Mitch Report

date generated: 2024-01-18

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch

	x
A1BG	0.0020388
A1BG-AS1	0.0029418
A1CF	-0.0015391
A2M	-0.0004251
A2M-AS1	0.0057066
A2ML1	0.0000406

Here are some metrics about the input data profile:

Profiling data metrics

	Profile metrics
num_genesets	1654
num_genes_in_profile	22007
duplicated_genes_present	0
num_profile_genes_in_sets	10383
num_profile_genes_not_in_sets	11624

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets: c2.cp.reactome.v2023.1.Hs.symbols.gmt

Gene set metrics

	Gene sets metrics
num_genesets	1654
num_genesets_excluded	365
num_genesets_included	1289

Differential pathway expression

Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

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## in kable. kableExtra can customize either HTML or LaTeX outputs. See
## https://haozhu233.github.io/kableExtra/ for details.

set	setSize	pANOVA	s.dist	p.adjustANOVA
REACTOME TRANSLATION	278	4.49e-21	-0.328	7.37e-18
REACTOME METABOLISM OF RNA	675	3.88e-19	-0.202	3.18e-16
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	105	7.75e-16	-0.455	3.99e-13
REACTOME EUKARYOTIC TRANSLATION INITIATION	110	9.72e-16	-0.443	3.99e-13
REACTOME EUKARYOTIC TRANSLATION ELONGATION	87	2.36e-14	-0.473	7.76e-12
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY	94	1.44e-13	-0.441	3.93e-11
REACTOME INFLUENZA INFECTION	149	1.92e-13	-0.349	4.50e-11
REACTOME RRNA PROCESSING	192	1.24e-12	-0.297	2.54e-10
REACTOME NONSENSE MEDIATED DECAY NMD	107	2.43e-12	-0.392	4.43e-10
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS	161	1.20e-10	-0.294	1.97e-08
REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION	84	2.49e-10	-0.399	3.70e-08
REACTOME SELENOAMINO ACID METABOLISM	108	2.71e-10	-0.352	3.70e-08
REACTOME RNA POLYMERASE I PROMOTER ESCAPE	83	2.53e-09	-0.378	3.11e-07
REACTOME CELLULAR RESPONSE TO STARVATION	147	2.65e-09	-0.284	3.11e-07
REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION	100	3.83e-09	-0.341	4.19e-07
REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION	60	4.19e-09	-0.438	4.30e-07
REACTOME CELLULAR RESPONSES TO STIMULI	779	5.53e-09	-0.123	5.34e-07
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS	121	1.02e-08	-0.301	9.18e-07
REACTOME DNA REPLICATION PRE INITIATION	150	1.06e-08	-0.271	9.18e-07
REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION	62	1.29e-08	-0.418	9.83e-07
REACTOME MEIOTIC RECOMBINATION	80	1.30e-08	-0.368	9.83e-07
REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3	59	1.32e-08	-0.428	9.83e-07
REACTOME INFECTIOUS DISEASE	910	1.40e-08	-0.111	9.99e-07
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	53	4.23e-08	-0.435	2.90e-06
REACTOME DNA METHYLATION	58	6.43e-08	-0.410	4.22e-06
REACTOME SIGNALING BY ROBO RECEPTORS	206	7.05e-08	-0.218	4.45e-06
REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP	104	7.62e-08	-0.305	4.63e-06
REACTOME PRC2 METHYLATES HISTONES AND DNA	65	9.02e-08	-0.383	5.15e-06
REACTOME MITOCHONDRIAL TRANSLATION	93	9.10e-08	-0.321	5.15e-06
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY	33	1.01e-07	-0.535	5.53e-06
REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION	98	1.10e-07	-0.310	5.82e-06
REACTOME DNA REPLICATION	178	1.31e-07	-0.229	6.73e-06
REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	66	2.70e-07	-0.366	1.34e-05
REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS	113	3.00e-07	-0.279	1.45e-05
REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS	100	3.74e-07	-0.294	1.75e-05
REACTOME DISEASES OF PROGRAMMED CELL DEATH	96	4.09e-07	-0.299	1.87e-05
REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE	63	4.98e-07	-0.366	2.21e-05
REACTOME CONDENSATION OF PROPHASE CHROMOSOMES	66	6.18e-07	-0.355	2.67e-05
REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS	83	7.01e-07	-0.315	2.91e-05
REACTOME RNA POLYMERASE I TRANSCRIPTION	102	7.09e-07	-0.284	2.91e-05
REACTOME G2 M CHECKPOINTS	162	8.94e-07	-0.224	3.58e-05
REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY	46	9.30e-07	-0.418	3.64e-05
REACTOME REPRODUCTION	136	1.12e-06	-0.242	4.23e-05
REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE	52	1.13e-06	-0.390	4.23e-05
REACTOME HDACS DEACETYLATE HISTONES	85	1.24e-06	-0.304	4.53e-05
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION	138	1.27e-06	-0.239	4.55e-05
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	263	1.31e-06	-0.173	4.58e-05
REACTOME HATS ACETYLATE HISTONES	129	1.95e-06	-0.243	6.55e-05
REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX	85	1.96e-06	-0.298	6.55e-05
REACTOME HCMV LATE EVENTS	110	3.26e-06	-0.257	1.07e-04

---

Results (complete table)

Click HERE to show results for all gene sets

Complete results

set	setSize	pANOVA	s.dist	p.adjustANOVA
REACTOME TRANSLATION	278	4.49e-21	-3.28e-01	7.37e-18
REACTOME METABOLISM OF RNA	675	3.88e-19	-2.02e-01	3.18e-16
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	105	7.75e-16	-4.55e-01	3.99e-13
REACTOME EUKARYOTIC TRANSLATION INITIATION	110	9.72e-16	-4.43e-01	3.99e-13
REACTOME EUKARYOTIC TRANSLATION ELONGATION	87	2.36e-14	-4.73e-01	7.76e-12
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY	94	1.44e-13	-4.41e-01	3.93e-11
REACTOME INFLUENZA INFECTION	149	1.92e-13	-3.49e-01	4.50e-11
REACTOME RRNA PROCESSING	192	1.24e-12	-2.97e-01	2.54e-10
REACTOME NONSENSE MEDIATED DECAY NMD	107	2.43e-12	-3.92e-01	4.43e-10
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS	161	1.20e-10	-2.94e-01	1.97e-08
REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION	84	2.49e-10	-3.99e-01	3.70e-08
REACTOME SELENOAMINO ACID METABOLISM	108	2.71e-10	-3.52e-01	3.70e-08
REACTOME RNA POLYMERASE I PROMOTER ESCAPE	83	2.53e-09	-3.78e-01	3.11e-07
REACTOME CELLULAR RESPONSE TO STARVATION	147	2.65e-09	-2.84e-01	3.11e-07
REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION	100	3.83e-09	-3.41e-01	4.19e-07
REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION	60	4.19e-09	-4.38e-01	4.30e-07
REACTOME CELLULAR RESPONSES TO STIMULI	779	5.53e-09	-1.23e-01	5.34e-07
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS	121	1.02e-08	-3.01e-01	9.18e-07
REACTOME DNA REPLICATION PRE INITIATION	150	1.06e-08	-2.71e-01	9.18e-07
REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION	62	1.29e-08	-4.18e-01	9.83e-07
REACTOME MEIOTIC RECOMBINATION	80	1.30e-08	-3.68e-01	9.83e-07
REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3	59	1.32e-08	-4.28e-01	9.83e-07
REACTOME INFECTIOUS DISEASE	910	1.40e-08	-1.11e-01	9.99e-07
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	53	4.23e-08	-4.35e-01	2.90e-06
REACTOME DNA METHYLATION	58	6.43e-08	-4.10e-01	4.22e-06
REACTOME SIGNALING BY ROBO RECEPTORS	206	7.05e-08	-2.18e-01	4.45e-06
REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP	104	7.62e-08	-3.05e-01	4.63e-06
REACTOME PRC2 METHYLATES HISTONES AND DNA	65	9.02e-08	-3.83e-01	5.15e-06
REACTOME MITOCHONDRIAL TRANSLATION	93	9.10e-08	-3.21e-01	5.15e-06
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY	33	1.01e-07	-5.35e-01	5.53e-06
REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION	98	1.10e-07	-3.10e-01	5.82e-06
REACTOME DNA REPLICATION	178	1.31e-07	-2.29e-01	6.73e-06
REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	66	2.70e-07	-3.66e-01	1.34e-05
REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS	113	3.00e-07	-2.79e-01	1.45e-05
REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS	100	3.74e-07	-2.94e-01	1.75e-05
REACTOME DISEASES OF PROGRAMMED CELL DEATH	96	4.09e-07	-2.99e-01	1.87e-05
REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE	63	4.98e-07	-3.66e-01	2.21e-05
REACTOME CONDENSATION OF PROPHASE CHROMOSOMES	66	6.18e-07	-3.55e-01	2.67e-05
REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS	83	7.01e-07	-3.15e-01	2.91e-05
REACTOME RNA POLYMERASE I TRANSCRIPTION	102	7.09e-07	-2.84e-01	2.91e-05
REACTOME G2 M CHECKPOINTS	162	8.94e-07	-2.24e-01	3.58e-05
REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY	46	9.30e-07	-4.18e-01	3.64e-05
REACTOME REPRODUCTION	136	1.12e-06	-2.42e-01	4.23e-05
REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE	52	1.13e-06	-3.90e-01	4.23e-05
REACTOME HDACS DEACETYLATE HISTONES	85	1.24e-06	-3.04e-01	4.53e-05
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION	138	1.27e-06	-2.39e-01	4.55e-05
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	263	1.31e-06	-1.73e-01	4.58e-05
REACTOME HATS ACETYLATE HISTONES	129	1.95e-06	-2.43e-01	6.55e-05
REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX	85	1.96e-06	-2.98e-01	6.55e-05
REACTOME HCMV LATE EVENTS	110	3.26e-06	-2.57e-01	1.07e-04
REACTOME RHO GTPASES ACTIVATE PKNS	86	4.52e-06	-2.86e-01	1.45e-04
REACTOME OXIDATIVE STRESS INDUCED SENESCENCE	118	5.28e-06	-2.43e-01	1.67e-04
REACTOME PROCESSING OF DNA DOUBLE STRAND BREAK ENDS	93	5.75e-06	-2.72e-01	1.78e-04
REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION	68	6.47e-06	-3.16e-01	1.97e-04
REACTOME CELL CYCLE CHECKPOINTS	284	7.79e-06	-1.54e-01	2.32e-04
REACTOME MEIOSIS	110	8.02e-06	-2.46e-01	2.35e-04
REACTOME UB SPECIFIC PROCESSING PROTEASES	187	9.93e-06	-1.87e-01	2.86e-04
REACTOME G2 M DNA DAMAGE CHECKPOINT	90	1.06e-05	-2.69e-01	3.01e-04
REACTOME SARS COV 1 HOST INTERACTIONS	92	1.11e-05	-2.65e-01	3.09e-04
REACTOME DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE	76	1.41e-05	-2.88e-01	3.85e-04
REACTOME AMYLOID FIBER FORMATION	102	1.78e-05	-2.46e-01	4.80e-04
REACTOME BASE EXCISION REPAIR AP SITE FORMATION	59	2.19e-05	-3.19e-01	5.79e-04
REACTOME ESTROGEN DEPENDENT GENE EXPRESSION	140	2.75e-05	-2.05e-01	7.18e-04
REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION	90	3.51e-05	-2.52e-01	9.00e-04
REACTOME CHROMOSOME MAINTENANCE	130	3.59e-05	-2.10e-01	9.07e-04
REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION	35	3.90e-05	-4.02e-01	9.71e-04
REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	111	3.99e-05	-2.26e-01	9.77e-04
REACTOME CELL CYCLE	666	4.13e-05	-9.31e-02	9.97e-04
REACTOME DEUBIQUITINATION	260	4.21e-05	-1.48e-01	9.99e-04
REACTOME TELOMERE MAINTENANCE	106	4.26e-05	-2.30e-01	9.99e-04
REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT	222	5.06e-05	-1.58e-01	1.17e-03
REACTOME HOMOLOGY DIRECTED REPAIR	132	5.73e-05	-2.03e-01	1.31e-03
REACTOME MITOTIC PROPHASE	134	5.94e-05	-2.01e-01	1.34e-03
REACTOME CELLULAR SENESCENCE	189	6.26e-05	-1.69e-01	1.39e-03
REACTOME HCMV EARLY EVENTS	128	7.45e-05	-2.03e-01	1.63e-03
REACTOME MRNA SPLICING	197	7.70e-05	-1.63e-01	1.66e-03
REACTOME PRE NOTCH EXPRESSION AND PROCESSING	112	7.89e-05	-2.16e-01	1.68e-03
REACTOME CELL CYCLE MITOTIC	539	8.14e-05	-9.92e-02	1.71e-03
REACTOME MEIOTIC SYNAPSIS	73	1.24e-04	-2.60e-01	2.58e-03
REACTOME SIGNALING BY NOTCH	234	1.35e-04	-1.45e-01	2.77e-03
REACTOME SARS COV 2 HOST INTERACTIONS	191	2.00e-04	-1.56e-01	4.05e-03
REACTOME M PHASE	398	2.14e-04	-1.08e-01	4.28e-03
REACTOME GENE SILENCING BY RNA	133	2.26e-04	-1.85e-01	4.47e-03
REACTOME RESPIRATORY ELECTRON TRANSPORT	90	2.55e-04	-2.23e-01	4.92e-03
REACTOME DNA DOUBLE STRAND BREAK RESPONSE	74	2.55e-04	-2.46e-01	4.92e-03
REACTOME ESR MEDIATED SIGNALING	210	2.70e-04	-1.46e-01	5.16e-03
REACTOME RMTS METHYLATE HISTONE ARGININES	72	3.03e-04	-2.46e-01	5.72e-03
REACTOME SARS COV 1 INFECTION	136	3.20e-04	-1.79e-01	5.96e-03
REACTOME HCMV INFECTION	152	3.85e-04	-1.67e-01	7.10e-03
REACTOME BASE EXCISION REPAIR	87	3.96e-04	-2.20e-01	7.22e-03
REACTOME BETA DEFENSINS	27	4.42e-04	-3.91e-01	7.97e-03
REACTOME UCH PROTEINASES	99	4.47e-04	-2.04e-01	7.99e-03
REACTOME NONHOMOLOGOUS END JOINING NHEJ	64	5.05e-04	-2.51e-01	8.92e-03
REACTOME DNA REPAIR	321	5.28e-04	-1.13e-01	9.23e-03
REACTOME EXTRACELLULAR MATRIX ORGANIZATION	291	5.63e-04	1.18e-01	9.72e-03
REACTOME INTERLEUKIN 12 SIGNALING	43	5.68e-04	-3.04e-01	9.72e-03
REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION	89	6.25e-04	-2.10e-01	1.05e-02
REACTOME RHO GTPASE EFFECTORS	305	6.30e-04	-1.14e-01	1.05e-02
REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	353	8.40e-04	-1.03e-01	1.39e-02
REACTOME DNA DOUBLE STRAND BREAK REPAIR	162	9.84e-04	-1.50e-01	1.62e-02
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX3	94	1.08e-03	-1.95e-01	1.76e-02
REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21	59	1.11e-03	-2.45e-01	1.79e-02
REACTOME RNA POLYMERASE II TRANSCRIPTION	1336	1.18e-03	-5.29e-02	1.87e-02
REACTOME INTERLEUKIN 12 FAMILY SIGNALING	53	1.21e-03	-2.57e-01	1.90e-02
REACTOME SIGNALING BY WNT	318	1.22e-03	-1.05e-01	1.91e-02
REACTOME MAPK6 MAPK4 SIGNALING	91	1.35e-03	-1.94e-01	2.08e-02
REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	134	1.35e-03	1.60e-01	2.08e-02
REACTOME REGULATION OF RUNX3 EXPRESSION AND ACTIVITY	54	1.53e-03	-2.49e-01	2.32e-02
REACTOME DEVELOPMENTAL BIOLOGY	1115	1.95e-03	-5.50e-02	2.94e-02
REACTOME PROTEIN UBIQUITINATION	76	2.60e-03	-2.00e-01	3.88e-02
REACTOME DAP12 INTERACTIONS	37	2.64e-03	-2.86e-01	3.91e-02
REACTOME ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES	59	2.78e-03	2.25e-01	4.07e-02
REACTOME DAP12 SIGNALING	27	2.88e-03	-3.31e-01	4.18e-02
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM	688	3.01e-03	-6.63e-02	4.33e-02
REACTOME SIGNALING BY INTERLEUKINS	444	3.04e-03	-8.20e-02	4.34e-02
REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT	159	3.16e-03	-1.36e-01	4.47e-02
REACTOME E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS	58	3.28e-03	-2.23e-01	4.60e-02
REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS	60	3.47e-03	-2.18e-01	4.82e-02
REACTOME NEURONAL SYSTEM	388	3.49e-03	8.64e-02	4.82e-02
REACTOME SARS COV INFECTIONS	392	3.71e-03	-8.54e-02	5.07e-02
REACTOME DEFENSINS	33	3.87e-03	-2.91e-01	5.25e-02
REACTOME SIGNALING BY GPCR	673	4.33e-03	6.45e-02	5.82e-02
REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	86	4.58e-03	-1.77e-01	6.11e-02
REACTOME NERVOUS SYSTEM DEVELOPMENT	552	4.64e-03	-7.05e-02	6.15e-02
REACTOME COLLAGEN FORMATION	88	4.83e-03	1.74e-01	6.34e-02
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1	229	4.98e-03	-1.08e-01	6.48e-02
REACTOME OLFACTORY SIGNALING PATHWAY	348	5.12e-03	-8.73e-02	6.62e-02
REACTOME SARS COV 2 INFECTION	281	5.35e-03	-9.65e-02	6.86e-02
REACTOME NEGATIVE REGULATION OF NOTCH4 SIGNALING	53	5.51e-03	-2.20e-01	7.01e-02
REACTOME GLUCURONIDATION	23	5.70e-03	-3.33e-01	7.20e-02
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION	1356	5.87e-03	-4.46e-02	7.36e-02
REACTOME CHROMATIN MODIFYING ENZYMES	252	6.51e-03	-9.95e-02	8.09e-02
REACTOME METALLOPROTEASE DUBS	36	7.46e-03	-2.58e-01	9.18e-02
REACTOME TCR SIGNALING	113	7.50e-03	-1.46e-01	9.18e-02
REACTOME SIGNALING BY NOTCH4	80	7.60e-03	-1.73e-01	9.25e-02
REACTOME NGF STIMULATED TRANSCRIPTION	38	7.94e-03	-2.49e-01	9.58e-02
REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL	58	8.11e-03	-2.01e-01	9.72e-02
REACTOME ADAPTIVE IMMUNE SYSTEM	729	8.33e-03	-5.74e-02	9.91e-02
REACTOME FLT3 SIGNALING THROUGH SRC FAMILY KINASES	6	8.43e-03	-6.21e-01	9.96e-02
REACTOME SIGNALING BY NUCLEAR RECEPTORS	283	8.78e-03	-9.05e-02	1.03e-01
REACTOME STABILIZATION OF P53	56	9.48e-03	-2.00e-01	1.10e-01
REACTOME FLT3 SIGNALING BY CBL MUTANTS	7	9.64e-03	-5.65e-01	1.11e-01
REACTOME PROTEIN LOCALIZATION	153	9.84e-03	-1.21e-01	1.13e-01
REACTOME NUCLEAR EVENTS MEDIATED BY NFE2L2	77	1.03e-02	-1.69e-01	1.17e-01
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	122	1.11e-02	-1.33e-01	1.26e-01
REACTOME PARACETAMOL ADME	26	1.15e-02	2.86e-01	1.29e-01
REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION	145	1.16e-02	-1.21e-01	1.30e-01
REACTOME COMPLEX I BIOGENESIS	49	1.22e-02	-2.07e-01	1.34e-01
REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	22	1.22e-02	3.09e-01	1.34e-01
REACTOME S PHASE	159	1.23e-02	-1.15e-01	1.34e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	11	1.24e-02	-4.36e-01	1.34e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION TERMINATION	30	1.28e-02	-2.63e-01	1.38e-01
REACTOME DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING	61	1.28e-02	-1.84e-01	1.38e-01
REACTOME CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY	84	1.33e-02	-1.56e-01	1.41e-01
REACTOME SIGNALING BY EGFR IN CANCER	25	1.34e-02	-2.86e-01	1.41e-01
REACTOME POTASSIUM CHANNELS	102	1.36e-02	1.41e-01	1.42e-01
REACTOME ORC1 REMOVAL FROM CHROMATIN	70	1.36e-02	-1.70e-01	1.42e-01
REACTOME CONDENSATION OF PROMETAPHASE CHROMOSOMES	11	1.36e-02	-4.29e-01	1.42e-01
REACTOME TERMINATION OF TRANSLESION DNA SYNTHESIS	32	1.38e-02	-2.52e-01	1.42e-01
REACTOME REGULATION OF SIGNALING BY CBL	22	1.42e-02	-3.02e-01	1.46e-01
REACTOME DAG AND IP3 SIGNALING	40	1.43e-02	2.24e-01	1.46e-01
REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS	312	1.54e-02	7.97e-02	1.56e-01
REACTOME AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA	54	1.57e-02	-1.90e-01	1.58e-01
REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	80	1.60e-02	-1.56e-01	1.59e-01
REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	101	1.62e-02	1.39e-01	1.59e-01
REACTOME APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS	87	1.63e-02	-1.49e-01	1.59e-01
REACTOME INTERLEUKIN 7 SIGNALING	31	1.63e-02	-2.49e-01	1.59e-01
REACTOME INTEGRATION OF ENERGY METABOLISM	105	1.63e-02	1.36e-01	1.59e-01
REACTOME NEGATIVE REGULATION OF FLT3	15	1.69e-02	-3.56e-01	1.63e-01
REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	14	1.69e-02	3.69e-01	1.63e-01
REACTOME PROGRAMMED CELL DEATH	204	1.75e-02	-9.65e-02	1.67e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE	8	1.77e-02	4.84e-01	1.67e-01
REACTOME G1 S DNA DAMAGE CHECKPOINTS	67	1.77e-02	-1.67e-01	1.67e-01
REACTOME FASL CD95L SIGNALING	5	1.77e-02	-6.12e-01	1.67e-01
REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS	8	1.79e-02	4.83e-01	1.68e-01
REACTOME TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE	39	1.84e-02	-2.18e-01	1.70e-01
REACTOME ONCOGENE INDUCED SENESCENCE	35	1.85e-02	-2.30e-01	1.70e-01
REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM	23	1.86e-02	-2.84e-01	1.70e-01
REACTOME RIPK1 MEDIATED REGULATED NECROSIS	30	1.86e-02	-2.48e-01	1.70e-01
REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	28	1.86e-02	-2.57e-01	1.70e-01
REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX	21	1.88e-02	-2.96e-01	1.71e-01
REACTOME METABOLISM OF CARBOHYDRATES	279	1.93e-02	8.14e-02	1.74e-01
REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT	236	1.95e-02	8.83e-02	1.74e-01
REACTOME VOLTAGE GATED POTASSIUM CHANNELS	42	1.95e-02	2.08e-01	1.74e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS	14	1.97e-02	3.60e-01	1.75e-01
REACTOME UPTAKE OF DIETARY COBALAMINS INTO ENTEROCYTES	9	2.01e-02	4.47e-01	1.78e-01
REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	54	2.03e-02	-1.83e-01	1.78e-01
REACTOME MRNA SPLICING MINOR PATHWAY	49	2.06e-02	-1.91e-01	1.80e-01
REACTOME CELLULAR RESPONSE TO HYPOXIA	74	2.07e-02	-1.56e-01	1.80e-01
REACTOME MUSCLE CONTRACTION	197	2.12e-02	9.52e-02	1.83e-01
REACTOME ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY	5	2.14e-02	-5.94e-01	1.84e-01
REACTOME FLT3 SIGNALING	38	2.25e-02	-2.14e-01	1.92e-01
REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING	34	2.26e-02	-2.26e-01	1.92e-01
REACTOME NEDDYLATION	235	2.30e-02	-8.61e-02	1.95e-01
REACTOME FORMATION OF TC NER PRE INCISION COMPLEX	51	2.32e-02	-1.84e-01	1.95e-01
REACTOME HIV INFECTION	223	2.34e-02	-8.81e-02	1.96e-01
REACTOME G PROTEIN MEDIATED EVENTS	53	2.56e-02	1.77e-01	2.13e-01
REACTOME ADRENOCEPTORS	9	2.58e-02	-4.29e-01	2.14e-01
REACTOME DNA DAMAGE BYPASS	47	2.69e-02	-1.87e-01	2.21e-01
REACTOME STRIATED MUSCLE CONTRACTION	35	2.70e-02	2.16e-01	2.21e-01
REACTOME SYNTHESIS OF DNA	119	2.71e-02	-1.17e-01	2.21e-01
REACTOME NUCLEOTIDE EXCISION REPAIR	107	2.72e-02	-1.24e-01	2.21e-01
REACTOME CROSSLINKING OF COLLAGEN FIBRILS	16	2.76e-02	3.18e-01	2.23e-01
REACTOME TNFR2 NON CANONICAL NF KB PATHWAY	96	2.79e-02	-1.30e-01	2.24e-01
REACTOME ACTIVATION OF C3 AND C5	6	2.83e-02	5.17e-01	2.27e-01
REACTOME FGFR3 LIGAND BINDING AND ACTIVATION	12	2.84e-02	3.65e-01	2.27e-01
REACTOME SIGNALING BY THE B CELL RECEPTOR BCR	106	2.91e-02	-1.23e-01	2.31e-01
REACTOME STAT5 ACTIVATION	7	2.93e-02	-4.76e-01	2.32e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE GIP	12	2.97e-02	-3.62e-01	2.33e-01
REACTOME DNA DAMAGE RECOGNITION IN GG NER	36	3.00e-02	-2.09e-01	2.34e-01
REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	16	3.03e-02	-3.13e-01	2.34e-01
REACTOME ABC TRANSPORTER DISORDERS	76	3.05e-02	-1.44e-01	2.34e-01
REACTOME SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE	91	3.06e-02	-1.31e-01	2.34e-01
REACTOME SEPARATION OF SISTER CHROMATIDS	184	3.06e-02	-9.24e-02	2.34e-01
REACTOME HDR THROUGH SINGLE STRAND ANNEALING SSA	37	3.07e-02	-2.05e-01	2.34e-01
REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE	11	3.12e-02	3.75e-01	2.37e-01
REACTOME DUAL INCISION IN TC NER	63	3.13e-02	-1.57e-01	2.37e-01
REACTOME DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX	83	3.26e-02	-1.36e-01	2.46e-01
REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	38	3.37e-02	1.99e-01	2.52e-01
REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	26	3.37e-02	2.41e-01	2.52e-01
REACTOME THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT	77	3.43e-02	-1.39e-01	2.55e-01
REACTOME TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER	76	3.44e-02	-1.40e-01	2.55e-01
REACTOME CA DEPENDENT EVENTS	36	3.50e-02	2.03e-01	2.57e-01
REACTOME HDL CLEARANCE	5	3.50e-02	5.44e-01	2.57e-01
REACTOME INNATE IMMUNE SYSTEM	1002	3.52e-02	-3.93e-02	2.57e-01
REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY	72	3.54e-02	-1.43e-01	2.57e-01
REACTOME MITOTIC METAPHASE AND ANAPHASE	228	3.62e-02	-8.05e-02	2.62e-01
REACTOME G ALPHA I SIGNALLING EVENTS	304	3.68e-02	6.96e-02	2.65e-01
REACTOME SCAVENGING BY CLASS A RECEPTORS	19	3.77e-02	-2.75e-01	2.71e-01
REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION	62	3.87e-02	-1.52e-01	2.76e-01
REACTOME DEGRADATION OF DVL	56	3.89e-02	-1.60e-01	2.76e-01
REACTOME HEDGEHOG LIGAND BIOGENESIS	64	3.91e-02	-1.49e-01	2.76e-01
REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	15	3.94e-02	3.07e-01	2.76e-01
REACTOME EICOSANOIDS	12	3.94e-02	-3.43e-01	2.76e-01
REACTOME STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS	10	3.99e-02	-3.75e-01	2.77e-01
REACTOME ANTIMICROBIAL PEPTIDES	76	3.99e-02	-1.36e-01	2.77e-01
REACTOME CAMK IV MEDIATED PHOSPHORYLATION OF CREB	10	4.00e-02	3.75e-01	2.77e-01
REACTOME GPCR LIGAND BINDING	444	4.03e-02	5.68e-02	2.78e-01
REACTOME KERATINIZATION	210	4.07e-02	8.19e-02	2.80e-01
REACTOME TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA	17	4.11e-02	-2.86e-01	2.81e-01
REACTOME DEGRADATION OF AXIN	54	4.14e-02	-1.60e-01	2.82e-01
REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	59	4.30e-02	-1.52e-01	2.91e-01
REACTOME NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION	193	4.31e-02	8.44e-02	2.91e-01
REACTOME GAB1 SIGNALOSOME	17	4.37e-02	-2.83e-01	2.94e-01
REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET	8	4.43e-02	-4.11e-01	2.97e-01
REACTOME INTERLEUKIN 36 PATHWAY	7	4.51e-02	4.37e-01	3.01e-01
REACTOME COLLAGEN DEGRADATION	61	4.58e-02	1.48e-01	3.04e-01
REACTOME INTERLEUKIN 1 SIGNALING	110	4.59e-02	-1.10e-01	3.04e-01
REACTOME SNRNP ASSEMBLY	53	4.63e-02	-1.58e-01	3.05e-01
REACTOME TYPE I HEMIDESMOSOME ASSEMBLY	11	4.66e-02	3.47e-01	3.05e-01
REACTOME DEGRADATION OF GLI1 BY THE PROTEASOME	59	4.66e-02	-1.50e-01	3.05e-01
REACTOME HOST INTERACTIONS OF HIV FACTORS	127	4.75e-02	-1.02e-01	3.08e-01
REACTOME CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS	19	4.75e-02	-2.63e-01	3.08e-01
REACTOME COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES	65	4.76e-02	1.42e-01	3.08e-01
REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX	39	4.84e-02	-1.83e-01	3.10e-01
REACTOME APOPTOSIS	173	4.84e-02	-8.70e-02	3.10e-01
REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	98	4.85e-02	-1.15e-01	3.10e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	28	4.93e-02	-2.15e-01	3.14e-01
REACTOME FLT3 SIGNALING IN DISEASE	28	4.95e-02	-2.14e-01	3.14e-01
REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	73	4.98e-02	-1.33e-01	3.15e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS	9	5.08e-02	3.76e-01	3.19e-01
REACTOME RUNX3 REGULATES WNT SIGNALING	8	5.08e-02	-3.99e-01	3.19e-01
REACTOME RNA POLYMERASE II TRANSCRIBES SNRNA GENES	77	5.12e-02	-1.29e-01	3.20e-01
REACTOME FRUCTOSE CATABOLISM	5	5.18e-02	5.02e-01	3.20e-01
REACTOME FERTILIZATION	26	5.21e-02	-2.20e-01	3.20e-01
REACTOME REGULATION OF KIT SIGNALING	16	5.22e-02	-2.80e-01	3.20e-01
REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	15	5.23e-02	2.89e-01	3.20e-01
REACTOME PEPTIDE LIGAND BINDING RECEPTORS	188	5.23e-02	8.21e-02	3.20e-01
REACTOME ASPIRIN ADME	42	5.25e-02	-1.73e-01	3.20e-01
REACTOME RECYCLING OF EIF2 GDP	7	5.27e-02	-4.23e-01	3.20e-01
REACTOME AQUAPORIN MEDIATED TRANSPORT	51	5.28e-02	1.57e-01	3.20e-01
REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS	63	5.31e-02	-1.41e-01	3.21e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2	17	5.35e-02	2.70e-01	3.22e-01
REACTOME PERK REGULATES GENE EXPRESSION	31	5.38e-02	-2.00e-01	3.23e-01
REACTOME DEFECTIVE CSF2RB CAUSES SMDP5	7	5.40e-02	4.21e-01	3.23e-01
REACTOME DISEASES ASSOCIATED WITH SURFACTANT METABOLISM	9	5.44e-02	3.70e-01	3.23e-01
REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER	18	5.49e-02	-2.61e-01	3.25e-01
REACTOME HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE	43	5.53e-02	-1.69e-01	3.27e-01
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION	361	5.58e-02	-5.86e-02	3.28e-01
REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES	27	5.62e-02	-2.12e-01	3.28e-01
REACTOME SEROTONIN RECEPTORS	11	5.62e-02	3.32e-01	3.28e-01
REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	9	5.72e-02	3.66e-01	3.31e-01
REACTOME FATTY ACIDS	15	5.72e-02	-2.84e-01	3.31e-01
REACTOME MAPK FAMILY SIGNALING CASCADES	314	5.73e-02	-6.24e-02	3.31e-01
REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	99	5.82e-02	-1.10e-01	3.35e-01
REACTOME NRAGE SIGNALS DEATH THROUGH JNK	53	5.86e-02	1.50e-01	3.36e-01
REACTOME ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS	24	5.87e-02	2.23e-01	3.36e-01
REACTOME INTERLEUKIN 10 SIGNALING	43	6.01e-02	-1.66e-01	3.42e-01
REACTOME FGFRL1 MODULATION OF FGFR1 SIGNALING	13	6.06e-02	3.01e-01	3.44e-01
REACTOME VXPX CARGO TARGETING TO CILIUM	20	6.09e-02	2.42e-01	3.45e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH METHYLATION	19	6.15e-02	-2.48e-01	3.47e-01
REACTOME FORMATION OF THE CORNIFIED ENVELOPE	125	6.16e-02	9.68e-02	3.47e-01
REACTOME REGULATION OF PTEN STABILITY AND ACTIVITY	67	6.23e-02	-1.32e-01	3.49e-01
REACTOME TYROSINE CATABOLISM	5	6.29e-02	4.80e-01	3.52e-01
REACTOME MITOCHONDRIAL PROTEIN IMPORT	58	6.32e-02	-1.41e-01	3.52e-01
REACTOME TRAFFICKING OF AMPA RECEPTORS	29	6.41e-02	1.99e-01	3.54e-01
REACTOME NONCANONICAL ACTIVATION OF NOTCH3	8	6.41e-02	-3.78e-01	3.54e-01
REACTOME FC EPSILON RECEPTOR FCERI SIGNALING	127	6.44e-02	-9.50e-02	3.55e-01
REACTOME INTERFERON ALPHA BETA SIGNALING	70	6.57e-02	-1.27e-01	3.61e-01
REACTOME ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS	7	6.61e-02	4.01e-01	3.62e-01
REACTOME DISSOLUTION OF FIBRIN CLOT	13	6.63e-02	2.94e-01	3.62e-01
REACTOME CYCLIN D ASSOCIATED EVENTS IN G1	46	6.68e-02	-1.56e-01	3.62e-01
REACTOME TRNA MODIFICATION IN THE MITOCHONDRION	8	6.69e-02	-3.74e-01	3.62e-01
REACTOME GLYCOSAMINOGLYCAN METABOLISM	118	6.73e-02	9.75e-02	3.62e-01
REACTOME TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7	12	6.75e-02	-3.05e-01	3.62e-01
REACTOME DISEASES OF DNA REPAIR	51	6.75e-02	-1.48e-01	3.62e-01
REACTOME SHC1 EVENTS IN EGFR SIGNALING	14	6.81e-02	-2.82e-01	3.64e-01
REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	91	6.87e-02	-1.10e-01	3.66e-01
REACTOME HDR THROUGH HOMOLOGOUS RECOMBINATION HRR	66	6.97e-02	-1.29e-01	3.70e-01
REACTOME TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY	30	7.01e-02	-1.91e-01	3.72e-01
REACTOME CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT	19	7.05e-02	-2.40e-01	3.72e-01
REACTOME PRE NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM	6	7.11e-02	4.25e-01	3.74e-01
REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE	9	7.14e-02	-3.47e-01	3.75e-01
REACTOME HISTIDINE CATABOLISM	8	7.40e-02	3.65e-01	3.87e-01
REACTOME DNA DAMAGE REVERSAL	8	7.43e-02	3.64e-01	3.87e-01
REACTOME DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS	14	7.47e-02	2.75e-01	3.88e-01
REACTOME O LINKED GLYCOSYLATION	109	7.52e-02	9.86e-02	3.89e-01
REACTOME TOLL LIKE RECEPTOR 9 TLR9 CASCADE	100	7.54e-02	-1.03e-01	3.89e-01
REACTOME VEGFR2 MEDIATED CELL PROLIFERATION	19	7.57e-02	2.35e-01	3.90e-01
REACTOME SUMOYLATION OF DNA METHYLATION PROTEINS	16	7.72e-02	2.55e-01	3.94e-01
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES	255	7.73e-02	6.43e-02	3.94e-01
REACTOME INTERLEUKIN 2 SIGNALING	11	7.73e-02	-3.08e-01	3.94e-01
REACTOME REGULATED NECROSIS	57	7.76e-02	-1.35e-01	3.95e-01
REACTOME CDC42 GTPASE CYCLE	144	7.84e-02	8.50e-02	3.97e-01
REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER	81	7.98e-02	-1.13e-01	4.03e-01
REACTOME RHOQ GTPASE CYCLE	57	8.05e-02	1.34e-01	4.05e-01
REACTOME G ALPHA Q SIGNALLING EVENTS	206	8.12e-02	7.05e-02	4.08e-01
REACTOME TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX	10	8.15e-02	-3.18e-01	4.08e-01
REACTOME REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS	15	8.21e-02	-2.59e-01	4.10e-01
REACTOME HIV LIFE CYCLE	145	8.29e-02	-8.34e-02	4.11e-01
REACTOME NR1H2 AND NR1H3 MEDIATED SIGNALING	46	8.31e-02	1.48e-01	4.11e-01
REACTOME OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS	8	8.32e-02	3.54e-01	4.11e-01
REACTOME CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER	25	8.33e-02	2.00e-01	4.11e-01
REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	26	8.47e-02	-1.95e-01	4.16e-01
REACTOME CELLULAR RESPONSE TO HEAT STRESS	99	8.50e-02	-1.00e-01	4.17e-01
REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING	45	8.53e-02	-1.48e-01	4.17e-01
REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	79	8.57e-02	-1.12e-01	4.17e-01
REACTOME HIV TRANSCRIPTION INITIATION	43	8.69e-02	-1.51e-01	4.22e-01
REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	26	8.86e-02	-1.93e-01	4.28e-01
REACTOME INTERFERON SIGNALING	193	8.91e-02	-7.10e-02	4.28e-01
REACTOME DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA	77	8.93e-02	-1.12e-01	4.28e-01
REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	46	8.94e-02	-1.45e-01	4.28e-01
REACTOME TRANSCRIPTIONAL REGULATION BY TP53	351	8.95e-02	-5.28e-02	4.28e-01
REACTOME BICARBONATE TRANSPORTERS	10	9.04e-02	3.09e-01	4.31e-01
REACTOME SIGNALING BY ERBB4	57	9.06e-02	-1.30e-01	4.31e-01
REACTOME FGFR1C LIGAND BINDING AND ACTIVATION	11	9.13e-02	2.94e-01	4.33e-01
REACTOME INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION	21	9.26e-02	2.12e-01	4.38e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS	7	9.32e-02	3.66e-01	4.39e-01
REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	19	9.32e-02	2.22e-01	4.39e-01
REACTOME KEAP1 NFE2L2 PATHWAY	104	9.59e-02	-9.45e-02	4.49e-01
REACTOME CD22 MEDIATED BCR REGULATION	5	9.59e-02	-4.30e-01	4.49e-01
REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX	36	9.78e-02	1.59e-01	4.53e-01
REACTOME COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM	21	9.78e-02	2.09e-01	4.53e-01
REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	46	9.80e-02	-1.41e-01	4.53e-01
REACTOME HDMS DEMETHYLATE HISTONES	40	9.80e-02	-1.51e-01	4.53e-01
REACTOME THE NLRP3 INFLAMMASOME	16	9.94e-02	-2.38e-01	4.58e-01
REACTOME UNFOLDED PROTEIN RESPONSE UPR	88	1.00e-01	-1.01e-01	4.60e-01
REACTOME PHASE 3 RAPID REPOLARISATION	8	1.01e-01	3.35e-01	4.64e-01
REACTOME INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING	103	1.03e-01	-9.30e-02	4.69e-01
REACTOME SIGNALING BY FLT3 ITD AND TKD MUTANTS	16	1.03e-01	-2.36e-01	4.69e-01
REACTOME TRNA PROCESSING	105	1.03e-01	-9.21e-02	4.69e-01
REACTOME TRANSPORT OF FATTY ACIDS	8	1.03e-01	3.33e-01	4.69e-01
REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	17	1.04e-01	-2.28e-01	4.69e-01
REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS	12	1.04e-01	-2.71e-01	4.69e-01
REACTOME REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM	11	1.04e-01	2.83e-01	4.69e-01
REACTOME EARLY PHASE OF HIV LIFE CYCLE	14	1.05e-01	-2.50e-01	4.72e-01
REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	39	1.06e-01	1.50e-01	4.72e-01
REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS	188	1.06e-01	-6.83e-02	4.72e-01
REACTOME EGFR INTERACTS WITH PHOSPHOLIPASE C GAMMA	9	1.06e-01	-3.11e-01	4.72e-01
REACTOME GDP FUCOSE BIOSYNTHESIS	6	1.08e-01	3.78e-01	4.81e-01
REACTOME PEPTIDE HORMONE BIOSYNTHESIS	13	1.10e-01	2.56e-01	4.87e-01
REACTOME PHASE 2 PLATEAU PHASE	14	1.11e-01	2.46e-01	4.88e-01
REACTOME SIGNALING BY SCF KIT	42	1.11e-01	-1.42e-01	4.88e-01
REACTOME MODULATION BY MTB OF HOST IMMUNE SYSTEM	6	1.11e-01	-3.75e-01	4.89e-01
REACTOME PASSIVE TRANSPORT BY AQUAPORINS	13	1.12e-01	2.55e-01	4.90e-01
REACTOME TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT	18	1.14e-01	-2.15e-01	4.96e-01
REACTOME SLC TRANSPORTER DISORDERS	94	1.14e-01	9.43e-02	4.96e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX2	117	1.14e-01	-8.46e-02	4.96e-01
REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	20	1.15e-01	-2.04e-01	4.99e-01
REACTOME ANCHORING FIBRIL FORMATION	13	1.17e-01	2.51e-01	5.08e-01
REACTOME PKA ACTIVATION IN GLUCAGON SIGNALLING	17	1.18e-01	2.19e-01	5.09e-01
REACTOME SARS COV 2 ACTIVATES MODULATES INNATE AND ADAPTIVE IMMUNE RESPONSES	118	1.20e-01	-8.30e-02	5.13e-01
REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	53	1.20e-01	-1.24e-01	5.13e-01
REACTOME AMINE LIGAND BINDING RECEPTORS	40	1.20e-01	1.42e-01	5.13e-01
REACTOME TIE2 SIGNALING	18	1.21e-01	-2.11e-01	5.13e-01
REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3	679	1.21e-01	-3.49e-02	5.13e-01
REACTOME BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA	17	1.23e-01	-2.16e-01	5.20e-01
REACTOME PINK1 PRKN MEDIATED MITOPHAGY	22	1.24e-01	-1.90e-01	5.22e-01
REACTOME TRANSLESION SYNTHESIS BY POLK	17	1.24e-01	-2.16e-01	5.22e-01
REACTOME DEFECTIVE F9 ACTIVATION	5	1.24e-01	3.97e-01	5.22e-01
REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	78	1.24e-01	-1.01e-01	5.23e-01
REACTOME TRANSPORT OF ORGANIC ANIONS	10	1.25e-01	2.80e-01	5.25e-01
REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	16	1.27e-01	-2.20e-01	5.31e-01
REACTOME CREB3 FACTORS ACTIVATE GENES	8	1.28e-01	-3.11e-01	5.34e-01
REACTOME REGULATION OF INSULIN SECRETION	77	1.29e-01	1.00e-01	5.37e-01
REACTOME GENERATION OF SECOND MESSENGER MOLECULES	30	1.30e-01	-1.60e-01	5.38e-01
REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	296	1.30e-01	-5.12e-02	5.38e-01
REACTOME TNFR1 INDUCED PROAPOPTOTIC SIGNALING	23	1.31e-01	-1.82e-01	5.38e-01
REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	19	1.31e-01	-2.00e-01	5.38e-01
REACTOME NICOTINATE METABOLISM	31	1.32e-01	1.56e-01	5.39e-01
REACTOME INTERLEUKIN 23 SIGNALING	9	1.32e-01	2.90e-01	5.39e-01
REACTOME DEFECTIVE LFNG CAUSES SCDO3	5	1.32e-01	3.89e-01	5.39e-01
REACTOME SENSORY PERCEPTION OF TASTE	47	1.32e-01	1.27e-01	5.39e-01
REACTOME ACYL CHAIN REMODELING OF DAG AND TAG	5	1.34e-01	3.87e-01	5.44e-01
REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX	13	1.34e-01	-2.40e-01	5.44e-01
REACTOME EGFR DOWNREGULATION	30	1.35e-01	-1.58e-01	5.44e-01
REACTOME RNA POLYMERASE III CHAIN ELONGATION	18	1.36e-01	-2.03e-01	5.45e-01
REACTOME COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING	38	1.36e-01	-1.40e-01	5.45e-01
REACTOME BINDING OF TCF LEF CTNNB1 TO TARGET GENE PROMOTERS	8	1.36e-01	-3.05e-01	5.45e-01
REACTOME MITOPHAGY	28	1.37e-01	-1.62e-01	5.48e-01
REACTOME SIGNALING BY ALK IN CANCER	53	1.38e-01	-1.18e-01	5.51e-01
REACTOME TRANSPORT OF SMALL MOLECULES	697	1.39e-01	3.29e-02	5.51e-01
REACTOME REACTIONS SPECIFIC TO THE COMPLEX N GLYCAN SYNTHESIS PATHWAY	10	1.39e-01	2.70e-01	5.51e-01
REACTOME IRAK1 RECRUITS IKK COMPLEX	12	1.39e-01	-2.46e-01	5.51e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR4	14	1.40e-01	2.28e-01	5.51e-01
REACTOME PTK6 REGULATES CELL CYCLE	6	1.40e-01	-3.48e-01	5.51e-01
REACTOME LDL REMODELING	6	1.40e-01	-3.48e-01	5.51e-01
REACTOME INTERLEUKIN 37 SIGNALING	20	1.41e-01	1.90e-01	5.54e-01
REACTOME REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS	7	1.42e-01	3.21e-01	5.54e-01
REACTOME KETONE BODY METABOLISM	9	1.42e-01	2.82e-01	5.54e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX	91	1.42e-01	-8.90e-02	5.54e-01
REACTOME N GLYCAN ANTENNAE ELONGATION	15	1.42e-01	2.19e-01	5.54e-01
REACTOME RHOU GTPASE CYCLE	37	1.44e-01	1.39e-01	5.56e-01
REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	7	1.44e-01	3.19e-01	5.56e-01
REACTOME DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B	7	1.45e-01	3.18e-01	5.58e-01
REACTOME FGFR2 LIGAND BINDING AND ACTIVATION	19	1.45e-01	1.93e-01	5.59e-01
REACTOME MYD88 INDEPENDENT TLR4 CASCADE	103	1.46e-01	-8.29e-02	5.61e-01
REACTOME CARGO CONCENTRATION IN THE ER	32	1.47e-01	-1.48e-01	5.61e-01
REACTOME PRE NOTCH PROCESSING IN GOLGI	18	1.47e-01	1.97e-01	5.61e-01
REACTOME NICOTINAMIDE SALVAGING	19	1.47e-01	1.92e-01	5.61e-01
REACTOME REGULATION OF NPAS4 GENE TRANSCRIPTION	5	1.47e-01	-3.74e-01	5.61e-01
REACTOME PREDNISONE ADME	10	1.49e-01	-2.64e-01	5.63e-01
REACTOME KERATAN SULFATE BIOSYNTHESIS	28	1.49e-01	1.58e-01	5.63e-01
REACTOME INTEGRATION OF PROVIRUS	9	1.49e-01	-2.78e-01	5.63e-01
REACTOME ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS	87	1.50e-01	8.94e-02	5.63e-01
REACTOME REGULATION OF BETA CELL DEVELOPMENT	41	1.50e-01	-1.30e-01	5.63e-01
REACTOME SIGNALING BY FGFR1 IN DISEASE	38	1.50e-01	1.35e-01	5.64e-01
REACTOME CARDIAC CONDUCTION	125	1.51e-01	7.44e-02	5.64e-01
REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY	26	1.51e-01	1.63e-01	5.64e-01
REACTOME VISUAL PHOTOTRANSDUCTION	93	1.51e-01	8.61e-02	5.64e-01
REACTOME ACYL CHAIN REMODELLING OF PI	17	1.52e-01	-2.01e-01	5.64e-01
REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	17	1.53e-01	-2.00e-01	5.67e-01
REACTOME FRS MEDIATED FGFR1 SIGNALING	23	1.54e-01	1.72e-01	5.71e-01
REACTOME SENSORY PERCEPTION	555	1.54e-01	-3.54e-02	5.71e-01
REACTOME SIGNALING BY EGFR	49	1.55e-01	-1.17e-01	5.72e-01
REACTOME TRNA PROCESSING IN THE NUCLEUS	58	1.55e-01	-1.08e-01	5.72e-01
REACTOME SIGNALING BY ALK	26	1.57e-01	-1.60e-01	5.76e-01
REACTOME TOXICITY OF BOTULINUM TOXIN TYPE D BOTD	5	1.58e-01	-3.65e-01	5.78e-01
REACTOME TRANSPORT AND SYNTHESIS OF PAPS	6	1.59e-01	3.32e-01	5.81e-01
REACTOME FATTY ACIDS BOUND TO GPR40 FFAR1 REGULATE INSULIN SECRETION	8	1.59e-01	2.87e-01	5.82e-01
REACTOME MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION	15	1.60e-01	-2.09e-01	5.82e-01
REACTOME PROTEIN FOLDING	96	1.60e-01	-8.29e-02	5.82e-01
REACTOME METABOLISM OF COFACTORS	19	1.61e-01	-1.86e-01	5.83e-01
REACTOME SIGNALING BY FGFR IN DISEASE	62	1.62e-01	1.03e-01	5.85e-01
REACTOME REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE	81	1.63e-01	-8.96e-02	5.88e-01
REACTOME FGFR3B LIGAND BINDING AND ACTIVATION	7	1.63e-01	3.04e-01	5.88e-01
REACTOME PHENYLALANINE AND TYROSINE METABOLISM	11	1.64e-01	2.42e-01	5.89e-01
REACTOME INTESTINAL ABSORPTION	5	1.65e-01	3.59e-01	5.89e-01
REACTOME SIGNALING BY NOTCH1 T 7 9 NOTCH1 M1580 K2555 TRANSLOCATION MUTANT	7	1.66e-01	3.03e-01	5.89e-01
REACTOME PI 3K CASCADE FGFR1	21	1.66e-01	1.74e-01	5.89e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	24	1.66e-01	1.63e-01	5.89e-01
REACTOME REGULATION OF TP53 ACTIVITY	156	1.66e-01	-6.42e-02	5.89e-01
REACTOME SIGNALING BY CSF3 G CSF	30	1.67e-01	-1.46e-01	5.89e-01
REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	37	1.67e-01	-1.31e-01	5.89e-01
REACTOME REGULATION OF RAS BY GAPS	66	1.67e-01	-9.83e-02	5.89e-01
REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA	11	1.68e-01	-2.40e-01	5.89e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION	41	1.68e-01	-1.25e-01	5.89e-01
REACTOME MITOTIC G2 G2 M PHASES	194	1.70e-01	-5.72e-02	5.94e-01
REACTOME RECYCLING PATHWAY OF L1	43	1.70e-01	1.21e-01	5.94e-01
REACTOME PD 1 SIGNALING	21	1.70e-01	-1.73e-01	5.95e-01
REACTOME VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS	42	1.71e-01	1.22e-01	5.95e-01
REACTOME FRS MEDIATED FGFR2 SIGNALING	24	1.72e-01	1.61e-01	5.95e-01
REACTOME SCAVENGING BY CLASS F RECEPTORS	6	1.73e-01	-3.21e-01	5.95e-01
REACTOME METHYLATION	14	1.73e-01	-2.10e-01	5.95e-01
REACTOME ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING	9	1.73e-01	-2.62e-01	5.95e-01
REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING	6	1.73e-01	-3.21e-01	5.95e-01
REACTOME PHASE 4 RESTING MEMBRANE POTENTIAL	19	1.73e-01	1.80e-01	5.95e-01
REACTOME FRS MEDIATED FGFR3 SIGNALING	19	1.73e-01	1.80e-01	5.95e-01
REACTOME CONSTITUTIVE SIGNALING BY EGFRVIII	15	1.74e-01	-2.03e-01	5.96e-01
REACTOME ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS	27	1.74e-01	-1.51e-01	5.96e-01
REACTOME RETINOID CYCLE DISEASE EVENTS	11	1.76e-01	2.36e-01	5.99e-01
REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	12	1.76e-01	2.25e-01	6.00e-01
REACTOME FOLDING OF ACTIN BY CCT TRIC	10	1.76e-01	-2.47e-01	6.00e-01
REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	37	1.78e-01	1.28e-01	6.02e-01
REACTOME MULTIFUNCTIONAL ANION EXCHANGERS	9	1.78e-01	2.59e-01	6.02e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS	9	1.80e-01	2.58e-01	6.08e-01
REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	38	1.81e-01	-1.26e-01	6.08e-01
REACTOME CALCITONIN LIKE LIGAND RECEPTORS	10	1.81e-01	-2.44e-01	6.08e-01
REACTOME SHC MEDIATED CASCADE FGFR1	21	1.81e-01	1.69e-01	6.08e-01
REACTOME GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION	30	1.84e-01	1.40e-01	6.17e-01
REACTOME PI 3K CASCADE FGFR2	22	1.86e-01	1.63e-01	6.23e-01
REACTOME PI 3K CASCADE FGFR3	17	1.87e-01	1.85e-01	6.23e-01
REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	36	1.87e-01	-1.27e-01	6.23e-01
REACTOME G ALPHA 12 13 SIGNALLING EVENTS	74	1.88e-01	8.86e-02	6.23e-01
REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	13	1.88e-01	2.11e-01	6.25e-01
REACTOME REGULATED PROTEOLYSIS OF P75NTR	11	1.89e-01	-2.29e-01	6.26e-01
REACTOME O LINKED GLYCOSYLATION OF MUCINS	61	1.90e-01	9.71e-02	6.26e-01
REACTOME SYNTHESIS OF PIPS AT THE ER MEMBRANE	5	1.90e-01	3.38e-01	6.27e-01
REACTOME MTORC1 MEDIATED SIGNALLING	23	1.91e-01	-1.58e-01	6.28e-01
REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	12	1.92e-01	-2.17e-01	6.31e-01
REACTOME ALK MUTANTS BIND TKIS	12	1.93e-01	-2.17e-01	6.31e-01
REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES	39	1.93e-01	-1.20e-01	6.31e-01
REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH	62	1.94e-01	9.55e-02	6.32e-01
REACTOME CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS	100	1.94e-01	-7.51e-02	6.33e-01
REACTOME EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION	27	1.95e-01	1.44e-01	6.33e-01
REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION	23	1.95e-01	-1.56e-01	6.33e-01
REACTOME C TYPE LECTIN RECEPTORS CLRS	136	1.95e-01	-6.43e-02	6.33e-01
REACTOME ARACHIDONIC ACID METABOLISM	57	1.96e-01	-9.90e-02	6.34e-01
REACTOME CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND	16	1.97e-01	-1.86e-01	6.36e-01
REACTOME INTERLEUKIN 20 FAMILY SIGNALING	25	1.98e-01	1.49e-01	6.37e-01
REACTOME COENZYME A BIOSYNTHESIS	8	1.98e-01	-2.63e-01	6.37e-01
REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS	66	1.99e-01	9.15e-02	6.37e-01
REACTOME METABOLISM OF POLYAMINES	56	1.99e-01	-9.92e-02	6.37e-01
REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS	418	2.02e-01	-3.64e-02	6.38e-01
REACTOME REGULATION OF GENE EXPRESSION IN ENDOCRINE COMMITTED NEUROG3 PROGENITOR CELLS	5	2.02e-01	-3.30e-01	6.38e-01
REACTOME CHAPERONE MEDIATED AUTOPHAGY	20	2.02e-01	-1.65e-01	6.38e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER	28	2.02e-01	-1.39e-01	6.38e-01
REACTOME METALLOTHIONEINS BIND METALS	11	2.02e-01	2.22e-01	6.38e-01
REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS	28	2.03e-01	-1.39e-01	6.38e-01
REACTOME MITOTIC PROMETAPHASE	194	2.03e-01	-5.29e-02	6.38e-01
REACTOME RSK ACTIVATION	5	2.04e-01	3.28e-01	6.38e-01
REACTOME DUAL INCISION IN GG NER	39	2.04e-01	-1.18e-01	6.38e-01
REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	18	2.04e-01	1.73e-01	6.38e-01
REACTOME MATURATION OF PROTEIN 3A	9	2.04e-01	2.44e-01	6.38e-01
REACTOME SHC MEDIATED CASCADE FGFR3	17	2.05e-01	1.78e-01	6.38e-01
REACTOME ACTIVATION OF MATRIX METALLOPROTEINASES	30	2.05e-01	1.34e-01	6.38e-01
REACTOME INWARDLY RECTIFYING K CHANNELS	35	2.05e-01	1.24e-01	6.38e-01
REACTOME HEME SIGNALING	47	2.05e-01	1.07e-01	6.38e-01
REACTOME DRUG MEDIATED INHIBITION OF CDK4 CDK6 ACTIVITY	5	2.06e-01	-3.27e-01	6.38e-01
REACTOME GASTRULATION	49	2.07e-01	-1.04e-01	6.40e-01
REACTOME G0 AND EARLY G1	27	2.08e-01	-1.40e-01	6.41e-01
REACTOME INITIATION OF NUCLEAR ENVELOPE NE REFORMATION	18	2.08e-01	-1.71e-01	6.41e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX	19	2.08e-01	-1.67e-01	6.41e-01
REACTOME GLUCOCORTICOID BIOSYNTHESIS	10	2.08e-01	-2.30e-01	6.41e-01
REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	24	2.09e-01	-1.48e-01	6.41e-01
REACTOME REGULATION OF PTEN LOCALIZATION	8	2.10e-01	-2.56e-01	6.41e-01
REACTOME SYNTHESIS OF KETONE BODIES	8	2.10e-01	2.56e-01	6.41e-01
REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP	41	2.10e-01	1.13e-01	6.41e-01
REACTOME SIGNALING BY VEGF	102	2.11e-01	7.18e-02	6.41e-01
REACTOME JOSEPHIN DOMAIN DUBS	11	2.11e-01	-2.18e-01	6.41e-01
REACTOME CLEC7A DECTIN 1 SIGNALING	97	2.12e-01	-7.33e-02	6.44e-01
REACTOME INFLAMMASOMES	21	2.13e-01	-1.57e-01	6.44e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS	12	2.13e-01	2.08e-01	6.44e-01
REACTOME PCP CE PATHWAY	91	2.14e-01	-7.54e-02	6.45e-01
REACTOME MIRO GTPASE CYCLE	8	2.14e-01	-2.53e-01	6.46e-01
REACTOME HSF1 ACTIVATION	29	2.16e-01	-1.33e-01	6.50e-01
REACTOME REGULATION OF NF KAPPA B SIGNALING	17	2.17e-01	-1.73e-01	6.53e-01
REACTOME LAMININ INTERACTIONS	28	2.19e-01	1.34e-01	6.54e-01
REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS	14	2.19e-01	-1.90e-01	6.54e-01
REACTOME SURFACTANT METABOLISM	28	2.19e-01	1.34e-01	6.54e-01
REACTOME RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX	29	2.20e-01	-1.31e-01	6.56e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN	21	2.21e-01	-1.54e-01	6.56e-01
REACTOME NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS	11	2.21e-01	-2.13e-01	6.57e-01
REACTOME METABOLISM OF PORPHYRINS	26	2.22e-01	-1.38e-01	6.58e-01
REACTOME PENTOSE PHOSPHATE PATHWAY	12	2.23e-01	2.03e-01	6.59e-01
REACTOME FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS	8	2.25e-01	2.48e-01	6.62e-01
REACTOME HDL ASSEMBLY	8	2.25e-01	2.48e-01	6.62e-01
REACTOME VITAMIN C ASCORBATE METABOLISM	8	2.26e-01	-2.47e-01	6.62e-01
REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	15	2.27e-01	1.80e-01	6.62e-01
REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	11	2.27e-01	2.10e-01	6.62e-01
REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA	28	2.28e-01	-1.32e-01	6.62e-01
REACTOME FCGR3A MEDIATED IL10 SYNTHESIS	36	2.28e-01	1.16e-01	6.62e-01
REACTOME ATTENUATION PHASE	27	2.28e-01	-1.34e-01	6.62e-01
REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION	31	2.28e-01	1.25e-01	6.62e-01
REACTOME SIGNALING BY NTRKS	132	2.28e-01	-6.07e-02	6.62e-01
REACTOME G ALPHA S SIGNALLING EVENTS	155	2.29e-01	5.60e-02	6.62e-01
REACTOME KSRP KHSRP BINDS AND DESTABILIZES MRNA	17	2.29e-01	-1.69e-01	6.62e-01
REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS	6	2.29e-01	2.84e-01	6.62e-01
REACTOME PYRUVATE METABOLISM	29	2.30e-01	1.29e-01	6.64e-01
REACTOME HEME BIOSYNTHESIS	13	2.32e-01	-1.92e-01	6.64e-01
REACTOME SIGNALING BY TGFB FAMILY MEMBERS	119	2.32e-01	-6.35e-02	6.64e-01
REACTOME FORMATION OF PARAXIAL MESODERM	22	2.32e-01	-1.47e-01	6.64e-01
REACTOME RHOC GTPASE CYCLE	71	2.32e-01	8.21e-02	6.64e-01
REACTOME FRUCTOSE METABOLISM	7	2.33e-01	2.60e-01	6.64e-01
REACTOME DRUG ADME	103	2.33e-01	-6.80e-02	6.64e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	27	2.33e-01	-1.33e-01	6.64e-01
REACTOME PLATELET CALCIUM HOMEOSTASIS	27	2.33e-01	1.32e-01	6.64e-01
REACTOME COLLAGEN CHAIN TRIMERIZATION	42	2.36e-01	1.06e-01	6.69e-01
REACTOME TRANSLESION SYNTHESIS BY POLH	19	2.37e-01	-1.57e-01	6.71e-01
REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS	42	2.37e-01	-1.05e-01	6.71e-01
REACTOME GRB7 EVENTS IN ERBB2 SIGNALING	5	2.38e-01	3.04e-01	6.74e-01
REACTOME PKMTS METHYLATE HISTONE LYSINES	64	2.40e-01	-8.50e-02	6.76e-01
REACTOME RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK	47	2.40e-01	-9.91e-02	6.76e-01
REACTOME FCERI MEDIATED CA 2 MOBILIZATION	30	2.40e-01	-1.24e-01	6.76e-01
REACTOME FORMATION OF INCISION COMPLEX IN GG NER	40	2.41e-01	-1.07e-01	6.77e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION	29	2.42e-01	1.25e-01	6.79e-01
REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	89	2.43e-01	7.16e-02	6.80e-01
REACTOME MAP2K AND MAPK ACTIVATION	38	2.44e-01	-1.09e-01	6.82e-01
REACTOME SUPPRESSION OF PHAGOSOMAL MATURATION	13	2.46e-01	-1.86e-01	6.84e-01
REACTOME DISEASES OF BASE EXCISION REPAIR	5	2.46e-01	3.00e-01	6.84e-01
REACTOME PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR	21	2.47e-01	-1.46e-01	6.85e-01
REACTOME REGULATION BY C FLIP	11	2.50e-01	-2.00e-01	6.91e-01
REACTOME DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A	5	2.50e-01	2.97e-01	6.91e-01
REACTOME RECYCLING OF BILE ACIDS AND SALTS	18	2.50e-01	1.57e-01	6.91e-01
REACTOME REGULATION OF IFNG SIGNALING	14	2.51e-01	-1.77e-01	6.91e-01
REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION	23	2.51e-01	1.38e-01	6.91e-01
REACTOME ASSEMBLY OF THE HIV VIRION	16	2.52e-01	-1.65e-01	6.91e-01
REACTOME CRISTAE FORMATION	27	2.52e-01	-1.27e-01	6.91e-01
REACTOME RESOLUTION OF SISTER CHROMATID COHESION	120	2.53e-01	-6.05e-02	6.91e-01
REACTOME KERATAN SULFATE KERATIN METABOLISM	34	2.53e-01	1.13e-01	6.91e-01
REACTOME DISEASES OF GLYCOSYLATION	137	2.53e-01	5.66e-02	6.91e-01
REACTOME MITOTIC SPINDLE CHECKPOINT	109	2.54e-01	-6.32e-02	6.94e-01
REACTOME OPIOID SIGNALLING	89	2.56e-01	6.97e-02	6.95e-01
REACTOME MET ACTIVATES PTPN11	5	2.56e-01	-2.94e-01	6.95e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS	14	2.56e-01	1.75e-01	6.96e-01
REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	22	2.58e-01	-1.39e-01	6.97e-01
REACTOME GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION	42	2.59e-01	1.01e-01	6.97e-01
REACTOME FCERI MEDIATED NF KB ACTIVATION	78	2.59e-01	-7.39e-02	6.97e-01
REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	23	2.60e-01	1.36e-01	6.97e-01
REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS	33	2.61e-01	-1.13e-01	6.97e-01
REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION	12	2.61e-01	1.88e-01	6.97e-01
REACTOME RHOA GTPASE CYCLE	142	2.61e-01	5.46e-02	6.97e-01
REACTOME RHO GTPASES ACTIVATE WASPS AND WAVES	34	2.61e-01	-1.11e-01	6.97e-01
REACTOME SUMOYLATION OF INTRACELLULAR RECEPTORS	29	2.61e-01	1.21e-01	6.97e-01
REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	49	2.61e-01	-9.27e-02	6.97e-01
REACTOME GABA B RECEPTOR ACTIVATION	43	2.61e-01	9.90e-02	6.97e-01
REACTOME RA BIOSYNTHESIS PATHWAY	22	2.62e-01	-1.38e-01	6.97e-01
REACTOME HYALURONAN BIOSYNTHESIS AND EXPORT	5	2.63e-01	2.89e-01	6.99e-01
REACTOME VITAMIN B1 THIAMIN METABOLISM	5	2.64e-01	-2.89e-01	6.99e-01
REACTOME NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS	25	2.64e-01	-1.29e-01	6.99e-01
REACTOME REDUCTION OF CYTOSOLIC CA LEVELS	11	2.64e-01	1.94e-01	6.99e-01
REACTOME METABOLISM OF LIPIDS	709	2.65e-01	2.46e-02	6.99e-01
REACTOME REGULATION OF MECP2 EXPRESSION AND ACTIVITY	30	2.65e-01	1.18e-01	6.99e-01
REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	14	2.67e-01	1.71e-01	7.03e-01
REACTOME OVARIAN TUMOR DOMAIN PROTEASES	36	2.68e-01	-1.07e-01	7.05e-01
REACTOME PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING	11	2.69e-01	1.93e-01	7.05e-01
REACTOME GPVI MEDIATED ACTIVATION CASCADE	35	2.70e-01	-1.08e-01	7.07e-01
REACTOME MYOCLONIC EPILEPSY OF LAFORA	9	2.70e-01	-2.12e-01	7.07e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES	61	2.72e-01	-8.12e-02	7.11e-01
REACTOME UBIQUINOL BIOSYNTHESIS	8	2.73e-01	-2.24e-01	7.11e-01
REACTOME CD28 DEPENDENT VAV1 PATHWAY	11	2.73e-01	-1.91e-01	7.11e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES	12	2.74e-01	1.83e-01	7.11e-01
REACTOME MRNA EDITING C TO U CONVERSION	8	2.75e-01	-2.23e-01	7.12e-01
REACTOME ESTABLISHMENT OF SISTER CHROMATID COHESION	9	2.75e-01	-2.10e-01	7.12e-01
REACTOME ANDROGEN BIOSYNTHESIS	11	2.76e-01	1.90e-01	7.12e-01
REACTOME SIGNALING BY INSULIN RECEPTOR	80	2.77e-01	7.03e-02	7.12e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION TERMINATION	23	2.78e-01	-1.31e-01	7.12e-01
REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION	74	2.78e-01	7.29e-02	7.12e-01
REACTOME SYNTHESIS OF PG	8	2.78e-01	2.21e-01	7.12e-01
REACTOME BUDDING AND MATURATION OF HIV VIRION	28	2.79e-01	-1.18e-01	7.12e-01
REACTOME P75NTR REGULATES AXONOGENESIS	9	2.79e-01	2.08e-01	7.12e-01
REACTOME RESPONSE TO METAL IONS	14	2.79e-01	1.67e-01	7.12e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS	7	2.79e-01	-2.36e-01	7.12e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR2	29	2.79e-01	1.16e-01	7.12e-01
REACTOME INTERLEUKIN 18 SIGNALING	8	2.80e-01	2.20e-01	7.13e-01
REACTOME SIGNALING BY CSF1 M CSF IN MYELOID CELLS	30	2.81e-01	-1.14e-01	7.13e-01
REACTOME FORMATION OF APOPTOSOME	10	2.81e-01	-1.97e-01	7.13e-01
REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS	21	2.82e-01	1.36e-01	7.14e-01
REACTOME RND3 GTPASE CYCLE	41	2.83e-01	9.70e-02	7.14e-01
REACTOME PEROXISOMAL PROTEIN IMPORT	62	2.83e-01	-7.89e-02	7.14e-01
REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	15	2.84e-01	-1.60e-01	7.17e-01
REACTOME TOLL LIKE RECEPTOR CASCADES	158	2.85e-01	-4.92e-02	7.19e-01
REACTOME TNF SIGNALING	54	2.88e-01	-8.35e-02	7.24e-01
REACTOME DNA REPLICATION INITIATION	7	2.88e-01	-2.32e-01	7.24e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE	11	2.89e-01	1.85e-01	7.24e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA	27	2.90e-01	-1.18e-01	7.24e-01
REACTOME P75NTR SIGNALS VIA NF KB	15	2.90e-01	-1.58e-01	7.24e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2	13	2.91e-01	1.69e-01	7.24e-01
REACTOME APEX1 INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	7	2.92e-01	2.30e-01	7.24e-01
REACTOME DEADENYLATION DEPENDENT MRNA DECAY	56	2.92e-01	-8.14e-02	7.24e-01
REACTOME ACETYLCHOLINE REGULATES INSULIN SECRETION	10	2.93e-01	1.92e-01	7.24e-01
REACTOME BETA CATENIN INDEPENDENT WNT SIGNALING	145	2.93e-01	-5.06e-02	7.24e-01
REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	35	2.93e-01	-1.03e-01	7.24e-01
REACTOME SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA PHE	6	2.93e-01	-2.48e-01	7.24e-01
REACTOME TRIGLYCERIDE BIOSYNTHESIS	12	2.93e-01	1.75e-01	7.24e-01
REACTOME RHOB GTPASE CYCLE	67	2.94e-01	7.42e-02	7.24e-01
REACTOME IRS ACTIVATION	5	2.94e-01	2.71e-01	7.24e-01
REACTOME CLEC7A INFLAMMASOME PATHWAY	6	2.97e-01	-2.46e-01	7.28e-01
REACTOME DOWNREGULATION OF ERBB4 SIGNALING	9	2.97e-01	-2.01e-01	7.28e-01
REACTOME RRNA MODIFICATION IN THE MITOCHONDRION	6	2.97e-01	2.46e-01	7.28e-01
REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	10	2.98e-01	1.90e-01	7.28e-01
REACTOME DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS	25	2.98e-01	-1.20e-01	7.28e-01
REACTOME ARACHIDONATE PRODUCTION FROM DAG	5	2.99e-01	2.68e-01	7.28e-01
REACTOME GAP JUNCTION TRAFFICKING AND REGULATION	49	2.99e-01	8.57e-02	7.28e-01
REACTOME PROSTANOID LIGAND RECEPTORS	9	2.99e-01	-2.00e-01	7.28e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR3	24	3.01e-01	1.22e-01	7.29e-01
REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	76	3.01e-01	6.86e-02	7.29e-01
REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	16	3.01e-01	-1.49e-01	7.29e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1	31	3.02e-01	1.07e-01	7.29e-01
REACTOME INTERLEUKIN 21 SIGNALING	9	3.02e-01	-1.99e-01	7.29e-01
REACTOME CARNITINE METABOLISM	13	3.03e-01	1.65e-01	7.29e-01
REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	14	3.03e-01	1.59e-01	7.29e-01
REACTOME INTERLEUKIN 15 SIGNALING	13	3.03e-01	-1.65e-01	7.29e-01
REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	23	3.05e-01	1.24e-01	7.31e-01
REACTOME CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY	25	3.05e-01	-1.19e-01	7.31e-01
REACTOME INACTIVATION OF CSF3 G CSF SIGNALING	25	3.05e-01	-1.18e-01	7.31e-01
REACTOME RHO GTPASES ACTIVATE FORMINS	136	3.06e-01	-5.08e-02	7.31e-01
REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE	277	3.06e-01	-3.57e-02	7.31e-01
REACTOME SENSORY PERCEPTION OF SALTY TASTE	6	3.08e-01	2.40e-01	7.32e-01
REACTOME SODIUM COUPLED PHOSPHATE COTRANSPORTERS	5	3.08e-01	2.63e-01	7.32e-01
REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	93	3.08e-01	-6.11e-02	7.32e-01
REACTOME NEF MEDIATED CD8 DOWN REGULATION	7	3.11e-01	2.21e-01	7.38e-01
REACTOME OTHER INTERLEUKIN SIGNALING	24	3.11e-01	1.19e-01	7.38e-01
REACTOME HSF1 DEPENDENT TRANSACTIVATION	37	3.12e-01	-9.60e-02	7.38e-01
REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	20	3.13e-01	-1.30e-01	7.38e-01
REACTOME POLYMERASE SWITCHING	13	3.13e-01	-1.62e-01	7.38e-01
REACTOME COMMON PATHWAY OF FIBRIN CLOT FORMATION	21	3.13e-01	1.27e-01	7.38e-01
REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	31	3.15e-01	-1.04e-01	7.38e-01
REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION	26	3.16e-01	1.14e-01	7.38e-01
REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	13	3.16e-01	1.61e-01	7.38e-01
REACTOME REPRESSION OF WNT TARGET GENES	14	3.17e-01	-1.55e-01	7.38e-01
REACTOME TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE	10	3.17e-01	1.83e-01	7.38e-01
REACTOME TBC RABGAPS	40	3.17e-01	9.14e-02	7.38e-01
REACTOME TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION	5	3.17e-01	-2.58e-01	7.38e-01
REACTOME CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN	45	3.18e-01	-8.61e-02	7.38e-01
REACTOME SPRY REGULATION OF FGF SIGNALING	16	3.18e-01	-1.44e-01	7.38e-01
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	81	3.18e-01	-6.41e-02	7.38e-01
REACTOME RUNX3 REGULATES P14 ARF	10	3.18e-01	-1.82e-01	7.38e-01
REACTOME ATTACHMENT OF GPI ANCHOR TO UPAR	7	3.19e-01	-2.18e-01	7.38e-01
REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	62	3.19e-01	7.32e-02	7.38e-01
REACTOME TRIGLYCERIDE METABOLISM	35	3.22e-01	9.68e-02	7.42e-01
REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	67	3.22e-01	-7.00e-02	7.42e-01
REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION	19	3.22e-01	1.31e-01	7.42e-01
REACTOME NUCLEAR IMPORT OF REV PROTEIN	34	3.22e-01	-9.80e-02	7.42e-01
REACTOME PECAM1 INTERACTIONS	12	3.24e-01	-1.65e-01	7.42e-01
REACTOME INSULIN RECEPTOR SIGNALLING CASCADE	53	3.24e-01	7.83e-02	7.42e-01
REACTOME RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION	8	3.24e-01	2.01e-01	7.42e-01
REACTOME INTERLEUKIN 17 SIGNALING	66	3.24e-01	-7.01e-02	7.42e-01
REACTOME TRANSCRIPTION OF THE HIV GENOME	66	3.25e-01	-7.01e-02	7.42e-01
REACTOME EPHA MEDIATED GROWTH CONE COLLAPSE	29	3.26e-01	1.05e-01	7.42e-01
REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	22	3.26e-01	1.21e-01	7.42e-01
REACTOME CD209 DC SIGN SIGNALING	20	3.27e-01	-1.27e-01	7.43e-01
REACTOME SIGNALING BY BMP	27	3.27e-01	1.09e-01	7.43e-01
REACTOME IRS MEDIATED SIGNALLING	47	3.29e-01	8.23e-02	7.46e-01
REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	51	3.30e-01	-7.89e-02	7.47e-01
REACTOME FGFR1B LIGAND BINDING AND ACTIVATION	6	3.30e-01	2.30e-01	7.47e-01
REACTOME SIGNALING BY NOTCH2	32	3.31e-01	-9.92e-02	7.48e-01
REACTOME HEDGEHOG OFF STATE	111	3.32e-01	-5.34e-02	7.48e-01
REACTOME NETRIN 1 SIGNALING	49	3.32e-01	-8.01e-02	7.48e-01
REACTOME MISCELLANEOUS SUBSTRATES	12	3.33e-01	-1.61e-01	7.48e-01
REACTOME SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA	52	3.33e-01	-7.75e-02	7.48e-01
REACTOME PTEN REGULATION	135	3.34e-01	-4.82e-02	7.48e-01
REACTOME LINOLEIC ACID LA METABOLISM	7	3.34e-01	2.11e-01	7.48e-01
REACTOME AZATHIOPRINE ADME	22	3.35e-01	-1.19e-01	7.49e-01
REACTOME CHL1 INTERACTIONS	9	3.36e-01	-1.85e-01	7.49e-01
REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	16	3.36e-01	-1.39e-01	7.49e-01
REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ	6	3.36e-01	2.27e-01	7.49e-01
REACTOME PYRIMIDINE SALVAGE	10	3.37e-01	-1.75e-01	7.49e-01
REACTOME RELAXIN RECEPTORS	8	3.37e-01	1.96e-01	7.49e-01
REACTOME PTK6 PROMOTES HIF1A STABILIZATION	6	3.39e-01	-2.25e-01	7.52e-01
REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND	21	3.40e-01	1.20e-01	7.53e-01
REACTOME MET INTERACTS WITH TNS PROTEINS	5	3.41e-01	2.46e-01	7.55e-01
REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING	25	3.42e-01	-1.10e-01	7.55e-01
REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX	15	3.43e-01	-1.41e-01	7.55e-01
REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	21	3.43e-01	-1.20e-01	7.55e-01
REACTOME TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY	16	3.43e-01	-1.37e-01	7.55e-01
REACTOME CONJUGATION OF BENZOATE WITH GLYCINE	6	3.43e-01	2.23e-01	7.55e-01
REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION	42	3.44e-01	8.44e-02	7.55e-01
REACTOME SMAC XIAP REGULATED APOPTOTIC RESPONSE	7	3.47e-01	-2.05e-01	7.60e-01
REACTOME LATE ENDOSOMAL MICROAUTOPHAGY	33	3.48e-01	-9.44e-02	7.62e-01
REACTOME TLR3 MEDIATED TICAM1 DEPENDENT PROGRAMMED CELL DEATH	6	3.50e-01	-2.20e-01	7.65e-01
REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE	109	3.51e-01	-5.17e-02	7.65e-01
REACTOME TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX	14	3.51e-01	-1.44e-01	7.65e-01
REACTOME SIGNALING BY FGFR2 IN DISEASE	42	3.51e-01	8.31e-02	7.65e-01
REACTOME OAS ANTIVIRAL RESPONSE	8	3.52e-01	-1.90e-01	7.65e-01
REACTOME SIGNALLING TO P38 VIA RIT AND RIN	5	3.53e-01	-2.40e-01	7.66e-01
REACTOME FRS MEDIATED FGFR4 SIGNALING	21	3.53e-01	1.17e-01	7.66e-01
REACTOME RHO GTPASE CYCLE	423	3.54e-01	2.63e-02	7.66e-01
REACTOME UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN	6	3.55e-01	-2.18e-01	7.66e-01
REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV 1 INFECTION	5	3.55e-01	-2.39e-01	7.66e-01
REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER	77	3.58e-01	-6.06e-02	7.68e-01
REACTOME ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY	10	3.58e-01	-1.68e-01	7.68e-01
REACTOME ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE	9	3.58e-01	-1.77e-01	7.68e-01
REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	15	3.58e-01	-1.37e-01	7.68e-01
REACTOME GLUCAGON TYPE LIGAND RECEPTORS	32	3.58e-01	-9.38e-02	7.68e-01
REACTOME SYNTHESIS OF PC	27	3.59e-01	-1.02e-01	7.68e-01
REACTOME GABA RECEPTOR ACTIVATION	57	3.59e-01	7.02e-02	7.68e-01
REACTOME LGI ADAM INTERACTIONS	14	3.61e-01	1.41e-01	7.71e-01
REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX	9	3.61e-01	-1.76e-01	7.71e-01
REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION	32	3.63e-01	9.29e-02	7.73e-01
REACTOME ELASTIC FIBRE FORMATION	44	3.63e-01	7.92e-02	7.73e-01
REACTOME FREE FATTY ACIDS REGULATE INSULIN SECRETION	10	3.64e-01	1.66e-01	7.73e-01
REACTOME VIRAL MESSENGER RNA SYNTHESIS	44	3.65e-01	-7.90e-02	7.73e-01
REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	30	3.65e-01	-9.56e-02	7.73e-01
REACTOME PREVENTION OF PHAGOSOMAL LYSOSOMAL FUSION	9	3.66e-01	-1.74e-01	7.73e-01
REACTOME NS1 MEDIATED EFFECTS ON HOST PATHWAYS	41	3.66e-01	-8.16e-02	7.73e-01
REACTOME SYNTHESIS OF DIPHTHAMIDE EEF2	8	3.66e-01	-1.84e-01	7.73e-01
REACTOME NUCLEAR PORE COMPLEX NPC DISASSEMBLY	36	3.66e-01	-8.70e-02	7.73e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL	15	3.68e-01	1.34e-01	7.74e-01
REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION	8	3.68e-01	1.84e-01	7.74e-01
REACTOME GAP JUNCTION ASSEMBLY	36	3.69e-01	8.66e-02	7.74e-01
REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	13	3.69e-01	-1.44e-01	7.74e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG	7	3.69e-01	1.96e-01	7.74e-01
REACTOME ERBB2 ACTIVATES PTK6 SIGNALING	13	3.70e-01	-1.44e-01	7.74e-01
REACTOME SCAVENGING OF HEME FROM PLASMA	13	3.71e-01	1.43e-01	7.76e-01
REACTOME NCAM1 INTERACTIONS	41	3.72e-01	8.05e-02	7.76e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES	49	3.73e-01	-7.35e-02	7.76e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST	18	3.73e-01	-1.21e-01	7.76e-01
REACTOME LAGGING STRAND SYNTHESIS	19	3.74e-01	-1.18e-01	7.76e-01
REACTOME DISEASES OF METABOLISM	237	3.74e-01	3.35e-02	7.76e-01
REACTOME RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES TREGS	9	3.75e-01	-1.71e-01	7.76e-01
REACTOME LOSS OF FUNCTION OF SMAD2 3 IN CANCER	7	3.76e-01	-1.93e-01	7.76e-01
REACTOME ACTIVATION OF CASPASES THROUGH APOPTOSOME MEDIATED CLEAVAGE	5	3.76e-01	-2.29e-01	7.76e-01
REACTOME PROCESSING OF INTRONLESS PRE MRNAS	19	3.76e-01	-1.17e-01	7.76e-01
REACTOME HORMONE LIGAND BINDING RECEPTORS	12	3.76e-01	1.48e-01	7.76e-01
REACTOME ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM	12	3.76e-01	1.47e-01	7.76e-01
REACTOME RUNX3 REGULATES YAP1 MEDIATED TRANSCRIPTION	8	3.77e-01	1.80e-01	7.76e-01
REACTOME NEF MEDIATED CD4 DOWN REGULATION	9	3.78e-01	1.70e-01	7.76e-01
REACTOME DIGESTION AND ABSORPTION	22	3.78e-01	1.09e-01	7.76e-01
REACTOME RORA ACTIVATES GENE EXPRESSION	17	3.79e-01	1.23e-01	7.77e-01
REACTOME RAC1 GTPASE CYCLE	172	3.80e-01	3.88e-02	7.78e-01
REACTOME MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS	13	3.80e-01	-1.41e-01	7.78e-01
REACTOME MOLYBDENUM COFACTOR BIOSYNTHESIS	6	3.81e-01	-2.06e-01	7.78e-01
REACTOME NOD1 2 SIGNALING PATHWAY	33	3.81e-01	-8.81e-02	7.78e-01
REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS	5	3.81e-01	2.26e-01	7.78e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS	5	3.82e-01	-2.26e-01	7.78e-01
REACTOME ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA	5	3.84e-01	-2.25e-01	7.80e-01
REACTOME SIGNALING BY KIT IN DISEASE	20	3.84e-01	-1.12e-01	7.81e-01
REACTOME MET ACTIVATES PI3K AKT SIGNALING	6	3.87e-01	-2.04e-01	7.82e-01
REACTOME BETA OXIDATION OF BUTANOYL COA TO ACETYL COA	5	3.87e-01	2.24e-01	7.82e-01
REACTOME THE PHOTOTRANSDUCTION CASCADE	32	3.87e-01	8.84e-02	7.82e-01
REACTOME PI 3K CASCADE FGFR4	19	3.88e-01	1.14e-01	7.82e-01
REACTOME G2 PHASE	5	3.88e-01	-2.23e-01	7.82e-01
REACTOME MITOCHONDRIAL BIOGENESIS	87	3.89e-01	-5.35e-02	7.82e-01
REACTOME SUMOYLATION OF UBIQUITINYLATION PROTEINS	39	3.89e-01	-7.97e-02	7.82e-01
REACTOME SIALIC ACID METABOLISM	33	3.89e-01	8.66e-02	7.82e-01
REACTOME NUCLEAR ENVELOPE BREAKDOWN	52	3.89e-01	-6.90e-02	7.82e-01
REACTOME PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1	9	3.90e-01	-1.66e-01	7.82e-01
REACTOME METABOLISM OF INGESTED SEMET SEC MESEC INTO H2SE	7	3.90e-01	1.88e-01	7.82e-01
REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	129	3.91e-01	-4.37e-02	7.83e-01
REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R	52	3.93e-01	6.84e-02	7.86e-01
REACTOME SUMOYLATION OF SUMOYLATION PROTEINS	35	3.94e-01	-8.33e-02	7.86e-01
REACTOME REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS	11	3.94e-01	1.48e-01	7.86e-01
REACTOME AUTOPHAGY	144	3.95e-01	-4.10e-02	7.87e-01
REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	19	3.96e-01	-1.13e-01	7.87e-01
REACTOME ACTIVATION OF AMPK DOWNSTREAM OF NMDARS	28	3.96e-01	9.27e-02	7.87e-01
REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	52	3.98e-01	6.77e-02	7.91e-01
REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	15	4.00e-01	1.26e-01	7.92e-01
REACTOME CIRCADIAN CLOCK	68	4.00e-01	5.90e-02	7.92e-01
REACTOME ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING	23	4.01e-01	-1.01e-01	7.92e-01
REACTOME CATION COUPLED CHLORIDE COTRANSPORTERS	7	4.01e-01	1.83e-01	7.92e-01
REACTOME POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION	27	4.01e-01	-9.34e-02	7.92e-01
REACTOME FATTY ACYL COA BIOSYNTHESIS	36	4.04e-01	8.04e-02	7.94e-01
REACTOME TRNA AMINOACYLATION	40	4.04e-01	-7.62e-02	7.94e-01
REACTOME CELL JUNCTION ORGANIZATION	89	4.05e-01	5.11e-02	7.94e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1	20	4.05e-01	-1.08e-01	7.94e-01
REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB	5	4.05e-01	2.15e-01	7.94e-01
REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	30	4.06e-01	8.76e-02	7.94e-01
REACTOME DISEASES OF MISMATCH REPAIR MMR	5	4.07e-01	-2.14e-01	7.94e-01
REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	48	4.07e-01	6.92e-02	7.94e-01
REACTOME SENSING OF DNA DOUBLE STRAND BREAKS	6	4.07e-01	-1.95e-01	7.94e-01
REACTOME INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS	37	4.07e-01	-7.87e-02	7.94e-01
REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	23	4.08e-01	9.97e-02	7.94e-01
REACTOME RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS	9	4.08e-01	-1.59e-01	7.94e-01
REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS	15	4.09e-01	-1.23e-01	7.94e-01
REACTOME SIGNALING BY ERBB2 IN CANCER	26	4.10e-01	-9.34e-02	7.95e-01
REACTOME TAK1 DEPENDENT IKK AND NF KAPPA B ACTIVATION	41	4.10e-01	-7.43e-02	7.95e-01
REACTOME PI3K EVENTS IN ERBB2 SIGNALING	16	4.11e-01	-1.19e-01	7.95e-01
REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE	71	4.11e-01	5.64e-02	7.95e-01
REACTOME IRF3 MEDIATED INDUCTION OF TYPE I IFN	13	4.13e-01	1.31e-01	7.95e-01
REACTOME GLYCOGEN STORAGE DISEASES	15	4.13e-01	-1.22e-01	7.95e-01
REACTOME GPER1 SIGNALING	45	4.13e-01	7.05e-02	7.95e-01
REACTOME TELOMERE C STRAND SYNTHESIS INITIATION	12	4.13e-01	-1.36e-01	7.95e-01
REACTOME ACTIVATION OF SMO	18	4.14e-01	1.11e-01	7.95e-01
REACTOME CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION	24	4.14e-01	-9.62e-02	7.95e-01
REACTOME SHC MEDIATED CASCADE FGFR4	19	4.16e-01	1.08e-01	7.95e-01
REACTOME COPII MEDIATED VESICLE TRANSPORT	66	4.16e-01	-5.80e-02	7.95e-01
REACTOME RUNX2 REGULATES CHONDROCYTE MATURATION	5	4.16e-01	2.10e-01	7.95e-01
REACTOME ATTACHMENT AND ENTRY	16	4.16e-01	1.17e-01	7.95e-01
REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF	53	4.17e-01	6.45e-02	7.95e-01
REACTOME HDR THROUGH MMEJ ALT NHEJ	12	4.17e-01	-1.35e-01	7.95e-01
REACTOME DNA STRAND ELONGATION	31	4.17e-01	-8.42e-02	7.95e-01
REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	16	4.20e-01	1.17e-01	7.98e-01
REACTOME ASPARTATE AND ASPARAGINE METABOLISM	11	4.21e-01	1.40e-01	7.99e-01
REACTOME TACHYKININ RECEPTORS BIND TACHYKININS	5	4.21e-01	-2.08e-01	8.00e-01
REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	15	4.22e-01	1.20e-01	8.00e-01
REACTOME NUCLEAR ENVELOPE NE REASSEMBLY	74	4.23e-01	-5.39e-02	8.00e-01
REACTOME RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION	22	4.23e-01	9.87e-02	8.00e-01
REACTOME INFECTION WITH MYCOBACTERIUM TUBERCULOSIS	25	4.23e-01	-9.25e-02	8.00e-01
REACTOME RUNX3 REGULATES NOTCH SIGNALING	13	4.24e-01	-1.28e-01	8.01e-01
REACTOME RHOT1 GTPASE CYCLE	5	4.26e-01	-2.06e-01	8.03e-01
REACTOME SYNTHESIS OF PA	38	4.26e-01	-7.46e-02	8.03e-01
REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	69	4.27e-01	5.53e-02	8.03e-01
REACTOME RAB GERANYLGERANYLATION	57	4.29e-01	-6.06e-02	8.04e-01
REACTOME SULFUR AMINO ACID METABOLISM	27	4.29e-01	-8.80e-02	8.04e-01
REACTOME REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO	10	4.29e-01	-1.44e-01	8.05e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	34	4.30e-01	7.81e-02	8.06e-01
REACTOME NEF AND SIGNAL TRANSDUCTION	8	4.32e-01	-1.61e-01	8.06e-01
REACTOME EPHRIN SIGNALING	17	4.32e-01	1.10e-01	8.06e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING	25	4.34e-01	9.04e-02	8.06e-01
REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	14	4.34e-01	-1.21e-01	8.06e-01
REACTOME TRANSPORT OF RCBL WITHIN THE BODY	8	4.34e-01	1.60e-01	8.06e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1	16	4.35e-01	-1.13e-01	8.06e-01
REACTOME RHOBTB1 GTPASE CYCLE	22	4.35e-01	9.62e-02	8.06e-01
REACTOME REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION	9	4.35e-01	-1.50e-01	8.06e-01
REACTOME NEPHRIN FAMILY INTERACTIONS	22	4.36e-01	-9.60e-02	8.06e-01
REACTOME SIGNALING BY ACTIVIN	15	4.36e-01	-1.16e-01	8.06e-01
REACTOME PARASITE INFECTION	57	4.36e-01	-5.97e-02	8.06e-01
REACTOME SIGNALING BY RNF43 MUTANTS	8	4.37e-01	1.59e-01	8.07e-01
REACTOME FREE FATTY ACID RECEPTORS	5	4.38e-01	2.00e-01	8.09e-01
REACTOME EPH EPHRIN MEDIATED REPULSION OF CELLS	50	4.39e-01	6.33e-02	8.09e-01
REACTOME 2 LTR CIRCLE FORMATION	7	4.39e-01	-1.69e-01	8.09e-01
REACTOME THE ACTIVATION OF ARYLSULFATASES	8	4.41e-01	-1.57e-01	8.09e-01
REACTOME ZINC TRANSPORTERS	15	4.41e-01	-1.15e-01	8.09e-01
REACTOME SIGNALING BY MRAS COMPLEX MUTANTS	7	4.42e-01	-1.68e-01	8.09e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION	45	4.42e-01	-6.63e-02	8.09e-01
REACTOME NEUROFASCIN INTERACTIONS	6	4.43e-01	1.81e-01	8.10e-01
REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS	43	4.45e-01	6.73e-02	8.14e-01
REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS	8	4.46e-01	-1.56e-01	8.14e-01
REACTOME ARYL HYDROCARBON RECEPTOR SIGNALLING	6	4.47e-01	-1.79e-01	8.15e-01
REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING	32	4.47e-01	7.76e-02	8.15e-01
REACTOME HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS	7	4.50e-01	-1.65e-01	8.19e-01
REACTOME NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10	12	4.51e-01	-1.26e-01	8.19e-01
REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	122	4.52e-01	-3.95e-02	8.19e-01
REACTOME INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE	20	4.52e-01	-9.72e-02	8.19e-01
REACTOME ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA	9	4.52e-01	1.45e-01	8.19e-01
REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES	14	4.53e-01	1.16e-01	8.20e-01
REACTOME SIGNALING BY ERBB2 ECD MUTANTS	16	4.54e-01	-1.08e-01	8.20e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE	5	4.54e-01	1.93e-01	8.20e-01
REACTOME FCERI MEDIATED MAPK ACTIVATION	32	4.56e-01	-7.61e-02	8.21e-01
REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	45	4.56e-01	6.42e-02	8.21e-01
REACTOME P2Y RECEPTORS	9	4.57e-01	1.43e-01	8.21e-01
REACTOME SIGNALING BY NOTCH3	48	4.57e-01	-6.21e-02	8.21e-01
REACTOME CLATHRIN MEDIATED ENDOCYTOSIS	139	4.58e-01	-3.65e-02	8.21e-01
REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION	26	4.58e-01	-8.41e-02	8.21e-01
REACTOME ORGANIC ANION TRANSPORTERS	10	4.58e-01	-1.35e-01	8.21e-01
REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	17	4.60e-01	1.03e-01	8.22e-01
REACTOME RHOBTB3 ATPASE CYCLE	8	4.61e-01	1.51e-01	8.22e-01
REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	14	4.61e-01	-1.14e-01	8.22e-01
REACTOME MAPK3 ERK1 ACTIVATION	10	4.61e-01	-1.35e-01	8.22e-01
REACTOME INACTIVATION OF CDC42 AND RAC1	8	4.61e-01	1.50e-01	8.22e-01
REACTOME SODIUM CALCIUM EXCHANGERS	11	4.62e-01	1.28e-01	8.22e-01
REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS	68	4.64e-01	-5.13e-02	8.22e-01
REACTOME HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR IN THE PRESENCE OF LIGAND	55	4.65e-01	-5.70e-02	8.22e-01
REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	21	4.65e-01	-9.20e-02	8.22e-01
REACTOME MRNA EDITING	10	4.66e-01	-1.33e-01	8.22e-01
REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN	37	4.66e-01	6.93e-02	8.22e-01
REACTOME MISMATCH REPAIR	15	4.66e-01	-1.09e-01	8.22e-01
REACTOME MICRORNA MIRNA BIOGENESIS	25	4.67e-01	-8.41e-02	8.22e-01
REACTOME INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL	14	4.67e-01	-1.12e-01	8.22e-01
REACTOME CALNEXIN CALRETICULIN CYCLE	26	4.67e-01	-8.25e-02	8.22e-01
REACTOME SMOOTH MUSCLE CONTRACTION	43	4.67e-01	6.41e-02	8.22e-01
REACTOME RAS PROCESSING	22	4.67e-01	-8.95e-02	8.22e-01
REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	32	4.69e-01	-7.40e-02	8.24e-01
REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING	33	4.70e-01	7.27e-02	8.25e-01
REACTOME PROTEIN METHYLATION	17	4.70e-01	-1.01e-01	8.25e-01
REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY	25	4.71e-01	-8.34e-02	8.25e-01
REACTOME GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER	25	4.72e-01	-8.31e-02	8.25e-01
REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	12	4.72e-01	1.20e-01	8.25e-01
REACTOME CRMPS IN SEMA3A SIGNALING	15	4.73e-01	1.07e-01	8.25e-01
REACTOME MYOGENESIS	29	4.74e-01	7.68e-02	8.25e-01
REACTOME TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA	36	4.74e-01	-6.90e-02	8.25e-01
REACTOME MRNA CAPPING	28	4.74e-01	-7.82e-02	8.25e-01
REACTOME REGULATION OF IFNA IFNB SIGNALING	23	4.74e-01	-8.62e-02	8.25e-01
REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	32	4.79e-01	7.23e-02	8.32e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS	15	4.81e-01	-1.05e-01	8.35e-01
REACTOME ER TO GOLGI ANTEROGRADE TRANSPORT	152	4.82e-01	-3.31e-02	8.35e-01
REACTOME IRON UPTAKE AND TRANSPORT	56	4.82e-01	-5.43e-02	8.35e-01
REACTOME ETHANOL OXIDATION	12	4.83e-01	-1.17e-01	8.36e-01
REACTOME TP53 REGULATES METABOLIC GENES	81	4.84e-01	-4.50e-02	8.36e-01
REACTOME DEGRADATION OF CYSTEINE AND HOMOCYSTEINE	15	4.84e-01	-1.04e-01	8.36e-01
REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	9	4.87e-01	1.34e-01	8.40e-01
REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	44	4.87e-01	-6.05e-02	8.40e-01
REACTOME RHOV GTPASE CYCLE	36	4.89e-01	6.67e-02	8.40e-01
REACTOME ATORVASTATIN ADME	9	4.89e-01	1.33e-01	8.40e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM	38	4.89e-01	6.48e-02	8.41e-01
REACTOME PEROXISOMAL LIPID METABOLISM	28	4.91e-01	-7.52e-02	8.42e-01
REACTOME PLATELET HOMEOSTASIS	85	4.91e-01	4.32e-02	8.42e-01
REACTOME METABOLISM OF STEROIDS	150	4.92e-01	3.25e-02	8.42e-01
REACTOME BILE ACID AND BILE SALT METABOLISM	45	4.92e-01	5.91e-02	8.42e-01
REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL	12	4.93e-01	-1.14e-01	8.43e-01
REACTOME LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME	11	4.94e-01	1.19e-01	8.43e-01
REACTOME ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY	10	4.94e-01	1.25e-01	8.43e-01
REACTOME EXTRA NUCLEAR ESTROGEN SIGNALING	74	4.95e-01	-4.59e-02	8.43e-01
REACTOME CYTOPROTECTION BY HMOX1	59	4.95e-01	-5.13e-02	8.43e-01
REACTOME ALPHA DEFENSINS	6	4.97e-01	1.60e-01	8.44e-01
REACTOME BH3 ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI APOPTOTIC BCL 2 MEMBERS	9	4.98e-01	-1.30e-01	8.46e-01
REACTOME INLA MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS	9	5.02e-01	-1.29e-01	8.50e-01
REACTOME CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA	63	5.02e-01	-4.89e-02	8.50e-01
REACTOME VITAMIN B2 RIBOFLAVIN METABOLISM	7	5.02e-01	1.47e-01	8.50e-01
REACTOME HYALURONAN UPTAKE AND DEGRADATION	12	5.03e-01	-1.12e-01	8.51e-01
REACTOME ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA	15	5.06e-01	-9.92e-02	8.52e-01
REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	24	5.06e-01	7.84e-02	8.52e-01
REACTOME DOWNREGULATION OF ERBB2 SIGNALING	29	5.06e-01	-7.13e-02	8.52e-01
REACTOME NTRK2 ACTIVATES RAC1	5	5.06e-01	1.72e-01	8.52e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR4	26	5.06e-01	7.53e-02	8.52e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH CDK5	6	5.08e-01	1.56e-01	8.53e-01
REACTOME SPERM MOTILITY AND TAXES	9	5.09e-01	-1.27e-01	8.54e-01
REACTOME MATURATION OF SARS COV 2 NUCLEOPROTEIN	15	5.11e-01	9.79e-02	8.56e-01
REACTOME REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA	15	5.12e-01	-9.78e-02	8.56e-01
REACTOME SIGNAL ATTENUATION	10	5.13e-01	1.20e-01	8.56e-01
REACTOME SYNTHESIS OF GDP MANNOSE	5	5.13e-01	-1.69e-01	8.56e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH RAS	9	5.14e-01	-1.26e-01	8.56e-01
REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	16	5.14e-01	-9.42e-02	8.56e-01
REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	20	5.15e-01	-8.42e-02	8.56e-01
REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	11	5.15e-01	-1.13e-01	8.56e-01
REACTOME INTERLEUKIN 1 FAMILY SIGNALING	146	5.15e-01	-3.12e-02	8.56e-01
REACTOME CILIUM ASSEMBLY	190	5.17e-01	-2.73e-02	8.56e-01
REACTOME SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX	15	5.17e-01	9.66e-02	8.56e-01
REACTOME FGFR2 ALTERNATIVE SPLICING	27	5.17e-01	-7.20e-02	8.56e-01
REACTOME PROTEIN REPAIR	6	5.18e-01	-1.53e-01	8.56e-01
REACTOME LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX	5	5.19e-01	1.67e-01	8.56e-01
REACTOME SYNTHESIS OF PE	13	5.20e-01	-1.03e-01	8.56e-01
REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING	28	5.21e-01	7.01e-02	8.56e-01
REACTOME LTC4 CYSLTR MEDIATED IL4 PRODUCTION	6	5.23e-01	1.51e-01	8.56e-01
REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL	13	5.23e-01	1.02e-01	8.56e-01
REACTOME INITIAL TRIGGERING OF COMPLEMENT	21	5.25e-01	8.01e-02	8.56e-01
REACTOME RHO GTPASES ACTIVATE PAKS	19	5.25e-01	8.42e-02	8.56e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FYN	7	5.26e-01	1.39e-01	8.56e-01
REACTOME CYTOCHROME C MEDIATED APOPTOTIC RESPONSE	12	5.26e-01	-1.06e-01	8.56e-01
REACTOME REGULATION OF NPAS4 GENE EXPRESSION	13	5.26e-01	-1.01e-01	8.56e-01
REACTOME STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES	16	5.27e-01	9.14e-02	8.56e-01
REACTOME BIOLOGICAL OXIDATIONS	210	5.27e-01	-2.53e-02	8.56e-01
REACTOME PHASE II CONJUGATION OF COMPOUNDS	102	5.27e-01	-3.63e-02	8.56e-01
REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS	5	5.27e-01	1.63e-01	8.56e-01
REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	24	5.27e-01	-7.46e-02	8.56e-01
REACTOME DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE	30	5.27e-01	6.67e-02	8.56e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS	6	5.27e-01	1.49e-01	8.56e-01
REACTOME GROWTH HORMONE RECEPTOR SIGNALING	24	5.27e-01	7.46e-02	8.56e-01
REACTOME UREA CYCLE	9	5.28e-01	-1.22e-01	8.56e-01
REACTOME RHOH GTPASE CYCLE	37	5.29e-01	-5.98e-02	8.56e-01
REACTOME AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY	8	5.29e-01	1.28e-01	8.56e-01
REACTOME RUNX2 REGULATES BONE DEVELOPMENT	29	5.29e-01	6.75e-02	8.56e-01
REACTOME DEFECTIVE GALNT3 CAUSES HFTC	16	5.30e-01	9.07e-02	8.56e-01
REACTOME TRANSPORT OF NUCLEOTIDE SUGARS	8	5.30e-01	1.28e-01	8.56e-01
REACTOME COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC	52	5.31e-01	5.03e-02	8.56e-01
REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE	93	5.32e-01	-3.75e-02	8.56e-01
REACTOME MATURATION OF SARS COV 1 SPIKE PROTEIN	5	5.33e-01	-1.61e-01	8.56e-01
REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	13	5.33e-01	9.98e-02	8.56e-01
REACTOME XENOBIOTICS	22	5.33e-01	7.67e-02	8.56e-01
REACTOME ROBO RECEPTORS BIND AKAP5	9	5.34e-01	1.20e-01	8.56e-01
REACTOME AMINO ACID CONJUGATION	9	5.34e-01	-1.20e-01	8.56e-01
REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	16	5.34e-01	8.97e-02	8.56e-01
REACTOME GLUCOSE METABOLISM	90	5.35e-01	3.78e-02	8.56e-01
REACTOME CALCINEURIN ACTIVATES NFAT	9	5.35e-01	-1.19e-01	8.56e-01
REACTOME NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS	22	5.37e-01	-7.61e-02	8.56e-01
REACTOME PROLONGED ERK ACTIVATION EVENTS	14	5.37e-01	9.53e-02	8.56e-01
REACTOME SUMOYLATION	179	5.37e-01	-2.67e-02	8.56e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX IN CANCER	8	5.38e-01	-1.26e-01	8.56e-01
REACTOME NUCLEAR SIGNALING BY ERBB4	32	5.38e-01	-6.29e-02	8.56e-01
REACTOME EFFECTS OF PIP2 HYDROLYSIS	26	5.38e-01	6.97e-02	8.56e-01
REACTOME RHO GTPASES ACTIVATE NADPH OXIDASES	21	5.40e-01	7.73e-02	8.56e-01
REACTOME DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15	8	5.40e-01	1.25e-01	8.56e-01
REACTOME FGFR2B LIGAND BINDING AND ACTIVATION	10	5.40e-01	1.12e-01	8.56e-01
REACTOME LRR FLII INTERACTING PROTEIN 1 LRRFIP1 ACTIVATES TYPE I IFN PRODUCTION	5	5.41e-01	-1.58e-01	8.56e-01
REACTOME PEPTIDE HORMONE METABOLISM	84	5.41e-01	3.86e-02	8.56e-01
REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	9	5.42e-01	-1.17e-01	8.56e-01
REACTOME HEDGEHOG ON STATE	85	5.43e-01	-3.82e-02	8.56e-01
REACTOME SODIUM PROTON EXCHANGERS	7	5.45e-01	1.32e-01	8.56e-01
REACTOME RND2 GTPASE CYCLE	42	5.45e-01	5.40e-02	8.56e-01
REACTOME PI3K EVENTS IN ERBB4 SIGNALING	10	5.45e-01	-1.11e-01	8.56e-01
REACTOME PHYSIOLOGICAL FACTORS	14	5.45e-01	9.34e-02	8.56e-01
REACTOME PHOSPHOLIPID METABOLISM	201	5.46e-01	2.47e-02	8.56e-01
REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	20	5.46e-01	7.80e-02	8.56e-01
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION	250	5.47e-01	-2.21e-02	8.56e-01
REACTOME TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS	36	5.47e-01	5.79e-02	8.56e-01
REACTOME SIGNALING BY ERYTHROPOIETIN	25	5.48e-01	-6.95e-02	8.56e-01
REACTOME HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS	9	5.48e-01	-1.16e-01	8.56e-01
REACTOME REGULATION OF BACH1 ACTIVITY	11	5.49e-01	-1.04e-01	8.56e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS	9	5.49e-01	1.15e-01	8.56e-01
REACTOME ERBB2 REGULATES CELL MOTILITY	15	5.49e-01	-8.94e-02	8.56e-01
REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	91	5.49e-01	3.63e-02	8.56e-01
REACTOME SIGNALING BY FGFR3	39	5.50e-01	5.53e-02	8.56e-01
REACTOME SARS COV 2 TARGETS PDZ PROTEINS IN CELL CELL JUNCTION	5	5.50e-01	-1.54e-01	8.56e-01
REACTOME SIGNALING BY FGFR4 IN DISEASE	11	5.51e-01	1.04e-01	8.56e-01
REACTOME DEX H BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION	7	5.51e-01	-1.30e-01	8.56e-01
REACTOME ARMS MEDIATED ACTIVATION	7	5.51e-01	1.30e-01	8.56e-01
REACTOME SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS	16	5.52e-01	8.59e-02	8.57e-01
REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	11	5.53e-01	-1.03e-01	8.57e-01
REACTOME REGULATION OF FZD BY UBIQUITINATION	21	5.55e-01	-7.45e-02	8.57e-01
REACTOME ION CHANNEL TRANSPORT	172	5.55e-01	2.61e-02	8.57e-01
REACTOME P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1	6	5.55e-01	1.39e-01	8.57e-01
REACTOME GP1B IX V ACTIVATION SIGNALLING	11	5.55e-01	1.03e-01	8.57e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH PI3K	7	5.56e-01	-1.28e-01	8.57e-01
REACTOME RELEASE OF HH NP FROM THE SECRETING CELL	8	5.57e-01	1.20e-01	8.57e-01
REACTOME DIGESTION OF DIETARY CARBOHYDRATE	6	5.57e-01	1.38e-01	8.57e-01
REACTOME INSULIN RECEPTOR RECYCLING	29	5.57e-01	6.30e-02	8.57e-01
REACTOME VITAMIN D CALCIFEROL METABOLISM	12	5.59e-01	-9.75e-02	8.58e-01
REACTOME HS GAG DEGRADATION	19	5.59e-01	-7.75e-02	8.58e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH CDC42	19	5.59e-01	-7.75e-02	8.58e-01
REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	23	5.60e-01	7.02e-02	8.58e-01
REACTOME PROTON COUPLED MONOCARBOXYLATE TRANSPORT	6	5.60e-01	-1.37e-01	8.58e-01
REACTOME PTK6 EXPRESSION	5	5.61e-01	-1.50e-01	8.58e-01
REACTOME WAX AND PLASMALOGEN BIOSYNTHESIS	5	5.61e-01	-1.50e-01	8.58e-01
REACTOME EGFR TRANSACTIVATION BY GASTRIN	9	5.62e-01	-1.12e-01	8.58e-01
REACTOME CHYLOMICRON CLEARANCE	5	5.63e-01	1.49e-01	8.59e-01
REACTOME PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING	5	5.64e-01	-1.49e-01	8.59e-01
REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS	18	5.64e-01	7.85e-02	8.59e-01
REACTOME SIGNALING BY FGFR1	49	5.65e-01	4.76e-02	8.59e-01
REACTOME GLYCOLYSIS	70	5.65e-01	3.98e-02	8.59e-01
REACTOME MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS	17	5.68e-01	-8.01e-02	8.61e-01
REACTOME CREATINE METABOLISM	9	5.68e-01	1.10e-01	8.61e-01
REACTOME SIGNALING BY PTK6	54	5.69e-01	-4.48e-02	8.61e-01
REACTOMEMATURATION OF SARS COV 1 NUCLEOPROTEIN	11	5.69e-01	9.92e-02	8.61e-01
REACTOME SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS	12	5.70e-01	-9.47e-02	8.61e-01
REACTOME ECM PROTEOGLYCANS	73	5.70e-01	3.84e-02	8.61e-01
REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES	78	5.70e-01	3.72e-02	8.61e-01
REACTOME MET ACTIVATES RAS SIGNALING	11	5.70e-01	-9.88e-02	8.61e-01
REACTOME LIGAND RECEPTOR INTERACTIONS	8	5.71e-01	1.16e-01	8.62e-01
REACTOME UPTAKE AND ACTIONS OF BACTERIAL TOXINS	28	5.72e-01	-6.17e-02	8.62e-01
REACTOME METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION	15	5.73e-01	8.41e-02	8.62e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES	10	5.73e-01	-1.03e-01	8.62e-01
REACTOME ORGANIC ANION TRANSPORT	5	5.74e-01	1.45e-01	8.62e-01
REACTOME ACTIVATION OF RAC1	12	5.75e-01	9.35e-02	8.63e-01
REACTOME METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS	122	5.77e-01	2.93e-02	8.64e-01
REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	22	5.77e-01	6.87e-02	8.64e-01
REACTOME POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE	25	5.79e-01	-6.41e-02	8.66e-01
REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	8	5.79e-01	-1.13e-01	8.66e-01
REACTOME INTEGRIN SIGNALING	27	5.81e-01	-6.14e-02	8.67e-01
REACTOME ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION	16	5.81e-01	-7.97e-02	8.67e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN	13	5.81e-01	8.83e-02	8.67e-01
REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS	16	5.82e-01	7.95e-02	8.67e-01
REACTOME DIGESTION OF DIETARY LIPID	7	5.83e-01	1.20e-01	8.67e-01
REACTOME RNA POLYMERASE II PRE TRANSCRIPTION EVENTS	77	5.83e-01	-3.62e-02	8.67e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING	6	5.84e-01	-1.29e-01	8.68e-01
REACTOME NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	11	5.85e-01	-9.52e-02	8.68e-01
REACTOME FIBRONECTIN MATRIX FORMATION	6	5.86e-01	-1.28e-01	8.68e-01
REACTOME SHC1 EVENTS IN ERBB2 SIGNALING	22	5.86e-01	-6.71e-02	8.68e-01
REACTOME ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT	23	5.87e-01	6.55e-02	8.68e-01
REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES	7	5.87e-01	1.19e-01	8.68e-01
REACTOME IKBA VARIANT LEADS TO EDA ID	6	5.87e-01	1.28e-01	8.68e-01
REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	15	5.88e-01	8.08e-02	8.68e-01
REACTOME RHOJ GTPASE CYCLE	51	5.88e-01	4.38e-02	8.68e-01
REACTOME RAB REGULATION OF TRAFFICKING	110	5.89e-01	2.98e-02	8.68e-01
REACTOME ADHERENS JUNCTIONS INTERACTIONS	33	5.93e-01	-5.38e-02	8.71e-01
REACTOME SUMOYLATION OF DNA REPLICATION PROTEINS	46	5.93e-01	-4.56e-02	8.71e-01
REACTOME SELECTIVE AUTOPHAGY	79	5.94e-01	-3.47e-02	8.71e-01
REACTOME SHC RELATED EVENTS TRIGGERED BY IGF1R	9	5.94e-01	-1.03e-01	8.71e-01
REACTOME SIGNALING BY NTRK3 TRKC	17	5.94e-01	-7.46e-02	8.71e-01
REACTOME DERMATAN SULFATE BIOSYNTHESIS	10	5.95e-01	9.71e-02	8.71e-01
REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES	77	5.96e-01	3.50e-02	8.71e-01
REACTOME IRAK4 DEFICIENCY TLR2 4	17	5.97e-01	-7.42e-02	8.71e-01
REACTOME GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION	7	5.97e-01	1.15e-01	8.71e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES	33	5.97e-01	-5.32e-02	8.71e-01
REACTOME COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING	32	5.98e-01	-5.38e-02	8.71e-01
REACTOME HDL REMODELING	10	5.98e-01	-9.62e-02	8.71e-01
REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	16	5.98e-01	-7.60e-02	8.71e-01
REACTOME SULFIDE OXIDATION TO SULFATE	6	5.99e-01	1.24e-01	8.71e-01
REACTOME SMALL INTERFERING RNA SIRNA BIOGENESIS	9	5.99e-01	1.01e-01	8.71e-01
REACTOME SIGNALING BY ERBB2	50	6.00e-01	-4.29e-02	8.71e-01
REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS	6	6.01e-01	1.23e-01	8.73e-01
REACTOME SIGNALING BY HIPPO	19	6.03e-01	-6.89e-02	8.73e-01
REACTOME SOS MEDIATED SIGNALLING	7	6.03e-01	1.13e-01	8.73e-01
REACTOME CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE	49	6.04e-01	-4.29e-02	8.73e-01
REACTOME SUMOYLATION OF TRANSCRIPTION FACTORS	20	6.04e-01	-6.70e-02	8.73e-01
REACTOME RHOG GTPASE CYCLE	71	6.04e-01	3.56e-02	8.73e-01
REACTOME SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER	15	6.05e-01	7.71e-02	8.74e-01
REACTOME SIGNALING BY LRP5 MUTANTS	6	6.06e-01	-1.22e-01	8.74e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY	19	6.06e-01	6.83e-02	8.74e-01
REACTOME GERM LAYER FORMATION AT GASTRULATION	17	6.07e-01	-7.20e-02	8.74e-01
REACTOME CHOLESTEROL BIOSYNTHESIS	25	6.07e-01	5.94e-02	8.74e-01
REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III	31	6.08e-01	5.32e-02	8.74e-01
REACTOME DISEASES OF IMMUNE SYSTEM	29	6.09e-01	-5.49e-02	8.75e-01
REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	32	6.10e-01	5.21e-02	8.76e-01
REACTOME DISINHIBITION OF SNARE FORMATION	5	6.11e-01	-1.31e-01	8.76e-01
REACTOME CITRIC ACID CYCLE TCA CYCLE	21	6.12e-01	-6.40e-02	8.76e-01
REACTOME MATURATION OF SARS COV 2 SPIKE PROTEIN	35	6.13e-01	4.94e-02	8.77e-01
REACTOME SIGNALING BY MAPK MUTANTS	6	6.15e-01	1.18e-01	8.79e-01
REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION	6	6.16e-01	-1.18e-01	8.79e-01
REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	45	6.16e-01	4.32e-02	8.79e-01
REACTOME GLYCOGEN SYNTHESIS	13	6.16e-01	-8.03e-02	8.79e-01
REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	29	6.17e-01	-5.36e-02	8.79e-01
REACTOME RESPONSE OF MTB TO PHAGOCYTOSIS	22	6.18e-01	-6.15e-02	8.79e-01
REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC	198	6.18e-01	-2.05e-02	8.79e-01
REACTOME CELL CELL JUNCTION ORGANIZATION	64	6.19e-01	-3.60e-02	8.79e-01
REACTOME PROPIONYL COA CATABOLISM	5	6.19e-01	-1.28e-01	8.79e-01
REACTOME GLYCEROPHOSPHOLIPID CATABOLISM	7	6.20e-01	-1.08e-01	8.79e-01
REACTOME NECTIN NECL TRANS HETERODIMERIZATION	7	6.21e-01	-1.08e-01	8.79e-01
REACTOME ABACAVIR TRANSMEMBRANE TRANSPORT	5	6.21e-01	1.28e-01	8.79e-01
REACTOME INOSITOL PHOSPHATE METABOLISM	45	6.21e-01	4.26e-02	8.79e-01
REACTOME SEMA4D IN SEMAPHORIN SIGNALING	24	6.22e-01	5.81e-02	8.80e-01
REACTOME GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	34	6.23e-01	-4.88e-02	8.80e-01
REACTOME NUCLEOTIDE CATABOLISM	35	6.24e-01	-4.79e-02	8.80e-01
REACTOME G PROTEIN BETA GAMMA SIGNALLING	30	6.24e-01	5.17e-02	8.80e-01
REACTOME G ALPHA Z SIGNALLING EVENTS	48	6.24e-01	-4.08e-02	8.80e-01
REACTOME RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION	6	6.25e-01	-1.15e-01	8.80e-01
REACTOME ALPHA OXIDATION OF PHYTANATE	6	6.26e-01	-1.15e-01	8.81e-01
REACTOME SPHINGOLIPID METABOLISM	84	6.27e-01	3.07e-02	8.81e-01
REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING	29	6.28e-01	5.20e-02	8.82e-01
REACTOME FCGR ACTIVATION	11	6.31e-01	-8.38e-02	8.85e-01
REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	12	6.33e-01	7.97e-02	8.86e-01
REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	10	6.34e-01	-8.71e-02	8.86e-01
REACTOME RAF ACTIVATION	33	6.34e-01	4.80e-02	8.86e-01
REACTOME ERK MAPK TARGETS	20	6.34e-01	6.15e-02	8.86e-01
REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	11	6.35e-01	-8.27e-02	8.87e-01
REACTOME ACTIVATION OF TRKA RECEPTORS	6	6.36e-01	1.12e-01	8.88e-01
REACTOME SYNDECAN INTERACTIONS	26	6.36e-01	-5.36e-02	8.88e-01
REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF	17	6.38e-01	6.60e-02	8.88e-01
REACTOME EPHB MEDIATED FORWARD SIGNALING	41	6.38e-01	-4.25e-02	8.88e-01
REACTOME SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS	43	6.38e-01	-4.14e-02	8.88e-01
REACTOME REGULATION OF LIPID METABOLISM BY PPARALPHA	115	6.40e-01	2.52e-02	8.88e-01
REACTOME ACYL CHAIN REMODELLING OF PE	29	6.40e-01	-5.02e-02	8.88e-01
REACTOME ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS	17	6.40e-01	-6.55e-02	8.88e-01
REACTOME INTERFERON GAMMA SIGNALING	88	6.40e-01	-2.88e-02	8.88e-01
REACTOME ACTIVATION OF NIMA KINASES NEK9 NEK6 NEK7	7	6.43e-01	-1.01e-01	8.90e-01
REACTOME SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL	25	6.44e-01	5.35e-02	8.90e-01
REACTOME TRIGLYCERIDE CATABOLISM	23	6.44e-01	5.57e-02	8.90e-01
REACTOME CELL CELL COMMUNICATION	126	6.44e-01	2.38e-02	8.90e-01
REACTOME INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	28	6.45e-01	5.03e-02	8.90e-01
REACTOME SARS COV 1 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS	16	6.45e-01	-6.66e-02	8.90e-01
REACTOME NOSTRIN MEDIATED ENOS TRAFFICKING	5	6.46e-01	1.19e-01	8.90e-01
REACTOME RHOBTB2 GTPASE CYCLE	22	6.47e-01	5.63e-02	8.92e-01
REACTOME SIGNALING BY MST1	5	6.50e-01	1.17e-01	8.94e-01
REACTOME ENOS ACTIVATION	11	6.51e-01	7.89e-02	8.94e-01
REACTOME VLDL CLEARANCE	6	6.51e-01	-1.07e-01	8.94e-01
REACTOME SIGNALING BY FGFR2 IIIA TM	19	6.54e-01	-5.95e-02	8.96e-01
REACTOME CD163 MEDIATING AN ANTI INFLAMMATORY RESPONSE	9	6.54e-01	-8.62e-02	8.96e-01
REACTOME BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA	6	6.55e-01	-1.05e-01	8.96e-01
REACTOME HS GAG BIOSYNTHESIS	28	6.55e-01	4.88e-02	8.96e-01
REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS	6	6.55e-01	1.05e-01	8.96e-01
REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS	55	6.55e-01	3.48e-02	8.96e-01
REACTOME IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS	17	6.56e-01	6.23e-02	8.96e-01
REACTOME SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS	74	6.57e-01	-2.99e-02	8.96e-01
REACTOME STIMULI SENSING CHANNELS	100	6.58e-01	2.56e-02	8.96e-01
REACTOME METAL ION SLC TRANSPORTERS	23	6.58e-01	-5.33e-02	8.96e-01
REACTOME EICOSANOID LIGAND BINDING RECEPTORS	14	6.59e-01	-6.81e-02	8.96e-01
REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS	29	6.59e-01	4.73e-02	8.96e-01
REACTOME DOPAMINE RECEPTORS	5	6.60e-01	1.14e-01	8.96e-01
REACTOME LYSINE CATABOLISM	12	6.62e-01	-7.30e-02	8.96e-01
REACTOME RHOD GTPASE CYCLE	49	6.62e-01	3.61e-02	8.96e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS	15	6.62e-01	6.51e-02	8.96e-01
REACTOME APOPTOTIC EXECUTION PHASE	49	6.63e-01	-3.60e-02	8.96e-01
REACTOME SYNTHESIS OF PI	5	6.64e-01	1.12e-01	8.96e-01
REACTOME PI METABOLISM	79	6.64e-01	2.82e-02	8.96e-01
REACTOME NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY	6	6.65e-01	1.02e-01	8.96e-01
REACTOME ACYL CHAIN REMODELLING OF PS	22	6.65e-01	-5.33e-02	8.96e-01
REACTOME EARLY SARS COV 2 INFECTION EVENTS	34	6.65e-01	-4.29e-02	8.96e-01
REACTOME TRIF MEDIATED PROGRAMMED CELL DEATH	9	6.66e-01	-8.30e-02	8.96e-01
REACTOME KILLING MECHANISMS	11	6.67e-01	7.50e-02	8.96e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES	43	6.67e-01	3.80e-02	8.96e-01
REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	18	6.67e-01	5.86e-02	8.96e-01
REACTOME FORMATION OF LATERAL PLATE MESODERM	5	6.68e-01	-1.11e-01	8.96e-01
REACTOME ACYL CHAIN REMODELING OF CL	5	6.68e-01	-1.11e-01	8.96e-01
REACTOME TRANSCRIPTIONAL REGULATION BY VENTX	41	6.68e-01	-3.87e-02	8.96e-01
REACTOME REGULATION OF RUNX1 EXPRESSION AND ACTIVITY	17	6.68e-01	-6.00e-02	8.96e-01
REACTOME DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE	17	6.71e-01	5.95e-02	8.98e-01
REACTOME NADE MODULATES DEATH SIGNALLING	5	6.72e-01	1.09e-01	8.99e-01
REACTOME NUCLEOTIDE BIOSYNTHESIS	14	6.74e-01	-6.50e-02	9.01e-01
REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	35	6.75e-01	-4.10e-02	9.01e-01
REACTOME SIGNALING BY NTRK2 TRKB	25	6.76e-01	-4.83e-02	9.01e-01
REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES	37	6.79e-01	3.93e-02	9.01e-01
REACTOME RET SIGNALING	40	6.79e-01	3.78e-02	9.01e-01
REACTOME VLDLR INTERNALISATION AND DEGRADATION	16	6.79e-01	-5.97e-02	9.01e-01
REACTOME PEXOPHAGY	11	6.80e-01	-7.19e-02	9.01e-01
REACTOME PROCESSING OF SMDT1	16	6.80e-01	-5.95e-02	9.01e-01
REACTOME DEFECTIVE CHST14 CAUSES EDS MUSCULOCONTRACTURAL TYPE	7	6.80e-01	8.99e-02	9.01e-01
REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	123	6.81e-01	2.14e-02	9.01e-01
REACTOME TELOMERE C STRAND LAGGING STRAND SYNTHESIS	33	6.82e-01	-4.13e-02	9.01e-01
REACTOME SYNTHESIS OF UDP N ACETYL GLUCOSAMINE	7	6.82e-01	8.95e-02	9.01e-01
REACTOME NETRIN MEDIATED REPULSION SIGNALS	8	6.82e-01	-8.37e-02	9.01e-01
REACTOME DEFECTIVE CHST6 CAUSES MCDC1	8	6.82e-01	8.35e-02	9.01e-01
REACTOME MHC CLASS II ANTIGEN PRESENTATION	121	6.82e-01	2.15e-02	9.01e-01
REACTOME EXTENSION OF TELOMERES	49	6.83e-01	-3.37e-02	9.01e-01
REACTOME SIGNALING BY WNT IN CANCER	32	6.84e-01	4.16e-02	9.01e-01
REACTOME BETA OXIDATION OF PRISTANOYL COA	9	6.84e-01	7.84e-02	9.01e-01
REACTOME MET ACTIVATES RAP1 AND RAC1	11	6.84e-01	-7.09e-02	9.01e-01
REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	160	6.85e-01	-1.86e-02	9.01e-01
REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	24	6.85e-01	4.78e-02	9.01e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES	15	6.86e-01	-6.02e-02	9.01e-01
REACTOME CREB PHOSPHORYLATION	6	6.87e-01	9.50e-02	9.01e-01
REACTOME ERYTHROPOIETIN ACTIVATES RAS	14	6.87e-01	-6.22e-02	9.01e-01
REACTOME RHO GTPASES ACTIVATE CIT	19	6.88e-01	5.33e-02	9.01e-01
REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE	5	6.88e-01	1.04e-01	9.01e-01
REACTOME RECEPTOR MEDIATED MITOPHAGY	10	6.89e-01	7.32e-02	9.01e-01
REACTOME RUNX3 REGULATES CDKN1A TRANSCRIPTION	7	6.89e-01	-8.74e-02	9.01e-01
REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	14	6.91e-01	-6.14e-02	9.02e-01
REACTOME INTERLEUKIN 1 PROCESSING	9	6.91e-01	-7.66e-02	9.02e-01
REACTOME STAT3 NUCLEAR EVENTS DOWNSTREAM OF ALK SIGNALING	9	6.92e-01	-7.64e-02	9.03e-01
REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS	27	6.93e-01	4.39e-02	9.04e-01
REACTOME CS DS DEGRADATION	12	6.95e-01	-6.54e-02	9.04e-01
REACTOME SYNTHESIS OF 12 EICOSATETRAENOIC ACID DERIVATIVES	7	6.95e-01	8.55e-02	9.04e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES	8	6.96e-01	7.99e-02	9.04e-01
REACTOME PHASE 1 INACTIVATION OF FAST NA CHANNELS	6	6.96e-01	9.22e-02	9.04e-01
REACTOME PROLACTIN RECEPTOR SIGNALING	15	6.96e-01	5.83e-02	9.04e-01
REACTOME RAC2 GTPASE CYCLE	81	6.97e-01	2.50e-02	9.05e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE	5	6.98e-01	1.00e-01	9.05e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH RAS	8	6.99e-01	-7.88e-02	9.06e-01
REACTOME REGULATION OF PTEN GENE TRANSCRIPTION	59	7.00e-01	2.90e-02	9.06e-01
REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	17	7.01e-01	-5.38e-02	9.06e-01
REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	20	7.01e-01	4.96e-02	9.06e-01
REACTOME METHIONINE SALVAGE PATHWAY	6	7.01e-01	9.04e-02	9.06e-01
REACTOME SIGNALING BY FLT3 FUSION PROTEINS	19	7.03e-01	-5.06e-02	9.07e-01
REACTOME RRNA PROCESSING IN THE MITOCHONDRION	9	7.04e-01	7.32e-02	9.08e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST	14	7.05e-01	5.84e-02	9.08e-01
REACTOME PLASMA LIPOPROTEIN REMODELING	33	7.05e-01	-3.80e-02	9.08e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3	11	7.05e-01	-6.58e-02	9.08e-01
REACTOME LATE SARS COV 2 INFECTION EVENTS	67	7.09e-01	2.64e-02	9.10e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	25	7.09e-01	4.31e-02	9.10e-01
REACTOME EPH EPHRIN SIGNALING	90	7.10e-01	2.27e-02	9.10e-01
REACTOME TERMINAL PATHWAY OF COMPLEMENT	8	7.10e-01	7.59e-02	9.10e-01
REACTOME DEATH RECEPTOR SIGNALING	143	7.11e-01	1.80e-02	9.10e-01
REACTOME CHREBP ACTIVATES METABOLIC GENE EXPRESSION	8	7.11e-01	7.57e-02	9.10e-01
REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	30	7.12e-01	3.89e-02	9.11e-01
REACTOME SIGNALING BY FGFR	85	7.13e-01	2.30e-02	9.11e-01
REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	11	7.14e-01	-6.39e-02	9.11e-01
REACTOME PP2A MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS	6	7.15e-01	8.62e-02	9.11e-01
REACTOME OPSINS	7	7.15e-01	7.97e-02	9.11e-01
REACTOME TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS	52	7.15e-01	-2.93e-02	9.11e-01
REACTOME NEUROTRANSMITTER CLEARANCE	9	7.15e-01	7.03e-02	9.11e-01
REACTOME HUR ELAVL1 BINDS AND STABILIZES MRNA	8	7.18e-01	7.38e-02	9.13e-01
REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	54	7.18e-01	-2.84e-02	9.13e-01
REACTOME RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION	6	7.18e-01	-8.51e-02	9.13e-01
REACTOME RHOBTB GTPASE CYCLE	34	7.21e-01	3.54e-02	9.13e-01
REACTOME NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION	20	7.22e-01	-4.59e-02	9.13e-01
REACTOME FORMATION OF AXIAL MESODERM	14	7.23e-01	-5.48e-02	9.13e-01
REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION	20	7.23e-01	-4.59e-02	9.13e-01
REACTOME ERKS ARE INACTIVATED	13	7.23e-01	5.68e-02	9.13e-01
REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	15	7.23e-01	-5.29e-02	9.13e-01
REACTOME TRAF6 MEDIATED NF KB ACTIVATION	24	7.23e-01	-4.18e-02	9.13e-01
REACTOME GLUTAMATE AND GLUTAMINE METABOLISM	13	7.23e-01	-5.67e-02	9.13e-01
REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS	299	7.23e-01	1.19e-02	9.13e-01
REACTOME INTERLEUKIN RECEPTOR SHC SIGNALING	24	7.25e-01	4.14e-02	9.15e-01
REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING	12	7.27e-01	5.82e-02	9.16e-01
REACTOME DEFECTIVE RIPK1 MEDIATED REGULATED NECROSIS	7	7.28e-01	-7.60e-02	9.16e-01
REACTOME REGULATION OF TP53 EXPRESSION AND DEGRADATION	37	7.28e-01	-3.30e-02	9.17e-01
REACTOME CYTOSOLIC TRNA AMINOACYLATION	22	7.30e-01	-4.26e-02	9.17e-01
REACTOME RESOLUTION OF ABASIC SITES AP SITES	38	7.30e-01	3.23e-02	9.17e-01
REACTOME VESICLE MEDIATED TRANSPORT	642	7.33e-01	-7.88e-03	9.20e-01
REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	28	7.34e-01	3.71e-02	9.21e-01
REACTOME TIGHT JUNCTION INTERACTIONS	29	7.36e-01	-3.62e-02	9.22e-01
REACTOME CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY	12	7.37e-01	5.59e-02	9.23e-01
REACTOME CREATION OF C4 AND C2 ACTIVATORS	14	7.37e-01	-5.18e-02	9.23e-01
REACTOME DEPOLYMERISATION OF THE NUCLEAR LAMINA	14	7.40e-01	-5.12e-02	9.26e-01
REACTOME SIGNALING BY NODAL	20	7.42e-01	4.25e-02	9.27e-01
REACTOME COSTIMULATION BY THE CD28 FAMILY	64	7.42e-01	-2.38e-02	9.27e-01
REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	63	7.43e-01	-2.38e-02	9.27e-01
REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS	101	7.44e-01	-1.88e-02	9.27e-01
REACTOME INTERLEUKIN 9 SIGNALING	7	7.45e-01	-7.09e-02	9.27e-01
REACTOME BASIGIN INTERACTIONS	24	7.47e-01	-3.81e-02	9.27e-01
REACTOME TRYPTOPHAN CATABOLISM	14	7.47e-01	4.98e-02	9.27e-01
REACTOME NEGATIVE REGULATION OF MET ACTIVITY	20	7.47e-01	-4.17e-02	9.27e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K	12	7.48e-01	5.36e-02	9.27e-01
REACTOME ION HOMEOSTASIS	52	7.49e-01	2.56e-02	9.27e-01
REACTOME O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS	38	7.50e-01	2.99e-02	9.27e-01
REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	9	7.50e-01	6.12e-02	9.27e-01
REACTOME TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS	43	7.50e-01	-2.80e-02	9.27e-01
REACTOME BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA	5	7.51e-01	-8.20e-02	9.27e-01
REACTOME NEGATIVE REGULATION OF MAPK PATHWAY	41	7.51e-01	-2.87e-02	9.27e-01
REACTOME VITAMINS	6	7.52e-01	-7.46e-02	9.27e-01
REACTOME ACTIVATION OF RAS IN B CELLS	5	7.52e-01	-8.18e-02	9.27e-01
REACTOME CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2	11	7.52e-01	-5.50e-02	9.27e-01
REACTOME NRCAM INTERACTIONS	6	7.52e-01	7.44e-02	9.27e-01
REACTOME INTRA GOLGI TRAFFIC	43	7.53e-01	2.77e-02	9.27e-01
REACTOME LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS	19	7.54e-01	-4.16e-02	9.27e-01
REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING	30	7.54e-01	3.31e-02	9.27e-01
REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	19	7.56e-01	-4.12e-02	9.28e-01
REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS	63	7.56e-01	2.26e-02	9.28e-01
REACTOME CA2 ACTIVATED K CHANNELS	9	7.57e-01	-5.96e-02	9.28e-01
REACTOME SUMO IS CONJUGATED TO E1 UBA2 SAE1	5	7.57e-01	-7.99e-02	9.28e-01
REACTOME CHYLOMICRON REMODELING	10	7.59e-01	5.60e-02	9.29e-01
REACTOME BIOSYNTHESIS OF MARESINS	8	7.60e-01	6.24e-02	9.29e-01
REACTOME PROCESSING AND ACTIVATION OF SUMO	10	7.60e-01	-5.57e-02	9.29e-01
REACTOME REGULATION OF SIGNALING BY NODAL	9	7.61e-01	-5.86e-02	9.29e-01
REACTOME HEME DEGRADATION	15	7.61e-01	-4.54e-02	9.29e-01
REACTOME SYNAPTIC ADHESION LIKE MOLECULES	19	7.62e-01	4.02e-02	9.29e-01
REACTOME CYP2E1 REACTIONS	10	7.62e-01	5.52e-02	9.29e-01
REACTOME SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION	8	7.63e-01	6.16e-02	9.29e-01
REACTOME SIGNALING BY PDGF	57	7.63e-01	2.31e-02	9.29e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES	11	7.63e-01	-5.25e-02	9.29e-01
REACTOME ION TRANSPORT BY P TYPE ATPASES	51	7.64e-01	2.43e-02	9.29e-01
REACTOME MET RECEPTOR RECYCLING	10	7.64e-01	-5.48e-02	9.29e-01
REACTOME REGULATION OF PTEN MRNA TRANSLATION	9	7.65e-01	5.76e-02	9.29e-01
REACTOME PHASE 0 RAPID DEPOLARISATION	31	7.69e-01	3.05e-02	9.31e-01
REACTOME SIGNALING BY RECEPTOR TYROSINE KINASES	507	7.69e-01	-7.63e-03	9.31e-01
REACTOME WNT MEDIATED ACTIVATION OF DVL	8	7.69e-01	-6.00e-02	9.31e-01
REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	51	7.69e-01	2.37e-02	9.31e-01
REACTOME DEFECTS IN BIOTIN BTN METABOLISM	8	7.70e-01	-5.98e-02	9.31e-01
REACTOME POLB DEPENDENT LONG PATCH BASE EXCISION REPAIR	8	7.70e-01	-5.97e-02	9.31e-01
REACTOME RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY	14	7.72e-01	-4.48e-02	9.32e-01
REACTOME COHESIN LOADING ONTO CHROMATIN	8	7.73e-01	-5.90e-02	9.32e-01
REACTOME NUCLEOTIDE SALVAGE	21	7.73e-01	-3.63e-02	9.32e-01
REACTOME MAPK1 ERK2 ACTIVATION	9	7.74e-01	5.54e-02	9.32e-01
REACTOME DISEASES OF MITOTIC CELL CYCLE	37	7.74e-01	-2.72e-02	9.32e-01
REACTOME DARPP 32 EVENTS	24	7.74e-01	-3.38e-02	9.32e-01
REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	57	7.75e-01	2.19e-02	9.32e-01
REACTOME TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS	55	7.76e-01	2.22e-02	9.32e-01
REACTOME RHO GTPASES ACTIVATE ROCKS	19	7.76e-01	3.77e-02	9.32e-01
REACTOME DEFECTS IN VITAMIN AND COFACTOR METABOLISM	21	7.76e-01	-3.58e-02	9.32e-01
REACTOME INSULIN PROCESSING	24	7.77e-01	3.34e-02	9.32e-01
REACTOME LDL CLEARANCE	19	7.78e-01	-3.74e-02	9.32e-01
REACTOME RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS	5	7.80e-01	7.22e-02	9.34e-01
REACTOME COBALAMIN CBL METABOLISM	7	7.80e-01	-6.10e-02	9.34e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING	5	7.82e-01	-7.16e-02	9.34e-01
REACTOME LIPOPHAGY	9	7.83e-01	-5.31e-02	9.34e-01
REACTOME METABOLISM OF STEROID HORMONES	35	7.83e-01	2.69e-02	9.34e-01
REACTOME SARS COV 2 MODULATES AUTOPHAGY	11	7.83e-01	-4.79e-02	9.34e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE	20	7.84e-01	-3.53e-02	9.34e-01
REACTOME DISORDERS OF TRANSMEMBRANE TRANSPORTERS	170	7.86e-01	-1.21e-02	9.34e-01
REACTOME INDUCTION OF CELL CELL FUSION	12	7.86e-01	4.52e-02	9.34e-01
REACTOME SYNTHESIS OF DOLICHYL PHOSPHATE	6	7.87e-01	6.37e-02	9.34e-01
REACTOME SIGNAL AMPLIFICATION	33	7.87e-01	-2.71e-02	9.34e-01
REACTOME HYDROLYSIS OF LPC	9	7.87e-01	5.19e-02	9.34e-01
REACTOME MET PROMOTES CELL MOTILITY	41	7.88e-01	2.43e-02	9.34e-01
REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES	34	7.88e-01	2.67e-02	9.34e-01
REACTOME IRE1ALPHA ACTIVATES CHAPERONES	48	7.89e-01	2.23e-02	9.34e-01
REACTOME ORGANIC CATION TRANSPORT	10	7.90e-01	4.86e-02	9.34e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS	11	7.91e-01	4.62e-02	9.34e-01
REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	29	7.91e-01	-2.85e-02	9.34e-01
REACTOME CTLA4 INHIBITORY SIGNALING	21	7.91e-01	3.34e-02	9.34e-01
REACTOME SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER	54	7.91e-01	-2.09e-02	9.34e-01
REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	10	7.93e-01	-4.80e-02	9.34e-01
REACTOME CHOLINE CATABOLISM	6	7.93e-01	6.19e-02	9.34e-01
REACTOME NEGATIVE REGULATION OF ACTIVITY OF TFAP2 AP 2 FAMILY TRANSCRIPTION FACTORS	10	7.96e-01	4.73e-02	9.34e-01
REACTOME SIGNALING BY MET	78	7.96e-01	1.69e-02	9.34e-01
REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM	50	7.96e-01	2.11e-02	9.34e-01
REACTOME MITOTIC TELOPHASE CYTOKINESIS	11	7.96e-01	-4.50e-02	9.34e-01
REACTOME PHOSPHORYLATION OF THE APC C	20	7.97e-01	-3.33e-02	9.34e-01
REACTOME NEUTROPHIL DEGRANULATION	460	7.97e-01	7.01e-03	9.34e-01
REACTOME DSCAM INTERACTIONS	11	7.97e-01	4.48e-02	9.34e-01
REACTOME RHOF GTPASE CYCLE	40	7.97e-01	-2.35e-02	9.34e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES	16	7.97e-01	-3.71e-02	9.34e-01
REACTOME CA2 PATHWAY	62	7.98e-01	-1.88e-02	9.34e-01
REACTOME MASTL FACILITATES MITOTIC PROGRESSION	10	7.99e-01	-4.64e-02	9.34e-01
REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	11	8.00e-01	4.42e-02	9.34e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY DVL INTERACTING PROTEINS	5	8.00e-01	6.56e-02	9.34e-01
REACTOME NEUROTRANSMITTER RELEASE CYCLE	48	8.00e-01	-2.11e-02	9.34e-01
REACTOME DIGESTION	17	8.03e-01	3.50e-02	9.37e-01
REACTOME PREGNENOLONE BIOSYNTHESIS	12	8.03e-01	4.15e-02	9.37e-01
REACTOME RAS SIGNALING DOWNSTREAM OF NF1 LOSS OF FUNCTION VARIANTS	7	8.04e-01	5.41e-02	9.37e-01
REACTOME ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS	5	8.05e-01	-6.39e-02	9.37e-01
REACTOME TELOMERE EXTENSION BY TELOMERASE	22	8.06e-01	-3.03e-02	9.37e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12	22	8.06e-01	-3.02e-02	9.37e-01
REACTOME ROLE OF ABL IN ROBO SLIT SIGNALING	8	8.06e-01	-5.00e-02	9.37e-01
REACTOME BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS	10	8.06e-01	4.47e-02	9.37e-01
REACTOME SIGNALING BY PDGFR IN DISEASE	20	8.08e-01	-3.13e-02	9.37e-01
REACTOME LIPID PARTICLE ORGANIZATION	6	8.08e-01	-5.71e-02	9.37e-01
REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL	41	8.09e-01	-2.18e-02	9.37e-01
REACTOME SCAVENGING BY CLASS B RECEPTORS	6	8.10e-01	5.68e-02	9.38e-01
REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE	19	8.10e-01	-3.18e-02	9.38e-01
REACTOME CD28 CO STIMULATION	32	8.14e-01	2.41e-02	9.41e-01
REACTOME PLATELET SENSITIZATION BY LDL	17	8.14e-01	-3.29e-02	9.41e-01
REACTOME ENDOSOMAL VACUOLAR PATHWAY	11	8.15e-01	-4.07e-02	9.41e-01
REACTOME METABOLISM OF AMINE DERIVED HORMONES	17	8.16e-01	3.25e-02	9.42e-01
REACTOME TRANSCRIPTIONAL REGULATION BY MECP2	60	8.17e-01	1.73e-02	9.42e-01
REACTOME L1CAM INTERACTIONS	112	8.19e-01	1.25e-02	9.44e-01
REACTOME LONG TERM POTENTIATION	22	8.20e-01	-2.80e-02	9.44e-01
REACTOME RHO GTPASES ACTIVATE KTN1	11	8.20e-01	-3.96e-02	9.44e-01
REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES	34	8.21e-01	-2.24e-02	9.44e-01
REACTOME ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS	11	8.22e-01	-3.92e-02	9.44e-01
REACTOME LEISHMANIA INFECTION	156	8.23e-01	1.04e-02	9.44e-01
REACTOME GOLGI TO ER RETROGRADE TRANSPORT	132	8.23e-01	1.13e-02	9.45e-01
REACTOME FOXO MEDIATED TRANSCRIPTION	65	8.25e-01	-1.59e-02	9.46e-01
REACTOME IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN	5	8.25e-01	5.70e-02	9.46e-01
REACTOME SIGNAL TRANSDUCTION BY L1	20	8.27e-01	-2.82e-02	9.46e-01
REACTOME RAF INDEPENDENT MAPK1 3 ACTIVATION	22	8.28e-01	-2.67e-02	9.46e-01
REACTOME BETA CATENIN PHOSPHORYLATION CASCADE	16	8.28e-01	3.13e-02	9.46e-01
REACTOME CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION	11	8.30e-01	3.75e-02	9.46e-01
REACTOME POST TRANSCRIPTIONAL SILENCING BY SMALL RNAS	7	8.30e-01	4.69e-02	9.46e-01
REACTOME FORMATION OF XYLULOSE 5 PHOSPHATE	5	8.30e-01	-5.54e-02	9.46e-01
REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	21	8.30e-01	2.70e-02	9.46e-01
REACTOME SEROTONIN NEUROTRANSMITTER RELEASE CYCLE	17	8.31e-01	2.99e-02	9.46e-01
REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS	19	8.32e-01	-2.82e-02	9.46e-01
REACTOME GLUTATHIONE CONJUGATION	33	8.32e-01	-2.14e-02	9.46e-01
REACTOME ACYL CHAIN REMODELLING OF PC	27	8.33e-01	2.35e-02	9.47e-01
REACTOME ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS	20	8.33e-01	2.72e-02	9.47e-01
REACTOME COMPLEMENT CASCADE	54	8.34e-01	-1.65e-02	9.47e-01
REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS	17	8.35e-01	2.92e-02	9.47e-01
REACTOME SARS COV 2 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS	12	8.36e-01	3.44e-02	9.48e-01
REACTOME PURINE CATABOLISM	17	8.37e-01	-2.87e-02	9.48e-01
REACTOME ACTIVATION OF BH3 ONLY PROTEINS	30	8.38e-01	-2.16e-02	9.48e-01
REACTOME ESTROGEN BIOSYNTHESIS	6	8.38e-01	-4.82e-02	9.48e-01
REACTOME METABOLISM OF FAT SOLUBLE VITAMINS	46	8.40e-01	-1.72e-02	9.49e-01
REACTOME CGMP EFFECTS	16	8.40e-01	2.92e-02	9.49e-01
REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX	32	8.41e-01	2.05e-02	9.50e-01
REACTOME ABACAVIR ADME	9	8.41e-01	3.85e-02	9.50e-01
REACTOME CIPROFLOXACIN ADME	5	8.42e-01	-5.14e-02	9.50e-01
REACTOME CHYLOMICRON ASSEMBLY	10	8.46e-01	-3.54e-02	9.53e-01
REACTOME GAP JUNCTION DEGRADATION	12	8.47e-01	3.22e-02	9.53e-01
REACTOME ER QUALITY CONTROL COMPARTMENT ERQC	21	8.47e-01	-2.42e-02	9.53e-01
REACTOME KINESINS	59	8.48e-01	1.45e-02	9.53e-01
REACTOME DEFECTIVE EXT2 CAUSES EXOSTOSES 2	12	8.48e-01	3.20e-02	9.53e-01
REACTOME PHENYLALANINE METABOLISM	6	8.51e-01	4.42e-02	9.56e-01
REACTOME SIGNALING BY LEPTIN	11	8.52e-01	3.26e-02	9.56e-01
REACTOME HIV ELONGATION ARREST AND RECOVERY	33	8.52e-01	1.87e-02	9.56e-01
REACTOME UNWINDING OF DNA	12	8.54e-01	-3.07e-02	9.57e-01
REACTOME INTERLEUKIN 2 FAMILY SIGNALING	40	8.55e-01	1.67e-02	9.57e-01
REACTOME TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS	82	8.56e-01	1.16e-02	9.57e-01
REACTOME REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION	84	8.57e-01	-1.14e-02	9.57e-01
REACTOME CROSS PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS PHAGOSOMES	6	8.58e-01	-4.23e-02	9.57e-01
REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	14	8.58e-01	-2.77e-02	9.57e-01
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	55	8.58e-01	1.40e-02	9.57e-01
REACTOME GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION	14	8.59e-01	2.74e-02	9.58e-01
REACTOME RUNX3 REGULATES BCL2L11 BIM TRANSCRIPTION	5	8.60e-01	4.56e-02	9.58e-01
REACTOME N GLYCAN TRIMMING AND ELONGATION IN THE CIS GOLGI	5	8.61e-01	-4.53e-02	9.58e-01
REACTOME PYRIMIDINE CATABOLISM	12	8.61e-01	-2.92e-02	9.58e-01
REACTOME GLYCOSPHINGOLIPID METABOLISM	39	8.62e-01	1.61e-02	9.59e-01
REACTOME TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS	29	8.63e-01	1.85e-02	9.59e-01
REACTOME COPI MEDIATED ANTEROGRADE TRANSPORT	101	8.63e-01	-9.91e-03	9.59e-01
REACTOME TRANSCRIPTIONAL REGULATION BY E2F6	32	8.63e-01	1.76e-02	9.59e-01
REACTOME SIGNALING BY FGFR4	40	8.65e-01	1.56e-02	9.59e-01
REACTOME FANCONI ANEMIA PATHWAY	35	8.65e-01	1.66e-02	9.59e-01
REACTOME LYSOSPHINGOLIPID AND LPA RECEPTORS	14	8.66e-01	-2.61e-02	9.59e-01
REACTOME METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES	33	8.66e-01	-1.70e-02	9.59e-01
REACTOME INTERLEUKIN 6 SIGNALING	11	8.66e-01	-2.93e-02	9.59e-01
REACTOME DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS	19	8.67e-01	2.21e-02	9.59e-01
REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS	83	8.67e-01	-1.06e-02	9.59e-01
REACTOME MITOCHONDRIAL CALCIUM ION TRANSPORT	23	8.69e-01	-1.98e-02	9.60e-01
REACTOME SUMOYLATION OF RNA BINDING PROTEINS	47	8.70e-01	1.38e-02	9.60e-01
REACTOME POTENTIAL THERAPEUTICS FOR SARS	92	8.73e-01	-9.61e-03	9.63e-01
REACTOME ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS	41	8.75e-01	1.42e-02	9.65e-01
REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	111	8.77e-01	8.50e-03	9.65e-01
REACTOME SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL	8	8.77e-01	3.15e-02	9.65e-01
REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION	10	8.79e-01	2.78e-02	9.66e-01
REACTOME METABOLISM OF VITAMINS AND COFACTORS	185	8.79e-01	-6.49e-03	9.66e-01
REACTOME MINERALOCORTICOID BIOSYNTHESIS	6	8.80e-01	3.56e-02	9.66e-01
REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	20	8.82e-01	-1.92e-02	9.66e-01
REACTOME DEFECTIVE CHSY1 CAUSES TPBS	7	8.82e-01	3.24e-02	9.66e-01
REACTOME PHOSPHORYLATION OF EMI1	6	8.83e-01	3.46e-02	9.66e-01
REACTOME TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS	26	8.84e-01	-1.66e-02	9.66e-01
REACTOME INTRAFLAGELLAR TRANSPORT	50	8.85e-01	-1.18e-02	9.66e-01
REACTOME DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1	9	8.85e-01	2.78e-02	9.66e-01
REACTOME NGF INDEPENDANT TRKA ACTIVATION	5	8.86e-01	3.71e-02	9.66e-01
REACTOME PURINE SALVAGE	12	8.86e-01	2.40e-02	9.66e-01
REACTOME DECTIN 2 FAMILY	26	8.88e-01	1.59e-02	9.66e-01
REACTOME INTERLEUKIN 6 FAMILY SIGNALING	24	8.91e-01	-1.62e-02	9.66e-01
REACTOME TRAIL SIGNALING	8	8.91e-01	-2.80e-02	9.66e-01
REACTOME INTEGRIN CELL SURFACE INTERACTIONS	83	8.92e-01	8.61e-03	9.66e-01
REACTOME NFE2L2 REGULATING ANTI OXIDANT DETOXIFICATION ENZYMES	17	8.92e-01	1.90e-02	9.66e-01
REACTOME SIGNALLING TO ERKS	34	8.93e-01	-1.33e-02	9.66e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1	25	8.93e-01	1.55e-02	9.66e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH PI3K	6	8.93e-01	3.16e-02	9.66e-01
REACTOME G2 M DNA REPLICATION CHECKPOINT	5	8.93e-01	-3.46e-02	9.66e-01
REACTOME GLYCOGEN METABOLISM	22	8.93e-01	1.65e-02	9.66e-01
REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4	33	8.93e-01	-1.35e-02	9.66e-01
REACTOME INTERLEUKIN 35 SIGNALLING	12	8.94e-01	2.22e-02	9.66e-01
REACTOME RAC3 GTPASE CYCLE	85	8.94e-01	-8.36e-03	9.66e-01
REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	183	8.95e-01	5.67e-03	9.66e-01
REACTOME G1 S SPECIFIC TRANSCRIPTION	28	8.95e-01	-1.44e-02	9.66e-01
REACTOME DEFECTS IN COBALAMIN B12 METABOLISM	13	8.95e-01	-2.11e-02	9.66e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	14	8.96e-01	-2.03e-02	9.66e-01
REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY	5	8.96e-01	3.38e-02	9.66e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD4	15	8.97e-01	1.94e-02	9.66e-01
REACTOME RHO GTPASES ACTIVATE IQGAPS	31	8.98e-01	1.33e-02	9.66e-01
REACTOME MEMBRANE TRAFFICKING	603	8.99e-01	-3.03e-03	9.66e-01
REACTOME SENSORY PROCESSING OF SOUND	72	8.99e-01	-8.63e-03	9.66e-01
REACTOME UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION	19	9.01e-01	-1.65e-02	9.66e-01
REACTOME MELANIN BIOSYNTHESIS	5	9.01e-01	3.20e-02	9.66e-01
REACTOME ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION	28	9.02e-01	1.35e-02	9.66e-01
REACTOME DEFECTIVE B4GALT1 CAUSES B4GALT1 CDG CDG 2D	8	9.02e-01	2.51e-02	9.66e-01
REACTOME PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS	21	9.03e-01	1.54e-02	9.66e-01
REACTOME FBXW7 MUTANTS AND NOTCH1 IN CANCER	5	9.03e-01	-3.15e-02	9.66e-01
REACTOME SUMO IS TRANSFERRED FROM E1 TO E2 UBE2I UBC9	7	9.03e-01	-2.66e-02	9.66e-01
REACTOME SIGNALLING TO RAS	20	9.04e-01	1.56e-02	9.66e-01
REACTOME GLUCONEOGENESIS	33	9.04e-01	-1.21e-02	9.66e-01
REACTOME FATTY ACID METABOLISM	170	9.04e-01	-5.36e-03	9.66e-01
REACTOME HEMOSTASIS	591	9.04e-01	-2.90e-03	9.66e-01
REACTOME MUSCARINIC ACETYLCHOLINE RECEPTORS	5	9.04e-01	3.10e-02	9.66e-01
REACTOME ONCOGENIC MAPK SIGNALING	79	9.05e-01	7.76e-03	9.66e-01
REACTOME EPITHELIAL MESENCHYMAL TRANSITION EMT DURING GASTRULATION	7	9.05e-01	2.60e-02	9.66e-01
REACTOME REGULATION OF NPAS4 MRNA TRANSLATION	9	9.06e-01	-2.26e-02	9.67e-01
REACTOME BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA	5	9.09e-01	-2.94e-02	9.69e-01
REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	31	9.10e-01	-1.17e-02	9.69e-01
REACTOME SIGNALING BY FGFR2	72	9.12e-01	-7.57e-03	9.70e-01
REACTOME SUMOYLATION OF IMMUNE RESPONSE PROTEINS	10	9.13e-01	2.00e-02	9.71e-01
REACTOME SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS	14	9.15e-01	1.65e-02	9.72e-01
REACTOME VLDL ASSEMBLY	5	9.16e-01	-2.72e-02	9.73e-01
REACTOME MET RECEPTOR ACTIVATION	6	9.17e-01	-2.45e-02	9.73e-01
REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	35	9.18e-01	1.01e-02	9.73e-01
REACTOME TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE	20	9.20e-01	1.30e-02	9.75e-01
REACTOME SEMAPHORIN INTERACTIONS	61	9.21e-01	7.36e-03	9.75e-01
REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION	11	9.24e-01	1.67e-02	9.77e-01
REACTOME REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR	11	9.24e-01	1.67e-02	9.77e-01
REACTOME TYSND1 CLEAVES PEROXISOMAL PROTEINS	7	9.24e-01	-2.08e-02	9.77e-01
REACTOME DEADENYLATION OF MRNA	25	9.25e-01	-1.09e-02	9.77e-01
REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	30	9.27e-01	9.63e-03	9.79e-01
REACTOME NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	24	9.28e-01	-1.06e-02	9.79e-01
REACTOME BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA	5	9.29e-01	-2.31e-02	9.79e-01
REACTOME METABOLISM OF NUCLEOTIDES	94	9.30e-01	5.25e-03	9.79e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES	29	9.30e-01	9.42e-03	9.79e-01
REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS	81	9.30e-01	5.64e-03	9.79e-01
REACTOME RND1 GTPASE CYCLE	41	9.32e-01	7.72e-03	9.80e-01
REACTOME DEFECTIVE CHST3 CAUSES SEDCJD	7	9.32e-01	-1.86e-02	9.80e-01
REACTOME MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS	7	9.34e-01	-1.82e-02	9.81e-01
REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	11	9.35e-01	1.43e-02	9.81e-01
REACTOME PYROPTOSIS	27	9.35e-01	-9.06e-03	9.81e-01
REACTOME ENDOGENOUS STEROLS	26	9.35e-01	9.19e-03	9.81e-01
REACTOME MET ACTIVATES PTK2 SIGNALING	30	9.37e-01	-8.34e-03	9.82e-01
REACTOME NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	19	9.38e-01	1.03e-02	9.82e-01
REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	13	9.39e-01	1.22e-02	9.83e-01
REACTOME LYSOSOME VESICLE BIOGENESIS	33	9.40e-01	7.58e-03	9.83e-01
REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	11	9.42e-01	1.26e-02	9.85e-01
REACTOME UPTAKE AND FUNCTION OF ANTHRAX TOXINS	11	9.44e-01	1.23e-02	9.85e-01
REACTOME ERYTHROPOIETIN ACTIVATES STAT5	7	9.44e-01	-1.53e-02	9.85e-01
REACTOME SIGNALING BY NOTCH1	69	9.44e-01	-4.86e-03	9.85e-01
REACTOME TRP CHANNELS	27	9.45e-01	7.69e-03	9.85e-01
REACTOME RIP MEDIATED NFKB ACTIVATION VIA ZBP1	16	9.47e-01	9.66e-03	9.86e-01
REACTOME MTOR SIGNALLING	40	9.48e-01	-5.92e-03	9.87e-01
REACTOME RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES	16	9.50e-01	8.99e-03	9.88e-01
REACTOME PLASMA LIPOPROTEIN CLEARANCE	37	9.51e-01	5.80e-03	9.88e-01
REACTOME BIOTIN TRANSPORT AND METABOLISM	10	9.51e-01	1.11e-02	9.88e-01
REACTOME MISCELLANEOUS TRANSPORT AND BINDING EVENTS	24	9.51e-01	7.18e-03	9.88e-01
REACTOME SUMO IS PROTEOLYTICALLY PROCESSED	6	9.52e-01	-1.42e-02	9.88e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	14	9.54e-01	8.96e-03	9.89e-01
REACTOME SIGNALING BY RETINOIC ACID	41	9.54e-01	-5.15e-03	9.89e-01
REACTOME AMINO ACIDS REGULATE MTORC1	53	9.55e-01	-4.49e-03	9.89e-01
REACTOME PIWI INTERACTING RNA PIRNA BIOGENESIS	29	9.55e-01	6.05e-03	9.89e-01
REACTOME ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS	10	9.56e-01	-1.00e-02	9.89e-01
REACTOME MUCOPOLYSACCHARIDOSES	10	9.56e-01	9.98e-03	9.89e-01
REACTOME MITOCHONDRIAL UNCOUPLING	5	9.57e-01	1.38e-02	9.89e-01
REACTOME PI3K AKT SIGNALING IN CANCER	103	9.57e-01	3.04e-03	9.89e-01
REACTOME VASOPRESSIN LIKE RECEPTORS	5	9.58e-01	1.35e-02	9.89e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	36	9.60e-01	4.79e-03	9.89e-01
REACTOME PLATELET AGGREGATION PLUG FORMATION	39	9.60e-01	4.60e-03	9.89e-01
REACTOME OTHER SEMAPHORIN INTERACTIONS	18	9.60e-01	6.76e-03	9.89e-01
REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES	21	9.64e-01	5.70e-03	9.92e-01
REACTOME HYALURONAN METABOLISM	17	9.65e-01	6.22e-03	9.92e-01
REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES	29	9.65e-01	4.71e-03	9.92e-01
REACTOME METABOLISM OF FOLATE AND PTERINES	17	9.65e-01	6.13e-03	9.92e-01
REACTOME RAP1 SIGNALLING	16	9.67e-01	-5.93e-03	9.92e-01
REACTOME CELLULAR HEXOSE TRANSPORT	21	9.67e-01	-5.15e-03	9.92e-01
REACTOME PI5P REGULATES TP53 ACETYLATION	9	9.67e-01	7.85e-03	9.92e-01
REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	26	9.68e-01	4.59e-03	9.92e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING	5	9.68e-01	-1.02e-02	9.92e-01
REACTOME NEUREXINS AND NEUROLIGINS	51	9.69e-01	3.12e-03	9.92e-01
REACTOME POLO LIKE KINASE MEDIATED EVENTS	16	9.71e-01	-5.22e-03	9.94e-01
REACTOME AGGREPHAGY	42	9.73e-01	3.02e-03	9.95e-01
REACTOME SERINE BIOSYNTHESIS	9	9.74e-01	-6.29e-03	9.95e-01
REACTOME RIBAVIRIN ADME	11	9.75e-01	-5.47e-03	9.96e-01
REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	118	9.76e-01	1.63e-03	9.96e-01
REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	19	9.77e-01	-3.85e-03	9.96e-01
REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES	18	9.77e-01	3.89e-03	9.96e-01
REACTOME NEUROTOXICITY OF CLOSTRIDIUM TOXINS	10	9.80e-01	4.59e-03	9.98e-01
REACTOME SYNTHESIS OF LIPOXINS LX	6	9.82e-01	-5.45e-03	9.98e-01
REACTOME COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC	98	9.82e-01	-1.35e-03	9.98e-01
REACTOME RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR	19	9.83e-01	2.82e-03	9.98e-01
REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK	17	9.84e-01	-2.88e-03	9.98e-01
REACTOME RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA	7	9.84e-01	-4.27e-03	9.98e-01
REACTOME ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS	20	9.84e-01	-2.52e-03	9.98e-01
REACTOME INTERLEUKIN 27 SIGNALING	11	9.85e-01	3.26e-03	9.98e-01
REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	17	9.86e-01	-2.43e-03	9.98e-01
REACTOME P38MAPK EVENTS	13	9.86e-01	2.78e-03	9.98e-01
REACTOME ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN	13	9.86e-01	-2.71e-03	9.98e-01
REACTOME SYNTHESIS OF 15 EICOSATETRAENOIC ACID DERIVATIVES	6	9.87e-01	3.83e-03	9.98e-01
REACTOME AURKA ACTIVATION BY TPX2	69	9.88e-01	-1.09e-03	9.98e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE	74	9.88e-01	1.05e-03	9.98e-01
REACTOME PI3K AKT ACTIVATION	9	9.89e-01	-2.73e-03	9.98e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS	8	9.89e-01	-2.70e-03	9.98e-01
REACTOME SUPPRESSION OF APOPTOSIS	7	9.92e-01	-2.29e-03	9.98e-01
REACTOME SYNTHESIS OF 5 EICOSATETRAENOIC ACIDS	9	9.92e-01	2.00e-03	9.98e-01
REACTOME CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND	9	9.92e-01	1.96e-03	9.98e-01
REACTOME ACYL CHAIN REMODELLING OF PG	18	9.93e-01	1.16e-03	9.98e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS	5	9.94e-01	1.98e-03	9.98e-01
REACTOME THYROXINE BIOSYNTHESIS	10	9.94e-01	-1.35e-03	9.98e-01
REACTOME KERATAN SULFATE DEGRADATION	13	9.94e-01	1.13e-03	9.98e-01
REACTOME DISEASES OF CARBOHYDRATE METABOLISM	31	9.95e-01	-7.13e-04	9.98e-01
REACTOME G PROTEIN ACTIVATION	24	9.95e-01	-6.82e-04	9.98e-01
REACTOME SIGNALING BY HEDGEHOG	148	9.96e-01	-2.55e-04	9.98e-01
REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS	16	9.96e-01	-6.42e-04	9.98e-01
REACTOME ACTIVATION OF PPARGC1A PGC 1ALPHA BY PHOSPHORYLATION	10	9.97e-01	7.91e-04	9.98e-01
REACTOME HIV TRANSCRIPTION ELONGATION	42	9.97e-01	-3.86e-04	9.98e-01
REACTOME APOPTOTIC FACTOR MEDIATED RESPONSE	19	9.97e-01	4.50e-04	9.98e-01
REACTOME ASPARAGINE N LINKED GLYCOSYLATION	299	1.00e+00	-1.16e-05	1.00e+00

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Detailed Gene set reports

REACTOME_TRANSLATION

REACTOME_TRANSLATION

	1152
set	REACTOME_TRANSLATION
setSize	278
pANOVA	4.49e-21
s.dist	-0.328
p.adjustANOVA	7.37e-18

Top enriched genes

Top 20 genes

GeneID	Gene Rank
EIF3G	-10319
RPL39L	-10291
SPCS1	-10221
SSR2	-10153
RPL18	-10087
RPL23	-9997
RPL35A	-9988
RPL38	-9969
TUFM	-9885
MRPS11	-9876
RPL11	-9821
RPS6	-9806
EEF1G	-9803
MRPL17	-9794
AIMP1	-9776
RPS28	-9678
RPL27A	-9667
RPL34	-9611
RPL26	-9600
N6AMT1	-9597

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
EIF3G	-10319.0
RPL39L	-10291.0
SPCS1	-10221.0
SSR2	-10153.0
RPL18	-10087.0
RPL23	-9997.0
RPL35A	-9988.0
RPL38	-9969.0
TUFM	-9885.0
MRPS11	-9876.0
RPL11	-9821.0
RPS6	-9806.0
EEF1G	-9803.0
MRPL17	-9794.0
AIMP1	-9776.0
RPS28	-9678.0
RPL27A	-9667.0
RPL34	-9611.0
RPL26	-9600.0
N6AMT1	-9597.0
RPL28	-9548.0
RPS18	-9512.0
EEF1B2	-9504.0
RPS26	-9490.0
SEC11C	-9480.0
RPS16	-9467.0
RPL3	-9459.0
RPS14	-9401.0
MRPL4	-9305.0
SEC61B	-9301.0
EIF3F	-9276.0
RPL9	-9273.0
MRPS18A	-9260.0
MRPL51	-9233.0
MRPL53	-9185.0
MRPL37	-9150.0
MRPL13	-9145.0
RPL5	-9093.0
RPS10	-9091.0
RPS3A	-8975.0
MRPL32	-8923.0
MRPL2	-8848.0
RPS3	-8834.0
RPL13	-8701.0
RPLP1	-8700.0
RPL32	-8650.0
MRPL46	-8605.0
MTFMT	-8556.0
YARS2	-8538.0
MRPS31	-8507.0
RPSA	-8467.0
MRPL15	-8425.0
MRPL58	-8421.0
EIF3J	-8418.0
MRPS15	-8403.0
MRPS7	-8395.0
SEC11A	-8337.0
MRPL48	-8207.0
MRPL10	-8177.0
AIMP2	-8156.0
EIF2S1	-8073.0
MRPS16	-8029.0
MRPL21	-8010.0
MRPL18	-7989.0
MARS2	-7979.0
MRPL12	-7921.0
RPLP0	-7893.0
MRPL33	-7871.0
RPS9	-7845.0
RPL17	-7840.0
WARS1	-7812.0
RPS19	-7779.0
MTIF3	-7770.0
RPS2	-7738.0
MRPL55	-7722.0
RPL4	-7711.0
MRPL40	-7710.0
EIF2B1	-7695.0
RPL36	-7654.0
MRPL36	-7524.0
RPL41	-7424.0
RPS8	-7382.0
SRPRB	-7364.0
RPL15	-7360.0
EARS2	-7231.0
RPN1	-7172.0
RPS7	-7130.0
CHCHD1	-7089.0
RPL37A	-7049.0
RPS15A	-7015.0
RPS29	-6975.0
EIF3I	-6950.0
MRPS23	-6927.0
RPL7A	-6925.0
SRP14	-6917.0
MRPS33	-6892.0
MRPL39	-6867.0
RPL18A	-6838.0
MRPL54	-6824.0
MRPS17	-6822.0
RPL37	-6792.0
SRP9	-6783.0
MRPL41	-6677.0
TSFM	-6642.0
TRMT112	-6447.0
SEC61G	-6441.0
EIF2S2	-6392.0
RPL8	-6347.0
MRPL14	-6344.0
RPS13	-6339.0
EIF3L	-6206.0
RPN2	-6204.0
RPS27L	-6200.0
SRP54	-6106.0
RPL35	-6032.0
RPL23A	-6024.0
NARS2	-5926.0
RPL27	-5884.0
EEF1A1	-5856.0
RPS11	-5850.0
MRPS30	-5841.0
EIF4H	-5819.0
MRPL27	-5785.0
RPL29	-5778.0
MRPL30	-5623.0
EIF4E	-5369.0
RPL22L1	-5348.0
RPS27	-5318.0
EIF4A1	-5317.0
MRPL47	-5312.0
MRPL3	-5232.0
PARS2	-5196.0
MRPL52	-5167.0
RPL12	-5128.0
ERAL1	-5119.0
AURKAIP1	-5110.0
FAU	-5092.0
MRPL9	-5079.0
EIF4EBP1	-5052.0
MRPL34	-4978.0
SEC61A1	-4963.0
UBA52	-4934.0
MRPL49	-4933.0
MRPL24	-4927.0
MRPS24	-4891.0
ETF1	-4857.0
MRPL50	-4848.0
KARS1	-4640.0
RPL7	-4473.0
MRPS12	-4463.0
MTIF2	-4460.0
EIF2B2	-4346.0
LARS1	-4317.0
RPL26L1	-4159.0
EIF3B	-4157.0
RPL13A	-4097.5
GADD45GIP1	-4001.0
EIF4A2	-3743.0
WARS2	-3717.0
SRP19	-3500.0
SRP68	-3488.0
DARS2	-3468.0
IARS2	-3455.0
EIF3E	-3449.0
RPS5	-3417.0
TARS2	-3196.0
MRPS18B	-3165.0
EIF4B	-3079.0
RPL36AL	-2981.5
EIF2B3	-2971.0
EIF2B4	-2952.0
RPL14	-2908.0
MRPL11	-2897.0
RPS12	-2751.0
PPA1	-2738.0
RPS27A	-2707.0
SARS2	-2608.0
RPS21	-2596.0
AARS1	-2433.0
MRPS10	-2313.0
MRPS26	-2275.0
MRPL42	-2238.0
OXA1L	-2063.0
GFM2	-2013.0
MRPS18C	-1832.0
EIF5B	-1814.0
RPL10A	-1720.0
EIF3M	-1602.0
RPL24	-1557.0
MRPL57	-1219.0
DAP3	-1107.0
MRPS21	-1038.0
EIF3D	-955.0
MRPL20	-903.0
RPL30	-893.0
FARSA	-848.0
MRPL1	-656.0
DARS1	-615.0
EPRS1	-563.0
GARS1	-500.0
RPS24	-456.0
SPCS2	-431.0
RPL6	-400.0
MRPL35	-145.0
MRPL43	289.0
RPS15	320.0
DDOST	322.0
FARSB	512.0
EIF3K	546.0
RARS1	665.0
NARS1	757.0
MRPS5	771.0
RPS20	828.0
EIF2B5	1073.0
MRPL44	1296.0
IARS1	1372.0
SPCS3	1398.0
RARS2	1507.0
SRP72	1723.0
MRRF	1981.0
MRPS14	2184.0
RPL21	2253.0
AARS2	2415.0
VARS1	2490.0
MRPS9	2503.0
SRPRA	2535.0
PPA2	2665.0
PTCD3	2740.0
EIF5	2884.0
MRPL19	2954.0
MRPL28	3045.0
MRPS25	3101.0
EEF1E1	3139.0
YARS1	3178.0
GFM1	3305.0
EEF2	3343.0
MRPS35	3398.0
RPLP2	3532.0
EEF1A2	3587.0
RPL31	3600.0
TARS1	3617.0
TRAM1	3828.0
MRPS34	3844.0
LARS2	4002.0
FARS2	4031.0
EIF4G1	4214.0
MRPS27	4220.0
VARS2	4278.0
MRPS2	4740.0
RPL19	4741.0
RPS25	4809.0
MRPS28	5122.0
SSR1	5709.0
EIF3H	5737.0
RPL22	5772.0
HARS2	5843.0
MRPL16	5883.0
MRPS22	5940.0
MTRF1L	6007.0
SEC61A2	6051.0
EIF3A	6273.0
RPS23	6291.0
PABPC1	6426.0
MARS1	6440.0
CARS2	6451.0
CARS1	6686.0
HARS1	7013.0
MRPL22	7020.0
GSPT1	7518.0
APEH	7771.0
SSR3	8045.0
MRPL38	8501.0
MRPS6	8821.0
RPL3L	9915.0
EEF1D	9949.0
RPL10L	10108.0
MRPL23	10125.0
MRPL45	11070.0

---

REACTOME_METABOLISM_OF_RNA

REACTOME_METABOLISM_OF_RNA

	1313
set	REACTOME_METABOLISM_OF_RNA
setSize	675
pANOVA	3.88e-19
s.dist	-0.202
p.adjustANOVA	3.18e-16

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ZFP36	-10684
ZCRB1	-10430
RPL39L	-10291
RBM8A	-10237
POLR2J	-10179
CDC5L	-10151
PCF11	-10113
RPL18	-10087
SEH1L	-10060
PNO1	-10056
GAR1	-10039
METTL3	-10033
RPL23	-9997
RPL35A	-9988
RPL38	-9969
HSPA8	-9899
SRSF10	-9852
POLR2I	-9848
APOBEC3C	-9843
RPL11	-9821

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ZFP36	-10684.0
ZCRB1	-10430.0
RPL39L	-10291.0
RBM8A	-10237.0
POLR2J	-10179.0
CDC5L	-10151.0
PCF11	-10113.0
RPL18	-10087.0
SEH1L	-10060.0
PNO1	-10056.0
GAR1	-10039.0
METTL3	-10033.0
RPL23	-9997.0
RPL35A	-9988.0
RPL38	-9969.0
HSPA8	-9899.0
SRSF10	-9852.0
POLR2I	-9848.0
APOBEC3C	-9843.0
RPL11	-9821.0
NUDT21	-9812.0
RPS6	-9806.0
FAM32A	-9738.0
RPS28	-9678.0
RPL27A	-9667.0
TRMT5	-9652.0
RPL34	-9611.0
RPL26	-9600.0
HNRNPA1	-9569.0
ISY1	-9568.0
SNRNP25	-9549.0
RPL28	-9548.0
XPOT	-9542.0
PSMD13	-9525.0
RPS18	-9512.0
SAP18	-9497.0
UTP4	-9491.0
RPS26	-9490.0
APOBEC3H	-9470.0
RPS16	-9467.0
WBP11	-9463.0
PAPOLA	-9460.0
RPL3	-9459.0
NIP7	-9449.0
EXOSC4	-9447.0
SNRNP35	-9443.0
HSPA1A	-9425.0
RNMT	-9412.0
RPS14	-9401.0
SNRPD2	-9397.0
HNRNPA3	-9386.0
A1CF	-9344.0
PRPF38A	-9327.0
NOL11	-9295.0
GEMIN5	-9279.0
PSMB8	-9275.0
NUP42	-9274.0
RPL9	-9273.0
EXOSC8	-9261.0
NUP43	-9181.0
LTV1	-9160.0
SRSF1	-9112.0
RPL5	-9093.0
RPS10	-9091.0
PSMA7	-9081.0
WDR12	-9062.0
PAIP1	-9028.0
RPS3A	-8975.0
TRMT6	-8950.0
MPHOSPH10	-8949.0
PPP2CA	-8916.0
KRR1	-8902.0
RNPC3	-8901.0
IGF2BP1	-8885.0
PCBP1	-8864.0
SRSF11	-8835.0
RPS3	-8834.0
U2SURP	-8815.0
RPL13	-8701.0
RPLP1	-8700.0
PSMA3	-8660.0
RPL32	-8650.0
WDR36	-8647.0
NUP107	-8608.0
FTSJ3	-8603.0
YBX1	-8570.0
SNW1	-8558.0
PRMT5	-8518.0
GEMIN2	-8513.0
NSRP1	-8509.0
DDX20	-8485.0
RPSA	-8467.0
PSMC5	-8460.0
YWHAZ	-8450.0
THOC1	-8436.0
ISG20L2	-8382.0
CPSF2	-8363.0
TRMT11	-8351.0
SNRPA	-8349.0
PSMD4	-8253.0
SDE2	-8240.0
WTAP	-8159.0
MAPKAPK2	-8129.0
DDX39A	-8097.0
UTP3	-8096.0
TRMT1	-8087.0
SNRNP48	-8067.0
THOC3	-8050.0
DCPS	-8042.0
UBC	-8040.0
SNU13	-8031.0
CWC15	-8013.0
SENP3	-7988.0
LUC7L3	-7956.0
NUP37	-7953.0
RTCB	-7933.0
METTL14	-7932.0
GTPBP3	-7927.0
TGS1	-7901.0
RPLP0	-7893.0
RPS9	-7845.0
RPL17	-7840.0
IGF2BP2	-7839.0
RIOK3	-7837.0
RPS19	-7779.0
MTO1	-7755.0
RPS2	-7738.0
WDR77	-7737.0
RPL4	-7711.0
IGF2BP3	-7707.0
PSMB2	-7696.0
NUP160	-7693.0
RPL36	-7654.0
CLNS1A	-7638.0
DIS3	-7622.0
SARNP	-7620.5
TRMT13	-7613.0
EXOSC9	-7610.0
HNRNPF	-7581.0
WDR3	-7553.0
SRSF3	-7539.0
POLR2E	-7485.0
TRMT10C	-7430.0
TRMT12	-7427.0
RPL41	-7424.0
TRMT10A	-7417.0
RPS8	-7382.0
RPPH1	-7366.0
RPL15	-7360.0
EFTUD2	-7349.0
PSME2	-7342.0
NSUN6	-7285.0
DDX21	-7212.0
POP7	-7177.0
PSMB3	-7156.0
PSMA4	-7153.0
RPS7	-7130.0
HNRNPM	-7129.0
PSMD7	-7104.0
RPL37A	-7049.0
RBM22	-7035.0
LENG1	-7033.0
RPS15A	-7015.0
LSM6	-7013.0
BUD31	-7007.0
RPS29	-6975.0
RPL7A	-6925.0
SF3B5	-6915.0
IK	-6869.0
NOP58	-6845.0
RPL18A	-6838.0
UTP20	-6830.0
RPL37	-6792.0
NT5C3B	-6782.0
DDX52	-6740.0
PSMB9	-6737.0
ZC3H11A	-6721.0
ADAT2	-6720.0
PSMC4	-6700.0
DHX8	-6691.0
PHAX	-6647.0
HNRNPL	-6643.0
AQR	-6633.0
UBL5	-6620.0
RIOK2	-6609.0
HNRNPA2B1	-6608.0
SNRPG	-6599.0
CPSF6	-6579.0
NUP50	-6564.0
SNRPD1	-6546.0
RBM28	-6472.0
TRMT112	-6447.0
PSMA5	-6442.0
POP1	-6435.0
NOP2	-6415.0
RPL8	-6347.0
GTF2H3	-6340.0
RPS13	-6339.0
PSMD11	-6284.0
GLE1	-6241.0
RPS27L	-6200.0
RPP40	-6184.0
PRORP	-6165.0
SNRPD3	-6155.0
LSM1	-6054.0
THOC5	-6040.0
RPL35	-6032.0
EDC3	-6027.0
RPL23A	-6024.0
CNOT11	-6014.0
CSTF3	-5991.0
PES1	-5960.0
TYW1	-5930.0
TRMT61B	-5917.0
SF3B3	-5896.0
RPL27	-5884.0
FAM98B	-5878.0
EXOSC5	-5874.0
SNRNP27	-5867.0
PRPF40A	-5857.0
RPS11	-5850.0
RPP14	-5848.0
SMG9	-5836.0
XPO1	-5829.0
CDK7	-5825.0
ERI1	-5811.0
SMG1	-5782.0
RPL29	-5778.0
SLBP	-5730.0
PAN3	-5694.0
RPP30	-5680.0
THOC6	-5609.0
MTREX	-5589.0
PSME3	-5547.0
U2AF1L4	-5492.0
ZFP36L1	-5485.0
IMP4	-5402.0
SF3B4	-5373.0
EIF4E	-5369.0
RPL22L1	-5348.0
CNOT9	-5320.0
RPS27	-5318.0
EIF4A1	-5317.0
MNAT1	-5299.0
EXOSC7	-5281.0
GEMIN6	-5280.0
SNRPN	-5261.0
PPIL3	-5249.0
DCAF13	-5245.0
SET	-5132.0
TRIT1	-5130.0
RPL12	-5128.0
FAU	-5092.0
BYSL	-5075.0
LSM3	-5062.0
UBB	-5059.0
NUP153	-5033.0
UTP6	-5021.0
DDX46	-4997.0
THUMPD1	-4991.0
PRPF4	-4948.0
APOBEC1	-4942.0
UBA52	-4934.0
MFAP1	-4914.0
CCNH	-4866.0
ETF1	-4857.0
PSMB10	-4811.0
SNIP1	-4809.0
PWP2	-4798.0
EBNA1BP2	-4792.0
ZNF830	-4785.0
RAN	-4756.0
UTP11	-4720.0
KHSRP	-4714.0
C2orf49	-4713.0
PSMA6	-4676.0
SRSF5	-4675.0
POLR2C	-4652.0
DIMT1	-4541.0
TSEN34	-4523.0
LSM5	-4486.0
UPF2	-4474.0
RPL7	-4473.0
PSMD9	-4450.0
DDX5	-4382.0
TPRKB	-4237.0
THG1L	-4219.0
CWC22	-4196.0
RPL26L1	-4159.0
USP39	-4155.0
RPL13A	-4097.5
SNRPA1	-4090.0
PHF5A	-4072.0
PNRC2	-4037.0
RBM7	-3943.0
DDX6	-3897.0
CSTF2T	-3889.0
SMG6	-3885.0
NOP10	-3800.0
PSMD5	-3781.0
POLDIP3	-3769.0
CWC27	-3756.0
HNRNPD	-3747.0
EIF4A2	-3743.0
BUD23	-3741.0
POLR2F	-3657.0
SMG7	-3652.0
DDX49	-3571.0
TRNT1	-3518.0
PDCD11	-3494.0
PSMC2	-3476.0
PSMA2	-3445.0
NUP155	-3436.0
RPS5	-3417.0
LSM10	-3403.0
RPP38	-3394.0
DDX41	-3384.0
C9orf78	-3381.0
PSMD6	-3380.0
SRSF2	-3347.0
YJU2	-3304.0
PSMB4	-3285.0
MAGOHB	-3262.0
TRMT9B	-3259.0
DCP2	-3244.0
CWF19L2	-3221.0
ZMAT5	-3127.0
GTF2H5	-3090.0
PSMC3	-3081.0
EIF4B	-3079.0
PPIE	-3077.0
CWC25	-3009.0
SF3A1	-2995.0
RPL36AL	-2981.5
RBM25	-2917.0
SKIC3	-2913.0
RPL14	-2908.0
TPR	-2890.0
SMG8	-2884.0
WDR43	-2876.0
SNUPN	-2855.0
ZBTB8OS	-2838.0
DCP1A	-2752.0
RPS12	-2751.0
SMG5	-2746.0
ZNF473	-2744.0
POLR2H	-2710.0
RPS27A	-2707.0
XRN1	-2644.0
PTBP1	-2639.0
NOL9	-2622.0
UTP15	-2599.0
RPS21	-2596.0
SF3A3	-2560.0
SNRNP70	-2548.0
RBM42	-2524.0
RTRAF	-2518.0
EMG1	-2504.0
NUP85	-2443.0
SRSF8	-2167.0
CNOT8	-2122.0
TYW5	-2082.0
NOL12	-2030.0
HNRNPU	-2019.0
DHX35	-2006.0
WBP4	-1992.0
TRDMT1	-1944.0
PAN2	-1913.0
NUP98	-1888.0
PELP1	-1844.0
PPP1R8	-1842.0
RBM39	-1826.0
PLRG1	-1820.0
PSMB6	-1764.0
CPSF3	-1733.0
WDR33	-1722.0
RPL10A	-1720.0
DNAJC8	-1714.0
PRKCA	-1685.0
SNRNP40	-1675.0
DDX39B	-1629.0
POLR2G	-1573.0
RPL24	-1557.0
SMU1	-1536.0
SRSF9	-1510.0
SF3B1	-1499.0
NXT1	-1374.0
CPSF7	-1371.0
SYF2	-1342.0
SNRPF	-1314.0
UPF3A	-1262.0
APOBEC3B	-1255.0
WDR46	-1237.0
TRA2B	-1197.0
RBM17	-1151.0
CNOT2	-1100.0
PPIH	-1067.0
PSMC6	-1062.0
SNRPB2	-922.0
MAPK11	-896.0
RPL30	-893.0
WDR75	-882.0
SF3B2	-881.0
DDX1	-847.0
CCDC12	-844.0
NXF1	-751.0
PPP2R2A	-748.0
LSM4	-734.0
LSM11	-652.0
TFB1M	-625.0
POLR2K	-624.0
TXNL4A	-621.0
PABPN1	-616.0
DDX23	-601.0
MPHOSPH6	-565.0
EPRS1	-563.0
PATL1	-496.0
PRPF31	-470.0
RPS24	-456.0
WDR18	-415.0
TSR1	-401.0
RPL6	-400.0
PRKRIP1	-379.0
POLR2L	-372.0
TNKS1BP1	-311.0
NUP58	-237.0
NOL6	-193.0
BUD13	-181.0
RPP25	-90.0
PUS1	-60.0
SEM1	-38.0
PSMB1	-28.0
QTRT1	62.0
SEC13	66.0
PUS7	76.0
TNPO1	112.0
SLU7	114.0
LSM2	156.0
CDC40	172.0
TSEN15	196.0
PPIG	217.0
SRSF7	284.0
PSMA1	296.0
CNOT7	309.0
RPS15	320.0
CNOT4	324.0
IMP3	348.0
PNN	385.0
NUP35	446.0
LSM8	468.0
DDX42	528.0
CRNKL1	530.0
DHX15	644.0
TP53RK	648.0
NCL	719.0
DDX47	742.0
FBL	791.0
RIOK1	805.0
RPS20	828.0
CCAR1	909.0
SF3A2	917.0
PARN	927.0
HNRNPK	936.0
CHTOP	948.0
UTP25	951.0
NOP14	997.0
ALKBH8	1030.0
ERCC2	1041.0
APOBEC3A	1049.0
MRM3	1081.0
DUS2	1110.0
SMNDC1	1137.0
NCBP1	1140.0
FIP1L1	1178.0
PRCC	1204.0
TSEN54	1241.0
ACIN1	1244.0
DHX38	1248.0
NUP88	1334.0
NDC1	1422.0
PSMB7	1455.0
RRP1	1505.0
NUP214	1526.0
PSME4	1583.0
NSUN4	1611.0
PSMB5	1628.0
RRP7A	1645.0
PDCD7	1682.0
ADAT1	1683.0
OSGEP	1748.0
FYTTD1	1764.0
ANP32A	1767.0
CNOT10	1780.0
POM121C	1782.0
YWHAB	1794.0
RBM5	1838.0
EXOSC3	1939.0
CDKAL1	2036.0
GEMIN7	2106.0
GTF2H1	2125.0
TNFSF13	2164.0
CLP1	2178.0
ALYREF	2245.0
RPL21	2253.0
RNGTT	2283.0
NUP188	2308.0
ADAR	2422.0
RPP21	2423.0
FCF1	2447.0
CNOT6L	2515.0
HBS1L	2566.0
CTU1	2604.0
UPF1	2626.0
GCFC2	2667.0
SRRT	2712.0
NCBP2	2717.0
TCERG1	2768.0
CNOT6	2866.0
ADARB1	2881.0
NUP54	2991.0
SF1	3041.0
MAGOH	3043.0
C1D	3116.0
PRPF19	3222.0
NUP133	3395.0
NUP62	3527.0
RPLP2	3532.0
SNRPC	3554.0
SRSF6	3596.0
RPL31	3600.0
ZMAT2	3667.0
NOC4L	3672.0
UTP18	3711.0
SUGP1	3735.0
HNRNPC	3774.0
METTL1	3803.0
PCBP2	3870.0
PRPF3	3877.0
WDR70	3897.0
GTF2F1	3903.0
CNOT1	3915.0
PPIL1	3924.0
GTF2F2	3988.0
PPWD1	4075.0
PUS3	4087.0
CASC3	4135.0
LCMT2	4148.0
EIF4G1	4214.0
PSMD3	4235.0
PSMC1	4252.0
RAE1	4292.0
GPATCH1	4300.0
TUT7	4332.0
SMN1	4401.5
SMN2	4401.5
MRM2	4497.0
THOC7	4498.0
EXOSC1	4509.0
NUP93	4585.0
AAAS	4604.0
RNPS1	4625.0
HSPB1	4649.0
RPL19	4741.0
CSNK1D	4765.0
RPS25	4809.0
MAPK14	4829.0
FUS	4914.0
PRPF18	4952.0
PSMD1	5004.0
POP5	5095.0
ELAC2	5131.0
APOBEC4	5151.0
SRSF4	5167.0
POLR2D	5189.0
SRRM2	5217.0
NUP205	5228.0
PSMF1	5263.0
CSTF1	5309.0
MRM1	5325.0
MTERF4	5356.0
BMS1	5397.0
DCP1B	5398.0
BCAS2	5488.0
SRRM1	5510.0
HNRNPR	5524.0
RCL1	5564.0
TYW3	5605.0
DHX16	5615.0
POLR2B	5721.0
GTF2H4	5742.0
RRP9	5743.0
RRP36	5760.0
RPL22	5772.0
RANBP2	5895.0
SNRPB	5980.0
PRKCD	5998.0
EXOSC6	6019.0
PPIL4	6060.0
PRPF6	6065.0
SNRPE	6152.0
CHERP	6194.0
XRN2	6268.0
RPS23	6291.0
DHX9	6346.0
PABPC1	6426.0
DHX37	6460.0
CACTIN	6468.0
GNL3	6513.0
TFIP11	6515.0
TSEN2	6535.0
LSM7	6575.0
SNRNP200	6580.0
WDR4	6601.0
POP4	6608.0
HNRNPH1	6766.0
PSMD12	6808.0
POLR2A	7019.0
PSME1	7056.0
POM121	7060.0
SUPT5H	7080.0
EIF4A3	7144.0
TUT4	7262.0
CTNNBL1	7396.0
ADAT3	7408.0
EXOSC10	7462.0
XAB2	7472.0
GSPT1	7518.0
NHP2	7554.0
EXOSC2	7600.0
NOP56	7677.0
HEATR1	7729.0
PPIL2	7752.0
TEX10	7828.0
NSUN2	7922.0
AKT1	7961.0
PSMA8	8011.0
THADA	8063.0
CTU2	8100.0
SART1	8131.0
CPSF1	8200.0
TRMT61A	8209.0
PSMD14	8243.0
PRPF8	8244.0
CPSF4	8260.0
CNOT3	8263.0
GEMIN4	8340.0
QTRT2	8344.0
TSR3	8393.0
PUF60	8431.0
U2AF2	8519.0
SRSF12	8610.0
NOB1	8627.0
PPP2R1A	8649.0
SKIC8	8662.0
ERCC3	8718.0
TRMU	8838.0
BOP1	8867.0
CSNK1E	9055.0
ELAVL1	9056.0
SF3B6	9215.0
URM1	9299.0
SYMPK	9413.0
PSMD8	9422.0
NUP210	9431.0
NAT10	9713.0
SKIC2	9825.0
TBL3	9872.0
PSMD2	9891.0
RPL3L	9915.0
TRMT44	9975.0
RPL10L	10108.0
EDC4	10247.0
APOBEC2	10412.0
PSMB11	10612.0
UTP14C	10711.0

---

REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE

REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE

	271
set	REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE
setSize	105
pANOVA	7.75e-16
s.dist	-0.455
p.adjustANOVA	3.99e-13

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL39L	-10291
SPCS1	-10221
SSR2	-10153
RPL18	-10087
RPL23	-9997
RPL35A	-9988
RPL38	-9969
RPL11	-9821
RPS6	-9806
RPS28	-9678
RPL27A	-9667
RPL34	-9611
RPL26	-9600
RPL28	-9548
RPS18	-9512
RPS26	-9490
SEC11C	-9480
RPS16	-9467
RPL3	-9459
RPS14	-9401

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL39L	-10291.0
SPCS1	-10221.0
SSR2	-10153.0
RPL18	-10087.0
RPL23	-9997.0
RPL35A	-9988.0
RPL38	-9969.0
RPL11	-9821.0
RPS6	-9806.0
RPS28	-9678.0
RPL27A	-9667.0
RPL34	-9611.0
RPL26	-9600.0
RPL28	-9548.0
RPS18	-9512.0
RPS26	-9490.0
SEC11C	-9480.0
RPS16	-9467.0
RPL3	-9459.0
RPS14	-9401.0
SEC61B	-9301.0
RPL9	-9273.0
RPL5	-9093.0
RPS10	-9091.0
RPS3A	-8975.0
RPS3	-8834.0
RPL13	-8701.0
RPLP1	-8700.0
RPL32	-8650.0
RPSA	-8467.0
SEC11A	-8337.0
RPLP0	-7893.0
RPS9	-7845.0
RPL17	-7840.0
RPS19	-7779.0
RPS2	-7738.0
RPL4	-7711.0
RPL36	-7654.0
RPL41	-7424.0
RPS8	-7382.0
SRPRB	-7364.0
RPL15	-7360.0
RPN1	-7172.0
RPS7	-7130.0
RPL37A	-7049.0
RPS15A	-7015.0
RPS29	-6975.0
RPL7A	-6925.0
SRP14	-6917.0
RPL18A	-6838.0
RPL37	-6792.0
SRP9	-6783.0
SEC61G	-6441.0
RPL8	-6347.0
RPS13	-6339.0
RPN2	-6204.0
RPS27L	-6200.0
SRP54	-6106.0
RPL35	-6032.0
RPL23A	-6024.0
RPL27	-5884.0
RPS11	-5850.0
RPL29	-5778.0
RPL22L1	-5348.0
RPS27	-5318.0
RPL12	-5128.0
FAU	-5092.0
SEC61A1	-4963.0
UBA52	-4934.0
RPL7	-4473.0
RPL26L1	-4159.0
RPL13A	-4097.5
SRP19	-3500.0
SRP68	-3488.0
RPS5	-3417.0
RPL36AL	-2981.5
RPL14	-2908.0
RPS12	-2751.0
RPS27A	-2707.0
RPS21	-2596.0
RPL10A	-1720.0
RPL24	-1557.0
RPL30	-893.0
RPS24	-456.0
SPCS2	-431.0
RPL6	-400.0
RPS15	320.0
DDOST	322.0
RPS20	828.0
SPCS3	1398.0
SRP72	1723.0
RPL21	2253.0
SRPRA	2535.0
RPLP2	3532.0
RPL31	3600.0
TRAM1	3828.0
RPL19	4741.0
RPS25	4809.0
SSR1	5709.0
RPL22	5772.0
SEC61A2	6051.0
RPS23	6291.0
SSR3	8045.0
RPL3L	9915.0
RPL10L	10108.0

---

REACTOME_EUKARYOTIC_TRANSLATION_INITIATION

REACTOME_EUKARYOTIC_TRANSLATION_INITIATION

	1149
set	REACTOME_EUKARYOTIC_TRANSLATION_INITIATION
setSize	110
pANOVA	9.72e-16
s.dist	-0.443
p.adjustANOVA	3.99e-13

Top enriched genes

Top 20 genes

GeneID	Gene Rank
EIF3G	-10319
RPL39L	-10291
RPL18	-10087
RPL23	-9997
RPL35A	-9988
RPL38	-9969
RPL11	-9821
RPS6	-9806
RPS28	-9678
RPL27A	-9667
RPL34	-9611
RPL26	-9600
RPL28	-9548
RPS18	-9512
RPS26	-9490
RPS16	-9467
RPL3	-9459
RPS14	-9401
EIF3F	-9276
RPL9	-9273

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
EIF3G	-10319.0
RPL39L	-10291.0
RPL18	-10087.0
RPL23	-9997.0
RPL35A	-9988.0
RPL38	-9969.0
RPL11	-9821.0
RPS6	-9806.0
RPS28	-9678.0
RPL27A	-9667.0
RPL34	-9611.0
RPL26	-9600.0
RPL28	-9548.0
RPS18	-9512.0
RPS26	-9490.0
RPS16	-9467.0
RPL3	-9459.0
RPS14	-9401.0
EIF3F	-9276.0
RPL9	-9273.0
RPL5	-9093.0
RPS10	-9091.0
RPS3A	-8975.0
RPS3	-8834.0
RPL13	-8701.0
RPLP1	-8700.0
RPL32	-8650.0
RPSA	-8467.0
EIF3J	-8418.0
EIF2S1	-8073.0
RPLP0	-7893.0
RPS9	-7845.0
RPL17	-7840.0
RPS19	-7779.0
RPS2	-7738.0
RPL4	-7711.0
EIF2B1	-7695.0
RPL36	-7654.0
RPL41	-7424.0
RPS8	-7382.0
RPL15	-7360.0
RPS7	-7130.0
RPL37A	-7049.0
RPS15A	-7015.0
RPS29	-6975.0
EIF3I	-6950.0
RPL7A	-6925.0
RPL18A	-6838.0
RPL37	-6792.0
EIF2S2	-6392.0
RPL8	-6347.0
RPS13	-6339.0
EIF3L	-6206.0
RPS27L	-6200.0
RPL35	-6032.0
RPL23A	-6024.0
RPL27	-5884.0
RPS11	-5850.0
EIF4H	-5819.0
RPL29	-5778.0
EIF4E	-5369.0
RPL22L1	-5348.0
RPS27	-5318.0
EIF4A1	-5317.0
RPL12	-5128.0
FAU	-5092.0
EIF4EBP1	-5052.0
UBA52	-4934.0
RPL7	-4473.0
EIF2B2	-4346.0
RPL26L1	-4159.0
EIF3B	-4157.0
RPL13A	-4097.5
EIF4A2	-3743.0
EIF3E	-3449.0
RPS5	-3417.0
EIF4B	-3079.0
RPL36AL	-2981.5
EIF2B3	-2971.0
EIF2B4	-2952.0
RPL14	-2908.0
RPS12	-2751.0
RPS27A	-2707.0
RPS21	-2596.0
EIF5B	-1814.0
RPL10A	-1720.0
EIF3M	-1602.0
RPL24	-1557.0
EIF3D	-955.0
RPL30	-893.0
RPS24	-456.0
RPL6	-400.0
RPS15	320.0
EIF3K	546.0
RPS20	828.0
EIF2B5	1073.0
RPL21	2253.0
EIF5	2884.0
RPLP2	3532.0
RPL31	3600.0
EIF4G1	4214.0
RPL19	4741.0
RPS25	4809.0
EIF3H	5737.0
RPL22	5772.0
EIF3A	6273.0
RPS23	6291.0
PABPC1	6426.0
RPL3L	9915.0
RPL10L	10108.0

---

REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION

REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION

	151
set	REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION
setSize	87
pANOVA	2.36e-14
s.dist	-0.473
p.adjustANOVA	7.76e-12

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL39L	-10291
RPL18	-10087
RPL23	-9997
RPL35A	-9988
RPL38	-9969
RPL11	-9821
RPS6	-9806
EEF1G	-9803
RPS28	-9678
RPL27A	-9667
RPL34	-9611
RPL26	-9600
RPL28	-9548
RPS18	-9512
EEF1B2	-9504
RPS26	-9490
RPS16	-9467
RPL3	-9459
RPS14	-9401
RPL9	-9273

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL39L	-10291.0
RPL18	-10087.0
RPL23	-9997.0
RPL35A	-9988.0
RPL38	-9969.0
RPL11	-9821.0
RPS6	-9806.0
EEF1G	-9803.0
RPS28	-9678.0
RPL27A	-9667.0
RPL34	-9611.0
RPL26	-9600.0
RPL28	-9548.0
RPS18	-9512.0
EEF1B2	-9504.0
RPS26	-9490.0
RPS16	-9467.0
RPL3	-9459.0
RPS14	-9401.0
RPL9	-9273.0
RPL5	-9093.0
RPS10	-9091.0
RPS3A	-8975.0
RPS3	-8834.0
RPL13	-8701.0
RPLP1	-8700.0
RPL32	-8650.0
RPSA	-8467.0
RPLP0	-7893.0
RPS9	-7845.0
RPL17	-7840.0
RPS19	-7779.0
RPS2	-7738.0
RPL4	-7711.0
RPL36	-7654.0
RPL41	-7424.0
RPS8	-7382.0
RPL15	-7360.0
RPS7	-7130.0
RPL37A	-7049.0
RPS15A	-7015.0
RPS29	-6975.0
RPL7A	-6925.0
RPL18A	-6838.0
RPL37	-6792.0
RPL8	-6347.0
RPS13	-6339.0
RPS27L	-6200.0
RPL35	-6032.0
RPL23A	-6024.0
RPL27	-5884.0
EEF1A1	-5856.0
RPS11	-5850.0
RPL29	-5778.0
RPL22L1	-5348.0
RPS27	-5318.0
RPL12	-5128.0
FAU	-5092.0
UBA52	-4934.0
RPL7	-4473.0
RPL26L1	-4159.0
RPL13A	-4097.5
RPS5	-3417.0
RPL36AL	-2981.5
RPL14	-2908.0
RPS12	-2751.0
RPS27A	-2707.0
RPS21	-2596.0
RPL10A	-1720.0
RPL24	-1557.0
RPL30	-893.0
RPS24	-456.0
RPL6	-400.0
RPS15	320.0
RPS20	828.0
RPL21	2253.0
EEF2	3343.0
RPLP2	3532.0
EEF1A2	3587.0
RPL31	3600.0
RPL19	4741.0
RPS25	4809.0
RPL22	5772.0
RPS23	6291.0
RPL3L	9915.0
EEF1D	9949.0
RPL10L	10108.0

---

REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY

REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY

	1486
set	REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY
setSize	94
pANOVA	1.44e-13
s.dist	-0.441
p.adjustANOVA	3.93e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL39L	-10291
RPL18	-10087
RPL23	-9997
RPL35A	-9988
RPL38	-9969
RPL11	-9821
RPS6	-9806
RPS28	-9678
RPL27A	-9667
RPL34	-9611
RPL26	-9600
RPL28	-9548
RPS18	-9512
RPS26	-9490
RPS16	-9467
RPL3	-9459
RPS14	-9401
RPL9	-9273
RPL5	-9093
RPS10	-9091

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL39L	-10291.0
RPL18	-10087.0
RPL23	-9997.0
RPL35A	-9988.0
RPL38	-9969.0
RPL11	-9821.0
RPS6	-9806.0
RPS28	-9678.0
RPL27A	-9667.0
RPL34	-9611.0
RPL26	-9600.0
RPL28	-9548.0
RPS18	-9512.0
RPS26	-9490.0
RPS16	-9467.0
RPL3	-9459.0
RPS14	-9401.0
RPL9	-9273.0
RPL5	-9093.0
RPS10	-9091.0
RPS3A	-8975.0
RPS3	-8834.0
RPL13	-8701.0
RPLP1	-8700.0
RPL32	-8650.0
CEBPB	-8501.0
RPSA	-8467.0
EIF2S1	-8073.0
RPLP0	-7893.0
RPS9	-7845.0
RPL17	-7840.0
RPS19	-7779.0
RPS2	-7738.0
RPL4	-7711.0
RPL36	-7654.0
RPL41	-7424.0
RPS8	-7382.0
RPL15	-7360.0
DDIT3	-7249.0
RPS7	-7130.0
RPL37A	-7049.0
RPS15A	-7015.0
RPS29	-6975.0
RPL7A	-6925.0
RPL18A	-6838.0
RPL37	-6792.0
EIF2S2	-6392.0
RPL8	-6347.0
RPS13	-6339.0
RPS27L	-6200.0
RPL35	-6032.0
RPL23A	-6024.0
RPL27	-5884.0
RPS11	-5850.0
ATF2	-5831.0
RPL29	-5778.0
RPL22L1	-5348.0
RPS27	-5318.0
RPL12	-5128.0
FAU	-5092.0
UBA52	-4934.0
RPL7	-4473.0
RPL26L1	-4159.0
RPL13A	-4097.5
RPS5	-3417.0
CEBPG	-3078.0
RPL36AL	-2981.5
RPL14	-2908.0
RPS12	-2751.0
RPS27A	-2707.0
RPS21	-2596.0
ATF4	-1852.0
RPL10A	-1720.0
RPL24	-1557.0
RPL30	-893.0
RPS24	-456.0
RPL6	-400.0
RPS15	320.0
RPS20	828.0
RPL21	2253.0
ATF3	3315.0
RPLP2	3532.0
EIF2AK4	3594.0
RPL31	3600.0
TRIB3	3731.0
GCN1	4487.0
RPL19	4741.0
RPS25	4809.0
RPL22	5772.0
ASNS	5979.0
RPS23	6291.0
IMPACT	9568.0
RPL3L	9915.0
RPL10L	10108.0

---

REACTOME_INFLUENZA_INFECTION

REACTOME_INFLUENZA_INFECTION

	228
set	REACTOME_INFLUENZA_INFECTION
setSize	149
pANOVA	1.92e-13
s.dist	-0.349
p.adjustANOVA	4.5e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL39L	-10291
POLR2J	-10179
RPL18	-10087
SEH1L	-10060
RPL23	-9997
RPL35A	-9988
RPL38	-9969
POLR2I	-9848
RPL11	-9821
RPS6	-9806
RPS28	-9678
RPL27A	-9667
RPL34	-9611
RPL26	-9600
RPL28	-9548
RPS18	-9512
RPS26	-9490
RPS16	-9467
RPL3	-9459
HSPA1A	-9425

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL39L	-10291.0
POLR2J	-10179.0
RPL18	-10087.0
SEH1L	-10060.0
RPL23	-9997.0
RPL35A	-9988.0
RPL38	-9969.0
POLR2I	-9848.0
RPL11	-9821.0
RPS6	-9806.0
RPS28	-9678.0
RPL27A	-9667.0
RPL34	-9611.0
RPL26	-9600.0
RPL28	-9548.0
RPS18	-9512.0
RPS26	-9490.0
RPS16	-9467.0
RPL3	-9459.0
HSPA1A	-9425.0
RPS14	-9401.0
NUP42	-9274.0
RPL9	-9273.0
NUP43	-9181.0
RPL5	-9093.0
RPS10	-9091.0
RPS3A	-8975.0
RPS3	-8834.0
RPL13	-8701.0
RPLP1	-8700.0
RPL32	-8650.0
NUP107	-8608.0
RPSA	-8467.0
ISG15	-8165.0
NUP37	-7953.0
CLTA	-7950.0
RPLP0	-7893.0
RPS9	-7845.0
RPL17	-7840.0
KPNA4	-7797.0
RPS19	-7779.0
RPS2	-7738.0
RPL4	-7711.0
NUP160	-7693.0
RPL36	-7654.0
PARP1	-7536.0
CALR	-7509.0
POLR2E	-7485.0
KPNB1	-7455.0
RPL41	-7424.0
RPS8	-7382.0
RPL15	-7360.0
RPS7	-7130.0
RPL37A	-7049.0
RPS15A	-7015.0
RPS29	-6975.0
RPL7A	-6925.0
RPL18A	-6838.0
RPL37	-6792.0
TGFB1	-6722.0
NUP50	-6564.0
RPL8	-6347.0
RPS13	-6339.0
RPS27L	-6200.0
RPL35	-6032.0
RPL23A	-6024.0
RPL27	-5884.0
RPS11	-5850.0
XPO1	-5829.0
RPL29	-5778.0
CANX	-5651.0
HSP90AA1	-5595.0
KPNA1	-5353.0
RPL22L1	-5348.0
RPS27	-5318.0
RPL12	-5128.0
FAU	-5092.0
NUP153	-5033.0
UBA52	-4934.0
RAN	-4756.0
POLR2C	-4652.0
RPL7	-4473.0
RPL26L1	-4159.0
RPL13A	-4097.5
GRSF1	-4077.0
POLR2F	-3657.0
NUP155	-3436.0
RPS5	-3417.0
CLTC	-3396.0
RPL36AL	-2981.5
RPL14	-2908.0
TPR	-2890.0
RPS12	-2751.0
POLR2H	-2710.0
RPS27A	-2707.0
RPS21	-2596.0
KPNA5	-2456.0
NUP85	-2443.0
NUP98	-1888.0
RPL10A	-1720.0
POLR2G	-1573.0
RPL24	-1557.0
RPL30	-893.0
IPO5	-800.0
POLR2K	-624.0
PABPN1	-616.0
DNAJC3	-592.0
RPS24	-456.0
RPL6	-400.0
KPNA7	-385.0
POLR2L	-372.0
NUP58	-237.0
SEC13	66.0
RPS15	320.0
NUP35	446.0
RPS20	828.0
NUP88	1334.0
NDC1	1422.0
NUP214	1526.0
POM121C	1782.0
RPL21	2253.0
NUP188	2308.0
NUP54	2991.0
KPNA2	3004.0
EIF2AK2	3299.0
KPNA3	3312.0
NUP133	3395.0
NUP62	3527.0
RPLP2	3532.0
RPL31	3600.0
GTF2F1	3903.0
GTF2F2	3988.0
RAE1	4292.0
NUP93	4585.0
AAAS	4604.0
RPL19	4741.0
RPS25	4809.0
POLR2D	5189.0
NUP205	5228.0
POLR2B	5721.0
RPL22	5772.0
RANBP2	5895.0
RPS23	6291.0
POLR2A	7019.0
POM121	7060.0
CPSF4	8260.0
NUP210	9431.0
RPL3L	9915.0
RPL10L	10108.0

---

REACTOME_RRNA_PROCESSING

REACTOME_RRNA_PROCESSING

	1148
set	REACTOME_RRNA_PROCESSING
setSize	192
pANOVA	1.24e-12
s.dist	-0.297
p.adjustANOVA	2.54e-10

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL39L	-10291
RPL18	-10087
PNO1	-10056
GAR1	-10039
RPL23	-9997
RPL35A	-9988
RPL38	-9969
RPL11	-9821
RPS6	-9806
RPS28	-9678
RPL27A	-9667
RPL34	-9611
RPL26	-9600
RPL28	-9548
RPS18	-9512
UTP4	-9491
RPS26	-9490
RPS16	-9467
RPL3	-9459
NIP7	-9449

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL39L	-10291.0
RPL18	-10087.0
PNO1	-10056.0
GAR1	-10039.0
RPL23	-9997.0
RPL35A	-9988.0
RPL38	-9969.0
RPL11	-9821.0
RPS6	-9806.0
RPS28	-9678.0
RPL27A	-9667.0
RPL34	-9611.0
RPL26	-9600.0
RPL28	-9548.0
RPS18	-9512.0
UTP4	-9491.0
RPS26	-9490.0
RPS16	-9467.0
RPL3	-9459.0
NIP7	-9449.0
EXOSC4	-9447.0
RPS14	-9401.0
NOL11	-9295.0
RPL9	-9273.0
EXOSC8	-9261.0
LTV1	-9160.0
RPL5	-9093.0
RPS10	-9091.0
WDR12	-9062.0
RPS3A	-8975.0
MPHOSPH10	-8949.0
KRR1	-8902.0
RPS3	-8834.0
RPL13	-8701.0
RPLP1	-8700.0
RPL32	-8650.0
WDR36	-8647.0
FTSJ3	-8603.0
RPSA	-8467.0
ISG20L2	-8382.0
UTP3	-8096.0
SNU13	-8031.0
SENP3	-7988.0
RPLP0	-7893.0
RPS9	-7845.0
RPL17	-7840.0
RIOK3	-7837.0
RPS19	-7779.0
RPS2	-7738.0
RPL4	-7711.0
RPL36	-7654.0
DIS3	-7622.0
EXOSC9	-7610.0
WDR3	-7553.0
TRMT10C	-7430.0
RPL41	-7424.0
RPS8	-7382.0
RPL15	-7360.0
DDX21	-7212.0
RPS7	-7130.0
RPL37A	-7049.0
RPS15A	-7015.0
RPS29	-6975.0
RPL7A	-6925.0
NOP58	-6845.0
RPL18A	-6838.0
UTP20	-6830.0
RPL37	-6792.0
DDX52	-6740.0
RIOK2	-6609.0
RBM28	-6472.0
TRMT112	-6447.0
NOP2	-6415.0
RPL8	-6347.0
RPS13	-6339.0
RPS27L	-6200.0
RPP40	-6184.0
PRORP	-6165.0
RPL35	-6032.0
RPL23A	-6024.0
PES1	-5960.0
RPL27	-5884.0
EXOSC5	-5874.0
RPS11	-5850.0
RPP14	-5848.0
ERI1	-5811.0
RPL29	-5778.0
RPP30	-5680.0
MTREX	-5589.0
IMP4	-5402.0
RPL22L1	-5348.0
RPS27	-5318.0
EXOSC7	-5281.0
DCAF13	-5245.0
RPL12	-5128.0
FAU	-5092.0
BYSL	-5075.0
UTP6	-5021.0
THUMPD1	-4991.0
UBA52	-4934.0
PWP2	-4798.0
EBNA1BP2	-4792.0
UTP11	-4720.0
DIMT1	-4541.0
RPL7	-4473.0
RPL26L1	-4159.0
RPL13A	-4097.5
NOP10	-3800.0
BUD23	-3741.0
DDX49	-3571.0
PDCD11	-3494.0
RPS5	-3417.0
RPP38	-3394.0
RPL36AL	-2981.5
RPL14	-2908.0
WDR43	-2876.0
RPS12	-2751.0
RPS27A	-2707.0
NOL9	-2622.0
UTP15	-2599.0
RPS21	-2596.0
EMG1	-2504.0
NOL12	-2030.0
PELP1	-1844.0
RPL10A	-1720.0
RPL24	-1557.0
WDR46	-1237.0
RPL30	-893.0
WDR75	-882.0
TFB1M	-625.0
MPHOSPH6	-565.0
RPS24	-456.0
WDR18	-415.0
TSR1	-401.0
RPL6	-400.0
NOL6	-193.0
RPP25	-90.0
RPS15	320.0
IMP3	348.0
NCL	719.0
DDX47	742.0
FBL	791.0
RIOK1	805.0
RPS20	828.0
UTP25	951.0
NOP14	997.0
MRM3	1081.0
RRP1	1505.0
NSUN4	1611.0
RRP7A	1645.0
EXOSC3	1939.0
RPL21	2253.0
RPP21	2423.0
FCF1	2447.0
C1D	3116.0
RPLP2	3532.0
RPL31	3600.0
NOC4L	3672.0
UTP18	3711.0
MRM2	4497.0
EXOSC1	4509.0
RPL19	4741.0
CSNK1D	4765.0
RPS25	4809.0
ELAC2	5131.0
MRM1	5325.0
MTERF4	5356.0
BMS1	5397.0
RCL1	5564.0
RRP9	5743.0
RRP36	5760.0
RPL22	5772.0
EXOSC6	6019.0
XRN2	6268.0
RPS23	6291.0
DHX37	6460.0
GNL3	6513.0
EXOSC10	7462.0
NHP2	7554.0
EXOSC2	7600.0
NOP56	7677.0
HEATR1	7729.0
TEX10	7828.0
TSR3	8393.0
NOB1	8627.0
BOP1	8867.0
CSNK1E	9055.0
NAT10	9713.0
TBL3	9872.0
RPL3L	9915.0
RPL10L	10108.0
UTP14C	10711.0

---

REACTOME_NONSENSE_MEDIATED_DECAY_NMD

REACTOME_NONSENSE_MEDIATED_DECAY_NMD

	1443
set	REACTOME_NONSENSE_MEDIATED_DECAY_NMD
setSize	107
pANOVA	2.43e-12
s.dist	-0.392
p.adjustANOVA	4.43e-10

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL39L	-10291
RBM8A	-10237
RPL18	-10087
RPL23	-9997
RPL35A	-9988
RPL38	-9969
RPL11	-9821
RPS6	-9806
RPS28	-9678
RPL27A	-9667
RPL34	-9611
RPL26	-9600
RPL28	-9548
RPS18	-9512
RPS26	-9490
RPS16	-9467
RPL3	-9459
RPS14	-9401
RPL9	-9273
RPL5	-9093

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL39L	-10291.0
RBM8A	-10237.0
RPL18	-10087.0
RPL23	-9997.0
RPL35A	-9988.0
RPL38	-9969.0
RPL11	-9821.0
RPS6	-9806.0
RPS28	-9678.0
RPL27A	-9667.0
RPL34	-9611.0
RPL26	-9600.0
RPL28	-9548.0
RPS18	-9512.0
RPS26	-9490.0
RPS16	-9467.0
RPL3	-9459.0
RPS14	-9401.0
RPL9	-9273.0
RPL5	-9093.0
RPS10	-9091.0
RPS3A	-8975.0
PPP2CA	-8916.0
RPS3	-8834.0
RPL13	-8701.0
RPLP1	-8700.0
RPL32	-8650.0
RPSA	-8467.0
RPLP0	-7893.0
RPS9	-7845.0
RPL17	-7840.0
RPS19	-7779.0
RPS2	-7738.0
RPL4	-7711.0
RPL36	-7654.0
RPL41	-7424.0
RPS8	-7382.0
RPL15	-7360.0
RPS7	-7130.0
RPL37A	-7049.0
RPS15A	-7015.0
RPS29	-6975.0
RPL7A	-6925.0
RPL18A	-6838.0
RPL37	-6792.0
RPL8	-6347.0
RPS13	-6339.0
RPS27L	-6200.0
RPL35	-6032.0
RPL23A	-6024.0
RPL27	-5884.0
RPS11	-5850.0
SMG9	-5836.0
SMG1	-5782.0
RPL29	-5778.0
RPL22L1	-5348.0
RPS27	-5318.0
RPL12	-5128.0
FAU	-5092.0
UBA52	-4934.0
ETF1	-4857.0
UPF2	-4474.0
RPL7	-4473.0
RPL26L1	-4159.0
RPL13A	-4097.5
PNRC2	-4037.0
SMG6	-3885.0
SMG7	-3652.0
RPS5	-3417.0
MAGOHB	-3262.0
RPL36AL	-2981.5
RPL14	-2908.0
SMG8	-2884.0
DCP1A	-2752.0
RPS12	-2751.0
SMG5	-2746.0
RPS27A	-2707.0
RPS21	-2596.0
RPL10A	-1720.0
RPL24	-1557.0
UPF3A	-1262.0
RPL30	-893.0
PPP2R2A	-748.0
RPS24	-456.0
RPL6	-400.0
RPS15	320.0
RPS20	828.0
NCBP1	1140.0
RPL21	2253.0
UPF1	2626.0
NCBP2	2717.0
MAGOH	3043.0
RPLP2	3532.0
RPL31	3600.0
CASC3	4135.0
EIF4G1	4214.0
RNPS1	4625.0
RPL19	4741.0
RPS25	4809.0
RPL22	5772.0
RPS23	6291.0
PABPC1	6426.0
EIF4A3	7144.0
GSPT1	7518.0
PPP2R1A	8649.0
RPL3L	9915.0
RPL10L	10108.0

---

REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS

REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS

	1364
set	REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS
setSize	161
pANOVA	1.2e-10
s.dist	-0.294
p.adjustANOVA	1.97e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL39L	-10291
RBM8A	-10237
RPL18	-10087
RPL23	-9997
RPL35A	-9988
RPL38	-9969
RPL11	-9821
RPS6	-9806
RPS28	-9678
RPL27A	-9667
RPL34	-9611
RPL26	-9600
RPL28	-9548
PSMD13	-9525
RPS18	-9512
RPS26	-9490
RPS16	-9467
RPL3	-9459
RPS14	-9401
PSMB8	-9275

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL39L	-10291.0
RBM8A	-10237.0
RPL18	-10087.0
RPL23	-9997.0
RPL35A	-9988.0
RPL38	-9969.0
RPL11	-9821.0
RPS6	-9806.0
RPS28	-9678.0
RPL27A	-9667.0
RPL34	-9611.0
RPL26	-9600.0
RPL28	-9548.0
PSMD13	-9525.0
RPS18	-9512.0
RPS26	-9490.0
RPS16	-9467.0
RPL3	-9459.0
RPS14	-9401.0
PSMB8	-9275.0
RPL9	-9273.0
RPL5	-9093.0
RPS10	-9091.0
PSMA7	-9081.0
RPS3A	-8975.0
RPS3	-8834.0
RPL13	-8701.0
RPLP1	-8700.0
PSMA3	-8660.0
RPL32	-8650.0
RPSA	-8467.0
PSMC5	-8460.0
PSMD4	-8253.0
HOXA2	-8170.0
UBC	-8040.0
RPLP0	-7893.0
RPS9	-7845.0
RPL17	-7840.0
RPS19	-7779.0
RPS2	-7738.0
RPL4	-7711.0
PSMB2	-7696.0
RPL36	-7654.0
RPL41	-7424.0
RPS8	-7382.0
RPL15	-7360.0
PSME2	-7342.0
PSMB3	-7156.0
PSMA4	-7153.0
RPS7	-7130.0
PSMD7	-7104.0
RPL37A	-7049.0
RPS15A	-7015.0
RPS29	-6975.0
RPL7A	-6925.0
RPL18A	-6838.0
RPL37	-6792.0
PSMB9	-6737.0
PSMC4	-6700.0
PSMA5	-6442.0
RPL8	-6347.0
RPS13	-6339.0
PSMD11	-6284.0
RPS27L	-6200.0
RPL35	-6032.0
RPL23A	-6024.0
RPL27	-5884.0
RPS11	-5850.0
RPL29	-5778.0
PSME3	-5547.0
ROBO1	-5453.0
RPL22L1	-5348.0
RPS27	-5318.0
LDB1	-5289.0
RPL12	-5128.0
FAU	-5092.0
UBB	-5059.0
UBA52	-4934.0
ETF1	-4857.0
PSMB10	-4811.0
PSMA6	-4676.0
UPF2	-4474.0
RPL7	-4473.0
PSMD9	-4450.0
RPL26L1	-4159.0
RPL13A	-4097.5
PSMD5	-3781.0
PSMC2	-3476.0
PSMA2	-3445.0
RPS5	-3417.0
PSMD6	-3380.0
PSMB4	-3285.0
MAGOHB	-3262.0
RBX1	-3208.0
PSMC3	-3081.0
ISL1	-2988.0
RPL36AL	-2981.5
RPL14	-2908.0
RPS12	-2751.0
RPS27A	-2707.0
RPS21	-2596.0
LHX9	-2533.0
ROBO2	-2178.0
USP33	-2101.0
PSMB6	-1764.0
RPL10A	-1720.0
RPL24	-1557.0
MSI1	-1508.0
UPF3A	-1262.0
PSMC6	-1062.0
RPL30	-893.0
RPS24	-456.0
RPL6	-400.0
SEM1	-38.0
PSMB1	-28.0
PSMA1	296.0
RPS15	320.0
RPS20	828.0
NCBP1	1140.0
ROBO3	1249.0
PSMB7	1455.0
ELOC	1468.0
PSME4	1583.0
PSMB5	1628.0
SLIT2	1798.0
LHX2	1920.0
SLIT1	2136.0
LHX4	2151.0
RPL21	2253.0
NCBP2	2717.0
MAGOH	3043.0
RPLP2	3532.0
RPL31	3600.0
CASC3	4135.0
LHX3	4164.0
EIF4G1	4214.0
PSMD3	4235.0
PSMC1	4252.0
CUL2	4451.0
RNPS1	4625.0
RPL19	4741.0
RPS25	4809.0
PSMD1	5004.0
ELOB	5112.0
PSMF1	5263.0
RPL22	5772.0
RPS23	6291.0
PABPC1	6426.0
PSMD12	6808.0
PSME1	7056.0
EIF4A3	7144.0
GSPT1	7518.0
PSMA8	8011.0
PSMD14	8243.0
DAG1	8601.0
PSMD8	9422.0
ZSWIM8	9838.0
PSMD2	9891.0
RPL3L	9915.0
RPL10L	10108.0
PSMB11	10612.0

---

REACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION

REACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION

	852
set	REACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION
setSize	84
pANOVA	2.49e-10
s.dist	-0.399
p.adjustANOVA	3.7e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
POLR1E	-10495.0
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
TBP	-9553.0
H2AC4	-9538.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
ACTB	-8412.0
H4C5	-8410.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
POLR1E	-10495.0
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
TBP	-9553.0
H2AC4	-9538.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
ACTB	-8412.0
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0
POLR1H	-8215.0
H2BC10	-8128.0
H2AC8	-7580.0
POLR2E	-7485.0
H3C10	-7442.0
DDX21	-7212.0
TAF1D	-7196.0
H4C6	-7171.0
GSK3B	-6981.0
H2BC11	-6443.0
POLR1C	-6163.0
H3C8	-5893.0
POLR1G	-5845.0
H2AJ	-5812.0
KAT2B	-5664.0
H4C12	-5632.0
H4C2	-5172.0
H2BC15	-5136.0
H4C4	-4850.0
H3C1	-4828.0
SMARCA5	-4808.0
H2BC8	-4740.0
POLR1F	-4737.0
BAZ1B	-4618.0
H2AX	-4613.0
POLR1B	-4549.0
EP300	-4543.0
H4C9	-4394.0
H3C6	-4228.0
H2BC12	-3934.0
POLR2F	-3657.0
H2BC6	-3615.0
H2AC14	-3153.0
H2BC1	-3120.0
POLR2H	-2710.0
H4C16	-2435.0
H3C11	-2128.0
TAF1B	-1985.0
H2BC21	-1800.0
SF3B1	-1499.0
POLR1D	-1301.0
H3-3A	-1031.0
H3-3B	-813.0
POLR2K	-624.0
H2AC20	-444.0
POLR2L	-372.0
H4C1	-204.0
KAT2A	-148.0
MYO1C	544.0
H2BC4	586.0
H2BC26	1116.0
POLR1A	2501.0
ERCC6	3768.0
H2AC6	3867.0
DEK	3890.0
H2AZ2	4572.0
TAF1A	4620.0
H3C12	6531.0
MYBBP1A	6607.0
H3C2	7476.0
TAF1C	8532.0
H4C13	8916.0

---

REACTOME_SELENOAMINO_ACID_METABOLISM

REACTOME_SELENOAMINO_ACID_METABOLISM

	484
set	REACTOME_SELENOAMINO_ACID_METABOLISM
setSize	108
pANOVA	2.71e-10
s.dist	-0.352
p.adjustANOVA	3.7e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL39L	-10291
MAT1A	-10220
RPL18	-10087
RPL23	-9997
RPL35A	-9988
RPL38	-9969
RPL11	-9821
RPS6	-9806
AIMP1	-9776
RPS28	-9678
RPL27A	-9667
RPL34	-9611
RPL26	-9600
RPL28	-9548
RPS18	-9512
RPS26	-9490
RPS16	-9467
RPL3	-9459
RPS14	-9401
RPL9	-9273

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL39L	-10291.0
MAT1A	-10220.0
RPL18	-10087.0
RPL23	-9997.0
RPL35A	-9988.0
RPL38	-9969.0
RPL11	-9821.0
RPS6	-9806.0
AIMP1	-9776.0
RPS28	-9678.0
RPL27A	-9667.0
RPL34	-9611.0
RPL26	-9600.0
RPL28	-9548.0
RPS18	-9512.0
RPS26	-9490.0
RPS16	-9467.0
RPL3	-9459.0
RPS14	-9401.0
RPL9	-9273.0
RPL5	-9093.0
RPS10	-9091.0
RPS3A	-8975.0
RPS3	-8834.0
RPL13	-8701.0
RPLP1	-8700.0
RPL32	-8650.0
RPSA	-8467.0
AIMP2	-8156.0
RPLP0	-7893.0
RPS9	-7845.0
RPL17	-7840.0
RPS19	-7779.0
RPS2	-7738.0
RPL4	-7711.0
RPL36	-7654.0
RPL41	-7424.0
RPS8	-7382.0
RPL15	-7360.0
RPS7	-7130.0
RPL37A	-7049.0
RPS15A	-7015.0
RPS29	-6975.0
RPL7A	-6925.0
RPL18A	-6838.0
RPL37	-6792.0
RPL8	-6347.0
RPS13	-6339.0
RPS27L	-6200.0
RPL35	-6032.0
RPL23A	-6024.0
RPL27	-5884.0
RPS11	-5850.0
RPL29	-5778.0
RPL22L1	-5348.0
RPS27	-5318.0
RPL12	-5128.0
FAU	-5092.0
UBA52	-4934.0
KARS1	-4640.0
RPL7	-4473.0
LARS1	-4317.0
RPL26L1	-4159.0
RPL13A	-4097.5
PSTK	-3525.0
RPS5	-3417.0
RPL36AL	-2981.5
RPL14	-2908.0
TXNRD1	-2861.0
RPS12	-2751.0
RPS27A	-2707.0
RPS21	-2596.0
SEPSECS	-1796.0
RPL10A	-1720.0
RPL24	-1557.0
CTH	-1195.0
SEPHS2	-1156.0
RPL30	-893.0
DARS1	-615.0
EPRS1	-563.0
RPS24	-456.0
RPL6	-400.0
RPS15	320.0
RARS1	665.0
RPS20	828.0
AHCY	1257.0
IARS1	1372.0
RPL21	2253.0
NNMT	3115.0
EEF1E1	3139.0
GNMT	3418.0
RPLP2	3532.0
PAPSS1	3586.0
RPL31	3600.0
RPL19	4741.0
RPS25	4809.0
PAPSS2	5293.0
RPL22	5772.0
RPS23	6291.0
MARS1	6440.0
INMT	6694.0
GSR	7348.0
SECISBP2	7412.0
SCLY	8755.0
RPL3L	9915.0
RPL10L	10108.0
EEFSEC	10313.0
HNMT	10511.0

---

REACTOME_RNA_POLYMERASE_I_PROMOTER_ESCAPE

REACTOME_RNA_POLYMERASE_I_PROMOTER_ESCAPE

	1157
set	REACTOME_RNA_POLYMERASE_I_PROMOTER_ESCAPE
setSize	83
pANOVA	2.53e-09
s.dist	-0.378
p.adjustANOVA	3.11e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
POLR1E	-10495.0
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
TBP	-9553.0
H2AC4	-9538.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
H4C5	-8410.0
H3C4	-8401.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
POLR1E	-10495.0
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
TBP	-9553.0
H2AC4	-9538.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0
POLR1H	-8215.0
H2BC10	-8128.0
H2AC8	-7580.0
POLR2E	-7485.0
H3C10	-7442.0
TAF1D	-7196.0
H4C6	-7171.0
H2BC11	-6443.0
GTF2H3	-6340.0
POLR1C	-6163.0
H3C8	-5893.0
POLR1G	-5845.0
CDK7	-5825.0
H2AJ	-5812.0
H4C12	-5632.0
MNAT1	-5299.0
H4C2	-5172.0
H2BC15	-5136.0
CCNH	-4866.0
H4C4	-4850.0
H3C1	-4828.0
H2BC8	-4740.0
POLR1F	-4737.0
H2AX	-4613.0
POLR1B	-4549.0
H4C9	-4394.0
H3C6	-4228.0
H2BC12	-3934.0
POLR2F	-3657.0
H2BC6	-3615.0
UBTF	-3295.0
H2AC14	-3153.0
H2BC1	-3120.0
GTF2H5	-3090.0
POLR2H	-2710.0
CBX3	-2592.0
H4C16	-2435.0
H3C11	-2128.0
TAF1B	-1985.0
H2BC21	-1800.0
POLR1D	-1301.0
H3-3A	-1031.0
H3-3B	-813.0
POLR2K	-624.0
H2AC20	-444.0
POLR2L	-372.0
H4C1	-204.0
H2BC4	586.0
ERCC2	1041.0
H2BC26	1116.0
GTF2H1	2125.0
POLR1A	2501.0
H2AC6	3867.0
H2AZ2	4572.0
TAF1A	4620.0
GTF2H4	5742.0
H3C12	6531.0
H3C2	7476.0
RRN3	7841.0
TAF1C	8532.0
ERCC3	8718.0
H4C13	8916.0

---

REACTOME_CELLULAR_RESPONSE_TO_STARVATION

REACTOME_CELLULAR_RESPONSE_TO_STARVATION

	1582
set	REACTOME_CELLULAR_RESPONSE_TO_STARVATION
setSize	147
pANOVA	2.65e-09
s.dist	-0.284
p.adjustANOVA	3.11e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL39L	-10291
CASTOR1	-10229
RPL18	-10087
SEH1L	-10060
ATP6V0E2	-10055
RPL23	-9997
RPL35A	-9988
RPL38	-9969
RPL11	-9821
RPS6	-9806
RPS28	-9678
RPL27A	-9667
RPL34	-9611
RPL26	-9600
RPL28	-9548
RPS18	-9512
RPS26	-9490
RPS16	-9467
RPL3	-9459
RPS14	-9401

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL39L	-10291.0
CASTOR1	-10229.0
RPL18	-10087.0
SEH1L	-10060.0
ATP6V0E2	-10055.0
RPL23	-9997.0
RPL35A	-9988.0
RPL38	-9969.0
RPL11	-9821.0
RPS6	-9806.0
RPS28	-9678.0
RPL27A	-9667.0
RPL34	-9611.0
RPL26	-9600.0
RPL28	-9548.0
RPS18	-9512.0
RPS26	-9490.0
RPS16	-9467.0
RPL3	-9459.0
RPS14	-9401.0
RPL9	-9273.0
RPL5	-9093.0
RPS10	-9091.0
RPS3A	-8975.0
RPS3	-8834.0
RPL13	-8701.0
RPLP1	-8700.0
RPL32	-8650.0
CEBPB	-8501.0
RPSA	-8467.0
EIF2S1	-8073.0
RPLP0	-7893.0
RPS9	-7845.0
RPL17	-7840.0
RPS19	-7779.0
RPS2	-7738.0
RPL4	-7711.0
RPL36	-7654.0
KICS2	-7633.0
RRAGC	-7551.0
RPL41	-7424.0
RPS8	-7382.0
RPL15	-7360.0
DDIT3	-7249.0
RHEB	-7173.0
RPS7	-7130.0
RPL37A	-7049.0
RPS15A	-7015.0
RPS29	-6975.0
RPL7A	-6925.0
RPL18A	-6838.0
RPL37	-6792.0
EIF2S2	-6392.0
RPL8	-6347.0
RPS13	-6339.0
RPS27L	-6200.0
FNIP1	-6150.0
LAMTOR3	-6075.0
RPL35	-6032.0
RPL23A	-6024.0
RPL27	-5884.0
RPS11	-5850.0
ATF2	-5831.0
RPL29	-5778.0
RRAGA	-5665.0
ATP6V1D	-5424.0
RPL22L1	-5348.0
RPS27	-5318.0
RPL12	-5128.0
FAU	-5092.0
UBA52	-4934.0
ITFG2	-4864.0
ATP6V1E2	-4814.0
ATP6V1G1	-4739.0
KPTN	-4622.0
MLST8	-4535.0
RPL7	-4473.0
ATP6V1A	-4340.0
RPL26L1	-4159.0
RPL13A	-4097.5
SLC38A9	-3580.0
LAMTOR5	-3490.0
RPS5	-3417.0
CEBPG	-3078.0
MIOS	-3026.0
RPL36AL	-2981.5
DEPDC5	-2953.0
RPL14	-2908.0
RPS12	-2751.0
RPS27A	-2707.0
RPS21	-2596.0
ATP6V1G2	-2383.0
ATP6V1B2	-2110.0
ATF4	-1852.0
LAMTOR2	-1828.0
RPL10A	-1720.0
RPL24	-1557.0
ATP6V1H	-1033.0
RPL30	-893.0
SESN1	-765.0
RPS24	-456.0
RPL6	-400.0
FNIP2	-43.0
SEC13	66.0
RPS15	320.0
RPS20	828.0
ATP6V0D2	1300.0
LAMTOR4	1382.0
ATP6V0C	1839.0
ATP6V1B1	1870.0
WDR59	1905.0
RRAGD	2030.0
ATP6V0B	2171.0
RPL21	2253.0
ATP6V0E1	2818.0
NPRL2	2838.0
ATP6V1C1	2965.0
ATF3	3315.0
RPLP2	3532.0
EIF2AK4	3594.0
RPL31	3600.0
NPRL3	3705.0
TRIB3	3731.0
ATP6V1C2	4365.0
ATP6V1E1	4481.0
GCN1	4487.0
SESN2	4709.0
RPL19	4741.0
RPS25	4809.0
SH3BP4	5016.0
ATP6V1G3	5446.0
RPL22	5772.0
ASNS	5979.0
RPS23	6291.0
BMT2	6565.0
SZT2	7334.0
MTOR	7388.0
ATP6V0D1	7429.0
TCIRG1	8335.0
ATP6V1F	8527.0
RPTOR	8745.0
LAMTOR1	9222.0
WDR24	9482.0
IMPACT	9568.0
FLCN	9658.0
RPL3L	9915.0
RPL10L	10108.0

---

REACTOME_NEGATIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION

REACTOME_NEGATIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION

	853
set	REACTOME_NEGATIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION
setSize	100
pANOVA	3.83e-09
s.dist	-0.341
p.adjustANOVA	4.19e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
POLR1E	-10495.0
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
SAP30	-9654.0
H2BC5	-9558.0
TBP	-9553.0
H2AC4	-9538.0
SAP18	-9497.0
H3C3	-9117.0
SIN3A	-9018.0
H2AC7	-8983.5

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
POLR1E	-10495.0
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
SAP30	-9654.0
H2BC5	-9558.0
TBP	-9553.0
H2AC4	-9538.0
SAP18	-9497.0
H3C3	-9117.0
SIN3A	-9018.0
H2AC7	-8983.5
H2BC7	-8983.5
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0
POLR1H	-8215.0
H2BC10	-8128.0
H2AC8	-7580.0
POLR2E	-7485.0
H3C10	-7442.0
TAF1D	-7196.0
H4C6	-7171.0
RRP8	-6863.0
ARID4B	-6686.0
H2BC11	-6443.0
GTF2H3	-6340.0
POLR1C	-6163.0
H3C8	-5893.0
POLR1G	-5845.0
CDK7	-5825.0
H2AJ	-5812.0
H4C12	-5632.0
MNAT1	-5299.0
H4C2	-5172.0
H2BC15	-5136.0
CCNH	-4866.0
H4C4	-4850.0
H3C1	-4828.0
SMARCA5	-4808.0
H2BC8	-4740.0
POLR1F	-4737.0
H2AX	-4613.0
POLR1B	-4549.0
H4C9	-4394.0
H3C6	-4228.0
H2BC12	-3934.0
POLR2F	-3657.0
H2BC6	-3615.0
MBD2	-3520.0
UBTF	-3295.0
H2AC14	-3153.0
H2BC1	-3120.0
GTF2H5	-3090.0
POLR2H	-2710.0
H4C16	-2435.0
H3C11	-2128.0
TTF1	-2113.0
TAF1B	-1985.0
H2BC21	-1800.0
SAP130	-1325.0
POLR1D	-1301.0
SIRT1	-1075.0
H3-3A	-1031.0
H3-3B	-813.0
POLR2K	-624.0
H2AC20	-444.0
POLR2L	-372.0
H4C1	-204.0
HDAC1	78.0
H2BC4	586.0
ERCC2	1041.0
H2BC26	1116.0
DNMT3B	1176.0
GTF2H1	2125.0
POLR1A	2501.0
HDAC2	2992.0
SAP30BP	3191.0
BAZ2A	3715.0
H2AC6	3867.0
H2AZ2	4572.0
TAF1A	4620.0
SIN3B	5045.0
DNMT1	5467.0
GTF2H4	5742.0
SAP30L	5794.0
SUDS3	6117.0
H3C12	6531.0
H3C2	7476.0
TAF1C	8532.0
ERCC3	8718.0
H4C13	8916.0

---

REACTOME_SIRT1_NEGATIVELY_REGULATES_RRNA_EXPRESSION

REACTOME_SIRT1_NEGATIVELY_REGULATES_RRNA_EXPRESSION

	737
set	REACTOME_SIRT1_NEGATIVELY_REGULATES_RRNA_EXPRESSION
setSize	60
pANOVA	4.19e-09
s.dist	-0.438
p.adjustANOVA	4.3e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
TBP	-9553.0
H2AC4	-9538.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
TBP	-9553.0
H2AC4	-9538.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0
H2BC10	-8128.0
H2AC8	-7580.0
H3C10	-7442.0
TAF1D	-7196.0
H4C6	-7171.0
RRP8	-6863.0
H2BC11	-6443.0
H3C8	-5893.0
H2AJ	-5812.0
H4C12	-5632.0
H4C2	-5172.0
H2BC15	-5136.0
H4C4	-4850.0
H3C1	-4828.0
H2BC8	-4740.0
H2AX	-4613.0
H4C9	-4394.0
H3C6	-4228.0
H2BC12	-3934.0
H2BC6	-3615.0
H2AC14	-3153.0
H2BC1	-3120.0
H4C16	-2435.0
H3C11	-2128.0
TAF1B	-1985.0
H2BC21	-1800.0
SIRT1	-1075.0
H3-3A	-1031.0
H3-3B	-813.0
H2AC20	-444.0
H4C1	-204.0
H2BC4	586.0
H2BC26	1116.0
H2AC6	3867.0
H2AZ2	4572.0
TAF1A	4620.0
H3C12	6531.0
H3C2	7476.0
TAF1C	8532.0
H4C13	8916.0

---

REACTOME_CELLULAR_RESPONSES_TO_STIMULI

REACTOME_CELLULAR_RESPONSES_TO_STIMULI

	1314
set	REACTOME_CELLULAR_RESPONSES_TO_STIMULI
setSize	779
pANOVA	5.53e-09
s.dist	-0.123
p.adjustANOVA	5.34e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CCL2	-10628.0
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
RPL39L	-10291.0
H2BC3	-10249.0
CASTOR1	-10229.0
PRDX2	-10200.0
H2BC14	-10180.0
H4C3	-10142.0
GSTA1	-10118.0
RPL18	-10087.0
SEH1L	-10060.0
ATP6V0E2	-10055.0
RPL23	-9997.0
RPL35A	-9988.0
RPL38	-9969.0
H2BC13	-9956.0
IL6	-9934.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CCL2	-10628.0
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
RPL39L	-10291.0
H2BC3	-10249.0
CASTOR1	-10229.0
PRDX2	-10200.0
H2BC14	-10180.0
H4C3	-10142.0
GSTA1	-10118.0
RPL18	-10087.0
SEH1L	-10060.0
ATP6V0E2	-10055.0
RPL23	-9997.0
RPL35A	-9988.0
RPL38	-9969.0
H2BC13	-9956.0
IL6	-9934.0
H2BC9	-9924.5
H3C7	-9924.5
HSPA8	-9899.0
UBE2S	-9874.0
MT1A	-9854.0
CDK4	-9831.0
GFPT1	-9823.0
RPL11	-9821.0
RPS6	-9806.0
CREB3	-9767.0
H4C11	-9725.0
RPS28	-9678.0
RPL27A	-9667.0
ASF1A	-9632.0
COX6B1	-9627.0
RPL34	-9611.0
RPL26	-9600.0
H2BC5	-9558.0
RPL28	-9548.0
H2AC4	-9538.0
TUBA3E	-9534.0
PSMD13	-9525.0
RPS18	-9512.0
RPS26	-9490.0
RPS16	-9467.0
RPL3	-9459.0
RAD50	-9451.0
EXOSC4	-9447.0
HSPA1A	-9425.0
HMOX1	-9422.0
CREB3L4	-9410.0
RPS14	-9401.0
COX16	-9393.0
IDH1	-9372.0
COX5A	-9354.0
CAPZA1	-9343.0
CAPZA3	-9340.0
MIR24-2	-9329.0
GSTA3	-9297.0
HSPA13	-9287.0
PSMB8	-9275.0
NUP42	-9274.0
RPL9	-9273.0
EXOSC8	-9261.0
ERF	-9234.0
NCOA6	-9190.0
NUP43	-9181.0
TUBA1B	-9157.0
SOD2	-9128.0
H3C3	-9117.0
RPL5	-9093.0
RPS10	-9091.0
PSMA7	-9081.0
BRCA1	-9053.0
TRIM21	-9046.0
CSNK2A1	-9019.0
SIN3A	-9018.0
H2AC7	-8983.5
H2BC7	-8983.5
RPS3A	-8975.0
DYNLL1	-8883.0
IL1A	-8881.0
MYC	-8846.0
RPS3	-8834.0
TUBB8	-8723.0
RPL13	-8701.0
RPLP1	-8700.0
CYCS	-8679.0
PSMA3	-8660.0
RPL32	-8650.0
NUP107	-8608.0
HBA1	-8599.0
DNAJC7	-8587.0
HSPA4L	-8545.0
AGO1	-8521.0
CEBPB	-8501.0
COX6C	-8483.0
EGLN2	-8473.0
RPSA	-8467.0
PSMC5	-8460.0
ETS2	-8447.0
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0
HDGF	-8267.0
PSMD4	-8253.0
FKBP5	-8251.0
HSPB8	-8183.0
PTGES3	-8162.0
MAPKAPK2	-8129.0
H2BC10	-8128.0
TERF2IP	-8102.0
DNAJA2	-8100.0
FKBP14	-8079.0
EIF2S1	-8073.0
UBC	-8040.0
TUBA1A	-8015.0
MRPL18	-7989.0
LMNA	-7958.0
NUP37	-7953.0
TGS1	-7901.0
HSP90B1	-7898.0
RPLP0	-7893.0
RPS9	-7845.0
RPL17	-7840.0
YWHAE	-7836.0
RPS19	-7779.0
RPS2	-7738.0
RPL4	-7711.0
PSMB2	-7696.0
NUP160	-7693.0
RPL36	-7654.0
MYDGF	-7651.0
KICS2	-7633.0
DIS3	-7622.0
EXOSC9	-7610.0
H2AC8	-7580.0
DNAJB1	-7572.0
RRAGC	-7551.0
MED1	-7549.0
CALR	-7509.0
CCS	-7505.0
H3C10	-7442.0
RPL41	-7424.0
CREBRF	-7420.0
COX18	-7408.0
KAT5	-7394.0
MT1E	-7392.0
RPS8	-7382.0
SHC1	-7374.0
CDKN2C	-7371.0
SRPRB	-7364.0
RPL15	-7360.0
PSME2	-7342.0
PALB2	-7323.0
HIF3A	-7315.0
COX4I1	-7309.0
DDIT3	-7249.0
HSPB2	-7237.0
RHEB	-7173.0
H4C6	-7171.0
CDC16	-7166.0
PSMB3	-7156.0
PSMA4	-7153.0
RPS7	-7130.0
PSMD7	-7104.0
SKP1	-7085.0
RPL37A	-7049.0
RPS15A	-7015.0
GSK3B	-6981.0
MAP2K3	-6978.0
RPS29	-6975.0
VHL	-6969.0
NRIP1	-6963.0
DEDD2	-6958.0
MAPKAPK5	-6938.0
RPL7A	-6925.0
RPL18A	-6838.0
TERF1	-6818.0
CDC26	-6803.0
RPL37	-6792.0
PSMB9	-6737.0
COX11	-6713.0
CREB3L1	-6712.0
PSMC4	-6700.0
EIF2AK3	-6694.0
ID1	-6671.0
UBE2D3	-6626.0
CDKN2D	-6581.0
NUP50	-6564.0
COX20	-6535.0
IGFBP1	-6529.0
H2BC11	-6443.0
PSMA5	-6442.0
EIF2S2	-6392.0
TXN2	-6388.0
AJUBA	-6355.0
RPL8	-6347.0
RPS13	-6339.0
E2F1	-6323.0
ANAPC1	-6309.0
PSMD11	-6284.0
RPS27L	-6200.0
RPA2	-6177.0
HIF1A	-6157.0
FNIP1	-6150.0
FOS	-6098.0
LAMTOR3	-6075.0
ERN1	-6074.0
CSNK2A2	-6062.0
RPL35	-6032.0
RPL23A	-6024.0
JUN	-5900.0
H3C8	-5893.0
RPL27	-5884.0
EXOSC5	-5874.0
EEF1A1	-5856.0
RPS11	-5850.0
ATF2	-5831.0
XPO1	-5829.0
H2AJ	-5812.0
MAPK10	-5809.0
PRDX3	-5799.0
RPL29	-5778.0
PTK6	-5723.0
TUBAL3	-5667.0
RRAGA	-5665.0
H4C12	-5632.0
HSP90AA1	-5595.0
PSME3	-5547.0
RNF2	-5536.0
SCO2	-5515.0
BLVRA	-5470.0
ATP6V1D	-5424.0
EXTL1	-5360.0
RPL22L1	-5348.0
RPS27	-5318.0
EXOSC7	-5281.0
H4C2	-5172.0
CRYAB	-5161.0
IFNB1	-5159.0
H2BC15	-5136.0
RPL12	-5128.0
HSBP1	-5118.0
H1-4	-5116.0
FAU	-5092.0
UBB	-5059.0
NUP153	-5033.0
TUBB4A	-5016.0
GOSR2	-5010.0
HSP90AB1	-4988.0
HMGA1	-4986.0
KLHDC3	-4976.0
ETS1	-4973.0
TINF2	-4952.0
UBA52	-4934.0
CDKN2A	-4928.0
ITFG2	-4864.0
HSPH1	-4855.0
LIMD1	-4851.0
H4C4	-4850.0
H3C1	-4828.0
ATP6V1E2	-4814.0
PSMB10	-4811.0
EED	-4751.0
H2BC8	-4740.0
ATP6V1G1	-4739.0
LMNB1	-4730.0
AKT1S1	-4728.0
KHSRP	-4714.0
PSMA6	-4676.0
HMOX2	-4671.0
MDM4	-4670.0
AGO3	-4662.0
CHD9	-4654.0
KPTN	-4622.0
H2AX	-4613.0
COX6A1	-4546.0
EP300	-4543.0
MLST8	-4535.0
CDKN2B	-4480.0
RPL7	-4473.0
PSMD9	-4450.0
CSNK2B	-4429.0
H4C9	-4394.0
ATP6V1A	-4340.0
MT3	-4333.0
HIGD1A	-4321.0
DYNC1I1	-4260.0
H3C6	-4228.0
CBX8	-4184.0
GPX1	-4172.0
RPL26L1	-4159.0
MDM2	-4121.0
RPL13A	-4097.5
TFDP2	-4086.0
H2BC12	-3934.0
DNAJB11	-3931.0
SUZ12	-3901.0
BAG1	-3896.0
ANAPC5	-3877.0
TACO1	-3819.0
COX7A2L	-3816.0
PSMD5	-3781.0
ARNT	-3771.0
HBB	-3770.0
CYBA	-3735.0
BAG4	-3684.0
CBX4	-3659.0
DCTN5	-3650.0
DNAJC2	-3648.0
UBE2E1	-3620.0
ACTR10	-3616.0
H2BC6	-3615.0
SLC38A9	-3580.0
TNRC6B	-3506.0
LAMTOR5	-3490.0
MTF1	-3482.0
PSMC2	-3476.0
HSPA1L	-3462.0
HSPA6	-3457.0
PSMA2	-3445.0
NUP155	-3436.0
RPS5	-3417.0
ANAPC10	-3390.0
PSMD6	-3380.0
UBE2D2	-3328.0
EXTL2	-3317.0
GSK3A	-3287.0
PSMB4	-3285.0
CDKN1B	-3253.0
DCP2	-3244.0
H1-2	-3209.0
RBX1	-3208.0
H2AC14	-3153.0
HERPUD1	-3131.0
SRXN1	-3129.0
H2BC1	-3120.0
PSMC3	-3081.0
CEBPG	-3078.0
MIOS	-3026.0
MAP2K7	-2991.0
LRPPRC	-2983.0
RPL36AL	-2981.5
MAPK7	-2978.0
DEPDC5	-2953.0
MT1X	-2943.0
RPL14	-2908.0
ATM	-2904.0
TPR	-2890.0
HYOU1	-2885.0
TXNRD1	-2861.0
ERO1A	-2845.0
IGFBP7	-2842.0
SCO1	-2754.0
RPS12	-2751.0
EGLN1	-2719.0
RPS27A	-2707.0
HSPA1B	-2681.0
RBBP4	-2675.0
CDK6	-2634.0
WTIP	-2598.0
RPS21	-2596.0
KEAP1	-2567.0
PPARGC1A	-2520.0
SERP1	-2503.0
BAG5	-2480.0
H1-3	-2466.0
NUP85	-2443.0
H4C16	-2435.0
CCNE1	-2408.0
PRDX5	-2397.0
ATP6V1G2	-2383.0
SOD1	-2375.0
TXNIP	-2326.0
ALB	-2223.0
ANAPC16	-2166.0
ME1	-2156.0
HSPA12A	-2150.0
H3C11	-2128.0
ATP6V1B2	-2110.0
NR3C2	-2050.0
HSPA12B	-2032.0
SNCB	-2029.0
NPAS2	-1969.0
CCNA2	-1962.0
NUP98	-1888.0
NBN	-1875.0
ATF4	-1852.0
LAMTOR2	-1828.0
H2BC21	-1800.0
PPP2R5B	-1791.0
NFYC	-1772.0
PSMB6	-1764.0
MAFG	-1740.0
RPL10A	-1720.0
TP53	-1704.0
APOB	-1692.0
NR3C1	-1687.0
RORA	-1659.0
CAMK2D	-1646.0
RPL24	-1557.0
TUBA4A	-1528.0
NFKB1	-1523.0
ANAPC11	-1511.0
HSPA5	-1489.0
HSPA14	-1425.0
TBL1XR1	-1412.0
MAPKAPK3	-1391.0
ATOX1	-1254.0
ACADVL	-1241.0
CDK2	-1214.0
DCTN2	-1194.0
E2F3	-1191.0
BMI1	-1182.0
SYVN1	-1177.0
SIRT1	-1075.0
PSMC6	-1062.0
TLN1	-1049.0
CRTC2	-1036.0
ATP6V1H	-1033.0
H3-3A	-1031.0
RELA	-982.0
MAPK11	-896.0
RPL30	-893.0
NCF2	-892.0
GPX6	-868.0
H3-3B	-813.0
SESN1	-765.0
CCNA1	-706.0
XBP1	-660.0
SEC31A	-641.0
TUBB3	-637.0
DNAJC3	-592.0
HSPA2	-580.0
HM13	-541.0
NCOR1	-527.0
RPS24	-456.0
H2AC20	-444.0
DCSTAMP	-403.0
RPL6	-400.0
CAPZA2	-391.0
ACTR1A	-344.0
MAP2K6	-307.0
CREB3L3	-302.0
GCLM	-290.0
NUP58	-237.0
SKP2	-213.0
H4C1	-204.0
CDKN1A	-65.0
BTRC	-46.0
FNIP2	-43.0
COX5B	-40.0
SEM1	-38.0
TPP1	-32.0
HSPA9	-30.0
PSMB1	-28.0
HSPA4	-7.0
SEC13	66.0
YIF1A	134.0
BAG3	161.0
LY96	187.0
PSMA1	296.0
RPS15	320.0
AQP8	366.0
DCTN6	373.0
NUDT2	408.0
BACH1	430.0
NUP35	446.0
NCOA2	526.0
E2F2	573.0
H2BC4	586.0
CAMK2A	600.0
MEF2C	646.0
GPX5	668.0
HIF1AN	724.0
DNAJA1	731.0
RPS20	828.0
NPLOC4	838.0
PARN	927.0
ST13	942.0
MAPK1	981.0
PREB	1031.0
CDC27	1034.0
NOX4	1061.0
GRB10	1066.0
H2BC26	1116.0
ANAPC15	1129.0
COX14	1160.0
PGR	1209.0
DYNC1LI1	1214.0
BLVRB	1218.0
VCP	1230.0
ATP6V0D2	1300.0
EPO	1308.0
SLC7A11	1323.0
NUP88	1334.0
LAMTOR4	1382.0
NDC1	1422.0
PSMB7	1455.0
ELOC	1468.0
UBXN7	1522.0
TLR4	1524.0
NUP214	1526.0
EIF2AK1	1531.0
EDEM1	1559.0
DNAJB9	1566.0
TATDN2	1573.0
PSME4	1583.0
PSMB5	1628.0
GPX8	1662.0
POM121C	1782.0
ATP6V0C	1839.0
PGD	1849.0
ATP6V1B1	1870.0
TUBA1C	1901.0
WDR59	1905.0
EXOSC3	1939.0
TXN	1959.0
DPP3	1960.0
NOX5	2024.0
RRAGD	2030.0
SP1	2034.0
H1-0	2122.0
WFS1	2126.0
EZH2	2131.0
ATP6V0B	2171.0
TNRC6C	2186.0
RPA3	2233.0
VEGFA	2243.0
RPL21	2253.0
BAG2	2273.0
RPS6KA1	2303.0
NUP188	2308.0
HMGA2	2481.0
SRPRA	2535.0
CCNE2	2538.0
MOV10	2631.0
MAP2K4	2792.0
ATF5	2807.0
ATP6V0E1	2818.0
NPRL2	2838.0
CREB3L2	2910.0
ATP6V1C1	2965.0
NUP54	2991.0
TUBB2B	3025.0
NLRP3	3033.0
H1-5	3094.0
STAP2	3123.0
DYNC1I2	3148.0
CUL1	3151.0
ATR	3233.0
ANAPC7	3281.0
ATF3	3315.0
TALDO1	3320.0
TKT	3371.0
NUP133	3395.0
CDC23	3434.0
UFD1	3448.0
NFE2L2	3449.0
MEF2D	3454.0
CAT	3473.0
PRDX6	3523.0
NUP62	3527.0
RPLP2	3532.0
PDIA6	3591.0
EIF2AK4	3594.0
RPL31	3600.0
SQSTM1	3627.0
NDUFA4	3658.0
TUBB4B	3664.0
NPRL3	3705.0
TRIB3	3731.0
CAMK2B	3755.0
AGO4	3763.0
RPA1	3825.0
H2AC6	3867.0
FKBP4	3886.0
COX19	3927.0
CBX6	3963.0
DNAJB6	3969.0
RPS6KA2	3972.0
CLEC1B	4063.0
SOD3	4151.0
APOA1	4203.0
PSMD3	4235.0
PSMC1	4252.0
RAE1	4292.0
STAT3	4311.0
MAP3K5	4355.0
ATP6V1C2	4365.0
TNIK	4370.0
CUL2	4451.0
TUBA3D	4458.0
ATP6V1E1	4481.0
GCN1	4487.0
CTDSP2	4500.0
EXOSC1	4509.0
BMAL1	4538.0
H2AZ2	4572.0
NUP93	4585.0
HIRA	4599.0
AAAS	4604.0
UBN1	4606.0
CREBBP	4616.0
STIP1	4634.0
HSPB1	4649.0
SESN2	4709.0
RPL19	4741.0
MUL1	4766.0
GPX7	4806.0
RPS25	4809.0
MAPK14	4829.0
TXNRD2	4837.0
AKT2	4840.0
CSRP1	4871.0
CLOCK	4971.0
CRTC3	4974.0
NFYA	4977.0
PSMD1	5004.0
SH3BP4	5016.0
TERF2	5034.0
SIN3B	5045.0
H1-1	5053.0
MT2A	5063.0
ELOB	5112.0
MAPK3	5125.0
MBTPS1	5139.0
ACD	5204.5
EGLN3	5222.0
NUP205	5228.0
NR1D1	5257.0
PSMF1	5263.0
P4HB	5278.0
PPP1R15A	5282.0
DCTN4	5283.0
EHMT1	5378.0
CITED2	5389.0
ATP6V1G3	5446.0
MAP1LC3B	5514.0
CUL7	5528.0
PPARA	5586.0
PDIA5	5626.0
UBE2C	5682.0
MT1M	5689.0
SSR1	5709.0
ARFGAP1	5725.0
RPL22	5772.0
CRYBA4	5814.0
PHC3	5835.0
HELZ2	5844.0
RANBP2	5895.0
CAPZB	5950.0
DYNLL2	5970.0
ASNS	5979.0
PRKCD	5998.0
EXOSC6	6019.0
TUBA4B	6021.0
GCLC	6148.0
CAMK2G	6222.0
ATF6	6246.0
MT1G	6276.0
RPS23	6291.0
MAPK9	6293.0
UBE2D1	6348.0
CRTC1	6353.0
CREB1	6384.0
SURF1	6388.0
CXCL8	6479.0
POT1	6490.0
H3C12	6531.0
BMT2	6565.0
ADD1	6583.0
KDELR3	6635.0
HIKESHI	6652.0
RAI1	6734.0
MRE11	6746.0
GML	6750.0
PSMD12	6808.0
CXXC1	6855.0
DCTN3	6913.0
GSTP1	6925.0
CHAC1	6931.0
RPS19BP1	6940.0
HDAC3	6994.0
ABCC1	7025.0
HSF1	7039.0
PSME1	7056.0
POM121	7060.0
TUBB2A	7081.0
MT1B	7126.0
SCMH1	7127.0
PRDX1	7142.0
WIPI1	7286.0
SLC46A1	7287.0
MAP4K4	7316.0
SZT2	7334.0
GSR	7348.0
MTOR	7388.0
ATP6V0D1	7429.0
H3C2	7476.0
EHMT2	7491.0
CARM1	7543.0
NFYB	7596.0
EXOSC2	7600.0
DCTN1	7609.0
AKT3	7612.0
TNFRSF21	7652.0
USP46	7657.0
COX7C	7759.0
TUBB6	7778.0
H3-4	7838.0
MAPK8	7911.0
RB1	7933.0
AKT1	7961.0
ANAPC4	7971.0
EPAS1	8001.0
PSMA8	8011.0
PHC2	8034.0
FBXL17	8109.0
NCOA1	8118.0
TNRC6A	8122.0
EP400	8138.0
FZR1	8219.0
PSMD14	8243.0
KDM6B	8284.0
MT1F	8285.0
ZBTB17	8288.0
TCIRG1	8335.0
CBX2	8371.0
CA9	8447.0
SMARCD3	8471.0
TUBA8	8510.0
ATP6V1F	8527.0
MIR24-1	8555.0
SERPINH1	8654.0
NQO1	8714.0
RPTOR	8745.0
MAFK	8800.0
DNAJA4	8831.0
NOTCH1	8855.0
H4C13	8916.0
CCAR2	8982.0
PHC1	8999.0
VENTX	9003.0
MINK1	9051.0
DYNC1H1	9059.0
CABIN1	9117.0
NCOR2	9123.0
LAMTOR1	9222.0
EXTL3	9252.0
ANAPC2	9292.0
RLN1	9408.0
PSMD8	9422.0
NUP210	9431.0
TUBA3C	9441.0
WDR24	9482.0
NCF4	9494.0
IMPACT	9568.0
DYNC1LI2	9584.0
CUL3	9592.0
FLCN	9658.0
TFDP1	9663.0
RING1	9689.0
GPX3	9722.0
FABP1	9889.0
PSMD2	9891.0
RPL3L	9915.0
GPX2	10031.0
RPL10L	10108.0
COX8A	10114.0
RXRA	10290.0
MT4	10297.0
DDX11	10344.0
HBA2	10390.0
TUBB1	10462.0
MT1H	10528.0
PSMB11	10612.0
PLA2G4B	11017.0

---

REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_HSCS

REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_HSCS

	1282
set	REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_HSCS
setSize	121
pANOVA	1.02e-08
s.dist	-0.301
p.adjustANOVA	9.18e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
PSMD13	-9525.0
PSMB8	-9275.0
H3C3	-9117.0
PSMA7	-9081.0
H2AC7	-8983.5
H2BC7	-8983.5
PSMA3	-8660.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
PSMD13	-9525.0
PSMB8	-9275.0
H3C3	-9117.0
PSMA7	-9081.0
H2AC7	-8983.5
H2BC7	-8983.5
PSMA3	-8660.0
PSMC5	-8460.0
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0
PSMD4	-8253.0
H2BC10	-8128.0
UBC	-8040.0
PSMB2	-7696.0
H2AC8	-7580.0
H3C10	-7442.0
PSME2	-7342.0
H4C6	-7171.0
PSMB3	-7156.0
PSMA4	-7153.0
PSMD7	-7104.0
PSMB9	-6737.0
PSMC4	-6700.0
H2BC11	-6443.0
PSMA5	-6442.0
PSMD11	-6284.0
H3C8	-5893.0
CDK7	-5825.0
H2AJ	-5812.0
H4C12	-5632.0
PSME3	-5547.0
GATA2	-5361.0
CBFB	-5323.0
MNAT1	-5299.0
LDB1	-5289.0
YAP1	-5262.0
H4C2	-5172.0
H2BC15	-5136.0
UBB	-5059.0
UBA52	-4934.0
CCNH	-4866.0
H4C4	-4850.0
H3C1	-4828.0
PSMB10	-4811.0
H2BC8	-4740.0
PSMA6	-4676.0
H2AX	-4613.0
PSMD9	-4450.0
TAL1	-4419.0
H4C9	-4394.0
H3C6	-4228.0
H2BC12	-3934.0
PSMD5	-3781.0
H2BC6	-3615.0
PSMC2	-3476.0
PSMA2	-3445.0
PSMD6	-3380.0
KMT2A	-3359.0
PSMB4	-3285.0
H2AC14	-3153.0
H2BC1	-3120.0
PSMC3	-3081.0
RPS27A	-2707.0
H4C16	-2435.0
H3C11	-2128.0
RUNX1	-1819.0
H2BC21	-1800.0
PSMB6	-1764.0
ITCH	-1575.0
MYB	-1291.0
PSMC6	-1062.0
LMO1	-1044.0
H3-3A	-1031.0
H3-3B	-813.0
H2AC20	-444.0
H4C1	-204.0
SEM1	-38.0
PSMB1	-28.0
PSMA1	296.0
H2BC4	586.0
H2BC26	1116.0
ABL1	1449.0
PSMB7	1455.0
PSME4	1583.0
PSMB5	1628.0
TP73	2799.0
SPI1	3035.0
H2AC6	3867.0
TCF12	4145.0
PSMD3	4235.0
PSMC1	4252.0
H2AZ2	4572.0
LMO2	4887.0
PSMD1	5004.0
PSMF1	5263.0
H3C12	6531.0
PSMD12	6808.0
PSME1	7056.0
GATA3	7270.0
H3C2	7476.0
PSMA8	8011.0
PSMD14	8243.0
H4C13	8916.0
PSMD8	9422.0
TCF3	9438.0
PSMD2	9891.0
PSMB11	10612.0

---

REACTOME_DNA_REPLICATION_PRE_INITIATION

REACTOME_DNA_REPLICATION_PRE_INITIATION

	1101
set	REACTOME_DNA_REPLICATION_PRE_INITIATION
setSize	150
pANOVA	1.06e-08
s.dist	-0.271
p.adjustANOVA	9.18e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
POLE3	-10268.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
MCM5	-9967.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
UBE2S	-9874.0
H4C11	-9725.0
POLE4	-9697.0
H2BC5	-9558.0
H2AC4	-9538.0
PSMD13	-9525.0
PSMB8	-9275.0
H3C3	-9117.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
POLE3	-10268.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
MCM5	-9967.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
UBE2S	-9874.0
H4C11	-9725.0
POLE4	-9697.0
H2BC5	-9558.0
H2AC4	-9538.0
PSMD13	-9525.0
PSMB8	-9275.0
H3C3	-9117.0
PSMA7	-9081.0
H2AC7	-8983.5
H2BC7	-8983.5
PSMA3	-8660.0
PSMC5	-8460.0
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0
PSMD4	-8253.0
H2BC10	-8128.0
UBC	-8040.0
PSMB2	-7696.0
H2AC8	-7580.0
KPNB1	-7455.0
H3C10	-7442.0
PSME2	-7342.0
H4C6	-7171.0
CDC16	-7166.0
PSMB3	-7156.0
PSMA4	-7153.0
DBF4	-7142.0
PSMD7	-7104.0
CDC26	-6803.0
PSMB9	-6737.0
PSMC4	-6700.0
H2BC11	-6443.0
PSMA5	-6442.0
MCM8	-6337.0
ANAPC1	-6309.0
PSMD11	-6284.0
RPA2	-6177.0
POLA2	-5905.0
H3C8	-5893.0
H2AJ	-5812.0
H4C12	-5632.0
PSME3	-5547.0
KPNA1	-5353.0
H4C2	-5172.0
H2BC15	-5136.0
UBB	-5059.0
UBA52	-4934.0
H4C4	-4850.0
H3C1	-4828.0
PSMB10	-4811.0
H2BC8	-4740.0
MCM6	-4722.0
PSMA6	-4676.0
H2AX	-4613.0
PRIM2	-4490.0
PSMD9	-4450.0
H4C9	-4394.0
H3C6	-4228.0
ORC1	-4115.0
ORC2	-3938.0
H2BC12	-3934.0
ANAPC5	-3877.0
PSMD5	-3781.0
UBE2E1	-3620.0
H2BC6	-3615.0
PSMC2	-3476.0
PSMA2	-3445.0
MCM4	-3404.0
ANAPC10	-3390.0
PSMD6	-3380.0
PSMB4	-3285.0
H2AC14	-3153.0
MCM10	-3137.0
H2BC1	-3120.0
PSMC3	-3081.0
RPS27A	-2707.0
H4C16	-2435.0
ANAPC16	-2166.0
CDC6	-2152.0
H3C11	-2128.0
H2BC21	-1800.0
PSMB6	-1764.0
ORC3	-1754.0
ANAPC11	-1511.0
CDK2	-1214.0
PRIM1	-1066.0
PSMC6	-1062.0
H3-3A	-1031.0
H3-3B	-813.0
H2AC20	-444.0
H4C1	-204.0
SEM1	-38.0
PSMB1	-28.0
PSMA1	296.0
MCM3	342.0
H2BC4	586.0
ORC5	821.0
CDC27	1034.0
CDC7	1087.0
H2BC26	1116.0
ANAPC15	1129.0
PSMB7	1455.0
CDT1	1607.0
PSMB5	1628.0
GMNN	1922.0
RPA3	2233.0
ORC4	2489.0
MCM7	3207.0
ANAPC7	3281.0
CDC23	3434.0
RPA1	3825.0
H2AC6	3867.0
PSMD3	4235.0
PSMC1	4252.0
KPNA6	4371.0
H2AZ2	4572.0
PSMD1	5004.0
PSMF1	5263.0
UBE2C	5682.0
UBE2D1	6348.0
POLE2	6363.0
ORC6	6395.0
H3C12	6531.0
PSMD12	6808.0
CDC45	7024.0
PSME1	7056.0
H3C2	7476.0
ANAPC4	7971.0
FZR1	8219.0
PSMD14	8243.0
POLE	8419.0
H4C13	8916.0
ANAPC2	9292.0
PSMD8	9422.0
MCM2	9504.0
PSMD2	9891.0

---

REACTOME_ASSEMBLY_OF_THE_ORC_COMPLEX_AT_THE_ORIGIN_OF_REPLICATION

REACTOME_ASSEMBLY_OF_THE_ORC_COMPLEX_AT_THE_ORIGIN_OF_REPLICATION

	1091
set	REACTOME_ASSEMBLY_OF_THE_ORC_COMPLEX_AT_THE_ORIGIN_OF_REPLICATION
setSize	62
pANOVA	1.29e-08
s.dist	-0.418
p.adjustANOVA	9.83e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0
H2BC10	-8128.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0
H2BC10	-8128.0
H2AC8	-7580.0
KPNB1	-7455.0
H3C10	-7442.0
H4C6	-7171.0
H2BC11	-6443.0
H3C8	-5893.0
H2AJ	-5812.0
H4C12	-5632.0
KPNA1	-5353.0
H4C2	-5172.0
H2BC15	-5136.0
H4C4	-4850.0
H3C1	-4828.0
H2BC8	-4740.0
H2AX	-4613.0
H4C9	-4394.0
H3C6	-4228.0
ORC1	-4115.0
ORC2	-3938.0
H2BC12	-3934.0
H2BC6	-3615.0
H2AC14	-3153.0
H2BC1	-3120.0
H4C16	-2435.0
H3C11	-2128.0
H2BC21	-1800.0
ORC3	-1754.0
H3-3A	-1031.0
H3-3B	-813.0
H2AC20	-444.0
H4C1	-204.0
H2BC4	586.0
ORC5	821.0
H2BC26	1116.0
ORC4	2489.0
H2AC6	3867.0
KPNA6	4371.0
H2AZ2	4572.0
ORC6	6395.0
H3C12	6531.0
H3C2	7476.0
H4C13	8916.0

---

REACTOME_MEIOTIC_RECOMBINATION

REACTOME_MEIOTIC_RECOMBINATION

	1433
set	REACTOME_MEIOTIC_RECOMBINATION
setSize	80
pANOVA	1.3e-08
s.dist	-0.368
p.adjustANOVA	9.83e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
MSH4	-9933.0
H2BC9	-9924.5
H3C7	-9924.5
CDK4	-9831.0
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
RAD50	-9451.0
H3C3	-9117.0
BRCA1	-9053.0
H2AC7	-8983.5
H2BC7	-8983.5

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
MSH4	-9933.0
H2BC9	-9924.5
H3C7	-9924.5
CDK4	-9831.0
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
RAD50	-9451.0
H3C3	-9117.0
BRCA1	-9053.0
H2AC7	-8983.5
H2BC7	-8983.5
SPO11	-8732.0
BRCA2	-8726.0
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0
H2BC10	-8128.0
H2AC8	-7580.0
H3C10	-7442.0
RAD51C	-7228.0
H4C6	-7171.0
H2BC11	-6443.0
RPA2	-6177.0
H3C8	-5893.0
H2AJ	-5812.0
H4C12	-5632.0
H4C2	-5172.0
H2BC15	-5136.0
H4C4	-4850.0
H3C1	-4828.0
H2BC8	-4740.0
H2AX	-4613.0
RBBP8	-4437.0
H4C9	-4394.0
H3C6	-4228.0
H2BC12	-3934.0
H2BC6	-3615.0
RAD51	-3603.0
H2AC14	-3153.0
H2BC1	-3120.0
ATM	-2904.0
MLH1	-2713.0
H4C16	-2435.0
H3C11	-2128.0
NBN	-1875.0
H2BC21	-1800.0
CDK2	-1214.0
H3-3A	-1031.0
PSMC3IP	-883.0
H3-3B	-813.0
H2AC20	-444.0
MND1	-236.0
H4C1	-204.0
MSH5	-9.0
BLM	541.0
H2BC4	586.0
H2BC26	1116.0
TEX15	1381.0
RPA3	2233.0
DMC1	2773.0
RPA1	3825.0
H2AC6	3867.0
H2AZ2	4572.0
PRDM9	4850.0
TOP3A	6257.0
H3C12	6531.0
MLH3	6715.0
MRE11	6746.0
H3C2	7476.0
H3-4	7838.0
H4C13	8916.0

---

REACTOME_ACTIVATED_PKN1_STIMULATES_TRANSCRIPTION_OF_AR_ANDROGEN_RECEPTOR_REGULATED_GENES_KLK2_AND_KLK3

REACTOME_ACTIVATED_PKN1_STIMULATES_TRANSCRIPTION_OF_AR_ANDROGEN_RECEPTOR_REGULATED_GENES_KLK2_AND_KLK3

	916
set	REACTOME_ACTIVATED_PKN1_STIMULATES_TRANSCRIPTION_OF_AR_ANDROGEN_RECEPTOR_REGULATED_GENES_KLK2_AND_KLK3
setSize	59
pANOVA	1.32e-08
s.dist	-0.428
p.adjustANOVA	9.83e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
KLK3	-10052.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
KLK3	-10052.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0
H2BC10	-8128.0
H2AC8	-7580.0
H3C10	-7442.0
H4C6	-7171.0
PKN1	-6492.0
H2BC11	-6443.0
H3C8	-5893.0
H2AJ	-5812.0
H4C12	-5632.0
H4C2	-5172.0
H2BC15	-5136.0
H4C4	-4850.0
H3C1	-4828.0
H2BC8	-4740.0
H2AX	-4613.0
H4C9	-4394.0
H3C6	-4228.0
H2BC12	-3934.0
H2BC6	-3615.0
H2AC14	-3153.0
H2BC1	-3120.0
H4C16	-2435.0
H3C11	-2128.0
H2BC21	-1800.0
H3-3A	-1031.0
H3-3B	-813.0
H2AC20	-444.0
H4C1	-204.0
NCOA2	526.0
H2BC4	586.0
H2BC26	1116.0
KDM1A	2071.0
H2AC6	3867.0
H2AZ2	4572.0
KDM4C	4820.0
H3C12	6531.0
KLK2	7214.0
H3C2	7476.0
H4C13	8916.0

---

REACTOME_INFECTIOUS_DISEASE

REACTOME_INFECTIOUS_DISEASE

	974
set	REACTOME_INFECTIOUS_DISEASE
setSize	910
pANOVA	1.4e-08
s.dist	-0.111
p.adjustANOVA	9.99e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IFNA8	-10817.0
IFNA21	-10738.0
CD3G	-10650.0
SFN	-10645.0
H2AC18	-10545.5
H2AC19	-10545.5
ZCRB1	-10430.0
IFNA16	-10414.0
H2BC17	-10413.0
BECN1	-10364.0
VPS37D	-10354.0
H4C8	-10347.0
RPL39L	-10291.0
H2BC3	-10249.0
TAF15	-10246.0
H2BC14	-10180.0
POLR2J	-10179.0
H4C3	-10142.0
H2AC17	-10139.0
CHMP4C	-10126.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IFNA8	-10817.0
IFNA21	-10738.0
CD3G	-10650.0
SFN	-10645.0
H2AC18	-10545.5
H2AC19	-10545.5
ZCRB1	-10430.0
IFNA16	-10414.0
H2BC17	-10413.0
BECN1	-10364.0
VPS37D	-10354.0
H4C8	-10347.0
RPL39L	-10291.0
H2BC3	-10249.0
TAF15	-10246.0
H2BC14	-10180.0
POLR2J	-10179.0
H4C3	-10142.0
H2AC17	-10139.0
CHMP4C	-10126.0
RPL18	-10087.0
SEH1L	-10060.0
RPL23	-9997.0
RPL35A	-9988.0
H2AC11	-9981.0
RPL38	-9969.0
H2BC13	-9956.0
IL6	-9934.0
TAF9	-9926.0
H2BC9	-9924.5
H3C7	-9924.5
TUFM	-9885.0
POLR2I	-9848.0
LCK	-9835.0
RPL11	-9821.0
RPS6	-9806.0
IFNA1	-9797.0
GNG3	-9749.0
H4C11	-9725.0
RPS28	-9678.0
RPL27A	-9667.0
GTF2E1	-9662.0
SAP30	-9654.0
RPL34	-9611.0
RPL26	-9600.0
SMAD4	-9585.0
HNRNPA1	-9569.0
H2BC5	-9558.0
TBP	-9553.0
RPL28	-9548.0
CCR5	-9546.0
H2AC4	-9538.0
TUBA3E	-9534.0
PSMD13	-9525.0
RPS18	-9512.0
SAP18	-9497.0
FXYD3	-9492.0
RPS26	-9490.0
TUSC3	-9484.0
RPS16	-9467.0
RPL3	-9459.0
HSPA1A	-9425.0
HMOX1	-9422.0
RNMT	-9412.0
RPS14	-9401.0
SNRPD2	-9397.0
G3BP1	-9322.0
PYCARD	-9319.0
ARID4A	-9299.0
GEMIN5	-9279.0
PSMB8	-9275.0
NUP42	-9274.0
RPL9	-9273.0
SEC24A	-9243.0
TLR9	-9221.0
TSG101	-9209.0
PTPN6	-9208.0
NUP43	-9181.0
CORO1A	-9169.0
TUBA1B	-9157.0
H3C3	-9117.0
RPL5	-9093.0
RPS10	-9091.0
PARP10	-9082.0
PSMA7	-9081.0
H2AC7	-8983.5
H2BC7	-8983.5
RPS3A	-8975.0
HMG20B	-8919.0
DYNLL1	-8883.0
IL1A	-8881.0
RPS3	-8834.0
PPIA	-8791.0
TUBB8	-8723.0
NCKAP1L	-8705.0
RPL13	-8701.0
RPLP1	-8700.0
TAF6	-8676.0
PSMA3	-8660.0
RPL32	-8650.0
NUP107	-8608.0
IL10	-8543.0
GEMIN2	-8513.0
DDX20	-8485.0
SFPQ	-8471.0
RPSA	-8467.0
PSMC5	-8460.0
YWHAZ	-8450.0
ATP1B1	-8444.0
ATG14	-8414.0
ACTB	-8412.0
H4C5	-8410.0
H3C4	-8401.0
CD79B	-8386.0
TUBB	-8344.0
PSMD4	-8253.0
HLA-E	-8224.0
ARPC5	-8216.0
ISG15	-8165.0
PTGES3	-8162.0
REST	-8152.0
CD79A	-8146.0
SUPT4H1	-8138.0
H2BC10	-8128.0
GGT5	-8105.0
FGR	-8084.0
ZDHHC5	-8082.0
DPEP3	-8071.0
H2AC13	-8049.0
UBC	-8040.0
TAF12	-8022.0
TUBA1A	-8015.0
ATP1B2	-8011.0
VAMP1	-7961.0
NUP37	-7953.0
CLTA	-7950.0
FEN1	-7941.0
FXYD7	-7916.0
RPLP0	-7893.0
B2M	-7885.0
RPS9	-7845.0
RPL17	-7840.0
YWHAE	-7836.0
KPNA4	-7797.0
RPS19	-7779.0
ANO4	-7777.0
HLA-B	-7773.0
RPS2	-7738.0
WASF2	-7713.0
RPL4	-7711.0
PSMB2	-7696.0
NUP160	-7693.0
ANO3	-7680.0
CD8B	-7678.0
RPL36	-7654.0
H2AC8	-7580.0
NFKB2	-7578.0
SDC3	-7546.0
PARP1	-7536.0
CALR	-7509.0
IRF3	-7495.0
POLR2E	-7485.0
CHMP1A	-7463.0
KPNB1	-7455.0
TAF11	-7449.0
H3C10	-7442.0
RPL41	-7424.0
SUGT1	-7390.0
NPM1	-7384.0
RPS8	-7382.0
RPL15	-7360.0
ATP1A3	-7356.0
PSME2	-7342.0
TRAF6	-7314.0
ABI1	-7301.0
HCK	-7274.0
MAP2K1	-7272.0
RPN1	-7172.0
H4C6	-7171.0
PSMB3	-7156.0
PSMA4	-7153.0
RPS7	-7130.0
CHMP4B	-7128.0
PSMD7	-7104.0
SKP1	-7085.0
RPL37A	-7049.0
LTF	-7046.0
GNG2	-7031.0
AP1G1	-7022.0
RPS15A	-7015.0
GNB2	-7009.0
SSRP1	-6990.0
ARPC3	-6986.0
GSK3B	-6981.0
MAP2K3	-6978.0
RPS29	-6975.0
VHL	-6969.0
NOXA1	-6956.0
HBEGF	-6941.0
BLNK	-6933.0
RPL7A	-6925.0
S1PR1	-6905.0
IFIH1	-6877.0
RPL18A	-6838.0
RPL37	-6792.0
PSMB9	-6737.0
TGFB1	-6722.0
PSMC4	-6700.0
ARID4B	-6686.0
ISCU	-6685.0
CD163	-6678.0
BST2	-6673.0
SNRPG	-6599.0
UBE2V1	-6594.0
RIGI	-6593.0
TLR1	-6592.0
BANF1	-6589.0
NUP50	-6564.0
SNRPD1	-6546.0
CRBN	-6532.0
GATAD2B	-6523.0
H2BC11	-6443.0
PSMA5	-6442.0
GUCY2C	-6399.0
GPC5	-6387.0
JAK1	-6365.0
RPL8	-6347.0
GTF2H3	-6340.0
RPS13	-6339.0
PSMD11	-6284.0
DVL2	-6228.0
SV2B	-6221.0
RPN2	-6204.0
RPS27L	-6200.0
PSTPIP1	-6195.0
GNG10	-6179.0
TRIM4	-6170.0
TRIM25	-6160.0
SNRPD3	-6155.0
PAK2	-6147.0
WIPF3	-6144.0
H2AC15	-6141.0
PRKCSH	-6110.0
CCNT2	-6104.0
CNBP	-6102.0
NMI	-6068.0
RPL35	-6032.0
UBAP1	-6026.0
RPL23A	-6024.0
UBE2N	-6001.0
DAD1	-5977.0
PTPN11	-5953.0
JUN	-5900.0
H3C8	-5893.0
RPL27	-5884.0
EEF1A1	-5856.0
RPS11	-5850.0
XPO1	-5829.0
CDK7	-5825.0
CTSG	-5802.0
TAF10	-5784.0
RPL29	-5778.0
TOMM70	-5766.0
SUPT16H	-5742.0
GNG4	-5719.0
IMPDH2	-5688.0
TUBAL3	-5667.0
ADCY2	-5659.0
CANX	-5651.0
H4C12	-5632.0
BCL2L1	-5613.0
HSP90AA1	-5595.0
VPS18	-5577.0
PSME3	-5547.0
H2AC21	-5508.0
SH3GL3	-5506.0
MAP3K7	-5505.0
SEC23A	-5498.0
KPNA1	-5353.0
RPL22L1	-5348.0
PDCD6IP	-5325.0
RPS27	-5318.0
TCEA1	-5305.0
MNAT1	-5299.0
CHMP5	-5293.0
GEMIN6	-5280.0
NOD1	-5215.0
H4C2	-5172.0
GPC2	-5169.0
FYN	-5164.0
IFNB1	-5159.0
H2BC15	-5136.0
RPL12	-5128.0
IFNAR1	-5109.0
CDC42	-5100.0
FAU	-5092.0
UBB	-5059.0
ATP1A1	-5034.0
NUP153	-5033.0
TUBB4A	-5016.0
PIK3R4	-4993.0
HSP90AB1	-4988.0
HMGA1	-4986.0
NMT2	-4958.0
UBA52	-4934.0
MASP1	-4889.0
VPS41	-4881.0
CCNH	-4866.0
H4C4	-4850.0
CCNT1	-4829.0
H3C1	-4828.0
RIPK2	-4816.0
PSMB10	-4811.0
RAN	-4756.0
EED	-4751.0
MVB12A	-4746.0
H2BC8	-4740.0
CHMP6	-4716.0
GNG8	-4706.0
PSMA6	-4676.0
POLR2C	-4652.0
CBL	-4646.0
TAF5	-4614.0
CBX1	-4602.0
EP300	-4543.0
PLK2	-4511.0
ENTPD1	-4485.0
RPL7	-4473.0
PALS1	-4465.0
PSMD9	-4450.0
HLA-F	-4424.0
H4C9	-4394.0
GRB2	-4383.0
DDX5	-4382.0
GPC6	-4328.0
BRK1	-4312.0
TAF13	-4272.0
DYNC1I1	-4260.0
H3C6	-4228.0
GJA1	-4176.0
RPL26L1	-4159.0
GPS2	-4154.0
RPL13A	-4097.5
GRSF1	-4077.0
GNAI3	-4041.0
CXCR4	-4018.0
ARPC2	-4010.0
H2BC12	-3934.0
ACTG1	-3932.0
ANTXR1	-3919.0
SUZ12	-3901.0
WASF3	-3860.0
ADCY8	-3858.0
PIK3C3	-3842.0
PSMD5	-3781.0
SIGMAR1	-3740.0
CYBA	-3735.0
XRCC6	-3692.0
POLR2F	-3657.0
H2BC6	-3615.0
ARF1	-3590.0
TBK1	-3566.0
ARPC4	-3537.0
VAV1	-3497.0
PSMC2	-3476.0
NLRP12	-3460.0
PSMA2	-3445.0
NUP155	-3436.0
RPS5	-3417.0
IMPDH1	-3416.0
CLTC	-3396.0
ANO2	-3392.0
PSMD6	-3380.0
EPS15	-3319.0
GSK3A	-3287.0
CHMP2A	-3286.0
PSMB4	-3285.0
WIPF2	-3240.0
MYO10	-3215.0
RBX1	-3208.0
FXYD6	-3173.0
H2AC14	-3153.0
H2BC1	-3120.0
NCKAP1	-3105.0
GTF2H5	-3090.0
PSMC3	-3081.0
WASL	-3071.0
P2RX7	-3021.0
MAP2K7	-2991.0
MGAT2	-2981.5
RPL36AL	-2981.5
GNG7	-2965.0
SV2A	-2959.0
ACTR3	-2948.0
VPS45	-2926.0
RPL14	-2908.0
TPR	-2890.0
TXNRD1	-2861.0
SH3GL2	-2797.0
RPS12	-2751.0
IL1R1	-2714.0
POLR2H	-2710.0
RPS27A	-2707.0
RBBP4	-2675.0
PATJ	-2667.0
RAB5A	-2656.0
JAK3	-2640.0
MGAT1	-2602.0
RPS21	-2596.0
STING1	-2576.0
KEAP1	-2567.0
KPNA5	-2456.0
NUP85	-2443.0
H4C16	-2435.0
CTNNB1	-2416.0
PRKAR1A	-2409.0
PSIP1	-2394.0
WNT5A	-2385.0
STT3A	-2373.0
TXNIP	-2326.0
ELOA	-2318.0
EGFR	-2253.0
AHCYL1	-2205.0
VPS39	-2133.0
H3C11	-2128.0
H2AC1	-2117.0
CAV1	-2025.0
ZDHHC20	-2004.0
GOLGA7	-1972.0
PKLR	-1968.0
NUP98	-1888.0
LYN	-1822.0
RUNX1	-1819.0
H2BC21	-1800.0
STX1A	-1797.0
PSMB6	-1764.0
GTF2A1	-1752.0
RPL10A	-1720.0
NR3C1	-1687.0
MAVS	-1656.0
RCAN3	-1641.0
SAR1B	-1634.0
ITCH	-1575.0
POLR2G	-1573.0
RPL24	-1557.0
TUBA4A	-1528.0
NFKB1	-1523.0
FUT8	-1521.0
HLA-G	-1457.0
TMPRSS2	-1446.0
AP1M2	-1441.0
VPS33A	-1440.0
ADCY6	-1430.0
TBL1XR1	-1412.0
SNRPF	-1314.0
HSPG2	-1279.0
GNAI2	-1251.0
VAV2	-1229.0
VAMP2	-1180.0
NCK1	-1111.0
PPIH	-1067.0
SUMO1	-1063.0
PSMC6	-1062.0
ATP6V1H	-1033.0
CBLL1	-1013.0
GNG11	-1008.0
RELA	-982.0
ADORA2B	-937.0
SV2C	-899.0
RPL30	-893.0
AP2S1	-816.0
IPO5	-800.0
SYK	-772.0
GNG5	-741.0
IRF7	-707.0
NMT1	-700.0
PRMT1	-671.0
ZDHHC2	-650.0
TUBB3	-637.0
POLR2K	-624.0
PABPN1	-616.0
DNAJC3	-592.0
XRCC4	-571.0
ADCY1	-535.0
NCOR1	-527.0
FXYD4	-510.0
TJP1	-487.0
YES1	-478.0
RPS24	-456.0
H2AC20	-444.0
VTA1	-443.0
RPL6	-400.0
KPNA7	-385.0
POLR2L	-372.0
CHMP3	-349.0
MAP2K6	-307.0
NELFB	-301.0
AP1S3	-259.0
ELMO2	-247.0
NUP58	-237.0
ST6GALNAC2	-207.0
H4C1	-204.0
PRKAR2B	-189.0
GALNT1	-155.0
BTRC	-46.0
SEM1	-38.0
PSMB1	-28.0
IL6R	18.0
SEC13	66.0
HDAC1	78.0
PACS1	85.0
PPIG	217.0
ST3GAL2	241.0
ANO9	242.0
SRPK1	260.0
MGAT4A	278.0
PSMA1	296.0
RPS15	320.0
DDOST	322.0
MTA3	331.0
APP	339.0
SIKE1	357.0
VPS25	387.0
ANO1	424.0
GANAB	426.0
NUP35	446.0
PML	514.0
MYO1C	544.0
H2BC4	586.0
RCOR1	593.0
C3AR1	605.0
H2AC12	616.0
CDK9	714.0
ROCK1	745.0
RAB7A	770.0
RPS20	828.0
CSNK1A1	829.0
VPS11	874.0
ACTR2	891.0
HNRNPK	936.0
MAPK1	981.0
SNF8	1007.0
ERCC2	1041.0
PRKACB	1045.0
PRKAR2A	1057.0
VAV3	1082.0
H2BC26	1116.0
TRIM28	1125.0
NCBP1	1140.0
SLC25A4	1169.0
SYT1	1211.0
DYNC1LI1	1214.0
VCP	1230.0
YWHAH	1231.0
ITGA4	1255.0
GNB5	1276.0
ST3GAL1	1319.0
NUP88	1334.0
PLCG2	1363.0
GNAS	1407.0
PDCD1	1408.0
NDC1	1422.0
GTF2E2	1432.0
ABL1	1449.0
FZD7	1451.0
PSMB7	1455.0
HLA-C	1459.0
ELOC	1468.0
H2AC16	1482.0
NUP214	1526.0
PTK2	1567.0
PSME4	1583.0
PSMB5	1628.0
TAF1L	1652.0
LARP1	1707.0
FNTB	1724.0
TAF7	1738.0
POM121C	1782.0
YWHAB	1794.0
G3BP2	1797.0
ANO6	1844.0
NRP1	1855.0
NEDD4L	1865.0
GTF2A2	1895.0
TUBA1C	1901.0
PARP14	1930.0
ANO5	1941.0
STAM2	1943.0
TXN	1959.0
SP1	2034.0
PHF21A	2035.0
PRKACA	2053.0
KDM1A	2071.0
HAVCR1	2089.0
MYH9	2092.0
GNB4	2096.0
XRCC5	2102.0
GEMIN7	2106.0
CDH1	2121.0
GTF2H1	2125.0
EZH2	2131.0
HLA-A	2160.0
ATP1B3	2174.0
DVL1	2218.0
VEGFA	2243.0
RPL21	2253.0
RNGTT	2283.0
FNTA	2285.0
CD28	2290.0
NUP188	2308.0
CD247	2343.0
VPS37A	2358.0
ST6GALNAC4	2369.0
ST6GALNAC3	2370.0
GNGT2	2385.0
ANO8	2438.0
GNG13	2519.0
SEC24C	2525.0
VPS4B	2560.0
MET	2643.0
NCBP2	2717.0
YWHAQ	2738.0
WIPF1	2787.0
MAP2K4	2792.0
H2AC25	2805.0
ITPR2	2849.0
YWHAG	2854.0
COMT	2863.0
CALM1	2882.0
PARP4	2905.0
IRAK2	2911.0
NUP54	2991.0
HDAC2	2992.0
ELMO1	3000.0
KPNA2	3004.0
TUBB2B	3025.0
NLRP3	3033.0
SEC24D	3072.0
ARPC1A	3086.0
IFNGR2	3107.0
DAXX	3128.0
DYNC1I2	3148.0
ADCY9	3190.0
VPS36	3218.0
SDC2	3237.0
UVRAG	3259.0
AP2B1	3275.0
EIF2AK2	3299.0
KPNA3	3312.0
EEF2	3343.0
MTA2	3356.0
NUP133	3395.0
IFNGR1	3407.0
IFNA2	3413.0
GNAT3	3432.0
NFE2L2	3449.0
TAF3	3452.0
MEFV	3503.0
NUP62	3527.0
RPLP2	3532.0
SEC24B	3564.0
RPL31	3600.0
PPIB	3603.0
UBE2I	3611.0
CD9	3663.0
TUBB4B	3664.0
RHBDF2	3708.0
ABI2	3709.0
STAT1	3784.0
TRIM27	3815.0
ELL	3831.0
CASP1	3859.0
H2AC6	3867.0
PCBP2	3870.0
AGRN	3872.0
AP1S1	3873.0
FKBP4	3886.0
ENTPD5	3889.0
GTF2F1	3903.0
PLCG1	3910.0
ZDHHC8	3958.0
FKBP1A	3983.0
GTF2F2	3988.0
DOCK2	4006.0
BRMS1	4051.0
PARP8	4109.0
SRC	4122.0
RCC1	4152.0
CRB3	4165.0
BAIAP2	4194.0
IL18	4213.0
PSMD3	4235.0
PSMC1	4252.0
RAE1	4292.0
LIG4	4330.0
IL1B	4347.0
SMN1	4401.5
SMN2	4401.5
SRPK2	4414.0
RANBP1	4449.0
NT5E	4452.0
TUBA3D	4458.0
SNAP25	4464.0
DPEP2	4474.0
ADCY5	4502.0
MGAT5	4503.0
IL17RC	4535.0
WASF1	4566.0
NUP93	4585.0
AAAS	4604.0
ADAM17	4611.0
CREBBP	4616.0
STAM	4622.0
RPL19	4741.0
SOS1	4758.0
RPS25	4809.0
MAPK14	4829.0
ST3GAL3	4830.0
AKT2	4840.0
RNF135	4866.0
MYO5A	4875.0
TLR2	4879.0
ITPR1	4882.0
ROCK2	4931.0
DOCK1	4967.0
MASP2	4978.0
PSMD1	5004.0
GATAD2A	5020.0
GGT1	5024.0
MYO9B	5078.0
ELOB	5112.0
MAPK3	5125.0
CRK	5157.0
NOS2	5178.0
POLR2D	5189.0
NUP205	5228.0
PSMF1	5263.0
VPS28	5306.0
MAN1B1	5310.0
IKBKB	5332.0
DUSP16	5337.0
CHD4	5360.0
MGAT4C	5463.0
STAT2	5480.0
LIG1	5490.0
MAP1LC3B	5514.0
PARP9	5521.0
NCKIPSD	5547.0
ZBP1	5563.0
TAB2	5618.0
NFKBIA	5710.0
POLR2B	5721.0
ARPC1B	5733.0
ZDHHC3	5739.0
GTF2H4	5742.0
ANO7	5746.0
RPL22	5772.0
SAP30L	5794.0
JAK2	5800.0
TAF4B	5845.0
ITGB1	5860.0
IFNA7	5870.0
CD4	5874.0
SDC1	5875.0
RANBP2	5895.0
MOGS	5934.0
DYNLL2	5970.0
SNRPB	5980.0
NELFCD	5990.0
TUBA4B	6021.0
GNG12	6046.0
FXYD1	6098.0
SUDS3	6117.0
GNAI1	6135.0
SNRPE	6152.0
EDEM2	6162.0
AP2A1	6218.0
ZDHHC11	6233.0
CHMP7	6267.0
RIPK3	6287.0
RPS23	6291.0
GSDMD	6308.0
RAC1	6313.0
GNB1	6330.0
ITPR3	6360.0
CREB1	6384.0
GTF2B	6401.0
VPS4A	6507.0
RANGAP1	6511.0
PDPK1	6520.0
H3C12	6531.0
SMAD3	6552.0
VPS33B	6587.0
CTNND1	6661.0
IFNA13	6676.0
VPS16	6697.0
VPS37C	6765.0
MYH2	6768.0
TRAF3	6798.0
PSMD12	6808.0
CYFIP2	6832.0
ENO1	6907.0
ST3GAL4	6914.0
TYK2	6978.0
HDAC3	6994.0
POLR2A	7019.0
PSME1	7056.0
POM121	7060.0
SUPT5H	7080.0
TUBB2A	7081.0
P2RX4	7177.0
CHMP4A	7212.0
IL17A	7278.0
IFNAR2	7325.0
ADCY7	7350.0
FURIN	7428.0
H3C2	7476.0
TAF4	7507.0
CYFIP1	7535.0
NELFE	7577.0
TKFC	7585.0
CCNK	7604.0
AKT3	7612.0
NOXO1	7638.0
GNB3	7674.0
RIPK1	7713.0
VPS37B	7718.0
SH3GL1	7772.0
TUBB6	7778.0
SERPINE1	7837.0
MBD3	7891.0
GPC1	7903.0
MAPK8	7911.0
RB1	7933.0
PARP6	7951.0
AKT1	7961.0
PSMA8	8011.0
SDC4	8021.0
ST6GAL1	8043.0
CTSL	8050.0
STX1B	8110.0
MAN2A1	8207.0
ANTXR2	8217.0
ATP1A4	8232.0
CEBPD	8238.0
PSMD14	8243.0
ANO10	8254.0
CPSF4	8260.0
PARP16	8271.0
CUL5	8279.0
GEMIN4	8340.0
ELOA2	8377.0
CYSLTR2	8389.0
PRKACG	8490.0
TUBA8	8510.0
IKBKE	8511.0
CHUK	8515.0
GNAZ	8614.0
C3	8652.0
RNF213	8660.0
AP2A2	8716.0
ERCC3	8718.0
CHD3	8734.0
MAP2K2	8844.0
MVB12B	8883.0
H4C13	8916.0
FCGR2A	8934.0
AP1B1	9014.0
DYNC1H1	9059.0
IFNA5	9072.0
AP1M1	9075.0
NCOR2	9123.0
TAB1	9164.0
TAF2	9219.0
DPEP1	9264.0
IL17RA	9277.0
PRKAR1B	9290.0
MGAT4B	9361.0
PSMD8	9422.0
NUP210	9431.0
TUBA3C	9441.0
SYT2	9447.0
CHMP2B	9475.0
IL17F	9489.0
HGS	9505.0
MTA1	9526.0
AP2M1	9541.0
ADCY3	9562.0
DYNC1LI2	9584.0
CUL3	9592.0
NELFA	9821.0
CTDP1	9874.0
PSMD2	9891.0
RPL3L	9915.0
IFNA6	9953.0
ADCY4	9971.0
FXYD2	10020.0
NOD2	10035.0
RPL10L	10108.0
ATP1A2	10206.0
BRD4	10282.0
TUBB1	10462.0
APOBEC3G	10466.0
FCGR3A	10594.0
PSMB11	10612.0
DVL3	10632.0
GNGT1	10668.0
IFNA14	10963.0
SFTPD	10978.0
MBL2	11015.0

---

REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S

REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S

	1150
set	REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S
setSize	53
pANOVA	4.23e-08
s.dist	-0.435
p.adjustANOVA	2.9e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
EIF3G	-10319
RPS6	-9806
RPS28	-9678
RPS18	-9512
RPS26	-9490
RPS16	-9467
RPS14	-9401
EIF3F	-9276
RPS10	-9091
RPS3A	-8975
RPS3	-8834
RPSA	-8467
EIF3J	-8418
EIF2S1	-8073
RPS9	-7845
RPS19	-7779
RPS2	-7738
RPS8	-7382
RPS7	-7130
RPS15A	-7015

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
EIF3G	-10319
RPS6	-9806
RPS28	-9678
RPS18	-9512
RPS26	-9490
RPS16	-9467
RPS14	-9401
EIF3F	-9276
RPS10	-9091
RPS3A	-8975
RPS3	-8834
RPSA	-8467
EIF3J	-8418
EIF2S1	-8073
RPS9	-7845
RPS19	-7779
RPS2	-7738
RPS8	-7382
RPS7	-7130
RPS15A	-7015
RPS29	-6975
EIF3I	-6950
EIF2S2	-6392
RPS13	-6339
EIF3L	-6206
RPS27L	-6200
RPS11	-5850
EIF4H	-5819
EIF4E	-5369
RPS27	-5318
EIF4A1	-5317
FAU	-5092
EIF4EBP1	-5052
EIF3B	-4157
EIF4A2	-3743
EIF3E	-3449
RPS5	-3417
EIF4B	-3079
RPS12	-2751
RPS27A	-2707
RPS21	-2596
EIF3M	-1602
EIF3D	-955
RPS24	-456
RPS15	320
EIF3K	546
RPS20	828
EIF4G1	4214
RPS25	4809
EIF3H	5737
EIF3A	6273
RPS23	6291
PABPC1	6426

---

REACTOME_DNA_METHYLATION

REACTOME_DNA_METHYLATION

	858
set	REACTOME_DNA_METHYLATION
setSize	58
pANOVA	6.43e-08
s.dist	-0.41
p.adjustANOVA	4.22e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0
H2BC10	-8128.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0
H2BC10	-8128.0
H2AC8	-7580.0
H3C10	-7442.0
H4C6	-7171.0
H2BC11	-6443.0
H3C8	-5893.0
H2AJ	-5812.0
H4C12	-5632.0
H4C2	-5172.0
H2BC15	-5136.0
H4C4	-4850.0
H3C1	-4828.0
H2BC8	-4740.0
H2AX	-4613.0
H4C9	-4394.0
H3C6	-4228.0
H2BC12	-3934.0
H2BC6	-3615.0
H2AC14	-3153.0
H2BC1	-3120.0
UHRF1	-2453.0
H4C16	-2435.0
H3C11	-2128.0
H2BC21	-1800.0
H3-3A	-1031.0
H3-3B	-813.0
H2AC20	-444.0
H4C1	-204.0
H2BC4	586.0
H2BC26	1116.0
DNMT3B	1176.0
DNMT3L	3346.0
H2AC6	3867.0
H2AZ2	4572.0
DNMT1	5467.0
DNMT3A	6119.0
H3C12	6531.0
H3C2	7476.0
H4C13	8916.0

---

REACTOME_SIGNALING_BY_ROBO_RECEPTORS

REACTOME_SIGNALING_BY_ROBO_RECEPTORS

	605
set	REACTOME_SIGNALING_BY_ROBO_RECEPTORS
setSize	206
pANOVA	7.05e-08
s.dist	-0.218
p.adjustANOVA	4.45e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL39L	-10291
RBM8A	-10237
PFN1	-10107
RPL18	-10087
RPL23	-9997
RPL35A	-9988
RPL38	-9969
RPL11	-9821
RPS6	-9806
RPS28	-9678
RPL27A	-9667
RPL34	-9611
RPL26	-9600
RPL28	-9548
PSMD13	-9525
RPS18	-9512
RPS26	-9490
RPS16	-9467
RPL3	-9459
RPS14	-9401

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL39L	-10291.0
RBM8A	-10237.0
PFN1	-10107.0
RPL18	-10087.0
RPL23	-9997.0
RPL35A	-9988.0
RPL38	-9969.0
RPL11	-9821.0
RPS6	-9806.0
RPS28	-9678.0
RPL27A	-9667.0
RPL34	-9611.0
RPL26	-9600.0
RPL28	-9548.0
PSMD13	-9525.0
RPS18	-9512.0
RPS26	-9490.0
RPS16	-9467.0
RPL3	-9459.0
RPS14	-9401.0
PSMB8	-9275.0
RPL9	-9273.0
RPL5	-9093.0
RPS10	-9091.0
PSMA7	-9081.0
RPS3A	-8975.0
RPS3	-8834.0
RPL13	-8701.0
RPLP1	-8700.0
PSMA3	-8660.0
RPL32	-8650.0
RPSA	-8467.0
PSMC5	-8460.0
PSMD4	-8253.0
HOXA2	-8170.0
UBC	-8040.0
RPLP0	-7893.0
RPS9	-7845.0
RPL17	-7840.0
RPS19	-7779.0
RPS2	-7738.0
RPL4	-7711.0
PSMB2	-7696.0
RPL36	-7654.0
RPL41	-7424.0
RPS8	-7382.0
RPL15	-7360.0
PSME2	-7342.0
PSMB3	-7156.0
PSMA4	-7153.0
RPS7	-7130.0
PSMD7	-7104.0
CAP1	-7080.0
RPL37A	-7049.0
RPS15A	-7015.0
RPS29	-6975.0
RPL7A	-6925.0
ENAH	-6920.0
RPL18A	-6838.0
RPL37	-6792.0
PSMB9	-6737.0
PSMC4	-6700.0
NELL2	-6670.0
PSMA5	-6442.0
RPL8	-6347.0
RPS13	-6339.0
PSMD11	-6284.0
RPS27L	-6200.0
PAK2	-6147.0
RPL35	-6032.0
RPL23A	-6024.0
RPL27	-5884.0
RPS11	-5850.0
DCC	-5827.0
RPL29	-5778.0
PSME3	-5547.0
ROBO1	-5453.0
RPL22L1	-5348.0
RPS27	-5318.0
LDB1	-5289.0
RPL12	-5128.0
CDC42	-5100.0
FAU	-5092.0
UBB	-5059.0
PPP3CB	-5002.0
UBA52	-4934.0
ETF1	-4857.0
PSMB10	-4811.0
PSMA6	-4676.0
UPF2	-4474.0
RPL7	-4473.0
PSMD9	-4450.0
RPL26L1	-4159.0
RPL13A	-4097.5
CXCR4	-4018.0
PSMD5	-3781.0
PSMC2	-3476.0
PSMA2	-3445.0
RPS5	-3417.0
PSMD6	-3380.0
PSMB4	-3285.0
MAGOHB	-3262.0
RBX1	-3208.0
PSMC3	-3081.0
ISL1	-2988.0
RPL36AL	-2981.5
SLIT3	-2960.0
RPL14	-2908.0
RPS12	-2751.0
RHOA	-2716.0
RPS27A	-2707.0
RPS21	-2596.0
LHX9	-2533.0
PFN2	-2227.0
ROBO2	-2178.0
USP33	-2101.0
PSMB6	-1764.0
RPL10A	-1720.0
PAK1	-1718.0
PRKCA	-1685.0
NCK2	-1607.0
RPL24	-1557.0
MSI1	-1508.0
CAP2	-1305.0
PAK5	-1271.0
UPF3A	-1262.0
NCK1	-1111.0
PSMC6	-1062.0
RPL30	-893.0
FLRT3	-491.0
RPS24	-456.0
RPL6	-400.0
NTN1	-383.0
SEM1	-38.0
PSMB1	-28.0
PSMA1	296.0
RPS15	320.0
RPS20	828.0
CLASP2	930.0
PRKACB	1045.0
PRKAR2A	1057.0
NCBP1	1140.0
ROBO3	1249.0
ABL1	1449.0
PSMB7	1455.0
ELOC	1468.0
PSME4	1583.0
PSMB5	1628.0
SLIT2	1798.0
NRP1	1855.0
LHX2	1920.0
SRGAP1	1935.5
PRKACA	2053.0
SLIT1	2136.0
LHX4	2151.0
RPL21	2253.0
CLASP1	2683.0
NCBP2	2717.0
MAGOH	3043.0
RPLP2	3532.0
RPL31	3600.0
CXCL12	3839.0
SRGAP3	3857.0
ARHGAP39	3917.0
ABL2	3944.0
VASP	4114.0
SRC	4122.0
CASC3	4135.0
LHX3	4164.0
EIF4G1	4214.0
SOS2	4228.0
PSMD3	4235.0
PSMC1	4252.0
CUL2	4451.0
RNPS1	4625.0
RPL19	4741.0
SOS1	4758.0
RPS25	4809.0
PSMD1	5004.0
MYO9B	5078.0
ELOB	5112.0
PSMF1	5263.0
PAK6	5468.0
RPL22	5772.0
EVL	6131.0
RPS23	6291.0
RAC1	6313.0
PABPC1	6426.0
PSMD12	6808.0
PSME1	7056.0
EIF4A3	7144.0
SRGAP2	7335.0
GSPT1	7518.0
GPC1	7903.0
PSMA8	8011.0
PSMD14	8243.0
AKAP5	8365.0
PRKACG	8490.0
DAG1	8601.0
PAK4	9136.0
PSMD8	9422.0
ZSWIM8	9838.0
PSMD2	9891.0
RPL3L	9915.0
RPL10L	10108.0
PSMB11	10612.0

---

REACTOME_SENESCENCE_ASSOCIATED_SECRETORY_PHENOTYPE_SASP

REACTOME_SENESCENCE_ASSOCIATED_SECRETORY_PHENOTYPE_SASP

	502
set	REACTOME_SENESCENCE_ASSOCIATED_SECRETORY_PHENOTYPE_SASP
setSize	104
pANOVA	7.62e-08
s.dist	-0.305
p.adjustANOVA	4.63e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
IL6	-9934.0
H2BC9	-9924.5
H3C7	-9924.5
UBE2S	-9874.0
CDK4	-9831.0
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
IL1A	-8881.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
IL6	-9934.0
H2BC9	-9924.5
H3C7	-9924.5
UBE2S	-9874.0
CDK4	-9831.0
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
IL1A	-8881.0
CEBPB	-8501.0
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0
H2BC10	-8128.0
UBC	-8040.0
H2AC8	-7580.0
H3C10	-7442.0
CDKN2C	-7371.0
H4C6	-7171.0
CDC16	-7166.0
CDC26	-6803.0
CDKN2D	-6581.0
H2BC11	-6443.0
ANAPC1	-6309.0
FOS	-6098.0
JUN	-5900.0
H3C8	-5893.0
H2AJ	-5812.0
H4C12	-5632.0
H4C2	-5172.0
H2BC15	-5136.0
UBB	-5059.0
UBA52	-4934.0
CDKN2A	-4928.0
H4C4	-4850.0
H3C1	-4828.0
H2BC8	-4740.0
H2AX	-4613.0
CDKN2B	-4480.0
H4C9	-4394.0
H3C6	-4228.0
H2BC12	-3934.0
ANAPC5	-3877.0
UBE2E1	-3620.0
H2BC6	-3615.0
ANAPC10	-3390.0
CDKN1B	-3253.0
H2AC14	-3153.0
H2BC1	-3120.0
MAPK7	-2978.0
IGFBP7	-2842.0
RPS27A	-2707.0
CDK6	-2634.0
H4C16	-2435.0
ANAPC16	-2166.0
H3C11	-2128.0
CCNA2	-1962.0
H2BC21	-1800.0
NFKB1	-1523.0
ANAPC11	-1511.0
CDK2	-1214.0
H3-3A	-1031.0
RELA	-982.0
H3-3B	-813.0
CCNA1	-706.0
H2AC20	-444.0
H4C1	-204.0
CDKN1A	-65.0
H2BC4	586.0
MAPK1	981.0
CDC27	1034.0
H2BC26	1116.0
ANAPC15	1129.0
RPS6KA1	2303.0
ANAPC7	3281.0
CDC23	3434.0
H2AC6	3867.0
RPS6KA2	3972.0
STAT3	4311.0
H2AZ2	4572.0
MAPK3	5125.0
EHMT1	5378.0
UBE2C	5682.0
UBE2D1	6348.0
CXCL8	6479.0
H3C12	6531.0
H3C2	7476.0
EHMT2	7491.0
ANAPC4	7971.0
FZR1	8219.0
H4C13	8916.0
VENTX	9003.0
ANAPC2	9292.0

---

REACTOME_PRC2_METHYLATES_HISTONES_AND_DNA

REACTOME_PRC2_METHYLATES_HISTONES_AND_DNA

	440
set	REACTOME_PRC2_METHYLATES_HISTONES_AND_DNA
setSize	65
pANOVA	9.02e-08
s.dist	-0.383
p.adjustANOVA	5.15e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0
H2BC10	-8128.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0
H2BC10	-8128.0
H2AC8	-7580.0
AEBP2	-7517.0
H3C10	-7442.0
H4C6	-7171.0
H2BC11	-6443.0
H3C8	-5893.0
H2AJ	-5812.0
H4C12	-5632.0
H4C2	-5172.0
H2BC15	-5136.0
H4C4	-4850.0
H3C1	-4828.0
EED	-4751.0
H2BC8	-4740.0
H2AX	-4613.0
H4C9	-4394.0
H3C6	-4228.0
H2BC12	-3934.0
SUZ12	-3901.0
PHF1	-3724.0
H2BC6	-3615.0
H2AC14	-3153.0
H2BC1	-3120.0
RBBP4	-2675.0
H4C16	-2435.0
H3C11	-2128.0
H2BC21	-1800.0
H3-3A	-1031.0
H3-3B	-813.0
H2AC20	-444.0
H4C1	-204.0
H2BC4	586.0
H2BC26	1116.0
DNMT3B	1176.0
JARID2	1891.0
EZH2	2131.0
H2AC6	3867.0
PHF19	4175.0
MTF2	4313.0
H2AZ2	4572.0
DNMT1	5467.0
DNMT3A	6119.0
H3C12	6531.0
H3C2	7476.0
H4C13	8916.0

---

REACTOME_MITOCHONDRIAL_TRANSLATION

REACTOME_MITOCHONDRIAL_TRANSLATION

	874
set	REACTOME_MITOCHONDRIAL_TRANSLATION
setSize	93
pANOVA	9.1e-08
s.dist	-0.321
p.adjustANOVA	5.15e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TUFM	-9885
MRPS11	-9876
MRPL17	-9794
MRPL4	-9305
MRPS18A	-9260
MRPL51	-9233
MRPL53	-9185
MRPL37	-9150
MRPL13	-9145
MRPL32	-8923
MRPL2	-8848
MRPL46	-8605
MTFMT	-8556
MRPS31	-8507
MRPL15	-8425
MRPL58	-8421
MRPS15	-8403
MRPS7	-8395
MRPL48	-8207
MRPL10	-8177

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TUFM	-9885
MRPS11	-9876
MRPL17	-9794
MRPL4	-9305
MRPS18A	-9260
MRPL51	-9233
MRPL53	-9185
MRPL37	-9150
MRPL13	-9145
MRPL32	-8923
MRPL2	-8848
MRPL46	-8605
MTFMT	-8556
MRPS31	-8507
MRPL15	-8425
MRPL58	-8421
MRPS15	-8403
MRPS7	-8395
MRPL48	-8207
MRPL10	-8177
MRPS16	-8029
MRPL21	-8010
MRPL18	-7989
MRPL12	-7921
MRPL33	-7871
MTIF3	-7770
MRPL55	-7722
MRPL40	-7710
MRPL36	-7524
CHCHD1	-7089
MRPS23	-6927
MRPS33	-6892
MRPL39	-6867
MRPL54	-6824
MRPS17	-6822
MRPL41	-6677
TSFM	-6642
MRPL14	-6344
MRPS30	-5841
MRPL27	-5785
MRPL30	-5623
MRPL47	-5312
MRPL3	-5232
MRPL52	-5167
ERAL1	-5119
AURKAIP1	-5110
MRPL9	-5079
MRPL34	-4978
MRPL49	-4933
MRPL24	-4927
MRPS24	-4891
MRPL50	-4848
MRPS12	-4463
MTIF2	-4460
GADD45GIP1	-4001
MRPS18B	-3165
MRPL11	-2897
MRPS10	-2313
MRPS26	-2275
MRPL42	-2238
OXA1L	-2063
GFM2	-2013
MRPS18C	-1832
MRPL57	-1219
DAP3	-1107
MRPS21	-1038
MRPL20	-903
MRPL1	-656
MRPL35	-145
MRPL43	289
MRPS5	771
MRPL44	1296
MRRF	1981
MRPS14	2184
MRPS9	2503
PTCD3	2740
MRPL19	2954
MRPL28	3045
MRPS25	3101
GFM1	3305
MRPS35	3398
MRPS34	3844
MRPS27	4220
MRPS2	4740
MRPS28	5122
MRPL16	5883
MRPS22	5940
MTRF1L	6007
MRPL22	7020
MRPL38	8501
MRPS6	8821
MRPL23	10125
MRPL45	11070

---

REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY

REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY

	1591
set	REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY
setSize	33
pANOVA	1.01e-07
s.dist	-0.535
p.adjustANOVA	5.53e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS6	-9806
RPS28	-9678
HNRNPA1	-9569
RPS18	-9512
RPS26	-9490
RPS16	-9467
RPS14	-9401
RPS10	-9091
RPS3A	-8975
RPS3	-8834
RPSA	-8467
RPS9	-7845
RPS19	-7779
RPS2	-7738
RPS8	-7382
RPS7	-7130
RPS15A	-7015
RPS29	-6975
RPS13	-6339
RPS27L	-6200

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS6	-9806
RPS28	-9678
HNRNPA1	-9569
RPS18	-9512
RPS26	-9490
RPS16	-9467
RPS14	-9401
RPS10	-9091
RPS3A	-8975
RPS3	-8834
RPSA	-8467
RPS9	-7845
RPS19	-7779
RPS2	-7738
RPS8	-7382
RPS7	-7130
RPS15A	-7015
RPS29	-6975
RPS13	-6339
RPS27L	-6200
EEF1A1	-5856
RPS11	-5850
RPS27	-5318
FAU	-5092
RPS5	-3417
RPS12	-2751
RPS27A	-2707
RPS21	-2596
RPS24	-456
RPS15	320
RPS20	828
RPS25	4809
RPS23	6291

---

REACTOME_POSITIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION

REACTOME_POSITIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION

	851
set	REACTOME_POSITIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION
setSize	98
pANOVA	1.1e-07
s.dist	-0.31
p.adjustANOVA	5.82e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
POLR1E	-10495.0
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
TBP	-9553.0
H2AC4	-9538.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
ACTB	-8412.0
H4C5	-8410.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
POLR1E	-10495.0
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
TBP	-9553.0
H2AC4	-9538.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
ACTB	-8412.0
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0
POLR1H	-8215.0
H2BC10	-8128.0
H2AC8	-7580.0
POLR2E	-7485.0
H3C10	-7442.0
DDX21	-7212.0
TAF1D	-7196.0
H4C6	-7171.0
GSK3B	-6981.0
GATAD2B	-6523.0
H2BC11	-6443.0
POLR1C	-6163.0
H3C8	-5893.0
POLR1G	-5845.0
H2AJ	-5812.0
KAT2B	-5664.0
H4C12	-5632.0
H4C2	-5172.0
H2BC15	-5136.0
H4C4	-4850.0
H3C1	-4828.0
SMARCA5	-4808.0
H2BC8	-4740.0
POLR1F	-4737.0
BAZ1B	-4618.0
H2AX	-4613.0
POLR1B	-4549.0
EP300	-4543.0
H4C9	-4394.0
H3C6	-4228.0
H2BC12	-3934.0
POLR2F	-3657.0
H2BC6	-3615.0
H2AC14	-3153.0
H2BC1	-3120.0
POLR2H	-2710.0
RBBP4	-2675.0
CBX3	-2592.0
H4C16	-2435.0
H3C11	-2128.0
TTF1	-2113.0
TAF1B	-1985.0
H2BC21	-1800.0
SF3B1	-1499.0
POLR1D	-1301.0
H3-3A	-1031.0
H3-3B	-813.0
POLR2K	-624.0
H2AC20	-444.0
POLR2L	-372.0
H4C1	-204.0
KAT2A	-148.0
HDAC1	78.0
MTA3	331.0
MYO1C	544.0
H2BC4	586.0
H2BC26	1116.0
POLR1A	2501.0
HDAC2	2992.0
MTA2	3356.0
ERCC6	3768.0
H2AC6	3867.0
DEK	3890.0
H2AZ2	4572.0
TAF1A	4620.0
GATAD2A	5020.0
CHD4	5360.0
H3C12	6531.0
MYBBP1A	6607.0
H3C2	7476.0
EHMT2	7491.0
MBD3	7891.0
TAF1C	8532.0
CHD3	8734.0
H4C13	8916.0
MTA1	9526.0

---

REACTOME_DNA_REPLICATION

REACTOME_DNA_REPLICATION

	1113
set	REACTOME_DNA_REPLICATION
setSize	178
pANOVA	1.31e-07
s.dist	-0.229
p.adjustANOVA	6.73e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
POLE3	-10268.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
MCM5	-9967.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
UBE2S	-9874.0
H4C11	-9725.0
POLE4	-9697.0
H2BC5	-9558.0
H2AC4	-9538.0
PSMD13	-9525.0
PSMB8	-9275.0
H3C3	-9117.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
POLE3	-10268.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
MCM5	-9967.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
UBE2S	-9874.0
H4C11	-9725.0
POLE4	-9697.0
H2BC5	-9558.0
H2AC4	-9538.0
PSMD13	-9525.0
PSMB8	-9275.0
H3C3	-9117.0
PSMA7	-9081.0
H2AC7	-8983.5
H2BC7	-8983.5
POLD4	-8861.0
PSMA3	-8660.0
RFC4	-8512.0
PSMC5	-8460.0
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0
PSMD4	-8253.0
H2BC10	-8128.0
UBC	-8040.0
FEN1	-7941.0
PSMB2	-7696.0
H2AC8	-7580.0
KPNB1	-7455.0
H3C10	-7442.0
PSME2	-7342.0
H4C6	-7171.0
CDC16	-7166.0
PSMB3	-7156.0
PSMA4	-7153.0
DBF4	-7142.0
PSMD7	-7104.0
SKP1	-7085.0
CDC26	-6803.0
PSMB9	-6737.0
PSMC4	-6700.0
H2BC11	-6443.0
PSMA5	-6442.0
MCM8	-6337.0
ANAPC1	-6309.0
PSMD11	-6284.0
RPA2	-6177.0
POLA2	-5905.0
H3C8	-5893.0
H2AJ	-5812.0
GINS2	-5806.0
H4C12	-5632.0
PSME3	-5547.0
KPNA1	-5353.0
H4C2	-5172.0
H2BC15	-5136.0
UBB	-5059.0
UBA52	-4934.0
H4C4	-4850.0
H3C1	-4828.0
PSMB10	-4811.0
H2BC8	-4740.0
MCM6	-4722.0
PSMA6	-4676.0
H2AX	-4613.0
PRIM2	-4490.0
PSMD9	-4450.0
H4C9	-4394.0
H3C6	-4228.0
ORC1	-4115.0
ORC2	-3938.0
H2BC12	-3934.0
ANAPC5	-3877.0
PSMD5	-3781.0
UBE2E1	-3620.0
H2BC6	-3615.0
PSMC2	-3476.0
PSMA2	-3445.0
MCM4	-3404.0
ANAPC10	-3390.0
PSMD6	-3380.0
PSMB4	-3285.0
RBX1	-3208.0
H2AC14	-3153.0
MCM10	-3137.0
H2BC1	-3120.0
PSMC3	-3081.0
RPS27A	-2707.0
H4C16	-2435.0
CCNE1	-2408.0
PCNA	-2279.0
ANAPC16	-2166.0
CDC6	-2152.0
H3C11	-2128.0
CCNA2	-1962.0
H2BC21	-1800.0
PSMB6	-1764.0
ORC3	-1754.0
ANAPC11	-1511.0
CDK2	-1214.0
RFC3	-1186.0
PRIM1	-1066.0
PSMC6	-1062.0
H3-3A	-1031.0
H3-3B	-813.0
CCNA1	-706.0
H2AC20	-444.0
RFC2	-242.0
SKP2	-213.0
H4C1	-204.0
SEM1	-38.0
PSMB1	-28.0
PSMA1	296.0
MCM3	342.0
GINS1	367.0
POLD3	566.0
H2BC4	586.0
ORC5	821.0
GINS4	911.0
CDC27	1034.0
CDC7	1087.0
H2BC26	1116.0
ANAPC15	1129.0
PSMB7	1455.0
RFC5	1528.0
PSME4	1583.0
CDT1	1607.0
PSMB5	1628.0
GMNN	1922.0
DNA2	2097.0
RPA3	2233.0
POLD1	2458.0
ORC4	2489.0
CCNE2	2538.0
CUL1	3151.0
MCM7	3207.0
RFC1	3235.0
ANAPC7	3281.0
CDC23	3434.0
RPA1	3825.0
POLD2	3854.0
H2AC6	3867.0
PSMD3	4235.0
PSMC1	4252.0
KPNA6	4371.0
H2AZ2	4572.0
PSMD1	5004.0
PSMF1	5263.0
LIG1	5490.0
UBE2C	5682.0
UBE2D1	6348.0
POLE2	6363.0
ORC6	6395.0
H3C12	6531.0
PSMD12	6808.0
GINS3	6883.0
CDC45	7024.0
PSME1	7056.0
H3C2	7476.0
ANAPC4	7971.0
PSMA8	8011.0
FZR1	8219.0
PSMD14	8243.0
POLE	8419.0
H4C13	8916.0
ANAPC2	9292.0
PSMD8	9422.0
MCM2	9504.0
PSMD2	9891.0
PSMB11	10612.0

---

REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE

REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE

	1025
set	REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE
setSize	66
pANOVA	2.7e-07
s.dist	-0.366
p.adjustANOVA	1.34e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
CENPM	-10175.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
H2AC7	-8983.5
H2BC7	-8983.5
H4C5	-8410.0
H2AZ1	-8280.0
H2BC10	-8128.0
CENPL	-7786.0
H2AC8	-7580.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
CENPM	-10175.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
H2AC7	-8983.5
H2BC7	-8983.5
H4C5	-8410.0
H2AZ1	-8280.0
H2BC10	-8128.0
CENPL	-7786.0
H2AC8	-7580.0
CENPC	-7482.0
NPM1	-7384.0
KNL1	-7176.0
H4C6	-7171.0
H2BC11	-6443.0
OIP5	-6295.0
MIS18BP1	-6271.0
H2AJ	-5812.0
H4C12	-5632.0
H4C2	-5172.0
H2BC15	-5136.0
H4C4	-4850.0
SMARCA5	-4808.0
H2BC8	-4740.0
H2AX	-4613.0
ITGB3BP	-4411.0
H4C9	-4394.0
CENPH	-4309.0
H2BC12	-3934.0
CENPT	-3866.0
CENPW	-3713.0
H2BC6	-3615.0
H2AC14	-3153.0
H2BC1	-3120.0
RBBP4	-2675.0
H4C16	-2435.0
H2BC21	-1800.0
RUVBL1	-1335.0
H2AC20	-444.0
H4C1	-204.0
CENPK	22.0
H2BC4	586.0
CENPQ	740.0
H2BC26	1116.0
RSF1	1281.0
CENPA	3182.0
CENPN	3387.0
H2AC6	3867.0
H2AZ2	4572.0
MIS18A	4672.0
CENPO	5812.0
CENPP	6008.0
CENPU	7052.0
CENPS	7311.0
H4C13	8916.0
HJURP	9611.0

---

REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS

REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS

	901
set	REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS
setSize	113
pANOVA	3e-07
s.dist	-0.279
p.adjustANOVA	1.45e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
POLR2J	-10179.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
PAGR1	-9886.0
POLR2I	-9848.0
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
HOXA1	-9536.0
CTCF	-9414.0
NCOA6	-9190.0
H3C3	-9117.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
POLR2J	-10179.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
PAGR1	-9886.0
POLR2I	-9848.0
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
HOXA1	-9536.0
CTCF	-9414.0
NCOA6	-9190.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
ZNF335	-8906.0
H4C5	-8410.0
H3C4	-8401.0
HOXB4	-8325.0
H2AZ1	-8280.0
MAFB	-8249.0
HOXA2	-8170.0
H2BC10	-8128.0
RARG	-7735.0
H2AC8	-7580.0
POLR2E	-7485.0
H3C10	-7442.0
H4C6	-7171.0
HOXC4	-6828.0
PAX6	-6801.0
H2BC11	-6443.0
AJUBA	-6355.0
HOXA3	-6044.0
JUN	-5900.0
H3C8	-5893.0
H2AJ	-5812.0
H4C12	-5632.0
CNOT9	-5320.0
EGR2	-5176.0
H4C2	-5172.0
H2BC15	-5136.0
H4C4	-4850.0
H3C1	-4828.0
EED	-4751.0
H2BC8	-4740.0
POLR2C	-4652.0
H2AX	-4613.0
EP300	-4543.0
H4C9	-4394.0
RBBP5	-4288.0
H3C6	-4228.0
H2BC12	-3934.0
SUZ12	-3901.0
POLR2F	-3657.0
H2BC6	-3615.0
PAXIP1	-3505.0
H2AC14	-3153.0
H2BC1	-3120.0
POLR2H	-2710.0
RBBP4	-2675.0
H4C16	-2435.0
H3C11	-2128.0
H2BC21	-1800.0
HOXD3	-1681.0
POLR2G	-1573.0
HOXD4	-1350.0
PCGF2	-1176.0
H3-3A	-1031.0
HOXB2	-1010.0
H3-3B	-813.0
POLR2K	-624.0
NCOR1	-527.0
NCOA3	-476.0
H2AC20	-444.0
POLR2L	-372.0
H4C1	-204.0
ASH2L	91.0
H2BC4	586.0
H2BC26	1116.0
RARB	1389.0
PIAS2	1734.0
EZH2	2131.0
YY1	2309.0
HOXD1	2383.0
CNOT6	2866.0
H2AC6	3867.0
H2AZ2	4572.0
CREBBP	4616.0
PBX1	5014.0
POLR2D	5189.0
POLR2B	5721.0
MEIS1	6421.0
H3C12	6531.0
HDAC3	6994.0
POLR2A	7019.0
RARA	7105.0
PKNOX1	7326.0
H3C2	7476.0
HOXB1	7682.0
HOXB3	8116.0
WDR5	8384.0
KMT2C	8551.0
H4C13	8916.0
HOXA4	9819.0
RXRA	10290.0
KMT2D	10859.0

---

REACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

REACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

	887
set	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS
setSize	100
pANOVA	3.74e-07
s.dist	-0.294
p.adjustANOVA	1.75e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
POLR2J	-10179.0
H4C3	-10142.0
SEH1L	-10060.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
POLR2I	-9848.0
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
NUP42	-9274.0
NUP43	-9181.0
H3C3	-9117.0
H2AC7	-8983.5

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
POLR2J	-10179.0
H4C3	-10142.0
SEH1L	-10060.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
POLR2I	-9848.0
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
NUP42	-9274.0
NUP43	-9181.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
NUP107	-8608.0
AGO1	-8521.0
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0
H2BC10	-8128.0
NUP37	-7953.0
NUP160	-7693.0
H2AC8	-7580.0
POLR2E	-7485.0
H3C10	-7442.0
H4C6	-7171.0
NUP50	-6564.0
H2BC11	-6443.0
H3C8	-5893.0
H2AJ	-5812.0
H4C12	-5632.0
H4C2	-5172.0
H2BC15	-5136.0
NUP153	-5033.0
H4C4	-4850.0
H3C1	-4828.0
RAN	-4756.0
H2BC8	-4740.0
POLR2C	-4652.0
H2AX	-4613.0
H4C9	-4394.0
H3C6	-4228.0
H2BC12	-3934.0
IPO8	-3763.0
POLR2F	-3657.0
H2BC6	-3615.0
NUP155	-3436.0
H2AC14	-3153.0
H2BC1	-3120.0
TPR	-2890.0
POLR2H	-2710.0
NUP85	-2443.0
H4C16	-2435.0
H3C11	-2128.0
NUP98	-1888.0
H2BC21	-1800.0
POLR2G	-1573.0
H3-3A	-1031.0
H3-3B	-813.0
POLR2K	-624.0
H2AC20	-444.0
POLR2L	-372.0
NUP58	-237.0
H4C1	-204.0
SEC13	66.0
NUP35	446.0
H2BC4	586.0
H2BC26	1116.0
NUP88	1334.0
NDC1	1422.0
NUP214	1526.0
POM121C	1782.0
NUP188	2308.0
NUP54	2991.0
NUP133	3395.0
NUP62	3527.0
H2AC6	3867.0
RAE1	4292.0
H2AZ2	4572.0
NUP93	4585.0
AAAS	4604.0
POLR2D	5189.0
NUP205	5228.0
POLR2B	5721.0
RANBP2	5895.0
H3C12	6531.0
POLR2A	7019.0
POM121	7060.0
AGO2	7427.0
H3C2	7476.0
TNRC6A	8122.0
H4C13	8916.0
NUP210	9431.0

---

REACTOME_DISEASES_OF_PROGRAMMED_CELL_DEATH

REACTOME_DISEASES_OF_PROGRAMMED_CELL_DEATH

	1502
set	REACTOME_DISEASES_OF_PROGRAMMED_CELL_DEATH
setSize	96
pANOVA	4.09e-07
s.dist	-0.299
p.adjustANOVA	1.87e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
FASLG	-10201.0
PRDX2	-10200.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
SOD2	-9128.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
FADD	-8658.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
FASLG	-10201.0
PRDX2	-10200.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
SOD2	-9128.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
FADD	-8658.0
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0
H2BC10	-8128.0
LMNA	-7958.0
CDK5	-7894.0
YWHAE	-7836.0
H2AC8	-7580.0
TRADD	-7532.0
H3C10	-7442.0
H4C6	-7171.0
H2BC11	-6443.0
POLA2	-5905.0
JUN	-5900.0
H3C8	-5893.0
H2AJ	-5812.0
CAPN1	-5634.0
H4C12	-5632.0
H4C2	-5172.0
H2BC15	-5136.0
CDC25C	-5040.0
CDKN2A	-4928.0
H4C4	-4850.0
H3C1	-4828.0
EED	-4751.0
H2BC8	-4740.0
LMNB1	-4730.0
H2AX	-4613.0
PRIM2	-4490.0
H4C9	-4394.0
CASP8	-4353.0
H3C6	-4228.0
H2BC12	-3934.0
SUZ12	-3901.0
H2BC6	-3615.0
MLKL	-3588.0
H2AC14	-3153.0
H2BC1	-3120.0
RBBP4	-2675.0
H4C16	-2435.0
H3C11	-2128.0
H2BC21	-1800.0
TP53	-1704.0
PRIM1	-1066.0
H3-3A	-1031.0
BCL2L11	-1016.0
H3-3B	-813.0
H2AC20	-444.0
H4C1	-204.0
APP	339.0
H2BC4	586.0
H2BC26	1116.0
DNMT3B	1176.0
EZH2	2131.0
CDC25B	2429.0
CDC25A	2835.0
FOXO3	3234.0
CAST	3328.0
CDK5R1	3376.0
C1QBP	3637.0
CAPNS2	3668.0
H2AC6	3867.0
H2AZ2	4572.0
DNMT1	5467.0
TRAF2	5475.0
DNMT3A	6119.0
RIPK3	6287.0
H3C12	6531.0
PRDX1	7142.0
CAPN2	7392.0
H3C2	7476.0
RIPK1	7713.0
GOLGA2	7879.0
GSDME	8115.0
CAPNS1	8177.0
H4C13	8916.0

---

REACTOME_INHIBITION_OF_DNA_RECOMBINATION_AT_TELOMERE

REACTOME_INHIBITION_OF_DNA_RECOMBINATION_AT_TELOMERE

	1530
set	REACTOME_INHIBITION_OF_DNA_RECOMBINATION_AT_TELOMERE
setSize	63
pANOVA	4.98e-07
s.dist	-0.366
p.adjustANOVA	2.21e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
POLR2J	-10179.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
POLR2I	-9848.0
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
H2AC7	-8983.5
H2BC7	-8983.5
H4C5	-8410.0
H2AZ1	-8280.0
H2BC10	-8128.0
TERF2IP	-8102.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
POLR2J	-10179.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
POLR2I	-9848.0
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
H2AC7	-8983.5
H2BC7	-8983.5
H4C5	-8410.0
H2AZ1	-8280.0
H2BC10	-8128.0
TERF2IP	-8102.0
H2AC8	-7580.0
POLR2E	-7485.0
H4C6	-7171.0
TERF1	-6818.0
H2BC11	-6443.0
H2AJ	-5812.0
H4C12	-5632.0
H4C2	-5172.0
H2BC15	-5136.0
TINF2	-4952.0
H4C4	-4850.0
H2BC8	-4740.0
POLR2C	-4652.0
H2AX	-4613.0
H4C9	-4394.0
H2BC12	-3934.0
POLR2F	-3657.0
H2BC6	-3615.0
H2AC14	-3153.0
H2BC1	-3120.0
POLR2H	-2710.0
H4C16	-2435.0
H2BC21	-1800.0
POLR2G	-1573.0
H3-3A	-1031.0
H3-3B	-813.0
POLR2K	-624.0
H2AC20	-444.0
POLR2L	-372.0
H4C1	-204.0
H2BC4	586.0
H2BC26	1116.0
DAXX	3128.0
H2AC6	3867.0
H2AZ2	4572.0
TERF2	5034.0
POLR2D	5189.0
ACD	5204.5
POLR2B	5721.0
POT1	6490.0
POLR2A	7019.0
H3-4	7838.0
H4C13	8916.0

---

REACTOME_CONDENSATION_OF_PROPHASE_CHROMOSOMES

REACTOME_CONDENSATION_OF_PROPHASE_CHROMOSOMES

	480
set	REACTOME_CONDENSATION_OF_PROPHASE_CHROMOSOMES
setSize	66
pANOVA	6.18e-07
s.dist	-0.355
p.adjustANOVA	2.67e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
SMC4	-10205.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
SMC4	-10205.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0
CDK1	-8136.0
H2BC10	-8128.0
H2AC8	-7580.0
SMC2	-7515.0
H3C10	-7442.0
H4C6	-7171.0
H2BC11	-6443.0
H3C8	-5893.0
H2AJ	-5812.0
H4C12	-5632.0
H4C2	-5172.0
H2BC15	-5136.0
SET	-5132.0
H4C4	-4850.0
H3C1	-4828.0
H2BC8	-4740.0
H2AX	-4613.0
H4C9	-4394.0
H3C6	-4228.0
H2BC12	-3934.0
H2BC6	-3615.0
H2AC14	-3153.0
H2BC1	-3120.0
H4C16	-2435.0
H3C11	-2128.0
H2BC21	-1800.0
H3-3A	-1031.0
H3-3B	-813.0
NCAPH2	-453.0
H2AC20	-444.0
NCAPG2	-304.0
H4C1	-204.0
H2BC4	586.0
H2BC26	1116.0
H2AC6	3867.0
CCNB1	4504.0
H2AZ2	4572.0
PLK1	6277.0
H3C12	6531.0
H3C2	7476.0
NCAPD3	7748.0
H3-4	7838.0
RB1	7933.0
KMT5A	8179.0
MCPH1	8586.0
H4C13	8916.0

---

REACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS

REACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS

	1476
set	REACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS
setSize	83
pANOVA	7.01e-07
s.dist	-0.315
p.adjustANOVA	2.91e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
CDK4	-9831.0
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
MYC	-8846.0
CEBPB	-8501.0
H4C5	-8410.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
CDK4	-9831.0
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
MYC	-8846.0
CEBPB	-8501.0
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0
H2BC10	-8128.0
LEF1	-8061.0
GFI1	-7657.0
H2AC8	-7580.0
H3C10	-7442.0
H4C6	-7171.0
H2BC11	-6443.0
E2F1	-6323.0
H3C8	-5893.0
H2AJ	-5812.0
H4C12	-5632.0
GATA2	-5361.0
CBFB	-5323.0
H4C2	-5172.0
H2BC15	-5136.0
H4C4	-4850.0
H3C1	-4828.0
H2BC8	-4740.0
H2AX	-4613.0
EP300	-4543.0
TAL1	-4419.0
H4C9	-4394.0
H3C6	-4228.0
TFDP2	-4086.0
H2BC12	-3934.0
H2BC6	-3615.0
KMT2A	-3359.0
H2AC14	-3153.0
H2BC1	-3120.0
H4C16	-2435.0
H3C11	-2128.0
RUNX1	-1819.0
H2BC21	-1800.0
MYB	-1291.0
CDK2	-1214.0
H3-3A	-1031.0
H3-3B	-813.0
H2AC20	-444.0
H4C1	-204.0
CDKN1A	-65.0
IL6R	18.0
PML	514.0
H2BC4	586.0
H2BC26	1116.0
KLF5	2251.0
SPI1	3035.0
H2AC6	3867.0
DEK	3890.0
STAT3	4311.0
CEBPA	4507.0
H2AZ2	4572.0
CSF3R	5574.0
FLI1	6000.0
CREB1	6384.0
H3C12	6531.0
RARA	7105.0
H3C2	7476.0
H4C13	8916.0
TFDP1	9663.0
CEBPE	9714.0
RXRA	10290.0

---

REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION

REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION

	1163
set	REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION
setSize	102
pANOVA	7.09e-07
s.dist	-0.284
p.adjustANOVA	2.91e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
POLR1E	-10495.0
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
TBP	-9553.0
H2AC4	-9538.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
CAVIN1	-8970.0
H4C5	-8410.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
POLR1E	-10495.0
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
TBP	-9553.0
H2AC4	-9538.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
CAVIN1	-8970.0
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0
POLR1H	-8215.0
H2BC10	-8128.0
H2AC8	-7580.0
POLR2E	-7485.0
H3C10	-7442.0
TAF1D	-7196.0
H4C6	-7171.0
GATAD2B	-6523.0
H2BC11	-6443.0
GTF2H3	-6340.0
POLR1C	-6163.0
H3C8	-5893.0
POLR1G	-5845.0
CDK7	-5825.0
H2AJ	-5812.0
KAT2B	-5664.0
H4C12	-5632.0
MNAT1	-5299.0
H4C2	-5172.0
H2BC15	-5136.0
CCNH	-4866.0
H4C4	-4850.0
H3C1	-4828.0
H2BC8	-4740.0
POLR1F	-4737.0
H2AX	-4613.0
POLR1B	-4549.0
H4C9	-4394.0
H3C6	-4228.0
H2BC12	-3934.0
POLR2F	-3657.0
H2BC6	-3615.0
MBD2	-3520.0
UBTF	-3295.0
H2AC14	-3153.0
H2BC1	-3120.0
GTF2H5	-3090.0
POLR2H	-2710.0
RBBP4	-2675.0
CBX3	-2592.0
H4C16	-2435.0
H3C11	-2128.0
TTF1	-2113.0
TAF1B	-1985.0
H2BC21	-1800.0
POLR1D	-1301.0
H3-3A	-1031.0
H3-3B	-813.0
POLR2K	-624.0
H2AC20	-444.0
POLR2L	-372.0
H4C1	-204.0
KAT2A	-148.0
HDAC1	78.0
MTA3	331.0
H2BC4	586.0
ERCC2	1041.0
H2BC26	1116.0
GTF2H1	2125.0
POLR1A	2501.0
HDAC2	2992.0
MTA2	3356.0
ERCC6	3768.0
H2AC6	3867.0
H2AZ2	4572.0
TAF1A	4620.0
GATAD2A	5020.0
MAPK3	5125.0
CHD4	5360.0
GTF2H4	5742.0
H3C12	6531.0
H3C2	7476.0
EHMT2	7491.0
RRN3	7841.0
MBD3	7891.0
TAF1C	8532.0
ERCC3	8718.0
CHD3	8734.0
H4C13	8916.0
MTA1	9526.0

---

REACTOME_G2_M_CHECKPOINTS

REACTOME_G2_M_CHECKPOINTS

	1116
set	REACTOME_G2_M_CHECKPOINTS
setSize	162
pANOVA	8.94e-07
s.dist	-0.224
p.adjustANOVA	3.58e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SFN	-10645.0
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
MCM5	-9967.0
H2BC13	-9956.0
H2BC9	-9924.5
H4C11	-9725.0
CHEK2	-9618.0
H2BC5	-9558.0
PSMD13	-9525.0
RAD50	-9451.0
PSMB8	-9275.0
RHNO1	-9236.0
PSMA7	-9081.0
RAD17	-9057.0
BRCA1	-9053.0
H2BC7	-8983.5

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SFN	-10645.0
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
MCM5	-9967.0
H2BC13	-9956.0
H2BC9	-9924.5
H4C11	-9725.0
CHEK2	-9618.0
H2BC5	-9558.0
PSMD13	-9525.0
RAD50	-9451.0
PSMB8	-9275.0
RHNO1	-9236.0
PSMA7	-9081.0
RAD17	-9057.0
BRCA1	-9053.0
H2BC7	-8983.5
PSMA3	-8660.0
RFC4	-8512.0
PSMC5	-8460.0
YWHAZ	-8450.0
H4C5	-8410.0
PSMD4	-8253.0
CDK1	-8136.0
H2BC10	-8128.0
UBC	-8040.0
YWHAE	-7836.0
PSMB2	-7696.0
PIAS4	-7486.0
KAT5	-7394.0
PSME2	-7342.0
CLSPN	-7189.0
H4C6	-7171.0
PSMB3	-7156.0
PSMA4	-7153.0
DBF4	-7142.0
PSMD7	-7104.0
PSMB9	-6737.0
PSMC4	-6700.0
H2BC11	-6443.0
PSMA5	-6442.0
MCM8	-6337.0
PSMD11	-6284.0
RPA2	-6177.0
BRIP1	-6042.0
UBE2N	-6001.0
H4C12	-5632.0
PSME3	-5547.0
EXO1	-5529.0
H4C2	-5172.0
H2BC15	-5136.0
HUS1	-5066.0
UBB	-5059.0
CDC25C	-5040.0
UBA52	-4934.0
H4C4	-4850.0
PSMB10	-4811.0
H2BC8	-4740.0
MCM6	-4722.0
CCNB2	-4702.0
PSMA6	-4676.0
H2AX	-4613.0
TP53BP1	-4612.0
RAD1	-4600.0
BABAM1	-4582.0
BARD1	-4515.0
PSMD9	-4450.0
RBBP8	-4437.0
H4C9	-4394.0
ORC1	-4115.0
ORC2	-3938.0
H2BC12	-3934.0
PSMD5	-3781.0
UBE2V2	-3780.0
H2BC6	-3615.0
PSMC2	-3476.0
PSMA2	-3445.0
MCM4	-3404.0
PSMD6	-3380.0
TOPBP1	-3302.0
PSMB4	-3285.0
MCM10	-3137.0
H2BC1	-3120.0
PSMC3	-3081.0
ATM	-2904.0
RPS27A	-2707.0
H4C16	-2435.0
CDC6	-2152.0
RNF8	-2012.0
NBN	-1875.0
H2BC21	-1800.0
PSMB6	-1764.0
ORC3	-1754.0
TP53	-1704.0
CHEK1	-1285.0
RAD9A	-1236.0
CDK2	-1214.0
RFC3	-1186.0
PSMC6	-1062.0
ABRAXAS1	-514.0
RFC2	-242.0
H4C1	-204.0
RAD9B	-147.0
SEM1	-38.0
PSMB1	-28.0
MDC1	120.0
PSMA1	296.0
MCM3	342.0
BLM	541.0
H2BC4	586.0
ORC5	821.0
CDC7	1087.0
RMI1	1112.0
H2BC26	1116.0
YWHAH	1231.0
PSMB7	1455.0
PKMYT1	1472.0
RFC5	1528.0
PSME4	1583.0
PSMB5	1628.0
GTSE1	1641.0
YWHAB	1794.0
DNA2	2097.0
RPA3	2233.0
ORC4	2489.0
YWHAQ	2738.0
CDC25A	2835.0
YWHAG	2854.0
RMI2	2856.0
MCM7	3207.0
ATR	3233.0
RPA1	3825.0
WRN	3949.0
PSMD3	4235.0
PSMC1	4252.0
CCNB1	4504.0
BABAM2	4513.0
UIMC1	4895.0
PSMD1	5004.0
PSMF1	5263.0
WEE1	5813.0
ATRIP	6078.0
TOP3A	6257.0
ORC6	6395.0
MRE11	6746.0
PSMD12	6808.0
CDC45	7024.0
PSME1	7056.0
RNF168	7279.0
NSD2	7557.0
H3-4	7838.0
PSMA8	8011.0
PSMD14	8243.0
H4C13	8916.0
HERC2	9295.0
PSMD8	9422.0
MCM2	9504.0
PSMD2	9891.0
PSMB11	10612.0

---

REACTOME_SARS_COV_2_MODULATES_HOST_TRANSLATION_MACHINERY

REACTOME_SARS_COV_2_MODULATES_HOST_TRANSLATION_MACHINERY

	1601
set	REACTOME_SARS_COV_2_MODULATES_HOST_TRANSLATION_MACHINERY
setSize	46
pANOVA	9.3e-07
s.dist	-0.418
p.adjustANOVA	3.64e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS6	-9806
RPS28	-9678
RPS18	-9512
RPS26	-9490
RPS16	-9467
RPS14	-9401
SNRPD2	-9397
GEMIN5	-9279
RPS10	-9091
RPS3A	-8975
RPS3	-8834
GEMIN2	-8513
DDX20	-8485
RPSA	-8467
RPS9	-7845
RPS19	-7779
RPS2	-7738
RPS8	-7382
RPS7	-7130
RPS15A	-7015

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS6	-9806.0
RPS28	-9678.0
RPS18	-9512.0
RPS26	-9490.0
RPS16	-9467.0
RPS14	-9401.0
SNRPD2	-9397.0
GEMIN5	-9279.0
RPS10	-9091.0
RPS3A	-8975.0
RPS3	-8834.0
GEMIN2	-8513.0
DDX20	-8485.0
RPSA	-8467.0
RPS9	-7845.0
RPS19	-7779.0
RPS2	-7738.0
RPS8	-7382.0
RPS7	-7130.0
RPS15A	-7015.0
RPS29	-6975.0
SNRPG	-6599.0
SNRPD1	-6546.0
RPS13	-6339.0
RPS27L	-6200.0
SNRPD3	-6155.0
RPS11	-5850.0
RPS27	-5318.0
GEMIN6	-5280.0
FAU	-5092.0
RPS5	-3417.0
RPS12	-2751.0
RPS27A	-2707.0
RPS21	-2596.0
SNRPF	-1314.0
RPS24	-456.0
RPS15	320.0
RPS20	828.0
GEMIN7	2106.0
SMN1	4401.5
SMN2	4401.5
RPS25	4809.0
SNRPB	5980.0
SNRPE	6152.0
RPS23	6291.0
GEMIN4	8340.0

---

REACTOME_REPRODUCTION

REACTOME_REPRODUCTION

	114
set	REACTOME_REPRODUCTION
setSize	136
pANOVA	1.12e-06
s.dist	-0.242
p.adjustANOVA	4.23e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
IZUMO3	-10323.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
MSH4	-9933.0
H2BC9	-9924.5
H3C7	-9924.5
CDK4	-9831.0
H4C11	-9725.0
RAD21	-9607.0
H2BC5	-9558.0
H2AC4	-9538.0
RAD50	-9451.0
IZUMO1	-9180.0
H3C3	-9117.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
IZUMO3	-10323.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
MSH4	-9933.0
H2BC9	-9924.5
H3C7	-9924.5
CDK4	-9831.0
H4C11	-9725.0
RAD21	-9607.0
H2BC5	-9558.0
H2AC4	-9538.0
RAD50	-9451.0
IZUMO1	-9180.0
H3C3	-9117.0
BRCA1	-9053.0
H2AC7	-8983.5
H2BC7	-8983.5
SPO11	-8732.0
BRCA2	-8726.0
CATSPERG	-8515.0
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0
H2BC10	-8128.0
TERF2IP	-8102.0
LMNA	-7958.0
H2AC8	-7580.0
H3C10	-7442.0
ZP2	-7341.0
SPAM1	-7236.0
RAD51C	-7228.0
H4C6	-7171.0
TERF1	-6818.0
IZUMO4	-6771.0
FKBP6	-6556.0
H2BC11	-6443.0
STAG3	-6299.0
RPA2	-6177.0
H3C8	-5893.0
HVCN1	-5892.0
KCNU1	-5877.0
H2AJ	-5812.0
CATSPER2	-5722.0
H4C12	-5632.0
ADAM2	-5415.0
H4C2	-5172.0
H2BC15	-5136.0
TINF2	-4952.0
H4C4	-4850.0
ADAM20	-4847.0
H3C1	-4828.0
SMC3	-4817.0
OVGP1	-4744.0
H2BC8	-4740.0
LMNB1	-4730.0
H2AX	-4613.0
RBBP8	-4437.0
H4C9	-4394.0
H3C6	-4228.0
CATSPER1	-4040.0
B4GALT1	-3976.0
H2BC12	-3934.0
H2BC6	-3615.0
RAD51	-3603.0
ADAM30	-3307.0
H2AC14	-3153.0
H2BC1	-3120.0
REC8	-2916.0
ATM	-2904.0
MLH1	-2713.0
H4C16	-2435.0
H3C11	-2128.0
NBN	-1875.0
H2BC21	-1800.0
IZUMO2	-1385.0
SYCE1	-1328.0
CDK2	-1214.0
ZP1	-1146.0
H3-3A	-1031.0
PSMC3IP	-883.0
H3-3B	-813.0
HSPA2	-580.0
H2AC20	-444.0
MND1	-236.0
H4C1	-204.0
MSH5	-9.0
BLM	541.0
DIDO1	572.0
H2BC4	586.0
ZP3	1103.0
H2BC26	1116.0
STAG1	1118.0
TEX15	1381.0
CATSPERD	1499.0
CATSPERB	1687.0
RPA3	2233.0
DMC1	2773.0
ATR	3233.0
SYCE3	3365.0
UBE2I	3611.0
CD9	3663.0
ACR	3824.0
RPA1	3825.0
H2AC6	3867.0
SYNE1	4022.0
SUN2	4284.0
SYCP1	4472.0
ZP4	4540.0
H2AZ2	4572.0
PRDM9	4850.0
TERF2	5034.0
ADAM21	5174.0
ACD	5204.5
TEX12	5566.0
CATSPER4	6180.0
TOP3A	6257.0
POT1	6490.0
H3C12	6531.0
MLH3	6715.0
MRE11	6746.0
H3C2	7476.0
SMC1B	7529.0
SYCE2	7630.0
SYNE2	7719.0
H3-4	7838.0
SYCP2	8299.0
SYCP3	8631.0
SUN1	8762.0
H4C13	8916.0
CATSPER3	9622.0

---

REACTOME_RECOGNITION_AND_ASSOCIATION_OF_DNA_GLYCOSYLASE_WITH_SITE_CONTAINING_AN_AFFECTED_PURINE

REACTOME_RECOGNITION_AND_ASSOCIATION_OF_DNA_GLYCOSYLASE_WITH_SITE_CONTAINING_AN_AFFECTED_PURINE

	9
set	REACTOME_RECOGNITION_AND_ASSOCIATION_OF_DNA_GLYCOSYLASE_WITH_SITE_CONTAINING_AN_AFFECTED_PURINE
setSize	52
pANOVA	1.13e-06
s.dist	-0.39
p.adjustANOVA	4.23e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
H2AC7	-8983.5
H2BC7	-8983.5
H4C5	-8410.0
H2AZ1	-8280.0
H2BC10	-8128.0
TERF2IP	-8102.0
H2AC8	-7580.0
H4C6	-7171.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
H2AC7	-8983.5
H2BC7	-8983.5
H4C5	-8410.0
H2AZ1	-8280.0
H2BC10	-8128.0
TERF2IP	-8102.0
H2AC8	-7580.0
H4C6	-7171.0
TERF1	-6818.0
H2BC11	-6443.0
H2AJ	-5812.0
H4C12	-5632.0
H4C2	-5172.0
H2BC15	-5136.0
TINF2	-4952.0
H4C4	-4850.0
H2BC8	-4740.0
H2AX	-4613.0
H4C9	-4394.0
H2BC12	-3934.0
H2BC6	-3615.0
H2AC14	-3153.0
H2BC1	-3120.0
OGG1	-2484.0
H4C16	-2435.0
H2BC21	-1800.0
H2AC20	-444.0
H4C1	-204.0
MPG	-194.0
H2BC4	586.0
H2BC26	1116.0
MUTYH	3533.0
H2AC6	3867.0
H2AZ2	4572.0
TERF2	5034.0
ACD	5204.5
NEIL3	5789.0
POT1	6490.0
H3-4	7838.0
H4C13	8916.0

---

REACTOME_HDACS_DEACETYLATE_HISTONES

REACTOME_HDACS_DEACETYLATE_HISTONES

	548
set	REACTOME_HDACS_DEACETYLATE_HISTONES
setSize	85
pANOVA	1.24e-06
s.dist	-0.304
p.adjustANOVA	4.53e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2AC17	-10139.0
H2AC11	-9981.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
SAP30	-9654.0
H2BC5	-9558.0
H2AC4	-9538.0
SAP18	-9497.0
ARID4A	-9299.0
H3C3	-9117.0
H2AC7	-8983.5

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2AC17	-10139.0
H2AC11	-9981.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
SAP30	-9654.0
H2BC5	-9558.0
H2AC4	-9538.0
SAP18	-9497.0
ARID4A	-9299.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
HMG20B	-8919.0
H4C5	-8410.0
H3C4	-8401.0
REST	-8152.0
H2BC10	-8128.0
H2AC13	-8049.0
H2AC8	-7580.0
H3C10	-7442.0
H4C6	-7171.0
ARID4B	-6686.0
GATAD2B	-6523.0
H2BC11	-6443.0
H2AC15	-6141.0
H3C8	-5893.0
H4C12	-5632.0
H2AC21	-5508.0
H4C2	-5172.0
H2BC15	-5136.0
H4C4	-4850.0
H3C1	-4828.0
H2BC8	-4740.0
H4C9	-4394.0
H3C6	-4228.0
GPS2	-4154.0
H2BC12	-3934.0
H2BC6	-3615.0
H2AC14	-3153.0
H2BC1	-3120.0
RBBP4	-2675.0
H4C16	-2435.0
H3C11	-2128.0
H2AC1	-2117.0
H2BC21	-1800.0
TBL1XR1	-1412.0
NCOR1	-527.0
H2AC20	-444.0
H4C1	-204.0
HDAC1	78.0
MTA3	331.0
H2BC4	586.0
RCOR1	593.0
H2AC12	616.0
H2BC26	1116.0
H2AC16	1482.0
PHF21A	2035.0
KDM1A	2071.0
H2AC25	2805.0
HDAC2	2992.0
MTA2	3356.0
H2AC6	3867.0
BRMS1	4051.0
HDAC10	4527.0
GATAD2A	5020.0
CHD4	5360.0
SAP30L	5794.0
SUDS3	6117.0
H3C12	6531.0
HDAC3	6994.0
H3C2	7476.0
MBD3	7891.0
CHD3	8734.0
H4C13	8916.0
NCOR2	9123.0
MTA1	9526.0

---

REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION

REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION

	437
set	REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION
setSize	138
pANOVA	1.27e-06
s.dist	-0.239
p.adjustANOVA	4.55e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
POLR1E	-10495.0
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
SAP30	-9654.0
H2BC5	-9558.0
TBP	-9553.0
H2AC4	-9538.0
SAP18	-9497.0
H3C3	-9117.0
SIN3A	-9018.0
H2AC7	-8983.5

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
POLR1E	-10495.0
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
SAP30	-9654.0
H2BC5	-9558.0
TBP	-9553.0
H2AC4	-9538.0
SAP18	-9497.0
H3C3	-9117.0
SIN3A	-9018.0
H2AC7	-8983.5
H2BC7	-8983.5
ACTB	-8412.0
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0
POLR1H	-8215.0
H2BC10	-8128.0
H2AC8	-7580.0
AEBP2	-7517.0
POLR2E	-7485.0
H3C10	-7442.0
DDX21	-7212.0
TAF1D	-7196.0
H4C6	-7171.0
GSK3B	-6981.0
RRP8	-6863.0
ARID4B	-6686.0
GATAD2B	-6523.0
H2BC11	-6443.0
GTF2H3	-6340.0
POLR1C	-6163.0
H3C8	-5893.0
POLR1G	-5845.0
CDK7	-5825.0
H2AJ	-5812.0
KAT2B	-5664.0
H4C12	-5632.0
MNAT1	-5299.0
H4C2	-5172.0
H2BC15	-5136.0
CCNH	-4866.0
H4C4	-4850.0
H3C1	-4828.0
SMARCA5	-4808.0
EED	-4751.0
H2BC8	-4740.0
POLR1F	-4737.0
BAZ1B	-4618.0
H2AX	-4613.0
POLR1B	-4549.0
EP300	-4543.0
H4C9	-4394.0
H3C6	-4228.0
H2BC12	-3934.0
SUZ12	-3901.0
PHF1	-3724.0
POLR2F	-3657.0
H2BC6	-3615.0
MBD2	-3520.0
UBTF	-3295.0
H2AC14	-3153.0
H2BC1	-3120.0
GTF2H5	-3090.0
POLR2H	-2710.0
RBBP4	-2675.0
CBX3	-2592.0
UHRF1	-2453.0
H4C16	-2435.0
H3C11	-2128.0
TTF1	-2113.0
TAF1B	-1985.0
H2BC21	-1800.0
TET3	-1654.0
SF3B1	-1499.0
SAP130	-1325.0
POLR1D	-1301.0
SIRT1	-1075.0
H3-3A	-1031.0
H3-3B	-813.0
POLR2K	-624.0
H2AC20	-444.0
POLR2L	-372.0
H4C1	-204.0
KAT2A	-148.0
HDAC1	78.0
MTA3	331.0
MYO1C	544.0
H2BC4	586.0
ERCC2	1041.0
H2BC26	1116.0
DNMT3B	1176.0
TDG	1762.0
JARID2	1891.0
GTF2H1	2125.0
EZH2	2131.0
POLR1A	2501.0
HDAC2	2992.0
SAP30BP	3191.0
DNMT3L	3346.0
MTA2	3356.0
BAZ2A	3715.0
TET1	3752.0
ERCC6	3768.0
H2AC6	3867.0
DEK	3890.0
PHF19	4175.0
MTF2	4313.0
TET2	4386.0
H2AZ2	4572.0
TAF1A	4620.0
GATAD2A	5020.0
SIN3B	5045.0
CHD4	5360.0
DNMT1	5467.0
GTF2H4	5742.0
SAP30L	5794.0
SUDS3	6117.0
DNMT3A	6119.0
H3C12	6531.0
MYBBP1A	6607.0
H3C2	7476.0
EHMT2	7491.0
MBD3	7891.0
TAF1C	8532.0
ERCC3	8718.0
CHD3	8734.0
H4C13	8916.0
MTA1	9526.0

---

REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA

REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA

	1146
set	REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA
setSize	263
pANOVA	1.31e-06
s.dist	-0.173
p.adjustANOVA	4.58e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ZCRB1	-10430
RBM8A	-10237
POLR2J	-10179
CDC5L	-10151
PCF11	-10113
SEH1L	-10060
METTL3	-10033
HSPA8	-9899
SRSF10	-9852
POLR2I	-9848
NUDT21	-9812
FAM32A	-9738
HNRNPA1	-9569
ISY1	-9568
SNRNP25	-9549
SAP18	-9497
WBP11	-9463
PAPOLA	-9460
SNRNP35	-9443
SNRPD2	-9397

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ZCRB1	-10430.0
RBM8A	-10237.0
POLR2J	-10179.0
CDC5L	-10151.0
PCF11	-10113.0
SEH1L	-10060.0
METTL3	-10033.0
HSPA8	-9899.0
SRSF10	-9852.0
POLR2I	-9848.0
NUDT21	-9812.0
FAM32A	-9738.0
HNRNPA1	-9569.0
ISY1	-9568.0
SNRNP25	-9549.0
SAP18	-9497.0
WBP11	-9463.0
PAPOLA	-9460.0
SNRNP35	-9443.0
SNRPD2	-9397.0
HNRNPA3	-9386.0
PRPF38A	-9327.0
NUP42	-9274.0
NUP43	-9181.0
SRSF1	-9112.0
RNPC3	-8901.0
PCBP1	-8864.0
SRSF11	-8835.0
U2SURP	-8815.0
NUP107	-8608.0
YBX1	-8570.0
SNW1	-8558.0
NSRP1	-8509.0
THOC1	-8436.0
CPSF2	-8363.0
SNRPA	-8349.0
SDE2	-8240.0
WTAP	-8159.0
DDX39A	-8097.0
SNRNP48	-8067.0
THOC3	-8050.0
SNU13	-8031.0
CWC15	-8013.0
LUC7L3	-7956.0
NUP37	-7953.0
METTL14	-7932.0
NUP160	-7693.0
SARNP	-7620.5
HNRNPF	-7581.0
SRSF3	-7539.0
POLR2E	-7485.0
EFTUD2	-7349.0
HNRNPM	-7129.0
RBM22	-7035.0
LENG1	-7033.0
LSM6	-7013.0
BUD31	-7007.0
SF3B5	-6915.0
IK	-6869.0
ZC3H11A	-6721.0
DHX8	-6691.0
HNRNPL	-6643.0
AQR	-6633.0
UBL5	-6620.0
HNRNPA2B1	-6608.0
SNRPG	-6599.0
CPSF6	-6579.0
NUP50	-6564.0
SNRPD1	-6546.0
GLE1	-6241.0
SNRPD3	-6155.0
THOC5	-6040.0
CSTF3	-5991.0
SF3B3	-5896.0
SNRNP27	-5867.0
PRPF40A	-5857.0
SLBP	-5730.0
THOC6	-5609.0
MTREX	-5589.0
U2AF1L4	-5492.0
SF3B4	-5373.0
EIF4E	-5369.0
SNRPN	-5261.0
PPIL3	-5249.0
LSM3	-5062.0
NUP153	-5033.0
DDX46	-4997.0
PRPF4	-4948.0
MFAP1	-4914.0
SNIP1	-4809.0
ZNF830	-4785.0
SRSF5	-4675.0
POLR2C	-4652.0
LSM5	-4486.0
DDX5	-4382.0
CWC22	-4196.0
USP39	-4155.0
SNRPA1	-4090.0
PHF5A	-4072.0
RBM7	-3943.0
CSTF2T	-3889.0
POLDIP3	-3769.0
CWC27	-3756.0
HNRNPD	-3747.0
POLR2F	-3657.0
NUP155	-3436.0
DDX41	-3384.0
C9orf78	-3381.0
SRSF2	-3347.0
YJU2	-3304.0
MAGOHB	-3262.0
CWF19L2	-3221.0
ZMAT5	-3127.0
PPIE	-3077.0
CWC25	-3009.0
SF3A1	-2995.0
RBM25	-2917.0
TPR	-2890.0
POLR2H	-2710.0
PTBP1	-2639.0
SF3A3	-2560.0
SNRNP70	-2548.0
RBM42	-2524.0
NUP85	-2443.0
SRSF8	-2167.0
HNRNPU	-2019.0
DHX35	-2006.0
WBP4	-1992.0
NUP98	-1888.0
PPP1R8	-1842.0
RBM39	-1826.0
PLRG1	-1820.0
CPSF3	-1733.0
WDR33	-1722.0
DNAJC8	-1714.0
SNRNP40	-1675.0
DDX39B	-1629.0
POLR2G	-1573.0
SMU1	-1536.0
SRSF9	-1510.0
SF3B1	-1499.0
NXT1	-1374.0
CPSF7	-1371.0
SYF2	-1342.0
SNRPF	-1314.0
TRA2B	-1197.0
RBM17	-1151.0
PPIH	-1067.0
SNRPB2	-922.0
SF3B2	-881.0
CCDC12	-844.0
NXF1	-751.0
LSM4	-734.0
POLR2K	-624.0
TXNL4A	-621.0
PABPN1	-616.0
DDX23	-601.0
PRPF31	-470.0
PRKRIP1	-379.0
POLR2L	-372.0
NUP58	-237.0
BUD13	-181.0
SEC13	66.0
SLU7	114.0
LSM2	156.0
CDC40	172.0
PPIG	217.0
SRSF7	284.0
PNN	385.0
NUP35	446.0
LSM8	468.0
DDX42	528.0
CRNKL1	530.0
DHX15	644.0
CCAR1	909.0
SF3A2	917.0
HNRNPK	936.0
CHTOP	948.0
SMNDC1	1137.0
NCBP1	1140.0
FIP1L1	1178.0
PRCC	1204.0
ACIN1	1244.0
DHX38	1248.0
NUP88	1334.0
NDC1	1422.0
NUP214	1526.0
PDCD7	1682.0
FYTTD1	1764.0
POM121C	1782.0
RBM5	1838.0
CLP1	2178.0
ALYREF	2245.0
NUP188	2308.0
GCFC2	2667.0
SRRT	2712.0
NCBP2	2717.0
TCERG1	2768.0
NUP54	2991.0
SF1	3041.0
MAGOH	3043.0
PRPF19	3222.0
NUP133	3395.0
NUP62	3527.0
SNRPC	3554.0
SRSF6	3596.0
ZMAT2	3667.0
SUGP1	3735.0
HNRNPC	3774.0
PCBP2	3870.0
PRPF3	3877.0
WDR70	3897.0
GTF2F1	3903.0
PPIL1	3924.0
GTF2F2	3988.0
PPWD1	4075.0
CASC3	4135.0
RAE1	4292.0
GPATCH1	4300.0
THOC7	4498.0
NUP93	4585.0
AAAS	4604.0
RNPS1	4625.0
FUS	4914.0
PRPF18	4952.0
SRSF4	5167.0
POLR2D	5189.0
SRRM2	5217.0
NUP205	5228.0
CSTF1	5309.0
BCAS2	5488.0
SRRM1	5510.0
HNRNPR	5524.0
DHX16	5615.0
POLR2B	5721.0
RANBP2	5895.0
SNRPB	5980.0
PPIL4	6060.0
PRPF6	6065.0
SNRPE	6152.0
CHERP	6194.0
DHX9	6346.0
CACTIN	6468.0
TFIP11	6515.0
LSM7	6575.0
SNRNP200	6580.0
HNRNPH1	6766.0
POLR2A	7019.0
POM121	7060.0
EIF4A3	7144.0
CTNNBL1	7396.0
XAB2	7472.0
PPIL2	7752.0
SART1	8131.0
CPSF1	8200.0
PRPF8	8244.0
CPSF4	8260.0
PUF60	8431.0
U2AF2	8519.0
SRSF12	8610.0
SF3B6	9215.0
SYMPK	9413.0
NUP210	9431.0

---

REACTOME_HATS_ACETYLATE_HISTONES

REACTOME_HATS_ACETYLATE_HISTONES

	551
set	REACTOME_HATS_ACETYLATE_HISTONES
setSize	129
pANOVA	1.95e-06
s.dist	-0.243
p.adjustANOVA	6.55e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
MORF4L1	-10361.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2AC17	-10139.0
H2AC11	-9981.0
H2BC13	-9956.0
TAF9	-9926.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
YEATS4	-9240.0
H3C3	-9117.0
H2AC7	-8983.5

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
MORF4L1	-10361.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2AC17	-10139.0
H2AC11	-9981.0
H2BC13	-9956.0
TAF9	-9926.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
YEATS4	-9240.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
ATXN7L3	-8924.0
MSL1	-8915.0
ACTB	-8412.0
H4C5	-8410.0
H3C4	-8401.0
BRD8	-8228.0
H2BC10	-8128.0
TAF6L	-8070.0
H2AC13	-8049.0
TAF12	-8022.0
KAT7	-7736.0
H2AC8	-7580.0
H3C10	-7442.0
KAT5	-7394.0
H4C6	-7171.0
ELP5	-7078.0
MSL2	-6931.0
SUPT7L	-6727.0
MEAF6	-6696.0
H2BC11	-6443.0
MBIP	-6324.0
H2AC15	-6141.0
VPS72	-6015.0
H3C8	-5893.0
ATF2	-5831.0
TAF10	-5784.0
HAT1	-5716.0
KAT2B	-5664.0
H4C12	-5632.0
USP22	-5519.0
H2AC21	-5508.0
H4C2	-5172.0
H2BC15	-5136.0
TADA2A	-5085.0
H4C4	-4850.0
H3C1	-4828.0
H2BC8	-4740.0
EP300	-4543.0
RUVBL2	-4487.0
H4C9	-4394.0
H3C6	-4228.0
ELP3	-4220.0
H2BC12	-3934.0
H2BC6	-3615.0
H2AC14	-3153.0
H2BC1	-3120.0
H4C16	-2435.0
SUPT20H	-2221.0
H3C11	-2128.0
H2AC1	-2117.0
KANSL3	-1867.0
H2BC21	-1800.0
ENY2	-1784.0
BRPF3	-1690.0
RUVBL1	-1335.0
SAP130	-1325.0
KAT6A	-1269.0
ING4	-548.0
H2AC20	-444.0
TADA3	-417.0
ZZZ3	-371.0
H4C1	-204.0
ELP4	-190.0
KAT2A	-148.0
MCRS1	388.0
ATXN7	482.0
NCOA2	526.0
H2BC4	586.0
KANSL2	612.0
H2AC12	616.0
ING3	790.0
H2BC26	1116.0
ELP6	1170.0
H2AC16	1482.0
PAX3	1527.0
ELP1	1643.0
KANSL1	2050.0
ACTL6A	2338.0
JADE1	2638.0
JADE2	2704.0
DR1	2789.0
H2AC25	2805.0
BRPF1	2832.0
MRGBP	3519.0
ING5	3802.0
DMAP1	3833.0
H2AC6	3867.0
EPC1	4035.0
CREBBP	4616.0
KAT6B	4828.0
CLOCK	4971.0
YEATS2	5117.0
ELP2	5585.0
SUPT3H	5865.0
KAT8	6510.0
H3C12	6531.0
BRD1	6721.0
H3C2	7476.0
PHF20	7619.0
NCOA1	8118.0
EP400	8138.0
TADA2B	8154.0
WDR5	8384.0
H4C13	8916.0
TRRAP	8957.0
SGF29	9147.0
TADA1	10156.0
TAF5L	10158.0

---

REACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

REACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

	381
set	REACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX
setSize	85
pANOVA	1.96e-06
s.dist	-0.298
p.adjustANOVA	6.55e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
TLE2	-9159.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
TCF7	-8889.0
MYC	-8846.0
H4C5	-8410.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
TLE2	-9159.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
TCF7	-8889.0
MYC	-8846.0
H4C5	-8410.0
H3C4	-8401.0
H2AZ1	-8280.0
H2BC10	-8128.0
LEF1	-8061.0
PYGO2	-7607.0
H2AC8	-7580.0
H3C10	-7442.0
KAT5	-7394.0
H4C6	-7171.0
MEN1	-6843.0
H2BC11	-6443.0
TCF7L1	-6380.0
H3C8	-5893.0
H2AJ	-5812.0
H4C12	-5632.0
BCL9	-5565.0
H4C2	-5172.0
H2BC15	-5136.0
H4C4	-4850.0
H3C1	-4828.0
H2BC8	-4740.0
H2AX	-4613.0
EP300	-4543.0
H4C9	-4394.0
RBBP5	-4288.0
H3C6	-4228.0
H2BC12	-3934.0
TCF7L2	-3785.0
H2BC6	-3615.0
H2AC14	-3153.0
H2BC1	-3120.0
H4C16	-2435.0
CTNNB1	-2416.0
H3C11	-2128.0
H2BC21	-1800.0
RUVBL1	-1335.0
H3-3A	-1031.0
H3-3B	-813.0
TCF4	-593.0
H2AC20	-444.0
TLE4	-313.0
H4C1	-204.0
HDAC1	78.0
ASH2L	91.0
H2BC4	586.0
TLE1	956.0
H2BC26	1116.0
LEO1	2772.0
H2AC6	3867.0
SMARCA4	4099.0
RUNX3	4179.0
H2AZ2	4572.0
CREBBP	4616.0
PYGO1	5194.0
BCL9L	5267.0
H3C12	6531.0
TLE3	7268.0
H3C2	7476.0
H3-4	7838.0
CDC73	8020.0
TERT	8406.0
AXIN2	8766.0
H4C13	8916.0
TRRAP	8957.0
KMT2D	10859.0

---

REACTOME_HCMV_LATE_EVENTS

REACTOME_HCMV_LATE_EVENTS

	1466
set	REACTOME_HCMV_LATE_EVENTS
setSize	110
pANOVA	3.26e-06
s.dist	-0.257
p.adjustANOVA	0.000107

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
VPS37D	-10354.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2AC17	-10139.0
CHMP4C	-10126.0
SEH1L	-10060.0
H2AC11	-9981.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
NUP42	-9274.0
TSG101	-9209.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC18	-10545.5
H2AC19	-10545.5
H2BC17	-10413.0
VPS37D	-10354.0
H4C8	-10347.0
H2BC3	-10249.0
H2BC14	-10180.0
H4C3	-10142.0
H2AC17	-10139.0
CHMP4C	-10126.0
SEH1L	-10060.0
H2AC11	-9981.0
H2BC13	-9956.0
H2BC9	-9924.5
H3C7	-9924.5
H4C11	-9725.0
H2BC5	-9558.0
H2AC4	-9538.0
NUP42	-9274.0
TSG101	-9209.0
NUP43	-9181.0
H3C3	-9117.0
H2AC7	-8983.5
H2BC7	-8983.5
NUP107	-8608.0
H4C5	-8410.0
H3C4	-8401.0
H2BC10	-8128.0
H2AC13	-8049.0
NUP37	-7953.0
NUP160	-7693.0
H2AC8	-7580.0
CHMP1A	-7463.0
H3C10	-7442.0
H4C6	-7171.0
CHMP4B	-7128.0
NUP50	-6564.0
H2BC11	-6443.0
H2AC15	-6141.0
UBAP1	-6026.0
H3C8	-5893.0
H4C12	-5632.0
H2AC21	-5508.0
H4C2	-5172.0
H2BC15	-5136.0
NUP153	-5033.0
H4C4	-4850.0
H3C1	-4828.0
MVB12A	-4746.0
H2BC8	-4740.0
CHMP6	-4716.0
H4C9	-4394.0
H3C6	-4228.0
H2BC12	-3934.0
H2BC6	-3615.0
NUP155	-3436.0
CHMP2A	-3286.0
H2AC14	-3153.0
H2BC1	-3120.0
TPR	-2890.0
NUP85	-2443.0
H4C16	-2435.0
H3C11	-2128.0
H2AC1	-2117.0
NUP98	-1888.0
H2BC21	-1800.0
H2AC20	-444.0
CHMP3	-349.0
NUP58	-237.0
H4C1	-204.0
SEC13	66.0
VPS25	387.0
NUP35	446.0
H2BC4	586.0
H2AC12	616.0
HNRNPK	936.0
SNF8	1007.0
H2BC26	1116.0
NUP88	1334.0
NDC1	1422.0
H2AC16	1482.0
NUP214	1526.0
POM121C	1782.0
NUP188	2308.0
VPS37A	2358.0
H2AC25	2805.0
NUP54	2991.0
VPS36	3218.0
NUP133	3395.0
NUP62	3527.0
H2AC6	3867.0
RAE1	4292.0
NUP93	4585.0
AAAS	4604.0
NUP205	5228.0
VPS28	5306.0
RANBP2	5895.0
CHMP7	6267.0
VPS4A	6507.0
H3C12	6531.0
VPS37C	6765.0
POM121	7060.0
CHMP4A	7212.0
H3C2	7476.0
VPS37B	7718.0
CEBPD	8238.0
MVB12B	8883.0
H4C13	8916.0
NUP210	9431.0
CHMP2B	9475.0

---

Here is the session info with all the versions of packages used.

sessionInfo()

## R version 4.3.2 (2023-10-31)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.3 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3 
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so;  LAPACK version 3.10.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Etc/UTC
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.3.3                                      
##  [2] GGally_2.2.0                                       
##  [3] ggplot2_3.4.4                                      
##  [4] reshape2_1.4.4                                     
##  [5] gtools_3.9.5                                       
##  [6] tibble_3.2.1                                       
##  [7] dplyr_1.1.4                                        
##  [8] echarts4r_0.4.5                                    
##  [9] png_0.1-8                                          
## [10] gridExtra_2.3                                      
## [11] missMethyl_1.36.0                                  
## [12] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.1 
## [13] beeswarm_0.4.0                                     
## [14] kableExtra_1.3.4                                   
## [15] gplots_3.1.3                                       
## [16] mitch_1.15.0                                       
## [17] tictoc_1.2                                         
## [18] HGNChelper_0.8.1                                   
## [19] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [20] IlluminaHumanMethylation450kmanifest_0.4.0         
## [21] minfi_1.48.0                                       
## [22] bumphunter_1.44.0                                  
## [23] locfit_1.5-9.8                                     
## [24] iterators_1.0.14                                   
## [25] foreach_1.5.2                                      
## [26] Biostrings_2.70.1                                  
## [27] XVector_0.42.0                                     
## [28] SummarizedExperiment_1.32.0                        
## [29] Biobase_2.62.0                                     
## [30] MatrixGenerics_1.14.0                              
## [31] matrixStats_1.2.0                                  
## [32] GenomicRanges_1.54.1                               
## [33] GenomeInfoDb_1.38.2                                
## [34] IRanges_2.36.0                                     
## [35] S4Vectors_0.40.2                                   
## [36] BiocGenerics_0.48.1                                
## [37] eulerr_7.0.0                                       
## [38] limma_3.58.1                                       
## 
## loaded via a namespace (and not attached):
##   [1] splines_4.3.2             later_1.3.2              
##   [3] BiocIO_1.12.0             bitops_1.0-7             
##   [5] filelock_1.0.3            preprocessCore_1.64.0    
##   [7] XML_3.99-0.16             lifecycle_1.0.4          
##   [9] lattice_0.22-5            MASS_7.3-60              
##  [11] base64_2.0.1              scrime_1.3.5             
##  [13] magrittr_2.0.3            sass_0.4.8               
##  [15] rmarkdown_2.25            jquerylib_0.1.4          
##  [17] yaml_2.3.8                httpuv_1.6.13            
##  [19] doRNG_1.8.6               askpass_1.2.0            
##  [21] DBI_1.1.3                 RColorBrewer_1.1-3       
##  [23] abind_1.4-5               zlibbioc_1.48.0          
##  [25] rvest_1.0.3               quadprog_1.5-8           
##  [27] purrr_1.0.2               RCurl_1.98-1.13          
##  [29] rappdirs_0.3.3            GenomeInfoDbData_1.2.11  
##  [31] genefilter_1.84.0         annotate_1.80.0          
##  [33] svglite_2.1.3             DelayedMatrixStats_1.24.0
##  [35] codetools_0.2-19          DelayedArray_0.28.0      
##  [37] xml2_1.3.6                tidyselect_1.2.0         
##  [39] beanplot_1.3.1            BiocFileCache_2.10.1     
##  [41] webshot_0.5.5             illuminaio_0.44.0        
##  [43] GenomicAlignments_1.38.0  jsonlite_1.8.8           
##  [45] multtest_2.58.0           ellipsis_0.3.2           
##  [47] survival_3.5-7            systemfonts_1.0.5        
##  [49] tools_4.3.2               progress_1.2.3           
##  [51] Rcpp_1.0.11               glue_1.6.2               
##  [53] SparseArray_1.2.2         xfun_0.41                
##  [55] HDF5Array_1.30.0          withr_2.5.2              
##  [57] fastmap_1.1.1             rhdf5filters_1.14.1      
##  [59] fansi_1.0.6               openssl_2.1.1            
##  [61] caTools_1.18.2            digest_0.6.33            
##  [63] R6_2.5.1                  mime_0.12                
##  [65] colorspace_2.1-0          biomaRt_2.58.0           
##  [67] RSQLite_2.3.4             utf8_1.2.4               
##  [69] tidyr_1.3.0               generics_0.1.3           
##  [71] data.table_1.14.10        rtracklayer_1.62.0       
##  [73] prettyunits_1.2.0         httr_1.4.7               
##  [75] htmlwidgets_1.6.4         S4Arrays_1.2.0           
##  [77] ggstats_0.5.1             pkgconfig_2.0.3          
##  [79] gtable_0.3.4              blob_1.2.4               
##  [81] siggenes_1.76.0           htmltools_0.5.7          
##  [83] scales_1.3.0              rstudioapi_0.15.0        
##  [85] knitr_1.45                tzdb_0.4.0               
##  [87] rjson_0.2.21              nlme_3.1-163             
##  [89] curl_5.2.0                org.Hs.eg.db_3.18.0      
##  [91] cachem_1.0.8              rhdf5_2.46.1             
##  [93] stringr_1.5.1             KernSmooth_2.23-22       
##  [95] AnnotationDbi_1.64.1      restfulr_0.0.15          
##  [97] GEOquery_2.70.0           pillar_1.9.0             
##  [99] grid_4.3.2                reshape_0.8.9            
## [101] vctrs_0.6.5               promises_1.2.1           
## [103] dbplyr_2.4.0              xtable_1.8-4             
## [105] evaluate_0.23             readr_2.1.4              
## [107] GenomicFeatures_1.54.1    cli_3.6.2                
## [109] compiler_4.3.2            Rsamtools_2.18.0         
## [111] rlang_1.1.2               crayon_1.5.2             
## [113] rngtools_1.5.2            nor1mix_1.3-2            
## [115] mclust_6.0.1              plyr_1.8.9               
## [117] stringi_1.8.3             viridisLite_0.4.2        
## [119] BiocParallel_1.36.0       munsell_0.5.0            
## [121] Matrix_1.6-1.1            hms_1.1.3                
## [123] sparseMatrixStats_1.14.0  bit64_4.0.5              
## [125] Rhdf5lib_1.24.1           KEGGREST_1.42.0          
## [127] statmod_1.5.0             shiny_1.8.0              
## [129] highr_0.10                memoise_2.0.1            
## [131] bslib_0.6.1               bit_4.0.5

END of report