date generated: 2024-01-18

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch
x
A1BG -0.0006319
A1BG-AS1 0.0000452
A1CF -0.0016289
A2M -0.0018113
A2M-AS1 -0.0121570
A2ML1 -0.0005637

Here are some metrics about the input data profile:

Profiling data metrics
Profile metrics
num_genesets 1654
num_genes_in_profile 22007
duplicated_genes_present 0
num_profile_genes_in_sets 10383
num_profile_genes_not_in_sets 11624

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets: c2.cp.reactome.v2023.1.Hs.symbols.gmt
Gene set metrics
Gene sets metrics
num_genesets 1654
num_genesets_excluded 365
num_genesets_included 1289

Differential pathway expression


Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

## Warning in kable_styling(., "hover", full_width = FALSE): Please specify format
## in kable. kableExtra can customize either HTML or LaTeX outputs. See
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set setSize pANOVA s.dist p.adjustANOVA
REACTOME METABOLISM OF RNA 675 2.44e-13 0.1650 4.00e-10
REACTOME OLFACTORY SIGNALING PATHWAY 348 1.03e-09 -0.1900 8.45e-07
REACTOME TRANSLATION 278 2.31e-09 0.2080 1.27e-06
REACTOME SENSORY PERCEPTION 555 5.35e-09 -0.1450 2.20e-06
REACTOME CELL CYCLE 666 2.22e-08 0.1270 7.29e-06
REACTOME INNATE IMMUNE SYSTEM 1002 4.14e-08 0.1020 1.13e-05
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM 688 1.40e-07 0.1180 3.28e-05
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA 263 1.95e-07 0.1860 3.99e-05
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE 105 3.46e-07 0.2880 6.30e-05
REACTOME INFLUENZA INFECTION 149 4.21e-07 0.2400 6.91e-05
REACTOME NONSENSE MEDIATED DECAY NMD 107 4.77e-07 0.2820 7.12e-05
REACTOME CELL CYCLE MITOTIC 539 5.75e-07 0.1260 7.87e-05
REACTOME CELLULAR RESPONSES TO STIMULI 779 1.72e-06 0.1010 2.18e-04
REACTOME INFECTIOUS DISEASE 910 2.11e-06 0.0927 2.47e-04
REACTOME NEUTROPHIL DEGRANULATION 460 2.72e-06 0.1280 2.98e-04
REACTOME RRNA PROCESSING 192 3.16e-06 0.1950 3.25e-04
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY 94 3.73e-06 0.2760 3.61e-04
REACTOME FORMATION OF THE CORNIFIED ENVELOPE 125 7.88e-06 -0.2310 7.19e-04
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL 122 1.09e-05 0.2310 8.45e-04
REACTOME EUKARYOTIC TRANSLATION INITIATION 110 1.11e-05 0.2430 8.45e-04
REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY 46 1.13e-05 0.3740 8.45e-04
REACTOME MRNA SPLICING 197 1.18e-05 0.1810 8.45e-04
REACTOME SARS COV 1 HOST INTERACTIONS 92 1.18e-05 0.2640 8.45e-04
REACTOME EUKARYOTIC TRANSLATION ELONGATION 87 1.25e-05 0.2710 8.54e-04
REACTOME EXTRACELLULAR MATRIX ORGANIZATION 291 1.32e-05 -0.1480 8.69e-04
REACTOME SARS COV 2 HOST INTERACTIONS 191 2.40e-05 0.1770 1.47e-03
REACTOME CELL CYCLE CHECKPOINTS 284 2.43e-05 0.1460 1.47e-03
REACTOME ADAPTIVE IMMUNE SYSTEM 729 2.64e-05 0.0914 1.52e-03
REACTOME RNA POLYMERASE II TRANSCRIPTION 1336 2.71e-05 0.0684 1.52e-03
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS 161 2.79e-05 0.1910 1.52e-03
REACTOME MITOTIC METAPHASE AND ANAPHASE 228 3.76e-05 0.1580 1.99e-03
REACTOME TCR SIGNALING 113 6.44e-05 0.2180 3.30e-03
REACTOME SARS COV 1 INFECTION 136 6.70e-05 0.1980 3.33e-03
REACTOME SIGNALING BY INTERLEUKINS 444 8.95e-05 0.1080 4.32e-03
REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS 66 9.73e-05 -0.2770 4.56e-03
REACTOME M PHASE 398 1.03e-04 0.1130 4.56e-03
REACTOME MITOCHONDRIAL TRANSLATION 93 1.03e-04 0.2330 4.56e-03
REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX 134 1.82e-04 -0.1870 7.86e-03
REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES 39 2.09e-04 0.3430 8.67e-03
REACTOME SARS COV 2 INFECTION 281 2.11e-04 0.1280 8.67e-03
REACTOME DNA REPLICATION PRE INITIATION 150 2.57e-04 0.1730 1.02e-02
REACTOME SEPARATION OF SISTER CHROMATIDS 184 2.61e-04 0.1560 1.02e-02
REACTOME SARS COV INFECTIONS 392 2.78e-04 0.1070 1.06e-02
REACTOME O LINKED GLYCOSYLATION 109 3.16e-04 -0.2000 1.18e-02
REACTOME ECM PROTEOGLYCANS 73 4.80e-04 -0.2360 1.73e-02
REACTOME SIGNALING BY ROBO RECEPTORS 206 4.86e-04 0.1410 1.73e-02
REACTOME DNA REPLICATION 178 5.07e-04 0.1510 1.77e-02
REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER 81 5.69e-04 0.2210 1.95e-02
REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION 62 6.33e-04 0.2510 2.12e-02
REACTOME MITOTIC G2 G2 M PHASES 194 6.72e-04 0.1420 2.21e-02


Results (complete table)


Click HERE to show results for all gene sets

Complete results
set setSize pANOVA s.dist p.adjustANOVA
REACTOME METABOLISM OF RNA 675 2.44e-13 0.165000 4.00e-10
REACTOME OLFACTORY SIGNALING PATHWAY 348 1.03e-09 -0.190000 8.45e-07
REACTOME TRANSLATION 278 2.31e-09 0.208000 1.27e-06
REACTOME SENSORY PERCEPTION 555 5.35e-09 -0.145000 2.20e-06
REACTOME CELL CYCLE 666 2.22e-08 0.127000 7.29e-06
REACTOME INNATE IMMUNE SYSTEM 1002 4.14e-08 0.102000 1.13e-05
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM 688 1.40e-07 0.118000 3.28e-05
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA 263 1.95e-07 0.186000 3.99e-05
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE 105 3.46e-07 0.288000 6.30e-05
REACTOME INFLUENZA INFECTION 149 4.21e-07 0.240000 6.91e-05
REACTOME NONSENSE MEDIATED DECAY NMD 107 4.77e-07 0.282000 7.12e-05
REACTOME CELL CYCLE MITOTIC 539 5.75e-07 0.126000 7.87e-05
REACTOME CELLULAR RESPONSES TO STIMULI 779 1.72e-06 0.101000 2.18e-04
REACTOME INFECTIOUS DISEASE 910 2.11e-06 0.092700 2.47e-04
REACTOME NEUTROPHIL DEGRANULATION 460 2.72e-06 0.128000 2.98e-04
REACTOME RRNA PROCESSING 192 3.16e-06 0.195000 3.25e-04
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY 94 3.73e-06 0.276000 3.61e-04
REACTOME FORMATION OF THE CORNIFIED ENVELOPE 125 7.88e-06 -0.231000 7.19e-04
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL 122 1.09e-05 0.231000 8.45e-04
REACTOME EUKARYOTIC TRANSLATION INITIATION 110 1.11e-05 0.243000 8.45e-04
REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY 46 1.13e-05 0.374000 8.45e-04
REACTOME MRNA SPLICING 197 1.18e-05 0.181000 8.45e-04
REACTOME SARS COV 1 HOST INTERACTIONS 92 1.18e-05 0.264000 8.45e-04
REACTOME EUKARYOTIC TRANSLATION ELONGATION 87 1.25e-05 0.271000 8.54e-04
REACTOME EXTRACELLULAR MATRIX ORGANIZATION 291 1.32e-05 -0.148000 8.69e-04
REACTOME SARS COV 2 HOST INTERACTIONS 191 2.40e-05 0.177000 1.47e-03
REACTOME CELL CYCLE CHECKPOINTS 284 2.43e-05 0.146000 1.47e-03
REACTOME ADAPTIVE IMMUNE SYSTEM 729 2.64e-05 0.091400 1.52e-03
REACTOME RNA POLYMERASE II TRANSCRIPTION 1336 2.71e-05 0.068400 1.52e-03
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS 161 2.79e-05 0.191000 1.52e-03
REACTOME MITOTIC METAPHASE AND ANAPHASE 228 3.76e-05 0.158000 1.99e-03
REACTOME TCR SIGNALING 113 6.44e-05 0.218000 3.30e-03
REACTOME SARS COV 1 INFECTION 136 6.70e-05 0.198000 3.33e-03
REACTOME SIGNALING BY INTERLEUKINS 444 8.95e-05 0.108000 4.32e-03
REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS 66 9.73e-05 -0.277000 4.56e-03
REACTOME M PHASE 398 1.03e-04 0.113000 4.56e-03
REACTOME MITOCHONDRIAL TRANSLATION 93 1.03e-04 0.233000 4.56e-03
REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX 134 1.82e-04 -0.187000 7.86e-03
REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES 39 2.09e-04 0.343000 8.67e-03
REACTOME SARS COV 2 INFECTION 281 2.11e-04 0.128000 8.67e-03
REACTOME DNA REPLICATION PRE INITIATION 150 2.57e-04 0.173000 1.02e-02
REACTOME SEPARATION OF SISTER CHROMATIDS 184 2.61e-04 0.156000 1.02e-02
REACTOME SARS COV INFECTIONS 392 2.78e-04 0.107000 1.06e-02
REACTOME O LINKED GLYCOSYLATION 109 3.16e-04 -0.200000 1.18e-02
REACTOME ECM PROTEOGLYCANS 73 4.80e-04 -0.236000 1.73e-02
REACTOME SIGNALING BY ROBO RECEPTORS 206 4.86e-04 0.141000 1.73e-02
REACTOME DNA REPLICATION 178 5.07e-04 0.151000 1.77e-02
REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER 81 5.69e-04 0.221000 1.95e-02
REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION 62 6.33e-04 0.251000 2.12e-02
REACTOME MITOTIC G2 G2 M PHASES 194 6.72e-04 0.142000 2.21e-02
REACTOME DISEASES OF GLYCOSYLATION 137 6.93e-04 -0.168000 2.23e-02
REACTOME SELENOAMINO ACID METABOLISM 108 8.04e-04 0.187000 2.51e-02
REACTOME KERATINIZATION 210 8.12e-04 -0.134000 2.51e-02
REACTOME CELLULAR RESPONSE TO STARVATION 147 9.18e-04 0.158000 2.79e-02
REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM 78 1.05e-03 0.215000 3.14e-02
REACTOME CALNEXIN CALRETICULIN CYCLE 26 1.21e-03 0.367000 3.53e-02
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY 33 1.22e-03 0.325000 3.53e-02
REACTOME S PHASE 159 1.28e-03 0.148000 3.60e-02
REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION 145 1.29e-03 0.155000 3.60e-02
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S 53 1.47e-03 0.253000 4.02e-02
REACTOME DAP12 INTERACTIONS 37 1.50e-03 0.302000 4.03e-02
REACTOME INTERFERON ALPHA BETA SIGNALING 70 1.67e-03 0.217000 4.43e-02
REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS 6 1.84e-03 -0.734000 4.74e-02
REACTOME G2 M CHECKPOINTS 162 1.85e-03 0.142000 4.74e-02
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS 121 2.04e-03 0.162000 5.15e-02
REACTOME TNFR2 NON CANONICAL NF KB PATHWAY 96 2.12e-03 0.181000 5.28e-02
REACTOME THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT 77 2.39e-03 0.200000 5.86e-02
REACTOME PHASE 4 RESTING MEMBRANE POTENTIAL 19 2.69e-03 -0.398000 6.49e-02
REACTOME INTERFERON SIGNALING 193 2.79e-03 0.125000 6.64e-02
REACTOME SYNTHESIS OF DNA 119 2.85e-03 0.158000 6.69e-02
REACTOME RESOLUTION OF SISTER CHROMATID COHESION 120 2.91e-03 0.157000 6.73e-02
REACTOME HCMV INFECTION 152 2.95e-03 0.140000 6.73e-02
REACTOME TRANSPORT OF SMALL MOLECULES 697 3.05e-03 -0.065800 6.86e-02
REACTOME SNRNP ASSEMBLY 53 3.26e-03 0.234000 7.22e-02
REACTOME E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS 58 3.49e-03 0.222000 7.59e-02
REACTOME APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS 87 3.51e-03 0.181000 7.59e-02
REACTOME RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX 29 4.00e-03 0.309000 8.54e-02
REACTOME HOMOLOGY DIRECTED REPAIR 132 4.47e-03 0.143000 9.37e-02
REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21 59 4.51e-03 0.214000 9.37e-02
REACTOME GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER 25 4.58e-03 0.328000 9.40e-02
REACTOME SARS COV 2 ACTIVATES MODULATES INNATE AND ADAPTIVE IMMUNE RESPONSES 118 4.65e-03 0.151000 9.43e-02
REACTOME NUCLEOTIDE EXCISION REPAIR 107 4.85e-03 0.158000 9.72e-02
REACTOME CLEC7A DECTIN 1 SIGNALING 97 5.09e-03 0.165000 1.00e-01
REACTOME HIV INFECTION 223 5.14e-03 0.109000 1.00e-01
REACTOME GENERATION OF SECOND MESSENGER MOLECULES 30 5.19e-03 0.295000 1.00e-01
REACTOME HCMV LATE EVENTS 110 5.34e-03 0.154000 1.02e-01
REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON 17 5.81e-03 0.386000 1.09e-01
REACTOME DISEASES OF METABOLISM 237 5.88e-03 -0.104000 1.09e-01
REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS 53 5.92e-03 0.219000 1.09e-01
REACTOME DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA 77 6.41e-03 0.180000 1.17e-01
REACTOME FLT3 SIGNALING 38 6.55e-03 0.255000 1.18e-01
REACTOME MEIOTIC RECOMBINATION 80 6.88e-03 0.175000 1.19e-01
REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS 93 7.01e-03 0.162000 1.19e-01
REACTOME FCERI MEDIATED NF KB ACTIVATION 78 7.04e-03 0.176000 1.19e-01
REACTOME SIGNALING BY THE B CELL RECEPTOR BCR 106 7.08e-03 0.151000 1.19e-01
REACTOME ENDOSOMAL VACUOLAR PATHWAY 11 7.13e-03 0.469000 1.19e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING 11 7.13e-03 0.468000 1.19e-01
REACTOME SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE 91 7.19e-03 0.163000 1.19e-01
REACTOME PROCESSING OF DNA DOUBLE STRAND BREAK ENDS 93 7.21e-03 0.161000 1.19e-01
REACTOME PROTEIN UBIQUITINATION 76 7.25e-03 0.178000 1.19e-01
REACTOME TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7 12 7.38e-03 0.447000 1.20e-01
REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP 104 7.62e-03 0.151000 1.22e-01
REACTOME CELLULAR SENESCENCE 189 7.67e-03 0.112000 1.22e-01
REACTOME O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS 38 7.84e-03 -0.249000 1.23e-01
REACTOME INTERLEUKIN 12 FAMILY SIGNALING 53 7.93e-03 0.211000 1.23e-01
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES 55 8.09e-03 0.206000 1.23e-01
REACTOME REGULATION OF RUNX3 EXPRESSION AND ACTIVITY 54 8.19e-03 0.208000 1.23e-01
REACTOME MITOTIC PROMETAPHASE 194 8.21e-03 0.110000 1.23e-01
REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL 58 8.28e-03 0.200000 1.23e-01
REACTOME RHO GTPASE EFFECTORS 305 8.32e-03 0.087800 1.23e-01
REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT 236 8.48e-03 -0.099500 1.23e-01
REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 100 8.51e-03 0.152000 1.23e-01
REACTOME DUAL INCISION IN GG NER 39 8.55e-03 0.243000 1.23e-01
REACTOME NEGATIVE REGULATION OF NOTCH4 SIGNALING 53 8.56e-03 0.209000 1.23e-01
REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE 35 8.71e-03 0.256000 1.24e-01
REACTOME DNA DAMAGE BYPASS 47 9.46e-03 0.219000 1.34e-01
REACTOME NEGATIVE REGULATION OF FLT3 15 9.69e-03 0.386000 1.35e-01
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION 1356 9.74e-03 0.041800 1.35e-01
REACTOME REACTIONS SPECIFIC TO THE COMPLEX N GLYCAN SYNTHESIS PATHWAY 10 9.80e-03 -0.472000 1.35e-01
REACTOME TRANSLESION SYNTHESIS BY POLK 17 9.90e-03 0.361000 1.35e-01
REACTOME TERMINATION OF TRANSLESION DNA SYNTHESIS 32 1.00e-02 0.263000 1.35e-01
REACTOME RNA POLYMERASE I PROMOTER ESCAPE 83 1.01e-02 0.163000 1.35e-01
REACTOME HCMV EARLY EVENTS 128 1.01e-02 0.132000 1.35e-01
REACTOME ER QUALITY CONTROL COMPARTMENT ERQC 21 1.04e-02 0.323000 1.37e-01
REACTOME NUCLEAR EVENTS MEDIATED BY NFE2L2 77 1.06e-02 0.168000 1.39e-01
REACTOME MEIOSIS 110 1.08e-02 0.141000 1.41e-01
REACTOME REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE 81 1.16e-02 0.162000 1.49e-01
REACTOME MITOTIC SPINDLE CHECKPOINT 109 1.17e-02 0.140000 1.49e-01
REACTOME PARACETAMOL ADME 26 1.18e-02 -0.285000 1.49e-01
REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS 111 1.18e-02 0.138000 1.49e-01
REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS 100 1.19e-02 0.146000 1.49e-01
REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS 86 1.19e-02 0.157000 1.49e-01
REACTOME C TYPE LECTIN RECEPTORS CLRS 136 1.21e-02 0.125000 1.49e-01
REACTOME FORMATION OF INCISION COMPLEX IN GG NER 40 1.21e-02 0.229000 1.49e-01
REACTOME NUCLEAR ENVELOPE NE REASSEMBLY 74 1.25e-02 0.168000 1.51e-01
REACTOME MODULATION BY MTB OF HOST IMMUNE SYSTEM 6 1.25e-02 0.589000 1.51e-01
REACTOME TOLL LIKE RECEPTOR CASCADES 158 1.28e-02 0.115000 1.52e-01
REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT 159 1.28e-02 0.114000 1.52e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1 229 1.29e-02 0.095300 1.53e-01
REACTOME G2 M DNA DAMAGE CHECKPOINT 90 1.31e-02 0.151000 1.53e-01
REACTOME HS GAG BIOSYNTHESIS 28 1.32e-02 -0.271000 1.53e-01
REACTOME SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS 74 1.32e-02 0.167000 1.53e-01
REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX 15 1.34e-02 0.369000 1.53e-01
REACTOME AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA 54 1.34e-02 0.195000 1.53e-01
REACTOME CHROMOSOME MAINTENANCE 130 1.42e-02 0.124000 1.61e-01
REACTOME TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE 39 1.43e-02 0.227000 1.61e-01
REACTOME GPVI MEDIATED ACTIVATION CASCADE 35 1.48e-02 0.238000 1.64e-01
REACTOME FC EPSILON RECEPTOR FCERI SIGNALING 127 1.48e-02 0.125000 1.64e-01
REACTOME INTERLEUKIN 10 SIGNALING 43 1.55e-02 0.213000 1.71e-01
REACTOME HIV LIFE CYCLE 145 1.61e-02 0.116000 1.76e-01
REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION 26 1.62e-02 0.272000 1.77e-01
REACTOME DNA DOUBLE STRAND BREAK REPAIR 162 1.68e-02 0.109000 1.80e-01
REACTOME FLT3 SIGNALING IN DISEASE 28 1.69e-02 0.261000 1.80e-01
REACTOME PROGRAMMED CELL DEATH 204 1.70e-02 0.097000 1.80e-01
REACTOME DNA REPAIR 321 1.72e-02 0.077400 1.80e-01
REACTOME MISMATCH REPAIR 15 1.73e-02 0.355000 1.80e-01
REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 22 1.75e-02 0.293000 1.80e-01
REACTOME RECYCLING OF BILE ACIDS AND SALTS 18 1.76e-02 -0.323000 1.80e-01
REACTOME FASL CD95L SIGNALING 5 1.76e-02 0.613000 1.80e-01
REACTOME RHO GTPASES ACTIVATE FORMINS 136 1.77e-02 0.118000 1.80e-01
REACTOME TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS 43 1.77e-02 0.209000 1.80e-01
REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL 129 1.78e-02 0.121000 1.81e-01
REACTOME TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT 18 1.81e-02 0.322000 1.81e-01
REACTOME CROSSLINKING OF COLLAGEN FIBRILS 16 1.81e-02 -0.341000 1.81e-01
REACTOME ACYL CHAIN REMODELING OF DAG AND TAG 5 1.82e-02 -0.610000 1.81e-01
REACTOME DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING 61 1.83e-02 0.175000 1.81e-01
REACTOME REGULATION OF RAS BY GAPS 66 1.92e-02 0.167000 1.89e-01
REACTOME NCAM1 INTERACTIONS 41 1.93e-02 -0.211000 1.89e-01
REACTOME TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER 76 1.95e-02 0.155000 1.89e-01
REACTOME G1 S DNA DAMAGE CHECKPOINTS 67 1.98e-02 0.165000 1.91e-01
REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 73 2.01e-02 0.157000 1.93e-01
REACTOME MAPK6 MAPK4 SIGNALING 91 2.07e-02 0.140000 1.96e-01
REACTOME NEDDYLATION 235 2.09e-02 0.087500 1.96e-01
REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS 418 2.09e-02 0.065800 1.96e-01
REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM 50 2.09e-02 -0.189000 1.96e-01
REACTOME MUSCLE CONTRACTION 197 2.10e-02 -0.095400 1.96e-01
REACTOME TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX 10 2.17e-02 0.419000 2.01e-01
REACTOME HATS ACETYLATE HISTONES 129 2.19e-02 0.117000 2.01e-01
REACTOME TRANSPORT OF FATTY ACIDS 8 2.20e-02 -0.468000 2.01e-01
REACTOME ASPARAGINE N LINKED GLYCOSYLATION 299 2.20e-02 0.077000 2.01e-01
REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT 31 2.24e-02 0.237000 2.02e-01
REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES 353 2.25e-02 0.070700 2.02e-01
REACTOME ORC1 REMOVAL FROM CHROMATIN 70 2.26e-02 0.158000 2.02e-01
REACTOME GLYCOSAMINOGLYCAN METABOLISM 118 2.27e-02 -0.121000 2.02e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION 89 2.31e-02 0.139000 2.05e-01
REACTOME ANTIGEN PROCESSING CROSS PRESENTATION 98 2.33e-02 0.133000 2.06e-01
REACTOME BUDDING AND MATURATION OF HIV VIRION 28 2.36e-02 0.247000 2.07e-01
REACTOME FLT3 SIGNALING BY CBL MUTANTS 7 2.38e-02 0.493000 2.08e-01
REACTOME LGI ADAM INTERACTIONS 14 2.43e-02 0.348000 2.10e-01
REACTOME INTERLEUKIN 1 FAMILY SIGNALING 146 2.43e-02 0.108000 2.10e-01
REACTOME EFFECTS OF PIP2 HYDROLYSIS 26 2.45e-02 -0.255000 2.10e-01
REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION 35 2.46e-02 0.220000 2.10e-01
REACTOME CYCLIN D ASSOCIATED EVENTS IN G1 46 2.48e-02 0.191000 2.11e-01
REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS 15 2.51e-02 -0.334000 2.11e-01
REACTOME ADHERENS JUNCTIONS INTERACTIONS 33 2.52e-02 -0.225000 2.11e-01
REACTOME CELL JUNCTION ORGANIZATION 89 2.52e-02 -0.137000 2.11e-01
REACTOME NECTIN NECL TRANS HETERODIMERIZATION 7 2.53e-02 -0.488000 2.11e-01
REACTOME METABOLISM OF LIPIDS 709 2.54e-02 -0.049300 2.11e-01
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION 138 2.60e-02 0.110000 2.14e-01
REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH 62 2.61e-02 -0.163000 2.14e-01
REACTOME MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION 15 2.62e-02 0.331000 2.14e-01
REACTOME REPRODUCTION 136 2.64e-02 0.110000 2.14e-01
REACTOME STAT5 ACTIVATION 7 2.65e-02 0.484000 2.14e-01
REACTOME CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY 84 2.66e-02 0.140000 2.14e-01
REACTOME RESPIRATORY ELECTRON TRANSPORT 90 2.68e-02 0.135000 2.14e-01
REACTOME TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA 36 2.69e-02 0.213000 2.14e-01
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION 361 2.70e-02 0.067800 2.14e-01
REACTOME COLLAGEN FORMATION 88 2.74e-02 -0.136000 2.16e-01
REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS 60 2.77e-02 0.164000 2.18e-01
REACTOME OXIDATIVE STRESS INDUCED SENESCENCE 118 2.81e-02 0.117000 2.19e-01
REACTOME CELL CELL JUNCTION ORGANIZATION 64 2.81e-02 -0.159000 2.19e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION 102 2.87e-02 0.125000 2.22e-01
REACTOME HDR THROUGH HOMOLOGOUS RECOMBINATION HRR 66 2.92e-02 0.155000 2.24e-01
REACTOME TRNA PROCESSING 105 2.93e-02 0.123000 2.24e-01
REACTOME DEGRADATION OF GLI1 BY THE PROTEASOME 59 2.94e-02 0.164000 2.24e-01
REACTOME CELLULAR RESPONSE TO HYPOXIA 74 2.98e-02 0.146000 2.26e-01
REACTOME TRANSCRIPTIONAL REGULATION BY TP53 351 3.06e-02 0.067200 2.32e-01
REACTOME APOPTOSIS 173 3.09e-02 0.095100 2.32e-01
REACTOME DIGESTION AND ABSORPTION 22 3.11e-02 -0.266000 2.32e-01
REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3 679 3.12e-02 0.048500 2.32e-01
REACTOME ASSEMBLY OF THE HIV VIRION 16 3.12e-02 0.311000 2.32e-01
REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX 9 3.21e-02 0.412000 2.37e-01
REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS 188 3.21e-02 0.090600 2.37e-01
REACTOME INTERLEUKIN 1 SIGNALING 110 3.23e-02 0.118000 2.37e-01
REACTOME NOD1 2 SIGNALING PATHWAY 33 3.29e-02 0.215000 2.39e-01
REACTOME RNA POLYMERASE II TRANSCRIBES SNRNA GENES 77 3.31e-02 0.140000 2.39e-01
REACTOME KEAP1 NFE2L2 PATHWAY 104 3.31e-02 0.121000 2.39e-01
REACTOME NS1 MEDIATED EFFECTS ON HOST PATHWAYS 41 3.32e-02 0.192000 2.39e-01
REACTOME TRANSLESION SYNTHESIS BY POLH 19 3.35e-02 0.282000 2.41e-01
REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC 28 3.38e-02 0.232000 2.41e-01
REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS 55 3.40e-02 -0.165000 2.41e-01
REACTOME ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES 59 3.40e-02 -0.160000 2.41e-01
REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR 79 3.54e-02 0.137000 2.49e-01
REACTOME THYROXINE BIOSYNTHESIS 10 3.56e-02 -0.384000 2.50e-01
REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA 28 3.63e-02 0.229000 2.53e-01
REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS 39 3.64e-02 -0.194000 2.53e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION TERMINATION 30 3.66e-02 0.220000 2.54e-01
REACTOME STABILIZATION OF P53 56 3.69e-02 0.161000 2.54e-01
REACTOME PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR 21 3.70e-02 0.263000 2.54e-01
REACTOME REGULATION OF SIGNALING BY CBL 22 3.71e-02 0.257000 2.54e-01
REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION 84 3.82e-02 0.131000 2.60e-01
REACTOME DEUBIQUITINATION 260 3.83e-02 0.074600 2.60e-01
REACTOME INTERLEUKIN 12 SIGNALING 43 3.85e-02 0.182000 2.60e-01
REACTOME SENSORY PERCEPTION OF SALTY TASTE 6 3.88e-02 -0.487000 2.61e-01
REACTOME SUMOYLATION 179 3.98e-02 0.089100 2.66e-01
REACTOME TIE2 SIGNALING 18 3.99e-02 0.280000 2.66e-01
REACTOME NUCLEAR IMPORT OF REV PROTEIN 34 4.03e-02 0.203000 2.68e-01
REACTOME PTK6 PROMOTES HIF1A STABILIZATION 6 4.11e-02 0.482000 2.71e-01
REACTOME SIGNALING BY PDGFR IN DISEASE 20 4.11e-02 0.264000 2.71e-01
REACTOME REGULATED NECROSIS 57 4.12e-02 0.156000 2.71e-01
REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING 26 4.16e-02 0.231000 2.72e-01
REACTOME HOST INTERACTIONS OF HIV FACTORS 127 4.18e-02 0.105000 2.72e-01
REACTOME SIGNALING BY SCF KIT 42 4.20e-02 0.181000 2.72e-01
REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A 26 4.22e-02 0.230000 2.72e-01
REACTOME ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS 27 4.23e-02 0.226000 2.72e-01
REACTOME LATE ENDOSOMAL MICROAUTOPHAGY 33 4.24e-02 0.204000 2.72e-01
REACTOME THE NLRP3 INFLAMMASOME 16 4.28e-02 0.293000 2.73e-01
REACTOME CRMPS IN SEMA3A SIGNALING 15 4.30e-02 -0.302000 2.74e-01
REACTOME PREVENTION OF PHAGOSOMAL LYSOSOMAL FUSION 9 4.32e-02 0.389000 2.74e-01
REACTOME POLYMERASE SWITCHING 13 4.46e-02 0.322000 2.82e-01
REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS 15 4.50e-02 -0.299000 2.83e-01
REACTOME PROTEIN LOCALIZATION 153 4.52e-02 0.093800 2.84e-01
REACTOME FLT3 SIGNALING THROUGH SRC FAMILY KINASES 6 4.55e-02 0.471000 2.84e-01
REACTOME SUMOYLATION OF SUMOYLATION PROTEINS 35 4.58e-02 0.195000 2.84e-01
REACTOME TRNA PROCESSING IN THE NUCLEUS 58 4.59e-02 0.152000 2.84e-01
REACTOME IRAK1 RECRUITS IKK COMPLEX 12 4.60e-02 0.333000 2.84e-01
REACTOME OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS 8 4.65e-02 -0.406000 2.84e-01
REACTOME RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA 7 4.67e-02 0.434000 2.84e-01
REACTOME INTERLEUKIN 7 SIGNALING 31 4.67e-02 0.206000 2.84e-01
REACTOME MYD88 INDEPENDENT TLR4 CASCADE 103 4.68e-02 0.113000 2.84e-01
REACTOME PROCESSING OF INTRONLESS PRE MRNAS 19 4.69e-02 0.263000 2.84e-01
REACTOME INDUCTION OF CELL CELL FUSION 12 4.72e-02 -0.331000 2.84e-01
REACTOME VIRAL MESSENGER RNA SYNTHESIS 44 4.73e-02 0.173000 2.84e-01
REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION 60 4.74e-02 0.148000 2.84e-01
REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX 31 4.80e-02 0.205000 2.87e-01
REACTOME DAP12 SIGNALING 27 4.84e-02 0.219000 2.88e-01
REACTOME DUAL INCISION IN TC NER 63 4.88e-02 0.144000 2.89e-01
REACTOME GENE SILENCING BY RNA 133 4.94e-02 0.098700 2.92e-01
REACTOME INFLAMMASOMES 21 4.99e-02 0.247000 2.94e-01
REACTOME MELANIN BIOSYNTHESIS 5 5.08e-02 -0.504000 2.98e-01
REACTOME REGULATION OF SIGNALING BY NODAL 9 5.13e-02 0.375000 3.00e-01
REACTOME TELOMERE MAINTENANCE 106 5.19e-02 0.109000 3.02e-01
REACTOME PRC2 METHYLATES HISTONES AND DNA 65 5.26e-02 0.139000 3.05e-01
REACTOME DISEASES OF MISMATCH REPAIR MMR 5 5.28e-02 0.500000 3.05e-01
REACTOME ESTABLISHMENT OF SISTER CHROMATID COHESION 9 5.32e-02 0.372000 3.05e-01
REACTOME DNA DAMAGE REVERSAL 8 5.33e-02 -0.395000 3.05e-01
REACTOME SUMOYLATION OF UBIQUITINYLATION PROTEINS 39 5.33e-02 0.179000 3.05e-01
REACTOME SUMOYLATION OF RNA BINDING PROTEINS 47 5.36e-02 0.163000 3.05e-01
REACTOME TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS 29 5.40e-02 0.207000 3.07e-01
REACTOME HEDGEHOG LIGAND BIOGENESIS 64 5.47e-02 0.139000 3.10e-01
REACTOME INTEGRIN SIGNALING 27 5.51e-02 -0.213000 3.11e-01
REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 54 5.58e-02 0.150000 3.13e-01
REACTOME MATURATION OF SARS COV 2 NUCLEOPROTEIN 15 5.65e-02 0.284000 3.13e-01
REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY 5 5.69e-02 0.492000 3.13e-01
REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION 13 5.70e-02 -0.305000 3.13e-01
REACTOME SIGNALING BY NOTCH4 80 5.72e-02 0.123000 3.13e-01
REACTOME SODIUM PROTON EXCHANGERS 7 5.73e-02 -0.415000 3.13e-01
REACTOME SIGNALING BY CSF3 G CSF 30 5.73e-02 0.201000 3.13e-01
REACTOME CARDIAC CONDUCTION 125 5.73e-02 -0.098400 3.13e-01
REACTOME PLASMA LIPOPROTEIN REMODELING 33 5.74e-02 -0.191000 3.13e-01
REACTOME COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING 38 5.75e-02 0.178000 3.13e-01
REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES 18 5.79e-02 -0.258000 3.13e-01
REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION 296 5.81e-02 0.064000 3.13e-01
REACTOME LAMININ INTERACTIONS 28 5.81e-02 -0.207000 3.13e-01
REACTOME VLDL CLEARANCE 6 5.84e-02 0.446000 3.13e-01
REACTOME PERK REGULATES GENE EXPRESSION 31 5.85e-02 0.196000 3.13e-01
REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION 20 5.86e-02 0.244000 3.13e-01
REACTOME UCH PROTEINASES 99 5.89e-02 0.110000 3.14e-01
REACTOME LAGGING STRAND SYNTHESIS 19 5.96e-02 0.250000 3.16e-01
REACTOME INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS 37 5.98e-02 0.179000 3.16e-01
REACTOME DNA REPLICATION INITIATION 7 5.99e-02 0.411000 3.16e-01
REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS 18 6.02e-02 -0.256000 3.17e-01
REACTOME CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION 24 6.06e-02 0.221000 3.17e-01
REACTOME UNFOLDED PROTEIN RESPONSE UPR 88 6.06e-02 0.116000 3.17e-01
REACTOME DNA DAMAGE RECOGNITION IN GG NER 36 6.08e-02 0.181000 3.17e-01
REACTOME REGULATION OF BACH1 ACTIVITY 11 6.16e-02 0.326000 3.20e-01
REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS 33 6.19e-02 0.188000 3.20e-01
REACTOME HDL CLEARANCE 5 6.19e-02 -0.482000 3.20e-01
REACTOME DEGRADATION OF DVL 56 6.32e-02 0.144000 3.25e-01
REACTOME NEGATIVE REGULATION OF MAPK PATHWAY 41 6.41e-02 0.167000 3.29e-01
REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS 83 6.44e-02 0.117000 3.30e-01
REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES 38 6.50e-02 -0.173000 3.31e-01
REACTOME PROTEIN FOLDING 96 6.51e-02 0.109000 3.31e-01
REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER 18 6.52e-02 0.251000 3.31e-01
REACTOME HDR THROUGH SINGLE STRAND ANNEALING SSA 37 6.60e-02 0.175000 3.32e-01
REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN 32 6.63e-02 0.188000 3.32e-01
REACTOME METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES 33 6.64e-02 -0.185000 3.32e-01
REACTOME POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION 27 6.64e-02 0.204000 3.32e-01
REACTOME TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS 55 6.65e-02 0.143000 3.32e-01
REACTOME SIGNALING BY PTK6 54 6.71e-02 0.144000 3.32e-01
REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY 72 6.71e-02 0.125000 3.32e-01
REACTOME METABOLISM OF STEROIDS 150 6.74e-02 -0.086500 3.32e-01
REACTOME INTERLEUKIN 21 SIGNALING 9 6.77e-02 0.352000 3.32e-01
REACTOME HYALURONAN BIOSYNTHESIS AND EXPORT 5 6.78e-02 -0.472000 3.32e-01
REACTOME MET PROMOTES CELL MOTILITY 41 6.79e-02 -0.165000 3.32e-01
REACTOME G ALPHA Q SIGNALLING EVENTS 206 6.79e-02 -0.073800 3.32e-01
REACTOME VXPX CARGO TARGETING TO CILIUM 20 6.84e-02 -0.235000 3.33e-01
REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE 93 6.85e-02 0.109000 3.33e-01
REACTOME NRAGE SIGNALS DEATH THROUGH JNK 53 6.95e-02 -0.144000 3.36e-01
REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B 24 6.97e-02 0.214000 3.36e-01
REACTOME MATURATION OF SARS COV 1 SPIKE PROTEIN 5 6.98e-02 0.468000 3.36e-01
REACTOME MET INTERACTS WITH TNS PROTEINS 5 7.00e-02 -0.468000 3.36e-01
REACTOME ELASTIC FIBRE FORMATION 44 7.08e-02 -0.157000 3.38e-01
REACTOME HEDGEHOG ON STATE 85 7.08e-02 0.113000 3.38e-01
REACTOME CHROMATIN MODIFYING ENZYMES 252 7.14e-02 0.065900 3.40e-01
REACTOME ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS 17 7.17e-02 0.252000 3.40e-01
REACTOME TRIGLYCERIDE BIOSYNTHESIS 12 7.22e-02 -0.300000 3.41e-01
REACTOME POLO LIKE KINASE MEDIATED EVENTS 16 7.25e-02 0.259000 3.41e-01
REACTOME FANCONI ANEMIA PATHWAY 35 7.26e-02 0.175000 3.41e-01
REACTOME CHL1 INTERACTIONS 9 7.28e-02 -0.345000 3.41e-01
REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 98 7.32e-02 0.105000 3.42e-01
REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS 12 7.54e-02 -0.296000 3.51e-01
REACTOME REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION 84 7.54e-02 0.112000 3.51e-01
REACTOME RHO GTPASES ACTIVATE PKNS 86 7.68e-02 0.110000 3.55e-01
REACTOME COLLAGEN DEGRADATION 61 7.70e-02 -0.131000 3.55e-01
REACTOME EXTENSION OF TELOMERES 49 7.70e-02 0.146000 3.55e-01
REACTOME ANDROGEN BIOSYNTHESIS 11 7.80e-02 -0.307000 3.58e-01
REACTOME DISEASES OF PROGRAMMED CELL DEATH 96 7.81e-02 0.104000 3.58e-01
REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING 34 7.82e-02 0.175000 3.58e-01
REACTOME RORA ACTIVATES GENE EXPRESSION 17 7.85e-02 -0.246000 3.58e-01
REACTOME INTERLEUKIN 2 SIGNALING 11 7.90e-02 0.306000 3.59e-01
REACTOME DRUG MEDIATED INHIBITION OF CDK4 CDK6 ACTIVITY 5 8.00e-02 0.452000 3.63e-01
REACTOME DOWNREGULATION OF ERBB2 SIGNALING 29 8.03e-02 0.188000 3.63e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX3 94 8.10e-02 0.104000 3.65e-01
REACTOME MITOCHONDRIAL PROTEIN IMPORT 58 8.19e-02 0.132000 3.67e-01
REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS 5 8.25e-02 -0.448000 3.67e-01
REACTOME HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS 9 8.28e-02 0.334000 3.67e-01
REACTOME INTERLEUKIN 18 SIGNALING 8 8.29e-02 0.354000 3.67e-01
REACTOME DISEASES OF MITOTIC CELL CYCLE 37 8.30e-02 0.165000 3.67e-01
REACTOME SIGNALING BY FLT3 ITD AND TKD MUTANTS 16 8.30e-02 0.250000 3.67e-01
REACTOME TOLL LIKE RECEPTOR 9 TLR9 CASCADE 100 8.30e-02 0.100000 3.67e-01
REACTOME TLR3 MEDIATED TICAM1 DEPENDENT PROGRAMMED CELL DEATH 6 8.33e-02 0.408000 3.67e-01
REACTOME REGULATION OF IFNA IFNB SIGNALING 23 8.33e-02 0.209000 3.67e-01
REACTOME TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA 17 8.37e-02 0.242000 3.67e-01
REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE 24 8.42e-02 0.204000 3.67e-01
REACTOME DEGRADATION OF AXIN 54 8.42e-02 0.136000 3.67e-01
REACTOME DIGESTION 17 8.44e-02 -0.242000 3.67e-01
REACTOME UB SPECIFIC PROCESSING PROTEASES 187 8.50e-02 0.073000 3.67e-01
REACTOME CITRIC ACID CYCLE TCA CYCLE 21 8.51e-02 0.217000 3.67e-01
REACTOME RESOLUTION OF ABASIC SITES AP SITES 38 8.51e-02 0.161000 3.67e-01
REACTOME COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM 21 8.52e-02 -0.217000 3.67e-01
REACTOME FOLDING OF ACTIN BY CCT TRIC 10 8.76e-02 0.312000 3.75e-01
REACTOME CLEC7A INFLAMMASOME PATHWAY 6 8.80e-02 0.402000 3.75e-01
REACTOME O LINKED GLYCOSYLATION OF MUCINS 61 8.83e-02 -0.126000 3.75e-01
REACTOME INTERFERON GAMMA SIGNALING 88 8.84e-02 0.105000 3.75e-01
REACTOME CONDENSATION OF PROPHASE CHROMOSOMES 66 8.84e-02 0.121000 3.75e-01
REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3 59 8.85e-02 0.128000 3.75e-01
REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION 13 8.86e-02 0.273000 3.75e-01
REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS 18 8.89e-02 0.232000 3.75e-01
REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION 10 8.90e-02 0.311000 3.75e-01
REACTOME COMMON PATHWAY OF FIBRIN CLOT FORMATION 21 9.01e-02 -0.214000 3.78e-01
REACTOME MET ACTIVATES PTK2 SIGNALING 30 9.03e-02 -0.179000 3.78e-01
REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES 80 9.08e-02 0.109000 3.79e-01
REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR 24 9.13e-02 0.199000 3.80e-01
REACTOME RAB GERANYLGERANYLATION 57 9.26e-02 0.129000 3.85e-01
REACTOME INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING 103 9.28e-02 0.095900 3.85e-01
REACTOME RIPK1 MEDIATED REGULATED NECROSIS 30 9.30e-02 0.177000 3.85e-01
REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI 26 9.37e-02 -0.190000 3.87e-01
REACTOMEMATURATION OF SARS COV 1 NUCLEOPROTEIN 11 9.44e-02 0.291000 3.88e-01
REACTOME OTHER SEMAPHORIN INTERACTIONS 18 9.46e-02 -0.228000 3.88e-01
REACTOME NONHOMOLOGOUS END JOINING NHEJ 64 9.46e-02 0.121000 3.88e-01
REACTOME NUCLEAR PORE COMPLEX NPC DISASSEMBLY 36 9.55e-02 0.161000 3.90e-01
REACTOME RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY 14 9.65e-02 0.257000 3.93e-01
REACTOME SIGNALING BY CSF1 M CSF IN MYELOID CELLS 30 9.66e-02 0.175000 3.93e-01
REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS 28 9.70e-02 0.181000 3.93e-01
REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY 25 9.79e-02 0.191000 3.95e-01
REACTOME PROCESSING AND ACTIVATION OF SUMO 10 9.80e-02 0.302000 3.95e-01
REACTOME TELOMERE C STRAND LAGGING STRAND SYNTHESIS 33 9.83e-02 0.166000 3.96e-01
REACTOME REGULATION OF LIPID METABOLISM BY PPARALPHA 115 9.92e-02 -0.089000 3.98e-01
REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION 62 9.95e-02 0.121000 3.99e-01
REACTOME TRIF MEDIATED PROGRAMMED CELL DEATH 9 1.00e-01 0.317000 4.00e-01
REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE 16 1.01e-01 0.237000 4.02e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS 14 1.01e-01 -0.253000 4.03e-01
REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS 63 1.02e-01 0.119000 4.03e-01
REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND 14 1.02e-01 0.253000 4.03e-01
REACTOME INTERLEUKIN 2 FAMILY SIGNALING 40 1.03e-01 0.149000 4.04e-01
REACTOME SYNTHESIS OF 15 EICOSATETRAENOIC ACID DERIVATIVES 6 1.03e-01 -0.385000 4.04e-01
REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES 101 1.03e-01 -0.093800 4.04e-01
REACTOME SENSORY PERCEPTION OF TASTE 47 1.03e-01 -0.137000 4.04e-01
REACTOME COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES 65 1.04e-01 -0.117000 4.05e-01
REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR 11 1.04e-01 0.283000 4.07e-01
REACTOME RHOB GTPASE CYCLE 67 1.05e-01 -0.115000 4.07e-01
REACTOME SIGNALING BY ALK IN CANCER 53 1.05e-01 0.129000 4.08e-01
REACTOME TRIGLYCERIDE METABOLISM 35 1.05e-01 -0.158000 4.08e-01
REACTOME COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING 32 1.06e-01 0.165000 4.08e-01
REACTOME CELL CELL COMMUNICATION 126 1.06e-01 -0.083400 4.08e-01
REACTOME FORMATION OF LATERAL PLATE MESODERM 5 1.06e-01 0.417000 4.08e-01
REACTOME G2 PHASE 5 1.07e-01 0.417000 4.09e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH CDC42 19 1.07e-01 0.213000 4.09e-01
REACTOME BETA OXIDATION OF PRISTANOYL COA 9 1.07e-01 -0.310000 4.09e-01
REACTOME ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY 10 1.08e-01 0.294000 4.09e-01
REACTOME APOPTOTIC FACTOR MEDIATED RESPONSE 19 1.08e-01 0.213000 4.09e-01
REACTOME RHOC GTPASE CYCLE 71 1.08e-01 -0.110000 4.09e-01
REACTOME G PROTEIN ACTIVATION 24 1.08e-01 0.190000 4.09e-01
REACTOME KETONE BODY METABOLISM 9 1.09e-01 -0.309000 4.10e-01
REACTOME SCAVENGING BY CLASS F RECEPTORS 6 1.09e-01 0.378000 4.10e-01
REACTOME CLATHRIN MEDIATED ENDOCYTOSIS 139 1.09e-01 0.078700 4.10e-01
REACTOME INTEGRIN CELL SURFACE INTERACTIONS 83 1.10e-01 -0.102000 4.10e-01
REACTOME SEMAPHORIN INTERACTIONS 61 1.10e-01 -0.118000 4.10e-01
REACTOME CELLULAR RESPONSE TO HEAT STRESS 99 1.10e-01 0.093000 4.10e-01
REACTOME SIGNALING BY ERBB2 50 1.11e-01 0.130000 4.12e-01
REACTOME DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15 8 1.11e-01 -0.325000 4.12e-01
REACTOME MITOCHONDRIAL UNCOUPLING 5 1.12e-01 0.411000 4.12e-01
REACTOME METABOLISM OF POLYAMINES 56 1.12e-01 0.123000 4.12e-01
REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS 23 1.12e-01 -0.191000 4.12e-01
REACTOME POTASSIUM CHANNELS 102 1.12e-01 -0.091000 4.12e-01
REACTOME REPRESSION OF WNT TARGET GENES 14 1.12e-01 -0.245000 4.12e-01
REACTOME RHOBTB GTPASE CYCLE 34 1.12e-01 0.157000 4.12e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE 74 1.13e-01 -0.107000 4.13e-01
REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING 12 1.13e-01 -0.264000 4.13e-01
REACTOME COSTIMULATION BY THE CD28 FAMILY 64 1.14e-01 0.114000 4.14e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS 9 1.15e-01 -0.304000 4.16e-01
REACTOME COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC 98 1.16e-01 0.091900 4.19e-01
REACTOME SIGNALING BY FGFR4 40 1.16e-01 0.144000 4.19e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION 36 1.16e-01 0.151000 4.19e-01
REACTOME DOWNREGULATION OF ERBB4 SIGNALING 9 1.17e-01 0.302000 4.19e-01
REACTOME DNA METHYLATION 58 1.17e-01 0.119000 4.19e-01
REACTOME POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE 25 1.17e-01 0.181000 4.20e-01
REACTOME CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND 16 1.18e-01 0.226000 4.20e-01
REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE 30 1.18e-01 -0.165000 4.20e-01
REACTOME DISEASES OF DNA REPAIR 51 1.19e-01 0.126000 4.22e-01
REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC 26 1.19e-01 0.177000 4.22e-01
REACTOME PI 3K CASCADE FGFR4 19 1.19e-01 0.207000 4.22e-01
REACTOME ER TO GOLGI ANTEROGRADE TRANSPORT 152 1.19e-01 0.073200 4.22e-01
REACTOME STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS 10 1.20e-01 0.284000 4.25e-01
REACTOME SIGNALING BY EGFR IN CANCER 25 1.21e-01 0.179000 4.25e-01
REACTOME P75NTR SIGNALS VIA NF KB 15 1.22e-01 0.231000 4.28e-01
REACTOME HIV TRANSCRIPTION INITIATION 43 1.22e-01 0.136000 4.29e-01
REACTOME COLLAGEN CHAIN TRIMERIZATION 42 1.23e-01 -0.138000 4.29e-01
REACTOME HDACS DEACETYLATE HISTONES 85 1.24e-01 0.096600 4.32e-01
REACTOME SIGNALING BY NOTCH 234 1.24e-01 0.058400 4.32e-01
REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER 77 1.24e-01 0.101000 4.32e-01
REACTOME SIGNALING BY NUCLEAR RECEPTORS 283 1.25e-01 0.052900 4.35e-01
REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING 25 1.26e-01 0.177000 4.36e-01
REACTOME FRS MEDIATED FGFR4 SIGNALING 21 1.27e-01 0.192000 4.40e-01
REACTOME DIGESTION OF DIETARY CARBOHYDRATE 6 1.28e-01 -0.359000 4.40e-01
REACTOME SUPPRESSION OF PHAGOSOMAL MATURATION 13 1.28e-01 0.244000 4.41e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM 38 1.29e-01 -0.142000 4.41e-01
REACTOME EXTRA NUCLEAR ESTROGEN SIGNALING 74 1.29e-01 0.102000 4.41e-01
REACTOME ESR MEDIATED SIGNALING 210 1.29e-01 0.060800 4.41e-01
REACTOME SYNTHESIS OF KETONE BODIES 8 1.29e-01 -0.310000 4.41e-01
REACTOME RMTS METHYLATE HISTONE ARGININES 72 1.30e-01 0.103000 4.43e-01
REACTOME FCGR ACTIVATION 11 1.30e-01 0.263000 4.43e-01
REACTOME ONCOGENE INDUCED SENESCENCE 35 1.31e-01 0.148000 4.43e-01
REACTOME PD 1 SIGNALING 21 1.32e-01 0.190000 4.47e-01
REACTOME PHOSPHORYLATION OF THE APC C 20 1.33e-01 0.194000 4.47e-01
REACTOME ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE 9 1.33e-01 0.289000 4.47e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR4 26 1.33e-01 0.170000 4.47e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX2 117 1.33e-01 0.080300 4.48e-01
REACTOME DEFECTIVE CHST6 CAUSES MCDC1 8 1.34e-01 -0.306000 4.48e-01
REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX 13 1.34e-01 0.240000 4.48e-01
REACTOME SCAVENGING BY CLASS A RECEPTORS 19 1.35e-01 0.198000 4.49e-01
REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS 68 1.35e-01 0.105000 4.49e-01
REACTOME CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS 100 1.35e-01 0.086400 4.49e-01
REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS 6 1.35e-01 -0.352000 4.49e-01
REACTOME SEROTONIN RECEPTORS 11 1.36e-01 -0.259000 4.51e-01
REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING 30 1.37e-01 0.157000 4.51e-01
REACTOME ARACHIDONIC ACID METABOLISM 57 1.37e-01 -0.114000 4.51e-01
REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES 27 1.38e-01 0.165000 4.54e-01
REACTOME DCC MEDIATED ATTRACTIVE SIGNALING 14 1.39e-01 -0.228000 4.57e-01
REACTOME CARNITINE METABOLISM 13 1.40e-01 -0.237000 4.57e-01
REACTOME COBALAMIN CBL METABOLISM 7 1.40e-01 -0.322000 4.59e-01
REACTOME ANCHORING FIBRIL FORMATION 13 1.41e-01 -0.236000 4.61e-01
REACTOME OPSINS 7 1.42e-01 -0.320000 4.61e-01
REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS 14 1.42e-01 0.227000 4.61e-01
REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION 31 1.42e-01 0.152000 4.61e-01
REACTOME CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS 19 1.42e-01 0.194000 4.61e-01
REACTOME MRNA SPLICING MINOR PATHWAY 49 1.43e-01 0.121000 4.62e-01
REACTOME MITOTIC TELOPHASE CYTOKINESIS 11 1.44e-01 0.254000 4.66e-01
REACTOME DNA DOUBLE STRAND BREAK RESPONSE 74 1.46e-01 0.097700 4.70e-01
REACTOME SYNDECAN INTERACTIONS 26 1.46e-01 -0.165000 4.70e-01
REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS 13 1.47e-01 -0.232000 4.71e-01
REACTOME NEUROTRANSMITTER RELEASE CYCLE 48 1.47e-01 0.121000 4.71e-01
REACTOME SYNTHESIS OF PI 5 1.48e-01 -0.374000 4.73e-01
REACTOME CD28 CO STIMULATION 32 1.49e-01 0.147000 4.75e-01
REACTOME MEMBRANE TRAFFICKING 603 1.49e-01 0.034400 4.76e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION 27 1.50e-01 0.160000 4.77e-01
REACTOME PI 3K CASCADE FGFR3 17 1.51e-01 0.201000 4.77e-01
REACTOME RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS 9 1.51e-01 0.277000 4.77e-01
REACTOME ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION 16 1.53e-01 0.206000 4.83e-01
REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS 21 1.53e-01 0.180000 4.83e-01
REACTOME CD28 DEPENDENT VAV1 PATHWAY 11 1.54e-01 0.248000 4.83e-01
REACTOME INTERLEUKIN 1 PROCESSING 9 1.54e-01 0.274000 4.84e-01
REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 122 1.54e-01 -0.074600 4.84e-01
REACTOME CELLULAR HEXOSE TRANSPORT 21 1.55e-01 -0.179000 4.85e-01
REACTOME ACTIVATION OF TRKA RECEPTORS 6 1.57e-01 -0.334000 4.87e-01
REACTOME NGF STIMULATED TRANSCRIPTION 38 1.57e-01 0.133000 4.87e-01
REACTOME RUNX3 REGULATES BCL2L11 BIM TRANSCRIPTION 5 1.57e-01 -0.366000 4.87e-01
REACTOME REGULATION OF TP53 ACTIVITY 156 1.58e-01 0.065600 4.89e-01
REACTOME SYNTHESIS OF PG 8 1.58e-01 0.288000 4.90e-01
REACTOME RAS SIGNALING DOWNSTREAM OF NF1 LOSS OF FUNCTION VARIANTS 7 1.60e-01 0.307000 4.93e-01
REACTOME SIGNALING BY FGFR2 72 1.60e-01 0.095700 4.93e-01
REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY 51 1.60e-01 0.114000 4.93e-01
REACTOME SIGNALING BY FLT3 FUSION PROTEINS 19 1.61e-01 0.186000 4.93e-01
REACTOME FRS MEDIATED FGFR3 SIGNALING 19 1.61e-01 0.186000 4.93e-01
REACTOME SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL 8 1.62e-01 -0.286000 4.96e-01
REACTOME PTK6 EXPRESSION 5 1.63e-01 0.361000 4.96e-01
REACTOME EPHA MEDIATED GROWTH CONE COLLAPSE 29 1.63e-01 -0.150000 4.96e-01
REACTOME UPTAKE OF DIETARY COBALAMINS INTO ENTEROCYTES 9 1.63e-01 -0.268000 4.97e-01
REACTOME IRS MEDIATED SIGNALLING 47 1.65e-01 0.117000 4.99e-01
REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE 11 1.65e-01 -0.242000 4.99e-01
REACTOME BINDING OF TCF LEF CTNNB1 TO TARGET GENE PROMOTERS 8 1.65e-01 -0.283000 4.99e-01
REACTOME INTEGRATION OF ENERGY METABOLISM 105 1.66e-01 -0.078300 4.99e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR3 24 1.66e-01 0.163000 4.99e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH METHYLATION 19 1.66e-01 0.184000 4.99e-01
REACTOME SHC MEDIATED CASCADE FGFR4 19 1.68e-01 0.183000 5.05e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST 14 1.69e-01 0.212000 5.06e-01
REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING 28 1.69e-01 0.150000 5.06e-01
REACTOME TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS 26 1.70e-01 0.156000 5.06e-01
REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS 16 1.70e-01 0.198000 5.06e-01
REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL 12 1.70e-01 0.229000 5.06e-01
REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION 11 1.70e-01 0.239000 5.07e-01
REACTOME GLUCAGON TYPE LIGAND RECEPTORS 32 1.71e-01 0.140000 5.07e-01
REACTOME NETRIN 1 SIGNALING 49 1.71e-01 -0.113000 5.07e-01
REACTOME INACTIVATION OF CSF3 G CSF SIGNALING 25 1.71e-01 0.158000 5.07e-01
REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS 16 1.72e-01 -0.197000 5.07e-01
REACTOME GLYCOLYSIS 70 1.73e-01 0.094200 5.10e-01
REACTOME VESICLE MEDIATED TRANSPORT 642 1.73e-01 0.031500 5.10e-01
REACTOME TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY 16 1.74e-01 0.196000 5.11e-01
REACTOME METABOLISM OF AMINE DERIVED HORMONES 17 1.75e-01 -0.190000 5.13e-01
REACTOME CIPROFLOXACIN ADME 5 1.76e-01 -0.350000 5.13e-01
REACTOME TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION 5 1.76e-01 0.349000 5.13e-01
REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III 31 1.76e-01 0.140000 5.13e-01
REACTOME SUMOYLATION OF DNA REPLICATION PROTEINS 46 1.76e-01 0.115000 5.13e-01
REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK 111 1.78e-01 0.074000 5.15e-01
REACTOME ACTIVATION OF MATRIX METALLOPROTEINASES 30 1.78e-01 -0.142000 5.15e-01
REACTOME DEFECTIVE GALNT3 CAUSES HFTC 16 1.79e-01 -0.194000 5.15e-01
REACTOME P2Y RECEPTORS 9 1.79e-01 -0.259000 5.15e-01
REACTOME SIGNAL TRANSDUCTION BY L1 20 1.79e-01 -0.174000 5.15e-01
REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R 52 1.79e-01 0.108000 5.15e-01
REACTOME HSF1 ACTIVATION 29 1.80e-01 0.144000 5.16e-01
REACTOME HDR THROUGH MMEJ ALT NHEJ 12 1.80e-01 0.224000 5.16e-01
REACTOME INTESTINAL ABSORPTION 5 1.80e-01 -0.346000 5.16e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION 45 1.81e-01 0.115000 5.16e-01
REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB 5 1.81e-01 0.346000 5.16e-01
REACTOME FOXO MEDIATED TRANSCRIPTION 65 1.81e-01 0.095900 5.16e-01
REACTOME SYNTHESIS OF PIPS AT THE ER MEMBRANE 5 1.82e-01 -0.345000 5.18e-01
REACTOME REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO 10 1.82e-01 -0.244000 5.18e-01
REACTOME PINK1 PRKN MEDIATED MITOPHAGY 22 1.83e-01 0.164000 5.18e-01
REACTOME COMPLEMENT CASCADE 54 1.83e-01 0.105000 5.18e-01
REACTOME PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1 9 1.83e-01 0.256000 5.18e-01
REACTOME SCAVENGING BY CLASS B RECEPTORS 6 1.84e-01 -0.313000 5.20e-01
REACTOME ION TRANSPORT BY P TYPE ATPASES 51 1.84e-01 -0.107000 5.20e-01
REACTOME ASPIRIN ADME 42 1.86e-01 -0.118000 5.22e-01
REACTOME TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE 20 1.86e-01 0.171000 5.22e-01
REACTOME KERATAN SULFATE BIOSYNTHESIS 28 1.86e-01 -0.144000 5.22e-01
REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS 35 1.87e-01 0.129000 5.22e-01
REACTOME METALLOPROTEASE DUBS 36 1.87e-01 0.127000 5.22e-01
REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES 12 1.87e-01 0.220000 5.22e-01
REACTOME PI3K AKT SIGNALING IN CANCER 103 1.89e-01 0.074900 5.26e-01
REACTOME NUCLEOTIDE SALVAGE 21 1.90e-01 0.165000 5.26e-01
REACTOME UPTAKE AND ACTIONS OF BACTERIAL TOXINS 28 1.90e-01 0.143000 5.26e-01
REACTOME REGULATION OF GENE EXPRESSION IN ENDOCRINE COMMITTED NEUROG3 PROGENITOR CELLS 5 1.90e-01 0.338000 5.26e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA 25 1.91e-01 0.151000 5.26e-01
REACTOME HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR IN THE PRESENCE OF LIGAND 55 1.91e-01 0.102000 5.26e-01
REACTOME LIPOPHAGY 9 1.92e-01 0.251000 5.30e-01
REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING 13 1.93e-01 -0.209000 5.30e-01
REACTOME PI3K EVENTS IN ERBB4 SIGNALING 10 1.93e-01 0.238000 5.30e-01
REACTOME VISUAL PHOTOTRANSDUCTION 93 1.94e-01 -0.078000 5.30e-01
REACTOME MAPK FAMILY SIGNALING CASCADES 314 1.94e-01 0.042600 5.30e-01
REACTOME RHOBTB2 GTPASE CYCLE 22 1.94e-01 0.160000 5.30e-01
REACTOME INTERLEUKIN 17 SIGNALING 66 1.95e-01 0.092300 5.30e-01
REACTOME PROSTANOID LIGAND RECEPTORS 9 1.95e-01 0.249000 5.30e-01
REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE 66 1.96e-01 0.092000 5.30e-01
REACTOME AMINE LIGAND BINDING RECEPTORS 40 1.96e-01 -0.118000 5.30e-01
REACTOME SIGNALING BY FGFR3 39 1.96e-01 0.120000 5.30e-01
REACTOME TRANSCRIPTIONAL REGULATION BY E2F6 32 1.97e-01 0.132000 5.30e-01
REACTOME MRNA CAPPING 28 1.97e-01 0.141000 5.30e-01
REACTOME DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE 76 1.98e-01 0.085500 5.30e-01
REACTOME REGULATION OF IFNG SIGNALING 14 1.98e-01 0.199000 5.30e-01
REACTOME ATTENUATION PHASE 27 1.98e-01 0.143000 5.30e-01
REACTOME RHOBTB1 GTPASE CYCLE 22 1.98e-01 0.158000 5.30e-01
REACTOME P75NTR REGULATES AXONOGENESIS 9 1.98e-01 -0.248000 5.30e-01
REACTOME ETHANOL OXIDATION 12 1.99e-01 -0.214000 5.30e-01
REACTOME PHASE 0 RAPID DEPOLARISATION 31 1.99e-01 -0.133000 5.30e-01
REACTOME INTERLEUKIN 36 PATHWAY 7 1.99e-01 -0.280000 5.30e-01
REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX 32 2.00e-01 0.131000 5.32e-01
REACTOME MINERALOCORTICOID BIOSYNTHESIS 6 2.01e-01 -0.302000 5.34e-01
REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS 37 2.02e-01 0.121000 5.35e-01
REACTOME PYRIMIDINE SALVAGE 10 2.02e-01 0.233000 5.35e-01
REACTOME VOLTAGE GATED POTASSIUM CHANNELS 42 2.03e-01 -0.114000 5.36e-01
REACTOME INTERLEUKIN 20 FAMILY SIGNALING 25 2.04e-01 -0.147000 5.38e-01
REACTOME SIGNALING BY ERBB2 IN CANCER 26 2.05e-01 0.144000 5.40e-01
REACTOME PEPTIDE LIGAND BINDING RECEPTORS 188 2.06e-01 0.053500 5.40e-01
REACTOME FORMATION OF TC NER PRE INCISION COMPLEX 51 2.06e-01 0.102000 5.40e-01
REACTOME L1CAM INTERACTIONS 112 2.06e-01 -0.069200 5.40e-01
REACTOME BASE EXCISION REPAIR 87 2.06e-01 0.078400 5.40e-01
REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING 45 2.06e-01 0.109000 5.40e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12 22 2.08e-01 0.155000 5.40e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES 49 2.08e-01 0.104000 5.40e-01
REACTOME COPI MEDIATED ANTEROGRADE TRANSPORT 101 2.08e-01 0.072500 5.40e-01
REACTOME CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION 11 2.08e-01 -0.219000 5.40e-01
REACTOME ALK MUTANTS BIND TKIS 12 2.08e-01 0.210000 5.40e-01
REACTOME FATTY ACID METABOLISM 170 2.09e-01 -0.055800 5.41e-01
REACTOME CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2 11 2.09e-01 0.219000 5.41e-01
REACTOME BILE ACID AND BILE SALT METABOLISM 45 2.10e-01 -0.108000 5.42e-01
REACTOME PTK6 REGULATES CELL CYCLE 6 2.11e-01 0.295000 5.44e-01
REACTOME GLUCURONIDATION 23 2.11e-01 -0.151000 5.44e-01
REACTOME SHC MEDIATED CASCADE FGFR3 17 2.13e-01 0.175000 5.46e-01
REACTOME SIGNALING BY ACTIVIN 15 2.13e-01 0.186000 5.47e-01
REACTOME CDC42 GTPASE CYCLE 144 2.13e-01 -0.060100 5.47e-01
REACTOME MITOTIC PROPHASE 134 2.14e-01 0.062100 5.48e-01
REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE 17 2.15e-01 0.174000 5.49e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH CDK5 6 2.17e-01 -0.291000 5.52e-01
REACTOME ACETYLCHOLINE REGULATES INSULIN SECRETION 10 2.17e-01 -0.225000 5.52e-01
REACTOME INTRINSIC PATHWAY FOR APOPTOSIS 54 2.17e-01 0.097100 5.52e-01
REACTOME RUNX3 REGULATES WNT SIGNALING 8 2.19e-01 -0.251000 5.55e-01
REACTOME NUCLEAR ENVELOPE BREAKDOWN 52 2.19e-01 0.098500 5.55e-01
REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION 68 2.19e-01 0.086100 5.55e-01
REACTOME TRANSPORT OF ORGANIC ANIONS 10 2.21e-01 -0.224000 5.58e-01
REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS 63 2.21e-01 -0.089100 5.58e-01
REACTOME CHAPERONE MEDIATED AUTOPHAGY 20 2.22e-01 0.158000 5.58e-01
REACTOME DRUG ADME 103 2.22e-01 -0.069600 5.58e-01
REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY 14 2.22e-01 -0.188000 5.58e-01
REACTOME ARACHIDONATE PRODUCTION FROM DAG 5 2.25e-01 -0.314000 5.63e-01
REACTOME TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE 10 2.27e-01 -0.221000 5.67e-01
REACTOME SUMO IS TRANSFERRED FROM E1 TO E2 UBE2I UBC9 7 2.27e-01 0.264000 5.68e-01
REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN 37 2.28e-01 0.114000 5.70e-01
REACTOME SMAC XIAP REGULATED APOPTOTIC RESPONSE 7 2.29e-01 0.263000 5.70e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS 14 2.30e-01 -0.185000 5.72e-01
REACTOME AURKA ACTIVATION BY TPX2 69 2.31e-01 0.083400 5.74e-01
REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI 17 2.31e-01 0.168000 5.74e-01
REACTOME INSULIN RECEPTOR SIGNALLING CASCADE 53 2.33e-01 0.094800 5.75e-01
REACTOME PYROPTOSIS 27 2.33e-01 0.133000 5.75e-01
REACTOME SODIUM COUPLED PHOSPHATE COTRANSPORTERS 5 2.33e-01 0.308000 5.76e-01
REACTOME GASTRULATION 49 2.35e-01 0.098000 5.79e-01
REACTOME ION CHANNEL TRANSPORT 172 2.35e-01 -0.052500 5.79e-01
REACTOME GLUCOSE METABOLISM 90 2.36e-01 0.072200 5.80e-01
REACTOME PRE NOTCH EXPRESSION AND PROCESSING 112 2.37e-01 0.064700 5.80e-01
REACTOME DEFECTS IN VITAMIN AND COFACTOR METABOLISM 21 2.37e-01 -0.149000 5.80e-01
REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING 13 2.38e-01 0.189000 5.81e-01
REACTOME DEFECTIVE LFNG CAUSES SCDO3 5 2.38e-01 -0.305000 5.81e-01
REACTOME FGFR3B LIGAND BINDING AND ACTIVATION 7 2.38e-01 0.257000 5.81e-01
REACTOME VITAMIN B2 RIBOFLAVIN METABOLISM 7 2.39e-01 0.257000 5.82e-01
REACTOME RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES TREGS 9 2.40e-01 0.226000 5.83e-01
REACTOME SUMOYLATION OF TRANSCRIPTION FACTORS 20 2.40e-01 0.152000 5.83e-01
REACTOME DISEASES OF CARBOHYDRATE METABOLISM 31 2.40e-01 0.122000 5.83e-01
REACTOME DOWNSTREAM SIGNAL TRANSDUCTION 29 2.42e-01 0.126000 5.85e-01
REACTOME INLA MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS 9 2.42e-01 0.225000 5.85e-01
REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE 52 2.43e-01 0.093600 5.86e-01
REACTOME VITAMINS 6 2.43e-01 -0.275000 5.86e-01
REACTOME RRNA PROCESSING IN THE MITOCHONDRION 9 2.44e-01 -0.224000 5.86e-01
REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4 33 2.45e-01 -0.117000 5.89e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1 25 2.46e-01 0.134000 5.89e-01
REACTOME SMOOTH MUSCLE CONTRACTION 43 2.46e-01 -0.102000 5.89e-01
REACTOME RECEPTOR MEDIATED MITOPHAGY 10 2.48e-01 -0.211000 5.93e-01
REACTOME SIGNALING BY FGFR 85 2.48e-01 0.072500 5.93e-01
REACTOME CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT 19 2.49e-01 0.153000 5.94e-01
REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT 222 2.52e-01 0.044600 5.99e-01
REACTOME MHC CLASS II ANTIGEN PRESENTATION 121 2.52e-01 0.060300 5.99e-01
REACTOME CYTOPROTECTION BY HMOX1 59 2.54e-01 0.085900 6.02e-01
REACTOME RNA POLYMERASE II PRE TRANSCRIPTION EVENTS 77 2.54e-01 0.075200 6.02e-01
REACTOME SIGNAL AMPLIFICATION 33 2.54e-01 0.115000 6.02e-01
REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION 160 2.55e-01 0.052100 6.03e-01
REACTOME HEME DEGRADATION 15 2.55e-01 -0.170000 6.04e-01
REACTOME CHYLOMICRON REMODELING 10 2.56e-01 -0.207000 6.04e-01
REACTOME SIGNALING BY FGFR IN DISEASE 62 2.56e-01 0.083400 6.04e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE GIP 12 2.57e-01 0.189000 6.04e-01
REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP 41 2.58e-01 -0.102000 6.04e-01
REACTOME NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 11 2.58e-01 -0.197000 6.04e-01
REACTOME ACYL CHAIN REMODELLING OF PS 22 2.58e-01 -0.139000 6.04e-01
REACTOME SIGNALLING TO ERKS 34 2.60e-01 0.112000 6.09e-01
REACTOME INTERLEUKIN 15 SIGNALING 13 2.61e-01 0.180000 6.09e-01
REACTOME SUMO IS PROTEOLYTICALLY PROCESSED 6 2.61e-01 0.265000 6.09e-01
REACTOME SIGNALING BY HEDGEHOG 148 2.61e-01 0.053500 6.09e-01
REACTOME GLYCEROPHOSPHOLIPID CATABOLISM 7 2.62e-01 -0.245000 6.09e-01
REACTOME MATURATION OF PROTEIN 3A 9 2.63e-01 -0.216000 6.10e-01
REACTOME G ALPHA 12 13 SIGNALLING EVENTS 74 2.63e-01 -0.075200 6.10e-01
REACTOME METABOLISM OF FAT SOLUBLE VITAMINS 46 2.64e-01 -0.095200 6.10e-01
REACTOME REGULATION OF INSULIN SECRETION 77 2.64e-01 -0.073600 6.10e-01
REACTOME SHC1 EVENTS IN ERBB4 SIGNALING 14 2.64e-01 0.172000 6.10e-01
REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK 28 2.65e-01 -0.122000 6.10e-01
REACTOME HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE 43 2.66e-01 0.098000 6.12e-01
REACTOME RRNA MODIFICATION IN THE MITOCHONDRION 6 2.66e-01 -0.262000 6.12e-01
REACTOME ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY 5 2.67e-01 0.287000 6.12e-01
REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES 78 2.67e-01 0.072700 6.12e-01
REACTOME ACYL CHAIN REMODELLING OF PG 18 2.69e-01 -0.150000 6.15e-01
REACTOME MASTL FACILITATES MITOTIC PROGRESSION 10 2.69e-01 -0.202000 6.15e-01
REACTOME BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA 17 2.69e-01 0.155000 6.15e-01
REACTOME REDUCTION OF CYTOSOLIC CA LEVELS 11 2.70e-01 -0.192000 6.16e-01
REACTOME SIGNALING BY INSULIN RECEPTOR 80 2.71e-01 0.071100 6.18e-01
REACTOME RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES 16 2.72e-01 -0.159000 6.18e-01
REACTOME SIGNALING BY FGFR1 IN DISEASE 38 2.72e-01 0.103000 6.19e-01
REACTOME METHIONINE SALVAGE PATHWAY 6 2.75e-01 0.257000 6.24e-01
REACTOME TRANSCRIPTION OF THE HIV GENOME 66 2.76e-01 0.077600 6.24e-01
REACTOME VLDL ASSEMBLY 5 2.76e-01 0.281000 6.24e-01
REACTOME SODIUM CALCIUM EXCHANGERS 11 2.77e-01 -0.189000 6.24e-01
REACTOME ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING 9 2.77e-01 -0.209000 6.24e-01
REACTOME HORMONE LIGAND BINDING RECEPTORS 12 2.77e-01 -0.181000 6.24e-01
REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR 19 2.78e-01 0.144000 6.26e-01
REACTOME TNF SIGNALING 54 2.80e-01 0.085100 6.28e-01
REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION 19 2.80e-01 -0.143000 6.29e-01
REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES 91 2.81e-01 0.065400 6.29e-01
REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES 46 2.82e-01 0.091700 6.31e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES 61 2.83e-01 0.079500 6.31e-01
REACTOME INITIATION OF NUCLEAR ENVELOPE NE REFORMATION 18 2.83e-01 0.146000 6.31e-01
REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS 113 2.83e-01 0.058400 6.31e-01
REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION 19 2.84e-01 0.142000 6.31e-01
REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION 59 2.85e-01 0.080500 6.31e-01
REACTOME G2 M DNA REPLICATION CHECKPOINT 5 2.85e-01 0.276000 6.31e-01
REACTOME SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA 52 2.85e-01 0.085700 6.31e-01
REACTOME SIGNALING BY KIT IN DISEASE 20 2.85e-01 0.138000 6.31e-01
REACTOME SPRY REGULATION OF FGF SIGNALING 16 2.86e-01 0.154000 6.32e-01
REACTOME DSCAM INTERACTIONS 11 2.87e-01 -0.185000 6.32e-01
REACTOME REGULATION BY C FLIP 11 2.87e-01 0.185000 6.32e-01
REACTOME INITIAL TRIGGERING OF COMPLEMENT 21 2.88e-01 0.134000 6.32e-01
REACTOME G PROTEIN BETA GAMMA SIGNALLING 30 2.88e-01 0.112000 6.32e-01
REACTOME INACTIVATION OF CDC42 AND RAC1 8 2.88e-01 -0.217000 6.32e-01
REACTOME COMPLEX I BIOGENESIS 49 2.88e-01 0.087700 6.32e-01
REACTOME GDP FUCOSE BIOSYNTHESIS 6 2.89e-01 0.250000 6.32e-01
REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING 32 2.90e-01 0.108000 6.33e-01
REACTOME RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION 22 2.91e-01 0.130000 6.35e-01
REACTOME NEF AND SIGNAL TRANSDUCTION 8 2.92e-01 0.215000 6.36e-01
REACTOME SIGNALING BY MST1 5 2.94e-01 -0.271000 6.40e-01
REACTOME THE ACTIVATION OF ARYLSULFATASES 8 2.95e-01 0.214000 6.40e-01
REACTOME INTERLEUKIN 23 SIGNALING 9 2.95e-01 0.202000 6.40e-01
REACTOME PKMTS METHYLATE HISTONE LYSINES 64 2.95e-01 0.075700 6.40e-01
REACTOME MAPK3 ERK1 ACTIVATION 10 2.96e-01 -0.191000 6.42e-01
REACTOME ATTACHMENT OF GPI ANCHOR TO UPAR 7 2.97e-01 0.228000 6.42e-01
REACTOME DISEASES OF IMMUNE SYSTEM 29 2.97e-01 0.112000 6.42e-01
REACTOME NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 24 2.97e-01 -0.123000 6.42e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3 11 2.99e-01 0.181000 6.44e-01
REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 19 3.00e-01 0.137000 6.44e-01
REACTOME RHOA GTPASE CYCLE 142 3.00e-01 -0.050400 6.44e-01
REACTOME RETINOID CYCLE DISEASE EVENTS 11 3.02e-01 -0.180000 6.49e-01
REACTOME MRNA EDITING C TO U CONVERSION 8 3.03e-01 -0.210000 6.49e-01
REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE 109 3.04e-01 0.057000 6.49e-01
REACTOME PLATELET AGGREGATION PLUG FORMATION 39 3.04e-01 -0.095200 6.49e-01
REACTOME GLYCOGEN STORAGE DISEASES 15 3.04e-01 0.153000 6.49e-01
REACTOME DAG AND IP3 SIGNALING 40 3.05e-01 -0.093700 6.51e-01
REACTOME HYALURONAN UPTAKE AND DEGRADATION 12 3.06e-01 0.171000 6.51e-01
REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY 10 3.07e-01 -0.187000 6.52e-01
REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS 51 3.07e-01 0.082700 6.52e-01
REACTOME CD209 DC SIGN SIGNALING 20 3.08e-01 0.132000 6.52e-01
REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM 20 3.08e-01 0.132000 6.52e-01
REACTOME GRB7 EVENTS IN ERBB2 SIGNALING 5 3.09e-01 0.262000 6.52e-01
REACTOME GOLGI TO ER RETROGRADE TRANSPORT 132 3.10e-01 0.051200 6.52e-01
REACTOME LTC4 CYSLTR MEDIATED IL4 PRODUCTION 6 3.11e-01 -0.239000 6.52e-01
REACTOME SIGNALING BY FGFR1 49 3.11e-01 0.083600 6.52e-01
REACTOME HEDGEHOG OFF STATE 111 3.11e-01 0.055600 6.52e-01
REACTOME PI 3K CASCADE FGFR1 21 3.11e-01 0.128000 6.52e-01
REACTOME RND3 GTPASE CYCLE 41 3.11e-01 -0.091300 6.52e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH PI3K 7 3.11e-01 0.221000 6.52e-01
REACTOME ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT 23 3.12e-01 0.122000 6.52e-01
REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF 53 3.12e-01 -0.080300 6.52e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING 6 3.12e-01 0.238000 6.52e-01
REACTOME HDL ASSEMBLY 8 3.13e-01 -0.206000 6.53e-01
REACTOME METABOLISM OF COFACTORS 19 3.14e-01 0.133000 6.53e-01
REACTOME FRS MEDIATED FGFR1 SIGNALING 23 3.14e-01 0.121000 6.53e-01
REACTOME SELECTIVE AUTOPHAGY 79 3.14e-01 0.065500 6.53e-01
REACTOME FREE FATTY ACIDS REGULATE INSULIN SECRETION 10 3.14e-01 -0.184000 6.53e-01
REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS 118 3.16e-01 -0.053500 6.54e-01
REACTOME ABC TRANSPORTER DISORDERS 76 3.16e-01 0.066500 6.54e-01
REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS 23 3.16e-01 -0.121000 6.54e-01
REACTOME BASIGIN INTERACTIONS 24 3.19e-01 -0.118000 6.57e-01
REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS 91 3.19e-01 0.060500 6.57e-01
REACTOME BIOTIN TRANSPORT AND METABOLISM 10 3.19e-01 -0.182000 6.57e-01
REACTOME HDMS DEMETHYLATE HISTONES 40 3.20e-01 0.090900 6.57e-01
REACTOME KERATAN SULFATE KERATIN METABOLISM 34 3.20e-01 -0.098600 6.57e-01
REACTOME CD28 DEPENDENT PI3K AKT SIGNALING 22 3.21e-01 0.122000 6.59e-01
REACTOME DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX 83 3.23e-01 0.062800 6.60e-01
REACTOME AGGREPHAGY 42 3.23e-01 0.088100 6.60e-01
REACTOME COENZYME A BIOSYNTHESIS 8 3.23e-01 0.202000 6.60e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL 14 3.23e-01 0.152000 6.60e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS 6 3.24e-01 0.233000 6.61e-01
REACTOME TYPE I HEMIDESMOSOME ASSEMBLY 11 3.24e-01 -0.172000 6.61e-01
REACTOME INTERACTION BETWEEN L1 AND ANKYRINS 30 3.25e-01 -0.104000 6.62e-01
REACTOME DEFECTS IN COBALAMIN B12 METABOLISM 13 3.27e-01 -0.157000 6.64e-01
REACTOME ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS 7 3.28e-01 -0.214000 6.64e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR4 14 3.28e-01 0.151000 6.64e-01
REACTOME NOTCH HLH TRANSCRIPTION PATHWAY 24 3.29e-01 -0.115000 6.64e-01
REACTOME CRISTAE FORMATION 27 3.29e-01 0.109000 6.64e-01
REACTOME PEROXISOMAL LIPID METABOLISM 28 3.29e-01 -0.107000 6.64e-01
REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE 277 3.29e-01 0.034100 6.64e-01
REACTOME THE PHOTOTRANSDUCTION CASCADE 32 3.30e-01 -0.099600 6.64e-01
REACTOME SPERM MOTILITY AND TAXES 9 3.30e-01 0.188000 6.64e-01
REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION 26 3.33e-01 -0.110000 6.70e-01
REACTOME NEGATIVE REGULATION OF MET ACTIVITY 20 3.34e-01 0.125000 6.70e-01
REACTOME PEROXISOMAL PROTEIN IMPORT 62 3.34e-01 0.070900 6.70e-01
REACTOME SIGNALLING TO P38 VIA RIT AND RIN 5 3.36e-01 0.249000 6.71e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE 5 3.36e-01 -0.249000 6.71e-01
REACTOME RA BIOSYNTHESIS PATHWAY 22 3.36e-01 0.118000 6.71e-01
REACTOME KSRP KHSRP BINDS AND DESTABILIZES MRNA 17 3.37e-01 0.134000 6.72e-01
REACTOME METABOLISM OF STEROID HORMONES 35 3.38e-01 -0.093600 6.73e-01
REACTOME METABOLISM OF PORPHYRINS 26 3.38e-01 -0.109000 6.73e-01
REACTOME PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS 21 3.39e-01 0.120000 6.74e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION TERMINATION 23 3.41e-01 -0.115000 6.76e-01
REACTOME SYNTHESIS OF DOLICHYL PHOSPHATE 6 3.41e-01 -0.224000 6.77e-01
REACTOME SIGNALING BY MRAS COMPLEX MUTANTS 7 3.42e-01 0.208000 6.77e-01
REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS 32 3.44e-01 0.096600 6.81e-01
REACTOME DNA STRAND ELONGATION 31 3.45e-01 0.097900 6.82e-01
REACTOME FCERI MEDIATED MAPK ACTIVATION 32 3.45e-01 0.096400 6.82e-01
REACTOME PHASE 3 RAPID REPOLARISATION 8 3.47e-01 0.192000 6.83e-01
REACTOME SIGNALING BY ERYTHROPOIETIN 25 3.48e-01 0.108000 6.86e-01
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES 255 3.51e-01 0.033900 6.89e-01
REACTOME PRE NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM 6 3.53e-01 -0.219000 6.92e-01
REACTOME RHO GTPASES ACTIVATE IQGAPS 31 3.53e-01 0.096400 6.92e-01
REACTOME RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION 6 3.54e-01 0.219000 6.92e-01
REACTOME TRANS GOLGI NETWORK VESICLE BUDDING 67 3.54e-01 0.065500 6.92e-01
REACTOME SIGNALING BY ERBB4 57 3.55e-01 0.070800 6.94e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS 7 3.56e-01 0.202000 6.94e-01
REACTOME TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS 82 3.56e-01 -0.059000 6.94e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2 13 3.56e-01 -0.148000 6.94e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL 24 3.57e-01 -0.109000 6.95e-01
REACTOME BICARBONATE TRANSPORTERS 10 3.58e-01 0.168000 6.96e-01
REACTOME ACYL CHAIN REMODELLING OF PC 27 3.58e-01 -0.102000 6.96e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS 11 3.60e-01 0.159000 6.98e-01
REACTOME SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS 12 3.62e-01 0.152000 7.00e-01
REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES 21 3.62e-01 -0.115000 7.00e-01
REACTOME TRANSPORT OF NUCLEOTIDE SUGARS 8 3.63e-01 0.186000 7.01e-01
REACTOME VLDLR INTERNALISATION AND DEGRADATION 16 3.64e-01 0.131000 7.02e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES 10 3.65e-01 0.166000 7.02e-01
REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES 37 3.65e-01 -0.086100 7.02e-01
REACTOME SYNTHESIS OF 12 EICOSATETRAENOIC ACID DERIVATIVES 7 3.65e-01 -0.198000 7.02e-01
REACTOME GLYCOGEN SYNTHESIS 13 3.66e-01 0.145000 7.03e-01
REACTOME PKA ACTIVATION IN GLUCAGON SIGNALLING 17 3.67e-01 -0.126000 7.03e-01
REACTOME DEFECTIVE RIPK1 MEDIATED REGULATED NECROSIS 7 3.67e-01 0.197000 7.03e-01
REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE 20 3.68e-01 0.116000 7.03e-01
REACTOME CHOLESTEROL BIOSYNTHESIS 25 3.69e-01 -0.104000 7.04e-01
REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION 183 3.69e-01 0.038500 7.04e-01
REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE 63 3.70e-01 0.065300 7.04e-01
REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION 8 3.70e-01 -0.183000 7.04e-01
REACTOME MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS 13 3.70e-01 0.144000 7.04e-01
REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE 19 3.71e-01 0.119000 7.04e-01
REACTOME ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA 5 3.72e-01 0.230000 7.06e-01
REACTOME RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION 6 3.74e-01 0.210000 7.08e-01
REACTOME SUMO IS CONJUGATED TO E1 UBA2 SAE1 5 3.74e-01 0.229000 7.08e-01
REACTOME SIGNALING BY RETINOIC ACID 41 3.74e-01 0.080200 7.08e-01
REACTOME NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 11 3.75e-01 0.155000 7.08e-01
REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS 62 3.75e-01 0.065100 7.08e-01
REACTOME TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS 36 3.78e-01 -0.084900 7.13e-01
REACTOME UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN 6 3.80e-01 0.207000 7.15e-01
REACTOME SIGNALING BY FGFR2 IN DISEASE 42 3.81e-01 0.078200 7.16e-01
REACTOME CROSS PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS PHAGOSOMES 6 3.81e-01 -0.206000 7.16e-01
REACTOME WAX AND PLASMALOGEN BIOSYNTHESIS 5 3.81e-01 0.226000 7.16e-01
REACTOME CILIUM ASSEMBLY 190 3.83e-01 0.036700 7.17e-01
REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN 76 3.83e-01 0.057900 7.17e-01
REACTOME TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY 30 3.84e-01 0.091800 7.17e-01
REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS 11 3.84e-01 0.151000 7.17e-01
REACTOME PEXOPHAGY 11 3.85e-01 0.151000 7.17e-01
REACTOME P38MAPK EVENTS 13 3.85e-01 0.139000 7.17e-01
REACTOME DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1 9 3.85e-01 0.167000 7.17e-01
REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS 15 3.87e-01 -0.129000 7.20e-01
REACTOME PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING 5 3.88e-01 0.223000 7.20e-01
REACTOME HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS 7 3.89e-01 0.188000 7.20e-01
REACTOME MYOCLONIC EPILEPSY OF LAFORA 9 3.89e-01 0.166000 7.20e-01
REACTOME REGULATION OF PTEN LOCALIZATION 8 3.89e-01 0.176000 7.20e-01
REACTOME P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1 6 3.90e-01 -0.203000 7.20e-01
REACTOME EPHRIN SIGNALING 17 3.90e-01 0.120000 7.20e-01
REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING 89 3.91e-01 -0.052600 7.20e-01
REACTOME G0 AND EARLY G1 27 3.91e-01 0.095300 7.20e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS 7 3.92e-01 -0.187000 7.20e-01
REACTOME INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL 14 3.92e-01 0.132000 7.20e-01
REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY 23 3.92e-01 0.103000 7.20e-01
REACTOME UNWINDING OF DNA 12 3.93e-01 -0.142000 7.20e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES 15 3.93e-01 0.127000 7.20e-01
REACTOME SULFIDE OXIDATION TO SULFATE 6 3.94e-01 -0.201000 7.20e-01
REACTOME PEPTIDE HORMONE BIOSYNTHESIS 13 3.94e-01 -0.137000 7.20e-01
REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS 12 3.95e-01 0.142000 7.21e-01
REACTOME RAS PROCESSING 22 3.95e-01 0.105000 7.21e-01
REACTOME RIBAVIRIN ADME 11 3.96e-01 0.148000 7.21e-01
REACTOME FGFRL1 MODULATION OF FGFR1 SIGNALING 13 3.98e-01 0.135000 7.22e-01
REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS 101 3.98e-01 -0.048700 7.22e-01
REACTOME NOSTRIN MEDIATED ENOS TRAFFICKING 5 3.98e-01 -0.218000 7.22e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS 9 3.98e-01 -0.163000 7.22e-01
REACTOME CONDENSATION OF PROMETAPHASE CHROMOSOMES 11 3.99e-01 0.147000 7.23e-01
REACTOME CARGO CONCENTRATION IN THE ER 32 3.99e-01 0.086100 7.23e-01
REACTOME SHC MEDIATED CASCADE FGFR1 21 4.00e-01 0.106000 7.24e-01
REACTOME G PROTEIN MEDIATED EVENTS 53 4.02e-01 -0.066600 7.25e-01
REACTOME FATTY ACIDS BOUND TO GPR40 FFAR1 REGULATE INSULIN SECRETION 8 4.03e-01 -0.171000 7.26e-01
REACTOME ACTIVATION OF C3 AND C5 6 4.03e-01 -0.197000 7.26e-01
REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS 29 4.05e-01 0.089400 7.28e-01
REACTOME SIGNALING BY TGFB FAMILY MEMBERS 119 4.05e-01 0.044200 7.29e-01
REACTOME MUSCARINIC ACETYLCHOLINE RECEPTORS 5 4.06e-01 -0.215000 7.29e-01
REACTOME NGF INDEPENDANT TRKA ACTIVATION 5 4.06e-01 -0.215000 7.29e-01
REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE 15 4.07e-01 -0.124000 7.29e-01
REACTOME CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY 12 4.08e-01 0.138000 7.31e-01
REACTOME ATTACHMENT AND ENTRY 16 4.10e-01 -0.119000 7.32e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH RAS 9 4.10e-01 0.159000 7.32e-01
REACTOME LATE SARS COV 2 INFECTION EVENTS 67 4.11e-01 0.058100 7.32e-01
REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION 90 4.11e-01 0.050100 7.32e-01
REACTOME METAL ION SLC TRANSPORTERS 23 4.11e-01 0.099000 7.32e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER 28 4.12e-01 -0.089700 7.32e-01
REACTOME TACHYKININ RECEPTORS BIND TACHYKININS 5 4.12e-01 0.212000 7.32e-01
REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS 299 4.13e-01 0.027500 7.32e-01
REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS 11 4.13e-01 -0.143000 7.32e-01
REACTOME CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY 25 4.13e-01 0.094500 7.32e-01
REACTOME MEIOTIC SYNAPSIS 73 4.17e-01 0.054900 7.37e-01
REACTOME INTERLEUKIN 37 SIGNALING 20 4.17e-01 0.105000 7.37e-01
REACTOME NEUROTOXICITY OF CLOSTRIDIUM TOXINS 10 4.18e-01 0.148000 7.37e-01
REACTOME G1 S SPECIFIC TRANSCRIPTION 28 4.19e-01 0.088300 7.37e-01
REACTOME UBIQUINOL BIOSYNTHESIS 8 4.19e-01 0.165000 7.37e-01
REACTOME ABACAVIR TRANSMEMBRANE TRANSPORT 5 4.19e-01 -0.209000 7.37e-01
REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING 29 4.19e-01 0.086700 7.37e-01
REACTOME STIMULI SENSING CHANNELS 100 4.20e-01 -0.046700 7.37e-01
REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF 17 4.20e-01 0.113000 7.37e-01
REACTOME PCP CE PATHWAY 91 4.22e-01 0.048700 7.40e-01
REACTOME DEFECTIVE B4GALT1 CAUSES B4GALT1 CDG CDG 2D 8 4.25e-01 -0.163000 7.44e-01
REACTOME ION HOMEOSTASIS 52 4.26e-01 -0.063800 7.45e-01
REACTOME IKBA VARIANT LEADS TO EDA ID 6 4.27e-01 0.187000 7.45e-01
REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 44 4.27e-01 0.069100 7.45e-01
REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS 38 4.28e-01 0.074400 7.45e-01
REACTOME COHESIN LOADING ONTO CHROMATIN 8 4.29e-01 0.162000 7.46e-01
REACTOME ATORVASTATIN ADME 9 4.29e-01 -0.152000 7.46e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES 16 4.29e-01 0.114000 7.46e-01
REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL 41 4.31e-01 0.071100 7.48e-01
REACTOME PLATELET CALCIUM HOMEOSTASIS 27 4.31e-01 -0.087500 7.48e-01
REACTOME SIGNALING BY NOTCH1 69 4.34e-01 0.054400 7.52e-01
REACTOME ACTIVATION OF AMPK DOWNSTREAM OF NMDARS 28 4.35e-01 0.085200 7.52e-01
REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION 32 4.36e-01 0.079600 7.52e-01
REACTOME LDL CLEARANCE 19 4.36e-01 -0.103000 7.52e-01
REACTOME INWARDLY RECTIFYING K CHANNELS 35 4.36e-01 -0.076000 7.52e-01
REACTOME DEGRADATION OF CYSTEINE AND HOMOCYSTEINE 15 4.37e-01 -0.116000 7.52e-01
REACTOME ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM 12 4.37e-01 -0.130000 7.52e-01
REACTOME ENDOGENOUS STEROLS 26 4.38e-01 -0.087900 7.52e-01
REACTOME RHOQ GTPASE CYCLE 57 4.39e-01 -0.059300 7.52e-01
REACTOME MET ACTIVATES RAS SIGNALING 11 4.39e-01 0.135000 7.52e-01
REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC 198 4.39e-01 0.031900 7.52e-01
REACTOME INFECTION WITH MYCOBACTERIUM TUBERCULOSIS 25 4.39e-01 0.089400 7.52e-01
REACTOME INTERLEUKIN 9 SIGNALING 7 4.40e-01 0.168000 7.53e-01
REACTOME ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN 13 4.42e-01 0.123000 7.55e-01
REACTOME TRP CHANNELS 27 4.45e-01 -0.084900 7.60e-01
REACTOME EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION 27 4.46e-01 -0.084700 7.60e-01
REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX 57 4.47e-01 0.058200 7.60e-01
REACTOME CD22 MEDIATED BCR REGULATION 5 4.47e-01 0.196000 7.60e-01
REACTOME BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS 10 4.47e-01 -0.139000 7.60e-01
REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING 33 4.49e-01 0.076100 7.63e-01
REACTOME SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS 16 4.50e-01 0.109000 7.64e-01
REACTOME SARS COV 2 TARGETS PDZ PROTEINS IN CELL CELL JUNCTION 5 4.51e-01 -0.194000 7.65e-01
REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS 30 4.52e-01 0.079400 7.65e-01
REACTOME DISORDERS OF TRANSMEMBRANE TRANSPORTERS 170 4.53e-01 0.033400 7.65e-01
REACTOME NR1H2 AND NR1H3 MEDIATED SIGNALING 46 4.53e-01 -0.063900 7.65e-01
REACTOME HEMOSTASIS 591 4.54e-01 0.018000 7.65e-01
REACTOME BH3 ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI APOPTOTIC BCL 2 MEMBERS 9 4.54e-01 0.144000 7.65e-01
REACTOME RAC3 GTPASE CYCLE 85 4.55e-01 0.046900 7.65e-01
REACTOME PIWI INTERACTING RNA PIRNA BIOGENESIS 29 4.55e-01 0.080100 7.65e-01
REACTOME FGFR2 ALTERNATIVE SPLICING 27 4.55e-01 0.083000 7.65e-01
REACTOME INTERLEUKIN 6 FAMILY SIGNALING 24 4.56e-01 0.087900 7.65e-01
REACTOME RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS 5 4.56e-01 0.192000 7.65e-01
REACTOME HDL REMODELING 10 4.59e-01 -0.135000 7.68e-01
REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE 71 4.60e-01 0.050800 7.69e-01
REACTOME GPCR LIGAND BINDING 444 4.60e-01 0.020400 7.70e-01
REACTOME NETRIN MEDIATED REPULSION SIGNALS 8 4.61e-01 -0.150000 7.70e-01
REACTOME ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS 5 4.62e-01 -0.190000 7.71e-01
REACTOME PI5P REGULATES TP53 ACETYLATION 9 4.62e-01 0.142000 7.71e-01
REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE 37 4.65e-01 -0.069400 7.73e-01
REACTOME RESPONSE OF MTB TO PHAGOCYTOSIS 22 4.66e-01 0.089800 7.73e-01
REACTOME RECYCLING PATHWAY OF L1 43 4.66e-01 0.064300 7.73e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION 41 4.66e-01 -0.065800 7.73e-01
REACTOME ESTROGEN DEPENDENT GENE EXPRESSION 140 4.66e-01 0.035700 7.73e-01
REACTOME RECYCLING OF EIF2 GDP 7 4.68e-01 0.158000 7.75e-01
REACTOME RIP MEDIATED NFKB ACTIVATION VIA ZBP1 16 4.69e-01 0.105000 7.75e-01
REACTOME CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND 9 4.69e-01 -0.139000 7.75e-01
REACTOME SUPPRESSION OF APOPTOSIS 7 4.69e-01 -0.158000 7.75e-01
REACTOME MRNA EDITING 10 4.70e-01 -0.132000 7.75e-01
REACTOME TELOMERE C STRAND SYNTHESIS INITIATION 12 4.71e-01 0.120000 7.75e-01
REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION 23 4.71e-01 0.086900 7.75e-01
REACTOME CA2 PATHWAY 62 4.72e-01 -0.052800 7.76e-01
REACTOME EARLY PHASE OF HIV LIFE CYCLE 14 4.73e-01 0.111000 7.76e-01
REACTOME ERKS ARE INACTIVATED 13 4.73e-01 -0.115000 7.76e-01
REACTOME CONJUGATION OF BENZOATE WITH GLYCINE 6 4.73e-01 0.169000 7.76e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR2 29 4.74e-01 0.076900 7.76e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN 13 4.74e-01 -0.115000 7.76e-01
REACTOME NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 22 4.76e-01 0.087900 7.78e-01
REACTOME INTERLEUKIN 27 SIGNALING 11 4.78e-01 0.124000 7.80e-01
REACTOME XENOBIOTICS 22 4.78e-01 0.087300 7.81e-01
REACTOME ARMS MEDIATED ACTIVATION 7 4.79e-01 0.154000 7.81e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES 12 4.80e-01 0.118000 7.81e-01
REACTOME REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION 9 4.80e-01 0.136000 7.82e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1 31 4.81e-01 0.073100 7.82e-01
REACTOME DEFECTIVE F9 ACTIVATION 5 4.82e-01 0.182000 7.82e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS 15 4.83e-01 0.105000 7.83e-01
REACTOME SIGNALING BY GPCR 673 4.83e-01 -0.015900 7.83e-01
REACTOME SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER 15 4.84e-01 0.104000 7.83e-01
REACTOME SIGNALING BY NODAL 20 4.84e-01 0.090300 7.83e-01
REACTOME TRIGLYCERIDE CATABOLISM 23 4.85e-01 -0.084100 7.83e-01
REACTOME RUNX3 REGULATES CDKN1A TRANSCRIPTION 7 4.85e-01 -0.152000 7.83e-01
REACTOME PI3K EVENTS IN ERBB2 SIGNALING 16 4.85e-01 0.101000 7.83e-01
REACTOME RHOG GTPASE CYCLE 71 4.86e-01 -0.047800 7.83e-01
REACTOME NFE2L2 REGULATING ANTI OXIDANT DETOXIFICATION ENZYMES 17 4.87e-01 0.097300 7.83e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1 16 4.87e-01 0.100000 7.83e-01
REACTOME FGFR3 LIGAND BINDING AND ACTIVATION 12 4.88e-01 0.116000 7.83e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES 11 4.89e-01 0.121000 7.83e-01
REACTOME DEADENYLATION DEPENDENT MRNA DECAY 56 4.89e-01 0.053500 7.83e-01
REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS 16 4.90e-01 -0.099700 7.83e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS 34 4.91e-01 -0.068300 7.83e-01
REACTOME SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS 43 4.91e-01 -0.060700 7.83e-01
REACTOME ZINC TRANSPORTERS 15 4.92e-01 0.103000 7.83e-01
REACTOME RAC2 GTPASE CYCLE 81 4.92e-01 0.044200 7.83e-01
REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT 99 4.93e-01 0.039900 7.83e-01
REACTOME ACTIVATION OF NIMA KINASES NEK9 NEK6 NEK7 7 4.94e-01 0.149000 7.83e-01
REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE 69 4.94e-01 -0.047600 7.83e-01
REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS 5 4.94e-01 -0.177000 7.83e-01
REACTOME TRAIL SIGNALING 8 4.94e-01 0.140000 7.83e-01
REACTOME WNT MEDIATED ACTIVATION OF DVL 8 4.94e-01 -0.140000 7.83e-01
REACTOME NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 25 4.94e-01 0.079000 7.83e-01
REACTOME FORMATION OF APOPTOSOME 10 4.95e-01 0.125000 7.83e-01
REACTOME SIGNALING BY FGFR2 IIIA TM 19 4.95e-01 0.090300 7.84e-01
REACTOME HEME BIOSYNTHESIS 13 4.96e-01 -0.109000 7.84e-01
REACTOME POTENTIAL THERAPEUTICS FOR SARS 92 4.98e-01 -0.040900 7.85e-01
REACTOME REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM 11 4.99e-01 -0.118000 7.85e-01
REACTOME CREATINE METABOLISM 9 4.99e-01 0.130000 7.85e-01
REACTOME MISCELLANEOUS TRANSPORT AND BINDING EVENTS 24 4.99e-01 -0.079700 7.85e-01
REACTOME VITAMIN B1 THIAMIN METABOLISM 5 5.00e-01 0.174000 7.87e-01
REACTOME METABOLISM OF CARBOHYDRATES 279 5.02e-01 -0.023400 7.88e-01
REACTOME N GLYCAN TRIMMING AND ELONGATION IN THE CIS GOLGI 5 5.02e-01 0.173000 7.88e-01
REACTOME DEFECTS IN BIOTIN BTN METABOLISM 8 5.04e-01 -0.136000 7.88e-01
REACTOME REGULATION OF NF KAPPA B SIGNALING 17 5.05e-01 0.093500 7.88e-01
REACTOME RELAXIN RECEPTORS 8 5.05e-01 0.136000 7.88e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST 18 5.06e-01 0.090600 7.88e-01
REACTOME SIGNALING BY NTRKS 132 5.07e-01 0.033400 7.88e-01
REACTOME ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS 41 5.08e-01 0.059800 7.88e-01
REACTOME PRE NOTCH PROCESSING IN GOLGI 18 5.08e-01 -0.090200 7.88e-01
REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION 16 5.08e-01 0.095600 7.88e-01
REACTOME METABOLISM OF NUCLEOTIDES 94 5.08e-01 0.039500 7.88e-01
REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS 11 5.08e-01 0.115000 7.88e-01
REACTOME NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 19 5.09e-01 -0.087500 7.88e-01
REACTOME GLUCONEOGENESIS 33 5.10e-01 0.066300 7.88e-01
REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS 83 5.10e-01 0.041800 7.88e-01
REACTOME CREATION OF C4 AND C2 ACTIVATORS 14 5.11e-01 0.102000 7.88e-01
REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING 6 5.11e-01 -0.155000 7.88e-01
REACTOME GLUTATHIONE CONJUGATION 33 5.11e-01 0.066100 7.88e-01
REACTOME TRANSCRIPTIONAL REGULATION BY MECP2 60 5.11e-01 0.049000 7.88e-01
REACTOME CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE 49 5.11e-01 -0.054200 7.88e-01
REACTOME SIGNAL ATTENUATION 10 5.11e-01 -0.120000 7.88e-01
REACTOME COPII MEDIATED VESICLE TRANSPORT 66 5.13e-01 0.046600 7.88e-01
REACTOME MET ACTIVATES PI3K AKT SIGNALING 6 5.13e-01 0.154000 7.88e-01
REACTOME RHOU GTPASE CYCLE 37 5.13e-01 0.062100 7.88e-01
REACTOME GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION 34 5.14e-01 0.064700 7.88e-01
REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE 22 5.15e-01 -0.080200 7.88e-01
REACTOME NEUROTRANSMITTER CLEARANCE 9 5.15e-01 0.125000 7.88e-01
REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA 11 5.15e-01 -0.113000 7.88e-01
REACTOME RAC1 GTPASE CYCLE 172 5.16e-01 -0.028700 7.88e-01
REACTOME SYNTHESIS OF 5 EICOSATETRAENOIC ACIDS 9 5.16e-01 -0.125000 7.88e-01
REACTOME FRS MEDIATED FGFR2 SIGNALING 24 5.16e-01 0.076600 7.88e-01
REACTOME INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES 28 5.17e-01 0.070800 7.88e-01
REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE 17 5.17e-01 0.090700 7.88e-01
REACTOME NEF MEDIATED CD8 DOWN REGULATION 7 5.18e-01 -0.141000 7.88e-01
REACTOME GP1B IX V ACTIVATION SIGNALLING 11 5.18e-01 0.112000 7.88e-01
REACTOME AMINO ACIDS REGULATE MTORC1 53 5.19e-01 -0.051200 7.88e-01
REACTOME DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS 19 5.19e-01 0.085500 7.88e-01
REACTOME ERBB2 ACTIVATES PTK6 SIGNALING 13 5.20e-01 0.103000 7.88e-01
REACTOME ACTIVATION OF BH3 ONLY PROTEINS 30 5.20e-01 0.067800 7.88e-01
REACTOME DISEASES OF BASE EXCISION REPAIR 5 5.20e-01 -0.166000 7.88e-01
REACTOME SENSING OF DNA DOUBLE STRAND BREAKS 6 5.22e-01 0.151000 7.90e-01
REACTOME FGFR1B LIGAND BINDING AND ACTIVATION 6 5.23e-01 -0.151000 7.90e-01
REACTOME PI 3K CASCADE FGFR2 22 5.23e-01 0.078600 7.90e-01
REACTOME LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX 5 5.23e-01 0.165000 7.90e-01
REACTOME CAMK IV MEDIATED PHOSPHORYLATION OF CREB 10 5.25e-01 -0.116000 7.91e-01
REACTOME IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN 5 5.25e-01 -0.164000 7.91e-01
REACTOME REGULATION OF TP53 EXPRESSION AND DEGRADATION 37 5.25e-01 0.060400 7.91e-01
REACTOME TRNA MODIFICATION IN THE MITOCHONDRION 8 5.27e-01 0.129000 7.91e-01
REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY 29 5.27e-01 0.067900 7.91e-01
REACTOME GABA B RECEPTOR ACTIVATION 43 5.28e-01 -0.055700 7.91e-01
REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS 19 5.28e-01 -0.083700 7.91e-01
REACTOME SYNTHESIS OF PC 27 5.29e-01 0.070000 7.92e-01
REACTOME RAB REGULATION OF TRAFFICKING 110 5.30e-01 0.034700 7.92e-01
REACTOME BIOLOGICAL OXIDATIONS 210 5.30e-01 -0.025100 7.92e-01
REACTOME DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE 30 5.31e-01 0.066100 7.92e-01
REACTOME BETA DEFENSINS 27 5.31e-01 0.069600 7.92e-01
REACTOME DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A 5 5.32e-01 -0.162000 7.92e-01
REACTOME RUNX2 REGULATES BONE DEVELOPMENT 29 5.32e-01 0.067000 7.92e-01
REACTOME EPITHELIAL MESENCHYMAL TRANSITION EMT DURING GASTRULATION 7 5.32e-01 -0.136000 7.92e-01
REACTOME APOPTOTIC EXECUTION PHASE 49 5.36e-01 0.051100 7.96e-01
REACTOME MITOPHAGY 28 5.38e-01 0.067300 7.96e-01
REACTOME SARS COV 1 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS 16 5.38e-01 0.089000 7.96e-01
REACTOME NUCLEOTIDE BIOSYNTHESIS 14 5.38e-01 -0.095000 7.96e-01
REACTOME IRE1ALPHA ACTIVATES CHAPERONES 48 5.38e-01 0.051300 7.96e-01
REACTOME OAS ANTIVIRAL RESPONSE 8 5.39e-01 -0.126000 7.96e-01
REACTOME PROTEIN REPAIR 6 5.39e-01 0.145000 7.96e-01
REACTOME MUCOPOLYSACCHARIDOSES 10 5.39e-01 0.112000 7.96e-01
REACTOME NEGATIVE REGULATION OF ACTIVITY OF TFAP2 AP 2 FAMILY TRANSCRIPTION FACTORS 10 5.39e-01 -0.112000 7.96e-01
REACTOME LINOLEIC ACID LA METABOLISM 7 5.42e-01 -0.133000 7.98e-01
REACTOME ORGANIC CATION TRANSPORT 10 5.42e-01 -0.111000 7.98e-01
REACTOME REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR 11 5.42e-01 0.106000 7.98e-01
REACTOME CREB PHOSPHORYLATION 6 5.42e-01 0.144000 7.98e-01
REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE 5 5.45e-01 -0.156000 8.00e-01
REACTOME ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS 20 5.46e-01 0.078000 8.00e-01
REACTOME ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS 20 5.46e-01 0.077900 8.00e-01
REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS 11 5.46e-01 -0.105000 8.00e-01
REACTOME NEUROFASCIN INTERACTIONS 6 5.46e-01 -0.142000 8.00e-01
REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE 63 5.47e-01 -0.043800 8.01e-01
REACTOME FREE FATTY ACID RECEPTORS 5 5.48e-01 -0.155000 8.01e-01
REACTOME SEMA3A PAK DEPENDENT AXON REPULSION 14 5.48e-01 0.092700 8.01e-01
REACTOME SIGNALING BY LRP5 MUTANTS 6 5.50e-01 0.141000 8.03e-01
REACTOME PHOSPHORYLATION OF EMI1 6 5.53e-01 0.140000 8.05e-01
REACTOME RHO GTPASES ACTIVATE ROCKS 19 5.53e-01 0.078600 8.05e-01
REACTOME ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA 15 5.54e-01 0.088300 8.05e-01
REACTOME LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS 19 5.54e-01 0.078500 8.05e-01
REACTOME SURFACTANT METABOLISM 28 5.54e-01 -0.064600 8.05e-01
REACTOME LYSOSPHINGOLIPID AND LPA RECEPTORS 14 5.55e-01 0.091200 8.05e-01
REACTOME FATTY ACIDS 15 5.56e-01 0.087700 8.05e-01
REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE 10 5.57e-01 -0.107000 8.05e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING 5 5.57e-01 0.152000 8.05e-01
REACTOME GROWTH HORMONE RECEPTOR SIGNALING 24 5.57e-01 -0.069200 8.05e-01
REACTOME SIGNALING BY VEGF 102 5.57e-01 -0.033600 8.05e-01
REACTOME JOSEPHIN DOMAIN DUBS 11 5.58e-01 0.102000 8.05e-01
REACTOME REGULATION OF NPAS4 GENE EXPRESSION 13 5.58e-01 -0.093700 8.05e-01
REACTOME OTHER INTERLEUKIN SIGNALING 24 5.59e-01 -0.068900 8.05e-01
REACTOME CONSTITUTIVE SIGNALING BY EGFRVIII 15 5.59e-01 0.087100 8.05e-01
REACTOME ARYL HYDROCARBON RECEPTOR SIGNALLING 6 5.60e-01 0.137000 8.06e-01
REACTOME PROLONGED ERK ACTIVATION EVENTS 14 5.61e-01 0.089800 8.06e-01
REACTOME SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION 8 5.64e-01 -0.118000 8.10e-01
REACTOME VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS 42 5.65e-01 0.051300 8.10e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS 12 5.66e-01 -0.095700 8.10e-01
REACTOME KERATAN SULFATE DEGRADATION 13 5.66e-01 -0.092000 8.10e-01
REACTOME FIBRONECTIN MATRIX FORMATION 6 5.66e-01 0.135000 8.10e-01
REACTOME LEISHMANIA INFECTION 156 5.66e-01 0.026600 8.10e-01
REACTOME NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION 20 5.67e-01 -0.073900 8.11e-01
REACTOME ORGANIC ANION TRANSPORTERS 10 5.69e-01 -0.104000 8.12e-01
REACTOME TAK1 DEPENDENT IKK AND NF KAPPA B ACTIVATION 41 5.69e-01 0.051400 8.12e-01
REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT 15 5.70e-01 -0.084700 8.12e-01
REACTOME PROTEIN METHYLATION 17 5.71e-01 0.079300 8.13e-01
REACTOME ADRENOCEPTORS 9 5.72e-01 0.109000 8.13e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE 8 5.72e-01 -0.115000 8.13e-01
REACTOME CREB3 FACTORS ACTIVATE GENES 8 5.72e-01 0.115000 8.13e-01
REACTOME DEFECTIVE EXT2 CAUSES EXOSTOSES 2 12 5.74e-01 -0.093800 8.13e-01
REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM 45 5.74e-01 -0.048500 8.13e-01
REACTOME LYSINE CATABOLISM 12 5.74e-01 0.093700 8.13e-01
REACTOME PREDNISONE ADME 10 5.74e-01 0.103000 8.13e-01
REACTOME METABOLISM OF FOLATE AND PTERINES 17 5.75e-01 0.078700 8.13e-01
REACTOME ACTIVATION OF SMO 18 5.76e-01 0.076100 8.14e-01
REACTOME SIGNALING BY FGFR4 IN DISEASE 11 5.77e-01 0.097200 8.14e-01
REACTOME LRR FLII INTERACTING PROTEIN 1 LRRFIP1 ACTIVATES TYPE I IFN PRODUCTION 5 5.79e-01 -0.143000 8.17e-01
REACTOME FRUCTOSE CATABOLISM 5 5.80e-01 -0.143000 8.17e-01
REACTOME CA2 ACTIVATED K CHANNELS 9 5.83e-01 0.106000 8.20e-01
REACTOME CYP2E1 REACTIONS 10 5.83e-01 0.100000 8.20e-01
REACTOME FGFR1 LIGAND BINDING AND ACTIVATION 15 5.84e-01 0.081700 8.20e-01
REACTOME DEFENSINS 33 5.85e-01 0.055000 8.20e-01
REACTOME SYNTHESIS OF UDP N ACETYL GLUCOSAMINE 7 5.85e-01 0.119000 8.20e-01
REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS 81 5.85e-01 0.035100 8.20e-01
REACTOME ACYL CHAIN REMODELLING OF PE 29 5.85e-01 -0.058500 8.20e-01
REACTOME DEADENYLATION OF MRNA 25 5.86e-01 -0.063000 8.20e-01
REACTOME DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS 14 5.89e-01 -0.083400 8.24e-01
REACTOME MET RECEPTOR RECYCLING 10 5.92e-01 0.097900 8.25e-01
REACTOME SIGNALING BY WNT 318 5.93e-01 0.017400 8.25e-01
REACTOME SYNTHESIS OF PA 38 5.93e-01 -0.050100 8.25e-01
REACTOME REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS 11 5.93e-01 -0.093100 8.25e-01
REACTOME ACTIVATION OF RAS IN B CELLS 5 5.94e-01 0.138000 8.25e-01
REACTOME AUTOPHAGY 144 5.94e-01 0.025800 8.25e-01
REACTOME MITOCHONDRIAL CALCIUM ION TRANSPORT 23 5.94e-01 -0.064200 8.25e-01
REACTOME NICOTINAMIDE SALVAGING 19 5.94e-01 0.070600 8.25e-01
REACTOME CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA 63 5.94e-01 0.038800 8.25e-01
REACTOME INTEGRATION OF PROVIRUS 9 5.95e-01 0.102000 8.25e-01
REACTOME RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK 47 5.96e-01 0.044700 8.26e-01
REACTOME REGULATION OF PTEN STABILITY AND ACTIVITY 67 5.96e-01 0.037400 8.26e-01
REACTOME FATTY ACYL COA BIOSYNTHESIS 36 5.97e-01 -0.050900 8.26e-01
REACTOME SIGNALLING TO RAS 20 5.99e-01 0.067900 8.28e-01
REACTOME HYDROLYSIS OF LPC 9 6.01e-01 -0.101000 8.30e-01
REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS 46 6.03e-01 0.044300 8.31e-01
REACTOME ERYTHROPOIETIN ACTIVATES RAS 14 6.03e-01 0.080300 8.31e-01
REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES 34 6.04e-01 0.051400 8.32e-01
REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET 8 6.05e-01 -0.106000 8.33e-01
REACTOME DEX H BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION 7 6.10e-01 0.111000 8.38e-01
REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ 6 6.10e-01 0.120000 8.38e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG 7 6.10e-01 -0.111000 8.38e-01
REACTOME SEROTONIN NEUROTRANSMITTER RELEASE CYCLE 17 6.11e-01 0.071300 8.38e-01
REACTOME SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA PHE 6 6.11e-01 0.120000 8.38e-01
REACTOME TELOMERE EXTENSION BY TELOMERASE 22 6.12e-01 0.062500 8.38e-01
REACTOME EPH EPHRIN MEDIATED REPULSION OF CELLS 50 6.13e-01 -0.041400 8.38e-01
REACTOME HISTIDINE CATABOLISM 8 6.13e-01 -0.103000 8.39e-01
REACTOME RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION 8 6.14e-01 -0.103000 8.39e-01
REACTOME G ALPHA I SIGNALLING EVENTS 304 6.15e-01 0.016800 8.40e-01
REACTOME LIPID PARTICLE ORGANIZATION 6 6.16e-01 -0.118000 8.41e-01
REACTOME PURINE CATABOLISM 17 6.18e-01 -0.069900 8.41e-01
REACTOME PHOSPHOLIPID METABOLISM 201 6.18e-01 -0.020400 8.41e-01
REACTOME AQUAPORIN MEDIATED TRANSPORT 51 6.19e-01 0.040300 8.42e-01
REACTOME VITAMIN D CALCIFEROL METABOLISM 12 6.21e-01 -0.082500 8.42e-01
REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS 11 6.21e-01 -0.086000 8.42e-01
REACTOME DIGESTION OF DIETARY LIPID 7 6.22e-01 -0.108000 8.42e-01
REACTOME GAB1 SIGNALOSOME 17 6.23e-01 0.069000 8.42e-01
REACTOME TOXICITY OF BOTULINUM TOXIN TYPE D BOTD 5 6.23e-01 0.127000 8.42e-01
REACTOME CALCITONIN LIKE LIGAND RECEPTORS 10 6.23e-01 0.089700 8.42e-01
REACTOME METABOLISM OF VITAMINS AND COFACTORS 185 6.24e-01 -0.020900 8.42e-01
REACTOME INOSITOL PHOSPHATE METABOLISM 45 6.24e-01 -0.042200 8.42e-01
REACTOME VITAMIN B5 PANTOTHENATE METABOLISM 16 6.24e-01 0.070700 8.42e-01
REACTOME IRS ACTIVATION 5 6.25e-01 -0.126000 8.42e-01
REACTOME CHONDROITIN SULFATE BIOSYNTHESIS 18 6.25e-01 0.066500 8.42e-01
REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX 21 6.25e-01 -0.061500 8.42e-01
REACTOME PHASE 1 INACTIVATION OF FAST NA CHANNELS 6 6.26e-01 0.115000 8.42e-01
REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING 16 6.28e-01 0.069900 8.45e-01
REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION 32 6.29e-01 0.049300 8.46e-01
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION 81 6.30e-01 0.030900 8.46e-01
REACTOME GLUCOCORTICOID BIOSYNTHESIS 10 6.31e-01 0.087800 8.46e-01
REACTOME SIGNALING BY LEPTIN 11 6.34e-01 -0.082900 8.49e-01
REACTOME UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION 19 6.35e-01 -0.062900 8.49e-01
REACTOME NEURONAL SYSTEM 388 6.36e-01 -0.014000 8.49e-01
REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE 17 6.36e-01 -0.066300 8.49e-01
REACTOME GABA RECEPTOR ACTIVATION 57 6.37e-01 -0.036200 8.49e-01
REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS 23 6.37e-01 -0.056900 8.49e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY DVL INTERACTING PROTEINS 5 6.37e-01 -0.122000 8.49e-01
REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN 19 6.39e-01 0.062300 8.49e-01
REACTOME REGULATION OF RUNX1 EXPRESSION AND ACTIVITY 17 6.39e-01 0.065800 8.49e-01
REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS 123 6.39e-01 -0.024500 8.49e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION 29 6.39e-01 0.050400 8.49e-01
REACTOME BASE EXCISION REPAIR AP SITE FORMATION 59 6.39e-01 0.035300 8.49e-01
REACTOME HS GAG DEGRADATION 19 6.40e-01 0.062000 8.49e-01
REACTOME DEFECTIVE CHST14 CAUSES EDS MUSCULOCONTRACTURAL TYPE 7 6.40e-01 0.102000 8.49e-01
REACTOME FCERI MEDIATED CA 2 MOBILIZATION 30 6.41e-01 0.049200 8.49e-01
REACTOME ACTIVATION OF RAC1 12 6.42e-01 0.077500 8.49e-01
REACTOME HUR ELAVL1 BINDS AND STABILIZES MRNA 8 6.42e-01 -0.094900 8.49e-01
REACTOME PURINE SALVAGE 12 6.42e-01 0.077400 8.49e-01
REACTOME SIGNALING BY MAPK MUTANTS 6 6.45e-01 0.108000 8.53e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE 5 6.46e-01 -0.118000 8.53e-01
REACTOME METHYLATION 14 6.48e-01 0.070500 8.53e-01
REACTOME ENOS ACTIVATION 11 6.48e-01 0.079600 8.53e-01
REACTOME RHO GTPASES ACTIVATE NADPH OXIDASES 21 6.48e-01 -0.057600 8.53e-01
REACTOME SHC1 EVENTS IN ERBB2 SIGNALING 22 6.48e-01 0.056200 8.53e-01
REACTOME INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION 21 6.49e-01 -0.057400 8.53e-01
REACTOME GERM LAYER FORMATION AT GASTRULATION 17 6.50e-01 0.063600 8.53e-01
REACTOME SIGNALING BY NOTCH1 T 7 9 NOTCH1 M1580 K2555 TRANSLOCATION MUTANT 7 6.53e-01 -0.098200 8.57e-01
REACTOME HIV TRANSCRIPTION ELONGATION 42 6.53e-01 0.040000 8.57e-01
REACTOME RHO GTPASE CYCLE 423 6.55e-01 0.012700 8.57e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD4 15 6.55e-01 0.066600 8.57e-01
REACTOME MITOCHONDRIAL BIOGENESIS 87 6.55e-01 0.027700 8.57e-01
REACTOME FGFR2C LIGAND BINDING AND ACTIVATION 12 6.56e-01 0.074200 8.57e-01
REACTOME 2 LTR CIRCLE FORMATION 7 6.56e-01 0.097100 8.57e-01
REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS 12 6.57e-01 -0.073900 8.58e-01
REACTOME RND2 GTPASE CYCLE 42 6.60e-01 -0.039200 8.61e-01
REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS 42 6.60e-01 0.039200 8.61e-01
REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX 36 6.63e-01 -0.042000 8.62e-01
REACTOME SIGNALING BY ERBB2 ECD MUTANTS 16 6.64e-01 0.062700 8.62e-01
REACTOME ROLE OF ABL IN ROBO SLIT SIGNALING 8 6.64e-01 0.088700 8.62e-01
REACTOME INTERLEUKIN 6 SIGNALING 11 6.64e-01 -0.075600 8.62e-01
REACTOME REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA 15 6.65e-01 0.064600 8.62e-01
REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS 21 6.65e-01 0.054600 8.62e-01
REACTOME GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION 14 6.65e-01 0.066800 8.62e-01
REACTOME TRANSCRIPTIONAL REGULATION BY VENTX 41 6.66e-01 0.039000 8.62e-01
REACTOME GLYCOGEN METABOLISM 22 6.67e-01 0.053000 8.62e-01
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION 250 6.67e-01 -0.015800 8.62e-01
REACTOME SARS COV 2 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS 12 6.70e-01 0.071100 8.65e-01
REACTOME CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN 45 6.70e-01 -0.036700 8.65e-01
REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS 6 6.73e-01 0.099400 8.68e-01
REACTOME METABOLISM OF INGESTED SEMET SEC MESEC INTO H2SE 7 6.75e-01 -0.091500 8.70e-01
REACTOME TBC RABGAPS 40 6.76e-01 0.038200 8.70e-01
REACTOME GLUTAMATE AND GLUTAMINE METABOLISM 13 6.77e-01 0.066700 8.71e-01
REACTOME RHOT1 GTPASE CYCLE 5 6.78e-01 0.107000 8.72e-01
REACTOME RUNX2 REGULATES CHONDROCYTE MATURATION 5 6.78e-01 -0.107000 8.72e-01
REACTOME DISSOLUTION OF FIBRIN CLOT 13 6.79e-01 -0.066200 8.72e-01
REACTOME REGULATION OF PTEN MRNA TRANSLATION 9 6.80e-01 -0.079500 8.72e-01
REACTOME MET ACTIVATES PTPN11 5 6.83e-01 0.105000 8.75e-01
REACTOME PHASE 2 PLATEAU PHASE 14 6.83e-01 0.063000 8.75e-01
REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE 21 6.85e-01 0.051200 8.76e-01
REACTOME SUMOYLATION OF IMMUNE RESPONSE PROTEINS 10 6.85e-01 -0.074100 8.76e-01
REACTOME TRAF6 MEDIATED NF KB ACTIVATION 24 6.87e-01 -0.047500 8.78e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS 5 6.87e-01 0.104000 8.78e-01
REACTOME PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING 11 6.88e-01 -0.069900 8.78e-01
REACTOME CS DS DEGRADATION 12 6.89e-01 0.066600 8.78e-01
REACTOME MTORC1 MEDIATED SIGNALLING 23 6.90e-01 0.048100 8.78e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE 20 6.90e-01 0.051500 8.78e-01
REACTOME FORMATION OF AXIAL MESODERM 14 6.90e-01 0.061500 8.78e-01
REACTOME ONCOGENIC MAPK SIGNALING 79 6.91e-01 -0.025800 8.78e-01
REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB 19 6.92e-01 -0.052500 8.79e-01
REACTOME SYNTHESIS OF DIPHTHAMIDE EEF2 8 6.93e-01 0.080700 8.79e-01
REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER 49 6.93e-01 0.032600 8.79e-01
REACTOME NRCAM INTERACTIONS 6 6.94e-01 -0.092700 8.79e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY 19 6.95e-01 -0.052000 8.79e-01
REACTOME CA DEPENDENT EVENTS 36 6.97e-01 -0.037600 8.81e-01
REACTOME SEMA4D IN SEMAPHORIN SIGNALING 24 6.97e-01 -0.045900 8.81e-01
REACTOME ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA 9 6.98e-01 0.074800 8.81e-01
REACTOME MIRO GTPASE CYCLE 8 6.98e-01 0.079200 8.81e-01
REACTOME SHC RELATED EVENTS TRIGGERED BY IGF1R 9 6.99e-01 0.074400 8.82e-01
REACTOME GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION 7 7.00e-01 -0.084100 8.82e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH PI3K 6 7.01e-01 -0.090500 8.82e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL 15 7.02e-01 -0.057100 8.82e-01
REACTOME REGULATION OF BETA CELL DEVELOPMENT 41 7.02e-01 0.034600 8.82e-01
REACTOME RAF ACTIVATION 33 7.03e-01 0.038300 8.83e-01
REACTOME RNA POLYMERASE III CHAIN ELONGATION 18 7.05e-01 -0.051600 8.85e-01
REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS 27 7.06e-01 0.041900 8.86e-01
REACTOME BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA 5 7.07e-01 -0.097200 8.86e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX IN CANCER 8 7.08e-01 0.076400 8.87e-01
REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE 9 7.09e-01 -0.071800 8.87e-01
REACTOME FGFR2B LIGAND BINDING AND ACTIVATION 10 7.10e-01 -0.068000 8.87e-01
REACTOME FRUCTOSE METABOLISM 7 7.11e-01 -0.081000 8.87e-01
REACTOME MATURATION OF SARS COV 2 SPIKE PROTEIN 35 7.11e-01 0.036200 8.87e-01
REACTOME CYTOCHROME C MEDIATED APOPTOTIC RESPONSE 12 7.12e-01 0.061700 8.88e-01
REACTOME IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS 17 7.12e-01 0.051700 8.88e-01
REACTOME SHC1 EVENTS IN EGFR SIGNALING 14 7.13e-01 0.056900 8.88e-01
REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES 22 7.14e-01 0.045200 8.89e-01
REACTOME HSF1 DEPENDENT TRANSACTIVATION 37 7.15e-01 0.034700 8.89e-01
REACTOME EICOSANOIDS 12 7.17e-01 -0.060500 8.90e-01
REACTOME TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX 14 7.17e-01 0.056000 8.90e-01
REACTOME RHO GTPASES ACTIVATE PAKS 19 7.18e-01 0.047900 8.91e-01
REACTOME VASOPRESSIN LIKE RECEPTORS 5 7.20e-01 0.092700 8.92e-01
REACTOME REGULATION OF NPAS4 MRNA TRANSLATION 9 7.20e-01 -0.069000 8.92e-01
REACTOME DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS 25 7.22e-01 -0.041100 8.94e-01
REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS 43 7.23e-01 -0.031300 8.94e-01
REACTOME ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION 28 7.24e-01 0.038600 8.94e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1 20 7.24e-01 0.045700 8.94e-01
REACTOME CHYLOMICRON ASSEMBLY 10 7.25e-01 -0.064400 8.94e-01
REACTOME TIGHT JUNCTION INTERACTIONS 29 7.25e-01 -0.037700 8.94e-01
REACTOME MOLYBDENUM COFACTOR BIOSYNTHESIS 6 7.26e-01 -0.082500 8.95e-01
REACTOME EPHB MEDIATED FORWARD SIGNALING 41 7.27e-01 0.031500 8.95e-01
REACTOME DEPOLYMERISATION OF THE NUCLEAR LAMINA 14 7.29e-01 -0.053500 8.95e-01
REACTOME RHO GTPASES ACTIVATE CIT 19 7.30e-01 0.045800 8.95e-01
REACTOME METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION 15 7.30e-01 -0.051400 8.95e-01
REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE 15 7.31e-01 0.051400 8.95e-01
REACTOME ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING 23 7.31e-01 -0.041500 8.95e-01
REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES 77 7.31e-01 -0.022700 8.95e-01
REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS 17 7.31e-01 -0.048200 8.95e-01
REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY 15 7.32e-01 0.051100 8.95e-01
REACTOME RUNX3 REGULATES NOTCH SIGNALING 13 7.32e-01 -0.054900 8.95e-01
REACTOME DOPAMINE RECEPTORS 5 7.32e-01 0.088400 8.95e-01
REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING 30 7.34e-01 0.035900 8.96e-01
REACTOME INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE 20 7.34e-01 0.043900 8.96e-01
REACTOME RHOD GTPASE CYCLE 49 7.35e-01 -0.028000 8.96e-01
REACTOME NICOTINATE METABOLISM 31 7.37e-01 0.034900 8.98e-01
REACTOME ERK MAPK TARGETS 20 7.39e-01 -0.043100 8.99e-01
REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY 26 7.39e-01 -0.037800 8.99e-01
REACTOME RUNX3 REGULATES YAP1 MEDIATED TRANSCRIPTION 8 7.41e-01 -0.067400 9.02e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS 9 7.42e-01 -0.063400 9.02e-01
REACTOME REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS 7 7.44e-01 -0.071300 9.03e-01
REACTOME EARLY SARS COV 2 INFECTION EVENTS 34 7.45e-01 -0.032300 9.04e-01
REACTOME EGFR INTERACTS WITH PHOSPHOLIPASE C GAMMA 9 7.46e-01 -0.062200 9.04e-01
REACTOME INSULIN RECEPTOR RECYCLING 29 7.47e-01 0.034700 9.04e-01
REACTOME TYSND1 CLEAVES PEROXISOMAL PROTEINS 7 7.47e-01 -0.070500 9.04e-01
REACTOME ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS 87 7.52e-01 0.019600 9.10e-01
REACTOME SCAVENGING OF HEME FROM PLASMA 13 7.55e-01 -0.050000 9.13e-01
REACTOME ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS 11 7.56e-01 0.054200 9.13e-01
REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS 35 7.57e-01 -0.030200 9.14e-01
REACTOME SUMOYLATION OF INTRACELLULAR RECEPTORS 29 7.60e-01 0.032700 9.16e-01
REACTOME FGFR2 LIGAND BINDING AND ACTIVATION 19 7.61e-01 0.040300 9.16e-01
REACTOME RESPONSE TO METAL IONS 14 7.62e-01 -0.046800 9.16e-01
REACTOME RHOV GTPASE CYCLE 36 7.62e-01 0.029200 9.16e-01
REACTOME MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS 17 7.63e-01 -0.042300 9.16e-01
REACTOME AZATHIOPRINE ADME 22 7.63e-01 -0.037100 9.16e-01
REACTOME RET SIGNALING 40 7.63e-01 -0.027500 9.16e-01
REACTOME SENSORY PROCESSING OF SOUND 72 7.64e-01 0.020400 9.16e-01
REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX 8 7.65e-01 0.061100 9.16e-01
REACTOME DEFECTIVE CHST3 CAUSES SEDCJD 7 7.65e-01 -0.065300 9.16e-01
REACTOME FGFR1C LIGAND BINDING AND ACTIVATION 11 7.65e-01 0.052000 9.16e-01
REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION 23 7.68e-01 -0.035600 9.18e-01
REACTOME BETA CATENIN PHOSPHORYLATION CASCADE 16 7.68e-01 -0.042600 9.18e-01
REACTOME RETROGRADE NEUROTROPHIN SIGNALLING 14 7.68e-01 -0.045500 9.18e-01
REACTOME INTRA GOLGI TRAFFIC 43 7.69e-01 -0.025900 9.18e-01
REACTOME ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS 10 7.71e-01 -0.053200 9.20e-01
REACTOME STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES 16 7.72e-01 0.041900 9.20e-01
REACTOME REGULATION OF KIT SIGNALING 16 7.73e-01 0.041700 9.21e-01
REACTOME REGULATION OF NPAS4 GENE TRANSCRIPTION 5 7.73e-01 -0.074400 9.21e-01
REACTOME HEME SIGNALING 47 7.77e-01 -0.023900 9.24e-01
REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS 16 7.77e-01 0.040900 9.24e-01
REACTOME SIALIC ACID METABOLISM 33 7.78e-01 0.028300 9.24e-01
REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION 36 7.80e-01 0.026900 9.26e-01
REACTOME CATION COUPLED CHLORIDE COTRANSPORTERS 7 7.82e-01 0.060300 9.27e-01
REACTOME LYSOSOME VESICLE BIOGENESIS 33 7.83e-01 0.027700 9.27e-01
REACTOME LIGAND RECEPTOR INTERACTIONS 8 7.84e-01 0.056100 9.27e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX 91 7.84e-01 0.016600 9.27e-01
REACTOME G ALPHA S SIGNALLING EVENTS 155 7.85e-01 -0.012700 9.27e-01
REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION 10 7.85e-01 0.049800 9.27e-01
REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION 6 7.85e-01 0.064200 9.27e-01
REACTOME UREA CYCLE 9 7.86e-01 0.052400 9.27e-01
REACTOME PLASMA LIPOPROTEIN CLEARANCE 37 7.87e-01 -0.025600 9.29e-01
REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION 20 7.89e-01 0.034600 9.30e-01
REACTOME COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC 52 7.90e-01 0.021300 9.31e-01
REACTOME NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION 193 7.91e-01 0.011100 9.31e-01
REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS 8 7.93e-01 0.053600 9.31e-01
REACTOME SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER 54 7.93e-01 0.020600 9.31e-01
REACTOME NEPHRIN FAMILY INTERACTIONS 22 7.94e-01 -0.032100 9.31e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K 12 7.95e-01 0.043400 9.31e-01
REACTOME GAP JUNCTION TRAFFICKING AND REGULATION 49 7.95e-01 0.021500 9.31e-01
REACTOME LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME 11 7.95e-01 0.045200 9.31e-01
REACTOME TRANSPORT AND SYNTHESIS OF PAPS 6 7.95e-01 -0.061100 9.31e-01
REACTOME TP53 REGULATES METABOLIC GENES 81 7.95e-01 0.016700 9.31e-01
REACTOME INTERLEUKIN 35 SIGNALLING 12 7.97e-01 0.042800 9.32e-01
REACTOME BETA CATENIN INDEPENDENT WNT SIGNALING 145 7.98e-01 0.012300 9.32e-01
REACTOME TYROSINE CATABOLISM 5 7.98e-01 -0.066000 9.32e-01
REACTOME METALLOTHIONEINS BIND METALS 11 8.00e-01 -0.044200 9.32e-01
REACTOME BETA OXIDATION OF BUTANOYL COA TO ACETYL COA 5 8.01e-01 0.065100 9.32e-01
REACTOME BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA 5 8.01e-01 0.065000 9.32e-01
REACTOME PP2A MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS 6 8.01e-01 -0.059300 9.32e-01
REACTOME UPTAKE AND FUNCTION OF ANTHRAX TOXINS 11 8.02e-01 0.043700 9.32e-01
REACTOME PEPTIDE HORMONE METABOLISM 84 8.02e-01 -0.015800 9.32e-01
REACTOME N GLYCAN ANTENNAE ELONGATION 15 8.03e-01 0.037300 9.32e-01
REACTOME GAP JUNCTION ASSEMBLY 36 8.03e-01 0.024000 9.32e-01
REACTOME PHENYLALANINE AND TYROSINE METABOLISM 11 8.04e-01 -0.043300 9.32e-01
REACTOME IRAK4 DEFICIENCY TLR2 4 17 8.05e-01 -0.034600 9.34e-01
REACTOME RAP1 SIGNALLING 16 8.07e-01 -0.035300 9.35e-01
REACTOME SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL 25 8.09e-01 -0.028000 9.37e-01
REACTOME GRB2 EVENTS IN ERBB2 SIGNALING 16 8.10e-01 0.034700 9.37e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING 25 8.10e-01 -0.027700 9.37e-01
REACTOME TNFR1 INDUCED PROAPOPTOTIC SIGNALING 23 8.11e-01 0.028800 9.37e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES 33 8.12e-01 -0.023900 9.38e-01
REACTOME MTOR SIGNALLING 40 8.15e-01 -0.021400 9.38e-01
REACTOME RHO GTPASES ACTIVATE KTN1 11 8.15e-01 0.040700 9.38e-01
REACTOME REGULATION OF MECP2 EXPRESSION AND ACTIVITY 30 8.16e-01 0.024500 9.38e-01
REACTOME SYNAPTIC ADHESION LIKE MOLECULES 19 8.17e-01 0.030700 9.38e-01
REACTOME CHOLINE CATABOLISM 6 8.17e-01 -0.054500 9.38e-01
REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE 48 8.17e-01 -0.019300 9.38e-01
REACTOME STAT3 NUCLEAR EVENTS DOWNSTREAM OF ALK SIGNALING 9 8.18e-01 0.044400 9.38e-01
REACTOME ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS 24 8.18e-01 0.027100 9.38e-01
REACTOME RAF INDEPENDENT MAPK1 3 ACTIVATION 22 8.18e-01 0.028300 9.38e-01
REACTOME IRF3 MEDIATED INDUCTION OF TYPE I IFN 13 8.19e-01 0.036700 9.38e-01
REACTOME MISCELLANEOUS SUBSTRATES 12 8.19e-01 -0.038200 9.38e-01
REACTOME RSK ACTIVATION 5 8.19e-01 -0.059100 9.38e-01
REACTOME RND1 GTPASE CYCLE 41 8.20e-01 -0.020600 9.38e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN 21 8.20e-01 0.028600 9.38e-01
REACTOME HIV ELONGATION ARREST AND RECOVERY 33 8.23e-01 0.022600 9.40e-01
REACTOME RUNX3 REGULATES P14 ARF 10 8.25e-01 0.040400 9.42e-01
REACTOME DEATH RECEPTOR SIGNALING 143 8.26e-01 -0.010600 9.43e-01
REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION 9 8.29e-01 0.041500 9.44e-01
REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS 9 8.30e-01 -0.041300 9.44e-01
REACTOME ACYL CHAIN REMODELING OF CL 5 8.30e-01 0.055300 9.44e-01
REACTOME RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR 19 8.30e-01 -0.028400 9.44e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES 43 8.31e-01 0.018800 9.44e-01
REACTOME SIGNALING BY NOTCH2 32 8.31e-01 0.021800 9.44e-01
REACTOME REGULATED PROTEOLYSIS OF P75NTR 11 8.31e-01 0.037100 9.44e-01
REACTOME POLB DEPENDENT LONG PATCH BASE EXCISION REPAIR 8 8.32e-01 -0.043300 9.44e-01
REACTOME MAPK1 ERK2 ACTIVATION 9 8.32e-01 -0.040800 9.44e-01
REACTOME DISINHIBITION OF SNARE FORMATION 5 8.35e-01 -0.053800 9.44e-01
REACTOME SUMOYLATION OF DNA METHYLATION PROTEINS 16 8.35e-01 0.030000 9.44e-01
REACTOME NONCANONICAL ACTIVATION OF NOTCH3 8 8.35e-01 -0.042400 9.44e-01
REACTOME NTRK2 ACTIVATES RAC1 5 8.36e-01 -0.053500 9.44e-01
REACTOME PI METABOLISM 79 8.37e-01 -0.013400 9.44e-01
REACTOME ROBO RECEPTORS BIND AKAP5 9 8.38e-01 0.039400 9.44e-01
REACTOME CTLA4 INHIBITORY SIGNALING 21 8.38e-01 0.025800 9.44e-01
REACTOME VITAMIN C ASCORBATE METABOLISM 8 8.39e-01 -0.041500 9.44e-01
REACTOME GAP JUNCTION DEGRADATION 12 8.39e-01 0.033900 9.44e-01
REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM 23 8.39e-01 0.024500 9.44e-01
REACTOME CALCINEURIN ACTIVATES NFAT 9 8.39e-01 0.039100 9.44e-01
REACTOME REGULATION OF FZD BY UBIQUITINATION 21 8.40e-01 0.025500 9.44e-01
REACTOME DEFECTIVE CSF2RB CAUSES SMDP5 7 8.40e-01 0.044100 9.44e-01
REACTOME FBXW7 MUTANTS AND NOTCH1 IN CANCER 5 8.40e-01 0.052100 9.44e-01
REACTOME SIGNALING BY PDGF 57 8.41e-01 -0.015300 9.44e-01
REACTOME TRNA AMINOACYLATION 40 8.42e-01 0.018300 9.44e-01
REACTOME VEGFR2 MEDIATED CELL PROLIFERATION 19 8.43e-01 -0.026300 9.44e-01
REACTOME PROCESSING OF SMDT1 16 8.43e-01 -0.028600 9.44e-01
REACTOME SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX 15 8.45e-01 -0.029200 9.45e-01
REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 11 8.46e-01 0.033900 9.46e-01
REACTOME SMALL INTERFERING RNA SIRNA BIOGENESIS 9 8.48e-01 0.037000 9.47e-01
REACTOME ASPARTATE AND ASPARAGINE METABOLISM 11 8.49e-01 -0.033200 9.48e-01
REACTOME DECTIN 2 FAMILY 26 8.50e-01 -0.021400 9.49e-01
REACTOME MAP2K AND MAPK ACTIVATION 38 8.52e-01 -0.017500 9.49e-01
REACTOME IRON UPTAKE AND TRANSPORT 56 8.52e-01 0.014400 9.49e-01
REACTOME MITOCHONDRIAL TRNA AMINOACYLATION 20 8.53e-01 0.024000 9.49e-01
REACTOME NEF MEDIATED CD4 DOWN REGULATION 9 8.53e-01 0.035700 9.49e-01
REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND 21 8.53e-01 -0.023300 9.49e-01
REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION 9 8.54e-01 0.035500 9.49e-01
REACTOME DISEASES ASSOCIATED WITH SURFACTANT METABOLISM 9 8.54e-01 0.035400 9.49e-01
REACTOME PROPIONYL COA CATABOLISM 5 8.58e-01 -0.046400 9.52e-01
REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION 12 8.58e-01 0.029800 9.52e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FYN 7 8.59e-01 -0.038600 9.53e-01
REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX 85 8.62e-01 -0.010900 9.55e-01
REACTOME MULTIFUNCTIONAL ANION EXCHANGERS 9 8.62e-01 -0.033400 9.55e-01
REACTOME DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B 7 8.64e-01 0.037500 9.55e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS 8 8.64e-01 -0.035000 9.55e-01
REACTOME LDL REMODELING 6 8.66e-01 0.039800 9.57e-01
REACTOME AMYLOID FIBER FORMATION 102 8.68e-01 -0.009520 9.57e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES 29 8.68e-01 0.017800 9.57e-01
REACTOME FERTILIZATION 26 8.68e-01 -0.018800 9.57e-01
REACTOME DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE 17 8.69e-01 0.023100 9.57e-01
REACTOME PROLACTIN RECEPTOR SIGNALING 15 8.70e-01 -0.024400 9.57e-01
REACTOME SYNTHESIS OF GDP MANNOSE 5 8.70e-01 0.042100 9.57e-01
REACTOME MYOGENESIS 29 8.71e-01 -0.017500 9.57e-01
REACTOME METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS 122 8.71e-01 -0.008520 9.57e-01
REACTOME ERYTHROPOIETIN ACTIVATES STAT5 7 8.71e-01 0.035400 9.57e-01
REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES 34 8.72e-01 0.016000 9.57e-01
REACTOME STRIATED MUSCLE CONTRACTION 35 8.73e-01 -0.015600 9.58e-01
REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION 15 8.74e-01 0.023600 9.58e-01
REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS 8 8.75e-01 0.032100 9.58e-01
REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION 74 8.75e-01 -0.010500 9.58e-01
REACTOME SYNTHESIS OF PE 13 8.76e-01 -0.025100 9.58e-01
REACTOME TRANSPORT OF RCBL WITHIN THE BODY 8 8.76e-01 0.031700 9.58e-01
REACTOME TRAFFICKING OF AMPA RECEPTORS 29 8.77e-01 0.016600 9.58e-01
REACTOME SIGNALING BY RECEPTOR TYROSINE KINASES 507 8.79e-01 0.003930 9.59e-01
REACTOME POST TRANSCRIPTIONAL SILENCING BY SMALL RNAS 7 8.80e-01 -0.033000 9.59e-01
REACTOME SARS COV 2 MODULATES AUTOPHAGY 11 8.80e-01 -0.026300 9.59e-01
REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS 21 8.81e-01 0.018900 9.59e-01
REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK 17 8.81e-01 -0.021000 9.59e-01
REACTOME KINESINS 59 8.83e-01 -0.011000 9.60e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS 5 8.84e-01 0.037800 9.60e-01
REACTOME AMINO ACID CONJUGATION 9 8.84e-01 0.028200 9.60e-01
REACTOME SIGNALING BY NTRK2 TRKB 25 8.84e-01 0.016800 9.60e-01
REACTOME NADE MODULATES DEATH SIGNALLING 5 8.84e-01 0.037600 9.60e-01
REACTOME ANTIMICROBIAL PEPTIDES 76 8.86e-01 0.009540 9.60e-01
REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS 312 8.87e-01 0.004690 9.60e-01
REACTOME SIGNALING BY BMP 27 8.87e-01 0.015800 9.60e-01
REACTOME SIGNALING BY NOTCH3 48 8.88e-01 -0.011800 9.60e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL 14 8.89e-01 0.021600 9.60e-01
REACTOME INTRAFLAGELLAR TRANSPORT 50 8.89e-01 0.011400 9.60e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES 8 8.89e-01 0.028500 9.60e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH RAS 8 8.89e-01 -0.028400 9.60e-01
REACTOME LONG TERM POTENTIATION 22 8.92e-01 -0.016800 9.62e-01
REACTOME GLYCOSPHINGOLIPID METABOLISM 39 8.95e-01 -0.012200 9.65e-01
REACTOME HYALURONAN METABOLISM 17 8.96e-01 -0.018200 9.66e-01
REACTOME NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10 12 8.98e-01 0.021400 9.67e-01
REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX 14 8.98e-01 -0.019700 9.67e-01
REACTOME APEX1 INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY 7 9.00e-01 0.027400 9.67e-01
REACTOME G ALPHA Z SIGNALLING EVENTS 48 9.01e-01 0.010400 9.67e-01
REACTOME FORMATION OF PARAXIAL MESODERM 22 9.01e-01 -0.015300 9.67e-01
REACTOME SIGNALING BY MET 78 9.01e-01 -0.008110 9.67e-01
REACTOME ORGANIC ANION TRANSPORT 5 9.03e-01 -0.031500 9.68e-01
REACTOME RHOH GTPASE CYCLE 37 9.04e-01 0.011400 9.69e-01
REACTOME ERBB2 REGULATES CELL MOTILITY 15 9.04e-01 0.017900 9.69e-01
REACTOME NUCLEOTIDE CATABOLISM 35 9.07e-01 0.011500 9.69e-01
REACTOME TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS 52 9.07e-01 -0.009410 9.69e-01
REACTOME VEGF LIGAND RECEPTOR INTERACTIONS 7 9.10e-01 -0.024600 9.69e-01
REACTOME ACTIVATION OF CASPASES THROUGH APOPTOSOME MEDIATED CLEAVAGE 5 9.10e-01 0.029100 9.69e-01
REACTOME BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA 5 9.11e-01 0.028900 9.69e-01
REACTOME SERINE BIOSYNTHESIS 9 9.12e-01 0.021200 9.69e-01
REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS 16 9.14e-01 -0.015600 9.69e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS 15 9.14e-01 -0.016100 9.69e-01
REACTOME SLC TRANSPORTER DISORDERS 94 9.15e-01 0.006380 9.69e-01
REACTOME EPH EPHRIN SIGNALING 90 9.15e-01 -0.006510 9.69e-01
REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE 20 9.16e-01 -0.013700 9.69e-01
REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL 13 9.16e-01 0.016900 9.69e-01
REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES 14 9.17e-01 0.016100 9.69e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX 19 9.17e-01 0.013700 9.69e-01
REACTOME SIGNALING BY RNF43 MUTANTS 8 9.17e-01 0.021200 9.69e-01
REACTOME PHENYLALANINE METABOLISM 6 9.18e-01 -0.024400 9.69e-01
REACTOME SOS MEDIATED SIGNALLING 7 9.18e-01 0.022600 9.69e-01
REACTOME CGMP EFFECTS 16 9.19e-01 -0.014700 9.69e-01
REACTOME KILLING MECHANISMS 11 9.19e-01 0.017700 9.69e-01
REACTOME REGULATION OF PTEN GENE TRANSCRIPTION 59 9.19e-01 -0.007630 9.69e-01
REACTOME ACTIVATION OF PPARGC1A PGC 1ALPHA BY PHOSPHORYLATION 10 9.20e-01 0.018400 9.69e-01
REACTOME GPER1 SIGNALING 45 9.20e-01 -0.008600 9.69e-01
REACTOME PREGNENOLONE BIOSYNTHESIS 12 9.21e-01 0.016600 9.69e-01
REACTOME ALPHA OXIDATION OF PHYTANATE 6 9.21e-01 0.023500 9.69e-01
REACTOME OVARIAN TUMOR DOMAIN PROTEASES 36 9.22e-01 -0.009490 9.69e-01
REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE 11 9.22e-01 0.017100 9.69e-01
REACTOME SYNTHESIS OF LIPOXINS LX 6 9.22e-01 0.023100 9.69e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING 5 9.22e-01 0.025200 9.69e-01
REACTOME NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY 6 9.22e-01 0.023000 9.69e-01
REACTOME GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION 42 9.23e-01 0.008630 9.69e-01
REACTOME PASSIVE TRANSPORT BY AQUAPORINS 13 9.23e-01 0.015400 9.69e-01
REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES 7 9.23e-01 0.021000 9.69e-01
REACTOME PECAM1 INTERACTIONS 12 9.25e-01 0.015800 9.69e-01
REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX 39 9.25e-01 0.008740 9.69e-01
REACTOME SULFUR AMINO ACID METABOLISM 27 9.25e-01 0.010400 9.69e-01
REACTOME NUCLEAR SIGNALING BY ERBB4 32 9.26e-01 -0.009440 9.69e-01
REACTOME PLATELET HOMEOSTASIS 85 9.28e-01 -0.005660 9.71e-01
REACTOME PI3K AKT ACTIVATION 9 9.29e-01 -0.017200 9.71e-01
REACTOME ESTROGEN BIOSYNTHESIS 6 9.30e-01 -0.020600 9.71e-01
REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS 20 9.31e-01 0.011200 9.71e-01
REACTOME INTERLEUKIN RECEPTOR SHC SIGNALING 24 9.33e-01 -0.009860 9.73e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA 27 9.33e-01 -0.009280 9.73e-01
REACTOME CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER 25 9.37e-01 -0.009080 9.76e-01
REACTOME MET RECEPTOR ACTIVATION 6 9.38e-01 0.018400 9.76e-01
REACTOME BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA 6 9.38e-01 0.018300 9.76e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER 28 9.38e-01 0.008470 9.76e-01
REACTOME GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION 30 9.39e-01 0.008100 9.76e-01
REACTOME RHOBTB3 ATPASE CYCLE 8 9.40e-01 -0.015300 9.76e-01
REACTOME SIGNALING BY WNT IN CANCER 32 9.41e-01 -0.007550 9.77e-01
REACTOME PYRIMIDINE CATABOLISM 12 9.44e-01 -0.011800 9.79e-01
REACTOME CIRCADIAN CLOCK 68 9.47e-01 -0.004690 9.81e-01
REACTOME TRYPTOPHAN CATABOLISM 14 9.48e-01 0.010100 9.82e-01
REACTOME ABACAVIR ADME 9 9.49e-01 0.012400 9.82e-01
REACTOME RHO GTPASES ACTIVATE WASPS AND WAVES 34 9.50e-01 -0.006270 9.82e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE 11 9.52e-01 -0.010500 9.83e-01
REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV 1 INFECTION 5 9.53e-01 0.015400 9.83e-01
REACTOME TERMINAL PATHWAY OF COMPLEMENT 8 9.53e-01 0.012100 9.83e-01
REACTOME ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY 10 9.55e-01 0.010400 9.83e-01
REACTOME PENTOSE PHOSPHATE PATHWAY 12 9.55e-01 -0.009410 9.83e-01
REACTOME NEUREXINS AND NEUROLIGINS 51 9.56e-01 -0.004510 9.83e-01
REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS 45 9.56e-01 0.004720 9.83e-01
REACTOME AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY 8 9.56e-01 0.011100 9.83e-01
REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS 9 9.56e-01 -0.010500 9.83e-01
REACTOME EGFR TRANSACTIVATION BY GASTRIN 9 9.57e-01 -0.010500 9.83e-01
REACTOME FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS 8 9.58e-01 0.010700 9.83e-01
REACTOME CYTOSOLIC TRNA AMINOACYLATION 22 9.58e-01 -0.006430 9.83e-01
REACTOME PYRUVATE METABOLISM 29 9.59e-01 0.005480 9.83e-01
REACTOME RELEASE OF HH NP FROM THE SECRETING CELL 8 9.60e-01 -0.010200 9.83e-01
REACTOME SPHINGOLIPID METABOLISM 84 9.60e-01 -0.003140 9.83e-01
REACTOME PARASITE INFECTION 57 9.61e-01 -0.003770 9.83e-01
REACTOME DEVELOPMENTAL BIOLOGY 1115 9.61e-01 -0.000867 9.83e-01
REACTOME MICRORNA MIRNA BIOGENESIS 25 9.62e-01 -0.005560 9.83e-01
REACTOME MET ACTIVATES RAP1 AND RAC1 11 9.62e-01 -0.008380 9.83e-01
REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION 42 9.62e-01 0.004240 9.83e-01
REACTOME OPIOID SIGNALLING 89 9.63e-01 0.002850 9.83e-01
REACTOME ALPHA DEFENSINS 6 9.63e-01 -0.010900 9.83e-01
REACTOME CD163 MEDIATING AN ANTI INFLAMMATORY RESPONSE 9 9.65e-01 -0.008510 9.83e-01
REACTOME PTEN REGULATION 135 9.66e-01 0.002130 9.83e-01
REACTOME REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS 15 9.66e-01 0.006370 9.83e-01
REACTOME PHASE II CONJUGATION OF COMPOUNDS 102 9.66e-01 0.002410 9.83e-01
REACTOME ACYL CHAIN REMODELLING OF PI 17 9.67e-01 -0.005840 9.83e-01
REACTOME SIGNALING BY HIPPO 19 9.67e-01 -0.005450 9.83e-01
REACTOME DARPP 32 EVENTS 24 9.68e-01 -0.004700 9.84e-01
REACTOME FORMATION OF XYLULOSE 5 PHOSPHATE 5 9.69e-01 -0.010100 9.84e-01
REACTOME PHYSIOLOGICAL FACTORS 14 9.70e-01 -0.005880 9.84e-01
REACTOME LOSS OF FUNCTION OF SMAD2 3 IN CANCER 7 9.71e-01 0.007820 9.85e-01
REACTOME CHREBP ACTIVATES METABOLIC GENE EXPRESSION 8 9.72e-01 0.007110 9.85e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2 17 9.73e-01 -0.004830 9.85e-01
REACTOME RHOF GTPASE CYCLE 40 9.75e-01 -0.002860 9.87e-01
REACTOME NERVOUS SYSTEM DEVELOPMENT 552 9.77e-01 0.000712 9.88e-01
REACTOME DERMATAN SULFATE BIOSYNTHESIS 10 9.77e-01 0.005200 9.88e-01
REACTOME FCGR3A MEDIATED IL10 SYNTHESIS 36 9.77e-01 0.002730 9.88e-01
REACTOME SIGNALING BY NTRK3 TRKC 17 9.80e-01 -0.003540 9.90e-01
REACTOME RHOJ GTPASE CYCLE 51 9.82e-01 -0.001790 9.91e-01
REACTOME SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS 14 9.83e-01 0.003230 9.92e-01
REACTOME EICOSANOID LIGAND BINDING RECEPTORS 14 9.84e-01 -0.003120 9.92e-01
REACTOME PROTON COUPLED MONOCARBOXYLATE TRANSPORT 6 9.87e-01 0.003800 9.93e-01
REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN 15 9.88e-01 -0.002240 9.93e-01
REACTOME DEFECTIVE CHSY1 CAUSES TPBS 7 9.88e-01 -0.003260 9.93e-01
REACTOME BIOSYNTHESIS OF MARESINS 8 9.88e-01 0.002970 9.93e-01
REACTOME SIGNALING BY ALK 26 9.89e-01 -0.001590 9.93e-01
REACTOME CHYLOMICRON CLEARANCE 5 9.89e-01 0.003580 9.93e-01
REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES 29 9.89e-01 -0.001460 9.93e-01
REACTOME INSULIN PROCESSING 24 9.92e-01 -0.001190 9.95e-01
REACTOME EGFR DOWNREGULATION 30 9.92e-01 0.001010 9.95e-01
REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE 52 9.93e-01 0.000681 9.95e-01
REACTOME MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS 7 9.95e-01 -0.001430 9.95e-01
REACTOME SIGNALING BY EGFR 49 9.95e-01 -0.000537 9.95e-01
REACTOME PLATELET SENSITIZATION BY LDL 17 9.98e-01 -0.000423 9.98e-01


Detailed Gene set reports



REACTOME_METABOLISM_OF_RNA

REACTOME_METABOLISM_OF_RNA
1313
set REACTOME_METABOLISM_OF_RNA
setSize 675
pANOVA 2.44e-13
s.dist 0.165
p.adjustANOVA 4e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
PWP2 9896.0
LSM8 9812.0
POLR2J 9713.0
LENG1 9515.0
PSMB3 9424.0
CDC5L 9406.0
GTPBP3 9393.0
POM121 9376.0
SRSF7 9328.0
NHP2 9205.0
SDE2 9189.0
RBM8A 9122.0
RPS27A 9114.0
RRP9 9113.0
RTRAF 9084.0
SMN1 9067.5
SMN2 9067.5
METTL3 8944.0
NUDT21 8884.0
SMNDC1 8864.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PWP2 9896.0
LSM8 9812.0
POLR2J 9713.0
LENG1 9515.0
PSMB3 9424.0
CDC5L 9406.0
GTPBP3 9393.0
POM121 9376.0
SRSF7 9328.0
NHP2 9205.0
SDE2 9189.0
RBM8A 9122.0
RPS27A 9114.0
RRP9 9113.0
RTRAF 9084.0
SMN1 9067.5
SMN2 9067.5
METTL3 8944.0
NUDT21 8884.0
SMNDC1 8864.0
FAM32A 8836.0
RPL19 8794.0
SNRPA 8764.0
TRA2B 8698.0
RPL11 8697.0
SRSF10 8610.0
ADAR 8570.0
GEMIN6 8546.0
HNRNPU 8532.0
SNRPD1 8497.0
RPL37A 8477.0
PSMD12 8359.0
SYMPK 8342.0
MPHOSPH10 8311.0
RPLP1 8244.0
SF3B2 8224.0
PNO1 8208.0
PSMB2 8207.0
ERI1 8179.0
PPIH 8061.0
HSPB1 8046.0
PSME1 8043.0
CLP1 8035.0
TRMT1 8034.0
U2AF1L4 8031.0
RPSA 7996.0
UTP6 7866.0
SRSF8 7851.0
DDX39B 7841.0
CCNH 7837.0
SMG8 7818.0
NUP50 7809.0
NUP98 7806.0
LSM11 7805.0
RPS7 7771.0
SNRPF 7761.0
XPO1 7719.0
EXOSC3 7706.0
ZMAT2 7691.0
UPF1 7682.0
PSMB8 7596.0
RAE1 7570.0
RPL18 7565.0
LCMT2 7560.0
POLR2E 7472.0
GEMIN2 7468.0
FUS 7437.0
RPL35 7436.0
DNAJC8 7430.0
GTF2H3 7363.0
PRPF40A 7278.0
DIMT1 7207.0
APOBEC3A 7192.0
PSMB10 7164.0
PABPC1 7158.0
TRNT1 7076.0
RPL23 7060.0
CTU2 7025.0
PPP1R8 7024.0
SNRPC 7012.0
RPL7 6970.0
PATL1 6959.0
UBC 6955.0
ALYREF 6915.0
RPS15 6909.0
DCPS 6887.0
RPL26L1 6869.0
GTF2F1 6845.0
RPP40 6817.0
POLR2C 6815.0
RPS3A 6799.0
RPS19 6793.0
DDX39A 6712.0
U2SURP 6670.0
THOC1 6646.0
PSMD7 6526.0
PELP1 6511.0
SMU1 6483.0
PAIP1 6462.0
PCBP1 6452.0
ZNF830 6413.0
NT5C3B 6393.0
WDR43 6353.0
SF3A3 6309.0
PSMC2 6236.0
TRMT10A 6235.0
PSMB9 6207.0
NIP7 6189.0
APOBEC3B 6110.0
RPL5 6098.0
TRMT10C 6096.0
PABPN1 6091.0
CWC15 6058.0
RPL4 6052.0
HBS1L 6051.0
UBB 6050.0
SF3B6 6036.0
CACTIN 6032.0
IMP3 6015.0
PRCC 5988.0
UTP20 5971.0
DHX16 5960.0
TRMT61A 5941.0
RPL29 5923.0
CSTF1 5887.0
WDR36 5871.0
NUP43 5862.0
EXOSC1 5839.0
PCBP2 5838.0
NSRP1 5798.0
SNU13 5796.0
SNRNP35 5795.0
EPRS1 5787.0
RPS18 5767.0
RPS14 5716.0
RNPS1 5700.0
SRSF1 5683.0
BMS1 5671.0
WDR77 5654.0
PSMD5 5575.0
NOP58 5533.0
PSMD9 5509.0
DHX38 5488.0
FAU 5468.0
POLR2K 5445.0
RPP21 5437.0
HSPA8 5412.0
THOC3 5410.0
GEMIN5 5394.0
MAGOHB 5392.0
NOP2 5340.0
EIF4E 5333.0
EXOSC5 5326.0
NXF1 5306.0
CPSF6 5295.0
MAPKAPK2 5270.0
XPOT 5266.0
RPL12 5203.0
MRM1 5192.0
PPWD1 5191.0
RPP14 5182.0
DCAF13 5180.0
RPS3 5150.0
RBM7 5123.0
DDX20 5122.0
NSUN2 5111.0
ISG20L2 5046.0
CSNK1E 4963.0
PSMA7 4962.0
RPL36 4951.0
RPL7A 4944.0
RPL27 4926.0
BCAS2 4924.0
DDX46 4918.0
UPF3A 4844.0
RPL9 4842.0
POLR2D 4822.0
CNOT6L 4797.0
RPS26 4737.0
NUP35 4736.0
SNRNP27 4699.0
LSM3 4690.0
GNL3 4607.0
PSMA1 4589.0
EXOSC2 4588.0
RPL17 4586.0
TPRKB 4579.0
ZNF473 4578.0
RPS9 4570.0
TUT4 4562.0
PPP2R2A 4552.0
SMG5 4521.0
NAT10 4472.0
GSPT1 4461.0
GEMIN7 4441.0
SF3B5 4408.0
YWHAZ 4399.0
RPL15 4379.0
SMG7 4371.0
SNRPD2 4363.0
C2orf49 4324.0
TRMT61B 4288.0
CNOT9 4248.0
RPL31 4222.0
SRSF2 4219.0
PPP2CA 4197.0
USP39 4195.0
PUS7 4164.0
PSMD4 4162.0
SKIC8 4122.0
SRSF6 4086.0
HNRNPA2B1 4066.0
PUS1 4064.0
THUMPD1 4009.0
EXOSC4 4006.0
RPL24 4005.0
SRSF11 3999.0
PAPOLA 3964.0
PDCD7 3940.0
PSMD3 3937.0
RPS8 3907.0
FTSJ3 3885.0
XRN2 3863.0
PSME2 3849.0
FBL 3818.0
RIOK2 3762.0
RPS29 3760.0
SNW1 3749.0
NCL 3745.0
QTRT1 3744.0
PNN 3679.0
PPIL3 3664.0
NUP133 3541.0
YWHAB 3519.0
HNRNPD 3447.0
SRSF3 3435.0
ISY1 3431.0
ADAT3 3421.0
PPIG 3411.0
TP53RK 3375.0
CASC3 3359.0
RBM5 3289.0
DDX21 3273.0
CNOT3 3264.0
PSMC5 3212.0
MAGOH 3132.0
RPP30 3093.0
RRP36 3073.0
CPSF7 3055.0
ZBTB8OS 3052.0
RNMT 3008.0
ZFP36 3006.0
NUP85 2975.0
PSMA5 2972.0
KHSRP 2943.0
KRR1 2942.0
CPSF2 2928.0
PPIL2 2896.0
SRSF4 2891.0
IK 2890.0
LSM5 2888.0
RPL21 2851.0
NOP14 2847.0
PSMB4 2834.0
RPS2 2833.0
TNPO1 2826.0
RPS27L 2825.0
RPS6 2795.0
MTREX 2792.0
NUP58 2746.0
IGF2BP3 2730.0
QTRT2 2710.0
CPSF1 2683.0
RPS15A 2682.0
RPL3 2665.0
WDR3 2654.0
RBM25 2645.0
PSME3 2641.0
RPL18A 2635.0
RPLP2 2621.0
CDK7 2611.0
NUP107 2575.0
HNRNPA3 2535.0
TRMT112 2526.0
RPS5 2510.0
TYW3 2483.0
CWC22 2400.0
CPSF3 2377.0
HNRNPA1 2369.0
PSMA2 2366.0
MTO1 2342.0
RPS28 2309.0
HNRNPC 2272.0
NUP155 2265.0
NCBP2 2256.0
ADAT2 2213.0
HNRNPL 2196.0
PNRC2 2173.0
RPL35A 2159.0
RPS12 2017.0
UTP25 2014.0
ERCC3 2011.0
TYW5 1994.0
LUC7L3 1987.0
SARNP 1954.0
NDC1 1928.0
RPS16 1909.0
DCP2 1864.0
SF3A2 1844.0
CCDC12 1836.0
RPP38 1831.0
ZCRB1 1778.0
GCFC2 1733.0
SF1 1702.0
TSEN54 1673.0
RPS10 1666.0
RANBP2 1623.0
SNIP1 1569.0
SRSF12 1551.0
PRKCD 1540.0
THOC6 1537.0
RPL39L 1505.0
TXNL4A 1492.0
WBP11 1455.0
TCERG1 1391.0
SET 1320.0
DDX6 1308.0
NOL11 1294.0
SMG9 1269.0
RPL27A 1261.0
NOL12 1235.0
PPIL4 1217.0
TFIP11 1198.0
PLRG1 1197.0
CNOT2 1168.0
ACIN1 1138.0
MNAT1 1110.0
SMG6 1104.0
TSEN34 1084.0
SNRPD3 1055.0
FYTTD1 999.0
C9orf78 967.0
PSMC6 933.0
HNRNPF 914.0
PSMA3 884.0
TRMT13 842.0
PDCD11 792.0
RPL36AL 783.5
RPL3L 780.0
EMG1 773.0
NUP93 757.0
NOC4L 746.0
RIOK3 743.0
SLU7 730.0
APOBEC3C 721.0
PRPF4 713.0
RBM42 693.0
HNRNPK 657.0
RPL14 642.0
LSM2 606.0
GTF2H1 604.0
SEC13 551.0
BUD31 527.0
POM121C 523.0
NUP153 497.0
FCF1 490.0
CWC27 459.0
HSPA1A 453.0
UBA52 443.0
RPPH1 397.0
MAPK11 394.0
NUP88 349.0
RPL22 335.0
FIP1L1 322.0
NUP210 310.0
RRP1 282.0
EBNA1BP2 276.0
EIF4B 265.0
UPF2 232.0
PSMA6 176.0
RBM17 143.0
POP1 128.0
EXOSC9 99.0
PTBP1 86.0
DHX8 78.0
UTP11 59.0
PRPF3 49.0
BYSL 10.0
CLNS1A -49.0
LSM1 -87.0
ALKBH8 -91.0
TRMT5 -110.0
TEX10 -169.0
SUGP1 -185.0
DDX42 -238.0
DDX47 -249.0
SF3A1 -278.0
TSR3 -279.0
ZC3H11A -302.0
CNOT6 -332.0
RPS25 -336.0
TSR1 -337.0
SF3B4 -380.0
POP5 -401.0
SUPT5H -457.0
PRPF31 -523.0
SNRPG -533.0
TYW1 -563.0
CDC40 -602.0
NSUN6 -619.0
DIS3 -631.0
PES1 -642.0
RPLP0 -676.0
EIF4G1 -678.0
BUD23 -685.0
DDX49 -704.0
METTL14 -718.0
THOC7 -749.0
LTV1 -765.0
RBM39 -815.0
NUP188 -822.0
RPL6 -849.0
PSMD13 -945.0
TPR -967.0
SAP18 -985.0
EIF4A2 -993.0
SRSF5 -998.0
RPL10A -1071.0
NUP62 -1072.0
NCBP1 -1089.0
RBM28 -1096.0
NXT1 -1113.0
PRPF6 -1182.0
CNOT10 -1214.0
DHX35 -1222.0
WTAP -1237.0
XRN1 -1251.0
PSMB7 -1254.0
SRRT -1294.0
HNRNPM -1309.0
WDR70 -1338.0
IGF2BP2 -1364.0
POLR2I -1411.0
SLBP -1442.0
LSM4 -1511.0
RPS23 -1524.0
RPS27 -1537.0
WDR4 -1547.0
RPL10L -1553.0
PRKRIP1 -1570.0
CWF19L2 -1598.0
TRMT11 -1628.0
C1D -1646.0
SEH1L -1661.0
TRMT6 -1689.0
TSEN15 -1697.0
SNRPE -1701.0
RPS20 -1729.0
PPP2R1A -1758.0
TGS1 -1767.0
UTP15 -1768.0
DCP1A -1783.0
POP4 -1807.0
YBX1 -1821.0
GAR1 -1844.0
GTF2F2 -1855.0
NUP214 -1861.0
DUS2 -1867.0
PSMC1 -1911.0
RPS21 -1987.0
UBL5 -1995.0
SNUPN -2011.0
RNPC3 -2017.0
PCF11 -2051.0
NUP160 -2107.0
POLR2A -2108.0
EXOSC8 -2115.0
RNGTT -2153.0
GTF2H4 -2167.0
CCAR1 -2178.0
DDX1 -2220.0
LSM7 -2222.0
WBP4 -2263.0
PSMB1 -2266.0
SNRNP40 -2289.0
ZFP36L1 -2317.0
WDR75 -2362.0
SENP3 -2379.0
SNRNP70 -2390.0
SRRM1 -2414.0
SF3B1 -2443.0
METTL1 -2459.0
MAPK14 -2491.0
EFTUD2 -2498.0
EDC3 -2505.0
RPL13 -2515.0
UTP4 -2595.0
RPS24 -2603.0
RPL30 -2610.0
RPL34 -2744.0
WDR46 -2768.0
DCP1B -2786.0
NOB1 -2805.0
LSM6 -2885.0
AAAS -2886.0
CSTF2T -2890.0
THG1L -2961.0
PSMD1 -2969.0
EXOSC6 -2976.0
CHERP -3016.0
PSMD14 -3064.0
IGF2BP1 -3074.0
RPL8 -3092.0
DDX52 -3098.0
NUP205 -3107.0
PHF5A -3146.0
THOC5 -3161.0
PSMB6 -3169.0
SNRPN -3175.0
APOBEC3H -3176.0
OSGEP -3178.0
MTERF4 -3185.0
GPATCH1 -3196.0
SNRPA1 -3256.0
SF3B3 -3258.0
CNOT4 -3263.0
IMP4 -3367.0
PSMC4 -3386.0
SNRPB -3393.0
PRPF18 -3466.0
RPL32 -3472.0
ANP32A -3500.0
WDR18 -3517.0
PRPF19 -3518.0
RPS11 -3542.0
CHTOP -3569.0
UTP18 -3583.0
HEATR1 -3599.0
RPL37 -3656.0
GEMIN4 -3673.0
BUD13 -3696.0
BOP1 -3720.0
PSMB5 -3729.0
SYF2 -3767.0
PUS3 -3895.0
NUP54 -3926.0
CNOT7 -3994.0
POLR2G -4059.0
RCL1 -4067.0
SEM1 -4068.0
NSUN4 -4083.0
WDR33 -4088.0
PRORP -4234.0
PSME4 -4304.0
POLR2H -4306.0
SMG1 -4326.0
WDR12 -4327.0
RPL23A -4330.0
SNRPB2 -4342.0
RAN -4355.0
DHX15 -4368.0
POP7 -4434.0
HNRNPH1 -4495.0
RPL38 -4514.0
RIOK1 -4515.0
CTU1 -4546.0
CPSF4 -4580.0
SNRNP25 -4583.0
PAN2 -4636.0
CNOT1 -4686.0
THADA -4687.0
TRMT9B -4710.0
NOP10 -4814.0
NUP42 -4844.0
POLR2L -4867.0
TFB1M -4889.0
RPL28 -4919.0
SNRNP200 -4979.0
CDKAL1 -5012.0
EXOSC10 -5049.0
NOL9 -5074.0
PSMC3 -5134.0
UTP3 -5171.0
AQR -5178.0
FAM98B -5212.0
PSMD2 -5230.0
PSMD6 -5301.0
PSMA8 -5314.0
TNFSF13 -5334.0
MFAP1 -5345.0
SKIC2 -5390.0
PARN -5581.0
SRRM2 -5584.0
PHAX -5594.0
PRMT5 -5599.0
DDX41 -5604.0
EXOSC7 -5615.0
RPL41 -5644.0
RBM22 -5688.0
RPL22L1 -5689.0
DDX5 -5832.0
A1CF -5871.0
POLR2F -5909.0
XAB2 -5969.0
TRDMT1 -5999.0
ERCC2 -6042.0
YJU2 -6048.0
MPHOSPH6 -6074.0
DDX23 -6086.0
HNRNPR -6181.0
RTCB -6305.0
GTF2H5 -6365.0
ADARB1 -6396.0
PSMD8 -6475.0
NUP37 -6563.0
DHX37 -6648.0
ETF1 -6665.0
RPL13A -6787.5
EIF4A1 -6848.0
DHX9 -6860.0
CNOT11 -6912.0
LSM10 -7075.0
ADAT1 -7080.0
RPP25 -7097.0
PAN3 -7112.0
PRPF38A -7147.0
TUT7 -7176.0
ELAVL1 -7201.0
SART1 -7232.0
URM1 -7245.0
SKIC3 -7290.0
MRM3 -7292.0
EIF4A3 -7299.0
PPIL1 -7347.0
RPS13 -7476.0
POLR2B -7479.0
CNOT8 -7480.0
TRIT1 -7553.0
SRSF9 -7612.0
U2AF2 -7673.0
CRNKL1 -7760.0
PSMD11 -7848.0
CSTF3 -7860.0
PRPF8 -7897.0
RPL26 -8030.0
CWC25 -8074.0
AKT1 -8221.0
TSEN2 -8278.0
PRKCA -8381.0
GLE1 -8491.0
MRM2 -8549.0
EDC4 -8584.0
RRP7A -8632.0
PPIE -8813.0
NOP56 -8858.0
CSNK1D -8860.0
NOL6 -8924.0
TRMT12 -8964.0
POLDIP3 -9089.0
TBL3 -9266.0
PSMF1 -9271.0
TNKS1BP1 -9306.0
ELAC2 -9541.0
APOBEC4 -9552.0
APOBEC1 -9720.0
PUF60 -9798.0
UTP14C -10123.0
CTNNBL1 -10303.0
PSMA4 -10354.0
TRMU -10361.0
ZMAT5 -10511.0
TRMT44 -11027.0
PSMB11 -11028.0
SNRNP48 -11029.0
APOBEC2 -11559.0


REACTOME_OLFACTORY_SIGNALING_PATHWAY

REACTOME_OLFACTORY_SIGNALING_PATHWAY
628
set REACTOME_OLFACTORY_SIGNALING_PATHWAY
setSize 348
pANOVA 1.03e-09
s.dist -0.19
p.adjustANOVA 8.45e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
OR2S2 -11891
OR52E6 -11869
OR5K3 -11832
OR8I2 -11831
OR52E2 -11794
OR10J3 -11780
OR2D3 -11754
OR5T2 -11726
OR2G2 -11708
OR8B4 -11679
OR10S1 -11608
OR5AC2 -11599
OR5P2 -11598
OR13J1 -11587
OR2AE1 -11457
OR2A5 -11445
OR5H15 -11423
OR7A5 -11405
OR8H1 -11361
OR10G3 -11299

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
OR2S2 -11891.0
OR52E6 -11869.0
OR5K3 -11832.0
OR8I2 -11831.0
OR52E2 -11794.0
OR10J3 -11780.0
OR2D3 -11754.0
OR5T2 -11726.0
OR2G2 -11708.0
OR8B4 -11679.0
OR10S1 -11608.0
OR5AC2 -11599.0
OR5P2 -11598.0
OR13J1 -11587.0
OR2AE1 -11457.0
OR2A5 -11445.0
OR5H15 -11423.0
OR7A5 -11405.0
OR8H1 -11361.0
OR10G3 -11299.0
OR51I2 -11248.0
OR8B8 -11222.0
OR5H1 -11208.0
OR52D1 -11198.0
OR6C6 -11186.0
OR7D4 -11132.0
OR8D2 -11122.0
OR4K13 -11053.0
OR51V1 -11047.0
OR51G2 -10996.0
OR2M4 -10983.0
OR51Q1 -10949.0
OR51B6 -10947.0
OR8U1 -10934.0
OR4A47 -10917.0
OR52H1 -10868.0
OR2T6 -10861.0
OR52M1 -10838.0
OR6K6 -10822.0
OR1J4 -10817.0
OR10Z1 -10808.0
OR51I1 -10775.0
OR2D2 -10768.0
OR52A5 -10754.0
OR5C1 -10679.0
OR7A17 -10675.0
OR5B21 -10671.0
OR10T2 -10659.0
OR8A1 -10593.0
OR2AG2 -10546.0
OR6C74 -10540.0
OR14C36 -10499.0
OR52J3 -10496.0
OR6K3 -10482.0
OR2T33 -10478.0
OR8S1 -10458.0
OR9G4 -10445.0
OR4C46 -10384.0
OR9A2 -10339.0
OR2J2 -10324.0
OR51D1 -10245.0
OR8K5 -10232.0
OR10A6 -10203.0
OR52E4 -10108.0
OR5M11 -10044.0
OR13F1 -10013.0
OR10H2 -9961.0
OR6T1 -9936.0
OR2B11 -9930.0
OR1K1 -9916.0
OR2G6 -9888.0
CNGA4 -9837.0
OR4D11 -9802.0
OR10A4 -9799.0
OR4K5 -9705.0
OR4K17 -9689.0
OR13C3 -9647.0
OR3A2 -9531.0
OR7C2 -9513.0
OR10G7 -9503.0
OR2M5 -9434.0
OR5AU1 -9424.0
OR13C2 -9360.0
OR2Y1 -9359.0
OR6C3 -9325.0
OR13C8 -9295.0
OR8K3 -9262.0
OR6V1 -9259.0
OR1J1 -9231.0
OR51S1 -9206.0
OR13G1 -9051.0
OR6C68 -9039.0
OR6C2 -8938.0
OR5L1 -8917.0
OR4D10 -8862.0
OR51A2 -8844.0
OR12D2 -8805.0
OR6B2 -8798.0
OR10C1 -8771.0
OR10K1 -8758.0
OR1S1 -8704.0
OR11H6 -8692.0
OR7D2 -8675.0
OR5B12 -8645.0
OR8J1 -8610.0
OR4X1 -8586.0
OR6P1 -8585.0
OR6Y1 -8511.0
OR4D1 -8435.0
OR5J2 -8426.0
OR10AG1 -8393.0
OR8B12 -8377.0
OR10W1 -8186.0
OR10G2 -8167.0
OR1L1 -8006.0
OR14A16 -8005.0
CNGB1 -7943.0
EBF1 -7773.0
OR4D6 -7703.0
OR10A5 -7697.0
OR2C1 -7636.0
OR2T11 -7611.0
OR56B4 -7568.0
OR5M8 -7543.0
OR52E8 -7490.0
OR4N2 -7489.0
OR7A10 -7317.0
OR51E2 -7270.0
OR6C75 -7250.0
OR2C3 -7186.0
RTP2 -7172.0
OR6A2 -7088.0
OR4F15 -7055.0
OR1E2 -6899.0
OR3A3 -6843.0
OR52R1 -6839.0
OR51T1 -6835.0
OR2F1 -6813.0
OR51L1 -6690.0
OR10H1 -6582.0
OR1B1 -6431.0
OR8D4 -6425.0
OR2Z1 -6418.0
OR51B2 -6375.0
OR7C1 -6362.0
OR4C15 -6302.0
OR1N1 -6300.0
OR5K4 -6262.0
OR51A7 -6141.0
OR11H4 -6081.0
OR6X1 -6059.0
OR2L13 -6005.0
OR10A2 -5887.0
OR2V2 -5858.0
OR6F1 -5638.0
OR1I1 -5616.0
OR4A5 -5600.0
OR10V1 -5315.0
ANO2 -5284.0
OR2T4 -5204.0
OR5M9 -5189.0
OR5T1 -5117.0
OR6B3 -5100.0
OR2G3 -5050.0
OR52B6 -4948.0
OR3A1 -4903.0
OR4A16 -4837.0
OR13A1 -4812.0
OR7E24 -4702.0
OR9I1 -4638.0
OR14I1 -4615.0
OR51B5 -4600.0
OR2AG1 -4545.0
OR10J1 -4508.0
OR1A2 -4463.0
OR9G1 -4357.5
OR9G9 -4357.5
OR1C1 -4319.0
OR2B6 -4255.0
OR52I2 -4125.0
OR4X2 -4043.0
OR11G2 -3897.0
OR6K2 -3852.0
OR5A1 -3706.0
OR5K1 -3694.0
OR51G1 -3647.0
OR1G1 -3511.0
OR7G3 -3275.0
OR11L1 -3225.0
OR4A15 -3198.0
OR2T1 -3150.0
OR5V1 -3144.0
OR5M3 -3096.0
OR5P3 -3053.0
OR4S1 -2955.0
OR2A14 -2949.0
OR10A3 -2849.0
OR2F2 -2838.0
OR56A3 -2605.0
OR56A5 -2531.0
OR5D14 -2215.0
OR1N2 -2208.0
RTP1 -2204.0
OR8U8 -2159.0
OR4K14 -2105.0
OR1L8 -2042.0
OR10J5 -2040.0
OR1J2 -1896.0
ADCY3 -1857.0
OR52I1 -1819.0
OR8K1 -1801.0
OR2W3 -1682.0
OR52N1 -1601.0
OR2H1 -1466.0
OR2L5 -1392.0
OR1L3 -1351.0
OR52N2 -1342.0
OR2M7 -1319.0
OR1E1 -1196.0
OR6C70 -1131.0
OR4L1 -1039.0
OR11A1 -955.0
OR10X1 -902.0
OR6C65 -808.0
OR12D3 -794.0
OR6C76 -706.0
OR13C4 -674.0
OR10H3 -543.0
OR5AP2 -378.0
OR5D18 -196.0
OR5AK2 -189.0
OR4N5 -162.0
OR4C3 -158.0
OR52W1 -14.0
OR7G1 158.0
OR6B1 358.0
OR2B3 494.0
OR2T8 519.0
OR4B1 722.0
OR5H6 728.0
OR6M1 1158.0
OR8B2 1164.0
OR13C9 1429.0
OR4C45 1556.0
GNB1 1586.0
LDB1 1589.0
OR14J1 1624.0
OR2AT4 1650.0
OR4F6 1687.0
REEP1 1886.0
OR5I1 1933.0
OR7G2 1993.0
OR2L8 2034.0
OR1L4 2082.0
OR52A1 2259.0
OR5AS1 2345.0
OR2A2 2346.0
GNAL 2403.0
OR5L2 2424.0
OR5AN1 2604.0
OR5D13 2616.0
OR5B3 2653.0
OR4C12 2736.0
OR4K15 2763.0
OR8J3 2878.0
OR9K2 2903.0
OR1D2 2971.0
OR4C16 3150.0
OR10G9 3301.0
OR8D1 3378.0
OR4K1 3493.0
OR2L3 3524.0
OR51F2 3556.0
OR1A1 3672.0
OR10Q1 3707.0
OR5T3 3980.0
OR5B2 3983.0
OR51E1 4215.0
OR9Q1 4216.0
OR1M1 4368.0
OR5A2 4514.0
OR2W1 4546.0
LHX2 4840.0
OR5D16 5136.0
OR5M1 5230.0
OR4M1 5294.0
OR5F1 5427.0
OR2B2 5494.0
OR4C6 5593.0
OR5B17 5741.0
OR5AR1 5823.0
OR9A4 6165.0
OR6N2 6255.0
OR4K2 6356.0
OR5H2 6401.0
OR5K2 6465.0
OR10K2 6516.0
OR10G8 6656.0
OR6S1 6740.0
OR2V1 6782.0
OR9Q2 6851.0
OR10G4 6892.0
OR5W2 6910.0
OR2A12 7018.0
OR1L6 7089.0
OR2L2 7107.0
OR56A4 7129.0
OR2M2 7131.0
OR4D2 7165.0
OR13D1 7400.0
OR2T27 7407.0
OR2AK2 7492.0
OR10P1 7665.0
GNG13 8123.0
OR6C4 8158.0
OR4D5 8249.0
OR52K1 8286.0
OR52K2 8295.0
OR5M10 8408.0
OR51M1 8423.0
OR1S2 8699.0
OR8G1 8721.0
OR8U3 8753.0
OR51B4 8790.0
OR51F1 8805.0
OR56B1 8913.0
OR10H4 8928.0
OR52L1 9013.0
OR1F1 9137.0
OR6C1 9141.0
OR1Q1 9162.0
OR2K2 9261.0
OR52B2 9264.0
OR4D9 9286.0
OR56A1 9303.0
OR10H5 9326.0
OR10AD1 9346.0
OR2H2 9349.0
OR8G5 9367.0
OR2AP1 9409.0
OR2T12 9524.0
OR4E2 9696.0
OR2M3 9816.0
OR6N1 9912.0
OR8H3 9915.0
OR6Q1 9949.0
OR2T3 9982.0
OR10A7 9986.0


REACTOME_TRANSLATION

REACTOME_TRANSLATION
1152
set REACTOME_TRANSLATION
setSize 278
pANOVA 2.31e-09
s.dist 0.208
p.adjustANOVA 1.27e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
CHCHD1 9677
FARSA 9562
TUFM 9492
MRPL52 9417
MTIF2 9272
MRPL16 9251
ERAL1 9250
SEC61G 9125
RPS27A 9114
EEF1A2 9064
SEC61B 8900
MRPL53 8876
EEF1G 8866
MTFMT 8829
MARS2 8828
RPL19 8794
TRAM1 8769
MRPL33 8749
RPL11 8697
RPL37A 8477

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CHCHD1 9677.0
FARSA 9562.0
TUFM 9492.0
MRPL52 9417.0
MTIF2 9272.0
MRPL16 9251.0
ERAL1 9250.0
SEC61G 9125.0
RPS27A 9114.0
EEF1A2 9064.0
SEC61B 8900.0
MRPL53 8876.0
EEF1G 8866.0
MTFMT 8829.0
MARS2 8828.0
RPL19 8794.0
TRAM1 8769.0
MRPL33 8749.0
RPL11 8697.0
RPL37A 8477.0
SEC11A 8277.0
RPLP1 8244.0
MRPL36 8197.0
SRP54 8069.0
AIMP1 8054.0
EIF3K 8049.0
RPSA 7996.0
SRP72 7958.0
MRPL44 7826.0
TSFM 7799.0
RPS7 7771.0
MRPS18C 7742.0
MRPS24 7723.0
MRPS18B 7627.0
RPL18 7565.0
MRPL9 7515.0
MRPS26 7497.0
EIF3I 7471.0
RPL35 7436.0
RPN1 7418.0
MRPS15 7293.0
EIF3F 7259.0
PABPC1 7158.0
MRPL14 7082.0
RPL23 7060.0
RPL7 6970.0
EIF2B1 6961.0
RPS15 6909.0
RPL26L1 6869.0
MRPL28 6801.0
RPS3A 6799.0
RPS19 6793.0
EIF3J 6634.0
NARS2 6467.0
MRPL20 6297.0
MRPS7 6220.0
MRPL15 6204.0
MRPL10 6186.0
MRPS14 6107.0
MRPL42 6104.0
RPL5 6098.0
IARS1 6084.0
RPL4 6052.0
GADD45GIP1 5970.0
EIF2B2 5965.0
RPL29 5923.0
EPRS1 5787.0
RPS18 5767.0
RPS14 5716.0
MRPL48 5684.0
SPCS1 5677.0
FAU 5468.0
SRP68 5351.0
EIF4E 5333.0
MRPL40 5324.0
RPL12 5203.0
RPS3 5150.0
MRPS18A 5050.0
MRPL32 4986.0
RPL36 4951.0
RPL7A 4944.0
EIF5B 4928.0
RPL27 4926.0
PPA1 4856.0
RPL9 4842.0
SRP9 4778.0
RPS26 4737.0
MRPS10 4654.0
RPL17 4586.0
RPS9 4570.0
MRPL51 4469.0
GSPT1 4461.0
RPL15 4379.0
MRPS11 4357.0
MRPL41 4224.0
RPL31 4222.0
MRPL17 4187.0
SSR1 4085.0
MRPL57 4030.0
RPL24 4005.0
RPS8 3907.0
MRPL4 3824.0
AIMP2 3799.0
RPS29 3760.0
VARS2 3677.0
IARS2 3589.0
MRPL54 3583.0
MRPL13 3577.0
MRPL35 3407.0
TARS2 3395.0
MRPS21 3159.0
MRPS12 3133.0
MRPS23 3070.0
EEF1B2 3063.0
EARS2 3039.0
EIF3L 3031.0
SRP14 2853.0
RPL21 2851.0
RPS2 2833.0
RPS27L 2825.0
RPS6 2795.0
PTCD3 2694.0
RPS15A 2682.0
RPL3 2665.0
RPL18A 2635.0
RPLP2 2621.0
TRMT112 2526.0
RPS5 2510.0
EIF3M 2360.0
RPS28 2309.0
SRP19 2279.0
RPL35A 2159.0
SARS2 2108.0
MRPL24 2064.0
MTIF3 2050.0
RPS12 2017.0
MRPL38 2004.0
MRPL49 2002.0
MRRF 1982.0
GFM1 1976.0
MRPL34 1930.0
RPS16 1909.0
RPS10 1666.0
RPL39L 1505.0
SPCS3 1421.0
AURKAIP1 1375.0
MRPL19 1264.0
RPL27A 1261.0
MRPS31 1092.0
MRPS9 1072.0
KARS1 1015.0
LARS1 994.0
MRPL50 919.0
RPN2 867.0
VARS1 860.0
SEC61A1 794.0
MRPL18 793.0
RPL36AL 783.5
RPL3L 780.0
EIF2S1 647.0
RPL14 642.0
MRPL55 550.0
UBA52 443.0
PPA2 365.0
RPL22 335.0
EIF4B 265.0
SSR2 209.0
EIF2B4 182.0
MRPL45 111.0
MRPL2 76.0
EEF1A1 -41.0
SSR3 -250.0
EIF3G -321.0
RPS25 -336.0
DARS1 -362.0
SEC11C -505.0
RPLP0 -676.0
EIF4G1 -678.0
MRPS22 -694.0
RARS2 -814.0
RPL6 -849.0
DDOST -959.0
AARS1 -988.0
EIF4A2 -993.0
RPL10A -1071.0
CARS2 -1076.0
HARS1 -1102.0
MRPL30 -1128.0
WARS2 -1135.0
GFM2 -1265.0
SRPRA -1346.0
MRPL1 -1391.0
MRPL39 -1462.0
RPS23 -1524.0
RPS27 -1537.0
MRPL37 -1538.0
RPL10L -1553.0
APEH -1581.0
EIF2S2 -1726.0
RPS20 -1729.0
RPS21 -1987.0
PARS2 -2068.0
EIF3B -2175.0
DARS2 -2176.0
EIF3E -2232.0
FARSB -2482.0
MRPL22 -2488.0
RPL13 -2515.0
RPS24 -2603.0
RPL30 -2610.0
MRPS17 -2619.0
SPCS2 -2706.0
EIF2B5 -2734.0
RPL34 -2744.0
MTRF1L -2916.0
EIF3H -3036.0
MRPL3 -3083.0
RPL8 -3092.0
MRPS35 -3279.0
MRPS25 -3332.0
MRPS2 -3374.0
EIF4EBP1 -3380.0
MRPL46 -3392.0
RPL32 -3472.0
OXA1L -3527.0
EIF2B3 -3534.0
RPS11 -3542.0
YARS1 -3619.0
RPL37 -3656.0
HARS2 -3933.0
MRPS27 -3938.0
MRPS34 -4035.0
NARS1 -4206.0
EIF3A -4228.0
RPL23A -4330.0
MRPL21 -4352.0
EIF3D -4465.0
RPL38 -4514.0
MRPS16 -4721.0
MRPL12 -4817.0
RPL28 -4919.0
MRPS28 -5027.0
DAP3 -5039.0
MRPS30 -5059.0
WARS1 -5127.0
EEF1E1 -5133.0
EIF4H -5135.0
RPL41 -5644.0
RPL22L1 -5689.0
TARS1 -5719.0
EIF5 -5722.0
YARS2 -5901.0
LARS2 -6085.0
MRPS33 -6109.0
EEF2 -6120.0
FARS2 -6356.0
ETF1 -6665.0
RPL13A -6787.5
EIF4A1 -6848.0
GARS1 -7149.0
RARS1 -7239.0
RPS13 -7476.0
MRPS6 -7711.0
RPL26 -8030.0
EEF1D -8406.0
N6AMT1 -8678.0
MRPL23 -8687.0
MRPL58 -8802.0
MRPL43 -8872.0
AARS2 -8874.0
SEC61A2 -8925.0
MRPL11 -9327.0
CARS1 -9557.0
SRPRB -9655.0
MRPL47 -9719.0
MRPL27 -9786.0
MARS1 -10080.0
MRPS5 -10151.0


REACTOME_SENSORY_PERCEPTION

REACTOME_SENSORY_PERCEPTION
1581
set REACTOME_SENSORY_PERCEPTION
setSize 555
pANOVA 5.35e-09
s.dist -0.145
p.adjustANOVA 2.2e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
OR2S2 -11891
OR52E6 -11869
OR5K3 -11832
OR8I2 -11831
OR52E2 -11794
OR10J3 -11780
OR2D3 -11754
OR5T2 -11726
OR2G2 -11708
OR8B4 -11679
OR10S1 -11608
OR5AC2 -11599
OR5P2 -11598
OR13J1 -11587
TAS2R46 -11505
RDH5 -11493
OR2AE1 -11457
TAS2R41 -11447
OR2A5 -11445
OR5H15 -11423

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
OR2S2 -11891.0
OR52E6 -11869.0
OR5K3 -11832.0
OR8I2 -11831.0
OR52E2 -11794.0
OR10J3 -11780.0
OR2D3 -11754.0
OR5T2 -11726.0
OR2G2 -11708.0
OR8B4 -11679.0
OR10S1 -11608.0
OR5AC2 -11599.0
OR5P2 -11598.0
OR13J1 -11587.0
TAS2R46 -11505.0
RDH5 -11493.0
OR2AE1 -11457.0
TAS2R41 -11447.0
OR2A5 -11445.0
OR5H15 -11423.0
OR7A5 -11405.0
OR8H1 -11361.0
OR10G3 -11299.0
APOA4 -11283.0
OR51I2 -11248.0
OR8B8 -11222.0
OR5H1 -11208.0
OR52D1 -11198.0
OR6C6 -11186.0
HSD17B1 -11172.0
OR7D4 -11132.0
OR8D2 -11122.0
TAS2R7 -11054.0
OR4K13 -11053.0
OR51V1 -11047.0
OR51G2 -10996.0
OR2M4 -10983.0
TAS2R14 -10969.0
OR51Q1 -10949.0
OR51B6 -10947.0
OR8U1 -10934.0
OR4A47 -10917.0
GRK7 -10904.0
OR52H1 -10868.0
OR2T6 -10861.0
TTR -10853.0
OR52M1 -10838.0
OR6K6 -10822.0
OR1J4 -10817.0
OR10Z1 -10808.0
OR51I1 -10775.0
OR2D2 -10768.0
OR52A5 -10754.0
OR5C1 -10679.0
OR7A17 -10675.0
OR5B21 -10671.0
CHRNA9 -10666.0
OR10T2 -10659.0
SDR9C7 -10640.0
CALHM3 -10621.0
OR8A1 -10593.0
TAS2R10 -10592.0
OR2AG2 -10546.0
TAS1R3 -10545.0
OR6C74 -10540.0
OR14C36 -10499.0
OR52J3 -10496.0
OR6K3 -10482.0
OR2T33 -10478.0
TAS2R30 -10468.0
OR8S1 -10458.0
OR9G4 -10445.0
OR4C46 -10384.0
OR9A2 -10339.0
TAS2R8 -10332.0
OR2J2 -10324.0
RLBP1 -10260.0
OR51D1 -10245.0
OR8K5 -10232.0
OR10A6 -10203.0
OR52E4 -10108.0
OR5M11 -10044.0
MYO15A -10033.0
OR13F1 -10013.0
OR10H2 -9961.0
RBP2 -9943.0
OR6T1 -9936.0
OR2B11 -9930.0
OR1K1 -9916.0
OR2G6 -9888.0
RHO -9883.0
CNGA4 -9837.0
OR4D11 -9802.0
OR10A4 -9799.0
LRP8 -9732.0
OR4K5 -9705.0
SCNN1D -9693.0
OR4K17 -9689.0
OR13C3 -9647.0
KCNJ2 -9542.0
OR3A2 -9531.0
OR7C2 -9513.0
OR10G7 -9503.0
OR2M5 -9434.0
OR5AU1 -9424.0
OR13C2 -9360.0
OR2Y1 -9359.0
OR6C3 -9325.0
OR13C8 -9295.0
OR8K3 -9262.0
OR6V1 -9259.0
OR1J1 -9231.0
TWF2 -9229.0
CAPZA2 -9218.0
OR51S1 -9206.0
OR13G1 -9051.0
OR6C68 -9039.0
SLC24A1 -9014.0
FNTB -9009.0
ITPR3 -8994.0
OR6C2 -8938.0
OR5L1 -8917.0
OR4D10 -8862.0
OR51A2 -8844.0
OTOG -8816.0
OR12D2 -8805.0
OR6B2 -8798.0
TAS2R4 -8778.0
OR10C1 -8771.0
OR10K1 -8758.0
OR1S1 -8704.0
AKR1B10 -8703.0
OR11H6 -8692.0
HSPG2 -8681.0
OR7D2 -8675.0
OR5B12 -8645.0
OR8J1 -8610.0
OR4X1 -8586.0
OR6P1 -8585.0
OR6Y1 -8511.0
OR4D1 -8435.0
OR5J2 -8426.0
OR10AG1 -8393.0
PRKCA -8381.0
OR8B12 -8377.0
OR10W1 -8186.0
OR10G2 -8167.0
SCNN1A -8134.0
PDE6A -8127.0
OR1L1 -8006.0
OR14A16 -8005.0
TAS1R2 -7994.0
CNGB1 -7943.0
APOC3 -7884.0
GNAT3 -7789.0
RCVRN -7777.0
EBF1 -7773.0
OR4D6 -7703.0
OR10A5 -7697.0
OR2C1 -7636.0
APOA1 -7619.0
OR2T11 -7611.0
OR56B4 -7568.0
OR5M8 -7543.0
SDC2 -7524.0
CABP2 -7523.0
OR52E8 -7490.0
OR4N2 -7489.0
APOM -7326.0
OR7A10 -7317.0
STRC -7284.0
OR51E2 -7270.0
OR6C75 -7250.0
OR2C3 -7186.0
RTP2 -7172.0
OR6A2 -7088.0
KCNMA1 -7057.0
OR4F15 -7055.0
SCN3A -6975.0
GPC6 -6909.0
OR1E2 -6899.0
TAS2R38 -6858.0
OR3A3 -6843.0
OR52R1 -6839.0
OR51T1 -6835.0
OR2F1 -6813.0
NMT1 -6789.0
SNAP25 -6741.0
OR51L1 -6690.0
CAPZB -6607.0
OR10H1 -6582.0
ATP2B1 -6561.0
NAPEPLD -6494.0
PLB1 -6476.0
AKR1C4 -6444.0
OR1B1 -6431.0
SLC17A8 -6429.0
OR8D4 -6425.0
OR2Z1 -6418.0
CALHM1 -6408.0
OR51B2 -6375.0
OR7C1 -6362.0
LRP1 -6340.0
ATP2B2 -6334.0
CACNA2D2 -6330.0
OR4C15 -6302.0
OR1N1 -6300.0
OR5K4 -6262.0
OR51A7 -6141.0
USH1G -6121.0
OR11H4 -6081.0
OR6X1 -6059.0
RBP3 -6055.0
OR2L13 -6005.0
CABP1 -5916.0
PCLO -5897.0
OR10A2 -5887.0
OR2V2 -5858.0
OR6F1 -5638.0
OR1I1 -5616.0
OR4A5 -5600.0
LRP12 -5589.0
CLPS -5530.0
CIB2 -5524.0
OPN1SW -5386.0
BSN -5383.0
CACNB2 -5341.0
OR10V1 -5315.0
ANO2 -5284.0
FNTA -5228.0
OR2T4 -5204.0
OR5M9 -5189.0
SCN2B -5159.0
OR5T1 -5117.0
OR6B3 -5100.0
PLS1 -5081.0
OR2G3 -5050.0
CTBP2 -5042.0
OR52B6 -4948.0
OR3A1 -4903.0
OR4A16 -4837.0
OR13A1 -4812.0
CACNA1D -4773.0
OR7E24 -4702.0
OR9I1 -4638.0
OR14I1 -4615.0
OR51B5 -4600.0
SAG -4562.0
OR2AG1 -4545.0
OR10J1 -4508.0
OR1A2 -4463.0
BCO1 -4453.0
TAS2R43 -4389.0
OR9G1 -4357.5
OR9G9 -4357.5
GPC1 -4354.0
OR1C1 -4319.0
OR2B6 -4255.0
GSN -4240.0
GPIHBP1 -4238.0
PDE6B -4164.0
OR52I2 -4125.0
OR4X2 -4043.0
APOA2 -4018.0
OR11G2 -3897.0
USH1C -3863.0
SPTBN1 -3861.0
OR6K2 -3852.0
GRK4 -3768.0
OR5A1 -3706.0
OR5K1 -3694.0
OR51G1 -3647.0
OR1G1 -3511.0
CLIC5 -3484.0
TAS1R1 -3433.0
PRKCQ -3299.0
CHRNA10 -3298.0
OR7G3 -3275.0
OR11L1 -3225.0
OR4A15 -3198.0
OR2T1 -3150.0
KCNN2 -3145.0
OR5V1 -3144.0
OR5M3 -3096.0
CDH23 -3078.0
OR5P3 -3053.0
GPC5 -3045.0
RBP1 -3005.0
OR4S1 -2955.0
OR2A14 -2949.0
GNB5 -2946.0
OR10A3 -2849.0
RETSAT -2846.0
OR2F2 -2838.0
SCNN1B -2824.0
LRAT -2791.0
ESPNL -2777.0
TRIOBP -2761.0
CNGA1 -2719.0
RPE65 -2701.0
OR56A3 -2605.0
OR56A5 -2531.0
TMC1 -2322.0
NMT2 -2271.0
CALM1 -2269.0
OR5D14 -2215.0
OR1N2 -2208.0
RTP1 -2204.0
OR8U8 -2159.0
TAS2R20 -2148.0
GRM1 -2106.0
OR4K14 -2105.0
OR1L8 -2042.0
OR10J5 -2040.0
ACTG1 -1934.0
OR1J2 -1896.0
ADCY3 -1857.0
OR52I1 -1819.0
OR8K1 -1801.0
EZR -1765.0
OR2W3 -1682.0
MYO1C -1672.0
OR52N1 -1601.0
MYH9 -1576.0
OR2H1 -1466.0
OR2L5 -1392.0
OR1L3 -1351.0
OR52N2 -1342.0
OR2M7 -1319.0
OR1E1 -1196.0
GUCY2D -1133.0
OR6C70 -1131.0
SCN2A -1057.0
OR4L1 -1039.0
OR11A1 -955.0
OR10X1 -902.0
LPL -864.0
EPB41L1 -820.0
OR6C65 -808.0
OR12D3 -794.0
GNGT1 -733.0
OR6C76 -706.0
OR13C4 -674.0
PDE6G -671.0
EPB41L3 -664.0
PJVK -656.0
HSD17B6 -559.0
OR10H3 -543.0
MYO3B -435.0
CAPZA1 -421.0
TRPM4 -400.0
OR5AP2 -378.0
SCN9A -365.0
GUCA1C -313.0
OR5D18 -196.0
OR5AK2 -189.0
OR4N5 -162.0
OR4C3 -158.0
LRP10 -120.0
OR52W1 -14.0
SCNN1G 17.0
SDC1 63.0
TAS2R5 148.0
OR7G1 158.0
OR6B1 358.0
XIRP2 362.0
OR2B3 494.0
OR2T8 519.0
EPS8 525.0
OR4B1 722.0
OR5H6 728.0
METAP2 786.0
OTOGL 938.0
RDX 949.0
OR6M1 1158.0
OR8B2 1164.0
TAS2R31 1188.0
OR13C9 1429.0
OR4C45 1556.0
RIPOR2 1557.0
GNB1 1586.0
LDB1 1589.0
OR14J1 1624.0
OR2AT4 1650.0
OR4F6 1687.0
PLCB2 1717.0
RDH11 1872.0
REEP1 1886.0
OR5I1 1933.0
OR7G2 1993.0
OR2L8 2034.0
SDC4 2079.0
OR1L4 2082.0
OTOF 2109.0
APOC2 2151.0
BCO2 2170.0
ABCA4 2171.0
OR52A1 2259.0
LRRC52 2268.0
OR5AS1 2345.0
OR2A2 2346.0
GNAL 2403.0
MYO7A 2409.0
OR5L2 2424.0
RBP4 2442.0
GRM4 2516.0
OR5AN1 2604.0
SCN4B 2614.0
OR5D13 2616.0
OR5B3 2653.0
DHRS3 2716.0
OR4C12 2736.0
OR4K15 2763.0
OR8J3 2878.0
PCDH15 2897.0
OR9K2 2903.0
OR1D2 2971.0
OR4C16 3150.0
OR10G9 3301.0
WHRN 3339.0
OR8D1 3378.0
TAS2R1 3380.0
GUCA1A 3386.0
OR4K1 3493.0
OR2L3 3524.0
OR51F2 3556.0
TAS2R50 3606.0
OR1A1 3672.0
AKR1C3 3687.0
OR10Q1 3707.0
TRPM5 3803.0
VAMP2 3873.0
APOB 3896.0
OR5T3 3980.0
OR5B2 3983.0
LDLR 4011.0
SLC26A5 4033.0
OR51E1 4215.0
OR9Q1 4216.0
LRP2 4218.0
GRXCR2 4235.0
OR1M1 4368.0
RDH8 4413.0
CAMKMT 4436.0
MYO3A 4446.0
OR5A2 4514.0
TPRN 4540.0
OR2W1 4546.0
AKR1C1 4672.0
GNB3 4838.0
LHX2 4840.0
METAP1 4994.0
GUCA1B 5024.0
OR5D16 5136.0
OR5M1 5230.0
OR4M1 5294.0
OR5F1 5427.0
OR2B2 5494.0
GRK1 5588.0
OR4C6 5593.0
SPTAN1 5720.0
SCN1B 5738.0
OR5B17 5741.0
AGRN 5753.0
OR5AR1 5823.0
TWF1 5870.0
RAB3A 5872.0
GPC2 5925.0
STRA6 5981.0
TAS2R3 5997.0
CYP4V2 6130.0
OR9A4 6165.0
RGS9 6195.0
RDH10 6206.0
OR6N2 6255.0
KCNQ4 6285.0
OR4K2 6356.0
OR5H2 6401.0
OR5K2 6465.0
OR10K2 6516.0
GRXCR1 6530.0
EPS8L2 6538.0
OR10G8 6656.0
APOE 6687.0
FSCN2 6735.0
OR6S1 6740.0
TAS2R16 6765.0
OR2V1 6782.0
OR9Q2 6851.0
GNAT1 6881.0
OR10G4 6892.0
OR5W2 6910.0
OR2A12 7018.0
OR1L6 7089.0
OR2L2 7107.0
OR56A4 7129.0
OR2M2 7131.0
OR4D2 7165.0
DHRS9 7171.0
OR13D1 7400.0
OR2T27 7407.0
ESPN 7456.0
OR2AK2 7492.0
OR10P1 7665.0
LHFPL5 7790.0
RDH12 7855.0
OTOP1 7941.0
GNG13 8123.0
OR6C4 8158.0
PNLIP 8172.0
TMC2 8230.0
OR4D5 8249.0
TAS2R13 8265.0
OR52K1 8286.0
OR52K2 8295.0
DNAJC5 8296.0
OR5M10 8408.0
OR51M1 8423.0
STX1A 8617.0
RGS9BP 8643.0
OR1S2 8699.0
OR8G1 8721.0
OR8U3 8753.0
OR51B4 8790.0
OR51F1 8805.0
SDC3 8909.0
OR56B1 8913.0
OR10H4 8928.0
ACTB 8951.0
OR52L1 9013.0
TAS2R40 9098.0
OR1F1 9137.0
OR6C1 9141.0
RDH16 9148.0
OR1Q1 9162.0
TAS2R39 9198.0
OR2K2 9261.0
OR52B2 9264.0
OR4D9 9286.0
OR56A1 9303.0
OR10H5 9326.0
OR10AD1 9346.0
OR2H2 9349.0
OR8G5 9367.0
OR2AP1 9409.0
TMIE 9484.0
OR2T12 9524.0
OR4E2 9696.0
OR2M3 9816.0
KCNMB1 9859.0
OR6N1 9912.0
OR8H3 9915.0
OR6Q1 9949.0
OR2T3 9982.0
OR10A7 9986.0


REACTOME_CELL_CYCLE

REACTOME_CELL_CYCLE
190
set REACTOME_CELL_CYCLE
setSize 666
pANOVA 2.22e-08
s.dist 0.127
p.adjustANOVA 7.29e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
TUBB8 10067
POLR2J 9713
CDKN2D 9693
H2BC6 9443
PSMB3 9424
CENPH 9394
POM121 9376
SGO1 9369
CDK11A 9311
NBN 9219
NHP2 9205
RPS27A 9114
RBX1 9024
TUBB2A 9007
CDKN1C 8964
TUBB2B 8961
HAUS1 8921
HUS1 8916
H3C12 8871
TUBA8 8859

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TUBB8 10067.0
POLR2J 9713.0
CDKN2D 9693.0
H2BC6 9443.0
PSMB3 9424.0
CENPH 9394.0
POM121 9376.0
SGO1 9369.0
CDK11A 9311.0
NBN 9219.0
NHP2 9205.0
RPS27A 9114.0
RBX1 9024.0
TUBB2A 9007.0
CDKN1C 8964.0
TUBB2B 8961.0
HAUS1 8921.0
HUS1 8916.0
H3C12 8871.0
TUBA8 8859.0
TUBA4B 8804.0
H4C11 8752.0
H2BC5 8662.0
BRCA1 8635.0
PLK1 8621.0
YWHAE 8616.0
PHLDA1 8580.0
PIF1 8569.0
STAG3 8519.0
NEDD1 8453.0
CDC23 8438.0
H3C6 8421.0
TEX15 8400.0
CDC16 8398.0
PTK6 8397.0
AURKB 8361.0
PSMD12 8359.0
GMNN 8324.0
POLD4 8307.0
DYNC1LI1 8284.0
NUDC 8281.0
KPNB1 8280.0
KIF23 8240.0
PSMB2 8207.0
CENPS 8155.0
MZT2A 8145.0
ESCO2 8111.0
CHMP4C 8102.0
PSME1 8043.0
H4C1 7956.0
DMC1 7889.0
ANAPC11 7883.0
CCNH 7837.0
NUP50 7809.0
NUP98 7806.0
PRIM2 7731.0
XPO1 7719.0
MCM5 7689.0
CDCA8 7644.0
H3-3A 7620.0
HAUS8 7599.0
PSMB8 7596.0
UBE2V2 7583.0
RAE1 7570.0
RPA2 7507.0
RHNO1 7486.0
POLR2E 7472.0
HSP90AB1 7466.0
E2F5 7446.0
H2BC14 7360.0
AHCTF1 7356.0
H2BC13 7347.0
CCND3 7333.0
RAD9B 7313.0
WAPL 7310.0
SMC1B 7281.0
POLE3 7203.0
PSMB10 7164.0
TAOK1 7156.0
BUB1B 7137.0
HSPA2 7124.0
NME7 7095.0
E2F1 7078.0
MDC1 7071.0
BTRC 7063.0
CENPK 7007.0
H3C3 6984.0
REC8 6964.0
H2BC3 6957.0
UBC 6955.0
DBF4 6952.0
RFC1 6945.0
MDM2 6908.0
CDC25C 6877.0
TPX2 6848.0
POLR2C 6815.0
ORC5 6733.0
H2AC4 6694.0
MAPRE1 6689.0
FOXM1 6677.0
CCNB1 6675.0
H4C13 6661.0
SPAST 6582.0
PSMD7 6526.0
SMC4 6492.0
ITGB3BP 6440.0
DYRK1A 6439.0
ANAPC7 6436.0
CHMP3 6434.0
B9D2 6429.0
NSL1 6373.0
RBBP8 6358.0
CLASP2 6327.0
H2AZ2 6310.0
CDK6 6242.0
PSMC2 6236.0
SYCE1 6231.0
PSMB9 6207.0
CCNA2 6202.0
POLD1 6182.0
CDKN2A 6170.0
DSCC1 6116.0
WEE1 6111.0
UBB 6050.0
RAB8A 5993.0
PLK4 5974.0
SYCE3 5968.0
KAT5 5939.0
TUBB3 5910.0
CCNE2 5906.0
NUP43 5862.0
RAD17 5833.0
SYCE2 5830.0
TK1 5812.0
RAD51 5785.0
CENPT 5778.0
RCC2 5667.0
UBE2N 5648.0
TUBA4A 5624.0
CENPE 5620.0
ORC2 5616.0
NCAPD2 5607.0
POLE4 5579.0
PSMD5 5575.0
POLE2 5549.0
H3C1 5532.0
PSMD9 5509.0
CENPC 5500.0
CDK2 5496.0
PPP2R5B 5490.0
CDK4 5483.0
LIN37 5470.0
POLR2K 5445.0
H4C3 5422.0
PPP1CC 5330.0
H4C9 5309.0
MIS18BP1 5257.0
TEN1 5244.0
CDT1 5229.0
PCM1 5217.0
GTSE1 5176.0
H3-3B 5160.0
CCNB2 5156.0
CHMP7 5154.0
NCAPH 5146.0
TUBB 5134.0
MDM4 5131.0
SGO2 5049.0
CCND2 5007.0
FBXL18 4992.0
OPTN 4979.0
CSNK1E 4963.0
PSMA7 4962.0
RBL1 4892.0
BUB3 4888.0
PPP1CB 4851.0
POLR2D 4822.0
RPA1 4760.0
NUP35 4736.0
MSH4 4718.0
ZW10 4716.0
CENPN 4680.0
ZWINT 4675.0
CEP41 4630.0
CDKN2C 4628.0
KMT5A 4591.0
PSMA1 4589.0
PDS5B 4580.0
ABRAXAS1 4565.0
PPP2R2A 4552.0
ANKRD28 4534.0
DHFR 4504.0
SIRT2 4482.0
MCM3 4473.0
TUBB4A 4471.0
RAD21 4470.0
LYN 4456.0
TERF2IP 4421.0
KIF18A 4410.0
PSMC3IP 4407.0
YWHAZ 4399.0
UBE2C 4308.0
LBR 4294.0
SPO11 4287.0
FBXO5 4225.0
MND1 4205.0
PPP2CA 4197.0
CENPA 4186.0
CEP152 4176.0
PSMD4 4162.0
RAB1A 4117.0
DCTN2 4113.0
HSP90AA1 4110.0
CDCA5 4091.0
PCBP4 4051.0
H2AC14 4031.0
MIS18A 3998.0
RCC1 3988.0
H2BC12 3963.0
H3C10 3945.0
PSMD3 3937.0
MIS12 3918.0
MCPH1 3908.0
PPP6C 3880.0
AURKA 3878.0
NCAPG2 3867.0
PSME2 3849.0
MLH1 3782.0
CCNA1 3743.0
SUMO1 3699.0
UBE2D1 3621.0
BABAM1 3581.0
NUP133 3541.0
YWHAB 3519.0
CEP135 3507.0
CUL1 3500.0
CDC6 3474.0
OIP5 3452.0
RBBP4 3444.0
TMPO 3353.0
PAFAH1B1 3321.0
SFN 3304.0
HAUS6 3277.0
BORA 3257.0
NCAPG 3244.0
RAB2A 3232.0
RUVBL2 3227.0
LPIN2 3218.0
PSMC5 3212.0
TEX12 3208.0
ANAPC4 3187.0
LIN54 3120.0
BLM 3084.0
HMMR 3015.0
MASTL 2976.0
NUP85 2975.0
PSMA5 2972.0
FKBP6 2948.0
CNEP1R1 2937.0
PPP2R5A 2860.0
PSMB4 2834.0
KNL1 2830.0
TNPO1 2826.0
CEP57 2787.0
NPM1 2784.0
NUP58 2746.0
H2BC9 2696.5
H3C7 2696.5
ALMS1 2692.0
SHQ1 2657.0
PSME3 2641.0
CDK7 2611.0
NUP107 2575.0
H3C11 2569.0
CEP43 2527.0
CEP78 2466.0
GORASP2 2459.0
PRIM1 2456.0
BARD1 2399.0
UIMC1 2395.0
POLA2 2389.0
TUBB4B 2387.0
PSMA2 2366.0
RNF8 2307.0
BRCA2 2298.0
TUBG1 2291.0
NUP155 2265.0
DYNLL1 2262.0
VRK2 2183.0
CDC26 2182.0
ESCO1 2166.0
TUBG2 2122.0
TUBA3E 2102.0
EXO1 2100.0
TUBA1A 2084.0
PDS5A 2067.0
CDC14A 1998.0
NDC1 1928.0
MCM2 1927.0
CHMP2A 1810.0
MZT1 1806.0
MCM8 1757.0
NEK9 1731.0
CKS1B 1684.0
TFDP2 1681.0
CHEK1 1678.0
E2F6 1655.0
NUF2 1645.0
H2BC21 1628.0
RANBP2 1623.0
H4C4 1608.0
DSN1 1599.0
H4C16 1565.0
NDC80 1558.0
PCNA 1539.0
EML4 1493.0
RBL2 1478.0
LEMD3 1447.0
AKT2 1356.0
ANAPC5 1347.0
SET 1320.0
PIAS4 1272.0
MZT2B 1262.0
FBXW11 1250.0
PTTG1 1236.0
RFC5 1161.0
HJURP 1159.0
SDCCAG8 1129.0
MNAT1 1110.0
SFI1 1018.0
CSNK2A1 972.0
H3C4 958.0
PSMC6 933.0
POLD2 931.0
CDKN1A 915.0
STAG1 896.0
PSMA3 884.0
FEN1 855.0
H2BC17 820.0
H4C8 810.0
RAD9A 766.0
CEP250 763.0
NUP93 757.0
RFC3 686.0
IST1 616.0
SEC13 551.0
POM121C 523.0
LPIN3 511.0
NUP153 497.0
RAB1B 474.0
RAD1 470.0
UBA52 443.0
YWHAG 398.0
CHMP2B 392.0
NUP88 349.0
NUP210 310.0
LIG1 292.0
CHEK2 267.0
PSMA6 176.0
NIPBL 100.0
COP1 42.0
GSK3B 32.0
H4C6 20.0
RFC4 7.0
CEP290 -73.0
HAUS3 -111.0
RFC2 -124.0
PPP2R5D -128.0
PRKAR2B -144.0
PPP2R5C -164.0
SKA2 -206.0
KNTC1 -225.0
SPC25 -266.0
BUB1 -288.0
TYMS -416.0
TERF1 -437.0
CTC1 -460.0
CHTF18 -477.0
CEP76 -522.0
H2BC11 -531.0
WRN -532.0
CDKN1B -535.0
TP53 -582.0
SPDL1 -586.0
SPC24 -597.0
CLIP1 -605.0
ANKLE2 -623.0
ANAPC16 -645.0
DYNC1I2 -731.0
DAXX -744.0
RMI1 -777.0
NUP188 -822.0
AKAP9 -836.0
PMF1 -856.0
MAD2L1 -889.0
PSMD13 -945.0
TPR -967.0
NUP62 -1072.0
CCNE1 -1098.0
GINS2 -1104.0
SKA1 -1105.0
NDE1 -1155.0
PSMB7 -1254.0
H2BC15 -1269.0
ANAPC1 -1288.0
RAD50 -1313.0
CSNK2B -1315.0
PKMYT1 -1355.0
SMARCA5 -1377.0
TINF2 -1386.0
POLR2I -1411.0
CC2D1B -1512.0
CTDNEP1 -1517.0
RPS27 -1537.0
SRC -1560.0
LIN9 -1568.0
BRIP1 -1583.0
CHMP4A -1606.0
TUBGCP3 -1609.0
PPME1 -1614.0
CKAP5 -1621.0
UBE2I -1641.0
SEH1L -1661.0
LMNA -1752.0
PPP2R1A -1758.0
ORC4 -1798.0
POT1 -1840.0
GAR1 -1844.0
NUP214 -1861.0
PSMC1 -1911.0
MAPK1 -1913.0
TUBA1B -1967.0
LMNB1 -2007.0
CEP72 -2050.0
CEP131 -2052.0
TUBGCP5 -2058.0
BLZF1 -2062.0
NUP160 -2107.0
POLR2A -2108.0
LCMT1 -2177.0
SYCP3 -2207.0
ATM -2233.0
PSMB1 -2266.0
CENPJ -2333.0
FKBPL -2367.0
CEP63 -2398.0
UBE2E1 -2415.0
CCP110 -2418.0
TUBGCP6 -2449.0
CLASP1 -2458.0
ANAPC10 -2472.0
MCM10 -2500.0
WRAP53 -2510.0
PRDM9 -2525.0
H2BC4 -2556.0
KIF2A -2584.0
NCAPH2 -2589.0
RSF1 -2591.0
EP300 -2601.0
ACD -2629.5
MYBL2 -2635.0
H2AC20 -2685.0
FBXL7 -2717.0
ORC3 -2778.0
AAAS -2886.0
RAD51C -2903.0
LIN52 -2918.0
NEK2 -2930.0
PSMD1 -2969.0
PSMD14 -3064.0
PRKCB -3067.0
KIF20A -3085.0
NUP205 -3107.0
PSMB6 -3169.0
MCM6 -3273.0
GOLGA2 -3282.0
CENPW -3318.0
RB1 -3379.0
PSMC4 -3386.0
H3C2 -3460.0
TP53BP1 -3473.0
BABAM2 -3487.0
E2F2 -3503.0
MCM4 -3606.0
CDC27 -3640.0
VPS4A -3688.0
DIDO1 -3719.0
CENPF -3728.0
PSMB5 -3729.0
GINS4 -3731.0
CCND1 -3790.0
STN1 -3840.0
H2AC6 -3847.0
DYNC1I1 -3848.0
CDC7 -3856.0
CDK11B -3860.0
CDC20 -3888.0
HERC2 -3904.0
H2AC7 -3916.5
H2BC7 -3916.5
NUP54 -3926.0
TOP3A -4040.0
POLR2G -4059.0
SYNE2 -4066.0
SEM1 -4068.0
HAUS4 -4107.0
ENSA -4147.0
POLD3 -4151.0
E2F3 -4185.0
ODF2 -4227.0
PSME4 -4304.0
POLR2H -4306.0
ESPL1 -4329.0
RAN -4355.0
CNTRL -4420.0
NDEL1 -4470.0
MYC -4492.0
GORASP1 -4556.0
TUBB6 -4579.0
TOP2A -4651.0
CEP70 -4671.0
NSD2 -4728.0
CENPL -4733.0
ATRIP -4739.0
ARPP19 -4770.0
PPP6R3 -4777.0
NOP10 -4814.0
NUP42 -4844.0
CENPM -4846.0
PPP1R12A -4856.0
ATR -4857.0
POLR2L -4867.0
CLSPN -4931.0
H4C12 -4954.0
MSH5 -5041.0
SMC3 -5110.0
NEK7 -5120.0
PSMC3 -5134.0
DYNC1LI2 -5155.0
NINL -5183.0
CHTF8 -5187.0
PSMD2 -5230.0
PSMD6 -5301.0
BANF1 -5310.0
PSMA8 -5314.0
CHMP6 -5445.0
RPA3 -5613.0
H2BC1 -5630.0
VRK1 -5641.0
YWHAH -5666.0
POLE -5717.0
PCNT -5740.0
SYNE1 -5763.0
UBE2S -5853.0
CEP192 -5906.0
POLR2F -5909.0
FZR1 -5912.0
SUN2 -5934.0
CDC45 -5943.0
CDK1 -5988.0
H2AZ1 -5992.0
NEK6 -5993.0
DCTN1 -6015.0
HAUS2 -6028.0
RRM2 -6030.0
TFDP1 -6067.0
PRKACA -6093.0
TUBA3C -6096.0
TOPBP1 -6112.0
PPP2R5E -6139.0
H2AC18 -6150.5
H2AC19 -6150.5
CDK5RAP2 -6196.0
H2BC8 -6266.0
CENPU -6267.0
SSNA1 -6376.0
CDC25A -6410.0
MRE11 -6464.0
ACTR1A -6470.0
PSMD8 -6475.0
NUP37 -6563.0
CENPQ -6703.0
ORC6 -6767.0
TERF2 -6791.0
TUBA1C -6828.0
SYCP1 -6877.0
CEP164 -6934.0
SKP2 -6950.0
HAUS5 -6972.0
H3C8 -7012.0
AKT3 -7041.0
TUBAL3 -7065.0
TUBGCP4 -7076.0
ANAPC2 -7140.0
DNA2 -7158.0
H2AC8 -7163.0
H2AJ -7223.0
SKP1 -7268.0
ANAPC15 -7315.0
KIF2C -7340.0
LPIN1 -7372.0
MAU2 -7433.0
CENPO -7459.0
POLR2B -7479.0
MAPK3 -7509.0
JAK2 -7545.0
CDC25B -7615.0
MAD1L1 -7623.0
YWHAQ -7802.0
RNF168 -7813.0
PSMD11 -7848.0
ABL1 -7906.0
SUN1 -7945.0
USO1 -7993.0
ZNF385A -8139.0
TUBGCP2 -8171.0
ORC1 -8202.0
AKT1 -8221.0
PPP2R2D -8231.0
AJUBA -8363.0
PRKCA -8381.0
MLH3 -8403.0
H4C5 -8476.0
PPP1R12B -8507.0
CENPP -8633.0
H2BC10 -8762.0
CSNK1D -8860.0
CHMP4B -8861.0
GINS3 -8871.0
H3-4 -8982.0
CABLES1 -9087.0
CSNK2A2 -9111.0
NCAPD3 -9146.0
LEMD2 -9150.0
E2F4 -9152.0
SMC2 -9212.0
RTEL1 -9219.0
RMI2 -9269.0
PSMF1 -9271.0
NUMA1 -9337.0
MCM7 -9353.0
INCENP -9361.0
PPP2CB -9369.0
MAX -9412.0
H2AX -9465.0
HDAC1 -9524.0
ZWILCH -9723.0
GINS1 -9772.0
TUBB1 -9794.0
TERT -9905.0
PHF20 -9928.0
CDKN2B -9939.0
H4C2 -9982.0
DCTN3 -10034.0
BIRC5 -10137.0
RANGAP1 -10242.0
H2BC26 -10312.0
DYNLL2 -10341.0
SYCP2 -10352.0
PSMA4 -10354.0
DYNC1H1 -10369.0
KIF2B -10676.0
RUVBL1 -10852.0
PPP2R1B -10955.0
PSMB11 -11028.0
TUBA3D -11433.0


REACTOME_INNATE_IMMUNE_SYSTEM

REACTOME_INNATE_IMMUNE_SYSTEM
227
set REACTOME_INNATE_IMMUNE_SYSTEM
setSize 1002
pANOVA 4.14e-08
s.dist 0.102
p.adjustANOVA 1.13e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
IFNB1 10040
FOLR3 10024
IFNA7 10007
ADGRE3 9975
BST2 9971
IFNA8 9963
IFNA1 9879
SLCO4C1 9854
ILF2 9853
TRIM21 9851
TNFAIP6 9849
MCEMP1 9847
VAT1 9834
DEFA5 9785
MNDA 9776
SEMG1 9774
NCR2 9760
CCL22 9755
OLR1 9744
CD177 9741

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
IFNB1 10040.0
FOLR3 10024.0
IFNA7 10007.0
ADGRE3 9975.0
BST2 9971.0
IFNA8 9963.0
IFNA1 9879.0
SLCO4C1 9854.0
ILF2 9853.0
TRIM21 9851.0
TNFAIP6 9849.0
MCEMP1 9847.0
VAT1 9834.0
DEFA5 9785.0
MNDA 9776.0
SEMG1 9774.0
NCR2 9760.0
CCL22 9755.0
OLR1 9744.0
CD177 9741.0
CD33 9711.0
MMP9 9692.0
CFD 9688.0
DEFB125 9659.0
TREM1 9655.0
C5AR2 9624.0
C1QC 9580.0
CD68 9573.0
CR1 9560.0
IFNA2 9553.0
PRTN3 9550.0
FADD 9542.0
PRSS3 9536.0
RAB3D 9533.0
NRAS 9526.0
HSPA6 9511.0
MUC3A 9506.0
EPX 9483.0
ADGRE5 9447.0
PSMB3 9424.0
IFNA5 9289.0
GZMM 9273.0
CTSZ 9269.0
PLD4 9245.0
FGL2 9201.0
DEFB136 9136.0
IFI16 9134.0
STOM 9128.0
RPS27A 9114.0
SNAP23 9095.0
BIN2 9072.0
IRAG2 9061.0
CPNE3 9052.0
CLEC4A 9051.0
TLR10 9020.0
COMMD3 9003.0
TYROBP 8971.0
NFKBIA 8956.0
ACTB 8951.0
PYCARD 8915.0
CD93 8895.0
CFHR2 8870.0
ATF2 8853.0
ATP6V1F 8834.0
HMGB1 8830.0
CTSV 8822.0
FCER1G 8818.0
TMC6 8793.0
FPR2 8744.0
ORMDL3 8730.0
FTL 8727.0
CNPY3 8663.0
CEACAM6 8636.0
FGR 8605.0
RAC2 8599.0
GMFG 8583.0
LAT 8576.0
ATP6V1B2 8572.0
CD300E 8567.0
CLEC5A 8562.0
SIGLEC9 8560.0
FCGR2A 8543.0
LIMK1 8542.0
SIGLEC15 8514.0
EPPIN-WFDC6 8513.0
OSCAR 8512.0
FTH1 8510.0
RHOG 8505.0
RASGRP4 8495.0
NME2 8409.0
BPI 8404.0
MAP3K8 8401.0
PSMD12 8359.0
CEACAM3 8340.0
DNAJC5 8296.0
DYNC1LI1 8284.0
KPNB1 8280.0
PAFAH1B2 8267.0
NLRC4 8218.0
SFTPD 8215.0
PSMB2 8207.0
TOMM70 8204.0
PELI3 8199.0
ICAM3 8118.0
LCK 8070.0
GCA 8060.0
PSME1 8043.0
TREX1 8039.0
ATP6V1C1 8029.0
ATP6V1A 8013.0
S100A11 8007.0
ITLN1 8006.0
VNN1 7997.0
LAMTOR2 7974.0
CDA 7964.0
MUC12 7947.0
KLRD1 7937.0
ATP6V1E1 7904.0
PPBP 7884.0
SERPINB3 7880.0
GNLY 7840.0
CD19 7836.0
RAB27A 7812.0
TXNIP 7779.0
PIK3R1 7701.0
CEACAM1 7686.0
FPR1 7675.0
PLPP5 7659.0
PGM2 7643.0
TXN 7617.0
PSMB8 7596.0
EPPIN 7557.0
ECSIT 7541.0
ITGB2 7537.0
NCK1 7516.0
SELL 7514.0
POLR2E 7472.0
PPIA 7469.0
HSP90AB1 7466.0
GUSB 7448.0
COLEC10 7440.0
VTN 7424.0
MAP3K7 7394.0
ATP6V1B1 7348.0
CLU 7344.0
LCP2 7341.0
POLR3GL 7282.0
NAPRT 7263.0
IRF7 7249.0
ATOX1 7202.0
CLEC12A 7188.0
ATP6V0C 7175.0
PSMB10 7164.0
CREG1 7151.0
LILRB2 7146.0
PIN1 7112.0
TBK1 7103.0
NIT2 7066.0
BTRC 7063.0
CTSG 7027.0
CXCR1 7023.0
TIFA 6962.0
UBC 6955.0
IDH1 6953.0
POLR3H 6920.0
SOCS1 6894.0
C1orf35 6893.0
ERP44 6872.0
PGLYRP3 6861.0
B2M 6839.0
STBD1 6835.0
CASP1 6827.0
CR2 6825.0
RAB37 6789.0
IRAK2 6748.0
MUC17 6715.0
CXCR2 6702.0
HCK 6679.0
MLEC 6658.0
CASP9 6647.0
CMTM6 6642.0
PRCP 6572.0
HSPA1B 6571.0
PLAC8 6558.0
PSMD7 6526.0
CD300LB 6494.0
CD247 6493.0
BCL10 6486.0
CLEC7A 6410.0
NCKAP1L 6389.0
TLR3 6343.0
ARMC8 6341.0
SLC11A1 6330.0
DEFB129 6326.0
RAB6A 6325.0
RNF125 6307.0
TMEM179B 6293.0
CXCL1 6281.0
PIK3C3 6280.0
C1R 6269.0
GOLGA7 6261.0
ACTR10 6248.0
PSMC2 6236.0
SYK 6209.0
PSMB9 6207.0
PRDX6 6203.0
RAB4B 6201.0
TBC1D10C 6198.0
MAVS 6159.0
SLC27A2 6154.0
HLA-B 6143.0
RAB31 6140.0
UBE2D2 6124.0
LILRA3 6123.0
GM2A 6100.0
DNM1 6082.0
ARPC1B 6069.0
RNASE3 6063.0
UBB 6050.0
PLEKHO2 6045.0
CD58 5966.0
HP 5874.0
RAB3A 5872.0
MEFV 5867.0
PCBP2 5838.0
C1QA 5828.0
SERPINB1 5793.0
ALAD 5786.0
GHDC 5783.0
PLAUR 5771.0
AAMP 5768.0
GLIPR1 5735.0
SPTAN1 5720.0
C2 5679.0
ABI1 5663.0
CCT2 5661.0
TXNDC5 5658.0
MAP2K3 5651.0
UBE2N 5648.0
DUSP4 5643.0
TANK 5632.0
PAK1 5615.0
APRT 5606.0
MALT1 5591.0
PSMD5 5575.0
DEFB124 5550.0
MMP25 5543.0
RAB7A 5536.0
LAMTOR1 5521.0
PSMD9 5509.0
PRKACG 5493.0
CTSS 5489.0
GRB2 5484.0
B4GALT1 5477.0
ITCH 5460.0
HLA-A 5457.0
POLR2K 5445.0
GRN 5421.0
HSPA8 5412.0
BRI3 5385.0
ARPC5 5378.0
PRG3 5376.0
PSTPIP1 5365.0
CCR2 5337.0
NCF2 5334.0
DCD 5329.0
CFL1 5319.0
C5AR1 5315.0
PTPN11 5302.0
TMEM30A 5280.0
FCAR 5277.0
HLA-C 5275.0
MUC21 5274.0
MAPKAPK2 5270.0
IKBIP 5207.0
PRG2 5206.0
DEFB118 5190.0
P2RX7 5163.0
LYZ 5151.0
AIM2 5144.0
C8A 5142.0
ICAM2 5140.0
MAPKAPK3 5139.0
TUBB 5134.0
CTSK 5117.0
PTPRJ 5029.0
UBE2M 5026.0
RPS6KA1 5025.0
CASP8 5020.0
FCGR3B 4975.0
RAP1A 4971.0
DEFB110 4966.0
PSMA7 4962.0
CTSA 4961.0
DEFB113 4931.0
IRAK4 4917.0
POLR3D 4860.0
PGAM1 4805.0
TICAM1 4779.0
CEACAM8 4770.0
DNAJC3 4754.0
DNAJC13 4740.0
GPI 4733.0
C3AR1 4706.0
RIPK2 4691.0
GAB2 4674.0
PSMA1 4589.0
TEC 4513.0
DUSP7 4498.0
LYN 4456.0
CNN2 4418.0
TNIP2 4388.0
STK11IP 4349.0
SERPINB10 4343.0
TNFRSF1B 4297.0
WASF2 4285.0
ATP6V0A1 4259.0
PPP3R1 4210.0
NFKB1 4199.0
PPP2CA 4197.0
IL1B 4175.0
RBSN 4168.0
PSMD4 4162.0
CASP4 4149.0
GNS 4120.0
HSP90AA1 4110.0
UBE2D3 4105.0
SFTPA1 4101.0
MYD88 4093.0
MASP1 4027.0
ARPC3 4002.0
ATP6V0D2 3975.0
MME 3974.0
NKIRAS1 3968.0
MYO9B 3959.0
TLR2 3956.0
TRIM4 3944.0
PSMD3 3937.0
CCT8 3934.0
ITK 3903.0
APOB 3896.0
RASGRP2 3879.0
PTGES2 3854.0
PSME2 3849.0
NFKB2 3796.0
PTX3 3789.0
MEF2C 3788.0
C1QB 3710.0
PRKCSH 3701.0
RAB24 3675.0
XRCC6 3650.0
ATP6V1G1 3645.0
UBE2D1 3621.0
DEFB104A 3594.5
DEFB104B 3594.5
PKM 3584.0
FCER1A 3579.0
WIPF1 3539.0
CHRNB4 3528.0
MAN2B1 3518.0
DEFB115 3515.0
CUL1 3500.0
CYLD 3494.0
C1S 3492.0
AMPD3 3483.0
TLR4 3376.0
RAB18 3366.0
CD47 3342.0
NDUFC2 3333.0
SLC44A2 3286.0
CARD9 3250.0
CHUK 3247.0
COTL1 3233.0
LGMN 3229.0
ABI2 3220.0
PSMC5 3212.0
TLR5 3175.0
ADAM10 3174.0
TRAF6 3111.0
DEFB114 3106.0
PSMA5 2972.0
PDPK1 2962.0
MANBA 2941.0
TMBIM1 2876.0
DOK3 2862.0
SRP14 2853.0
HMOX1 2848.0
PSMB4 2834.0
TLR6 2822.0
ATG12 2786.0
TRAF3 2762.0
COPB1 2761.0
PROS1 2706.0
VAV1 2695.0
AGPAT2 2686.0
CRISPLD2 2672.0
MIF 2661.0
GSDMD 2652.0
PNP 2651.0
PSME3 2641.0
CRISP3 2601.0
CASP10 2564.0
CLEC4E 2545.0
DSG1 2496.0
KLRK1 2444.0
LAT2 2440.0
CCL17 2411.0
CD14 2408.0
TUBB4B 2387.0
PSMA2 2366.0
SDCBP 2361.0
RIPK3 2334.0
UBE2K 2283.0
TLR1 2278.0
DYNLL1 2262.0
LPO 2218.0
POLR1C 2186.0
NF2 2136.0
ACTR2 2095.0
CPB2 2087.0
NLRC3 2076.0
CD55 2072.0
BCL2 2010.0
USP14 1980.0
FCN2 1974.0
PELI2 1887.0
CD63 1883.0
LRRFIP1 1868.0
TRAPPC1 1812.0
SARM1 1761.0
RELB 1722.0
CTSH 1711.0
PSEN1 1710.0
HLA-E 1709.0
HVCN1 1683.0
ALDOA 1669.0
PGLYRP1 1642.0
CSTB 1633.0
DHX58 1631.0
DSN1 1599.0
PRKCD 1540.0
POLR1D 1511.0
AGL 1501.0
BPIFA1 1490.0
TICAM2 1481.0
ARSA 1470.0
DIAPH1 1451.0
SHC1 1418.0
C8G 1408.0
HERC5 1394.0
NLRC5 1342.0
RAB10 1318.0
LAIR1 1292.0
TIRAP 1286.0
FBXW11 1250.0
KRAS 1227.0
CYSTM1 1216.0
MAPK7 1191.0
CAP1 1183.0
CD53 1179.0
GLB1 1156.0
ARPC4 1134.0
RPS6KA5 1093.0
SERPING1 1091.0
AHCYL1 1088.0
DEFB116 1083.0
PIK3CA 1054.0
RAC1 1036.0
C7 1029.0
VAPA 1021.0
ARPC2 1000.0
NFAM1 991.0
STK10 981.0
PSMC6 933.0
PSMA3 884.0
ALOX5 874.0
PAK2 871.0
PLD1 861.0
CLEC10A 859.0
MS4A3 854.0
TNFAIP3 850.0
HPSE 838.0
GDI2 795.0
P2RX1 771.0
AP1M1 724.0
BIRC2 712.0
LY96 705.0
MAPK10 682.0
TXK 680.0
NOS3 650.0
CREB1 643.0
RHOF 626.0
IST1 616.0
ELANE 589.0
DYNLT1 570.0
BST1 568.0
GRAP2 542.0
NCSTN 536.0
NPC2 506.0
C3 489.0
TIMP2 488.0
IRF3 487.0
HSPA1A 453.0
UBA52 443.0
HGSNAT 401.0
MAPK11 394.0
HEXB 377.0
ENPP4 308.0
GSTP1 297.0
PLCG2 293.0
TAX1BP1 266.0
RAB14 254.0
SNAP29 249.0
PSMA6 176.0
MAP2K1 175.0
ALDH3B1 129.0
ACTR3 90.0
APAF1 73.0
HSP90B1 18.0
RAB5C 8.0
SURF4 -22.0
EEF1A1 -41.0
CDK13 -59.0
SIKE1 -70.0
CEP290 -73.0
DUSP3 -83.0
MAP2K4 -123.0
PPP2R5D -128.0
UBE2V1 -140.0
CHGA -148.0
TARM1 -152.0
C9 -166.0
CD3G -180.0
S100A12 -190.0
IFNA16 -210.0
PRKACB -259.0
NEU1 -276.0
JUN -329.0
BRK1 -357.0
ASAH1 -359.0
ATG5 -385.0
PIK3CB -397.0
CAPZA1 -421.0
DSP -438.0
QPCT -458.0
ARSB -468.0
ISG15 -518.0
GPR84 -520.0
SERPINA3 -529.0
IQGAP1 -540.0
PLD3 -544.0
ATG7 -578.0
TP53 -582.0
RNF216 -657.0
DEFA6 -660.0
NFATC3 -713.0
TCN1 -720.0
MYO10 -779.0
AP2A2 -802.0
ANO6 -807.0
TLR9 -862.0
PYGL -872.0
MEF2A -874.0
IFNA13 -893.0
TRPM2 -922.0
IRAK3 -931.0
SERPINB12 -941.0
PSMD13 -945.0
DDOST -959.0
USP18 -973.0
DEFB133 -975.0
ATAD3B -1013.0
RAB5B -1017.0
CRACR2A -1018.0
MAP3K1 -1024.0
RAP1B -1066.0
SERPINB6 -1074.0
SLC2A3 -1084.0
MUC5B -1090.0
CPNE1 -1099.0
CTSB -1115.0
LBP -1123.0
CD300A -1127.0
ATP6V1G2 -1160.0
BPIFB1 -1162.0
NKIRAS2 -1189.0
DBNL -1232.0
PSMB7 -1254.0
CPPED1 -1268.0
ATP11B -1306.0
ARPC1A -1310.0
CSNK2B -1315.0
MUC7 -1332.0
NFKBIB -1345.0
VAV2 -1353.0
CAB39 -1398.0
ATP6V0A2 -1403.0
TOM1 -1494.0
POLR3F -1528.0
SRC -1560.0
C4BPA -1561.0
DEFB121 -1565.0
VAMP8 -1575.0
MYH9 -1576.0
APEH -1581.0
ITGAL -1617.0
ATF1 -1648.0
GALNS -1659.0
VCL -1662.0
PTPRC -1663.0
MYO1C -1672.0
FABP5 -1703.0
DOCK1 -1704.0
RAP2B -1711.0
ATP6V1H -1741.0
PPP2R1A -1758.0
SERPINA1 -1796.0
PGM1 -1799.0
MAPK8 -1806.0
MAP2K6 -1817.0
MAP3K14 -1836.0
UNC93B1 -1854.0
MAPK12 -1863.0
CD46 -1884.0
NLRP3 -1885.0
GSDME -1907.0
PSMC1 -1911.0
MAPK1 -1913.0
ARHGAP45 -1931.0
ACTG1 -1934.0
POLR3E -1993.0
RHOA -1994.0
CAT -1996.0
ATP6V1D -2001.0
DEFB132 -2009.0
TCIRG1 -2035.0
ITGAM -2038.0
ELMO1 -2161.0
WIPF3 -2171.0
BIRC3 -2213.0
BPIFA2 -2224.0
PSMB1 -2266.0
CALM1 -2269.0
PTPN4 -2275.0
F2 -2364.0
HEBP2 -2386.0
A1BG -2435.0
ARL8A -2444.0
PA2G4 -2450.0
MUC20 -2462.0
MAPK14 -2491.0
GYG1 -2578.0
APP -2592.0
EP300 -2601.0
NLRP4 -2626.0
CRP -2659.0
FUCA2 -2700.0
LGALS3 -2703.0
CD209 -2710.0
DNM2 -2711.0
LEAP2 -2718.0
YES1 -2729.0
PLAU -2738.0
UBA3 -2765.0
SLPI -2801.0
XRCC5 -2812.0
LY86 -2822.0
LPCAT1 -2829.0
CASP2 -2871.0
PECAM1 -2873.0
CGAS -2877.0
ATP6V0A4 -2884.0
YPEL5 -2912.0
PSMD1 -2969.0
MYO5A -2983.0
TAB1 -3013.0
IQGAP2 -3054.0
PSMD14 -3064.0
FCN3 -3076.0
CTSC -3090.0
SCAMP1 -3143.0
MAP2K7 -3163.0
PSMB6 -3169.0
TMEM63A -3180.0
CD44 -3231.0
CD59 -3245.0
IMPDH1 -3268.0
PRKCQ -3299.0
CDC42 -3304.0
HTN1 -3329.0
PSMC4 -3386.0
FOS -3394.0
DHX36 -3457.0
CYBA -3462.0
WASF1 -3528.0
CFHR5 -3529.0
REG3A -3548.0
PLD2 -3549.0
TRIM25 -3605.0
SYNGR1 -3685.0
PSMB5 -3729.0
CD4 -3736.0
BCL2L1 -3748.0
MAPK13 -3758.0
MMP8 -3825.0
QSOX1 -3849.0
HRAS -3869.0
ANXA2 -3903.0
CLEC6A -3944.0
PIK3R2 -3958.0
PPP3CB -3976.0
MUC6 -3988.0
LAMTOR3 -4002.0
FYN -4031.0
PGLYRP4 -4053.0
SEM1 -4068.0
MGAM -4090.0
WIPF2 -4142.0
EEA1 -4169.0
DNM3 -4195.0
TAB2 -4232.0
GSN -4240.0
PPP3CA -4250.0
CFH -4254.0
LRG1 -4260.0
UNC13D -4302.0
PSME4 -4304.0
POLR2H -4306.0
SIGIRR -4316.0
CDC34 -4340.0
SLC15A4 -4371.0
DERA -4397.0
DEFB135 -4447.0
IFNA14 -4478.0
C4A -4483.5
C4B -4483.5
CLEC4C -4506.0
PTPRN2 -4518.0
SIGLEC14 -4531.0
CANT1 -4584.0
ARHGAP9 -4589.0
DEFB1 -4590.0
RAF1 -4601.0
PRKDC -4642.0
DEGS1 -4664.0
PTPN6 -4696.0
IFNA6 -4707.0
LILRB3 -4839.0
PLCG1 -4850.0
POLR2L -4867.0
S100A7A -4883.0
MUC1 -4902.0
NFATC2 -4920.0
CD180 -5097.0
CAMP -5099.0
STING1 -5114.0
PSMC3 -5134.0
CCR6 -5141.0
PELI1 -5146.0
NFATC1 -5147.0
CD36 -5161.0
HTN3 -5179.0
PRKCE -5220.0
PSMD2 -5230.0
ITPR1 -5255.0
PSMD6 -5301.0
PSMA8 -5314.0
UBR4 -5331.0
VRK3 -5352.0
MASP2 -5355.0
DOCK2 -5356.0
PDXK -5405.0
COMMD9 -5426.0
TOLLIP -5461.0
AGA -5482.0
CD81 -5520.0
CRK -5529.0
KCMF1 -5542.0
ACAA1 -5562.0
DDX41 -5604.0
S100A1 -5611.0
RNASE8 -5645.0
ROCK1 -5718.0
RNASE6 -5759.0
RNASET2 -5770.0
RNASE7 -5772.0
UBA7 -5794.0
CREBBP -5814.0
ITGAV -5886.0
MUC16 -5888.0
ITGAX -5891.0
POLR2F -5909.0
C6 -5920.0
ATP6V1E2 -5936.0
NFASC -5983.0
C4BPB -6034.0
POLR3B -6066.0
COLEC11 -6070.0
PRKACA -6093.0
EEF2 -6120.0
MPO -6131.0
HBB -6182.0
AZU1 -6184.0
FLG2 -6212.0
RASGRP1 -6213.0
ACTR1B -6236.0
CPN2 -6245.0
N4BP1 -6279.0
POLR3A -6337.0
CKAP4 -6368.0
AOC1 -6382.0
NOS1 -6383.0
CTNNB1 -6403.0
ITPR2 -6404.0
RPS6KA2 -6406.0
OSTF1 -6440.0
MRE11 -6464.0
PSMD8 -6475.0
IKBKB -6487.0
S100A8 -6490.0
POLR3C -6520.0
POLR3K -6542.0
RIPK1 -6575.0
CTSD -6584.0
KRT1 -6594.0
DGAT1 -6603.0
LAMP1 -6663.0
C8B -6671.0
TRAF2 -6686.0
HMOX2 -6697.0
PLA2G6 -6712.0
CAPN1 -6715.0
SNAP25 -6741.0
ATP6V0E1 -6747.0
MYH2 -6756.0
RNF135 -6780.0
SVIP -6786.0
ADAM8 -6806.0
DUSP6 -6830.0
DHX9 -6860.0
RELA -6863.0
SLC2A5 -6869.0
FUCA1 -6870.0
PTPRB -6922.0
ATP11A -6981.0
CAND1 -6994.0
S100B -7122.0
ATP8A1 -7130.0
ACLY -7159.0
NOS2 -7243.0
CPN1 -7249.0
LTA4H -7262.0
PTK2 -7266.0
SKP1 -7268.0
CFB -7272.0
FGB -7274.0
DPP7 -7298.0
FAF2 -7322.0
ATP8B4 -7404.0
WASL -7410.0
TSPAN14 -7411.0
NCKIPSD -7414.0
ARG1 -7443.0
FRK -7465.0
RIGI -7493.0
MAPK3 -7509.0
MAPK9 -7519.0
ADA2 -7556.0
STAT6 -7607.0
MGST1 -7618.0
KCNAB2 -7686.0
GGH -7692.0
GAA -7725.0
IFIH1 -7734.0
PSMD11 -7848.0
HK3 -7867.0
ABL1 -7906.0
WASF3 -7909.0
ATP6V1C2 -7927.0
AHSG -7937.0
UBE2L6 -7975.0
C6orf120 -8013.0
CHIT1 -8035.0
SFTPA2 -8128.0
CLEC4D -8188.0
VAV3 -8205.0
CHI3L1 -8239.0
DEFB123 -8272.0
SUGT1 -8285.0
ELMO2 -8291.0
SOS1 -8309.0
NCKAP1 -8332.0
PFKL -8341.0
OLFM4 -8391.0
DEFB126 -8412.0
C5 -8449.0
CYFIP2 -8552.0
PGLYRP2 -8592.0
CARD11 -8606.0
VPS35L -8612.0
ZBP1 -8676.0
MUC15 -8701.0
PLPP4 -8783.0
PPIE -8813.0
BAIAP2 -8835.0
NOD1 -8854.0
RNASE2 -8892.0
CFHR4 -8936.0
IKBKE -8990.0
ITPR3 -8994.0
TKFC -9057.0
POLR3G -9082.0
NHLRC3 -9119.0
PLA2G2A -9120.0
HRNR -9182.0
CAPZA2 -9218.0
TRIM56 -9227.0
CRCP -9261.0
PSMF1 -9271.0
PADI2 -9281.0
CST3 -9338.0
DEFB119 -9352.0
PPP2CB -9369.0
PIGR -9388.0
PIK3R4 -9410.0
PANX1 -9440.0
DEFB127 -9487.0
LRRC14 -9509.0
VCP -9523.0
ANPEP -9525.0
ATP6V1G3 -9547.0
IMPDH2 -9591.0
MVP -9611.0
CYFIP1 -9612.0
CYB5R3 -9627.0
ATP6V0D1 -9632.0
BPIFB6 -9636.0
ALPK1 -9651.0
IGF2R -9656.0
NCF4 -9660.0
PSAP -9668.0
IFNA21 -9675.0
CTSL -9733.0
BPIFB4 -9775.0
PYGB -9809.0
ABCA13 -9831.0
RETN -9841.0
DTX4 -9911.0
MUC13 -9922.0
ADGRG3 -9932.0
TRIM32 -9998.0
LRRC7 -10028.0
LCN2 -10030.0
PI3 -10054.0
NLRX1 -10083.0
JUP -10136.0
FGG -10138.0
SIRPB1 -10155.0
ATP6V0E2 -10160.0
PTAFR -10164.0
BPIFB2 -10174.0
AGER -10180.0
REG3G -10182.0
ACP3 -10208.0
ORM1 -10251.0
S100A9 -10322.0
PSMA4 -10354.0
DYNC1H1 -10369.0
PDAP1 -10461.0
ART1 -10481.0
MS4A2 -10497.0
ATP6V0B -10518.0
DEFB128 -10522.0
ALDOC -10577.0
RAB44 -10589.0
MUCL1 -10610.0
NLRP1 -10620.0
SIGLEC5 -10655.0
DEFA4 -10670.0
PKP1 -10684.0
LTF -10710.0
NOD2 -10711.0
FCGR3A -10716.0
NBEAL2 -10742.0
FCN1 -10758.0
CFI -10794.0
TTR -10853.0
S100P -10859.0
SIRPA -10931.0
PPP2R1B -10955.0
MUC4 -10962.0
CALML5 -10974.0
PSMB11 -11028.0
TREM2 -11062.0
MUC5AC -11141.0
SAA1 -11482.0
S100A7 -11531.0
DEFB134 -11582.0
MBL2 -11624.0
FGA -11739.0
ORM2 -11828.0
DSC1 -11859.0


REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM

REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM
78
set REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM
setSize 688
pANOVA 1.4e-07
s.dist 0.118
p.adjustANOVA 3.28e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
CCL4 10064
IFNB1 10040
IFNA7 10007
IL27 9996
BST2 9971
IFNA8 9963
IFNA1 9879
TRIM21 9851
CCL22 9755
CCL3 9737
CXCL10 9735
TNFSF8 9712
OSM 9697
MMP9 9692
PTPN7 9691
CCL5 9633
HAVCR2 9605
SLA2 9595
CCR1 9588
IL4 9579

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CCL4 10064.0
IFNB1 10040.0
IFNA7 10007.0
IL27 9996.0
BST2 9971.0
IFNA8 9963.0
IFNA1 9879.0
TRIM21 9851.0
CCL22 9755.0
CCL3 9737.0
CXCL10 9735.0
TNFSF8 9712.0
OSM 9697.0
MMP9 9692.0
PTPN7 9691.0
CCL5 9633.0
HAVCR2 9605.0
SLA2 9595.0
CCR1 9588.0
IL4 9579.0
IFNA2 9553.0
PRTN3 9550.0
NRAS 9526.0
IL11 9505.0
CCR5 9440.0
TNFSF13B 9431.0
PSMB3 9424.0
PPM1B 9416.0
POM121 9376.0
TNFSF18 9336.0
GBP2 9322.0
IFNA5 9289.0
POMC 9118.0
RPS27A 9114.0
IL17RE 9108.0
IRF8 9078.0
SH2B3 9070.0
NDN 9042.0
RBX1 9024.0
CTF1 8986.0
NFKBIA 8956.0
IL32 8950.0
RSAD2 8949.0
CANX 8922.0
IL21R 8890.0
SOX2 8872.0
H3C12 8871.0
ATF2 8853.0
HMGB1 8830.0
IL17RB 8760.0
LIF 8678.0
HLA-G 8671.0
IRF5 8658.0
TNFRSF13C 8644.0
KPNA5 8632.0
STX1A 8617.0
TNFRSF12A 8597.0
HLA-DQA2 8591.0
JUNB 8582.0
ADAR 8570.0
EBI3 8439.0
TRIM38 8437.0
TNFSF9 8434.0
H3C6 8421.0
MAP3K8 8401.0
TNFSF12 8366.0
PSMD12 8359.0
MT2A 8327.0
KPNB1 8280.0
PSMB2 8207.0
STAT4 8201.0
PELI3 8199.0
TNFRSF9 8174.0
SAMHD1 8165.0
CISH 8156.0
LCK 8070.0
PSME1 8043.0
CRLF1 8026.0
IL18 8023.0
IL12RB1 8021.0
CD86 7990.0
PIAS1 7982.0
PTPN18 7929.0
CXCL8 7859.0
FLT3LG 7834.0
BATF 7831.0
NUP50 7809.0
NUP98 7806.0
OASL 7768.0
TRIM45 7738.0
LTA 7703.0
PIK3R1 7701.0
FPR1 7675.0
PSMB8 7596.0
RAE1 7570.0
GSTA2 7562.0
RNF7 7550.0
ITGB2 7537.0
PPIA 7469.0
TNFSF4 7397.0
MAP3K7 7394.0
IFIT2 7374.0
HLA-DRA 7332.0
TWIST1 7307.0
IRF7 7249.0
TRIM8 7208.0
PSMB10 7164.0
PIN1 7112.0
TBK1 7103.0
IL18BP 7069.0
BTRC 7063.0
CTSG 7027.0
MX1 7003.0
FASLG 7002.0
H3C3 6984.0
TIFA 6962.0
UBC 6955.0
STAT5A 6933.0
TNFRSF4 6913.0
SOCS1 6894.0
B2M 6839.0
CASP1 6827.0
IL7 6809.0
IRAK2 6748.0
FOXO1 6731.0
KPNA7 6681.0
HCK 6679.0
TRIM5 6638.0
PSMD7 6526.0
LCP1 6513.0
HIF1A 6510.0
BRWD1 6445.0
PIK3R3 6443.0
IL10 6438.0
CXCL1 6281.0
PSMC2 6236.0
SYK 6209.0
PSMB9 6207.0
HLA-B 6143.0
IFIT3 6126.0
UBE2D2 6124.0
IFNGR1 6086.0
NANOG 6067.0
UBB 6050.0
IL21 6006.0
CEBPD 5990.0
FGF2 5987.0
GSTO1 5947.0
IL18R1 5917.0
SOD2 5896.0
IRF1 5865.0
NUP43 5862.0
MAP2K3 5651.0
UBE2N 5648.0
DUSP4 5643.0
INPP5D 5633.0
PSMD5 5575.0
PTPN12 5562.0
H3C1 5532.0
PSMD9 5509.0
GRB2 5484.0
IL17RC 5474.0
HLA-A 5457.0
HSPA8 5412.0
AIP 5411.0
HLA-DRB1 5396.0
IFNLR1 5383.0
CCR2 5337.0
EIF4E 5333.0
CFL1 5319.0
PTPN11 5302.0
PIK3CG 5283.0
HLA-C 5275.0
MAPKAPK2 5270.0
TGFB1 5261.0
IKBIP 5207.0
VIM 5195.0
MAPKAPK3 5139.0
IL1R2 5114.0
CRKL 5107.0
PTPRJ 5029.0
UBE2M 5026.0
RPS6KA1 5025.0
LTB 5022.0
CASP8 5020.0
CD70 4977.0
PSMA7 4962.0
TRIM31 4956.0
IL2RB 4942.0
ICAM1 4934.0
IRAK4 4917.0
IL6 4886.0
TXLNA 4863.0
HLA-F 4775.0
NUP35 4736.0
RIPK2 4691.0
GAB2 4674.0
IL18RAP 4668.0
CIITA 4617.0
PTPN1 4609.0
PSMA1 4589.0
TEC 4513.0
DUSP7 4498.0
LYN 4456.0
CNN2 4418.0
YWHAZ 4399.0
TNIP2 4388.0
SOD1 4334.0
TNFRSF1B 4297.0
IFI30 4293.0
IL1RAP 4208.0
NFKB1 4199.0
PPP2CA 4197.0
IL1B 4175.0
HLA-DPA1 4165.0
PSMD4 4162.0
ABL2 4161.0
HSP90AA1 4110.0
UBE2D3 4105.0
MYD88 4093.0
GH2 4076.0
HNRNPA2B1 4066.0
CNTFR 4003.0
NKIRAS1 3968.0
H3C10 3945.0
PSMD3 3937.0
IL1RN 3915.0
IL23A 3906.0
VAMP2 3873.0
PSME2 3849.0
IFI35 3829.0
IL2RA 3813.0
NFKB2 3796.0
MEF2C 3788.0
SUMO1 3699.0
MTAP 3634.0
IL31 3625.0
UBE2D1 3621.0
CCL2 3611.0
IFNAR1 3590.0
NUP133 3541.0
CUL1 3500.0
IL19 3363.0
CCL11 3325.0
IP6K2 3309.0
PIK3CD 3305.0
TCP1 3270.0
CHUK 3247.0
PSMC5 3212.0
SOCS2 3203.0
EIF4G2 3148.0
IL23R 3112.0
TRAF6 3111.0
CD40 3110.0
IL9 3088.0
EIF4E2 2998.0
NUP85 2975.0
PSMA5 2972.0
HMOX1 2848.0
PSMB4 2834.0
GBP3 2765.0
TRAF3 2762.0
NUP58 2746.0
H3C7 2696.5
VAV1 2695.0
PTPN2 2693.0
EIF2AK2 2662.0
MIF 2661.0
GSDMD 2652.0
PSME3 2641.0
TRIM2 2636.0
GHR 2579.0
NUP107 2575.0
H3C11 2569.0
ZEB1 2551.0
TNF 2537.0
IL15RA 2508.0
SOS2 2502.0
CAMK2D 2474.0
IL2 2429.0
IFIT1 2425.0
EDARADD 2391.0
PSMA2 2366.0
TRIM14 2329.0
HGF 2308.0
NUP155 2265.0
IRF4 2261.0
IL16 2205.0
LAMA5 2177.0
BCL6 2176.0
IL1R1 2129.0
PITPNA 2115.0
HNRNPDL 2090.0
MX2 2029.0
BCL2 2010.0
ARF1 2006.0
USP14 1980.0
TRIM34 1948.0
NDC1 1928.0
PELI2 1887.0
EIF4G3 1746.0
RELB 1722.0
PDCD4 1718.0
HLA-E 1709.0
OAS2 1640.0
HLA-DPB1 1625.0
RANBP2 1623.0
P4HB 1611.0
PTPN23 1579.0
HLA-DRB5 1572.0
PRKCD 1540.0
SHC1 1418.0
HERC5 1394.0
AKT2 1356.0
NLRC5 1342.0
BCL2L11 1271.0
FBXW11 1250.0
STAT3 1244.0
KRAS 1227.0
MAPK7 1191.0
SOCS5 1125.0
RPS6KA5 1093.0
PIK3CA 1054.0
OSMR 1039.0
H3C4 958.0
PSMC6 933.0
CDKN1A 915.0
HNRNPF 914.0
IL1RL1 913.0
PSMA3 884.0
ALOX5 874.0
PAK2 871.0
CSF1R 870.0
FLT3 848.0
IFNGR2 801.0
NUP93 757.0
IL20 741.0
OPRM1 738.0
TSLP 717.0
BIRC2 712.0
FCER2 690.0
MAPK10 682.0
CREB1 643.0
IL12B 609.0
TNFRSF18 559.0
SEC13 551.0
GRAP2 542.0
POM121C 523.0
SQSTM1 520.0
NUP153 497.0
IRF3 487.0
LGALS9 482.0
UBA52 443.0
IL4R 431.0
MAPK11 394.0
NUP88 349.0
HLA-DQB1 327.0
CBL 325.0
NUP210 310.0
PLCG2 293.0
KPNA4 229.0
IL12A 185.0
PSMA6 176.0
MAP2K1 175.0
ALOX15 174.0
POU2F1 166.0
SDC1 63.0
HSP90B1 18.0
DUSP3 -83.0
MAP2K4 -123.0
PPP2R5D -128.0
UBE2V1 -140.0
TNFRSF11B -149.0
S100A12 -190.0
CCL20 -195.0
STAT5B -204.0
IFNA16 -210.0
PDE12 -227.0
JUN -329.0
PIK3CB -397.0
CAPZA1 -421.0
CAMK2B -425.0
JAK1 -439.0
RHOU -511.0
ISG15 -518.0
CDKN1B -535.0
TP53 -582.0
IL12RB2 -587.0
IRF9 -608.0
RPLP0 -676.0
EIF4G1 -678.0
IL6R -684.0
KPNA2 -687.0
ABCE1 -741.0
STX4 -766.0
NUP188 -822.0
MEF2A -874.0
IFNA13 -893.0
EGR1 -898.0
TNFRSF13B -910.0
SMAD7 -929.0
IRAK3 -931.0
IFIT5 -942.0
PSMD13 -945.0
TPR -967.0
USP18 -973.0
EIF4A2 -993.0
RAP1B -1066.0
TRIM17 -1068.0
NUP62 -1072.0
LTBR -1080.0
LBP -1123.0
NKIRAS2 -1189.0
TNFRSF8 -1208.0
PSMB7 -1254.0
HSPA9 -1284.0
RAG2 -1305.0
PIM1 -1326.0
NFKBIB -1345.0
CASP3 -1454.0
MMP2 -1458.0
TRIM46 -1483.0
SRC -1560.0
IL26 -1566.0
ARIH1 -1574.0
SOCS6 -1618.0
ATF1 -1648.0
SEH1L -1661.0
STAT1 -1688.0
PPP2R1A -1758.0
MAPK8 -1806.0
MAP2K6 -1817.0
MAP3K14 -1836.0
NUP214 -1861.0
IL20RA -1887.0
PSMC1 -1911.0
MAPK1 -1913.0
TRIM3 -1918.0
IL36A -1990.0
RALA -1991.0
LMNB1 -2007.0
GBP4 -2018.0
ITGAM -2038.0
FSCN1 -2064.0
NUP160 -2107.0
LIFR -2164.0
IL36B -2199.0
BIRC3 -2213.0
HLA-H -2226.0
PSMB1 -2266.0
PTPN4 -2275.0
SOCS3 -2291.0
SH2B1 -2337.0
JAK3 -2393.0
UBE2E1 -2415.0
MCL1 -2490.0
MAPK14 -2491.0
TALDO1 -2527.0
CD27 -2538.0
APP -2592.0
S1PR1 -2633.0
YES1 -2729.0
UBA3 -2765.0
RORC -2858.0
AAAS -2886.0
PSMD1 -2969.0
PTPN13 -2973.0
IL5 -3001.0
TAB1 -3013.0
PSMD14 -3064.0
NUP205 -3107.0
TNFRSF17 -3118.0
THOC5 -3161.0
MAP2K7 -3163.0
PSMB6 -3169.0
TRIM6 -3219.0
CD44 -3231.0
SNRPA1 -3256.0
CDC42 -3304.0
TNFRSF11A -3326.0
RAPGEF1 -3340.0
IRS1 -3351.0
PSMC4 -3386.0
FOS -3394.0
IL24 -3434.0
SP100 -3442.0
H3C2 -3460.0
IL17C -3489.0
VEGFA -3556.0
TRIM25 -3605.0
IL33 -3665.0
IFNG -3683.0
CD80 -3697.0
IL13 -3700.0
IFI6 -3703.0
PSMB5 -3729.0
CD4 -3736.0
IL27RA -3739.0
BCL2L1 -3748.0
CCND1 -3790.0
HRAS -3869.0
PTK2B -3877.0
MMP3 -3882.0
PTPRZ1 -3884.0
ANXA2 -3903.0
NUP54 -3926.0
PIK3R2 -3958.0
FYN -4031.0
SEM1 -4068.0
F13A1 -4100.0
CAMK2G -4110.0
ANXA1 -4205.0
COL1A2 -4209.0
TAB2 -4232.0
PSME4 -4304.0
SIGIRR -4316.0
GATA3 -4320.0
STX3 -4338.0
TRIM26 -4388.0
IL5RA -4450.0
NEDD4 -4460.0
IFNA14 -4478.0
CUL5 -4482.0
MYC -4492.0
IL15 -4541.0
PTPN9 -4568.0
IFNAR2 -4571.0
OAS1 -4640.0
STXBP2 -4657.0
PTPN6 -4696.0
IFNA6 -4707.0
IL36RN -4729.0
GRB10 -4756.0
MAP3K3 -4794.0
NUP42 -4844.0
PLCG1 -4850.0
MUC1 -4902.0
TNFSF15 -4978.0
CXCL2 -5016.0
IL1RL2 -5092.0
IL10RB -5103.0
PSMC3 -5134.0
PELI1 -5146.0
CD36 -5161.0
PSMD2 -5230.0
KPNA3 -5232.0
PSMD6 -5301.0
TNFRSF1A -5309.0
PSMA8 -5314.0
TNFSF13 -5334.0
SLA -5336.0
VRK3 -5352.0
IRS2 -5397.0
STAT2 -5418.0
ELOB -5434.0
IL31RA -5443.0
TOLLIP -5461.0
CRK -5529.0
IRF6 -5564.0
RORA -5694.0
UBA7 -5794.0
INPPL1 -5811.0
CSK -5824.0
TRIM22 -5830.0
ITGAX -5891.0
IL34 -5911.0
IL17F -5914.0
CLCF1 -5974.0
PRLR -6019.0
HLA-DQB2 -6036.0
IFI27 -6041.0
PRKACA -6093.0
N4BP1 -6279.0
RPS6KA2 -6406.0
PSMD8 -6475.0
IKBKB -6487.0
NUP37 -6563.0
ADAM17 -6592.0
KPNA1 -6645.0
CCL19 -6664.0
TRAF2 -6686.0
SNAP25 -6741.0
DUSP6 -6830.0
EIF4A1 -6848.0
RELA -6863.0
IRF2 -6875.0
RNASEL -6938.0
CAMK2A -6942.0
H3C8 -7012.0
AKT3 -7041.0
TRIM10 -7042.0
SERPINB2 -7059.0
S100B -7122.0
NOS2 -7243.0
SKP1 -7268.0
EIF4A3 -7299.0
TRIM35 -7300.0
TNFRSF6B -7314.0
NCAM1 -7401.0
FOXO3 -7416.0
TYK2 -7457.0
TNFRSF25 -7484.0
RIGI -7493.0
MAPK3 -7509.0
MAPK9 -7519.0
JAK2 -7545.0
STAT6 -7607.0
ISG20 -7608.0
SMARCA4 -7614.0
FN1 -7731.0
OAS3 -7763.0
PTGS2 -7790.0
ELOC -7792.0
PSMD11 -7848.0
XAF1 -7872.0
HLA-DQA1 -7910.0
UBE2L6 -7975.0
CSF2RB -8000.0
CSF3R -8012.0
EDAR -8023.0
TRIM62 -8057.0
IL20RB -8099.0
ITGB1 -8104.0
IL22RA2 -8133.0
IL1F10 -8165.0
IL10RA -8193.0
AKT1 -8221.0
IL22 -8300.0
GBP6 -8301.0
SOS1 -8309.0
TRIM68 -8331.0
CNTF -8512.0
GBP7 -8526.0
IL17RA -8567.0
IL7R -8581.0
IL37 -8624.0
VCAM1 -8629.0
IL22RA1 -8657.0
IFITM3 -8720.0
PTPN5 -8750.0
PML -8810.0
NOD1 -8854.0
TNFSF11 -8932.0
PRL -9058.0
PSMF1 -9271.0
PPP2CB -9369.0
IFITM1 -9390.0
IFITM2 -9406.0
IL25 -9426.0
LRRC14 -9509.0
OPRD1 -9588.0
ALPK1 -9651.0
IFNA21 -9675.0
FLNB -9892.0
IL17A -9947.0
GBP1 -9995.0
PTPN14 -10014.0
SMAD3 -10027.0
LCN2 -10030.0
IL36G -10048.0
NLRX1 -10083.0
BIRC5 -10137.0
BLNK -10145.0
MMP1 -10157.0
PTAFR -10164.0
GBP5 -10166.0
AGER -10180.0
PSMA4 -10354.0
TNFSF14 -10425.0
CSF3 -10569.0
IFNL1 -10613.0
NOD2 -10711.0
EIF4E3 -10815.0
CSF2 -10880.0
IL6ST -10899.0
CSF1 -10909.0
IL1A -10953.0
PPP2R1B -10955.0
PSMB11 -11028.0
IL11RA -11060.0
TRIM29 -11094.0
IFNL2 -11224.0
CA1 -11249.0
RAG1 -11282.0
SAA1 -11482.0
IL3 -11651.0
CSH1 -11917.0
GH1 -11920.0


REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA

REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA
1146
set REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA
setSize 263
pANOVA 1.95e-07
s.dist 0.186
p.adjustANOVA 3.99e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
LSM8 9812
POLR2J 9713
LENG1 9515
CDC5L 9406
POM121 9376
SRSF7 9328
SDE2 9189
RBM8A 9122
METTL3 8944
NUDT21 8884
SMNDC1 8864
FAM32A 8836
SNRPA 8764
TRA2B 8698
SRSF10 8610
HNRNPU 8532
SNRPD1 8497
SYMPK 8342
SF3B2 8224
PPIH 8061

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
LSM8 9812
POLR2J 9713
LENG1 9515
CDC5L 9406
POM121 9376
SRSF7 9328
SDE2 9189
RBM8A 9122
METTL3 8944
NUDT21 8884
SMNDC1 8864
FAM32A 8836
SNRPA 8764
TRA2B 8698
SRSF10 8610
HNRNPU 8532
SNRPD1 8497
SYMPK 8342
SF3B2 8224
PPIH 8061
CLP1 8035
U2AF1L4 8031
SRSF8 7851
DDX39B 7841
NUP50 7809
NUP98 7806
SNRPF 7761
ZMAT2 7691
RAE1 7570
POLR2E 7472
FUS 7437
DNAJC8 7430
PRPF40A 7278
PPP1R8 7024
SNRPC 7012
ALYREF 6915
GTF2F1 6845
POLR2C 6815
DDX39A 6712
U2SURP 6670
THOC1 6646
SMU1 6483
PCBP1 6452
ZNF830 6413
SF3A3 6309
PABPN1 6091
CWC15 6058
SF3B6 6036
CACTIN 6032
PRCC 5988
DHX16 5960
CSTF1 5887
NUP43 5862
PCBP2 5838
NSRP1 5798
SNU13 5796
SNRNP35 5795
RNPS1 5700
SRSF1 5683
DHX38 5488
POLR2K 5445
HSPA8 5412
THOC3 5410
MAGOHB 5392
EIF4E 5333
NXF1 5306
CPSF6 5295
PPWD1 5191
RBM7 5123
BCAS2 4924
DDX46 4918
POLR2D 4822
NUP35 4736
SNRNP27 4699
LSM3 4690
SF3B5 4408
SNRPD2 4363
SRSF2 4219
USP39 4195
SRSF6 4086
HNRNPA2B1 4066
SRSF11 3999
PAPOLA 3964
PDCD7 3940
SNW1 3749
PNN 3679
PPIL3 3664
NUP133 3541
HNRNPD 3447
SRSF3 3435
ISY1 3431
PPIG 3411
CASC3 3359
RBM5 3289
MAGOH 3132
CPSF7 3055
NUP85 2975
CPSF2 2928
PPIL2 2896
SRSF4 2891
IK 2890
LSM5 2888
MTREX 2792
NUP58 2746
CPSF1 2683
RBM25 2645
NUP107 2575
HNRNPA3 2535
CWC22 2400
CPSF3 2377
HNRNPA1 2369
HNRNPC 2272
NUP155 2265
NCBP2 2256
HNRNPL 2196
LUC7L3 1987
SARNP 1954
NDC1 1928
SF3A2 1844
CCDC12 1836
ZCRB1 1778
GCFC2 1733
SF1 1702
RANBP2 1623
SNIP1 1569
SRSF12 1551
THOC6 1537
TXNL4A 1492
WBP11 1455
TCERG1 1391
PPIL4 1217
TFIP11 1198
PLRG1 1197
ACIN1 1138
SNRPD3 1055
FYTTD1 999
C9orf78 967
HNRNPF 914
NUP93 757
SLU7 730
PRPF4 713
RBM42 693
HNRNPK 657
LSM2 606
SEC13 551
BUD31 527
POM121C 523
NUP153 497
CWC27 459
NUP88 349
FIP1L1 322
NUP210 310
RBM17 143
PTBP1 86
DHX8 78
PRPF3 49
SUGP1 -185
DDX42 -238
SF3A1 -278
ZC3H11A -302
SF3B4 -380
PRPF31 -523
SNRPG -533
CDC40 -602
METTL14 -718
THOC7 -749
RBM39 -815
NUP188 -822
TPR -967
SAP18 -985
SRSF5 -998
NUP62 -1072
NCBP1 -1089
NXT1 -1113
PRPF6 -1182
DHX35 -1222
WTAP -1237
SRRT -1294
HNRNPM -1309
WDR70 -1338
POLR2I -1411
SLBP -1442
LSM4 -1511
PRKRIP1 -1570
CWF19L2 -1598
SEH1L -1661
SNRPE -1701
YBX1 -1821
GTF2F2 -1855
NUP214 -1861
UBL5 -1995
RNPC3 -2017
PCF11 -2051
NUP160 -2107
POLR2A -2108
CCAR1 -2178
LSM7 -2222
WBP4 -2263
SNRNP40 -2289
SNRNP70 -2390
SRRM1 -2414
SF3B1 -2443
EFTUD2 -2498
LSM6 -2885
AAAS -2886
CSTF2T -2890
CHERP -3016
NUP205 -3107
PHF5A -3146
THOC5 -3161
SNRPN -3175
GPATCH1 -3196
SNRPA1 -3256
SF3B3 -3258
SNRPB -3393
PRPF18 -3466
PRPF19 -3518
CHTOP -3569
BUD13 -3696
SYF2 -3767
NUP54 -3926
POLR2G -4059
WDR33 -4088
POLR2H -4306
SNRPB2 -4342
DHX15 -4368
HNRNPH1 -4495
CPSF4 -4580
SNRNP25 -4583
NUP42 -4844
POLR2L -4867
SNRNP200 -4979
AQR -5178
MFAP1 -5345
SRRM2 -5584
DDX41 -5604
RBM22 -5688
DDX5 -5832
POLR2F -5909
XAB2 -5969
YJU2 -6048
DDX23 -6086
HNRNPR -6181
NUP37 -6563
DHX9 -6860
PRPF38A -7147
SART1 -7232
EIF4A3 -7299
PPIL1 -7347
POLR2B -7479
SRSF9 -7612
U2AF2 -7673
CRNKL1 -7760
CSTF3 -7860
PRPF8 -7897
CWC25 -8074
GLE1 -8491
PPIE -8813
POLDIP3 -9089
PUF60 -9798
CTNNBL1 -10303
ZMAT5 -10511
SNRNP48 -11029


REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE

REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE
271
set REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE
setSize 105
pANOVA 3.46e-07
s.dist 0.288
p.adjustANOVA 6.3e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
SEC61G 9125
RPS27A 9114
SEC61B 8900
RPL19 8794
TRAM1 8769
RPL11 8697
RPL37A 8477
SEC11A 8277
RPLP1 8244
SRP54 8069
RPSA 7996
SRP72 7958
RPS7 7771
RPL18 7565
RPL35 7436
RPN1 7418
RPL23 7060
RPL7 6970
RPS15 6909
RPL26L1 6869

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SEC61G 9125.0
RPS27A 9114.0
SEC61B 8900.0
RPL19 8794.0
TRAM1 8769.0
RPL11 8697.0
RPL37A 8477.0
SEC11A 8277.0
RPLP1 8244.0
SRP54 8069.0
RPSA 7996.0
SRP72 7958.0
RPS7 7771.0
RPL18 7565.0
RPL35 7436.0
RPN1 7418.0
RPL23 7060.0
RPL7 6970.0
RPS15 6909.0
RPL26L1 6869.0
RPS3A 6799.0
RPS19 6793.0
RPL5 6098.0
RPL4 6052.0
RPL29 5923.0
RPS18 5767.0
RPS14 5716.0
SPCS1 5677.0
FAU 5468.0
SRP68 5351.0
RPL12 5203.0
RPS3 5150.0
RPL36 4951.0
RPL7A 4944.0
RPL27 4926.0
RPL9 4842.0
SRP9 4778.0
RPS26 4737.0
RPL17 4586.0
RPS9 4570.0
RPL15 4379.0
RPL31 4222.0
SSR1 4085.0
RPL24 4005.0
RPS8 3907.0
RPS29 3760.0
SRP14 2853.0
RPL21 2851.0
RPS2 2833.0
RPS27L 2825.0
RPS6 2795.0
RPS15A 2682.0
RPL3 2665.0
RPL18A 2635.0
RPLP2 2621.0
RPS5 2510.0
RPS28 2309.0
SRP19 2279.0
RPL35A 2159.0
RPS12 2017.0
RPS16 1909.0
RPS10 1666.0
RPL39L 1505.0
SPCS3 1421.0
RPL27A 1261.0
RPN2 867.0
SEC61A1 794.0
RPL36AL 783.5
RPL3L 780.0
RPL14 642.0
UBA52 443.0
RPL22 335.0
SSR2 209.0
SSR3 -250.0
RPS25 -336.0
SEC11C -505.0
RPLP0 -676.0
RPL6 -849.0
DDOST -959.0
RPL10A -1071.0
SRPRA -1346.0
RPS23 -1524.0
RPS27 -1537.0
RPL10L -1553.0
RPS20 -1729.0
RPS21 -1987.0
RPL13 -2515.0
RPS24 -2603.0
RPL30 -2610.0
SPCS2 -2706.0
RPL34 -2744.0
RPL8 -3092.0
RPL32 -3472.0
RPS11 -3542.0
RPL37 -3656.0
RPL23A -4330.0
RPL38 -4514.0
RPL28 -4919.0
RPL41 -5644.0
RPL22L1 -5689.0
RPL13A -6787.5
RPS13 -7476.0
RPL26 -8030.0
SEC61A2 -8925.0
SRPRB -9655.0


REACTOME_INFLUENZA_INFECTION

REACTOME_INFLUENZA_INFECTION
228
set REACTOME_INFLUENZA_INFECTION
setSize 149
pANOVA 4.21e-07
s.dist 0.24
p.adjustANOVA 6.91e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
POLR2J 9713
POM121 9376
RPS27A 9114
CANX 8922
RPL19 8794
RPL11 8697
KPNA5 8632
RPL37A 8477
KPNB1 8280
RPLP1 8244
RPSA 7996
CALR 7832
NUP50 7809
NUP98 7806
RPS7 7771
XPO1 7719
RAE1 7570
RPL18 7565
POLR2E 7472
RPL35 7436

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
POLR2J 9713.0
POM121 9376.0
RPS27A 9114.0
CANX 8922.0
RPL19 8794.0
RPL11 8697.0
KPNA5 8632.0
RPL37A 8477.0
KPNB1 8280.0
RPLP1 8244.0
RPSA 7996.0
CALR 7832.0
NUP50 7809.0
NUP98 7806.0
RPS7 7771.0
XPO1 7719.0
RAE1 7570.0
RPL18 7565.0
POLR2E 7472.0
RPL35 7436.0
RPL23 7060.0
RPL7 6970.0
RPS15 6909.0
RPL26L1 6869.0
GTF2F1 6845.0
POLR2C 6815.0
RPS3A 6799.0
RPS19 6793.0
KPNA7 6681.0
RPL5 6098.0
PABPN1 6091.0
RPL4 6052.0
RPL29 5923.0
NUP43 5862.0
RPS18 5767.0
RPS14 5716.0
FAU 5468.0
POLR2K 5445.0
TGFB1 5261.0
RPL12 5203.0
RPS3 5150.0
RPL36 4951.0
RPL7A 4944.0
RPL27 4926.0
RPL9 4842.0
POLR2D 4822.0
DNAJC3 4754.0
RPS26 4737.0
NUP35 4736.0
RPL17 4586.0
RPS9 4570.0
RPL15 4379.0
RPL31 4222.0
HSP90AA1 4110.0
RPL24 4005.0
RPS8 3907.0
RPS29 3760.0
CLTA 3740.0
NUP133 3541.0
NUP85 2975.0
RPL21 2851.0
RPS2 2833.0
RPS27L 2825.0
RPS6 2795.0
NUP58 2746.0
RPS15A 2682.0
RPL3 2665.0
EIF2AK2 2662.0
RPL18A 2635.0
RPLP2 2621.0
NUP107 2575.0
RPS5 2510.0
RPS28 2309.0
NUP155 2265.0
RPL35A 2159.0
RPS12 2017.0
NDC1 1928.0
RPS16 1909.0
RPS10 1666.0
RANBP2 1623.0
RPL39L 1505.0
RPL27A 1261.0
RPL36AL 783.5
RPL3L 780.0
NUP93 757.0
RPL14 642.0
SEC13 551.0
POM121C 523.0
NUP153 497.0
HSPA1A 453.0
UBA52 443.0
NUP88 349.0
RPL22 335.0
NUP210 310.0
KPNA4 229.0
CLTC -241.0
RPS25 -336.0
ISG15 -518.0
RPLP0 -676.0
KPNA2 -687.0
NUP188 -822.0
RPL6 -849.0
TPR -967.0
RPL10A -1071.0
NUP62 -1072.0
PARP1 -1343.0
POLR2I -1411.0
RPS23 -1524.0
RPS27 -1537.0
RPL10L -1553.0
SEH1L -1661.0
RPS20 -1729.0
GTF2F2 -1855.0
NUP214 -1861.0
RPS21 -1987.0
NUP160 -2107.0
POLR2A -2108.0
GRSF1 -2145.0
RPL13 -2515.0
RPS24 -2603.0
RPL30 -2610.0
RPL34 -2744.0
AAAS -2886.0
RPL8 -3092.0
NUP205 -3107.0
RPL32 -3472.0
RPS11 -3542.0
RPL37 -3656.0
NUP54 -3926.0
POLR2G -4059.0
POLR2H -4306.0
RPL23A -4330.0
RAN -4355.0
RPL38 -4514.0
CPSF4 -4580.0
NUP42 -4844.0
POLR2L -4867.0
RPL28 -4919.0
KPNA3 -5232.0
RPL41 -5644.0
RPL22L1 -5689.0
POLR2F -5909.0
NUP37 -6563.0
KPNA1 -6645.0
RPL13A -6787.5
RPS13 -7476.0
POLR2B -7479.0
RPL26 -8030.0
IPO5 -10635.0


REACTOME_NONSENSE_MEDIATED_DECAY_NMD

REACTOME_NONSENSE_MEDIATED_DECAY_NMD
1443
set REACTOME_NONSENSE_MEDIATED_DECAY_NMD
setSize 107
pANOVA 4.77e-07
s.dist 0.282
p.adjustANOVA 7.12e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
RBM8A 9122
RPS27A 9114
RPL19 8794
RPL11 8697
RPL37A 8477
RPLP1 8244
RPSA 7996
SMG8 7818
RPS7 7771
UPF1 7682
RPL18 7565
RPL35 7436
PABPC1 7158
RPL23 7060
RPL7 6970
RPS15 6909
RPL26L1 6869
RPS3A 6799
RPS19 6793
RPL5 6098

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RBM8A 9122.0
RPS27A 9114.0
RPL19 8794.0
RPL11 8697.0
RPL37A 8477.0
RPLP1 8244.0
RPSA 7996.0
SMG8 7818.0
RPS7 7771.0
UPF1 7682.0
RPL18 7565.0
RPL35 7436.0
PABPC1 7158.0
RPL23 7060.0
RPL7 6970.0
RPS15 6909.0
RPL26L1 6869.0
RPS3A 6799.0
RPS19 6793.0
RPL5 6098.0
RPL4 6052.0
RPL29 5923.0
RPS18 5767.0
RPS14 5716.0
RNPS1 5700.0
FAU 5468.0
MAGOHB 5392.0
RPL12 5203.0
RPS3 5150.0
RPL36 4951.0
RPL7A 4944.0
RPL27 4926.0
UPF3A 4844.0
RPL9 4842.0
RPS26 4737.0
RPL17 4586.0
RPS9 4570.0
PPP2R2A 4552.0
SMG5 4521.0
GSPT1 4461.0
RPL15 4379.0
SMG7 4371.0
RPL31 4222.0
PPP2CA 4197.0
RPL24 4005.0
RPS8 3907.0
RPS29 3760.0
CASC3 3359.0
MAGOH 3132.0
RPL21 2851.0
RPS2 2833.0
RPS27L 2825.0
RPS6 2795.0
RPS15A 2682.0
RPL3 2665.0
RPL18A 2635.0
RPLP2 2621.0
RPS5 2510.0
RPS28 2309.0
NCBP2 2256.0
PNRC2 2173.0
RPL35A 2159.0
RPS12 2017.0
RPS16 1909.0
RPS10 1666.0
RPL39L 1505.0
SMG9 1269.0
RPL27A 1261.0
SMG6 1104.0
RPL36AL 783.5
RPL3L 780.0
RPL14 642.0
UBA52 443.0
RPL22 335.0
UPF2 232.0
RPS25 -336.0
RPLP0 -676.0
EIF4G1 -678.0
RPL6 -849.0
RPL10A -1071.0
NCBP1 -1089.0
RPS23 -1524.0
RPS27 -1537.0
RPL10L -1553.0
RPS20 -1729.0
PPP2R1A -1758.0
DCP1A -1783.0
RPS21 -1987.0
RPL13 -2515.0
RPS24 -2603.0
RPL30 -2610.0
RPL34 -2744.0
RPL8 -3092.0
RPL32 -3472.0
RPS11 -3542.0
RPL37 -3656.0
SMG1 -4326.0
RPL23A -4330.0
RPL38 -4514.0
RPL28 -4919.0
RPL41 -5644.0
RPL22L1 -5689.0
ETF1 -6665.0
RPL13A -6787.5
EIF4A3 -7299.0
RPS13 -7476.0
RPL26 -8030.0


REACTOME_CELL_CYCLE_MITOTIC

REACTOME_CELL_CYCLE_MITOTIC
1112
set REACTOME_CELL_CYCLE_MITOTIC
setSize 539
pANOVA 5.75e-07
s.dist 0.126
p.adjustANOVA 7.87e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
TUBB8 10067
CDKN2D 9693
H2BC6 9443
PSMB3 9424
CENPH 9394
POM121 9376
SGO1 9369
CDK11A 9311
RPS27A 9114
RBX1 9024
TUBB2A 9007
CDKN1C 8964
TUBB2B 8961
HAUS1 8921
H3C12 8871
TUBA8 8859
TUBA4B 8804
H4C11 8752
H2BC5 8662
PLK1 8621

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TUBB8 10067.0
CDKN2D 9693.0
H2BC6 9443.0
PSMB3 9424.0
CENPH 9394.0
POM121 9376.0
SGO1 9369.0
CDK11A 9311.0
RPS27A 9114.0
RBX1 9024.0
TUBB2A 9007.0
CDKN1C 8964.0
TUBB2B 8961.0
HAUS1 8921.0
H3C12 8871.0
TUBA8 8859.0
TUBA4B 8804.0
H4C11 8752.0
H2BC5 8662.0
PLK1 8621.0
YWHAE 8616.0
PHLDA1 8580.0
NEDD1 8453.0
CDC23 8438.0
H3C6 8421.0
CDC16 8398.0
PTK6 8397.0
AURKB 8361.0
PSMD12 8359.0
GMNN 8324.0
POLD4 8307.0
DYNC1LI1 8284.0
NUDC 8281.0
KPNB1 8280.0
KIF23 8240.0
PSMB2 8207.0
CENPS 8155.0
MZT2A 8145.0
ESCO2 8111.0
CHMP4C 8102.0
PSME1 8043.0
H4C1 7956.0
ANAPC11 7883.0
CCNH 7837.0
NUP50 7809.0
NUP98 7806.0
PRIM2 7731.0
XPO1 7719.0
MCM5 7689.0
CDCA8 7644.0
H3-3A 7620.0
HAUS8 7599.0
PSMB8 7596.0
RAE1 7570.0
RPA2 7507.0
HSP90AB1 7466.0
E2F5 7446.0
H2BC14 7360.0
AHCTF1 7356.0
H2BC13 7347.0
CCND3 7333.0
WAPL 7310.0
POLE3 7203.0
PSMB10 7164.0
TAOK1 7156.0
BUB1B 7137.0
NME7 7095.0
E2F1 7078.0
BTRC 7063.0
CENPK 7007.0
H3C3 6984.0
H2BC3 6957.0
UBC 6955.0
DBF4 6952.0
RFC1 6945.0
CDC25C 6877.0
TPX2 6848.0
ORC5 6733.0
H2AC4 6694.0
MAPRE1 6689.0
FOXM1 6677.0
CCNB1 6675.0
H4C13 6661.0
SPAST 6582.0
PSMD7 6526.0
SMC4 6492.0
ITGB3BP 6440.0
DYRK1A 6439.0
ANAPC7 6436.0
CHMP3 6434.0
B9D2 6429.0
NSL1 6373.0
CLASP2 6327.0
H2AZ2 6310.0
CDK6 6242.0
PSMC2 6236.0
PSMB9 6207.0
CCNA2 6202.0
POLD1 6182.0
CDKN2A 6170.0
WEE1 6111.0
UBB 6050.0
RAB8A 5993.0
PLK4 5974.0
TUBB3 5910.0
CCNE2 5906.0
NUP43 5862.0
TK1 5812.0
CENPT 5778.0
RCC2 5667.0
TUBA4A 5624.0
CENPE 5620.0
ORC2 5616.0
NCAPD2 5607.0
POLE4 5579.0
PSMD5 5575.0
POLE2 5549.0
H3C1 5532.0
PSMD9 5509.0
CENPC 5500.0
CDK2 5496.0
PPP2R5B 5490.0
CDK4 5483.0
LIN37 5470.0
H4C3 5422.0
PPP1CC 5330.0
H4C9 5309.0
CDT1 5229.0
PCM1 5217.0
GTSE1 5176.0
H3-3B 5160.0
CCNB2 5156.0
CHMP7 5154.0
NCAPH 5146.0
TUBB 5134.0
SGO2 5049.0
CCND2 5007.0
FBXL18 4992.0
OPTN 4979.0
CSNK1E 4963.0
PSMA7 4962.0
RBL1 4892.0
BUB3 4888.0
PPP1CB 4851.0
RPA1 4760.0
NUP35 4736.0
ZW10 4716.0
CENPN 4680.0
ZWINT 4675.0
CEP41 4630.0
CDKN2C 4628.0
KMT5A 4591.0
PSMA1 4589.0
PDS5B 4580.0
PPP2R2A 4552.0
DHFR 4504.0
SIRT2 4482.0
MCM3 4473.0
TUBB4A 4471.0
RAD21 4470.0
LYN 4456.0
KIF18A 4410.0
UBE2C 4308.0
LBR 4294.0
FBXO5 4225.0
PPP2CA 4197.0
CENPA 4186.0
CEP152 4176.0
PSMD4 4162.0
RAB1A 4117.0
DCTN2 4113.0
HSP90AA1 4110.0
CDCA5 4091.0
H2AC14 4031.0
RCC1 3988.0
H2BC12 3963.0
H3C10 3945.0
PSMD3 3937.0
MIS12 3918.0
MCPH1 3908.0
AURKA 3878.0
NCAPG2 3867.0
PSME2 3849.0
CCNA1 3743.0
SUMO1 3699.0
UBE2D1 3621.0
NUP133 3541.0
CEP135 3507.0
CUL1 3500.0
CDC6 3474.0
RBBP4 3444.0
TMPO 3353.0
PAFAH1B1 3321.0
HAUS6 3277.0
BORA 3257.0
NCAPG 3244.0
RAB2A 3232.0
LPIN2 3218.0
PSMC5 3212.0
ANAPC4 3187.0
LIN54 3120.0
HMMR 3015.0
MASTL 2976.0
NUP85 2975.0
PSMA5 2972.0
CNEP1R1 2937.0
PPP2R5A 2860.0
PSMB4 2834.0
KNL1 2830.0
TNPO1 2826.0
CEP57 2787.0
NUP58 2746.0
H2BC9 2696.5
H3C7 2696.5
ALMS1 2692.0
PSME3 2641.0
CDK7 2611.0
NUP107 2575.0
H3C11 2569.0
CEP43 2527.0
CEP78 2466.0
GORASP2 2459.0
PRIM1 2456.0
POLA2 2389.0
TUBB4B 2387.0
PSMA2 2366.0
TUBG1 2291.0
NUP155 2265.0
DYNLL1 2262.0
VRK2 2183.0
CDC26 2182.0
ESCO1 2166.0
TUBG2 2122.0
TUBA3E 2102.0
TUBA1A 2084.0
PDS5A 2067.0
CDC14A 1998.0
NDC1 1928.0
MCM2 1927.0
CHMP2A 1810.0
MZT1 1806.0
MCM8 1757.0
NEK9 1731.0
CKS1B 1684.0
TFDP2 1681.0
E2F6 1655.0
NUF2 1645.0
H2BC21 1628.0
RANBP2 1623.0
H4C4 1608.0
DSN1 1599.0
H4C16 1565.0
NDC80 1558.0
PCNA 1539.0
EML4 1493.0
RBL2 1478.0
LEMD3 1447.0
AKT2 1356.0
ANAPC5 1347.0
SET 1320.0
MZT2B 1262.0
FBXW11 1250.0
PTTG1 1236.0
RFC5 1161.0
SDCCAG8 1129.0
MNAT1 1110.0
SFI1 1018.0
CSNK2A1 972.0
H3C4 958.0
PSMC6 933.0
POLD2 931.0
CDKN1A 915.0
STAG1 896.0
PSMA3 884.0
FEN1 855.0
H2BC17 820.0
H4C8 810.0
CEP250 763.0
NUP93 757.0
RFC3 686.0
IST1 616.0
SEC13 551.0
POM121C 523.0
LPIN3 511.0
NUP153 497.0
RAB1B 474.0
UBA52 443.0
YWHAG 398.0
CHMP2B 392.0
NUP88 349.0
NUP210 310.0
LIG1 292.0
PSMA6 176.0
NIPBL 100.0
GSK3B 32.0
H4C6 20.0
RFC4 7.0
CEP290 -73.0
HAUS3 -111.0
RFC2 -124.0
PPP2R5D -128.0
PRKAR2B -144.0
PPP2R5C -164.0
SKA2 -206.0
KNTC1 -225.0
SPC25 -266.0
BUB1 -288.0
TYMS -416.0
CEP76 -522.0
H2BC11 -531.0
CDKN1B -535.0
TP53 -582.0
SPDL1 -586.0
SPC24 -597.0
CLIP1 -605.0
ANKLE2 -623.0
ANAPC16 -645.0
DYNC1I2 -731.0
NUP188 -822.0
AKAP9 -836.0
PMF1 -856.0
MAD2L1 -889.0
PSMD13 -945.0
TPR -967.0
NUP62 -1072.0
CCNE1 -1098.0
GINS2 -1104.0
SKA1 -1105.0
NDE1 -1155.0
PSMB7 -1254.0
H2BC15 -1269.0
ANAPC1 -1288.0
CSNK2B -1315.0
PKMYT1 -1355.0
CC2D1B -1512.0
CTDNEP1 -1517.0
RPS27 -1537.0
SRC -1560.0
LIN9 -1568.0
CHMP4A -1606.0
TUBGCP3 -1609.0
PPME1 -1614.0
CKAP5 -1621.0
UBE2I -1641.0
SEH1L -1661.0
LMNA -1752.0
PPP2R1A -1758.0
ORC4 -1798.0
NUP214 -1861.0
PSMC1 -1911.0
MAPK1 -1913.0
TUBA1B -1967.0
LMNB1 -2007.0
CEP72 -2050.0
CEP131 -2052.0
TUBGCP5 -2058.0
BLZF1 -2062.0
NUP160 -2107.0
LCMT1 -2177.0
PSMB1 -2266.0
CENPJ -2333.0
FKBPL -2367.0
CEP63 -2398.0
UBE2E1 -2415.0
CCP110 -2418.0
TUBGCP6 -2449.0
CLASP1 -2458.0
ANAPC10 -2472.0
MCM10 -2500.0
H2BC4 -2556.0
KIF2A -2584.0
NCAPH2 -2589.0
EP300 -2601.0
MYBL2 -2635.0
H2AC20 -2685.0
FBXL7 -2717.0
ORC3 -2778.0
AAAS -2886.0
LIN52 -2918.0
NEK2 -2930.0
PSMD1 -2969.0
PSMD14 -3064.0
PRKCB -3067.0
KIF20A -3085.0
NUP205 -3107.0
PSMB6 -3169.0
MCM6 -3273.0
GOLGA2 -3282.0
RB1 -3379.0
PSMC4 -3386.0
H3C2 -3460.0
E2F2 -3503.0
MCM4 -3606.0
CDC27 -3640.0
VPS4A -3688.0
CENPF -3728.0
PSMB5 -3729.0
GINS4 -3731.0
CCND1 -3790.0
H2AC6 -3847.0
DYNC1I1 -3848.0
CDC7 -3856.0
CDK11B -3860.0
CDC20 -3888.0
H2AC7 -3916.5
H2BC7 -3916.5
NUP54 -3926.0
SEM1 -4068.0
HAUS4 -4107.0
ENSA -4147.0
POLD3 -4151.0
E2F3 -4185.0
ODF2 -4227.0
PSME4 -4304.0
ESPL1 -4329.0
RAN -4355.0
CNTRL -4420.0
NDEL1 -4470.0
MYC -4492.0
GORASP1 -4556.0
TUBB6 -4579.0
TOP2A -4651.0
CEP70 -4671.0
CENPL -4733.0
ARPP19 -4770.0
NUP42 -4844.0
CENPM -4846.0
PPP1R12A -4856.0
H4C12 -4954.0
SMC3 -5110.0
NEK7 -5120.0
PSMC3 -5134.0
DYNC1LI2 -5155.0
NINL -5183.0
PSMD2 -5230.0
PSMD6 -5301.0
BANF1 -5310.0
PSMA8 -5314.0
CHMP6 -5445.0
RPA3 -5613.0
H2BC1 -5630.0
VRK1 -5641.0
POLE -5717.0
PCNT -5740.0
UBE2S -5853.0
CEP192 -5906.0
FZR1 -5912.0
CDC45 -5943.0
CDK1 -5988.0
H2AZ1 -5992.0
NEK6 -5993.0
DCTN1 -6015.0
HAUS2 -6028.0
RRM2 -6030.0
TFDP1 -6067.0
PRKACA -6093.0
TUBA3C -6096.0
PPP2R5E -6139.0
H2AC18 -6150.5
H2AC19 -6150.5
CDK5RAP2 -6196.0
H2BC8 -6266.0
CENPU -6267.0
SSNA1 -6376.0
CDC25A -6410.0
ACTR1A -6470.0
PSMD8 -6475.0
NUP37 -6563.0
CENPQ -6703.0
ORC6 -6767.0
TUBA1C -6828.0
CEP164 -6934.0
SKP2 -6950.0
HAUS5 -6972.0
H3C8 -7012.0
AKT3 -7041.0
TUBAL3 -7065.0
TUBGCP4 -7076.0
ANAPC2 -7140.0
DNA2 -7158.0
H2AC8 -7163.0
H2AJ -7223.0
SKP1 -7268.0
ANAPC15 -7315.0
KIF2C -7340.0
LPIN1 -7372.0
MAU2 -7433.0
CENPO -7459.0
MAPK3 -7509.0
JAK2 -7545.0
CDC25B -7615.0
MAD1L1 -7623.0
PSMD11 -7848.0
ABL1 -7906.0
USO1 -7993.0
TUBGCP2 -8171.0
ORC1 -8202.0
AKT1 -8221.0
PPP2R2D -8231.0
AJUBA -8363.0
PRKCA -8381.0
H4C5 -8476.0
PPP1R12B -8507.0
CENPP -8633.0
H2BC10 -8762.0
CSNK1D -8860.0
CHMP4B -8861.0
GINS3 -8871.0
H3-4 -8982.0
CABLES1 -9087.0
CSNK2A2 -9111.0
NCAPD3 -9146.0
LEMD2 -9150.0
E2F4 -9152.0
SMC2 -9212.0
PSMF1 -9271.0
NUMA1 -9337.0
MCM7 -9353.0
INCENP -9361.0
PPP2CB -9369.0
MAX -9412.0
H2AX -9465.0
HDAC1 -9524.0
ZWILCH -9723.0
GINS1 -9772.0
TUBB1 -9794.0
CDKN2B -9939.0
H4C2 -9982.0
DCTN3 -10034.0
BIRC5 -10137.0
RANGAP1 -10242.0
H2BC26 -10312.0
DYNLL2 -10341.0
PSMA4 -10354.0
DYNC1H1 -10369.0
KIF2B -10676.0
PPP2R1B -10955.0
PSMB11 -11028.0
TUBA3D -11433.0


REACTOME_CELLULAR_RESPONSES_TO_STIMULI

REACTOME_CELLULAR_RESPONSES_TO_STIMULI
1314
set REACTOME_CELLULAR_RESPONSES_TO_STIMULI
setSize 779
pANOVA 1.72e-06
s.dist 0.101
p.adjustANOVA 0.000218



Top enriched genes

Top 20 genes
GeneID Gene Rank
TUBB8 10067
RLN1 10056
IFNB1 10040
TRIM21 9851
GSTA1 9786
DDX11 9747
CDKN2D 9693
HSPA6 9511
IGFBP1 9465
H2BC6 9443
PSMB3 9424
POM121 9376
KDELR3 9337
CREB3L3 9324
ATF4 9237
NBN 9219
COX5A 9214
RPS27A 9114
ASF1A 9094
GPX7 9066

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TUBB8 10067.0
RLN1 10056.0
IFNB1 10040.0
TRIM21 9851.0
GSTA1 9786.0
DDX11 9747.0
CDKN2D 9693.0
HSPA6 9511.0
IGFBP1 9465.0
H2BC6 9443.0
PSMB3 9424.0
POM121 9376.0
KDELR3 9337.0
CREB3L3 9324.0
ATF4 9237.0
NBN 9219.0
COX5A 9214.0
RPS27A 9114.0
ASF1A 9094.0
GPX7 9066.0
RBX1 9024.0
TUBB2A 9007.0
TUBB2B 8961.0
MT1B 8940.0
EXTL1 8887.0
H3C12 8871.0
TUBA8 8859.0
ATF2 8853.0
ATP6V1F 8834.0
XBP1 8811.0
TUBA4B 8804.0
RPL19 8794.0
H4C11 8752.0
RPL11 8697.0
H2BC5 8662.0
BRCA1 8635.0
YWHAE 8616.0
TRIB3 8615.0
DNAJC2 8614.0
ATP6V1B2 8572.0
HBA1 8568.0
COX6B1 8566.0
HM13 8563.0
LIMD1 8553.0
SOD3 8506.0
RPL37A 8477.0
CDC23 8438.0
H3C6 8421.0
CDC16 8398.0
PTK6 8397.0
PSMD12 8359.0
MT2A 8327.0
DYNC1LI1 8284.0
RPLP1 8244.0
PSMB2 8207.0
NDUFA4 8146.0
GFPT1 8085.0
DCTN5 8081.0
HSPB1 8046.0
PSME1 8043.0
ATP6V1C1 8029.0
ATP6V1A 8013.0
RPSA 7996.0
TKT 7976.0
LAMTOR2 7974.0
H4C1 7956.0
ATP6V1E1 7904.0
ANAPC11 7883.0
CREB3L4 7874.0
HBA2 7861.0
CXCL8 7859.0
CALR 7832.0
ASNS 7822.0
NUP50 7809.0
NUP98 7806.0
CEBPB 7781.0
TXNIP 7779.0
RPS7 7771.0
XPO1 7719.0
KPTN 7709.0
HIGD1A 7708.0
EXOSC3 7706.0
DNAJA2 7623.0
H3-3A 7620.0
TXN 7617.0
COX19 7600.0
PSMB8 7596.0
RAE1 7570.0
RPL18 7565.0
CITED2 7543.0
RPA2 7507.0
ARNT 7467.0
HSP90AB1 7466.0
KICS2 7460.0
RPL35 7436.0
H2BC14 7360.0
ATP6V1B1 7348.0
H2BC13 7347.0
H1-3 7273.0
HDGF 7238.0
ATOX1 7202.0
ATP6V0C 7175.0
PSMB10 7164.0
AKT1S1 7160.0
IMPACT 7152.0
ADD1 7149.0
HSPA2 7124.0
COX20 7088.0
E2F1 7078.0
BTRC 7063.0
RPL23 7060.0
H3C3 6984.0
RPL7 6970.0
H2BC3 6957.0
UBC 6955.0
IDH1 6953.0
RPS15 6909.0
MDM2 6908.0
RPL26L1 6869.0
AGO1 6854.0
RPS3A 6799.0
RPS19 6793.0
PRDX1 6756.0
LAMTOR5 6743.0
H2AC4 6694.0
H4C13 6661.0
HSPA1B 6571.0
PSMD7 6526.0
HIF1A 6510.0
EGLN2 6476.0
FKBP4 6470.0
STAP2 6461.0
ANAPC7 6436.0
MT1H 6368.0
SESN2 6366.0
DNAJC7 6354.0
H2AZ2 6310.0
ACTR10 6248.0
CDK6 6242.0
PSMC2 6236.0
PSMB9 6207.0
PRDX6 6203.0
CCNA2 6202.0
CDKN2A 6170.0
UBE2D2 6124.0
RPL5 6098.0
COX14 6064.0
RPL4 6052.0
UBB 6050.0
DNAJB11 6033.0
KAT5 5939.0
EZH2 5934.0
RPL29 5923.0
PPARA 5911.0
TUBB3 5910.0
CCNE2 5906.0
SOD2 5896.0
MYDGF 5879.0
HSPA4 5868.0
NUP43 5862.0
EXOSC1 5839.0
MUL1 5805.0
HMGA2 5792.0
RPS18 5767.0
BAG5 5726.0
RPS14 5716.0
MAP2K3 5651.0
TUBA4A 5624.0
HERPUD1 5590.0
PSMD5 5575.0
H3C1 5532.0
LAMTOR1 5521.0
PSMD9 5509.0
CDK2 5496.0
PPP2R5B 5490.0
CDK4 5483.0
FAU 5468.0
BMI1 5453.0
EXTL2 5432.0
H4C3 5422.0
HSPA8 5412.0
STIP1 5380.0
CREB3 5368.0
NCF2 5334.0
EXOSC5 5326.0
H4C9 5309.0
CBX8 5279.0
MAPKAPK2 5270.0
CHD9 5254.0
PPP1R15A 5228.0
RPL12 5203.0
COX7A2L 5194.0
H3-3B 5160.0
RPS3 5150.0
MAPKAPK3 5139.0
MDM4 5131.0
ACADVL 5063.0
TXNRD2 5043.0
RPS6KA1 5025.0
COX5B 4990.0
MAFG 4973.0
PSMA7 4962.0
RPL36 4951.0
RPL7A 4944.0
RPL27 4926.0
IL6 4886.0
RPL9 4842.0
RPA1 4760.0
DNAJC3 4754.0
RPS26 4737.0
NUP35 4736.0
HIF3A 4711.0
PALB2 4643.0
CDKN2C 4628.0
SEC31A 4613.0
SIN3A 4610.0
BAG2 4606.0
PSMA1 4589.0
EXOSC2 4588.0
RPL17 4586.0
RPS9 4570.0
GSTA3 4518.0
HIF1AN 4483.0
TUBB4A 4471.0
TERF2IP 4421.0
TACO1 4412.0
RPL15 4379.0
SOD1 4334.0
GPX1 4323.0
UBE2C 4308.0
HSPB2 4286.0
BLVRA 4243.0
RPL31 4222.0
NFKB1 4199.0
PSMD4 4162.0
COX18 4115.0
DCTN2 4113.0
HSP90AA1 4110.0
UBE2D3 4105.0
SSR1 4085.0
MAFK 4043.0
H2AC14 4031.0
EED 4026.0
VHL 4024.0
EXOSC4 4006.0
RPL24 4005.0
SP1 3987.0
ATP6V0D2 3975.0
H2BC12 3963.0
H3C10 3945.0
PSMD3 3937.0
RPS8 3907.0
APOB 3896.0
H1-4 3852.0
PSME2 3849.0
MEF2C 3788.0
TBL1XR1 3761.0
RPS29 3760.0
CCNA1 3743.0
NFE2L2 3741.0
ATP6V1G1 3645.0
UBE2D1 3621.0
CCL2 3611.0
NUP133 3541.0
H1-1 3520.0
CUL1 3500.0
RBBP4 3444.0
TLR4 3376.0
DNAJA1 3374.0
SMARCD3 3338.0
TXNRD1 3303.0
FNIP1 3295.0
BACH1 3266.0
ST13 3216.0
PSMC5 3212.0
ANAPC4 3187.0
EDEM1 3153.0
NOX4 3142.0
UBXN7 3129.0
MTF1 3117.0
AGO3 3026.0
NUP85 2975.0
PSMA5 2972.0
WIPI1 2951.0
KHSRP 2943.0
HSPA1L 2939.0
TNFRSF21 2877.0
RPL21 2851.0
HMOX1 2848.0
NPLOC4 2837.0
PSMB4 2834.0
RPS2 2833.0
RPS27L 2825.0
RPS6 2795.0
RNF2 2754.0
NUP58 2746.0
HDAC3 2742.0
NRIP1 2733.0
FKBP14 2727.0
NCOR1 2709.0
H2BC9 2696.5
H3C7 2696.5
RPS15A 2682.0
RPL3 2665.0
KDM6B 2659.0
MT3 2650.0
PSME3 2641.0
RPL18A 2635.0
RPLP2 2621.0
HSPA13 2603.0
NUP107 2575.0
H3C11 2569.0
CREB3L1 2555.0
DCTN6 2549.0
RPS5 2510.0
CAMK2D 2474.0
PRDX3 2458.0
SYVN1 2433.0
TUBB4B 2387.0
PSMA2 2366.0
ERN1 2341.0
RPS28 2309.0
HMGA1 2303.0
NUP155 2265.0
DYNLL1 2262.0
CDC26 2182.0
RPL35A 2159.0
TUBA3E 2102.0
TUBA1A 2084.0
RPS12 2017.0
FKBP5 1971.0
CUL2 1955.0
NDC1 1928.0
RPS16 1909.0
DCP2 1864.0
UFD1 1833.0
ATF5 1785.0
EHMT1 1700.0
TFDP2 1681.0
RPS10 1666.0
H2BC21 1628.0
RANBP2 1623.0
P4HB 1611.0
H4C4 1608.0
H4C16 1565.0
PRKCD 1540.0
RPL39L 1505.0
SHC1 1418.0
AKT2 1356.0
ANAPC5 1347.0
NR3C1 1306.0
ZBTB17 1278.0
ERO1A 1277.0
RPL27A 1261.0
HSPA5 1259.0
STAT3 1244.0
MAPK7 1191.0
ID1 1177.0
NR1D1 1115.0
FBXL17 1106.0
CSNK2A1 972.0
H3C4 958.0
SNCB 956.0
PSMC6 933.0
CDKN1A 915.0
MIOS 907.0
PSMA3 884.0
MEF2D 858.0
ETS2 847.0
H2BC17 820.0
H4C8 810.0
COX6A1 806.0
MRPL18 793.0
RPL36AL 783.5
RPL3L 780.0
NUP93 757.0
LY96 705.0
MAPK10 682.0
EIF2S1 647.0
CREB1 643.0
RPL14 642.0
SEC13 551.0
POM121C 523.0
SQSTM1 520.0
CBX2 514.0
NUP153 497.0
HSPA1A 453.0
UBA52 443.0
MAPK11 394.0
NUP88 349.0
RPL22 335.0
HIKESHI 315.0
NUP210 310.0
CHAC1 306.0
GSTP1 297.0
CASTOR1 288.0
PHC3 263.0
ERF 180.0
PSMA6 176.0
BAG4 144.0
EXOSC9 99.0
GSK3B 32.0
MIR24-2 31.0
H4C6 20.0
HSP90B1 18.0
EEF1A1 -41.0
DNAJB6 -53.0
EIF2AK1 -75.0
MAP2K4 -123.0
SCMH1 -205.0
JUN -329.0
RPS25 -336.0
CAPZA1 -421.0
CAMK2B -425.0
TERF1 -437.0
H2BC11 -531.0
CDKN1B -535.0
TP53 -582.0
DIS3 -631.0
CUL3 -638.0
ANAPC16 -645.0
HSPA12A -650.0
CEBPG -653.0
KLHDC3 -667.0
RPLP0 -676.0
CTDSP2 -721.0
DNAJB9 -727.0
DYNC1I2 -731.0
SCO1 -746.0
PHC1 -764.0
COX6C -803.0
NUP188 -822.0
TNRC6A -826.0
RPL6 -849.0
PDIA6 -916.0
GCLM -923.0
PSMD13 -945.0
HSPH1 -956.0
TPR -967.0
H1-0 -1020.0
SURF1 -1031.0
RPL10A -1071.0
NUP62 -1072.0
CCNE1 -1098.0
RAI1 -1147.0
ATP6V1G2 -1160.0
PPARGC1A -1226.0
GPX5 -1247.0
PSMB7 -1254.0
MT1M -1259.0
ITFG2 -1260.0
H2BC15 -1269.0
HSPA9 -1284.0
TNIK -1285.0
RRAGC -1286.0
ANAPC1 -1288.0
SESN1 -1296.0
RAD50 -1313.0
CSNK2B -1315.0
SIRT1 -1339.0
SRPRA -1346.0
CABIN1 -1372.0
TINF2 -1386.0
COX4I1 -1446.0
H1-5 -1447.0
MT1G -1471.0
CLOCK -1474.0
CA9 -1508.0
RPS23 -1524.0
RPS27 -1537.0
RPL10L -1553.0
H1-2 -1597.0
SEH1L -1661.0
RRAGD -1695.0
NFYA -1696.0
EIF2S2 -1726.0
RPS20 -1729.0
DDIT3 -1738.0
ATP6V1H -1741.0
LMNA -1752.0
TGS1 -1767.0
NFYB -1774.0
MAPK8 -1806.0
MAP2K6 -1817.0
NR3C2 -1824.0
POT1 -1840.0
NUP214 -1861.0
NLRP3 -1885.0
COX7C -1892.0
PSMC1 -1911.0
MAPK1 -1913.0
MAP1LC3B -1955.0
TUBA1B -1967.0
RPS21 -1987.0
CAT -1996.0
ATP6V1D -2001.0
LMNB1 -2007.0
ARFGAP1 -2029.0
TCIRG1 -2035.0
NUP160 -2107.0
EXOSC8 -2115.0
HSPA4L -2181.0
ATM -2233.0
PSMB1 -2266.0
CYCS -2296.0
LRPPRC -2315.0
ETS1 -2376.0
UBE2E1 -2415.0
ANAPC10 -2472.0
MAPK14 -2491.0
FNIP2 -2508.0
RPL13 -2515.0
TALDO1 -2527.0
AGO4 -2550.0
NQO1 -2552.0
H2BC4 -2556.0
GML -2586.0
EP300 -2601.0
RPS24 -2603.0
RPL30 -2610.0
ACD -2629.5
BAG1 -2654.0
PREB -2655.0
H2AC20 -2685.0
DEPDC5 -2693.0
GCLC -2708.0
HSPA12B -2736.0
RPL34 -2744.0
CCS -2776.0
CREBRF -2872.0
AAAS -2886.0
CRYAB -2907.0
WDR24 -2927.0
CRTC2 -2936.0
PSMD1 -2969.0
EXOSC6 -2976.0
CXXC1 -2988.0
BLVRB -3059.0
PSMD14 -3064.0
RING1 -3069.0
RPL8 -3092.0
NUP205 -3107.0
KEAP1 -3117.0
MAP2K7 -3163.0
PSMB6 -3169.0
SLC38A9 -3259.0
GSK3A -3290.0
TATDN2 -3291.0
GPX8 -3333.0
RB1 -3379.0
PSMC4 -3386.0
FOS -3394.0
TNRC6C -3416.0
H3C2 -3460.0
PRDX5 -3461.0
CYBA -3462.0
RPL32 -3472.0
E2F2 -3503.0
RPS11 -3542.0
NPRL2 -3547.0
VEGFA -3556.0
TXN2 -3572.0
CDC27 -3640.0
RPL37 -3656.0
PSMB5 -3729.0
H2AC6 -3847.0
DYNC1I1 -3848.0
H2AC7 -3916.5
H2BC7 -3916.5
NUP54 -3926.0
MT1A -3949.0
CAPZA3 -3967.0
EIF2AK3 -3971.0
LAMTOR3 -4002.0
CBX4 -4005.0
SEM1 -4068.0
CAMK2G -4110.0
E2F3 -4185.0
CBX6 -4241.0
BMT2 -4278.0
PSME4 -4304.0
NPAS2 -4309.0
RPL23A -4330.0
MAP4K4 -4344.0
MYC -4492.0
RPL38 -4514.0
HYOU1 -4538.0
MBTPS1 -4540.0
TUBB6 -4579.0
NCOA2 -4609.0
DNAJB1 -4622.0
DCTN4 -4639.0
HSPA14 -4654.0
TNRC6B -4685.0
GRB10 -4756.0
HIRA -4767.0
MAPKAPK5 -4806.0
NUP42 -4844.0
ATR -4857.0
WFS1 -4888.0
RPL28 -4919.0
H4C12 -4954.0
PGR -4959.0
DEDD2 -5030.0
USP46 -5044.0
PSMC3 -5134.0
SIN3B -5144.0
DYNC1LI2 -5155.0
DNAJA4 -5188.0
UBN1 -5199.0
PSMD2 -5230.0
PSMD6 -5301.0
PSMA8 -5314.0
BAG3 -5394.0
EIF2AK4 -5417.0
ELOB -5434.0
MLST8 -5446.0
RHEB -5497.0
ABCC1 -5515.0
CRTC3 -5517.0
PARN -5581.0
VENTX -5603.0
RPA3 -5613.0
EXOSC7 -5615.0
H2BC1 -5630.0
MED1 -5634.0
RPL41 -5644.0
RPL22L1 -5689.0
RORA -5694.0
CREBBP -5814.0
ATF3 -5834.0
YIF1A -5835.0
UBE2S -5853.0
EP400 -5884.0
HSF1 -5889.0
FZR1 -5912.0
ATP6V1E2 -5936.0
RRAGA -5987.0
H2AZ1 -5992.0
DCTN1 -6015.0
WTIP -6027.0
TFDP1 -6067.0
TUBA3C -6096.0
H2AC18 -6150.5
H2AC19 -6150.5
ME1 -6180.0
HBB -6182.0
RPS19BP1 -6242.0
CREB3L2 -6247.0
H2BC8 -6266.0
RPS6KA2 -6406.0
ATF6 -6423.0
MRE11 -6464.0
ACTR1A -6470.0
GPX6 -6473.0
PSMD8 -6475.0
SCO2 -6488.0
NFYC -6495.0
TLN1 -6498.0
COX11 -6547.0
NUP37 -6563.0
CAPZB -6607.0
HMOX2 -6697.0
IGFBP7 -6719.0
LAMTOR4 -6744.0
ATP6V0E1 -6747.0
PTGES3 -6750.0
RPL13A -6787.5
TERF2 -6791.0
TUBA1C -6828.0
RELA -6863.0
NCOR2 -6882.0
EGLN1 -6888.0
MAP3K5 -6914.0
CAMK2A -6942.0
SKP2 -6950.0
SUZ12 -6992.0
HELZ2 -7011.0
H3C8 -7012.0
AKT3 -7041.0
TUBAL3 -7065.0
ANAPC2 -7140.0
H2AC8 -7163.0
H2AJ -7223.0
SKP1 -7268.0
ANAPC15 -7315.0
RPS13 -7476.0
EPAS1 -7478.0
MAPK3 -7509.0
MAPK9 -7519.0
MT1E -7592.0
APOA1 -7619.0
CARM1 -7660.0
MOV10 -7688.0
SERP1 -7741.0
ELOC -7792.0
PSMD11 -7848.0
EGLN3 -7873.0
ATP6V1C2 -7927.0
EHMT2 -8019.0
RPL26 -8030.0
HSPB8 -8102.0
WDR59 -8185.0
AKT1 -8221.0
AJUBA -8363.0
MT1F -8384.0
MIR24-1 -8423.0
DPP3 -8455.0
H4C5 -8476.0
PRDX2 -8598.0
DCSTAMP -8666.0
CSRP1 -8685.0
SRXN1 -8746.0
MT1X -8751.0
H2BC10 -8762.0
GOSR2 -8784.0
NOTCH1 -8791.0
GCN1 -8821.0
NCOA1 -8866.0
H3-4 -8982.0
BMAL1 -9056.0
HSBP1 -9109.0
CSNK2A2 -9111.0
RXRA -9113.0
CAPZA2 -9218.0
NUDT2 -9263.0
PSMF1 -9271.0
TPP1 -9302.0
SLC46A1 -9350.0
MTOR -9408.0
NOX5 -9430.0
H2AX -9465.0
CRTC1 -9508.0
VCP -9523.0
NPRL3 -9537.0
ATP6V1G3 -9547.0
COX8A -9589.0
ATP6V0D1 -9632.0
SRPRB -9655.0
NCF4 -9660.0
PHC2 -9673.0
FLCN -9682.0
SERPINH1 -9784.0
TUBB1 -9794.0
RPTOR -9795.0
CLEC1B -9807.0
ALB -9825.0
COX16 -9862.0
SZT2 -9874.0
GPX3 -9909.0
NCOA6 -9923.0
CDKN2B -9939.0
H4C2 -9982.0
DCTN3 -10034.0
CUL7 -10088.0
ATP6V0E2 -10160.0
CCAR2 -10229.0
EPO -10238.0
H2BC26 -10312.0
MT4 -10326.0
DYNLL2 -10341.0
PSMA4 -10354.0
DYNC1H1 -10369.0
EXTL3 -10383.0
PDIA5 -10447.0
ATP6V0B -10518.0
PGD -10558.0
AQP8 -10598.0
GSR -10612.0
MINK1 -10641.0
SH3BP4 -10806.0
GPX2 -10921.0
IL1A -10953.0
SLC7A11 -10954.0
PLA2G4B -10978.0
PSMB11 -11028.0
CRYBA4 -11314.0
TUBA3D -11433.0
FABP1 -11449.0


REACTOME_INFECTIOUS_DISEASE

REACTOME_INFECTIOUS_DISEASE
974
set REACTOME_INFECTIOUS_DISEASE
setSize 910
pANOVA 2.11e-06
s.dist 0.0927
p.adjustANOVA 0.000247



Top enriched genes

Top 20 genes
GeneID Gene Rank
TUBB8 10067.0
IFNB1 10040.0
IFNA7 10007.0
BST2 9971.0
IFNA8 9963.0
IFNA1 9879.0
GNG8 9873.0
POLR2J 9713.0
IFNA2 9553.0
TUFM 9492.0
H2BC6 9443.0
CCR5 9440.0
PSMB3 9424.0
POM121 9376.0
IFNA5 9289.0
CORO1A 9260.0
VPS18 9203.0
RPS27A 9114.0
SMN1 9067.5
SMN2 9067.5

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TUBB8 10067.0
IFNB1 10040.0
IFNA7 10007.0
BST2 9971.0
IFNA8 9963.0
IFNA1 9879.0
GNG8 9873.0
POLR2J 9713.0
IFNA2 9553.0
TUFM 9492.0
H2BC6 9443.0
CCR5 9440.0
PSMB3 9424.0
POM121 9376.0
IFNA5 9289.0
CORO1A 9260.0
VPS18 9203.0
RPS27A 9114.0
SMN1 9067.5
SMN2 9067.5
RBX1 9024.0
TUBB2A 9007.0
TUBB2B 8961.0
NFKBIA 8956.0
ACTB 8951.0
PARP8 8931.0
CANX 8922.0
PYCARD 8915.0
SDC3 8909.0
H3C12 8871.0
TUBA8 8859.0
TUBA4B 8804.0
RPL19 8794.0
PPIB 8785.0
H4C11 8752.0
ENTPD5 8702.0
RPL11 8697.0
HLA-G 8671.0
H2BC5 8662.0
CD79A 8650.0
KPNA5 8632.0
STX1A 8617.0
YWHAE 8616.0
FGR 8605.0
GTF2B 8573.0
ZDHHC5 8564.0
GEMIN6 8546.0
FCGR2A 8543.0
SNRPD1 8497.0
RPL37A 8477.0
H3C6 8421.0
NLRP12 8385.0
PSMD12 8359.0
DYNC1LI1 8284.0
KPNB1 8280.0
RPLP1 8244.0
SFTPD 8215.0
PSMB2 8207.0
TOMM70 8204.0
ITGA4 8187.0
GNG13 8123.0
MGAT4A 8114.0
CHMP4C 8102.0
LCK 8070.0
PPIH 8061.0
TRIM28 8059.0
PSME1 8043.0
IL18 8023.0
RPSA 7996.0
MVB12A 7960.0
H4C1 7956.0
MTA2 7912.0
GUCY2C 7875.0
CCNH 7837.0
CALR 7832.0
NUP50 7809.0
NUP98 7806.0
TXNIP 7779.0
RPS7 7771.0
SNRPF 7761.0
XPO1 7719.0
CBX1 7712.0
GNG5 7694.0
TXN 7617.0
PSMB8 7596.0
RAE1 7570.0
RPL18 7565.0
NMI 7549.0
NCK1 7516.0
POLR2E 7472.0
PPIA 7469.0
GEMIN2 7468.0
HSP90AB1 7466.0
RPL35 7436.0
RPN1 7418.0
MAP3K7 7394.0
GTF2H3 7363.0
H2BC14 7360.0
H2BC13 7347.0
VPS37B 7270.0
IRF7 7249.0
PSMB10 7164.0
VAMP1 7104.0
TBK1 7103.0
BTRC 7063.0
RPL23 7060.0
SRPK1 7045.0
CTSG 7027.0
PRKAR2A 7019.0
H3C3 6984.0
RPL7 6970.0
H2BC3 6957.0
UBC 6955.0
RPS15 6909.0
RPL26L1 6869.0
GTF2F1 6845.0
B2M 6839.0
CASP1 6827.0
POLR2C 6815.0
RPS3A 6799.0
RPS19 6793.0
GNB2 6766.0
IRAK2 6748.0
H2AC4 6694.0
KPNA7 6681.0
HCK 6679.0
H4C13 6661.0
TAF6 6633.0
GNG11 6590.0
PSMD7 6526.0
GTF2A2 6500.0
CD247 6493.0
PARP16 6479.0
FKBP4 6470.0
MAP2K2 6450.0
IL10 6438.0
PARP6 6437.0
CHMP3 6434.0
GNG10 6399.0
NCKAP1L 6389.0
H2AC16 6379.0
GNAI2 6372.0
PIK3C3 6280.0
GOLGA7 6261.0
PSMC2 6236.0
TAF10 6230.0
MGAT1 6226.0
SYK 6209.0
PSMB9 6207.0
MAVS 6159.0
HLA-B 6143.0
STT3A 6101.0
RPL5 6098.0
CHMP5 6097.0
PABPN1 6091.0
IFNGR1 6086.0
ARPC1B 6069.0
RPL4 6052.0
UBB 6050.0
STAM2 6044.0
GNGT2 6041.0
SAP30 6035.0
CEBPD 5990.0
NOXO1 5979.0
EZH2 5934.0
GPC2 5925.0
RPL29 5923.0
RAB5A 5916.0
TUBB3 5910.0
MEFV 5867.0
NUP43 5862.0
G3BP1 5858.0
PCBP2 5838.0
RPS18 5767.0
AGRN 5753.0
RPS14 5716.0
TAF9 5675.0
ABI1 5663.0
NELFCD 5652.0
MAP2K3 5651.0
UBE2N 5648.0
TUBA4A 5624.0
PSMD5 5575.0
RAB7A 5536.0
H3C1 5532.0
GTF2E1 5511.0
PSMD9 5509.0
PRKACG 5493.0
GRB2 5484.0
IL17RC 5474.0
FAU 5468.0
ITCH 5460.0
HLA-A 5457.0
POLR2K 5445.0
H4C3 5422.0
DPEP2 5416.0
GEMIN5 5394.0
ARPC5 5378.0
PSTPIP1 5365.0
AP2S1 5363.0
H4C9 5309.0
PTPN11 5302.0
VPS36 5292.0
HLA-C 5275.0
TGFB1 5261.0
SIGMAR1 5225.0
RPL12 5203.0
FKBP1A 5202.0
VPS37A 5168.0
P2RX7 5163.0
CHMP7 5154.0
RPS3 5150.0
TUBB 5134.0
DDX20 5122.0
STX1B 5072.0
ST3GAL2 5062.0
HBEGF 5052.0
SAP30L 4997.0
DVL2 4984.0
PSMA7 4962.0
RPL36 4951.0
RPL7A 4944.0
RPL27 4926.0
IL6 4886.0
MOGS 4878.0
RPL9 4842.0
GNB3 4838.0
G3BP2 4828.0
POLR2D 4822.0
HLA-F 4775.0
DNAJC3 4754.0
RPS26 4737.0
NUP35 4736.0
C3AR1 4706.0
RIPK2 4691.0
PARP10 4644.0
CNBP 4640.0
PSMA1 4589.0
RPL17 4586.0
RPS9 4570.0
CTNND1 4544.0
TUBB4A 4471.0
LYN 4456.0
GEMIN7 4441.0
YWHAZ 4399.0
RPL15 4379.0
SNRPD2 4363.0
TAF15 4327.0
WASF2 4285.0
RPL31 4222.0
NFKB1 4199.0
IL1B 4175.0
PSMD4 4162.0
SUPT16H 4157.0
XRCC4 4136.0
HSP90AA1 4110.0
H2AC14 4031.0
MASP1 4027.0
EED 4026.0
VHL 4024.0
RPL24 4005.0
ARPC3 4002.0
RCC1 3988.0
SP1 3987.0
VPS37D 3982.0
H2BC12 3963.0
MYO9B 3959.0
TLR2 3956.0
H3C10 3945.0
TRIM4 3944.0
PSMD3 3937.0
RPS8 3907.0
VAMP2 3873.0
PSME2 3849.0
NFKB2 3796.0
MGAT4C 3781.0
NELFA 3769.0
SV2A 3763.0
TBL1XR1 3761.0
RPS29 3760.0
NFE2L2 3741.0
CLTA 3740.0
ARID4A 3715.0
PRKCSH 3701.0
SUMO1 3699.0
STAM 3678.0
XRCC6 3650.0
IFNAR1 3590.0
NUP133 3541.0
WIPF1 3539.0
AP2B1 3536.0
CCNK 3525.0
YWHAB 3519.0
RBBP4 3444.0
UBAP1 3413.0
PPIG 3411.0
H2AC21 3390.0
ISCU 3349.0
SFN 3304.0
TXNRD1 3303.0
MVB12B 3271.0
CHUK 3247.0
ABI2 3220.0
PSMC5 3212.0
GNG7 3204.0
RCOR1 3167.0
PARP9 3138.0
ZDHHC11 3116.0
TRAF6 3111.0
CSNK1A1 3016.0
RNMT 3008.0
DUSP16 3001.0
NUP85 2975.0
PSMA5 2972.0
PDPK1 2962.0
SEC23A 2953.0
RPL21 2851.0
HMOX1 2848.0
PSMB4 2834.0
RPS2 2833.0
RPS27L 2825.0
RPS6 2795.0
NPM1 2784.0
SFPQ 2779.0
TRAF3 2762.0
NUP58 2746.0
HDAC3 2742.0
FXYD6 2717.0
NCOR1 2709.0
H2BC9 2696.5
H3C7 2696.5
VAV1 2695.0
RPS15A 2682.0
RPL3 2665.0
EIF2AK2 2662.0
ANTXR2 2658.0
GSDMD 2652.0
PSME3 2641.0
RPL18A 2635.0
SUPT4H1 2627.0
RPLP2 2621.0
CDK7 2611.0
NUP107 2575.0
CCNT2 2573.0
H3C11 2569.0
TAF12 2556.0
AP1M2 2550.0
CAV1 2544.0
GATAD2B 2518.0
RPS5 2510.0
HDAC2 2417.0
TUBB4B 2387.0
HNRNPA1 2369.0
PSMA2 2366.0
RIPK3 2334.0
ANO10 2310.0
RPS28 2309.0
HMGA1 2303.0
TLR1 2278.0
NUP155 2265.0
DYNLL1 2262.0
NCBP2 2256.0
CYSLTR2 2237.0
TAF13 2220.0
RPL35A 2159.0
GPS2 2142.0
IL1R1 2129.0
TUBA3E 2102.0
ACTR2 2095.0
TUBA1A 2084.0
SDC4 2079.0
GGT5 2048.0
RPS12 2017.0
ERCC3 2011.0
ARF1 2006.0
NDC1 1928.0
RPS16 1909.0
AP1S3 1899.0
TCEA1 1869.0
HMG20B 1862.0
TAF5 1834.0
CHMP2A 1810.0
ZCRB1 1778.0
HLA-E 1709.0
ELOA 1693.0
RPS10 1666.0
HAVCR1 1643.0
H2BC21 1628.0
RANBP2 1623.0
FXYD1 1621.0
VPS45 1620.0
H4C4 1608.0
TAF4B 1592.0
GNB1 1586.0
H4C16 1565.0
RPL39L 1505.0
PARP4 1404.0
PKLR 1395.0
AKT2 1356.0
EPS15 1351.0
KDM1A 1323.0
NR3C1 1306.0
RPL27A 1261.0
SUDS3 1224.0
ARID4B 1205.0
TAF3 1202.0
ST6GALNAC2 1187.0
PLK2 1180.0
ARPC4 1134.0
MNAT1 1110.0
AHCYL1 1088.0
SNRPD3 1055.0
PSIP1 1044.0
RAC1 1036.0
NRP1 1023.0
CD163 1007.0
ARPC2 1000.0
H3C4 958.0
PSMC6 933.0
PSMA3 884.0
PAK2 871.0
RPN2 867.0
FEN1 855.0
H2BC17 820.0
H4C8 810.0
IFNGR2 801.0
MGAT2 783.5
RPL36AL 783.5
RPL3L 780.0
H2AC15 770.0
NUP93 757.0
AP1M1 724.0
CHD4 671.0
HNRNPK 657.0
CREB1 643.0
RPL14 642.0
SAR1B 608.0
GTF2H1 604.0
NOXA1 580.0
SEC13 551.0
POM121C 523.0
NUP153 497.0
C3 489.0
IRF3 487.0
FZD7 462.0
ATG14 455.0
HSPA1A 453.0
UBA52 443.0
YWHAG 398.0
CHMP2B 392.0
NUP88 349.0
RPL22 335.0
CBL 325.0
NUP210 310.0
PLCG2 293.0
LIG1 292.0
KPNA4 229.0
VTA1 193.0
PSMA6 176.0
MAP2K1 175.0
NELFE 115.0
ACTR3 90.0
SDC1 63.0
TAF11 58.0
GSK3B 32.0
H4C6 20.0
DAD1 -28.0
WNT5A -31.0
EEF1A1 -41.0
PDCD6IP -43.0
MTA3 -68.0
SIKE1 -70.0
MAP2K4 -123.0
UBE2V1 -140.0
PRKAR2B -144.0
CD3G -180.0
IFNA16 -210.0
SYT2 -236.0
CLTC -241.0
PRKACB -259.0
SMAD4 -282.0
JUN -329.0
RPS25 -336.0
BRK1 -357.0
UVRAG -379.0
FXYD7 -381.0
TMPRSS2 -398.0
JAK1 -439.0
SUPT5H -457.0
SRPK2 -465.0
ISG15 -518.0
H2BC11 -531.0
SNRPG -533.0
SEC24A -568.0
CUL3 -638.0
RPLP0 -676.0
IL6R -684.0
KPNA2 -687.0
DYNC1I2 -731.0
GNGT1 -733.0
DAXX -744.0
CD28 -775.0
MYO10 -779.0
VPS25 -797.0
AP2A2 -802.0
ANO6 -807.0
NUP188 -822.0
RPL6 -849.0
BRMS1 -851.0
TLR9 -862.0
SEC24D -884.0
IFNA13 -893.0
PSMD13 -945.0
DDOST -959.0
TPR -967.0
SAP18 -985.0
VPS28 -1014.0
GJA1 -1027.0
RPL10A -1071.0
NUP62 -1072.0
NCBP1 -1089.0
RHBDF2 -1100.0
H2AC17 -1195.0
ATP1A1 -1229.0
PSMB7 -1254.0
H2BC15 -1269.0
TSG101 -1280.0
ARPC1A -1310.0
ANO8 -1312.0
PARP1 -1343.0
VAV2 -1353.0
COMT -1368.0
POLR2I -1411.0
H2AC1 -1470.0
ANTXR1 -1477.0
GNAI3 -1491.0
RPS23 -1524.0
RPS27 -1537.0
CBLL1 -1551.0
RPL10L -1553.0
SRC -1560.0
MYH9 -1576.0
PRMT1 -1587.0
RCAN3 -1588.0
CHMP4A -1606.0
GALNT1 -1632.0
UBE2I -1641.0
EDEM2 -1647.0
SEH1L -1661.0
MYO1C -1672.0
SERPINE1 -1675.0
STAT1 -1688.0
ADCY7 -1694.0
SNRPE -1701.0
DOCK1 -1704.0
ATP1B3 -1724.0
RPS20 -1729.0
ATP6V1H -1741.0
MAPK8 -1806.0
MAP2K6 -1817.0
GTF2F2 -1855.0
ADCY3 -1857.0
NUP214 -1861.0
NLRP3 -1885.0
PSMC1 -1911.0
MAPK1 -1913.0
H2AC12 -1929.0
ACTG1 -1934.0
GATAD2A -1942.0
MAP1LC3B -1955.0
LIG4 -1958.0
TUBA1B -1967.0
ST6GALNAC4 -1978.0
RPS21 -1987.0
SYT1 -2028.0
NUP160 -2107.0
POLR2A -2108.0
SV2B -2142.0
GRSF1 -2145.0
RNGTT -2153.0
ELMO1 -2161.0
GTF2H4 -2167.0
WIPF3 -2171.0
ATP1B2 -2194.0
MGAT4B -2197.0
PSMB1 -2266.0
CALM1 -2269.0
NMT2 -2271.0
RUNX1 -2356.0
JAK3 -2393.0
ZDHHC2 -2410.0
MAPK14 -2491.0
RPL13 -2515.0
H2AC13 -2516.0
VPS16 -2539.0
ST3GAL1 -2546.0
H2BC4 -2556.0
GANAB -2564.0
APP -2592.0
PALS1 -2596.0
EP300 -2601.0
RPS24 -2603.0
RPL30 -2610.0
S1PR1 -2633.0
VPS4B -2648.0
H2AC20 -2685.0
ATP1B1 -2694.0
PACS1 -2709.0
CRBN -2720.0
YES1 -2729.0
RPL34 -2744.0
TJP1 -2787.0
XRCC5 -2812.0
AAAS -2886.0
ADCY6 -2928.0
GNB5 -2946.0
PSMD1 -2969.0
MYO5A -2983.0
ZDHHC20 -2998.0
TAB1 -3013.0
ANO3 -3017.0
GPC5 -3045.0
PSMD14 -3064.0
GTF2A1 -3089.0
RPL8 -3092.0
NUP205 -3107.0
ATP1A3 -3110.0
KEAP1 -3117.0
VPS39 -3136.0
ADCY9 -3148.0
MAP2K7 -3163.0
PSMB6 -3169.0
IMPDH1 -3268.0
GSK3A -3290.0
CDC42 -3304.0
SH3GL2 -3345.0
RB1 -3379.0
PSMC4 -3386.0
SNRPB -3393.0
ADCY8 -3404.0
RANBP1 -3452.0
H3C2 -3460.0
CYBA -3462.0
RPL32 -3472.0
WASF1 -3528.0
RPS11 -3542.0
VEGFA -3556.0
CDH1 -3562.0
TRIM25 -3605.0
RPL37 -3656.0
ADCY2 -3657.0
GEMIN4 -3673.0
VPS4A -3688.0
PSMB5 -3729.0
CD4 -3736.0
PRKAR1B -3744.0
BCL2L1 -3748.0
H2AC6 -3847.0
DYNC1I1 -3848.0
GNB4 -3850.0
H2AC11 -3853.0
TBP -3880.0
H2AC7 -3916.5
H2BC7 -3916.5
NUP54 -3926.0
ANO5 -3927.0
ELL -3930.0
ADCY1 -4026.0
FYN -4031.0
SH3GL3 -4033.0
PATJ -4042.0
ANO4 -4045.0
POLR2G -4059.0
SEM1 -4068.0
NELFB -4126.0
WIPF2 -4142.0
TAF2 -4207.0
TAB2 -4232.0
PSME4 -4304.0
POLR2H -4306.0
RPL23A -4330.0
GPC1 -4354.0
RAN -4355.0
MBD3 -4372.0
NT5E -4392.0
SEC24C -4421.0
AP1B1 -4432.0
IFNA14 -4478.0
CUL5 -4482.0
RPL38 -4514.0
CXCR4 -4516.0
ROCK2 -4537.0
IFNAR2 -4571.0
SEC24B -4574.0
TUBB6 -4579.0
CPSF4 -4580.0
PRKAR1A -4586.0
AP1G1 -4624.0
VPS33B -4652.0
PTPN6 -4696.0
PARP14 -4700.0
IFNA6 -4707.0
ZDHHC3 -4761.0
P2RX4 -4790.0
GNAS -4805.0
CRB3 -4836.0
NUP42 -4844.0
PLCG1 -4850.0
POLR2L -4867.0
RPL28 -4919.0
ST6GAL1 -4946.0
H4C12 -4954.0
GTF2E2 -4968.0
ADCY4 -4984.0
ATP1A2 -5078.0
STING1 -5114.0
PSMC3 -5134.0
DYNC1LI2 -5155.0
CCNT1 -5207.0
SNF8 -5219.0
DVL3 -5223.0
FNTA -5228.0
PSMD2 -5230.0
KPNA3 -5232.0
ITPR1 -5255.0
ANO2 -5284.0
FXYD3 -5298.0
PSMD6 -5301.0
BANF1 -5310.0
PSMA8 -5314.0
TUSC3 -5343.0
MASP2 -5355.0
DOCK2 -5356.0
STAT2 -5418.0
ELOB -5434.0
CHMP6 -5445.0
CRK -5529.0
H2BC1 -5630.0
VPS37C -5643.0
RPL41 -5644.0
ZDHHC8 -5647.0
CD9 -5652.0
CHMP1A -5664.0
YWHAH -5666.0
RPL22L1 -5689.0
ROCK1 -5718.0
ENO1 -5800.0
CREBBP -5814.0
DDX5 -5832.0
POLR2F -5909.0
IL17F -5914.0
ERCC2 -6042.0
GNG4 -6091.0
PRKACA -6093.0
TUBA3C -6096.0
EEF2 -6120.0
EGFR -6149.0
H2AC18 -6150.5
H2AC19 -6150.5
CD8B -6234.0
H2BC8 -6266.0
MET -6270.0
MGAT5 -6318.0
VPS11 -6349.0
GTF2H5 -6365.0
CTNNB1 -6403.0
ITPR2 -6404.0
ADCY5 -6416.0
GNAZ -6445.0
VPS41 -6471.0
PSMD8 -6475.0
IKBKB -6487.0
NUP37 -6563.0
RIPK1 -6575.0
ADAM17 -6592.0
MAN1B1 -6609.0
KPNA1 -6645.0
TRIM27 -6698.0
SNAP25 -6741.0
PTGES3 -6750.0
MYH2 -6756.0
RNF135 -6780.0
RPL13A -6787.5
NMT1 -6789.0
TUBA1C -6828.0
RELA -6863.0
NCOR2 -6882.0
GPC6 -6909.0
GNG2 -6961.0
ELOA2 -6968.0
SUZ12 -6992.0
H3C8 -7012.0
AKT3 -7041.0
TUBAL3 -7065.0
PDCD1 -7090.0
H2AC8 -7163.0
CDK9 -7173.0
FXYD2 -7226.0
NOS2 -7243.0
PTK2 -7266.0
SKP1 -7268.0
WASL -7410.0
NCKIPSD -7414.0
TYK2 -7457.0
RPS13 -7476.0
POLR2B -7479.0
RIGI -7493.0
MAPK3 -7509.0
SDC2 -7524.0
JAK2 -7545.0
TAF1L -7562.0
GNG12 -7573.0
ST3GAL4 -7605.0
PHF21A -7664.0
IFIH1 -7734.0
GNAT3 -7789.0
ELOC -7792.0
YWHAQ -7802.0
PSMD11 -7848.0
SLC25A4 -7895.0
ABL1 -7906.0
WASF3 -7909.0
ENTPD1 -7918.0
ANO9 -7932.0
SSRP1 -7963.0
RPL26 -8030.0
AP2A1 -8058.0
BECN1 -8094.0
LARP1 -8096.0
ITGB1 -8104.0
VPS33A -8110.0
GNG3 -8119.0
CTDP1 -8164.0
VAV3 -8205.0
AKT1 -8221.0
MTA1 -8222.0
SUGT1 -8285.0
ELMO2 -8291.0
SOS1 -8309.0
NCKAP1 -8332.0
HGS -8353.0
ST6GALNAC3 -8357.0
REST -8409.0
H4C5 -8476.0
CYFIP2 -8552.0
IL17RA -8567.0
MAN2A1 -8603.0
ZBP1 -8676.0
HSPG2 -8681.0
NEDD4L -8705.0
H2BC10 -8762.0
ST3GAL3 -8787.0
PML -8810.0
BAIAP2 -8835.0
NOD1 -8854.0
CHMP4B -8861.0
FUT8 -8879.0
ANO1 -8915.0
RNF213 -8986.0
IKBKE -8990.0
ITPR3 -8994.0
FNTB -9009.0
TKFC -9057.0
ADORA2B -9157.0
FXYD4 -9211.0
GNAI1 -9228.0
APOBEC3G -9251.0
PSMF1 -9271.0
AP2M1 -9366.0
PIK3R4 -9410.0
VCP -9523.0
HDAC1 -9524.0
IMPDH2 -9591.0
ATP1A4 -9602.0
CYFIP1 -9612.0
IFNA21 -9675.0
H2AC25 -9710.0
CTSL -9733.0
DPEP1 -9741.0
TUBB1 -9794.0
AP1S1 -9854.0
IL17A -9947.0
SH3GL1 -9965.0
H4C2 -9982.0
SMAD3 -10027.0
CHD3 -10070.0
BRD4 -10095.0
BLNK -10145.0
DVL1 -10148.0
SV2C -10206.0
TAF4 -10218.0
RANGAP1 -10242.0
TAF7 -10262.0
H2BC26 -10312.0
DYNLL2 -10341.0
PSMA4 -10354.0
DYNC1H1 -10369.0
CD79B -10378.0
ANO7 -10504.0
DPEP3 -10519.0
IPO5 -10635.0
LTF -10710.0
NOD2 -10711.0
GGT1 -10713.0
FCGR3A -10716.0
FURIN -10856.0
IL1A -10953.0
PSMB11 -11028.0
TUBA3D -11433.0
MBL2 -11624.0


REACTOME_NEUTROPHIL_DEGRANULATION

REACTOME_NEUTROPHIL_DEGRANULATION
1053
set REACTOME_NEUTROPHIL_DEGRANULATION
setSize 460
pANOVA 2.72e-06
s.dist 0.128
p.adjustANOVA 0.000298



Top enriched genes

Top 20 genes
GeneID Gene Rank
FOLR3 10024
ADGRE3 9975
BST2 9971
SLCO4C1 9854
ILF2 9853
TNFAIP6 9849
MCEMP1 9847
VAT1 9834
MNDA 9776
OLR1 9744
CD177 9741
CD33 9711
MMP9 9692
CFD 9688
CD68 9573
CR1 9560
PRTN3 9550
PRSS3 9536
RAB3D 9533
NRAS 9526

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FOLR3 10024
ADGRE3 9975
BST2 9971
SLCO4C1 9854
ILF2 9853
TNFAIP6 9849
MCEMP1 9847
VAT1 9834
MNDA 9776
OLR1 9744
CD177 9741
CD33 9711
MMP9 9692
CFD 9688
CD68 9573
CR1 9560
PRTN3 9550
PRSS3 9536
RAB3D 9533
NRAS 9526
HSPA6 9511
EPX 9483
ADGRE5 9447
CTSZ 9269
FGL2 9201
STOM 9128
SNAP23 9095
BIN2 9072
IRAG2 9061
CPNE3 9052
COMMD3 9003
TYROBP 8971
PYCARD 8915
CD93 8895
HMGB1 8830
FCER1G 8818
TMC6 8793
FPR2 8744
ORMDL3 8730
FTL 8727
CEACAM6 8636
FGR 8605
GMFG 8583
CLEC5A 8562
SIGLEC9 8560
FCGR2A 8543
OSCAR 8512
FTH1 8510
RHOG 8505
NME2 8409
BPI 8404
PSMD12 8359
CEACAM3 8340
DNAJC5 8296
DYNC1LI1 8284
KPNB1 8280
PAFAH1B2 8267
GCA 8060
S100A11 8007
VNN1 7997
LAMTOR2 7974
CDA 7964
PPBP 7884
SERPINB3 7880
RAB27A 7812
CEACAM1 7686
FPR1 7675
PGM2 7643
ITGB2 7537
SELL 7514
PPIA 7469
HSP90AB1 7466
GUSB 7448
NAPRT 7263
CLEC12A 7188
ATP6V0C 7175
CREG1 7151
LILRB2 7146
NIT2 7066
CTSG 7027
CXCR1 7023
IDH1 6953
C1orf35 6893
ERP44 6872
B2M 6839
STBD1 6835
RAB37 6789
CXCR2 6702
MLEC 6658
CMTM6 6642
PRCP 6572
HSPA1B 6571
PLAC8 6558
PSMD7 6526
NCKAP1L 6389
ARMC8 6341
SLC11A1 6330
RAB6A 6325
TMEM179B 6293
CXCL1 6281
GOLGA7 6261
ACTR10 6248
PSMC2 6236
PRDX6 6203
RAB4B 6201
TBC1D10C 6198
SLC27A2 6154
HLA-B 6143
RAB31 6140
LILRA3 6123
GM2A 6100
RNASE3 6063
PLEKHO2 6045
CD58 5966
HP 5874
RAB3A 5872
SERPINB1 5793
ALAD 5786
GHDC 5783
PLAUR 5771
GLIPR1 5735
SPTAN1 5720
CCT2 5661
TXNDC5 5658
APRT 5606
MMP25 5543
RAB7A 5536
LAMTOR1 5521
CTSS 5489
B4GALT1 5477
HLA-A 5457
GRN 5421
HSPA8 5412
BRI3 5385
ARPC5 5378
PRG3 5376
C5AR1 5315
TMEM30A 5280
FCAR 5277
HLA-C 5275
PRG2 5206
LYZ 5151
TUBB 5134
PTPRJ 5029
FCGR3B 4975
RAP1A 4971
CTSA 4961
PGAM1 4805
CEACAM8 4770
DNAJC3 4754
DNAJC13 4740
GPI 4733
C3AR1 4706
CNN2 4418
STK11IP 4349
SERPINB10 4343
TNFRSF1B 4297
ATP6V0A1 4259
NFKB1 4199
GNS 4120
HSP90AA1 4110
MME 3974
TLR2 3956
PSMD3 3937
CCT8 3934
PTGES2 3854
PTX3 3789
RAB24 3675
XRCC6 3650
PKM 3584
CHRNB4 3528
MAN2B1 3518
AMPD3 3483
RAB18 3366
CD47 3342
NDUFC2 3333
SLC44A2 3286
COTL1 3233
ADAM10 3174
PSMA5 2972
MANBA 2941
TMBIM1 2876
DOK3 2862
SRP14 2853
COPB1 2761
AGPAT2 2686
CRISPLD2 2672
MIF 2661
GSDMD 2652
PNP 2651
CRISP3 2601
DSG1 2496
CD14 2408
TUBB4B 2387
PSMA2 2366
SDCBP 2361
DYNLL1 2262
ACTR2 2095
CD55 2072
CD63 1883
TRAPPC1 1812
CTSH 1711
PSEN1 1710
HVCN1 1683
ALDOA 1669
PGLYRP1 1642
CSTB 1633
DSN1 1599
PRKCD 1540
AGL 1501
TICAM2 1481
ARSA 1470
DIAPH1 1451
RAB10 1318
LAIR1 1292
CYSTM1 1216
CAP1 1183
CD53 1179
GLB1 1156
RAC1 1036
VAPA 1021
NFAM1 991
STK10 981
ALOX5 874
PLD1 861
MS4A3 854
HPSE 838
GDI2 795
P2RX1 771
AP1M1 724
RHOF 626
IST1 616
ELANE 589
DYNLT1 570
BST1 568
NCSTN 536
NPC2 506
C3 489
TIMP2 488
HSPA1A 453
HGSNAT 401
HEXB 377
ENPP4 308
GSTP1 297
RAB14 254
SNAP29 249
ALDH3B1 129
APAF1 73
RAB5C 8
SURF4 -22
EEF1A1 -41
CDK13 -59
CEP290 -73
TARM1 -152
S100A12 -190
NEU1 -276
ASAH1 -359
DSP -438
QPCT -458
ARSB -468
GPR84 -520
SERPINA3 -529
IQGAP1 -540
ATG7 -578
TCN1 -720
AP2A2 -802
ANO6 -807
PYGL -872
TRPM2 -922
SERPINB12 -941
PSMD13 -945
DDOST -959
ATAD3B -1013
RAB5B -1017
CRACR2A -1018
RAP1B -1066
SERPINB6 -1074
SLC2A3 -1084
CPNE1 -1099
CTSB -1115
CD300A -1127
DBNL -1232
PSMB7 -1254
CPPED1 -1268
ATP11B -1306
CSNK2B -1315
CAB39 -1398
TOM1 -1494
VAMP8 -1575
APEH -1581
ITGAL -1617
GALNS -1659
VCL -1662
PTPRC -1663
FABP5 -1703
RAP2B -1711
SERPINA1 -1796
PGM1 -1799
MAPK1 -1913
ARHGAP45 -1931
RHOA -1994
CAT -1996
ATP6V1D -2001
TCIRG1 -2035
ITGAM -2038
PSMB1 -2266
HEBP2 -2386
A1BG -2435
ARL8A -2444
PA2G4 -2450
MAPK14 -2491
GYG1 -2578
FUCA2 -2700
LGALS3 -2703
PLAU -2738
SLPI -2801
XRCC5 -2812
LPCAT1 -2829
PECAM1 -2873
YPEL5 -2912
PSMD1 -2969
IQGAP2 -3054
PSMD14 -3064
CTSC -3090
SCAMP1 -3143
TMEM63A -3180
CD44 -3231
CD59 -3245
IMPDH1 -3268
CYBA -3462
SYNGR1 -3685
MMP8 -3825
QSOX1 -3849
ANXA2 -3903
LAMTOR3 -4002
MGAM -4090
GSN -4240
LRG1 -4260
UNC13D -4302
SLC15A4 -4371
DERA -4397
CLEC4C -4506
PTPRN2 -4518
SIGLEC14 -4531
CANT1 -4584
ARHGAP9 -4589
DEGS1 -4664
PTPN6 -4696
LILRB3 -4839
CAMP -5099
STING1 -5114
PSMC3 -5134
CD36 -5161
PSMD2 -5230
PSMD6 -5301
UBR4 -5331
DOCK2 -5356
PDXK -5405
COMMD9 -5426
TOLLIP -5461
AGA -5482
KCMF1 -5542
ACAA1 -5562
ROCK1 -5718
RNASET2 -5770
ITGAV -5886
ITGAX -5891
NFASC -5983
EEF2 -6120
MPO -6131
HBB -6182
AZU1 -6184
FLG2 -6212
ACTR1B -6236
CKAP4 -6368
AOC1 -6382
OSTF1 -6440
S100A8 -6490
CTSD -6584
KRT1 -6594
DGAT1 -6603
LAMP1 -6663
HMOX2 -6697
CAPN1 -6715
SNAP25 -6741
SVIP -6786
ADAM8 -6806
SLC2A5 -6869
FUCA1 -6870
PTPRB -6922
ATP11A -6981
CAND1 -6994
ATP8A1 -7130
ACLY -7159
LTA4H -7262
DPP7 -7298
FAF2 -7322
ATP8B4 -7404
TSPAN14 -7411
ARG1 -7443
FRK -7465
ADA2 -7556
MGST1 -7618
KCNAB2 -7686
GGH -7692
GAA -7725
PSMD11 -7848
HK3 -7867
AHSG -7937
C6orf120 -8013
CHIT1 -8035
CLEC4D -8188
CHI3L1 -8239
PFKL -8341
OLFM4 -8391
VPS35L -8612
PPIE -8813
RNASE2 -8892
NHLRC3 -9119
HRNR -9182
PADI2 -9281
CST3 -9338
PIGR -9388
VCP -9523
ANPEP -9525
IMPDH2 -9591
MVP -9611
CYFIP1 -9612
CYB5R3 -9627
IGF2R -9656
PSAP -9668
PYGB -9809
ABCA13 -9831
RETN -9841
ADGRG3 -9932
LRRC7 -10028
LCN2 -10030
JUP -10136
SIRPB1 -10155
PTAFR -10164
ACP3 -10208
ORM1 -10251
S100A9 -10322
DYNC1H1 -10369
PDAP1 -10461
ALDOC -10577
RAB44 -10589
SIGLEC5 -10655
DEFA4 -10670
PKP1 -10684
LTF -10710
NBEAL2 -10742
FCN1 -10758
TTR -10853
S100P -10859
SIRPA -10931
CALML5 -10974
S100A7 -11531
ORM2 -11828
DSC1 -11859


REACTOME_RRNA_PROCESSING

REACTOME_RRNA_PROCESSING
1148
set REACTOME_RRNA_PROCESSING
setSize 192
pANOVA 3.16e-06
s.dist 0.195
p.adjustANOVA 0.000325



Top enriched genes

Top 20 genes
GeneID Gene Rank
PWP2 9896
NHP2 9205
RPS27A 9114
RRP9 9113
RPL19 8794
RPL11 8697
RPL37A 8477
MPHOSPH10 8311
RPLP1 8244
PNO1 8208
ERI1 8179
RPSA 7996
UTP6 7866
RPS7 7771
EXOSC3 7706
RPL18 7565
RPL35 7436
DIMT1 7207
RPL23 7060
RPL7 6970

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PWP2 9896.0
NHP2 9205.0
RPS27A 9114.0
RRP9 9113.0
RPL19 8794.0
RPL11 8697.0
RPL37A 8477.0
MPHOSPH10 8311.0
RPLP1 8244.0
PNO1 8208.0
ERI1 8179.0
RPSA 7996.0
UTP6 7866.0
RPS7 7771.0
EXOSC3 7706.0
RPL18 7565.0
RPL35 7436.0
DIMT1 7207.0
RPL23 7060.0
RPL7 6970.0
RPS15 6909.0
RPL26L1 6869.0
RPP40 6817.0
RPS3A 6799.0
RPS19 6793.0
PELP1 6511.0
WDR43 6353.0
NIP7 6189.0
RPL5 6098.0
TRMT10C 6096.0
RPL4 6052.0
IMP3 6015.0
UTP20 5971.0
RPL29 5923.0
WDR36 5871.0
EXOSC1 5839.0
SNU13 5796.0
RPS18 5767.0
RPS14 5716.0
BMS1 5671.0
NOP58 5533.0
FAU 5468.0
RPP21 5437.0
NOP2 5340.0
EXOSC5 5326.0
RPL12 5203.0
MRM1 5192.0
RPP14 5182.0
DCAF13 5180.0
RPS3 5150.0
ISG20L2 5046.0
CSNK1E 4963.0
RPL36 4951.0
RPL7A 4944.0
RPL27 4926.0
RPL9 4842.0
RPS26 4737.0
GNL3 4607.0
EXOSC2 4588.0
RPL17 4586.0
RPS9 4570.0
NAT10 4472.0
RPL15 4379.0
RPL31 4222.0
THUMPD1 4009.0
EXOSC4 4006.0
RPL24 4005.0
RPS8 3907.0
FTSJ3 3885.0
XRN2 3863.0
FBL 3818.0
RIOK2 3762.0
RPS29 3760.0
NCL 3745.0
DDX21 3273.0
RPP30 3093.0
RRP36 3073.0
KRR1 2942.0
RPL21 2851.0
NOP14 2847.0
RPS2 2833.0
RPS27L 2825.0
RPS6 2795.0
MTREX 2792.0
RPS15A 2682.0
RPL3 2665.0
WDR3 2654.0
RPL18A 2635.0
RPLP2 2621.0
TRMT112 2526.0
RPS5 2510.0
RPS28 2309.0
RPL35A 2159.0
RPS12 2017.0
UTP25 2014.0
RPS16 1909.0
RPP38 1831.0
RPS10 1666.0
RPL39L 1505.0
NOL11 1294.0
RPL27A 1261.0
NOL12 1235.0
PDCD11 792.0
RPL36AL 783.5
RPL3L 780.0
EMG1 773.0
NOC4L 746.0
RIOK3 743.0
RPL14 642.0
FCF1 490.0
UBA52 443.0
RPL22 335.0
RRP1 282.0
EBNA1BP2 276.0
EXOSC9 99.0
UTP11 59.0
BYSL 10.0
TEX10 -169.0
DDX47 -249.0
TSR3 -279.0
RPS25 -336.0
TSR1 -337.0
DIS3 -631.0
PES1 -642.0
RPLP0 -676.0
BUD23 -685.0
DDX49 -704.0
LTV1 -765.0
RPL6 -849.0
RPL10A -1071.0
RBM28 -1096.0
RPS23 -1524.0
RPS27 -1537.0
RPL10L -1553.0
C1D -1646.0
RPS20 -1729.0
UTP15 -1768.0
GAR1 -1844.0
RPS21 -1987.0
EXOSC8 -2115.0
WDR75 -2362.0
SENP3 -2379.0
RPL13 -2515.0
UTP4 -2595.0
RPS24 -2603.0
RPL30 -2610.0
RPL34 -2744.0
WDR46 -2768.0
NOB1 -2805.0
EXOSC6 -2976.0
RPL8 -3092.0
DDX52 -3098.0
MTERF4 -3185.0
IMP4 -3367.0
RPL32 -3472.0
WDR18 -3517.0
RPS11 -3542.0
UTP18 -3583.0
HEATR1 -3599.0
RPL37 -3656.0
BOP1 -3720.0
RCL1 -4067.0
NSUN4 -4083.0
PRORP -4234.0
WDR12 -4327.0
RPL23A -4330.0
RPL38 -4514.0
RIOK1 -4515.0
NOP10 -4814.0
TFB1M -4889.0
RPL28 -4919.0
EXOSC10 -5049.0
NOL9 -5074.0
UTP3 -5171.0
EXOSC7 -5615.0
RPL41 -5644.0
RPL22L1 -5689.0
MPHOSPH6 -6074.0
DHX37 -6648.0
RPL13A -6787.5
RPP25 -7097.0
MRM3 -7292.0
RPS13 -7476.0
RPL26 -8030.0
MRM2 -8549.0
RRP7A -8632.0
NOP56 -8858.0
CSNK1D -8860.0
NOL6 -8924.0
TBL3 -9266.0
ELAC2 -9541.0
UTP14C -10123.0


REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY

REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY
1486
set REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY
setSize 94
pANOVA 3.73e-06
s.dist 0.276
p.adjustANOVA 0.000361



Top enriched genes

Top 20 genes
GeneID Gene Rank
ATF4 9237
RPS27A 9114
ATF2 8853
RPL19 8794
RPL11 8697
TRIB3 8615
RPL37A 8477
RPLP1 8244
RPSA 7996
ASNS 7822
CEBPB 7781
RPS7 7771
RPL18 7565
RPL35 7436
IMPACT 7152
RPL23 7060
RPL7 6970
RPS15 6909
RPL26L1 6869
RPS3A 6799

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ATF4 9237.0
RPS27A 9114.0
ATF2 8853.0
RPL19 8794.0
RPL11 8697.0
TRIB3 8615.0
RPL37A 8477.0
RPLP1 8244.0
RPSA 7996.0
ASNS 7822.0
CEBPB 7781.0
RPS7 7771.0
RPL18 7565.0
RPL35 7436.0
IMPACT 7152.0
RPL23 7060.0
RPL7 6970.0
RPS15 6909.0
RPL26L1 6869.0
RPS3A 6799.0
RPS19 6793.0
RPL5 6098.0
RPL4 6052.0
RPL29 5923.0
RPS18 5767.0
RPS14 5716.0
FAU 5468.0
RPL12 5203.0
RPS3 5150.0
RPL36 4951.0
RPL7A 4944.0
RPL27 4926.0
RPL9 4842.0
RPS26 4737.0
RPL17 4586.0
RPS9 4570.0
RPL15 4379.0
RPL31 4222.0
RPL24 4005.0
RPS8 3907.0
RPS29 3760.0
RPL21 2851.0
RPS2 2833.0
RPS27L 2825.0
RPS6 2795.0
RPS15A 2682.0
RPL3 2665.0
RPL18A 2635.0
RPLP2 2621.0
RPS5 2510.0
RPS28 2309.0
RPL35A 2159.0
RPS12 2017.0
RPS16 1909.0
RPS10 1666.0
RPL39L 1505.0
RPL27A 1261.0
RPL36AL 783.5
RPL3L 780.0
EIF2S1 647.0
RPL14 642.0
UBA52 443.0
RPL22 335.0
RPS25 -336.0
CEBPG -653.0
RPLP0 -676.0
RPL6 -849.0
RPL10A -1071.0
RPS23 -1524.0
RPS27 -1537.0
RPL10L -1553.0
EIF2S2 -1726.0
RPS20 -1729.0
DDIT3 -1738.0
RPS21 -1987.0
RPL13 -2515.0
RPS24 -2603.0
RPL30 -2610.0
RPL34 -2744.0
RPL8 -3092.0
RPL32 -3472.0
RPS11 -3542.0
RPL37 -3656.0
RPL23A -4330.0
RPL38 -4514.0
RPL28 -4919.0
EIF2AK4 -5417.0
RPL41 -5644.0
RPL22L1 -5689.0
ATF3 -5834.0
RPL13A -6787.5
RPS13 -7476.0
RPL26 -8030.0
GCN1 -8821.0


REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE
1082
set REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE
setSize 125
pANOVA 7.88e-06
s.dist -0.231
p.adjustANOVA 0.000719



Top enriched genes

Top 20 genes
GeneID Gene Rank
DSC1 -11859
KRT32 -11753
SPRR3 -11670
KRT75 -11658
TGM1 -11622
KRT16 -11560
LIPK -11556
KRT15 -11470
LCE1F -11431
KRT5 -11379
KRT78 -11363
SPRR1B -11319
KRT80 -11251
KRT72 -11088
TGM5 -11052
IVL -11018
FURIN -10856
LCE2C -10854
KRT6A -10701
KRT79 -10692

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DSC1 -11859
KRT32 -11753
SPRR3 -11670
KRT75 -11658
TGM1 -11622
KRT16 -11560
LIPK -11556
KRT15 -11470
LCE1F -11431
KRT5 -11379
KRT78 -11363
SPRR1B -11319
KRT80 -11251
KRT72 -11088
TGM5 -11052
IVL -11018
FURIN -10856
LCE2C -10854
KRT6A -10701
KRT79 -10692
PKP1 -10684
KLK14 -10654
KRT81 -10615
KRT77 -10609
SPINK9 -10544
LCE6A -10385
KRT24 -10308
PKP3 -10301
PRSS8 -10168
SPRR2D -10141
JUP -10136
PI3 -10054
KLK5 -9992
ST14 -9948
CASP14 -9900
KRT82 -9758
KRT9 -9725
SPRR2E -9583
KRT13 -9549
LCE3E -9236
KRT7 -9112
KRT6B -8898
LIPJ -8895
DSC3 -8806
KRT25 -8789
KRT17 -8345
KRT73 -8259
LCE2B -8215
KRT19 -8082
DSC2 -8002
SPINK5 -7485
LCE1B -7387
KRT23 -7365
EVPL -7070
CAPN1 -6715
KRT1 -6594
PKP2 -6333
KRT26 -6187
DSG4 -6156
KRT40 -5875
SPRR2G -5550
KRT71 -5523
LCE3D -5492
PCSK6 -5365
KRT28 -5093
LCE2A -5043
PKP4 -4879
LCE4A -4858
LCE2D -4689
CELA2A -4679
KRT6C -4305
DSG3 -4287
LIPM -3828
CAPNS1 -3618
KRT84 -3510
KRT83 -3490
KLK12 -2722
KRT74 -2679
KAZN -2509
LCE1E -2078
KRT4 -1941
PERP -1759
PPL -785
CSTA -780
DSP -438
SPRR1A 1287
TCHH 1940
KRT35 2052
LCE3B 2396
DSG1 2496
LIPN 3066
KRT86 3098
KRT8 3682
KLK8 3686
SPRR2F 4037
KRT10 4140
KRT2 4298
KLK13 4618
KRT31 4664
KRT34 4901
KRT85 5119
KRT18 5212
KRT27 5431
KRT12 5526
KRT20 5730
DSG2 5749
FLG 5994
LCE1C 6321
LCE5A 6328
LCE1A 6649
KRT33A 7300
LCE3A 7978
KRT38 8175
KRT33B 8178
KRT3 8257
KRT39 8498
SPINK6 8525
SPRR2A 8943
KRT36 8987
CDSN 9283
KRT76 9327
KRT14 9400
RPTN 9421
LELP1 9425
KRT37 9622


REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL

REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL
369
set REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL
setSize 122
pANOVA 1.09e-05
s.dist 0.231
p.adjustANOVA 0.000845



Top enriched genes

Top 20 genes
GeneID Gene Rank
KLRF1 9817
SLAMF7 9791
NCR2 9760
HCST 9738
CD33 9711
TREM1 9655
SIGLEC11 9401
KLRG1 9123
LILRB4 9029
KLRB1 8988
TYROBP 8971
NCR3 8842
CD34 8824
CD300LF 8807
HLA-G 8671
CD300E 8567
SIGLEC9 8560
OSCAR 8512
CRTAM 8501
SIGLEC8 8403

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
KLRF1 9817
SLAMF7 9791
NCR2 9760
HCST 9738
CD33 9711
TREM1 9655
SIGLEC11 9401
KLRG1 9123
LILRB4 9029
KLRB1 8988
TYROBP 8971
NCR3 8842
CD34 8824
CD300LF 8807
HLA-G 8671
CD300E 8567
SIGLEC9 8560
OSCAR 8512
CRTAM 8501
SIGLEC8 8403
CLEC2D 8338
PILRA 8302
SFTPD 8215
ITGA4 8187
CD22 8173
ICAM3 8118
CD3D 7942
KLRD1 7937
LILRA2 7887
CD3E 7881
CD19 7836
CD200 7638
ITGB2 7537
SELL 7514
ICAM5 7239
LILRB2 7146
B2M 6839
CD1C 6659
CD300LB 6494
CD247 6493
KIR2DL1 6386
HLA-B 6143
LILRA3 6123
CD300LG 5991
HLA-A 5457
LILRA4 5307
HLA-C 5275
ICAM2 5140
ICAM1 4934
KIR3DL1 4922
COL1A1 4826
HLA-F 4775
ITGB7 4554
PIANP 4387
MADCAM1 4279
CD160 4063
CLEC4G 3888
COLEC12 3427
SIGLEC6 3115
CD40 3110
PVR 3101
CLEC2B 3094
SIGLEC10 2915
ULBP3 2914
MICB 2589
SIGLEC12 2530
KLRK1 2444
CD200R1 2304
SH2D1B 1728
HLA-E 1709
PILRB 1468
LAIR1 1292
TREML4 1116
C3 489
CD1D 432
JAML 80
KIR3DL2 -16
CD3G -180
NCR1 -221
MICA -598
SLAMF6 -647
CD300LD -976
CD300A -1127
CD96 -1603
ITGAL -1617
LILRB1 -1764
ICAM4 -1802
SIGLEC7 -2795
COL2A1 -3364
LILRA5 -3485
KIR2DL4 -3524
CDH1 -3562
CD226 -3691
COL1A2 -4209
ULBP1 -4694
LILRB3 -4839
NECTIN2 -4957
COL3A1 -5287
TREML2 -5290
CD81 -5520
LAIR2 -5592
CD8B -6234
CD8A -6385
NCR3LG1 -6662
LILRA1 -7026
CXADR -7648
ITGB1 -8104
COL17A1 -8125
LILRB5 -8328
VCAM1 -8629
IFITM1 -9390
CD1B -9603
CD300C -9821
SIGLEC1 -10135
NPDC1 -10419
SIGLEC5 -10655
FCGR3A -10716
KLRC1 -10831
CD1A -10961
TREM2 -11062
RAET1E -11231
TREML1 -11294


REACTOME_EUKARYOTIC_TRANSLATION_INITIATION

REACTOME_EUKARYOTIC_TRANSLATION_INITIATION
1149
set REACTOME_EUKARYOTIC_TRANSLATION_INITIATION
setSize 110
pANOVA 1.11e-05
s.dist 0.243
p.adjustANOVA 0.000845



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS27A 9114
RPL19 8794
RPL11 8697
RPL37A 8477
RPLP1 8244
EIF3K 8049
RPSA 7996
RPS7 7771
RPL18 7565
EIF3I 7471
RPL35 7436
EIF3F 7259
PABPC1 7158
RPL23 7060
RPL7 6970
EIF2B1 6961
RPS15 6909
RPL26L1 6869
RPS3A 6799
RPS19 6793

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS27A 9114.0
RPL19 8794.0
RPL11 8697.0
RPL37A 8477.0
RPLP1 8244.0
EIF3K 8049.0
RPSA 7996.0
RPS7 7771.0
RPL18 7565.0
EIF3I 7471.0
RPL35 7436.0
EIF3F 7259.0
PABPC1 7158.0
RPL23 7060.0
RPL7 6970.0
EIF2B1 6961.0
RPS15 6909.0
RPL26L1 6869.0
RPS3A 6799.0
RPS19 6793.0
EIF3J 6634.0
RPL5 6098.0
RPL4 6052.0
EIF2B2 5965.0
RPL29 5923.0
RPS18 5767.0
RPS14 5716.0
FAU 5468.0
EIF4E 5333.0
RPL12 5203.0
RPS3 5150.0
RPL36 4951.0
RPL7A 4944.0
EIF5B 4928.0
RPL27 4926.0
RPL9 4842.0
RPS26 4737.0
RPL17 4586.0
RPS9 4570.0
RPL15 4379.0
RPL31 4222.0
RPL24 4005.0
RPS8 3907.0
RPS29 3760.0
EIF3L 3031.0
RPL21 2851.0
RPS2 2833.0
RPS27L 2825.0
RPS6 2795.0
RPS15A 2682.0
RPL3 2665.0
RPL18A 2635.0
RPLP2 2621.0
RPS5 2510.0
EIF3M 2360.0
RPS28 2309.0
RPL35A 2159.0
RPS12 2017.0
RPS16 1909.0
RPS10 1666.0
RPL39L 1505.0
RPL27A 1261.0
RPL36AL 783.5
RPL3L 780.0
EIF2S1 647.0
RPL14 642.0
UBA52 443.0
RPL22 335.0
EIF4B 265.0
EIF2B4 182.0
EIF3G -321.0
RPS25 -336.0
RPLP0 -676.0
EIF4G1 -678.0
RPL6 -849.0
EIF4A2 -993.0
RPL10A -1071.0
RPS23 -1524.0
RPS27 -1537.0
RPL10L -1553.0
EIF2S2 -1726.0
RPS20 -1729.0
RPS21 -1987.0
EIF3B -2175.0
EIF3E -2232.0
RPL13 -2515.0
RPS24 -2603.0
RPL30 -2610.0
EIF2B5 -2734.0
RPL34 -2744.0
EIF3H -3036.0
RPL8 -3092.0
EIF4EBP1 -3380.0
RPL32 -3472.0
EIF2B3 -3534.0
RPS11 -3542.0
RPL37 -3656.0
EIF3A -4228.0
RPL23A -4330.0
EIF3D -4465.0
RPL38 -4514.0
RPL28 -4919.0
EIF4H -5135.0
RPL41 -5644.0
RPL22L1 -5689.0
EIF5 -5722.0
RPL13A -6787.5
EIF4A1 -6848.0
RPS13 -7476.0
RPL26 -8030.0


REACTOME_SARS_COV_2_MODULATES_HOST_TRANSLATION_MACHINERY

REACTOME_SARS_COV_2_MODULATES_HOST_TRANSLATION_MACHINERY
1601
set REACTOME_SARS_COV_2_MODULATES_HOST_TRANSLATION_MACHINERY
setSize 46
pANOVA 1.13e-05
s.dist 0.374
p.adjustANOVA 0.000845



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS27A 9114.0
SMN1 9067.5
SMN2 9067.5
GEMIN6 8546.0
SNRPD1 8497.0
RPSA 7996.0
RPS7 7771.0
SNRPF 7761.0
GEMIN2 7468.0
RPS15 6909.0
RPS3A 6799.0
RPS19 6793.0
RPS18 5767.0
RPS14 5716.0
FAU 5468.0
GEMIN5 5394.0
RPS3 5150.0
DDX20 5122.0
RPS26 4737.0
RPS9 4570.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS27A 9114.0
SMN1 9067.5
SMN2 9067.5
GEMIN6 8546.0
SNRPD1 8497.0
RPSA 7996.0
RPS7 7771.0
SNRPF 7761.0
GEMIN2 7468.0
RPS15 6909.0
RPS3A 6799.0
RPS19 6793.0
RPS18 5767.0
RPS14 5716.0
FAU 5468.0
GEMIN5 5394.0
RPS3 5150.0
DDX20 5122.0
RPS26 4737.0
RPS9 4570.0
GEMIN7 4441.0
SNRPD2 4363.0
RPS8 3907.0
RPS29 3760.0
RPS2 2833.0
RPS27L 2825.0
RPS6 2795.0
RPS15A 2682.0
RPS5 2510.0
RPS28 2309.0
RPS12 2017.0
RPS16 1909.0
RPS10 1666.0
SNRPD3 1055.0
RPS25 -336.0
SNRPG -533.0
RPS23 -1524.0
RPS27 -1537.0
SNRPE -1701.0
RPS20 -1729.0
RPS21 -1987.0
RPS24 -2603.0
SNRPB -3393.0
RPS11 -3542.0
GEMIN4 -3673.0
RPS13 -7476.0


REACTOME_MRNA_SPLICING

REACTOME_MRNA_SPLICING
1143
set REACTOME_MRNA_SPLICING
setSize 197
pANOVA 1.18e-05
s.dist 0.181
p.adjustANOVA 0.000845



Top enriched genes

Top 20 genes
GeneID Gene Rank
LSM8 9812
POLR2J 9713
LENG1 9515
CDC5L 9406
SRSF7 9328
SDE2 9189
RBM8A 9122
SMNDC1 8864
FAM32A 8836
SNRPA 8764
TRA2B 8698
SRSF10 8610
HNRNPU 8532
SNRPD1 8497
SF3B2 8224
PPIH 8061
U2AF1L4 8031
SRSF8 7851
DDX39B 7841
SNRPF 7761

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
LSM8 9812
POLR2J 9713
LENG1 9515
CDC5L 9406
SRSF7 9328
SDE2 9189
RBM8A 9122
SMNDC1 8864
FAM32A 8836
SNRPA 8764
TRA2B 8698
SRSF10 8610
HNRNPU 8532
SNRPD1 8497
SF3B2 8224
PPIH 8061
U2AF1L4 8031
SRSF8 7851
DDX39B 7841
SNRPF 7761
ZMAT2 7691
POLR2E 7472
FUS 7437
DNAJC8 7430
PRPF40A 7278
PPP1R8 7024
SNRPC 7012
ALYREF 6915
GTF2F1 6845
POLR2C 6815
U2SURP 6670
SMU1 6483
PCBP1 6452
ZNF830 6413
SF3A3 6309
CWC15 6058
SF3B6 6036
CACTIN 6032
PRCC 5988
DHX16 5960
PCBP2 5838
NSRP1 5798
SNU13 5796
SNRNP35 5795
RNPS1 5700
SRSF1 5683
DHX38 5488
POLR2K 5445
HSPA8 5412
MAGOHB 5392
PPWD1 5191
RBM7 5123
BCAS2 4924
DDX46 4918
POLR2D 4822
SNRNP27 4699
LSM3 4690
SF3B5 4408
SNRPD2 4363
SRSF2 4219
USP39 4195
SRSF6 4086
HNRNPA2B1 4066
SRSF11 3999
PDCD7 3940
SNW1 3749
PNN 3679
PPIL3 3664
HNRNPD 3447
SRSF3 3435
ISY1 3431
PPIG 3411
CASC3 3359
RBM5 3289
MAGOH 3132
PPIL2 2896
SRSF4 2891
IK 2890
LSM5 2888
MTREX 2792
RBM25 2645
HNRNPA3 2535
CWC22 2400
HNRNPA1 2369
HNRNPC 2272
NCBP2 2256
HNRNPL 2196
LUC7L3 1987
SF3A2 1844
CCDC12 1836
ZCRB1 1778
GCFC2 1733
SF1 1702
SNIP1 1569
SRSF12 1551
TXNL4A 1492
WBP11 1455
TCERG1 1391
PPIL4 1217
TFIP11 1198
PLRG1 1197
ACIN1 1138
SNRPD3 1055
C9orf78 967
HNRNPF 914
SLU7 730
PRPF4 713
RBM42 693
HNRNPK 657
LSM2 606
BUD31 527
CWC27 459
RBM17 143
PTBP1 86
DHX8 78
PRPF3 49
SUGP1 -185
DDX42 -238
SF3A1 -278
SF3B4 -380
PRPF31 -523
SNRPG -533
CDC40 -602
RBM39 -815
SAP18 -985
SRSF5 -998
NCBP1 -1089
PRPF6 -1182
DHX35 -1222
SRRT -1294
HNRNPM -1309
WDR70 -1338
POLR2I -1411
LSM4 -1511
PRKRIP1 -1570
CWF19L2 -1598
SNRPE -1701
YBX1 -1821
GTF2F2 -1855
UBL5 -1995
RNPC3 -2017
POLR2A -2108
CCAR1 -2178
LSM7 -2222
WBP4 -2263
SNRNP40 -2289
SNRNP70 -2390
SRRM1 -2414
SF3B1 -2443
EFTUD2 -2498
LSM6 -2885
CHERP -3016
PHF5A -3146
SNRPN -3175
GPATCH1 -3196
SNRPA1 -3256
SF3B3 -3258
SNRPB -3393
PRPF18 -3466
PRPF19 -3518
BUD13 -3696
SYF2 -3767
POLR2G -4059
POLR2H -4306
SNRPB2 -4342
DHX15 -4368
HNRNPH1 -4495
SNRNP25 -4583
POLR2L -4867
SNRNP200 -4979
AQR -5178
MFAP1 -5345
SRRM2 -5584
DDX41 -5604
RBM22 -5688
DDX5 -5832
POLR2F -5909
XAB2 -5969
YJU2 -6048
DDX23 -6086
HNRNPR -6181
DHX9 -6860
PRPF38A -7147
SART1 -7232
EIF4A3 -7299
PPIL1 -7347
POLR2B -7479
SRSF9 -7612
U2AF2 -7673
CRNKL1 -7760
PRPF8 -7897
CWC25 -8074
PPIE -8813
PUF60 -9798
CTNNBL1 -10303
ZMAT5 -10511
SNRNP48 -11029


REACTOME_SARS_COV_1_HOST_INTERACTIONS

REACTOME_SARS_COV_1_HOST_INTERACTIONS
1550
set REACTOME_SARS_COV_1_HOST_INTERACTIONS
setSize 92
pANOVA 1.18e-05
s.dist 0.264
p.adjustANOVA 0.000845



Top enriched genes

Top 20 genes
GeneID Gene Rank
BST2 9971
RPS27A 9114
NFKBIA 8956
PYCARD 8915
PPIB 8785
YWHAE 8616
KPNB1 8280
SFTPD 8215
TOMM70 8204
PPIH 8061
RPSA 7996
RPS7 7771
NMI 7549
PPIA 7469
TBK1 7103
UBC 6955
RPS15 6909
CASP1 6827
RPS3A 6799
RPS19 6793

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
BST2 9971
RPS27A 9114
NFKBIA 8956
PYCARD 8915
PPIB 8785
YWHAE 8616
KPNB1 8280
SFTPD 8215
TOMM70 8204
PPIH 8061
RPSA 7996
RPS7 7771
NMI 7549
PPIA 7469
TBK1 7103
UBC 6955
RPS15 6909
CASP1 6827
RPS3A 6799
RPS19 6793
IRAK2 6748
MAVS 6159
UBB 6050
PCBP2 5838
RPS18 5767
RPS14 5716
FAU 5468
ITCH 5460
FKBP1A 5202
RPS3 5150
RPS26 4737
RPS9 4570
YWHAZ 4399
NFKB1 4199
SP1 3987
RPS8 3907
RPS29 3760
YWHAB 3519
PPIG 3411
SFN 3304
TRAF6 3111
PDPK1 2962
RPS2 2833
RPS27L 2825
RPS6 2795
NPM1 2784
TRAF3 2762
RPS15A 2682
CAV1 2544
RPS5 2510
HNRNPA1 2369
RIPK3 2334
RPS28 2309
RPS12 2017
RPS16 1909
RPS10 1666
PKLR 1395
PSMC6 933
IRF3 487
UBA52 443
YWHAG 398
EEF1A1 -41
SIKE1 -70
SMAD4 -282
RPS25 -336
KPNA2 -687
RPS23 -1524
RPS27 -1537
RCAN3 -1588
UBE2I -1641
SERPINE1 -1675
RPS20 -1729
NLRP3 -1885
RPS21 -1987
RUNX1 -2356
PALS1 -2596
EP300 -2601
RPS24 -2603
RPS11 -3542
TRIM25 -3605
BCL2L1 -3748
STING1 -5114
YWHAH -5666
RIPK1 -6575
RELA -6863
RPS13 -7476
RIGI -7493
IFIH1 -7734
YWHAQ -7802
IKBKE -8990
TKFC -9057
SMAD3 -10027


REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION

REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION
151
set REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION
setSize 87
pANOVA 1.25e-05
s.dist 0.271
p.adjustANOVA 0.000854



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS27A 9114
EEF1A2 9064
EEF1G 8866
RPL19 8794
RPL11 8697
RPL37A 8477
RPLP1 8244
RPSA 7996
RPS7 7771
RPL18 7565
RPL35 7436
RPL23 7060
RPL7 6970
RPS15 6909
RPL26L1 6869
RPS3A 6799
RPS19 6793
RPL5 6098
RPL4 6052
RPL29 5923

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS27A 9114.0
EEF1A2 9064.0
EEF1G 8866.0
RPL19 8794.0
RPL11 8697.0
RPL37A 8477.0
RPLP1 8244.0
RPSA 7996.0
RPS7 7771.0
RPL18 7565.0
RPL35 7436.0
RPL23 7060.0
RPL7 6970.0
RPS15 6909.0
RPL26L1 6869.0
RPS3A 6799.0
RPS19 6793.0
RPL5 6098.0
RPL4 6052.0
RPL29 5923.0
RPS18 5767.0
RPS14 5716.0
FAU 5468.0
RPL12 5203.0
RPS3 5150.0
RPL36 4951.0
RPL7A 4944.0
RPL27 4926.0
RPL9 4842.0
RPS26 4737.0
RPL17 4586.0
RPS9 4570.0
RPL15 4379.0
RPL31 4222.0
RPL24 4005.0
RPS8 3907.0
RPS29 3760.0
EEF1B2 3063.0
RPL21 2851.0
RPS2 2833.0
RPS27L 2825.0
RPS6 2795.0
RPS15A 2682.0
RPL3 2665.0
RPL18A 2635.0
RPLP2 2621.0
RPS5 2510.0
RPS28 2309.0
RPL35A 2159.0
RPS12 2017.0
RPS16 1909.0
RPS10 1666.0
RPL39L 1505.0
RPL27A 1261.0
RPL36AL 783.5
RPL3L 780.0
RPL14 642.0
UBA52 443.0
RPL22 335.0
EEF1A1 -41.0
RPS25 -336.0
RPLP0 -676.0
RPL6 -849.0
RPL10A -1071.0
RPS23 -1524.0
RPS27 -1537.0
RPL10L -1553.0
RPS20 -1729.0
RPS21 -1987.0
RPL13 -2515.0
RPS24 -2603.0
RPL30 -2610.0
RPL34 -2744.0
RPL8 -3092.0
RPL32 -3472.0
RPS11 -3542.0
RPL37 -3656.0
RPL23A -4330.0
RPL38 -4514.0
RPL28 -4919.0
RPL41 -5644.0
RPL22L1 -5689.0
EEF2 -6120.0
RPL13A -6787.5
RPS13 -7476.0
RPL26 -8030.0
EEF1D -8406.0


REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION
116
set REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION
setSize 291
pANOVA 1.32e-05
s.dist -0.148
p.adjustANOVA 0.000869



Top enriched genes

Top 20 genes
GeneID Gene Rank
PRSS1 -11913
CAPNS2 -11745
FGA -11739
ADAMTS4 -11483
KLKB1 -11408
CAPN14 -11014
MATN3 -10862
FURIN -10856
TTR -10853
CTRB1 -10698
ASPN -10689
CTRB2 -10673
LOXL2 -10368
MMP1 -10157
FGG -10138
CAPN13 -10091
LAMB3 -9902
COL6A3 -9785
SERPINH1 -9784
MMP7 -9748

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PRSS1 -11913
CAPNS2 -11745
FGA -11739
ADAMTS4 -11483
KLKB1 -11408
CAPN14 -11014
MATN3 -10862
FURIN -10856
TTR -10853
CTRB1 -10698
ASPN -10689
CTRB2 -10673
LOXL2 -10368
MMP1 -10157
FGG -10138
CAPN13 -10091
LAMB3 -9902
COL6A3 -9785
SERPINH1 -9784
MMP7 -9748
CTSL -9733
TNR -9665
MMP16 -9663
SCUBE1 -9578
COL6A1 -9490
BMP1 -9339
LOXL1 -9319
ADAMTS2 -9155
CAPN15 -9090
COL5A1 -9067
ADAMTS5 -9024
CAPN5 -8996
SH3PXD2A -8979
ADAMTS16 -8966
ACAN -8954
MMP19 -8887
THBS1 -8840
HTRA1 -8834
ITGA11 -8815
COL23A1 -8742
FBLN1 -8741
HSPG2 -8681
VCAM1 -8629
TGFB2 -8593
PXDN -8543
CAPN2 -8422
LOXL4 -8420
PRKCA -8381
VWF -8375
ACTN1 -8362
DDR2 -8354
COL4A2 -8323
TNC -8292
COL13A1 -8286
DCN -8206
COLGALT1 -8203
SPARC -8195
ADAMTS1 -8187
COL17A1 -8125
ITGB1 -8104
COL15A1 -8068
FMOD -7905
ITGB8 -7864
FN1 -7731
MFAP2 -7675
ADAM9 -7597
SDC2 -7524
LAMB2 -7427
SCUBE3 -7403
NCAM1 -7401
CAPN3 -7354
FGB -7274
MMP14 -7254
HAPLN1 -7135
VCAN -7040
LTBP2 -7006
ITGA1 -6919
P3H1 -6892
DAG1 -6874
ADAM12 -6868
PTPRS -6857
TGFB3 -6810
ADAM8 -6806
CAPN1 -6715
DMP1 -6677
COL14A1 -6643
COL25A1 -6623
ITGA6 -6617
ADAM17 -6592
CTSD -6584
MMP17 -6578
MUSK -6558
ITGA10 -6548
ITGA2 -6482
COL22A1 -6479
A2M -6394
COL4A4 -6284
P4HA2 -6047
ITGAX -5891
ITGAV -5886
COL4A1 -5804
ITGB3 -5767
LTBP3 -5761
FBLN2 -5754
COL24A1 -5687
BMP2 -5650
TNN -5526
ITGA3 -5420
TLL1 -5399
COL5A2 -5327
COL3A1 -5287
MATN4 -5263
MMP13 -5248
ADAMTS3 -4974
BMP7 -4950
SPOCK3 -4949
COL18A1 -4835
PCOLCE2 -4807
DSPP -4749
PDGFA -4688
LAMA1 -4553
COL20A1 -4539
CAPN10 -4524
FBN1 -4474
LOXL3 -4466
ITGAD -4435
ADAM15 -4291
PLOD1 -4249
FBN2 -4245
COL1A2 -4209
LAMC1 -4096
ITGA2B -4060
EMILIN3 -3991
CAPN9 -3918
COL27A1 -3902
DST -3891
MMP3 -3882
MMP8 -3825
ADAMTS18 -3802
CAPNS1 -3618
COL9A3 -3614
ITGA8 -3603
CDH1 -3562
MMP24 -3515
LRP4 -3477
CRTAP -3448
COL2A1 -3364
ELN -3324
CD44 -3231
NRXN1 -3216
ITGB6 -3194
PHYKPL -2878
PECAM1 -2873
ITGA9 -2767
NCAN -2607
APP -2592
ADAMTS9 -2507
COL6A2 -2375
COL4A3 -2310
COL21A1 -2239
LOX -2206
LAMA3 -2137
ITGAM -2038
ITGB4 -2024
P3H3 -1962
LAMC2 -1953
ITGA5 -1842
ICAM4 -1802
LAMA2 -1754
SERPINE1 -1675
ITGAL -1617
MFAP3 -1518
EMILIN2 -1486
FBN3 -1480
MMP2 -1458
CASP3 -1454
COL10A1 -1363
NTN4 -1325
MMP10 -1163
LTBP4 -1124
CTSB -1115
ADAMTS14 -1044
OPTC -1002
PDGFB -995
PLEC -853
COL8A2 -767
F11R -576
COL6A6 -551
MATN1 -436
CAPN11 -307
ITGB5 -297
COL11A2 -281
TNXB -232
ADAMTS8 -160
P3H2 -71
CAPN8 -56
LAMC3 2
SDC1 63
EFEMP1 295
TRAPPC4 422
TIMP2 488
JAM3 516
NCSTN 536
CMA1 543
MFAP5 565
ELANE 589
COL28A1 641
CAST 699
MMP20 703
LAMB1 823
COL9A2 851
MMP15 877
KDR 916
CAPN7 979
P4HA1 1111
ITGA7 1186
TLL2 1304
JAM2 1334
FBLN5 1449
BSG 1488
P4HB 1611
PSEN1 1710
MMP11 1827
KLK7 1988
SDC4 2079
LAMA5 2177
BMP10 2281
PLOD3 2290
COL5A3 2328
NID1 2952
ITGAE 3125
LTBP1 3163
COL16A1 3173
ADAM10 3174
CD47 3342
LUM 3440
DDR1 3554
COL12A1 3663
COL6A5 3722
COL7A1 3921
PLOD2 3924
COL9A1 4008
PCOLCE 4145
NID2 4183
MADCAM1 4279
ITGB7 4554
COL19A1 4752
CEACAM8 4770
COL1A1 4826
LAMA4 4913
ICAM1 4934
MMP12 4938
BMP4 5051
COL8A1 5110
CTSK 5117
ICAM2 5140
TGFB1 5261
COL26A1 5331
PLG 5409
P4HA3 5426
CTSS 5489
MMP25 5543
EMILIN1 5647
AGRN 5753
IBSP 5810
COMP 5813
COLGALT2 5959
FGF2 5987
TMPRSS6 6300
CD151 6616
BCAN 6940
CTSG 7027
ICAM5 7239
ADAM19 7398
VTN 7424
EFEMP2 7481
SPP1 7487
KLK2 7518
ITGB2 7537
CEACAM1 7686
COL11A1 7966
ICAM3 8118
CAPN12 8163
ITGA4 8187
MFAP4 8381
CEACAM6 8636
PPIB 8785
CTSV 8822
SDC3 8909
GDF5 9059
MMP9 9692


REACTOME_SARS_COV_2_HOST_INTERACTIONS

REACTOME_SARS_COV_2_HOST_INTERACTIONS
1571
set REACTOME_SARS_COV_2_HOST_INTERACTIONS
setSize 191
pANOVA 2.4e-05
s.dist 0.177
p.adjustANOVA 0.00147



Top enriched genes

Top 20 genes
GeneID Gene Rank
IFNB1 10040.0
IFNA7 10007.0
IFNA8 9963.0
IFNA1 9879.0
IFNA2 9553.0
TUFM 9492.0
POM121 9376.0
IFNA5 9289.0
VPS18 9203.0
RPS27A 9114.0
SMN1 9067.5
SMN2 9067.5
HLA-G 8671.0
YWHAE 8616.0
GEMIN6 8546.0
SNRPD1 8497.0
NLRP12 8385.0
SFTPD 8215.0
TOMM70 8204.0
RPSA 7996.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
IFNB1 10040.0
IFNA7 10007.0
IFNA8 9963.0
IFNA1 9879.0
IFNA2 9553.0
TUFM 9492.0
POM121 9376.0
IFNA5 9289.0
VPS18 9203.0
RPS27A 9114.0
SMN1 9067.5
SMN2 9067.5
HLA-G 8671.0
YWHAE 8616.0
GEMIN6 8546.0
SNRPD1 8497.0
NLRP12 8385.0
SFTPD 8215.0
TOMM70 8204.0
RPSA 7996.0
NUP50 7809.0
NUP98 7806.0
RPS7 7771.0
SNRPF 7761.0
RAE1 7570.0
GEMIN2 7468.0
HSP90AB1 7466.0
MAP3K7 7394.0
IRF7 7249.0
TBK1 7103.0
UBC 6955.0
RPS15 6909.0
B2M 6839.0
RPS3A 6799.0
RPS19 6793.0
IRAK2 6748.0
PIK3C3 6280.0
MAVS 6159.0
HLA-B 6143.0
UBB 6050.0
NUP43 5862.0
G3BP1 5858.0
RPS18 5767.0
RPS14 5716.0
UBE2N 5648.0
IL17RC 5474.0
FAU 5468.0
HLA-A 5457.0
GEMIN5 5394.0
PTPN11 5302.0
HLA-C 5275.0
RPS3 5150.0
DDX20 5122.0
G3BP2 4828.0
HLA-F 4775.0
RPS26 4737.0
NUP35 4736.0
RIPK2 4691.0
CNBP 4640.0
RPS9 4570.0
GEMIN7 4441.0
YWHAZ 4399.0
SNRPD2 4363.0
HSP90AA1 4110.0
MASP1 4027.0
TLR2 3956.0
TRIM4 3944.0
RPS8 3907.0
RPS29 3760.0
IFNAR1 3590.0
NUP133 3541.0
YWHAB 3519.0
SFN 3304.0
CHUK 3247.0
TRAF6 3111.0
NUP85 2975.0
PDPK1 2962.0
SEC23A 2953.0
RPS2 2833.0
RPS27L 2825.0
RPS6 2795.0
TRAF3 2762.0
NUP58 2746.0
RPS15A 2682.0
NUP107 2575.0
CAV1 2544.0
RPS5 2510.0
RPS28 2309.0
TLR1 2278.0
NUP155 2265.0
RPS12 2017.0
NDC1 1928.0
RPS16 1909.0
HLA-E 1709.0
RPS10 1666.0
RANBP2 1623.0
VPS45 1620.0
AKT2 1356.0
SNRPD3 1055.0
NUP93 757.0
SAR1B 608.0
SEC13 551.0
POM121C 523.0
NUP153 497.0
IRF3 487.0
ATG14 455.0
UBA52 443.0
YWHAG 398.0
NUP88 349.0
NUP210 310.0
SIKE1 -70.0
UBE2V1 -140.0
IFNA16 -210.0
RPS25 -336.0
UVRAG -379.0
JAK1 -439.0
ISG15 -518.0
SNRPG -533.0
SEC24A -568.0
KPNA2 -687.0
NUP188 -822.0
SEC24D -884.0
IFNA13 -893.0
TPR -967.0
GJA1 -1027.0
NUP62 -1072.0
RPS23 -1524.0
RPS27 -1537.0
SEH1L -1661.0
STAT1 -1688.0
SNRPE -1701.0
RPS20 -1729.0
NUP214 -1861.0
NLRP3 -1885.0
MAP1LC3B -1955.0
RPS21 -1987.0
NUP160 -2107.0
VPS16 -2539.0
PALS1 -2596.0
RPS24 -2603.0
TJP1 -2787.0
AAAS -2886.0
TAB1 -3013.0
NUP205 -3107.0
VPS39 -3136.0
SNRPB -3393.0
RPS11 -3542.0
TRIM25 -3605.0
GEMIN4 -3673.0
NUP54 -3926.0
PATJ -4042.0
TAB2 -4232.0
SEC24C -4421.0
IFNA14 -4478.0
IFNAR2 -4571.0
SEC24B -4574.0
VPS33B -4652.0
PTPN6 -4696.0
IFNA6 -4707.0
CRB3 -4836.0
NUP42 -4844.0
STING1 -5114.0
MASP2 -5355.0
STAT2 -5418.0
YWHAH -5666.0
CREBBP -5814.0
IL17F -5914.0
VPS11 -6349.0
VPS41 -6471.0
IKBKB -6487.0
NUP37 -6563.0
RNF135 -6780.0
AKT3 -7041.0
TYK2 -7457.0
RPS13 -7476.0
RIGI -7493.0
IFIH1 -7734.0
YWHAQ -7802.0
BECN1 -8094.0
LARP1 -8096.0
VPS33A -8110.0
AKT1 -8221.0
IL17RA -8567.0
NOD1 -8854.0
IKBKE -8990.0
TKFC -9057.0
PIK3R4 -9410.0
IFNA21 -9675.0
IL17A -9947.0
NOD2 -10711.0
MBL2 -11624.0


REACTOME_CELL_CYCLE_CHECKPOINTS

REACTOME_CELL_CYCLE_CHECKPOINTS
1120
set REACTOME_CELL_CYCLE_CHECKPOINTS
setSize 284
pANOVA 2.43e-05
s.dist 0.146
p.adjustANOVA 0.00147



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC6 9443
PSMB3 9424
CENPH 9394
SGO1 9369
NBN 9219
RPS27A 9114
HUS1 8916
H4C11 8752
H2BC5 8662
BRCA1 8635
PLK1 8621
YWHAE 8616
CDC23 8438
CDC16 8398
AURKB 8361
PSMD12 8359
DYNC1LI1 8284
NUDC 8281
PSMB2 8207
CENPS 8155

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC6 9443.0
PSMB3 9424.0
CENPH 9394.0
SGO1 9369.0
NBN 9219.0
RPS27A 9114.0
HUS1 8916.0
H4C11 8752.0
H2BC5 8662.0
BRCA1 8635.0
PLK1 8621.0
YWHAE 8616.0
CDC23 8438.0
CDC16 8398.0
AURKB 8361.0
PSMD12 8359.0
DYNC1LI1 8284.0
NUDC 8281.0
PSMB2 8207.0
CENPS 8155.0
PSME1 8043.0
H4C1 7956.0
ANAPC11 7883.0
NUP98 7806.0
XPO1 7719.0
MCM5 7689.0
CDCA8 7644.0
PSMB8 7596.0
UBE2V2 7583.0
RPA2 7507.0
RHNO1 7486.0
H2BC14 7360.0
AHCTF1 7356.0
H2BC13 7347.0
RAD9B 7313.0
PSMB10 7164.0
TAOK1 7156.0
BUB1B 7137.0
MDC1 7071.0
CENPK 7007.0
H2BC3 6957.0
UBC 6955.0
DBF4 6952.0
MDM2 6908.0
CDC25C 6877.0
ORC5 6733.0
MAPRE1 6689.0
CCNB1 6675.0
H4C13 6661.0
PSMD7 6526.0
ITGB3BP 6440.0
ANAPC7 6436.0
B9D2 6429.0
NSL1 6373.0
RBBP8 6358.0
CLASP2 6327.0
PSMC2 6236.0
PSMB9 6207.0
CCNA2 6202.0
CDKN2A 6170.0
WEE1 6111.0
UBB 6050.0
KAT5 5939.0
CCNE2 5906.0
NUP43 5862.0
RAD17 5833.0
CENPT 5778.0
RCC2 5667.0
UBE2N 5648.0
CENPE 5620.0
ORC2 5616.0
PSMD5 5575.0
PSMD9 5509.0
CENPC 5500.0
CDK2 5496.0
PPP2R5B 5490.0
H4C3 5422.0
PPP1CC 5330.0
H4C9 5309.0
GTSE1 5176.0
CCNB2 5156.0
MDM4 5131.0
SGO2 5049.0
PSMA7 4962.0
BUB3 4888.0
RPA1 4760.0
ZW10 4716.0
CENPN 4680.0
ZWINT 4675.0
PSMA1 4589.0
ABRAXAS1 4565.0
MCM3 4473.0
KIF18A 4410.0
YWHAZ 4399.0
UBE2C 4308.0
PPP2CA 4197.0
CENPA 4186.0
PSMD4 4162.0
PCBP4 4051.0
H2BC12 3963.0
PSMD3 3937.0
MIS12 3918.0
PSME2 3849.0
CCNA1 3743.0
UBE2D1 3621.0
BABAM1 3581.0
NUP133 3541.0
YWHAB 3519.0
CDC6 3474.0
PAFAH1B1 3321.0
SFN 3304.0
PSMC5 3212.0
ANAPC4 3187.0
BLM 3084.0
NUP85 2975.0
PSMA5 2972.0
PPP2R5A 2860.0
PSMB4 2834.0
KNL1 2830.0
H2BC9 2696.5
PSME3 2641.0
NUP107 2575.0
BARD1 2399.0
UIMC1 2395.0
PSMA2 2366.0
RNF8 2307.0
DYNLL1 2262.0
CDC26 2182.0
EXO1 2100.0
MCM2 1927.0
MCM8 1757.0
CHEK1 1678.0
NUF2 1645.0
H2BC21 1628.0
RANBP2 1623.0
H4C4 1608.0
DSN1 1599.0
H4C16 1565.0
NDC80 1558.0
ANAPC5 1347.0
PIAS4 1272.0
RFC5 1161.0
PSMC6 933.0
CDKN1A 915.0
PSMA3 884.0
H2BC17 820.0
H4C8 810.0
RAD9A 766.0
RFC3 686.0
SEC13 551.0
RAD1 470.0
UBA52 443.0
YWHAG 398.0
CHEK2 267.0
PSMA6 176.0
COP1 42.0
H4C6 20.0
RFC4 7.0
RFC2 -124.0
PPP2R5D -128.0
PPP2R5C -164.0
SKA2 -206.0
KNTC1 -225.0
SPC25 -266.0
BUB1 -288.0
H2BC11 -531.0
WRN -532.0
CDKN1B -535.0
TP53 -582.0
SPDL1 -586.0
SPC24 -597.0
CLIP1 -605.0
ANAPC16 -645.0
DYNC1I2 -731.0
RMI1 -777.0
PMF1 -856.0
MAD2L1 -889.0
PSMD13 -945.0
CCNE1 -1098.0
SKA1 -1105.0
NDE1 -1155.0
PSMB7 -1254.0
H2BC15 -1269.0
ANAPC1 -1288.0
RAD50 -1313.0
PKMYT1 -1355.0
RPS27 -1537.0
BRIP1 -1583.0
CKAP5 -1621.0
SEH1L -1661.0
PPP2R1A -1758.0
ORC4 -1798.0
PSMC1 -1911.0
NUP160 -2107.0
ATM -2233.0
PSMB1 -2266.0
UBE2E1 -2415.0
CLASP1 -2458.0
ANAPC10 -2472.0
MCM10 -2500.0
H2BC4 -2556.0
KIF2A -2584.0
ORC3 -2778.0
PSMD1 -2969.0
PSMD14 -3064.0
PSMB6 -3169.0
MCM6 -3273.0
PSMC4 -3386.0
TP53BP1 -3473.0
BABAM2 -3487.0
MCM4 -3606.0
CDC27 -3640.0
CENPF -3728.0
PSMB5 -3729.0
DYNC1I1 -3848.0
CDC7 -3856.0
CDC20 -3888.0
HERC2 -3904.0
H2BC7 -3916.5
TOP3A -4040.0
SEM1 -4068.0
PSME4 -4304.0
NDEL1 -4470.0
NSD2 -4728.0
CENPL -4733.0
ATRIP -4739.0
CENPM -4846.0
ATR -4857.0
CLSPN -4931.0
H4C12 -4954.0
PSMC3 -5134.0
DYNC1LI2 -5155.0
PSMD2 -5230.0
PSMD6 -5301.0
PSMA8 -5314.0
RPA3 -5613.0
H2BC1 -5630.0
YWHAH -5666.0
UBE2S -5853.0
CDC45 -5943.0
CDK1 -5988.0
TOPBP1 -6112.0
PPP2R5E -6139.0
H2BC8 -6266.0
CENPU -6267.0
CDC25A -6410.0
MRE11 -6464.0
PSMD8 -6475.0
NUP37 -6563.0
CENPQ -6703.0
ORC6 -6767.0
ANAPC2 -7140.0
DNA2 -7158.0
ANAPC15 -7315.0
KIF2C -7340.0
CENPO -7459.0
MAD1L1 -7623.0
YWHAQ -7802.0
RNF168 -7813.0
PSMD11 -7848.0
ZNF385A -8139.0
ORC1 -8202.0
H4C5 -8476.0
CENPP -8633.0
H2BC10 -8762.0
H3-4 -8982.0
RMI2 -9269.0
PSMF1 -9271.0
MCM7 -9353.0
INCENP -9361.0
PPP2CB -9369.0
H2AX -9465.0
ZWILCH -9723.0
PHF20 -9928.0
H4C2 -9982.0
BIRC5 -10137.0
RANGAP1 -10242.0
H2BC26 -10312.0
DYNLL2 -10341.0
PSMA4 -10354.0
DYNC1H1 -10369.0
KIF2B -10676.0
PPP2R1B -10955.0
PSMB11 -11028.0


REACTOME_ADAPTIVE_IMMUNE_SYSTEM

REACTOME_ADAPTIVE_IMMUNE_SYSTEM
79
set REACTOME_ADAPTIVE_IMMUNE_SYSTEM
setSize 729
pANOVA 2.64e-05
s.dist 0.0914
p.adjustANOVA 0.00152



Top enriched genes

Top 20 genes
GeneID Gene Rank
TUBB8 10067
TRIM21 9851
KLRF1 9817
SLAMF7 9791
NCR2 9760
HCST 9738
CD33 9711
TREM1 9655
NRAS 9526
PSMB3 9424
SIGLEC11 9401
TRIM69 9364
BTN3A1 9217
SEC61G 9125
KLRG1 9123
RPS27A 9114
HLA-DMA 9107
SNAP23 9095
RNF182 9090
LILRB4 9029

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TUBB8 10067
TRIM21 9851
KLRF1 9817
SLAMF7 9791
NCR2 9760
HCST 9738
CD33 9711
TREM1 9655
NRAS 9526
PSMB3 9424
SIGLEC11 9401
TRIM69 9364
BTN3A1 9217
SEC61G 9125
KLRG1 9123
RPS27A 9114
HLA-DMA 9107
SNAP23 9095
RNF182 9090
LILRB4 9029
RBX1 9024
TUBB2A 9007
KLRB1 8988
TYROBP 8971
TUBB2B 8961
NFKBIA 8956
CANX 8922
SEC61B 8900
RNF4 8869
TUBA8 8859
NCR3 8842
THEM4 8837
HMGB1 8830
CD34 8824
CTSV 8822
CD300LF 8807
TUBA4B 8804
HLA-G 8671
CD79A 8650
UFL1 8628
TRIB3 8615
HLA-DQA2 8591
LAT 8576
CD300E 8567
SIGLEC9 8560
OSCAR 8512
CRTAM 8501
LAG3 8494
CDC23 8438
SIGLEC8 8403
MAP3K8 8401
CDC16 8398
PSMD12 8359
CLEC2D 8338
PILRA 8302
DYNC1LI1 8284
KIF23 8240
KIF11 8234
SFTPD 8215
PSMB2 8207
FBXL4 8206
ITGA4 8187
CD22 8173
FBXO27 8149
ICAM3 8118
DCTN5 8081
LCK 8070
PSME1 8043
CD86 7990
MEX3C 7965
PTPN22 7946
CD3D 7942
KLRD1 7937
LILRA2 7887
ANAPC11 7883
CD3E 7881
CD19 7836
CALR 7832
PDIA3 7716
PIK3R1 7701
TRIM41 7670
CD200 7638
PSMB8 7596
UBE2V2 7583
RNF7 7550
ITGB2 7537
NCK1 7516
SELL 7514
FBXO40 7498
PPIA 7469
ASB10 7395
MAP3K7 7394
ORAI1 7387
LCP2 7341
HLA-DRA 7332
ICAM5 7239
PSMB10 7164
LILRB2 7146
BTRC 7063
UBC 6955
FBXW2 6936
TRIM63 6902
SOCS1 6894
KIF5A 6860
B2M 6839
FBXL19 6811
FBXO2 6796
SMURF2 6769
FBXL15 6767
KLHL5 6668
CD1C 6659
BTNL8 6625
ASB17 6595
FBXL16 6549
PSMD7 6526
CD300LB 6494
CD247 6493
BCL10 6486
PIK3R3 6443
ANAPC7 6436
BTN1A1 6398
KIR2DL1 6386
CD74 6364
TRPC1 6346
FBXW9 6336
KIF3A 6291
PIK3C3 6280
KCTD7 6249
ACTR10 6248
PSMC2 6236
KIF3B 6216
SYK 6209
PSMB9 6207
HLA-B 6143
UBE2D2 6124
LILRA3 6123
TRIM36 6106
DNM1 6082
UBB 6050
KLHL42 5992
CD300LG 5991
GLMN 5983
FBXO17 5977
TUBB3 5910
RNF114 5857
ORAI2 5844
CCNF 5811
LRRC41 5766
RILP 5729
UBE2N 5648
INPP5D 5633
TUBA4A 5624
CENPE 5620
PAK1 5615
MALT1 5591
PSMD5 5575
BTBD1 5567
RAB7A 5536
TAP1 5516
PSMD9 5509
PRKACG 5493
PPP2R5B 5490
CTSS 5489
GRB2 5484
ITCH 5460
RNF41 5459
HLA-A 5457
HLA-DRB1 5396
UBE3A 5379
UBE2G1 5377
AP2S1 5363
NCF2 5334
RNF111 5327
LILRA4 5307
PTPN11 5302
FBXO4 5293
HLA-C 5275
HLA-DOA 5221
FKBP1A 5202
ICAM2 5140
UBE2R2 5118
CTSK 5117
ZNRF2 5044
PTPRJ 5029
UBE2M 5026
HLA-DMB 5000
FBXL18 4992
RAP1A 4971
PSMA7 4962
CTSA 4961
FBXL12 4943
ICAM1 4934
KIR3DL1 4922
FYB1 4907
COL1A1 4826
HLA-F 4775
RIPK2 4691
FBXO22 4656
RNF14 4622
SEC31A 4613
PSMA1 4589
ITGB7 4554
UBE2W 4502
FBXO11 4492
TUBB4A 4471
LYN 4456
KIF18A 4410
YWHAZ 4399
PIANP 4387
BTLA 4374
FBXO10 4331
ZBTB16 4326
UBE2C 4308
IFI30 4293
MADCAM1 4279
UBR2 4245
UBE2U 4230
PPP3R1 4210
NFKB1 4199
PPP2CA 4197
KIF5B 4191
HLA-DPA1 4165
PSMD4 4162
UBE4A 4138
DCTN2 4113
UBE2D3 4105
MYD88 4093
KIF15 4067
KLHL20 4065
CD160 4063
VHL 4024
ASB8 4022
KLHL9 3995
TLR2 3956
KBTBD7 3950
TRIM4 3944
PSMD3 3937
ITK 3903
CLEC4G 3888
RASGRP2 3879
PSME2 3849
SIAH2 3834
UBE2Q2 3814
WSB1 3800
CLTA 3740
ASB3 3713
HERC6 3661
RBCK1 3651
DZIP3 3633
RICTOR 3622
UBE2D1 3621
AP2B1 3536
YWHAB 3519
CUL1 3500
RNF126 3454
COLEC12 3427
TLR4 3376
PIK3CD 3305
PDCD1LG2 3280
DAPP1 3275
CHUK 3247
LGMN 3229
PSMC5 3212
ANAPC4 3187
UBA5 3136
LNPEP 3135
SIGLEC6 3115
TRAF6 3111
CD40 3110
PVR 3101
CLEC2B 3094
UBE2E2 2978
PSMA5 2972
PDPK1 2962
FBXO7 2955
SEC23A 2953
ERAP2 2930
FBXO30 2925
KLHL21 2918
SIGLEC10 2915
ULBP3 2914
RCHY1 2907
KLHL41 2905
PPP2R5A 2860
PSMB4 2834
TRIP12 2831
TLR6 2822
TRAT1 2811
CTLA4 2752
VAV1 2695
DTX3L 2649
PSME3 2641
MICB 2589
AP1M2 2550
DCTN6 2549
BTN3A3 2534
SIGLEC12 2530
FBXW12 2524
ANAPC13 2509
PJA2 2468
KLRK1 2444
CD14 2408
PAG1 2398
TUBB4B 2387
PSMA2 2366
RASGRP3 2318
CD200R1 2304
UBE2K 2283
TLR1 2278
DYNLL1 2262
CDC26 2182
LRR1 2107
BLK 2106
TUBA3E 2102
TUBA1A 2084
UBE2B 2022
ARF1 2006
CUL2 1955
STIM1 1942
DCAF1 1924
AP1S3 1899
FBXW7 1809
SH2D1B 1728
HECTD1 1714
CTSH 1711
HLA-E 1709
HLA-DPB1 1625
HLA-DRB5 1572
KLHL2 1515
TRIM9 1509
PILRB 1468
DET1 1443
UBE2L3 1435
HERC5 1394
LTN1 1364
AKT2 1356
ANAPC5 1347
LAIR1 1292
TIRAP 1286
HSPA5 1259
RBBP6 1254
FBXW11 1250
ENAH 1247
KRAS 1227
RNF138 1221
RNF19B 1181
UNKL 1132
TREML4 1116
AHCYL1 1088
PIK3CA 1054
RNF25 1048
RAC1 1036
WWP1 937
PSMC6 933
RNF130 909
PSMA3 884
PAK2 871
RNF34 849
SEC61A1 794
AP1M1 724
LY96 705
REL 669
KLHL11 611
SAR1B 608
SEC13 551
GRAP2 542
PTEN 524
C3 489
ATG14 455
UBA52 443
CD1D 432
HLA-DQB1 327
VASP 307
PLCG2 293
FBXL3 272
PIK3AP1 221
ASB15 191
PSMA6 176
CD101 169
RNF19A 124
RAP1GAP2 101
UBE2H 94
JAML 80
FBXW8 21
UBA6 19
KIR3DL2 -16
FBXL20 -29
PPP2R5D -128
UBE2V1 -140
PPP2R5C -164
CD3G -180
NCR1 -221
CLTC -241
PRKACB -259
TRIM37 -260
ITGB5 -297
UBE3C -360
BTNL2 -364
PIK3CB -397
KLC3 -410
CAPZA1 -421
KLHL22 -560
SEC24A -568
ATG7 -578
MICA -598
HERC1 -633
CUL3 -638
SLAMF6 -647
LONRF1 -673
NFATC3 -713
DYNC1I2 -731
BLMH -755
STX4 -766
CD28 -775
PPL -785
AP2A2 -802
PRKG1 -825
SEC24D -884
ZNRF1 -939
PSMD13 -945
CD300LD -976
RAP1B -1066
CTSB -1115
CD300A -1127
RAP1GAP -1191
AREL1 -1202
ASB13 -1221
PSMB7 -1254
STUB1 -1276
FBXL8 -1281
ANAPC1 -1288
NFKBIB -1345
SPSB2 -1404
FBXW4 -1531
SRC -1560
VAMP8 -1575
CD96 -1603
ITGAL -1617
PTPRC -1663
HECW2 -1705
PPP2R1A -1758
LILRB1 -1764
ASB2 -1781
ICAM4 -1802
MAP3K14 -1836
FBXO15 -1845
PSMC1 -1911
UBE3D -1914
TUBA1B -1967
UBE2J1 -2004
TAPBP -2037
MIB2 -2067
KCTD6 -2091
KLC1 -2122
PSMB1 -2266
CALM1 -2269
SOCS3 -2291
CTSO -2342
UBE2E1 -2415
UBAC1 -2437
ANAPC10 -2472
ASB16 -2476
FBXO9 -2524
KIF2A -2584
RNF144B -2651
TRAF7 -2688
CD209 -2710
DNM2 -2711
FBXL7 -2717
YES1 -2729
UBR1 -2752
UBA3 -2765
KIF3C -2790
SIGLEC7 -2795
MGRN1 -2807
RNF220 -2835
FBXO6 -2913
UBE2D4 -2952
PSMD1 -2969
PSMD14 -3064
PRKCB -3067
KIF20A -3085
CTSC -3090
EVL -3094
KEAP1 -3117
PSMB6 -3169
SEC22B -3229
PRR5 -3237
PRKCQ -3299
CDC42 -3304
ASB14 -3328
SH3GL2 -3345
COL2A1 -3364
PSMC4 -3386
CYBA -3462
LILRA5 -3485
KIR2DL4 -3524
LMO7 -3533
CDH1 -3562
KLC4 -3580
CDC27 -3640
CD226 -3691
CD80 -3697
PSMB5 -3729
CD4 -3736
DYNC1I1 -3848
HRAS -3869
KIF22 -3876
CDC20 -3888
HERC2 -3904
PIK3R2 -3958
CAPZA3 -3967
PPP3CB -3976
FYN -4031
RNF6 -4046
SEM1 -4068
OSBPL1A -4157
DNM3 -4195
COL1A2 -4209
TAB2 -4232
PPP3CA -4250
MKRN1 -4266
FBXO44 -4289
PSME4 -4304
UBOX5 -4317
TAP2 -4323
CDC34 -4340
FBXL14 -4364
SEC24C -4421
AP1B1 -4432
NEDD4 -4460
CUL5 -4482
UBE3B -4522
SEC24B -4574
TUBB6 -4579
RAF1 -4601
AP1G1 -4624
DCTN4 -4639
UBE2G2 -4677
ULBP1 -4694
PTPN6 -4696
VAMP3 -4768
UBE2O -4782
LILRB3 -4839
PLCG1 -4850
NFATC2 -4920
NECTIN2 -4957
UBE2E3 -4991
RNF115 -5065
PSMC3 -5134
NFATC1 -5147
DYNC1LI2 -5155
CD36 -5161
UBE2J2 -5169
FBXO21 -5192
PSMD2 -5230
ZAP70 -5238
SIAH1 -5239
FBXO31 -5252
ITPR1 -5255
COL3A1 -5287
TREML2 -5290
PSMD6 -5301
PSMA8 -5314
UBR4 -5331
ELOB -5434
MLST8 -5446
CD81 -5520
SPSB1 -5576
ASB7 -5577
LAIR2 -5592
FBXW5 -5606
S100A1 -5611
MYLIP -5686
UBE2Z -5755
UBA7 -5794
CSK -5824
CBLB -5843
KIFAP3 -5847
UBE2S -5853
ASB5 -5869
ITGAV -5886
FZR1 -5912
SPTBN2 -5994
PRKN -5995
DCTN1 -6015
HLA-DQB2 -6036
PRKACA -6093
TUBA3C -6096
PPP2R5E -6139
HACE1 -6142
RASGRP1 -6213
CD8B -6234
ACTR1B -6236
CD8A -6385
ITPR2 -6404
ACTR1A -6470
PSMD8 -6475
RACGAP1 -6481
IKBKB -6487
S100A8 -6490
CTSD -6584
CAPZB -6607
SPSB4 -6637
NCR3LG1 -6662
KBTBD8 -6771
BTN3A2 -6825
TUBA1C -6828
RELA -6863
FBXL22 -6905
MRC2 -6936
SKP2 -6950
TPP2 -6955
KIF26A -7015
LILRA1 -7026
AKT3 -7041
BTN2A1 -7058
TUBAL3 -7065
PDCD1 -7090
TRIM11 -7138
ANAPC2 -7140
HERC3 -7143
TRIM39 -7182
HLA-DOB -7216
SKP1 -7268
FGB -7274
UBE2Q1 -7334
RAPGEF4 -7335
SH3RF1 -7337
KIF2C -7340
FBXL13 -7359
SMURF1 -7502
CXADR -7648
ARIH2 -7696
BTNL9 -7706
ASB6 -7774
TRIM71 -7787
ELOC -7792
CTSF -7800
SIPA1 -7810
LRSAM1 -7824
NPEPPS -7837
PSMD11 -7848
RAPGEF3 -7863
HLA-DQA1 -7910
KLHL25 -7912
CD274 -7951
UBE2L6 -7975
MAPKAP1 -8046
AP2A1 -8058
TRIM50 -8071
BECN1 -8094
ITGB1 -8104
HERC4 -8118
COL17A1 -8125
RNF123 -8183
AKT1 -8221
ASB1 -8244
HECTD3 -8254
SOS1 -8309
UBE2F -8320
LILRB5 -8328
CD207 -8329
GAN -8344
LNX1 -8451
ICOS -8574
ERAP1 -8591
CARD11 -8606
TRAIP -8618
VCAM1 -8629
NEDD4L -8705
SEC61A2 -8925
HECTD2 -8945
BTN2A2 -8946
RNF213 -8986
ITPR3 -8994
KLC2 -9116
NFKBIE -9140
CAPZA2 -9218
PSMF1 -9271
KBTBD6 -9343
AP2M1 -9366
PPP2CB -9369
IFITM1 -9390
MTOR -9408
PIK3R4 -9410
THOP1 -9419
FBXW10 -9500
CD1B -9603
FBXL5 -9629
NCF4 -9660
CTSE -9690
CTSL -9733
ASB4 -9746
TUBB1 -9794
CD300C -9821
AP1S1 -9854
TRIM32 -9998
DCTN3 -10034
CUL7 -10088
SIGLEC1 -10135
FGG -10138
BLNK -10145
FBXO32 -10204
KIF4B -10310
S100A9 -10322
DYNLL2 -10341
PSMA4 -10354
DYNC1H1 -10369
CD79B -10378
NPDC1 -10419
KLHL3 -10514
SIGLEC5 -10655
KIF2B -10676
FCGR3A -10716
RNF217 -10722
ASB18 -10734
KLRC1 -10831
PPP2R1B -10955
CD1A -10961
PSMB11 -11028
TREM2 -11062
XDH -11153
RAET1E -11231
TREML1 -11294
BTBD6 -11312
TUBA3D -11433
FBXO41 -11534
FGA -11739


REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION
1161
set REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION
setSize 1336
pANOVA 2.71e-05
s.dist 0.0684
p.adjustANOVA 0.00152



Top enriched genes

Top 20 genes
GeneID Gene Rank
ZNF732 9796
ZNF619 9732
POLR2J 9713
SP7 9704
SPI1 9703
NR2F1 9623
ZNF37A 9597
BGLAP 9594
CR1 9560
ZNF738 9510
ZNF658 9487
TTC5 9473
IGFBP1 9465
H2BC6 9443
PSMB3 9424
GAMT 9357
SRSF7 9328
ZNF662 9312
NBN 9219
COX5A 9214

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ZNF732 9796.0
ZNF619 9732.0
POLR2J 9713.0
SP7 9704.0
SPI1 9703.0
NR2F1 9623.0
ZNF37A 9597.0
BGLAP 9594.0
CR1 9560.0
ZNF738 9510.0
ZNF658 9487.0
TTC5 9473.0
IGFBP1 9465.0
H2BC6 9443.0
PSMB3 9424.0
GAMT 9357.0
SRSF7 9328.0
ZNF662 9312.0
NBN 9219.0
COX5A 9214.0
ZNF285 9176.0
ZNF596 9175.0
PMS2 9173.0
RBM8A 9122.0
POMC 9118.0
RPS27A 9114.0
ZNF429 9093.0
ZNF470 9048.0
NR0B2 9041.0
NFE2 9030.0
RBX1 9024.0
ZNF770 9002.0
ZNF584 8976.0
HUS1 8916.0
NUDT21 8884.0
SOX2 8872.0
H3C12 8871.0
ZNF528 8856.0
ATF2 8853.0
ZNF621 8845.0
CTSV 8822.0
LMO2 8781.0
PIP4P1 8776.0
H4C11 8752.0
ZNF786 8741.0
ZNF675 8687.0
H2BC5 8662.0
BRCA1 8635.0
GADD45A 8631.0
YWHAE 8616.0
PRKAG1 8590.0
JUNB 8582.0
GTF2B 8573.0
COX6B1 8566.0
ZNF564 8565.0
ZNF439 8555.0
EAF2 8549.0
MEAF6 8531.0
UCMA 8500.0
ZNF543 8480.0
CDC23 8438.0
H3C6 8421.0
TFAP2B 8418.0
CDC16 8398.0
AURKB 8361.0
PSMD12 8359.0
SYMPK 8342.0
ZNF431 8326.0
ZNF671 8282.0
ZNF620 8248.0
ZNF70 8242.0
ZNF730 8233.0
NLRC4 8218.0
PSMB2 8207.0
ITGA4 8187.0
ZNF570 8148.0
NDUFA4 8146.0
ZNF624 8140.0
TRIM28 8059.0
PSME1 8043.0
CLP1 8035.0
ZNF546 8032.0
U2AF1L4 8031.0
ZNF726 7986.0
NR4A2 7975.0
LAMTOR2 7974.0
H4C1 7956.0
ZNF227 7954.0
ZNF446 7936.0
MTA2 7912.0
ANAPC11 7883.0
ZNF771 7850.0
DDX39B 7841.0
CCNH 7837.0
ZNF684 7829.0
LSM11 7805.0
ZNF200 7792.0
CEBPB 7781.0
TXNIP 7779.0
SNRPF 7761.0
SKIL 7754.0
ZNF214 7728.0
XPO1 7719.0
G6PC1 7624.0
H3-3A 7620.0
TXN 7617.0
GPRIN1 7610.0
COX19 7600.0
PSMB8 7596.0
ZNF747 7580.0
ZNF700 7573.0
CCNC 7566.0
CITED2 7543.0
ZNF175 7538.0
RPA2 7507.0
ZIM2 7501.0
TNFRSF10B 7494.0
SPP1 7487.0
RHNO1 7486.0
POLR2E 7472.0
ARNT 7467.0
ZNF707 7465.0
PVALB 7458.0
ZNF343 7457.0
RBM14 7450.0
E2F5 7446.0
ZNF383 7441.0
ZNF676 7432.0
ZNF354C 7425.0
CCNG1 7408.0
ATXN3 7389.0
GTF2H3 7363.0
H2BC14 7360.0
TEAD2 7349.0
H2BC13 7347.0
ZNF202 7343.0
ACTL6B 7337.0
ZNF287 7334.0
CCND3 7333.0
ZNF33A 7324.0
RAD9B 7313.0
TWIST1 7307.0
ZNF790 7289.0
ZNF670 7233.0
ZNF354A 7217.0
PPP1R13L 7206.0
TFAP2A 7166.0
PSMB10 7164.0
MYL9 7140.0
ZNF627 7127.0
PIN1 7112.0
ZNF692 7105.0
INTS7 7091.0
COX20 7088.0
E2F1 7078.0
MDC1 7071.0
RFFL 7068.0
MAML1 7056.0
DDIT4 7046.0
SMARCD2 7037.0
FASLG 7002.0
ELF1 6990.0
H3C3 6984.0
ZNF615 6983.0
H2BC3 6957.0
UBC 6955.0
INTS2 6941.0
ZFP69B 6919.0
ALYREF 6915.0
MDM2 6908.0
TRIM63 6902.0
CDC25C 6877.0
AGO1 6854.0
TPX2 6848.0
GTF2F1 6845.0
ZNF333 6841.0
KAT6A 6838.0
ZNF75A 6834.0
BBC3 6831.0
CASP1 6827.0
DLX5 6818.0
POLR2C 6815.0
RNU11 6783.0
SMURF2 6769.0
ZFP90 6758.0
PRDX1 6756.0
LAMTOR5 6743.0
FOXO1 6731.0
ZNF746 6724.0
DDX39A 6712.0
HEY1 6697.0
H2AC4 6694.0
APOE 6687.0
CCNB1 6675.0
ZNF716 6671.0
H4C13 6661.0
CCNG2 6653.0
THOC1 6646.0
ZNF737 6639.0
TAF6 6633.0
ZFP28 6628.0
ZNF566 6598.0
ZNF430 6541.0
PSMD7 6526.0
ZNF155 6525.0
SNAPC5 6505.0
GTF2A2 6500.0
HAND2 6468.0
ZNF425 6455.0
MED30 6454.0
ANAPC7 6436.0
MGA 6403.0
ZNF112 6387.0
ZNF724 6377.0
SESN2 6366.0
RBBP8 6358.0
H2AZ2 6310.0
YEATS4 6251.0
CDK6 6242.0
PSMC2 6236.0
TAF10 6230.0
PSMB9 6207.0
CCNA2 6202.0
NR2C2 6192.0
POU4F1 6185.0
CDKN2A 6170.0
RPAP2 6166.0
ZNF420 6148.0
L3MBTL1 6092.0
PABPN1 6091.0
MED20 6090.0
GPAM 6066.0
COX14 6064.0
HEY2 6061.0
UBB 6050.0
ZNF713 6029.0
ZNF860 6025.0
ICE1 6005.0
ZNF100 5998.0
PMAIP1 5978.0
CBFB 5976.0
MED31 5952.0
ZKSCAN5 5948.0
ZNF208 5946.0
ZNF569 5943.0
KAT5 5939.0
EZH2 5934.0
ZNF33B 5914.0
PPARA 5911.0
CCNE2 5906.0
RYBP 5899.0
SOD2 5896.0
SMARCC2 5895.0
CSTF1 5887.0
NR4A1 5855.0
RAD17 5833.0
RAD51 5785.0
PCGF5 5770.0
MEN1 5742.0
RNPS1 5700.0
SRSF1 5683.0
TAF9 5675.0
NR2C2AP 5674.0
NR4A3 5672.0
NELFCD 5652.0
SMARCE1 5618.0
ZNF493 5617.0
ZNF212 5599.0
LMO1 5584.0
PSMD5 5575.0
ZNF205 5544.0
ZNF697 5537.0
H3C1 5532.0
ZNF25 5523.0
LAMTOR1 5521.0
NR2F6 5517.0
GTF2E1 5511.0
PSMD9 5509.0
ZNF703 5508.0
CDK2 5496.0
DHX38 5488.0
CDK4 5483.0
ITCH 5460.0
BMI1 5453.0
ZNF394 5448.0
POLR2K 5445.0
SNAPC1 5444.0
RARG 5423.0
H4C3 5422.0
THOC3 5410.0
TGIF2 5398.0
MAGOHB 5392.0
ZNF254 5375.0
NOP2 5340.0
RNF111 5327.0
H4C9 5309.0
PTPN11 5302.0
ZNF517 5299.0
CPSF6 5295.0
CBX8 5279.0
TGFB1 5261.0
BTG1 5251.0
COX7A2L 5194.0
ZNF180 5187.0
ZNF311 5161.0
H3-3B 5160.0
MDM4 5131.0
CLDN5 5128.0
CTSK 5117.0
CBX5 5060.0
SRF 5054.0
NR5A2 5033.0
CCND2 5007.0
FAS 5002.0
COX5B 4990.0
ZNF778 4981.0
LEO1 4978.0
PSMA7 4962.0
NR1I2 4946.0
PRKAB1 4896.0
RBL1 4892.0
IL6 4886.0
PRELID1 4876.0
COL1A1 4826.0
POLR2D 4822.0
ZNF708 4817.0
CNOT6L 4797.0
CRADD 4789.0
ZNF273 4768.0
RPA1 4760.0
ZNF140 4757.0
GPI 4733.0
MED7 4732.0
ACTL6A 4719.0
ZNF20 4714.0
ELL3 4701.0
TP73 4662.0
SMARCA2 4647.0
SIN3A 4610.0
PTPN1 4609.0
KMT5A 4591.0
PSMA1 4589.0
ZNF473 4578.0
TGIF1 4509.0
NR1D2 4485.0
ZNF839 4439.0
NR2E1 4435.0
TACO1 4412.0
YAP1 4411.0
YWHAZ 4399.0
INTS8 4367.0
TAF15 4327.0
UBE2C 4308.0
LBR 4294.0
ZNF597 4290.0
CNOT9 4248.0
PAF1 4246.0
CAMK4 4233.0
BAX 4223.0
SRSF2 4219.0
NFKB1 4199.0
PPP2CA 4197.0
PSMD4 4162.0
SUPT16H 4157.0
ZKSCAN8 4146.0
ZNF549 4129.0
ZNF688 4125.0
SKIC8 4122.0
COX18 4115.0
ZNF607 4108.0
UBE2D3 4105.0
SRSF6 4086.0
MIR137 4060.0
PCBP4 4051.0
H2AC14 4031.0
EED 4026.0
SRSF11 3999.0
SP1 3987.0
PITX2 3984.0
PAPOLA 3964.0
H2BC12 3963.0
H3C10 3945.0
ZNF14 3941.0
PSMD3 3937.0
GAD2 3883.0
AURKA 3878.0
PCK1 3860.0
PSME2 3849.0
TP53INP1 3841.0
IL2RA 3813.0
MEF2C 3788.0
MLH1 3782.0
NELFA 3769.0
TBL1XR1 3761.0
SNW1 3749.0
CCNA1 3743.0
ZNF583 3726.0
SUMO1 3699.0
ZNF324B 3689.0
RICTOR 3622.0
UBE2D1 3621.0
INTS6 3588.0
BRD1 3547.0
ZNF419 3537.0
SNAPC3 3533.0
CCNK 3525.0
YWHAB 3519.0
GLI3 3514.0
ARID3A 3512.0
TBX5 3505.0
ZNF331 3503.0
CUL1 3500.0
RBBP4 3444.0
GLS 3441.0
SRSF3 3435.0
ZNF649 3429.0
SETD1B 3425.0
NOTCH4 3419.0
ZNF230 3409.0
GATA4 3405.0
TP53RK 3375.0
CASC3 3359.0
SMARCD3 3338.0
TRIAP1 3311.0
SFN 3304.0
TXNRD1 3303.0
BNIP3L 3290.0
IWS1 3281.0
GAD1 3269.0
CNOT3 3264.0
CTR9 3240.0
PLAGL1 3234.0
PSMC5 3212.0
NR1H3 3198.0
ANAPC4 3187.0
PPARG 3164.0
ZNF799 3155.0
RBPJ 3151.0
MAGOH 3132.0
ZNF484 3119.0
BLM 3084.0
ARID2 3067.0
ZNF782 3065.0
CPSF7 3055.0
SMARCB1 3053.0
INTS3 3051.0
AGO3 3026.0
RNMT 3008.0
PSMA5 2972.0
PINK1 2968.0
PDPK1 2962.0
ZNF79 2961.0
CPSF2 2928.0
PIP4K2A 2906.0
ZNF141 2894.0
SRSF4 2891.0
PSMB4 2834.0
DYRK2 2819.0
CDK12 2801.0
ZNF559 2793.0
NPM1 2784.0
ZNF17 2776.0
RNF2 2754.0
CTLA4 2752.0
HIPK1 2750.0
ZNF571 2744.0
HDAC3 2742.0
ZNF709 2735.0
NRBP1 2712.0
NCOR1 2709.0
H2BC9 2696.5
H3C7 2696.5
ZNF302 2688.0
CPSF1 2683.0
E2F8 2681.0
PSME3 2641.0
DDB2 2640.0
SUPT4H1 2627.0
CDK7 2611.0
RARB 2584.0
ZNF791 2581.0
CCNT2 2573.0
H3C11 2569.0
CASP10 2564.0
TAF12 2556.0
CAV1 2544.0
GATAD2B 2518.0
KAT2B 2494.0
CAMK2D 2474.0
INS 2434.0
ZNF729 2432.0
BCL2L14 2431.0
IL2 2429.0
HDAC2 2417.0
DPY30 2413.0
BARD1 2399.0
CPSF3 2377.0
INTS10 2376.0
PSMA2 2366.0
INTS14 2358.0
NR2C1 2357.0
ZNF804B 2322.0
ABCA6 2302.0
ZKSCAN3 2297.0
NCBP2 2256.0
ZNF479 2255.0
ZNF350 2227.0
TAF13 2220.0
BRPF1 2215.0
CDC26 2182.0
BCL6 2176.0
ZNF442 2146.0
GPS2 2142.0
BLK 2106.0
THRA 2105.0
EXO1 2100.0
ELL2 2098.0
JAG1 2093.0
ZNF143 2089.0
ZNF678 2081.0
DLX6 2078.0
ZNF398 2070.0
INTS9 2061.0
TCF7L1 2032.0
ZNF43 2025.0
ERCC3 2011.0
ZNF875 2009.0
ZFP69 2005.0
HSPD1 1978.0
FKBP5 1971.0
ZNF136 1962.0
ZNF680 1961.0
SARNP 1954.0
NABP2 1945.0
IHH 1943.0
ZNF235 1896.0
PBRM1 1892.0
TCEA1 1869.0
TEAD3 1838.0
ZNF234 1837.0
TAF5 1834.0
FBXW7 1809.0
ZNF226 1791.0
NABP1 1789.0
PCGF6 1716.0
TRPC3 1715.0
CCN2 1708.0
SST 1706.0
BRD2 1703.0
EHMT1 1700.0
MYB 1697.0
GLS2 1695.0
ELOA 1693.0
TFDP2 1681.0
CHEK1 1678.0
E2F6 1655.0
KDM5B 1644.0
H2BC21 1628.0
H4C4 1608.0
TAF4B 1592.0
LDB1 1589.0
H4C16 1565.0
NPAS4 1564.0
PCNA 1539.0
THOC6 1537.0
ASH2L 1513.0
ZNF3 1479.0
RBL2 1478.0
ZNF248 1463.0
ZNF552 1457.0
ZNF626 1456.0
ZFPM1 1419.0
SSU72 1410.0
RPRD1A 1378.0
AKT2 1356.0
ZNF124 1353.0
ANAPC5 1347.0
NR3C1 1306.0
ZNF616 1302.0
BCL2L11 1271.0
ZNF540 1260.0
KRAS 1227.0
ZNF138 1222.0
TAF3 1202.0
PLK2 1180.0
CNOT2 1168.0
RFC5 1161.0
IGFBP3 1155.0
PPARD 1154.0
RABGGTB 1151.0
ZNF565 1146.0
NR1D1 1115.0
MNAT1 1110.0
SNRPD3 1055.0
SMAD2 1051.0
CGB8 1041.0
HNF4A 1033.0
NKX3-2 1005.0
FYTTD1 999.0
CSNK2A1 972.0
RGCC 969.0
H3C4 958.0
WWP1 937.0
PPM1D 935.0
PSMC6 933.0
PRMT6 930.0
CDKN1A 915.0
BRD7 904.0
KMT2C 889.0
PSMA3 884.0
CSF1R 870.0
TP53I3 866.0
RNF34 849.0
ZNF268 839.0
ZNF567 832.0
RARA 828.0
H2BC17 820.0
H4C8 810.0
COX6A1 806.0
RAD9A 766.0
ZNF577 750.0
IQSEC3 748.0
OPRM1 738.0
ICE2 732.0
SLU7 730.0
AXIN1 698.0
RFC3 686.0
ZNF189 675.0
CHD4 671.0
CREB1 643.0
RORB 618.0
GTF2H1 604.0
ITGBL1 596.0
FANCI 591.0
MIR132 590.0
HDAC5 585.0
INTS13 581.0
TNFRSF18 559.0
ZNF710 557.0
ZNF655 532.0
PTEN 524.0
CBX2 514.0
RAD1 470.0
SYT10 450.0
RXRB 449.0
UBA52 443.0
FOXG1 441.0
YWHAG 398.0
MAPK11 394.0
FIP1L1 322.0
RXRG 294.0
CHEK2 267.0
PHC3 263.0
STK11 235.0
SATB2 228.0
CDK5 212.0
SOCS4 210.0
ELF2 200.0
NR6A1 194.0
PSMA6 176.0
POU2F1 166.0
TFAP2E 156.0
MSX2 153.0
KAT2A 151.0
NELFE 115.0
ARID1A 87.0
APAF1 73.0
RPRD2 64.0
TAF11 58.0
OCLN 35.0
GSK3B 32.0
MIR24-2 31.0
ESR1 29.0
H4C6 20.0
RFC4 7.0
ZNF557 3.0
TP53BP2 -32.0
ZNF764 -39.0
ZNF547 -44.0
CDK13 -59.0
BDNF -60.0
ESR2 -94.0
SNAPC2 -115.0
RFC2 -124.0
PPP2R5C -164.0
ZNF506 -170.0
BID -171.0
SCMH1 -205.0
ZC3H8 -216.0
TAF8 -237.0
EPC1 -280.0
SMAD4 -282.0
ZC3H11A -302.0
GRIN2B -311.0
JUN -329.0
CNOT6 -332.0
ZNF667 -341.0
MED13 -343.0
ZNF99 -347.0
PLK3 -351.0
YAF2 -356.0
SMARCD1 -370.0
PRKAG3 -371.0
ZNF215 -375.0
TSC1 -392.0
ZNF669 -411.0
CBX3 -413.0
CAMK2B -425.0
SUPT5H -457.0
TCF3 -497.0
H2BC11 -531.0
WRN -532.0
SNRPG -533.0
CDKN1B -535.0
TP53 -582.0
RSPO3 -596.0
CDC40 -602.0
HTT -622.0
YY1 -625.0
AGRP -637.0
ANAPC16 -645.0
ESRRA -686.0
ZKSCAN4 -689.0
KMT2A -737.0
BTG2 -739.0
DAXX -744.0
SCO1 -746.0
THOC7 -749.0
MLLT3 -752.0
PHC1 -764.0
RMI1 -777.0
COX6C -803.0
TNRC6A -826.0
ZNF599 -832.0
SESN3 -861.0
ZNF668 -870.0
SMAD7 -929.0
NRBF2 -938.0
PSMD13 -945.0
PRDM7 -963.0
ZFP30 -981.0
MED6 -996.0
SRSF5 -998.0
SURF1 -1031.0
MED23 -1033.0
ZNF233 -1058.0
SLC2A3 -1084.0
NCBP1 -1089.0
CCNE1 -1098.0
ZNF222 -1164.0
CNOT10 -1214.0
PPARGC1A -1226.0
TCF7L2 -1242.0
PSMB7 -1254.0
TCF12 -1257.0
H2BC15 -1269.0
STUB1 -1276.0
ZNF28 -1282.0
RRAGC -1286.0
ANAPC1 -1288.0
SRRT -1294.0
SESN1 -1296.0
RAD50 -1313.0
PRDM1 -1314.0
CSNK2B -1315.0
ZNF611 -1324.0
SIRT1 -1339.0
PARP1 -1343.0
DLL1 -1356.0
SMAD6 -1400.0
ZNF267 -1405.0
POLR2I -1411.0
SLBP -1442.0
COX4I1 -1446.0
ZNF699 -1451.0
ZNF483 -1457.0
RRM2B -1481.0
ZNF701 -1520.0
SRC -1560.0
BRIP1 -1583.0
PRMT1 -1587.0
PRELID3A -1604.0
ITGAL -1617.0
UBE2I -1641.0
PF4 -1645.0
SERPINE1 -1675.0
USP7 -1680.0
STAT1 -1688.0
RRAGD -1695.0
NFYA -1696.0
SNRPE -1701.0
DDIT3 -1738.0
MSH2 -1748.0
PPP2R1A -1758.0
PERP -1759.0
NFYB -1774.0
BRPF3 -1785.0
ZNF740 -1812.0
MAP2K6 -1817.0
YBX1 -1821.0
NR3C2 -1824.0
ZKSCAN1 -1835.0
THRB -1838.0
ITGA5 -1842.0
GTF2F2 -1855.0
SETD1A -1875.0
ZNF426 -1876.0
COX7C -1892.0
ZNF555 -1902.0
PSMC1 -1911.0
MAPK1 -1913.0
VDR -1932.0
GATAD2A -1942.0
CITED4 -1972.0
RUNX2 -1983.0
CAT -1996.0
BANP -2027.0
ZNF691 -2031.0
PCF11 -2051.0
RTF1 -2087.0
KCTD6 -2091.0
POLR2A -2108.0
RNGTT -2153.0
ZSCAN32 -2155.0
LIFR -2164.0
GTF2H4 -2167.0
ING2 -2202.0
ATM -2233.0
ZNF568 -2236.0
SIRT3 -2262.0
PSMB1 -2266.0
CALM1 -2269.0
PTPN4 -2275.0
SOCS3 -2291.0
CYCS -2296.0
LRPPRC -2315.0
CENPJ -2333.0
RUNX1 -2356.0
RBFOX3 -2406.0
ZNF418 -2412.0
SRRM1 -2414.0
UBE2E1 -2415.0
SUPT6H -2430.0
MED24 -2471.0
ANAPC10 -2472.0
ZNF706 -2474.0
MAPK14 -2491.0
PIP4K2B -2501.0
ZNF304 -2518.0
ZNF18 -2522.0
ZNF184 -2541.0
ZNF460 -2548.0
AGO4 -2550.0
CRH -2555.0
H2BC4 -2556.0
ZNF223 -2562.0
EP300 -2601.0
INTS12 -2623.0
MYBL2 -2635.0
TCF7 -2656.0
H2AC20 -2685.0
PAX5 -2692.0
LGALS3 -2703.0
YES1 -2729.0
ZNF263 -2755.0
TJP1 -2787.0
SMARCC1 -2811.0
ZNF19 -2813.0
ZNF10 -2815.0
RORC -2858.0
CASP2 -2871.0
ZNF224 -2888.0
CSTF2T -2890.0
PSMD1 -2969.0
ZNF554 -3019.0
SGK1 -3028.0
ZNF792 -3034.0
ZNF510 -3041.0
PSMD14 -3064.0
PRKCB -3067.0
RING1 -3069.0
ZNF582 -3080.0
GTF2A1 -3089.0
HES1 -3101.0
ZNF436 -3134.0
ZNF440 -3137.0
ZNF454 -3156.0
THOC5 -3161.0
PSMB6 -3169.0
ZFP2 -3172.0
ZNF77 -3186.0
PRR5 -3237.0
SLC38A9 -3259.0
CNOT4 -3263.0
ZNF727 -3289.0
PRKCQ -3299.0
MAML3 -3342.0
PIP4K2C -3343.0
NPPA -3344.0
ZNF586 -3350.0
ZNF561 -3358.0
RB1 -3379.0
PSMC4 -3386.0
SNRPB -3393.0
FOS -3394.0
TNRC6C -3416.0
ZNF461 -3423.0
HDAC9 -3450.0
H3C2 -3460.0
PRDX5 -3461.0
ESRRB -3498.0
MIR27A -3516.0
VEGFA -3556.0
ZNF471 -3559.0
CHTOP -3569.0
FANCD2 -3587.0
TNFRSF10D -3610.0
ZNF324 -3621.0
CDC27 -3640.0
CDC73 -3664.0
IFNG -3683.0
ZNF793 -3692.0
PSMB5 -3729.0
CCND1 -3790.0
ZNF445 -3810.0
H2AC6 -3847.0
CDC7 -3856.0
SMYD2 -3859.0
GATA2 -3873.0
TBP -3880.0
H2AC7 -3916.5
H2BC7 -3916.5
ZNF496 -3922.0
ELL -3930.0
CNOT7 -3994.0
LAMTOR3 -4002.0
CBX4 -4005.0
NPY -4008.0
TOP3A -4040.0
ZNF660 -4050.0
POLR2G -4059.0
ITGA2B -4060.0
ZNF721 -4062.0
ZNF563 -4064.0
PRKAA2 -4065.0
SEM1 -4068.0
WDR33 -4088.0
CAMK2G -4110.0
NELFB -4126.0
ZNF211 -4152.0
ZNF681 -4170.0
TGFA -4202.0
TAF2 -4207.0
SETD9 -4208.0
COL1A2 -4209.0
KLF4 -4210.0
NOC2L -4233.0
USP2 -4236.0
CBX6 -4241.0
PSME4 -4304.0
POLR2H -4306.0
PRKAB2 -4318.0
GATA3 -4320.0
MBD3 -4372.0
TRIM33 -4380.0
GRIN2A -4411.0
ZNF614 -4418.0
ZNF485 -4461.0
ZNF530 -4486.0
MYC -4492.0
ZNF560 -4501.0
RPRD1B -4502.0
ZNF114 -4576.0
CPSF4 -4580.0
EAF1 -4619.0
ZNF772 -4629.0
LEF1 -4643.0
ZNF317 -4656.0
TNRC6B -4685.0
CNOT1 -4686.0
CASP6 -4716.0
ZNF521 -4727.0
ATRIP -4739.0
INTS11 -4744.0
INTS1 -4753.0
POU2F2 -4754.0
STEAP3 -4755.0
ZNF354B -4769.0
MAPKAPK5 -4806.0
ATR -4857.0
ZNF587 -4863.0
POLR2L -4867.0
ZNF264 -4869.0
ZNF761 -4896.0
ING5 -4911.0
NFATC2 -4920.0
MED17 -4941.0
H4C12 -4954.0
PGR -4959.0
SKI -4960.0
GTF2E2 -4968.0
HDAC7 -4970.0
TP63 -4985.0
MED8 -5063.0
DEK -5084.0
KMT2E -5101.0
PSMC3 -5134.0
SIN3B -5144.0
ESRRG -5149.0
RBFOX1 -5153.0
GRIA2 -5168.0
ZNF282 -5185.0
ZFHX3 -5191.0
ZNF600 -5203.0
CCNT1 -5207.0
GCK -5217.0
PSMD2 -5230.0
MMP13 -5248.0
HDAC11 -5249.0
ZNF551 -5256.0
TEAD1 -5285.0
ZNF735 -5291.0
PSMD6 -5301.0
PSMA8 -5314.0
ZNF573 -5330.0
HIPK2 -5346.0
RET -5391.0
ZNF704 -5407.0
HDAC10 -5410.0
TMEM219 -5433.0
ELOB -5434.0
NOTCH3 -5441.0
MLST8 -5446.0
RNU12 -5447.0
NDRG1 -5448.0
ZNF610 -5454.0
TIGAR -5459.0
HNF4G -5473.0
RHEB -5497.0
ZNF677 -5499.0
ZNF500 -5501.0
PHAX -5594.0
PRMT5 -5599.0
VENTX -5603.0
RPA3 -5613.0
H2BC1 -5630.0
MED1 -5634.0
BMP2 -5650.0
ZNF544 -5656.0
YWHAH -5666.0
RORA -5694.0
TFAP2D -5752.0
ZNF347 -5757.0
PPM1A -5786.0
CREBBP -5814.0
UBE2S -5853.0
MED4 -5856.0
ZNF718 -5862.0
ZNF585B -5905.0
POLR2F -5909.0
FZR1 -5912.0
ZNF529 -5913.0
MOBP -5919.0
AFF4 -5942.0
ZNF550 -5956.0
RRAGA -5987.0
CDK1 -5988.0
H2AZ1 -5992.0
ARID1B -6029.0
RRM2 -6030.0
MED16 -6031.0
ERCC2 -6042.0
TFDP1 -6067.0
PRKACA -6093.0
TOPBP1 -6112.0
EGFR -6149.0
H2AC18 -6150.5
H2AC19 -6150.5
ZNF257 -6175.0
ZNF253 -6178.0
ZNF773 -6183.0
KIT -6252.0
ZNF266 -6261.0
H2BC8 -6266.0
MET -6270.0
ZNF432 -6313.0
ZNF441 -6325.0
NKX2-5 -6331.0
NR5A1 -6351.0
GTF2H5 -6365.0
RBBP5 -6374.0
ZNF664 -6387.0
CTNNB1 -6403.0
INTS5 -6412.0
ZNF562 -6422.0
ZNF274 -6432.0
ZNF785 -6439.0
MRE11 -6464.0
PSMD8 -6475.0
SCO2 -6488.0
NFYC -6495.0
ZNF133 -6506.0
ZNF169 -6537.0
COX11 -6547.0
MAML2 -6569.0
ZNF195 -6630.0
L3MBTL2 -6651.0
ZNF679 -6675.0
ZKSCAN7 -6683.0
NR1I3 -6699.0
PRKAG2 -6701.0
PCGF2 -6705.0
MED10 -6718.0
LAMTOR4 -6744.0
ZNF585A -6769.0
ZNF689 -6775.0
ZNF334 -6800.0
ZNF213 -6815.0
RELA -6863.0
NCOR2 -6882.0
ZNF665 -6910.0
CNOT11 -6912.0
SOX9 -6917.0
MED27 -6918.0
ZNF101 -6920.0
WWTR1 -6931.0
CDK8 -6933.0
CAMK2A -6942.0
SKP2 -6950.0
ELOA2 -6968.0
ZNF225 -6971.0
SUZ12 -6992.0
ZNF160 -7010.0
H3C8 -7012.0
AKT3 -7041.0
ZNF23 -7067.0
LSM10 -7075.0
NR1H2 -7107.0
ZNF696 -7119.0
ANAPC2 -7140.0
AUTS2 -7154.0
DNA2 -7158.0
H2AC8 -7163.0
CDK9 -7173.0
PIDD1 -7212.0
H2AJ -7223.0
RABGGTA -7238.0
ZNF197 -7240.0
MED26 -7256.0
SKP1 -7268.0
EIF4A3 -7299.0
ANAPC15 -7315.0
INTS4 -7324.0
ZNF92 -7346.0
ZNF613 -7348.0
PPARGC1B -7349.0
AGO2 -7367.0
NR1H4 -7402.0
FOXO3 -7416.0
ZNF382 -7445.0
POLR2B -7479.0
CNOT8 -7480.0
TSC2 -7497.0
SMURF1 -7502.0
NAMPT -7505.0
MAPK3 -7509.0
TAF1L -7562.0
TAL1 -7577.0
KRBOX5 -7606.0
SRSF9 -7612.0
SMARCA4 -7614.0
ZNF514 -7620.0
CARM1 -7660.0
ZIM3 -7661.0
U2AF2 -7673.0
KRBA1 -7683.0
MOV10 -7688.0
ZNF490 -7701.0
ZNF714 -7723.0
TFAP2C -7742.0
ZNF415 -7747.0
ELOC -7792.0
YWHAQ -7802.0
SMAD1 -7825.0
ZNF625 -7836.0
PSMD11 -7848.0
KCTD1 -7855.0
CSTF3 -7860.0
HIVEP3 -7871.0
ABL1 -7906.0
ZNF480 -7914.0
FANCC -7938.0
MED25 -7950.0
SSRP1 -7963.0
ZNF777 -7997.0
EHMT2 -8019.0
MAPKAP1 -8046.0
HDAC4 -8072.0
ERBB2 -8105.0
RAD51D -8107.0
TEAD4 -8114.0
ZFP1 -8129.0
ZNF385A -8139.0
ZNF416 -8150.0
CTDP1 -8164.0
ZNF776 -8172.0
ZNF154 -8194.0
KCNIP3 -8196.0
AKT1 -8221.0
ZNF26 -8224.0
ZNF641 -8234.0
RUNX3 -8253.0
ZNF443 -8316.0
GLI2 -8342.0
REST -8409.0
MIR24-1 -8423.0
H4C5 -8476.0
ZNF492 -8480.0
ZNF774 -8490.0
SNAPC4 -8500.0
ZNF250 -8546.0
ZSCAN25 -8568.0
PRDX2 -8598.0
ZNF2 -8627.0
ZNF34 -8634.0
NUAK1 -8646.0
ZIK1 -8663.0
JMY -8696.0
NEDD4L -8705.0
ZNF256 -8713.0
H2BC10 -8762.0
KCTD15 -8769.0
ZNF682 -8779.0
NOTCH1 -8791.0
PML -8810.0
THBS1 -8840.0
TNFRSF10A -8842.0
ZNF556 -8890.0
ZFP14 -8930.0
ZNF286A -8947.0
ATAD2 -8984.0
ZNF337 -9027.0
MED15 -9030.0
ZNF548 -9034.0
TNFRSF10C -9035.0
BMAL1 -9056.0
POLDIP3 -9089.0
CSNK2A2 -9111.0
RXRA -9113.0
SREBF1 -9122.0
E2F4 -9152.0
AIFM2 -9154.0
ZNF30 -9190.0
WWOX -9198.0
MAF -9249.0
RMI2 -9269.0
PSMF1 -9271.0
TNKS1BP1 -9306.0
ZNF433 -9331.0
PPP2CB -9369.0
ZNF606 -9380.0
E2F7 -9389.0
ZNF135 -9403.0
MTOR -9408.0
MAX -9412.0
ZNF300 -9431.0
ZNF71 -9437.0
PRKAA1 -9441.0
PPP1R13B -9444.0
H2AX -9465.0
ZNF486 -9471.0
HDAC1 -9524.0
COX8A -9589.0
ZNF74 -9615.0
ZNF749 -9621.0
PHC2 -9673.0
DGCR8 -9701.0
PLXNA4 -9702.0
ZNF417 -9709.0
ZFP37 -9728.0
CTSL -9733.0
ZNF775 -9762.0
RPTOR -9795.0
RETN -9841.0
COX16 -9862.0
MSTN -9894.0
ZNF45 -9907.0
ZNF221 -9924.0
PHF20 -9928.0
CDKN2B -9939.0
H4C2 -9982.0
OPRK1 -9990.0
SMAD3 -10027.0
CHD3 -10070.0
ZNF12 -10078.0
BIRC5 -10137.0
FBXO32 -10204.0
TAF4 -10218.0
TWIST2 -10247.0
TAF7 -10262.0
KMT2B -10300.0
ZNF558 -10311.0
H2BC26 -10312.0
PSMA4 -10354.0
ZNF468 -10372.0
POU4F2 -10388.0
ARNT2 -10400.0
WDR5 -10409.0
ZNF595 -10449.0
GEM -10462.0
ZNF320 -10553.0
ZNF605 -10571.0
CDK5R1 -10573.0
SERPINB13 -10585.0
FOXO6 -10590.0
GSR -10612.0
RNU4ATAC -10657.0
NR2E3 -10707.0
ZNF589 -10709.0
MLLT1 -10847.0
FURIN -10856.0
CSF2 -10880.0
GPX2 -10921.0
ZNF519 -10924.0
PPP2R1B -10955.0
PSMB11 -11028.0
NOTCH2 -11147.0
KMT2D -11274.0
ZNF750 -11304.0
CGB5 -11321.0
ZNF736 -11381.0
TP53AIP1 -11432.0
CGA -11499.0
ZNF717 -11527.0
IL3 -11651.0
GP1BA -11823.0


REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS

REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS
1364
set REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS
setSize 161
pANOVA 2.79e-05
s.dist 0.191
p.adjustANOVA 0.00152



Top enriched genes

Top 20 genes
GeneID Gene Rank
PSMB3 9424
RBM8A 9122
RPS27A 9114
RBX1 9024
RPL19 8794
RPL11 8697
RPL37A 8477
PSMD12 8359
RPLP1 8244
PSMB2 8207
PSME1 8043
RPSA 7996
RPS7 7771
PSMB8 7596
RPL18 7565
RPL35 7436
PSMB10 7164
PABPC1 7158
LHX9 7133
RPL23 7060

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PSMB3 9424.0
RBM8A 9122.0
RPS27A 9114.0
RBX1 9024.0
RPL19 8794.0
RPL11 8697.0
RPL37A 8477.0
PSMD12 8359.0
RPLP1 8244.0
PSMB2 8207.0
PSME1 8043.0
RPSA 7996.0
RPS7 7771.0
PSMB8 7596.0
RPL18 7565.0
RPL35 7436.0
PSMB10 7164.0
PABPC1 7158.0
LHX9 7133.0
RPL23 7060.0
RPL7 6970.0
UBC 6955.0
RPS15 6909.0
RPL26L1 6869.0
RPS3A 6799.0
RPS19 6793.0
PSMD7 6526.0
PSMC2 6236.0
PSMB9 6207.0
RPL5 6098.0
RPL4 6052.0
UBB 6050.0
RPL29 5923.0
RPS18 5767.0
RPS14 5716.0
RNPS1 5700.0
PSMD5 5575.0
PSMD9 5509.0
FAU 5468.0
MAGOHB 5392.0
RPL12 5203.0
RPS3 5150.0
PSMA7 4962.0
RPL36 4951.0
RPL7A 4944.0
RPL27 4926.0
UPF3A 4844.0
RPL9 4842.0
LHX2 4840.0
RPS26 4737.0
PSMA1 4589.0
RPL17 4586.0
RPS9 4570.0
GSPT1 4461.0
RPL15 4379.0
RPL31 4222.0
PSMD4 4162.0
RPL24 4005.0
PSMD3 3937.0
RPS8 3907.0
PSME2 3849.0
RPS29 3760.0
CASC3 3359.0
PSMC5 3212.0
MAGOH 3132.0
PSMA5 2972.0
RPL21 2851.0
PSMB4 2834.0
RPS2 2833.0
RPS27L 2825.0
RPS6 2795.0
RPS15A 2682.0
RPL3 2665.0
PSME3 2641.0
RPL18A 2635.0
RPLP2 2621.0
RPS5 2510.0
PSMA2 2366.0
RPS28 2309.0
NCBP2 2256.0
RPL35A 2159.0
RPS12 2017.0
CUL2 1955.0
USP33 1934.0
RPS16 1909.0
RPS10 1666.0
LDB1 1589.0
RPL39L 1505.0
RPL27A 1261.0
PSMC6 933.0
PSMA3 884.0
RPL36AL 783.5
RPL3L 780.0
RPL14 642.0
UBA52 443.0
RPL22 335.0
UPF2 232.0
PSMA6 176.0
ROBO1 -139.0
RPS25 -336.0
RPLP0 -676.0
EIF4G1 -678.0
RPL6 -849.0
PSMD13 -945.0
RPL10A -1071.0
NCBP1 -1089.0
PSMB7 -1254.0
ROBO3 -1279.0
RPS23 -1524.0
RPS27 -1537.0
RPL10L -1553.0
RPS20 -1729.0
PSMC1 -1911.0
RPS21 -1987.0
PSMB1 -2266.0
RPL13 -2515.0
RPS24 -2603.0
RPL30 -2610.0
RPL34 -2744.0
PSMD1 -2969.0
HOXA2 -3006.0
PSMD14 -3064.0
SLIT2 -3072.0
RPL8 -3092.0
PSMB6 -3169.0
PSMC4 -3386.0
RPL32 -3472.0
RPS11 -3542.0
SLIT1 -3600.0
RPL37 -3656.0
PSMB5 -3729.0
ROBO2 -4048.0
SEM1 -4068.0
ISL1 -4102.0
PSME4 -4304.0
RPL23A -4330.0
RPL38 -4514.0
RPL28 -4919.0
MSI1 -4921.0
PSMC3 -5134.0
PSMD2 -5230.0
PSMD6 -5301.0
PSMA8 -5314.0
ELOB -5434.0
RPL41 -5644.0
RPL22L1 -5689.0
PSMD8 -6475.0
ETF1 -6665.0
RPL13A -6787.5
DAG1 -6874.0
LHX4 -7106.0
EIF4A3 -7299.0
RPS13 -7476.0
ELOC -7792.0
PSMD11 -7848.0
RPL26 -8030.0
PSMF1 -9271.0
ZSWIM8 -10317.0
PSMA4 -10354.0
LHX3 -10408.0
PSMB11 -11028.0


REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE

REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE
500
set REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE
setSize 228
pANOVA 3.76e-05
s.dist 0.158
p.adjustANOVA 0.00199



Top enriched genes

Top 20 genes
GeneID Gene Rank
TUBB8 10067
PSMB3 9424
CENPH 9394
POM121 9376
SGO1 9369
RPS27A 9114
TUBB2A 9007
TUBB2B 8961
TUBA8 8859
TUBA4B 8804
PLK1 8621
CDC23 8438
CDC16 8398
AURKB 8361
PSMD12 8359
DYNC1LI1 8284
NUDC 8281
KPNB1 8280
PSMB2 8207
CENPS 8155

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TUBB8 10067
PSMB3 9424
CENPH 9394
POM121 9376
SGO1 9369
RPS27A 9114
TUBB2A 9007
TUBB2B 8961
TUBA8 8859
TUBA4B 8804
PLK1 8621
CDC23 8438
CDC16 8398
AURKB 8361
PSMD12 8359
DYNC1LI1 8284
NUDC 8281
KPNB1 8280
PSMB2 8207
CENPS 8155
CHMP4C 8102
PSME1 8043
ANAPC11 7883
NUP98 7806
XPO1 7719
CDCA8 7644
PSMB8 7596
AHCTF1 7356
WAPL 7310
PSMB10 7164
TAOK1 7156
BUB1B 7137
CENPK 7007
UBC 6955
MAPRE1 6689
CCNB1 6675
SPAST 6582
PSMD7 6526
ITGB3BP 6440
ANAPC7 6436
CHMP3 6434
B9D2 6429
NSL1 6373
CLASP2 6327
PSMC2 6236
PSMB9 6207
UBB 6050
TUBB3 5910
NUP43 5862
CENPT 5778
RCC2 5667
TUBA4A 5624
CENPE 5620
PSMD5 5575
PSMD9 5509
CENPC 5500
PPP2R5B 5490
PPP1CC 5330
CCNB2 5156
CHMP7 5154
SGO2 5049
PSMA7 4962
BUB3 4888
NUP35 4736
ZW10 4716
CENPN 4680
ZWINT 4675
PSMA1 4589
PDS5B 4580
PPP2R2A 4552
SIRT2 4482
TUBB4A 4471
RAD21 4470
KIF18A 4410
UBE2C 4308
LBR 4294
FBXO5 4225
PPP2CA 4197
CENPA 4186
PSMD4 4162
CDCA5 4091
RCC1 3988
PSMD3 3937
MIS12 3918
PSME2 3849
SUMO1 3699
UBE2D1 3621
NUP133 3541
TMPO 3353
PAFAH1B1 3321
PSMC5 3212
ANAPC4 3187
NUP85 2975
PSMA5 2972
PPP2R5A 2860
PSMB4 2834
KNL1 2830
TNPO1 2826
NUP58 2746
PSME3 2641
NUP107 2575
TUBB4B 2387
PSMA2 2366
NUP155 2265
DYNLL1 2262
VRK2 2183
CDC26 2182
TUBA3E 2102
TUBA1A 2084
PDS5A 2067
NDC1 1928
CHMP2A 1810
NUF2 1645
RANBP2 1623
DSN1 1599
NDC80 1558
LEMD3 1447
ANAPC5 1347
PTTG1 1236
PSMC6 933
STAG1 896
PSMA3 884
NUP93 757
IST1 616
SEC13 551
UBA52 443
CHMP2B 392
PSMA6 176
PPP2R5D -128
PPP2R5C -164
SKA2 -206
KNTC1 -225
SPC25 -266
BUB1 -288
SPDL1 -586
SPC24 -597
CLIP1 -605
ANKLE2 -623
ANAPC16 -645
DYNC1I2 -731
NUP188 -822
PMF1 -856
MAD2L1 -889
PSMD13 -945
NUP62 -1072
SKA1 -1105
NDE1 -1155
PSMB7 -1254
ANAPC1 -1288
CC2D1B -1512
RPS27 -1537
CHMP4A -1606
CKAP5 -1621
UBE2I -1641
SEH1L -1661
LMNA -1752
PPP2R1A -1758
PSMC1 -1911
TUBA1B -1967
LMNB1 -2007
NUP160 -2107
PSMB1 -2266
UBE2E1 -2415
CLASP1 -2458
ANAPC10 -2472
KIF2A -2584
PSMD1 -2969
PSMD14 -3064
NUP205 -3107
PSMB6 -3169
PSMC4 -3386
CDC27 -3640
VPS4A -3688
CENPF -3728
PSMB5 -3729
DYNC1I1 -3848
CDC20 -3888
NUP54 -3926
SEM1 -4068
PSME4 -4304
ESPL1 -4329
RAN -4355
NDEL1 -4470
TUBB6 -4579
CENPL -4733
CENPM -4846
SMC3 -5110
PSMC3 -5134
DYNC1LI2 -5155
PSMD2 -5230
PSMD6 -5301
BANF1 -5310
PSMA8 -5314
CHMP6 -5445
VRK1 -5641
UBE2S -5853
CDK1 -5988
TUBA3C -6096
PPP2R5E -6139
CENPU -6267
PSMD8 -6475
NUP37 -6563
CENPQ -6703
TUBA1C -6828
TUBAL3 -7065
ANAPC2 -7140
ANAPC15 -7315
KIF2C -7340
CENPO -7459
MAD1L1 -7623
PSMD11 -7848
CENPP -8633
CHMP4B -8861
LEMD2 -9150
PSMF1 -9271
INCENP -9361
PPP2CB -9369
ZWILCH -9723
TUBB1 -9794
BIRC5 -10137
RANGAP1 -10242
DYNLL2 -10341
PSMA4 -10354
DYNC1H1 -10369
KIF2B -10676
PPP2R1B -10955
PSMB11 -11028
TUBA3D -11433


REACTOME_TCR_SIGNALING

REACTOME_TCR_SIGNALING
391
set REACTOME_TCR_SIGNALING
setSize 113
pANOVA 6.44e-05
s.dist 0.218
p.adjustANOVA 0.0033



Top enriched genes

Top 20 genes
GeneID Gene Rank
PSMB3 9424
RPS27A 9114
NFKBIA 8956
HLA-DQA2 8591
LAT 8576
PSMD12 8359
PSMB2 8207
LCK 8070
PSME1 8043
PTPN22 7946
CD3D 7942
CD3E 7881
PIK3R1 7701
PSMB8 7596
NCK1 7516
MAP3K7 7394
LCP2 7341
HLA-DRA 7332
PSMB10 7164
BTRC 7063

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PSMB3 9424
RPS27A 9114
NFKBIA 8956
HLA-DQA2 8591
LAT 8576
PSMD12 8359
PSMB2 8207
LCK 8070
PSME1 8043
PTPN22 7946
CD3D 7942
CD3E 7881
PIK3R1 7701
PSMB8 7596
NCK1 7516
MAP3K7 7394
LCP2 7341
HLA-DRA 7332
PSMB10 7164
BTRC 7063
UBC 6955
PSMD7 6526
CD247 6493
BCL10 6486
PSMC2 6236
PSMB9 6207
UBE2D2 6124
UBB 6050
UBE2N 5648
INPP5D 5633
PAK1 5615
MALT1 5591
PSMD5 5575
PSMD9 5509
HLA-DRB1 5396
PTPRJ 5029
PSMA7 4962
FYB1 4907
RIPK2 4691
PSMA1 4589
NFKB1 4199
HLA-DPA1 4165
PSMD4 4162
PSMD3 3937
ITK 3903
PSME2 3849
UBE2D1 3621
CUL1 3500
CHUK 3247
PSMC5 3212
TRAF6 3111
PSMA5 2972
PDPK1 2962
PSMB4 2834
TRAT1 2811
PSME3 2641
PAG1 2398
PSMA2 2366
HLA-DPB1 1625
HLA-DRB5 1572
FBXW11 1250
ENAH 1247
PIK3CA 1054
PSMC6 933
PSMA3 884
PAK2 871
GRAP2 542
PTEN 524
UBA52 443
HLA-DQB1 327
VASP 307
PLCG2 293
PSMA6 176
CD101 169
UBE2V1 -140
CD3G -180
PIK3CB -397
PSMD13 -945
PSMB7 -1254
PTPRC -1663
PSMC1 -1911
PSMB1 -2266
PSMD1 -2969
PSMD14 -3064
EVL -3094
PSMB6 -3169
PRKCQ -3299
PSMC4 -3386
PSMB5 -3729
CD4 -3736
PIK3R2 -3958
SEM1 -4068
TAB2 -4232
PSME4 -4304
CDC34 -4340
PLCG1 -4850
PSMC3 -5134
PSMD2 -5230
ZAP70 -5238
PSMD6 -5301
PSMA8 -5314
CSK -5824
HLA-DQB2 -6036
PSMD8 -6475
IKBKB -6487
RELA -6863
SKP1 -7268
PSMD11 -7848
HLA-DQA1 -7910
CARD11 -8606
PSMF1 -9271
PSMA4 -10354
PSMB11 -11028


REACTOME_SARS_COV_1_INFECTION

REACTOME_SARS_COV_1_INFECTION
1539
set REACTOME_SARS_COV_1_INFECTION
setSize 136
pANOVA 6.7e-05
s.dist 0.198
p.adjustANOVA 0.00333



Top enriched genes

Top 20 genes
GeneID Gene Rank
BST2 9971
RPS27A 9114
NFKBIA 8956
PARP8 8931
CANX 8922
PYCARD 8915
PPIB 8785
YWHAE 8616
KPNB1 8280
SFTPD 8215
TOMM70 8204
CHMP4C 8102
PPIH 8061
RPSA 7996
RPS7 7771
NMI 7549
PPIA 7469
TBK1 7103
UBC 6955
RPS15 6909

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
BST2 9971
RPS27A 9114
NFKBIA 8956
PARP8 8931
CANX 8922
PYCARD 8915
PPIB 8785
YWHAE 8616
KPNB1 8280
SFTPD 8215
TOMM70 8204
CHMP4C 8102
PPIH 8061
RPSA 7996
RPS7 7771
NMI 7549
PPIA 7469
TBK1 7103
UBC 6955
RPS15 6909
CASP1 6827
RPS3A 6799
RPS19 6793
IRAK2 6748
PARP16 6479
PARP6 6437
CHMP3 6434
PIK3C3 6280
MGAT1 6226
MAVS 6159
UBB 6050
PCBP2 5838
RPS18 5767
RPS14 5716
FAU 5468
ITCH 5460
FKBP1A 5202
CHMP7 5154
RPS3 5150
ST3GAL2 5062
MOGS 4878
RPS26 4737
PARP10 4644
RPS9 4570
YWHAZ 4399
NFKB1 4199
VHL 4024
SP1 3987
RPS8 3907
RPS29 3760
PRKCSH 3701
SUMO1 3699
YWHAB 3519
PPIG 3411
SFN 3304
PARP9 3138
TRAF6 3111
PDPK1 2962
RPS2 2833
RPS27L 2825
RPS6 2795
NPM1 2784
TRAF3 2762
RPS15A 2682
CAV1 2544
RPS5 2510
HNRNPA1 2369
RIPK3 2334
RPS28 2309
RPS12 2017
RPS16 1909
CHMP2A 1810
ZCRB1 1778
RPS10 1666
PARP4 1404
PKLR 1395
ST6GALNAC2 1187
PSMC6 933
IRF3 487
UBA52 443
YWHAG 398
CHMP2B 392
GSK3B 32
EEF1A1 -41
SIKE1 -70
SMAD4 -282
RPS25 -336
UVRAG -379
TMPRSS2 -398
KPNA2 -687
RPS23 -1524
RPS27 -1537
RCAN3 -1588
CHMP4A -1606
GALNT1 -1632
UBE2I -1641
SERPINE1 -1675
RPS20 -1729
NLRP3 -1885
MAP1LC3B -1955
ST6GALNAC4 -1978
RPS21 -1987
RUNX1 -2356
ST3GAL1 -2546
GANAB -2564
PALS1 -2596
EP300 -2601
RPS24 -2603
GSK3A -3290
RB1 -3379
RPS11 -3542
TRIM25 -3605
BCL2L1 -3748
PARP14 -4700
ST6GAL1 -4946
STING1 -5114
CHMP6 -5445
YWHAH -5666
DDX5 -5832
RIPK1 -6575
RELA -6863
RPS13 -7476
RIGI -7493
ST3GAL4 -7605
IFIH1 -7734
YWHAQ -7802
BECN1 -8094
ST6GALNAC3 -8357
ST3GAL3 -8787
CHMP4B -8861
IKBKE -8990
TKFC -9057
PIK3R4 -9410
VCP -9523
CTSL -9733
SMAD3 -10027


REACTOME_SIGNALING_BY_INTERLEUKINS

REACTOME_SIGNALING_BY_INTERLEUKINS
800
set REACTOME_SIGNALING_BY_INTERLEUKINS
setSize 444
pANOVA 8.95e-05
s.dist 0.108
p.adjustANOVA 0.00432



Top enriched genes

Top 20 genes
GeneID Gene Rank
CCL4 10064
IL27 9996
CCL22 9755
CCL3 9737
CXCL10 9735
OSM 9697
MMP9 9692
PTPN7 9691
CCL5 9633
HAVCR2 9605
CCR1 9588
IL4 9579
PRTN3 9550
IL11 9505
CCR5 9440
PSMB3 9424
POMC 9118
RPS27A 9114
IL17RE 9108
NDN 9042

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CCL4 10064.0
IL27 9996.0
CCL22 9755.0
CCL3 9737.0
CXCL10 9735.0
OSM 9697.0
MMP9 9692.0
PTPN7 9691.0
CCL5 9633.0
HAVCR2 9605.0
CCR1 9588.0
IL4 9579.0
PRTN3 9550.0
IL11 9505.0
CCR5 9440.0
PSMB3 9424.0
POMC 9118.0
RPS27A 9114.0
IL17RE 9108.0
NDN 9042.0
RBX1 9024.0
CTF1 8986.0
NFKBIA 8956.0
IL32 8950.0
CANX 8922.0
IL21R 8890.0
SOX2 8872.0
H3C12 8871.0
ATF2 8853.0
HMGB1 8830.0
IL17RB 8760.0
LIF 8678.0
STX1A 8617.0
JUNB 8582.0
EBI3 8439.0
H3C6 8421.0
MAP3K8 8401.0
PSMD12 8359.0
PSMB2 8207.0
STAT4 8201.0
PELI3 8199.0
CISH 8156.0
LCK 8070.0
PSME1 8043.0
CRLF1 8026.0
IL18 8023.0
IL12RB1 8021.0
CD86 7990.0
PTPN18 7929.0
CXCL8 7859.0
BATF 7831.0
PIK3R1 7701.0
FPR1 7675.0
PSMB8 7596.0
GSTA2 7562.0
ITGB2 7537.0
PPIA 7469.0
MAP3K7 7394.0
TWIST1 7307.0
PSMB10 7164.0
TBK1 7103.0
IL18BP 7069.0
BTRC 7063.0
CTSG 7027.0
FASLG 7002.0
H3C3 6984.0
TIFA 6962.0
UBC 6955.0
STAT5A 6933.0
SOCS1 6894.0
CASP1 6827.0
IL7 6809.0
IRAK2 6748.0
FOXO1 6731.0
HCK 6679.0
PSMD7 6526.0
LCP1 6513.0
HIF1A 6510.0
BRWD1 6445.0
PIK3R3 6443.0
IL10 6438.0
CXCL1 6281.0
PSMC2 6236.0
SYK 6209.0
PSMB9 6207.0
NANOG 6067.0
UBB 6050.0
IL21 6006.0
CEBPD 5990.0
FGF2 5987.0
GSTO1 5947.0
IL18R1 5917.0
SOD2 5896.0
MAP2K3 5651.0
UBE2N 5648.0
DUSP4 5643.0
INPP5D 5633.0
PSMD5 5575.0
PTPN12 5562.0
H3C1 5532.0
PSMD9 5509.0
GRB2 5484.0
IL17RC 5474.0
HSPA8 5412.0
AIP 5411.0
IFNLR1 5383.0
CCR2 5337.0
CFL1 5319.0
PTPN11 5302.0
MAPKAPK2 5270.0
TGFB1 5261.0
IKBIP 5207.0
VIM 5195.0
MAPKAPK3 5139.0
IL1R2 5114.0
CRKL 5107.0
RPS6KA1 5025.0
CASP8 5020.0
PSMA7 4962.0
IL2RB 4942.0
ICAM1 4934.0
IRAK4 4917.0
IL6 4886.0
TXLNA 4863.0
RIPK2 4691.0
GAB2 4674.0
IL18RAP 4668.0
PSMA1 4589.0
TEC 4513.0
DUSP7 4498.0
LYN 4456.0
CNN2 4418.0
YWHAZ 4399.0
TNIP2 4388.0
SOD1 4334.0
TNFRSF1B 4297.0
IL1RAP 4208.0
NFKB1 4199.0
PPP2CA 4197.0
IL1B 4175.0
PSMD4 4162.0
HSP90AA1 4110.0
MYD88 4093.0
HNRNPA2B1 4066.0
CNTFR 4003.0
NKIRAS1 3968.0
H3C10 3945.0
PSMD3 3937.0
IL1RN 3915.0
IL23A 3906.0
VAMP2 3873.0
PSME2 3849.0
IL2RA 3813.0
NFKB2 3796.0
MEF2C 3788.0
MTAP 3634.0
IL31 3625.0
CCL2 3611.0
CUL1 3500.0
IL19 3363.0
CCL11 3325.0
PIK3CD 3305.0
TCP1 3270.0
CHUK 3247.0
PSMC5 3212.0
SOCS2 3203.0
IL23R 3112.0
TRAF6 3111.0
IL9 3088.0
PSMA5 2972.0
HMOX1 2848.0
PSMB4 2834.0
H3C7 2696.5
VAV1 2695.0
PTPN2 2693.0
MIF 2661.0
GSDMD 2652.0
PSME3 2641.0
H3C11 2569.0
ZEB1 2551.0
TNF 2537.0
IL15RA 2508.0
SOS2 2502.0
IL2 2429.0
PSMA2 2366.0
HGF 2308.0
IRF4 2261.0
IL16 2205.0
LAMA5 2177.0
BCL6 2176.0
IL1R1 2129.0
PITPNA 2115.0
HNRNPDL 2090.0
BCL2 2010.0
ARF1 2006.0
USP14 1980.0
PELI2 1887.0
PDCD4 1718.0
P4HB 1611.0
PTPN23 1579.0
SHC1 1418.0
NLRC5 1342.0
FBXW11 1250.0
STAT3 1244.0
MAPK7 1191.0
SOCS5 1125.0
RPS6KA5 1093.0
PIK3CA 1054.0
OSMR 1039.0
H3C4 958.0
PSMC6 933.0
CDKN1A 915.0
HNRNPF 914.0
IL1RL1 913.0
PSMA3 884.0
ALOX5 874.0
PAK2 871.0
CSF1R 870.0
IL20 741.0
OPRM1 738.0
TSLP 717.0
FCER2 690.0
MAPK10 682.0
CREB1 643.0
IL12B 609.0
SQSTM1 520.0
LGALS9 482.0
UBA52 443.0
IL4R 431.0
MAPK11 394.0
CBL 325.0
IL12A 185.0
PSMA6 176.0
MAP2K1 175.0
ALOX15 174.0
POU2F1 166.0
SDC1 63.0
HSP90B1 18.0
DUSP3 -83.0
MAP2K4 -123.0
PPP2R5D -128.0
UBE2V1 -140.0
S100A12 -190.0
CCL20 -195.0
STAT5B -204.0
JUN -329.0
PIK3CB -397.0
CAPZA1 -421.0
JAK1 -439.0
RHOU -511.0
TP53 -582.0
IL12RB2 -587.0
RPLP0 -676.0
IL6R -684.0
STX4 -766.0
MEF2A -874.0
IRAK3 -931.0
PSMD13 -945.0
USP18 -973.0
RAP1B -1066.0
LBP -1123.0
NKIRAS2 -1189.0
PSMB7 -1254.0
HSPA9 -1284.0
RAG2 -1305.0
PIM1 -1326.0
NFKBIB -1345.0
CASP3 -1454.0
MMP2 -1458.0
IL26 -1566.0
ATF1 -1648.0
STAT1 -1688.0
PPP2R1A -1758.0
MAPK8 -1806.0
MAP2K6 -1817.0
IL20RA -1887.0
PSMC1 -1911.0
MAPK1 -1913.0
IL36A -1990.0
RALA -1991.0
LMNB1 -2007.0
ITGAM -2038.0
FSCN1 -2064.0
LIFR -2164.0
IL36B -2199.0
PSMB1 -2266.0
PTPN4 -2275.0
SOCS3 -2291.0
JAK3 -2393.0
MCL1 -2490.0
MAPK14 -2491.0
TALDO1 -2527.0
APP -2592.0
S1PR1 -2633.0
YES1 -2729.0
RORC -2858.0
PSMD1 -2969.0
PTPN13 -2973.0
IL5 -3001.0
TAB1 -3013.0
PSMD14 -3064.0
MAP2K7 -3163.0
PSMB6 -3169.0
SNRPA1 -3256.0
CDC42 -3304.0
RAPGEF1 -3340.0
IRS1 -3351.0
PSMC4 -3386.0
FOS -3394.0
IL24 -3434.0
H3C2 -3460.0
IL17C -3489.0
VEGFA -3556.0
IL33 -3665.0
IFNG -3683.0
CD80 -3697.0
IL13 -3700.0
PSMB5 -3729.0
CD4 -3736.0
IL27RA -3739.0
BCL2L1 -3748.0
CCND1 -3790.0
PTK2B -3877.0
MMP3 -3882.0
PTPRZ1 -3884.0
ANXA2 -3903.0
PIK3R2 -3958.0
FYN -4031.0
SEM1 -4068.0
F13A1 -4100.0
ANXA1 -4205.0
COL1A2 -4209.0
TAB2 -4232.0
PSME4 -4304.0
SIGIRR -4316.0
GATA3 -4320.0
STX3 -4338.0
IL5RA -4450.0
MYC -4492.0
IL15 -4541.0
PTPN9 -4568.0
STXBP2 -4657.0
PTPN6 -4696.0
IL36RN -4729.0
MAP3K3 -4794.0
MUC1 -4902.0
CXCL2 -5016.0
IL1RL2 -5092.0
IL10RB -5103.0
PSMC3 -5134.0
PELI1 -5146.0
CD36 -5161.0
PSMD2 -5230.0
PSMD6 -5301.0
TNFRSF1A -5309.0
PSMA8 -5314.0
VRK3 -5352.0
IRS2 -5397.0
STAT2 -5418.0
IL31RA -5443.0
TOLLIP -5461.0
CRK -5529.0
RORA -5694.0
INPPL1 -5811.0
ITGAX -5891.0
IL34 -5911.0
IL17F -5914.0
CLCF1 -5974.0
PRKACA -6093.0
N4BP1 -6279.0
RPS6KA2 -6406.0
PSMD8 -6475.0
IKBKB -6487.0
CCL19 -6664.0
TRAF2 -6686.0
SNAP25 -6741.0
DUSP6 -6830.0
RELA -6863.0
H3C8 -7012.0
SERPINB2 -7059.0
S100B -7122.0
NOS2 -7243.0
SKP1 -7268.0
FOXO3 -7416.0
TYK2 -7457.0
MAPK3 -7509.0
MAPK9 -7519.0
JAK2 -7545.0
STAT6 -7607.0
SMARCA4 -7614.0
FN1 -7731.0
PTGS2 -7790.0
PSMD11 -7848.0
CSF2RB -8000.0
CSF3R -8012.0
IL20RB -8099.0
ITGB1 -8104.0
IL22RA2 -8133.0
IL1F10 -8165.0
IL10RA -8193.0
AKT1 -8221.0
IL22 -8300.0
SOS1 -8309.0
CNTF -8512.0
IL17RA -8567.0
IL7R -8581.0
IL37 -8624.0
VCAM1 -8629.0
IL22RA1 -8657.0
PTPN5 -8750.0
NOD1 -8854.0
PSMF1 -9271.0
PPP2CB -9369.0
IL25 -9426.0
LRRC14 -9509.0
OPRD1 -9588.0
ALPK1 -9651.0
IL17A -9947.0
PTPN14 -10014.0
SMAD3 -10027.0
LCN2 -10030.0
IL36G -10048.0
NLRX1 -10083.0
BIRC5 -10137.0
BLNK -10145.0
MMP1 -10157.0
PTAFR -10164.0
AGER -10180.0
PSMA4 -10354.0
CSF3 -10569.0
IFNL1 -10613.0
NOD2 -10711.0
CSF2 -10880.0
IL6ST -10899.0
CSF1 -10909.0
IL1A -10953.0
PPP2R1B -10955.0
PSMB11 -11028.0
IL11RA -11060.0
IFNL2 -11224.0
CA1 -11249.0
RAG1 -11282.0
SAA1 -11482.0
IL3 -11651.0


REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS
658
set REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS
setSize 66
pANOVA 9.73e-05
s.dist -0.277
p.adjustANOVA 0.00456



Top enriched genes

Top 20 genes
GeneID Gene Rank
ADAMTS4 -11483
NOTCH2 -11147
MUC5AC -11141
MUC4 -10962
MUCL1 -10610
B4GAT1 -10435
MUC13 -9922
LARGE1 -9617
ADAMTS10 -9574
ADAMTSL3 -9494
ADAMTSL1 -9210
ADAMTS2 -9155
ADAMTS5 -9024
ADAMTS16 -8966
THBS1 -8840
NOTCH1 -8791
MUC15 -8701
GALNT12 -8496
ADAMTS1 -8187
ADAMTS13 -7929

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ADAMTS4 -11483
NOTCH2 -11147
MUC5AC -11141
MUC4 -10962
MUCL1 -10610
B4GAT1 -10435
MUC13 -9922
LARGE1 -9617
ADAMTS10 -9574
ADAMTSL3 -9494
ADAMTSL1 -9210
ADAMTS2 -9155
ADAMTS5 -9024
ADAMTS16 -8966
THBS1 -8840
NOTCH1 -8791
MUC15 -8701
GALNT12 -8496
ADAMTS1 -8187
ADAMTS13 -7929
C1GALT1 -7850
THSD4 -7454
GALNT3 -7302
POMT2 -7104
DAG1 -6874
POMGNT1 -5950
MUC16 -5888
NOTCH3 -5441
ADAMTSL2 -5305
ADAMTS17 -5244
SSPOP -5236
ADAMTS3 -4974
MUC1 -4902
SPON1 -4878
ADAMTS15 -4523
THSD7A -4416
MUC6 -3988
THBS2 -3981
ADAMTS18 -3802
SBSPON -3751
SEMA5A -3678
POMT1 -3636
ADAMTS20 -3623
ADAMTS9 -2507
MUC20 -2462
SPON2 -1668
MUC7 -1332
MUC5B -1090
ADAMTS14 -1044
THSD7B -394
THSD1 -181
ADAMTS8 -160
SEMA5B -78
ADAMTS6 141
LFNG 610
ADAMTS12 1153
B3GLCT 2591
ADAMTS7 3122
NOTCH4 3419
ADAMTSL4 4035
MUC21 5274
ADAMTS19 6548
MUC17 6715
MUC12 7947
MUC3A 9506
ADAMTSL5 9941


REACTOME_M_PHASE

REACTOME_M_PHASE
1096
set REACTOME_M_PHASE
setSize 398
pANOVA 0.000103
s.dist 0.113
p.adjustANOVA 0.00456



Top enriched genes

Top 20 genes
GeneID Gene Rank
TUBB8 10067
H2BC6 9443
PSMB3 9424
CENPH 9394
POM121 9376
SGO1 9369
RPS27A 9114
TUBB2A 9007
TUBB2B 8961
HAUS1 8921
H3C12 8871
TUBA8 8859
TUBA4B 8804
H4C11 8752
H2BC5 8662
PLK1 8621
YWHAE 8616
NEDD1 8453
CDC23 8438
H3C6 8421

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TUBB8 10067.0
H2BC6 9443.0
PSMB3 9424.0
CENPH 9394.0
POM121 9376.0
SGO1 9369.0
RPS27A 9114.0
TUBB2A 9007.0
TUBB2B 8961.0
HAUS1 8921.0
H3C12 8871.0
TUBA8 8859.0
TUBA4B 8804.0
H4C11 8752.0
H2BC5 8662.0
PLK1 8621.0
YWHAE 8616.0
NEDD1 8453.0
CDC23 8438.0
H3C6 8421.0
CDC16 8398.0
AURKB 8361.0
PSMD12 8359.0
DYNC1LI1 8284.0
NUDC 8281.0
KPNB1 8280.0
KIF23 8240.0
PSMB2 8207.0
CENPS 8155.0
MZT2A 8145.0
CHMP4C 8102.0
PSME1 8043.0
H4C1 7956.0
ANAPC11 7883.0
NUP50 7809.0
NUP98 7806.0
XPO1 7719.0
CDCA8 7644.0
H3-3A 7620.0
HAUS8 7599.0
PSMB8 7596.0
RAE1 7570.0
H2BC14 7360.0
AHCTF1 7356.0
H2BC13 7347.0
WAPL 7310.0
PSMB10 7164.0
TAOK1 7156.0
BUB1B 7137.0
NME7 7095.0
CENPK 7007.0
H3C3 6984.0
H2BC3 6957.0
UBC 6955.0
H2AC4 6694.0
MAPRE1 6689.0
CCNB1 6675.0
H4C13 6661.0
SPAST 6582.0
PSMD7 6526.0
SMC4 6492.0
ITGB3BP 6440.0
ANAPC7 6436.0
CHMP3 6434.0
B9D2 6429.0
NSL1 6373.0
CLASP2 6327.0
H2AZ2 6310.0
PSMC2 6236.0
PSMB9 6207.0
UBB 6050.0
PLK4 5974.0
TUBB3 5910.0
NUP43 5862.0
CENPT 5778.0
RCC2 5667.0
TUBA4A 5624.0
CENPE 5620.0
NCAPD2 5607.0
PSMD5 5575.0
H3C1 5532.0
PSMD9 5509.0
CENPC 5500.0
PPP2R5B 5490.0
H4C3 5422.0
PPP1CC 5330.0
H4C9 5309.0
PCM1 5217.0
H3-3B 5160.0
CCNB2 5156.0
CHMP7 5154.0
NCAPH 5146.0
TUBB 5134.0
SGO2 5049.0
CSNK1E 4963.0
PSMA7 4962.0
BUB3 4888.0
NUP35 4736.0
ZW10 4716.0
CENPN 4680.0
ZWINT 4675.0
CEP41 4630.0
KMT5A 4591.0
PSMA1 4589.0
PDS5B 4580.0
PPP2R2A 4552.0
SIRT2 4482.0
TUBB4A 4471.0
RAD21 4470.0
KIF18A 4410.0
UBE2C 4308.0
LBR 4294.0
FBXO5 4225.0
PPP2CA 4197.0
CENPA 4186.0
CEP152 4176.0
PSMD4 4162.0
RAB1A 4117.0
DCTN2 4113.0
HSP90AA1 4110.0
CDCA5 4091.0
H2AC14 4031.0
RCC1 3988.0
H2BC12 3963.0
H3C10 3945.0
PSMD3 3937.0
MIS12 3918.0
MCPH1 3908.0
NCAPG2 3867.0
PSME2 3849.0
SUMO1 3699.0
UBE2D1 3621.0
NUP133 3541.0
CEP135 3507.0
TMPO 3353.0
PAFAH1B1 3321.0
HAUS6 3277.0
NCAPG 3244.0
RAB2A 3232.0
LPIN2 3218.0
PSMC5 3212.0
ANAPC4 3187.0
MASTL 2976.0
NUP85 2975.0
PSMA5 2972.0
CNEP1R1 2937.0
PPP2R5A 2860.0
PSMB4 2834.0
KNL1 2830.0
TNPO1 2826.0
CEP57 2787.0
NUP58 2746.0
H2BC9 2696.5
H3C7 2696.5
ALMS1 2692.0
PSME3 2641.0
NUP107 2575.0
H3C11 2569.0
CEP43 2527.0
CEP78 2466.0
GORASP2 2459.0
TUBB4B 2387.0
PSMA2 2366.0
TUBG1 2291.0
NUP155 2265.0
DYNLL1 2262.0
VRK2 2183.0
CDC26 2182.0
TUBG2 2122.0
TUBA3E 2102.0
TUBA1A 2084.0
PDS5A 2067.0
NDC1 1928.0
CHMP2A 1810.0
MZT1 1806.0
NEK9 1731.0
NUF2 1645.0
H2BC21 1628.0
RANBP2 1623.0
H4C4 1608.0
DSN1 1599.0
H4C16 1565.0
NDC80 1558.0
EML4 1493.0
LEMD3 1447.0
ANAPC5 1347.0
SET 1320.0
MZT2B 1262.0
PTTG1 1236.0
SDCCAG8 1129.0
SFI1 1018.0
CSNK2A1 972.0
H3C4 958.0
PSMC6 933.0
STAG1 896.0
PSMA3 884.0
H2BC17 820.0
H4C8 810.0
CEP250 763.0
NUP93 757.0
IST1 616.0
SEC13 551.0
POM121C 523.0
LPIN3 511.0
NUP153 497.0
RAB1B 474.0
UBA52 443.0
YWHAG 398.0
CHMP2B 392.0
NUP88 349.0
NUP210 310.0
PSMA6 176.0
NIPBL 100.0
H4C6 20.0
CEP290 -73.0
HAUS3 -111.0
PPP2R5D -128.0
PRKAR2B -144.0
PPP2R5C -164.0
SKA2 -206.0
KNTC1 -225.0
SPC25 -266.0
BUB1 -288.0
CEP76 -522.0
H2BC11 -531.0
SPDL1 -586.0
SPC24 -597.0
CLIP1 -605.0
ANKLE2 -623.0
ANAPC16 -645.0
DYNC1I2 -731.0
NUP188 -822.0
AKAP9 -836.0
PMF1 -856.0
MAD2L1 -889.0
PSMD13 -945.0
TPR -967.0
NUP62 -1072.0
SKA1 -1105.0
NDE1 -1155.0
PSMB7 -1254.0
H2BC15 -1269.0
ANAPC1 -1288.0
CSNK2B -1315.0
CC2D1B -1512.0
CTDNEP1 -1517.0
RPS27 -1537.0
CHMP4A -1606.0
TUBGCP3 -1609.0
CKAP5 -1621.0
UBE2I -1641.0
SEH1L -1661.0
LMNA -1752.0
PPP2R1A -1758.0
NUP214 -1861.0
PSMC1 -1911.0
MAPK1 -1913.0
TUBA1B -1967.0
LMNB1 -2007.0
CEP72 -2050.0
CEP131 -2052.0
TUBGCP5 -2058.0
BLZF1 -2062.0
NUP160 -2107.0
PSMB1 -2266.0
CENPJ -2333.0
CEP63 -2398.0
UBE2E1 -2415.0
CCP110 -2418.0
TUBGCP6 -2449.0
CLASP1 -2458.0
ANAPC10 -2472.0
H2BC4 -2556.0
KIF2A -2584.0
NCAPH2 -2589.0
H2AC20 -2685.0
AAAS -2886.0
NEK2 -2930.0
PSMD1 -2969.0
PSMD14 -3064.0
PRKCB -3067.0
KIF20A -3085.0
NUP205 -3107.0
PSMB6 -3169.0
GOLGA2 -3282.0
RB1 -3379.0
PSMC4 -3386.0
H3C2 -3460.0
CDC27 -3640.0
VPS4A -3688.0
CENPF -3728.0
PSMB5 -3729.0
H2AC6 -3847.0
DYNC1I1 -3848.0
CDC20 -3888.0
H2AC7 -3916.5
H2BC7 -3916.5
NUP54 -3926.0
SEM1 -4068.0
HAUS4 -4107.0
ENSA -4147.0
ODF2 -4227.0
PSME4 -4304.0
ESPL1 -4329.0
RAN -4355.0
CNTRL -4420.0
NDEL1 -4470.0
GORASP1 -4556.0
TUBB6 -4579.0
CEP70 -4671.0
CENPL -4733.0
ARPP19 -4770.0
NUP42 -4844.0
CENPM -4846.0
H4C12 -4954.0
SMC3 -5110.0
NEK7 -5120.0
PSMC3 -5134.0
DYNC1LI2 -5155.0
NINL -5183.0
PSMD2 -5230.0
PSMD6 -5301.0
BANF1 -5310.0
PSMA8 -5314.0
CHMP6 -5445.0
H2BC1 -5630.0
VRK1 -5641.0
PCNT -5740.0
UBE2S -5853.0
CEP192 -5906.0
CDK1 -5988.0
H2AZ1 -5992.0
NEK6 -5993.0
DCTN1 -6015.0
HAUS2 -6028.0
PRKACA -6093.0
TUBA3C -6096.0
PPP2R5E -6139.0
H2AC18 -6150.5
H2AC19 -6150.5
CDK5RAP2 -6196.0
H2BC8 -6266.0
CENPU -6267.0
SSNA1 -6376.0
ACTR1A -6470.0
PSMD8 -6475.0
NUP37 -6563.0
CENPQ -6703.0
TUBA1C -6828.0
CEP164 -6934.0
HAUS5 -6972.0
H3C8 -7012.0
TUBAL3 -7065.0
TUBGCP4 -7076.0
ANAPC2 -7140.0
H2AC8 -7163.0
H2AJ -7223.0
ANAPC15 -7315.0
KIF2C -7340.0
LPIN1 -7372.0
MAU2 -7433.0
CENPO -7459.0
MAPK3 -7509.0
MAD1L1 -7623.0
PSMD11 -7848.0
USO1 -7993.0
TUBGCP2 -8171.0
PPP2R2D -8231.0
PRKCA -8381.0
H4C5 -8476.0
CENPP -8633.0
H2BC10 -8762.0
CSNK1D -8860.0
CHMP4B -8861.0
H3-4 -8982.0
CSNK2A2 -9111.0
NCAPD3 -9146.0
LEMD2 -9150.0
SMC2 -9212.0
PSMF1 -9271.0
NUMA1 -9337.0
INCENP -9361.0
PPP2CB -9369.0
H2AX -9465.0
ZWILCH -9723.0
TUBB1 -9794.0
H4C2 -9982.0
DCTN3 -10034.0
BIRC5 -10137.0
RANGAP1 -10242.0
H2BC26 -10312.0
DYNLL2 -10341.0
PSMA4 -10354.0
DYNC1H1 -10369.0
KIF2B -10676.0
PPP2R1B -10955.0
PSMB11 -11028.0
TUBA3D -11433.0


REACTOME_MITOCHONDRIAL_TRANSLATION

REACTOME_MITOCHONDRIAL_TRANSLATION
874
set REACTOME_MITOCHONDRIAL_TRANSLATION
setSize 93
pANOVA 0.000103
s.dist 0.233
p.adjustANOVA 0.00456



Top enriched genes

Top 20 genes
GeneID Gene Rank
CHCHD1 9677
TUFM 9492
MRPL52 9417
MTIF2 9272
MRPL16 9251
ERAL1 9250
MRPL53 8876
MTFMT 8829
MRPL33 8749
MRPL36 8197
MRPL44 7826
TSFM 7799
MRPS18C 7742
MRPS24 7723
MRPS18B 7627
MRPL9 7515
MRPS26 7497
MRPS15 7293
MRPL14 7082
MRPL28 6801

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CHCHD1 9677
TUFM 9492
MRPL52 9417
MTIF2 9272
MRPL16 9251
ERAL1 9250
MRPL53 8876
MTFMT 8829
MRPL33 8749
MRPL36 8197
MRPL44 7826
TSFM 7799
MRPS18C 7742
MRPS24 7723
MRPS18B 7627
MRPL9 7515
MRPS26 7497
MRPS15 7293
MRPL14 7082
MRPL28 6801
MRPL20 6297
MRPS7 6220
MRPL15 6204
MRPL10 6186
MRPS14 6107
MRPL42 6104
GADD45GIP1 5970
MRPL48 5684
MRPL40 5324
MRPS18A 5050
MRPL32 4986
MRPS10 4654
MRPL51 4469
MRPS11 4357
MRPL41 4224
MRPL17 4187
MRPL57 4030
MRPL4 3824
MRPL54 3583
MRPL13 3577
MRPL35 3407
MRPS21 3159
MRPS12 3133
MRPS23 3070
PTCD3 2694
MRPL24 2064
MTIF3 2050
MRPL38 2004
MRPL49 2002
MRRF 1982
GFM1 1976
MRPL34 1930
AURKAIP1 1375
MRPL19 1264
MRPS31 1092
MRPS9 1072
MRPL50 919
MRPL18 793
MRPL55 550
MRPL45 111
MRPL2 76
MRPS22 -694
MRPL30 -1128
GFM2 -1265
MRPL1 -1391
MRPL39 -1462
MRPL37 -1538
MRPL22 -2488
MRPS17 -2619
MTRF1L -2916
MRPL3 -3083
MRPS35 -3279
MRPS25 -3332
MRPS2 -3374
MRPL46 -3392
OXA1L -3527
MRPS27 -3938
MRPS34 -4035
MRPL21 -4352
MRPS16 -4721
MRPL12 -4817
MRPS28 -5027
DAP3 -5039
MRPS30 -5059
MRPS33 -6109
MRPS6 -7711
MRPL23 -8687
MRPL58 -8802
MRPL43 -8872
MRPL11 -9327
MRPL47 -9719
MRPL27 -9786
MRPS5 -10151


REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX
115
set REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX
setSize 134
pANOVA 0.000182
s.dist -0.187
p.adjustANOVA 0.00786



Top enriched genes

Top 20 genes
GeneID Gene Rank
PRSS1 -11913
CAPNS2 -11745
ADAMTS4 -11483
KLKB1 -11408
CAPN14 -11014
FURIN -10856
CTRB1 -10698
CTRB2 -10673
MMP1 -10157
CAPN13 -10091
LAMB3 -9902
COL6A3 -9785
MMP7 -9748
CTSL -9733
MMP16 -9663
SCUBE1 -9578
COL6A1 -9490
BMP1 -9339
CAPN15 -9090
COL5A1 -9067

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PRSS1 -11913
CAPNS2 -11745
ADAMTS4 -11483
KLKB1 -11408
CAPN14 -11014
FURIN -10856
CTRB1 -10698
CTRB2 -10673
MMP1 -10157
CAPN13 -10091
LAMB3 -9902
COL6A3 -9785
MMP7 -9748
CTSL -9733
MMP16 -9663
SCUBE1 -9578
COL6A1 -9490
BMP1 -9339
CAPN15 -9090
COL5A1 -9067
ADAMTS5 -9024
CAPN5 -8996
ADAMTS16 -8966
ACAN -8954
MMP19 -8887
HTRA1 -8834
COL23A1 -8742
HSPG2 -8681
CAPN2 -8422
COL4A2 -8323
COL13A1 -8286
DCN -8206
ADAMTS1 -8187
COL17A1 -8125
COL15A1 -8068
FN1 -7731
ADAM9 -7597
SCUBE3 -7403
CAPN3 -7354
MMP14 -7254
ADAM8 -6806
CAPN1 -6715
COL14A1 -6643
COL25A1 -6623
ADAM17 -6592
CTSD -6584
MMP17 -6578
A2M -6394
COL4A4 -6284
COL4A1 -5804
TLL1 -5399
COL5A2 -5327
COL3A1 -5287
MMP13 -5248
SPOCK3 -4949
COL18A1 -4835
CAPN10 -4524
FBN1 -4474
ADAM15 -4291
FBN2 -4245
COL1A2 -4209
LAMC1 -4096
CAPN9 -3918
MMP3 -3882
MMP8 -3825
ADAMTS18 -3802
CAPNS1 -3618
COL9A3 -3614
CDH1 -3562
MMP24 -3515
COL2A1 -3364
ELN -3324
CD44 -3231
PHYKPL -2878
ADAMTS9 -2507
COL6A2 -2375
COL4A3 -2310
LAMA3 -2137
LAMC2 -1953
FBN3 -1480
MMP2 -1458
CASP3 -1454
COL10A1 -1363
MMP10 -1163
CTSB -1115
OPTC -1002
COL8A2 -767
COL6A6 -551
CAPN11 -307
COL11A2 -281
ADAMTS8 -160
CAPN8 -56
TIMP2 488
NCSTN 536
CMA1 543
ELANE 589
CAST 699
MMP20 703
LAMB1 823
COL9A2 851
MMP15 877
CAPN7 979
TLL2 1304
BSG 1488
PSEN1 1710
MMP11 1827
KLK7 1988
LAMA5 2177
COL5A3 2328
NID1 2952
COL16A1 3173
ADAM10 3174
COL12A1 3663
COL6A5 3722
COL7A1 3921
COL9A1 4008
COL19A1 4752
COL1A1 4826
MMP12 4938
COL8A1 5110
CTSK 5117
COL26A1 5331
PLG 5409
CTSS 5489
MMP25 5543
TMPRSS6 6300
BCAN 6940
CTSG 7027
SPP1 7487
KLK2 7518
COL11A1 7966
CAPN12 8163
CTSV 8822
MMP9 9692


REACTOME_SARS_COV_1_ACTIVATES_MODULATES_INNATE_IMMUNE_RESPONSES

REACTOME_SARS_COV_1_ACTIVATES_MODULATES_INNATE_IMMUNE_RESPONSES
1551
set REACTOME_SARS_COV_1_ACTIVATES_MODULATES_INNATE_IMMUNE_RESPONSES
setSize 39
pANOVA 0.000209
s.dist 0.343
p.adjustANOVA 0.00867



Top enriched genes

Top 20 genes
GeneID Gene Rank
BST2 9971
RPS27A 9114
NFKBIA 8956
PYCARD 8915
PPIB 8785
KPNB1 8280
SFTPD 8215
TOMM70 8204
PPIH 8061
NMI 7549
PPIA 7469
TBK1 7103
UBC 6955
CASP1 6827
IRAK2 6748
MAVS 6159
UBB 6050
PCBP2 5838
ITCH 5460
FKBP1A 5202

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
BST2 9971
RPS27A 9114
NFKBIA 8956
PYCARD 8915
PPIB 8785
KPNB1 8280
SFTPD 8215
TOMM70 8204
PPIH 8061
NMI 7549
PPIA 7469
TBK1 7103
UBC 6955
CASP1 6827
IRAK2 6748
MAVS 6159
UBB 6050
PCBP2 5838
ITCH 5460
FKBP1A 5202
NFKB1 4199
PPIG 3411
TRAF6 3111
TRAF3 2762
RIPK3 2334
IRF3 487
UBA52 443
SIKE1 -70
KPNA2 -687
RCAN3 -1588
NLRP3 -1885
RUNX1 -2356
TRIM25 -3605
STING1 -5114
RELA -6863
RIGI -7493
IFIH1 -7734
IKBKE -8990
TKFC -9057


REACTOME_SARS_COV_2_INFECTION

REACTOME_SARS_COV_2_INFECTION
1553
set REACTOME_SARS_COV_2_INFECTION
setSize 281
pANOVA 0.000211
s.dist 0.128
p.adjustANOVA 0.00867



Top enriched genes

Top 20 genes
GeneID Gene Rank
IFNB1 10040.0
IFNA7 10007.0
IFNA8 9963.0
IFNA1 9879.0
IFNA2 9553.0
TUFM 9492.0
POM121 9376.0
IFNA5 9289.0
VPS18 9203.0
RPS27A 9114.0
SMN1 9067.5
SMN2 9067.5
PARP8 8931.0
CANX 8922.0
SDC3 8909.0
HLA-G 8671.0
YWHAE 8616.0
ZDHHC5 8564.0
GEMIN6 8546.0
SNRPD1 8497.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
IFNB1 10040.0
IFNA7 10007.0
IFNA8 9963.0
IFNA1 9879.0
IFNA2 9553.0
TUFM 9492.0
POM121 9376.0
IFNA5 9289.0
VPS18 9203.0
RPS27A 9114.0
SMN1 9067.5
SMN2 9067.5
PARP8 8931.0
CANX 8922.0
SDC3 8909.0
HLA-G 8671.0
YWHAE 8616.0
ZDHHC5 8564.0
GEMIN6 8546.0
SNRPD1 8497.0
NLRP12 8385.0
SFTPD 8215.0
TOMM70 8204.0
MGAT4A 8114.0
CHMP4C 8102.0
RPSA 7996.0
NUP50 7809.0
NUP98 7806.0
RPS7 7771.0
SNRPF 7761.0
RAE1 7570.0
GEMIN2 7468.0
HSP90AB1 7466.0
RPN1 7418.0
MAP3K7 7394.0
IRF7 7249.0
TBK1 7103.0
SRPK1 7045.0
UBC 6955.0
RPS15 6909.0
B2M 6839.0
RPS3A 6799.0
RPS19 6793.0
IRAK2 6748.0
PARP16 6479.0
PARP6 6437.0
CHMP3 6434.0
PIK3C3 6280.0
GOLGA7 6261.0
MGAT1 6226.0
MAVS 6159.0
HLA-B 6143.0
STT3A 6101.0
UBB 6050.0
GPC2 5925.0
NUP43 5862.0
G3BP1 5858.0
RPS18 5767.0
AGRN 5753.0
RPS14 5716.0
UBE2N 5648.0
IL17RC 5474.0
FAU 5468.0
HLA-A 5457.0
GEMIN5 5394.0
PTPN11 5302.0
HLA-C 5275.0
CHMP7 5154.0
RPS3 5150.0
DDX20 5122.0
ST3GAL2 5062.0
MOGS 4878.0
G3BP2 4828.0
HLA-F 4775.0
RPS26 4737.0
NUP35 4736.0
RIPK2 4691.0
PARP10 4644.0
CNBP 4640.0
RPS9 4570.0
GEMIN7 4441.0
YWHAZ 4399.0
SNRPD2 4363.0
HSP90AA1 4110.0
MASP1 4027.0
VHL 4024.0
TLR2 3956.0
TRIM4 3944.0
RPS8 3907.0
MGAT4C 3781.0
RPS29 3760.0
PRKCSH 3701.0
SUMO1 3699.0
IFNAR1 3590.0
NUP133 3541.0
YWHAB 3519.0
ISCU 3349.0
SFN 3304.0
CHUK 3247.0
PARP9 3138.0
ZDHHC11 3116.0
TRAF6 3111.0
CSNK1A1 3016.0
NUP85 2975.0
PDPK1 2962.0
SEC23A 2953.0
RPS2 2833.0
RPS27L 2825.0
RPS6 2795.0
TRAF3 2762.0
NUP58 2746.0
RPS15A 2682.0
NUP107 2575.0
CAV1 2544.0
RPS5 2510.0
ANO10 2310.0
RPS28 2309.0
TLR1 2278.0
NUP155 2265.0
SDC4 2079.0
RPS12 2017.0
NDC1 1928.0
RPS16 1909.0
CHMP2A 1810.0
ZCRB1 1778.0
HLA-E 1709.0
RPS10 1666.0
HAVCR1 1643.0
RANBP2 1623.0
VPS45 1620.0
PARP4 1404.0
AKT2 1356.0
ST6GALNAC2 1187.0
SNRPD3 1055.0
NRP1 1023.0
RPN2 867.0
MGAT2 783.5
NUP93 757.0
SAR1B 608.0
SEC13 551.0
POM121C 523.0
NUP153 497.0
IRF3 487.0
ATG14 455.0
UBA52 443.0
YWHAG 398.0
CHMP2B 392.0
NUP88 349.0
NUP210 310.0
SDC1 63.0
GSK3B 32.0
DAD1 -28.0
SIKE1 -70.0
UBE2V1 -140.0
IFNA16 -210.0
RPS25 -336.0
UVRAG -379.0
TMPRSS2 -398.0
JAK1 -439.0
SRPK2 -465.0
ISG15 -518.0
SNRPG -533.0
SEC24A -568.0
KPNA2 -687.0
ANO6 -807.0
NUP188 -822.0
SEC24D -884.0
IFNA13 -893.0
DDOST -959.0
TPR -967.0
GJA1 -1027.0
NUP62 -1072.0
ANO8 -1312.0
RPS23 -1524.0
RPS27 -1537.0
PRMT1 -1587.0
CHMP4A -1606.0
GALNT1 -1632.0
UBE2I -1641.0
EDEM2 -1647.0
SEH1L -1661.0
STAT1 -1688.0
SNRPE -1701.0
RPS20 -1729.0
NUP214 -1861.0
NLRP3 -1885.0
MAP1LC3B -1955.0
ST6GALNAC4 -1978.0
RPS21 -1987.0
NUP160 -2107.0
MGAT4B -2197.0
ZDHHC2 -2410.0
VPS16 -2539.0
ST3GAL1 -2546.0
GANAB -2564.0
PALS1 -2596.0
RPS24 -2603.0
TJP1 -2787.0
AAAS -2886.0
ZDHHC20 -2998.0
TAB1 -3013.0
ANO3 -3017.0
GPC5 -3045.0
NUP205 -3107.0
VPS39 -3136.0
GSK3A -3290.0
RB1 -3379.0
SNRPB -3393.0
RPS11 -3542.0
TRIM25 -3605.0
GEMIN4 -3673.0
NUP54 -3926.0
ANO5 -3927.0
PATJ -4042.0
ANO4 -4045.0
TAB2 -4232.0
GPC1 -4354.0
SEC24C -4421.0
IFNA14 -4478.0
IFNAR2 -4571.0
SEC24B -4574.0
VPS33B -4652.0
PTPN6 -4696.0
PARP14 -4700.0
IFNA6 -4707.0
ZDHHC3 -4761.0
CRB3 -4836.0
NUP42 -4844.0
ST6GAL1 -4946.0
STING1 -5114.0
ANO2 -5284.0
TUSC3 -5343.0
MASP2 -5355.0
STAT2 -5418.0
CHMP6 -5445.0
ZDHHC8 -5647.0
YWHAH -5666.0
CREBBP -5814.0
DDX5 -5832.0
IL17F -5914.0
MGAT5 -6318.0
VPS11 -6349.0
VPS41 -6471.0
IKBKB -6487.0
NUP37 -6563.0
MAN1B1 -6609.0
RNF135 -6780.0
GPC6 -6909.0
AKT3 -7041.0
TYK2 -7457.0
RPS13 -7476.0
RIGI -7493.0
SDC2 -7524.0
ST3GAL4 -7605.0
IFIH1 -7734.0
YWHAQ -7802.0
ANO9 -7932.0
BECN1 -8094.0
LARP1 -8096.0
VPS33A -8110.0
AKT1 -8221.0
ST6GALNAC3 -8357.0
IL17RA -8567.0
MAN2A1 -8603.0
HSPG2 -8681.0
ST3GAL3 -8787.0
NOD1 -8854.0
CHMP4B -8861.0
FUT8 -8879.0
ANO1 -8915.0
IKBKE -8990.0
TKFC -9057.0
PIK3R4 -9410.0
VCP -9523.0
IFNA21 -9675.0
CTSL -9733.0
IL17A -9947.0
ANO7 -10504.0
NOD2 -10711.0
FURIN -10856.0
MBL2 -11624.0


REACTOME_DNA_REPLICATION_PRE_INITIATION

REACTOME_DNA_REPLICATION_PRE_INITIATION
1101
set REACTOME_DNA_REPLICATION_PRE_INITIATION
setSize 150
pANOVA 0.000257
s.dist 0.173
p.adjustANOVA 0.0102



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC6 9443
PSMB3 9424
RPS27A 9114
H3C12 8871
H4C11 8752
H2BC5 8662
CDC23 8438
H3C6 8421
CDC16 8398
PSMD12 8359
GMNN 8324
KPNB1 8280
PSMB2 8207
PSME1 8043
H4C1 7956
ANAPC11 7883
PRIM2 7731
MCM5 7689
H3-3A 7620
PSMB8 7596

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC6 9443.0
PSMB3 9424.0
RPS27A 9114.0
H3C12 8871.0
H4C11 8752.0
H2BC5 8662.0
CDC23 8438.0
H3C6 8421.0
CDC16 8398.0
PSMD12 8359.0
GMNN 8324.0
KPNB1 8280.0
PSMB2 8207.0
PSME1 8043.0
H4C1 7956.0
ANAPC11 7883.0
PRIM2 7731.0
MCM5 7689.0
H3-3A 7620.0
PSMB8 7596.0
RPA2 7507.0
H2BC14 7360.0
H2BC13 7347.0
POLE3 7203.0
PSMB10 7164.0
H3C3 6984.0
H2BC3 6957.0
UBC 6955.0
DBF4 6952.0
ORC5 6733.0
H2AC4 6694.0
H4C13 6661.0
PSMD7 6526.0
ANAPC7 6436.0
H2AZ2 6310.0
PSMC2 6236.0
PSMB9 6207.0
UBB 6050.0
ORC2 5616.0
POLE4 5579.0
PSMD5 5575.0
POLE2 5549.0
H3C1 5532.0
PSMD9 5509.0
CDK2 5496.0
H4C3 5422.0
H4C9 5309.0
CDT1 5229.0
H3-3B 5160.0
PSMA7 4962.0
RPA1 4760.0
PSMA1 4589.0
MCM3 4473.0
UBE2C 4308.0
PSMD4 4162.0
H2AC14 4031.0
H2BC12 3963.0
H3C10 3945.0
PSMD3 3937.0
PSME2 3849.0
UBE2D1 3621.0
CDC6 3474.0
PSMC5 3212.0
ANAPC4 3187.0
PSMA5 2972.0
PSMB4 2834.0
H2BC9 2696.5
H3C7 2696.5
PSME3 2641.0
H3C11 2569.0
PRIM1 2456.0
POLA2 2389.0
PSMA2 2366.0
CDC26 2182.0
MCM2 1927.0
MCM8 1757.0
H2BC21 1628.0
H4C4 1608.0
H4C16 1565.0
ANAPC5 1347.0
H3C4 958.0
PSMC6 933.0
PSMA3 884.0
H2BC17 820.0
H4C8 810.0
UBA52 443.0
PSMA6 176.0
H4C6 20.0
KPNA6 -129.0
H2BC11 -531.0
ANAPC16 -645.0
PSMD13 -945.0
PSMB7 -1254.0
H2BC15 -1269.0
ANAPC1 -1288.0
ORC4 -1798.0
PSMC1 -1911.0
PSMB1 -2266.0
UBE2E1 -2415.0
ANAPC10 -2472.0
MCM10 -2500.0
H2BC4 -2556.0
H2AC20 -2685.0
ORC3 -2778.0
PSMD1 -2969.0
PSMD14 -3064.0
PSMB6 -3169.0
MCM6 -3273.0
PSMC4 -3386.0
H3C2 -3460.0
MCM4 -3606.0
CDC27 -3640.0
PSMB5 -3729.0
H2AC6 -3847.0
CDC7 -3856.0
H2AC7 -3916.5
H2BC7 -3916.5
SEM1 -4068.0
H4C12 -4954.0
PSMC3 -5134.0
PSMD2 -5230.0
PSMD6 -5301.0
RPA3 -5613.0
H2BC1 -5630.0
POLE -5717.0
UBE2S -5853.0
FZR1 -5912.0
CDC45 -5943.0
H2AZ1 -5992.0
H2AC18 -6150.5
H2AC19 -6150.5
H2BC8 -6266.0
PSMD8 -6475.0
KPNA1 -6645.0
ORC6 -6767.0
H3C8 -7012.0
ANAPC2 -7140.0
H2AC8 -7163.0
H2AJ -7223.0
ANAPC15 -7315.0
PSMD11 -7848.0
ORC1 -8202.0
H4C5 -8476.0
H2BC10 -8762.0
PSMF1 -9271.0
MCM7 -9353.0
H2AX -9465.0
H4C2 -9982.0
H2BC26 -10312.0
PSMA4 -10354.0


REACTOME_SEPARATION_OF_SISTER_CHROMATIDS

REACTOME_SEPARATION_OF_SISTER_CHROMATIDS
492
set REACTOME_SEPARATION_OF_SISTER_CHROMATIDS
setSize 184
pANOVA 0.000261
s.dist 0.156
p.adjustANOVA 0.0102



Top enriched genes

Top 20 genes
GeneID Gene Rank
TUBB8 10067
PSMB3 9424
CENPH 9394
SGO1 9369
RPS27A 9114
TUBB2A 9007
TUBB2B 8961
TUBA8 8859
TUBA4B 8804
PLK1 8621
CDC23 8438
CDC16 8398
AURKB 8361
PSMD12 8359
DYNC1LI1 8284
NUDC 8281
PSMB2 8207
CENPS 8155
PSME1 8043
ANAPC11 7883

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TUBB8 10067
PSMB3 9424
CENPH 9394
SGO1 9369
RPS27A 9114
TUBB2A 9007
TUBB2B 8961
TUBA8 8859
TUBA4B 8804
PLK1 8621
CDC23 8438
CDC16 8398
AURKB 8361
PSMD12 8359
DYNC1LI1 8284
NUDC 8281
PSMB2 8207
CENPS 8155
PSME1 8043
ANAPC11 7883
NUP98 7806
XPO1 7719
CDCA8 7644
PSMB8 7596
AHCTF1 7356
WAPL 7310
PSMB10 7164
TAOK1 7156
BUB1B 7137
CENPK 7007
UBC 6955
MAPRE1 6689
PSMD7 6526
ITGB3BP 6440
ANAPC7 6436
B9D2 6429
NSL1 6373
CLASP2 6327
PSMC2 6236
PSMB9 6207
UBB 6050
TUBB3 5910
NUP43 5862
CENPT 5778
RCC2 5667
TUBA4A 5624
CENPE 5620
PSMD5 5575
PSMD9 5509
CENPC 5500
PPP2R5B 5490
PPP1CC 5330
SGO2 5049
PSMA7 4962
BUB3 4888
ZW10 4716
CENPN 4680
ZWINT 4675
PSMA1 4589
PDS5B 4580
TUBB4A 4471
RAD21 4470
KIF18A 4410
UBE2C 4308
PPP2CA 4197
CENPA 4186
PSMD4 4162
CDCA5 4091
PSMD3 3937
MIS12 3918
PSME2 3849
UBE2D1 3621
NUP133 3541
PAFAH1B1 3321
PSMC5 3212
ANAPC4 3187
NUP85 2975
PSMA5 2972
PPP2R5A 2860
PSMB4 2834
KNL1 2830
PSME3 2641
NUP107 2575
TUBB4B 2387
PSMA2 2366
DYNLL1 2262
CDC26 2182
TUBA3E 2102
TUBA1A 2084
PDS5A 2067
NUF2 1645
RANBP2 1623
DSN1 1599
NDC80 1558
ANAPC5 1347
PTTG1 1236
PSMC6 933
STAG1 896
PSMA3 884
SEC13 551
UBA52 443
PSMA6 176
PPP2R5D -128
PPP2R5C -164
SKA2 -206
KNTC1 -225
SPC25 -266
BUB1 -288
SPDL1 -586
SPC24 -597
CLIP1 -605
ANAPC16 -645
DYNC1I2 -731
PMF1 -856
MAD2L1 -889
PSMD13 -945
SKA1 -1105
NDE1 -1155
PSMB7 -1254
ANAPC1 -1288
RPS27 -1537
CKAP5 -1621
SEH1L -1661
PPP2R1A -1758
PSMC1 -1911
TUBA1B -1967
NUP160 -2107
PSMB1 -2266
UBE2E1 -2415
CLASP1 -2458
ANAPC10 -2472
KIF2A -2584
PSMD1 -2969
PSMD14 -3064
PSMB6 -3169
PSMC4 -3386
CDC27 -3640
CENPF -3728
PSMB5 -3729
DYNC1I1 -3848
CDC20 -3888
SEM1 -4068
PSME4 -4304
ESPL1 -4329
NDEL1 -4470
TUBB6 -4579
CENPL -4733
CENPM -4846
SMC3 -5110
PSMC3 -5134
DYNC1LI2 -5155
PSMD2 -5230
PSMD6 -5301
PSMA8 -5314
UBE2S -5853
TUBA3C -6096
PPP2R5E -6139
CENPU -6267
PSMD8 -6475
NUP37 -6563
CENPQ -6703
TUBA1C -6828
TUBAL3 -7065
ANAPC2 -7140
ANAPC15 -7315
KIF2C -7340
CENPO -7459
MAD1L1 -7623
PSMD11 -7848
CENPP -8633
PSMF1 -9271
INCENP -9361
PPP2CB -9369
ZWILCH -9723
TUBB1 -9794
BIRC5 -10137
RANGAP1 -10242
DYNLL2 -10341
PSMA4 -10354
DYNC1H1 -10369
KIF2B -10676
PPP2R1B -10955
PSMB11 -11028
TUBA3D -11433


REACTOME_SARS_COV_INFECTIONS

REACTOME_SARS_COV_INFECTIONS
1541
set REACTOME_SARS_COV_INFECTIONS
setSize 392
pANOVA 0.000278
s.dist 0.107
p.adjustANOVA 0.0106



Top enriched genes

Top 20 genes
GeneID Gene Rank
IFNB1 10040.0
IFNA7 10007.0
BST2 9971.0
IFNA8 9963.0
IFNA1 9879.0
IFNA2 9553.0
TUFM 9492.0
POM121 9376.0
IFNA5 9289.0
VPS18 9203.0
RPS27A 9114.0
SMN1 9067.5
SMN2 9067.5
RBX1 9024.0
NFKBIA 8956.0
PARP8 8931.0
CANX 8922.0
PYCARD 8915.0
SDC3 8909.0
PPIB 8785.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
IFNB1 10040.0
IFNA7 10007.0
BST2 9971.0
IFNA8 9963.0
IFNA1 9879.0
IFNA2 9553.0
TUFM 9492.0
POM121 9376.0
IFNA5 9289.0
VPS18 9203.0
RPS27A 9114.0
SMN1 9067.5
SMN2 9067.5
RBX1 9024.0
NFKBIA 8956.0
PARP8 8931.0
CANX 8922.0
PYCARD 8915.0
SDC3 8909.0
PPIB 8785.0
HLA-G 8671.0
CD79A 8650.0
YWHAE 8616.0
ZDHHC5 8564.0
GEMIN6 8546.0
SNRPD1 8497.0
NLRP12 8385.0
KPNB1 8280.0
SFTPD 8215.0
TOMM70 8204.0
ITGA4 8187.0
MGAT4A 8114.0
CHMP4C 8102.0
PPIH 8061.0
RPSA 7996.0
MTA2 7912.0
NUP50 7809.0
NUP98 7806.0
RPS7 7771.0
SNRPF 7761.0
RAE1 7570.0
NMI 7549.0
NCK1 7516.0
PPIA 7469.0
GEMIN2 7468.0
HSP90AB1 7466.0
RPN1 7418.0
MAP3K7 7394.0
IRF7 7249.0
TBK1 7103.0
SRPK1 7045.0
UBC 6955.0
RPS15 6909.0
B2M 6839.0
CASP1 6827.0
RPS3A 6799.0
RPS19 6793.0
IRAK2 6748.0
PARP16 6479.0
FKBP4 6470.0
PARP6 6437.0
CHMP3 6434.0
PIK3C3 6280.0
GOLGA7 6261.0
MGAT1 6226.0
SYK 6209.0
MAVS 6159.0
HLA-B 6143.0
STT3A 6101.0
IFNGR1 6086.0
UBB 6050.0
SAP30 6035.0
GPC2 5925.0
NUP43 5862.0
G3BP1 5858.0
PCBP2 5838.0
RPS18 5767.0
AGRN 5753.0
RPS14 5716.0
UBE2N 5648.0
GRB2 5484.0
IL17RC 5474.0
FAU 5468.0
ITCH 5460.0
HLA-A 5457.0
GEMIN5 5394.0
AP2S1 5363.0
PTPN11 5302.0
HLA-C 5275.0
SIGMAR1 5225.0
FKBP1A 5202.0
CHMP7 5154.0
RPS3 5150.0
TUBB 5134.0
DDX20 5122.0
ST3GAL2 5062.0
SAP30L 4997.0
MOGS 4878.0
G3BP2 4828.0
HLA-F 4775.0
RPS26 4737.0
NUP35 4736.0
RIPK2 4691.0
PARP10 4644.0
CNBP 4640.0
RPS9 4570.0
GEMIN7 4441.0
YWHAZ 4399.0
SNRPD2 4363.0
NFKB1 4199.0
HSP90AA1 4110.0
MASP1 4027.0
VHL 4024.0
SP1 3987.0
TLR2 3956.0
TRIM4 3944.0
RPS8 3907.0
MGAT4C 3781.0
RPS29 3760.0
NFE2L2 3741.0
ARID4A 3715.0
PRKCSH 3701.0
SUMO1 3699.0
IFNAR1 3590.0
NUP133 3541.0
AP2B1 3536.0
YWHAB 3519.0
RBBP4 3444.0
PPIG 3411.0
ISCU 3349.0
SFN 3304.0
CHUK 3247.0
RCOR1 3167.0
PARP9 3138.0
ZDHHC11 3116.0
TRAF6 3111.0
CSNK1A1 3016.0
NUP85 2975.0
PDPK1 2962.0
SEC23A 2953.0
RPS2 2833.0
RPS27L 2825.0
RPS6 2795.0
NPM1 2784.0
TRAF3 2762.0
NUP58 2746.0
FXYD6 2717.0
VAV1 2695.0
RPS15A 2682.0
NUP107 2575.0
CAV1 2544.0
GATAD2B 2518.0
RPS5 2510.0
HDAC2 2417.0
HNRNPA1 2369.0
RIPK3 2334.0
ANO10 2310.0
RPS28 2309.0
TLR1 2278.0
NUP155 2265.0
IL1R1 2129.0
SDC4 2079.0
RPS12 2017.0
NDC1 1928.0
RPS16 1909.0
HMG20B 1862.0
CHMP2A 1810.0
ZCRB1 1778.0
HLA-E 1709.0
RPS10 1666.0
HAVCR1 1643.0
RANBP2 1623.0
FXYD1 1621.0
VPS45 1620.0
PARP4 1404.0
PKLR 1395.0
AKT2 1356.0
KDM1A 1323.0
NR3C1 1306.0
SUDS3 1224.0
ARID4B 1205.0
ST6GALNAC2 1187.0
SNRPD3 1055.0
NRP1 1023.0
PSMC6 933.0
RPN2 867.0
IFNGR2 801.0
MGAT2 783.5
NUP93 757.0
CHD4 671.0
SAR1B 608.0
SEC13 551.0
POM121C 523.0
NUP153 497.0
IRF3 487.0
ATG14 455.0
UBA52 443.0
YWHAG 398.0
CHMP2B 392.0
NUP88 349.0
NUP210 310.0
PLCG2 293.0
SDC1 63.0
GSK3B 32.0
DAD1 -28.0
EEF1A1 -41.0
MTA3 -68.0
SIKE1 -70.0
UBE2V1 -140.0
IFNA16 -210.0
SMAD4 -282.0
RPS25 -336.0
UVRAG -379.0
FXYD7 -381.0
TMPRSS2 -398.0
JAK1 -439.0
SRPK2 -465.0
ISG15 -518.0
SNRPG -533.0
SEC24A -568.0
CUL3 -638.0
IL6R -684.0
KPNA2 -687.0
AP2A2 -802.0
ANO6 -807.0
NUP188 -822.0
BRMS1 -851.0
TLR9 -862.0
SEC24D -884.0
IFNA13 -893.0
DDOST -959.0
TPR -967.0
SAP18 -985.0
GJA1 -1027.0
NUP62 -1072.0
ATP1A1 -1229.0
ANO8 -1312.0
COMT -1368.0
RPS23 -1524.0
RPS27 -1537.0
PRMT1 -1587.0
RCAN3 -1588.0
CHMP4A -1606.0
GALNT1 -1632.0
UBE2I -1641.0
EDEM2 -1647.0
SEH1L -1661.0
SERPINE1 -1675.0
STAT1 -1688.0
SNRPE -1701.0
ATP1B3 -1724.0
RPS20 -1729.0
NUP214 -1861.0
NLRP3 -1885.0
GATAD2A -1942.0
MAP1LC3B -1955.0
ST6GALNAC4 -1978.0
RPS21 -1987.0
NUP160 -2107.0
ATP1B2 -2194.0
MGAT4B -2197.0
RUNX1 -2356.0
JAK3 -2393.0
ZDHHC2 -2410.0
VPS16 -2539.0
ST3GAL1 -2546.0
GANAB -2564.0
PALS1 -2596.0
EP300 -2601.0
RPS24 -2603.0
S1PR1 -2633.0
ATP1B1 -2694.0
CRBN -2720.0
TJP1 -2787.0
AAAS -2886.0
ZDHHC20 -2998.0
TAB1 -3013.0
ANO3 -3017.0
GPC5 -3045.0
NUP205 -3107.0
ATP1A3 -3110.0
KEAP1 -3117.0
VPS39 -3136.0
IMPDH1 -3268.0
GSK3A -3290.0
RB1 -3379.0
SNRPB -3393.0
RPS11 -3542.0
VEGFA -3556.0
TRIM25 -3605.0
GEMIN4 -3673.0
BCL2L1 -3748.0
NUP54 -3926.0
ANO5 -3927.0
PATJ -4042.0
ANO4 -4045.0
TAB2 -4232.0
GPC1 -4354.0
MBD3 -4372.0
SEC24C -4421.0
IFNA14 -4478.0
ROCK2 -4537.0
IFNAR2 -4571.0
SEC24B -4574.0
VPS33B -4652.0
PTPN6 -4696.0
PARP14 -4700.0
IFNA6 -4707.0
ZDHHC3 -4761.0
CRB3 -4836.0
NUP42 -4844.0
ST6GAL1 -4946.0
ATP1A2 -5078.0
STING1 -5114.0
FNTA -5228.0
ANO2 -5284.0
FXYD3 -5298.0
TUSC3 -5343.0
MASP2 -5355.0
STAT2 -5418.0
CHMP6 -5445.0
ZDHHC8 -5647.0
YWHAH -5666.0
ROCK1 -5718.0
CREBBP -5814.0
DDX5 -5832.0
IL17F -5914.0
MGAT5 -6318.0
VPS11 -6349.0
VPS41 -6471.0
IKBKB -6487.0
NUP37 -6563.0
RIPK1 -6575.0
MAN1B1 -6609.0
PTGES3 -6750.0
RNF135 -6780.0
RELA -6863.0
GPC6 -6909.0
AKT3 -7041.0
PDCD1 -7090.0
FXYD2 -7226.0
TYK2 -7457.0
RPS13 -7476.0
RIGI -7493.0
SDC2 -7524.0
JAK2 -7545.0
ST3GAL4 -7605.0
PHF21A -7664.0
IFIH1 -7734.0
YWHAQ -7802.0
ANO9 -7932.0
AP2A1 -8058.0
BECN1 -8094.0
LARP1 -8096.0
ITGB1 -8104.0
VPS33A -8110.0
AKT1 -8221.0
MTA1 -8222.0
SOS1 -8309.0
ST6GALNAC3 -8357.0
REST -8409.0
IL17RA -8567.0
MAN2A1 -8603.0
ZBP1 -8676.0
HSPG2 -8681.0
ST3GAL3 -8787.0
NOD1 -8854.0
CHMP4B -8861.0
FUT8 -8879.0
ANO1 -8915.0
IKBKE -8990.0
FNTB -9009.0
TKFC -9057.0
FXYD4 -9211.0
AP2M1 -9366.0
PIK3R4 -9410.0
VCP -9523.0
HDAC1 -9524.0
IMPDH2 -9591.0
ATP1A4 -9602.0
IFNA21 -9675.0
CTSL -9733.0
IL17A -9947.0
SMAD3 -10027.0
CHD3 -10070.0
BRD4 -10095.0
BLNK -10145.0
CD79B -10378.0
ANO7 -10504.0
NOD2 -10711.0
FURIN -10856.0
MBL2 -11624.0


REACTOME_O_LINKED_GLYCOSYLATION

REACTOME_O_LINKED_GLYCOSYLATION
841
set REACTOME_O_LINKED_GLYCOSYLATION
setSize 109
pANOVA 0.000316
s.dist -0.2
p.adjustANOVA 0.0118



Top enriched genes

Top 20 genes
GeneID Gene Rank
ADAMTS4 -11483
GCNT7 -11242
MUC5AC -11141
MUC4 -10962
MUCL1 -10610
GALNT15 -10531
B4GAT1 -10435
POMGNT2 -10274
MUC13 -9922
LARGE1 -9617
ADAMTS10 -9574
ADAMTSL3 -9494
ADAMTSL1 -9210
ADAMTS2 -9155
ADAMTS5 -9024
ADAMTS16 -8966
THBS1 -8840
ST3GAL3 -8787
MUC15 -8701
GALNT12 -8496

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ADAMTS4 -11483
GCNT7 -11242
MUC5AC -11141
MUC4 -10962
MUCL1 -10610
GALNT15 -10531
B4GAT1 -10435
POMGNT2 -10274
MUC13 -9922
LARGE1 -9617
ADAMTS10 -9574
ADAMTSL3 -9494
ADAMTSL1 -9210
ADAMTS2 -9155
ADAMTS5 -9024
ADAMTS16 -8966
THBS1 -8840
ST3GAL3 -8787
MUC15 -8701
GALNT12 -8496
ST6GALNAC3 -8357
ADAMTS1 -8187
ADAMTS13 -7929
GALNTL5 -7874
C1GALT1 -7850
POFUT2 -7682
ST3GAL4 -7605
CHST4 -7529
THSD4 -7454
GALNT3 -7302
GALNT2 -7199
POMT2 -7104
B3GALNT2 -7052
B3GNT2 -6977
DAG1 -6874
GALNT18 -6836
GALNT14 -6724
POMGNT1 -5950
MUC16 -5888
GCNT1 -5570
GALNT11 -5555
GALNTL6 -5404
ADAMTSL2 -5305
GCNT3 -5293
ADAMTS17 -5244
SSPOP -5236
ADAMTS3 -4974
ST6GAL1 -4946
MUC1 -4902
SPON1 -4878
GALNT10 -4558
ADAMTS15 -4523
THSD7A -4416
MUC6 -3988
THBS2 -3981
B3GNT9 -3920
ADAMTS18 -3802
SBSPON -3751
SEMA5A -3678
POMT1 -3636
ADAMTS20 -3623
GALNT13 -3355
B3GNTL1 -2695
ST3GAL1 -2546
ADAMTS9 -2507
MUC20 -2462
GALNT5 -1981
ST6GALNAC4 -1978
GALNT8 -1674
SPON2 -1668
GALNT1 -1632
GALNT9 -1514
MUC7 -1332
MUC5B -1090
ADAMTS14 -1044
LARGE2 -918
THSD7B -394
GALNT17 -233
THSD1 -181
ADAMTS8 -160
GCNT4 -156
SEMA5B -78
ADAMTS6 141
B3GNT4 507
B3GNT3 737
ADAMTS12 1153
ST6GALNAC2 1187
GALNT6 1664
GALNT7 1747
B3GLCT 2591
POMK 2852
ADAMTS7 3122
ADAMTSL4 4035
B3GNT5 4557
B3GNT7 4623
B4GALT5 4807
ST3GAL2 5062
GALNT16 5165
MUC21 5274
GALNT4 5504
B4GALT6 6136
ADAMTS19 6548
MUC17 6715
B3GNT8 7187
MUC12 7947
A4GNT 8980
MUC3A 9506
B3GNT6 9564
ADAMTSL5 9941


REACTOME_ECM_PROTEOGLYCANS

REACTOME_ECM_PROTEOGLYCANS
537
set REACTOME_ECM_PROTEOGLYCANS
setSize 73
pANOVA 0.00048
s.dist -0.236
p.adjustANOVA 0.0173



Top enriched genes

Top 20 genes
GeneID Gene Rank
MATN3 -10862
ASPN -10689
COL6A3 -9785
TNR -9665
COL6A1 -9490
COL5A1 -9067
ACAN -8954
HSPG2 -8681
TGFB2 -8593
COL4A2 -8323
TNC -8292
DCN -8206
SPARC -8195
ITGB1 -8104
FMOD -7905
FN1 -7731
LAMB2 -7427
NCAM1 -7401
HAPLN1 -7135
VCAN -7040

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MATN3 -10862
ASPN -10689
COL6A3 -9785
TNR -9665
COL6A1 -9490
COL5A1 -9067
ACAN -8954
HSPG2 -8681
TGFB2 -8593
COL4A2 -8323
TNC -8292
DCN -8206
SPARC -8195
ITGB1 -8104
FMOD -7905
FN1 -7731
LAMB2 -7427
NCAM1 -7401
HAPLN1 -7135
VCAN -7040
DAG1 -6874
PTPRS -6857
TGFB3 -6810
DMP1 -6677
MUSK -6558
ITGA2 -6482
COL4A4 -6284
ITGAX -5891
ITGAV -5886
COL4A1 -5804
ITGB3 -5767
TNN -5526
COL5A2 -5327
COL3A1 -5287
MATN4 -5263
DSPP -4749
LAMA1 -4553
COL1A2 -4209
LAMC1 -4096
ITGA2B -4060
COL9A3 -3614
ITGA8 -3603
LRP4 -3477
COL2A1 -3364
ITGB6 -3194
ITGA9 -2767
NCAN -2607
APP -2592
COL6A2 -2375
COL4A3 -2310
LAMA3 -2137
LAMA2 -1754
SERPINE1 -1675
COL6A6 -551
MATN1 -436
ITGB5 -297
TNXB -232
LAMB1 823
COL9A2 851
ITGA7 1186
LAMA5 2177
COL5A3 2328
LUM 3440
COL6A5 3722
COL9A1 4008
COL1A1 4826
LAMA4 4913
TGFB1 5261
AGRN 5753
IBSP 5810
COMP 5813
BCAN 6940
VTN 7424


REACTOME_SIGNALING_BY_ROBO_RECEPTORS

REACTOME_SIGNALING_BY_ROBO_RECEPTORS
605
set REACTOME_SIGNALING_BY_ROBO_RECEPTORS
setSize 206
pANOVA 0.000486
s.dist 0.141
p.adjustANOVA 0.0173



Top enriched genes

Top 20 genes
GeneID Gene Rank
PSMB3 9424
RBM8A 9122
RPS27A 9114
RBX1 9024
RPL19 8794
RPL11 8697
RPL37A 8477
PSMD12 8359
RPLP1 8244
PSMB2 8207
PSME1 8043
RPSA 7996
RPS7 7771
PSMB8 7596
RPL18 7565
NCK1 7516
RPL35 7436
AKAP5 7167
PSMB10 7164
PABPC1 7158

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PSMB3 9424.0
RBM8A 9122.0
RPS27A 9114.0
RBX1 9024.0
RPL19 8794.0
RPL11 8697.0
RPL37A 8477.0
PSMD12 8359.0
RPLP1 8244.0
PSMB2 8207.0
PSME1 8043.0
RPSA 7996.0
RPS7 7771.0
PSMB8 7596.0
RPL18 7565.0
NCK1 7516.0
RPL35 7436.0
AKAP5 7167.0
PSMB10 7164.0
PABPC1 7158.0
LHX9 7133.0
RPL23 7060.0
PRKAR2A 7019.0
RPL7 6970.0
UBC 6955.0
RPS15 6909.0
RPL26L1 6869.0
PFN2 6804.0
RPS3A 6799.0
RPS19 6793.0
PSMD7 6526.0
CLASP2 6327.0
PSMC2 6236.0
PSMB9 6207.0
RPL5 6098.0
RPL4 6052.0
UBB 6050.0
RPL29 5923.0
RPS18 5767.0
RPS14 5716.0
RNPS1 5700.0
PAK1 5615.0
PSMD5 5575.0
PSMD9 5509.0
PRKACG 5493.0
FAU 5468.0
MAGOHB 5392.0
RPL12 5203.0
RPS3 5150.0
PSMA7 4962.0
RPL36 4951.0
RPL7A 4944.0
RPL27 4926.0
UPF3A 4844.0
RPL9 4842.0
LHX2 4840.0
RPS26 4737.0
PSMA1 4589.0
RPL17 4586.0
RPS9 4570.0
GSPT1 4461.0
RPL15 4379.0
RPL31 4222.0
PSMD4 4162.0
ABL2 4161.0
RPL24 4005.0
MYO9B 3959.0
PSMD3 3937.0
RPS8 3907.0
PAK5 3902.0
PSME2 3849.0
RPS29 3760.0
CASC3 3359.0
PSMC5 3212.0
MAGOH 3132.0
PSMA5 2972.0
RPL21 2851.0
PSMB4 2834.0
RPS2 2833.0
RPS27L 2825.0
RPS6 2795.0
RPS15A 2682.0
RPL3 2665.0
PSME3 2641.0
RPL18A 2635.0
RPLP2 2621.0
RPS5 2510.0
SOS2 2502.0
PSMA2 2366.0
CAP2 2364.0
RPS28 2309.0
NCBP2 2256.0
RPL35A 2159.0
RPS12 2017.0
CUL2 1955.0
USP33 1934.0
RPS16 1909.0
NCK2 1895.0
RPS10 1666.0
LDB1 1589.0
RPL39L 1505.0
RPL27A 1261.0
ENAH 1247.0
CAP1 1183.0
RAC1 1036.0
NRP1 1023.0
PSMC6 933.0
PSMA3 884.0
PAK2 871.0
RPL36AL 783.5
RPL3L 780.0
RPL14 642.0
UBA52 443.0
NELL2 395.0
RPL22 335.0
VASP 307.0
UPF2 232.0
PSMA6 176.0
ARHGAP39 -37.0
ROBO1 -139.0
PRKACB -259.0
RPS25 -336.0
RPLP0 -676.0
EIF4G1 -678.0
RPL6 -849.0
PSMD13 -945.0
RPL10A -1071.0
NCBP1 -1089.0
PSMB7 -1254.0
ROBO3 -1279.0
RPS23 -1524.0
RPS27 -1537.0
RPL10L -1553.0
SRC -1560.0
RPS20 -1729.0
PSMC1 -1911.0
RPS21 -1987.0
RHOA -1994.0
PSMB1 -2266.0
CLASP1 -2458.0
RPL13 -2515.0
RPS24 -2603.0
RPL30 -2610.0
RPL34 -2744.0
PSMD1 -2969.0
HOXA2 -3006.0
PAK6 -3062.0
PSMD14 -3064.0
SLIT2 -3072.0
RPL8 -3092.0
EVL -3094.0
PSMB6 -3169.0
CDC42 -3304.0
PSMC4 -3386.0
RPL32 -3472.0
RPS11 -3542.0
SLIT1 -3600.0
RPL37 -3656.0
PSMB5 -3729.0
PFN1 -3812.0
SRGAP3 -3858.0
PPP3CB -3976.0
ROBO2 -4048.0
SEM1 -4068.0
ISL1 -4102.0
PSME4 -4304.0
RPL23A -4330.0
GPC1 -4354.0
RPL38 -4514.0
CXCR4 -4516.0
RPL28 -4919.0
MSI1 -4921.0
PSMC3 -5134.0
PSMD2 -5230.0
PSMD6 -5301.0
PSMA8 -5314.0
ELOB -5434.0
RPL41 -5644.0
RPL22L1 -5689.0
PRKACA -6093.0
DCC -6372.0
PSMD8 -6475.0
SRGAP1 -6504.0
ETF1 -6665.0
RPL13A -6787.5
DAG1 -6874.0
LHX4 -7106.0
CXCL12 -7286.0
EIF4A3 -7299.0
SLIT3 -7394.0
RPS13 -7476.0
ELOC -7792.0
PSMD11 -7848.0
ABL1 -7906.0
RPL26 -8030.0
SOS1 -8309.0
PRKCA -8381.0
FLRT3 -8517.0
NTN1 -8896.0
PSMF1 -9271.0
PAK4 -9540.0
ZSWIM8 -10317.0
PSMA4 -10354.0
LHX3 -10408.0
SRGAP2 -10542.0
PSMB11 -11028.0


REACTOME_DNA_REPLICATION

REACTOME_DNA_REPLICATION
1113
set REACTOME_DNA_REPLICATION
setSize 178
pANOVA 0.000507
s.dist 0.151
p.adjustANOVA 0.0177



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC6 9443
PSMB3 9424
RPS27A 9114
RBX1 9024
H3C12 8871
H4C11 8752
H2BC5 8662
CDC23 8438
H3C6 8421
CDC16 8398
PSMD12 8359
GMNN 8324
POLD4 8307
KPNB1 8280
PSMB2 8207
PSME1 8043
H4C1 7956
ANAPC11 7883
PRIM2 7731
MCM5 7689

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC6 9443.0
PSMB3 9424.0
RPS27A 9114.0
RBX1 9024.0
H3C12 8871.0
H4C11 8752.0
H2BC5 8662.0
CDC23 8438.0
H3C6 8421.0
CDC16 8398.0
PSMD12 8359.0
GMNN 8324.0
POLD4 8307.0
KPNB1 8280.0
PSMB2 8207.0
PSME1 8043.0
H4C1 7956.0
ANAPC11 7883.0
PRIM2 7731.0
MCM5 7689.0
H3-3A 7620.0
PSMB8 7596.0
RPA2 7507.0
H2BC14 7360.0
H2BC13 7347.0
POLE3 7203.0
PSMB10 7164.0
H3C3 6984.0
H2BC3 6957.0
UBC 6955.0
DBF4 6952.0
RFC1 6945.0
ORC5 6733.0
H2AC4 6694.0
H4C13 6661.0
PSMD7 6526.0
ANAPC7 6436.0
H2AZ2 6310.0
PSMC2 6236.0
PSMB9 6207.0
CCNA2 6202.0
POLD1 6182.0
UBB 6050.0
CCNE2 5906.0
ORC2 5616.0
POLE4 5579.0
PSMD5 5575.0
POLE2 5549.0
H3C1 5532.0
PSMD9 5509.0
CDK2 5496.0
H4C3 5422.0
H4C9 5309.0
CDT1 5229.0
H3-3B 5160.0
PSMA7 4962.0
RPA1 4760.0
PSMA1 4589.0
MCM3 4473.0
UBE2C 4308.0
PSMD4 4162.0
H2AC14 4031.0
H2BC12 3963.0
H3C10 3945.0
PSMD3 3937.0
PSME2 3849.0
CCNA1 3743.0
UBE2D1 3621.0
CUL1 3500.0
CDC6 3474.0
PSMC5 3212.0
ANAPC4 3187.0
PSMA5 2972.0
PSMB4 2834.0
H2BC9 2696.5
H3C7 2696.5
PSME3 2641.0
H3C11 2569.0
PRIM1 2456.0
POLA2 2389.0
PSMA2 2366.0
CDC26 2182.0
MCM2 1927.0
MCM8 1757.0
H2BC21 1628.0
H4C4 1608.0
H4C16 1565.0
PCNA 1539.0
ANAPC5 1347.0
RFC5 1161.0
H3C4 958.0
PSMC6 933.0
POLD2 931.0
PSMA3 884.0
FEN1 855.0
H2BC17 820.0
H4C8 810.0
RFC3 686.0
UBA52 443.0
LIG1 292.0
PSMA6 176.0
H4C6 20.0
RFC4 7.0
RFC2 -124.0
KPNA6 -129.0
H2BC11 -531.0
ANAPC16 -645.0
PSMD13 -945.0
CCNE1 -1098.0
GINS2 -1104.0
PSMB7 -1254.0
H2BC15 -1269.0
ANAPC1 -1288.0
ORC4 -1798.0
PSMC1 -1911.0
PSMB1 -2266.0
UBE2E1 -2415.0
ANAPC10 -2472.0
MCM10 -2500.0
H2BC4 -2556.0
H2AC20 -2685.0
ORC3 -2778.0
PSMD1 -2969.0
PSMD14 -3064.0
PSMB6 -3169.0
MCM6 -3273.0
PSMC4 -3386.0
H3C2 -3460.0
MCM4 -3606.0
CDC27 -3640.0
PSMB5 -3729.0
GINS4 -3731.0
H2AC6 -3847.0
CDC7 -3856.0
H2AC7 -3916.5
H2BC7 -3916.5
SEM1 -4068.0
POLD3 -4151.0
PSME4 -4304.0
H4C12 -4954.0
PSMC3 -5134.0
PSMD2 -5230.0
PSMD6 -5301.0
PSMA8 -5314.0
RPA3 -5613.0
H2BC1 -5630.0
POLE -5717.0
UBE2S -5853.0
FZR1 -5912.0
CDC45 -5943.0
H2AZ1 -5992.0
H2AC18 -6150.5
H2AC19 -6150.5
H2BC8 -6266.0
PSMD8 -6475.0
KPNA1 -6645.0
ORC6 -6767.0
SKP2 -6950.0
H3C8 -7012.0
ANAPC2 -7140.0
DNA2 -7158.0
H2AC8 -7163.0
H2AJ -7223.0
SKP1 -7268.0
ANAPC15 -7315.0
PSMD11 -7848.0
ORC1 -8202.0
H4C5 -8476.0
H2BC10 -8762.0
GINS3 -8871.0
PSMF1 -9271.0
MCM7 -9353.0
H2AX -9465.0
GINS1 -9772.0
H4C2 -9982.0
H2BC26 -10312.0
PSMA4 -10354.0
PSMB11 -11028.0


REACTOME_GLOBAL_GENOME_NUCLEOTIDE_EXCISION_REPAIR_GG_NER

REACTOME_GLOBAL_GENOME_NUCLEOTIDE_EXCISION_REPAIR_GG_NER
1022
set REACTOME_GLOBAL_GENOME_NUCLEOTIDE_EXCISION_REPAIR_GG_NER
setSize 81
pANOVA 0.000569
s.dist 0.221
p.adjustANOVA 0.0195



Top enriched genes

Top 20 genes
GeneID Gene Rank
INO80B 9185
COPS5 9129
RPS27A 9114
LIG3 9112
RBX1 9024
ERCC1 8959
ACTB 8951
RAD23A 8679
POLD4 8307
PIAS1 7982
CCNH 7837
UBE2V2 7583
RPA2 7507
GTF2H3 7363
POLE3 7203
COPS7A 7139
UBC 6955
RFC1 6945
COPS2 6610
CHD1L 6520

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
INO80B 9185
COPS5 9129
RPS27A 9114
LIG3 9112
RBX1 9024
ERCC1 8959
ACTB 8951
RAD23A 8679
POLD4 8307
PIAS1 7982
CCNH 7837
UBE2V2 7583
RPA2 7507
GTF2H3 7363
POLE3 7203
COPS7A 7139
UBC 6955
RFC1 6945
COPS2 6610
CHD1L 6520
SUMO2 6497
POLD1 6182
INO80E 6053
UBB 6050
UBE2N 5648
POLE4 5579
POLE2 5549
RNF111 5327
COPS4 4830
RPA1 4760
ACTL6A 4719
SUMO1 3699
POLK 3462
COPS6 2849
DDB2 2640
CDK7 2611
ERCC3 2011
ERCC5 1745
PCNA 1539
USP45 1370
GPS1 1209
RFC5 1161
MNAT1 1110
POLD2 931
INO80D 830
RFC3 686
GTF2H1 604
MCRS1 456
UBA52 443
COPS3 428
TFPT 337
LIG1 292
RFC4 7
RFC2 -124
YY1 -625
INO80C -1060
PARP2 -1176
PARP1 -1343
XPC -1559
UBE2I -1641
NFRKB -1870
INO80 -2141
GTF2H4 -2167
XPA -2217
ERCC4 -2353
POLD3 -4151
ACTR8 -4512
COPS8 -4666
RAD23B -5421
RPA3 -5613
POLE -5717
COPS7B -5868
ERCC2 -6042
GTF2H5 -6365
CUL4A -6743
PIAS3 -8219
SUMO3 -8410
DDB1 -8809
XRCC1 -9124
ACTR5 -10636
RUVBL1 -10852


REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION_TERMINATION

REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION_TERMINATION
1160
set REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION_TERMINATION
setSize 62
pANOVA 0.000633
s.dist 0.251
p.adjustANOVA 0.0212



Top enriched genes

Top 20 genes
GeneID Gene Rank
SRSF7 9328
RBM8A 9122
NUDT21 8884
SYMPK 8342
CLP1 8035
U2AF1L4 8031
DDX39B 7841
LSM11 7805
SNRPF 7761
ALYREF 6915
DDX39A 6712
THOC1 6646
PABPN1 6091
CSTF1 5887
RNPS1 5700
SRSF1 5683
DHX38 5488
THOC3 5410
MAGOHB 5392
CPSF6 5295

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SRSF7 9328
RBM8A 9122
NUDT21 8884
SYMPK 8342
CLP1 8035
U2AF1L4 8031
DDX39B 7841
LSM11 7805
SNRPF 7761
ALYREF 6915
DDX39A 6712
THOC1 6646
PABPN1 6091
CSTF1 5887
RNPS1 5700
SRSF1 5683
DHX38 5488
THOC3 5410
MAGOHB 5392
CPSF6 5295
ZNF473 4578
SRSF2 4219
SRSF6 4086
SRSF11 3999
PAPOLA 3964
SRSF3 3435
CASC3 3359
MAGOH 3132
CPSF7 3055
CPSF2 2928
SRSF4 2891
CPSF1 2683
CPSF3 2377
NCBP2 2256
SARNP 1954
THOC6 1537
SNRPD3 1055
FYTTD1 999
SLU7 730
FIP1L1 322
ZC3H11A -302
SNRPG -533
CDC40 -602
THOC7 -749
SRSF5 -998
NCBP1 -1089
SLBP -1442
SNRPE -1701
PCF11 -2051
SRRM1 -2414
CSTF2T -2890
THOC5 -3161
SNRPB -3393
CHTOP -3569
WDR33 -4088
CPSF4 -4580
LSM10 -7075
EIF4A3 -7299
SRSF9 -7612
U2AF2 -7673
CSTF3 -7860
POLDIP3 -9089


REACTOME_MITOTIC_G2_G2_M_PHASES

REACTOME_MITOTIC_G2_G2_M_PHASES
816
set REACTOME_MITOTIC_G2_G2_M_PHASES
setSize 194
pANOVA 0.000672
s.dist 0.142
p.adjustANOVA 0.0221



Top enriched genes

Top 20 genes
GeneID Gene Rank
TUBB8 10067
PSMB3 9424
CDK11A 9311
RPS27A 9114
RBX1 9024
TUBB2A 9007
TUBB2B 8961
HAUS1 8921
TUBA8 8859
TUBA4B 8804
PLK1 8621
YWHAE 8616
PHLDA1 8580
NEDD1 8453
PSMD12 8359
PSMB2 8207
MZT2A 8145
PSME1 8043
CCNH 7837
XPO1 7719

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TUBB8 10067
PSMB3 9424
CDK11A 9311
RPS27A 9114
RBX1 9024
TUBB2A 9007
TUBB2B 8961
HAUS1 8921
TUBA8 8859
TUBA4B 8804
PLK1 8621
YWHAE 8616
PHLDA1 8580
NEDD1 8453
PSMD12 8359
PSMB2 8207
MZT2A 8145
PSME1 8043
CCNH 7837
XPO1 7719
HAUS8 7599
PSMB8 7596
HSP90AB1 7466
PSMB10 7164
NME7 7095
E2F1 7078
BTRC 7063
UBC 6955
CDC25C 6877
TPX2 6848
MAPRE1 6689
FOXM1 6677
CCNB1 6675
PSMD7 6526
PSMC2 6236
PSMB9 6207
CCNA2 6202
WEE1 6111
UBB 6050
RAB8A 5993
PLK4 5974
TUBB3 5910
TUBA4A 5624
PSMD5 5575
PSMD9 5509
CDK2 5496
LIN37 5470
PCM1 5217
GTSE1 5176
CCNB2 5156
TUBB 5134
FBXL18 4992
OPTN 4979
CSNK1E 4963
PSMA7 4962
PPP1CB 4851
CEP41 4630
PSMA1 4589
PPP2R2A 4552
TUBB4A 4471
PPP2CA 4197
CEP152 4176
PSMD4 4162
DCTN2 4113
HSP90AA1 4110
PSMD3 3937
AURKA 3878
PSME2 3849
CCNA1 3743
CEP135 3507
CUL1 3500
RBBP4 3444
PAFAH1B1 3321
HAUS6 3277
BORA 3257
PSMC5 3212
LIN54 3120
HMMR 3015
PSMA5 2972
PSMB4 2834
CEP57 2787
ALMS1 2692
PSME3 2641
CDK7 2611
CEP43 2527
CEP78 2466
TUBB4B 2387
PSMA2 2366
TUBG1 2291
DYNLL1 2262
TUBG2 2122
TUBA3E 2102
TUBA1A 2084
MZT1 1806
MZT2B 1262
FBXW11 1250
SDCCAG8 1129
MNAT1 1110
SFI1 1018
PSMC6 933
CDKN1A 915
PSMA3 884
CEP250 763
UBA52 443
YWHAG 398
PSMA6 176
CEP290 -73
HAUS3 -111
PRKAR2B -144
CEP76 -522
TP53 -582
DYNC1I2 -731
AKAP9 -836
PSMD13 -945
NDE1 -1155
PSMB7 -1254
PKMYT1 -1355
LIN9 -1568
TUBGCP3 -1609
PPME1 -1614
CKAP5 -1621
PPP2R1A -1758
PSMC1 -1911
TUBA1B -1967
CEP72 -2050
CEP131 -2052
TUBGCP5 -2058
LCMT1 -2177
PSMB1 -2266
CENPJ -2333
FKBPL -2367
CEP63 -2398
CCP110 -2418
TUBGCP6 -2449
CLASP1 -2458
EP300 -2601
MYBL2 -2635
FBXL7 -2717
LIN52 -2918
NEK2 -2930
PSMD1 -2969
PSMD14 -3064
PSMB6 -3169
PSMC4 -3386
CENPF -3728
PSMB5 -3729
CDK11B -3860
SEM1 -4068
HAUS4 -4107
E2F3 -4185
ODF2 -4227
PSME4 -4304
CNTRL -4420
TUBB6 -4579
CEP70 -4671
PPP1R12A -4856
PSMC3 -5134
NINL -5183
PSMD2 -5230
PSMD6 -5301
PSMA8 -5314
PCNT -5740
CEP192 -5906
CDK1 -5988
DCTN1 -6015
HAUS2 -6028
PRKACA -6093
TUBA3C -6096
CDK5RAP2 -6196
SSNA1 -6376
CDC25A -6410
ACTR1A -6470
PSMD8 -6475
TUBA1C -6828
CEP164 -6934
HAUS5 -6972
TUBAL3 -7065
TUBGCP4 -7076
SKP1 -7268
CDC25B -7615
PSMD11 -7848
TUBGCP2 -8171
AJUBA -8363
PPP1R12B -8507
CSNK1D -8860
PSMF1 -9271
PPP2CB -9369
TUBB1 -9794
DCTN3 -10034
PSMA4 -10354
DYNC1H1 -10369
PPP2R1B -10955
PSMB11 -11028
TUBA3D -11433


Here is the session info with all the versions of packages used.

sessionInfo()
## R version 4.3.2 (2023-10-31)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.3 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3 
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so;  LAPACK version 3.10.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Etc/UTC
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.3.3                                      
##  [2] GGally_2.2.0                                       
##  [3] ggplot2_3.4.4                                      
##  [4] reshape2_1.4.4                                     
##  [5] gtools_3.9.5                                       
##  [6] tibble_3.2.1                                       
##  [7] dplyr_1.1.4                                        
##  [8] echarts4r_0.4.5                                    
##  [9] png_0.1-8                                          
## [10] gridExtra_2.3                                      
## [11] missMethyl_1.36.0                                  
## [12] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.1 
## [13] beeswarm_0.4.0                                     
## [14] kableExtra_1.3.4                                   
## [15] gplots_3.1.3                                       
## [16] mitch_1.15.0                                       
## [17] tictoc_1.2                                         
## [18] HGNChelper_0.8.1                                   
## [19] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [20] IlluminaHumanMethylation450kmanifest_0.4.0         
## [21] minfi_1.48.0                                       
## [22] bumphunter_1.44.0                                  
## [23] locfit_1.5-9.8                                     
## [24] iterators_1.0.14                                   
## [25] foreach_1.5.2                                      
## [26] Biostrings_2.70.1                                  
## [27] XVector_0.42.0                                     
## [28] SummarizedExperiment_1.32.0                        
## [29] Biobase_2.62.0                                     
## [30] MatrixGenerics_1.14.0                              
## [31] matrixStats_1.2.0                                  
## [32] GenomicRanges_1.54.1                               
## [33] GenomeInfoDb_1.38.2                                
## [34] IRanges_2.36.0                                     
## [35] S4Vectors_0.40.2                                   
## [36] BiocGenerics_0.48.1                                
## [37] eulerr_7.0.0                                       
## [38] limma_3.58.1                                       
## 
## loaded via a namespace (and not attached):
##   [1] splines_4.3.2             later_1.3.2              
##   [3] BiocIO_1.12.0             bitops_1.0-7             
##   [5] filelock_1.0.3            preprocessCore_1.64.0    
##   [7] XML_3.99-0.16             lifecycle_1.0.4          
##   [9] lattice_0.22-5            MASS_7.3-60              
##  [11] base64_2.0.1              scrime_1.3.5             
##  [13] magrittr_2.0.3            sass_0.4.8               
##  [15] rmarkdown_2.25            jquerylib_0.1.4          
##  [17] yaml_2.3.8                httpuv_1.6.13            
##  [19] doRNG_1.8.6               askpass_1.2.0            
##  [21] DBI_1.1.3                 RColorBrewer_1.1-3       
##  [23] abind_1.4-5               zlibbioc_1.48.0          
##  [25] rvest_1.0.3               quadprog_1.5-8           
##  [27] purrr_1.0.2               RCurl_1.98-1.13          
##  [29] rappdirs_0.3.3            GenomeInfoDbData_1.2.11  
##  [31] genefilter_1.84.0         annotate_1.80.0          
##  [33] svglite_2.1.3             DelayedMatrixStats_1.24.0
##  [35] codetools_0.2-19          DelayedArray_0.28.0      
##  [37] xml2_1.3.6                tidyselect_1.2.0         
##  [39] beanplot_1.3.1            BiocFileCache_2.10.1     
##  [41] webshot_0.5.5             illuminaio_0.44.0        
##  [43] GenomicAlignments_1.38.0  jsonlite_1.8.8           
##  [45] multtest_2.58.0           ellipsis_0.3.2           
##  [47] survival_3.5-7            systemfonts_1.0.5        
##  [49] tools_4.3.2               progress_1.2.3           
##  [51] Rcpp_1.0.11               glue_1.6.2               
##  [53] SparseArray_1.2.2         xfun_0.41                
##  [55] HDF5Array_1.30.0          withr_2.5.2              
##  [57] fastmap_1.1.1             rhdf5filters_1.14.1      
##  [59] fansi_1.0.6               openssl_2.1.1            
##  [61] caTools_1.18.2            digest_0.6.33            
##  [63] R6_2.5.1                  mime_0.12                
##  [65] colorspace_2.1-0          biomaRt_2.58.0           
##  [67] RSQLite_2.3.4             utf8_1.2.4               
##  [69] tidyr_1.3.0               generics_0.1.3           
##  [71] data.table_1.14.10        rtracklayer_1.62.0       
##  [73] prettyunits_1.2.0         httr_1.4.7               
##  [75] htmlwidgets_1.6.4         S4Arrays_1.2.0           
##  [77] ggstats_0.5.1             pkgconfig_2.0.3          
##  [79] gtable_0.3.4              blob_1.2.4               
##  [81] siggenes_1.76.0           htmltools_0.5.7          
##  [83] scales_1.3.0              rstudioapi_0.15.0        
##  [85] knitr_1.45                tzdb_0.4.0               
##  [87] rjson_0.2.21              nlme_3.1-163             
##  [89] curl_5.2.0                org.Hs.eg.db_3.18.0      
##  [91] cachem_1.0.8              rhdf5_2.46.1             
##  [93] stringr_1.5.1             KernSmooth_2.23-22       
##  [95] AnnotationDbi_1.64.1      restfulr_0.0.15          
##  [97] GEOquery_2.70.0           pillar_1.9.0             
##  [99] grid_4.3.2                reshape_0.8.9            
## [101] vctrs_0.6.5               promises_1.2.1           
## [103] dbplyr_2.4.0              xtable_1.8-4             
## [105] evaluate_0.23             readr_2.1.4              
## [107] GenomicFeatures_1.54.1    cli_3.6.2                
## [109] compiler_4.3.2            Rsamtools_2.18.0         
## [111] rlang_1.1.2               crayon_1.5.2             
## [113] rngtools_1.5.2            nor1mix_1.3-2            
## [115] mclust_6.0.1              plyr_1.8.9               
## [117] stringi_1.8.3             viridisLite_0.4.2        
## [119] BiocParallel_1.36.0       munsell_0.5.0            
## [121] Matrix_1.6-1.1            hms_1.1.3                
## [123] sparseMatrixStats_1.14.0  bit64_4.0.5              
## [125] Rhdf5lib_1.24.1           KEGGREST_1.42.0          
## [127] statmod_1.5.0             shiny_1.8.0              
## [129] highr_0.10                memoise_2.0.1            
## [131] bslib_0.6.1               bit_4.0.5

END of report