9497.0
IL6 -9492.0
ROCK2 -9424.0
PSME1 -9420.0
ERCC3 -9371.0
NELFB -9365.0
H2BC26 -9346.0
PSMC5 -9310.0
NUP37 -9289.0
H2BC4 -9285.0
GALNT1 -9257.0
YWHAZ -9228.0
GPS2 -9206.0
NCK1 -9181.0
VAV1 -9148.0
GEMIN6 -9104.0
HSPA1A -9068.0
RPS23 -9056.0
BST2 -9045.0
MOGS -9044.0
NMT2 -9041.0
ATG14 -9040.0
PSMA8 -9037.0
ARID4A -9035.0
H2BC9 -9020.5
H3C7 -9020.5
CHMP4B -9016.0
PPIH -9013.0
KPNB1 -8945.0
NCKAP1L -8929.0
DYNLL1 -8928.0
TUBA3C -8877.0
RPL24 -8875.0
NUP50 -8870.0
H2AC13 -8863.0
KPNA1 -8859.0
VPS4A -8856.0
TBK1 -8855.0
ADORA2B -8845.0
ABI2 -8825.0
TOMM70 -8822.0
RPL32 -8790.0
SH3GL1 -8724.0
POM121 -8700.0
FGR -8696.0
HNRNPA1 -8664.0
PSME3 -8645.0
RPL4 -8640.0
SNAP25 -8631.0
SUZ12 -8594.0
IMPDH1 -8578.0
H2BC3 -8572.0
CSNK1A1 -8567.0
GNG10 -8561.0
RPL23A -8537.0
CHMP4C -8524.0
GNG3 -8510.0
PSMD3 -8488.0
H4C3 -8451.0
GTF2H3 -8449.0
H2AC6 -8428.0
SAP30 -8418.0
CHMP5 -8412.0
NUP42 -8381.0
NMI -8357.0
UBC -8277.0
PPIA -8272.0
TAF3 -8256.0
ISCU -8240.0
RUNX1 -8234.0
NCBP1 -8209.0
FNTA -8203.0
FAU -8194.0
H2BC10 -8174.0
SEH1L -8137.0
NUP98 -8136.0
PRMT1 -8128.0
CHMP1A -8115.0
SMAD3 -8098.0
MGAT4A -8097.0
ANO4 -8093.0
SAP18 -8083.0
RPL23 -8055.0
PSMD6 -8047.0
RPL13 -8037.0
NUP107 -7996.0
CTNND1 -7980.0
IFIH1 -7904.0
DDX20 -7891.0
TAF10 -7853.0
ERCC2 -7814.0
ITPR1 -7781.0
PPIB -7775.0
DVL1 -7768.0
NPM1 -7766.0
AP2S1 -7718.0
GSDMD -7715.0
ARID4B -7690.0
ZDHHC20 -7685.0
GTF2H1 -7675.0
MNAT1 -7673.0
EEF1A1 -7671.0
SNRPB -7665.0
GTF2B -7664.0
H4C11 -7658.0
NCKAP1 -7622.0
H2BC13 -7580.0
PSMB10 -7549.0
CCNH -7537.0
H3C1 -7492.0
GSK3A -7471.0
PSMD7 -7470.0
FEN1 -7452.0
IKBKB -7451.0
SMAD4 -7434.0
CCNT2 -7431.0
ITCH -7429.0
STAM -7421.0
CTDP1 -7416.0
RPL7A -7402.0
H2AC21 -7400.0
IRF3 -7388.0
ROCK1 -7387.0
PSMB5 -7376.0
CHMP6 -7353.0
H2BC5 -7339.0
STT3A -7335.0
RPL35 -7326.0
YWHAG -7293.0
RPL31 -7280.0
RBBP4 -7271.0
KPNA4 -7244.0
LYN -7229.0
MGAT4C -7226.0
ELL -7225.0
RPS26 -7213.0
SUMO1 -7196.0
TUBA1B -7184.0
ITPR2 -7172.0
ST3GAL2 -7167.0
KDM1A -7160.0
HNRNPK -7107.0
MTA2 -7100.0
RIPK1 -7072.0
TXNIP -7065.0
DYNC1LI1 -7041.0
ELMO1 -7033.0
MAP3K7 -7012.0
GATAD2B -7010.0
SRPK2 -7005.0
PSMB2 -7000.0
PSMB9 -6985.0
PSMD9 -6972.0
FKBP4 -6928.0
IL6R -6901.0
NUP214 -6894.0
VCP -6884.0
POLR2H -6881.0
ST3GAL1 -6873.0
RPSA -6847.0
HLA-C -6808.0
IRF7 -6785.0
WASF2 -6781.0
IFNA1 -6770.0
TAF15 -6684.0
TAF2 -6681.0
SKP1 -6672.0
RPL36 -6664.0
NR3C1 -6622.0
RPS28 -6540.0
TUBA1C -6503.0
EPS15 -6478.0
NUP160 -6475.0
SEC13 -6469.0
H2BC1 -6434.0
NMT1 -6377.0
NOXA1 -6365.0
VPS37D -6348.0
H2AC25 -6343.0
YES1 -6326.0
ACTR2 -6324.0
ENO1 -6303.0
AP2A1 -6298.0
AKT2 -6287.0
VPS33A -6274.0
RAE1 -6238.0
HBEGF -6218.0
GTF2E1 -6214.0
DYNC1LI2 -6196.0
GEMIN7 -6183.0
PHF21A -6152.0
STAT2 -6148.0
CBX1 -6145.0
PSMC3 -6093.0
NCOR2 -6078.0
RPL21 -6077.0
VPS33B -6066.0
TAF1L -6049.0
TYK2 -6026.0
TRIM4 -6020.0
CUL3 -6004.0
ELMO2 -5986.0
RPL30 -5982.0
PSIP1 -5973.0
POLR2L -5972.0
TUBAL3 -5968.0
RAC1 -5965.0
GRSF1 -5953.0
MAP1LC3B -5933.0
HDAC1 -5913.0
PSMD13 -5903.0
CHMP7 -5878.0
IFNB1 -5863.0
FUT8 -5825.0
SUGT1 -5822.0
RPL26 -5760.0
NUP155 -5740.0
VPS25 -5721.0
GRB2 -5691.0
POLR2K -5634.0
ADCY2 -5626.0
GPC6 -5590.0
ABL1 -5559.0
ARF1 -5546.0
RPL10A -5530.0
NUP88 -5526.0
ELOA -5519.0
RANBP1 -5514.0
MBD3 -5490.0
PML -5486.0
WNT5A -5461.0
IL17F -5424.0
H2BC8 -5414.0
CHUK -5407.0
H3C4 -5404.0
WIPF2 -5398.0
RANGAP1 -5347.0
BRMS1 -5339.0
RPS15 -5286.0
CDK7 -5280.0
CASP1 -5264.0
ANTXR2 -5257.0
APP -5218.0
TSG101 -5215.0
MAN2A1 -5197.0
RIGI -5177.0
NELFE -5152.0
TUBB -5144.0
PSMA2 -5113.0
PSMD8 -5084.0
BANF1 -5058.0
SAR1B -5057.0
SFPQ -5044.0
DYNC1H1 -5010.0
RPL19 -4989.0
FYN -4977.0
RPLP0 -4937.0
SEC24D -4905.0
CRK -4882.0
SOS1 -4879.0
STX1A -4854.0
RPS12 -4819.0
VPS37C -4783.0
RPS16 -4777.0
DYNC1I2 -4740.0
EIF2AK2 -4733.0
IFNGR1 -4683.0
PDCD6IP -4663.0
H2AC4 -4647.0
NFE2L2 -4638.0
PSMA1 -4584.0
ITGB1 -4570.0
PDPK1 -4559.0
H3C8 -4535.0
VPS16 -4489.0
MGAT2 -4483.5
RPL36AL -4483.5
EDEM2 -4468.0
RPS10 -4458.0
RPL7 -4455.0
NUP58 -4439.0
RAN -4434.0
GNAI3 -4432.0
SUDS3 -4430.0
PARP1 -4415.0
TBL1XR1 -4414.0
NELFCD -4386.0
HDAC2 -4377.0
RPS6 -4356.0
TJP1 -4314.0
MGAT1 -4280.0
RPS27L -4266.0
MYO9B -4232.0
UVRAG -4187.0
TRIM25 -4186.0
ARPC1A -4158.0
SEC24A -4150.0
AP2A2 -4109.0
SNRPD3 -4100.0
IL18 -4081.0
H2BC11 -4063.0
RPL18 -4060.0
RBX1 -4039.0
PSMB3 -4011.0
PAK2 -3995.0
TRAF6 -3985.0
H2AC1 -3983.0
ZDHHC2 -3961.0
POLR2G -3937.0
NUP188 -3926.0
PALS1 -3899.0
MAVS -3892.0
ANO6 -3889.0
AP1G1 -3883.0
RPS21 -3875.0
VAV3 -3870.0
PCBP2 -3820.0
PSME4 -3807.0
ACTR3 -3798.0
RPS8 -3769.0
POLR2B -3768.0
RPS18 -3746.0
ZCRB1 -3735.0
ARPC3 -3699.0
AP1B1 -3679.0
RPL17 -3669.0
P2RX4 -3658.0
GNB5 -3644.0
TAF5 -3594.0
AP1M1 -3575.0
H4C13 -3564.0
ZDHHC3 -3456.0
TAF11 -3452.0
AP2M1 -3441.0
CHD3 -3438.0
XPO1 -3414.0
ARPC4 -3392.0
PARP14 -3365.0
GOLGA7 -3358.0
RCOR1 -3356.0
FNTB -3310.0
ATP6V1H -3298.0
HMG20B -3275.0
VPS4B -3269.0
STAT1 -3268.0
FZD7 -3253.0
ENTPD5 -3235.0
H2AC17 -3211.0
CBL -3209.0
RCC1 -3204.0
MAPK1 -3156.0
SNF8 -3150.0
VAMP2 -3140.0
PSMB1 -3117.0
NOD2 -3115.0
CLTC -3107.0
MAPK3 -3089.0
RPL27 -3082.0
ANO8 -3081.0
SV2C -3077.0
VAMP1 -3069.0
VPS36 -3033.0
PATJ -3032.0
AHCYL1 -3022.0
TAF6 -3011.0
NLRP12 -2968.0
JUN -2945.0
TLR2 -2930.0
EED -2898.0
GPC5 -2867.0
PRKAR1A -2835.0
SNRPD2 -2767.0
GTF2F2 -2764.0
PSMA7 -2759.0
TUFM -2756.0
TAF4 -2733.0
HDAC3 -2723.0
GANAB -2722.0
GJA1 -2698.0
GSK3B -2656.0
RHBDF2 -2625.0
PSTPIP1 -2618.0
SEC24C -2586.0
IFNAR2 -2581.0
RPL14 -2574.0
MYH2 -2557.0
RPLP2 -2532.0
PSMF1 -2512.0
HSP90AA1 -2504.0
EZH2 -2496.0
VPS37B -2493.0
PABPN1 -2472.0
WASL -2457.0
SIKE1 -2451.0
NCBP2 -2442.0
H4C2 -2432.0
JAK2 -2403.0
P2RX7 -2355.0
ATP1B3 -2350.0
GEMIN4 -2339.0
XRCC6 -2338.0
GGT1 -2329.0
CHMP4A -2308.0
WASF1 -2304.0
GNAT3 -2264.0
AKT1 -2241.0
GPC1 -2230.0
PRKCSH -2214.0
CREB1 -2161.0
ELOC -2118.0
G3BP1 -1964.0
HSP90AB1 -1956.0
PSMC1 -1839.0
PSMA6 -1800.0
TRIM27 -1778.0
POLR2I -1736.0
CXCR4 -1674.0
ACTG1 -1669.0
MVB12A -1668.0
CREBBP -1603.0
PPIG -1581.0
HMGA1 -1568.0
STAM2 -1567.0
AAAS -1523.0
RPS20 -1511.0
CHD4 -1434.0
GTF2A1 -1415.0
SYT1 -1407.0
ITPR3 -1366.0
SNRPE -1363.0
RPS9 -1361.0
VHL -1347.0
VPS41 -1344.0
RPL5 -1340.0
TPR -1291.0
POLR2A -1290.0
H2AC11 -1249.0
DPEP3 -1185.0
RANBP2 -1170.0
TUBB4B -1137.0
GNAZ -1136.0
H2AC8 -1109.0
TAF13 -1085.0
IPO5 -1067.0
MGAT4B -1034.0
HLA-G -1030.0
SUPT5H -997.0
RAB7A -993.0
GNB1 -959.0
RPL8 -941.0
NUP153 -930.0
NUP93 -887.0
ENTPD1 -883.0
FURIN -867.0
VPS28 -844.0
PSMD1 -818.0
YWHAE -811.0
GTF2H5 -806.0
ATP1B1 -787.0
RPS11 -773.0
VPS45 -724.0
BTRC -717.0
CALM1 -694.0
ADCY8 -691.0
UBB -665.0
EEF2 -651.0
PSMA4 -648.0
S1PR1 -631.0
NDC1 -624.0
IFNA21 -615.0
RPS14 -538.0
NFKB1 -487.0
TBP -483.0
MAP2K4 -452.0
KEAP1 -351.0
MYO5A -350.0
PRKACB -341.0
IL17RA -324.0
CHMP3 -318.0
DVL3 -317.0
DYNC1I1 -230.0
SNRPD1 -139.0
RAB5A -138.0
XRCC5 -134.0
RPS27A -126.0
H4C12 -107.0
ARPC5 -95.0
CBLL1 -90.0
PACS1 -87.0
HLA-F 41.0
PARP8 62.0
TAF9 76.0
VTA1 109.0
RPLP1 175.0
GTF2H4 183.0
RPS7 193.0
POLR2C 198.0
PTK2 209.0
HLA-B 227.0
ARPC2 246.0
TAB1 262.0
NFKB2 284.0
TUBB2A 305.0
MYO1C 322.0
H4C1 323.0
RPL12 342.0
BCL2L1 380.0
H2AC16 397.0
PLCG1 428.0
ZDHHC11 433.0
RIPK2 437.0
TXNRD1 473.0
POLR2E 503.0
CYBA 541.0
NELFA 565.0
UBE2I 578.0
TGFB1 602.0
GNG4 613.0
YWHAB 626.0
CANX 654.0
RPN1 664.0
HGS 680.0
CTNNB1 682.0
H4C8 685.0
CORO1A 700.0
ADCY7 771.0
AP1S3 785.0
CUL5 797.0
SEC23A 830.0
PARP10 836.0
LIG4 837.0
H2BC17 842.0
PRKAR1B 854.0
RPS19 887.0
VPS11 901.0
GTF2F1 936.0
SNRPG 982.0
PSMD11 1023.0
SLC25A4 1073.0
JAK1 1094.0
GEMIN5 1111.0
CPSF4 1150.0
PARP16 1175.0
NUP43 1180.0
AKT3 1209.0
DVL2 1256.0
CDK9 1265.0
UBE2N 1276.0
RPL15 1283.0
PSMB4 1285.0
RPL28 1298.0
PSMA5 1304.0
UBAP1 1353.0
VPS37A 1354.0
CCNT1 1385.0
MGAT5 1386.0
RPL22 1475.0
CD163 1480.0
ELOA2 1535.0
MAP2K2 1555.0
PTPN6 1567.0
DAXX 1573.0
YWHAH 1579.0
PSMC4 1596.0
HLA-E 1609.0
ANO10 1651.0
CHMP2B 1663.0
PTGES3 1666.0
RNF213 1699.0
NCKIPSD 1736.0
H3C11 1739.0
CYFIP2 1788.0
ITGA4 1798.0
NLRP3 1824.0
ADCY3 1855.0
SYT2 1938.0
ATP1A3 1949.0
BRK1 1967.0
NRP1 1968.0
G3BP2 2083.0
PSME2 2084.0
ADCY9 2100.0
HCK 2116.0
ABI1 2119.0
RPL41 2146.0
RPL37 2151.0
RPS27 2171.0
AP2B1 2173.0
KPNA5 2311.0
IFNA13 2350.0
RPS15A 2354.0
POLR2D 2370.0
ZDHHC5 2400.0
SEC24B 2402.0
TAF4B 2428.0
NUP85 2430.0
H3C10 2461.0
KPNA3 2494.0
PARP4 2523.0
H4C5 2528.0
RPS29 2538.0
SH3GL2 2570.0
RPS3 2573.0
RPL34 2588.0
GNB4 2592.0
KPNA2 2633.0
DAD1 2645.0
AP1S1 2682.0
GNG5 2685.0
FKBP1A 2696.0
TUBA3D 2717.0
VPS18 2729.0
IFNA14 2763.0
MAP2K3 2764.0
RPL27A 2771.0
PRKACA 2782.0
GATAD2A 2784.0
NUP205 2803.0
PSMD12 2806.0
DOCK1 2839.0
CYFIP1 2859.0
TAF12 2897.0
PLCG2 3024.0
YWHAQ 3040.0
CAV1 3046.0
GNAI2 3078.0
WIPF1 3085.0
GNG8 3100.0
ACTB 3141.0
NUP133 3158.0
POLR2F 3184.0
XRCC4 3215.0
NUP54 3235.0
MYH9 3240.0
NUP210 3259.0
LARP1 3292.0
GNG7 3330.0
DOCK2 3373.0
IFNA8 3393.0
TUBB6 3395.0
RPS3A 3411.0
SAP30L 3412.0
EGFR 3462.0
ATP1A1 3477.0
MAPK8 3528.0
ADAM17 3597.0
RPS13 3598.0
IFNAR1 3650.0
POLR2J 3674.0
PSMD14 3679.0
DDOST 3732.0
H3C2 3733.0
MAP2K7 3747.0
RPS2 3762.0
NCOR1 3766.0
ARPC1B 3767.0
IRAK2 3838.0
VEGFA 3867.0
SDC2 3882.0
DDX5 3974.0
AGRN 4019.0
TRIM28 4029.0
IL1R1 4036.0
RPL6 4045.0
RPS25 4057.0
H4C4 4097.0
SFTPD 4115.0
MAP2K1 4145.0
NEDD4L 4151.0
PRKACG 4191.0
RPL26L1 4216.0
RPS24 4241.0
GNB2 4244.0
CD247 4275.0
COMT 4292.0
MTA1 4312.0
GTF2E2 4313.0
GNG12 4316.0
MEFV 4337.0
TAF7 4352.0
PSMB6 4375.0
TMPRSS2 4409.0
RNF135 4432.0
CCNK 4453.0
SIGMAR1 4456.0
ADCY4 4464.0
MTA3 4544.0
RPL22L1 4607.0
RCAN3 4613.0
GNG2 4615.0
REST 4619.0
PYCARD 4698.0
RPL18A 4718.0
MET 4724.0
SH3GL3 4783.0
NUP35 4792.0
CD79B 4803.0
RPL38 4807.0
WASF3 4820.0
H4C16 4865.0
SNRPF 4945.0
VPS39 4963.0
GUCY2C 5001.0
IL17A 5053.0
SMN1 5068.5
SMN2 5068.5
TUBB1 5090.0
ANTXR1 5097.0
RPL9 5114.0
NFKBIA 5179.0
ANO9 5186.0
RNMT 5190.0
IMPDH2 5215.0
BLNK 5241.0
IFNA6 5324.0
MVB12B 5342.0
ST6GALNAC3 5346.0
SDC1 5357.0
VAV2 5364.0
CHMP2A 5400.0
H4C6 5430.0
HMOX1 5467.0
NUP62 5471.0
UBE2V1 5534.0
SEM1 5631.0
TLR1 5706.0
SUPT4H1 5721.0
MAN1B1 5726.0
NT5E 5744.0
MYO10 5753.0
ZDHHC8 5808.0
PLK2 5860.0
TRAF3 5900.0
C3 5919.0
DYNLL2 5999.0
TCEA1 6002.0
SSRP1 6003.0
TUBA4B 6042.0
SYK 6059.0
ST3GAL3 6070.0
GNAI1 6095.0
HAVCR1 6096.0
IL17RC 6132.0
RPL39L 6167.0
PSMD4 6169.0
RPL3 6195.0
CCR5 6200.0
CD28 6211.0
FXYD2 6227.0
ST6GAL1 6241.0
SV2A 6278.0
UBA52 6282.0
SERPINE1 6311.0
TKFC 6326.0
ST6GALNAC4 6344.0
TUBB4A 6369.0
PTPN11 6400.0
RPL13A 6422.5
NOXO1 6429.0
DPEP1 6478.0
CEBPD 6510.0
FXYD3 6525.0
GNG13 6596.0
BAIAP2 6655.0
TUBA4A 6664.0
SV2B 6746.0
DUSP16 6752.0
PSMD5 6795.0
CD4 6893.0
SDC4 6908.0
TUBB3 6928.0
FXYD7 6944.0
RELA 6961.0
PRKAR2A 7000.0
CD9 7004.0
GPC2 7075.0
CDH1 7228.0
KPNA7 7243.0
STX1B 7302.0
IFNA16 7312.0
FCGR2A 7397.0
ANO2 7408.0
PRKAR2B 7419.0
IKBKE 7420.0
LTF 7473.0
GNGT1 7502.0
ATP1A4 7583.0
ANO5 7597.0
WIPF3 7773.0
CD8B 7786.0
CTSL 7791.0
SRC 7873.0
C3AR1 7878.0
TUBB2B 7929.0
ADCY1 7939.0
ANO1 7957.0
ATP1B2 7966.0
MASP2 8002.0
NOS2 8016.0
TUBA8 8140.0
MASP1 8185.0
HSPG2 8222.0
POM121C 8315.0
CD79A 8385.0
DPEP2 8455.0
RPL29 8479.0
TLR9 8552.0
ADCY6 8590.0
ADCY5 8848.0
FXYD6 8909.0
APOBEC3G 8926.0
ANO7 8963.0
CD3G 9119.0
SDC3 9139.0
GGT5 9172.0
PKLR 9206.0
AP1M2 9227.0
CRB3 9323.0
LCK 9450.0
PSMB11 9506.0
MBL2 9549.0
TUBB8 9559.0
ST6GALNAC2 9794.0
ZBP1 9866.0
IFNA2 9991.0
GNG11 10008.0
IL1A 10020.0
GNB3 10044.0
FXYD4 10199.0
IFNA7 10246.0
SFN 10291.0
RPL3L 10336.0
ATP1A2 10367.0
GNGT2 10448.0
PDCD1 10567.0


REACTOME_DNA_REPLICATION

REACTOME_DNA_REPLICATION
1113
set REACTOME_DNA_REPLICATION
setSize 178
pANOVA 4.13e-15
s.dist -0.341
p.adjustANOVA 7.53e-13



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
PSMB7 -10651.0
PSMC6 -10621.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
PSMD2 -10209.0
H2AC20 -10208.0
H2BC15 -10189.0
FZR1 -10150.0
PSMC2 -10087.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
PSMB7 -10651.0
PSMC6 -10621.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
PSMD2 -10209.0
H2AC20 -10208.0
H2BC15 -10189.0
FZR1 -10150.0
PSMC2 -10087.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
MCM5 -9953.0
PRIM2 -9944.0
LIG1 -9941.0
PSMA3 -9831.0
ORC4 -9685.0
CCNE2 -9649.0
PSMB8 -9616.0
PSME1 -9420.0
H2BC26 -9346.0
PSMC5 -9310.0
H2BC4 -9285.0
ANAPC16 -9057.0
PSMA8 -9037.0
H2BC9 -9020.5
H3C7 -9020.5
PRIM1 -8994.0
KPNB1 -8945.0
KPNA1 -8859.0
CDC23 -8726.0
PSME3 -8645.0
H2BC3 -8572.0
PSMD3 -8488.0
H4C3 -8451.0
H2AC6 -8428.0
PCNA -8301.0
UBC -8277.0
POLD3 -8233.0
H2BC10 -8174.0
ANAPC7 -8113.0
PSMD6 -8047.0
CDK2 -7826.0
H4C11 -7658.0
RFC3 -7597.0
H2BC13 -7580.0
PSMB10 -7549.0
H3C1 -7492.0
PSMD7 -7470.0
FEN1 -7452.0
CDC16 -7384.0
PSMB5 -7376.0
POLE4 -7340.0
H2BC5 -7339.0
CDC26 -7245.0
RFC1 -7068.0
PSMB2 -7000.0
PSMB9 -6985.0
PSMD9 -6972.0
MCM8 -6756.0
POLA2 -6677.0
SKP1 -6672.0
GINS3 -6647.0
CCNA2 -6534.0
H2BC1 -6434.0
POLD2 -6366.0
ANAPC5 -6314.0
ORC3 -6201.0
UBE2E1 -6123.0
PSMC3 -6093.0
SKP2 -5945.0
PSMD13 -5903.0
UBE2S -5833.0
GINS2 -5683.0
RFC4 -5573.0
H3-3B -5536.0
CCNE1 -5513.0
H2BC8 -5414.0
H3C4 -5404.0
H3-3A -5377.0
PSMA2 -5113.0
PSMD8 -5084.0
H2AC4 -4647.0
ORC2 -4586.0
PSMA1 -4584.0
H3C8 -4535.0
MCM10 -4516.0
POLD4 -4479.0
H2BC11 -4063.0
CDC27 -4048.0
RBX1 -4039.0
PSMB3 -4011.0
PSME4 -3807.0
GINS1 -3795.0
DBF4 -3726.0
ANAPC2 -3595.0
POLE -3565.0
H4C13 -3564.0
ANAPC10 -3558.0
PSMB1 -3117.0
CUL1 -2987.0
ORC1 -2801.0
PSMA7 -2759.0
PSMF1 -2512.0
H4C2 -2432.0
CDC6 -2240.0
RPA1 -2002.0
H2AZ2 -1872.0
ANAPC11 -1849.0
RFC5 -1846.0
PSMC1 -1839.0
PSMA6 -1800.0
GINS4 -1375.0
DNA2 -1113.0
H2AC8 -1109.0
H2AJ -963.0
CCNA1 -948.0
PSMD1 -818.0
MCM6 -758.0
CDT1 -686.0
MCM2 -674.0
UBB -665.0
PSMA4 -648.0
ORC6 -370.0
ANAPC4 -298.0
RPS27A -126.0
H4C12 -107.0
POLE3 87.0
H4C1 323.0
POLE2 373.0
MCM3 586.0
H4C8 685.0
H2BC17 842.0
H2AX 876.0
GMNN 1002.0
PSMD11 1023.0
RPA3 1184.0
POLD1 1233.0
PSMB4 1285.0
PSMA5 1304.0
PSMC4 1596.0
H3C11 1739.0
KPNA6 1747.0
RFC2 1966.0
PSME2 2084.0
RPA2 2309.0
CDC45 2313.0
MCM7 2427.0
H3C10 2461.0
H4C5 2528.0
MCM4 2571.0
UBE2D1 2677.0
PSMD12 2806.0
ANAPC1 2923.0
PSMD14 3679.0
H3C2 3733.0
H4C4 4097.0
PSMB6 4375.0
H2AZ1 4397.0
CDC7 4757.0
H4C16 4865.0
ORC5 5159.0
H4C6 5430.0
SEM1 5631.0
ANAPC15 6148.0
PSMD4 6169.0
UBA52 6282.0
PSMD5 6795.0
UBE2C 8787.0
PSMB11 9506.0


REACTOME_CELL_CYCLE_CHECKPOINTS

REACTOME_CELL_CYCLE_CHECKPOINTS
1120
set REACTOME_CELL_CYCLE_CHECKPOINTS
setSize 284
pANOVA 1.29e-14
s.dist -0.266
p.adjustANOVA 2.11e-12



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
PSMB7 -10651.0
PSMC6 -10621.0
H2BC6 -10375.0
H4C9 -10304.0
H2BC12 -10245.0
DSN1 -10243.0
KIF2B -10210.0
PSMD2 -10209.0
BRCA1 -10206.0
H2BC15 -10189.0
PSMC2 -10087.0
H2BC7 -10035.5
H2BC21 -10020.0
MCM5 -9953.0
PSMA3 -9831.0
ORC4 -9685.0
CCNE2 -9649.0
PSMB8 -9616.0
PMF1 -9524.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
PSMB7 -10651.0
PSMC6 -10621.0
H2BC6 -10375.0
H4C9 -10304.0
H2BC12 -10245.0
DSN1 -10243.0
KIF2B -10210.0
PSMD2 -10209.0
BRCA1 -10206.0
H2BC15 -10189.0
PSMC2 -10087.0
H2BC7 -10035.5
H2BC21 -10020.0
MCM5 -9953.0
PSMA3 -9831.0
ORC4 -9685.0
CCNE2 -9649.0
PSMB8 -9616.0
PMF1 -9524.0
CCNB2 -9510.0
HUS1 -9493.0
PSME1 -9420.0
KIF18A -9410.0
CLASP2 -9395.0
H2BC26 -9346.0
PSMC5 -9310.0
NUP37 -9289.0
H2BC4 -9285.0
YWHAZ -9228.0
RNF8 -9099.0
ANAPC16 -9057.0
PSMA8 -9037.0
H2BC9 -9020.5
CENPM -8958.0
DYNLL1 -8928.0
CDC23 -8726.0
EXO1 -8718.0
CENPH -8650.0
PSME3 -8645.0
SGO2 -8632.0
H2BC3 -8572.0
PSMD3 -8488.0
CENPT -8464.0
H4C3 -8451.0
KIF2C -8448.0
BUB1B -8413.0
NDE1 -8382.0
MAPRE1 -8365.0
UBC -8277.0
RMI2 -8269.0
UBE2V2 -8249.0
H2BC10 -8174.0
SEH1L -8137.0
NUP98 -8136.0
KAT5 -8114.0
ANAPC7 -8113.0
PSMD6 -8047.0
RAD9A -8023.0
NUP107 -7996.0
CDK2 -7826.0
MRE11 -7695.0
H4C11 -7658.0
CDCA8 -7604.0
RFC3 -7597.0
H2BC13 -7580.0
PSMB10 -7549.0
PSMD7 -7470.0
CDC16 -7384.0
PSMB5 -7376.0
HERC2 -7359.0
NBN -7344.0
H2BC5 -7339.0
YWHAG -7293.0
CDC25C -7260.0
CDC26 -7245.0
CENPQ -7210.0
BLM -7176.0
NUDC -7128.0
RNF168 -7116.0
DYNC1LI1 -7041.0
PSMB2 -7000.0
PSMB9 -6985.0
PSMD9 -6972.0
CDC25A -6793.0
PHF20 -6767.0
MCM8 -6756.0
BABAM1 -6706.0
SPC25 -6632.0
CCNA2 -6534.0
NUP160 -6475.0
SEC13 -6469.0
NDEL1 -6443.0
H2BC1 -6434.0
CDKN1B -6381.0
CLIP1 -6364.0
ANAPC5 -6314.0
PAFAH1B1 -6282.0
ORC3 -6201.0
DYNC1LI2 -6196.0
UBE2E1 -6123.0
KNTC1 -6122.0
PIAS4 -6095.0
PSMC3 -6093.0
PSMD13 -5903.0
ABRAXAS1 -5893.0
CDKN2A -5841.0
UBE2S -5833.0
ZWILCH -5742.0
MIS12 -5727.0
KNL1 -5659.0
COP1 -5635.0
RFC4 -5573.0
CCNE1 -5513.0
H2BC8 -5414.0
RANGAP1 -5347.0
PPP2R5A -5281.0
ZW10 -5219.0
ATRIP -5204.0
BUB1 -5121.0
PSMA2 -5113.0
PSMD8 -5084.0
TOPBP1 -5020.0
DYNC1H1 -5010.0
NSD2 -4972.0
NSL1 -4893.0
DYNC1I2 -4740.0
CENPE -4657.0
CENPF -4587.0
ORC2 -4586.0
PSMA1 -4584.0
MCM10 -4516.0
RMI1 -4357.0
RBBP8 -4231.0
WRN -4227.0
CENPA -4213.0
H2BC11 -4063.0
CDC27 -4048.0
GTSE1 -4035.0
INCENP -4030.0
PSMB3 -4011.0
SKA2 -3991.0
PPP2R1B -3830.0
PSME4 -3807.0
DBF4 -3726.0
PPP2R5E -3697.0
TP53BP1 -3633.0
ANAPC2 -3595.0
H4C13 -3564.0
ANAPC10 -3558.0
KIF2A -3457.0
XPO1 -3414.0
PSMB1 -3117.0
TOP3A -3093.0
ORC1 -2801.0
MAD1L1 -2784.0
PSMA7 -2759.0
MDM4 -2718.0
ATM -2668.0
CKAP5 -2548.0
PSMF1 -2512.0
CLSPN -2497.0
H4C2 -2432.0
PPP2R1A -2279.0
CDC6 -2240.0
RPA1 -2002.0
ITGB3BP -1875.0
ANAPC11 -1849.0
RFC5 -1846.0
PSMC1 -1839.0
PSMA6 -1800.0
NUF2 -1758.0
RHNO1 -1742.0
B9D2 -1720.0
CDKN1A -1607.0
CENPO -1579.0
AHCTF1 -1446.0
SPDL1 -1326.0
CENPC -1213.0
RANBP2 -1170.0
DNA2 -1113.0
CCNA1 -948.0
PSMD1 -818.0
YWHAE -811.0
MCM6 -758.0
NDC80 -719.0
PLK1 -706.0
MCM2 -674.0
UBB -665.0
PSMA4 -648.0
SPC24 -642.0
PPP2R5C -627.0
ORC6 -370.0
RAD17 -303.0
ANAPC4 -298.0
CENPN -295.0
PPP2CB -279.0
DYNC1I1 -230.0
ATR -207.0
RPS27A -126.0
H4C12 -107.0
RAD1 -102.0
PPP2CA -76.0
BARD1 -51.0
CLASP1 37.0
AURKB 55.0
MDM2 136.0
CENPP 177.0
RAD9B 312.0
H4C1 323.0
PPP2R5D 498.0
MCM3 586.0
WEE1 588.0
SKA1 603.0
YWHAB 626.0
H4C8 685.0
H2BC17 842.0
H2AX 876.0
CHEK2 921.0
CENPL 945.0
PSMD11 1023.0
NUP43 1180.0
RPA3 1184.0
BRIP1 1255.0
UBE2N 1276.0
PSMB4 1285.0
PSMA5 1304.0
TAOK1 1373.0
BABAM2 1393.0
MAD2L1 1519.0
ZWINT 1577.0
YWHAH 1579.0
PSMC4 1596.0
CENPS 1636.0
CENPK 1845.0
RFC2 1966.0
PSME2 2084.0
RPS27 2171.0
BUB3 2174.0
BIRC5 2299.0
RPA2 2309.0
CDC45 2313.0
CHEK1 2332.0
MCM7 2427.0
NUP85 2430.0
H4C5 2528.0
MCM4 2571.0
UBE2D1 2677.0
PSMD12 2806.0
ANAPC1 2923.0
MDC1 2996.0
YWHAQ 3040.0
NUP133 3158.0
PPP2R5B 3218.0
CDC20 3609.0
PSMD14 3679.0
PKMYT1 3727.0
UIMC1 3738.0
H4C4 4097.0
CCNB1 4274.0
PSMB6 4375.0
SGO1 4410.0
RCC2 4422.0
PPP1CC 4750.0
CDC7 4757.0
H4C16 4865.0
CDK1 4923.0
CENPU 5042.0
ORC5 5159.0
ZNF385A 5162.0
RAD50 5232.0
H4C6 5430.0
SEM1 5631.0
TP53 5757.0
PCBP4 5764.0
DYNLL2 5999.0
ANAPC15 6148.0
PSMD4 6169.0
UBA52 6282.0
PSMD5 6795.0
H3-4 7087.0
UBE2C 8787.0
PSMB11 9506.0
SFN 10291.0


REACTOME_CHROMATIN_MODIFYING_ENZYMES

REACTOME_CHROMATIN_MODIFYING_ENZYMES
558
set REACTOME_CHROMATIN_MODIFYING_ENZYMES
setSize 252
pANOVA 5.53e-14
s.dist -0.275
p.adjustANOVA 8.25e-12



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
H2AC12 -10676.0
MEAF6 -10616.0
ASH2L -10434.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
MRGBP -10106.0
ATXN7L3 -10061.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
H2AC12 -10676.0
MEAF6 -10616.0
ASH2L -10434.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
MRGBP -10106.0
ATXN7L3 -10061.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
SMARCD1 -9882.0
KAT8 -9757.0
EP300 -9652.0
MCRS1 -9509.0
H2AC15 -9502.0
KDM3A -9475.0
ATXN7 -9430.0
H2BC26 -9346.0
ARID2 -9334.0
H2BC4 -9285.0
SGF29 -9259.0
GPS2 -9206.0
NSD3 -9093.0
ARID4A -9035.0
H2BC9 -9020.5
H3C7 -9020.5
KMT2C -8999.0
H2AC13 -8863.0
KANSL2 -8850.0
TADA1 -8840.0
AEBP2 -8793.0
SMARCD2 -8686.0
SUZ12 -8594.0
MSL2 -8589.0
NCOA2 -8586.0
H2BC3 -8572.0
KDM2A -8479.0
H4C3 -8451.0
H2AC6 -8428.0
SAP30 -8418.0
BRWD1 -8175.0
H2BC10 -8174.0
PRMT1 -8128.0
KAT5 -8114.0
SAP18 -8083.0
KMT5A -8065.0
KDM6B -8060.0
SMARCE1 -8044.0
KMT5B -7973.0
JMJD6 -7900.0
TAF10 -7853.0
HDAC10 -7850.0
KAT6A -7825.0
ARID4B -7690.0
H4C11 -7658.0
TADA2A -7630.0
H2BC13 -7580.0
ENY2 -7523.0
H3C1 -7492.0
H2AC21 -7400.0
H2BC5 -7339.0
ELP4 -7330.0
KAT2B -7302.0
SUPT7L -7291.0
RBBP4 -7271.0
SUV39H2 -7218.0
KDM1A -7160.0
KDM4C -7122.0
MTA2 -7100.0
ELP5 -7034.0
TADA3 -7021.0
GATAD2B -7010.0
SETD1A -6967.0
ZZZ3 -6840.0
PHF20 -6767.0
MSL1 -6563.0
ARID5B -6505.0
SMARCC2 -6480.0
H2BC1 -6434.0
H2AC25 -6343.0
KMT2A -6224.0
PHF21A -6152.0
NCOR2 -6078.0
VPS72 -5939.0
HDAC1 -5913.0
BRPF1 -5911.0
HAT1 -5879.0
DPY30 -5759.0
JADE2 -5694.0
MBD3 -5490.0
H2BC8 -5414.0
PRMT6 -5405.0
H3C4 -5404.0
USP22 -5401.0
BRMS1 -5339.0
SUPT3H -5196.0
PBRM1 -5162.0
RIOX2 -5136.0
NSD2 -4972.0
ARID1B -4960.0
COPRS -4871.0
SETD2 -4866.0
SUPT20H -4810.0
H2AC4 -4647.0
WDR77 -4626.0
BRD1 -4540.0
H3C8 -4535.0
PRMT3 -4524.0
SUDS3 -4430.0
TBL1XR1 -4414.0
HDAC2 -4377.0
CLOCK -4359.0
KDM5B -4355.0
ARID1A -4245.0
SETD6 -4090.0
SMYD2 -4076.0
H2BC11 -4063.0
WDR5 -4056.0
H2AC1 -3983.0
H4C13 -3564.0
NCOA1 -3556.0
CHD3 -3438.0
RCOR1 -3356.0
HMG20B -3275.0
H2AC17 -3211.0
SAP130 -3168.0
EPC1 -3053.0
DOT1L -3008.0
EED -2898.0
ELP2 -2866.0
KDM4D -2844.0
KMT2E -2841.0
YEATS4 -2805.0
HDAC3 -2723.0
SMARCB1 -2643.0
KANSL1 -2593.0
SETD3 -2540.0
EZH2 -2496.0
H4C2 -2432.0
JAK2 -2403.0
CARM1 -2380.0
PRMT7 -2361.0
EHMT2 -2233.0
RBBP5 -2037.0
H2AZ2 -1872.0
EP400 -1729.0
SETDB2 -1679.0
CREBBP -1603.0
ELP3 -1498.0
ING3 -1436.0
CHD4 -1434.0
ATF7IP -1384.0
RUVBL1 -1380.0
KANSL3 -1357.0
H2AC11 -1249.0
ING5 -1169.0
H2AC8 -1109.0
SMARCA4 -1103.0
ASH1L -1089.0
KAT6B -992.0
H2AJ -963.0
MBIP -831.0
TAF6L -707.0
BRD8 -683.0
SETD1B -490.0
NFKB1 -487.0
PAX3 -263.0
TRRAP -217.0
H4C12 -107.0
TAF9 76.0
MECOM 161.0
MORF4L1 216.0
NFKB2 284.0
KMT2D 302.0
H4C1 323.0
ELP1 326.0
H2AC16 397.0
H4C8 685.0
SMARCA2 828.0
H2BC17 842.0
DR1 860.0
H2AX 876.0
DMAP1 895.0
ACTL6A 1091.0
NSD1 1098.0
KAT2A 1331.0
KAT7 1362.0
SMYD3 1388.0
CDK4 1550.0
ELP6 1629.0
KDM3B 1655.0
PRDM9 1695.0
H3C11 1739.0
RUVBL2 1772.0
PHF2 1884.0
KDM2B 2204.0
YEATS2 2247.0
KDM4A 2264.0
TAF5L 2364.0
H3C10 2461.0
BRPF3 2474.0
H4C5 2528.0
KMT5C 2723.0
GATAD2A 2784.0
TAF12 2897.0
ACTB 3141.0
EHMT1 3168.0
KDM5A 3205.0
CCND1 3284.0
ATF2 3306.0
SMARCC1 3307.0
KDM4B 3377.0
SAP30L 3412.0
DNMT3A 3442.0
PRMT5 3698.0
H3C2 3733.0
RPS2 3762.0
NCOR1 3766.0
JADE1 3925.0
H4C4 4097.0
PADI1 4207.0
MTA1 4312.0
H2AZ1 4397.0
MTA3 4544.0
REST 4619.0
TADA2B 4665.0
H4C16 4865.0
ACTL6B 5107.0
PADI4 5128.0
KDM1B 5343.0
SETDB1 5370.0
H4C6 5430.0
ING4 5494.0
KDM7A 5777.0
SETD7 6074.0
PRDM16 6872.0
RELA 6961.0
PADI2 8498.0
PADI6 8778.0
SMARCD3 8913.0
KMT2B 9075.0
PADI3 10111.0


REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE
1082
set REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE
setSize 125
pANOVA 1.06e-13
s.dist 0.385
p.adjustANOVA 1.45e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
SPRR2E 10539
LCE3D 10514
LCE1F 10486
KLK14 10473
SPRR3 10403
KRT78 10127
KRT6C 10119
KRT84 10100
KRT79 10053
KRT14 9989
KRT83 9961
KRT72 9949
KRT4 9924
KRT80 9915
KRT82 9911
LCE6A 9833
KRT86 9746
KRT85 9665
LCE2B 9393
KRT3 9332

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SPRR2E 10539
LCE3D 10514
LCE1F 10486
KLK14 10473
SPRR3 10403
KRT78 10127
KRT6C 10119
KRT84 10100
KRT79 10053
KRT14 9989
KRT83 9961
KRT72 9949
KRT4 9924
KRT80 9915
KRT82 9911
LCE6A 9833
KRT86 9746
KRT85 9665
LCE2B 9393
KRT3 9332
TGM1 9203
KRT7 9167
KRT34 9147
KRT75 9106
KRT81 9099
PKP3 9084
KRT33B 9008
SPRR2A 8903
KRT28 8882
KRT6B 8810
CASP14 8681
KRT2 8649
ST14 8475
KRT5 8420
TGM5 8365
SPRR1B 8190
KLK13 8176
PCSK6 7909
SPRR1A 7883
KRT9 7830
DSG2 7749
KRT15 7748
LIPK 7736
KAZN 7652
PI3 7483
LELP1 7395
KLK8 7356
KRT1 7290
LCE3A 7067
KRT36 6949
KRT77 6803
KRT20 6683
KRT33A 6642
CELA2A 6584
JUP 6514
KRT8 6403
LCE2A 6357
PKP1 6287
KRT74 6276
LIPM 6221
KRT24 6209
DSP 6035
KRT6A 5747
KRT73 5535
KRT13 5299
IVL 5224
DSG4 5209
SPRR2G 5079
LCE5A 4988
PKP2 4948
LCE2C 4852
EVPL 4369
KRT12 4350
LCE1C 4302
KRT18 4283
RPTN 4048
KRT38 3976
KRT19 3953
KRT76 3921
CAPNS1 3700
DSC3 3438
KRT35 3400
DSG3 3378
KRT23 3371
PPL 3327
SPINK5 3233
SPRR2D 3123
LCE4A 2868
KRT71 2094
LCE3B 1856
CDSN 1829
KLK12 1803
KRT27 1635
LCE1A 1513
KRT40 1270
DSC2 1217
KRT16 926
TCHH 762
PKP4 -825
FURIN -867
LCE1E -902
KRT32 -1510
SPRR2F -1521
PERP -2289
PRSS8 -2887
LCE2D -3251
FLG -3512
KRT31 -4126
KRT39 -4331
LIPJ -4980
LCE3E -5246
KRT25 -5989
KRT26 -6735
CAPN1 -8050
LCE1B -8333
KLK5 -8399
KRT10 -8490
DSG1 -8532
KRT37 -8866
SPINK9 -9199
DSC1 -10188
LIPN -10284
SPINK6 -10292
KRT17 -11222
CSTA -11228


REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1

REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1
1272
set REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1
setSize 229
pANOVA 1.18e-13
s.dist -0.284
p.adjustANOVA 1.49e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
NFE2 -11221.0
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
IL3 -10796.0
H2AC14 -10727.0
PSMB7 -10651.0
PSMC6 -10621.0
SPI1 -10569.0
ASH2L -10434.0
MIR27A -10381.0
H2BC6 -10375.0
GP1BA -10343.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
MOV10 -10287.0
H2BC12 -10245.0
PSMD2 -10209.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NFE2 -11221.0
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
IL3 -10796.0
H2AC14 -10727.0
PSMB7 -10651.0
PSMC6 -10621.0
SPI1 -10569.0
ASH2L -10434.0
MIR27A -10381.0
H2BC6 -10375.0
GP1BA -10343.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
MOV10 -10287.0
H2BC12 -10245.0
PSMD2 -10209.0
H2AC20 -10208.0
H2BC15 -10189.0
TAL1 -10125.0
PSMC2 -10087.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
CSNK2A2 -9986.0
SMARCD1 -9882.0
PSMA3 -9831.0
SOCS3 -9829.0
GATA3 -9812.0
PCGF5 -9731.0
CDK6 -9698.0
EP300 -9652.0
PSMB8 -9616.0
PSME1 -9420.0
H2BC26 -9346.0
ARID2 -9334.0
PSMC5 -9310.0
H2BC4 -9285.0
TCF12 -9243.0
ELF1 -9151.0
MYB -9069.0
PSMA8 -9037.0
H2BC9 -9020.5
H3C7 -9020.5
KMT2C -8999.0
BMI1 -8777.0
SMARCD2 -8686.0
SIN3A -8665.0
PSME3 -8645.0
GATA2 -8618.0
H2BC3 -8572.0
PSMD3 -8488.0
H4C3 -8451.0
H2AC6 -8428.0
UBC -8277.0
RUNX1 -8234.0
H2BC10 -8174.0
PRMT1 -8128.0
PSMD6 -8047.0
SMARCE1 -8044.0
LIFR -7997.0
CBFB -7940.0
YAF2 -7861.0
CSNK2B -7734.0
SIN3B -7729.0
TNRC6B -7724.0
MNAT1 -7673.0
H4C11 -7658.0
H2BC13 -7580.0
AGO4 -7579.0
PSMB10 -7549.0
CCNH -7537.0
H3C1 -7492.0
PSMD7 -7470.0
ITCH -7429.0
PSMB5 -7376.0
H2BC5 -7339.0
KAT2B -7302.0
PSMB2 -7000.0
PSMB9 -6985.0
PSMD9 -6972.0
SETD1A -6967.0
SOCS4 -6784.0
RYBP -6779.0
TNFRSF18 -6753.0
CBX8 -6705.0
CCND2 -6682.0
LMO2 -6539.0
SMARCC2 -6480.0
H2BC1 -6434.0
KMT2A -6224.0
PSMC3 -6093.0
HDAC1 -5913.0
PSMD13 -5903.0
DPY30 -5759.0
RUNX2 -5688.0
GPAM -5596.0
ABL1 -5559.0
H3-3B -5536.0
PML -5486.0
AUTS2 -5467.0
H2BC8 -5414.0
PRMT6 -5405.0
H3C4 -5404.0
H3-3A -5377.0
CDK7 -5280.0
CTSK -5203.0
PBRM1 -5162.0
PSMA2 -5113.0
CBX6 -5107.0
PSMD8 -5084.0
ARID1B -4960.0
RNF2 -4904.0
H2AC4 -4647.0
PSMA1 -4584.0
H3C8 -4535.0
NR4A3 -4475.0
TJP1 -4314.0
ARID1A -4245.0
H2BC11 -4063.0
WDR5 -4056.0
PSMB3 -4011.0
PSME4 -3807.0
CBX4 -3688.0
H4C13 -3564.0
PSMB1 -3117.0
AGO3 -3073.0
PHC2 -3014.0
KMT2E -2841.0
PSMA7 -2759.0
SMARCB1 -2643.0
THBS1 -2605.0
PSMF1 -2512.0
H4C2 -2432.0
RBBP5 -2037.0
H2AZ2 -1872.0
PSMC1 -1839.0
PSMA6 -1800.0
IL2RA -1680.0
CREBBP -1603.0
ZFPM1 -1594.0
CR1 -1589.0
LDB1 -1228.0
H2AC8 -1109.0
SMARCA4 -1103.0
H2AJ -963.0
CBX2 -849.0
PSMD1 -818.0
RING1 -740.0
UBB -665.0
PSMA4 -648.0
SETD1B -490.0
TNRC6A -436.0
SCMH1 -327.0
RPS27A -126.0
H4C12 -107.0
NFATC2 -27.0
PRKCB 3.0
AGO2 199.0
KMT2D 302.0
H4C1 323.0
ELF2 371.0
AGO1 376.0
KCTD6 430.0
YAP1 465.0
ESR1 559.0
H4C8 685.0
CCND3 726.0
SMARCA2 828.0
H2BC17 842.0
H2AX 876.0
PSMD11 1023.0
ACTL6A 1091.0
RSPO3 1145.0
PSMB4 1285.0
PSMA5 1304.0
PSMC4 1596.0
HIPK2 1642.0
PHC3 1727.0
H3C11 1739.0
TCF3 1961.0
PSME2 2084.0
PF4 2093.0
LGALS3 2320.0
H3C10 2461.0
H4C5 2528.0
PSMD12 2806.0
AXIN1 3098.0
SERPINB13 3166.0
TNRC6C 3185.0
CCND1 3284.0
SMARCC1 3307.0
PRKCQ 3513.0
CSNK2A1 3638.0
PSMD14 3679.0
H3C2 3733.0
H4C4 4097.0
PSMB6 4375.0
H2AZ1 4397.0
MYL9 4856.0
H4C16 4865.0
ACTL6B 5107.0
H4C6 5430.0
SEM1 5631.0
BLK 5838.0
LMO1 5962.0
PHC1 6131.0
PSMD4 6169.0
UBA52 6282.0
PTPN11 6400.0
CTSV 6447.0
IFNG 6483.0
OCLN 6561.0
PAX5 6665.0
PSMD5 6795.0
CTLA4 7210.0
TP73 7334.0
CTSL 7791.0
SRC 7873.0
ITGA2B 7936.0
SMARCD3 8913.0
KMT2B 9075.0
CSF2 9358.0
PSMB11 9506.0
CLDN5 9508.0
IL2 9975.0


REACTOME_NEGATIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION

REACTOME_NEGATIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION
853
set REACTOME_NEGATIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION
setSize 100
pANOVA 1.42e-13
s.dist -0.428
p.adjustANOVA 1.66e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
RRP8 -10241.0
H2AC20 -10208.0
POLR1E -10205.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
SAP30BP -10023.0
H2BC21 -10020.0
POLR1B -9824.0
MBD2 -9377.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
RRP8 -10241.0
H2AC20 -10208.0
POLR1E -10205.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
SAP30BP -10023.0
H2BC21 -10020.0
POLR1B -9824.0
MBD2 -9377.0
ERCC3 -9371.0
H2BC26 -9346.0
H2BC4 -9285.0
H2BC9 -9020.5
H3C7 -9020.5
TAF1B -8830.0
SIN3A -8665.0
H2BC3 -8572.0
H4C3 -8451.0
GTF2H3 -8449.0
H2AC6 -8428.0
SAP30 -8418.0
H2BC10 -8174.0
SAP18 -8083.0
ERCC2 -7814.0
SIN3B -7729.0
ARID4B -7690.0
GTF2H1 -7675.0
MNAT1 -7673.0
H4C11 -7658.0
H2BC13 -7580.0
CCNH -7537.0
H3C1 -7492.0
H2BC5 -7339.0
POLR1C -7120.0
BAZ2A -7059.0
POLR2H -6881.0
TAF1D -6750.0
DNMT1 -6562.0
DNMT3B -6553.0
POLR1G -6552.0
SIRT1 -6458.0
H2BC1 -6434.0
POLR2L -5972.0
HDAC1 -5913.0
POLR2K -5634.0
H3-3B -5536.0
H2BC8 -5414.0
H3C4 -5404.0
H3-3A -5377.0
CDK7 -5280.0
H2AC4 -4647.0
H3C8 -4535.0
SUDS3 -4430.0
HDAC2 -4377.0
H2BC11 -4063.0
H4C13 -3564.0
SAP130 -3168.0
POLR1H -2697.0
POLR1A -2555.0
H4C2 -2432.0
H2AZ2 -1872.0
H2AC8 -1109.0
H2AJ -963.0
GTF2H5 -806.0
TBP -483.0
SMARCA5 -420.0
TAF1A -129.0
H4C12 -107.0
GTF2H4 183.0
POLR1D 218.0
H4C1 323.0
POLR2E 503.0
H4C8 685.0
H2BC17 842.0
H2AX 876.0
UBTF 1426.0
H3C11 1739.0
POLR1F 1814.0
H3C10 2461.0
TAF1C 2477.0
H4C5 2528.0
POLR2F 3184.0
SAP30L 3412.0
H3C2 3733.0
H4C4 4097.0
H2AZ1 4397.0
H4C16 4865.0
H4C6 5430.0
TTF1 7232.0


REACTOME_HATS_ACETYLATE_HISTONES

REACTOME_HATS_ACETYLATE_HISTONES
551
set REACTOME_HATS_ACETYLATE_HISTONES
setSize 129
pANOVA 1.54e-13
s.dist -0.376
p.adjustANOVA 1.69e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
H2AC12 -10676.0
MEAF6 -10616.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
MRGBP -10106.0
ATXN7L3 -10061.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
KAT8 -9757.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
H2AC12 -10676.0
MEAF6 -10616.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
MRGBP -10106.0
ATXN7L3 -10061.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
KAT8 -9757.0
EP300 -9652.0
MCRS1 -9509.0
H2AC15 -9502.0
ATXN7 -9430.0
H2BC26 -9346.0
H2BC4 -9285.0
SGF29 -9259.0
H2BC9 -9020.5
H3C7 -9020.5
H2AC13 -8863.0
KANSL2 -8850.0
TADA1 -8840.0
MSL2 -8589.0
NCOA2 -8586.0
H2BC3 -8572.0
H4C3 -8451.0
H2AC6 -8428.0
H2BC10 -8174.0
KAT5 -8114.0
TAF10 -7853.0
KAT6A -7825.0
H4C11 -7658.0
TADA2A -7630.0
H2BC13 -7580.0
ENY2 -7523.0
H3C1 -7492.0
H2AC21 -7400.0
H2BC5 -7339.0
ELP4 -7330.0
KAT2B -7302.0
SUPT7L -7291.0
ELP5 -7034.0
TADA3 -7021.0
ZZZ3 -6840.0
PHF20 -6767.0
MSL1 -6563.0
H2BC1 -6434.0
H2AC25 -6343.0
VPS72 -5939.0
BRPF1 -5911.0
HAT1 -5879.0
JADE2 -5694.0
H2BC8 -5414.0
H3C4 -5404.0
USP22 -5401.0
SUPT3H -5196.0
SUPT20H -4810.0
H2AC4 -4647.0
BRD1 -4540.0
H3C8 -4535.0
CLOCK -4359.0
H2BC11 -4063.0
WDR5 -4056.0
H2AC1 -3983.0
H4C13 -3564.0
NCOA1 -3556.0
H2AC17 -3211.0
SAP130 -3168.0
EPC1 -3053.0
ELP2 -2866.0
YEATS4 -2805.0
KANSL1 -2593.0
H4C2 -2432.0
EP400 -1729.0
CREBBP -1603.0
ELP3 -1498.0
ING3 -1436.0
RUVBL1 -1380.0
KANSL3 -1357.0
H2AC11 -1249.0
ING5 -1169.0
H2AC8 -1109.0
KAT6B -992.0
MBIP -831.0
TAF6L -707.0
BRD8 -683.0
PAX3 -263.0
TRRAP -217.0
H4C12 -107.0
TAF9 76.0
MORF4L1 216.0
H4C1 323.0
ELP1 326.0
H2AC16 397.0
H4C8 685.0
H2BC17 842.0
DR1 860.0
DMAP1 895.0
ACTL6A 1091.0
KAT2A 1331.0
KAT7 1362.0
ELP6 1629.0
H3C11 1739.0
RUVBL2 1772.0
YEATS2 2247.0
TAF5L 2364.0
H3C10 2461.0
BRPF3 2474.0
H4C5 2528.0
TAF12 2897.0
ACTB 3141.0
ATF2 3306.0
H3C2 3733.0
JADE1 3925.0
H4C4 4097.0
TADA2B 4665.0
H4C16 4865.0
H4C6 5430.0
ING4 5494.0


REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION

REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION
437
set REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION
setSize 138
pANOVA 1.82e-13
s.dist -0.363
p.adjustANOVA 1.87e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
RRP8 -10241.0
H2AC20 -10208.0
POLR1E -10205.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
SAP30BP -10023.0
H2BC21 -10020.0
JARID2 -9908.0
POLR1B -9824.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
RRP8 -10241.0
H2AC20 -10208.0
POLR1E -10205.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
SAP30BP -10023.0
H2BC21 -10020.0
JARID2 -9908.0
POLR1B -9824.0
EP300 -9652.0
MBD2 -9377.0
ERCC3 -9371.0
H2BC26 -9346.0
H2BC4 -9285.0
H2BC9 -9020.5
H3C7 -9020.5
TAF1B -8830.0
AEBP2 -8793.0
SIN3A -8665.0
SUZ12 -8594.0
H2BC3 -8572.0
H4C3 -8451.0
GTF2H3 -8449.0
H2AC6 -8428.0
SAP30 -8418.0
H2BC10 -8174.0
SAP18 -8083.0
ERCC2 -7814.0
SIN3B -7729.0
ARID4B -7690.0
GTF2H1 -7675.0
MNAT1 -7673.0
H4C11 -7658.0
H2BC13 -7580.0
CCNH -7537.0
H3C1 -7492.0
H2BC5 -7339.0
KAT2B -7302.0
RBBP4 -7271.0
POLR1C -7120.0
TET2 -7104.0
MTA2 -7100.0
BAZ2A -7059.0
GATAD2B -7010.0
POLR2H -6881.0
TAF1D -6750.0
MTF2 -6719.0
DNMT1 -6562.0
DNMT3B -6553.0
POLR1G -6552.0
SIRT1 -6458.0
H2BC1 -6434.0
DEK -6397.0
POLR2L -5972.0
HDAC1 -5913.0
PHF1 -5862.0
POLR2K -5634.0
H3-3B -5536.0
MBD3 -5490.0
H2BC8 -5414.0
H3C4 -5404.0
H3-3A -5377.0
CDK7 -5280.0
TDG -4767.0
H2AC4 -4647.0
H3C8 -4535.0
SUDS3 -4430.0
HDAC2 -4377.0
H2BC11 -4063.0
BAZ1B -3951.0
H4C13 -3564.0
CHD3 -3438.0
SF3B1 -3274.0
SAP130 -3168.0
TET3 -2924.0
EED -2898.0
POLR1H -2697.0
GSK3B -2656.0
POLR1A -2555.0
EZH2 -2496.0
H4C2 -2432.0
EHMT2 -2233.0
H2AZ2 -1872.0
CHD4 -1434.0
ERCC6 -1248.0
H2AC8 -1109.0
H2AJ -963.0
CBX3 -932.0
GTF2H5 -806.0
TBP -483.0
SMARCA5 -420.0
DDX21 -396.0
TAF1A -129.0
H4C12 -107.0
GTF2H4 183.0
POLR1D 218.0
MYO1C 322.0
H4C1 323.0
POLR2E 503.0
H4C8 685.0
TET1 752.0
H2BC17 842.0
H2AX 876.0
KAT2A 1331.0
UBTF 1426.0
H3C11 1739.0
POLR1F 1814.0
UHRF1 2045.0
H3C10 2461.0
TAF1C 2477.0
H4C5 2528.0
GATAD2A 2784.0
MYBBP1A 3133.0
ACTB 3141.0
POLR2F 3184.0
SAP30L 3412.0
DNMT3A 3442.0
H3C2 3733.0
H4C4 4097.0
MTA1 4312.0
H2AZ1 4397.0
MTA3 4544.0
PHF19 4821.0
H4C16 4865.0
H4C6 5430.0
TTF1 7232.0
DNMT3L 8623.0


REACTOME_DEUBIQUITINATION

REACTOME_DEUBIQUITINATION
1000
set REACTOME_DEUBIQUITINATION
setSize 260
pANOVA 2.3e-13
s.dist -0.264
p.adjustANOVA 2.22e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
RAD23A -10762.0
H2AC14 -10727.0
H2AC12 -10676.0
TGFBR1 -10661.0
PSMB7 -10651.0
PSMC6 -10621.0
VCPIP1 -10387.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H2BC12 -10245.0
PSMD2 -10209.0
H2AC20 -10208.0
BRCA1 -10206.0
H2BC15 -10189.0
PSMC2 -10087.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
RAD23A -10762.0
H2AC14 -10727.0
H2AC12 -10676.0
TGFBR1 -10661.0
PSMB7 -10651.0
PSMC6 -10621.0
VCPIP1 -10387.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H2BC12 -10245.0
PSMD2 -10209.0
H2AC20 -10208.0
BRCA1 -10206.0
H2BC15 -10189.0
PSMC2 -10087.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
NOD1 -10009.0
UCHL3 -9976.0
BECN1 -9853.0
PSMA3 -9831.0
GATA3 -9812.0
WDR48 -9688.0
EP300 -9652.0
PSMB8 -9616.0
YY1 -9573.0
MCRS1 -9509.0
H2AC15 -9502.0
ATXN7 -9430.0
PSME1 -9420.0
SIAH2 -9404.0
H2BC26 -9346.0
PSMC5 -9310.0
H2BC4 -9285.0
PSMA8 -9037.0
H2BC9 -9020.5
H2AC13 -8863.0
TOMM70 -8822.0
TNFAIP3 -8695.0
PSME3 -8645.0
H2BC3 -8572.0
PSMD3 -8488.0
RCE1 -8445.0
H2AC6 -8428.0
RNF146 -8379.0
UBC -8277.0
H2BC10 -8174.0
ACTR5 -8146.0
MAT2B -8135.0
STAMBP -8122.0
SMAD3 -8098.0
USP19 -8077.0
USP13 -8054.0
PSMD6 -8047.0
USP47 -8019.0
CCP110 -8007.0
USP21 -7965.0
IFIH1 -7904.0
WDR20 -7859.0
TAF10 -7853.0
APC -7836.0
RHOT1 -7738.0
ASXL2 -7663.0
INO80 -7662.0
BIRC3 -7652.0
MBD5 -7614.0
H2BC13 -7580.0
TRAF2 -7574.0
PSMB10 -7549.0
PSMD7 -7470.0
JOSD1 -7449.0
SMAD4 -7434.0
STAM -7421.0
H2AC21 -7400.0
PSMB5 -7376.0
INO80D -7350.0
H2BC5 -7339.0
KAT2B -7302.0
RIPK1 -7072.0
TADA3 -7021.0
MAP3K7 -7012.0
PSMB2 -7000.0
PSMB9 -6985.0
PSMD9 -6972.0
VCP -6884.0
CDC25A -6793.0
BABAM1 -6706.0
CCNA2 -6534.0
BIRC2 -6460.0
H2BC1 -6434.0
H2AC25 -6343.0
STAMBPL1 -6115.0
PSMC3 -6093.0
TRIM4 -6020.0
SKP2 -5945.0
PSMD13 -5903.0
ABRAXAS1 -5893.0
USP30 -5713.0
DDB2 -5674.0
ACTR8 -5606.0
H2BC8 -5414.0
USP22 -5401.0
IDE -5400.0
INO80C -5235.0
RIGI -5177.0
PSMA2 -5113.0
USP37 -5085.0
PSMD8 -5084.0
BAP1 -5052.0
USP48 -5013.0
TNKS -4997.0
TNIP3 -4983.0
ARRB1 -4907.0
TNIP2 -4865.0
TNKS2 -4789.0
ZRANB1 -4669.0
H2AC4 -4647.0
PSMA1 -4584.0
PTEN -4562.0
YOD1 -4496.0
SUDS3 -4430.0
TRIM25 -4186.0
H2BC11 -4063.0
ADRM1 -4028.0
PSMB3 -4011.0
TRAF6 -3985.0
H2AC1 -3983.0
MAVS -3892.0
PSME4 -3807.0
NFRKB -3616.0
POLB -3527.0
USP3 -3327.0
USP34 -3242.0
RAD23B -3238.0
H2AC17 -3211.0
PSMB1 -3117.0
NOD2 -3115.0
TOMM20 -2897.0
PSMA7 -2759.0
MDM4 -2718.0
UFD1 -2657.0
USP42 -2565.0
PSMF1 -2512.0
CLSPN -2497.0
PRKN -2309.0
VDAC1 -2235.0
VDAC3 -2210.0
MBD6 -2183.0
USP49 -2105.0
SMAD7 -2103.0
ATXN3 -2018.0
SENP8 -1954.0
INO80E -1938.0
CYLD -1843.0
PSMC1 -1839.0
PSMA6 -1800.0
UCHL5 -1741.0
STAM2 -1567.0
RHOA -1526.0
USP20 -1420.0
RUVBL1 -1380.0
USP24 -1359.0
H2AC11 -1249.0
VDAC2 -1153.0
USP12 -1130.0
H2AC8 -1109.0
USP28 -1074.0
CCNA1 -948.0
TGFBR2 -915.0
PSMD1 -818.0
USP14 -772.0
MYC -745.0
UBB -665.0
PSMA4 -648.0
OTUD3 -645.0
USP33 -506.0
KEAP1 -351.0
TRRAP -217.0
RPS27A -126.0
BARD1 -51.0
USP44 -5.0
MDM2 136.0
USP25 140.0
TFPT 245.0
TAB1 262.0
USP7 268.0
USP15 387.0
H2AC16 397.0
RIPK2 437.0
ESR1 559.0
TGFB1 602.0
HGS 680.0
MUL1 831.0
USP4 835.0
H2BC17 842.0
IL33 865.0
USP16 929.0
PSMD11 1023.0
ACTL6A 1091.0
HIF1A 1245.0
NEDD8 1274.0
PSMB4 1285.0
PSMA5 1304.0
KAT2A 1331.0
BABAM2 1393.0
PSMC4 1596.0
FOXK2 1694.0
USP5 1701.0
FOXK1 1817.0
NLRP3 1824.0
AXIN2 1970.0
MYSM1 1990.0
OTUB1 2018.0
PSME2 2084.0
INO80B 2396.0
ARRB2 2582.0
UBE2D1 2677.0
PSMD12 2806.0
AXIN1 3098.0
ACTB 3141.0
CDC20 3609.0
PSMD14 3679.0
UIMC1 3738.0
SMAD2 4200.0
OTUB2 4327.0
PSMB6 4375.0
RNF135 4432.0
CFTR 4482.0
PTRH2 4483.0
JOSD2 4525.0
TADA2B 4665.0
ASXL1 4734.0
USP18 4786.0
CDK1 4923.0
RNF123 4970.0
OTUD7A 5051.0
SMAD1 5151.0
NFKBIA 5179.0
KDM1B 5343.0
OTUD7B 5439.0
SMURF2 5581.0
SEM1 5631.0
TP53 5757.0
USP10 5891.0
TRAF3 5900.0
PSMD4 6169.0
UBA52 6282.0
SNX3 6298.0
TNIP1 6391.0
PSMD5 6795.0
USP8 6959.0
USP2 8213.0
ABRAXAS2 8446.0
ADRB2 8786.0
FKBP8 8994.0
PSMB11 9506.0
UCHL1 9707.0


REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_HSCS

REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_HSCS
1282
set REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_HSCS
setSize 121
pANOVA 3.61e-13
s.dist -0.382
p.adjustANOVA 3.3e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
PSMB7 -10651.0
PSMC6 -10621.0
SPI1 -10569.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
PSMD2 -10209.0
H2AC20 -10208.0
H2BC15 -10189.0
TAL1 -10125.0
PSMC2 -10087.0
H2AC7 -10035.5
H2BC7 -10035.5

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
PSMB7 -10651.0
PSMC6 -10621.0
SPI1 -10569.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
PSMD2 -10209.0
H2AC20 -10208.0
H2BC15 -10189.0
TAL1 -10125.0
PSMC2 -10087.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
PSMA3 -9831.0
GATA3 -9812.0
PSMB8 -9616.0
PSME1 -9420.0
H2BC26 -9346.0
PSMC5 -9310.0
H2BC4 -9285.0
TCF12 -9243.0
MYB -9069.0
PSMA8 -9037.0
H2BC9 -9020.5
H3C7 -9020.5
PSME3 -8645.0
GATA2 -8618.0
H2BC3 -8572.0
PSMD3 -8488.0
H4C3 -8451.0
H2AC6 -8428.0
UBC -8277.0
RUNX1 -8234.0
H2BC10 -8174.0
PSMD6 -8047.0
CBFB -7940.0
MNAT1 -7673.0
H4C11 -7658.0
H2BC13 -7580.0
PSMB10 -7549.0
CCNH -7537.0
H3C1 -7492.0
PSMD7 -7470.0
ITCH -7429.0
PSMB5 -7376.0
H2BC5 -7339.0
PSMB2 -7000.0
PSMB9 -6985.0
PSMD9 -6972.0
LMO2 -6539.0
H2BC1 -6434.0
KMT2A -6224.0
PSMC3 -6093.0
PSMD13 -5903.0
ABL1 -5559.0
H3-3B -5536.0
H2BC8 -5414.0
H3C4 -5404.0
H3-3A -5377.0
CDK7 -5280.0
PSMA2 -5113.0
PSMD8 -5084.0
H2AC4 -4647.0
PSMA1 -4584.0
H3C8 -4535.0
H2BC11 -4063.0
PSMB3 -4011.0
PSME4 -3807.0
H4C13 -3564.0
PSMB1 -3117.0
PSMA7 -2759.0
PSMF1 -2512.0
H4C2 -2432.0
H2AZ2 -1872.0
PSMC1 -1839.0
PSMA6 -1800.0
LDB1 -1228.0
H2AC8 -1109.0
H2AJ -963.0
PSMD1 -818.0
UBB -665.0
PSMA4 -648.0
RPS27A -126.0
H4C12 -107.0
H4C1 323.0
YAP1 465.0
H4C8 685.0
H2BC17 842.0
H2AX 876.0
PSMD11 1023.0
PSMB4 1285.0
PSMA5 1304.0
PSMC4 1596.0
H3C11 1739.0
TCF3 1961.0
PSME2 2084.0
H3C10 2461.0
H4C5 2528.0
PSMD12 2806.0
PSMD14 3679.0
H3C2 3733.0
H4C4 4097.0
PSMB6 4375.0
H2AZ1 4397.0
H4C16 4865.0
H4C6 5430.0
SEM1 5631.0
LMO1 5962.0
PSMD4 6169.0
UBA52 6282.0
PSMD5 6795.0
TP73 7334.0
PSMB11 9506.0


REACTOME_CELLULAR_SENESCENCE

REACTOME_CELLULAR_SENESCENCE
503
set REACTOME_CELLULAR_SENESCENCE
setSize 189
pANOVA 8.16e-13
s.dist -0.302
p.adjustANOVA 7.05e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
MIR24-2 -10766.0
H2AC14 -10727.0
TXN -10530.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
MOV10 -10287.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
RPS6KA1 -10164.0
FZR1 -10150.0
RB1 -10080.0
H2AC7 -10035.5
H2BC7 -10035.5

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
MIR24-2 -10766.0
H2AC14 -10727.0
TXN -10530.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
MOV10 -10287.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
RPS6KA1 -10164.0
FZR1 -10150.0
RB1 -10080.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
CDK6 -9698.0
SP1 -9694.0
CCNE2 -9649.0
MAPK14 -9643.0
MAP2K6 -9611.0
IL6 -9492.0
H2BC26 -9346.0
H2BC4 -9285.0
H1-2 -9191.0
ANAPC16 -9057.0
H2BC9 -9020.5
H3C7 -9020.5
CXCL8 -8858.0
BMI1 -8777.0
CDC23 -8726.0
CDKN2C -8656.0
SUZ12 -8594.0
H2BC3 -8572.0
ETS2 -8482.0
H4C3 -8451.0
H2AC6 -8428.0
MIR24-1 -8349.0
UBC -8277.0
STAT3 -8252.0
H2BC10 -8174.0
TERF1 -8166.0
KAT5 -8114.0
ANAPC7 -8113.0
KDM6B -8060.0
CDK2 -7826.0
TNRC6B -7724.0
MRE11 -7695.0
H4C11 -7658.0
H2BC13 -7580.0
AGO4 -7579.0
H3C1 -7492.0
CDC16 -7384.0
NBN -7344.0
H2BC5 -7339.0
RBBP4 -7271.0
CDC26 -7245.0
MAPKAPK5 -7178.0
TFDP2 -7095.0
H1-5 -6899.0
CBX8 -6705.0
CCNA2 -6534.0
H2BC1 -6434.0
CDKN1B -6381.0
H1-3 -6378.0
MAP3K5 -6350.0
ANAPC5 -6314.0
LMNB1 -6160.0
CEBPB -6129.0
UBE2E1 -6123.0
ACD -5957.5
IFNB1 -5863.0
CDKN2A -5841.0
UBE2S -5833.0
H3-3B -5536.0
CCNE1 -5513.0
H2BC8 -5414.0
H3C4 -5404.0
H3-3A -5377.0
E2F3 -5327.0
TNIK -5126.0
CBX6 -5107.0
TFDP1 -5000.0
RNF2 -4904.0
H2AC4 -4647.0
H3C8 -4535.0
H1-4 -4179.0
MAPKAPK3 -4102.0
H2BC11 -4063.0
CDC27 -4048.0
MAPK7 -3897.0
HMGA2 -3733.0
CBX4 -3688.0
E2F1 -3673.0
ANAPC2 -3595.0
H4C13 -3564.0
ANAPC10 -3558.0
ASF1A -3195.0
ETS1 -3176.0
POT1 -3175.0
MAPK1 -3156.0
ERF -3124.0
MAPK3 -3089.0
AGO3 -3073.0
UBN1 -3061.0
PHC2 -3014.0
JUN -2945.0
EED -2898.0
HIRA -2827.0
MDM4 -2718.0
ATM -2668.0
EZH2 -2496.0
H4C2 -2432.0
MAP4K4 -2334.0
EHMT2 -2233.0
TERF2 -2059.0
H2AZ2 -1872.0
ANAPC11 -1849.0
EP400 -1729.0
CDKN1A -1607.0
HMGA1 -1568.0
MAPK10 -1331.0
MAPKAPK2 -1227.0
H2AC8 -1109.0
TERF2IP -1096.0
H2AJ -963.0
CCNA1 -948.0
E2F2 -920.0
FOS -894.0
CBX2 -849.0
RING1 -740.0
UBB -665.0
NFKB1 -487.0
MAP2K4 -452.0
TNRC6A -436.0
MAPK9 -429.0
SCMH1 -327.0
ANAPC4 -298.0
RPS27A -126.0
H4C12 -107.0
ID1 -106.0
MDM2 136.0
H4C1 323.0
AGO1 376.0
MINK1 600.0
H4C8 685.0
H2BC17 842.0
H2AX 876.0
TINF2 1072.0
CDK4 1550.0
PHC3 1727.0
H3C11 1739.0
CABIN1 2002.0
H3C10 2461.0
H4C5 2528.0
UBE2D1 2677.0
MAP2K3 2764.0
ANAPC1 2923.0
EHMT1 3168.0
TNRC6C 3185.0
MAPK8 3528.0
RPS6KA2 3715.0
H3C2 3733.0
MAP2K7 3747.0
H1-0 3967.0
CDKN2B 4021.0
H4C4 4097.0
H2AZ1 4397.0
MAPK11 4578.0
IGFBP7 4831.0
H4C16 4865.0
RAD50 5232.0
H4C6 5430.0
TP53 5757.0
PHC1 6131.0
ANAPC15 6148.0
UBA52 6282.0
RELA 6961.0
H3-4 7087.0
VENTX 8299.0
UBE2C 8787.0
H1-1 8990.0
CDKN2D 9657.0
IL1A 10020.0


REACTOME_GPCR_LIGAND_BINDING

REACTOME_GPCR_LIGAND_BINDING
834
set REACTOME_GPCR_LIGAND_BINDING
setSize 444
pANOVA 1.06e-12
s.dist 0.197
p.adjustANOVA 8.72e-11



Top enriched genes

Top 20 genes
GeneID Gene Rank
MLN 10633
TAC3 10566
UCN2 10554
WNT8A 10553
GHRHR 10508
LPAR5 10498
CHRM4 10490
CCL22 10472
GNGT2 10448
CCL19 10427
GHRH 10420
CCL13 10381
TAS1R3 10377
MLNR 10345
CCL5 10328
PROKR1 10320
PPY 10304
TAS2R41 10261
GALR3 10243
TAS2R13 10223

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MLN 10633
TAC3 10566
UCN2 10554
WNT8A 10553
GHRHR 10508
LPAR5 10498
CHRM4 10490
CCL22 10472
GNGT2 10448
CCL19 10427
GHRH 10420
CCL13 10381
TAS1R3 10377
MLNR 10345
CCL5 10328
PROKR1 10320
PPY 10304
TAS2R41 10261
GALR3 10243
TAS2R13 10223
CCL27 10220
NPW 10146
HCRTR1 10123
INSL5 10093
PROK1 10059
GNB3 10044
UCN 10040
CCR3 10028
GNG11 10008
WNT9B 9984
CCL17 9933
CCL16 9860
GPR37L1 9855
CXCR2 9804
CCL20 9802
RAMP3 9780
SCT 9710
GPR31 9705
HCAR1 9676
GLP1R 9640
PPBP 9636
UTS2R 9612
HTR4 9590
ADORA1 9584
LPAR1 9544
ADRA1D 9502
TACR2 9481
P2RY6 9474
CX3CL1 9438
GPR55 9434
GPR4 9432
ADORA2A 9421
PRLH 9415
TAS2R60 9409
TAS2R14 9398
RLN3 9370
ACKR2 9333
CHRM1 9309
KEL 9303
RAMP2 9301
CCL11 9274
WNT7A 9272
CXCL9 9241
MCHR1 9232
XCL1 9205
C5AR2 9180
CCR2 9141
POMC 9122
WNT9A 9103
CORT 9076
TAS1R2 9047
SCTR 9021
FFAR4 8900
PTAFR 8896
CCR9 8857
UTS2 8803
ADRB2 8786
GRM4 8768
TAS1R1 8724
CXCR1 8715
FFAR1 8694
GNRH2 8686
TAAR1 8667
FZD4 8661
VIP 8660
CCR6 8634
HTR1D 8622
IAPP 8531
CCRL2 8523
CXCR5 8494
CCL2 8464
CCL1 8429
PTH1R 8423
CX3CR1 8393
QRFP 8344
PTGIR 8327
NPY2R 8307
MC1R 8260
PYY 8254
ADCYAP1R1 8236
CRHR1 8198
NPFFR1 8139
OXER1 8118
ACKR4 8111
WNT2B 8079
GABBR2 8074
CCKAR 8039
NMUR1 7976
CMKLR1 7904
C3AR1 7878
NPY 7862
HRH1 7820
GCG 7768
ADGRE1 7728
AGT 7651
CXCL16 7609
CXCL5 7515
GNGT1 7502
NTSR1 7446
GPR39 7384
RHO 7351
KISS1 7299
ADM2 7293
DRD2 7269
OPN3 7200
CCL7 7186
S1PR3 7183
NPBWR2 7174
GPR132 7143
AGTR1 7090
PLPPR3 7070
RLN2 7058
TAC1 7056
P2RY2 7022
PDYN 6987
AVP 6951
PTH2 6905
GRM2 6824
GPR183 6794
TAS2R39 6742
TACR1 6709
EDNRB 6681
GRM6 6658
RXFP4 6648
XCR1 6621
F2 6618
CRHR2 6613
UTS2B 6611
TRHR 6603
GNG13 6596
PLPPR2 6562
CXCL12 6390
WNT16 6259
DRD4 6240
CCR5 6200
CGA 6197
MC5R 6125
KNG1 6104
LPAR3 6066
SSTR4 6055
SMO 6045
CALCR 5980
C3 5919
ECE2 5899
WNT3A 5870
CASR 5869
GABBR1 5842
CXCL2 5815
GPR68 5731
GPR17 5695
TAAR5 5686
IHH 5594
FSHR 5546
BDKRB1 5480
GPR35 5277
HTR1E 5261
FFAR3 5243
WNT7B 5065
GIPR 4882
GALR2 4839
GALR1 4770
TAS2R5 4699
PNOC 4689
BDKRB2 4679
OPRL1 4656
GNG2 4615
PSAP 4611
MC3R 4559
NPY1R 4439
HTR1F 4430
VIPR1 4374
UCN3 4366
RXFP1 4321
GNG12 4316
GPER1 4314
CCR10 4310
CCK 4301
WNT2 4297
GNB2 4244
CXCL1 4149
KISS1R 4131
CCL28 4119
TAAR9 4047
PTGDR 3939
NPB 3833
WNT10A 3823
F2R 3760
PTH2R 3742
OPRD1 3682
DRD5 3605
P2RY11 3601
NMU 3560
CXCL13 3454
CNR2 3402
PTCH2 3401
WNT6 3388
GNG7 3330
PTCH1 3310
P2RY12 3278
WNT4 3225
GNG8 3100
NPY5R 3097
TAS2R8 3022
LPAR2 2993
TAS2R40 2879
F2RL1 2813
NMB 2741
NPBWR1 2709
GNG5 2685
CCL3 2612
GNB4 2592
WNT11 2584
ADRA1B 2520
ADRB1 2501
NTS 2442
RAMP1 2387
CALCA 2200
RGR 2181
WNT3 2143
GRM7 2098
PF4 2093
CALCRL 1973
GRM8 1911
NTSR2 1837
ACKR1 1835
CHRM2 1826
GRM1 1821
GNRH1 1735
WNT10B 1637
PTGER1 1586
INSL3 1447
GAL 1395
EDN3 1384
PTGER4 1291
VIPR2 1257
FZD3 1239
CCR7 1236
EDN1 1227
ADRA2A 1181
ADRA2B 1141
CHRM3 1114
SSTR1 1013
MC2R 1001
EDNRA 943
CCL21 902
TSHR 707
OPN1SW 689
OXGR1 633
GNG4 613
TAS2R4 478
HCRT 328
SSTR2 327
CCL23 230
OXTR 208
P2RY14 182
C5AR1 -26
FZD5 -48
HCAR2 -62
APLNR -178
PTGFR -308
WNT1 -316
PTHLH -382
HTR6 -421
PLPPR5 -565
OPN5 -578
TBXA2R -618
S1PR1 -631
HRH2 -737
PTH -749
GPR65 -821
HTR2A -829
ECE1 -859
EDN2 -945
GNB1 -959
OPRM1 -1005
FZD9 -1081
NLN -1281
S1PR4 -1318
S1PR5 -1411
HTR2B -1494
TAAR6 -1575
ADRA2C -1621
P2RY13 -1660
CXCR4 -1674
SHH -1986
HTR5A -1989
LTB4R -2130
PMCH -2149
GNRHR -2176
GRM5 -2204
DHH -2251
C5 -2310
CXCR6 -2426
TAS2R46 -2440
RXFP2 -2699
CCKBR -2902
AVPR1A -3043
HRH3 -3056
TAS2R1 -3184
FZD7 -3253
TAS2R19 -3256
CNR1 -3288
GLP2R -3309
NMS -3349
GIP -3350
ADRB3 -3367
ADGRE5 -3443
MTNR1B -3446
CXCL3 -3451
FPR3 -3459
ADGRE2 -3496
ADORA3 -3509
GPR37 -3635
ADGRE3 -3640
GNB5 -3644
TAS2R50 -3737
CHRM5 -3841
TRH -3869
CXCL11 -3898
LHCGR -3915
ADRA1A -4065
QRFPR -4101
GPHB5 -4119
SUCNR1 -4133
PLPPR4 -4143
HEBP1 -4246
PENK -4279
DRD1 -4293
CCR4 -4444
ANXA1 -4452
PLPPR1 -4539
RXFP3 -4651
PROK2 -4868
GHSR -4922
S1PR2 -5023
TAS2R20 -5195
APP -5218
CRH -5220
AVPR1B -5243
NMUR2 -5317
FZD8 -5369
SST -5379
WNT5A -5461
FPR2 -5517
GPBAR1 -5538
DRD3 -5541
NPFFR2 -5562
TAS2R30 -5747
HTR7 -5809
CD55 -5994
NPSR1 -5997
LTB4R2 -6070
OPN4 -6111
FFAR2 -6188
FZD1 -6349
PTGER3 -6420
GPRC6A -6450
CXCL6 -6452
TSHB -6594
TAAR2 -6612
NPFF -6680
FZD6 -6686
HCRTR2 -6780
TAS2R38 -6990
FPR1 -7227
TAS2R42 -7527
PROKR2 -7528
MTNR1A -7596
CCL25 -7600
LPAR6 -7655
MCHR2 -7692
CCR8 -7760
P2RY1 -7798
HTR1A -7875
MC4R -7897
TAS2R9 -7939
FZD2 -8031
ADM -8101
SAA1 -8169
WNT8B -8185
CALCB -8248
SSTR3 -8361
RRH -8495
GNG3 -8510
XCL2 -8522
GNG10 -8561
GPR18 -8731
TAS2R7 -8736
F2RL2 -8795
ADORA2B -8845
CXCL8 -8858
CCR1 -8936
ADCYAP1 -9043
F2RL3 -9428
GRP -9489
SSTR5 -9590
GRM3 -9668
PTGER2 -9686
TAS2R43 -9752
NPS -9769
TAS2R16 -9876
PTGDR2 -9903
GHRL -10066
GPHA2 -10079
NMBR -10107
HTR1B -10130
OPRK1 -10174
FZD10 -10260
TACR3 -10390
PRLHR -10409
TAS2R31 -10471
LHB -10472
GNAS -10554
ACKR3 -10691
CYSLTR2 -10747
TAS2R3 -10750
FSHB -10894
CXCL10 -10962
TAS2R10 -11012
TAAR8 -11090
CRHBP -11111
OXT -11123
HRH4 -11167
CCL4 -11241


REACTOME_DNA_REPLICATION_PRE_INITIATION

REACTOME_DNA_REPLICATION_PRE_INITIATION
1101
set REACTOME_DNA_REPLICATION_PRE_INITIATION
setSize 150
pANOVA 2.44e-12
s.dist -0.331
p.adjustANOVA 1.91e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
PSMB7 -10651.0
PSMC6 -10621.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
PSMD2 -10209.0
H2AC20 -10208.0
H2BC15 -10189.0
FZR1 -10150.0
PSMC2 -10087.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
PSMB7 -10651.0
PSMC6 -10621.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
PSMD2 -10209.0
H2AC20 -10208.0
H2BC15 -10189.0
FZR1 -10150.0
PSMC2 -10087.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
MCM5 -9953.0
PRIM2 -9944.0
PSMA3 -9831.0
ORC4 -9685.0
PSMB8 -9616.0
PSME1 -9420.0
H2BC26 -9346.0
PSMC5 -9310.0
H2BC4 -9285.0
ANAPC16 -9057.0
H2BC9 -9020.5
H3C7 -9020.5
PRIM1 -8994.0
KPNB1 -8945.0
KPNA1 -8859.0
CDC23 -8726.0
PSME3 -8645.0
H2BC3 -8572.0
PSMD3 -8488.0
H4C3 -8451.0
H2AC6 -8428.0
UBC -8277.0
H2BC10 -8174.0
ANAPC7 -8113.0
PSMD6 -8047.0
CDK2 -7826.0
H4C11 -7658.0
H2BC13 -7580.0
PSMB10 -7549.0
H3C1 -7492.0
PSMD7 -7470.0
CDC16 -7384.0
PSMB5 -7376.0
POLE4 -7340.0
H2BC5 -7339.0
CDC26 -7245.0
PSMB2 -7000.0
PSMB9 -6985.0
PSMD9 -6972.0
MCM8 -6756.0
POLA2 -6677.0
H2BC1 -6434.0
ANAPC5 -6314.0
ORC3 -6201.0
UBE2E1 -6123.0
PSMC3 -6093.0
PSMD13 -5903.0
UBE2S -5833.0
H3-3B -5536.0
H2BC8 -5414.0
H3C4 -5404.0
H3-3A -5377.0
PSMA2 -5113.0
PSMD8 -5084.0
H2AC4 -4647.0
ORC2 -4586.0
PSMA1 -4584.0
H3C8 -4535.0
MCM10 -4516.0
H2BC11 -4063.0
CDC27 -4048.0
PSMB3 -4011.0
DBF4 -3726.0
ANAPC2 -3595.0
POLE -3565.0
H4C13 -3564.0
ANAPC10 -3558.0
PSMB1 -3117.0
ORC1 -2801.0
PSMA7 -2759.0
PSMF1 -2512.0
H4C2 -2432.0
CDC6 -2240.0
RPA1 -2002.0
H2AZ2 -1872.0
ANAPC11 -1849.0
PSMC1 -1839.0
PSMA6 -1800.0
H2AC8 -1109.0
H2AJ -963.0
PSMD1 -818.0
MCM6 -758.0
CDT1 -686.0
MCM2 -674.0
UBB -665.0
PSMA4 -648.0
ORC6 -370.0
ANAPC4 -298.0
RPS27A -126.0
H4C12 -107.0
POLE3 87.0
H4C1 323.0
POLE2 373.0
MCM3 586.0
H4C8 685.0
H2BC17 842.0
H2AX 876.0
GMNN 1002.0
PSMD11 1023.0
RPA3 1184.0
PSMB4 1285.0
PSMA5 1304.0
PSMC4 1596.0
H3C11 1739.0
KPNA6 1747.0
PSME2 2084.0
RPA2 2309.0
CDC45 2313.0
MCM7 2427.0
H3C10 2461.0
H4C5 2528.0
MCM4 2571.0
UBE2D1 2677.0
PSMD12 2806.0
ANAPC1 2923.0
PSMD14 3679.0
H3C2 3733.0
H4C4 4097.0
PSMB6 4375.0
H2AZ1 4397.0
CDC7 4757.0
H4C16 4865.0
ORC5 5159.0
H4C6 5430.0
SEM1 5631.0
ANAPC15 6148.0
PSMD4 6169.0
UBA52 6282.0
PSMD5 6795.0
UBE2C 8787.0


REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA

REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA
1146
set REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA
setSize 263
pANOVA 2.97e-12
s.dist -0.25
p.adjustANOVA 2.18e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
SNRPN -11091
PRPF6 -10912
GLE1 -10854
FAM32A -10709
PRCC -10612
CPSF2 -10273
ZMAT5 -10078
RBM8A -10008
THOC7 -9867
SLU7 -9843
MAGOHB -9842
MAGOH -9827
U2AF1L4 -9732
HNRNPU -9717
PCBP1 -9650
PRKRIP1 -9544
HNRNPA3 -9498
LSM7 -9451
NUP37 -9289
LSM3 -9276

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SNRPN -11091
PRPF6 -10912
GLE1 -10854
FAM32A -10709
PRCC -10612
CPSF2 -10273
ZMAT5 -10078
RBM8A -10008
THOC7 -9867
SLU7 -9843
MAGOHB -9842
MAGOH -9827
U2AF1L4 -9732
HNRNPU -9717
PCBP1 -9650
PRKRIP1 -9544
HNRNPA3 -9498
LSM7 -9451
NUP37 -9289
LSM3 -9276
POLDIP3 -9265
SRSF8 -9253
RNPC3 -9198
U2SURP -9195
GPATCH1 -9141
PRPF19 -9140
PPIH -9013
NUP50 -8870
ACIN1 -8816
SRSF11 -8791
PLRG1 -8783
POM121 -8700
HNRNPA1 -8664
SRSF10 -8621
AQR -8601
CTNNBL1 -8580
WBP11 -8531
DHX35 -8474
SNRNP200 -8455
NUP42 -8381
WBP4 -8359
CWC27 -8217
NCBP1 -8209
SEH1L -8137
NUP98 -8136
SRRM1 -8132
PPP1R8 -8131
SAP18 -8083
SNU13 -8074
LSM5 -7999
NUP107 -7996
CDC40 -7930
CPSF6 -7910
DDX23 -7726
SNRPB -7665
PRPF4 -7649
LSM4 -7499
SF3B3 -7426
SNRPB2 -7268
DNAJC8 -7255
BUD31 -7222
YJU2 -7193
HNRNPK -7107
PRPF3 -7055
LENG1 -7009
SART1 -6980
NUP214 -6894
CACTIN -6893
POLR2H -6881
NXT1 -6818
SRSF6 -6815
RBM22 -6693
DHX15 -6668
RBM7 -6601
DHX38 -6598
SNRNP40 -6509
NUP160 -6475
SEC13 -6469
CASC3 -6442
RAE1 -6238
SNRNP27 -6143
CSTF1 -6141
HNRNPA2B1 -6137
EFTUD2 -6109
POLR2L -5972
BCAS2 -5923
DDX42 -5805
HSPA8 -5803
NUP155 -5740
SUGP1 -5652
CWC15 -5642
POLR2K -5634
SRSF1 -5591
HNRNPH1 -5540
NUP88 -5526
SRSF5 -5500
SRSF9 -5477
CPSF7 -5460
PCF11 -5367
THOC1 -5330
SNRNP70 -5300
SF3A2 -5259
PRPF38A -5148
CWF19L2 -5080
UBL5 -5053
WTAP -5007
ZC3H11A -4971
MFAP1 -4901
LSM6 -4786
THOC5 -4659
TRA2B -4639
SRRM2 -4633
SNRPA -4631
CPSF1 -4480
PPIL3 -4467
CWC25 -4443
NUP58 -4439
RBM25 -4431
CLP1 -4376
SNRPA1 -4363
HNRNPD -4277
TCERG1 -4147
SDE2 -4118
SNRPD3 -4100
CDC5L -4089
POLR2G -3937
NUP188 -3926
HNRNPM -3894
PCBP2 -3820
POLR2B -3768
ZCRB1 -3735
MTREX -3624
RBM39 -3444
DHX8 -3434
SYF2 -3389
HNRNPL -3278
SF3B1 -3274
HNRNPR -3271
DHX16 -3257
SRSF3 -3037
PAPOLA -2927
SLBP -2909
ZNF830 -2810
DDX46 -2803
SNRPD2 -2767
GTF2F2 -2764
PPWD1 -2653
SF3B6 -2621
WDR70 -2575
PABPN1 -2472
NCBP2 -2442
DDX41 -2322
SYMPK -2275
SNRNP35 -2217
SRSF2 -2063
BUD13 -1934
CCAR1 -1820
POLR2I -1736
U2AF2 -1675
RBM17 -1617
PPIG -1581
LSM2 -1573
CHERP -1569
AAAS -1523
SF1 -1455
SNRPE -1363
TPR -1291
POLR2A -1290
PTBP1 -1245
THOC6 -1219
RANBP2 -1170
SF3A3 -1166
RBM42 -1060
LUC7L3 -1040
SRSF7 -970
NUP153 -930
HNRNPC -921
NUP93 -887
SARNP -780
METTL3 -684
CWC22 -672
NDC1 -624
PHF5A -537
CCDC12 -467
XAB2 -464
SRSF4 -453
PNN -311
SNIP1 -152
SNRPD1 -139
PDCD7 -93
TXNL4A -12
SNW1 45
LSM8 105
NSRP1 165
POLR2C 198
YBX1 363
FYTTD1 374
ALYREF 481
POLR2E 503
DDX39B 742
FUS 916
GTF2F1 936
PRPF8 962
SNRPG 982
C9orf78 1075
SRRT 1110
CPSF4 1150
NUP43 1180
NXF1 1263
SF3B4 1361
HNRNPF 1389
IK 1451
PRPF40A 1662
CSTF3 1711
PRPF31 2074
SF3A1 2123
DHX9 2178
CSTF2T 2262
NUDT21 2268
CPSF3 2301
POLR2D 2370
NUP85 2430
ZMAT2 2436
EIF4A3 2759
NUP205 2803
GCFC2 3011
NUP133 3158
POLR2F 3184
FIP1L1 3206
NUP54 3235
NUP210 3259
PPIL2 3436
EIF4E 3533
DDX39A 3574
SNRPC 3646
POLR2J 3674
DDX5 3974
CHTOP 3988
RNPS1 4053
PPIL4 4125
CRNKL1 4175
PUF60 4461
SF3B2 4465
WDR33 4577
RBM5 4683
NUP35 4792
SNRPF 4945
THOC3 5094
PPIE 5253
SNRNP48 5274
SNRNP25 5356
NUP62 5471
SMNDC1 5774
PRPF18 5788
TFIP11 5846
USP39 5857
METTL14 6243
ISY1 6542
SF3B5 6672
PPIL1 7207
SRSF12 8178
POM121C 8315
SMU1 8799


REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION
1024
set REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION
setSize 1356
pANOVA 3.06e-12
s.dist -0.113
p.adjustANOVA 2.18e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
FCGR3B -11244
APOL1 -11205
EEF2KMT -11124
H2BC14 -11029
NICN1 -10996
PNPLA2 -10985
CALR -10983
METTL22 -10973
DPH5 -10895
MUC15 -10793
PDIA3 -10787
DNAJC3 -10775
RAD23A -10762
H2AC14 -10727
DPM2 -10697
H2AC12 -10676
TGFBR1 -10661
PSMB7 -10651
PSMC6 -10621
TRAPPC3 -10617

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FCGR3B -11244.0
APOL1 -11205.0
EEF2KMT -11124.0
H2BC14 -11029.0
NICN1 -10996.0
PNPLA2 -10985.0
CALR -10983.0
METTL22 -10973.0
DPH5 -10895.0
MUC15 -10793.0
PDIA3 -10787.0
DNAJC3 -10775.0
RAD23A -10762.0
H2AC14 -10727.0
DPM2 -10697.0
H2AC12 -10676.0
TGFBR1 -10661.0
PSMB7 -10651.0
PSMC6 -10621.0
TRAPPC3 -10617.0
RAB34 -10615.0
COMMD3 -10520.0
CNTN3 -10510.0
PIGU -10507.0
EIF5A2 -10476.0
LHB -10472.0
B3GNT8 -10462.0
UBE2M -10407.0
VCPIP1 -10387.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
PIGM -10288.0
GMPPA -10248.0
H2BC12 -10245.0
COPS7B -10227.0
NEU3 -10213.0
PIGX -10211.0
PSMD2 -10209.0
H2AC20 -10208.0
BRCA1 -10206.0
H2BC15 -10189.0
CAND1 -10138.0
PIGY -10126.0
SERPIND1 -10099.0
LMAN1 -10092.0
PSMC2 -10087.0
SOCS2 -10083.0
COMMD6 -10075.0
STX5 -10073.0
RPN2 -10062.0
HLA-A -10047.0
H2AC7 -10035.5
H2BC7 -10035.5
SVBP -10032.0
H2BC21 -10020.0
NOD1 -10009.0
UCHL3 -9976.0
KLHL42 -9972.0
TRIM13 -9964.0
RAB13 -9958.0
COMMD4 -9896.0
TMEM129 -9859.0
ELOB -9858.0
BECN1 -9853.0
RAB4B -9833.0
PSMA3 -9831.0
SOCS3 -9829.0
GATA3 -9812.0
MPI -9798.0
ST3GAL4 -9789.0
TUBA1A -9776.0
RAD21 -9775.0
TUBA3E -9762.0
WDR48 -9688.0
CD59 -9687.0
LRRC41 -9678.0
FBXL12 -9676.0
TUSC3 -9674.0
DCUN1D3 -9665.0
EP300 -9652.0
PIAS1 -9633.0
KLHL9 -9621.0
PSMB8 -9616.0
FBXL15 -9606.0
RTF1 -9598.0
PMM1 -9582.0
YY1 -9573.0
COPZ1 -9550.0
AMTN -9537.0
SEC22A -9521.0
MCRS1 -9509.0
H2AC15 -9502.0
ZNF350 -9496.0
IL6 -9492.0
KBTBD7 -9482.0
MIA2 -9476.0
UBE2J2 -9472.0
DCTN4 -9461.0
ATXN7 -9430.0
PSME1 -9420.0
NEURL2 -9407.0
SIAH2 -9404.0
PIGB -9389.0
B4GALT1 -9381.0
COPB2 -9354.0
H2BC26 -9346.0
KDELR2 -9344.0
CAPZA3 -9318.0
PSMC5 -9310.0
NUP37 -9289.0
H2BC4 -9285.0
COPS3 -9283.0
UBE2W -9278.0
GALNT1 -9257.0
RAB11B -9177.0
CNIH1 -9096.0
CBX5 -9089.0
ASB8 -9083.0
SOCS6 -9076.0
CSNK1D -9073.0
MOGS -9044.0
PSMA8 -9037.0
ANKRD28 -9030.0
H2BC9 -9020.5
EDEM3 -9008.0
PIGV -9000.0
DCAF6 -8980.0
NAPA -8973.0
DYNLL1 -8928.0
UBE2T -8923.0
UBE2H -8903.0
NEGR1 -8896.0
TUBA3C -8877.0
NUP50 -8870.0
PARK7 -8864.0
H2AC13 -8863.0
RAB2A -8861.0
STX17 -8854.0
TOP1 -8832.0
UGGT1 -8826.0
TOMM70 -8822.0
BMI1 -8777.0
EEF1AKMT2 -8770.0
POM121 -8700.0
TNFAIP3 -8695.0
RAB1B -8678.0
DPM1 -8670.0
SIN3A -8665.0
AMFR -8649.0
PSME3 -8645.0
PIGF -8626.0
RAB26 -8614.0
RNF103 -8599.0
PUM2 -8597.0
SUZ12 -8594.0
NCOA2 -8586.0
AMDHD2 -8577.0
COG3 -8573.0
H2BC3 -8572.0
DNAJC24 -8552.0
DCAF16 -8535.0
TMED10 -8521.0
ADAMTS3 -8506.0
TOP2B -8503.0
FBXO9 -8499.0
EIF5A -8494.0
PSMD3 -8488.0
ARFGAP2 -8487.0
H4C3 -8451.0
RCE1 -8445.0
GOSR1 -8441.0
PIGK -8429.0
H2AC6 -8428.0
DCTN2 -8416.0
FN3KRP -8405.0
ARF4 -8394.0
PIAS3 -8391.0
NUCB1 -8389.0
NUP42 -8381.0
RNF146 -8379.0
ARSJ -8363.0
NR4A2 -8347.0
GOLGB1 -8311.0
DCAF8 -8304.0
PCNA -8301.0
RAB27B -8289.0
GOLGA2 -8279.0
UBC -8277.0
PROS1 -8260.0
UBE2V2 -8249.0
PAF1 -8221.0
COPS5 -8199.0
H2BC10 -8174.0
VCPKMT -8162.0
NSMCE1 -8155.0
ACTR5 -8146.0
TRAPPC1 -8143.0
SEH1L -8137.0
NUP98 -8136.0
MAT2B -8135.0
PLAUR -8126.0
ASB17 -8123.0
STAMBP -8122.0
PMM2 -8103.0
SMAD3 -8098.0
MGAT4A -8097.0
USP19 -8077.0
ACTR1A -8070.0
USP13 -8054.0
PSMD6 -8047.0
USP47 -8019.0
CCP110 -8007.0
CTSZ -8001.0
FBXL4 -7998.0
NUP107 -7996.0
UAP1 -7977.0
DPH2 -7967.0
USP21 -7965.0
IFIH1 -7904.0
SEC31A -7903.0
DPP3 -7871.0
TTLL5 -7868.0
WDR20 -7859.0
TAF10 -7853.0
APC -7836.0
CUL4A -7832.0
RAB1A -7794.0
NPM1 -7766.0
UBXN7 -7752.0
RHOT1 -7738.0
ALG9 -7732.0
THSD7B -7708.0
EEF1A1 -7671.0
ST8SIA6 -7669.0
ASXL2 -7663.0
INO80 -7662.0
H4C11 -7658.0
BIRC3 -7652.0
COG2 -7643.0
MDGA2 -7624.0
UBE2D3 -7616.0
MBD5 -7614.0
CDCA8 -7604.0
B3GNT2 -7603.0
H2BC13 -7580.0
COPG1 -7575.0
TRAF2 -7574.0
PSMB10 -7549.0
GPLD1 -7532.0
MIA3 -7483.0
PSMD7 -7470.0
JOSD1 -7449.0
HSP90B1 -7448.0
LYPD5 -7438.0
SMAD4 -7434.0
COPS4 -7428.0
STAM -7421.0
H2AC21 -7400.0
COPS7A -7396.0
PSMB5 -7376.0
HERC2 -7359.0
INO80D -7350.0
H2BC5 -7339.0
STT3A -7335.0
GALNT3 -7334.0
KAT2B -7302.0
DPAGT1 -7272.0
FBXO32 -7261.0
FBXL18 -7252.0
ALG6 -7230.0
MGAT4C -7226.0
SUMO1 -7196.0
DPH7 -7187.0
TUBA1B -7184.0
BLM -7176.0
TMED2 -7173.0
ST3GAL2 -7167.0
ASB2 -7163.0
COG6 -7152.0
SHISA5 -7150.0
CAPZA1 -7141.0
ANK2 -7119.0
RNF168 -7116.0
ING2 -7113.0
HNRNPK -7107.0
CDH2 -7094.0
RIPK1 -7072.0
UMOD -7070.0
ASB7 -7063.0
BET1L -7051.0
MUC7 -7045.0
ACTR10 -7043.0
DYNC1LI1 -7041.0
ARF3 -7032.0
TADA3 -7021.0
MAP3K7 -7012.0
IGFBP3 -7002.0
PSMB2 -7000.0
THRA -6996.0
PSMB9 -6985.0
PSMD9 -6972.0
TFAP2C -6954.0
ALG11 -6947.0
DCAF5 -6941.0
ST8SIA3 -6906.0
L3MBTL2 -6904.0
NUP214 -6894.0
VCP -6884.0
ST3GAL1 -6873.0
SERPINA1 -6848.0
TGOLN2 -6830.0
LSAMP -6823.0
MANEA -6820.0
RNF20 -6809.0
CNTN4 -6799.0
FBXW5 -6798.0
CDC25A -6793.0
PGAP1 -6790.0
GPAA1 -6783.0
MITF -6727.0
NAPB -6722.0
PIGS -6714.0
BABAM1 -6706.0
CBX8 -6705.0
OPCML -6700.0
SKP1 -6672.0
ASB6 -6656.0
CAPZA2 -6624.0
NR3C1 -6622.0
SRD5A3 -6620.0
COPE -6616.0
NSMCE3 -6590.0
MAN1A1 -6583.0
DNMT1 -6562.0
DOLK -6559.0
DNMT3B -6553.0
CCNA2 -6534.0
CNTN5 -6521.0
PCGF2 -6508.0
TUBA1C -6503.0
RAB11A -6502.0
NUP160 -6475.0
DPH6 -6474.0
SEC13 -6469.0
GALNT5 -6465.0
MRTFA -6462.0
BIRC2 -6460.0
H2BC1 -6434.0
TRAPPC6B -6422.0
BTBD1 -6404.0
CTSA -6401.0
POMGNT1 -6376.0
NR3C2 -6368.0
H2AC25 -6343.0
NPLOC4 -6329.0
ADAMTS18 -6325.0
DDX17 -6307.0
ALB -6293.0
SEC22B -6283.0
ART3 -6277.0
FBXL3 -6272.0
MCFD2 -6261.0
RAE1 -6238.0
UBA6 -6215.0
DYNC1LI2 -6196.0
CHGB -6184.0
ADAMTS6 -6167.0
CAPZB -6166.0
OS9 -6150.0
RNF7 -6133.0
UBE2E1 -6123.0
STAMBPL1 -6115.0
PIAS4 -6095.0
PSMC3 -6093.0
NCOR2 -6078.0
PIGQ -6046.0
ALG8 -6042.0
GORASP1 -6022.0
TRIM4 -6020.0
FGA -6019.0
CUL3 -6004.0
CD55 -5994.0
RAB8B -5981.0
TUBAL3 -5968.0
SKP2 -5945.0
VGF -5941.0
HDAC1 -5913.0
PSMD13 -5903.0
ABRAXAS1 -5893.0
THSD7A -5872.0
NRN1L -5855.0
RAB39A -5843.0
GALNT11 -5842.0
CDKN2A -5841.0
UBE2S -5833.0
FUT8 -5825.0
HSPA8 -5803.0
B3GLCT -5787.0
RAB6A -5776.0
LMAN2L -5753.0
NUP155 -5740.0
PIGH -5734.0
IGFBP4 -5722.0
RAB10 -5719.0
USP30 -5713.0
GNE -5712.0
ADAMTS15 -5710.0
SPSB2 -5695.0
DDB2 -5674.0
CUL7 -5671.0
RAB22A -5660.0
ADAMTS10 -5654.0
ALG14 -5641.0
COP1 -5635.0
B4GALT4 -5613.0
SLC35A1 -5608.0
ACTR8 -5606.0
KTN1 -5587.0
METTL21A -5568.0
COG5 -5567.0
SQSTM1 -5563.0
RAD52 -5549.0
ARF1 -5546.0
NUP88 -5526.0
MUC1 -5524.0
SPP2 -5523.0
PML -5486.0
SMC5 -5472.0
SUMF2 -5459.0
FUT3 -5423.0
H2BC8 -5414.0
USP22 -5401.0
IDE -5400.0
RAB36 -5382.0
MFGE8 -5357.0
RANGAP1 -5347.0
NR2C1 -5305.0
CCNF -5250.0
RNF139 -5242.0
INO80C -5235.0
FN1 -5229.0
APP -5218.0
MAN2A1 -5197.0
TTLL3 -5192.0
RIGI -5177.0
RAB3A -5176.0
GFPT1 -5169.0
UBE2L3 -5168.0
ANK3 -5138.0
PSMA2 -5113.0
DCUN1D4 -5108.0
USP37 -5085.0
PSMD8 -5084.0
SAR1B -5057.0
BAP1 -5052.0
UBA3 -5039.0
TPST1 -5028.0
USP48 -5013.0
DYNC1H1 -5010.0
TNKS -4997.0
SERPINA10 -4991.0
TNIP3 -4983.0
RAD18 -4976.0
DCTN6 -4973.0
ARCN1 -4929.0
ARRB1 -4907.0
SEC24D -4905.0
RNF2 -4904.0
FBXL20 -4885.0
PIAS2 -4881.0
TNIP2 -4865.0
RAB18 -4864.0
VCAN -4863.0
FBXW7 -4860.0
GOSR2 -4852.0
LRR1 -4842.0
AURKA -4806.0
TNKS2 -4789.0
TDG -4767.0
DYNC1I2 -4740.0
BMP4 -4736.0
CDC34 -4726.0
UBE2R2 -4723.0
RAB24 -4716.0
UBE2K -4705.0
ZRANB1 -4669.0
H2AC4 -4647.0
B4GALT5 -4646.0
NFE2L2 -4638.0
DOHH -4607.0
PSMA1 -4584.0
PTEN -4562.0
FBXL7 -4532.0
PRMT3 -4524.0
CNIH2 -4517.0
RNF181 -4515.0
YOD1 -4496.0
MGAT2 -4483.5
DCAF11 -4476.0
EDEM2 -4468.0
NOP58 -4464.0
PIGW -4450.0
RAB3D -4448.0
NUP58 -4439.0
SUDS3 -4430.0
PARP1 -4415.0
HDAC2 -4377.0
SPTAN1 -4334.0
MGAT1 -4280.0
PENK -4279.0
SATB2 -4242.0
COPG2 -4240.0
KLHL5 -4235.0
WRN -4227.0
TRIM25 -4186.0
PPP6R1 -4178.0
SEC24A -4150.0
KLHL2 -4141.0
STAG1 -4121.0
FEM1C -4108.0
GALNT7 -4077.0
CP -4074.0
H2BC11 -4063.0
WDR5 -4056.0
RBX1 -4039.0
ALG2 -4031.0
INCENP -4030.0
ADRM1 -4028.0
DTL -4012.0
PSMB3 -4011.0
ALG10 -4010.0
TRAF6 -3985.0
DAG1 -3984.0
H2AC1 -3983.0
RABGGTB -3971.0
PRSS23 -3950.0
COG8 -3933.0
NUP188 -3926.0
SENP2 -3911.0
MAVS -3892.0
GRIA1 -3885.0
GALNTL6 -3882.0
DDA1 -3861.0
PSME4 -3807.0
XPC -3728.0
FBXO30 -3719.0
CBX4 -3688.0
SCG3 -3659.0
TP53BP1 -3633.0
DCAF13 -3631.0
NFRKB -3616.0
PPP6C -3610.0
AMBN -3607.0
FEM1B -3606.0
ST6GALNAC5 -3568.0
H4C13 -3564.0
COG4 -3559.0
NCOA1 -3556.0
SUMO2 -3536.0
POLB -3527.0
DCUN1D5 -3525.0
RORA -3515.0
CHST10 -3507.0
ARFGAP3 -3501.0
PALB2 -3500.0
TPST2 -3482.0
PIGP -3468.0
GALNT13 -3462.0
CHD3 -3438.0
PPARGC1A -3425.0
AGTPBP1 -3420.0
FBXW2 -3410.0
B3GNT4 -3395.0
UBE2E3 -3390.0
SEC16A -3387.0
DCTN1 -3378.0
FUCA2 -3376.0
TRAPPC6A -3360.0
SEC22C -3342.0
SATB1 -3336.0
NRN1 -3329.0
USP3 -3327.0
NUS1 -3303.0
RAB23 -3296.0
RAB35 -3291.0
KBTBD6 -3287.0
POMK -3284.0
ASB15 -3270.0
SP3 -3262.0
COPB1 -3261.0
USP34 -3242.0
RAD23B -3238.0
H2AC17 -3211.0
FOLR2 -3196.0
COPS2 -3151.0
KLHL25 -3149.0
PSMB1 -3117.0
NOD2 -3115.0
ANO8 -3081.0
GBF1 -3075.0
SCFD1 -3070.0
RAB40C -3041.0
RAB3C -3029.0
CALU -3025.0
PHC2 -3014.0
USO1 -3012.0
DCUN1D2 -2997.0
MBTPS1 -2990.0
CUL1 -2987.0
TFG -2984.0
GCNT7 -2973.0
ADAMTSL3 -2956.0
SLC17A5 -2917.0
ADAMTS19 -2910.0
TRAPPC10 -2903.0
TOMM20 -2897.0
NRIP1 -2871.0
PGM3 -2863.0
AREG -2842.0
SAFB -2821.0
PIGN -2776.0
ADAMTS1 -2774.0
PSMA7 -2759.0
TTLL4 -2727.0
LY6H -2726.0
GANAB -2722.0
MDM4 -2718.0
MVD -2688.0
UFD1 -2657.0
PDIA6 -2652.0
THBS1 -2605.0
SEC24C -2586.0
USP42 -2565.0
POMT1 -2563.0
PEX2 -2559.0
YKT6 -2558.0
APOA1 -2522.0
PSMF1 -2512.0
CLSPN -2497.0
DERL2 -2494.0
MLEC -2491.0
ARSB -2489.0
H4C2 -2432.0
ADAMTS16 -2417.0
NTNG1 -2396.0
UBE2B -2392.0
BCL10 -2385.0
KLHL20 -2370.0
ST6GAL2 -2357.0
FUCA1 -2348.0
PRKN -2309.0
LTBP1 -2294.0
OTULIN -2278.0
HDAC7 -2273.0
SERPINC1 -2249.0
RAB5B -2247.0
ASB3 -2246.0
VDAC1 -2235.0
SPP1 -2232.0
B4GALT3 -2222.0
PRKCSH -2214.0
VDAC3 -2210.0
MBD6 -2183.0
LEO1 -2164.0
FSTL3 -2153.0
ADAMTSL1 -2146.0
NR1H3 -2138.0
RAB37 -2131.0
ELOC -2118.0
USP49 -2105.0
SMAD7 -2103.0
RBBP5 -2037.0
VASH2 -2034.0
ST3GAL6 -2028.0
MPDU1 -2025.0
ATXN3 -2018.0
THBS2 -2004.0
RPA1 -2002.0
GCNT4 -1985.0
SENP8 -1954.0
INO80E -1938.0
COMMD8 -1910.0
KBTBD8 -1858.0
CYLD -1843.0
KLHL3 -1841.0
PSMC1 -1839.0
PIGC -1825.0
COMMD2 -1823.0
FBXW8 -1815.0
CHST8 -1812.0
POMGNT2 -1806.0
PSMA6 -1800.0
TRIM27 -1778.0
AGBL5 -1771.0
DCTN3 -1770.0
GALNT17 -1753.0
RARA -1743.0
UCHL5 -1741.0
FBXO31 -1740.0
NGLY1 -1735.0
FBXW11 -1723.0
COMMD9 -1644.0
TOPORS -1622.0
RAB2B -1611.0
CDKN1A -1607.0
CREBBP -1603.0
SPON1 -1582.0
STAM2 -1567.0
COPA -1564.0
RHOA -1526.0
AAAS -1523.0
DHDDS -1516.0
SP100 -1513.0
F5 -1493.0
ADAMTS12 -1467.0
SENP5 -1451.0
CUL2 -1439.0
USP20 -1420.0
FBXO7 -1419.0
TFAP2A -1408.0
MAN2A2 -1397.0
POFUT2 -1395.0
RUVBL1 -1380.0
USP24 -1359.0
PEX13 -1358.0
VHL -1347.0
FBXO22 -1341.0
LMO7 -1337.0
SAE1 -1335.0
RAB21 -1309.0
SUMO3 -1301.0
TPR -1291.0
H2AC11 -1249.0
SPTBN1 -1242.0
ERCC8 -1178.0
RANBP2 -1170.0
SOCS5 -1168.0
VDAC2 -1153.0
FCSK -1146.0
TUBB4B -1137.0
SENP1 -1133.0
USP12 -1130.0
H2AC8 -1109.0
USP28 -1074.0
ADAMTS5 -1042.0
MGAT4B -1034.0
ST8SIA4 -1023.0
DHPS -1011.0
RAB7A -993.0
UBE2Z -976.0
CCNA1 -948.0
GALNT2 -947.0
NUP153 -930.0
HNRNPC -921.0
TGFBR2 -915.0
RAB33B -913.0
ALG5 -910.0
ITIH2 -903.0
NUP93 -887.0
FURIN -867.0
ARSK -863.0
CBX2 -849.0
CTR9 -832.0
PEX12 -820.0
PSMD1 -818.0
CKAP4 -784.0
USP14 -772.0
MYC -745.0
RING1 -740.0
ASB13 -736.0
BTRC -717.0
CALM1 -694.0
CSF1 -676.0
UBB -665.0
NPL -657.0
EEF2 -651.0
PSMA4 -648.0
OTUD3 -645.0
NDC1 -624.0
FPGT -608.0
TTL -595.0
TPGS1 -586.0
NSMCE2 -554.0
PRKDC -539.0
MUCL1 -523.0
USP33 -506.0
ASB1 -488.0
BPIFB2 -448.0
FBXO4 -427.0
RAB30 -413.0
NAGK -389.0
FBXL13 -377.0
SYVN1 -374.0
KEAP1 -351.0
SCMH1 -327.0
SEMA5A -322.0
PGR -310.0
C1GALT1 -255.0
CISH -240.0
DYNC1I1 -230.0
ULBP2 -229.0
SMC6 -222.0
TRRAP -217.0
NR1H2 -214.0
TRAPPC2L -184.0
SLC35C1 -175.0
BET1 -174.0
NAE1 -165.0
RAB5A -138.0
DCAF7 -128.0
RPS27A -126.0
SCG2 -120.0
NUB1 -111.0
H4C12 -107.0
ADAMTS20 -99.0
ALG12 -63.0
RNF144A -56.0
BARD1 -51.0
ST8SIA1 -25.0
KLHL11 -15.0
USP44 -5.0
CAMKMT -4.0
ALG10B 39.0
UBE2G2 43.0
AURKB 55.0
AGBL1 69.0
MUC17 71.0
TOP2A 81.0
GMPPB 89.0
RAB32 103.0
MDM2 136.0
USP25 140.0
MUC16 149.0
GAN 195.0
CTBP1 197.0
GALNT4 203.0
PLET1 229.0
CPM 231.0
MAN1A2 235.0
TFPT 245.0
MELTF 257.0
TAB1 262.0
USP7 268.0
NFKB2 284.0
SEL1L 285.0
TUBB2A 305.0
H4C1 323.0
B3GNT3 338.0
NSMCE4A 346.0
COG1 383.0
USP15 387.0
H2AC16 397.0
MARCHF6 416.0
RAB29 427.0
KCTD6 430.0
RIPK2 437.0
BST1 441.0
RABGGTA 458.0
APOA2 460.0
WAC 501.0
MBD1 538.0
ESR1 559.0
UBE2I 578.0
ZNF131 595.0
TGFB1 602.0
CANX 654.0
FBXL19 657.0
RPN1 664.0
HGS 680.0
H4C8 685.0
KLHL21 714.0
RXRA 721.0
UBA2 740.0
NEU1 768.0
GALNT12 774.0
ENGASE 783.0
CUL5 797.0
TPGS2 799.0
PROZ 803.0
SEC23A 830.0
MUL1 831.0
USP4 835.0
H2BC17 842.0
PPARG 855.0
IL33 865.0
TMEM115 900.0
FBXO6 912.0
USP16 929.0
POMT2 954.0
DCAF10 956.0
ICMT 969.0
ADAMTS17 1019.0
PSMD11 1023.0
ARSA 1028.0
TMED9 1049.0
UBE2D2 1066.0
MUC13 1082.0
ACTL6A 1091.0
GALNT9 1113.0
EDEM1 1131.0
NUP43 1180.0
PEX5 1200.0
HIF1A 1245.0
NEDD8 1274.0
UBE2N 1276.0
PSMB4 1285.0
CDC73 1290.0
PSMA5 1304.0
TGFA 1315.0
B3GALNT2 1327.0
KAT2A 1331.0
DPH3 1341.0
MGAT5 1386.0
BABAM2 1393.0
DMP1 1442.0
P4HB 1473.0
LAMC1 1493.0
SUMF1 1522.0
RFT1 1527.0
DAXX 1573.0
DCAF17 1575.0
PSMC4 1596.0
HIPK2 1642.0
PPP6R3 1643.0
NANP 1658.0
FOXK2 1694.0
USP5 1701.0
PHC3 1727.0
SMC3 1750.0
TMED7 1760.0
PPARA 1763.0
UBE2F 1782.0
LMAN2 1785.0
WSB1 1794.0
DPH1 1807.0
IZUMO1R 1811.0
FOXK1 1817.0
NLRP3 1824.0
ALG1 1863.0
B4GALNT2 1887.0
DPM3 1893.0
ARF5 1905.0
RNF152 1922.0
AXIN2 1970.0
FBXW9 1971.0
MYSM1 1990.0
NSF 1993.0
OTUB1 2018.0
SKIC8 2035.0
LYPD1 2047.0
PSME2 2084.0
COG7 2122.0
RAB43 2158.0
NR1H4 2175.0
WSB2 2187.0
UHRF2 2189.0
FBXL8 2208.0
SPTA1 2214.0
TFAP2B 2263.0
RAB20 2280.0
BIRC5 2299.0
FBXL22 2308.0
FBXL5 2316.0
UGGT2 2318.0
COMMD1 2348.0
HLTF 2356.0
RAET1G 2367.0
INO80B 2396.0
SEC24B 2402.0
TRAPPC4 2403.0
NUP85 2430.0
ADAMTS9 2464.0
WDTC1 2469.0
RCN1 2480.0
TTLL2 2488.0
ARFGAP1 2492.0
H4C5 2528.0
GFUS 2568.0
ARRB2 2582.0
MAN1C1 2599.0
ETFB 2609.0
COPS8 2631.0
COMMD10 2635.0
TNC 2642.0
DAD1 2645.0
RNF185 2647.0
GALNT8 2648.0
UBE2D1 2677.0
TUBA3D 2717.0
RAB14 2732.0
TBC1D20 2735.0
TMED3 2742.0
CMAS 2774.0
NUP205 2803.0
PSMD12 2806.0
LRRC49 2889.0
RAB38 2941.0
GMDS 2972.0
NTM 2976.0
GALNT10 2979.0
KLHL41 2987.0
MDC1 2996.0
RAB44 3009.0
MUC3A 3025.0
HDAC4 3070.0
DCUN1D1 3082.0
AXIN1 3098.0
FBXO11 3117.0
ACTB 3141.0
COPS6 3142.0
MSLN 3143.0
FBXO21 3145.0
NUP133 3158.0
TTLL13 3176.0
PEX14 3183.0
KIN 3187.0
RRAGA 3202.0
ASGR2 3212.0
XRCC4 3215.0
NUP54 3235.0
NUP210 3259.0
RAB4A 3279.0
DERL1 3316.0
DCTN5 3352.0
AFP 3365.0
ADAMTS7 3389.0
MEN1 3390.0
TUBB6 3395.0
PIGT 3418.0
DNMT3A 3442.0
CD109 3465.0
TRAPPC9 3523.0
HIC1 3527.0
RAB40B 3531.0
TTLL9 3556.0
VWA1 3565.0
EVA1A 3575.0
NR5A2 3584.0
ASB5 3604.0
DDB1 3608.0
CDC20 3609.0
GCNT3 3660.0
RAB31 3666.0
PSMD14 3679.0
FEM1A 3689.0
ETFBKMT 3691.0
DDOST 3732.0
UIMC1 3738.0
RPS2 3762.0
THRB 3789.0
B3GNTL1 3802.0
TTLL1 3812.0
MDGA1 3840.0
ARSG 3841.0
SPTBN4 3843.0
PCSK9 3855.0
SDC2 3882.0
CTSC 3908.0
KLHL22 3910.0
FBN1 3917.0
GLB1 3951.0
UBE2Q2 3955.0
LY6K 3973.0
DDX5 3974.0
B4GALT6 4004.0
SPSB3 4015.0
TRIM28 4029.0
TTLL8 4060.0
ADAMTS13 4066.0
NANS 4096.0
H4C4 4097.0
UBE2G1 4132.0
KDELR1 4190.0
ASB18 4192.0
SMAD2 4200.0
EEF1AKMT1 4239.0
THSD4 4288.0
MTA1 4312.0
OTUB2 4327.0
PSMB6 4375.0
RNF135 4432.0
ENAM 4449.0
FAM20C 4467.0
CFTR 4482.0
PTRH2 4483.0
JOSD2 4525.0
MEPE 4536.0
PIGL 4561.0
THSD1 4567.0
ADAM10 4568.0
FBXW4 4593.0
DCAF4 4594.0
VASH1 4618.0
TADA2B 4665.0
PRND 4673.0
ASXL1 4734.0
LAMB1 4763.0
USP18 4786.0
NUP35 4792.0
BTBD6 4797.0
ST8SIA5 4827.0
IGFBP7 4831.0
ALG3 4845.0
H4C16 4865.0
PEX10 4890.0
CDK1 4923.0
KCTD7 4939.0
RNF123 4970.0
GNPNAT1 4978.0
CUL9 5023.0
GCNT1 5043.0
OTUD7A 5051.0
AGBL2 5089.0
TUBB1 5090.0
ALPL 5096.0
SEC23IP 5103.0
APLP2 5105.0
APOB 5113.0
SMAD1 5151.0
NFKBIA 5179.0
NR1I2 5191.0
FBXL16 5213.0
PIGZ 5218.0
ZBTB16 5227.0
FAM20A 5238.0
GALNT6 5251.0
UBXN1 5266.0
TULP4 5295.0
KDM1B 5343.0
ST6GALNAC3 5346.0
TF 5380.0
AGBL4 5403.0
H4C6 5430.0
OTUD7B 5439.0
ADAMTSL4 5444.0
NUP62 5471.0
TTLL12 5479.0
TTLL7 5508.0
AGBL3 5521.0
FBXO10 5525.0
EPAS1 5562.0
SMURF2 5581.0
RAB8A 5599.0
SEM1 5631.0
SBSPON 5648.0
LYPD4 5656.0
COMMD5 5671.0
RECK 5716.0
MAN1B1 5726.0
TP53 5757.0
PIGG 5784.0
SHPRH 5817.0
TTLL10 5818.0
RAB5C 5853.0
MUC12 5855.0
USP10 5891.0
TRAF3 5900.0
C3 5919.0
LARGE1 5953.0
QSOX1 5968.0
DYNLL2 5999.0
STC2 6008.0
TUBA4B 6042.0
DOLPP1 6049.0
KDELR3 6065.0
GPS1 6067.0
ST3GAL3 6070.0
PRSS21 6081.0
KNG1 6104.0
PHC1 6131.0
ANKRD9 6151.0
B4GALT2 6166.0
PSMD4 6169.0
ASB4 6184.0
CGA 6197.0
PTP4A2 6213.0
ST6GAL1 6241.0
UBA52 6282.0
SNX3 6298.0
EID3 6324.0
ST6GALNAC4 6344.0
RTN4RL1 6354.0
TUBB4A 6369.0
LARGE2 6371.0
TNIP1 6391.0
RNF5 6401.0
MATN3 6413.0
GALNT14 6467.0
MUC6 6518.0
ADAMTS4 6523.0
CHST4 6546.0
IGFBP5 6576.0
F10 6594.0
BGLAP 6602.0
SPTB 6610.0
F2 6618.0
RWDD3 6627.0
SELENOS 6644.0
TUBA4A 6664.0
ADAMTSL5 6674.0
CNIH3 6679.0
RNF40 6689.0
FBXO44 6762.0
RAB19 6774.0
RAB27A 6783.0
PSMD5 6795.0
FBXO15 6799.0
ADAMTS2 6822.0
LY6E 6839.0
VNN2 6843.0
FN3K 6919.0
TUBB3 6928.0
USP8 6959.0
RELA 6961.0
HIF3A 6965.0
RAB15 6974.0
NR5A1 6978.0
MUC5B 6990.0
PROC 7142.0
B3GNT5 7181.0
APOE 7188.0
COMMD7 7296.0
SEMA5B 7298.0
GGCX 7321.0
FGG 7327.0
NTNG2 7332.0
SEC16B 7343.0
FOXL2 7346.0
ASB14 7357.0
TRAPPC5 7367.0
APOA5 7372.0
FBXL14 7403.0
AHSG 7404.0
IKBKE 7420.0
WFS1 7430.0
TECTA 7528.0
ST6GALNAC6 7556.0
A4GNT 7575.0
LGALS1 7590.0
SPSB4 7644.0
RAB6B 7654.0
GFPT2 7668.0
C4A 7670.5
ALPG 7697.0
LYPD6B 7706.0
GALNT18 7828.0
CD52 7841.0
MUC20 7866.0
SPARCL1 7917.0
TUBB2B 7929.0
ADAMTS8 7952.0
FBXO41 7967.0
RTN4RL2 7988.0
ADAMTS14 8069.0
TTLL11 8091.0
TUBA8 8140.0
GALNT16 8156.0
GALNT15 8210.0
USP2 8213.0
ANK1 8240.0
UBD 8287.0
CCDC8 8289.0
MXRA8 8294.0
GOLM1 8304.0
POM121C 8315.0
CCN1 8339.0
OBSL1 8359.0
NAPG 8360.0
PRSS41 8376.0
CST3 8383.0
B3GNT9 8396.0
FBXO17 8424.0
ABRAXAS2 8446.0
MUC21 8470.0
FGF23 8471.0
LY6D 8499.0
FSTL1 8542.0
SPTBN2 8546.0
ST3GAL5 8547.0
GALNTL5 8550.0
NOTUM 8559.0
TECTB 8563.0
MGAT3 8571.0
LAMB2 8606.0
LY6G6D 8636.0
SSPOP 8652.0
NEU2 8696.0
NUDT14 8697.0
IGFBP1 8706.0
FBXO2 8744.0
GP2 8780.0
ADRB2 8786.0
UBE2C 8787.0
FBXO40 8789.0
ARSI 8824.0
RAB42 8830.0
ALPI 8877.0
GPIHBP1 8879.0
ST8SIA2 8888.0
CEACAM5 8889.0
PIGO 8918.0
RAB3B 8979.0
FKBP8 8994.0
RAB17 9002.0
LYPD3 9048.0
B4GAT1 9064.0
RAB12 9080.0
MUC4 9138.0
SPACA4 9150.0
LYPD2 9151.0
TTLL6 9242.0
NEU4 9270.0
TMEM132A 9282.0
VDR 9296.0
LY6G6C 9308.0
SPON2 9340.0
FBXW10 9360.0
PSCA 9364.0
INS 9369.0
FOLR1 9375.0
PSMB11 9506.0
FBXW12 9514.0
OTOA 9548.0
TUBB8 9559.0
SPSB1 9582.0
ASB16 9595.0
ART4 9616.0
F7 9630.0
ST6GALNAC1 9631.0
B3GNT6 9682.0
ADAMTSL2 9698.0
UCHL1 9707.0
THY1 9775.0
COPZ2 9777.0
ST6GALNAC2 9794.0
SPRN 9878.0
SPTBN5 9882.0
VNN1 9909.0
RAET1L 9918.0
MUC5AC 9976.0
LMAN1L 9979.0
PREB 9994.0
CHML 9999.0
TEX101 10009.0
FUOM 10033.0
FBXO27 10069.0
ASB10 10088.0
CEACAM7 10184.0
ASGR1 10201.0
COL7A1 10204.0
RAB25 10372.0
HRC 10576.0
LYPD8 10605.0
B3GNT7 10659.0


REACTOME_HDACS_DEACETYLATE_HISTONES

REACTOME_HDACS_DEACETYLATE_HISTONES
548
set REACTOME_HDACS_DEACETYLATE_HISTONES
setSize 85
pANOVA 4.55e-12
s.dist -0.434
p.adjustANOVA 3.11e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
H2AC12 -10676.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
H2AC15 -9502.0
H2BC26 -9346.0
H2BC4 -9285.0
GPS2 -9206.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
H2AC12 -10676.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
H2AC15 -9502.0
H2BC26 -9346.0
H2BC4 -9285.0
GPS2 -9206.0
ARID4A -9035.0
H2BC9 -9020.5
H3C7 -9020.5
H2AC13 -8863.0
H2BC3 -8572.0
H4C3 -8451.0
H2AC6 -8428.0
SAP30 -8418.0
H2BC10 -8174.0
SAP18 -8083.0
HDAC10 -7850.0
ARID4B -7690.0
H4C11 -7658.0
H2BC13 -7580.0
H3C1 -7492.0
H2AC21 -7400.0
H2BC5 -7339.0
RBBP4 -7271.0
KDM1A -7160.0
MTA2 -7100.0
GATAD2B -7010.0
H2BC1 -6434.0
H2AC25 -6343.0
PHF21A -6152.0
NCOR2 -6078.0
HDAC1 -5913.0
MBD3 -5490.0
H2BC8 -5414.0
H3C4 -5404.0
BRMS1 -5339.0
H2AC4 -4647.0
H3C8 -4535.0
SUDS3 -4430.0
TBL1XR1 -4414.0
HDAC2 -4377.0
H2BC11 -4063.0
H2AC1 -3983.0
H4C13 -3564.0
CHD3 -3438.0
RCOR1 -3356.0
HMG20B -3275.0
H2AC17 -3211.0
HDAC3 -2723.0
H4C2 -2432.0
CHD4 -1434.0
H2AC11 -1249.0
H2AC8 -1109.0
H4C12 -107.0
H4C1 323.0
H2AC16 397.0
H4C8 685.0
H2BC17 842.0
H3C11 1739.0
H3C10 2461.0
H4C5 2528.0
GATAD2A 2784.0
SAP30L 3412.0
H3C2 3733.0
NCOR1 3766.0
H4C4 4097.0
MTA1 4312.0
MTA3 4544.0
REST 4619.0
H4C16 4865.0
H4C6 5430.0


REACTOME_UB_SPECIFIC_PROCESSING_PROTEASES

REACTOME_UB_SPECIFIC_PROCESSING_PROTEASES
1004
set REACTOME_UB_SPECIFIC_PROCESSING_PROTEASES
setSize 187
pANOVA 4.86e-12
s.dist -0.293
p.adjustANOVA 3.2e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
H2AC14 -10727.0
H2AC12 -10676.0
TGFBR1 -10661.0
PSMB7 -10651.0
PSMC6 -10621.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H2BC12 -10245.0
PSMD2 -10209.0
H2AC20 -10208.0
H2BC15 -10189.0
PSMC2 -10087.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
BECN1 -9853.0
PSMA3 -9831.0
GATA3 -9812.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
H2AC14 -10727.0
H2AC12 -10676.0
TGFBR1 -10661.0
PSMB7 -10651.0
PSMC6 -10621.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H2BC12 -10245.0
PSMD2 -10209.0
H2AC20 -10208.0
H2BC15 -10189.0
PSMC2 -10087.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
BECN1 -9853.0
PSMA3 -9831.0
GATA3 -9812.0
WDR48 -9688.0
PSMB8 -9616.0
H2AC15 -9502.0
ATXN7 -9430.0
PSME1 -9420.0
SIAH2 -9404.0
H2BC26 -9346.0
PSMC5 -9310.0
H2BC4 -9285.0
PSMA8 -9037.0
H2BC9 -9020.5
H2AC13 -8863.0
TOMM70 -8822.0
PSME3 -8645.0
H2BC3 -8572.0
PSMD3 -8488.0
RCE1 -8445.0
H2AC6 -8428.0
RNF146 -8379.0
UBC -8277.0
H2BC10 -8174.0
MAT2B -8135.0
SMAD3 -8098.0
USP19 -8077.0
USP13 -8054.0
PSMD6 -8047.0
USP47 -8019.0
CCP110 -8007.0
USP21 -7965.0
IFIH1 -7904.0
WDR20 -7859.0
TAF10 -7853.0
RHOT1 -7738.0
BIRC3 -7652.0
H2BC13 -7580.0
TRAF2 -7574.0
PSMB10 -7549.0
PSMD7 -7470.0
SMAD4 -7434.0
H2AC21 -7400.0
PSMB5 -7376.0
H2BC5 -7339.0
RIPK1 -7072.0
TADA3 -7021.0
MAP3K7 -7012.0
PSMB2 -7000.0
PSMB9 -6985.0
PSMD9 -6972.0
CDC25A -6793.0
CCNA2 -6534.0
BIRC2 -6460.0
H2BC1 -6434.0
H2AC25 -6343.0
PSMC3 -6093.0
SKP2 -5945.0
PSMD13 -5903.0
USP30 -5713.0
DDB2 -5674.0
H2BC8 -5414.0
USP22 -5401.0
IDE -5400.0
RIGI -5177.0
PSMA2 -5113.0
USP37 -5085.0
PSMD8 -5084.0
USP48 -5013.0
TNKS -4997.0
ARRB1 -4907.0
TNKS2 -4789.0
H2AC4 -4647.0
PSMA1 -4584.0
PTEN -4562.0
SUDS3 -4430.0
H2BC11 -4063.0
ADRM1 -4028.0
PSMB3 -4011.0
TRAF6 -3985.0
H2AC1 -3983.0
PSME4 -3807.0
POLB -3527.0
USP3 -3327.0
USP34 -3242.0
H2AC17 -3211.0
PSMB1 -3117.0
TOMM20 -2897.0
PSMA7 -2759.0
MDM4 -2718.0
UFD1 -2657.0
USP42 -2565.0
PSMF1 -2512.0
CLSPN -2497.0
VDAC1 -2235.0
VDAC3 -2210.0
USP49 -2105.0
SMAD7 -2103.0
CYLD -1843.0
PSMC1 -1839.0
PSMA6 -1800.0
STAM2 -1567.0
USP20 -1420.0
RUVBL1 -1380.0
USP24 -1359.0
H2AC11 -1249.0
VDAC2 -1153.0
USP12 -1130.0
H2AC8 -1109.0
USP28 -1074.0
CCNA1 -948.0
PSMD1 -818.0
USP14 -772.0
MYC -745.0
UBB -665.0
PSMA4 -648.0
USP33 -506.0
KEAP1 -351.0
TRRAP -217.0
RPS27A -126.0
USP44 -5.0
MDM2 136.0
USP25 140.0
TAB1 262.0
USP7 268.0
USP15 387.0
H2AC16 397.0
HGS 680.0
MUL1 831.0
USP4 835.0
H2BC17 842.0
IL33 865.0
USP16 929.0
PSMD11 1023.0
HIF1A 1245.0
PSMB4 1285.0
PSMA5 1304.0
KAT2A 1331.0
PSMC4 1596.0
USP5 1701.0
AXIN2 1970.0
OTUB1 2018.0
PSME2 2084.0
ARRB2 2582.0
PSMD12 2806.0
AXIN1 3098.0
CDC20 3609.0
PSMD14 3679.0
SMAD2 4200.0
PSMB6 4375.0
CFTR 4482.0
PTRH2 4483.0
TADA2B 4665.0
USP18 4786.0
RNF123 4970.0
SMAD1 5151.0
NFKBIA 5179.0
SMURF2 5581.0
SEM1 5631.0
TP53 5757.0
USP10 5891.0
PSMD4 6169.0
UBA52 6282.0
SNX3 6298.0
PSMD5 6795.0
USP8 6959.0
USP2 8213.0
ADRB2 8786.0
FKBP8 8994.0
PSMB11 9506.0


REACTOME_SIGNALING_BY_GPCR

REACTOME_SIGNALING_BY_GPCR
593
set REACTOME_SIGNALING_BY_GPCR
setSize 673
pANOVA 8.8e-12
s.dist 0.154
p.adjustANOVA 5.55e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
MLN 10633
TAC3 10566
UCN2 10554
WNT8A 10553
GHRHR 10508
LPAR5 10498
CHRM4 10490
CCL22 10472
GNGT2 10448
CCL19 10427
GHRH 10420
CCL13 10381
TAS1R3 10377
MLNR 10345
CCL5 10328
PROKR1 10320
GPR25 10318
PPY 10304
TAS2R41 10261
GALR3 10243

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MLN 10633
TAC3 10566
UCN2 10554
WNT8A 10553
GHRHR 10508
LPAR5 10498
CHRM4 10490
CCL22 10472
GNGT2 10448
CCL19 10427
GHRH 10420
CCL13 10381
TAS1R3 10377
MLNR 10345
CCL5 10328
PROKR1 10320
GPR25 10318
PPY 10304
TAS2R41 10261
GALR3 10243
TAS2R13 10223
CCL27 10220
GNAT2 10170
NPW 10146
HCRTR1 10123
INSL5 10093
PROK1 10059
GNB3 10044
UCN 10040
CCR3 10028
GNG11 10008
WNT9B 9984
CCL17 9933
CAMK2A 9899
CCL16 9860
GPR37L1 9855
CXCR2 9804
CCL20 9802
RAMP3 9780
ARHGEF10L 9772
RGS11 9719
SCT 9710
GPR31 9705
HCAR1 9676
GLP1R 9640
PPBP 9636
UTS2R 9612
HTR4 9590
ADORA1 9584
ARHGEF15 9572
ARHGEF25 9568
LPAR1 9544
ADRA1D 9502
TACR2 9481
P2RY6 9474
CX3CL1 9438
GPR55 9434
GPR4 9432
ARHGEF19 9430
ADORA2A 9421
GPR32 9418
PRLH 9415
TAS2R60 9409
TAS2R14 9398
RLN3 9370
ACKR2 9333
MMP3 9327
CHRM1 9309
KEL 9303
RAMP2 9301
CCL11 9274
WNT7A 9272
CXCL9 9241
MCHR1 9232
XCL1 9205
C5AR2 9180
DAGLA 9157
CCR2 9141
POMC 9122
WNT9A 9103
CORT 9076
TAS1R2 9047
SCTR 9021
NGEF 9010
RGS8 8927
FFAR4 8900
PTAFR 8896
MGLL 8895
CCR9 8857
ADCY5 8848
UTS2 8803
ADRB2 8786
GRM4 8768
ARHGEF37 8765
TAS1R1 8724
CXCR1 8715
FFAR1 8694
GNRH2 8686
TAAR1 8667
FZD4 8661
VIP 8660
CCR6 8634
HTR1D 8622
NBEA 8613
ADCY6 8590
IAPP 8531
CCRL2 8523
GPR84 8508
CXCR5 8494
CCL2 8464
CCL1 8429
PTH1R 8423
CX3CR1 8393
QRFP 8344
PTGIR 8327
NPY2R 8307
MC1R 8260
PYY 8254
ADCYAP1R1 8236
CRHR1 8198
NPFFR1 8139
ARHGEF38 8128
OXER1 8118
ACKR4 8111
WNT2B 8079
GABBR2 8074
CCKAR 8039
PDE2A 7987
NMUR1 7976
ADCY1 7939
CMKLR1 7904
C3AR1 7878
SRC 7873
NPY 7862
HRH1 7820
GCG 7768
ADGRE1 7728
PLXNB1 7686
AGT 7651
CXCL16 7609
GNAT1 7584
ABHD6 7581
GPR20 7532
CXCL5 7515
GNGT1 7502
NTSR1 7446
PRKAR2B 7419
GPR39 7384
RHO 7351
KISS1 7299
ADM2 7293
DRD2 7269
OPN3 7200
CCL7 7186
S1PR3 7183
NPBWR2 7174
GPR132 7143
CAMKK1 7141
PDE8B 7139
AGTR1 7090
PLPPR3 7070
RLN2 7058
TAC1 7056
P2RY2 7022
CAMK2B 7010
PRKAR2A 7000
PDYN 6987
AVP 6951
PTH2 6905
ARHGEF11 6851
GPR45 6840
GRM2 6824
RGS13 6815
GPR183 6794
TAS2R39 6742
TRIO 6739
PIK3R6 6729
RGS22 6727
ARHGEF33 6723
TACR1 6709
EDNRB 6681
PLEKHG5 6663
GRM6 6658
RXFP4 6648
XCR1 6621
F2 6618
CRHR2 6613
UTS2B 6611
TRHR 6603
GNG13 6596
PLPPR2 6562
CXCL12 6390
RGS12 6359
PDE3B 6306
WNT16 6259
DRD4 6240
CCR5 6200
CGA 6197
GNA11 6170
MC5R 6125
PDE1B 6111
KNG1 6104
GNAI1 6095
LPAR3 6066
GRK5 6060
SSTR4 6055
SMO 6045
GPR176 5990
CALCR 5980
PPP1CA 5964
DGKG 5952
GPR150 5922
C3 5919
ECE2 5899
WNT3A 5870
CASR 5869
GABBR1 5842
CXCL2 5815
GPR68 5731
RGS16 5715
GPR17 5695
TAAR5 5686
IHH 5594
FSHR 5546
BDKRB1 5480
OBSCN 5397
VAV2 5364
PRKCE 5354
GPR35 5277
HTR1E 5261
FFAR3 5243
WNT7B 5065
ARHGEF17 4942
GIPR 4882
GALR2 4839
GALR1 4770
TAS2R5 4699
PNOC 4689
BDKRB2 4679
PDE4C 4657
OPRL1 4656
GPR27 4632
PREX1 4631
GNG2 4615
PSAP 4611
MC3R 4559
GRK6 4490
ADCY4 4464
PRKCH 4445
NPY1R 4439
HTR1F 4430
VIPR1 4374
UCN3 4366
ARHGEF4 4336
RXFP1 4321
GNG12 4316
GPER1 4314
CCR10 4310
CCK 4301
WNT2 4297
ARHGEF10 4267
GNB2 4244
MCF2L 4198
PRKACG 4191
CXCL1 4149
KISS1R 4131
CCL28 4119
TAAR9 4047
PLCB3 4046
PLCB1 4042
PDE4A 4018
RASGRP2 3990
PTGDR 3939
PDE11A 3937
PDE4D 3928
NPB 3833
WNT10A 3823
F2R 3760
PTH2R 3742
RPS6KA2 3715
GRK3 3684
GNA15 3683
OPRD1 3682
DRD5 3605
P2RY11 3601
NMU 3560
RGS2 3530
PRKCQ 3513
EGFR 3462
CXCL13 3454
GNA14 3439
CNR2 3402
PTCH2 3401
WNT6 3388
GNG7 3330
PTCH1 3310
RGSL1 3300
P2RY12 3278
WNT4 3225
RHOC 3214
GNG8 3100
NPY5R 3097
GNAI2 3078
TAS2R8 3022
ITSN1 3008
DGKQ 3005
KALRN 3001
FGD4 2999
LPAR2 2993
DGKZ 2983
PAK1 2967
PLEKHG2 2907
TAS2R40 2879
F2RL1 2813
PRKACA 2782
NMB 2741
NPBWR1 2709
GNG5 2685
RGS6 2653
KPNA2 2633
CCL3 2612
GNB4 2592
WNT11 2584
ARRB2 2582
GPR83 2550
PDE8A 2532
ADRA1B 2520
ARHGEF39 2514
GNAL 2506
ADRB1 2501
NTS 2442
RAMP1 2387
ITGA5 2279
CALCA 2200
RGR 2181
TRPC7 2145
WNT3 2143
ADCY9 2100
GRM7 2098
PF4 2093
ARHGEF40 2031
CALCRL 1973
TIAM2 1946
RASGRF2 1940
GRM8 1911
ADCY3 1855
NTSR2 1837
ACKR1 1835
CHRM2 1826
GRM1 1821
GAST 1746
GNRH1 1735
WNT10B 1637
PTGER1 1586
INSL3 1447
CAMK2G 1409
GAL 1395
EDN3 1384
PLCB4 1344
PTGER4 1291
VIPR2 1257
FZD3 1239
CCR7 1236
DGKI 1231
EDN1 1227
AKT3 1209
ADRA2A 1181
ADRA2B 1141
CHRM3 1114
SSTR1 1013
MC2R 1001
EDNRA 943
RGS3 930
CCL21 902
PDE1C 866
PRKAR1B 854
DGKA 809
PRKCA 781
ADCY7 771
ARHGEF3 748
TIAM1 739
TSHR 707
OPN1SW 689
OXGR1 633
GNG4 613
PPP2R5D 498
TAS2R4 478
AKAP13 425
GPSM1 399
RGS20 357
HCRT 328
SSTR2 327
ARHGEF7 259
PDE10A 232
CCL23 230
OXTR 208
P2RY14 182
ARHGEF2 121
CAMK2D 13
PRKCB 3
C5AR1 -26
FZD5 -48
HCAR2 -62
PPP2CA -76
APLNR -178
PPP2CB -279
PTGFR -308
WNT1 -316
PRKACB -341
PTHLH -382
HTR6 -421
PIK3R3 -463
PLPPR5 -565
OPN5 -578
RHOB -613
TBXA2R -618
S1PR1 -631
ADCY8 -691
CALM1 -694
HRH2 -737
PTH -749
PRKCD -789
GPR65 -821
ARHGEF26 -822
HTR2A -829
RGS17 -836
ECE1 -859
ABHD12 -882
EDN2 -945
GNB1 -959
OPRM1 -1005
PPP3CB -1070
FZD9 -1081
GNAZ -1136
HRAS -1272
PIK3R5 -1280
NLN -1281
RGS10 -1295
S1PR4 -1318
ITPR3 -1366
S1PR5 -1411
HTR2B -1494
RHOA -1526
TAAR6 -1575
ADRA2C -1621
GPSM3 -1624
DGKD -1658
P2RY13 -1660
CXCR4 -1674
PRKCG -1792
PDE7A -1853
PLA2G4A -1913
TRPC3 -1948
PIK3CG -1966
SHH -1986
HTR5A -1989
PPP1R1B -2082
LTB4R -2130
PMCH -2149
CREB1 -2161
GNRHR -2176
RGS9 -2177
GRM5 -2204
ECT2 -2226
AKT1 -2241
DHH -2251
GNAT3 -2264
PPP2R1A -2279
C5 -2310
CXCR6 -2426
TAS2R46 -2440
RGS14 -2507
TRPC6 -2666
PCP2 -2678
RXFP2 -2699
PDE4B -2746
FGD3 -2815
PRKAR1A -2835
CCKBR -2902
CDK5 -2911
PPP3CC -2936
AHCYL1 -3022
AVPR1A -3043
HRH3 -3056
MAPK3 -3089
MAPK1 -3156
TAS2R1 -3184
FZD7 -3253
TAS2R19 -3256
CNR1 -3288
GLP2R -3309
NMS -3349
GIP -3350
ADRB3 -3367
ADGRE5 -3443
MTNR1B -3446
CXCL3 -3451
FPR3 -3459
ADGRE2 -3496
ADORA3 -3509
PDE7B -3554
ARHGEF16 -3605
GPR37 -3635
DAGLB -3638
ADGRE3 -3640
GNB5 -3644
DGKH -3718
TAS2R50 -3737
PPP2R1B -3830
CHRM5 -3841
TRH -3869
VAV3 -3870
MAPK7 -3897
CXCL11 -3898
LHCGR -3915
ABR -4038
ADRA1A -4065
QRFPR -4101
GPHB5 -4119
SUCNR1 -4133
PLPPR4 -4143
HEBP1 -4246
PENK -4279
GNA13 -4290
DRD1 -4293
GNAI3 -4432
CCR4 -4444
ANXA1 -4452
PLPPR1 -4539
PDPK1 -4559
ITGB1 -4570
RGS19 -4644
SOS2 -4650
RXFP3 -4651
CAMK4 -4746
PDE3A -4846
PROK2 -4868
SOS1 -4879
ARRB1 -4907
GHSR -4922
PPP3CA -4939
RGS5 -4952
S1PR2 -5023
DGKE -5181
TAS2R20 -5195
APP -5218
CRH -5220
FN1 -5229
AVPR1B -5243
RGS4 -5308
NMUR2 -5317
FZD8 -5369
SST -5379
WNT5A -5461
FPR2 -5517
GPBAR1 -5538
DRD3 -5541
NPFFR2 -5562
ADCY2 -5626
GRB2 -5691
RGS21 -5711
TAS2R30 -5747
HTR7 -5809
CD55 -5994
NPSR1 -5997
CAMKK2 -6010
LTB4R2 -6070
ARHGEF18 -6085
OPN4 -6111
GNAQ -6131
FFAR2 -6188
HBEGF -6218
AKT2 -6287
FZD1 -6349
PDE1A -6399
PTGER3 -6420
GPRC6A -6450
CXCL6 -6452
TSHB -6594
TAAR2 -6612
NPFF -6680
FZD6 -6686
HCRTR2 -6780
TAS2R38 -6990
ITPR2 -7172
FPR1 -7227
ROCK1 -7387
ARHGEF1 -7485
TAS2R42 -7527
PROKR2 -7528
MTNR1A -7596
CCL25 -7600
LPAR6 -7655
MCHR2 -7692
CCR8 -7760
ITPR1 -7781
GRK2 -7788
P2RY1 -7798
HTR1A -7875
MC4R -7897
TAS2R9 -7939
RGS1 -7949
FZD2 -8031
NET1 -8059
ADM -8101
SAA1 -8169
WNT8B -8185
CALCB -8248
SSTR3 -8361
PPP3R1 -8472
RRH -8495
GNG3 -8510
XCL2 -8522
GNG10 -8561
ARHGEF12 -8643
GPR18 -8731
TAS2R7 -8736
F2RL2 -8795
DGKB -8810
PIK3R1 -8817
ADORA2B -8845
GPSM2 -8852
CXCL8 -8858
CCR1 -8936
RGS18 -8959
RGS7 -8966
ADCYAP1 -9043
VAV1 -9148
ROCK2 -9424
F2RL3 -9428
NRAS -9480
GRP -9489
RASGRP1 -9571
SSTR5 -9590
CDC42 -9607
GRM3 -9668
PIK3CA -9680
PTGER2 -9686
KRAS -9725
TAS2R43 -9752
NPS -9769
PIK3R2 -9856
TAS2R16 -9876
PTGDR2 -9903
GHRL -10066
GPHA2 -10079
NMBR -10107
HTR1B -10130
RPS6KA1 -10164
OPRK1 -10174
FZD10 -10260
GNA12 -10305
TACR3 -10390
PRLHR -10409
FGD2 -10464
TAS2R31 -10471
LHB -10472
PLCB2 -10501
GNAS -10554
ACKR3 -10691
CYSLTR2 -10747
TAS2R3 -10750
SHC1 -10869
FSHB -10894
CXCL10 -10962
TAS2R10 -11012
TAAR8 -11090
CRHBP -11111
OXT -11123
HRH4 -11167
ARHGEF5 -11168
GPR15 -11178
CCL4 -11241


REACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS

REACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS
1476
set REACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS
setSize 83
pANOVA 1.16e-11
s.dist -0.431
p.adjustANOVA 7.07e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
SPI1 -10569.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
TAL1 -10125.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
EP300 -9652.0
H2BC26 -9346.0
H2BC4 -9285.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
SPI1 -10569.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
TAL1 -10125.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
EP300 -9652.0
H2BC26 -9346.0
H2BC4 -9285.0
MYB -9069.0
H2BC9 -9020.5
H3C7 -9020.5
GATA2 -8618.0
H2BC3 -8572.0
H4C3 -8451.0
H2AC6 -8428.0
STAT3 -8252.0
RUNX1 -8234.0
H2BC10 -8174.0
CBFB -7940.0
CDK2 -7826.0
H4C11 -7658.0
H2BC13 -7580.0
H3C1 -7492.0
H2BC5 -7339.0
CEBPA -7336.0
TFDP2 -7095.0
IL6R -6901.0
H2BC1 -6434.0
DEK -6397.0
KMT2A -6224.0
CEBPB -6129.0
H3-3B -5536.0
PML -5486.0
H2BC8 -5414.0
H3C4 -5404.0
H3-3A -5377.0
TFDP1 -5000.0
H2AC4 -4647.0
H3C8 -4535.0
GFI1 -4343.0
H2BC11 -4063.0
E2F1 -3673.0
H4C13 -3564.0
KLF5 -2966.0
CEBPE -2594.0
H4C2 -2432.0
CREB1 -2161.0
H2AZ2 -1872.0
LEF1 -1871.0
RARA -1743.0
CDKN1A -1607.0
H2AC8 -1109.0
H2AJ -963.0
MYC -745.0
H4C12 -107.0
H4C1 323.0
H4C8 685.0
RXRA 721.0
H2BC17 842.0
H2AX 876.0
CDK4 1550.0
H3C11 1739.0
H3C10 2461.0
H4C5 2528.0
FLI1 2881.0
H3C2 3733.0
H4C4 4097.0
H2AZ1 4397.0
H4C16 4865.0
H4C6 5430.0
CSF3R 6367.0


REACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION

REACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION
1279
set REACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION
setSize 90
pANOVA 1.87e-11
s.dist -0.409
p.adjustANOVA 1.1e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
NFE2 -11221.0
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
ASH2L -10434.0
MIR27A -10381.0
H2BC6 -10375.0
GP1BA -10343.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
MOV10 -10287.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NFE2 -11221.0
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
ASH2L -10434.0
MIR27A -10381.0
H2BC6 -10375.0
GP1BA -10343.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
MOV10 -10287.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
EP300 -9652.0
H2BC26 -9346.0
H2BC4 -9285.0
H2BC9 -9020.5
H3C7 -9020.5
KMT2C -8999.0
SIN3A -8665.0
H2BC3 -8572.0
H4C3 -8451.0
H2AC6 -8428.0
RUNX1 -8234.0
H2BC10 -8174.0
PRMT1 -8128.0
CBFB -7940.0
SIN3B -7729.0
TNRC6B -7724.0
H4C11 -7658.0
H2BC13 -7580.0
AGO4 -7579.0
H3C1 -7492.0
H2BC5 -7339.0
KAT2B -7302.0
SETD1A -6967.0
H2BC1 -6434.0
KMT2A -6224.0
HDAC1 -5913.0
DPY30 -5759.0
H3-3B -5536.0
H2BC8 -5414.0
PRMT6 -5405.0
H3C4 -5404.0
H3-3A -5377.0
H2AC4 -4647.0
H3C8 -4535.0
NR4A3 -4475.0
H2BC11 -4063.0
WDR5 -4056.0
H4C13 -3564.0
AGO3 -3073.0
KMT2E -2841.0
THBS1 -2605.0
H4C2 -2432.0
RBBP5 -2037.0
H2AZ2 -1872.0
ZFPM1 -1594.0
H2AC8 -1109.0
H2AJ -963.0
SETD1B -490.0
TNRC6A -436.0
H4C12 -107.0
KMT2D 302.0
H4C1 323.0
AGO1 376.0
H4C8 685.0
H2BC17 842.0
H2AX 876.0
H3C11 1739.0
PF4 2093.0
H3C10 2461.0
H4C5 2528.0
TNRC6C 3185.0
PRKCQ 3513.0
H3C2 3733.0
H4C4 4097.0
H2AZ1 4397.0
MYL9 4856.0
H4C16 4865.0
H4C6 5430.0
ITGA2B 7936.0
KMT2B 9075.0


REACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53

REACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53
591
set REACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53
setSize 351
pANOVA 2e-11
s.dist -0.208
p.adjustANOVA 1.14e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
L3MBTL1 -11185
CNOT11 -10716
RRM2B -10668
MEAF6 -10616
CASP6 -10602
TXN -10530
COX18 -10439
MOV10 -10287
CNOT6L -10244
BRCA1 -10206
CSNK2A2 -9986
LAMTOR3 -9915
ELOB -9858
SUPT16H -9810
GADD45A -9677
EP300 -9652
CCNE2 -9649
MAPK14 -9643
MAP2K6 -9611
HUS1 -9493

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
L3MBTL1 -11185
CNOT11 -10716
RRM2B -10668
MEAF6 -10616
CASP6 -10602
TXN -10530
COX18 -10439
MOV10 -10287
CNOT6L -10244
BRCA1 -10206
CSNK2A2 -9986
LAMTOR3 -9915
ELOB -9858
SUPT16H -9810
GADD45A -9677
EP300 -9652
CCNE2 -9649
MAPK14 -9643
MAP2K6 -9611
HUS1 -9493
PIN1 -9485
ERCC3 -9371
NELFB -9365
TP53I3 -9321
TP53BP2 -9317
YWHAZ -9228
CASP10 -9224
SCO2 -9217
PLK3 -9091
SCO1 -9085
LAMTOR2 -8879
ZNF420 -8767
TP53RK -8749
EXO1 -8718
CDK12 -8566
BAX -8467
GTF2H3 -8449
COX7A2L -8438
LAMTOR4 -8388
PRKAA1 -8315
PCNA -8301
BNIP3L -8294
UBC -8277
RMI2 -8269
TAF3 -8256
CNOT1 -8226
PRMT1 -8128
KAT5 -8114
KMT5A -8065
SETD9 -8040
RAD9A -8023
TMEM219 -8017
COX11 -7946
FAS -7922
RFFL -7908
PLAGL1 -7863
TAF10 -7853
CDK2 -7826
KAT6A -7825
ERCC2 -7814
NPM1 -7766
CSNK2B -7734
TNRC6B -7724
MRE11 -7695
GTF2H1 -7675
MNAT1 -7673
RFC3 -7597
RNF34 -7588
AGO4 -7579
CCNH -7537
CCNT2 -7431
CTDP1 -7416
CNOT3 -7373
NBN -7344
CNOT6 -7337
YWHAG -7293
COX4I1 -7276
RBBP4 -7271
CDC25C -7260
ELL -7225
CNOT2 -7216
MAPKAPK5 -7178
BLM -7176
ING2 -7113
MTA2 -7100
TFDP2 -7095
GATAD2B -7010
IGFBP3 -7002
POLR2H -6881
PHF20 -6767
TAF15 -6684
TAF2 -6681
JMY -6626
PRKAG1 -6548
CCNA2 -6534
CDKN1B -6381
AKT2 -6287
TP63 -6146
COX20 -6100
SESN3 -6092
TAF1L -6049
POLR2L -5972
HDAC1 -5913
BRPF1 -5911
CDKN2A -5841
COX19 -5834
E2F7 -5830
SLC38A9 -5681
DDB2 -5674
POLR2K -5634
CRADD -5612
APAF1 -5581
CDK13 -5577
RFC4 -5573
ELOA -5519
CCNE1 -5513
POU4F1 -5496
MBD3 -5490
PML -5486
PRELID1 -5476
LAMTOR1 -5340
CDK7 -5280
FANCI -5274
CASP1 -5264
ATRIP -5204
ARID3A -5190
CNOT10 -5184
RRAGC -5175
NELFE -5152
TOPBP1 -5020
GPI -5012
TFDP1 -5000
TTC5 -4896
NDUFA4 -4859
MSH2 -4838
POU4F2 -4833
PRDX2 -4823
AURKA -4806
PRR5 -4624
PTEN -4562
PDPK1 -4559
FANCC -4553
BRD1 -4540
CNOT9 -4525
PMS2 -4508
COX6B1 -4497
NELFCD -4386
HDAC2 -4377
RMI1 -4357
RBBP8 -4231
WRN -4227
GLS2 -4207
CYCS -4168
SMYD2 -4076
RABGGTB -3971
POLR2G -3937
COX5B -3858
PPP2R1B -3830
RHEB -3824
MLH1 -3770
POLR2B -3768
E2F1 -3673
GLS -3609
TAF5 -3594
TAF11 -3452
CHD3 -3438
DDIT4 -3385
PRDX1 -3352
PRDX5 -3225
CNOT4 -3192
GSR -3160
CCNG1 -3154
PRKAB2 -3104
TOP3A -3093
AGO3 -3073
TAF6 -3011
JUN -2945
CASP2 -2919
CDK5 -2911
TNFRSF10B -2888
BRD7 -2802
GTF2F2 -2764
TAF4 -2733
MDM4 -2718
MAPKAP1 -2680
SESN2 -2675
ATM -2668
E2F8 -2632
CARM1 -2380
PERP -2289
PPP2R1A -2279
AKT1 -2241
EHMT2 -2233
PIDD1 -2166
ELOC -2118
COX7C -2020
RPA1 -2002
FANCD2 -1968
TSC2 -1891
RFC5 -1846
TPX2 -1745
RHNO1 -1742
POLR2I -1736
RBL1 -1654
CDKN1A -1607
CREBBP -1603
TP53INP1 -1587
E2F4 -1544
CHD4 -1434
NDRG1 -1371
PIP4K2B -1322
POLR2A -1290
TSC1 -1235
SGK1 -1173
ING5 -1169
STK11 -1167
COX16 -1117
DNA2 -1113
TAF13 -1085
SUPT5H -997
CCNA1 -948
PRKAA2 -936
FOS -894
AIFM2 -835
YWHAE -811
GTF2H5 -806
SURF1 -695
UBB -665
COX6C -638
PPP2R5C -627
RICTOR -564
TBP -483
TNRC6A -436
RAD17 -303
PPP2CB -279
ATR -207
PIP4P1 -164
RPS27A -126
RAD1 -102
PPP2CA -76
MLST8 -52
BARD1 -51
SESN1 -50
AURKB 55
TAF9 76
CNOT8 131
MDM2 136
GTF2H4 183
POLR2C 198
AGO2 199
NOC2L 256
USP7 268
RAD9B 312
COX6A1 341
AGO1 376
RABGGTA 458
TXNRD1 473
BANP 480
POLR2E 503
NELFA 565
YWHAB 626
COX14 690
CHEK2 921
GTF2F1 936
TNKS1BP1 1103
CNOT7 1183
RPA3 1184
MTOR 1189
AKT3 1209
BRIP1 1255
CDK9 1265
RBL2 1308
TNFRSF10D 1364
CCNT1 1385
ELOA2 1535
DAXX 1573
YWHAH 1579
HIPK2 1642
PRKAG2 1729
HIPK1 1879
RFC2 1966
RAD51D 2111
BIRC5 2299
RPA2 2309
PRKAB1 2331
CHEK1 2332
POLR2D 2370
TAF4B 2428
BRPF3 2474
RRAGD 2628
BCL6 2676
GATAD2A 2784
TAF12 2897
BCL2L14 2973
MDC1 2996
YWHAQ 3040
EHMT1 3168
POLR2F 3184
TNRC6C 3185
RRAGA 3202
PMAIP1 3208
ATF2 3306
RPTOR 3471
TACO1 3550
CSNK2A1 3638
CENPJ 3667
TNFRSF10A 3673
POLR2J 3674
PRMT5 3698
LRPPRC 3771
CCNB1 4274
BBC3 4285
NLRC4 4294
TAF7 4352
CCNK 4453
TIGAR 4549
MAPK11 4578
PIP4K2A 4624
PPP1R13B 4709
PRDM1 4922
CDK1 4923
LAMTOR5 5050
ZNF385A 5162
RAD50 5232
TRIAP1 5276
DYRK2 5284
CDK5R1 5516
SUPT4H1 5721
TP53 5757
PCBP4 5764
PLK2 5860
TCEA1 6002
SSRP1 6003
PPP1R13L 6007
BID 6138
COX5A 6246
UBA52 6282
PIP4K2C 6327
NUAK1 6950
PRELID3A 7068
RGCC 7280
TP73 7334
COX8A 7527
TP53AIP1 7872
USP2 8213
STEAP3 8834
GPX2 8949
BTG2 9300
PRKAG3 9613
TNFRSF10C 9624
SFN 10291


REACTOME_RNA_POLYMERASE_I_PROMOTER_ESCAPE

REACTOME_RNA_POLYMERASE_I_PROMOTER_ESCAPE
1157
set REACTOME_RNA_POLYMERASE_I_PROMOTER_ESCAPE
setSize 83
pANOVA 4.13e-11
s.dist -0.419
p.adjustANOVA 2.22e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
RRN3 -10966.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
H2AC20 -10208.0
POLR1E -10205.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
POLR1B -9824.0
ERCC3 -9371.0
H2BC26 -9346.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
RRN3 -10966.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
H2AC20 -10208.0
POLR1E -10205.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
POLR1B -9824.0
ERCC3 -9371.0
H2BC26 -9346.0
H2BC4 -9285.0
H2BC9 -9020.5
H3C7 -9020.5
TAF1B -8830.0
H2BC3 -8572.0
H4C3 -8451.0
GTF2H3 -8449.0
H2AC6 -8428.0
H2BC10 -8174.0
ERCC2 -7814.0
GTF2H1 -7675.0
MNAT1 -7673.0
H4C11 -7658.0
H2BC13 -7580.0
CCNH -7537.0
H3C1 -7492.0
H2BC5 -7339.0
POLR1C -7120.0
POLR2H -6881.0
TAF1D -6750.0
POLR1G -6552.0
H2BC1 -6434.0
POLR2L -5972.0
POLR2K -5634.0
H3-3B -5536.0
H2BC8 -5414.0
H3C4 -5404.0
H3-3A -5377.0
CDK7 -5280.0
H2AC4 -4647.0
H3C8 -4535.0
H2BC11 -4063.0
H4C13 -3564.0
POLR1H -2697.0
POLR1A -2555.0
H4C2 -2432.0
H2AZ2 -1872.0
H2AC8 -1109.0
H2AJ -963.0
CBX3 -932.0
GTF2H5 -806.0
TBP -483.0
TAF1A -129.0
H4C12 -107.0
GTF2H4 183.0
POLR1D 218.0
H4C1 323.0
POLR2E 503.0
H4C8 685.0
H2BC17 842.0
H2AX 876.0
UBTF 1426.0
H3C11 1739.0
POLR1F 1814.0
H3C10 2461.0
TAF1C 2477.0
H4C5 2528.0
POLR2F 3184.0
H3C2 3733.0
H4C4 4097.0
H2AZ1 4397.0
H4C16 4865.0
H4C6 5430.0


REACTOME_MRNA_SPLICING

REACTOME_MRNA_SPLICING
1143
set REACTOME_MRNA_SPLICING
setSize 197
pANOVA 4.24e-11
s.dist -0.272
p.adjustANOVA 2.22e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
SNRPN -11091
PRPF6 -10912
FAM32A -10709
PRCC -10612
ZMAT5 -10078
RBM8A -10008
SLU7 -9843
MAGOHB -9842
MAGOH -9827
U2AF1L4 -9732
HNRNPU -9717
PCBP1 -9650
PRKRIP1 -9544
HNRNPA3 -9498
LSM7 -9451
LSM3 -9276
SRSF8 -9253
RNPC3 -9198
U2SURP -9195
GPATCH1 -9141

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SNRPN -11091
PRPF6 -10912
FAM32A -10709
PRCC -10612
ZMAT5 -10078
RBM8A -10008
SLU7 -9843
MAGOHB -9842
MAGOH -9827
U2AF1L4 -9732
HNRNPU -9717
PCBP1 -9650
PRKRIP1 -9544
HNRNPA3 -9498
LSM7 -9451
LSM3 -9276
SRSF8 -9253
RNPC3 -9198
U2SURP -9195
GPATCH1 -9141
PRPF19 -9140
PPIH -9013
ACIN1 -8816
SRSF11 -8791
PLRG1 -8783
HNRNPA1 -8664
SRSF10 -8621
AQR -8601
CTNNBL1 -8580
WBP11 -8531
DHX35 -8474
SNRNP200 -8455
WBP4 -8359
CWC27 -8217
NCBP1 -8209
SRRM1 -8132
PPP1R8 -8131
SAP18 -8083
SNU13 -8074
LSM5 -7999
CDC40 -7930
DDX23 -7726
SNRPB -7665
PRPF4 -7649
LSM4 -7499
SF3B3 -7426
SNRPB2 -7268
DNAJC8 -7255
BUD31 -7222
YJU2 -7193
HNRNPK -7107
PRPF3 -7055
LENG1 -7009
SART1 -6980
CACTIN -6893
POLR2H -6881
SRSF6 -6815
RBM22 -6693
DHX15 -6668
RBM7 -6601
DHX38 -6598
SNRNP40 -6509
CASC3 -6442
SNRNP27 -6143
HNRNPA2B1 -6137
EFTUD2 -6109
POLR2L -5972
BCAS2 -5923
DDX42 -5805
HSPA8 -5803
SUGP1 -5652
CWC15 -5642
POLR2K -5634
SRSF1 -5591
HNRNPH1 -5540
SRSF5 -5500
SRSF9 -5477
SNRNP70 -5300
SF3A2 -5259
PRPF38A -5148
CWF19L2 -5080
UBL5 -5053
MFAP1 -4901
LSM6 -4786
TRA2B -4639
SRRM2 -4633
SNRPA -4631
PPIL3 -4467
CWC25 -4443
RBM25 -4431
SNRPA1 -4363
HNRNPD -4277
TCERG1 -4147
SDE2 -4118
SNRPD3 -4100
CDC5L -4089
POLR2G -3937
HNRNPM -3894
PCBP2 -3820
POLR2B -3768
ZCRB1 -3735
MTREX -3624
RBM39 -3444
DHX8 -3434
SYF2 -3389
HNRNPL -3278
SF3B1 -3274
HNRNPR -3271
DHX16 -3257
SRSF3 -3037
ZNF830 -2810
DDX46 -2803
SNRPD2 -2767
GTF2F2 -2764
PPWD1 -2653
SF3B6 -2621
WDR70 -2575
NCBP2 -2442
DDX41 -2322
SNRNP35 -2217
SRSF2 -2063
BUD13 -1934
CCAR1 -1820
POLR2I -1736
U2AF2 -1675
RBM17 -1617
PPIG -1581
LSM2 -1573
CHERP -1569
SF1 -1455
SNRPE -1363
POLR2A -1290
PTBP1 -1245
SF3A3 -1166
RBM42 -1060
LUC7L3 -1040
SRSF7 -970
HNRNPC -921
CWC22 -672
PHF5A -537
CCDC12 -467
XAB2 -464
SRSF4 -453
PNN -311
SNIP1 -152
SNRPD1 -139
PDCD7 -93
TXNL4A -12
SNW1 45
LSM8 105
NSRP1 165
POLR2C 198
YBX1 363
ALYREF 481
POLR2E 503
DDX39B 742
FUS 916
GTF2F1 936
PRPF8 962
SNRPG 982
C9orf78 1075
SRRT 1110
SF3B4 1361
HNRNPF 1389
IK 1451
PRPF40A 1662
PRPF31 2074
SF3A1 2123
DHX9 2178
POLR2D 2370
ZMAT2 2436
EIF4A3 2759
GCFC2 3011
POLR2F 3184
PPIL2 3436
SNRPC 3646
POLR2J 3674
DDX5 3974
RNPS1 4053
PPIL4 4125
CRNKL1 4175
PUF60 4461
SF3B2 4465
RBM5 4683
SNRPF 4945
PPIE 5253
SNRNP48 5274
SNRNP25 5356
SMNDC1 5774
PRPF18 5788
TFIP11 5846
USP39 5857
ISY1 6542
SF3B5 6672
PPIL1 7207
SRSF12 8178
SMU1 8799


REACTOME_S_PHASE

REACTOME_S_PHASE
1110
set REACTOME_S_PHASE
setSize 159
pANOVA 4.32e-11
s.dist -0.303
p.adjustANOVA 2.22e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
PSMB7 -10651
PSMC6 -10621
LIN52 -10236
PSMD2 -10209
FZR1 -10150
PSMC2 -10087
RB1 -10080
MCM5 -9953
PRIM2 -9944
LIG1 -9941
PSMA3 -9831
RAD21 -9775
ORC4 -9685
CCNE2 -9649
PSMB8 -9616
PSME1 -9420
PSMC5 -9310
E2F5 -9245
ANAPC16 -9057
PSMA8 -9037

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PSMB7 -10651
PSMC6 -10621
LIN52 -10236
PSMD2 -10209
FZR1 -10150
PSMC2 -10087
RB1 -10080
MCM5 -9953
PRIM2 -9944
LIG1 -9941
PSMA3 -9831
RAD21 -9775
ORC4 -9685
CCNE2 -9649
PSMB8 -9616
PSME1 -9420
PSMC5 -9310
E2F5 -9245
ANAPC16 -9057
PSMA8 -9037
PRIM1 -8994
CDC23 -8726
PSME3 -8645
PSMD3 -8488
CKS1B -8337
PCNA -8301
UBC -8277
POLD3 -8233
ANAPC7 -8113
PSMD6 -8047
LIN54 -7849
CDK2 -7826
MNAT1 -7673
RFC3 -7597
PSMB10 -7549
CCNH -7537
PSMD7 -7470
FEN1 -7452
CDC16 -7384
PSMB5 -7376
POLE4 -7340
RBBP4 -7271
CDC26 -7245
TFDP2 -7095
RFC1 -7068
PSMB2 -7000
PSMB9 -6985
PSMD9 -6972
PDS5B -6842
CDC25A -6793
MCM8 -6756
POLA2 -6677
SKP1 -6672
GINS3 -6647
CCNA2 -6534
PDS5A -6492
CDKN1B -6381
POLD2 -6366
ANAPC5 -6314
AKT2 -6287
ESCO2 -6260
ORC3 -6201
UBE2E1 -6123
WAPL -6116
PSMC3 -6093
SKP2 -5945
PSMD13 -5903
UBE2S -5833
GINS2 -5683
RFC4 -5573
CCNE1 -5513
MAX -5422
CDK7 -5280
PSMA2 -5113
PSMD8 -5084
TFDP1 -5000
ORC2 -4586
PSMA1 -4584
POLD4 -4479
LIN9 -4346
STAG1 -4121
CDC27 -4048
RBX1 -4039
PSMB3 -4011
PSME4 -3807
GINS1 -3795
E2F1 -3673
ANAPC2 -3595
POLE -3565
ANAPC10 -3558
PSMB1 -3117
CUL1 -2987
ORC1 -2801
PSMA7 -2759
GSK3B -2656
PSMF1 -2512
AKT1 -2241
CDC6 -2240
CDC25B -2168
RPA1 -2002
ANAPC11 -1849
RFC5 -1846
PSMC1 -1839
PSMA6 -1800
CDCA5 -1650
CDKN1A -1607
E2F4 -1544
GINS4 -1375
CABLES1 -1276
DNA2 -1113
CCNA1 -948
PSMD1 -818
MCM6 -758
LIN37 -750
MYC -745
CDT1 -686
MCM2 -674
UBB -665
PSMA4 -648
ORC6 -370
ANAPC4 -298
RPS27A -126
POLE3 87
POLE2 373
ESCO1 490
MCM3 586
WEE1 588
GMNN 1002
PSMD11 1023
RPA3 1184
AKT3 1209
POLD1 1233
PSMB4 1285
PSMA5 1304
RBL2 1308
CDK4 1550
PSMC4 1596
SMC3 1750
RFC2 1966
PSME2 2084
RPA2 2309
CDC45 2313
MCM7 2427
MCM4 2571
UBE2D1 2677
PSMD12 2806
ANAPC1 2923
CCND1 3284
PSMD14 3679
PSMB6 4375
ORC5 5159
SEM1 5631
ANAPC15 6148
PSMD4 6169
UBA52 6282
PSMD5 6795
UBE2C 8787
PTK6 8932
PSMB11 9506


REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION

REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION
1163
set REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION
setSize 102
pANOVA 7.85e-11
s.dist -0.372
p.adjustANOVA 3.91e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
RRN3 -10966.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
H2AC20 -10208.0
POLR1E -10205.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
POLR1B -9824.0
MBD2 -9377.0
ERCC3 -9371.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
RRN3 -10966.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
H2AC20 -10208.0
POLR1E -10205.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
POLR1B -9824.0
MBD2 -9377.0
ERCC3 -9371.0
H2BC26 -9346.0
H2BC4 -9285.0
H2BC9 -9020.5
H3C7 -9020.5
TAF1B -8830.0
H2BC3 -8572.0
H4C3 -8451.0
GTF2H3 -8449.0
H2AC6 -8428.0
H2BC10 -8174.0
ERCC2 -7814.0
GTF2H1 -7675.0
MNAT1 -7673.0
H4C11 -7658.0
H2BC13 -7580.0
CCNH -7537.0
H3C1 -7492.0
H2BC5 -7339.0
KAT2B -7302.0
RBBP4 -7271.0
POLR1C -7120.0
MTA2 -7100.0
GATAD2B -7010.0
POLR2H -6881.0
TAF1D -6750.0
POLR1G -6552.0
H2BC1 -6434.0
POLR2L -5972.0
HDAC1 -5913.0
POLR2K -5634.0
H3-3B -5536.0
MBD3 -5490.0
H2BC8 -5414.0
H3C4 -5404.0
H3-3A -5377.0
CDK7 -5280.0
H2AC4 -4647.0
H3C8 -4535.0
HDAC2 -4377.0
H2BC11 -4063.0
H4C13 -3564.0
CHD3 -3438.0
MAPK3 -3089.0
POLR1H -2697.0
POLR1A -2555.0
H4C2 -2432.0
EHMT2 -2233.0
H2AZ2 -1872.0
CHD4 -1434.0
ERCC6 -1248.0
H2AC8 -1109.0
H2AJ -963.0
CBX3 -932.0
GTF2H5 -806.0
TBP -483.0
TAF1A -129.0
H4C12 -107.0
GTF2H4 183.0
POLR1D 218.0
H4C1 323.0
POLR2E 503.0
H4C8 685.0
H2BC17 842.0
H2AX 876.0
KAT2A 1331.0
UBTF 1426.0
H3C11 1739.0
POLR1F 1814.0
H3C10 2461.0
TAF1C 2477.0
H4C5 2528.0
GATAD2A 2784.0
POLR2F 3184.0
H3C2 3733.0
H4C4 4097.0
CAVIN1 4163.0
MTA1 4312.0
H2AZ1 4397.0
MTA3 4544.0
H4C16 4865.0
H4C6 5430.0
TTF1 7232.0


REACTOME_HCMV_LATE_EVENTS

REACTOME_HCMV_LATE_EVENTS
1466
set REACTOME_HCMV_LATE_EVENTS
setSize 110
pANOVA 8.83e-11
s.dist -0.358
p.adjustANOVA 4.27e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
H2AC12 -10676.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
H2AC15 -9502.0
H2BC26 -9346.0
NUP37 -9289.0
H2BC4 -9285.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
H2AC12 -10676.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
H2AC15 -9502.0
H2BC26 -9346.0
NUP37 -9289.0
H2BC4 -9285.0
H2BC9 -9020.5
H3C7 -9020.5
CHMP4B -9016.0
NUP50 -8870.0
H2AC13 -8863.0
VPS4A -8856.0
POM121 -8700.0
H2BC3 -8572.0
CHMP4C -8524.0
H4C3 -8451.0
H2AC6 -8428.0
NUP42 -8381.0
H2BC10 -8174.0
SEH1L -8137.0
NUP98 -8136.0
CHMP1A -8115.0
NUP107 -7996.0
H4C11 -7658.0
H2BC13 -7580.0
H3C1 -7492.0
H2AC21 -7400.0
CHMP6 -7353.0
H2BC5 -7339.0
HNRNPK -7107.0
NUP214 -6894.0
NUP160 -6475.0
SEC13 -6469.0
H2BC1 -6434.0
VPS37D -6348.0
H2AC25 -6343.0
RAE1 -6238.0
CHMP7 -5878.0
NUP155 -5740.0
VPS25 -5721.0
NUP88 -5526.0
H2BC8 -5414.0
H3C4 -5404.0
TSG101 -5215.0
VPS37C -4783.0
H2AC4 -4647.0
H3C8 -4535.0
NUP58 -4439.0
H2BC11 -4063.0
H2AC1 -3983.0
NUP188 -3926.0
H4C13 -3564.0
H2AC17 -3211.0
SNF8 -3150.0
VPS36 -3033.0
VPS37B -2493.0
H4C2 -2432.0
CHMP4A -2308.0
MVB12A -1668.0
AAAS -1523.0
TPR -1291.0
H2AC11 -1249.0
RANBP2 -1170.0
H2AC8 -1109.0
NUP153 -930.0
NUP93 -887.0
VPS28 -844.0
NDC1 -624.0
CHMP3 -318.0
H4C12 -107.0
H4C1 323.0
H2AC16 397.0
H4C8 685.0
H2BC17 842.0
NUP43 1180.0
UBAP1 1353.0
VPS37A 1354.0
CHMP2B 1663.0
H3C11 1739.0
NUP85 2430.0
H3C10 2461.0
H4C5 2528.0
NUP205 2803.0
NUP133 3158.0
NUP54 3235.0
NUP210 3259.0
H3C2 3733.0
H4C4 4097.0
NUP35 4792.0
H4C16 4865.0
MVB12B 5342.0
CHMP2A 5400.0
H4C6 5430.0
NUP62 5471.0
CEBPD 6510.0
POM121C 8315.0


REACTOME_MUSCLE_CONTRACTION

REACTOME_MUSCLE_CONTRACTION
674
set REACTOME_MUSCLE_CONTRACTION
setSize 197
pANOVA 1.08e-10
s.dist 0.267
p.adjustANOVA 5.06e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
MYL5 10625
MYH6 10582
DES 10519
MYL4 10455
ATP1A2 10367
TNNT3 10292
FXYD4 10199
MYL3 10134
CAMK2A 9899
KCNJ11 9821
FKBP1B 9729
TCAP 9687
PLN 9626
MYL7 9576
KCNK18 9551
TNNC2 9545
ACTG2 9472
KCNK7 9453
MYBPC3 9390
ACTN3 9262

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MYL5 10625
MYH6 10582
DES 10519
MYL4 10455
ATP1A2 10367
TNNT3 10292
FXYD4 10199
MYL3 10134
CAMK2A 9899
KCNJ11 9821
FKBP1B 9729
TCAP 9687
PLN 9626
MYL7 9576
KCNK18 9551
TNNC2 9545
ACTG2 9472
KCNK7 9453
MYBPC3 9390
ACTN3 9262
CAV3 9246
KCNJ12 9235
SCN5A 9135
KCNK16 9115
MYL2 9083
TRIM72 8968
FXYD6 8909
SCN4A 8819
KCNE2 8782
MYL10 8656
CACNA2D2 8600
SCN11A 8532
CORIN 8526
SCN4B 8520
ACTC1 8473
KCNIP3 8417
KCNA5 8402
TMOD1 8308
CACNA1G 8292
KCNJ4 8157
LMOD1 8053
NPR1 8017
ATP1B2 7966
ATP2B1 7902
CACNG6 7882
KCNK3 7737
SLC8A3 7667
CACNA1C 7608
CACNA1I 7602
TNNI1 7587
ATP1A4 7583
KCNIP1 7564
CACNG4 7523
SCN3A 7491
CASQ1 7359
DYSF 7326
ITGB5 7318
KCNK6 7285
RYR1 7251
CES1 7043
CAMK2B 7010
NPPC 7007
FXYD7 6944
GATA4 6866
KCNK4 6807
KCNK17 6766
KCNK5 6685
FXYD3 6525
TNNT2 6524
ATP2A3 6479
ATP2B2 6431
KCNK9 6294
FGF11 6293
FXYD2 6227
DMPK 6040
KCNK12 5988
ATP2A1 5933
WWTR1 5613
NKX2-5 5593
SORBS1 5321
SCN7A 5303
KCNE4 5287
MYH11 5196
MYBPC2 4989
TPM2 4971
ACTN2 4957
MYL9 4856
NOS1 4847
MYLK 4688
CACNG8 4413
SCN9A 4391
TNNI2 4357
MME 4026
KCNQ1 3992
TMOD4 3907
SLC8A2 3768
SCN2B 3749
KCND3 3553
ATP1A1 3477
TPM3 3434
ASPH 3322
SCN8A 3106
ATP2B4 3053
PAK1 2967
GUCY1A1 2951
ACTA1 2939
TMOD2 2895
CACNB2 2888
CACNG7 2860
NPR2 2828
PRKACA 2782
VIM 2512
TPM1 2267
TRPC1 2162
KCNH2 2161
RYR3 2130
SORBS3 1976
ATP1A3 1949
TNNC1 1937
HIPK1 1879
TMOD3 1849
SCN3B 1801
PDE5A 1667
ALDH2 1664
HIPK2 1642
CAMK2G 1409
CASQ2 1351
ANXA6 1034
KCNK10 808
MYL1 671
TBX5 314
KCNE3 297
SCN10A 38
CAMK2D 13
MYBPC1 -40
KCNK15 -135
FGF12 -347
SLN -426
CALD1 -577
ORAI2 -583
SCN2A -652
MYH8 -681
CALM1 -694
SCN1A -732
ATP1B1 -787
KCNIP2 -816
ABCC9 -1045
NEB -1116
PXN -1184
ITPR3 -1366
TLN1 -1694
MYL12B -1777
ORAI1 -2155
KCND2 -2293
ATP1B3 -2350
SLC8A1 -2552
CACNB1 -2620
MYL11 -2853
ITGA1 -3003
AHCYL1 -3022
RYR2 -3495
GUCY1A2 -3942
PAK2 -3995
KCNJ2 -4066
CACNA1H -4144
KCNK13 -4205
MYL6B -4385
ANXA1 -4452
ACTA2 -4892
KCNE1 -4924
SCN1B -5266
FGF14 -5690
KCNK2 -5896
ATP2A2 -6154
SRI -6394
NPPA -6636
AKAP9 -6655
KCNJ14 -6875
MYL6 -6909
ITPR2 -7172
ANXA2 -7286
KAT2B -7302
KCNIP4 -7415
TTN -7480
ITPR1 -7781
KCNK1 -7804
STIM1 -8016
VCL -8740
MYH3 -8982
MYL12A -9202
RANGRF -9477
TNNT1 -9980
TPM4 -10203
TRDN -10295
GUCY1B1 -10406
TNNI3 -10715
FXYD1 -10889


REACTOME_MITOTIC_PROPHASE

REACTOME_MITOTIC_PROPHASE
1093
set REACTOME_MITOTIC_PROPHASE
setSize 134
pANOVA 1.23e-10
s.dist -0.322
p.adjustANOVA 5.61e-09



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
ENSA -10263.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
RB1 -10080.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
SET -10005.0
CTDNEP1 -9802.0
NCAPH2 -9726.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
ENSA -10263.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
RB1 -10080.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
SET -10005.0
CTDNEP1 -9802.0
NCAPH2 -9726.0
CCNB2 -9510.0
H2BC26 -9346.0
NUP37 -9289.0
H2BC4 -9285.0
BLZF1 -9154.0
H2BC9 -9020.5
H3C7 -9020.5
NUP50 -8870.0
RAB2A -8861.0
VRK2 -8725.0
POM121 -8700.0
RAB1B -8678.0
H2BC3 -8572.0
H4C3 -8451.0
H2AC6 -8428.0
NUP42 -8381.0
GOLGA2 -8279.0
H2BC10 -8174.0
GORASP2 -8167.0
SEH1L -8137.0
NUP98 -8136.0
KMT5A -8065.0
NUP107 -7996.0
RAB1A -7794.0
H4C11 -7658.0
H2BC13 -7580.0
LEMD3 -7493.0
H3C1 -7492.0
H2BC5 -7339.0
NUP214 -6894.0
NUP160 -6475.0
SEC13 -6469.0
H2BC1 -6434.0
RAE1 -6238.0
LMNB1 -6160.0
GORASP1 -6022.0
NUP155 -5740.0
NEK7 -5636.0
H3-3B -5536.0
NUP88 -5526.0
H2BC8 -5414.0
H3C4 -5404.0
H3-3A -5377.0
VRK1 -5349.0
PPP2R2D -5129.0
BANF1 -5058.0
NCAPG2 -4857.0
H2AC4 -4647.0
H3C8 -4535.0
NUP58 -4439.0
SMC2 -4271.0
H2BC11 -4063.0
NUP188 -3926.0
PPP2R1B -3830.0
SMC4 -3591.0
H4C13 -3564.0
CNEP1R1 -3416.0
MAPK1 -3156.0
MAPK3 -3089.0
USO1 -3012.0
MASTL -2711.0
H4C2 -2432.0
MCPH1 -2360.0
LPIN1 -2351.0
PPP2R1A -2279.0
H2AZ2 -1872.0
AAAS -1523.0
TPR -1291.0
RANBP2 -1170.0
NEK9 -1121.0
H2AC8 -1109.0
NUMA1 -1031.0
H2AJ -963.0
NUP153 -930.0
NUP93 -887.0
PLK1 -706.0
NDC1 -624.0
PPP2CB -279.0
H4C12 -107.0
PPP2CA -76.0
PRKCB 3.0
H4C1 323.0
NCAPD3 500.0
H4C8 685.0
PRKCA 781.0
H2BC17 842.0
H2AX 876.0
NUP43 1180.0
LEMD2 1581.0
H3C11 1739.0
ARPP19 2091.0
NUP85 2430.0
H3C10 2461.0
H4C5 2528.0
TMPO 2666.0
NUP205 2803.0
NUP133 3158.0
NUP54 3235.0
NUP210 3259.0
LPIN2 3323.0
H3C2 3733.0
H4C4 4097.0
CCNB1 4274.0
H2AZ1 4397.0
NUP35 4792.0
H4C16 4865.0
CDK1 4923.0
H4C6 5430.0
NUP62 5471.0
LPIN3 6687.0
H3-4 7087.0
LMNA 7850.0
POM121C 8315.0
NEK6 8708.0


REACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE

REACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE
501
set REACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE
setSize 118
pANOVA 4.17e-10
s.dist -0.333
p.adjustANOVA 1.85e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
MIR24-2 -10766.0
H2AC14 -10727.0
TXN -10530.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
MOV10 -10287.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
CDK6 -9698.0
MAPK14 -9643.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
MIR24-2 -10766.0
H2AC14 -10727.0
TXN -10530.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
MOV10 -10287.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
CDK6 -9698.0
MAPK14 -9643.0
MAP2K6 -9611.0
H2BC26 -9346.0
H2BC4 -9285.0
H2BC9 -9020.5
H3C7 -9020.5
BMI1 -8777.0
CDKN2C -8656.0
SUZ12 -8594.0
H2BC3 -8572.0
H4C3 -8451.0
H2AC6 -8428.0
MIR24-1 -8349.0
UBC -8277.0
H2BC10 -8174.0
KDM6B -8060.0
TNRC6B -7724.0
H4C11 -7658.0
H2BC13 -7580.0
AGO4 -7579.0
H3C1 -7492.0
H2BC5 -7339.0
RBBP4 -7271.0
MAPKAPK5 -7178.0
TFDP2 -7095.0
CBX8 -6705.0
H2BC1 -6434.0
MAP3K5 -6350.0
IFNB1 -5863.0
CDKN2A -5841.0
H3-3B -5536.0
H2BC8 -5414.0
H3C4 -5404.0
H3-3A -5377.0
E2F3 -5327.0
TNIK -5126.0
CBX6 -5107.0
TFDP1 -5000.0
RNF2 -4904.0
H2AC4 -4647.0
H3C8 -4535.0
MAPKAPK3 -4102.0
H2BC11 -4063.0
CBX4 -3688.0
E2F1 -3673.0
H4C13 -3564.0
MAPK1 -3156.0
MAPK3 -3089.0
AGO3 -3073.0
PHC2 -3014.0
JUN -2945.0
EED -2898.0
MDM4 -2718.0
EZH2 -2496.0
H4C2 -2432.0
MAP4K4 -2334.0
H2AZ2 -1872.0
MAPK10 -1331.0
MAPKAPK2 -1227.0
H2AC8 -1109.0
H2AJ -963.0
E2F2 -920.0
FOS -894.0
CBX2 -849.0
RING1 -740.0
UBB -665.0
MAP2K4 -452.0
TNRC6A -436.0
MAPK9 -429.0
SCMH1 -327.0
RPS27A -126.0
H4C12 -107.0
MDM2 136.0
H4C1 323.0
AGO1 376.0
MINK1 600.0
H4C8 685.0
H2BC17 842.0
H2AX 876.0
CDK4 1550.0
PHC3 1727.0
H3C11 1739.0
H3C10 2461.0
H4C5 2528.0
MAP2K3 2764.0
TNRC6C 3185.0
MAPK8 3528.0
H3C2 3733.0
MAP2K7 3747.0
CDKN2B 4021.0
H4C4 4097.0
H2AZ1 4397.0
MAPK11 4578.0
H4C16 4865.0
H4C6 5430.0
TP53 5757.0
PHC1 6131.0
UBA52 6282.0
CDKN2D 9657.0


REACTOME_HCMV_INFECTION

REACTOME_HCMV_INFECTION
1463
set REACTOME_HCMV_INFECTION
setSize 152
pANOVA 7.74e-10
s.dist -0.289
p.adjustANOVA 3.35e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
H2AC12 -10676.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
TUBA1A -9776.0
TUBA3E -9762.0
H2AC15 -9502.0
H2BC26 -9346.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
H2AC12 -10676.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
TUBA1A -9776.0
TUBA3E -9762.0
H2AC15 -9502.0
H2BC26 -9346.0
NUP37 -9289.0
H2BC4 -9285.0
GPS2 -9206.0
H2BC9 -9020.5
H3C7 -9020.5
CHMP4B -9016.0
DYNLL1 -8928.0
TUBA3C -8877.0
NUP50 -8870.0
H2AC13 -8863.0
VPS4A -8856.0
POM121 -8700.0
SUZ12 -8594.0
H2BC3 -8572.0
CHMP4C -8524.0
H4C3 -8451.0
H2AC6 -8428.0
NUP42 -8381.0
H2BC10 -8174.0
SEH1L -8137.0
NUP98 -8136.0
CHMP1A -8115.0
NUP107 -7996.0
H4C11 -7658.0
H2BC13 -7580.0
H3C1 -7492.0
H2AC21 -7400.0
CHMP6 -7353.0
H2BC5 -7339.0
RBBP4 -7271.0
TUBA1B -7184.0
HNRNPK -7107.0
DYNC1LI1 -7041.0
NUP214 -6894.0
TUBA1C -6503.0
NUP160 -6475.0
SEC13 -6469.0
H2BC1 -6434.0
VPS37D -6348.0
H2AC25 -6343.0
RAE1 -6238.0
DYNC1LI2 -6196.0
CBX1 -6145.0
NCOR2 -6078.0
TUBAL3 -5968.0
CHMP7 -5878.0
NUP155 -5740.0
VPS25 -5721.0
NUP88 -5526.0
PML -5486.0
H2BC8 -5414.0
H3C4 -5404.0
TSG101 -5215.0
DYNC1H1 -5010.0
VPS37C -4783.0
DYNC1I2 -4740.0
H2AC4 -4647.0
ITGB1 -4570.0
H3C8 -4535.0
NUP58 -4439.0
TBL1XR1 -4414.0
H2BC11 -4063.0
H2AC1 -3983.0
NUP188 -3926.0
H4C13 -3564.0
H2AC17 -3211.0
SNF8 -3150.0
VPS36 -3033.0
EED -2898.0
HDAC3 -2723.0
EZH2 -2496.0
VPS37B -2493.0
H4C2 -2432.0
CHMP4A -2308.0
CREB1 -2161.0
MVB12A -1668.0
AAAS -1523.0
TPR -1291.0
H2AC11 -1249.0
RANBP2 -1170.0
TUBB4B -1137.0
H2AC8 -1109.0
NUP153 -930.0
NUP93 -887.0
VPS28 -844.0
NDC1 -624.0
NFKB1 -487.0
CHMP3 -318.0
DYNC1I1 -230.0
H4C12 -107.0
TUBB2A 305.0
H4C1 323.0
H2AC16 397.0
H4C8 685.0
H2BC17 842.0
NUP43 1180.0
UBAP1 1353.0
VPS37A 1354.0
DAXX 1573.0
CHMP2B 1663.0
H3C11 1739.0
NUP85 2430.0
H3C10 2461.0
H4C5 2528.0
TUBA3D 2717.0
NUP205 2803.0
NUP133 3158.0
NUP54 3235.0
NUP210 3259.0
TUBB6 3395.0
EGFR 3462.0
H3C2 3733.0
NCOR1 3766.0
TRIM28 4029.0
H4C4 4097.0
NUP35 4792.0
H4C16 4865.0
TUBB1 5090.0
MVB12B 5342.0
CHMP2A 5400.0
H4C6 5430.0
NUP62 5471.0
DYNLL2 5999.0
TUBA4B 6042.0
TUBB4A 6369.0
CEBPD 6510.0
TUBA4A 6664.0
TUBB3 6928.0
TUBB2B 7929.0
TUBA8 8140.0
POM121C 8315.0
TUBB8 9559.0


REACTOME_PRC2_METHYLATES_HISTONES_AND_DNA

REACTOME_PRC2_METHYLATES_HISTONES_AND_DNA
440
set REACTOME_PRC2_METHYLATES_HISTONES_AND_DNA
setSize 65
pANOVA 8.49e-10
s.dist -0.44
p.adjustANOVA 3.58e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
JARID2 -9908.0
H2BC26 -9346.0
H2BC4 -9285.0
H2BC9 -9020.5
H3C7 -9020.5

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
JARID2 -9908.0
H2BC26 -9346.0
H2BC4 -9285.0
H2BC9 -9020.5
H3C7 -9020.5
AEBP2 -8793.0
SUZ12 -8594.0
H2BC3 -8572.0
H4C3 -8451.0
H2AC6 -8428.0
H2BC10 -8174.0
H4C11 -7658.0
H2BC13 -7580.0
H3C1 -7492.0
H2BC5 -7339.0
RBBP4 -7271.0
MTF2 -6719.0
DNMT1 -6562.0
DNMT3B -6553.0
H2BC1 -6434.0
PHF1 -5862.0
H3-3B -5536.0
H2BC8 -5414.0
H3C4 -5404.0
H3-3A -5377.0
H2AC4 -4647.0
H3C8 -4535.0
H2BC11 -4063.0
H4C13 -3564.0
EED -2898.0
EZH2 -2496.0
H4C2 -2432.0
H2AZ2 -1872.0
H2AC8 -1109.0
H2AJ -963.0
H4C12 -107.0
H4C1 323.0
H4C8 685.0
H2BC17 842.0
H2AX 876.0
H3C11 1739.0
H3C10 2461.0
H4C5 2528.0
DNMT3A 3442.0
H3C2 3733.0
H4C4 4097.0
H2AZ1 4397.0
PHF19 4821.0
H4C16 4865.0
H4C6 5430.0


REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS

REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS
901
set REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS
setSize 113
pANOVA 1.27e-09
s.dist -0.33
p.adjustANOVA 5.22e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
HOXB2 -11067.0
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
ASH2L -10434.0
H2BC6 -10375.0
MEIS1 -10367.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
EP300 -9652.0
YY1 -9573.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
HOXB2 -11067.0
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
ASH2L -10434.0
H2BC6 -10375.0
MEIS1 -10367.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
EP300 -9652.0
YY1 -9573.0
H2BC26 -9346.0
H2BC4 -9285.0
H2BC9 -9020.5
H3C7 -9020.5
KMT2C -8999.0
HOXB4 -8785.0
PAXIP1 -8605.0
SUZ12 -8594.0
H2BC3 -8572.0
H4C3 -8451.0
H2AC6 -8428.0
H2BC10 -8174.0
PAGR1 -7857.0
H4C11 -7658.0
H2BC13 -7580.0
H3C1 -7492.0
H2BC5 -7339.0
CNOT6 -7337.0
RBBP4 -7271.0
POLR2H -6881.0
PCGF2 -6508.0
H2BC1 -6434.0
MAFB -5976.0
POLR2L -5972.0
POLR2K -5634.0
H3-3B -5536.0
HOXB3 -5487.0
H2BC8 -5414.0
H3C4 -5404.0
H3-3A -5377.0
PIAS2 -4881.0
H2AC4 -4647.0
H3C8 -4535.0
CNOT9 -4525.0
HOXA4 -4134.0
H2BC11 -4063.0
WDR5 -4056.0
POLR2G -3937.0
ZNF335 -3874.0
POLR2B -3768.0
HOXD4 -3650.0
H4C13 -3564.0
CTCF -3487.0
HOXA1 -3007.0
RARG -2993.0
JUN -2945.0
EED -2898.0
NCOA3 -2868.0
HDAC3 -2723.0
EZH2 -2496.0
H4C2 -2432.0
NCOA6 -2407.0
RBBP5 -2037.0
H2AZ2 -1872.0
RARA -1743.0
POLR2I -1736.0
CREBBP -1603.0
POLR2A -1290.0
H2AC8 -1109.0
H2AJ -963.0
PKNOX1 -846.0
EGR2 -667.0
RARB -472.0
H4C12 -107.0
HOXD1 7.0
PBX1 194.0
POLR2C 198.0
KMT2D 302.0
H4C1 323.0
POLR2E 503.0
H4C8 685.0
RXRA 721.0
H2BC17 842.0
H2AX 876.0
H3C11 1739.0
HOXD3 1815.0
POLR2D 2370.0
H3C10 2461.0
H4C5 2528.0
PAX6 2691.0
AJUBA 2746.0
POLR2F 3184.0
POLR2J 3674.0
H3C2 3733.0
NCOR1 3766.0
H4C4 4097.0
H2AZ1 4397.0
H4C16 4865.0
HOXB1 5330.0
H4C6 5430.0
HOXA3 5983.0
HOXC4 6014.0
HOXA2 7244.0


REACTOME_RHO_GTPASE_EFFECTORS

REACTOME_RHO_GTPASE_EFFECTORS
342
set REACTOME_RHO_GTPASE_EFFECTORS
setSize 305
pANOVA 1.36e-09
s.dist -0.202
p.adjustANOVA 5.43e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
LIMK1 -10831.0
H3C3 -10808.0
H2AC14 -10727.0
PIK3R4 -10693.0
S100A8 -10452.0
LIN7B -10411.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
DSN1 -10243.0
KIF2B -10210.0
H2AC20 -10208.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
LIMK1 -10831.0
H3C3 -10808.0
H2AC14 -10727.0
PIK3R4 -10693.0
S100A8 -10452.0
LIN7B -10411.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
DSN1 -10243.0
KIF2B -10210.0
H2AC20 -10208.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
TUBA1A -9776.0
TUBA3E -9762.0
PIK3C3 -9658.0
MAPK14 -9643.0
CDC42 -9607.0
GOPC -9601.0
PMF1 -9524.0
PIN1 -9485.0
KLC1 -9469.0
ROCK2 -9424.0
KIF18A -9410.0
CLASP2 -9395.0
H2BC26 -9346.0
NUP37 -9289.0
H2BC4 -9285.0
YWHAZ -9228.0
NF2 -9215.0
NCK1 -9181.0
PRC1 -9088.0
H2BC9 -9020.5
H3C7 -9020.5
CENPM -8958.0
SRF -8938.0
NCKAP1L -8929.0
DYNLL1 -8928.0
TUBA3C -8877.0
ABI2 -8825.0
KIF14 -8703.0
CENPH -8650.0
SGO2 -8632.0
NCOA2 -8586.0
H2BC3 -8572.0
CENPT -8464.0
H4C3 -8451.0
KIF2C -8448.0
H2AC6 -8428.0
SCAI -8424.0
BUB1B -8413.0
NDE1 -8382.0
MAPRE1 -8365.0
IQGAP3 -8290.0
PKN2 -8243.0
H2BC10 -8174.0
SEH1L -8137.0
NUP98 -8136.0
NUP107 -7996.0
DIAPH3 -7795.0
DVL1 -7768.0
H4C11 -7658.0
NCKAP1 -7622.0
CDCA8 -7604.0
H2BC13 -7580.0
H3C1 -7492.0
ROCK1 -7387.0
H2BC5 -7339.0
YWHAG -7293.0
CDC25C -7260.0
CENPQ -7210.0
TUBA1B -7184.0
KDM1A -7160.0
NUDC -7128.0
KDM4C -7122.0
DYNC1LI1 -7041.0
IQGAP2 -6976.0
MYL6 -6909.0
WASF2 -6781.0
PPP1CB -6679.0
SPC25 -6632.0
TUBA1C -6503.0
NUP160 -6475.0
SEC13 -6469.0
MRTFA -6462.0
NDEL1 -6443.0
H2BC1 -6434.0
CDKN1B -6381.0
NOXA1 -6365.0
CLIP1 -6364.0
ACTR2 -6324.0
KLC2 -6315.0
PAFAH1B1 -6282.0
DYNC1LI2 -6196.0
PPP1R12B -6165.0
KNTC1 -6122.0
TUBAL3 -5968.0
RAC1 -5965.0
PFN2 -5885.0
ZWILCH -5742.0
MIS12 -5727.0
GRB2 -5691.0
KNL1 -5659.0
KTN1 -5587.0
ABL1 -5559.0
H3-3B -5536.0
H2BC8 -5414.0
H3C4 -5404.0
WIPF2 -5398.0
H3-3A -5377.0
RANGAP1 -5347.0
PPP2R5A -5281.0
ZW10 -5219.0
BUB1 -5121.0
LIMK2 -5025.0
DYNC1H1 -5010.0
NSL1 -4893.0
DYNC1I2 -4740.0
CENPE -4657.0
H2AC4 -4647.0
CENPF -4587.0
DIAPH1 -4579.0
ITGB1 -4570.0
PDPK1 -4559.0
H3C8 -4535.0
CENPA -4213.0
TAX1BP3 -4196.0
ARPC1A -4158.0
RHOQ -4088.0
H2BC11 -4063.0
INCENP -4030.0
PAK2 -3995.0
SKA2 -3991.0
PPP2R1B -3830.0
ACTR3 -3798.0
ARPC3 -3699.0
PPP2R5E -3697.0
H4C13 -3564.0
KIF2A -3457.0
XPO1 -3414.0
ARPC4 -3392.0
NCF4 -3338.0
MAPK1 -3156.0
MAPK3 -3089.0
CIT -2873.0
MAD1L1 -2784.0
CKAP5 -2548.0
WASL -2457.0
H4C2 -2432.0
WASF1 -2304.0
PPP2R1A -2279.0
KLK3 -2132.0
KIF5B -2072.0
ITGB3BP -1875.0
H2AZ2 -1872.0
MYL12B -1777.0
NUF2 -1758.0
B9D2 -1720.0
ACTG1 -1669.0
CENPO -1579.0
RHOA -1526.0
AHCTF1 -1446.0
SPDL1 -1326.0
MYH10 -1302.0
CENPC -1213.0
RANBP2 -1170.0
TUBB4B -1137.0
H2AC8 -1109.0
H2AJ -963.0
YWHAE -811.0
PRKCD -789.0
DAAM1 -755.0
NDC80 -719.0
PLK1 -706.0
CALM1 -694.0
SPC24 -642.0
PPP2R5C -627.0
RHOB -613.0
PPP1R12A -597.0
EVL -321.0
DVL3 -317.0
CENPN -295.0
PPP2CB -279.0
DYNC1I1 -230.0
H4C12 -107.0
ARPC5 -95.0
PPP2CA -76.0
PRKCB 3.0
CLASP1 37.0
AURKB 55.0
CENPP 177.0
PTK2 209.0
ARPC2 246.0
TUBB2A 305.0
H4C1 323.0
PFN1 436.0
RHOG 493.0
PPP2R5D 498.0
CYBA 541.0
SRGAP2 551.0
SKA1 603.0
YWHAB 626.0
CTNNB1 682.0
H4C8 685.0
NOX3 729.0
IQGAP1 765.0
PRKCA 781.0
H2BC17 842.0
H2AX 876.0
CENPL 945.0
CTNNA1 1007.0
NUP43 1180.0
DVL2 1256.0
TAOK1 1373.0
PPP1R14A 1390.0
MAD2L1 1519.0
RHPN1 1559.0
ZWINT 1577.0
YWHAH 1579.0
CENPS 1636.0
NCKIPSD 1736.0
H3C11 1739.0
CYFIP2 1788.0
CENPK 1845.0
S100A9 1916.0
BRK1 1967.0
MYH14 2075.0
ABI1 2119.0
RPS27 2171.0
BUB3 2174.0
BIRC5 2299.0
NUP85 2430.0
H3C10 2461.0
H4C5 2528.0
TUBA3D 2717.0
CFL1 2727.0
DLG4 2821.0
CYFIP1 2859.0
PAK1 2967.0
YWHAQ 3040.0
WIPF1 3085.0
ACTB 3141.0
NUP133 3158.0
RHOC 3214.0
PPP2R5B 3218.0
MYH9 3240.0
MEN1 3390.0
TUBB6 3395.0
CDC20 3609.0
H3C2 3733.0
ARPC1B 3767.0
PRKCZ 3786.0
H4C4 4097.0
NCF2 4142.0
H2AZ1 4397.0
SGO1 4410.0
RCC2 4422.0
CFTR 4482.0
MAPK11 4578.0
MYLK 4688.0
PPP1CC 4750.0
WASF3 4820.0
MYL9 4856.0
H4C16 4865.0
CENPU 5042.0
TUBB1 5090.0
FMNL1 5119.0
MYH11 5196.0
RAC2 5363.0
H4C6 5430.0
CTTN 5472.0
DYNLL2 5999.0
TUBA4B 6042.0
KLC4 6165.0
KLK2 6180.0
TUBB4A 6369.0
NOXO1 6429.0
FMNL2 6575.0
FMNL3 6585.0
PKN1 6630.0
BAIAP2 6655.0
TUBA4A 6664.0
KLC3 6848.0
PKN3 6873.0
TUBB3 6928.0
CDH1 7228.0
RHPN2 7277.0
WIPF3 7773.0
SRC 7873.0
TUBB2B 7929.0
TUBA8 8140.0
KIF5A 9306.0
RTKN 9395.0
TUBB8 9559.0
RHOD 9809.0
SFN 10291.0
ROPN1 10655.0


REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE

REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE
500
set REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE
setSize 228
pANOVA 1.77e-09
s.dist -0.231
p.adjustANOVA 6.89e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
PSMB7 -10651
PSMC6 -10621
DSN1 -10243
KIF2B -10210
PSMD2 -10209
PSMC2 -10087
PSMA3 -9831
TUBA1A -9776
RAD21 -9775
TUBA3E -9762
PSMB8 -9616
PMF1 -9524
CCNB2 -9510
PSME1 -9420
KIF18A -9410
CLASP2 -9395
TNPO1 -9369
PSMC5 -9310
NUP37 -9289
ANAPC16 -9057

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PSMB7 -10651
PSMC6 -10621
DSN1 -10243
KIF2B -10210
PSMD2 -10209
PSMC2 -10087
PSMA3 -9831
TUBA1A -9776
RAD21 -9775
TUBA3E -9762
PSMB8 -9616
PMF1 -9524
CCNB2 -9510
PSME1 -9420
KIF18A -9410
CLASP2 -9395
TNPO1 -9369
PSMC5 -9310
NUP37 -9289
ANAPC16 -9057
PSMA8 -9037
CHMP4B -9016
CENPM -8958
KPNB1 -8945
DYNLL1 -8928
TUBA3C -8877
VPS4A -8856
CDC23 -8726
VRK2 -8725
POM121 -8700
CENPH -8650
PSME3 -8645
SGO2 -8632
CHMP4C -8524
PSMD3 -8488
CENPT -8464
KIF2C -8448
BUB1B -8413
NDE1 -8382
MAPRE1 -8365
UBC -8277
SEH1L -8137
NUP98 -8136
ANAPC7 -8113
PSMD6 -8047
NUP107 -7996
CDCA8 -7604
PSMB10 -7549
LEMD3 -7493
PSMD7 -7470
CDC16 -7384
PSMB5 -7376
CHMP6 -7353
CDC26 -7245
CENPQ -7210
SUMO1 -7196
TUBA1B -7184
NUDC -7128
DYNC1LI1 -7041
PSMB2 -7000
PSMB9 -6985
PSMD9 -6972
PDS5B -6842
SPC25 -6632
TUBA1C -6503
PDS5A -6492
NUP160 -6475
SEC13 -6469
NDEL1 -6443
CLIP1 -6364
CC2D1B -6346
ANAPC5 -6314
PAFAH1B1 -6282
DYNC1LI2 -6196
LMNB1 -6160
UBE2E1 -6123
KNTC1 -6122
WAPL -6116
PSMC3 -6093
TUBAL3 -5968
PSMD13 -5903
CHMP7 -5878
UBE2S -5833
ZWILCH -5742
NUP155 -5740
MIS12 -5727
KNL1 -5659
VRK1 -5349
RANGAP1 -5347
PPP2R5A -5281
ZW10 -5219
BUB1 -5121
PSMA2 -5113
PSMD8 -5084
BANF1 -5058
DYNC1H1 -5010
NSL1 -4893
DYNC1I2 -4740
CENPE -4657
CENPF -4587
PSMA1 -4584
NUP58 -4439
RAN -4434
IST1 -4390
PTTG1 -4379
CENPA -4213
STAG1 -4121
CDC27 -4048
INCENP -4030
PSMB3 -4011
SKA2 -3991
NUP188 -3926
PPP2R1B -3830
PSME4 -3807
ESPL1 -3747
PPP2R5E -3697
ANAPC2 -3595
ANAPC10 -3558
KIF2A -3457
XPO1 -3414
RCC1 -3204
PSMB1 -3117
MAD1L1 -2784
PSMA7 -2759
SPAST -2591
CKAP5 -2548
PSMF1 -2512
CHMP4A -2308
PPP2R1A -2279
ITGB3BP -1875
ANAPC11 -1849
PSMC1 -1839
PSMA6 -1800
NUF2 -1758
B9D2 -1720
CDCA5 -1650
CENPO -1579
AHCTF1 -1446
SPDL1 -1326
CENPC -1213
RANBP2 -1170
TUBB4B -1137
LBR -1114
NUP93 -887
FBXO5 -853
PSMD1 -818
NDC80 -719
PLK1 -706
UBB -665
PSMA4 -648
SPC24 -642
PPP2R5C -627
NDC1 -624
CHMP3 -318
ANAPC4 -298
CENPN -295
PPP2CB -279
DYNC1I1 -230
RPS27A -126
PPP2CA -76
CLASP1 37
AURKB 55
PPP2R2A 137
CENPP 177
TUBB2A 305
PPP2R5D 498
UBE2I 578
SKA1 603
CENPL 945
PSMD11 1023
NUP43 1180
SIRT2 1269
PSMB4 1285
PSMA5 1304
TAOK1 1373
MAD2L1 1519
ZWINT 1577
LEMD2 1581
PSMC4 1596
CENPS 1636
CHMP2B 1663
SMC3 1750
CENPK 1845
PSME2 2084
RPS27 2171
BUB3 2174
BIRC5 2299
NUP85 2430
TMPO 2666
UBE2D1 2677
TUBA3D 2717
NUP205 2803
PSMD12 2806
ANAPC1 2923
NUP133 3158
PPP2R5B 3218
NUP54 3235
TUBB6 3395
CDC20 3609
PSMD14 3679
ANKLE2 3712
CCNB1 4274
PSMB6 4375
SGO1 4410
RCC2 4422
PPP1CC 4750
NUP35 4792
CDK1 4923
CENPU 5042
TUBB1 5090
CHMP2A 5400
NUP62 5471
SEM1 5631
DYNLL2 5999
TUBA4B 6042
ANAPC15 6148
PSMD4 6169
UBA52 6282
TUBB4A 6369
TUBA4A 6664
PSMD5 6795
TUBB3 6928
LMNA 7850
TUBB2B 7929
TUBA8 8140
UBE2C 8787
PSMB11 9506
TUBB8 9559


REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS
594
set REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS
setSize 312
pANOVA 1.8e-09
s.dist 0.198
p.adjustANOVA 6.89e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
MLN 10633
TAC3 10566
LPAR5 10498
CHRM4 10490
CCL22 10472
CCL19 10427
CCL13 10381
MLNR 10345
CCL5 10328
PROKR1 10320
PPY 10304
GALR3 10243
CCL27 10220
NPW 10146
HCRTR1 10123
INSL5 10093
PROK1 10059
CCR3 10028
CCL17 9933
CCL16 9860

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MLN 10633
TAC3 10566
LPAR5 10498
CHRM4 10490
CCL22 10472
CCL19 10427
CCL13 10381
MLNR 10345
CCL5 10328
PROKR1 10320
PPY 10304
GALR3 10243
CCL27 10220
NPW 10146
HCRTR1 10123
INSL5 10093
PROK1 10059
CCR3 10028
CCL17 9933
CCL16 9860
GPR37L1 9855
CXCR2 9804
CCL20 9802
GPR31 9705
HCAR1 9676
PPBP 9636
UTS2R 9612
HTR4 9590
ADORA1 9584
LPAR1 9544
ADRA1D 9502
TACR2 9481
P2RY6 9474
CX3CL1 9438
GPR55 9434
GPR4 9432
ADORA2A 9421
PRLH 9415
RLN3 9370
ACKR2 9333
CHRM1 9309
KEL 9303
CCL11 9274
CXCL9 9241
MCHR1 9232
XCL1 9205
C5AR2 9180
CCR2 9141
POMC 9122
CORT 9076
FFAR4 8900
PTAFR 8896
CCR9 8857
UTS2 8803
ADRB2 8786
CXCR1 8715
FFAR1 8694
GNRH2 8686
TAAR1 8667
CCR6 8634
HTR1D 8622
CCRL2 8523
CXCR5 8494
CCL2 8464
CCL1 8429
CX3CR1 8393
QRFP 8344
PTGIR 8327
NPY2R 8307
MC1R 8260
PYY 8254
NPFFR1 8139
OXER1 8118
ACKR4 8111
CCKAR 8039
NMUR1 7976
CMKLR1 7904
C3AR1 7878
NPY 7862
HRH1 7820
AGT 7651
CXCL16 7609
CXCL5 7515
NTSR1 7446
GPR39 7384
RHO 7351
KISS1 7299
DRD2 7269
OPN3 7200
CCL7 7186
S1PR3 7183
NPBWR2 7174
GPR132 7143
AGTR1 7090
PLPPR3 7070
RLN2 7058
TAC1 7056
P2RY2 7022
PDYN 6987
AVP 6951
GPR183 6794
TACR1 6709
EDNRB 6681
RXFP4 6648
XCR1 6621
F2 6618
UTS2B 6611
TRHR 6603
PLPPR2 6562
CXCL12 6390
DRD4 6240
CCR5 6200
CGA 6197
MC5R 6125
KNG1 6104
LPAR3 6066
SSTR4 6055
C3 5919
ECE2 5899
CXCL2 5815
GPR68 5731
GPR17 5695
TAAR5 5686
FSHR 5546
BDKRB1 5480
GPR35 5277
HTR1E 5261
FFAR3 5243
GALR2 4839
GALR1 4770
PNOC 4689
BDKRB2 4679
OPRL1 4656
PSAP 4611
MC3R 4559
NPY1R 4439
HTR1F 4430
RXFP1 4321
GPER1 4314
CCR10 4310
CCK 4301
CXCL1 4149
KISS1R 4131
CCL28 4119
TAAR9 4047
PTGDR 3939
NPB 3833
F2R 3760
OPRD1 3682
DRD5 3605
P2RY11 3601
NMU 3560
CXCL13 3454
CNR2 3402
P2RY12 3278
NPY5R 3097
LPAR2 2993
F2RL1 2813
NMB 2741
NPBWR1 2709
CCL3 2612
ADRA1B 2520
ADRB1 2501
NTS 2442
RGR 2181
PF4 2093
NTSR2 1837
ACKR1 1835
CHRM2 1826
GNRH1 1735
PTGER1 1586
INSL3 1447
GAL 1395
EDN3 1384
PTGER4 1291
CCR7 1236
EDN1 1227
ADRA2A 1181
ADRA2B 1141
CHRM3 1114
SSTR1 1013
MC2R 1001
EDNRA 943
CCL21 902
TSHR 707
OPN1SW 689
OXGR1 633
HCRT 328
SSTR2 327
CCL23 230
OXTR 208
P2RY14 182
C5AR1 -26
HCAR2 -62
APLNR -178
PTGFR -308
HTR6 -421
PLPPR5 -565
OPN5 -578
TBXA2R -618
S1PR1 -631
HRH2 -737
GPR65 -821
HTR2A -829
ECE1 -859
EDN2 -945
OPRM1 -1005
NLN -1281
S1PR4 -1318
S1PR5 -1411
HTR2B -1494
TAAR6 -1575
ADRA2C -1621
P2RY13 -1660
CXCR4 -1674
HTR5A -1989
LTB4R -2130
PMCH -2149
GNRHR -2176
C5 -2310
CXCR6 -2426
RXFP2 -2699
CCKBR -2902
AVPR1A -3043
HRH3 -3056
CNR1 -3288
NMS -3349
ADRB3 -3367
MTNR1B -3446
CXCL3 -3451
FPR3 -3459
ADORA3 -3509
GPR37 -3635
CHRM5 -3841
TRH -3869
CXCL11 -3898
LHCGR -3915
ADRA1A -4065
QRFPR -4101
GPHB5 -4119
SUCNR1 -4133
PLPPR4 -4143
HEBP1 -4246
PENK -4279
DRD1 -4293
CCR4 -4444
ANXA1 -4452
PLPPR1 -4539
RXFP3 -4651
PROK2 -4868
GHSR -4922
S1PR2 -5023
APP -5218
AVPR1B -5243
NMUR2 -5317
SST -5379
FPR2 -5517
GPBAR1 -5538
DRD3 -5541
NPFFR2 -5562
HTR7 -5809
NPSR1 -5997
LTB4R2 -6070
OPN4 -6111
FFAR2 -6188
PTGER3 -6420
CXCL6 -6452
TSHB -6594
TAAR2 -6612
NPFF -6680
HCRTR2 -6780
FPR1 -7227
PROKR2 -7528
MTNR1A -7596
CCL25 -7600
LPAR6 -7655
MCHR2 -7692
CCR8 -7760
P2RY1 -7798
HTR1A -7875
MC4R -7897
SAA1 -8169
SSTR3 -8361
RRH -8495
XCL2 -8522
GPR18 -8731
F2RL2 -8795
ADORA2B -8845
CXCL8 -8858
CCR1 -8936
F2RL3 -9428
GRP -9489
SSTR5 -9590
PTGER2 -9686
NPS -9769
PTGDR2 -9903
GHRL -10066
GPHA2 -10079
NMBR -10107
HTR1B -10130
OPRK1 -10174
TACR3 -10390
PRLHR -10409
LHB -10472
ACKR3 -10691
CYSLTR2 -10747
FSHB -10894
CXCL10 -10962
TAAR8 -11090
OXT -11123
HRH4 -11167
CCL4 -11241


REACTOME_DISEASES_OF_PROGRAMMED_CELL_DEATH

REACTOME_DISEASES_OF_PROGRAMMED_CELL_DEATH
1502
set REACTOME_DISEASES_OF_PROGRAMMED_CELL_DEATH
setSize 96
pANOVA 1.99e-09
s.dist -0.354
p.adjustANOVA 7.26e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
PRIM2 -9944.0
RIPK3 -9569.0
H2BC26 -9346.0
H2BC4 -9285.0
H2BC9 -9020.5

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
PRIM2 -9944.0
RIPK3 -9569.0
H2BC26 -9346.0
H2BC4 -9285.0
H2BC9 -9020.5
H3C7 -9020.5
PRIM1 -8994.0
SUZ12 -8594.0
H2BC3 -8572.0
H4C3 -8451.0
H2AC6 -8428.0
GOLGA2 -8279.0
C1QBP -8207.0
FADD -8187.0
H2BC10 -8174.0
CAPN1 -8050.0
H4C11 -7658.0
H2BC13 -7580.0
TRAF2 -7574.0
H3C1 -7492.0
H2BC5 -7339.0
RBBP4 -7271.0
CDC25C -7260.0
RIPK1 -7072.0
CDC25A -6793.0
POLA2 -6677.0
DNMT1 -6562.0
DNMT3B -6553.0
H2BC1 -6434.0
LMNB1 -6160.0
CDKN2A -5841.0
MLKL -5733.0
SOD2 -5618.0
H3-3B -5536.0
H2BC8 -5414.0
H3C4 -5404.0
H3-3A -5377.0
APP -5218.0
PRDX2 -4823.0
H2AC4 -4647.0
H3C8 -4535.0
FOXO3 -4392.0
H2BC11 -4063.0
H4C13 -3564.0
PRDX1 -3352.0
CASP8 -3265.0
JUN -2945.0
CDK5 -2911.0
EED -2898.0
EZH2 -2496.0
H4C2 -2432.0
CDC25B -2168.0
H2AZ2 -1872.0
H2AC8 -1109.0
H2AJ -963.0
YWHAE -811.0
H4C12 -107.0
H4C1 323.0
BCL2L11 400.0
CAST 440.0
H4C8 685.0
H2BC17 842.0
H2AX 876.0
H3C11 1739.0
H3C10 2461.0
H4C5 2528.0
DNMT3A 3442.0
CAPNS1 3700.0
H3C2 3733.0
H4C4 4097.0
H2AZ1 4397.0
H4C16 4865.0
GSDME 5082.0
H4C6 5430.0
FASLG 5501.0
CDK5R1 5516.0
CAPN2 5571.0
TP53 5757.0
CAPNS2 7463.0
TRADD 7765.0
LMNA 7850.0


REACTOME_CHROMOSOME_MAINTENANCE

REACTOME_CHROMOSOME_MAINTENANCE
1165
set REACTOME_CHROMOSOME_MAINTENANCE
setSize 130
pANOVA 1.99e-09
s.dist -0.305
p.adjustANOVA 7.26e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
H2AC14 -10727.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
CHTF18 -10162.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
PRIM2 -9944.0
LIG1 -9941.0
H2BC26 -9346.0
H2BC4 -9285.0
ANKRD28 -9030.0
H2BC9 -9020.5
PRIM1 -8994.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
H2AC14 -10727.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
CHTF18 -10162.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
PRIM2 -9944.0
LIG1 -9941.0
H2BC26 -9346.0
H2BC4 -9285.0
ANKRD28 -9030.0
H2BC9 -9020.5
PRIM1 -8994.0
CENPM -8958.0
TEN1 -8771.0
CENPH -8650.0
H2BC3 -8572.0
CENPT -8464.0
H4C3 -8451.0
H2AC6 -8428.0
SHQ1 -8310.0
PCNA -8301.0
POLD3 -8233.0
H2BC10 -8174.0
TERF1 -8166.0
NHP2 -7974.0
CDK2 -7826.0
NPM1 -7766.0
H4C11 -7658.0
RFC3 -7597.0
H2BC13 -7580.0
FEN1 -7452.0
H2BC5 -7339.0
RBBP4 -7271.0
CENPQ -7210.0
BLM -7176.0
RFC1 -7068.0
POLR2H -6881.0
POLA2 -6677.0
CCNA2 -6534.0
H2BC1 -6434.0
POLD2 -6366.0
POLR2L -5972.0
ACD -5957.5
KNL1 -5659.0
POLR2K -5634.0
RFC4 -5573.0
RSF1 -5545.0
H3-3B -5536.0
H2BC8 -5414.0
H3-3A -5377.0
MIS18A -5237.0
MIS18BP1 -5124.0
HJURP -4969.0
H2AC4 -4647.0
POLD4 -4479.0
WRN -4227.0
CENPA -4213.0
H2BC11 -4063.0
POLR2G -3937.0
GAR1 -3815.0
POLR2B -3768.0
PPP6C -3610.0
H4C13 -3564.0
CHTF8 -3541.0
POT1 -3175.0
H4C2 -2432.0
TERF2 -2059.0
RPA1 -2002.0
ITGB3BP -1875.0
H2AZ2 -1872.0
RFC5 -1846.0
POLR2I -1736.0
CENPO -1579.0
RUVBL1 -1380.0
POLR2A -1290.0
CTC1 -1252.0
CENPC -1213.0
DNA2 -1113.0
H2AC8 -1109.0
TERF2IP -1096.0
H2AJ -963.0
CCNA1 -948.0
SMARCA5 -420.0
CENPN -295.0
RTEL1 -180.0
H4C12 -107.0
DSCC1 -35.0
CENPP 177.0
POLR2C 198.0
H4C1 323.0
OIP5 402.0
POLR2E 503.0
STN1 518.0
H4C8 685.0
H2BC17 842.0
H2AX 876.0
CENPL 945.0
TINF2 1072.0
RPA3 1184.0
POLD1 1233.0
DAXX 1573.0
CENPS 1636.0
PPP6R3 1643.0
RUVBL2 1772.0
CENPK 1845.0
RFC2 1966.0
RPA2 2309.0
POLR2D 2370.0
H4C5 2528.0
POLR2F 3184.0
POLR2J 3674.0
WRAP53 3970.0
NOP10 3980.0
H4C4 4097.0
H2AZ1 4397.0
H4C16 4865.0
CENPU 5042.0
TERT 5349.0
H4C6 5430.0
CENPW 5691.0
H3-4 7087.0
PIF1 7214.0


REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS

REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS
601
set REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS
setSize 188
pANOVA 2.34e-09
s.dist 0.252
p.adjustANOVA 8.34e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
MLN 10633
TAC3 10566
CCL22 10472
CCL19 10427
CCL13 10381
MLNR 10345
CCL5 10328
PROKR1 10320
PPY 10304
GALR3 10243
CCL27 10220
NPW 10146
HCRTR1 10123
INSL5 10093
PROK1 10059
CCR3 10028
CCL17 9933
CCL16 9860
GPR37L1 9855
CXCR2 9804

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MLN 10633
TAC3 10566
CCL22 10472
CCL19 10427
CCL13 10381
MLNR 10345
CCL5 10328
PROKR1 10320
PPY 10304
GALR3 10243
CCL27 10220
NPW 10146
HCRTR1 10123
INSL5 10093
PROK1 10059
CCR3 10028
CCL17 9933
CCL16 9860
GPR37L1 9855
CXCR2 9804
CCL20 9802
PPBP 9636
UTS2R 9612
TACR2 9481
CX3CL1 9438
PRLH 9415
RLN3 9370
ACKR2 9333
KEL 9303
CCL11 9274
CXCL9 9241
MCHR1 9232
XCL1 9205
C5AR2 9180
CCR2 9141
POMC 9122
CORT 9076
CCR9 8857
UTS2 8803
CXCR1 8715
CCR6 8634
CCRL2 8523
CXCR5 8494
CCL2 8464
CCL1 8429
CX3CR1 8393
QRFP 8344
NPY2R 8307
MC1R 8260
PYY 8254
NPFFR1 8139
ACKR4 8111
CCKAR 8039
NMUR1 7976
C3AR1 7878
NPY 7862
AGT 7651
CXCL16 7609
CXCL5 7515
NTSR1 7446
KISS1 7299
CCL7 7186
NPBWR2 7174
AGTR1 7090
RLN2 7058
TAC1 7056
PDYN 6987
AVP 6951
TACR1 6709
EDNRB 6681
RXFP4 6648
XCR1 6621
F2 6618
UTS2B 6611
TRHR 6603
CXCL12 6390
CCR5 6200
MC5R 6125
KNG1 6104
SSTR4 6055
C3 5919
ECE2 5899
CXCL2 5815
BDKRB1 5480
GALR2 4839
GALR1 4770
PNOC 4689
BDKRB2 4679
OPRL1 4656
PSAP 4611
MC3R 4559
NPY1R 4439
RXFP1 4321
GPER1 4314
CCR10 4310
CCK 4301
CXCL1 4149
KISS1R 4131
CCL28 4119
NPB 3833
F2R 3760
OPRD1 3682
NMU 3560
CXCL13 3454
NPY5R 3097
F2RL1 2813
NMB 2741
NPBWR1 2709
CCL3 2612
NTS 2442
PF4 2093
NTSR2 1837
ACKR1 1835
INSL3 1447
GAL 1395
EDN3 1384
CCR7 1236
EDN1 1227
SSTR1 1013
MC2R 1001
EDNRA 943
CCL21 902
HCRT 328
SSTR2 327
CCL23 230
OXTR 208
C5AR1 -26
APLNR -178
ECE1 -859
EDN2 -945
OPRM1 -1005
NLN -1281
CXCR4 -1674
PMCH -2149
C5 -2310
CXCR6 -2426
RXFP2 -2699
CCKBR -2902
AVPR1A -3043
NMS -3349
CXCL3 -3451
FPR3 -3459
GPR37 -3635
TRH -3869
CXCL11 -3898
QRFPR -4101
HEBP1 -4246
PENK -4279
CCR4 -4444
ANXA1 -4452
RXFP3 -4651
PROK2 -4868
GHSR -4922
APP -5218
AVPR1B -5243
NMUR2 -5317
SST -5379
FPR2 -5517
NPFFR2 -5562
NPSR1 -5997
CXCL6 -6452
NPFF -6680
HCRTR2 -6780
FPR1 -7227
PROKR2 -7528
CCL25 -7600
MCHR2 -7692
CCR8 -7760
MC4R -7897
SAA1 -8169
SSTR3 -8361
XCL2 -8522
F2RL2 -8795
CXCL8 -8858
CCR1 -8936
F2RL3 -9428
GRP -9489
SSTR5 -9590
NPS -9769
GHRL -10066
NMBR -10107
OPRK1 -10174
TACR3 -10390
PRLHR -10409
ACKR3 -10691
CXCL10 -10962
OXT -11123
CCL4 -11241


REACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION

REACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION
852
set REACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION
setSize 84
pANOVA 3.46e-09
s.dist -0.373
p.adjustANOVA 1.21e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
H2AC20 -10208.0
POLR1E -10205.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
POLR1B -9824.0
EP300 -9652.0
H2BC26 -9346.0
H2BC4 -9285.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
H2AC20 -10208.0
POLR1E -10205.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
POLR1B -9824.0
EP300 -9652.0
H2BC26 -9346.0
H2BC4 -9285.0
H2BC9 -9020.5
H3C7 -9020.5
TAF1B -8830.0
H2BC3 -8572.0
H4C3 -8451.0
H2AC6 -8428.0
H2BC10 -8174.0
H4C11 -7658.0
H2BC13 -7580.0
H3C1 -7492.0
H2BC5 -7339.0
KAT2B -7302.0
POLR1C -7120.0
POLR2H -6881.0
TAF1D -6750.0
POLR1G -6552.0
H2BC1 -6434.0
DEK -6397.0
POLR2L -5972.0
POLR2K -5634.0
H3-3B -5536.0
H2BC8 -5414.0
H3C4 -5404.0
H3-3A -5377.0
H2AC4 -4647.0
H3C8 -4535.0
H2BC11 -4063.0
BAZ1B -3951.0
H4C13 -3564.0
SF3B1 -3274.0
POLR1H -2697.0
GSK3B -2656.0
POLR1A -2555.0
H4C2 -2432.0
H2AZ2 -1872.0
ERCC6 -1248.0
H2AC8 -1109.0
H2AJ -963.0
TBP -483.0
SMARCA5 -420.0
DDX21 -396.0
TAF1A -129.0
H4C12 -107.0
POLR1D 218.0
MYO1C 322.0
H4C1 323.0
POLR2E 503.0
H4C8 685.0
H2BC17 842.0
H2AX 876.0
KAT2A 1331.0
H3C11 1739.0
POLR1F 1814.0
H3C10 2461.0
TAF1C 2477.0
H4C5 2528.0
MYBBP1A 3133.0
ACTB 3141.0
POLR2F 3184.0
H3C2 3733.0
H4C4 4097.0
H2AZ1 4397.0
H4C16 4865.0
H4C6 5430.0


REACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION

REACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION
1395
set REACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION
setSize 140
pANOVA 3.82e-09
s.dist -0.288
p.adjustANOVA 1.31e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
CXXC5 -10405.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
MOV10 -10287.0
GTF2A2 -10268.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
GATA3 -9812.0
CTSD -9784.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
CXXC5 -10405.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
MOV10 -10287.0
GTF2A2 -10268.0
H2BC12 -10245.0
H2AC20 -10208.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
GATA3 -9812.0
CTSD -9784.0
RAD21 -9775.0
SP1 -9694.0
EP300 -9652.0
YY1 -9573.0
EBAG9 -9418.0
H2BC26 -9346.0
H2BC4 -9285.0
MYB -9069.0
H2BC9 -9020.5
H3C7 -9020.5
USF2 -8780.0
NCOA2 -8586.0
H2BC3 -8572.0
H4C3 -8451.0
H2AC6 -8428.0
RUNX1 -8234.0
H2BC10 -8174.0
PRMT1 -8128.0
KAT5 -8114.0
CBFB -7940.0
TNRC6B -7724.0
H4C11 -7658.0
TLE3 -7637.0
H2BC13 -7580.0
AGO4 -7579.0
H3C1 -7492.0
H2BC5 -7339.0
KAT2B -7302.0
KDM1A -7160.0
FKBP4 -6928.0
POLR2H -6881.0
CHD1 -6533.0
H2BC1 -6434.0
POLR2L -5972.0
HDAC1 -5913.0
POLR2K -5634.0
GPAM -5596.0
H3-3B -5536.0
H2BC8 -5414.0
H3C4 -5404.0
H3-3A -5377.0
H2AC4 -4647.0
H3C8 -4535.0
MED1 -4465.0
ERBB4 -4311.0
FOSB -4162.0
STAG1 -4121.0
H2BC11 -4063.0
POLR2G -3937.0
POLR2B -3768.0
H4C13 -3564.0
NCOA1 -3556.0
POU2F1 -3316.0
JUND -3304.0
AGO3 -3073.0
JUN -2945.0
NRIP1 -2871.0
NCOA3 -2868.0
GTF2F2 -2764.0
HSP90AA1 -2504.0
H4C2 -2432.0
CARM1 -2380.0
HSP90AB1 -1956.0
H2AZ2 -1872.0
POLR2I -1736.0
CREBBP -1603.0
GTF2A1 -1415.0
POLR2A -1290.0
H2AC8 -1109.0
H2AJ -963.0
FOS -894.0
MYC -745.0
TBP -483.0
TNRC6A -436.0
PGR -310.0
H4C12 -107.0
POLR2C 198.0
AGO2 199.0
H4C1 323.0
AGO1 376.0
KANK1 414.0
KCTD6 430.0
POLR2E 503.0
ESR1 559.0
H4C8 685.0
H2BC17 842.0
H2AX 876.0
GTF2F1 936.0
CDK9 1265.0
TGFA 1315.0
CCNT1 1385.0
PTGES3 1666.0
H3C11 1739.0
SMC3 1750.0
FOXA1 2217.0
POLR2D 2370.0
H3C10 2461.0
H4C5 2528.0
KPNA2 2633.0
AXIN1 3098.0
POLR2F 3184.0
TNRC6C 3185.0
CCND1 3284.0
ATF2 3306.0
KDM4B 3377.0
NR5A2 3584.0
POLR2J 3674.0
H3C2 3733.0
BCL2 3735.0
DDX5 3974.0
H4C4 4097.0
H2AZ1 4397.0
H4C16 4865.0
USF1 5361.0
H4C6 5430.0
ZNF217 5543.0
CXCL12 6390.0
GREB1 7519.0
TFF1 8818.0
TFF3 9192.0


REACTOME_RRNA_PROCESSING

REACTOME_RRNA_PROCESSING
1148
set REACTOME_RRNA_PROCESSING
setSize 192
pANOVA 4.42e-09
s.dist -0.245
p.adjustANOVA 1.46e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL10L -11011
RPL35A -10631
RPL37A -10509
WDR36 -10218
PELP1 -10186
RIOK2 -10097
RPL11 -9622
RIOK3 -9618
RPS5 -9536
RPP25 -9431
KRR1 -9372
ERI1 -9352
EXOSC7 -9248
UTP6 -9227
RPP30 -9130
THUMPD1 -9117
CSNK1D -9073
RPS23 -9056
UTP11 -9050
RPL24 -8875

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL10L -11011.0
RPL35A -10631.0
RPL37A -10509.0
WDR36 -10218.0
PELP1 -10186.0
RIOK2 -10097.0
RPL11 -9622.0
RIOK3 -9618.0
RPS5 -9536.0
RPP25 -9431.0
KRR1 -9372.0
ERI1 -9352.0
EXOSC7 -9248.0
UTP6 -9227.0
RPP30 -9130.0
THUMPD1 -9117.0
CSNK1D -9073.0
RPS23 -9056.0
UTP11 -9050.0
RPL24 -8875.0
TEX10 -8792.0
RPL32 -8790.0
RCL1 -8732.0
XRN2 -8689.0
RPL4 -8640.0
RPL23A -8537.0
EXOSC10 -8526.0
WDR12 -8411.0
NOL12 -8375.0
UTP18 -8231.0
FAU -8194.0
IMP4 -8142.0
FTSJ3 -8090.0
SNU13 -8074.0
RPL23 -8055.0
RPL13 -8037.0
FCF1 -8005.0
NHP2 -7974.0
RRP1 -7885.0
EXOSC4 -7820.0
RBM28 -7737.0
SENP3 -7699.0
MTERF4 -7672.0
WDR43 -7670.0
RPL7A -7402.0
RPL35 -7326.0
RPL31 -7280.0
RPS26 -7213.0
NOP2 -7204.0
RRP36 -7171.0
NOB1 -7091.0
EMG1 -7006.0
RPP14 -6913.0
RPSA -6847.0
UTP3 -6743.0
NSUN4 -6688.0
RPL36 -6664.0
RPS28 -6540.0
HEATR1 -6477.0
UTP15 -6383.0
DDX49 -6244.0
DIS3 -6209.0
RPL21 -6077.0
GNL3 -6053.0
RPL30 -5982.0
LTV1 -5766.0
RPL26 -5760.0
RPL10A -5530.0
MRM3 -5444.0
C1D -5297.0
RPS15 -5286.0
MRM2 -4995.0
RPL19 -4989.0
UTP14C -4942.0
RPLP0 -4937.0
PWP2 -4916.0
EXOSC2 -4886.0
RPS12 -4819.0
PRORP -4791.0
RPS16 -4777.0
NIP7 -4728.0
IMP3 -4695.0
RPL36AL -4483.5
NOP58 -4464.0
RPS10 -4458.0
RPL7 -4455.0
EXOSC5 -4400.0
RPS6 -4356.0
WDR3 -4332.0
RPS27L -4266.0
RPL18 -4060.0
EXOSC9 -3979.0
EXOSC6 -3940.0
MRM1 -3896.0
RPS21 -3875.0
GAR1 -3815.0
RPP40 -3791.0
RPS8 -3769.0
RPS18 -3746.0
WDR75 -3741.0
DIMT1 -3720.0
RPL17 -3669.0
DCAF13 -3631.0
MTREX -3624.0
TFB1M -3491.0
BOP1 -3328.0
EBNA1BP2 -3087.0
RPL27 -3082.0
UTP25 -2986.0
TRMT10C -2830.0
EXOSC3 -2772.0
UTP20 -2609.0
TSR3 -2583.0
RPL14 -2574.0
RPLP2 -2532.0
NOL11 -2462.0
DHX37 -2258.0
FBL -2120.0
ISG20L2 -1566.0
UTP4 -1525.0
RPS20 -1511.0
RPS9 -1361.0
RPL5 -1340.0
MPHOSPH6 -1305.0
NCL -1018.0
EXOSC8 -994.0
BUD23 -952.0
RPL8 -941.0
RPS11 -773.0
RIOK1 -677.0
RPS14 -538.0
TSR1 -440.0
DDX21 -396.0
MPHOSPH10 -355.0
TRMT112 -273.0
RPS27A -126.0
RPLP1 175.0
TBL3 184.0
RPS7 193.0
ELAC2 281.0
RPL12 342.0
PNO1 434.0
RPS19 887.0
PDCD11 1162.0
RPL15 1283.0
RPL28 1298.0
RPL22 1475.0
NOL6 1478.0
DDX47 1771.0
PES1 1930.0
NOP14 1995.0
NAT10 2078.0
WDR46 2080.0
RPL41 2146.0
RPL37 2151.0
RPS27 2171.0
NOL9 2197.0
EXOSC1 2226.0
RPS15A 2354.0
RPS29 2538.0
RPS3 2573.0
RPL34 2588.0
RPL27A 2771.0
RRP7A 2943.0
RPP21 3226.0
RPP38 3277.0
RPS3A 3411.0
RPS13 3598.0
RPS2 3762.0
DDX52 3848.0
BMS1 3971.0
NOP10 3980.0
RPL6 4045.0
RPS25 4057.0
WDR18 4069.0
RPL26L1 4216.0
RPS24 4241.0
RPL22L1 4607.0
RPL18A 4718.0
RRP9 4739.0
RPL38 4807.0
RPL9 5114.0
CSNK1E 5169.0
NOP56 5614.0
RPL39L 6167.0
RPL3 6195.0
UBA52 6282.0
BYSL 6303.0
RPL13A 6422.5
NOC4L 6906.0
RPL29 8479.0
RPL3L 10336.0


REACTOME_SIRT1_NEGATIVELY_REGULATES_RRNA_EXPRESSION

REACTOME_SIRT1_NEGATIVELY_REGULATES_RRNA_EXPRESSION
737
set REACTOME_SIRT1_NEGATIVELY_REGULATES_RRNA_EXPRESSION
setSize 60
pANOVA 4.43e-09
s.dist -0.438
p.adjustANOVA 1.46e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
RRP8 -10241.0
H2AC20 -10208.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
H2BC26 -9346.0
H2BC4 -9285.0
H2BC9 -9020.5
H3C7 -9020.5

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 -11029.0
H3C6 -10917.0
H3C12 -10877.0
H3C3 -10808.0
H2AC14 -10727.0
H2BC6 -10375.0
H2AC18 -10337.5
H2AC19 -10337.5
H4C9 -10304.0
H2BC12 -10245.0
RRP8 -10241.0
H2AC20 -10208.0
H2BC15 -10189.0
H2AC7 -10035.5
H2BC7 -10035.5
H2BC21 -10020.0
H2BC26 -9346.0
H2BC4 -9285.0
H2BC9 -9020.5
H3C7 -9020.5
TAF1B -8830.0
H2BC3 -8572.0
H4C3 -8451.0
H2AC6 -8428.0
H2BC10 -8174.0
H4C11 -7658.0
H2BC13 -7580.0
H3C1 -7492.0
H2BC5 -7339.0
TAF1D -6750.0
SIRT1 -6458.0
H2BC1 -6434.0
H3-3B -5536.0
H2BC8 -5414.0
H3C4 -5404.0
H3-3A -5377.0
H2AC4 -4647.0
H3C8 -4535.0
H2BC11 -4063.0
H4C13 -3564.0
H4C2 -2432.0
H2AZ2 -1872.0
H2AC8 -1109.0
H2AJ -963.0
TBP -483.0
TAF1A -129.0
H4C12 -107.0
H4C1 323.0
H4C8 685.0
H2BC17 842.0
H2AX 876.0
H3C11 1739.0
H3C10 2461.0
TAF1C 2477.0
H4C5 2528.0
H3C2 3733.0
H4C4 4097.0
H2AZ1 4397.0
H4C16 4865.0
H4C6 5430.0


Here is the session info with all the versions of packages used.

sessionInfo()
## R version 4.3.2 (2023-10-31)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.3 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3 
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so;  LAPACK version 3.10.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Etc/UTC
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.3.3                                      
##  [2] GGally_2.2.0                                       
##  [3] ggplot2_3.4.4                                      
##  [4] reshape2_1.4.4                                     
##  [5] gtools_3.9.5                                       
##  [6] tibble_3.2.1                                       
##  [7] dplyr_1.1.4                                        
##  [8] echarts4r_0.4.5                                    
##  [9] png_0.1-8                                          
## [10] gridExtra_2.3                                      
## [11] missMethyl_1.36.0                                  
## [12] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.1 
## [13] beeswarm_0.4.0                                     
## [14] kableExtra_1.3.4                                   
## [15] gplots_3.1.3                                       
## [16] mitch_1.15.0                                       
## [17] tictoc_1.2                                         
## [18] HGNChelper_0.8.1                                   
## [19] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [20] IlluminaHumanMethylation450kmanifest_0.4.0         
## [21] minfi_1.48.0                                       
## [22] bumphunter_1.44.0                                  
## [23] locfit_1.5-9.8                                     
## [24] iterators_1.0.14                                   
## [25] foreach_1.5.2                                      
## [26] Biostrings_2.70.1                                  
## [27] XVector_0.42.0                                     
## [28] SummarizedExperiment_1.32.0                        
## [29] Biobase_2.62.0                                     
## [30] MatrixGenerics_1.14.0                              
## [31] matrixStats_1.2.0                                  
## [32] GenomicRanges_1.54.1                               
## [33] GenomeInfoDb_1.38.2                                
## [34] IRanges_2.36.0                                     
## [35] S4Vectors_0.40.2                                   
## [36] BiocGenerics_0.48.1                                
## [37] eulerr_7.0.0                                       
## [38] limma_3.58.1                                       
## 
## loaded via a namespace (and not attached):
##   [1] splines_4.3.2             later_1.3.2              
##   [3] BiocIO_1.12.0             bitops_1.0-7             
##   [5] filelock_1.0.3            preprocessCore_1.64.0    
##   [7] XML_3.99-0.16             lifecycle_1.0.4          
##   [9] lattice_0.22-5            MASS_7.3-60              
##  [11] base64_2.0.1              scrime_1.3.5             
##  [13] magrittr_2.0.3            sass_0.4.8               
##  [15] rmarkdown_2.25            jquerylib_0.1.4          
##  [17] yaml_2.3.8                httpuv_1.6.13            
##  [19] doRNG_1.8.6               askpass_1.2.0            
##  [21] DBI_1.1.3                 RColorBrewer_1.1-3       
##  [23] abind_1.4-5               zlibbioc_1.48.0          
##  [25] rvest_1.0.3               quadprog_1.5-8           
##  [27] purrr_1.0.2               RCurl_1.98-1.13          
##  [29] rappdirs_0.3.3            GenomeInfoDbData_1.2.11  
##  [31] genefilter_1.84.0         annotate_1.80.0          
##  [33] svglite_2.1.3             DelayedMatrixStats_1.24.0
##  [35] codetools_0.2-19          DelayedArray_0.28.0      
##  [37] xml2_1.3.6                tidyselect_1.2.0         
##  [39] beanplot_1.3.1            BiocFileCache_2.10.1     
##  [41] webshot_0.5.5             illuminaio_0.44.0        
##  [43] GenomicAlignments_1.38.0  jsonlite_1.8.8           
##  [45] multtest_2.58.0           ellipsis_0.3.2           
##  [47] survival_3.5-7            systemfonts_1.0.5        
##  [49] tools_4.3.2               progress_1.2.3           
##  [51] Rcpp_1.0.11               glue_1.6.2               
##  [53] SparseArray_1.2.2         xfun_0.41                
##  [55] HDF5Array_1.30.0          withr_2.5.2              
##  [57] fastmap_1.1.1             rhdf5filters_1.14.1      
##  [59] fansi_1.0.6               openssl_2.1.1            
##  [61] caTools_1.18.2            digest_0.6.33            
##  [63] R6_2.5.1                  mime_0.12                
##  [65] colorspace_2.1-0          biomaRt_2.58.0           
##  [67] RSQLite_2.3.4             utf8_1.2.4               
##  [69] tidyr_1.3.0               generics_0.1.3           
##  [71] data.table_1.14.10        rtracklayer_1.62.0       
##  [73] prettyunits_1.2.0         httr_1.4.7               
##  [75] htmlwidgets_1.6.4         S4Arrays_1.2.0           
##  [77] ggstats_0.5.1             pkgconfig_2.0.3          
##  [79] gtable_0.3.4              blob_1.2.4               
##  [81] siggenes_1.76.0           htmltools_0.5.7          
##  [83] scales_1.3.0              rstudioapi_0.15.0        
##  [85] knitr_1.45                tzdb_0.4.0               
##  [87] rjson_0.2.21              nlme_3.1-163             
##  [89] curl_5.2.0                org.Hs.eg.db_3.18.0      
##  [91] cachem_1.0.8              rhdf5_2.46.1             
##  [93] stringr_1.5.1             KernSmooth_2.23-22       
##  [95] AnnotationDbi_1.64.1      restfulr_0.0.15          
##  [97] GEOquery_2.70.0           pillar_1.9.0             
##  [99] grid_4.3.2                reshape_0.8.9            
## [101] vctrs_0.6.5               promises_1.2.1           
## [103] dbplyr_2.4.0              xtable_1.8-4             
## [105] evaluate_0.23             readr_2.1.4              
## [107] GenomicFeatures_1.54.1    cli_3.6.2                
## [109] compiler_4.3.2            Rsamtools_2.18.0         
## [111] rlang_1.1.2               crayon_1.5.2             
## [113] rngtools_1.5.2            nor1mix_1.3-2            
## [115] mclust_6.0.1              plyr_1.8.9               
## [117] stringi_1.8.3             viridisLite_0.4.2        
## [119] BiocParallel_1.36.0       munsell_0.5.0            
## [121] Matrix_1.6-1.1            hms_1.1.3                
## [123] sparseMatrixStats_1.14.0  bit64_4.0.5              
## [125] Rhdf5lib_1.24.1           KEGGREST_1.42.0          
## [127] statmod_1.5.0             shiny_1.8.0              
## [129] highr_0.10                memoise_2.0.1            
## [131] bslib_0.6.1               bit_4.0.5

END of report