Mitch Report
Antony Kaspi & Mark Ziemann
date generated: 2024-01-18
Background
Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch
Input profiles
Here is the first few lines of the input profile.
| x | |
|---|---|
| A1BG | 0.0002302 |
| A1BG-AS1 | -0.0019562 |
| A1CF | -0.0031212 |
| A2M | 0.0034058 |
| A2M-AS1 | -0.0027084 |
| A2ML1 | -0.0045963 |
Here are some metrics about the input data profile:
| Profile metrics | |
|---|---|
| num_genesets | 1654 |
| num_genes_in_profile | 22007 |
| duplicated_genes_present | 0 |
| num_profile_genes_in_sets | 10383 |
| num_profile_genes_not_in_sets | 11624 |
Here is a plot of the input profiles. Note the dynamic ranges.
Here is the contour plot of the profile including all detected genes.
Input genesets
Here are some metrics about the gene sets used:
GMT file of genesets: c2.cp.reactome.v2023.1.Hs.symbols.gmt| Gene sets metrics | |
|---|---|
| num_genesets | 1654 |
| num_genesets_excluded | 365 |
| num_genesets_included | 1289 |
Differential pathway expression
Interactive enrichment scatterplot
Significance is calculated by -log10(p-value). All points shown are
FDR<0.05.
Significance is calculated by -log10(p-value). Top N sets shown
irrespective of FDR.
Results table
Top N= 50 gene sets
## Warning in kable_styling(., "hover", full_width = FALSE): Please specify format
## in kable. kableExtra can customize either HTML or LaTeX outputs. See
## https://haozhu233.github.io/kableExtra/ for details.| set | setSize | pANOVA | s.dist | p.adjustANOVA |
|---|---|---|---|---|
| REACTOME METABOLISM OF RNA | 675 | 5.27e-17 | 0.1890 | 8.65e-14 |
| REACTOME CELLULAR RESPONSES TO STIMULI | 779 | 4.39e-14 | 0.1590 | 3.61e-11 |
| REACTOME TRANSLATION | 278 | 3.48e-09 | 0.2060 | 1.62e-06 |
| REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS | 161 | 3.95e-09 | 0.2690 | 1.62e-06 |
| REACTOME SENSORY PERCEPTION | 555 | 7.16e-09 | -0.1440 | 2.35e-06 |
| REACTOME RNA POLYMERASE II TRANSCRIPTION | 1336 | 2.71e-08 | 0.0906 | 7.41e-06 |
| REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | 105 | 1.44e-07 | 0.2970 | 3.39e-05 |
| REACTOME RRNA PROCESSING | 192 | 3.11e-07 | 0.2140 | 6.39e-05 |
| REACTOME CELLULAR RESPONSE TO STARVATION | 147 | 3.60e-07 | 0.2430 | 6.56e-05 |
| REACTOME EUKARYOTIC TRANSLATION INITIATION | 110 | 5.47e-07 | 0.2760 | 8.97e-05 |
| REACTOME CELL CYCLE CHECKPOINTS | 284 | 6.48e-07 | 0.1720 | 9.68e-05 |
| REACTOME SIGNALING BY ROBO RECEPTORS | 206 | 7.56e-07 | 0.2000 | 1.02e-04 |
| REACTOME INFECTIOUS DISEASE | 910 | 8.06e-07 | 0.0964 | 1.02e-04 |
| REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY | 94 | 9.45e-07 | 0.2930 | 1.11e-04 |
| REACTOME EUKARYOTIC TRANSLATION ELONGATION | 87 | 1.36e-06 | 0.3000 | 1.49e-04 |
| REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | 263 | 1.84e-06 | 0.1710 | 1.88e-04 |
| REACTOME KERATINIZATION | 210 | 4.50e-06 | -0.1840 | 4.34e-04 |
| REACTOME UNFOLDED PROTEIN RESPONSE UPR | 88 | 5.96e-06 | 0.2790 | 5.44e-04 |
| REACTOME MRNA SPLICING | 197 | 6.41e-06 | 0.1860 | 5.54e-04 |
| REACTOME OLFACTORY SIGNALING PATHWAY | 348 | 7.18e-06 | -0.1400 | 5.66e-04 |
| REACTOME CELL CYCLE | 666 | 7.24e-06 | 0.1020 | 5.66e-04 |
| REACTOME INNATE IMMUNE SYSTEM | 1002 | 7.58e-06 | 0.0836 | 5.66e-04 |
| REACTOME NONSENSE MEDIATED DECAY NMD | 107 | 8.57e-06 | 0.2490 | 6.12e-04 |
| REACTOME DNA REPLICATION | 178 | 9.15e-06 | 0.1930 | 6.26e-04 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS | 121 | 1.28e-05 | 0.2300 | 8.04e-04 |
| REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS | 83 | 1.30e-05 | 0.2770 | 8.04e-04 |
| REACTOME MITOTIC METAPHASE AND ANAPHASE | 228 | 1.32e-05 | 0.1670 | 8.04e-04 |
| REACTOME CELL CYCLE MITOTIC | 539 | 2.11e-05 | 0.1070 | 1.22e-03 |
| REACTOME G2 M CHECKPOINTS | 162 | 2.21e-05 | 0.1930 | 1.22e-03 |
| REACTOME FORMATION OF THE CORNIFIED ENVELOPE | 125 | 2.27e-05 | -0.2190 | 1.22e-03 |
| REACTOME CELLULAR SENESCENCE | 189 | 2.31e-05 | 0.1790 | 1.22e-03 |
| REACTOME DNA REPLICATION PRE INITIATION | 150 | 2.41e-05 | 0.2000 | 1.24e-03 |
| REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM | 688 | 3.19e-05 | 0.0930 | 1.59e-03 |
| REACTOME INFLUENZA INFECTION | 149 | 3.33e-05 | 0.1970 | 1.61e-03 |
| REACTOME PROTEIN LOCALIZATION | 153 | 5.19e-05 | 0.1900 | 2.43e-03 |
| REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | 86 | 1.05e-04 | 0.2420 | 4.78e-03 |
| REACTOME OXIDATIVE STRESS INDUCED SENESCENCE | 118 | 1.50e-04 | 0.2020 | 6.67e-03 |
| REACTOME TRANSCRIPTIONAL REGULATION BY TP53 | 351 | 1.63e-04 | 0.1170 | 6.98e-03 |
| REACTOME SEPARATION OF SISTER CHROMATIDS | 184 | 1.66e-04 | 0.1610 | 6.98e-03 |
| REACTOME DNA REPAIR | 321 | 1.98e-04 | 0.1210 | 8.14e-03 |
| REACTOME RNA POLYMERASE I PROMOTER ESCAPE | 83 | 2.23e-04 | 0.2340 | 8.92e-03 |
| REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP | 104 | 2.47e-04 | 0.2080 | 9.66e-03 |
| REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION | 98 | 2.69e-04 | 0.2130 | 1.03e-02 |
| REACTOME SIGNALING BY CSF3 G CSF | 30 | 3.20e-04 | 0.3800 | 1.18e-02 |
| REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION | 84 | 3.24e-04 | 0.2270 | 1.18e-02 |
| REACTOME PEROXISOMAL PROTEIN IMPORT | 62 | 3.30e-04 | 0.2640 | 1.18e-02 |
| REACTOME S PHASE | 159 | 3.58e-04 | 0.1640 | 1.25e-02 |
| REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | 39 | 3.76e-04 | -0.3290 | 1.28e-02 |
| REACTOME M PHASE | 398 | 3.96e-04 | 0.1030 | 1.33e-02 |
| REACTOME G1 S DNA DAMAGE CHECKPOINTS | 67 | 4.16e-04 | 0.2490 | 1.37e-02 |
Results (complete table)
Click HERE to show results for all gene sets
| set | setSize | pANOVA | s.dist | p.adjustANOVA |
|---|---|---|---|---|
| REACTOME METABOLISM OF RNA | 675 | 5.27e-17 | 1.89e-01 | 8.65e-14 |
| REACTOME CELLULAR RESPONSES TO STIMULI | 779 | 4.39e-14 | 1.59e-01 | 3.61e-11 |
| REACTOME TRANSLATION | 278 | 3.48e-09 | 2.06e-01 | 1.62e-06 |
| REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS | 161 | 3.95e-09 | 2.69e-01 | 1.62e-06 |
| REACTOME SENSORY PERCEPTION | 555 | 7.16e-09 | -1.44e-01 | 2.35e-06 |
| REACTOME RNA POLYMERASE II TRANSCRIPTION | 1336 | 2.71e-08 | 9.06e-02 | 7.41e-06 |
| REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | 105 | 1.44e-07 | 2.97e-01 | 3.39e-05 |
| REACTOME RRNA PROCESSING | 192 | 3.11e-07 | 2.14e-01 | 6.39e-05 |
| REACTOME CELLULAR RESPONSE TO STARVATION | 147 | 3.60e-07 | 2.43e-01 | 6.56e-05 |
| REACTOME EUKARYOTIC TRANSLATION INITIATION | 110 | 5.47e-07 | 2.76e-01 | 8.97e-05 |
| REACTOME CELL CYCLE CHECKPOINTS | 284 | 6.48e-07 | 1.72e-01 | 9.68e-05 |
| REACTOME SIGNALING BY ROBO RECEPTORS | 206 | 7.56e-07 | 2.00e-01 | 1.02e-04 |
| REACTOME INFECTIOUS DISEASE | 910 | 8.06e-07 | 9.64e-02 | 1.02e-04 |
| REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY | 94 | 9.45e-07 | 2.93e-01 | 1.11e-04 |
| REACTOME EUKARYOTIC TRANSLATION ELONGATION | 87 | 1.36e-06 | 3.00e-01 | 1.49e-04 |
| REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | 263 | 1.84e-06 | 1.71e-01 | 1.88e-04 |
| REACTOME KERATINIZATION | 210 | 4.50e-06 | -1.84e-01 | 4.34e-04 |
| REACTOME UNFOLDED PROTEIN RESPONSE UPR | 88 | 5.96e-06 | 2.79e-01 | 5.44e-04 |
| REACTOME MRNA SPLICING | 197 | 6.41e-06 | 1.86e-01 | 5.54e-04 |
| REACTOME OLFACTORY SIGNALING PATHWAY | 348 | 7.18e-06 | -1.40e-01 | 5.66e-04 |
| REACTOME CELL CYCLE | 666 | 7.24e-06 | 1.02e-01 | 5.66e-04 |
| REACTOME INNATE IMMUNE SYSTEM | 1002 | 7.58e-06 | 8.36e-02 | 5.66e-04 |
| REACTOME NONSENSE MEDIATED DECAY NMD | 107 | 8.57e-06 | 2.49e-01 | 6.12e-04 |
| REACTOME DNA REPLICATION | 178 | 9.15e-06 | 1.93e-01 | 6.26e-04 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS | 121 | 1.28e-05 | 2.30e-01 | 8.04e-04 |
| REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS | 83 | 1.30e-05 | 2.77e-01 | 8.04e-04 |
| REACTOME MITOTIC METAPHASE AND ANAPHASE | 228 | 1.32e-05 | 1.67e-01 | 8.04e-04 |
| REACTOME CELL CYCLE MITOTIC | 539 | 2.11e-05 | 1.07e-01 | 1.22e-03 |
| REACTOME G2 M CHECKPOINTS | 162 | 2.21e-05 | 1.93e-01 | 1.22e-03 |
| REACTOME FORMATION OF THE CORNIFIED ENVELOPE | 125 | 2.27e-05 | -2.19e-01 | 1.22e-03 |
| REACTOME CELLULAR SENESCENCE | 189 | 2.31e-05 | 1.79e-01 | 1.22e-03 |
| REACTOME DNA REPLICATION PRE INITIATION | 150 | 2.41e-05 | 2.00e-01 | 1.24e-03 |
| REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM | 688 | 3.19e-05 | 9.30e-02 | 1.59e-03 |
| REACTOME INFLUENZA INFECTION | 149 | 3.33e-05 | 1.97e-01 | 1.61e-03 |
| REACTOME PROTEIN LOCALIZATION | 153 | 5.19e-05 | 1.90e-01 | 2.43e-03 |
| REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | 86 | 1.05e-04 | 2.42e-01 | 4.78e-03 |
| REACTOME OXIDATIVE STRESS INDUCED SENESCENCE | 118 | 1.50e-04 | 2.02e-01 | 6.67e-03 |
| REACTOME TRANSCRIPTIONAL REGULATION BY TP53 | 351 | 1.63e-04 | 1.17e-01 | 6.98e-03 |
| REACTOME SEPARATION OF SISTER CHROMATIDS | 184 | 1.66e-04 | 1.61e-01 | 6.98e-03 |
| REACTOME DNA REPAIR | 321 | 1.98e-04 | 1.21e-01 | 8.14e-03 |
| REACTOME RNA POLYMERASE I PROMOTER ESCAPE | 83 | 2.23e-04 | 2.34e-01 | 8.92e-03 |
| REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP | 104 | 2.47e-04 | 2.08e-01 | 9.66e-03 |
| REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION | 98 | 2.69e-04 | 2.13e-01 | 1.03e-02 |
| REACTOME SIGNALING BY CSF3 G CSF | 30 | 3.20e-04 | 3.80e-01 | 1.18e-02 |
| REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION | 84 | 3.24e-04 | 2.27e-01 | 1.18e-02 |
| REACTOME PEROXISOMAL PROTEIN IMPORT | 62 | 3.30e-04 | 2.64e-01 | 1.18e-02 |
| REACTOME S PHASE | 159 | 3.58e-04 | 1.64e-01 | 1.25e-02 |
| REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | 39 | 3.76e-04 | -3.29e-01 | 1.28e-02 |
| REACTOME M PHASE | 398 | 3.96e-04 | 1.03e-01 | 1.33e-02 |
| REACTOME G1 S DNA DAMAGE CHECKPOINTS | 67 | 4.16e-04 | 2.49e-01 | 1.37e-02 |
| REACTOME APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS | 87 | 4.84e-04 | 2.16e-01 | 1.56e-02 |
| REACTOME RNA POLYMERASE I TRANSCRIPTION | 102 | 5.03e-04 | 1.99e-01 | 1.59e-02 |
| REACTOME STABILIZATION OF P53 | 56 | 5.42e-04 | 2.67e-01 | 1.68e-02 |
| REACTOME ORC1 REMOVAL FROM CHROMATIN | 70 | 5.71e-04 | 2.38e-01 | 1.74e-02 |
| REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1 | 229 | 5.87e-04 | 1.32e-01 | 1.75e-02 |
| REACTOME IRE1ALPHA ACTIVATES CHAPERONES | 48 | 6.42e-04 | 2.85e-01 | 1.88e-02 |
| REACTOME DEGRADATION OF GLI1 BY THE PROTEASOME | 59 | 6.90e-04 | 2.55e-01 | 1.96e-02 |
| REACTOME AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA | 54 | 6.91e-04 | 2.67e-01 | 1.96e-02 |
| REACTOME SELENOAMINO ACID METABOLISM | 108 | 7.35e-04 | 1.88e-01 | 2.05e-02 |
| REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION | 62 | 7.57e-04 | 2.47e-01 | 2.07e-02 |
| REACTOME HIV INFECTION | 223 | 7.81e-04 | 1.31e-01 | 2.10e-02 |
| REACTOME UCH PROTEINASES | 99 | 8.80e-04 | 1.93e-01 | 2.33e-02 |
| REACTOME HOMOLOGY DIRECTED REPAIR | 132 | 9.10e-04 | 1.67e-01 | 2.37e-02 |
| REACTOME ADAPTIVE IMMUNE SYSTEM | 729 | 9.31e-04 | 7.20e-02 | 2.39e-02 |
| REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION | 1356 | 9.56e-04 | 5.35e-02 | 2.41e-02 |
| REACTOME CELLULAR RESPONSE TO HYPOXIA | 74 | 9.94e-04 | 2.21e-01 | 2.47e-02 |
| REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY | 46 | 1.05e-03 | 2.79e-01 | 2.57e-02 |
| REACTOME INSULIN RECEPTOR RECYCLING | 29 | 1.07e-03 | 3.51e-01 | 2.57e-02 |
| REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | 53 | 1.11e-03 | 2.59e-01 | 2.61e-02 |
| REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS | 188 | 1.11e-03 | 1.38e-01 | 2.61e-02 |
| REACTOME ANTIGEN PROCESSING CROSS PRESENTATION | 98 | 1.13e-03 | 1.90e-01 | 2.61e-02 |
| REACTOME SIGNALING BY INTERLEUKINS | 444 | 1.16e-03 | 8.99e-02 | 2.64e-02 |
| REACTOME TNFR2 NON CANONICAL NF KB PATHWAY | 96 | 1.19e-03 | 1.91e-01 | 2.65e-02 |
| REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION | 89 | 1.20e-03 | 1.99e-01 | 2.65e-02 |
| REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS | 60 | 1.30e-03 | 2.40e-01 | 2.85e-02 |
| REACTOME ONCOGENE INDUCED SENESCENCE | 35 | 1.32e-03 | 3.14e-01 | 2.86e-02 |
| REACTOME SYNTHESIS OF DNA | 119 | 1.37e-03 | 1.70e-01 | 2.92e-02 |
| REACTOME MEIOTIC RECOMBINATION | 80 | 1.39e-03 | 2.07e-01 | 2.93e-02 |
| REACTOME SIGNALING BY THE B CELL RECEPTOR BCR | 106 | 1.47e-03 | 1.79e-01 | 3.03e-02 |
| REACTOME DEGRADATION OF DVL | 56 | 1.48e-03 | 2.46e-01 | 3.03e-02 |
| REACTOME HEDGEHOG LIGAND BIOGENESIS | 64 | 1.51e-03 | 2.29e-01 | 3.06e-02 |
| REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION | 100 | 1.56e-03 | 1.83e-01 | 3.13e-02 |
| REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | 111 | 1.59e-03 | 1.73e-01 | 3.15e-02 |
| REACTOME APOPTOSIS | 173 | 1.65e-03 | 1.39e-01 | 3.20e-02 |
| REACTOME HOST INTERACTIONS OF HIV FACTORS | 127 | 1.66e-03 | 1.62e-01 | 3.20e-02 |
| REACTOME SENSORY PERCEPTION OF TASTE | 47 | 1.70e-03 | -2.64e-01 | 3.24e-02 |
| REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION | 138 | 1.72e-03 | 1.55e-01 | 3.24e-02 |
| REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 | 54 | 1.80e-03 | 2.45e-01 | 3.36e-02 |
| REACTOME PROCESSING OF DNA DOUBLE STRAND BREAK ENDS | 93 | 1.93e-03 | 1.86e-01 | 3.52e-02 |
| REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | 73 | 1.93e-03 | 2.10e-01 | 3.52e-02 |
| REACTOME NEUTROPHIL DEGRANULATION | 460 | 1.95e-03 | 8.43e-02 | 3.52e-02 |
| REACTOME SUMOYLATION | 179 | 2.04e-03 | 1.34e-01 | 3.64e-02 |
| REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | 134 | 2.07e-03 | -1.54e-01 | 3.65e-02 |
| REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION | 145 | 2.13e-03 | 1.48e-01 | 3.71e-02 |
| REACTOME PROGRAMMED CELL DEATH | 204 | 2.30e-03 | 1.24e-01 | 3.98e-02 |
| REACTOME SARS COV 2 HOST INTERACTIONS | 191 | 2.40e-03 | 1.27e-01 | 4.07e-02 |
| REACTOME SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE | 91 | 2.40e-03 | 1.84e-01 | 4.07e-02 |
| REACTOME EXTRACELLULAR MATRIX ORGANIZATION | 291 | 2.43e-03 | -1.03e-01 | 4.07e-02 |
| REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY | 33 | 2.48e-03 | 3.04e-01 | 4.12e-02 |
| REACTOME FLT3 SIGNALING | 38 | 2.71e-03 | 2.81e-01 | 4.45e-02 |
| REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | 353 | 2.93e-03 | 9.21e-02 | 4.77e-02 |
| REACTOME MAPK6 MAPK4 SIGNALING | 91 | 3.24e-03 | 1.79e-01 | 5.22e-02 |
| REACTOME MITOCHONDRIAL TRANSLATION | 93 | 3.33e-03 | 1.76e-01 | 5.26e-02 |
| REACTOME METABOLISM OF FAT SOLUBLE VITAMINS | 46 | 3.33e-03 | -2.50e-01 | 5.26e-02 |
| REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION | 62 | 3.43e-03 | 2.15e-01 | 5.37e-02 |
| REACTOME CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY | 84 | 3.74e-03 | 1.83e-01 | 5.80e-02 |
| REACTOME INACTIVATION OF CSF3 G CSF SIGNALING | 25 | 3.82e-03 | 3.34e-01 | 5.86e-02 |
| REACTOME HDACS DEACETYLATE HISTONES | 85 | 3.86e-03 | 1.81e-01 | 5.87e-02 |
| REACTOME METABOLISM OF POLYAMINES | 56 | 4.01e-03 | 2.22e-01 | 6.04e-02 |
| REACTOME DNA DOUBLE STRAND BREAK REPAIR | 162 | 4.32e-03 | 1.30e-01 | 6.44e-02 |
| REACTOME RMTS METHYLATE HISTONE ARGININES | 72 | 4.39e-03 | 1.94e-01 | 6.45e-02 |
| REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | 129 | 4.40e-03 | 1.45e-01 | 6.45e-02 |
| REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS | 418 | 4.47e-03 | 8.10e-02 | 6.50e-02 |
| REACTOME ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION | 16 | 4.67e-03 | 4.08e-01 | 6.73e-02 |
| REACTOME BH3 ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI APOPTOTIC BCL 2 MEMBERS | 9 | 4.77e-03 | 5.43e-01 | 6.82e-02 |
| REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT | 222 | 4.96e-03 | 1.09e-01 | 7.02e-02 |
| REACTOME SARS COV 1 HOST INTERACTIONS | 92 | 5.01e-03 | 1.69e-01 | 7.03e-02 |
| REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION | 90 | 5.07e-03 | 1.71e-01 | 7.05e-02 |
| REACTOME TCR SIGNALING | 113 | 5.20e-03 | 1.52e-01 | 7.18e-02 |
| REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21 | 59 | 5.32e-03 | 2.10e-01 | 7.28e-02 |
| REACTOME PTEN REGULATION | 135 | 5.51e-03 | 1.38e-01 | 7.48e-02 |
| REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | 28 | 5.68e-03 | 3.02e-01 | 7.62e-02 |
| REACTOME REGULATION OF RUNX3 EXPRESSION AND ACTIVITY | 54 | 5.70e-03 | 2.17e-01 | 7.62e-02 |
| REACTOME THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT | 77 | 5.81e-03 | 1.82e-01 | 7.66e-02 |
| REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION | 68 | 5.83e-03 | 1.93e-01 | 7.66e-02 |
| REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES | 34 | 6.27e-03 | 2.71e-01 | 8.12e-02 |
| REACTOME DEADENYLATION DEPENDENT MRNA DECAY | 56 | 6.28e-03 | 2.11e-01 | 8.12e-02 |
| REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY | 72 | 6.42e-03 | 1.86e-01 | 8.24e-02 |
| REACTOME REGULATION OF TP53 ACTIVITY | 156 | 6.65e-03 | 1.26e-01 | 8.46e-02 |
| REACTOME DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING | 61 | 6.76e-03 | 2.01e-01 | 8.53e-02 |
| REACTOME SARS COV INFECTIONS | 392 | 6.92e-03 | 7.95e-02 | 8.67e-02 |
| REACTOME RHO GTPASE EFFECTORS | 305 | 7.05e-03 | 8.97e-02 | 8.77e-02 |
| REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE | 109 | 7.51e-03 | 1.48e-01 | 9.21e-02 |
| REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON | 17 | 7.56e-03 | 3.74e-01 | 9.21e-02 |
| REACTOME MITOTIC SPINDLE CHECKPOINT | 109 | 7.57e-03 | 1.48e-01 | 9.21e-02 |
| REACTOME SIGNALING BY INSULIN RECEPTOR | 80 | 7.93e-03 | 1.72e-01 | 9.57e-02 |
| REACTOME SIGNALING BY NOTCH | 234 | 8.31e-03 | 1.00e-01 | 9.91e-02 |
| REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | 16 | 8.37e-03 | 3.81e-01 | 9.91e-02 |
| REACTOME GPVI MEDIATED ACTIVATION CASCADE | 35 | 8.42e-03 | 2.57e-01 | 9.91e-02 |
| REACTOME CHROMATIN MODIFYING ENZYMES | 252 | 8.45e-03 | 9.63e-02 | 9.91e-02 |
| REACTOME ASPIRIN ADME | 42 | 8.60e-03 | -2.34e-01 | 9.95e-02 |
| REACTOME FLT3 SIGNALING IN DISEASE | 28 | 8.61e-03 | 2.87e-01 | 9.95e-02 |
| REACTOME CHROMOSOME MAINTENANCE | 130 | 8.87e-03 | 1.33e-01 | 1.02e-01 |
| REACTOME RESPIRATORY ELECTRON TRANSPORT | 90 | 9.26e-03 | 1.59e-01 | 1.05e-01 |
| REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS | 63 | 9.29e-03 | 1.89e-01 | 1.05e-01 |
| REACTOME NEGATIVE REGULATION OF NOTCH4 SIGNALING | 53 | 9.36e-03 | 2.06e-01 | 1.05e-01 |
| REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT | 159 | 9.56e-03 | 1.19e-01 | 1.07e-01 |
| REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3 | 59 | 9.62e-03 | 1.95e-01 | 1.07e-01 |
| REACTOME HS GAG BIOSYNTHESIS | 28 | 1.12e-02 | -2.77e-01 | 1.24e-01 |
| REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER | 81 | 1.14e-02 | 1.63e-01 | 1.24e-01 |
| REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING | 45 | 1.15e-02 | 2.18e-01 | 1.24e-01 |
| REACTOME CALNEXIN CALRETICULIN CYCLE | 26 | 1.15e-02 | 2.86e-01 | 1.24e-01 |
| REACTOME PRE NOTCH EXPRESSION AND PROCESSING | 112 | 1.17e-02 | 1.38e-01 | 1.25e-01 |
| REACTOME ALPHA DEFENSINS | 6 | 1.17e-02 | -5.94e-01 | 1.25e-01 |
| REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION | 60 | 1.19e-02 | 1.88e-01 | 1.25e-01 |
| REACTOME TELOMERE MAINTENANCE | 106 | 1.19e-02 | 1.41e-01 | 1.25e-01 |
| REACTOME FCERI MEDIATED NF KB ACTIVATION | 78 | 1.19e-02 | 1.65e-01 | 1.25e-01 |
| REACTOME DEGRADATION OF AXIN | 54 | 1.21e-02 | 1.97e-01 | 1.25e-01 |
| REACTOME SUMO IS TRANSFERRED FROM E1 TO E2 UBE2I UBC9 | 7 | 1.21e-02 | 5.48e-01 | 1.25e-01 |
| REACTOME MITOCHONDRIAL BIOGENESIS | 87 | 1.24e-02 | 1.55e-01 | 1.28e-01 |
| REACTOME RESOLUTION OF SISTER CHROMATID COHESION | 120 | 1.27e-02 | 1.32e-01 | 1.29e-01 |
| REACTOME MET PROMOTES CELL MOTILITY | 41 | 1.28e-02 | -2.25e-01 | 1.29e-01 |
| REACTOME CARDIAC CONDUCTION | 125 | 1.35e-02 | -1.28e-01 | 1.36e-01 |
| REACTOME CONDENSATION OF PROPHASE CHROMOSOMES | 66 | 1.38e-02 | 1.75e-01 | 1.38e-01 |
| REACTOME PROCESSING AND ACTIVATION OF SUMO | 10 | 1.39e-02 | 4.49e-01 | 1.38e-01 |
| REACTOME RNA POLYMERASE I TRANSCRIPTION TERMINATION | 30 | 1.40e-02 | 2.59e-01 | 1.38e-01 |
| REACTOME REGULATION OF SIGNALING BY CBL | 22 | 1.43e-02 | 3.02e-01 | 1.41e-01 |
| REACTOME PERK REGULATES GENE EXPRESSION | 31 | 1.47e-02 | 2.53e-01 | 1.43e-01 |
| REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION | 45 | 1.47e-02 | 2.10e-01 | 1.43e-01 |
| REACTOME ASPARAGINE N LINKED GLYCOSYLATION | 299 | 1.48e-02 | 8.19e-02 | 1.43e-01 |
| REACTOME MEIOSIS | 110 | 1.50e-02 | 1.34e-01 | 1.43e-01 |
| REACTOME DEX H BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION | 7 | 1.50e-02 | -5.31e-01 | 1.43e-01 |
| REACTOME SIGNALING BY KIT IN DISEASE | 20 | 1.51e-02 | 3.14e-01 | 1.43e-01 |
| REACTOME G2 M DNA DAMAGE CHECKPOINT | 90 | 1.54e-02 | 1.48e-01 | 1.44e-01 |
| REACTOME REGULATION OF RAS BY GAPS | 66 | 1.54e-02 | 1.72e-01 | 1.44e-01 |
| REACTOME ER QUALITY CONTROL COMPARTMENT ERQC | 21 | 1.54e-02 | 3.05e-01 | 1.44e-01 |
| REACTOME SIGNALING BY SCF KIT | 42 | 1.55e-02 | 2.16e-01 | 1.44e-01 |
| REACTOME BASE EXCISION REPAIR | 87 | 1.56e-02 | 1.50e-01 | 1.44e-01 |
| REACTOME MAPK FAMILY SIGNALING CASCADES | 314 | 1.59e-02 | 7.91e-02 | 1.46e-01 |
| REACTOME FORMATION OF INCISION COMPLEX IN GG NER | 40 | 1.60e-02 | 2.20e-01 | 1.46e-01 |
| REACTOME SIGNALING BY WNT | 318 | 1.61e-02 | 7.85e-02 | 1.46e-01 |
| REACTOME DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE | 76 | 1.63e-02 | 1.59e-01 | 1.47e-01 |
| REACTOME TOLL LIKE RECEPTOR 9 TLR9 CASCADE | 100 | 1.66e-02 | 1.39e-01 | 1.49e-01 |
| REACTOME TRANSPORT OF ORGANIC ANIONS | 10 | 1.68e-02 | -4.37e-01 | 1.49e-01 |
| REACTOME PCP CE PATHWAY | 91 | 1.68e-02 | 1.45e-01 | 1.49e-01 |
| REACTOME INTERLEUKIN 1 SIGNALING | 110 | 1.69e-02 | 1.32e-01 | 1.49e-01 |
| REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING | 30 | 1.76e-02 | 2.50e-01 | 1.54e-01 |
| REACTOME RAB GERANYLGERANYLATION | 57 | 1.77e-02 | 1.82e-01 | 1.54e-01 |
| REACTOME MODULATION BY MTB OF HOST IMMUNE SYSTEM | 6 | 1.81e-02 | 5.57e-01 | 1.57e-01 |
| REACTOME FC EPSILON RECEPTOR FCERI SIGNALING | 127 | 1.82e-02 | 1.21e-01 | 1.57e-01 |
| REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | 16 | 1.88e-02 | 3.39e-01 | 1.61e-01 |
| REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS | 28 | 1.88e-02 | 2.56e-01 | 1.61e-01 |
| REACTOME TOLL LIKE RECEPTOR CASCADES | 158 | 1.89e-02 | 1.08e-01 | 1.61e-01 |
| REACTOME IRAK4 DEFICIENCY TLR2 4 | 17 | 1.90e-02 | 3.28e-01 | 1.61e-01 |
| REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | 46 | 1.93e-02 | 1.99e-01 | 1.63e-01 |
| REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS | 299 | 1.94e-02 | 7.86e-02 | 1.63e-01 |
| REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT | 236 | 1.96e-02 | -8.82e-02 | 1.64e-01 |
| REACTOME SIGNALING BY NUCLEAR RECEPTORS | 283 | 2.03e-02 | 8.01e-02 | 1.68e-01 |
| REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS | 66 | 2.04e-02 | -1.65e-01 | 1.68e-01 |
| REACTOME ADHERENS JUNCTIONS INTERACTIONS | 33 | 2.05e-02 | -2.33e-01 | 1.68e-01 |
| REACTOME DISSOLUTION OF FIBRIN CLOT | 13 | 2.11e-02 | -3.69e-01 | 1.72e-01 |
| REACTOME NEURONAL SYSTEM | 388 | 2.16e-02 | -6.79e-02 | 1.75e-01 |
| REACTOME SARS COV 1 INFECTION | 136 | 2.16e-02 | 1.14e-01 | 1.75e-01 |
| REACTOME RNA POLYMERASE III TRANSCRIPTION | 41 | 2.20e-02 | 2.07e-01 | 1.77e-01 |
| REACTOME TRNA PROCESSING | 105 | 2.25e-02 | 1.29e-01 | 1.80e-01 |
| REACTOME REGULATION OF PTEN STABILITY AND ACTIVITY | 67 | 2.28e-02 | 1.61e-01 | 1.82e-01 |
| REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | 93 | 2.32e-02 | 1.36e-01 | 1.84e-01 |
| REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM | 78 | 2.36e-02 | 1.48e-01 | 1.86e-01 |
| REACTOME DEFECTIVE EXT2 CAUSES EXOSTOSES 2 | 12 | 2.37e-02 | -3.77e-01 | 1.86e-01 |
| REACTOME TRIF MEDIATED PROGRAMMED CELL DEATH | 9 | 2.40e-02 | 4.35e-01 | 1.88e-01 |
| REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR | 79 | 2.45e-02 | 1.46e-01 | 1.90e-01 |
| REACTOME INTERLEUKIN 2 SIGNALING | 11 | 2.45e-02 | 3.92e-01 | 1.90e-01 |
| REACTOME DISEASES OF GLYCOSYLATION | 137 | 2.47e-02 | -1.11e-01 | 1.91e-01 |
| REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | 30 | 2.52e-02 | -2.36e-01 | 1.93e-01 |
| REACTOME ATTACHMENT AND ENTRY | 16 | 2.55e-02 | -3.23e-01 | 1.95e-01 |
| REACTOME KEAP1 NFE2L2 PATHWAY | 104 | 2.56e-02 | 1.27e-01 | 1.95e-01 |
| REACTOME ION TRANSPORT BY P TYPE ATPASES | 51 | 2.57e-02 | -1.81e-01 | 1.95e-01 |
| REACTOME HEMOSTASIS | 591 | 2.59e-02 | 5.36e-02 | 1.95e-01 |
| REACTOME STAT5 ACTIVATION | 7 | 2.60e-02 | 4.86e-01 | 1.95e-01 |
| REACTOME SIGNALING BY CSF1 M CSF IN MYELOID CELLS | 30 | 2.71e-02 | 2.33e-01 | 2.02e-01 |
| REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | 37 | 2.76e-02 | 2.09e-01 | 2.05e-01 |
| REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | 13 | 2.81e-02 | 3.52e-01 | 2.08e-01 |
| REACTOME COSTIMULATION BY THE CD28 FAMILY | 64 | 2.85e-02 | 1.58e-01 | 2.09e-01 |
| REACTOME COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING | 38 | 2.85e-02 | 2.05e-01 | 2.09e-01 |
| REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS | 113 | 2.87e-02 | 1.19e-01 | 2.09e-01 |
| REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX | 15 | 2.89e-02 | 3.26e-01 | 2.09e-01 |
| REACTOME MET INTERACTS WITH TNS PROTEINS | 5 | 2.90e-02 | -5.64e-01 | 2.09e-01 |
| REACTOME SUMO IS CONJUGATED TO E1 UBA2 SAE1 | 5 | 2.90e-02 | 5.64e-01 | 2.09e-01 |
| REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | 9 | 2.96e-02 | -4.19e-01 | 2.12e-01 |
| REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS | 68 | 2.97e-02 | 1.52e-01 | 2.12e-01 |
| REACTOME VISUAL PHOTOTRANSDUCTION | 93 | 3.01e-02 | -1.30e-01 | 2.12e-01 |
| REACTOME IRON UPTAKE AND TRANSPORT | 56 | 3.02e-02 | 1.67e-01 | 2.12e-01 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3 | 11 | 3.03e-02 | 3.77e-01 | 2.12e-01 |
| REACTOME KERATAN SULFATE BIOSYNTHESIS | 28 | 3.03e-02 | -2.36e-01 | 2.12e-01 |
| REACTOME PD 1 SIGNALING | 21 | 3.04e-02 | 2.73e-01 | 2.12e-01 |
| REACTOME DISEASES OF DNA REPAIR | 51 | 3.07e-02 | 1.75e-01 | 2.14e-01 |
| REACTOME NEGATIVE REGULATION OF FLT3 | 15 | 3.11e-02 | 3.21e-01 | 2.16e-01 |
| REACTOME BASE EXCISION REPAIR AP SITE FORMATION | 59 | 3.14e-02 | 1.62e-01 | 2.16e-01 |
| REACTOME NUCLEAR EVENTS MEDIATED BY NFE2L2 | 77 | 3.19e-02 | 1.41e-01 | 2.19e-01 |
| REACTOME NUCLEOTIDE EXCISION REPAIR | 107 | 3.20e-02 | 1.20e-01 | 2.19e-01 |
| REACTOME ERYTHROPOIETIN ACTIVATES STAT5 | 7 | 3.27e-02 | 4.66e-01 | 2.23e-01 |
| REACTOME STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS | 10 | 3.29e-02 | 3.90e-01 | 2.23e-01 |
| REACTOME SARS COV 2 INFECTION | 281 | 3.44e-02 | 7.33e-02 | 2.33e-01 |
| REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | 38 | 3.47e-02 | -1.98e-01 | 2.33e-01 |
| REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX | 85 | 3.48e-02 | 1.32e-01 | 2.33e-01 |
| REACTOME ANDROGEN BIOSYNTHESIS | 11 | 3.50e-02 | -3.67e-01 | 2.33e-01 |
| REACTOME MITOPHAGY | 28 | 3.51e-02 | 2.30e-01 | 2.33e-01 |
| REACTOME PROLACTIN RECEPTOR SIGNALING | 15 | 3.52e-02 | 3.14e-01 | 2.33e-01 |
| REACTOME KSRP KHSRP BINDS AND DESTABILIZES MRNA | 17 | 3.56e-02 | 2.94e-01 | 2.33e-01 |
| REACTOME COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES | 65 | 3.57e-02 | -1.51e-01 | 2.33e-01 |
| REACTOME REGULATION OF IFNG SIGNALING | 14 | 3.58e-02 | 3.24e-01 | 2.33e-01 |
| REACTOME ERYTHROPOIETIN ACTIVATES RAS | 14 | 3.58e-02 | 3.24e-01 | 2.33e-01 |
| REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER | 18 | 3.58e-02 | 2.86e-01 | 2.33e-01 |
| REACTOME TIE2 SIGNALING | 18 | 3.60e-02 | 2.85e-01 | 2.33e-01 |
| REACTOME TRANS GOLGI NETWORK VESICLE BUDDING | 67 | 3.63e-02 | 1.48e-01 | 2.33e-01 |
| REACTOME RNA POLYMERASE III CHAIN ELONGATION | 18 | 3.64e-02 | 2.85e-01 | 2.33e-01 |
| REACTOME POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION | 27 | 3.65e-02 | 2.33e-01 | 2.33e-01 |
| REACTOME SIGNALING BY ERYTHROPOIETIN | 25 | 3.68e-02 | 2.41e-01 | 2.34e-01 |
| REACTOME DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX | 83 | 3.70e-02 | 1.32e-01 | 2.35e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION BY RUNX3 | 94 | 3.72e-02 | 1.24e-01 | 2.35e-01 |
| REACTOME RHO GTPASES ACTIVATE FORMINS | 136 | 3.76e-02 | 1.03e-01 | 2.36e-01 |
| REACTOME BETA CATENIN INDEPENDENT WNT SIGNALING | 145 | 3.80e-02 | 9.98e-02 | 2.38e-01 |
| REACTOME DRUG ADME | 103 | 3.82e-02 | -1.18e-01 | 2.38e-01 |
| REACTOME DNA METHYLATION | 58 | 3.88e-02 | 1.57e-01 | 2.42e-01 |
| REACTOME COLLAGEN FORMATION | 88 | 3.95e-02 | -1.27e-01 | 2.45e-01 |
| REACTOME MITOCHONDRIAL PROTEIN IMPORT | 58 | 3.97e-02 | 1.56e-01 | 2.45e-01 |
| REACTOME DUAL INCISION IN GG NER | 39 | 4.02e-02 | 1.90e-01 | 2.47e-01 |
| REACTOME TP53 REGULATES METABOLIC GENES | 81 | 4.03e-02 | 1.32e-01 | 2.47e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS | 100 | 4.06e-02 | 1.19e-01 | 2.48e-01 |
| REACTOME BICARBONATE TRANSPORTERS | 10 | 4.12e-02 | -3.73e-01 | 2.50e-01 |
| REACTOME HATS ACETYLATE HISTONES | 129 | 4.14e-02 | 1.04e-01 | 2.51e-01 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH RAS | 9 | 4.22e-02 | 3.91e-01 | 2.54e-01 |
| REACTOME E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS | 58 | 4.23e-02 | 1.54e-01 | 2.54e-01 |
| REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION | 19 | 4.26e-02 | -2.69e-01 | 2.55e-01 |
| REACTOME O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS | 38 | 4.30e-02 | -1.90e-01 | 2.55e-01 |
| REACTOME DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15 | 8 | 4.30e-02 | -4.13e-01 | 2.55e-01 |
| REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING | 34 | 4.30e-02 | 2.01e-01 | 2.55e-01 |
| REACTOME POLO LIKE KINASE MEDIATED EVENTS | 16 | 4.42e-02 | 2.90e-01 | 2.60e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | 81 | 4.43e-02 | 1.29e-01 | 2.60e-01 |
| REACTOME PINK1 PRKN MEDIATED MITOPHAGY | 22 | 4.47e-02 | 2.47e-01 | 2.62e-01 |
| REACTOME FLT3 SIGNALING THROUGH SRC FAMILY KINASES | 6 | 4.49e-02 | 4.73e-01 | 2.63e-01 |
| REACTOME FIBRONECTIN MATRIX FORMATION | 6 | 4.51e-02 | 4.72e-01 | 2.63e-01 |
| REACTOME HDR THROUGH HOMOLOGOUS RECOMBINATION HRR | 66 | 4.52e-02 | 1.43e-01 | 2.63e-01 |
| REACTOME PREVENTION OF PHAGOSOMAL LYSOSOMAL FUSION | 9 | 4.55e-02 | 3.85e-01 | 2.63e-01 |
| REACTOME SIGNALING BY NOTCH4 | 80 | 4.61e-02 | 1.29e-01 | 2.64e-01 |
| REACTOME HCMV LATE EVENTS | 110 | 4.62e-02 | 1.10e-01 | 2.64e-01 |
| REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | 76 | 4.63e-02 | 1.32e-01 | 2.64e-01 |
| REACTOME CD22 MEDIATED BCR REGULATION | 5 | 4.63e-02 | 5.14e-01 | 2.64e-01 |
| REACTOME DISEASES OF IMMUNE SYSTEM | 29 | 4.67e-02 | 2.13e-01 | 2.65e-01 |
| REACTOME DOWNREGULATION OF ERBB2 SIGNALING | 29 | 4.77e-02 | 2.12e-01 | 2.70e-01 |
| REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION | 361 | 4.82e-02 | 6.05e-02 | 2.72e-01 |
| REACTOME ESR MEDIATED SIGNALING | 210 | 4.86e-02 | 7.90e-02 | 2.73e-01 |
| REACTOME SIGNALING BY FLT3 ITD AND TKD MUTANTS | 16 | 4.87e-02 | 2.85e-01 | 2.73e-01 |
| REACTOME TYROSINE CATABOLISM | 5 | 4.91e-02 | 5.08e-01 | 2.74e-01 |
| REACTOME MYD88 INDEPENDENT TLR4 CASCADE | 103 | 4.93e-02 | 1.12e-01 | 2.74e-01 |
| REACTOME PROTEIN UBIQUITINATION | 76 | 4.95e-02 | 1.30e-01 | 2.75e-01 |
| REACTOME SIGNAL AMPLIFICATION | 33 | 5.08e-02 | 1.96e-01 | 2.81e-01 |
| REACTOME O LINKED GLYCOSYLATION | 109 | 5.14e-02 | -1.08e-01 | 2.83e-01 |
| REACTOME ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS | 27 | 5.16e-02 | 2.16e-01 | 2.83e-01 |
| REACTOME SIGNALING BY PDGFR IN DISEASE | 20 | 5.18e-02 | 2.51e-01 | 2.84e-01 |
| REACTOME CYTOPROTECTION BY HMOX1 | 59 | 5.22e-02 | 1.46e-01 | 2.84e-01 |
| REACTOME DNA DAMAGE BYPASS | 47 | 5.24e-02 | 1.64e-01 | 2.84e-01 |
| REACTOME DAG AND IP3 SIGNALING | 40 | 5.25e-02 | -1.77e-01 | 2.84e-01 |
| REACTOME SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS | 12 | 5.25e-02 | 3.23e-01 | 2.84e-01 |
| REACTOME AMINO ACIDS REGULATE MTORC1 | 53 | 5.32e-02 | 1.54e-01 | 2.86e-01 |
| REACTOME MET ACTIVATES PTK2 SIGNALING | 30 | 5.43e-02 | -2.03e-01 | 2.90e-01 |
| REACTOME AMYLOID FIBER FORMATION | 102 | 5.44e-02 | 1.10e-01 | 2.90e-01 |
| REACTOME UNWINDING OF DNA | 12 | 5.45e-02 | 3.21e-01 | 2.90e-01 |
| REACTOME DEFECTIVE CHST6 CAUSES MCDC1 | 8 | 5.47e-02 | -3.92e-01 | 2.90e-01 |
| REACTOME NUCLEAR ENVELOPE NE REASSEMBLY | 74 | 5.54e-02 | 1.29e-01 | 2.90e-01 |
| REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE | 52 | 5.55e-02 | 1.53e-01 | 2.90e-01 |
| REACTOME KERATAN SULFATE KERATIN METABOLISM | 34 | 5.56e-02 | -1.90e-01 | 2.90e-01 |
| REACTOME HDMS DEMETHYLATE HISTONES | 40 | 5.57e-02 | 1.75e-01 | 2.90e-01 |
| REACTOME CD28 DEPENDENT VAV1 PATHWAY | 11 | 5.58e-02 | 3.33e-01 | 2.90e-01 |
| REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE | 35 | 5.59e-02 | 1.87e-01 | 2.90e-01 |
| REACTOME ION HOMEOSTASIS | 52 | 5.60e-02 | -1.53e-01 | 2.90e-01 |
| REACTOME COLLAGEN DEGRADATION | 61 | 5.60e-02 | -1.41e-01 | 2.90e-01 |
| REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL | 58 | 5.67e-02 | 1.45e-01 | 2.93e-01 |
| REACTOME HCMV EARLY EVENTS | 128 | 5.71e-02 | 9.74e-02 | 2.93e-01 |
| REACTOME ESTROGEN DEPENDENT GENE EXPRESSION | 140 | 5.71e-02 | 9.31e-02 | 2.93e-01 |
| REACTOME DAP12 INTERACTIONS | 37 | 5.75e-02 | 1.80e-01 | 2.94e-01 |
| REACTOME PRC2 METHYLATES HISTONES AND DNA | 65 | 5.76e-02 | 1.36e-01 | 2.94e-01 |
| REACTOME DAP12 SIGNALING | 27 | 5.89e-02 | 2.10e-01 | 2.99e-01 |
| REACTOME INTERLEUKIN 7 SIGNALING | 31 | 5.90e-02 | 1.96e-01 | 2.99e-01 |
| REACTOME POTENTIAL THERAPEUTICS FOR SARS | 92 | 5.91e-02 | 1.14e-01 | 2.99e-01 |
| REACTOME DISEASES OF PROGRAMMED CELL DEATH | 96 | 5.95e-02 | 1.11e-01 | 2.99e-01 |
| REACTOME ACYL CHAIN REMODELLING OF PC | 27 | 5.96e-02 | -2.09e-01 | 2.99e-01 |
| REACTOME CREB3 FACTORS ACTIVATE GENES | 8 | 5.98e-02 | 3.84e-01 | 2.99e-01 |
| REACTOME ABC TRANSPORTER DISORDERS | 76 | 6.00e-02 | 1.25e-01 | 2.99e-01 |
| REACTOME DEUBIQUITINATION | 260 | 6.08e-02 | 6.75e-02 | 3.03e-01 |
| REACTOME METALLOPROTEASE DUBS | 36 | 6.10e-02 | 1.80e-01 | 3.03e-01 |
| REACTOME PKMTS METHYLATE HISTONE LYSINES | 64 | 6.15e-02 | 1.35e-01 | 3.04e-01 |
| REACTOME SUPPRESSION OF PHAGOSOMAL MATURATION | 13 | 6.17e-02 | 2.99e-01 | 3.04e-01 |
| REACTOME PROTEIN FOLDING | 96 | 6.21e-02 | 1.10e-01 | 3.04e-01 |
| REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3 | 679 | 6.21e-02 | 4.20e-02 | 3.04e-01 |
| REACTOME INTERLEUKIN 9 SIGNALING | 7 | 6.21e-02 | 4.07e-01 | 3.04e-01 |
| REACTOME REGULATION OF IFNA IFNB SIGNALING | 23 | 6.23e-02 | 2.25e-01 | 3.04e-01 |
| REACTOME TRANSPORT OF SMALL MOLECULES | 697 | 6.31e-02 | -4.13e-02 | 3.06e-01 |
| REACTOME CELL CELL JUNCTION ORGANIZATION | 64 | 6.44e-02 | -1.34e-01 | 3.12e-01 |
| REACTOME RNA POLYMERASE III TRANSCRIPTION TERMINATION | 23 | 6.47e-02 | 2.23e-01 | 3.12e-01 |
| REACTOME NONHOMOLOGOUS END JOINING NHEJ | 64 | 6.50e-02 | 1.33e-01 | 3.13e-01 |
| REACTOME REGULATION OF TP53 ACTIVITY THROUGH METHYLATION | 19 | 6.53e-02 | 2.44e-01 | 3.13e-01 |
| REACTOME DNA DOUBLE STRAND BREAK RESPONSE | 74 | 6.61e-02 | 1.24e-01 | 3.16e-01 |
| REACTOME EXTENSION OF TELOMERES | 49 | 6.68e-02 | 1.51e-01 | 3.18e-01 |
| REACTOME PHASE 0 RAPID DEPOLARISATION | 31 | 6.68e-02 | -1.90e-01 | 3.18e-01 |
| REACTOME INTERLEUKIN 1 FAMILY SIGNALING | 146 | 6.70e-02 | 8.78e-02 | 3.18e-01 |
| REACTOME REGULATION OF KIT SIGNALING | 16 | 6.78e-02 | 2.64e-01 | 3.21e-01 |
| REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES | 11 | 6.81e-02 | 3.18e-01 | 3.21e-01 |
| REACTOME COLLAGEN CHAIN TRIMERIZATION | 42 | 6.81e-02 | -1.63e-01 | 3.21e-01 |
| REACTOME HIV LIFE CYCLE | 145 | 6.87e-02 | 8.76e-02 | 3.22e-01 |
| REACTOME RHO GTPASES ACTIVATE PKNS | 86 | 6.93e-02 | 1.13e-01 | 3.24e-01 |
| REACTOME VESICLE MEDIATED TRANSPORT | 642 | 6.94e-02 | 4.20e-02 | 3.24e-01 |
| REACTOME VXPX CARGO TARGETING TO CILIUM | 20 | 6.98e-02 | -2.34e-01 | 3.25e-01 |
| REACTOME CELL JUNCTION ORGANIZATION | 89 | 7.03e-02 | -1.11e-01 | 3.26e-01 |
| REACTOME UB SPECIFIC PROCESSING PROTEASES | 187 | 7.08e-02 | 7.66e-02 | 3.27e-01 |
| REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF | 17 | 7.09e-02 | 2.53e-01 | 3.27e-01 |
| REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | 31 | 7.10e-02 | 1.87e-01 | 3.27e-01 |
| REACTOME TRNA PROCESSING IN THE NUCLEUS | 58 | 7.12e-02 | 1.37e-01 | 3.27e-01 |
| REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | 29 | 7.18e-02 | 1.93e-01 | 3.27e-01 |
| REACTOME HCMV INFECTION | 152 | 7.23e-02 | 8.44e-02 | 3.27e-01 |
| REACTOME CRISTAE FORMATION | 27 | 7.24e-02 | 2.00e-01 | 3.27e-01 |
| REACTOME TRAFFICKING OF AMPA RECEPTORS | 29 | 7.26e-02 | -1.93e-01 | 3.27e-01 |
| REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | 66 | 7.27e-02 | 1.28e-01 | 3.27e-01 |
| REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING | 12 | 7.28e-02 | -2.99e-01 | 3.27e-01 |
| REACTOME CREATION OF C4 AND C2 ACTIVATORS | 14 | 7.28e-02 | -2.77e-01 | 3.27e-01 |
| REACTOME CDC42 GTPASE CYCLE | 144 | 7.29e-02 | -8.66e-02 | 3.27e-01 |
| REACTOME DNA STRAND ELONGATION | 31 | 7.33e-02 | 1.86e-01 | 3.28e-01 |
| REACTOME DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM | 38 | 7.35e-02 | -1.68e-01 | 3.28e-01 |
| REACTOME RNA POLYMERASE II PRE TRANSCRIPTION EVENTS | 77 | 7.41e-02 | 1.18e-01 | 3.29e-01 |
| REACTOME SIGNALING BY FLT3 FUSION PROTEINS | 19 | 7.42e-02 | 2.37e-01 | 3.29e-01 |
| REACTOME HEME BIOSYNTHESIS | 13 | 7.44e-02 | 2.86e-01 | 3.29e-01 |
| REACTOME L1CAM INTERACTIONS | 112 | 7.47e-02 | -9.75e-02 | 3.30e-01 |
| REACTOME SUMOYLATION OF TRANSCRIPTION FACTORS | 20 | 7.53e-02 | 2.30e-01 | 3.31e-01 |
| REACTOME INFECTION WITH MYCOBACTERIUM TUBERCULOSIS | 25 | 7.56e-02 | 2.05e-01 | 3.31e-01 |
| REACTOME RESOLUTION OF ABASIC SITES AP SITES | 38 | 7.57e-02 | 1.67e-01 | 3.31e-01 |
| REACTOME RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION | 22 | 7.59e-02 | -2.19e-01 | 3.31e-01 |
| REACTOME ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA | 5 | 7.62e-02 | 4.58e-01 | 3.32e-01 |
| REACTOME CLEC7A DECTIN 1 SIGNALING | 97 | 7.67e-02 | 1.04e-01 | 3.33e-01 |
| REACTOME MEMBRANE TRAFFICKING | 603 | 7.71e-02 | 4.21e-02 | 3.34e-01 |
| REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1 | 25 | 7.73e-02 | 2.04e-01 | 3.34e-01 |
| REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS | 6 | 7.74e-02 | -4.16e-01 | 3.34e-01 |
| REACTOME SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS | 74 | 7.81e-02 | 1.18e-01 | 3.35e-01 |
| REACTOME CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2 | 11 | 7.82e-02 | 3.07e-01 | 3.35e-01 |
| REACTOME REGULATION OF GENE EXPRESSION IN ENDOCRINE COMMITTED NEUROG3 PROGENITOR CELLS | 5 | 7.85e-02 | 4.54e-01 | 3.35e-01 |
| REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS | 55 | 7.86e-02 | -1.37e-01 | 3.35e-01 |
| REACTOME TOXICITY OF BOTULINUM TOXIN TYPE D BOTD | 5 | 7.91e-02 | 4.53e-01 | 3.36e-01 |
| REACTOME BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS | 10 | 7.94e-02 | 3.20e-01 | 3.36e-01 |
| REACTOME NEGATIVE REGULATION OF MAPK PATHWAY | 41 | 7.94e-02 | 1.58e-01 | 3.36e-01 |
| REACTOME TERMINATION OF TRANSLESION DNA SYNTHESIS | 32 | 7.96e-02 | 1.79e-01 | 3.36e-01 |
| REACTOME LAMININ INTERACTIONS | 28 | 8.04e-02 | -1.91e-01 | 3.39e-01 |
| REACTOME SIGNALING BY RECEPTOR TYROSINE KINASES | 507 | 8.13e-02 | 4.52e-02 | 3.41e-01 |
| REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS | 312 | 8.17e-02 | 5.73e-02 | 3.42e-01 |
| REACTOME REPRODUCTION | 136 | 8.20e-02 | 8.64e-02 | 3.43e-01 |
| REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | 296 | 8.42e-02 | 5.83e-02 | 3.51e-01 |
| REACTOME GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION | 7 | 8.48e-02 | -3.76e-01 | 3.52e-01 |
| REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE | 9 | 8.53e-02 | -3.31e-01 | 3.54e-01 |
| REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES | 18 | 8.56e-02 | -2.34e-01 | 3.54e-01 |
| REACTOME APEX1 INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | 7 | 8.58e-02 | 3.75e-01 | 3.54e-01 |
| REACTOME SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS | 16 | 8.71e-02 | 2.47e-01 | 3.58e-01 |
| REACTOME TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7 | 12 | 8.73e-02 | 2.85e-01 | 3.58e-01 |
| REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS | 5 | 8.74e-02 | -4.41e-01 | 3.58e-01 |
| REACTOME PREDNISONE ADME | 10 | 8.86e-02 | -3.11e-01 | 3.62e-01 |
| REACTOME FRS MEDIATED FGFR2 SIGNALING | 24 | 8.88e-02 | 2.01e-01 | 3.62e-01 |
| REACTOME DISEASES OF MISMATCH REPAIR MMR | 5 | 9.02e-02 | 4.38e-01 | 3.66e-01 |
| REACTOME RUNX2 REGULATES BONE DEVELOPMENT | 29 | 9.02e-02 | -1.82e-01 | 3.66e-01 |
| REACTOME DEADENYLATION OF MRNA | 25 | 9.09e-02 | 1.95e-01 | 3.67e-01 |
| REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA | 28 | 9.11e-02 | 1.84e-01 | 3.67e-01 |
| REACTOME RAB REGULATION OF TRAFFICKING | 110 | 9.12e-02 | 9.32e-02 | 3.67e-01 |
| REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | 22 | 9.13e-02 | 2.08e-01 | 3.67e-01 |
| REACTOME TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS | 26 | 9.26e-02 | 1.91e-01 | 3.70e-01 |
| REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | 14 | 9.27e-02 | 2.60e-01 | 3.70e-01 |
| REACTOME MITOTIC PROMETAPHASE | 194 | 9.34e-02 | 6.99e-02 | 3.72e-01 |
| REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | 160 | 9.49e-02 | 7.65e-02 | 3.77e-01 |
| REACTOME CRMPS IN SEMA3A SIGNALING | 15 | 9.51e-02 | -2.49e-01 | 3.77e-01 |
| REACTOME MISMATCH REPAIR | 15 | 9.54e-02 | 2.49e-01 | 3.77e-01 |
| REACTOME MUSCLE CONTRACTION | 197 | 9.57e-02 | -6.88e-02 | 3.78e-01 |
| REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A | 26 | 9.65e-02 | 1.88e-01 | 3.79e-01 |
| REACTOME INDUCTION OF CELL CELL FUSION | 12 | 9.65e-02 | -2.77e-01 | 3.79e-01 |
| REACTOME OPSINS | 7 | 9.74e-02 | -3.62e-01 | 3.82e-01 |
| REACTOME SARS COV 2 ACTIVATES MODULATES INNATE AND ADAPTIVE IMMUNE RESPONSES | 118 | 9.84e-02 | 8.81e-02 | 3.85e-01 |
| REACTOME RHOBTB2 GTPASE CYCLE | 22 | 9.87e-02 | 2.03e-01 | 3.85e-01 |
| REACTOME CONDENSATION OF PROMETAPHASE CHROMOSOMES | 11 | 9.92e-02 | 2.87e-01 | 3.86e-01 |
| REACTOME MITOTIC PROPHASE | 134 | 1.00e-01 | 8.22e-02 | 3.90e-01 |
| REACTOME C TYPE LECTIN RECEPTORS CLRS | 136 | 1.01e-01 | 8.14e-02 | 3.91e-01 |
| REACTOME TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA | 17 | 1.01e-01 | 2.30e-01 | 3.91e-01 |
| REACTOME TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS | 52 | 1.03e-01 | 1.31e-01 | 3.96e-01 |
| REACTOME AUTOPHAGY | 144 | 1.03e-01 | 7.87e-02 | 3.96e-01 |
| REACTOME HDR THROUGH MMEJ ALT NHEJ | 12 | 1.03e-01 | 2.72e-01 | 3.96e-01 |
| REACTOME SIGNALING BY ALK IN CANCER | 53 | 1.04e-01 | 1.29e-01 | 3.96e-01 |
| REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K | 12 | 1.04e-01 | 2.71e-01 | 3.97e-01 |
| REACTOME COPII MEDIATED VESICLE TRANSPORT | 66 | 1.04e-01 | 1.16e-01 | 3.98e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES | 61 | 1.05e-01 | 1.20e-01 | 3.98e-01 |
| REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES | 10 | 1.05e-01 | 2.96e-01 | 3.98e-01 |
| REACTOME SEROTONIN RECEPTORS | 11 | 1.06e-01 | 2.82e-01 | 3.98e-01 |
| REACTOME FGFR2B LIGAND BINDING AND ACTIVATION | 10 | 1.06e-01 | 2.95e-01 | 3.98e-01 |
| REACTOME FOLDING OF ACTIN BY CCT TRIC | 10 | 1.06e-01 | 2.95e-01 | 3.98e-01 |
| REACTOME TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE | 39 | 1.07e-01 | 1.49e-01 | 3.98e-01 |
| REACTOME SODIUM CALCIUM EXCHANGERS | 11 | 1.07e-01 | -2.81e-01 | 3.98e-01 |
| REACTOME MISCELLANEOUS TRANSPORT AND BINDING EVENTS | 24 | 1.07e-01 | -1.90e-01 | 3.98e-01 |
| REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | 62 | 1.07e-01 | 1.18e-01 | 3.98e-01 |
| REACTOME COMPLEX I BIOGENESIS | 49 | 1.07e-01 | 1.33e-01 | 3.98e-01 |
| REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | 99 | 1.07e-01 | 9.37e-02 | 3.98e-01 |
| REACTOME INTERLEUKIN 36 PATHWAY | 7 | 1.07e-01 | -3.51e-01 | 3.98e-01 |
| REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER | 28 | 1.08e-01 | 1.76e-01 | 3.99e-01 |
| REACTOME SELECTIVE AUTOPHAGY | 79 | 1.08e-01 | 1.05e-01 | 4.00e-01 |
| REACTOME MITOTIC G2 G2 M PHASES | 194 | 1.09e-01 | 6.67e-02 | 4.01e-01 |
| REACTOME PHASE 4 RESTING MEMBRANE POTENTIAL | 19 | 1.09e-01 | -2.12e-01 | 4.01e-01 |
| REACTOME NERVOUS SYSTEM DEVELOPMENT | 552 | 1.10e-01 | 3.98e-02 | 4.03e-01 |
| REACTOME SURFACTANT METABOLISM | 28 | 1.11e-01 | 1.74e-01 | 4.03e-01 |
| REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM | 50 | 1.11e-01 | -1.30e-01 | 4.03e-01 |
| REACTOME HYALURONAN METABOLISM | 17 | 1.11e-01 | 2.23e-01 | 4.03e-01 |
| REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | 55 | 1.11e-01 | 1.24e-01 | 4.03e-01 |
| REACTOME FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS | 8 | 1.11e-01 | -3.25e-01 | 4.04e-01 |
| REACTOME RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX | 29 | 1.12e-01 | 1.71e-01 | 4.04e-01 |
| REACTOME NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION | 193 | 1.13e-01 | -6.62e-02 | 4.06e-01 |
| REACTOME INTERFERON SIGNALING | 193 | 1.13e-01 | 6.61e-02 | 4.06e-01 |
| REACTOME TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER | 76 | 1.13e-01 | 1.05e-01 | 4.06e-01 |
| REACTOME DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA | 77 | 1.13e-01 | 1.04e-01 | 4.06e-01 |
| REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION | 59 | 1.14e-01 | 1.19e-01 | 4.08e-01 |
| REACTOME REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO | 10 | 1.15e-01 | -2.88e-01 | 4.08e-01 |
| REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | 16 | 1.15e-01 | 2.28e-01 | 4.08e-01 |
| REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE | 63 | 1.15e-01 | 1.15e-01 | 4.09e-01 |
| REACTOME PI 3K CASCADE FGFR2 | 22 | 1.17e-01 | 1.93e-01 | 4.13e-01 |
| REACTOME CYCLIN D ASSOCIATED EVENTS IN G1 | 46 | 1.18e-01 | 1.33e-01 | 4.18e-01 |
| REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | 22 | 1.20e-01 | 1.91e-01 | 4.25e-01 |
| REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | 17 | 1.21e-01 | 2.17e-01 | 4.27e-01 |
| REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | 10 | 1.22e-01 | -2.82e-01 | 4.29e-01 |
| REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | 11 | 1.22e-01 | 2.69e-01 | 4.29e-01 |
| REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | 118 | 1.22e-01 | -8.23e-02 | 4.29e-01 |
| REACTOME INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION | 21 | 1.24e-01 | 1.94e-01 | 4.32e-01 |
| REACTOME RHOQ GTPASE CYCLE | 57 | 1.24e-01 | -1.18e-01 | 4.34e-01 |
| REACTOME GENE SILENCING BY RNA | 133 | 1.25e-01 | 7.71e-02 | 4.34e-01 |
| REACTOME RECYCLING OF EIF2 GDP | 7 | 1.25e-01 | 3.35e-01 | 4.34e-01 |
| REACTOME ORGANIC ANION TRANSPORTERS | 10 | 1.26e-01 | 2.80e-01 | 4.34e-01 |
| REACTOME PEXOPHAGY | 11 | 1.26e-01 | 2.67e-01 | 4.34e-01 |
| REACTOME TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS | 82 | 1.26e-01 | -9.78e-02 | 4.34e-01 |
| REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | 20 | 1.26e-01 | 1.98e-01 | 4.34e-01 |
| REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND | 21 | 1.27e-01 | 1.93e-01 | 4.35e-01 |
| REACTOME KILLING MECHANISMS | 11 | 1.27e-01 | 2.66e-01 | 4.35e-01 |
| REACTOME POTASSIUM CHANNELS | 102 | 1.30e-01 | -8.68e-02 | 4.44e-01 |
| REACTOME PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING | 11 | 1.30e-01 | -2.64e-01 | 4.44e-01 |
| REACTOME SARS COV 2 MODULATES AUTOPHAGY | 11 | 1.31e-01 | 2.63e-01 | 4.47e-01 |
| REACTOME INTERLEUKIN 15 SIGNALING | 13 | 1.32e-01 | 2.41e-01 | 4.50e-01 |
| REACTOME DISEASES OF METABOLISM | 237 | 1.33e-01 | -5.66e-02 | 4.53e-01 |
| REACTOME INTERLEUKIN 1 PROCESSING | 9 | 1.34e-01 | -2.88e-01 | 4.54e-01 |
| REACTOME GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER | 25 | 1.35e-01 | 1.73e-01 | 4.55e-01 |
| REACTOME VITAMINS | 6 | 1.35e-01 | 3.52e-01 | 4.56e-01 |
| REACTOME GLUCURONIDATION | 23 | 1.37e-01 | -1.79e-01 | 4.58e-01 |
| REACTOME FGFR2 LIGAND BINDING AND ACTIVATION | 19 | 1.37e-01 | 1.97e-01 | 4.58e-01 |
| REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | 10 | 1.38e-01 | -2.71e-01 | 4.58e-01 |
| REACTOME NEDDYLATION | 235 | 1.38e-01 | 5.62e-02 | 4.58e-01 |
| REACTOME PROSTANOID LIGAND RECEPTORS | 9 | 1.38e-01 | 2.86e-01 | 4.58e-01 |
| REACTOME TBC RABGAPS | 40 | 1.39e-01 | 1.35e-01 | 4.58e-01 |
| REACTOME FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES | 29 | 1.39e-01 | -1.59e-01 | 4.58e-01 |
| REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET | 8 | 1.39e-01 | -3.02e-01 | 4.58e-01 |
| REACTOME CHOLINE CATABOLISM | 6 | 1.39e-01 | -3.49e-01 | 4.58e-01 |
| REACTOME RND2 GTPASE CYCLE | 42 | 1.39e-01 | -1.32e-01 | 4.58e-01 |
| REACTOME REGULATION OF PTEN GENE TRANSCRIPTION | 59 | 1.39e-01 | 1.11e-01 | 4.58e-01 |
| REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX | 91 | 1.39e-01 | 8.97e-02 | 4.58e-01 |
| REACTOME MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS | 7 | 1.40e-01 | 3.22e-01 | 4.58e-01 |
| REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | 51 | 1.40e-01 | 1.20e-01 | 4.58e-01 |
| REACTOME DISEASES OF BASE EXCISION REPAIR | 5 | 1.40e-01 | 3.81e-01 | 4.58e-01 |
| REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR2 | 29 | 1.40e-01 | 1.58e-01 | 4.58e-01 |
| REACTOME MRNA SPLICING MINOR PATHWAY | 49 | 1.41e-01 | 1.22e-01 | 4.58e-01 |
| REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC | 198 | 1.42e-01 | 6.06e-02 | 4.61e-01 |
| REACTOME INTERLEUKIN 12 FAMILY SIGNALING | 53 | 1.43e-01 | 1.16e-01 | 4.64e-01 |
| REACTOME CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT | 19 | 1.43e-01 | 1.94e-01 | 4.64e-01 |
| REACTOME RESPONSE OF MTB TO PHAGOCYTOSIS | 22 | 1.44e-01 | 1.80e-01 | 4.65e-01 |
| REACTOME INTERLEUKIN 27 SIGNALING | 11 | 1.45e-01 | 2.54e-01 | 4.65e-01 |
| REACTOME DUAL INCISION IN TC NER | 63 | 1.45e-01 | 1.06e-01 | 4.65e-01 |
| REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL | 15 | 1.45e-01 | -2.17e-01 | 4.65e-01 |
| REACTOME NRAGE SIGNALS DEATH THROUGH JNK | 53 | 1.45e-01 | -1.16e-01 | 4.65e-01 |
| REACTOME MET ACTIVATES RAS SIGNALING | 11 | 1.45e-01 | 2.54e-01 | 4.65e-01 |
| REACTOME PEPTIDE LIGAND BINDING RECEPTORS | 188 | 1.46e-01 | 6.15e-02 | 4.66e-01 |
| REACTOME TRANSCRIPTION OF THE HIV GENOME | 66 | 1.47e-01 | 1.03e-01 | 4.69e-01 |
| REACTOME GPCR LIGAND BINDING | 444 | 1.48e-01 | 4.01e-02 | 4.71e-01 |
| REACTOME ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES | 59 | 1.49e-01 | -1.09e-01 | 4.72e-01 |
| REACTOME ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS | 17 | 1.49e-01 | 2.02e-01 | 4.72e-01 |
| REACTOME ACTIVATION OF BH3 ONLY PROTEINS | 30 | 1.49e-01 | 1.52e-01 | 4.72e-01 |
| REACTOME PKA ACTIVATION IN GLUCAGON SIGNALLING | 17 | 1.50e-01 | -2.02e-01 | 4.73e-01 |
| REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES | 39 | 1.50e-01 | 1.33e-01 | 4.73e-01 |
| REACTOME SUMO IS PROTEOLYTICALLY PROCESSED | 6 | 1.50e-01 | 3.39e-01 | 4.73e-01 |
| REACTOME NICOTINAMIDE SALVAGING | 19 | 1.51e-01 | -1.90e-01 | 4.74e-01 |
| REACTOME FORMATION OF TC NER PRE INCISION COMPLEX | 51 | 1.51e-01 | 1.16e-01 | 4.75e-01 |
| REACTOME CARNITINE METABOLISM | 13 | 1.52e-01 | -2.29e-01 | 4.75e-01 |
| REACTOME CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA | 63 | 1.52e-01 | 1.04e-01 | 4.75e-01 |
| REACTOME DEFECTIVE CHST14 CAUSES EDS MUSCULOCONTRACTURAL TYPE | 7 | 1.52e-01 | 3.12e-01 | 4.75e-01 |
| REACTOME HEDGEHOG ON STATE | 85 | 1.53e-01 | 8.97e-02 | 4.75e-01 |
| REACTOME DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B | 7 | 1.54e-01 | 3.11e-01 | 4.79e-01 |
| REACTOME GLYCOSAMINOGLYCAN METABOLISM | 118 | 1.56e-01 | -7.56e-02 | 4.84e-01 |
| REACTOME INTERLEUKIN 21 SIGNALING | 9 | 1.57e-01 | 2.73e-01 | 4.85e-01 |
| REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX | 19 | 1.57e-01 | 1.87e-01 | 4.86e-01 |
| REACTOME PROCESSING OF INTRONLESS PRE MRNAS | 19 | 1.58e-01 | 1.87e-01 | 4.87e-01 |
| REACTOME FGFRL1 MODULATION OF FGFR1 SIGNALING | 13 | 1.58e-01 | 2.26e-01 | 4.87e-01 |
| REACTOME INITIATION OF NUCLEAR ENVELOPE NE REFORMATION | 18 | 1.59e-01 | 1.92e-01 | 4.87e-01 |
| REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | 122 | 1.60e-01 | 7.37e-02 | 4.87e-01 |
| REACTOME REGULATION OF SIGNALING BY NODAL | 9 | 1.60e-01 | -2.71e-01 | 4.87e-01 |
| REACTOME FCERI MEDIATED MAPK ACTIVATION | 32 | 1.60e-01 | 1.44e-01 | 4.87e-01 |
| REACTOME HYALURONAN UPTAKE AND DEGRADATION | 12 | 1.60e-01 | 2.34e-01 | 4.87e-01 |
| REACTOME METABOLISM OF VITAMINS AND COFACTORS | 185 | 1.61e-01 | -5.98e-02 | 4.89e-01 |
| REACTOME FRS MEDIATED FGFR3 SIGNALING | 19 | 1.62e-01 | 1.85e-01 | 4.91e-01 |
| REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES | 34 | 1.62e-01 | 1.38e-01 | 4.92e-01 |
| REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | 54 | 1.63e-01 | 1.10e-01 | 4.92e-01 |
| REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | 111 | 1.65e-01 | 7.62e-02 | 4.98e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES | 49 | 1.65e-01 | 1.15e-01 | 4.98e-01 |
| REACTOME FLT3 SIGNALING BY CBL MUTANTS | 7 | 1.66e-01 | 3.03e-01 | 4.98e-01 |
| REACTOME DEFECTIVE B4GALT1 CAUSES B4GALT1 CDG CDG 2D | 8 | 1.66e-01 | -2.83e-01 | 4.98e-01 |
| REACTOME TRNA MODIFICATION IN THE MITOCHONDRION | 8 | 1.67e-01 | 2.82e-01 | 4.99e-01 |
| REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR | 24 | 1.67e-01 | 1.63e-01 | 5.00e-01 |
| REACTOME SIALIC ACID METABOLISM | 33 | 1.68e-01 | 1.39e-01 | 5.00e-01 |
| REACTOME RHOBTB GTPASE CYCLE | 34 | 1.68e-01 | 1.37e-01 | 5.01e-01 |
| REACTOME SIGNALING BY EGFR IN CANCER | 25 | 1.68e-01 | 1.59e-01 | 5.01e-01 |
| REACTOME LIPID PARTICLE ORGANIZATION | 6 | 1.69e-01 | 3.24e-01 | 5.01e-01 |
| REACTOME FASL CD95L SIGNALING | 5 | 1.69e-01 | 3.55e-01 | 5.01e-01 |
| REACTOME FRS MEDIATED FGFR1 SIGNALING | 23 | 1.70e-01 | 1.65e-01 | 5.02e-01 |
| REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES | 78 | 1.71e-01 | -8.97e-02 | 5.04e-01 |
| REACTOME TERMINAL PATHWAY OF COMPLEMENT | 8 | 1.71e-01 | -2.79e-01 | 5.05e-01 |
| REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS | 8 | 1.72e-01 | 2.79e-01 | 5.05e-01 |
| REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER | 77 | 1.72e-01 | 9.01e-02 | 5.05e-01 |
| REACTOME SIGNALING BY NODAL | 20 | 1.74e-01 | -1.75e-01 | 5.11e-01 |
| REACTOME REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS | 11 | 1.75e-01 | -2.36e-01 | 5.12e-01 |
| REACTOME EICOSANOID LIGAND BINDING RECEPTORS | 14 | 1.76e-01 | 2.09e-01 | 5.13e-01 |
| REACTOME SIGNALING BY NTRKS | 132 | 1.76e-01 | 6.82e-02 | 5.13e-01 |
| REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY | 26 | 1.77e-01 | -1.53e-01 | 5.13e-01 |
| REACTOME CD28 CO STIMULATION | 32 | 1.77e-01 | 1.38e-01 | 5.13e-01 |
| REACTOME EARLY PHASE OF HIV LIFE CYCLE | 14 | 1.77e-01 | 2.08e-01 | 5.13e-01 |
| REACTOME SIGNALING BY RETINOIC ACID | 41 | 1.77e-01 | 1.22e-01 | 5.13e-01 |
| REACTOME SIGNALING BY LEPTIN | 11 | 1.78e-01 | 2.35e-01 | 5.13e-01 |
| REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | 20 | 1.79e-01 | 1.74e-01 | 5.15e-01 |
| REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12 | 22 | 1.79e-01 | 1.66e-01 | 5.15e-01 |
| REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES | 255 | 1.79e-01 | -4.89e-02 | 5.15e-01 |
| REACTOME NEGATIVE REGULATION OF MET ACTIVITY | 20 | 1.81e-01 | 1.73e-01 | 5.18e-01 |
| REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | 80 | 1.81e-01 | 8.66e-02 | 5.18e-01 |
| REACTOME INACTIVATION OF CDC42 AND RAC1 | 8 | 1.81e-01 | -2.73e-01 | 5.18e-01 |
| REACTOME INTERLEUKIN 35 SIGNALLING | 12 | 1.81e-01 | 2.23e-01 | 5.18e-01 |
| REACTOME DIGESTION AND ABSORPTION | 22 | 1.82e-01 | -1.64e-01 | 5.19e-01 |
| REACTOME BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA | 17 | 1.83e-01 | 1.87e-01 | 5.20e-01 |
| REACTOME VITAMIN D CALCIFEROL METABOLISM | 12 | 1.83e-01 | 2.22e-01 | 5.20e-01 |
| REACTOME DRUG MEDIATED INHIBITION OF CDK4 CDK6 ACTIVITY | 5 | 1.84e-01 | 3.43e-01 | 5.21e-01 |
| REACTOME TELOMERE EXTENSION BY TELOMERASE | 22 | 1.85e-01 | 1.63e-01 | 5.22e-01 |
| REACTOME GENERATION OF SECOND MESSENGER MOLECULES | 30 | 1.85e-01 | 1.40e-01 | 5.23e-01 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH PI3K | 7 | 1.85e-01 | 2.89e-01 | 5.23e-01 |
| REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS | 15 | 1.87e-01 | 1.97e-01 | 5.25e-01 |
| REACTOME AZATHIOPRINE ADME | 22 | 1.87e-01 | -1.63e-01 | 5.25e-01 |
| REACTOME GROWTH HORMONE RECEPTOR SIGNALING | 24 | 1.87e-01 | 1.56e-01 | 5.25e-01 |
| REACTOME INTERLEUKIN 17 SIGNALING | 66 | 1.87e-01 | 9.38e-02 | 5.25e-01 |
| REACTOME CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND | 16 | 1.88e-01 | 1.90e-01 | 5.25e-01 |
| REACTOME METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION | 15 | 1.88e-01 | -1.96e-01 | 5.25e-01 |
| REACTOME TRYPTOPHAN CATABOLISM | 14 | 1.88e-01 | -2.03e-01 | 5.25e-01 |
| REACTOME DIGESTION OF DIETARY LIPID | 7 | 1.89e-01 | -2.87e-01 | 5.25e-01 |
| REACTOME SNRNP ASSEMBLY | 53 | 1.89e-01 | 1.04e-01 | 5.25e-01 |
| REACTOME CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION | 11 | 1.90e-01 | -2.28e-01 | 5.26e-01 |
| REACTOME NECTIN NECL TRANS HETERODIMERIZATION | 7 | 1.90e-01 | -2.86e-01 | 5.26e-01 |
| REACTOME NGF INDEPENDANT TRKA ACTIVATION | 5 | 1.90e-01 | 3.38e-01 | 5.26e-01 |
| REACTOME GAP JUNCTION ASSEMBLY | 36 | 1.92e-01 | -1.26e-01 | 5.29e-01 |
| REACTOME TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX | 10 | 1.94e-01 | 2.37e-01 | 5.35e-01 |
| REACTOME SUMOYLATION OF INTRACELLULAR RECEPTORS | 29 | 1.95e-01 | 1.39e-01 | 5.35e-01 |
| REACTOME CIRCADIAN CLOCK | 68 | 1.95e-01 | 9.08e-02 | 5.35e-01 |
| REACTOME BIOTIN TRANSPORT AND METABOLISM | 10 | 1.96e-01 | -2.36e-01 | 5.35e-01 |
| REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION | 250 | 1.96e-01 | 4.75e-02 | 5.35e-01 |
| REACTOME ER TO GOLGI ANTEROGRADE TRANSPORT | 152 | 1.96e-01 | 6.08e-02 | 5.35e-01 |
| REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX | 57 | 1.99e-01 | 9.84e-02 | 5.42e-01 |
| REACTOME TRANSLESION SYNTHESIS BY POLK | 17 | 1.99e-01 | 1.80e-01 | 5.42e-01 |
| REACTOME LIPOPHAGY | 9 | 2.01e-01 | 2.46e-01 | 5.45e-01 |
| REACTOME SYNTHESIS OF PG | 8 | 2.01e-01 | 2.61e-01 | 5.45e-01 |
| REACTOME ACTIVATION OF MATRIX METALLOPROTEINASES | 30 | 2.01e-01 | -1.35e-01 | 5.45e-01 |
| REACTOME TNF SIGNALING | 54 | 2.01e-01 | 1.01e-01 | 5.45e-01 |
| REACTOME DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE | 17 | 2.02e-01 | -1.79e-01 | 5.45e-01 |
| REACTOME CA DEPENDENT EVENTS | 36 | 2.03e-01 | -1.23e-01 | 5.45e-01 |
| REACTOME MYOCLONIC EPILEPSY OF LAFORA | 9 | 2.03e-01 | 2.45e-01 | 5.45e-01 |
| REACTOME METHYLATION | 14 | 2.03e-01 | -1.97e-01 | 5.45e-01 |
| REACTOME LYSOSPHINGOLIPID AND LPA RECEPTORS | 14 | 2.03e-01 | 1.97e-01 | 5.45e-01 |
| REACTOME MET ACTIVATES RAP1 AND RAC1 | 11 | 2.04e-01 | -2.21e-01 | 5.48e-01 |
| REACTOME IRAK1 RECRUITS IKK COMPLEX | 12 | 2.06e-01 | 2.11e-01 | 5.50e-01 |
| REACTOME PEROXISOMAL LIPID METABOLISM | 28 | 2.07e-01 | 1.38e-01 | 5.53e-01 |
| REACTOME HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE | 43 | 2.07e-01 | 1.11e-01 | 5.53e-01 |
| REACTOME STRIATED MUSCLE CONTRACTION | 35 | 2.08e-01 | 1.23e-01 | 5.54e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN | 21 | 2.09e-01 | 1.58e-01 | 5.54e-01 |
| REACTOME HORMONE LIGAND BINDING RECEPTORS | 12 | 2.09e-01 | -2.10e-01 | 5.54e-01 |
| REACTOME DEVELOPMENTAL BIOLOGY | 1115 | 2.10e-01 | 2.23e-02 | 5.55e-01 |
| REACTOME PEPTIDE HORMONE BIOSYNTHESIS | 13 | 2.10e-01 | 2.01e-01 | 5.56e-01 |
| REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | 91 | 2.11e-01 | -7.59e-02 | 5.57e-01 |
| REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING | 33 | 2.12e-01 | 1.26e-01 | 5.58e-01 |
| REACTOME GAB1 SIGNALOSOME | 17 | 2.12e-01 | 1.75e-01 | 5.59e-01 |
| REACTOME AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS | 9 | 2.13e-01 | -2.40e-01 | 5.59e-01 |
| REACTOME PI 3K CASCADE FGFR3 | 17 | 2.14e-01 | 1.74e-01 | 5.61e-01 |
| REACTOME KERATAN SULFATE DEGRADATION | 13 | 2.15e-01 | -1.99e-01 | 5.61e-01 |
| REACTOME ACYL CHAIN REMODELLING OF PS | 22 | 2.15e-01 | -1.53e-01 | 5.61e-01 |
| REACTOME NCAM1 INTERACTIONS | 41 | 2.15e-01 | -1.12e-01 | 5.61e-01 |
| REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS | 13 | 2.15e-01 | 1.98e-01 | 5.61e-01 |
| REACTOME INTERFERON GAMMA SIGNALING | 88 | 2.16e-01 | 7.63e-02 | 5.62e-01 |
| REACTOME GLUTAMATE AND GLUTAMINE METABOLISM | 13 | 2.17e-01 | 1.98e-01 | 5.64e-01 |
| REACTOME METABOLISM OF INGESTED SEMET SEC MESEC INTO H2SE | 7 | 2.18e-01 | -2.69e-01 | 5.65e-01 |
| REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | 24 | 2.18e-01 | -1.45e-01 | 5.65e-01 |
| REACTOME UPTAKE OF DIETARY COBALAMINS INTO ENTEROCYTES | 9 | 2.19e-01 | -2.37e-01 | 5.66e-01 |
| REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION | 8 | 2.20e-01 | -2.51e-01 | 5.66e-01 |
| REACTOME XENOBIOTICS | 22 | 2.20e-01 | -1.51e-01 | 5.66e-01 |
| REACTOME DIGESTION | 17 | 2.21e-01 | -1.72e-01 | 5.66e-01 |
| REACTOME GOLGI TO ER RETROGRADE TRANSPORT | 132 | 2.21e-01 | 6.17e-02 | 5.66e-01 |
| REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA | 11 | 2.21e-01 | -2.13e-01 | 5.66e-01 |
| REACTOME PI 3K CASCADE FGFR1 | 21 | 2.21e-01 | 1.54e-01 | 5.66e-01 |
| REACTOME MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS | 13 | 2.22e-01 | 1.96e-01 | 5.66e-01 |
| REACTOME SIGNALING BY MST1 | 5 | 2.22e-01 | -3.15e-01 | 5.66e-01 |
| REACTOME PLATELET AGGREGATION PLUG FORMATION | 39 | 2.22e-01 | 1.13e-01 | 5.66e-01 |
| REACTOME ENOS ACTIVATION | 11 | 2.23e-01 | -2.12e-01 | 5.66e-01 |
| REACTOME G PROTEIN ACTIVATION | 24 | 2.23e-01 | 1.44e-01 | 5.66e-01 |
| REACTOME SHC MEDIATED CASCADE FGFR3 | 17 | 2.24e-01 | 1.70e-01 | 5.69e-01 |
| REACTOME HS GAG DEGRADATION | 19 | 2.25e-01 | -1.61e-01 | 5.69e-01 |
| REACTOME HIV TRANSCRIPTION INITIATION | 43 | 2.26e-01 | 1.07e-01 | 5.69e-01 |
| REACTOME MHC CLASS II ANTIGEN PRESENTATION | 121 | 2.26e-01 | 6.37e-02 | 5.69e-01 |
| REACTOME DISINHIBITION OF SNARE FORMATION | 5 | 2.27e-01 | 3.12e-01 | 5.69e-01 |
| REACTOME SIGNALLING TO RAS | 20 | 2.27e-01 | 1.56e-01 | 5.69e-01 |
| REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | 36 | 2.27e-01 | 1.16e-01 | 5.69e-01 |
| REACTOME INTERLEUKIN 12 SIGNALING | 43 | 2.27e-01 | 1.07e-01 | 5.69e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN | 13 | 2.27e-01 | 1.94e-01 | 5.69e-01 |
| REACTOME MAP2K AND MAPK ACTIVATION | 38 | 2.27e-01 | 1.13e-01 | 5.69e-01 |
| REACTOME REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR | 11 | 2.28e-01 | 2.10e-01 | 5.70e-01 |
| REACTOME PI3K AKT SIGNALING IN CANCER | 103 | 2.29e-01 | 6.86e-02 | 5.71e-01 |
| REACTOME DISEASES OF MITOTIC CELL CYCLE | 37 | 2.29e-01 | 1.14e-01 | 5.72e-01 |
| REACTOME DNA DAMAGE RECOGNITION IN GG NER | 36 | 2.30e-01 | 1.16e-01 | 5.73e-01 |
| REACTOME SHC MEDIATED CASCADE FGFR1 | 21 | 2.31e-01 | 1.51e-01 | 5.73e-01 |
| REACTOME REACTIONS SPECIFIC TO THE COMPLEX N GLYCAN SYNTHESIS PATHWAY | 10 | 2.32e-01 | -2.18e-01 | 5.74e-01 |
| REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES | 29 | 2.32e-01 | 1.28e-01 | 5.75e-01 |
| REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING | 25 | 2.35e-01 | 1.37e-01 | 5.80e-01 |
| REACTOME ARYL HYDROCARBON RECEPTOR SIGNALLING | 6 | 2.35e-01 | 2.80e-01 | 5.81e-01 |
| REACTOME TRIGLYCERIDE CATABOLISM | 23 | 2.37e-01 | 1.43e-01 | 5.83e-01 |
| REACTOME G0 AND EARLY G1 | 27 | 2.37e-01 | 1.32e-01 | 5.83e-01 |
| REACTOME CS DS DEGRADATION | 12 | 2.38e-01 | 1.97e-01 | 5.86e-01 |
| REACTOME SMAC XIAP REGULATED APOPTOTIC RESPONSE | 7 | 2.39e-01 | 2.57e-01 | 5.87e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION BY E2F6 | 32 | 2.41e-01 | 1.20e-01 | 5.89e-01 |
| REACTOME SLC TRANSPORTER DISORDERS | 94 | 2.41e-01 | -7.00e-02 | 5.89e-01 |
| REACTOME SIGNALING BY FGFR2 | 72 | 2.41e-01 | 7.99e-02 | 5.89e-01 |
| REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1 | 31 | 2.42e-01 | 1.21e-01 | 5.89e-01 |
| REACTOME RET SIGNALING | 40 | 2.42e-01 | 1.07e-01 | 5.89e-01 |
| REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR3 | 24 | 2.44e-01 | 1.37e-01 | 5.93e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION BY MECP2 | 60 | 2.44e-01 | 8.69e-02 | 5.93e-01 |
| REACTOME KETONE BODY METABOLISM | 9 | 2.46e-01 | -2.23e-01 | 5.96e-01 |
| REACTOME CALCITONIN LIKE LIGAND RECEPTORS | 10 | 2.46e-01 | 2.12e-01 | 5.96e-01 |
| REACTOME APOPTOTIC EXECUTION PHASE | 49 | 2.47e-01 | 9.57e-02 | 5.96e-01 |
| REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES | 77 | 2.48e-01 | -7.61e-02 | 6.00e-01 |
| REACTOME RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA | 27 | 2.49e-01 | 1.28e-01 | 6.01e-01 |
| REACTOME REGULATION OF BACH1 ACTIVITY | 11 | 2.50e-01 | 2.00e-01 | 6.03e-01 |
| REACTOME COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING | 32 | 2.51e-01 | 1.17e-01 | 6.03e-01 |
| REACTOME CLATHRIN MEDIATED ENDOCYTOSIS | 139 | 2.52e-01 | 5.63e-02 | 6.03e-01 |
| REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS | 16 | 2.53e-01 | -1.65e-01 | 6.03e-01 |
| REACTOME DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1 | 9 | 2.53e-01 | 2.20e-01 | 6.03e-01 |
| REACTOME COMPLEMENT CASCADE | 54 | 2.53e-01 | -8.98e-02 | 6.03e-01 |
| REACTOME NETRIN 1 SIGNALING | 49 | 2.54e-01 | -9.42e-02 | 6.03e-01 |
| REACTOME G ALPHA 12 13 SIGNALLING EVENTS | 74 | 2.54e-01 | -7.67e-02 | 6.03e-01 |
| REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | 14 | 2.55e-01 | -1.76e-01 | 6.03e-01 |
| REACTOME PLASMA LIPOPROTEIN CLEARANCE | 37 | 2.55e-01 | 1.08e-01 | 6.03e-01 |
| REACTOME RND3 GTPASE CYCLE | 41 | 2.55e-01 | -1.03e-01 | 6.03e-01 |
| REACTOME NOD1 2 SIGNALING PATHWAY | 33 | 2.55e-01 | 1.14e-01 | 6.03e-01 |
| REACTOME SUMOYLATION OF DNA REPLICATION PROTEINS | 46 | 2.55e-01 | 9.70e-02 | 6.03e-01 |
| REACTOME VLDLR INTERNALISATION AND DEGRADATION | 16 | 2.55e-01 | 1.64e-01 | 6.03e-01 |
| REACTOME ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS | 24 | 2.56e-01 | -1.34e-01 | 6.03e-01 |
| REACTOME NUCLEOTIDE BIOSYNTHESIS | 14 | 2.56e-01 | 1.75e-01 | 6.04e-01 |
| REACTOME INTERLEUKIN 2 FAMILY SIGNALING | 40 | 2.57e-01 | 1.04e-01 | 6.04e-01 |
| REACTOME G PROTEIN MEDIATED EVENTS | 53 | 2.57e-01 | -9.00e-02 | 6.04e-01 |
| REACTOME RESOLUTION OF D LOOP STRUCTURES | 33 | 2.58e-01 | 1.14e-01 | 6.04e-01 |
| REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | 19 | 2.58e-01 | -1.50e-01 | 6.04e-01 |
| REACTOME CHYLOMICRON REMODELING | 10 | 2.58e-01 | -2.06e-01 | 6.04e-01 |
| REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN | 37 | 2.59e-01 | 1.07e-01 | 6.04e-01 |
| REACTOME STIMULI SENSING CHANNELS | 100 | 2.59e-01 | -6.53e-02 | 6.04e-01 |
| REACTOME REGULATION OF NPAS4 MRNA TRANSLATION | 9 | 2.60e-01 | 2.17e-01 | 6.04e-01 |
| REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND | 14 | 2.60e-01 | 1.74e-01 | 6.04e-01 |
| REACTOME SIGNALING BY ERBB2 | 50 | 2.60e-01 | 9.21e-02 | 6.04e-01 |
| REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS | 43 | 2.61e-01 | 9.91e-02 | 6.05e-01 |
| REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | 26 | 2.61e-01 | 1.27e-01 | 6.05e-01 |
| REACTOME REGULATION OF RUNX1 EXPRESSION AND ACTIVITY | 17 | 2.63e-01 | 1.57e-01 | 6.06e-01 |
| REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | 23 | 2.63e-01 | -1.35e-01 | 6.06e-01 |
| REACTOME PI5P REGULATES TP53 ACETYLATION | 9 | 2.63e-01 | 2.16e-01 | 6.06e-01 |
| REACTOME ATORVASTATIN ADME | 9 | 2.64e-01 | -2.15e-01 | 6.06e-01 |
| REACTOME ACYL CHAIN REMODELLING OF PG | 18 | 2.64e-01 | -1.52e-01 | 6.06e-01 |
| REACTOME STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES | 16 | 2.64e-01 | 1.61e-01 | 6.06e-01 |
| REACTOME SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA | 52 | 2.65e-01 | -8.94e-02 | 6.07e-01 |
| REACTOME MRNA EDITING | 10 | 2.67e-01 | 2.03e-01 | 6.12e-01 |
| REACTOME NGF STIMULATED TRANSCRIPTION | 38 | 2.68e-01 | 1.04e-01 | 6.12e-01 |
| REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER | 49 | 2.68e-01 | 9.15e-02 | 6.12e-01 |
| REACTOME GABA RECEPTOR ACTIVATION | 57 | 2.69e-01 | -8.47e-02 | 6.13e-01 |
| REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B | 24 | 2.70e-01 | 1.30e-01 | 6.15e-01 |
| REACTOME SYNTHESIS OF KETONE BODIES | 8 | 2.71e-01 | -2.25e-01 | 6.17e-01 |
| REACTOME MET RECEPTOR ACTIVATION | 6 | 2.72e-01 | -2.59e-01 | 6.17e-01 |
| REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R | 52 | 2.72e-01 | 8.81e-02 | 6.17e-01 |
| REACTOME ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA | 9 | 2.74e-01 | 2.11e-01 | 6.19e-01 |
| REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | 101 | 2.74e-01 | -6.30e-02 | 6.19e-01 |
| REACTOME SIGNALING BY NOTCH2 | 32 | 2.74e-01 | 1.12e-01 | 6.19e-01 |
| REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY | 14 | 2.74e-01 | -1.69e-01 | 6.19e-01 |
| REACTOME SHC1 EVENTS IN EGFR SIGNALING | 14 | 2.75e-01 | 1.68e-01 | 6.19e-01 |
| REACTOME ALK MUTANTS BIND TKIS | 12 | 2.76e-01 | 1.82e-01 | 6.21e-01 |
| REACTOME PHENYLALANINE AND TYROSINE METABOLISM | 11 | 2.78e-01 | 1.89e-01 | 6.25e-01 |
| REACTOME INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL | 14 | 2.82e-01 | 1.66e-01 | 6.31e-01 |
| REACTOME MRNA EDITING C TO U CONVERSION | 8 | 2.82e-01 | 2.20e-01 | 6.31e-01 |
| REACTOME CTLA4 INHIBITORY SIGNALING | 21 | 2.83e-01 | 1.35e-01 | 6.33e-01 |
| REACTOME CREATINE METABOLISM | 9 | 2.83e-01 | 2.06e-01 | 6.33e-01 |
| REACTOME PYRIMIDINE CATABOLISM | 12 | 2.85e-01 | -1.78e-01 | 6.35e-01 |
| REACTOME ECM PROTEOGLYCANS | 73 | 2.88e-01 | -7.20e-02 | 6.41e-01 |
| REACTOME RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES TREGS | 9 | 2.90e-01 | -2.04e-01 | 6.44e-01 |
| REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1 | 16 | 2.90e-01 | 1.53e-01 | 6.44e-01 |
| REACTOME INTERLEUKIN 10 SIGNALING | 43 | 2.90e-01 | 9.33e-02 | 6.44e-01 |
| REACTOME TELOMERE C STRAND LAGGING STRAND SYNTHESIS | 33 | 2.90e-01 | 1.06e-01 | 6.44e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST | 14 | 2.92e-01 | 1.63e-01 | 6.45e-01 |
| REACTOME RUNX3 REGULATES CDKN1A TRANSCRIPTION | 7 | 2.92e-01 | 2.30e-01 | 6.45e-01 |
| REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | 12 | 2.94e-01 | -1.75e-01 | 6.50e-01 |
| REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS | 16 | 2.95e-01 | -1.51e-01 | 6.51e-01 |
| REACTOME SHC RELATED EVENTS TRIGGERED BY IGF1R | 9 | 2.96e-01 | 2.01e-01 | 6.52e-01 |
| REACTOME PI3K EVENTS IN ERBB4 SIGNALING | 10 | 2.97e-01 | 1.91e-01 | 6.52e-01 |
| REACTOME ERK MAPK TARGETS | 20 | 2.98e-01 | 1.35e-01 | 6.53e-01 |
| REACTOME INSULIN RECEPTOR SIGNALLING CASCADE | 53 | 2.98e-01 | 8.27e-02 | 6.53e-01 |
| REACTOME GLYCOLYSIS | 70 | 2.98e-01 | 7.19e-02 | 6.53e-01 |
| REACTOME SIGNALING BY EGFR | 49 | 2.99e-01 | 8.57e-02 | 6.54e-01 |
| REACTOME G2 PHASE | 5 | 2.99e-01 | 2.68e-01 | 6.54e-01 |
| REACTOME PHASE 2 PLATEAU PHASE | 14 | 3.02e-01 | -1.59e-01 | 6.57e-01 |
| REACTOME SIGNALING BY PTK6 | 54 | 3.02e-01 | 8.13e-02 | 6.57e-01 |
| REACTOME FERTILIZATION | 26 | 3.04e-01 | -1.16e-01 | 6.59e-01 |
| REACTOME TRIGLYCERIDE METABOLISM | 35 | 3.04e-01 | 1.00e-01 | 6.59e-01 |
| REACTOME GP1B IX V ACTIVATION SIGNALLING | 11 | 3.04e-01 | 1.79e-01 | 6.59e-01 |
| REACTOME SYNTHESIS OF LIPOXINS LX | 6 | 3.04e-01 | 2.42e-01 | 6.59e-01 |
| REACTOME REGULATED PROTEOLYSIS OF P75NTR | 11 | 3.05e-01 | -1.79e-01 | 6.59e-01 |
| REACTOME RAF INDEPENDENT MAPK1 3 ACTIVATION | 22 | 3.06e-01 | 1.26e-01 | 6.60e-01 |
| REACTOME LTC4 CYSLTR MEDIATED IL4 PRODUCTION | 6 | 3.07e-01 | -2.41e-01 | 6.62e-01 |
| REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS | 46 | 3.08e-01 | 8.69e-02 | 6.63e-01 |
| REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE | 19 | 3.08e-01 | 1.35e-01 | 6.63e-01 |
| REACTOME MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION | 15 | 3.09e-01 | 1.52e-01 | 6.64e-01 |
| REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS | 5 | 3.12e-01 | -2.61e-01 | 6.67e-01 |
| REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1 | 20 | 3.12e-01 | 1.31e-01 | 6.67e-01 |
| REACTOME SIGNALING BY FGFR3 | 39 | 3.12e-01 | 9.35e-02 | 6.67e-01 |
| REACTOME CATION COUPLED CHLORIDE COTRANSPORTERS | 7 | 3.13e-01 | 2.20e-01 | 6.67e-01 |
| REACTOME RA BIOSYNTHESIS PATHWAY | 22 | 3.13e-01 | 1.24e-01 | 6.67e-01 |
| REACTOME RNA POLYMERASE II TRANSCRIBES SNRNA GENES | 77 | 3.13e-01 | 6.65e-02 | 6.67e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION BY RUNX2 | 117 | 3.14e-01 | 5.39e-02 | 6.68e-01 |
| REACTOME PLATELET SENSITIZATION BY LDL | 17 | 3.15e-01 | 1.41e-01 | 6.69e-01 |
| REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES | 27 | 3.15e-01 | 1.12e-01 | 6.69e-01 |
| REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY | 25 | 3.16e-01 | 1.16e-01 | 6.69e-01 |
| REACTOME MTORC1 MEDIATED SIGNALLING | 23 | 3.18e-01 | 1.20e-01 | 6.74e-01 |
| REACTOME MEIOTIC SYNAPSIS | 73 | 3.19e-01 | 6.75e-02 | 6.75e-01 |
| REACTOME PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1 | 9 | 3.20e-01 | 1.91e-01 | 6.77e-01 |
| REACTOME POLB DEPENDENT LONG PATCH BASE EXCISION REPAIR | 8 | 3.21e-01 | 2.03e-01 | 6.77e-01 |
| REACTOME GAP JUNCTION DEGRADATION | 12 | 3.21e-01 | 1.65e-01 | 6.77e-01 |
| REACTOME CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY | 25 | 3.22e-01 | 1.14e-01 | 6.77e-01 |
| REACTOME SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER | 15 | 3.22e-01 | 1.48e-01 | 6.77e-01 |
| REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | 29 | 3.22e-01 | 1.06e-01 | 6.77e-01 |
| REACTOME ERKS ARE INACTIVATED | 13 | 3.25e-01 | 1.58e-01 | 6.80e-01 |
| REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION | 31 | 3.25e-01 | 1.02e-01 | 6.80e-01 |
| REACTOME EGFR DOWNREGULATION | 30 | 3.25e-01 | 1.04e-01 | 6.80e-01 |
| REACTOME CROSSLINKING OF COLLAGEN FIBRILS | 16 | 3.26e-01 | -1.42e-01 | 6.80e-01 |
| REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH | 62 | 3.26e-01 | -7.22e-02 | 6.80e-01 |
| REACTOME PRE NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM | 6 | 3.26e-01 | -2.31e-01 | 6.80e-01 |
| REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | 19 | 3.29e-01 | 1.29e-01 | 6.85e-01 |
| REACTOME SYNTHESIS OF PI | 5 | 3.29e-01 | -2.52e-01 | 6.85e-01 |
| REACTOME HDL ASSEMBLY | 8 | 3.31e-01 | 1.99e-01 | 6.86e-01 |
| REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE | 69 | 3.31e-01 | -6.77e-02 | 6.86e-01 |
| REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | 21 | 3.33e-01 | 1.22e-01 | 6.89e-01 |
| REACTOME RUNX3 REGULATES YAP1 MEDIATED TRANSCRIPTION | 8 | 3.33e-01 | -1.98e-01 | 6.89e-01 |
| REACTOME PHOSPHORYLATION OF EMI1 | 6 | 3.36e-01 | 2.27e-01 | 6.93e-01 |
| REACTOME AMINO ACID CONJUGATION | 9 | 3.36e-01 | -1.85e-01 | 6.93e-01 |
| REACTOME P38MAPK EVENTS | 13 | 3.38e-01 | 1.53e-01 | 6.93e-01 |
| REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING | 32 | 3.38e-01 | 9.78e-02 | 6.93e-01 |
| REACTOME SYNTHESIS OF 5 EICOSATETRAENOIC ACIDS | 9 | 3.39e-01 | 1.84e-01 | 6.93e-01 |
| REACTOME RUNX3 REGULATES P14 ARF | 10 | 3.39e-01 | 1.75e-01 | 6.93e-01 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS | 7 | 3.39e-01 | -2.09e-01 | 6.93e-01 |
| REACTOME GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | 34 | 3.39e-01 | 9.47e-02 | 6.93e-01 |
| REACTOME G BETA GAMMA SIGNALLING THROUGH CDC42 | 19 | 3.39e-01 | 1.27e-01 | 6.93e-01 |
| REACTOME TLR3 MEDIATED TICAM1 DEPENDENT PROGRAMMED CELL DEATH | 6 | 3.40e-01 | 2.25e-01 | 6.93e-01 |
| REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | 183 | 3.40e-01 | 4.09e-02 | 6.93e-01 |
| REACTOME ENDOSOMAL VACUOLAR PATHWAY | 11 | 3.42e-01 | -1.65e-01 | 6.95e-01 |
| REACTOME SMALL INTERFERING RNA SIRNA BIOGENESIS | 9 | 3.42e-01 | 1.83e-01 | 6.95e-01 |
| REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | 11 | 3.43e-01 | 1.65e-01 | 6.95e-01 |
| REACTOME SIGNALING BY HIPPO | 19 | 3.43e-01 | -1.26e-01 | 6.95e-01 |
| REACTOME ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM | 12 | 3.44e-01 | 1.58e-01 | 6.96e-01 |
| REACTOME DEFENSINS | 33 | 3.44e-01 | -9.52e-02 | 6.96e-01 |
| REACTOME RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES | 16 | 3.44e-01 | -1.37e-01 | 6.96e-01 |
| REACTOME SIGNALING BY TGFB FAMILY MEMBERS | 119 | 3.45e-01 | 5.01e-02 | 6.96e-01 |
| REACTOME REGULATION OF BETA CELL DEVELOPMENT | 41 | 3.45e-01 | 8.52e-02 | 6.96e-01 |
| REACTOME STAT3 NUCLEAR EVENTS DOWNSTREAM OF ALK SIGNALING | 9 | 3.47e-01 | 1.81e-01 | 6.97e-01 |
| REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS | 81 | 3.47e-01 | 6.04e-02 | 6.97e-01 |
| REACTOME REGULATION OF TP53 EXPRESSION AND DEGRADATION | 37 | 3.48e-01 | 8.92e-02 | 6.97e-01 |
| REACTOME NUCLEAR IMPORT OF REV PROTEIN | 34 | 3.48e-01 | 9.30e-02 | 6.97e-01 |
| REACTOME MITOCHONDRIAL CALCIUM ION TRANSPORT | 23 | 3.48e-01 | -1.13e-01 | 6.97e-01 |
| REACTOME DSCAM INTERACTIONS | 11 | 3.49e-01 | -1.63e-01 | 6.97e-01 |
| REACTOME ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN | 13 | 3.49e-01 | -1.50e-01 | 6.97e-01 |
| REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS | 34 | 3.49e-01 | -9.28e-02 | 6.97e-01 |
| REACTOME BILE ACID AND BILE SALT METABOLISM | 45 | 3.50e-01 | -8.05e-02 | 6.98e-01 |
| REACTOME SIGNALING BY LRP5 MUTANTS | 6 | 3.50e-01 | 2.20e-01 | 6.98e-01 |
| REACTOME ACTIVATION OF SMO | 18 | 3.51e-01 | -1.27e-01 | 6.98e-01 |
| REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING | 28 | 3.51e-01 | 1.02e-01 | 6.98e-01 |
| REACTOME NEUREXINS AND NEUROLIGINS | 51 | 3.52e-01 | -7.53e-02 | 6.99e-01 |
| REACTOME UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN | 6 | 3.53e-01 | 2.19e-01 | 7.01e-01 |
| REACTOME IRS MEDIATED SIGNALLING | 47 | 3.54e-01 | 7.81e-02 | 7.01e-01 |
| REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | 9 | 3.54e-01 | 1.78e-01 | 7.01e-01 |
| REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | 14 | 3.55e-01 | 1.43e-01 | 7.01e-01 |
| REACTOME REGULATION OF PTEN LOCALIZATION | 8 | 3.55e-01 | 1.89e-01 | 7.01e-01 |
| REACTOME ION CHANNEL TRANSPORT | 172 | 3.56e-01 | -4.08e-02 | 7.03e-01 |
| REACTOME SIGNALING BY MAPK MUTANTS | 6 | 3.57e-01 | 2.17e-01 | 7.03e-01 |
| REACTOME INTERFERON ALPHA BETA SIGNALING | 70 | 3.59e-01 | 6.34e-02 | 7.06e-01 |
| REACTOME PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR | 21 | 3.61e-01 | 1.15e-01 | 7.06e-01 |
| REACTOME CHOLESTEROL BIOSYNTHESIS | 25 | 3.61e-01 | 1.06e-01 | 7.06e-01 |
| REACTOME FCGR ACTIVATION | 11 | 3.61e-01 | 1.59e-01 | 7.06e-01 |
| REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS | 53 | 3.61e-01 | 7.25e-02 | 7.06e-01 |
| REACTOME SIGNALING BY FGFR1 | 49 | 3.62e-01 | 7.53e-02 | 7.06e-01 |
| REACTOME DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS | 19 | 3.62e-01 | 1.21e-01 | 7.06e-01 |
| REACTOME EICOSANOIDS | 12 | 3.62e-01 | 1.52e-01 | 7.06e-01 |
| REACTOME RHOB GTPASE CYCLE | 67 | 3.62e-01 | -6.43e-02 | 7.06e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION BY VENTX | 41 | 3.63e-01 | 8.21e-02 | 7.06e-01 |
| REACTOME DOWNREGULATION OF ERBB4 SIGNALING | 9 | 3.64e-01 | 1.75e-01 | 7.06e-01 |
| REACTOME DEFECTIVE CHSY1 CAUSES TPBS | 7 | 3.64e-01 | 1.98e-01 | 7.06e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS | 29 | 3.64e-01 | 9.74e-02 | 7.06e-01 |
| REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX | 36 | 3.65e-01 | 8.72e-02 | 7.06e-01 |
| REACTOME SUMOYLATION OF IMMUNE RESPONSE PROTEINS | 10 | 3.66e-01 | 1.65e-01 | 7.06e-01 |
| REACTOME BIOSYNTHESIS OF MARESINS | 8 | 3.66e-01 | -1.85e-01 | 7.06e-01 |
| REACTOME ACTIVATION OF NIMA KINASES NEK9 NEK6 NEK7 | 7 | 3.66e-01 | 1.97e-01 | 7.06e-01 |
| REACTOME TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX | 14 | 3.67e-01 | 1.39e-01 | 7.07e-01 |
| REACTOME RAC1 GTPASE CYCLE | 172 | 3.67e-01 | -3.99e-02 | 7.07e-01 |
| REACTOME REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS | 15 | 3.68e-01 | 1.34e-01 | 7.07e-01 |
| REACTOME RAC3 GTPASE CYCLE | 85 | 3.69e-01 | 5.64e-02 | 7.07e-01 |
| REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX IN CANCER | 8 | 3.69e-01 | 1.84e-01 | 7.07e-01 |
| REACTOME CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS | 19 | 3.69e-01 | 1.19e-01 | 7.07e-01 |
| REACTOME TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT | 18 | 3.70e-01 | 1.22e-01 | 7.08e-01 |
| REACTOME MITOCHONDRIAL UNCOUPLING | 5 | 3.71e-01 | -2.31e-01 | 7.08e-01 |
| REACTOME RIBAVIRIN ADME | 11 | 3.71e-01 | -1.56e-01 | 7.08e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS | 12 | 3.72e-01 | -1.49e-01 | 7.08e-01 |
| REACTOME EXTRA NUCLEAR ESTROGEN SIGNALING | 74 | 3.72e-01 | 6.01e-02 | 7.08e-01 |
| REACTOME CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS | 100 | 3.74e-01 | 5.15e-02 | 7.09e-01 |
| REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION | 26 | 3.74e-01 | 1.01e-01 | 7.09e-01 |
| REACTOME SIGNALING BY ERBB2 IN CANCER | 26 | 3.74e-01 | 1.01e-01 | 7.09e-01 |
| REACTOME RHO GTPASES ACTIVATE NADPH OXIDASES | 21 | 3.76e-01 | 1.12e-01 | 7.09e-01 |
| REACTOME INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING | 103 | 3.78e-01 | 5.03e-02 | 7.09e-01 |
| REACTOME 2 LTR CIRCLE FORMATION | 7 | 3.78e-01 | 1.92e-01 | 7.09e-01 |
| REACTOME REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE | 81 | 3.78e-01 | 5.67e-02 | 7.09e-01 |
| REACTOME TRANSPORT OF FATTY ACIDS | 8 | 3.78e-01 | -1.80e-01 | 7.09e-01 |
| REACTOME ANCHORING FIBRIL FORMATION | 13 | 3.78e-01 | -1.41e-01 | 7.09e-01 |
| REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES | 14 | 3.79e-01 | -1.36e-01 | 7.09e-01 |
| REACTOME RECEPTOR MEDIATED MITOPHAGY | 10 | 3.79e-01 | 1.61e-01 | 7.09e-01 |
| REACTOME NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 22 | 3.79e-01 | 1.08e-01 | 7.09e-01 |
| REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES | 7 | 3.79e-01 | -1.92e-01 | 7.09e-01 |
| REACTOME NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10 | 12 | 3.80e-01 | 1.47e-01 | 7.09e-01 |
| REACTOME SYNTHESIS OF DOLICHYL PHOSPHATE | 6 | 3.80e-01 | 2.07e-01 | 7.09e-01 |
| REACTOME SULFIDE OXIDATION TO SULFATE | 6 | 3.80e-01 | 2.07e-01 | 7.09e-01 |
| REACTOME SENSORY PROCESSING OF SOUND | 72 | 3.80e-01 | -5.99e-02 | 7.09e-01 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS | 9 | 3.80e-01 | -1.69e-01 | 7.09e-01 |
| REACTOME SIGNALING BY FGFR | 85 | 3.82e-01 | 5.49e-02 | 7.09e-01 |
| REACTOME SIGNALING BY ALK | 26 | 3.82e-01 | 9.91e-02 | 7.09e-01 |
| REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION | 23 | 3.82e-01 | -1.05e-01 | 7.09e-01 |
| REACTOME PARASITE INFECTION | 57 | 3.82e-01 | 6.69e-02 | 7.09e-01 |
| REACTOME INTEGRATION OF PROVIRUS | 9 | 3.83e-01 | 1.68e-01 | 7.09e-01 |
| REACTOME NS1 MEDIATED EFFECTS ON HOST PATHWAYS | 41 | 3.83e-01 | 7.88e-02 | 7.09e-01 |
| REACTOME GABA B RECEPTOR ACTIVATION | 43 | 3.86e-01 | -7.64e-02 | 7.14e-01 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS | 9 | 3.87e-01 | -1.67e-01 | 7.14e-01 |
| REACTOME GLYCOGEN STORAGE DISEASES | 15 | 3.87e-01 | 1.29e-01 | 7.14e-01 |
| REACTOME INTERLEUKIN 6 SIGNALING | 11 | 3.87e-01 | 1.51e-01 | 7.14e-01 |
| REACTOME FANCONI ANEMIA PATHWAY | 35 | 3.89e-01 | 8.42e-02 | 7.16e-01 |
| REACTOME ACTIVATED NTRK3 SIGNALS THROUGH RAS | 8 | 3.89e-01 | 1.76e-01 | 7.16e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS | 36 | 3.90e-01 | 8.28e-02 | 7.16e-01 |
| REACTOME ASPARTATE AND ASPARAGINE METABOLISM | 11 | 3.90e-01 | 1.50e-01 | 7.16e-01 |
| REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS | 6 | 3.91e-01 | -2.02e-01 | 7.16e-01 |
| REACTOME HIV TRANSCRIPTION ELONGATION | 42 | 3.91e-01 | 7.65e-02 | 7.17e-01 |
| REACTOME MOLYBDENUM COFACTOR BIOSYNTHESIS | 6 | 3.92e-01 | 2.02e-01 | 7.17e-01 |
| REACTOME COPI MEDIATED ANTEROGRADE TRANSPORT | 101 | 3.92e-01 | 4.93e-02 | 7.17e-01 |
| REACTOME SIGNALING BY FGFR1 IN DISEASE | 38 | 3.95e-01 | 7.97e-02 | 7.20e-01 |
| REACTOME PECAM1 INTERACTIONS | 12 | 3.95e-01 | 1.42e-01 | 7.20e-01 |
| REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS | 18 | 3.96e-01 | 1.16e-01 | 7.20e-01 |
| REACTOME DEFECTIVE F9 ACTIVATION | 5 | 3.96e-01 | 2.19e-01 | 7.20e-01 |
| REACTOME PROTEIN REPAIR | 6 | 3.97e-01 | -2.00e-01 | 7.20e-01 |
| REACTOME HEDGEHOG OFF STATE | 111 | 3.97e-01 | 4.66e-02 | 7.20e-01 |
| REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | 23 | 3.97e-01 | -1.02e-01 | 7.20e-01 |
| REACTOME FGFR3 LIGAND BINDING AND ACTIVATION | 12 | 3.98e-01 | 1.41e-01 | 7.20e-01 |
| REACTOME GLUCOSE METABOLISM | 90 | 3.98e-01 | 5.15e-02 | 7.20e-01 |
| REACTOME MATURATION OF SARS COV 2 NUCLEOPROTEIN | 15 | 3.98e-01 | -1.26e-01 | 7.20e-01 |
| REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | 15 | 3.98e-01 | -1.26e-01 | 7.20e-01 |
| REACTOME SUMOYLATION OF SUMOYLATION PROTEINS | 35 | 4.00e-01 | 8.22e-02 | 7.21e-01 |
| REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI | 26 | 4.00e-01 | -9.53e-02 | 7.21e-01 |
| REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL | 41 | 4.01e-01 | 7.58e-02 | 7.21e-01 |
| REACTOME ACTIVATION OF TRKA RECEPTORS | 6 | 4.01e-01 | 1.98e-01 | 7.21e-01 |
| REACTOME AMINE LIGAND BINDING RECEPTORS | 40 | 4.03e-01 | 7.65e-02 | 7.21e-01 |
| REACTOME DISEASES OF CARBOHYDRATE METABOLISM | 31 | 4.03e-01 | 8.68e-02 | 7.21e-01 |
| REACTOME CYP2E1 REACTIONS | 10 | 4.03e-01 | -1.53e-01 | 7.21e-01 |
| REACTOME MASTL FACILITATES MITOTIC PROGRESSION | 10 | 4.04e-01 | -1.53e-01 | 7.21e-01 |
| REACTOME FCGR3A MEDIATED IL10 SYNTHESIS | 36 | 4.04e-01 | -8.04e-02 | 7.21e-01 |
| REACTOME EFFECTS OF PIP2 HYDROLYSIS | 26 | 4.04e-01 | -9.45e-02 | 7.21e-01 |
| REACTOME G1 S SPECIFIC TRANSCRIPTION | 28 | 4.04e-01 | 9.10e-02 | 7.21e-01 |
| REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS | 42 | 4.05e-01 | 7.43e-02 | 7.21e-01 |
| REACTOME INWARDLY RECTIFYING K CHANNELS | 35 | 4.05e-01 | -8.14e-02 | 7.21e-01 |
| REACTOME SUMOYLATION OF RNA BINDING PROTEINS | 47 | 4.06e-01 | 7.00e-02 | 7.22e-01 |
| REACTOME RHOV GTPASE CYCLE | 36 | 4.06e-01 | -8.00e-02 | 7.22e-01 |
| REACTOME CROSS PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS PHAGOSOMES | 6 | 4.07e-01 | 1.95e-01 | 7.23e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE | 20 | 4.09e-01 | 1.07e-01 | 7.25e-01 |
| REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION | 29 | 4.10e-01 | 8.83e-02 | 7.27e-01 |
| REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | 89 | 4.12e-01 | -5.03e-02 | 7.29e-01 |
| REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS | 17 | 4.14e-01 | -1.14e-01 | 7.31e-01 |
| REACTOME CD163 MEDIATING AN ANTI INFLAMMATORY RESPONSE | 9 | 4.15e-01 | 1.57e-01 | 7.31e-01 |
| REACTOME CHREBP ACTIVATES METABOLIC GENE EXPRESSION | 8 | 4.16e-01 | -1.66e-01 | 7.31e-01 |
| REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS | 14 | 4.16e-01 | 1.26e-01 | 7.31e-01 |
| REACTOME FGFR1B LIGAND BINDING AND ACTIVATION | 6 | 4.16e-01 | 1.92e-01 | 7.31e-01 |
| REACTOME ACTIVATION OF CASPASES THROUGH APOPTOSOME MEDIATED CLEAVAGE | 5 | 4.16e-01 | 2.10e-01 | 7.31e-01 |
| REACTOME PIWI INTERACTING RNA PIRNA BIOGENESIS | 29 | 4.17e-01 | -8.71e-02 | 7.31e-01 |
| REACTOME INITIAL TRIGGERING OF COMPLEMENT | 21 | 4.17e-01 | -1.02e-01 | 7.31e-01 |
| REACTOME RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS | 5 | 4.17e-01 | -2.10e-01 | 7.31e-01 |
| REACTOME RECYCLING OF BILE ACIDS AND SALTS | 18 | 4.18e-01 | -1.10e-01 | 7.31e-01 |
| REACTOME SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS | 14 | 4.18e-01 | -1.25e-01 | 7.31e-01 |
| REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS | 11 | 4.19e-01 | 1.41e-01 | 7.31e-01 |
| REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES | 21 | 4.20e-01 | -1.02e-01 | 7.31e-01 |
| REACTOME ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY | 10 | 4.21e-01 | 1.47e-01 | 7.31e-01 |
| REACTOME TAK1 DEPENDENT IKK AND NF KAPPA B ACTIVATION | 41 | 4.21e-01 | 7.26e-02 | 7.31e-01 |
| REACTOME P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1 | 6 | 4.22e-01 | 1.89e-01 | 7.31e-01 |
| REACTOME CD28 DEPENDENT PI3K AKT SIGNALING | 22 | 4.22e-01 | 9.88e-02 | 7.31e-01 |
| REACTOME GRB2 EVENTS IN ERBB2 SIGNALING | 16 | 4.23e-01 | 1.16e-01 | 7.31e-01 |
| REACTOME DEFECTS IN BIOTIN BTN METABOLISM | 8 | 4.23e-01 | -1.64e-01 | 7.31e-01 |
| REACTOME SYNTHESIS OF DIPHTHAMIDE EEF2 | 8 | 4.23e-01 | 1.64e-01 | 7.31e-01 |
| REACTOME BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA | 5 | 4.23e-01 | 2.07e-01 | 7.31e-01 |
| REACTOME EPHA MEDIATED GROWTH CONE COLLAPSE | 29 | 4.24e-01 | -8.58e-02 | 7.31e-01 |
| REACTOME SIGNALING BY BMP | 27 | 4.25e-01 | -8.88e-02 | 7.31e-01 |
| REACTOME SIGNALING BY NTRK2 TRKB | 25 | 4.25e-01 | 9.22e-02 | 7.31e-01 |
| REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | 122 | 4.25e-01 | -4.18e-02 | 7.31e-01 |
| REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | 23 | 4.25e-01 | -9.60e-02 | 7.31e-01 |
| REACTOME RND1 GTPASE CYCLE | 41 | 4.25e-01 | -7.19e-02 | 7.31e-01 |
| REACTOME LDL REMODELING | 6 | 4.26e-01 | 1.88e-01 | 7.32e-01 |
| REACTOME HDR THROUGH SINGLE STRAND ANNEALING SSA | 37 | 4.27e-01 | 7.55e-02 | 7.33e-01 |
| REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA | 25 | 4.28e-01 | 9.15e-02 | 7.34e-01 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH CDK5 | 6 | 4.28e-01 | -1.87e-01 | 7.34e-01 |
| REACTOME COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC | 52 | 4.32e-01 | 6.30e-02 | 7.39e-01 |
| REACTOME SCAVENGING BY CLASS F RECEPTORS | 6 | 4.35e-01 | 1.84e-01 | 7.43e-01 |
| REACTOME RUNX2 REGULATES CHONDROCYTE MATURATION | 5 | 4.36e-01 | -2.01e-01 | 7.44e-01 |
| REACTOME HEME DEGRADATION | 15 | 4.37e-01 | -1.16e-01 | 7.44e-01 |
| REACTOME TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE | 10 | 4.37e-01 | -1.42e-01 | 7.45e-01 |
| REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS | 12 | 4.40e-01 | -1.29e-01 | 7.48e-01 |
| REACTOME CGMP EFFECTS | 16 | 4.41e-01 | -1.11e-01 | 7.48e-01 |
| REACTOME CILIUM ASSEMBLY | 190 | 4.41e-01 | -3.24e-02 | 7.48e-01 |
| REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE | 277 | 4.42e-01 | 2.68e-02 | 7.48e-01 |
| REACTOME BETA OXIDATION OF BUTANOYL COA TO ACETYL COA | 5 | 4.43e-01 | 1.98e-01 | 7.48e-01 |
| REACTOME SENSING OF DNA DOUBLE STRAND BREAKS | 6 | 4.43e-01 | 1.81e-01 | 7.48e-01 |
| REACTOME REGULATION OF NPAS4 GENE EXPRESSION | 13 | 4.44e-01 | 1.23e-01 | 7.48e-01 |
| REACTOME UPTAKE AND FUNCTION OF ANTHRAX TOXINS | 11 | 4.45e-01 | -1.33e-01 | 7.48e-01 |
| REACTOME RHO GTPASES ACTIVATE IQGAPS | 31 | 4.45e-01 | 7.93e-02 | 7.48e-01 |
| REACTOME ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA | 15 | 4.45e-01 | 1.14e-01 | 7.48e-01 |
| REACTOME AURKA ACTIVATION BY TPX2 | 69 | 4.45e-01 | -5.32e-02 | 7.48e-01 |
| REACTOME HYALURONAN BIOSYNTHESIS AND EXPORT | 5 | 4.46e-01 | 1.97e-01 | 7.48e-01 |
| REACTOME ENDOGENOUS STEROLS | 26 | 4.46e-01 | -8.63e-02 | 7.48e-01 |
| REACTOME FRS MEDIATED FGFR4 SIGNALING | 21 | 4.46e-01 | 9.60e-02 | 7.48e-01 |
| REACTOME REDUCTION OF CYTOSOLIC CA LEVELS | 11 | 4.46e-01 | -1.33e-01 | 7.48e-01 |
| REACTOME DEFECTIVE CHST3 CAUSES SEDCJD | 7 | 4.46e-01 | 1.66e-01 | 7.48e-01 |
| REACTOME LYSOSOME VESICLE BIOGENESIS | 33 | 4.47e-01 | 7.65e-02 | 7.48e-01 |
| REACTOME WNT MEDIATED ACTIVATION OF DVL | 8 | 4.47e-01 | 1.55e-01 | 7.48e-01 |
| REACTOME HDL REMODELING | 10 | 4.48e-01 | 1.39e-01 | 7.48e-01 |
| REACTOME LAGGING STRAND SYNTHESIS | 19 | 4.48e-01 | 1.00e-01 | 7.48e-01 |
| REACTOME POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE | 25 | 4.52e-01 | 8.69e-02 | 7.53e-01 |
| REACTOME ACTIVATION OF PPARGC1A PGC 1ALPHA BY PHOSPHORYLATION | 10 | 4.52e-01 | 1.37e-01 | 7.53e-01 |
| REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | 9 | 4.52e-01 | 1.45e-01 | 7.53e-01 |
| REACTOME PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING | 5 | 4.54e-01 | 1.93e-01 | 7.55e-01 |
| REACTOME NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 19 | 4.55e-01 | -9.90e-02 | 7.55e-01 |
| REACTOME SEMAPHORIN INTERACTIONS | 61 | 4.55e-01 | -5.53e-02 | 7.55e-01 |
| REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM | 45 | 4.56e-01 | -6.43e-02 | 7.55e-01 |
| REACTOME METAL ION SLC TRANSPORTERS | 23 | 4.56e-01 | -8.98e-02 | 7.55e-01 |
| REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB | 5 | 4.58e-01 | 1.92e-01 | 7.57e-01 |
| REACTOME VEGFR2 MEDIATED CELL PROLIFERATION | 19 | 4.60e-01 | -9.78e-02 | 7.60e-01 |
| REACTOME NRCAM INTERACTIONS | 6 | 4.61e-01 | -1.74e-01 | 7.60e-01 |
| REACTOME NEF AND SIGNAL TRANSDUCTION | 8 | 4.62e-01 | 1.50e-01 | 7.61e-01 |
| REACTOME SYNAPTIC ADHESION LIKE MOLECULES | 19 | 4.62e-01 | 9.74e-02 | 7.61e-01 |
| REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS | 35 | 4.63e-01 | 7.16e-02 | 7.62e-01 |
| REACTOME PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE | 74 | 4.64e-01 | 4.92e-02 | 7.63e-01 |
| REACTOME ESTABLISHMENT OF SISTER CHROMATID COHESION | 9 | 4.66e-01 | 1.40e-01 | 7.64e-01 |
| REACTOME RHOJ GTPASE CYCLE | 51 | 4.69e-01 | -5.87e-02 | 7.68e-01 |
| REACTOME COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC | 98 | 4.69e-01 | 4.23e-02 | 7.68e-01 |
| REACTOME ASSEMBLY OF THE HIV VIRION | 16 | 4.69e-01 | 1.04e-01 | 7.68e-01 |
| REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX | 9 | 4.71e-01 | 1.39e-01 | 7.70e-01 |
| REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES | 16 | 4.72e-01 | 1.04e-01 | 7.70e-01 |
| REACTOME GAP JUNCTION TRAFFICKING AND REGULATION | 49 | 4.72e-01 | -5.94e-02 | 7.70e-01 |
| REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE | 22 | 4.72e-01 | -8.85e-02 | 7.70e-01 |
| REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX | 13 | 4.75e-01 | 1.14e-01 | 7.74e-01 |
| REACTOME METABOLISM OF NUCLEOTIDES | 94 | 4.78e-01 | 4.23e-02 | 7.77e-01 |
| REACTOME PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS | 7 | 4.78e-01 | 1.55e-01 | 7.77e-01 |
| REACTOME MITOTIC TELOPHASE CYTOKINESIS | 11 | 4.78e-01 | 1.23e-01 | 7.77e-01 |
| REACTOME CHL1 INTERACTIONS | 9 | 4.82e-01 | -1.35e-01 | 7.82e-01 |
| REACTOME UREA CYCLE | 9 | 4.83e-01 | -1.35e-01 | 7.82e-01 |
| REACTOME VOLTAGE GATED POTASSIUM CHANNELS | 42 | 4.83e-01 | -6.25e-02 | 7.82e-01 |
| REACTOME FCERI MEDIATED CA 2 MOBILIZATION | 30 | 4.83e-01 | 7.40e-02 | 7.82e-01 |
| REACTOME LIGAND RECEPTOR INTERACTIONS | 8 | 4.84e-01 | -1.43e-01 | 7.82e-01 |
| REACTOME VLDL CLEARANCE | 6 | 4.86e-01 | 1.64e-01 | 7.84e-01 |
| REACTOME G ALPHA I SIGNALLING EVENTS | 304 | 4.89e-01 | 2.31e-02 | 7.88e-01 |
| REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | 51 | 4.89e-01 | 5.60e-02 | 7.88e-01 |
| REACTOME SIGNALING BY FGFR IN DISEASE | 62 | 4.91e-01 | 5.06e-02 | 7.88e-01 |
| REACTOME EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION | 27 | 4.91e-01 | -7.65e-02 | 7.88e-01 |
| REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION | 23 | 4.91e-01 | 8.29e-02 | 7.88e-01 |
| REACTOME SHC1 EVENTS IN ERBB2 SIGNALING | 22 | 4.92e-01 | 8.46e-02 | 7.88e-01 |
| REACTOME PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS | 21 | 4.92e-01 | 8.66e-02 | 7.88e-01 |
| REACTOME SEMA4D IN SEMAPHORIN SIGNALING | 24 | 4.92e-01 | -8.10e-02 | 7.88e-01 |
| REACTOME ANTIMICROBIAL PEPTIDES | 76 | 4.93e-01 | -4.55e-02 | 7.88e-01 |
| REACTOME SCAVENGING BY CLASS A RECEPTORS | 19 | 4.93e-01 | 9.08e-02 | 7.88e-01 |
| REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | 12 | 4.93e-01 | 1.14e-01 | 7.88e-01 |
| REACTOME G ALPHA Q SIGNALLING EVENTS | 206 | 4.96e-01 | 2.75e-02 | 7.91e-01 |
| REACTOME TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA | 36 | 4.96e-01 | 6.55e-02 | 7.91e-01 |
| REACTOME PURINE SALVAGE | 12 | 4.98e-01 | 1.13e-01 | 7.93e-01 |
| REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE | 93 | 4.99e-01 | -4.06e-02 | 7.94e-01 |
| REACTOME RSK ACTIVATION | 5 | 5.00e-01 | -1.74e-01 | 7.94e-01 |
| REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | 20 | 5.02e-01 | -8.68e-02 | 7.96e-01 |
| REACTOME METABOLISM OF LIPIDS | 709 | 5.05e-01 | 1.47e-02 | 7.98e-01 |
| REACTOME CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY | 12 | 5.05e-01 | 1.11e-01 | 7.98e-01 |
| REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | 21 | 5.05e-01 | 8.39e-02 | 7.98e-01 |
| REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | 15 | 5.05e-01 | 9.93e-02 | 7.98e-01 |
| REACTOME RESPONSE TO METAL IONS | 14 | 5.06e-01 | 1.03e-01 | 7.98e-01 |
| REACTOME ROLE OF ABL IN ROBO SLIT SIGNALING | 8 | 5.07e-01 | -1.35e-01 | 7.98e-01 |
| REACTOME OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS | 8 | 5.07e-01 | 1.35e-01 | 7.98e-01 |
| REACTOME METABOLISM OF AMINE DERIVED HORMONES | 17 | 5.08e-01 | -9.28e-02 | 7.98e-01 |
| REACTOME INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS | 37 | 5.08e-01 | 6.29e-02 | 7.98e-01 |
| REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS | 27 | 5.08e-01 | 7.36e-02 | 7.98e-01 |
| REACTOME SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION | 8 | 5.08e-01 | -1.35e-01 | 7.98e-01 |
| REACTOME CELL CELL COMMUNICATION | 126 | 5.09e-01 | -3.41e-02 | 7.98e-01 |
| REACTOME CIPROFLOXACIN ADME | 5 | 5.09e-01 | 1.71e-01 | 7.98e-01 |
| REACTOME METABOLISM OF STEROID HORMONES | 35 | 5.10e-01 | -6.44e-02 | 7.99e-01 |
| REACTOME NUCLEAR PORE COMPLEX NPC DISASSEMBLY | 36 | 5.12e-01 | 6.31e-02 | 8.02e-01 |
| REACTOME FATTY ACYL COA BIOSYNTHESIS | 36 | 5.14e-01 | -6.29e-02 | 8.03e-01 |
| REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | 45 | 5.16e-01 | 5.60e-02 | 8.06e-01 |
| REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE | 37 | 5.17e-01 | 6.16e-02 | 8.06e-01 |
| REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | 20 | 5.18e-01 | 8.36e-02 | 8.07e-01 |
| REACTOME LEISHMANIA INFECTION | 156 | 5.19e-01 | 2.99e-02 | 8.08e-01 |
| REACTOME HSF1 DEPENDENT TRANSACTIVATION | 37 | 5.20e-01 | -6.12e-02 | 8.08e-01 |
| REACTOME BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA | 5 | 5.20e-01 | 1.66e-01 | 8.08e-01 |
| REACTOME MULTIFUNCTIONAL ANION EXCHANGERS | 9 | 5.20e-01 | -1.24e-01 | 8.08e-01 |
| REACTOME NOSTRIN MEDIATED ENOS TRAFFICKING | 5 | 5.21e-01 | -1.66e-01 | 8.08e-01 |
| REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2 | 17 | 5.23e-01 | 8.95e-02 | 8.10e-01 |
| REACTOME SUMOYLATION OF DNA METHYLATION PROTEINS | 16 | 5.23e-01 | -9.22e-02 | 8.10e-01 |
| REACTOME VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS | 42 | 5.24e-01 | -5.69e-02 | 8.10e-01 |
| REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX | 21 | 5.25e-01 | 8.01e-02 | 8.12e-01 |
| REACTOME LOSS OF FUNCTION OF SMAD2 3 IN CANCER | 7 | 5.28e-01 | 1.38e-01 | 8.15e-01 |
| REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | 28 | 5.28e-01 | -6.88e-02 | 8.15e-01 |
| REACTOME INTERLEUKIN RECEPTOR SHC SIGNALING | 24 | 5.28e-01 | 7.44e-02 | 8.15e-01 |
| REACTOME SIGNAL ATTENUATION | 10 | 5.29e-01 | 1.15e-01 | 8.15e-01 |
| REACTOME TRANSPORT OF RCBL WITHIN THE BODY | 8 | 5.32e-01 | 1.28e-01 | 8.19e-01 |
| REACTOME MET RECEPTOR RECYCLING | 10 | 5.33e-01 | -1.14e-01 | 8.19e-01 |
| REACTOME DEFECTIVE CSF2RB CAUSES SMDP5 | 7 | 5.34e-01 | 1.36e-01 | 8.20e-01 |
| REACTOME RHOA GTPASE CYCLE | 142 | 5.34e-01 | -3.02e-02 | 8.20e-01 |
| REACTOME VLDL ASSEMBLY | 5 | 5.36e-01 | 1.60e-01 | 8.22e-01 |
| REACTOME O LINKED GLYCOSYLATION OF MUCINS | 61 | 5.37e-01 | -4.57e-02 | 8.22e-01 |
| REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS | 20 | 5.37e-01 | 7.97e-02 | 8.22e-01 |
| REACTOME REGULATION OF MECP2 EXPRESSION AND ACTIVITY | 30 | 5.41e-01 | 6.45e-02 | 8.24e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES | 12 | 5.41e-01 | -1.02e-01 | 8.24e-01 |
| REACTOME CLEC7A INFLAMMASOME PATHWAY | 6 | 5.42e-01 | -1.44e-01 | 8.24e-01 |
| REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | 18 | 5.42e-01 | 8.30e-02 | 8.24e-01 |
| REACTOME ACTIVATION OF RAC1 | 12 | 5.43e-01 | -1.02e-01 | 8.24e-01 |
| REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR4 | 26 | 5.44e-01 | 6.88e-02 | 8.24e-01 |
| REACTOME FORMATION OF XYLULOSE 5 PHOSPHATE | 5 | 5.44e-01 | 1.57e-01 | 8.24e-01 |
| REACTOME DEFECTIVE GALNT3 CAUSES HFTC | 16 | 5.44e-01 | -8.76e-02 | 8.24e-01 |
| REACTOME G PROTEIN BETA GAMMA SIGNALLING | 30 | 5.45e-01 | 6.39e-02 | 8.24e-01 |
| REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES | 12 | 5.46e-01 | 1.01e-01 | 8.24e-01 |
| REACTOME SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER | 54 | 5.46e-01 | 4.75e-02 | 8.24e-01 |
| REACTOME OPIOID SIGNALLING | 89 | 5.48e-01 | -3.69e-02 | 8.24e-01 |
| REACTOME SARS COV 2 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS | 12 | 5.48e-01 | -1.00e-01 | 8.24e-01 |
| REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION | 9 | 5.48e-01 | 1.16e-01 | 8.24e-01 |
| REACTOME ALPHA OXIDATION OF PHYTANATE | 6 | 5.48e-01 | -1.41e-01 | 8.24e-01 |
| REACTOME SIGNALING BY FGFR2 IN DISEASE | 42 | 5.48e-01 | 5.35e-02 | 8.24e-01 |
| REACTOME CD209 DC SIGN SIGNALING | 20 | 5.49e-01 | 7.75e-02 | 8.24e-01 |
| REACTOME ACTIVATION OF C3 AND C5 | 6 | 5.49e-01 | 1.41e-01 | 8.24e-01 |
| REACTOME FRUCTOSE CATABOLISM | 5 | 5.50e-01 | 1.54e-01 | 8.24e-01 |
| REACTOME REGULATION BY C FLIP | 11 | 5.50e-01 | -1.04e-01 | 8.24e-01 |
| REACTOME OVARIAN TUMOR DOMAIN PROTEASES | 36 | 5.50e-01 | -5.76e-02 | 8.24e-01 |
| REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS | 8 | 5.50e-01 | 1.22e-01 | 8.24e-01 |
| REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | 123 | 5.50e-01 | -3.12e-02 | 8.24e-01 |
| REACTOME PURINE CATABOLISM | 17 | 5.51e-01 | 8.36e-02 | 8.25e-01 |
| REACTOME NR1H2 AND NR1H3 MEDIATED SIGNALING | 46 | 5.52e-01 | 5.07e-02 | 8.25e-01 |
| REACTOME SYNTHESIS OF 12 EICOSATETRAENOIC ACID DERIVATIVES | 7 | 5.52e-01 | 1.30e-01 | 8.25e-01 |
| REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR4 | 14 | 5.54e-01 | -9.12e-02 | 8.25e-01 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS | 5 | 5.55e-01 | 1.53e-01 | 8.25e-01 |
| REACTOME DOPAMINE RECEPTORS | 5 | 5.55e-01 | 1.52e-01 | 8.25e-01 |
| REACTOME NEPHRIN FAMILY INTERACTIONS | 22 | 5.56e-01 | 7.26e-02 | 8.25e-01 |
| REACTOME ACTIVATED NTRK3 SIGNALS THROUGH PI3K | 6 | 5.56e-01 | -1.39e-01 | 8.25e-01 |
| REACTOME NUCLEAR ENVELOPE BREAKDOWN | 52 | 5.56e-01 | 4.72e-02 | 8.25e-01 |
| REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | 19 | 5.57e-01 | 7.77e-02 | 8.25e-01 |
| REACTOME OTHER INTERLEUKIN SIGNALING | 24 | 5.58e-01 | 6.91e-02 | 8.25e-01 |
| REACTOME MUCOPOLYSACCHARIDOSES | 10 | 5.58e-01 | -1.07e-01 | 8.25e-01 |
| REACTOME GLUCAGON TYPE LIGAND RECEPTORS | 32 | 5.59e-01 | 5.97e-02 | 8.25e-01 |
| REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | 14 | 5.60e-01 | -9.00e-02 | 8.25e-01 |
| REACTOME TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS | 43 | 5.60e-01 | 5.13e-02 | 8.25e-01 |
| REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION | 26 | 5.61e-01 | 6.59e-02 | 8.25e-01 |
| REACTOME FORMATION OF PARAXIAL MESODERM | 22 | 5.61e-01 | 7.16e-02 | 8.25e-01 |
| REACTOME ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT | 23 | 5.62e-01 | -6.99e-02 | 8.25e-01 |
| REACTOME LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX | 5 | 5.62e-01 | -1.50e-01 | 8.25e-01 |
| REACTOME ORGANIC CATION TRANSPORT | 10 | 5.63e-01 | -1.06e-01 | 8.25e-01 |
| REACTOME PI 3K CASCADE FGFR4 | 19 | 5.64e-01 | 7.64e-02 | 8.25e-01 |
| REACTOME NEGATIVE REGULATION OF ACTIVITY OF TFAP2 AP 2 FAMILY TRANSCRIPTION FACTORS | 10 | 5.65e-01 | -1.05e-01 | 8.25e-01 |
| REACTOME METABOLISM OF PORPHYRINS | 26 | 5.65e-01 | 6.52e-02 | 8.25e-01 |
| REACTOME ABACAVIR ADME | 9 | 5.66e-01 | 1.11e-01 | 8.25e-01 |
| REACTOME MATURATION OF SARS COV 2 SPIKE PROTEIN | 35 | 5.67e-01 | 5.59e-02 | 8.25e-01 |
| REACTOME NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 11 | 5.68e-01 | 9.96e-02 | 8.25e-01 |
| REACTOME MINERALOCORTICOID BIOSYNTHESIS | 6 | 5.68e-01 | -1.35e-01 | 8.25e-01 |
| REACTOME TRANSPORT AND SYNTHESIS OF PAPS | 6 | 5.68e-01 | 1.34e-01 | 8.25e-01 |
| REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | 31 | 5.69e-01 | 5.90e-02 | 8.25e-01 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES | 8 | 5.69e-01 | -1.16e-01 | 8.25e-01 |
| REACTOME RIPK1 MEDIATED REGULATED NECROSIS | 30 | 5.70e-01 | 6.00e-02 | 8.25e-01 |
| REACTOME RAF ACTIVATION | 33 | 5.71e-01 | -5.70e-02 | 8.25e-01 |
| REACTOME DEFECTS IN COBALAMIN B12 METABOLISM | 13 | 5.71e-01 | 9.08e-02 | 8.25e-01 |
| REACTOME VITAMIN B2 RIBOFLAVIN METABOLISM | 7 | 5.71e-01 | 1.24e-01 | 8.25e-01 |
| REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | 15 | 5.72e-01 | -8.44e-02 | 8.25e-01 |
| REACTOME CALCINEURIN ACTIVATES NFAT | 9 | 5.72e-01 | -1.09e-01 | 8.25e-01 |
| REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | 30 | 5.72e-01 | -5.96e-02 | 8.25e-01 |
| REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS | 21 | 5.72e-01 | -7.12e-02 | 8.25e-01 |
| REACTOME RHOC GTPASE CYCLE | 71 | 5.72e-01 | -3.88e-02 | 8.25e-01 |
| REACTOME CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE | 49 | 5.72e-01 | -4.66e-02 | 8.25e-01 |
| REACTOME SPHINGOLIPID METABOLISM | 84 | 5.73e-01 | 3.56e-02 | 8.25e-01 |
| REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | 11 | 5.73e-01 | 9.82e-02 | 8.25e-01 |
| REACTOME N GLYCAN TRIMMING AND ELONGATION IN THE CIS GOLGI | 5 | 5.73e-01 | 1.46e-01 | 8.25e-01 |
| REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | 13 | 5.73e-01 | 9.02e-02 | 8.25e-01 |
| REACTOME NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 11 | 5.74e-01 | 9.80e-02 | 8.25e-01 |
| REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | 16 | 5.74e-01 | 8.12e-02 | 8.25e-01 |
| REACTOME EPITHELIAL MESENCHYMAL TRANSITION EMT DURING GASTRULATION | 7 | 5.74e-01 | 1.23e-01 | 8.25e-01 |
| REACTOME ESTROGEN BIOSYNTHESIS | 6 | 5.77e-01 | 1.32e-01 | 8.27e-01 |
| REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | 11 | 5.77e-01 | -9.72e-02 | 8.27e-01 |
| REACTOME P2Y RECEPTORS | 9 | 5.78e-01 | 1.07e-01 | 8.28e-01 |
| REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | 7 | 5.79e-01 | 1.21e-01 | 8.28e-01 |
| REACTOME PLASMA LIPOPROTEIN ASSEMBLY | 19 | 5.79e-01 | 7.36e-02 | 8.28e-01 |
| REACTOME HDL CLEARANCE | 5 | 5.80e-01 | -1.43e-01 | 8.28e-01 |
| REACTOME SHC MEDIATED CASCADE FGFR4 | 19 | 5.82e-01 | 7.29e-02 | 8.30e-01 |
| REACTOME AQUAPORIN MEDIATED TRANSPORT | 51 | 5.82e-01 | -4.45e-02 | 8.30e-01 |
| REACTOME FGFR1 LIGAND BINDING AND ACTIVATION | 15 | 5.82e-01 | 8.20e-02 | 8.30e-01 |
| REACTOME EPHRIN SIGNALING | 17 | 5.84e-01 | -7.67e-02 | 8.30e-01 |
| REACTOME REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM | 11 | 5.84e-01 | 9.54e-02 | 8.30e-01 |
| REACTOME SPRY REGULATION OF FGF SIGNALING | 16 | 5.84e-01 | 7.90e-02 | 8.30e-01 |
| REACTOME GLYCOGEN SYNTHESIS | 13 | 5.84e-01 | 8.76e-02 | 8.30e-01 |
| REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | 10 | 5.85e-01 | 9.97e-02 | 8.31e-01 |
| REACTOME DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A | 5 | 5.87e-01 | 1.40e-01 | 8.32e-01 |
| REACTOME ACETYLCHOLINE REGULATES INSULIN SECRETION | 10 | 5.88e-01 | 9.90e-02 | 8.33e-01 |
| REACTOME RHOG GTPASE CYCLE | 71 | 5.89e-01 | -3.71e-02 | 8.34e-01 |
| REACTOME INTESTINAL ABSORPTION | 5 | 5.90e-01 | -1.39e-01 | 8.34e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST | 18 | 5.90e-01 | 7.34e-02 | 8.34e-01 |
| REACTOME REGULATION OF PTEN MRNA TRANSLATION | 9 | 5.91e-01 | 1.03e-01 | 8.35e-01 |
| REACTOME SYNTHESIS OF PIPS AT THE ER MEMBRANE | 5 | 5.93e-01 | 1.38e-01 | 8.37e-01 |
| REACTOME PEPTIDE HORMONE METABOLISM | 84 | 5.94e-01 | 3.36e-02 | 8.37e-01 |
| REACTOME MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS | 17 | 5.95e-01 | 7.45e-02 | 8.37e-01 |
| REACTOME BUDDING AND MATURATION OF HIV VIRION | 28 | 5.96e-01 | 5.79e-02 | 8.37e-01 |
| REACTOME PHOSPHORYLATION OF THE APC C | 20 | 5.99e-01 | 6.80e-02 | 8.37e-01 |
| REACTOME NEUROTOXICITY OF CLOSTRIDIUM TOXINS | 10 | 5.99e-01 | 9.61e-02 | 8.37e-01 |
| REACTOME PHYSIOLOGICAL FACTORS | 14 | 5.99e-01 | 8.12e-02 | 8.37e-01 |
| REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | 15 | 5.99e-01 | -7.83e-02 | 8.37e-01 |
| REACTOME INTEGRATION OF ENERGY METABOLISM | 105 | 5.99e-01 | -2.97e-02 | 8.37e-01 |
| REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2 | 13 | 5.99e-01 | 8.41e-02 | 8.37e-01 |
| REACTOMEMATURATION OF SARS COV 1 NUCLEOPROTEIN | 11 | 6.00e-01 | -9.14e-02 | 8.37e-01 |
| REACTOME COENZYME A BIOSYNTHESIS | 8 | 6.00e-01 | 1.07e-01 | 8.37e-01 |
| REACTOME NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION | 20 | 6.00e-01 | 6.78e-02 | 8.37e-01 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE | 5 | 6.00e-01 | 1.35e-01 | 8.37e-01 |
| REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG | 7 | 6.01e-01 | 1.14e-01 | 8.38e-01 |
| REACTOME DEPOLYMERISATION OF THE NUCLEAR LAMINA | 14 | 6.05e-01 | -7.99e-02 | 8.42e-01 |
| REACTOME HEME SIGNALING | 47 | 6.11e-01 | 4.29e-02 | 8.50e-01 |
| REACTOME NETRIN MEDIATED REPULSION SIGNALS | 8 | 6.12e-01 | -1.04e-01 | 8.50e-01 |
| REACTOME DEFECTIVE LFNG CAUSES SCDO3 | 5 | 6.12e-01 | -1.31e-01 | 8.50e-01 |
| REACTOME NTRK2 ACTIVATES RAC1 | 5 | 6.15e-01 | 1.30e-01 | 8.52e-01 |
| REACTOME INTERLEUKIN 6 FAMILY SIGNALING | 24 | 6.16e-01 | 5.92e-02 | 8.52e-01 |
| REACTOME SIGNALLING TO ERKS | 34 | 6.16e-01 | 4.97e-02 | 8.52e-01 |
| REACTOME PHASE II CONJUGATION OF COMPOUNDS | 102 | 6.17e-01 | -2.87e-02 | 8.52e-01 |
| REACTOME DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS | 14 | 6.17e-01 | 7.72e-02 | 8.52e-01 |
| REACTOME REPRESSION OF WNT TARGET GENES | 14 | 6.17e-01 | -7.71e-02 | 8.52e-01 |
| REACTOME TRANSLESION SYNTHESIS BY POLH | 19 | 6.18e-01 | 6.61e-02 | 8.52e-01 |
| REACTOME PROTON COUPLED MONOCARBOXYLATE TRANSPORT | 6 | 6.18e-01 | 1.18e-01 | 8.52e-01 |
| REACTOME NEUROTRANSMITTER RELEASE CYCLE | 48 | 6.19e-01 | 4.14e-02 | 8.53e-01 |
| REACTOME SIGNALING BY HEDGEHOG | 148 | 6.20e-01 | 2.36e-02 | 8.53e-01 |
| REACTOME PLASMA LIPOPROTEIN REMODELING | 33 | 6.20e-01 | -4.99e-02 | 8.53e-01 |
| REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE | 11 | 6.22e-01 | -8.59e-02 | 8.55e-01 |
| REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | 15 | 6.22e-01 | -7.35e-02 | 8.55e-01 |
| REACTOME NICOTINATE METABOLISM | 31 | 6.22e-01 | -5.11e-02 | 8.55e-01 |
| REACTOME ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING | 9 | 6.24e-01 | -9.43e-02 | 8.56e-01 |
| REACTOME INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE | 20 | 6.29e-01 | 6.25e-02 | 8.62e-01 |
| REACTOME REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION | 9 | 6.33e-01 | 9.19e-02 | 8.67e-01 |
| REACTOME RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS | 9 | 6.34e-01 | 9.18e-02 | 8.67e-01 |
| REACTOME METABOLISM OF CARBOHYDRATES | 279 | 6.35e-01 | -1.65e-02 | 8.68e-01 |
| REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | 20 | 6.35e-01 | 6.12e-02 | 8.68e-01 |
| REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING | 29 | 6.37e-01 | -5.07e-02 | 8.69e-01 |
| REACTOME PROPIONYL COA CATABOLISM | 5 | 6.37e-01 | 1.22e-01 | 8.69e-01 |
| REACTOME SIGNALING BY GPCR | 673 | 6.38e-01 | 1.06e-02 | 8.69e-01 |
| REACTOME PROLONGED ERK ACTIVATION EVENTS | 14 | 6.38e-01 | -7.26e-02 | 8.69e-01 |
| REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | 13 | 6.41e-01 | 7.48e-02 | 8.71e-01 |
| REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | 38 | 6.41e-01 | 4.37e-02 | 8.71e-01 |
| REACTOME WAX AND PLASMALOGEN BIOSYNTHESIS | 5 | 6.42e-01 | 1.20e-01 | 8.72e-01 |
| REACTOME ABACAVIR TRANSMEMBRANE TRANSPORT | 5 | 6.44e-01 | 1.19e-01 | 8.73e-01 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE | 5 | 6.45e-01 | -1.19e-01 | 8.73e-01 |
| REACTOME REGULATION OF NF KAPPA B SIGNALING | 17 | 6.45e-01 | 6.45e-02 | 8.73e-01 |
| REACTOME SIGNALLING TO P38 VIA RIT AND RIN | 5 | 6.45e-01 | -1.19e-01 | 8.73e-01 |
| REACTOME MUSCARINIC ACETYLCHOLINE RECEPTORS | 5 | 6.46e-01 | 1.19e-01 | 8.73e-01 |
| REACTOME INTERLEUKIN 23 SIGNALING | 9 | 6.47e-01 | 8.83e-02 | 8.73e-01 |
| REACTOME IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN | 5 | 6.47e-01 | -1.18e-01 | 8.73e-01 |
| REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING | 25 | 6.47e-01 | -5.29e-02 | 8.73e-01 |
| REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | 19 | 6.48e-01 | 6.04e-02 | 8.73e-01 |
| REACTOME INTRAFLAGELLAR TRANSPORT | 50 | 6.48e-01 | -3.73e-02 | 8.73e-01 |
| REACTOME SIGNALING BY ERBB4 | 57 | 6.49e-01 | 3.49e-02 | 8.73e-01 |
| REACTOME RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION | 8 | 6.50e-01 | -9.27e-02 | 8.73e-01 |
| REACTOME SIGNALING BY PDGF | 57 | 6.50e-01 | 3.47e-02 | 8.73e-01 |
| REACTOME LDL CLEARANCE | 19 | 6.50e-01 | 6.01e-02 | 8.73e-01 |
| REACTOME TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION | 5 | 6.52e-01 | 1.17e-01 | 8.74e-01 |
| REACTOME CHYLOMICRON ASSEMBLY | 10 | 6.52e-01 | -8.24e-02 | 8.74e-01 |
| REACTOME HSF1 ACTIVATION | 29 | 6.54e-01 | -4.81e-02 | 8.76e-01 |
| REACTOME SIGNALING BY VEGF | 102 | 6.55e-01 | 2.56e-02 | 8.77e-01 |
| REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION | 35 | 6.56e-01 | 4.35e-02 | 8.77e-01 |
| REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION | 32 | 6.58e-01 | 4.51e-02 | 8.79e-01 |
| REACTOME ACTIVATION OF RAS IN B CELLS | 5 | 6.59e-01 | 1.14e-01 | 8.79e-01 |
| REACTOME SYNTHESIS OF 15 EICOSATETRAENOIC ACID DERIVATIVES | 6 | 6.60e-01 | 1.04e-01 | 8.79e-01 |
| REACTOME HYDROLYSIS OF LPC | 9 | 6.60e-01 | -8.47e-02 | 8.79e-01 |
| REACTOME ACYL CHAIN REMODELLING OF PI | 17 | 6.61e-01 | -6.15e-02 | 8.80e-01 |
| REACTOME SIGNALING BY MRAS COMPLEX MUTANTS | 7 | 6.62e-01 | 9.55e-02 | 8.80e-01 |
| REACTOME HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR IN THE PRESENCE OF LIGAND | 55 | 6.62e-01 | 3.40e-02 | 8.80e-01 |
| REACTOME SIGNAL TRANSDUCTION BY L1 | 20 | 6.63e-01 | -5.63e-02 | 8.80e-01 |
| REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 44 | 6.63e-01 | 3.80e-02 | 8.80e-01 |
| REACTOME RAC2 GTPASE CYCLE | 81 | 6.63e-01 | 2.80e-02 | 8.80e-01 |
| REACTOME ACYL CHAIN REMODELLING OF PE | 29 | 6.65e-01 | -4.65e-02 | 8.80e-01 |
| REACTOME REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS | 14 | 6.65e-01 | -6.67e-02 | 8.80e-01 |
| REACTOME COMMON PATHWAY OF FIBRIN CLOT FORMATION | 21 | 6.66e-01 | 5.45e-02 | 8.80e-01 |
| REACTOME PLATELET HOMEOSTASIS | 85 | 6.66e-01 | 2.71e-02 | 8.80e-01 |
| REACTOME EARLY SARS COV 2 INFECTION EVENTS | 34 | 6.66e-01 | -4.27e-02 | 8.80e-01 |
| REACTOME CA2 ACTIVATED K CHANNELS | 9 | 6.67e-01 | -8.27e-02 | 8.80e-01 |
| REACTOME FGFR3B LIGAND BINDING AND ACTIVATION | 7 | 6.67e-01 | 9.38e-02 | 8.80e-01 |
| REACTOME GASTRULATION | 49 | 6.68e-01 | 3.54e-02 | 8.80e-01 |
| REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING | 6 | 6.68e-01 | -1.01e-01 | 8.80e-01 |
| REACTOME TRNA AMINOACYLATION | 40 | 6.69e-01 | 3.91e-02 | 8.80e-01 |
| REACTOME ERBB2 REGULATES CELL MOTILITY | 15 | 6.70e-01 | -6.36e-02 | 8.81e-01 |
| REACTOME PI3K EVENTS IN ERBB2 SIGNALING | 16 | 6.71e-01 | 6.13e-02 | 8.81e-01 |
| REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING | 30 | 6.71e-01 | 4.48e-02 | 8.81e-01 |
| REACTOME PTK6 REGULATES CELL CYCLE | 6 | 6.72e-01 | 9.98e-02 | 8.81e-01 |
| REACTOME RHO GTPASES ACTIVATE WASPS AND WAVES | 34 | 6.72e-01 | 4.19e-02 | 8.81e-01 |
| REACTOME SIGNALING BY WNT IN CANCER | 32 | 6.73e-01 | -4.31e-02 | 8.81e-01 |
| REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS | 16 | 6.73e-01 | 6.08e-02 | 8.81e-01 |
| REACTOME TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS | 55 | 6.74e-01 | 3.28e-02 | 8.81e-01 |
| REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | 63 | 6.76e-01 | -3.05e-02 | 8.81e-01 |
| REACTOME TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE | 20 | 6.77e-01 | -5.39e-02 | 8.81e-01 |
| REACTOME REGULATION OF LIPID METABOLISM BY PPARALPHA | 115 | 6.77e-01 | 2.25e-02 | 8.81e-01 |
| REACTOME HIV ELONGATION ARREST AND RECOVERY | 33 | 6.77e-01 | 4.19e-02 | 8.81e-01 |
| REACTOME CHYLOMICRON CLEARANCE | 5 | 6.77e-01 | -1.07e-01 | 8.81e-01 |
| REACTOME ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE | 9 | 6.78e-01 | -8.00e-02 | 8.81e-01 |
| REACTOME DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE | 30 | 6.78e-01 | 4.38e-02 | 8.81e-01 |
| REACTOME REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION | 84 | 6.79e-01 | -2.62e-02 | 8.82e-01 |
| REACTOME PYRIMIDINE SALVAGE | 10 | 6.81e-01 | -7.51e-02 | 8.83e-01 |
| REACTOME LATE ENDOSOMAL MICROAUTOPHAGY | 33 | 6.82e-01 | 4.13e-02 | 8.83e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4 | 33 | 6.82e-01 | -4.12e-02 | 8.83e-01 |
| REACTOME PTK6 PROMOTES HIF1A STABILIZATION | 6 | 6.82e-01 | -9.66e-02 | 8.83e-01 |
| REACTOME INTEGRIN CELL SURFACE INTERACTIONS | 83 | 6.83e-01 | -2.59e-02 | 8.83e-01 |
| REACTOME TRP CHANNELS | 27 | 6.83e-01 | -4.54e-02 | 8.83e-01 |
| REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM | 23 | 6.85e-01 | 4.88e-02 | 8.83e-01 |
| REACTOME NUCLEOTIDE SALVAGE | 21 | 6.85e-01 | 5.11e-02 | 8.83e-01 |
| REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX | 39 | 6.85e-01 | -3.75e-02 | 8.83e-01 |
| REACTOME DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS | 25 | 6.86e-01 | 4.68e-02 | 8.83e-01 |
| REACTOME UPTAKE AND ACTIONS OF BACTERIAL TOXINS | 28 | 6.86e-01 | 4.41e-02 | 8.83e-01 |
| REACTOME BETA OXIDATION OF PRISTANOYL COA | 9 | 6.86e-01 | 7.77e-02 | 8.83e-01 |
| REACTOME BIOLOGICAL OXIDATIONS | 210 | 6.88e-01 | -1.61e-02 | 8.85e-01 |
| REACTOME SUMOYLATION OF UBIQUITINYLATION PROTEINS | 39 | 6.89e-01 | 3.70e-02 | 8.85e-01 |
| REACTOME TIGHT JUNCTION INTERACTIONS | 29 | 6.90e-01 | -4.28e-02 | 8.86e-01 |
| REACTOME CA2 PATHWAY | 62 | 6.92e-01 | 2.91e-02 | 8.87e-01 |
| REACTOME PRE NOTCH PROCESSING IN GOLGI | 18 | 6.92e-01 | 5.39e-02 | 8.87e-01 |
| REACTOME SIGNALING BY FGFR2 IIIA TM | 19 | 6.93e-01 | -5.24e-02 | 8.87e-01 |
| REACTOME PHASE 3 RAPID REPOLARISATION | 8 | 6.94e-01 | -8.04e-02 | 8.88e-01 |
| REACTOME RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR | 19 | 6.95e-01 | -5.19e-02 | 8.89e-01 |
| REACTOME SYNTHESIS OF UDP N ACETYL GLUCOSAMINE | 7 | 6.98e-01 | 8.47e-02 | 8.91e-01 |
| REACTOME SIGNALING BY NOTCH3 | 48 | 6.98e-01 | 3.24e-02 | 8.91e-01 |
| REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY DVL INTERACTING PROTEINS | 5 | 6.98e-01 | 1.00e-01 | 8.91e-01 |
| REACTOME DISORDERS OF TRANSMEMBRANE TRANSPORTERS | 170 | 6.99e-01 | 1.72e-02 | 8.91e-01 |
| REACTOME RAS PROCESSING | 22 | 7.01e-01 | 4.73e-02 | 8.92e-01 |
| REACTOME POST TRANSCRIPTIONAL SILENCING BY SMALL RNAS | 7 | 7.02e-01 | 8.36e-02 | 8.92e-01 |
| REACTOME MAPK1 ERK2 ACTIVATION | 9 | 7.02e-01 | 7.37e-02 | 8.92e-01 |
| REACTOME SIGNALING BY FGFR4 | 40 | 7.02e-01 | 3.49e-02 | 8.92e-01 |
| REACTOME CARGO CONCENTRATION IN THE ER | 32 | 7.03e-01 | 3.90e-02 | 8.92e-01 |
| REACTOME BASIGIN INTERACTIONS | 24 | 7.06e-01 | -4.45e-02 | 8.96e-01 |
| REACTOME SOS MEDIATED SIGNALLING | 7 | 7.07e-01 | 8.19e-02 | 8.96e-01 |
| REACTOME AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY | 8 | 7.08e-01 | 7.65e-02 | 8.96e-01 |
| REACTOME COBALAMIN CBL METABOLISM | 7 | 7.08e-01 | 8.18e-02 | 8.96e-01 |
| REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | 15 | 7.10e-01 | 5.55e-02 | 8.96e-01 |
| REACTOME MTOR SIGNALLING | 40 | 7.10e-01 | 3.39e-02 | 8.96e-01 |
| REACTOME UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION | 19 | 7.10e-01 | -4.92e-02 | 8.96e-01 |
| REACTOME CITRIC ACID CYCLE TCA CYCLE | 21 | 7.11e-01 | 4.68e-02 | 8.96e-01 |
| REACTOME MET ACTIVATES PTPN11 | 5 | 7.11e-01 | 9.56e-02 | 8.96e-01 |
| REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | 16 | 7.13e-01 | 5.32e-02 | 8.96e-01 |
| REACTOME SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL | 25 | 7.13e-01 | -4.25e-02 | 8.96e-01 |
| REACTOME EGFR TRANSACTIVATION BY GASTRIN | 9 | 7.14e-01 | 7.06e-02 | 8.96e-01 |
| REACTOME THE PHOTOTRANSDUCTION CASCADE | 32 | 7.14e-01 | 3.74e-02 | 8.96e-01 |
| REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | 24 | 7.14e-01 | 4.32e-02 | 8.96e-01 |
| REACTOME HISTIDINE CATABOLISM | 8 | 7.15e-01 | -7.46e-02 | 8.96e-01 |
| REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN | 32 | 7.15e-01 | 3.73e-02 | 8.96e-01 |
| REACTOME METABOLISM OF COFACTORS | 19 | 7.15e-01 | 4.83e-02 | 8.96e-01 |
| REACTOME IKBA VARIANT LEADS TO EDA ID | 6 | 7.15e-01 | -8.60e-02 | 8.96e-01 |
| REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | 19 | 7.17e-01 | 4.81e-02 | 8.97e-01 |
| REACTOME NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 25 | 7.20e-01 | 4.14e-02 | 8.99e-01 |
| REACTOME NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY | 6 | 7.20e-01 | -8.45e-02 | 8.99e-01 |
| REACTOME REGULATION OF NPAS4 GENE TRANSCRIPTION | 5 | 7.21e-01 | 9.23e-02 | 8.99e-01 |
| REACTOME CAMK IV MEDIATED PHOSPHORYLATION OF CREB | 10 | 7.21e-01 | -6.52e-02 | 8.99e-01 |
| REACTOME PYROPTOSIS | 27 | 7.21e-01 | -3.96e-02 | 8.99e-01 |
| REACTOME INTERLEUKIN 18 SIGNALING | 8 | 7.22e-01 | -7.27e-02 | 8.99e-01 |
| REACTOME DISEASES ASSOCIATED WITH SURFACTANT METABOLISM | 9 | 7.23e-01 | 6.83e-02 | 8.99e-01 |
| REACTOME GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION | 30 | 7.23e-01 | 3.75e-02 | 8.99e-01 |
| REACTOME ZINC TRANSPORTERS | 15 | 7.24e-01 | -5.27e-02 | 8.99e-01 |
| REACTOME ADRENOCEPTORS | 9 | 7.25e-01 | -6.77e-02 | 9.01e-01 |
| REACTOME DEATH RECEPTOR SIGNALING | 143 | 7.28e-01 | -1.69e-02 | 9.03e-01 |
| REACTOME REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA | 15 | 7.29e-01 | 5.17e-02 | 9.03e-01 |
| REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS | 33 | 7.29e-01 | 3.48e-02 | 9.03e-01 |
| REACTOME RHOBTB1 GTPASE CYCLE | 22 | 7.31e-01 | 4.24e-02 | 9.05e-01 |
| REACTOME PI METABOLISM | 79 | 7.32e-01 | 2.23e-02 | 9.05e-01 |
| REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF | 53 | 7.32e-01 | -2.72e-02 | 9.05e-01 |
| REACTOME TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS | 29 | 7.33e-01 | 3.66e-02 | 9.06e-01 |
| REACTOME RUNX3 REGULATES BCL2L11 BIM TRANSCRIPTION | 5 | 7.34e-01 | -8.77e-02 | 9.06e-01 |
| REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | 11 | 7.34e-01 | -5.91e-02 | 9.06e-01 |
| REACTOME EPH EPHRIN MEDIATED REPULSION OF CELLS | 50 | 7.35e-01 | -2.77e-02 | 9.06e-01 |
| REACTOME SYNTHESIS OF GDP MANNOSE | 5 | 7.38e-01 | 8.64e-02 | 9.09e-01 |
| REACTOME ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS | 11 | 7.39e-01 | -5.80e-02 | 9.09e-01 |
| REACTOME METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES | 33 | 7.40e-01 | -3.34e-02 | 9.09e-01 |
| REACTOME RAP1 SIGNALLING | 16 | 7.41e-01 | 4.78e-02 | 9.09e-01 |
| REACTOME ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS | 20 | 7.41e-01 | 4.27e-02 | 9.09e-01 |
| REACTOME PHENYLALANINE METABOLISM | 6 | 7.43e-01 | -7.74e-02 | 9.09e-01 |
| REACTOME ETHANOL OXIDATION | 12 | 7.43e-01 | 5.47e-02 | 9.09e-01 |
| REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | 11 | 7.43e-01 | 5.71e-02 | 9.09e-01 |
| REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS | 15 | 7.44e-01 | 4.88e-02 | 9.09e-01 |
| REACTOME METABOLISM OF FOLATE AND PTERINES | 17 | 7.44e-01 | -4.58e-02 | 9.09e-01 |
| REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL | 13 | 7.45e-01 | -5.22e-02 | 9.09e-01 |
| REACTOME G2 M DNA REPLICATION CHECKPOINT | 5 | 7.45e-01 | -8.40e-02 | 9.09e-01 |
| REACTOME LATE SARS COV 2 INFECTION EVENTS | 67 | 7.47e-01 | -2.28e-02 | 9.09e-01 |
| REACTOME NEUROTRANSMITTER CLEARANCE | 9 | 7.47e-01 | 6.22e-02 | 9.09e-01 |
| REACTOME MISCELLANEOUS SUBSTRATES | 12 | 7.47e-01 | 5.39e-02 | 9.09e-01 |
| REACTOME MAPK3 ERK1 ACTIVATION | 10 | 7.47e-01 | 5.88e-02 | 9.09e-01 |
| REACTOME TYSND1 CLEAVES PEROXISOMAL PROTEINS | 7 | 7.48e-01 | 7.02e-02 | 9.09e-01 |
| REACTOME POLYMERASE SWITCHING | 13 | 7.48e-01 | 5.14e-02 | 9.09e-01 |
| REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE GIP | 12 | 7.48e-01 | -5.35e-02 | 9.09e-01 |
| REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | 91 | 7.51e-01 | 1.93e-02 | 9.12e-01 |
| REACTOME SULFUR AMINO ACID METABOLISM | 27 | 7.52e-01 | -3.52e-02 | 9.12e-01 |
| REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION | 20 | 7.52e-01 | 4.08e-02 | 9.12e-01 |
| REACTOME UBIQUINOL BIOSYNTHESIS | 8 | 7.52e-01 | -6.44e-02 | 9.12e-01 |
| REACTOME ACYL CHAIN REMODELING OF DAG AND TAG | 5 | 7.56e-01 | 8.03e-02 | 9.15e-01 |
| REACTOME RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION | 6 | 7.56e-01 | 7.33e-02 | 9.15e-01 |
| REACTOME MATURATION OF SARS COV 1 SPIKE PROTEIN | 5 | 7.58e-01 | 7.97e-02 | 9.16e-01 |
| REACTOME THYROXINE BIOSYNTHESIS | 10 | 7.58e-01 | -5.63e-02 | 9.16e-01 |
| REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS | 83 | 7.59e-01 | 1.95e-02 | 9.16e-01 |
| REACTOME GLUCOCORTICOID BIOSYNTHESIS | 10 | 7.60e-01 | -5.58e-02 | 9.16e-01 |
| REACTOME DERMATAN SULFATE BIOSYNTHESIS | 10 | 7.60e-01 | 5.57e-02 | 9.16e-01 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FYN | 7 | 7.60e-01 | 6.65e-02 | 9.16e-01 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING | 5 | 7.61e-01 | -7.85e-02 | 9.16e-01 |
| REACTOME PP2A MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS | 6 | 7.61e-01 | -7.16e-02 | 9.16e-01 |
| REACTOME ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS | 41 | 7.63e-01 | -2.72e-02 | 9.17e-01 |
| REACTOME OTHER SEMAPHORIN INTERACTIONS | 18 | 7.63e-01 | -4.10e-02 | 9.17e-01 |
| REACTOME GLUCONEOGENESIS | 33 | 7.65e-01 | 3.01e-02 | 9.17e-01 |
| REACTOME RRNA MODIFICATION IN THE MITOCHONDRION | 6 | 7.65e-01 | 7.05e-02 | 9.17e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION | 12 | 7.65e-01 | 4.98e-02 | 9.17e-01 |
| REACTOME INFLAMMASOMES | 21 | 7.65e-01 | -3.76e-02 | 9.17e-01 |
| REACTOME CREB PHOSPHORYLATION | 6 | 7.66e-01 | 7.01e-02 | 9.17e-01 |
| REACTOME FGFR2C LIGAND BINDING AND ACTIVATION | 12 | 7.67e-01 | 4.95e-02 | 9.17e-01 |
| REACTOME SIGNALING BY RNF43 MUTANTS | 8 | 7.68e-01 | 6.02e-02 | 9.18e-01 |
| REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE | 5 | 7.68e-01 | 7.60e-02 | 9.18e-01 |
| REACTOME PASSIVE TRANSPORT BY AQUAPORINS | 13 | 7.69e-01 | -4.70e-02 | 9.18e-01 |
| REACTOME BETA CATENIN PHOSPHORYLATION CASCADE | 16 | 7.70e-01 | -4.22e-02 | 9.18e-01 |
| REACTOME SODIUM PROTON EXCHANGERS | 7 | 7.70e-01 | 6.37e-02 | 9.18e-01 |
| REACTOME CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION | 24 | 7.74e-01 | 3.39e-02 | 9.21e-01 |
| REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK | 17 | 7.76e-01 | 3.99e-02 | 9.23e-01 |
| REACTOME ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS | 10 | 7.76e-01 | 5.19e-02 | 9.23e-01 |
| REACTOME SENSORY PERCEPTION OF SALTY TASTE | 6 | 7.80e-01 | -6.58e-02 | 9.27e-01 |
| REACTOME REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS | 7 | 7.84e-01 | 5.99e-02 | 9.28e-01 |
| REACTOME INTEGRIN SIGNALING | 27 | 7.85e-01 | 3.04e-02 | 9.28e-01 |
| REACTOME PHOSPHOLIPID METABOLISM | 201 | 7.86e-01 | -1.11e-02 | 9.28e-01 |
| REACTOME NONCANONICAL ACTIVATION OF NOTCH3 | 8 | 7.86e-01 | -5.55e-02 | 9.28e-01 |
| REACTOME VASOPRESSIN LIKE RECEPTORS | 5 | 7.86e-01 | 7.01e-02 | 9.28e-01 |
| REACTOME GLYCEROPHOSPHOLIPID CATABOLISM | 7 | 7.87e-01 | -5.91e-02 | 9.28e-01 |
| REACTOME ARMS MEDIATED ACTIVATION | 7 | 7.87e-01 | -5.90e-02 | 9.28e-01 |
| REACTOME ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY | 10 | 7.87e-01 | -4.93e-02 | 9.28e-01 |
| REACTOME SERINE BIOSYNTHESIS | 9 | 7.88e-01 | -5.19e-02 | 9.28e-01 |
| REACTOME G ALPHA S SIGNALLING EVENTS | 155 | 7.88e-01 | -1.25e-02 | 9.28e-01 |
| REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY | 5 | 7.88e-01 | -6.93e-02 | 9.28e-01 |
| REACTOME RHOF GTPASE CYCLE | 40 | 7.90e-01 | -2.44e-02 | 9.28e-01 |
| REACTOME ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION | 28 | 7.90e-01 | 2.91e-02 | 9.28e-01 |
| REACTOME NUCLEAR SIGNALING BY ERBB4 | 32 | 7.90e-01 | -2.72e-02 | 9.28e-01 |
| REACTOME DIGESTION OF DIETARY CARBOHYDRATE | 6 | 7.91e-01 | -6.23e-02 | 9.28e-01 |
| REACTOME SIGNALING BY NOTCH1 T 7 9 NOTCH1 M1580 K2555 TRANSLOCATION MUTANT | 7 | 7.92e-01 | 5.76e-02 | 9.28e-01 |
| REACTOME SCAVENGING BY CLASS B RECEPTORS | 6 | 7.92e-01 | 6.22e-02 | 9.28e-01 |
| REACTOME LONG TERM POTENTIATION | 22 | 7.92e-01 | -3.24e-02 | 9.28e-01 |
| REACTOME G ALPHA Z SIGNALLING EVENTS | 48 | 7.92e-01 | 2.20e-02 | 9.28e-01 |
| REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | 26 | 7.92e-01 | 2.98e-02 | 9.28e-01 |
| REACTOME SIGNALING BY MET | 78 | 7.93e-01 | -1.72e-02 | 9.28e-01 |
| REACTOME TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY | 30 | 7.97e-01 | 2.71e-02 | 9.32e-01 |
| REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | 11 | 8.02e-01 | -4.37e-02 | 9.36e-01 |
| REACTOME INOSITOL PHOSPHATE METABOLISM | 45 | 8.03e-01 | -2.15e-02 | 9.36e-01 |
| REACTOME N GLYCAN ANTENNAE ELONGATION | 15 | 8.04e-01 | -3.69e-02 | 9.36e-01 |
| REACTOME IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS | 17 | 8.05e-01 | -3.46e-02 | 9.36e-01 |
| REACTOME HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS | 9 | 8.05e-01 | 4.75e-02 | 9.36e-01 |
| REACTOME ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS | 7 | 8.05e-01 | 5.38e-02 | 9.36e-01 |
| REACTOME GDP FUCOSE BIOSYNTHESIS | 6 | 8.06e-01 | 5.80e-02 | 9.36e-01 |
| REACTOME RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION | 6 | 8.07e-01 | 5.77e-02 | 9.36e-01 |
| REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | 17 | 8.07e-01 | 3.43e-02 | 9.36e-01 |
| REACTOME SYNTHESIS OF PA | 38 | 8.07e-01 | 2.29e-02 | 9.36e-01 |
| REACTOME RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK | 47 | 8.07e-01 | 2.06e-02 | 9.36e-01 |
| REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | 48 | 8.08e-01 | -2.02e-02 | 9.37e-01 |
| REACTOME TELOMERE C STRAND SYNTHESIS INITIATION | 12 | 8.09e-01 | 4.03e-02 | 9.37e-01 |
| REACTOME DARPP 32 EVENTS | 24 | 8.11e-01 | -2.82e-02 | 9.39e-01 |
| REACTOME GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION | 14 | 8.13e-01 | 3.66e-02 | 9.40e-01 |
| REACTOME DNA DAMAGE REVERSAL | 8 | 8.14e-01 | 4.80e-02 | 9.42e-01 |
| REACTOME THE ACTIVATION OF ARYLSULFATASES | 8 | 8.15e-01 | 4.77e-02 | 9.42e-01 |
| REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV 1 INFECTION | 5 | 8.16e-01 | -6.00e-02 | 9.42e-01 |
| REACTOME REGULATION OF INSULIN SECRETION | 77 | 8.17e-01 | 1.52e-02 | 9.42e-01 |
| REACTOME ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY | 5 | 8.18e-01 | -5.96e-02 | 9.42e-01 |
| REACTOME THE NLRP3 INFLAMMASOME | 16 | 8.18e-01 | 3.32e-02 | 9.42e-01 |
| REACTOME ARACHIDONATE PRODUCTION FROM DAG | 5 | 8.19e-01 | 5.91e-02 | 9.42e-01 |
| REACTOME LRR FLII INTERACTING PROTEIN 1 LRRFIP1 ACTIVATES TYPE I IFN PRODUCTION | 5 | 8.19e-01 | 5.90e-02 | 9.42e-01 |
| REACTOME CYTOCHROME C MEDIATED APOPTOTIC RESPONSE | 12 | 8.19e-01 | 3.81e-02 | 9.42e-01 |
| REACTOME LGI ADAM INTERACTIONS | 14 | 8.19e-01 | 3.52e-02 | 9.42e-01 |
| REACTOME SIGNALING BY ERBB2 ECD MUTANTS | 16 | 8.21e-01 | 3.26e-02 | 9.43e-01 |
| REACTOME SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL | 8 | 8.23e-01 | -4.56e-02 | 9.44e-01 |
| REACTOME ARACHIDONIC ACID METABOLISM | 57 | 8.24e-01 | 1.70e-02 | 9.44e-01 |
| REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION | 74 | 8.24e-01 | -1.49e-02 | 9.44e-01 |
| REACTOME FORMATION OF APOPTOSOME | 10 | 8.25e-01 | 4.04e-02 | 9.44e-01 |
| REACTOME RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA | 7 | 8.25e-01 | 4.82e-02 | 9.44e-01 |
| REACTOME SUPPRESSION OF APOPTOSIS | 7 | 8.27e-01 | -4.78e-02 | 9.45e-01 |
| REACTOME RHOH GTPASE CYCLE | 37 | 8.27e-01 | -2.08e-02 | 9.45e-01 |
| REACTOME NADE MODULATES DEATH SIGNALLING | 5 | 8.28e-01 | -5.62e-02 | 9.45e-01 |
| REACTOME TNFR1 INDUCED PROAPOPTOTIC SIGNALING | 23 | 8.28e-01 | 2.61e-02 | 9.45e-01 |
| REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION | 32 | 8.30e-01 | 2.19e-02 | 9.47e-01 |
| REACTOME PTK6 EXPRESSION | 5 | 8.32e-01 | -5.48e-02 | 9.48e-01 |
| REACTOME PARACETAMOL ADME | 26 | 8.34e-01 | 2.37e-02 | 9.49e-01 |
| REACTOME RHO GTPASES ACTIVATE PAKS | 19 | 8.35e-01 | -2.76e-02 | 9.49e-01 |
| REACTOME METABOLISM OF STEROIDS | 150 | 8.36e-01 | -9.82e-03 | 9.49e-01 |
| REACTOME ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS | 5 | 8.37e-01 | -5.32e-02 | 9.49e-01 |
| REACTOME FOXO MEDIATED TRANSCRIPTION | 65 | 8.37e-01 | -1.48e-02 | 9.49e-01 |
| REACTOME SYNTHESIS OF PE | 13 | 8.37e-01 | -3.30e-02 | 9.49e-01 |
| REACTOME RRNA PROCESSING IN THE MITOCHONDRION | 9 | 8.38e-01 | 3.94e-02 | 9.49e-01 |
| REACTOME REGULATION OF FZD BY UBIQUITINATION | 21 | 8.38e-01 | 2.57e-02 | 9.49e-01 |
| REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE | 8 | 8.38e-01 | 4.16e-02 | 9.49e-01 |
| REACTOME CELLULAR RESPONSE TO HEAT STRESS | 99 | 8.41e-01 | 1.17e-02 | 9.51e-01 |
| REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL | 12 | 8.41e-01 | 3.34e-02 | 9.51e-01 |
| REACTOME CONSTITUTIVE SIGNALING BY EGFRVIII | 15 | 8.41e-01 | 2.99e-02 | 9.51e-01 |
| REACTOME INTRA GOLGI TRAFFIC | 43 | 8.43e-01 | 1.75e-02 | 9.52e-01 |
| REACTOME BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA | 5 | 8.45e-01 | -5.06e-02 | 9.53e-01 |
| REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | 17 | 8.47e-01 | 2.71e-02 | 9.55e-01 |
| REACTOME VITAMIN C ASCORBATE METABOLISM | 8 | 8.48e-01 | 3.92e-02 | 9.55e-01 |
| REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES | 15 | 8.48e-01 | -2.85e-02 | 9.55e-01 |
| REACTOME NUCLEOTIDE CATABOLISM | 35 | 8.49e-01 | -1.86e-02 | 9.55e-01 |
| REACTOME RIP MEDIATED NFKB ACTIVATION VIA ZBP1 | 16 | 8.49e-01 | 2.75e-02 | 9.55e-01 |
| REACTOME MIRO GTPASE CYCLE | 8 | 8.50e-01 | 3.87e-02 | 9.55e-01 |
| REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | 36 | 8.51e-01 | -1.80e-02 | 9.56e-01 |
| REACTOME PHASE 1 INACTIVATION OF FAST NA CHANNELS | 6 | 8.52e-01 | -4.41e-02 | 9.56e-01 |
| REACTOME PROTEIN METHYLATION | 17 | 8.53e-01 | -2.60e-02 | 9.56e-01 |
| REACTOME MRNA CAPPING | 28 | 8.54e-01 | 2.01e-02 | 9.56e-01 |
| REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK | 28 | 8.54e-01 | -2.01e-02 | 9.56e-01 |
| REACTOME ELASTIC FIBRE FORMATION | 44 | 8.54e-01 | -1.60e-02 | 9.56e-01 |
| REACTOME EPH EPHRIN SIGNALING | 90 | 8.55e-01 | -1.11e-02 | 9.57e-01 |
| REACTOME LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME | 11 | 8.57e-01 | 3.15e-02 | 9.57e-01 |
| REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD4 | 15 | 8.57e-01 | 2.68e-02 | 9.57e-01 |
| REACTOME ONCOGENIC MAPK SIGNALING | 79 | 8.58e-01 | 1.17e-02 | 9.57e-01 |
| REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS | 6 | 8.60e-01 | -4.15e-02 | 9.58e-01 |
| REACTOME LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS | 19 | 8.60e-01 | 2.33e-02 | 9.58e-01 |
| REACTOME EGFR INTERACTS WITH PHOSPHOLIPASE C GAMMA | 9 | 8.61e-01 | -3.38e-02 | 9.58e-01 |
| REACTOME RHOU GTPASE CYCLE | 37 | 8.62e-01 | 1.65e-02 | 9.58e-01 |
| REACTOME RUNX3 REGULATES WNT SIGNALING | 8 | 8.62e-01 | -3.55e-02 | 9.58e-01 |
| REACTOME FGFR2 ALTERNATIVE SPLICING | 27 | 8.62e-01 | -1.93e-02 | 9.58e-01 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING | 6 | 8.64e-01 | 4.04e-02 | 9.58e-01 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING | 5 | 8.64e-01 | -4.42e-02 | 9.58e-01 |
| REACTOME FATTY ACIDS | 15 | 8.65e-01 | 2.53e-02 | 9.58e-01 |
| REACTOME TACHYKININ RECEPTORS BIND TACHYKININS | 5 | 8.65e-01 | -4.37e-02 | 9.58e-01 |
| REACTOME REGULATED NECROSIS | 57 | 8.67e-01 | 1.28e-02 | 9.58e-01 |
| REACTOME RHOT1 GTPASE CYCLE | 5 | 8.67e-01 | -4.31e-02 | 9.58e-01 |
| REACTOME MET ACTIVATES PI3K AKT SIGNALING | 6 | 8.68e-01 | -3.92e-02 | 9.58e-01 |
| REACTOME SEMA3A PAK DEPENDENT AXON REPULSION | 14 | 8.68e-01 | 2.56e-02 | 9.58e-01 |
| REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | 11 | 8.68e-01 | 2.89e-02 | 9.58e-01 |
| REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX | 32 | 8.68e-01 | 1.69e-02 | 9.58e-01 |
| REACTOME SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA PHE | 6 | 8.69e-01 | 3.90e-02 | 9.58e-01 |
| REACTOME FBXW7 MUTANTS AND NOTCH1 IN CANCER | 5 | 8.70e-01 | 4.21e-02 | 9.58e-01 |
| REACTOME SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS | 43 | 8.71e-01 | 1.44e-02 | 9.58e-01 |
| REACTOME TRAIL SIGNALING | 8 | 8.71e-01 | -3.31e-02 | 9.58e-01 |
| REACTOME PENTOSE PHOSPHATE PATHWAY | 12 | 8.71e-01 | 2.70e-02 | 9.58e-01 |
| REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | 8 | 8.72e-01 | 3.30e-02 | 9.58e-01 |
| REACTOME ORGANIC ANION TRANSPORT | 5 | 8.72e-01 | -4.16e-02 | 9.58e-01 |
| REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE | 52 | 8.73e-01 | 1.29e-02 | 9.58e-01 |
| REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS | 14 | 8.74e-01 | 2.45e-02 | 9.58e-01 |
| REACTOME GRB7 EVENTS IN ERBB2 SIGNALING | 5 | 8.74e-01 | 4.09e-02 | 9.58e-01 |
| REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | 18 | 8.74e-01 | -2.15e-02 | 9.58e-01 |
| REACTOME INTERLEUKIN 37 SIGNALING | 20 | 8.74e-01 | -2.04e-02 | 9.58e-01 |
| REACTOME SARS COV 1 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS | 16 | 8.77e-01 | 2.24e-02 | 9.59e-01 |
| REACTOME PYRUVATE METABOLISM | 29 | 8.77e-01 | -1.66e-02 | 9.59e-01 |
| REACTOME GLYCOGEN METABOLISM | 22 | 8.78e-01 | 1.89e-02 | 9.60e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES | 43 | 8.79e-01 | -1.35e-02 | 9.60e-01 |
| REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES | 37 | 8.79e-01 | -1.44e-02 | 9.60e-01 |
| REACTOME RHO GTPASES ACTIVATE ROCKS | 19 | 8.80e-01 | -2.01e-02 | 9.60e-01 |
| REACTOME RORA ACTIVATES GENE EXPRESSION | 17 | 8.81e-01 | 2.10e-02 | 9.60e-01 |
| REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | 32 | 8.82e-01 | 1.51e-02 | 9.60e-01 |
| REACTOME RELAXIN RECEPTORS | 8 | 8.83e-01 | -3.01e-02 | 9.60e-01 |
| REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | 14 | 8.83e-01 | 2.28e-02 | 9.60e-01 |
| REACTOME SEROTONIN NEUROTRANSMITTER RELEASE CYCLE | 17 | 8.84e-01 | -2.05e-02 | 9.60e-01 |
| REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | 15 | 8.84e-01 | 2.17e-02 | 9.60e-01 |
| REACTOME PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS | 8 | 8.85e-01 | 2.94e-02 | 9.60e-01 |
| REACTOME GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION | 42 | 8.85e-01 | 1.29e-02 | 9.60e-01 |
| REACTOME RUNX3 REGULATES NOTCH SIGNALING | 13 | 8.86e-01 | 2.31e-02 | 9.60e-01 |
| REACTOME NFE2L2 REGULATING ANTI OXIDANT DETOXIFICATION ENZYMES | 17 | 8.86e-01 | -2.01e-02 | 9.60e-01 |
| REACTOME BETA DEFENSINS | 27 | 8.87e-01 | 1.58e-02 | 9.60e-01 |
| REACTOME TYPE I HEMIDESMOSOME ASSEMBLY | 11 | 8.87e-01 | 2.48e-02 | 9.60e-01 |
| REACTOME SIGNALING BY ACTIVIN | 15 | 8.88e-01 | -2.09e-02 | 9.61e-01 |
| REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ | 6 | 8.89e-01 | -3.30e-02 | 9.61e-01 |
| REACTOME CHAPERONE MEDIATED AUTOPHAGY | 20 | 8.89e-01 | -1.80e-02 | 9.61e-01 |
| REACTOME RHOD GTPASE CYCLE | 49 | 8.90e-01 | -1.14e-02 | 9.61e-01 |
| REACTOME INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | 28 | 8.93e-01 | 1.47e-02 | 9.63e-01 |
| REACTOME RELEASE OF HH NP FROM THE SECRETING CELL | 8 | 8.93e-01 | 2.74e-02 | 9.63e-01 |
| REACTOME DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS | 15 | 8.96e-01 | 1.95e-02 | 9.65e-01 |
| REACTOME GLYCOSPHINGOLIPID METABOLISM | 39 | 8.97e-01 | 1.20e-02 | 9.66e-01 |
| REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | 14 | 9.01e-01 | 1.91e-02 | 9.69e-01 |
| REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION | 42 | 9.02e-01 | 1.10e-02 | 9.69e-01 |
| REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | 27 | 9.03e-01 | 1.36e-02 | 9.69e-01 |
| REACTOME OAS ANTIVIRAL RESPONSE | 8 | 9.03e-01 | -2.49e-02 | 9.69e-01 |
| REACTOME MELANIN BIOSYNTHESIS | 5 | 9.04e-01 | 3.13e-02 | 9.69e-01 |
| REACTOME RHOBTB3 ATPASE CYCLE | 8 | 9.04e-01 | -2.46e-02 | 9.69e-01 |
| REACTOME ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS | 87 | 9.05e-01 | -7.42e-03 | 9.69e-01 |
| REACTOME P75NTR SIGNALS VIA NF KB | 15 | 9.05e-01 | 1.78e-02 | 9.69e-01 |
| REACTOME RETINOID CYCLE DISEASE EVENTS | 11 | 9.06e-01 | -2.05e-02 | 9.69e-01 |
| REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | 11 | 9.07e-01 | -2.03e-02 | 9.69e-01 |
| REACTOME TRIGLYCERIDE BIOSYNTHESIS | 12 | 9.07e-01 | 1.94e-02 | 9.69e-01 |
| REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | 13 | 9.08e-01 | 1.86e-02 | 9.69e-01 |
| REACTOME COHESIN LOADING ONTO CHROMATIN | 8 | 9.08e-01 | 2.36e-02 | 9.69e-01 |
| REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP | 41 | 9.09e-01 | 1.03e-02 | 9.70e-01 |
| REACTOME DEGRADATION OF CYSTEINE AND HOMOCYSTEINE | 15 | 9.09e-01 | 1.70e-02 | 9.70e-01 |
| REACTOME CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER | 25 | 9.10e-01 | 1.31e-02 | 9.70e-01 |
| REACTOME CONJUGATION OF BENZOATE WITH GLYCINE | 6 | 9.15e-01 | 2.53e-02 | 9.73e-01 |
| REACTOME COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM | 21 | 9.15e-01 | -1.34e-02 | 9.73e-01 |
| REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE | 11 | 9.16e-01 | 1.84e-02 | 9.73e-01 |
| REACTOME CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND | 9 | 9.16e-01 | -2.04e-02 | 9.73e-01 |
| REACTOME METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS | 122 | 9.17e-01 | -5.48e-03 | 9.73e-01 |
| REACTOME LINOLEIC ACID LA METABOLISM | 7 | 9.17e-01 | 2.28e-02 | 9.73e-01 |
| REACTOME P75NTR REGULATES AXONOGENESIS | 9 | 9.19e-01 | -1.96e-02 | 9.75e-01 |
| REACTOME ACYL CHAIN REMODELING OF CL | 5 | 9.19e-01 | 2.61e-02 | 9.75e-01 |
| REACTOME SYNTHESIS OF PC | 27 | 9.22e-01 | 1.09e-02 | 9.76e-01 |
| REACTOME RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY | 14 | 9.22e-01 | -1.51e-02 | 9.76e-01 |
| REACTOME TRANSPORT OF NUCLEOTIDE SUGARS | 8 | 9.24e-01 | -1.96e-02 | 9.77e-01 |
| REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | 30 | 9.24e-01 | -1.00e-02 | 9.77e-01 |
| REACTOME CELLULAR HEXOSE TRANSPORT | 21 | 9.25e-01 | 1.18e-02 | 9.77e-01 |
| REACTOME HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS | 7 | 9.26e-01 | 2.04e-02 | 9.77e-01 |
| REACTOME FREE FATTY ACID RECEPTORS | 5 | 9.26e-01 | 2.40e-02 | 9.77e-01 |
| REACTOME VIRAL MESSENGER RNA SYNTHESIS | 44 | 9.26e-01 | 8.07e-03 | 9.77e-01 |
| REACTOME CYTOSOLIC TRNA AMINOACYLATION | 22 | 9.28e-01 | -1.11e-02 | 9.78e-01 |
| REACTOME INTERLEUKIN 20 FAMILY SIGNALING | 25 | 9.30e-01 | -1.01e-02 | 9.79e-01 |
| REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION | 6 | 9.31e-01 | 2.06e-02 | 9.79e-01 |
| REACTOME INSULIN PROCESSING | 24 | 9.31e-01 | 1.02e-02 | 9.80e-01 |
| REACTOME MATURATION OF PROTEIN 3A | 9 | 9.33e-01 | -1.62e-02 | 9.80e-01 |
| REACTOME CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN | 45 | 9.33e-01 | 7.20e-03 | 9.80e-01 |
| REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | 15 | 9.33e-01 | -1.25e-02 | 9.80e-01 |
| REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | 24 | 9.34e-01 | -9.71e-03 | 9.80e-01 |
| REACTOME ERBB2 ACTIVATES PTK6 SIGNALING | 13 | 9.36e-01 | -1.28e-02 | 9.81e-01 |
| REACTOME BINDING OF TCF LEF CTNNB1 TO TARGET GENE PROMOTERS | 8 | 9.37e-01 | 1.60e-02 | 9.81e-01 |
| REACTOME TRAF6 MEDIATED NF KB ACTIVATION | 24 | 9.38e-01 | -9.20e-03 | 9.81e-01 |
| REACTOME DECTIN 2 FAMILY | 26 | 9.38e-01 | -8.79e-03 | 9.81e-01 |
| REACTOME APOPTOTIC FACTOR MEDIATED RESPONSE | 19 | 9.38e-01 | 1.02e-02 | 9.81e-01 |
| REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS | 101 | 9.39e-01 | 4.43e-03 | 9.81e-01 |
| REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | 16 | 9.39e-01 | 1.10e-02 | 9.81e-01 |
| REACTOME LYSINE CATABOLISM | 12 | 9.40e-01 | -1.26e-02 | 9.81e-01 |
| REACTOME SIGNALING BY NTRK3 TRKC | 17 | 9.41e-01 | -1.03e-02 | 9.81e-01 |
| REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | 23 | 9.43e-01 | 8.65e-03 | 9.81e-01 |
| REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION | 10 | 9.43e-01 | -1.31e-02 | 9.81e-01 |
| REACTOME ATTACHMENT OF GPI ANCHOR TO UPAR | 7 | 9.43e-01 | -1.56e-02 | 9.81e-01 |
| REACTOME SARS COV 2 TARGETS PDZ PROTEINS IN CELL CELL JUNCTION | 5 | 9.44e-01 | -1.82e-02 | 9.81e-01 |
| REACTOME SIGNALING BY NOTCH1 | 69 | 9.44e-01 | -4.90e-03 | 9.81e-01 |
| REACTOME FRUCTOSE METABOLISM | 7 | 9.45e-01 | 1.50e-02 | 9.82e-01 |
| REACTOME ATTENUATION PHASE | 27 | 9.47e-01 | -7.40e-03 | 9.83e-01 |
| REACTOME NEUROFASCIN INTERACTIONS | 6 | 9.48e-01 | 1.53e-02 | 9.83e-01 |
| REACTOME BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA | 6 | 9.49e-01 | -1.51e-02 | 9.83e-01 |
| REACTOME KINESINS | 59 | 9.51e-01 | -4.61e-03 | 9.83e-01 |
| REACTOME GLUTATHIONE CONJUGATION | 33 | 9.52e-01 | 6.00e-03 | 9.83e-01 |
| REACTOME RAS SIGNALING DOWNSTREAM OF NF1 LOSS OF FUNCTION VARIANTS | 7 | 9.53e-01 | 1.30e-02 | 9.83e-01 |
| REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS | 5 | 9.53e-01 | 1.53e-02 | 9.83e-01 |
| REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS | 63 | 9.53e-01 | -4.31e-03 | 9.83e-01 |
| REACTOME MYOGENESIS | 29 | 9.53e-01 | 6.34e-03 | 9.83e-01 |
| REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION | 11 | 9.53e-01 | 1.03e-02 | 9.83e-01 |
| REACTOME DNA REPLICATION INITIATION | 7 | 9.53e-01 | 1.29e-02 | 9.83e-01 |
| REACTOME FATTY ACID METABOLISM | 170 | 9.54e-01 | 2.54e-03 | 9.83e-01 |
| REACTOME NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 24 | 9.55e-01 | 6.72e-03 | 9.83e-01 |
| REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | 35 | 9.55e-01 | 5.54e-03 | 9.83e-01 |
| REACTOME AGGREPHAGY | 42 | 9.55e-01 | 5.03e-03 | 9.83e-01 |
| REACTOME HUR ELAVL1 BINDS AND STABILIZES MRNA | 8 | 9.56e-01 | -1.14e-02 | 9.83e-01 |
| REACTOME TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY | 16 | 9.57e-01 | 7.83e-03 | 9.84e-01 |
| REACTOME PLATELET CALCIUM HOMEOSTASIS | 27 | 9.58e-01 | -5.92e-03 | 9.84e-01 |
| REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE | 71 | 9.61e-01 | 3.39e-03 | 9.85e-01 |
| REACTOME DEFECTS IN VITAMIN AND COFACTOR METABOLISM | 21 | 9.61e-01 | -6.13e-03 | 9.85e-01 |
| REACTOME IRS ACTIVATION | 5 | 9.62e-01 | -1.24e-02 | 9.85e-01 |
| REACTOME NEF MEDIATED CD8 DOWN REGULATION | 7 | 9.62e-01 | 1.04e-02 | 9.85e-01 |
| REACTOME ACTIVATION OF AMPK DOWNSTREAM OF NMDARS | 28 | 9.63e-01 | -5.05e-03 | 9.85e-01 |
| REACTOME SIGNALING BY FGFR4 IN DISEASE | 11 | 9.63e-01 | 8.03e-03 | 9.85e-01 |
| REACTOME SPERM MOTILITY AND TAXES | 9 | 9.65e-01 | -8.44e-03 | 9.85e-01 |
| REACTOME FREE FATTY ACIDS REGULATE INSULIN SECRETION | 10 | 9.65e-01 | 7.99e-03 | 9.85e-01 |
| REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS | 19 | 9.66e-01 | -5.61e-03 | 9.85e-01 |
| REACTOME MICRORNA MIRNA BIOGENESIS | 25 | 9.66e-01 | 4.89e-03 | 9.85e-01 |
| REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III | 31 | 9.67e-01 | -4.35e-03 | 9.85e-01 |
| REACTOME INLA MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS | 9 | 9.67e-01 | -7.91e-03 | 9.85e-01 |
| REACTOME ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING | 23 | 9.68e-01 | -4.88e-03 | 9.85e-01 |
| REACTOME VITAMIN B1 THIAMIN METABOLISM | 5 | 9.68e-01 | -1.04e-02 | 9.85e-01 |
| REACTOME ROBO RECEPTORS BIND AKAP5 | 9 | 9.69e-01 | -7.57e-03 | 9.85e-01 |
| REACTOME JOSEPHIN DOMAIN DUBS | 11 | 9.69e-01 | -6.82e-03 | 9.85e-01 |
| REACTOME RECYCLING PATHWAY OF L1 | 43 | 9.69e-01 | -3.45e-03 | 9.85e-01 |
| REACTOME NEF MEDIATED CD4 DOWN REGULATION | 9 | 9.70e-01 | 7.22e-03 | 9.86e-01 |
| REACTOME METALLOTHIONEINS BIND METALS | 11 | 9.72e-01 | 6.21e-03 | 9.87e-01 |
| REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | 21 | 9.74e-01 | -4.14e-03 | 9.88e-01 |
| REACTOME SCAVENGING OF HEME FROM PLASMA | 13 | 9.78e-01 | 4.46e-03 | 9.91e-01 |
| REACTOME METHIONINE SALVAGE PATHWAY | 6 | 9.78e-01 | -6.48e-03 | 9.91e-01 |
| REACTOME FORMATION OF AXIAL MESODERM | 14 | 9.78e-01 | -4.20e-03 | 9.91e-01 |
| REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS | 6 | 9.81e-01 | 5.71e-03 | 9.93e-01 |
| REACTOME FATTY ACIDS BOUND TO GPR40 FFAR1 REGULATE INSULIN SECRETION | 8 | 9.81e-01 | 4.83e-03 | 9.93e-01 |
| REACTOME PREGNENOLONE BIOSYNTHESIS | 12 | 9.83e-01 | 3.63e-03 | 9.94e-01 |
| REACTOME IRF3 MEDIATED INDUCTION OF TYPE I IFN | 13 | 9.86e-01 | -2.87e-03 | 9.96e-01 |
| REACTOME SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX | 15 | 9.86e-01 | 2.64e-03 | 9.96e-01 |
| REACTOME ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS | 20 | 9.89e-01 | -1.71e-03 | 9.98e-01 |
| REACTOME FORMATION OF LATERAL PLATE MESODERM | 5 | 9.90e-01 | 3.38e-03 | 9.98e-01 |
| REACTOME SMOOTH MUSCLE CONTRACTION | 43 | 9.90e-01 | 1.05e-03 | 9.98e-01 |
| REACTOME GERM LAYER FORMATION AT GASTRULATION | 17 | 9.91e-01 | 1.59e-03 | 9.98e-01 |
| REACTOME DEFECTIVE RIPK1 MEDIATED REGULATED NECROSIS | 7 | 9.92e-01 | -2.12e-03 | 9.98e-01 |
| REACTOME EPHB MEDIATED FORWARD SIGNALING | 41 | 9.93e-01 | 7.51e-04 | 9.98e-01 |
| REACTOME SYNDECAN INTERACTIONS | 26 | 9.93e-01 | -9.38e-04 | 9.98e-01 |
| REACTOME FGFR1C LIGAND BINDING AND ACTIVATION | 11 | 9.94e-01 | -1.28e-03 | 9.98e-01 |
| REACTOME RHO GTPASES ACTIVATE CIT | 19 | 9.94e-01 | -9.72e-04 | 9.98e-01 |
| REACTOME SODIUM COUPLED PHOSPHATE COTRANSPORTERS | 5 | 9.96e-01 | -1.40e-03 | 9.99e-01 |
| REACTOME PI3K AKT ACTIVATION | 9 | 9.97e-01 | 7.68e-04 | 1.00e+00 |
| REACTOME RHO GTPASES ACTIVATE KTN1 | 11 | 9.98e-01 | -4.88e-04 | 1.00e+00 |
| REACTOME RHO GTPASE CYCLE | 423 | 9.98e-01 | -6.19e-05 | 1.00e+00 |
| REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | 17 | 9.98e-01 | -2.73e-04 | 1.00e+00 |
| REACTOME PROCESSING OF SMDT1 | 16 | 9.99e-01 | 1.82e-04 | 1.00e+00 |
| REACTOME GPER1 SIGNALING | 45 | 1.00e+00 | -4.05e-06 | 1.00e+00 |
Detailed Gene set reports
REACTOME_METABOLISM_OF_RNA
| 1313 | |
|---|---|
| set | REACTOME_METABOLISM_OF_RNA |
| setSize | 675 |
| pANOVA | 5.27e-17 |
| s.dist | 0.189 |
| p.adjustANOVA | 8.65e-14 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| THOC3 | 10946 |
| APOBEC3B | 10937 |
| APOBEC3A | 10910 |
| APOBEC3C | 10714 |
| SRSF6 | 10598 |
| TNFSF13 | 10569 |
| ZNF473 | 10420 |
| POLR2K | 10402 |
| LSM8 | 10352 |
| PSMD12 | 10325 |
| CNOT8 | 10218 |
| RPL14 | 10215 |
| LENG1 | 10140 |
| THOC6 | 10125 |
| ACIN1 | 10116 |
| ZFP36 | 10115 |
| POP7 | 10088 |
| RPL18 | 10082 |
| FUS | 10080 |
| SDE2 | 10050 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| THOC3 | 10946.0 |
| APOBEC3B | 10937.0 |
| APOBEC3A | 10910.0 |
| APOBEC3C | 10714.0 |
| SRSF6 | 10598.0 |
| TNFSF13 | 10569.0 |
| ZNF473 | 10420.0 |
| POLR2K | 10402.0 |
| LSM8 | 10352.0 |
| PSMD12 | 10325.0 |
| CNOT8 | 10218.0 |
| RPL14 | 10215.0 |
| LENG1 | 10140.0 |
| THOC6 | 10125.0 |
| ACIN1 | 10116.0 |
| ZFP36 | 10115.0 |
| POP7 | 10088.0 |
| RPL18 | 10082.0 |
| FUS | 10080.0 |
| SDE2 | 10050.0 |
| SNRNP25 | 10044.0 |
| LSM1 | 10042.0 |
| RPL10A | 10035.0 |
| SNRPB2 | 10026.0 |
| EIF4A1 | 10017.0 |
| PSMC6 | 9977.0 |
| WBP11 | 9955.0 |
| TP53RK | 9916.0 |
| ISG20L2 | 9875.0 |
| EXOSC5 | 9863.0 |
| PSMB3 | 9858.0 |
| RPL23A | 9830.0 |
| CSTF2T | 9749.0 |
| RPS13 | 9737.0 |
| GTPBP3 | 9720.0 |
| UTP4 | 9709.0 |
| DIMT1 | 9686.0 |
| TRMT12 | 9597.0 |
| RBM8A | 9578.0 |
| ZBTB8OS | 9565.0 |
| PRKRIP1 | 9540.0 |
| CCDC12 | 9515.0 |
| UBC | 9476.0 |
| RPL38 | 9474.0 |
| XPOT | 9472.0 |
| HSPB1 | 9467.0 |
| EXOSC1 | 9393.0 |
| HNRNPR | 9325.0 |
| RPS21 | 9255.0 |
| IMP3 | 9232.0 |
| TRMT61B | 9229.0 |
| RPLP0 | 9213.0 |
| PCBP1 | 9188.0 |
| RPL29 | 9165.0 |
| CWC22 | 9154.0 |
| IMP4 | 9147.0 |
| DDX20 | 9118.0 |
| CNOT11 | 9045.0 |
| RPP40 | 9016.0 |
| RPP25 | 8979.0 |
| HNRNPA1 | 8950.0 |
| RPS3A | 8946.0 |
| POM121 | 8943.0 |
| BUD13 | 8917.0 |
| SNU13 | 8897.0 |
| RPL28 | 8875.0 |
| CPSF6 | 8868.0 |
| DHX35 | 8846.0 |
| UTP6 | 8835.0 |
| PRCC | 8826.0 |
| DHX8 | 8808.0 |
| KHSRP | 8781.0 |
| MAPK14 | 8739.0 |
| SAP18 | 8722.0 |
| ZFP36L1 | 8715.0 |
| PSME2 | 8685.0 |
| TRMT10C | 8680.0 |
| HNRNPA3 | 8653.0 |
| METTL14 | 8628.0 |
| TRA2B | 8610.0 |
| SMNDC1 | 8551.0 |
| PABPC1 | 8543.0 |
| RBM7 | 8508.0 |
| SRSF1 | 8481.0 |
| DDX39B | 8477.0 |
| RPL36AL | 8459.5 |
| RPL22L1 | 8449.0 |
| CCNH | 8435.0 |
| APOBEC4 | 8408.0 |
| SF1 | 8324.0 |
| RPL31 | 8273.0 |
| PSMB4 | 8180.0 |
| RPS24 | 8170.0 |
| SNRNP35 | 8137.0 |
| RPS23 | 8094.0 |
| RPPH1 | 8084.0 |
| ALYREF | 8040.0 |
| SF3A3 | 8036.0 |
| RPL26 | 8016.0 |
| DDX21 | 7989.0 |
| EXOSC9 | 7985.0 |
| CNOT6 | 7981.0 |
| GPATCH1 | 7963.0 |
| NOL11 | 7955.0 |
| ZC3H11A | 7947.0 |
| POLR2I | 7943.0 |
| WBP4 | 7909.0 |
| RPS20 | 7907.0 |
| LSM11 | 7904.0 |
| PSMD13 | 7901.0 |
| TRMT1 | 7871.0 |
| NT5C3B | 7845.0 |
| LSM3 | 7788.0 |
| NUP155 | 7761.0 |
| UPF2 | 7759.0 |
| XAB2 | 7738.0 |
| SNW1 | 7713.0 |
| PSME4 | 7705.0 |
| ZMAT2 | 7687.0 |
| CPSF2 | 7686.0 |
| UBB | 7674.0 |
| PSMB2 | 7641.0 |
| RPS29 | 7621.0 |
| GEMIN6 | 7578.0 |
| EIF4E | 7566.0 |
| EPRS1 | 7532.0 |
| TSEN54 | 7525.0 |
| ERCC2 | 7510.0 |
| DIS3 | 7503.0 |
| HSPA8 | 7490.0 |
| SF3A2 | 7446.0 |
| RPL34 | 7423.0 |
| RPS19 | 7419.0 |
| ALKBH8 | 7415.0 |
| RPS3 | 7411.0 |
| GAR1 | 7394.0 |
| PSMB11 | 7359.0 |
| ZCRB1 | 7357.0 |
| RPL41 | 7335.0 |
| PPIL4 | 7317.0 |
| RPL6 | 7304.0 |
| DCAF13 | 7270.0 |
| PAIP1 | 7255.0 |
| WDR3 | 7237.0 |
| PWP2 | 7235.0 |
| PSMA6 | 7190.0 |
| PES1 | 7181.0 |
| LSM5 | 7137.0 |
| RPS27A | 7120.0 |
| GTF2H1 | 7100.0 |
| PPIH | 7024.0 |
| PSMA1 | 7018.0 |
| METTL1 | 6989.0 |
| HNRNPU | 6963.0 |
| RPL23 | 6935.0 |
| SENP3 | 6893.0 |
| EXOSC4 | 6868.0 |
| SEH1L | 6838.0 |
| NAT10 | 6830.0 |
| BMS1 | 6826.0 |
| NUP35 | 6822.0 |
| ANP32A | 6719.0 |
| RPP21 | 6718.0 |
| NUP85 | 6688.0 |
| PSMD3 | 6672.0 |
| SF3A1 | 6611.0 |
| LSM6 | 6601.0 |
| CDC40 | 6559.0 |
| RTRAF | 6546.0 |
| SF3B4 | 6527.0 |
| HNRNPM | 6478.0 |
| U2AF1L4 | 6453.0 |
| FAU | 6424.0 |
| EIF4A3 | 6420.0 |
| RPL11 | 6414.0 |
| C2orf49 | 6395.0 |
| SKIC2 | 6350.0 |
| RPL21 | 6341.0 |
| U2SURP | 6325.0 |
| PCF11 | 6318.0 |
| SNRNP27 | 6315.0 |
| NUP37 | 6306.0 |
| DUS2 | 6305.0 |
| NXT1 | 6293.0 |
| RBM25 | 6214.0 |
| NHP2 | 6142.0 |
| RPL13 | 6125.0 |
| SNRNP48 | 6085.0 |
| DDX5 | 6081.0 |
| RPS26 | 6058.0 |
| EDC3 | 6015.0 |
| SNUPN | 6013.0 |
| TRIT1 | 6001.0 |
| RPL7A | 5991.0 |
| GTF2H3 | 5990.0 |
| RPP14 | 5987.0 |
| PDCD7 | 5973.0 |
| TRMT44 | 5934.0 |
| TEX10 | 5932.0 |
| NUP43 | 5921.0 |
| RPS16 | 5896.0 |
| MPHOSPH10 | 5885.0 |
| YWHAB | 5879.0 |
| GEMIN4 | 5843.0 |
| RPL8 | 5822.0 |
| PPWD1 | 5778.0 |
| CDC5L | 5770.0 |
| CSTF3 | 5738.0 |
| FCF1 | 5733.0 |
| PRPF38A | 5727.0 |
| RPS7 | 5716.0 |
| PSMC1 | 5715.0 |
| RPP38 | 5714.0 |
| NCBP1 | 5705.0 |
| RAN | 5697.0 |
| NUP54 | 5644.0 |
| UBL5 | 5627.0 |
| PSMD2 | 5624.0 |
| TRMT112 | 5611.0 |
| RPL26L1 | 5531.0 |
| NOP2 | 5509.0 |
| PABPN1 | 5490.0 |
| TRMT13 | 5475.0 |
| SNRNP70 | 5447.0 |
| RPS8 | 5431.0 |
| CSTF1 | 5411.0 |
| PSMA5 | 5362.0 |
| SRSF3 | 5357.0 |
| WDR46 | 5343.0 |
| CTU1 | 5325.0 |
| RPL37A | 5292.0 |
| PSMA4 | 5246.0 |
| MRM3 | 5238.0 |
| LSM7 | 5224.0 |
| SNRPF | 5221.0 |
| RPL3L | 5206.0 |
| PSMC5 | 5193.0 |
| DDX47 | 5191.0 |
| SNRPD2 | 5177.0 |
| RPL13A | 5131.5 |
| SF3B3 | 5113.0 |
| CWC15 | 5108.0 |
| SRSF7 | 5105.0 |
| RBM5 | 5075.0 |
| NUP107 | 5069.0 |
| SMG5 | 5060.0 |
| RPS10 | 5058.0 |
| SMG7 | 5028.0 |
| IK | 4985.0 |
| SKIC8 | 4957.0 |
| POLDIP3 | 4943.0 |
| HNRNPC | 4936.0 |
| DCPS | 4931.0 |
| RPL19 | 4913.0 |
| RPS18 | 4856.0 |
| NUP88 | 4788.0 |
| RPL9 | 4760.0 |
| RPS27 | 4711.0 |
| NUP133 | 4676.0 |
| YWHAZ | 4655.0 |
| SMN1 | 4648.5 |
| SMN2 | 4648.5 |
| CNOT1 | 4620.0 |
| PRPF19 | 4618.0 |
| NSRP1 | 4543.0 |
| RNPS1 | 4528.0 |
| SF3B1 | 4515.0 |
| RPS12 | 4501.0 |
| DHX16 | 4492.0 |
| LSM2 | 4491.0 |
| PCBP2 | 4487.0 |
| RPL35 | 4434.0 |
| FAM32A | 4431.0 |
| SLU7 | 4319.0 |
| PSMF1 | 4311.0 |
| PPP1R8 | 4282.0 |
| UPF1 | 4279.0 |
| EXOSC3 | 4242.0 |
| PSMD1 | 4227.0 |
| RPL35A | 4218.0 |
| RPL17 | 4202.0 |
| PSME3 | 4172.0 |
| SARNP | 4167.0 |
| MAPKAPK2 | 4162.0 |
| EBNA1BP2 | 4140.0 |
| PSMC2 | 4088.0 |
| TNPO1 | 4083.0 |
| KRR1 | 4067.0 |
| CASC3 | 4044.0 |
| BOP1 | 3984.0 |
| PSMA8 | 3923.0 |
| POLR2A | 3916.0 |
| PSMA7 | 3903.0 |
| SNRNP40 | 3887.0 |
| PSME1 | 3866.0 |
| HNRNPA2B1 | 3853.0 |
| PSMA3 | 3850.0 |
| TRMT61A | 3819.0 |
| SRSF2 | 3788.0 |
| SMG1 | 3772.0 |
| NOL12 | 3746.0 |
| NUP205 | 3738.0 |
| DCP1B | 3669.0 |
| SYMPK | 3608.0 |
| UTP11 | 3571.0 |
| DDX39A | 3522.0 |
| XRN2 | 3496.0 |
| PSMB9 | 3459.0 |
| SNRPG | 3425.0 |
| TYW5 | 3407.0 |
| WDR36 | 3393.0 |
| RPSA | 3281.0 |
| RPL3 | 3240.0 |
| SF3B2 | 3227.0 |
| RBM42 | 3200.0 |
| EIF4A2 | 3184.0 |
| CSNK1D | 3179.0 |
| POLR2E | 3177.0 |
| DHX15 | 3157.0 |
| SET | 3096.0 |
| DDX1 | 3094.0 |
| ADAT3 | 3090.0 |
| FTSJ3 | 3085.0 |
| NOP10 | 3084.0 |
| PRMT5 | 3035.0 |
| EXOSC7 | 3025.0 |
| PSMC4 | 3004.0 |
| SNRPA | 3000.0 |
| USP39 | 2963.0 |
| PSMC3 | 2960.0 |
| GTF2F2 | 2945.0 |
| CPSF7 | 2925.0 |
| RBM28 | 2908.0 |
| PARN | 2863.0 |
| NUP42 | 2844.0 |
| ADAT1 | 2825.0 |
| RPL12 | 2822.0 |
| CHTOP | 2800.0 |
| ISY1 | 2794.0 |
| NUP93 | 2792.0 |
| NXF1 | 2722.0 |
| HNRNPD | 2711.0 |
| NUP58 | 2703.0 |
| NIP7 | 2677.0 |
| RPS28 | 2669.0 |
| NSUN4 | 2656.0 |
| RANBP2 | 2651.0 |
| BUD31 | 2642.0 |
| RRP9 | 2631.0 |
| SEM1 | 2517.0 |
| RPL27A | 2494.0 |
| RIOK3 | 2488.0 |
| ERCC3 | 2481.0 |
| MFAP1 | 2472.0 |
| NCL | 2444.0 |
| YBX1 | 2391.0 |
| TSEN2 | 2386.0 |
| RPL15 | 2382.0 |
| RPL32 | 2362.0 |
| TRMT10A | 2318.0 |
| PPP2CA | 2292.0 |
| SMU1 | 2278.0 |
| TRMT6 | 2268.0 |
| THOC7 | 2236.0 |
| LUC7L3 | 2199.0 |
| ADARB1 | 2145.0 |
| NUDT21 | 2107.0 |
| RPS15A | 2095.0 |
| PATL1 | 2088.0 |
| TGS1 | 2080.0 |
| TSEN34 | 2054.0 |
| POLR2D | 2025.0 |
| RNPC3 | 2017.0 |
| THG1L | 2016.0 |
| MTREX | 1999.0 |
| RPS25 | 1988.0 |
| EMG1 | 1863.0 |
| PAN2 | 1851.0 |
| IGF2BP1 | 1844.0 |
| IGF2BP3 | 1813.0 |
| UTP20 | 1796.0 |
| CPSF1 | 1778.0 |
| RPLP1 | 1762.0 |
| ADAT2 | 1712.0 |
| UTP18 | 1686.0 |
| SRSF4 | 1674.0 |
| SNRPD1 | 1669.0 |
| NOC4L | 1635.0 |
| MRM1 | 1605.0 |
| RNGTT | 1562.0 |
| EIF4G1 | 1551.0 |
| WDR18 | 1532.0 |
| BCAS2 | 1531.0 |
| PRPF3 | 1521.0 |
| RBM17 | 1505.0 |
| SRRT | 1488.0 |
| FBL | 1467.0 |
| APOBEC2 | 1445.0 |
| RPL7 | 1442.0 |
| GTF2H4 | 1369.0 |
| CNOT4 | 1341.0 |
| DDX52 | 1328.0 |
| CNOT9 | 1314.0 |
| SNRPD3 | 1285.0 |
| SF3B5 | 1282.0 |
| RRP1 | 1280.0 |
| WDR77 | 1252.0 |
| WDR70 | 1161.0 |
| PRORP | 1099.0 |
| PNRC2 | 1090.0 |
| SNRPE | 1082.0 |
| ADAR | 1076.0 |
| PPP2R2A | 1071.0 |
| SMG9 | 1036.0 |
| PRPF40A | 1016.0 |
| TUT4 | 970.0 |
| FYTTD1 | 934.0 |
| WDR33 | 931.0 |
| TFIP11 | 924.0 |
| NOP58 | 789.0 |
| POP1 | 767.0 |
| DDX23 | 718.0 |
| PRPF31 | 669.0 |
| PSMD11 | 620.0 |
| CWF19L2 | 612.0 |
| HNRNPK | 537.0 |
| DDX49 | 519.0 |
| DHX38 | 488.0 |
| QTRT2 | 455.0 |
| PSMB8 | 447.0 |
| CWC25 | 432.0 |
| RBM39 | 422.0 |
| PDCD11 | 314.0 |
| SRSF9 | 313.0 |
| GEMIN7 | 272.0 |
| TSR1 | 225.0 |
| GEMIN5 | 184.0 |
| PRPF18 | 75.0 |
| GCFC2 | 71.0 |
| CACTIN | 69.0 |
| TRMU | 44.0 |
| TUT7 | -7.0 |
| TYW1 | -72.0 |
| LSM10 | -75.0 |
| U2AF2 | -78.0 |
| PSMA2 | -85.0 |
| PRPF4 | -97.0 |
| PUS3 | -116.0 |
| EXOSC8 | -119.0 |
| SRSF10 | -125.0 |
| RPL5 | -139.0 |
| PELP1 | -199.0 |
| TRMT5 | -234.0 |
| SNRPA1 | -241.0 |
| PRPF8 | -262.0 |
| HNRNPL | -321.0 |
| NUP98 | -351.0 |
| FAM98B | -398.0 |
| URM1 | -409.0 |
| RRP36 | -455.0 |
| WDR43 | -495.0 |
| PHAX | -508.0 |
| TFB1M | -523.0 |
| SKIC3 | -535.0 |
| MTERF4 | -537.0 |
| CNOT7 | -539.0 |
| PUS7 | -549.0 |
| WDR4 | -551.0 |
| C1D | -558.0 |
| POP4 | -559.0 |
| EXOSC10 | -564.0 |
| DDX42 | -575.0 |
| SMG8 | -579.0 |
| SNRNP200 | -715.0 |
| MNAT1 | -717.0 |
| AQR | -718.0 |
| PLRG1 | -765.0 |
| GNL3 | -792.0 |
| CLP1 | -801.0 |
| PSMD14 | -865.0 |
| NSUN6 | -881.0 |
| UTP3 | -923.0 |
| THOC1 | -929.0 |
| LTV1 | -957.0 |
| PSMD6 | -961.0 |
| THUMPD1 | -968.0 |
| POLR2L | -971.0 |
| SRSF5 | -979.0 |
| PPIL3 | -1003.0 |
| MTO1 | -1005.0 |
| RPS2 | -1028.0 |
| XPO1 | -1083.0 |
| DDX46 | -1107.0 |
| SNRPB | -1171.0 |
| TSEN15 | -1202.0 |
| PSMB7 | -1294.0 |
| PNO1 | -1296.0 |
| NDC1 | -1433.0 |
| ZNF830 | -1443.0 |
| EXOSC6 | -1460.0 |
| PTBP1 | -1545.0 |
| TRDMT1 | -1609.0 |
| RPS14 | -1691.0 |
| WDR75 | -1740.0 |
| HNRNPF | -1749.0 |
| TRNT1 | -1760.0 |
| MAGOHB | -1800.0 |
| CNOT2 | -1828.0 |
| TBL3 | -1859.0 |
| NUP188 | -1877.0 |
| RPL30 | -2061.0 |
| PPP2R1A | -2107.0 |
| HNRNPH1 | -2127.0 |
| HBS1L | -2138.0 |
| MAPK11 | -2236.0 |
| CHERP | -2247.0 |
| THOC5 | -2259.0 |
| PSMB10 | -2290.0 |
| NOL6 | -2304.0 |
| GTF2H5 | -2337.0 |
| PSMB6 | -2408.0 |
| GSPT1 | -2497.0 |
| DDX6 | -2505.0 |
| CNOT3 | -2521.0 |
| AKT1 | -2548.0 |
| PSMD9 | -2570.0 |
| ETF1 | -2575.0 |
| RPS5 | -2579.0 |
| OSGEP | -2588.0 |
| RPS6 | -2673.0 |
| POP5 | -2691.0 |
| CPSF3 | -2788.0 |
| RCL1 | -2819.0 |
| AAAS | -2839.0 |
| SRRM2 | -2879.0 |
| MRM2 | -2922.0 |
| PAN3 | -3013.0 |
| TRMT9B | -3089.0 |
| RPL39L | -3132.0 |
| NCBP2 | -3139.0 |
| PRKCA | -3175.0 |
| DHX37 | -3197.0 |
| NOB1 | -3201.0 |
| POLR2B | -3234.0 |
| PNN | -3265.0 |
| RPL37 | -3282.0 |
| RRP7A | -3304.0 |
| SYF2 | -3308.0 |
| DCP2 | -3374.0 |
| PPIL2 | -3402.0 |
| NUP153 | -3416.0 |
| THADA | -3500.0 |
| RAE1 | -3503.0 |
| EIF4B | -3542.0 |
| PRPF6 | -3660.0 |
| WDR12 | -3727.0 |
| UBA52 | -3755.0 |
| PUF60 | -3784.0 |
| CPSF4 | -3838.0 |
| POM121C | -4045.0 |
| CLNS1A | -4085.0 |
| SMG6 | -4132.0 |
| RPS15 | -4150.0 |
| CCAR1 | -4182.0 |
| SRSF11 | -4246.0 |
| HEATR1 | -4265.0 |
| SUPT5H | -4276.0 |
| MPHOSPH6 | -4287.0 |
| SNIP1 | -4467.0 |
| CNOT6L | -4491.0 |
| SART1 | -4493.0 |
| GTF2F1 | -4505.0 |
| TYW3 | -4525.0 |
| UTP25 | -4611.0 |
| CTU2 | -4624.0 |
| RPL24 | -4644.0 |
| RIOK2 | -4648.0 |
| RPS9 | -4650.0 |
| NSUN2 | -4661.0 |
| CNOT10 | -4682.0 |
| PSMB5 | -4687.0 |
| PHF5A | -4716.0 |
| LCMT2 | -4733.0 |
| POLR2F | -4762.0 |
| TRMT11 | -4850.0 |
| CDK7 | -4917.0 |
| YJU2 | -5034.0 |
| IGF2BP2 | -5086.0 |
| ELAVL1 | -5092.0 |
| EFTUD2 | -5125.0 |
| RPL4 | -5128.0 |
| PSMD7 | -5198.0 |
| A1CF | -5241.0 |
| RPL27 | -5306.0 |
| PSMD4 | -5337.0 |
| NOP56 | -5343.0 |
| PRKCD | -5412.0 |
| RPL18A | -5425.0 |
| POLR2C | -5430.0 |
| NUP214 | -5472.0 |
| RIOK1 | -5473.0 |
| RNMT | -5497.0 |
| PPIL1 | -5576.0 |
| TXNL4A | -5645.0 |
| SEC13 | -5670.0 |
| UTP15 | -5740.0 |
| RPL22 | -5765.0 |
| RPLP2 | -5777.0 |
| RPP30 | -5830.0 |
| PSMB1 | -5858.0 |
| BUD23 | -5862.0 |
| SRRM1 | -5879.0 |
| QTRT1 | -5904.0 |
| EDC4 | -5912.0 |
| PAPOLA | -5925.0 |
| RPS27L | -5945.0 |
| POLR2J | -6011.0 |
| CDKAL1 | -6024.0 |
| CWC27 | -6061.0 |
| PPIG | -6168.0 |
| DDX41 | -6179.0 |
| NUP50 | -6183.0 |
| POLR2H | -6261.0 |
| BYSL | -6382.0 |
| METTL3 | -6395.0 |
| RTCB | -6442.0 |
| HSPA1A | -6507.0 |
| PPIE | -6522.0 |
| SRSF8 | -6558.0 |
| LSM4 | -6630.0 |
| NUP210 | -6637.0 |
| EXOSC2 | -6711.0 |
| TNKS1BP1 | -6850.0 |
| SNRPN | -6912.0 |
| TSR3 | -6934.0 |
| DNAJC8 | -7033.0 |
| GLE1 | -7045.0 |
| DCP1A | -7071.0 |
| C9orf78 | -7122.0 |
| NUP160 | -7169.0 |
| NUP62 | -7266.0 |
| SNRPC | -7354.0 |
| CSNK1E | -7527.0 |
| APOBEC3H | -7601.0 |
| CRNKL1 | -7626.0 |
| PSMD8 | -7723.0 |
| CTNNBL1 | -7759.0 |
| PUS1 | -7764.0 |
| UPF3A | -7770.0 |
| SUGP1 | -7917.0 |
| ZMAT5 | -7941.0 |
| FIP1L1 | -8037.0 |
| WTAP | -8133.0 |
| RPL36 | -8155.0 |
| NOP14 | -8179.0 |
| TCERG1 | -8276.0 |
| POLR2G | -8279.0 |
| SRSF12 | -8418.0 |
| RPS11 | -8626.0 |
| NOL9 | -8684.0 |
| UTP14C | -8778.0 |
| DHX9 | -8784.0 |
| RBM22 | -8902.0 |
| XRN1 | -9024.0 |
| SF3B6 | -9034.0 |
| TPR | -9043.0 |
| APOBEC1 | -9080.0 |
| SLBP | -9081.0 |
| TPRKB | -9174.0 |
| MAGOH | -9309.0 |
| PSMD5 | -9524.0 |
| ERI1 | -9535.0 |
| RPL10L | -10090.0 |
| ELAC2 | -10097.0 |
| GEMIN2 | -10316.0 |
REACTOME_CELLULAR_RESPONSES_TO_STIMULI
| 1314 | |
|---|---|
| set | REACTOME_CELLULAR_RESPONSES_TO_STIMULI |
| setSize | 779 |
| pANOVA | 4.39e-14 |
| s.dist | 0.159 |
| p.adjustANOVA | 3.61e-11 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| HBA2 | 11087 |
| DDX11 | 10995 |
| ELOB | 10991 |
| H1-0 | 10953 |
| HSPA13 | 10807 |
| E2F1 | 10764 |
| CDKN2D | 10762 |
| H4C8 | 10752 |
| CDK4 | 10506 |
| GPX7 | 10381 |
| PSMD12 | 10325 |
| CDKN2B | 10314 |
| BLVRA | 10227 |
| DYNC1LI2 | 10216 |
| RPL14 | 10215 |
| AGO1 | 10212 |
| BAG5 | 10209 |
| EPO | 10172 |
| XBP1 | 10155 |
| SUZ12 | 10134 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| HBA2 | 11087.0 |
| DDX11 | 10995.0 |
| ELOB | 10991.0 |
| H1-0 | 10953.0 |
| HSPA13 | 10807.0 |
| E2F1 | 10764.0 |
| CDKN2D | 10762.0 |
| H4C8 | 10752.0 |
| CDK4 | 10506.0 |
| GPX7 | 10381.0 |
| PSMD12 | 10325.0 |
| CDKN2B | 10314.0 |
| BLVRA | 10227.0 |
| DYNC1LI2 | 10216.0 |
| RPL14 | 10215.0 |
| AGO1 | 10212.0 |
| BAG5 | 10209.0 |
| EPO | 10172.0 |
| XBP1 | 10155.0 |
| SUZ12 | 10134.0 |
| KLHDC3 | 10121.0 |
| CREB3L3 | 10092.0 |
| RPL18 | 10082.0 |
| ATP6V1G2 | 10077.0 |
| TRIM21 | 10071.0 |
| ID1 | 10059.0 |
| RPL10A | 10035.0 |
| COX11 | 10031.0 |
| HBA1 | 9991.0 |
| PSMC6 | 9977.0 |
| SNCB | 9969.0 |
| WIPI1 | 9913.0 |
| ATP6V0E1 | 9908.0 |
| ERN1 | 9896.0 |
| H2AJ | 9870.0 |
| EXOSC5 | 9863.0 |
| PSMB3 | 9858.0 |
| EIF2AK3 | 9850.0 |
| RPL23A | 9830.0 |
| MEF2D | 9823.0 |
| SYVN1 | 9799.0 |
| TLR4 | 9756.0 |
| RPS13 | 9737.0 |
| MED1 | 9736.0 |
| H1-3 | 9718.0 |
| CYCS | 9670.0 |
| MT1H | 9667.0 |
| MRPL18 | 9632.0 |
| JUN | 9609.0 |
| CXCL8 | 9558.0 |
| PREB | 9523.0 |
| ATP6V0E2 | 9509.0 |
| ATF4 | 9477.0 |
| UBC | 9476.0 |
| RPL38 | 9474.0 |
| STAT3 | 9471.0 |
| HSPB1 | 9467.0 |
| MIR24-2 | 9434.0 |
| DCTN4 | 9420.0 |
| ELOC | 9413.0 |
| EXOSC1 | 9393.0 |
| BAG4 | 9301.0 |
| RBX1 | 9293.0 |
| LY96 | 9278.0 |
| LAMTOR4 | 9268.0 |
| RPS21 | 9255.0 |
| KAT5 | 9221.0 |
| IL6 | 9220.0 |
| RPLP0 | 9213.0 |
| LRPPRC | 9205.0 |
| RPL29 | 9165.0 |
| SESN2 | 9164.0 |
| GPX8 | 9139.0 |
| GPX3 | 9136.0 |
| ERF | 9089.0 |
| TUBB6 | 9058.0 |
| PPP2R5B | 9055.0 |
| H3C10 | 9015.0 |
| TXN | 8969.0 |
| H3C11 | 8963.0 |
| DNAJC7 | 8949.0 |
| RPS3A | 8946.0 |
| POM121 | 8943.0 |
| MT1G | 8936.0 |
| H4C12 | 8883.0 |
| RPL28 | 8875.0 |
| KHSRP | 8781.0 |
| ATP6V0D2 | 8747.0 |
| MAPK14 | 8739.0 |
| CSNK2B | 8721.0 |
| NCF2 | 8692.0 |
| H4C2 | 8690.0 |
| PSME2 | 8685.0 |
| ATP6V1F | 8669.0 |
| BAG1 | 8660.0 |
| SHC1 | 8640.0 |
| H3-3A | 8639.0 |
| ATP6V1G1 | 8624.0 |
| H2BC13 | 8609.0 |
| ATP6V1C1 | 8602.0 |
| LAMTOR2 | 8526.0 |
| COX4I1 | 8524.0 |
| NUDT2 | 8509.0 |
| MDM4 | 8496.0 |
| RPL36AL | 8459.5 |
| CDKN1B | 8453.0 |
| DEDD2 | 8452.0 |
| RPL22L1 | 8449.0 |
| MT1A | 8411.0 |
| H2BC1 | 8383.0 |
| HSPB8 | 8359.0 |
| TUBAL3 | 8355.0 |
| ASF1A | 8338.0 |
| DYNLL2 | 8325.0 |
| ATP6V1E1 | 8281.0 |
| RPL31 | 8273.0 |
| FNIP1 | 8229.0 |
| PSMB4 | 8180.0 |
| RPS24 | 8170.0 |
| TP53 | 8108.0 |
| RPS23 | 8094.0 |
| H3C12 | 8052.0 |
| HSPA5 | 8033.0 |
| RPL26 | 8016.0 |
| TACO1 | 7999.0 |
| EXOSC9 | 7985.0 |
| TUBB4B | 7956.0 |
| RPS20 | 7907.0 |
| PSMD13 | 7901.0 |
| TXNIP | 7855.0 |
| DCTN6 | 7834.0 |
| NR1D1 | 7831.0 |
| H2AZ2 | 7814.0 |
| COX16 | 7805.0 |
| GPX1 | 7799.0 |
| TUBB3 | 7767.0 |
| NUP155 | 7761.0 |
| H2AC7 | 7754.5 |
| H2BC7 | 7754.5 |
| VENTX | 7728.0 |
| AKT1S1 | 7712.0 |
| PSME4 | 7705.0 |
| MAP2K3 | 7685.0 |
| UBB | 7674.0 |
| ARNT | 7661.0 |
| PSMB2 | 7641.0 |
| P4HB | 7631.0 |
| RPS29 | 7621.0 |
| TPP1 | 7512.0 |
| HIF3A | 7504.0 |
| DIS3 | 7503.0 |
| MTF1 | 7491.0 |
| HSPA8 | 7490.0 |
| UFD1 | 7487.0 |
| VEGFA | 7485.0 |
| CREB3L1 | 7451.0 |
| RPL34 | 7423.0 |
| RPS19 | 7419.0 |
| RPS3 | 7411.0 |
| LMNA | 7398.0 |
| PSMB11 | 7359.0 |
| RPL41 | 7335.0 |
| YIF1A | 7327.0 |
| RPL6 | 7304.0 |
| CDKN2A | 7282.0 |
| DNAJB11 | 7272.0 |
| H4C16 | 7260.0 |
| TUBA8 | 7215.0 |
| SIN3A | 7192.0 |
| PSMA6 | 7190.0 |
| RPS27A | 7120.0 |
| TLN1 | 7118.0 |
| HDGF | 7091.0 |
| PSMA1 | 7018.0 |
| KDM6B | 7004.0 |
| NLRP3 | 7003.0 |
| EDEM1 | 6990.0 |
| LIMD1 | 6962.0 |
| ANAPC11 | 6955.0 |
| CALR | 6943.0 |
| CDK2 | 6939.0 |
| RPL23 | 6935.0 |
| CRTC3 | 6919.0 |
| COX7C | 6918.0 |
| EXOSC4 | 6868.0 |
| RBBP4 | 6844.0 |
| SEH1L | 6838.0 |
| NUP35 | 6822.0 |
| TUBB8 | 6817.0 |
| ATP6V1B2 | 6805.0 |
| TUBB2B | 6768.0 |
| DDIT3 | 6748.0 |
| NUP85 | 6688.0 |
| PSMD3 | 6672.0 |
| H2AC8 | 6630.0 |
| MAP2K7 | 6542.0 |
| COX6C | 6519.0 |
| GSTA3 | 6492.0 |
| FAU | 6424.0 |
| RPL11 | 6414.0 |
| RPL21 | 6341.0 |
| NR3C1 | 6322.0 |
| CREB3 | 6310.0 |
| NUP37 | 6306.0 |
| ETS1 | 6283.0 |
| ACADVL | 6282.0 |
| DNAJA1 | 6253.0 |
| BACH1 | 6180.0 |
| MOV10 | 6170.0 |
| RPL13 | 6125.0 |
| H3-3B | 6110.0 |
| HELZ2 | 6090.0 |
| H2BC8 | 6087.0 |
| HSPH1 | 6083.0 |
| RRAGC | 6080.0 |
| RPS26 | 6058.0 |
| CREB1 | 6047.0 |
| RPS19BP1 | 6040.0 |
| MBTPS1 | 6010.0 |
| RPL7A | 5991.0 |
| TRIB3 | 5967.0 |
| CYBA | 5941.0 |
| H4C3 | 5935.0 |
| NUP43 | 5921.0 |
| RPS16 | 5896.0 |
| CTDSP2 | 5869.0 |
| ANAPC10 | 5865.0 |
| H4C1 | 5864.0 |
| PRDX1 | 5840.0 |
| HYOU1 | 5825.0 |
| RPL8 | 5822.0 |
| DCTN2 | 5812.0 |
| GCN1 | 5802.0 |
| CREB3L4 | 5801.0 |
| EGLN2 | 5790.0 |
| RB1 | 5745.0 |
| RPS7 | 5716.0 |
| PSMC1 | 5715.0 |
| NQO1 | 5699.0 |
| NFYC | 5655.0 |
| RPA1 | 5651.0 |
| NUP54 | 5644.0 |
| DNAJC2 | 5640.0 |
| PSMD2 | 5624.0 |
| MRE11 | 5620.0 |
| DEPDC5 | 5608.0 |
| H3C1 | 5598.0 |
| RPL26L1 | 5531.0 |
| PRDX6 | 5512.0 |
| ATP6V1A | 5492.0 |
| AGO4 | 5459.0 |
| RPS8 | 5431.0 |
| SMARCD3 | 5379.0 |
| CAPZA1 | 5374.0 |
| PSMA5 | 5362.0 |
| ANAPC2 | 5346.0 |
| CHD9 | 5318.0 |
| H1-5 | 5307.0 |
| RPL37A | 5292.0 |
| PHC1 | 5291.0 |
| PGD | 5272.0 |
| IMPACT | 5258.0 |
| HIRA | 5256.0 |
| PSMA4 | 5246.0 |
| RPL3L | 5206.0 |
| PSMC5 | 5193.0 |
| GOSR2 | 5176.0 |
| UBXN7 | 5134.0 |
| RPL13A | 5131.5 |
| H2BC5 | 5130.0 |
| HIF1AN | 5123.0 |
| HMGA2 | 5097.0 |
| NUP107 | 5069.0 |
| RPS10 | 5058.0 |
| CDKN1A | 5054.0 |
| H4C6 | 4952.0 |
| IDH1 | 4950.0 |
| TERF2 | 4935.0 |
| NDUFA4 | 4915.0 |
| RPL19 | 4913.0 |
| HIGD1A | 4899.0 |
| RPS18 | 4856.0 |
| TNFRSF21 | 4829.0 |
| SRPRB | 4813.0 |
| NUP88 | 4788.0 |
| RPL9 | 4760.0 |
| CASTOR1 | 4748.0 |
| H1-2 | 4724.0 |
| H3C4 | 4718.0 |
| RPS27 | 4711.0 |
| CSNK2A1 | 4697.0 |
| MT1F | 4691.0 |
| CEBPB | 4682.0 |
| NUP133 | 4676.0 |
| BMI1 | 4673.0 |
| ANAPC5 | 4671.0 |
| H2BC3 | 4658.0 |
| GSK3A | 4632.0 |
| H4C13 | 4630.0 |
| MT1X | 4628.0 |
| ATM | 4600.0 |
| HM13 | 4574.0 |
| H4C11 | 4553.0 |
| ATP6V0C | 4507.0 |
| RPS12 | 4501.0 |
| RPS6KA1 | 4484.0 |
| CUL7 | 4474.0 |
| RPL35 | 4434.0 |
| SESN1 | 4424.0 |
| DNAJA4 | 4361.0 |
| ATP6V1D | 4345.0 |
| PSMF1 | 4311.0 |
| MIOS | 4275.0 |
| SOD3 | 4274.0 |
| EXOSC3 | 4242.0 |
| PTGES3 | 4234.0 |
| PSMD1 | 4227.0 |
| RPL35A | 4218.0 |
| MAP3K5 | 4207.0 |
| RPL17 | 4202.0 |
| TNRC6B | 4201.0 |
| PSME3 | 4172.0 |
| ABCC1 | 4168.0 |
| MAPKAPK2 | 4162.0 |
| CSNK2A2 | 4122.0 |
| PSMC2 | 4088.0 |
| HIKESHI | 4086.0 |
| MAP1LC3B | 4080.0 |
| FNIP2 | 4046.0 |
| KICS2 | 4008.0 |
| HSF1 | 3970.0 |
| CAPZA2 | 3961.0 |
| H2BC10 | 3947.0 |
| PSMA8 | 3923.0 |
| PSMA7 | 3903.0 |
| PSME1 | 3866.0 |
| PSMA3 | 3850.0 |
| TATDN2 | 3828.0 |
| HERPUD1 | 3822.0 |
| LAMTOR5 | 3821.0 |
| HSP90AB1 | 3811.0 |
| COX6B1 | 3786.0 |
| H4C4 | 3785.0 |
| CBX2 | 3753.0 |
| NUP205 | 3738.0 |
| UBE2D2 | 3677.0 |
| CREBRF | 3663.0 |
| HIF1A | 3657.0 |
| HSPA4L | 3656.0 |
| ATF2 | 3606.0 |
| CCNA1 | 3593.0 |
| PRDX5 | 3588.0 |
| ADD1 | 3568.0 |
| NPRL2 | 3561.0 |
| SKP1 | 3534.0 |
| PSMB9 | 3459.0 |
| MAPK9 | 3453.0 |
| CDKN2C | 3429.0 |
| PPARA | 3412.0 |
| ZBTB17 | 3370.0 |
| ATP6V1B1 | 3349.0 |
| TCIRG1 | 3340.0 |
| TFDP2 | 3339.0 |
| RPSA | 3281.0 |
| H2BC17 | 3276.0 |
| BLVRB | 3265.0 |
| STAP2 | 3256.0 |
| RPL3 | 3240.0 |
| HMOX2 | 3213.0 |
| H1-4 | 3207.0 |
| CCNE2 | 3190.0 |
| ATP6V1E2 | 3127.0 |
| ACTR1A | 3117.0 |
| CDC27 | 3049.0 |
| EXOSC7 | 3025.0 |
| NOX4 | 3018.0 |
| EXTL2 | 3013.0 |
| H3C6 | 3009.0 |
| PSMC4 | 3004.0 |
| MT1E | 2978.0 |
| UBE2D3 | 2976.0 |
| PSMC3 | 2960.0 |
| H2AC6 | 2946.0 |
| PARN | 2863.0 |
| NUP42 | 2844.0 |
| RPL12 | 2822.0 |
| RRAGD | 2813.0 |
| NUP93 | 2792.0 |
| EHMT1 | 2779.0 |
| CA9 | 2753.0 |
| DNAJB9 | 2721.0 |
| NUP58 | 2703.0 |
| H3C8 | 2699.0 |
| RPS28 | 2669.0 |
| RANBP2 | 2651.0 |
| NCOA6 | 2647.0 |
| EIF2S1 | 2623.0 |
| CBX6 | 2581.0 |
| SEM1 | 2517.0 |
| USP46 | 2497.0 |
| RPL27A | 2494.0 |
| PGR | 2421.0 |
| RPL15 | 2382.0 |
| H2AC4 | 2379.0 |
| RPL32 | 2362.0 |
| MEF2C | 2335.0 |
| CDC26 | 2306.0 |
| FOS | 2247.0 |
| COX20 | 2175.0 |
| MAPKAPK5 | 2167.0 |
| RPS15A | 2095.0 |
| EIF2S2 | 2093.0 |
| DNAJC3 | 2083.0 |
| TGS1 | 2080.0 |
| H3-4 | 2030.0 |
| RPS25 | 1988.0 |
| CXXC1 | 1985.0 |
| ANAPC15 | 1950.0 |
| SOD1 | 1946.0 |
| ITFG2 | 1934.0 |
| CDC23 | 1927.0 |
| FKBP14 | 1925.0 |
| GSR | 1919.0 |
| NRIP1 | 1855.0 |
| DNAJA2 | 1838.0 |
| TXNRD1 | 1835.0 |
| TNIK | 1815.0 |
| MAPKAPK3 | 1801.0 |
| TINF2 | 1779.0 |
| RPLP1 | 1762.0 |
| LAMTOR1 | 1723.0 |
| HDAC3 | 1718.0 |
| IGFBP1 | 1703.0 |
| IL1A | 1611.0 |
| RING1 | 1572.0 |
| ETS2 | 1483.0 |
| RPL7 | 1442.0 |
| H3C2 | 1438.0 |
| CBX8 | 1425.0 |
| ACTR10 | 1402.0 |
| SURF1 | 1393.0 |
| HSP90AA1 | 1355.0 |
| H2BC11 | 1338.0 |
| EHMT2 | 1321.0 |
| COX6A1 | 1217.0 |
| MAP4K4 | 1194.0 |
| BRCA1 | 1120.0 |
| RPA2 | 1117.0 |
| CAPZB | 1024.0 |
| TUBA4A | 938.0 |
| SERP1 | 898.0 |
| WFS1 | 772.0 |
| CDC16 | 754.0 |
| YWHAE | 744.0 |
| VHL | 735.0 |
| TALDO1 | 727.0 |
| TUBA4B | 650.0 |
| PSMD11 | 620.0 |
| KDELR3 | 582.0 |
| SQSTM1 | 569.0 |
| H2AX | 499.0 |
| NPAS2 | 491.0 |
| STIP1 | 464.0 |
| PSMB8 | 447.0 |
| CRYBA4 | 410.0 |
| PDIA6 | 395.0 |
| NFYA | 361.0 |
| HSP90B1 | 354.0 |
| ASNS | 351.0 |
| GSTP1 | 326.0 |
| H2BC15 | 240.0 |
| DYNC1LI1 | 233.0 |
| MDM2 | 219.0 |
| BTRC | 216.0 |
| CBX4 | 205.0 |
| DCTN3 | 114.0 |
| DPP3 | 105.0 |
| EED | 94.0 |
| SLC7A11 | 77.0 |
| FZR1 | 16.0 |
| PSMA2 | -85.0 |
| EXTL1 | -113.0 |
| EXOSC8 | -119.0 |
| CAMK2B | -127.0 |
| RPL5 | -139.0 |
| DYNC1I1 | -202.0 |
| APOB | -225.0 |
| NCF4 | -238.0 |
| COX5A | -245.0 |
| MTOR | -250.0 |
| ANAPC4 | -310.0 |
| NUP98 | -351.0 |
| H2AZ1 | -360.0 |
| DNAJB6 | -376.0 |
| HSPA2 | -408.0 |
| DYNC1I2 | -440.0 |
| RAI1 | -472.0 |
| HMGA1 | -496.0 |
| HSPA4 | -522.0 |
| H3C3 | -546.0 |
| TUBB1 | -584.0 |
| POT1 | -662.0 |
| H2AC20 | -674.0 |
| TXNRD2 | -701.0 |
| EXTL3 | -742.0 |
| NPRL3 | -752.0 |
| MAPK1 | -857.0 |
| PSMD14 | -865.0 |
| BAG2 | -893.0 |
| GCLC | -931.0 |
| LAMTOR3 | -947.0 |
| PSMD6 | -961.0 |
| RPS2 | -1028.0 |
| NOTCH1 | -1033.0 |
| ANAPC1 | -1043.0 |
| GCLM | -1049.0 |
| TXN2 | -1051.0 |
| XPO1 | -1083.0 |
| DCTN5 | -1108.0 |
| UBN1 | -1139.0 |
| COX14 | -1185.0 |
| CREB3L2 | -1197.0 |
| CDK6 | -1199.0 |
| RXRA | -1218.0 |
| RLN1 | -1243.0 |
| NOX5 | -1266.0 |
| PSMB7 | -1294.0 |
| LMNB1 | -1316.0 |
| PLA2G4B | -1322.0 |
| MAPK7 | -1357.0 |
| UBE2S | -1361.0 |
| EIF2AK4 | -1363.0 |
| H2BC6 | -1396.0 |
| ALB | -1412.0 |
| AGO3 | -1413.0 |
| NDC1 | -1433.0 |
| TBL1XR1 | -1440.0 |
| EXOSC6 | -1460.0 |
| ACD | -1494.5 |
| CAT | -1504.0 |
| HBB | -1563.0 |
| BMAL1 | -1600.0 |
| HSPB2 | -1626.0 |
| EIF2AK1 | -1643.0 |
| RPS14 | -1691.0 |
| MAFK | -1712.0 |
| NUP188 | -1877.0 |
| SLC38A9 | -1912.0 |
| PRDX2 | -1921.0 |
| CSRP1 | -1985.0 |
| MAP2K4 | -2008.0 |
| ATP6V1H | -2022.0 |
| MAP2K6 | -2038.0 |
| RPL30 | -2061.0 |
| CUL2 | -2081.0 |
| H2BC4 | -2094.0 |
| WDR59 | -2110.0 |
| H2BC12 | -2115.0 |
| TFDP1 | -2156.0 |
| ATF3 | -2158.0 |
| MAPK11 | -2236.0 |
| PSMB10 | -2290.0 |
| ATOX1 | -2291.0 |
| HSPA12B | -2293.0 |
| E2F3 | -2343.0 |
| EP300 | -2354.0 |
| MT1M | -2359.0 |
| PSMB6 | -2408.0 |
| CREBBP | -2409.0 |
| EZH2 | -2415.0 |
| TNRC6A | -2432.0 |
| CUL1 | -2437.0 |
| AKT2 | -2480.0 |
| CUL3 | -2503.0 |
| UBE2C | -2539.0 |
| AKT1 | -2548.0 |
| CRTC2 | -2557.0 |
| PSMD9 | -2570.0 |
| RPS5 | -2579.0 |
| SEC31A | -2590.0 |
| MYC | -2593.0 |
| COX18 | -2600.0 |
| CCL2 | -2609.0 |
| ATP6V0D1 | -2636.0 |
| UBE2E1 | -2647.0 |
| RPS6 | -2673.0 |
| ATP6V1C2 | -2734.0 |
| AAAS | -2839.0 |
| RPS6KA2 | -2842.0 |
| BAG3 | -2895.0 |
| EEF1A1 | -2905.0 |
| NPLOC4 | -2913.0 |
| RORA | -2965.0 |
| COX5B | -3104.0 |
| RPL39L | -3132.0 |
| TERF1 | -3138.0 |
| DCSTAMP | -3165.0 |
| GFPT1 | -3191.0 |
| NR3C2 | -3257.0 |
| SP1 | -3275.0 |
| MAPK10 | -3279.0 |
| RPL37 | -3282.0 |
| GRB10 | -3358.0 |
| PHC3 | -3360.0 |
| GML | -3372.0 |
| DCP2 | -3374.0 |
| GPX5 | -3388.0 |
| NUP153 | -3416.0 |
| SIRT1 | -3421.0 |
| HSPA9 | -3436.0 |
| CCNA2 | -3495.0 |
| RAE1 | -3503.0 |
| DYNLL1 | -3541.0 |
| HSPA14 | -3558.0 |
| IFNB1 | -3599.0 |
| CARM1 | -3614.0 |
| DNAJB1 | -3616.0 |
| CCS | -3658.0 |
| TNRC6C | -3711.0 |
| ME1 | -3731.0 |
| UBA52 | -3755.0 |
| ANAPC7 | -3780.0 |
| ST13 | -3783.0 |
| TKT | -3795.0 |
| CCAR2 | -3837.0 |
| NBN | -3893.0 |
| TERF2IP | -3905.0 |
| SCMH1 | -3933.0 |
| CAMK2D | -3981.0 |
| PALB2 | -4029.0 |
| RHEB | -4039.0 |
| SCO1 | -4041.0 |
| AJUBA | -4043.0 |
| POM121C | -4045.0 |
| SCO2 | -4149.0 |
| RPS15 | -4150.0 |
| MAFG | -4154.0 |
| HSPA1L | -4213.0 |
| COX7A2L | -4311.0 |
| E2F2 | -4314.0 |
| EP400 | -4349.0 |
| TUBA1C | -4357.0 |
| RRAGA | -4390.0 |
| NCOR1 | -4394.0 |
| CLEC1B | -4407.0 |
| WDR24 | -4414.0 |
| NCOR2 | -4436.0 |
| FLCN | -4462.0 |
| TUBA1B | -4469.0 |
| ANAPC16 | -4502.0 |
| ATR | -4506.0 |
| EPAS1 | -4517.0 |
| CEBPG | -4609.0 |
| RPL24 | -4644.0 |
| RPS9 | -4650.0 |
| PSMB5 | -4687.0 |
| GPX2 | -4690.0 |
| NCOA2 | -4724.0 |
| SSR1 | -4735.0 |
| SKP2 | -4745.0 |
| FBXL17 | -4829.0 |
| H2BC9 | -4907.5 |
| H3C7 | -4907.5 |
| H4C5 | -4941.0 |
| HSPA12A | -5002.0 |
| HMOX1 | -5069.0 |
| RPL4 | -5128.0 |
| COX19 | -5160.0 |
| KEAP1 | -5174.0 |
| APOA1 | -5192.0 |
| PSMD7 | -5198.0 |
| CLOCK | -5240.0 |
| TUBA3D | -5264.0 |
| RPL27 | -5306.0 |
| PSMD4 | -5337.0 |
| COX8A | -5390.0 |
| ATF5 | -5392.0 |
| UBE2D1 | -5394.0 |
| PRKCD | -5412.0 |
| DCTN1 | -5418.0 |
| RPL18A | -5425.0 |
| FKBP5 | -5427.0 |
| MAPK3 | -5444.0 |
| NUP214 | -5472.0 |
| CRYAB | -5546.0 |
| AKT3 | -5586.0 |
| SEC13 | -5670.0 |
| RPL22 | -5765.0 |
| H2BC21 | -5773.0 |
| RPLP2 | -5777.0 |
| HSPA1B | -5824.0 |
| PSMB1 | -5858.0 |
| ATP6V0B | -5878.0 |
| RPS27L | -5945.0 |
| CAMK2G | -6002.0 |
| GSK3B | -6007.0 |
| DYNC1H1 | -6092.0 |
| NUP50 | -6183.0 |
| CABIN1 | -6185.0 |
| MT3 | -6266.0 |
| PRDX3 | -6401.0 |
| RAD50 | -6431.0 |
| EGLN1 | -6462.0 |
| HSPA1A | -6507.0 |
| NFYB | -6538.0 |
| RNF2 | -6542.0 |
| CAMK2A | -6562.0 |
| KPTN | -6603.0 |
| NUP210 | -6637.0 |
| H2BC26 | -6695.0 |
| PHC2 | -6705.0 |
| EXOSC2 | -6711.0 |
| FABP1 | -6712.0 |
| SLC46A1 | -6779.0 |
| MLST8 | -6804.0 |
| VCP | -7056.0 |
| NFE2L2 | -7067.0 |
| MUL1 | -7132.0 |
| SRPRA | -7160.0 |
| NUP160 | -7169.0 |
| ATF6 | -7190.0 |
| SH3BP4 | -7254.0 |
| NUP62 | -7266.0 |
| NFKB1 | -7273.0 |
| MYDGF | -7315.0 |
| PDIA5 | -7319.0 |
| PPP1R15A | -7333.0 |
| AQP8 | -7352.0 |
| SOD2 | -7470.0 |
| SZT2 | -7526.0 |
| FKBP4 | -7549.0 |
| PTK6 | -7557.0 |
| TUBB4A | -7633.0 |
| GPX6 | -7715.0 |
| PSMD8 | -7723.0 |
| CHAC1 | -7755.0 |
| WTIP | -7760.0 |
| IGFBP7 | -7794.0 |
| SRXN1 | -7837.0 |
| ERO1A | -7865.0 |
| CITED2 | -7882.0 |
| SERPINH1 | -8010.0 |
| RPTOR | -8028.0 |
| TUBA1A | -8056.0 |
| RPA3 | -8086.0 |
| RELA | -8093.0 |
| RPL36 | -8155.0 |
| CRTC1 | -8174.0 |
| CAPZA3 | -8175.0 |
| H1-1 | -8290.0 |
| BMT2 | -8482.0 |
| HSBP1 | -8525.0 |
| SIN3B | -8543.0 |
| ATP6V1G3 | -8586.0 |
| H2AC14 | -8606.0 |
| RPS11 | -8626.0 |
| EGLN3 | -8643.0 |
| PPARGC1A | -8665.0 |
| MAPK8 | -8692.0 |
| H2BC14 | -8730.0 |
| NCOA1 | -8848.0 |
| TPR | -9043.0 |
| MIR24-1 | -9122.0 |
| MINK1 | -9125.0 |
| MT2A | -9208.0 |
| H4C9 | -9282.0 |
| MT4 | -9390.0 |
| TUBB2A | -9511.0 |
| PSMD5 | -9524.0 |
| ARFGAP1 | -9536.0 |
| HSPA6 | -9683.0 |
| MT1B | -9753.0 |
| CCNE1 | -9930.0 |
| RPL10L | -10090.0 |
| TUBA3C | -10220.0 |
| H2AC18 | -10224.5 |
| H2AC19 | -10224.5 |
| GSTA1 | -10408.0 |
| TUBA3E | -10574.0 |
REACTOME_TRANSLATION
| 1152 | |
|---|---|
| set | REACTOME_TRANSLATION |
| setSize | 278 |
| pANOVA | 3.48e-09 |
| s.dist | 0.206 |
| p.adjustANOVA | 1.62e-06 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| SEC61B | 10362 |
| MRPL4 | 10269 |
| RPL14 | 10215 |
| EEF1A2 | 10153 |
| RPL18 | 10082 |
| RPL10A | 10035 |
| MRPL39 | 10024 |
| EIF4A1 | 10017 |
| SRP14 | 9909 |
| RPL23A | 9830 |
| RPS13 | 9737 |
| PARS2 | 9683 |
| MRPL18 | 9632 |
| MRPL34 | 9629 |
| SSR3 | 9615 |
| MRPS18A | 9592 |
| MTRF1L | 9580 |
| MRPL22 | 9550 |
| MRPL11 | 9548 |
| RPL38 | 9474 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SEC61B | 10362.0 |
| MRPL4 | 10269.0 |
| RPL14 | 10215.0 |
| EEF1A2 | 10153.0 |
| RPL18 | 10082.0 |
| RPL10A | 10035.0 |
| MRPL39 | 10024.0 |
| EIF4A1 | 10017.0 |
| SRP14 | 9909.0 |
| RPL23A | 9830.0 |
| RPS13 | 9737.0 |
| PARS2 | 9683.0 |
| MRPL18 | 9632.0 |
| MRPL34 | 9629.0 |
| SSR3 | 9615.0 |
| MRPS18A | 9592.0 |
| MTRF1L | 9580.0 |
| MRPL22 | 9550.0 |
| MRPL11 | 9548.0 |
| RPL38 | 9474.0 |
| ERAL1 | 9446.0 |
| CHCHD1 | 9415.0 |
| FARSA | 9323.0 |
| RPS21 | 9255.0 |
| RPLP0 | 9213.0 |
| MRPL50 | 9212.0 |
| DDOST | 9201.0 |
| RPL29 | 9165.0 |
| DARS2 | 9078.0 |
| RPS3A | 8946.0 |
| RPL28 | 8875.0 |
| SRP72 | 8776.0 |
| EIF3F | 8569.0 |
| PABPC1 | 8543.0 |
| RPL36AL | 8459.5 |
| RPL22L1 | 8449.0 |
| MRPS21 | 8399.0 |
| MRPL21 | 8387.0 |
| MRPL38 | 8331.0 |
| RPL31 | 8273.0 |
| EIF3E | 8263.0 |
| RPS24 | 8170.0 |
| MRPS30 | 8160.0 |
| RPS23 | 8094.0 |
| SRP9 | 8071.0 |
| RPL26 | 8016.0 |
| SRP54 | 8000.0 |
| MRPS18C | 7965.0 |
| MRPL53 | 7941.0 |
| RPS20 | 7907.0 |
| RPN1 | 7882.0 |
| EIF2B1 | 7775.0 |
| SSR2 | 7765.0 |
| MTIF3 | 7702.0 |
| RPS29 | 7621.0 |
| EIF3D | 7612.0 |
| EIF4E | 7566.0 |
| EIF3K | 7541.0 |
| EPRS1 | 7532.0 |
| EIF3J | 7482.0 |
| RPL34 | 7423.0 |
| RPS19 | 7419.0 |
| RPS3 | 7411.0 |
| RPL41 | 7335.0 |
| RPL6 | 7304.0 |
| MRPS11 | 7236.0 |
| TARS2 | 7230.0 |
| RPS27A | 7120.0 |
| TARS1 | 7107.0 |
| EEF1D | 7050.0 |
| EIF4H | 6954.0 |
| MRPL1 | 6951.0 |
| RPL23 | 6935.0 |
| EEF1G | 6755.0 |
| AARS1 | 6623.0 |
| MRPL40 | 6552.0 |
| FAU | 6424.0 |
| SARS2 | 6418.0 |
| RPL11 | 6414.0 |
| MRPS12 | 6406.0 |
| NARS2 | 6364.0 |
| RPL21 | 6341.0 |
| MRPL55 | 6172.0 |
| RPL13 | 6125.0 |
| MRPL49 | 6096.0 |
| RPS26 | 6058.0 |
| SPCS2 | 5997.0 |
| RPL7A | 5991.0 |
| RPS16 | 5896.0 |
| RPL8 | 5822.0 |
| SEC11A | 5794.0 |
| VARS2 | 5734.0 |
| TSFM | 5728.0 |
| RPS7 | 5716.0 |
| MRPL51 | 5679.0 |
| TRMT112 | 5611.0 |
| MRPL15 | 5561.0 |
| EIF4EBP1 | 5542.0 |
| RPL26L1 | 5531.0 |
| MRPL16 | 5529.0 |
| EIF5B | 5527.0 |
| MRPL2 | 5468.0 |
| MRPL3 | 5458.0 |
| RPS8 | 5431.0 |
| MRPL24 | 5413.0 |
| PTCD3 | 5334.0 |
| EIF2B5 | 5319.0 |
| PPA2 | 5295.0 |
| RPL37A | 5292.0 |
| MTIF2 | 5289.0 |
| MRPL12 | 5252.0 |
| RPL3L | 5206.0 |
| OXA1L | 5185.0 |
| SEC61G | 5145.0 |
| RPL13A | 5131.5 |
| MRPL17 | 5101.0 |
| RPS10 | 5058.0 |
| EIF2B3 | 4977.0 |
| MRPL48 | 4966.0 |
| RPL19 | 4913.0 |
| RPS18 | 4856.0 |
| SEC61A1 | 4835.0 |
| SRPRB | 4813.0 |
| RPL9 | 4760.0 |
| MRPS22 | 4754.0 |
| RPS27 | 4711.0 |
| MRPS10 | 4669.0 |
| RPS12 | 4501.0 |
| MRPL36 | 4481.0 |
| RPL35 | 4434.0 |
| MRPL28 | 4400.0 |
| RPL35A | 4218.0 |
| RPL17 | 4202.0 |
| TRAM1 | 3904.0 |
| MRPL33 | 3751.0 |
| MRPL30 | 3667.0 |
| EEF1E1 | 3554.0 |
| MRPL47 | 3471.0 |
| VARS1 | 3315.0 |
| AIMP1 | 3311.0 |
| RPSA | 3281.0 |
| EARS2 | 3269.0 |
| RPL3 | 3240.0 |
| MRPL14 | 3234.0 |
| EIF4A2 | 3184.0 |
| SRP19 | 2954.0 |
| TUFM | 2923.0 |
| MRPS27 | 2911.0 |
| MRRF | 2907.0 |
| FARSB | 2883.0 |
| RPL12 | 2822.0 |
| MRPS23 | 2802.0 |
| EIF2B2 | 2764.0 |
| WARS2 | 2743.0 |
| RPS28 | 2669.0 |
| EIF2S1 | 2623.0 |
| MRPS18B | 2549.0 |
| RPL27A | 2494.0 |
| RPL15 | 2382.0 |
| RPL32 | 2362.0 |
| RPS15A | 2095.0 |
| EIF2S2 | 2093.0 |
| RPS25 | 1988.0 |
| MRPL20 | 1791.0 |
| RPLP1 | 1762.0 |
| MRPS34 | 1629.0 |
| APEH | 1622.0 |
| SEC11C | 1578.0 |
| EIF4G1 | 1551.0 |
| RPL7 | 1442.0 |
| MRPL52 | 1349.0 |
| IARS1 | 1216.0 |
| EIF2B4 | 1214.0 |
| DAP3 | 1170.0 |
| MRPL13 | 1146.0 |
| SPCS1 | 1097.0 |
| GADD45GIP1 | 980.0 |
| MRPS31 | 888.0 |
| MRPL32 | 849.0 |
| YARS2 | 839.0 |
| MRPL37 | 665.0 |
| WARS1 | 653.0 |
| EEF2 | 562.0 |
| MARS2 | 555.0 |
| MRPS9 | 430.0 |
| MRPL23 | 218.0 |
| EEF1B2 | 213.0 |
| EIF3H | 170.0 |
| RPL5 | -139.0 |
| MRPS15 | -207.0 |
| MRPL46 | -257.0 |
| MRPS25 | -267.0 |
| LARS1 | -758.0 |
| EIF3B | -862.0 |
| RPS2 | -1028.0 |
| MRPS24 | -1096.0 |
| GARS1 | -1329.0 |
| YARS1 | -1519.0 |
| NARS1 | -1528.0 |
| AIMP2 | -1548.0 |
| MRPL10 | -1555.0 |
| RPS14 | -1691.0 |
| RPL30 | -2061.0 |
| SRP68 | -2063.0 |
| MRPL44 | -2066.0 |
| DARS1 | -2348.0 |
| GSPT1 | -2497.0 |
| ETF1 | -2575.0 |
| RPS5 | -2579.0 |
| RPS6 | -2673.0 |
| LARS2 | -2755.0 |
| MRPL19 | -2779.0 |
| MRPS7 | -2845.0 |
| EEF1A1 | -2905.0 |
| RPL39L | -3132.0 |
| MRPL35 | -3134.0 |
| RPL37 | -3282.0 |
| MRPS2 | -3289.0 |
| EIF4B | -3542.0 |
| RARS2 | -3652.0 |
| MRPS14 | -3653.0 |
| MTFMT | -3662.0 |
| MRPS35 | -3702.0 |
| UBA52 | -3755.0 |
| MRPL9 | -3811.0 |
| CARS2 | -3841.0 |
| MRPL57 | -3852.0 |
| SEC61A2 | -4055.0 |
| RPS15 | -4150.0 |
| MRPS28 | -4158.0 |
| GFM1 | -4289.0 |
| MRPS5 | -4437.0 |
| EIF5 | -4490.0 |
| CARS1 | -4552.0 |
| MRPS26 | -4590.0 |
| RPL24 | -4644.0 |
| RPS9 | -4650.0 |
| GFM2 | -4667.0 |
| SSR1 | -4735.0 |
| MRPL54 | -4776.0 |
| KARS1 | -4792.0 |
| MRPS16 | -4916.0 |
| HARS2 | -4945.0 |
| PPA1 | -5013.0 |
| IARS2 | -5031.0 |
| EIF3G | -5119.0 |
| RPL4 | -5128.0 |
| MRPL42 | -5143.0 |
| RPL27 | -5306.0 |
| RPL18A | -5425.0 |
| MRPL27 | -5606.0 |
| MRPL43 | -5710.0 |
| RPL22 | -5765.0 |
| RPLP2 | -5777.0 |
| AURKAIP1 | -5796.0 |
| RPS27L | -5945.0 |
| EIF3L | -5990.0 |
| MRPS33 | -6010.0 |
| RARS1 | -6091.0 |
| MRPS6 | -6256.0 |
| HARS1 | -6678.0 |
| SRPRA | -7160.0 |
| N6AMT1 | -7185.0 |
| MRPL41 | -7204.0 |
| FARS2 | -7236.0 |
| AARS2 | -7281.0 |
| EIF3M | -7387.0 |
| RPN2 | -7620.0 |
| MRPL58 | -7640.0 |
| EIF3I | -7728.0 |
| EIF3A | -7810.0 |
| RPL36 | -8155.0 |
| RPS11 | -8626.0 |
| MARS1 | -8887.0 |
| MRPS17 | -9517.0 |
| SPCS3 | -9800.0 |
| MRPL45 | -10053.0 |
| RPL10L | -10090.0 |
REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS
| 1364 | |
|---|---|
| set | REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS |
| setSize | 161 |
| pANOVA | 3.95e-09 |
| s.dist | 0.269 |
| p.adjustANOVA | 1.62e-06 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| ELOB | 10991 |
| PSMD12 | 10325 |
| RPL14 | 10215 |
| RPL18 | 10082 |
| RPL10A | 10035 |
| PSMC6 | 9977 |
| PSMB3 | 9858 |
| RPL23A | 9830 |
| RPS13 | 9737 |
| RBM8A | 9578 |
| UBC | 9476 |
| RPL38 | 9474 |
| ELOC | 9413 |
| RBX1 | 9293 |
| RPS21 | 9255 |
| RPLP0 | 9213 |
| RPL29 | 9165 |
| RPS3A | 8946 |
| LDB1 | 8879 |
| RPL28 | 8875 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ELOB | 10991.0 |
| PSMD12 | 10325.0 |
| RPL14 | 10215.0 |
| RPL18 | 10082.0 |
| RPL10A | 10035.0 |
| PSMC6 | 9977.0 |
| PSMB3 | 9858.0 |
| RPL23A | 9830.0 |
| RPS13 | 9737.0 |
| RBM8A | 9578.0 |
| UBC | 9476.0 |
| RPL38 | 9474.0 |
| ELOC | 9413.0 |
| RBX1 | 9293.0 |
| RPS21 | 9255.0 |
| RPLP0 | 9213.0 |
| RPL29 | 9165.0 |
| RPS3A | 8946.0 |
| LDB1 | 8879.0 |
| RPL28 | 8875.0 |
| PSME2 | 8685.0 |
| DAG1 | 8634.0 |
| ROBO3 | 8567.0 |
| PABPC1 | 8543.0 |
| RPL36AL | 8459.5 |
| RPL22L1 | 8449.0 |
| RPL31 | 8273.0 |
| PSMB4 | 8180.0 |
| RPS24 | 8170.0 |
| RPS23 | 8094.0 |
| RPL26 | 8016.0 |
| LHX3 | 8002.0 |
| RPS20 | 7907.0 |
| PSMD13 | 7901.0 |
| UPF2 | 7759.0 |
| PSME4 | 7705.0 |
| UBB | 7674.0 |
| PSMB2 | 7641.0 |
| RPS29 | 7621.0 |
| RPL34 | 7423.0 |
| RPS19 | 7419.0 |
| RPS3 | 7411.0 |
| PSMB11 | 7359.0 |
| RPL41 | 7335.0 |
| RPL6 | 7304.0 |
| PSMA6 | 7190.0 |
| RPS27A | 7120.0 |
| PSMA1 | 7018.0 |
| RPL23 | 6935.0 |
| LHX9 | 6785.0 |
| PSMD3 | 6672.0 |
| FAU | 6424.0 |
| EIF4A3 | 6420.0 |
| RPL11 | 6414.0 |
| RPL21 | 6341.0 |
| RPL13 | 6125.0 |
| RPS26 | 6058.0 |
| RPL7A | 5991.0 |
| RPS16 | 5896.0 |
| RPL8 | 5822.0 |
| RPS7 | 5716.0 |
| PSMC1 | 5715.0 |
| NCBP1 | 5705.0 |
| PSMD2 | 5624.0 |
| RPL26L1 | 5531.0 |
| RPS8 | 5431.0 |
| USP33 | 5423.0 |
| PSMA5 | 5362.0 |
| RPL37A | 5292.0 |
| PSMA4 | 5246.0 |
| RPL3L | 5206.0 |
| PSMC5 | 5193.0 |
| RPL13A | 5131.5 |
| RPS10 | 5058.0 |
| LHX4 | 4938.0 |
| RPL19 | 4913.0 |
| RPS18 | 4856.0 |
| RPL9 | 4760.0 |
| RPS27 | 4711.0 |
| LHX2 | 4613.0 |
| RNPS1 | 4528.0 |
| RPS12 | 4501.0 |
| ISL1 | 4475.0 |
| RPL35 | 4434.0 |
| PSMF1 | 4311.0 |
| PSMD1 | 4227.0 |
| RPL35A | 4218.0 |
| RPL17 | 4202.0 |
| PSME3 | 4172.0 |
| PSMC2 | 4088.0 |
| CASC3 | 4044.0 |
| PSMA8 | 3923.0 |
| PSMA7 | 3903.0 |
| PSME1 | 3866.0 |
| PSMA3 | 3850.0 |
| PSMB9 | 3459.0 |
| RPSA | 3281.0 |
| RPL3 | 3240.0 |
| PSMC4 | 3004.0 |
| PSMC3 | 2960.0 |
| MSI1 | 2848.0 |
| RPL12 | 2822.0 |
| RPS28 | 2669.0 |
| SEM1 | 2517.0 |
| RPL27A | 2494.0 |
| RPL15 | 2382.0 |
| RPL32 | 2362.0 |
| RPS15A | 2095.0 |
| RPS25 | 1988.0 |
| RPLP1 | 1762.0 |
| EIF4G1 | 1551.0 |
| RPL7 | 1442.0 |
| PSMD11 | 620.0 |
| PSMB8 | 447.0 |
| PSMA2 | -85.0 |
| RPL5 | -139.0 |
| PSMD14 | -865.0 |
| PSMD6 | -961.0 |
| RPS2 | -1028.0 |
| PSMB7 | -1294.0 |
| RPS14 | -1691.0 |
| MAGOHB | -1800.0 |
| RPL30 | -2061.0 |
| CUL2 | -2081.0 |
| PSMB10 | -2290.0 |
| PSMB6 | -2408.0 |
| GSPT1 | -2497.0 |
| PSMD9 | -2570.0 |
| ETF1 | -2575.0 |
| RPS5 | -2579.0 |
| RPS6 | -2673.0 |
| RPL39L | -3132.0 |
| NCBP2 | -3139.0 |
| RPL37 | -3282.0 |
| ROBO2 | -3642.0 |
| UBA52 | -3755.0 |
| RPS15 | -4150.0 |
| SLIT2 | -4401.0 |
| RPL24 | -4644.0 |
| RPS9 | -4650.0 |
| PSMB5 | -4687.0 |
| RPL4 | -5128.0 |
| PSMD7 | -5198.0 |
| SLIT1 | -5260.0 |
| RPL27 | -5306.0 |
| HOXA2 | -5327.0 |
| PSMD4 | -5337.0 |
| RPL18A | -5425.0 |
| RPL22 | -5765.0 |
| RPLP2 | -5777.0 |
| PSMB1 | -5858.0 |
| ROBO1 | -5895.0 |
| RPS27L | -5945.0 |
| ZSWIM8 | -7205.0 |
| PSMD8 | -7723.0 |
| UPF3A | -7770.0 |
| RPL36 | -8155.0 |
| RPS11 | -8626.0 |
| MAGOH | -9309.0 |
| PSMD5 | -9524.0 |
| RPL10L | -10090.0 |
REACTOME_SENSORY_PERCEPTION
| 1581 | |
|---|---|
| set | REACTOME_SENSORY_PERCEPTION |
| setSize | 555 |
| pANOVA | 7.16e-09 |
| s.dist | -0.144 |
| p.adjustANOVA | 2.35e-06 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| OR6C6 | -10854 |
| OR52R1 | -10810 |
| OR51F1 | -10793 |
| OR5H1 | -10775 |
| TAS2R41 | -10767 |
| OR2A5 | -10736 |
| OR5AP2 | -10728 |
| OR51E1 | -10686 |
| OR5J2 | -10685 |
| OR51T1 | -10658 |
| OR8D2 | -10621 |
| AKR1C1 | -10600 |
| OR8I2 | -10590 |
| OR2G6 | -10560 |
| TAS2R20 | -10547 |
| OR2M3 | -10544 |
| OR52N1 | -10535 |
| OR5T3 | -10534 |
| OR13J1 | -10527 |
| OR2B6 | -10525 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| OR6C6 | -10854.0 |
| OR52R1 | -10810.0 |
| OR51F1 | -10793.0 |
| OR5H1 | -10775.0 |
| TAS2R41 | -10767.0 |
| OR2A5 | -10736.0 |
| OR5AP2 | -10728.0 |
| OR51E1 | -10686.0 |
| OR5J2 | -10685.0 |
| OR51T1 | -10658.0 |
| OR8D2 | -10621.0 |
| AKR1C1 | -10600.0 |
| OR8I2 | -10590.0 |
| OR2G6 | -10560.0 |
| TAS2R20 | -10547.0 |
| OR2M3 | -10544.0 |
| OR52N1 | -10535.0 |
| OR5T3 | -10534.0 |
| OR13J1 | -10527.0 |
| OR2B6 | -10525.0 |
| OR1C1 | -10524.0 |
| OR2G3 | -10474.0 |
| APOC2 | -10462.0 |
| OR4E2 | -10415.0 |
| OR5AN1 | -10409.0 |
| OR2M4 | -10400.0 |
| OR5M8 | -10396.0 |
| OR13G1 | -10296.0 |
| OR2A2 | -10294.0 |
| OR51M1 | -10293.0 |
| OR2L3 | -10291.0 |
| AKR1B10 | -10278.0 |
| OR5K2 | -10242.0 |
| OR5K4 | -10208.0 |
| RBP3 | -10206.0 |
| OR1N1 | -10192.0 |
| OR52D1 | -10186.0 |
| OR5T2 | -10185.0 |
| OR1Q1 | -10165.0 |
| OR6C76 | -10102.0 |
| OR2L8 | -10078.0 |
| TAS2R43 | -10055.0 |
| TAS2R14 | -9997.0 |
| OR8B4 | -9970.0 |
| OR5B2 | -9955.0 |
| OR10A6 | -9893.0 |
| OR5I1 | -9886.0 |
| OR6K2 | -9882.0 |
| OR6Y1 | -9867.0 |
| TAS2R10 | -9845.0 |
| OR5M11 | -9819.0 |
| RTP1 | -9782.0 |
| OR2A12 | -9772.0 |
| OR6P1 | -9724.0 |
| OR5B21 | -9694.0 |
| OR10J5 | -9671.0 |
| TAS2R39 | -9668.0 |
| OR51D1 | -9654.0 |
| GUCA1C | -9573.0 |
| OR51I2 | -9558.0 |
| OR51L1 | -9553.0 |
| STRA6 | -9527.0 |
| OR12D2 | -9526.0 |
| OR5AR1 | -9519.0 |
| OR5B12 | -9516.0 |
| RHO | -9493.0 |
| ADCY3 | -9478.0 |
| OR5L1 | -9458.0 |
| OR10J3 | -9366.0 |
| OR2C3 | -9336.0 |
| OR11A1 | -9335.0 |
| OR5P3 | -9296.0 |
| CNGA4 | -9273.0 |
| OR4M1 | -9255.0 |
| TAS2R8 | -9248.0 |
| HSD17B6 | -9223.0 |
| RBP2 | -9221.0 |
| TAS2R40 | -9183.0 |
| OR10K2 | -9179.0 |
| BCO1 | -9154.0 |
| OR7D2 | -9104.0 |
| OR52E6 | -9090.0 |
| CLPS | -9086.0 |
| OR8H3 | -9077.0 |
| OR4D10 | -9071.0 |
| OR6S1 | -9051.0 |
| OR10K1 | -9049.0 |
| OR52J3 | -9030.0 |
| OR6F1 | -9022.0 |
| OR2AK2 | -9009.0 |
| OR6C2 | -8988.0 |
| OR10A5 | -8979.0 |
| OR51S1 | -8964.0 |
| HSPG2 | -8928.0 |
| OR7A5 | -8870.0 |
| GPIHBP1 | -8847.0 |
| TAS2R5 | -8843.0 |
| OR1L3 | -8823.0 |
| MYO3A | -8796.0 |
| OR13D1 | -8765.0 |
| OR10H4 | -8756.0 |
| LDLR | -8742.0 |
| OR6V1 | -8740.0 |
| OR2T27 | -8736.0 |
| OR52H1 | -8723.0 |
| OR5C1 | -8714.0 |
| OR4D11 | -8690.0 |
| OPN1SW | -8602.0 |
| OR2T6 | -8486.0 |
| OR2AT4 | -8475.0 |
| OR10A3 | -8419.0 |
| OR2M2 | -8400.0 |
| OR5A2 | -8347.0 |
| OR4C15 | -8323.0 |
| OR5L2 | -8315.0 |
| OR51A7 | -8310.0 |
| OR7G1 | -8248.0 |
| PCLO | -8204.0 |
| OR14C36 | -8185.0 |
| OR56A1 | -8128.0 |
| OR8K5 | -8103.0 |
| TAS2R13 | -8081.0 |
| OR5P2 | -8029.0 |
| OR5D14 | -8023.0 |
| TAS2R16 | -8003.0 |
| SCN3A | -8000.0 |
| OR5V1 | -7877.0 |
| OR52E2 | -7855.0 |
| LRP8 | -7852.0 |
| SDC2 | -7848.0 |
| OR10H1 | -7826.0 |
| OR8U8 | -7784.0 |
| OTOGL | -7741.0 |
| ITPR3 | -7685.0 |
| OR2Y1 | -7677.0 |
| SDC4 | -7669.0 |
| OR8D1 | -7654.0 |
| OR8J3 | -7649.0 |
| OR8B12 | -7632.0 |
| OR2L13 | -7590.0 |
| OR10G7 | -7584.0 |
| TMC2 | -7539.0 |
| EPS8 | -7456.0 |
| SDC1 | -7406.0 |
| OR10G2 | -7377.0 |
| XIRP2 | -7376.0 |
| OR4D6 | -7339.0 |
| SCN9A | -7326.0 |
| OR52M1 | -7318.0 |
| OR51B6 | -7304.0 |
| OR10G8 | -7289.0 |
| CNGA1 | -7270.0 |
| GNB3 | -7261.0 |
| GPC5 | -7260.0 |
| MYO7A | -7248.0 |
| OR8U1 | -7220.0 |
| HSD17B1 | -7219.0 |
| CALHM1 | -7203.0 |
| OR5AS1 | -7182.0 |
| OR56B1 | -7154.0 |
| TMIE | -7134.0 |
| OR5M9 | -7107.0 |
| CHRNA10 | -7089.0 |
| OR56A4 | -7070.0 |
| MYO15A | -6935.0 |
| OR10A2 | -6878.0 |
| OR52E8 | -6873.0 |
| AKR1C3 | -6863.0 |
| OR13C9 | -6797.0 |
| OR5F1 | -6781.0 |
| CHRNA9 | -6767.0 |
| SPTAN1 | -6744.0 |
| OR2L2 | -6740.0 |
| OR2F1 | -6728.0 |
| CNGB1 | -6692.0 |
| OR1L1 | -6665.0 |
| OR6C3 | -6602.0 |
| PLS1 | -6597.0 |
| OR1S1 | -6531.0 |
| CACNA1D | -6509.0 |
| LRP1 | -6481.0 |
| OR5B3 | -6448.0 |
| PCDH15 | -6428.0 |
| CACNA2D2 | -6407.0 |
| OR5H2 | -6376.0 |
| OR51F2 | -6371.0 |
| OR2T12 | -6318.0 |
| OR51B5 | -6274.0 |
| OR13F1 | -6220.0 |
| OR6C75 | -6121.0 |
| OR9Q2 | -6049.0 |
| OR9Q1 | -5971.0 |
| OR14A16 | -5941.0 |
| TMC1 | -5922.0 |
| OTOP1 | -5908.0 |
| OTOG | -5888.0 |
| EPB41L1 | -5836.0 |
| EBF1 | -5762.0 |
| TAS2R38 | -5742.0 |
| OR1B1 | -5679.0 |
| OR9G1 | -5649.5 |
| OR9G9 | -5649.5 |
| OR56B4 | -5538.0 |
| CALHM3 | -5534.0 |
| OR2T1 | -5516.0 |
| OR52N2 | -5493.0 |
| OR8B8 | -5480.0 |
| USH1C | -5292.0 |
| EPS8L2 | -5284.0 |
| OR10H3 | -5269.0 |
| APOA1 | -5192.0 |
| OR6N1 | -5094.0 |
| OR10AD1 | -4999.0 |
| OR6T1 | -4960.0 |
| TTR | -4959.0 |
| OR1D2 | -4955.0 |
| OR6Q1 | -4896.0 |
| GNAT3 | -4821.0 |
| OR52B6 | -4786.0 |
| GRXCR2 | -4742.0 |
| GPC6 | -4579.0 |
| OR7G2 | -4577.0 |
| OR4D1 | -4542.0 |
| OR51I1 | -4522.0 |
| OR8J1 | -4496.0 |
| APOC3 | -4472.0 |
| TAS2R30 | -4449.0 |
| OR2T3 | -4438.0 |
| CABP2 | -4351.0 |
| TAS2R50 | -4345.0 |
| OR4D5 | -4321.0 |
| GRM4 | -4317.0 |
| CTBP2 | -4238.0 |
| OR11G2 | -4184.0 |
| OR8A1 | -4138.0 |
| PDE6G | -3993.0 |
| PNLIP | -3892.0 |
| OR2V2 | -3818.0 |
| RDH8 | -3815.0 |
| OR2W3 | -3806.0 |
| OR1J2 | -3761.0 |
| OR5D16 | -3758.0 |
| LRP12 | -3691.0 |
| SCN4B | -3634.0 |
| OR6A2 | -3595.0 |
| OR8G5 | -3550.0 |
| PDE6B | -3532.0 |
| APOA2 | -3516.0 |
| OR10S1 | -3488.0 |
| GNGT1 | -3424.0 |
| CLIC5 | -3396.0 |
| OR4D2 | -3351.0 |
| FNTA | -3311.0 |
| TAS2R1 | -3281.0 |
| RDH12 | -3278.0 |
| ANO2 | -3233.0 |
| CDH23 | -3229.0 |
| RBP1 | -3208.0 |
| OR5AC2 | -3196.0 |
| OR2L5 | -3193.0 |
| GRXCR1 | -3183.0 |
| PRKCA | -3175.0 |
| OR10Z1 | -3155.0 |
| GPC1 | -3133.0 |
| RPE65 | -3116.0 |
| OR2A14 | -3113.0 |
| SCN2A | -3040.0 |
| TAS1R1 | -3029.0 |
| OR52A5 | -2976.0 |
| OR10C1 | -2952.0 |
| OR5K3 | -2947.0 |
| SCN1B | -2932.0 |
| OR2B3 | -2921.0 |
| TAS2R46 | -2898.0 |
| OR4N2 | -2889.0 |
| PLB1 | -2858.0 |
| CAMKMT | -2812.0 |
| OTOF | -2806.0 |
| RDX | -2784.0 |
| RGS9 | -2762.0 |
| TRIOBP | -2761.0 |
| RDH11 | -2752.0 |
| OR8D4 | -2668.0 |
| OR5AK2 | -2638.0 |
| OR10X1 | -2583.0 |
| FNTB | -2547.0 |
| SLC26A5 | -2494.0 |
| OR5M3 | -2438.0 |
| OR4K1 | -2419.0 |
| OR8G1 | -2384.0 |
| OR52I2 | -2243.0 |
| GRM1 | -2242.0 |
| OR7C1 | -2150.0 |
| DNAJC5 | -1965.0 |
| GPC2 | -1956.0 |
| OR10A4 | -1936.0 |
| OR56A5 | -1856.0 |
| RETSAT | -1789.0 |
| OR8U3 | -1737.0 |
| EPB41L3 | -1732.0 |
| OR11L1 | -1681.0 |
| OR5A1 | -1668.0 |
| OR6C1 | -1650.0 |
| CALM1 | -1622.0 |
| TAS1R2 | -1566.0 |
| KCNMA1 | -1532.0 |
| OR5M1 | -1527.0 |
| OR4A16 | -1515.0 |
| PRKCQ | -1471.0 |
| OR4K14 | -1436.0 |
| OR6B3 | -1262.0 |
| OR6M1 | -1239.0 |
| OR52A1 | -1194.0 |
| ATP2B1 | -1189.0 |
| PJVK | -1157.0 |
| RTP2 | -1143.0 |
| OR2C1 | -1126.0 |
| METAP1 | -651.0 |
| SCNN1D | -614.0 |
| KCNN2 | -594.0 |
| ATP2B2 | -528.0 |
| CYP4V2 | -418.0 |
| OR52W1 | -410.0 |
| OR8K1 | -396.0 |
| NMT1 | -381.0 |
| OR2H1 | -335.0 |
| OR2V1 | -287.0 |
| CACNB2 | -251.0 |
| APOB | -225.0 |
| OR56A3 | -180.0 |
| OR2K2 | -176.0 |
| SLC17A8 | -162.0 |
| OR2Z1 | -65.0 |
| TRPM4 | 21.0 |
| GUCA1B | 162.0 |
| OR8B2 | 192.0 |
| OR7A17 | 298.0 |
| OR1F1 | 353.0 |
| OR1N2 | 355.0 |
| OR10G3 | 378.0 |
| OR6N2 | 453.0 |
| OR8K3 | 618.0 |
| BSN | 662.0 |
| OR3A3 | 709.0 |
| OR14J1 | 846.0 |
| LRP2 | 860.0 |
| OR6K3 | 926.0 |
| OR8H1 | 960.0 |
| TAS1R3 | 971.0 |
| CAPZB | 1024.0 |
| OR51B2 | 1031.0 |
| GRK4 | 1038.0 |
| DHRS3 | 1133.0 |
| OR10H2 | 1198.0 |
| STX1A | 1212.0 |
| OR12D3 | 1348.0 |
| WHRN | 1507.0 |
| GUCY2D | 1511.0 |
| OR9A4 | 1516.0 |
| OR10G4 | 1583.0 |
| ESPNL | 1638.0 |
| OR13C8 | 1741.0 |
| OR51V1 | 1756.0 |
| OR2D3 | 1827.0 |
| GUCA1A | 1901.0 |
| OR52B2 | 1915.0 |
| OR1A2 | 2044.0 |
| OR51A2 | 2136.0 |
| OR10Q1 | 2166.0 |
| KCNMB1 | 2329.0 |
| ABCA4 | 2406.0 |
| TWF2 | 2428.0 |
| BCO2 | 2536.0 |
| OR6X1 | 2590.0 |
| OR6C70 | 2634.0 |
| PDE6A | 2660.0 |
| SCNN1A | 2688.0 |
| SCNN1G | 2713.0 |
| OR2W1 | 2754.0 |
| OR10W1 | 2812.0 |
| RBP4 | 2834.0 |
| EZR | 2889.0 |
| MYO3B | 2986.0 |
| SPTBN1 | 2995.0 |
| OR51B4 | 2998.0 |
| OR6C68 | 3042.0 |
| TRPM5 | 3145.0 |
| RDH10 | 3178.0 |
| SDR9C7 | 3191.0 |
| RDH5 | 3222.0 |
| OR7C2 | 3230.0 |
| KCNQ4 | 3231.0 |
| OR5K1 | 3254.0 |
| OR10G9 | 3293.0 |
| CIB2 | 3304.0 |
| KCNJ2 | 3322.0 |
| TAS2R7 | 3323.0 |
| USH1G | 3403.0 |
| OR2T33 | 3637.0 |
| OR10AG1 | 3681.0 |
| OR1E2 | 3752.0 |
| OR4K13 | 3771.0 |
| SLC24A1 | 3790.0 |
| AGRN | 3792.0 |
| TAS2R4 | 3808.0 |
| OR2B11 | 3813.0 |
| OR6K6 | 3833.0 |
| OR7A10 | 3856.0 |
| OR8S1 | 3869.0 |
| LPL | 3873.0 |
| CAPZA2 | 3961.0 |
| LHFPL5 | 4010.0 |
| OR9G4 | 4147.0 |
| GNAL | 4308.0 |
| OR14I1 | 4334.0 |
| CABP1 | 4340.0 |
| OR3A2 | 4394.0 |
| GSN | 4432.0 |
| SCNN1B | 4468.0 |
| SAG | 4534.0 |
| TWF1 | 4550.0 |
| SCN2B | 4551.0 |
| OR4C3 | 4566.0 |
| RIPOR2 | 4597.0 |
| LHX2 | 4613.0 |
| NAPEPLD | 4678.0 |
| SNAP25 | 4681.0 |
| OR4X2 | 4693.0 |
| GRK7 | 4780.0 |
| OR11H4 | 4791.0 |
| VAMP2 | 4802.0 |
| MYH9 | 4847.0 |
| OR10H5 | 4852.0 |
| OR2F2 | 4932.0 |
| PLCB2 | 5165.0 |
| CAPZA1 | 5374.0 |
| MYO1C | 5390.0 |
| APOA4 | 5535.0 |
| OR10A7 | 5665.0 |
| OR2B2 | 5706.0 |
| LRP10 | 5726.0 |
| OR1J4 | 5763.0 |
| SDC3 | 5772.0 |
| OR4A5 | 5820.0 |
| OR4B1 | 6037.0 |
| OR4C45 | 6093.0 |
| OR9I1 | 6129.0 |
| OR2T4 | 6191.0 |
| RCVRN | 6192.0 |
| GNB5 | 6369.0 |
| OR1A1 | 6370.0 |
| STRC | 6399.0 |
| OR4K17 | 6511.0 |
| DHRS9 | 6619.0 |
| OR2G2 | 6652.0 |
| LRAT | 6832.0 |
| OR1G1 | 6884.0 |
| OR10T2 | 6946.0 |
| OR2AG2 | 7021.0 |
| OR1L8 | 7066.0 |
| GNAT1 | 7102.0 |
| OR51G1 | 7233.0 |
| OR4S1 | 7263.0 |
| OR5H6 | 7316.0 |
| NMT2 | 7350.0 |
| OR5T1 | 7464.0 |
| ESPN | 7477.0 |
| GNB1 | 7509.0 |
| RGS9BP | 7623.0 |
| OR4A15 | 7657.0 |
| OR4L1 | 7886.0 |
| TAS2R3 | 7891.0 |
| RAB3A | 7925.0 |
| OR6B1 | 8134.0 |
| OR2J2 | 8148.0 |
| OR2AP1 | 8289.0 |
| OR1I1 | 8352.0 |
| OR5W2 | 8354.0 |
| OR4C6 | 8379.0 |
| OR5D18 | 8385.0 |
| OR2D2 | 8494.0 |
| OR2M5 | 8523.0 |
| GRK1 | 8583.0 |
| OR11H6 | 8600.0 |
| AKR1C4 | 8664.0 |
| RLBP1 | 8710.0 |
| LRRC52 | 8761.0 |
| OR10J1 | 8773.0 |
| OR13C3 | 8825.0 |
| OR4C16 | 8867.0 |
| REEP1 | 8878.0 |
| LDB1 | 8879.0 |
| OR1K1 | 8899.0 |
| TPRN | 8961.0 |
| OR52E4 | 9057.0 |
| APOM | 9073.0 |
| OR6B2 | 9080.0 |
| OR6C65 | 9179.0 |
| OR2T11 | 9244.0 |
| OR1L6 | 9273.0 |
| OR4K5 | 9299.0 |
| OR2AE1 | 9347.0 |
| OR9A2 | 9358.0 |
| METAP2 | 9375.0 |
| OR1S2 | 9383.0 |
| OR51E2 | 9398.0 |
| OR5M10 | 9399.0 |
| OR6C74 | 9425.0 |
| RDH16 | 9470.0 |
| OR13A1 | 9486.0 |
| OR2T8 | 9527.0 |
| OR52K1 | 9570.0 |
| OR13C2 | 9625.0 |
| ACTB | 9643.0 |
| FSCN2 | 9646.0 |
| OR2AG1 | 9733.0 |
| OR52L1 | 9742.0 |
| OR52K2 | 9750.0 |
| OR1M1 | 9752.0 |
| OR2H2 | 9770.0 |
| OR4F15 | 9800.0 |
| OR7G3 | 9819.0 |
| OR3A1 | 9879.0 |
| OR7E24 | 9975.0 |
| ACTG1 | 9978.0 |
| OR5B17 | 10000.0 |
| OR4K15 | 10185.0 |
| OR4F6 | 10203.0 |
| TAS2R31 | 10217.0 |
| OR10V1 | 10219.0 |
| OR13C4 | 10245.0 |
| OR7D4 | 10288.0 |
| OR5D13 | 10360.0 |
| OR10P1 | 10404.0 |
| OR1J1 | 10445.0 |
| OR2S2 | 10467.0 |
| OR4N5 | 10475.0 |
| APOE | 10494.0 |
| OR5AU1 | 10534.0 |
| OR51Q1 | 10548.0 |
| GNG13 | 10553.0 |
| OR1E1 | 10619.0 |
| OR4K2 | 10626.0 |
| OR4D9 | 10688.0 |
| OR51G2 | 10708.0 |
| OR9K2 | 10730.0 |
| OR4X1 | 10757.0 |
| OR1L4 | 10761.0 |
| OR6C4 | 10831.0 |
| OR4A47 | 10848.0 |
| OR52I1 | 10877.0 |
| OR5H15 | 10908.0 |
| OR2M7 | 10981.0 |
| OR4C46 | 11021.0 |
| OR4C12 | 11031.0 |
REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION
| 1161 | |
|---|---|
| set | REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION |
| setSize | 1336 |
| pANOVA | 2.71e-08 |
| s.dist | 0.0906 |
| p.adjustANOVA | 7.41e-06 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CGB5 | 11144 |
| CGB8 | 11143 |
| ZNF320 | 11118 |
| ELOB | 10991 |
| THOC3 | 10946 |
| SMARCC2 | 10923 |
| ZNF716 | 10878 |
| ZNF658 | 10842 |
| ZNF732 | 10832 |
| E2F1 | 10764 |
| H4C8 | 10752 |
| TGIF2 | 10679 |
| TAF7 | 10601 |
| SRSF6 | 10598 |
| GADD45A | 10546 |
| NR0B2 | 10540 |
| MED6 | 10519 |
| CDK4 | 10506 |
| APOE | 10494 |
| ZNF473 | 10420 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CGB5 | 11144.0 |
| CGB8 | 11143.0 |
| ZNF320 | 11118.0 |
| ELOB | 10991.0 |
| THOC3 | 10946.0 |
| SMARCC2 | 10923.0 |
| ZNF716 | 10878.0 |
| ZNF658 | 10842.0 |
| ZNF732 | 10832.0 |
| E2F1 | 10764.0 |
| H4C8 | 10752.0 |
| TGIF2 | 10679.0 |
| TAF7 | 10601.0 |
| SRSF6 | 10598.0 |
| GADD45A | 10546.0 |
| NR0B2 | 10540.0 |
| MED6 | 10519.0 |
| CDK4 | 10506.0 |
| APOE | 10494.0 |
| ZNF473 | 10420.0 |
| POLR2K | 10402.0 |
| PTPN11 | 10353.0 |
| PSMD12 | 10325.0 |
| CDKN2B | 10314.0 |
| NR4A2 | 10309.0 |
| ZNF597 | 10304.0 |
| ZNF354C | 10266.0 |
| NKX2-5 | 10264.0 |
| PRKAG1 | 10260.0 |
| NPPA | 10240.0 |
| CNOT8 | 10218.0 |
| AGO1 | 10212.0 |
| ZNF713 | 10187.0 |
| SUZ12 | 10134.0 |
| MED25 | 10131.0 |
| THOC6 | 10125.0 |
| ZNF354A | 10090.0 |
| MIR137 | 10069.0 |
| COX11 | 10031.0 |
| TAF6 | 10014.0 |
| ZNF155 | 10012.0 |
| ZNF224 | 9995.0 |
| TEAD2 | 9990.0 |
| PSMC6 | 9977.0 |
| STUB1 | 9936.0 |
| ZNF175 | 9935.0 |
| JUNB | 9929.0 |
| BTG1 | 9918.0 |
| TP53RK | 9916.0 |
| MED30 | 9899.0 |
| H2AJ | 9870.0 |
| PSMB3 | 9858.0 |
| ZNF70 | 9847.0 |
| RGCC | 9838.0 |
| GATA2 | 9817.0 |
| CBFB | 9784.0 |
| CSTF2T | 9749.0 |
| ZNF662 | 9747.0 |
| MED1 | 9736.0 |
| ELL3 | 9725.0 |
| PIP4P1 | 9706.0 |
| ZNF689 | 9679.0 |
| CYCS | 9670.0 |
| PERP | 9660.0 |
| GPI | 9649.0 |
| JUN | 9609.0 |
| ZNF554 | 9600.0 |
| RBM8A | 9578.0 |
| ZNF735 | 9577.0 |
| BID | 9555.0 |
| ZNF394 | 9541.0 |
| RNU11 | 9537.0 |
| NR1I3 | 9517.0 |
| DDIT4 | 9511.0 |
| UBC | 9476.0 |
| ZNF442 | 9453.0 |
| MIR24-2 | 9434.0 |
| DEK | 9433.0 |
| SNAPC5 | 9426.0 |
| ELOC | 9413.0 |
| KIT | 9372.0 |
| ZNF256 | 9356.0 |
| ZNF77 | 9340.0 |
| ZNF383 | 9338.0 |
| ZNF701 | 9320.0 |
| ZNF567 | 9315.0 |
| RBX1 | 9293.0 |
| LAMTOR4 | 9268.0 |
| ZNF154 | 9266.0 |
| ZNF418 | 9264.0 |
| ZNF671 | 9258.0 |
| ZNF678 | 9250.0 |
| RAD1 | 9237.0 |
| KAT5 | 9221.0 |
| IL6 | 9220.0 |
| LRPPRC | 9205.0 |
| RABGGTB | 9195.0 |
| RBM14 | 9172.0 |
| SESN2 | 9164.0 |
| NPAS4 | 9162.0 |
| MED10 | 9083.0 |
| TRPC3 | 9056.0 |
| CNOT11 | 9045.0 |
| H3C10 | 9015.0 |
| RARA | 9010.0 |
| TXN | 8969.0 |
| H3C11 | 8963.0 |
| ZNF160 | 8920.0 |
| PCGF2 | 8893.0 |
| ZNF211 | 8892.0 |
| H4C12 | 8883.0 |
| LDB1 | 8879.0 |
| CPSF6 | 8868.0 |
| ZNF195 | 8856.0 |
| KAT2B | 8850.0 |
| ZKSCAN8 | 8829.0 |
| PRDM7 | 8823.0 |
| AURKB | 8795.0 |
| SUPT6H | 8783.0 |
| ZNF460 | 8779.0 |
| PIP4K2A | 8762.0 |
| ZNF692 | 8757.0 |
| EAF2 | 8754.0 |
| TAF15 | 8749.0 |
| MAPK14 | 8739.0 |
| ZNF189 | 8737.0 |
| CSNK2B | 8721.0 |
| ZNF619 | 8697.0 |
| H4C2 | 8690.0 |
| PSME2 | 8685.0 |
| H3-3A | 8639.0 |
| BARD1 | 8638.0 |
| ZNF350 | 8618.0 |
| H2BC13 | 8609.0 |
| ZKSCAN5 | 8594.0 |
| ITGA2B | 8571.0 |
| RYBP | 8552.0 |
| ZNF324 | 8531.0 |
| LAMTOR2 | 8526.0 |
| COX4I1 | 8524.0 |
| NKX3-2 | 8516.0 |
| ZNF446 | 8501.0 |
| MDM4 | 8496.0 |
| SRSF1 | 8481.0 |
| DDX39B | 8477.0 |
| ZNF710 | 8462.0 |
| HDAC11 | 8461.0 |
| CDKN1B | 8453.0 |
| TGFB1 | 8436.0 |
| CCNH | 8435.0 |
| LMO2 | 8413.0 |
| CTSV | 8398.0 |
| ZNF564 | 8389.0 |
| H2BC1 | 8383.0 |
| ZNF785 | 8378.0 |
| TAF13 | 8377.0 |
| ZNF3 | 8376.0 |
| PMS2 | 8329.0 |
| ZNF675 | 8327.0 |
| DNA2 | 8298.0 |
| ZNF566 | 8292.0 |
| GATAD2B | 8270.0 |
| TAF10 | 8254.0 |
| PAF1 | 8253.0 |
| ZNF543 | 8249.0 |
| PRKAG3 | 8225.0 |
| ZNF426 | 8222.0 |
| ZNF302 | 8214.0 |
| THRA | 8201.0 |
| SPI1 | 8199.0 |
| PARP1 | 8191.0 |
| ZNF613 | 8186.0 |
| PSMB4 | 8180.0 |
| ZNF334 | 8168.0 |
| INTS7 | 8132.0 |
| SMAD4 | 8113.0 |
| TP53 | 8108.0 |
| ZNF234 | 8104.0 |
| MIR132 | 8101.0 |
| ZKSCAN4 | 8095.0 |
| CBX5 | 8092.0 |
| ZNF625 | 8089.0 |
| SYT10 | 8062.0 |
| H3C12 | 8052.0 |
| ALYREF | 8040.0 |
| BRD2 | 8023.0 |
| TACO1 | 7999.0 |
| ZNF143 | 7982.0 |
| CNOT6 | 7981.0 |
| ZC3H11A | 7947.0 |
| POLR2I | 7943.0 |
| ZNF799 | 7927.0 |
| RFFL | 7911.0 |
| LSM11 | 7904.0 |
| PSMD13 | 7901.0 |
| PRR5 | 7860.0 |
| TXNIP | 7855.0 |
| ZNF492 | 7833.0 |
| NR1D1 | 7831.0 |
| RBBP8 | 7822.0 |
| TCF7 | 7815.0 |
| H2AZ2 | 7814.0 |
| JAG1 | 7806.0 |
| COX16 | 7805.0 |
| ZNF770 | 7771.0 |
| H2AC7 | 7754.5 |
| H2BC7 | 7754.5 |
| RNF111 | 7746.0 |
| VENTX | 7728.0 |
| SNW1 | 7713.0 |
| ZNF706 | 7711.0 |
| PSME4 | 7705.0 |
| CPSF2 | 7686.0 |
| RPRD2 | 7676.0 |
| UBB | 7674.0 |
| ARNT | 7661.0 |
| PSMB2 | 7641.0 |
| MAML1 | 7625.0 |
| ZFP37 | 7604.0 |
| TRIM63 | 7588.0 |
| SMARCE1 | 7576.0 |
| ZNF432 | 7559.0 |
| ZFP28 | 7548.0 |
| ERCC2 | 7510.0 |
| VEGFA | 7485.0 |
| TRIM28 | 7470.0 |
| ZNF14 | 7453.0 |
| RNU12 | 7438.0 |
| KMT5A | 7432.0 |
| CCNB1 | 7396.0 |
| INTS12 | 7386.0 |
| INTS9 | 7373.0 |
| TAF1L | 7369.0 |
| PSMB11 | 7359.0 |
| HNF4A | 7358.0 |
| ZNF771 | 7344.0 |
| PTPN1 | 7323.0 |
| PRELID1 | 7311.0 |
| CDKN2A | 7282.0 |
| CASP10 | 7274.0 |
| MED31 | 7267.0 |
| H4C16 | 7260.0 |
| SIN3A | 7192.0 |
| PSMA6 | 7190.0 |
| TPX2 | 7183.0 |
| BIRC5 | 7158.0 |
| ZNF510 | 7155.0 |
| RPS27A | 7120.0 |
| BCL2L14 | 7103.0 |
| GTF2H1 | 7100.0 |
| CTLA4 | 7043.0 |
| ZNF443 | 7029.0 |
| CDC25C | 7020.0 |
| PSMA1 | 7018.0 |
| GATAD2A | 7005.0 |
| CCND3 | 6976.0 |
| NR2C2 | 6972.0 |
| ANAPC11 | 6955.0 |
| CDK2 | 6939.0 |
| ZNF548 | 6936.0 |
| COX7C | 6918.0 |
| PRMT6 | 6910.0 |
| CHEK1 | 6909.0 |
| KAT6A | 6894.0 |
| RBBP5 | 6882.0 |
| TTC5 | 6881.0 |
| SMARCA2 | 6869.0 |
| NPM1 | 6858.0 |
| PBRM1 | 6857.0 |
| RBBP4 | 6844.0 |
| ZFP90 | 6806.0 |
| SUPT16H | 6796.0 |
| ARID1A | 6758.0 |
| DDIT3 | 6748.0 |
| ITGA5 | 6740.0 |
| ZNF416 | 6739.0 |
| ZNF300 | 6725.0 |
| MIR27A | 6701.0 |
| CCNG1 | 6695.0 |
| LBR | 6693.0 |
| MAF | 6687.0 |
| ELF1 | 6675.0 |
| PSMD3 | 6672.0 |
| MDC1 | 6671.0 |
| LEO1 | 6667.0 |
| SKIL | 6657.0 |
| RHNO1 | 6649.0 |
| GAD1 | 6647.0 |
| RAD9A | 6635.0 |
| NFE2 | 6632.0 |
| H2AC8 | 6630.0 |
| ZNF626 | 6621.0 |
| ZNF227 | 6618.0 |
| CASP6 | 6582.0 |
| CDC40 | 6559.0 |
| ZFP30 | 6530.0 |
| COX6C | 6519.0 |
| ZNF333 | 6504.0 |
| RXRB | 6459.0 |
| U2AF1L4 | 6453.0 |
| EIF4A3 | 6420.0 |
| ZNF33A | 6365.0 |
| NR3C1 | 6322.0 |
| PCF11 | 6318.0 |
| CHD4 | 6316.0 |
| ZNF141 | 6243.0 |
| HDAC10 | 6236.0 |
| BCL6 | 6221.0 |
| CBX3 | 6210.0 |
| CDK12 | 6198.0 |
| MOV10 | 6170.0 |
| H3-3B | 6110.0 |
| H2BC8 | 6087.0 |
| RRAGC | 6080.0 |
| ZNF226 | 6079.0 |
| TCEA1 | 6057.0 |
| TGIF1 | 6054.0 |
| CREB1 | 6047.0 |
| ZNF621 | 6027.0 |
| TRIAP1 | 6007.0 |
| GTF2H3 | 5990.0 |
| AURKA | 5946.0 |
| H4C3 | 5935.0 |
| YEATS4 | 5923.0 |
| ICE1 | 5905.0 |
| YWHAB | 5879.0 |
| ZNF551 | 5874.0 |
| ANAPC10 | 5865.0 |
| H4C1 | 5864.0 |
| PMAIP1 | 5853.0 |
| PVALB | 5851.0 |
| PPP1R13L | 5846.0 |
| ZC3H8 | 5845.0 |
| MLH1 | 5844.0 |
| PRDX1 | 5840.0 |
| SMARCD1 | 5835.0 |
| TIGAR | 5827.0 |
| ZNF470 | 5783.0 |
| GAMT | 5779.0 |
| RB1 | 5745.0 |
| CSTF3 | 5738.0 |
| KCTD6 | 5723.0 |
| PSMC1 | 5715.0 |
| SNAPC1 | 5713.0 |
| NCBP1 | 5705.0 |
| TWIST2 | 5695.0 |
| ZNF500 | 5691.0 |
| NFYC | 5655.0 |
| ZNF738 | 5653.0 |
| RPA1 | 5651.0 |
| ZNF208 | 5645.0 |
| PSMD2 | 5624.0 |
| MRE11 | 5620.0 |
| H3C1 | 5598.0 |
| ZNF737 | 5592.0 |
| ZNF624 | 5589.0 |
| ZNF138 | 5524.0 |
| NOP2 | 5509.0 |
| ZNF700 | 5507.0 |
| PABPN1 | 5490.0 |
| AGO4 | 5459.0 |
| ZNF37A | 5452.0 |
| ZNF552 | 5422.0 |
| CSTF1 | 5411.0 |
| SMARCD3 | 5379.0 |
| SETD1B | 5369.0 |
| ZNF839 | 5365.0 |
| PSMA5 | 5362.0 |
| SRSF3 | 5357.0 |
| ANAPC2 | 5346.0 |
| ZNF563 | 5338.0 |
| HDAC2 | 5322.0 |
| PHC1 | 5291.0 |
| NR4A3 | 5266.0 |
| ZNF546 | 5248.0 |
| PSMA4 | 5246.0 |
| SNRPF | 5221.0 |
| PSMC5 | 5193.0 |
| LMO1 | 5192.0 |
| CDK8 | 5175.0 |
| SESN3 | 5150.0 |
| H2BC5 | 5130.0 |
| RBL2 | 5110.0 |
| SRSF7 | 5105.0 |
| KMT2A | 5079.0 |
| CDKN1A | 5054.0 |
| ZNF233 | 5050.0 |
| TAF11 | 5030.0 |
| ZNF614 | 5022.0 |
| CCNT2 | 5011.0 |
| TP73 | 5000.0 |
| DAXX | 4994.0 |
| SMAD7 | 4978.0 |
| SKIC8 | 4957.0 |
| H4C6 | 4952.0 |
| POLDIP3 | 4943.0 |
| SLC2A3 | 4924.0 |
| NDUFA4 | 4915.0 |
| ZNF43 | 4879.0 |
| ZNF684 | 4872.0 |
| E2F8 | 4845.0 |
| PCNA | 4821.0 |
| KRAS | 4814.0 |
| ZNF587 | 4734.0 |
| H3C4 | 4718.0 |
| ITGA4 | 4701.0 |
| CSNK2A1 | 4697.0 |
| PINK1 | 4683.0 |
| CEBPB | 4682.0 |
| BMI1 | 4673.0 |
| ANAPC5 | 4671.0 |
| H2BC3 | 4658.0 |
| YWHAZ | 4655.0 |
| SOCS4 | 4646.0 |
| H4C13 | 4630.0 |
| CNOT1 | 4620.0 |
| ZNF429 | 4614.0 |
| BRIP1 | 4606.0 |
| ATM | 4600.0 |
| BMP2 | 4573.0 |
| SSRP1 | 4571.0 |
| ZNF641 | 4567.0 |
| ZNF699 | 4565.0 |
| H4C11 | 4553.0 |
| INTS14 | 4535.0 |
| RNPS1 | 4528.0 |
| NELFE | 4505.0 |
| TFAP2B | 4489.0 |
| CRH | 4485.0 |
| ZNF747 | 4452.0 |
| ZKSCAN3 | 4442.0 |
| PPM1A | 4430.0 |
| SESN1 | 4424.0 |
| NR5A1 | 4418.0 |
| ZNF562 | 4371.0 |
| CITED4 | 4332.0 |
| PRELID3A | 4322.0 |
| SLU7 | 4319.0 |
| PSMF1 | 4311.0 |
| ZNF746 | 4296.0 |
| CCND2 | 4278.0 |
| UBE2I | 4265.0 |
| CCNG2 | 4258.0 |
| CTDP1 | 4247.0 |
| BLM | 4237.0 |
| SMARCD2 | 4230.0 |
| PSMD1 | 4227.0 |
| ZNF557 | 4225.0 |
| TNRC6B | 4201.0 |
| ZNF776 | 4200.0 |
| NUAK1 | 4190.0 |
| ARID3A | 4176.0 |
| PSME3 | 4172.0 |
| SARNP | 4167.0 |
| ZNF225 | 4163.0 |
| MBD3 | 4139.0 |
| EAF1 | 4134.0 |
| BRD7 | 4133.0 |
| CSNK2A2 | 4122.0 |
| GATA3 | 4111.0 |
| PSMC2 | 4088.0 |
| CASC3 | 4044.0 |
| E2F5 | 4024.0 |
| ZNF343 | 4016.0 |
| FASLG | 3973.0 |
| ZKSCAN7 | 3957.0 |
| H2BC10 | 3947.0 |
| NPY | 3933.0 |
| PSMA8 | 3923.0 |
| PPM1D | 3918.0 |
| POLR2A | 3916.0 |
| TAL1 | 3910.0 |
| ZNF431 | 3906.0 |
| PSMA7 | 3903.0 |
| ZNF607 | 3884.0 |
| PSME1 | 3866.0 |
| ZNF791 | 3864.0 |
| PSMA3 | 3850.0 |
| ZNF235 | 3839.0 |
| GRIA2 | 3830.0 |
| LAMTOR5 | 3821.0 |
| ZNF606 | 3801.0 |
| TBX5 | 3796.0 |
| SRSF2 | 3788.0 |
| COX6B1 | 3786.0 |
| H4C4 | 3785.0 |
| NELFCD | 3781.0 |
| CBX2 | 3753.0 |
| GPAM | 3748.0 |
| BDNF | 3731.0 |
| TWIST1 | 3725.0 |
| MED26 | 3708.0 |
| ZNF749 | 3686.0 |
| ZNF23 | 3638.0 |
| PPP1R13B | 3624.0 |
| MED15 | 3621.0 |
| SYMPK | 3608.0 |
| ATF2 | 3606.0 |
| MOBP | 3602.0 |
| EXO1 | 3595.0 |
| CCNA1 | 3593.0 |
| PRDX5 | 3588.0 |
| PIP4K2B | 3579.0 |
| GTF2E1 | 3557.0 |
| PRKCB | 3548.0 |
| SKP1 | 3534.0 |
| DDX39A | 3522.0 |
| PRKACA | 3519.0 |
| TCF7L1 | 3516.0 |
| G6PC1 | 3487.0 |
| PSMB9 | 3459.0 |
| SP7 | 3428.0 |
| SNRPG | 3425.0 |
| SNAPC4 | 3423.0 |
| CHEK2 | 3413.0 |
| PPARA | 3412.0 |
| PPP2R5C | 3398.0 |
| MSH2 | 3394.0 |
| RBPJ | 3392.0 |
| HUS1 | 3387.0 |
| BTG2 | 3356.0 |
| TFDP2 | 3339.0 |
| ERBB2 | 3331.0 |
| ZNF696 | 3295.0 |
| NRBF2 | 3283.0 |
| ZNF75A | 3278.0 |
| H2BC17 | 3276.0 |
| ZNF101 | 3261.0 |
| MYB | 3241.0 |
| ELL2 | 3218.0 |
| TAF5 | 3203.0 |
| CCNE2 | 3190.0 |
| POLR2E | 3177.0 |
| PRDM1 | 3158.0 |
| ZNF468 | 3154.0 |
| RFC2 | 3136.0 |
| ZNF793 | 3067.0 |
| ZNF660 | 3066.0 |
| CDC27 | 3049.0 |
| PRMT5 | 3035.0 |
| ZNF221 | 3027.0 |
| H3C6 | 3009.0 |
| PSMC4 | 3004.0 |
| UBE2D3 | 2976.0 |
| PSMC3 | 2960.0 |
| H2AC6 | 2946.0 |
| GTF2F2 | 2945.0 |
| NR1I2 | 2937.0 |
| GTF2A1 | 2934.0 |
| CPSF7 | 2925.0 |
| ZNF267 | 2903.0 |
| NABP2 | 2875.0 |
| INTS5 | 2870.0 |
| RRAGD | 2813.0 |
| TP53INP1 | 2810.0 |
| CHTOP | 2800.0 |
| NR2E1 | 2781.0 |
| EHMT1 | 2779.0 |
| SST | 2763.0 |
| GLS | 2758.0 |
| SRF | 2755.0 |
| TFAP2E | 2752.0 |
| KMT2D | 2700.0 |
| H3C8 | 2699.0 |
| YWHAH | 2697.0 |
| ZNF782 | 2684.0 |
| ZNF274 | 2661.0 |
| GLS2 | 2636.0 |
| COL1A2 | 2619.0 |
| ZNF99 | 2594.0 |
| POU4F2 | 2584.0 |
| CBX6 | 2581.0 |
| IGFBP3 | 2553.0 |
| ZNF560 | 2550.0 |
| SKI | 2546.0 |
| SEM1 | 2517.0 |
| ZNF337 | 2505.0 |
| ERCC3 | 2481.0 |
| USP2 | 2480.0 |
| POMC | 2478.0 |
| ZNF223 | 2469.0 |
| GRIN2B | 2438.0 |
| PGR | 2421.0 |
| PITX2 | 2411.0 |
| YBX1 | 2391.0 |
| ZNF10 | 2380.0 |
| H2AC4 | 2379.0 |
| MEF2C | 2335.0 |
| ZNF615 | 2326.0 |
| ZNF544 | 2311.0 |
| ITCH | 2310.0 |
| CDC26 | 2306.0 |
| ZNF28 | 2297.0 |
| RARG | 2294.0 |
| PPP2CA | 2292.0 |
| ZNF528 | 2282.0 |
| PCGF5 | 2267.0 |
| PRMT1 | 2256.0 |
| FOS | 2247.0 |
| ZNF282 | 2239.0 |
| THOC7 | 2236.0 |
| CTR9 | 2229.0 |
| PPARG | 2203.0 |
| RTF1 | 2194.0 |
| COX20 | 2175.0 |
| ZNF729 | 2168.0 |
| MAPKAPK5 | 2167.0 |
| INTS6 | 2157.0 |
| ZNF517 | 2129.0 |
| ZNF540 | 2113.0 |
| SMURF1 | 2112.0 |
| NUDT21 | 2107.0 |
| HTT | 2070.0 |
| RSPO3 | 2060.0 |
| ZNF248 | 2037.0 |
| POLR2D | 2025.0 |
| ZNF596 | 2015.0 |
| ZNF184 | 2014.0 |
| CTSK | 2011.0 |
| INS | 2006.0 |
| PCK1 | 1998.0 |
| THBS1 | 1992.0 |
| ZNF420 | 1965.0 |
| RPRD1B | 1957.0 |
| ANAPC15 | 1950.0 |
| ZNF697 | 1936.0 |
| CDC23 | 1927.0 |
| GSR | 1919.0 |
| ZNF565 | 1914.0 |
| DGCR8 | 1910.0 |
| CENPJ | 1883.0 |
| BBC3 | 1846.0 |
| ZNF664 | 1842.0 |
| TXNRD1 | 1835.0 |
| ZNF616 | 1804.0 |
| CPSF1 | 1778.0 |
| NR2F1 | 1767.0 |
| BAX | 1761.0 |
| MEN1 | 1758.0 |
| HDAC5 | 1757.0 |
| LAMTOR1 | 1723.0 |
| HDAC3 | 1718.0 |
| IGFBP1 | 1703.0 |
| SRSF4 | 1674.0 |
| ZNF611 | 1664.0 |
| SNAPC2 | 1619.0 |
| GAD2 | 1601.0 |
| ASH2L | 1593.0 |
| RING1 | 1572.0 |
| RNGTT | 1562.0 |
| NRBP1 | 1533.0 |
| SRRT | 1488.0 |
| CDC7 | 1479.0 |
| ZNF222 | 1473.0 |
| ZNF354B | 1469.0 |
| MYBL2 | 1460.0 |
| H3C2 | 1438.0 |
| ZNF860 | 1436.0 |
| DLX5 | 1427.0 |
| CBX8 | 1425.0 |
| ITGAL | 1423.0 |
| ZNF436 | 1421.0 |
| TAF4B | 1414.0 |
| SURF1 | 1393.0 |
| CCNC | 1375.0 |
| GTF2H4 | 1369.0 |
| CNOT4 | 1341.0 |
| H2BC11 | 1338.0 |
| EHMT2 | 1321.0 |
| CNOT9 | 1314.0 |
| POU2F1 | 1312.0 |
| ZNF264 | 1304.0 |
| SNRPD3 | 1285.0 |
| DLL1 | 1276.0 |
| POU2F2 | 1275.0 |
| TAF9 | 1265.0 |
| COX6A1 | 1217.0 |
| L3MBTL2 | 1199.0 |
| KMT2E | 1173.0 |
| BRCA1 | 1120.0 |
| RPA2 | 1117.0 |
| STAT1 | 1103.0 |
| ZNF34 | 1095.0 |
| SNRPE | 1082.0 |
| CCNK | 1079.0 |
| MEAF6 | 1056.0 |
| GPS2 | 1041.0 |
| ZNF655 | 1018.0 |
| PML | 1014.0 |
| ATXN3 | 963.0 |
| ZFP69B | 953.0 |
| FYTTD1 | 934.0 |
| WDR33 | 931.0 |
| ZNF253 | 914.0 |
| CCNT1 | 863.0 |
| TAF8 | 830.0 |
| RFC4 | 824.0 |
| FANCD2 | 822.0 |
| ZNF440 | 811.0 |
| SMARCC1 | 773.0 |
| CDC16 | 754.0 |
| YWHAE | 744.0 |
| RAD51D | 730.0 |
| DDB2 | 719.0 |
| BLK | 690.0 |
| KLF4 | 683.0 |
| ELOA | 667.0 |
| MSX2 | 656.0 |
| PSMD11 | 620.0 |
| PIN1 | 606.0 |
| ZKSCAN1 | 599.0 |
| MED8 | 521.0 |
| H2AX | 499.0 |
| DHX38 | 488.0 |
| PCBP4 | 475.0 |
| PSMB8 | 447.0 |
| NR5A2 | 402.0 |
| SSU72 | 387.0 |
| PRKAB2 | 365.0 |
| RPRD1A | 364.0 |
| NFYA | 361.0 |
| HDAC1 | 346.0 |
| YWHAQ | 336.0 |
| SRSF9 | 313.0 |
| SMARCA4 | 311.0 |
| ING2 | 309.0 |
| ZNF324B | 287.0 |
| NAMPT | 284.0 |
| RAD17 | 283.0 |
| KDM5B | 280.0 |
| CAV1 | 267.0 |
| TOP3A | 244.0 |
| H2BC15 | 240.0 |
| ESR1 | 230.0 |
| MDM2 | 219.0 |
| ZNF124 | 217.0 |
| ZNF92 | 207.0 |
| CBX4 | 205.0 |
| GRIN2A | 181.0 |
| ZNF230 | 166.0 |
| BCL2L11 | 135.0 |
| ZNF571 | 127.0 |
| DPY30 | 126.0 |
| SNAPC3 | 118.0 |
| EED | 94.0 |
| RAD9B | 45.0 |
| ZNF461 | 33.0 |
| MED17 | 32.0 |
| ZNF688 | 31.0 |
| PPARGC1B | 22.0 |
| NR1H3 | 19.0 |
| FZR1 | 16.0 |
| ZNF727 | -20.0 |
| PPARD | -35.0 |
| VDR | -49.0 |
| ZNF304 | -59.0 |
| LSM10 | -75.0 |
| U2AF2 | -78.0 |
| RFC5 | -81.0 |
| PSMA2 | -85.0 |
| RABGGTA | -92.0 |
| ZNF584 | -120.0 |
| CAMK2B | -127.0 |
| TAF12 | -160.0 |
| ZNF454 | -161.0 |
| ZNF169 | -163.0 |
| NR1D2 | -174.0 |
| TFAP2A | -186.0 |
| WWP1 | -224.0 |
| ESRRG | -239.0 |
| COX5A | -245.0 |
| MTOR | -250.0 |
| CAMK4 | -265.0 |
| ANAPC4 | -310.0 |
| TEAD4 | -311.0 |
| RMI1 | -315.0 |
| TBP | -326.0 |
| NR2C1 | -336.0 |
| SMAD1 | -340.0 |
| TP53BP2 | -347.0 |
| H2AZ1 | -360.0 |
| INTS2 | -391.0 |
| ZNF136 | -394.0 |
| ZNF577 | -403.0 |
| RNU4ATAC | -420.0 |
| NR2F6 | -446.0 |
| ZNF589 | -447.0 |
| RRM2B | -473.0 |
| ZNF311 | -483.0 |
| GEM | -492.0 |
| PHAX | -508.0 |
| TSC2 | -513.0 |
| CNOT7 | -539.0 |
| H3C3 | -546.0 |
| ZNF133 | -552.0 |
| RBL1 | -621.0 |
| PAX5 | -626.0 |
| ZNF599 | -642.0 |
| ZNF549 | -647.0 |
| YES1 | -652.0 |
| LEF1 | -661.0 |
| ZNF704 | -672.0 |
| E2F6 | -673.0 |
| H2AC20 | -674.0 |
| ZNF74 | -675.0 |
| ZNF726 | -691.0 |
| RORB | -699.0 |
| FOXO1 | -711.0 |
| MNAT1 | -717.0 |
| ZNF202 | -738.0 |
| COL1A1 | -739.0 |
| CLP1 | -801.0 |
| ZNF213 | -844.0 |
| MAPK1 | -857.0 |
| PSMD14 | -865.0 |
| NOTCH2 | -868.0 |
| ZFPM1 | -876.0 |
| INTS3 | -901.0 |
| THOC1 | -929.0 |
| ZNF112 | -937.0 |
| LAMTOR3 | -947.0 |
| PSMD6 | -961.0 |
| CCND1 | -962.0 |
| POLR2L | -971.0 |
| SRSF5 | -979.0 |
| TFAP2C | -992.0 |
| ZNF12 | -995.0 |
| ZFP69 | -1000.0 |
| NOTCH1 | -1033.0 |
| ANAPC1 | -1043.0 |
| MED27 | -1054.0 |
| XPO1 | -1083.0 |
| ACTL6B | -1087.0 |
| ZNF425 | -1095.0 |
| SIRT3 | -1113.0 |
| ZNF547 | -1137.0 |
| ZSCAN32 | -1142.0 |
| SNRPB | -1171.0 |
| ZNF417 | -1180.0 |
| COX14 | -1185.0 |
| CDK6 | -1199.0 |
| RXRA | -1218.0 |
| ZNF665 | -1230.0 |
| CTNNB1 | -1232.0 |
| ZNF529 | -1238.0 |
| SGK1 | -1247.0 |
| ZNF490 | -1251.0 |
| RNF34 | -1258.0 |
| HDAC7 | -1261.0 |
| GATA4 | -1291.0 |
| PSMB7 | -1294.0 |
| UBE2S | -1361.0 |
| KCTD1 | -1382.0 |
| GPRIN1 | -1388.0 |
| H2BC6 | -1396.0 |
| NR2C2AP | -1411.0 |
| AGO3 | -1413.0 |
| TBL1XR1 | -1440.0 |
| USP7 | -1445.0 |
| PRKCQ | -1471.0 |
| CAT | -1504.0 |
| ZNF317 | -1506.0 |
| ZNF266 | -1531.0 |
| MAX | -1557.0 |
| DYRK2 | -1589.0 |
| ZNF197 | -1594.0 |
| BMAL1 | -1600.0 |
| NOC2L | -1604.0 |
| CALM1 | -1622.0 |
| ZNF433 | -1641.0 |
| ZNF263 | -1642.0 |
| ZNF772 | -1657.0 |
| BNIP3L | -1658.0 |
| ZNF287 | -1666.0 |
| BRPF1 | -1677.0 |
| TFAP2D | -1683.0 |
| ESR2 | -1685.0 |
| WWTR1 | -1688.0 |
| SETD9 | -1701.0 |
| SPP1 | -1710.0 |
| ELL | -1756.0 |
| CASP2 | -1770.0 |
| MAGOHB | -1800.0 |
| ZNF709 | -1807.0 |
| ZNF530 | -1819.0 |
| CNOT2 | -1828.0 |
| ZNF668 | -1845.0 |
| POU4F1 | -1865.0 |
| MAPKAP1 | -1867.0 |
| ZNF761 | -1868.0 |
| SATB2 | -1882.0 |
| YWHAG | -1887.0 |
| TCF3 | -1910.0 |
| SLC38A9 | -1912.0 |
| PRDX2 | -1921.0 |
| PLK3 | -1922.0 |
| ZNF215 | -1929.0 |
| FAS | -1940.0 |
| HEY1 | -1949.0 |
| RBFOX1 | -1979.0 |
| YY1 | -1989.0 |
| PHF20 | -1999.0 |
| ZNF740 | -2004.0 |
| ZNF703 | -2011.0 |
| TSC1 | -2023.0 |
| TGFA | -2032.0 |
| MAP2K6 | -2038.0 |
| ZNF19 | -2047.0 |
| PTEN | -2093.0 |
| H2BC4 | -2094.0 |
| PPP2R1A | -2107.0 |
| H2BC12 | -2115.0 |
| IL2 | -2134.0 |
| TFDP1 | -2156.0 |
| JMY | -2164.0 |
| ARID2 | -2226.0 |
| MAPK11 | -2236.0 |
| HIPK2 | -2250.0 |
| THOC5 | -2259.0 |
| ICE2 | -2282.0 |
| RXRG | -2285.0 |
| PSMB10 | -2290.0 |
| LIFR | -2307.0 |
| NR1H4 | -2316.0 |
| GTF2H5 | -2337.0 |
| EP300 | -2354.0 |
| PSMB6 | -2408.0 |
| CREBBP | -2409.0 |
| EZH2 | -2415.0 |
| BANP | -2423.0 |
| TNRC6A | -2432.0 |
| ZNF680 | -2434.0 |
| CUL1 | -2437.0 |
| AKT2 | -2480.0 |
| ZNF419 | -2498.0 |
| ING5 | -2508.0 |
| CNOT3 | -2521.0 |
| SUMO1 | -2534.0 |
| UBE2C | -2539.0 |
| AKT1 | -2548.0 |
| ZNF790 | -2564.0 |
| PSMD9 | -2570.0 |
| MYC | -2593.0 |
| COX18 | -2600.0 |
| MED24 | -2629.0 |
| UBE2E1 | -2647.0 |
| ZNF140 | -2655.0 |
| IL2RA | -2662.0 |
| ZNF268 | -2703.0 |
| PRKAB1 | -2706.0 |
| PF4 | -2744.0 |
| PRKAA1 | -2747.0 |
| ZNF573 | -2765.0 |
| ZNF570 | -2778.0 |
| ARID1B | -2787.0 |
| CPSF3 | -2788.0 |
| PRKAG2 | -2851.0 |
| RUNX3 | -2854.0 |
| WRN | -2909.0 |
| ZNF724 | -2959.0 |
| MED23 | -2961.0 |
| RORA | -2965.0 |
| ZNF445 | -2987.0 |
| GTF2E2 | -3037.0 |
| NOTCH4 | -3079.0 |
| ZIK1 | -3097.0 |
| COX5B | -3104.0 |
| TNFRSF10B | -3105.0 |
| CLDN5 | -3124.0 |
| NCBP2 | -3139.0 |
| ZNF714 | -3140.0 |
| ESRRA | -3172.0 |
| TRIM33 | -3178.0 |
| ZNF430 | -3202.0 |
| ZNF30 | -3205.0 |
| ZNF214 | -3206.0 |
| L3MBTL1 | -3217.0 |
| POLR2B | -3234.0 |
| ELOA2 | -3237.0 |
| IWS1 | -3249.0 |
| MMP13 | -3255.0 |
| NR3C2 | -3257.0 |
| ZNF485 | -3260.0 |
| SP1 | -3275.0 |
| SETD1A | -3286.0 |
| ZNF398 | -3333.0 |
| NR4A1 | -3337.0 |
| PHC3 | -3360.0 |
| IHH | -3373.0 |
| MED16 | -3376.0 |
| PRKAA2 | -3400.0 |
| TAF4 | -3407.0 |
| TNFRSF18 | -3412.0 |
| CR1 | -3419.0 |
| SIRT1 | -3421.0 |
| RICTOR | -3439.0 |
| ZNF506 | -3493.0 |
| CCNA2 | -3495.0 |
| HDAC4 | -3592.0 |
| CDK9 | -3594.0 |
| SMYD2 | -3601.0 |
| ZNF273 | -3612.0 |
| CARM1 | -3614.0 |
| ZNF792 | -3619.0 |
| ZNF736 | -3623.0 |
| AFF4 | -3636.0 |
| ZNF493 | -3659.0 |
| TNRC6C | -3711.0 |
| CCN2 | -3717.0 |
| MED7 | -3721.0 |
| PLK2 | -3722.0 |
| MET | -3729.0 |
| ZNF18 | -3748.0 |
| RMI2 | -3754.0 |
| UBA52 | -3755.0 |
| NOTCH3 | -3760.0 |
| ANAPC7 | -3780.0 |
| PLXNA4 | -3788.0 |
| ZNF585A | -3836.0 |
| CPSF4 | -3838.0 |
| TCF12 | -3867.0 |
| NBN | -3893.0 |
| ZFHX3 | -3913.0 |
| TJP1 | -3931.0 |
| MYL9 | -3932.0 |
| SCMH1 | -3933.0 |
| RUNX2 | -3960.0 |
| NELFA | -3973.0 |
| CAMK2D | -3981.0 |
| RHEB | -4039.0 |
| SCO1 | -4041.0 |
| PIP4K2C | -4044.0 |
| ZNF774 | -4061.0 |
| APAF1 | -4071.0 |
| ZNF71 | -4100.0 |
| SOX2 | -4140.0 |
| SCO2 | -4149.0 |
| SRC | -4161.0 |
| TEAD1 | -4199.0 |
| PDPK1 | -4211.0 |
| ZNF514 | -4223.0 |
| KRBOX5 | -4226.0 |
| SMAD3 | -4228.0 |
| ZIM3 | -4237.0 |
| ZNF721 | -4245.0 |
| SRSF11 | -4246.0 |
| HES1 | -4252.0 |
| REST | -4269.0 |
| SUPT5H | -4276.0 |
| COX7A2L | -4311.0 |
| RRAGA | -4390.0 |
| RAD51 | -4393.0 |
| NCOR1 | -4394.0 |
| MAML2 | -4415.0 |
| NCOR2 | -4436.0 |
| CDC73 | -4460.0 |
| ZNF595 | -4471.0 |
| CNOT6L | -4491.0 |
| ANAPC16 | -4502.0 |
| ZNF691 | -4503.0 |
| GTF2F1 | -4505.0 |
| ATR | -4506.0 |
| TAF3 | -4514.0 |
| CRADD | -4557.0 |
| TNFRSF10D | -4570.0 |
| ZNF180 | -4573.0 |
| ZNF677 | -4621.0 |
| GP1BA | -4623.0 |
| ZNF669 | -4627.0 |
| ZNF17 | -4668.0 |
| CNOT10 | -4682.0 |
| MED4 | -4685.0 |
| PSMB5 | -4687.0 |
| GPX2 | -4690.0 |
| HEY2 | -4714.0 |
| SKP2 | -4745.0 |
| CDK5R1 | -4748.0 |
| POLR2F | -4762.0 |
| INTS10 | -4774.0 |
| ZNF200 | -4802.0 |
| PCGF6 | -4805.0 |
| ZFP2 | -4824.0 |
| SMAD6 | -4836.0 |
| AGO2 | -4870.0 |
| TAF2 | -4881.0 |
| YAF2 | -4882.0 |
| H2BC9 | -4907.5 |
| H3C7 | -4907.5 |
| CDK7 | -4917.0 |
| ZNF718 | -4939.0 |
| H4C5 | -4941.0 |
| RBFOX3 | -4944.0 |
| ZNF521 | -4948.0 |
| NELFB | -4963.0 |
| RFC3 | -4967.0 |
| OPRM1 | -4973.0 |
| ZNF415 | -4981.0 |
| RRM2 | -4995.0 |
| TCF7L2 | -5003.0 |
| ZNF786 | -5038.0 |
| INTS13 | -5046.0 |
| CSF1R | -5061.0 |
| ELF2 | -5067.0 |
| MED13 | -5103.0 |
| ZNF555 | -5113.0 |
| KMT2C | -5146.0 |
| ZNF707 | -5148.0 |
| ZNF550 | -5150.0 |
| COX19 | -5160.0 |
| PSMD7 | -5198.0 |
| ATRIP | -5201.0 |
| ABCA6 | -5208.0 |
| MLLT3 | -5211.0 |
| ZNF568 | -5212.0 |
| MGA | -5238.0 |
| GTF2B | -5239.0 |
| ZNF775 | -5245.0 |
| FOXO3 | -5268.0 |
| EPC1 | -5272.0 |
| RARB | -5281.0 |
| EGFR | -5320.0 |
| HAND2 | -5333.0 |
| PSMD4 | -5337.0 |
| RPAP2 | -5339.0 |
| YAP1 | -5356.0 |
| SERPINE1 | -5361.0 |
| INTS1 | -5384.0 |
| COX8A | -5390.0 |
| UBE2D1 | -5394.0 |
| PLAGL1 | -5415.0 |
| FKBP5 | -5427.0 |
| POLR2C | -5430.0 |
| MAPK3 | -5444.0 |
| ZNF559 | -5451.0 |
| ZNF26 | -5457.0 |
| OPRK1 | -5461.0 |
| HIVEP3 | -5489.0 |
| RNMT | -5497.0 |
| NR6A1 | -5505.0 |
| ZNF100 | -5522.0 |
| SMURF2 | -5528.0 |
| NR1H2 | -5551.0 |
| INTS8 | -5559.0 |
| SMARCB1 | -5562.0 |
| ZNF257 | -5583.0 |
| AKT3 | -5586.0 |
| CHD3 | -5589.0 |
| ZNF331 | -5600.0 |
| CDK13 | -5608.0 |
| OCLN | -5612.0 |
| NEDD4L | -5629.0 |
| FANCC | -5640.0 |
| ZNF33B | -5675.0 |
| ZNF480 | -5699.0 |
| ITGBL1 | -5704.0 |
| ZNF583 | -5751.0 |
| ZNF250 | -5756.0 |
| ATAD2 | -5761.0 |
| H2BC21 | -5773.0 |
| LGALS3 | -5792.0 |
| TOPBP1 | -5800.0 |
| ZNF627 | -5811.0 |
| PSMB1 | -5858.0 |
| AXIN1 | -5863.0 |
| ZNF20 | -5867.0 |
| SRRM1 | -5879.0 |
| DLX6 | -5885.0 |
| ZSCAN25 | -5900.0 |
| PAPOLA | -5925.0 |
| KMT2B | -5928.0 |
| ZNF496 | -5982.0 |
| ZNF561 | -5998.0 |
| CAMK2G | -6002.0 |
| GSK3B | -6007.0 |
| POLR2J | -6011.0 |
| ZNF585B | -6031.0 |
| TNFRSF10A | -6065.0 |
| ZNF347 | -6075.0 |
| TNFRSF10C | -6105.0 |
| NABP1 | -6114.0 |
| ZNF649 | -6122.0 |
| MED20 | -6132.0 |
| ACTL6A | -6145.0 |
| CDK1 | -6160.0 |
| MTA2 | -6196.0 |
| POLR2H | -6261.0 |
| ZNF681 | -6264.0 |
| ZNF620 | -6287.0 |
| FBXW7 | -6321.0 |
| NFATC2 | -6326.0 |
| MAML3 | -6383.0 |
| MSTN | -6410.0 |
| RAD50 | -6431.0 |
| ZNF777 | -6461.0 |
| ARNT2 | -6467.0 |
| HSPD1 | -6508.0 |
| KAT2A | -6518.0 |
| HIPK1 | -6525.0 |
| NFYB | -6538.0 |
| RNF2 | -6542.0 |
| ZNF79 | -6547.0 |
| CAMK2A | -6562.0 |
| BRPF3 | -6592.0 |
| AIFM2 | -6613.0 |
| SREBF1 | -6640.0 |
| CDK5 | -6642.0 |
| RORC | -6673.0 |
| H2BC26 | -6695.0 |
| ZNF135 | -6697.0 |
| PHC2 | -6705.0 |
| E2F4 | -6771.0 |
| ZNF519 | -6794.0 |
| MLST8 | -6804.0 |
| TNKS1BP1 | -6850.0 |
| IQSEC3 | -6884.0 |
| ZNF286A | -6902.0 |
| SOX9 | -6913.0 |
| ESRRB | -6928.0 |
| THRB | -6930.0 |
| WDR5 | -6936.0 |
| HDAC9 | -6937.0 |
| ZNF569 | -6945.0 |
| E2F7 | -6967.0 |
| ZNF605 | -6992.0 |
| STK11 | -7002.0 |
| ZNF804B | -7010.0 |
| TMEM219 | -7062.0 |
| MLLT1 | -7073.0 |
| ZNF2 | -7112.0 |
| ZNF764 | -7114.0 |
| INTS11 | -7181.0 |
| SUPT4H1 | -7200.0 |
| PPP2CB | -7216.0 |
| NFKB1 | -7273.0 |
| ZNF254 | -7274.0 |
| STEAP3 | -7284.0 |
| ZNF382 | -7292.0 |
| ZNF285 | -7346.0 |
| ZNF667 | -7371.0 |
| ZFP1 | -7372.0 |
| WWOX | -7427.0 |
| KCTD15 | -7432.0 |
| SOD2 | -7470.0 |
| PIDD1 | -7542.0 |
| PSMD8 | -7723.0 |
| ZNF717 | -7752.0 |
| FOXG1 | -7782.0 |
| ZNF582 | -7811.0 |
| GCK | -7823.0 |
| CITED2 | -7882.0 |
| SMAD2 | -7888.0 |
| RUNX1 | -7923.0 |
| ZNF483 | -7935.0 |
| ZNF484 | -7943.0 |
| ZNF773 | -7968.0 |
| ZFP14 | -7976.0 |
| TP63 | -8024.0 |
| RPTOR | -8028.0 |
| FIP1L1 | -8037.0 |
| HNF4G | -8038.0 |
| ZNF682 | -8077.0 |
| RPA3 | -8086.0 |
| RELA | -8093.0 |
| TEAD3 | -8097.0 |
| NLRC4 | -8113.0 |
| ZNF385A | -8149.0 |
| KCNIP3 | -8172.0 |
| ZNF778 | -8205.0 |
| PPP2R1B | -8245.0 |
| SOCS3 | -8251.0 |
| FURIN | -8263.0 |
| PTPN4 | -8273.0 |
| POLR2G | -8279.0 |
| ZNF25 | -8280.0 |
| ABL1 | -8289.0 |
| GLI3 | -8296.0 |
| CSF2 | -8316.0 |
| ZNF556 | -8329.0 |
| ZNF708 | -8345.0 |
| TP53I3 | -8454.0 |
| ZNF600 | -8464.0 |
| BRD1 | -8478.0 |
| INTS4 | -8479.0 |
| GTF2A2 | -8491.0 |
| AUTS2 | -8495.0 |
| ZNF875 | -8527.0 |
| RET | -8529.0 |
| SIN3B | -8543.0 |
| KRBA1 | -8545.0 |
| ZNF676 | -8564.0 |
| H2AC14 | -8606.0 |
| AGRP | -8628.0 |
| PPARGC1A | -8665.0 |
| FBXO32 | -8683.0 |
| H2BC14 | -8730.0 |
| CTSL | -8793.0 |
| FANCI | -8803.0 |
| ZNF670 | -8893.0 |
| SERPINB13 | -8941.0 |
| ZNF441 | -8956.0 |
| SLBP | -9081.0 |
| MIR24-1 | -9122.0 |
| NR2E3 | -9166.0 |
| BGLAP | -9170.0 |
| GLI2 | -9196.0 |
| CASP1 | -9200.0 |
| ZNF750 | -9228.0 |
| ZNF610 | -9271.0 |
| H4C9 | -9282.0 |
| ZNF114 | -9299.0 |
| MAGOH | -9309.0 |
| ZNF730 | -9331.0 |
| SFN | -9368.0 |
| ZNF586 | -9409.0 |
| ZNF205 | -9410.0 |
| ZNF439 | -9486.0 |
| PSMD5 | -9524.0 |
| CGA | -9566.0 |
| ZNF45 | -9582.0 |
| NDRG1 | -9608.0 |
| ZNF212 | -9616.0 |
| ZIM2 | -9736.0 |
| ZNF486 | -9773.0 |
| IFNG | -9825.0 |
| IL3 | -9827.0 |
| ZNF471 | -9865.0 |
| CCNE1 | -9930.0 |
| FOXO6 | -10020.0 |
| TP53AIP1 | -10087.0 |
| ZNF479 | -10184.0 |
| H2AC18 | -10224.5 |
| H2AC19 | -10224.5 |
| RETN | -10246.0 |
| ZNF558 | -10329.0 |
| ZNF679 | -10568.0 |
| UCMA | -10705.0 |
REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE
| 271 | |
|---|---|
| set | REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE |
| setSize | 105 |
| pANOVA | 1.44e-07 |
| s.dist | 0.297 |
| p.adjustANOVA | 3.39e-05 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| SEC61B | 10362.0 |
| RPL14 | 10215.0 |
| RPL18 | 10082.0 |
| RPL10A | 10035.0 |
| SRP14 | 9909.0 |
| RPL23A | 9830.0 |
| RPS13 | 9737.0 |
| SSR3 | 9615.0 |
| RPL38 | 9474.0 |
| RPS21 | 9255.0 |
| RPLP0 | 9213.0 |
| DDOST | 9201.0 |
| RPL29 | 9165.0 |
| RPS3A | 8946.0 |
| RPL28 | 8875.0 |
| SRP72 | 8776.0 |
| RPL36AL | 8459.5 |
| RPL22L1 | 8449.0 |
| RPL31 | 8273.0 |
| RPS24 | 8170.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SEC61B | 10362.0 |
| RPL14 | 10215.0 |
| RPL18 | 10082.0 |
| RPL10A | 10035.0 |
| SRP14 | 9909.0 |
| RPL23A | 9830.0 |
| RPS13 | 9737.0 |
| SSR3 | 9615.0 |
| RPL38 | 9474.0 |
| RPS21 | 9255.0 |
| RPLP0 | 9213.0 |
| DDOST | 9201.0 |
| RPL29 | 9165.0 |
| RPS3A | 8946.0 |
| RPL28 | 8875.0 |
| SRP72 | 8776.0 |
| RPL36AL | 8459.5 |
| RPL22L1 | 8449.0 |
| RPL31 | 8273.0 |
| RPS24 | 8170.0 |
| RPS23 | 8094.0 |
| SRP9 | 8071.0 |
| RPL26 | 8016.0 |
| SRP54 | 8000.0 |
| RPS20 | 7907.0 |
| RPN1 | 7882.0 |
| SSR2 | 7765.0 |
| RPS29 | 7621.0 |
| RPL34 | 7423.0 |
| RPS19 | 7419.0 |
| RPS3 | 7411.0 |
| RPL41 | 7335.0 |
| RPL6 | 7304.0 |
| RPS27A | 7120.0 |
| RPL23 | 6935.0 |
| FAU | 6424.0 |
| RPL11 | 6414.0 |
| RPL21 | 6341.0 |
| RPL13 | 6125.0 |
| RPS26 | 6058.0 |
| SPCS2 | 5997.0 |
| RPL7A | 5991.0 |
| RPS16 | 5896.0 |
| RPL8 | 5822.0 |
| SEC11A | 5794.0 |
| RPS7 | 5716.0 |
| RPL26L1 | 5531.0 |
| RPS8 | 5431.0 |
| RPL37A | 5292.0 |
| RPL3L | 5206.0 |
| SEC61G | 5145.0 |
| RPL13A | 5131.5 |
| RPS10 | 5058.0 |
| RPL19 | 4913.0 |
| RPS18 | 4856.0 |
| SEC61A1 | 4835.0 |
| SRPRB | 4813.0 |
| RPL9 | 4760.0 |
| RPS27 | 4711.0 |
| RPS12 | 4501.0 |
| RPL35 | 4434.0 |
| RPL35A | 4218.0 |
| RPL17 | 4202.0 |
| TRAM1 | 3904.0 |
| RPSA | 3281.0 |
| RPL3 | 3240.0 |
| SRP19 | 2954.0 |
| RPL12 | 2822.0 |
| RPS28 | 2669.0 |
| RPL27A | 2494.0 |
| RPL15 | 2382.0 |
| RPL32 | 2362.0 |
| RPS15A | 2095.0 |
| RPS25 | 1988.0 |
| RPLP1 | 1762.0 |
| SEC11C | 1578.0 |
| RPL7 | 1442.0 |
| SPCS1 | 1097.0 |
| RPL5 | -139.0 |
| RPS2 | -1028.0 |
| RPS14 | -1691.0 |
| RPL30 | -2061.0 |
| SRP68 | -2063.0 |
| RPS5 | -2579.0 |
| RPS6 | -2673.0 |
| RPL39L | -3132.0 |
| RPL37 | -3282.0 |
| UBA52 | -3755.0 |
| SEC61A2 | -4055.0 |
| RPS15 | -4150.0 |
| RPL24 | -4644.0 |
| RPS9 | -4650.0 |
| SSR1 | -4735.0 |
| RPL4 | -5128.0 |
| RPL27 | -5306.0 |
| RPL18A | -5425.0 |
| RPL22 | -5765.0 |
| RPLP2 | -5777.0 |
| RPS27L | -5945.0 |
| SRPRA | -7160.0 |
| RPN2 | -7620.0 |
| RPL36 | -8155.0 |
| RPS11 | -8626.0 |
| SPCS3 | -9800.0 |
| RPL10L | -10090.0 |
REACTOME_RRNA_PROCESSING
| 1148 | |
|---|---|
| set | REACTOME_RRNA_PROCESSING |
| setSize | 192 |
| pANOVA | 3.11e-07 |
| s.dist | 0.214 |
| p.adjustANOVA | 6.39e-05 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL14 | 10215 |
| RPL18 | 10082 |
| RPL10A | 10035 |
| ISG20L2 | 9875 |
| EXOSC5 | 9863 |
| RPL23A | 9830 |
| RPS13 | 9737 |
| UTP4 | 9709 |
| DIMT1 | 9686 |
| RPL38 | 9474 |
| EXOSC1 | 9393 |
| RPS21 | 9255 |
| IMP3 | 9232 |
| RPLP0 | 9213 |
| RPL29 | 9165 |
| IMP4 | 9147 |
| RPP40 | 9016 |
| RPP25 | 8979 |
| RPS3A | 8946 |
| SNU13 | 8897 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL14 | 10215.0 |
| RPL18 | 10082.0 |
| RPL10A | 10035.0 |
| ISG20L2 | 9875.0 |
| EXOSC5 | 9863.0 |
| RPL23A | 9830.0 |
| RPS13 | 9737.0 |
| UTP4 | 9709.0 |
| DIMT1 | 9686.0 |
| RPL38 | 9474.0 |
| EXOSC1 | 9393.0 |
| RPS21 | 9255.0 |
| IMP3 | 9232.0 |
| RPLP0 | 9213.0 |
| RPL29 | 9165.0 |
| IMP4 | 9147.0 |
| RPP40 | 9016.0 |
| RPP25 | 8979.0 |
| RPS3A | 8946.0 |
| SNU13 | 8897.0 |
| RPL28 | 8875.0 |
| UTP6 | 8835.0 |
| TRMT10C | 8680.0 |
| RPL36AL | 8459.5 |
| RPL22L1 | 8449.0 |
| RPL31 | 8273.0 |
| RPS24 | 8170.0 |
| RPS23 | 8094.0 |
| RPL26 | 8016.0 |
| DDX21 | 7989.0 |
| EXOSC9 | 7985.0 |
| NOL11 | 7955.0 |
| RPS20 | 7907.0 |
| RPS29 | 7621.0 |
| DIS3 | 7503.0 |
| RPL34 | 7423.0 |
| RPS19 | 7419.0 |
| RPS3 | 7411.0 |
| GAR1 | 7394.0 |
| RPL41 | 7335.0 |
| RPL6 | 7304.0 |
| DCAF13 | 7270.0 |
| WDR3 | 7237.0 |
| PWP2 | 7235.0 |
| PES1 | 7181.0 |
| RPS27A | 7120.0 |
| RPL23 | 6935.0 |
| SENP3 | 6893.0 |
| EXOSC4 | 6868.0 |
| NAT10 | 6830.0 |
| BMS1 | 6826.0 |
| RPP21 | 6718.0 |
| FAU | 6424.0 |
| RPL11 | 6414.0 |
| RPL21 | 6341.0 |
| NHP2 | 6142.0 |
| RPL13 | 6125.0 |
| RPS26 | 6058.0 |
| RPL7A | 5991.0 |
| RPP14 | 5987.0 |
| TEX10 | 5932.0 |
| RPS16 | 5896.0 |
| MPHOSPH10 | 5885.0 |
| RPL8 | 5822.0 |
| FCF1 | 5733.0 |
| RPS7 | 5716.0 |
| RPP38 | 5714.0 |
| TRMT112 | 5611.0 |
| RPL26L1 | 5531.0 |
| NOP2 | 5509.0 |
| RPS8 | 5431.0 |
| WDR46 | 5343.0 |
| RPL37A | 5292.0 |
| MRM3 | 5238.0 |
| RPL3L | 5206.0 |
| DDX47 | 5191.0 |
| RPL13A | 5131.5 |
| RPS10 | 5058.0 |
| RPL19 | 4913.0 |
| RPS18 | 4856.0 |
| RPL9 | 4760.0 |
| RPS27 | 4711.0 |
| RPS12 | 4501.0 |
| RPL35 | 4434.0 |
| EXOSC3 | 4242.0 |
| RPL35A | 4218.0 |
| RPL17 | 4202.0 |
| EBNA1BP2 | 4140.0 |
| KRR1 | 4067.0 |
| BOP1 | 3984.0 |
| NOL12 | 3746.0 |
| UTP11 | 3571.0 |
| XRN2 | 3496.0 |
| WDR36 | 3393.0 |
| RPSA | 3281.0 |
| RPL3 | 3240.0 |
| CSNK1D | 3179.0 |
| FTSJ3 | 3085.0 |
| NOP10 | 3084.0 |
| EXOSC7 | 3025.0 |
| RBM28 | 2908.0 |
| RPL12 | 2822.0 |
| NIP7 | 2677.0 |
| RPS28 | 2669.0 |
| NSUN4 | 2656.0 |
| RRP9 | 2631.0 |
| RPL27A | 2494.0 |
| RIOK3 | 2488.0 |
| NCL | 2444.0 |
| RPL15 | 2382.0 |
| RPL32 | 2362.0 |
| RPS15A | 2095.0 |
| MTREX | 1999.0 |
| RPS25 | 1988.0 |
| EMG1 | 1863.0 |
| UTP20 | 1796.0 |
| RPLP1 | 1762.0 |
| UTP18 | 1686.0 |
| NOC4L | 1635.0 |
| MRM1 | 1605.0 |
| WDR18 | 1532.0 |
| FBL | 1467.0 |
| RPL7 | 1442.0 |
| DDX52 | 1328.0 |
| RRP1 | 1280.0 |
| PRORP | 1099.0 |
| NOP58 | 789.0 |
| DDX49 | 519.0 |
| PDCD11 | 314.0 |
| TSR1 | 225.0 |
| EXOSC8 | -119.0 |
| RPL5 | -139.0 |
| PELP1 | -199.0 |
| RRP36 | -455.0 |
| WDR43 | -495.0 |
| TFB1M | -523.0 |
| MTERF4 | -537.0 |
| C1D | -558.0 |
| EXOSC10 | -564.0 |
| GNL3 | -792.0 |
| UTP3 | -923.0 |
| LTV1 | -957.0 |
| THUMPD1 | -968.0 |
| RPS2 | -1028.0 |
| PNO1 | -1296.0 |
| EXOSC6 | -1460.0 |
| RPS14 | -1691.0 |
| WDR75 | -1740.0 |
| TBL3 | -1859.0 |
| RPL30 | -2061.0 |
| NOL6 | -2304.0 |
| RPS5 | -2579.0 |
| RPS6 | -2673.0 |
| RCL1 | -2819.0 |
| MRM2 | -2922.0 |
| RPL39L | -3132.0 |
| DHX37 | -3197.0 |
| NOB1 | -3201.0 |
| RPL37 | -3282.0 |
| RRP7A | -3304.0 |
| WDR12 | -3727.0 |
| UBA52 | -3755.0 |
| RPS15 | -4150.0 |
| HEATR1 | -4265.0 |
| MPHOSPH6 | -4287.0 |
| UTP25 | -4611.0 |
| RPL24 | -4644.0 |
| RIOK2 | -4648.0 |
| RPS9 | -4650.0 |
| RPL4 | -5128.0 |
| RPL27 | -5306.0 |
| NOP56 | -5343.0 |
| RPL18A | -5425.0 |
| RIOK1 | -5473.0 |
| UTP15 | -5740.0 |
| RPL22 | -5765.0 |
| RPLP2 | -5777.0 |
| RPP30 | -5830.0 |
| BUD23 | -5862.0 |
| RPS27L | -5945.0 |
| BYSL | -6382.0 |
| EXOSC2 | -6711.0 |
| TSR3 | -6934.0 |
| CSNK1E | -7527.0 |
| RPL36 | -8155.0 |
| NOP14 | -8179.0 |
| RPS11 | -8626.0 |
| NOL9 | -8684.0 |
| UTP14C | -8778.0 |
| ERI1 | -9535.0 |
| RPL10L | -10090.0 |
| ELAC2 | -10097.0 |
REACTOME_CELLULAR_RESPONSE_TO_STARVATION
| 1582 | |
|---|---|
| set | REACTOME_CELLULAR_RESPONSE_TO_STARVATION |
| setSize | 147 |
| pANOVA | 3.6e-07 |
| s.dist | 0.243 |
| p.adjustANOVA | 6.56e-05 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL14 | 10215 |
| RPL18 | 10082 |
| ATP6V1G2 | 10077 |
| RPL10A | 10035 |
| ATP6V0E1 | 9908 |
| RPL23A | 9830 |
| RPS13 | 9737 |
| ATP6V0E2 | 9509 |
| ATF4 | 9477 |
| RPL38 | 9474 |
| LAMTOR4 | 9268 |
| RPS21 | 9255 |
| RPLP0 | 9213 |
| RPL29 | 9165 |
| SESN2 | 9164 |
| RPS3A | 8946 |
| RPL28 | 8875 |
| ATP6V0D2 | 8747 |
| ATP6V1F | 8669 |
| ATP6V1G1 | 8624 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL14 | 10215.0 |
| RPL18 | 10082.0 |
| ATP6V1G2 | 10077.0 |
| RPL10A | 10035.0 |
| ATP6V0E1 | 9908.0 |
| RPL23A | 9830.0 |
| RPS13 | 9737.0 |
| ATP6V0E2 | 9509.0 |
| ATF4 | 9477.0 |
| RPL38 | 9474.0 |
| LAMTOR4 | 9268.0 |
| RPS21 | 9255.0 |
| RPLP0 | 9213.0 |
| RPL29 | 9165.0 |
| SESN2 | 9164.0 |
| RPS3A | 8946.0 |
| RPL28 | 8875.0 |
| ATP6V0D2 | 8747.0 |
| ATP6V1F | 8669.0 |
| ATP6V1G1 | 8624.0 |
| ATP6V1C1 | 8602.0 |
| LAMTOR2 | 8526.0 |
| RPL36AL | 8459.5 |
| RPL22L1 | 8449.0 |
| ATP6V1E1 | 8281.0 |
| RPL31 | 8273.0 |
| FNIP1 | 8229.0 |
| RPS24 | 8170.0 |
| RPS23 | 8094.0 |
| RPL26 | 8016.0 |
| RPS20 | 7907.0 |
| RPS29 | 7621.0 |
| RPL34 | 7423.0 |
| RPS19 | 7419.0 |
| RPS3 | 7411.0 |
| RPL41 | 7335.0 |
| RPL6 | 7304.0 |
| RPS27A | 7120.0 |
| RPL23 | 6935.0 |
| SEH1L | 6838.0 |
| ATP6V1B2 | 6805.0 |
| DDIT3 | 6748.0 |
| FAU | 6424.0 |
| RPL11 | 6414.0 |
| RPL21 | 6341.0 |
| RPL13 | 6125.0 |
| RRAGC | 6080.0 |
| RPS26 | 6058.0 |
| RPL7A | 5991.0 |
| TRIB3 | 5967.0 |
| RPS16 | 5896.0 |
| RPL8 | 5822.0 |
| GCN1 | 5802.0 |
| RPS7 | 5716.0 |
| DEPDC5 | 5608.0 |
| RPL26L1 | 5531.0 |
| ATP6V1A | 5492.0 |
| RPS8 | 5431.0 |
| RPL37A | 5292.0 |
| IMPACT | 5258.0 |
| RPL3L | 5206.0 |
| RPL13A | 5131.5 |
| RPS10 | 5058.0 |
| RPL19 | 4913.0 |
| RPS18 | 4856.0 |
| RPL9 | 4760.0 |
| CASTOR1 | 4748.0 |
| RPS27 | 4711.0 |
| CEBPB | 4682.0 |
| ATP6V0C | 4507.0 |
| RPS12 | 4501.0 |
| RPL35 | 4434.0 |
| SESN1 | 4424.0 |
| ATP6V1D | 4345.0 |
| MIOS | 4275.0 |
| RPL35A | 4218.0 |
| RPL17 | 4202.0 |
| FNIP2 | 4046.0 |
| KICS2 | 4008.0 |
| LAMTOR5 | 3821.0 |
| ATF2 | 3606.0 |
| NPRL2 | 3561.0 |
| ATP6V1B1 | 3349.0 |
| TCIRG1 | 3340.0 |
| RPSA | 3281.0 |
| RPL3 | 3240.0 |
| ATP6V1E2 | 3127.0 |
| RPL12 | 2822.0 |
| RRAGD | 2813.0 |
| RPS28 | 2669.0 |
| EIF2S1 | 2623.0 |
| RPL27A | 2494.0 |
| RPL15 | 2382.0 |
| RPL32 | 2362.0 |
| RPS15A | 2095.0 |
| EIF2S2 | 2093.0 |
| RPS25 | 1988.0 |
| ITFG2 | 1934.0 |
| RPLP1 | 1762.0 |
| LAMTOR1 | 1723.0 |
| RPL7 | 1442.0 |
| ASNS | 351.0 |
| RPL5 | -139.0 |
| MTOR | -250.0 |
| NPRL3 | -752.0 |
| LAMTOR3 | -947.0 |
| RPS2 | -1028.0 |
| EIF2AK4 | -1363.0 |
| RPS14 | -1691.0 |
| SLC38A9 | -1912.0 |
| ATP6V1H | -2022.0 |
| RPL30 | -2061.0 |
| WDR59 | -2110.0 |
| ATF3 | -2158.0 |
| RPS5 | -2579.0 |
| ATP6V0D1 | -2636.0 |
| RPS6 | -2673.0 |
| ATP6V1C2 | -2734.0 |
| RPL39L | -3132.0 |
| RPL37 | -3282.0 |
| UBA52 | -3755.0 |
| RHEB | -4039.0 |
| RPS15 | -4150.0 |
| RRAGA | -4390.0 |
| WDR24 | -4414.0 |
| FLCN | -4462.0 |
| CEBPG | -4609.0 |
| RPL24 | -4644.0 |
| RPS9 | -4650.0 |
| RPL4 | -5128.0 |
| RPL27 | -5306.0 |
| RPL18A | -5425.0 |
| SEC13 | -5670.0 |
| RPL22 | -5765.0 |
| RPLP2 | -5777.0 |
| ATP6V0B | -5878.0 |
| RPS27L | -5945.0 |
| KPTN | -6603.0 |
| MLST8 | -6804.0 |
| SH3BP4 | -7254.0 |
| SZT2 | -7526.0 |
| RPTOR | -8028.0 |
| RPL36 | -8155.0 |
| BMT2 | -8482.0 |
| ATP6V1G3 | -8586.0 |
| RPS11 | -8626.0 |
| RPL10L | -10090.0 |
REACTOME_EUKARYOTIC_TRANSLATION_INITIATION
| 1149 | |
|---|---|
| set | REACTOME_EUKARYOTIC_TRANSLATION_INITIATION |
| setSize | 110 |
| pANOVA | 5.47e-07 |
| s.dist | 0.276 |
| p.adjustANOVA | 8.97e-05 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL14 | 10215.0 |
| RPL18 | 10082.0 |
| RPL10A | 10035.0 |
| EIF4A1 | 10017.0 |
| RPL23A | 9830.0 |
| RPS13 | 9737.0 |
| RPL38 | 9474.0 |
| RPS21 | 9255.0 |
| RPLP0 | 9213.0 |
| RPL29 | 9165.0 |
| RPS3A | 8946.0 |
| RPL28 | 8875.0 |
| EIF3F | 8569.0 |
| PABPC1 | 8543.0 |
| RPL36AL | 8459.5 |
| RPL22L1 | 8449.0 |
| RPL31 | 8273.0 |
| EIF3E | 8263.0 |
| RPS24 | 8170.0 |
| RPS23 | 8094.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL14 | 10215.0 |
| RPL18 | 10082.0 |
| RPL10A | 10035.0 |
| EIF4A1 | 10017.0 |
| RPL23A | 9830.0 |
| RPS13 | 9737.0 |
| RPL38 | 9474.0 |
| RPS21 | 9255.0 |
| RPLP0 | 9213.0 |
| RPL29 | 9165.0 |
| RPS3A | 8946.0 |
| RPL28 | 8875.0 |
| EIF3F | 8569.0 |
| PABPC1 | 8543.0 |
| RPL36AL | 8459.5 |
| RPL22L1 | 8449.0 |
| RPL31 | 8273.0 |
| EIF3E | 8263.0 |
| RPS24 | 8170.0 |
| RPS23 | 8094.0 |
| RPL26 | 8016.0 |
| RPS20 | 7907.0 |
| EIF2B1 | 7775.0 |
| RPS29 | 7621.0 |
| EIF3D | 7612.0 |
| EIF4E | 7566.0 |
| EIF3K | 7541.0 |
| EIF3J | 7482.0 |
| RPL34 | 7423.0 |
| RPS19 | 7419.0 |
| RPS3 | 7411.0 |
| RPL41 | 7335.0 |
| RPL6 | 7304.0 |
| RPS27A | 7120.0 |
| EIF4H | 6954.0 |
| RPL23 | 6935.0 |
| FAU | 6424.0 |
| RPL11 | 6414.0 |
| RPL21 | 6341.0 |
| RPL13 | 6125.0 |
| RPS26 | 6058.0 |
| RPL7A | 5991.0 |
| RPS16 | 5896.0 |
| RPL8 | 5822.0 |
| RPS7 | 5716.0 |
| EIF4EBP1 | 5542.0 |
| RPL26L1 | 5531.0 |
| EIF5B | 5527.0 |
| RPS8 | 5431.0 |
| EIF2B5 | 5319.0 |
| RPL37A | 5292.0 |
| RPL3L | 5206.0 |
| RPL13A | 5131.5 |
| RPS10 | 5058.0 |
| EIF2B3 | 4977.0 |
| RPL19 | 4913.0 |
| RPS18 | 4856.0 |
| RPL9 | 4760.0 |
| RPS27 | 4711.0 |
| RPS12 | 4501.0 |
| RPL35 | 4434.0 |
| RPL35A | 4218.0 |
| RPL17 | 4202.0 |
| RPSA | 3281.0 |
| RPL3 | 3240.0 |
| EIF4A2 | 3184.0 |
| RPL12 | 2822.0 |
| EIF2B2 | 2764.0 |
| RPS28 | 2669.0 |
| EIF2S1 | 2623.0 |
| RPL27A | 2494.0 |
| RPL15 | 2382.0 |
| RPL32 | 2362.0 |
| RPS15A | 2095.0 |
| EIF2S2 | 2093.0 |
| RPS25 | 1988.0 |
| RPLP1 | 1762.0 |
| EIF4G1 | 1551.0 |
| RPL7 | 1442.0 |
| EIF2B4 | 1214.0 |
| EIF3H | 170.0 |
| RPL5 | -139.0 |
| EIF3B | -862.0 |
| RPS2 | -1028.0 |
| RPS14 | -1691.0 |
| RPL30 | -2061.0 |
| RPS5 | -2579.0 |
| RPS6 | -2673.0 |
| RPL39L | -3132.0 |
| RPL37 | -3282.0 |
| EIF4B | -3542.0 |
| UBA52 | -3755.0 |
| RPS15 | -4150.0 |
| EIF5 | -4490.0 |
| RPL24 | -4644.0 |
| RPS9 | -4650.0 |
| EIF3G | -5119.0 |
| RPL4 | -5128.0 |
| RPL27 | -5306.0 |
| RPL18A | -5425.0 |
| RPL22 | -5765.0 |
| RPLP2 | -5777.0 |
| RPS27L | -5945.0 |
| EIF3L | -5990.0 |
| EIF3M | -7387.0 |
| EIF3I | -7728.0 |
| EIF3A | -7810.0 |
| RPL36 | -8155.0 |
| RPS11 | -8626.0 |
| RPL10L | -10090.0 |
REACTOME_CELL_CYCLE_CHECKPOINTS
| 1120 | |
|---|---|
| set | REACTOME_CELL_CYCLE_CHECKPOINTS |
| setSize | 284 |
| pANOVA | 6.48e-07 |
| s.dist | 0.172 |
| p.adjustANOVA | 9.68e-05 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| H4C8 | 10752 |
| CENPQ | 10378 |
| PSMD12 | 10325 |
| DYNC1LI2 | 10216 |
| PSMC6 | 9977 |
| KNTC1 | 9932 |
| PSMB3 | 9858 |
| UBC | 9476 |
| DSN1 | 9391 |
| MCM2 | 9367 |
| BABAM1 | 9283 |
| RAD1 | 9237 |
| KAT5 | 9221 |
| MCM10 | 9189 |
| PPP2R5B | 9055 |
| ZWINT | 8928 |
| H4C12 | 8883 |
| BUB1B | 8870 |
| AURKB | 8795 |
| PPP2R5D | 8711 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| H4C8 | 10752.0 |
| CENPQ | 10378.0 |
| PSMD12 | 10325.0 |
| DYNC1LI2 | 10216.0 |
| PSMC6 | 9977.0 |
| KNTC1 | 9932.0 |
| PSMB3 | 9858.0 |
| UBC | 9476.0 |
| DSN1 | 9391.0 |
| MCM2 | 9367.0 |
| BABAM1 | 9283.0 |
| RAD1 | 9237.0 |
| KAT5 | 9221.0 |
| MCM10 | 9189.0 |
| PPP2R5B | 9055.0 |
| ZWINT | 8928.0 |
| H4C12 | 8883.0 |
| BUB1B | 8870.0 |
| AURKB | 8795.0 |
| PPP2R5D | 8711.0 |
| ITGB3BP | 8707.0 |
| H4C2 | 8690.0 |
| PSME2 | 8685.0 |
| BARD1 | 8638.0 |
| H2BC13 | 8609.0 |
| MDM4 | 8496.0 |
| CDKN1B | 8453.0 |
| H2BC1 | 8383.0 |
| CLIP1 | 8357.0 |
| DYNLL2 | 8325.0 |
| DNA2 | 8298.0 |
| PSMB4 | 8180.0 |
| TP53 | 8108.0 |
| CDC45 | 7992.0 |
| PSMD13 | 7901.0 |
| RBBP8 | 7822.0 |
| H2BC7 | 7754.5 |
| CENPM | 7709.0 |
| PSME4 | 7705.0 |
| CENPL | 7683.0 |
| UBB | 7674.0 |
| PSMB2 | 7641.0 |
| NDC80 | 7594.0 |
| CDC25A | 7593.0 |
| AHCTF1 | 7417.0 |
| CCNB1 | 7396.0 |
| ABRAXAS1 | 7372.0 |
| PSMB11 | 7359.0 |
| CDKN2A | 7282.0 |
| H4C16 | 7260.0 |
| PSMA6 | 7190.0 |
| BIRC5 | 7158.0 |
| RPS27A | 7120.0 |
| CDC25C | 7020.0 |
| PSMA1 | 7018.0 |
| ANAPC11 | 6955.0 |
| CDK2 | 6939.0 |
| CHEK1 | 6909.0 |
| SEH1L | 6838.0 |
| ORC1 | 6803.0 |
| BUB1 | 6792.0 |
| NUP85 | 6688.0 |
| PSMD3 | 6672.0 |
| MDC1 | 6671.0 |
| RHNO1 | 6649.0 |
| RAD9A | 6635.0 |
| CENPC | 6615.0 |
| MCM5 | 6536.0 |
| NUP37 | 6306.0 |
| RNF8 | 6146.0 |
| ZW10 | 6123.0 |
| H2BC8 | 6087.0 |
| SKA2 | 6014.0 |
| H4C3 | 5935.0 |
| NUP43 | 5921.0 |
| YWHAB | 5879.0 |
| KNL1 | 5868.0 |
| ANAPC10 | 5865.0 |
| H4C1 | 5864.0 |
| CKAP5 | 5856.0 |
| B9D2 | 5784.0 |
| CENPT | 5768.0 |
| PSMC1 | 5715.0 |
| MCM4 | 5708.0 |
| SGO2 | 5675.0 |
| RPA1 | 5651.0 |
| PSMD2 | 5624.0 |
| MRE11 | 5620.0 |
| PAFAH1B1 | 5441.0 |
| PSMA5 | 5362.0 |
| PLK1 | 5347.0 |
| ANAPC2 | 5346.0 |
| KIF2C | 5265.0 |
| DBF4 | 5250.0 |
| PSMA4 | 5246.0 |
| PSMC5 | 5193.0 |
| H2BC5 | 5130.0 |
| NUP107 | 5069.0 |
| CDKN1A | 5054.0 |
| H4C6 | 4952.0 |
| RCC2 | 4920.0 |
| MCM3 | 4832.0 |
| CDC20 | 4753.0 |
| RPS27 | 4711.0 |
| SPC25 | 4707.0 |
| NUP133 | 4676.0 |
| ANAPC5 | 4671.0 |
| H2BC3 | 4658.0 |
| YWHAZ | 4655.0 |
| H4C13 | 4630.0 |
| BRIP1 | 4606.0 |
| ATM | 4600.0 |
| ORC2 | 4592.0 |
| H4C11 | 4553.0 |
| KIF18A | 4448.0 |
| MAD2L1 | 4439.0 |
| NSL1 | 4358.0 |
| PSMF1 | 4311.0 |
| BLM | 4237.0 |
| PMF1 | 4232.0 |
| PSMD1 | 4227.0 |
| PSME3 | 4172.0 |
| CENPE | 4143.0 |
| PSMC2 | 4088.0 |
| CENPS | 4026.0 |
| CDCA8 | 3983.0 |
| H2BC10 | 3947.0 |
| PSMA8 | 3923.0 |
| PSMA7 | 3903.0 |
| PSME1 | 3866.0 |
| PSMA3 | 3850.0 |
| H4C4 | 3785.0 |
| MAPRE1 | 3644.0 |
| EXO1 | 3595.0 |
| CCNA1 | 3593.0 |
| PSMB9 | 3459.0 |
| CHEK2 | 3413.0 |
| PPP2R5C | 3398.0 |
| HUS1 | 3387.0 |
| H2BC17 | 3276.0 |
| CENPF | 3253.0 |
| CCNE2 | 3190.0 |
| RFC2 | 3136.0 |
| CDC27 | 3049.0 |
| PSMC4 | 3004.0 |
| NUF2 | 2983.0 |
| PSMC3 | 2960.0 |
| MCM7 | 2717.0 |
| YWHAH | 2697.0 |
| RANBP2 | 2651.0 |
| SEM1 | 2517.0 |
| UBE2N | 2342.0 |
| CDC26 | 2306.0 |
| PPP2CA | 2292.0 |
| MCM8 | 2177.0 |
| CCNB2 | 2043.0 |
| H3-4 | 2030.0 |
| ORC4 | 1976.0 |
| ANAPC15 | 1950.0 |
| CDC23 | 1927.0 |
| BUB3 | 1906.0 |
| SGO1 | 1729.0 |
| CENPK | 1710.0 |
| CDC7 | 1479.0 |
| H2BC11 | 1338.0 |
| BRCA1 | 1120.0 |
| RPA2 | 1117.0 |
| RFC4 | 824.0 |
| CDC16 | 754.0 |
| YWHAE | 744.0 |
| NDEL1 | 641.0 |
| PSMD11 | 620.0 |
| H2AX | 499.0 |
| PCBP4 | 475.0 |
| PSMB8 | 447.0 |
| YWHAQ | 336.0 |
| RAD17 | 283.0 |
| TOP3A | 244.0 |
| H2BC15 | 240.0 |
| DYNC1LI1 | 233.0 |
| MDM2 | 219.0 |
| UIMC1 | 46.0 |
| RAD9B | 45.0 |
| ORC3 | 36.0 |
| MIS12 | 15.0 |
| MCM6 | 2.0 |
| RFC5 | -81.0 |
| PSMA2 | -85.0 |
| PPP2R5A | -152.0 |
| DYNC1I1 | -202.0 |
| NSD2 | -277.0 |
| ANAPC4 | -310.0 |
| RMI1 | -315.0 |
| NUP98 | -351.0 |
| DYNC1I2 | -440.0 |
| UBE2V2 | -500.0 |
| COP1 | -554.0 |
| ORC5 | -617.0 |
| PSMD14 | -865.0 |
| CENPO | -914.0 |
| PSMD6 | -961.0 |
| SPDL1 | -977.0 |
| ANAPC1 | -1043.0 |
| XPO1 | -1083.0 |
| PSMB7 | -1294.0 |
| UBE2S | -1361.0 |
| H2BC6 | -1396.0 |
| NUDC | -1567.0 |
| YWHAG | -1887.0 |
| PHF20 | -1999.0 |
| CLASP1 | -2048.0 |
| H2BC4 | -2094.0 |
| PPP2R1A | -2107.0 |
| H2BC12 | -2115.0 |
| CENPN | -2163.0 |
| CLASP2 | -2170.0 |
| TP53BP1 | -2175.0 |
| ZWILCH | -2190.0 |
| PSMB10 | -2290.0 |
| PSMB6 | -2408.0 |
| PPP2R5E | -2509.0 |
| UBE2C | -2539.0 |
| PIAS4 | -2542.0 |
| PSMD9 | -2570.0 |
| UBE2E1 | -2647.0 |
| CLSPN | -2700.0 |
| WRN | -2909.0 |
| HERC2 | -3058.0 |
| PPP1CC | -3102.0 |
| WEE1 | -3415.0 |
| SPC24 | -3429.0 |
| ORC6 | -3467.0 |
| CCNA2 | -3495.0 |
| DYNLL1 | -3541.0 |
| GTSE1 | -3549.0 |
| RMI2 | -3754.0 |
| UBA52 | -3755.0 |
| PKMYT1 | -3762.0 |
| ANAPC7 | -3780.0 |
| NBN | -3893.0 |
| RANGAP1 | -3961.0 |
| ANAPC16 | -4502.0 |
| ATR | -4506.0 |
| PSMB5 | -4687.0 |
| H2BC9 | -4907.5 |
| H4C5 | -4941.0 |
| RFC3 | -4967.0 |
| PSMD7 | -5198.0 |
| ATRIP | -5201.0 |
| RNF168 | -5219.0 |
| TAOK1 | -5237.0 |
| INCENP | -5274.0 |
| PSMD4 | -5337.0 |
| UBE2D1 | -5394.0 |
| SEC13 | -5670.0 |
| H2BC21 | -5773.0 |
| TOPBP1 | -5800.0 |
| NDE1 | -5839.0 |
| PSMB1 | -5858.0 |
| MAD1L1 | -6006.0 |
| DYNC1H1 | -6092.0 |
| BABAM2 | -6094.0 |
| CDK1 | -6160.0 |
| CENPU | -6349.0 |
| RAD50 | -6431.0 |
| H2BC26 | -6695.0 |
| SKA1 | -6910.0 |
| KIF2A | -6979.0 |
| NUP160 | -7169.0 |
| PPP2CB | -7216.0 |
| CDC6 | -7443.0 |
| PSMD8 | -7723.0 |
| CENPP | -7911.0 |
| RPA3 | -8086.0 |
| ZNF385A | -8149.0 |
| PPP2R1B | -8245.0 |
| CENPH | -8704.0 |
| H2BC14 | -8730.0 |
| KIF2B | -8857.0 |
| H4C9 | -9282.0 |
| SFN | -9368.0 |
| PSMD5 | -9524.0 |
| CCNE1 | -9930.0 |
| CENPA | -9945.0 |
REACTOME_SIGNALING_BY_ROBO_RECEPTORS
| 605 | |
|---|---|
| set | REACTOME_SIGNALING_BY_ROBO_RECEPTORS |
| setSize | 206 |
| pANOVA | 7.56e-07 |
| s.dist | 0.2 |
| p.adjustANOVA | 0.000102 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| ELOB | 10991 |
| PSMD12 | 10325 |
| RPL14 | 10215 |
| RPL18 | 10082 |
| RPL10A | 10035 |
| CXCR4 | 9979 |
| PSMC6 | 9977 |
| PSMB3 | 9858 |
| RPL23A | 9830 |
| RPS13 | 9737 |
| RBM8A | 9578 |
| UBC | 9476 |
| RPL38 | 9474 |
| ELOC | 9413 |
| RBX1 | 9293 |
| RPS21 | 9255 |
| RPLP0 | 9213 |
| RPL29 | 9165 |
| RPS3A | 8946 |
| LDB1 | 8879 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ELOB | 10991.0 |
| PSMD12 | 10325.0 |
| RPL14 | 10215.0 |
| RPL18 | 10082.0 |
| RPL10A | 10035.0 |
| CXCR4 | 9979.0 |
| PSMC6 | 9977.0 |
| PSMB3 | 9858.0 |
| RPL23A | 9830.0 |
| RPS13 | 9737.0 |
| RBM8A | 9578.0 |
| UBC | 9476.0 |
| RPL38 | 9474.0 |
| ELOC | 9413.0 |
| RBX1 | 9293.0 |
| RPS21 | 9255.0 |
| RPLP0 | 9213.0 |
| RPL29 | 9165.0 |
| RPS3A | 8946.0 |
| LDB1 | 8879.0 |
| RPL28 | 8875.0 |
| PSME2 | 8685.0 |
| DAG1 | 8634.0 |
| ROBO3 | 8567.0 |
| PABPC1 | 8543.0 |
| FLRT3 | 8478.0 |
| RPL36AL | 8459.5 |
| RPL22L1 | 8449.0 |
| RPL31 | 8273.0 |
| PSMB4 | 8180.0 |
| RPS24 | 8170.0 |
| PRKACG | 8167.0 |
| RPS23 | 8094.0 |
| RPL26 | 8016.0 |
| LHX3 | 8002.0 |
| RPS20 | 7907.0 |
| PSMD13 | 7901.0 |
| UPF2 | 7759.0 |
| VASP | 7707.0 |
| PSME4 | 7705.0 |
| UBB | 7674.0 |
| PSMB2 | 7641.0 |
| RPS29 | 7621.0 |
| RPL34 | 7423.0 |
| RPS19 | 7419.0 |
| RPS3 | 7411.0 |
| PSMB11 | 7359.0 |
| RPL41 | 7335.0 |
| RPL6 | 7304.0 |
| PSMA6 | 7190.0 |
| RPS27A | 7120.0 |
| PSMA1 | 7018.0 |
| RPL23 | 6935.0 |
| LHX9 | 6785.0 |
| PSMD3 | 6672.0 |
| ABL2 | 6455.0 |
| FAU | 6424.0 |
| EIF4A3 | 6420.0 |
| RPL11 | 6414.0 |
| RPL21 | 6341.0 |
| NCK1 | 6286.0 |
| RPL13 | 6125.0 |
| RPS26 | 6058.0 |
| RPL7A | 5991.0 |
| RPS16 | 5896.0 |
| RPL8 | 5822.0 |
| EVL | 5795.0 |
| RPS7 | 5716.0 |
| PSMC1 | 5715.0 |
| NCBP1 | 5705.0 |
| PSMD2 | 5624.0 |
| RPL26L1 | 5531.0 |
| RPS8 | 5431.0 |
| USP33 | 5423.0 |
| PSMA5 | 5362.0 |
| RPL37A | 5292.0 |
| PSMA4 | 5246.0 |
| RPL3L | 5206.0 |
| PSMC5 | 5193.0 |
| RPL13A | 5131.5 |
| RPS10 | 5058.0 |
| LHX4 | 4938.0 |
| RPL19 | 4913.0 |
| RPS18 | 4856.0 |
| RPL9 | 4760.0 |
| RPS27 | 4711.0 |
| CAP1 | 4706.0 |
| LHX2 | 4613.0 |
| RNPS1 | 4528.0 |
| RPS12 | 4501.0 |
| ISL1 | 4475.0 |
| RPL35 | 4434.0 |
| PSMF1 | 4311.0 |
| PSMD1 | 4227.0 |
| RPL35A | 4218.0 |
| RPL17 | 4202.0 |
| PSME3 | 4172.0 |
| NRP1 | 4148.0 |
| PSMC2 | 4088.0 |
| CASC3 | 4044.0 |
| PSMA8 | 3923.0 |
| PSMA7 | 3903.0 |
| PSME1 | 3866.0 |
| PSMA3 | 3850.0 |
| CDC42 | 3714.0 |
| SOS1 | 3578.0 |
| PRKACA | 3519.0 |
| PSMB9 | 3459.0 |
| RPSA | 3281.0 |
| RPL3 | 3240.0 |
| PSMC4 | 3004.0 |
| PSMC3 | 2960.0 |
| MSI1 | 2848.0 |
| RPL12 | 2822.0 |
| MYO9B | 2714.0 |
| RPS28 | 2669.0 |
| SEM1 | 2517.0 |
| RPL27A | 2494.0 |
| PAK2 | 2407.0 |
| RPL15 | 2382.0 |
| RPL32 | 2362.0 |
| RPS15A | 2095.0 |
| RPS25 | 1988.0 |
| RPLP1 | 1762.0 |
| EIF4G1 | 1551.0 |
| RPL7 | 1442.0 |
| PRKACB | 1268.0 |
| DCC | 1172.0 |
| ENAH | 1062.0 |
| CAP2 | 874.0 |
| PAK5 | 746.0 |
| PSMD11 | 620.0 |
| SRGAP2 | 616.0 |
| PSMB8 | 447.0 |
| NCK2 | 63.0 |
| PSMA2 | -85.0 |
| RPL5 | -139.0 |
| PAK6 | -713.0 |
| PSMD14 | -865.0 |
| PSMD6 | -961.0 |
| RPS2 | -1028.0 |
| PFN1 | -1250.0 |
| PSMB7 | -1294.0 |
| RPS14 | -1691.0 |
| MAGOHB | -1800.0 |
| SOS2 | -1920.0 |
| CLASP1 | -2048.0 |
| RPL30 | -2061.0 |
| CUL2 | -2081.0 |
| CLASP2 | -2170.0 |
| PSMB10 | -2290.0 |
| PSMB6 | -2408.0 |
| NELL2 | -2428.0 |
| GSPT1 | -2497.0 |
| RAC1 | -2500.0 |
| PSMD9 | -2570.0 |
| ETF1 | -2575.0 |
| RPS5 | -2579.0 |
| PRKAR2A | -2605.0 |
| RPS6 | -2673.0 |
| RPL39L | -3132.0 |
| GPC1 | -3133.0 |
| NCBP2 | -3139.0 |
| PRKCA | -3175.0 |
| RPL37 | -3282.0 |
| SRGAP3 | -3512.0 |
| ROBO2 | -3642.0 |
| UBA52 | -3755.0 |
| ARHGAP39 | -3844.0 |
| AKAP5 | -4145.0 |
| RPS15 | -4150.0 |
| SRC | -4161.0 |
| SLIT2 | -4401.0 |
| PAK4 | -4423.0 |
| RPL24 | -4644.0 |
| RPS9 | -4650.0 |
| PSMB5 | -4687.0 |
| PAK1 | -4897.0 |
| CXCL12 | -4990.0 |
| RPL4 | -5128.0 |
| PSMD7 | -5198.0 |
| SLIT1 | -5260.0 |
| RHOA | -5289.0 |
| RPL27 | -5306.0 |
| HOXA2 | -5327.0 |
| PSMD4 | -5337.0 |
| RPL18A | -5425.0 |
| RPL22 | -5765.0 |
| RPLP2 | -5777.0 |
| PSMB1 | -5858.0 |
| ROBO1 | -5895.0 |
| RPS27L | -5945.0 |
| PFN2 | -6601.0 |
| NTN1 | -6703.0 |
| SRGAP1 | -7054.0 |
| ZSWIM8 | -7205.0 |
| PPP3CB | -7407.0 |
| SLIT3 | -7500.0 |
| PSMD8 | -7723.0 |
| UPF3A | -7770.0 |
| RPL36 | -8155.0 |
| ABL1 | -8289.0 |
| RPS11 | -8626.0 |
| MAGOH | -9309.0 |
| PSMD5 | -9524.0 |
| RPL10L | -10090.0 |
REACTOME_INFECTIOUS_DISEASE
| 974 | |
|---|---|
| set | REACTOME_INFECTIOUS_DISEASE |
| setSize | 910 |
| pANOVA | 8.06e-07 |
| s.dist | 0.0964 |
| p.adjustANOVA | 0.000102 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| IFNA13 | 11049 |
| ELOB | 10991 |
| IFNA1 | 10960 |
| H4C8 | 10752 |
| FXYD7 | 10698 |
| TAF7 | 10601 |
| GNG13 | 10553 |
| GNG8 | 10427 |
| CHMP5 | 10418 |
| FGR | 10409 |
| POLR2K | 10402 |
| CHMP4C | 10392 |
| PTPN11 | 10353 |
| DPEP2 | 10347 |
| PSMD12 | 10325 |
| RNF135 | 10242 |
| DYNC1LI2 | 10216 |
| RPL14 | 10215 |
| SUZ12 | 10134 |
| RPL18 | 10082 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IFNA13 | 11049.0 |
| ELOB | 10991.0 |
| IFNA1 | 10960.0 |
| H4C8 | 10752.0 |
| FXYD7 | 10698.0 |
| TAF7 | 10601.0 |
| GNG13 | 10553.0 |
| GNG8 | 10427.0 |
| CHMP5 | 10418.0 |
| FGR | 10409.0 |
| POLR2K | 10402.0 |
| CHMP4C | 10392.0 |
| PTPN11 | 10353.0 |
| DPEP2 | 10347.0 |
| PSMD12 | 10325.0 |
| RNF135 | 10242.0 |
| DYNC1LI2 | 10216.0 |
| RPL14 | 10215.0 |
| SUZ12 | 10134.0 |
| RPL18 | 10082.0 |
| RPL10A | 10035.0 |
| BANF1 | 10027.0 |
| TAF6 | 10014.0 |
| CXCR4 | 9979.0 |
| ACTG1 | 9978.0 |
| PSMC6 | 9977.0 |
| CRB3 | 9930.0 |
| PYCARD | 9904.0 |
| VPS37B | 9890.0 |
| PSMB3 | 9858.0 |
| TLR2 | 9837.0 |
| RPL23A | 9830.0 |
| TLR9 | 9810.0 |
| IFNGR2 | 9768.0 |
| RPS13 | 9737.0 |
| ACTB | 9643.0 |
| JUN | 9609.0 |
| GNG10 | 9574.0 |
| H2AC11 | 9543.0 |
| VPS33B | 9535.0 |
| AP1M2 | 9525.0 |
| VAV1 | 9507.0 |
| SFTPD | 9481.0 |
| UBC | 9476.0 |
| RPL38 | 9474.0 |
| UBE2V1 | 9459.0 |
| ELOC | 9413.0 |
| AP1S3 | 9359.0 |
| WASF1 | 9310.0 |
| RBX1 | 9293.0 |
| RPS21 | 9255.0 |
| HAVCR1 | 9225.0 |
| IL6 | 9220.0 |
| RPLP0 | 9213.0 |
| DDOST | 9201.0 |
| HMG20B | 9194.0 |
| IFNAR1 | 9173.0 |
| RPL29 | 9165.0 |
| NLRP12 | 9135.0 |
| DDX20 | 9118.0 |
| TLR1 | 9115.0 |
| LCK | 9065.0 |
| TUBB6 | 9058.0 |
| H3C10 | 9015.0 |
| FEN1 | 9002.0 |
| SYK | 8993.0 |
| ATG14 | 8971.0 |
| TXN | 8969.0 |
| H3C11 | 8963.0 |
| HNRNPA1 | 8950.0 |
| RPS3A | 8946.0 |
| POM121 | 8943.0 |
| VPS18 | 8931.0 |
| ISG15 | 8922.0 |
| H4C12 | 8883.0 |
| RPL28 | 8875.0 |
| ISCU | 8763.0 |
| TAF15 | 8749.0 |
| HLA-G | 8743.0 |
| MAPK14 | 8739.0 |
| SAP18 | 8722.0 |
| H4C2 | 8690.0 |
| PSME2 | 8685.0 |
| H2AC12 | 8679.0 |
| WASF2 | 8672.0 |
| VPS33A | 8662.0 |
| LYN | 8661.0 |
| H2BC13 | 8609.0 |
| PPIB | 8591.0 |
| MGAT2 | 8459.5 |
| RPL36AL | 8459.5 |
| GNB2 | 8457.0 |
| RPL22L1 | 8449.0 |
| TGFB1 | 8436.0 |
| CCNH | 8435.0 |
| H2BC1 | 8383.0 |
| TAF13 | 8377.0 |
| TUBAL3 | 8355.0 |
| DYNLL2 | 8325.0 |
| PDCD1 | 8323.0 |
| CANX | 8307.0 |
| RPL31 | 8273.0 |
| GATAD2B | 8270.0 |
| TAF10 | 8254.0 |
| CCR5 | 8206.0 |
| PARP1 | 8191.0 |
| PSMB4 | 8180.0 |
| RPS24 | 8170.0 |
| PRKACG | 8167.0 |
| GRB2 | 8138.0 |
| VPS39 | 8130.0 |
| SMAD4 | 8113.0 |
| NOXO1 | 8106.0 |
| RPS23 | 8094.0 |
| PTPN6 | 8069.0 |
| H3C12 | 8052.0 |
| JAK1 | 8034.0 |
| RPL26 | 8016.0 |
| TUBB4B | 7956.0 |
| POLR2I | 7943.0 |
| ARPC3 | 7914.0 |
| RPS20 | 7907.0 |
| PSMD13 | 7901.0 |
| RPN1 | 7882.0 |
| TXNIP | 7855.0 |
| CD79B | 7844.0 |
| ENTPD5 | 7779.0 |
| TUBB3 | 7767.0 |
| NUP155 | 7761.0 |
| H2AC7 | 7754.5 |
| H2BC7 | 7754.5 |
| PSME4 | 7705.0 |
| MAP2K3 | 7685.0 |
| UBB | 7674.0 |
| IFNGR1 | 7666.0 |
| ANO8 | 7645.0 |
| PSMB2 | 7641.0 |
| RPS29 | 7621.0 |
| IL18 | 7601.0 |
| CD79A | 7596.0 |
| NOXA1 | 7589.0 |
| GEMIN6 | 7578.0 |
| GOLGA7 | 7563.0 |
| ERCC2 | 7510.0 |
| GNB1 | 7509.0 |
| VEGFA | 7485.0 |
| TRIM28 | 7470.0 |
| WIPF2 | 7436.0 |
| H2AC16 | 7429.0 |
| RPL34 | 7423.0 |
| RPS19 | 7419.0 |
| RPS3 | 7411.0 |
| GNAI2 | 7402.0 |
| TAF1L | 7369.0 |
| PSMB11 | 7359.0 |
| ZCRB1 | 7357.0 |
| NMT2 | 7350.0 |
| RPL41 | 7335.0 |
| KDM1A | 7329.0 |
| ZDHHC8 | 7322.0 |
| RPL6 | 7304.0 |
| IFNA7 | 7302.0 |
| HBEGF | 7288.0 |
| B2M | 7278.0 |
| ZDHHC2 | 7273.0 |
| H4C16 | 7260.0 |
| TUBA8 | 7215.0 |
| PSMA6 | 7190.0 |
| SFPQ | 7149.0 |
| NCKAP1L | 7142.0 |
| PARP8 | 7139.0 |
| WNT5A | 7135.0 |
| RPS27A | 7120.0 |
| GTF2H1 | 7100.0 |
| STAT2 | 7075.0 |
| SLC25A4 | 7067.0 |
| H2AC1 | 7060.0 |
| PPIH | 7024.0 |
| PSMA1 | 7018.0 |
| GATAD2A | 7005.0 |
| NLRP3 | 7003.0 |
| TOMM70 | 6987.0 |
| VAMP1 | 6971.0 |
| CALR | 6943.0 |
| RPL23 | 6935.0 |
| MGAT1 | 6924.0 |
| ARPC1B | 6892.0 |
| NPM1 | 6858.0 |
| RBBP4 | 6844.0 |
| SEH1L | 6838.0 |
| ENTPD1 | 6837.0 |
| NUP35 | 6822.0 |
| TUBB8 | 6817.0 |
| SUPT16H | 6796.0 |
| TUBB2B | 6768.0 |
| BRMS1 | 6753.0 |
| NUP85 | 6688.0 |
| PSMD3 | 6672.0 |
| H2AC8 | 6630.0 |
| ST6GALNAC2 | 6620.0 |
| CORO1A | 6598.0 |
| LIG4 | 6572.0 |
| MAP2K7 | 6542.0 |
| CYSLTR2 | 6529.0 |
| HCK | 6499.0 |
| SIGMAR1 | 6494.0 |
| FAU | 6424.0 |
| RPL11 | 6414.0 |
| GNB5 | 6369.0 |
| BECN1 | 6352.0 |
| RPL21 | 6341.0 |
| NR3C1 | 6322.0 |
| CD3G | 6321.0 |
| CHD4 | 6316.0 |
| NUP37 | 6306.0 |
| EDEM2 | 6290.0 |
| NCK1 | 6286.0 |
| NMI | 6249.0 |
| FZD7 | 6194.0 |
| IFNA14 | 6151.0 |
| GNG2 | 6135.0 |
| RPL13 | 6125.0 |
| H2BC8 | 6087.0 |
| DDX5 | 6081.0 |
| IKBKE | 6071.0 |
| IFNA2 | 6068.0 |
| RPS26 | 6058.0 |
| TCEA1 | 6057.0 |
| CREB1 | 6047.0 |
| RPL7A | 5991.0 |
| GTF2H3 | 5990.0 |
| ST3GAL1 | 5972.0 |
| CYBA | 5941.0 |
| H4C3 | 5935.0 |
| NUP43 | 5921.0 |
| IFNAR2 | 5911.0 |
| ATP1B2 | 5900.0 |
| H2AC17 | 5897.0 |
| RPS16 | 5896.0 |
| YWHAB | 5879.0 |
| H4C1 | 5864.0 |
| GEMIN4 | 5843.0 |
| RPL8 | 5822.0 |
| SV2B | 5808.0 |
| SDC3 | 5772.0 |
| RB1 | 5745.0 |
| RPS7 | 5716.0 |
| PSMC1 | 5715.0 |
| IRAK2 | 5710.0 |
| NCBP1 | 5705.0 |
| RAN | 5697.0 |
| FKBP1A | 5684.0 |
| IRF3 | 5649.0 |
| NUP54 | 5644.0 |
| PSMD2 | 5624.0 |
| H3C1 | 5598.0 |
| RPL26L1 | 5531.0 |
| CHUK | 5500.0 |
| PABPN1 | 5490.0 |
| BCL2L1 | 5479.0 |
| RCOR1 | 5446.0 |
| NFKBIA | 5436.0 |
| RPS8 | 5431.0 |
| IFNA8 | 5410.0 |
| MGAT4B | 5400.0 |
| MYO1C | 5390.0 |
| HLA-E | 5384.0 |
| CEBPD | 5373.0 |
| IFNA16 | 5367.0 |
| PSMA5 | 5362.0 |
| CLTC | 5328.0 |
| HDAC2 | 5322.0 |
| MVB12A | 5316.0 |
| RPL37A | 5292.0 |
| SV2C | 5263.0 |
| PSMA4 | 5246.0 |
| SNRPF | 5221.0 |
| RPL3L | 5206.0 |
| PSMC5 | 5193.0 |
| SNRPD2 | 5177.0 |
| CNBP | 5171.0 |
| RPL13A | 5131.5 |
| H2BC5 | 5130.0 |
| CD28 | 5116.0 |
| IMPDH2 | 5096.0 |
| VPS45 | 5070.0 |
| NUP107 | 5069.0 |
| RPS10 | 5058.0 |
| SH3GL1 | 5047.0 |
| TAF11 | 5030.0 |
| CUL5 | 5014.0 |
| CCNT2 | 5011.0 |
| DAXX | 4994.0 |
| ST6GALNAC4 | 4953.0 |
| H4C6 | 4952.0 |
| AP2B1 | 4937.0 |
| RPL19 | 4913.0 |
| BLNK | 4880.0 |
| RPS18 | 4856.0 |
| MYH9 | 4847.0 |
| ZDHHC5 | 4843.0 |
| GUCY2C | 4808.0 |
| VAMP2 | 4802.0 |
| NUP88 | 4788.0 |
| RPL9 | 4760.0 |
| H3C4 | 4718.0 |
| RPS27 | 4711.0 |
| CBX1 | 4709.0 |
| ITGA4 | 4701.0 |
| SNAP25 | 4681.0 |
| NUP133 | 4676.0 |
| AP1M1 | 4662.0 |
| H2BC3 | 4658.0 |
| YWHAZ | 4655.0 |
| ARID4B | 4651.0 |
| SMN1 | 4648.5 |
| SMN2 | 4648.5 |
| GSK3A | 4632.0 |
| H4C13 | 4630.0 |
| ADORA2B | 4622.0 |
| XRCC6 | 4619.0 |
| SSRP1 | 4571.0 |
| H4C11 | 4553.0 |
| STAM2 | 4533.0 |
| NELFE | 4505.0 |
| RPS12 | 4501.0 |
| PCBP2 | 4487.0 |
| DVL1 | 4458.0 |
| FYN | 4444.0 |
| RPL35 | 4434.0 |
| KPNB1 | 4376.0 |
| PSMF1 | 4311.0 |
| ATP1A1 | 4284.0 |
| UBE2I | 4265.0 |
| CTDP1 | 4247.0 |
| PTGES3 | 4234.0 |
| PSMD1 | 4227.0 |
| GNAI3 | 4219.0 |
| RPL35A | 4218.0 |
| RPL17 | 4202.0 |
| APP | 4173.0 |
| PSME3 | 4172.0 |
| NRP1 | 4148.0 |
| MBD3 | 4139.0 |
| PHF21A | 4131.0 |
| PSMC2 | 4088.0 |
| MAP1LC3B | 4080.0 |
| GNG5 | 3975.0 |
| H2BC10 | 3947.0 |
| PSMA8 | 3923.0 |
| CD163 | 3920.0 |
| POLR2A | 3916.0 |
| PSMA7 | 3903.0 |
| ATP1A2 | 3892.0 |
| DUSP16 | 3891.0 |
| PSME1 | 3866.0 |
| PSMA3 | 3850.0 |
| HSP90AB1 | 3811.0 |
| RHBDF2 | 3794.0 |
| AGRN | 3792.0 |
| H4C4 | 3785.0 |
| NELFCD | 3781.0 |
| NUP205 | 3738.0 |
| ARPC5 | 3724.0 |
| CDC42 | 3714.0 |
| MYO5A | 3683.0 |
| KPNA2 | 3680.0 |
| SOS1 | 3578.0 |
| SIKE1 | 3566.0 |
| GTF2E1 | 3557.0 |
| SKP1 | 3534.0 |
| ANO6 | 3532.0 |
| PRKACA | 3519.0 |
| G3BP2 | 3501.0 |
| ST6GAL1 | 3463.0 |
| PSMB9 | 3459.0 |
| SNRPG | 3425.0 |
| RCC1 | 3406.0 |
| ELMO1 | 3405.0 |
| ARPC4 | 3357.0 |
| RCAN3 | 3337.0 |
| C3AR1 | 3335.0 |
| STING1 | 3310.0 |
| KPNA1 | 3308.0 |
| RPSA | 3281.0 |
| ZDHHC3 | 3277.0 |
| H2BC17 | 3276.0 |
| KPNA7 | 3260.0 |
| RPL3 | 3240.0 |
| PRKAR1A | 3239.0 |
| TAF5 | 3203.0 |
| AP2S1 | 3202.0 |
| POLR2E | 3177.0 |
| CTSG | 3167.0 |
| PTK2 | 3128.0 |
| P2RX7 | 3074.0 |
| MASP1 | 3069.0 |
| H3C6 | 3009.0 |
| PSMC4 | 3004.0 |
| PSMC3 | 2960.0 |
| H2AC6 | 2946.0 |
| GTF2F2 | 2945.0 |
| GTF2A1 | 2934.0 |
| TUFM | 2923.0 |
| NUP42 | 2844.0 |
| RPL12 | 2822.0 |
| SV2A | 2817.0 |
| NUP93 | 2792.0 |
| ZDHHC11 | 2784.0 |
| MAP2K1 | 2768.0 |
| VPS37C | 2746.0 |
| MYO9B | 2714.0 |
| NUP58 | 2703.0 |
| H3C8 | 2699.0 |
| YWHAH | 2697.0 |
| RPS28 | 2669.0 |
| RANBP2 | 2651.0 |
| TAB1 | 2578.0 |
| SAP30L | 2545.0 |
| SEM1 | 2517.0 |
| RPL27A | 2494.0 |
| DAD1 | 2485.0 |
| ERCC3 | 2481.0 |
| VPS25 | 2434.0 |
| PAK2 | 2407.0 |
| UVRAG | 2384.0 |
| RPL15 | 2382.0 |
| H2AC4 | 2379.0 |
| RPL32 | 2362.0 |
| UBE2N | 2342.0 |
| ITCH | 2310.0 |
| PARP10 | 2273.0 |
| PRMT1 | 2256.0 |
| CHMP6 | 2240.0 |
| CHMP4A | 2193.0 |
| RAB5A | 2173.0 |
| KPNA5 | 2155.0 |
| NT5E | 2141.0 |
| ACTR3 | 2131.0 |
| RPS15A | 2095.0 |
| DNAJC3 | 2083.0 |
| ABI1 | 2081.0 |
| C3 | 2058.0 |
| POLR2D | 2025.0 |
| ADCY4 | 2002.0 |
| RPS25 | 1988.0 |
| ARID4A | 1923.0 |
| ST3GAL2 | 1867.0 |
| STT3A | 1866.0 |
| TXNRD1 | 1835.0 |
| RPLP1 | 1762.0 |
| HDAC3 | 1718.0 |
| IMPDH1 | 1715.0 |
| CHMP3 | 1707.0 |
| DVL3 | 1705.0 |
| MAVS | 1682.0 |
| SNRPD1 | 1669.0 |
| GNG11 | 1649.0 |
| MASP2 | 1631.0 |
| ITPR2 | 1625.0 |
| IL1A | 1611.0 |
| RNGTT | 1562.0 |
| RPL7 | 1442.0 |
| H3C2 | 1438.0 |
| TAF4B | 1414.0 |
| WIPF1 | 1400.0 |
| GNB4 | 1388.0 |
| GTF2H4 | 1369.0 |
| HSP90AA1 | 1355.0 |
| CHMP1A | 1351.0 |
| H2BC11 | 1338.0 |
| EIF2AK2 | 1335.0 |
| TBK1 | 1331.0 |
| HGS | 1315.0 |
| SNRPD3 | 1285.0 |
| PRKACB | 1268.0 |
| TAF9 | 1265.0 |
| VPS28 | 1219.0 |
| STX1A | 1212.0 |
| IFIH1 | 1116.0 |
| STAT1 | 1103.0 |
| SNRPE | 1082.0 |
| CCNK | 1079.0 |
| UBAP1 | 1070.0 |
| GPS2 | 1041.0 |
| PML | 1014.0 |
| XRCC4 | 999.0 |
| TUBA4A | 938.0 |
| VAV3 | 933.0 |
| AP2M1 | 907.0 |
| SAP30 | 893.0 |
| CCNT1 | 863.0 |
| ADCY2 | 862.0 |
| PACS1 | 769.0 |
| ENO1 | 763.0 |
| ADCY8 | 752.0 |
| YWHAE | 744.0 |
| PKLR | 742.0 |
| VHL | 735.0 |
| CBL | 728.0 |
| IKBKB | 710.0 |
| XRCC5 | 699.0 |
| ELOA | 667.0 |
| TUBA4B | 650.0 |
| PALS1 | 644.0 |
| ROCK1 | 627.0 |
| PSMD11 | 620.0 |
| EEF2 | 562.0 |
| HNRNPK | 537.0 |
| AP2A1 | 530.0 |
| H2AC13 | 492.0 |
| TRIM25 | 479.0 |
| IL6R | 467.0 |
| ANO10 | 466.0 |
| H2AC15 | 459.0 |
| CD9 | 454.0 |
| PSMB8 | 447.0 |
| HDAC1 | 346.0 |
| YWHAQ | 336.0 |
| CHMP7 | 308.0 |
| GEMIN7 | 272.0 |
| IL10 | 269.0 |
| CAV1 | 267.0 |
| H2BC15 | 240.0 |
| DYNC1LI1 | 233.0 |
| BTRC | 216.0 |
| GEMIN5 | 184.0 |
| ARPC2 | 177.0 |
| EED | 94.0 |
| LARP1 | -5.0 |
| ANO9 | -29.0 |
| MAN1B1 | -45.0 |
| SH3GL3 | -58.0 |
| PSMA2 | -85.0 |
| IPO5 | -110.0 |
| RPL5 | -139.0 |
| TAF12 | -160.0 |
| DYNC1I1 | -202.0 |
| TBP | -326.0 |
| NUP98 | -351.0 |
| NMT1 | -381.0 |
| NOS2 | -416.0 |
| DYNC1I2 | -440.0 |
| CHMP2A | -462.0 |
| NOD1 | -481.0 |
| HMGA1 | -496.0 |
| MEFV | -509.0 |
| H3C3 | -546.0 |
| SRPK2 | -567.0 |
| TUBB1 | -584.0 |
| GNG3 | -598.0 |
| PSTPIP1 | -629.0 |
| YES1 | -652.0 |
| H2AC20 | -674.0 |
| MNAT1 | -717.0 |
| ATP1A3 | -723.0 |
| RAB7A | -729.0 |
| GANAB | -732.0 |
| GALNT1 | -741.0 |
| AP1B1 | -856.0 |
| MAPK1 | -857.0 |
| FXYD2 | -858.0 |
| PSMD14 | -865.0 |
| VTA1 | -874.0 |
| GRSF1 | -941.0 |
| PSMD6 | -961.0 |
| POLR2L | -971.0 |
| SEC23A | -983.0 |
| BRK1 | -989.0 |
| RPS2 | -1028.0 |
| BAIAP2 | -1045.0 |
| XPO1 | -1083.0 |
| NFKB2 | -1089.0 |
| CHMP4B | -1102.0 |
| ZBP1 | -1155.0 |
| SNRPB | -1171.0 |
| PPIA | -1195.0 |
| CTNNB1 | -1232.0 |
| PSMB7 | -1294.0 |
| KPNA4 | -1299.0 |
| AP1S1 | -1310.0 |
| H2BC6 | -1396.0 |
| AHCYL1 | -1419.0 |
| NDC1 | -1433.0 |
| TBL1XR1 | -1440.0 |
| ADCY6 | -1477.0 |
| LIG1 | -1478.0 |
| IL17A | -1556.0 |
| EPS15 | -1611.0 |
| IL17F | -1612.0 |
| NOD2 | -1614.0 |
| CALM1 | -1622.0 |
| DOCK1 | -1627.0 |
| ARF1 | -1636.0 |
| ATP1B1 | -1661.0 |
| RPS14 | -1691.0 |
| MAP3K7 | -1717.0 |
| ELL | -1756.0 |
| ACTR2 | -1776.0 |
| RIPK2 | -1779.0 |
| PARP9 | -1825.0 |
| IL17RC | -1851.0 |
| NUP188 | -1877.0 |
| YWHAG | -1887.0 |
| GPC2 | -1956.0 |
| GNG7 | -1958.0 |
| ADAM17 | -1988.0 |
| MAP2K4 | -2008.0 |
| TRAF3 | -2012.0 |
| ATP6V1H | -2022.0 |
| MAP2K6 | -2038.0 |
| PDCD6IP | -2052.0 |
| S1PR1 | -2060.0 |
| RPL30 | -2061.0 |
| H2BC4 | -2094.0 |
| H2BC12 | -2115.0 |
| MVB12B | -2171.0 |
| ZDHHC20 | -2198.0 |
| VPS37A | -2207.0 |
| ANTXR1 | -2228.0 |
| TUBB | -2261.0 |
| PSMB10 | -2290.0 |
| CD8B | -2333.0 |
| GTF2H5 | -2337.0 |
| EP300 | -2354.0 |
| CYFIP2 | -2379.0 |
| GNAI1 | -2393.0 |
| PSMB6 | -2408.0 |
| CREBBP | -2409.0 |
| JAK2 | -2410.0 |
| EZH2 | -2415.0 |
| FXYD4 | -2478.0 |
| AKT2 | -2480.0 |
| CDH1 | -2485.0 |
| VPS11 | -2489.0 |
| RAC1 | -2500.0 |
| CUL3 | -2503.0 |
| SUMO1 | -2534.0 |
| FNTB | -2547.0 |
| AKT1 | -2548.0 |
| PSMD9 | -2570.0 |
| RPS5 | -2579.0 |
| PRKAR2A | -2605.0 |
| RPS6 | -2673.0 |
| PATJ | -2724.0 |
| DOCK2 | -2783.0 |
| AAAS | -2839.0 |
| SUGT1 | -2843.0 |
| ATP1B3 | -2856.0 |
| EEF1A1 | -2905.0 |
| STAM | -2995.0 |
| GTF2E2 | -3037.0 |
| PARP4 | -3072.0 |
| RPL39L | -3132.0 |
| GPC1 | -3133.0 |
| NCBP2 | -3139.0 |
| FXYD3 | -3156.0 |
| PARP14 | -3159.0 |
| PRKAR2B | -3186.0 |
| CSNK1A1 | -3215.0 |
| ANO2 | -3233.0 |
| POLR2B | -3234.0 |
| ELOA2 | -3237.0 |
| RIGI | -3256.0 |
| SP1 | -3275.0 |
| CHMP2B | -3280.0 |
| RPL37 | -3282.0 |
| HLA-B | -3298.0 |
| FNTA | -3311.0 |
| TAF4 | -3407.0 |
| AP2A2 | -3410.0 |
| ELMO2 | -3411.0 |
| NUP153 | -3416.0 |
| GNGT1 | -3424.0 |
| RAE1 | -3503.0 |
| DYNLL1 | -3541.0 |
| ANO3 | -3578.0 |
| CDK9 | -3594.0 |
| IFNB1 | -3599.0 |
| PIK3R4 | -3618.0 |
| MYO10 | -3654.0 |
| RANBP1 | -3685.0 |
| PLK2 | -3722.0 |
| MET | -3729.0 |
| LTF | -3752.0 |
| UBA52 | -3755.0 |
| DPEP1 | -3814.0 |
| CPSF4 | -3838.0 |
| TJP1 | -3931.0 |
| TRIM27 | -3955.0 |
| RANGAP1 | -3961.0 |
| SEC24D | -3966.0 |
| NELFA | -3973.0 |
| POM121C | -4045.0 |
| FXYD1 | -4056.0 |
| SYT2 | -4070.0 |
| SUDS3 | -4129.0 |
| RPS15 | -4150.0 |
| SRC | -4161.0 |
| GJA1 | -4200.0 |
| MOGS | -4208.0 |
| PDPK1 | -4211.0 |
| SMAD3 | -4228.0 |
| GNG4 | -4250.0 |
| REST | -4269.0 |
| SH3GL2 | -4275.0 |
| SUPT5H | -4276.0 |
| CLTA | -4284.0 |
| SEC24A | -4319.0 |
| APOBEC3G | -4322.0 |
| MAN2A1 | -4335.0 |
| TUBA1C | -4357.0 |
| NCOR1 | -4394.0 |
| NCOR2 | -4436.0 |
| WASL | -4439.0 |
| MTA1 | -4459.0 |
| TUBA1B | -4469.0 |
| MTA3 | -4477.0 |
| TMPRSS2 | -4484.0 |
| PLCG2 | -4486.0 |
| GTF2F1 | -4505.0 |
| TAF3 | -4514.0 |
| ITPR1 | -4562.0 |
| GPC6 | -4579.0 |
| TSG101 | -4633.0 |
| RPL24 | -4644.0 |
| RPS9 | -4650.0 |
| PSMB5 | -4687.0 |
| POLR2F | -4762.0 |
| VAV2 | -4801.0 |
| GNAT3 | -4821.0 |
| TAF2 | -4881.0 |
| H2BC9 | -4907.5 |
| H3C7 | -4907.5 |
| CDK7 | -4917.0 |
| SEC24C | -4936.0 |
| H4C5 | -4941.0 |
| NELFB | -4963.0 |
| ABI2 | -4983.0 |
| AP1G1 | -4987.0 |
| VPS36 | -5045.0 |
| HMOX1 | -5069.0 |
| PARP6 | -5099.0 |
| RPL4 | -5128.0 |
| KEAP1 | -5174.0 |
| PRKCSH | -5186.0 |
| VPS4A | -5196.0 |
| PSMD7 | -5198.0 |
| GTF2B | -5239.0 |
| FCGR3A | -5243.0 |
| TUBA3D | -5264.0 |
| KPNA3 | -5285.0 |
| RPL27 | -5306.0 |
| EGFR | -5320.0 |
| PSMD4 | -5337.0 |
| SERPINE1 | -5361.0 |
| CTNND1 | -5414.0 |
| RPL18A | -5425.0 |
| POLR2C | -5430.0 |
| MAPK3 | -5444.0 |
| BRD4 | -5452.0 |
| NUP214 | -5472.0 |
| RNMT | -5497.0 |
| PRKAR1B | -5514.0 |
| COMT | -5556.0 |
| AKT3 | -5586.0 |
| CHD3 | -5589.0 |
| NEDD4L | -5629.0 |
| SEC13 | -5670.0 |
| BST2 | -5683.0 |
| JAK3 | -5722.0 |
| HLA-C | -5724.0 |
| RPL22 | -5765.0 |
| ADCY9 | -5772.0 |
| H2BC21 | -5773.0 |
| RPLP2 | -5777.0 |
| DVL2 | -5810.0 |
| TAB2 | -5833.0 |
| PSMB1 | -5858.0 |
| ST3GAL3 | -5909.0 |
| RPS27L | -5945.0 |
| ANO5 | -5993.0 |
| ANTXR2 | -6004.0 |
| GSK3B | -6007.0 |
| POLR2J | -6011.0 |
| IL1R1 | -6039.0 |
| PARP16 | -6088.0 |
| DYNC1H1 | -6092.0 |
| ANO1 | -6140.0 |
| CD247 | -6156.0 |
| PPIG | -6168.0 |
| NUP50 | -6183.0 |
| MTA2 | -6196.0 |
| TRAF6 | -6221.0 |
| VPS41 | -6242.0 |
| ADCY1 | -6251.0 |
| POLR2H | -6261.0 |
| ADCY7 | -6373.0 |
| SNF8 | -6375.0 |
| IL1B | -6400.0 |
| ARPC1A | -6449.0 |
| PIK3C3 | -6505.0 |
| HSPA1A | -6507.0 |
| H2AC25 | -6550.0 |
| PSIP1 | -6596.0 |
| NUP210 | -6637.0 |
| RIPK1 | -6646.0 |
| MGAT5 | -6660.0 |
| G3BP1 | -6680.0 |
| H2BC26 | -6695.0 |
| CBLL1 | -6710.0 |
| RIPK3 | -6774.0 |
| ADCY5 | -6947.0 |
| TRIM4 | -6985.0 |
| VCP | -7056.0 |
| NFE2L2 | -7067.0 |
| STX1B | -7074.0 |
| NUP160 | -7169.0 |
| SUPT4H1 | -7200.0 |
| ST6GALNAC3 | -7209.0 |
| GPC5 | -7260.0 |
| GNB3 | -7261.0 |
| NUP62 | -7266.0 |
| NFKB1 | -7273.0 |
| FUT8 | -7288.0 |
| MAP2K2 | -7303.0 |
| ANO4 | -7322.0 |
| MGAT4C | -7329.0 |
| RNF213 | -7363.0 |
| SDC1 | -7406.0 |
| ANO7 | -7442.0 |
| GNAS | -7444.0 |
| IL17RA | -7446.0 |
| ROCK2 | -7492.0 |
| TKFC | -7546.0 |
| FKBP4 | -7549.0 |
| GSDMD | -7575.0 |
| WASF3 | -7580.0 |
| VPS16 | -7605.0 |
| CRK | -7608.0 |
| SRPK1 | -7616.0 |
| SAR1B | -7618.0 |
| RPN2 | -7620.0 |
| TUBB4A | -7633.0 |
| SDC4 | -7669.0 |
| ITPR3 | -7685.0 |
| PSMD8 | -7723.0 |
| GNG12 | -7753.0 |
| PLCG1 | -7786.0 |
| SDC2 | -7848.0 |
| TYK2 | -7870.0 |
| RUNX1 | -7923.0 |
| NCKAP1 | -7930.0 |
| TUBA1A | -8056.0 |
| P2RX4 | -8069.0 |
| RELA | -8093.0 |
| H2AC21 | -8120.0 |
| CYFIP1 | -8125.0 |
| RPL36 | -8155.0 |
| CRBN | -8173.0 |
| FURIN | -8263.0 |
| POLR2G | -8279.0 |
| ABL1 | -8289.0 |
| FCGR2A | -8299.0 |
| GNAZ | -8320.0 |
| ITGB1 | -8326.0 |
| SYT1 | -8405.0 |
| VPS4B | -8429.0 |
| GTF2A2 | -8491.0 |
| NCKIPSD | -8499.0 |
| H2AC14 | -8606.0 |
| RPS11 | -8626.0 |
| MAPK8 | -8692.0 |
| H2BC14 | -8730.0 |
| CTSL | -8793.0 |
| HLA-A | -8825.0 |
| GGT1 | -8830.0 |
| HSPG2 | -8928.0 |
| VPS37D | -8951.0 |
| MYH2 | -8973.0 |
| FXYD6 | -9012.0 |
| MGAT4A | -9023.0 |
| TPR | -9043.0 |
| TUSC3 | -9137.0 |
| CASP1 | -9200.0 |
| HLA-F | -9277.0 |
| H4C9 | -9282.0 |
| SEC24B | -9288.0 |
| WIPF3 | -9290.0 |
| ST3GAL4 | -9323.0 |
| SFN | -9368.0 |
| DPEP3 | -9370.0 |
| IRF7 | -9417.0 |
| ADCY3 | -9478.0 |
| TUBB2A | -9511.0 |
| PSMD5 | -9524.0 |
| CD4 | -9562.0 |
| IFNA6 | -9855.0 |
| GGT5 | -9900.0 |
| ATP1A4 | -9967.0 |
| RPL10L | -10090.0 |
| TUBA3C | -10220.0 |
| H2AC18 | -10224.5 |
| H2AC19 | -10224.5 |
| GEMIN2 | -10316.0 |
| GNGT2 | -10419.0 |
| IFNA5 | -10479.0 |
| TUBA3E | -10574.0 |
| MBL2 | -10811.0 |
| IFNA21 | -10852.0 |
REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY
| 1486 | |
|---|---|
| set | REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY |
| setSize | 94 |
| pANOVA | 9.45e-07 |
| s.dist | 0.293 |
| p.adjustANOVA | 0.000111 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL14 | 10215.0 |
| RPL18 | 10082.0 |
| RPL10A | 10035.0 |
| RPL23A | 9830.0 |
| RPS13 | 9737.0 |
| ATF4 | 9477.0 |
| RPL38 | 9474.0 |
| RPS21 | 9255.0 |
| RPLP0 | 9213.0 |
| RPL29 | 9165.0 |
| RPS3A | 8946.0 |
| RPL28 | 8875.0 |
| RPL36AL | 8459.5 |
| RPL22L1 | 8449.0 |
| RPL31 | 8273.0 |
| RPS24 | 8170.0 |
| RPS23 | 8094.0 |
| RPL26 | 8016.0 |
| RPS20 | 7907.0 |
| RPS29 | 7621.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL14 | 10215.0 |
| RPL18 | 10082.0 |
| RPL10A | 10035.0 |
| RPL23A | 9830.0 |
| RPS13 | 9737.0 |
| ATF4 | 9477.0 |
| RPL38 | 9474.0 |
| RPS21 | 9255.0 |
| RPLP0 | 9213.0 |
| RPL29 | 9165.0 |
| RPS3A | 8946.0 |
| RPL28 | 8875.0 |
| RPL36AL | 8459.5 |
| RPL22L1 | 8449.0 |
| RPL31 | 8273.0 |
| RPS24 | 8170.0 |
| RPS23 | 8094.0 |
| RPL26 | 8016.0 |
| RPS20 | 7907.0 |
| RPS29 | 7621.0 |
| RPL34 | 7423.0 |
| RPS19 | 7419.0 |
| RPS3 | 7411.0 |
| RPL41 | 7335.0 |
| RPL6 | 7304.0 |
| RPS27A | 7120.0 |
| RPL23 | 6935.0 |
| DDIT3 | 6748.0 |
| FAU | 6424.0 |
| RPL11 | 6414.0 |
| RPL21 | 6341.0 |
| RPL13 | 6125.0 |
| RPS26 | 6058.0 |
| RPL7A | 5991.0 |
| TRIB3 | 5967.0 |
| RPS16 | 5896.0 |
| RPL8 | 5822.0 |
| GCN1 | 5802.0 |
| RPS7 | 5716.0 |
| RPL26L1 | 5531.0 |
| RPS8 | 5431.0 |
| RPL37A | 5292.0 |
| IMPACT | 5258.0 |
| RPL3L | 5206.0 |
| RPL13A | 5131.5 |
| RPS10 | 5058.0 |
| RPL19 | 4913.0 |
| RPS18 | 4856.0 |
| RPL9 | 4760.0 |
| RPS27 | 4711.0 |
| CEBPB | 4682.0 |
| RPS12 | 4501.0 |
| RPL35 | 4434.0 |
| RPL35A | 4218.0 |
| RPL17 | 4202.0 |
| ATF2 | 3606.0 |
| RPSA | 3281.0 |
| RPL3 | 3240.0 |
| RPL12 | 2822.0 |
| RPS28 | 2669.0 |
| EIF2S1 | 2623.0 |
| RPL27A | 2494.0 |
| RPL15 | 2382.0 |
| RPL32 | 2362.0 |
| RPS15A | 2095.0 |
| EIF2S2 | 2093.0 |
| RPS25 | 1988.0 |
| RPLP1 | 1762.0 |
| RPL7 | 1442.0 |
| ASNS | 351.0 |
| RPL5 | -139.0 |
| RPS2 | -1028.0 |
| EIF2AK4 | -1363.0 |
| RPS14 | -1691.0 |
| RPL30 | -2061.0 |
| ATF3 | -2158.0 |
| RPS5 | -2579.0 |
| RPS6 | -2673.0 |
| RPL39L | -3132.0 |
| RPL37 | -3282.0 |
| UBA52 | -3755.0 |
| RPS15 | -4150.0 |
| CEBPG | -4609.0 |
| RPL24 | -4644.0 |
| RPS9 | -4650.0 |
| RPL4 | -5128.0 |
| RPL27 | -5306.0 |
| RPL18A | -5425.0 |
| RPL22 | -5765.0 |
| RPLP2 | -5777.0 |
| RPS27L | -5945.0 |
| RPL36 | -8155.0 |
| RPS11 | -8626.0 |
| RPL10L | -10090.0 |
REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION
| 151 | |
|---|---|
| set | REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION |
| setSize | 87 |
| pANOVA | 1.36e-06 |
| s.dist | 0.3 |
| p.adjustANOVA | 0.000149 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL14 | 10215.0 |
| EEF1A2 | 10153.0 |
| RPL18 | 10082.0 |
| RPL10A | 10035.0 |
| RPL23A | 9830.0 |
| RPS13 | 9737.0 |
| RPL38 | 9474.0 |
| RPS21 | 9255.0 |
| RPLP0 | 9213.0 |
| RPL29 | 9165.0 |
| RPS3A | 8946.0 |
| RPL28 | 8875.0 |
| RPL36AL | 8459.5 |
| RPL22L1 | 8449.0 |
| RPL31 | 8273.0 |
| RPS24 | 8170.0 |
| RPS23 | 8094.0 |
| RPL26 | 8016.0 |
| RPS20 | 7907.0 |
| RPS29 | 7621.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL14 | 10215.0 |
| EEF1A2 | 10153.0 |
| RPL18 | 10082.0 |
| RPL10A | 10035.0 |
| RPL23A | 9830.0 |
| RPS13 | 9737.0 |
| RPL38 | 9474.0 |
| RPS21 | 9255.0 |
| RPLP0 | 9213.0 |
| RPL29 | 9165.0 |
| RPS3A | 8946.0 |
| RPL28 | 8875.0 |
| RPL36AL | 8459.5 |
| RPL22L1 | 8449.0 |
| RPL31 | 8273.0 |
| RPS24 | 8170.0 |
| RPS23 | 8094.0 |
| RPL26 | 8016.0 |
| RPS20 | 7907.0 |
| RPS29 | 7621.0 |
| RPL34 | 7423.0 |
| RPS19 | 7419.0 |
| RPS3 | 7411.0 |
| RPL41 | 7335.0 |
| RPL6 | 7304.0 |
| RPS27A | 7120.0 |
| EEF1D | 7050.0 |
| RPL23 | 6935.0 |
| EEF1G | 6755.0 |
| FAU | 6424.0 |
| RPL11 | 6414.0 |
| RPL21 | 6341.0 |
| RPL13 | 6125.0 |
| RPS26 | 6058.0 |
| RPL7A | 5991.0 |
| RPS16 | 5896.0 |
| RPL8 | 5822.0 |
| RPS7 | 5716.0 |
| RPL26L1 | 5531.0 |
| RPS8 | 5431.0 |
| RPL37A | 5292.0 |
| RPL3L | 5206.0 |
| RPL13A | 5131.5 |
| RPS10 | 5058.0 |
| RPL19 | 4913.0 |
| RPS18 | 4856.0 |
| RPL9 | 4760.0 |
| RPS27 | 4711.0 |
| RPS12 | 4501.0 |
| RPL35 | 4434.0 |
| RPL35A | 4218.0 |
| RPL17 | 4202.0 |
| RPSA | 3281.0 |
| RPL3 | 3240.0 |
| RPL12 | 2822.0 |
| RPS28 | 2669.0 |
| RPL27A | 2494.0 |
| RPL15 | 2382.0 |
| RPL32 | 2362.0 |
| RPS15A | 2095.0 |
| RPS25 | 1988.0 |
| RPLP1 | 1762.0 |
| RPL7 | 1442.0 |
| EEF2 | 562.0 |
| EEF1B2 | 213.0 |
| RPL5 | -139.0 |
| RPS2 | -1028.0 |
| RPS14 | -1691.0 |
| RPL30 | -2061.0 |
| RPS5 | -2579.0 |
| RPS6 | -2673.0 |
| EEF1A1 | -2905.0 |
| RPL39L | -3132.0 |
| RPL37 | -3282.0 |
| UBA52 | -3755.0 |
| RPS15 | -4150.0 |
| RPL24 | -4644.0 |
| RPS9 | -4650.0 |
| RPL4 | -5128.0 |
| RPL27 | -5306.0 |
| RPL18A | -5425.0 |
| RPL22 | -5765.0 |
| RPLP2 | -5777.0 |
| RPS27L | -5945.0 |
| RPL36 | -8155.0 |
| RPS11 | -8626.0 |
| RPL10L | -10090.0 |
REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA
| 1146 | |
|---|---|
| set | REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA |
| setSize | 263 |
| pANOVA | 1.84e-06 |
| s.dist | 0.171 |
| p.adjustANOVA | 0.000188 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| THOC3 | 10946 |
| SRSF6 | 10598 |
| POLR2K | 10402 |
| LSM8 | 10352 |
| LENG1 | 10140 |
| THOC6 | 10125 |
| ACIN1 | 10116 |
| FUS | 10080 |
| SDE2 | 10050 |
| SNRNP25 | 10044 |
| SNRPB2 | 10026 |
| WBP11 | 9955 |
| CSTF2T | 9749 |
| RBM8A | 9578 |
| PRKRIP1 | 9540 |
| CCDC12 | 9515 |
| HNRNPR | 9325 |
| PCBP1 | 9188 |
| CWC22 | 9154 |
| HNRNPA1 | 8950 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| THOC3 | 10946 |
| SRSF6 | 10598 |
| POLR2K | 10402 |
| LSM8 | 10352 |
| LENG1 | 10140 |
| THOC6 | 10125 |
| ACIN1 | 10116 |
| FUS | 10080 |
| SDE2 | 10050 |
| SNRNP25 | 10044 |
| SNRPB2 | 10026 |
| WBP11 | 9955 |
| CSTF2T | 9749 |
| RBM8A | 9578 |
| PRKRIP1 | 9540 |
| CCDC12 | 9515 |
| HNRNPR | 9325 |
| PCBP1 | 9188 |
| CWC22 | 9154 |
| HNRNPA1 | 8950 |
| POM121 | 8943 |
| BUD13 | 8917 |
| SNU13 | 8897 |
| CPSF6 | 8868 |
| DHX35 | 8846 |
| PRCC | 8826 |
| DHX8 | 8808 |
| SAP18 | 8722 |
| HNRNPA3 | 8653 |
| METTL14 | 8628 |
| TRA2B | 8610 |
| SMNDC1 | 8551 |
| RBM7 | 8508 |
| SRSF1 | 8481 |
| DDX39B | 8477 |
| SF1 | 8324 |
| SNRNP35 | 8137 |
| ALYREF | 8040 |
| SF3A3 | 8036 |
| GPATCH1 | 7963 |
| ZC3H11A | 7947 |
| POLR2I | 7943 |
| WBP4 | 7909 |
| LSM3 | 7788 |
| NUP155 | 7761 |
| XAB2 | 7738 |
| SNW1 | 7713 |
| ZMAT2 | 7687 |
| CPSF2 | 7686 |
| EIF4E | 7566 |
| HSPA8 | 7490 |
| SF3A2 | 7446 |
| ZCRB1 | 7357 |
| PPIL4 | 7317 |
| LSM5 | 7137 |
| PPIH | 7024 |
| HNRNPU | 6963 |
| SEH1L | 6838 |
| NUP35 | 6822 |
| NUP85 | 6688 |
| SF3A1 | 6611 |
| LSM6 | 6601 |
| CDC40 | 6559 |
| SF3B4 | 6527 |
| HNRNPM | 6478 |
| U2AF1L4 | 6453 |
| EIF4A3 | 6420 |
| U2SURP | 6325 |
| PCF11 | 6318 |
| SNRNP27 | 6315 |
| NUP37 | 6306 |
| NXT1 | 6293 |
| RBM25 | 6214 |
| SNRNP48 | 6085 |
| DDX5 | 6081 |
| PDCD7 | 5973 |
| NUP43 | 5921 |
| PPWD1 | 5778 |
| CDC5L | 5770 |
| CSTF3 | 5738 |
| PRPF38A | 5727 |
| NCBP1 | 5705 |
| NUP54 | 5644 |
| UBL5 | 5627 |
| PABPN1 | 5490 |
| SNRNP70 | 5447 |
| CSTF1 | 5411 |
| SRSF3 | 5357 |
| LSM7 | 5224 |
| SNRPF | 5221 |
| SNRPD2 | 5177 |
| SF3B3 | 5113 |
| CWC15 | 5108 |
| SRSF7 | 5105 |
| RBM5 | 5075 |
| NUP107 | 5069 |
| IK | 4985 |
| POLDIP3 | 4943 |
| HNRNPC | 4936 |
| NUP88 | 4788 |
| NUP133 | 4676 |
| PRPF19 | 4618 |
| NSRP1 | 4543 |
| RNPS1 | 4528 |
| SF3B1 | 4515 |
| DHX16 | 4492 |
| LSM2 | 4491 |
| PCBP2 | 4487 |
| FAM32A | 4431 |
| SLU7 | 4319 |
| PPP1R8 | 4282 |
| SARNP | 4167 |
| CASC3 | 4044 |
| POLR2A | 3916 |
| SNRNP40 | 3887 |
| HNRNPA2B1 | 3853 |
| SRSF2 | 3788 |
| NUP205 | 3738 |
| SYMPK | 3608 |
| DDX39A | 3522 |
| SNRPG | 3425 |
| SF3B2 | 3227 |
| RBM42 | 3200 |
| POLR2E | 3177 |
| DHX15 | 3157 |
| SNRPA | 3000 |
| USP39 | 2963 |
| GTF2F2 | 2945 |
| CPSF7 | 2925 |
| NUP42 | 2844 |
| CHTOP | 2800 |
| ISY1 | 2794 |
| NUP93 | 2792 |
| NXF1 | 2722 |
| HNRNPD | 2711 |
| NUP58 | 2703 |
| RANBP2 | 2651 |
| BUD31 | 2642 |
| MFAP1 | 2472 |
| YBX1 | 2391 |
| SMU1 | 2278 |
| THOC7 | 2236 |
| LUC7L3 | 2199 |
| NUDT21 | 2107 |
| POLR2D | 2025 |
| RNPC3 | 2017 |
| MTREX | 1999 |
| CPSF1 | 1778 |
| SRSF4 | 1674 |
| SNRPD1 | 1669 |
| BCAS2 | 1531 |
| PRPF3 | 1521 |
| RBM17 | 1505 |
| SRRT | 1488 |
| SNRPD3 | 1285 |
| SF3B5 | 1282 |
| WDR70 | 1161 |
| SNRPE | 1082 |
| PRPF40A | 1016 |
| FYTTD1 | 934 |
| WDR33 | 931 |
| TFIP11 | 924 |
| DDX23 | 718 |
| PRPF31 | 669 |
| CWF19L2 | 612 |
| HNRNPK | 537 |
| DHX38 | 488 |
| CWC25 | 432 |
| RBM39 | 422 |
| SRSF9 | 313 |
| PRPF18 | 75 |
| GCFC2 | 71 |
| CACTIN | 69 |
| U2AF2 | -78 |
| PRPF4 | -97 |
| SRSF10 | -125 |
| SNRPA1 | -241 |
| PRPF8 | -262 |
| HNRNPL | -321 |
| NUP98 | -351 |
| DDX42 | -575 |
| SNRNP200 | -715 |
| AQR | -718 |
| PLRG1 | -765 |
| CLP1 | -801 |
| THOC1 | -929 |
| POLR2L | -971 |
| SRSF5 | -979 |
| PPIL3 | -1003 |
| DDX46 | -1107 |
| SNRPB | -1171 |
| NDC1 | -1433 |
| ZNF830 | -1443 |
| PTBP1 | -1545 |
| HNRNPF | -1749 |
| MAGOHB | -1800 |
| NUP188 | -1877 |
| HNRNPH1 | -2127 |
| CHERP | -2247 |
| THOC5 | -2259 |
| CPSF3 | -2788 |
| AAAS | -2839 |
| SRRM2 | -2879 |
| NCBP2 | -3139 |
| POLR2B | -3234 |
| PNN | -3265 |
| SYF2 | -3308 |
| PPIL2 | -3402 |
| NUP153 | -3416 |
| RAE1 | -3503 |
| PRPF6 | -3660 |
| PUF60 | -3784 |
| CPSF4 | -3838 |
| POM121C | -4045 |
| CCAR1 | -4182 |
| SRSF11 | -4246 |
| SNIP1 | -4467 |
| SART1 | -4493 |
| GTF2F1 | -4505 |
| PHF5A | -4716 |
| POLR2F | -4762 |
| YJU2 | -5034 |
| EFTUD2 | -5125 |
| POLR2C | -5430 |
| NUP214 | -5472 |
| PPIL1 | -5576 |
| TXNL4A | -5645 |
| SEC13 | -5670 |
| SRRM1 | -5879 |
| PAPOLA | -5925 |
| POLR2J | -6011 |
| CWC27 | -6061 |
| PPIG | -6168 |
| DDX41 | -6179 |
| NUP50 | -6183 |
| POLR2H | -6261 |
| METTL3 | -6395 |
| PPIE | -6522 |
| SRSF8 | -6558 |
| LSM4 | -6630 |
| NUP210 | -6637 |
| SNRPN | -6912 |
| DNAJC8 | -7033 |
| GLE1 | -7045 |
| C9orf78 | -7122 |
| NUP160 | -7169 |
| NUP62 | -7266 |
| SNRPC | -7354 |
| CRNKL1 | -7626 |
| CTNNBL1 | -7759 |
| SUGP1 | -7917 |
| ZMAT5 | -7941 |
| FIP1L1 | -8037 |
| WTAP | -8133 |
| TCERG1 | -8276 |
| POLR2G | -8279 |
| SRSF12 | -8418 |
| DHX9 | -8784 |
| RBM22 | -8902 |
| SF3B6 | -9034 |
| TPR | -9043 |
| SLBP | -9081 |
| MAGOH | -9309 |
REACTOME_KERATINIZATION
| 1073 | |
|---|---|
| set | REACTOME_KERATINIZATION |
| setSize | 210 |
| pANOVA | 4.5e-06 |
| s.dist | -0.184 |
| p.adjustANOVA | 0.000434 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| KRTAP27-1 | -10613 |
| KRTAP10-4 | -10526 |
| SPRR1B | -10519 |
| KRTAP20-2 | -10506 |
| KRT74 | -10488 |
| SPRR2G | -10487 |
| KRT39 | -10470 |
| LCE2B | -10453 |
| KRTAP11-1 | -10440 |
| KRTAP6-3 | -10401 |
| LIPJ | -10321 |
| KRTAP10-2 | -10310 |
| KRTAP3-2 | -10190 |
| LCE5A | -10173 |
| KRTAP13-2 | -10132 |
| KRTAP10-9 | -10103 |
| KRTAP10-7 | -10089 |
| KRT35 | -10044 |
| KRTAP13-1 | -10041 |
| KRTAP5-5 | -9995 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| KRTAP27-1 | -10613 |
| KRTAP10-4 | -10526 |
| SPRR1B | -10519 |
| KRTAP20-2 | -10506 |
| KRT74 | -10488 |
| SPRR2G | -10487 |
| KRT39 | -10470 |
| LCE2B | -10453 |
| KRTAP11-1 | -10440 |
| KRTAP6-3 | -10401 |
| LIPJ | -10321 |
| KRTAP10-2 | -10310 |
| KRTAP3-2 | -10190 |
| LCE5A | -10173 |
| KRTAP13-2 | -10132 |
| KRTAP10-9 | -10103 |
| KRTAP10-7 | -10089 |
| KRT35 | -10044 |
| KRTAP13-1 | -10041 |
| KRTAP5-5 | -9995 |
| KRT77 | -9944 |
| FLG | -9873 |
| KRT78 | -9854 |
| KRT6A | -9852 |
| KRTAP22-1 | -9844 |
| DSC2 | -9840 |
| KRTAP3-1 | -9778 |
| KRT17 | -9751 |
| KRT16 | -9747 |
| LIPK | -9713 |
| KRTAP19-3 | -9563 |
| KRTAP19-6 | -9443 |
| KRT33B | -9332 |
| KRT15 | -9145 |
| KRTAP21-3 | -9120 |
| KRTAP12-3 | -9101 |
| RPTN | -9099 |
| KRT86 | -9053 |
| KRTAP4-1 | -8947 |
| KRT79 | -8946 |
| SPINK5 | -8934 |
| JUP | -8895 |
| TGM1 | -8871 |
| KRTAP16-1 | -8854 |
| KRTAP12-2 | -8795 |
| KRTAP4-5 | -8693 |
| KRTAP2-4 | -8691 |
| KRT76 | -8415 |
| LCE3E | -8327 |
| FURIN | -8263 |
| DSC3 | -8239 |
| KRT40 | -8214 |
| KRTAP13-4 | -8044 |
| KRT23 | -7989 |
| KRTAP19-7 | -7983 |
| KRT33A | -7949 |
| KRT80 | -7834 |
| KAZN | -7793 |
| KRTAP19-1 | -7777 |
| SPRR3 | -7737 |
| KRTAP12-4 | -7702 |
| SPRR1A | -7639 |
| KLK5 | -7558 |
| KRTAP6-1 | -7534 |
| KRT82 | -7532 |
| LCE1F | -7531 |
| KLK12 | -7525 |
| LCE1E | -7473 |
| KRT81 | -7335 |
| KRT71 | -7230 |
| LCE6A | -7226 |
| KRTAP10-3 | -7198 |
| KRTAP2-1 | -7011 |
| LIPM | -6977 |
| KRT83 | -6862 |
| KRTAP13-3 | -6861 |
| PRSS8 | -6817 |
| KRTAP5-3 | -6609 |
| PKP3 | -6551 |
| PKP2 | -6492 |
| KRT37 | -6465 |
| PKP4 | -6335 |
| KRTAP17-1 | -6215 |
| LCE1C | -6142 |
| KRT2 | -5926 |
| KRTAP24-1 | -5832 |
| KRTAP5-6 | -5713 |
| DSG1 | -5553 |
| EVPL | -5510 |
| KRT34 | -5259 |
| CSTA | -5194 |
| KRT5 | -5141 |
| KRT19 | -5105 |
| KRT84 | -4820 |
| KRTAP1-1 | -4700 |
| KRT38 | -4663 |
| KRTAP12-1 | -4551 |
| KRT6B | -4497 |
| KRT7 | -4448 |
| KRTAP2-2 | -4399 |
| PPL | -4353 |
| LCE3D | -4344 |
| KRTAP10-5 | -4229 |
| PKP1 | -4060 |
| KRT10 | -3899 |
| LCE1B | -3580 |
| KRTAP1-3 | -3569 |
| KRTAP4-8 | -3565 |
| DSG3 | -3430 |
| KRTAP5-10 | -3198 |
| KRTAP19-8 | -3108 |
| SPINK6 | -3095 |
| KLK8 | -3085 |
| CAPNS1 | -3016 |
| PCSK6 | -2712 |
| KRTAP9-2 | -2487 |
| KRTAP4-3 | -2414 |
| KRTAP9-9 | -2342 |
| KRTAP1-5 | -2336 |
| KRT75 | -2326 |
| KRT1 | -2294 |
| KRT28 | -2109 |
| KRTAP5-9 | -1862 |
| TGM5 | -1540 |
| SPINK9 | -1467 |
| LCE2A | -1431 |
| KRTAP5-8 | -1392 |
| KRTAP26-1 | -1283 |
| KRT12 | -1192 |
| KRT18 | -1134 |
| KRTAP10-11 | -912 |
| KRT31 | -670 |
| KRT24 | -436 |
| KRTAP19-5 | -412 |
| KRT85 | -171 |
| DSC1 | 798 |
| KRT14 | 879 |
| KRTAP9-4 | 886 |
| KRT6C | 935 |
| LCE3B | 1042 |
| KRTAP10-8 | 1092 |
| KRT73 | 1249 |
| KRTAP4-7 | 1677 |
| KRT8 | 2185 |
| CASP14 | 2223 |
| KRTAP10-1 | 2568 |
| KRTAP9-3 | 2951 |
| KRTAP23-1 | 3321 |
| CAPN1 | 3476 |
| ST14 | 3539 |
| DSP | 3665 |
| CELA2A | 4115 |
| KRT13 | 4121 |
| KRTAP29-1 | 4273 |
| CDSN | 4457 |
| KLK14 | 4459 |
| LCE4A | 4531 |
| SPRR2F | 4582 |
| SPRR2A | 4601 |
| DSG4 | 4743 |
| KRT27 | 4777 |
| KRT4 | 5006 |
| LCE2D | 5612 |
| KRT3 | 5654 |
| KRTAP6-2 | 5983 |
| KRTAP1-4 | 6207 |
| KRTAP9-6 | 6250 |
| KRT26 | 6394 |
| KRTAP10-12 | 6411 |
| KRT36 | 6496 |
| KRTAP19-2 | 6616 |
| KRTAP10-6 | 6999 |
| KLK13 | 7082 |
| KRT25 | 7176 |
| KRTAP5-4 | 7179 |
| IVL | 7250 |
| KRTAP20-1 | 7583 |
| KRT32 | 7872 |
| LCE1A | 8003 |
| KRTAP10-10 | 8114 |
| KRTAP21-2 | 8179 |
| KRTAP2-3 | 8491 |
| SPRR2D | 8726 |
| DSG2 | 8780 |
| KRTAP4-4 | 8848 |
| KRTAP15-1 | 9093 |
| KRTAP25-1 | 9506 |
| KRTAP4-6 | 9520 |
| PERP | 9660 |
| KRTAP4-2 | 9869 |
| LELP1 | 9994 |
| KRT20 | 10084 |
| KRTAP21-1 | 10122 |
| KRTAP5-1 | 10133 |
| TCHH | 10142 |
| LCE2C | 10180 |
| KRTAP8-1 | 10394 |
| LCE3A | 10442 |
| KRTAP5-11 | 10499 |
| KRTAP3-3 | 10510 |
| KRT9 | 10562 |
| KRT72 | 10578 |
| KRTAP9-1 | 10624 |
| LIPN | 10639 |
| KRTAP5-2 | 10834 |
| KRTAP5-7 | 10849 |
| PI3 | 10905 |
| KRTAP4-11 | 10954 |
| KRTAP19-4 | 10956 |
| SPRR2E | 11070 |
REACTOME_UNFOLDED_PROTEIN_RESPONSE_UPR
| 623 | |
|---|---|
| set | REACTOME_UNFOLDED_PROTEIN_RESPONSE_UPR |
| setSize | 88 |
| pANOVA | 5.96e-06 |
| s.dist | 0.279 |
| p.adjustANOVA | 0.000544 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| DDX11 | 10995 |
| XBP1 | 10155 |
| KLHDC3 | 10121 |
| CREB3L3 | 10092 |
| WIPI1 | 9913 |
| ERN1 | 9896 |
| EXOSC5 | 9863 |
| EIF2AK3 | 9850 |
| SYVN1 | 9799 |
| CXCL8 | 9558 |
| PREB | 9523 |
| ATF4 | 9477 |
| EXOSC1 | 9393 |
| PPP2R5B | 9055 |
| KHSRP | 8781 |
| SHC1 | 8640 |
| HSPA5 | 8033 |
| EXOSC9 | 7985 |
| TPP1 | 7512 |
| DIS3 | 7503 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| DDX11 | 10995 |
| XBP1 | 10155 |
| KLHDC3 | 10121 |
| CREB3L3 | 10092 |
| WIPI1 | 9913 |
| ERN1 | 9896 |
| EXOSC5 | 9863 |
| EIF2AK3 | 9850 |
| SYVN1 | 9799 |
| CXCL8 | 9558 |
| PREB | 9523 |
| ATF4 | 9477 |
| EXOSC1 | 9393 |
| PPP2R5B | 9055 |
| KHSRP | 8781 |
| SHC1 | 8640 |
| HSPA5 | 8033 |
| EXOSC9 | 7985 |
| TPP1 | 7512 |
| DIS3 | 7503 |
| CREB3L1 | 7451 |
| LMNA | 7398 |
| YIF1A | 7327 |
| DNAJB11 | 7272 |
| TLN1 | 7118 |
| HDGF | 7091 |
| EDEM1 | 6990 |
| CALR | 6943 |
| EXOSC4 | 6868 |
| DDIT3 | 6748 |
| CREB3 | 6310 |
| ACADVL | 6282 |
| MBTPS1 | 6010 |
| CTDSP2 | 5869 |
| HYOU1 | 5825 |
| CREB3L4 | 5801 |
| NFYC | 5655 |
| GOSR2 | 5176 |
| SRPRB | 4813 |
| CEBPB | 4682 |
| GSK3A | 4632 |
| CUL7 | 4474 |
| EXOSC3 | 4242 |
| TATDN2 | 3828 |
| HERPUD1 | 3822 |
| CREBRF | 3663 |
| ADD1 | 3568 |
| ZBTB17 | 3370 |
| EXOSC7 | 3025 |
| EXTL2 | 3013 |
| PARN | 2863 |
| DNAJB9 | 2721 |
| EIF2S1 | 2623 |
| EIF2S2 | 2093 |
| DNAJC3 | 2083 |
| CXXC1 | 1985 |
| FKBP14 | 1925 |
| IGFBP1 | 1703 |
| SERP1 | 898 |
| WFS1 | 772 |
| KDELR3 | 582 |
| PDIA6 | 395 |
| NFYA | 361 |
| HSP90B1 | 354 |
| ASNS | 351 |
| EXTL1 | -113 |
| EXOSC8 | -119 |
| EXTL3 | -742 |
| CREB3L2 | -1197 |
| PLA2G4B | -1322 |
| EXOSC6 | -1460 |
| ATF3 | -2158 |
| SEC31A | -2590 |
| CCL2 | -2609 |
| ATP6V0D1 | -2636 |
| DCSTAMP | -3165 |
| GFPT1 | -3191 |
| DCP2 | -3374 |
| CEBPG | -4609 |
| SSR1 | -4735 |
| DCTN1 | -5418 |
| NFYB | -6538 |
| EXOSC2 | -6711 |
| SRPRA | -7160 |
| ATF6 | -7190 |
| MYDGF | -7315 |
| PDIA5 | -7319 |
| ARFGAP1 | -9536 |
REACTOME_MRNA_SPLICING
| 1143 | |
|---|---|
| set | REACTOME_MRNA_SPLICING |
| setSize | 197 |
| pANOVA | 6.41e-06 |
| s.dist | 0.186 |
| p.adjustANOVA | 0.000554 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| SRSF6 | 10598 |
| POLR2K | 10402 |
| LSM8 | 10352 |
| LENG1 | 10140 |
| ACIN1 | 10116 |
| FUS | 10080 |
| SDE2 | 10050 |
| SNRNP25 | 10044 |
| SNRPB2 | 10026 |
| WBP11 | 9955 |
| RBM8A | 9578 |
| PRKRIP1 | 9540 |
| CCDC12 | 9515 |
| HNRNPR | 9325 |
| PCBP1 | 9188 |
| CWC22 | 9154 |
| HNRNPA1 | 8950 |
| BUD13 | 8917 |
| SNU13 | 8897 |
| DHX35 | 8846 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SRSF6 | 10598 |
| POLR2K | 10402 |
| LSM8 | 10352 |
| LENG1 | 10140 |
| ACIN1 | 10116 |
| FUS | 10080 |
| SDE2 | 10050 |
| SNRNP25 | 10044 |
| SNRPB2 | 10026 |
| WBP11 | 9955 |
| RBM8A | 9578 |
| PRKRIP1 | 9540 |
| CCDC12 | 9515 |
| HNRNPR | 9325 |
| PCBP1 | 9188 |
| CWC22 | 9154 |
| HNRNPA1 | 8950 |
| BUD13 | 8917 |
| SNU13 | 8897 |
| DHX35 | 8846 |
| PRCC | 8826 |
| DHX8 | 8808 |
| SAP18 | 8722 |
| HNRNPA3 | 8653 |
| TRA2B | 8610 |
| SMNDC1 | 8551 |
| RBM7 | 8508 |
| SRSF1 | 8481 |
| DDX39B | 8477 |
| SF1 | 8324 |
| SNRNP35 | 8137 |
| ALYREF | 8040 |
| SF3A3 | 8036 |
| GPATCH1 | 7963 |
| POLR2I | 7943 |
| WBP4 | 7909 |
| LSM3 | 7788 |
| XAB2 | 7738 |
| SNW1 | 7713 |
| ZMAT2 | 7687 |
| HSPA8 | 7490 |
| SF3A2 | 7446 |
| ZCRB1 | 7357 |
| PPIL4 | 7317 |
| LSM5 | 7137 |
| PPIH | 7024 |
| HNRNPU | 6963 |
| SF3A1 | 6611 |
| LSM6 | 6601 |
| CDC40 | 6559 |
| SF3B4 | 6527 |
| HNRNPM | 6478 |
| U2AF1L4 | 6453 |
| EIF4A3 | 6420 |
| U2SURP | 6325 |
| SNRNP27 | 6315 |
| RBM25 | 6214 |
| SNRNP48 | 6085 |
| DDX5 | 6081 |
| PDCD7 | 5973 |
| PPWD1 | 5778 |
| CDC5L | 5770 |
| PRPF38A | 5727 |
| NCBP1 | 5705 |
| UBL5 | 5627 |
| SNRNP70 | 5447 |
| SRSF3 | 5357 |
| LSM7 | 5224 |
| SNRPF | 5221 |
| SNRPD2 | 5177 |
| SF3B3 | 5113 |
| CWC15 | 5108 |
| SRSF7 | 5105 |
| RBM5 | 5075 |
| IK | 4985 |
| HNRNPC | 4936 |
| PRPF19 | 4618 |
| NSRP1 | 4543 |
| RNPS1 | 4528 |
| SF3B1 | 4515 |
| DHX16 | 4492 |
| LSM2 | 4491 |
| PCBP2 | 4487 |
| FAM32A | 4431 |
| SLU7 | 4319 |
| PPP1R8 | 4282 |
| CASC3 | 4044 |
| POLR2A | 3916 |
| SNRNP40 | 3887 |
| HNRNPA2B1 | 3853 |
| SRSF2 | 3788 |
| SNRPG | 3425 |
| SF3B2 | 3227 |
| RBM42 | 3200 |
| POLR2E | 3177 |
| DHX15 | 3157 |
| SNRPA | 3000 |
| USP39 | 2963 |
| GTF2F2 | 2945 |
| ISY1 | 2794 |
| HNRNPD | 2711 |
| BUD31 | 2642 |
| MFAP1 | 2472 |
| YBX1 | 2391 |
| SMU1 | 2278 |
| LUC7L3 | 2199 |
| POLR2D | 2025 |
| RNPC3 | 2017 |
| MTREX | 1999 |
| SRSF4 | 1674 |
| SNRPD1 | 1669 |
| BCAS2 | 1531 |
| PRPF3 | 1521 |
| RBM17 | 1505 |
| SRRT | 1488 |
| SNRPD3 | 1285 |
| SF3B5 | 1282 |
| WDR70 | 1161 |
| SNRPE | 1082 |
| PRPF40A | 1016 |
| TFIP11 | 924 |
| DDX23 | 718 |
| PRPF31 | 669 |
| CWF19L2 | 612 |
| HNRNPK | 537 |
| DHX38 | 488 |
| CWC25 | 432 |
| RBM39 | 422 |
| SRSF9 | 313 |
| PRPF18 | 75 |
| GCFC2 | 71 |
| CACTIN | 69 |
| U2AF2 | -78 |
| PRPF4 | -97 |
| SRSF10 | -125 |
| SNRPA1 | -241 |
| PRPF8 | -262 |
| HNRNPL | -321 |
| DDX42 | -575 |
| SNRNP200 | -715 |
| AQR | -718 |
| PLRG1 | -765 |
| POLR2L | -971 |
| SRSF5 | -979 |
| PPIL3 | -1003 |
| DDX46 | -1107 |
| SNRPB | -1171 |
| ZNF830 | -1443 |
| PTBP1 | -1545 |
| HNRNPF | -1749 |
| MAGOHB | -1800 |
| HNRNPH1 | -2127 |
| CHERP | -2247 |
| SRRM2 | -2879 |
| NCBP2 | -3139 |
| POLR2B | -3234 |
| PNN | -3265 |
| SYF2 | -3308 |
| PPIL2 | -3402 |
| PRPF6 | -3660 |
| PUF60 | -3784 |
| CCAR1 | -4182 |
| SRSF11 | -4246 |
| SNIP1 | -4467 |
| SART1 | -4493 |
| GTF2F1 | -4505 |
| PHF5A | -4716 |
| POLR2F | -4762 |
| YJU2 | -5034 |
| EFTUD2 | -5125 |
| POLR2C | -5430 |
| PPIL1 | -5576 |
| TXNL4A | -5645 |
| SRRM1 | -5879 |
| POLR2J | -6011 |
| CWC27 | -6061 |
| PPIG | -6168 |
| DDX41 | -6179 |
| POLR2H | -6261 |
| PPIE | -6522 |
| SRSF8 | -6558 |
| LSM4 | -6630 |
| SNRPN | -6912 |
| DNAJC8 | -7033 |
| C9orf78 | -7122 |
| SNRPC | -7354 |
| CRNKL1 | -7626 |
| CTNNBL1 | -7759 |
| SUGP1 | -7917 |
| ZMAT5 | -7941 |
| TCERG1 | -8276 |
| POLR2G | -8279 |
| SRSF12 | -8418 |
| DHX9 | -8784 |
| RBM22 | -8902 |
| SF3B6 | -9034 |
| MAGOH | -9309 |
REACTOME_OLFACTORY_SIGNALING_PATHWAY
| 628 | |
|---|---|
| set | REACTOME_OLFACTORY_SIGNALING_PATHWAY |
| setSize | 348 |
| pANOVA | 7.18e-06 |
| s.dist | -0.14 |
| p.adjustANOVA | 0.000566 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| OR6C6 | -10854 |
| OR52R1 | -10810 |
| OR51F1 | -10793 |
| OR5H1 | -10775 |
| OR2A5 | -10736 |
| OR5AP2 | -10728 |
| OR51E1 | -10686 |
| OR5J2 | -10685 |
| OR51T1 | -10658 |
| OR8D2 | -10621 |
| OR8I2 | -10590 |
| OR2G6 | -10560 |
| OR2M3 | -10544 |
| OR52N1 | -10535 |
| OR5T3 | -10534 |
| OR13J1 | -10527 |
| OR2B6 | -10525 |
| OR1C1 | -10524 |
| OR2G3 | -10474 |
| OR4E2 | -10415 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| OR6C6 | -10854.0 |
| OR52R1 | -10810.0 |
| OR51F1 | -10793.0 |
| OR5H1 | -10775.0 |
| OR2A5 | -10736.0 |
| OR5AP2 | -10728.0 |
| OR51E1 | -10686.0 |
| OR5J2 | -10685.0 |
| OR51T1 | -10658.0 |
| OR8D2 | -10621.0 |
| OR8I2 | -10590.0 |
| OR2G6 | -10560.0 |
| OR2M3 | -10544.0 |
| OR52N1 | -10535.0 |
| OR5T3 | -10534.0 |
| OR13J1 | -10527.0 |
| OR2B6 | -10525.0 |
| OR1C1 | -10524.0 |
| OR2G3 | -10474.0 |
| OR4E2 | -10415.0 |
| OR5AN1 | -10409.0 |
| OR2M4 | -10400.0 |
| OR5M8 | -10396.0 |
| OR13G1 | -10296.0 |
| OR2A2 | -10294.0 |
| OR51M1 | -10293.0 |
| OR2L3 | -10291.0 |
| OR5K2 | -10242.0 |
| OR5K4 | -10208.0 |
| OR1N1 | -10192.0 |
| OR52D1 | -10186.0 |
| OR5T2 | -10185.0 |
| OR1Q1 | -10165.0 |
| OR6C76 | -10102.0 |
| OR2L8 | -10078.0 |
| OR8B4 | -9970.0 |
| OR5B2 | -9955.0 |
| OR10A6 | -9893.0 |
| OR5I1 | -9886.0 |
| OR6K2 | -9882.0 |
| OR6Y1 | -9867.0 |
| OR5M11 | -9819.0 |
| RTP1 | -9782.0 |
| OR2A12 | -9772.0 |
| OR6P1 | -9724.0 |
| OR5B21 | -9694.0 |
| OR10J5 | -9671.0 |
| OR51D1 | -9654.0 |
| OR51I2 | -9558.0 |
| OR51L1 | -9553.0 |
| OR12D2 | -9526.0 |
| OR5AR1 | -9519.0 |
| OR5B12 | -9516.0 |
| ADCY3 | -9478.0 |
| OR5L1 | -9458.0 |
| OR10J3 | -9366.0 |
| OR2C3 | -9336.0 |
| OR11A1 | -9335.0 |
| OR5P3 | -9296.0 |
| CNGA4 | -9273.0 |
| OR4M1 | -9255.0 |
| OR10K2 | -9179.0 |
| OR7D2 | -9104.0 |
| OR52E6 | -9090.0 |
| OR8H3 | -9077.0 |
| OR4D10 | -9071.0 |
| OR6S1 | -9051.0 |
| OR10K1 | -9049.0 |
| OR52J3 | -9030.0 |
| OR6F1 | -9022.0 |
| OR2AK2 | -9009.0 |
| OR6C2 | -8988.0 |
| OR10A5 | -8979.0 |
| OR51S1 | -8964.0 |
| OR7A5 | -8870.0 |
| OR1L3 | -8823.0 |
| OR13D1 | -8765.0 |
| OR10H4 | -8756.0 |
| OR6V1 | -8740.0 |
| OR2T27 | -8736.0 |
| OR52H1 | -8723.0 |
| OR5C1 | -8714.0 |
| OR4D11 | -8690.0 |
| OR2T6 | -8486.0 |
| OR2AT4 | -8475.0 |
| OR10A3 | -8419.0 |
| OR2M2 | -8400.0 |
| OR5A2 | -8347.0 |
| OR4C15 | -8323.0 |
| OR5L2 | -8315.0 |
| OR51A7 | -8310.0 |
| OR7G1 | -8248.0 |
| OR14C36 | -8185.0 |
| OR56A1 | -8128.0 |
| OR8K5 | -8103.0 |
| OR5P2 | -8029.0 |
| OR5D14 | -8023.0 |
| OR5V1 | -7877.0 |
| OR52E2 | -7855.0 |
| OR10H1 | -7826.0 |
| OR8U8 | -7784.0 |
| OR2Y1 | -7677.0 |
| OR8D1 | -7654.0 |
| OR8J3 | -7649.0 |
| OR8B12 | -7632.0 |
| OR2L13 | -7590.0 |
| OR10G7 | -7584.0 |
| OR10G2 | -7377.0 |
| OR4D6 | -7339.0 |
| OR52M1 | -7318.0 |
| OR51B6 | -7304.0 |
| OR10G8 | -7289.0 |
| OR8U1 | -7220.0 |
| OR5AS1 | -7182.0 |
| OR56B1 | -7154.0 |
| OR5M9 | -7107.0 |
| OR56A4 | -7070.0 |
| OR10A2 | -6878.0 |
| OR52E8 | -6873.0 |
| OR13C9 | -6797.0 |
| OR5F1 | -6781.0 |
| OR2L2 | -6740.0 |
| OR2F1 | -6728.0 |
| CNGB1 | -6692.0 |
| OR1L1 | -6665.0 |
| OR6C3 | -6602.0 |
| OR1S1 | -6531.0 |
| OR5B3 | -6448.0 |
| OR5H2 | -6376.0 |
| OR51F2 | -6371.0 |
| OR2T12 | -6318.0 |
| OR51B5 | -6274.0 |
| OR13F1 | -6220.0 |
| OR6C75 | -6121.0 |
| OR9Q2 | -6049.0 |
| OR9Q1 | -5971.0 |
| OR14A16 | -5941.0 |
| EBF1 | -5762.0 |
| OR1B1 | -5679.0 |
| OR9G1 | -5649.5 |
| OR9G9 | -5649.5 |
| OR56B4 | -5538.0 |
| OR2T1 | -5516.0 |
| OR52N2 | -5493.0 |
| OR8B8 | -5480.0 |
| OR10H3 | -5269.0 |
| OR6N1 | -5094.0 |
| OR10AD1 | -4999.0 |
| OR6T1 | -4960.0 |
| OR1D2 | -4955.0 |
| OR6Q1 | -4896.0 |
| OR52B6 | -4786.0 |
| OR7G2 | -4577.0 |
| OR4D1 | -4542.0 |
| OR51I1 | -4522.0 |
| OR8J1 | -4496.0 |
| OR2T3 | -4438.0 |
| OR4D5 | -4321.0 |
| OR11G2 | -4184.0 |
| OR8A1 | -4138.0 |
| OR2V2 | -3818.0 |
| OR2W3 | -3806.0 |
| OR1J2 | -3761.0 |
| OR5D16 | -3758.0 |
| OR6A2 | -3595.0 |
| OR8G5 | -3550.0 |
| OR10S1 | -3488.0 |
| OR4D2 | -3351.0 |
| ANO2 | -3233.0 |
| OR5AC2 | -3196.0 |
| OR2L5 | -3193.0 |
| OR10Z1 | -3155.0 |
| OR2A14 | -3113.0 |
| OR52A5 | -2976.0 |
| OR10C1 | -2952.0 |
| OR5K3 | -2947.0 |
| OR2B3 | -2921.0 |
| OR4N2 | -2889.0 |
| OR8D4 | -2668.0 |
| OR5AK2 | -2638.0 |
| OR10X1 | -2583.0 |
| OR5M3 | -2438.0 |
| OR4K1 | -2419.0 |
| OR8G1 | -2384.0 |
| OR52I2 | -2243.0 |
| OR7C1 | -2150.0 |
| OR10A4 | -1936.0 |
| OR56A5 | -1856.0 |
| OR8U3 | -1737.0 |
| OR11L1 | -1681.0 |
| OR5A1 | -1668.0 |
| OR6C1 | -1650.0 |
| OR5M1 | -1527.0 |
| OR4A16 | -1515.0 |
| OR4K14 | -1436.0 |
| OR6B3 | -1262.0 |
| OR6M1 | -1239.0 |
| OR52A1 | -1194.0 |
| RTP2 | -1143.0 |
| OR2C1 | -1126.0 |
| OR52W1 | -410.0 |
| OR8K1 | -396.0 |
| OR2H1 | -335.0 |
| OR2V1 | -287.0 |
| OR56A3 | -180.0 |
| OR2K2 | -176.0 |
| OR2Z1 | -65.0 |
| OR8B2 | 192.0 |
| OR7A17 | 298.0 |
| OR1F1 | 353.0 |
| OR1N2 | 355.0 |
| OR10G3 | 378.0 |
| OR6N2 | 453.0 |
| OR8K3 | 618.0 |
| OR3A3 | 709.0 |
| OR14J1 | 846.0 |
| OR6K3 | 926.0 |
| OR8H1 | 960.0 |
| OR51B2 | 1031.0 |
| OR10H2 | 1198.0 |
| OR12D3 | 1348.0 |
| OR9A4 | 1516.0 |
| OR10G4 | 1583.0 |
| OR13C8 | 1741.0 |
| OR51V1 | 1756.0 |
| OR2D3 | 1827.0 |
| OR52B2 | 1915.0 |
| OR1A2 | 2044.0 |
| OR51A2 | 2136.0 |
| OR10Q1 | 2166.0 |
| OR6X1 | 2590.0 |
| OR6C70 | 2634.0 |
| OR2W1 | 2754.0 |
| OR10W1 | 2812.0 |
| OR51B4 | 2998.0 |
| OR6C68 | 3042.0 |
| OR7C2 | 3230.0 |
| OR5K1 | 3254.0 |
| OR10G9 | 3293.0 |
| OR2T33 | 3637.0 |
| OR10AG1 | 3681.0 |
| OR1E2 | 3752.0 |
| OR4K13 | 3771.0 |
| OR2B11 | 3813.0 |
| OR6K6 | 3833.0 |
| OR7A10 | 3856.0 |
| OR8S1 | 3869.0 |
| OR9G4 | 4147.0 |
| GNAL | 4308.0 |
| OR14I1 | 4334.0 |
| OR3A2 | 4394.0 |
| OR4C3 | 4566.0 |
| LHX2 | 4613.0 |
| OR4X2 | 4693.0 |
| OR11H4 | 4791.0 |
| OR10H5 | 4852.0 |
| OR2F2 | 4932.0 |
| OR10A7 | 5665.0 |
| OR2B2 | 5706.0 |
| OR1J4 | 5763.0 |
| OR4A5 | 5820.0 |
| OR4B1 | 6037.0 |
| OR4C45 | 6093.0 |
| OR9I1 | 6129.0 |
| OR2T4 | 6191.0 |
| OR1A1 | 6370.0 |
| OR4K17 | 6511.0 |
| OR2G2 | 6652.0 |
| OR1G1 | 6884.0 |
| OR10T2 | 6946.0 |
| OR2AG2 | 7021.0 |
| OR1L8 | 7066.0 |
| OR51G1 | 7233.0 |
| OR4S1 | 7263.0 |
| OR5H6 | 7316.0 |
| OR5T1 | 7464.0 |
| GNB1 | 7509.0 |
| OR4A15 | 7657.0 |
| OR4L1 | 7886.0 |
| OR6B1 | 8134.0 |
| OR2J2 | 8148.0 |
| OR2AP1 | 8289.0 |
| OR1I1 | 8352.0 |
| OR5W2 | 8354.0 |
| OR4C6 | 8379.0 |
| OR5D18 | 8385.0 |
| OR2D2 | 8494.0 |
| OR2M5 | 8523.0 |
| OR11H6 | 8600.0 |
| OR10J1 | 8773.0 |
| OR13C3 | 8825.0 |
| OR4C16 | 8867.0 |
| REEP1 | 8878.0 |
| LDB1 | 8879.0 |
| OR1K1 | 8899.0 |
| OR52E4 | 9057.0 |
| OR6B2 | 9080.0 |
| OR6C65 | 9179.0 |
| OR2T11 | 9244.0 |
| OR1L6 | 9273.0 |
| OR4K5 | 9299.0 |
| OR2AE1 | 9347.0 |
| OR9A2 | 9358.0 |
| OR1S2 | 9383.0 |
| OR51E2 | 9398.0 |
| OR5M10 | 9399.0 |
| OR6C74 | 9425.0 |
| OR13A1 | 9486.0 |
| OR2T8 | 9527.0 |
| OR52K1 | 9570.0 |
| OR13C2 | 9625.0 |
| OR2AG1 | 9733.0 |
| OR52L1 | 9742.0 |
| OR52K2 | 9750.0 |
| OR1M1 | 9752.0 |
| OR2H2 | 9770.0 |
| OR4F15 | 9800.0 |
| OR7G3 | 9819.0 |
| OR3A1 | 9879.0 |
| OR7E24 | 9975.0 |
| OR5B17 | 10000.0 |
| OR4K15 | 10185.0 |
| OR4F6 | 10203.0 |
| OR10V1 | 10219.0 |
| OR13C4 | 10245.0 |
| OR7D4 | 10288.0 |
| OR5D13 | 10360.0 |
| OR10P1 | 10404.0 |
| OR1J1 | 10445.0 |
| OR2S2 | 10467.0 |
| OR4N5 | 10475.0 |
| OR5AU1 | 10534.0 |
| OR51Q1 | 10548.0 |
| GNG13 | 10553.0 |
| OR1E1 | 10619.0 |
| OR4K2 | 10626.0 |
| OR4D9 | 10688.0 |
| OR51G2 | 10708.0 |
| OR9K2 | 10730.0 |
| OR4X1 | 10757.0 |
| OR1L4 | 10761.0 |
| OR6C4 | 10831.0 |
| OR4A47 | 10848.0 |
| OR52I1 | 10877.0 |
| OR5H15 | 10908.0 |
| OR2M7 | 10981.0 |
| OR4C46 | 11021.0 |
| OR4C12 | 11031.0 |
REACTOME_CELL_CYCLE
| 190 | |
|---|---|
| set | REACTOME_CELL_CYCLE |
| setSize | 666 |
| pANOVA | 7.24e-06 |
| s.dist | 0.102 |
| p.adjustANOVA | 0.000566 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TUBG2 | 10998 |
| PRDM9 | 10964 |
| E2F1 | 10764 |
| CDKN2D | 10762 |
| H4C8 | 10752 |
| LIN52 | 10563 |
| CDK4 | 10506 |
| POLE3 | 10464 |
| POLR2K | 10402 |
| CHMP4C | 10392 |
| POLD4 | 10382 |
| CENPQ | 10378 |
| PSMD12 | 10325 |
| CDKN2B | 10314 |
| DYNC1LI2 | 10216 |
| BANF1 | 10027 |
| USO1 | 9986 |
| PSMC6 | 9977 |
| ESPL1 | 9956 |
| KNTC1 | 9932 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TUBG2 | 10998.0 |
| PRDM9 | 10964.0 |
| E2F1 | 10764.0 |
| CDKN2D | 10762.0 |
| H4C8 | 10752.0 |
| LIN52 | 10563.0 |
| CDK4 | 10506.0 |
| POLE3 | 10464.0 |
| POLR2K | 10402.0 |
| CHMP4C | 10392.0 |
| POLD4 | 10382.0 |
| CENPQ | 10378.0 |
| PSMD12 | 10325.0 |
| CDKN2B | 10314.0 |
| DYNC1LI2 | 10216.0 |
| BANF1 | 10027.0 |
| USO1 | 9986.0 |
| PSMC6 | 9977.0 |
| ESPL1 | 9956.0 |
| KNTC1 | 9932.0 |
| H2AJ | 9870.0 |
| PSMB3 | 9858.0 |
| PSMC3IP | 9842.0 |
| TUBG1 | 9820.0 |
| RUVBL2 | 9628.0 |
| UBC | 9476.0 |
| DSN1 | 9391.0 |
| MCM2 | 9367.0 |
| RBX1 | 9293.0 |
| BABAM1 | 9283.0 |
| RAD1 | 9237.0 |
| KAT5 | 9221.0 |
| MCM10 | 9189.0 |
| LIN37 | 9132.0 |
| TUBB6 | 9058.0 |
| PPP2R5B | 9055.0 |
| H3C10 | 9015.0 |
| FEN1 | 9002.0 |
| GINS2 | 8991.0 |
| H3C11 | 8963.0 |
| POM121 | 8943.0 |
| ZWINT | 8928.0 |
| LEMD3 | 8915.0 |
| H4C12 | 8883.0 |
| BUB1B | 8870.0 |
| SSNA1 | 8831.0 |
| AURKB | 8795.0 |
| CSNK2B | 8721.0 |
| PPP2R5D | 8711.0 |
| ITGB3BP | 8707.0 |
| H4C2 | 8690.0 |
| PSME2 | 8685.0 |
| LYN | 8661.0 |
| H3-3A | 8639.0 |
| BARD1 | 8638.0 |
| H2BC13 | 8609.0 |
| MDM4 | 8496.0 |
| CDKN1B | 8453.0 |
| WRAP53 | 8437.0 |
| CCNH | 8435.0 |
| CKS1B | 8430.0 |
| H2BC1 | 8383.0 |
| CLIP1 | 8357.0 |
| TUBAL3 | 8355.0 |
| DYNLL2 | 8325.0 |
| DNA2 | 8298.0 |
| SIRT2 | 8280.0 |
| KIF23 | 8268.0 |
| PSMB4 | 8180.0 |
| TP53 | 8108.0 |
| NEK9 | 8080.0 |
| H3C12 | 8052.0 |
| CDC45 | 7992.0 |
| TUBB4B | 7956.0 |
| POLR2I | 7943.0 |
| PSMD13 | 7901.0 |
| RBBP8 | 7822.0 |
| H2AZ2 | 7814.0 |
| DSCC1 | 7785.0 |
| TUBB3 | 7767.0 |
| NUP155 | 7761.0 |
| H2AC7 | 7754.5 |
| H2BC7 | 7754.5 |
| PPP1CB | 7737.0 |
| CENPM | 7709.0 |
| PSME4 | 7705.0 |
| CENPL | 7683.0 |
| UBB | 7674.0 |
| PSMB2 | 7641.0 |
| NDC80 | 7594.0 |
| CDC25A | 7593.0 |
| POLD1 | 7462.0 |
| KMT5A | 7432.0 |
| AHCTF1 | 7417.0 |
| LMNA | 7398.0 |
| CCNB1 | 7396.0 |
| GAR1 | 7394.0 |
| ABRAXAS1 | 7372.0 |
| PSMB11 | 7359.0 |
| CDKN2A | 7282.0 |
| H4C16 | 7260.0 |
| RAD51C | 7257.0 |
| TUBA8 | 7215.0 |
| PSMA6 | 7190.0 |
| TPX2 | 7183.0 |
| BIRC5 | 7158.0 |
| RAB1B | 7123.0 |
| RPS27A | 7120.0 |
| MASTL | 7036.0 |
| CDC25C | 7020.0 |
| PSMA1 | 7018.0 |
| CCND3 | 6976.0 |
| ANAPC11 | 6955.0 |
| CDK2 | 6939.0 |
| CHEK1 | 6909.0 |
| SHQ1 | 6859.0 |
| NPM1 | 6858.0 |
| RBBP4 | 6844.0 |
| SEH1L | 6838.0 |
| NUP35 | 6822.0 |
| TUBB8 | 6817.0 |
| ORC1 | 6803.0 |
| BUB1 | 6792.0 |
| TUBB2B | 6768.0 |
| NCAPG | 6722.0 |
| MIS18BP1 | 6713.0 |
| RAD21 | 6706.0 |
| LBR | 6693.0 |
| NUP85 | 6688.0 |
| PSMD3 | 6672.0 |
| MDC1 | 6671.0 |
| RHNO1 | 6649.0 |
| RAD9A | 6635.0 |
| H2AC8 | 6630.0 |
| CENPC | 6615.0 |
| SYCE3 | 6554.0 |
| MCM5 | 6536.0 |
| VRK2 | 6403.0 |
| NUP37 | 6306.0 |
| CTC1 | 6152.0 |
| RNF8 | 6146.0 |
| NHP2 | 6142.0 |
| ZW10 | 6123.0 |
| H3-3B | 6110.0 |
| H2BC8 | 6087.0 |
| SKA2 | 6014.0 |
| AURKA | 5946.0 |
| H4C3 | 5935.0 |
| NUP43 | 5921.0 |
| YWHAB | 5879.0 |
| KNL1 | 5868.0 |
| ANAPC10 | 5865.0 |
| H4C1 | 5864.0 |
| CKAP5 | 5856.0 |
| MLH1 | 5844.0 |
| NEK2 | 5826.0 |
| DCTN2 | 5812.0 |
| B9D2 | 5784.0 |
| CENPT | 5768.0 |
| PDS5B | 5760.0 |
| RB1 | 5745.0 |
| PSMC1 | 5715.0 |
| MCM4 | 5708.0 |
| RAN | 5697.0 |
| CC2D1B | 5682.0 |
| SGO2 | 5675.0 |
| RPA1 | 5651.0 |
| NUP54 | 5644.0 |
| ESCO2 | 5634.0 |
| PSMD2 | 5624.0 |
| MRE11 | 5620.0 |
| H3C1 | 5598.0 |
| NCAPD2 | 5528.0 |
| FOXM1 | 5480.0 |
| RAB8A | 5455.0 |
| PAFAH1B1 | 5441.0 |
| DYRK1A | 5435.0 |
| PSMA5 | 5362.0 |
| CHTF8 | 5353.0 |
| PLK1 | 5347.0 |
| ANAPC2 | 5346.0 |
| KIF2C | 5265.0 |
| SMC3 | 5251.0 |
| DBF4 | 5250.0 |
| PSMA4 | 5246.0 |
| CEP70 | 5241.0 |
| CDC14A | 5239.0 |
| PIF1 | 5215.0 |
| PSMC5 | 5193.0 |
| MND1 | 5187.0 |
| H2BC5 | 5130.0 |
| RBL2 | 5110.0 |
| NUP107 | 5069.0 |
| CDKN1A | 5054.0 |
| CEP152 | 5016.0 |
| DAXX | 4994.0 |
| H4C6 | 4952.0 |
| TERF2 | 4935.0 |
| RCC2 | 4920.0 |
| PPP6C | 4860.0 |
| MCM3 | 4832.0 |
| PCNA | 4821.0 |
| NUP88 | 4788.0 |
| CDC20 | 4753.0 |
| H3C4 | 4718.0 |
| RPS27 | 4711.0 |
| SPC25 | 4707.0 |
| CSNK2A1 | 4697.0 |
| NUP133 | 4676.0 |
| ANAPC5 | 4671.0 |
| GINS1 | 4665.0 |
| H2BC3 | 4658.0 |
| YWHAZ | 4655.0 |
| TUBGCP2 | 4639.0 |
| H4C13 | 4630.0 |
| CEP135 | 4607.0 |
| BRIP1 | 4606.0 |
| ATM | 4600.0 |
| ORC2 | 4592.0 |
| H4C11 | 4553.0 |
| FBXO5 | 4493.0 |
| KIF18A | 4448.0 |
| MAD2L1 | 4439.0 |
| STAG3 | 4402.0 |
| KPNB1 | 4376.0 |
| NSL1 | 4358.0 |
| HMMR | 4352.0 |
| PSMF1 | 4311.0 |
| CCND2 | 4278.0 |
| UBE2I | 4265.0 |
| CDT1 | 4263.0 |
| NME7 | 4251.0 |
| BLM | 4237.0 |
| PMF1 | 4232.0 |
| PSMD1 | 4227.0 |
| PSME3 | 4172.0 |
| CENPE | 4143.0 |
| CSNK2A2 | 4122.0 |
| PSMC2 | 4088.0 |
| TNPO1 | 4083.0 |
| CENPS | 4026.0 |
| E2F5 | 4024.0 |
| SMC2 | 3987.0 |
| CDCA8 | 3983.0 |
| H2BC10 | 3947.0 |
| PSMA8 | 3923.0 |
| POLR2A | 3916.0 |
| PSMA7 | 3903.0 |
| PSME1 | 3866.0 |
| PSMA3 | 3850.0 |
| HSP90AB1 | 3811.0 |
| FKBP6 | 3806.0 |
| H4C4 | 3785.0 |
| NUP205 | 3738.0 |
| CABLES1 | 3701.0 |
| TOP2A | 3676.0 |
| MAPRE1 | 3644.0 |
| EXO1 | 3595.0 |
| CCNA1 | 3593.0 |
| PRKCB | 3548.0 |
| SKP1 | 3534.0 |
| PRKACA | 3519.0 |
| CEP78 | 3480.0 |
| TEN1 | 3460.0 |
| PSMB9 | 3459.0 |
| CDKN2C | 3429.0 |
| CHEK2 | 3413.0 |
| RCC1 | 3406.0 |
| PPP2R5C | 3398.0 |
| HUS1 | 3387.0 |
| TFDP2 | 3339.0 |
| WAPL | 3291.0 |
| H2BC17 | 3276.0 |
| CENPF | 3253.0 |
| STN1 | 3217.0 |
| CCNE2 | 3190.0 |
| CSNK1D | 3179.0 |
| POLR2E | 3177.0 |
| RFC2 | 3136.0 |
| ACTR1A | 3117.0 |
| SET | 3096.0 |
| NOP10 | 3084.0 |
| POLE4 | 3064.0 |
| CDC27 | 3049.0 |
| H3C6 | 3009.0 |
| PSMC4 | 3004.0 |
| NUF2 | 2983.0 |
| PSMC3 | 2960.0 |
| H2AC6 | 2946.0 |
| PRIM1 | 2888.0 |
| NUP42 | 2844.0 |
| HAUS8 | 2809.0 |
| BRCA2 | 2796.0 |
| NUP93 | 2792.0 |
| MCM7 | 2717.0 |
| NUP58 | 2703.0 |
| H3C8 | 2699.0 |
| YWHAH | 2697.0 |
| PHLDA1 | 2691.0 |
| RANBP2 | 2651.0 |
| MLH3 | 2552.0 |
| PPME1 | 2529.0 |
| SEM1 | 2517.0 |
| H2AC4 | 2379.0 |
| UBE2N | 2342.0 |
| CDC26 | 2306.0 |
| PPP2CA | 2292.0 |
| CHMP6 | 2240.0 |
| IST1 | 2232.0 |
| HAUS2 | 2201.0 |
| CHMP4A | 2193.0 |
| MCM8 | 2177.0 |
| CCNB2 | 2043.0 |
| H3-4 | 2030.0 |
| POLR2D | 2025.0 |
| RAB1A | 1997.0 |
| ORC4 | 1976.0 |
| ANAPC15 | 1950.0 |
| CDC23 | 1927.0 |
| PPP1R12A | 1921.0 |
| BUB3 | 1906.0 |
| FBXL18 | 1900.0 |
| CENPJ | 1883.0 |
| SYCE2 | 1829.0 |
| TINF2 | 1779.0 |
| CEP250 | 1760.0 |
| SGO1 | 1729.0 |
| CENPK | 1710.0 |
| CHMP3 | 1707.0 |
| TEX15 | 1494.0 |
| HAUS5 | 1481.0 |
| CDC7 | 1479.0 |
| MYBL2 | 1460.0 |
| CCP110 | 1440.0 |
| H3C2 | 1438.0 |
| HSP90AA1 | 1355.0 |
| H2BC11 | 1338.0 |
| LIN9 | 1238.0 |
| NCAPH | 1206.0 |
| HAUS3 | 1201.0 |
| BRCA1 | 1120.0 |
| RPA2 | 1117.0 |
| PPP2R2A | 1071.0 |
| ANKLE2 | 983.0 |
| CEP63 | 968.0 |
| CENPW | 943.0 |
| TUBA4A | 938.0 |
| MZT2A | 915.0 |
| RFC4 | 824.0 |
| CDC16 | 754.0 |
| YWHAE | 744.0 |
| ENSA | 708.0 |
| TUBA4B | 650.0 |
| NDEL1 | 641.0 |
| SDCCAG8 | 622.0 |
| PSMD11 | 620.0 |
| REC8 | 524.0 |
| CNEP1R1 | 520.0 |
| H2AX | 499.0 |
| PCBP4 | 475.0 |
| NEK7 | 461.0 |
| TUBGCP6 | 457.0 |
| PDS5A | 449.0 |
| PSMB8 | 447.0 |
| POLD2 | 347.0 |
| HDAC1 | 346.0 |
| YWHAQ | 336.0 |
| CHMP7 | 308.0 |
| RAD17 | 283.0 |
| TOP3A | 244.0 |
| H2BC15 | 240.0 |
| DYNC1LI1 | 233.0 |
| SMARCA5 | 228.0 |
| MDM2 | 219.0 |
| BTRC | 216.0 |
| DCTN3 | 114.0 |
| POLE2 | 60.0 |
| UIMC1 | 46.0 |
| RAD9B | 45.0 |
| ORC3 | 36.0 |
| FZR1 | 16.0 |
| MIS12 | 15.0 |
| MCM6 | 2.0 |
| POLA2 | -22.0 |
| FKBPL | -24.0 |
| RFC5 | -81.0 |
| PSMA2 | -85.0 |
| PPP2R5A | -152.0 |
| PCM1 | -170.0 |
| HAUS1 | -189.0 |
| DYNC1I1 | -202.0 |
| NSD2 | -277.0 |
| ANAPC4 | -310.0 |
| RMI1 | -315.0 |
| KIF20A | -330.0 |
| NUP98 | -351.0 |
| H2AZ1 | -360.0 |
| SYNE1 | -400.0 |
| HSPA2 | -408.0 |
| DYNC1I2 | -440.0 |
| DIDO1 | -454.0 |
| CHMP2A | -462.0 |
| HJURP | -468.0 |
| UBE2V2 | -500.0 |
| SUN2 | -507.0 |
| H3C3 | -546.0 |
| COP1 | -554.0 |
| TUBB1 | -584.0 |
| ORC5 | -617.0 |
| RBL1 | -621.0 |
| SYCE1 | -623.0 |
| POT1 | -662.0 |
| E2F6 | -673.0 |
| H2AC20 | -674.0 |
| HAUS4 | -693.0 |
| MNAT1 | -717.0 |
| OPTN | -719.0 |
| GMNN | -730.0 |
| RAB2A | -745.0 |
| CEP41 | -791.0 |
| MAPK1 | -857.0 |
| PSMD14 | -865.0 |
| CENPO | -914.0 |
| GINS4 | -959.0 |
| PSMD6 | -961.0 |
| CCND1 | -962.0 |
| FBXW11 | -964.0 |
| NEK6 | -969.0 |
| POLR2L | -971.0 |
| SPDL1 | -977.0 |
| AKAP9 | -1032.0 |
| PPP6R3 | -1037.0 |
| ANAPC1 | -1043.0 |
| XPO1 | -1083.0 |
| CHMP4B | -1102.0 |
| CEP72 | -1128.0 |
| CDK6 | -1199.0 |
| PSMB7 | -1294.0 |
| LMNB1 | -1316.0 |
| PTTG1 | -1320.0 |
| BLZF1 | -1356.0 |
| UBE2S | -1361.0 |
| MIS18A | -1379.0 |
| H2BC6 | -1396.0 |
| NDC1 | -1433.0 |
| LIG1 | -1478.0 |
| ESCO1 | -1480.0 |
| ACD | -1494.5 |
| RTEL1 | -1529.0 |
| MAX | -1557.0 |
| NUDC | -1567.0 |
| PPP2R2D | -1687.0 |
| SUN1 | -1697.0 |
| SPO11 | -1864.0 |
| NUP188 | -1877.0 |
| YWHAG | -1887.0 |
| DMC1 | -1893.0 |
| SMC4 | -1946.0 |
| PHF20 | -1999.0 |
| CLASP1 | -2048.0 |
| H2BC4 | -2094.0 |
| PPP2R1A | -2107.0 |
| H2BC12 | -2115.0 |
| CEP290 | -2146.0 |
| TFDP1 | -2156.0 |
| CENPN | -2163.0 |
| CLASP2 | -2170.0 |
| ANKRD28 | -2173.0 |
| TP53BP1 | -2175.0 |
| ZWILCH | -2190.0 |
| GORASP2 | -2197.0 |
| TUBB | -2261.0 |
| PSMB10 | -2290.0 |
| CTDNEP1 | -2338.0 |
| E2F3 | -2343.0 |
| EP300 | -2354.0 |
| ODF2 | -2377.0 |
| PSMB6 | -2408.0 |
| JAK2 | -2410.0 |
| CUL1 | -2437.0 |
| LPIN2 | -2453.0 |
| CDK11B | -2458.0 |
| MZT1 | -2477.0 |
| AKT2 | -2480.0 |
| PPP2R5E | -2509.0 |
| SUMO1 | -2534.0 |
| UBE2C | -2539.0 |
| PIAS4 | -2542.0 |
| MSH5 | -2544.0 |
| AKT1 | -2548.0 |
| PSMD9 | -2570.0 |
| MYC | -2593.0 |
| UBE2E1 | -2647.0 |
| TYMS | -2661.0 |
| SFI1 | -2689.0 |
| CLSPN | -2700.0 |
| NCAPG2 | -2771.0 |
| AAAS | -2839.0 |
| WRN | -2909.0 |
| RUVBL1 | -2958.0 |
| HERC2 | -3058.0 |
| CDC25B | -3069.0 |
| CEP57 | -3092.0 |
| PPP1CC | -3102.0 |
| TERF1 | -3138.0 |
| LCMT1 | -3145.0 |
| LEMD2 | -3163.0 |
| PRKCA | -3175.0 |
| PRKAR2B | -3186.0 |
| POLR2B | -3234.0 |
| CHMP2B | -3280.0 |
| GORASP1 | -3300.0 |
| MSH4 | -3306.0 |
| STAG1 | -3331.0 |
| WEE1 | -3415.0 |
| NUP153 | -3416.0 |
| SPAST | -3426.0 |
| SPC24 | -3429.0 |
| NCAPD3 | -3452.0 |
| ORC6 | -3467.0 |
| DHFR | -3474.0 |
| CCNA2 | -3495.0 |
| RAE1 | -3503.0 |
| DYNLL1 | -3541.0 |
| GTSE1 | -3549.0 |
| EML4 | -3716.0 |
| RMI2 | -3754.0 |
| UBA52 | -3755.0 |
| PKMYT1 | -3762.0 |
| ANAPC7 | -3780.0 |
| LPIN1 | -3821.0 |
| ALMS1 | -3856.0 |
| NBN | -3893.0 |
| TERF2IP | -3905.0 |
| FBXL7 | -3927.0 |
| RANGAP1 | -3961.0 |
| RFC1 | -3990.0 |
| AJUBA | -4043.0 |
| POM121C | -4045.0 |
| CDKN1C | -4120.0 |
| SRC | -4161.0 |
| TUBGCP5 | -4190.0 |
| NEDD1 | -4195.0 |
| PLK4 | -4251.0 |
| E2F2 | -4314.0 |
| TUBA1C | -4357.0 |
| RAD51 | -4393.0 |
| CEP43 | -4402.0 |
| LIN54 | -4429.0 |
| BORA | -4440.0 |
| TUBA1B | -4469.0 |
| ANAPC16 | -4502.0 |
| ATR | -4506.0 |
| PSMB5 | -4687.0 |
| CEP192 | -4704.0 |
| SKP2 | -4745.0 |
| POLR2F | -4762.0 |
| CNTRL | -4773.0 |
| SYCP3 | -4865.0 |
| H2BC9 | -4907.5 |
| H3C7 | -4907.5 |
| CDK7 | -4917.0 |
| H4C5 | -4941.0 |
| RFC3 | -4967.0 |
| RRM2 | -4995.0 |
| SYCP2 | -5084.0 |
| RSF1 | -5135.0 |
| VPS4A | -5196.0 |
| PSMD7 | -5198.0 |
| ATRIP | -5201.0 |
| RNF168 | -5219.0 |
| CHTF18 | -5233.0 |
| TAOK1 | -5237.0 |
| TUBA3D | -5264.0 |
| INCENP | -5274.0 |
| CEP76 | -5319.0 |
| PSMD4 | -5337.0 |
| UBE2D1 | -5394.0 |
| DCTN1 | -5418.0 |
| POLD3 | -5419.0 |
| POLR2C | -5430.0 |
| MAPK3 | -5444.0 |
| NUP214 | -5472.0 |
| CEP131 | -5479.0 |
| AKT3 | -5586.0 |
| SEC13 | -5670.0 |
| CDK11A | -5719.0 |
| H2BC21 | -5773.0 |
| TERT | -5784.0 |
| TOPBP1 | -5800.0 |
| NDE1 | -5839.0 |
| PSMB1 | -5858.0 |
| SMC1B | -5957.0 |
| VRK1 | -5980.0 |
| MCPH1 | -5981.0 |
| MAD1L1 | -6006.0 |
| GSK3B | -6007.0 |
| POLR2J | -6011.0 |
| DYNC1H1 | -6092.0 |
| BABAM2 | -6094.0 |
| PRIM2 | -6159.0 |
| CDK1 | -6160.0 |
| GOLGA2 | -6181.0 |
| NUP50 | -6183.0 |
| TEX12 | -6245.0 |
| POLR2H | -6261.0 |
| CENPU | -6349.0 |
| PPP1R12B | -6357.0 |
| RAD50 | -6431.0 |
| CDK5RAP2 | -6528.0 |
| TMPO | -6633.0 |
| NUP210 | -6637.0 |
| H2BC26 | -6695.0 |
| E2F4 | -6771.0 |
| NUMA1 | -6909.0 |
| SKA1 | -6910.0 |
| MAU2 | -6927.0 |
| KIF2A | -6979.0 |
| CDCA5 | -7077.0 |
| NUP160 | -7169.0 |
| PPP2CB | -7216.0 |
| NUP62 | -7266.0 |
| TUBGCP3 | -7341.0 |
| ARPP19 | -7351.0 |
| CDC6 | -7443.0 |
| PCNT | -7476.0 |
| CSNK1E | -7527.0 |
| PTK6 | -7557.0 |
| TUBB4A | -7633.0 |
| CEP164 | -7712.0 |
| PSMD8 | -7723.0 |
| NCAPH2 | -7762.0 |
| CENPP | -7911.0 |
| NIPBL | -7970.0 |
| TUBGCP4 | -7988.0 |
| GINS3 | -7990.0 |
| TUBA1A | -8056.0 |
| SYNE2 | -8073.0 |
| RPA3 | -8086.0 |
| ZNF385A | -8149.0 |
| NINL | -8186.0 |
| PPP2R1B | -8245.0 |
| POLR2G | -8279.0 |
| ABL1 | -8289.0 |
| POLE | -8297.0 |
| H2AC14 | -8606.0 |
| HAUS6 | -8616.0 |
| CENPH | -8704.0 |
| H2BC14 | -8730.0 |
| OIP5 | -8739.0 |
| MZT2B | -8774.0 |
| KIF2B | -8857.0 |
| LPIN3 | -8997.0 |
| TPR | -9043.0 |
| H4C9 | -9282.0 |
| SFN | -9368.0 |
| TUBB2A | -9511.0 |
| PSMD5 | -9524.0 |
| TK1 | -9564.0 |
| CCNE1 | -9930.0 |
| CENPA | -9945.0 |
| SYCP1 | -10004.0 |
| TUBA3C | -10220.0 |
| H2AC18 | -10224.5 |
| H2AC19 | -10224.5 |
| TUBA3E | -10574.0 |
REACTOME_INNATE_IMMUNE_SYSTEM
| 227 | |
|---|---|
| set | REACTOME_INNATE_IMMUNE_SYSTEM |
| setSize | 1002 |
| pANOVA | 7.58e-06 |
| s.dist | 0.0836 |
| p.adjustANOVA | 0.000566 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RNASE2 | 11054 |
| IFNA13 | 11049 |
| TYROBP | 10985 |
| MCEMP1 | 10982 |
| RAB3D | 10963 |
| IFNA1 | 10960 |
| RAC2 | 10947 |
| LRG1 | 10943 |
| PI3 | 10905 |
| PLD4 | 10884 |
| SFTPA1 | 10869 |
| GMFG | 10846 |
| DEFB114 | 10818 |
| CEACAM8 | 10770 |
| RNASE7 | 10701 |
| CGAS | 10680 |
| MUC1 | 10668 |
| LAT2 | 10642 |
| CD14 | 10564 |
| CEACAM1 | 10549 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RNASE2 | 11054.0 |
| IFNA13 | 11049.0 |
| TYROBP | 10985.0 |
| MCEMP1 | 10982.0 |
| RAB3D | 10963.0 |
| IFNA1 | 10960.0 |
| RAC2 | 10947.0 |
| LRG1 | 10943.0 |
| PI3 | 10905.0 |
| PLD4 | 10884.0 |
| SFTPA1 | 10869.0 |
| GMFG | 10846.0 |
| DEFB114 | 10818.0 |
| CEACAM8 | 10770.0 |
| RNASE7 | 10701.0 |
| CGAS | 10680.0 |
| MUC1 | 10668.0 |
| LAT2 | 10642.0 |
| CD14 | 10564.0 |
| CEACAM1 | 10549.0 |
| PGLYRP3 | 10447.0 |
| DEFB125 | 10415.0 |
| FGR | 10409.0 |
| GCA | 10406.0 |
| POLR2K | 10402.0 |
| TICAM1 | 10386.0 |
| SYNGR1 | 10358.0 |
| PTPN11 | 10353.0 |
| PRG3 | 10327.0 |
| PSMD12 | 10325.0 |
| S100B | 10265.0 |
| POLR3GL | 10262.0 |
| RNF135 | 10242.0 |
| MUC20 | 10213.0 |
| SERPINB3 | 10211.0 |
| TBC1D10C | 10191.0 |
| ADGRE3 | 10171.0 |
| CXCL1 | 10160.0 |
| ATP6V1G2 | 10077.0 |
| S100A11 | 10074.0 |
| TRIM21 | 10071.0 |
| TMC6 | 10033.0 |
| CD180 | 10010.0 |
| PTX3 | 9998.0 |
| PLAC8 | 9983.0 |
| ACTG1 | 9978.0 |
| PSMC6 | 9977.0 |
| FTL | 9939.0 |
| SRP14 | 9909.0 |
| ATP6V0E1 | 9908.0 |
| CTSZ | 9906.0 |
| PYCARD | 9904.0 |
| CLEC12A | 9861.0 |
| PSMB3 | 9858.0 |
| DCD | 9840.0 |
| TLR2 | 9837.0 |
| CCR2 | 9813.0 |
| TLR9 | 9810.0 |
| TLR4 | 9756.0 |
| MS4A2 | 9748.0 |
| P2RX1 | 9684.0 |
| GPI | 9649.0 |
| IRAK3 | 9647.0 |
| ACTB | 9643.0 |
| CFD | 9630.0 |
| RHOG | 9610.0 |
| JUN | 9609.0 |
| TIFA | 9606.0 |
| C1QC | 9579.0 |
| UBA7 | 9564.0 |
| RAF1 | 9510.0 |
| ATP6V0E2 | 9509.0 |
| VAV1 | 9507.0 |
| LILRB2 | 9490.0 |
| SFTPD | 9481.0 |
| UBC | 9476.0 |
| UBE2V1 | 9459.0 |
| TREM1 | 9402.0 |
| RHOF | 9394.0 |
| DEFB127 | 9392.0 |
| DSN1 | 9391.0 |
| CXCR1 | 9368.0 |
| CLEC4A | 9354.0 |
| CXCR2 | 9339.0 |
| WASF1 | 9310.0 |
| CHIT1 | 9309.0 |
| DUSP3 | 9307.0 |
| C4BPA | 9284.0 |
| LY96 | 9278.0 |
| SLC15A4 | 9259.0 |
| SERPINB1 | 9254.0 |
| PRTN3 | 9235.0 |
| DDOST | 9201.0 |
| S100P | 9175.0 |
| TLR1 | 9115.0 |
| LCP2 | 9106.0 |
| ORMDL3 | 9096.0 |
| SNAP29 | 9070.0 |
| KLRD1 | 9067.0 |
| LCK | 9065.0 |
| RNF125 | 9013.0 |
| CD53 | 8995.0 |
| SYK | 8993.0 |
| GM2A | 8980.0 |
| TXN | 8969.0 |
| TNFRSF1B | 8954.0 |
| PROS1 | 8952.0 |
| FTH1 | 8933.0 |
| ISG15 | 8922.0 |
| MAPK12 | 8809.0 |
| CARD9 | 8789.0 |
| ATP6V0D2 | 8747.0 |
| ECSIT | 8742.0 |
| CREG1 | 8741.0 |
| MAPK14 | 8739.0 |
| CSNK2B | 8721.0 |
| PPP2R5D | 8711.0 |
| ICAM3 | 8703.0 |
| DUSP4 | 8698.0 |
| NCF2 | 8692.0 |
| PSME2 | 8685.0 |
| OSCAR | 8684.0 |
| WASF2 | 8672.0 |
| ATP6V1F | 8669.0 |
| LYN | 8661.0 |
| POLR1C | 8652.0 |
| SHC1 | 8640.0 |
| ATP6V1G1 | 8624.0 |
| CD55 | 8607.0 |
| ATP6V1C1 | 8602.0 |
| VAT1 | 8586.0 |
| SNAP23 | 8577.0 |
| PGLYRP2 | 8555.0 |
| CD93 | 8554.0 |
| LAMTOR2 | 8526.0 |
| OLR1 | 8522.0 |
| UNC13D | 8476.0 |
| STAT6 | 8465.0 |
| TLR6 | 8450.0 |
| CTSV | 8398.0 |
| UBA3 | 8341.0 |
| ATAD3B | 8339.0 |
| RAB37 | 8300.0 |
| S100A8 | 8296.0 |
| ATP6V1E1 | 8281.0 |
| RAB14 | 8239.0 |
| ADAM8 | 8237.0 |
| NFKBIB | 8232.0 |
| CD63 | 8228.0 |
| LILRB3 | 8205.0 |
| PSMB4 | 8180.0 |
| DEFB118 | 8176.0 |
| DUSP7 | 8174.0 |
| PRKACG | 8167.0 |
| LGMN | 8149.0 |
| DOK3 | 8140.0 |
| GRB2 | 8138.0 |
| PGLYRP4 | 8127.0 |
| CTSA | 8121.0 |
| TP53 | 8108.0 |
| COTL1 | 8096.0 |
| CLEC5A | 8093.0 |
| PTPN6 | 8069.0 |
| EPPIN-WFDC6 | 8067.0 |
| ATP6V0A1 | 8024.0 |
| POLR3H | 8006.0 |
| C2 | 7970.0 |
| CR2 | 7961.0 |
| TUBB4B | 7956.0 |
| RAB3A | 7925.0 |
| ARPC3 | 7914.0 |
| PSMD13 | 7901.0 |
| TXNIP | 7855.0 |
| EPPIN | 7848.0 |
| GLIPR1 | 7830.0 |
| FADD | 7817.0 |
| TLR3 | 7807.0 |
| IFI16 | 7802.0 |
| RAB5C | 7798.0 |
| CCT8 | 7787.0 |
| CFL1 | 7777.0 |
| NCR2 | 7750.0 |
| VRK3 | 7733.0 |
| PSME4 | 7705.0 |
| NPC2 | 7691.0 |
| MAP2K3 | 7685.0 |
| UBB | 7674.0 |
| PSMB2 | 7641.0 |
| PGM2 | 7637.0 |
| AMPD3 | 7595.0 |
| CEACAM6 | 7587.0 |
| GOLGA7 | 7563.0 |
| POLR3G | 7518.0 |
| HSPA8 | 7490.0 |
| WIPF2 | 7436.0 |
| TRAPPC1 | 7379.0 |
| RAB31 | 7366.0 |
| PSMB11 | 7359.0 |
| PLAUR | 7349.0 |
| IFNA7 | 7302.0 |
| B2M | 7278.0 |
| CASP10 | 7274.0 |
| HPSE | 7248.0 |
| POLR3K | 7245.0 |
| COPB1 | 7205.0 |
| RAB4B | 7197.0 |
| PSMA6 | 7190.0 |
| PRCP | 7161.0 |
| DNM1 | 7157.0 |
| PRG2 | 7148.0 |
| NCKAP1L | 7142.0 |
| GGH | 7131.0 |
| RPS27A | 7120.0 |
| DEFB115 | 7112.0 |
| NFAM1 | 7108.0 |
| CLU | 7037.0 |
| MIF | 7025.0 |
| REG3A | 7023.0 |
| PSMA1 | 7018.0 |
| SERPINB12 | 7014.0 |
| NLRP3 | 7003.0 |
| TOMM70 | 6987.0 |
| LAIR1 | 6982.0 |
| CAND1 | 6925.0 |
| PIK3R2 | 6906.0 |
| IRAG2 | 6905.0 |
| ARPC1B | 6892.0 |
| FCAR | 6890.0 |
| CKAP4 | 6887.0 |
| PGLYRP1 | 6878.0 |
| NKIRAS2 | 6833.0 |
| ATP6V1B2 | 6805.0 |
| TICAM2 | 6800.0 |
| BRI3 | 6794.0 |
| PPP3R1 | 6782.0 |
| CLEC6A | 6778.0 |
| PELI3 | 6746.0 |
| YPEL5 | 6680.0 |
| PSMD3 | 6672.0 |
| C5AR2 | 6664.0 |
| POLR3F | 6578.0 |
| MAP2K7 | 6542.0 |
| CD19 | 6535.0 |
| CD36 | 6523.0 |
| HCK | 6499.0 |
| BCL10 | 6498.0 |
| MS4A3 | 6495.0 |
| TNFAIP3 | 6445.0 |
| CD3G | 6321.0 |
| HMGB1 | 6295.0 |
| RNASE6 | 6294.0 |
| NCK1 | 6286.0 |
| EEA1 | 6270.0 |
| IFNA14 | 6151.0 |
| TMBIM1 | 6149.0 |
| DPP7 | 6148.0 |
| SIGLEC9 | 6137.0 |
| VNN1 | 6113.0 |
| MAP3K14 | 6091.0 |
| IKBKE | 6071.0 |
| IFNA2 | 6068.0 |
| CREB1 | 6047.0 |
| FCN3 | 6035.0 |
| ILF2 | 5988.0 |
| CYBA | 5941.0 |
| BCL2 | 5940.0 |
| LTA4H | 5833.0 |
| GRAP2 | 5829.0 |
| ALAD | 5817.0 |
| PYGL | 5800.0 |
| CASP9 | 5797.0 |
| TIRAP | 5762.0 |
| STK10 | 5721.0 |
| PSMC1 | 5715.0 |
| IRAK2 | 5710.0 |
| CPNE3 | 5693.0 |
| BPIFB1 | 5692.0 |
| KCMF1 | 5685.0 |
| IRF3 | 5649.0 |
| TIMP2 | 5648.0 |
| PSMD2 | 5624.0 |
| MRE11 | 5620.0 |
| CPB2 | 5609.0 |
| UBE2K | 5606.0 |
| DEFB136 | 5586.0 |
| DEFB126 | 5583.0 |
| SEMG1 | 5563.0 |
| B4GALT1 | 5557.0 |
| POLR3A | 5545.0 |
| MUC12 | 5526.0 |
| PRDX6 | 5512.0 |
| CTSD | 5503.0 |
| CHUK | 5500.0 |
| ATP6V1A | 5492.0 |
| BCL2L1 | 5479.0 |
| RASGRP4 | 5440.0 |
| NFKBIA | 5436.0 |
| IRAK4 | 5412.0 |
| IFNA8 | 5410.0 |
| ARMC8 | 5408.0 |
| SIGLEC15 | 5394.0 |
| MYO1C | 5390.0 |
| HLA-E | 5384.0 |
| ITGAM | 5378.0 |
| CAPZA1 | 5374.0 |
| IFNA16 | 5367.0 |
| PSMA5 | 5362.0 |
| PSAP | 5358.0 |
| VCL | 5337.0 |
| F2 | 5247.0 |
| PSMA4 | 5246.0 |
| GDI2 | 5245.0 |
| CD300LB | 5218.0 |
| BIN2 | 5212.0 |
| RBSN | 5197.0 |
| PSMC5 | 5193.0 |
| CLEC4C | 5138.0 |
| IMPDH2 | 5096.0 |
| CTSC | 5095.0 |
| PAFAH1B2 | 5092.0 |
| ATP6V0A2 | 5026.0 |
| NAPRT | 5010.0 |
| MAN2B1 | 4969.0 |
| IDH1 | 4950.0 |
| SLC2A3 | 4924.0 |
| HP | 4864.0 |
| MYH9 | 4847.0 |
| GRN | 4817.0 |
| KRAS | 4814.0 |
| DUSP6 | 4740.0 |
| ALDOA | 4710.0 |
| CAP1 | 4706.0 |
| C1orf35 | 4695.0 |
| C4BPB | 4687.0 |
| SNAP25 | 4681.0 |
| AP1M1 | 4662.0 |
| CCT2 | 4643.0 |
| RAB24 | 4623.0 |
| XRCC6 | 4619.0 |
| PTPRJ | 4578.0 |
| POLR3B | 4514.0 |
| ATP6V0C | 4507.0 |
| PCBP2 | 4487.0 |
| RPS6KA1 | 4484.0 |
| HK3 | 4453.0 |
| FYN | 4444.0 |
| GSN | 4432.0 |
| KPNB1 | 4376.0 |
| FCN2 | 4356.0 |
| ATP6V1D | 4345.0 |
| ITGB2 | 4336.0 |
| MAP3K8 | 4314.0 |
| LRRFIP1 | 4313.0 |
| PSMF1 | 4311.0 |
| SOCS1 | 4294.0 |
| NEU1 | 4293.0 |
| PSMD1 | 4227.0 |
| APP | 4173.0 |
| PSME3 | 4172.0 |
| PLD2 | 4164.0 |
| MAPKAPK2 | 4162.0 |
| CD300A | 4132.0 |
| ERP44 | 4125.0 |
| RNF216 | 4109.0 |
| PSMC2 | 4088.0 |
| FABP5 | 4057.0 |
| MME | 4038.0 |
| SVIP | 4032.0 |
| LIMK1 | 3982.0 |
| PFKL | 3974.0 |
| FCER1A | 3965.0 |
| CAPZA2 | 3961.0 |
| PSMA8 | 3923.0 |
| PSMA7 | 3903.0 |
| PSME1 | 3866.0 |
| PSMA3 | 3850.0 |
| HSP90AB1 | 3811.0 |
| TOM1 | 3798.0 |
| HERC5 | 3783.0 |
| PPBP | 3761.0 |
| ARPC5 | 3724.0 |
| CDC42 | 3714.0 |
| MYO5A | 3683.0 |
| UBE2D2 | 3677.0 |
| DSP | 3665.0 |
| ALDOC | 3623.0 |
| MMP25 | 3614.0 |
| ATF2 | 3606.0 |
| TEC | 3601.0 |
| SOS1 | 3578.0 |
| SIKE1 | 3566.0 |
| SKP1 | 3534.0 |
| ANO6 | 3532.0 |
| PRKACA | 3519.0 |
| SLPI | 3517.0 |
| CAPN1 | 3476.0 |
| PSMB9 | 3459.0 |
| MAPK9 | 3453.0 |
| NHLRC3 | 3444.0 |
| ELMO1 | 3405.0 |
| NF2 | 3384.0 |
| MAPK13 | 3377.0 |
| CD59 | 3373.0 |
| TMEM63A | 3363.0 |
| ARPC4 | 3357.0 |
| ATP6V1B1 | 3349.0 |
| POLR1D | 3345.0 |
| TCIRG1 | 3340.0 |
| C3AR1 | 3335.0 |
| STING1 | 3310.0 |
| ENPP4 | 3255.0 |
| HMOX2 | 3213.0 |
| NFATC3 | 3198.0 |
| UNC93B1 | 3194.0 |
| POLR2E | 3177.0 |
| HEBP2 | 3173.0 |
| CTSG | 3167.0 |
| PGM1 | 3161.0 |
| GHDC | 3137.0 |
| TAX1BP1 | 3135.0 |
| CASP8 | 3129.0 |
| PTK2 | 3128.0 |
| ATP6V1E2 | 3127.0 |
| KCNAB2 | 3083.0 |
| P2RX7 | 3074.0 |
| MASP1 | 3069.0 |
| PSMC4 | 3004.0 |
| RAB5B | 2980.0 |
| UBE2D3 | 2976.0 |
| PSMC3 | 2960.0 |
| LILRA3 | 2920.0 |
| CLEC7A | 2901.0 |
| SLC44A2 | 2856.0 |
| PNP | 2842.0 |
| RAB6A | 2791.0 |
| MAP2K1 | 2768.0 |
| RELB | 2738.0 |
| MYO9B | 2714.0 |
| AGA | 2675.0 |
| BPI | 2605.0 |
| SIRPA | 2593.0 |
| CPPED1 | 2591.0 |
| TOLLIP | 2585.0 |
| TAB1 | 2578.0 |
| FGB | 2567.0 |
| SEM1 | 2517.0 |
| PAK2 | 2407.0 |
| UBE2N | 2342.0 |
| MEF2C | 2335.0 |
| CHGA | 2322.0 |
| TNIP2 | 2319.0 |
| TMEM179B | 2317.0 |
| SERPINB6 | 2314.0 |
| ITCH | 2310.0 |
| PPP2CA | 2292.0 |
| PIK3CB | 2284.0 |
| FOS | 2247.0 |
| MUC3A | 2234.0 |
| IST1 | 2232.0 |
| MYD88 | 2230.0 |
| ACTR3 | 2131.0 |
| DGAT1 | 2100.0 |
| DNAJC3 | 2083.0 |
| ABI1 | 2081.0 |
| C3 | 2058.0 |
| RAB10 | 2050.0 |
| GAB2 | 2042.0 |
| SURF4 | 2034.0 |
| CTSK | 2011.0 |
| AGER | 1968.0 |
| SLCO4C1 | 1918.0 |
| IKBIP | 1872.0 |
| MAPKAPK3 | 1801.0 |
| NLRC5 | 1742.0 |
| LAMTOR1 | 1723.0 |
| LY86 | 1722.0 |
| IMPDH1 | 1715.0 |
| MAVS | 1682.0 |
| MASP2 | 1631.0 |
| ITPR2 | 1625.0 |
| APEH | 1622.0 |
| CRCP | 1592.0 |
| CDA | 1537.0 |
| PIK3CA | 1515.0 |
| GZMM | 1480.0 |
| SLC2A5 | 1477.0 |
| CAB39 | 1463.0 |
| FGL2 | 1457.0 |
| ITGAL | 1423.0 |
| ACTR10 | 1402.0 |
| WIPF1 | 1400.0 |
| PSEN1 | 1368.0 |
| HSP90AA1 | 1355.0 |
| TBK1 | 1331.0 |
| RNASE3 | 1316.0 |
| RAB27A | 1310.0 |
| RAB18 | 1309.0 |
| C5 | 1286.0 |
| PRKACB | 1268.0 |
| IQGAP2 | 1233.0 |
| PIK3R1 | 1134.0 |
| IFIH1 | 1116.0 |
| MUC6 | 1067.0 |
| LRRC14 | 1044.0 |
| IQGAP1 | 988.0 |
| LBP | 965.0 |
| CD81 | 962.0 |
| MUC16 | 959.0 |
| VAV3 | 933.0 |
| SERPINB10 | 909.0 |
| IGF2R | 895.0 |
| DEFB134 | 869.0 |
| AAMP | 868.0 |
| AGPAT2 | 859.0 |
| ARL8A | 848.0 |
| SIGIRR | 821.0 |
| ASAH1 | 808.0 |
| CD68 | 803.0 |
| DEFA5 | 801.0 |
| DSC1 | 798.0 |
| MANBA | 792.0 |
| PA2G4 | 729.0 |
| IKBKB | 710.0 |
| XRCC5 | 699.0 |
| MNDA | 645.0 |
| ROCK1 | 627.0 |
| PSMD11 | 620.0 |
| PIN1 | 606.0 |
| EEF2 | 562.0 |
| TRIM25 | 479.0 |
| DEFB129 | 468.0 |
| PSMB8 | 447.0 |
| BPIFB6 | 416.0 |
| A1BG | 391.0 |
| AHSG | 366.0 |
| HSP90B1 | 354.0 |
| LPCAT1 | 335.0 |
| GSTP1 | 326.0 |
| ANPEP | 291.0 |
| HEXB | 278.0 |
| DYNC1LI1 | 233.0 |
| BTRC | 216.0 |
| POLR3D | 197.0 |
| LAT | 180.0 |
| ARPC2 | 177.0 |
| DEFB121 | 175.0 |
| SDCBP | 163.0 |
| PKM | 139.0 |
| ATP8A1 | 137.0 |
| STBD1 | 125.0 |
| MALT1 | 100.0 |
| PRSS3 | 74.0 |
| GUSB | 57.0 |
| DEFB119 | 43.0 |
| CNPY3 | 29.0 |
| ARSB | -12.0 |
| HGSNAT | -32.0 |
| PLD3 | -42.0 |
| RAP2B | -48.0 |
| ALDH3B1 | -73.0 |
| PSMA2 | -85.0 |
| DBNL | -91.0 |
| ARSA | -98.0 |
| SLC11A1 | -133.0 |
| COMMD3 | -141.0 |
| ADA2 | -154.0 |
| TCN1 | -159.0 |
| NKIRAS1 | -185.0 |
| CD177 | -217.0 |
| DEFB123 | -222.0 |
| APOB | -225.0 |
| MUC4 | -229.0 |
| NCF4 | -238.0 |
| C4A | -284.5 |
| C4B | -284.5 |
| VTN | -348.0 |
| DYNLT1 | -362.0 |
| NOS2 | -416.0 |
| UBE2M | -450.0 |
| DHX58 | -480.0 |
| NOD1 | -481.0 |
| PLEKHO2 | -482.0 |
| MEFV | -509.0 |
| MGST1 | -510.0 |
| CFB | -557.0 |
| PSTPIP1 | -629.0 |
| YES1 | -652.0 |
| FPR2 | -668.0 |
| MEF2A | -686.0 |
| RAB7A | -729.0 |
| ADAM10 | -747.0 |
| GAA | -795.0 |
| MUC21 | -851.0 |
| C5AR1 | -852.0 |
| MAPK1 | -857.0 |
| ATP11B | -863.0 |
| PSMD14 | -865.0 |
| ATG5 | -924.0 |
| HTN3 | -934.0 |
| LAMTOR3 | -947.0 |
| PSMD6 | -961.0 |
| FBXW11 | -964.0 |
| POLR2L | -971.0 |
| TANK | -981.0 |
| PLD1 | -986.0 |
| BRK1 | -989.0 |
| ATP6V0A4 | -998.0 |
| NOS3 | -1025.0 |
| BAIAP2 | -1045.0 |
| RAP1A | -1052.0 |
| NFKB2 | -1089.0 |
| QPCT | -1100.0 |
| BPIFA1 | -1112.0 |
| DEFB132 | -1117.0 |
| MMP9 | -1149.0 |
| ZBP1 | -1155.0 |
| MVP | -1169.0 |
| CD209 | -1191.0 |
| PPIA | -1195.0 |
| PRKDC | -1203.0 |
| CTNNB1 | -1232.0 |
| MAP3K1 | -1248.0 |
| ARHGAP9 | -1263.0 |
| NRAS | -1287.0 |
| PSMB7 | -1294.0 |
| ALPK1 | -1313.0 |
| SELL | -1341.0 |
| MAPK7 | -1357.0 |
| FUCA1 | -1368.0 |
| CDC34 | -1369.0 |
| TSPAN14 | -1391.0 |
| AHCYL1 | -1419.0 |
| CPNE1 | -1432.0 |
| ITGAV | -1444.0 |
| PADI2 | -1463.0 |
| PRKCQ | -1471.0 |
| DNM3 | -1481.0 |
| CST3 | -1488.0 |
| CAT | -1504.0 |
| C6 | -1505.0 |
| ACLY | -1513.0 |
| LPO | -1523.0 |
| NFASC | -1525.0 |
| RASGRP1 | -1541.0 |
| PLAU | -1561.0 |
| HBB | -1563.0 |
| NOD2 | -1614.0 |
| CALM1 | -1622.0 |
| DOCK1 | -1627.0 |
| HRAS | -1663.0 |
| NIT2 | -1664.0 |
| APRT | -1707.0 |
| DERA | -1708.0 |
| CYLD | -1716.0 |
| MAP3K7 | -1717.0 |
| CD44 | -1755.0 |
| RPS6KA5 | -1764.0 |
| GNS | -1767.0 |
| CASP2 | -1770.0 |
| ACTR2 | -1776.0 |
| RIPK2 | -1779.0 |
| NLRX1 | -1784.0 |
| DNM2 | -1901.0 |
| ADGRE5 | -1904.0 |
| GALNS | -1909.0 |
| PANX1 | -1942.0 |
| ITK | -1957.0 |
| DNAJC5 | -1965.0 |
| MAP2K4 | -2008.0 |
| TRAF3 | -2012.0 |
| ATP6V1H | -2022.0 |
| MAP2K6 | -2038.0 |
| GYG1 | -2075.0 |
| ATG7 | -2089.0 |
| PPP2R1A | -2107.0 |
| CEP290 | -2146.0 |
| C8A | -2230.0 |
| MAPK11 | -2236.0 |
| TUBB | -2261.0 |
| PSMB10 | -2290.0 |
| ATOX1 | -2291.0 |
| KRT1 | -2294.0 |
| FCER1G | -2318.0 |
| EP300 | -2354.0 |
| AGL | -2360.0 |
| CYFIP2 | -2379.0 |
| PSMB6 | -2408.0 |
| CREBBP | -2409.0 |
| CUL1 | -2437.0 |
| POLR3E | -2463.0 |
| CD58 | -2473.0 |
| RAC1 | -2500.0 |
| RAP1B | -2541.0 |
| PSMD9 | -2570.0 |
| ELANE | -2592.0 |
| CMTM6 | -2626.0 |
| TNFAIP6 | -2628.0 |
| ATP6V0D1 | -2636.0 |
| CASP4 | -2640.0 |
| N4BP1 | -2646.0 |
| USP18 | -2665.0 |
| MUC17 | -2676.0 |
| TLR5 | -2722.0 |
| CD300E | -2733.0 |
| ATP6V1C2 | -2734.0 |
| RNASET2 | -2760.0 |
| NOS1 | -2769.0 |
| DOCK2 | -2783.0 |
| RPS6KA2 | -2842.0 |
| SUGT1 | -2843.0 |
| EEF1A1 | -2905.0 |
| NDUFC2 | -2916.0 |
| CLEC4D | -2936.0 |
| PDAP1 | -3014.0 |
| TRIM56 | -3031.0 |
| HVCN1 | -3090.0 |
| C6orf120 | -3115.0 |
| C1R | -3122.0 |
| C7 | -3232.0 |
| TRPM2 | -3235.0 |
| ATP11A | -3239.0 |
| FOLR3 | -3252.0 |
| RIGI | -3256.0 |
| MAPK10 | -3279.0 |
| HLA-B | -3298.0 |
| FRK | -3327.0 |
| PTAFR | -3334.0 |
| MLEC | -3335.0 |
| ICAM2 | -3381.0 |
| PPP3CA | -3394.0 |
| AP2A2 | -3410.0 |
| ELMO2 | -3411.0 |
| CR1 | -3419.0 |
| C1S | -3422.0 |
| EPX | -3442.0 |
| STOM | -3459.0 |
| TREX1 | -3471.0 |
| TLR10 | -3499.0 |
| DEFB1 | -3518.0 |
| DYNLL1 | -3541.0 |
| IFNB1 | -3599.0 |
| POLR3C | -3602.0 |
| PIK3R4 | -3618.0 |
| CCL17 | -3629.0 |
| PTPRN2 | -3638.0 |
| MYO10 | -3654.0 |
| ACP3 | -3656.0 |
| VAMP8 | -3745.0 |
| LTF | -3752.0 |
| UBA52 | -3755.0 |
| CD46 | -3785.0 |
| PRKCE | -3802.0 |
| ATP8B4 | -3807.0 |
| DEGS1 | -3808.0 |
| BIRC3 | -3823.0 |
| ALOX5 | -3865.0 |
| MPO | -3889.0 |
| ACAA1 | -3917.0 |
| DIAPH1 | -3925.0 |
| CYSTM1 | -3941.0 |
| ARHGAP45 | -3978.0 |
| ACTR1B | -4000.0 |
| PKP1 | -4060.0 |
| APAF1 | -4071.0 |
| SERPING1 | -4110.0 |
| SRC | -4161.0 |
| VAPA | -4193.0 |
| LEAP2 | -4207.0 |
| PDPK1 | -4211.0 |
| CRP | -4241.0 |
| ITLN1 | -4264.0 |
| CLEC4E | -4300.0 |
| QSOX1 | -4328.0 |
| DEFB116 | -4377.0 |
| PELI1 | -4405.0 |
| WASL | -4439.0 |
| FAF2 | -4450.0 |
| PLCG2 | -4486.0 |
| CPN1 | -4516.0 |
| CARD11 | -4528.0 |
| SIRPB1 | -4530.0 |
| ITPR1 | -4562.0 |
| SIGLEC5 | -4589.0 |
| ATF1 | -4593.0 |
| NBEAL2 | -4595.0 |
| CHRNB4 | -4597.0 |
| TMEM30A | -4618.0 |
| CRISPLD2 | -4630.0 |
| CD33 | -4634.0 |
| PSMB5 | -4687.0 |
| TRIM32 | -4743.0 |
| POLR2F | -4762.0 |
| FUCA2 | -4775.0 |
| VAV2 | -4801.0 |
| TXK | -4825.0 |
| DEFB104A | -4840.5 |
| DEFB104B | -4840.5 |
| PLA2G2A | -4869.0 |
| NLRP4 | -4880.0 |
| PAK1 | -4897.0 |
| ATG12 | -4898.0 |
| ITGAX | -4914.0 |
| TTR | -4959.0 |
| ABI2 | -4983.0 |
| BPIFA2 | -4993.0 |
| PELI2 | -5066.0 |
| HMOX1 | -5069.0 |
| STK11IP | -5075.0 |
| NLRC3 | -5104.0 |
| PTPRC | -5153.0 |
| RASGRP2 | -5163.0 |
| DEFB113 | -5170.0 |
| PRKCSH | -5186.0 |
| NFATC1 | -5197.0 |
| PSMD7 | -5198.0 |
| MUCL1 | -5204.0 |
| FCGR3A | -5243.0 |
| RHOA | -5289.0 |
| PSMD4 | -5337.0 |
| GLB1 | -5373.0 |
| S100A9 | -5377.0 |
| UBE2D1 | -5394.0 |
| PRKCD | -5412.0 |
| FPR1 | -5421.0 |
| MAPK3 | -5444.0 |
| PLPP5 | -5504.0 |
| DSG1 | -5553.0 |
| CDK13 | -5608.0 |
| ABCA13 | -5622.0 |
| MGAM | -5676.0 |
| ANXA2 | -5678.0 |
| BST2 | -5683.0 |
| HLA-C | -5724.0 |
| SCAMP1 | -5735.0 |
| LGALS3 | -5792.0 |
| HSPA1B | -5824.0 |
| TAB2 | -5833.0 |
| PSMB1 | -5858.0 |
| CYB5R3 | -5860.0 |
| PLA2G6 | -5873.0 |
| ATP6V0B | -5878.0 |
| CD47 | -5894.0 |
| COLEC10 | -5899.0 |
| SARM1 | -5913.0 |
| CALML5 | -5985.0 |
| VPS35L | -6012.0 |
| DEFB133 | -6018.0 |
| BST1 | -6053.0 |
| LCN2 | -6073.0 |
| DYNC1H1 | -6092.0 |
| LAMP1 | -6153.0 |
| CD247 | -6156.0 |
| DDX41 | -6179.0 |
| TRAF6 | -6221.0 |
| ORM1 | -6249.0 |
| POLR2H | -6261.0 |
| GSDME | -6277.0 |
| FCGR3B | -6313.0 |
| NFATC2 | -6326.0 |
| PGAM1 | -6368.0 |
| IL1B | -6400.0 |
| ADGRG3 | -6433.0 |
| ARPC1A | -6449.0 |
| PTGES2 | -6502.0 |
| PIK3C3 | -6505.0 |
| HSPA1A | -6507.0 |
| PPIE | -6522.0 |
| RIPK1 | -6646.0 |
| UBE2L6 | -6675.0 |
| USP14 | -6682.0 |
| CLEC10A | -6696.0 |
| TXNDC5 | -6718.0 |
| DTX4 | -6731.0 |
| SPTAN1 | -6744.0 |
| RIPK3 | -6774.0 |
| MUC15 | -6809.0 |
| S100A1 | -6851.0 |
| MUC7 | -6962.0 |
| TRIM4 | -6985.0 |
| C8G | -7001.0 |
| VCP | -7056.0 |
| SIGLEC14 | -7085.0 |
| OSTF1 | -7119.0 |
| CRACR2A | -7148.0 |
| DNAJC13 | -7176.0 |
| PPP2CB | -7216.0 |
| RAB44 | -7228.0 |
| UBR4 | -7235.0 |
| NME2 | -7263.0 |
| NLRP1 | -7268.0 |
| NFKB1 | -7273.0 |
| PPP3CB | -7407.0 |
| DHX36 | -7426.0 |
| CCR6 | -7453.0 |
| TKFC | -7546.0 |
| GSDMD | -7575.0 |
| WASF3 | -7580.0 |
| CRK | -7608.0 |
| FGG | -7630.0 |
| CNN2 | -7683.0 |
| ITPR3 | -7685.0 |
| GPR84 | -7694.0 |
| PSMD8 | -7723.0 |
| CFHR5 | -7744.0 |
| BIRC2 | -7754.0 |
| PLCG1 | -7786.0 |
| CFH | -7890.0 |
| NCKAP1 | -7930.0 |
| PYGB | -7961.0 |
| RELA | -8093.0 |
| NLRC4 | -8113.0 |
| TRAF2 | -8123.0 |
| CYFIP1 | -8125.0 |
| CTSB | -8139.0 |
| CPN2 | -8178.0 |
| SLC27A2 | -8217.0 |
| PPP2R1B | -8245.0 |
| PTPN4 | -8273.0 |
| CRISP3 | -8274.0 |
| ABL1 | -8289.0 |
| FCGR2A | -8299.0 |
| NCSTN | -8401.0 |
| CSTB | -8435.0 |
| C8B | -8437.0 |
| PLPP4 | -8472.0 |
| NCKIPSD | -8499.0 |
| PDXK | -8520.0 |
| ATP6V1G3 | -8586.0 |
| MAPK8 | -8692.0 |
| REG3G | -8735.0 |
| CFHR4 | -8761.0 |
| CTSH | -8771.0 |
| SERPINA3 | -8775.0 |
| DHX9 | -8784.0 |
| OLFM4 | -8790.0 |
| CTSL | -8793.0 |
| FLG2 | -8798.0 |
| COMMD9 | -8814.0 |
| HLA-A | -8825.0 |
| PIGR | -8858.0 |
| JUP | -8895.0 |
| MYH2 | -8973.0 |
| KLRK1 | -8978.0 |
| SAA1 | -8998.0 |
| COLEC11 | -9085.0 |
| AOC1 | -9087.0 |
| C1QB | -9131.0 |
| CAMP | -9139.0 |
| LRRC7 | -9142.0 |
| MUC5B | -9198.0 |
| CASP1 | -9200.0 |
| CANT1 | -9242.0 |
| WIPF3 | -9290.0 |
| C9 | -9338.0 |
| CTSS | -9356.0 |
| C1QA | -9380.0 |
| PTPRB | -9398.0 |
| IRF7 | -9417.0 |
| TARM1 | -9418.0 |
| BPIFB4 | -9442.0 |
| CCL22 | -9480.0 |
| PSMD5 | -9524.0 |
| DEFA6 | -9549.0 |
| CD4 | -9562.0 |
| LYZ | -9592.0 |
| GNLY | -9631.0 |
| S100A7A | -9637.0 |
| HSPA6 | -9683.0 |
| CEACAM3 | -9715.0 |
| HTN1 | -9811.0 |
| MUC13 | -9812.0 |
| AIM2 | -9837.0 |
| IFNA6 | -9855.0 |
| PECAM1 | -9913.0 |
| DEFA4 | -9918.0 |
| DEFB135 | -9947.0 |
| CFHR2 | -10033.0 |
| S100A7 | -10070.0 |
| MMP8 | -10091.0 |
| SERPINA1 | -10139.0 |
| BPIFB2 | -10151.0 |
| CHI3L1 | -10177.0 |
| FCN1 | -10189.0 |
| SFTPA2 | -10194.0 |
| DEFB128 | -10199.0 |
| ART1 | -10204.0 |
| RETN | -10246.0 |
| MUC5AC | -10327.0 |
| FGA | -10390.0 |
| S100A12 | -10430.0 |
| CFI | -10441.0 |
| IFNA5 | -10479.0 |
| DEFB110 | -10550.0 |
| DEFB124 | -10562.0 |
| TREM2 | -10578.0 |
| ARG1 | -10584.0 |
| HRNR | -10592.0 |
| ORM2 | -10718.0 |
| RNASE8 | -10721.0 |
| AZU1 | -10756.0 |
| MBL2 | -10811.0 |
| IFNA21 | -10852.0 |
REACTOME_NONSENSE_MEDIATED_DECAY_NMD
| 1443 | |
|---|---|
| set | REACTOME_NONSENSE_MEDIATED_DECAY_NMD |
| setSize | 107 |
| pANOVA | 8.57e-06 |
| s.dist | 0.249 |
| p.adjustANOVA | 0.000612 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL14 | 10215.0 |
| RPL18 | 10082.0 |
| RPL10A | 10035.0 |
| RPL23A | 9830.0 |
| RPS13 | 9737.0 |
| RBM8A | 9578.0 |
| RPL38 | 9474.0 |
| RPS21 | 9255.0 |
| RPLP0 | 9213.0 |
| RPL29 | 9165.0 |
| RPS3A | 8946.0 |
| RPL28 | 8875.0 |
| PABPC1 | 8543.0 |
| RPL36AL | 8459.5 |
| RPL22L1 | 8449.0 |
| RPL31 | 8273.0 |
| RPS24 | 8170.0 |
| RPS23 | 8094.0 |
| RPL26 | 8016.0 |
| RPS20 | 7907.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL14 | 10215.0 |
| RPL18 | 10082.0 |
| RPL10A | 10035.0 |
| RPL23A | 9830.0 |
| RPS13 | 9737.0 |
| RBM8A | 9578.0 |
| RPL38 | 9474.0 |
| RPS21 | 9255.0 |
| RPLP0 | 9213.0 |
| RPL29 | 9165.0 |
| RPS3A | 8946.0 |
| RPL28 | 8875.0 |
| PABPC1 | 8543.0 |
| RPL36AL | 8459.5 |
| RPL22L1 | 8449.0 |
| RPL31 | 8273.0 |
| RPS24 | 8170.0 |
| RPS23 | 8094.0 |
| RPL26 | 8016.0 |
| RPS20 | 7907.0 |
| UPF2 | 7759.0 |
| RPS29 | 7621.0 |
| RPL34 | 7423.0 |
| RPS19 | 7419.0 |
| RPS3 | 7411.0 |
| RPL41 | 7335.0 |
| RPL6 | 7304.0 |
| RPS27A | 7120.0 |
| RPL23 | 6935.0 |
| FAU | 6424.0 |
| EIF4A3 | 6420.0 |
| RPL11 | 6414.0 |
| RPL21 | 6341.0 |
| RPL13 | 6125.0 |
| RPS26 | 6058.0 |
| RPL7A | 5991.0 |
| RPS16 | 5896.0 |
| RPL8 | 5822.0 |
| RPS7 | 5716.0 |
| NCBP1 | 5705.0 |
| RPL26L1 | 5531.0 |
| RPS8 | 5431.0 |
| RPL37A | 5292.0 |
| RPL3L | 5206.0 |
| RPL13A | 5131.5 |
| SMG5 | 5060.0 |
| RPS10 | 5058.0 |
| SMG7 | 5028.0 |
| RPL19 | 4913.0 |
| RPS18 | 4856.0 |
| RPL9 | 4760.0 |
| RPS27 | 4711.0 |
| RNPS1 | 4528.0 |
| RPS12 | 4501.0 |
| RPL35 | 4434.0 |
| UPF1 | 4279.0 |
| RPL35A | 4218.0 |
| RPL17 | 4202.0 |
| CASC3 | 4044.0 |
| SMG1 | 3772.0 |
| RPSA | 3281.0 |
| RPL3 | 3240.0 |
| RPL12 | 2822.0 |
| RPS28 | 2669.0 |
| RPL27A | 2494.0 |
| RPL15 | 2382.0 |
| RPL32 | 2362.0 |
| PPP2CA | 2292.0 |
| RPS15A | 2095.0 |
| RPS25 | 1988.0 |
| RPLP1 | 1762.0 |
| EIF4G1 | 1551.0 |
| RPL7 | 1442.0 |
| PNRC2 | 1090.0 |
| PPP2R2A | 1071.0 |
| SMG9 | 1036.0 |
| RPL5 | -139.0 |
| SMG8 | -579.0 |
| RPS2 | -1028.0 |
| RPS14 | -1691.0 |
| MAGOHB | -1800.0 |
| RPL30 | -2061.0 |
| PPP2R1A | -2107.0 |
| GSPT1 | -2497.0 |
| ETF1 | -2575.0 |
| RPS5 | -2579.0 |
| RPS6 | -2673.0 |
| RPL39L | -3132.0 |
| NCBP2 | -3139.0 |
| RPL37 | -3282.0 |
| UBA52 | -3755.0 |
| SMG6 | -4132.0 |
| RPS15 | -4150.0 |
| RPL24 | -4644.0 |
| RPS9 | -4650.0 |
| RPL4 | -5128.0 |
| RPL27 | -5306.0 |
| RPL18A | -5425.0 |
| RPL22 | -5765.0 |
| RPLP2 | -5777.0 |
| RPS27L | -5945.0 |
| DCP1A | -7071.0 |
| UPF3A | -7770.0 |
| RPL36 | -8155.0 |
| RPS11 | -8626.0 |
| MAGOH | -9309.0 |
| RPL10L | -10090.0 |
REACTOME_DNA_REPLICATION
| 1113 | |
|---|---|
| set | REACTOME_DNA_REPLICATION |
| setSize | 178 |
| pANOVA | 9.15e-06 |
| s.dist | 0.193 |
| p.adjustANOVA | 0.000626 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| H4C8 | 10752 |
| POLE3 | 10464 |
| POLD4 | 10382 |
| PSMD12 | 10325 |
| PSMC6 | 9977 |
| H2AJ | 9870 |
| PSMB3 | 9858 |
| UBC | 9476 |
| MCM2 | 9367 |
| RBX1 | 9293 |
| MCM10 | 9189 |
| H3C10 | 9015 |
| FEN1 | 9002 |
| GINS2 | 8991 |
| H3C11 | 8963 |
| H4C12 | 8883 |
| H4C2 | 8690 |
| KPNA6 | 8687 |
| PSME2 | 8685 |
| H3-3A | 8639 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| H4C8 | 10752.0 |
| POLE3 | 10464.0 |
| POLD4 | 10382.0 |
| PSMD12 | 10325.0 |
| PSMC6 | 9977.0 |
| H2AJ | 9870.0 |
| PSMB3 | 9858.0 |
| UBC | 9476.0 |
| MCM2 | 9367.0 |
| RBX1 | 9293.0 |
| MCM10 | 9189.0 |
| H3C10 | 9015.0 |
| FEN1 | 9002.0 |
| GINS2 | 8991.0 |
| H3C11 | 8963.0 |
| H4C12 | 8883.0 |
| H4C2 | 8690.0 |
| KPNA6 | 8687.0 |
| PSME2 | 8685.0 |
| H3-3A | 8639.0 |
| H2BC13 | 8609.0 |
| H2BC1 | 8383.0 |
| DNA2 | 8298.0 |
| PSMB4 | 8180.0 |
| H3C12 | 8052.0 |
| CDC45 | 7992.0 |
| PSMD13 | 7901.0 |
| H2AZ2 | 7814.0 |
| H2AC7 | 7754.5 |
| H2BC7 | 7754.5 |
| PSME4 | 7705.0 |
| UBB | 7674.0 |
| PSMB2 | 7641.0 |
| POLD1 | 7462.0 |
| PSMB11 | 7359.0 |
| H4C16 | 7260.0 |
| PSMA6 | 7190.0 |
| RPS27A | 7120.0 |
| PSMA1 | 7018.0 |
| ANAPC11 | 6955.0 |
| CDK2 | 6939.0 |
| ORC1 | 6803.0 |
| PSMD3 | 6672.0 |
| H2AC8 | 6630.0 |
| MCM5 | 6536.0 |
| H3-3B | 6110.0 |
| H2BC8 | 6087.0 |
| H4C3 | 5935.0 |
| ANAPC10 | 5865.0 |
| H4C1 | 5864.0 |
| PSMC1 | 5715.0 |
| MCM4 | 5708.0 |
| RPA1 | 5651.0 |
| PSMD2 | 5624.0 |
| H3C1 | 5598.0 |
| PSMA5 | 5362.0 |
| ANAPC2 | 5346.0 |
| DBF4 | 5250.0 |
| PSMA4 | 5246.0 |
| PSMC5 | 5193.0 |
| H2BC5 | 5130.0 |
| H4C6 | 4952.0 |
| MCM3 | 4832.0 |
| PCNA | 4821.0 |
| H3C4 | 4718.0 |
| ANAPC5 | 4671.0 |
| GINS1 | 4665.0 |
| H2BC3 | 4658.0 |
| H4C13 | 4630.0 |
| ORC2 | 4592.0 |
| H4C11 | 4553.0 |
| KPNB1 | 4376.0 |
| PSMF1 | 4311.0 |
| CDT1 | 4263.0 |
| PSMD1 | 4227.0 |
| PSME3 | 4172.0 |
| PSMC2 | 4088.0 |
| H2BC10 | 3947.0 |
| PSMA8 | 3923.0 |
| PSMA7 | 3903.0 |
| PSME1 | 3866.0 |
| PSMA3 | 3850.0 |
| H4C4 | 3785.0 |
| CCNA1 | 3593.0 |
| SKP1 | 3534.0 |
| PSMB9 | 3459.0 |
| KPNA1 | 3308.0 |
| H2BC17 | 3276.0 |
| CCNE2 | 3190.0 |
| RFC2 | 3136.0 |
| POLE4 | 3064.0 |
| CDC27 | 3049.0 |
| H3C6 | 3009.0 |
| PSMC4 | 3004.0 |
| PSMC3 | 2960.0 |
| H2AC6 | 2946.0 |
| PRIM1 | 2888.0 |
| MCM7 | 2717.0 |
| H3C8 | 2699.0 |
| SEM1 | 2517.0 |
| H2AC4 | 2379.0 |
| CDC26 | 2306.0 |
| MCM8 | 2177.0 |
| ORC4 | 1976.0 |
| ANAPC15 | 1950.0 |
| CDC23 | 1927.0 |
| CDC7 | 1479.0 |
| H3C2 | 1438.0 |
| H2BC11 | 1338.0 |
| RPA2 | 1117.0 |
| RFC4 | 824.0 |
| CDC16 | 754.0 |
| PSMD11 | 620.0 |
| H2AX | 499.0 |
| PSMB8 | 447.0 |
| POLD2 | 347.0 |
| H2BC15 | 240.0 |
| POLE2 | 60.0 |
| ORC3 | 36.0 |
| FZR1 | 16.0 |
| MCM6 | 2.0 |
| POLA2 | -22.0 |
| RFC5 | -81.0 |
| PSMA2 | -85.0 |
| ANAPC4 | -310.0 |
| H2AZ1 | -360.0 |
| H3C3 | -546.0 |
| ORC5 | -617.0 |
| H2AC20 | -674.0 |
| GMNN | -730.0 |
| PSMD14 | -865.0 |
| GINS4 | -959.0 |
| PSMD6 | -961.0 |
| ANAPC1 | -1043.0 |
| PSMB7 | -1294.0 |
| UBE2S | -1361.0 |
| H2BC6 | -1396.0 |
| LIG1 | -1478.0 |
| H2BC4 | -2094.0 |
| H2BC12 | -2115.0 |
| PSMB10 | -2290.0 |
| PSMB6 | -2408.0 |
| CUL1 | -2437.0 |
| UBE2C | -2539.0 |
| PSMD9 | -2570.0 |
| UBE2E1 | -2647.0 |
| ORC6 | -3467.0 |
| CCNA2 | -3495.0 |
| UBA52 | -3755.0 |
| ANAPC7 | -3780.0 |
| RFC1 | -3990.0 |
| ANAPC16 | -4502.0 |
| PSMB5 | -4687.0 |
| SKP2 | -4745.0 |
| H2BC9 | -4907.5 |
| H3C7 | -4907.5 |
| H4C5 | -4941.0 |
| RFC3 | -4967.0 |
| PSMD7 | -5198.0 |
| PSMD4 | -5337.0 |
| UBE2D1 | -5394.0 |
| POLD3 | -5419.0 |
| H2BC21 | -5773.0 |
| PSMB1 | -5858.0 |
| PRIM2 | -6159.0 |
| H2BC26 | -6695.0 |
| CDC6 | -7443.0 |
| PSMD8 | -7723.0 |
| GINS3 | -7990.0 |
| RPA3 | -8086.0 |
| POLE | -8297.0 |
| H2AC14 | -8606.0 |
| H2BC14 | -8730.0 |
| H4C9 | -9282.0 |
| PSMD5 | -9524.0 |
| CCNE1 | -9930.0 |
| H2AC18 | -10224.5 |
| H2AC19 | -10224.5 |
REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_HSCS
| 1282 | |
|---|---|
| set | REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_HSCS |
| setSize | 121 |
| pANOVA | 1.28e-05 |
| s.dist | 0.23 |
| p.adjustANOVA | 0.000804 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| H4C8 | 10752 |
| PSMD12 | 10325 |
| PSMC6 | 9977 |
| H2AJ | 9870 |
| PSMB3 | 9858 |
| GATA2 | 9817 |
| CBFB | 9784 |
| UBC | 9476 |
| H3C10 | 9015 |
| H3C11 | 8963 |
| H4C12 | 8883 |
| LDB1 | 8879 |
| H4C2 | 8690 |
| PSME2 | 8685 |
| H3-3A | 8639 |
| H2BC13 | 8609 |
| CCNH | 8435 |
| LMO2 | 8413 |
| H2BC1 | 8383 |
| SPI1 | 8199 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| H4C8 | 10752.0 |
| PSMD12 | 10325.0 |
| PSMC6 | 9977.0 |
| H2AJ | 9870.0 |
| PSMB3 | 9858.0 |
| GATA2 | 9817.0 |
| CBFB | 9784.0 |
| UBC | 9476.0 |
| H3C10 | 9015.0 |
| H3C11 | 8963.0 |
| H4C12 | 8883.0 |
| LDB1 | 8879.0 |
| H4C2 | 8690.0 |
| PSME2 | 8685.0 |
| H3-3A | 8639.0 |
| H2BC13 | 8609.0 |
| CCNH | 8435.0 |
| LMO2 | 8413.0 |
| H2BC1 | 8383.0 |
| SPI1 | 8199.0 |
| PSMB4 | 8180.0 |
| H3C12 | 8052.0 |
| PSMD13 | 7901.0 |
| H2AZ2 | 7814.0 |
| H2AC7 | 7754.5 |
| H2BC7 | 7754.5 |
| PSME4 | 7705.0 |
| UBB | 7674.0 |
| PSMB2 | 7641.0 |
| PSMB11 | 7359.0 |
| H4C16 | 7260.0 |
| PSMA6 | 7190.0 |
| RPS27A | 7120.0 |
| PSMA1 | 7018.0 |
| PSMD3 | 6672.0 |
| H2AC8 | 6630.0 |
| H3-3B | 6110.0 |
| H2BC8 | 6087.0 |
| H4C3 | 5935.0 |
| H4C1 | 5864.0 |
| PSMC1 | 5715.0 |
| PSMD2 | 5624.0 |
| H3C1 | 5598.0 |
| PSMA5 | 5362.0 |
| PSMA4 | 5246.0 |
| PSMC5 | 5193.0 |
| LMO1 | 5192.0 |
| H2BC5 | 5130.0 |
| KMT2A | 5079.0 |
| TP73 | 5000.0 |
| H4C6 | 4952.0 |
| H3C4 | 4718.0 |
| H2BC3 | 4658.0 |
| H4C13 | 4630.0 |
| H4C11 | 4553.0 |
| PSMF1 | 4311.0 |
| PSMD1 | 4227.0 |
| PSME3 | 4172.0 |
| GATA3 | 4111.0 |
| PSMC2 | 4088.0 |
| H2BC10 | 3947.0 |
| PSMA8 | 3923.0 |
| TAL1 | 3910.0 |
| PSMA7 | 3903.0 |
| PSME1 | 3866.0 |
| PSMA3 | 3850.0 |
| H4C4 | 3785.0 |
| PSMB9 | 3459.0 |
| H2BC17 | 3276.0 |
| MYB | 3241.0 |
| H3C6 | 3009.0 |
| PSMC4 | 3004.0 |
| PSMC3 | 2960.0 |
| H2AC6 | 2946.0 |
| H3C8 | 2699.0 |
| SEM1 | 2517.0 |
| H2AC4 | 2379.0 |
| ITCH | 2310.0 |
| H3C2 | 1438.0 |
| H2BC11 | 1338.0 |
| PSMD11 | 620.0 |
| H2AX | 499.0 |
| PSMB8 | 447.0 |
| H2BC15 | 240.0 |
| PSMA2 | -85.0 |
| H2AZ1 | -360.0 |
| H3C3 | -546.0 |
| H2AC20 | -674.0 |
| MNAT1 | -717.0 |
| PSMD14 | -865.0 |
| PSMD6 | -961.0 |
| PSMB7 | -1294.0 |
| H2BC6 | -1396.0 |
| TCF3 | -1910.0 |
| H2BC4 | -2094.0 |
| H2BC12 | -2115.0 |
| PSMB10 | -2290.0 |
| PSMB6 | -2408.0 |
| PSMD9 | -2570.0 |
| UBA52 | -3755.0 |
| TCF12 | -3867.0 |
| PSMB5 | -4687.0 |
| H2BC9 | -4907.5 |
| H3C7 | -4907.5 |
| CDK7 | -4917.0 |
| H4C5 | -4941.0 |
| PSMD7 | -5198.0 |
| PSMD4 | -5337.0 |
| YAP1 | -5356.0 |
| H2BC21 | -5773.0 |
| PSMB1 | -5858.0 |
| H2BC26 | -6695.0 |
| PSMD8 | -7723.0 |
| RUNX1 | -7923.0 |
| ABL1 | -8289.0 |
| H2AC14 | -8606.0 |
| H2BC14 | -8730.0 |
| H4C9 | -9282.0 |
| PSMD5 | -9524.0 |
| H2AC18 | -10224.5 |
| H2AC19 | -10224.5 |
REACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS
| 1476 | |
|---|---|
| set | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS |
| setSize | 83 |
| pANOVA | 1.3e-05 |
| s.dist | 0.277 |
| p.adjustANOVA | 0.000804 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| E2F1 | 10764 |
| H4C8 | 10752 |
| CDK4 | 10506 |
| CEBPE | 10303 |
| CEBPA | 10126 |
| H2AJ | 9870 |
| GATA2 | 9817 |
| CBFB | 9784 |
| STAT3 | 9471 |
| DEK | 9433 |
| H3C10 | 9015 |
| RARA | 9010 |
| H3C11 | 8963 |
| H4C12 | 8883 |
| H4C2 | 8690 |
| H3-3A | 8639 |
| H2BC13 | 8609 |
| H2BC1 | 8383 |
| SPI1 | 8199 |
| GFI1 | 8157 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| E2F1 | 10764.0 |
| H4C8 | 10752.0 |
| CDK4 | 10506.0 |
| CEBPE | 10303.0 |
| CEBPA | 10126.0 |
| H2AJ | 9870.0 |
| GATA2 | 9817.0 |
| CBFB | 9784.0 |
| STAT3 | 9471.0 |
| DEK | 9433.0 |
| H3C10 | 9015.0 |
| RARA | 9010.0 |
| H3C11 | 8963.0 |
| H4C12 | 8883.0 |
| H4C2 | 8690.0 |
| H3-3A | 8639.0 |
| H2BC13 | 8609.0 |
| H2BC1 | 8383.0 |
| SPI1 | 8199.0 |
| GFI1 | 8157.0 |
| H3C12 | 8052.0 |
| H2AZ2 | 7814.0 |
| H2AC7 | 7754.5 |
| H2BC7 | 7754.5 |
| H4C16 | 7260.0 |
| CDK2 | 6939.0 |
| H2AC8 | 6630.0 |
| H3-3B | 6110.0 |
| H2BC8 | 6087.0 |
| CREB1 | 6047.0 |
| H4C3 | 5935.0 |
| H4C1 | 5864.0 |
| H3C1 | 5598.0 |
| H2BC5 | 5130.0 |
| KMT2A | 5079.0 |
| CDKN1A | 5054.0 |
| H4C6 | 4952.0 |
| H3C4 | 4718.0 |
| CEBPB | 4682.0 |
| H2BC3 | 4658.0 |
| H4C13 | 4630.0 |
| H4C11 | 4553.0 |
| H2BC10 | 3947.0 |
| TAL1 | 3910.0 |
| H4C4 | 3785.0 |
| CSF3R | 3484.0 |
| TFDP2 | 3339.0 |
| FLI1 | 3313.0 |
| H2BC17 | 3276.0 |
| MYB | 3241.0 |
| H3C6 | 3009.0 |
| H2AC6 | 2946.0 |
| H3C8 | 2699.0 |
| H2AC4 | 2379.0 |
| H3C2 | 1438.0 |
| H2BC11 | 1338.0 |
| PML | 1014.0 |
| H2AX | 499.0 |
| IL6R | 467.0 |
| H2BC15 | 240.0 |
| H2AZ1 | -360.0 |
| H3C3 | -546.0 |
| LEF1 | -661.0 |
| H2AC20 | -674.0 |
| KLF5 | -803.0 |
| RXRA | -1218.0 |
| H2BC6 | -1396.0 |
| H2BC4 | -2094.0 |
| H2BC12 | -2115.0 |
| TFDP1 | -2156.0 |
| EP300 | -2354.0 |
| MYC | -2593.0 |
| H2BC9 | -4907.5 |
| H3C7 | -4907.5 |
| H4C5 | -4941.0 |
| H2BC21 | -5773.0 |
| H2BC26 | -6695.0 |
| RUNX1 | -7923.0 |
| H2AC14 | -8606.0 |
| H2BC14 | -8730.0 |
| H4C9 | -9282.0 |
| H2AC18 | -10224.5 |
| H2AC19 | -10224.5 |
REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE
| 500 | |
|---|---|
| set | REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE |
| setSize | 228 |
| pANOVA | 1.32e-05 |
| s.dist | 0.167 |
| p.adjustANOVA | 0.000804 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CHMP4C | 10392 |
| CENPQ | 10378 |
| PSMD12 | 10325 |
| DYNC1LI2 | 10216 |
| BANF1 | 10027 |
| PSMC6 | 9977 |
| ESPL1 | 9956 |
| KNTC1 | 9932 |
| PSMB3 | 9858 |
| UBC | 9476 |
| DSN1 | 9391 |
| TUBB6 | 9058 |
| PPP2R5B | 9055 |
| POM121 | 8943 |
| ZWINT | 8928 |
| LEMD3 | 8915 |
| BUB1B | 8870 |
| AURKB | 8795 |
| PPP2R5D | 8711 |
| ITGB3BP | 8707 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CHMP4C | 10392 |
| CENPQ | 10378 |
| PSMD12 | 10325 |
| DYNC1LI2 | 10216 |
| BANF1 | 10027 |
| PSMC6 | 9977 |
| ESPL1 | 9956 |
| KNTC1 | 9932 |
| PSMB3 | 9858 |
| UBC | 9476 |
| DSN1 | 9391 |
| TUBB6 | 9058 |
| PPP2R5B | 9055 |
| POM121 | 8943 |
| ZWINT | 8928 |
| LEMD3 | 8915 |
| BUB1B | 8870 |
| AURKB | 8795 |
| PPP2R5D | 8711 |
| ITGB3BP | 8707 |
| PSME2 | 8685 |
| CLIP1 | 8357 |
| TUBAL3 | 8355 |
| DYNLL2 | 8325 |
| SIRT2 | 8280 |
| PSMB4 | 8180 |
| TUBB4B | 7956 |
| PSMD13 | 7901 |
| TUBB3 | 7767 |
| NUP155 | 7761 |
| CENPM | 7709 |
| PSME4 | 7705 |
| CENPL | 7683 |
| UBB | 7674 |
| PSMB2 | 7641 |
| NDC80 | 7594 |
| AHCTF1 | 7417 |
| LMNA | 7398 |
| CCNB1 | 7396 |
| PSMB11 | 7359 |
| TUBA8 | 7215 |
| PSMA6 | 7190 |
| BIRC5 | 7158 |
| RPS27A | 7120 |
| PSMA1 | 7018 |
| ANAPC11 | 6955 |
| SEH1L | 6838 |
| NUP35 | 6822 |
| TUBB8 | 6817 |
| BUB1 | 6792 |
| TUBB2B | 6768 |
| RAD21 | 6706 |
| LBR | 6693 |
| NUP85 | 6688 |
| PSMD3 | 6672 |
| CENPC | 6615 |
| VRK2 | 6403 |
| NUP37 | 6306 |
| ZW10 | 6123 |
| SKA2 | 6014 |
| NUP43 | 5921 |
| KNL1 | 5868 |
| ANAPC10 | 5865 |
| CKAP5 | 5856 |
| B9D2 | 5784 |
| CENPT | 5768 |
| PDS5B | 5760 |
| PSMC1 | 5715 |
| RAN | 5697 |
| CC2D1B | 5682 |
| SGO2 | 5675 |
| NUP54 | 5644 |
| PSMD2 | 5624 |
| PAFAH1B1 | 5441 |
| PSMA5 | 5362 |
| PLK1 | 5347 |
| ANAPC2 | 5346 |
| KIF2C | 5265 |
| SMC3 | 5251 |
| PSMA4 | 5246 |
| PSMC5 | 5193 |
| NUP107 | 5069 |
| RCC2 | 4920 |
| CDC20 | 4753 |
| RPS27 | 4711 |
| SPC25 | 4707 |
| NUP133 | 4676 |
| ANAPC5 | 4671 |
| FBXO5 | 4493 |
| KIF18A | 4448 |
| MAD2L1 | 4439 |
| KPNB1 | 4376 |
| NSL1 | 4358 |
| PSMF1 | 4311 |
| UBE2I | 4265 |
| PMF1 | 4232 |
| PSMD1 | 4227 |
| PSME3 | 4172 |
| CENPE | 4143 |
| PSMC2 | 4088 |
| TNPO1 | 4083 |
| CENPS | 4026 |
| CDCA8 | 3983 |
| PSMA8 | 3923 |
| PSMA7 | 3903 |
| PSME1 | 3866 |
| PSMA3 | 3850 |
| NUP205 | 3738 |
| MAPRE1 | 3644 |
| PSMB9 | 3459 |
| RCC1 | 3406 |
| PPP2R5C | 3398 |
| WAPL | 3291 |
| CENPF | 3253 |
| CDC27 | 3049 |
| PSMC4 | 3004 |
| NUF2 | 2983 |
| PSMC3 | 2960 |
| NUP93 | 2792 |
| NUP58 | 2703 |
| RANBP2 | 2651 |
| SEM1 | 2517 |
| CDC26 | 2306 |
| PPP2CA | 2292 |
| CHMP6 | 2240 |
| IST1 | 2232 |
| CHMP4A | 2193 |
| CCNB2 | 2043 |
| ANAPC15 | 1950 |
| CDC23 | 1927 |
| BUB3 | 1906 |
| SGO1 | 1729 |
| CENPK | 1710 |
| CHMP3 | 1707 |
| PPP2R2A | 1071 |
| ANKLE2 | 983 |
| TUBA4A | 938 |
| CDC16 | 754 |
| TUBA4B | 650 |
| NDEL1 | 641 |
| PSMD11 | 620 |
| PDS5A | 449 |
| PSMB8 | 447 |
| CHMP7 | 308 |
| DYNC1LI1 | 233 |
| MIS12 | 15 |
| PSMA2 | -85 |
| PPP2R5A | -152 |
| DYNC1I1 | -202 |
| ANAPC4 | -310 |
| NUP98 | -351 |
| DYNC1I2 | -440 |
| CHMP2A | -462 |
| TUBB1 | -584 |
| PSMD14 | -865 |
| CENPO | -914 |
| PSMD6 | -961 |
| SPDL1 | -977 |
| ANAPC1 | -1043 |
| XPO1 | -1083 |
| CHMP4B | -1102 |
| PSMB7 | -1294 |
| LMNB1 | -1316 |
| PTTG1 | -1320 |
| UBE2S | -1361 |
| NDC1 | -1433 |
| NUDC | -1567 |
| NUP188 | -1877 |
| CLASP1 | -2048 |
| PPP2R1A | -2107 |
| CENPN | -2163 |
| CLASP2 | -2170 |
| ZWILCH | -2190 |
| PSMB10 | -2290 |
| PSMB6 | -2408 |
| PPP2R5E | -2509 |
| SUMO1 | -2534 |
| UBE2C | -2539 |
| PSMD9 | -2570 |
| UBE2E1 | -2647 |
| PPP1CC | -3102 |
| LEMD2 | -3163 |
| CHMP2B | -3280 |
| STAG1 | -3331 |
| SPAST | -3426 |
| SPC24 | -3429 |
| DYNLL1 | -3541 |
| UBA52 | -3755 |
| ANAPC7 | -3780 |
| RANGAP1 | -3961 |
| TUBA1C | -4357 |
| TUBA1B | -4469 |
| ANAPC16 | -4502 |
| PSMB5 | -4687 |
| VPS4A | -5196 |
| PSMD7 | -5198 |
| TAOK1 | -5237 |
| TUBA3D | -5264 |
| INCENP | -5274 |
| PSMD4 | -5337 |
| UBE2D1 | -5394 |
| SEC13 | -5670 |
| NDE1 | -5839 |
| PSMB1 | -5858 |
| VRK1 | -5980 |
| MAD1L1 | -6006 |
| DYNC1H1 | -6092 |
| CDK1 | -6160 |
| CENPU | -6349 |
| TMPO | -6633 |
| SKA1 | -6910 |
| KIF2A | -6979 |
| CDCA5 | -7077 |
| NUP160 | -7169 |
| PPP2CB | -7216 |
| NUP62 | -7266 |
| TUBB4A | -7633 |
| PSMD8 | -7723 |
| CENPP | -7911 |
| TUBA1A | -8056 |
| PPP2R1B | -8245 |
| CENPH | -8704 |
| KIF2B | -8857 |
| TUBB2A | -9511 |
| PSMD5 | -9524 |
| CENPA | -9945 |
| TUBA3C | -10220 |
| TUBA3E | -10574 |
REACTOME_CELL_CYCLE_MITOTIC
| 1112 | |
|---|---|
| set | REACTOME_CELL_CYCLE_MITOTIC |
| setSize | 539 |
| pANOVA | 2.11e-05 |
| s.dist | 0.107 |
| p.adjustANOVA | 0.00122 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TUBG2 | 10998 |
| E2F1 | 10764 |
| CDKN2D | 10762 |
| H4C8 | 10752 |
| LIN52 | 10563 |
| CDK4 | 10506 |
| POLE3 | 10464 |
| CHMP4C | 10392 |
| POLD4 | 10382 |
| CENPQ | 10378 |
| PSMD12 | 10325 |
| CDKN2B | 10314 |
| DYNC1LI2 | 10216 |
| BANF1 | 10027 |
| USO1 | 9986 |
| PSMC6 | 9977 |
| ESPL1 | 9956 |
| KNTC1 | 9932 |
| H2AJ | 9870 |
| PSMB3 | 9858 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TUBG2 | 10998.0 |
| E2F1 | 10764.0 |
| CDKN2D | 10762.0 |
| H4C8 | 10752.0 |
| LIN52 | 10563.0 |
| CDK4 | 10506.0 |
| POLE3 | 10464.0 |
| CHMP4C | 10392.0 |
| POLD4 | 10382.0 |
| CENPQ | 10378.0 |
| PSMD12 | 10325.0 |
| CDKN2B | 10314.0 |
| DYNC1LI2 | 10216.0 |
| BANF1 | 10027.0 |
| USO1 | 9986.0 |
| PSMC6 | 9977.0 |
| ESPL1 | 9956.0 |
| KNTC1 | 9932.0 |
| H2AJ | 9870.0 |
| PSMB3 | 9858.0 |
| TUBG1 | 9820.0 |
| UBC | 9476.0 |
| DSN1 | 9391.0 |
| MCM2 | 9367.0 |
| RBX1 | 9293.0 |
| MCM10 | 9189.0 |
| LIN37 | 9132.0 |
| TUBB6 | 9058.0 |
| PPP2R5B | 9055.0 |
| H3C10 | 9015.0 |
| FEN1 | 9002.0 |
| GINS2 | 8991.0 |
| H3C11 | 8963.0 |
| POM121 | 8943.0 |
| ZWINT | 8928.0 |
| LEMD3 | 8915.0 |
| H4C12 | 8883.0 |
| BUB1B | 8870.0 |
| SSNA1 | 8831.0 |
| AURKB | 8795.0 |
| CSNK2B | 8721.0 |
| PPP2R5D | 8711.0 |
| ITGB3BP | 8707.0 |
| H4C2 | 8690.0 |
| PSME2 | 8685.0 |
| LYN | 8661.0 |
| H3-3A | 8639.0 |
| H2BC13 | 8609.0 |
| CDKN1B | 8453.0 |
| CCNH | 8435.0 |
| CKS1B | 8430.0 |
| H2BC1 | 8383.0 |
| CLIP1 | 8357.0 |
| TUBAL3 | 8355.0 |
| DYNLL2 | 8325.0 |
| DNA2 | 8298.0 |
| SIRT2 | 8280.0 |
| KIF23 | 8268.0 |
| PSMB4 | 8180.0 |
| TP53 | 8108.0 |
| NEK9 | 8080.0 |
| H3C12 | 8052.0 |
| CDC45 | 7992.0 |
| TUBB4B | 7956.0 |
| PSMD13 | 7901.0 |
| H2AZ2 | 7814.0 |
| TUBB3 | 7767.0 |
| NUP155 | 7761.0 |
| H2AC7 | 7754.5 |
| H2BC7 | 7754.5 |
| PPP1CB | 7737.0 |
| CENPM | 7709.0 |
| PSME4 | 7705.0 |
| CENPL | 7683.0 |
| UBB | 7674.0 |
| PSMB2 | 7641.0 |
| NDC80 | 7594.0 |
| CDC25A | 7593.0 |
| POLD1 | 7462.0 |
| KMT5A | 7432.0 |
| AHCTF1 | 7417.0 |
| LMNA | 7398.0 |
| CCNB1 | 7396.0 |
| PSMB11 | 7359.0 |
| CDKN2A | 7282.0 |
| H4C16 | 7260.0 |
| TUBA8 | 7215.0 |
| PSMA6 | 7190.0 |
| TPX2 | 7183.0 |
| BIRC5 | 7158.0 |
| RAB1B | 7123.0 |
| RPS27A | 7120.0 |
| MASTL | 7036.0 |
| CDC25C | 7020.0 |
| PSMA1 | 7018.0 |
| CCND3 | 6976.0 |
| ANAPC11 | 6955.0 |
| CDK2 | 6939.0 |
| RBBP4 | 6844.0 |
| SEH1L | 6838.0 |
| NUP35 | 6822.0 |
| TUBB8 | 6817.0 |
| ORC1 | 6803.0 |
| BUB1 | 6792.0 |
| TUBB2B | 6768.0 |
| NCAPG | 6722.0 |
| RAD21 | 6706.0 |
| LBR | 6693.0 |
| NUP85 | 6688.0 |
| PSMD3 | 6672.0 |
| H2AC8 | 6630.0 |
| CENPC | 6615.0 |
| MCM5 | 6536.0 |
| VRK2 | 6403.0 |
| NUP37 | 6306.0 |
| ZW10 | 6123.0 |
| H3-3B | 6110.0 |
| H2BC8 | 6087.0 |
| SKA2 | 6014.0 |
| AURKA | 5946.0 |
| H4C3 | 5935.0 |
| NUP43 | 5921.0 |
| KNL1 | 5868.0 |
| ANAPC10 | 5865.0 |
| H4C1 | 5864.0 |
| CKAP5 | 5856.0 |
| NEK2 | 5826.0 |
| DCTN2 | 5812.0 |
| B9D2 | 5784.0 |
| CENPT | 5768.0 |
| PDS5B | 5760.0 |
| RB1 | 5745.0 |
| PSMC1 | 5715.0 |
| MCM4 | 5708.0 |
| RAN | 5697.0 |
| CC2D1B | 5682.0 |
| SGO2 | 5675.0 |
| RPA1 | 5651.0 |
| NUP54 | 5644.0 |
| ESCO2 | 5634.0 |
| PSMD2 | 5624.0 |
| H3C1 | 5598.0 |
| NCAPD2 | 5528.0 |
| FOXM1 | 5480.0 |
| RAB8A | 5455.0 |
| PAFAH1B1 | 5441.0 |
| DYRK1A | 5435.0 |
| PSMA5 | 5362.0 |
| PLK1 | 5347.0 |
| ANAPC2 | 5346.0 |
| KIF2C | 5265.0 |
| SMC3 | 5251.0 |
| DBF4 | 5250.0 |
| PSMA4 | 5246.0 |
| CEP70 | 5241.0 |
| CDC14A | 5239.0 |
| PSMC5 | 5193.0 |
| H2BC5 | 5130.0 |
| RBL2 | 5110.0 |
| NUP107 | 5069.0 |
| CDKN1A | 5054.0 |
| CEP152 | 5016.0 |
| H4C6 | 4952.0 |
| RCC2 | 4920.0 |
| MCM3 | 4832.0 |
| PCNA | 4821.0 |
| NUP88 | 4788.0 |
| CDC20 | 4753.0 |
| H3C4 | 4718.0 |
| RPS27 | 4711.0 |
| SPC25 | 4707.0 |
| CSNK2A1 | 4697.0 |
| NUP133 | 4676.0 |
| ANAPC5 | 4671.0 |
| GINS1 | 4665.0 |
| H2BC3 | 4658.0 |
| TUBGCP2 | 4639.0 |
| H4C13 | 4630.0 |
| CEP135 | 4607.0 |
| ORC2 | 4592.0 |
| H4C11 | 4553.0 |
| FBXO5 | 4493.0 |
| KIF18A | 4448.0 |
| MAD2L1 | 4439.0 |
| KPNB1 | 4376.0 |
| NSL1 | 4358.0 |
| HMMR | 4352.0 |
| PSMF1 | 4311.0 |
| CCND2 | 4278.0 |
| UBE2I | 4265.0 |
| CDT1 | 4263.0 |
| NME7 | 4251.0 |
| PMF1 | 4232.0 |
| PSMD1 | 4227.0 |
| PSME3 | 4172.0 |
| CENPE | 4143.0 |
| CSNK2A2 | 4122.0 |
| PSMC2 | 4088.0 |
| TNPO1 | 4083.0 |
| CENPS | 4026.0 |
| E2F5 | 4024.0 |
| SMC2 | 3987.0 |
| CDCA8 | 3983.0 |
| H2BC10 | 3947.0 |
| PSMA8 | 3923.0 |
| PSMA7 | 3903.0 |
| PSME1 | 3866.0 |
| PSMA3 | 3850.0 |
| HSP90AB1 | 3811.0 |
| H4C4 | 3785.0 |
| NUP205 | 3738.0 |
| CABLES1 | 3701.0 |
| TOP2A | 3676.0 |
| MAPRE1 | 3644.0 |
| CCNA1 | 3593.0 |
| PRKCB | 3548.0 |
| SKP1 | 3534.0 |
| PRKACA | 3519.0 |
| CEP78 | 3480.0 |
| PSMB9 | 3459.0 |
| CDKN2C | 3429.0 |
| RCC1 | 3406.0 |
| PPP2R5C | 3398.0 |
| TFDP2 | 3339.0 |
| WAPL | 3291.0 |
| H2BC17 | 3276.0 |
| CENPF | 3253.0 |
| CCNE2 | 3190.0 |
| CSNK1D | 3179.0 |
| RFC2 | 3136.0 |
| ACTR1A | 3117.0 |
| SET | 3096.0 |
| POLE4 | 3064.0 |
| CDC27 | 3049.0 |
| H3C6 | 3009.0 |
| PSMC4 | 3004.0 |
| NUF2 | 2983.0 |
| PSMC3 | 2960.0 |
| H2AC6 | 2946.0 |
| PRIM1 | 2888.0 |
| NUP42 | 2844.0 |
| HAUS8 | 2809.0 |
| NUP93 | 2792.0 |
| MCM7 | 2717.0 |
| NUP58 | 2703.0 |
| H3C8 | 2699.0 |
| PHLDA1 | 2691.0 |
| RANBP2 | 2651.0 |
| PPME1 | 2529.0 |
| SEM1 | 2517.0 |
| H2AC4 | 2379.0 |
| CDC26 | 2306.0 |
| PPP2CA | 2292.0 |
| CHMP6 | 2240.0 |
| IST1 | 2232.0 |
| HAUS2 | 2201.0 |
| CHMP4A | 2193.0 |
| MCM8 | 2177.0 |
| CCNB2 | 2043.0 |
| H3-4 | 2030.0 |
| RAB1A | 1997.0 |
| ORC4 | 1976.0 |
| ANAPC15 | 1950.0 |
| CDC23 | 1927.0 |
| PPP1R12A | 1921.0 |
| BUB3 | 1906.0 |
| FBXL18 | 1900.0 |
| CENPJ | 1883.0 |
| CEP250 | 1760.0 |
| SGO1 | 1729.0 |
| CENPK | 1710.0 |
| CHMP3 | 1707.0 |
| HAUS5 | 1481.0 |
| CDC7 | 1479.0 |
| MYBL2 | 1460.0 |
| CCP110 | 1440.0 |
| H3C2 | 1438.0 |
| HSP90AA1 | 1355.0 |
| H2BC11 | 1338.0 |
| LIN9 | 1238.0 |
| NCAPH | 1206.0 |
| HAUS3 | 1201.0 |
| RPA2 | 1117.0 |
| PPP2R2A | 1071.0 |
| ANKLE2 | 983.0 |
| CEP63 | 968.0 |
| TUBA4A | 938.0 |
| MZT2A | 915.0 |
| RFC4 | 824.0 |
| CDC16 | 754.0 |
| YWHAE | 744.0 |
| ENSA | 708.0 |
| TUBA4B | 650.0 |
| NDEL1 | 641.0 |
| SDCCAG8 | 622.0 |
| PSMD11 | 620.0 |
| CNEP1R1 | 520.0 |
| H2AX | 499.0 |
| NEK7 | 461.0 |
| TUBGCP6 | 457.0 |
| PDS5A | 449.0 |
| PSMB8 | 447.0 |
| POLD2 | 347.0 |
| HDAC1 | 346.0 |
| CHMP7 | 308.0 |
| H2BC15 | 240.0 |
| DYNC1LI1 | 233.0 |
| BTRC | 216.0 |
| DCTN3 | 114.0 |
| POLE2 | 60.0 |
| ORC3 | 36.0 |
| FZR1 | 16.0 |
| MIS12 | 15.0 |
| MCM6 | 2.0 |
| POLA2 | -22.0 |
| FKBPL | -24.0 |
| RFC5 | -81.0 |
| PSMA2 | -85.0 |
| PPP2R5A | -152.0 |
| PCM1 | -170.0 |
| HAUS1 | -189.0 |
| DYNC1I1 | -202.0 |
| ANAPC4 | -310.0 |
| KIF20A | -330.0 |
| NUP98 | -351.0 |
| H2AZ1 | -360.0 |
| DYNC1I2 | -440.0 |
| CHMP2A | -462.0 |
| H3C3 | -546.0 |
| TUBB1 | -584.0 |
| ORC5 | -617.0 |
| RBL1 | -621.0 |
| E2F6 | -673.0 |
| H2AC20 | -674.0 |
| HAUS4 | -693.0 |
| MNAT1 | -717.0 |
| OPTN | -719.0 |
| GMNN | -730.0 |
| RAB2A | -745.0 |
| CEP41 | -791.0 |
| MAPK1 | -857.0 |
| PSMD14 | -865.0 |
| CENPO | -914.0 |
| GINS4 | -959.0 |
| PSMD6 | -961.0 |
| CCND1 | -962.0 |
| FBXW11 | -964.0 |
| NEK6 | -969.0 |
| SPDL1 | -977.0 |
| AKAP9 | -1032.0 |
| ANAPC1 | -1043.0 |
| XPO1 | -1083.0 |
| CHMP4B | -1102.0 |
| CEP72 | -1128.0 |
| CDK6 | -1199.0 |
| PSMB7 | -1294.0 |
| LMNB1 | -1316.0 |
| PTTG1 | -1320.0 |
| BLZF1 | -1356.0 |
| UBE2S | -1361.0 |
| H2BC6 | -1396.0 |
| NDC1 | -1433.0 |
| LIG1 | -1478.0 |
| ESCO1 | -1480.0 |
| MAX | -1557.0 |
| NUDC | -1567.0 |
| PPP2R2D | -1687.0 |
| NUP188 | -1877.0 |
| YWHAG | -1887.0 |
| SMC4 | -1946.0 |
| CLASP1 | -2048.0 |
| H2BC4 | -2094.0 |
| PPP2R1A | -2107.0 |
| H2BC12 | -2115.0 |
| CEP290 | -2146.0 |
| TFDP1 | -2156.0 |
| CENPN | -2163.0 |
| CLASP2 | -2170.0 |
| ZWILCH | -2190.0 |
| GORASP2 | -2197.0 |
| TUBB | -2261.0 |
| PSMB10 | -2290.0 |
| CTDNEP1 | -2338.0 |
| E2F3 | -2343.0 |
| EP300 | -2354.0 |
| ODF2 | -2377.0 |
| PSMB6 | -2408.0 |
| JAK2 | -2410.0 |
| CUL1 | -2437.0 |
| LPIN2 | -2453.0 |
| CDK11B | -2458.0 |
| MZT1 | -2477.0 |
| AKT2 | -2480.0 |
| PPP2R5E | -2509.0 |
| SUMO1 | -2534.0 |
| UBE2C | -2539.0 |
| AKT1 | -2548.0 |
| PSMD9 | -2570.0 |
| MYC | -2593.0 |
| UBE2E1 | -2647.0 |
| TYMS | -2661.0 |
| SFI1 | -2689.0 |
| NCAPG2 | -2771.0 |
| AAAS | -2839.0 |
| CDC25B | -3069.0 |
| CEP57 | -3092.0 |
| PPP1CC | -3102.0 |
| LCMT1 | -3145.0 |
| LEMD2 | -3163.0 |
| PRKCA | -3175.0 |
| PRKAR2B | -3186.0 |
| CHMP2B | -3280.0 |
| GORASP1 | -3300.0 |
| STAG1 | -3331.0 |
| WEE1 | -3415.0 |
| NUP153 | -3416.0 |
| SPAST | -3426.0 |
| SPC24 | -3429.0 |
| NCAPD3 | -3452.0 |
| ORC6 | -3467.0 |
| DHFR | -3474.0 |
| CCNA2 | -3495.0 |
| RAE1 | -3503.0 |
| DYNLL1 | -3541.0 |
| GTSE1 | -3549.0 |
| EML4 | -3716.0 |
| UBA52 | -3755.0 |
| PKMYT1 | -3762.0 |
| ANAPC7 | -3780.0 |
| LPIN1 | -3821.0 |
| ALMS1 | -3856.0 |
| FBXL7 | -3927.0 |
| RANGAP1 | -3961.0 |
| RFC1 | -3990.0 |
| AJUBA | -4043.0 |
| POM121C | -4045.0 |
| CDKN1C | -4120.0 |
| SRC | -4161.0 |
| TUBGCP5 | -4190.0 |
| NEDD1 | -4195.0 |
| PLK4 | -4251.0 |
| E2F2 | -4314.0 |
| TUBA1C | -4357.0 |
| CEP43 | -4402.0 |
| LIN54 | -4429.0 |
| BORA | -4440.0 |
| TUBA1B | -4469.0 |
| ANAPC16 | -4502.0 |
| PSMB5 | -4687.0 |
| CEP192 | -4704.0 |
| SKP2 | -4745.0 |
| CNTRL | -4773.0 |
| H2BC9 | -4907.5 |
| H3C7 | -4907.5 |
| CDK7 | -4917.0 |
| H4C5 | -4941.0 |
| RFC3 | -4967.0 |
| RRM2 | -4995.0 |
| VPS4A | -5196.0 |
| PSMD7 | -5198.0 |
| TAOK1 | -5237.0 |
| TUBA3D | -5264.0 |
| INCENP | -5274.0 |
| CEP76 | -5319.0 |
| PSMD4 | -5337.0 |
| UBE2D1 | -5394.0 |
| DCTN1 | -5418.0 |
| POLD3 | -5419.0 |
| MAPK3 | -5444.0 |
| NUP214 | -5472.0 |
| CEP131 | -5479.0 |
| AKT3 | -5586.0 |
| SEC13 | -5670.0 |
| CDK11A | -5719.0 |
| H2BC21 | -5773.0 |
| NDE1 | -5839.0 |
| PSMB1 | -5858.0 |
| VRK1 | -5980.0 |
| MCPH1 | -5981.0 |
| MAD1L1 | -6006.0 |
| GSK3B | -6007.0 |
| DYNC1H1 | -6092.0 |
| PRIM2 | -6159.0 |
| CDK1 | -6160.0 |
| GOLGA2 | -6181.0 |
| NUP50 | -6183.0 |
| CENPU | -6349.0 |
| PPP1R12B | -6357.0 |
| CDK5RAP2 | -6528.0 |
| TMPO | -6633.0 |
| NUP210 | -6637.0 |
| H2BC26 | -6695.0 |
| E2F4 | -6771.0 |
| NUMA1 | -6909.0 |
| SKA1 | -6910.0 |
| MAU2 | -6927.0 |
| KIF2A | -6979.0 |
| CDCA5 | -7077.0 |
| NUP160 | -7169.0 |
| PPP2CB | -7216.0 |
| NUP62 | -7266.0 |
| TUBGCP3 | -7341.0 |
| ARPP19 | -7351.0 |
| CDC6 | -7443.0 |
| PCNT | -7476.0 |
| CSNK1E | -7527.0 |
| PTK6 | -7557.0 |
| TUBB4A | -7633.0 |
| CEP164 | -7712.0 |
| PSMD8 | -7723.0 |
| NCAPH2 | -7762.0 |
| CENPP | -7911.0 |
| NIPBL | -7970.0 |
| TUBGCP4 | -7988.0 |
| GINS3 | -7990.0 |
| TUBA1A | -8056.0 |
| RPA3 | -8086.0 |
| NINL | -8186.0 |
| PPP2R1B | -8245.0 |
| ABL1 | -8289.0 |
| POLE | -8297.0 |
| H2AC14 | -8606.0 |
| HAUS6 | -8616.0 |
| CENPH | -8704.0 |
| H2BC14 | -8730.0 |
| MZT2B | -8774.0 |
| KIF2B | -8857.0 |
| LPIN3 | -8997.0 |
| TPR | -9043.0 |
| H4C9 | -9282.0 |
| TUBB2A | -9511.0 |
| PSMD5 | -9524.0 |
| TK1 | -9564.0 |
| CCNE1 | -9930.0 |
| CENPA | -9945.0 |
| TUBA3C | -10220.0 |
| H2AC18 | -10224.5 |
| H2AC19 | -10224.5 |
| TUBA3E | -10574.0 |
REACTOME_G2_M_CHECKPOINTS
| 1116 | |
|---|---|
| set | REACTOME_G2_M_CHECKPOINTS |
| setSize | 162 |
| pANOVA | 2.21e-05 |
| s.dist | 0.193 |
| p.adjustANOVA | 0.00122 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| H4C8 | 10752 |
| PSMD12 | 10325 |
| PSMC6 | 9977 |
| PSMB3 | 9858 |
| UBC | 9476 |
| MCM2 | 9367 |
| BABAM1 | 9283 |
| RAD1 | 9237 |
| KAT5 | 9221 |
| MCM10 | 9189 |
| H4C12 | 8883 |
| H4C2 | 8690 |
| PSME2 | 8685 |
| BARD1 | 8638 |
| H2BC13 | 8609 |
| H2BC1 | 8383 |
| DNA2 | 8298 |
| PSMB4 | 8180 |
| TP53 | 8108 |
| CDC45 | 7992 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| H4C8 | 10752.0 |
| PSMD12 | 10325.0 |
| PSMC6 | 9977.0 |
| PSMB3 | 9858.0 |
| UBC | 9476.0 |
| MCM2 | 9367.0 |
| BABAM1 | 9283.0 |
| RAD1 | 9237.0 |
| KAT5 | 9221.0 |
| MCM10 | 9189.0 |
| H4C12 | 8883.0 |
| H4C2 | 8690.0 |
| PSME2 | 8685.0 |
| BARD1 | 8638.0 |
| H2BC13 | 8609.0 |
| H2BC1 | 8383.0 |
| DNA2 | 8298.0 |
| PSMB4 | 8180.0 |
| TP53 | 8108.0 |
| CDC45 | 7992.0 |
| PSMD13 | 7901.0 |
| RBBP8 | 7822.0 |
| H2BC7 | 7754.5 |
| PSME4 | 7705.0 |
| UBB | 7674.0 |
| PSMB2 | 7641.0 |
| CDC25A | 7593.0 |
| CCNB1 | 7396.0 |
| ABRAXAS1 | 7372.0 |
| PSMB11 | 7359.0 |
| H4C16 | 7260.0 |
| PSMA6 | 7190.0 |
| RPS27A | 7120.0 |
| CDC25C | 7020.0 |
| PSMA1 | 7018.0 |
| CDK2 | 6939.0 |
| CHEK1 | 6909.0 |
| ORC1 | 6803.0 |
| PSMD3 | 6672.0 |
| MDC1 | 6671.0 |
| RHNO1 | 6649.0 |
| RAD9A | 6635.0 |
| MCM5 | 6536.0 |
| RNF8 | 6146.0 |
| H2BC8 | 6087.0 |
| H4C3 | 5935.0 |
| YWHAB | 5879.0 |
| H4C1 | 5864.0 |
| PSMC1 | 5715.0 |
| MCM4 | 5708.0 |
| RPA1 | 5651.0 |
| PSMD2 | 5624.0 |
| MRE11 | 5620.0 |
| PSMA5 | 5362.0 |
| DBF4 | 5250.0 |
| PSMA4 | 5246.0 |
| PSMC5 | 5193.0 |
| H2BC5 | 5130.0 |
| H4C6 | 4952.0 |
| MCM3 | 4832.0 |
| H2BC3 | 4658.0 |
| YWHAZ | 4655.0 |
| H4C13 | 4630.0 |
| BRIP1 | 4606.0 |
| ATM | 4600.0 |
| ORC2 | 4592.0 |
| H4C11 | 4553.0 |
| PSMF1 | 4311.0 |
| BLM | 4237.0 |
| PSMD1 | 4227.0 |
| PSME3 | 4172.0 |
| PSMC2 | 4088.0 |
| H2BC10 | 3947.0 |
| PSMA8 | 3923.0 |
| PSMA7 | 3903.0 |
| PSME1 | 3866.0 |
| PSMA3 | 3850.0 |
| H4C4 | 3785.0 |
| EXO1 | 3595.0 |
| PSMB9 | 3459.0 |
| CHEK2 | 3413.0 |
| HUS1 | 3387.0 |
| H2BC17 | 3276.0 |
| RFC2 | 3136.0 |
| PSMC4 | 3004.0 |
| PSMC3 | 2960.0 |
| MCM7 | 2717.0 |
| YWHAH | 2697.0 |
| SEM1 | 2517.0 |
| UBE2N | 2342.0 |
| MCM8 | 2177.0 |
| CCNB2 | 2043.0 |
| H3-4 | 2030.0 |
| ORC4 | 1976.0 |
| CDC7 | 1479.0 |
| H2BC11 | 1338.0 |
| BRCA1 | 1120.0 |
| RPA2 | 1117.0 |
| RFC4 | 824.0 |
| YWHAE | 744.0 |
| PSMD11 | 620.0 |
| H2AX | 499.0 |
| PSMB8 | 447.0 |
| YWHAQ | 336.0 |
| RAD17 | 283.0 |
| TOP3A | 244.0 |
| H2BC15 | 240.0 |
| UIMC1 | 46.0 |
| RAD9B | 45.0 |
| ORC3 | 36.0 |
| MCM6 | 2.0 |
| RFC5 | -81.0 |
| PSMA2 | -85.0 |
| NSD2 | -277.0 |
| RMI1 | -315.0 |
| UBE2V2 | -500.0 |
| ORC5 | -617.0 |
| PSMD14 | -865.0 |
| PSMD6 | -961.0 |
| PSMB7 | -1294.0 |
| H2BC6 | -1396.0 |
| YWHAG | -1887.0 |
| H2BC4 | -2094.0 |
| H2BC12 | -2115.0 |
| TP53BP1 | -2175.0 |
| PSMB10 | -2290.0 |
| PSMB6 | -2408.0 |
| PIAS4 | -2542.0 |
| PSMD9 | -2570.0 |
| CLSPN | -2700.0 |
| WRN | -2909.0 |
| HERC2 | -3058.0 |
| WEE1 | -3415.0 |
| ORC6 | -3467.0 |
| GTSE1 | -3549.0 |
| RMI2 | -3754.0 |
| UBA52 | -3755.0 |
| PKMYT1 | -3762.0 |
| NBN | -3893.0 |
| ATR | -4506.0 |
| PSMB5 | -4687.0 |
| H2BC9 | -4907.5 |
| H4C5 | -4941.0 |
| RFC3 | -4967.0 |
| PSMD7 | -5198.0 |
| ATRIP | -5201.0 |
| RNF168 | -5219.0 |
| PSMD4 | -5337.0 |
| H2BC21 | -5773.0 |
| TOPBP1 | -5800.0 |
| PSMB1 | -5858.0 |
| BABAM2 | -6094.0 |
| CDK1 | -6160.0 |
| RAD50 | -6431.0 |
| H2BC26 | -6695.0 |
| CDC6 | -7443.0 |
| PSMD8 | -7723.0 |
| RPA3 | -8086.0 |
| H2BC14 | -8730.0 |
| H4C9 | -9282.0 |
| SFN | -9368.0 |
| PSMD5 | -9524.0 |
REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE
| 1082 | |
|---|---|
| set | REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE |
| setSize | 125 |
| pANOVA | 2.27e-05 |
| s.dist | -0.219 |
| p.adjustANOVA | 0.00122 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| SPRR1B | -10519 |
| KRT74 | -10488 |
| SPRR2G | -10487 |
| KRT39 | -10470 |
| LCE2B | -10453 |
| LIPJ | -10321 |
| LCE5A | -10173 |
| KRT35 | -10044 |
| KRT77 | -9944 |
| FLG | -9873 |
| KRT78 | -9854 |
| KRT6A | -9852 |
| DSC2 | -9840 |
| KRT17 | -9751 |
| KRT16 | -9747 |
| LIPK | -9713 |
| KRT33B | -9332 |
| KRT15 | -9145 |
| RPTN | -9099 |
| KRT86 | -9053 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SPRR1B | -10519 |
| KRT74 | -10488 |
| SPRR2G | -10487 |
| KRT39 | -10470 |
| LCE2B | -10453 |
| LIPJ | -10321 |
| LCE5A | -10173 |
| KRT35 | -10044 |
| KRT77 | -9944 |
| FLG | -9873 |
| KRT78 | -9854 |
| KRT6A | -9852 |
| DSC2 | -9840 |
| KRT17 | -9751 |
| KRT16 | -9747 |
| LIPK | -9713 |
| KRT33B | -9332 |
| KRT15 | -9145 |
| RPTN | -9099 |
| KRT86 | -9053 |
| KRT79 | -8946 |
| SPINK5 | -8934 |
| JUP | -8895 |
| TGM1 | -8871 |
| KRT76 | -8415 |
| LCE3E | -8327 |
| FURIN | -8263 |
| DSC3 | -8239 |
| KRT40 | -8214 |
| KRT23 | -7989 |
| KRT33A | -7949 |
| KRT80 | -7834 |
| KAZN | -7793 |
| SPRR3 | -7737 |
| SPRR1A | -7639 |
| KLK5 | -7558 |
| KRT82 | -7532 |
| LCE1F | -7531 |
| KLK12 | -7525 |
| LCE1E | -7473 |
| KRT81 | -7335 |
| KRT71 | -7230 |
| LCE6A | -7226 |
| LIPM | -6977 |
| KRT83 | -6862 |
| PRSS8 | -6817 |
| PKP3 | -6551 |
| PKP2 | -6492 |
| KRT37 | -6465 |
| PKP4 | -6335 |
| LCE1C | -6142 |
| KRT2 | -5926 |
| DSG1 | -5553 |
| EVPL | -5510 |
| KRT34 | -5259 |
| CSTA | -5194 |
| KRT5 | -5141 |
| KRT19 | -5105 |
| KRT84 | -4820 |
| KRT38 | -4663 |
| KRT6B | -4497 |
| KRT7 | -4448 |
| PPL | -4353 |
| LCE3D | -4344 |
| PKP1 | -4060 |
| KRT10 | -3899 |
| LCE1B | -3580 |
| DSG3 | -3430 |
| SPINK6 | -3095 |
| KLK8 | -3085 |
| CAPNS1 | -3016 |
| PCSK6 | -2712 |
| KRT75 | -2326 |
| KRT1 | -2294 |
| KRT28 | -2109 |
| TGM5 | -1540 |
| SPINK9 | -1467 |
| LCE2A | -1431 |
| KRT12 | -1192 |
| KRT18 | -1134 |
| KRT31 | -670 |
| KRT24 | -436 |
| KRT85 | -171 |
| DSC1 | 798 |
| KRT14 | 879 |
| KRT6C | 935 |
| LCE3B | 1042 |
| KRT73 | 1249 |
| KRT8 | 2185 |
| CASP14 | 2223 |
| CAPN1 | 3476 |
| ST14 | 3539 |
| DSP | 3665 |
| CELA2A | 4115 |
| KRT13 | 4121 |
| CDSN | 4457 |
| KLK14 | 4459 |
| LCE4A | 4531 |
| SPRR2F | 4582 |
| SPRR2A | 4601 |
| DSG4 | 4743 |
| KRT27 | 4777 |
| KRT4 | 5006 |
| LCE2D | 5612 |
| KRT3 | 5654 |
| KRT26 | 6394 |
| KRT36 | 6496 |
| KLK13 | 7082 |
| KRT25 | 7176 |
| IVL | 7250 |
| KRT32 | 7872 |
| LCE1A | 8003 |
| SPRR2D | 8726 |
| DSG2 | 8780 |
| PERP | 9660 |
| LELP1 | 9994 |
| KRT20 | 10084 |
| TCHH | 10142 |
| LCE2C | 10180 |
| LCE3A | 10442 |
| KRT9 | 10562 |
| KRT72 | 10578 |
| LIPN | 10639 |
| PI3 | 10905 |
| SPRR2E | 11070 |
REACTOME_CELLULAR_SENESCENCE
| 503 | |
|---|---|
| set | REACTOME_CELLULAR_SENESCENCE |
| setSize | 189 |
| pANOVA | 2.31e-05 |
| s.dist | 0.179 |
| p.adjustANOVA | 0.00122 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| H1-0 | 10953 |
| E2F1 | 10764 |
| CDKN2D | 10762 |
| H4C8 | 10752 |
| CDK4 | 10506 |
| CDKN2B | 10314 |
| AGO1 | 10212 |
| SUZ12 | 10134 |
| ID1 | 10059 |
| H2AJ | 9870 |
| H1-3 | 9718 |
| JUN | 9609 |
| CXCL8 | 9558 |
| UBC | 9476 |
| STAT3 | 9471 |
| MIR24-2 | 9434 |
| KAT5 | 9221 |
| IL6 | 9220 |
| ERF | 9089 |
| H3C10 | 9015 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| H1-0 | 10953.0 |
| E2F1 | 10764.0 |
| CDKN2D | 10762.0 |
| H4C8 | 10752.0 |
| CDK4 | 10506.0 |
| CDKN2B | 10314.0 |
| AGO1 | 10212.0 |
| SUZ12 | 10134.0 |
| ID1 | 10059.0 |
| H2AJ | 9870.0 |
| H1-3 | 9718.0 |
| JUN | 9609.0 |
| CXCL8 | 9558.0 |
| UBC | 9476.0 |
| STAT3 | 9471.0 |
| MIR24-2 | 9434.0 |
| KAT5 | 9221.0 |
| IL6 | 9220.0 |
| ERF | 9089.0 |
| H3C10 | 9015.0 |
| TXN | 8969.0 |
| H3C11 | 8963.0 |
| H4C12 | 8883.0 |
| MAPK14 | 8739.0 |
| H4C2 | 8690.0 |
| H3-3A | 8639.0 |
| H2BC13 | 8609.0 |
| MDM4 | 8496.0 |
| CDKN1B | 8453.0 |
| H2BC1 | 8383.0 |
| ASF1A | 8338.0 |
| TP53 | 8108.0 |
| H3C12 | 8052.0 |
| H2AZ2 | 7814.0 |
| H2AC7 | 7754.5 |
| H2BC7 | 7754.5 |
| VENTX | 7728.0 |
| MAP2K3 | 7685.0 |
| UBB | 7674.0 |
| CDKN2A | 7282.0 |
| H4C16 | 7260.0 |
| RPS27A | 7120.0 |
| KDM6B | 7004.0 |
| ANAPC11 | 6955.0 |
| CDK2 | 6939.0 |
| RBBP4 | 6844.0 |
| H2AC8 | 6630.0 |
| MAP2K7 | 6542.0 |
| ETS1 | 6283.0 |
| MOV10 | 6170.0 |
| H3-3B | 6110.0 |
| H2BC8 | 6087.0 |
| H4C3 | 5935.0 |
| ANAPC10 | 5865.0 |
| H4C1 | 5864.0 |
| RB1 | 5745.0 |
| MRE11 | 5620.0 |
| H3C1 | 5598.0 |
| AGO4 | 5459.0 |
| ANAPC2 | 5346.0 |
| H1-5 | 5307.0 |
| PHC1 | 5291.0 |
| HIRA | 5256.0 |
| H2BC5 | 5130.0 |
| HMGA2 | 5097.0 |
| CDKN1A | 5054.0 |
| H4C6 | 4952.0 |
| TERF2 | 4935.0 |
| H1-2 | 4724.0 |
| H3C4 | 4718.0 |
| CEBPB | 4682.0 |
| BMI1 | 4673.0 |
| ANAPC5 | 4671.0 |
| H2BC3 | 4658.0 |
| H4C13 | 4630.0 |
| ATM | 4600.0 |
| H4C11 | 4553.0 |
| RPS6KA1 | 4484.0 |
| MAP3K5 | 4207.0 |
| TNRC6B | 4201.0 |
| MAPKAPK2 | 4162.0 |
| H2BC10 | 3947.0 |
| H4C4 | 3785.0 |
| CBX2 | 3753.0 |
| CCNA1 | 3593.0 |
| MAPK9 | 3453.0 |
| CDKN2C | 3429.0 |
| TFDP2 | 3339.0 |
| H2BC17 | 3276.0 |
| H1-4 | 3207.0 |
| CCNE2 | 3190.0 |
| CDC27 | 3049.0 |
| H3C6 | 3009.0 |
| H2AC6 | 2946.0 |
| EHMT1 | 2779.0 |
| H3C8 | 2699.0 |
| CBX6 | 2581.0 |
| H2AC4 | 2379.0 |
| CDC26 | 2306.0 |
| FOS | 2247.0 |
| MAPKAPK5 | 2167.0 |
| H3-4 | 2030.0 |
| ANAPC15 | 1950.0 |
| CDC23 | 1927.0 |
| TNIK | 1815.0 |
| MAPKAPK3 | 1801.0 |
| TINF2 | 1779.0 |
| IL1A | 1611.0 |
| RING1 | 1572.0 |
| ETS2 | 1483.0 |
| H3C2 | 1438.0 |
| CBX8 | 1425.0 |
| H2BC11 | 1338.0 |
| EHMT2 | 1321.0 |
| MAP4K4 | 1194.0 |
| CDC16 | 754.0 |
| H2AX | 499.0 |
| H2BC15 | 240.0 |
| MDM2 | 219.0 |
| CBX4 | 205.0 |
| EED | 94.0 |
| FZR1 | 16.0 |
| ANAPC4 | -310.0 |
| H2AZ1 | -360.0 |
| HMGA1 | -496.0 |
| H3C3 | -546.0 |
| POT1 | -662.0 |
| H2AC20 | -674.0 |
| MAPK1 | -857.0 |
| ANAPC1 | -1043.0 |
| UBN1 | -1139.0 |
| CDK6 | -1199.0 |
| LMNB1 | -1316.0 |
| MAPK7 | -1357.0 |
| UBE2S | -1361.0 |
| H2BC6 | -1396.0 |
| AGO3 | -1413.0 |
| ACD | -1494.5 |
| MAP2K4 | -2008.0 |
| MAP2K6 | -2038.0 |
| H2BC4 | -2094.0 |
| H2BC12 | -2115.0 |
| TFDP1 | -2156.0 |
| MAPK11 | -2236.0 |
| E2F3 | -2343.0 |
| EZH2 | -2415.0 |
| TNRC6A | -2432.0 |
| UBE2C | -2539.0 |
| UBE2E1 | -2647.0 |
| RPS6KA2 | -2842.0 |
| TERF1 | -3138.0 |
| SP1 | -3275.0 |
| MAPK10 | -3279.0 |
| PHC3 | -3360.0 |
| CCNA2 | -3495.0 |
| IFNB1 | -3599.0 |
| TNRC6C | -3711.0 |
| UBA52 | -3755.0 |
| ANAPC7 | -3780.0 |
| NBN | -3893.0 |
| TERF2IP | -3905.0 |
| SCMH1 | -3933.0 |
| E2F2 | -4314.0 |
| EP400 | -4349.0 |
| ANAPC16 | -4502.0 |
| H2BC9 | -4907.5 |
| H3C7 | -4907.5 |
| H4C5 | -4941.0 |
| UBE2D1 | -5394.0 |
| MAPK3 | -5444.0 |
| H2BC21 | -5773.0 |
| CABIN1 | -6185.0 |
| RAD50 | -6431.0 |
| RNF2 | -6542.0 |
| H2BC26 | -6695.0 |
| PHC2 | -6705.0 |
| NFKB1 | -7273.0 |
| IGFBP7 | -7794.0 |
| RELA | -8093.0 |
| H1-1 | -8290.0 |
| H2AC14 | -8606.0 |
| MAPK8 | -8692.0 |
| H2BC14 | -8730.0 |
| MIR24-1 | -9122.0 |
| MINK1 | -9125.0 |
| H4C9 | -9282.0 |
| CCNE1 | -9930.0 |
| H2AC18 | -10224.5 |
| H2AC19 | -10224.5 |
REACTOME_DNA_REPLICATION_PRE_INITIATION
| 1101 | |
|---|---|
| set | REACTOME_DNA_REPLICATION_PRE_INITIATION |
| setSize | 150 |
| pANOVA | 2.41e-05 |
| s.dist | 0.2 |
| p.adjustANOVA | 0.00124 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| H4C8 | 10752 |
| POLE3 | 10464 |
| PSMD12 | 10325 |
| PSMC6 | 9977 |
| H2AJ | 9870 |
| PSMB3 | 9858 |
| UBC | 9476 |
| MCM2 | 9367 |
| MCM10 | 9189 |
| H3C10 | 9015 |
| H3C11 | 8963 |
| H4C12 | 8883 |
| H4C2 | 8690 |
| KPNA6 | 8687 |
| PSME2 | 8685 |
| H3-3A | 8639 |
| H2BC13 | 8609 |
| H2BC1 | 8383 |
| PSMB4 | 8180 |
| H3C12 | 8052 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| H4C8 | 10752.0 |
| POLE3 | 10464.0 |
| PSMD12 | 10325.0 |
| PSMC6 | 9977.0 |
| H2AJ | 9870.0 |
| PSMB3 | 9858.0 |
| UBC | 9476.0 |
| MCM2 | 9367.0 |
| MCM10 | 9189.0 |
| H3C10 | 9015.0 |
| H3C11 | 8963.0 |
| H4C12 | 8883.0 |
| H4C2 | 8690.0 |
| KPNA6 | 8687.0 |
| PSME2 | 8685.0 |
| H3-3A | 8639.0 |
| H2BC13 | 8609.0 |
| H2BC1 | 8383.0 |
| PSMB4 | 8180.0 |
| H3C12 | 8052.0 |
| CDC45 | 7992.0 |
| PSMD13 | 7901.0 |
| H2AZ2 | 7814.0 |
| H2AC7 | 7754.5 |
| H2BC7 | 7754.5 |
| UBB | 7674.0 |
| PSMB2 | 7641.0 |
| H4C16 | 7260.0 |
| PSMA6 | 7190.0 |
| RPS27A | 7120.0 |
| PSMA1 | 7018.0 |
| ANAPC11 | 6955.0 |
| CDK2 | 6939.0 |
| ORC1 | 6803.0 |
| PSMD3 | 6672.0 |
| H2AC8 | 6630.0 |
| MCM5 | 6536.0 |
| H3-3B | 6110.0 |
| H2BC8 | 6087.0 |
| H4C3 | 5935.0 |
| ANAPC10 | 5865.0 |
| H4C1 | 5864.0 |
| PSMC1 | 5715.0 |
| MCM4 | 5708.0 |
| RPA1 | 5651.0 |
| PSMD2 | 5624.0 |
| H3C1 | 5598.0 |
| PSMA5 | 5362.0 |
| ANAPC2 | 5346.0 |
| DBF4 | 5250.0 |
| PSMA4 | 5246.0 |
| PSMC5 | 5193.0 |
| H2BC5 | 5130.0 |
| H4C6 | 4952.0 |
| MCM3 | 4832.0 |
| H3C4 | 4718.0 |
| ANAPC5 | 4671.0 |
| H2BC3 | 4658.0 |
| H4C13 | 4630.0 |
| ORC2 | 4592.0 |
| H4C11 | 4553.0 |
| KPNB1 | 4376.0 |
| PSMF1 | 4311.0 |
| CDT1 | 4263.0 |
| PSMD1 | 4227.0 |
| PSME3 | 4172.0 |
| PSMC2 | 4088.0 |
| H2BC10 | 3947.0 |
| PSMA7 | 3903.0 |
| PSME1 | 3866.0 |
| PSMA3 | 3850.0 |
| H4C4 | 3785.0 |
| PSMB9 | 3459.0 |
| KPNA1 | 3308.0 |
| H2BC17 | 3276.0 |
| POLE4 | 3064.0 |
| CDC27 | 3049.0 |
| H3C6 | 3009.0 |
| PSMC4 | 3004.0 |
| PSMC3 | 2960.0 |
| H2AC6 | 2946.0 |
| PRIM1 | 2888.0 |
| MCM7 | 2717.0 |
| H3C8 | 2699.0 |
| SEM1 | 2517.0 |
| H2AC4 | 2379.0 |
| CDC26 | 2306.0 |
| MCM8 | 2177.0 |
| ORC4 | 1976.0 |
| ANAPC15 | 1950.0 |
| CDC23 | 1927.0 |
| CDC7 | 1479.0 |
| H3C2 | 1438.0 |
| H2BC11 | 1338.0 |
| RPA2 | 1117.0 |
| CDC16 | 754.0 |
| PSMD11 | 620.0 |
| H2AX | 499.0 |
| PSMB8 | 447.0 |
| H2BC15 | 240.0 |
| POLE2 | 60.0 |
| ORC3 | 36.0 |
| FZR1 | 16.0 |
| MCM6 | 2.0 |
| POLA2 | -22.0 |
| PSMA2 | -85.0 |
| ANAPC4 | -310.0 |
| H2AZ1 | -360.0 |
| H3C3 | -546.0 |
| ORC5 | -617.0 |
| H2AC20 | -674.0 |
| GMNN | -730.0 |
| PSMD14 | -865.0 |
| PSMD6 | -961.0 |
| ANAPC1 | -1043.0 |
| PSMB7 | -1294.0 |
| UBE2S | -1361.0 |
| H2BC6 | -1396.0 |
| H2BC4 | -2094.0 |
| H2BC12 | -2115.0 |
| PSMB10 | -2290.0 |
| PSMB6 | -2408.0 |
| UBE2C | -2539.0 |
| PSMD9 | -2570.0 |
| UBE2E1 | -2647.0 |
| ORC6 | -3467.0 |
| UBA52 | -3755.0 |
| ANAPC7 | -3780.0 |
| ANAPC16 | -4502.0 |
| PSMB5 | -4687.0 |
| H2BC9 | -4907.5 |
| H3C7 | -4907.5 |
| H4C5 | -4941.0 |
| PSMD7 | -5198.0 |
| PSMD4 | -5337.0 |
| UBE2D1 | -5394.0 |
| H2BC21 | -5773.0 |
| PSMB1 | -5858.0 |
| PRIM2 | -6159.0 |
| H2BC26 | -6695.0 |
| CDC6 | -7443.0 |
| PSMD8 | -7723.0 |
| RPA3 | -8086.0 |
| POLE | -8297.0 |
| H2AC14 | -8606.0 |
| H2BC14 | -8730.0 |
| H4C9 | -9282.0 |
| PSMD5 | -9524.0 |
| H2AC18 | -10224.5 |
| H2AC19 | -10224.5 |
REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM
| 78 | |
|---|---|
| set | REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM |
| setSize | 688 |
| pANOVA | 3.19e-05 |
| s.dist | 0.093 |
| p.adjustANOVA | 0.00159 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CCL4 | 11130 |
| GH1 | 11086 |
| IL32 | 11052 |
| IFNA13 | 11049 |
| FCER2 | 11028 |
| ELOB | 10991 |
| IFNA1 | 10960 |
| IL12RB1 | 10774 |
| TNFSF8 | 10736 |
| MUC1 | 10668 |
| TNFSF13 | 10569 |
| IL27 | 10526 |
| IL1RL1 | 10513 |
| IRF8 | 10504 |
| HLA-DPA1 | 10437 |
| PTPN11 | 10353 |
| AIP | 10333 |
| PSMD12 | 10325 |
| IFIT2 | 10324 |
| S100B | 10265 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CCL4 | 11130.0 |
| GH1 | 11086.0 |
| IL32 | 11052.0 |
| IFNA13 | 11049.0 |
| FCER2 | 11028.0 |
| ELOB | 10991.0 |
| IFNA1 | 10960.0 |
| IL12RB1 | 10774.0 |
| TNFSF8 | 10736.0 |
| MUC1 | 10668.0 |
| TNFSF13 | 10569.0 |
| IL27 | 10526.0 |
| IL1RL1 | 10513.0 |
| IRF8 | 10504.0 |
| HLA-DPA1 | 10437.0 |
| PTPN11 | 10353.0 |
| AIP | 10333.0 |
| PSMD12 | 10325.0 |
| IFIT2 | 10324.0 |
| S100B | 10265.0 |
| GBP4 | 10230.0 |
| CNTFR | 10175.0 |
| CXCL1 | 10160.0 |
| CXCL2 | 10139.0 |
| OASL | 10086.0 |
| TRIM21 | 10071.0 |
| EIF4A1 | 10017.0 |
| IL21R | 9984.0 |
| TRIM38 | 9981.0 |
| PSMC6 | 9977.0 |
| GSTA2 | 9945.0 |
| JUNB | 9929.0 |
| PSMB3 | 9858.0 |
| IL7 | 9831.0 |
| CCR2 | 9813.0 |
| RNF7 | 9796.0 |
| IFNGR2 | 9768.0 |
| TNFSF4 | 9734.0 |
| IRAK3 | 9647.0 |
| TRIM8 | 9631.0 |
| JUN | 9609.0 |
| TIFA | 9606.0 |
| UBA7 | 9564.0 |
| CXCL8 | 9558.0 |
| CD27 | 9536.0 |
| VAV1 | 9507.0 |
| UBC | 9476.0 |
| STAT3 | 9471.0 |
| UBE2V1 | 9459.0 |
| CD70 | 9445.0 |
| IL12A | 9440.0 |
| LTA | 9431.0 |
| ELOC | 9413.0 |
| IFNLR1 | 9377.0 |
| PIAS1 | 9344.0 |
| DUSP3 | 9307.0 |
| RBX1 | 9293.0 |
| IL4 | 9277.0 |
| PTPN7 | 9253.0 |
| PRTN3 | 9235.0 |
| IL6 | 9220.0 |
| STAT5A | 9217.0 |
| RPLP0 | 9213.0 |
| IFNAR1 | 9173.0 |
| LCK | 9065.0 |
| CD40 | 9038.0 |
| H3C10 | 9015.0 |
| SYK | 8993.0 |
| CSH1 | 8973.0 |
| PTPN2 | 8968.0 |
| H3C11 | 8963.0 |
| TNFRSF1B | 8954.0 |
| POM121 | 8943.0 |
| ISG15 | 8922.0 |
| TNFSF13B | 8797.0 |
| CSK | 8777.0 |
| HLA-G | 8743.0 |
| MAPK14 | 8739.0 |
| CTF1 | 8731.0 |
| PPP2R5D | 8711.0 |
| DUSP4 | 8698.0 |
| PSME2 | 8685.0 |
| LYN | 8661.0 |
| SHC1 | 8640.0 |
| FLT3LG | 8637.0 |
| SH2B3 | 8636.0 |
| IL12B | 8595.0 |
| CIITA | 8566.0 |
| SH2B1 | 8466.0 |
| STAT6 | 8465.0 |
| CDKN1B | 8453.0 |
| TGFB1 | 8436.0 |
| UBA3 | 8341.0 |
| STX3 | 8322.0 |
| TNFRSF12A | 8320.0 |
| CANX | 8307.0 |
| CNTF | 8278.0 |
| FGF2 | 8274.0 |
| TRIM14 | 8238.0 |
| NFKBIB | 8232.0 |
| CCR1 | 8208.0 |
| CCR5 | 8206.0 |
| PSMB4 | 8180.0 |
| DUSP7 | 8174.0 |
| GRB2 | 8138.0 |
| IL10RA | 8136.0 |
| TP53 | 8108.0 |
| PTPN6 | 8069.0 |
| H3C12 | 8052.0 |
| JAK1 | 8034.0 |
| TNFRSF6B | 7921.0 |
| PSMD13 | 7901.0 |
| CD80 | 7894.0 |
| LTB | 7879.0 |
| IL20 | 7857.0 |
| TNFRSF1A | 7783.0 |
| CFL1 | 7777.0 |
| MTAP | 7766.0 |
| NUP155 | 7761.0 |
| VRK3 | 7733.0 |
| PSME4 | 7705.0 |
| MAP2K3 | 7685.0 |
| UBB | 7674.0 |
| IFNGR1 | 7666.0 |
| PSMB2 | 7641.0 |
| P4HB | 7631.0 |
| EIF4G3 | 7603.0 |
| IL18 | 7601.0 |
| EIF4E | 7566.0 |
| IFI30 | 7553.0 |
| GH2 | 7506.0 |
| HSPA8 | 7490.0 |
| VEGFA | 7485.0 |
| TNFSF9 | 7437.0 |
| PSMB11 | 7359.0 |
| PTPN1 | 7323.0 |
| CCL5 | 7315.0 |
| HLA-DRA | 7312.0 |
| IFNA7 | 7302.0 |
| B2M | 7278.0 |
| TCP1 | 7231.0 |
| PSMA6 | 7190.0 |
| BIRC5 | 7158.0 |
| RPS27A | 7120.0 |
| IL7R | 7080.0 |
| STAT2 | 7075.0 |
| LCP1 | 7039.0 |
| MIF | 7025.0 |
| PSMA1 | 7018.0 |
| GBP3 | 7010.0 |
| TRIM46 | 7001.0 |
| STX4 | 6980.0 |
| PIK3R2 | 6906.0 |
| IL16 | 6900.0 |
| SEH1L | 6838.0 |
| NKIRAS2 | 6833.0 |
| NUP35 | 6822.0 |
| PELI3 | 6746.0 |
| CSF2RB | 6711.0 |
| NUP85 | 6688.0 |
| PSMD3 | 6672.0 |
| IFITM2 | 6613.0 |
| EDARADD | 6550.0 |
| MAP2K7 | 6542.0 |
| CD36 | 6523.0 |
| HCK | 6499.0 |
| ABL2 | 6455.0 |
| EIF4A3 | 6420.0 |
| NUP37 | 6306.0 |
| HMGB1 | 6295.0 |
| BCL6 | 6221.0 |
| PTPN12 | 6204.0 |
| IFNA14 | 6151.0 |
| IFI35 | 6131.0 |
| MAP3K14 | 6091.0 |
| IFNA2 | 6068.0 |
| CREB1 | 6047.0 |
| BCL2 | 5940.0 |
| IL17RE | 5936.0 |
| OSM | 5926.0 |
| ARIH1 | 5925.0 |
| NUP43 | 5921.0 |
| IFNAR2 | 5911.0 |
| STXBP2 | 5859.0 |
| GRAP2 | 5829.0 |
| PSMC1 | 5715.0 |
| IRAK2 | 5710.0 |
| IFIT3 | 5656.0 |
| IRF3 | 5649.0 |
| NUP54 | 5644.0 |
| PSMD2 | 5624.0 |
| STAT5B | 5614.0 |
| H3C1 | 5598.0 |
| HLA-DRB1 | 5595.0 |
| INPP5D | 5593.0 |
| HLA-DQB1 | 5584.0 |
| GBP7 | 5555.0 |
| IL22RA2 | 5506.0 |
| CHUK | 5500.0 |
| BCL2L1 | 5479.0 |
| NFKBIA | 5436.0 |
| IL17C | 5420.0 |
| IRAK4 | 5412.0 |
| IFNA8 | 5410.0 |
| HLA-E | 5384.0 |
| ITGAM | 5378.0 |
| CAPZA1 | 5374.0 |
| CEBPD | 5373.0 |
| IFNA16 | 5367.0 |
| PSMA5 | 5362.0 |
| PSMA4 | 5246.0 |
| PTK2B | 5226.0 |
| PSMC5 | 5193.0 |
| TRIM68 | 5124.0 |
| NUP107 | 5069.0 |
| CDKN1A | 5054.0 |
| CUL5 | 5014.0 |
| SMAD7 | 4978.0 |
| ABCE1 | 4911.0 |
| SLA | 4907.0 |
| BLNK | 4880.0 |
| TNFRSF11A | 4824.0 |
| KRAS | 4814.0 |
| VAMP2 | 4802.0 |
| NUP88 | 4788.0 |
| IL27RA | 4767.0 |
| PIK3CG | 4763.0 |
| DUSP6 | 4740.0 |
| FN1 | 4719.0 |
| H3C4 | 4718.0 |
| IL2RB | 4692.0 |
| SNAP25 | 4681.0 |
| NUP133 | 4676.0 |
| YWHAZ | 4655.0 |
| IL9 | 4638.0 |
| BATF | 4593.0 |
| PTPRJ | 4578.0 |
| IL1RAP | 4530.0 |
| VIM | 4494.0 |
| RPS6KA1 | 4484.0 |
| FYN | 4444.0 |
| IL18RAP | 4396.0 |
| IRF4 | 4386.0 |
| KPNB1 | 4376.0 |
| ITGB2 | 4336.0 |
| TSLP | 4325.0 |
| MAP3K8 | 4314.0 |
| PSMF1 | 4311.0 |
| RAPGEF1 | 4300.0 |
| SOCS1 | 4294.0 |
| IRF1 | 4240.0 |
| PSMD1 | 4227.0 |
| APP | 4173.0 |
| PSME3 | 4172.0 |
| PTPN18 | 4166.0 |
| MAPKAPK2 | 4162.0 |
| IRF9 | 4154.0 |
| GATA3 | 4111.0 |
| PSMC2 | 4088.0 |
| TNFSF12 | 4045.0 |
| FASLG | 3973.0 |
| PSMA8 | 3923.0 |
| PSMA7 | 3903.0 |
| HLA-DQB2 | 3881.0 |
| PSME1 | 3866.0 |
| HNRNPA2B1 | 3853.0 |
| PSMA3 | 3850.0 |
| TRIM45 | 3814.0 |
| HERC5 | 3783.0 |
| NUP205 | 3738.0 |
| TWIST1 | 3725.0 |
| CDC42 | 3714.0 |
| IL24 | 3694.0 |
| KPNA2 | 3680.0 |
| UBE2D2 | 3677.0 |
| HIF1A | 3657.0 |
| ATF2 | 3606.0 |
| TEC | 3601.0 |
| SOS1 | 3578.0 |
| IL10RB | 3540.0 |
| SKP1 | 3534.0 |
| PRKACA | 3519.0 |
| CSF3R | 3484.0 |
| ZEB1 | 3464.0 |
| PSMB9 | 3459.0 |
| MAPK9 | 3453.0 |
| KPNA1 | 3308.0 |
| KPNA7 | 3260.0 |
| EIF4A2 | 3184.0 |
| CTSG | 3167.0 |
| PITPNA | 3166.0 |
| TRIM2 | 3144.0 |
| CASP8 | 3129.0 |
| IL34 | 3089.0 |
| PIK3CD | 3030.0 |
| H3C6 | 3009.0 |
| PSMC4 | 3004.0 |
| UBE2D3 | 2976.0 |
| PSMC3 | 2960.0 |
| ALOX15 | 2952.0 |
| NUP42 | 2844.0 |
| EIF4E3 | 2824.0 |
| RSAD2 | 2805.0 |
| IRF6 | 2801.0 |
| NUP93 | 2792.0 |
| MAP2K1 | 2768.0 |
| RELB | 2738.0 |
| NUP58 | 2703.0 |
| H3C8 | 2699.0 |
| IL13 | 2664.0 |
| RANBP2 | 2651.0 |
| COL1A2 | 2619.0 |
| HLA-DQA1 | 2586.0 |
| TOLLIP | 2585.0 |
| TAB1 | 2578.0 |
| TNFRSF9 | 2531.0 |
| SEM1 | 2517.0 |
| POMC | 2478.0 |
| TRIM26 | 2442.0 |
| PAK2 | 2407.0 |
| IRF5 | 2363.0 |
| TNFRSF8 | 2356.0 |
| OAS3 | 2355.0 |
| UBE2N | 2342.0 |
| MEF2C | 2335.0 |
| HAVCR2 | 2333.0 |
| TNIP2 | 2319.0 |
| PPP2CA | 2292.0 |
| PIK3CB | 2284.0 |
| FOS | 2247.0 |
| MYD88 | 2230.0 |
| MCL1 | 2209.0 |
| KPNA5 | 2155.0 |
| TNFRSF11B | 2119.0 |
| CCL3 | 2111.0 |
| GAB2 | 2042.0 |
| OAS2 | 1995.0 |
| TRIM5 | 1980.0 |
| IP6K2 | 1969.0 |
| AGER | 1968.0 |
| SOD1 | 1946.0 |
| TRIM6 | 1929.0 |
| IKBIP | 1872.0 |
| MAPKAPK3 | 1801.0 |
| NLRC5 | 1742.0 |
| GSTO1 | 1739.0 |
| BRWD1 | 1617.0 |
| IL1A | 1611.0 |
| EIF4G1 | 1551.0 |
| PIK3CA | 1515.0 |
| IFITM3 | 1506.0 |
| SP100 | 1496.0 |
| H3C2 | 1438.0 |
| HLA-H | 1416.0 |
| SOCS5 | 1356.0 |
| HSP90AA1 | 1355.0 |
| EIF2AK2 | 1335.0 |
| TBK1 | 1331.0 |
| POU2F1 | 1312.0 |
| IL33 | 1279.0 |
| EBI3 | 1236.0 |
| STX1A | 1212.0 |
| VCAM1 | 1169.0 |
| PIK3R1 | 1134.0 |
| STAT1 | 1103.0 |
| ADAR | 1076.0 |
| MX1 | 1060.0 |
| LRRC14 | 1044.0 |
| PML | 1014.0 |
| LBP | 965.0 |
| PIM1 | 940.0 |
| IRF2 | 831.0 |
| SIGIRR | 821.0 |
| EIF4E2 | 738.0 |
| CBL | 728.0 |
| TALDO1 | 727.0 |
| IKBKB | 710.0 |
| PSMD11 | 620.0 |
| PIN1 | 606.0 |
| SQSTM1 | 569.0 |
| IL12RB2 | 526.0 |
| TRIM25 | 479.0 |
| IL6R | 467.0 |
| PSMB8 | 447.0 |
| ANXA1 | 436.0 |
| SOCS6 | 362.0 |
| HSP90B1 | 354.0 |
| SMARCA4 | 311.0 |
| IL10 | 269.0 |
| CLCF1 | 222.0 |
| BTRC | 216.0 |
| CRLF1 | 193.0 |
| BCL2L11 | 135.0 |
| TNFSF18 | 134.0 |
| TXLNA | 27.0 |
| PSMA2 | -85.0 |
| CAMK2B | -127.0 |
| NKIRAS1 | -185.0 |
| NEDD4 | -236.0 |
| SNRPA1 | -241.0 |
| PTPN13 | -252.0 |
| FSCN1 | -286.0 |
| TRIM10 | -293.0 |
| NUP98 | -351.0 |
| SLA2 | -404.0 |
| STAT4 | -414.0 |
| NOS2 | -416.0 |
| UBE2M | -450.0 |
| SAMHD1 | -453.0 |
| NOD1 | -481.0 |
| H3C3 | -546.0 |
| YES1 | -652.0 |
| MEF2A | -686.0 |
| FOXO1 | -711.0 |
| MAPK1 | -857.0 |
| PSMD14 | -865.0 |
| PDCD4 | -916.0 |
| PSMD6 | -961.0 |
| CCND1 | -962.0 |
| FBXW11 | -964.0 |
| TNFRSF13B | -970.0 |
| PIK3R3 | -980.0 |
| EIF4G2 | -991.0 |
| CD86 | -1023.0 |
| IL6ST | -1046.0 |
| NFKB2 | -1089.0 |
| PTPN5 | -1097.0 |
| PTPN23 | -1135.0 |
| MAP3K3 | -1136.0 |
| MMP9 | -1149.0 |
| PPIA | -1195.0 |
| IRS1 | -1205.0 |
| TRIM31 | -1222.0 |
| IL1F10 | -1249.0 |
| NRAS | -1287.0 |
| PSMB7 | -1294.0 |
| KPNA4 | -1299.0 |
| ALPK1 | -1313.0 |
| LMNB1 | -1316.0 |
| MAPK7 | -1357.0 |
| FLNB | -1393.0 |
| IL4R | -1409.0 |
| NDC1 | -1433.0 |
| IL17A | -1556.0 |
| IL17F | -1612.0 |
| NOD2 | -1614.0 |
| ARF1 | -1636.0 |
| IL5RA | -1640.0 |
| HRAS | -1663.0 |
| MAP3K7 | -1717.0 |
| HNRNPF | -1749.0 |
| CD44 | -1755.0 |
| RPS6KA5 | -1764.0 |
| RIPK2 | -1779.0 |
| NLRX1 | -1784.0 |
| CASP3 | -1837.0 |
| IL17RC | -1851.0 |
| NUP188 | -1877.0 |
| ISG20 | -1883.0 |
| SOS2 | -1920.0 |
| MMP2 | -1984.0 |
| ADAM17 | -1988.0 |
| MAP2K4 | -2008.0 |
| TRAF3 | -2012.0 |
| MAP2K6 | -2038.0 |
| IL17RB | -2057.0 |
| S1PR1 | -2060.0 |
| HLA-DQA2 | -2099.0 |
| PPP2R1A | -2107.0 |
| IL2 | -2134.0 |
| F13A1 | -2143.0 |
| CISH | -2201.0 |
| MAPK11 | -2236.0 |
| THOC5 | -2259.0 |
| PSMB10 | -2290.0 |
| LIFR | -2307.0 |
| PSMB6 | -2408.0 |
| JAK2 | -2410.0 |
| CUL1 | -2437.0 |
| SOCS2 | -2445.0 |
| AKT2 | -2480.0 |
| SUMO1 | -2534.0 |
| RAP1B | -2541.0 |
| AKT1 | -2548.0 |
| IL36B | -2559.0 |
| PSMD9 | -2570.0 |
| MYC | -2593.0 |
| CCL2 | -2609.0 |
| N4BP1 | -2646.0 |
| UBE2E1 | -2647.0 |
| IL2RA | -2662.0 |
| USP18 | -2665.0 |
| TRIM62 | -2675.0 |
| AAAS | -2839.0 |
| RPS6KA2 | -2842.0 |
| NANOG | -2938.0 |
| RORA | -2965.0 |
| IL31RA | -2979.0 |
| OSMR | -3162.0 |
| RHOU | -3180.0 |
| RIGI | -3256.0 |
| MAPK10 | -3279.0 |
| HLA-B | -3298.0 |
| PTAFR | -3334.0 |
| GRB10 | -3358.0 |
| TNFRSF18 | -3412.0 |
| NUP153 | -3416.0 |
| HSPA9 | -3436.0 |
| IL1RL2 | -3475.0 |
| HGF | -3482.0 |
| RAE1 | -3503.0 |
| IFI27 | -3591.0 |
| IFNB1 | -3599.0 |
| UBA52 | -3755.0 |
| BIRC3 | -3823.0 |
| ALOX5 | -3865.0 |
| IL22RA1 | -3866.0 |
| OPRD1 | -3929.0 |
| TRIM3 | -3974.0 |
| CAMK2D | -3981.0 |
| POM121C | -4045.0 |
| IL11RA | -4064.0 |
| MMP3 | -4091.0 |
| SOX2 | -4140.0 |
| SRC | -4161.0 |
| IL20RA | -4171.0 |
| SMAD3 | -4228.0 |
| IL31 | -4388.0 |
| PELI1 | -4405.0 |
| PLCG2 | -4486.0 |
| IL19 | -4545.0 |
| HLA-DPB1 | -4581.0 |
| ATF1 | -4593.0 |
| PRLR | -4639.0 |
| PTPN9 | -4640.0 |
| PDE12 | -4670.0 |
| PSMB5 | -4687.0 |
| PRL | -4706.0 |
| IL1R2 | -4764.0 |
| H3C7 | -4907.5 |
| ITGAX | -4914.0 |
| OPRM1 | -4973.0 |
| IRS2 | -5060.0 |
| CSF1R | -5061.0 |
| PELI2 | -5066.0 |
| HMOX1 | -5069.0 |
| LAMA5 | -5130.0 |
| PSMD7 | -5198.0 |
| IFIT5 | -5221.0 |
| FOXO3 | -5268.0 |
| ICAM1 | -5275.0 |
| KPNA3 | -5285.0 |
| HLA-DRB5 | -5334.0 |
| PSMD4 | -5337.0 |
| RAG2 | -5350.0 |
| UBE2D1 | -5394.0 |
| PRKCD | -5412.0 |
| FPR1 | -5421.0 |
| MAPK3 | -5444.0 |
| NUP214 | -5472.0 |
| FLT3 | -5572.0 |
| PPM1B | -5577.0 |
| AKT3 | -5586.0 |
| TRIM17 | -5616.0 |
| TNFSF15 | -5628.0 |
| SEC13 | -5670.0 |
| ANXA2 | -5678.0 |
| BST2 | -5683.0 |
| JAK3 | -5722.0 |
| HLA-C | -5724.0 |
| TNFRSF17 | -5776.0 |
| CCL19 | -5815.0 |
| TAB2 | -5833.0 |
| EGR1 | -5847.0 |
| PSMB1 | -5858.0 |
| OAS1 | -5920.0 |
| PTGS2 | -5921.0 |
| IL36A | -5997.0 |
| CAMK2G | -6002.0 |
| IL1R1 | -6039.0 |
| LCN2 | -6073.0 |
| GHR | -6098.0 |
| PTPN14 | -6101.0 |
| IL5 | -6108.0 |
| TNF | -6126.0 |
| NUP50 | -6183.0 |
| CRKL | -6194.0 |
| NCAM1 | -6219.0 |
| TRAF6 | -6221.0 |
| TRIM35 | -6278.0 |
| IL1B | -6400.0 |
| LTBR | -6480.0 |
| PTPRZ1 | -6498.0 |
| RNASEL | -6537.0 |
| TNFRSF25 | -6548.0 |
| CAMK2A | -6562.0 |
| NUP210 | -6637.0 |
| RORC | -6673.0 |
| UBE2L6 | -6675.0 |
| USP14 | -6682.0 |
| IL1RN | -6702.0 |
| HNRNPDL | -6811.0 |
| IL23R | -6812.0 |
| IL20RB | -6844.0 |
| IL37 | -6886.0 |
| GBP1 | -6915.0 |
| IL22 | -7019.0 |
| TNFRSF13C | -7051.0 |
| MX2 | -7109.0 |
| NUP160 | -7169.0 |
| PPP2CB | -7216.0 |
| NUP62 | -7266.0 |
| NFKB1 | -7273.0 |
| SDC1 | -7406.0 |
| IL15 | -7422.0 |
| IL17RA | -7446.0 |
| SOD2 | -7470.0 |
| INPPL1 | -7497.0 |
| CCL20 | -7571.0 |
| GSDMD | -7575.0 |
| CRK | -7608.0 |
| EDAR | -7651.0 |
| CNN2 | -7683.0 |
| MMP1 | -7688.0 |
| IL26 | -7699.0 |
| PSMD8 | -7723.0 |
| BIRC2 | -7754.0 |
| PLCG1 | -7786.0 |
| TYK2 | -7870.0 |
| IL36G | -7905.0 |
| CSF1 | -7916.0 |
| IL15RA | -8032.0 |
| IL25 | -8035.0 |
| RELA | -8093.0 |
| TRAF2 | -8123.0 |
| IL11 | -8177.0 |
| RAG1 | -8213.0 |
| PPP2R1B | -8245.0 |
| SOCS3 | -8251.0 |
| CA1 | -8261.0 |
| PTPN4 | -8273.0 |
| GBP2 | -8292.0 |
| CSF2 | -8316.0 |
| ITGB1 | -8326.0 |
| RALA | -8348.0 |
| CSF3 | -8388.0 |
| IFI6 | -8410.0 |
| MAPK8 | -8692.0 |
| IL18BP | -8696.0 |
| GBP6 | -8757.0 |
| HLA-A | -8825.0 |
| CCL11 | -8831.0 |
| SERPINB2 | -8922.0 |
| IL23A | -8930.0 |
| SAA1 | -8998.0 |
| IL21 | -9004.0 |
| TPR | -9043.0 |
| TRIM22 | -9093.0 |
| TRIM34 | -9100.0 |
| LIF | -9173.0 |
| CASP1 | -9200.0 |
| MT2A | -9208.0 |
| HLA-F | -9277.0 |
| IL36RN | -9401.0 |
| XAF1 | -9413.0 |
| IRF7 | -9417.0 |
| CCL22 | -9480.0 |
| PSMD5 | -9524.0 |
| CD4 | -9562.0 |
| TNFSF11 | -9612.0 |
| IFIT1 | -9704.0 |
| IL18R1 | -9734.0 |
| IFNG | -9825.0 |
| IL3 | -9827.0 |
| CXCL10 | -9843.0 |
| IFNA6 | -9855.0 |
| TNFSF14 | -9889.0 |
| NDN | -9964.0 |
| GBP5 | -10021.0 |
| TRIM29 | -10022.0 |
| TNFRSF4 | -10332.0 |
| IFNL1 | -10367.0 |
| S100A12 | -10430.0 |
| IFNA5 | -10479.0 |
| LGALS9 | -10639.0 |
| IFITM1 | -10743.0 |
| IFNL2 | -10837.0 |
| IFNA21 | -10852.0 |
REACTOME_INFLUENZA_INFECTION
| 228 | |
|---|---|
| set | REACTOME_INFLUENZA_INFECTION |
| setSize | 149 |
| pANOVA | 3.33e-05 |
| s.dist | 0.197 |
| p.adjustANOVA | 0.00161 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| POLR2K | 10402.0 |
| RPL14 | 10215.0 |
| RPL18 | 10082.0 |
| RPL10A | 10035.0 |
| RPL23A | 9830.0 |
| RPS13 | 9737.0 |
| RPL38 | 9474.0 |
| RPS21 | 9255.0 |
| RPLP0 | 9213.0 |
| RPL29 | 9165.0 |
| RPS3A | 8946.0 |
| POM121 | 8943.0 |
| ISG15 | 8922.0 |
| RPL28 | 8875.0 |
| RPL36AL | 8459.5 |
| RPL22L1 | 8449.0 |
| TGFB1 | 8436.0 |
| CANX | 8307.0 |
| RPL31 | 8273.0 |
| PARP1 | 8191.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| POLR2K | 10402.0 |
| RPL14 | 10215.0 |
| RPL18 | 10082.0 |
| RPL10A | 10035.0 |
| RPL23A | 9830.0 |
| RPS13 | 9737.0 |
| RPL38 | 9474.0 |
| RPS21 | 9255.0 |
| RPLP0 | 9213.0 |
| RPL29 | 9165.0 |
| RPS3A | 8946.0 |
| POM121 | 8943.0 |
| ISG15 | 8922.0 |
| RPL28 | 8875.0 |
| RPL36AL | 8459.5 |
| RPL22L1 | 8449.0 |
| TGFB1 | 8436.0 |
| CANX | 8307.0 |
| RPL31 | 8273.0 |
| PARP1 | 8191.0 |
| RPS24 | 8170.0 |
| RPS23 | 8094.0 |
| RPL26 | 8016.0 |
| POLR2I | 7943.0 |
| RPS20 | 7907.0 |
| NUP155 | 7761.0 |
| RPS29 | 7621.0 |
| RPL34 | 7423.0 |
| RPS19 | 7419.0 |
| RPS3 | 7411.0 |
| RPL41 | 7335.0 |
| RPL6 | 7304.0 |
| RPS27A | 7120.0 |
| CALR | 6943.0 |
| RPL23 | 6935.0 |
| SEH1L | 6838.0 |
| NUP35 | 6822.0 |
| NUP85 | 6688.0 |
| FAU | 6424.0 |
| RPL11 | 6414.0 |
| RPL21 | 6341.0 |
| NUP37 | 6306.0 |
| RPL13 | 6125.0 |
| RPS26 | 6058.0 |
| RPL7A | 5991.0 |
| NUP43 | 5921.0 |
| RPS16 | 5896.0 |
| RPL8 | 5822.0 |
| RPS7 | 5716.0 |
| RAN | 5697.0 |
| NUP54 | 5644.0 |
| RPL26L1 | 5531.0 |
| PABPN1 | 5490.0 |
| RPS8 | 5431.0 |
| CLTC | 5328.0 |
| RPL37A | 5292.0 |
| RPL3L | 5206.0 |
| RPL13A | 5131.5 |
| NUP107 | 5069.0 |
| RPS10 | 5058.0 |
| RPL19 | 4913.0 |
| RPS18 | 4856.0 |
| NUP88 | 4788.0 |
| RPL9 | 4760.0 |
| RPS27 | 4711.0 |
| NUP133 | 4676.0 |
| RPS12 | 4501.0 |
| RPL35 | 4434.0 |
| KPNB1 | 4376.0 |
| RPL35A | 4218.0 |
| RPL17 | 4202.0 |
| POLR2A | 3916.0 |
| NUP205 | 3738.0 |
| KPNA2 | 3680.0 |
| KPNA1 | 3308.0 |
| RPSA | 3281.0 |
| KPNA7 | 3260.0 |
| RPL3 | 3240.0 |
| POLR2E | 3177.0 |
| GTF2F2 | 2945.0 |
| NUP42 | 2844.0 |
| RPL12 | 2822.0 |
| NUP93 | 2792.0 |
| NUP58 | 2703.0 |
| RPS28 | 2669.0 |
| RANBP2 | 2651.0 |
| RPL27A | 2494.0 |
| RPL15 | 2382.0 |
| RPL32 | 2362.0 |
| KPNA5 | 2155.0 |
| RPS15A | 2095.0 |
| DNAJC3 | 2083.0 |
| POLR2D | 2025.0 |
| RPS25 | 1988.0 |
| RPLP1 | 1762.0 |
| RPL7 | 1442.0 |
| HSP90AA1 | 1355.0 |
| EIF2AK2 | 1335.0 |
| IPO5 | -110.0 |
| RPL5 | -139.0 |
| NUP98 | -351.0 |
| GRSF1 | -941.0 |
| POLR2L | -971.0 |
| RPS2 | -1028.0 |
| XPO1 | -1083.0 |
| KPNA4 | -1299.0 |
| NDC1 | -1433.0 |
| RPS14 | -1691.0 |
| NUP188 | -1877.0 |
| RPL30 | -2061.0 |
| RPS5 | -2579.0 |
| RPS6 | -2673.0 |
| AAAS | -2839.0 |
| RPL39L | -3132.0 |
| POLR2B | -3234.0 |
| RPL37 | -3282.0 |
| NUP153 | -3416.0 |
| RAE1 | -3503.0 |
| UBA52 | -3755.0 |
| CPSF4 | -3838.0 |
| POM121C | -4045.0 |
| RPS15 | -4150.0 |
| CLTA | -4284.0 |
| GTF2F1 | -4505.0 |
| RPL24 | -4644.0 |
| RPS9 | -4650.0 |
| POLR2F | -4762.0 |
| RPL4 | -5128.0 |
| KPNA3 | -5285.0 |
| RPL27 | -5306.0 |
| RPL18A | -5425.0 |
| POLR2C | -5430.0 |
| NUP214 | -5472.0 |
| SEC13 | -5670.0 |
| RPL22 | -5765.0 |
| RPLP2 | -5777.0 |
| RPS27L | -5945.0 |
| POLR2J | -6011.0 |
| NUP50 | -6183.0 |
| POLR2H | -6261.0 |
| HSPA1A | -6507.0 |
| NUP210 | -6637.0 |
| NUP160 | -7169.0 |
| NUP62 | -7266.0 |
| RPL36 | -8155.0 |
| POLR2G | -8279.0 |
| RPS11 | -8626.0 |
| TPR | -9043.0 |
| RPL10L | -10090.0 |
REACTOME_PROTEIN_LOCALIZATION
| 1461 | |
|---|---|
| set | REACTOME_PROTEIN_LOCALIZATION |
| setSize | 153 |
| pANOVA | 5.19e-05 |
| s.dist | 0.19 |
| p.adjustANOVA | 0.00243 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| DHRS4 | 10666 |
| ECH1 | 10485 |
| SEC61B | 10362 |
| COQ2 | 10258 |
| ATP5F1B | 10114 |
| HMGCL | 10105 |
| GSTK1 | 9827 |
| CHCHD2 | 9512 |
| UBC | 9476 |
| PAM16 | 9349 |
| PEX12 | 9176 |
| ACOT4 | 9047 |
| GET3 | 9043 |
| HAO2 | 9029 |
| MLYCD | 8832 |
| PXMP4 | 8820 |
| PEX6 | 8745 |
| MTX1 | 8540 |
| TIMM23 | 8537 |
| HAO1 | 8464 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| DHRS4 | 10666 |
| ECH1 | 10485 |
| SEC61B | 10362 |
| COQ2 | 10258 |
| ATP5F1B | 10114 |
| HMGCL | 10105 |
| GSTK1 | 9827 |
| CHCHD2 | 9512 |
| UBC | 9476 |
| PAM16 | 9349 |
| PEX12 | 9176 |
| ACOT4 | 9047 |
| GET3 | 9043 |
| HAO2 | 9029 |
| MLYCD | 8832 |
| PXMP4 | 8820 |
| PEX6 | 8745 |
| MTX1 | 8540 |
| TIMM23 | 8537 |
| HAO1 | 8464 |
| HACL1 | 8415 |
| CS | 8368 |
| ACOT8 | 8162 |
| TOMM6 | 8146 |
| PEX2 | 8021 |
| TOMM20 | 7924 |
| NUDT19 | 7824 |
| IDE | 7794 |
| PEX13 | 7745 |
| UBB | 7674 |
| STX5 | 7376 |
| PIPOX | 7172 |
| TOMM40 | 7136 |
| TIMM9 | 7128 |
| RPS27A | 7120 |
| SLC25A4 | 7067 |
| TOMM70 | 6987 |
| TOMM5 | 6916 |
| CRAT | 6730 |
| SAMM50 | 6609 |
| NUDT7 | 6602 |
| PAOX | 6589 |
| ACOX1 | 6543 |
| ECI2 | 6533 |
| CHCHD5 | 6469 |
| ATP5MC1 | 6467 |
| BAAT | 6402 |
| PEX11B | 6378 |
| FIS1 | 6240 |
| ACOT2 | 6239 |
| ABCD3 | 6159 |
| HSCB | 5961 |
| SLC25A13 | 5799 |
| SCP2 | 5725 |
| ATP5F1A | 5722 |
| PEX16 | 5575 |
| COA4 | 5418 |
| COX17 | 5364 |
| GRPEL1 | 5341 |
| TIMM8B | 5159 |
| SEC61G | 5145 |
| NDUFB8 | 4967 |
| IDH1 | 4950 |
| PEX5 | 4944 |
| BCS1L | 4923 |
| VAMP2 | 4802 |
| TOMM22 | 4675 |
| PEX10 | 4236 |
| APP | 4173 |
| BAG6 | 3882 |
| EHHADH | 3858 |
| CHCHD4 | 3849 |
| GET1 | 3679 |
| UBE2D2 | 3677 |
| PHYH | 3490 |
| HSD17B4 | 3290 |
| MPV17 | 3176 |
| UBE2D3 | 2976 |
| CYB5A | 2662 |
| TIMM50 | 2565 |
| PMPCB | 2554 |
| CMC2 | 2508 |
| PEX19 | 2487 |
| PEX3 | 2436 |
| DECR2 | 2367 |
| SGTA | 2235 |
| PITRM1 | 2154 |
| CROT | 2152 |
| GFER | 2057 |
| GNPAT | 1970 |
| ATAD1 | 1852 |
| PEX7 | 1735 |
| PXMP2 | 1563 |
| TIMM10B | 1530 |
| PEX26 | 1489 |
| COA6 | 1487 |
| EPHX2 | 1272 |
| STX1A | 1212 |
| TIMM17A | 1156 |
| GET4 | 982 |
| SERP1 | 898 |
| PEX1 | 693 |
| TIMM13 | -60 |
| TOMM7 | -142 |
| NOS2 | -416 |
| SLC25A17 | -534 |
| DNAJC19 | -808 |
| ABCD2 | -871 |
| CAT | -1504 |
| CHCHD10 | -1652 |
| AGPS | -1711 |
| CHCHD7 | -1871 |
| CYC1 | -1925 |
| ACOX3 | -2085 |
| AMACR | -2550 |
| DAO | -2721 |
| OTOF | -2806 |
| PEX14 | -3153 |
| TIMM44 | -3176 |
| HSPA9 | -3436 |
| PMPCA | -3536 |
| GRPEL2 | -3573 |
| UBA52 | -3755 |
| ACAA1 | -3917 |
| FXN | -4157 |
| LDHD | -4159 |
| LONP2 | -4160 |
| VAPA | -4193 |
| ZFAND6 | -4797 |
| HMOX1 | -5069 |
| COX19 | -5160 |
| PECR | -5329 |
| UBE2D1 | -5394 |
| PRNP | -6230 |
| ALDH3A2 | -6300 |
| CHCHD3 | -6358 |
| GDAP1 | -6432 |
| TIMM22 | -6457 |
| HSPD1 | -6508 |
| TIMM10 | -6631 |
| TYSND1 | -7009 |
| DDO | -7110 |
| UBE2J2 | -7332 |
| ACBD5 | -7397 |
| ACO2 | -7475 |
| CAMLG | -7903 |
| TIMM21 | -7953 |
| SLC25A12 | -7958 |
| SLC27A2 | -8217 |
| MTX2 | -8385 |
| ACOX2 | -8938 |
| VDAC1 | -9609 |
| AGXT | -10379 |
REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS
| 810 | |
|---|---|
| set | REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS |
| setSize | 86 |
| pANOVA | 0.000105 |
| s.dist | 0.242 |
| p.adjustANOVA | 0.00478 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TNFSF13 | 10569 |
| PSMD12 | 10325 |
| ZFP36 | 10115 |
| PSMC6 | 9977 |
| EXOSC5 | 9863 |
| PSMB3 | 9858 |
| UBC | 9476 |
| HSPB1 | 9467 |
| EXOSC1 | 9393 |
| KHSRP | 8781 |
| MAPK14 | 8739 |
| ZFP36L1 | 8715 |
| PSME2 | 8685 |
| PABPC1 | 8543 |
| PSMB4 | 8180 |
| EXOSC9 | 7985 |
| PSMD13 | 7901 |
| PSME4 | 7705 |
| UBB | 7674 |
| PSMB2 | 7641 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TNFSF13 | 10569 |
| PSMD12 | 10325 |
| ZFP36 | 10115 |
| PSMC6 | 9977 |
| EXOSC5 | 9863 |
| PSMB3 | 9858 |
| UBC | 9476 |
| HSPB1 | 9467 |
| EXOSC1 | 9393 |
| KHSRP | 8781 |
| MAPK14 | 8739 |
| ZFP36L1 | 8715 |
| PSME2 | 8685 |
| PABPC1 | 8543 |
| PSMB4 | 8180 |
| EXOSC9 | 7985 |
| PSMD13 | 7901 |
| PSME4 | 7705 |
| UBB | 7674 |
| PSMB2 | 7641 |
| DIS3 | 7503 |
| HSPA8 | 7490 |
| PSMB11 | 7359 |
| PSMA6 | 7190 |
| RPS27A | 7120 |
| PSMA1 | 7018 |
| EXOSC4 | 6868 |
| ANP32A | 6719 |
| PSMD3 | 6672 |
| YWHAB | 5879 |
| PSMC1 | 5715 |
| PSMD2 | 5624 |
| PSMA5 | 5362 |
| PSMA4 | 5246 |
| PSMC5 | 5193 |
| YWHAZ | 4655 |
| PSMF1 | 4311 |
| EXOSC3 | 4242 |
| PSMD1 | 4227 |
| PSME3 | 4172 |
| MAPKAPK2 | 4162 |
| PSMC2 | 4088 |
| TNPO1 | 4083 |
| PSMA8 | 3923 |
| PSMA7 | 3903 |
| PSME1 | 3866 |
| PSMA3 | 3850 |
| PSMB9 | 3459 |
| SET | 3096 |
| EXOSC7 | 3025 |
| PSMC4 | 3004 |
| PSMC3 | 2960 |
| PARN | 2863 |
| HNRNPD | 2711 |
| SEM1 | 2517 |
| EIF4G1 | 1551 |
| PSMD11 | 620 |
| PSMB8 | 447 |
| PSMA2 | -85 |
| EXOSC8 | -119 |
| PSMD14 | -865 |
| PSMD6 | -961 |
| XPO1 | -1083 |
| PSMB7 | -1294 |
| EXOSC6 | -1460 |
| MAPK11 | -2236 |
| PSMB10 | -2290 |
| PSMB6 | -2408 |
| AKT1 | -2548 |
| PSMD9 | -2570 |
| PRKCA | -3175 |
| DCP2 | -3374 |
| UBA52 | -3755 |
| PSMB5 | -4687 |
| ELAVL1 | -5092 |
| PSMD7 | -5198 |
| PSMD4 | -5337 |
| PRKCD | -5412 |
| NUP214 | -5472 |
| PSMB1 | -5858 |
| HSPA1A | -6507 |
| EXOSC2 | -6711 |
| DCP1A | -7071 |
| PSMD8 | -7723 |
| XRN1 | -9024 |
| PSMD5 | -9524 |
REACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE
| 501 | |
|---|---|
| set | REACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE |
| setSize | 118 |
| pANOVA | 0.00015 |
| s.dist | 0.202 |
| p.adjustANOVA | 0.00667 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| E2F1 | 10764 |
| CDKN2D | 10762 |
| H4C8 | 10752 |
| CDK4 | 10506 |
| CDKN2B | 10314 |
| AGO1 | 10212 |
| SUZ12 | 10134 |
| H2AJ | 9870 |
| JUN | 9609 |
| UBC | 9476 |
| MIR24-2 | 9434 |
| H3C10 | 9015 |
| TXN | 8969 |
| H3C11 | 8963 |
| H4C12 | 8883 |
| MAPK14 | 8739 |
| H4C2 | 8690 |
| H3-3A | 8639 |
| H2BC13 | 8609 |
| MDM4 | 8496 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| E2F1 | 10764.0 |
| CDKN2D | 10762.0 |
| H4C8 | 10752.0 |
| CDK4 | 10506.0 |
| CDKN2B | 10314.0 |
| AGO1 | 10212.0 |
| SUZ12 | 10134.0 |
| H2AJ | 9870.0 |
| JUN | 9609.0 |
| UBC | 9476.0 |
| MIR24-2 | 9434.0 |
| H3C10 | 9015.0 |
| TXN | 8969.0 |
| H3C11 | 8963.0 |
| H4C12 | 8883.0 |
| MAPK14 | 8739.0 |
| H4C2 | 8690.0 |
| H3-3A | 8639.0 |
| H2BC13 | 8609.0 |
| MDM4 | 8496.0 |
| H2BC1 | 8383.0 |
| TP53 | 8108.0 |
| H3C12 | 8052.0 |
| H2AZ2 | 7814.0 |
| H2AC7 | 7754.5 |
| H2BC7 | 7754.5 |
| MAP2K3 | 7685.0 |
| UBB | 7674.0 |
| CDKN2A | 7282.0 |
| H4C16 | 7260.0 |
| RPS27A | 7120.0 |
| KDM6B | 7004.0 |
| RBBP4 | 6844.0 |
| H2AC8 | 6630.0 |
| MAP2K7 | 6542.0 |
| MOV10 | 6170.0 |
| H3-3B | 6110.0 |
| H2BC8 | 6087.0 |
| H4C3 | 5935.0 |
| H4C1 | 5864.0 |
| H3C1 | 5598.0 |
| AGO4 | 5459.0 |
| PHC1 | 5291.0 |
| H2BC5 | 5130.0 |
| H4C6 | 4952.0 |
| H3C4 | 4718.0 |
| BMI1 | 4673.0 |
| H2BC3 | 4658.0 |
| H4C13 | 4630.0 |
| H4C11 | 4553.0 |
| MAP3K5 | 4207.0 |
| TNRC6B | 4201.0 |
| MAPKAPK2 | 4162.0 |
| H2BC10 | 3947.0 |
| H4C4 | 3785.0 |
| CBX2 | 3753.0 |
| MAPK9 | 3453.0 |
| CDKN2C | 3429.0 |
| TFDP2 | 3339.0 |
| H2BC17 | 3276.0 |
| H3C6 | 3009.0 |
| H2AC6 | 2946.0 |
| H3C8 | 2699.0 |
| CBX6 | 2581.0 |
| H2AC4 | 2379.0 |
| FOS | 2247.0 |
| MAPKAPK5 | 2167.0 |
| TNIK | 1815.0 |
| MAPKAPK3 | 1801.0 |
| RING1 | 1572.0 |
| H3C2 | 1438.0 |
| CBX8 | 1425.0 |
| H2BC11 | 1338.0 |
| MAP4K4 | 1194.0 |
| H2AX | 499.0 |
| H2BC15 | 240.0 |
| MDM2 | 219.0 |
| CBX4 | 205.0 |
| EED | 94.0 |
| H2AZ1 | -360.0 |
| H3C3 | -546.0 |
| H2AC20 | -674.0 |
| MAPK1 | -857.0 |
| CDK6 | -1199.0 |
| H2BC6 | -1396.0 |
| AGO3 | -1413.0 |
| MAP2K4 | -2008.0 |
| MAP2K6 | -2038.0 |
| H2BC4 | -2094.0 |
| H2BC12 | -2115.0 |
| TFDP1 | -2156.0 |
| MAPK11 | -2236.0 |
| E2F3 | -2343.0 |
| EZH2 | -2415.0 |
| TNRC6A | -2432.0 |
| MAPK10 | -3279.0 |
| PHC3 | -3360.0 |
| IFNB1 | -3599.0 |
| TNRC6C | -3711.0 |
| UBA52 | -3755.0 |
| SCMH1 | -3933.0 |
| E2F2 | -4314.0 |
| H2BC9 | -4907.5 |
| H3C7 | -4907.5 |
| H4C5 | -4941.0 |
| MAPK3 | -5444.0 |
| H2BC21 | -5773.0 |
| RNF2 | -6542.0 |
| H2BC26 | -6695.0 |
| PHC2 | -6705.0 |
| H2AC14 | -8606.0 |
| MAPK8 | -8692.0 |
| H2BC14 | -8730.0 |
| MIR24-1 | -9122.0 |
| MINK1 | -9125.0 |
| H4C9 | -9282.0 |
| H2AC18 | -10224.5 |
| H2AC19 | -10224.5 |
REACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53
| 591 | |
|---|---|
| set | REACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53 |
| setSize | 351 |
| pANOVA | 0.000163 |
| s.dist | 0.117 |
| p.adjustANOVA | 0.00698 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| ELOB | 10991 |
| E2F1 | 10764 |
| TAF7 | 10601 |
| GADD45A | 10546 |
| POLR2K | 10402 |
| PRKAG1 | 10260 |
| CNOT8 | 10218 |
| AGO1 | 10212 |
| COX11 | 10031 |
| TAF6 | 10014 |
| TP53RK | 9916 |
| RGCC | 9838 |
| PIP4P1 | 9706 |
| CYCS | 9670 |
| PERP | 9660 |
| GPI | 9649 |
| JUN | 9609 |
| BID | 9555 |
| DDIT4 | 9511 |
| UBC | 9476 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ELOB | 10991 |
| E2F1 | 10764 |
| TAF7 | 10601 |
| GADD45A | 10546 |
| POLR2K | 10402 |
| PRKAG1 | 10260 |
| CNOT8 | 10218 |
| AGO1 | 10212 |
| COX11 | 10031 |
| TAF6 | 10014 |
| TP53RK | 9916 |
| RGCC | 9838 |
| PIP4P1 | 9706 |
| CYCS | 9670 |
| PERP | 9660 |
| GPI | 9649 |
| JUN | 9609 |
| BID | 9555 |
| DDIT4 | 9511 |
| UBC | 9476 |
| ELOC | 9413 |
| LAMTOR4 | 9268 |
| RAD1 | 9237 |
| KAT5 | 9221 |
| LRPPRC | 9205 |
| RABGGTB | 9195 |
| SESN2 | 9164 |
| CNOT11 | 9045 |
| TXN | 8969 |
| AURKB | 8795 |
| PIP4K2A | 8762 |
| TAF15 | 8749 |
| MAPK14 | 8739 |
| CSNK2B | 8721 |
| BARD1 | 8638 |
| LAMTOR2 | 8526 |
| COX4I1 | 8524 |
| MDM4 | 8496 |
| CDKN1B | 8453 |
| CCNH | 8435 |
| TAF13 | 8377 |
| PMS2 | 8329 |
| DNA2 | 8298 |
| GATAD2B | 8270 |
| TAF10 | 8254 |
| PRKAG3 | 8225 |
| TP53 | 8108 |
| TACO1 | 7999 |
| CNOT6 | 7981 |
| POLR2I | 7943 |
| RFFL | 7911 |
| PRR5 | 7860 |
| RBBP8 | 7822 |
| COX16 | 7805 |
| UBB | 7674 |
| ERCC2 | 7510 |
| KMT5A | 7432 |
| CCNB1 | 7396 |
| TAF1L | 7369 |
| PRELID1 | 7311 |
| CDKN2A | 7282 |
| CASP10 | 7274 |
| TPX2 | 7183 |
| BIRC5 | 7158 |
| RPS27A | 7120 |
| BCL2L14 | 7103 |
| GTF2H1 | 7100 |
| CDC25C | 7020 |
| GATAD2A | 7005 |
| CDK2 | 6939 |
| COX7C | 6918 |
| CHEK1 | 6909 |
| KAT6A | 6894 |
| TTC5 | 6881 |
| NPM1 | 6858 |
| RBBP4 | 6844 |
| SUPT16H | 6796 |
| CCNG1 | 6695 |
| MDC1 | 6671 |
| RHNO1 | 6649 |
| RAD9A | 6635 |
| CASP6 | 6582 |
| COX6C | 6519 |
| CHD4 | 6316 |
| BCL6 | 6221 |
| CDK12 | 6198 |
| MOV10 | 6170 |
| RRAGC | 6080 |
| TCEA1 | 6057 |
| TRIAP1 | 6007 |
| GTF2H3 | 5990 |
| AURKA | 5946 |
| YWHAB | 5879 |
| PMAIP1 | 5853 |
| PPP1R13L | 5846 |
| MLH1 | 5844 |
| PRDX1 | 5840 |
| TIGAR | 5827 |
| RPA1 | 5651 |
| MRE11 | 5620 |
| AGO4 | 5459 |
| HDAC2 | 5322 |
| SESN3 | 5150 |
| RBL2 | 5110 |
| CDKN1A | 5054 |
| TAF11 | 5030 |
| CCNT2 | 5011 |
| TP73 | 5000 |
| DAXX | 4994 |
| NDUFA4 | 4915 |
| E2F8 | 4845 |
| PCNA | 4821 |
| CSNK2A1 | 4697 |
| YWHAZ | 4655 |
| CNOT1 | 4620 |
| BRIP1 | 4606 |
| ATM | 4600 |
| SSRP1 | 4571 |
| NELFE | 4505 |
| SESN1 | 4424 |
| PRELID3A | 4322 |
| CTDP1 | 4247 |
| BLM | 4237 |
| TNRC6B | 4201 |
| NUAK1 | 4190 |
| ARID3A | 4176 |
| MBD3 | 4139 |
| BRD7 | 4133 |
| CSNK2A2 | 4122 |
| POLR2A | 3916 |
| LAMTOR5 | 3821 |
| COX6B1 | 3786 |
| NELFCD | 3781 |
| PPP1R13B | 3624 |
| ATF2 | 3606 |
| EXO1 | 3595 |
| CCNA1 | 3593 |
| PRDX5 | 3588 |
| PIP4K2B | 3579 |
| CHEK2 | 3413 |
| PPP2R5C | 3398 |
| MSH2 | 3394 |
| HUS1 | 3387 |
| BTG2 | 3356 |
| TFDP2 | 3339 |
| TAF5 | 3203 |
| CCNE2 | 3190 |
| POLR2E | 3177 |
| PRDM1 | 3158 |
| RFC2 | 3136 |
| PRMT5 | 3035 |
| GTF2F2 | 2945 |
| RRAGD | 2813 |
| TP53INP1 | 2810 |
| EHMT1 | 2779 |
| GLS | 2758 |
| YWHAH | 2697 |
| GLS2 | 2636 |
| POU4F2 | 2584 |
| IGFBP3 | 2553 |
| ERCC3 | 2481 |
| USP2 | 2480 |
| PPP2CA | 2292 |
| PRMT1 | 2256 |
| FOS | 2247 |
| COX20 | 2175 |
| MAPKAPK5 | 2167 |
| POLR2D | 2025 |
| ZNF420 | 1965 |
| GSR | 1919 |
| CENPJ | 1883 |
| BBC3 | 1846 |
| TXNRD1 | 1835 |
| BAX | 1761 |
| LAMTOR1 | 1723 |
| TAF4B | 1414 |
| SURF1 | 1393 |
| GTF2H4 | 1369 |
| CNOT4 | 1341 |
| EHMT2 | 1321 |
| CNOT9 | 1314 |
| TAF9 | 1265 |
| COX6A1 | 1217 |
| BRCA1 | 1120 |
| RPA2 | 1117 |
| CCNK | 1079 |
| MEAF6 | 1056 |
| PML | 1014 |
| CCNT1 | 863 |
| RFC4 | 824 |
| FANCD2 | 822 |
| YWHAE | 744 |
| RAD51D | 730 |
| DDB2 | 719 |
| ELOA | 667 |
| PIN1 | 606 |
| PCBP4 | 475 |
| PRKAB2 | 365 |
| HDAC1 | 346 |
| YWHAQ | 336 |
| ING2 | 309 |
| RAD17 | 283 |
| TOP3A | 244 |
| MDM2 | 219 |
| RAD9B | 45 |
| RFC5 | -81 |
| RABGGTA | -92 |
| TAF12 | -160 |
| COX5A | -245 |
| MTOR | -250 |
| RMI1 | -315 |
| TBP | -326 |
| TP53BP2 | -347 |
| RRM2B | -473 |
| TSC2 | -513 |
| CNOT7 | -539 |
| RBL1 | -621 |
| MNAT1 | -717 |
| LAMTOR3 | -947 |
| POLR2L | -971 |
| COX14 | -1185 |
| SGK1 | -1247 |
| RNF34 | -1258 |
| AGO3 | -1413 |
| USP7 | -1445 |
| DYRK2 | -1589 |
| NOC2L | -1604 |
| BNIP3L | -1658 |
| BRPF1 | -1677 |
| SETD9 | -1701 |
| ELL | -1756 |
| CASP2 | -1770 |
| CNOT2 | -1828 |
| POU4F1 | -1865 |
| MAPKAP1 | -1867 |
| YWHAG | -1887 |
| SLC38A9 | -1912 |
| PRDX2 | -1921 |
| PLK3 | -1922 |
| FAS | -1940 |
| PHF20 | -1999 |
| TSC1 | -2023 |
| MAP2K6 | -2038 |
| PTEN | -2093 |
| PPP2R1A | -2107 |
| TFDP1 | -2156 |
| JMY | -2164 |
| MAPK11 | -2236 |
| HIPK2 | -2250 |
| GTF2H5 | -2337 |
| EP300 | -2354 |
| CREBBP | -2409 |
| BANP | -2423 |
| TNRC6A | -2432 |
| AKT2 | -2480 |
| ING5 | -2508 |
| CNOT3 | -2521 |
| AKT1 | -2548 |
| COX18 | -2600 |
| PRKAB1 | -2706 |
| PRKAA1 | -2747 |
| PRKAG2 | -2851 |
| WRN | -2909 |
| COX5B | -3104 |
| TNFRSF10B | -3105 |
| L3MBTL1 | -3217 |
| POLR2B | -3234 |
| ELOA2 | -3237 |
| PRKAA2 | -3400 |
| TAF4 | -3407 |
| RICTOR | -3439 |
| CCNA2 | -3495 |
| CDK9 | -3594 |
| SMYD2 | -3601 |
| CARM1 | -3614 |
| TNRC6C | -3711 |
| PLK2 | -3722 |
| RMI2 | -3754 |
| UBA52 | -3755 |
| NBN | -3893 |
| NELFA | -3973 |
| RHEB | -4039 |
| SCO1 | -4041 |
| PIP4K2C | -4044 |
| APAF1 | -4071 |
| SCO2 | -4149 |
| PDPK1 | -4211 |
| SUPT5H | -4276 |
| COX7A2L | -4311 |
| RRAGA | -4390 |
| CNOT6L | -4491 |
| GTF2F1 | -4505 |
| ATR | -4506 |
| TAF3 | -4514 |
| CRADD | -4557 |
| TNFRSF10D | -4570 |
| CNOT10 | -4682 |
| GPX2 | -4690 |
| CDK5R1 | -4748 |
| POLR2F | -4762 |
| AGO2 | -4870 |
| TAF2 | -4881 |
| CDK7 | -4917 |
| NELFB | -4963 |
| RFC3 | -4967 |
| COX19 | -5160 |
| ATRIP | -5201 |
| COX8A | -5390 |
| PLAGL1 | -5415 |
| POLR2C | -5430 |
| AKT3 | -5586 |
| CHD3 | -5589 |
| CDK13 | -5608 |
| FANCC | -5640 |
| TOPBP1 | -5800 |
| POLR2J | -6011 |
| TNFRSF10A | -6065 |
| TNFRSF10C | -6105 |
| CDK1 | -6160 |
| MTA2 | -6196 |
| POLR2H | -6261 |
| RAD50 | -6431 |
| HIPK1 | -6525 |
| BRPF3 | -6592 |
| AIFM2 | -6613 |
| CDK5 | -6642 |
| E2F4 | -6771 |
| MLST8 | -6804 |
| TNKS1BP1 | -6850 |
| E2F7 | -6967 |
| STK11 | -7002 |
| TMEM219 | -7062 |
| SUPT4H1 | -7200 |
| PPP2CB | -7216 |
| STEAP3 | -7284 |
| PIDD1 | -7542 |
| TP63 | -8024 |
| RPTOR | -8028 |
| RPA3 | -8086 |
| NLRC4 | -8113 |
| ZNF385A | -8149 |
| PPP2R1B | -8245 |
| POLR2G | -8279 |
| TP53I3 | -8454 |
| BRD1 | -8478 |
| FANCI | -8803 |
| CASP1 | -9200 |
| SFN | -9368 |
| NDRG1 | -9608 |
| CCNE1 | -9930 |
| TP53AIP1 | -10087 |
REACTOME_SEPARATION_OF_SISTER_CHROMATIDS
| 492 | |
|---|---|
| set | REACTOME_SEPARATION_OF_SISTER_CHROMATIDS |
| setSize | 184 |
| pANOVA | 0.000166 |
| s.dist | 0.161 |
| p.adjustANOVA | 0.00698 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CENPQ | 10378 |
| PSMD12 | 10325 |
| DYNC1LI2 | 10216 |
| PSMC6 | 9977 |
| ESPL1 | 9956 |
| KNTC1 | 9932 |
| PSMB3 | 9858 |
| UBC | 9476 |
| DSN1 | 9391 |
| TUBB6 | 9058 |
| PPP2R5B | 9055 |
| ZWINT | 8928 |
| BUB1B | 8870 |
| AURKB | 8795 |
| PPP2R5D | 8711 |
| ITGB3BP | 8707 |
| PSME2 | 8685 |
| CLIP1 | 8357 |
| TUBAL3 | 8355 |
| DYNLL2 | 8325 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CENPQ | 10378 |
| PSMD12 | 10325 |
| DYNC1LI2 | 10216 |
| PSMC6 | 9977 |
| ESPL1 | 9956 |
| KNTC1 | 9932 |
| PSMB3 | 9858 |
| UBC | 9476 |
| DSN1 | 9391 |
| TUBB6 | 9058 |
| PPP2R5B | 9055 |
| ZWINT | 8928 |
| BUB1B | 8870 |
| AURKB | 8795 |
| PPP2R5D | 8711 |
| ITGB3BP | 8707 |
| PSME2 | 8685 |
| CLIP1 | 8357 |
| TUBAL3 | 8355 |
| DYNLL2 | 8325 |
| PSMB4 | 8180 |
| TUBB4B | 7956 |
| PSMD13 | 7901 |
| TUBB3 | 7767 |
| CENPM | 7709 |
| PSME4 | 7705 |
| CENPL | 7683 |
| UBB | 7674 |
| PSMB2 | 7641 |
| NDC80 | 7594 |
| AHCTF1 | 7417 |
| PSMB11 | 7359 |
| TUBA8 | 7215 |
| PSMA6 | 7190 |
| BIRC5 | 7158 |
| RPS27A | 7120 |
| PSMA1 | 7018 |
| ANAPC11 | 6955 |
| SEH1L | 6838 |
| TUBB8 | 6817 |
| BUB1 | 6792 |
| TUBB2B | 6768 |
| RAD21 | 6706 |
| NUP85 | 6688 |
| PSMD3 | 6672 |
| CENPC | 6615 |
| NUP37 | 6306 |
| ZW10 | 6123 |
| SKA2 | 6014 |
| NUP43 | 5921 |
| KNL1 | 5868 |
| ANAPC10 | 5865 |
| CKAP5 | 5856 |
| B9D2 | 5784 |
| CENPT | 5768 |
| PDS5B | 5760 |
| PSMC1 | 5715 |
| SGO2 | 5675 |
| PSMD2 | 5624 |
| PAFAH1B1 | 5441 |
| PSMA5 | 5362 |
| PLK1 | 5347 |
| ANAPC2 | 5346 |
| KIF2C | 5265 |
| SMC3 | 5251 |
| PSMA4 | 5246 |
| PSMC5 | 5193 |
| NUP107 | 5069 |
| RCC2 | 4920 |
| CDC20 | 4753 |
| RPS27 | 4711 |
| SPC25 | 4707 |
| NUP133 | 4676 |
| ANAPC5 | 4671 |
| KIF18A | 4448 |
| MAD2L1 | 4439 |
| NSL1 | 4358 |
| PSMF1 | 4311 |
| PMF1 | 4232 |
| PSMD1 | 4227 |
| PSME3 | 4172 |
| CENPE | 4143 |
| PSMC2 | 4088 |
| CENPS | 4026 |
| CDCA8 | 3983 |
| PSMA8 | 3923 |
| PSMA7 | 3903 |
| PSME1 | 3866 |
| PSMA3 | 3850 |
| MAPRE1 | 3644 |
| PSMB9 | 3459 |
| PPP2R5C | 3398 |
| WAPL | 3291 |
| CENPF | 3253 |
| CDC27 | 3049 |
| PSMC4 | 3004 |
| NUF2 | 2983 |
| PSMC3 | 2960 |
| RANBP2 | 2651 |
| SEM1 | 2517 |
| CDC26 | 2306 |
| PPP2CA | 2292 |
| ANAPC15 | 1950 |
| CDC23 | 1927 |
| BUB3 | 1906 |
| SGO1 | 1729 |
| CENPK | 1710 |
| TUBA4A | 938 |
| CDC16 | 754 |
| TUBA4B | 650 |
| NDEL1 | 641 |
| PSMD11 | 620 |
| PDS5A | 449 |
| PSMB8 | 447 |
| DYNC1LI1 | 233 |
| MIS12 | 15 |
| PSMA2 | -85 |
| PPP2R5A | -152 |
| DYNC1I1 | -202 |
| ANAPC4 | -310 |
| NUP98 | -351 |
| DYNC1I2 | -440 |
| TUBB1 | -584 |
| PSMD14 | -865 |
| CENPO | -914 |
| PSMD6 | -961 |
| SPDL1 | -977 |
| ANAPC1 | -1043 |
| XPO1 | -1083 |
| PSMB7 | -1294 |
| PTTG1 | -1320 |
| UBE2S | -1361 |
| NUDC | -1567 |
| CLASP1 | -2048 |
| PPP2R1A | -2107 |
| CENPN | -2163 |
| CLASP2 | -2170 |
| ZWILCH | -2190 |
| PSMB10 | -2290 |
| PSMB6 | -2408 |
| PPP2R5E | -2509 |
| UBE2C | -2539 |
| PSMD9 | -2570 |
| UBE2E1 | -2647 |
| PPP1CC | -3102 |
| STAG1 | -3331 |
| SPC24 | -3429 |
| DYNLL1 | -3541 |
| UBA52 | -3755 |
| ANAPC7 | -3780 |
| RANGAP1 | -3961 |
| TUBA1C | -4357 |
| TUBA1B | -4469 |
| ANAPC16 | -4502 |
| PSMB5 | -4687 |
| PSMD7 | -5198 |
| TAOK1 | -5237 |
| TUBA3D | -5264 |
| INCENP | -5274 |
| PSMD4 | -5337 |
| UBE2D1 | -5394 |
| SEC13 | -5670 |
| NDE1 | -5839 |
| PSMB1 | -5858 |
| MAD1L1 | -6006 |
| DYNC1H1 | -6092 |
| CENPU | -6349 |
| SKA1 | -6910 |
| KIF2A | -6979 |
| CDCA5 | -7077 |
| NUP160 | -7169 |
| PPP2CB | -7216 |
| TUBB4A | -7633 |
| PSMD8 | -7723 |
| CENPP | -7911 |
| TUBA1A | -8056 |
| PPP2R1B | -8245 |
| CENPH | -8704 |
| KIF2B | -8857 |
| TUBB2A | -9511 |
| PSMD5 | -9524 |
| CENPA | -9945 |
| TUBA3C | -10220 |
| TUBA3E | -10574 |
REACTOME_DNA_REPAIR
| 1168 | |
|---|---|
| set | REACTOME_DNA_REPAIR |
| setSize | 321 |
| pANOVA | 0.000198 |
| s.dist | 0.121 |
| p.adjustANOVA | 0.00814 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| H4C8 | 10752 |
| INO80B | 10627 |
| POLE3 | 10464 |
| POLR2K | 10402 |
| POLD4 | 10382 |
| SUMO2 | 10371 |
| LIG3 | 10252 |
| MUS81 | 10150 |
| SIRT6 | 10149 |
| XPA | 10037 |
| WDR48 | 10007 |
| H2AJ | 9870 |
| HMGN1 | 9811 |
| ALKBH5 | 9802 |
| ACTB | 9643 |
| UBE2T | 9616 |
| UBA7 | 9564 |
| INO80C | 9534 |
| UBC | 9476 |
| DCLRE1B | 9396 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| H4C8 | 10752.0 |
| INO80B | 10627.0 |
| POLE3 | 10464.0 |
| POLR2K | 10402.0 |
| POLD4 | 10382.0 |
| SUMO2 | 10371.0 |
| LIG3 | 10252.0 |
| MUS81 | 10150.0 |
| SIRT6 | 10149.0 |
| XPA | 10037.0 |
| WDR48 | 10007.0 |
| H2AJ | 9870.0 |
| HMGN1 | 9811.0 |
| ALKBH5 | 9802.0 |
| ACTB | 9643.0 |
| UBE2T | 9616.0 |
| UBA7 | 9564.0 |
| INO80C | 9534.0 |
| UBC | 9476.0 |
| DCLRE1B | 9396.0 |
| COPS5 | 9364.0 |
| PIAS1 | 9344.0 |
| RBX1 | 9293.0 |
| BABAM1 | 9283.0 |
| RAD1 | 9237.0 |
| KAT5 | 9221.0 |
| ALKBH2 | 9129.0 |
| MSH6 | 9094.0 |
| FEN1 | 9002.0 |
| ISG15 | 8922.0 |
| FANCF | 8885.0 |
| H4C12 | 8883.0 |
| PPP4R2 | 8851.0 |
| H4C2 | 8690.0 |
| BARD1 | 8638.0 |
| H2BC13 | 8609.0 |
| CCNH | 8435.0 |
| COPS7A | 8431.0 |
| H2BC1 | 8383.0 |
| RAD51AP1 | 8345.0 |
| PMS2 | 8329.0 |
| DNA2 | 8298.0 |
| PARP1 | 8191.0 |
| TP53 | 8108.0 |
| POLR2I | 7943.0 |
| OGG1 | 7828.0 |
| RBBP8 | 7822.0 |
| H2AZ2 | 7814.0 |
| H2AC7 | 7754.5 |
| H2BC7 | 7754.5 |
| RNF111 | 7746.0 |
| XAB2 | 7738.0 |
| SUMO3 | 7732.0 |
| UBB | 7674.0 |
| RNF4 | 7654.0 |
| MBD4 | 7627.0 |
| DCLRE1A | 7585.0 |
| ERCC2 | 7510.0 |
| FAAP20 | 7489.0 |
| UFD1 | 7487.0 |
| UBXN1 | 7471.0 |
| POLD1 | 7462.0 |
| ABRAXAS1 | 7372.0 |
| MAD2L2 | 7328.0 |
| H4C16 | 7260.0 |
| RAD51C | 7257.0 |
| MPG | 7228.0 |
| POLH | 7182.0 |
| RPS27A | 7120.0 |
| GTF2H1 | 7100.0 |
| DCLRE1C | 7047.0 |
| CDK2 | 6939.0 |
| CHEK1 | 6909.0 |
| MDC1 | 6671.0 |
| RHNO1 | 6649.0 |
| RAD9A | 6635.0 |
| H2AC8 | 6630.0 |
| LIG4 | 6572.0 |
| EME2 | 6383.0 |
| RNF8 | 6146.0 |
| H2BC8 | 6087.0 |
| TCEA1 | 6057.0 |
| DTL | 6019.0 |
| GTF2H3 | 5990.0 |
| H4C3 | 5935.0 |
| FANCE | 5908.0 |
| H4C1 | 5864.0 |
| MLH1 | 5844.0 |
| EYA3 | 5837.0 |
| UBE2B | 5757.0 |
| USP43 | 5749.0 |
| NEIL1 | 5663.0 |
| RPA1 | 5651.0 |
| MRE11 | 5620.0 |
| NEIL2 | 5228.0 |
| H2BC5 | 5130.0 |
| NHEJ1 | 5017.0 |
| H4C6 | 4952.0 |
| FANCM | 4945.0 |
| TERF2 | 4935.0 |
| POLK | 4853.0 |
| PCNA | 4821.0 |
| H2BC3 | 4658.0 |
| H4C13 | 4630.0 |
| XRCC6 | 4619.0 |
| PRPF19 | 4618.0 |
| BRIP1 | 4606.0 |
| ATM | 4600.0 |
| H4C11 | 4553.0 |
| POLB | 4470.0 |
| NEIL3 | 4419.0 |
| NTHL1 | 4289.0 |
| REV3L | 4283.0 |
| UBE2I | 4265.0 |
| BLM | 4237.0 |
| INO80 | 4157.0 |
| ASCC2 | 4047.0 |
| CENPS | 4026.0 |
| H2BC10 | 3947.0 |
| POLR2A | 3916.0 |
| H4C4 | 3785.0 |
| KPNA2 | 3680.0 |
| ADPRS | 3670.0 |
| EXO1 | 3595.0 |
| CCNA1 | 3593.0 |
| ERCC1 | 3475.0 |
| TIMELESS | 3418.0 |
| CHEK2 | 3413.0 |
| MSH2 | 3394.0 |
| HUS1 | 3387.0 |
| H2BC17 | 3276.0 |
| POLR2E | 3177.0 |
| RFC2 | 3136.0 |
| PCLAF | 3072.0 |
| POLE4 | 3064.0 |
| BAZ1B | 3050.0 |
| POLQ | 3031.0 |
| H2AC6 | 2946.0 |
| ERCC6 | 2881.0 |
| BRCA2 | 2796.0 |
| ISY1 | 2794.0 |
| GEN1 | 2595.0 |
| PIAS3 | 2547.0 |
| SEM1 | 2517.0 |
| ERCC3 | 2481.0 |
| COPS3 | 2465.0 |
| COPS2 | 2464.0 |
| H2AC4 | 2379.0 |
| UBE2N | 2342.0 |
| H3-4 | 2030.0 |
| POLR2D | 2025.0 |
| RAD52 | 1823.0 |
| TINF2 | 1779.0 |
| ASCC3 | 1610.0 |
| POLN | 1567.0 |
| XPC | 1565.0 |
| CUL4A | 1378.0 |
| GTF2H4 | 1369.0 |
| H2BC11 | 1338.0 |
| EYA2 | 1333.0 |
| XRCC2 | 1259.0 |
| CHD1L | 1189.0 |
| FAAP100 | 1178.0 |
| APEX1 | 1145.0 |
| BRCA1 | 1120.0 |
| RPA2 | 1117.0 |
| XRCC4 | 999.0 |
| RFC4 | 824.0 |
| FANCD2 | 822.0 |
| RAD51D | 730.0 |
| DDB2 | 719.0 |
| XRCC5 | 699.0 |
| SMUG1 | 696.0 |
| REV1 | 666.0 |
| USP10 | 546.0 |
| H2AX | 499.0 |
| TRIM25 | 479.0 |
| XRCC1 | 478.0 |
| RAD23B | 465.0 |
| POLD2 | 347.0 |
| RAD17 | 283.0 |
| TOP3A | 244.0 |
| H2BC15 | 240.0 |
| SMARCA5 | 228.0 |
| POLE2 | 60.0 |
| UIMC1 | 46.0 |
| RAD9B | 45.0 |
| ACTR5 | -8.0 |
| RFC5 | -81.0 |
| FAN1 | -129.0 |
| TFPT | -231.0 |
| USP45 | -240.0 |
| NSD2 | -277.0 |
| RMI1 | -315.0 |
| H2AZ1 | -360.0 |
| COPS4 | -405.0 |
| UBE2V2 | -500.0 |
| MUTYH | -520.0 |
| ERCC5 | -526.0 |
| POLM | -592.0 |
| POT1 | -662.0 |
| H2AC20 | -674.0 |
| MCRS1 | -703.0 |
| MNAT1 | -717.0 |
| AQR | -718.0 |
| INO80E | -907.0 |
| POLR2L | -971.0 |
| RAD18 | -1007.0 |
| KDM4A | -1030.0 |
| PARP2 | -1132.0 |
| PPP4C | -1188.0 |
| PRKDC | -1203.0 |
| H2BC6 | -1396.0 |
| ZNF830 | -1443.0 |
| USP7 | -1445.0 |
| LIG1 | -1478.0 |
| ACD | -1494.5 |
| ASCC1 | -1512.0 |
| RTEL1 | -1529.0 |
| GPS1 | -1624.0 |
| TDP1 | -1678.0 |
| ELL | -1756.0 |
| UNG | -1766.0 |
| COPS6 | -1780.0 |
| MSH3 | -1873.0 |
| YY1 | -1989.0 |
| BAP1 | -2090.0 |
| H2BC4 | -2094.0 |
| H2BC12 | -2115.0 |
| POLL | -2119.0 |
| TP53BP1 | -2175.0 |
| GTF2H5 | -2337.0 |
| EP300 | -2354.0 |
| INO80D | -2417.0 |
| RCHY1 | -2504.0 |
| SUMO1 | -2534.0 |
| PIAS4 | -2542.0 |
| NFRKB | -2610.0 |
| CLSPN | -2700.0 |
| PAXIP1 | -2818.0 |
| ACTR8 | -2899.0 |
| WRN | -2909.0 |
| NPLOC4 | -2913.0 |
| EYA1 | -2949.0 |
| RUVBL1 | -2958.0 |
| COPS7B | -3053.0 |
| HERC2 | -3058.0 |
| TERF1 | -3138.0 |
| POLR2B | -3234.0 |
| TDG | -3450.0 |
| FTO | -3494.0 |
| CCNA2 | -3495.0 |
| SPIDR | -3620.0 |
| RMI2 | -3754.0 |
| UBA52 | -3755.0 |
| POLI | -3804.0 |
| NBN | -3893.0 |
| TERF2IP | -3905.0 |
| RFC1 | -3990.0 |
| DDB1 | -4024.0 |
| PALB2 | -4029.0 |
| PNKP | -4040.0 |
| RAD51 | -4393.0 |
| ATR | -4506.0 |
| SPRTN | -4584.0 |
| EYA4 | -4652.0 |
| TIPIN | -4702.0 |
| RAD51B | -4712.0 |
| POLR2F | -4762.0 |
| PARG | -4892.0 |
| H2BC9 | -4907.5 |
| CDK7 | -4917.0 |
| H4C5 | -4941.0 |
| RFC3 | -4967.0 |
| FAAP24 | -5051.0 |
| ATRIP | -5201.0 |
| RNF168 | -5219.0 |
| POLD3 | -5419.0 |
| ALKBH3 | -5424.0 |
| POLR2C | -5430.0 |
| ERCC4 | -5636.0 |
| FANCC | -5640.0 |
| SLX4 | -5644.0 |
| APBB1 | -5736.0 |
| EME1 | -5745.0 |
| H2BC21 | -5773.0 |
| TOPBP1 | -5800.0 |
| USP1 | -5861.0 |
| POLR2J | -6011.0 |
| ERCC8 | -6029.0 |
| BABAM2 | -6094.0 |
| ACTL6A | -6145.0 |
| UVSSA | -6152.0 |
| POLR2H | -6261.0 |
| KDM4B | -6329.0 |
| FANCL | -6345.0 |
| RAD50 | -6431.0 |
| PPIE | -6522.0 |
| FANCA | -6612.0 |
| UBE2L6 | -6675.0 |
| H2BC26 | -6695.0 |
| PPP5C | -6872.0 |
| RIF1 | -6924.0 |
| XRCC3 | -7042.0 |
| VCP | -7056.0 |
| COPS8 | -7382.0 |
| RAD23A | -7675.0 |
| FANCG | -8051.0 |
| RPA3 | -8086.0 |
| POLR2G | -8279.0 |
| ABL1 | -8289.0 |
| POLE | -8297.0 |
| H2AC14 | -8606.0 |
| MAPK8 | -8692.0 |
| H2BC14 | -8730.0 |
| MGMT | -8786.0 |
| FANCI | -8803.0 |
| TDP2 | -8965.0 |
| H4C9 | -9282.0 |
| H2AC18 | -10224.5 |
| H2AC19 | -10224.5 |
REACTOME_RNA_POLYMERASE_I_PROMOTER_ESCAPE
| 1157 | |
|---|---|
| set | REACTOME_RNA_POLYMERASE_I_PROMOTER_ESCAPE |
| setSize | 83 |
| pANOVA | 0.000223 |
| s.dist | 0.234 |
| p.adjustANOVA | 0.00892 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| H4C8 | 10752.0 |
| POLR2K | 10402.0 |
| H2AJ | 9870.0 |
| H3C10 | 9015.0 |
| H3C11 | 8963.0 |
| H4C12 | 8883.0 |
| H4C2 | 8690.0 |
| POLR1C | 8652.0 |
| H3-3A | 8639.0 |
| H2BC13 | 8609.0 |
| CCNH | 8435.0 |
| H2BC1 | 8383.0 |
| POLR1G | 8105.0 |
| H3C12 | 8052.0 |
| POLR1E | 7865.0 |
| TAF1A | 7863.0 |
| H2AZ2 | 7814.0 |
| H2AC7 | 7754.5 |
| H2BC7 | 7754.5 |
| ERCC2 | 7510.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| H4C8 | 10752.0 |
| POLR2K | 10402.0 |
| H2AJ | 9870.0 |
| H3C10 | 9015.0 |
| H3C11 | 8963.0 |
| H4C12 | 8883.0 |
| H4C2 | 8690.0 |
| POLR1C | 8652.0 |
| H3-3A | 8639.0 |
| H2BC13 | 8609.0 |
| CCNH | 8435.0 |
| H2BC1 | 8383.0 |
| POLR1G | 8105.0 |
| H3C12 | 8052.0 |
| POLR1E | 7865.0 |
| TAF1A | 7863.0 |
| H2AZ2 | 7814.0 |
| H2AC7 | 7754.5 |
| H2BC7 | 7754.5 |
| ERCC2 | 7510.0 |
| H4C16 | 7260.0 |
| POLR1A | 7244.0 |
| GTF2H1 | 7100.0 |
| UBTF | 6988.0 |
| H2AC8 | 6630.0 |
| CBX3 | 6210.0 |
| POLR1B | 6206.0 |
| H3-3B | 6110.0 |
| H2BC8 | 6087.0 |
| GTF2H3 | 5990.0 |
| H4C3 | 5935.0 |
| H4C1 | 5864.0 |
| H3C1 | 5598.0 |
| H2BC5 | 5130.0 |
| H4C6 | 4952.0 |
| H3C4 | 4718.0 |
| H2BC3 | 4658.0 |
| H4C13 | 4630.0 |
| H4C11 | 4553.0 |
| POLR1H | 4220.0 |
| TAF1B | 4095.0 |
| H2BC10 | 3947.0 |
| H4C4 | 3785.0 |
| POLR1D | 3345.0 |
| H2BC17 | 3276.0 |
| POLR2E | 3177.0 |
| H3C6 | 3009.0 |
| H2AC6 | 2946.0 |
| H3C8 | 2699.0 |
| ERCC3 | 2481.0 |
| H2AC4 | 2379.0 |
| H3C2 | 1438.0 |
| GTF2H4 | 1369.0 |
| H2BC11 | 1338.0 |
| RRN3 | 1080.0 |
| TAF1D | 1064.0 |
| H2AX | 499.0 |
| POLR1F | 404.0 |
| H2BC15 | 240.0 |
| TBP | -326.0 |
| H2AZ1 | -360.0 |
| H3C3 | -546.0 |
| H2AC20 | -674.0 |
| MNAT1 | -717.0 |
| POLR2L | -971.0 |
| H2BC6 | -1396.0 |
| H2BC4 | -2094.0 |
| H2BC12 | -2115.0 |
| GTF2H5 | -2337.0 |
| TAF1C | -3698.0 |
| POLR2F | -4762.0 |
| H2BC9 | -4907.5 |
| H3C7 | -4907.5 |
| CDK7 | -4917.0 |
| H4C5 | -4941.0 |
| H2BC21 | -5773.0 |
| POLR2H | -6261.0 |
| H2BC26 | -6695.0 |
| H2AC14 | -8606.0 |
| H2BC14 | -8730.0 |
| H4C9 | -9282.0 |
| H2AC18 | -10224.5 |
| H2AC19 | -10224.5 |
REACTOME_SENESCENCE_ASSOCIATED_SECRETORY_PHENOTYPE_SASP
| 502 | |
|---|---|
| set | REACTOME_SENESCENCE_ASSOCIATED_SECRETORY_PHENOTYPE_SASP |
| setSize | 104 |
| pANOVA | 0.000247 |
| s.dist | 0.208 |
| p.adjustANOVA | 0.00966 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CDKN2D | 10762 |
| H4C8 | 10752 |
| CDK4 | 10506 |
| CDKN2B | 10314 |
| H2AJ | 9870 |
| JUN | 9609 |
| CXCL8 | 9558 |
| UBC | 9476 |
| STAT3 | 9471 |
| IL6 | 9220 |
| H3C10 | 9015 |
| H3C11 | 8963 |
| H4C12 | 8883 |
| H4C2 | 8690 |
| H3-3A | 8639 |
| H2BC13 | 8609 |
| CDKN1B | 8453 |
| H2BC1 | 8383 |
| H3C12 | 8052 |
| H2AZ2 | 7814 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CDKN2D | 10762.0 |
| H4C8 | 10752.0 |
| CDK4 | 10506.0 |
| CDKN2B | 10314.0 |
| H2AJ | 9870.0 |
| JUN | 9609.0 |
| CXCL8 | 9558.0 |
| UBC | 9476.0 |
| STAT3 | 9471.0 |
| IL6 | 9220.0 |
| H3C10 | 9015.0 |
| H3C11 | 8963.0 |
| H4C12 | 8883.0 |
| H4C2 | 8690.0 |
| H3-3A | 8639.0 |
| H2BC13 | 8609.0 |
| CDKN1B | 8453.0 |
| H2BC1 | 8383.0 |
| H3C12 | 8052.0 |
| H2AZ2 | 7814.0 |
| H2AC7 | 7754.5 |
| H2BC7 | 7754.5 |
| VENTX | 7728.0 |
| UBB | 7674.0 |
| CDKN2A | 7282.0 |
| H4C16 | 7260.0 |
| RPS27A | 7120.0 |
| ANAPC11 | 6955.0 |
| CDK2 | 6939.0 |
| H2AC8 | 6630.0 |
| H3-3B | 6110.0 |
| H2BC8 | 6087.0 |
| H4C3 | 5935.0 |
| ANAPC10 | 5865.0 |
| H4C1 | 5864.0 |
| H3C1 | 5598.0 |
| ANAPC2 | 5346.0 |
| H2BC5 | 5130.0 |
| CDKN1A | 5054.0 |
| H4C6 | 4952.0 |
| H3C4 | 4718.0 |
| CEBPB | 4682.0 |
| ANAPC5 | 4671.0 |
| H2BC3 | 4658.0 |
| H4C13 | 4630.0 |
| H4C11 | 4553.0 |
| RPS6KA1 | 4484.0 |
| H2BC10 | 3947.0 |
| H4C4 | 3785.0 |
| CCNA1 | 3593.0 |
| CDKN2C | 3429.0 |
| H2BC17 | 3276.0 |
| CDC27 | 3049.0 |
| H3C6 | 3009.0 |
| H2AC6 | 2946.0 |
| EHMT1 | 2779.0 |
| H3C8 | 2699.0 |
| H2AC4 | 2379.0 |
| CDC26 | 2306.0 |
| FOS | 2247.0 |
| ANAPC15 | 1950.0 |
| CDC23 | 1927.0 |
| IL1A | 1611.0 |
| H3C2 | 1438.0 |
| H2BC11 | 1338.0 |
| EHMT2 | 1321.0 |
| CDC16 | 754.0 |
| H2AX | 499.0 |
| H2BC15 | 240.0 |
| FZR1 | 16.0 |
| ANAPC4 | -310.0 |
| H2AZ1 | -360.0 |
| H3C3 | -546.0 |
| H2AC20 | -674.0 |
| MAPK1 | -857.0 |
| ANAPC1 | -1043.0 |
| CDK6 | -1199.0 |
| MAPK7 | -1357.0 |
| UBE2S | -1361.0 |
| H2BC6 | -1396.0 |
| H2BC4 | -2094.0 |
| H2BC12 | -2115.0 |
| UBE2C | -2539.0 |
| UBE2E1 | -2647.0 |
| RPS6KA2 | -2842.0 |
| CCNA2 | -3495.0 |
| UBA52 | -3755.0 |
| ANAPC7 | -3780.0 |
| ANAPC16 | -4502.0 |
| H2BC9 | -4907.5 |
| H3C7 | -4907.5 |
| H4C5 | -4941.0 |
| UBE2D1 | -5394.0 |
| MAPK3 | -5444.0 |
| H2BC21 | -5773.0 |
| H2BC26 | -6695.0 |
| NFKB1 | -7273.0 |
| IGFBP7 | -7794.0 |
| RELA | -8093.0 |
| H2AC14 | -8606.0 |
| H2BC14 | -8730.0 |
| H4C9 | -9282.0 |
| H2AC18 | -10224.5 |
| H2AC19 | -10224.5 |
REACTOME_POSITIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION
| 851 | |
|---|---|
| set | REACTOME_POSITIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION |
| setSize | 98 |
| pANOVA | 0.000269 |
| s.dist | 0.213 |
| p.adjustANOVA | 0.0103 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| H4C8 | 10752 |
| POLR2K | 10402 |
| H2AJ | 9870 |
| ACTB | 9643 |
| DEK | 9433 |
| H3C10 | 9015 |
| H3C11 | 8963 |
| H4C12 | 8883 |
| KAT2B | 8850 |
| H4C2 | 8690 |
| POLR1C | 8652 |
| H3-3A | 8639 |
| H2BC13 | 8609 |
| H2BC1 | 8383 |
| GATAD2B | 8270 |
| POLR1G | 8105 |
| H3C12 | 8052 |
| DDX21 | 7989 |
| POLR1E | 7865 |
| TAF1A | 7863 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| H4C8 | 10752.0 |
| POLR2K | 10402.0 |
| H2AJ | 9870.0 |
| ACTB | 9643.0 |
| DEK | 9433.0 |
| H3C10 | 9015.0 |
| H3C11 | 8963.0 |
| H4C12 | 8883.0 |
| KAT2B | 8850.0 |
| H4C2 | 8690.0 |
| POLR1C | 8652.0 |
| H3-3A | 8639.0 |
| H2BC13 | 8609.0 |
| H2BC1 | 8383.0 |
| GATAD2B | 8270.0 |
| POLR1G | 8105.0 |
| H3C12 | 8052.0 |
| DDX21 | 7989.0 |
| POLR1E | 7865.0 |
| TAF1A | 7863.0 |
| H2AZ2 | 7814.0 |
| H2AC7 | 7754.5 |
| H2BC7 | 7754.5 |
| H4C16 | 7260.0 |
| POLR1A | 7244.0 |
| GATAD2A | 7005.0 |
| RBBP4 | 6844.0 |
| H2AC8 | 6630.0 |
| CHD4 | 6316.0 |
| CBX3 | 6210.0 |
| POLR1B | 6206.0 |
| H3-3B | 6110.0 |
| H2BC8 | 6087.0 |
| H4C3 | 5935.0 |
| H4C1 | 5864.0 |
| H3C1 | 5598.0 |
| MYO1C | 5390.0 |
| HDAC2 | 5322.0 |
| H2BC5 | 5130.0 |
| H4C6 | 4952.0 |
| H3C4 | 4718.0 |
| H2BC3 | 4658.0 |
| H4C13 | 4630.0 |
| H4C11 | 4553.0 |
| SF3B1 | 4515.0 |
| POLR1H | 4220.0 |
| MBD3 | 4139.0 |
| TAF1B | 4095.0 |
| H2BC10 | 3947.0 |
| H4C4 | 3785.0 |
| POLR1D | 3345.0 |
| H2BC17 | 3276.0 |
| POLR2E | 3177.0 |
| BAZ1B | 3050.0 |
| H3C6 | 3009.0 |
| H2AC6 | 2946.0 |
| ERCC6 | 2881.0 |
| H3C8 | 2699.0 |
| H2AC4 | 2379.0 |
| H3C2 | 1438.0 |
| H2BC11 | 1338.0 |
| EHMT2 | 1321.0 |
| TAF1D | 1064.0 |
| H2AX | 499.0 |
| POLR1F | 404.0 |
| HDAC1 | 346.0 |
| H2BC15 | 240.0 |
| SMARCA5 | 228.0 |
| TBP | -326.0 |
| H2AZ1 | -360.0 |
| H3C3 | -546.0 |
| H2AC20 | -674.0 |
| POLR2L | -971.0 |
| H2BC6 | -1396.0 |
| H2BC4 | -2094.0 |
| MYBBP1A | -2101.0 |
| H2BC12 | -2115.0 |
| EP300 | -2354.0 |
| TTF1 | -3316.0 |
| TAF1C | -3698.0 |
| MTA1 | -4459.0 |
| MTA3 | -4477.0 |
| POLR2F | -4762.0 |
| H2BC9 | -4907.5 |
| H3C7 | -4907.5 |
| H4C5 | -4941.0 |
| CHD3 | -5589.0 |
| H2BC21 | -5773.0 |
| GSK3B | -6007.0 |
| MTA2 | -6196.0 |
| POLR2H | -6261.0 |
| KAT2A | -6518.0 |
| H2BC26 | -6695.0 |
| H2AC14 | -8606.0 |
| H2BC14 | -8730.0 |
| H4C9 | -9282.0 |
| H2AC18 | -10224.5 |
| H2AC19 | -10224.5 |
REACTOME_SIGNALING_BY_CSF3_G_CSF
| 1535 | |
|---|---|
| set | REACTOME_SIGNALING_BY_CSF3_G_CSF |
| setSize | 30 |
| pANOVA | 0.00032 |
| s.dist | 0.38 |
| p.adjustANOVA | 0.0118 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| ELOB | 10991 |
| PTPN11 | 10353 |
| RNF7 | 9796 |
| UBC | 9476 |
| STAT3 | 9471 |
| ELOC | 9413 |
| STAT5A | 9217 |
| SYK | 8993 |
| LYN | 8661 |
| SHC1 | 8640 |
| GRB2 | 8138 |
| JAK1 | 8034 |
| UBB | 7674 |
| RPS27A | 7120 |
| HCK | 6499 |
| STAT5B | 5614 |
| CUL5 | 5014 |
| KRAS | 4814 |
| SOCS1 | 4294 |
| UBE2D2 | 3677 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ELOB | 10991 |
| PTPN11 | 10353 |
| RNF7 | 9796 |
| UBC | 9476 |
| STAT3 | 9471 |
| ELOC | 9413 |
| STAT5A | 9217 |
| SYK | 8993 |
| LYN | 8661 |
| SHC1 | 8640 |
| GRB2 | 8138 |
| JAK1 | 8034 |
| UBB | 7674 |
| RPS27A | 7120 |
| HCK | 6499 |
| STAT5B | 5614 |
| CUL5 | 5014 |
| KRAS | 4814 |
| SOCS1 | 4294 |
| UBE2D2 | 3677 |
| CSF3R | 3484 |
| UBE2D3 | 2976 |
| GAB2 | 2042 |
| STAT1 | 1103 |
| JAK2 | -2410 |
| UBA52 | -3755 |
| UBE2D1 | -5394 |
| TYK2 | -7870 |
| SOCS3 | -8251 |
| CSF3 | -8388 |
REACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION
| 852 | |
|---|---|
| set | REACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION |
| setSize | 84 |
| pANOVA | 0.000324 |
| s.dist | 0.227 |
| p.adjustANOVA | 0.0118 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| H4C8 | 10752 |
| POLR2K | 10402 |
| H2AJ | 9870 |
| ACTB | 9643 |
| DEK | 9433 |
| H3C10 | 9015 |
| H3C11 | 8963 |
| H4C12 | 8883 |
| KAT2B | 8850 |
| H4C2 | 8690 |
| POLR1C | 8652 |
| H3-3A | 8639 |
| H2BC13 | 8609 |
| H2BC1 | 8383 |
| POLR1G | 8105 |
| H3C12 | 8052 |
| DDX21 | 7989 |
| POLR1E | 7865 |
| TAF1A | 7863 |
| H2AZ2 | 7814 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| H4C8 | 10752.0 |
| POLR2K | 10402.0 |
| H2AJ | 9870.0 |
| ACTB | 9643.0 |
| DEK | 9433.0 |
| H3C10 | 9015.0 |
| H3C11 | 8963.0 |
| H4C12 | 8883.0 |
| KAT2B | 8850.0 |
| H4C2 | 8690.0 |
| POLR1C | 8652.0 |
| H3-3A | 8639.0 |
| H2BC13 | 8609.0 |
| H2BC1 | 8383.0 |
| POLR1G | 8105.0 |
| H3C12 | 8052.0 |
| DDX21 | 7989.0 |
| POLR1E | 7865.0 |
| TAF1A | 7863.0 |
| H2AZ2 | 7814.0 |
| H2AC7 | 7754.5 |
| H2BC7 | 7754.5 |
| H4C16 | 7260.0 |
| POLR1A | 7244.0 |
| H2AC8 | 6630.0 |
| POLR1B | 6206.0 |
| H3-3B | 6110.0 |
| H2BC8 | 6087.0 |
| H4C3 | 5935.0 |
| H4C1 | 5864.0 |
| H3C1 | 5598.0 |
| MYO1C | 5390.0 |
| H2BC5 | 5130.0 |
| H4C6 | 4952.0 |
| H3C4 | 4718.0 |
| H2BC3 | 4658.0 |
| H4C13 | 4630.0 |
| H4C11 | 4553.0 |
| SF3B1 | 4515.0 |
| POLR1H | 4220.0 |
| TAF1B | 4095.0 |
| H2BC10 | 3947.0 |
| H4C4 | 3785.0 |
| POLR1D | 3345.0 |
| H2BC17 | 3276.0 |
| POLR2E | 3177.0 |
| BAZ1B | 3050.0 |
| H3C6 | 3009.0 |
| H2AC6 | 2946.0 |
| ERCC6 | 2881.0 |
| H3C8 | 2699.0 |
| H2AC4 | 2379.0 |
| H3C2 | 1438.0 |
| H2BC11 | 1338.0 |
| TAF1D | 1064.0 |
| H2AX | 499.0 |
| POLR1F | 404.0 |
| H2BC15 | 240.0 |
| SMARCA5 | 228.0 |
| TBP | -326.0 |
| H2AZ1 | -360.0 |
| H3C3 | -546.0 |
| H2AC20 | -674.0 |
| POLR2L | -971.0 |
| H2BC6 | -1396.0 |
| H2BC4 | -2094.0 |
| MYBBP1A | -2101.0 |
| H2BC12 | -2115.0 |
| EP300 | -2354.0 |
| TAF1C | -3698.0 |
| POLR2F | -4762.0 |
| H2BC9 | -4907.5 |
| H3C7 | -4907.5 |
| H4C5 | -4941.0 |
| H2BC21 | -5773.0 |
| GSK3B | -6007.0 |
| POLR2H | -6261.0 |
| KAT2A | -6518.0 |
| H2BC26 | -6695.0 |
| H2AC14 | -8606.0 |
| H2BC14 | -8730.0 |
| H4C9 | -9282.0 |
| H2AC18 | -10224.5 |
| H2AC19 | -10224.5 |
REACTOME_PEROXISOMAL_PROTEIN_IMPORT
| 1426 | |
|---|---|
| set | REACTOME_PEROXISOMAL_PROTEIN_IMPORT |
| setSize | 62 |
| pANOVA | 0.00033 |
| s.dist | 0.264 |
| p.adjustANOVA | 0.0118 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| DHRS4 | 10666 |
| ECH1 | 10485 |
| HMGCL | 10105 |
| GSTK1 | 9827 |
| UBC | 9476 |
| PEX12 | 9176 |
| ACOT4 | 9047 |
| HAO2 | 9029 |
| MLYCD | 8832 |
| PEX6 | 8745 |
| HAO1 | 8464 |
| HACL1 | 8415 |
| ACOT8 | 8162 |
| PEX2 | 8021 |
| NUDT19 | 7824 |
| IDE | 7794 |
| PEX13 | 7745 |
| UBB | 7674 |
| PIPOX | 7172 |
| RPS27A | 7120 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| DHRS4 | 10666 |
| ECH1 | 10485 |
| HMGCL | 10105 |
| GSTK1 | 9827 |
| UBC | 9476 |
| PEX12 | 9176 |
| ACOT4 | 9047 |
| HAO2 | 9029 |
| MLYCD | 8832 |
| PEX6 | 8745 |
| HAO1 | 8464 |
| HACL1 | 8415 |
| ACOT8 | 8162 |
| PEX2 | 8021 |
| NUDT19 | 7824 |
| IDE | 7794 |
| PEX13 | 7745 |
| UBB | 7674 |
| PIPOX | 7172 |
| RPS27A | 7120 |
| CRAT | 6730 |
| NUDT7 | 6602 |
| PAOX | 6589 |
| ACOX1 | 6543 |
| ECI2 | 6533 |
| BAAT | 6402 |
| ACOT2 | 6239 |
| SCP2 | 5725 |
| IDH1 | 4950 |
| PEX5 | 4944 |
| PEX10 | 4236 |
| EHHADH | 3858 |
| UBE2D2 | 3677 |
| PHYH | 3490 |
| HSD17B4 | 3290 |
| MPV17 | 3176 |
| UBE2D3 | 2976 |
| DECR2 | 2367 |
| CROT | 2152 |
| GNPAT | 1970 |
| PEX7 | 1735 |
| PEX26 | 1489 |
| EPHX2 | 1272 |
| PEX1 | 693 |
| NOS2 | -416 |
| CAT | -1504 |
| AGPS | -1711 |
| ACOX3 | -2085 |
| AMACR | -2550 |
| DAO | -2721 |
| PEX14 | -3153 |
| UBA52 | -3755 |
| ACAA1 | -3917 |
| LONP2 | -4160 |
| ZFAND6 | -4797 |
| PECR | -5329 |
| UBE2D1 | -5394 |
| TYSND1 | -7009 |
| DDO | -7110 |
| SLC27A2 | -8217 |
| ACOX2 | -8938 |
| AGXT | -10379 |
REACTOME_S_PHASE
| 1110 | |
|---|---|
| set | REACTOME_S_PHASE |
| setSize | 159 |
| pANOVA | 0.000358 |
| s.dist | 0.164 |
| p.adjustANOVA | 0.0125 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| E2F1 | 10764 |
| LIN52 | 10563 |
| CDK4 | 10506 |
| POLE3 | 10464 |
| POLD4 | 10382 |
| PSMD12 | 10325 |
| PSMC6 | 9977 |
| PSMB3 | 9858 |
| UBC | 9476 |
| MCM2 | 9367 |
| RBX1 | 9293 |
| LIN37 | 9132 |
| FEN1 | 9002 |
| GINS2 | 8991 |
| PSME2 | 8685 |
| CDKN1B | 8453 |
| CCNH | 8435 |
| CKS1B | 8430 |
| DNA2 | 8298 |
| PSMB4 | 8180 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| E2F1 | 10764 |
| LIN52 | 10563 |
| CDK4 | 10506 |
| POLE3 | 10464 |
| POLD4 | 10382 |
| PSMD12 | 10325 |
| PSMC6 | 9977 |
| PSMB3 | 9858 |
| UBC | 9476 |
| MCM2 | 9367 |
| RBX1 | 9293 |
| LIN37 | 9132 |
| FEN1 | 9002 |
| GINS2 | 8991 |
| PSME2 | 8685 |
| CDKN1B | 8453 |
| CCNH | 8435 |
| CKS1B | 8430 |
| DNA2 | 8298 |
| PSMB4 | 8180 |
| CDC45 | 7992 |
| PSMD13 | 7901 |
| PSME4 | 7705 |
| UBB | 7674 |
| PSMB2 | 7641 |
| CDC25A | 7593 |
| POLD1 | 7462 |
| PSMB11 | 7359 |
| PSMA6 | 7190 |
| RPS27A | 7120 |
| PSMA1 | 7018 |
| ANAPC11 | 6955 |
| CDK2 | 6939 |
| RBBP4 | 6844 |
| ORC1 | 6803 |
| RAD21 | 6706 |
| PSMD3 | 6672 |
| MCM5 | 6536 |
| ANAPC10 | 5865 |
| PDS5B | 5760 |
| RB1 | 5745 |
| PSMC1 | 5715 |
| MCM4 | 5708 |
| RPA1 | 5651 |
| ESCO2 | 5634 |
| PSMD2 | 5624 |
| PSMA5 | 5362 |
| ANAPC2 | 5346 |
| SMC3 | 5251 |
| PSMA4 | 5246 |
| PSMC5 | 5193 |
| RBL2 | 5110 |
| CDKN1A | 5054 |
| MCM3 | 4832 |
| PCNA | 4821 |
| ANAPC5 | 4671 |
| GINS1 | 4665 |
| ORC2 | 4592 |
| PSMF1 | 4311 |
| CDT1 | 4263 |
| PSMD1 | 4227 |
| PSME3 | 4172 |
| PSMC2 | 4088 |
| E2F5 | 4024 |
| PSMA8 | 3923 |
| PSMA7 | 3903 |
| PSME1 | 3866 |
| PSMA3 | 3850 |
| CABLES1 | 3701 |
| CCNA1 | 3593 |
| SKP1 | 3534 |
| PSMB9 | 3459 |
| TFDP2 | 3339 |
| WAPL | 3291 |
| CCNE2 | 3190 |
| RFC2 | 3136 |
| POLE4 | 3064 |
| CDC27 | 3049 |
| PSMC4 | 3004 |
| PSMC3 | 2960 |
| PRIM1 | 2888 |
| MCM7 | 2717 |
| SEM1 | 2517 |
| CDC26 | 2306 |
| MCM8 | 2177 |
| ORC4 | 1976 |
| ANAPC15 | 1950 |
| CDC23 | 1927 |
| LIN9 | 1238 |
| RPA2 | 1117 |
| RFC4 | 824 |
| CDC16 | 754 |
| PSMD11 | 620 |
| PDS5A | 449 |
| PSMB8 | 447 |
| POLD2 | 347 |
| POLE2 | 60 |
| ORC3 | 36 |
| FZR1 | 16 |
| MCM6 | 2 |
| POLA2 | -22 |
| RFC5 | -81 |
| PSMA2 | -85 |
| ANAPC4 | -310 |
| ORC5 | -617 |
| MNAT1 | -717 |
| GMNN | -730 |
| PSMD14 | -865 |
| GINS4 | -959 |
| PSMD6 | -961 |
| CCND1 | -962 |
| ANAPC1 | -1043 |
| PSMB7 | -1294 |
| UBE2S | -1361 |
| LIG1 | -1478 |
| ESCO1 | -1480 |
| MAX | -1557 |
| TFDP1 | -2156 |
| PSMB10 | -2290 |
| PSMB6 | -2408 |
| CUL1 | -2437 |
| AKT2 | -2480 |
| UBE2C | -2539 |
| AKT1 | -2548 |
| PSMD9 | -2570 |
| MYC | -2593 |
| UBE2E1 | -2647 |
| CDC25B | -3069 |
| STAG1 | -3331 |
| WEE1 | -3415 |
| ORC6 | -3467 |
| CCNA2 | -3495 |
| UBA52 | -3755 |
| ANAPC7 | -3780 |
| RFC1 | -3990 |
| LIN54 | -4429 |
| ANAPC16 | -4502 |
| PSMB5 | -4687 |
| SKP2 | -4745 |
| CDK7 | -4917 |
| RFC3 | -4967 |
| PSMD7 | -5198 |
| PSMD4 | -5337 |
| UBE2D1 | -5394 |
| POLD3 | -5419 |
| AKT3 | -5586 |
| PSMB1 | -5858 |
| GSK3B | -6007 |
| PRIM2 | -6159 |
| E2F4 | -6771 |
| CDCA5 | -7077 |
| CDC6 | -7443 |
| PTK6 | -7557 |
| PSMD8 | -7723 |
| GINS3 | -7990 |
| RPA3 | -8086 |
| POLE | -8297 |
| PSMD5 | -9524 |
| CCNE1 | -9930 |
REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS
| 720 | |
|---|---|
| set | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS |
| setSize | 39 |
| pANOVA | 0.000376 |
| s.dist | -0.329 |
| p.adjustANOVA | 0.0128 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TAS2R41 | -10767 |
| TAS2R20 | -10547 |
| TAS2R42 | -10297 |
| TAS2R43 | -10055 |
| TAS2R14 | -9997 |
| TAS2R10 | -9845 |
| TAS2R39 | -9668 |
| TAS2R8 | -9248 |
| TAS2R40 | -9183 |
| GPRC6A | -9020 |
| TAS2R5 | -8843 |
| GRM2 | -8642 |
| TAS2R13 | -8081 |
| TAS2R16 | -8003 |
| GRM3 | -7150 |
| GABBR2 | -5794 |
| TAS2R38 | -5742 |
| TAS2R30 | -4449 |
| TAS2R50 | -4345 |
| GRM4 | -4317 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TAS2R41 | -10767 |
| TAS2R20 | -10547 |
| TAS2R42 | -10297 |
| TAS2R43 | -10055 |
| TAS2R14 | -9997 |
| TAS2R10 | -9845 |
| TAS2R39 | -9668 |
| TAS2R8 | -9248 |
| TAS2R40 | -9183 |
| GPRC6A | -9020 |
| TAS2R5 | -8843 |
| GRM2 | -8642 |
| TAS2R13 | -8081 |
| TAS2R16 | -8003 |
| GRM3 | -7150 |
| GABBR2 | -5794 |
| TAS2R38 | -5742 |
| TAS2R30 | -4449 |
| TAS2R50 | -4345 |
| GRM4 | -4317 |
| GRM5 | -4030 |
| GRM7 | -3668 |
| TAS2R1 | -3281 |
| GRM6 | -3270 |
| TAS1R1 | -3029 |
| TAS2R46 | -2898 |
| GRM1 | -2242 |
| TAS1R2 | -1566 |
| TAS2R19 | -696 |
| TAS2R9 | 722 |
| TAS1R3 | 971 |
| TAS2R7 | 3323 |
| TAS2R4 | 3808 |
| GRM8 | 4604 |
| GABBR1 | 5617 |
| CASR | 6242 |
| TAS2R3 | 7891 |
| TAS2R60 | 9926 |
| TAS2R31 | 10217 |
REACTOME_M_PHASE
| 1096 | |
|---|---|
| set | REACTOME_M_PHASE |
| setSize | 398 |
| pANOVA | 0.000396 |
| s.dist | 0.103 |
| p.adjustANOVA | 0.0133 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TUBG2 | 10998 |
| H4C8 | 10752 |
| CHMP4C | 10392 |
| CENPQ | 10378 |
| PSMD12 | 10325 |
| DYNC1LI2 | 10216 |
| BANF1 | 10027 |
| USO1 | 9986 |
| PSMC6 | 9977 |
| ESPL1 | 9956 |
| KNTC1 | 9932 |
| H2AJ | 9870 |
| PSMB3 | 9858 |
| TUBG1 | 9820 |
| UBC | 9476 |
| DSN1 | 9391 |
| TUBB6 | 9058 |
| PPP2R5B | 9055 |
| H3C10 | 9015 |
| H3C11 | 8963 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TUBG2 | 10998.0 |
| H4C8 | 10752.0 |
| CHMP4C | 10392.0 |
| CENPQ | 10378.0 |
| PSMD12 | 10325.0 |
| DYNC1LI2 | 10216.0 |
| BANF1 | 10027.0 |
| USO1 | 9986.0 |
| PSMC6 | 9977.0 |
| ESPL1 | 9956.0 |
| KNTC1 | 9932.0 |
| H2AJ | 9870.0 |
| PSMB3 | 9858.0 |
| TUBG1 | 9820.0 |
| UBC | 9476.0 |
| DSN1 | 9391.0 |
| TUBB6 | 9058.0 |
| PPP2R5B | 9055.0 |
| H3C10 | 9015.0 |
| H3C11 | 8963.0 |
| POM121 | 8943.0 |
| ZWINT | 8928.0 |
| LEMD3 | 8915.0 |
| H4C12 | 8883.0 |
| BUB1B | 8870.0 |
| SSNA1 | 8831.0 |
| AURKB | 8795.0 |
| CSNK2B | 8721.0 |
| PPP2R5D | 8711.0 |
| ITGB3BP | 8707.0 |
| H4C2 | 8690.0 |
| PSME2 | 8685.0 |
| H3-3A | 8639.0 |
| H2BC13 | 8609.0 |
| H2BC1 | 8383.0 |
| CLIP1 | 8357.0 |
| TUBAL3 | 8355.0 |
| DYNLL2 | 8325.0 |
| SIRT2 | 8280.0 |
| KIF23 | 8268.0 |
| PSMB4 | 8180.0 |
| NEK9 | 8080.0 |
| H3C12 | 8052.0 |
| TUBB4B | 7956.0 |
| PSMD13 | 7901.0 |
| H2AZ2 | 7814.0 |
| TUBB3 | 7767.0 |
| NUP155 | 7761.0 |
| H2AC7 | 7754.5 |
| H2BC7 | 7754.5 |
| CENPM | 7709.0 |
| PSME4 | 7705.0 |
| CENPL | 7683.0 |
| UBB | 7674.0 |
| PSMB2 | 7641.0 |
| NDC80 | 7594.0 |
| KMT5A | 7432.0 |
| AHCTF1 | 7417.0 |
| LMNA | 7398.0 |
| CCNB1 | 7396.0 |
| PSMB11 | 7359.0 |
| H4C16 | 7260.0 |
| TUBA8 | 7215.0 |
| PSMA6 | 7190.0 |
| BIRC5 | 7158.0 |
| RAB1B | 7123.0 |
| RPS27A | 7120.0 |
| MASTL | 7036.0 |
| PSMA1 | 7018.0 |
| ANAPC11 | 6955.0 |
| SEH1L | 6838.0 |
| NUP35 | 6822.0 |
| TUBB8 | 6817.0 |
| BUB1 | 6792.0 |
| TUBB2B | 6768.0 |
| NCAPG | 6722.0 |
| RAD21 | 6706.0 |
| LBR | 6693.0 |
| NUP85 | 6688.0 |
| PSMD3 | 6672.0 |
| H2AC8 | 6630.0 |
| CENPC | 6615.0 |
| VRK2 | 6403.0 |
| NUP37 | 6306.0 |
| ZW10 | 6123.0 |
| H3-3B | 6110.0 |
| H2BC8 | 6087.0 |
| SKA2 | 6014.0 |
| H4C3 | 5935.0 |
| NUP43 | 5921.0 |
| KNL1 | 5868.0 |
| ANAPC10 | 5865.0 |
| H4C1 | 5864.0 |
| CKAP5 | 5856.0 |
| NEK2 | 5826.0 |
| DCTN2 | 5812.0 |
| B9D2 | 5784.0 |
| CENPT | 5768.0 |
| PDS5B | 5760.0 |
| RB1 | 5745.0 |
| PSMC1 | 5715.0 |
| RAN | 5697.0 |
| CC2D1B | 5682.0 |
| SGO2 | 5675.0 |
| NUP54 | 5644.0 |
| PSMD2 | 5624.0 |
| H3C1 | 5598.0 |
| NCAPD2 | 5528.0 |
| PAFAH1B1 | 5441.0 |
| PSMA5 | 5362.0 |
| PLK1 | 5347.0 |
| ANAPC2 | 5346.0 |
| KIF2C | 5265.0 |
| SMC3 | 5251.0 |
| PSMA4 | 5246.0 |
| CEP70 | 5241.0 |
| PSMC5 | 5193.0 |
| H2BC5 | 5130.0 |
| NUP107 | 5069.0 |
| CEP152 | 5016.0 |
| H4C6 | 4952.0 |
| RCC2 | 4920.0 |
| NUP88 | 4788.0 |
| CDC20 | 4753.0 |
| H3C4 | 4718.0 |
| RPS27 | 4711.0 |
| SPC25 | 4707.0 |
| CSNK2A1 | 4697.0 |
| NUP133 | 4676.0 |
| ANAPC5 | 4671.0 |
| H2BC3 | 4658.0 |
| TUBGCP2 | 4639.0 |
| H4C13 | 4630.0 |
| CEP135 | 4607.0 |
| H4C11 | 4553.0 |
| FBXO5 | 4493.0 |
| KIF18A | 4448.0 |
| MAD2L1 | 4439.0 |
| KPNB1 | 4376.0 |
| NSL1 | 4358.0 |
| PSMF1 | 4311.0 |
| UBE2I | 4265.0 |
| NME7 | 4251.0 |
| PMF1 | 4232.0 |
| PSMD1 | 4227.0 |
| PSME3 | 4172.0 |
| CENPE | 4143.0 |
| CSNK2A2 | 4122.0 |
| PSMC2 | 4088.0 |
| TNPO1 | 4083.0 |
| CENPS | 4026.0 |
| SMC2 | 3987.0 |
| CDCA8 | 3983.0 |
| H2BC10 | 3947.0 |
| PSMA8 | 3923.0 |
| PSMA7 | 3903.0 |
| PSME1 | 3866.0 |
| PSMA3 | 3850.0 |
| H4C4 | 3785.0 |
| NUP205 | 3738.0 |
| MAPRE1 | 3644.0 |
| PRKCB | 3548.0 |
| PRKACA | 3519.0 |
| CEP78 | 3480.0 |
| PSMB9 | 3459.0 |
| RCC1 | 3406.0 |
| PPP2R5C | 3398.0 |
| WAPL | 3291.0 |
| H2BC17 | 3276.0 |
| CENPF | 3253.0 |
| CSNK1D | 3179.0 |
| ACTR1A | 3117.0 |
| SET | 3096.0 |
| CDC27 | 3049.0 |
| H3C6 | 3009.0 |
| PSMC4 | 3004.0 |
| NUF2 | 2983.0 |
| PSMC3 | 2960.0 |
| H2AC6 | 2946.0 |
| NUP42 | 2844.0 |
| HAUS8 | 2809.0 |
| NUP93 | 2792.0 |
| NUP58 | 2703.0 |
| H3C8 | 2699.0 |
| RANBP2 | 2651.0 |
| SEM1 | 2517.0 |
| H2AC4 | 2379.0 |
| CDC26 | 2306.0 |
| PPP2CA | 2292.0 |
| CHMP6 | 2240.0 |
| IST1 | 2232.0 |
| HAUS2 | 2201.0 |
| CHMP4A | 2193.0 |
| CCNB2 | 2043.0 |
| H3-4 | 2030.0 |
| RAB1A | 1997.0 |
| ANAPC15 | 1950.0 |
| CDC23 | 1927.0 |
| BUB3 | 1906.0 |
| CENPJ | 1883.0 |
| CEP250 | 1760.0 |
| SGO1 | 1729.0 |
| CENPK | 1710.0 |
| CHMP3 | 1707.0 |
| HAUS5 | 1481.0 |
| CCP110 | 1440.0 |
| H3C2 | 1438.0 |
| HSP90AA1 | 1355.0 |
| H2BC11 | 1338.0 |
| NCAPH | 1206.0 |
| HAUS3 | 1201.0 |
| PPP2R2A | 1071.0 |
| ANKLE2 | 983.0 |
| CEP63 | 968.0 |
| TUBA4A | 938.0 |
| MZT2A | 915.0 |
| CDC16 | 754.0 |
| YWHAE | 744.0 |
| ENSA | 708.0 |
| TUBA4B | 650.0 |
| NDEL1 | 641.0 |
| SDCCAG8 | 622.0 |
| PSMD11 | 620.0 |
| CNEP1R1 | 520.0 |
| H2AX | 499.0 |
| NEK7 | 461.0 |
| TUBGCP6 | 457.0 |
| PDS5A | 449.0 |
| PSMB8 | 447.0 |
| CHMP7 | 308.0 |
| H2BC15 | 240.0 |
| DYNC1LI1 | 233.0 |
| DCTN3 | 114.0 |
| MIS12 | 15.0 |
| PSMA2 | -85.0 |
| PPP2R5A | -152.0 |
| PCM1 | -170.0 |
| HAUS1 | -189.0 |
| DYNC1I1 | -202.0 |
| ANAPC4 | -310.0 |
| KIF20A | -330.0 |
| NUP98 | -351.0 |
| H2AZ1 | -360.0 |
| DYNC1I2 | -440.0 |
| CHMP2A | -462.0 |
| H3C3 | -546.0 |
| TUBB1 | -584.0 |
| H2AC20 | -674.0 |
| HAUS4 | -693.0 |
| RAB2A | -745.0 |
| CEP41 | -791.0 |
| MAPK1 | -857.0 |
| PSMD14 | -865.0 |
| CENPO | -914.0 |
| PSMD6 | -961.0 |
| NEK6 | -969.0 |
| SPDL1 | -977.0 |
| AKAP9 | -1032.0 |
| ANAPC1 | -1043.0 |
| XPO1 | -1083.0 |
| CHMP4B | -1102.0 |
| CEP72 | -1128.0 |
| PSMB7 | -1294.0 |
| LMNB1 | -1316.0 |
| PTTG1 | -1320.0 |
| BLZF1 | -1356.0 |
| UBE2S | -1361.0 |
| H2BC6 | -1396.0 |
| NDC1 | -1433.0 |
| NUDC | -1567.0 |
| PPP2R2D | -1687.0 |
| NUP188 | -1877.0 |
| YWHAG | -1887.0 |
| SMC4 | -1946.0 |
| CLASP1 | -2048.0 |
| H2BC4 | -2094.0 |
| PPP2R1A | -2107.0 |
| H2BC12 | -2115.0 |
| CEP290 | -2146.0 |
| CENPN | -2163.0 |
| CLASP2 | -2170.0 |
| ZWILCH | -2190.0 |
| GORASP2 | -2197.0 |
| TUBB | -2261.0 |
| PSMB10 | -2290.0 |
| CTDNEP1 | -2338.0 |
| ODF2 | -2377.0 |
| PSMB6 | -2408.0 |
| LPIN2 | -2453.0 |
| MZT1 | -2477.0 |
| PPP2R5E | -2509.0 |
| SUMO1 | -2534.0 |
| UBE2C | -2539.0 |
| PSMD9 | -2570.0 |
| UBE2E1 | -2647.0 |
| SFI1 | -2689.0 |
| NCAPG2 | -2771.0 |
| AAAS | -2839.0 |
| CEP57 | -3092.0 |
| PPP1CC | -3102.0 |
| LEMD2 | -3163.0 |
| PRKCA | -3175.0 |
| PRKAR2B | -3186.0 |
| CHMP2B | -3280.0 |
| GORASP1 | -3300.0 |
| STAG1 | -3331.0 |
| NUP153 | -3416.0 |
| SPAST | -3426.0 |
| SPC24 | -3429.0 |
| NCAPD3 | -3452.0 |
| RAE1 | -3503.0 |
| DYNLL1 | -3541.0 |
| EML4 | -3716.0 |
| UBA52 | -3755.0 |
| ANAPC7 | -3780.0 |
| LPIN1 | -3821.0 |
| ALMS1 | -3856.0 |
| RANGAP1 | -3961.0 |
| POM121C | -4045.0 |
| TUBGCP5 | -4190.0 |
| NEDD1 | -4195.0 |
| PLK4 | -4251.0 |
| TUBA1C | -4357.0 |
| CEP43 | -4402.0 |
| TUBA1B | -4469.0 |
| ANAPC16 | -4502.0 |
| PSMB5 | -4687.0 |
| CEP192 | -4704.0 |
| CNTRL | -4773.0 |
| H2BC9 | -4907.5 |
| H3C7 | -4907.5 |
| H4C5 | -4941.0 |
| VPS4A | -5196.0 |
| PSMD7 | -5198.0 |
| TAOK1 | -5237.0 |
| TUBA3D | -5264.0 |
| INCENP | -5274.0 |
| CEP76 | -5319.0 |
| PSMD4 | -5337.0 |
| UBE2D1 | -5394.0 |
| DCTN1 | -5418.0 |
| MAPK3 | -5444.0 |
| NUP214 | -5472.0 |
| CEP131 | -5479.0 |
| SEC13 | -5670.0 |
| H2BC21 | -5773.0 |
| NDE1 | -5839.0 |
| PSMB1 | -5858.0 |
| VRK1 | -5980.0 |
| MCPH1 | -5981.0 |
| MAD1L1 | -6006.0 |
| DYNC1H1 | -6092.0 |
| CDK1 | -6160.0 |
| GOLGA2 | -6181.0 |
| NUP50 | -6183.0 |
| CENPU | -6349.0 |
| CDK5RAP2 | -6528.0 |
| TMPO | -6633.0 |
| NUP210 | -6637.0 |
| H2BC26 | -6695.0 |
| NUMA1 | -6909.0 |
| SKA1 | -6910.0 |
| MAU2 | -6927.0 |
| KIF2A | -6979.0 |
| CDCA5 | -7077.0 |
| NUP160 | -7169.0 |
| PPP2CB | -7216.0 |
| NUP62 | -7266.0 |
| TUBGCP3 | -7341.0 |
| ARPP19 | -7351.0 |
| PCNT | -7476.0 |
| CSNK1E | -7527.0 |
| TUBB4A | -7633.0 |
| CEP164 | -7712.0 |
| PSMD8 | -7723.0 |
| NCAPH2 | -7762.0 |
| CENPP | -7911.0 |
| NIPBL | -7970.0 |
| TUBGCP4 | -7988.0 |
| TUBA1A | -8056.0 |
| NINL | -8186.0 |
| PPP2R1B | -8245.0 |
| H2AC14 | -8606.0 |
| HAUS6 | -8616.0 |
| CENPH | -8704.0 |
| H2BC14 | -8730.0 |
| MZT2B | -8774.0 |
| KIF2B | -8857.0 |
| LPIN3 | -8997.0 |
| TPR | -9043.0 |
| H4C9 | -9282.0 |
| TUBB2A | -9511.0 |
| PSMD5 | -9524.0 |
| CENPA | -9945.0 |
| TUBA3C | -10220.0 |
| H2AC18 | -10224.5 |
| H2AC19 | -10224.5 |
| TUBA3E | -10574.0 |
REACTOME_G1_S_DNA_DAMAGE_CHECKPOINTS
| 1118 | |
|---|---|
| set | REACTOME_G1_S_DNA_DAMAGE_CHECKPOINTS |
| setSize | 67 |
| pANOVA | 0.000416 |
| s.dist | 0.249 |
| p.adjustANOVA | 0.0137 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| PSMD12 | 10325 |
| PSMC6 | 9977 |
| PSMB3 | 9858 |
| UBC | 9476 |
| PSME2 | 8685 |
| MDM4 | 8496 |
| CDKN1B | 8453 |
| PSMB4 | 8180 |
| TP53 | 8108 |
| PSMD13 | 7901 |
| PSME4 | 7705 |
| UBB | 7674 |
| PSMB2 | 7641 |
| CDC25A | 7593 |
| PSMB11 | 7359 |
| CDKN2A | 7282 |
| PSMA6 | 7190 |
| RPS27A | 7120 |
| PSMA1 | 7018 |
| CDK2 | 6939 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| PSMD12 | 10325 |
| PSMC6 | 9977 |
| PSMB3 | 9858 |
| UBC | 9476 |
| PSME2 | 8685 |
| MDM4 | 8496 |
| CDKN1B | 8453 |
| PSMB4 | 8180 |
| TP53 | 8108 |
| PSMD13 | 7901 |
| PSME4 | 7705 |
| UBB | 7674 |
| PSMB2 | 7641 |
| CDC25A | 7593 |
| PSMB11 | 7359 |
| CDKN2A | 7282 |
| PSMA6 | 7190 |
| RPS27A | 7120 |
| PSMA1 | 7018 |
| CDK2 | 6939 |
| CHEK1 | 6909 |
| PSMD3 | 6672 |
| PSMC1 | 5715 |
| PSMD2 | 5624 |
| PSMA5 | 5362 |
| PSMA4 | 5246 |
| PSMC5 | 5193 |
| CDKN1A | 5054 |
| ATM | 4600 |
| PSMF1 | 4311 |
| PSMD1 | 4227 |
| PSME3 | 4172 |
| PSMC2 | 4088 |
| PSMA8 | 3923 |
| PSMA7 | 3903 |
| PSME1 | 3866 |
| PSMA3 | 3850 |
| CCNA1 | 3593 |
| PSMB9 | 3459 |
| CHEK2 | 3413 |
| CCNE2 | 3190 |
| PSMC4 | 3004 |
| PSMC3 | 2960 |
| SEM1 | 2517 |
| PSMD11 | 620 |
| PCBP4 | 475 |
| PSMB8 | 447 |
| MDM2 | 219 |
| PSMA2 | -85 |
| COP1 | -554 |
| PSMD14 | -865 |
| PSMD6 | -961 |
| PSMB7 | -1294 |
| PHF20 | -1999 |
| PSMB10 | -2290 |
| PSMB6 | -2408 |
| PSMD9 | -2570 |
| CCNA2 | -3495 |
| UBA52 | -3755 |
| PSMB5 | -4687 |
| PSMD7 | -5198 |
| PSMD4 | -5337 |
| PSMB1 | -5858 |
| PSMD8 | -7723 |
| ZNF385A | -8149 |
| PSMD5 | -9524 |
| CCNE1 | -9930 |
Here is the session info with all the versions of packages used.
sessionInfo()## R version 4.3.2 (2023-10-31)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.3 LTS
##
## Matrix products: default
## BLAS: /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so; LAPACK version 3.10.0
##
## locale:
## [1] LC_CTYPE=en_US.UTF-8 LC_NUMERIC=C
## [3] LC_TIME=en_US.UTF-8 LC_COLLATE=en_US.UTF-8
## [5] LC_MONETARY=en_US.UTF-8 LC_MESSAGES=en_US.UTF-8
## [7] LC_PAPER=en_US.UTF-8 LC_NAME=C
## [9] LC_ADDRESS=C LC_TELEPHONE=C
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C
##
## time zone: Etc/UTC
## tzcode source: system (glibc)
##
## attached base packages:
## [1] parallel stats4 stats graphics grDevices utils datasets
## [8] methods base
##
## other attached packages:
## [1] pkgload_1.3.3
## [2] GGally_2.2.0
## [3] ggplot2_3.4.4
## [4] reshape2_1.4.4
## [5] gtools_3.9.5
## [6] tibble_3.2.1
## [7] dplyr_1.1.4
## [8] echarts4r_0.4.5
## [9] png_0.1-8
## [10] gridExtra_2.3
## [11] missMethyl_1.36.0
## [12] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.1
## [13] beeswarm_0.4.0
## [14] kableExtra_1.3.4
## [15] gplots_3.1.3
## [16] mitch_1.15.0
## [17] tictoc_1.2
## [18] HGNChelper_0.8.1
## [19] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [20] IlluminaHumanMethylation450kmanifest_0.4.0
## [21] minfi_1.48.0
## [22] bumphunter_1.44.0
## [23] locfit_1.5-9.8
## [24] iterators_1.0.14
## [25] foreach_1.5.2
## [26] Biostrings_2.70.1
## [27] XVector_0.42.0
## [28] SummarizedExperiment_1.32.0
## [29] Biobase_2.62.0
## [30] MatrixGenerics_1.14.0
## [31] matrixStats_1.2.0
## [32] GenomicRanges_1.54.1
## [33] GenomeInfoDb_1.38.2
## [34] IRanges_2.36.0
## [35] S4Vectors_0.40.2
## [36] BiocGenerics_0.48.1
## [37] eulerr_7.0.0
## [38] limma_3.58.1
##
## loaded via a namespace (and not attached):
## [1] splines_4.3.2 later_1.3.2
## [3] BiocIO_1.12.0 bitops_1.0-7
## [5] filelock_1.0.3 preprocessCore_1.64.0
## [7] XML_3.99-0.16 lifecycle_1.0.4
## [9] lattice_0.22-5 MASS_7.3-60
## [11] base64_2.0.1 scrime_1.3.5
## [13] magrittr_2.0.3 sass_0.4.8
## [15] rmarkdown_2.25 jquerylib_0.1.4
## [17] yaml_2.3.8 httpuv_1.6.13
## [19] doRNG_1.8.6 askpass_1.2.0
## [21] DBI_1.1.3 RColorBrewer_1.1-3
## [23] abind_1.4-5 zlibbioc_1.48.0
## [25] rvest_1.0.3 quadprog_1.5-8
## [27] purrr_1.0.2 RCurl_1.98-1.13
## [29] rappdirs_0.3.3 GenomeInfoDbData_1.2.11
## [31] genefilter_1.84.0 annotate_1.80.0
## [33] svglite_2.1.3 DelayedMatrixStats_1.24.0
## [35] codetools_0.2-19 DelayedArray_0.28.0
## [37] xml2_1.3.6 tidyselect_1.2.0
## [39] beanplot_1.3.1 BiocFileCache_2.10.1
## [41] webshot_0.5.5 illuminaio_0.44.0
## [43] GenomicAlignments_1.38.0 jsonlite_1.8.8
## [45] multtest_2.58.0 ellipsis_0.3.2
## [47] survival_3.5-7 systemfonts_1.0.5
## [49] tools_4.3.2 progress_1.2.3
## [51] Rcpp_1.0.11 glue_1.6.2
## [53] SparseArray_1.2.2 xfun_0.41
## [55] HDF5Array_1.30.0 withr_2.5.2
## [57] fastmap_1.1.1 rhdf5filters_1.14.1
## [59] fansi_1.0.6 openssl_2.1.1
## [61] caTools_1.18.2 digest_0.6.33
## [63] R6_2.5.1 mime_0.12
## [65] colorspace_2.1-0 biomaRt_2.58.0
## [67] RSQLite_2.3.4 utf8_1.2.4
## [69] tidyr_1.3.0 generics_0.1.3
## [71] data.table_1.14.10 rtracklayer_1.62.0
## [73] prettyunits_1.2.0 httr_1.4.7
## [75] htmlwidgets_1.6.4 S4Arrays_1.2.0
## [77] ggstats_0.5.1 pkgconfig_2.0.3
## [79] gtable_0.3.4 blob_1.2.4
## [81] siggenes_1.76.0 htmltools_0.5.7
## [83] scales_1.3.0 rstudioapi_0.15.0
## [85] knitr_1.45 tzdb_0.4.0
## [87] rjson_0.2.21 nlme_3.1-163
## [89] curl_5.2.0 org.Hs.eg.db_3.18.0
## [91] cachem_1.0.8 rhdf5_2.46.1
## [93] stringr_1.5.1 KernSmooth_2.23-22
## [95] AnnotationDbi_1.64.1 restfulr_0.0.15
## [97] GEOquery_2.70.0 pillar_1.9.0
## [99] grid_4.3.2 reshape_0.8.9
## [101] vctrs_0.6.5 promises_1.2.1
## [103] dbplyr_2.4.0 xtable_1.8-4
## [105] evaluate_0.23 readr_2.1.4
## [107] GenomicFeatures_1.54.1 cli_3.6.2
## [109] compiler_4.3.2 Rsamtools_2.18.0
## [111] rlang_1.1.2 crayon_1.5.2
## [113] rngtools_1.5.2 nor1mix_1.3-2
## [115] mclust_6.0.1 plyr_1.8.9
## [117] stringi_1.8.3 viridisLite_0.4.2
## [119] BiocParallel_1.36.0 munsell_0.5.0
## [121] Matrix_1.6-1.1 hms_1.1.3
## [123] sparseMatrixStats_1.14.0 bit64_4.0.5
## [125] Rhdf5lib_1.24.1 KEGGREST_1.42.0
## [127] statmod_1.5.0 shiny_1.8.0
## [129] highr_0.10 memoise_2.0.1
## [131] bslib_0.6.1 bit_4.0.5END of report