date generated: 2024-01-18

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch
x
A1BG 0.0016748
A1BG-AS1 0.0003792
A1CF -0.0001372
A2M 0.0005329
A2M-AS1 0.0057750
A2ML1 0.0028733

Here are some metrics about the input data profile:

Profiling data metrics
Profile metrics
num_genesets 1654
num_genes_in_profile 22007
duplicated_genes_present 0
num_profile_genes_in_sets 10383
num_profile_genes_not_in_sets 11624

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets: c2.cp.reactome.v2023.1.Hs.symbols.gmt
Gene set metrics
Gene sets metrics
num_genesets 1654
num_genesets_excluded 365
num_genesets_included 1289

Differential pathway expression


Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

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set setSize pANOVA s.dist p.adjustANOVA
REACTOME OLFACTORY SIGNALING PATHWAY 348 6.18e-07 -0.1560 0.00101
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE 105 2.83e-06 -0.2640 0.00149
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY 94 3.46e-06 -0.2770 0.00149
REACTOME EUKARYOTIC TRANSLATION ELONGATION 87 3.63e-06 -0.2870 0.00149
REACTOME NONSENSE MEDIATED DECAY NMD 107 1.43e-05 -0.2430 0.00470
REACTOME INFLUENZA INFECTION 149 2.14e-05 -0.2020 0.00579
REACTOME TRANSLATION 278 2.47e-05 -0.1470 0.00579
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS 161 4.26e-05 -0.1870 0.00874
REACTOME SELENOAMINO ACID METABOLISM 108 1.64e-04 -0.2100 0.02990
REACTOME EUKARYOTIC TRANSLATION INITIATION 110 1.99e-04 -0.2050 0.03220
REACTOME SENSORY PERCEPTION 555 2.15e-04 -0.0918 0.03220
REACTOME INNATE IMMUNE SYSTEM 1002 7.90e-04 0.0627 0.10200
REACTOME OPIOID SIGNALLING 89 8.08e-04 0.2050 0.10200
REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS 81 9.10e-04 0.2130 0.10700
REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN 37 1.05e-03 0.3110 0.11500
REACTOME MATURATION OF PROTEIN 3A 9 1.14e-03 0.6260 0.11700
REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE 109 1.77e-03 0.1730 0.17100
REACTOME PLATELET CALCIUM HOMEOSTASIS 27 2.02e-03 0.3430 0.17400
REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL 13 2.03e-03 0.4940 0.17400
REACTOME CA DEPENDENT EVENTS 36 2.18e-03 0.2950 0.17400
REACTOME DAG AND IP3 SIGNALING 40 2.26e-03 0.2790 0.17400
REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS 299 2.44e-03 0.1020 0.17400
REACTOME IRE1ALPHA ACTIVATES CHAPERONES 48 2.46e-03 0.2530 0.17400
REACTOME CELLULAR RESPONSE TO STARVATION 147 2.76e-03 -0.1430 0.17400
REACTOME SIGNALING BY ROBO RECEPTORS 206 2.78e-03 -0.1210 0.17400
REACTOME HEMOSTASIS 591 2.78e-03 0.0720 0.17400
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY 33 2.86e-03 -0.3000 0.17400
REACTOME RAB REGULATION OF TRAFFICKING 110 3.16e-03 0.1630 0.17400
REACTOME LEISHMANIA INFECTION 156 3.17e-03 0.1370 0.17400
REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS 62 3.18e-03 0.2170 0.17400
REACTOME METABOLISM OF LIPIDS 709 3.37e-03 0.0646 0.17800
REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY 26 3.57e-03 0.3300 0.18000
REACTOME METABOLISM OF CARBOHYDRATES 279 3.62e-03 0.1010 0.18000
REACTOME RAC2 GTPASE CYCLE 81 3.74e-03 0.1860 0.18100
REACTOME G PROTEIN BETA GAMMA SIGNALLING 30 3.86e-03 0.3050 0.18100
REACTOME G PROTEIN MEDIATED EVENTS 53 4.34e-03 0.2260 0.19800
REACTOME CALNEXIN CALRETICULIN CYCLE 26 4.56e-03 0.3210 0.20200
REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA 25 4.87e-03 0.3250 0.21000
REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS 418 5.24e-03 0.0796 0.21400
REACTOME O LINKED GLYCOSYLATION OF MUCINS 61 5.27e-03 0.2070 0.21400
REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS 33 5.33e-03 -0.2800 0.21400
REACTOME MEMBRANE TRAFFICKING 603 5.47e-03 0.0662 0.21400
REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX 15 5.83e-03 0.4110 0.22300
REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS 18 6.26e-03 0.3720 0.23000
REACTOME METABOLISM OF RNA 675 6.43e-03 -0.0615 0.23000
REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY 5 6.45e-03 0.7030 0.23000
REACTOME TRNA PROCESSING IN THE NUCLEUS 58 6.58e-03 -0.2060 0.23000
REACTOME RRNA PROCESSING 192 6.93e-03 -0.1130 0.23100
REACTOME RHOV GTPASE CYCLE 36 7.01e-03 0.2600 0.23100
REACTOME DISEASES OF IMMUNE SYSTEM 29 7.04e-03 0.2890 0.23100


Results (complete table)


Click HERE to show results for all gene sets

Complete results
set setSize pANOVA s.dist p.adjustANOVA
REACTOME OLFACTORY SIGNALING PATHWAY 348 6.18e-07 -0.156000 0.00101
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE 105 2.83e-06 -0.264000 0.00149
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY 94 3.46e-06 -0.277000 0.00149
REACTOME EUKARYOTIC TRANSLATION ELONGATION 87 3.63e-06 -0.287000 0.00149
REACTOME NONSENSE MEDIATED DECAY NMD 107 1.43e-05 -0.243000 0.00470
REACTOME INFLUENZA INFECTION 149 2.14e-05 -0.202000 0.00579
REACTOME TRANSLATION 278 2.47e-05 -0.147000 0.00579
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS 161 4.26e-05 -0.187000 0.00874
REACTOME SELENOAMINO ACID METABOLISM 108 1.64e-04 -0.210000 0.02990
REACTOME EUKARYOTIC TRANSLATION INITIATION 110 1.99e-04 -0.205000 0.03220
REACTOME SENSORY PERCEPTION 555 2.15e-04 -0.091800 0.03220
REACTOME INNATE IMMUNE SYSTEM 1002 7.90e-04 0.062700 0.10200
REACTOME OPIOID SIGNALLING 89 8.08e-04 0.205000 0.10200
REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS 81 9.10e-04 0.213000 0.10700
REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN 37 1.05e-03 0.311000 0.11500
REACTOME MATURATION OF PROTEIN 3A 9 1.14e-03 0.626000 0.11700
REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE 109 1.77e-03 0.173000 0.17100
REACTOME PLATELET CALCIUM HOMEOSTASIS 27 2.02e-03 0.343000 0.17400
REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL 13 2.03e-03 0.494000 0.17400
REACTOME CA DEPENDENT EVENTS 36 2.18e-03 0.295000 0.17400
REACTOME DAG AND IP3 SIGNALING 40 2.26e-03 0.279000 0.17400
REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS 299 2.44e-03 0.102000 0.17400
REACTOME IRE1ALPHA ACTIVATES CHAPERONES 48 2.46e-03 0.253000 0.17400
REACTOME CELLULAR RESPONSE TO STARVATION 147 2.76e-03 -0.143000 0.17400
REACTOME SIGNALING BY ROBO RECEPTORS 206 2.78e-03 -0.121000 0.17400
REACTOME HEMOSTASIS 591 2.78e-03 0.072000 0.17400
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY 33 2.86e-03 -0.300000 0.17400
REACTOME RAB REGULATION OF TRAFFICKING 110 3.16e-03 0.163000 0.17400
REACTOME LEISHMANIA INFECTION 156 3.17e-03 0.137000 0.17400
REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS 62 3.18e-03 0.217000 0.17400
REACTOME METABOLISM OF LIPIDS 709 3.37e-03 0.064600 0.17800
REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY 26 3.57e-03 0.330000 0.18000
REACTOME METABOLISM OF CARBOHYDRATES 279 3.62e-03 0.101000 0.18000
REACTOME RAC2 GTPASE CYCLE 81 3.74e-03 0.186000 0.18100
REACTOME G PROTEIN BETA GAMMA SIGNALLING 30 3.86e-03 0.305000 0.18100
REACTOME G PROTEIN MEDIATED EVENTS 53 4.34e-03 0.226000 0.19800
REACTOME CALNEXIN CALRETICULIN CYCLE 26 4.56e-03 0.321000 0.20200
REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA 25 4.87e-03 0.325000 0.21000
REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS 418 5.24e-03 0.079600 0.21400
REACTOME O LINKED GLYCOSYLATION OF MUCINS 61 5.27e-03 0.207000 0.21400
REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS 33 5.33e-03 -0.280000 0.21400
REACTOME MEMBRANE TRAFFICKING 603 5.47e-03 0.066200 0.21400
REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX 15 5.83e-03 0.411000 0.22300
REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS 18 6.26e-03 0.372000 0.23000
REACTOME METABOLISM OF RNA 675 6.43e-03 -0.061500 0.23000
REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY 5 6.45e-03 0.703000 0.23000
REACTOME TRNA PROCESSING IN THE NUCLEUS 58 6.58e-03 -0.206000 0.23000
REACTOME RRNA PROCESSING 192 6.93e-03 -0.113000 0.23100
REACTOME RHOV GTPASE CYCLE 36 7.01e-03 0.260000 0.23100
REACTOME DISEASES OF IMMUNE SYSTEM 29 7.04e-03 0.289000 0.23100
REACTOME ASPIRIN ADME 42 7.38e-03 -0.239000 0.23700
REACTOME HEME SIGNALING 47 7.65e-03 0.225000 0.23700
REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS 16 7.67e-03 0.385000 0.23700
REACTOME UNFOLDED PROTEIN RESPONSE UPR 88 7.79e-03 0.164000 0.23700
REACTOME IRAK4 DEFICIENCY TLR2 4 17 8.39e-03 0.369000 0.25100
REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS 11 8.99e-03 0.455000 0.26200
REACTOME TELOMERE C STRAND SYNTHESIS INITIATION 12 9.08e-03 -0.435000 0.26200
REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY 46 9.66e-03 -0.221000 0.27400
REACTOME VESICLE MEDIATED TRANSPORT 642 1.02e-02 0.059400 0.28000
REACTOME INOSITOL PHOSPHATE METABOLISM 45 1.06e-02 0.220000 0.28000
REACTOME PHOSPHOLIPID METABOLISM 201 1.06e-02 0.105000 0.28000
REACTOME COLLAGEN CHAIN TRIMERIZATION 42 1.08e-02 -0.227000 0.28000
REACTOME TRNA PROCESSING 105 1.09e-02 -0.144000 0.28000
REACTOME ER QUALITY CONTROL COMPARTMENT ERQC 21 1.09e-02 0.321000 0.28000
REACTOME POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE 25 1.16e-02 -0.292000 0.29200
REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION 74 1.18e-02 0.169000 0.29300
REACTOME RHOU GTPASE CYCLE 37 1.21e-02 0.238000 0.29300
REACTOME DRUG ADME 103 1.23e-02 -0.143000 0.29300
REACTOME GLYCOSAMINOGLYCAN METABOLISM 118 1.23e-02 0.133000 0.29300
REACTOME TOLL LIKE RECEPTOR 9 TLR9 CASCADE 100 1.26e-02 0.144000 0.29400
REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE 35 1.27e-02 0.243000 0.29400
REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN 76 1.41e-02 0.163000 0.32000
REACTOME MEIOTIC RECOMBINATION 80 1.42e-02 -0.159000 0.32000
REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS 32 1.49e-02 0.249000 0.32400
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION 250 1.49e-02 0.089400 0.32400
REACTOME TOLL LIKE RECEPTOR CASCADES 158 1.52e-02 0.112000 0.32400
REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB 19 1.53e-02 0.321000 0.32400
REACTOME SIGNALING BY MST1 5 1.54e-02 0.626000 0.32400
REACTOME FCGR3A MEDIATED IL10 SYNTHESIS 36 1.57e-02 0.233000 0.32600
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION 1356 1.59e-02 0.039000 0.32600
REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION 32 1.63e-02 0.245000 0.33100
REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION 42 1.67e-02 0.213000 0.33100
REACTOME DARPP 32 EVENTS 24 1.68e-02 0.282000 0.33100
REACTOME NUCLEAR IMPORT OF REV PROTEIN 34 1.69e-02 -0.237000 0.33100
REACTOME ADAPTIVE IMMUNE SYSTEM 729 1.74e-02 0.051700 0.33300
REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS 188 1.76e-02 0.100000 0.33300
REACTOME TRANSPORT OF SMALL MOLECULES 697 1.77e-02 0.052700 0.33300
REACTOME MITOCHONDRIAL TRANSLATION 93 1.81e-02 -0.142000 0.33600
REACTOME SUMOYLATION OF DNA REPLICATION PROTEINS 46 1.82e-02 -0.201000 0.33600
REACTOME RAC3 GTPASE CYCLE 85 1.84e-02 0.148000 0.33600
REACTOME INTERLEUKIN 1 SIGNALING 110 1.90e-02 0.129000 0.34100
REACTOME SIGNALING BY INSULIN RECEPTOR 80 1.91e-02 0.152000 0.34100
REACTOME MEIOSIS 110 2.02e-02 -0.128000 0.34200
REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE 69 2.02e-02 0.162000 0.34200
REACTOME RHO GTPASE CYCLE 423 2.03e-02 0.065800 0.34200
REACTOME SIALIC ACID METABOLISM 33 2.04e-02 0.233000 0.34200
REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS 23 2.11e-02 0.278000 0.34200
REACTOME NEUTROPHIL DEGRANULATION 460 2.13e-02 0.062700 0.34200
REACTOME ECM PROTEOGLYCANS 73 2.14e-02 -0.156000 0.34200
REACTOME ASPARAGINE N LINKED GLYCOSYLATION 299 2.16e-02 0.077200 0.34200
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE 11 2.17e-02 0.400000 0.34200
REACTOME ERYTHROPOIETIN ACTIVATES STAT5 7 2.17e-02 0.501000 0.34200
REACTOME INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS 37 2.18e-02 -0.218000 0.34200
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS 14 2.22e-02 0.353000 0.34200
REACTOME GPER1 SIGNALING 45 2.22e-02 0.197000 0.34200
REACTOME SNRNP ASSEMBLY 53 2.23e-02 -0.181000 0.34200
REACTOME SARS COV 2 HOST INTERACTIONS 191 2.23e-02 -0.095900 0.34200
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE 8 2.26e-02 0.465000 0.34200
REACTOME TACHYKININ RECEPTORS BIND TACHYKININS 5 2.27e-02 0.588000 0.34200
REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION 296 2.34e-02 0.076600 0.34400
REACTOME RHOB GTPASE CYCLE 67 2.36e-02 0.160000 0.34400
REACTOME NOTCH HLH TRANSCRIPTION PATHWAY 24 2.37e-02 0.267000 0.34400
REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX 36 2.37e-02 0.218000 0.34400
REACTOME CIRCADIAN CLOCK 68 2.43e-02 0.158000 0.35000
REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS 35 2.46e-02 -0.219000 0.35200
REACTOME HCMV LATE EVENTS 110 2.54e-02 -0.123000 0.35800
REACTOME VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS 42 2.55e-02 0.199000 0.35800
REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS 100 2.60e-02 -0.129000 0.36100
REACTOME C TYPE LECTIN RECEPTORS CLRS 136 2.69e-02 0.110000 0.37200
REACTOME ACYL CHAIN REMODELING OF DAG AND TAG 5 2.74e-02 0.569000 0.37300
REACTOME NUCLEOTIDE SALVAGE 21 2.77e-02 0.278000 0.37300
REACTOME PREDNISONE ADME 10 2.79e-02 -0.401000 0.37300
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1 25 2.80e-02 0.254000 0.37300
REACTOME PTK6 EXPRESSION 5 2.82e-02 0.567000 0.37300
REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE 66 2.92e-02 -0.155000 0.38400
REACTOME BIOSYNTHESIS OF MARESINS 8 3.04e-02 -0.442000 0.39600
REACTOME TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA 36 3.08e-02 -0.208000 0.39800
REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN 32 3.17e-02 -0.219000 0.40600
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE 5 3.22e-02 0.553000 0.40600
REACTOME ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION 16 3.23e-02 0.309000 0.40600
REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING 89 3.26e-02 0.131000 0.40600
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K 12 3.28e-02 0.356000 0.40600
REACTOME REPRODUCTION 136 3.29e-02 -0.106000 0.40600
REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS 6 3.40e-02 -0.500000 0.41700
REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES 101 3.44e-02 0.122000 0.41900
REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION 12 3.52e-02 0.351000 0.41900
REACTOME NRAGE SIGNALS DEATH THROUGH JNK 53 3.56e-02 0.167000 0.41900
REACTOME PEPTIDE HORMONE BIOSYNTHESIS 13 3.56e-02 0.337000 0.41900
REACTOME SUMOYLATION OF DNA METHYLATION PROTEINS 16 3.58e-02 0.303000 0.41900
REACTOME POST TRANSCRIPTIONAL SILENCING BY SMALL RNAS 7 3.59e-02 0.458000 0.41900
REACTOME RELAXIN RECEPTORS 8 3.65e-02 0.427000 0.41900
REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES 34 3.67e-02 0.207000 0.41900
REACTOME SUMOYLATION OF SUMOYLATION PROTEINS 35 3.67e-02 -0.204000 0.41900
REACTOME AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS 9 3.67e-02 0.402000 0.41900
REACTOME EXTRA NUCLEAR ESTROGEN SIGNALING 74 3.70e-02 0.140000 0.41900
REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP 41 3.74e-02 0.188000 0.42000
REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS 18 3.79e-02 -0.283000 0.42000
REACTOME GLYCOGEN METABOLISM 22 3.80e-02 0.256000 0.42000
REACTOME G ALPHA 12 13 SIGNALLING EVENTS 74 3.81e-02 0.139000 0.42000
REACTOME PD 1 SIGNALING 21 3.90e-02 -0.260000 0.42400
REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION 26 3.92e-02 0.234000 0.42400
REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES 34 3.98e-02 0.204000 0.42400
REACTOME CD28 CO STIMULATION 32 3.98e-02 0.210000 0.42400
REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS 13 3.98e-02 0.329000 0.42400
REACTOME PROTON COUPLED MONOCARBOXYLATE TRANSPORT 6 4.00e-02 0.484000 0.42400
REACTOME SIGNALING BY NOTCH3 48 4.07e-02 0.171000 0.42700
REACTOME VITAMIN C ASCORBATE METABOLISM 8 4.08e-02 0.418000 0.42700
REACTOME INTEGRIN CELL SURFACE INTERACTIONS 83 4.20e-02 -0.129000 0.42800
REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS 123 4.21e-02 0.106000 0.42800
REACTOME SIGNALING BY VEGF 102 4.22e-02 0.116000 0.42800
REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX 134 4.23e-02 -0.102000 0.42800
REACTOME RELEASE OF HH NP FROM THE SECRETING CELL 8 4.28e-02 -0.414000 0.42800
REACTOME FOLDING OF ACTIN BY CCT TRIC 10 4.29e-02 -0.370000 0.42800
REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS 12 4.30e-02 -0.337000 0.42800
REACTOME NUCLEAR PORE COMPLEX NPC DISASSEMBLY 36 4.30e-02 -0.195000 0.42800
REACTOME PRE NOTCH PROCESSING IN GOLGI 18 4.35e-02 0.275000 0.42900
REACTOME SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER 54 4.37e-02 0.159000 0.42900
REACTOME METALLOTHIONEINS BIND METALS 11 4.49e-02 -0.349000 0.43800
REACTOME PHENYLALANINE AND TYROSINE METABOLISM 11 4.53e-02 0.349000 0.43800
REACTOME TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS 29 4.54e-02 0.215000 0.43800
REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT 236 4.58e-02 0.075500 0.44000
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS 9 4.64e-02 0.383000 0.44100
REACTOME SIGNAL AMPLIFICATION 33 4.66e-02 0.200000 0.44100
REACTOME CD22 MEDIATED BCR REGULATION 5 4.67e-02 0.514000 0.44100
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION 361 4.74e-02 0.060800 0.44200
REACTOME NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 24 4.76e-02 0.234000 0.44200
REACTOME SIGNALING BY NUCLEAR RECEPTORS 283 4.77e-02 0.068400 0.44200
REACTOME OPSINS 7 4.96e-02 -0.428000 0.45700
REACTOME SCAVENGING BY CLASS A RECEPTORS 19 5.01e-02 -0.260000 0.45700
REACTOME G BETA GAMMA SIGNALLING THROUGH CDC42 19 5.02e-02 0.260000 0.45700
REACTOME SIGNALING BY FGFR IN DISEASE 62 5.06e-02 0.144000 0.45900
REACTOME FATTY ACYL COA BIOSYNTHESIS 36 5.16e-02 0.187000 0.46300
REACTOME REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM 11 5.18e-02 0.339000 0.46300
REACTOME SARS COV 1 HOST INTERACTIONS 92 5.18e-02 -0.117000 0.46300
REACTOME SCAVENGING BY CLASS F RECEPTORS 6 5.31e-02 0.456000 0.46700
REACTOME O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS 38 5.33e-02 -0.181000 0.46700
REACTOME TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS 52 5.39e-02 0.155000 0.46700
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA 263 5.40e-02 -0.069000 0.46700
REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING 13 5.42e-02 0.308000 0.46700
REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE 52 5.43e-02 -0.154000 0.46700
REACTOME REGULATION OF SIGNALING BY NODAL 9 5.51e-02 0.369000 0.46700
REACTOME MRNA SPLICING 197 5.51e-02 -0.079300 0.46700
REACTOME FATTY ACID METABOLISM 170 5.52e-02 0.085200 0.46700
REACTOME G PROTEIN ACTIVATION 24 5.52e-02 0.226000 0.46700
REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS 83 5.60e-02 0.121000 0.46800
REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS 28 5.60e-02 0.209000 0.46800
REACTOME PROTEIN REPAIR 6 5.62e-02 0.450000 0.46800
REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R 52 5.77e-02 0.152000 0.47600
REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES 7 5.81e-02 0.414000 0.47600
REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF 53 5.83e-02 0.150000 0.47600
REACTOME GLUCURONIDATION 23 5.85e-02 -0.228000 0.47600
REACTOME MRNA EDITING 10 5.88e-02 0.345000 0.47600
REACTOME RUNX3 REGULATES NOTCH SIGNALING 13 5.89e-02 0.303000 0.47600
REACTOME RET SIGNALING 40 5.92e-02 0.172000 0.47600
REACTOME REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE 81 6.01e-02 -0.121000 0.47900
REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION 60 6.01e-02 -0.140000 0.47900
REACTOME HCMV EARLY EVENTS 128 6.09e-02 -0.095900 0.47900
REACTOME INSULIN RECEPTOR RECYCLING 29 6.11e-02 0.201000 0.47900
REACTOME COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES 65 6.17e-02 -0.134000 0.47900
REACTOME LIPOPHAGY 9 6.18e-02 -0.360000 0.47900
REACTOME CONDENSATION OF PROPHASE CHROMOSOMES 66 6.20e-02 -0.133000 0.47900
REACTOME NS1 MEDIATED EFFECTS ON HOST PATHWAYS 41 6.21e-02 -0.168000 0.47900
REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS 63 6.21e-02 0.136000 0.47900
REACTOME RHO GTPASES ACTIVATE PKNS 86 6.38e-02 -0.116000 0.48200
REACTOME REGULATION BY C FLIP 11 6.42e-02 -0.322000 0.48200
REACTOME MET RECEPTOR ACTIVATION 6 6.45e-02 0.436000 0.48200
REACTOME LYSOSOME VESICLE BIOGENESIS 33 6.45e-02 0.186000 0.48200
REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS 16 6.47e-02 0.267000 0.48200
REACTOME SULFIDE OXIDATION TO SULFATE 6 6.52e-02 0.435000 0.48200
REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 44 6.52e-02 0.161000 0.48200
REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE 277 6.55e-02 0.064300 0.48200
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S 53 6.55e-02 -0.146000 0.48200
REACTOME ACTIVATION OF TRKA RECEPTORS 6 6.58e-02 -0.434000 0.48200
REACTOME MYD88 INDEPENDENT TLR4 CASCADE 103 6.59e-02 0.105000 0.48200
REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE 63 6.61e-02 -0.134000 0.48200
REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION 31 6.64e-02 0.190000 0.48300
REACTOME CONJUGATION OF BENZOATE WITH GLYCINE 6 6.92e-02 -0.428000 0.50100
REACTOME MITOTIC PROPHASE 134 7.07e-02 -0.090400 0.50900
REACTOME DISSOLUTION OF FIBRIN CLOT 13 7.18e-02 0.288000 0.51000
REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES 80 7.20e-02 -0.116000 0.51000
REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS 23 7.22e-02 0.217000 0.51000
REACTOME BASE EXCISION REPAIR 87 7.28e-02 -0.111000 0.51000
REACTOME MEIOTIC SYNAPSIS 73 7.29e-02 -0.121000 0.51000
REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES 91 7.31e-02 0.109000 0.51000
REACTOME SYNTHESIS OF UDP N ACETYL GLUCOSAMINE 7 7.34e-02 0.391000 0.51000
REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS 51 7.36e-02 0.145000 0.51000
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION 29 7.36e-02 0.192000 0.51000
REACTOME RAC1 GTPASE CYCLE 172 7.48e-02 0.078700 0.51200
REACTOME TELOMERE C STRAND LAGGING STRAND SYNTHESIS 33 7.51e-02 -0.179000 0.51200
REACTOME IRS MEDIATED SIGNALLING 47 7.51e-02 0.150000 0.51200
REACTOME EXTRACELLULAR MATRIX ORGANIZATION 291 7.52e-02 -0.060600 0.51200
REACTOME GDP FUCOSE BIOSYNTHESIS 6 7.69e-02 0.417000 0.52000
REACTOME INTERLEUKIN 9 SIGNALING 7 7.70e-02 0.386000 0.52000
REACTOME GENE SILENCING BY RNA 133 7.83e-02 -0.088400 0.52100
REACTOME SARS COV 2 ACTIVATES MODULATES INNATE AND ADAPTIVE IMMUNE RESPONSES 118 7.87e-02 -0.093700 0.52100
REACTOME CHROMOSOME MAINTENANCE 130 7.88e-02 -0.089300 0.52100
REACTOME INTERLEUKIN 1 FAMILY SIGNALING 146 7.89e-02 0.084200 0.52100
REACTOME FORMATION OF XYLULOSE 5 PHOSPHATE 5 7.90e-02 0.454000 0.52100
REACTOME ENDOSOMAL VACUOLAR PATHWAY 11 7.98e-02 -0.305000 0.52100
REACTOME SIGNALING BY RECEPTOR TYROSINE KINASES 507 7.98e-02 0.045400 0.52100
REACTOME CD209 DC SIGN SIGNALING 20 8.03e-02 0.226000 0.52100
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12 22 8.05e-02 0.215000 0.52100
REACTOME TRIF MEDIATED PROGRAMMED CELL DEATH 9 8.06e-02 0.336000 0.52100
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES 8 8.06e-02 0.357000 0.52100
REACTOME SIGNALING BY NOTCH1 69 8.10e-02 0.121000 0.52100
REACTOME CIPROFLOXACIN ADME 5 8.37e-02 -0.447000 0.53200
REACTOME KEAP1 NFE2L2 PATHWAY 104 8.39e-02 0.098100 0.53200
REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE 93 8.40e-02 0.104000 0.53200
REACTOME PHENYLALANINE METABOLISM 6 8.41e-02 0.407000 0.53200
REACTOME CDC42 GTPASE CYCLE 144 8.46e-02 0.083300 0.53200
REACTOME CA2 PATHWAY 62 8.51e-02 0.126000 0.53200
REACTOME NEGATIVE REGULATION OF MET ACTIVITY 20 8.52e-02 0.222000 0.53200
REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE 48 8.52e-02 0.144000 0.53200
REACTOME ESTROGEN BIOSYNTHESIS 6 8.67e-02 -0.404000 0.53300
REACTOME PKA ACTIVATION IN GLUCAGON SIGNALLING 17 8.69e-02 0.240000 0.53300
REACTOME IRON UPTAKE AND TRANSPORT 56 8.70e-02 0.132000 0.53300
REACTOME DISEASES OF BASE EXCISION REPAIR 5 8.71e-02 0.442000 0.53300
REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES 18 8.74e-02 -0.233000 0.53300
REACTOME TRANS GOLGI NETWORK VESICLE BUDDING 67 8.76e-02 0.121000 0.53300
REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS 21 8.76e-02 0.215000 0.53300
REACTOME RECEPTOR MEDIATED MITOPHAGY 10 8.83e-02 0.311000 0.53500
REACTOME PLATELET HOMEOSTASIS 85 8.92e-02 0.107000 0.53800
REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS 91 8.98e-02 -0.103000 0.53900
REACTOME SIGNALING BY ERYTHROPOIETIN 25 9.03e-02 0.196000 0.53900
REACTOME ONCOGENIC MAPK SIGNALING 79 9.08e-02 0.110000 0.53900
REACTOME BASE EXCISION REPAIR AP SITE FORMATION 59 9.09e-02 -0.127000 0.53900
REACTOME DEFECTIVE F9 ACTIVATION 5 9.09e-02 0.437000 0.53900
REACTOME VIRAL MESSENGER RNA SYNTHESIS 44 9.13e-02 -0.147000 0.53900
REACTOME NEUROTRANSMITTER RELEASE CYCLE 48 9.18e-02 -0.141000 0.54000
REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR 24 9.25e-02 0.198000 0.54000
REACTOME NR1H2 AND NR1H3 MEDIATED SIGNALING 46 9.27e-02 0.143000 0.54000
REACTOME PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1 9 9.28e-02 0.324000 0.54000
REACTOME RAB GERANYLGERANYLATION 57 9.36e-02 0.128000 0.54000
REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES 353 9.39e-02 -0.051900 0.54000
REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM 78 9.41e-02 -0.110000 0.54000
REACTOME CHROMATIN MODIFYING ENZYMES 252 9.41e-02 0.061200 0.54000
REACTOME SEROTONIN RECEPTORS 11 9.69e-02 -0.289000 0.55400
REACTOME SIGNALING BY FGFR1 IN DISEASE 38 9.77e-02 0.155000 0.55700
REACTOME MET INTERACTS WITH TNS PROTEINS 5 9.81e-02 0.427000 0.55700
REACTOME GENERATION OF SECOND MESSENGER MOLECULES 30 9.89e-02 -0.174000 0.56000
REACTOME RHOG GTPASE CYCLE 71 9.92e-02 0.113000 0.56000
REACTOME GLUCOCORTICOID BIOSYNTHESIS 10 9.96e-02 -0.301000 0.56000
REACTOME LYSINE CATABOLISM 12 1.00e-01 -0.274000 0.56100
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1 229 1.01e-01 0.062900 0.56500
REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES 21 1.01e-01 -0.206000 0.56500
REACTOME POTENTIAL THERAPEUTICS FOR SARS 92 1.03e-01 0.098300 0.57200
REACTOME ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE 9 1.04e-01 0.313000 0.57200
REACTOME AURKA ACTIVATION BY TPX2 69 1.04e-01 0.113000 0.57200
REACTOME POLYMERASE SWITCHING 13 1.05e-01 -0.260000 0.57700
REACTOME REDUCTION OF CYTOSOLIC CA LEVELS 11 1.05e-01 0.282000 0.57700
REACTOME REGULATION OF NPAS4 GENE EXPRESSION 13 1.07e-01 0.258000 0.57800
REACTOME CELL CELL COMMUNICATION 126 1.07e-01 0.083000 0.57800
REACTOME SUMOYLATION OF UBIQUITINYLATION PROTEINS 39 1.08e-01 -0.149000 0.57800
REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR 19 1.08e-01 0.213000 0.57800
REACTOME P2Y RECEPTORS 9 1.08e-01 0.309000 0.57800
REACTOME CELL JUNCTION ORGANIZATION 89 1.08e-01 0.098500 0.57800
REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX 9 1.09e-01 0.309000 0.57800
REACTOME RNA POLYMERASE I PROMOTER ESCAPE 83 1.09e-01 -0.102000 0.57800
REACTOME MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS 13 1.10e-01 0.256000 0.57800
REACTOME RND2 GTPASE CYCLE 42 1.10e-01 0.142000 0.57800
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE 5 1.10e-01 0.412000 0.57800
REACTOME ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS 7 1.11e-01 0.348000 0.57800
REACTOME COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC 52 1.11e-01 0.128000 0.57800
REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION 62 1.12e-01 -0.117000 0.57800
REACTOME INTRA GOLGI TRAFFIC 43 1.12e-01 0.140000 0.57800
REACTOME RHO GTPASES ACTIVATE CIT 19 1.12e-01 -0.211000 0.57800
REACTOME RECYCLING PATHWAY OF L1 43 1.12e-01 0.140000 0.57800
REACTOME VITAMIN B5 PANTOTHENATE METABOLISM 16 1.12e-01 0.229000 0.57800
REACTOME METAL ION SLC TRANSPORTERS 23 1.12e-01 0.191000 0.57800
REACTOME CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER 25 1.13e-01 0.183000 0.58200
REACTOME DISEASES OF PROGRAMMED CELL DEATH 96 1.14e-01 -0.093300 0.58500
REACTOME PROGRAMMED CELL DEATH 204 1.18e-01 0.063500 0.59800
REACTOME CAMK IV MEDIATED PHOSPHORYLATION OF CREB 10 1.18e-01 0.285000 0.59800
REACTOME CELLULAR HEXOSE TRANSPORT 21 1.19e-01 0.197000 0.59800
REACTOME WNT MEDIATED ACTIVATION OF DVL 8 1.19e-01 0.319000 0.59800
REACTOME PROPIONYL COA CATABOLISM 5 1.19e-01 0.403000 0.59800
REACTOME ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION 28 1.19e-01 0.170000 0.59800
REACTOME RUNX3 REGULATES BCL2L11 BIM TRANSCRIPTION 5 1.21e-01 0.400000 0.60500
REACTOME SIGNALING BY SCF KIT 42 1.22e-01 0.138000 0.60500
REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV 1 INFECTION 5 1.22e-01 -0.400000 0.60500
REACTOME NCAM1 INTERACTIONS 41 1.22e-01 -0.140000 0.60500
REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS 55 1.23e-01 -0.120000 0.60800
REACTOME METABOLISM OF PORPHYRINS 26 1.23e-01 -0.175000 0.60800
REACTOME SIGNALING BY NOTCH2 32 1.24e-01 0.157000 0.60900
REACTOME RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA 7 1.25e-01 -0.335000 0.61100
REACTOME CATION COUPLED CHLORIDE COTRANSPORTERS 7 1.26e-01 0.334000 0.61200
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS 5 1.26e-01 0.395000 0.61200
REACTOME SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL 8 1.27e-01 0.312000 0.61700
REACTOME NOSTRIN MEDIATED ENOS TRAFFICKING 5 1.29e-01 0.392000 0.61800
REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES 78 1.29e-01 0.099500 0.61800
REACTOME SYNTHESIS OF PC 27 1.29e-01 0.169000 0.61800
REACTOME FBXW7 MUTANTS AND NOTCH1 IN CANCER 5 1.29e-01 0.392000 0.61800
REACTOME CREB PHOSPHORYLATION 6 1.29e-01 0.358000 0.61800
REACTOME APOPTOTIC EXECUTION PHASE 49 1.30e-01 0.125000 0.62100
REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE 9 1.31e-01 -0.291000 0.62200
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL 24 1.32e-01 0.177000 0.62500
REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 122 1.33e-01 0.078700 0.62500
REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM 45 1.33e-01 0.129000 0.62500
REACTOME RHOD GTPASE CYCLE 49 1.33e-01 0.124000 0.62500
REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX 85 1.34e-01 -0.094000 0.62500
REACTOME SYNTHESIS OF PG 8 1.34e-01 0.306000 0.62500
REACTOME DEATH RECEPTOR SIGNALING 143 1.35e-01 0.072500 0.62500
REACTOME MITOTIC TELOPHASE CYTOKINESIS 11 1.35e-01 -0.260000 0.62500
REACTOME P38MAPK EVENTS 13 1.35e-01 0.240000 0.62500
REACTOME PI METABOLISM 79 1.35e-01 0.097100 0.62600
REACTOME SUMOYLATION OF INTRACELLULAR RECEPTORS 29 1.36e-01 0.160000 0.62600
REACTOME MYOGENESIS 29 1.36e-01 0.160000 0.62600
REACTOME ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS 24 1.37e-01 0.175000 0.62700
REACTOME LIPID PARTICLE ORGANIZATION 6 1.37e-01 -0.350000 0.62700
REACTOME CYCLIN D ASSOCIATED EVENTS IN G1 46 1.38e-01 0.126000 0.62700
REACTOME DAP12 SIGNALING 27 1.38e-01 -0.165000 0.62700
REACTOME RHOBTB1 GTPASE CYCLE 22 1.39e-01 -0.182000 0.62700
REACTOME ESR MEDIATED SIGNALING 210 1.40e-01 0.059200 0.62700
REACTOME NEDDYLATION 235 1.40e-01 0.055900 0.62700
REACTOME PURINE SALVAGE 12 1.40e-01 0.246000 0.62700
REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC 28 1.40e-01 -0.161000 0.62700
REACTOME TELOMERE MAINTENANCE 106 1.41e-01 -0.082900 0.62700
REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE 52 1.42e-01 0.118000 0.62700
REACTOME REGULATION OF BACH1 ACTIVITY 11 1.42e-01 0.255000 0.62700
REACTOME TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS 43 1.43e-01 -0.129000 0.62700
REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 100 1.43e-01 -0.084700 0.62700
REACTOME ACTIVATION OF PPARGC1A PGC 1ALPHA BY PHOSPHORYLATION 10 1.43e-01 -0.267000 0.62700
REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX 32 1.43e-01 0.149000 0.62700
REACTOME G2 M DNA DAMAGE CHECKPOINT 90 1.43e-01 -0.089200 0.62700
REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS 12 1.44e-01 0.244000 0.62700
REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND 21 1.44e-01 0.184000 0.62700
REACTOME NEUREXINS AND NEUROLIGINS 51 1.44e-01 -0.118000 0.62800
REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION 13 1.47e-01 0.232000 0.63900
REACTOME TAK1 DEPENDENT IKK AND NF KAPPA B ACTIVATION 41 1.48e-01 0.131000 0.63900
REACTOME ACTIVATION OF BH3 ONLY PROTEINS 30 1.48e-01 0.153000 0.63900
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG 7 1.49e-01 0.315000 0.64100
REACTOME SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER 15 1.49e-01 0.215000 0.64100
REACTOME THE PHOTOTRANSDUCTION CASCADE 32 1.51e-01 0.147000 0.64700
REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK 111 1.54e-01 0.078400 0.65200
REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS 8 1.54e-01 -0.291000 0.65200
REACTOME NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 19 1.54e-01 0.189000 0.65200
REACTOME AQUAPORIN MEDIATED TRANSPORT 51 1.54e-01 0.115000 0.65200
REACTOME CREATINE METABOLISM 9 1.54e-01 0.274000 0.65200
REACTOME G ALPHA Q SIGNALLING EVENTS 206 1.55e-01 0.057500 0.65200
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE 20 1.55e-01 0.184000 0.65300
REACTOME REGULATION OF NF KAPPA B SIGNALING 17 1.55e-01 0.199000 0.65300
REACTOME PEPTIDE HORMONE METABOLISM 84 1.56e-01 0.089600 0.65300
REACTOME GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION 42 1.57e-01 0.126000 0.65300
REACTOME DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE 76 1.57e-01 -0.093800 0.65300
REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3 59 1.58e-01 -0.106000 0.65300
REACTOME EICOSANOIDS 12 1.58e-01 -0.235000 0.65300
REACTOME RORA ACTIVATES GENE EXPRESSION 17 1.58e-01 0.198000 0.65300
REACTOME REGULATION OF NPAS4 MRNA TRANSLATION 9 1.58e-01 0.272000 0.65300
REACTOME METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS 122 1.61e-01 0.073600 0.65700
REACTOME INTEGRATION OF ENERGY METABOLISM 105 1.61e-01 0.079200 0.65700
REACTOME SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX 15 1.61e-01 0.209000 0.65700
REACTOME GERM LAYER FORMATION AT GASTRULATION 17 1.61e-01 -0.196000 0.65700
REACTOME SIGNALING BY GPCR 673 1.62e-01 0.031600 0.65700
REACTOME NICOTINAMIDE SALVAGING 19 1.62e-01 -0.185000 0.65700
REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR 11 1.63e-01 0.243000 0.65700
REACTOME PI3K AKT SIGNALING IN CANCER 103 1.64e-01 0.079500 0.65700
REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION 160 1.64e-01 0.063700 0.65700
REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3 679 1.65e-01 0.031300 0.65700
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS 6 1.65e-01 -0.327000 0.65700
REACTOME FRUCTOSE METABOLISM 7 1.66e-01 0.302000 0.65700
REACTOME NERVOUS SYSTEM DEVELOPMENT 552 1.66e-01 -0.034500 0.65700
REACTOME DNA METHYLATION 58 1.66e-01 -0.105000 0.65700
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER 28 1.66e-01 -0.151000 0.65700
REACTOME CLEC7A DECTIN 1 SIGNALING 97 1.66e-01 0.081400 0.65700
REACTOME GAB1 SIGNALOSOME 17 1.66e-01 0.194000 0.65700
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1 20 1.67e-01 -0.179000 0.65700
REACTOME TRANSCRIPTIONAL REGULATION BY VENTX 41 1.67e-01 0.125000 0.65700
REACTOME PTEN REGULATION 135 1.68e-01 0.068800 0.65700
REACTOME SIGNALING BY BMP 27 1.68e-01 0.153000 0.65700
REACTOME NGF INDEPENDANT TRKA ACTIVATION 5 1.69e-01 -0.356000 0.65700
REACTOME FIBRONECTIN MATRIX FORMATION 6 1.69e-01 0.325000 0.65700
REACTOME PREGNENOLONE BIOSYNTHESIS 12 1.69e-01 0.229000 0.65700
REACTOME MITOCHONDRIAL CALCIUM ION TRANSPORT 23 1.69e-01 0.166000 0.65700
REACTOME HCMV INFECTION 152 1.70e-01 -0.064500 0.65700
REACTOME SIGNALING BY CSF1 M CSF IN MYELOID CELLS 30 1.70e-01 0.145000 0.65700
REACTOME G ALPHA I SIGNALLING EVENTS 304 1.71e-01 0.045700 0.65800
REACTOME ARACHIDONATE PRODUCTION FROM DAG 5 1.71e-01 0.353000 0.65800
REACTOME TYPE I HEMIDESMOSOME ASSEMBLY 11 1.72e-01 0.238000 0.65900
REACTOME MRNA EDITING C TO U CONVERSION 8 1.72e-01 0.279000 0.65900
REACTOME MINERALOCORTICOID BIOSYNTHESIS 6 1.74e-01 -0.320000 0.66600
REACTOME EARLY PHASE OF HIV LIFE CYCLE 14 1.75e-01 -0.209000 0.66700
REACTOME SIGNALING BY RETINOIC ACID 41 1.76e-01 0.122000 0.66700
REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT 31 1.76e-01 0.140000 0.66800
REACTOME RHOQ GTPASE CYCLE 57 1.77e-01 0.103000 0.66800
REACTOME SYNTHESIS OF 5 EICOSATETRAENOIC ACIDS 9 1.77e-01 0.260000 0.66800
REACTOME EFFECTS OF PIP2 HYDROLYSIS 26 1.78e-01 0.153000 0.66800
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS 9 1.78e-01 0.259000 0.66800
REACTOME TRANSPORT OF RCBL WITHIN THE BODY 8 1.79e-01 0.275000 0.66800
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS 34 1.79e-01 0.133000 0.66800
REACTOME CELLULAR RESPONSE TO HEAT STRESS 99 1.79e-01 -0.078100 0.66800
REACTOME PASSIVE TRANSPORT BY AQUAPORINS 13 1.80e-01 -0.215000 0.66800
REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE 11 1.80e-01 0.234000 0.66800
REACTOME PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS 21 1.81e-01 0.169000 0.67000
REACTOME GLYCEROPHOSPHOLIPID CATABOLISM 7 1.82e-01 0.291000 0.67100
REACTOME TRANSCRIPTIONAL REGULATION BY TP53 351 1.82e-01 0.041400 0.67100
REACTOME CILIUM ASSEMBLY 190 1.82e-01 0.056100 0.67100
REACTOME COMPLEMENT CASCADE 54 1.83e-01 -0.105000 0.67100
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3 11 1.84e-01 -0.232000 0.67100
REACTOME TRNA MODIFICATION IN THE MITOCHONDRION 8 1.84e-01 -0.272000 0.67100
REACTOME GABA B RECEPTOR ACTIVATION 43 1.84e-01 0.117000 0.67100
REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING 25 1.84e-01 -0.153000 0.67200
REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS 43 1.85e-01 0.117000 0.67200
REACTOME HEME DEGRADATION 15 1.86e-01 -0.197000 0.67200
REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS 68 1.86e-01 -0.092800 0.67200
REACTOME SUMOYLATION OF RNA BINDING PROTEINS 47 1.86e-01 -0.111000 0.67200
REACTOME GRB7 EVENTS IN ERBB2 SIGNALING 5 1.88e-01 0.340000 0.67400
REACTOME MULTIFUNCTIONAL ANION EXCHANGERS 9 1.88e-01 0.254000 0.67400
REACTOME RHOA GTPASE CYCLE 142 1.88e-01 0.064000 0.67400
REACTOME REGULATION OF MECP2 EXPRESSION AND ACTIVITY 30 1.88e-01 0.139000 0.67400
REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS 6 1.89e-01 0.310000 0.67400
REACTOME MAPK6 MAPK4 SIGNALING 91 1.90e-01 0.079400 0.67700
REACTOME GLUTAMATE AND GLUTAMINE METABOLISM 13 1.90e-01 0.210000 0.67700
REACTOME INSULIN RECEPTOR SIGNALLING CASCADE 53 1.91e-01 0.104000 0.67800
REACTOME MITOCHONDRIAL BIOGENESIS 87 1.92e-01 0.081000 0.67800
REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET 8 1.93e-01 -0.266000 0.68000
REACTOME RNA POLYMERASE III CHAIN ELONGATION 18 1.93e-01 -0.177000 0.68000
REACTOME MATURATION OF SARS COV 2 SPIKE PROTEIN 35 1.94e-01 0.127000 0.68000
REACTOME COLLAGEN DEGRADATION 61 1.94e-01 -0.096200 0.68100
REACTOME MET ACTIVATES RAP1 AND RAC1 11 1.95e-01 0.225000 0.68200
REACTOME METABOLISM OF STEROIDS 150 1.96e-01 0.061200 0.68200
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES 55 1.96e-01 -0.101000 0.68200
REACTOME ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES 59 1.96e-01 -0.097300 0.68200
REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION 19 1.97e-01 -0.171000 0.68200
REACTOME RHOBTB2 GTPASE CYCLE 22 1.97e-01 0.159000 0.68200
REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS 16 1.98e-01 0.186000 0.68200
REACTOME ERBB2 REGULATES CELL MOTILITY 15 1.98e-01 -0.192000 0.68200
REACTOME REGULATION OF PTEN MRNA TRANSLATION 9 1.99e-01 0.247000 0.68200
REACTOME ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY 10 1.99e-01 0.234000 0.68200
REACTOME DEFECTIVE LFNG CAUSES SCDO3 5 1.99e-01 0.331000 0.68200
REACTOME CITRIC ACID CYCLE TCA CYCLE 21 1.99e-01 0.162000 0.68200
REACTOME CA2 ACTIVATED K CHANNELS 9 2.00e-01 -0.247000 0.68200
REACTOME HDR THROUGH MMEJ ALT NHEJ 12 2.01e-01 -0.213000 0.68400
REACTOME PHASE 4 RESTING MEMBRANE POTENTIAL 19 2.02e-01 -0.169000 0.68400
REACTOME TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS 55 2.02e-01 0.099400 0.68400
REACTOME REGULATION OF TP53 EXPRESSION AND DEGRADATION 37 2.02e-01 0.121000 0.68400
REACTOME FCERI MEDIATED NF KB ACTIVATION 78 2.02e-01 0.083500 0.68400
REACTOME NUCLEAR ENVELOPE BREAKDOWN 52 2.04e-01 -0.102000 0.68700
REACTOME TRANSPORT OF NUCLEOTIDE SUGARS 8 2.05e-01 0.259000 0.68800
REACTOME SIGNALING BY NODAL 20 2.05e-01 0.164000 0.68900
REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION 9 2.07e-01 0.243000 0.69100
REACTOME RAS SIGNALING DOWNSTREAM OF NF1 LOSS OF FUNCTION VARIANTS 7 2.07e-01 -0.275000 0.69100
REACTOME PYRIMIDINE SALVAGE 10 2.07e-01 0.230000 0.69100
REACTOME BETA CATENIN INDEPENDENT WNT SIGNALING 145 2.08e-01 0.060600 0.69200
REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES 77 2.09e-01 -0.082800 0.69400
REACTOME MHC CLASS II ANTIGEN PRESENTATION 121 2.10e-01 0.066000 0.69500
REACTOME REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO 10 2.10e-01 -0.229000 0.69500
REACTOME MITOCHONDRIAL PROTEIN IMPORT 58 2.10e-01 -0.095100 0.69500
REACTOME KERATAN SULFATE KERATIN METABOLISM 34 2.12e-01 0.124000 0.70000
REACTOME SIGNALING BY ERBB4 57 2.14e-01 -0.095200 0.70400
REACTOME ERYTHROPOIETIN ACTIVATES RAS 14 2.15e-01 0.191000 0.70500
REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE 5 2.16e-01 -0.319000 0.70800
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER 28 2.16e-01 -0.135000 0.70800
REACTOME POLO LIKE KINASE MEDIATED EVENTS 16 2.17e-01 -0.178000 0.70900
REACTOME LDL CLEARANCE 19 2.18e-01 0.163000 0.70900
REACTOME INTERLEUKIN 27 SIGNALING 11 2.18e-01 0.214000 0.70900
REACTOME MET ACTIVATES PI3K AKT SIGNALING 6 2.19e-01 0.290000 0.71000
REACTOME NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 22 2.20e-01 0.151000 0.71100
REACTOME COMMON PATHWAY OF FIBRIN CLOT FORMATION 21 2.20e-01 -0.155000 0.71100
REACTOME EPH EPHRIN MEDIATED REPULSION OF CELLS 50 2.22e-01 0.099800 0.71500
REACTOME BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA 5 2.22e-01 -0.315000 0.71500
REACTOME SIGNALING BY KIT IN DISEASE 20 2.23e-01 0.157000 0.71500
REACTOME FORMATION OF LATERAL PLATE MESODERM 5 2.24e-01 -0.314000 0.71500
REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX 14 2.24e-01 0.188000 0.71500
REACTOME RHOC GTPASE CYCLE 71 2.24e-01 0.083400 0.71500
REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL 12 2.25e-01 0.202000 0.71500
REACTOME KERATAN SULFATE BIOSYNTHESIS 28 2.25e-01 0.132000 0.71500
REACTOME REGULATION OF LIPID METABOLISM BY PPARALPHA 115 2.25e-01 0.065400 0.71500
REACTOME SIGNALING BY THE B CELL RECEPTOR BCR 106 2.25e-01 0.068100 0.71500
REACTOME MRNA CAPPING 28 2.27e-01 0.132000 0.71800
REACTOME DNA REPLICATION PRE INITIATION 150 2.28e-01 -0.057000 0.71800
REACTOME REGULATION OF RUNX1 EXPRESSION AND ACTIVITY 17 2.29e-01 0.168000 0.71800
REACTOME SYNTHESIS OF PA 38 2.30e-01 0.113000 0.71800
REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION 84 2.30e-01 -0.075700 0.71800
REACTOME AMINO ACIDS REGULATE MTORC1 53 2.30e-01 0.095300 0.71800
REACTOME PI3K EVENTS IN ERBB4 SIGNALING 10 2.30e-01 -0.219000 0.71800
REACTOME INTERLEUKIN 15 SIGNALING 13 2.31e-01 0.192000 0.71800
REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE 16 2.31e-01 0.173000 0.71800
REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS 29 2.31e-01 0.129000 0.71800
REACTOME HDL ASSEMBLY 8 2.31e-01 0.244000 0.71800
REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF 17 2.33e-01 0.167000 0.72100
REACTOME RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES TREGS 9 2.34e-01 -0.229000 0.72400
REACTOME PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS 8 2.35e-01 0.242000 0.72400
REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING 6 2.36e-01 -0.280000 0.72400
REACTOME UREA CYCLE 9 2.36e-01 0.228000 0.72400
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL 122 2.36e-01 -0.062100 0.72400
REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT 222 2.38e-01 -0.046000 0.72500
REACTOME DEPOLYMERISATION OF THE NUCLEAR LAMINA 14 2.38e-01 0.182000 0.72500
REACTOME SIGNALING BY ALK IN CANCER 53 2.38e-01 0.093600 0.72500
REACTOME ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN 13 2.39e-01 0.189000 0.72500
REACTOME STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES 16 2.39e-01 -0.170000 0.72500
REACTOME GAP JUNCTION TRAFFICKING AND REGULATION 49 2.39e-01 0.097300 0.72500
REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX 57 2.40e-01 0.090100 0.72600
REACTOME REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION 84 2.42e-01 0.073900 0.72600
REACTOME METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION 15 2.42e-01 0.174000 0.72600
REACTOME NONHOMOLOGOUS END JOINING NHEJ 64 2.42e-01 -0.084500 0.72600
REACTOME PROCESSING OF DNA DOUBLE STRAND BREAK ENDS 93 2.43e-01 -0.070100 0.72600
REACTOME CHONDROITIN SULFATE BIOSYNTHESIS 18 2.43e-01 0.159000 0.72600
REACTOME FORMATION OF AXIAL MESODERM 14 2.43e-01 -0.180000 0.72600
REACTOME RAF ACTIVATION 33 2.43e-01 0.117000 0.72600
REACTOME SYNTHESIS OF 15 EICOSATETRAENOIC ACID DERIVATIVES 6 2.44e-01 0.275000 0.72600
REACTOME G ALPHA S SIGNALLING EVENTS 155 2.44e-01 0.054200 0.72600
REACTOME ATORVASTATIN ADME 9 2.45e-01 -0.224000 0.72700
REACTOME ANCHORING FIBRIL FORMATION 13 2.45e-01 -0.186000 0.72900
REACTOME ACYL CHAIN REMODELLING OF PI 17 2.46e-01 -0.163000 0.72900
REACTOME RHO GTPASES ACTIVATE WASPS AND WAVES 34 2.47e-01 0.115000 0.73000
REACTOME RHO GTPASES ACTIVATE NADPH OXIDASES 21 2.47e-01 0.146000 0.73000
REACTOME SIGNALING BY NOTCH 234 2.50e-01 0.043600 0.73500
REACTOME DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B 7 2.50e-01 0.251000 0.73500
REACTOME INTERLEUKIN 17 SIGNALING 66 2.51e-01 0.081800 0.73500
REACTOME RRNA PROCESSING IN THE MITOCHONDRION 9 2.51e-01 -0.221000 0.73500
REACTOME HYALURONAN BIOSYNTHESIS AND EXPORT 5 2.51e-01 0.296000 0.73500
REACTOME APOPTOSIS 173 2.52e-01 0.050400 0.73500
REACTOME SIGNALING BY PDGFR IN DISEASE 20 2.53e-01 0.148000 0.73500
REACTOME METHIONINE SALVAGE PATHWAY 6 2.53e-01 0.270000 0.73500
REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT 15 2.54e-01 -0.170000 0.73500
REACTOME HDACS DEACETYLATE HISTONES 85 2.54e-01 -0.071600 0.73500
REACTOME SARS COV 2 INFECTION 281 2.54e-01 -0.039600 0.73500
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES 49 2.55e-01 0.094100 0.73500
REACTOME RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION 8 2.55e-01 0.232000 0.73500
REACTOME EARLY SARS COV 2 INFECTION EVENTS 34 2.55e-01 0.113000 0.73500
REACTOME SYNDECAN INTERACTIONS 26 2.56e-01 -0.129000 0.73700
REACTOME NUCLEAR EVENTS MEDIATED BY NFE2L2 77 2.57e-01 0.074800 0.73700
REACTOME NEURONAL SYSTEM 388 2.57e-01 -0.033500 0.73800
REACTOME P75NTR REGULATES AXONOGENESIS 9 2.58e-01 -0.218000 0.73800
REACTOME VEGFR2 MEDIATED CELL PROLIFERATION 19 2.60e-01 0.149000 0.74300
REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION 26 2.61e-01 0.127000 0.74300
REACTOME MELANIN BIOSYNTHESIS 5 2.61e-01 -0.290000 0.74300
REACTOME INTERLEUKIN 18 SIGNALING 8 2.62e-01 -0.229000 0.74300
REACTOME TRYPTOPHAN CATABOLISM 14 2.62e-01 -0.173000 0.74400
REACTOME TRAF6 MEDIATED NF KB ACTIVATION 24 2.63e-01 0.132000 0.74400
REACTOME CHYLOMICRON REMODELING 10 2.65e-01 -0.204000 0.74900
REACTOME POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION 27 2.66e-01 -0.124000 0.75000
REACTOME INLA MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS 9 2.66e-01 0.214000 0.75000
REACTOME AMINO ACID CONJUGATION 9 2.69e-01 -0.213000 0.75400
REACTOME SIGNALING BY ERBB2 50 2.69e-01 0.090400 0.75400
REACTOME HUR ELAVL1 BINDS AND STABILIZES MRNA 8 2.69e-01 0.225000 0.75400
REACTOME MET ACTIVATES PTK2 SIGNALING 30 2.70e-01 -0.116000 0.75400
REACTOME FGFR1B LIGAND BINDING AND ACTIVATION 6 2.70e-01 0.260000 0.75400
REACTOME CREB3 FACTORS ACTIVATE GENES 8 2.72e-01 0.224000 0.75700
REACTOME NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 11 2.72e-01 0.191000 0.75700
REACTOME PLASMA LIPOPROTEIN CLEARANCE 37 2.73e-01 0.104000 0.75700
REACTOME CD28 DEPENDENT PI3K AKT SIGNALING 22 2.73e-01 0.135000 0.75700
REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS 21 2.73e-01 -0.138000 0.75700
REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING 30 2.74e-01 0.115000 0.75800
REACTOME SIGNALLING TO P38 VIA RIT AND RIN 5 2.75e-01 -0.282000 0.75800
REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM 23 2.76e-01 -0.131000 0.76000
REACTOME LRR FLII INTERACTING PROTEIN 1 LRRFIP1 ACTIVATES TYPE I IFN PRODUCTION 5 2.78e-01 0.280000 0.76600
REACTOME LAGGING STRAND SYNTHESIS 19 2.80e-01 -0.143000 0.76800
REACTOME ABC TRANSPORTER DISORDERS 76 2.80e-01 -0.071600 0.76800
REACTOME TYROSINE CATABOLISM 5 2.81e-01 0.278000 0.76800
REACTOME CELLULAR RESPONSES TO STIMULI 779 2.82e-01 0.022700 0.76800
REACTOME NFE2L2 REGULATING ANTI OXIDANT DETOXIFICATION ENZYMES 17 2.82e-01 0.151000 0.76800
REACTOME LONG TERM POTENTIATION 22 2.82e-01 -0.132000 0.76800
REACTOME RHO GTPASES ACTIVATE IQGAPS 31 2.82e-01 0.112000 0.76800
REACTOME GROWTH HORMONE RECEPTOR SIGNALING 24 2.83e-01 -0.127000 0.76800
REACTOME ETHANOL OXIDATION 12 2.84e-01 0.179000 0.76900
REACTOME RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS 5 2.85e-01 0.276000 0.77000
REACTOME METABOLISM OF NUCLEOTIDES 94 2.86e-01 0.063700 0.77000
REACTOME BETA OXIDATION OF BUTANOYL COA TO ACETYL COA 5 2.86e-01 0.276000 0.77000
REACTOME INTERLEUKIN 20 FAMILY SIGNALING 25 2.87e-01 0.123000 0.77100
REACTOME TRANSPORT OF FATTY ACIDS 8 2.87e-01 -0.217000 0.77100
REACTOME CYTOPROTECTION BY HMOX1 59 2.89e-01 0.079800 0.77100
REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS 11 2.89e-01 -0.185000 0.77100
REACTOME CELL CYCLE CHECKPOINTS 284 2.89e-01 -0.036600 0.77100
REACTOME PHASE 3 RAPID REPOLARISATION 8 2.89e-01 0.216000 0.77100
REACTOME DISORDERS OF TRANSMEMBRANE TRANSPORTERS 170 2.90e-01 -0.047100 0.77100
REACTOME SIGNALING BY INTERLEUKINS 444 2.90e-01 0.029300 0.77100
REACTOME STAT5 ACTIVATION 7 2.91e-01 0.230000 0.77100
REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE 22 2.91e-01 -0.130000 0.77100
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL 15 2.92e-01 0.157000 0.77100
REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS 93 2.93e-01 -0.063100 0.77100
REACTOME TRIGLYCERIDE CATABOLISM 23 2.93e-01 0.127000 0.77100
REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION 13 2.93e-01 0.168000 0.77100
REACTOME PRC2 METHYLATES HISTONES AND DNA 65 2.94e-01 -0.075200 0.77100
REACTOME INTERFERON SIGNALING 193 2.95e-01 -0.043800 0.77100
REACTOME SYNTHESIS OF PI 5 2.95e-01 0.270000 0.77100
REACTOME CGMP EFFECTS 16 2.95e-01 -0.151000 0.77100
REACTOME INTERLEUKIN 12 FAMILY SIGNALING 53 2.95e-01 0.083100 0.77100
REACTOME LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS 19 2.95e-01 0.139000 0.77100
REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY 51 2.96e-01 0.084600 0.77200
REACTOME P75NTR SIGNALS VIA NF KB 15 2.97e-01 0.156000 0.77200
REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION 23 2.98e-01 -0.125000 0.77500
REACTOME TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX 10 2.99e-01 0.190000 0.77500
REACTOME HYALURONAN METABOLISM 17 2.99e-01 0.145000 0.77500
REACTOME BILE ACID AND BILE SALT METABOLISM 45 3.01e-01 0.089100 0.77900
REACTOME MET ACTIVATES PTPN11 5 3.02e-01 0.267000 0.77900
REACTOME SHC1 EVENTS IN ERBB4 SIGNALING 14 3.03e-01 -0.159000 0.78100
REACTOME GLUTATHIONE CONJUGATION 33 3.03e-01 0.104000 0.78100
REACTOME FOXO MEDIATED TRANSCRIPTION 65 3.04e-01 -0.073700 0.78100
REACTOME G2 M CHECKPOINTS 162 3.06e-01 -0.046600 0.78100
REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION 68 3.06e-01 -0.071700 0.78100
REACTOME FORMATION OF PARAXIAL MESODERM 22 3.07e-01 0.126000 0.78100
REACTOME COLLAGEN FORMATION 88 3.07e-01 -0.063000 0.78100
REACTOME SIGNALING BY NTRK2 TRKB 25 3.07e-01 -0.118000 0.78100
REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS 66 3.08e-01 -0.072600 0.78100
REACTOME HOST INTERACTIONS OF HIV FACTORS 127 3.09e-01 -0.052300 0.78100
REACTOME ASSEMBLY OF THE HIV VIRION 16 3.09e-01 0.147000 0.78100
REACTOME INTERLEUKIN 1 PROCESSING 9 3.09e-01 0.196000 0.78100
REACTOME ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY 10 3.09e-01 0.186000 0.78100
REACTOME CLATHRIN MEDIATED ENDOCYTOSIS 139 3.09e-01 0.050000 0.78100
REACTOME GP1B IX V ACTIVATION SIGNALLING 11 3.11e-01 0.177000 0.78400
REACTOME PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS 7 3.11e-01 -0.221000 0.78400
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX3 94 3.13e-01 0.060200 0.78700
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST 18 3.14e-01 0.137000 0.78700
REACTOME SIGNALING BY ACTIVIN 15 3.16e-01 0.150000 0.79100
REACTOME HEME BIOSYNTHESIS 13 3.16e-01 -0.161000 0.79100
REACTOME CHAPERONE MEDIATED AUTOPHAGY 20 3.16e-01 -0.129000 0.79100
REACTOME MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION 15 3.17e-01 0.149000 0.79200
REACTOME ROBO RECEPTORS BIND AKAP5 9 3.19e-01 0.192000 0.79500
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION 36 3.20e-01 0.095900 0.79500
REACTOME RHO GTPASES ACTIVATE ROCKS 19 3.20e-01 -0.132000 0.79600
REACTOME ADRENOCEPTORS 9 3.21e-01 -0.191000 0.79600
REACTOME PROTEIN FOLDING 96 3.22e-01 0.058500 0.79700
REACTOME MITOTIC G2 G2 M PHASES 194 3.22e-01 0.041200 0.79700
REACTOME BUDDING AND MATURATION OF HIV VIRION 28 3.24e-01 0.108000 0.79800
REACTOME CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA 63 3.24e-01 -0.071800 0.79800
REACTOME G ALPHA Z SIGNALLING EVENTS 48 3.24e-01 0.082200 0.79800
REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX 13 3.25e-01 -0.158000 0.79800
REACTOME TRIGLYCERIDE METABOLISM 35 3.27e-01 0.095800 0.80200
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD4 15 3.28e-01 0.146000 0.80300
REACTOME PLASMA LIPOPROTEIN REMODELING 33 3.29e-01 -0.098200 0.80300
REACTOME HEDGEHOG OFF STATE 111 3.29e-01 0.053600 0.80300
REACTOME HIV LIFE CYCLE 145 3.29e-01 -0.047000 0.80300
REACTOME IRAK1 RECRUITS IKK COMPLEX 12 3.30e-01 0.162000 0.80400
REACTOME BICARBONATE TRANSPORTERS 10 3.30e-01 0.178000 0.80400
REACTOME MTOR SIGNALLING 40 3.32e-01 0.088700 0.80600
REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION 62 3.33e-01 -0.071100 0.80700
REACTOME DISEASES OF CARBOHYDRATE METABOLISM 31 3.33e-01 0.100000 0.80700
REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS 83 3.34e-01 0.061300 0.80700
REACTOME HEDGEHOG LIGAND BIOGENESIS 64 3.35e-01 -0.069700 0.80700
REACTOME RHOJ GTPASE CYCLE 51 3.35e-01 0.078100 0.80700
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST 14 3.36e-01 0.149000 0.80700
REACTOME HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR IN THE PRESENCE OF LIGAND 55 3.36e-01 0.075000 0.80700
REACTOME DNA REPLICATION INITIATION 7 3.36e-01 -0.210000 0.80700
REACTOME LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX 5 3.37e-01 0.248000 0.80700
REACTOME INTERLEUKIN RECEPTOR SHC SIGNALING 24 3.37e-01 -0.113000 0.80700
REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK 17 3.37e-01 0.134000 0.80700
REACTOME CD163 MEDIATING AN ANTI INFLAMMATORY RESPONSE 9 3.39e-01 0.184000 0.80700
REACTOME INWARDLY RECTIFYING K CHANNELS 35 3.40e-01 0.093200 0.80700
REACTOME ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT 23 3.40e-01 0.115000 0.80700
REACTOME NOD1 2 SIGNALING PATHWAY 33 3.40e-01 0.095900 0.80700
REACTOME RUNX3 REGULATES WNT SIGNALING 8 3.41e-01 -0.195000 0.80700
REACTOME ION HOMEOSTASIS 52 3.43e-01 0.076100 0.80700
REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA 11 3.43e-01 0.165000 0.80700
REACTOME INITIAL TRIGGERING OF COMPLEMENT 21 3.43e-01 -0.120000 0.80700
REACTOME NEGATIVE REGULATION OF ACTIVITY OF TFAP2 AP 2 FAMILY TRANSCRIPTION FACTORS 10 3.44e-01 0.173000 0.80700
REACTOME CHREBP ACTIVATES METABOLIC GENE EXPRESSION 8 3.44e-01 0.193000 0.80700
REACTOME DIGESTION 17 3.44e-01 -0.133000 0.80700
REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS 53 3.45e-01 0.075000 0.80700
REACTOME PROLACTIN RECEPTOR SIGNALING 15 3.45e-01 -0.141000 0.80700
REACTOME SIGNAL TRANSDUCTION BY L1 20 3.45e-01 0.122000 0.80700
REACTOME UNWINDING OF DNA 12 3.45e-01 0.157000 0.80700
REACTOME ARACHIDONIC ACID METABOLISM 57 3.46e-01 0.072200 0.80700
REACTOME PECAM1 INTERACTIONS 12 3.46e-01 -0.157000 0.80700
REACTOME PYRUVATE METABOLISM 29 3.48e-01 0.101000 0.80900
REACTOME AMINE LIGAND BINDING RECEPTORS 40 3.49e-01 -0.085600 0.80900
REACTOME ARMS MEDIATED ACTIVATION 7 3.50e-01 -0.204000 0.80900
REACTOME UBIQUINOL BIOSYNTHESIS 8 3.50e-01 -0.191000 0.80900
REACTOME BETA OXIDATION OF PRISTANOYL COA 9 3.50e-01 0.180000 0.80900
REACTOME TRANSCRIPTIONAL REGULATION BY E2F6 32 3.51e-01 0.095300 0.80900
REACTOME CELL CYCLE 666 3.51e-01 -0.021200 0.80900
REACTOME ORGANIC CATION TRANSPORT 10 3.52e-01 -0.170000 0.80900
REACTOME COBALAMIN CBL METABOLISM 7 3.53e-01 -0.203000 0.80900
REACTOME RNA POLYMERASE I TRANSCRIPTION 102 3.53e-01 -0.053200 0.80900
REACTOME SEMA3A PAK DEPENDENT AXON REPULSION 14 3.53e-01 0.143000 0.80900
REACTOME RSK ACTIVATION 5 3.53e-01 0.240000 0.80900
REACTOME PROTEIN LOCALIZATION 153 3.53e-01 -0.043500 0.80900
REACTOME SIGNALING BY NOTCH4 80 3.59e-01 0.059400 0.81900
REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI 17 3.59e-01 -0.128000 0.81900
REACTOME UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION 19 3.60e-01 -0.121000 0.81900
REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION 6 3.60e-01 0.216000 0.81900
REACTOME FREE FATTY ACID RECEPTORS 5 3.61e-01 0.236000 0.81900
REACTOME STRIATED MUSCLE CONTRACTION 35 3.61e-01 0.089200 0.81900
REACTOME TIGHT JUNCTION INTERACTIONS 29 3.61e-01 0.097900 0.81900
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION 81 3.61e-01 0.058600 0.81900
REACTOME SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS 43 3.62e-01 0.080300 0.81900
REACTOME FORMATION OF THE CORNIFIED ENVELOPE 125 3.63e-01 -0.047100 0.82000
REACTOME NICOTINATE METABOLISM 31 3.63e-01 -0.094300 0.82000
REACTOME DEX H BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION 7 3.64e-01 -0.198000 0.82100
REACTOME DEFECTIVE CHST3 CAUSES SEDCJD 7 3.66e-01 -0.197000 0.82300
REACTOME INTERFERON ALPHA BETA SIGNALING 70 3.66e-01 -0.062400 0.82300
REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION 89 3.67e-01 -0.055300 0.82400
REACTOME CHYLOMICRON CLEARANCE 5 3.70e-01 0.232000 0.82900
REACTOME DEFECTIVE CHST6 CAUSES MCDC1 8 3.70e-01 -0.183000 0.82900
REACTOME PARASITE INFECTION 57 3.73e-01 0.068300 0.83200
REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES 27 3.74e-01 0.098800 0.83400
REACTOME NUCLEOTIDE BIOSYNTHESIS 14 3.76e-01 -0.137000 0.83800
REACTOME LATE SARS COV 2 INFECTION EVENTS 67 3.76e-01 0.062500 0.83800
REACTOME SYNTHESIS OF DOLICHYL PHOSPHATE 6 3.78e-01 0.208000 0.83800
REACTOME ACTIVATION OF RAS IN B CELLS 5 3.78e-01 -0.228000 0.83800
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING 5 3.79e-01 -0.227000 0.83800
REACTOME TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX 14 3.79e-01 0.136000 0.83800
REACTOME REGULATION OF GENE EXPRESSION IN ENDOCRINE COMMITTED NEUROG3 PROGENITOR CELLS 5 3.80e-01 -0.227000 0.83800
REACTOME SODIUM CALCIUM EXCHANGERS 11 3.80e-01 0.153000 0.83800
REACTOME SARS COV 2 MODULATES AUTOPHAGY 11 3.81e-01 0.153000 0.83800
REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION 8 3.82e-01 -0.179000 0.83800
REACTOME METABOLISM OF VITAMINS AND COFACTORS 185 3.82e-01 0.037300 0.83800
REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 22 3.82e-01 0.108000 0.83800
REACTOME DOWNREGULATION OF ERBB2 SIGNALING 29 3.83e-01 0.093600 0.83800
REACTOME DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING 61 3.83e-01 0.064600 0.83800
REACTOME HS GAG BIOSYNTHESIS 28 3.84e-01 0.095100 0.83800
REACTOME POTASSIUM CHANNELS 102 3.85e-01 -0.049800 0.84000
REACTOME NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 25 3.86e-01 0.100000 0.84100
REACTOME BETA CATENIN PHOSPHORYLATION CASCADE 16 3.87e-01 0.125000 0.84200
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE GIP 12 3.87e-01 -0.144000 0.84200
REACTOME PENTOSE PHOSPHATE PATHWAY 12 3.88e-01 0.144000 0.84300
REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL 14 3.89e-01 0.133000 0.84300
REACTOME BINDING OF TCF LEF CTNNB1 TO TARGET GENE PROMOTERS 8 3.90e-01 -0.176000 0.84300
REACTOME ACETYLCHOLINE REGULATES INSULIN SECRETION 10 3.90e-01 0.157000 0.84300
REACTOME IKBA VARIANT LEADS TO EDA ID 6 3.91e-01 0.202000 0.84300
REACTOME PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING 11 3.91e-01 -0.149000 0.84300
REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE 15 3.91e-01 0.128000 0.84300
REACTOME GPCR LIGAND BINDING 444 3.92e-01 -0.023700 0.84300
REACTOME UPTAKE AND FUNCTION OF ANTHRAX TOXINS 11 3.92e-01 0.149000 0.84300
REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING 29 3.94e-01 0.091400 0.84600
REACTOME VITAMIN B2 RIBOFLAVIN METABOLISM 7 3.96e-01 0.185000 0.84800
REACTOME REGULATION OF INSULIN SECRETION 77 3.96e-01 0.055900 0.84900
REACTOME HDMS DEMETHYLATE HISTONES 40 3.99e-01 -0.077100 0.85100
REACTOME TBC RABGAPS 40 3.99e-01 0.077100 0.85100
REACTOME ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA 9 3.99e-01 0.162000 0.85100
REACTOME ENOS ACTIVATION 11 4.00e-01 0.146000 0.85200
REACTOME COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC 98 4.02e-01 -0.049000 0.85400
REACTOME SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS 16 4.02e-01 0.121000 0.85400
REACTOME BIOTIN TRANSPORT AND METABOLISM 10 4.03e-01 0.153000 0.85500
REACTOME DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE 17 4.05e-01 -0.117000 0.85700
REACTOME RNA POLYMERASE III TRANSCRIPTION 41 4.06e-01 -0.075100 0.85700
REACTOME GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION 30 4.06e-01 0.087700 0.85700
REACTOME UPTAKE OF DIETARY COBALAMINS INTO ENTEROCYTES 9 4.06e-01 -0.160000 0.85700
REACTOME GRB2 EVENTS IN ERBB2 SIGNALING 16 4.06e-01 -0.120000 0.85700
REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY 25 4.08e-01 -0.095700 0.85800
REACTOME NRCAM INTERACTIONS 6 4.09e-01 -0.195000 0.86000
REACTOME CREATION OF C4 AND C2 ACTIVATORS 14 4.09e-01 -0.127000 0.86000
REACTOME FATTY ACIDS 15 4.11e-01 0.123000 0.86100
REACTOME G0 AND EARLY G1 27 4.13e-01 0.091100 0.86100
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH RAS 9 4.14e-01 -0.157000 0.86100
REACTOME BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS 10 4.14e-01 -0.149000 0.86100
REACTOME FRUCTOSE CATABOLISM 5 4.14e-01 0.211000 0.86100
REACTOME COENZYME A BIOSYNTHESIS 8 4.14e-01 0.167000 0.86100
REACTOME RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY 14 4.14e-01 -0.126000 0.86100
REACTOME RHOF GTPASE CYCLE 40 4.14e-01 0.074600 0.86100
REACTOME ONCOGENE INDUCED SENESCENCE 35 4.16e-01 0.079400 0.86400
REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS 9 4.19e-01 -0.156000 0.86800
REACTOME MITOCHONDRIAL UNCOUPLING 5 4.19e-01 -0.209000 0.86800
REACTOME DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS 15 4.20e-01 0.120000 0.86800
REACTOME ABACAVIR ADME 9 4.21e-01 -0.155000 0.86800
REACTOME GABA RECEPTOR ACTIVATION 57 4.21e-01 0.061600 0.86800
REACTOME CELL CELL JUNCTION ORGANIZATION 64 4.22e-01 0.058100 0.86800
REACTOME THE NLRP3 INFLAMMASOME 16 4.22e-01 0.116000 0.86800
REACTOME L1CAM INTERACTIONS 112 4.23e-01 0.043800 0.86900
REACTOME RIPK1 MEDIATED REGULATED NECROSIS 30 4.25e-01 -0.084200 0.87000
REACTOME FLT3 SIGNALING THROUGH SRC FAMILY KINASES 6 4.26e-01 -0.188000 0.87000
REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS 14 4.26e-01 0.123000 0.87000
REACTOME LGI ADAM INTERACTIONS 14 4.27e-01 0.123000 0.87000
REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE 17 4.27e-01 -0.111000 0.87000
REACTOME SARS COV 2 TARGETS PDZ PROTEINS IN CELL CELL JUNCTION 5 4.27e-01 0.205000 0.87000
REACTOME INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE 20 4.29e-01 0.102000 0.87000
REACTOME SIGNALING BY MRAS COMPLEX MUTANTS 7 4.29e-01 -0.172000 0.87000
REACTOME MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS 7 4.31e-01 -0.172000 0.87000
REACTOME O LINKED GLYCOSYLATION 109 4.31e-01 0.043600 0.87000
REACTOME HSF1 DEPENDENT TRANSACTIVATION 37 4.32e-01 0.074600 0.87000
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL 14 4.33e-01 0.121000 0.87000
REACTOME COPII MEDIATED VESICLE TRANSPORT 66 4.33e-01 0.055800 0.87000
REACTOME BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA 6 4.33e-01 -0.185000 0.87000
REACTOME DECTIN 2 FAMILY 26 4.33e-01 0.088800 0.87000
REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS 113 4.34e-01 -0.042600 0.87000
REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY 23 4.34e-01 0.094200 0.87000
REACTOME SIGNALING BY NOTCH1 T 7 9 NOTCH1 M1580 K2555 TRANSLOCATION MUTANT 7 4.34e-01 0.171000 0.87000
REACTOME DNA REPLICATION 178 4.35e-01 -0.033900 0.87000
REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III 31 4.36e-01 0.080900 0.87000
REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 98 4.36e-01 -0.045500 0.87000
REACTOME ERK MAPK TARGETS 20 4.36e-01 0.101000 0.87000
REACTOME REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS 7 4.37e-01 0.170000 0.87000
REACTOME ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY 5 4.37e-01 -0.201000 0.87000
REACTOME SIGNALING BY MAPK MUTANTS 6 4.38e-01 0.183000 0.87000
REACTOME FANCONI ANEMIA PATHWAY 35 4.38e-01 0.075700 0.87000
REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE 30 4.39e-01 0.081600 0.87000
REACTOME PROCESSING OF INTRONLESS PRE MRNAS 19 4.40e-01 0.102000 0.87000
REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER 77 4.41e-01 0.050800 0.87000
REACTOME EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION 27 4.41e-01 0.085700 0.87000
REACTOME HDL REMODELING 10 4.41e-01 0.141000 0.87000
REACTOME CROSSLINKING OF COLLAGEN FIBRILS 16 4.41e-01 -0.111000 0.87000
REACTOME NEUROFASCIN INTERACTIONS 6 4.42e-01 -0.181000 0.87000
REACTOME HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS 7 4.43e-01 0.167000 0.87000
REACTOME ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS 10 4.44e-01 -0.140000 0.87000
REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE 17 4.44e-01 -0.107000 0.87000
REACTOME COHESIN LOADING ONTO CHROMATIN 8 4.44e-01 -0.156000 0.87000
REACTOME FLT3 SIGNALING BY CBL MUTANTS 7 4.45e-01 0.167000 0.87000
REACTOME SIGNALING BY FGFR2 IIIA TM 19 4.45e-01 0.101000 0.87000
REACTOME ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM 12 4.45e-01 0.127000 0.87000
REACTOME PEPTIDE LIGAND BINDING RECEPTORS 188 4.45e-01 -0.032300 0.87000
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH RAS 8 4.46e-01 -0.156000 0.87000
REACTOME INTRAFLAGELLAR TRANSPORT 50 4.47e-01 0.062200 0.87100
REACTOME SYNTHESIS OF LIPOXINS LX 6 4.47e-01 0.179000 0.87100
REACTOME MAPK FAMILY SIGNALING CASCADES 314 4.48e-01 0.024900 0.87200
REACTOME DEGRADATION OF GLI1 BY THE PROTEASOME 59 4.50e-01 0.056900 0.87300
REACTOME REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS 15 4.50e-01 0.113000 0.87300
REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION 20 4.50e-01 0.097500 0.87300
REACTOME MYOCLONIC EPILEPSY OF LAFORA 9 4.51e-01 0.145000 0.87300
REACTOME IRF3 MEDIATED INDUCTION OF TYPE I IFN 13 4.51e-01 -0.121000 0.87300
REACTOME ALPHA DEFENSINS 6 4.52e-01 -0.177000 0.87300
REACTOME NTRK2 ACTIVATES RAC1 5 4.53e-01 -0.194000 0.87400
REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND 14 4.53e-01 -0.116000 0.87400
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES 16 4.55e-01 -0.108000 0.87600
REACTOME AUTOPHAGY 144 4.57e-01 0.035900 0.87800
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX2 117 4.57e-01 0.039800 0.87800
REACTOME CALCITONIN LIKE LIGAND RECEPTORS 10 4.59e-01 -0.135000 0.87900
REACTOME FREE FATTY ACIDS REGULATE INSULIN SECRETION 10 4.60e-01 0.135000 0.87900
REACTOME METABOLISM OF INGESTED SEMET SEC MESEC INTO H2SE 7 4.60e-01 0.161000 0.87900
REACTOME REGULATION OF RAS BY GAPS 66 4.60e-01 -0.052500 0.87900
REACTOME APEX1 INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY 7 4.61e-01 0.161000 0.87900
REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM 50 4.62e-01 0.060100 0.87900
REACTOME SIGNALING BY HEDGEHOG 148 4.63e-01 0.034900 0.87900
REACTOME HIV TRANSCRIPTION ELONGATION 42 4.63e-01 0.065400 0.87900
REACTOME EPITHELIAL MESENCHYMAL TRANSITION EMT DURING GASTRULATION 7 4.63e-01 0.160000 0.87900
REACTOME HORMONE LIGAND BINDING RECEPTORS 12 4.64e-01 0.122000 0.87900
REACTOME REGULATION OF TP53 ACTIVITY 156 4.64e-01 0.034000 0.87900
REACTOME RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION 22 4.64e-01 0.090100 0.88000
REACTOME RUNX3 REGULATES YAP1 MEDIATED TRANSCRIPTION 8 4.66e-01 -0.149000 0.88100
REACTOME PTK6 PROMOTES HIF1A STABILIZATION 6 4.66e-01 0.172000 0.88100
REACTOME FC EPSILON RECEPTOR FCERI SIGNALING 127 4.67e-01 0.037300 0.88100
REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION 11 4.67e-01 0.127000 0.88100
REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES 12 4.69e-01 0.121000 0.88300
REACTOME AMYLOID FIBER FORMATION 102 4.70e-01 -0.041400 0.88400
REACTOME RESPONSE TO METAL IONS 14 4.71e-01 -0.111000 0.88500
REACTOME SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL 25 4.72e-01 0.083200 0.88500
REACTOME FGFR2B LIGAND BINDING AND ACTIVATION 10 4.73e-01 0.131000 0.88600
REACTOME SIGNALING BY NTRK3 TRKC 17 4.74e-01 -0.100000 0.88600
REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE 19 4.74e-01 -0.094900 0.88600
REACTOME SMAC XIAP REGULATED APOPTOTIC RESPONSE 7 4.74e-01 -0.156000 0.88600
REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH 62 4.75e-01 -0.052500 0.88600
REACTOME GLYCOGEN SYNTHESIS 13 4.76e-01 0.114000 0.88700
REACTOME TOXICITY OF BOTULINUM TOXIN TYPE D BOTD 5 4.77e-01 -0.184000 0.88700
REACTOME MISCELLANEOUS TRANSPORT AND BINDING EVENTS 24 4.78e-01 0.083600 0.88700
REACTOME EXTENSION OF TELOMERES 49 4.78e-01 -0.058600 0.88700
REACTOME NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10 12 4.78e-01 0.118000 0.88700
REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE 21 4.79e-01 -0.089200 0.88800
REACTOME REGULATION OF KIT SIGNALING 16 4.80e-01 0.102000 0.88800
REACTOME SIGNALING BY HIPPO 19 4.81e-01 0.093400 0.88800
REACTOME ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING 23 4.81e-01 0.084900 0.88800
REACTOME REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION 9 4.83e-01 0.135000 0.89000
REACTOME NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION 20 4.84e-01 -0.090500 0.89000
REACTOME SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS 12 4.84e-01 0.117000 0.89000
REACTOME VLDLR INTERNALISATION AND DEGRADATION 16 4.85e-01 0.101000 0.89000
REACTOME NECTIN NECL TRANS HETERODIMERIZATION 7 4.85e-01 0.152000 0.89000
REACTOME REGULATION OF PTEN STABILITY AND ACTIVITY 67 4.85e-01 0.049300 0.89000
REACTOME SCAVENGING OF HEME FROM PLASMA 13 4.86e-01 0.112000 0.89000
REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS 6 4.87e-01 0.164000 0.89100
REACTOME LIGAND RECEPTOR INTERACTIONS 8 4.88e-01 -0.142000 0.89100
REACTOME TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION 5 4.89e-01 -0.179000 0.89100
REACTOME METABOLISM OF FOLATE AND PTERINES 17 4.89e-01 0.097000 0.89100
REACTOME REGULATION OF IFNA IFNB SIGNALING 23 4.89e-01 -0.083300 0.89100
REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY 72 4.91e-01 0.047000 0.89100
REACTOME DEUBIQUITINATION 260 4.91e-01 0.024800 0.89100
REACTOME DIGESTION OF DIETARY CARBOHYDRATE 6 4.92e-01 -0.162000 0.89100
REACTOME HOMOLOGY DIRECTED REPAIR 132 4.92e-01 -0.034600 0.89100
REACTOME RNA POLYMERASE II TRANSCRIPTION 1336 4.92e-01 0.011200 0.89100
REACTOME SYNTHESIS OF DIPHTHAMIDE EEF2 8 4.92e-01 0.140000 0.89100
REACTOME REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR 11 4.93e-01 0.119000 0.89200
REACTOME FLT3 SIGNALING 38 4.97e-01 0.063700 0.89700
REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS 30 5.00e-01 0.071200 0.90200
REACTOME NEGATIVE REGULATION OF MAPK PATHWAY 41 5.02e-01 0.060600 0.90400
REACTOME CYP2E1 REACTIONS 10 5.03e-01 0.122000 0.90500
REACTOME INTEGRATION OF PROVIRUS 9 5.04e-01 -0.129000 0.90500
REACTOME ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA 15 5.04e-01 0.099700 0.90500
REACTOME SIGNALING BY FLT3 FUSION PROTEINS 19 5.05e-01 0.088300 0.90600
REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING 13 5.06e-01 0.107000 0.90600
REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES 29 5.08e-01 0.071100 0.90700
REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS 38 5.08e-01 -0.062100 0.90700
REACTOME DIGESTION AND ABSORPTION 22 5.08e-01 -0.081500 0.90700
REACTOME ORGANIC ANION TRANSPORT 5 5.09e-01 -0.170000 0.90900
REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS 101 5.10e-01 0.037900 0.90900
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES 43 5.11e-01 0.058000 0.90900
REACTOME DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15 8 5.12e-01 -0.134000 0.91000
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS 7 5.13e-01 0.143000 0.91000
REACTOME DEFECTS IN BIOTIN BTN METABOLISM 8 5.14e-01 0.133000 0.91000
REACTOME MITOCHONDRIAL TRNA AMINOACYLATION 20 5.14e-01 0.084200 0.91000
REACTOME M PHASE 398 5.14e-01 -0.019000 0.91000
REACTOME CARGO CONCENTRATION IN THE ER 32 5.15e-01 0.066600 0.91000
REACTOME ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING 9 5.15e-01 -0.125000 0.91000
REACTOME RESOLUTION OF SISTER CHROMATID COHESION 120 5.19e-01 -0.034100 0.91100
REACTOME MODULATION BY MTB OF HOST IMMUNE SYSTEM 6 5.20e-01 -0.152000 0.91100
REACTOME CHL1 INTERACTIONS 9 5.21e-01 -0.124000 0.91100
REACTOME CS DS DEGRADATION 12 5.21e-01 -0.107000 0.91100
REACTOME INDUCTION OF CELL CELL FUSION 12 5.22e-01 -0.107000 0.91100
REACTOME COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING 32 5.23e-01 -0.065200 0.91100
REACTOME RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS 9 5.23e-01 -0.123000 0.91100
REACTOME PRE NOTCH EXPRESSION AND PROCESSING 112 5.24e-01 0.034900 0.91100
REACTOME RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR 19 5.24e-01 -0.084500 0.91100
REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS 5 5.24e-01 -0.164000 0.91100
REACTOME SUMOYLATION OF IMMUNE RESPONSE PROTEINS 10 5.24e-01 0.116000 0.91100
REACTOME METABOLISM OF STEROID HORMONES 35 5.25e-01 -0.062100 0.91100
REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC 26 5.25e-01 -0.072100 0.91100
REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS 45 5.25e-01 0.054800 0.91100
REACTOME SENSING OF DNA DOUBLE STRAND BREAKS 6 5.25e-01 -0.150000 0.91100
REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES 37 5.25e-01 -0.060300 0.91100
REACTOME SIGNALING BY TGFB FAMILY MEMBERS 119 5.26e-01 0.033700 0.91100
REACTOME SYNAPTIC ADHESION LIKE MOLECULES 19 5.26e-01 -0.083900 0.91100
REACTOME NEGATIVE REGULATION OF FLT3 15 5.27e-01 0.094400 0.91100
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS 15 5.27e-01 -0.094400 0.91100
REACTOME FATTY ACIDS BOUND TO GPR40 FFAR1 REGULATE INSULIN SECRETION 8 5.28e-01 0.129000 0.91100
REACTOME NUCLEOTIDE EXCISION REPAIR 107 5.29e-01 -0.035300 0.91100
REACTOME SODIUM COUPLED PHOSPHATE COTRANSPORTERS 5 5.30e-01 0.162000 0.91100
REACTOME PINK1 PRKN MEDIATED MITOPHAGY 22 5.30e-01 -0.077400 0.91100
REACTOME KSRP KHSRP BINDS AND DESTABILIZES MRNA 17 5.30e-01 0.087900 0.91100
REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE 17 5.31e-01 -0.087700 0.91100
REACTOME CONDENSATION OF PROMETAPHASE CHROMOSOMES 11 5.31e-01 -0.109000 0.91100
REACTOME INTERLEUKIN 7 SIGNALING 31 5.32e-01 0.064900 0.91100
REACTOME REGULATION OF NPAS4 GENE TRANSCRIPTION 5 5.32e-01 0.161000 0.91100
REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE 24 5.33e-01 -0.073500 0.91100
REACTOME TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES 61 5.33e-01 0.046100 0.91100
REACTOME SIGNALING BY ERBB2 IN CANCER 26 5.33e-01 -0.070600 0.91100
REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING 45 5.36e-01 -0.053400 0.91200
REACTOME SEPARATION OF SISTER CHROMATIDS 184 5.37e-01 -0.026400 0.91200
REACTOME NETRIN MEDIATED REPULSION SIGNALS 8 5.37e-01 -0.126000 0.91200
REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION 32 5.37e-01 0.063000 0.91200
REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS 16 5.37e-01 0.089100 0.91200
REACTOME CLEC7A INFLAMMASOME PATHWAY 6 5.38e-01 0.145000 0.91200
REACTOME 2 LTR CIRCLE FORMATION 7 5.38e-01 -0.134000 0.91200
REACTOME MITOTIC SPINDLE CHECKPOINT 109 5.38e-01 -0.034100 0.91200
REACTOME TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7 12 5.39e-01 -0.102000 0.91300
REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX 31 5.41e-01 -0.063500 0.91300
REACTOME MICRORNA MIRNA BIOGENESIS 25 5.41e-01 0.070600 0.91300
REACTOME MTORC1 MEDIATED SIGNALLING 23 5.42e-01 0.073500 0.91300
REACTOME MITOTIC METAPHASE AND ANAPHASE 228 5.42e-01 -0.023400 0.91300
REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS 35 5.42e-01 0.059500 0.91300
REACTOME SUPPRESSION OF APOPTOSIS 7 5.43e-01 -0.133000 0.91300
REACTOME GAP JUNCTION ASSEMBLY 36 5.44e-01 0.058400 0.91300
REACTOME SOS MEDIATED SIGNALLING 7 5.45e-01 0.132000 0.91300
REACTOME DNA DAMAGE REVERSAL 8 5.45e-01 0.124000 0.91300
REACTOME DNA DOUBLE STRAND BREAK RESPONSE 74 5.46e-01 -0.040600 0.91300
REACTOME CARNITINE METABOLISM 13 5.46e-01 0.096800 0.91300
REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION 35 5.46e-01 0.059000 0.91300
REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS 111 5.48e-01 -0.033000 0.91500
REACTOME ZINC TRANSPORTERS 15 5.49e-01 0.089400 0.91600
REACTOME DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX 83 5.50e-01 0.038000 0.91600
REACTOME LINOLEIC ACID LA METABOLISM 7 5.51e-01 0.130000 0.91700
REACTOME ALPHA OXIDATION OF PHYTANATE 6 5.51e-01 0.141000 0.91700
REACTOME UPTAKE AND ACTIONS OF BACTERIAL TOXINS 28 5.51e-01 0.065000 0.91700
REACTOME G1 S SPECIFIC TRANSCRIPTION 28 5.53e-01 0.064800 0.91700
REACTOME NUCLEAR SIGNALING BY ERBB4 32 5.54e-01 -0.060500 0.91700
REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB 5 5.54e-01 0.153000 0.91700
REACTOME MITOTIC PROMETAPHASE 194 5.54e-01 0.024600 0.91700
REACTOME NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION 193 5.55e-01 0.024700 0.91700
REACTOME PTK6 REGULATES CELL CYCLE 6 5.55e-01 0.139000 0.91700
REACTOME KILLING MECHANISMS 11 5.56e-01 -0.103000 0.91700
REACTOME KERATAN SULFATE DEGRADATION 13 5.56e-01 -0.094200 0.91700
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM 688 5.57e-01 0.013100 0.91700
REACTOME SEROTONIN NEUROTRANSMITTER RELEASE CYCLE 17 5.58e-01 -0.082100 0.91700
REACTOME OTHER INTERLEUKIN SIGNALING 24 5.58e-01 0.069000 0.91700
REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON 17 5.58e-01 0.082000 0.91700
REACTOME RHOT1 GTPASE CYCLE 5 5.59e-01 0.151000 0.91700
REACTOME PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE 74 5.60e-01 0.039200 0.91700
REACTOME TERMINAL PATHWAY OF COMPLEMENT 8 5.60e-01 -0.119000 0.91700
REACTOME FGFR2 ALTERNATIVE SPLICING 27 5.60e-01 0.064700 0.91700
REACTOME DEFECTIVE CHSY1 CAUSES TPBS 7 5.62e-01 -0.127000 0.91700
REACTOME NEUROTOXICITY OF CLOSTRIDIUM TOXINS 10 5.62e-01 -0.106000 0.91700
REACTOME SULFUR AMINO ACID METABOLISM 27 5.62e-01 0.064500 0.91700
REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS 8 5.65e-01 0.118000 0.91900
REACTOME DOWNSTREAM SIGNAL TRANSDUCTION 29 5.66e-01 0.061600 0.91900
REACTOME RNA POLYMERASE III TRANSCRIPTION TERMINATION 23 5.66e-01 -0.069100 0.91900
REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS 9 5.66e-01 0.110000 0.91900
REACTOME RNA POLYMERASE II PRE TRANSCRIPTION EVENTS 77 5.67e-01 0.037800 0.91900
REACTOME SIGNALING BY FLT3 ITD AND TKD MUTANTS 16 5.67e-01 -0.082700 0.91900
REACTOME INTERLEUKIN 12 SIGNALING 43 5.68e-01 0.050300 0.92000
REACTOME INTERLEUKIN 6 SIGNALING 11 5.69e-01 0.099200 0.92100
REACTOME HDL CLEARANCE 5 5.70e-01 0.147000 0.92100
REACTOME REGULATION OF PTEN GENE TRANSCRIPTION 59 5.70e-01 0.042700 0.92100
REACTOME FRS MEDIATED FGFR4 SIGNALING 21 5.72e-01 -0.071200 0.92100
REACTOME SIGNALING BY EGFR IN CANCER 25 5.73e-01 0.065100 0.92100
REACTOME PI5P REGULATES TP53 ACETYLATION 9 5.74e-01 0.108000 0.92100
REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC 198 5.75e-01 0.023100 0.92100
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR4 26 5.75e-01 -0.063500 0.92100
REACTOME DEFECTIVE B4GALT1 CAUSES B4GALT1 CDG CDG 2D 8 5.76e-01 -0.114000 0.92100
REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN 15 5.76e-01 0.083300 0.92100
REACTOME DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS 19 5.76e-01 0.074000 0.92100
REACTOME PHASE II CONJUGATION OF COMPOUNDS 102 5.77e-01 -0.032000 0.92100
REACTOME PARACETAMOL ADME 26 5.77e-01 0.063200 0.92100
REACTOME METHYLATION 14 5.77e-01 0.086100 0.92100
REACTOME COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING 38 5.77e-01 0.052300 0.92100
REACTOME RAP1 SIGNALLING 16 5.78e-01 0.080300 0.92100
REACTOME EGFR TRANSACTIVATION BY GASTRIN 9 5.81e-01 0.106000 0.92500
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING 6 5.82e-01 -0.130000 0.92700
REACTOME ASPARTATE AND ASPARAGINE METABOLISM 11 5.84e-01 -0.095400 0.92800
REACTOME ION CHANNEL TRANSPORT 172 5.84e-01 0.024200 0.92800
REACTOME FORMATION OF INCISION COMPLEX IN GG NER 40 5.85e-01 0.049900 0.92800
REACTOME XENOBIOTICS 22 5.85e-01 0.067200 0.92800
REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS 15 5.87e-01 -0.081100 0.92800
REACTOME FRS MEDIATED FGFR3 SIGNALING 19 5.87e-01 -0.072000 0.92800
REACTOME TRNA AMINOACYLATION 40 5.89e-01 0.049400 0.93100
REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN 19 5.89e-01 -0.071500 0.93100
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR3 24 5.90e-01 -0.063500 0.93100
REACTOME RND1 GTPASE CYCLE 41 5.91e-01 0.048500 0.93100
REACTOME CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN 45 5.92e-01 0.046200 0.93100
REACTOME DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA 77 5.92e-01 0.035300 0.93100
REACTOME SEMAPHORIN INTERACTIONS 61 5.93e-01 0.039600 0.93100
REACTOME HS GAG DEGRADATION 19 5.93e-01 -0.070800 0.93100
REACTOME DUAL INCISION IN GG NER 39 5.94e-01 0.049400 0.93100
REACTOME RECYCLING OF EIF2 GDP 7 5.96e-01 -0.116000 0.93200
REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE 71 5.96e-01 0.036400 0.93200
REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION 10 5.96e-01 0.096700 0.93200
REACTOME SYNTHESIS OF 12 EICOSATETRAENOIC ACID DERIVATIVES 7 5.97e-01 0.115000 0.93200
REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING 16 5.97e-01 -0.076300 0.93200
REACTOME DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS 14 5.99e-01 0.081300 0.93300
REACTOME OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS 8 6.00e-01 -0.107000 0.93400
REACTOME METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES 33 6.00e-01 -0.052700 0.93400
REACTOME ACTIVATION OF RAC1 12 6.04e-01 0.086600 0.93700
REACTOME EPHRIN SIGNALING 17 6.04e-01 0.072600 0.93700
REACTOME SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS 14 6.06e-01 0.079700 0.93700
REACTOME SIGNALING BY FGFR2 IN DISEASE 42 6.06e-01 0.046000 0.93700
REACTOME DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1 9 6.07e-01 0.099200 0.93700
REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS 27 6.07e-01 0.057200 0.93700
REACTOME SPHINGOLIPID METABOLISM 84 6.09e-01 0.032300 0.93700
REACTOME CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE 49 6.09e-01 -0.042200 0.93700
REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION 45 6.10e-01 0.044000 0.93700
REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 19 6.10e-01 0.067600 0.93700
REACTOME SYNTHESIS OF KETONE BODIES 8 6.10e-01 -0.104000 0.93700
REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING 33 6.10e-01 0.051300 0.93700
REACTOME MUCOPOLYSACCHARIDOSES 10 6.11e-01 0.092800 0.93700
REACTOME DEFECTIVE CHST14 CAUSES EDS MUSCULOCONTRACTURAL TYPE 7 6.12e-01 -0.111000 0.93700
REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS 312 6.12e-01 -0.016700 0.93700
REACTOME MASTL FACILITATES MITOTIC PROGRESSION 10 6.13e-01 0.092500 0.93700
REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE 15 6.15e-01 -0.075100 0.93700
REACTOME ABACAVIR TRANSMEMBRANE TRANSPORT 5 6.15e-01 -0.130000 0.93700
REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL 41 6.15e-01 -0.045400 0.93700
REACTOME CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY 84 6.15e-01 0.031700 0.93700
REACTOME TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN 21 6.16e-01 0.063200 0.93700
REACTOME RRNA MODIFICATION IN THE MITOCHONDRION 6 6.17e-01 -0.118000 0.93700
REACTOME RIP MEDIATED NFKB ACTIVATION VIA ZBP1 16 6.17e-01 0.072300 0.93700
REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES 39 6.17e-01 0.046300 0.93700
REACTOME FGFRL1 MODULATION OF FGFR1 SIGNALING 13 6.18e-01 0.080000 0.93700
REACTOME TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE 10 6.19e-01 0.090800 0.93700
REACTOME INTERLEUKIN 21 SIGNALING 9 6.19e-01 0.095700 0.93700
REACTOME SIGNALING BY PDGF 57 6.19e-01 -0.038100 0.93700
REACTOME ESTABLISHMENT OF SISTER CHROMATID COHESION 9 6.20e-01 -0.095600 0.93700
REACTOME ATTENUATION PHASE 27 6.20e-01 0.055100 0.93700
REACTOME PROCESSING AND ACTIVATION OF SUMO 10 6.20e-01 -0.090500 0.93700
REACTOME HYALURONAN UPTAKE AND DEGRADATION 12 6.21e-01 0.082400 0.93700
REACTOME INTRINSIC PATHWAY FOR APOPTOSIS 54 6.21e-01 0.038800 0.93700
REACTOME ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA 5 6.22e-01 0.127000 0.93700
REACTOME ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS 41 6.23e-01 -0.044400 0.93800
REACTOME GAP JUNCTION DEGRADATION 12 6.23e-01 0.082000 0.93800
REACTOME N GLYCAN ANTENNAE ELONGATION 15 6.24e-01 0.073100 0.93800
REACTOME TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS 12 6.26e-01 0.081300 0.94000
REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 73 6.27e-01 -0.032900 0.94000
REACTOME VASOPRESSIN LIKE RECEPTORS 5 6.27e-01 0.126000 0.94000
REACTOME ACTIVATION OF CASPASES THROUGH APOPTOSOME MEDIATED CLEAVAGE 5 6.28e-01 -0.125000 0.94000
REACTOME GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION 14 6.29e-01 -0.074700 0.94000
REACTOME RAF INDEPENDENT MAPK1 3 ACTIVATION 22 6.29e-01 0.059500 0.94000
REACTOME IRS ACTIVATION 5 6.29e-01 0.125000 0.94000
REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP 104 6.30e-01 -0.027400 0.94000
REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL 58 6.31e-01 -0.036500 0.94100
REACTOME METABOLISM OF POLYAMINES 56 6.33e-01 -0.036900 0.94100
REACTOME GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION 7 6.33e-01 -0.104000 0.94100
REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER 18 6.33e-01 0.064900 0.94100
REACTOME PHASE 1 INACTIVATION OF FAST NA CHANNELS 6 6.34e-01 -0.112000 0.94100
REACTOME CELL CYCLE MITOTIC 539 6.35e-01 -0.012000 0.94100
REACTOME RNA POLYMERASE I TRANSCRIPTION TERMINATION 30 6.35e-01 0.050100 0.94100
REACTOME OTHER SEMAPHORIN INTERACTIONS 18 6.35e-01 0.064600 0.94100
REACTOME KERATINIZATION 210 6.36e-01 -0.019000 0.94100
REACTOME VITAMINS 6 6.36e-01 -0.111000 0.94100
REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS 19 6.37e-01 -0.062500 0.94100
REACTOME VOLTAGE GATED POTASSIUM CHANNELS 42 6.37e-01 -0.042000 0.94100
REACTOME BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA 5 6.38e-01 -0.122000 0.94100
REACTOME RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES 16 6.39e-01 -0.067700 0.94200
REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 54 6.39e-01 0.036900 0.94200
REACTOME PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR 21 6.42e-01 -0.058700 0.94400
REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING 32 6.42e-01 0.047400 0.94400
REACTOME PROSTANOID LIGAND RECEPTORS 9 6.43e-01 -0.089300 0.94400
REACTOME DRUG MEDIATED INHIBITION OF CDK4 CDK6 ACTIVITY 5 6.47e-01 -0.118000 0.94500
REACTOME LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME 11 6.47e-01 0.079800 0.94500
REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION 183 6.47e-01 0.019600 0.94500
REACTOME ENDOGENOUS STEROLS 26 6.48e-01 -0.051700 0.94500
REACTOME TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE 20 6.49e-01 0.058800 0.94500
REACTOME SIGNALING BY RNF43 MUTANTS 8 6.49e-01 0.092900 0.94500
REACTOME DERMATAN SULFATE BIOSYNTHESIS 10 6.49e-01 -0.083000 0.94500
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FYN 7 6.50e-01 -0.099000 0.94500
REACTOME PROTEIN UBIQUITINATION 76 6.51e-01 0.030000 0.94500
REACTOME RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION 6 6.51e-01 0.107000 0.94500
REACTOME MATURATION OF SARS COV 1 SPIKE PROTEIN 5 6.51e-01 0.117000 0.94500
REACTOME RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX 29 6.51e-01 -0.048500 0.94500
REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION 9 6.52e-01 -0.086900 0.94500
REACTOME SLC TRANSPORTER DISORDERS 94 6.52e-01 -0.026900 0.94500
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1 31 6.53e-01 -0.046700 0.94500
REACTOME ACTIVATION OF MATRIX METALLOPROTEINASES 30 6.53e-01 0.047400 0.94500
REACTOME REGULATION OF FZD BY UBIQUITINATION 21 6.54e-01 0.056500 0.94600
REACTOME AZATHIOPRINE ADME 22 6.56e-01 -0.054900 0.94800
REACTOME HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE 43 6.57e-01 -0.039100 0.94900
REACTOME MET RECEPTOR RECYCLING 10 6.57e-01 0.081000 0.94900
REACTOME CELLULAR SENESCENCE 189 6.59e-01 0.018600 0.94900
REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES 22 6.59e-01 0.054300 0.94900
REACTOME REPRESSION OF WNT TARGET GENES 14 6.60e-01 -0.068000 0.94900
REACTOME REGULATED PROTEOLYSIS OF P75NTR 11 6.60e-01 0.076600 0.94900
REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS 42 6.62e-01 -0.039000 0.95100
REACTOME PKMTS METHYLATE HISTONE LYSINES 64 6.63e-01 -0.031500 0.95100
REACTOME TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT 18 6.64e-01 -0.059200 0.95100
REACTOME RAS PROCESSING 22 6.64e-01 -0.053500 0.95100
REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS 11 6.66e-01 -0.075100 0.95200
REACTOME NGF STIMULATED TRANSCRIPTION 38 6.66e-01 -0.040400 0.95200
REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS 60 6.67e-01 -0.032200 0.95200
REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS 15 6.67e-01 -0.064200 0.95200
REACTOME MUSCARINIC ACETYLCHOLINE RECEPTORS 5 6.68e-01 0.111000 0.95200
REACTOME CRISTAE FORMATION 27 6.68e-01 0.047700 0.95200
REACTOME FCGR ACTIVATION 11 6.68e-01 0.074600 0.95200
REACTOME FLT3 SIGNALING IN DISEASE 28 6.69e-01 0.046700 0.95200
REACTOME DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM 38 6.70e-01 0.040000 0.95200
REACTOME PEROXISOMAL PROTEIN IMPORT 62 6.72e-01 -0.031100 0.95300
REACTOME PHASE 0 RAPID DEPOLARISATION 31 6.73e-01 -0.043800 0.95300
REACTOME UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN 6 6.73e-01 0.099400 0.95300
REACTOME RA BIOSYNTHESIS PATHWAY 22 6.73e-01 0.051900 0.95300
REACTOME TCR SIGNALING 113 6.74e-01 -0.022900 0.95300
REACTOME SURFACTANT METABOLISM 28 6.74e-01 0.045900 0.95300
REACTOME INTERACTION BETWEEN L1 AND ANKYRINS 30 6.76e-01 -0.044000 0.95600
REACTOME REGULATION OF BETA CELL DEVELOPMENT 41 6.77e-01 -0.037600 0.95600
REACTOME G1 S DNA DAMAGE CHECKPOINTS 67 6.80e-01 0.029200 0.95800
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS 11 6.80e-01 -0.071800 0.95800
REACTOME SUMO IS PROTEOLYTICALLY PROCESSED 6 6.80e-01 -0.097200 0.95800
REACTOME RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION 6 6.81e-01 0.096900 0.95800
REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK 28 6.82e-01 0.044700 0.95800
REACTOME VISUAL PHOTOTRANSDUCTION 93 6.82e-01 0.024500 0.95800
REACTOME INTERLEUKIN 10 SIGNALING 43 6.83e-01 -0.036000 0.95800
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX 19 6.85e-01 0.053800 0.95800
REACTOME DEGRADATION OF CYSTEINE AND HOMOCYSTEINE 15 6.85e-01 0.060500 0.95800
REACTOME METABOLISM OF FAT SOLUBLE VITAMINS 46 6.85e-01 -0.034500 0.95800
REACTOME DNA DAMAGE RECOGNITION IN GG NER 36 6.86e-01 -0.039000 0.95800
REACTOME MOLYBDENUM COFACTOR BIOSYNTHESIS 6 6.87e-01 -0.095000 0.95800
REACTOME EPH EPHRIN SIGNALING 90 6.88e-01 0.024500 0.95800
REACTOME HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS 9 6.88e-01 -0.077300 0.95800
REACTOME MRNA SPLICING MINOR PATHWAY 49 6.88e-01 -0.033200 0.95800
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION 27 6.88e-01 -0.044600 0.95800
REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR 79 6.88e-01 0.026100 0.95800
REACTOME N GLYCAN TRIMMING AND ELONGATION IN THE CIS GOLGI 5 6.90e-01 0.103000 0.95900
REACTOME SARS COV 1 INFECTION 136 6.91e-01 -0.019700 0.96000
REACTOME SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE 91 6.92e-01 0.024000 0.96000
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX IN CANCER 8 6.94e-01 0.080400 0.96200
REACTOME INITIATION OF NUCLEAR ENVELOPE NE REFORMATION 18 6.95e-01 0.053500 0.96200
REACTOME HISTIDINE CATABOLISM 8 6.95e-01 0.080000 0.96200
REACTOME ATTACHMENT AND ENTRY 16 6.96e-01 0.056400 0.96200
REACTOME SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION 8 6.97e-01 0.079400 0.96200
REACTOME INTERLEUKIN 37 SIGNALING 20 6.99e-01 -0.050000 0.96200
REACTOME TRANSLESION SYNTHESIS BY POLH 19 6.99e-01 -0.051300 0.96200
REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS 63 7.00e-01 -0.028100 0.96200
REACTOME INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES 28 7.01e-01 0.042000 0.96200
REACTOME CELLULAR RESPONSE TO HYPOXIA 74 7.02e-01 -0.025700 0.96200
REACTOME SIGNALING BY EGFR 49 7.02e-01 0.031600 0.96200
REACTOME CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT 19 7.03e-01 -0.050600 0.96200
REACTOME TYSND1 CLEAVES PEROXISOMAL PROTEINS 7 7.05e-01 0.082600 0.96200
REACTOME ESTROGEN DEPENDENT GENE EXPRESSION 140 7.06e-01 0.018500 0.96200
REACTOME BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA 17 7.06e-01 0.052800 0.96200
REACTOME LDL REMODELING 6 7.07e-01 0.088600 0.96200
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS 14 7.07e-01 0.058000 0.96200
REACTOME SARS COV INFECTIONS 392 7.07e-01 -0.011100 0.96200
REACTOME HDR THROUGH HOMOLOGOUS RECOMBINATION HRR 66 7.07e-01 -0.026700 0.96200
REACTOME RHOBTB3 ATPASE CYCLE 8 7.08e-01 0.076500 0.96200
REACTOME PHASE 2 PLATEAU PHASE 14 7.09e-01 0.057700 0.96200
REACTOME RHOH GTPASE CYCLE 37 7.09e-01 -0.035400 0.96200
REACTOME UCH PROTEINASES 99 7.10e-01 -0.021700 0.96200
REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE 37 7.10e-01 -0.035400 0.96200
REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS 21 7.11e-01 -0.046800 0.96200
REACTOME VLDL ASSEMBLY 5 7.11e-01 -0.095600 0.96200
REACTOME CD28 DEPENDENT VAV1 PATHWAY 11 7.12e-01 -0.064400 0.96200
REACTOME POLB DEPENDENT LONG PATCH BASE EXCISION REPAIR 8 7.12e-01 -0.075400 0.96200
REACTOME GLUCAGON TYPE LIGAND RECEPTORS 32 7.14e-01 0.037500 0.96200
REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS 20 7.14e-01 0.047300 0.96200
REACTOME ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS 27 7.14e-01 0.040700 0.96200
REACTOME IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN 5 7.15e-01 -0.094500 0.96200
REACTOME OXIDATIVE STRESS INDUCED SENESCENCE 118 7.15e-01 -0.019500 0.96200
REACTOME GLUCONEOGENESIS 33 7.15e-01 0.036800 0.96200
REACTOME SIGNALING BY WNT IN CANCER 32 7.16e-01 0.037200 0.96200
REACTOME EGFR INTERACTS WITH PHOSPHOLIPASE C GAMMA 9 7.18e-01 0.069500 0.96200
REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS 16 7.18e-01 0.052100 0.96200
REACTOME CHYLOMICRON ASSEMBLY 10 7.19e-01 -0.065700 0.96200
REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI 26 7.20e-01 0.040600 0.96200
REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER 49 7.20e-01 0.029500 0.96200
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING 5 7.21e-01 0.092300 0.96200
REACTOME MIRO GTPASE CYCLE 8 7.21e-01 0.073000 0.96200
REACTOME CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION 11 7.21e-01 0.062100 0.96200
REACTOME REGULATION OF PTEN LOCALIZATION 8 7.22e-01 0.072700 0.96200
REACTOME INTESTINAL ABSORPTION 5 7.22e-01 0.091800 0.96200
REACTOME SUMO IS TRANSFERRED FROM E1 TO E2 UBE2I UBC9 7 7.22e-01 -0.077600 0.96200
REACTOME JOSEPHIN DOMAIN DUBS 11 7.23e-01 0.061800 0.96200
REACTOME NONCANONICAL ACTIVATION OF NOTCH3 8 7.23e-01 -0.072300 0.96200
REACTOME CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND 16 7.24e-01 -0.051000 0.96200
REACTOME REGULATED NECROSIS 57 7.25e-01 -0.027000 0.96200
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2 13 7.25e-01 0.056300 0.96200
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS 121 7.26e-01 -0.018500 0.96200
REACTOME EPHA MEDIATED GROWTH CONE COLLAPSE 29 7.26e-01 0.037600 0.96200
REACTOME BASIGIN INTERACTIONS 24 7.27e-01 0.041200 0.96200
REACTOME APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS 87 7.27e-01 -0.021700 0.96200
REACTOME DEADENYLATION DEPENDENT MRNA DECAY 56 7.28e-01 0.026900 0.96200
REACTOME SHC1 EVENTS IN ERBB2 SIGNALING 22 7.28e-01 -0.042800 0.96200
REACTOME DEFENSINS 33 7.29e-01 -0.034800 0.96200
REACTOME TNFR2 NON CANONICAL NF KB PATHWAY 96 7.30e-01 0.020400 0.96200
REACTOME ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS 17 7.30e-01 0.048400 0.96200
REACTOME INTERLEUKIN 6 FAMILY SIGNALING 24 7.31e-01 0.040500 0.96200
REACTOME TRAFFICKING OF AMPA RECEPTORS 29 7.31e-01 -0.036900 0.96200
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH CDK5 6 7.32e-01 -0.080800 0.96200
REACTOME PI3K EVENTS IN ERBB2 SIGNALING 16 7.32e-01 -0.049400 0.96200
REACTOME NUCLEOTIDE CATABOLISM 35 7.33e-01 0.033400 0.96200
REACTOME NETRIN 1 SIGNALING 49 7.33e-01 -0.028200 0.96200
REACTOME SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS 74 7.33e-01 -0.022900 0.96200
REACTOME SYNTHESIS OF PIPS AT THE ER MEMBRANE 5 7.33e-01 -0.088000 0.96200
REACTOME PLATELET SENSITIZATION BY LDL 17 7.36e-01 -0.047200 0.96200
REACTOME AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA 54 7.37e-01 -0.026400 0.96200
REACTOME METABOLISM OF AMINE DERIVED HORMONES 17 7.37e-01 0.047000 0.96200
REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE 10 7.38e-01 0.061100 0.96200
REACTOME SIGNALING BY PTK6 54 7.38e-01 0.026300 0.96200
REACTOME DEFECTIVE CSF2RB CAUSES SMDP5 7 7.38e-01 -0.073000 0.96200
REACTOME METABOLISM OF COFACTORS 19 7.39e-01 -0.044200 0.96200
REACTOME MET PROMOTES CELL MOTILITY 41 7.39e-01 -0.030100 0.96200
REACTOME AGGREPHAGY 42 7.41e-01 0.029400 0.96200
REACTOME HIV INFECTION 223 7.42e-01 -0.012800 0.96200
REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION 145 7.42e-01 0.015800 0.96200
REACTOME PYROPTOSIS 27 7.42e-01 0.036600 0.96200
REACTOME RESPONSE OF MTB TO PHAGOCYTOSIS 22 7.42e-01 0.040500 0.96200
REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS 11 7.42e-01 -0.057300 0.96200
REACTOME HDR THROUGH SINGLE STRAND ANNEALING SSA 37 7.44e-01 -0.031100 0.96200
REACTOME REGULATION OF SIGNALING BY CBL 22 7.44e-01 0.040300 0.96200
REACTOME FGFR1 LIGAND BINDING AND ACTIVATION 15 7.45e-01 0.048600 0.96200
REACTOME SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA 52 7.45e-01 -0.026000 0.96200
REACTOME CTLA4 INHIBITORY SIGNALING 21 7.46e-01 0.040900 0.96200
REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING 28 7.46e-01 0.035400 0.96200
REACTOME PROCESSING OF SMDT1 16 7.47e-01 0.046600 0.96200
REACTOME SYNTHESIS OF GDP MANNOSE 5 7.47e-01 -0.083200 0.96200
REACTOME GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER 25 7.48e-01 -0.037200 0.96200
REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE 20 7.48e-01 -0.041500 0.96200
REACTOME DIGESTION OF DIETARY LIPID 7 7.49e-01 0.069900 0.96200
REACTOME LATE ENDOSOMAL MICROAUTOPHAGY 33 7.49e-01 0.032200 0.96200
REACTOME SUPPRESSION OF PHAGOSOMAL MATURATION 13 7.49e-01 0.051300 0.96200
REACTOME MITOPHAGY 28 7.49e-01 0.034900 0.96200
REACTOME CHOLINE CATABOLISM 6 7.51e-01 -0.074800 0.96300
REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX 21 7.51e-01 0.039900 0.96300
REACTOME DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A 5 7.52e-01 -0.081700 0.96300
REACTOME INTERLEUKIN 2 SIGNALING 11 7.53e-01 -0.054900 0.96300
REACTOME EGFR DOWNREGULATION 30 7.53e-01 0.033200 0.96300
REACTOME THE ACTIVATION OF ARYLSULFATASES 8 7.55e-01 0.063700 0.96300
REACTOME MAPK3 ERK1 ACTIVATION 10 7.56e-01 0.056800 0.96300
REACTOME INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL 14 7.57e-01 0.047800 0.96300
REACTOME SPRY REGULATION OF FGF SIGNALING 16 7.57e-01 0.044700 0.96300
REACTOME DISEASES OF MITOTIC CELL CYCLE 37 7.58e-01 0.029300 0.96300
REACTOME DSCAM INTERACTIONS 11 7.58e-01 0.053600 0.96300
REACTOME PYRIMIDINE CATABOLISM 12 7.59e-01 -0.051200 0.96300
REACTOME DEFECTIVE EXT2 CAUSES EXOSTOSES 2 12 7.59e-01 0.051100 0.96300
REACTOME PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING 5 7.60e-01 -0.078900 0.96300
REACTOME PLATELET AGGREGATION PLUG FORMATION 39 7.60e-01 0.028200 0.96300
REACTOME SIGNALING BY FGFR4 IN DISEASE 11 7.61e-01 0.053000 0.96300
REACTOME FRS MEDIATED FGFR1 SIGNALING 23 7.61e-01 -0.036600 0.96300
REACTOME HIV ELONGATION ARREST AND RECOVERY 33 7.62e-01 0.030400 0.96300
REACTOME CHOLESTEROL BIOSYNTHESIS 25 7.64e-01 0.034700 0.96300
REACTOME IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS 17 7.64e-01 0.042100 0.96300
REACTOME RMTS METHYLATE HISTONE ARGININES 72 7.64e-01 -0.020500 0.96300
REACTOME INTERLEUKIN 2 FAMILY SIGNALING 40 7.65e-01 -0.027300 0.96300
REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY 10 7.65e-01 0.054500 0.96300
REACTOME TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS 82 7.65e-01 0.019100 0.96300
REACTOME SIGNALING BY FGFR2 72 7.66e-01 0.020300 0.96300
REACTOME TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY 30 7.66e-01 -0.031400 0.96300
REACTOME RESOLUTION OF ABASIC SITES AP SITES 38 7.67e-01 -0.027800 0.96400
REACTOME NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 11 7.69e-01 0.051200 0.96400
REACTOME MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS 17 7.70e-01 0.041000 0.96400
REACTOME VITAMIN D CALCIFEROL METABOLISM 12 7.70e-01 0.048700 0.96400
REACTOME SIGNALING BY FGFR1 49 7.71e-01 -0.024100 0.96400
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2 17 7.71e-01 0.040800 0.96400
REACTOME OAS ANTIVIRAL RESPONSE 8 7.71e-01 -0.059400 0.96400
REACTOME CYTOSOLIC TRNA AMINOACYLATION 22 7.72e-01 -0.035700 0.96400
REACTOME SELECTIVE AUTOPHAGY 79 7.73e-01 -0.018800 0.96400
REACTOME SMOOTH MUSCLE CONTRACTION 43 7.73e-01 -0.025400 0.96400
REACTOME DNA DOUBLE STRAND BREAK REPAIR 162 7.74e-01 -0.013100 0.96400
REACTOME GASTRULATION 49 7.76e-01 0.023500 0.96400
REACTOME SEMA4D IN SEMAPHORIN SIGNALING 24 7.76e-01 -0.033600 0.96400
REACTOME INACTIVATION OF CDC42 AND RAC1 8 7.77e-01 -0.058000 0.96400
REACTOME PROTEIN METHYLATION 17 7.77e-01 -0.039700 0.96400
REACTOME MAP2K AND MAPK ACTIVATION 38 7.77e-01 0.026500 0.96400
REACTOME PI 3K CASCADE FGFR2 22 7.78e-01 0.034800 0.96400
REACTOME PROLONGED ERK ACTIVATION EVENTS 14 7.78e-01 -0.043500 0.96400
REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER 81 7.79e-01 -0.018000 0.96400
REACTOME ER TO GOLGI ANTEROGRADE TRANSPORT 152 7.79e-01 0.013200 0.96400
REACTOME LAMININ INTERACTIONS 28 7.79e-01 -0.030600 0.96400
REACTOME INTERLEUKIN 23 SIGNALING 9 7.81e-01 0.053400 0.96400
REACTOME DISINHIBITION OF SNARE FORMATION 5 7.82e-01 0.071400 0.96400
REACTOME CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY 25 7.84e-01 -0.031700 0.96400
REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS 17 7.85e-01 -0.038300 0.96400
REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING 30 7.85e-01 0.028800 0.96400
REACTOME SIGNALING BY FGFR3 39 7.85e-01 -0.025200 0.96400
REACTOME FGFR2 LIGAND BINDING AND ACTIVATION 19 7.86e-01 0.036100 0.96400
REACTOME UB SPECIFIC PROCESSING PROTEASES 187 7.86e-01 0.011500 0.96400
REACTOME SUMO IS CONJUGATED TO E1 UBA2 SAE1 5 7.86e-01 -0.070000 0.96400
REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES 12 7.87e-01 0.045100 0.96400
REACTOME PHOSPHORYLATION OF EMI1 6 7.87e-01 0.063600 0.96400
REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING 34 7.89e-01 0.026500 0.96400
REACTOME LYSOSPHINGOLIPID AND LPA RECEPTORS 14 7.89e-01 0.041200 0.96400
REACTOME INFECTION WITH MYCOBACTERIUM TUBERCULOSIS 25 7.91e-01 -0.030600 0.96400
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR2 29 7.91e-01 -0.028400 0.96400
REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4 33 7.92e-01 -0.026500 0.96400
REACTOME TNF SIGNALING 54 7.92e-01 0.020700 0.96400
REACTOME TIE2 SIGNALING 18 7.92e-01 0.035800 0.96400
REACTOME RUNX3 REGULATES CDKN1A TRANSCRIPTION 7 7.93e-01 0.057300 0.96400
REACTOME SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA PHE 6 7.94e-01 0.061600 0.96400
REACTOME VLDL CLEARANCE 6 7.95e-01 -0.061200 0.96400
REACTOME DNA STRAND ELONGATION 31 7.96e-01 -0.026900 0.96400
REACTOME STIMULI SENSING CHANNELS 100 7.96e-01 0.015000 0.96400
REACTOME FORMATION OF APOPTOSOME 10 7.96e-01 -0.047100 0.96400
REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION 20 7.99e-01 -0.033000 0.96400
REACTOME INTERLEUKIN 35 SIGNALLING 12 8.00e-01 0.042300 0.96400
REACTOME RESPIRATORY ELECTRON TRANSPORT 90 8.00e-01 -0.015500 0.96400
REACTOME HIV TRANSCRIPTION INITIATION 43 8.00e-01 0.022300 0.96400
REACTOME DEFECTS IN VITAMIN AND COFACTOR METABOLISM 21 8.00e-01 0.031900 0.96400
REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A 26 8.01e-01 -0.028500 0.96400
REACTOME ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS 87 8.01e-01 0.015600 0.96400
REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX 39 8.01e-01 -0.023300 0.96400
REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT 159 8.01e-01 0.011600 0.96400
REACTOME SUMOYLATION OF TRANSCRIPTION FACTORS 20 8.03e-01 0.032200 0.96400
REACTOME TRAIL SIGNALING 8 8.03e-01 -0.050900 0.96400
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH PI3K 7 8.03e-01 -0.054300 0.96400
REACTOME INTERLEUKIN 36 PATHWAY 7 8.04e-01 -0.054200 0.96400
REACTOME SPERM MOTILITY AND TAXES 9 8.04e-01 -0.047800 0.96400
REACTOME DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS 25 8.04e-01 0.028600 0.96400
REACTOME ACTIVATION OF AMPK DOWNSTREAM OF NMDARS 28 8.05e-01 -0.026900 0.96400
REACTOME SIGNALLING TO ERKS 34 8.06e-01 0.024400 0.96400
REACTOME ORC1 REMOVAL FROM CHROMATIN 70 8.06e-01 0.017000 0.96400
REACTOME EPHB MEDIATED FORWARD SIGNALING 41 8.06e-01 0.022100 0.96400
REACTOME APOPTOTIC FACTOR MEDIATED RESPONSE 19 8.07e-01 -0.032400 0.96400
REACTOME RETINOID CYCLE DISEASE EVENTS 11 8.08e-01 0.042300 0.96400
REACTOME ALK MUTANTS BIND TKIS 12 8.09e-01 0.040400 0.96400
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES 10 8.09e-01 -0.044200 0.96400
REACTOME ATTACHMENT OF GPI ANCHOR TO UPAR 7 8.09e-01 -0.052800 0.96400
REACTOME RUNX3 REGULATES P14 ARF 10 8.09e-01 -0.044100 0.96400
REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE 63 8.10e-01 -0.017500 0.96400
REACTOME MAPK1 ERK2 ACTIVATION 9 8.10e-01 0.046300 0.96400
REACTOME DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE 30 8.11e-01 0.025200 0.96400
REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES 46 8.13e-01 -0.020200 0.96400
REACTOME FRS MEDIATED FGFR2 SIGNALING 24 8.13e-01 -0.027900 0.96400
REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS 15 8.14e-01 -0.035200 0.96400
REACTOME ACTIVATION OF C3 AND C5 6 8.14e-01 -0.055500 0.96400
REACTOME INTERFERON GAMMA SIGNALING 88 8.14e-01 0.014500 0.96400
REACTOME ACYL CHAIN REMODELING OF CL 5 8.15e-01 0.060600 0.96400
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES 15 8.15e-01 0.035000 0.96400
REACTOME MET ACTIVATES RAS SIGNALING 11 8.15e-01 0.040700 0.96400
REACTOME ELASTIC FIBRE FORMATION 44 8.16e-01 0.020300 0.96400
REACTOME ORGANIC ANION TRANSPORTERS 10 8.17e-01 0.042300 0.96400
REACTOME VXPX CARGO TARGETING TO CILIUM 20 8.17e-01 0.029900 0.96400
REACTOME GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION 34 8.17e-01 0.022900 0.96400
REACTOME DEVELOPMENTAL BIOLOGY 1115 8.17e-01 -0.004100 0.96400
REACTOME ERBB2 ACTIVATES PTK6 SIGNALING 13 8.18e-01 -0.036800 0.96400
REACTOME SIGNALING BY CSF3 G CSF 30 8.19e-01 -0.024200 0.96400
REACTOME TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA 17 8.19e-01 0.032000 0.96400
REACTOME RUNX2 REGULATES BONE DEVELOPMENT 29 8.19e-01 0.024500 0.96400
REACTOME FGFR3 LIGAND BINDING AND ACTIVATION 12 8.20e-01 -0.038000 0.96400
REACTOME REGULATION OF TP53 ACTIVITY THROUGH METHYLATION 19 8.20e-01 -0.030100 0.96400
REACTOME RHO GTPASES ACTIVATE KTN1 11 8.22e-01 0.039200 0.96500
REACTOME PI 3K CASCADE FGFR1 21 8.23e-01 0.028100 0.96600
REACTOME BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA 5 8.23e-01 -0.057600 0.96600
REACTOME TRIGLYCERIDE BIOSYNTHESIS 12 8.26e-01 0.036500 0.96900
REACTOME TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER 76 8.28e-01 -0.014400 0.96900
REACTOME TRANSCRIPTION OF THE HIV GENOME 66 8.28e-01 0.015500 0.96900
REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM 20 8.29e-01 0.027900 0.96900
REACTOME HATS ACETYLATE HISTONES 129 8.30e-01 -0.010900 0.96900
REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION 59 8.30e-01 0.016100 0.96900
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING 11 8.30e-01 0.037300 0.96900
REACTOME RNA POLYMERASE II TRANSCRIBES SNRNA GENES 77 8.31e-01 0.014000 0.97000
REACTOME CONSTITUTIVE SIGNALING BY EGFRVIII 15 8.33e-01 0.031400 0.97100
REACTOME CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS 100 8.34e-01 -0.012100 0.97100
REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS 11 8.35e-01 -0.036200 0.97200
REACTOME STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS 10 8.38e-01 -0.037300 0.97400
REACTOME FGFR3B LIGAND BINDING AND ACTIVATION 7 8.39e-01 -0.044400 0.97400
REACTOME CROSS PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS PHAGOSOMES 6 8.39e-01 -0.047800 0.97400
REACTOME ACYL CHAIN REMODELLING OF PC 27 8.40e-01 -0.022500 0.97400
REACTOME ACYL CHAIN REMODELLING OF PS 22 8.40e-01 -0.024900 0.97400
REACTOME EICOSANOID LIGAND BINDING RECEPTORS 14 8.42e-01 -0.030800 0.97500
REACTOME COPI MEDIATED ANTEROGRADE TRANSPORT 101 8.42e-01 -0.011400 0.97500
REACTOME NADE MODULATES DEATH SIGNALLING 5 8.43e-01 0.051200 0.97500
REACTOME INSULIN PROCESSING 24 8.43e-01 -0.023300 0.97500
REACTOME FCERI MEDIATED MAPK ACTIVATION 32 8.45e-01 0.019900 0.97500
REACTOME DNA REPAIR 321 8.47e-01 -0.006280 0.97500
REACTOME SERINE BIOSYNTHESIS 9 8.47e-01 0.037100 0.97500
REACTOME FORMATION OF TC NER PRE INCISION COMPLEX 51 8.47e-01 -0.015600 0.97500
REACTOME NEF MEDIATED CD4 DOWN REGULATION 9 8.47e-01 0.037100 0.97500
REACTOME TNFR1 INDUCED PROAPOPTOTIC SIGNALING 23 8.47e-01 -0.023200 0.97500
REACTOME G2 M DNA REPLICATION CHECKPOINT 5 8.49e-01 -0.049200 0.97500
REACTOME DEFECTS IN COBALAMIN B12 METABOLISM 13 8.49e-01 -0.030500 0.97500
REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS 118 8.50e-01 -0.010100 0.97500
REACTOME ION TRANSPORT BY P TYPE ATPASES 51 8.51e-01 -0.015200 0.97500
REACTOME GPVI MEDIATED ACTIVATION CASCADE 35 8.51e-01 -0.018300 0.97500
REACTOME TELOMERE EXTENSION BY TELOMERASE 22 8.53e-01 0.022900 0.97500
REACTOME RUNX2 REGULATES CHONDROCYTE MATURATION 5 8.53e-01 -0.047900 0.97500
REACTOME PURINE CATABOLISM 17 8.53e-01 0.026000 0.97500
REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS 39 8.53e-01 0.017100 0.97500
REACTOME KINESINS 59 8.54e-01 -0.013800 0.97500
REACTOME DISEASES OF METABOLISM 237 8.54e-01 0.006920 0.97500
REACTOME ROLE OF ABL IN ROBO SLIT SIGNALING 8 8.55e-01 0.037400 0.97500
REACTOME SHC1 EVENTS IN EGFR SIGNALING 14 8.55e-01 0.028300 0.97500
REACTOME SHC RELATED EVENTS TRIGGERED BY IGF1R 9 8.56e-01 -0.034900 0.97500
REACTOME TLR3 MEDIATED TICAM1 DEPENDENT PROGRAMMED CELL DEATH 6 8.56e-01 0.042700 0.97500
REACTOME TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY 16 8.58e-01 0.025900 0.97500
REACTOME ACTIVATION OF SMO 18 8.58e-01 -0.024300 0.97500
REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION 10 8.59e-01 0.032500 0.97500
REACTOME HSF1 ACTIVATION 29 8.59e-01 0.019100 0.97500
REACTOME DEFECTIVE GALNT3 CAUSES HFTC 16 8.59e-01 -0.025600 0.97500
REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION 90 8.60e-01 0.010800 0.97500
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX 91 8.60e-01 -0.010700 0.97500
REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS 37 8.61e-01 0.016600 0.97500
REACTOME SODIUM PROTON EXCHANGERS 7 8.61e-01 0.038200 0.97500
REACTOME CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS 19 8.64e-01 0.022700 0.97700
REACTOME PRE NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM 6 8.65e-01 0.040200 0.97700
REACTOME THYROXINE BIOSYNTHESIS 10 8.65e-01 0.031100 0.97700
REACTOME SIGNALLING TO RAS 20 8.66e-01 0.021800 0.97700
REACTOME NEPHRIN FAMILY INTERACTIONS 22 8.68e-01 0.020400 0.97700
REACTOME ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS 20 8.69e-01 0.021400 0.97700
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY DVL INTERACTING PROTEINS 5 8.69e-01 0.042500 0.97700
REACTOME TERMINATION OF TRANSLESION DNA SYNTHESIS 32 8.69e-01 -0.016800 0.97700
REACTOME PHOSPHORYLATION OF THE APC C 20 8.69e-01 -0.021200 0.97700
REACTOME REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS 11 8.70e-01 0.028500 0.97700
REACTOME DUAL INCISION IN TC NER 63 8.70e-01 0.011900 0.97700
REACTOME ACYL CHAIN REMODELLING OF PG 18 8.71e-01 -0.022100 0.97700
REACTOME PLASMA LIPOPROTEIN ASSEMBLY 19 8.72e-01 0.021400 0.97700
REACTOME REGULATION OF IFNG SIGNALING 14 8.72e-01 -0.024900 0.97700
REACTOME GLUCOSE METABOLISM 90 8.72e-01 -0.009820 0.97700
REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY 14 8.72e-01 0.024800 0.97700
REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION 15 8.75e-01 0.023400 0.98000
REACTOME ANTIGEN PROCESSING CROSS PRESENTATION 98 8.77e-01 -0.009060 0.98100
REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY 29 8.78e-01 -0.016500 0.98100
REACTOME NEF AND SIGNAL TRANSDUCTION 8 8.78e-01 0.031200 0.98100
REACTOME S PHASE 159 8.79e-01 0.007000 0.98100
REACTOME THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT 77 8.79e-01 0.010000 0.98100
REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX 8 8.82e-01 -0.030200 0.98300
REACTOME SHC MEDIATED CASCADE FGFR4 19 8.85e-01 -0.019200 0.98600
REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ 6 8.85e-01 0.034000 0.98600
REACTOME COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM 21 8.86e-01 -0.018000 0.98600
REACTOME DISEASES OF DNA REPAIR 51 8.89e-01 -0.011200 0.98700
REACTOME TRANSPORT AND SYNTHESIS OF PAPS 6 8.90e-01 0.032600 0.98700
REACTOME NEUROTRANSMITTER CLEARANCE 9 8.90e-01 -0.026600 0.98700
REACTOME LOSS OF FUNCTION OF SMAD2 3 IN CANCER 7 8.91e-01 0.030000 0.98700
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1 16 8.91e-01 -0.019800 0.98700
REACTOME SIGNALING BY LEPTIN 11 8.91e-01 0.023900 0.98700
REACTOME INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION 21 8.91e-01 -0.017200 0.98700
REACTOME DEFECTIVE RIPK1 MEDIATED REGULATED NECROSIS 7 8.94e-01 0.029000 0.98800
REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES 38 8.96e-01 0.012200 0.98800
REACTOME DOWNREGULATION OF ERBB4 SIGNALING 9 8.97e-01 0.024800 0.98800
REACTOME ANDROGEN BIOSYNTHESIS 11 8.97e-01 -0.022400 0.98800
REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION 19 8.98e-01 0.017000 0.98800
REACTOME DISEASES OF GLYCOSYLATION 137 8.99e-01 -0.006270 0.98800
REACTOME TP53 REGULATES METABOLIC GENES 81 9.01e-01 -0.007990 0.98800
REACTOME RHO GTPASE EFFECTORS 305 9.01e-01 0.004130 0.98800
REACTOME SIGNALING BY FGFR4 40 9.01e-01 -0.011300 0.98800
REACTOME ADHERENS JUNCTIONS INTERACTIONS 33 9.02e-01 0.012400 0.98800
REACTOME RHO GTPASES ACTIVATE FORMINS 136 9.02e-01 0.006130 0.98800
REACTOME BH3 ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI APOPTOTIC BCL 2 MEMBERS 9 9.02e-01 0.023700 0.98800
REACTOME RETROGRADE NEUROTROPHIN SIGNALLING 14 9.02e-01 0.019000 0.98800
REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION 36 9.02e-01 0.011800 0.98800
REACTOME MISCELLANEOUS SUBSTRATES 12 9.03e-01 -0.020400 0.98800
REACTOME REACTIONS SPECIFIC TO THE COMPLEX N GLYCAN SYNTHESIS PATHWAY 10 9.03e-01 0.022100 0.98800
REACTOME RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK 47 9.04e-01 -0.010100 0.98800
REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B 24 9.05e-01 0.014100 0.98800
REACTOME RESOLUTION OF D LOOP STRUCTURES 33 9.06e-01 0.011900 0.98800
REACTOME PP2A MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS 6 9.07e-01 -0.027600 0.98800
REACTOME INFECTIOUS DISEASE 910 9.07e-01 0.002280 0.98800
REACTOME RECYCLING OF BILE ACIDS AND SALTS 18 9.07e-01 0.015800 0.98800
REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS 86 9.08e-01 0.007180 0.98800
REACTOME STABILIZATION OF P53 56 9.09e-01 -0.008850 0.98800
REACTOME REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA 15 9.09e-01 0.017000 0.98800
REACTOME TRP CHANNELS 27 9.10e-01 0.012500 0.98800
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES 11 9.11e-01 -0.019500 0.98800
REACTOME CRMPS IN SEMA3A SIGNALING 15 9.11e-01 -0.016700 0.98800
REACTOME SIGNALING BY FGFR 85 9.11e-01 -0.006990 0.98800
REACTOME SIGNAL ATTENUATION 10 9.12e-01 -0.020200 0.98800
REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES 14 9.13e-01 -0.016900 0.98800
REACTOME HEDGEHOG ON STATE 85 9.13e-01 0.006870 0.98800
REACTOME SHC MEDIATED CASCADE FGFR1 21 9.13e-01 0.013800 0.98800
REACTOME TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS 36 9.14e-01 0.010400 0.98800
REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS 46 9.14e-01 0.009230 0.98800
REACTOME BIOLOGICAL OXIDATIONS 210 9.15e-01 0.004290 0.98900
REACTOME MUSCLE CONTRACTION 197 9.15e-01 -0.004400 0.98900
REACTOME FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES 29 9.17e-01 0.011200 0.98900
REACTOME ACTIVATION OF NIMA KINASES NEK9 NEK6 NEK7 7 9.17e-01 -0.022600 0.98900
REACTOME GOLGI TO ER RETROGRADE TRANSPORT 132 9.17e-01 0.005220 0.98900
REACTOME DNA DAMAGE BYPASS 47 9.18e-01 0.008730 0.98900
REACTOME COMPLEX I BIOGENESIS 49 9.18e-01 0.008490 0.98900
REACTOME TRANSLESION SYNTHESIS BY POLK 17 9.20e-01 -0.014000 0.98900
REACTOME PIWI INTERACTING RNA PIRNA BIOGENESIS 29 9.21e-01 0.010700 0.98900
REACTOME SHC MEDIATED CASCADE FGFR3 17 9.21e-01 -0.013900 0.98900
REACTOME FERTILIZATION 26 9.21e-01 -0.011200 0.99000
REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE 20 9.23e-01 0.012500 0.99000
REACTOME INFLAMMASOMES 21 9.25e-01 0.011800 0.99000
REACTOME FGFR2C LIGAND BINDING AND ACTIVATION 12 9.26e-01 0.015500 0.99000
REACTOME NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY 6 9.28e-01 -0.021400 0.99000
REACTOME CARDIAC CONDUCTION 125 9.28e-01 -0.004670 0.99000
REACTOME SIGNALING BY MET 78 9.28e-01 0.005890 0.99000
REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS 23 9.28e-01 0.010800 0.99000
REACTOME NUCLEAR ENVELOPE NE REASSEMBLY 74 9.30e-01 -0.005900 0.99000
REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY 15 9.32e-01 0.012700 0.99000
REACTOME SARS COV 1 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS 16 9.32e-01 -0.012300 0.99000
REACTOME DISEASES ASSOCIATED WITH SURFACTANT METABOLISM 9 9.32e-01 -0.016400 0.99000
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION 138 9.32e-01 0.004200 0.99000
REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS 12 9.33e-01 0.014000 0.99000
REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL 129 9.34e-01 0.004250 0.99000
REACTOME REGULATION OF RUNX3 EXPRESSION AND ACTIVITY 54 9.34e-01 0.006560 0.99000
REACTOME ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS 20 9.34e-01 0.010700 0.99000
REACTOME SYNTHESIS OF DNA 119 9.34e-01 0.004400 0.99000
REACTOME FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS 8 9.35e-01 0.016700 0.99000
REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION 23 9.35e-01 -0.009830 0.99000
REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING 26 9.35e-01 0.009210 0.99000
REACTOME PI3K AKT ACTIVATION 9 9.36e-01 -0.015500 0.99000
REACTOME ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS 5 9.36e-01 -0.020700 0.99000
REACTOME TRANSPORT OF ORGANIC ANIONS 10 9.37e-01 -0.014400 0.99000
REACTOME SARS COV 2 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS 12 9.37e-01 0.013100 0.99000
REACTOME PHYSIOLOGICAL FACTORS 14 9.38e-01 -0.012100 0.99000
REACTOME RHO GTPASES ACTIVATE PAKS 19 9.38e-01 0.010400 0.99000
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES 255 9.39e-01 -0.002780 0.99000
REACTOME HYDROLYSIS OF LPC 9 9.39e-01 -0.014700 0.99000
REACTOME SMALL INTERFERING RNA SIRNA BIOGENESIS 9 9.39e-01 -0.014700 0.99000
REACTOME SIGNALING BY NTRKS 132 9.41e-01 -0.003730 0.99000
REACTOME GLYCOLYSIS 70 9.41e-01 -0.005100 0.99000
REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING 12 9.42e-01 0.012200 0.99000
REACTOME LTC4 CYSLTR MEDIATED IL4 PRODUCTION 6 9.42e-01 0.017100 0.99000
REACTOME INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING 103 9.43e-01 -0.004110 0.99000
REACTOME SIGNALING BY LRP5 MUTANTS 6 9.44e-01 -0.016700 0.99000
REACTOME RIBAVIRIN ADME 11 9.44e-01 -0.012200 0.99000
REACTOME ACYL CHAIN REMODELLING OF PE 29 9.46e-01 0.007320 0.99000
REACTOME AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY 8 9.46e-01 0.013800 0.99000
REACTOME MATURATION OF SARS COV 2 NUCLEOPROTEIN 15 9.47e-01 0.009940 0.99000
REACTOME GLYCOSPHINGOLIPID METABOLISM 39 9.47e-01 0.006160 0.99000
REACTOME WAX AND PLASMALOGEN BIOSYNTHESIS 5 9.47e-01 0.017100 0.99000
REACTOME KETONE BODY METABOLISM 9 9.48e-01 -0.012600 0.99000
REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE 11 9.49e-01 -0.011200 0.99000
REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 11 9.49e-01 0.011200 0.99000
REACTOME GLYCOGEN STORAGE DISEASES 15 9.50e-01 0.009290 0.99000
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR4 14 9.50e-01 -0.009590 0.99000
REACTOME DAP12 INTERACTIONS 37 9.51e-01 0.005880 0.99000
REACTOME DISEASES OF MISMATCH REPAIR MMR 5 9.51e-01 -0.015900 0.99000
REACTOME SENSORY PERCEPTION OF TASTE 47 9.51e-01 0.005150 0.99000
REACTOME FGFR1C LIGAND BINDING AND ACTIVATION 11 9.52e-01 -0.010600 0.99000
REACTOME RND3 GTPASE CYCLE 41 9.53e-01 0.005330 0.99000
REACTOME PEROXISOMAL LIPID METABOLISM 28 9.55e-01 0.006170 0.99100
REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT 99 9.55e-01 -0.003290 0.99100
REACTOME SIGNALING BY WNT 318 9.55e-01 0.001820 0.99100
REACTOME FCERI MEDIATED CA 2 MOBILIZATION 30 9.56e-01 0.005830 0.99100
REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS 5 9.57e-01 -0.014000 0.99100
REACTOME RHOBTB GTPASE CYCLE 34 9.58e-01 0.005200 0.99100
REACTOME CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY 12 9.59e-01 -0.008610 0.99100
REACTOME SENSORY PERCEPTION OF SALTY TASTE 6 9.59e-01 -0.012100 0.99100
REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA 28 9.60e-01 -0.005450 0.99100
REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING 25 9.61e-01 0.005710 0.99100
REACTOME NEF MEDIATED CD8 DOWN REGULATION 7 9.61e-01 0.010700 0.99100
REACTOME DEADENYLATION OF MRNA 25 9.61e-01 -0.005620 0.99100
REACTOME DEGRADATION OF DVL 56 9.63e-01 -0.003610 0.99200
REACTOME PEXOPHAGY 11 9.63e-01 -0.008020 0.99200
REACTOME SIGNALING BY ERBB2 ECD MUTANTS 16 9.63e-01 0.006630 0.99200
REACTOME SYNTHESIS OF PE 13 9.65e-01 0.007120 0.99200
REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21 59 9.65e-01 0.003330 0.99200
REACTOME SUMOYLATION 179 9.66e-01 0.001870 0.99200
REACTOME TRANSCRIPTIONAL REGULATION BY MECP2 60 9.66e-01 0.003190 0.99200
REACTOME DEGRADATION OF AXIN 54 9.69e-01 0.003060 0.99400
REACTOME DCC MEDIATED ATTRACTIVE SIGNALING 14 9.70e-01 -0.005760 0.99500
REACTOME G2 PHASE 5 9.70e-01 0.009580 0.99500
REACTOME PCP CE PATHWAY 91 9.73e-01 -0.002080 0.99600
REACTOME CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2 11 9.76e-01 -0.005210 0.99800
REACTOME METALLOPROTEASE DUBS 36 9.77e-01 0.002820 0.99800
REACTOME E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS 58 9.77e-01 -0.002140 0.99800
REACTOME BETA DEFENSINS 27 9.78e-01 -0.003090 0.99800
REACTOME NEGATIVE REGULATION OF NOTCH4 SIGNALING 53 9.78e-01 0.002160 0.99800
REACTOME PI 3K CASCADE FGFR3 17 9.78e-01 0.003780 0.99800
REACTOME ARYL HYDROCARBON RECEPTOR SIGNALLING 6 9.79e-01 -0.006060 0.99800
REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION 16 9.80e-01 -0.003660 0.99800
REACTOME PI 3K CASCADE FGFR4 19 9.80e-01 -0.003320 0.99800
REACTOME PREVENTION OF PHAGOSOMAL LYSOSOMAL FUSION 9 9.81e-01 -0.004650 0.99800
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH PI3K 6 9.81e-01 0.005530 0.99800
REACTOME VITAMIN B1 THIAMIN METABOLISM 5 9.83e-01 0.005620 0.99800
REACTOME CALCINEURIN ACTIVATES NFAT 9 9.83e-01 -0.004180 0.99800
REACTOME P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1 6 9.84e-01 -0.004800 0.99800
REACTOMEMATURATION OF SARS COV 1 NUCLEOPROTEIN 11 9.84e-01 0.003530 0.99800
REACTOME CYTOCHROME C MEDIATED APOPTOTIC RESPONSE 12 9.85e-01 -0.003080 0.99900
REACTOME INACTIVATION OF CSF3 G CSF SIGNALING 25 9.85e-01 0.002110 0.99900
REACTOME OVARIAN TUMOR DOMAIN PROTEASES 36 9.86e-01 0.001650 0.99900
REACTOME SENSORY PROCESSING OF SOUND 72 9.87e-01 -0.001130 0.99900
REACTOME DOPAMINE RECEPTORS 5 9.87e-01 0.004220 0.99900
REACTOME PERK REGULATES GENE EXPRESSION 31 9.89e-01 0.001410 0.99900
REACTOME CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND 9 9.89e-01 0.002610 0.99900
REACTOME ANTIMICROBIAL PEPTIDES 76 9.90e-01 0.000816 0.99900
REACTOME TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN 13 9.91e-01 -0.001710 0.99900
REACTOME STAT3 NUCLEAR EVENTS DOWNSTREAM OF ALK SIGNALING 9 9.92e-01 -0.002030 0.99900
REACTOME RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA 27 9.92e-01 -0.001100 0.99900
REACTOME SCAVENGING BY CLASS B RECEPTORS 6 9.93e-01 0.002210 0.99900
REACTOME FASL CD95L SIGNALING 5 9.93e-01 -0.002350 0.99900
REACTOME ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS 11 9.93e-01 0.001450 0.99900
REACTOME CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION 24 9.94e-01 0.000834 0.99900
REACTOME TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS 26 9.95e-01 0.000693 0.99900
REACTOME SIGNALING BY ALK 26 9.95e-01 -0.000689 0.99900
REACTOME VEGF LIGAND RECEPTOR INTERACTIONS 7 9.96e-01 -0.001080 0.99900
REACTOME MISMATCH REPAIR 15 9.96e-01 0.000715 0.99900
REACTOME INTEGRIN SIGNALING 27 9.96e-01 -0.000509 0.99900
REACTOME TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE 39 9.97e-01 -0.000303 0.99900
REACTOME COSTIMULATION BY THE CD28 FAMILY 64 9.98e-01 -0.000211 0.99900
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS 5 9.98e-01 0.000636 0.99900
REACTOME ERKS ARE INACTIVATED 13 9.99e-01 0.000294 0.99900


Detailed Gene set reports



REACTOME_OLFACTORY_SIGNALING_PATHWAY

REACTOME_OLFACTORY_SIGNALING_PATHWAY
628
set REACTOME_OLFACTORY_SIGNALING_PATHWAY
setSize 348
pANOVA 6.18e-07
s.dist -0.156
p.adjustANOVA 0.00101



Top enriched genes

Top 20 genes
GeneID Gene Rank
OR5M8 -10256
OR7E24 -10235
OR10S1 -10088
OR2M7 -10084
OR13C4 -10083
OR10G8 -10080
OR8B8 -10056
OR10T2 -10028
OR1N1 -10012
OR1Q1 -9972
OR8H1 -9954
OR8K5 -9944
OR4K14 -9938
OR8B4 -9912
OR10H5 -9898
OR8B2 -9894
OR8I2 -9889
OR5J2 -9888
OR4X2 -9881
OR52N2 -9880

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
OR5M8 -10256.0
OR7E24 -10235.0
OR10S1 -10088.0
OR2M7 -10084.0
OR13C4 -10083.0
OR10G8 -10080.0
OR8B8 -10056.0
OR10T2 -10028.0
OR1N1 -10012.0
OR1Q1 -9972.0
OR8H1 -9954.0
OR8K5 -9944.0
OR4K14 -9938.0
OR8B4 -9912.0
OR10H5 -9898.0
OR8B2 -9894.0
OR8I2 -9889.0
OR5J2 -9888.0
OR4X2 -9881.0
OR52N2 -9880.0
OR8U3 -9879.0
OR10H1 -9820.0
OR51S1 -9819.0
OR51B6 -9809.0
OR9A4 -9750.0
OR2V1 -9749.0
OR4C46 -9709.0
OR10J1 -9707.0
OR52B2 -9697.0
OR56A4 -9638.0
OR5AC2 -9554.0
OR4N2 -9546.0
OR52H1 -9524.0
OR5M9 -9515.0
OR10J3 -9453.0
OR51G2 -9383.0
OR1L8 -9327.0
OR10G7 -9325.0
OR51L1 -9316.0
OR2AT4 -9314.0
OR1E1 -9313.0
OR6V1 -9304.0
OR8B12 -9284.0
OR7A10 -9280.0
OR5P3 -9256.0
OR8H3 -9226.0
OR6X1 -9223.0
OR56A5 -9214.0
OR6C74 -9213.0
OR6C70 -9206.0
OR2J2 -9134.0
OR1B1 -9126.0
OR9G4 -9081.0
OR56B4 -9046.0
OR52M1 -9031.0
OR52I1 -8992.0
OR10H3 -8991.0
OR9Q2 -8957.0
OR8A1 -8927.0
OR52A1 -8901.0
OR5H1 -8894.0
OR10G4 -8884.0
OR56A1 -8875.0
OR51V1 -8874.0
OR6C3 -8856.0
OR5T1 -8846.0
OR52E6 -8818.0
OR2C3 -8779.0
OR2M3 -8765.0
OR10A5 -8677.0
OR10G3 -8665.0
OR2AG2 -8648.0
OR56A3 -8627.0
OR10A4 -8624.0
OR6B1 -8611.0
OR1E2 -8595.0
OR2H2 -8582.0
OR10Z1 -8564.0
OR5M3 -8558.0
OR5M11 -8534.0
OR52D1 -8487.0
OR10V1 -8465.0
OR51E1 -8403.0
OR51D1 -8399.0
OR6C76 -8338.0
OR13J1 -8327.0
OR4D11 -8234.0
OR51I1 -8197.0
OR5T3 -8168.0
OR2A2 -8146.0
OR10A3 -8110.0
OR6C4 -8067.0
OR13C8 -7972.0
OR4M1 -7959.0
OR5AK2 -7906.0
OR11A1 -7870.0
OR8D2 -7842.0
OR4X1 -7749.0
OR8U8 -7741.0
ANO2 -7720.0
OR1F1 -7654.0
OR51I2 -7646.0
OR51B5 -7611.0
OR10P1 -7574.0
OR5A2 -7516.0
OR4C3 -7422.0
OR51T1 -7361.0
OR5B3 -7296.0
OR4D6 -7199.0
OR10C1 -7156.0
OR6K6 -7083.0
CNGB1 -7068.0
OR2AK2 -7061.0
OR6C6 -7051.0
OR4C12 -7013.0
OR7D4 -6998.0
OR2A14 -6910.0
GNG13 -6899.0
OR8S1 -6854.0
OR8D1 -6600.0
OR5P2 -6539.0
OR10A2 -6522.0
OR8K1 -6519.0
OR1J2 -6516.0
OR10A6 -6509.0
OR5K1 -6428.0
OR5A1 -6381.0
OR51B4 -6351.0
OR2B6 -6298.0
OR6T1 -6267.0
OR7A17 -6223.0
OR4D2 -6214.0
OR10X1 -6147.0
OR13D1 -6111.0
OR10AG1 -6082.0
OR51B2 -5720.0
OR5B2 -5718.0
OR10H2 -5684.0
OR9G1 -5562.5
OR9G9 -5562.5
OR6C68 -5286.0
OR11H6 -5162.0
OR2T1 -5040.0
OR13C3 -4991.0
OR10K2 -4969.0
OR1L1 -4873.0
OR6B3 -4817.0
OR3A3 -4732.0
OR4D10 -4652.0
OR5M10 -4628.0
OR10G2 -4621.0
OR2T4 -4571.0
OR2L2 -4542.0
OR5V1 -4448.0
OR5D16 -4434.0
OR4F6 -4296.0
OR10Q1 -4277.0
GNAL -4178.0
OR10K1 -3958.0
OR51Q1 -3880.0
OR9K2 -3795.0
OR5W2 -3731.0
OR51E2 -3723.0
OR5AU1 -3689.0
OR2L3 -3556.0
OR51A7 -3288.0
OR5AN1 -3099.0
OR2V2 -3056.0
OR2L8 -3021.0
OR2T6 -2982.0
OR1A2 -2910.0
OR13F1 -2851.0
OR52J3 -2480.0
OR6A2 -2325.0
OR8U1 -2290.0
OR5L1 -2208.0
OR5B12 -1953.0
OR2M4 -1949.0
REEP1 -1931.0
OR8D4 -1892.0
OR8J1 -1459.0
OR7D2 -1391.0
OR6C2 -1273.0
OR4F15 -876.0
EBF1 -867.0
OR4C45 -841.0
OR4C16 -821.0
OR2H1 -780.0
OR11H4 -758.0
OR2W3 -703.0
OR7C2 -486.0
OR6C75 -460.0
OR52W1 -421.0
OR3A1 -182.0
OR2B3 -117.0
OR4L1 79.0
RTP2 205.0
OR5C1 292.0
OR8G5 598.0
OR5AR1 604.0
OR6B2 654.0
OR1J4 779.0
LHX2 860.0
GNB1 949.0
OR5M1 1002.0
OR10W1 1039.0
OR1C1 1041.0
OR5L2 1204.0
OR2L13 1238.0
OR5B21 1327.0
OR12D2 1362.0
OR2S2 1575.0
OR4A15 1707.0
OR8G1 1778.0
OR2G3 1882.0
OR4A47 1901.0
OR9I1 2253.0
OR2K2 2293.0
OR1N2 2354.0
OR1G1 2434.0
OR2D3 2557.0
OR6C1 2602.0
OR10A7 2747.0
OR52E4 2814.0
OR51M1 2872.0
OR13G1 2993.0
OR2AG1 3026.0
OR5D18 3092.0
OR5AS1 3315.0
OR13A1 3320.0
OR2G6 3357.0
OR2D2 3692.0
OR5H2 3693.0
OR10H4 3729.0
OR52B6 3864.0
OR1A1 3973.0
OR2C1 4000.0
OR5D14 4032.0
OR52R1 4083.0
OR5K4 4251.0
OR7A5 4305.0
OR4B1 4341.0
LDB1 4486.0
OR4S1 4586.0
OR2F1 4595.0
OR8J3 4655.0
OR52I2 4663.0
OR7G2 4817.0
OR6N1 4964.0
OR4K1 5008.0
OR6Q1 5054.0
OR6F1 5091.0
ADCY3 5100.0
OR2L5 5103.0
OR6K2 5210.0
OR1S1 5282.0
OR1L3 5456.0
OR51F2 5548.0
OR2W1 5779.0
OR5I1 5796.0
OR10J5 5948.0
OR2M5 6181.0
OR1L6 6232.0
OR6Y1 6253.0
OR5T2 6380.0
OR2F2 6385.0
OR2T27 6479.0
OR2T12 6612.0
OR4K17 6692.0
OR7G1 6700.0
OR9Q1 6710.0
OR2Z1 6738.0
OR10G9 6803.0
OR5AP2 6833.0
OR11G2 6902.0
OR1S2 6968.0
OR5B17 7317.0
OR1M1 7547.0
OR2A12 7673.0
OR13C2 7727.0
OR5H6 7734.0
OR4K5 7761.0
OR12D3 7828.0
OR4D1 7891.0
OR2A5 7945.0
OR6P1 8099.0
OR8K3 8254.0
OR5K3 8391.0
OR52A5 8433.0
OR4C15 8446.0
OR6S1 8474.0
OR52K2 8560.0
OR6N2 8635.0
OR14I1 8721.0
OR52N1 8811.0
OR51F1 8934.0
OR1D2 9054.0
OR51A2 9081.0
OR6M1 9095.0
OR1L4 9140.0
OR52E8 9188.0
OR2B2 9194.0
OR2B11 9292.0
OR5H15 9329.0
OR4K2 9393.0
OR4E2 9395.0
OR14A16 9426.0
OR4N5 9533.0
OR9A2 9555.0
OR56B1 9577.0
OR2T11 9621.0
OR11L1 9630.0
OR6C65 9696.0
OR4A5 9774.0
OR7C1 9925.0
OR52K1 9985.0
OR51G1 9986.0
OR2T33 9992.0
OR4C6 9994.0
OR4D5 10078.0
OR1J1 10145.0
OR6K3 10271.0
OR5K2 10312.0
OR4K15 10322.0
OR52E2 10362.0
OR10AD1 10496.0
OR1K1 10520.0
OR13C9 10537.0
OR1I1 10583.0
OR14C36 10584.0
OR2T8 10663.0
OR14J1 10672.0
OR2T3 10702.0
OR2AP1 10849.0
CNGA4 10926.0
RTP1 10962.0
OR2Y1 10986.0
OR4K13 11011.0
OR2G2 11013.0
OR5F1 11016.0
OR2AE1 11034.0
OR3A2 11059.0
OR52L1 11381.0
OR4D9 11391.0
OR4A16 11491.0
OR7G3 11535.0
OR5D13 11539.0
OR2M2 11575.0


REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE

REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE
271
set REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE
setSize 105
pANOVA 2.83e-06
s.dist -0.264
p.adjustANOVA 0.00149



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL7A -9849.0
RPL13A -9727.5
RPLP0 -9534.0
RPS3A -9277.0
RPL17 -9227.0
SSR3 -9121.0
RPL3 -9097.0
RPL39L -8979.0
RPL29 -8969.0
SEC11C -8920.0
RPL7 -8910.0
RPS18 -8789.0
RPS2 -8633.0
RPSA -8411.0
RPL6 -8261.0
RPL34 -8230.0
RPS13 -8088.0
RPL14 -8070.0
RPS12 -7983.0
RPL23A -7919.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL7A -9849.0
RPL13A -9727.5
RPLP0 -9534.0
RPS3A -9277.0
RPL17 -9227.0
SSR3 -9121.0
RPL3 -9097.0
RPL39L -8979.0
RPL29 -8969.0
SEC11C -8920.0
RPL7 -8910.0
RPS18 -8789.0
RPS2 -8633.0
RPSA -8411.0
RPL6 -8261.0
RPL34 -8230.0
RPS13 -8088.0
RPL14 -8070.0
RPS12 -7983.0
RPL23A -7919.0
RPL4 -7750.0
RPS20 -7733.0
SEC61A1 -7652.0
RPS15A -7575.0
RPS15 -7544.0
RPL30 -7313.0
RPL13 -7308.0
RPS6 -7197.0
RPL10A -7183.0
RPL5 -7176.0
RPS27 -7155.0
RPS23 -7108.0
SEC61A2 -6293.0
RPS11 -5654.0
RPL18A -5504.0
RPS8 -5492.0
RPL27A -5422.0
SPCS1 -4942.0
RPL38 -4933.0
SRP19 -4841.0
SSR2 -4718.0
SRP54 -4704.0
SEC61B -4406.0
RPN2 -4357.0
RPL21 -4309.0
SEC61G -4173.0
SRP14 -4057.0
RPL11 -3914.0
RPL37 -3378.0
RPL28 -3334.0
RPL22 -3268.0
RPS10 -3097.0
RPL37A -2987.0
RPS28 -2923.0
RPS16 -2711.0
RPLP1 -2534.0
SRP72 -2457.0
RPL36AL -2415.5
RPLP2 -2271.0
RPS3 -2211.0
RPL12 -2033.0
SSR1 -1920.0
RPS14 -1898.0
RPL41 -1768.0
RPL9 -1624.0
UBA52 -1027.0
RPS27A -480.0
RPS19 -100.0
SPCS3 -78.0
RPL35A 155.0
RPL27 186.0
RPL31 415.0
RPL24 539.0
RPL22L1 834.0
RPL18 1008.0
SRP68 1474.0
SEC11A 2269.0
FAU 2277.0
RPS21 2323.0
RPL23 2439.0
RPS29 2769.0
RPL35 3004.0
SRPRB 3220.0
SRPRA 3307.0
RPS24 3487.0
RPS26 3565.0
RPL26L1 3578.0
RPL15 3621.0
RPS27L 3962.0
SPCS2 4119.0
RPS9 4613.0
DDOST 4789.0
RPS5 5602.0
RPS25 5728.0
RPL36 6037.0
RPL32 6039.0
RPL8 6252.0
RPS7 6408.0
RPN1 6502.0
RPL19 6666.0
RPL26 7892.0
TRAM1 9263.0
SRP9 10550.0
RPL10L 11201.0
RPL3L 11448.0


REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY

REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY
1486
set REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY
setSize 94
pANOVA 3.46e-06
s.dist -0.277
p.adjustANOVA 0.00149



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL7A -9849.0
RPL13A -9727.5
RPLP0 -9534.0
RPS3A -9277.0
RPL17 -9227.0
RPL3 -9097.0
RPL39L -8979.0
RPL29 -8969.0
RPL7 -8910.0
RPS18 -8789.0
ATF4 -8733.0
RPS2 -8633.0
RPSA -8411.0
RPL6 -8261.0
RPL34 -8230.0
RPS13 -8088.0
RPL14 -8070.0
RPS12 -7983.0
RPL23A -7919.0
RPL4 -7750.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL7A -9849.0
RPL13A -9727.5
RPLP0 -9534.0
RPS3A -9277.0
RPL17 -9227.0
RPL3 -9097.0
RPL39L -8979.0
RPL29 -8969.0
RPL7 -8910.0
RPS18 -8789.0
ATF4 -8733.0
RPS2 -8633.0
RPSA -8411.0
RPL6 -8261.0
RPL34 -8230.0
RPS13 -8088.0
RPL14 -8070.0
RPS12 -7983.0
RPL23A -7919.0
RPL4 -7750.0
RPS20 -7733.0
RPS15A -7575.0
RPS15 -7544.0
DDIT3 -7451.0
CEBPG -7401.0
RPL30 -7313.0
RPL13 -7308.0
RPS6 -7197.0
RPL10A -7183.0
RPL5 -7176.0
RPS27 -7155.0
RPS23 -7108.0
EIF2S2 -5983.0
RPS11 -5654.0
RPL18A -5504.0
RPS8 -5492.0
RPL27A -5422.0
RPL38 -4933.0
ATF2 -4821.0
GCN1 -4676.0
RPL21 -4309.0
ATF3 -3921.0
RPL11 -3914.0
RPL37 -3378.0
RPL28 -3334.0
RPL22 -3268.0
EIF2S1 -3113.0
RPS10 -3097.0
RPL37A -2987.0
RPS28 -2923.0
RPS16 -2711.0
RPLP1 -2534.0
RPL36AL -2415.5
RPLP2 -2271.0
RPS3 -2211.0
RPL12 -2033.0
RPS14 -1898.0
RPL41 -1768.0
RPL9 -1624.0
UBA52 -1027.0
RPS27A -480.0
RPS19 -100.0
RPL35A 155.0
RPL27 186.0
RPL31 415.0
RPL24 539.0
RPL22L1 834.0
RPL18 1008.0
FAU 2277.0
RPS21 2323.0
RPL23 2439.0
EIF2AK4 2676.0
RPS29 2769.0
ASNS 2773.0
RPL35 3004.0
RPS24 3487.0
RPS26 3565.0
RPL26L1 3578.0
RPL15 3621.0
RPS27L 3962.0
RPS9 4613.0
RPS5 5602.0
RPS25 5728.0
RPL36 6037.0
RPL32 6039.0
RPL8 6252.0
IMPACT 6337.0
RPS7 6408.0
RPL19 6666.0
RPL26 7892.0
CEBPB 7947.0
TRIB3 10209.0
RPL10L 11201.0
RPL3L 11448.0


REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION

REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION
151
set REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION
setSize 87
pANOVA 3.63e-06
s.dist -0.287
p.adjustANOVA 0.00149



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL7A -9849.0
RPL13A -9727.5
RPLP0 -9534.0
RPS3A -9277.0
RPL17 -9227.0
RPL3 -9097.0
RPL39L -8979.0
RPL29 -8969.0
RPL7 -8910.0
RPS18 -8789.0
RPS2 -8633.0
RPSA -8411.0
RPL6 -8261.0
RPL34 -8230.0
RPS13 -8088.0
RPL14 -8070.0
RPS12 -7983.0
RPL23A -7919.0
RPL4 -7750.0
RPS20 -7733.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL7A -9849.0
RPL13A -9727.5
RPLP0 -9534.0
RPS3A -9277.0
RPL17 -9227.0
RPL3 -9097.0
RPL39L -8979.0
RPL29 -8969.0
RPL7 -8910.0
RPS18 -8789.0
RPS2 -8633.0
RPSA -8411.0
RPL6 -8261.0
RPL34 -8230.0
RPS13 -8088.0
RPL14 -8070.0
RPS12 -7983.0
RPL23A -7919.0
RPL4 -7750.0
RPS20 -7733.0
RPS15A -7575.0
RPS15 -7544.0
RPL30 -7313.0
RPL13 -7308.0
EEF1B2 -7295.0
RPS6 -7197.0
RPL10A -7183.0
RPL5 -7176.0
RPS27 -7155.0
RPS23 -7108.0
RPS11 -5654.0
RPL18A -5504.0
RPS8 -5492.0
RPL27A -5422.0
EEF1A1 -5249.0
RPL38 -4933.0
EEF2 -4741.0
RPL21 -4309.0
RPL11 -3914.0
RPL37 -3378.0
RPL28 -3334.0
RPL22 -3268.0
EEF1G -3234.0
RPS10 -3097.0
RPL37A -2987.0
RPS28 -2923.0
RPS16 -2711.0
RPLP1 -2534.0
RPL36AL -2415.5
RPLP2 -2271.0
RPS3 -2211.0
RPL12 -2033.0
RPS14 -1898.0
RPL41 -1768.0
RPL9 -1624.0
UBA52 -1027.0
RPS27A -480.0
RPS19 -100.0
EEF1A2 153.0
RPL35A 155.0
RPL27 186.0
RPL31 415.0
RPL24 539.0
RPL22L1 834.0
RPL18 1008.0
FAU 2277.0
RPS21 2323.0
RPL23 2439.0
RPS29 2769.0
RPL35 3004.0
RPS24 3487.0
RPS26 3565.0
RPL26L1 3578.0
RPL15 3621.0
RPS27L 3962.0
RPS9 4613.0
RPS5 5602.0
RPS25 5728.0
RPL36 6037.0
RPL32 6039.0
RPL8 6252.0
RPS7 6408.0
RPL19 6666.0
RPL26 7892.0
EEF1D 10623.0
RPL10L 11201.0
RPL3L 11448.0


REACTOME_NONSENSE_MEDIATED_DECAY_NMD

REACTOME_NONSENSE_MEDIATED_DECAY_NMD
1443
set REACTOME_NONSENSE_MEDIATED_DECAY_NMD
setSize 107
pANOVA 1.43e-05
s.dist -0.243
p.adjustANOVA 0.0047



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL7A -9849.0
RPL13A -9727.5
RPLP0 -9534.0
RPS3A -9277.0
RPL17 -9227.0
ETF1 -9115.0
RPL3 -9097.0
RPL39L -8979.0
MAGOH -8971.0
RPL29 -8969.0
RPL7 -8910.0
RPS18 -8789.0
RPS2 -8633.0
RPSA -8411.0
PABPC1 -8320.0
RPL6 -8261.0
RPL34 -8230.0
RPS13 -8088.0
RPL14 -8070.0
RPS12 -7983.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL7A -9849.0
RPL13A -9727.5
RPLP0 -9534.0
RPS3A -9277.0
RPL17 -9227.0
ETF1 -9115.0
RPL3 -9097.0
RPL39L -8979.0
MAGOH -8971.0
RPL29 -8969.0
RPL7 -8910.0
RPS18 -8789.0
RPS2 -8633.0
RPSA -8411.0
PABPC1 -8320.0
RPL6 -8261.0
RPL34 -8230.0
RPS13 -8088.0
RPL14 -8070.0
RPS12 -7983.0
RPL23A -7919.0
RPL4 -7750.0
RPS20 -7733.0
RPS15A -7575.0
RPS15 -7544.0
RPL30 -7313.0
RPL13 -7308.0
RPS6 -7197.0
RPL10A -7183.0
RPL5 -7176.0
RPS27 -7155.0
RPS23 -7108.0
EIF4A3 -6771.0
GSPT1 -5954.0
RPS11 -5654.0
MAGOHB -5595.0
RPL18A -5504.0
RPS8 -5492.0
RPL27A -5422.0
RPL38 -4933.0
SMG8 -4599.0
RPL21 -4309.0
SMG1 -4243.0
RPL11 -3914.0
RBM8A -3566.0
RPL37 -3378.0
RPL28 -3334.0
RPL22 -3268.0
RPS10 -3097.0
RPL37A -2987.0
RPS28 -2923.0
PNRC2 -2838.0
SMG5 -2744.0
RPS16 -2711.0
RPLP1 -2534.0
RPL36AL -2415.5
RPLP2 -2271.0
RPS3 -2211.0
RPL12 -2033.0
DCP1A -1907.0
RPS14 -1898.0
RPL41 -1768.0
RPL9 -1624.0
UBA52 -1027.0
RPS27A -480.0
RPS19 -100.0
RPL35A 155.0
RPL27 186.0
NCBP2 209.0
RNPS1 270.0
RPL31 415.0
RPL24 539.0
SMG9 829.0
RPL22L1 834.0
RPL18 1008.0
PPP2R1A 1350.0
NCBP1 1937.0
FAU 2277.0
RPS21 2323.0
RPL23 2439.0
RPS29 2769.0
PPP2CA 2966.0
RPL35 3004.0
UPF3A 3046.0
RPS24 3487.0
RPS26 3565.0
RPL26L1 3578.0
RPL15 3621.0
RPS27L 3962.0
SMG7 4612.0
RPS9 4613.0
PPP2R2A 5566.0
RPS5 5602.0
RPS25 5728.0
UPF2 5823.0
RPL36 6037.0
RPL32 6039.0
SMG6 6176.0
RPL8 6252.0
RPS7 6408.0
RPL19 6666.0
UPF1 6809.0
RPL26 7892.0
CASC3 9037.0
EIF4G1 9917.0
RPL10L 11201.0
RPL3L 11448.0


REACTOME_INFLUENZA_INFECTION

REACTOME_INFLUENZA_INFECTION
228
set REACTOME_INFLUENZA_INFECTION
setSize 149
pANOVA 2.14e-05
s.dist -0.202
p.adjustANOVA 0.00579



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL7A -9849.0
RPL13A -9727.5
RPLP0 -9534.0
RPS3A -9277.0
RPL17 -9227.0
RPL3 -9097.0
RPL39L -8979.0
RPL29 -8969.0
RPL7 -8910.0
RPS18 -8789.0
RPS2 -8633.0
RPSA -8411.0
NUP153 -8270.0
RPL6 -8261.0
RPL34 -8230.0
RPS13 -8088.0
RPL14 -8070.0
RPS12 -7983.0
RPL23A -7919.0
HSPA1A -7818.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL7A -9849.0
RPL13A -9727.5
RPLP0 -9534.0
RPS3A -9277.0
RPL17 -9227.0
RPL3 -9097.0
RPL39L -8979.0
RPL29 -8969.0
RPL7 -8910.0
RPS18 -8789.0
RPS2 -8633.0
RPSA -8411.0
NUP153 -8270.0
RPL6 -8261.0
RPL34 -8230.0
RPS13 -8088.0
RPL14 -8070.0
RPS12 -7983.0
RPL23A -7919.0
HSPA1A -7818.0
RPL4 -7750.0
RPS20 -7733.0
NUP155 -7615.0
NUP85 -7584.0
RPS15A -7575.0
RPS15 -7544.0
RPL30 -7313.0
RPL13 -7308.0
RPS6 -7197.0
RPL10A -7183.0
RPL5 -7176.0
RPS27 -7155.0
RPS23 -7108.0
NUP58 -7085.0
NUP107 -7034.0
ISG15 -6637.0
NUP50 -6545.0
RAN -6480.0
KPNA3 -6083.0
GRSF1 -5770.0
RPS11 -5654.0
NUP42 -5576.0
NUP35 -5516.0
RPL18A -5504.0
RPS8 -5492.0
RPL27A -5422.0
SEC13 -4988.0
TPR -4960.0
POLR2I -4956.0
POM121C -4951.0
RPL38 -4933.0
TGFB1 -4548.0
POLR2K -4538.0
RPL21 -4309.0
NUP160 -3961.0
RPL11 -3914.0
NUP88 -3614.0
RPL37 -3378.0
RPL28 -3334.0
RPL22 -3268.0
RPS10 -3097.0
NUP54 -3047.0
RPL37A -2987.0
RPS28 -2923.0
POLR2L -2825.0
RPS16 -2711.0
PARP1 -2583.0
XPO1 -2579.0
KPNA5 -2539.0
RPLP1 -2534.0
AAAS -2469.0
IPO5 -2419.0
RPL36AL -2415.5
RAE1 -2351.0
RPLP2 -2271.0
RPS3 -2211.0
POLR2E -2107.0
RPL12 -2033.0
RPS14 -1898.0
NDC1 -1880.0
POLR2C -1811.0
RPL41 -1768.0
RPL9 -1624.0
NUP205 -1548.0
NUP43 -1199.0
POLR2F -1111.0
UBA52 -1027.0
NUP210 -657.0
NUP133 -607.0
CPSF4 -555.0
RPS27A -480.0
POLR2H -398.0
NUP214 -368.0
KPNA4 -361.0
POM121 -315.0
RPS19 -100.0
CLTA -73.0
RPL35A 155.0
RPL27 186.0
RPL31 415.0
RPL24 539.0
RPL22L1 834.0
RPL18 1008.0
GTF2F1 1094.0
NUP98 1115.0
NUP188 1653.0
FAU 2277.0
RPS21 2323.0
NUP93 2330.0
RPL23 2439.0
HSP90AA1 2720.0
KPNA1 2724.0
RPS29 2769.0
POLR2G 2901.0
RPL35 3004.0
RPS24 3487.0
RPS26 3565.0
RPL26L1 3578.0
RPL15 3621.0
KPNA7 3959.0
RPS27L 3962.0
SEH1L 4151.0
RPS9 4613.0
POLR2A 4709.0
POLR2D 4911.0
CLTC 4928.0
KPNA2 4937.0
NUP62 5345.0
RPS5 5602.0
PABPN1 5695.0
RPS25 5728.0
RPL36 6037.0
RPL32 6039.0
RPL8 6252.0
RPS7 6408.0
GTF2F2 6588.0
KPNB1 6615.0
RPL19 6666.0
EIF2AK2 6831.0
RANBP2 6991.0
POLR2B 7360.0
RPL26 7892.0
CALR 8004.0
NUP37 9290.0
DNAJC3 10441.0
CANX 11175.0
RPL10L 11201.0
RPL3L 11448.0
POLR2J 11645.0


REACTOME_TRANSLATION

REACTOME_TRANSLATION
1152
set REACTOME_TRANSLATION
setSize 278
pANOVA 2.47e-05
s.dist -0.147
p.adjustANOVA 0.00579



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL7A -9849.0
RPL13A -9727.5
RPLP0 -9534.0
MRPS23 -9407.0
RPS3A -9277.0
RPL17 -9227.0
MRPL21 -9210.0
EIF4A2 -9131.0
SSR3 -9121.0
ETF1 -9115.0
RPL3 -9097.0
RPL39L -8979.0
RPL29 -8969.0
AIMP2 -8942.0
SEC11C -8920.0
RPL7 -8910.0
RPS18 -8789.0
MRPL45 -8734.0
RPS2 -8633.0
RPSA -8411.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL7A -9849.0
RPL13A -9727.5
RPLP0 -9534.0
MRPS23 -9407.0
RPS3A -9277.0
RPL17 -9227.0
MRPL21 -9210.0
EIF4A2 -9131.0
SSR3 -9121.0
ETF1 -9115.0
RPL3 -9097.0
RPL39L -8979.0
RPL29 -8969.0
AIMP2 -8942.0
SEC11C -8920.0
RPL7 -8910.0
RPS18 -8789.0
MRPL45 -8734.0
RPS2 -8633.0
RPSA -8411.0
MRPS35 -8396.0
PABPC1 -8320.0
RPL6 -8261.0
HARS2 -8232.0
RPL34 -8230.0
DARS2 -8115.0
RPS13 -8088.0
RPL14 -8070.0
RPS12 -7983.0
RPL23A -7919.0
EIF3M -7893.0
MRPL51 -7856.0
RPL4 -7750.0
RPS20 -7733.0
SEC61A1 -7652.0
MRPL24 -7589.0
RPS15A -7575.0
RPS15 -7544.0
PTCD3 -7454.0
MRPS22 -7434.0
RPL30 -7313.0
RPL13 -7308.0
EEF1B2 -7295.0
MRPL9 -7237.0
RPS6 -7197.0
EIF3K -7192.0
RPL10A -7183.0
RPL5 -7176.0
RPS27 -7155.0
RPS23 -7108.0
EEF1E1 -6933.0
MRPS18A -6795.0
MRPL17 -6597.0
MRPL42 -6556.0
MRPS25 -6512.0
MRPL41 -6394.0
MRPL39 -6390.0
OXA1L -6373.0
MRPS17 -6311.0
MRPL12 -6299.0
SEC61A2 -6293.0
GFM2 -6276.0
EIF2S2 -5983.0
GSPT1 -5954.0
EIF2B2 -5864.0
KARS1 -5679.0
RPS11 -5654.0
EIF2B4 -5625.0
MRPL32 -5527.0
RPL18A -5504.0
RPS8 -5492.0
MRPL46 -5485.0
YARS1 -5455.0
RPL27A -5422.0
TUFM -5410.0
EEF1A1 -5249.0
MRPL11 -5241.0
TARS1 -5158.0
MRPL47 -5155.0
MRPS27 -5021.0
SPCS1 -4942.0
RPL38 -4933.0
AARS1 -4927.0
SRP19 -4841.0
EEF2 -4741.0
SSR2 -4718.0
TSFM -4713.0
GARS1 -4708.0
SRP54 -4704.0
PPA1 -4644.0
MRPS11 -4642.0
SEC61B -4406.0
RPN2 -4357.0
RPL21 -4309.0
SEC61G -4173.0
SRP14 -4057.0
MRPL50 -4003.0
EIF5B -3950.0
RPL11 -3914.0
MRPS10 -3835.0
MTIF2 -3805.0
MRPS24 -3801.0
MRPL37 -3706.0
MRPS31 -3633.0
MRPS18C -3623.0
RPL37 -3378.0
RPL28 -3334.0
EIF4A1 -3282.0
RPL22 -3268.0
AURKAIP1 -3239.0
EEF1G -3234.0
EIF2S1 -3113.0
RPS10 -3097.0
MRPL53 -3015.0
MRPL30 -3009.0
RPL37A -2987.0
RARS2 -2970.0
RPS28 -2923.0
MRPL27 -2842.0
RPS16 -2711.0
MRPL57 -2681.0
MRPS21 -2633.0
APEH -2553.0
RPLP1 -2534.0
MRPL18 -2526.0
SRP72 -2457.0
RPL36AL -2415.5
RPLP2 -2271.0
AIMP1 -2232.0
RPS3 -2211.0
MARS2 -2113.0
MRPS33 -2074.0
RPL12 -2033.0
MRPL22 -2021.0
MRPS16 -1960.0
SSR1 -1920.0
RPS14 -1898.0
MRPS15 -1896.0
IARS2 -1787.0
RPL41 -1768.0
RPL9 -1624.0
MRPL15 -1499.0
MRPL10 -1277.0
EARS2 -1266.0
FARSB -1154.0
DAP3 -1095.0
MRPL49 -1091.0
UBA52 -1027.0
EIF3F -1009.0
HARS1 -754.0
RPS27A -480.0
MTIF3 -459.0
DARS1 -422.0
ERAL1 -308.0
TRMT112 -120.0
RPS19 -100.0
MRPL36 -84.0
SPCS3 -78.0
MRPS5 -2.0
MRPL13 4.0
MRPS34 48.0
CHCHD1 88.0
EIF5 103.0
EEF1A2 153.0
RPL35A 155.0
RPL27 186.0
RPL31 415.0
GADD45GIP1 511.0
RPL24 539.0
EIF3J 563.0
MRPL43 825.0
RPL22L1 834.0
MRPS30 988.0
RPL18 1008.0
MRPL33 1133.0
FARSA 1159.0
MRPL19 1216.0
MRPL52 1387.0
MRPL2 1405.0
EIF4E 1409.0
SRP68 1474.0
TARS2 1593.0
MRPS14 1596.0
PARS2 1606.0
EIF3L 1680.0
MTFMT 2056.0
EIF4EBP1 2120.0
FARS2 2140.0
SEC11A 2269.0
FAU 2277.0
MRRF 2280.0
MRPS12 2285.0
RPS21 2323.0
LARS1 2399.0
RPL23 2439.0
MTRF1L 2454.0
MRPL20 2466.0
EIF3B 2546.0
RPS29 2769.0
MRPL44 2929.0
RPL35 3004.0
MRPL28 3030.0
MARS1 3031.0
MRPL1 3110.0
SRPRB 3220.0
EIF2B5 3260.0
SRPRA 3307.0
RPS24 3487.0
RPS26 3565.0
RPL26L1 3578.0
RPL15 3621.0
SARS2 3625.0
MRPS26 3635.0
MRPL38 3644.0
RPS27L 3962.0
MRPL4 4031.0
SPCS2 4119.0
MRPS18B 4489.0
MRPS9 4577.0
RPS9 4613.0
DDOST 4789.0
EIF3A 4912.0
MRPL14 4998.0
MRPS2 5033.0
EIF2B1 5154.0
YARS2 5251.0
EIF3H 5288.0
MRPS28 5295.0
EPRS1 5374.0
IARS1 5379.0
MRPL3 5390.0
MRPL34 5452.0
WARS2 5536.0
N6AMT1 5574.0
RPS5 5602.0
RPS25 5728.0
LARS2 5832.0
GFM1 5892.0
RPL36 6037.0
RPL32 6039.0
VARS2 6120.0
MRPL54 6125.0
RPL8 6252.0
EIF3E 6272.0
WARS1 6351.0
MRPL35 6390.0
RPS7 6408.0
EIF3G 6419.0
RPN1 6502.0
NARS2 6514.0
RPL19 6666.0
MRPS7 6682.0
MRPL58 6834.0
EIF4H 7802.0
RPL26 7892.0
MRPS6 8050.0
MRPL23 8081.0
VARS1 8171.0
EIF2B3 8233.0
MRPL16 8365.0
EIF4B 8380.0
CARS1 8554.0
NARS1 8700.0
MRPL48 8802.0
RARS1 8900.0
AARS2 9065.0
TRAM1 9263.0
MRPL40 9456.0
MRPL55 9786.0
EIF4G1 9917.0
EIF3I 9979.0
CARS2 10046.0
PPA2 10286.0
SRP9 10550.0
EIF3D 10575.0
EEF1D 10623.0
RPL10L 11201.0
RPL3L 11448.0


REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS

REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS
1364
set REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS
setSize 161
pANOVA 4.26e-05
s.dist -0.187
p.adjustANOVA 0.00874



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL7A -9849.0
RPL13A -9727.5
RPLP0 -9534.0
RPS3A -9277.0
RPL17 -9227.0
ETF1 -9115.0
RPL3 -9097.0
RPL39L -8979.0
MAGOH -8971.0
RPL29 -8969.0
RPL7 -8910.0
RPS18 -8789.0
PSMC4 -8740.0
RPS2 -8633.0
PSMA2 -8439.0
RPSA -8411.0
PABPC1 -8320.0
RPL6 -8261.0
RPL34 -8230.0
MSI1 -8137.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL7A -9849.0
RPL13A -9727.5
RPLP0 -9534.0
RPS3A -9277.0
RPL17 -9227.0
ETF1 -9115.0
RPL3 -9097.0
RPL39L -8979.0
MAGOH -8971.0
RPL29 -8969.0
RPL7 -8910.0
RPS18 -8789.0
PSMC4 -8740.0
RPS2 -8633.0
PSMA2 -8439.0
RPSA -8411.0
PABPC1 -8320.0
RPL6 -8261.0
RPL34 -8230.0
MSI1 -8137.0
RPS13 -8088.0
RPL14 -8070.0
RPS12 -7983.0
RPL23A -7919.0
PSMB10 -7764.0
RPL4 -7750.0
RPS20 -7733.0
RPS15A -7575.0
RPS15 -7544.0
ELOB -7497.0
RPL30 -7313.0
RPL13 -7308.0
RPS6 -7197.0
RPL10A -7183.0
PSMB5 -7180.0
RPL5 -7176.0
RPS27 -7155.0
PSMB4 -7154.0
RPS23 -7108.0
EIF4A3 -6771.0
PSMA7 -6451.0
ROBO2 -6176.0
USP33 -6170.0
GSPT1 -5954.0
PSMB8 -5916.0
RPS11 -5654.0
MAGOHB -5595.0
RPL18A -5504.0
RPS8 -5492.0
RPL27A -5422.0
LHX4 -5214.0
PSMB1 -5095.0
PSMC1 -5059.0
ELOC -5058.0
ROBO1 -4949.0
RPL38 -4933.0
PSMC3 -4854.0
RPL21 -4309.0
PSMD5 -4134.0
SLIT1 -4071.0
RPL11 -3914.0
LHX9 -3856.0
PSMB11 -3754.0
RBM8A -3566.0
PSMB9 -3530.0
PSMB3 -3408.0
RPL37 -3378.0
PSMB6 -3363.0
RPL28 -3334.0
RPL22 -3268.0
RPS10 -3097.0
RPL37A -2987.0
RPS28 -2923.0
ISL1 -2868.0
UBB -2864.0
RPS16 -2711.0
RPLP1 -2534.0
PSMC6 -2500.0
RPL36AL -2415.5
RPLP2 -2271.0
RPS3 -2211.0
PSME2 -2193.0
RPL12 -2033.0
LHX3 -1927.0
RPS14 -1898.0
PSMD9 -1799.0
RPL41 -1768.0
RPL9 -1624.0
UBA52 -1027.0
PSMC5 -548.0
RPS27A -480.0
PSMB2 -277.0
PSMD7 -122.0
RPS19 -100.0
PSMA5 -94.0
RPL35A 155.0
RPL27 186.0
NCBP2 209.0
RNPS1 270.0
PSMD13 355.0
RPL31 415.0
RPL24 539.0
RPL22L1 834.0
LHX2 860.0
RPL18 1008.0
PSMD14 1026.0
ROBO3 1316.0
PSMA3 1531.0
SEM1 1800.0
NCBP1 1937.0
HOXA2 1942.0
SLIT2 2027.0
FAU 2277.0
RPS21 2323.0
PSME3 2340.0
RPL23 2439.0
CUL2 2477.0
RPS29 2769.0
RPL35 3004.0
UPF3A 3046.0
PSMF1 3071.0
PSME1 3146.0
RPS24 3487.0
RPS26 3565.0
RPL26L1 3578.0
RPL15 3621.0
PSMA4 3755.0
PSMD2 3775.0
PSMD8 3787.0
RPS27L 3962.0
PSMA1 4142.0
LDB1 4486.0
RPS9 4613.0
RBX1 4824.0
ZSWIM8 4922.0
RPS5 5602.0
RPS25 5728.0
UPF2 5823.0
PSME4 5861.0
RPL36 6037.0
RPL32 6039.0
PSMD6 6097.0
RPL8 6252.0
RPS7 6408.0
DAG1 6524.0
RPL19 6666.0
UBC 6789.0
PSMC2 7343.0
PSMD1 7599.0
RPL26 7892.0
PSMD11 8203.0
PSMB7 8791.0
PSMD3 8951.0
CASC3 9037.0
PSMD12 9401.0
PSMA6 9410.0
PSMD4 9855.0
EIF4G1 9917.0
PSMA8 10830.0
RPL10L 11201.0
RPL3L 11448.0


REACTOME_SELENOAMINO_ACID_METABOLISM

REACTOME_SELENOAMINO_ACID_METABOLISM
484
set REACTOME_SELENOAMINO_ACID_METABOLISM
setSize 108
pANOVA 0.000164
s.dist -0.21
p.adjustANOVA 0.0299



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL7A -9849.0
RPL13A -9727.5
RPLP0 -9534.0
RPS3A -9277.0
RPL17 -9227.0
RPL3 -9097.0
RPL39L -8979.0
RPL29 -8969.0
AIMP2 -8942.0
RPL7 -8910.0
RPS18 -8789.0
RPS2 -8633.0
INMT -8435.0
RPSA -8411.0
RPL6 -8261.0
RPL34 -8230.0
RPS13 -8088.0
RPL14 -8070.0
RPS12 -7983.0
RPL23A -7919.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL7A -9849.0
RPL13A -9727.5
RPLP0 -9534.0
RPS3A -9277.0
RPL17 -9227.0
RPL3 -9097.0
RPL39L -8979.0
RPL29 -8969.0
AIMP2 -8942.0
RPL7 -8910.0
RPS18 -8789.0
RPS2 -8633.0
INMT -8435.0
RPSA -8411.0
RPL6 -8261.0
RPL34 -8230.0
RPS13 -8088.0
RPL14 -8070.0
RPS12 -7983.0
RPL23A -7919.0
RPL4 -7750.0
RPS20 -7733.0
RPS15A -7575.0
RPS15 -7544.0
RPL30 -7313.0
RPL13 -7308.0
RPS6 -7197.0
RPL10A -7183.0
RPL5 -7176.0
RPS27 -7155.0
RPS23 -7108.0
EEF1E1 -6933.0
KARS1 -5679.0
RPS11 -5654.0
RPL18A -5504.0
RPS8 -5492.0
RPL27A -5422.0
RPL38 -4933.0
SEPSECS -4720.0
RPL21 -4309.0
RPL11 -3914.0
PSTK -3462.0
RPL37 -3378.0
RPL28 -3334.0
RPL22 -3268.0
RPS10 -3097.0
RPL37A -2987.0
RPS28 -2923.0
PAPSS2 -2904.0
RPS16 -2711.0
RPLP1 -2534.0
SCLY -2493.0
RPL36AL -2415.5
RPLP2 -2271.0
AIMP1 -2232.0
RPS3 -2211.0
RPL12 -2033.0
RPS14 -1898.0
RPL41 -1768.0
RPL9 -1624.0
UBA52 -1027.0
RPS27A -480.0
DARS1 -422.0
RPS19 -100.0
RPL35A 155.0
RPL27 186.0
RPL31 415.0
MAT1A 493.0
RPL24 539.0
TXNRD1 670.0
RPL22L1 834.0
RPL18 1008.0
AHCY 1370.0
FAU 2277.0
RPS21 2323.0
LARS1 2399.0
RPL23 2439.0
CTH 2502.0
RPS29 2769.0
RPL35 3004.0
GNMT 3018.0
MARS1 3031.0
RPS24 3487.0
RPS26 3565.0
RPL26L1 3578.0
RPL15 3621.0
RPS27L 3962.0
SEPHS2 4122.0
RPS9 4613.0
NNMT 5218.0
EEFSEC 5361.0
EPRS1 5374.0
IARS1 5379.0
RPS5 5602.0
PAPSS1 5647.0
RPS25 5728.0
RPL36 6037.0
RPL32 6039.0
RPL8 6252.0
RPS7 6408.0
RPL19 6666.0
GSR 7221.0
HNMT 7294.0
RPL26 7892.0
RARS1 8900.0
SECISBP2 9073.0
RPL10L 11201.0
RPL3L 11448.0


REACTOME_EUKARYOTIC_TRANSLATION_INITIATION

REACTOME_EUKARYOTIC_TRANSLATION_INITIATION
1149
set REACTOME_EUKARYOTIC_TRANSLATION_INITIATION
setSize 110
pANOVA 0.000199
s.dist -0.205
p.adjustANOVA 0.0322



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL7A -9849.0
RPL13A -9727.5
RPLP0 -9534.0
RPS3A -9277.0
RPL17 -9227.0
EIF4A2 -9131.0
RPL3 -9097.0
RPL39L -8979.0
RPL29 -8969.0
RPL7 -8910.0
RPS18 -8789.0
RPS2 -8633.0
RPSA -8411.0
PABPC1 -8320.0
RPL6 -8261.0
RPL34 -8230.0
RPS13 -8088.0
RPL14 -8070.0
RPS12 -7983.0
RPL23A -7919.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL7A -9849.0
RPL13A -9727.5
RPLP0 -9534.0
RPS3A -9277.0
RPL17 -9227.0
EIF4A2 -9131.0
RPL3 -9097.0
RPL39L -8979.0
RPL29 -8969.0
RPL7 -8910.0
RPS18 -8789.0
RPS2 -8633.0
RPSA -8411.0
PABPC1 -8320.0
RPL6 -8261.0
RPL34 -8230.0
RPS13 -8088.0
RPL14 -8070.0
RPS12 -7983.0
RPL23A -7919.0
EIF3M -7893.0
RPL4 -7750.0
RPS20 -7733.0
RPS15A -7575.0
RPS15 -7544.0
RPL30 -7313.0
RPL13 -7308.0
RPS6 -7197.0
EIF3K -7192.0
RPL10A -7183.0
RPL5 -7176.0
RPS27 -7155.0
RPS23 -7108.0
EIF2S2 -5983.0
EIF2B2 -5864.0
RPS11 -5654.0
EIF2B4 -5625.0
RPL18A -5504.0
RPS8 -5492.0
RPL27A -5422.0
RPL38 -4933.0
RPL21 -4309.0
EIF5B -3950.0
RPL11 -3914.0
RPL37 -3378.0
RPL28 -3334.0
EIF4A1 -3282.0
RPL22 -3268.0
EIF2S1 -3113.0
RPS10 -3097.0
RPL37A -2987.0
RPS28 -2923.0
RPS16 -2711.0
RPLP1 -2534.0
RPL36AL -2415.5
RPLP2 -2271.0
RPS3 -2211.0
RPL12 -2033.0
RPS14 -1898.0
RPL41 -1768.0
RPL9 -1624.0
UBA52 -1027.0
EIF3F -1009.0
RPS27A -480.0
RPS19 -100.0
EIF5 103.0
RPL35A 155.0
RPL27 186.0
RPL31 415.0
RPL24 539.0
EIF3J 563.0
RPL22L1 834.0
RPL18 1008.0
EIF4E 1409.0
EIF3L 1680.0
EIF4EBP1 2120.0
FAU 2277.0
RPS21 2323.0
RPL23 2439.0
EIF3B 2546.0
RPS29 2769.0
RPL35 3004.0
EIF2B5 3260.0
RPS24 3487.0
RPS26 3565.0
RPL26L1 3578.0
RPL15 3621.0
RPS27L 3962.0
RPS9 4613.0
EIF3A 4912.0
EIF2B1 5154.0
EIF3H 5288.0
RPS5 5602.0
RPS25 5728.0
RPL36 6037.0
RPL32 6039.0
RPL8 6252.0
EIF3E 6272.0
RPS7 6408.0
EIF3G 6419.0
RPL19 6666.0
EIF4H 7802.0
RPL26 7892.0
EIF2B3 8233.0
EIF4B 8380.0
EIF4G1 9917.0
EIF3I 9979.0
EIF3D 10575.0
RPL10L 11201.0
RPL3L 11448.0


REACTOME_SENSORY_PERCEPTION

REACTOME_SENSORY_PERCEPTION
1581
set REACTOME_SENSORY_PERCEPTION
setSize 555
pANOVA 0.000215
s.dist -0.0918
p.adjustANOVA 0.0322



Top enriched genes

Top 20 genes
GeneID Gene Rank
OR5M8 -10256
OR7E24 -10235
OR10S1 -10088
OR2M7 -10084
OR13C4 -10083
OR10G8 -10080
TAS2R39 -10069
OR8B8 -10056
OR10T2 -10028
OR1N1 -10012
OR1Q1 -9972
OR8H1 -9954
OR8K5 -9944
OR4K14 -9938
OR8B4 -9912
OR10H5 -9898
OR8B2 -9894
OR8I2 -9889
OR5J2 -9888
OR4X2 -9881

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
OR5M8 -10256.0
OR7E24 -10235.0
OR10S1 -10088.0
OR2M7 -10084.0
OR13C4 -10083.0
OR10G8 -10080.0
TAS2R39 -10069.0
OR8B8 -10056.0
OR10T2 -10028.0
OR1N1 -10012.0
OR1Q1 -9972.0
OR8H1 -9954.0
OR8K5 -9944.0
OR4K14 -9938.0
OR8B4 -9912.0
OR10H5 -9898.0
OR8B2 -9894.0
OR8I2 -9889.0
OR5J2 -9888.0
OR4X2 -9881.0
OR52N2 -9880.0
OR8U3 -9879.0
TAS2R41 -9873.0
GNAT1 -9841.0
RHO -9825.0
OR10H1 -9820.0
OR51S1 -9819.0
OR51B6 -9809.0
STRC -9770.0
TAS2R16 -9762.0
OR9A4 -9750.0
OR2V1 -9749.0
OR4C46 -9709.0
OR10J1 -9707.0
OR52B2 -9697.0
RBP3 -9682.0
OTOP1 -9654.0
OR56A4 -9638.0
RBP2 -9636.0
AKR1B10 -9632.0
OR5AC2 -9554.0
OR4N2 -9546.0
OR52H1 -9524.0
OR5M9 -9515.0
OR10J3 -9453.0
OR51G2 -9383.0
OR1L8 -9327.0
OR10G7 -9325.0
OR51L1 -9316.0
OR2AT4 -9314.0
OR1E1 -9313.0
OR6V1 -9304.0
TAS2R1 -9289.0
OR8B12 -9284.0
OR7A10 -9280.0
GRXCR1 -9274.0
OR5P3 -9256.0
OR8H3 -9226.0
OR6X1 -9223.0
OR56A5 -9214.0
OR6C74 -9213.0
OR6C70 -9206.0
OR2J2 -9134.0
OR1B1 -9126.0
OR9G4 -9081.0
OR56B4 -9046.0
OR52M1 -9031.0
OR52I1 -8992.0
OR10H3 -8991.0
OR9Q2 -8957.0
OR8A1 -8927.0
OR52A1 -8901.0
OR5H1 -8894.0
OR10G4 -8884.0
OR56A1 -8875.0
OR51V1 -8874.0
OR6C3 -8856.0
OR5T1 -8846.0
OR52E6 -8818.0
TAS2R5 -8812.0
OR2C3 -8779.0
OR2M3 -8765.0
OR10A5 -8677.0
OR10G3 -8665.0
OR2AG2 -8648.0
RDH8 -8640.0
OR56A3 -8627.0
OR10A4 -8624.0
APOA2 -8623.0
FSCN2 -8614.0
OR6B1 -8611.0
OR1E2 -8595.0
OR2H2 -8582.0
TAS1R2 -8575.0
OR10Z1 -8564.0
OR5M3 -8558.0
OR5M11 -8534.0
OR52D1 -8487.0
OR10V1 -8465.0
OR51E1 -8403.0
OR51D1 -8399.0
TAS2R31 -8362.0
OR6C76 -8338.0
OR13J1 -8327.0
OR4D11 -8234.0
OR51I1 -8197.0
OR5T3 -8168.0
OR2A2 -8146.0
OR10A3 -8110.0
OR6C4 -8067.0
LRP10 -7998.0
OR13C8 -7972.0
OR4M1 -7959.0
OPN1SW -7940.0
OR5AK2 -7906.0
OR11A1 -7870.0
FNTA -7851.0
OR8D2 -7842.0
OR4X1 -7749.0
OR8U8 -7741.0
ANO2 -7720.0
OR1F1 -7654.0
OR51I2 -7646.0
OR51B5 -7611.0
OR10P1 -7574.0
OR5A2 -7516.0
PNLIP -7458.0
OR4C3 -7422.0
RDH16 -7372.0
OR51T1 -7361.0
OR5B3 -7296.0
CTBP2 -7282.0
USH1C -7220.0
OR4D6 -7199.0
GNGT1 -7193.0
SCN3A -7184.0
TTR -7178.0
OR10C1 -7156.0
TAS2R20 -7152.0
OR6K6 -7083.0
CNGB1 -7068.0
APOC2 -7065.0
OR2AK2 -7061.0
OR6C6 -7051.0
OR4C12 -7013.0
OR7D4 -6998.0
CIB2 -6919.0
OR2A14 -6910.0
GNG13 -6899.0
OR8S1 -6854.0
KCNMA1 -6772.0
GPIHBP1 -6750.0
OR8D1 -6600.0
OR5P2 -6539.0
OR10A2 -6522.0
OR8K1 -6519.0
OR1J2 -6516.0
OR10A6 -6509.0
OR5K1 -6428.0
OR5A1 -6381.0
OR51B4 -6351.0
OR2B6 -6298.0
SDC2 -6280.0
OR6T1 -6267.0
SCNN1D -6235.0
OR7A17 -6223.0
OR4D2 -6214.0
OR10X1 -6147.0
OR13D1 -6111.0
OR10AG1 -6082.0
PCLO -5926.0
RPE65 -5924.0
NMT2 -5780.0
OR51B2 -5720.0
OR5B2 -5718.0
OR10H2 -5684.0
OR9G1 -5562.5
OR9G9 -5562.5
SCNN1B -5355.0
OR6C68 -5286.0
TRPM4 -5285.0
OR11H6 -5162.0
KCNN2 -5109.0
TWF2 -5057.0
OR2T1 -5040.0
OR13C3 -4991.0
OR10K2 -4969.0
GPC6 -4967.0
OR1L1 -4873.0
APOA1 -4864.0
OR6B3 -4817.0
OR3A3 -4732.0
OR4D10 -4652.0
OR5M10 -4628.0
OR10G2 -4621.0
SCN9A -4608.0
OR2T4 -4571.0
OR2L2 -4542.0
AKR1C1 -4526.0
OR5V1 -4448.0
OR5D16 -4434.0
RDH10 -4336.0
GPC5 -4302.0
OR4F6 -4296.0
METAP1 -4279.0
OR10Q1 -4277.0
USH1G -4269.0
GNAL -4178.0
ESPNL -4145.0
MYO3B -3981.0
CABP2 -3977.0
OR10K1 -3958.0
SNAP25 -3916.0
APOE -3881.0
OR51Q1 -3880.0
XIRP2 -3847.0
OR9K2 -3795.0
OR5W2 -3731.0
OR51E2 -3723.0
LRP1 -3720.0
OR5AU1 -3689.0
SDC1 -3594.0
OR2L3 -3556.0
EPB41L3 -3532.0
PCDH15 -3485.0
SLC24A1 -3372.0
STRA6 -3294.0
OR51A7 -3288.0
LHFPL5 -3182.0
OR5AN1 -3099.0
OR2V2 -3056.0
RETSAT -3042.0
OR2L8 -3021.0
OR2T6 -2982.0
CACNB2 -2947.0
OR1A2 -2910.0
HSD17B1 -2905.0
OR13F1 -2851.0
CHRNA10 -2797.0
TMC1 -2767.0
SCNN1G -2654.0
TAS2R3 -2605.0
GPC1 -2599.0
OR52J3 -2480.0
CAPZB -2404.0
ESPN -2372.0
GRM4 -2344.0
OR6A2 -2325.0
OR8U1 -2290.0
GRM1 -2244.0
RIPOR2 -2218.0
OR5L1 -2208.0
TAS2R46 -2176.0
OR5B12 -1953.0
OR2M4 -1949.0
REEP1 -1931.0
OR8D4 -1892.0
MYO15A -1698.0
EPB41L1 -1653.0
RBP1 -1649.0
LRP2 -1541.0
CLIC5 -1524.0
SLC26A5 -1514.0
OTOG -1500.0
OR8J1 -1459.0
OR7D2 -1391.0
RGS9BP -1298.0
OR6C2 -1273.0
SCN2B -1228.0
TPRN -1086.0
LRP12 -1028.0
HSPG2 -1015.0
ATP2B2 -946.0
OR4F15 -876.0
EBF1 -867.0
OR4C45 -841.0
OR4C16 -821.0
GNAT3 -818.0
MYH9 -803.0
OR2H1 -780.0
OR11H4 -758.0
OR2W3 -703.0
OR7C2 -486.0
OR6C75 -460.0
OR52W1 -421.0
PJVK -203.0
OR3A1 -182.0
OR2B3 -117.0
OR4L1 79.0
ABCA4 102.0
SCNN1A 197.0
RTP2 205.0
OR5C1 292.0
APOM 312.0
EPS8 531.0
OR8G5 598.0
OR5AR1 604.0
OR6B2 654.0
MYO1C 777.0
OR1J4 779.0
GRXCR2 814.0
LHX2 860.0
GNB1 949.0
PLCB2 964.0
BSN 1000.0
OR5M1 1002.0
CAPZA1 1005.0
CACNA2D2 1022.0
OR10W1 1039.0
OR1C1 1041.0
OR5L2 1204.0
OR2L13 1238.0
OR5B21 1327.0
OR12D2 1362.0
NMT1 1419.0
RBP4 1444.0
CAMKMT 1484.0
OTOF 1499.0
OR2S2 1575.0
TWF1 1615.0
AKR1C4 1626.0
OR4A15 1707.0
GUCA1A 1731.0
OR8G1 1778.0
CAPZA2 1873.0
OR2G3 1882.0
OR4A47 1901.0
STX1A 1973.0
CABP1 2156.0
FNTB 2237.0
OR9I1 2253.0
APOB 2258.0
GUCY2D 2266.0
OR2K2 2293.0
OR1N2 2354.0
SCN2A 2359.0
OR1G1 2434.0
EZR 2494.0
OR2D3 2557.0
OR6C1 2602.0
RAB3A 2636.0
CACNA1D 2640.0
RDH12 2683.0
OR10A7 2747.0
OR52E4 2814.0
OR51M1 2872.0
OR13G1 2993.0
OR2AG1 3026.0
MYO7A 3074.0
OR5D18 3092.0
KCNJ2 3121.0
CDH23 3139.0
CYP4V2 3171.0
LRAT 3304.0
OR5AS1 3315.0
OR13A1 3320.0
OR2G6 3357.0
LDLR 3362.0
PLB1 3488.0
TRIOBP 3492.0
ACTG1 3513.0
TAS2R38 3553.0
RDX 3648.0
METAP2 3656.0
OR2D2 3692.0
OR5H2 3693.0
OR10H4 3729.0
GRK1 3844.0
OR52B6 3864.0
SPTBN1 3971.0
OR1A1 3973.0
SDC3 3991.0
OR2C1 4000.0
OR5D14 4032.0
PDE6B 4066.0
OR52R1 4083.0
PRKCQ 4146.0
ACTB 4173.0
OR5K4 4251.0
TAS2R8 4287.0
OR7A5 4305.0
SDC4 4317.0
OR4B1 4341.0
GRK4 4359.0
MYO3A 4483.0
LDB1 4486.0
OR4S1 4586.0
OR2F1 4595.0
RCVRN 4623.0
OR8J3 4655.0
OR52I2 4663.0
TAS2R7 4755.0
RLBP1 4775.0
OR7G2 4817.0
AKR1C3 4847.0
PLS1 4879.0
TAS2R43 4954.0
OR6N1 4964.0
OR4K1 5008.0
OR6Q1 5054.0
OR6F1 5091.0
ADCY3 5100.0
OR2L5 5103.0
LPL 5147.0
OR6K2 5210.0
OR1S1 5282.0
PRKCA 5314.0
LRRC52 5346.0
OR1L3 5456.0
OR51F2 5548.0
SPTAN1 5767.0
OR2W1 5779.0
OR5I1 5796.0
TMC2 5818.0
ITPR3 5878.0
OR10J5 5948.0
OR2M5 6181.0
OR1L6 6232.0
OR6Y1 6253.0
TAS2R50 6285.0
CALHM1 6289.0
DHRS3 6329.0
DNAJC5 6332.0
OR5T2 6380.0
OR2F2 6385.0
OR2T27 6479.0
GPC2 6530.0
OR2T12 6612.0
OR4K17 6692.0
OR7G1 6700.0
OR9Q1 6710.0
OR2Z1 6738.0
OR10G9 6803.0
OR5AP2 6833.0
OR11G2 6902.0
TRPM5 6958.0
OR1S2 6968.0
AGRN 7144.0
GUCA1C 7271.0
TAS2R14 7274.0
KCNMB1 7314.0
OR5B17 7317.0
SDR9C7 7401.0
APOC3 7482.0
OR1M1 7547.0
CNGA1 7607.0
OR2A12 7673.0
HSD17B6 7683.0
OR13C2 7727.0
OR5H6 7734.0
OR4K5 7761.0
OR12D3 7828.0
OR4D1 7891.0
OR2A5 7945.0
TAS2R40 7992.0
LRP8 8092.0
OR6P1 8099.0
OR8K3 8254.0
OR5K3 8391.0
WHRN 8406.0
CALM1 8425.0
OR52A5 8433.0
VAMP2 8445.0
OR4C15 8446.0
OR6S1 8474.0
RGS9 8555.0
OR52K2 8560.0
GRK7 8562.0
GNB3 8607.0
OR6N2 8635.0
TAS1R1 8637.0
GNB5 8701.0
OR14I1 8721.0
BCO2 8766.0
OTOGL 8792.0
OR52N1 8811.0
SLC17A8 8853.0
SCN1B 8909.0
OR51F1 8934.0
BCO1 8975.0
OR1D2 9054.0
OR51A2 9081.0
OR6M1 9095.0
OR1L4 9140.0
OR52E8 9188.0
OR2B2 9194.0
OR2B11 9292.0
OR5H15 9329.0
OR4K2 9393.0
OR4E2 9395.0
APOA4 9421.0
OR14A16 9426.0
NAPEPLD 9458.0
RDH11 9475.0
OR4N5 9533.0
OR9A2 9555.0
OR56B1 9577.0
PDE6A 9580.0
OR2T11 9621.0
OR11L1 9630.0
TAS2R30 9641.0
OR6C65 9696.0
EPS8L2 9719.0
SCN4B 9741.0
OR4A5 9774.0
ATP2B1 9852.0
OR7C1 9925.0
OR52K1 9985.0
OR51G1 9986.0
OR2T33 9992.0
OR4C6 9994.0
TMIE 10063.0
OR4D5 10078.0
OR1J1 10145.0
CHRNA9 10149.0
OR6K3 10271.0
OR5K2 10312.0
OR4K15 10322.0
OR52E2 10362.0
PDE6G 10437.0
GUCA1B 10493.0
OR10AD1 10496.0
OR1K1 10520.0
OR13C9 10537.0
GSN 10573.0
OR1I1 10583.0
OR14C36 10584.0
OR2T8 10663.0
OR14J1 10672.0
OR2T3 10702.0
TAS1R3 10746.0
OR2AP1 10849.0
DHRS9 10870.0
TAS2R13 10897.0
CNGA4 10926.0
RTP1 10962.0
OR2Y1 10986.0
OR4K13 11011.0
OR2G2 11013.0
OR5F1 11016.0
OR2AE1 11034.0
OR3A2 11059.0
SAG 11121.0
KCNQ4 11169.0
CALHM3 11225.0
RDH5 11232.0
OR52L1 11381.0
OR4D9 11391.0
TAS2R4 11464.0
CLPS 11481.0
OR4A16 11491.0
OR7G3 11535.0
OR5D13 11539.0
TAS2R10 11574.0
OR2M2 11575.0


REACTOME_INNATE_IMMUNE_SYSTEM

REACTOME_INNATE_IMMUNE_SYSTEM
227
set REACTOME_INNATE_IMMUNE_SYSTEM
setSize 1002
pANOVA 0.00079
s.dist 0.0627
p.adjustANOVA 0.102



Top enriched genes

Top 20 genes
GeneID Gene Rank
RNASE3 11676
ADGRE3 11615
CTSD 11577
TYROBP 11559
CCL22 11547
S100P 11522
SIRPA 11515
S100A8 11501
RNASE6 11487
CD300LB 11467
DOK3 11349
RNASE2 11331
CTSZ 11271
CD93 11230
TLR4 11228
RNASE7 11222
CXCR2 11211
CDA 11199
SLC11A1 11176
DEFB124 11097

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RNASE3 11676.0
ADGRE3 11615.0
CTSD 11577.0
TYROBP 11559.0
CCL22 11547.0
S100P 11522.0
SIRPA 11515.0
S100A8 11501.0
RNASE6 11487.0
CD300LB 11467.0
DOK3 11349.0
RNASE2 11331.0
CTSZ 11271.0
CD93 11230.0
TLR4 11228.0
RNASE7 11222.0
CXCR2 11211.0
CDA 11199.0
SLC11A1 11176.0
DEFB124 11097.0
CD180 11094.0
EPX 11062.0
SIRPB1 11046.0
TLR1 11039.0
PYCARD 10994.0
DEFA6 10987.0
ADGRG3 10980.0
AGPAT2 10977.0
RNF135 10972.0
TREX1 10969.0
S100A9 10944.0
MS4A2 10922.0
MAPK12 10899.0
PLEKHO2 10886.0
UBA7 10884.0
IFNA14 10848.0
SIGLEC15 10842.0
FCER1G 10833.0
PSMA8 10830.0
CLU 10819.0
S100A7 10792.0
TICAM2 10754.0
CYB5R3 10743.0
CLEC7A 10720.0
FCGR3A 10696.0
C3 10676.0
AZU1 10675.0
PGLYRP2 10671.0
CCL17 10630.0
C5AR2 10613.0
DEFB126 10596.0
TXNDC5 10576.0
GSN 10573.0
CLEC4A 10554.0
RELA 10539.0
WIPF3 10490.0
PRKACG 10488.0
CEACAM6 10474.0
DNAJC3 10441.0
C1orf35 10399.0
LYZ 10380.0
MNDA 10354.0
BPIFB2 10347.0
PRKACB 10345.0
CTSG 10335.0
SIGIRR 10330.0
GMFG 10257.0
P2RX1 10251.0
RHOG 10240.0
AMPD3 10238.0
CD300E 10235.0
FADD 10234.0
PRG2 10233.0
IFNA13 10215.0
CTSV 10179.0
CMTM6 10164.0
TRAF6 10162.0
MAP2K1 10138.0
PPBP 10136.0
NCR2 10127.0
DEFB128 10100.0
GSTP1 10098.0
CEACAM8 10069.0
ATP6V1E2 10030.0
SYNGR1 10010.0
IRAK2 9952.0
AGER 9946.0
DEFB118 9914.0
GRN 9908.0
TREM1 9883.0
PPP2R1B 9868.0
LRRFIP1 9863.0
PSMD4 9855.0
CPN2 9843.0
CD177 9842.0
RETN 9839.0
MS4A3 9821.0
PLD4 9718.0
ATP6V0D2 9714.0
LILRB2 9694.0
DUSP3 9676.0
RIGI 9640.0
AHSG 9623.0
PADI2 9599.0
TAB1 9549.0
CLEC10A 9548.0
B4GALT1 9547.0
SRC 9536.0
DBNL 9509.0
PLAUR 9497.0
SLC27A2 9483.0
PLA2G2A 9461.0
PSMA6 9410.0
PSMD12 9401.0
CASP4 9358.0
IL1B 9350.0
FGL2 9321.0
PIK3R2 9304.0
CLEC5A 9296.0
PDPK1 9291.0
TLR10 9280.0
PELI2 9276.0
LRRC14 9234.0
LYN 9232.0
FOS 9224.0
IFNA1 9218.0
MVP 9215.0
CFI 9210.0
SERPINB6 9161.0
CAT 9146.0
DEFA5 9123.0
DNM2 9121.0
NDUFC2 9101.0
FABP5 9079.0
RAB5C 9071.0
CDK13 9064.0
FCAR 9050.0
MAPK13 9034.0
RASGRP2 9028.0
ARG1 9022.0
N4BP1 8982.0
PSMD3 8951.0
KCNAB2 8939.0
FCGR2A 8938.0
DEFB127 8929.0
LCN2 8920.0
LPCAT1 8914.0
PTPRJ 8896.0
GPI 8883.0
WIPF1 8882.0
PELI3 8873.0
STBD1 8823.0
NLRP3 8816.0
NCKIPSD 8807.0
ATP6V0A1 8796.0
PSMB7 8791.0
RAC2 8775.0
TLR6 8756.0
RPS6KA1 8744.0
C8B 8743.0
LTA4H 8737.0
LY96 8736.0
PRDX6 8694.0
MYO5A 8690.0
CASP10 8685.0
CTSL 8681.0
NRAS 8673.0
CPN1 8640.0
MAP3K14 8634.0
MAP3K8 8624.0
PI3 8564.0
CAMP 8488.0
CALM1 8425.0
IRAK3 8381.0
SFTPA1 8350.0
MUC16 8322.0
NFKBIA 8320.0
HP 8269.0
BRK1 8230.0
DOCK2 8228.0
VCL 8223.0
PSMD11 8203.0
CLEC4E 8188.0
LAT2 8176.0
DGAT1 8141.0
HMGB1 8140.0
RIPK3 8116.0
GYG1 8098.0
SLCO4C1 8076.0
PLD3 8067.0
MBL2 8060.0
DYNC1H1 8043.0
ICAM2 8034.0
NLRC3 8028.0
TNFAIP6 8006.0
QSOX1 7995.0
PRKCD 7994.0
SARM1 7965.0
PTX3 7936.0
MYD88 7926.0
HGSNAT 7860.0
TLR9 7855.0
TNFAIP3 7851.0
FLG2 7830.0
OSTF1 7792.0
ECSIT 7762.0
S100A1 7756.0
RAB31 7723.0
DDX41 7719.0
ADA2 7679.0
CPB2 7665.0
COTL1 7645.0
ABI2 7617.0
PSMD1 7599.0
FCN3 7580.0
CRP 7548.0
PDXK 7522.0
ATP6V1E1 7510.0
CASP2 7503.0
SLC2A5 7493.0
CUL1 7485.0
PAFAH1B2 7472.0
DUSP6 7423.0
SERPINB1 7372.0
ELMO1 7363.0
MAP3K7 7351.0
TUBB4B 7350.0
PSMC2 7343.0
MUCL1 7342.0
S100B 7337.0
MUC21 7324.0
ATP6V0A4 7322.0
LAIR1 7299.0
NCF2 7254.0
ATG12 7253.0
VAT1 7237.0
IKBKB 7170.0
CTSK 7146.0
ALDOC 7091.0
PSTPIP1 7073.0
NBEAL2 7028.0
RAB3D 7017.0
GAB2 7008.0
NOS3 6930.0
PAK2 6918.0
AGL 6891.0
HMOX1 6881.0
CKAP4 6873.0
ABL1 6822.0
UBC 6789.0
ATP6V1G3 6755.0
SLC15A4 6751.0
DNM3 6749.0
CREB1 6748.0
MYO9B 6741.0
CDC42 6736.0
TAX1BP1 6633.0
PDAP1 6620.0
LAMTOR2 6616.0
KPNB1 6615.0
LGMN 6587.0
STK10 6583.0
ATP6V0A2 6577.0
ACTR1B 6575.0
FCER1A 6564.0
UBE2M 6559.0
MCEMP1 6546.0
DYNC1LI1 6503.0
HSPA6 6486.0
A1BG 6455.0
ATP6V0E1 6444.0
PNP 6437.0
CFH 6403.0
TRAF3 6357.0
ADAM10 6349.0
DNAJC5 6332.0
CYSTM1 6310.0
TRPM2 6308.0
LGALS3 6267.0
RPS6KA2 6218.0
BPIFA1 6203.0
POLR3B 6191.0
SERPINA1 6130.0
PSMD6 6097.0
SVIP 6091.0
C5 6051.0
MEF2A 6047.0
PTAFR 6018.0
RASGRP4 6005.0
NLRX1 6001.0
MEFV 5994.0
PLAU 5991.0
PPP3R1 5990.0
RNF216 5987.0
ITPR2 5971.0
MAPKAPK2 5929.0
DERA 5888.0
ITPR3 5878.0
ZBP1 5868.0
PSME4 5861.0
CREG1 5809.0
ACTR2 5785.0
NLRC5 5774.0
SPTAN1 5767.0
FGB 5732.0
CD14 5691.0
CD209 5679.0
PYGB 5674.0
RPS6KA5 5668.0
ATP6V1B2 5664.0
ATG7 5627.0
TOLLIP 5614.0
ATP6V0C 5600.0
UNC93B1 5582.0
CD44 5565.0
NOD2 5535.0
DNAJC13 5530.0
MAVS 5510.0
DEFB123 5467.0
SKP1 5453.0
ACTR3 5420.0
APP 5402.0
NME2 5353.0
LAMTOR1 5344.0
PPP3CA 5341.0
CAB39 5333.0
VNN1 5330.0
PLA2G6 5298.0
PIK3R1 5287.0
RAB7A 5275.0
ARHGAP45 5269.0
CARD11 5258.0
FCGR3B 5236.0
NCF4 5213.0
ATP6V0B 5204.0
FPR2 5159.0
ACAA1 5151.0
CD33 5139.0
UNC13D 5131.0
RAB24 5081.0
PAK1 5067.0
PSAP 5060.0
ALPK1 5014.0
RAP1A 4971.0
PIK3CB 4871.0
PLD2 4870.0
GZMM 4844.0
TIMP2 4800.0
DDOST 4789.0
IQGAP2 4762.0
BTRC 4739.0
LY86 4728.0
GM2A 4715.0
DEFB104A 4710.5
DEFB104B 4710.5
GALNS 4708.0
ITGAL 4696.0
MUC3A 4692.0
SLC44A2 4625.0
GLIPR1 4601.0
IFNA16 4593.0
TCN1 4551.0
C1QA 4464.0
PIN1 4453.0
MUC1 4381.0
AP2A2 4330.0
EP300 4318.0
POLR3C 4313.0
GRB2 4291.0
OLR1 4289.0
TIRAP 4274.0
PKM 4258.0
C5AR1 4242.0
CEACAM1 4237.0
MAPK9 4184.0
ACTB 4173.0
LPO 4149.0
MAP2K6 4147.0
PRKCQ 4146.0
PSMA1 4142.0
POLR3G 4134.0
STOM 4127.0
POLR1D 4118.0
ANXA2 4115.0
MAP2K3 4044.0
PGM2 3993.0
ARPC4 3955.0
ITPR1 3907.0
CNN2 3901.0
TRIM56 3892.0
VAPA 3811.0
TLR3 3799.0
GNS 3788.0
PSMD8 3787.0
CST3 3785.0
PSMD2 3775.0
PSMA4 3755.0
LEAP2 3666.0
LIMK1 3654.0
MAPK11 3652.0
PRKCE 3633.0
SDCBP 3607.0
MYO10 3546.0
HSP90AB1 3525.0
ACTG1 3513.0
HRNR 3499.0
TRIM32 3485.0
ARSB 3447.0
ATP6V0D1 3420.0
CHUK 3407.0
NLRC4 3400.0
PRKACA 3386.0
IFNA2 3369.0
RNF125 3335.0
NEU1 3330.0
IGF2R 3310.0
CD59 3309.0
CD58 3286.0
STK11IP 3282.0
COLEC10 3256.0
MIF 3247.0
NKIRAS1 3231.0
TP53 3222.0
CRISPLD2 3213.0
CREBBP 3198.0
SCAMP1 3189.0
GHDC 3185.0
CAP1 3180.0
CLEC6A 3151.0
PSME1 3146.0
MAPK8 3125.0
VAV3 3091.0
CD46 3078.0
BAIAP2 3072.0
PSMF1 3071.0
ATP8A1 3058.0
CPNE3 3041.0
YES1 3011.0
ATP11A 2989.0
ORM2 2980.0
PPP2CA 2966.0
WASL 2921.0
PGM1 2881.0
NHLRC3 2853.0
MLEC 2836.0
ADGRE5 2830.0
EEA1 2823.0
CAPN1 2788.0
MAP2K7 2784.0
HSP90AA1 2720.0
SERPING1 2719.0
CR1 2675.0
HTN1 2653.0
RAC1 2646.0
DPP7 2639.0
RAB3A 2636.0
TKFC 2622.0
BRI3 2604.0
DSN1 2595.0
DEFB116 2577.0
KCMF1 2455.0
LILRA3 2444.0
POLR3E 2411.0
ATP6V1H 2391.0
IMPDH1 2372.0
ATP6V1C2 2362.0
MUC17 2357.0
TRAPPC1 2352.0
HSP90B1 2344.0
PSME3 2340.0
SIGLEC14 2267.0
APOB 2258.0
IFNB1 2250.0
COMMD3 2222.0
TCIRG1 2220.0
KLRK1 2212.0
CD36 2158.0
BIN2 2118.0
CYFIP2 2117.0
DEFB133 2111.0
PTPN4 2079.0
TRAF2 2076.0
ARPC5 2012.0
HK3 2002.0
RAB37 2001.0
PFKL 1983.0
NF2 1978.0
NAPRT 1977.0
UBE2L6 1946.0
PRKDC 1936.0
FGR 1934.0
NCKAP1 1920.0
DEFB129 1919.0
CAPZA2 1873.0
BIRC2 1854.0
VPS35L 1810.0
SEM1 1800.0
VAV1 1771.0
P2RX7 1754.0
ATP8B4 1743.0
TMEM30A 1737.0
CCR2 1649.0
PYGL 1611.0
ARPC2 1597.0
CYFIP1 1580.0
PSMA3 1531.0
CTNNB1 1521.0
ALDOA 1448.0
PLD1 1425.0
ENPP4 1418.0
ANO6 1402.0
RAP1B 1389.0
ITLN1 1356.0
PPP2R1A 1350.0
STAT6 1343.0
REG3G 1335.0
POLR3D 1272.0
TEC 1231.0
CTSA 1193.0
DYNLL1 1174.0
ATP11B 1173.0
GPR84 1172.0
FTL 1149.0
CHI3L1 1131.0
TNFRSF1B 1098.0
NPC2 1093.0
C1S 1067.0
DIAPH1 1042.0
SNAP29 1035.0
PSMD14 1026.0
CAPZA1 1005.0
ABI1 994.0
VRK3 989.0
RELB 947.0
ALDH3B1 923.0
NFATC2 901.0
PRTN3 900.0
DEFB132 882.0
PLPP4 864.0
CTSH 826.0
MEF2C 824.0
CFB 793.0
MYO1C 777.0
RAB6A 772.0
VTN 748.0
MUC5B 738.0
SFTPD 737.0
ARSA 735.0
HSPA1B 667.0
ARMC8 614.0
NOS1 595.0
FTH1 565.0
MMP9 554.0
CCT8 535.0
NOD1 506.0
BCL2 491.0
GLB1 413.0
MASP2 402.0
PSMD13 355.0
COMMD9 319.0
PROS1 306.0
ATP6V1C1 253.0
CD81 170.0
CXCR1 119.0
ACLY 115.0
DHX58 100.0
MAP2K4 89.0
NCK1 75.0
IRF3 49.0
MUC6 47.0
MANBA 45.0
NFKBIB -11.0
ATG5 -13.0
PELI1 -80.0
PSMA5 -94.0
POLR1C -111.0
PSMD7 -122.0
PIK3C3 -141.0
CSNK2B -224.0
RAB10 -247.0
PPP2CB -251.0
PSMB2 -277.0
RHOF -279.0
OSCAR -291.0
MUC7 -298.0
PRKCSH -309.0
CD300A -311.0
IKBIP -352.0
ILF2 -353.0
CARD9 -366.0
RAP2B -390.0
POLR2H -398.0
UBE2D2 -405.0
DEFB113 -409.0
PLPP5 -450.0
GDI2 -477.0
RPS27A -480.0
ATP6V1B1 -492.0
WIPF2 -493.0
TMEM63A -495.0
MUC15 -524.0
MAPK1 -543.0
TBK1 -545.0
PSMC5 -548.0
C4BPA -603.0
ICAM3 -604.0
CFL1 -614.0
SOS1 -629.0
CASP9 -639.0
PANX1 -643.0
ARHGAP9 -774.0
NIT2 -776.0
MYH9 -803.0
USP14 -851.0
ACTR10 -878.0
GRAP2 -903.0
POLR3F -1002.0
ARPC3 -1026.0
UBA52 -1027.0
GGH -1041.0
C6orf120 -1045.0
SUGT1 -1073.0
PA2G4 -1078.0
NOS2 -1099.0
RNASE8 -1100.0
POLR2F -1111.0
DEFB119 -1161.0
BIRC3 -1208.0
SEMG1 -1221.0
PLCG2 -1234.0
WASF3 -1271.0
DSC1 -1272.0
MAPK7 -1333.0
IRF7 -1374.0
CLEC4C -1376.0
CTSS -1455.0
CHIT1 -1464.0
ORMDL3 -1465.0
LAMP1 -1480.0
XRCC6 -1507.0
ADAM8 -1525.0
GCA -1582.0
PLCG1 -1585.0
ERP44 -1612.0
NFASC -1619.0
DEFB1 -1631.0
PCBP2 -1632.0
SHC1 -1678.0
C2 -1690.0
AP1M1 -1704.0
CXCL1 -1721.0
KRT1 -1726.0
PSMD9 -1799.0
HVCN1 -1819.0
SNAP23 -1828.0
CPPED1 -1863.0
JUP -1895.0
DNM1 -1904.0
ATP6V1F -1916.0
DEFB125 -1929.0
SOCS1 -1940.0
ITCH -2019.0
CRACR2A -2053.0
TXN -2090.0
FBXW11 -2091.0
POLR2E -2107.0
ART1 -2142.0
WASF2 -2166.0
PSME2 -2193.0
ALOX5 -2212.0
PTPRN2 -2223.0
ARPC1B -2248.0
CLEC12A -2268.0
ELMO2 -2273.0
CPNE1 -2305.0
CD63 -2307.0
IDH1 -2367.0
S100A12 -2389.0
PTPRC -2396.0
CFD -2403.0
ATP6V0E2 -2424.0
ATP6V1A -2433.0
QPCT -2454.0
TAB2 -2478.0
PSMC6 -2500.0
RAB27A -2506.0
SIKE1 -2507.0
APEH -2553.0
LCP2 -2589.0
MUC12 -2623.0
FUCA1 -2628.0
ROCK1 -2637.0
CD47 -2673.0
MUC4 -2700.0
IRAG2 -2777.0
EPPIN -2823.0
POLR2L -2825.0
UBE2K -2845.0
TICAM1 -2846.0
UBB -2864.0
HEXB -2881.0
SIGLEC9 -2950.0
MGST1 -2964.0
MASP1 -2981.0
APAF1 -2983.0
DEFB136 -2992.0
CEP290 -3039.0
SURF4 -3058.0
NLRP1 -3062.0
MAP3K1 -3071.0
NFAM1 -3074.0
LCK -3095.0
HLA-A -3177.0
NFATC3 -3220.0
PIK3R4 -3265.0
PTK2 -3278.0
LRRC7 -3298.0
MPO -3302.0
NLRP4 -3352.0
NKIRAS2 -3355.0
PSMB6 -3363.0
MAN2B1 -3371.0
IRAK4 -3377.0
TOMM70 -3403.0
PSMB3 -3408.0
ASAH1 -3431.0
SERPINB12 -3438.0
MAPKAPK3 -3439.0
VAV2 -3491.0
UBR4 -3504.0
PSMB9 -3530.0
ITGAV -3555.0
NCSTN -3579.0
HERC5 -3604.0
PRCP -3639.0
DTX4 -3661.0
ARPC1A -3664.0
C7 -3668.0
DUSP4 -3669.0
CASP8 -3681.0
TUBB -3691.0
HPSE -3696.0
PPIA -3699.0
HCK -3712.0
PSMB11 -3754.0
XRCC5 -3809.0
SYK -3820.0
C1R -3849.0
DOCK1 -3854.0
C1QB -3907.0
SNAP25 -3916.0
ALAD -3926.0
GOLGA7 -3972.0
ATP6V1D -3979.0
RAB14 -3984.0
TLR2 -3985.0
JUN -4010.0
UBE2N -4015.0
CANT1 -4054.0
SRP14 -4057.0
ANPEP -4101.0
BCL10 -4111.0
MUC13 -4117.0
MAPK14 -4119.0
PSMD5 -4134.0
HSPA8 -4146.0
DUSP7 -4151.0
B2M -4170.0
RAF1 -4187.0
BPIFB6 -4201.0
TXK -4229.0
IST1 -4231.0
CTSC -4258.0
USP18 -4276.0
CD247 -4301.0
APRT -4305.0
HEBP2 -4367.0
GSDMD -4384.0
MME -4399.0
ATP6V1G1 -4404.0
TIFA -4463.0
PTPRB -4493.0
RASGRP1 -4502.0
DEFB121 -4513.0
POLR2K -4538.0
ATP6V1G2 -4540.0
AHCYL1 -4631.0
GAA -4665.0
RAB44 -4697.0
EEF2 -4741.0
FAF2 -4769.0
HRAS -4793.0
ATF2 -4821.0
CRK -4825.0
NFKB2 -4827.0
CD19 -4838.0
PSMC3 -4854.0
CFHR5 -4858.0
POLR3GL -4865.0
CSTB -4892.0
FOLR3 -4912.0
C1QC -4941.0
MUC20 -4950.0
BPIFB4 -4963.0
TRIM25 -4964.0
CCT2 -5010.0
IFNA6 -5028.0
TMBIM1 -5045.0
PSMC1 -5059.0
PSEN1 -5077.0
PSMB1 -5095.0
ITGAM -5118.0
TRIM21 -5133.0
POLR3A -5152.0
TNIP2 -5186.0
COPB1 -5206.0
EEF1A1 -5249.0
POLR3H -5258.0
MMP25 -5310.0
FGG -5317.0
SFTPA2 -5330.0
ATOX1 -5341.0
PRG3 -5370.0
UBE2D1 -5373.0
CHGA -5385.0
HMOX2 -5418.0
ATF1 -5430.0
CASP1 -5440.0
ABCA13 -5525.0
RBSN -5541.0
FYN -5611.0
AOC1 -5616.0
SERPINB10 -5642.0
HLA-E -5719.0
C8A -5738.0
ACP3 -5766.0
VAMP8 -5797.0
IKBKE -5842.0
PGLYRP1 -5867.0
PSMB8 -5916.0
BPIFA2 -5930.0
TMEM179B -5970.0
C3AR1 -5982.0
TARM1 -5994.0
PPP2R5D -6069.0
IQGAP1 -6084.0
RAB5B -6124.0
CDC34 -6129.0
DYNLT1 -6168.0
C6 -6193.0
UBE2D3 -6196.0
SLC2A3 -6239.0
CD53 -6258.0
CNPY3 -6262.0
RIPK2 -6272.0
PTPN6 -6309.0
MALT1 -6361.0
NFATC1 -6385.0
KRAS -6424.0
CD4 -6432.0
TMC6 -6433.0
PSMA7 -6451.0
PLAC8 -6464.0
CHRNB4 -6508.0
YPEL5 -6589.0
MUC5AC -6591.0
CYLD -6620.0
DEFB115 -6631.0
ISG15 -6637.0
EPPIN-WFDC6 -6685.0
ARL8A -6737.0
CGAS -6749.0
C8G -6791.0
GUSB -6805.0
PPP3CB -6841.0
CAND1 -6871.0
TOM1 -6875.0
VCP -6876.0
ELANE -6877.0
BST1 -6915.0
CD55 -6939.0
HBB -6946.0
MAPK3 -6971.0
LRG1 -6990.0
NFKB1 -6991.0
TANK -6996.0
DEGS1 -7042.0
IFIH1 -7050.0
PIGR -7147.0
PSMB4 -7154.0
GSDME -7158.0
TTR -7178.0
PSMB5 -7180.0
WASF1 -7185.0
ATAD3B -7222.0
TRIM4 -7248.0
UBE2V1 -7263.0
CTSB -7274.0
BCL2L1 -7322.0
PKP1 -7329.0
COLEC11 -7338.0
ITGAX -7369.0
CEACAM3 -7374.0
PGLYRP4 -7426.0
HLA-C -7433.0
RAB4B -7469.0
PGAM1 -7482.0
IMPDH2 -7503.0
IFI16 -7517.0
CD68 -7522.0
UBA3 -7525.0
BPI -7527.0
PPIE -7559.0
C4A -7613.5
C4B -7613.5
AIM2 -7638.0
CYBA -7670.0
CR2 -7713.0
DHX9 -7717.0
BPIFB1 -7729.0
PSMB10 -7764.0
CALML5 -7770.0
NCKAP1L -7790.0
HSPA1A -7818.0
DHX36 -7824.0
OLFM4 -7828.0
TSPAN14 -7865.0
LTF -7930.0
AGA -7944.0
FRK -7989.0
AAMP -7990.0
MAPK10 -8002.0
C9 -8005.0
RNASET2 -8068.0
MRE11 -8073.0
TXNIP -8125.0
TLR5 -8131.0
PTPN11 -8183.0
STING1 -8241.0
DEFB134 -8274.0
SELL -8285.0
PIK3CA -8295.0
ITGB2 -8305.0
DEFB110 -8306.0
F2 -8376.0
MYH2 -8418.0
PSMA2 -8439.0
FUCA2 -8501.0
RHOA -8510.0
RIPK1 -8540.0
TREM2 -8541.0
DSP -8577.0
CRCP -8584.0
FPR1 -8604.0
LAMTOR3 -8671.0
PSMC4 -8740.0
POLR3K -8746.0
PTGES2 -8787.0
RAB18 -8810.0
SIGLEC5 -8813.0
FCN2 -8861.0
MGAM -8911.0
DEFB114 -8975.0
S100A11 -8978.0
SERPINA3 -8994.0
CLEC4D -9009.0
HTN3 -9012.0
CD3G -9055.0
DEFB135 -9091.0
LILRB3 -9104.0
TBC1D10C -9125.0
KLRD1 -9133.0
DSG1 -9152.0
PRSS3 -9175.0
IFNA8 -9181.0
SLPI -9243.0
LBP -9272.0
HLA-B -9341.0
CRISP3 -9402.0
ORM1 -9430.0
S100A7A -9510.0
CCR6 -9523.0
REG3A -9558.0
IFNA21 -9568.0
C4BPB -9674.0
PECAM1 -9700.0
CFHR4 -9753.0
PGLYRP3 -9754.0
DEFA4 -9801.0
LAT -9915.0
ITK -9945.0
SERPINB3 -9958.0
IFNA7 -10006.0
GNLY -10007.0
SAA1 -10057.0
BST2 -10093.0
FGA -10100.0
FCN1 -10149.0
IFNA5 -10158.0
DCD -10175.0
CFHR2 -10231.0
MMP8 -10264.0


REACTOME_OPIOID_SIGNALLING

REACTOME_OPIOID_SIGNALLING
23
set REACTOME_OPIOID_SIGNALLING
setSize 89
pANOVA 0.000808
s.dist 0.205
p.adjustANOVA 0.102



Top enriched genes

Top 20 genes
GeneID Gene Rank
GNG3 11153
GRK2 10489
PRKACG 10488
PRKACB 10345
ADCY7 10188
POMC 10147
PPP1R1B 9969
PPP2R1B 9868
CAMK2G 9864
GNG5 9602
CAMKK1 9539
GNAQ 9172
GNG11 8726
GNB5 8701
GNB3 8607
PRKAR2A 8520
CALM1 8425
PPP1CA 8210
PRKCD 7994
PRKAR2B 7439

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GNG3 11153
GRK2 10489
PRKACG 10488
PRKACB 10345
ADCY7 10188
POMC 10147
PPP1R1B 9969
PPP2R1B 9868
CAMK2G 9864
GNG5 9602
CAMKK1 9539
GNAQ 9172
GNG11 8726
GNB5 8701
GNB3 8607
PRKAR2A 8520
CALM1 8425
PPP1CA 8210
PRKCD 7994
PRKAR2B 7439
ADCY4 7377
GNG2 7368
PPP3CC 7311
GNG8 7259
ADCY9 7248
ADCY6 6969
CREB1 6748
GNAI2 6742
PDE4A 6565
CAMKK2 6291
PPP3R1 5990
ITPR2 5971
PDE1B 5931
GNG12 5882
ITPR3 5878
PRKAR1A 5418
PPP3CA 5341
PRKCA 5314
ADCY3 5100
GNA11 5021
PLA2G4A 5000
KPNA2 4937
PDE1C 4445
GNG4 4334
GNGT2 3968
ITPR1 3907
PRKACA 3386
PRKAR1B 3155
PPP2CA 2966
GNA14 2842
CAMK2B 2746
PLCB1 2103
PDE4C 2009
PDE1A 1890
GNG7 1756
PPP2R1A 1350
GNB4 1037
PLCB2 964
GNB1 949
OPRM1 297
CAMK2D 0
PLCB4 -77
PLCB3 -239
PPP2CB -251
GNA15 -267
MAPK1 -543
NBEA -597
GNAT3 -818
GNB2 -1598
PDE4D -1623
CAMK4 -1911
GNAI3 -2001
PRKCG -2149
PDE4B -3082
GNAI1 -3259
ADCY1 -3806
ADCY8 -3925
ADCY5 -3957
GNAL -4178
AHCYL1 -4631
PPP2R5D -6069
PDYN -6426
PPP3CB -6841
GNG13 -6899
GNGT1 -7193
CDK5 -7448
GNG10 -7730
ADCY2 -7909
CAMK2A -8144


REACTOME_RAB_GEFS_EXCHANGE_GTP_FOR_GDP_ON_RABS

REACTOME_RAB_GEFS_EXCHANGE_GTP_FOR_GDP_ON_RABS
1265
set REACTOME_RAB_GEFS_EXCHANGE_GTP_FOR_GDP_ON_RABS
setSize 81
pANOVA 0.00091
s.dist 0.213
p.adjustANOVA 0.107



Top enriched genes

Top 20 genes
GeneID Gene Rank
RAB3IL1 10741
RINL 10650
RAB12 10181
CHML 9944
MON1A 9633
RIN3 9632
HPS1 9596
AKT3 9381
AKT2 9374
RAB8A 9319
RAB5C 9071
RIN2 8926
DENND2D 8536
RAB13 8422
RAB5A 8355
RAB39A 8177
RAB32 7812
RAB31 7723
RAB1A 7661
MADD 7373

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RAB3IL1 10741
RINL 10650
RAB12 10181
CHML 9944
MON1A 9633
RIN3 9632
HPS1 9596
AKT3 9381
AKT2 9374
RAB8A 9319
RAB5C 9071
RIN2 8926
DENND2D 8536
RAB13 8422
RAB5A 8355
RAB39A 8177
RAB32 7812
RAB31 7723
RAB1A 7661
MADD 7373
DENND1B 7365
TRAPPC10 7269
RAB35 6810
DENND5A 6624
HPS4 6622
RAB3GAP1 6060
DENND1A 5739
RAB38 5731
DENND4C 5610
MON1B 5482
DENND2B 5293
RAB7A 5275
DENND3 5223
TRAPPC2L 5129
AKT1 4980
RIN1 4606
SBF1 4526
ULK1 4016
ANKRD27 3860
YWHAE 3795
TRAPPC9 3479
TRAPPC8 3403
RABGEF1 3389
ALS2CL 3251
SBF2 3131
RAB3A 2636
TRAPPC1 2352
GAPVD1 2168
TRAPPC6B 2090
DENND5B 2064
TRAPPC4 1952
DENND1C 1598
TRAPPC6A 1543
DENND6A 1342
RIC1 1257
TRAPPC3 1228
RAB6A 772
DENND6B 696
TRAPPC12 -68
DENND4B -172
RAB10 -247
DENND2C -439
ALS2 -464
GDI2 -477
RAB8B -1873
RAB27A -2506
TRAPPC13 -2597
RAB27B -2802
TRAPPC5 -3125
TRAPPC11 -3336
RAB14 -3984
RAB6B -4213
RAB1B -4401
DENND4A -4460
RGP1 -4753
RAB21 -6054
RAB5B -6124
RAB3GAP2 -6281
RAB3IP -7037
DENND2A -7773
RAB18 -8810


REACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN

REACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN
1284
set REACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN
setSize 37
pANOVA 0.00105
s.dist 0.311
p.adjustANOVA 0.115



Top enriched genes

Top 20 genes
GeneID Gene Rank
RYBP 10772
CBX2 10074
CBX8 9447
PHC3 9317
YAF2 9282
SMARCC2 9222
CSNK2A1 8521
PBRM1 8438
ARID1B 8255
SMARCD1 8112
PHC2 7840
ARID1A 7384
HIPK2 7223
SMARCD2 7058
SMARCA2 6711
SMARCA4 6508
SCMH1 6100
PCGF5 4794
CBFB 4644
RNF2 4576

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RYBP 10772
CBX2 10074
CBX8 9447
PHC3 9317
YAF2 9282
SMARCC2 9222
CSNK2A1 8521
PBRM1 8438
ARID1B 8255
SMARCD1 8112
PHC2 7840
ARID1A 7384
HIPK2 7223
SMARCD2 7058
SMARCA2 6711
SMARCA4 6508
SCMH1 6100
PCGF5 4794
CBFB 4644
RNF2 4576
EP300 4318
CSNK2A2 4143
CBX4 3261
SMARCC1 2938
PHC1 2529
RUNX1 1665
BMI1 1028
ARID2 656
SMARCB1 624
ACTL6A -57
CSNK2B -224
AUTS2 -678
SMARCD3 -1011
SMARCE1 -1431
RING1 -5068
ACTL6B -6095
CBX6 -8018


REACTOME_MATURATION_OF_PROTEIN_3A

REACTOME_MATURATION_OF_PROTEIN_3A
1545
set REACTOME_MATURATION_OF_PROTEIN_3A
setSize 9
pANOVA 0.00114
s.dist 0.626
p.adjustANOVA 0.117



Top enriched genes

Top 20 genes
GeneID Gene Rank
GALNT1 10695
ST6GALNAC4 9383
ST6GAL1 8800
ST3GAL2 8289
ST3GAL4 7924
ST3GAL3 7811
ST6GALNAC2 6472
ST3GAL1 5428
ST6GALNAC3 3589

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GALNT1 10695
ST6GALNAC4 9383
ST6GAL1 8800
ST3GAL2 8289
ST3GAL4 7924
ST3GAL3 7811
ST6GALNAC2 6472
ST3GAL1 5428
ST6GALNAC3 3589


REACTOME_TOLL_LIKE_RECEPTOR_TLR1_TLR2_CASCADE

REACTOME_TOLL_LIKE_RECEPTOR_TLR1_TLR2_CASCADE
226
set REACTOME_TOLL_LIKE_RECEPTOR_TLR1_TLR2_CASCADE
setSize 109
pANOVA 0.00177
s.dist 0.173
p.adjustANOVA 0.171



Top enriched genes

Top 20 genes
GeneID Gene Rank
S100A8 11501
TLR4 11228
TLR1 11039
S100A9 10944
RELA 10539
SIGIRR 10330
TRAF6 10162
MAP2K1 10138
IRAK2 9952
AGER 9946
PPP2R1B 9868
DUSP3 9676
TAB1 9549
PELI2 9276
LRRC14 9234
FOS 9224
N4BP1 8982
PELI3 8873
TLR6 8756
RPS6KA1 8744

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
S100A8 11501
TLR4 11228
TLR1 11039
S100A9 10944
RELA 10539
SIGIRR 10330
TRAF6 10162
MAP2K1 10138
IRAK2 9952
AGER 9946
PPP2R1B 9868
DUSP3 9676
TAB1 9549
PELI2 9276
LRRC14 9234
FOS 9224
N4BP1 8982
PELI3 8873
TLR6 8756
RPS6KA1 8744
LY96 8736
MAP3K8 8624
IRAK3 8381
SFTPA1 8350
NFKBIA 8320
HMGB1 8140
MYD88 7926
ECSIT 7762
S100A1 7756
CUL1 7485
DUSP6 7423
MAP3K7 7351
S100B 7337
IKBKB 7170
UBC 6789
CREB1 6748
RPS6KA2 6218
MEF2A 6047
NLRX1 6001
MAPKAPK2 5929
NLRC5 5774
FGB 5732
CD14 5691
RPS6KA5 5668
NOD2 5535
SKP1 5453
APP 5402
ALPK1 5014
BTRC 4739
TIRAP 4274
MAPK9 4184
MAP2K6 4147
MAP2K3 4044
MAPK11 3652
CHUK 3407
NKIRAS1 3231
TP53 3222
MAPK8 3125
PPP2CA 2966
MAP2K7 2784
CD36 2158
TRAF2 2076
PPP2R1A 1350
VRK3 989
MEF2C 824
SFTPD 737
NOD1 506
MAP2K4 89
NFKBIB -11
PELI1 -80
PPP2CB -251
IKBIP -352
RPS27A -480
MAPK1 -543
USP14 -851
UBA52 -1027
MAPK7 -1333
SOCS1 -1940
FBXW11 -2091
S100A12 -2389
TAB2 -2478
UBB -2864
MAP3K1 -3071
NKIRAS2 -3355
IRAK4 -3377
MAPKAPK3 -3439
DUSP4 -3669
CASP8 -3681
TLR2 -3985
JUN -4010
UBE2N -4015
MAPK14 -4119
DUSP7 -4151
USP18 -4276
TIFA -4463
ATF2 -4821
NFKB2 -4827
TNIP2 -5186
FGG -5317
SFTPA2 -5330
ATF1 -5430
PPP2R5D -6069
RIPK2 -6272
MAPK3 -6971
NFKB1 -6991
UBE2V1 -7263
MAPK10 -8002
SAA1 -10057
FGA -10100


REACTOME_PLATELET_CALCIUM_HOMEOSTASIS

REACTOME_PLATELET_CALCIUM_HOMEOSTASIS
703
set REACTOME_PLATELET_CALCIUM_HOMEOSTASIS
setSize 27
pANOVA 0.00202
s.dist 0.343
p.adjustANOVA 0.174



Top enriched genes

Top 20 genes
GeneID Gene Rank
P2RX3 10586
P2RX6 10416
P2RX1 10251
ATP2B1 9852
SRI 9157
CALM1 8425
ATP2A3 8416
ORAI2 7911
P2RX5 7402
ITPR2 5971
ITPR3 5878
STIM1 5765
P2RX4 5675
P2RX2 5658
SLC8A2 5504
SLC8A3 4234
TRPC3 4011
ITPR1 3907
SLC8A1 3262
ORAI1 1805

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
P2RX3 10586
P2RX6 10416
P2RX1 10251
ATP2B1 9852
SRI 9157
CALM1 8425
ATP2A3 8416
ORAI2 7911
P2RX5 7402
ITPR2 5971
ITPR3 5878
STIM1 5765
P2RX4 5675
P2RX2 5658
SLC8A2 5504
SLC8A3 4234
TRPC3 4011
ITPR1 3907
SLC8A1 3262
ORAI1 1805
P2RX7 1754
ATP2A1 293
TRPC6 -66
ATP2B2 -946
ATP2A2 -1448
ATP2B4 -4819
TRPC7 -7826


REACTOME_SYNTHESIS_OF_IP2_IP_AND_INS_IN_THE_CYTOSOL

REACTOME_SYNTHESIS_OF_IP2_IP_AND_INS_IN_THE_CYTOSOL
291
set REACTOME_SYNTHESIS_OF_IP2_IP_AND_INS_IN_THE_CYTOSOL
setSize 13
pANOVA 0.00203
s.dist 0.494
p.adjustANOVA 0.174



Top enriched genes

Top 20 genes
GeneID Gene Rank
IMPA1 11421
MIOX 11004
INPP5J 10682
ISYNA1 10431
INPP4A 8307
INPP5B 7305
SYNJ1 7062
INPP4B 4872
INPP5A 4193
MTMR7 3367
INPP1 3343
MTMR9 1496
IMPA2 -3581

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
IMPA1 11421
MIOX 11004
INPP5J 10682
ISYNA1 10431
INPP4A 8307
INPP5B 7305
SYNJ1 7062
INPP4B 4872
INPP5A 4193
MTMR7 3367
INPP1 3343
MTMR9 1496
IMPA2 -3581


REACTOME_CA_DEPENDENT_EVENTS

REACTOME_CA_DEPENDENT_EVENTS
26
set REACTOME_CA_DEPENDENT_EVENTS
setSize 36
pANOVA 0.00218
s.dist 0.295
p.adjustANOVA 0.174



Top enriched genes

Top 20 genes
GeneID Gene Rank
GRK2 10489
PRKACG 10488
PRKACB 10345
ADCY7 10188
CAMK2G 9864
CAMKK1 9539
PRKAR2A 8520
CALM1 8425
PRKCD 7994
PRKAR2B 7439
ADCY4 7377
ADCY9 7248
ADCY6 6969
CREB1 6748
CAMKK2 6291
PDE1B 5931
PRKAR1A 5418
PRKCA 5314
ADCY3 5100
PLA2G4A 5000

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GRK2 10489
PRKACG 10488
PRKACB 10345
ADCY7 10188
CAMK2G 9864
CAMKK1 9539
PRKAR2A 8520
CALM1 8425
PRKCD 7994
PRKAR2B 7439
ADCY4 7377
ADCY9 7248
ADCY6 6969
CREB1 6748
CAMKK2 6291
PDE1B 5931
PRKAR1A 5418
PRKCA 5314
ADCY3 5100
PLA2G4A 5000
KPNA2 4937
PDE1C 4445
PRKACA 3386
PRKAR1B 3155
CAMK2B 2746
PDE1A 1890
CAMK2D 0
MAPK1 -543
NBEA -597
CAMK4 -1911
PRKCG -2149
ADCY1 -3806
ADCY8 -3925
ADCY5 -3957
ADCY2 -7909
CAMK2A -8144


REACTOME_DAG_AND_IP3_SIGNALING

REACTOME_DAG_AND_IP3_SIGNALING
137
set REACTOME_DAG_AND_IP3_SIGNALING
setSize 40
pANOVA 0.00226
s.dist 0.279
p.adjustANOVA 0.174



Top enriched genes

Top 20 genes
GeneID Gene Rank
GRK2 10489
PRKACG 10488
PRKACB 10345
ADCY7 10188
CAMK2G 9864
CAMKK1 9539
PRKAR2A 8520
CALM1 8425
PRKCD 7994
PRKAR2B 7439
ADCY4 7377
ADCY9 7248
ADCY6 6969
CREB1 6748
CAMKK2 6291
ITPR2 5971
PDE1B 5931
ITPR3 5878
PRKAR1A 5418
PRKCA 5314

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GRK2 10489
PRKACG 10488
PRKACB 10345
ADCY7 10188
CAMK2G 9864
CAMKK1 9539
PRKAR2A 8520
CALM1 8425
PRKCD 7994
PRKAR2B 7439
ADCY4 7377
ADCY9 7248
ADCY6 6969
CREB1 6748
CAMKK2 6291
ITPR2 5971
PDE1B 5931
ITPR3 5878
PRKAR1A 5418
PRKCA 5314
ADCY3 5100
KPNA2 4937
PDE1C 4445
ITPR1 3907
PRKCE 3633
PRKACA 3386
PRKAR1B 3155
CAMK2B 2746
PDE1A 1890
CAMK2D 0
NBEA -597
PLCG1 -1585
CAMK4 -1911
PRKCG -2149
ADCY1 -3806
ADCY8 -3925
ADCY5 -3957
AHCYL1 -4631
ADCY2 -7909
CAMK2A -8144


REACTOME_INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS

REACTOME_INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS
1355
set REACTOME_INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS
setSize 299
pANOVA 0.00244
s.dist 0.102
p.adjustANOVA 0.174



Top enriched genes

Top 20 genes
GeneID Gene Rank
AREG 11141
PSMA8 10830
GRK2 10489
PRKACG 10488
PRKACB 10345
RHOG 10240
TRIB3 10209
ADCY7 10188
HDAC2 10177
TRAF6 10162
CBX2 10074
MTA1 9880
FGF8 9870
PPP2R1B 9868
CAMK2G 9864
PSMD4 9855
AGO1 9835
FGF22 9768
CAMKK1 9539
SRC 9536

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
AREG 11141
PSMA8 10830
GRK2 10489
PRKACG 10488
PRKACB 10345
RHOG 10240
TRIB3 10209
ADCY7 10188
HDAC2 10177
TRAF6 10162
CBX2 10074
MTA1 9880
FGF8 9870
PPP2R1B 9868
CAMK2G 9864
PSMD4 9855
AGO1 9835
FGF22 9768
CAMKK1 9539
SRC 9536
CBX8 9447
PSMA6 9410
PSMD12 9401
AKT3 9381
AKT2 9374
PHC3 9317
PIK3R2 9304
PDPK1 9291
KIT 9109
PSMD3 8951
FGF23 8841
HGF 8798
PSMB7 8791
RAC2 8775
FOXO3 8665
CSNK2A1 8521
PRKAR2A 8520
IRS2 8486
PML 8443
CALM1 8425
FGF2 8395
LAMTOR4 8272
PSMD11 8203
FLT3 8148
GAB1 8130
CHD3 8080
FGFR4 8058
PRKCD 7994
MYD88 7926
PHC2 7840
MKRN1 7801
PIP5K1C 7782
PSMD1 7599
PRKAR2B 7439
ADCY4 7377
PSMC2 7343
TGFA 7260
ADCY9 7248
GAB2 7008
TNRC6B 7006
USP13 6993
ADCY6 6969
FOXO1 6946
TNRC6C 6911
UBC 6789
IL1RL1 6752
CREB1 6748
PPARG 6623
TSC2 6618
LAMTOR2 6616
MTA3 6578
ESR2 6491
PIK3AP1 6389
FGFR1 6382
CAMKK2 6291
EREG 6225
SCMH1 6100
PSMD6 6097
ITPR2 5971
PDE1B 5931
ITPR3 5878
AGO2 5863
PSME4 5861
SLC38A9 5801
PHLPP1 5707
ERBB2 5682
FGFR2 5621
RRAGD 5608
IRS1 5558
RICTOR 5524
PRKAR1A 5418
LAMTOR1 5344
PRKCA 5314
PIK3R1 5287
TNRC6A 5266
NR4A1 5235
MET 5187
STRN 5179
SNAI2 5169
MECOM 5108
ADCY3 5100
TNKS 5063
AKT1 4980
NEDD4 4957
KPNA2 4937
SNAI1 4880
PIK3CB 4871
RPS6KB2 4866
FGF18 4798
MLST8 4778
PIP4K2B 4666
AGO4 4656
RNF2 4576
PDE1C 4445
SALL4 4386
GRB2 4291
GATAD2A 4282
CSNK2A2 4143
PSMA1 4142
ERBB3 4105
GSK3B 3960
STUB1 3942
ITPR1 3907
PSMD8 3787
RHEB 3779
PSMD2 3775
PSMA4 3755
PPP2R5E 3735
PRKCE 3633
PDGFB 3630
IL33 3609
CHUK 3407
PRKACA 3386
TRIM27 3370
EZH2 3329
MAPKAP1 3299
WWP2 3276
CBX4 3261
TP53 3222
PRKAR1B 3155
PSME1 3146
PSMF1 3071
PPP2CA 2966
RPTOR 2922
ATN1 2794
CAMK2B 2746
RAC1 2646
PHC1 2529
KL 2517
FGF10 2490
IL1RAP 2426
PPP2R5C 2358
PSME3 2340
NRG2 2265
HDAC7 2254
PIP4K2C 2191
PDE1A 1890
SEM1 1800
VAV1 1771
PIP5K1A 1722
PDGFRA 1661
HDAC5 1544
PSMA3 1531
FRS2 1523
HBEGF 1513
PPP2R5A 1494
PIP5K1B 1408
PPP2R1A 1350
PRR5 1187
FGF7 1101
REST 1097
BMI1 1028
PSMD14 1026
CDKN1A 851
AGO3 705
AKT1S1 588
EPGN 509
OTUD3 501
PSMD13 355
IER3 284
RNF146 185
ESR1 94
FGF17 73
CD86 68
CAMK2D 0
FLT3LG -39
PSMA5 -94
PSMD7 -122
HDAC1 -138
CSNK2B -224
PPP2CB -251
PSMB2 -277
BAD -358
FGF9 -428
RPS27A -480
INSR -490
MTA2 -537
MAPK1 -543
PSMC5 -548
NBEA -597
GATAD2B -623
CASP9 -639
PREX2 -727
PIP4K2A -768
KLB -799
USP7 -900
RCOR1 -907
EGF -978
KITLG -1000
UBA52 -1027
PPP2R5B -1151
NRG1 -1153
MTOR -1162
ERBB4 -1505
NR2E1 -1510
EGFR -1566
PLCG1 -1585
PSMD9 -1799
SUZ12 -1847
CAMK4 -1911
PRKCG -2149
PSME2 -2193
MAF1 -2224
PIK3R3 -2329
PHLPP2 -2361
THEM4 -2409
PSMC6 -2500
FGF3 -2646
PTEN -2829
UBB -2864
FGFR3 -2884
FGF5 -2929
FGF1 -2957
LCK -3095
GSK3A -3140
PIK3CD -3346
LAMTOR5 -3351
PSMB6 -3363
IRAK4 -3377
PSMB3 -3408
MBD3 -3486
PSMB9 -3530
PSMB11 -3754
ADCY1 -3806
ADCY8 -3925
ADCY5 -3957
JUN -4010
PSMD5 -4134
NRG4 -4224
EED -4512
KDM1A -4587
MDM2 -4615
AHCYL1 -4631
ATF2 -4821
CD19 -4838
PSMC3 -4854
HDAC3 -4975
PSMC1 -5059
RING1 -5068
FGF19 -5085
PSMB1 -5095
PDGFRB -5228
FYN -5611
FGF4 -5822
PSMB8 -5916
PPP2R5D -6069
RRAGA -6238
PDGFA -6330
EGR1 -6402
PSMA7 -6451
MOV10 -6525
INS -6613
FGF20 -6917
MAPK3 -6971
PSMB4 -7154
PSMB5 -7180
RBBP4 -7565
PSMB10 -7764
CDKN1B -7766
NRG3 -7850
ADCY2 -7909
CHD4 -7943
FGF6 -7964
TNKS2 -7971
FRK -7989
CBX6 -8018
CAMK2A -8144
RRAGC -8156
PTPN11 -8183
PIK3CA -8295
PSMA2 -8439
LAMTOR3 -8671
PSMC4 -8740
CD80 -8848
TRAT1 -9237
BTC -9240
ICOS -9886
CD28 -9913
FOXO6 -9998


REACTOME_IRE1ALPHA_ACTIVATES_CHAPERONES

REACTOME_IRE1ALPHA_ACTIVATES_CHAPERONES
622
set REACTOME_IRE1ALPHA_ACTIVATES_CHAPERONES
setSize 48
pANOVA 0.00246
s.dist 0.253
p.adjustANOVA 0.174



Top enriched genes

Top 20 genes
GeneID Gene Rank
DDX11 11528
PREB 11041
PLA2G4B 10470
DNAJC3 10441
PDIA5 10324
ARFGAP1 10059
ADD1 9977
SYVN1 9087
LMNA 8958
CTDSP2 8608
HYOU1 8363
GFPT1 8054
EXTL3 8019
MYDGF 6638
CUL7 6071
YIF1A 5749
EDEM1 5693
DCTN1 5424
HSPA5 4717
TLN1 4535

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DDX11 11528
PREB 11041
PLA2G4B 10470
DNAJC3 10441
PDIA5 10324
ARFGAP1 10059
ADD1 9977
SYVN1 9087
LMNA 8958
CTDSP2 8608
HYOU1 8363
GFPT1 8054
EXTL3 8019
MYDGF 6638
CUL7 6071
YIF1A 5749
EDEM1 5693
DCTN1 5424
HSPA5 4717
TLN1 4535
GOSR2 4021
XBP1 3852
EXTL2 3776
ZBTB17 3737
ATP6V0D1 3420
SRPRA 3307
SRPRB 3220
EXTL1 3067
PDIA6 2970
ERN1 2838
KDELR3 2509
DNAJB9 2385
TPP1 1225
WFS1 -392
ACADVL -469
PPP2R5B -1151
HDGF -1229
CXXC1 -1289
WIPI1 -1290
SHC1 -1678
SSR1 -1920
DNAJB11 -1952
GSK3A -3140
SERP1 -3174
TATDN2 -3218
SEC31A -3764
KLHDC3 -4225
FKBP14 -7934


REACTOME_CELLULAR_RESPONSE_TO_STARVATION

REACTOME_CELLULAR_RESPONSE_TO_STARVATION
1582
set REACTOME_CELLULAR_RESPONSE_TO_STARVATION
setSize 147
pANOVA 0.00276
s.dist -0.143
p.adjustANOVA 0.174



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL7A -9849.0
RPL13A -9727.5
RPLP0 -9534.0
NPRL2 -9294.0
RPS3A -9277.0
RPL17 -9227.0
RPL3 -9097.0
RPL39L -8979.0
RPL29 -8969.0
RPL7 -8910.0
RPS18 -8789.0
ATF4 -8733.0
LAMTOR3 -8671.0
RPS2 -8633.0
RPSA -8411.0
RPL6 -8261.0
RPL34 -8230.0
RRAGC -8156.0
RPS13 -8088.0
RPL14 -8070.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL7A -9849.0
RPL13A -9727.5
RPLP0 -9534.0
NPRL2 -9294.0
RPS3A -9277.0
RPL17 -9227.0
RPL3 -9097.0
RPL39L -8979.0
RPL29 -8969.0
RPL7 -8910.0
RPS18 -8789.0
ATF4 -8733.0
LAMTOR3 -8671.0
RPS2 -8633.0
RPSA -8411.0
RPL6 -8261.0
RPL34 -8230.0
RRAGC -8156.0
RPS13 -8088.0
RPL14 -8070.0
RPS12 -7983.0
RPL23A -7919.0
RPL4 -7750.0
RPS20 -7733.0
RPS15A -7575.0
RPS15 -7544.0
ITFG2 -7481.0
DDIT3 -7451.0
CEBPG -7401.0
RPL30 -7313.0
RPL13 -7308.0
RPS6 -7197.0
RPL10A -7183.0
RPL5 -7176.0
RPS27 -7155.0
RPS23 -7108.0
SH3BP4 -6680.0
RRAGA -6238.0
EIF2S2 -5983.0
RPS11 -5654.0
RPL18A -5504.0
RPS8 -5492.0
RPL27A -5422.0
SEC13 -4988.0
RPL38 -4933.0
ATF2 -4821.0
GCN1 -4676.0
ATP6V1G2 -4540.0
ATP6V1G1 -4404.0
RPL21 -4309.0
ATP6V1D -3979.0
ATF3 -3921.0
RPL11 -3914.0
RPL37 -3378.0
LAMTOR5 -3351.0
RPL28 -3334.0
RPL22 -3268.0
EIF2S1 -3113.0
RPS10 -3097.0
RPL37A -2987.0
RPS28 -2923.0
RPS16 -2711.0
RPLP1 -2534.0
MIOS -2467.0
ATP6V1A -2433.0
ATP6V0E2 -2424.0
RPL36AL -2415.5
RPLP2 -2271.0
RPS3 -2211.0
RPL12 -2033.0
FNIP1 -1932.0
ATP6V1F -1916.0
RPS14 -1898.0
RPL41 -1768.0
RPL9 -1624.0
MTOR -1162.0
UBA52 -1027.0
ATP6V1B1 -492.0
RPS27A -480.0
WDR59 -206.0
SESN1 -173.0
RPS19 -100.0
KPTN 71.0
RPL35A 155.0
RPL27 186.0
ATP6V1C1 253.0
RPL31 415.0
RPL24 539.0
RPL22L1 834.0
DEPDC5 985.0
RPL18 1008.0
FLCN 1137.0
TCIRG1 2220.0
FAU 2277.0
RPS21 2323.0
ATP6V1C2 2362.0
ATP6V1H 2391.0
RPL23 2439.0
EIF2AK4 2676.0
RPS29 2769.0
ASNS 2773.0
NPRL3 2827.0
RPTOR 2922.0
RPL35 3004.0
ATP6V0D1 3420.0
RPS24 3487.0
RPS26 3565.0
RPL26L1 3578.0
RPL15 3621.0
RHEB 3779.0
RPS27L 3962.0
SEH1L 4151.0
WDR24 4492.0
RPS9 4613.0
MLST8 4778.0
ATP6V0B 5204.0
LAMTOR1 5344.0
ATP6V0C 5600.0
RPS5 5602.0
RRAGD 5608.0
ATP6V1B2 5664.0
RPS25 5728.0
SLC38A9 5801.0
BMT2 5837.0
RPL36 6037.0
RPL32 6039.0
RPL8 6252.0
IMPACT 6337.0
RPS7 6408.0
ATP6V0E1 6444.0
LAMTOR2 6616.0
RPL19 6666.0
ATP6V1G3 6755.0
SZT2 6899.0
KICS2 7267.0
ATP6V1E1 7510.0
RPL26 7892.0
CEBPB 7947.0
LAMTOR4 8272.0
SESN2 8397.0
ATP6V0D2 9714.0
ATP6V1E2 10030.0
TRIB3 10209.0
FNIP2 10527.0
CASTOR1 10809.0
RPL10L 11201.0
RPL3L 11448.0


REACTOME_SIGNALING_BY_ROBO_RECEPTORS

REACTOME_SIGNALING_BY_ROBO_RECEPTORS
605
set REACTOME_SIGNALING_BY_ROBO_RECEPTORS
setSize 206
pANOVA 0.00278
s.dist -0.121
p.adjustANOVA 0.174



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL7A -9849.0
RPL13A -9727.5
RPLP0 -9534.0
RPS3A -9277.0
RPL17 -9227.0
ETF1 -9115.0
RPL3 -9097.0
RPL39L -8979.0
MAGOH -8971.0
RPL29 -8969.0
RPL7 -8910.0
RPS18 -8789.0
PSMC4 -8740.0
RPS2 -8633.0
NELL2 -8528.0
RHOA -8510.0
PSMA2 -8439.0
RPSA -8411.0
PABPC1 -8320.0
RPL6 -8261.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL7A -9849.0
RPL13A -9727.5
RPLP0 -9534.0
RPS3A -9277.0
RPL17 -9227.0
ETF1 -9115.0
RPL3 -9097.0
RPL39L -8979.0
MAGOH -8971.0
RPL29 -8969.0
RPL7 -8910.0
RPS18 -8789.0
PSMC4 -8740.0
RPS2 -8633.0
NELL2 -8528.0
RHOA -8510.0
PSMA2 -8439.0
RPSA -8411.0
PABPC1 -8320.0
RPL6 -8261.0
RPL34 -8230.0
MSI1 -8137.0
RPS13 -8088.0
RPL14 -8070.0
ARHGAP39 -7993.0
RPS12 -7983.0
RPL23A -7919.0
PSMB10 -7764.0
RPL4 -7750.0
RPS20 -7733.0
RPS15A -7575.0
RPS15 -7544.0
ELOB -7497.0
RPL30 -7313.0
RPL13 -7308.0
RPS6 -7197.0
RPL10A -7183.0
PSMB5 -7180.0
RPL5 -7176.0
RPS27 -7155.0
PSMB4 -7154.0
RPS23 -7108.0
PPP3CB -6841.0
EIF4A3 -6771.0
NTN1 -6671.0
CAP2 -6652.0
PSMA7 -6451.0
ROBO2 -6176.0
USP33 -6170.0
CXCR4 -6006.0
GSPT1 -5954.0
PSMB8 -5916.0
SRGAP3 -5810.0
RPS11 -5654.0
MAGOHB -5595.0
RPL18A -5504.0
RPS8 -5492.0
RPL27A -5422.0
LHX4 -5214.0
PSMB1 -5095.0
PSMC1 -5059.0
ELOC -5058.0
ROBO1 -4949.0
RPL38 -4933.0
PSMC3 -4854.0
PFN1 -4816.0
RPL21 -4309.0
PSMD5 -4134.0
SLIT1 -4071.0
RPL11 -3914.0
LHX9 -3856.0
PSMB11 -3754.0
PAK5 -3572.0
RBM8A -3566.0
PSMB9 -3530.0
PSMB3 -3408.0
RPL37 -3378.0
PSMB6 -3363.0
RPL28 -3334.0
RPL22 -3268.0
NCK2 -3250.0
RPS10 -3097.0
RPL37A -2987.0
RPS28 -2923.0
ISL1 -2868.0
UBB -2864.0
RPS16 -2711.0
GPC1 -2599.0
RPLP1 -2534.0
PSMC6 -2500.0
RPL36AL -2415.5
RPLP2 -2271.0
RPS3 -2211.0
PSME2 -2193.0
PAK6 -2068.0
RPL12 -2033.0
LHX3 -1927.0
RPS14 -1898.0
PSMD9 -1799.0
RPL41 -1768.0
RPL9 -1624.0
DCC -1299.0
UBA52 -1027.0
AKAP5 -981.0
ABL2 -883.0
SOS1 -629.0
PSMC5 -548.0
RPS27A -480.0
PSMB2 -277.0
PSMD7 -122.0
SRGAP1 -114.0
RPS19 -100.0
PSMA5 -94.0
NCK1 75.0
RPL35A 155.0
RPL27 186.0
NCBP2 209.0
RNPS1 270.0
PSMD13 355.0
RPL31 415.0
RPL24 539.0
SLIT3 756.0
RPL22L1 834.0
LHX2 860.0
RPL18 1008.0
PSMD14 1026.0
CXCL12 1047.0
ROBO3 1316.0
PSMA3 1531.0
SEM1 1800.0
NCBP1 1937.0
HOXA2 1942.0
SLIT2 2027.0
CLASP1 2174.0
FAU 2277.0
RPS21 2323.0
PSME3 2340.0
RPL23 2439.0
CUL2 2477.0
RAC1 2646.0
RPS29 2769.0
RPL35 3004.0
UPF3A 3046.0
PSMF1 3071.0
PSME1 3146.0
CAP1 3180.0
PRKACA 3386.0
RPS24 3487.0
RPS26 3565.0
RPL26L1 3578.0
RPL15 3621.0
PSMA4 3755.0
PSMD2 3775.0
PSMD8 3787.0
RPS27L 3962.0
PSMA1 4142.0
LDB1 4486.0
RPS9 4613.0
RBX1 4824.0
ZSWIM8 4922.0
PAK1 5067.0
PRKCA 5314.0
RPS5 5602.0
RPS25 5728.0
ENAH 5800.0
FLRT3 5812.0
UPF2 5823.0
PSME4 5861.0
RPL36 6037.0
RPL32 6039.0
PSMD6 6097.0
RPL8 6252.0
RPS7 6408.0
DAG1 6524.0
RPL19 6666.0
CDC42 6736.0
MYO9B 6741.0
UBC 6789.0
ABL1 6822.0
PAK2 6918.0
PFN2 7022.0
EVL 7165.0
CLASP2 7262.0
PSMC2 7343.0
SOS2 7496.0
PSMD1 7599.0
RPL26 7892.0
NRP1 7927.0
SRGAP2 8045.0
PSMD11 8203.0
PRKAR2A 8520.0
PSMB7 8791.0
PSMD3 8951.0
CASC3 9037.0
PSMD12 9401.0
PSMA6 9410.0
SRC 9536.0
PSMD4 9855.0
EIF4G1 9917.0
VASP 9947.0
PAK4 10196.0
PRKACB 10345.0
PRKACG 10488.0
PSMA8 10830.0
RPL10L 11201.0
RPL3L 11448.0


REACTOME_HEMOSTASIS

REACTOME_HEMOSTASIS
3
set REACTOME_HEMOSTASIS
setSize 591
pANOVA 0.00278
s.dist 0.072
p.adjustANOVA 0.174



Top enriched genes

Top 20 genes
GeneID Gene Rank
PSG5 11585
SIRPA 11515
GP9 11502
SERPINB2 11429
HBG2 11386
PSG11 11384
GRB7 11377
PTGIR 11212
GNG3 11153
P2RY12 11117
TUBB1 11098
GYPA 11058
LY6G6F 10996
DGKZ 10966
JAML 10942
ADRA2C 10938
SLC7A7 10927
IFNA14 10848
FCER1G 10833
CLU 10819

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PSG5 11585.0
SIRPA 11515.0
GP9 11502.0
SERPINB2 11429.0
HBG2 11386.0
PSG11 11384.0
GRB7 11377.0
PTGIR 11212.0
GNG3 11153.0
P2RY12 11117.0
TUBB1 11098.0
GYPA 11058.0
LY6G6F 10996.0
DGKZ 10966.0
JAML 10942.0
ADRA2C 10938.0
SLC7A7 10927.0
IFNA14 10848.0
FCER1G 10833.0
CLU 10819.0
MAFK 10736.0
GP1BA 10680.0
P2RX3 10586.0
LEFTY2 10566.0
SLC16A8 10509.0
PRKACG 10488.0
CEACAM6 10474.0
ECM1 10462.0
P2RX6 10416.0
SOD1 10393.0
PSG2 10367.0
PRKACB 10345.0
ARRB1 10325.0
ACTN4 10316.0
P2RX1 10251.0
APLP2 10246.0
PSG7 10244.0
RHOG 10240.0
IFNA13 10215.0
HDAC2 10177.0
PPBP 10136.0
MAFG 10080.0
CEACAM8 10069.0
PIK3R6 9931.0
TREM1 9883.0
PPP2R1B 9868.0
ATP2B1 9852.0
CD177 9842.0
PSG1 9716.0
DGKE 9707.0
AHSG 9623.0
GNG5 9602.0
KIF3C 9566.0
SRC 9536.0
MMRN1 9534.0
PLAUR 9497.0
CLEC3B 9495.0
PTPN1 9429.0
SLC16A3 9380.0
TUBB6 9331.0
PIK3R2 9304.0
PDPK1 9291.0
CLEC1B 9270.0
LYN 9232.0
IFNA1 9218.0
GNAQ 9172.0
SERPINB6 9161.0
SRI 9157.0
GP1BB 9092.0
PLAT 9074.0
RASGRP2 9028.0
VTI1B 8993.0
PIK3R5 8988.0
MERTK 8967.0
AKAP1 8912.0
INPP5D 8839.0
TUBB2A 8817.0
HGF 8798.0
RAC2 8775.0
ITGA6 8728.0
GNG11 8726.0
GNB5 8701.0
AK3 8675.0
NRAS 8673.0
CALU 8617.0
MAFF 8616.0
GNB3 8607.0
H3C7 8600.5
MYB 8581.0
IRAG1 8573.0
PRKAR2A 8520.0
GNA13 8518.0
ACTN1 8517.0
GYPC 8504.0
CYB5R1 8483.0
NFE2 8470.0
ITPK1 8458.0
CALM1 8425.0
ATP2A3 8416.0
SLC7A5 8411.0
MPL 8398.0
TOR4A 8370.0
RAB5A 8355.0
DOCK2 8228.0
VCL 8223.0
RARRES2 8169.0
LRP8 8092.0
ATP1B1 8002.0
QSOX1 7995.0
PRKCD 7994.0
ORAI2 7911.0
DOCK9 7885.0
TUBAL3 7853.0
KIF2B 7841.0
PIK3CG 7804.0
F2RL2 7718.0
H3C1 7639.0
ANXA5 7497.0
KIF25 7474.0
PRKAR2B 7439.0
P2RX5 7402.0
ZFPM1 7392.0
GNG2 7368.0
PLEK 7361.0
TUBB4B 7350.0
PHF21A 7334.0
KCNMB1 7314.0
KIF21A 7265.0
GNG8 7259.0
SLC7A8 7244.0
CENPE 7236.0
CABLES1 7184.0
VPREB3 7160.0
CD9 7141.0
OLA1 7082.0
MAG 7057.0
TMX3 7025.0
ABHD12 7020.0
KIF1B 6992.0
DAGLB 6934.0
NOS3 6930.0
KLC1 6828.0
ABL1 6822.0
GNAI2 6742.0
CDC42 6736.0
KNG1 6722.0
MMP1 6607.0
H3-3B 6534.0
TUBA3E 6526.0
DGKG 6498.0
NHLRC2 6482.0
A1BG 6455.0
PSG9 6398.0
EHD3 6354.0
SRGN 6300.0
TGFB2 6234.0
SERPINA1 6130.0
S100A10 6107.0
ITGA2B 6096.0
F2RL3 6030.0
TUBA1A 6028.0
PLAU 5991.0
ITPR2 5971.0
PDE1B 5931.0
GNG12 5882.0
ITPR3 5878.0
CSK 5810.0
STIM1 5765.0
ABCC4 5754.0
EHD2 5737.0
FGB 5732.0
TUBA4A 5702.0
P2RX4 5675.0
F7 5662.0
P2RX2 5658.0
GUCY1B1 5583.0
ABHD6 5570.0
CD44 5565.0
SLC8A2 5504.0
PRKCH 5459.0
AKAP10 5426.0
PRKAR1A 5418.0
APP 5402.0
KIF2A 5375.0
PRKCA 5314.0
PIK3R1 5287.0
WDR1 5178.0
ANGPT4 5163.0
PHACTR2 5122.0
CD244 5071.0
PSAP 5060.0
KIF6 5053.0
F13A1 5049.0
GNA11 5021.0
PLA2G4A 5000.0
AKT1 4980.0
JMJD1C 4979.0
RAP1A 4971.0
GATA2 4938.0
CYRIB 4919.0
PIK3CB 4871.0
CD109 4811.0
ANGPT2 4795.0
JCHAIN 4793.0
F11R 4759.0
HSPA5 4717.0
PRKCB 4703.0
ITGAL 4696.0
IFNA16 4593.0
TLN1 4535.0
IRF2 4523.0
CARMIL1 4460.0
H3C4 4420.0
P2RY1 4413.0
CBX5 4393.0
KIF22 4369.0
GNG4 4334.0
KIF4B 4322.0
SDC4 4317.0
GRB2 4291.0
OLR1 4289.0
SELP 4280.0
CABLES2 4250.0
ITGA2 4249.0
CEACAM1 4237.0
SLC8A3 4234.0
ARRB2 4213.0
KIF13B 4191.0
ACTB 4173.0
PRKCQ 4146.0
H3C10 4139.0
SLC7A6 4128.0
ANXA2 4115.0
TNFRSF10D 4025.0
ITGA5 4019.0
TRPC3 4011.0
SDC3 3991.0
GNGT2 3968.0
ITPR1 3907.0
DOCK10 3883.0
THBD 3873.0
HRG 3859.0
MICAL1 3846.0
TUBA8 3828.0
ANGPT1 3797.0
PICK1 3740.0
PPP2R5E 3735.0
APOH 3730.0
GATA6 3713.0
GNA12 3706.0
PRKCE 3633.0
PDGFB 3630.0
ACTN2 3612.0
PDE11A 3601.0
KIF9 3552.0
TUBA1B 3509.0
THPO 3417.0
PRKACA 3386.0
F2R 3380.0
CDK2 3373.0
IFNA2 3369.0
ESAM 3327.0
KIF21B 3325.0
CD58 3286.0
SLC8A1 3262.0
MIF 3247.0
GATA4 3224.0
TP53 3222.0
CAP1 3180.0
JAM3 3176.0
PRKAR1B 3155.0
ZFPM2 3136.0
VAV3 3091.0
SERPINE2 3086.0
KIF1A 3033.0
YES1 3011.0
ORM2 2980.0
PPP2CA 2966.0
MGLL 2946.0
GNA14 2842.0
JAM2 2798.0
SERPING1 2719.0
H3C6 2674.0
RAC1 2646.0
IRF1 2495.0
FERMT3 2425.0
PPP2R5C 2358.0
A2M 2335.0
RAD51B 2304.0
BRPF3 2294.0
APOB 2258.0
IFNB1 2250.0
VEGFA 2176.0
CD36 2158.0
MFN2 2071.0
GTPBP2 2069.0
TUBB3 2065.0
FGR 1934.0
PDE1A 1890.0
KLC2 1876.0
CAPZA2 1873.0
STX4 1866.0
LHFPL2 1841.0
ORAI1 1805.0
VAV1 1771.0
GNG7 1756.0
P2RX7 1754.0
SCG3 1572.0
ITGB1 1520.0
PPP2R5A 1494.0
DOCK3 1485.0
VEGFB 1461.0
ALDOA 1448.0
RAP1B 1389.0
PPP2R1A 1350.0
VWF 1261.0
SLC16A1 1185.0
F12 1148.0
GATA5 1127.0
C1QBP 1055.0
GNB4 1037.0
CAPZA1 1005.0
GNB1 949.0
IGF1 941.0
BCAR1 909.0
PRTN3 900.0
HABP4 881.0
KIF1C 862.0
F5 843.0
SERPIND1 683.0
MFN1 679.0
NOS1 595.0
VPS45 526.0
DAGLA 520.0
ISLR 479.0
SERPINF2 394.0
H3-3A 393.0
KIFC1 323.0
PROS1 306.0
PRKCZ 304.0
ATP2A1 293.0
SH2B1 255.0
KIF12 238.0
EPCAM 169.0
JAK2 98.0
TFPI 77.0
PROCR 35.0
KIF5B 11.0
TTN -3.0
PDE2A -10.0
GLG1 -40.0
BSG -52.0
TRPC6 -66.0
KIF19 -72.0
HDAC1 -138.0
PF4 -140.0
SH2B3 -142.0
CDC37L1 -228.0
PPP2CB -251.0
GNA15 -267.0
SH2B2 -440.0
DGKD -449.0
MAPK1 -543.0
CFL1 -614.0
SOS1 -629.0
PRKG1 -728.0
PDE5A -765.0
GNAT3 -818.0
MANF -838.0
ENDOD1 -882.0
RCOR1 -907.0
ATP2B2 -946.0
CHID1 -968.0
EGF -978.0
NOS2 -1099.0
KIF20B -1122.0
PPP2R5B -1151.0
RAD51C -1220.0
PLCG2 -1234.0
TUBA4B -1324.0
PCYOX1L -1344.0
GRB14 -1387.0
PRKG2 -1390.0
ATP2A2 -1448.0
KIF3B -1460.0
CD84 -1471.0
PLCG1 -1585.0
GNB2 -1598.0
TNFRSF10B -1630.0
DOCK7 -1651.0
SCCPDH -1659.0
SHC1 -1678.0
DOCK4 -1682.0
KIF27 -1686.0
PLG -1831.0
GP5 -1849.0
F11 -1857.0
DGKB -1980.0
KIF23 -1992.0
GNAI3 -2001.0
DOCK8 -2042.0
KIF26A -2073.0
PRKCG -2149.0
ITGA3 -2162.0
PCDH7 -2189.0
STXBP3 -2251.0
ITGA1 -2277.0
CD63 -2307.0
PIK3R3 -2329.0
CAV1 -2331.0
KIF18B -2384.0
CFD -2403.0
CAPZB -2404.0
LCP2 -2589.0
GPC1 -2599.0
TEK -2672.0
CD47 -2673.0
COL1A1 -2709.0
LGALS3BP -2730.0
PROC -2749.0
TF -2763.0
STXBP2 -2779.0
FCAMR -2782.0
RAB27B -2802.0
KIF2C -2818.0
PAFAH2 -2827.0
KLC3 -2841.0
SERPINE1 -2860.0
F3 -2878.0
SERPINC1 -3072.0
LCK -3095.0
ATP1B2 -3201.0
GNAI1 -3259.0
KIF18A -3261.0
PTK2 -3278.0
H3C2 -3314.0
KIF26B -3343.0
ITGA4 -3349.0
RAPGEF4 -3427.0
VAV2 -3491.0
EHD1 -3506.0
SELENOP -3539.0
KIF11 -3549.0
ITGAV -3555.0
CXADR -3586.0
SDC1 -3594.0
DOK2 -3605.0
PRCP -3639.0
PPIA -3699.0
DOCK6 -3708.0
H3C8 -3755.0
TBXA2R -3814.0
SYK -3820.0
DOCK1 -3854.0
TEX264 -3936.0
DOCK5 -4007.0
SELE -4026.0
MAPK14 -4119.0
GUCY1A1 -4136.0
RAF1 -4187.0
APBB1IP -4202.0
SERPINA5 -4215.0
COL1A2 -4320.0
TUBB2B -4339.0
SLC7A11 -4461.0
ITIH3 -4488.0
RASGRP1 -4502.0
TGFB1 -4548.0
TUBB4A -4549.0
F10 -4556.0
KDM1A -4587.0
SLC3A2 -4619.0
FN1 -4634.0
RACGAP1 -4641.0
TNFRSF10A -4745.0
KIF15 -4782.0
ITGB3 -4784.0
HRAS -4793.0
PFN1 -4816.0
ATP2B4 -4819.0
CRK -4825.0
APOA1 -4864.0
DGKI -4891.0
DGKA -4893.0
MPIG6B -4926.0
CTSW -4999.0
VPREB1 -5013.0
IFNA6 -5028.0
VEGFC -5044.0
YWHAZ -5116.0
ITGAM -5118.0
DGKH -5119.0
TIMP3 -5187.0
FGG -5317.0
KLC4 -5332.0
THBS1 -5369.0
SPARC -5461.0
KCNMB3 -5472.0
SLC7A10 -5473.0
RBSN -5541.0
KIF5A -5598.0
FYN -5611.0
TAGLN2 -5614.0
IGF2 -5635.0
PPIL2 -5749.0
ATP1B3 -5882.0
PDE10A -5887.0
GATA3 -6023.0
PPP2R5D -6069.0
PF4V1 -6092.0
KIFAP3 -6112.0
HBD -6219.0
SDC2 -6280.0
PTPN6 -6309.0
PDGFA -6330.0
CEACAM5 -6411.0
KRAS -6424.0
CD48 -6644.0
SIN3A -6747.0
HBE1 -6762.0
KCNMA1 -6772.0
ADRA2A -6852.0
GNG13 -6899.0
KIF16B -6925.0
HBB -6946.0
MAPK3 -6971.0
RAPGEF3 -7016.0
KIF20A -7088.0
RHOB -7112.0
GNGT1 -7193.0
HMG20B -7233.0
WEE1 -7262.0
TUBA1C -7311.0
H3C3 -7330.0
ITGAX -7369.0
CEACAM3 -7374.0
CDK5 -7448.0
SIRPG -7475.0
KIFC2 -7484.0
IGLL1 -7490.0
H3C11 -7543.0
SERPINB8 -7553.0
GNG10 -7730.0
KIF3A -7742.0
TRPC7 -7826.0
FAM3C -7960.0
AAMP -7990.0
ALB -8003.0
PDE9A -8031.0
ITGA10 -8178.0
PTPN11 -8183.0
PSG4 -8191.0
SELL -8285.0
PIK3CA -8295.0
ITGB2 -8305.0
DGKQ -8347.0
TGFB3 -8353.0
F2 -8376.0
KCNMB2 -8441.0
GUCY1A2 -8445.0
RHOA -8510.0
SERPINA4 -8600.0
ITIH4 -8676.0
TUBA3C -8925.0
KCNMB4 -8931.0
SLC7A9 -8962.0
SERPINA3 -8994.0
GP6 -9015.0
PDPN -9071.0
GNAS -9118.0
ADRA2B -9153.0
SPN -9166.0
IFNA8 -9181.0
SELPLG -9186.0
KLKB1 -9322.0
H3C12 -9379.0
ORM1 -9430.0
CD2 -9493.0
IFNA21 -9568.0
CD74 -9618.0
PECAM1 -9700.0
SPP2 -9799.0
F13B -9885.0
LAT -9915.0
PSG8 -9960.0
IFNA7 -10006.0
TUBA3D -10043.0
HBG1 -10047.0
TUBB8 -10051.0
FGA -10100.0
IFNA5 -10158.0


REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY

REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY
1591
set REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY
setSize 33
pANOVA 0.00286
s.dist -0.3
p.adjustANOVA 0.174



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS3A -9277
RPS18 -8789
RPS2 -8633
RPSA -8411
RPS13 -8088
RPS12 -7983
RPS20 -7733
RPS15A -7575
RPS15 -7544
RPS6 -7197
RPS27 -7155
RPS23 -7108
RPS11 -5654
RPS8 -5492
EEF1A1 -5249
RPS10 -3097
RPS28 -2923
RPS16 -2711
RPS3 -2211
RPS14 -1898

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS3A -9277
RPS18 -8789
RPS2 -8633
RPSA -8411
RPS13 -8088
RPS12 -7983
RPS20 -7733
RPS15A -7575
RPS15 -7544
RPS6 -7197
RPS27 -7155
RPS23 -7108
RPS11 -5654
RPS8 -5492
EEF1A1 -5249
RPS10 -3097
RPS28 -2923
RPS16 -2711
RPS3 -2211
RPS14 -1898
HNRNPA1 -700
RPS27A -480
RPS19 -100
FAU 2277
RPS21 2323
RPS29 2769
RPS24 3487
RPS26 3565
RPS27L 3962
RPS9 4613
RPS5 5602
RPS25 5728
RPS7 6408


REACTOME_RAB_REGULATION_OF_TRAFFICKING

REACTOME_RAB_REGULATION_OF_TRAFFICKING
1359
set REACTOME_RAB_REGULATION_OF_TRAFFICKING
setSize 110
pANOVA 0.00316
s.dist 0.163
p.adjustANOVA 0.174



Top enriched genes

Top 20 genes
GeneID Gene Rank
TBC1D24 11279
RAB3IL1 10741
RINL 10650
RAB12 10181
CHML 9944
TBC1D2 9898
MON1A 9633
RIN3 9632
RABGAP1 9610
HPS1 9596
AKT3 9381
AKT2 9374
RAB8A 9319
RAB5C 9071
RIN2 8926
DENND2D 8536
RAB13 8422
RAB5A 8355
RAB39A 8177
RAB32 7812

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TBC1D24 11279
RAB3IL1 10741
RINL 10650
RAB12 10181
CHML 9944
TBC1D2 9898
MON1A 9633
RIN3 9632
RABGAP1 9610
HPS1 9596
AKT3 9381
AKT2 9374
RAB8A 9319
RAB5C 9071
RIN2 8926
DENND2D 8536
RAB13 8422
RAB5A 8355
RAB39A 8177
RAB32 7812
RAB31 7723
RAB1A 7661
TBC1D15 7569
MADD 7373
DENND1B 7365
GGA1 7323
TRAPPC10 7269
RAB35 6810
GGA2 6728
ARF6 6643
DENND5A 6624
HPS4 6622
TSC2 6618
RAB3GAP1 6060
TBC1D14 6059
DENND1A 5739
RAB38 5731
DENND4C 5610
MON1B 5482
DENND2B 5293
RAB7A 5275
DENND3 5223
TRAPPC2L 5129
AKT1 4980
TBC1D10A 4751
RIN1 4606
SBF1 4526
ULK1 4016
RAB11B 3950
ANKRD27 3860
YWHAE 3795
TBC1D16 3610
TRAPPC9 3479
TRAPPC8 3403
RABGEF1 3389
ALS2CL 3251
SBF2 3131
RAB3A 2636
TRAPPC1 2352
GAPVD1 2168
TRAPPC6B 2090
DENND5B 2064
TRAPPC4 1952
MAP1LC3B 1608
DENND1C 1598
TRAPPC6A 1543
DENND6A 1342
RIC1 1257
TRAPPC3 1228
RAB6A 772
DENND6B 696
TRAPPC12 -68
DENND4B -172
RAB10 -247
GGA3 -376
DENND2C -439
ALS2 -464
GDI2 -477
TSC1 -865
TBC1D20 -1106
RAB11A -1646
TBC1D17 -1732
GABARAP -1803
RAB8B -1873
RABEP1 -2143
RAB27A -2506
TRAPPC13 -2597
RAB27B -2802
RAB4A -3104
TRAPPC5 -3125
TRAPPC11 -3336
TBC1D13 -3435
GABARAPL2 -3804
RAB14 -3984
RAB33B -4059
RAB6B -4213
RAB1B -4401
DENND4A -4460
RGP1 -4753
TBC1D10B -4936
TBC1D7 -5135
RAB21 -6054
RAB5B -6124
RAB3GAP2 -6281
SYTL1 -6804
RAB3IP -7037
DENND2A -7773
OPTN -8051
RAB18 -8810
TBC1D10C -9125


REACTOME_LEISHMANIA_INFECTION

REACTOME_LEISHMANIA_INFECTION
1509
set REACTOME_LEISHMANIA_INFECTION
setSize 156
pANOVA 0.00317
s.dist 0.137
p.adjustANOVA 0.174



Top enriched genes

Top 20 genes
GeneID Gene Rank
DPEP2 11463
IL10 11218
GNG3 11153
PYCARD 10994
FCGR3A 10696
C3 10676
RELA 10539
WIPF3 10490
PRKACG 10488
PRKACB 10345
CTSG 10335
ADCY7 10188
ENTPD1 10097
IL1A 10064
GNG5 9602
SRC 9536
IL1B 9350
ADORA2B 9341
LYN 9232
FCGR2A 8938

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DPEP2 11463
IL10 11218
GNG3 11153
PYCARD 10994
FCGR3A 10696
C3 10676
RELA 10539
WIPF3 10490
PRKACG 10488
PRKACB 10345
CTSG 10335
ADCY7 10188
ENTPD1 10097
IL1A 10064
GNG5 9602
SRC 9536
IL1B 9350
ADORA2B 9341
LYN 9232
FCGR2A 8938
WIPF1 8882
RHBDF2 8852
NLRP3 8816
NCKIPSD 8807
GNG11 8726
GNB5 8701
MYO5A 8690
GNB3 8607
PRKAR2A 8520
CALM1 8425
DVL2 8362
BRK1 8230
FURIN 8075
ABI2 7617
PRKAR2B 7439
ADCY4 7377
GNG2 7368
ELMO1 7363
GNG8 7259
ADCY9 7248
IL18 7154
PSTPIP1 7073
ADCY6 6969
HMOX1 6881
NOXA1 6830
ABL1 6822
CREB1 6748
GNAI2 6742
MYO9B 6741
CDC42 6736
GGT1 6726
MEFV 5994
ITPR2 5971
GNG12 5882
ITPR3 5878
ACTR2 5785
P2RX4 5675
ACTR3 5420
PRKAR1A 5418
APP 5402
ADCY3 5100
GNG4 4334
GRB2 4291
CD163 4259
ACTB 4173
GNGT2 3968
ARPC4 3955
ITPR1 3907
MYO10 3546
HSP90AB1 3525
ACTG1 3513
PRKACA 3386
PRKAR1B 3155
MAPK8 3125
VAV3 3091
BAIAP2 3072
YES1 3011
WASL 2921
RAC1 2646
CYFIP2 2117
ARPC5 2012
CYSLTR2 1974
DVL3 1949
FGR 1934
NCKAP1 1920
NT5E 1868
IL6 1863
VAV1 1771
GNG7 1756
P2RX7 1754
ARPC2 1597
CYFIP1 1580
GNB4 1037
ABI1 994
GNB1 949
MYO1C 777
NCK1 75
PLK2 -381
WIPF2 -493
MAPK1 -543
MYH9 -803
GNAT3 -818
DVL1 -931
ARPC3 -1026
SUGT1 -1073
PLCG2 -1234
WASF3 -1271
PLCG1 -1585
GNB2 -1598
GNAI3 -2001
ENTPD5 -2034
TXN -2090
WASF2 -2166
ARPC1B -2248
ELMO2 -2273
GNAZ -3144
GGT5 -3155
WNT5A -3216
GNAI1 -3259
PTK2 -3278
NOXO1 -3381
VAV2 -3491
ARPC1A -3664
HCK -3712
ADCY1 -3806
SYK -3820
DOCK1 -3854
ADCY8 -3925
ADCY5 -3957
JUN -4010
MAPK14 -4119
CD247 -4301
ADAM17 -4351
GSDMD -4384
DPEP1 -4611
AHCYL1 -4631
CRK -4825
NFKB2 -4827
CASP1 -5440
FYN -5611
C3AR1 -5982
GNG13 -6899
MAPK3 -6971
NFKB1 -6991
DPEP3 -7005
WASF1 -7185
GNGT1 -7193
CYBA -7670
GNG10 -7730
NCKAP1L -7790
ADCY2 -7909
TXNIP -8125
FZD7 -8288
MYH2 -8418
CD3G -9055
GNAS -9118


REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS

REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS
789
set REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS
setSize 62
pANOVA 0.00318
s.dist 0.217
p.adjustANOVA 0.174



Top enriched genes

Top 20 genes
GeneID Gene Rank
SLC35C1 10533
FUOM 10453
ST3GAL6 9984
NPL 9803
CMAS 9723
ST6GALNAC4 9383
GNPNAT1 9268
ST6GAL1 8800
SLC35A1 8699
ST6GALNAC6 8558
ST3GAL2 8289
GFPT1 8054
ST3GAL4 7924
ST3GAL3 7811
NAGK 7476
AMDHD2 7224
DHDDS 6701
ST6GALNAC2 6472
ST3GAL5 6363
GMPPB 6057

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SLC35C1 10533
FUOM 10453
ST3GAL6 9984
NPL 9803
CMAS 9723
ST6GALNAC4 9383
GNPNAT1 9268
ST6GAL1 8800
SLC35A1 8699
ST6GALNAC6 8558
ST3GAL2 8289
GFPT1 8054
ST3GAL4 7924
ST3GAL3 7811
NAGK 7476
AMDHD2 7224
DHDDS 6701
ST6GALNAC2 6472
ST3GAL5 6363
GMPPB 6057
NEU3 5969
SRD5A3 5968
ST6GALNAC5 5825
ALG5 5700
SLC17A5 5633
ST3GAL1 5428
MVD 4901
NUS1 4770
PMM2 4615
FPGT 4524
UAP1 4452
GMDS 4275
ST6GALNAC3 3589
ST8SIA6 3530
NEU1 3330
NANS 3154
DPM2 3122
GFUS 2341
CTSA 1193
GFPT2 448
GLB1 413
DOLPP1 -132
ST8SIA1 -205
NEU2 -334
FCSK -338
ST6GAL2 -357
DPM3 -802
GMPPA -806
NUDT14 -1164
ST8SIA4 -1326
ST8SIA5 -1526
PGM3 -1860
ST8SIA3 -1867
NEU4 -3366
ST6GALNAC1 -3969
DOLK -4223
GNE -4265
PMM1 -4348
NANP -6275
MPI -6542
DPM1 -7256
ST8SIA2 -8384


REACTOME_METABOLISM_OF_LIPIDS

REACTOME_METABOLISM_OF_LIPIDS
880
set REACTOME_METABOLISM_OF_LIPIDS
setSize 709
pANOVA 0.00337
s.dist 0.0646
p.adjustANOVA 0.178



Top enriched genes

Top 20 genes
GeneID Gene Rank
DPEP2 11463
FABP3 11407
SLC51B 11299
SEC24B 11208
RXRA 11182
SLC51A 11162
ALOX5AP 11111
ACER2 11076
AGPAT2 10977
STARD6 10963
TECRL 10960
HSD17B7 10874
GPX2 10863
THEM5 10847
TPTE 10841
FABP7 10776
PPARGC1B 10734
FAR2 10711
INPP5J 10682
PTGDS 10627

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DPEP2 11463
FABP3 11407
SLC51B 11299
SEC24B 11208
RXRA 11182
SLC51A 11162
ALOX5AP 11111
ACER2 11076
AGPAT2 10977
STARD6 10963
TECRL 10960
HSD17B7 10874
GPX2 10863
THEM5 10847
TPTE 10841
FABP7 10776
PPARGC1B 10734
FAR2 10711
INPP5J 10682
PTGDS 10627
ACOT12 10608
SLC10A1 10587
PTGR2 10578
HPGDS 10508
PRKACG 10488
PLA2G4B 10470
DHCR24 10427
TSPOAP1 10389
GPAT2 10368
DGAT2 10358
PRKACB 10345
ACER1 10314
MBOAT1 10266
TRIB3 10209
MTMR10 10180
PLPP1 10154
POMC 10147
ALOX15 10022
B4GALNT1 9937
PIK3R6 9931
SLC27A3 9909
CDS1 9905
PLD4 9718
SQLE 9711
PIK3C2B 9691
AKR1C2 9679
MED8 9642
MED13L 9612
PLPP6 9598
GALC 9573
HSD17B13 9560
ACSL1 9544
SLC27A2 9483
PLA2G2A 9461
NCOR2 9454
ELOVL3 9443
PRKD3 9379
ACSL6 9345
GDPD5 9334
VAPB 9332
PIK3R2 9304
GDPD3 9299
FHL2 9285
SRD5A1 9266
SCAP 9241
CYP2J2 9187
TECR 9174
VDR 9129
PLBD1 9117
ESRRA 9104
LCLAT1 9103
FABP5 9079
SYNJ2 8996
PIK3R5 8988
AMACR 8962
GDPD1 8930
PLPP2 8922
LPCAT1 8914
AGPAT1 8906
ACACA 8904
NUDT19 8887
INPP5D 8839
SMPD2 8826
NDUFAB1 8824
PEMT 8808
ACACB 8779
ELOVL6 8776
LDLRAP1 8747
LTA4H 8737
NCOA6 8698
SPTSSB 8663
OXCT1 8619
GBA1 8591
STARD3 8527
CSNK2A1 8521
PPARA 8515
PLEKHA5 8495
MTF1 8489
RAB5A 8355
MED21 8337
INPP4A 8307
LIPI 8259
PPP1CA 8210
SLC44A1 8206
INPP5F 8204
DDHD1 8157
DGAT1 8141
HACD4 8118
CRAT 8079
CPT2 8077
PLD3 8067
ACBD4 8063
ABHD3 7996
LPIN1 7952
HSD17B4 7940
PLA2R1 7935
ACADS 7934
VAC14 7850
ARF1 7807
ALOX15B 7806
PIK3CG 7804
PNPLA2 7797
PIP5K1C 7782
CERS3 7781
IDI1 7776
PISD 7681
SLC44A4 7557
ACOT13 7521
CDS2 7507
ABCC1 7435
PLA1A 7426
DDHD2 7425
CYP2D6 7420
PLA2G1B 7354
NR1H2 7336
SP1 7297
FDPS 7296
LIPE 7276
RXRB 7234
HSD11B2 7230
INSIG2 7228
ACSL5 7209
HPGD 7175
TSPO 7103
SYNJ1 7062
STARD10 7061
RGL1 7002
CYP27A1 6999
PTGES3 6996
MMAA 6988
BDH1 6976
G0S2 6950
CDK19 6936
ARSG 6912
MED25 6907
ABCC3 6892
NRF1 6866
PTGS1 6836
MTMR3 6796
GGT1 6726
PLAAT2 6691
PCCB 6688
DHCR7 6656
HSD17B12 6650
PPARG 6623
KPNB1 6615
GPD1L 6608
LGMN 6587
MED24 6436
SUMF1 6336
CBR1 6284
SGPP2 6270
MED18 6202
HACD3 6167
GDE1 6160
NCOA2 6150
PLIN2 6142
OSBPL6 6094
ETNPPL 6079
AGPAT4 6046
ABCA1 5999
NEU3 5969
SRD5A3 5968
PLA2G15 5965
GSTM4 5943
MAPKAPK2 5929
MBOAT2 5927
PTDSS2 5924
PRXL2B 5921
AGPAT3 5910
CYP1B1 5891
OSBPL7 5766
CERS1 5723
PNPLA3 5635
STARD3NL 5628
CYP4B1 5607
GPD2 5606
MED23 5594
LPIN3 5514
ABCB4 5507
PI4KB 5460
CSNK1G2 5457
MCAT 5430
ACSM6 5398
ARNT 5389
SMPD3 5365
PLA2G6 5298
PIK3R1 5287
ALOX12 5283
CRLS1 5263
CHKB 5260
ACOT7 5252
MED10 5241
ACBD7 5240
MCEE 5220
THRAP3 5217
GPAT4 5161
ACSBG2 5152
ACAA1 5151
MED27 5107
TNFAIP8L1 5104
CLOCK 5086
STAR 5068
PSAP 5060
CHD9 5025
PLA2G4A 5000
MVD 4901
INPP4B 4872
PIK3CB 4871
PLD2 4870
PPT2 4861
AKR1C3 4847
MED13 4790
CYP2U1 4768
ALDH3B2 4761
GPS2 4744
ACAD10 4738
HMGCL 4730
GM2A 4715
ALDH3A2 4704
PIP4K2B 4666
NR1H3 4636
SLC44A2 4625
PIAS4 4609
GLIPR1 4601
FIG4 4552
SBF1 4526
OSBPL9 4505
FA2H 4434
ACADM 4418
OLAH 4363
MMUT 4344
EP300 4318
PGS1 4312
PON1 4286
FABP9 4232
KDSR 4205
GLB1L 4200
MTMR2 4166
LSS 4158
CSNK2A2 4143
CPT1A 4141
PTPMT1 4135
MED16 4126
PLA2G3 4076
TBL1XR1 4064
ACOT2 4047
MFSD2A 3998
NCOR1 3908
MED4 3861
VAPA 3811
PLAAT4 3792
ECHS1 3756
CYP7B1 3678
OSBPL1A 3667
PTDSS1 3663
HMGCR 3632
ALAS1 3620
FADS2 3618
CDIPT 3614
ACER3 3574
SCD 3537
ACOT8 3506
PLB1 3488
MTMR4 3475
MED6 3466
CYP39A1 3451
ARSB 3447
CHKA 3438
ESYT2 3430
MTMR6 3429
ESYT1 3419
FAM120B 3413
PRKACA 3386
HMGCLL1 3382
MTMR7 3367
NEU1 3330
PITPNM2 3303
PON2 3275
PHOSPHO1 3245
MBTPS1 3218
CREBBP 3198
UBE2I 3188
SPHK2 3148
SLC44A3 3133
SBF2 3131
CARM1 3061
CPNE3 3041
MED28 3029
ACOT11 3023
SPTSSA 2998
CERK 2969
SGPL1 2967
SEC24D 2960
SLC22A5 2955
MGLL 2946
CERS6 2887
ACAT1 2786
ACSL3 2775
OSBPL10 2738
AKR1B1 2672
PNPLA5 2608
FAAH 2593
SPTLC2 2570
MTMR14 2562
RUFY1 2559
ACOX3 2531
PON3 2513
CPT1B 2484
PCCA 2465
AKR1D1 2460
PPM1L 2408
FASN 2380
GPX1 2366
ELOVL5 2305
PHYH 2288
AHR 2214
PIP4K2C 2191
OSBPL3 2188
CD36 2158
AGPS 2131
NR1H4 2109
GBA2 2104
OSBPL5 2067
CGA 2062
NFYB 2049
LPCAT3 2008
ARSJ 1976
PRKD2 1972
PLA2G2F 1918
MVK 1915
DECR1 1823
SPNS2 1799
CYP4F8 1792
PITPNM1 1773
CHPT1 1767
TIAM2 1735
PIP5K1A 1722
MED26 1684
AKR1C4 1626
NFYC 1602
CUBN 1591
LTC4S 1558
CYP27B1 1508
ACOX2 1506
PPT1 1497
MTMR9 1496
PI4K2A 1470
FABP4 1468
PLD1 1425
PIP5K1B 1408
SCP2 1401
SMPD1 1379
NFYA 1372
ACSF3 1224
HADH 1209
SREBF1 1202
CTSA 1193
CYP24A1 1142
HMGCS1 1138
PTGES 1122
HSD3B7 1088
BMAL1 1056
CYP4A11 1031
CCNC 1009
MIGA1 976
ALDH3B1 923
PI4KA 886
SLC25A17 874
MOGAT2 804
SLCO1A2 794
ARSA 735
PLEKHA8 731
TXNRD1 670
CYP11B2 665
ABCB11 658
MLYCD 635
ACAD11 623
ACSBG1 593
PRKAG2 543
GK2 473
ACBD5 460
ACSM3 425
GRHL1 416
GLB1 413
MIGA2 347
ACOT4 338
SC5D 215
ACBD6 139
ACLY 115
FADS1 52
TGS1 44
PIK3C2A 39
PTPN13 -35
SGMS1 -93
NCOA1 -129
PPARD -137
PIK3C3 -141
ELOVL7 -148
PITPNM3 -165
BCHE -166
CSNK2B -224
STARD4 -258
HACD2 -259
ABHD4 -264
SCD5 -305
CYP7A1 -318
MED29 -327
CYP4F22 -330
NEU2 -334
B3GALNT1 -356
OSBPL8 -382
GLTP -383
TMEM86B -403
HSD3B2 -424
DECR2 -457
ACADVL -469
ACSF2 -519
HSD17B2 -521
HEXA -551
SLC27A5 -575
FDX2 -600
ENPP6 -608
CYP1A1 -704
MED17 -743
CEPT1 -749
PIP4K2A -768
CYP4F11 -789
DEGS2 -796
ARSI -807
ETNK1 -813
HACD1 -815
MTMR12 -902
SLC44A5 -941
FABP2 -954
PLA2G12A -955
ARSK -980
SMARCD3 -1011
PLEKHA6 -1024
ABHD5 -1076
MED11 -1185
PTGIS -1240
PLA2G2E -1308
HSD17B3 -1312
TNFRSF21 -1336
SEC23A -1371
PITPNB -1416
TNFAIP8 -1438
ORMDL3 -1465
GPCPD1 -1492
MORC2 -1509
SACM1L -1513
LRP2 -1541
GNPAT -1560
ELOVL1 -1608
GPX4 -1640
PLAAT3 -1647
SAMD8 -1683
TBXAS1 -1701
ACHE -1703
CH25H -1734
SGPP1 -1738
FDFT1 -1750
PLAAT5 -1783
CERS4 -1800
PNPLA6 -1833
HACL1 -1839
MOGAT3 -1877
CERS2 -1894
NCOA3 -1921
MED9 -1939
PECR -1966
CYP2E1 -1993
SIN3B -2026
PLA2G4C -2060
UGT1A9 -2078
PLAAT1 -2097
ARV1 -2105
SGMS2 -2117
ALOX5 -2212
CROT -2235
EPHX2 -2282
CPNE1 -2305
ACAT2 -2312
PIK3R3 -2329
CAV1 -2331
LIPH -2336
THEM4 -2409
LPCAT4 -2465
ACSS3 -2471
PLEKHA2 -2492
CPTP -2535
HELZ2 -2738
GPAM -2816
PTEN -2829
FDX1 -2840
MBOAT7 -2861
HEXB -2881
HSD17B1 -2905
MED1 -2931
PCYT1A -2940
DHRS7B -2954
SREBF2 -2979
FABP1 -3055
FABP6 -3084
OSBP -3093
RAB4A -3104
CPNE7 -3116
PMVK -3118
ME1 -3126
GGT5 -3155
AGK -3160
PLEKHA1 -3237
CYP19A1 -3263
PIK3R4 -3265
PIK3CD -3346
NEU4 -3366
ASAH1 -3431
PIK3C2G -3451
ECI2 -3502
PEX11A -3516
CYP21A2 -3519
PNPLA8 -3526
CYP4F2 -3600
MED30 -3635
CYP11A1 -3684
CIDEA -3702
RORA -3735
PLIN3 -3736
PCTP -3757
INPPL1 -3761
FAR1 -3834
PNPLA7 -3864
PLEKHA3 -3895
HADHB -3970
RAB14 -3984
SEC24C -3986
HSD17B11 -3987
PLIN1 -4158
FDXR -4162
OSBPL2 -4209
CYP2C19 -4219
AGPAT5 -4341
FITM2 -4410
AKR1C1 -4526
CDK8 -4535
THRSP -4574
DPEP1 -4611
CERT1 -4645
STARD5 -4678
AKR1B15 -4757
IDI2 -4776
MECR -4802
SLC27A1 -4837
ECI1 -4845
SAR1B -4846
APOA1 -4864
ORMDL2 -4876
PPP1CC -4877
PRKAB2 -4889
INPP5E -4900
NR1D1 -4914
CBR4 -4932
LPGAT1 -4943
HDAC3 -4975
GPD1 -4982
AACS -5024
DBI -5114
CHAT -5117
MED15 -5180
ACOT1 -5232
CYP2R1 -5250
SELENOI -5265
PPARGC1A -5267
SRD5A2 -5312
HILPDA -5322
SEC24A -5324
SLCO1B3 -5412
PLPP3 -5449
ALOX12B -5454
EHHADH -5459
HAO2 -5561
BAAT -5590
ANGPTL4 -5670
NPAS2 -5680
AGT -5729
LPCAT2 -5828
INPP5K -5835
ETNK2 -5869
SLC25A1 -5886
PLEKHA4 -5904
STARD7 -5971
SPHK1 -6007
BDH2 -6018
PRKAA2 -6055
ACADL -6226
CYP17A1 -6282
UGCG -6306
SUMF2 -6325
GGPS1 -6341
ACP6 -6395
SERPINA6 -6463
RAN -6480
SULT2A1 -6490
FITM1 -6540
PRKD1 -6550
PLA2G4F -6565
CYP46A1 -6647
GC -6713
SIN3A -6747
LBR -6766
ARNT2 -6767
LHB -6780
TNFAIP8L2 -6790
PTGR1 -6818
TM7SF2 -6873
ALPI -6890
PCYT2 -6922
HSD17B14 -6956
DPEP3 -7005
PTGS2 -7009
CYP8B1 -7010
NUDT7 -7023
ESYT3 -7041
DEGS1 -7042
INSIG1 -7057
SMPD4 -7078
AGMO -7245
CYP51A1 -7303
ORMDL1 -7367
PPP1CB -7439
PLD6 -7443
UGT8 -7486
ACOXL -7498
PLA2G4D -7524
CYP2C8 -7546
TNFAIP8L3 -7560
CERS5 -7563
ACAA2 -7568
ALOXE3 -7570
MED31 -7595
ACOX1 -7653
PIKFYVE -7709
HMGCS2 -7831
MSMO1 -7854
SLC10A2 -7911
MED7 -7929
SPTLC3 -7937
PLA2G4E -7968
ALB -8003
SUMO2 -8033
ANKRD1 -8062
ELOVL4 -8268
PIK3CA -8295
SLC25A20 -8331
ELOVL2 -8352
MED19 -8387
APOA5 -8405
PIP4P1 -8421
CIDEC -8429
TPTE2 -8432
CPNE6 -8456
HADHA -8544
CYP3A4 -8578
HSD11B1 -8581
PLA2G5 -8606
APOA2 -8623
FABP12 -8759
MED20 -8768
PTGES2 -8787
ARF3 -8862
HSD3B1 -8877
CYP4F3 -8907
CYP2C9 -8944
MOGAT1 -9027
SPTLC1 -9054
CYP1A2 -9077
LPIN2 -9290
PI4K2B -9351
HSD17B8 -9371
MED22 -9468
SLCO1B1 -9520
PLA2G2D -9553
ASAH2 -9617
ACOT6 -9808
CYP4A22 -9835
CYP11B1 -9858
ENPP7 -10036
PLA2G10 -10041


REACTOME_VEGFR2_MEDIATED_VASCULAR_PERMEABILITY

REACTOME_VEGFR2_MEDIATED_VASCULAR_PERMEABILITY
848
set REACTOME_VEGFR2_MEDIATED_VASCULAR_PERMEABILITY
setSize 26
pANOVA 0.00357
s.dist 0.33
p.adjustANOVA 0.18



Top enriched genes

Top 20 genes
GeneID Gene Rank
CDH5 11360
TRIB3 10209
AKT3 9381
CTNND1 9377
AKT2 9374
PDPK1 9291
CALM1 8425
NOS3 6930
PAK2 6918
CTNNA1 6254
RICTOR 5524
PAK1 5067
AKT1 4980
MLST8 4778
MAPKAP1 3299
VAV3 3091
HSP90AA1 2720
RAC1 2646
VAV1 1771
CTNNB1 1521

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CDH5 11360
TRIB3 10209
AKT3 9381
CTNND1 9377
AKT2 9374
PDPK1 9291
CALM1 8425
NOS3 6930
PAK2 6918
CTNNA1 6254
RICTOR 5524
PAK1 5067
AKT1 4980
MLST8 4778
MAPKAP1 3299
VAV3 3091
HSP90AA1 2720
RAC1 2646
VAV1 1771
CTNNB1 1521
PRR5 1187
MTOR -1162
JUP -1895
CAV1 -2331
THEM4 -2409
VAV2 -3491


REACTOME_METABOLISM_OF_CARBOHYDRATES

REACTOME_METABOLISM_OF_CARBOHYDRATES
1138
set REACTOME_METABOLISM_OF_CARBOHYDRATES
setSize 279
pANOVA 0.00362
s.dist 0.101
p.adjustANOVA 0.18



Top enriched genes

Top 20 genes
GeneID Gene Rank
HYAL2 11207
PHKG1 11133
B3GNT7 11060
RHCE 11010
FUT2 10861
SLC9A1 10859
B4GALT6 10624
PFKFB2 10570
NDST2 10522
PHKG2 10511
PRKACG 10488
FUT4 10455
SORD 10426
PRKACB 10345
AKR1A1 10293
B3GALT2 10241
ENO2 10214
FUT6 10130
ST3GAL6 9984
PPP2R1B 9868

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
HYAL2 11207
PHKG1 11133
B3GNT7 11060
RHCE 11010
FUT2 10861
SLC9A1 10859
B4GALT6 10624
PFKFB2 10570
NDST2 10522
PHKG2 10511
PRKACG 10488
FUT4 10455
SORD 10426
PRKACB 10345
AKR1A1 10293
B3GALT2 10241
ENO2 10214
FUT6 10130
ST3GAL6 9984
PPP2R1B 9868
GCKR 9865
CHST14 9837
GYS1 9597
B4GALT1 9547
GALK1 9442
FBP1 9386
NUP37 9290
HK2 9198
NDST1 9105
HS6ST1 9080
XYLT1 9062
HK1 9000
G6PC3 8936
GPI 8883
FUT7 8836
PRELP 8827
CHPF2 8790
CSGALNACT1 8778
RPIA 8741
XYLT2 8708
ABCC5 8680
PGD 8669
CHSY1 8603
ST6GALNAC6 8558
EXT2 8525
CALM1 8425
ENO1 8290
ST3GAL2 8289
B3GNT3 8246
GYG1 8098
NDST4 8061
ST3GAL4 7924
G6PC2 7922
PYGM 7878
HGSNAT 7860
ST3GAL3 7811
HYAL3 7770
HAS3 7588
EXT1 7530
UGP2 7148
AGRN 7144
GLCE 7134
ADPGK 7125
ALDOC 7091
RANBP2 6991
B3GAT3 6953
AGL 6891
PCK2 6857
UBC 6789
NCAN 6690
GPC2 6530
CHST9 6513
SLC35D2 6463
KHK 6439
GALE 6362
RPE 6341
B3GNT2 6177
ALDOB 5973
MDH2 5932
PFKFB3 5907
DERA 5888
UST 5696
SLC37A1 5680
PYGB 5674
CHST12 5663
CEMIP 5661
PAPSS1 5647
CD44 5565
ST3GAL1 5428
NUP62 5345
HMMR 5289
ENO3 5066
TALDO1 5029
NDST3 5007
B3GAT2 4936
GAPDHS 4818
GALNS 4708
CHPF 4582
SLC26A2 4569
B4GALT7 4440
PHKB 4410
CRYL1 4406
NHLRC1 4370
SDC4 4317
PKM 4258
CHSY3 4236
GLB1L 4200
NAGLU 4178
SEH1L 4151
FUT5 4107
SLC26A1 4078
PGM2 3993
SDC3 3991
CHST11 3809
DSE 3798
GNS 3788
SLC25A13 3783
HYAL1 3676
CHST2 3643
B3GALT6 3629
SLC2A1 3528
CHST6 3496
ARSB 3447
PRKACA 3386
CHST3 3160
PRPS1L1 2999
PPP2CA 2966
PGM1 2881
HS3ST1 2695
DCXR 2678
AKR1B1 2672
EPM2A 2656
TKFC 2622
PC 2453
CHST1 2433
B4GALT5 2393
NUP93 2330
PGAM2 2179
CHST15 2098
HK3 2002
PFKL 1983
HAS2 1759
HS3ST3A1 1724
SLC35B2 1708
GALT 1679
NUP188 1653
PYGL 1611
HS2ST1 1585
GLYCTK 1518
SLC25A12 1509
ALDOA 1448
FUT3 1359
PPP2R1A 1350
HS3ST2 1284
FUT11 1268
MAN2B2 1267
NUP98 1115
BPGM 969
SHPK 902
MAN2C1 852
CSGALNACT2 787
PFKM 782
XYLB 702
SLC37A4 682
SLC25A10 680
CHST13 638
GNPDA2 475
GLB1 413
PFKFB4 233
PGP 114
MANBA 45
MDH1 41
GBE1 12
OGN -227
PPP2CB -251
SGSH -295
FMOD -296
POM121 -315
GOT1 -319
PFKP -320
GOT2 -362
NUP214 -368
RPS27A -480
HEXA -551
B3GNT4 -596
NUP133 -607
CHP1 -610
CSPG5 -631
NUP210 -657
B4GALT2 -844
PGM2L1 -873
RBKS -896
HSPG2 -1015
UBA52 -1027
RHD -1048
B4GALT3 -1141
ACAN -1148
NUP43 -1199
FUT1 -1225
FUT10 -1313
ALDH1A1 -1386
TPI1 -1461
NUP205 -1548
NDC1 -1880
TKT -2275
RAE1 -2351
AAAS -2469
GPC1 -2599
GNPDA1 -2650
HPSE2 -2706
HS6ST3 -2720
HS3ST5 -2750
UBB -2864
HEXB -2881
PGLS -2898
PAPSS2 -2904
GCK -2994
NUP54 -3047
MAN2B1 -3371
SDC1 -3594
NUP88 -3614
IDUA -3653
HPSE -3696
BCAN -3827
HAS1 -3840
NUP160 -3961
GPC5 -4302
B4GALNT2 -4433
B3GAT1 -4483
VCAN -4543
GAA -4665
POM121C -4951
TPR -4960
GPC6 -4967
SEC13 -4988
OMD -5107
DCN -5178
B3GALT5 -5199
GYS2 -5240
NUP35 -5516
NUP42 -5576
SLC25A1 -5886
CSPG4 -5892
SLC25A11 -5923
PPP2R5D -6069
LUM -6200
SDC2 -6280
PPP1R3C -6367
HS3ST3B1 -6430
SLC37A2 -6486
NUP50 -6545
SLC35B3 -6678
GUSB -6805
STAB2 -6898
NUP107 -7034
B3GALT4 -7056
NUP58 -7085
LYVE1 -7210
PGAM1 -7482
NUP85 -7584
B4GALT4 -7603
NUP155 -7615
GAPDH -7765
DSEL -7973
HS3ST6 -8087
NUP153 -8270
G6PC1 -8300
PCK1 -8527
FUT9 -8711
HS3ST4 -8767
CHST5 -8896
PGK2 -8914
B3GALT1 -8919
PKLR -8946
RPEL1 -8976
LALBA -9469
FBP2 -9608
KERA -9751
B4GAT1 -9863


REACTOME_RAC2_GTPASE_CYCLE

REACTOME_RAC2_GTPASE_CYCLE
1373
set REACTOME_RAC2_GTPASE_CYCLE
setSize 81
pANOVA 0.00374
s.dist 0.186
p.adjustANOVA 0.181



Top enriched genes

Top 20 genes
GeneID Gene Rank
SWAP70 11071
EPHA2 10946
DSG2 10475
PAK4 10196
CDC42EP4 9895
VAPB 9332
PIK3R2 9304
ARHGAP1 9041
STBD1 8823
RAC2 8775
BCR 8735
GIT1 8577
BRK1 8230
DOCK2 8228
ARHGAP26 8170
ARHGAP21 7969
ABI2 7617
ARHGAP17 7552
NCF2 7254
PREX1 6981

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SWAP70 11071
EPHA2 10946
DSG2 10475
PAK4 10196
CDC42EP4 9895
VAPB 9332
PIK3R2 9304
ARHGAP1 9041
STBD1 8823
RAC2 8775
BCR 8735
GIT1 8577
BRK1 8230
DOCK2 8228
ARHGAP26 8170
ARHGAP21 7969
ABI2 7617
ARHGAP17 7552
NCF2 7254
PREX1 6981
PAK2 6918
CDC42 6736
MTX1 6657
PGRMC2 6604
DEPDC1B 6553
TAOK3 6356
MPP7 6178
BAIAP2L1 5759
LEMD3 5442
SLITRK5 5367
MCAM 5350
LAMTOR1 5344
PIK3R1 5287
RAB7A 5275
LMAN1 5239
NCF4 5213
ABR 5207
PAK1 5067
PLD2 4870
SAMM50 4804
DEF6 4688
TIAM1 4201
DIAPH3 4090
DOCK10 3883
ESYT1 3419
VAV3 3091
ANKLE2 2389
NCKAP1 1920
VAV1 1771
SYDE1 1600
CYFIP1 1580
ITGB1 1520
DOCK3 1485
ABI1 994
TRIO 972
VANGL1 206
GARRE1 -655
VRK2 -771
TFRC -1280
ERBIN -1676
DOCK4 -1682
WASF2 -2166
PIK3R3 -2329
CAV1 -2331
GIT2 -3264
ARHGAP35 -3383
VAV2 -3491
DOCK1 -3854
CDC42EP1 -3915
TMPO -4014
ARHGDIA -4455
RACGAP1 -4641
VAMP3 -4843
ARHGAP42 -5568
IQGAP1 -6084
LBR -6766
ARHGAP32 -7241
CYBA -7670
NCKAP1L -7790
ARHGAP39 -7993
PIK3CA -8295


REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING

REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING
675
set REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING
setSize 30
pANOVA 0.00386
s.dist 0.305
p.adjustANOVA 0.181



Top enriched genes

Top 20 genes
GeneID Gene Rank
GNG3 11153
PIK3R6 9931
GNG5 9602
AKT3 9381
AKT2 9374
PDPK1 9291
PIK3R5 8988
GNG11 8726
GNB5 8701
GNB3 8607
PIK3CG 7804
GNG2 7368
GNG8 7259
CDC42 6736
GNG12 5882
PAK1 5067
AKT1 4980
GNG4 4334
GNGT2 3968
PLCB1 2103

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GNG3 11153
PIK3R6 9931
GNG5 9602
AKT3 9381
AKT2 9374
PDPK1 9291
PIK3R5 8988
GNG11 8726
GNB5 8701
GNB3 8607
PIK3CG 7804
GNG2 7368
GNG8 7259
CDC42 6736
GNG12 5882
PAK1 5067
AKT1 4980
GNG4 4334
GNGT2 3968
PLCB1 2103
GNG7 1756
GNB4 1037
PLCB2 964
GNB1 949
PLCB3 -239
GNB2 -1598
GNG13 -6899
GNGT1 -7193
GNG10 -7730
RHOA -8510


REACTOME_G_PROTEIN_MEDIATED_EVENTS

REACTOME_G_PROTEIN_MEDIATED_EVENTS
27
set REACTOME_G_PROTEIN_MEDIATED_EVENTS
setSize 53
pANOVA 0.00434
s.dist 0.226
p.adjustANOVA 0.198



Top enriched genes

Top 20 genes
GeneID Gene Rank
GRK2 10489
PRKACG 10488
PRKACB 10345
ADCY7 10188
CAMK2G 9864
CAMKK1 9539
GNAQ 9172
PRKAR2A 8520
CALM1 8425
PRKCD 7994
PRKAR2B 7439
ADCY4 7377
ADCY9 7248
ADCY6 6969
CREB1 6748
GNAI2 6742
CAMKK2 6291
ITPR2 5971
PDE1B 5931
ITPR3 5878

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GRK2 10489
PRKACG 10488
PRKACB 10345
ADCY7 10188
CAMK2G 9864
CAMKK1 9539
GNAQ 9172
PRKAR2A 8520
CALM1 8425
PRKCD 7994
PRKAR2B 7439
ADCY4 7377
ADCY9 7248
ADCY6 6969
CREB1 6748
GNAI2 6742
CAMKK2 6291
ITPR2 5971
PDE1B 5931
ITPR3 5878
PRKAR1A 5418
PRKCA 5314
ADCY3 5100
GNA11 5021
PLA2G4A 5000
KPNA2 4937
PDE1C 4445
ITPR1 3907
PRKACA 3386
PRKAR1B 3155
GNA14 2842
CAMK2B 2746
PLCB1 2103
PDE1A 1890
PLCB2 964
CAMK2D 0
PLCB4 -77
PLCB3 -239
GNA15 -267
MAPK1 -543
NBEA -597
GNAT3 -818
CAMK4 -1911
GNAI3 -2001
PRKCG -2149
GNAI1 -3259
ADCY1 -3806
ADCY8 -3925
ADCY5 -3957
GNAL -4178
AHCYL1 -4631
ADCY2 -7909
CAMK2A -8144


REACTOME_CALNEXIN_CALRETICULIN_CYCLE

REACTOME_CALNEXIN_CALRETICULIN_CYCLE
1363
set REACTOME_CALNEXIN_CALRETICULIN_CYCLE
setSize 26
pANOVA 0.00456
s.dist 0.321
p.adjustANOVA 0.202



Top enriched genes

Top 20 genes
GeneID Gene Rank
CANX 11175
RNF103 10825
RNF139 9916
RNF5 9830
PDIA3 9635
MARCHF6 9624
SYVN1 9087
AMFR 8884
MAN1B1 8375
CALR 8004
TRIM13 7358
UBC 6789
RNF185 5827
EDEM1 5693
UGGT1 5684
EDEM2 5150
EDEM3 1844
UGGT2 -24
PRKCSH -309
RPS27A -480

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CANX 11175
RNF103 10825
RNF139 9916
RNF5 9830
PDIA3 9635
MARCHF6 9624
SYVN1 9087
AMFR 8884
MAN1B1 8375
CALR 8004
TRIM13 7358
UBC 6789
RNF185 5827
EDEM1 5693
UGGT1 5684
EDEM2 5150
EDEM3 1844
UGGT2 -24
PRKCSH -309
RPS27A -480
UBA52 -1027
OS9 -1596
SEL1L -2514
UBB -2864
GANAB -7181
DERL2 -7385


REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA

REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA
666
set REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA
setSize 25
pANOVA 0.00487
s.dist 0.325
p.adjustANOVA 0.21



Top enriched genes

Top 20 genes
GeneID Gene Rank
GNG3 11153
PIK3R6 9931
GNG5 9602
AKT3 9381
AKT2 9374
PDPK1 9291
PIK3R5 8988
GNG11 8726
GNB5 8701
GNB3 8607
PIK3CG 7804
GNG2 7368
GNG8 7259
GNG12 5882
AKT1 4980
GNG4 4334
GNGT2 3968
GNG7 1756
GNB4 1037
GNB1 949

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GNG3 11153
PIK3R6 9931
GNG5 9602
AKT3 9381
AKT2 9374
PDPK1 9291
PIK3R5 8988
GNG11 8726
GNB5 8701
GNB3 8607
PIK3CG 7804
GNG2 7368
GNG8 7259
GNG12 5882
AKT1 4980
GNG4 4334
GNGT2 3968
GNG7 1756
GNB4 1037
GNB1 949
GNB2 -1598
GNG13 -6899
GNGT1 -7193
GNG10 -7730
RHOA -8510


REACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS

REACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS
973
set REACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS
setSize 418
pANOVA 0.00524
s.dist 0.0796
p.adjustANOVA 0.214



Top enriched genes

Top 20 genes
GeneID Gene Rank
POLR2J 11645
AREG 11141
MAML1 10959
NEURL1B 10895
PSMA8 10830
DUSP8 10728
ETV6 10710
ARRB1 10325
NOTCH1 10270
RHOG 10240
APH1B 10203
HDAC2 10177
MAP2K1 10138
MYO18A 9885
FGF8 9870
PPP2R1B 9868
CAMK2G 9864
LRRFIP1 9863
PSMD4 9855
FGF22 9768

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
POLR2J 11645
AREG 11141
MAML1 10959
NEURL1B 10895
PSMA8 10830
DUSP8 10728
ETV6 10710
ARRB1 10325
NOTCH1 10270
RHOG 10240
APH1B 10203
HDAC2 10177
MAP2K1 10138
MYO18A 9885
FGF8 9870
PPP2R1B 9868
CAMK2G 9864
LRRFIP1 9863
PSMD4 9855
FGF22 9768
LRP6 9708
JAG1 9578
SRC 9536
NCOR2 9454
PSMA6 9410
PSMD12 9401
AKT3 9381
AKT2 9374
SMAD3 9367
PIK3R2 9304
PDPK1 9291
LYN 9232
KIT 9109
SYVN1 9087
TRIP11 9025
TRIM24 9014
LMNA 8958
PSMD3 8951
FGF23 8841
HGF 8798
PSMB7 8791
AGTRAP 8788
RAC2 8775
HEYL 8739
BCR 8735
NRAS 8673
FOXO3 8665
CARS1 8554
HIP1 8526
IRS2 8486
CALM1 8425
FGF2 8395
CNKSR1 8340
KANK1 8283
VCL 8223
TRAK1 8213
PSMD11 8203
FLT3 8148
GAB1 8130
TPM4 8117
BCL2A1 8106
FGFR4 8058
BCL2L11 7980
STAT1 7950
CEBPB 7947
KIAA1549 7908
PSMD1 7599
KAT2B 7558
CNTRL 7554
MAML2 7528
CUL1 7485
CUX1 7438
DUSP6 7423
POLR2B 7360
CPSF6 7348
PSMC2 7343
CBL 7300
BRAP 7277
TGFA 7260
FIP1L1 7162
MAP3K11 7150
DKK4 7034
GAB2 7008
RANBP2 6991
FOXO1 6946
MIB1 6929
CTBP1 6926
KLC1 6828
SQSTM1 6794
UBC 6789
PSEN2 6784
CREB1 6748
MIB2 6677
TSC2 6618
GTF2F2 6588
LRP5 6521
KSR1 6497
ESR2 6491
GCC2 6458
PIK3AP1 6389
FGFR1 6382
TCF7L2 6359
ADAM10 6349
MRAS 6313
HDAC4 6268
EREG 6225
PSMD6 6097
ITGA2B 6096
TPM3 6075
STAT5B 5936
RNF43 5919
PSME4 5861
DUSP16 5841
CSK 5810
FGB 5732
AXIN1 5698
ERBB2 5682
PAPSS1 5647
ATG7 5627
FGFR2 5621
IRS1 5558
STAT5A 5552
RICTOR 5524
FKBP1A 5473
MAML3 5464
SKP1 5453
DKK1 5433
DCTN1 5424
PRKAR1A 5418
CDC37 5383
PIK3R1 5287
CLCN6 5257
NR4A1 5235
MET 5187
STRN 5179
TNKS 5063
TGFBR1 5048
AKT1 4980
RAP1A 4971
CLTC 4928
POLR2D 4911
PIK3CB 4871
RPS6KB2 4866
RBX1 4824
FGF18 4798
MLST8 4778
MPRIP 4737
POLR2A 4709
HDAC10 4671
FAM131B 4639
TLN1 4535
LMO7 4387
EP300 4318
GRB2 4291
EML4 4278
ARRB2 4213
WDCP 4174
ACTB 4173
PSMA1 4142
ERBB3 4105
TBL1XR1 4064
NF1 3980
SPTBN1 3971
ESRP1 3970
GSK3B 3960
NCOR1 3908
KAT2A 3880
SMAD4 3870
PSMD8 3787
PSMD2 3775
PSMA4 3755
PPP2R5E 3735
DHH 3724
MAP2K2 3704
PDGFB 3630
HDAC11 3619
ACTG1 3513
FZD5 3435
MARK3 3410
CHUK 3407
MAPKAP1 3299
CREBBP 3198
PSME1 3146
PSMF1 3071
FZD8 3045
YES1 3011
PPP2CA 2966
AKAP9 2949
KDM7A 2917
BIRC6 2902
POLR2G 2901
AGGF1 2849
CAMK2B 2746
HSP90AA1 2720
PPFIBP1 2708
RAC1 2646
ZMYM2 2627
SND1 2579
KL 2517
FGF10 2490
QKI 2483
ERLEC1 2451
PPP2R5C 2358
PSME3 2340
NRG2 2265
HDAC7 2254
BCL11A 2184
TENT4A 2138
BIN2 2118
ZC3HC1 2112
STAT3 2046
NCBP1 1937
YWHAB 1889
PHB1 1851
SEM1 1800
VAV1 1771
PDGFRA 1661
PSENEN 1604
HDAC5 1544
PSMA3 1531
FRS2 1523
CTNNB1 1521
HBEGF 1513
PPP2R5A 1494
RAP1B 1389
PPP2R1A 1350
VWF 1261
PRR5 1187
NEURL1 1121
FGF7 1101
GTF2F1 1094
PSMD14 1026
CCNC 1009
TGFBR2 924
CDKN1A 851
DLL1 792
BRAF 712
BAG4 651
AKT1S1 588
HES1 551
EPGN 509
PSMD13 355
NCBP2 209
JAK2 98
ESR1 94
FGF17 73
CD86 68
KIF5B 11
CAMK2D 0
FLT3LG -39
ZC3HAV1 -45
PSMA5 -94
PSMD7 -122
HDAC1 -138
PPP2CB -251
PSMB2 -277
APC -325
RRBP1 -347
BAD -358
DLL4 -378
POLR2H -398
FGF9 -428
RPS27A -480
TFG -542
MAPK1 -543
PSMC5 -548
RBPJ -550
FAM114A2 -612
WNT3A -619
SOS1 -629
CASP9 -639
SHOC2 -716
KLB -799
MYH9 -803
JUNB -975
EGF -978
HEY2 -992
KITLG -1000
UBA52 -1027
POLR2F -1111
PPP2R5B -1151
NRG1 -1153
MTOR -1162
NPM1 -1230
ERBB4 -1505
WDR48 -1529
EGFR -1566
PLCG1 -1585
OS9 -1596
ERBIN -1676
SHC1 -1678
PSMD9 -1799
KREMEN1 -1805
POLR2C -1811
HDAC9 -1813
SPRED2 -1957
POLR2E -2107
PSME2 -2193
PIK3R3 -2329
PSMC6 -2500
SEL1L -2514
HEY1 -2559
FGF3 -2646
FXR1 -2735
FGFR1OP2 -2807
POLR2L -2825
PTEN -2829
UBB -2864
FGFR3 -2884
FBXW7 -2915
CSNK1A1 -2927
FGF5 -2929
FGF1 -2957
DUSP10 -2959
CEP43 -2975
LCK -3095
GSK3A -3140
AGK -3160
EEF1G -3234
PIK3CD -3346
PSMB6 -3363
PSMB3 -3408
PSMB9 -3530
NCSTN -3579
AP3B1 -3595
ZFYVE9 -3630
SMAD2 -3744
PSMB11 -3754
SEC31A -3764
PPM1B -3768
GOLGA4 -3892
HES5 -4061
RNF213 -4124
PSMD5 -4134
JAG2 -4142
DUSP7 -4151
RAF1 -4187
APBB1IP -4202
NRG4 -4224
ADAM17 -4351
PTPN12 -4358
EIF2AK3 -4380
CDK8 -4535
POLR2K -4538
TGFB1 -4548
MDM2 -4615
FN1 -4634
MYC -4661
SHH -4771
ITGB3 -4784
HRAS -4793
CD19 -4838
PSMC3 -4854
PPP1CC -4877
POLR2I -4956
TPR -4960
HDAC3 -4975
PSMC1 -5059
PSEN1 -5077
FGF19 -5085
PSMB1 -5095
PDGFRB -5228
KDR -5259
FGG -5317
PIM1 -5517
ALK -5543
ATIC -5583
FYN -5611
KREMEN2 -5706
HHAT -5707
FGF4 -5822
PSMB8 -5916
SNW1 -5960
FRS3 -6036
PPP2R5D -6069
IQGAP1 -6084
PDGFA -6330
KRAS -6424
PSMA7 -6451
ERLIN2 -6728
FZD6 -6764
VCP -6876
FGF20 -6917
MAPK3 -6971
IHH -7029
PSMB4 -7154
PSMB5 -7180
RPS6 -7197
CTBP2 -7282
BCL2L1 -7322
PEBP1 -7379
FZD4 -7381
DERL2 -7385
APH1A -7403
PPP1CB -7439
SPRED3 -7488
NOX4 -7759
PSMB10 -7764
CDKN1B -7766
NRG3 -7850
FGF6 -7964
TNKS2 -7971
CAMK2A -8144
PTPN11 -8183
SPRED1 -8227
PIK3CA -8295
DKK2 -8312
PSMA2 -8439
GOLGB1 -8443
KSR2 -8484
PSMC4 -8740
CD80 -8848
TRAT1 -9237
BTC -9240
ICOS -9886
CD28 -9913
FOXO6 -9998
FGA -10100


REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS
1438
set REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS
setSize 61
pANOVA 0.00527
s.dist 0.207
p.adjustANOVA 0.214



Top enriched genes

Top 20 genes
GeneID Gene Rank
B3GNT7 11060
GALNT1 10695
B4GALT6 10624
B3GNT9 10568
B3GNT8 10315
GALNT6 9430
ST6GALNAC4 9383
B3GNT5 9347
GCNT3 9248
GALNT4 9220
ST6GAL1 8800
MUC16 8322
ST3GAL2 8289
B3GNT3 8246
GALNT7 8155
ST3GAL4 7924
ST3GAL3 7811
A4GNT 7579
MUCL1 7342
MUC21 7324

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
B3GNT7 11060
GALNT1 10695
B4GALT6 10624
B3GNT9 10568
B3GNT8 10315
GALNT6 9430
ST6GALNAC4 9383
B3GNT5 9347
GCNT3 9248
GALNT4 9220
ST6GAL1 8800
MUC16 8322
ST3GAL2 8289
B3GNT3 8246
GALNT7 8155
ST3GAL4 7924
ST3GAL3 7811
A4GNT 7579
MUCL1 7342
MUC21 7324
C1GALT1 7147
GALNT10 7112
GALNT16 6531
GALNT11 6512
ST6GALNAC2 6472
GALNT2 6375
B3GNT2 6177
B3GNTL1 5893
GALNT12 5804
ST3GAL1 5428
MUC3A 4692
GCNT7 4679
MUC1 4381
ST6GALNAC3 3589
B4GALT5 2393
MUC17 2357
GALNTL6 2225
GALNT9 790
MUC5B 738
MUC6 47
MUC7 -298
B3GNT6 -369
MUC15 -524
B3GNT4 -596
GALNT14 -706
GALNT5 -2302
MUC12 -2623
MUC4 -2700
GALNT13 -3879
MUC13 -4117
GCNT1 -4160
GALNT15 -4851
MUC20 -4950
GALNT8 -5850
CHST4 -6450
GALNT3 -6521
MUC5AC -6591
GALNTL5 -6606
GCNT4 -7509
GALNT18 -7813
GALNT17 -7986


REACTOME_EXPORT_OF_VIRAL_RIBONUCLEOPROTEINS_FROM_NUCLEUS

REACTOME_EXPORT_OF_VIRAL_RIBONUCLEOPROTEINS_FROM_NUCLEUS
229
set REACTOME_EXPORT_OF_VIRAL_RIBONUCLEOPROTEINS_FROM_NUCLEUS
setSize 33
pANOVA 0.00533
s.dist -0.28
p.adjustANOVA 0.214



Top enriched genes

Top 20 genes
GeneID Gene Rank
NUP153 -8270
HSPA1A -7818
NUP155 -7615
NUP85 -7584
NUP58 -7085
NUP107 -7034
NUP50 -6545
RAN -6480
NUP42 -5576
NUP35 -5516
SEC13 -4988
TPR -4960
POM121C -4951
NUP160 -3961
NUP88 -3614
NUP54 -3047
XPO1 -2579
AAAS -2469
RAE1 -2351
NDC1 -1880

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NUP153 -8270
HSPA1A -7818
NUP155 -7615
NUP85 -7584
NUP58 -7085
NUP107 -7034
NUP50 -6545
RAN -6480
NUP42 -5576
NUP35 -5516
SEC13 -4988
TPR -4960
POM121C -4951
NUP160 -3961
NUP88 -3614
NUP54 -3047
XPO1 -2579
AAAS -2469
RAE1 -2351
NDC1 -1880
NUP205 -1548
NUP43 -1199
NUP210 -657
NUP133 -607
NUP214 -368
POM121 -315
NUP98 1115
NUP188 1653
NUP93 2330
SEH1L 4151
NUP62 5345
RANBP2 6991
NUP37 9290


REACTOME_MEMBRANE_TRAFFICKING

REACTOME_MEMBRANE_TRAFFICKING
374
set REACTOME_MEMBRANE_TRAFFICKING
setSize 603
pANOVA 0.00547
s.dist 0.0662
p.adjustANOVA 0.214



Top enriched genes

Top 20 genes
GeneID Gene Rank
TBC1D24 11279
CTSZ 11271
SEC24B 11208
AREG 11141
TOR1A 11122
TUBB1 11098
PREB 11041
AP1S1 10979
RAB3IL1 10741
GALNT1 10695
RINL 10650
CHMP6 10617
CLTB 10606
TXNDC5 10576
GRK2 10489
VPS37B 10463
DYNC1LI2 10429
ARRB1 10325
BLOC1S1 10280
RAB12 10181

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TBC1D24 11279
CTSZ 11271
SEC24B 11208
AREG 11141
TOR1A 11122
TUBB1 11098
PREB 11041
AP1S1 10979
RAB3IL1 10741
GALNT1 10695
RINL 10650
CHMP6 10617
CLTB 10606
TXNDC5 10576
GRK2 10489
VPS37B 10463
DYNC1LI2 10429
ARRB1 10325
BLOC1S1 10280
RAB12 10181
CPD 10115
EPS15L1 10091
ARFGAP1 10059
MAN1C1 9996
CHML 9944
TBC1D2 9898
GJA5 9783
STON1 9762
COG3 9689
GCC1 9668
TMED3 9657
MON1A 9633
RIN3 9632
AP1B1 9629
RABGAP1 9610
HPS1 9596
KIF3C 9566
MAN2A2 9554
SRC 9536
NAPA 9490
DCTN2 9425
AKT3 9381
AKT2 9374
ASPSCR1 9360
TUBB6 9331
RAB8A 9319
VPS4B 9229
GOLGA1 9176
VPS37C 9136
DNM2 9121
RAB5C 9071
TRIP11 9025
SYNJ2 8996
BICD1 8957
RIN2 8926
COPS6 8895
CYTH2 8878
TUBB2A 8817
TOR1B 8754
LDLRAP1 8747
CSNK1D 8695
MYO5A 8690
AP4E1 8656
AP1M2 8571
DENND2D 8536
HIP1 8526
AAK1 8490
PACSIN2 8464
VAMP2 8445
STX10 8431
CALM1 8425
PAFAH1B3 8423
RAB13 8422
SPTBN5 8419
DVL2 8362
RAB5A 8355
VTA1 8338
EXOC5 8260
RAB39A 8177
VPS53 8129
DYNLL2 8065
DYNC1H1 8043
HIP1R 8018
GJC1 7976
GJB6 7899
ANKRD28 7867
USP6NL 7857
TUBAL3 7853
KIF2B 7841
STON2 7833
RAB32 7812
ARF1 7807
PIP5K1C 7782
RAB31 7723
SLC2A8 7698
SPTA1 7694
RAB1A 7661
GJB2 7644
TBC1D1 7633
ACTR1A 7629
TBC1D15 7569
SCARB2 7523
KIF25 7474
PAFAH1B2 7472
CUX1 7438
CLINT1 7437
MADD 7373
DENND1B 7365
TSG101 7355
TUBB4B 7350
GGA1 7323
CNIH1 7310
CBL 7300
TRAPPC10 7269
KIF21A 7265
TGFA 7260
CENPE 7236
PPP6R3 7197
COL7A1 7181
DTNBP1 7176
ITSN2 7167
CYTH3 7114
SYNJ1 7062
VPS28 6994
KIF1B 6992
RALGAPA2 6952
GJD4 6848
KLC1 6828
RAB35 6810
GJD3 6808
UBC 6789
DNM3 6749
MAN2A1 6740
ZW10 6737
GGA2 6728
ARF6 6643
RALA 6626
DENND5A 6624
HPS4 6622
TSC2 6618
AP1S3 6595
RAB43 6592
TUBA3E 6526
DYNC1LI1 6503
GCC2 6458
GALNT2 6375
REPS1 6318
AP3S1 6257
AP2A1 6255
MVB12B 6247
AP2B1 6231
EREG 6225
TPD52 6154
SERPINA1 6130
RAB3GAP1 6060
TBC1D14 6059
RALGAPB 6056
TUBA1A 6028
SNX18 6010
PUM1 5918
AGPAT3 5910
SEC22C 5894
COPZ1 5814
SH3GL1 5807
ACTR2 5785
SPTAN1 5767
DENND1A 5739
RAB38 5731
SLC2A4 5719
TUBA4A 5702
DENND4C 5610
USO1 5561
MAN1A1 5523
NAPG 5509
MON1B 5482
DCTN1 5424
ACTR3 5420
APP 5402
KIF2A 5375
TMED10 5352
PLA2G6 5298
DENND2B 5293
UBAP1 5285
RAB7A 5275
VTI1A 5274
VPS54 5264
LMAN1 5239
SEC16A 5226
DENND3 5223
ADRB2 5206
STX6 5200
BET1L 5196
TRAPPC2L 5129
SNX9 5125
KIF6 5053
TACR1 5001
PLA2G4A 5000
CHMP4C 4986
AKT1 4980
CLTC 4928
GJB3 4843
CNIH2 4754
TBC1D10A 4751
EXOC7 4707
COPS8 4687
GJB4 4684
VPS37D 4670
RIN1 4606
COG7 4575
SORT1 4536
SBF1 4526
RHOQ 4525
FCHO1 4465
EPS15 4429
KIF22 4369
AP2A2 4330
KIF4B 4322
GRB2 4291
ARRB2 4213
GOSR1 4195
KIF13B 4191
ACTB 4173
LMAN2 4162
AVP 4037
GOSR2 4021
ULK1 4016
CHMP7 4012
SPTBN1 3971
ARPC4 3955
RAB11B 3950
ANKRD27 3860
TUBA8 3828
YWHAE 3795
GNS 3788
MIA3 3786
VAMP4 3718
COG5 3679
GORASP1 3657
TBC1D16 3610
KIF9 3552
TJP1 3524
ACTG1 3513
TUBA1B 3509
TRAPPC9 3479
GJA8 3426
TRAPPC8 3403
SPTB 3396
RABGEF1 3389
ARFGAP2 3376
LDLR 3362
SYS1 3338
KIF21B 3325
IGF2R 3310
CD59 3309
SEC22A 3295
ALS2CL 3251
PPP6R1 3237
ARF5 3183
SBF2 3131
BLOC1S6 3113
KIF1A 3033
ARFIP2 2982
MAN1A2 2968
SEC24D 2960
AP4S1 2954
WASL 2921
NAPB 2893
EXOC8 2797
EXOC4 2744
CHMP4A 2729
SYT11 2688
SNF8 2686
SNX2 2648
RAC1 2646
RAB3A 2636
GBF1 2588
STAM 2542
CTTN 2521
KDELR3 2509
KDELR1 2498
ALPP 2437
SNAPIN 2353
TRAPPC1 2352
APOB 2258
EXOC3 2228
GAPVD1 2168
TRAPPC6B 2090
TUBB3 2065
DENND5B 2064
STX5 2060
SYT8 2031
DYNC1I2 2026
ARPC5 2012
TRAPPC4 1952
NBAS 1940
VPS25 1931
VPS52 1929
GJB5 1905
YWHAB 1889
KLC2 1876
CAPZA2 1873
STX4 1866
RAB36 1838
C2CD5 1833
PAFAH1B1 1812
COPA 1794
DCTN5 1772
GOLIM4 1693
TMEM115 1614
MAP1LC3B 1608
DENND1C 1598
ARPC2 1597
AMPH 1589
TRAPPC6A 1543
FNBP1L 1537
CYTH4 1530
HBEGF 1513
VPS36 1464
STX17 1456
SYT2 1381
DENND6A 1342
CLVS2 1309
AP2M1 1287
RIC1 1257
BLOC1S4 1245
TRAPPC3 1228
SH3D19 1227
DYNLL1 1174
MYO6 1164
FTL 1149
SNAP29 1035
CAPZA1 1005
NECAP2 1004
KIF1C 862
HGS 859
PACSIN1 857
F5 843
RHOBTB3 807
DYNC1I1 803
BICD2 785
MYO1C 777
RAB6A 772
DENND6B 696
GJA10 584
FTH1 565
PRKAG2 543
VPS45 526
EPGN 509
SPTBN4 412
KIFC1 323
COPS3 295
GJA4 252
GAK 250
KIF12 238
DAB2 213
CHMP2B 124
PIK3C2A 39
KIF5B 11
TRAPPC12 -68
KIF19 -72
CLTA -73
COPG2 -128
GRK3 -130
CHRM2 -133
DENND4B -172
PICALM -230
RAB10 -247
SGIP1 -273
EXOC1 -365
GGA3 -376
KDELR2 -418
STX18 -419
DENND2C -439
ALS2 -464
GDI2 -477
RPS27A -480
STAM2 -509
TFG -542
CHMP2A -665
TBC1D4 -698
AGFG1 -712
MYH9 -803
GOLGA2 -834
NAA38 -847
TSC1 -865
SNAP91 -871
ACTR10 -878
NAA35 -919
EGF -978
ARPC3 -1026
UBA52 -1027
CHMP3 -1079
TBC1D20 -1106
KIF20B -1122
DNAJC6 -1168
EPN2 -1239
TFRC -1280
SCOC -1305
TUBA4B -1324
TMF1 -1368
SEC23A -1371
KIF3B -1460
ANK3 -1534
LRP2 -1541
EGFR -1566
COG4 -1579
MIA2 -1607
RAB11A -1646
KIF27 -1686
AP1M1 -1704
TBC1D17 -1732
GABARAP -1803
SNAP23 -1828
RAB8B -1873
DNM1 -1904
MCFD2 -1913
CNIH3 -1962
KIF23 -1992
NSF -2059
KIF26A -2073
TMED2 -2080
RABEP1 -2143
YWHAG -2203
STXBP3 -2251
DCTN4 -2324
SCFD1 -2354
M6PR -2360
COG6 -2381
KIF18B -2384
CAPZB -2404
YWHAQ -2431
EXOC2 -2445
RAB27A -2506
TMED7 -2521
TRIP10 -2522
TRAPPC13 -2597
AP1G2 -2647
TF -2763
RAB27B -2802
KIF2C -2818
KLC3 -2841
UBB -2864
GPS1 -2885
ITSN1 -2891
CLVS1 -2906
EXOC6 -2966
DNASE2 -2984
SURF4 -3058
RAB4A -3104
EPN1 -3111
DCTN6 -3115
TRAPPC5 -3125
WNT5A -3216
PRKAG1 -3241
SLC18A3 -3242
KIF18A -3261
LNPEP -3269
COPB2 -3333
TRAPPC11 -3336
KIF26B -3343
FNBP1 -3367
TBC1D13 -3435
KIF11 -3549
AP3B1 -3595
ARPC1A -3664
PACSIN3 -3700
BIN1 -3727
PLIN3 -3736
SEC31A -3764
GABARAPL2 -3804
COG2 -3832
GOLGA4 -3892
RAB14 -3984
SEC24C -3986
RAB33B -4059
ANK2 -4097
STX16 -4102
HSPA8 -4146
TPD52L1 -4206
RAB6B -4213
CTSC -4258
TUBB2B -4339
RAB1B -4401
ANK1 -4415
COPS2 -4416
DENND4A -4460
VPS4A -4506
COPS7B -4541
PRKAB1 -4544
TUBB4A -4549
RAB30 -4550
COPS7A -4558
USE1 -4637
RACGAP1 -4641
SNX5 -4660
GJC2 -4672
AP1G1 -4738
RGP1 -4753
KIF15 -4782
VAMP3 -4843
SAR1B -4846
PRKAB2 -4889
ARFGAP3 -4902
TBC1D10B -4936
SEC22B -4971
SEC13 -4988
YWHAZ -5116
TBC1D7 -5135
CHMP5 -5192
COPB1 -5206
SEC24A -5324
KLC4 -5332
VPS37A -5368
RABEPK -5392
CYTH1 -5431
BNIP1 -5474
ARL1 -5592
KIF5A -5598
TGOLN2 -5650
COPG1 -5660
AGTR1 -5664
CFTR -5673
BET1 -5775
VAMP8 -5797
SYT1 -5811
GJB7 -5825
SYT9 -5881
ARF4 -5977
RAB21 -6054
PRKAA2 -6055
GJA1 -6059
GOLGA5 -6074
KIFAP3 -6112
RAB5B -6124
YWHAH -6141
LMAN1L -6201
NEDD8 -6265
RAB3GAP2 -6281
COPZ2 -6307
CHMP4B -6352
YKT6 -6371
CD4 -6432
SH3GL2 -6520
UBQLN1 -6602
INS -6613
COG8 -6649
COG1 -6677
LMAN2L -6752
SYTL1 -6804
GJA9 -6811
KIF16B -6925
CD55 -6939
RAB3IP -7037
KIF20A -7088
PPP6C -7191
AP4B1 -7251
SPTBN2 -7264
SEC23IP -7266
TUBA1C -7311
COPS4 -7380
FZD4 -7381
BLOC1S3 -7479
KIFC2 -7484
FCHO2 -7532
GJD2 -7534
NAA30 -7581
COPE -7607
CLTCL1 -7619
KIF3A -7742
DENND2A -7773
COPS5 -7871
OPTN -8051
NECAP1 -8077
KIAA0319 -8185
AP4M1 -8257
GRIA1 -8301
GOLGB1 -8443
SH3GL3 -8486
MVB12A -8554
ARCN1 -8556
VPS51 -8585
GJA3 -8628
AP2S1 -8705
ACBD3 -8747
RAB18 -8810
ARF3 -8862
TUBA3C -8925
RINT1 -9037
CD3G -9055
TBC1D10C -9125
TMED9 -9156
BTC -9240
PRKAG3 -9270
FOLR1 -9299
DCTN3 -9329
ARFRP1 -9492
SEC16B -9550
IL7R -9611
TUBA3D -10043
TUBB8 -10051
CAPZA3 -10071
CD3D -10208
SFN -10224


REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX_WITHIN_TLR4_COMPLEX

REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX_WITHIN_TLR4_COMPLEX
1453
set REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX_WITHIN_TLR4_COMPLEX
setSize 15
pANOVA 0.00583
s.dist 0.411
p.adjustANOVA 0.223



Top enriched genes

Top 20 genes
GeneID Gene Rank
TLR4 11228
TICAM2 10754
TRAF6 10162
IRAK2 9952
TAB1 9549
LY96 8736
SARM1 7965
MAP3K7 7351
UBC 6789
CD14 5691
RPS27A -480
UBA52 -1027
TAB2 -2478
TICAM1 -2846
UBB -2864

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TLR4 11228
TICAM2 10754
TRAF6 10162
IRAK2 9952
TAB1 9549
LY96 8736
SARM1 7965
MAP3K7 7351
UBC 6789
CD14 5691
RPS27A -480
UBA52 -1027
TAB2 -2478
TICAM1 -2846
UBB -2864


REACTOME_SIGNALING_BY_CYTOSOLIC_FGFR1_FUSION_MUTANTS

REACTOME_SIGNALING_BY_CYTOSOLIC_FGFR1_FUSION_MUTANTS
286
set REACTOME_SIGNALING_BY_CYTOSOLIC_FGFR1_FUSION_MUTANTS
setSize 18
pANOVA 0.00626
s.dist 0.372
p.adjustANOVA 0.23



Top enriched genes

Top 20 genes
GeneID Gene Rank
MYO18A 9885
LRRFIP1 9863
TRIM24 9014
BCR 8735
STAT1 7950
CNTRL 7554
CUX1 7438
CPSF6 7348
GAB2 7008
STAT5B 5936
STAT5A 5552
PIK3R1 5287
GRB2 4291
ZMYM2 2627
STAT3 2046
FGFR1OP2 -2807
CEP43 -2975
PIK3CA -8295

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MYO18A 9885
LRRFIP1 9863
TRIM24 9014
BCR 8735
STAT1 7950
CNTRL 7554
CUX1 7438
CPSF6 7348
GAB2 7008
STAT5B 5936
STAT5A 5552
PIK3R1 5287
GRB2 4291
ZMYM2 2627
STAT3 2046
FGFR1OP2 -2807
CEP43 -2975
PIK3CA -8295


REACTOME_METABOLISM_OF_RNA

REACTOME_METABOLISM_OF_RNA
1313
set REACTOME_METABOLISM_OF_RNA
setSize 675
pANOVA 0.00643
s.dist -0.0615
p.adjustANOVA 0.23



Top enriched genes

Top 20 genes
GeneID Gene Rank
PWP2 -9877.0
RPL7A -9849.0
RPL13A -9727.5
RPLP0 -9534.0
SF3B6 -9490.0
ZFP36 -9375.0
RPS3A -9277.0
RPL17 -9227.0
EIF4A2 -9131.0
ETF1 -9115.0
SF3A2 -9110.0
RPL3 -9097.0
APOBEC3H -9016.0
TPRKB -8982.0
RPL39L -8979.0
MAGOH -8971.0
RPL29 -8969.0
TSEN34 -8954.0
RPL7 -8910.0
APOBEC3C -8891.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PWP2 -9877.0
RPL7A -9849.0
RPL13A -9727.5
RPLP0 -9534.0
SF3B6 -9490.0
ZFP36 -9375.0
RPS3A -9277.0
RPL17 -9227.0
EIF4A2 -9131.0
ETF1 -9115.0
SF3A2 -9110.0
RPL3 -9097.0
APOBEC3H -9016.0
TPRKB -8982.0
RPL39L -8979.0
MAGOH -8971.0
RPL29 -8969.0
TSEN34 -8954.0
RPL7 -8910.0
APOBEC3C -8891.0
PPWD1 -8804.0
TRMT1 -8791.0
RPS18 -8789.0
TYW5 -8772.0
PSMC4 -8740.0
CDK7 -8673.0
RPS2 -8633.0
TRIT1 -8617.0
WDR75 -8497.0
PSMA2 -8439.0
RPSA -8411.0
LSM7 -8371.0
PABPC1 -8320.0
NUP153 -8270.0
RPL6 -8261.0
RPL34 -8230.0
LTV1 -8221.0
RPP30 -8218.0
MFAP1 -8196.0
IMP3 -8154.0
EMG1 -8117.0
RPS13 -8088.0
RPL14 -8070.0
RPS12 -7983.0
RPL23A -7919.0
ZFP36L1 -7903.0
ZNF473 -7825.0
HSPA1A -7818.0
PSMB10 -7764.0
NOP56 -7755.0
RPL4 -7750.0
RPS20 -7733.0
QTRT1 -7727.0
DHX9 -7717.0
PCF11 -7703.0
HNRNPF -7682.0
SET -7635.0
NUP155 -7615.0
NUP85 -7584.0
RPS15A -7575.0
PPIE -7559.0
LSM11 -7545.0
RPS15 -7544.0
SRSF7 -7504.0
PHF5A -7389.0
EFTUD2 -7359.0
DIMT1 -7352.0
RPL30 -7313.0
RPL13 -7308.0
TRMT9B -7290.0
RRP9 -7230.0
RPS6 -7197.0
RPL10A -7183.0
PSMB5 -7180.0
RPL5 -7176.0
MRM1 -7168.0
SENP3 -7159.0
RPS27 -7155.0
PSMB4 -7154.0
RPS23 -7108.0
NUP58 -7085.0
NUP107 -7034.0
THOC7 -7024.0
IK -7003.0
ZBTB8OS -6963.0
PHAX -6901.0
PPP1R8 -6823.0
TSR3 -6821.0
FAM32A -6774.0
EIF4A3 -6771.0
SRRM2 -6751.0
SLU7 -6729.0
TRMT10C -6676.0
C2orf49 -6583.0
NUP50 -6545.0
CNOT9 -6530.0
SF3B4 -6487.0
RAN -6480.0
ISY1 -6456.0
PSMA7 -6451.0
DDX20 -6447.0
EDC3 -6446.0
XAB2 -6436.0
SF3B5 -6353.0
CSTF1 -6241.0
HNRNPL -6234.0
PNO1 -6228.0
SRSF11 -6213.0
QTRT2 -6197.0
SNIP1 -6061.0
DDX49 -6021.0
PRCC -5965.0
SNW1 -5960.0
GSPT1 -5954.0
SNRNP25 -5952.0
WDR36 -5947.0
TXNL4A -5940.0
PSMB8 -5916.0
CSTF3 -5893.0
SNRPF -5851.0
LSM4 -5796.0
RTRAF -5778.0
PRPF18 -5759.0
PPIL2 -5749.0
SRRM1 -5687.0
SRSF6 -5674.0
CNOT6 -5665.0
RPS11 -5654.0
MAGOHB -5595.0
SLBP -5579.0
NUP42 -5576.0
BUD23 -5557.0
ISG20L2 -5552.0
NUP35 -5516.0
RPL18A -5504.0
RPS8 -5492.0
SRSF5 -5456.0
WDR70 -5427.0
RPL27A -5422.0
RNPC3 -5357.0
UTP18 -5291.0
NIP7 -5279.0
TRMT13 -5159.0
WDR77 -5142.0
GEMIN2 -5128.0
YWHAZ -5116.0
PSMB1 -5095.0
MPHOSPH6 -5060.0
PSMC1 -5059.0
BCAS2 -5055.0
SEC13 -4988.0
CDC40 -4974.0
NSUN4 -4961.0
TPR -4960.0
POLR2I -4956.0
POM121C -4951.0
MRM3 -4940.0
POP7 -4938.0
RPL38 -4933.0
SNRPD3 -4931.0
THG1L -4923.0
PSMC3 -4854.0
CPSF7 -4835.0
U2SURP -4798.0
ZNF830 -4796.0
CACTIN -4777.0
ADAT1 -4743.0
UTP14C -4725.0
WDR4 -4711.0
UTP4 -4670.0
PRPF40A -4651.0
EXOSC5 -4639.0
FTSJ3 -4632.0
PNN -4607.0
SMG8 -4599.0
POLR2K -4538.0
PRORP -4480.0
GEMIN6 -4449.0
RBM39 -4427.0
SRSF3 -4418.0
SF3A3 -4342.0
SNRPA -4316.0
RPL21 -4309.0
SMG1 -4243.0
HNRNPC -4207.0
PDCD7 -4164.0
SRSF1 -4157.0
HSPA8 -4146.0
DHX37 -4143.0
PSMD5 -4134.0
MAPK14 -4119.0
TUT7 -4105.0
CNOT10 -4094.0
PRPF3 -4056.0
LSM8 -3966.0
NUP160 -3961.0
DDX46 -3924.0
RPL11 -3914.0
IGF2BP1 -3855.0
PUS7 -3838.0
UBL5 -3780.0
NSRP1 -3779.0
PPIH -3756.0
PSMB11 -3754.0
RTCB -3743.0
SYF2 -3674.0
NUP88 -3614.0
RBM8A -3566.0
PCBP1 -3543.0
PSMB9 -3530.0
PSMB3 -3408.0
RPL37 -3378.0
PSMB6 -3363.0
TRNT1 -3341.0
RPL28 -3334.0
PPIL3 -3329.0
SNRPB -3323.0
DCP1B -3304.0
DIS3 -3290.0
EIF4A1 -3282.0
RPL22 -3268.0
TRMT11 -3262.0
DDX21 -3240.0
ALYREF -3223.0
RPS10 -3097.0
YBX1 -3090.0
NUP54 -3047.0
TYW3 -3036.0
PAIP1 -3032.0
TRMU -3027.0
RPL37A -2987.0
U2AF1L4 -2943.0
RPS28 -2923.0
NSUN6 -2909.0
WTAP -2877.0
UBB -2864.0
PRPF19 -2848.0
PNRC2 -2838.0
POLR2L -2825.0
HNRNPK -2799.0
SMG5 -2744.0
RPS16 -2711.0
TSEN54 -2697.0
TRMT61B -2685.0
MTERF4 -2682.0
SART1 -2631.0
GCFC2 -2607.0
XPO1 -2579.0
ERCC2 -2566.0
RPLP1 -2534.0
PSMC6 -2500.0
POP4 -2494.0
PAN2 -2482.0
AAAS -2469.0
WBP11 -2460.0
RPL36AL -2415.5
TRMT6 -2414.0
HNRNPA2B1 -2366.0
SMN1 -2363.5
SMN2 -2363.5
RAE1 -2351.0
RPLP2 -2271.0
RPS3 -2211.0
CWC22 -2199.0
DHX38 -2197.0
PSME2 -2193.0
LSM3 -2145.0
POLR2E -2107.0
FAM98B -2054.0
METTL3 -2049.0
RPL12 -2033.0
NOP2 -2032.0
TSR1 -2017.0
SMU1 -1928.0
DDX42 -1924.0
DCP1A -1907.0
RPS14 -1898.0
NDC1 -1880.0
DDX23 -1866.0
POP5 -1851.0
POLR2C -1811.0
PSMD9 -1799.0
ZMAT2 -1797.0
RPL41 -1768.0
IMP4 -1760.0
SRSF10 -1692.0
SNRNP70 -1633.0
PCBP2 -1632.0
PTBP1 -1629.0
RPL9 -1624.0
NUP205 -1548.0
CPSF3 -1504.0
RNGTT -1409.0
SNRNP200 -1285.0
RBM25 -1278.0
LSM2 -1260.0
NUP43 -1199.0
RBM42 -1179.0
HNRNPH1 -1145.0
PUF60 -1129.0
WDR3 -1128.0
POLR2F -1111.0
RIOK1 -1039.0
SF3A1 -1030.0
UBA52 -1027.0
RPP38 -1007.0
TEX10 -999.0
EXOSC9 -984.0
DHX35 -972.0
MTREX -939.0
UTP15 -924.0
HNRNPU -858.0
CTU2 -849.0
ELAC2 -782.0
RPP21 -775.0
NOP58 -772.0
HNRNPA1 -700.0
NUP210 -657.0
CLNS1A -625.0
NUP133 -607.0
A1CF -601.0
WDR18 -576.0
CPSF4 -555.0
PSMC5 -548.0
DCAF13 -547.0
PAPOLA -487.0
RPS27A -480.0
FBL -470.0
CNOT3 -446.0
POLR2H -398.0
SNRPG -374.0
NUP214 -368.0
POM121 -315.0
CNOT7 -285.0
PSMB2 -277.0
PUS3 -270.0
BYSL -237.0
PUS1 -199.0
PSMD7 -122.0
TRMT112 -120.0
NOP10 -103.0
RPS19 -100.0
PSMA5 -94.0
WBP4 -75.0
EBNA1BP2 -58.0
XRN1 -54.0
METTL14 -44.0
HSPB1 -42.0
CTU1 -20.0
YJU2 -9.0
PAN3 15.0
NOL11 43.0
TGS1 44.0
CHTOP 53.0
LUC7L3 140.0
RPL35A 155.0
FCF1 166.0
RPL27 186.0
NCBP2 209.0
EXOSC1 216.0
POP1 231.0
EXOSC4 259.0
RNPS1 270.0
NSUN2 287.0
CCDC12 298.0
U2AF2 300.0
PSMD13 355.0
SARNP 376.0
RPL31 415.0
GEMIN7 428.0
RPP14 445.0
HNRNPR 455.0
SKIC3 470.0
LSM6 481.0
RPL24 539.0
HNRNPA3 546.0
SRSF4 732.0
UTP6 786.0
EXOSC8 802.0
SMG9 829.0
RPL22L1 834.0
KHSRP 861.0
XPOT 899.0
MTO1 928.0
UTP3 963.0
RPL18 1008.0
OSGEP 1014.0
PSMD14 1026.0
CWC27 1038.0
SNUPN 1049.0
GTF2F1 1094.0
NUP98 1115.0
CNOT2 1117.0
ADAT2 1120.0
NAT10 1152.0
CWF19L2 1201.0
RIOK2 1259.0
CDKAL1 1298.0
PPP2R1A 1350.0
PATL1 1365.0
BUD31 1369.0
TSEN15 1393.0
EIF4E 1409.0
LSM5 1460.0
TSEN2 1473.0
PRPF38A 1479.0
PSMA3 1531.0
RRP1 1571.0
DCPS 1645.0
NUP188 1653.0
SNRPN 1752.0
SRSF9 1786.0
SEM1 1800.0
SUGP1 1813.0
SF3B2 1831.0
UTP25 1879.0
YWHAB 1889.0
RCL1 1908.0
SYMPK 1912.0
CHERP 1913.0
NCBP1 1937.0
SNRPD2 1959.0
HNRNPD 2020.0
LCMT2 2024.0
PLRG1 2081.0
AQR 2089.0
PRPF8 2125.0
PRMT5 2177.0
NT5C3B 2199.0
ERCC3 2221.0
THOC3 2248.0
FAU 2277.0
SRSF2 2321.0
RPS21 2323.0
NOL6 2329.0
NUP93 2330.0
PSME3 2340.0
C1D 2378.0
RPL23 2439.0
ELAVL1 2445.0
TNPO1 2564.0
GPATCH1 2592.0
SMNDC1 2605.0
TBL3 2630.0
DDX5 2635.0
C9orf78 2714.0
CWC15 2750.0
RPS29 2769.0
SDE2 2862.0
POLR2G 2901.0
DDX1 2951.0
PPP2CA 2966.0
ALKBH8 2974.0
LENG1 2978.0
RPL35 3004.0
EXOSC7 3005.0
RBM28 3035.0
UPF3A 3046.0
PSMF1 3071.0
BUD13 3075.0
GAR1 3119.0
CPSF1 3132.0
PSME1 3146.0
PRKRIP1 3182.0
RNMT 3234.0
NOC4L 3301.0
FYTTD1 3375.0
RPPH1 3402.0
POLDIP3 3445.0
KRR1 3476.0
RPS24 3487.0
RIOK3 3512.0
NOL9 3550.0
RPS26 3565.0
RPL26L1 3578.0
RPL15 3621.0
DDX39A 3642.0
MAPK11 3652.0
CNOT8 3715.0
SF1 3753.0
PSMA4 3755.0
SNRNP40 3774.0
PSMD2 3775.0
PSMD8 3787.0
TFIP11 3793.0
PPIL1 3842.0
WDR12 3904.0
SNRPB2 3924.0
DHX8 3936.0
RPS27L 3962.0
SF3B3 3994.0
TYW1 3997.0
TCERG1 4048.0
CNOT11 4056.0
PRPF4 4084.0
CNOT4 4129.0
PSMA1 4142.0
SEH1L 4151.0
TNKS1BP1 4194.0
NXT1 4271.0
HNRNPM 4288.0
ACIN1 4372.0
THOC5 4390.0
DHX16 4409.0
RRP36 4450.0
GTF2H1 4500.0
EXOSC6 4538.0
MNAT1 4611.0
SMG7 4612.0
RPS9 4613.0
EXOSC2 4658.0
PPIG 4662.0
POLR2A 4709.0
RBM17 4724.0
LSM1 4726.0
NCL 4753.0
PPIL4 4763.0
THADA 4780.0
PRPF31 4826.0
POLR2D 4911.0
TRMT10A 4933.0
TRMT12 4965.0
AKT1 4980.0
DDX47 5064.0
SUPT5H 5133.0
WDR43 5292.0
NUDT21 5307.0
PRKCA 5314.0
CCAR1 5324.0
NUP62 5345.0
ADAR 5348.0
CSTF2T 5354.0
EPRS1 5374.0
WDR46 5401.0
NHP2 5491.0
FUS 5492.0
RBM7 5501.0
PPP2R2A 5566.0
RPS5 5602.0
SAP18 5603.0
MPHOSPH10 5687.0
PABPN1 5695.0
IGF2BP2 5699.0
SRSF8 5703.0
RPS25 5728.0
UPF2 5823.0
PSME4 5861.0
EDC4 5867.0
MAPKAPK2 5929.0
CNOT1 5986.0
RPL36 6037.0
RPL32 6039.0
GTF2H5 6090.0
PSMD6 6097.0
DUS2 6124.0
DCP2 6140.0
UTP11 6153.0
SMG6 6176.0
ERI1 6236.0
RPL8 6252.0
SRRT 6304.0
UTP20 6369.0
CDC5L 6399.0
GNL3 6407.0
RPS7 6408.0
SF3B1 6532.0
GTPBP3 6552.0
GTF2F2 6588.0
TRDMT1 6663.0
RPL19 6666.0
RPP40 6704.0
SKIC2 6713.0
GEMIN5 6721.0
UBC 6789.0
UPF1 6809.0
RBM5 6844.0
DHX15 6876.0
RANBP2 6991.0
DNAJC8 7018.0
URM1 7044.0
DDX52 7067.0
GLE1 7080.0
TRMT61A 7121.0
FIP1L1 7162.0
TP53RK 7243.0
HBS1L 7275.0
PSMC2 7343.0
CPSF6 7348.0
POLR2B 7360.0
SNRPA1 7396.0
WDR33 7481.0
DDX6 7524.0
BOP1 7546.0
CCNH 7559.0
PSMD1 7599.0
PES1 7605.0
ZMAT5 7712.0
USP39 7714.0
DDX41 7719.0
PELP1 7726.0
ZCRB1 7730.0
GTF2H4 7760.0
RPL26 7892.0
CLP1 7900.0
SNRPE 7982.0
MRM2 7991.0
PRKCD 7994.0
IGF2BP3 8142.0
TUT4 8189.0
PSMD11 8203.0
THOC6 8209.0
TFB1M 8235.0
SNRPC 8237.0
EXOSC3 8325.0
METTL1 8378.0
EIF4B 8380.0
SNRPD1 8388.0
GTF2H3 8389.0
ADAT3 8441.0
THUMPD1 8501.0
ZC3H11A 8533.0
HEATR1 8551.0
CRNKL1 8605.0
TRMT44 8611.0
CPSF2 8672.0
CSNK1D 8695.0
PSMB7 8791.0
APOBEC2 8812.0
SNRNP27 8905.0
PSMD3 8951.0
CASC3 9037.0
NOL12 9039.0
THOC1 9068.0
TRMT5 9156.0
SNU13 9203.0
PARN 9225.0
BMS1 9279.0
NUP37 9290.0
APOBEC3B 9309.0
CTNNBL1 9315.0
PSMD12 9401.0
PSMA6 9410.0
APOBEC4 9411.0
SNRNP48 9417.0
ANP32A 9478.0
ADARB1 9507.0
PRPF6 9519.0
EXOSC10 9535.0
TRA2B 9558.0
PDCD11 9639.0
NXF1 9831.0
PSMD4 9855.0
RBM22 9856.0
RPP25 9889.0
EIF4G1 9917.0
CWC25 9924.0
CNOT6L 10042.0
APOBEC1 10208.0
XRN2 10294.0
NOP14 10303.0
NOB1 10374.0
GEMIN4 10404.0
CSNK1E 10491.0
SKIC8 10622.0
RRP7A 10765.0
LSM10 10786.0
DDX39B 10802.0
PSMA8 10830.0
TNFSF13 10882.0
APOBEC3A 10985.0
SRSF12 11044.0
SNRNP35 11192.0
RPL10L 11201.0
RPL3L 11448.0
POLR2J 11645.0


REACTOME_REGULATION_OF_HMOX1_EXPRESSION_AND_ACTIVITY

REACTOME_REGULATION_OF_HMOX1_EXPRESSION_AND_ACTIVITY
1578
set REACTOME_REGULATION_OF_HMOX1_EXPRESSION_AND_ACTIVITY
setSize 5
pANOVA 0.00645
s.dist 0.703
p.adjustANOVA 0.23



Top enriched genes

Top 20 genes
GeneID Gene Rank
MAFK 10736
HM13 8799
BACH1 8026
NFE2L2 7805
HMOX1 6881

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MAFK 10736
HM13 8799
BACH1 8026
NFE2L2 7805
HMOX1 6881


REACTOME_TRNA_PROCESSING_IN_THE_NUCLEUS

REACTOME_TRNA_PROCESSING_IN_THE_NUCLEUS
1040
set REACTOME_TRNA_PROCESSING_IN_THE_NUCLEUS
setSize 58
pANOVA 0.00658
s.dist -0.206
p.adjustANOVA 0.23



Top enriched genes

Top 20 genes
GeneID Gene Rank
TSEN34 -8954
NUP153 -8270
RPP30 -8218
NUP155 -7615
NUP85 -7584
NUP58 -7085
NUP107 -7034
ZBTB8OS -6963
C2orf49 -6583
NUP50 -6545
RAN -6480
RTRAF -5778
NUP42 -5576
NUP35 -5516
SEC13 -4988
TPR -4960
POM121C -4951
POP7 -4938
NUP160 -3961
RTCB -3743

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TSEN34 -8954
NUP153 -8270
RPP30 -8218
NUP155 -7615
NUP85 -7584
NUP58 -7085
NUP107 -7034
ZBTB8OS -6963
C2orf49 -6583
NUP50 -6545
RAN -6480
RTRAF -5778
NUP42 -5576
NUP35 -5516
SEC13 -4988
TPR -4960
POM121C -4951
POP7 -4938
NUP160 -3961
RTCB -3743
NUP88 -3614
TRNT1 -3341
NUP54 -3047
TSEN54 -2697
POP4 -2494
AAAS -2469
RAE1 -2351
FAM98B -2054
NDC1 -1880
POP5 -1851
NUP205 -1548
NUP43 -1199
RPP38 -1007
ELAC2 -782
RPP21 -775
NUP210 -657
NUP133 -607
CPSF4 -555
NUP214 -368
POM121 -315
POP1 231
RPP14 445
XPOT 899
NUP98 1115
TSEN15 1393
TSEN2 1473
NUP188 1653
NUP93 2330
DDX1 2951
CPSF1 3132
RPPH1 3402
SEH1L 4151
NUP62 5345
RPP40 6704
RANBP2 6991
CLP1 7900
NUP37 9290
RPP25 9889


REACTOME_RRNA_PROCESSING

REACTOME_RRNA_PROCESSING
1148
set REACTOME_RRNA_PROCESSING
setSize 192
pANOVA 0.00693
s.dist -0.113
p.adjustANOVA 0.231



Top enriched genes

Top 20 genes
GeneID Gene Rank
PWP2 -9877.0
RPL7A -9849.0
RPL13A -9727.5
RPLP0 -9534.0
RPS3A -9277.0
RPL17 -9227.0
RPL3 -9097.0
RPL39L -8979.0
RPL29 -8969.0
RPL7 -8910.0
RPS18 -8789.0
RPS2 -8633.0
WDR75 -8497.0
RPSA -8411.0
RPL6 -8261.0
RPL34 -8230.0
LTV1 -8221.0
RPP30 -8218.0
IMP3 -8154.0
EMG1 -8117.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PWP2 -9877.0
RPL7A -9849.0
RPL13A -9727.5
RPLP0 -9534.0
RPS3A -9277.0
RPL17 -9227.0
RPL3 -9097.0
RPL39L -8979.0
RPL29 -8969.0
RPL7 -8910.0
RPS18 -8789.0
RPS2 -8633.0
WDR75 -8497.0
RPSA -8411.0
RPL6 -8261.0
RPL34 -8230.0
LTV1 -8221.0
RPP30 -8218.0
IMP3 -8154.0
EMG1 -8117.0
RPS13 -8088.0
RPL14 -8070.0
RPS12 -7983.0
RPL23A -7919.0
NOP56 -7755.0
RPL4 -7750.0
RPS20 -7733.0
RPS15A -7575.0
RPS15 -7544.0
DIMT1 -7352.0
RPL30 -7313.0
RPL13 -7308.0
RRP9 -7230.0
RPS6 -7197.0
RPL10A -7183.0
RPL5 -7176.0
MRM1 -7168.0
SENP3 -7159.0
RPS27 -7155.0
RPS23 -7108.0
TSR3 -6821.0
TRMT10C -6676.0
PNO1 -6228.0
DDX49 -6021.0
WDR36 -5947.0
RPS11 -5654.0
BUD23 -5557.0
ISG20L2 -5552.0
RPL18A -5504.0
RPS8 -5492.0
RPL27A -5422.0
UTP18 -5291.0
NIP7 -5279.0
MPHOSPH6 -5060.0
NSUN4 -4961.0
MRM3 -4940.0
RPL38 -4933.0
UTP14C -4725.0
UTP4 -4670.0
EXOSC5 -4639.0
FTSJ3 -4632.0
PRORP -4480.0
RPL21 -4309.0
DHX37 -4143.0
RPL11 -3914.0
RPL37 -3378.0
RPL28 -3334.0
DIS3 -3290.0
RPL22 -3268.0
DDX21 -3240.0
RPS10 -3097.0
RPL37A -2987.0
RPS28 -2923.0
RPS16 -2711.0
MTERF4 -2682.0
RPLP1 -2534.0
RPL36AL -2415.5
RPLP2 -2271.0
RPS3 -2211.0
RPL12 -2033.0
NOP2 -2032.0
TSR1 -2017.0
RPS14 -1898.0
RPL41 -1768.0
IMP4 -1760.0
RPL9 -1624.0
WDR3 -1128.0
RIOK1 -1039.0
UBA52 -1027.0
RPP38 -1007.0
TEX10 -999.0
EXOSC9 -984.0
MTREX -939.0
UTP15 -924.0
ELAC2 -782.0
RPP21 -775.0
NOP58 -772.0
WDR18 -576.0
DCAF13 -547.0
RPS27A -480.0
FBL -470.0
BYSL -237.0
TRMT112 -120.0
NOP10 -103.0
RPS19 -100.0
EBNA1BP2 -58.0
NOL11 43.0
RPL35A 155.0
FCF1 166.0
RPL27 186.0
EXOSC1 216.0
EXOSC4 259.0
RPL31 415.0
RPP14 445.0
RPL24 539.0
UTP6 786.0
EXOSC8 802.0
RPL22L1 834.0
UTP3 963.0
RPL18 1008.0
NAT10 1152.0
RIOK2 1259.0
RRP1 1571.0
UTP25 1879.0
RCL1 1908.0
FAU 2277.0
RPS21 2323.0
NOL6 2329.0
C1D 2378.0
RPL23 2439.0
TBL3 2630.0
RPS29 2769.0
RPL35 3004.0
EXOSC7 3005.0
RBM28 3035.0
GAR1 3119.0
NOC4L 3301.0
KRR1 3476.0
RPS24 3487.0
RIOK3 3512.0
NOL9 3550.0
RPS26 3565.0
RPL26L1 3578.0
RPL15 3621.0
WDR12 3904.0
RPS27L 3962.0
RRP36 4450.0
EXOSC6 4538.0
RPS9 4613.0
EXOSC2 4658.0
NCL 4753.0
DDX47 5064.0
WDR43 5292.0
WDR46 5401.0
NHP2 5491.0
RPS5 5602.0
MPHOSPH10 5687.0
RPS25 5728.0
RPL36 6037.0
RPL32 6039.0
UTP11 6153.0
ERI1 6236.0
RPL8 6252.0
UTP20 6369.0
GNL3 6407.0
RPS7 6408.0
RPL19 6666.0
RPP40 6704.0
DDX52 7067.0
BOP1 7546.0
PES1 7605.0
PELP1 7726.0
RPL26 7892.0
MRM2 7991.0
TFB1M 8235.0
EXOSC3 8325.0
THUMPD1 8501.0
HEATR1 8551.0
CSNK1D 8695.0
NOL12 9039.0
SNU13 9203.0
BMS1 9279.0
EXOSC10 9535.0
PDCD11 9639.0
RPP25 9889.0
XRN2 10294.0
NOP14 10303.0
NOB1 10374.0
CSNK1E 10491.0
RRP7A 10765.0
RPL10L 11201.0
RPL3L 11448.0


REACTOME_RHOV_GTPASE_CYCLE

REACTOME_RHOV_GTPASE_CYCLE
1383
set REACTOME_RHOV_GTPASE_CYCLE
setSize 36
pANOVA 0.00701
s.dist 0.26
p.adjustANOVA 0.231



Top enriched genes

Top 20 genes
GeneID Gene Rank
EPHA2 10946
CEP97 10579
PARD6B 10497
PAK4 10196
TXNL1 9303
GIT1 8577
PEAK1 8366
TPM4 8117
ARHGAP12 7293
MAP3K11 7150
PAK2 6918
CCP110 6769
CDC42 6736
DEPDC1B 6553
TPM3 6075
SPTAN1 5767
PIK3R1 5287
PAK1 5067
SH3RF1 4972
CLTC 4928

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
EPHA2 10946.0
CEP97 10579.0
PARD6B 10497.0
PAK4 10196.0
TXNL1 9303.0
GIT1 8577.0
PEAK1 8366.0
TPM4 8117.0
ARHGAP12 7293.0
MAP3K11 7150.0
PAK2 6918.0
CCP110 6769.0
CDC42 6736.0
DEPDC1B 6553.0
TPM3 6075.0
SPTAN1 5767.0
PIK3R1 5287.0
PAK1 5067.0
SH3RF1 4972.0
CLTC 4928.0
SPTBN1 3971.0
MYO9A 3081.0
WASL 2921.0
DST 2692.0
ZNF512B 1758.0
VANGL1 206.0
NCK1 75.0
PAK6 -2068.0
ARHGEF7 -2181.0
RHOV -3045.0
NCK2 -3250.0
GIT2 -3264.0
WDR6 -4667.0
DLG5 -4740.0
IQGAP1 -6084.0
PARD6A -7218.5


REACTOME_DISEASES_OF_IMMUNE_SYSTEM

REACTOME_DISEASES_OF_IMMUNE_SYSTEM
856
set REACTOME_DISEASES_OF_IMMUNE_SYSTEM
setSize 29
pANOVA 0.00704
s.dist 0.289
p.adjustANOVA 0.231



Top enriched genes

Top 20 genes
GeneID Gene Rank
S100A8 11501
TLR4 11228
TLR1 11039
S100A9 10944
RELA 10539
TLR10 9280
TLR6 8756
LY96 8736
NFKBIA 8320
HMGB1 8140
MYD88 7926
S100A1 7756
IKBKB 7170
TRAF3 6357
FGB 5732
CD14 5691
UNC93B1 5582
TIRAP 4274
TLR3 3799
CHUK 3407

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
S100A8 11501
TLR4 11228
TLR1 11039
S100A9 10944
RELA 10539
TLR10 9280
TLR6 8756
LY96 8736
NFKBIA 8320
HMGB1 8140
MYD88 7926
S100A1 7756
IKBKB 7170
TRAF3 6357
FGB 5732
CD14 5691
UNC93B1 5582
TIRAP 4274
TLR3 3799
CHUK 3407
CD36 2158
TICAM1 -2846
IRAK4 -3377
TLR2 -3985
NFKB2 -4827
FGG -5317
NFKB1 -6991
TLR5 -8131
FGA -10100


Here is the session info with all the versions of packages used.

sessionInfo()
## R version 4.3.2 (2023-10-31)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.3 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3 
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so;  LAPACK version 3.10.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Etc/UTC
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.3.3                                      
##  [2] GGally_2.2.0                                       
##  [3] ggplot2_3.4.4                                      
##  [4] reshape2_1.4.4                                     
##  [5] gtools_3.9.5                                       
##  [6] tibble_3.2.1                                       
##  [7] dplyr_1.1.4                                        
##  [8] echarts4r_0.4.5                                    
##  [9] png_0.1-8                                          
## [10] gridExtra_2.3                                      
## [11] missMethyl_1.36.0                                  
## [12] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.1 
## [13] beeswarm_0.4.0                                     
## [14] kableExtra_1.3.4                                   
## [15] gplots_3.1.3                                       
## [16] mitch_1.15.0                                       
## [17] tictoc_1.2                                         
## [18] HGNChelper_0.8.1                                   
## [19] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [20] IlluminaHumanMethylation450kmanifest_0.4.0         
## [21] minfi_1.48.0                                       
## [22] bumphunter_1.44.0                                  
## [23] locfit_1.5-9.8                                     
## [24] iterators_1.0.14                                   
## [25] foreach_1.5.2                                      
## [26] Biostrings_2.70.1                                  
## [27] XVector_0.42.0                                     
## [28] SummarizedExperiment_1.32.0                        
## [29] Biobase_2.62.0                                     
## [30] MatrixGenerics_1.14.0                              
## [31] matrixStats_1.2.0                                  
## [32] GenomicRanges_1.54.1                               
## [33] GenomeInfoDb_1.38.2                                
## [34] IRanges_2.36.0                                     
## [35] S4Vectors_0.40.2                                   
## [36] BiocGenerics_0.48.1                                
## [37] eulerr_7.0.0                                       
## [38] limma_3.58.1                                       
## 
## loaded via a namespace (and not attached):
##   [1] splines_4.3.2             later_1.3.2              
##   [3] BiocIO_1.12.0             bitops_1.0-7             
##   [5] filelock_1.0.3            preprocessCore_1.64.0    
##   [7] XML_3.99-0.16             lifecycle_1.0.4          
##   [9] lattice_0.22-5            MASS_7.3-60              
##  [11] base64_2.0.1              scrime_1.3.5             
##  [13] magrittr_2.0.3            sass_0.4.8               
##  [15] rmarkdown_2.25            jquerylib_0.1.4          
##  [17] yaml_2.3.8                httpuv_1.6.13            
##  [19] doRNG_1.8.6               askpass_1.2.0            
##  [21] DBI_1.1.3                 RColorBrewer_1.1-3       
##  [23] abind_1.4-5               zlibbioc_1.48.0          
##  [25] rvest_1.0.3               quadprog_1.5-8           
##  [27] purrr_1.0.2               RCurl_1.98-1.13          
##  [29] rappdirs_0.3.3            GenomeInfoDbData_1.2.11  
##  [31] genefilter_1.84.0         annotate_1.80.0          
##  [33] svglite_2.1.3             DelayedMatrixStats_1.24.0
##  [35] codetools_0.2-19          DelayedArray_0.28.0      
##  [37] xml2_1.3.6                tidyselect_1.2.0         
##  [39] beanplot_1.3.1            BiocFileCache_2.10.1     
##  [41] webshot_0.5.5             illuminaio_0.44.0        
##  [43] GenomicAlignments_1.38.0  jsonlite_1.8.8           
##  [45] multtest_2.58.0           ellipsis_0.3.2           
##  [47] survival_3.5-7            systemfonts_1.0.5        
##  [49] tools_4.3.2               progress_1.2.3           
##  [51] Rcpp_1.0.11               glue_1.6.2               
##  [53] SparseArray_1.2.2         xfun_0.41                
##  [55] HDF5Array_1.30.0          withr_2.5.2              
##  [57] fastmap_1.1.1             rhdf5filters_1.14.1      
##  [59] fansi_1.0.6               openssl_2.1.1            
##  [61] caTools_1.18.2            digest_0.6.33            
##  [63] R6_2.5.1                  mime_0.12                
##  [65] colorspace_2.1-0          biomaRt_2.58.0           
##  [67] RSQLite_2.3.4             utf8_1.2.4               
##  [69] tidyr_1.3.0               generics_0.1.3           
##  [71] data.table_1.14.10        rtracklayer_1.62.0       
##  [73] prettyunits_1.2.0         httr_1.4.7               
##  [75] htmlwidgets_1.6.4         S4Arrays_1.2.0           
##  [77] ggstats_0.5.1             pkgconfig_2.0.3          
##  [79] gtable_0.3.4              blob_1.2.4               
##  [81] siggenes_1.76.0           htmltools_0.5.7          
##  [83] scales_1.3.0              rstudioapi_0.15.0        
##  [85] knitr_1.45                tzdb_0.4.0               
##  [87] rjson_0.2.21              nlme_3.1-163             
##  [89] curl_5.2.0                org.Hs.eg.db_3.18.0      
##  [91] cachem_1.0.8              rhdf5_2.46.1             
##  [93] stringr_1.5.1             KernSmooth_2.23-22       
##  [95] AnnotationDbi_1.64.1      restfulr_0.0.15          
##  [97] GEOquery_2.70.0           pillar_1.9.0             
##  [99] grid_4.3.2                reshape_0.8.9            
## [101] vctrs_0.6.5               promises_1.2.1           
## [103] dbplyr_2.4.0              xtable_1.8-4             
## [105] evaluate_0.23             readr_2.1.4              
## [107] GenomicFeatures_1.54.1    cli_3.6.2                
## [109] compiler_4.3.2            Rsamtools_2.18.0         
## [111] rlang_1.1.2               crayon_1.5.2             
## [113] rngtools_1.5.2            nor1mix_1.3-2            
## [115] mclust_6.0.1              plyr_1.8.9               
## [117] stringi_1.8.3             viridisLite_0.4.2        
## [119] BiocParallel_1.36.0       munsell_0.5.0            
## [121] Matrix_1.6-1.1            hms_1.1.3                
## [123] sparseMatrixStats_1.14.0  bit64_4.0.5              
## [125] Rhdf5lib_1.24.1           KEGGREST_1.42.0          
## [127] statmod_1.5.0             shiny_1.8.0              
## [129] highr_0.10                memoise_2.0.1            
## [131] bslib_0.6.1               bit_4.0.5

END of report