date generated: 2024-01-18

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch
x
A1BG -0.0016282
A1BG-AS1 -0.0019914
A1CF 0.0018986
A2M -0.0008026
A2M-AS1 -0.0051522
A2ML1 0.0006945

Here are some metrics about the input data profile:

Profiling data metrics
Profile metrics
num_genesets 1654
num_genes_in_profile 22007
duplicated_genes_present 0
num_profile_genes_in_sets 10383
num_profile_genes_not_in_sets 11624

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets: c2.cp.reactome.v2023.1.Hs.symbols.gmt
Gene set metrics
Gene sets metrics
num_genesets 1654
num_genesets_excluded 365
num_genesets_included 1289

Differential pathway expression


Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

## Warning in kable_styling(., "hover", full_width = FALSE): Please specify format
## in kable. kableExtra can customize either HTML or LaTeX outputs. See
## https://haozhu233.github.io/kableExtra/ for details.
set setSize pANOVA s.dist p.adjustANOVA
REACTOME OLFACTORY SIGNALING PATHWAY 348 2.72e-13 0.2280 2.83e-10
REACTOME SENSORY PERCEPTION 555 3.45e-13 0.1810 2.83e-10
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES 55 3.42e-07 0.3970 1.87e-04
REACTOME INTERLEUKIN 12 SIGNALING 43 1.95e-05 -0.3760 7.99e-03
REACTOME CELLULAR RESPONSES TO STIMULI 779 2.52e-05 -0.0887 8.27e-03
REACTOME INTERLEUKIN 12 FAMILY SIGNALING 53 4.39e-05 -0.3240 1.20e-02
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION 1356 8.23e-05 -0.0637 1.76e-02
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM 688 8.69e-05 -0.0878 1.76e-02
REACTOME VISUAL PHOTOTRANSDUCTION 93 9.67e-05 0.2340 1.76e-02
REACTOME PEPTIDE LIGAND BINDING RECEPTORS 188 1.53e-04 0.1600 2.52e-02
REACTOME HIV LIFE CYCLE 145 1.82e-04 -0.1800 2.72e-02
REACTOME INFECTIOUS DISEASE 910 3.19e-04 -0.0704 4.10e-02
REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS 312 3.25e-04 0.1180 4.10e-02
REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION 35 3.74e-04 -0.3470 4.38e-02
REACTOME HIV INFECTION 223 5.44e-04 -0.1340 5.96e-02
REACTOME INITIAL TRIGGERING OF COMPLEMENT 21 6.71e-04 0.4290 6.56e-02
REACTOME SIGNALING BY INTERLEUKINS 444 6.79e-04 -0.0940 6.56e-02
REACTOME CREATION OF C4 AND C2 ACTIVATORS 14 9.73e-04 0.5090 8.88e-02
REACTOME NGF STIMULATED TRANSCRIPTION 38 1.14e-03 -0.3050 9.87e-02
REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION 8 1.27e-03 0.6580 1.04e-01
REACTOME ASPIRIN ADME 42 1.68e-03 0.2800 1.27e-01
REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE 5 1.72e-03 0.8090 1.27e-01
REACTOME COMPLEMENT CASCADE 54 1.78e-03 0.2460 1.27e-01
REACTOME CELLULAR SENESCENCE 189 1.85e-03 -0.1310 1.27e-01
REACTOME SIGNALING BY NTRKS 132 2.03e-03 -0.1560 1.32e-01
REACTOME SIGNALING BY ERYTHROPOIETIN 25 2.16e-03 -0.3540 1.32e-01
REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION 23 2.17e-03 0.3690 1.32e-01
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION 81 2.27e-03 -0.1960 1.33e-01
REACTOME HCMV INFECTION 152 2.43e-03 -0.1420 1.37e-01
REACTOME TRANSCRIPTIONAL REGULATION BY TP53 351 2.60e-03 -0.0936 1.42e-01
REACTOME AMINO ACID CONJUGATION 9 2.82e-03 0.5750 1.47e-01
REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE 35 2.86e-03 -0.2910 1.47e-01
REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES 80 3.06e-03 -0.1910 1.48e-01
REACTOME RHOG GTPASE CYCLE 71 3.09e-03 -0.2030 1.48e-01
REACTOME ESTROGEN DEPENDENT GENE EXPRESSION 140 3.25e-03 -0.1440 1.48e-01
REACTOME GPCR LIGAND BINDING 444 3.44e-03 0.0810 1.48e-01
REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION 59 3.54e-03 -0.2200 1.48e-01
REACTOME PHOSPHOLIPID METABOLISM 201 3.57e-03 -0.1190 1.48e-01
REACTOME TNF SIGNALING 54 3.60e-03 -0.2290 1.48e-01
REACTOME DEUBIQUITINATION 260 3.67e-03 -0.1050 1.48e-01
REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX 39 3.69e-03 -0.2690 1.48e-01
REACTOME CELL CYCLE MITOTIC 539 4.35e-03 -0.0718 1.67e-01
REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES 7 4.49e-03 -0.6200 1.67e-01
REACTOME CREB3 FACTORS ACTIVATE GENES 8 4.51e-03 0.5800 1.67e-01
REACTOME DAP12 SIGNALING 27 4.58e-03 -0.3150 1.67e-01
REACTOME HOST INTERACTIONS OF HIV FACTORS 127 4.82e-03 -0.1450 1.71e-01
REACTOME INTERLEUKIN 35 SIGNALLING 12 4.94e-03 -0.4690 1.71e-01
REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT 159 5.06e-03 -0.1290 1.71e-01
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION 361 5.19e-03 -0.0856 1.71e-01
REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS 12 5.27e-03 0.4650 1.71e-01


Results (complete table)


Click HERE to show results for all gene sets

Complete results
set setSize pANOVA s.dist p.adjustANOVA
REACTOME OLFACTORY SIGNALING PATHWAY 348 2.72e-13 2.28e-01 2.83e-10
REACTOME SENSORY PERCEPTION 555 3.45e-13 1.81e-01 2.83e-10
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES 55 3.42e-07 3.97e-01 1.87e-04
REACTOME INTERLEUKIN 12 SIGNALING 43 1.95e-05 -3.76e-01 7.99e-03
REACTOME CELLULAR RESPONSES TO STIMULI 779 2.52e-05 -8.87e-02 8.27e-03
REACTOME INTERLEUKIN 12 FAMILY SIGNALING 53 4.39e-05 -3.24e-01 1.20e-02
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION 1356 8.23e-05 -6.37e-02 1.76e-02
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM 688 8.69e-05 -8.78e-02 1.76e-02
REACTOME VISUAL PHOTOTRANSDUCTION 93 9.67e-05 2.34e-01 1.76e-02
REACTOME PEPTIDE LIGAND BINDING RECEPTORS 188 1.53e-04 1.60e-01 2.52e-02
REACTOME HIV LIFE CYCLE 145 1.82e-04 -1.80e-01 2.72e-02
REACTOME INFECTIOUS DISEASE 910 3.19e-04 -7.04e-02 4.10e-02
REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS 312 3.25e-04 1.18e-01 4.10e-02
REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION 35 3.74e-04 -3.47e-01 4.38e-02
REACTOME HIV INFECTION 223 5.44e-04 -1.34e-01 5.96e-02
REACTOME INITIAL TRIGGERING OF COMPLEMENT 21 6.71e-04 4.29e-01 6.56e-02
REACTOME SIGNALING BY INTERLEUKINS 444 6.79e-04 -9.40e-02 6.56e-02
REACTOME CREATION OF C4 AND C2 ACTIVATORS 14 9.73e-04 5.09e-01 8.88e-02
REACTOME NGF STIMULATED TRANSCRIPTION 38 1.14e-03 -3.05e-01 9.87e-02
REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION 8 1.27e-03 6.58e-01 1.04e-01
REACTOME ASPIRIN ADME 42 1.68e-03 2.80e-01 1.27e-01
REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE 5 1.72e-03 8.09e-01 1.27e-01
REACTOME COMPLEMENT CASCADE 54 1.78e-03 2.46e-01 1.27e-01
REACTOME CELLULAR SENESCENCE 189 1.85e-03 -1.31e-01 1.27e-01
REACTOME SIGNALING BY NTRKS 132 2.03e-03 -1.56e-01 1.32e-01
REACTOME SIGNALING BY ERYTHROPOIETIN 25 2.16e-03 -3.54e-01 1.32e-01
REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION 23 2.17e-03 3.69e-01 1.32e-01
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION 81 2.27e-03 -1.96e-01 1.33e-01
REACTOME HCMV INFECTION 152 2.43e-03 -1.42e-01 1.37e-01
REACTOME TRANSCRIPTIONAL REGULATION BY TP53 351 2.60e-03 -9.36e-02 1.42e-01
REACTOME AMINO ACID CONJUGATION 9 2.82e-03 5.75e-01 1.47e-01
REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE 35 2.86e-03 -2.91e-01 1.47e-01
REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES 80 3.06e-03 -1.91e-01 1.48e-01
REACTOME RHOG GTPASE CYCLE 71 3.09e-03 -2.03e-01 1.48e-01
REACTOME ESTROGEN DEPENDENT GENE EXPRESSION 140 3.25e-03 -1.44e-01 1.48e-01
REACTOME GPCR LIGAND BINDING 444 3.44e-03 8.10e-02 1.48e-01
REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION 59 3.54e-03 -2.20e-01 1.48e-01
REACTOME PHOSPHOLIPID METABOLISM 201 3.57e-03 -1.19e-01 1.48e-01
REACTOME TNF SIGNALING 54 3.60e-03 -2.29e-01 1.48e-01
REACTOME DEUBIQUITINATION 260 3.67e-03 -1.05e-01 1.48e-01
REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX 39 3.69e-03 -2.69e-01 1.48e-01
REACTOME CELL CYCLE MITOTIC 539 4.35e-03 -7.18e-02 1.67e-01
REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES 7 4.49e-03 -6.20e-01 1.67e-01
REACTOME CREB3 FACTORS ACTIVATE GENES 8 4.51e-03 5.80e-01 1.67e-01
REACTOME DAP12 SIGNALING 27 4.58e-03 -3.15e-01 1.67e-01
REACTOME HOST INTERACTIONS OF HIV FACTORS 127 4.82e-03 -1.45e-01 1.71e-01
REACTOME INTERLEUKIN 35 SIGNALLING 12 4.94e-03 -4.69e-01 1.71e-01
REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT 159 5.06e-03 -1.29e-01 1.71e-01
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION 361 5.19e-03 -8.56e-02 1.71e-01
REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS 12 5.27e-03 4.65e-01 1.71e-01
REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS 418 5.40e-03 -7.93e-02 1.71e-01
REACTOME RAS SIGNALING DOWNSTREAM OF NF1 LOSS OF FUNCTION VARIANTS 7 5.52e-03 -6.06e-01 1.71e-01
REACTOME ADAPTIVE IMMUNE SYSTEM 729 5.69e-03 -6.01e-02 1.71e-01
REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES 14 5.71e-03 -4.27e-01 1.71e-01
REACTOME ANTIMICROBIAL PEPTIDES 76 5.74e-03 1.83e-01 1.71e-01
REACTOME ASPARAGINE N LINKED GLYCOSYLATION 299 6.03e-03 -9.23e-02 1.75e-01
REACTOME DNA DAMAGE RECOGNITION IN GG NER 36 6.06e-03 -2.64e-01 1.75e-01
REACTOME CELL CYCLE 666 6.39e-03 -6.19e-02 1.79e-01
REACTOME P38MAPK EVENTS 13 6.43e-03 -4.36e-01 1.79e-01
REACTOME MEMBRANE TRAFFICKING 603 6.64e-03 -6.47e-02 1.82e-01
REACTOME HATS ACETYLATE HISTONES 129 6.98e-03 -1.38e-01 1.88e-01
REACTOME METABOLISM OF FAT SOLUBLE VITAMINS 46 7.42e-03 2.28e-01 1.94e-01
REACTOME RUNX3 REGULATES P14 ARF 10 7.52e-03 -4.88e-01 1.94e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1 229 7.59e-03 -1.02e-01 1.94e-01
REACTOME COPI MEDIATED ANTEROGRADE TRANSPORT 101 7.72e-03 -1.53e-01 1.94e-01
REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION 90 7.90e-03 -1.62e-01 1.94e-01
REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION 296 7.91e-03 -8.97e-02 1.94e-01
REACTOME RESPONSE TO METAL IONS 14 8.07e-03 -4.09e-01 1.94e-01
REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS 123 8.14e-03 -1.38e-01 1.94e-01
REACTOME INTERFERON SIGNALING 193 8.34e-03 -1.10e-01 1.96e-01
REACTOME NUCLEAR ENVELOPE NE REASSEMBLY 74 8.69e-03 -1.76e-01 1.96e-01
REACTOME DIGESTION OF DIETARY CARBOHYDRATE 6 8.71e-03 6.18e-01 1.96e-01
REACTOME REGULATION OF PTEN GENE TRANSCRIPTION 59 8.77e-03 -1.97e-01 1.96e-01
REACTOME SIGNALLING TO ERKS 34 8.85e-03 -2.59e-01 1.96e-01
REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE 19 9.63e-03 -3.43e-01 2.11e-01
REACTOME RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS 5 1.06e-02 -6.60e-01 2.27e-01
REACTOME INTERLEUKIN 20 FAMILY SIGNALING 25 1.07e-02 -2.95e-01 2.27e-01
REACTOME ENDOSOMAL VACUOLAR PATHWAY 11 1.12e-02 -4.42e-01 2.36e-01
REACTOME TRANSCRIPTIONAL REGULATION BY MECP2 60 1.14e-02 -1.89e-01 2.36e-01
REACTOME AUTOPHAGY 144 1.15e-02 -1.22e-01 2.37e-01
REACTOME INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS 37 1.19e-02 -2.39e-01 2.41e-01
REACTOME HCMV LATE EVENTS 110 1.29e-02 -1.37e-01 2.58e-01
REACTOME CLATHRIN MEDIATED ENDOCYTOSIS 139 1.32e-02 -1.22e-01 2.61e-01
REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE 11 1.35e-02 4.30e-01 2.63e-01
REACTOME CALNEXIN CALRETICULIN CYCLE 26 1.36e-02 -2.80e-01 2.63e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES 11 1.39e-02 4.28e-01 2.65e-01
REACTOME INTERLEUKIN 7 SIGNALING 31 1.46e-02 -2.53e-01 2.73e-01
REACTOME ER QUALITY CONTROL COMPARTMENT ERQC 21 1.47e-02 -3.08e-01 2.73e-01
REACTOME UREA CYCLE 9 1.50e-02 -4.68e-01 2.73e-01
REACTOME HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR IN THE PRESENCE OF LIGAND 55 1.51e-02 -1.89e-01 2.73e-01
REACTOME HCMV EARLY EVENTS 128 1.54e-02 -1.24e-01 2.73e-01
REACTOME HEME SIGNALING 47 1.54e-02 -2.04e-01 2.73e-01
REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3 679 1.55e-02 -5.45e-02 2.73e-01
REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS 42 1.56e-02 2.16e-01 2.73e-01
REACTOME DIGESTION AND ABSORPTION 22 1.58e-02 2.97e-01 2.74e-01
REACTOME INTERLEUKIN 21 SIGNALING 9 1.62e-02 -4.63e-01 2.76e-01
REACTOME SIGNALING BY GPCR 673 1.69e-02 5.40e-02 2.76e-01
REACTOME METALLOTHIONEINS BIND METALS 11 1.69e-02 -4.16e-01 2.76e-01
REACTOME REPRESSION OF WNT TARGET GENES 14 1.70e-02 -3.68e-01 2.76e-01
REACTOME UB SPECIFIC PROCESSING PROTEASES 187 1.74e-02 -1.01e-01 2.76e-01
REACTOME ERYTHROPOIETIN ACTIVATES RAS 14 1.74e-02 -3.67e-01 2.76e-01
REACTOME AMINO ACIDS REGULATE MTORC1 53 1.75e-02 -1.89e-01 2.76e-01
REACTOME ESR MEDIATED SIGNALING 210 1.75e-02 -9.51e-02 2.76e-01
REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER 81 1.76e-02 -1.53e-01 2.76e-01
REACTOME HYALURONAN UPTAKE AND DEGRADATION 12 1.79e-02 3.95e-01 2.76e-01
REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT 31 1.81e-02 -2.45e-01 2.76e-01
REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS 35 1.81e-02 -2.31e-01 2.76e-01
REACTOME INTERLEUKIN 9 SIGNALING 7 1.82e-02 -5.16e-01 2.76e-01
REACTOME TRNA PROCESSING IN THE NUCLEUS 58 1.86e-02 -1.79e-01 2.79e-01
REACTOME SIGNALING BY PTK6 54 1.87e-02 -1.85e-01 2.79e-01
REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS 100 1.95e-02 -1.35e-01 2.87e-01
REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS 6 1.96e-02 5.50e-01 2.87e-01
REACTOME G ALPHA I SIGNALLING EVENTS 304 2.04e-02 7.73e-02 2.94e-01
REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT 222 2.05e-02 -9.02e-02 2.94e-01
REACTOME POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION 27 2.08e-02 -2.57e-01 2.94e-01
REACTOME MIRO GTPASE CYCLE 8 2.09e-02 -4.71e-01 2.94e-01
REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX 85 2.09e-02 -1.45e-01 2.94e-01
REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 22 2.14e-02 -2.83e-01 2.95e-01
REACTOME RAC3 GTPASE CYCLE 85 2.14e-02 -1.44e-01 2.95e-01
REACTOME RAC2 GTPASE CYCLE 81 2.21e-02 -1.47e-01 3.02e-01
REACTOME CD163 MEDIATING AN ANTI INFLAMMATORY RESPONSE 9 2.26e-02 -4.39e-01 3.03e-01
REACTOME MET RECEPTOR RECYCLING 10 2.26e-02 -4.17e-01 3.03e-01
REACTOME DISEASES OF DNA REPAIR 51 2.29e-02 -1.84e-01 3.03e-01
REACTOME FCERI MEDIATED MAPK ACTIVATION 32 2.30e-02 -2.32e-01 3.03e-01
REACTOME FORMATION OF THE CORNIFIED ENVELOPE 125 2.32e-02 1.18e-01 3.03e-01
REACTOME CYTOPROTECTION BY HMOX1 59 2.39e-02 -1.70e-01 3.03e-01
REACTOME PLASMA LIPOPROTEIN REMODELING 33 2.39e-02 2.27e-01 3.03e-01
REACTOME TRNA PROCESSING 105 2.40e-02 -1.28e-01 3.03e-01
REACTOME APOPTOSIS 173 2.40e-02 -9.95e-02 3.03e-01
REACTOME BILE ACID AND BILE SALT METABOLISM 45 2.45e-02 1.94e-01 3.03e-01
REACTOME DEATH RECEPTOR SIGNALING 143 2.49e-02 -1.09e-01 3.03e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION 89 2.50e-02 -1.37e-01 3.03e-01
REACTOME M PHASE 398 2.50e-02 -6.55e-02 3.03e-01
REACTOME CYTOCHROME C MEDIATED APOPTOTIC RESPONSE 12 2.51e-02 -3.74e-01 3.03e-01
REACTOME CHROMATIN MODIFYING ENZYMES 252 2.51e-02 -8.19e-02 3.03e-01
REACTOME CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY 25 2.53e-02 -2.58e-01 3.03e-01
REACTOME DEVELOPMENTAL BIOLOGY 1115 2.53e-02 -3.97e-02 3.03e-01
REACTOME OXIDATIVE STRESS INDUCED SENESCENCE 118 2.58e-02 -1.19e-01 3.07e-01
REACTOME INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING 103 2.64e-02 -1.27e-01 3.11e-01
REACTOME TRANSPORT OF NUCLEOTIDE SUGARS 8 2.66e-02 -4.53e-01 3.11e-01
REACTOME PTEN REGULATION 135 2.77e-02 -1.10e-01 3.23e-01
REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV 1 INFECTION 5 2.80e-02 -5.67e-01 3.24e-01
REACTOME RHOH GTPASE CYCLE 37 2.87e-02 -2.08e-01 3.25e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG 7 2.88e-02 -4.77e-01 3.25e-01
REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC 198 2.89e-02 -9.00e-02 3.25e-01
REACTOME EARLY PHASE OF HIV LIFE CYCLE 14 2.90e-02 -3.37e-01 3.25e-01
REACTOME DIGESTION 17 2.91e-02 3.06e-01 3.25e-01
REACTOME CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS 100 2.96e-02 -1.26e-01 3.26e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS 34 2.96e-02 2.16e-01 3.26e-01
REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS 68 2.99e-02 -1.52e-01 3.26e-01
REACTOME RHOT1 GTPASE CYCLE 5 3.01e-02 -5.60e-01 3.26e-01
REACTOME SUMOYLATION 179 3.02e-02 -9.39e-02 3.26e-01
REACTOME MTORC1 MEDIATED SIGNALLING 23 3.10e-02 -2.60e-01 3.31e-01
REACTOME BUDDING AND MATURATION OF HIV VIRION 28 3.14e-02 -2.35e-01 3.31e-01
REACTOME HDR THROUGH HOMOLOGOUS RECOMBINATION HRR 66 3.17e-02 -1.53e-01 3.31e-01
REACTOME MET ACTIVATES PTK2 SIGNALING 30 3.18e-02 2.26e-01 3.31e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES 10 3.18e-02 3.92e-01 3.31e-01
REACTOME LATE SARS COV 2 INFECTION EVENTS 67 3.22e-02 -1.51e-01 3.31e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL 24 3.23e-02 2.52e-01 3.31e-01
REACTOME SIGNALLING TO RAS 20 3.24e-02 -2.76e-01 3.31e-01
REACTOME MTOR SIGNALLING 40 3.25e-02 -1.95e-01 3.31e-01
REACTOME SUMOYLATION OF UBIQUITINYLATION PROTEINS 39 3.27e-02 -1.98e-01 3.31e-01
REACTOME INTERLEUKIN 36 PATHWAY 7 3.30e-02 4.65e-01 3.32e-01
REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES 18 3.35e-02 2.89e-01 3.34e-01
REACTOME BICARBONATE TRANSPORTERS 10 3.37e-02 3.88e-01 3.34e-01
REACTOME TRIF MEDIATED PROGRAMMED CELL DEATH 9 3.38e-02 -4.09e-01 3.34e-01
REACTOME CELLULAR RESPONSE TO HEAT STRESS 99 3.40e-02 -1.23e-01 3.34e-01
REACTOME NUCLEAR IMPORT OF REV PROTEIN 34 3.43e-02 -2.10e-01 3.34e-01
REACTOME SIGNALING BY FGFR4 IN DISEASE 11 3.46e-02 -3.68e-01 3.34e-01
REACTOME DAP12 INTERACTIONS 37 3.46e-02 -2.01e-01 3.34e-01
REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION 36 3.55e-02 -2.03e-01 3.40e-01
REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK 28 3.62e-02 -2.29e-01 3.45e-01
REACTOME SARS COV INFECTIONS 392 3.65e-02 -6.15e-02 3.45e-01
REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP 41 3.66e-02 -1.89e-01 3.45e-01
REACTOME SUMOYLATION OF DNA REPLICATION PROTEINS 46 3.67e-02 -1.78e-01 3.45e-01
REACTOME TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX 14 3.73e-02 -3.21e-01 3.48e-01
REACTOME FORMATION OF XYLULOSE 5 PHOSPHATE 5 3.83e-02 5.35e-01 3.55e-01
REACTOME SULFIDE OXIDATION TO SULFATE 6 3.85e-02 -4.88e-01 3.55e-01
REACTOME GASTRULATION 49 3.92e-02 -1.70e-01 3.57e-01
REACTOME SIGNALING BY FGFR1 IN DISEASE 38 3.95e-02 -1.93e-01 3.57e-01
REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS 111 3.95e-02 -1.13e-01 3.57e-01
REACTOME ASPARTATE AND ASPARAGINE METABOLISM 11 3.95e-02 -3.58e-01 3.57e-01
REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 11 4.08e-02 3.56e-01 3.64e-01
REACTOME MET ACTIVATES RAP1 AND RAC1 11 4.09e-02 -3.56e-01 3.64e-01
REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS 33 4.10e-02 -2.06e-01 3.64e-01
REACTOME METABOLISM OF CARBOHYDRATES 279 4.16e-02 -7.09e-02 3.66e-01
REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS 188 4.19e-02 -8.60e-02 3.66e-01
REACTOME ACTIVATION OF RAS IN B CELLS 5 4.27e-02 -5.23e-01 3.66e-01
REACTOME APOPTOTIC FACTOR MEDIATED RESPONSE 19 4.28e-02 -2.68e-01 3.66e-01
REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III 31 4.31e-02 -2.10e-01 3.66e-01
REACTOME G ALPHA S SIGNALLING EVENTS 155 4.35e-02 9.40e-02 3.66e-01
REACTOME GLUCONEOGENESIS 33 4.36e-02 -2.03e-01 3.66e-01
REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY 46 4.37e-02 1.72e-01 3.66e-01
REACTOME INTERLEUKIN 27 SIGNALING 11 4.41e-02 -3.51e-01 3.66e-01
REACTOME INTERLEUKIN 2 FAMILY SIGNALING 40 4.48e-02 -1.83e-01 3.66e-01
REACTOME PROGRAMMED CELL DEATH 204 4.49e-02 -8.14e-02 3.66e-01
REACTOME HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE 43 4.50e-02 -1.77e-01 3.66e-01
REACTOME NUCLEOTIDE EXCISION REPAIR 107 4.52e-02 -1.12e-01 3.66e-01
REACTOME SIGNALING BY KIT IN DISEASE 20 4.54e-02 -2.58e-01 3.66e-01
REACTOME EARLY SARS COV 2 INFECTION EVENTS 34 4.56e-02 -1.98e-01 3.66e-01
REACTOME UPTAKE OF DIETARY COBALAMINS INTO ENTEROCYTES 9 4.59e-02 3.84e-01 3.66e-01
REACTOME PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1 9 4.59e-02 -3.84e-01 3.66e-01
REACTOME SPHINGOLIPID METABOLISM 84 4.61e-02 -1.26e-01 3.66e-01
REACTOME REGULATION OF SIGNALING BY CBL 22 4.61e-02 -2.46e-01 3.66e-01
REACTOME ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS 10 4.65e-02 -3.64e-01 3.66e-01
REACTOME SUMOYLATION OF RNA BINDING PROTEINS 47 4.70e-02 -1.67e-01 3.66e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY 19 4.72e-02 2.63e-01 3.66e-01
REACTOME VESICLE MEDIATED TRANSPORT 642 4.72e-02 -4.59e-02 3.66e-01
REACTOME NOD1 2 SIGNALING PATHWAY 33 4.73e-02 -2.00e-01 3.66e-01
REACTOME BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA 17 4.73e-02 -2.78e-01 3.66e-01
REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS 83 4.75e-02 -1.26e-01 3.66e-01
REACTOME FORMATION OF APOPTOSOME 10 4.77e-02 -3.62e-01 3.66e-01
REACTOME CHYLOMICRON REMODELING 10 4.77e-02 3.62e-01 3.66e-01
REACTOME TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS 55 4.79e-02 -1.54e-01 3.66e-01
REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 44 4.83e-02 -1.72e-01 3.66e-01
REACTOME SIGNALING BY RECEPTOR TYROSINE KINASES 507 4.84e-02 -5.12e-02 3.66e-01
REACTOME PRE NOTCH EXPRESSION AND PROCESSING 112 4.86e-02 -1.08e-01 3.66e-01
REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX 15 4.87e-02 -2.94e-01 3.66e-01
REACTOME NS1 MEDIATED EFFECTS ON HOST PATHWAYS 41 4.88e-02 -1.78e-01 3.66e-01
REACTOME SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS 74 4.93e-02 -1.32e-01 3.66e-01
REACTOME FC EPSILON RECEPTOR FCERI SIGNALING 127 4.93e-02 -1.01e-01 3.66e-01
REACTOME REGULATION OF IFNG SIGNALING 14 5.15e-02 -3.01e-01 3.79e-01
REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF 53 5.15e-02 -1.55e-01 3.79e-01
REACTOME SIGNALING BY FGFR2 72 5.18e-02 -1.33e-01 3.79e-01
REACTOME CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND 16 5.20e-02 -2.81e-01 3.79e-01
REACTOME DOWNSTREAM SIGNAL TRANSDUCTION 29 5.22e-02 -2.08e-01 3.79e-01
REACTOME ALPHA DEFENSINS 6 5.37e-02 4.55e-01 3.88e-01
REACTOME TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY 30 5.40e-02 -2.03e-01 3.89e-01
REACTOME TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA 17 5.48e-02 -2.69e-01 3.92e-01
REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION 20 5.51e-02 2.48e-01 3.92e-01
REACTOME MISCELLANEOUS SUBSTRATES 12 5.51e-02 3.20e-01 3.92e-01
REACTOME HOMOLOGY DIRECTED REPAIR 132 5.57e-02 -9.64e-02 3.94e-01
REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS 16 5.64e-02 2.76e-01 3.97e-01
REACTOME GENE SILENCING BY RNA 133 5.74e-02 -9.54e-02 4.01e-01
REACTOME INTRAFLAGELLAR TRANSPORT 50 5.76e-02 -1.55e-01 4.01e-01
REACTOME SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS 12 5.77e-02 -3.16e-01 4.01e-01
REACTOME REGULATION OF TP53 ACTIVITY 156 5.80e-02 -8.79e-02 4.02e-01
REACTOME SIGNALING BY ALK IN CANCER 53 5.84e-02 -1.50e-01 4.03e-01
REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION 183 5.89e-02 -8.10e-02 4.03e-01
REACTOME COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM 21 5.90e-02 2.38e-01 4.03e-01
REACTOME DNA REPAIR 321 5.94e-02 -6.12e-02 4.03e-01
REACTOME HDR THROUGH SINGLE STRAND ANNEALING SSA 37 5.95e-02 -1.79e-01 4.03e-01
REACTOME HDL CLEARANCE 5 5.99e-02 4.86e-01 4.05e-01
REACTOME ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS 24 6.03e-02 -2.22e-01 4.06e-01
REACTOME INTERFERON ALPHA BETA SIGNALING 70 6.06e-02 -1.30e-01 4.06e-01
REACTOME SIGNALING BY WNT 318 6.10e-02 -6.11e-02 4.07e-01
REACTOME SIGNALING BY ALK 26 6.12e-02 -2.12e-01 4.07e-01
REACTOME UBIQUINOL BIOSYNTHESIS 8 6.16e-02 3.82e-01 4.08e-01
REACTOME MYD88 INDEPENDENT TLR4 CASCADE 103 6.21e-02 -1.06e-01 4.09e-01
REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ 6 6.24e-02 -4.39e-01 4.10e-01
REACTOME PARASITE INFECTION 57 6.29e-02 -1.42e-01 4.10e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE 74 6.30e-02 1.25e-01 4.10e-01
REACTOME DRUG ADME 103 6.33e-02 1.06e-01 4.11e-01
REACTOME INACTIVATION OF CSF3 G CSF SIGNALING 25 6.42e-02 -2.14e-01 4.15e-01
REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER 49 6.45e-02 -1.53e-01 4.15e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE 20 6.47e-02 2.39e-01 4.15e-01
REACTOME METABOLISM OF VITAMINS AND COFACTORS 185 6.51e-02 7.86e-02 4.15e-01
REACTOME MISMATCH REPAIR 15 6.53e-02 -2.75e-01 4.15e-01
REACTOME SUMOYLATION OF SUMOYLATION PROTEINS 35 6.56e-02 -1.80e-01 4.16e-01
REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL 129 6.64e-02 9.36e-02 4.18e-01
REACTOME RHO GTPASE CYCLE 423 6.65e-02 -5.20e-02 4.18e-01
REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING 45 6.70e-02 -1.58e-01 4.19e-01
REACTOME G0 AND EARLY G1 27 6.71e-02 -2.04e-01 4.19e-01
REACTOME TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT 18 6.79e-02 -2.49e-01 4.23e-01
REACTOME METABOLISM OF LIPIDS 709 6.85e-02 -4.02e-02 4.24e-01
REACTOME TP53 REGULATES METABOLIC GENES 81 6.88e-02 -1.17e-01 4.25e-01
REACTOME ASSEMBLY OF THE HIV VIRION 16 6.98e-02 -2.62e-01 4.28e-01
REACTOME PTK6 REGULATES CELL CYCLE 6 7.04e-02 -4.27e-01 4.28e-01
REACTOME SIGNALING BY FGFR IN DISEASE 62 7.04e-02 -1.33e-01 4.28e-01
REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP 104 7.04e-02 -1.03e-01 4.28e-01
REACTOME TLR3 MEDIATED TICAM1 DEPENDENT PROGRAMMED CELL DEATH 6 7.15e-02 -4.25e-01 4.33e-01
REACTOME VLDL ASSEMBLY 5 7.22e-02 4.64e-01 4.34e-01
REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING 16 7.22e-02 -2.60e-01 4.34e-01
REACTOME INTERACTION BETWEEN L1 AND ANKYRINS 30 7.28e-02 1.89e-01 4.34e-01
REACTOME KSRP KHSRP BINDS AND DESTABILIZES MRNA 17 7.33e-02 -2.51e-01 4.34e-01
REACTOME METABOLISM OF RNA 675 7.39e-02 -4.03e-02 4.34e-01
REACTOME ERYTHROPOIETIN ACTIVATES STAT5 7 7.43e-02 -3.90e-01 4.34e-01
REACTOME TRANSLESION SYNTHESIS BY POLH 19 7.44e-02 -2.36e-01 4.34e-01
REACTOME SIGNALING BY EGFR 49 7.44e-02 -1.47e-01 4.34e-01
REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION 10 7.45e-02 -3.26e-01 4.34e-01
REACTOME EPHA MEDIATED GROWTH CONE COLLAPSE 29 7.45e-02 -1.91e-01 4.34e-01
REACTOME SIGNALING BY TGFB FAMILY MEMBERS 119 7.48e-02 -9.45e-02 4.34e-01
REACTOME SYNTHESIS OF GDP MANNOSE 5 7.51e-02 -4.60e-01 4.34e-01
REACTOME NEUROTRANSMITTER RELEASE CYCLE 48 7.52e-02 -1.48e-01 4.34e-01
REACTOME CIRCADIAN CLOCK 68 7.53e-02 -1.25e-01 4.34e-01
REACTOME TOLL LIKE RECEPTOR 9 TLR9 CASCADE 100 7.61e-02 -1.03e-01 4.36e-01
REACTOME PROLONGED ERK ACTIVATION EVENTS 14 7.63e-02 -2.74e-01 4.36e-01
REACTOME ATTACHMENT OF GPI ANCHOR TO UPAR 7 7.70e-02 -3.86e-01 4.39e-01
REACTOME GOLGI TO ER RETROGRADE TRANSPORT 132 7.78e-02 -8.89e-02 4.42e-01
REACTOME SIGNALING BY SCF KIT 42 7.83e-02 -1.57e-01 4.43e-01
REACTOME APEX1 INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY 7 7.88e-02 3.84e-01 4.44e-01
REACTOME HYALURONAN METABOLISM 17 7.90e-02 2.46e-01 4.44e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION 29 7.93e-02 -1.88e-01 4.44e-01
REACTOME ER TO GOLGI ANTEROGRADE TRANSPORT 152 8.23e-02 -8.17e-02 4.58e-01
REACTOME ONCOGENE INDUCED SENESCENCE 35 8.24e-02 -1.70e-01 4.58e-01
REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS 83 8.28e-02 -1.10e-01 4.58e-01
REACTOME RIBAVIRIN ADME 11 8.29e-02 -3.02e-01 4.58e-01
REACTOME ACTIVATION OF NIMA KINASES NEK9 NEK6 NEK7 7 8.47e-02 3.76e-01 4.66e-01
REACTOME SYNTHESIS OF PC 27 8.48e-02 -1.92e-01 4.66e-01
REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN 32 8.64e-02 -1.75e-01 4.73e-01
REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON 17 8.69e-02 -2.40e-01 4.74e-01
REACTOME TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX 10 8.71e-02 -3.12e-01 4.74e-01
REACTOME TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER 76 8.89e-02 -1.13e-01 4.82e-01
REACTOME GLUCAGON TYPE LIGAND RECEPTORS 32 9.06e-02 1.73e-01 4.88e-01
REACTOME TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA 36 9.07e-02 -1.63e-01 4.88e-01
REACTOME RNA POLYMERASE II TRANSCRIPTION 1336 9.10e-02 -2.76e-02 4.88e-01
REACTOME REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE 81 9.22e-02 -1.08e-01 4.93e-01
REACTOME RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION 6 9.29e-02 -3.96e-01 4.95e-01
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA 263 9.31e-02 -6.01e-02 4.95e-01
REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS 23 9.39e-02 -2.02e-01 4.95e-01
REACTOME CHYLOMICRON ASSEMBLY 10 9.39e-02 3.06e-01 4.95e-01
REACTOME GERM LAYER FORMATION AT GASTRULATION 17 9.45e-02 -2.34e-01 4.95e-01
REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM 50 9.46e-02 -1.37e-01 4.95e-01
REACTOME SIGNALING BY FLT3 FUSION PROTEINS 19 9.50e-02 -2.21e-01 4.95e-01
REACTOME RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION 6 9.51e-02 -3.93e-01 4.95e-01
REACTOME DISEASES ASSOCIATED WITH SURFACTANT METABOLISM 9 9.56e-02 3.21e-01 4.95e-01
REACTOME CONJUGATION OF BENZOATE WITH GLYCINE 6 9.57e-02 3.93e-01 4.95e-01
REACTOME RORA ACTIVATES GENE EXPRESSION 17 9.59e-02 -2.33e-01 4.95e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K 12 9.63e-02 -2.77e-01 4.95e-01
REACTOME ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING 9 9.69e-02 -3.20e-01 4.97e-01
REACTOME SYNTHESIS OF PI 5 9.73e-02 -4.28e-01 4.97e-01
REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION 160 9.77e-02 -7.59e-02 4.97e-01
REACTOME SIGNALING BY FGFR2 IN DISEASE 42 9.78e-02 -1.48e-01 4.97e-01
REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS 53 9.85e-02 -1.31e-01 4.99e-01
REACTOME PENTOSE PHOSPHATE PATHWAY 12 9.90e-02 -2.75e-01 5.00e-01
REACTOME DEADENYLATION DEPENDENT MRNA DECAY 56 1.00e-01 -1.27e-01 5.05e-01
REACTOME TRANSLESION SYNTHESIS BY POLK 17 1.01e-01 -2.30e-01 5.09e-01
REACTOME LEISHMANIA INFECTION 156 1.02e-01 -7.58e-02 5.11e-01
REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE 52 1.03e-01 -1.31e-01 5.14e-01
REACTOME VIRAL MESSENGER RNA SYNTHESIS 44 1.03e-01 -1.42e-01 5.14e-01
REACTOME SYNTHESIS OF PE 13 1.04e-01 -2.61e-01 5.15e-01
REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM 23 1.05e-01 1.96e-01 5.17e-01
REACTOME FLT3 SIGNALING IN DISEASE 28 1.05e-01 -1.77e-01 5.17e-01
REACTOME NEURONAL SYSTEM 388 1.06e-01 -4.79e-02 5.17e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING 5 1.06e-01 -4.18e-01 5.17e-01
REACTOME DEFECTIVE F9 ACTIVATION 5 1.06e-01 -4.17e-01 5.17e-01
REACTOME DNA REPLICATION INITIATION 7 1.06e-01 3.53e-01 5.17e-01
REACTOME PARACETAMOL ADME 26 1.09e-01 1.82e-01 5.29e-01
REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC 28 1.09e-01 -1.75e-01 5.29e-01
REACTOME DEFECTS IN VITAMIN AND COFACTOR METABOLISM 21 1.09e-01 2.02e-01 5.29e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS 15 1.10e-01 -2.38e-01 5.29e-01
REACTOME FATTY ACIDS 15 1.11e-01 2.37e-01 5.34e-01
REACTOME CD28 CO STIMULATION 32 1.12e-01 -1.62e-01 5.35e-01
REACTOME RECYCLING OF BILE ACIDS AND SALTS 18 1.12e-01 2.16e-01 5.35e-01
REACTOME ORGANIC ANION TRANSPORTERS 10 1.13e-01 -2.90e-01 5.35e-01
REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION 26 1.13e-01 -1.80e-01 5.35e-01
REACTOME TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE 39 1.13e-01 -1.46e-01 5.35e-01
REACTOME SIGNALING BY NUCLEAR RECEPTORS 283 1.13e-01 -5.47e-02 5.35e-01
REACTOME DNA DOUBLE STRAND BREAK REPAIR 162 1.14e-01 -7.20e-02 5.35e-01
REACTOME GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION 30 1.14e-01 1.67e-01 5.35e-01
REACTOME BINDING OF TCF LEF CTNNB1 TO TARGET GENE PROMOTERS 8 1.15e-01 -3.22e-01 5.38e-01
REACTOME EPH EPHRIN SIGNALING 90 1.16e-01 -9.60e-02 5.38e-01
REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION 19 1.16e-01 -2.08e-01 5.38e-01
REACTOME GLUCURONIDATION 23 1.16e-01 1.89e-01 5.38e-01
REACTOME SMAC XIAP REGULATED APOPTOTIC RESPONSE 7 1.17e-01 -3.43e-01 5.38e-01
REACTOME ACTIVATION OF CASPASES THROUGH APOPTOSOME MEDIATED CLEAVAGE 5 1.17e-01 -4.05e-01 5.38e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX 91 1.17e-01 -9.50e-02 5.38e-01
REACTOME ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS 17 1.17e-01 -2.19e-01 5.38e-01
REACTOME TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7 12 1.18e-01 -2.61e-01 5.39e-01
REACTOME INTERLEUKIN 37 SIGNALING 20 1.18e-01 -2.02e-01 5.39e-01
REACTOME TNFR1 INDUCED PROAPOPTOTIC SIGNALING 23 1.19e-01 -1.88e-01 5.39e-01
REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION 15 1.19e-01 -2.33e-01 5.39e-01
REACTOME INTERLEUKIN 6 SIGNALING 11 1.19e-01 -2.71e-01 5.39e-01
REACTOME CD209 DC SIGN SIGNALING 20 1.20e-01 -2.01e-01 5.40e-01
REACTOME EICOSANOIDS 12 1.20e-01 2.59e-01 5.40e-01
REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE 71 1.21e-01 -1.07e-01 5.40e-01
REACTOME DEFECTIVE CSF2RB CAUSES SMDP5 7 1.21e-01 3.39e-01 5.40e-01
REACTOME CA2 ACTIVATED K CHANNELS 9 1.21e-01 2.98e-01 5.40e-01
REACTOME PEPTIDE HORMONE BIOSYNTHESIS 13 1.22e-01 2.48e-01 5.41e-01
REACTOME METABOLISM OF COFACTORS 19 1.22e-01 2.05e-01 5.41e-01
REACTOME FORMATION OF AXIAL MESODERM 14 1.22e-01 -2.39e-01 5.41e-01
REACTOME RAB REGULATION OF TRAFFICKING 110 1.23e-01 -8.51e-02 5.43e-01
REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA 11 1.24e-01 2.68e-01 5.43e-01
REACTOME RHOD GTPASE CYCLE 49 1.24e-01 -1.27e-01 5.43e-01
REACTOME NUCLEOTIDE SALVAGE 21 1.25e-01 -1.94e-01 5.43e-01
REACTOME DISEASES OF MITOTIC CELL CYCLE 37 1.25e-01 -1.46e-01 5.43e-01
REACTOME KERATINIZATION 210 1.25e-01 6.14e-02 5.43e-01
REACTOME BIOSYNTHESIS OF MARESINS 8 1.25e-01 3.13e-01 5.43e-01
REACTOME INTEGRATION OF PROVIRUS 9 1.27e-01 -2.94e-01 5.49e-01
REACTOME SOS MEDIATED SIGNALLING 7 1.27e-01 -3.33e-01 5.51e-01
REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY 5 1.29e-01 -3.92e-01 5.56e-01
REACTOME MITOCHONDRIAL CALCIUM ION TRANSPORT 23 1.31e-01 -1.82e-01 5.61e-01
REACTOME MEIOSIS 110 1.31e-01 -8.33e-02 5.61e-01
REACTOME SIGNALING BY PDGF 57 1.31e-01 -1.15e-01 5.61e-01
REACTOME APOPTOTIC EXECUTION PHASE 49 1.32e-01 -1.24e-01 5.61e-01
REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS 16 1.32e-01 -2.17e-01 5.61e-01
REACTOME PLATELET AGGREGATION PLUG FORMATION 39 1.32e-01 -1.39e-01 5.61e-01
REACTOME SIGNALING BY CSF3 G CSF 30 1.32e-01 -1.59e-01 5.61e-01
REACTOME TBC RABGAPS 40 1.33e-01 -1.37e-01 5.61e-01
REACTOME RUNX2 REGULATES CHONDROCYTE MATURATION 5 1.34e-01 -3.87e-01 5.61e-01
REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN 37 1.34e-01 -1.42e-01 5.61e-01
REACTOME MATURATION OF SARS COV 2 SPIKE PROTEIN 35 1.35e-01 -1.46e-01 5.61e-01
REACTOME SIGNALING BY FGFR 85 1.35e-01 -9.39e-02 5.61e-01
REACTOME COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC 98 1.35e-01 -8.75e-02 5.61e-01
REACTOME INTRINSIC PATHWAY FOR APOPTOSIS 54 1.36e-01 -1.17e-01 5.63e-01
REACTOME RAP1 SIGNALLING 16 1.36e-01 -2.15e-01 5.63e-01
REACTOME ARMS MEDIATED ACTIVATION 7 1.37e-01 -3.25e-01 5.63e-01
REACTOME NECTIN NECL TRANS HETERODIMERIZATION 7 1.37e-01 3.25e-01 5.63e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS 9 1.37e-01 2.86e-01 5.63e-01
REACTOME EGFR DOWNREGULATION 30 1.37e-01 -1.57e-01 5.63e-01
REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES 91 1.38e-01 -9.01e-02 5.63e-01
REACTOME TOLL LIKE RECEPTOR CASCADES 158 1.38e-01 -6.83e-02 5.65e-01
REACTOME XENOBIOTICS 22 1.39e-01 1.82e-01 5.65e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL 14 1.39e-01 2.28e-01 5.65e-01
REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES 22 1.40e-01 -1.82e-01 5.68e-01
REACTOME CHOLESTEROL BIOSYNTHESIS 25 1.40e-01 -1.70e-01 5.68e-01
REACTOME COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC 52 1.42e-01 -1.18e-01 5.74e-01
REACTOME SODIUM PROTON EXCHANGERS 7 1.43e-01 3.20e-01 5.74e-01
REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION 31 1.43e-01 -1.52e-01 5.75e-01
REACTOME GLYCOSPHINGOLIPID METABOLISM 39 1.44e-01 -1.35e-01 5.76e-01
REACTOME FGFR2 ALTERNATIVE SPLICING 27 1.45e-01 -1.62e-01 5.76e-01
REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION 84 1.45e-01 -9.20e-02 5.76e-01
REACTOME TRANS GOLGI NETWORK VESICLE BUDDING 67 1.45e-01 -1.03e-01 5.76e-01
REACTOME MITOTIC PROPHASE 134 1.45e-01 -7.29e-02 5.76e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS 7 1.46e-01 -3.18e-01 5.76e-01
REACTOME GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER 25 1.46e-01 -1.68e-01 5.76e-01
REACTOME EPITHELIAL MESENCHYMAL TRANSITION EMT DURING GASTRULATION 7 1.46e-01 -3.17e-01 5.76e-01
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION 138 1.48e-01 -7.13e-02 5.82e-01
REACTOME DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE 76 1.49e-01 -9.58e-02 5.83e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA 27 1.50e-01 -1.60e-01 5.84e-01
REACTOME KEAP1 NFE2L2 PATHWAY 104 1.50e-01 -8.17e-02 5.84e-01
REACTOME SCAVENGING OF HEME FROM PLASMA 13 1.50e-01 2.31e-01 5.84e-01
REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM 78 1.50e-01 -9.42e-02 5.84e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS 7 1.51e-01 -3.13e-01 5.85e-01
REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING 26 1.52e-01 -1.62e-01 5.85e-01
REACTOME SELECTIVE AUTOPHAGY 79 1.52e-01 -9.33e-02 5.85e-01
REACTOME DUAL INCISION IN GG NER 39 1.52e-01 -1.33e-01 5.85e-01
REACTOME ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS 87 1.54e-01 -8.85e-02 5.90e-01
REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 100 1.54e-01 -8.25e-02 5.90e-01
REACTOME MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS 17 1.55e-01 -1.99e-01 5.91e-01
REACTOME FLT3 SIGNALING 38 1.56e-01 -1.33e-01 5.93e-01
REACTOME DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B 7 1.56e-01 -3.10e-01 5.93e-01
REACTOME AGGREPHAGY 42 1.57e-01 -1.26e-01 5.95e-01
REACTOME SIGNALING BY FGFR3 39 1.58e-01 -1.31e-01 5.97e-01
REACTOME ATTACHMENT AND ENTRY 16 1.59e-01 -2.03e-01 6.01e-01
REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION 12 1.61e-01 -2.34e-01 6.05e-01
REACTOME DNA DAMAGE BYPASS 47 1.61e-01 -1.18e-01 6.05e-01
REACTOME SUMO IS PROTEOLYTICALLY PROCESSED 6 1.62e-01 3.30e-01 6.07e-01
REACTOME PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR 21 1.62e-01 -1.76e-01 6.07e-01
REACTOME MYOCLONIC EPILEPSY OF LAFORA 9 1.63e-01 -2.69e-01 6.07e-01
REACTOME PHASE 3 RAPID REPOLARISATION 8 1.63e-01 -2.85e-01 6.07e-01
REACTOME TERMINATION OF TRANSLESION DNA SYNTHESIS 32 1.64e-01 -1.42e-01 6.07e-01
REACTOME REGULATION OF NF KAPPA B SIGNALING 17 1.64e-01 -1.95e-01 6.07e-01
REACTOME JOSEPHIN DOMAIN DUBS 11 1.64e-01 -2.42e-01 6.07e-01
REACTOME SARS COV 2 INFECTION 281 1.65e-01 -4.82e-02 6.07e-01
REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS 299 1.66e-01 -4.66e-02 6.10e-01
REACTOME SIGNALING BY PDGFR IN DISEASE 20 1.66e-01 -1.79e-01 6.10e-01
REACTOME REGULATION OF INSULIN SECRETION 77 1.67e-01 9.11e-02 6.11e-01
REACTOME RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK 47 1.67e-01 -1.16e-01 6.11e-01
REACTOME STAT3 NUCLEAR EVENTS DOWNSTREAM OF ALK SIGNALING 9 1.68e-01 -2.65e-01 6.13e-01
REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS 46 1.69e-01 -1.17e-01 6.14e-01
REACTOME MITOTIC G2 G2 M PHASES 194 1.70e-01 -5.72e-02 6.14e-01
REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION 74 1.70e-01 -9.23e-02 6.14e-01
REACTOME HIV ELONGATION ARREST AND RECOVERY 33 1.70e-01 -1.38e-01 6.14e-01
REACTOME DEFECTS IN COBALAMIN B12 METABOLISM 13 1.73e-01 2.18e-01 6.19e-01
REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS 45 1.73e-01 -1.17e-01 6.19e-01
REACTOME RELEASE OF HH NP FROM THE SECRETING CELL 8 1.73e-01 -2.78e-01 6.19e-01
REACTOME MOLYBDENUM COFACTOR BIOSYNTHESIS 6 1.74e-01 -3.21e-01 6.19e-01
REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS 101 1.74e-01 7.83e-02 6.19e-01
REACTOME NEDDYLATION 235 1.74e-01 -5.15e-02 6.19e-01
REACTOME RESPIRATORY ELECTRON TRANSPORT 90 1.74e-01 -8.29e-02 6.19e-01
REACTOME ETHANOL OXIDATION 12 1.75e-01 -2.26e-01 6.19e-01
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES 255 1.75e-01 -4.93e-02 6.19e-01
REACTOME MODULATION BY MTB OF HOST IMMUNE SYSTEM 6 1.75e-01 -3.19e-01 6.19e-01
REACTOME TCR SIGNALING 113 1.76e-01 -7.37e-02 6.19e-01
REACTOME POTENTIAL THERAPEUTICS FOR SARS 92 1.76e-01 -8.17e-02 6.19e-01
REACTOME SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX 15 1.76e-01 -2.02e-01 6.21e-01
REACTOME FIBRONECTIN MATRIX FORMATION 6 1.77e-01 3.18e-01 6.21e-01
REACTOME PHASE 0 RAPID DEPOLARISATION 31 1.79e-01 1.39e-01 6.27e-01
REACTOME RHO GTPASES ACTIVATE WASPS AND WAVES 34 1.80e-01 -1.33e-01 6.27e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES 33 1.80e-01 -1.35e-01 6.27e-01
REACTOME SIGNALING BY NOTCH 234 1.81e-01 -5.07e-02 6.29e-01
REACTOME SCAVENGING BY CLASS A RECEPTORS 19 1.81e-01 1.77e-01 6.29e-01
REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 98 1.82e-01 -7.79e-02 6.31e-01
REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES 78 1.83e-01 -8.73e-02 6.31e-01
REACTOME GPVI MEDIATED ACTIVATION CASCADE 35 1.85e-01 -1.30e-01 6.36e-01
REACTOME METABOLISM OF FOLATE AND PTERINES 17 1.85e-01 -1.86e-01 6.36e-01
REACTOME RSK ACTIVATION 5 1.86e-01 -3.41e-01 6.36e-01
REACTOME INTERLEUKIN 23 SIGNALING 9 1.86e-01 -2.55e-01 6.36e-01
REACTOME PI METABOLISM 79 1.87e-01 -8.59e-02 6.36e-01
REACTOME PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING 5 1.87e-01 -3.41e-01 6.36e-01
REACTOME RHO GTPASES ACTIVATE PKNS 86 1.87e-01 -8.24e-02 6.36e-01
REACTOME PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING 11 1.88e-01 2.29e-01 6.36e-01
REACTOME RUNX3 REGULATES WNT SIGNALING 8 1.88e-01 -2.69e-01 6.36e-01
REACTOME L1CAM INTERACTIONS 112 1.88e-01 7.20e-02 6.36e-01
REACTOME REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION 9 1.88e-01 -2.53e-01 6.36e-01
REACTOME SYNTHESIS OF PA 38 1.89e-01 -1.23e-01 6.36e-01
REACTOME INTERLEUKIN 17 SIGNALING 66 1.90e-01 -9.34e-02 6.36e-01
REACTOME GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION 14 1.90e-01 -2.02e-01 6.36e-01
REACTOME EPH EPHRIN MEDIATED REPULSION OF CELLS 50 1.90e-01 -1.07e-01 6.36e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS 121 1.90e-01 -6.89e-02 6.37e-01
REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS 55 1.91e-01 1.02e-01 6.38e-01
REACTOME RUNX3 REGULATES YAP1 MEDIATED TRANSCRIPTION 8 1.92e-01 -2.67e-01 6.38e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS 12 1.92e-01 2.17e-01 6.38e-01
REACTOME PKMTS METHYLATE HISTONE LYSINES 64 1.94e-01 -9.38e-02 6.43e-01
REACTOME PRC2 METHYLATES HISTONES AND DNA 65 1.94e-01 -9.31e-02 6.43e-01
REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE 109 1.95e-01 -7.19e-02 6.44e-01
REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION 13 1.97e-01 -2.07e-01 6.48e-01
REACTOME SCAVENGING BY CLASS B RECEPTORS 6 1.97e-01 3.04e-01 6.48e-01
REACTOME ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY 5 1.97e-01 -3.33e-01 6.48e-01
REACTOME INFLUENZA INFECTION 149 1.98e-01 -6.11e-02 6.48e-01
REACTOME PROTON COUPLED MONOCARBOXYLATE TRANSPORT 6 1.99e-01 -3.03e-01 6.48e-01
REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE 9 1.99e-01 2.47e-01 6.48e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR2 29 1.99e-01 -1.38e-01 6.48e-01
REACTOME CRISTAE FORMATION 27 2.02e-01 -1.42e-01 6.56e-01
REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE 15 2.02e-01 -1.90e-01 6.56e-01
REACTOME ACYL CHAIN REMODELING OF DAG AND TAG 5 2.03e-01 -3.29e-01 6.56e-01
REACTOME SUMOYLATION OF TRANSCRIPTION FACTORS 20 2.04e-01 -1.64e-01 6.57e-01
REACTOME LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME 11 2.04e-01 -2.21e-01 6.57e-01
REACTOME RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION 8 2.04e-01 -2.59e-01 6.57e-01
REACTOME HDL REMODELING 10 2.05e-01 2.32e-01 6.57e-01
REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS 43 2.06e-01 -1.11e-01 6.60e-01
REACTOME TRP CHANNELS 27 2.06e-01 -1.41e-01 6.60e-01
REACTOME TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS 43 2.07e-01 -1.11e-01 6.61e-01
REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE 63 2.07e-01 9.18e-02 6.61e-01
REACTOME MATURATION OF SARS COV 1 SPIKE PROTEIN 5 2.08e-01 -3.25e-01 6.61e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION 102 2.09e-01 -7.20e-02 6.61e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR3 24 2.09e-01 -1.48e-01 6.61e-01
REACTOME INTERLEUKIN 2 SIGNALING 11 2.10e-01 -2.18e-01 6.61e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING 25 2.10e-01 -1.45e-01 6.61e-01
REACTOME RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION 22 2.10e-01 -1.54e-01 6.61e-01
REACTOME MITOTIC METAPHASE AND ANAPHASE 228 2.11e-01 -4.81e-02 6.61e-01
REACTOME LYSOSOME VESICLE BIOGENESIS 33 2.11e-01 -1.26e-01 6.61e-01
REACTOME METALLOPROTEASE DUBS 36 2.11e-01 -1.20e-01 6.61e-01
REACTOME INTEGRIN SIGNALING 27 2.12e-01 -1.39e-01 6.61e-01
REACTOME FCGR ACTIVATION 11 2.12e-01 -2.17e-01 6.61e-01
REACTOME MEIOTIC RECOMBINATION 80 2.13e-01 -8.06e-02 6.61e-01
REACTOME PURINE SALVAGE 12 2.13e-01 -2.07e-01 6.61e-01
REACTOME HEDGEHOG LIGAND BIOGENESIS 64 2.14e-01 -8.99e-02 6.61e-01
REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS 51 2.14e-01 -1.01e-01 6.61e-01
REACTOME MAPK6 MAPK4 SIGNALING 91 2.15e-01 -7.52e-02 6.61e-01
REACTOME BETA CATENIN INDEPENDENT WNT SIGNALING 145 2.15e-01 -5.96e-02 6.61e-01
REACTOME SIGNALING BY FGFR4 40 2.16e-01 -1.13e-01 6.61e-01
REACTOME MAP2K AND MAPK ACTIVATION 38 2.16e-01 -1.16e-01 6.61e-01
REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS 5 2.16e-01 3.19e-01 6.61e-01
REACTOME NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 24 2.17e-01 -1.46e-01 6.61e-01
REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES 29 2.17e-01 -1.33e-01 6.61e-01
REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4 33 2.17e-01 -1.24e-01 6.61e-01
REACTOME G1 S SPECIFIC TRANSCRIPTION 28 2.17e-01 -1.35e-01 6.61e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL 14 2.17e-01 -1.90e-01 6.61e-01
REACTOME SIGNALING BY FGFR1 49 2.19e-01 -1.01e-01 6.63e-01
REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN 19 2.20e-01 -1.63e-01 6.63e-01
REACTOME UNFOLDED PROTEIN RESPONSE UPR 88 2.20e-01 7.57e-02 6.63e-01
REACTOME NERVOUS SYSTEM DEVELOPMENT 552 2.20e-01 -3.05e-02 6.63e-01
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION 250 2.20e-01 -4.50e-02 6.63e-01
REACTOME THE PHOTOTRANSDUCTION CASCADE 32 2.21e-01 1.25e-01 6.64e-01
REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS 11 2.24e-01 2.12e-01 6.71e-01
REACTOME BETA OXIDATION OF PRISTANOYL COA 9 2.24e-01 2.34e-01 6.71e-01
REACTOME SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA PHE 6 2.25e-01 -2.86e-01 6.71e-01
REACTOME SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS 43 2.25e-01 -1.07e-01 6.71e-01
REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE 63 2.25e-01 -8.84e-02 6.71e-01
REACTOME SIGNALING BY ERBB2 50 2.26e-01 -9.90e-02 6.71e-01
REACTOME RECYCLING OF EIF2 GDP 7 2.26e-01 2.64e-01 6.71e-01
REACTOME GROWTH HORMONE RECEPTOR SIGNALING 24 2.27e-01 -1.43e-01 6.71e-01
REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS 18 2.27e-01 -1.65e-01 6.71e-01
REACTOME TELOMERE C STRAND LAGGING STRAND SYNTHESIS 33 2.28e-01 -1.21e-01 6.73e-01
REACTOME DNA REPLICATION 178 2.28e-01 -5.24e-02 6.73e-01
REACTOME MET PROMOTES CELL MOTILITY 41 2.29e-01 1.09e-01 6.74e-01
REACTOME CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA 63 2.30e-01 -8.75e-02 6.75e-01
REACTOME RAS PROCESSING 22 2.30e-01 -1.48e-01 6.75e-01
REACTOME GLUCOSE METABOLISM 90 2.31e-01 -7.30e-02 6.77e-01
REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS 86 2.32e-01 -7.46e-02 6.77e-01
REACTOME MRNA SPLICING MINOR PATHWAY 49 2.32e-01 9.87e-02 6.77e-01
REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM 45 2.33e-01 -1.03e-01 6.77e-01
REACTOME RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX 29 2.33e-01 -1.28e-01 6.77e-01
REACTOME VEGFR2 MEDIATED CELL PROLIFERATION 19 2.33e-01 -1.58e-01 6.77e-01
REACTOME RMTS METHYLATE HISTONE ARGININES 72 2.35e-01 -8.10e-02 6.79e-01
REACTOME PROCESSING OF DNA DOUBLE STRAND BREAK ENDS 93 2.35e-01 -7.12e-02 6.79e-01
REACTOME MRNA EDITING 10 2.36e-01 2.17e-01 6.79e-01
REACTOME SIGNALING BY THE B CELL RECEPTOR BCR 106 2.36e-01 -6.66e-02 6.79e-01
REACTOME INTERLEUKIN 15 SIGNALING 13 2.37e-01 -1.90e-01 6.80e-01
REACTOME PROTEIN FOLDING 96 2.38e-01 -6.98e-02 6.82e-01
REACTOME SUMOYLATION OF DNA METHYLATION PROTEINS 16 2.39e-01 -1.70e-01 6.84e-01
REACTOME REGULATION OF MECP2 EXPRESSION AND ACTIVITY 30 2.40e-01 -1.24e-01 6.85e-01
REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX 36 2.41e-01 1.13e-01 6.85e-01
REACTOME SIGNALING BY LEPTIN 11 2.43e-01 -2.03e-01 6.85e-01
REACTOME ATORVASTATIN ADME 9 2.43e-01 2.25e-01 6.85e-01
REACTOME NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 19 2.43e-01 -1.55e-01 6.85e-01
REACTOME TRANSCRIPTION OF THE HIV GENOME 66 2.44e-01 -8.30e-02 6.85e-01
REACTOME CGMP EFFECTS 16 2.44e-01 1.68e-01 6.85e-01
REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE 22 2.44e-01 1.43e-01 6.85e-01
REACTOME BASE EXCISION REPAIR 87 2.45e-01 -7.22e-02 6.85e-01
REACTOME INSULIN PROCESSING 24 2.45e-01 -1.37e-01 6.85e-01
REACTOME FGFRL1 MODULATION OF FGFR1 SIGNALING 13 2.45e-01 -1.86e-01 6.85e-01
REACTOME DISEASES OF BASE EXCISION REPAIR 5 2.45e-01 -3.00e-01 6.85e-01
REACTOME ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS 41 2.45e-01 -1.05e-01 6.85e-01
REACTOME TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS 29 2.46e-01 -1.24e-01 6.85e-01
REACTOME LATE ENDOSOMAL MICROAUTOPHAGY 33 2.46e-01 -1.17e-01 6.85e-01
REACTOME SIGNALING BY FLT3 ITD AND TKD MUTANTS 16 2.46e-01 -1.67e-01 6.85e-01
REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION 20 2.46e-01 -1.50e-01 6.85e-01
REACTOME CTLA4 INHIBITORY SIGNALING 21 2.47e-01 1.46e-01 6.85e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES 49 2.47e-01 -9.56e-02 6.85e-01
REACTOME CARGO CONCENTRATION IN THE ER 32 2.48e-01 1.18e-01 6.87e-01
REACTOME PYRIMIDINE SALVAGE 10 2.49e-01 -2.11e-01 6.87e-01
REACTOME TRANSCRIPTIONAL REGULATION BY VENTX 41 2.49e-01 -1.04e-01 6.87e-01
REACTOME RUNX3 REGULATES NOTCH SIGNALING 13 2.49e-01 -1.85e-01 6.87e-01
REACTOME OTHER INTERLEUKIN SIGNALING 24 2.51e-01 -1.35e-01 6.89e-01
REACTOME MRNA EDITING C TO U CONVERSION 8 2.51e-01 2.34e-01 6.89e-01
REACTOME HIV TRANSCRIPTION ELONGATION 42 2.51e-01 -1.02e-01 6.89e-01
REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS 118 2.52e-01 6.11e-02 6.89e-01
REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING 25 2.52e-01 1.32e-01 6.89e-01
REACTOME SIGNALING BY VEGF 102 2.53e-01 -6.54e-02 6.91e-01
REACTOME SCAVENGING BY CLASS F RECEPTORS 6 2.54e-01 2.69e-01 6.91e-01
REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS 6 2.54e-01 2.69e-01 6.91e-01
REACTOME NRCAM INTERACTIONS 6 2.55e-01 2.68e-01 6.92e-01
REACTOME CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND 9 2.55e-01 -2.19e-01 6.92e-01
REACTOME METHIONINE SALVAGE PATHWAY 6 2.56e-01 -2.68e-01 6.92e-01
REACTOME PYRUVATE METABOLISM 29 2.57e-01 -1.22e-01 6.93e-01
REACTOME AQUAPORIN MEDIATED TRANSPORT 51 2.57e-01 9.17e-02 6.93e-01
REACTOME RAB GERANYLGERANYLATION 57 2.59e-01 -8.64e-02 6.93e-01
REACTOME PCP CE PATHWAY 91 2.59e-01 -6.85e-02 6.93e-01
REACTOME MASTL FACILITATES MITOTIC PROGRESSION 10 2.60e-01 2.06e-01 6.93e-01
REACTOME CELLULAR RESPONSE TO STARVATION 147 2.60e-01 -5.38e-02 6.93e-01
REACTOME REPRODUCTION 136 2.60e-01 -5.60e-02 6.93e-01
REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE 52 2.60e-01 -9.03e-02 6.93e-01
REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY 25 2.60e-01 -1.30e-01 6.93e-01
REACTOME GLYCEROPHOSPHOLIPID CATABOLISM 7 2.61e-01 -2.46e-01 6.93e-01
REACTOME INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE 20 2.61e-01 -1.45e-01 6.93e-01
REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS 62 2.61e-01 -8.25e-02 6.93e-01
REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS 63 2.63e-01 -8.16e-02 6.94e-01
REACTOME TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE 20 2.63e-01 -1.45e-01 6.94e-01
REACTOME IRAK1 RECRUITS IKK COMPLEX 12 2.63e-01 -1.87e-01 6.94e-01
REACTOME INTERLEUKIN 10 SIGNALING 43 2.64e-01 9.85e-02 6.95e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX3 94 2.64e-01 -6.66e-02 6.95e-01
REACTOME SARS COV 2 ACTIVATES MODULATES INNATE AND ADAPTIVE IMMUNE RESPONSES 118 2.65e-01 -5.94e-02 6.97e-01
REACTOME GLYCOSAMINOGLYCAN METABOLISM 118 2.66e-01 -5.93e-02 6.98e-01
REACTOME MITOPHAGY 28 2.67e-01 -1.21e-01 6.98e-01
REACTOME HSF1 ACTIVATION 29 2.67e-01 -1.19e-01 6.98e-01
REACTOME FANCONI ANEMIA PATHWAY 35 2.70e-01 -1.08e-01 7.04e-01
REACTOME DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE 17 2.71e-01 -1.54e-01 7.05e-01
REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS 21 2.71e-01 -1.39e-01 7.05e-01
REACTOME MATURATION OF SARS COV 2 NUCLEOPROTEIN 15 2.72e-01 -1.64e-01 7.05e-01
REACTOME SULFUR AMINO ACID METABOLISM 27 2.73e-01 -1.22e-01 7.05e-01
REACTOME MET ACTIVATES RAS SIGNALING 11 2.73e-01 -1.91e-01 7.05e-01
REACTOME 2 LTR CIRCLE FORMATION 7 2.73e-01 -2.39e-01 7.05e-01
REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY 29 2.73e-01 -1.18e-01 7.05e-01
REACTOME TELOMERE MAINTENANCE 106 2.74e-01 -6.15e-02 7.06e-01
REACTOME NUCLEAR PORE COMPLEX NPC DISASSEMBLY 36 2.75e-01 -1.05e-01 7.06e-01
REACTOME FRS MEDIATED FGFR1 SIGNALING 23 2.75e-01 -1.31e-01 7.06e-01
REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE 11 2.75e-01 1.90e-01 7.06e-01
REACTOME RA BIOSYNTHESIS PATHWAY 22 2.76e-01 1.34e-01 7.08e-01
REACTOME ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION 28 2.78e-01 1.18e-01 7.11e-01
REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI 17 2.79e-01 -1.52e-01 7.11e-01
REACTOME LRR FLII INTERACTING PROTEIN 1 LRRFIP1 ACTIVATES TYPE I IFN PRODUCTION 5 2.79e-01 -2.79e-01 7.11e-01
REACTOME REGULATION OF BETA CELL DEVELOPMENT 41 2.79e-01 -9.76e-02 7.11e-01
REACTOME RHO GTPASE EFFECTORS 305 2.80e-01 -3.60e-02 7.12e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL 15 2.81e-01 1.61e-01 7.12e-01
REACTOME INTERLEUKIN 1 PROCESSING 9 2.81e-01 2.08e-01 7.12e-01
REACTOME REGULATION OF GENE EXPRESSION IN ENDOCRINE COMMITTED NEUROG3 PROGENITOR CELLS 5 2.82e-01 -2.78e-01 7.13e-01
REACTOME FRS MEDIATED FGFR2 SIGNALING 24 2.82e-01 -1.27e-01 7.13e-01
REACTOME FORMATION OF TC NER PRE INCISION COMPLEX 51 2.83e-01 -8.70e-02 7.13e-01
REACTOME MRNA SPLICING 197 2.84e-01 -4.43e-02 7.14e-01
REACTOME UCH PROTEINASES 99 2.84e-01 -6.23e-02 7.14e-01
REACTOME CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS 19 2.85e-01 -1.42e-01 7.15e-01
REACTOME SHC RELATED EVENTS TRIGGERED BY IGF1R 9 2.87e-01 -2.05e-01 7.18e-01
REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES 21 2.87e-01 -1.34e-01 7.18e-01
REACTOME DNA METHYLATION 58 2.88e-01 -8.07e-02 7.18e-01
REACTOME MITOTIC PROMETAPHASE 194 2.88e-01 -4.43e-02 7.18e-01
REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS 60 2.88e-01 -7.93e-02 7.18e-01
REACTOME VLDL CLEARANCE 6 2.88e-01 2.50e-01 7.18e-01
REACTOME TYROSINE CATABOLISM 5 2.90e-01 2.74e-01 7.19e-01
REACTOME EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION 27 2.92e-01 -1.17e-01 7.23e-01
REACTOME INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL 14 2.92e-01 -1.63e-01 7.23e-01
REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX 31 2.92e-01 1.09e-01 7.23e-01
REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS 27 2.94e-01 -1.17e-01 7.25e-01
REACTOME RHO GTPASES ACTIVATE IQGAPS 31 2.94e-01 -1.09e-01 7.25e-01
REACTOME ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT 23 2.95e-01 -1.26e-01 7.27e-01
REACTOME COMMON PATHWAY OF FIBRIN CLOT FORMATION 21 2.96e-01 1.32e-01 7.28e-01
REACTOME ONCOGENIC MAPK SIGNALING 79 2.98e-01 -6.78e-02 7.31e-01
REACTOME AMINE LIGAND BINDING RECEPTORS 40 2.99e-01 9.50e-02 7.31e-01
REACTOME MICRORNA MIRNA BIOGENESIS 25 2.99e-01 -1.20e-01 7.31e-01
REACTOME LTC4 CYSLTR MEDIATED IL4 PRODUCTION 6 3.00e-01 -2.45e-01 7.31e-01
REACTOME ABACAVIR TRANSMEMBRANE TRANSPORT 5 3.00e-01 2.68e-01 7.31e-01
REACTOME INTESTINAL ABSORPTION 5 3.01e-01 2.67e-01 7.31e-01
REACTOME KERATAN SULFATE BIOSYNTHESIS 28 3.01e-01 -1.13e-01 7.31e-01
REACTOME ACTIVATION OF C3 AND C5 6 3.01e-01 2.44e-01 7.31e-01
REACTOME FRS MEDIATED FGFR3 SIGNALING 19 3.01e-01 -1.37e-01 7.31e-01
REACTOME GPER1 SIGNALING 45 3.02e-01 8.90e-02 7.31e-01
REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION 60 3.02e-01 -7.70e-02 7.31e-01
REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA 28 3.03e-01 1.13e-01 7.31e-01
REACTOME PLATELET CALCIUM HOMEOSTASIS 27 3.05e-01 -1.14e-01 7.33e-01
REACTOME TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION 5 3.05e-01 -2.65e-01 7.33e-01
REACTOME SIGNALING BY NTRK2 TRKB 25 3.05e-01 -1.19e-01 7.33e-01
REACTOME SHC1 EVENTS IN ERBB4 SIGNALING 14 3.06e-01 -1.58e-01 7.34e-01
REACTOME SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER 54 3.06e-01 -8.05e-02 7.34e-01
REACTOME METABOLISM OF AMINE DERIVED HORMONES 17 3.07e-01 -1.43e-01 7.34e-01
REACTOME ESTROGEN BIOSYNTHESIS 6 3.07e-01 2.41e-01 7.34e-01
REACTOME INTRA GOLGI TRAFFIC 43 3.08e-01 -8.99e-02 7.34e-01
REACTOME DEFECTIVE CHST14 CAUSES EDS MUSCULOCONTRACTURAL TYPE 7 3.09e-01 -2.22e-01 7.36e-01
REACTOME RHOC GTPASE CYCLE 71 3.09e-01 -6.98e-02 7.36e-01
REACTOME ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA 5 3.10e-01 2.62e-01 7.36e-01
REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR 19 3.11e-01 1.34e-01 7.37e-01
REACTOME RAF INDEPENDENT MAPK1 3 ACTIVATION 22 3.12e-01 -1.25e-01 7.38e-01
REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR 11 3.12e-01 -1.76e-01 7.38e-01
REACTOME PEXOPHAGY 11 3.13e-01 -1.76e-01 7.39e-01
REACTOME LAGGING STRAND SYNTHESIS 19 3.13e-01 -1.34e-01 7.39e-01
REACTOME DRUG MEDIATED INHIBITION OF CDK4 CDK6 ACTIVITY 5 3.14e-01 -2.60e-01 7.39e-01
REACTOME ZINC TRANSPORTERS 15 3.15e-01 -1.50e-01 7.40e-01
REACTOME SHC MEDIATED CASCADE FGFR1 21 3.15e-01 -1.27e-01 7.40e-01
REACTOME CD28 DEPENDENT PI3K AKT SIGNALING 22 3.18e-01 -1.23e-01 7.44e-01
REACTOME GAP JUNCTION ASSEMBLY 36 3.18e-01 9.62e-02 7.44e-01
REACTOME INSULIN RECEPTOR RECYCLING 29 3.18e-01 1.07e-01 7.44e-01
REACTOME PTK6 EXPRESSION 5 3.19e-01 -2.58e-01 7.44e-01
REACTOME NETRIN MEDIATED REPULSION SIGNALS 8 3.22e-01 2.02e-01 7.50e-01
REACTOME PROCESSING OF SMDT1 16 3.22e-01 -1.43e-01 7.50e-01
REACTOME HDACS DEACETYLATE HISTONES 85 3.23e-01 -6.20e-02 7.51e-01
REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL 41 3.25e-01 -8.88e-02 7.54e-01
REACTOME INTERFERON GAMMA SIGNALING 88 3.26e-01 -6.05e-02 7.54e-01
REACTOME BASE EXCISION REPAIR AP SITE FORMATION 59 3.27e-01 -7.39e-02 7.54e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR4 26 3.27e-01 -1.11e-01 7.54e-01
REACTOME FRUCTOSE METABOLISM 7 3.27e-01 2.14e-01 7.54e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX2 117 3.27e-01 -5.24e-02 7.55e-01
REACTOME CREB PHOSPHORYLATION 6 3.29e-01 -2.30e-01 7.55e-01
REACTOME RNA POLYMERASE I PROMOTER ESCAPE 83 3.29e-01 -6.19e-02 7.55e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH CDK5 6 3.30e-01 -2.30e-01 7.55e-01
REACTOME OPSINS 7 3.30e-01 2.13e-01 7.55e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX 19 3.30e-01 -1.29e-01 7.55e-01
REACTOME MUSCLE CONTRACTION 197 3.31e-01 4.02e-02 7.55e-01
REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX 14 3.31e-01 -1.50e-01 7.55e-01
REACTOME RIP MEDIATED NFKB ACTIVATION VIA ZBP1 16 3.32e-01 -1.40e-01 7.57e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS 11 3.33e-01 1.69e-01 7.57e-01
REACTOME SERINE BIOSYNTHESIS 9 3.33e-01 -1.86e-01 7.57e-01
REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE 20 3.35e-01 -1.25e-01 7.61e-01
REACTOME DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA 77 3.36e-01 -6.34e-02 7.62e-01
REACTOME DNA DAMAGE REVERSAL 8 3.37e-01 1.96e-01 7.62e-01
REACTOME IRS ACTIVATION 5 3.38e-01 2.48e-01 7.62e-01
REACTOME FCGR3A MEDIATED IL10 SYNTHESIS 36 3.39e-01 -9.21e-02 7.62e-01
REACTOME INTEGRATION OF ENERGY METABOLISM 105 3.39e-01 5.40e-02 7.62e-01
REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR 79 3.39e-01 -6.22e-02 7.62e-01
REACTOME FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS 8 3.39e-01 1.95e-01 7.62e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS 6 3.40e-01 2.25e-01 7.62e-01
REACTOME RECEPTOR MEDIATED MITOPHAGY 10 3.40e-01 -1.74e-01 7.62e-01
REACTOME PURINE CATABOLISM 17 3.40e-01 -1.34e-01 7.62e-01
REACTOME BIOLOGICAL OXIDATIONS 210 3.42e-01 3.81e-02 7.63e-01
REACTOME NUCLEAR ENVELOPE BREAKDOWN 52 3.42e-01 -7.61e-02 7.63e-01
REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 19 3.42e-01 -1.26e-01 7.63e-01
REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS 35 3.43e-01 -9.27e-02 7.63e-01
REACTOME EPHB MEDIATED FORWARD SIGNALING 41 3.43e-01 -8.56e-02 7.63e-01
REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION 62 3.45e-01 -6.93e-02 7.67e-01
REACTOME NR1H2 AND NR1H3 MEDIATED SIGNALING 46 3.47e-01 8.01e-02 7.67e-01
REACTOME SIGNALING BY EGFR IN CANCER 25 3.47e-01 -1.09e-01 7.67e-01
REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS 113 3.47e-01 -5.12e-02 7.67e-01
REACTOME CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER 25 3.47e-01 -1.09e-01 7.67e-01
REACTOME SHC MEDIATED CASCADE FGFR3 17 3.48e-01 -1.32e-01 7.67e-01
REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS 5 3.48e-01 2.42e-01 7.67e-01
REACTOME DEGRADATION OF AXIN 54 3.48e-01 -7.38e-02 7.67e-01
REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3 59 3.49e-01 -7.05e-02 7.67e-01
REACTOME PI5P REGULATES TP53 ACETYLATION 9 3.50e-01 -1.80e-01 7.68e-01
REACTOME MAPK3 ERK1 ACTIVATION 10 3.50e-01 -1.71e-01 7.68e-01
REACTOME REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS 11 3.52e-01 -1.62e-01 7.70e-01
REACTOMEMATURATION OF SARS COV 1 NUCLEOPROTEIN 11 3.52e-01 -1.62e-01 7.70e-01
REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES 353 3.53e-01 -2.88e-02 7.70e-01
REACTOME ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING 23 3.54e-01 -1.12e-01 7.71e-01
REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET 8 3.55e-01 1.89e-01 7.71e-01
REACTOME REGULATION OF RUNX1 EXPRESSION AND ACTIVITY 17 3.55e-01 -1.30e-01 7.71e-01
REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND 21 3.55e-01 1.16e-01 7.71e-01
REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND 14 3.56e-01 -1.43e-01 7.71e-01
REACTOME CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION 24 3.56e-01 1.09e-01 7.71e-01
REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS 11 3.58e-01 -1.60e-01 7.73e-01
REACTOME FCERI MEDIATED CA 2 MOBILIZATION 30 3.59e-01 -9.68e-02 7.73e-01
REACTOME KILLING MECHANISMS 11 3.59e-01 -1.60e-01 7.73e-01
REACTOME REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM 11 3.59e-01 1.60e-01 7.73e-01
REACTOME REGULATED NECROSIS 57 3.59e-01 -7.02e-02 7.73e-01
REACTOME DEFECTIVE CHSY1 CAUSES TPBS 7 3.60e-01 -2.00e-01 7.73e-01
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL 122 3.61e-01 -4.79e-02 7.73e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES 8 3.61e-01 -1.87e-01 7.73e-01
REACTOME RHO GTPASES ACTIVATE KTN1 11 3.62e-01 -1.59e-01 7.73e-01
REACTOME PD 1 SIGNALING 21 3.62e-01 1.15e-01 7.73e-01
REACTOME REGULATION BY C FLIP 11 3.63e-01 -1.58e-01 7.73e-01
REACTOME ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA 9 3.63e-01 1.75e-01 7.73e-01
REACTOME SIGNALING BY NTRK3 TRKC 17 3.63e-01 -1.27e-01 7.73e-01
REACTOME HSF1 DEPENDENT TRANSACTIVATION 37 3.63e-01 -8.63e-02 7.73e-01
REACTOME SYNDECAN INTERACTIONS 26 3.64e-01 1.03e-01 7.73e-01
REACTOME CHONDROITIN SULFATE BIOSYNTHESIS 18 3.65e-01 -1.23e-01 7.74e-01
REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING 89 3.65e-01 -5.55e-02 7.74e-01
REACTOME GLYCOGEN STORAGE DISEASES 15 3.66e-01 -1.35e-01 7.74e-01
REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING 12 3.66e-01 -1.51e-01 7.74e-01
REACTOME FORMATION OF INCISION COMPLEX IN GG NER 40 3.67e-01 -8.24e-02 7.74e-01
REACTOME CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE 49 3.68e-01 7.44e-02 7.74e-01
REACTOME EICOSANOID LIGAND BINDING RECEPTORS 14 3.68e-01 1.39e-01 7.74e-01
REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX 57 3.69e-01 -6.88e-02 7.75e-01
REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING 34 3.69e-01 -8.90e-02 7.75e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION 41 3.70e-01 8.10e-02 7.75e-01
REACTOME TELOMERE C STRAND SYNTHESIS INITIATION 12 3.70e-01 1.49e-01 7.75e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION 36 3.71e-01 8.61e-02 7.76e-01
REACTOME ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS 20 3.72e-01 -1.15e-01 7.76e-01
REACTOME PEROXISOMAL LIPID METABOLISM 28 3.73e-01 9.72e-02 7.79e-01
REACTOME PLASMA LIPOPROTEIN CLEARANCE 37 3.74e-01 8.45e-02 7.79e-01
REACTOME SYNTHESIS OF LIPOXINS LX 6 3.75e-01 2.09e-01 7.79e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER 28 3.75e-01 9.69e-02 7.79e-01
REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE 48 3.75e-01 -7.40e-02 7.79e-01
REACTOME FOLDING OF ACTIN BY CCT TRIC 10 3.78e-01 1.61e-01 7.82e-01
REACTOME RUNX2 REGULATES BONE DEVELOPMENT 29 3.79e-01 -9.45e-02 7.82e-01
REACTOME MET ACTIVATES PI3K AKT SIGNALING 6 3.79e-01 -2.07e-01 7.82e-01
REACTOME PYRIMIDINE CATABOLISM 12 3.79e-01 -1.47e-01 7.82e-01
REACTOME ANCHORING FIBRIL FORMATION 13 3.79e-01 1.41e-01 7.82e-01
REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE 16 3.80e-01 -1.27e-01 7.82e-01
REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION 68 3.80e-01 -6.15e-02 7.82e-01
REACTOME FORMATION OF LATERAL PLATE MESODERM 5 3.81e-01 -2.26e-01 7.83e-01
REACTOME GLYCOGEN SYNTHESIS 13 3.81e-01 -1.40e-01 7.83e-01
REACTOME SIGNALING BY ACTIVIN 15 3.82e-01 -1.30e-01 7.84e-01
REACTOME ALK MUTANTS BIND TKIS 12 3.85e-01 -1.45e-01 7.87e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST 14 3.85e-01 -1.34e-01 7.88e-01
REACTOME STIMULI SENSING CHANNELS 100 3.86e-01 -5.02e-02 7.88e-01
REACTOME GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION 7 3.86e-01 1.89e-01 7.88e-01
REACTOME S PHASE 159 3.88e-01 -3.97e-02 7.88e-01
REACTOME ADRENOCEPTORS 9 3.88e-01 -1.66e-01 7.88e-01
REACTOME TRIGLYCERIDE METABOLISM 35 3.88e-01 -8.44e-02 7.88e-01
REACTOME P2Y RECEPTORS 9 3.89e-01 1.66e-01 7.89e-01
REACTOME RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR 19 3.89e-01 -1.14e-01 7.89e-01
REACTOME HS GAG BIOSYNTHESIS 28 3.91e-01 -9.36e-02 7.92e-01
REACTOME DEFECTS IN BIOTIN BTN METABOLISM 8 3.92e-01 1.75e-01 7.93e-01
REACTOME SODIUM COUPLED PHOSPHATE COTRANSPORTERS 5 3.93e-01 -2.21e-01 7.93e-01
REACTOME DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX 83 3.95e-01 -5.41e-02 7.95e-01
REACTOME SIGNALING BY NOTCH1 T 7 9 NOTCH1 M1580 K2555 TRANSLOCATION MUTANT 7 3.95e-01 1.86e-01 7.95e-01
REACTOME TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY 16 3.95e-01 -1.23e-01 7.95e-01
REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE 277 3.96e-01 -2.96e-02 7.97e-01
REACTOME GLUTATHIONE CONJUGATION 33 3.97e-01 -8.52e-02 7.97e-01
REACTOME NEUROTRANSMITTER CLEARANCE 9 3.98e-01 -1.63e-01 7.98e-01
REACTOME COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING 32 4.00e-01 -8.59e-02 8.02e-01
REACTOME MAPK1 ERK2 ACTIVATION 9 4.01e-01 -1.62e-01 8.02e-01
REACTOME PRE NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM 6 4.02e-01 -1.97e-01 8.04e-01
REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS 37 4.04e-01 -7.94e-02 8.04e-01
REACTOME NUCLEAR EVENTS MEDIATED BY NFE2L2 77 4.04e-01 -5.51e-02 8.04e-01
REACTOME RHOA GTPASE CYCLE 142 4.04e-01 -4.05e-02 8.05e-01
REACTOME CYTOSOLIC TRNA AMINOACYLATION 22 4.05e-01 -1.03e-01 8.05e-01
REACTOME MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS 7 4.08e-01 -1.81e-01 8.10e-01
REACTOME REGULATION OF RAS BY GAPS 66 4.08e-01 -5.89e-02 8.10e-01
REACTOME GABA B RECEPTOR ACTIVATION 43 4.09e-01 7.27e-02 8.10e-01
REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION 9 4.11e-01 -1.58e-01 8.10e-01
REACTOME DISEASES OF GLYCOSYLATION 137 4.11e-01 -4.07e-02 8.10e-01
REACTOME INDUCTION OF CELL CELL FUSION 12 4.11e-01 -1.37e-01 8.10e-01
REACTOME TYSND1 CLEAVES PEROXISOMAL PROTEINS 7 4.11e-01 1.79e-01 8.10e-01
REACTOME RHOJ GTPASE CYCLE 51 4.11e-01 -6.65e-02 8.10e-01
REACTOME PROLACTIN RECEPTOR SIGNALING 15 4.12e-01 1.22e-01 8.10e-01
REACTOME KINESINS 59 4.13e-01 -6.16e-02 8.11e-01
REACTOME PROTEIN LOCALIZATION 153 4.15e-01 -3.82e-02 8.15e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS 14 4.16e-01 1.25e-01 8.16e-01
REACTOME PREGNENOLONE BIOSYNTHESIS 12 4.17e-01 1.35e-01 8.16e-01
REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING 32 4.20e-01 -8.23e-02 8.20e-01
REACTOME SIGNALING BY ERBB2 IN CANCER 26 4.21e-01 -9.13e-02 8.20e-01
REACTOME SYNTHESIS OF PG 8 4.22e-01 -1.64e-01 8.20e-01
REACTOME NUCLEOTIDE CATABOLISM 35 4.22e-01 -7.84e-02 8.20e-01
REACTOME ATTENUATION PHASE 27 4.23e-01 -8.91e-02 8.20e-01
REACTOME DEX H BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION 7 4.23e-01 -1.75e-01 8.20e-01
REACTOME MUSCARINIC ACETYLCHOLINE RECEPTORS 5 4.23e-01 -2.07e-01 8.20e-01
REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES 37 4.23e-01 -7.61e-02 8.20e-01
REACTOME SYNTHESIS OF DOLICHYL PHOSPHATE 6 4.24e-01 -1.89e-01 8.20e-01
REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING 33 4.24e-01 -8.04e-02 8.20e-01
REACTOME RNA POLYMERASE II PRE TRANSCRIPTION EVENTS 77 4.26e-01 -5.25e-02 8.21e-01
REACTOME NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION 193 4.26e-01 -3.32e-02 8.21e-01
REACTOME DUAL INCISION IN TC NER 63 4.26e-01 -5.80e-02 8.21e-01
REACTOME FATTY ACID METABOLISM 170 4.26e-01 3.54e-02 8.21e-01
REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES 38 4.27e-01 -7.45e-02 8.21e-01
REACTOME SEROTONIN RECEPTORS 11 4.28e-01 1.38e-01 8.22e-01
REACTOME MAPK FAMILY SIGNALING CASCADES 314 4.30e-01 -2.59e-02 8.24e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH PI3K 6 4.30e-01 1.86e-01 8.24e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2 17 4.32e-01 -1.10e-01 8.28e-01
REACTOME HEMOSTASIS 591 4.34e-01 -1.88e-02 8.29e-01
REACTOME PI3K AKT SIGNALING IN CANCER 103 4.37e-01 -4.44e-02 8.32e-01
REACTOME COPII MEDIATED VESICLE TRANSPORT 66 4.37e-01 -5.53e-02 8.32e-01
REACTOME GRB2 EVENTS IN ERBB2 SIGNALING 16 4.38e-01 -1.12e-01 8.32e-01
REACTOME SARS COV 1 INFECTION 136 4.38e-01 -3.85e-02 8.32e-01
REACTOME ARYL HYDROCARBON RECEPTOR SIGNALLING 6 4.38e-01 -1.83e-01 8.32e-01
REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS 8 4.40e-01 -1.58e-01 8.36e-01
REACTOME REGULATION OF LIPID METABOLISM BY PPARALPHA 115 4.41e-01 -4.16e-02 8.36e-01
REACTOME NEGATIVE REGULATION OF FLT3 15 4.41e-01 -1.15e-01 8.36e-01
REACTOME DEADENYLATION OF MRNA 25 4.43e-01 -8.87e-02 8.37e-01
REACTOME NEPHRIN FAMILY INTERACTIONS 22 4.43e-01 -9.44e-02 8.37e-01
REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS 30 4.46e-01 8.05e-02 8.38e-01
REACTOME LIPID PARTICLE ORGANIZATION 6 4.46e-01 1.80e-01 8.38e-01
REACTOME CONSTITUTIVE SIGNALING BY EGFRVIII 15 4.47e-01 -1.13e-01 8.38e-01
REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B 24 4.48e-01 -8.96e-02 8.38e-01
REACTOME PREDNISONE ADME 10 4.48e-01 -1.39e-01 8.38e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING 6 4.48e-01 -1.79e-01 8.38e-01
REACTOME MEIOTIC SYNAPSIS 73 4.48e-01 -5.13e-02 8.38e-01
REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION 32 4.48e-01 7.74e-02 8.38e-01
REACTOME ANTIGEN PROCESSING CROSS PRESENTATION 98 4.48e-01 -4.43e-02 8.38e-01
REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE 10 4.49e-01 -1.38e-01 8.38e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS 14 4.50e-01 1.17e-01 8.38e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1 31 4.51e-01 -7.83e-02 8.38e-01
REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS 11 4.51e-01 1.31e-01 8.38e-01
REACTOME FGFR1B LIGAND BINDING AND ACTIVATION 6 4.51e-01 1.78e-01 8.38e-01
REACTOME HS GAG DEGRADATION 19 4.51e-01 -9.98e-02 8.38e-01
REACTOME REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS 15 4.52e-01 -1.12e-01 8.38e-01
REACTOME SIGNALING BY BMP 27 4.53e-01 -8.35e-02 8.38e-01
REACTOME REGULATION OF PTEN LOCALIZATION 8 4.53e-01 -1.53e-01 8.38e-01
REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT 15 4.54e-01 1.12e-01 8.38e-01
REACTOME METABOLISM OF NUCLEOTIDES 94 4.54e-01 -4.47e-02 8.38e-01
REACTOME PREVENTION OF PHAGOSOMAL LYSOSOMAL FUSION 9 4.56e-01 -1.44e-01 8.39e-01
REACTOME NEF MEDIATED CD8 DOWN REGULATION 7 4.56e-01 1.63e-01 8.39e-01
REACTOME MELANIN BIOSYNTHESIS 5 4.56e-01 -1.92e-01 8.39e-01
REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX 32 4.57e-01 -7.60e-02 8.39e-01
REACTOME DOWNREGULATION OF ERBB2 SIGNALING 29 4.57e-01 -7.98e-02 8.39e-01
REACTOME TRANSPORT OF ORGANIC ANIONS 10 4.57e-01 1.36e-01 8.39e-01
REACTOME PINK1 PRKN MEDIATED MITOPHAGY 22 4.59e-01 -9.12e-02 8.41e-01
REACTOME IRS MEDIATED SIGNALLING 47 4.60e-01 -6.23e-02 8.42e-01
REACTOME PI3K EVENTS IN ERBB4 SIGNALING 10 4.61e-01 -1.35e-01 8.42e-01
REACTOME RIPK1 MEDIATED REGULATED NECROSIS 30 4.63e-01 -7.75e-02 8.42e-01
REACTOME EXTRACELLULAR MATRIX ORGANIZATION 291 4.63e-01 2.50e-02 8.42e-01
REACTOME CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY 12 4.63e-01 -1.22e-01 8.42e-01
REACTOME TOXICITY OF BOTULINUM TOXIN TYPE D BOTD 5 4.64e-01 -1.89e-01 8.42e-01
REACTOME FRS MEDIATED FGFR4 SIGNALING 21 4.65e-01 -9.22e-02 8.42e-01
REACTOME CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT 19 4.66e-01 -9.66e-02 8.42e-01
REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS 28 4.66e-01 -7.96e-02 8.42e-01
REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL 12 4.68e-01 -1.21e-01 8.42e-01
REACTOME IRE1ALPHA ACTIVATES CHAPERONES 48 4.68e-01 6.06e-02 8.42e-01
REACTOME SMALL INTERFERING RNA SIRNA BIOGENESIS 9 4.68e-01 -1.40e-01 8.42e-01
REACTOME ORGANIC ANION TRANSPORT 5 4.68e-01 1.87e-01 8.42e-01
REACTOME ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM 12 4.68e-01 1.21e-01 8.42e-01
REACTOME SIGNALING BY NOTCH1 69 4.68e-01 -5.05e-02 8.42e-01
REACTOME RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS 9 4.69e-01 1.40e-01 8.42e-01
REACTOME INTERLEUKIN 6 FAMILY SIGNALING 24 4.69e-01 -8.54e-02 8.42e-01
REACTOME ERBB2 REGULATES CELL MOTILITY 15 4.69e-01 1.08e-01 8.42e-01
REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING 28 4.69e-01 -7.90e-02 8.42e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE 5 4.70e-01 1.86e-01 8.43e-01
REACTOME CHL1 INTERACTIONS 9 4.74e-01 1.38e-01 8.44e-01
REACTOME ACYL CHAIN REMODELLING OF PE 29 4.75e-01 -7.67e-02 8.44e-01
REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R 52 4.75e-01 -5.73e-02 8.44e-01
REACTOME PLATELET HOMEOSTASIS 85 4.76e-01 4.48e-02 8.44e-01
REACTOME REGULATION OF RUNX3 EXPRESSION AND ACTIVITY 54 4.76e-01 -5.61e-02 8.44e-01
REACTOME TRIGLYCERIDE CATABOLISM 23 4.77e-01 -8.57e-02 8.44e-01
REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING 13 4.77e-01 -1.14e-01 8.44e-01
REACTOME G ALPHA Q SIGNALLING EVENTS 206 4.77e-01 2.87e-02 8.44e-01
REACTOME HDMS DEMETHYLATE HISTONES 40 4.78e-01 -6.49e-02 8.44e-01
REACTOME STRIATED MUSCLE CONTRACTION 35 4.78e-01 6.93e-02 8.44e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH CDC42 19 4.78e-01 9.40e-02 8.44e-01
REACTOME TAK1 DEPENDENT IKK AND NF KAPPA B ACTIVATION 41 4.78e-01 -6.40e-02 8.44e-01
REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK 17 4.78e-01 -9.94e-02 8.44e-01
REACTOME MITOCHONDRIAL UNCOUPLING 5 4.79e-01 -1.83e-01 8.44e-01
REACTOME KERATAN SULFATE KERATIN METABOLISM 34 4.79e-01 -7.01e-02 8.44e-01
REACTOME N GLYCAN TRIMMING AND ELONGATION IN THE CIS GOLGI 5 4.80e-01 -1.82e-01 8.44e-01
REACTOME EXTENSION OF TELOMERES 49 4.80e-01 -5.83e-02 8.44e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1 16 4.81e-01 -1.02e-01 8.44e-01
REACTOME PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS 21 4.82e-01 8.87e-02 8.44e-01
REACTOME NEGATIVE REGULATION OF MET ACTIVITY 20 4.82e-01 -9.09e-02 8.44e-01
REACTOME SYNTHESIS OF 5 EICOSATETRAENOIC ACIDS 9 4.82e-01 1.35e-01 8.44e-01
REACTOME ACTIVATION OF SMO 18 4.82e-01 -9.57e-02 8.44e-01
REACTOME DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS 14 4.83e-01 -1.08e-01 8.44e-01
REACTOME NEGATIVE REGULATION OF MAPK PATHWAY 41 4.87e-01 -6.27e-02 8.50e-01
REACTOME SHC1 EVENTS IN EGFR SIGNALING 14 4.87e-01 -1.07e-01 8.50e-01
REACTOME RHOBTB3 ATPASE CYCLE 8 4.87e-01 -1.42e-01 8.50e-01
REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION 32 4.88e-01 -7.08e-02 8.50e-01
REACTOME N GLYCAN ANTENNAE ELONGATION 15 4.89e-01 -1.03e-01 8.50e-01
REACTOME INTERLEUKIN RECEPTOR SHC SIGNALING 24 4.90e-01 -8.14e-02 8.51e-01
REACTOME FLT3 SIGNALING BY CBL MUTANTS 7 4.92e-01 -1.50e-01 8.52e-01
REACTOME O LINKED GLYCOSYLATION OF MUCINS 61 4.92e-01 5.09e-02 8.52e-01
REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS 20 4.92e-01 -8.87e-02 8.52e-01
REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS 81 4.93e-01 -4.41e-02 8.52e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE 8 4.93e-01 -1.40e-01 8.52e-01
REACTOME NADE MODULATES DEATH SIGNALLING 5 4.94e-01 -1.77e-01 8.52e-01
REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS 63 4.94e-01 -4.98e-02 8.53e-01
REACTOME BIOTIN TRANSPORT AND METABOLISM 10 4.95e-01 1.25e-01 8.54e-01
REACTOME ION HOMEOSTASIS 52 4.98e-01 5.43e-02 8.58e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES 12 5.01e-01 1.12e-01 8.60e-01
REACTOME METABOLISM OF STEROID HORMONES 35 5.01e-01 6.57e-02 8.60e-01
REACTOME PP2A MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS 6 5.01e-01 1.58e-01 8.60e-01
REACTOME CILIUM ASSEMBLY 190 5.04e-01 -2.81e-02 8.63e-01
REACTOME HDR THROUGH MMEJ ALT NHEJ 12 5.04e-01 -1.11e-01 8.63e-01
REACTOME PHENYLALANINE AND TYROSINE METABOLISM 11 5.05e-01 1.16e-01 8.64e-01
REACTOME PTK6 PROMOTES HIF1A STABILIZATION 6 5.06e-01 -1.57e-01 8.64e-01
REACTOME ACYL CHAIN REMODELLING OF PG 18 5.09e-01 -8.99e-02 8.69e-01
REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS 15 5.10e-01 -9.84e-02 8.69e-01
REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING 13 5.10e-01 -1.06e-01 8.69e-01
REACTOME NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 11 5.11e-01 1.14e-01 8.69e-01
REACTOME TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS 26 5.11e-01 7.45e-02 8.69e-01
REACTOME NFE2L2 REGULATING ANTI OXIDANT DETOXIFICATION ENZYMES 17 5.12e-01 -9.20e-02 8.69e-01
REACTOME OVARIAN TUMOR DOMAIN PROTEASES 36 5.12e-01 -6.31e-02 8.69e-01
REACTOME RET SIGNALING 40 5.18e-01 -5.91e-02 8.75e-01
REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL 13 5.18e-01 -1.04e-01 8.75e-01
REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION 13 5.18e-01 1.04e-01 8.75e-01
REACTOME REGULATION OF IFNA IFNB SIGNALING 23 5.18e-01 -7.78e-02 8.75e-01
REACTOME ACTIVATION OF AMPK DOWNSTREAM OF NMDARS 28 5.18e-01 -7.05e-02 8.75e-01
REACTOME NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 25 5.19e-01 7.44e-02 8.75e-01
REACTOME MYOGENESIS 29 5.20e-01 -6.91e-02 8.75e-01
REACTOME HDL ASSEMBLY 8 5.21e-01 1.31e-01 8.76e-01
REACTOME DEFENSINS 33 5.21e-01 6.45e-02 8.76e-01
REACTOME VLDLR INTERNALISATION AND DEGRADATION 16 5.22e-01 -9.24e-02 8.77e-01
REACTOME GAP JUNCTION TRAFFICKING AND REGULATION 49 5.23e-01 5.27e-02 8.77e-01
REACTOME REGULATION OF PTEN STABILITY AND ACTIVITY 67 5.23e-01 -4.51e-02 8.77e-01
REACTOME SUPPRESSION OF PHAGOSOMAL MATURATION 13 5.24e-01 -1.02e-01 8.78e-01
REACTOME EFFECTS OF PIP2 HYDROLYSIS 26 5.26e-01 -7.19e-02 8.78e-01
REACTOME INTERLEUKIN 18 SIGNALING 8 5.26e-01 -1.30e-01 8.78e-01
REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION 26 5.27e-01 7.17e-02 8.78e-01
REACTOME CYCLIN D ASSOCIATED EVENTS IN G1 46 5.27e-01 -5.39e-02 8.78e-01
REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES 12 5.27e-01 -1.05e-01 8.78e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES 43 5.28e-01 5.56e-02 8.79e-01
REACTOME DOPAMINE RECEPTORS 5 5.29e-01 1.62e-01 8.79e-01
REACTOME COLLAGEN CHAIN TRIMERIZATION 42 5.31e-01 5.59e-02 8.79e-01
REACTOME SIGNALING BY CSF1 M CSF IN MYELOID CELLS 30 5.31e-01 -6.61e-02 8.79e-01
REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS 29 5.32e-01 -6.71e-02 8.79e-01
REACTOME PKA ACTIVATION IN GLUCAGON SIGNALLING 17 5.32e-01 8.75e-02 8.79e-01
REACTOME RNA POLYMERASE II TRANSCRIBES SNRNA GENES 77 5.32e-01 -4.12e-02 8.79e-01
REACTOME NOTCH HLH TRANSCRIPTION PATHWAY 24 5.33e-01 -7.36e-02 8.79e-01
REACTOME SHC MEDIATED CASCADE FGFR4 19 5.33e-01 -8.27e-02 8.79e-01
REACTOME NUCLEOTIDE BIOSYNTHESIS 14 5.33e-01 9.62e-02 8.79e-01
REACTOME NGF INDEPENDANT TRKA ACTIVATION 5 5.34e-01 -1.61e-01 8.79e-01
REACTOME DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS 25 5.34e-01 7.18e-02 8.79e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS 5 5.38e-01 -1.59e-01 8.82e-01
REACTOME METABOLISM OF STEROIDS 150 5.38e-01 2.91e-02 8.82e-01
REACTOME TRANSPORT OF RCBL WITHIN THE BODY 8 5.38e-01 1.26e-01 8.82e-01
REACTOME CYP2E1 REACTIONS 10 5.39e-01 1.12e-01 8.82e-01
REACTOME G2 M DNA DAMAGE CHECKPOINT 90 5.40e-01 -3.74e-02 8.82e-01
REACTOME FOXO MEDIATED TRANSCRIPTION 65 5.40e-01 -4.40e-02 8.82e-01
REACTOME OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS 8 5.40e-01 1.25e-01 8.82e-01
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS 161 5.41e-01 -2.79e-02 8.82e-01
REACTOME LOSS OF FUNCTION OF SMAD2 3 IN CANCER 7 5.42e-01 -1.33e-01 8.82e-01
REACTOME RHO GTPASES ACTIVATE ROCKS 19 5.42e-01 -8.08e-02 8.82e-01
REACTOME G ALPHA 12 13 SIGNALLING EVENTS 74 5.42e-01 4.10e-02 8.82e-01
REACTOME SIGNAL ATTENUATION 10 5.43e-01 1.11e-01 8.82e-01
REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE 17 5.43e-01 -8.52e-02 8.82e-01
REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING 6 5.45e-01 -1.43e-01 8.84e-01
REACTOME METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES 33 5.46e-01 -6.07e-02 8.84e-01
REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING 29 5.46e-01 6.48e-02 8.84e-01
REACTOME NICOTINAMIDE SALVAGING 19 5.48e-01 -7.97e-02 8.84e-01
REACTOME MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS 13 5.48e-01 -9.62e-02 8.84e-01
REACTOME IRON UPTAKE AND TRANSPORT 56 5.48e-01 -4.64e-02 8.84e-01
REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION 9 5.50e-01 1.15e-01 8.84e-01
REACTOME TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS 82 5.50e-01 3.82e-02 8.84e-01
REACTOME TIE2 SIGNALING 18 5.51e-01 -8.13e-02 8.84e-01
REACTOME DISEASES OF CARBOHYDRATE METABOLISM 31 5.51e-01 -6.19e-02 8.84e-01
REACTOME MITOTIC TELOPHASE CYTOKINESIS 11 5.52e-01 1.04e-01 8.84e-01
REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX 9 5.52e-01 -1.15e-01 8.84e-01
REACTOME FATTY ACYL COA BIOSYNTHESIS 36 5.52e-01 -5.73e-02 8.84e-01
REACTOME NUCLEAR SIGNALING BY ERBB4 32 5.52e-01 6.07e-02 8.84e-01
REACTOME ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY 10 5.56e-01 -1.08e-01 8.87e-01
REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE 93 5.56e-01 -3.53e-02 8.87e-01
REACTOME LDL REMODELING 6 5.56e-01 1.39e-01 8.87e-01
REACTOME DNA DOUBLE STRAND BREAK RESPONSE 74 5.56e-01 -3.95e-02 8.87e-01
REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS 12 5.57e-01 -9.79e-02 8.87e-01
REACTOME INNATE IMMUNE SYSTEM 1002 5.58e-01 -1.09e-02 8.87e-01
REACTOME IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN 5 5.58e-01 1.51e-01 8.87e-01
REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES 27 5.59e-01 -6.49e-02 8.87e-01
REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY 23 5.60e-01 -7.02e-02 8.87e-01
REACTOME SIGNALING BY ERBB2 ECD MUTANTS 16 5.61e-01 -8.39e-02 8.87e-01
REACTOME PI3K AKT ACTIVATION 9 5.63e-01 -1.11e-01 8.87e-01
REACTOME ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS 5 5.63e-01 -1.49e-01 8.87e-01
REACTOME ACETYLCHOLINE REGULATES INSULIN SECRETION 10 5.64e-01 -1.05e-01 8.87e-01
REACTOME LYSINE CATABOLISM 12 5.64e-01 9.61e-02 8.87e-01
REACTOME ALPHA OXIDATION OF PHYTANATE 6 5.65e-01 1.36e-01 8.87e-01
REACTOME ECM PROTEOGLYCANS 73 5.67e-01 3.88e-02 8.87e-01
REACTOME OAS ANTIVIRAL RESPONSE 8 5.67e-01 1.17e-01 8.87e-01
REACTOME PI 3K CASCADE FGFR1 21 5.70e-01 -7.15e-02 8.87e-01
REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM 20 5.71e-01 7.33e-02 8.87e-01
REACTOME DNA STRAND ELONGATION 31 5.72e-01 -5.87e-02 8.87e-01
REACTOME METHYLATION 14 5.72e-01 -8.72e-02 8.87e-01
REACTOME SIGNALING BY NOTCH2 32 5.73e-01 -5.75e-02 8.87e-01
REACTOME SENSING OF DNA DOUBLE STRAND BREAKS 6 5.73e-01 -1.33e-01 8.87e-01
REACTOME IKBA VARIANT LEADS TO EDA ID 6 5.74e-01 -1.33e-01 8.87e-01
REACTOME PLATELET SENSITIZATION BY LDL 17 5.74e-01 7.88e-02 8.87e-01
REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY 72 5.75e-01 -3.83e-02 8.87e-01
REACTOME PI 3K CASCADE FGFR2 22 5.75e-01 -6.91e-02 8.87e-01
REACTOME SARS COV 2 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS 12 5.75e-01 -9.35e-02 8.87e-01
REACTOME CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2 11 5.75e-01 -9.76e-02 8.87e-01
REACTOME FGFR2C LIGAND BINDING AND ACTIVATION 12 5.76e-01 -9.33e-02 8.87e-01
REACTOME THE ACTIVATION OF ARYLSULFATASES 8 5.76e-01 -1.14e-01 8.87e-01
REACTOME SPRY REGULATION OF FGF SIGNALING 16 5.76e-01 -8.07e-02 8.87e-01
REACTOME PYROPTOSIS 27 5.78e-01 -6.19e-02 8.87e-01
REACTOME VITAMIN B2 RIBOFLAVIN METABOLISM 7 5.79e-01 -1.21e-01 8.87e-01
REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A 26 5.79e-01 -6.28e-02 8.87e-01
REACTOME PASSIVE TRANSPORT BY AQUAPORINS 13 5.79e-01 8.88e-02 8.87e-01
REACTOME DEGRADATION OF CYSTEINE AND HOMOCYSTEINE 15 5.79e-01 -8.26e-02 8.87e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES 61 5.80e-01 -4.09e-02 8.87e-01
REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS 23 5.80e-01 6.66e-02 8.87e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3 11 5.81e-01 -9.62e-02 8.87e-01
REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER 18 5.81e-01 -7.52e-02 8.87e-01
REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE 69 5.81e-01 -3.84e-02 8.87e-01
REACTOME GDP FUCOSE BIOSYNTHESIS 6 5.81e-01 -1.30e-01 8.87e-01
REACTOME RESOLUTION OF ABASIC SITES AP SITES 38 5.82e-01 -5.16e-02 8.87e-01
REACTOME P75NTR REGULATES AXONOGENESIS 9 5.82e-01 -1.06e-01 8.87e-01
REACTOME RHOBTB GTPASE CYCLE 34 5.83e-01 -5.44e-02 8.87e-01
REACTOME PHASE 4 RESTING MEMBRANE POTENTIAL 19 5.83e-01 -7.28e-02 8.87e-01
REACTOME SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL 25 5.83e-01 6.34e-02 8.87e-01
REACTOME BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA 5 5.83e-01 1.42e-01 8.87e-01
REACTOME REGULATION OF BACH1 ACTIVITY 11 5.83e-01 -9.55e-02 8.87e-01
REACTOME ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS 7 5.83e-01 -1.20e-01 8.87e-01
REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB 19 5.83e-01 7.27e-02 8.87e-01
REACTOME INOSITOL PHOSPHATE METABOLISM 45 5.84e-01 -4.72e-02 8.87e-01
REACTOME HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS 9 5.84e-01 1.05e-01 8.87e-01
REACTOME ENOS ACTIVATION 11 5.85e-01 -9.52e-02 8.87e-01
REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES 34 5.85e-01 5.42e-02 8.87e-01
REACTOME TRNA MODIFICATION IN THE MITOCHONDRION 8 5.85e-01 1.11e-01 8.87e-01
REACTOME TRNA AMINOACYLATION 40 5.87e-01 -4.97e-02 8.87e-01
REACTOME HEME DEGRADATION 15 5.87e-01 8.10e-02 8.87e-01
REACTOME C TYPE LECTIN RECEPTORS CLRS 136 5.87e-01 -2.69e-02 8.87e-01
REACTOME P75NTR SIGNALS VIA NF KB 15 5.88e-01 -8.08e-02 8.87e-01
REACTOME NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 22 5.88e-01 -6.67e-02 8.87e-01
REACTOME DARPP 32 EVENTS 24 5.88e-01 -6.38e-02 8.87e-01
REACTOME RND2 GTPASE CYCLE 42 5.89e-01 -4.82e-02 8.87e-01
REACTOME CELL CYCLE CHECKPOINTS 284 5.89e-01 -1.86e-02 8.87e-01
REACTOME PROSTANOID LIGAND RECEPTORS 9 5.90e-01 1.04e-01 8.87e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING 5 5.91e-01 -1.39e-01 8.87e-01
REACTOME SIGNALING BY MAPK MUTANTS 6 5.92e-01 -1.26e-01 8.87e-01
REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS 16 5.92e-01 -7.74e-02 8.87e-01
REACTOME FGFR2B LIGAND BINDING AND ACTIVATION 10 5.92e-01 9.79e-02 8.87e-01
REACTOME RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES TREGS 9 5.94e-01 -1.03e-01 8.88e-01
REACTOME RHOB GTPASE CYCLE 67 5.94e-01 -3.76e-02 8.88e-01
REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION 42 5.95e-01 4.75e-02 8.88e-01
REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC 26 5.95e-01 -6.03e-02 8.88e-01
REACTOME POLO LIKE KINASE MEDIATED EVENTS 16 5.95e-01 -7.67e-02 8.88e-01
REACTOME GENERATION OF SECOND MESSENGER MOLECULES 30 5.95e-01 -5.61e-02 8.88e-01
REACTOME DEFECTIVE EXT2 CAUSES EXOSTOSES 2 12 5.96e-01 -8.84e-02 8.88e-01
REACTOME RECYCLING PATHWAY OF L1 43 5.96e-01 -4.67e-02 8.88e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE 11 5.97e-01 9.20e-02 8.88e-01
REACTOME FERTILIZATION 26 5.97e-01 5.98e-02 8.88e-01
REACTOME RUNX3 REGULATES BCL2L11 BIM TRANSCRIPTION 5 5.99e-01 1.36e-01 8.88e-01
REACTOME RUNX3 REGULATES CDKN1A TRANSCRIPTION 7 6.00e-01 1.15e-01 8.88e-01
REACTOME CHOLINE CATABOLISM 6 6.00e-01 -1.24e-01 8.88e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN 21 6.01e-01 -6.59e-02 8.88e-01
REACTOME METABOLISM OF PORPHYRINS 26 6.02e-01 5.92e-02 8.88e-01
REACTOME GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION 42 6.02e-01 4.65e-02 8.88e-01
REACTOME MITOCHONDRIAL BIOGENESIS 87 6.02e-01 -3.23e-02 8.88e-01
REACTOME GAP JUNCTION DEGRADATION 12 6.03e-01 -8.67e-02 8.88e-01
REACTOME COLLAGEN FORMATION 88 6.03e-01 3.20e-02 8.88e-01
REACTOME HUR ELAVL1 BINDS AND STABILIZES MRNA 8 6.04e-01 -1.06e-01 8.88e-01
REACTOME CELL JUNCTION ORGANIZATION 89 6.04e-01 3.18e-02 8.88e-01
REACTOME G2 M CHECKPOINTS 162 6.04e-01 -2.36e-02 8.88e-01
REACTOME TRANSCRIPTIONAL REGULATION BY E2F6 32 6.05e-01 -5.28e-02 8.88e-01
REACTOME GLYCOLYSIS 70 6.06e-01 -3.57e-02 8.88e-01
REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION 10 6.06e-01 9.42e-02 8.88e-01
REACTOME RHO GTPASES ACTIVATE FORMINS 136 6.07e-01 -2.56e-02 8.89e-01
REACTOME PROTEIN METHYLATION 17 6.07e-01 -7.20e-02 8.89e-01
REACTOME VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS 42 6.08e-01 4.57e-02 8.89e-01
REACTOME ELASTIC FIBRE FORMATION 44 6.10e-01 -4.45e-02 8.91e-01
REACTOME SIGNALING BY HEDGEHOG 148 6.11e-01 -2.42e-02 8.91e-01
REACTOME CIPROFLOXACIN ADME 5 6.12e-01 -1.31e-01 8.91e-01
REACTOME SYNTHESIS OF DNA 119 6.12e-01 -2.69e-02 8.91e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1 25 6.13e-01 -5.85e-02 8.91e-01
REACTOME ARACHIDONIC ACID METABOLISM 57 6.13e-01 3.87e-02 8.91e-01
REACTOME BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA 5 6.13e-01 1.30e-01 8.91e-01
REACTOME TYPE I HEMIDESMOSOME ASSEMBLY 11 6.15e-01 8.77e-02 8.92e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER 28 6.18e-01 5.45e-02 8.95e-01
REACTOME ORC1 REMOVAL FROM CHROMATIN 70 6.18e-01 3.45e-02 8.95e-01
REACTOME SARS COV 1 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS 16 6.20e-01 -7.17e-02 8.97e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH RAS 8 6.20e-01 -1.01e-01 8.97e-01
REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI 26 6.21e-01 -5.60e-02 8.97e-01
REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS 91 6.22e-01 -2.99e-02 8.97e-01
REACTOME LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX 5 6.22e-01 -1.27e-01 8.97e-01
REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS 19 6.23e-01 6.52e-02 8.98e-01
REACTOME GLYCOGEN METABOLISM 22 6.24e-01 -6.04e-02 8.98e-01
REACTOME TRIGLYCERIDE BIOSYNTHESIS 12 6.25e-01 -8.16e-02 8.99e-01
REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING 30 6.25e-01 -5.15e-02 8.99e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12 22 6.26e-01 6.01e-02 8.99e-01
REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX 21 6.27e-01 6.13e-02 8.99e-01
REACTOME INACTIVATION OF CDC42 AND RAC1 8 6.27e-01 9.92e-02 8.99e-01
REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB 5 6.27e-01 1.25e-01 8.99e-01
REACTOME LIGAND RECEPTOR INTERACTIONS 8 6.29e-01 -9.88e-02 8.99e-01
REACTOME PEROXISOMAL PROTEIN IMPORT 62 6.29e-01 3.55e-02 8.99e-01
REACTOME EGFR TRANSACTIVATION BY GASTRIN 9 6.30e-01 -9.26e-02 8.99e-01
REACTOME DNA REPLICATION PRE INITIATION 150 6.30e-01 -2.28e-02 8.99e-01
REACTOME CHROMOSOME MAINTENANCE 130 6.32e-01 -2.44e-02 8.99e-01
REACTOME DEFECTIVE RIPK1 MEDIATED REGULATED NECROSIS 7 6.32e-01 -1.05e-01 8.99e-01
REACTOME DEFECTIVE B4GALT1 CAUSES B4GALT1 CDG CDG 2D 8 6.32e-01 9.78e-02 8.99e-01
REACTOME CONDENSATION OF PROPHASE CHROMOSOMES 66 6.32e-01 -3.41e-02 8.99e-01
REACTOME NONCANONICAL ACTIVATION OF NOTCH3 8 6.33e-01 9.75e-02 9.00e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH METHYLATION 19 6.35e-01 6.29e-02 9.02e-01
REACTOME NEF AND SIGNAL TRANSDUCTION 8 6.36e-01 -9.66e-02 9.03e-01
REACTOME PROTEIN REPAIR 6 6.37e-01 -1.11e-01 9.03e-01
REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION 11 6.37e-01 -8.22e-02 9.03e-01
REACTOME SYNTHESIS OF DIPHTHAMIDE EEF2 8 6.39e-01 9.59e-02 9.03e-01
REACTOME TACHYKININ RECEPTORS BIND TACHYKININS 5 6.39e-01 1.21e-01 9.03e-01
REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN 76 6.39e-01 -3.11e-02 9.03e-01
REACTOME INTERLEUKIN 1 FAMILY SIGNALING 146 6.40e-01 -2.24e-02 9.03e-01
REACTOME NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 11 6.40e-01 -8.15e-02 9.03e-01
REACTOME NEGATIVE REGULATION OF NOTCH4 SIGNALING 53 6.43e-01 3.68e-02 9.03e-01
REACTOME ROBO RECEPTORS BIND AKAP5 9 6.43e-01 -8.92e-02 9.03e-01
REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY 51 6.44e-01 3.74e-02 9.03e-01
REACTOME SIGNALING BY MRAS COMPLEX MUTANTS 7 6.44e-01 -1.01e-01 9.03e-01
REACTOME EUKARYOTIC TRANSLATION INITIATION 110 6.45e-01 2.55e-02 9.03e-01
REACTOME G2 M DNA REPLICATION CHECKPOINT 5 6.45e-01 -1.19e-01 9.03e-01
REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY 10 6.45e-01 8.42e-02 9.03e-01
REACTOME DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A 5 6.45e-01 1.19e-01 9.03e-01
REACTOME VITAMINS 6 6.45e-01 -1.09e-01 9.03e-01
REACTOME AURKA ACTIVATION BY TPX2 69 6.47e-01 -3.19e-02 9.05e-01
REACTOME MATURATION OF PROTEIN 3A 9 6.47e-01 8.81e-02 9.05e-01
REACTOME VITAMIN D CALCIFEROL METABOLISM 12 6.49e-01 7.58e-02 9.06e-01
REACTOME MISCELLANEOUS TRANSPORT AND BINDING EVENTS 24 6.50e-01 -5.36e-02 9.06e-01
REACTOME PI 3K CASCADE FGFR3 17 6.50e-01 -6.35e-02 9.06e-01
REACTOME RRNA PROCESSING 192 6.52e-01 -1.89e-02 9.08e-01
REACTOME ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION 16 6.53e-01 -6.48e-02 9.08e-01
REACTOME REGULATION OF PTEN MRNA TRANSLATION 9 6.54e-01 -8.62e-02 9.08e-01
REACTOME HYDROLYSIS OF LPC 9 6.54e-01 -8.61e-02 9.08e-01
REACTOME GAB1 SIGNALOSOME 17 6.55e-01 -6.26e-02 9.08e-01
REACTOME TERMINAL PATHWAY OF COMPLEMENT 8 6.55e-01 -9.11e-02 9.08e-01
REACTOME PROTEIN UBIQUITINATION 76 6.55e-01 -2.96e-02 9.08e-01
REACTOME PERK REGULATES GENE EXPRESSION 31 6.56e-01 -4.63e-02 9.08e-01
REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS 11 6.57e-01 7.74e-02 9.08e-01
REACTOME RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA 7 6.57e-01 -9.68e-02 9.08e-01
REACTOME NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION 20 6.58e-01 -5.71e-02 9.09e-01
REACTOME INSULIN RECEPTOR SIGNALLING CASCADE 53 6.60e-01 -3.50e-02 9.10e-01
REACTOME NICOTINATE METABOLISM 31 6.60e-01 -4.56e-02 9.10e-01
REACTOME SIGNALING BY NOTCH3 48 6.61e-01 -3.66e-02 9.11e-01
REACTOME DISSOLUTION OF FIBRIN CLOT 13 6.62e-01 7.01e-02 9.11e-01
REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE 20 6.62e-01 5.64e-02 9.11e-01
REACTOME GLUTAMATE AND GLUTAMINE METABOLISM 13 6.65e-01 -6.93e-02 9.13e-01
REACTOME VEGF LIGAND RECEPTOR INTERACTIONS 7 6.65e-01 9.44e-02 9.13e-01
REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS 15 6.66e-01 6.44e-02 9.13e-01
REACTOME RND3 GTPASE CYCLE 41 6.66e-01 -3.90e-02 9.13e-01
REACTOME HYALURONAN BIOSYNTHESIS AND EXPORT 5 6.67e-01 -1.11e-01 9.13e-01
REACTOME CARDIAC CONDUCTION 125 6.68e-01 2.22e-02 9.13e-01
REACTOME G ALPHA Z SIGNALLING EVENTS 48 6.68e-01 3.58e-02 9.13e-01
REACTOME SIGNALLING TO P38 VIA RIT AND RIN 5 6.68e-01 -1.11e-01 9.13e-01
REACTOME DCC MEDIATED ATTRACTIVE SIGNALING 14 6.69e-01 6.60e-02 9.13e-01
REACTOME FGFR1 LIGAND BINDING AND ACTIVATION 15 6.69e-01 -6.37e-02 9.13e-01
REACTOME RAC1 GTPASE CYCLE 172 6.71e-01 -1.88e-02 9.14e-01
REACTOME G PROTEIN ACTIVATION 24 6.72e-01 -4.99e-02 9.14e-01
REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE 21 6.73e-01 -5.32e-02 9.14e-01
REACTOME ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS 20 6.73e-01 -5.45e-02 9.14e-01
REACTOME IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS 17 6.73e-01 -5.91e-02 9.14e-01
REACTOME CONDENSATION OF PROMETAPHASE CHROMOSOMES 11 6.74e-01 -7.33e-02 9.14e-01
REACTOME IRAK4 DEFICIENCY TLR2 4 17 6.75e-01 5.88e-02 9.14e-01
REACTOME DSCAM INTERACTIONS 11 6.75e-01 -7.31e-02 9.14e-01
REACTOME VXPX CARGO TARGETING TO CILIUM 20 6.76e-01 5.39e-02 9.15e-01
REACTOME CALCITONIN LIKE LIGAND RECEPTORS 10 6.77e-01 -7.60e-02 9.16e-01
REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 122 6.78e-01 2.18e-02 9.16e-01
REACTOME IRF3 MEDIATED INDUCTION OF TYPE I IFN 13 6.78e-01 6.64e-02 9.16e-01
REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN 15 6.79e-01 -6.18e-02 9.16e-01
REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE 15 6.79e-01 -6.17e-02 9.16e-01
REACTOME MRNA CAPPING 28 6.80e-01 -4.50e-02 9.16e-01
REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS 32 6.81e-01 -4.20e-02 9.16e-01
REACTOME ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES 59 6.82e-01 3.09e-02 9.16e-01
REACTOME INFLAMMASOMES 21 6.82e-01 -5.17e-02 9.16e-01
REACTOME REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR 11 6.83e-01 7.12e-02 9.16e-01
REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES 39 6.83e-01 3.78e-02 9.16e-01
REACTOME ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA 15 6.84e-01 -6.07e-02 9.16e-01
REACTOME SIGNALING BY RNF43 MUTANTS 8 6.84e-01 8.31e-02 9.16e-01
REACTOME REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA 15 6.85e-01 -6.04e-02 9.16e-01
REACTOME ORGANIC CATION TRANSPORT 10 6.86e-01 7.39e-02 9.16e-01
REACTOME SUMO IS TRANSFERRED FROM E1 TO E2 UBE2I UBC9 7 6.86e-01 -8.81e-02 9.16e-01
REACTOME SENSORY PERCEPTION OF SALTY TASTE 6 6.87e-01 9.51e-02 9.16e-01
REACTOME DEFECTIVE GALNT3 CAUSES HFTC 16 6.88e-01 5.80e-02 9.16e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH RAS 9 6.89e-01 -7.72e-02 9.16e-01
REACTOME EGFR INTERACTS WITH PHOSPHOLIPASE C GAMMA 9 6.89e-01 -7.71e-02 9.16e-01
REACTOME GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION 34 6.89e-01 -3.96e-02 9.16e-01
REACTOME METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION 15 6.89e-01 -5.96e-02 9.16e-01
REACTOME FCERI MEDIATED NF KB ACTIVATION 78 6.90e-01 -2.61e-02 9.16e-01
REACTOME REGULATION OF NPAS4 GENE EXPRESSION 13 6.90e-01 -6.40e-02 9.16e-01
REACTOME LAMININ INTERACTIONS 28 6.91e-01 4.33e-02 9.17e-01
REACTOME INWARDLY RECTIFYING K CHANNELS 35 6.92e-01 3.87e-02 9.17e-01
REACTOME CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY 84 6.93e-01 -2.49e-02 9.17e-01
REACTOME ESTABLISHMENT OF SISTER CHROMATID COHESION 9 6.93e-01 -7.59e-02 9.17e-01
REACTOME SURFACTANT METABOLISM 28 6.95e-01 4.27e-02 9.19e-01
REACTOME FASL CD95L SIGNALING 5 6.96e-01 -1.01e-01 9.19e-01
REACTOME COSTIMULATION BY THE CD28 FAMILY 64 6.97e-01 -2.82e-02 9.19e-01
REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY 14 6.97e-01 6.00e-02 9.19e-01
REACTOME DISEASES OF PROGRAMMED CELL DEATH 96 6.98e-01 -2.29e-02 9.19e-01
REACTOME RHO GTPASES ACTIVATE PAKS 19 6.98e-01 -5.14e-02 9.19e-01
REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS 6 6.99e-01 -9.13e-02 9.19e-01
REACTOME GRB7 EVENTS IN ERBB2 SIGNALING 5 6.99e-01 -1.00e-01 9.19e-01
REACTOME SIGNALING BY NODAL 20 7.00e-01 -4.98e-02 9.19e-01
REACTOME CITRIC ACID CYCLE TCA CYCLE 21 7.02e-01 -4.82e-02 9.19e-01
REACTOME KERATAN SULFATE DEGRADATION 13 7.03e-01 6.11e-02 9.19e-01
REACTOME CLEC7A DECTIN 1 SIGNALING 97 7.03e-01 -2.24e-02 9.19e-01
REACTOME LIPOPHAGY 9 7.03e-01 7.33e-02 9.19e-01
REACTOME TRANSPORT OF SMALL MOLECULES 697 7.04e-01 8.46e-03 9.19e-01
REACTOME REGULATION OF TP53 EXPRESSION AND DEGRADATION 37 7.04e-01 -3.61e-02 9.19e-01
REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES 101 7.04e-01 2.19e-02 9.19e-01
REACTOME OTHER SEMAPHORIN INTERACTIONS 18 7.05e-01 -5.16e-02 9.19e-01
REACTOME FGFR3B LIGAND BINDING AND ACTIVATION 7 7.05e-01 -8.27e-02 9.19e-01
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY 94 7.05e-01 2.26e-02 9.19e-01
REACTOME SUPPRESSION OF APOPTOSIS 7 7.07e-01 8.22e-02 9.20e-01
REACTOME FGFR2 LIGAND BINDING AND ACTIVATION 19 7.07e-01 -4.98e-02 9.20e-01
REACTOME DERMATAN SULFATE BIOSYNTHESIS 10 7.09e-01 -6.81e-02 9.22e-01
REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE 24 7.11e-01 -4.37e-02 9.22e-01
REACTOME MITOCHONDRIAL PROTEIN IMPORT 58 7.11e-01 -2.81e-02 9.22e-01
REACTOME COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES 65 7.11e-01 2.65e-02 9.22e-01
REACTOME VOLTAGE GATED POTASSIUM CHANNELS 42 7.12e-01 -3.29e-02 9.22e-01
REACTOME POST TRANSCRIPTIONAL SILENCING BY SMALL RNAS 7 7.12e-01 -8.05e-02 9.22e-01
REACTOME INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION 21 7.12e-01 4.65e-02 9.22e-01
REACTOME RETROGRADE NEUROTROPHIN SIGNALLING 14 7.14e-01 5.65e-02 9.24e-01
REACTOME RELAXIN RECEPTORS 8 7.16e-01 -7.44e-02 9.24e-01
REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES 34 7.17e-01 3.60e-02 9.24e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2 13 7.17e-01 5.81e-02 9.24e-01
REACTOME G2 PHASE 5 7.18e-01 -9.33e-02 9.24e-01
REACTOME RHOBTB1 GTPASE CYCLE 22 7.18e-01 -4.45e-02 9.24e-01
REACTOME UNWINDING OF DNA 12 7.19e-01 6.01e-02 9.24e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS 9 7.19e-01 6.92e-02 9.24e-01
REACTOME REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS 7 7.19e-01 7.84e-02 9.24e-01
REACTOME INTERLEUKIN 1 SIGNALING 110 7.22e-01 -1.97e-02 9.26e-01
REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS 17 7.22e-01 4.98e-02 9.26e-01
REACTOME PHASE II CONJUGATION OF COMPOUNDS 102 7.22e-01 2.04e-02 9.26e-01
REACTOME DIGESTION OF DIETARY LIPID 7 7.23e-01 7.74e-02 9.26e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR4 14 7.24e-01 -5.45e-02 9.26e-01
REACTOME CROSS PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS PHAGOSOMES 6 7.26e-01 8.27e-02 9.28e-01
REACTOME CDC42 GTPASE CYCLE 144 7.27e-01 1.68e-02 9.29e-01
REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT 236 7.28e-01 1.31e-02 9.30e-01
REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS 21 7.30e-01 -4.36e-02 9.30e-01
REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY 26 7.30e-01 3.91e-02 9.30e-01
REACTOME PEPTIDE HORMONE METABOLISM 84 7.31e-01 2.17e-02 9.30e-01
REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL 58 7.31e-01 2.61e-02 9.30e-01
REACTOME REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION 84 7.32e-01 -2.17e-02 9.30e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION 45 7.32e-01 -2.95e-02 9.30e-01
REACTOME SIGNALING BY ERBB4 57 7.34e-01 -2.61e-02 9.32e-01
REACTOME FATTY ACIDS BOUND TO GPR40 FFAR1 REGULATE INSULIN SECRETION 8 7.36e-01 -6.87e-02 9.34e-01
REACTOME ACYL CHAIN REMODELLING OF PI 17 7.37e-01 4.70e-02 9.34e-01
REACTOME CHREBP ACTIVATES METABOLIC GENE EXPRESSION 8 7.38e-01 -6.82e-02 9.34e-01
REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX 13 7.39e-01 5.35e-02 9.34e-01
REACTOME EUKARYOTIC TRANSLATION ELONGATION 87 7.39e-01 2.07e-02 9.34e-01
REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS 9 7.39e-01 -6.42e-02 9.34e-01
REACTOME NEUROTOXICITY OF CLOSTRIDIUM TOXINS 10 7.40e-01 -6.05e-02 9.34e-01
REACTOME PHOSPHORYLATION OF EMI1 6 7.41e-01 -7.81e-02 9.34e-01
REACTOME ACTIVATION OF BH3 ONLY PROTEINS 30 7.42e-01 3.48e-02 9.34e-01
REACTOME WNT MEDIATED ACTIVATION OF DVL 8 7.42e-01 6.73e-02 9.34e-01
REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES 77 7.42e-01 -2.17e-02 9.34e-01
REACTOME FGFR1C LIGAND BINDING AND ACTIVATION 11 7.43e-01 -5.71e-02 9.35e-01
REACTOME REGULATION OF FZD BY UBIQUITINATION 21 7.44e-01 -4.12e-02 9.35e-01
REACTOME REACTIONS SPECIFIC TO THE COMPLEX N GLYCAN SYNTHESIS PATHWAY 10 7.44e-01 -5.96e-02 9.35e-01
REACTOME E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS 58 7.45e-01 -2.47e-02 9.35e-01
REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES 46 7.46e-01 2.76e-02 9.36e-01
REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION 62 7.46e-01 2.37e-02 9.36e-01
REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS 16 7.49e-01 4.61e-02 9.36e-01
REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS 13 7.50e-01 5.11e-02 9.36e-01
REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX 8 7.50e-01 6.51e-02 9.36e-01
REACTOME ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY 10 7.50e-01 -5.81e-02 9.36e-01
REACTOME COHESIN LOADING ONTO CHROMATIN 8 7.50e-01 -6.50e-02 9.36e-01
REACTOME REGULATION OF NPAS4 GENE TRANSCRIPTION 5 7.50e-01 -8.21e-02 9.36e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING 11 7.52e-01 -5.51e-02 9.36e-01
REACTOME RAF ACTIVATION 33 7.52e-01 -3.18e-02 9.36e-01
REACTOME LGI ADAM INTERACTIONS 14 7.53e-01 -4.87e-02 9.36e-01
REACTOME ACYL CHAIN REMODELLING OF PC 27 7.53e-01 -3.50e-02 9.36e-01
REACTOME O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS 38 7.53e-01 -2.95e-02 9.36e-01
REACTOME MET ACTIVATES PTPN11 5 7.55e-01 8.05e-02 9.37e-01
REACTOME SPERM MOTILITY AND TAXES 9 7.56e-01 -5.99e-02 9.37e-01
REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS 12 7.56e-01 -5.19e-02 9.37e-01
REACTOME BH3 ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI APOPTOTIC BCL 2 MEMBERS 9 7.58e-01 5.94e-02 9.38e-01
REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION 6 7.58e-01 7.26e-02 9.38e-01
REACTOME SYNAPTIC ADHESION LIKE MOLECULES 19 7.58e-01 4.08e-02 9.38e-01
REACTOME DISEASES OF METABOLISM 237 7.59e-01 -1.16e-02 9.38e-01
REACTOME INLA MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS 9 7.60e-01 5.88e-02 9.39e-01
REACTOME GABA RECEPTOR ACTIVATION 57 7.61e-01 2.33e-02 9.39e-01
REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS 8 7.62e-01 -6.20e-02 9.39e-01
REACTOME NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10 12 7.63e-01 -5.03e-02 9.39e-01
REACTOME LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS 19 7.64e-01 -3.98e-02 9.39e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES 16 7.66e-01 -4.30e-02 9.39e-01
REACTOME SEPARATION OF SISTER CHROMATIDS 184 7.67e-01 -1.27e-02 9.39e-01
REACTOME CS DS DEGRADATION 12 7.68e-01 4.92e-02 9.39e-01
REACTOME ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE 9 7.69e-01 5.66e-02 9.39e-01
REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS 23 7.69e-01 3.54e-02 9.39e-01
REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER 77 7.70e-01 -1.93e-02 9.39e-01
REACTOME SIGNALING BY LRP5 MUTANTS 6 7.70e-01 -6.90e-02 9.39e-01
REACTOME CROSSLINKING OF COLLAGEN FIBRILS 16 7.70e-01 4.22e-02 9.39e-01
REACTOME SIGNAL AMPLIFICATION 33 7.71e-01 -2.93e-02 9.39e-01
REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE 37 7.71e-01 2.77e-02 9.39e-01
REACTOME RRNA PROCESSING IN THE MITOCHONDRION 9 7.71e-01 5.61e-02 9.39e-01
REACTOME NONHOMOLOGOUS END JOINING NHEJ 64 7.72e-01 2.10e-02 9.39e-01
REACTOME AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY 8 7.72e-01 5.91e-02 9.39e-01
REACTOME REGULATION OF KIT SIGNALING 16 7.72e-01 4.18e-02 9.39e-01
REACTOME NEUREXINS AND NEUROLIGINS 51 7.73e-01 -2.34e-02 9.39e-01
REACTOME SARS COV 2 TARGETS PDZ PROTEINS IN CELL CELL JUNCTION 5 7.73e-01 -7.45e-02 9.39e-01
REACTOME ION CHANNEL TRANSPORT 172 7.76e-01 -1.26e-02 9.39e-01
REACTOME SODIUM CALCIUM EXCHANGERS 11 7.76e-01 -4.96e-02 9.39e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES 15 7.76e-01 4.25e-02 9.39e-01
REACTOME SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS 14 7.76e-01 -4.39e-02 9.39e-01
REACTOME FORMATION OF PARAXIAL MESODERM 22 7.76e-01 -3.50e-02 9.39e-01
REACTOME SIGNALING BY MST1 5 7.77e-01 -7.30e-02 9.39e-01
REACTOME TELOMERE EXTENSION BY TELOMERASE 22 7.78e-01 -3.47e-02 9.39e-01
REACTOME NETRIN 1 SIGNALING 49 7.78e-01 -2.33e-02 9.39e-01
REACTOME DEFECTIVE CHST3 CAUSES SEDCJD 7 7.78e-01 -6.14e-02 9.39e-01
REACTOME RHO GTPASES ACTIVATE NADPH OXIDASES 21 7.79e-01 3.53e-02 9.39e-01
REACTOME O LINKED GLYCOSYLATION 109 7.79e-01 1.55e-02 9.39e-01
REACTOME RHOU GTPASE CYCLE 37 7.80e-01 2.66e-02 9.39e-01
REACTOME TRYPTOPHAN CATABOLISM 14 7.80e-01 -4.31e-02 9.39e-01
REACTOME ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS 11 7.80e-01 -4.86e-02 9.39e-01
REACTOME POTASSIUM CHANNELS 102 7.81e-01 1.60e-02 9.39e-01
REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS 93 7.81e-01 -1.67e-02 9.39e-01
REACTOME SARS COV 1 HOST INTERACTIONS 92 7.82e-01 1.67e-02 9.39e-01
REACTOME BASIGIN INTERACTIONS 24 7.82e-01 3.26e-02 9.39e-01
REACTOME NTRK2 ACTIVATES RAC1 5 7.83e-01 -7.12e-02 9.39e-01
REACTOME ENDOGENOUS STEROLS 26 7.83e-01 -3.11e-02 9.39e-01
REACTOME THYROXINE BIOSYNTHESIS 10 7.84e-01 -5.00e-02 9.39e-01
REACTOME MULTIFUNCTIONAL ANION EXCHANGERS 9 7.84e-01 5.26e-02 9.39e-01
REACTOME CA2 PATHWAY 62 7.85e-01 -2.00e-02 9.39e-01
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE 105 7.86e-01 1.53e-02 9.39e-01
REACTOME ACYL CHAIN REMODELLING OF PS 22 7.86e-01 -3.34e-02 9.39e-01
REACTOME SMOOTH MUSCLE CONTRACTION 43 7.88e-01 2.37e-02 9.40e-01
REACTOME ION TRANSPORT BY P TYPE ATPASES 51 7.89e-01 2.17e-02 9.40e-01
REACTOME AMYLOID FIBER FORMATION 102 7.89e-01 -1.54e-02 9.40e-01
REACTOME G1 S DNA DAMAGE CHECKPOINTS 67 7.89e-01 -1.89e-02 9.40e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION 27 7.90e-01 -2.97e-02 9.40e-01
REACTOME BETA OXIDATION OF BUTANOYL COA TO ACETYL COA 5 7.91e-01 6.86e-02 9.40e-01
REACTOME DEGRADATION OF DVL 56 7.91e-01 2.05e-02 9.40e-01
REACTOME SLC TRANSPORTER DISORDERS 94 7.91e-01 -1.58e-02 9.40e-01
REACTOME MUCOPOLYSACCHARIDOSES 10 7.92e-01 -4.83e-02 9.40e-01
REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION 145 7.93e-01 -1.26e-02 9.41e-01
REACTOME SELENOAMINO ACID METABOLISM 108 7.94e-01 -1.46e-02 9.41e-01
REACTOME CD28 DEPENDENT VAV1 PATHWAY 11 7.94e-01 -4.54e-02 9.41e-01
REACTOME PHASE 1 INACTIVATION OF FAST NA CHANNELS 6 7.95e-01 -6.12e-02 9.41e-01
REACTOME ERKS ARE INACTIVATED 13 7.96e-01 4.15e-02 9.41e-01
REACTOME POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE 25 7.97e-01 -2.98e-02 9.41e-01
REACTOME ROLE OF ABL IN ROBO SLIT SIGNALING 8 7.97e-01 -5.26e-02 9.41e-01
REACTOME HORMONE LIGAND BINDING RECEPTORS 12 7.98e-01 -4.26e-02 9.42e-01
REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE 30 8.00e-01 2.68e-02 9.42e-01
REACTOME THE NLRP3 INFLAMMASOME 16 8.00e-01 -3.65e-02 9.42e-01
REACTOME BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS 10 8.01e-01 4.60e-02 9.42e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION TERMINATION 30 8.02e-01 -2.65e-02 9.42e-01
REACTOME ERK MAPK TARGETS 20 8.02e-01 -3.24e-02 9.42e-01
REACTOME ACTIVATION OF TRKA RECEPTORS 6 8.02e-01 -5.91e-02 9.42e-01
REACTOME CHYLOMICRON CLEARANCE 5 8.03e-01 6.45e-02 9.42e-01
REACTOME AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA 54 8.03e-01 1.96e-02 9.42e-01
REACTOME COLLAGEN DEGRADATION 61 8.04e-01 -1.84e-02 9.43e-01
REACTOME MET INTERACTS WITH TNS PROTEINS 5 8.05e-01 6.37e-02 9.44e-01
REACTOME RHOBTB2 GTPASE CYCLE 22 8.08e-01 3.00e-02 9.46e-01
REACTOME ACYL CHAIN REMODELING OF CL 5 8.09e-01 6.23e-02 9.47e-01
REACTOME TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE 10 8.13e-01 4.32e-02 9.47e-01
REACTOME SIGNALING BY WNT IN CANCER 32 8.14e-01 -2.41e-02 9.47e-01
REACTOME CELLULAR HEXOSE TRANSPORT 21 8.14e-01 2.97e-02 9.47e-01
REACTOME VITAMIN C ASCORBATE METABOLISM 8 8.14e-01 4.80e-02 9.47e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX IN CANCER 8 8.14e-01 -4.80e-02 9.47e-01
REACTOME OPIOID SIGNALLING 89 8.14e-01 -1.44e-02 9.47e-01
REACTOME LDL CLEARANCE 19 8.15e-01 -3.11e-02 9.47e-01
REACTOME SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE 91 8.15e-01 -1.42e-02 9.47e-01
REACTOME PRE NOTCH PROCESSING IN GOLGI 18 8.15e-01 -3.18e-02 9.47e-01
REACTOME COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING 38 8.15e-01 -2.19e-02 9.47e-01
REACTOME UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN 6 8.17e-01 -5.45e-02 9.49e-01
REACTOME DAG AND IP3 SIGNALING 40 8.18e-01 2.10e-02 9.49e-01
REACTOME POLB DEPENDENT LONG PATCH BASE EXCISION REPAIR 8 8.19e-01 -4.66e-02 9.49e-01
REACTOME PHOSPHORYLATION OF THE APC C 20 8.20e-01 -2.95e-02 9.49e-01
REACTOME SENSORY PERCEPTION OF TASTE 47 8.20e-01 -1.92e-02 9.49e-01
REACTOME SYNTHESIS OF UDP N ACETYL GLUCOSAMINE 7 8.21e-01 4.93e-02 9.50e-01
REACTOME SIALIC ACID METABOLISM 33 8.22e-01 -2.26e-02 9.50e-01
REACTOME SIGNALING BY ROBO RECEPTORS 206 8.22e-01 -9.07e-03 9.50e-01
REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS 9 8.23e-01 4.32e-02 9.50e-01
REACTOME HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS 7 8.24e-01 -4.86e-02 9.50e-01
REACTOME CD22 MEDIATED BCR REGULATION 5 8.24e-01 -5.74e-02 9.50e-01
REACTOME PIWI INTERACTING RNA PIRNA BIOGENESIS 29 8.25e-01 2.37e-02 9.50e-01
REACTOME CA DEPENDENT EVENTS 36 8.25e-01 2.13e-02 9.50e-01
REACTOME UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION 19 8.26e-01 2.91e-02 9.50e-01
REACTOME FGFR3 LIGAND BINDING AND ACTIVATION 12 8.26e-01 -3.66e-02 9.50e-01
REACTOME G PROTEIN BETA GAMMA SIGNALLING 30 8.26e-01 2.31e-02 9.50e-01
REACTOME PROPIONYL COA CATABOLISM 5 8.27e-01 -5.63e-02 9.50e-01
REACTOME VITAMIN B5 PANTOTHENATE METABOLISM 16 8.28e-01 -3.14e-02 9.50e-01
REACTOME CLEC7A INFLAMMASOME PATHWAY 6 8.28e-01 5.11e-02 9.50e-01
REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS 66 8.30e-01 -1.53e-02 9.51e-01
REACTOME ACTIVATION OF MATRIX METALLOPROTEINASES 30 8.32e-01 -2.24e-02 9.52e-01
REACTOME METAL ION SLC TRANSPORTERS 23 8.32e-01 -2.55e-02 9.52e-01
REACTOME THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT 77 8.33e-01 -1.39e-02 9.52e-01
REACTOME REDUCTION OF CYTOSOLIC CA LEVELS 11 8.35e-01 3.63e-02 9.52e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS 9 8.35e-01 -4.01e-02 9.52e-01
REACTOME UPTAKE AND FUNCTION OF ANTHRAX TOXINS 11 8.35e-01 3.62e-02 9.52e-01
REACTOME MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION 15 8.35e-01 -3.10e-02 9.52e-01
REACTOME RHOF GTPASE CYCLE 40 8.36e-01 1.90e-02 9.52e-01
REACTOME CELL CELL JUNCTION ORGANIZATION 64 8.36e-01 1.50e-02 9.52e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES 29 8.36e-01 2.22e-02 9.52e-01
REACTOME DEGRADATION OF GLI1 BY THE PROTEASOME 59 8.38e-01 1.54e-02 9.52e-01
REACTOME SUMOYLATION OF INTRACELLULAR RECEPTORS 29 8.38e-01 2.19e-02 9.53e-01
REACTOME AZATHIOPRINE ADME 22 8.40e-01 -2.49e-02 9.53e-01
REACTOME CRMPS IN SEMA3A SIGNALING 15 8.40e-01 3.01e-02 9.53e-01
REACTOME BETA DEFENSINS 27 8.41e-01 -2.23e-02 9.54e-01
REACTOME ARACHIDONATE PRODUCTION FROM DAG 5 8.43e-01 5.12e-02 9.55e-01
REACTOME DOWNREGULATION OF ERBB4 SIGNALING 9 8.46e-01 3.75e-02 9.57e-01
REACTOME ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS 27 8.46e-01 -2.16e-02 9.57e-01
REACTOME GLUCOCORTICOID BIOSYNTHESIS 10 8.47e-01 3.53e-02 9.57e-01
REACTOME SIGNALING BY FGFR2 IIIA TM 19 8.47e-01 -2.55e-02 9.57e-01
REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 54 8.47e-01 -1.52e-02 9.57e-01
REACTOME NEUTROPHIL DEGRANULATION 460 8.48e-01 5.22e-03 9.57e-01
REACTOME ANDROGEN BIOSYNTHESIS 11 8.51e-01 -3.28e-02 9.57e-01
REACTOME NRAGE SIGNALS DEATH THROUGH JNK 53 8.51e-01 -1.49e-02 9.57e-01
REACTOME CHAPERONE MEDIATED AUTOPHAGY 20 8.51e-01 2.42e-02 9.57e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS 15 8.52e-01 -2.79e-02 9.57e-01
REACTOME VITAMIN B1 THIAMIN METABOLISM 5 8.53e-01 4.78e-02 9.57e-01
REACTOME SYNTHESIS OF PIPS AT THE ER MEMBRANE 5 8.54e-01 4.76e-02 9.57e-01
REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE 17 8.54e-01 -2.58e-02 9.57e-01
REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 73 8.54e-01 -1.24e-02 9.57e-01
REACTOME SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION 8 8.54e-01 3.75e-02 9.57e-01
REACTOME INITIATION OF NUCLEAR ENVELOPE NE REFORMATION 18 8.54e-01 -2.50e-02 9.57e-01
REACTOME RHO GTPASES ACTIVATE CIT 19 8.55e-01 -2.43e-02 9.57e-01
REACTOME KETONE BODY METABOLISM 9 8.55e-01 3.52e-02 9.57e-01
REACTOME METABOLISM OF INGESTED SEMET SEC MESEC INTO H2SE 7 8.56e-01 3.97e-02 9.57e-01
REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS 38 8.56e-01 -1.70e-02 9.57e-01
REACTOME DEPOLYMERISATION OF THE NUCLEAR LAMINA 14 8.57e-01 2.79e-02 9.57e-01
REACTOME SNRNP ASSEMBLY 53 8.58e-01 1.42e-02 9.57e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST 18 8.58e-01 2.43e-02 9.57e-01
REACTOME METABOLISM OF POLYAMINES 56 8.59e-01 -1.37e-02 9.57e-01
REACTOME DISEASES OF MISMATCH REPAIR MMR 5 8.60e-01 4.55e-02 9.58e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD4 15 8.61e-01 2.60e-02 9.58e-01
REACTOME DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15 8 8.62e-01 3.56e-02 9.58e-01
REACTOME TRAFFICKING OF AMPA RECEPTORS 29 8.62e-01 1.87e-02 9.58e-01
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S 53 8.64e-01 1.36e-02 9.59e-01
REACTOME COBALAMIN CBL METABOLISM 7 8.65e-01 3.71e-02 9.59e-01
REACTOME DISEASES OF IMMUNE SYSTEM 29 8.65e-01 -1.83e-02 9.59e-01
REACTOME RESOLUTION OF SISTER CHROMATID COHESION 120 8.65e-01 -8.98e-03 9.59e-01
REACTOME RESPONSE OF MTB TO PHAGOCYTOSIS 22 8.66e-01 2.07e-02 9.59e-01
REACTOME HEDGEHOG OFF STATE 111 8.67e-01 -9.23e-03 9.59e-01
REACTOME P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1 6 8.68e-01 -3.92e-02 9.59e-01
REACTOME DISORDERS OF TRANSMEMBRANE TRANSPORTERS 170 8.68e-01 -7.38e-03 9.59e-01
REACTOME SEMAPHORIN INTERACTIONS 61 8.69e-01 -1.22e-02 9.59e-01
REACTOME RHOQ GTPASE CYCLE 57 8.69e-01 1.26e-02 9.59e-01
REACTOME PI 3K CASCADE FGFR4 19 8.69e-01 -2.18e-02 9.59e-01
REACTOME SUMO IS CONJUGATED TO E1 UBA2 SAE1 5 8.70e-01 4.23e-02 9.59e-01
REACTOME SHC1 EVENTS IN ERBB2 SIGNALING 22 8.71e-01 -2.00e-02 9.59e-01
REACTOME SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA 52 8.72e-01 -1.29e-02 9.59e-01
REACTOME HISTIDINE CATABOLISM 8 8.72e-01 3.28e-02 9.59e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION TERMINATION 23 8.73e-01 -1.93e-02 9.59e-01
REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF 17 8.73e-01 -2.24e-02 9.59e-01
REACTOME FLT3 SIGNALING THROUGH SRC FAMILY KINASES 6 8.74e-01 3.74e-02 9.60e-01
REACTOME GP1B IX V ACTIVATION SIGNALLING 11 8.75e-01 -2.74e-02 9.60e-01
REACTOME INTEGRIN CELL SURFACE INTERACTIONS 83 8.75e-01 -9.98e-03 9.60e-01
REACTOME DEFECTIVE LFNG CAUSES SCDO3 5 8.76e-01 -4.02e-02 9.60e-01
REACTOME NOSTRIN MEDIATED ENOS TRAFFICKING 5 8.77e-01 4.01e-02 9.60e-01
REACTOME CAMK IV MEDIATED PHOSPHORYLATION OF CREB 10 8.78e-01 -2.80e-02 9.61e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE GIP 12 8.78e-01 2.55e-02 9.61e-01
REACTOME MITOTIC SPINDLE CHECKPOINT 109 8.80e-01 8.37e-03 9.61e-01
REACTOME MITOCHONDRIAL TRNA AMINOACYLATION 20 8.81e-01 -1.94e-02 9.61e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1 20 8.81e-01 -1.93e-02 9.61e-01
REACTOME TIGHT JUNCTION INTERACTIONS 29 8.83e-01 1.58e-02 9.61e-01
REACTOME RHOV GTPASE CYCLE 36 8.83e-01 -1.42e-02 9.61e-01
REACTOME MET RECEPTOR ACTIVATION 6 8.83e-01 3.46e-02 9.61e-01
REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX 134 8.84e-01 7.32e-03 9.61e-01
REACTOME FREE FATTY ACIDS REGULATE INSULIN SECRETION 10 8.84e-01 -2.67e-02 9.61e-01
REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS 21 8.84e-01 -1.84e-02 9.61e-01
REACTOME CREATINE METABOLISM 9 8.88e-01 2.71e-02 9.65e-01
REACTOME TRANSLATION 278 8.90e-01 4.82e-03 9.67e-01
REACTOME REGULATION OF SIGNALING BY NODAL 9 8.91e-01 2.65e-02 9.67e-01
REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH 62 8.92e-01 -9.98e-03 9.67e-01
REACTOME SIGNALING BY RETINOIC ACID 41 8.93e-01 1.22e-02 9.67e-01
REACTOME WAX AND PLASMALOGEN BIOSYNTHESIS 5 8.93e-01 3.47e-02 9.67e-01
REACTOME NEUROFASCIN INTERACTIONS 6 8.94e-01 3.13e-02 9.67e-01
REACTOME SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER 15 8.95e-01 -1.97e-02 9.67e-01
REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS 16 8.95e-01 -1.90e-02 9.67e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN 13 8.96e-01 2.10e-02 9.67e-01
REACTOME NEF MEDIATED CD4 DOWN REGULATION 9 8.98e-01 -2.47e-02 9.69e-01
REACTOME CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN 45 9.00e-01 1.08e-02 9.71e-01
REACTOME DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING 61 9.01e-01 9.21e-03 9.71e-01
REACTOME RNA POLYMERASE III CHAIN ELONGATION 18 9.02e-01 1.67e-02 9.72e-01
REACTOME NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY 6 9.03e-01 -2.88e-02 9.72e-01
REACTOME DECTIN 2 FAMILY 26 9.05e-01 1.35e-02 9.74e-01
REACTOME HEME BIOSYNTHESIS 13 9.06e-01 1.89e-02 9.74e-01
REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS 14 9.07e-01 1.81e-02 9.74e-01
REACTOME SARS COV 2 MODULATES AUTOPHAGY 11 9.08e-01 -2.01e-02 9.75e-01
REACTOME CARNITINE METABOLISM 13 9.10e-01 -1.81e-02 9.76e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE 5 9.11e-01 2.90e-02 9.76e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA 25 9.11e-01 -1.30e-02 9.76e-01
REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION 19 9.12e-01 -1.47e-02 9.76e-01
REACTOME REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO 10 9.13e-01 -1.99e-02 9.76e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY DVL INTERACTING PROTEINS 5 9.13e-01 -2.81e-02 9.76e-01
REACTOME ABACAVIR ADME 9 9.14e-01 2.09e-02 9.76e-01
REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS 11 9.14e-01 -1.88e-02 9.76e-01
REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS 39 9.16e-01 9.71e-03 9.78e-01
REACTOME LINOLEIC ACID LA METABOLISM 7 9.19e-01 2.21e-02 9.80e-01
REACTOME TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS 36 9.20e-01 9.69e-03 9.80e-01
REACTOME CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION 11 9.20e-01 -1.74e-02 9.80e-01
REACTOME PI3K EVENTS IN ERBB2 SIGNALING 16 9.20e-01 -1.44e-02 9.80e-01
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY 33 9.21e-01 1.00e-02 9.80e-01
REACTOME DISINHIBITION OF SNARE FORMATION 5 9.21e-01 -2.56e-02 9.80e-01
REACTOME SIGNALING BY MET 78 9.22e-01 -6.39e-03 9.80e-01
REACTOME SIGNALING BY HIPPO 19 9.23e-01 -1.28e-02 9.80e-01
REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT 99 9.24e-01 -5.53e-03 9.81e-01
REACTOME INFECTION WITH MYCOBACTERIUM TUBERCULOSIS 25 9.24e-01 1.10e-02 9.81e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FYN 7 9.25e-01 2.05e-02 9.81e-01
REACTOME TNFR2 NON CANONICAL NF KB PATHWAY 96 9.28e-01 5.37e-03 9.83e-01
REACTOME STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS 10 9.28e-01 -1.65e-02 9.83e-01
REACTOME VASOPRESSIN LIKE RECEPTORS 5 9.29e-01 -2.31e-02 9.83e-01
REACTOME BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA 6 9.29e-01 2.09e-02 9.83e-01
REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR 24 9.30e-01 -1.03e-02 9.83e-01
REACTOME CALCINEURIN ACTIVATES NFAT 9 9.32e-01 -1.63e-02 9.85e-01
REACTOME ERBB2 ACTIVATES PTK6 SIGNALING 13 9.34e-01 -1.32e-02 9.85e-01
REACTOME COMPLEX I BIOGENESIS 49 9.34e-01 6.81e-03 9.85e-01
REACTOME FBXW7 MUTANTS AND NOTCH1 IN CANCER 5 9.35e-01 2.12e-02 9.85e-01
REACTOME ACTIVATION OF RAC1 12 9.35e-01 -1.36e-02 9.85e-01
REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING 30 9.35e-01 -8.55e-03 9.85e-01
REACTOME BETA CATENIN PHOSPHORYLATION CASCADE 16 9.38e-01 1.13e-02 9.86e-01
REACTOME RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES 16 9.39e-01 1.11e-02 9.86e-01
REACTOME FRUCTOSE CATABOLISM 5 9.39e-01 1.97e-02 9.86e-01
REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21 59 9.40e-01 5.70e-03 9.86e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM 38 9.40e-01 -7.10e-03 9.86e-01
REACTOME REGULATED PROTEOLYSIS OF P75NTR 11 9.41e-01 1.29e-02 9.86e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS 8 9.41e-01 -1.50e-02 9.86e-01
REACTOME POLYMERASE SWITCHING 13 9.44e-01 1.13e-02 9.87e-01
REACTOME SUMOYLATION OF IMMUNE RESPONSE PROTEINS 10 9.45e-01 1.27e-02 9.87e-01
REACTOME TRANSPORT OF FATTY ACIDS 8 9.47e-01 -1.36e-02 9.87e-01
REACTOME RETINOID CYCLE DISEASE EVENTS 11 9.47e-01 -1.15e-02 9.87e-01
REACTOME EXTRA NUCLEAR ESTROGEN SIGNALING 74 9.47e-01 -4.45e-03 9.87e-01
REACTOME MHC CLASS II ANTIGEN PRESENTATION 121 9.48e-01 3.46e-03 9.87e-01
REACTOME PHENYLALANINE METABOLISM 6 9.48e-01 -1.53e-02 9.87e-01
REACTOME SYNTHESIS OF 12 EICOSATETRAENOIC ACID DERIVATIVES 7 9.49e-01 1.39e-02 9.87e-01
REACTOME BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA 5 9.50e-01 -1.62e-02 9.87e-01
REACTOME SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL 8 9.50e-01 -1.28e-02 9.87e-01
REACTOME ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN 13 9.50e-01 -1.00e-02 9.87e-01
REACTOME SEMA3A PAK DEPENDENT AXON REPULSION 14 9.50e-01 -9.64e-03 9.87e-01
REACTOME SENSORY PROCESSING OF SOUND 72 9.50e-01 -4.25e-03 9.87e-01
REACTOME HIV TRANSCRIPTION INITIATION 43 9.51e-01 -5.46e-03 9.87e-01
REACTOME LONG TERM POTENTIATION 22 9.51e-01 7.53e-03 9.87e-01
REACTOME MINERALOCORTICOID BIOSYNTHESIS 6 9.53e-01 1.40e-02 9.87e-01
REACTOME PROCESSING AND ACTIVATION OF SUMO 10 9.53e-01 1.08e-02 9.87e-01
REACTOME STAT5 ACTIVATION 7 9.53e-01 -1.27e-02 9.87e-01
REACTOME NCAM1 INTERACTIONS 41 9.54e-01 -5.16e-03 9.87e-01
REACTOME CELL CELL COMMUNICATION 126 9.55e-01 2.92e-03 9.87e-01
REACTOME STABILIZATION OF P53 56 9.55e-01 -4.33e-03 9.87e-01
REACTOME LYSOSPHINGOLIPID AND LPA RECEPTORS 14 9.56e-01 8.59e-03 9.87e-01
REACTOME HEDGEHOG ON STATE 85 9.57e-01 -3.40e-03 9.88e-01
REACTOME TRAIL SIGNALING 8 9.58e-01 -1.07e-02 9.88e-01
REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE 66 9.60e-01 3.61e-03 9.88e-01
REACTOME SIGNALING BY NOTCH4 80 9.60e-01 -3.26e-03 9.88e-01
REACTOME COENZYME A BIOSYNTHESIS 8 9.60e-01 -1.02e-02 9.88e-01
REACTOME METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS 122 9.61e-01 2.56e-03 9.88e-01
REACTOME PHYSIOLOGICAL FACTORS 14 9.62e-01 -7.40e-03 9.88e-01
REACTOME SIGNAL TRANSDUCTION BY L1 20 9.63e-01 -6.03e-03 9.88e-01
REACTOME MITOCHONDRIAL TRANSLATION 93 9.63e-01 -2.78e-03 9.88e-01
REACTOME ABC TRANSPORTER DISORDERS 76 9.63e-01 3.07e-03 9.88e-01
REACTOME TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS 52 9.64e-01 -3.65e-03 9.88e-01
REACTOME PROCESSING OF INTRONLESS PRE MRNAS 19 9.64e-01 6.00e-03 9.88e-01
REACTOME EPHRIN SIGNALING 17 9.65e-01 6.22e-03 9.88e-01
REACTOME ADHERENS JUNCTIONS INTERACTIONS 33 9.65e-01 4.43e-03 9.88e-01
REACTOME ACTIVATION OF PPARGC1A PGC 1ALPHA BY PHOSPHORYLATION 10 9.65e-01 -7.91e-03 9.88e-01
REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY 15 9.66e-01 -6.33e-03 9.88e-01
REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS 18 9.68e-01 5.45e-03 9.89e-01
REACTOME SEMA4D IN SEMAPHORIN SIGNALING 24 9.69e-01 -4.63e-03 9.89e-01
REACTOME PECAM1 INTERACTIONS 12 9.70e-01 -6.24e-03 9.89e-01
REACTOME CELLULAR RESPONSE TO HYPOXIA 74 9.70e-01 -2.51e-03 9.89e-01
REACTOME RRNA MODIFICATION IN THE MITOCHONDRION 6 9.71e-01 8.61e-03 9.89e-01
REACTOME SIGNALING BY INSULIN RECEPTOR 80 9.73e-01 -2.22e-03 9.89e-01
REACTOME INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES 28 9.73e-01 3.69e-03 9.89e-01
REACTOME SYNTHESIS OF KETONE BODIES 8 9.73e-01 -6.89e-03 9.89e-01
REACTOME SYNTHESIS OF 15 EICOSATETRAENOIC ACID DERIVATIVES 6 9.73e-01 -7.94e-03 9.89e-01
REACTOME SARS COV 2 HOST INTERACTIONS 191 9.74e-01 -1.39e-03 9.89e-01
REACTOME DEFECTIVE CHST6 CAUSES MCDC1 8 9.74e-01 -6.61e-03 9.89e-01
REACTOME NEGATIVE REGULATION OF ACTIVITY OF TFAP2 AP 2 FAMILY TRANSCRIPTION FACTORS 10 9.74e-01 5.86e-03 9.89e-01
REACTOME DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE 30 9.74e-01 3.38e-03 9.89e-01
REACTOME DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS 19 9.76e-01 4.04e-03 9.89e-01
REACTOME STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES 16 9.76e-01 4.38e-03 9.89e-01
REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION 16 9.77e-01 4.18e-03 9.90e-01
REACTOME DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1 9 9.78e-01 5.29e-03 9.90e-01
REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE 17 9.79e-01 -3.60e-03 9.90e-01
REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS 15 9.80e-01 3.83e-03 9.90e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH PI3K 7 9.81e-01 5.25e-03 9.91e-01
REACTOME UPTAKE AND ACTIONS OF BACTERIAL TOXINS 28 9.82e-01 2.44e-03 9.92e-01
REACTOME SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS 16 9.84e-01 -2.96e-03 9.92e-01
REACTOME NONSENSE MEDIATED DECAY NMD 107 9.84e-01 1.13e-03 9.92e-01
REACTOME TRAF6 MEDIATED NF KB ACTIVATION 24 9.84e-01 -2.37e-03 9.92e-01
REACTOME APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS 87 9.86e-01 -1.08e-03 9.92e-01
REACTOME SEROTONIN NEUROTRANSMITTER RELEASE CYCLE 17 9.87e-01 -2.34e-03 9.92e-01
REACTOME REGULATION OF NPAS4 MRNA TRANSLATION 9 9.87e-01 3.14e-03 9.92e-01
REACTOME G PROTEIN MEDIATED EVENTS 53 9.87e-01 1.26e-03 9.92e-01
REACTOME CATION COUPLED CHLORIDE COTRANSPORTERS 7 9.88e-01 3.38e-03 9.92e-01
REACTOME RND1 GTPASE CYCLE 41 9.88e-01 -1.39e-03 9.92e-01
REACTOME TRANSPORT AND SYNTHESIS OF PAPS 6 9.90e-01 -2.95e-03 9.93e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS 5 9.90e-01 -3.20e-03 9.93e-01
REACTOME RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY 14 9.91e-01 -1.76e-03 9.93e-01
REACTOME FREE FATTY ACID RECEPTORS 5 9.92e-01 -2.60e-03 9.94e-01
REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION 23 9.95e-01 7.99e-04 9.96e-01
REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK 111 9.95e-01 3.23e-04 9.96e-01
REACTOME PHASE 2 PLATEAU PHASE 14 1.00e+00 -8.44e-05 1.00e+00


Detailed Gene set reports



REACTOME_OLFACTORY_SIGNALING_PATHWAY

REACTOME_OLFACTORY_SIGNALING_PATHWAY
628
set REACTOME_OLFACTORY_SIGNALING_PATHWAY
setSize 348
pANOVA 2.72e-13
s.dist 0.228
p.adjustANOVA 2.83e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
OR8I2 10945
OR52E6 10937
OR56B4 10932
OR52E2 10928
OR2A5 10878
OR8H3 10855
OR2M7 10811
OR5AC2 10808
OR10J3 10801
OR10K2 10779
OR4D5 10765
OR4A47 10758
OR8G5 10756
OR2AT4 10672
OR51G1 10668
OR10P1 10653
OR4C16 10635
OR6C4 10577
OR9K2 10556
OR2T27 10543

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
OR8I2 10945.0
OR52E6 10937.0
OR56B4 10932.0
OR52E2 10928.0
OR2A5 10878.0
OR8H3 10855.0
OR2M7 10811.0
OR5AC2 10808.0
OR10J3 10801.0
OR10K2 10779.0
OR4D5 10765.0
OR4A47 10758.0
OR8G5 10756.0
OR2AT4 10672.0
OR51G1 10668.0
OR10P1 10653.0
OR4C16 10635.0
OR6C4 10577.0
OR9K2 10556.0
OR2T27 10543.0
OR2T3 10510.0
OR4K13 10509.0
OR9A2 10486.0
OR1J1 10480.0
OR5K4 10463.0
OR51E1 10437.0
OR8B12 10436.0
OR52B2 10363.0
OR6K3 10336.0
OR1L1 10335.0
OR2H2 10305.0
OR6N1 10269.0
OR2D2 10268.0
OR56A1 10262.0
OR2S2 10211.0
OR8G1 10210.0
OR51V1 10196.0
OR2T33 10181.0
OR4N2 10128.0
OR8B4 10119.0
OR5M8 10099.0
OR6Y1 10073.0
OR1A1 10066.0
OR2V1 10029.0
OR13A1 10011.0
OR8D1 10000.0
OR52E4 9977.0
OR2V2 9943.0
OR8A1 9941.0
OR10A7 9932.0
OR6F1 9928.0
OR6V1 9925.0
OR10J5 9889.0
OR10G3 9849.0
OR10A4 9842.0
OR1A2 9838.0
OR5AS1 9834.0
OR2G6 9825.0
OR5B2 9807.0
OR5H1 9801.0
OR2B2 9790.0
OR9G4 9754.0
OR51T1 9713.0
OR13J1 9705.0
OR8B8 9632.0
OR10V1 9610.0
OR3A3 9589.0
OR2L3 9551.0
OR6M1 9543.0
OR9A4 9542.0
OR5D16 9533.0
OR14C36 9530.0
OR4D11 9525.0
OR4A16 9485.0
OR5AP2 9448.0
OR10G7 9427.0
OR7A5 9413.0
OR2T1 9408.0
OR51G2 9407.0
OR2B3 9381.0
OR4B1 9379.0
OR2M2 9365.0
OR9Q1 9307.0
OR2C3 9299.0
OR2AG2 9298.0
OR10H2 9227.0
OR7D4 9222.0
OR5A2 9209.0
OR51B4 9203.0
OR2M3 9199.0
OR13C3 9126.0
OR5D18 9117.0
OR6C6 9100.0
OR2Y1 9069.0
OR6B3 9034.0
OR4D2 8978.0
RTP1 8958.0
OR14J1 8935.0
OR2T11 8920.0
OR51F1 8828.0
OR52N2 8776.0
OR5T1 8763.0
OR56A4 8670.0
OR51A2 8578.0
OR10J1 8571.0
OR10Z1 8549.0
OR7C1 8533.0
OR10AD1 8521.0
OR51I2 8516.0
OR4C46 8471.0
OR2AE1 8403.0
OR51E2 8393.0
OR4D6 8314.0
OR1M1 8303.0
OR2L8 8302.0
OR10K1 8180.0
OR5D13 8005.0
OR3A2 8003.0
OR2A12 7898.0
OR5M9 7883.0
OR6K2 7767.0
OR4X1 7732.0
OR4K2 7723.0
OR8K5 7623.0
OR8B2 7596.0
OR4C6 7569.0
OR2K2 7484.0
OR1I1 7475.0
OR2D3 7449.0
OR52K2 7446.0
OR1E1 7413.0
OR8S1 7383.0
OR1L6 7292.0
OR51B2 7212.0
OR5C1 7148.0
OR5AK2 7136.0
OR9I1 7125.0
OR13D1 7069.0
OR51S1 6999.0
OR1B1 6969.0
OR2AG1 6895.0
OR4C45 6823.0
OR4A15 6805.0
OR8H1 6630.0
OR2B11 6491.0
OR4D9 6432.0
OR6C2 6413.0
OR6C3 6366.0
OR51M1 6308.0
OR10G2 6287.0
OR13F1 6241.0
OR2F1 6238.0
OR10H5 6183.0
OR51L1 6140.0
OR52H1 6114.0
OR7G1 6109.0
OR12D3 6038.0
OR2H1 6029.0
OR7A10 5999.0
ANO2 5990.0
OR5A1 5942.0
OR5H6 5780.0
OR14A16 5775.0
OR5M11 5723.0
OR56A3 5721.0
OR4D10 5687.0
OR13G1 5582.0
OR4C3 5448.0
OR6C76 5426.0
OR4L1 5395.0
OR5AR1 5333.0
OR52N1 5305.0
CNGA4 5206.0
OR2AP1 5110.0
OR1D2 5087.0
OR8K1 4969.0
OR56B1 4781.0
OR2L13 4623.0
OR52I2 4592.0
OR7D2 4560.0
OR10A5 4477.0
OR2T6 4442.0
OR4S1 4357.0
OR2AK2 4266.0
OR6B2 4255.0
OR5P2 4251.0
OR10H1 4242.0
OR1C1 4222.0
OR4C15 4121.0
OR5L1 3949.0
OR51B5 3885.0
OR8U8 3875.0
OR52J3 3732.0
OR5T2 3669.0
OR52K1 3478.0
OR4F15 3276.0
OR51F2 3257.0
OR9Q2 3252.0
CNGB1 3235.0
OR51A7 3227.0
OR6A2 3177.0
OR1L8 3148.0
GNB1 3133.0
OR52I1 3126.0
OR5B21 2902.0
GNAL 2572.0
OR6P1 2393.0
OR52D1 2028.0
OR6K6 1677.0
OR5M3 1410.0
OR11A1 1296.0
OR2A14 1006.0
OR2T12 959.0
EBF1 856.0
OR5AU1 581.0
OR1S2 297.0
OR5H2 295.0
OR11G2 162.0
OR1E2 145.0
OR2J2 25.0
OR10X1 -340.0
OR6C65 -505.0
LHX2 -518.0
OR4E2 -590.0
OR7C2 -595.0
OR11H6 -633.0
OR10C1 -883.0
OR56A5 -1074.0
OR8J3 -1240.0
OR11L1 -1348.0
OR4K5 -1418.0
OR7A17 -1529.0
OR6Q1 -1642.0
OR6T1 -1655.0
OR2C1 -1735.0
OR52R1 -1750.0
OR5AN1 -1751.0
OR6C1 -1816.0
OR4F6 -1909.0
OR13C8 -2064.0
OR5D14 -2103.0
OR5K2 -2193.0
OR51I1 -2216.0
OR10A3 -2508.0
ADCY3 -2547.0
OR7E24 -2596.0
OR2M5 -2613.0
OR52L1 -2904.0
OR52A5 -3200.0
OR6S1 -3267.0
OR4A5 -3311.0
OR1N1 -3532.0
OR2T4 -3651.0
OR13C9 -3795.0
OR11H4 -3834.0
OR2Z1 -3846.0
OR6X1 -3998.0
OR4K14 -4377.0
OR4C12 -4474.0
OR8K3 -4528.0
OR5I1 -4798.0
OR7G3 -4841.0
OR13C2 -4917.0
GNG13 -4992.0
OR5B3 -5079.0
LDB1 -5111.0
OR8J1 -5249.0
OR5T3 -5337.0
OR1G1 -5358.0
OR10A2 -5379.0
OR6C70 -5468.0
OR2L2 -5471.0
OR10W1 -5520.0
OR1N2 -5547.0
OR4K1 -5644.0
OR9G1 -5766.5
OR9G9 -5766.5
OR2G3 -5858.0
OR10A6 -5920.0
OR6C74 -6099.0
OR1Q1 -6117.0
OR2L5 -6212.0
OR1L3 -6217.0
OR10G8 -6273.0
OR4M1 -6335.0
RTP2 -6386.0
OR2A2 -6434.0
OR5F1 -6598.0
REEP1 -6662.0
OR8D4 -6755.0
OR3A1 -7092.0
OR5H15 -7115.0
OR10G9 -7171.0
OR52M1 -7370.0
OR2W1 -7500.0
OR4K17 -7656.0
OR7G2 -7688.0
OR10Q1 -7783.0
OR10T2 -7876.0
OR1J2 -7959.0
OR1F1 -7968.0
OR4K15 -8031.0
OR51D1 -8065.0
OR52E8 -8285.0
OR14I1 -8348.0
OR5J2 -8500.0
OR12D2 -8523.0
OR1L4 -8575.0
OR4X2 -8704.0
OR2B6 -8828.0
OR5B12 -8843.0
OR5L2 -8987.0
OR6C75 -9234.0
OR5M1 -9270.0
OR10H4 -9451.0
OR8U3 -9452.0
OR4N5 -9574.0
OR10G4 -9688.0
OR52A1 -9813.0
OR5P3 -9867.0
OR2M4 -9887.0
OR2W3 -9941.0
OR10H3 -9966.0
OR52W1 -10043.0
OR2G2 -10044.0
OR4D1 -10067.0
OR52B6 -10145.0
OR1J4 -10167.0
OR2T8 -10173.0
OR5V1 -10208.0
OR10AG1 -10235.0
OR6B1 -10278.0
OR5K3 -10315.0
OR6C68 -10323.0
OR1S1 -10459.0
OR10S1 -10556.0
OR51B6 -10565.0
OR51Q1 -10612.0
OR8U1 -10651.0
OR5W2 -10652.0
OR5M10 -10700.0
OR1K1 -10848.0
OR8D2 -10855.0
OR5K1 -10856.0
OR13C4 -10873.0
OR2F2 -10989.0
OR6N2 -11010.0
OR5B17 -11029.0


REACTOME_SENSORY_PERCEPTION

REACTOME_SENSORY_PERCEPTION
1581
set REACTOME_SENSORY_PERCEPTION
setSize 555
pANOVA 3.45e-13
s.dist 0.181
p.adjustANOVA 2.83e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
OR8I2 10945
OR52E6 10937
OR56B4 10932
CLPS 10931
OR52E2 10928
AKR1B10 10922
OR2A5 10878
GNGT1 10866
OR8H3 10855
OR2M7 10811
OR5AC2 10808
OR10J3 10801
OR10K2 10779
OR4D5 10765
OR4A47 10758
OR8G5 10756
RBP3 10677
OR2AT4 10672
OR51G1 10668
OR10P1 10653

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
OR8I2 10945.0
OR52E6 10937.0
OR56B4 10932.0
CLPS 10931.0
OR52E2 10928.0
AKR1B10 10922.0
OR2A5 10878.0
GNGT1 10866.0
OR8H3 10855.0
OR2M7 10811.0
OR5AC2 10808.0
OR10J3 10801.0
OR10K2 10779.0
OR4D5 10765.0
OR4A47 10758.0
OR8G5 10756.0
RBP3 10677.0
OR2AT4 10672.0
OR51G1 10668.0
OR10P1 10653.0
OR4C16 10635.0
OR6C4 10577.0
OR9K2 10556.0
APOA4 10551.0
OR2T27 10543.0
OR2T3 10510.0
OR4K13 10509.0
OR9A2 10486.0
OR1J1 10480.0
OR5K4 10463.0
OR51E1 10437.0
OR8B12 10436.0
OR52B2 10363.0
CALHM3 10342.0
OR6K3 10336.0
OR1L1 10335.0
STRC 10316.0
OR2H2 10305.0
AKR1C4 10301.0
RHO 10289.0
OR6N1 10269.0
OR2D2 10268.0
OR56A1 10262.0
TAS2R31 10243.0
OR2S2 10211.0
OR8G1 10210.0
SCN2B 10204.0
OR51V1 10196.0
OR2T33 10181.0
TTR 10144.0
OR4N2 10128.0
OR8B4 10119.0
OR5M8 10099.0
OR6Y1 10073.0
OR1A1 10066.0
APOC3 10060.0
OR2V1 10029.0
OR13A1 10011.0
OR8D1 10000.0
APOM 9983.0
OR52E4 9977.0
OR2V2 9943.0
OR8A1 9941.0
OR10A7 9932.0
OR6F1 9928.0
OR6V1 9925.0
GPIHBP1 9919.0
OR10J5 9889.0
CALHM1 9872.0
OR10G3 9849.0
OR10A4 9842.0
OR1A2 9838.0
OR5AS1 9834.0
OR2G6 9825.0
OR5B2 9807.0
OR5H1 9801.0
OR2B2 9790.0
RPE65 9789.0
OR9G4 9754.0
OR51T1 9713.0
OR13J1 9705.0
OR8B8 9632.0
OR10V1 9610.0
OR3A3 9589.0
OR2L3 9551.0
OR6M1 9543.0
OR9A4 9542.0
OR5D16 9533.0
OR14C36 9530.0
OR4D11 9525.0
OR4A16 9485.0
OR5AP2 9448.0
OR10G7 9427.0
OR7A5 9413.0
OR2T1 9408.0
OR51G2 9407.0
SDR9C7 9394.0
OR2B3 9381.0
OR4B1 9379.0
OR2M2 9365.0
RLBP1 9332.0
OR9Q1 9307.0
OR2C3 9299.0
OR2AG2 9298.0
GUCA1A 9242.0
OR10H2 9227.0
OR7D4 9222.0
OR5A2 9209.0
SAG 9206.0
OR51B4 9203.0
RBP2 9200.0
OR2M3 9199.0
OR13C3 9126.0
OR5D18 9117.0
OR6C6 9100.0
PLB1 9070.0
OR2Y1 9069.0
OR6B3 9034.0
OR4D2 8978.0
HSD17B1 8968.0
RTP1 8958.0
OR14J1 8935.0
OR2T11 8920.0
TAS2R4 8881.0
OR51F1 8828.0
TAS2R40 8826.0
CABP1 8792.0
OR52N2 8776.0
OR5T1 8763.0
APOA1 8719.0
OR56A4 8670.0
LRP2 8644.0
GSN 8629.0
EPB41L1 8607.0
OR51A2 8578.0
OR10J1 8571.0
LRP10 8564.0
OR10Z1 8549.0
OR7C1 8533.0
OR10AD1 8521.0
OR51I2 8516.0
OR4C46 8471.0
OR2AE1 8403.0
OR51E2 8393.0
OR4D6 8314.0
OR1M1 8303.0
OR2L8 8302.0
SCN3A 8264.0
BCO2 8225.0
OR10K1 8180.0
GRXCR1 8166.0
RDH12 8111.0
OR5D13 8005.0
OR3A2 8003.0
SDC4 7989.0
OR2A12 7898.0
OR5M9 7883.0
GRK7 7803.0
OR6K2 7767.0
OR4X1 7732.0
OR4K2 7723.0
CHRNA9 7692.0
TAS2R20 7683.0
TAS2R3 7630.0
OR8K5 7623.0
OR8B2 7596.0
BCO1 7593.0
WHRN 7587.0
OR4C6 7569.0
OR2K2 7484.0
OR1I1 7475.0
OR2D3 7449.0
OR52K2 7446.0
TPRN 7416.0
OR1E1 7413.0
OR8S1 7383.0
GUCY2D 7332.0
OR1L6 7292.0
CDH23 7250.0
GNB3 7220.0
OR51B2 7212.0
STRA6 7160.0
OR5C1 7148.0
OR5AK2 7136.0
OR9I1 7125.0
OR13D1 7069.0
OR51S1 6999.0
RDH8 6990.0
CACNA1D 6984.0
OR1B1 6969.0
OR2AG1 6895.0
OR4C45 6823.0
OR4A15 6805.0
AKR1C1 6671.0
OR8H1 6630.0
OR2B11 6491.0
CIB2 6452.0
OR4D9 6432.0
KCNMB1 6415.0
OR6C2 6413.0
OR6C3 6366.0
OR51M1 6308.0
OR10G2 6287.0
ABCA4 6270.0
OR13F1 6241.0
OR2F1 6238.0
OR10H5 6183.0
USH1C 6173.0
OR51L1 6140.0
OR52H1 6114.0
OR7G1 6109.0
PRKCA 6082.0
MYO3B 6043.0
OR12D3 6038.0
OR2H1 6029.0
CABP2 6015.0
OR7A10 5999.0
ANO2 5990.0
OR5A1 5942.0
OR5H6 5780.0
OR14A16 5775.0
OR5M11 5723.0
OR56A3 5721.0
OR4D10 5687.0
RDH11 5643.0
OR13G1 5582.0
CHRNA10 5580.0
GNAT1 5532.0
OR4C3 5448.0
OR6C76 5426.0
OR4L1 5395.0
OR5AR1 5333.0
OR52N1 5305.0
DHRS9 5286.0
CNGA4 5206.0
AKR1C3 5194.0
OR2AP1 5110.0
SNAP25 5090.0
RDH10 5089.0
OR1D2 5087.0
CTBP2 5075.0
OR8K1 4969.0
RDH16 4868.0
OR56B1 4781.0
CACNB2 4763.0
FNTB 4732.0
OR2L13 4623.0
PDE6A 4619.0
BSN 4609.0
OR52I2 4592.0
OR7D2 4560.0
MYO7A 4512.0
OR10A5 4477.0
OR2T6 4442.0
OR4S1 4357.0
HSPG2 4343.0
APOE 4315.0
OR2AK2 4266.0
OR6B2 4255.0
OR5P2 4251.0
OR10H1 4242.0
OR1C1 4222.0
OR4C15 4121.0
CYP4V2 4118.0
GRK4 4107.0
ESPNL 4009.0
LRP1 4007.0
OR5L1 3949.0
OR51B5 3885.0
OR8U8 3875.0
MYO15A 3762.0
OR52J3 3732.0
OR5T2 3669.0
CACNA2D2 3603.0
PDE6B 3559.0
OR52K1 3478.0
RCVRN 3428.0
TAS1R3 3423.0
OR4F15 3276.0
OR51F2 3257.0
OR9Q2 3252.0
CNGB1 3235.0
OR51A7 3227.0
OR6A2 3177.0
OR1L8 3148.0
GNB1 3133.0
OR52I1 3126.0
ITPR3 3051.0
LDLR 3034.0
SCNN1B 2952.0
APOC2 2945.0
ATP2B1 2938.0
KCNQ4 2929.0
OR5B21 2902.0
CLIC5 2782.0
EZR 2674.0
GNAL 2572.0
OR6P1 2393.0
KCNJ2 2260.0
TAS2R38 2228.0
PLS1 2163.0
OR52D1 2028.0
GPC6 1893.0
ATP2B2 1829.0
KCNMA1 1816.0
OR6K6 1677.0
TAS2R46 1625.0
SDC2 1590.0
OTOF 1576.0
FNTA 1434.0
OR5M3 1410.0
OR11A1 1296.0
TAS2R7 1261.0
SPTBN1 1134.0
SLC24A1 1096.0
APOB 1065.0
OR2A14 1006.0
OR2T12 959.0
SCN4B 954.0
TAS2R8 944.0
CNGA1 890.0
LPL 864.0
EBF1 856.0
TAS2R30 766.0
NMT2 675.0
OR5AU1 581.0
RETSAT 536.0
GRM1 450.0
OR1S2 297.0
OR5H2 295.0
EPB41L3 252.0
DNAJC5 244.0
OR11G2 162.0
TAS1R1 148.0
OR1E2 145.0
HSD17B6 128.0
OR2J2 25.0
OR10X1 -340.0
TRPM5 -407.0
OR6C65 -505.0
LHX2 -518.0
OR4E2 -590.0
OR7C2 -595.0
FSCN2 -610.0
OR11H6 -633.0
OTOGL -775.0
PCLO -872.0
OR10C1 -883.0
PDE6G -921.0
GNB5 -937.0
CALM1 -1041.0
SCNN1A -1072.0
OR56A5 -1074.0
OR8J3 -1240.0
CAPZA1 -1292.0
OR11L1 -1348.0
GNAT3 -1408.0
OR4K5 -1418.0
OR7A17 -1529.0
TRPM4 -1544.0
XIRP2 -1553.0
OR6Q1 -1642.0
OR6T1 -1655.0
RIPOR2 -1692.0
OR2C1 -1735.0
METAP2 -1749.0
OR52R1 -1750.0
OR5AN1 -1751.0
RDX -1802.0
OTOG -1810.0
OR6C1 -1816.0
OR4F6 -1909.0
GRK1 -1954.0
LHFPL5 -1998.0
OR13C8 -2064.0
OR5D14 -2103.0
SLC26A5 -2129.0
TAS2R13 -2162.0
OR5K2 -2193.0
OR51I1 -2216.0
GUCA1C -2238.0
USH1G -2250.0
GPC2 -2311.0
TMC1 -2330.0
OR10A3 -2508.0
RAB3A -2521.0
SCN2A -2546.0
ADCY3 -2547.0
OR7E24 -2596.0
OR2M5 -2613.0
TAS2R10 -2633.0
RGS9BP -2646.0
GPC5 -2838.0
OR52L1 -2904.0
CAMKMT -2963.0
SCN1B -3017.0
OR52A5 -3200.0
TAS2R14 -3250.0
OR6S1 -3267.0
OR4A5 -3311.0
LRP12 -3402.0
OR1N1 -3532.0
OR2T4 -3651.0
OR13C9 -3795.0
OR11H4 -3834.0
OR2Z1 -3846.0
OR6X1 -3998.0
TAS2R39 -4005.0
RDH5 -4076.0
GRXCR2 -4129.0
KCNN2 -4178.0
STX1A -4369.0
OR4K14 -4377.0
PNLIP -4443.0
OR4C12 -4474.0
SCN9A -4494.0
OR8K3 -4528.0
ACTG1 -4615.0
TMIE -4636.0
TWF2 -4701.0
ESPN -4779.0
OR5I1 -4798.0
SDC1 -4818.0
OR7G3 -4841.0
PLCB2 -4884.0
OR13C2 -4917.0
GNG13 -4992.0
SPTAN1 -4993.0
OR5B3 -5079.0
LDB1 -5111.0
GPC1 -5187.0
OR8J1 -5249.0
TAS2R50 -5291.0
OR5T3 -5337.0
OR1G1 -5358.0
OR10A2 -5379.0
OR6C70 -5468.0
OR2L2 -5471.0
TAS1R2 -5499.0
OR10W1 -5520.0
OR1N2 -5547.0
OR4K1 -5644.0
DHRS3 -5684.0
LRP8 -5686.0
OR9G1 -5766.5
OR9G9 -5766.5
TRIOBP -5799.0
AGRN -5809.0
OR2G3 -5858.0
OR10A6 -5920.0
NMT1 -5998.0
LRAT -6073.0
OR6C74 -6099.0
OR1Q1 -6117.0
EPS8 -6131.0
CAPZB -6160.0
OR2L5 -6212.0
OR1L3 -6217.0
OR10G8 -6273.0
SLC17A8 -6282.0
OR4M1 -6335.0
RTP2 -6386.0
TMC2 -6398.0
OR2A2 -6434.0
RBP4 -6512.0
OR5F1 -6598.0
GRM4 -6602.0
PRKCQ -6644.0
REEP1 -6662.0
OR8D4 -6755.0
EPS8L2 -6871.0
LRRC52 -7029.0
OR3A1 -7092.0
OR5H15 -7115.0
OR10G9 -7171.0
OR52M1 -7370.0
TAS2R41 -7475.0
OR2W1 -7500.0
OR4K17 -7656.0
OR7G2 -7688.0
SCNN1G -7705.0
VAMP2 -7723.0
OR10Q1 -7783.0
OR10T2 -7876.0
OR1J2 -7959.0
OR1F1 -7968.0
TAS2R5 -7976.0
OR4K15 -8031.0
OR51D1 -8065.0
MYO3A -8081.0
MYH9 -8128.0
SDC3 -8144.0
PCDH15 -8224.0
OR52E8 -8285.0
OR14I1 -8348.0
SCNN1D -8396.0
OPN1SW -8419.0
METAP1 -8454.0
OR5J2 -8500.0
OR12D2 -8523.0
RBP1 -8536.0
OR1L4 -8575.0
TAS2R16 -8633.0
OR4X2 -8704.0
ACTB -8733.0
MYO1C -8796.0
PJVK -8820.0
OR2B6 -8828.0
OR5B12 -8843.0
OR5L2 -8987.0
TWF1 -9056.0
OR6C75 -9234.0
OR5M1 -9270.0
NAPEPLD -9312.0
OR10H4 -9451.0
OR8U3 -9452.0
GUCA1B -9469.0
OR4N5 -9574.0
TAS2R1 -9591.0
OR10G4 -9688.0
RGS9 -9787.0
OR52A1 -9813.0
OR5P3 -9867.0
OR2M4 -9887.0
OR2W3 -9941.0
OR10H3 -9966.0
OR52W1 -10043.0
OR2G2 -10044.0
OR4D1 -10067.0
TAS2R43 -10086.0
OR52B6 -10145.0
OR1J4 -10167.0
OR2T8 -10173.0
OR5V1 -10208.0
OR10AG1 -10235.0
OR6B1 -10278.0
OR5K3 -10315.0
OR6C68 -10323.0
CAPZA2 -10356.0
OR1S1 -10459.0
OR10S1 -10556.0
OR51B6 -10565.0
OR51Q1 -10612.0
OR8U1 -10651.0
OR5W2 -10652.0
OR5M10 -10700.0
OTOP1 -10806.0
OR1K1 -10848.0
OR8D2 -10855.0
OR5K1 -10856.0
APOA2 -10860.0
OR13C4 -10873.0
OR2F2 -10989.0
OR6N2 -11010.0
OR5B17 -11029.0


REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES

REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES
615
set REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES
setSize 55
pANOVA 3.42e-07
s.dist 0.397
p.adjustANOVA 0.000187



Top enriched genes

Top 20 genes
GeneID Gene Rank
CCL21 10823
CCL27 10790
CXCL11 10704
XCL2 10629
CCL11 10464
CCL2 10462
CCL19 10453
CXCL9 10402
CXCR1 10400
ACKR4 10380
CCL22 10303
CCL7 10251
CXCL5 9649
CCR3 9339
CCL16 9166
CCR10 8995
CXCR5 8864
ACKR3 8779
PF4 8616
CXCL13 8459

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CCL21 10823
CCL27 10790
CXCL11 10704
XCL2 10629
CCL11 10464
CCL2 10462
CCL19 10453
CXCL9 10402
CXCR1 10400
ACKR4 10380
CCL22 10303
CCL7 10251
CXCL5 9649
CCR3 9339
CCL16 9166
CCR10 8995
CXCR5 8864
ACKR3 8779
PF4 8616
CXCL13 8459
CCRL2 8084
CCR4 8006
CXCR2 7444
CX3CL1 7433
XCL1 7425
CCL20 7369
CX3CR1 7009
CCL5 6673
CXCL1 6548
ACKR2 6048
CCR1 5960
XCR1 5759
CXCL16 5754
CCL1 4827
CCR8 3902
CCR5 3473
CCL17 3403
CXCL6 3141
CCL25 2892
PPBP 2850
CCL3 1037
CCR7 1001
CXCR6 818
CXCL8 -3101
CCR2 -3231
CXCL2 -3874
CXCL12 -4284
CXCR4 -4374
CCL28 -4503
CCL13 -5265
CXCL10 -8093
CCR6 -9136
CXCL3 -10102
CCR9 -10511
CCL4 -11032


REACTOME_INTERLEUKIN_12_SIGNALING

REACTOME_INTERLEUKIN_12_SIGNALING
1400
set REACTOME_INTERLEUKIN_12_SIGNALING
setSize 43
pANOVA 1.95e-05
s.dist -0.376
p.adjustANOVA 0.00799



Top enriched genes

Top 20 genes
GeneID Gene Rank
GSTA2 -10633
LCP1 -10158
HNRNPF -10055
HNRNPDL -9764
IFNG -9509
RAP1B -8943
PITPNA -8782
STAT4 -8728
IL12RB2 -8486
ARF1 -8415
JAK2 -8304
PAK2 -7893
JAK1 -7873
GSTO1 -7655
IL10 -7610
ANXA2 -7278
IL12A -6607
TALDO1 -6537
RPLP0 -6181
MTAP -5945

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GSTA2 -10633
LCP1 -10158
HNRNPF -10055
HNRNPDL -9764
IFNG -9509
RAP1B -8943
PITPNA -8782
STAT4 -8728
IL12RB2 -8486
ARF1 -8415
JAK2 -8304
PAK2 -7893
JAK1 -7873
GSTO1 -7655
IL10 -7610
ANXA2 -7278
IL12A -6607
TALDO1 -6537
RPLP0 -6181
MTAP -5945
SERPINB2 -5827
IL12RB1 -5822
TYK2 -5493
IL12B -5296
PPIA -4974
AIP -4876
RALA -4253
PSME2 -4065
MIF -3735
CFL1 -2704
HNRNPA2B1 -1410
CNN2 -1371
CAPZA1 -1292
CDC42 -698
SNRPA1 -401
SOD2 1182
PDCD4 1967
P4HB 3386
LMNB1 4711
SOD1 5985
HSPA9 6756
CA1 6905
TCP1 6937


REACTOME_CELLULAR_RESPONSES_TO_STIMULI

REACTOME_CELLULAR_RESPONSES_TO_STIMULI
1314
set REACTOME_CELLULAR_RESPONSES_TO_STIMULI
setSize 779
pANOVA 2.52e-05
s.dist -0.0887
p.adjustANOVA 0.00827



Top enriched genes

Top 20 genes
GeneID Gene Rank
TUBA3D -10927
H2AC14 -10913
H3C12 -10835
PSMB11 -10777
H2BC14 -10763
RPL39L -10742
IGFBP1 -10628
CCNE1 -10562
CAPZA2 -10356
ERF -10340
CEBPB -10333
KEAP1 -10320
ATF5 -10313
H4C9 -10310
EXOSC4 -10297
HSPA12B -10282
DNAJA2 -10215
MT1M -10169
H2AC20 -10156
TPR -10116

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TUBA3D -10927.0
H2AC14 -10913.0
H3C12 -10835.0
PSMB11 -10777.0
H2BC14 -10763.0
RPL39L -10742.0
IGFBP1 -10628.0
CCNE1 -10562.0
CAPZA2 -10356.0
ERF -10340.0
CEBPB -10333.0
KEAP1 -10320.0
ATF5 -10313.0
H4C9 -10310.0
EXOSC4 -10297.0
HSPA12B -10282.0
DNAJA2 -10215.0
MT1M -10169.0
H2AC20 -10156.0
TPR -10116.0
PTK6 -10083.0
MIR24-2 -10078.0
LAMTOR1 -9994.0
UBE2D2 -9963.0
DEPDC5 -9955.0
H1-5 -9954.0
UBE2S -9950.0
UBB -9922.0
HBA2 -9921.0
H1-4 -9916.0
CCNE2 -9892.0
ATP6V1C1 -9824.0
RPL36 -9806.0
TUBB4A -9800.0
CAPZA3 -9795.0
RPLP2 -9722.0
ASF1A -9714.0
MT1G -9681.0
DNAJB1 -9676.0
MT1A -9621.0
H2BC3 -9544.0
RPL18 -9526.0
EZH2 -9507.0
ELOB -9480.0
SEM1 -9467.0
FZR1 -9437.0
RRAGA -9391.0
MT2A -9361.0
H2BC9 -9300.5
H3C7 -9300.5
MLST8 -9295.0
COX14 -9239.0
LRPPRC -9237.0
TUBB1 -9184.0
FKBP4 -9167.0
GPX8 -9148.0
NUP50 -9137.0
BAG1 -9094.0
EXOSC7 -9084.0
CYBA -9072.0
KPTN -9042.0
SYVN1 -9037.0
NQO1 -9018.0
PGD -8953.0
NFE2L2 -8950.0
TRIM21 -8944.0
ANAPC2 -8906.0
HSF1 -8898.0
TKT -8896.0
BACH1 -8872.0
PSMD14 -8863.0
CAT -8802.0
EXOSC6 -8799.0
RPS9 -8791.0
ATP6V0E1 -8775.0
PPARA -8731.0
H3C1 -8620.0
RPS5 -8592.0
ARFGAP1 -8583.0
MT1X -8541.0
H3C3 -8519.0
ALB -8513.0
RPL13 -8484.0
VCP -8460.0
ETS1 -8439.0
GML -8413.0
H4C16 -8404.0
H2BC21 -8354.0
CBX4 -8266.0
DNAJB11 -8250.0
MT1H -8235.0
MDM2 -8204.0
EIF2AK3 -8186.0
NUP42 -8147.0
VEGFA -8125.0
XPO1 -8068.0
LAMTOR5 -8042.0
WFS1 -8029.0
HSPA1B -7987.0
CLOCK -7986.0
LAMTOR4 -7977.0
PHC1 -7936.0
PPARGC1A -7933.0
DNAJC3 -7905.0
RPL3L -7894.0
CRTC3 -7885.0
CDKN2C -7847.0
KAT5 -7841.0
H4C12 -7830.0
RPA2 -7819.0
COX4I1 -7799.0
MAPKAPK2 -7786.0
MAFG -7773.0
NBN -7749.0
TUBAL3 -7714.0
TXNRD2 -7696.0
PRDX6 -7691.0
ASNS -7677.0
NCOA6 -7664.0
HMGA1 -7648.0
NUP98 -7640.0
RPSA -7578.0
EGLN2 -7544.0
NOTCH1 -7542.0
MAPK3 -7536.0
TINF2 -7527.0
MAPK9 -7465.0
CHD9 -7457.0
CASTOR1 -7453.0
SCO1 -7450.0
NUP62 -7441.0
MAPKAPK5 -7410.0
EXOSC2 -7395.0
MAPK8 -7394.0
WDR24 -7383.0
ETS2 -7342.0
SERP1 -7298.0
KLHDC3 -7268.0
RING1 -7179.0
CCS -7158.0
DCTN5 -7140.0
SRXN1 -7118.0
SEH1L -7114.0
TUBB2B -7059.0
CHAC1 -7041.0
H3-3B -7000.0
PSMD9 -6945.0
NUP160 -6888.0
CLEC1B -6881.0
AGO4 -6874.0
CDK6 -6846.0
PRDX2 -6800.0
CSNK2A2 -6773.0
CDC16 -6705.0
FOS -6648.0
NDC1 -6638.0
RPA1 -6619.0
ATF2 -6615.0
MYC -6612.0
NDUFA4 -6560.0
NUP205 -6549.0
MT3 -6540.0
TALDO1 -6537.0
H1-0 -6533.0
NUP58 -6523.0
PSMB8 -6491.0
PTGES3 -6480.0
RPL18A -6458.0
TBL1XR1 -6448.0
ACTR10 -6431.0
COX8A -6387.0
EP300 -6367.0
ACD -6355.5
RPS10 -6311.0
CAMK2B -6302.0
TUBB2A -6285.0
GSTP1 -6256.0
MIOS -6252.0
SNCB -6224.0
CABIN1 -6215.0
HBA1 -6214.0
MAPKAPK3 -6188.0
RPLP0 -6181.0
CAPZB -6160.0
DNAJB6 -6150.0
NUP37 -6122.0
H2BC15 -6116.0
SIRT1 -6089.0
RPS27L -6070.0
ITFG2 -6041.0
PSMA8 -6030.0
FNIP1 -6001.0
GOSR2 -5914.0
MINK1 -5893.0
RPS27A -5865.0
ANAPC7 -5847.0
SURF1 -5836.0
PSMD13 -5830.0
SSR1 -5781.0
PSME4 -5742.0
HSP90AB1 -5719.0
CTDSP2 -5718.0
RPL26L1 -5690.0
RBX1 -5685.0
RPL37A -5670.0
RPL7A -5630.0
HMOX2 -5559.0
TXNIP -5549.0
H2BC26 -5544.0
DCTN3 -5539.0
SQSTM1 -5484.0
RPL7 -5470.0
AKT1 -5462.0
IL6 -5414.0
PSMD11 -5394.0
ATP6V0E2 -5381.0
RAI1 -5350.0
CDC23 -5346.0
GCLM -5342.0
HSBP1 -5333.0
RRAGC -5327.0
TUBA1B -5322.0
HERPUD1 -5316.0
SLC7A11 -5309.0
TNRC6A -5305.0
NCF4 -5274.0
PSMB3 -5218.0
HSPA2 -5165.0
STAT3 -5158.0
SCO2 -5150.0
FBXL17 -5142.0
NUP210 -5101.0
NPRL3 -5100.0
CSNK2B -5093.0
NUP153 -5090.0
TACO1 -5086.0
UBE2D3 -5052.0
MAPK14 -4997.0
TERF2 -4976.0
GSR -4975.0
GPX5 -4935.0
NUP107 -4906.0
RHEB -4892.0
GFPT1 -4863.0
RPL11 -4856.0
PRDX5 -4847.0
BMI1 -4742.0
TERF2IP -4691.0
CRYAB -4664.0
CDKN2A -4653.0
BLVRA -4627.0
DYNC1I1 -4614.0
NR3C1 -4518.0
COX20 -4501.0
H2AC18 -4497.5
H2AC19 -4497.5
H3C10 -4463.0
SLC46A1 -4429.0
DYNC1LI1 -4424.0
COX19 -4420.0
RPL5 -4410.0
TGS1 -4373.0
LAMTOR2 -4357.0
HSP90B1 -4304.0
MAP3K5 -4292.0
MTF1 -4286.0
H3-3A -4272.0
PSMB5 -4259.0
MT4 -4255.0
RPS29 -4224.0
ERN1 -4220.0
COX7A2L -4201.0
ATP6V1A -4182.0
DNAJC2 -4170.0
DPP3 -4167.0
RPL22L1 -4163.0
H1-1 -4143.0
EXOSC5 -4136.0
HELZ2 -4131.0
TXN2 -4106.0
H2BC12 -4085.0
IMPACT -4081.0
PSME2 -4065.0
RPS16 -4022.0
RPL19 -4018.0
AKT2 -4008.0
SP1 -4003.0
HMOX1 -3970.0
PSMD2 -3966.0
HSPA5 -3955.0
UBC -3937.0
DDX11 -3920.0
BMAL1 -3882.0
PALB2 -3862.0
RAD50 -3822.0
BAG4 -3755.0
ATP6V0C -3747.0
TUBA8 -3728.0
HYOU1 -3706.0
TUBB4B -3663.0
RPS19BP1 -3649.0
RPS14 -3626.0
ATP6V1C2 -3617.0
MEF2D -3575.0
RPL31 -3566.0
MAP1LC3B -3527.0
SOD3 -3515.0
PSMB4 -3508.0
ANAPC5 -3480.0
COX11 -3478.0
JUN -3450.0
SLC38A9 -3401.0
HIF1AN -3398.0
EDEM1 -3353.0
DYNLL1 -3346.0
NUP43 -3319.0
H4C11 -3297.0
MAP2K7 -3285.0
ABCC1 -3260.0
MED1 -3252.0
MIR24-1 -3245.0
LY96 -3240.0
FNIP2 -3145.0
NFKB1 -3133.0
NUP35 -3128.0
CXCL8 -3101.0
RPS6 -3092.0
RPS11 -3081.0
RPL15 -3043.0
UBE2E1 -3038.0
COX6A1 -3025.0
RRAGD -3003.0
H2AZ2 -3002.0
EEF1A1 -2974.0
PSMD5 -2953.0
RPS6KA1 -2943.0
H2AC6 -2934.0
E2F3 -2925.0
PHC3 -2907.0
TNRC6B -2859.0
PSMB7 -2811.0
ZBTB17 -2801.0
PSMC5 -2753.0
H4C1 -2748.0
EXOSC8 -2746.0
HSPB8 -2724.0
BAG2 -2720.0
CDK2 -2703.0
NPRL2 -2668.0
AKT1S1 -2640.0
CITED2 -2612.0
DCTN2 -2604.0
NCOA2 -2571.0
DYNC1I2 -2526.0
DCTN4 -2465.0
HSPA8 -2392.0
PSMD3 -2367.0
WTIP -2328.0
MT1E -2325.0
RPL24 -2291.0
DCP2 -2281.0
MAP2K3 -2274.0
NUP214 -2260.0
CSRP1 -2253.0
UFD1 -2223.0
KHSRP -2098.0
CBX6 -2079.0
RPL3 -2024.0
H4C13 -1989.0
EHMT1 -1982.0
H4C6 -1963.0
TERF1 -1904.0
HIF1A -1895.0
STIP1 -1837.0
PSMD6 -1831.0
NUP93 -1824.0
BMT2 -1812.0
ATR -1803.0
NR1D1 -1776.0
FKBP5 -1759.0
SRPRA -1745.0
EXTL3 -1742.0
RPS21 -1738.0
CDKN1B -1705.0
TLR4 -1666.0
TFDP2 -1654.0
CCNA1 -1611.0
ATP6V1G1 -1591.0
H4C3 -1564.0
HSPB2 -1517.0
KICS2 -1457.0
ANAPC1 -1451.0
HSPA4L -1414.0
RPL30 -1411.0
CRTC1 -1398.0
PSMD7 -1362.0
HIGD1A -1346.0
CAPZA1 -1292.0
RPA3 -1283.0
LAMTOR3 -1274.0
MAPK1 -1262.0
RPL17 -1242.0
ANAPC16 -1202.0
IDH1 -1190.0
ACTR1A -1043.0
MDM4 -1010.0
CARM1 -961.0
RPL10L -952.0
RPL38 -915.0
RPL21 -896.0
RPS28 -888.0
CDC26 -850.0
EP400 -836.0
ATP6V0D1 -823.0
PDIA6 -813.0
RPS8 -801.0
RORA -778.0
KDM6B -760.0
E2F1 -730.0
SESN2 -716.0
MAFK -676.0
HDAC3 -661.0
NUP54 -626.0
GSK3B -613.0
CREBBP -600.0
RLN1 -584.0
SZT2 -565.0
HIKESHI -545.0
HMGA2 -537.0
ID1 -535.0
COX18 -534.0
DYNLL2 -501.0
TCIRG1 -476.0
TUBA1C -435.0
TUBB3 -380.0
PHC2 -374.0
HSPH1 -373.0
NR3C2 -370.0
RPS7 -364.0
ELOC -362.0
RPS3A -293.0
PSMA1 -272.0
TUBA3C -228.0
FLCN -221.0
ATP6V1E1 -208.0
RPL29 -197.0
CREBRF -173.0
MAP4K4 -153.0
EGLN3 -138.0
GRB10 -135.0
CBX2 -124.0
BTRC -91.0
RPL23A -76.0
CSNK2A1 -74.0
PSME1 -45.0
ATP6V1G3 -4.0
TUBA1A 53.0
PSMC2 97.0
EIF2S1 116.0
ERO1A 133.0
H3C11 151.0
PSMD1 215.0
ANAPC11 264.0
EXOSC9 287.0
IGFBP7 289.0
TRIB3 300.0
AKT3 336.0
EXTL2 361.0
HDGF 398.0
E2F2 403.0
CEBPG 449.0
CAMK2G 599.0
RPS6KA2 661.0
HM13 677.0
NUP155 699.0
PSMB6 781.0
RPTOR 783.0
VENTX 900.0
NUDT2 941.0
DYNC1H1 1000.0
YWHAE 1028.0
APOB 1065.0
GSK3A 1163.0
RPL35A 1168.0
SOD2 1182.0
MAP2K6 1198.0
RPL10A 1215.0
EED 1280.0
RPS18 1294.0
HSPA4 1300.0
TNIK 1320.0
NRIP1 1401.0
POM121C 1437.0
SIN3A 1453.0
RPL6 1517.0
MOV10 1527.0
RPL8 1548.0
DCTN6 1583.0
SESN1 1623.0
PSMA7 1653.0
HIF3A 1706.0
PSMA3 1747.0
DIS3 1777.0
WDR59 1862.0
PSMA2 1886.0
HSPA13 1913.0
UBXN7 1920.0
MEF2C 1924.0
NUP188 1951.0
IFNB1 2004.0
TFDP1 2022.0
MAPK10 2096.0
ADD1 2124.0
H4C5 2140.0
PPP1R15A 2162.0
RPS15 2186.0
PARN 2227.0
YIF1A 2254.0
ANAPC4 2282.0
AGO3 2357.0
COX16 2376.0
CDK4 2457.0
RPL27 2466.0
EIF2S2 2480.0
H2AC8 2496.0
CYCS 2521.0
RELA 2577.0
CCNA2 2601.0
RPS25 2614.0
CXXC1 2629.0
H2AC7 2644.5
H2BC7 2644.5
BAG5 2704.0
POM121 2707.0
SEC13 2762.0
ANAPC10 2777.0
EIF2AK1 2778.0
XBP1 2784.0
CDKN1A 2787.0
H2AZ1 2788.0
CREB1 2805.0
ATP6V1H 2807.0
ATF6 2809.0
MAPK11 2820.0
ATM 2903.0
PSMB9 2951.0
NCOA1 2974.0
SEC31A 2983.0
MYDGF 2988.0
SIN3B 3028.0
H4C2 3043.0
ATP6V0B 3049.0
H2BC4 3069.0
FKBP14 3105.0
NCOR2 3341.0
DYNC1LI2 3368.0
RPL36AL 3373.5
P4HB 3386.0
TNFRSF21 3420.0
RNF2 3421.0
H2BC1 3439.0
TXN 3461.0
GCN1 3466.0
PSMA6 3500.0
RPL4 3509.0
EPAS1 3514.0
PGR 3530.0
NCOR1 3553.0
AGO1 3563.0
H2BC10 3582.0
DNAJA1 3626.0
RPS20 3636.0
AAAS 3650.0
COX7C 3686.0
TUBA4B 3701.0
PSMC6 3773.0
ANAPC15 3810.0
EGLN1 3909.0
DNAJB9 3927.0
COX5A 3940.0
EXOSC1 3943.0
CAMK2D 3959.0
HSPA1A 4050.0
NPLOC4 4123.0
POT1 4143.0
ST13 4156.0
RPL41 4173.0
RPL37 4234.0
RANBP2 4244.0
PSME3 4494.0
H4C4 4495.0
TUBA3E 4513.0
ATP6V1F 4516.0
NOX4 4528.0
PLA2G4B 4540.0
RPS24 4577.0
PSMC3 4583.0
GCLC 4593.0
RPS2 4618.0
PPP2R5B 4645.0
H2BC5 4649.0
FAU 4665.0
ATP6V0D2 4710.0
LMNB1 4711.0
H2BC11 4747.0
H2BC13 4779.0
RPL35 4825.0
SHC1 4832.0
RPLP1 4851.0
CUL3 4884.0
EIF2AK4 4894.0
PSMB2 4923.0
CCAR2 4997.0
RPS26 5011.0
USP46 5032.0
FABP1 5069.0
EXTL1 5071.0
CRTC2 5105.0
ATP6V1B1 5127.0
DNAJC7 5143.0
WIPI1 5171.0
CAMK2A 5175.0
ATOX1 5191.0
RPS15A 5197.0
RPL22 5281.0
H4C8 5287.0
TXNRD1 5325.0
RPS27 5348.0
GPX2 5366.0
EHMT2 5380.0
TUBA4A 5381.0
NUP85 5382.0
NFYB 5425.0
STAP2 5433.0
CREB3L4 5469.0
PSMB1 5472.0
HIRA 5494.0
MAP2K4 5503.0
PRKCD 5516.0
CUL1 5560.0
PDIA5 5585.0
MRE11 5638.0
PSMC1 5640.0
CDKN2B 5662.0
ME1 5694.0
KDELR3 5699.0
SMARCD3 5704.0
H2AX 5736.0
PSMD8 5747.0
SKP2 5770.0
DEDD2 5783.0
ATP6V1B2 5796.0
H3C8 5831.0
CREB3L3 5852.0
ATP6V1D 5856.0
ATP6V1G2 5883.0
GPX7 5890.0
SOD1 5985.0
MTOR 5987.0
RPL9 6018.0
VHL 6057.0
HSPB1 6059.0
CALR 6080.0
RBBP4 6098.0
UBE2D1 6123.0
RAE1 6150.0
UBE2C 6168.0
ACADVL 6207.0
COX6C 6211.0
RPS12 6334.0
NPAS2 6355.0
NCF2 6377.0
BAG3 6379.0
EXOSC3 6387.0
TNRC6C 6460.0
CREB3 6482.0
PRDX1 6484.0
PSMB10 6504.0
H2AJ 6509.0
HSP90AA1 6611.0
TUBB6 6645.0
CUL7 6653.0
CREB3L1 6726.0
HSPA9 6756.0
CDKN2D 6758.0
RXRA 6789.0
SUZ12 6827.0
RPL27A 6840.0
TP53 6860.0
RPL12 6871.0
CA9 6918.0
MRPL18 6991.0
SH3BP4 7002.0
SERPINH1 7013.0
RPS3 7019.0
H2BC8 7037.0
UBN1 7058.0
COX6B1 7082.0
PRDX3 7086.0
RPS19 7090.0
PSMA4 7118.0
PSMD4 7146.0
SRPRB 7147.0
GSTA3 7158.0
NFYC 7172.0
H2BC6 7179.0
NUP133 7196.0
GPX1 7211.0
RPL26 7213.0
GPX3 7235.0
RPL13A 7281.5
TLN1 7299.0
H3C4 7300.0
DDIT3 7317.0
LIMD1 7394.0
PSMC4 7533.0
RPL28 7558.0
BLVRB 7594.0
MUL1 7622.0
AQP8 7648.0
CBX8 7655.0
H3C6 7676.0
RPL14 7772.0
H1-2 7807.0
RB1 7828.0
SCMH1 7900.0
CUL2 7902.0
NOX5 7912.0
EPO 7935.0
H1-3 7959.0
RPS13 7996.0
HSPA14 8056.0
SKP1 8064.0
NLRP3 8147.0
GPX6 8249.0
H3C2 8265.0
CDC27 8270.0
CREB3L2 8272.0
LMNA 8304.0
PSMA5 8306.0
COX5B 8356.0
CRYBA4 8451.0
DNAJA4 8512.0
PSMF1 8543.0
HSPA12A 8567.0
RPS23 8609.0
MAPK7 8612.0
UBA52 8631.0
ATF3 8657.0
MBTPS1 8675.0
APOA1 8719.0
MT1F 8755.0
NUP88 8810.0
IL1A 8830.0
BRCA1 8859.0
DCTN1 8905.0
AJUBA 8907.0
RPL34 8944.0
ARNT 8967.0
HSPA1L 8974.0
NFYA 9000.0
MT1B 9125.0
RPL32 9169.0
H3-4 9296.0
H2AC4 9304.0
DCSTAMP 9338.0
GSTA1 9340.0
PSMD12 9475.0
RPL23 9567.0
HSPA6 9679.0
TATDN2 9805.0
TPP1 10038.0
ATF4 10311.0
HBB 10313.0
CCL2 10462.0
ATP6V1E2 10494.0
H2BC17 10609.0
PREB 10783.0
TUBB8 10897.0


REACTOME_INTERLEUKIN_12_FAMILY_SIGNALING

REACTOME_INTERLEUKIN_12_FAMILY_SIGNALING
797
set REACTOME_INTERLEUKIN_12_FAMILY_SIGNALING
setSize 53
pANOVA 4.39e-05
s.dist -0.324
p.adjustANOVA 0.012



Top enriched genes

Top 20 genes
GeneID Gene Rank
GSTA2 -10633
LCP1 -10158
HNRNPF -10055
HNRNPDL -9764
IFNG -9509
RAP1B -8943
PITPNA -8782
STAT4 -8728
IL12RB2 -8486
ARF1 -8415
EBI3 -8344
JAK2 -8304
PAK2 -7893
JAK1 -7873
GSTO1 -7655
IL10 -7610
ANXA2 -7278
IL12A -6607
TALDO1 -6537
RPLP0 -6181

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GSTA2 -10633
LCP1 -10158
HNRNPF -10055
HNRNPDL -9764
IFNG -9509
RAP1B -8943
PITPNA -8782
STAT4 -8728
IL12RB2 -8486
ARF1 -8415
EBI3 -8344
JAK2 -8304
PAK2 -7893
JAK1 -7873
GSTO1 -7655
IL10 -7610
ANXA2 -7278
IL12A -6607
TALDO1 -6537
RPLP0 -6181
MTAP -5945
SERPINB2 -5827
IL12RB1 -5822
TYK2 -5493
STAT1 -5422
IL12B -5296
STAT3 -5158
PPIA -4974
AIP -4876
IL27 -4551
RALA -4253
PSME2 -4065
MIF -3735
CFL1 -2704
CANX -2679
HNRNPA2B1 -1410
CNN2 -1371
CAPZA1 -1292
CDC42 -698
SNRPA1 -401
IL23R 78
IL6ST 144
CRLF1 207
SOD2 1182
PDCD4 1967
P4HB 3386
IL27RA 4541
LMNB1 4711
SOD1 5985
HSPA9 6756
CA1 6905
TCP1 6937
IL23A 9719


REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION
1024
set REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION
setSize 1356
pANOVA 8.23e-05
s.dist -0.0637
p.adjustANOVA 0.0176



Top enriched genes

Top 20 genes
GeneID Gene Rank
PDIA3 -11024
TUBA3D -10927
H2AC14 -10913
B4GAT1 -10906
APOA2 -10860
SPSB2 -10810
TTLL13 -10799
PSMB11 -10777
ETFB -10764
H2BC14 -10763
FBXL12 -10719
CD52 -10691
PMM1 -10680
COPS6 -10675
IGFBP1 -10628
TADA2B -10616
CHML -10599
USP21 -10504
MOGS -10503
ALPI -10500

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PDIA3 -11024.0
TUBA3D -10927.0
H2AC14 -10913.0
B4GAT1 -10906.0
APOA2 -10860.0
SPSB2 -10810.0
TTLL13 -10799.0
PSMB11 -10777.0
ETFB -10764.0
H2BC14 -10763.0
FBXL12 -10719.0
CD52 -10691.0
PMM1 -10680.0
COPS6 -10675.0
IGFBP1 -10628.0
TADA2B -10616.0
CHML -10599.0
USP21 -10504.0
MOGS -10503.0
ALPI -10500.0
CTSZ -10493.0
AXIN2 -10479.0
ARFGAP2 -10468.0
PRSS21 -10450.0
CAPZA2 -10356.0
RNF123 -10351.0
SPP2 -10348.0
INO80D -10346.0
KEAP1 -10320.0
H4C9 -10310.0
EIF5A2 -10273.0
ANKRD9 -10254.0
CNIH2 -10164.0
FBXL4 -10162.0
H2AC20 -10156.0
SPRN -10155.0
ING2 -10117.0
TPR -10116.0
SMURF2 -10094.0
VDAC1 -9974.0
UBE2D2 -9963.0
UBE2S -9950.0
UBB -9922.0
TRAPPC3 -9897.0
MGAT4A -9895.0
GMPPB -9873.0
FEM1B -9812.0
TUBB4A -9800.0
CAPZA3 -9795.0
LY6D -9781.0
MUC15 -9773.0
ADAMTS20 -9758.0
SLC35C1 -9732.0
RCN1 -9706.0
COPS2 -9684.0
TGFB1 -9661.0
MLEC -9627.0
GLB1 -9611.0
MUCL1 -9608.0
H2BC3 -9544.0
GOLGA2 -9498.0
ELOB -9480.0
RAB4B -9478.0
RAB27A -9474.0
SEM1 -9467.0
MATN3 -9439.0
BGLAP -9430.0
RAB22A -9405.0
RRAGA -9391.0
RHOT1 -9347.0
ADAMTS7 -9335.0
FUCA1 -9318.0
H2BC9 -9300.5
MAP3K7 -9289.0
PRMT3 -9268.0
CLSPN -9258.0
FBXW5 -9246.0
TUBB1 -9184.0
RNF5 -9153.0
UBE2H -9141.0
NUP50 -9137.0
SVBP -9126.0
CUL9 -9099.0
KAT2B -9054.0
MAN1A1 -9040.0
SYVN1 -9037.0
LMAN1 -9002.0
VDAC3 -8997.0
B4GALT3 -8983.0
B3GNT3 -8977.0
NFE2L2 -8950.0
MPI -8936.0
SUMF2 -8891.0
SAE1 -8869.0
PSMD14 -8863.0
NUCB1 -8851.0
NEURL2 -8838.0
COMMD3 -8831.0
COMMD8 -8801.0
ACTB -8733.0
PPARA -8731.0
TRIM13 -8721.0
COMMD5 -8720.0
FBXO27 -8707.0
RAB32 -8697.0
SMAD7 -8676.0
RNF146 -8661.0
MYSM1 -8656.0
TADA3 -8645.0
FBXL18 -8644.0
VCPIP1 -8629.0
TMEM115 -8584.0
ARFGAP1 -8583.0
PRND -8569.0
TRIM28 -8551.0
KLHL2 -8546.0
PLET1 -8537.0
COPS7A -8518.0
ALB -8513.0
ZBTB16 -8509.0
TOMM20 -8465.0
H2AC15 -8462.0
VCP -8460.0
PIGS -8453.0
GALNT4 -8431.0
ARF1 -8415.0
H4C16 -8404.0
CD59 -8390.0
RAB11B -8388.0
NOTUM -8371.0
H2BC21 -8354.0
LY6H -8332.0
MUC5B -8314.0
FGA -8302.0
CBX4 -8266.0
ABRAXAS1 -8254.0
FBXL5 -8232.0
SATB1 -8228.0
BIRC2 -8215.0
MDM2 -8204.0
ARF3 -8191.0
FBXO7 -8176.0
USP47 -8157.0
NUP42 -8147.0
GPAA1 -8137.0
PRSS41 -8120.0
GOLGB1 -8114.0
WFS1 -8029.0
DCUN1D1 -8019.0
COPG1 -7998.0
CBX5 -7945.0
HDAC1 -7942.0
PHC1 -7936.0
KDELR2 -7935.0
SIAH2 -7934.0
PPARGC1A -7933.0
PIGT -7927.0
DDA1 -7924.0
NOP58 -7910.0
DNAJC3 -7905.0
JOSD2 -7883.0
CGA -7880.0
TOP1 -7861.0
NANS -7860.0
COPS3 -7855.0
HDAC7 -7845.0
DDB2 -7840.0
DPH3 -7833.0
H4C12 -7830.0
TMEM132A -7827.0
SRD5A3 -7825.0
ULBP2 -7787.0
LRRC41 -7785.0
POMT1 -7774.0
PIGB -7741.0
FBXL7 -7722.0
TUBAL3 -7714.0
USP33 -7710.0
NUP98 -7640.0
NSF -7628.0
PIGV -7605.0
LAMB2 -7601.0
NOD1 -7572.0
AURKB -7569.0
FURIN -7547.0
YKT6 -7534.0
POFUT2 -7523.0
TNIP2 -7469.0
SUDS3 -7460.0
NUP62 -7441.0
TUSC3 -7440.0
MGAT4B -7426.0
RAB24 -7422.0
SCG3 -7376.0
NPL -7373.0
H2AC16 -7367.0
PEX2 -7362.0
SOCS5 -7360.0
SOCS2 -7339.0
GALNT7 -7333.0
STT3A -7307.0
PPARG -7299.0
PIAS2 -7291.0
B3GNT2 -7290.0
TGOLN2 -7281.0
ASB3 -7279.0
USP42 -7230.0
ANKRD28 -7197.0
RCE1 -7189.0
RAB4A -7183.0
RING1 -7179.0
DCTN5 -7140.0
GALNT13 -7127.0
SEH1L -7114.0
USP14 -7091.0
FUOM -7087.0
TUBB2B -7059.0
FN3KRP -7057.0
USP19 -7051.0
MANEA -7046.0
RAB43 -7030.0
PEX5 -7017.0
DOLK -6997.0
DPM1 -6967.0
KLHL3 -6953.0
PSMD9 -6945.0
NUDT14 -6933.0
MUC21 -6914.0
UBE2I -6911.0
NSMCE1 -6906.0
NUP160 -6888.0
MSLN -6829.0
SEC16A -6825.0
ALG12 -6821.0
ADAMTS15 -6809.0
GALNT12 -6808.0
APC -6781.0
GCNT1 -6763.0
SMAD2 -6738.0
COMMD4 -6734.0
CDC34 -6641.0
NDC1 -6638.0
FBXO4 -6630.0
OS9 -6624.0
RPA1 -6619.0
USP20 -6618.0
MYC -6612.0
ENGASE -6601.0
CSNK1D -6584.0
ADAMTS3 -6582.0
BTBD6 -6576.0
NUP205 -6549.0
COG6 -6545.0
RAB1B -6536.0
TRIM4 -6535.0
NUP58 -6523.0
TPST2 -6522.0
FOXL2 -6521.0
MXRA8 -6511.0
PSMB8 -6491.0
NAPA -6443.0
ACTR10 -6431.0
BET1L -6413.0
USO1 -6412.0
RAB6A -6402.0
UGGT1 -6394.0
IZUMO1R -6390.0
RAB12 -6388.0
AGTPBP1 -6382.0
FBXL16 -6380.0
ASB5 -6378.0
CYLD -6369.0
SEC24C -6368.0
EP300 -6367.0
ASXL1 -6340.0
UBE2J2 -6301.0
KBTBD7 -6288.0
TUBB2A -6285.0
AXIN1 -6274.0
KAT2A -6227.0
PLAUR -6208.0
SELENOS -6191.0
FBXO9 -6167.0
CCP110 -6165.0
SEC16B -6161.0
CAPZB -6160.0
STAM2 -6140.0
AGBL1 -6134.0
NUP37 -6122.0
H2BC15 -6116.0
RAB42 -6114.0
DCAF17 -6067.0
ARSI -6040.0
PSMA8 -6030.0
TGFBR2 -6018.0
ACTL6A -6003.0
RABGGTA -5997.0
UBE2F -5984.0
SERPIND1 -5943.0
RNF135 -5931.0
RAD21 -5925.0
PIAS4 -5916.0
GOSR2 -5914.0
RAB33B -5908.0
THBS2 -5906.0
B4GALT6 -5890.0
GALNT8 -5887.0
RPS27A -5865.0
RNF40 -5861.0
MELTF -5848.0
B3GNT4 -5838.0
PSMD13 -5830.0
TTLL10 -5813.0
TNKS -5802.0
ADAMTSL2 -5796.0
FBXW9 -5787.0
SLC35A1 -5780.0
TFG -5746.0
PSME4 -5742.0
JOSD1 -5735.0
RAB27B -5704.0
RBX1 -5685.0
PIAS3 -5675.0
RTF1 -5621.0
UBE2Z -5616.0
TNFAIP3 -5601.0
CD109 -5600.0
PIGO -5598.0
H2BC26 -5544.0
ST8SIA3 -5543.0
UBE2K -5542.0
DCTN3 -5539.0
SAFB -5534.0
UBE2R2 -5527.0
SHISA5 -5509.0
SQSTM1 -5484.0
KCTD7 -5447.0
LYPD4 -5431.0
IL6 -5414.0
PIGQ -5409.0
PSMD11 -5394.0
CALU -5389.0
PIGY -5378.0
SOCS6 -5366.0
INCENP -5364.0
RABGGTB -5341.0
PIGW -5328.0
TUBA1B -5322.0
NAPB -5315.0
LSAMP -5314.0
NRN1L -5308.0
SCFD1 -5284.0
METTL21A -5278.0
BECN1 -5275.0
CSF1 -5233.0
RAB23 -5230.0
PSMB3 -5218.0
COMMD9 -5213.0
KLHL5 -5207.0
STAMBP -5181.0
FBXO30 -5180.0
PPP6R3 -5159.0
NRN1 -5117.0
RAB8B -5112.0
NUP210 -5101.0
CDH2 -5094.0
NUP153 -5090.0
RANGAP1 -5063.0
UBE2D3 -5052.0
COPS4 -5049.0
COG4 -5017.0
SPTAN1 -4993.0
RIPK2 -4991.0
MUC13 -4987.0
CHST8 -4953.0
SEL1L -4949.0
H2AC25 -4934.0
SP3 -4918.0
PPP6R1 -4914.0
NUP107 -4906.0
RPN2 -4904.0
B4GALNT2 -4896.0
ARSJ -4883.0
ADRM1 -4877.0
GFPT1 -4863.0
PIGX -4858.0
GBF1 -4852.0
TMED2 -4822.0
PIGC -4784.0
USP18 -4780.0
FSTL3 -4757.0
L3MBTL2 -4755.0
TFPT -4752.0
THRA -4748.0
TMED10 -4746.0
BMI1 -4742.0
ASB8 -4676.0
COMMD7 -4671.0
MGAT4C -4669.0
KCTD6 -4666.0
RNF168 -4661.0
CDKN2A -4653.0
SPON1 -4648.0
SEC23A -4621.0
DYNC1I1 -4614.0
FBXL15 -4588.0
HLA-A -4587.0
ADAMTS1 -4583.0
PROZ -4572.0
ADAMTS18 -4534.0
BARD1 -4531.0
NR3C1 -4518.0
SPSB3 -4510.0
RUVBL1 -4506.0
H2AC18 -4497.5
H2AC19 -4497.5
FCGR3B -4462.0
MBD5 -4461.0
PCGF2 -4453.0
DYNC1LI1 -4424.0
DCAF5 -4423.0
FBXO6 -4416.0
KTN1 -4390.0
UBE2T -4386.0
ACTR8 -4379.0
ST3GAL1 -4346.0
NEGR1 -4326.0
ASB16 -4318.0
HSP90B1 -4304.0
PML -4271.0
PSMB5 -4259.0
ATXN7 -4219.0
STAG1 -4195.0
VCAN -4185.0
COPS8 -4175.0
DPP3 -4167.0
FBXW4 -4161.0
PRKCSH -4145.0
GATA3 -4127.0
MARCHF6 -4123.0
IDE -4110.0
RNF139 -4104.0
RECK -4101.0
DNMT1 -4094.0
H2BC12 -4085.0
WRN -4082.0
PSME2 -4065.0
TFAP2B -4057.0
RNF103 -4047.0
NR1H3 -3986.0
TRAPPC6B -3967.0
PSMD2 -3966.0
PTEN -3951.0
UBC -3937.0
STAM -3922.0
RAB29 -3916.0
ANO8 -3904.0
FBXW8 -3898.0
RAB1A -3897.0
EEF2 -3889.0
ADAMTS6 -3876.0
ST8SIA6 -3866.0
PALB2 -3862.0
ALG6 -3842.0
KLHL20 -3837.0
EDEM3 -3801.0
USP25 -3793.0
COG7 -3769.0
UHRF2 -3748.0
B3GALNT2 -3740.0
UBXN1 -3734.0
CTBP1 -3732.0
TUBA8 -3728.0
TUBB4B -3663.0
PIGK -3628.0
HGS -3601.0
ADAMTS12 -3592.0
RAET1L -3577.0
OTUD7A -3535.0
PSMB4 -3508.0
GALNT2 -3499.0
RAD23B -3491.0
TNIP3 -3486.0
MGAT1 -3468.0
OTUB1 -3463.0
RAB15 -3433.0
COG8 -3408.0
RAB20 -3405.0
ARFGAP3 -3382.0
DNMT3B -3374.0
KDM1B -3373.0
EDEM1 -3353.0
NFRKB -3352.0
DYNLL1 -3346.0
MFGE8 -3335.0
RAET1G -3321.0
NUP43 -3319.0
WAC -3299.0
H4C11 -3297.0
DNAJC24 -3278.0
KIN -3258.0
B3GLCT -3247.0
GNPNAT1 -3243.0
SENP2 -3226.0
DCUN1D4 -3224.0
OPCML -3221.0
DHDDS -3206.0
FKBP8 -3196.0
COPS7B -3178.0
STX5 -3175.0
IFIH1 -3173.0
USP24 -3132.0
NUP35 -3128.0
RAB18 -3120.0
RTN4RL2 -3116.0
ADAMTS16 -3103.0
RIPK1 -3070.0
B3GNTL1 -3061.0
PIAS1 -3056.0
ST3GAL5 -3042.0
UBE2E1 -3038.0
EEF1A1 -2974.0
CAMKMT -2963.0
PSMD5 -2953.0
RAD52 -2935.0
H2AC6 -2934.0
ARRB2 -2917.0
PHC3 -2907.0
BTBD1 -2884.0
FBXO31 -2880.0
NSMCE4A -2837.0
ALPL -2835.0
GALNT11 -2833.0
TNIP1 -2832.0
HLTF -2828.0
FBXO41 -2815.0
PSMB7 -2811.0
USP34 -2771.0
PEX10 -2767.0
PSMC5 -2753.0
MBD1 -2752.0
H4C1 -2748.0
CTSA -2747.0
USP2 -2718.0
COG2 -2708.0
UBA2 -2695.0
SEC22A -2692.0
TRAPPC10 -2683.0
ALG9 -2682.0
CANX -2679.0
MRTFA -2678.0
TFAP2C -2664.0
TRAF2 -2645.0
ABRAXAS2 -2641.0
B3GNT9 -2638.0
DCTN2 -2604.0
USP13 -2602.0
UAP1 -2599.0
IGFBP5 -2579.0
SATB2 -2575.0
NCOA2 -2571.0
ST8SIA4 -2538.0
DYNC1I2 -2526.0
RAB3A -2521.0
MAT2B -2520.0
ADAMTS19 -2504.0
RAB34 -2490.0
ALG14 -2472.0
SMC5 -2471.0
FEM1C -2466.0
DCTN4 -2465.0
TOP2B -2443.0
HSPA8 -2392.0
IGFBP3 -2391.0
FBXO17 -2375.0
PSMD3 -2367.0
KDELR1 -2337.0
LMO7 -2331.0
ADAMTS14 -2317.0
TTLL7 -2316.0
RWDD3 -2295.0
BLM -2275.0
NUP214 -2260.0
NAE1 -2251.0
UBE2M -2239.0
GAN -2225.0
UFD1 -2223.0
WDR5 -2209.0
MAN1B1 -2190.0
SEC22B -2142.0
RAB5C -2130.0
GFUS -2106.0
ST8SIA1 -2083.0
RAB5A -2060.0
ST6GAL1 -2053.0
FBXL8 -2044.0
BAP1 -2015.0
H4C13 -1989.0
PAF1 -1971.0
NPM1 -1969.0
BCL10 -1966.0
H4C6 -1963.0
ADAMTS9 -1910.0
HIF1A -1895.0
ADAMTS17 -1840.0
PSMD6 -1831.0
THRB -1827.0
NUP93 -1824.0
ASGR2 -1808.0
PIGU -1798.0
NR5A2 -1793.0
COPG2 -1792.0
CKAP4 -1772.0
SCG2 -1767.0
UBE2G2 -1752.0
SPTBN4 -1711.0
EDEM2 -1690.0
GPS1 -1661.0
SOCS3 -1657.0
BST1 -1645.0
PCNA -1619.0
ARSG -1612.0
CCNA1 -1611.0
DAD1 -1605.0
RNF185 -1576.0
H4C3 -1564.0
F7 -1542.0
BABAM1 -1536.0
UBE2N -1518.0
TPGS2 -1511.0
DCAF11 -1475.0
DCAF6 -1471.0
OBSL1 -1465.0
GALNT10 -1455.0
MCRS1 -1432.0
CTR9 -1407.0
KLHL25 -1375.0
PSMD7 -1362.0
SLC17A5 -1345.0
MTA1 -1333.0
AGBL5 -1326.0
H2AC1 -1303.0
CAPZA1 -1292.0
ALG11 -1255.0
XPC -1226.0
HNRNPK -1207.0
SMC3 -1180.0
UBA6 -1148.0
CUL4A -1138.0
C3 -1115.0
FBXW11 -1101.0
C1GALT1 -1093.0
TMED3 -1092.0
ST6GALNAC1 -1088.0
FBN1 -1086.0
LMAN2 -1069.0
ANK3 -1067.0
MUC20 -1061.0
CST3 -1053.0
FOXK1 -1049.0
ACTR1A -1043.0
CALM1 -1041.0
SEC22C -1020.0
DDB1 -1011.0
MDM4 -1010.0
STX17 -1001.0
DPM2 -992.0
COMMD6 -969.0
GORASP1 -965.0
AURKA -949.0
GGCX -948.0
PGM3 -930.0
AFP -858.0
PDIA6 -813.0
LY6K -784.0
TRAPPC9 -779.0
RORA -778.0
KLHL22 -764.0
ARSB -744.0
TRAPPC2L -702.0
CFTR -693.0
TEX101 -692.0
NFKB2 -677.0
USP48 -673.0
RAB38 -652.0
RAB3D -647.0
DPH5 -645.0
TPST1 -643.0
ARF4 -631.0
NUP54 -626.0
TOPORS -614.0
NEU2 -602.0
CREBBP -600.0
NEDD8 -559.0
THSD7B -549.0
DCUN1D2 -517.0
CUL5 -510.0
DYNLL2 -501.0
DCAF4 -491.0
FUT8 -487.0
TTLL6 -478.0
PIGZ -473.0
CDC25A -466.0
DNMT3A -464.0
TUBA1C -435.0
GALNT18 -433.0
PENK -431.0
ST3GAL4 -430.0
VASH1 -408.0
LEO1 -404.0
TUBB3 -380.0
PHC2 -374.0
NR3C2 -370.0
ELOC -362.0
DAG1 -329.0
ARSA -326.0
NGLY1 -309.0
GALNTL6 -308.0
BET1 -305.0
GALNT6 -304.0
USP22 -284.0
PSMA1 -272.0
UBE2G1 -265.0
MBD6 -250.0
RNF152 -244.0
ST3GAL2 -233.0
TUBA3C -228.0
ASB18 -213.0
SBSPON -200.0
FN3K -148.0
USP16 -144.0
MITF -133.0
CBX2 -124.0
RAB5B -122.0
B4GALT4 -120.0
UCHL1 -102.0
NR1H4 -101.0
PMM2 -97.0
AGBL3 -94.0
BTRC -91.0
CNTN3 -81.0
FCSK -66.0
RAD18 -58.0
CCNF -54.0
PSME1 -45.0
F10 -31.0
ALG3 -21.0
OTUB2 -3.0
SP100 30.0
USP37 32.0
YY1 36.0
RAB10 43.0
ST6GAL2 48.0
PIGL 50.0
TUBA1A 53.0
RAB2A 60.0
ASXL2 62.0
TFAP2A 67.0
NEU3 74.0
PSMC2 97.0
COG3 104.0
DOLPP1 105.0
UGGT2 113.0
PIGG 120.0
FEM1A 147.0
TTLL3 150.0
NEU4 171.0
GCNT7 186.0
COG1 193.0
GALNT9 195.0
PSMD1 215.0
ST3GAL6 261.0
MDGA2 276.0
RNF181 282.0
IGFBP7 289.0
STAMBPL1 309.0
RAD23A 349.0
CHST10 354.0
TTLL12 358.0
PNPLA2 397.0
LARGE2 409.0
SMAD1 410.0
APOL1 480.0
KLHL11 488.0
RAB19 498.0
ST8SIA5 524.0
FBXW7 534.0
NTM 537.0
BMP4 570.0
SAR1B 571.0
CNTN5 588.0
METTL22 591.0
TAB1 598.0
COPZ1 615.0
ASB13 622.0
RAB11A 640.0
PARK7 670.0
MCFD2 693.0
NUP155 699.0
HIC1 719.0
PSMB6 781.0
RAB2B 794.0
TGFA 801.0
GOSR1 881.0
CNIH1 891.0
SPSB4 910.0
DTL 932.0
OTUD7B 940.0
FUCA2 979.0
GALNT3 993.0
DCAF13 996.0
DYNC1H1 1000.0
GALNT1 1002.0
NFKBIA 1005.0
TTLL5 1030.0
KLHL9 1033.0
ASB6 1041.0
NSMCE2 1044.0
FBXL14 1045.0
POLB 1048.0
APOB 1065.0
RAB3C 1087.0
NR5A1 1092.0
FAM20C 1111.0
VWA1 1125.0
SPTBN1 1134.0
CHGB 1146.0
MVD 1160.0
ACTR5 1167.0
FGF23 1172.0
SUMO1 1175.0
SMC6 1194.0
TMED7 1203.0
THSD4 1207.0
FBXL19 1224.0
UBA3 1249.0
ALPG 1281.0
COPS5 1293.0
NRIP1 1401.0
CISH 1406.0
PEX13 1418.0
POM121C 1437.0
RTN4RL1 1449.0
SIN3A 1453.0
AMBN 1456.0
ST6GALNAC4 1458.0
ESR1 1465.0
DHPS 1474.0
DAXX 1511.0
THY1 1513.0
MAN2A2 1556.0
FBXO22 1575.0
MUC6 1577.0
DCTN6 1583.0
SDC2 1590.0
PIGP 1645.0
ADAMTS4 1647.0
PSMA7 1653.0
COPB2 1655.0
ADAMTS2 1672.0
BIRC3 1698.0
HIF3A 1706.0
APOA5 1715.0
INO80C 1736.0
HNRNPC 1740.0
PSMA3 1747.0
CD55 1754.0
RFT1 1760.0
NUB1 1775.0
INO80B 1812.0
COP1 1868.0
IL33 1873.0
PSMA2 1886.0
RAB39A 1902.0
UBXN7 1920.0
WDTC1 1926.0
HIPK2 1935.0
PEX14 1942.0
TECTB 1943.0
NUP188 1951.0
PRKN 1954.0
PCSK9 1981.0
LYPD1 1996.0
RAB37 2012.0
MIA3 2013.0
USP15 2016.0
RAB7A 2025.0
LAMB1 2034.0
PARP1 2043.0
RAB8A 2046.0
MUC16 2054.0
ST8SIA2 2061.0
RAB13 2063.0
PIGF 2067.0
BIRC5 2072.0
ALG8 2079.0
TTLL4 2088.0
HDAC4 2095.0
CDC20 2128.0
H4C5 2140.0
FBXO15 2144.0
TRAF6 2148.0
OTOA 2152.0
ASB15 2164.0
GCNT4 2173.0
FBXL22 2177.0
DOHH 2189.0
TRAF3 2206.0
DPH1 2209.0
SPON2 2217.0
POMT2 2221.0
LTBP1 2238.0
TRAPPC5 2253.0
MUC17 2285.0
COPA 2304.0
DCUN1D3 2314.0
XRCC4 2316.0
CDCA8 2329.0
PIGH 2331.0
LMAN2L 2347.0
TOMM70 2355.0
CHST4 2389.0
SENP1 2399.0
SERPINA10 2406.0
RPN1 2407.0
TTLL8 2419.0
POMGNT2 2425.0
FBXL3 2438.0
MDC1 2449.0
ST6GALNAC3 2452.0
NEU1 2462.0
ADAMTS10 2485.0
RAB40B 2495.0
H2AC8 2496.0
GALNT17 2514.0
DCAF7 2517.0
AMFR 2527.0
ALG2 2551.0
ADAMTSL1 2555.0
RELA 2577.0
USP4 2593.0
CCNA2 2601.0
MEN1 2615.0
NOD2 2618.0
NTNG1 2631.0
H2AC7 2644.5
H2BC7 2644.5
GANAB 2663.0
FBXO11 2667.0
KLHL42 2668.0
POM121 2707.0
FBXO21 2719.0
ANK1 2758.0
SEC13 2762.0
MDGA1 2783.0
CDKN1A 2787.0
INO80E 2823.0
TOP2A 2834.0
SEMA5A 2836.0
GFPT2 2852.0
FGG 2888.0
ADAMTS8 2907.0
ST3GAL3 2922.0
MUC12 2939.0
PSMB9 2951.0
GMDS 2957.0
EID3 2961.0
MAN1C1 2973.0
NCOA1 2974.0
SEC31A 2983.0
TP53BP1 2987.0
ASB1 2997.0
NR1H2 3018.0
H2AC21 3029.0
H4C2 3043.0
H2BC4 3069.0
TGFBR1 3076.0
UMOD 3087.0
RAB40C 3113.0
SPTB 3119.0
ZNF131 3129.0
USP28 3139.0
F5 3181.0
UBE2W 3222.0
SEMA5B 3236.0
TULP4 3241.0
TRAPPC4 3246.0
FUT3 3270.0
USP30 3282.0
UBE2E3 3297.0
NCOR2 3341.0
DYNC1LI2 3368.0
MGAT2 3373.5
P4HB 3386.0
RNF2 3421.0
DDOST 3433.0
H2BC1 3439.0
UBE2B 3450.0
SMAD3 3457.0
PROS1 3463.0
ASB7 3499.0
PSMA6 3500.0
UCHL3 3504.0
EPAS1 3514.0
MAN2A1 3517.0
PTRH2 3524.0
PGR 3530.0
VASH2 3542.0
LHB 3546.0
H2BC10 3582.0
SMAD4 3622.0
THBS1 3638.0
AAAS 3650.0
LAMC1 3659.0
SUMF1 3670.0
PPP6C 3691.0
HDAC2 3695.0
TUBA4B 3701.0
USP7 3746.0
PSMC6 3773.0
USP10 3782.0
THSD1 3783.0
UBE2L3 3798.0
VNN2 3808.0
WSB1 3881.0
ERCC8 3888.0
POMK 3932.0
UBE2V2 3951.0
ART4 3985.0
CDC73 4018.0
VGF 4029.0
NUS1 4037.0
GMPPA 4066.0
COPB1 4104.0
B3GNT7 4112.0
SSPOP 4114.0
SPSB1 4117.0
NPLOC4 4123.0
ANK2 4177.0
H2AC13 4182.0
AMDHD2 4185.0
TPGS1 4191.0
RHOA 4216.0
RANBP2 4244.0
NTNG2 4250.0
UIMC1 4260.0
TRIM25 4288.0
DPH7 4293.0
USP12 4295.0
APOE 4315.0
BABAM2 4327.0
FBXO32 4332.0
RBBP5 4358.0
EEF2KMT 4424.0
POMGNT1 4463.0
B3GNT8 4468.0
LYPD3 4488.0
ADAM10 4490.0
PSME3 4494.0
H4C4 4495.0
DPM3 4505.0
TUBA3E 4513.0
FBXL13 4520.0
DERL1 4531.0
SENP8 4543.0
CEACAM5 4544.0
FBXW2 4554.0
DDX5 4556.0
ATXN3 4557.0
FN1 4581.0
PSMC3 4583.0
RPS2 4618.0
SPTBN2 4620.0
KLHL21 4627.0
FOXK2 4644.0
H2BC5 4649.0
TECTA 4654.0
CNTN4 4679.0
FBXL20 4689.0
RAB14 4706.0
ALG5 4720.0
H2BC11 4747.0
INO80 4751.0
H2BC13 4779.0
USP3 4788.0
CDK1 4811.0
TRAPPC1 4877.0
NICN1 4882.0
CUL3 4884.0
SEC24A 4899.0
AGBL4 4920.0
PSMB2 4923.0
TDG 4948.0
GNE 4958.0
PTP4A2 4993.0
TNKS2 5009.0
F2 5015.0
CMAS 5030.0
SUMO2 5053.0
EVA1A 5057.0
ETFBKMT 5117.0
ZRANB1 5156.0
B4GALT2 5177.0
WDR48 5225.0
USP44 5246.0
COL7A1 5280.0
SHPRH 5282.0
RNF144A 5284.0
H4C8 5287.0
NR2C1 5298.0
DDX17 5309.0
TUBA4A 5381.0
NUP85 5382.0
FBXO2 5403.0
TBC1D20 5412.0
COG5 5415.0
NR4A2 5428.0
DCAF10 5445.0
LRR1 5446.0
PSMB1 5472.0
TRIM27 5508.0
PRSS23 5517.0
TRRAP 5543.0
CUL1 5560.0
OTULIN 5576.0
QSOX1 5583.0
DMP1 5608.0
LARGE1 5612.0
PSMC1 5640.0
ADRB2 5673.0
RAB35 5675.0
KDELR3 5699.0
USP8 5722.0
PUM2 5729.0
PSMD8 5747.0
ART3 5766.0
SKP2 5770.0
ADAMTSL5 5810.0
ADAMTS13 5829.0
PIGM 5838.0
YOD1 5841.0
ARF5 5843.0
EIF5A 5880.0
NANP 5887.0
RAB3B 5913.0
KLHL41 5916.0
CNIH3 5955.0
RAB44 5981.0
RAB26 6025.0
VDAC2 6034.0
MUC4 6036.0
TMEM129 6041.0
VHL 6057.0
CALR 6080.0
PGAP1 6101.0
UBE2D1 6123.0
RAE1 6150.0
MUC3A 6158.0
UBE2C 6168.0
GALNT16 6182.0
DERL2 6213.0
EEF1AKMT2 6221.0
GALNT14 6232.0
USP49 6242.0
SPTBN5 6254.0
CCN1 6292.0
THSD7A 6293.0
MAN1A2 6317.0
DCAF16 6319.0
CTSC 6371.0
DPAGT1 6384.0
C4A 6423.5
CP 6449.0
DCAF8 6501.0
PSMB10 6504.0
ARCN1 6528.0
AMTN 6569.0
TTLL11 6586.0
COPE 6589.0
USP5 6594.0
TUBB6 6645.0
RAB31 6650.0
CUL7 6653.0
SERPINC1 6680.0
STC2 6699.0
B4GALT5 6730.0
COMMD1 6737.0
DCUN1D5 6745.0
RXRA 6789.0
ASB17 6818.0
SUZ12 6827.0
TP53 6860.0
ALG1 6907.0
MAVS 6952.0
CAND1 6954.0
APP 6979.0
PIGN 6980.0
ADAMTSL4 6995.0
HERC2 7015.0
H2BC8 7037.0
ENAM 7077.0
ST6GALNAC5 7097.0
RAB30 7111.0
IGFBP4 7115.0
PSMA4 7118.0
PSMD4 7146.0
FPGT 7170.0
H2BC6 7179.0
NUP133 7196.0
INS 7226.0
SEC24D 7233.0
SPTA1 7266.0
SPP1 7276.0
VCPKMT 7278.0
RAB21 7376.0
RNF20 7395.0
PRKDC 7397.0
SUMO3 7428.0
SEC24B 7429.0
CEACAM7 7507.0
ST6GALNAC2 7524.0
PSMC4 7533.0
GALNTL5 7537.0
TTL 7542.0
MGAT3 7551.0
BPIFB2 7600.0
FBXO44 7620.0
MUL1 7622.0
CBX8 7655.0
TNC 7661.0
PEX12 7703.0
COPZ2 7707.0
ASB14 7728.0
CCDC8 7742.0
ITIH2 7751.0
EEF1AKMT1 7782.0
CPM 7818.0
ARRB1 7821.0
ICMT 7827.0
MIA2 7869.0
ST6GALNAC6 7875.0
OTUD3 7884.0
LRRC49 7896.0
SCMH1 7900.0
CUL2 7902.0
RAB6B 7918.0
LYPD5 7952.0
RARA 7975.0
UBE2Q2 8044.0
ASB4 8048.0
UCHL5 8055.0
SKP1 8064.0
NAGK 8067.0
SERPINA1 8077.0
VNN1 8145.0
NLRP3 8147.0
H2AC11 8172.0
ADAMTSL3 8181.0
MPDU1 8182.0
FOLR1 8186.0
SEC23IP 8203.0
TTLL1 8210.0
DPH6 8212.0
RNF7 8213.0
APLP2 8239.0
TMED9 8275.0
PSMA5 8306.0
GRIA1 8377.0
VDR 8386.0
B4GALT1 8397.0
ARSK 8404.0
RIGI 8418.0
NAPG 8441.0
WSB2 8442.0
ZNF350 8456.0
RAB36 8481.0
AGBL2 8514.0
IKBKE 8536.0
PSMF1 8543.0
SPACA4 8551.0
NSMCE3 8579.0
ASB2 8611.0
COMMD10 8627.0
HRC 8628.0
UBA52 8631.0
LY6E 8638.0
SENP5 8658.0
MBTPS1 8675.0
COMMD2 8693.0
SNX3 8718.0
APOA1 8719.0
MUC7 8721.0
MGAT5 8767.0
MUC1 8790.0
NUP88 8810.0
PROC 8816.0
FAM20A 8832.0
WDR20 8855.0
BRCA1 8859.0
RAB25 8889.0
ASB10 8897.0
DCTN1 8905.0
TF 8917.0
KBTBD8 8936.0
ASGR1 8952.0
GOLM1 8983.0
DPH2 8994.0
GALNT15 9025.0
LYPD6B 9026.0
SKIC8 9045.0
TAF10 9057.0
ADAMTS5 9105.0
B3GNT6 9107.0
FBXO10 9149.0
GCNT3 9153.0
GALNT5 9231.0
KNG1 9260.0
ALG10 9293.0
H2AC4 9304.0
FBXW10 9318.0
TTLL9 9320.0
FSTL1 9327.0
FOLR2 9376.0
LMAN1L 9380.0
LY6G6D 9395.0
CHD3 9403.0
LYPD2 9412.0
PSCA 9420.0
PSMD12 9475.0
ALG10B 9478.0
LY6G6C 9482.0
GP2 9509.0
TTLL2 9517.0
RAB17 9550.0
H2AC12 9576.0
MEPE 9583.0
FBXO40 9599.0
KBTBD6 9645.0
SPARCL1 9668.0
B3GNT5 9831.0
NR1I2 9878.0
AHSG 9909.0
GPIHBP1 9919.0
GPLD1 10018.0
TRAPPC6A 10047.0
A4GNT 10351.0
LGALS1 10407.0
FBXW12 10457.0
AREG 10515.0
MUC5AC 10555.0
H2AC17 10569.0
H2BC17 10609.0
UBD 10683.0
PREB 10783.0
TUBB8 10897.0
LYPD8 10954.0


REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM

REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM
78
set REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM
setSize 688
pANOVA 8.69e-05
s.dist -0.0878
p.adjustANOVA 0.0176



Top enriched genes

Top 20 genes
GeneID Gene Rank
CCL4 -11032
IFNL1 -10945
PTPN18 -10861
H3C12 -10835
IFITM2 -10828
BST2 -10781
PSMB11 -10777
CSH1 -10709
IL7R -10665
GSTA2 -10633
IL4 -10621
IFI35 -10615
HLA-F -10607
TNFRSF12A -10540
NRAS -10476
IFNL2 -10444
MCL1 -10433
RORC -10429
UBA7 -10332
LTBR -10330

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CCL4 -11032.0
IFNL1 -10945.0
PTPN18 -10861.0
H3C12 -10835.0
IFITM2 -10828.0
BST2 -10781.0
PSMB11 -10777.0
CSH1 -10709.0
IL7R -10665.0
GSTA2 -10633.0
IL4 -10621.0
IFI35 -10615.0
HLA-F -10607.0
TNFRSF12A -10540.0
NRAS -10476.0
IFNL2 -10444.0
MCL1 -10433.0
RORC -10429.0
UBA7 -10332.0
LTBR -10330.0
IFNA5 -10314.0
TNFRSF25 -10196.0
LCP1 -10158.0
IL32 -10135.0
IL22RA1 -10134.0
TPR -10116.0
IFNA1 -10080.0
AGER -10061.0
HNRNPF -10055.0
STAT5B -10050.0
PTPN12 -10007.0
BATF -10006.0
IFNA21 -9991.0
UBE2D2 -9963.0
UBB -9922.0
DUSP7 -9909.0
INPPL1 -9908.0
IL5RA -9902.0
PLCG1 -9896.0
CASP3 -9798.0
HNRNPDL -9764.0
TGFB1 -9661.0
CEBPD -9648.0
PPM1B -9560.0
GRAP2 -9541.0
SIGIRR -9529.0
IL13 -9522.0
IRF7 -9515.0
IFNG -9509.0
ELOB -9480.0
SEM1 -9467.0
CNTFR -9421.0
MMP1 -9420.0
MT2A -9361.0
H3C7 -9300.5
MAP3K7 -9289.0
HLA-B -9281.0
IL22 -9261.0
IKBIP -9225.0
IL10RB -9193.0
IL17RB -9165.0
NUP50 -9137.0
IL2RB -9107.0
EIF4E2 -9017.0
TRIM21 -8944.0
RAP1B -8943.0
TNFSF13 -8924.0
PSMD14 -8863.0
IRF6 -8858.0
ANXA1 -8847.0
PIN1 -8800.0
SYK -8792.0
PITPNA -8782.0
IRF1 -8752.0
STAT4 -8728.0
SMAD7 -8676.0
H3C1 -8620.0
H3C3 -8519.0
IL12RB2 -8486.0
ARF1 -8415.0
LRRC14 -8374.0
IL36G -8373.0
EBI3 -8344.0
OAS3 -8307.0
JAK2 -8304.0
ALOX15 -8294.0
PTPN9 -8284.0
RAPGEF1 -8244.0
BIRC2 -8215.0
GBP6 -8169.0
NUP42 -8147.0
VEGFA -8125.0
PRKACA -8098.0
IRAK3 -8095.0
CXCL10 -8093.0
IFNA2 -8022.0
CASP1 -7993.0
KRAS -7961.0
PAK2 -7893.0
B2M -7892.0
JAK1 -7873.0
HLA-E -7859.0
YWHAZ -7837.0
CRKL -7832.0
ITGB1 -7812.0
MAPKAPK2 -7786.0
RAG2 -7754.0
IRF3 -7750.0
HRAS -7726.0
VAMP2 -7723.0
GSTO1 -7655.0
NUP98 -7640.0
IL10 -7610.0
TNFSF14 -7585.0
NOD1 -7572.0
MAPK3 -7536.0
TNIP2 -7469.0
MAPK9 -7465.0
NUP62 -7441.0
YES1 -7425.0
PIM1 -7402.0
MAPK8 -7394.0
HAVCR2 -7391.0
SOCS5 -7360.0
SOCS2 -7339.0
EDARADD -7287.0
ANXA2 -7278.0
TNFRSF1B -7271.0
HGF -7168.0
IL9 -7148.0
ARIH1 -7136.0
PELI3 -7120.0
SEH1L -7114.0
RPS6KA5 -7113.0
LGALS9 -7112.0
USP14 -7091.0
IL21 -7053.0
PSMD9 -6945.0
NUP160 -6888.0
SOCS1 -6887.0
EIF4E -6843.0
TRIM29 -6799.0
CNTF -6775.0
IL4R -6670.0
FOS -6648.0
IRS2 -6645.0
NDC1 -6638.0
IFNA6 -6637.0
PPP2CA -6627.0
ATF2 -6615.0
MYC -6612.0
IL12A -6607.0
ICAM1 -6591.0
JUNB -6577.0
MMP9 -6570.0
NUP205 -6549.0
TALDO1 -6537.0
NUP58 -6523.0
IFNGR1 -6516.0
PSMB8 -6491.0
KPNA5 -6485.0
IL19 -6439.0
IFIT2 -6317.0
IFNAR2 -6312.0
ITGB2 -6310.0
S1PR1 -6304.0
CAMK2B -6302.0
IL17RE -6279.0
NKIRAS1 -6228.0
MAPKAPK3 -6188.0
RPLP0 -6181.0
NUP37 -6122.0
PLCG2 -6119.0
CD70 -6078.0
CRK -6052.0
PSMA8 -6030.0
MAP3K14 -5999.0
XAF1 -5969.0
PRTN3 -5965.0
MTAP -5945.0
TRIM31 -5942.0
IL2RA -5866.0
RPS27A -5865.0
CCND1 -5842.0
PSMD13 -5830.0
SERPINB2 -5827.0
IL12RB1 -5822.0
KPNA1 -5788.0
PELI2 -5752.0
PTPN6 -5744.0
PSME4 -5742.0
RBX1 -5685.0
BCL2L1 -5668.0
PTGS2 -5664.0
F13A1 -5595.0
RSAD2 -5593.0
LTA -5584.0
EIF2AK2 -5557.0
NFKBIB -5528.0
TYK2 -5493.0
IRF9 -5491.0
SQSTM1 -5484.0
AKT1 -5462.0
STAT1 -5422.0
IL6 -5414.0
PSMD11 -5394.0
GBP4 -5380.0
TRIM34 -5372.0
SOCS6 -5366.0
HLA-DQA1 -5354.0
IL12B -5296.0
HLA-DRB1 -5279.0
MX1 -5271.0
PTPN4 -5241.0
CD4 -5234.0
CSF1 -5233.0
PSMB3 -5218.0
GRB2 -5215.0
JAK3 -5160.0
STAT3 -5158.0
NUP210 -5101.0
TRIM22 -5095.0
NUP153 -5090.0
UBE2L6 -5084.0
UBE2D3 -5052.0
MAPK14 -4997.0
RIPK2 -4991.0
PPIA -4974.0
NUP107 -4906.0
KPNA4 -4881.0
IL15RA -4880.0
AIP -4876.0
PIK3R1 -4826.0
SDC1 -4818.0
FLT3LG -4783.0
USP18 -4780.0
IKBKB -4657.0
HLA-A -4587.0
PIK3CD -4566.0
IL27 -4551.0
DUSP3 -4516.0
PTPN23 -4491.0
PIK3CA -4471.0
H3C10 -4463.0
BRWD1 -4435.0
LYN -4414.0
ZEB1 -4371.0
STX1A -4369.0
PTPN2 -4333.0
HSP90B1 -4304.0
PML -4271.0
PSMB5 -4259.0
RALA -4253.0
TNFRSF8 -4247.0
CHUK -4148.0
GATA3 -4127.0
PSME2 -4065.0
AKT2 -4008.0
HMOX1 -3970.0
PSMD2 -3966.0
UBC -3937.0
CXCL2 -3874.0
PTPRZ1 -3819.0
MIF -3735.0
MEF2A -3731.0
TWIST1 -3719.0
IL20RA -3713.0
IL17RA -3660.0
RELB -3646.0
PPP2R5D -3640.0
IL6R -3631.0
CSK -3531.0
PSMB4 -3508.0
TIFA -3462.0
JUN -3450.0
IFNLR1 -3445.0
HMGB1 -3434.0
MAP3K3 -3356.0
NLRC5 -3345.0
PIK3R2 -3341.0
NUP43 -3319.0
FOXO1 -3310.0
PTAFR -3295.0
MAP2K7 -3285.0
HLA-H -3279.0
SMARCA4 -3271.0
CASP8 -3233.0
CCR2 -3231.0
TNFSF12 -3187.0
TRIM45 -3182.0
EIF4G2 -3162.0
TXLNA -3136.0
NFKB1 -3133.0
POU2F1 -3130.0
NUP35 -3128.0
CXCL8 -3101.0
SOX2 -3095.0
PIK3CG -3094.0
POMC -3062.0
PIAS1 -3056.0
UBE2E1 -3038.0
PSMD5 -2953.0
RPS6KA1 -2943.0
TRIM2 -2931.0
SH2B1 -2930.0
IRAK4 -2908.0
PSMB7 -2811.0
PSMC5 -2753.0
CFL1 -2704.0
TRIM35 -2696.0
CANX -2679.0
TRAF2 -2645.0
IFI6 -2639.0
TEC -2541.0
SLA2 -2500.0
IL17A -2492.0
BCL6 -2413.0
HSPA8 -2392.0
PSMD3 -2367.0
MAP2K3 -2274.0
NUP214 -2260.0
IFI30 -2247.0
UBE2M -2239.0
IL18RAP -2234.0
EIF4G3 -2095.0
OPRM1 -2020.0
KPNB1 -2017.0
TSLP -1950.0
LAMA5 -1946.0
HIF1A -1895.0
EIF4E3 -1838.0
PSMD6 -1831.0
NUP93 -1824.0
NANOG -1796.0
TNFRSF18 -1760.0
IL17F -1713.0
CDKN1B -1705.0
SOCS3 -1657.0
PTPN14 -1613.0
TNFRSF11B -1580.0
IRF5 -1525.0
UBE2N -1518.0
EIF4A3 -1485.0
IL20 -1433.0
HNRNPA2B1 -1410.0
TRIM46 -1386.0
CNN2 -1371.0
PSMD7 -1362.0
ABL2 -1335.0
EIF4A2 -1297.0
CAPZA1 -1292.0
MAPK1 -1262.0
LIF -1247.0
IL18R1 -1178.0
IFIT5 -1141.0
IL37 -1139.0
FBXW11 -1101.0
ITGAX -1090.0
ATF1 -1084.0
IL1RN -1077.0
IFITM1 -1070.0
IL31 -1037.0
VAV1 -1031.0
VIM -947.0
TNFRSF4 -913.0
FYN -804.0
TRIM3 -793.0
RORA -778.0
PDE12 -746.0
CDC42 -698.0
NFKB2 -677.0
NUP54 -626.0
TOLLIP -612.0
IFNGR2 -599.0
IL1R2 -562.0
CUL5 -510.0
PIK3R3 -472.0
TNFRSF17 -436.0
SNRPA1 -401.0
ELOC -362.0
PSMA1 -272.0
IFNA13 -172.0
GRB10 -135.0
BTRC -91.0
OAS1 -85.0
PSME1 -45.0
TRIM6 -27.0
TBK1 -8.0
SLA -2.0
SP100 30.0
IL23R 78.0
PSMC2 97.0
CLCF1 124.0
OPRD1 139.0
IL6ST 144.0
CD40 146.0
H3C11 151.0
CRLF1 207.0
PSMD1 215.0
EGR1 232.0
IL31RA 268.0
AKT3 336.0
PELI1 343.0
DUSP6 387.0
TNFSF13B 428.0
SOS2 429.0
THOC5 441.0
RNASEL 448.0
BCL2L11 458.0
IL15 461.0
IRF4 563.0
CBL 586.0
TAB1 598.0
CAMK2G 599.0
BCL2 612.0
MX2 614.0
RPS6KA2 661.0
TAB2 685.0
NUP155 699.0
PSMB6 781.0
STAT5A 788.0
ABCE1 821.0
IFIT1 846.0
PPP2R1B 892.0
NFKBIA 1005.0
CCL3 1037.0
HERC5 1047.0
HLA-DRA 1062.0
PIK3CB 1073.0
NCAM1 1102.0
FASLG 1154.0
SUMO1 1175.0
SOD2 1182.0
MAP2K6 1198.0
PTK2B 1214.0
CD44 1237.0
UBA3 1249.0
PTPN13 1353.0
CISH 1406.0
POM121C 1437.0
STX3 1553.0
MAP3K8 1562.0
IL11RA 1572.0
ADAR 1621.0
PRLR 1650.0
PSMA7 1653.0
IL1B 1688.0
BIRC3 1698.0
NEDD4 1707.0
ADAM17 1716.0
PSMA3 1747.0
GSDMD 1786.0
KPNA2 1830.0
IL33 1873.0
PSMA2 1886.0
MEF2C 1924.0
NUP188 1951.0
PDCD4 1967.0
IL22RA2 1979.0
IFNB1 2004.0
RHOU 2009.0
BIRC5 2072.0
MAPK10 2096.0
HLA-DRB5 2136.0
TRAF6 2148.0
TRAF3 2206.0
FSCN1 2262.0
IP6K2 2307.0
IL21R 2434.0
GBP5 2454.0
CSF2RB 2536.0
CD36 2576.0
RELA 2577.0
NOD2 2618.0
MYD88 2621.0
CD86 2662.0
IRF2 2698.0
POM121 2707.0
KPNA3 2725.0
RAG1 2737.0
SEC13 2762.0
IL18BP 2766.0
CDKN1A 2787.0
CREB1 2805.0
MAPK11 2820.0
ALOX5 2821.0
OSMR 2858.0
IRF8 2913.0
PTPN1 2918.0
GHR 2927.0
LIFR 2936.0
PSMB9 2951.0
IL1RAP 2968.0
IL24 2980.0
CD27 3080.0
HLA-DQB1 3100.0
DUSP4 3211.0
TRIM14 3273.0
P4HB 3386.0
FLT3 3400.0
SMAD3 3457.0
CCR5 3473.0
PSMA6 3500.0
GBP1 3544.0
STXBP2 3580.0
AAAS 3650.0
ISG15 3654.0
TNFSF9 3671.0
FLNB 3765.0
PSMC6 3773.0
PTPRJ 3799.0
EIF4A1 3814.0
STX4 3883.0
HLA-G 3890.0
OSM 3931.0
CAMK2D 3959.0
OASL 3979.0
KPNA7 4149.0
TRIM17 4184.0
RANBP2 4244.0
TNFRSF9 4249.0
TRIM25 4288.0
ITGAM 4342.0
LTB 4418.0
NOS2 4447.0
PTPN7 4448.0
PSME3 4494.0
IRS1 4535.0
IL27RA 4541.0
FN1 4581.0
PSMC3 4583.0
LMNB1 4711.0
HLA-C 4768.0
SHC1 4832.0
SAA1 4861.0
PSMB2 4923.0
IL17RC 5082.0
SNAP25 5090.0
IL1RL1 5172.0
CAMK2A 5175.0
IRAK2 5182.0
MAP2K1 5187.0
OAS2 5369.0
NUP85 5382.0
INPP5D 5405.0
IFI27 5409.0
PSMB1 5472.0
IL25 5496.0
TNFRSF6B 5500.0
MAP2K4 5503.0
PRKCD 5516.0
IL36RN 5522.0
HLA-DPB1 5545.0
CUL1 5560.0
PSMC1 5640.0
GAB2 5678.0
PSMD8 5747.0
TRIM8 5763.0
FGF2 5798.0
H3C8 5831.0
IFIT3 5849.0
TRIM38 5866.0
TNFRSF11A 5879.0
TRIM26 5924.0
CCR1 5960.0
SOD1 5985.0
TNF 6076.0
N4BP1 6108.0
MMP2 6110.0
UBE2D1 6123.0
RAE1 6150.0
COL1A2 6208.0
NLRX1 6255.0
SAMHD1 6329.0
S100B 6364.0
IL10RA 6441.0
NKIRAS2 6479.0
IL2 6486.0
PSMB10 6504.0
CXCL1 6548.0
IL1R1 6554.0
HCK 6570.0
LCK 6595.0
UBE2V1 6602.0
TRIM62 6606.0
HSP90AA1 6611.0
FOXO3 6649.0
CCL5 6673.0
IL1RL2 6685.0
TNFSF4 6690.0
HSPA9 6756.0
IFNAR1 6772.0
STAT6 6778.0
TP53 6860.0
CA1 6905.0
TCP1 6937.0
APP 6979.0
SRC 7032.0
ISG20 7096.0
PSMA4 7118.0
VRK3 7130.0
PSMD4 7146.0
NUP133 7196.0
EDAR 7206.0
TNFRSF1A 7280.0
H3C4 7300.0
IL18 7335.0
GBP3 7343.0
CCL20 7369.0
TRIM5 7492.0
IL17C 7521.0
PSMC4 7533.0
SOS1 7541.0
TNFSF18 7635.0
H3C6 7676.0
VCAM1 7681.0
HLA-DQA2 7691.0
GBP7 7702.0
CTF1 7744.0
NDN 7775.0
TRIM68 7837.0
IL16 7865.0
IL5 7870.0
PRL 7990.0
SKP1 8064.0
ALPK1 8105.0
RNF7 8213.0
MMP3 8214.0
TNFSF8 8219.0
H3C2 8265.0
IL7 8285.0
PSMA5 8306.0
TNFSF11 8401.0
RIGI 8418.0
IL26 8475.0
IL20RB 8502.0
CD80 8508.0
SH2B3 8517.0
IL11 8528.0
PSMF1 8543.0
TNFRSF13C 8557.0
GBP2 8573.0
MAPK7 8612.0
UBA52 8631.0
TRIM10 8710.0
HLA-DPA1 8764.0
MUC1 8790.0
NUP88 8810.0
TNFRSF13B 8817.0
IL1A 8830.0
PTPN11 8872.0
STAT2 9014.0
EIF4G1 9082.0
PPP2R1A 9244.0
IL36B 9290.0
PPP2CB 9331.0
HLA-DQB2 9382.0
CSF3 9384.0
PTPN5 9387.0
IFNA16 9425.0
IL1F10 9447.0
PSMD12 9475.0
CSF3R 9499.0
FCER2 9527.0
IFNA7 9573.0
TNFSF15 9584.0
CIITA 9600.0
CSF1R 9655.0
CTSG 9706.0
IL23A 9719.0
IFNA14 9747.0
LBP 9796.0
IL34 9811.0
BLNK 9917.0
IL36A 9963.0
IL3 10126.0
LCN2 10186.0
FPR1 10222.0
IFNA8 10300.0
CCL22 10303.0
S100A12 10306.0
IFITM3 10330.0
CCL19 10453.0
CCL2 10462.0
CCL11 10464.0
GH1 10529.0
CSF2 10602.0
GH2 10867.0


REACTOME_VISUAL_PHOTOTRANSDUCTION

REACTOME_VISUAL_PHOTOTRANSDUCTION
473
set REACTOME_VISUAL_PHOTOTRANSDUCTION
setSize 93
pANOVA 9.67e-05
s.dist 0.234
p.adjustANOVA 0.0176



Top enriched genes

Top 20 genes
GeneID Gene Rank
CLPS 10931
AKR1B10 10922
GNGT1 10866
RBP3 10677
APOA4 10551
AKR1C4 10301
RHO 10289
TTR 10144
APOC3 10060
APOM 9983
GPIHBP1 9919
RPE65 9789
SDR9C7 9394
RLBP1 9332
GUCA1A 9242
SAG 9206
RBP2 9200
PLB1 9070
HSD17B1 8968
APOA1 8719

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CLPS 10931
AKR1B10 10922
GNGT1 10866
RBP3 10677
APOA4 10551
AKR1C4 10301
RHO 10289
TTR 10144
APOC3 10060
APOM 9983
GPIHBP1 9919
RPE65 9789
SDR9C7 9394
RLBP1 9332
GUCA1A 9242
SAG 9206
RBP2 9200
PLB1 9070
HSD17B1 8968
APOA1 8719
LRP2 8644
LRP10 8564
BCO2 8225
RDH12 8111
SDC4 7989
GRK7 7803
BCO1 7593
GUCY2D 7332
STRA6 7160
RDH8 6990
AKR1C1 6671
ABCA4 6270
PRKCA 6082
RDH11 5643
GNAT1 5532
DHRS9 5286
AKR1C3 5194
RDH10 5089
RDH16 4868
FNTB 4732
PDE6A 4619
MYO7A 4512
HSPG2 4343
APOE 4315
CYP4V2 4118
GRK4 4107
LRP1 4007
PDE6B 3559
RCVRN 3428
CNGB1 3235
GNB1 3133
LDLR 3034
APOC2 2945
GPC6 1893
SDC2 1590
FNTA 1434
SLC24A1 1096
APOB 1065
CNGA1 890
LPL 864
NMT2 675
RETSAT 536
HSD17B6 128
PDE6G -921
GNB5 -937
CALM1 -1041
METAP2 -1749
GRK1 -1954
GUCA1C -2238
GPC2 -2311
RGS9BP -2646
GPC5 -2838
CAMKMT -2963
LRP12 -3402
RDH5 -4076
PNLIP -4443
SDC1 -4818
GPC1 -5187
DHRS3 -5684
LRP8 -5686
AGRN -5809
NMT1 -5998
LRAT -6073
RBP4 -6512
PRKCQ -6644
SDC3 -8144
OPN1SW -8419
METAP1 -8454
RBP1 -8536
NAPEPLD -9312
GUCA1B -9469
RGS9 -9787
APOA2 -10860


REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS

REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS
601
set REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS
setSize 188
pANOVA 0.000153
s.dist 0.16
p.adjustANOVA 0.0252



Top enriched genes

Top 20 genes
GeneID Gene Rank
CCL21 10823
CCL27 10790
CXCL11 10704
XCL2 10629
PROK1 10571
RXFP4 10542
PROKR1 10508
ACKR1 10497
CCL11 10464
CCL2 10462
CCL19 10453
CXCL9 10402
CXCR1 10400
ACKR4 10380
CCL22 10303
MCHR1 10299
CCL7 10251
FPR1 10222
PRLH 10198
FPR2 9833

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CCL21 10823
CCL27 10790
CXCL11 10704
XCL2 10629
PROK1 10571
RXFP4 10542
PROKR1 10508
ACKR1 10497
CCL11 10464
CCL2 10462
CCL19 10453
CXCL9 10402
CXCR1 10400
ACKR4 10380
CCL22 10303
MCHR1 10299
CCL7 10251
FPR1 10222
PRLH 10198
FPR2 9833
NTS 9756
CXCL5 9649
QRFP 9626
AVP 9523
SSTR3 9513
MLNR 9417
GPR37L1 9401
CCR3 9339
KNG1 9260
TAC3 9245
CCL16 9166
NPB 9095
CCR10 8995
GALR3 8868
CXCR5 8864
EDN1 8786
ACKR3 8779
PF4 8616
CXCL13 8459
AGT 8394
C3AR1 8200
CCRL2 8084
CCR4 8006
TACR2 7958
EDNRA 7806
CCKAR 7773
GALR1 7653
C5AR2 7612
RXFP2 7518
BDKRB1 7464
PPY 7450
CXCR2 7444
CX3CL1 7433
XCL1 7425
CCL20 7369
CX3CR1 7009
APP 6979
RXFP1 6836
CCL5 6673
KEL 6654
CXCL1 6548
NTSR2 6465
MC3R 6318
HCRT 6148
ACKR2 6048
CCR1 5960
FPR3 5938
C5 5885
XCR1 5759
CXCL16 5754
KISS1 5731
C5AR1 5619
MC2R 5615
PRLHR 5562
AGTR1 5444
EDN2 5387
NPSR1 5291
PROK2 5264
F2 5015
BDKRB2 4929
PSAP 4915
SAA1 4861
CCL1 4827
GAL 4640
CORT 4542
PMCH 4483
NPY 4165
AVPR1B 4019
INSL5 3986
GALR2 3941
CCR8 3902
NPFFR1 3846
EDN3 3792
CCR5 3473
CCL17 3403
HCRTR1 3380
GPR37 3308
NTSR1 3155
CXCL6 3141
CCL25 2892
PPBP 2850
TACR1 2822
NMS 2506
NLN 2374
KISS1R 2029
NPFFR2 1756
TRHR 1729
CCL3 1037
CCR7 1001
QRFPR 904
PROKR2 893
CXCR6 818
NPS 736
NPBWR2 644
MC5R 158
OPRD1 139
GPER1 -1
PENK -431
PYY -684
F2RL3 -857
C3 -1115
PNOC -1687
OPRM1 -2020
PDYN -2179
NPY2R -2224
ECE2 -2305
HEBP1 -2389
GRP -2947
POMC -3062
CXCL8 -3101
MC1R -3198
CCR2 -3231
ECE1 -3496
MLN -3800
CXCL2 -3874
TACR3 -3919
NPBWR1 -4112
SST -4116
SSTR5 -4213
CXCL12 -4284
CXCR4 -4374
OXT -4455
CCL28 -4503
AVPR1A -4743
CCKBR -4855
UTS2B -4895
NPFF -4979
CCL13 -5265
GHSR -5266
MCHR2 -5387
OPRL1 -5510
SSTR2 -5603
F2R -5657
UTS2R -5676
OXTR -5849
APLNR -6124
NMB -6377
UTS2 -6689
SSTR4 -6776
INSL3 -7175
RXFP3 -7397
EDNRB -7684
GHRL -8027
F2RL1 -8084
CXCL10 -8093
F2RL2 -8350
ANXA1 -8847
SSTR1 -8925
NPY1R -8972
NPY5R -9125
CCR6 -9136
OPRK1 -9324
TRH -9444
CCK -9598
TAC1 -9677
NMUR1 -9759
CCL23 -9803
NMUR2 -9996
NPW -10020
NMU -10034
HCRTR2 -10051
CXCL3 -10102
MC4R -10228
NMBR -10257
RLN3 -10491
CCR9 -10511
RLN2 -10740
CCL4 -11032


REACTOME_HIV_LIFE_CYCLE

REACTOME_HIV_LIFE_CYCLE
168
set REACTOME_HIV_LIFE_CYCLE
setSize 145
pANOVA 0.000182
s.dist -0.18
p.adjustANOVA 0.0272



Top enriched genes

Top 20 genes
GeneID Gene Rank
CDK9 -10699
TPR -10116
UBB -9922
CHMP5 -9794
ELOB -9480
MVB12A -9298
NUP50 -9137
FEN1 -9104
NCBP1 -8960
TAF9 -8893
RAN -8481
ELOA -8452
SUPT4H1 -8219
NUP42 -8147
XPO1 -8068
TAF6 -8059
POLR2E -7862
NELFCD -7846
LIG1 -7782
HMGA1 -7648

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CDK9 -10699
TPR -10116
UBB -9922
CHMP5 -9794
ELOB -9480
MVB12A -9298
NUP50 -9137
FEN1 -9104
NCBP1 -8960
TAF9 -8893
RAN -8481
ELOA -8452
SUPT4H1 -8219
NUP42 -8147
XPO1 -8068
TAF6 -8059
POLR2E -7862
NELFCD -7846
LIG1 -7782
HMGA1 -7648
NUP98 -7640
FURIN -7547
NUP62 -7441
CCNT2 -7423
GTF2H5 -7198
POLR2D -7167
SEH1L -7114
TAF4 -7074
CHMP4C -6983
NUP160 -6888
TAF2 -6818
GTF2H1 -6694
CHMP2B -6673
NDC1 -6638
TSG101 -6609
SUPT16H -6608
NUP205 -6549
NUP58 -6523
VPS37D -6347
POLR2H -6221
NUP37 -6122
NMT1 -5998
RPS27A -5865
KPNA1 -5788
RANBP1 -5762
CHMP3 -5755
GTF2E1 -5695
LIG4 -5349
CD4 -5234
PSIP1 -5188
NUP210 -5101
NUP153 -5090
RANGAP1 -5063
UBAP1 -4994
PPIA -4974
NUP107 -4906
PDCD6IP -4704
CHMP7 -4660
VPS28 -4654
POLR2B -4576
TAF3 -4447
BANF1 -4441
RNMT -4436
CXCR4 -4374
CHMP4A -4321
ELL -4066
UBC -3937
RCC1 -3906
XRCC6 -3851
NUP43 -3319
NUP35 -3128
VPS4A -2952
CTDP1 -2893
GTF2A2 -2825
CCNT1 -2694
POLR2J -2572
NUP214 -2260
NELFE -2161
TAF12 -2056
GTF2F1 -1941
CDK7 -1843
NUP93 -1824
RNGTT -1795
POLR2C -1770
NELFB -1717
CHMP4B -1574
TAF5 -1384
ERCC2 -1327
CHMP6 -1065
VPS37A -1028
TBP -894
TAF15 -667
NUP54 -626
ELOC -362
VPS4B 286
VTA1 443
NMT2 675
NUP155 699
POLR2A 926
POLR2F 952
TAF11 1035
MVB12B 1078
NCBP2 1108
SUPT5H 1279
POM121C 1437
POLR2L 1607
SSRP1 1699
CCNK 1834
NUP188 1951
XRCC4 2316
POM121 2707
SEC13 2762
GTF2H3 3037
VPS37C 3048
GTF2B 3312
CCR5 3473
NELFA 3536
AAAS 3650
POLR2K 3831
MNAT1 3936
GTF2H4 4003
RANBP2 4244
GTF2A1 4397
POLR2G 4485
TAF4B 4648
VPS37B 4932
TAF1L 4990
ERCC3 5084
NUP85 5382
XRCC5 5400
GTF2F2 5497
CCNH 5718
CHMP2A 5744
TAF13 5751
RAE1 6150
GTF2E2 6307
TAF7 7083
NUP133 7196
POLR2I 7727
NEDD4L 8335
UBA52 8631
NUP88 8810
TAF10 9057
ELOA2 9558
TCEA1 10191


REACTOME_INFECTIOUS_DISEASE

REACTOME_INFECTIOUS_DISEASE
974
set REACTOME_INFECTIOUS_DISEASE
setSize 910
pANOVA 0.000319
s.dist -0.0704
p.adjustANOVA 0.041



Top enriched genes

Top 20 genes
GeneID Gene Rank
TUBA3D -10927
H2AC14 -10913
H3C12 -10835
BRK1 -10788
BST2 -10781
PSMB11 -10777
H2BC14 -10763
RPL39L -10742
CDK9 -10699
HLA-F -10607
MOGS -10503
ATG14 -10343
KEAP1 -10320
IFNA5 -10314
H4C9 -10310
H2AC20 -10156
TPR -10116
IFNA1 -10080
P2RX4 -10076
GNG3 -10058

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TUBA3D -10927.0
H2AC14 -10913.0
H3C12 -10835.0
BRK1 -10788.0
BST2 -10781.0
PSMB11 -10777.0
H2BC14 -10763.0
RPL39L -10742.0
CDK9 -10699.0
HLA-F -10607.0
MOGS -10503.0
ATG14 -10343.0
KEAP1 -10320.0
IFNA5 -10314.0
H4C9 -10310.0
H2AC20 -10156.0
TPR -10116.0
IFNA1 -10080.0
P2RX4 -10076.0
GNG3 -10058.0
PPIB -10015.0
GNG8 -9993.0
IFNA21 -9991.0
UBB -9922.0
PLCG1 -9896.0
MGAT4A -9895.0
RPL36 -9806.0
TUBB4A -9800.0
CHMP5 -9794.0
RPLP2 -9722.0
TGFB1 -9661.0
CEBPD -9648.0
CRBN -9568.0
H2BC3 -9544.0
RPL18 -9526.0
IRF7 -9515.0
EZH2 -9507.0
CD28 -9503.0
ELOB -9480.0
SEM1 -9467.0
GRSF1 -9422.0
H2BC9 -9300.5
H3C7 -9300.5
MVB12A -9298.0
MAP3K7 -9289.0
HLA-B -9281.0
RCAN3 -9221.0
APOBEC3G -9198.0
TUBB1 -9184.0
FKBP4 -9167.0
ELMO2 -9162.0
NUP50 -9137.0
FZD7 -9111.0
FEN1 -9104.0
CYBA -9072.0
DPEP1 -9001.0
NCBP1 -8960.0
NFE2L2 -8950.0
PARP9 -8929.0
TAF9 -8893.0
PSMD14 -8863.0
SAP30L -8829.0
GNG10 -8827.0
MYO1C -8796.0
SYK -8792.0
RPS9 -8791.0
ACTB -8733.0
ZDHHC20 -8711.0
ISCU -8709.0
CD247 -8686.0
CORO1A -8668.0
ARPC1A -8665.0
ANO3 -8643.0
H3C1 -8620.0
RPS5 -8592.0
PARP14 -8581.0
TRIM28 -8551.0
H3C3 -8519.0
RPL13 -8484.0
RAN -8481.0
H2AC15 -8462.0
VCP -8460.0
ELOA -8452.0
ARF1 -8415.0
H4C16 -8404.0
CYSLTR2 -8391.0
MBD3 -8372.0
H2BC21 -8354.0
JAK2 -8304.0
NCKAP1 -8253.0
SUPT4H1 -8219.0
CD9 -8194.0
NUP42 -8147.0
SDC3 -8144.0
MYH9 -8128.0
VEGFA -8125.0
PRKACA -8098.0
PABPN1 -8097.0
XPO1 -8068.0
TAF6 -8059.0
IFNA2 -8022.0
CASP1 -7993.0
HDAC1 -7942.0
PDPK1 -7939.0
DNAJC3 -7905.0
RPL3L -7894.0
PAK2 -7893.0
B2M -7892.0
JAK1 -7873.0
POLR2E -7862.0
HLA-E -7859.0
NELFCD -7846.0
YWHAZ -7837.0
NCKIPSD -7835.0
H4C12 -7830.0
ITGB1 -7812.0
VPS16 -7802.0
LIG1 -7782.0
IRF3 -7750.0
VAMP2 -7723.0
TUBAL3 -7714.0
ANO5 -7683.0
HMGA1 -7648.0
NUP98 -7640.0
CTSL -7633.0
IL10 -7610.0
RPSA -7578.0
NOD1 -7572.0
FURIN -7547.0
MAPK3 -7536.0
NLRP12 -7480.0
SUDS3 -7460.0
NUP62 -7441.0
TUSC3 -7440.0
MGAT4B -7426.0
YES1 -7425.0
CCNT2 -7423.0
FCGR3A -7415.0
ZCRB1 -7398.0
MAPK8 -7394.0
SNF8 -7369.0
H2AC16 -7367.0
VPS39 -7366.0
FXYD1 -7334.0
STT3A -7307.0
FCGR2A -7234.0
GTF2H5 -7198.0
POLR2D -7167.0
DPEP3 -7141.0
SEH1L -7114.0
TAF4 -7074.0
TUBB2B -7059.0
TUBB -7034.0
GPS2 -7024.0
CHMP4C -6983.0
MTA2 -6980.0
PSMD9 -6945.0
GOLGA7 -6943.0
CSNK1A1 -6942.0
PARP6 -6912.0
UBE2I -6911.0
NUP160 -6888.0
TAF2 -6818.0
PRKAR1A -6801.0
TMPRSS2 -6753.0
ZDHHC2 -6749.0
GTF2H1 -6694.0
CHMP2B -6673.0
NT5E -6665.0
MTA3 -6658.0
NDC1 -6638.0
IFNA6 -6637.0
TSG101 -6609.0
SUPT16H -6608.0
KDM1A -6600.0
ENTPD5 -6586.0
NUP205 -6549.0
PLK2 -6539.0
TRIM4 -6535.0
NUP58 -6523.0
IFNGR1 -6516.0
PSMB8 -6491.0
KPNA5 -6485.0
PTGES3 -6480.0
RAC1 -6469.0
RPL18A -6458.0
TBL1XR1 -6448.0
ZDHHC8 -6420.0
SEC24C -6368.0
EP300 -6367.0
VPS37D -6347.0
PARP4 -6326.0
IFNAR2 -6312.0
RPS10 -6311.0
S1PR1 -6304.0
TUBB2A -6285.0
POLR2H -6221.0
RPLP0 -6181.0
STAM2 -6140.0
NUP37 -6122.0
PLCG2 -6119.0
H2BC15 -6116.0
RPS27L -6070.0
CRK -6052.0
PSMA8 -6030.0
NMT1 -5998.0
RNF135 -5931.0
RPS27A -5865.0
PSMD13 -5830.0
AGRN -5809.0
HNRNPA1 -5803.0
KPNA1 -5788.0
ROCK2 -5783.0
RANBP1 -5762.0
CHMP3 -5755.0
PTPN6 -5744.0
ATP1A1 -5743.0
PSME4 -5742.0
HSP90AB1 -5719.0
GTF2E1 -5695.0
RPL26L1 -5690.0
RBX1 -5685.0
RPL37A -5670.0
BCL2L1 -5668.0
RPL7A -5630.0
EIF2AK2 -5557.0
TXNIP -5549.0
H2BC26 -5544.0
TYK2 -5493.0
RUNX1 -5488.0
RPL7 -5470.0
AKT1 -5462.0
ADCY7 -5455.0
STAT1 -5422.0
IL6 -5414.0
ARPC1B -5406.0
PSMD11 -5394.0
LIG4 -5349.0
TUBA1B -5322.0
FXYD2 -5320.0
WASL -5319.0
BECN1 -5275.0
CD4 -5234.0
PSMB3 -5218.0
GRB2 -5215.0
PSIP1 -5188.0
GPC1 -5187.0
JAK3 -5160.0
ROCK1 -5125.0
NUP210 -5101.0
NUP153 -5090.0
RANGAP1 -5063.0
ITGA4 -5018.0
MAPK14 -4997.0
UBAP1 -4994.0
GNG13 -4992.0
RIPK2 -4991.0
PPIA -4974.0
H2AC25 -4934.0
AP2A1 -4922.0
ATP1A4 -4912.0
NUP107 -4906.0
RPN2 -4904.0
KPNA4 -4881.0
RPL11 -4856.0
ITPR2 -4832.0
NCKAP1L -4829.0
SDC1 -4818.0
CBX1 -4768.0
ITPR1 -4737.0
PDCD6IP -4704.0
SV2A -4690.0
GNGT2 -4682.0
MGAT4C -4669.0
CHMP7 -4660.0
IKBKB -4657.0
ACTR3 -4655.0
VPS28 -4654.0
SEC23A -4621.0
ACTG1 -4615.0
DYNC1I1 -4614.0
HLA-A -4587.0
POLR2B -4576.0
NR3C1 -4518.0
H2AC18 -4497.5
H2AC19 -4497.5
GNAI1 -4496.0
H3C10 -4463.0
ARPC3 -4451.0
TAF3 -4447.0
TJP1 -4442.0
BANF1 -4441.0
ARPC4 -4440.0
RNMT -4436.0
ARID4B -4431.0
DYNC1LI1 -4424.0
LYN -4414.0
RPL5 -4410.0
MEFV -4407.0
ABI2 -4376.0
CXCR4 -4374.0
STX1A -4369.0
AP2B1 -4349.0
ST3GAL1 -4346.0
CHMP4A -4321.0
YWHAB -4317.0
PML -4271.0
PSMB5 -4259.0
ADCY4 -4232.0
RPS29 -4224.0
RPL22L1 -4163.0
CHUK -4148.0
PRKCSH -4145.0
H2BC12 -4085.0
ELL -4066.0
PSME2 -4065.0
ADORA2B -4062.0
BRD4 -4039.0
RPS16 -4022.0
RPL19 -4018.0
AKT2 -4008.0
SP1 -4003.0
HMOX1 -3970.0
PSMD2 -3966.0
UBC -3937.0
STAM -3922.0
RCC1 -3906.0
ANO8 -3904.0
EEF2 -3889.0
GNG2 -3853.0
XRCC6 -3851.0
MYH2 -3782.0
SLC25A4 -3772.0
TUBA8 -3728.0
TUBB4B -3663.0
IL17RA -3660.0
IL6R -3631.0
RPS14 -3626.0
PATJ -3616.0
HGS -3601.0
RPL31 -3566.0
RHBDF2 -3533.0
VPS45 -3529.0
MAP1LC3B -3527.0
PSMB4 -3508.0
MGAT1 -3468.0
PACS1 -3465.0
JUN -3450.0
DYNLL1 -3346.0
ARPC2 -3330.0
SFTPD -3324.0
NUP43 -3319.0
UVRAG -3316.0
H4C11 -3297.0
MAP2K7 -3285.0
IFIH1 -3173.0
SERPINE1 -3164.0
NFKB1 -3133.0
NUP35 -3128.0
COMT -3122.0
RPS6 -3092.0
RPS11 -3081.0
MYO5A -3072.0
RIPK1 -3070.0
RPL15 -3043.0
EEF1A1 -2974.0
PSMD5 -2953.0
VPS4A -2952.0
H2AC6 -2934.0
PCBP2 -2926.0
SH3GL2 -2924.0
CTDP1 -2893.0
ATP1A3 -2879.0
PIK3C3 -2844.0
GPC5 -2838.0
GTF2A2 -2825.0
CLTC -2818.0
PSMB7 -2811.0
ADCY9 -2810.0
PARP16 -2808.0
CRB3 -2766.0
PSMC5 -2753.0
H4C1 -2748.0
AP1S1 -2727.0
CCNT1 -2694.0
CANX -2679.0
ZDHHC5 -2660.0
POLR2J -2572.0
ADCY3 -2547.0
DYNC1I2 -2526.0
IL17A -2492.0
TLR2 -2381.0
PSMD3 -2367.0
GPC2 -2311.0
RPL24 -2291.0
MAP2K3 -2274.0
NUP214 -2260.0
MAN1B1 -2190.0
SRPK2 -2170.0
NELFE -2161.0
CHMP1A -2099.0
SYT2 -2092.0
RAB5A -2060.0
TAF12 -2056.0
ST6GAL1 -2053.0
EGFR -2039.0
RPL3 -2024.0
KPNB1 -2017.0
H4C13 -1989.0
NPM1 -1969.0
AP1M2 -1967.0
H4C6 -1963.0
GTF2F1 -1941.0
P2RX7 -1903.0
GGT1 -1876.0
CD3G -1871.0
NCK1 -1846.0
CDK7 -1843.0
CD163 -1833.0
PSMD6 -1831.0
NUP93 -1824.0
RNGTT -1795.0
POLR2C -1770.0
RPS21 -1738.0
NELFB -1717.0
IL17F -1713.0
EDEM2 -1690.0
YWHAQ -1651.0
DAD1 -1605.0
CHMP4B -1574.0
H4C3 -1564.0
UBE2N -1518.0
AP1G1 -1501.0
RPL30 -1411.0
GNAT3 -1408.0
CNBP -1389.0
TAF5 -1384.0
PSMD7 -1362.0
MTA1 -1333.0
ANO7 -1331.0
ERCC2 -1327.0
H2AC1 -1303.0
WIPF1 -1296.0
MAPK1 -1262.0
RPL17 -1242.0
RNF213 -1235.0
HNRNPK -1207.0
PIK3R4 -1175.0
NOXA1 -1122.0
C3 -1115.0
SH3GL1 -1075.0
CHMP6 -1065.0
CALM1 -1041.0
VAV1 -1031.0
VPS37A -1028.0
RIPK3 -1004.0
RPL10L -952.0
GNB5 -937.0
RPL38 -915.0
RPL21 -896.0
TBP -894.0
RPS28 -888.0
ABI1 -864.0
VAMP1 -856.0
IMPDH1 -842.0
FYN -804.0
RPS8 -801.0
CDC42 -698.0
NFKB2 -677.0
TAF15 -667.0
HDAC3 -661.0
NUP54 -626.0
GEMIN7 -620.0
GSK3B -613.0
CREBBP -600.0
IFNGR2 -599.0
VAV3 -548.0
DVL3 -547.0
CUL5 -510.0
DYNLL2 -501.0
FUT8 -487.0
CHD4 -474.0
TUBA1C -435.0
ST3GAL4 -430.0
TUBB3 -380.0
GNAZ -379.0
SIGMAR1 -365.0
RPS7 -364.0
ELOC -362.0
SFPQ -345.0
NMI -338.0
RPS3A -293.0
PSMA1 -272.0
ST3GAL2 -233.0
TUBA3C -228.0
RPL29 -197.0
ATP1A2 -181.0
IFNA13 -172.0
SV2C -169.0
BTRC -91.0
RPL23A -76.0
PSME1 -45.0
TBK1 -8.0
TUBA1A 53.0
ANO1 71.0
PSMC2 97.0
CTNNB1 114.0
H3C11 151.0
TKFC 212.0
PSMD1 215.0
GATAD2A 243.0
RCOR1 253.0
VPS4B 286.0
ELMO1 331.0
AKT3 336.0
PRMT1 395.0
VTA1 443.0
ANTXR2 535.0
SNRPD3 554.0
SAR1B 571.0
CBL 586.0
TAB1 598.0
NMT2 675.0
G3BP1 681.0
TAB2 685.0
NUP155 699.0
PSMB6 781.0
TUFM 806.0
GNAI3 842.0
GJA1 869.0
POLR2A 926.0
POLR2F 952.0
DDX20 956.0
MYO9B 960.0
FXYD4 983.0
DYNC1H1 1000.0
GALNT1 1002.0
NFKBIA 1005.0
YWHAE 1028.0
TAF11 1035.0
VPS18 1036.0
CDH1 1070.0
MVB12B 1078.0
SRPK1 1082.0
EPS15 1097.0
NCBP2 1108.0
GSK3A 1163.0
RPL35A 1168.0
SUMO1 1175.0
MAP2K6 1198.0
RPL10A 1215.0
GNG12 1262.0
SUPT5H 1279.0
EED 1280.0
RPS18 1294.0
HAVCR1 1419.0
SYT1 1429.0
FNTA 1434.0
POM121C 1437.0
ST6GALNAC4 1458.0
IPO5 1473.0
DOCK2 1482.0
DAXX 1511.0
RPL6 1517.0
ATP1B1 1526.0
RPL8 1548.0
SDC2 1590.0
POLR2L 1607.0
AP1M1 1624.0
PSMA7 1653.0
IL1B 1688.0
SSRP1 1699.0
ADAM17 1716.0
PSMA3 1747.0
ANO4 1772.0
GSDMD 1786.0
AP1S3 1798.0
PRKAR2B 1811.0
ANO10 1821.0
VPS36 1822.0
KPNA2 1830.0
CCNK 1834.0
CLTA 1840.0
ACTR2 1872.0
PSMA2 1886.0
GPC6 1893.0
NUP188 1951.0
ABL1 1983.0
HBEGF 1986.0
GNG7 1989.0
IFNB1 2004.0
GEMIN4 2011.0
ATP1B2 2018.0
RAB7A 2025.0
CPSF4 2038.0
PARP1 2043.0
SUGT1 2066.0
CBLL1 2068.0
PSTPIP1 2092.0
PHF21A 2116.0
H4C5 2140.0
TRAF6 2148.0
RPS15 2186.0
TRAF3 2206.0
ANO6 2222.0
GEMIN5 2242.0
MYO10 2277.0
XRCC4 2316.0
GGT5 2320.0
TOMM70 2355.0
RPN1 2407.0
ST6GALNAC3 2452.0
ADCY1 2453.0
RPL27 2466.0
H2AC8 2496.0
ADCY8 2498.0
SH3GL3 2522.0
RELA 2577.0
RPS25 2614.0
AP1B1 2617.0
NOD2 2618.0
H2AC7 2644.5
H2BC7 2644.5
GANAB 2663.0
ZDHHC3 2679.0
POM121 2707.0
YWHAG 2714.0
KPNA3 2725.0
SEC13 2762.0
AP2S1 2792.0
VPS33A 2802.0
CREB1 2805.0
SV2B 2806.0
ATP6V1H 2807.0
PPIH 2811.0
BAIAP2 2899.0
DVL2 2900.0
ST3GAL3 2922.0
PSMB9 2951.0
GNG5 2970.0
IMPDH2 2986.0
H2AC21 3029.0
GTF2H3 3037.0
H4C2 3043.0
VPS37C 3048.0
ITPR3 3051.0
H2BC4 3069.0
GNB1 3133.0
SAP18 3162.0
BRMS1 3173.0
PDCD1 3187.0
AP2A2 3233.0
PRKAR1B 3253.0
DVL1 3300.0
GTF2B 3312.0
NCOR2 3341.0
DYNC1LI2 3368.0
MGAT2 3373.5
RPL36AL 3373.5
SNRPD2 3389.0
PRKACB 3408.0
DDOST 3433.0
H2BC1 3439.0
WIPF2 3440.0
STX1B 3447.0
SMAD3 3457.0
TXN 3461.0
CCR5 3473.0
PSMA6 3500.0
RPL4 3509.0
MAN2A1 3517.0
NELFA 3536.0
NCOR1 3553.0
H2BC10 3582.0
SNRPD1 3587.0
CYFIP1 3590.0
FXYD7 3618.0
SMAD4 3622.0
RPS20 3636.0
AAAS 3650.0
ISG15 3654.0
VPS41 3677.0
HDAC2 3695.0
TUBA4B 3701.0
ANTXR1 3754.0
YWHAH 3766.0
PSMC6 3773.0
POLR2K 3831.0
WNT5A 3886.0
HLA-G 3890.0
MNAT1 3936.0
WASF2 3975.0
GTF2H4 4003.0
HMG20B 4040.0
HSPA1A 4050.0
MET 4061.0
CAV1 4085.0
KPNA7 4149.0
RPL41 4173.0
H2AC13 4182.0
RPL37 4234.0
RANBP2 4244.0
G3BP2 4270.0
CYFIP2 4285.0
TRIM25 4288.0
HSPG2 4343.0
PPIG 4373.0
GTF2A1 4397.0
NOS2 4447.0
POLR2G 4485.0
PSME3 4494.0
H4C4 4495.0
TUBA3E 4513.0
DDX5 4556.0
RPS24 4577.0
PSMC3 4583.0
RPS2 4618.0
AP2M1 4621.0
GEMIN6 4635.0
TAF4B 4648.0
H2BC5 4649.0
ARID4A 4656.0
FAU 4665.0
ADCY5 4696.0
FNTB 4732.0
H2BC11 4747.0
HLA-C 4768.0
H2BC13 4779.0
RPL35 4825.0
RPLP1 4851.0
GNAI2 4858.0
PRKAR2A 4866.0
CUL3 4884.0
SEC24A 4899.0
GATAD2B 4901.0
PSMB2 4923.0
VPS37B 4932.0
TAF1L 4990.0
RPS26 5011.0
ARPC5 5064.0
IL17RC 5082.0
ERCC3 5084.0
SNAP25 5090.0
WASF3 5147.0
IRAK2 5182.0
MAP2K1 5187.0
RPS15A 5197.0
ADCY2 5244.0
RPL22 5281.0
H4C8 5287.0
ANO9 5322.0
TXNRD1 5325.0
RPS27 5348.0
TUBA4A 5381.0
NUP85 5382.0
XRCC5 5400.0
GNAS 5452.0
PRKACG 5456.0
PSMB1 5472.0
GTF2F2 5497.0
MAP2K4 5503.0
TRIM27 5508.0
VPS11 5510.0
PALS1 5622.0
PSMC1 5640.0
GNG11 5658.0
CCNH 5718.0
SIKE1 5726.0
CHMP2A 5744.0
PSMD8 5747.0
TAF13 5751.0
NRP1 5758.0
ENO1 5786.0
H3C8 5831.0
FKBP1A 5986.0
ANO2 5990.0
RPL9 6018.0
VHL 6057.0
CALR 6080.0
CD79A 6085.0
RBBP4 6098.0
RAE1 6150.0
CTNND1 6203.0
FGR 6247.0
REST 6265.0
GTF2E2 6307.0
RPS12 6334.0
ADCY6 6370.0
SFN 6381.0
VPS25 6462.0
TLR9 6476.0
PSMB10 6504.0
MAP2K2 6535.0
IL1R1 6554.0
HCK 6570.0
GUCY2C 6581.0
LCK 6595.0
UBE2V1 6602.0
HSP90AA1 6611.0
TUBB6 6645.0
SAP30 6651.0
DOCK1 6661.0
IFNAR1 6772.0
CD79B 6810.0
SUZ12 6827.0
RPL27A 6840.0
GNB4 6854.0
RPL12 6871.0
ENTPD1 6934.0
AHCYL1 6946.0
MAVS 6952.0
MASP1 6976.0
APP 6979.0
RPS3 7019.0
SRC 7032.0
H2BC8 7037.0
TAF7 7083.0
RPS19 7090.0
GNG4 7100.0
PSMA4 7118.0
PSMD4 7146.0
H2BC6 7179.0
NUP133 7196.0
RPL26 7213.0
GNB3 7220.0
SEC24D 7233.0
NOXO1 7234.0
SNRPB 7248.0
SNRPG 7254.0
SNRPF 7267.0
PYCARD 7271.0
LARP1 7274.0
RPL13A 7281.5
H3C4 7300.0
IL18 7335.0
DUSP16 7384.0
MASP2 7399.0
SEC24B 7429.0
ST6GALNAC2 7524.0
SNRPE 7532.0
PSMC4 7533.0
SOS1 7541.0
RPL28 7558.0
ITCH 7559.0
DPEP2 7669.0
H3C6 7676.0
POLR2I 7727.0
RPL14 7772.0
RB1 7828.0
GNB2 7897.0
ZDHHC11 7915.0
SDC4 7989.0
RPS13 7996.0
CD8B 8024.0
SKP1 8064.0
LTF 8129.0
NLRP3 8147.0
H2AC11 8172.0
C3AR1 8200.0
H3C2 8265.0
PSMA5 8306.0
NEDD4L 8335.0
RIGI 8418.0
WASF1 8455.0
SMN1 8499.5
SMN2 8499.5
IKBKE 8536.0
PSMF1 8543.0
RPS23 8609.0
UBA52 8631.0
PKLR 8679.0
VPS33B 8759.0
MGAT5 8767.0
NUP88 8810.0
IL1A 8830.0
PTPN11 8872.0
PTK2 8922.0
RPL34 8944.0
ZBP1 9001.0
STAT2 9014.0
TAF10 9057.0
ATP1B3 9075.0
RPL32 9169.0
FXYD3 9183.0
H2AC4 9304.0
PARP8 9317.0
PARP10 9322.0
VAV2 9364.0
CHD3 9403.0
IFNA16 9425.0
PSMD12 9475.0
TLR1 9536.0
ELOA2 9558.0
RPL23 9567.0
IFNA7 9573.0
H2AC12 9576.0
CTSG 9706.0
IFNA14 9747.0
FXYD6 9870.0
BLNK 9917.0
WIPF3 10005.0
STING1 10015.0
TCEA1 10191.0
IFNA8 10300.0
H2AC17 10569.0
H2BC17 10609.0
MBL2 10726.0
GEMIN2 10747.0
GNGT1 10866.0
TUBB8 10897.0


REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS
594
set REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS
setSize 312
pANOVA 0.000325
s.dist 0.118
p.adjustANOVA 0.041



Top enriched genes

Top 20 genes
GeneID Gene Rank
CCL21 10823
CCL27 10790
CXCL11 10704
XCL2 10629
PROK1 10571
RXFP4 10542
PROKR1 10508
ACKR1 10497
CCL11 10464
CCL2 10462
CCL19 10453
CXCL9 10402
CXCR1 10400
ACKR4 10380
CCL22 10303
MCHR1 10299
RHO 10289
CCL7 10251
FPR1 10222
PRLH 10198

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CCL21 10823
CCL27 10790
CXCL11 10704
XCL2 10629
PROK1 10571
RXFP4 10542
PROKR1 10508
ACKR1 10497
CCL11 10464
CCL2 10462
CCL19 10453
CXCL9 10402
CXCR1 10400
ACKR4 10380
CCL22 10303
MCHR1 10299
RHO 10289
CCL7 10251
FPR1 10222
PRLH 10198
PTGIR 10112
LPAR6 10081
FPR2 9833
NTS 9756
GPHA2 9746
P2RY13 9651
CXCL5 9649
QRFP 9626
AVP 9523
SSTR3 9513
DRD5 9501
MLNR 9417
GPR37L1 9401
HRH1 9375
CCR3 9339
OXGR1 9292
TAAR5 9283
PLPPR4 9275
KNG1 9260
TAC3 9245
CCL16 9166
FSHB 9099
NPB 9095
CCR10 8995
GALR3 8868
CXCR5 8864
EDN1 8786
ACKR3 8779
OPN4 8676
PF4 8616
GPR31 8556
TBXA2R 8554
LPAR5 8539
RRH 8504
CXCL13 8459
FFAR1 8399
AGT 8394
ADRA1D 8295
GPR18 8236
C3AR1 8200
LPAR1 8142
CCRL2 8084
CCR4 8006
TACR2 7958
PLPPR2 7885
EDNRA 7806
CCKAR 7773
GALR1 7653
C5AR2 7612
TAAR9 7574
RXFP2 7518
BDKRB1 7464
PPY 7450
CXCR2 7444
CX3CL1 7433
XCL1 7425
TAAR8 7412
CCL20 7369
HRH2 7044
CX3CR1 7009
APP 6979
LTB4R 6899
RXFP1 6836
P2RY6 6762
CCL5 6673
KEL 6654
HTR1F 6634
HCAR2 6564
CXCL1 6548
NTSR2 6465
MC3R 6318
HCRT 6148
HTR1D 6094
ACKR2 6048
CCR1 5960
FPR3 5938
C5 5885
XCR1 5759
CXCL16 5754
CHRM3 5746
KISS1 5731
ADRB2 5673
C5AR1 5619
MC2R 5615
HTR2A 5588
PRLHR 5562
AGTR1 5444
EDN2 5387
TAAR2 5386
NPSR1 5291
PROK2 5264
HTR1B 5122
F2 5015
RGR 4945
BDKRB2 4929
PSAP 4915
HRH3 4914
SAA1 4861
CCL1 4827
LTB4R2 4780
HTR5A 4749
ADRB3 4643
GAL 4640
CORT 4542
S1PR3 4538
PMCH 4483
NPY 4165
AVPR1B 4019
DRD4 4013
INSL5 3986
GALR2 3941
GPR17 3908
CCR8 3902
NPFFR1 3846
EDN3 3792
CMKLR1 3725
OXER1 3704
PLPPR5 3629
LHB 3546
CCR5 3473
CCL17 3403
TAAR1 3396
HCRTR1 3380
GPR37 3308
NTSR1 3155
CXCL6 3141
LPAR3 3098
HTR7 3082
HTR4 2981
CCL25 2892
PPBP 2850
TACR1 2822
HCAR1 2799
PTGER3 2695
NMS 2506
NLN 2374
P2RY12 2091
KISS1R 2029
NPFFR2 1756
TRHR 1729
TSHB 1626
PTGDR 1512
TSHR 1504
SUCNR1 1231
PTGER2 1100
S1PR2 1076
CCL3 1037
DRD1 1021
MTNR1B 1018
CCR7 1001
P2RY11 984
HTR1E 946
QRFPR 904
PROKR2 893
CXCR6 818
NPS 736
DRD2 659
NPBWR2 644
CHRM5 497
GPR39 434
MC5R 158
CNR1 143
OPRD1 139
GPER1 -1
ADRA1B -142
GPBAR1 -285
PENK -431
P2RY14 -587
PYY -684
PTGER1 -854
F2RL3 -857
ADORA2A -996
GPR68 -1045
CHRM2 -1089
C3 -1115
CNR2 -1324
GPR55 -1390
ADRA2C -1416
ADORA1 -1522
PNOC -1687
HTR6 -1835
MTNR1A -1952
GNRHR -1981
OPRM1 -2020
PDYN -2179
GPHB5 -2191
NPY2R -2224
ECE2 -2305
HEBP1 -2389
OPN3 -2628
ADORA3 -2729
PTGFR -2870
GRP -2947
POMC -3062
GNRH2 -3065
CXCL8 -3101
MC1R -3198
CCR2 -3231
PTAFR -3295
ECE1 -3496
GNRH1 -3608
MLN -3800
PTGER4 -3838
CXCL2 -3874
TACR3 -3919
ADORA2B -4062
NPBWR1 -4112
SST -4116
SSTR5 -4213
CXCL12 -4284
GPR132 -4365
CXCR4 -4374
OXT -4455
CCL28 -4503
FFAR4 -4659
AVPR1A -4743
HRH4 -4758
GPR65 -4785
CCKBR -4855
UTS2B -4895
PLPPR1 -4905
NPFF -4979
FFAR2 -5250
CCL13 -5265
GHSR -5266
OPN5 -5312
MCHR2 -5387
LHCGR -5396
OPRL1 -5510
SSTR2 -5603
F2R -5657
UTS2R -5676
OXTR -5849
GPR35 -6038
APLNR -6124
TAAR6 -6175
S1PR1 -6304
NMB -6377
DRD3 -6496
PTGDR2 -6562
UTS2 -6689
SSTR4 -6776
PLPPR3 -6969
GPR4 -7035
INSL3 -7175
HTR2B -7249
RXFP3 -7397
P2RY1 -7406
FFAR3 -7424
ADRA1A -7568
FSHR -7583
CHRM1 -7639
EDNRB -7684
CGA -7880
ADRB1 -7882
GHRL -8027
F2RL1 -8084
CXCL10 -8093
F2RL2 -8350
CYSLTR2 -8391
OPN1SW -8419
S1PR4 -8632
ADRA2A -8840
ANXA1 -8847
SSTR1 -8925
NPY1R -8972
GPR183 -9116
NPY5R -9125
CHRM4 -9128
CCR6 -9136
S1PR5 -9138
OPRK1 -9324
TRH -9444
P2RY2 -9485
LPAR2 -9569
CCK -9598
ADRA2B -9646
TAC1 -9677
NMUR1 -9759
CCL23 -9803
HTR1A -9929
NMUR2 -9996
NPW -10020
NMU -10034
HCRTR2 -10051
CXCL3 -10102
MC4R -10228
NMBR -10257
RLN3 -10491
CCR9 -10511
RLN2 -10740
CCL4 -11032


REACTOME_GENE_AND_PROTEIN_EXPRESSION_BY_JAK_STAT_SIGNALING_AFTER_INTERLEUKIN_12_STIMULATION

REACTOME_GENE_AND_PROTEIN_EXPRESSION_BY_JAK_STAT_SIGNALING_AFTER_INTERLEUKIN_12_STIMULATION
1306
set REACTOME_GENE_AND_PROTEIN_EXPRESSION_BY_JAK_STAT_SIGNALING_AFTER_INTERLEUKIN_12_STIMULATION
setSize 35
pANOVA 0.000374
s.dist -0.347
p.adjustANOVA 0.0438



Top enriched genes

Top 20 genes
GeneID Gene Rank
GSTA2 -10633
LCP1 -10158
HNRNPF -10055
HNRNPDL -9764
IFNG -9509
RAP1B -8943
PITPNA -8782
STAT4 -8728
ARF1 -8415
PAK2 -7893
GSTO1 -7655
IL10 -7610
ANXA2 -7278
TALDO1 -6537
RPLP0 -6181
MTAP -5945
SERPINB2 -5827
PPIA -4974
AIP -4876
RALA -4253

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GSTA2 -10633
LCP1 -10158
HNRNPF -10055
HNRNPDL -9764
IFNG -9509
RAP1B -8943
PITPNA -8782
STAT4 -8728
ARF1 -8415
PAK2 -7893
GSTO1 -7655
IL10 -7610
ANXA2 -7278
TALDO1 -6537
RPLP0 -6181
MTAP -5945
SERPINB2 -5827
PPIA -4974
AIP -4876
RALA -4253
PSME2 -4065
MIF -3735
CFL1 -2704
HNRNPA2B1 -1410
CNN2 -1371
CAPZA1 -1292
CDC42 -698
SNRPA1 -401
SOD2 1182
PDCD4 1967
LMNB1 4711
SOD1 5985
HSPA9 6756
CA1 6905
TCP1 6937


REACTOME_HIV_INFECTION

REACTOME_HIV_INFECTION
175
set REACTOME_HIV_INFECTION
setSize 223
pANOVA 0.000544
s.dist -0.134
p.adjustANOVA 0.0596



Top enriched genes

Top 20 genes
GeneID Gene Rank
PSMB11 -10777
CDK9 -10699
TPR -10116
UBB -9922
CHMP5 -9794
CD28 -9503
ELOB -9480
SEM1 -9467
MVB12A -9298
APOBEC3G -9198
NUP50 -9137
FEN1 -9104
NCBP1 -8960
TAF9 -8893
PSMD14 -8863
CD247 -8686
RAN -8481
ELOA -8452
ARF1 -8415
SUPT4H1 -8219

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PSMB11 -10777
CDK9 -10699
TPR -10116
UBB -9922
CHMP5 -9794
CD28 -9503
ELOB -9480
SEM1 -9467
MVB12A -9298
APOBEC3G -9198
NUP50 -9137
FEN1 -9104
NCBP1 -8960
TAF9 -8893
PSMD14 -8863
CD247 -8686
RAN -8481
ELOA -8452
ARF1 -8415
SUPT4H1 -8219
NUP42 -8147
XPO1 -8068
TAF6 -8059
PAK2 -7893
B2M -7892
POLR2E -7862
NELFCD -7846
LIG1 -7782
HMGA1 -7648
NUP98 -7640
FURIN -7547
NUP62 -7441
CCNT2 -7423
GTF2H5 -7198
POLR2D -7167
SEH1L -7114
TAF4 -7074
CHMP4C -6983
PSMD9 -6945
NUP160 -6888
TAF2 -6818
GTF2H1 -6694
CHMP2B -6673
NDC1 -6638
TSG101 -6609
SUPT16H -6608
NUP205 -6549
NUP58 -6523
PSMB8 -6491
RAC1 -6469
VPS37D -6347
POLR2H -6221
NUP37 -6122
PSMA8 -6030
NMT1 -5998
RPS27A -5865
PSMD13 -5830
KPNA1 -5788
RANBP1 -5762
CHMP3 -5755
PSME4 -5742
GTF2E1 -5695
RBX1 -5685
PSMD11 -5394
LIG4 -5349
CD4 -5234
PSMB3 -5218
PSIP1 -5188
NUP210 -5101
NUP153 -5090
RANGAP1 -5063
UBAP1 -4994
PPIA -4974
AP2A1 -4922
NUP107 -4906
PDCD6IP -4704
CHMP7 -4660
VPS28 -4654
HLA-A -4587
POLR2B -4576
TAF3 -4447
BANF1 -4441
RNMT -4436
CXCR4 -4374
AP2B1 -4349
CHMP4A -4321
PSMB5 -4259
ELL -4066
PSME2 -4065
PSMD2 -3966
UBC -3937
RCC1 -3906
XRCC6 -3851
SLC25A4 -3772
PSMB4 -3508
PACS1 -3465
NUP43 -3319
NUP35 -3128
PSMD5 -2953
VPS4A -2952
CTDP1 -2893
GTF2A2 -2825
PSMB7 -2811
PSMC5 -2753
AP1S1 -2727
CCNT1 -2694
POLR2J -2572
PSMD3 -2367
NUP214 -2260
NELFE -2161
TAF12 -2056
KPNB1 -2017
NPM1 -1969
AP1M2 -1967
GTF2F1 -1941
CDK7 -1843
PSMD6 -1831
NUP93 -1824
RNGTT -1795
POLR2C -1770
NELFB -1717
CHMP4B -1574
AP1G1 -1501
TAF5 -1384
PSMD7 -1362
ERCC2 -1327
CHMP6 -1065
VPS37A -1028
TBP -894
FYN -804
TAF15 -667
NUP54 -626
CUL5 -510
ELOC -362
PSMA1 -272
BTRC -91
PSME1 -45
PSMC2 97
PSMD1 215
VPS4B 286
ELMO1 331
VTA1 443
NMT2 675
NUP155 699
PSMB6 781
POLR2A 926
POLR2F 952
TAF11 1035
MVB12B 1078
NCBP2 1108
SUPT5H 1279
POM121C 1437
DOCK2 1482
POLR2L 1607
AP1M1 1624
PSMA7 1653
SSRP1 1699
PSMA3 1747
AP1S3 1798
CCNK 1834
PSMA2 1886
NUP188 1951
XRCC4 2316
AP1B1 2617
POM121 2707
SEC13 2762
AP2S1 2792
ATP6V1H 2807
PSMB9 2951
GTF2H3 3037
VPS37C 3048
AP2A2 3233
GTF2B 3312
CCR5 3473
PSMA6 3500
NELFA 3536
AAAS 3650
PSMC6 3773
POLR2K 3831
MNAT1 3936
GTF2H4 4003
RANBP2 4244
GTF2A1 4397
POLR2G 4485
PSME3 4494
PSMC3 4583
AP2M1 4621
TAF4B 4648
PSMB2 4923
VPS37B 4932
TAF1L 4990
ERCC3 5084
NUP85 5382
XRCC5 5400
PSMB1 5472
GTF2F2 5497
PSMC1 5640
CCNH 5718
CHMP2A 5744
PSMD8 5747
TAF13 5751
RAE1 6150
GTF2E2 6307
PSMB10 6504
HCK 6570
LCK 6595
TAF7 7083
PSMA4 7118
PSMD4 7146
NUP133 7196
PSMC4 7533
POLR2I 7727
CD8B 8024
SKP1 8064
PSMA5 8306
NEDD4L 8335
PSMF1 8543
UBA52 8631
NUP88 8810
TAF10 9057
PSMD12 9475
ELOA2 9558
TCEA1 10191


REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT

REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT
214
set REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT
setSize 21
pANOVA 0.000671
s.dist 0.429
p.adjustANOVA 0.0656



Top enriched genes

Top 20 genes
GeneID Gene Rank
FCN1 10907.0
MBL2 10726.0
FCN2 10002.0
C1S 9901.0
FCN3 8996.0
C2 7781.0
MASP2 7399.0
MASP1 6976.0
C4A 6423.5
C4B 6423.5
CFD 6289.0
CRP 6266.0
C1R 5056.0
COLEC11 5005.0
GZMM 4047.0
C1QC 3730.0
C1QB 1606.0
C3 -1115.0
COLEC10 -2489.0
C1QA -6371.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FCN1 10907.0
MBL2 10726.0
FCN2 10002.0
C1S 9901.0
FCN3 8996.0
C2 7781.0
MASP2 7399.0
MASP1 6976.0
C4A 6423.5
C4B 6423.5
CFD 6289.0
CRP 6266.0
C1R 5056.0
COLEC11 5005.0
GZMM 4047.0
C1QC 3730.0
C1QB 1606.0
C3 -1115.0
COLEC10 -2489.0
C1QA -6371.0
CFB -9588.0


REACTOME_SIGNALING_BY_INTERLEUKINS

REACTOME_SIGNALING_BY_INTERLEUKINS
800
set REACTOME_SIGNALING_BY_INTERLEUKINS
setSize 444
pANOVA 0.000679
s.dist -0.094
p.adjustANOVA 0.0656



Top enriched genes

Top 20 genes
GeneID Gene Rank
CCL4 -11032
IFNL1 -10945
PTPN18 -10861
H3C12 -10835
PSMB11 -10777
IL7R -10665
GSTA2 -10633
IL4 -10621
IFNL2 -10444
MCL1 -10433
RORC -10429
LCP1 -10158
IL32 -10135
IL22RA1 -10134
AGER -10061
HNRNPF -10055
STAT5B -10050
PTPN12 -10007
BATF -10006
UBB -9922

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CCL4 -11032.0
IFNL1 -10945.0
PTPN18 -10861.0
H3C12 -10835.0
PSMB11 -10777.0
IL7R -10665.0
GSTA2 -10633.0
IL4 -10621.0
IFNL2 -10444.0
MCL1 -10433.0
RORC -10429.0
LCP1 -10158.0
IL32 -10135.0
IL22RA1 -10134.0
AGER -10061.0
HNRNPF -10055.0
STAT5B -10050.0
PTPN12 -10007.0
BATF -10006.0
UBB -9922.0
DUSP7 -9909.0
INPPL1 -9908.0
IL5RA -9902.0
CASP3 -9798.0
HNRNPDL -9764.0
TGFB1 -9661.0
CEBPD -9648.0
SIGIRR -9529.0
IL13 -9522.0
IFNG -9509.0
SEM1 -9467.0
CNTFR -9421.0
MMP1 -9420.0
H3C7 -9300.5
MAP3K7 -9289.0
IL22 -9261.0
IKBIP -9225.0
IL10RB -9193.0
IL17RB -9165.0
IL2RB -9107.0
RAP1B -8943.0
PSMD14 -8863.0
ANXA1 -8847.0
SYK -8792.0
PITPNA -8782.0
STAT4 -8728.0
H3C1 -8620.0
H3C3 -8519.0
IL12RB2 -8486.0
ARF1 -8415.0
LRRC14 -8374.0
IL36G -8373.0
EBI3 -8344.0
JAK2 -8304.0
ALOX15 -8294.0
PTPN9 -8284.0
RAPGEF1 -8244.0
VEGFA -8125.0
PRKACA -8098.0
IRAK3 -8095.0
CXCL10 -8093.0
CASP1 -7993.0
PAK2 -7893.0
JAK1 -7873.0
YWHAZ -7837.0
CRKL -7832.0
ITGB1 -7812.0
MAPKAPK2 -7786.0
RAG2 -7754.0
VAMP2 -7723.0
GSTO1 -7655.0
IL10 -7610.0
NOD1 -7572.0
MAPK3 -7536.0
TNIP2 -7469.0
MAPK9 -7465.0
YES1 -7425.0
PIM1 -7402.0
MAPK8 -7394.0
HAVCR2 -7391.0
SOCS5 -7360.0
SOCS2 -7339.0
ANXA2 -7278.0
TNFRSF1B -7271.0
HGF -7168.0
IL9 -7148.0
PELI3 -7120.0
RPS6KA5 -7113.0
LGALS9 -7112.0
USP14 -7091.0
IL21 -7053.0
PSMD9 -6945.0
SOCS1 -6887.0
CNTF -6775.0
IL4R -6670.0
FOS -6648.0
IRS2 -6645.0
PPP2CA -6627.0
ATF2 -6615.0
MYC -6612.0
IL12A -6607.0
ICAM1 -6591.0
JUNB -6577.0
MMP9 -6570.0
TALDO1 -6537.0
PSMB8 -6491.0
IL19 -6439.0
ITGB2 -6310.0
S1PR1 -6304.0
IL17RE -6279.0
NKIRAS1 -6228.0
MAPKAPK3 -6188.0
RPLP0 -6181.0
CRK -6052.0
PSMA8 -6030.0
PRTN3 -5965.0
MTAP -5945.0
IL2RA -5866.0
RPS27A -5865.0
CCND1 -5842.0
PSMD13 -5830.0
SERPINB2 -5827.0
IL12RB1 -5822.0
PELI2 -5752.0
PTPN6 -5744.0
PSME4 -5742.0
RBX1 -5685.0
BCL2L1 -5668.0
PTGS2 -5664.0
F13A1 -5595.0
NFKBIB -5528.0
TYK2 -5493.0
SQSTM1 -5484.0
AKT1 -5462.0
STAT1 -5422.0
IL6 -5414.0
PSMD11 -5394.0
IL12B -5296.0
PTPN4 -5241.0
CD4 -5234.0
CSF1 -5233.0
PSMB3 -5218.0
GRB2 -5215.0
JAK3 -5160.0
STAT3 -5158.0
MAPK14 -4997.0
RIPK2 -4991.0
PPIA -4974.0
IL15RA -4880.0
AIP -4876.0
PIK3R1 -4826.0
SDC1 -4818.0
USP18 -4780.0
IKBKB -4657.0
PIK3CD -4566.0
IL27 -4551.0
DUSP3 -4516.0
PTPN23 -4491.0
PIK3CA -4471.0
H3C10 -4463.0
BRWD1 -4435.0
LYN -4414.0
ZEB1 -4371.0
STX1A -4369.0
PTPN2 -4333.0
HSP90B1 -4304.0
PSMB5 -4259.0
RALA -4253.0
CHUK -4148.0
GATA3 -4127.0
PSME2 -4065.0
HMOX1 -3970.0
PSMD2 -3966.0
UBC -3937.0
CXCL2 -3874.0
PTPRZ1 -3819.0
MIF -3735.0
MEF2A -3731.0
TWIST1 -3719.0
IL20RA -3713.0
IL17RA -3660.0
PPP2R5D -3640.0
IL6R -3631.0
PSMB4 -3508.0
TIFA -3462.0
JUN -3450.0
IFNLR1 -3445.0
HMGB1 -3434.0
MAP3K3 -3356.0
NLRC5 -3345.0
PIK3R2 -3341.0
FOXO1 -3310.0
PTAFR -3295.0
MAP2K7 -3285.0
SMARCA4 -3271.0
CASP8 -3233.0
CCR2 -3231.0
TXLNA -3136.0
NFKB1 -3133.0
POU2F1 -3130.0
CXCL8 -3101.0
SOX2 -3095.0
POMC -3062.0
PSMD5 -2953.0
RPS6KA1 -2943.0
IRAK4 -2908.0
PSMB7 -2811.0
PSMC5 -2753.0
CFL1 -2704.0
CANX -2679.0
TRAF2 -2645.0
TEC -2541.0
IL17A -2492.0
BCL6 -2413.0
HSPA8 -2392.0
PSMD3 -2367.0
MAP2K3 -2274.0
IL18RAP -2234.0
OPRM1 -2020.0
TSLP -1950.0
LAMA5 -1946.0
HIF1A -1895.0
PSMD6 -1831.0
NANOG -1796.0
IL17F -1713.0
SOCS3 -1657.0
PTPN14 -1613.0
UBE2N -1518.0
IL20 -1433.0
HNRNPA2B1 -1410.0
CNN2 -1371.0
PSMD7 -1362.0
CAPZA1 -1292.0
MAPK1 -1262.0
LIF -1247.0
IL18R1 -1178.0
IL37 -1139.0
FBXW11 -1101.0
ITGAX -1090.0
ATF1 -1084.0
IL1RN -1077.0
IL31 -1037.0
VAV1 -1031.0
VIM -947.0
FYN -804.0
RORA -778.0
CDC42 -698.0
NFKB2 -677.0
TOLLIP -612.0
IL1R2 -562.0
PIK3R3 -472.0
SNRPA1 -401.0
PSMA1 -272.0
BTRC -91.0
PSME1 -45.0
TBK1 -8.0
IL23R 78.0
PSMC2 97.0
CLCF1 124.0
OPRD1 139.0
IL6ST 144.0
H3C11 151.0
CRLF1 207.0
PSMD1 215.0
IL31RA 268.0
PELI1 343.0
DUSP6 387.0
SOS2 429.0
IL15 461.0
IRF4 563.0
CBL 586.0
TAB1 598.0
BCL2 612.0
RPS6KA2 661.0
TAB2 685.0
PSMB6 781.0
STAT5A 788.0
PPP2R1B 892.0
NFKBIA 1005.0
CCL3 1037.0
PIK3CB 1073.0
FASLG 1154.0
SOD2 1182.0
MAP2K6 1198.0
PTK2B 1214.0
PTPN13 1353.0
CISH 1406.0
STX3 1553.0
MAP3K8 1562.0
IL11RA 1572.0
PSMA7 1653.0
IL1B 1688.0
PSMA3 1747.0
GSDMD 1786.0
IL33 1873.0
PSMA2 1886.0
MEF2C 1924.0
PDCD4 1967.0
IL22RA2 1979.0
RHOU 2009.0
BIRC5 2072.0
MAPK10 2096.0
TRAF6 2148.0
FSCN1 2262.0
IL21R 2434.0
CSF2RB 2536.0
CD36 2576.0
RELA 2577.0
NOD2 2618.0
MYD88 2621.0
CD86 2662.0
RAG1 2737.0
IL18BP 2766.0
CDKN1A 2787.0
CREB1 2805.0
MAPK11 2820.0
ALOX5 2821.0
OSMR 2858.0
LIFR 2936.0
PSMB9 2951.0
IL1RAP 2968.0
IL24 2980.0
DUSP4 3211.0
P4HB 3386.0
SMAD3 3457.0
CCR5 3473.0
PSMA6 3500.0
STXBP2 3580.0
PSMC6 3773.0
STX4 3883.0
OSM 3931.0
ITGAM 4342.0
NOS2 4447.0
PTPN7 4448.0
PSME3 4494.0
IRS1 4535.0
IL27RA 4541.0
FN1 4581.0
PSMC3 4583.0
LMNB1 4711.0
SHC1 4832.0
SAA1 4861.0
PSMB2 4923.0
IL17RC 5082.0
SNAP25 5090.0
IL1RL1 5172.0
IRAK2 5182.0
MAP2K1 5187.0
INPP5D 5405.0
PSMB1 5472.0
IL25 5496.0
MAP2K4 5503.0
IL36RN 5522.0
CUL1 5560.0
PSMC1 5640.0
GAB2 5678.0
PSMD8 5747.0
FGF2 5798.0
H3C8 5831.0
CCR1 5960.0
SOD1 5985.0
TNF 6076.0
N4BP1 6108.0
MMP2 6110.0
COL1A2 6208.0
NLRX1 6255.0
S100B 6364.0
IL10RA 6441.0
NKIRAS2 6479.0
IL2 6486.0
PSMB10 6504.0
CXCL1 6548.0
IL1R1 6554.0
HCK 6570.0
LCK 6595.0
UBE2V1 6602.0
HSP90AA1 6611.0
FOXO3 6649.0
CCL5 6673.0
IL1RL2 6685.0
HSPA9 6756.0
STAT6 6778.0
TP53 6860.0
CA1 6905.0
TCP1 6937.0
APP 6979.0
PSMA4 7118.0
VRK3 7130.0
PSMD4 7146.0
TNFRSF1A 7280.0
H3C4 7300.0
IL18 7335.0
CCL20 7369.0
IL17C 7521.0
PSMC4 7533.0
SOS1 7541.0
H3C6 7676.0
VCAM1 7681.0
CTF1 7744.0
NDN 7775.0
IL16 7865.0
IL5 7870.0
SKP1 8064.0
ALPK1 8105.0
MMP3 8214.0
H3C2 8265.0
IL7 8285.0
PSMA5 8306.0
IL26 8475.0
IL20RB 8502.0
CD80 8508.0
IL11 8528.0
PSMF1 8543.0
MAPK7 8612.0
UBA52 8631.0
MUC1 8790.0
IL1A 8830.0
PTPN11 8872.0
STAT2 9014.0
PPP2R1A 9244.0
IL36B 9290.0
PPP2CB 9331.0
CSF3 9384.0
PTPN5 9387.0
IL1F10 9447.0
PSMD12 9475.0
CSF3R 9499.0
FCER2 9527.0
CSF1R 9655.0
CTSG 9706.0
IL23A 9719.0
LBP 9796.0
IL34 9811.0
BLNK 9917.0
IL36A 9963.0
IL3 10126.0
LCN2 10186.0
FPR1 10222.0
CCL22 10303.0
S100A12 10306.0
CCL19 10453.0
CCL2 10462.0
CCL11 10464.0
CSF2 10602.0


REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS

REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS
216
set REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS
setSize 14
pANOVA 0.000973
s.dist 0.509
p.adjustANOVA 0.0888



Top enriched genes

Top 20 genes
GeneID Gene Rank
FCN1 10907
MBL2 10726
FCN2 10002
C1S 9901
FCN3 8996
MASP2 7399
MASP1 6976
CRP 6266
C1R 5056
COLEC11 5005
C1QC 3730
C1QB 1606
COLEC10 -2489
C1QA -6371

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FCN1 10907
MBL2 10726
FCN2 10002
C1S 9901
FCN3 8996
MASP2 7399
MASP1 6976
CRP 6266
C1R 5056
COLEC11 5005
C1QC 3730
C1QB 1606
COLEC10 -2489
C1QA -6371


REACTOME_NGF_STIMULATED_TRANSCRIPTION

REACTOME_NGF_STIMULATED_TRANSCRIPTION
1422
set REACTOME_NGF_STIMULATED_TRANSCRIPTION
setSize 38
pANOVA 0.00114
s.dist -0.305
p.adjustANOVA 0.0987



Top enriched genes

Top 20 genes
GeneID Gene Rank
ARC -10482
SRF -10256
CDK5R1 -9822
FOSB -8252
ASCL1 -8241
TRIB1 -7816
ID3 -6813
TPH1 -6659
FOS -6648
ATF2 -6615
JUNB -6577
JUND -6426
EP300 -6367
NAB2 -6323
LYL1 -5411
EGR3 -5056
RRAD -4986
F3 -4507
DNM2 -4245
MEF2D -3575

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ARC -10482
SRF -10256
CDK5R1 -9822
FOSB -8252
ASCL1 -8241
TRIB1 -7816
ID3 -6813
TPH1 -6659
FOS -6648
ATF2 -6615
JUNB -6577
JUND -6426
EP300 -6367
NAB2 -6323
LYL1 -5411
EGR3 -5056
RRAD -4986
F3 -4507
DNM2 -4245
MEF2D -3575
EGR4 -2970
NAB1 -2431
TCF12 -2412
EGR2 -2402
CDK5 -2184
ATF1 -1084
SGK1 -637
ID1 -535
CHD4 -474
EGR1 232
ID4 595
CDK5R2 884
FOSL1 1898
ID2 1912
SH3GL3 2522
CREB1 2805
VGF 4029
REST 6265


REACTOME_LECTIN_PATHWAY_OF_COMPLEMENT_ACTIVATION

REACTOME_LECTIN_PATHWAY_OF_COMPLEMENT_ACTIVATION
213
set REACTOME_LECTIN_PATHWAY_OF_COMPLEMENT_ACTIVATION
setSize 8
pANOVA 0.00127
s.dist 0.658
p.adjustANOVA 0.104



Top enriched genes

Top 20 genes
GeneID Gene Rank
FCN1 10907
MBL2 10726
FCN2 10002
FCN3 8996
MASP2 7399
MASP1 6976
COLEC11 5005
COLEC10 -2489

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FCN1 10907
MBL2 10726
FCN2 10002
FCN3 8996
MASP2 7399
MASP1 6976
COLEC11 5005
COLEC10 -2489


REACTOME_ASPIRIN_ADME

REACTOME_ASPIRIN_ADME
1595
set REACTOME_ASPIRIN_ADME
setSize 42
pANOVA 0.00168
s.dist 0.28
p.adjustANOVA 0.127



Top enriched genes

Top 20 genes
GeneID Gene Rank
ACSM2B 10724
UGT2A3 10465
ACSM2A 10379
ACSM5 10304
ACSM4 10158
ABCC2 10045
UGT2B15 9949
GLYAT 9669
UGT3A2 9507
GLYATL2 9504
CES1 9219
UGT1A9 8737
UGT1A6 8640
UGT1A7 8537
UGT1A8 8337
CYP2C9 8085
GLYATL1 7831
UGT3A1 7471
CYP2D6 7459
SLCO2B1 5601

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ACSM2B 10724
UGT2A3 10465
ACSM2A 10379
ACSM5 10304
ACSM4 10158
ABCC2 10045
UGT2B15 9949
GLYAT 9669
UGT3A2 9507
GLYATL2 9504
CES1 9219
UGT1A9 8737
UGT1A6 8640
UGT1A7 8537
UGT1A8 8337
CYP2C9 8085
GLYATL1 7831
UGT3A1 7471
CYP2D6 7459
SLCO2B1 5601
CES2 5185
UGT2B11 5037
UGT1A5 4615
CYP2C19 4150
CYP2E1 3024
UGT1A4 2165
ABCC3 2112
SLC22A7 1012
UGT1A3 495
CYP3A4 -1844
SLC16A1 -1848
CYP2C8 -3664
UGT2B7 -4511
UGT2A2 -5475
UGT2B17 -5954
UGT2A1 -6072
UGT1A1 -6924
GLYATL3 -7966
ALB -8513
UGT2B4 -8626
BCHE -9512
BSG -10255


REACTOME_FICOLINS_BIND_TO_REPETITIVE_CARBOHYDRATE_STRUCTURES_ON_THE_TARGET_CELL_SURFACE

REACTOME_FICOLINS_BIND_TO_REPETITIVE_CARBOHYDRATE_STRUCTURES_ON_THE_TARGET_CELL_SURFACE
521
set REACTOME_FICOLINS_BIND_TO_REPETITIVE_CARBOHYDRATE_STRUCTURES_ON_THE_TARGET_CELL_SURFACE
setSize 5
pANOVA 0.00172
s.dist 0.809
p.adjustANOVA 0.127



Top enriched genes

Top 20 genes
GeneID Gene Rank
FCN1 10907
FCN2 10002
FCN3 8996
MASP2 7399
MASP1 6976

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FCN1 10907
FCN2 10002
FCN3 8996
MASP2 7399
MASP1 6976


REACTOME_COMPLEMENT_CASCADE

REACTOME_COMPLEMENT_CASCADE
212
set REACTOME_COMPLEMENT_CASCADE
setSize 54
pANOVA 0.00178
s.dist 0.246
p.adjustANOVA 0.127



Top enriched genes

Top 20 genes
GeneID Gene Rank
FCN1 10907.0
CFHR2 10804.0
MBL2 10726.0
ELANE 10392.0
CPN1 10159.0
CFI 10064.0
FCN2 10002.0
C1S 9901.0
FCN3 8996.0
C4BPB 8771.0
C3AR1 8200.0
C2 7781.0
C5AR2 7612.0
CPN2 7409.0
MASP2 7399.0
CFHR4 7025.0
MASP1 6976.0
C4A 6423.5
C4B 6423.5
CFD 6289.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FCN1 10907.0
CFHR2 10804.0
MBL2 10726.0
ELANE 10392.0
CPN1 10159.0
CFI 10064.0
FCN2 10002.0
C1S 9901.0
FCN3 8996.0
C4BPB 8771.0
C3AR1 8200.0
C2 7781.0
C5AR2 7612.0
CPN2 7409.0
MASP2 7399.0
CFHR4 7025.0
MASP1 6976.0
C4A 6423.5
C4B 6423.5
CFD 6289.0
CRP 6266.0
C5 5885.0
C5AR1 5619.0
C6 5066.0
C1R 5056.0
F2 5015.0
COLEC11 5005.0
GZMM 4047.0
SERPING1 3804.0
C1QC 3730.0
CD46 3495.0
PROS1 3463.0
CR1 2759.0
C9 2706.0
CD55 1754.0
C1QB 1606.0
CPB2 936.0
C8B -186.0
C3 -1115.0
CFHR5 -1753.0
C7 -2321.0
CR2 -2427.0
COLEC10 -2489.0
CLU -4134.0
CFH -5282.0
C1QA -6371.0
C8A -6622.0
CD19 -6883.0
CD59 -8390.0
C8G -8790.0
VTN -9157.0
C4BPA -9520.0
CFB -9588.0
CD81 -10300.0


REACTOME_CELLULAR_SENESCENCE

REACTOME_CELLULAR_SENESCENCE
503
set REACTOME_CELLULAR_SENESCENCE
setSize 189
pANOVA 0.00185
s.dist -0.131
p.adjustANOVA 0.127



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2AC14 -10913.0
H3C12 -10835.0
H2BC14 -10763.0
CCNE1 -10562.0
ERF -10340.0
CEBPB -10333.0
H4C9 -10310.0
H2AC20 -10156.0
MIR24-2 -10078.0
H1-5 -9954.0
UBE2S -9950.0
UBB -9922.0
H1-4 -9916.0
CCNE2 -9892.0
ASF1A -9714.0
H2BC3 -9544.0
EZH2 -9507.0
FZR1 -9437.0
H2BC9 -9300.5
H3C7 -9300.5

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2AC14 -10913.0
H3C12 -10835.0
H2BC14 -10763.0
CCNE1 -10562.0
ERF -10340.0
CEBPB -10333.0
H4C9 -10310.0
H2AC20 -10156.0
MIR24-2 -10078.0
H1-5 -9954.0
UBE2S -9950.0
UBB -9922.0
H1-4 -9916.0
CCNE2 -9892.0
ASF1A -9714.0
H2BC3 -9544.0
EZH2 -9507.0
FZR1 -9437.0
H2BC9 -9300.5
H3C7 -9300.5
ANAPC2 -8906.0
H3C1 -8620.0
H3C3 -8519.0
ETS1 -8439.0
H4C16 -8404.0
H2BC21 -8354.0
CBX4 -8266.0
MDM2 -8204.0
PHC1 -7936.0
CDKN2C -7847.0
KAT5 -7841.0
H4C12 -7830.0
MAPKAPK2 -7786.0
NBN -7749.0
HMGA1 -7648.0
MAPK3 -7536.0
TINF2 -7527.0
MAPK9 -7465.0
MAPKAPK5 -7410.0
MAPK8 -7394.0
ETS2 -7342.0
RING1 -7179.0
H3-3B -7000.0
AGO4 -6874.0
CDK6 -6846.0
CDC16 -6705.0
FOS -6648.0
H1-0 -6533.0
ACD -6355.5
CABIN1 -6215.0
MAPKAPK3 -6188.0
H2BC15 -6116.0
MINK1 -5893.0
RPS27A -5865.0
ANAPC7 -5847.0
H2BC26 -5544.0
IL6 -5414.0
CDC23 -5346.0
TNRC6A -5305.0
STAT3 -5158.0
MAPK14 -4997.0
TERF2 -4976.0
BMI1 -4742.0
TERF2IP -4691.0
CDKN2A -4653.0
H2AC18 -4497.5
H2AC19 -4497.5
H3C10 -4463.0
MAP3K5 -4292.0
H3-3A -4272.0
H1-1 -4143.0
H2BC12 -4085.0
SP1 -4003.0
UBC -3937.0
RAD50 -3822.0
ANAPC5 -3480.0
JUN -3450.0
H4C11 -3297.0
MAP2K7 -3285.0
MIR24-1 -3245.0
NFKB1 -3133.0
CXCL8 -3101.0
UBE2E1 -3038.0
H2AZ2 -3002.0
RPS6KA1 -2943.0
H2AC6 -2934.0
E2F3 -2925.0
PHC3 -2907.0
TNRC6B -2859.0
H4C1 -2748.0
CDK2 -2703.0
MAP2K3 -2274.0
CBX6 -2079.0
H4C13 -1989.0
EHMT1 -1982.0
H4C6 -1963.0
TERF1 -1904.0
CDKN1B -1705.0
TFDP2 -1654.0
CCNA1 -1611.0
H4C3 -1564.0
ANAPC1 -1451.0
MAPK1 -1262.0
ANAPC16 -1202.0
MDM4 -1010.0
CDC26 -850.0
EP400 -836.0
KDM6B -760.0
E2F1 -730.0
HMGA2 -537.0
ID1 -535.0
PHC2 -374.0
MAP4K4 -153.0
CBX2 -124.0
H3C11 151.0
ANAPC11 264.0
IGFBP7 289.0
E2F2 403.0
RPS6KA2 661.0
VENTX 900.0
MAP2K6 1198.0
EED 1280.0
TNIK 1320.0
MOV10 1527.0
IFNB1 2004.0
TFDP1 2022.0
MAPK10 2096.0
H4C5 2140.0
ANAPC4 2282.0
AGO3 2357.0
CDK4 2457.0
H2AC8 2496.0
RELA 2577.0
CCNA2 2601.0
H2AC7 2644.5
H2BC7 2644.5
ANAPC10 2777.0
CDKN1A 2787.0
H2AZ1 2788.0
MAPK11 2820.0
ATM 2903.0
H4C2 3043.0
H2BC4 3069.0
RNF2 3421.0
H2BC1 3439.0
TXN 3461.0
AGO1 3563.0
H2BC10 3582.0
ANAPC15 3810.0
POT1 4143.0
H4C4 4495.0
H2BC5 4649.0
LMNB1 4711.0
H2BC11 4747.0
H2BC13 4779.0
H4C8 5287.0
EHMT2 5380.0
HIRA 5494.0
MAP2K4 5503.0
MRE11 5638.0
CDKN2B 5662.0
H2AX 5736.0
H3C8 5831.0
RBBP4 6098.0
UBE2D1 6123.0
UBE2C 6168.0
TNRC6C 6460.0
H2AJ 6509.0
CDKN2D 6758.0
SUZ12 6827.0
TP53 6860.0
H2BC8 7037.0
UBN1 7058.0
H2BC6 7179.0
H3C4 7300.0
CBX8 7655.0
H3C6 7676.0
H1-2 7807.0
RB1 7828.0
SCMH1 7900.0
H1-3 7959.0
H3C2 8265.0
CDC27 8270.0
MAPK7 8612.0
UBA52 8631.0
IL1A 8830.0
H3-4 9296.0
H2AC4 9304.0
H2BC17 10609.0


REACTOME_SIGNALING_BY_NTRKS

REACTOME_SIGNALING_BY_NTRKS
211
set REACTOME_SIGNALING_BY_NTRKS
setSize 132
pANOVA 0.00203
s.dist -0.156
p.adjustANOVA 0.132



Top enriched genes

Top 20 genes
GeneID Gene Rank
ARC -10482
NRAS -10476
SRF -10256
DUSP7 -9909
PLCG1 -9896
CDK5R1 -9822
MAPK13 -9236
RALB -8375
BRAF -8327
FOSB -8252
RAPGEF1 -8244
ASCL1 -8241
KRAS -7961
CRKL -7832
TRIB1 -7816
MAPKAPK2 -7786
HRAS -7726
FURIN -7547
MAPK3 -7536
BAX -7368

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ARC -10482
NRAS -10476
SRF -10256
DUSP7 -9909
PLCG1 -9896
CDK5R1 -9822
MAPK13 -9236
RALB -8375
BRAF -8327
FOSB -8252
RAPGEF1 -8244
ASCL1 -8241
KRAS -7961
CRKL -7832
TRIB1 -7816
MAPKAPK2 -7786
HRAS -7726
FURIN -7547
MAPK3 -7536
BAX -7368
RPS6KA5 -7113
NTRK1 -6882
ID3 -6813
TPH1 -6659
FOS -6648
IRS2 -6645
PPP2CA -6627
ATF2 -6615
JUNB -6577
RAC1 -6469
JUND -6426
EP300 -6367
NAB2 -6323
RALGDS -6305
SHC2 -6292
MAPKAPK3 -6188
CRK -6052
LYL1 -5411
GRB2 -5215
STAT3 -5158
EGR3 -5056
ADCYAP1 -5055
MAPK14 -4997
RRAD -4986
AP2A1 -4922
PIK3R1 -4826
RAP1A -4713
DUSP3 -4516
F3 -4507
PIK3CA -4471
AP2B1 -4349
MAP2K5 -4343
YWHAB -4317
FRS2 -4288
RALA -4253
DNM2 -4245
FRS3 -3850
MEF2A -3731
PPP2R5D -3640
MEF2D -3575
PIK3R2 -3341
EGR4 -2970
RPS6KA1 -2943
SH3GL2 -2924
CLTC -2818
RIT2 -2591
NAB1 -2431
TCF12 -2412
EGR2 -2402
CDK5 -2184
TIAM1 -1932
DOCK3 -1836
NELFB -1717
GRIN2B -1631
MAPK1 -1262
ATF1 -1084
ADORA2A -996
FYN -804
SGK1 -637
ID1 -535
CHD4 -474
ADCYAP1R1 -371
KIDINS220 57
EGR1 232
PTPRS 316
DUSP6 387
MAPK12 447
ID4 595
RPS6KA2 661
BDNF 723
CDK5R2 884
PPP2R1B 892
PIK3CB 1073
PTPRO 1080
CLTA 1840
DNAL4 1856
FOSL1 1898
ID2 1912
MEF2C 1924
SHC3 2436
SH3GL3 2522
AP2S1 2792
CREB1 2805
MAPK11 2820
NTRK3 2947
DUSP4 3211
AP2A2 3233
GAB1 3643
VGF 4029
RHOA 4216
NTRK2 4232
IRS1 4535
AP2M1 4621
SHC1 4832
NGF 4888
MAP2K1 5187
DNM3 5449
PCSK5 5709
NTF4 5989
REST 6265
MAP2K2 6535
RIT1 6593
NTF3 6774
SRC 7032
VRK3 7130
SOS1 7541
PCSK6 7710
MAPK7 8612
PTPN11 8872
PPP2R1A 9244
PPP2CB 9331
DNM1 9498


REACTOME_SIGNALING_BY_ERYTHROPOIETIN

REACTOME_SIGNALING_BY_ERYTHROPOIETIN
1354
set REACTOME_SIGNALING_BY_ERYTHROPOIETIN
setSize 25
pANOVA 0.00216
s.dist -0.354
p.adjustANOVA 0.132



Top enriched genes

Top 20 genes
GeneID Gene Rank
NRAS -10476
STAT5B -10050
PLCG1 -9896
EPOR -9637
JAK2 -8304
RAPGEF1 -8244
KRAS -7961
CRKL -7832
HRAS -7726
IRS2 -6645
PLCG2 -6119
GRB2 -5215
PIK3R1 -4826
PIK3CD -4566
PIK3CA -4471
LYN -4414
PIK3R5 -3852
PIK3CG -3094
VAV1 -1031
STAT5A 788

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NRAS -10476
STAT5B -10050
PLCG1 -9896
EPOR -9637
JAK2 -8304
RAPGEF1 -8244
KRAS -7961
CRKL -7832
HRAS -7726
IRS2 -6645
PLCG2 -6119
GRB2 -5215
PIK3R1 -4826
PIK3CD -4566
PIK3CA -4471
LYN -4414
PIK3R5 -3852
PIK3CG -3094
VAV1 -1031
STAT5A 788
PIK3CB 1073
GAB1 3643
SHC1 4832
SOS1 7541
EPO 7935


REACTOME_THE_CANONICAL_RETINOID_CYCLE_IN_RODS_TWILIGHT_VISION

REACTOME_THE_CANONICAL_RETINOID_CYCLE_IN_RODS_TWILIGHT_VISION
489
set REACTOME_THE_CANONICAL_RETINOID_CYCLE_IN_RODS_TWILIGHT_VISION
setSize 23
pANOVA 0.00217
s.dist 0.369
p.adjustANOVA 0.132



Top enriched genes

Top 20 genes
GeneID Gene Rank
RBP3 10677
RHO 10289
TTR 10144
RPE65 9789
SDR9C7 9394
RLBP1 9332
HSD17B1 8968
RDH12 8111
STRA6 7160
RDH8 6990
ABCA4 6270
RDH11 5643
DHRS9 5286
RDH10 5089
RDH16 4868
MYO7A 4512
CYP4V2 4118
HSD17B6 128
RDH5 -4076
LRAT -6073

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RBP3 10677
RHO 10289
TTR 10144
RPE65 9789
SDR9C7 9394
RLBP1 9332
HSD17B1 8968
RDH12 8111
STRA6 7160
RDH8 6990
ABCA4 6270
RDH11 5643
DHRS9 5286
RDH10 5089
RDH16 4868
MYO7A 4512
CYP4V2 4118
HSD17B6 128
RDH5 -4076
LRAT -6073
RBP4 -6512
RBP1 -8536
NAPEPLD -9312


REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION

REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION
625
set REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION
setSize 81
pANOVA 0.00227
s.dist -0.196
p.adjustANOVA 0.133



Top enriched genes

Top 20 genes
GeneID Gene Rank
CEBPB -10333
MED9 -10029
MED16 -9698
CCNC -9662
TGFB1 -9661
CEBPD -9648
ADIRF -8899
PPARA -8731
MED31 -8074
THRAP3 -8056
SREBF2 -8046
MED25 -8011
PPARGC1A -7933
CEBPA -7690
NCOA6 -7664
CHD9 -7457
PPARG -7299
MED21 -7266
ZNF467 -7220
PCK1 -7123

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CEBPB -10333
MED9 -10029
MED16 -9698
CCNC -9662
TGFB1 -9661
CEBPD -9648
ADIRF -8899
PPARA -8731
MED31 -8074
THRAP3 -8056
SREBF2 -8046
MED25 -8011
PPARGC1A -7933
CEBPA -7690
NCOA6 -7664
CHD9 -7457
PPARG -7299
MED21 -7266
ZNF467 -7220
PCK1 -7123
PLIN1 -6968
KLF4 -6565
TBL1XR1 -6448
EP300 -6367
MED13L -6324
LEP -6237
MED4 -5949
KLF5 -5915
MED20 -5824
MED22 -5259
WNT10B -4405
TGS1 -4373
HELZ2 -4131
MED13 -4095
WNT1 -4015
MED23 -3771
MED1 -3252
NFKB1 -3133
NR2F2 -3024
NCOA2 -2571
CDK8 -2485
MED17 -2452
EGR2 -2402
CCND3 -2300
MED29 -1794
MED15 -1615
SLC2A4 -1492
MED8 -1489
MED10 -1281
FABP4 -1234
CARM1 -961
SREBF1 -849
HDAC3 -661
CREBBP -600
MED18 -314
FAM120B -278
ZNF638 82
CDK19 223
EBF1 856
LPL 864
NCOA3 1539
CDK4 2457
CD36 2576
RELA 2577
NCOA1 2974
MED28 3307
NCOR2 3341
NCOR1 3553
MED26 3965
MED27 5524
SMARCD3 5704
TNF 6076
MED7 6343
MED11 6389
MED30 6490
MED6 6743
RXRA 6789
MED24 7023
MED19 7405
ANGPTL4 8464
ADIPOQ 10087


REACTOME_HCMV_INFECTION

REACTOME_HCMV_INFECTION
1463
set REACTOME_HCMV_INFECTION
setSize 152
pANOVA 0.00243
s.dist -0.142
p.adjustANOVA 0.137



Top enriched genes

Top 20 genes
GeneID Gene Rank
TUBA3D -10927.0
H2AC14 -10913.0
H3C12 -10835.0
H2BC14 -10763.0
H4C9 -10310.0
H2AC20 -10156.0
TPR -10116.0
TUBB4A -9800.0
CEBPD -9648.0
H2BC3 -9544.0
EZH2 -9507.0
H2BC9 -9300.5
H3C7 -9300.5
MVB12A -9298.0
TUBB1 -9184.0
NUP50 -9137.0
H3C1 -8620.0
TRIM28 -8551.0
H3C3 -8519.0
H2AC15 -8462.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TUBA3D -10927.0
H2AC14 -10913.0
H3C12 -10835.0
H2BC14 -10763.0
H4C9 -10310.0
H2AC20 -10156.0
TPR -10116.0
TUBB4A -9800.0
CEBPD -9648.0
H2BC3 -9544.0
EZH2 -9507.0
H2BC9 -9300.5
H3C7 -9300.5
MVB12A -9298.0
TUBB1 -9184.0
NUP50 -9137.0
H3C1 -8620.0
TRIM28 -8551.0
H3C3 -8519.0
H2AC15 -8462.0
H4C16 -8404.0
H2BC21 -8354.0
NUP42 -8147.0
H4C12 -7830.0
ITGB1 -7812.0
TUBAL3 -7714.0
NUP98 -7640.0
NUP62 -7441.0
SNF8 -7369.0
H2AC16 -7367.0
SEH1L -7114.0
TUBB2B -7059.0
GPS2 -7024.0
CHMP4C -6983.0
NUP160 -6888.0
CHMP2B -6673.0
NDC1 -6638.0
TSG101 -6609.0
NUP205 -6549.0
NUP58 -6523.0
TBL1XR1 -6448.0
VPS37D -6347.0
TUBB2A -6285.0
NUP37 -6122.0
H2BC15 -6116.0
CHMP3 -5755.0
H2BC26 -5544.0
TUBA1B -5322.0
NUP210 -5101.0
NUP153 -5090.0
UBAP1 -4994.0
H2AC25 -4934.0
NUP107 -4906.0
CBX1 -4768.0
CHMP7 -4660.0
VPS28 -4654.0
DYNC1I1 -4614.0
H2AC18 -4497.5
H2AC19 -4497.5
H3C10 -4463.0
DYNC1LI1 -4424.0
CHMP4A -4321.0
PML -4271.0
H2BC12 -4085.0
TUBA8 -3728.0
TUBB4B -3663.0
DYNLL1 -3346.0
NUP43 -3319.0
H4C11 -3297.0
NFKB1 -3133.0
NUP35 -3128.0
VPS4A -2952.0
H2AC6 -2934.0
H4C1 -2748.0
DYNC1I2 -2526.0
NUP214 -2260.0
CHMP1A -2099.0
EGFR -2039.0
H4C13 -1989.0
H4C6 -1963.0
NUP93 -1824.0
CHMP4B -1574.0
H4C3 -1564.0
H2AC1 -1303.0
HNRNPK -1207.0
CHMP6 -1065.0
VPS37A -1028.0
HDAC3 -661.0
NUP54 -626.0
DYNLL2 -501.0
TUBA1C -435.0
TUBB3 -380.0
TUBA3C -228.0
TUBA1A 53.0
H3C11 151.0
NUP155 699.0
DYNC1H1 1000.0
MVB12B 1078.0
EED 1280.0
POM121C 1437.0
DAXX 1511.0
VPS36 1822.0
NUP188 1951.0
H4C5 2140.0
H2AC8 2496.0
H2AC7 2644.5
H2BC7 2644.5
POM121 2707.0
SEC13 2762.0
CREB1 2805.0
H2AC21 3029.0
H4C2 3043.0
VPS37C 3048.0
H2BC4 3069.0
NCOR2 3341.0
DYNC1LI2 3368.0
H2BC1 3439.0
NCOR1 3553.0
H2BC10 3582.0
AAAS 3650.0
TUBA4B 3701.0
H2AC13 4182.0
RANBP2 4244.0
H4C4 4495.0
TUBA3E 4513.0
H2BC5 4649.0
H2BC11 4747.0
H2BC13 4779.0
VPS37B 4932.0
H4C8 5287.0
TUBA4A 5381.0
NUP85 5382.0
CHMP2A 5744.0
H3C8 5831.0
RBBP4 6098.0
RAE1 6150.0
VPS25 6462.0
TUBB6 6645.0
SUZ12 6827.0
H2BC8 7037.0
H2BC6 7179.0
NUP133 7196.0
H3C4 7300.0
H3C6 7676.0
H2AC11 8172.0
H3C2 8265.0
NUP88 8810.0
H2AC4 9304.0
H2AC12 9576.0
H2AC17 10569.0
H2BC17 10609.0
TUBB8 10897.0


REACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53

REACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53
591
set REACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53
setSize 351
pANOVA 0.0026
s.dist -0.0936
p.adjustANOVA 0.142



Top enriched genes

Top 20 genes
GeneID Gene Rank
CDK9 -10699
CCNE1 -10562
ING2 -10117
LAMTOR1 -9994
UBB -9922
CCNE2 -9892
CDK5R1 -9822
ATRIP -9818
EXO1 -9739
APAF1 -9589
ELOB -9480
BBC3 -9427
RRAGA -9391
CCNG1 -9315
MLST8 -9295
STK11 -9278
COX14 -9239
LRPPRC -9237
MEAF6 -9033
PRELID1 -9019

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CDK9 -10699
CCNE1 -10562
ING2 -10117
LAMTOR1 -9994
UBB -9922
CCNE2 -9892
CDK5R1 -9822
ATRIP -9818
EXO1 -9739
APAF1 -9589
ELOB -9480
BBC3 -9427
RRAGA -9391
CCNG1 -9315
MLST8 -9295
STK11 -9278
COX14 -9239
LRPPRC -9237
MEAF6 -9033
PRELID1 -9019
TAF9 -8893
PRKAG1 -8870
PIN1 -8800
ARID3A -8653
CASP6 -8617
ELOA -8452
MBD3 -8372
PLK3 -8356
SUPT4H1 -8219
MDM2 -8204
GPI -8123
TAF6 -8059
LAMTOR5 -8042
CASP1 -7993
LAMTOR4 -7977
HDAC1 -7942
PDPK1 -7939
POLR2E -7862
NELFCD -7846
KAT5 -7841
DDB2 -7840
YWHAZ -7837
RPA2 -7819
COX4I1 -7799
NBN -7749
FAS -7592
AURKB -7569
RBL2 -7486
SCO1 -7450
CCNT2 -7423
MAPKAPK5 -7410
BAX -7368
MLH1 -7292
SESN3 -7246
DYRK2 -7214
GTF2H5 -7198
POLR2D -7167
BRPF1 -7160
TAF4 -7074
MTA2 -6980
AGO4 -6874
RICTOR -6853
TAF2 -6818
PRDX2 -6800
CNOT7 -6797
CSNK2A2 -6773
PERP -6717
GTF2H1 -6694
FOS -6648
RAD17 -6642
PPP2CA -6627
RPA1 -6619
ATF2 -6615
SUPT16H -6608
NDUFA4 -6560
PLK2 -6539
BRD1 -6417
COX8A -6387
EP300 -6367
CDK13 -6284
POLR2H -6221
PPP2R5C -6138
TTC5 -6077
RABGGTA -5997
RPS27A -5865
SURF1 -5836
POU4F2 -5763
TP53INP1 -5714
CNOT6L -5548
RFC2 -5485
AKT1 -5462
RABGGTB -5341
RRAGC -5327
TNRC6A -5305
PIP4K2B -5303
RAD1 -5203
SCO2 -5150
PPP1R13L -5149
CSNK2B -5093
TACO1 -5086
MAPK14 -4997
GSR -4975
RHEB -4892
E2F7 -4887
RGCC -4878
PRDX5 -4847
PRKAA2 -4688
CDKN2A -4653
POLR2B -4576
BARD1 -4531
COX20 -4501
TSC2 -4482
TAF3 -4447
COX19 -4420
LAMTOR2 -4357
YWHAB -4317
TP53I3 -4273
PML -4271
COX7A2L -4201
RRM2B -4155
WRN -4082
ELL -4066
AKT2 -4008
PTEN -3951
UBC -3937
AGO2 -3870
RAD50 -3822
HUS1 -3650
PIP4K2A -3648
KAT6A -3565
CCNB1 -3520
TOP3A -3494
COX11 -3478
JUN -3450
TP53RK -3438
SLC38A9 -3401
CASP2 -3281
TPX2 -3261
CNOT9 -3044
COX6A1 -3025
RRAGD -3003
CTDP1 -2893
RFC5 -2867
TNRC6B -2859
RFC4 -2759
CNOT11 -2721
USP2 -2718
CDK2 -2703
CCNT1 -2694
CNOT8 -2632
HIPK1 -2598
POLR2J -2572
BCL6 -2413
IGFBP3 -2391
BRPF3 -2326
BLM -2275
AIFM2 -2215
CDK5 -2184
NELFE -2161
TAF12 -2056
EHMT1 -1982
NPM1 -1969
GTF2F1 -1941
CDK7 -1843
ATR -1803
POLR2C -1770
NELFB -1717
CDKN1B -1705
PCBP4 -1688
TFDP2 -1654
YWHAQ -1651
PCNA -1619
CCNA1 -1611
ING5 -1585
CNOT6 -1429
PLAGL1 -1397
TAF5 -1384
TMEM219 -1373
CNOT3 -1359
ERCC2 -1327
RPA3 -1283
LAMTOR3 -1274
TOPBP1 -1223
NUAK1 -1130
TNFRSF10A -1024
BCL2L14 -1017
MDM4 -1010
CARM1 -961
AURKA -949
TBP -894
TNFRSF10D -848
PHF20 -786
E2F1 -730
SESN2 -716
TAF15 -667
SGK1 -637
NDRG1 -621
CREBBP -600
COX18 -534
CNOT4 -498
CHD4 -474
BANP -424
RBBP8 -381
ELOC -362
PRDM1 -339
BRD7 -205
PIP4K2C -185
CSNK2A1 -74
CDC25C -70
CENPJ 58
GATAD2A 243
AKT3 336
GLS 367
PRMT1 395
BNIP3L 490
E2F4 509
SMYD2 545
RAD9A 732
CNOT10 748
RPTOR 783
PIDD1 867
PPP2R1B 892
PRKAB1 923
POLR2A 926
POLR2F 952
YWHAE 1028
TAF11 1035
RFC3 1186
MAP2K6 1198
SUPT5H 1279
GLS2 1315
DAXX 1511
MOV10 1527
POLR2L 1607
SESN1 1623
SSRP1 1699
CCNK 1834
PRKAA1 1908
RAD51D 1914
HIPK2 1935
TFDP1 2022
RBL1 2033
BIRC5 2072
RNF34 2132
TP63 2197
FANCD2 2346
AGO3 2357
E2F8 2358
COX16 2376
MDC1 2449
CYCS 2521
CCNA2 2601
YWHAG 2714
CDKN1A 2787
DNA2 2795
JMY 2804
MAPK11 2820
ATM 2903
GTF2H3 3037
RMI1 3219
CNOT2 3383
TXN 3461
BRIP1 3502
NELFA 3536
AGO1 3563
COX7C 3686
HDAC2 3695
USP7 3746
YWHAH 3766
RHNO1 3791
POLR2K 3831
PRR5 3859
CDK12 3900
MNAT1 3936
COX5A 3940
GTF2H4 4003
MSH2 4207
L3MBTL1 4223
PMS2 4308
TSC1 4362
GADD45A 4410
RFFL 4446
SETD9 4478
POLR2G 4485
TAF4B 4648
CDK1 4811
TP53BP2 4842
CNOT1 4845
GATAD2B 4901
CHEK1 4953
TAF1L 4990
ERCC3 5084
TXNRD1 5325
BID 5349
GPX2 5366
EHMT2 5380
GTF2F2 5497
FANCC 5520
MRE11 5638
CCNH 5718
TAF13 5751
KMT5A 5946
PRKAG2 5952
MTOR 5987
PPP1R13B 6097
RBBP4 6098
PRMT5 6165
COX6C 6211
TIGAR 6349
SFN 6381
RMI2 6447
TNRC6C 6460
PRDX1 6484
ZNF385A 6537
PRKAG3 6539
TRIAP1 6607
MAPKAP1 6622
DDIT4 6655
POU4F1 6677
CRADD 6684
TP73 6707
TP53 6860
TNFRSF10C 6886
CASP10 7028
COX6B1 7082
TAF7 7083
PRELID3A 7174
BTG2 7419
RAD9B 7606
CHEK2 7684
PMAIP1 7696
TNKS1BP1 7718
POLR2I 7727
TNFRSF10B 7776
PIP4P1 8123
FANCI 8332
COX5B 8356
PRKAB2 8467
UBA52 8631
BRCA1 8859
NOC2L 8965
STEAP3 8972
TAF10 9057
PPP2R1A 9244
PPP2CB 9331
CHD3 9403
ELOA2 9558
ZNF420 9758
TCEA1 10191
TP53AIP1 10220
NLRC4 10477


REACTOME_AMINO_ACID_CONJUGATION

REACTOME_AMINO_ACID_CONJUGATION
145
set REACTOME_AMINO_ACID_CONJUGATION
setSize 9
pANOVA 0.00282
s.dist 0.575
p.adjustANOVA 0.147



Top enriched genes

Top 20 genes
GeneID Gene Rank
ACSM2B 10724
ACSM2A 10379
ACSM5 10304
ACSM4 10158
GLYAT 9669
GLYATL2 9504
GLYATL1 7831
ACSM1 -4118
GLYATL3 -7966

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ACSM2B 10724
ACSM2A 10379
ACSM5 10304
ACSM4 10158
GLYAT 9669
GLYATL2 9504
GLYATL1 7831
ACSM1 -4118
GLYATL3 -7966


REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE

REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE
857
set REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE
setSize 35
pANOVA 0.00286
s.dist -0.291
p.adjustANOVA 0.147



Top enriched genes

Top 20 genes
GeneID Gene Rank
PDIA3 -11024
MOGS -10503
UBB -9922
MLEC -9627
RNF5 -9153
SYVN1 -9037
TRIM13 -8721
VCP -8460
OS9 -6624
ENGASE -6601
UGGT1 -6394
RPS27A -5865
SEL1L -4949
PRKCSH -4145
MARCHF6 -4123
RNF139 -4104
RNF103 -4047
UBC -3937
EDEM3 -3801
UBXN1 -3734

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PDIA3 -11024
MOGS -10503
UBB -9922
MLEC -9627
RNF5 -9153
SYVN1 -9037
TRIM13 -8721
VCP -8460
OS9 -6624
ENGASE -6601
UGGT1 -6394
RPS27A -5865
SEL1L -4949
PRKCSH -4145
MARCHF6 -4123
RNF139 -4104
RNF103 -4047
UBC -3937
EDEM3 -3801
UBXN1 -3734
RAD23B -3491
EDEM1 -3353
CANX -2679
MAN1B1 -2190
EDEM2 -1690
RNF185 -1576
NGLY1 -309
UGGT2 113
AMFR 2527
GANAB 2663
DERL1 4531
PSMC1 5640
CALR 6080
DERL2 6213
UBA52 8631


REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES

REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES
50
set REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES
setSize 80
pANOVA 0.00306
s.dist -0.191
p.adjustANOVA 0.148



Top enriched genes

Top 20 genes
GeneID Gene Rank
UBA7 -10332
TPR -10116
UBB -9922
PLCG1 -9896
PPM1B -9560
NUP50 -9137
EIF4E2 -9017
PIN1 -8800
OAS3 -8307
NUP42 -8147
JAK1 -7873
IRF3 -7750
NUP98 -7640
MAPK3 -7536
NUP62 -7441
ARIH1 -7136
SEH1L -7114
NUP160 -6888
EIF4E -6843
NDC1 -6638

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
UBA7 -10332
TPR -10116
UBB -9922
PLCG1 -9896
PPM1B -9560
NUP50 -9137
EIF4E2 -9017
PIN1 -8800
OAS3 -8307
NUP42 -8147
JAK1 -7873
IRF3 -7750
NUP98 -7640
MAPK3 -7536
NUP62 -7441
ARIH1 -7136
SEH1L -7114
NUP160 -6888
EIF4E -6843
NDC1 -6638
NUP205 -6549
NUP58 -6523
KPNA5 -6485
NUP37 -6122
RPS27A -5865
KPNA1 -5788
EIF2AK2 -5557
STAT1 -5422
MX1 -5271
NUP210 -5101
NUP153 -5090
UBE2L6 -5084
NUP107 -4906
KPNA4 -4881
USP18 -4780
UBC -3937
NUP43 -3319
EIF4G2 -3162
NUP35 -3128
UBE2E1 -3038
NUP214 -2260
EIF4G3 -2095
KPNB1 -2017
EIF4E3 -1838
NUP93 -1824
UBE2N -1518
EIF4A3 -1485
EIF4A2 -1297
PDE12 -746
NUP54 -626
OAS1 -85
RNASEL 448
MX2 614
NUP155 699
ABCE1 821
IFIT1 846
HERC5 1047
POM121C 1437
NEDD4 1707
KPNA2 1830
NUP188 1951
POM121 2707
KPNA3 2725
SEC13 2762
AAAS 3650
ISG15 3654
FLNB 3765
EIF4A1 3814
OASL 3979
KPNA7 4149
RANBP2 4244
TRIM25 4288
OAS2 5369
NUP85 5382
RAE1 6150
NUP133 7196
RIGI 8418
UBA52 8631
NUP88 8810
EIF4G1 9082


REACTOME_RHOG_GTPASE_CYCLE

REACTOME_RHOG_GTPASE_CYCLE
1377
set REACTOME_RHOG_GTPASE_CYCLE
setSize 71
pANOVA 0.00309
s.dist -0.203
p.adjustANOVA 0.148



Top enriched genes

Top 20 genes
GeneID Gene Rank
RHOG -10371
ARHGEF5 -10204
ARHGAP5 -10009
LAMTOR1 -9994
NDUFS3 -9845
ELMO2 -9162
CDC42EP1 -9105
HSPE1 -9060
LMAN1 -9002
TMPO -8938
VRK2 -8311
STBD1 -8245
PAK2 -7893
ITGB1 -7812
ESYT1 -7622
PGRMC2 -7565
YKT6 -7534
ANKLE2 -7446
TFRC -7152
LETM1 -6740

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RHOG -10371
ARHGEF5 -10204
ARHGAP5 -10009
LAMTOR1 -9994
NDUFS3 -9845
ELMO2 -9162
CDC42EP1 -9105
HSPE1 -9060
LMAN1 -9002
TMPO -8938
VRK2 -8311
STBD1 -8245
PAK2 -7893
ITGB1 -7812
ESYT1 -7622
PGRMC2 -7565
YKT6 -7534
ANKLE2 -7446
TFRC -7152
LETM1 -6740
PLD1 -6418
ARHGDIA -6213
ARHGAP1 -5110
GARRE1 -4998
PIK3R1 -4826
DSG2 -4486
ARHGEF26 -4444
KTN1 -4390
ARFGAP3 -3382
STX5 -3175
SHMT2 -3079
MCF2L -3071
ARHGEF16 -2681
VAPB -2667
PLEKHG3 -2583
ERBIN -2524
ARHGDIB -2366
VAMP3 -2340
MCAM -2086
ARHGAP35 -2043
ARHGAP32 -1951
DOCK3 -1836
ARHGAP39 -1250
VAV1 -1031
CDC42 -698
VAV3 -548
ITSN1 -134
IQGAP2 181
LBR 359
VANGL1 799
PREX1 918
ARHGAP21 1358
DOCK2 1482
ARHGDIG 1915
RAB7A 2025
DIAPH3 2660
DOCK5 2772
MAP3K11 2862
DOCK4 3392
CYFIP1 3590
MPP7 3776
KALRN 3815
CAV1 4085
LEMD3 4569
NDUFA5 4691
PAK4 6259
DOCK1 6661
EPHA2 7140
TRIO 7398
DEPDC1B 8821
VAV2 9364


REACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION

REACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION
1395
set REACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION
setSize 140
pANOVA 0.00325
s.dist -0.144
p.adjustANOVA 0.148



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2AC14 -10913.0
H3C12 -10835.0
H2BC14 -10763.0
CDK9 -10699.0
H4C9 -10310.0
H2AC20 -10156.0
CXXC5 -9752.0
H2BC3 -9544.0
H2BC9 -9300.5
H3C7 -9300.5
CBFB -9179.0
FKBP4 -9167.0
KAT2B -9054.0
H3C1 -8620.0
H3C3 -8519.0
H4C16 -8404.0
H2BC21 -8354.0
FOSB -8252.0
CHD1 -8166.0
HDAC1 -7942.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2AC14 -10913.0
H3C12 -10835.0
H2BC14 -10763.0
CDK9 -10699.0
H4C9 -10310.0
H2AC20 -10156.0
CXXC5 -9752.0
H2BC3 -9544.0
H2BC9 -9300.5
H3C7 -9300.5
CBFB -9179.0
FKBP4 -9167.0
KAT2B -9054.0
H3C1 -8620.0
H3C3 -8519.0
H4C16 -8404.0
H2BC21 -8354.0
FOSB -8252.0
CHD1 -8166.0
HDAC1 -7942.0
POLR2E -7862.0
KAT5 -7841.0
H4C12 -7830.0
EBAG9 -7545.0
POLR2D -7167.0
H3-3B -7000.0
AGO4 -6874.0
FOS -6648.0
ATF2 -6615.0
MYC -6612.0
KDM1A -6600.0
TLE3 -6579.0
PTGES3 -6480.0
JUND -6426.0
EP300 -6367.0
AXIN1 -6274.0
POLR2H -6221.0
H2BC15 -6116.0
RAD21 -5925.0
CCND1 -5842.0
HSP90AB1 -5719.0
ERBB4 -5713.0
H2BC26 -5544.0
RUNX1 -5488.0
TNRC6A -5305.0
MYB -5263.0
KCTD6 -4666.0
ZNF217 -4619.0
POLR2B -4576.0
H2AC18 -4497.5
H2AC19 -4497.5
H3C10 -4463.0
CXCL12 -4284.0
H3-3A -4272.0
STAG1 -4195.0
GATA3 -4127.0
H2BC12 -4085.0
SP1 -4003.0
AGO2 -3870.0
JUN -3450.0
H4C11 -3297.0
MED1 -3252.0
POU2F1 -3130.0
H2AZ2 -3002.0
H2AC6 -2934.0
TNRC6B -2859.0
GTF2A2 -2825.0
H4C1 -2748.0
CCNT1 -2694.0
POLR2J -2572.0
NCOA2 -2571.0
GPAM -2108.0
H4C13 -1989.0
H4C6 -1963.0
GTF2F1 -1941.0
FOXA1 -1881.0
NR5A2 -1793.0
POLR2C -1770.0
H4C3 -1564.0
SMC3 -1180.0
CARM1 -961.0
TBP -894.0
CREBBP -600.0
YY1 36.0
H3C11 151.0
TFF1 335.0
PRMT1 395.0
BCL2 612.0
TGFA 801.0
POLR2A 926.0
POLR2F 952.0
NRIP1 1401.0
ESR1 1465.0
MOV10 1527.0
NCOA3 1539.0
POLR2L 1607.0
KPNA2 1830.0
H4C5 2140.0
AGO3 2357.0
H2AC8 2496.0
H2AC7 2644.5
H2BC7 2644.5
KANK1 2728.0
H2AZ1 2788.0
NCOA1 2974.0
H4C2 3043.0
H2BC4 3069.0
H2BC1 3439.0
KDM4B 3497.0
PGR 3530.0
AGO1 3563.0
H2BC10 3582.0
POLR2K 3831.0
CTSD 3926.0
GTF2A1 4397.0
POLR2G 4485.0
H4C4 4495.0
DDX5 4556.0
H2BC5 4649.0
H2BC11 4747.0
H2BC13 4779.0
H4C8 5287.0
GTF2F2 5497.0
H2AX 5736.0
H3C8 5831.0
TNRC6C 6460.0
H2AJ 6509.0
USF1 6544.0
HSP90AA1 6611.0
H2BC8 7037.0
GREB1 7116.0
H2BC6 7179.0
H3C4 7300.0
H3C6 7676.0
POLR2I 7727.0
H3C2 8265.0
H2AC4 9304.0
USF2 9588.0
TFF3 9893.0
H2BC17 10609.0


REACTOME_GPCR_LIGAND_BINDING

REACTOME_GPCR_LIGAND_BINDING
834
set REACTOME_GPCR_LIGAND_BINDING
setSize 444
pANOVA 0.00344
s.dist 0.081
p.adjustANOVA 0.148



Top enriched genes

Top 20 genes
GeneID Gene Rank
WNT8A 10885
GNGT1 10866
CCL21 10823
CCL27 10790
CXCL11 10704
GHRH 10674
XCL2 10629
PROK1 10571
RXFP4 10542
PROKR1 10508
ACKR1 10497
CCL11 10464
CCL2 10462
CCL19 10453
CXCL9 10402
CXCR1 10400
ACKR4 10380
CCL22 10303
MCHR1 10299
RHO 10289

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
WNT8A 10885
GNGT1 10866
CCL21 10823
CCL27 10790
CXCL11 10704
GHRH 10674
XCL2 10629
PROK1 10571
RXFP4 10542
PROKR1 10508
ACKR1 10497
CCL11 10464
CCL2 10462
CCL19 10453
CXCL9 10402
CXCR1 10400
ACKR4 10380
CCL22 10303
MCHR1 10299
RHO 10289
CCL7 10251
TAS2R31 10243
FPR1 10222
PRLH 10198
PTGIR 10112
LPAR6 10081
GHRHR 9845
FPR2 9833
NTS 9756
GPHA2 9746
FZD4 9727
P2RY13 9651
CXCL5 9649
QRFP 9626
AVP 9523
SSTR3 9513
DRD5 9501
VIPR1 9437
TAS2R42 9426
MLNR 9417
GPR37L1 9401
HRH1 9375
CCR3 9339
PTH2 9301
OXGR1 9292
TAAR5 9283
PLPPR4 9275
KNG1 9260
TAC3 9245
CCL16 9166
FSHB 9099
NPB 9095
SCT 9030
CCR10 8995
SCTR 8937
GRM6 8886
TAS2R4 8881
GALR3 8868
CXCR5 8864
TAS2R40 8826
EDN1 8786
ACKR3 8779
WNT2B 8695
PTH 8687
OPN4 8676
PF4 8616
GPR31 8556
TBXA2R 8554
LPAR5 8539
RRH 8504
CXCL13 8459
FFAR1 8399
AGT 8394
ADRA1D 8295
WNT9B 8268
GPR18 8236
C3AR1 8200
LPAR1 8142
CCRL2 8084
CCR4 8006
TACR2 7958
GNB2 7897
PLPPR2 7885
EDNRA 7806
CCKAR 7773
TAS2R20 7683
GALR1 7653
TAS2R3 7630
C5AR2 7612
TAAR9 7574
RXFP2 7518
BDKRB1 7464
PPY 7450
CXCR2 7444
CX3CL1 7433
XCL1 7425
TAAR8 7412
CCL20 7369
GNB3 7220
GNG4 7100
CASR 7060
HRH2 7044
CX3CR1 7009
APP 6979
LTB4R 6899
PTCH2 6893
VIP 6892
GNB4 6854
RXFP1 6836
P2RY6 6762
GIP 6754
CCL5 6673
KEL 6654
HTR1F 6634
HCAR2 6564
CXCL1 6548
NTSR2 6465
MC3R 6318
CALCB 6316
HCRT 6148
HTR1D 6094
RAMP2 6087
ACKR2 6048
RAMP3 6028
WNT16 5991
CCR1 5960
FPR3 5938
C5 5885
GRM5 5878
XCR1 5759
CXCL16 5754
CHRM3 5746
KISS1 5731
ADRB2 5673
GNG11 5658
C5AR1 5619
MC2R 5615
HTR2A 5588
PRLHR 5562
GNAS 5452
AGTR1 5444
EDN2 5387
TAAR2 5386
NPSR1 5291
PROK2 5264
GABBR2 5124
HTR1B 5122
F2 5015
RGR 4945
BDKRB2 4929
PSAP 4915
HRH3 4914
SAA1 4861
TAS2R9 4860
CCL1 4827
LTB4R2 4780
HTR5A 4749
WNT7A 4730
ADRB3 4643
GAL 4640
CORT 4542
S1PR3 4538
FZD2 4533
PMCH 4483
PTH1R 4367
NPY 4165
AVPR1B 4019
DRD4 4013
INSL5 3986
GALR2 3941
GPR17 3908
CCR8 3902
WNT5A 3886
NPFFR1 3846
GCG 3800
EDN3 3792
CMKLR1 3725
OXER1 3704
PLPPR5 3629
LHB 3546
CCR5 3473
TAS1R3 3423
CCL17 3403
TAAR1 3396
HCRTR1 3380
GPR37 3308
VIPR2 3248
NTSR1 3155
CXCL6 3141
GNB1 3133
RAMP1 3132
LPAR3 3098
HTR7 3082
HTR4 2981
GNG5 2970
GABBR1 2916
CCL25 2892
PPBP 2850
TACR1 2822
HCAR1 2799
CRHR2 2774
PTGER3 2695
NMS 2506
NLN 2374
TAS2R38 2228
P2RY12 2091
KISS1R 2029
GNG7 1989
NPFFR2 1756
CD55 1754
TRHR 1729
TSHB 1626
TAS2R46 1625
PTGDR 1512
TSHR 1504
ADGRE2 1425
ADGRE1 1414
GNG12 1262
TAS2R7 1261
SUCNR1 1231
PTGER2 1100
S1PR2 1076
CCL3 1037
DRD1 1021
MTNR1B 1018
CCR7 1001
P2RY11 984
FZD6 955
HTR1E 946
TAS2R8 944
QRFPR 904
PROKR2 893
CXCR6 818
TAS2R30 766
NPS 736
UCN2 708
DRD2 659
NPBWR2 644
CHRM5 497
GRM1 450
GPR39 434
MC5R 158
TAS1R1 148
CNR1 143
OPRD1 139
WNT11 19
GPER1 -1
WNT4 -5
ADRA1B -142
GPBAR1 -285
WNT2 -310
ADCYAP1R1 -371
PENK -431
ADGRE3 -490
P2RY14 -587
PYY -684
PTGER1 -854
F2RL3 -857
GRM8 -928
GNB5 -937
ADORA2A -996
GPR68 -1045
CHRM2 -1089
C3 -1115
WNT3 -1187
GRM3 -1286
CNR2 -1324
TAS2R19 -1340
FZD10 -1356
ADM -1388
GPR55 -1390
ADRA2C -1416
ADORA1 -1522
GRM7 -1590
PNOC -1687
CALCA -1785
HTR6 -1835
MTNR1A -1952
GNRHR -1981
OPRM1 -2020
PTH2R -2045
TAS2R13 -2162
PDYN -2179
GPHB5 -2191
NPY2R -2224
CRHR1 -2254
ECE2 -2305
HEBP1 -2389
PTHLH -2404
WNT7B -2433
OPN3 -2628
TAS2R10 -2633
ADORA3 -2729
PTGFR -2870
GRP -2947
POMC -3062
GNRH2 -3065
CXCL8 -3101
SMO -3192
MC1R -3198
CCR2 -3231
TAS2R14 -3250
WNT10A -3256
CALCR -3282
PTAFR -3295
ECE1 -3496
PTCH1 -3554
GNRH1 -3608
MLN -3800
PTGER4 -3838
GNG2 -3853
CXCL2 -3874
TACR3 -3919
DHH -3928
TAS2R39 -4005
WNT1 -4015
ADORA2B -4062
NPBWR1 -4112
SST -4116
SSTR5 -4213
CXCL12 -4284
GPR132 -4365
CXCR4 -4374
WNT10B -4405
OXT -4455
CCL28 -4503
WNT3A -4647
FFAR4 -4659
TAS2R60 -4681
GNGT2 -4682
WNT9A -4718
AVPR1A -4743
HRH4 -4758
GLP2R -4772
GPR65 -4785
CCKBR -4855
UTS2B -4895
PLPPR1 -4905
NPFF -4979
GNG13 -4992
ADCYAP1 -5055
FFAR2 -5250
CCL13 -5265
GHSR -5266
TAS2R50 -5291
OPN5 -5312
MCHR2 -5387
LHCGR -5396
TAS1R2 -5499
OPRL1 -5510
SSTR2 -5603
SHH -5623
F2R -5657
UTS2R -5676
OXTR -5849
GRM2 -5859
GPR35 -6038
FZD3 -6098
CRH -6121
APLNR -6124
TAAR6 -6175
S1PR1 -6304
NMB -6377
DRD3 -6496
PTGDR2 -6562
GRM4 -6602
UTS2 -6689
SSTR4 -6776
UCN3 -6777
ADM2 -6780
FZD5 -6885
PLPPR3 -6969
GPR4 -7035
GPRC6A -7043
INSL3 -7175
WNT8B -7208
HTR2B -7249
CALCRL -7309
RXFP3 -7397
P2RY1 -7406
FFAR3 -7424
TAS2R41 -7475
GLP1R -7514
ADRA1A -7568
FSHR -7583
CHRM1 -7639
EDNRB -7684
CGA -7880
ADRB1 -7882
TAS2R5 -7976
GHRL -8027
F2RL1 -8084
CXCL10 -8093
FZD8 -8168
ADGRE5 -8238
F2RL2 -8350
CYSLTR2 -8391
OPN1SW -8419
IHH -8502
S1PR4 -8632
TAS2R16 -8633
GIPR -8694
GNG10 -8827
ADRA2A -8840
ANXA1 -8847
SSTR1 -8925
NPY1R -8972
FZD7 -9111
GPR183 -9116
NPY5R -9125
CHRM4 -9128
CCR6 -9136
S1PR5 -9138
OPRK1 -9324
UCN -9392
TRH -9444
P2RY2 -9485
CRHBP -9536
LPAR2 -9569
TAS2R1 -9591
CCK -9598
ADRA2B -9646
TAC1 -9677
NMUR1 -9759
CCL23 -9803
IAPP -9844
WNT6 -9885
HTR1A -9929
GNG8 -9993
NMUR2 -9996
NPW -10020
NMU -10034
HCRTR2 -10051
GNG3 -10058
TAS2R43 -10086
CXCL3 -10102
MC4R -10228
NMBR -10257
FZD9 -10487
RLN3 -10491
CCR9 -10511
FZD1 -10579
RLN2 -10740
CCL4 -11032


REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION

REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION
367
set REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION
setSize 59
pANOVA 0.00354
s.dist -0.22
p.adjustANOVA 0.148



Top enriched genes

Top 20 genes
GeneID Gene Rank
ARC -10482
SRF -10256
DUSP7 -9909
CDK5R1 -9822
FOSB -8252
ASCL1 -8241
TRIB1 -7816
MAPKAPK2 -7786
MAPK3 -7536
RPS6KA5 -7113
ID3 -6813
TPH1 -6659
FOS -6648
PPP2CA -6627
ATF2 -6615
JUNB -6577
JUND -6426
EP300 -6367
NAB2 -6323
LYL1 -5411

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ARC -10482
SRF -10256
DUSP7 -9909
CDK5R1 -9822
FOSB -8252
ASCL1 -8241
TRIB1 -7816
MAPKAPK2 -7786
MAPK3 -7536
RPS6KA5 -7113
ID3 -6813
TPH1 -6659
FOS -6648
PPP2CA -6627
ATF2 -6615
JUNB -6577
JUND -6426
EP300 -6367
NAB2 -6323
LYL1 -5411
EGR3 -5056
MAPK14 -4997
RRAD -4986
DUSP3 -4516
F3 -4507
DNM2 -4245
MEF2A -3731
PPP2R5D -3640
MEF2D -3575
EGR4 -2970
RPS6KA1 -2943
NAB1 -2431
TCF12 -2412
EGR2 -2402
CDK5 -2184
MAPK1 -1262
ATF1 -1084
SGK1 -637
ID1 -535
CHD4 -474
EGR1 232
DUSP6 387
ID4 595
RPS6KA2 661
CDK5R2 884
PPP2R1B 892
FOSL1 1898
ID2 1912
MEF2C 1924
SH3GL3 2522
CREB1 2805
MAPK11 2820
DUSP4 3211
VGF 4029
REST 6265
VRK3 7130
MAPK7 8612
PPP2R1A 9244
PPP2CB 9331


REACTOME_PHOSPHOLIPID_METABOLISM

REACTOME_PHOSPHOLIPID_METABOLISM
136
set REACTOME_PHOSPHOLIPID_METABOLISM
setSize 201
pANOVA 0.00357
s.dist -0.119
p.adjustANOVA 0.148



Top enriched genes

Top 20 genes
GeneID Gene Rank
PLA2G1B -10863
GDPD3 -10502
ALPI -10500
PHOSPHO1 -10112
DGAT1 -10026
TNFAIP8L2 -9915
INPPL1 -9908
CDS1 -9744
LIPI -9715
PIP5K1A -9642
PISD -9534
BCHE -9512
PCYT1A -9242
LPCAT4 -9188
GDE1 -9032
MTMR10 -8979
PLA2G3 -8675
MIGA2 -8672
CHKB -8520
PLAAT2 -8497

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PLA2G1B -10863
GDPD3 -10502
ALPI -10500
PHOSPHO1 -10112
DGAT1 -10026
TNFAIP8L2 -9915
INPPL1 -9908
CDS1 -9744
LIPI -9715
PIP5K1A -9642
PISD -9534
BCHE -9512
PCYT1A -9242
LPCAT4 -9188
GDE1 -9032
MTMR10 -8979
PLA2G3 -8675
MIGA2 -8672
CHKB -8520
PLAAT2 -8497
ARF1 -8415
ACHE -8403
PLA2G15 -8290
PLEKHA4 -8288
OSBPL5 -8283
DDHD1 -8205
ARF3 -8191
SLC44A2 -8106
GPAT4 -8049
PLD3 -8021
PLEKHA1 -7803
GPCPD1 -7588
PNPLA8 -7363
CDIPT -7325
PITPNM1 -7274
RAB4A -7183
PIKFYVE -6977
LPIN2 -6975
CSNK2A2 -6773
PTPMT1 -6767
AGK -6532
AGPAT2 -6514
PLD1 -6418
SACM1L -6240
PLEKHA8 -6086
LPCAT2 -5918
PLA2G5 -5823
PLEKHA5 -5818
PLAAT5 -5805
MTMR6 -5794
ETNPPL -5761
PIP4K2B -5303
CSNK2B -5093
PGS1 -4933
PLA2G4A -4850
TNFAIP8 -4848
DGAT2 -4831
PIK3R1 -4826
CHPT1 -4761
CHKA -4749
LPCAT1 -4674
CPNE1 -4665
PIK3CD -4566
TNFAIP8L1 -4532
CEPT1 -4492
PIK3CA -4471
GPAT2 -4458
MTMR12 -4383
DDHD2 -4306
MTMR7 -4217
GPD2 -4171
PCYT2 -4068
PTEN -3951
PIK3R5 -3852
MBOAT2 -3839
MTMR9 -3737
PIP4K2A -3648
AGPAT1 -3586
LPCAT3 -3370
PIK3R2 -3341
PLA2G10 -3223
CHAT -3193
PIK3CG -3094
PLA1A -3069
SLC44A3 -3064
GDPD1 -3006
PTDSS2 -2979
INPP4A -2969
PIK3C3 -2844
INPP4B -2806
PLA2R1 -2719
HADHB -2566
STARD10 -2556
PNPLA6 -2539
PLBD1 -2532
OSBPL8 -2426
PLD2 -2384
MGLL -2194
GDPD5 -2155
GPAM -2108
RAB5A -2060
PIK3C2G -2006
MTMR3 -1841
INPP5E -1801
PLAAT4 -1707
PNPLA3 -1676
PLA2G2A -1472
PIK3C2A -1352
VAC14 -1306
LPIN1 -1288
PLA2G4F -1209
PIK3R4 -1175
LPGAT1 -1058
PLEKHA2 -920
PLA2G4C -886
SBF2 -726
MTMR14 -659
PTDSS1 -554
PIK3R3 -472
MBOAT1 -453
CRLS1 -400
PI4KB -280
AGPAT3 -262
PITPNM3 -218
MTMR4 -204
PIP4K2C -185
PNPLA7 -107
CSNK2A1 -74
ACP6 -73
LCLAT1 26
MTMR2 140
SLC44A5 211
STARD7 216
PNPLA2 397
ETNK1 466
GPD1 731
PITPNM2 777
PITPNB 857
PIK3CB 1073
PTPN13 1353
GPD1L 1361
SBF1 1479
PLAAT3 1571
PLAAT1 1825
PLA2G12A 2303
INPP5K 2387
PI4K2B 2730
CPNE3 3249
LPIN3 3343
AGPAT4 3344
PLEKHA3 3406
PIK3R6 3456
TNFAIP8L3 3508
PLA2G2E 3632
MBOAT7 3651
PLD6 3756
SYNJ2 4265
PI4KA 4276
SELENOI 4467
PLA2G4B 4540
PLD4 4582
PIP5K1B 4641
RAB14 4706
HADHA 4782
SYNJ1 5025
GNPAT 5043
MIGA1 5198
SLC44A4 5213
OSBPL10 5367
PLA2G4E 5368
CDS2 5374
INPP5D 5405
PEMT 5414
INPP5F 5551
SLC44A1 5644
PLA2G6 5800
AGPAT5 5957
FIG4 5994
PIP5K1C 6284
PLEKHA6 6492
PLA2G4D 6496
ABHD4 6579
PCTP 7029
CPNE7 7287
PIK3C2B 7350
CPNE6 7494
RUFY1 7543
TMEM86B 7614
PI4K2A 7700
ENPP6 8108
PIP4P1 8123
MFSD2A 8127
LIPH 8151
ABHD3 8256
TPTE 8722
PLA2G2F 8862
PLB1 9070
ETNK2 9368
PLA2G2D 9689
TPTE2 9693
INPP5J 10535


REACTOME_TNF_SIGNALING

REACTOME_TNF_SIGNALING
1192
set REACTOME_TNF_SIGNALING
setSize 54
pANOVA 0.0036
s.dist -0.229
p.adjustANOVA 0.148



Top enriched genes

Top 20 genes
GeneID Gene Rank
USP21 -10504
UBE2D2 -9963
RBCK1 -9943
UBB -9922
SPPL2B -9883
OTUD1 -9854
MAP3K7 -9289
CLIP3 -9166
STUB1 -9156
MIB2 -8889
BIRC2 -8215
SMPD2 -8103
ULK1 -7965
MAPKAPK2 -7786
CYLD -6369
RPS27A -5865
TNFAIP3 -5601
UBE2D3 -5052
TAX1BP1 -4683
IKBKB -4657

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
USP21 -10504
UBE2D2 -9963
RBCK1 -9943
UBB -9922
SPPL2B -9883
OTUD1 -9854
MAP3K7 -9289
CLIP3 -9166
STUB1 -9156
MIB2 -8889
BIRC2 -8215
SMPD2 -8103
ULK1 -7965
MAPKAPK2 -7786
CYLD -6369
RPS27A -5865
TNFAIP3 -5601
UBE2D3 -5052
TAX1BP1 -4683
IKBKB -4657
CHUK -4148
SPATA2 -3978
UBC -3937
SPPL2A -3758
BAG4 -3755
CASP8 -3233
FADD -3142
RIPK1 -3070
NSMAF -2725
USP2 -2718
TRAF2 -2645
SHARPIN -1817
MADD -1216
TRAF1 -862
RACK1 -147
TRADD -38
TBK1 -8
TAB1 598
TAB2 685
CFLAR 745
OTUD7B 940
BIRC3 1698
ADAM17 1716
SMPD3 2126
OPTN 2383
USP4 2593
UBE2L3 3798
RNF31 4289
OTULIN 5576
TNF 6076
UBE2D1 6123
TNFRSF1A 7280
IKBKE 8536
UBA52 8631


REACTOME_DEUBIQUITINATION

REACTOME_DEUBIQUITINATION
1000
set REACTOME_DEUBIQUITINATION
setSize 260
pANOVA 0.00367
s.dist -0.105
p.adjustANOVA 0.148



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2AC14 -10913.0
PSMB11 -10777.0
H2BC14 -10763.0
TADA2B -10616.0
USP21 -10504.0
AXIN2 -10479.0
RNF123 -10351.0
INO80D -10346.0
KEAP1 -10320.0
H2AC20 -10156.0
SMURF2 -10094.0
VDAC1 -9974.0
UBB -9922.0
TGFB1 -9661.0
H2BC3 -9544.0
SEM1 -9467.0
RHOT1 -9347.0
H2BC9 -9300.5
MAP3K7 -9289.0
CLSPN -9258.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2AC14 -10913.0
PSMB11 -10777.0
H2BC14 -10763.0
TADA2B -10616.0
USP21 -10504.0
AXIN2 -10479.0
RNF123 -10351.0
INO80D -10346.0
KEAP1 -10320.0
H2AC20 -10156.0
SMURF2 -10094.0
VDAC1 -9974.0
UBB -9922.0
TGFB1 -9661.0
H2BC3 -9544.0
SEM1 -9467.0
RHOT1 -9347.0
H2BC9 -9300.5
MAP3K7 -9289.0
CLSPN -9258.0
KAT2B -9054.0
VDAC3 -8997.0
PSMD14 -8863.0
ACTB -8733.0
SMAD7 -8676.0
RNF146 -8661.0
MYSM1 -8656.0
TADA3 -8645.0
VCPIP1 -8629.0
TOMM20 -8465.0
H2AC15 -8462.0
VCP -8460.0
H2BC21 -8354.0
ABRAXAS1 -8254.0
BIRC2 -8215.0
MDM2 -8204.0
USP47 -8157.0
SIAH2 -7934.0
JOSD2 -7883.0
DDB2 -7840.0
USP33 -7710.0
NOD1 -7572.0
TNIP2 -7469.0
SUDS3 -7460.0
H2AC16 -7367.0
USP42 -7230.0
RCE1 -7189.0
USP14 -7091.0
USP19 -7051.0
PSMD9 -6945.0
APC -6781.0
SMAD2 -6738.0
USP20 -6618.0
MYC -6612.0
TRIM4 -6535.0
PSMB8 -6491.0
CYLD -6369.0
EP300 -6367.0
ASXL1 -6340.0
AXIN1 -6274.0
KAT2A -6227.0
CCP110 -6165.0
STAM2 -6140.0
H2BC15 -6116.0
PSMA8 -6030.0
TGFBR2 -6018.0
ACTL6A -6003.0
RNF135 -5931.0
RPS27A -5865.0
PSMD13 -5830.0
TNKS -5802.0
PSME4 -5742.0
JOSD1 -5735.0
TNFAIP3 -5601.0
H2BC26 -5544.0
PSMD11 -5394.0
BECN1 -5275.0
PSMB3 -5218.0
STAMBP -5181.0
RIPK2 -4991.0
H2AC25 -4934.0
ADRM1 -4877.0
USP18 -4780.0
TFPT -4752.0
BARD1 -4531.0
RUVBL1 -4506.0
H2AC18 -4497.5
H2AC19 -4497.5
MBD5 -4461.0
ACTR8 -4379.0
PSMB5 -4259.0
ATXN7 -4219.0
GATA3 -4127.0
IDE -4110.0
H2BC12 -4085.0
PSME2 -4065.0
PSMD2 -3966.0
PTEN -3951.0
UBC -3937.0
STAM -3922.0
USP25 -3793.0
HGS -3601.0
OTUD7A -3535.0
PSMB4 -3508.0
RAD23B -3491.0
TNIP3 -3486.0
OTUB1 -3463.0
KDM1B -3373.0
NFRKB -3352.0
FKBP8 -3196.0
IFIH1 -3173.0
USP24 -3132.0
RIPK1 -3070.0
PSMD5 -2953.0
H2AC6 -2934.0
ARRB2 -2917.0
TNIP1 -2832.0
PSMB7 -2811.0
USP34 -2771.0
PSMC5 -2753.0
USP2 -2718.0
TRAF2 -2645.0
ABRAXAS2 -2641.0
USP13 -2602.0
MAT2B -2520.0
PSMD3 -2367.0
UFD1 -2223.0
BAP1 -2015.0
HIF1A -1895.0
PSMD6 -1831.0
CCNA1 -1611.0
BABAM1 -1536.0
MCRS1 -1432.0
PSMD7 -1362.0
H2AC1 -1303.0
FOXK1 -1049.0
MDM4 -1010.0
CFTR -693.0
USP48 -673.0
NEDD8 -559.0
CDC25A -466.0
USP22 -284.0
PSMA1 -272.0
MBD6 -250.0
USP16 -144.0
UCHL1 -102.0
PSME1 -45.0
OTUB2 -3.0
USP37 32.0
YY1 36.0
ASXL2 62.0
PSMC2 97.0
PSMD1 215.0
STAMBPL1 309.0
RAD23A 349.0
SMAD1 410.0
TAB1 598.0
PSMB6 781.0
OTUD7B 940.0
NFKBIA 1005.0
POLB 1048.0
ACTR5 1167.0
ESR1 1465.0
PSMA7 1653.0
BIRC3 1698.0
INO80C 1736.0
PSMA3 1747.0
INO80B 1812.0
IL33 1873.0
PSMA2 1886.0
PRKN 1954.0
USP15 2016.0
CDC20 2128.0
TRAF6 2148.0
TRAF3 2206.0
TOMM70 2355.0
H2AC8 2496.0
USP4 2593.0
CCNA2 2601.0
NOD2 2618.0
H2AC7 2644.5
H2BC7 2644.5
INO80E 2823.0
PSMB9 2951.0
H2AC21 3029.0
H2BC4 3069.0
TGFBR1 3076.0
USP28 3139.0
USP30 3282.0
H2BC1 3439.0
SMAD3 3457.0
PSMA6 3500.0
UCHL3 3504.0
PTRH2 3524.0
H2BC10 3582.0
SMAD4 3622.0
USP7 3746.0
PSMC6 3773.0
USP10 3782.0
H2AC13 4182.0
RHOA 4216.0
UIMC1 4260.0
TRIM25 4288.0
USP12 4295.0
BABAM2 4327.0
PSME3 4494.0
SENP8 4543.0
ATXN3 4557.0
PSMC3 4583.0
FOXK2 4644.0
H2BC5 4649.0
H2BC11 4747.0
INO80 4751.0
H2BC13 4779.0
USP3 4788.0
CDK1 4811.0
PSMB2 4923.0
TNKS2 5009.0
ZRANB1 5156.0
WDR48 5225.0
USP44 5246.0
PSMB1 5472.0
TRRAP 5543.0
PSMC1 5640.0
ADRB2 5673.0
USP8 5722.0
PSMD8 5747.0
SKP2 5770.0
YOD1 5841.0
VDAC2 6034.0
UBE2D1 6123.0
USP49 6242.0
PSMB10 6504.0
USP5 6594.0
TP53 6860.0
MAVS 6952.0
H2BC8 7037.0
PSMA4 7118.0
PSMD4 7146.0
H2BC6 7179.0
PSMC4 7533.0
MUL1 7622.0
ARRB1 7821.0
OTUD3 7884.0
UCHL5 8055.0
NLRP3 8147.0
H2AC11 8172.0
PSMA5 8306.0
RIGI 8418.0
PSMF1 8543.0
UBA52 8631.0
SNX3 8718.0
WDR20 8855.0
BRCA1 8859.0
TAF10 9057.0
H2AC4 9304.0
PSMD12 9475.0
H2AC12 9576.0
H2AC17 10569.0
H2BC17 10609.0


REACTOME_DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_COMPLEX

REACTOME_DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_COMPLEX
606
set REACTOME_DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_COMPLEX
setSize 39
pANOVA 0.00369
s.dist -0.269
p.adjustANOVA 0.148



Top enriched genes

Top 20 genes
GeneID Gene Rank
PYGO2 -10460
TLE1 -10160
UBB -9922
SOX9 -9872
KMT2D -9460
BCL9 -9339
XPO1 -8068
HDAC1 -7942
YWHAZ -7837
TLE4 -7428
PYGO1 -7138
APC -6781
TLE3 -6579
ASH2L -6287
SOX4 -5986
RPS27A -5865
TCF7 -5615
AKT1 -5462
SOX7 -5059
LEF1 -4225

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PYGO2 -10460
TLE1 -10160
UBB -9922
SOX9 -9872
KMT2D -9460
BCL9 -9339
XPO1 -8068
HDAC1 -7942
YWHAZ -7837
TLE4 -7428
PYGO1 -7138
APC -6781
TLE3 -6579
ASH2L -6287
SOX4 -5986
RPS27A -5865
TCF7 -5615
AKT1 -5462
SOX7 -5059
LEF1 -4225
AKT2 -4008
UBC -3937
CTBP1 -3732
SOX2 -3095
SOX13 -2488
SOX17 -1325
BTRC -91
CTNNB1 114
CHD8 427
TCF7L2 2280
MEN1 2615
TCF7L1 2801
CTNNBIP1 2876
TLE2 3879
RBBP5 4358
SOX6 6472
CBY1 7668
UBA52 8631
BCL9L 9115


REACTOME_CELL_CYCLE_MITOTIC

REACTOME_CELL_CYCLE_MITOTIC
1112
set REACTOME_CELL_CYCLE_MITOTIC
setSize 539
pANOVA 0.00435
s.dist -0.0718
p.adjustANOVA 0.167



Top enriched genes

Top 20 genes
GeneID Gene Rank
TUBA3D -10927
H2AC14 -10913
H3C12 -10835
PSMB11 -10777
H2BC14 -10763
CCNE1 -10562
SSNA1 -10517
NCAPH2 -10390
H4C9 -10310
H2AC20 -10156
GINS4 -10139
CDKN1C -10127
TPR -10116
PTK6 -10083
UBE2S -9950
DYRK1A -9938
UBB -9922
CCNE2 -9892
TUBB4A -9800
SGO2 -9793

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TUBA3D -10927.0
H2AC14 -10913.0
H3C12 -10835.0
PSMB11 -10777.0
H2BC14 -10763.0
CCNE1 -10562.0
SSNA1 -10517.0
NCAPH2 -10390.0
H4C9 -10310.0
H2AC20 -10156.0
GINS4 -10139.0
CDKN1C -10127.0
TPR -10116.0
PTK6 -10083.0
UBE2S -9950.0
DYRK1A -9938.0
UBB -9922.0
CCNE2 -9892.0
TUBB4A -9800.0
SGO2 -9793.0
CDK11A -9600.0
H2BC3 -9544.0
CEP41 -9506.0
GOLGA2 -9498.0
TK1 -9492.0
SEM1 -9467.0
FZR1 -9437.0
H2BC9 -9300.5
H3C7 -9300.5
KIF2A -9218.0
TUBB1 -9184.0
NUP50 -9137.0
CDCA5 -9106.0
FEN1 -9104.0
HAUS2 -8968.0
TMPO -8938.0
CEP135 -8921.0
ANAPC2 -8906.0
PSMD14 -8863.0
FBXL18 -8644.0
RCC2 -8640.0
H3C1 -8620.0
H3C3 -8519.0
RAN -8481.0
H4C16 -8404.0
H2BC21 -8354.0
VRK2 -8311.0
JAK2 -8304.0
NUP42 -8147.0
PRKACA -8098.0
XPO1 -8068.0
NCAPH -8050.0
HDAC1 -7942.0
GINS1 -7932.0
CDKN2C -7847.0
H4C12 -7830.0
RPA2 -7819.0
FBXO5 -7788.0
LIG1 -7782.0
FBXL7 -7722.0
TUBAL3 -7714.0
NUP98 -7640.0
LEMD2 -7634.0
AURKB -7569.0
MAPK3 -7536.0
RBL2 -7486.0
ANKLE2 -7446.0
NUP62 -7441.0
POLD2 -7431.0
SPC24 -7280.0
CEP78 -7221.0
SKA1 -7211.0
E2F5 -7173.0
PHLDA1 -7130.0
SEH1L -7114.0
CEP76 -7103.0
TUBB2B -7059.0
TUBB -7034.0
H3-3B -7000.0
CHMP4C -6983.0
LPIN2 -6975.0
TUBGCP4 -6949.0
PSMD9 -6945.0
UBE2I -6911.0
WEE1 -6910.0
NUP160 -6888.0
CDK6 -6846.0
CSNK2A2 -6773.0
CDC16 -6705.0
CHMP2B -6673.0
CENPT -6649.0
NDC1 -6638.0
PPP2CA -6627.0
RPA1 -6619.0
MYC -6612.0
CSNK1D -6584.0
NUP205 -6549.0
RAB1B -6536.0
NUP58 -6523.0
MYBL2 -6513.0
PSMB8 -6491.0
MCM8 -6466.0
USO1 -6412.0
EP300 -6367.0
TUBB2A -6285.0
PPP1R12B -6261.0
CEP43 -6198.0
POLD3 -6193.0
BLZF1 -6189.0
CCP110 -6165.0
PPP2R5C -6138.0
NUP37 -6122.0
H2BC15 -6116.0
PSMA8 -6030.0
NINL -6010.0
DHFR -5996.0
PKMYT1 -5970.0
RAD21 -5925.0
CNTRL -5921.0
RPS27A -5865.0
TAOK1 -5863.0
ANAPC7 -5847.0
NME7 -5846.0
CCND1 -5842.0
PSMD13 -5830.0
TUBGCP5 -5811.0
CHMP3 -5755.0
PSME4 -5742.0
HSP90AB1 -5719.0
ODF2 -5700.0
RBX1 -5685.0
LIN9 -5563.0
CENPA -5551.0
H2BC26 -5544.0
DCTN3 -5539.0
RFC2 -5485.0
AKT1 -5462.0
CEP131 -5437.0
PSMD11 -5394.0
DBF4 -5393.0
TUBGCP2 -5377.0
INCENP -5364.0
CDC23 -5346.0
TUBA1B -5322.0
MCM2 -5310.0
DSN1 -5253.0
PSMB3 -5218.0
AKAP9 -5154.0
NUP210 -5101.0
SMC2 -5096.0
CSNK2B -5093.0
NUP153 -5090.0
RANGAP1 -5063.0
POLD4 -4925.0
NUP107 -4906.0
PCNT -4821.0
NUDC -4747.0
CHMP7 -4660.0
CDKN2A -4653.0
DYNC1I1 -4614.0
CDK11B -4509.0
H2AC18 -4497.5
H2AC19 -4497.5
H3C10 -4463.0
BANF1 -4441.0
DYNC1LI1 -4424.0
LYN -4414.0
NUMA1 -4370.0
CEP57 -4366.0
PPP1R12A -4325.0
CHMP4A -4321.0
CDC6 -4319.0
H3-3A -4272.0
PSMB5 -4259.0
STAG1 -4195.0
MCM10 -4157.0
H2BC12 -4085.0
PSME2 -4065.0
GORASP2 -4048.0
AKT2 -4008.0
PSMD2 -3966.0
UBC -3937.0
CDC14A -3924.0
CENPH -3918.0
RCC1 -3906.0
RAB1A -3897.0
CEP152 -3875.0
MZT2B -3844.0
CENPF -3831.0
TUBA8 -3728.0
NIPBL -3675.0
TUBB4B -3663.0
PPP2R5D -3640.0
CC2D1B -3629.0
ORC3 -3549.0
CCNB1 -3520.0
TUBG2 -3519.0
PSMB4 -3508.0
ANAPC5 -3480.0
TUBGCP6 -3436.0
DYNLL1 -3346.0
NUP43 -3319.0
H4C11 -3297.0
TPX2 -3261.0
NUP35 -3128.0
POLE2 -3083.0
UBE2E1 -3038.0
H2AZ2 -3002.0
PSMD5 -2953.0
VPS4A -2952.0
H2AC6 -2934.0
E2F3 -2925.0
RFC5 -2867.0
MZT2A -2863.0
NEK2 -2857.0
PSMB7 -2811.0
RFC4 -2759.0
PSMC5 -2753.0
H4C1 -2748.0
CDK2 -2703.0
E2F6 -2685.0
GTSE1 -2655.0
TNPO1 -2617.0
DCTN2 -2604.0
PCM1 -2569.0
SPC25 -2567.0
DYNC1I2 -2526.0
PSMD3 -2367.0
CTDNEP1 -2303.0
CCND3 -2300.0
NUP214 -2260.0
LIN54 -2233.0
IST1 -2030.0
KPNB1 -2017.0
CCND2 -2011.0
H4C13 -1989.0
ENSA -1987.0
H4C6 -1963.0
LIN52 -1953.0
CLASP2 -1938.0
MCPH1 -1917.0
CLASP1 -1913.0
PRKCB -1884.0
CDK7 -1843.0
PSMD6 -1831.0
NUP93 -1824.0
CDKN1B -1705.0
AHCTF1 -1702.0
TFDP2 -1654.0
PCNA -1619.0
CCNA1 -1611.0
BUB1 -1581.0
PPP1CB -1575.0
CHMP4B -1574.0
H4C3 -1564.0
ESCO2 -1533.0
ANAPC1 -1451.0
PSMD7 -1362.0
LPIN1 -1288.0
RPA3 -1283.0
MAPK1 -1262.0
ANAPC16 -1202.0
SMC3 -1180.0
CEP290 -1104.0
FBXW11 -1101.0
CHMP6 -1065.0
ACTR1A -1043.0
CKAP5 -979.0
GORASP1 -965.0
AURKA -949.0
PPP2R2D -932.0
SFI1 -917.0
CDC26 -850.0
WAPL -825.0
CEP250 -763.0
MAD1L1 -757.0
E2F1 -730.0
POLE3 -683.0
NUP54 -626.0
GSK3B -613.0
VRK1 -550.0
DYNLL2 -501.0
CDC25A -466.0
TUBA1C -435.0
TUBB3 -380.0
CDC25B -333.0
SDCCAG8 -294.0
BUB1B -292.0
MCM7 -290.0
TUBGCP3 -283.0
PSMA1 -272.0
NCAPG2 -253.0
TUBA3C -228.0
HAUS1 -207.0
CLIP1 -182.0
NEDD1 -174.0
HAUS6 -110.0
BTRC -91.0
CSNK2A1 -74.0
CDC25C -70.0
PSME1 -45.0
TUBA1A 53.0
CENPJ 58.0
RAB2A 60.0
SGO1 86.0
PSMC2 97.0
H3C11 151.0
PSMD1 215.0
ANAPC11 264.0
AKT3 336.0
CENPN 353.0
LBR 359.0
E2F2 403.0
MAU2 420.0
ZWILCH 472.0
E2F4 509.0
PPP1CC 566.0
NEK7 616.0
NUP155 699.0
CENPM 715.0
PSMB6 781.0
RRM2 824.0
PPP2R1B 892.0
SIRT2 930.0
NSL1 947.0
DYNC1H1 1000.0
NCAPD2 1011.0
KNL1 1022.0
YWHAE 1028.0
SUMO1 1175.0
RFC3 1186.0
CABLES1 1205.0
CENPL 1374.0
NDC80 1388.0
CEP72 1395.0
POM121C 1437.0
PSMA7 1653.0
CENPQ 1741.0
PSMA3 1747.0
CEP63 1779.0
CENPP 1810.0
PRKAR2B 1811.0
ORC1 1824.0
MAX 1879.0
PSMA2 1886.0
ORC4 1925.0
NUP188 1951.0
CENPK 1978.0
ABL1 1983.0
TFDP1 2022.0
RBL1 2033.0
MAPRE1 2039.0
RAB8A 2046.0
CENPS 2065.0
BIRC5 2072.0
SPAST 2121.0
CDC20 2128.0
H4C5 2140.0
POLE4 2141.0
SMC4 2172.0
ANAPC4 2282.0
PDS5B 2289.0
LCMT1 2291.0
CDCA8 2329.0
B9D2 2345.0
MCM6 2370.0
OPTN 2383.0
PPME1 2392.0
CDK4 2457.0
H2AC8 2496.0
MAD2L1 2515.0
PPP2R5A 2560.0
CCNA2 2601.0
H2AC7 2644.5
H2BC7 2644.5
POM121 2707.0
YWHAG 2714.0
SEC13 2762.0
ANAPC10 2777.0
CDKN1A 2787.0
H2AZ1 2788.0
DNA2 2795.0
PPP2R5E 2813.0
KIF23 2829.0
TOP2A 2834.0
PSMB9 2951.0
H4C2 3043.0
H2BC4 3069.0
ZW10 3188.0
HAUS3 3255.0
ORC6 3334.0
MCM3 3342.0
LPIN3 3343.0
DYNC1LI2 3368.0
ALMS1 3384.0
H2BC1 3439.0
CKS1B 3484.0
PSMA6 3500.0
CDK5RAP2 3539.0
H2BC10 3582.0
NEK9 3600.0
AAAS 3650.0
SKA2 3687.0
TUBA4B 3701.0
NDE1 3710.0
RFC1 3734.0
CENPC 3736.0
FKBPL 3737.0
CEP70 3767.0
PSMC6 3773.0
KIF2C 3785.0
ANAPC15 3810.0
ZWINT 3836.0
MNAT1 3936.0
CDT1 4056.0
NCAPD3 4059.0
CDC45 4138.0
NDEL1 4198.0
RANBP2 4244.0
NUF2 4302.0
MASTL 4330.0
CNEP1R1 4355.0
PLK4 4371.0
KNTC1 4417.0
POLA2 4462.0
PSME3 4494.0
H4C4 4495.0
LIN37 4508.0
TUBA3E 4513.0
LEMD3 4569.0
PSMC3 4583.0
BORA 4596.0
PPP2R5B 4645.0
H2BC5 4649.0
LMNB1 4711.0
CEP192 4728.0
H2BC11 4747.0
H2BC13 4779.0
CCNB2 4805.0
CENPU 4806.0
CDK1 4811.0
ITGB3BP 4824.0
PSMB2 4923.0
MZT1 5038.0
POLD1 5096.0
MCM4 5131.0
HAUS4 5190.0
H4C8 5287.0
GMNN 5339.0
RPS27 5348.0
FOXM1 5360.0
TUBA4A 5381.0
NUP85 5382.0
EML4 5431.0
ORC2 5457.0
PSMB1 5472.0
ESCO1 5537.0
CUL1 5560.0
PSMC1 5640.0
TYMS 5655.0
CDKN2B 5662.0
CCNH 5718.0
H2AX 5736.0
CENPO 5740.0
CHMP2A 5744.0
PSMD8 5747.0
SKP2 5770.0
H3C8 5831.0
KMT5A 5946.0
PPP2R2A 5961.0
MIS12 6046.0
PRKCA 6082.0
RBBP4 6098.0
UBE2D1 6123.0
RAE1 6150.0
SPDL1 6152.0
UBE2C 6168.0
POLE 6176.0
GINS2 6223.0
CDC7 6279.0
SET 6333.0
NCAPG 6427.0
PSMB10 6504.0
H2AJ 6509.0
MCM5 6517.0
HSP90AA1 6611.0
ARPP19 6631.0
TUBB6 6645.0
CDKN2D 6758.0
TP53 6860.0
KIF18A 6904.0
KIF20A 6920.0
PDS5A 6997.0
SRC 7032.0
H2BC8 7037.0
PSMA4 7118.0
ORC5 7143.0
PSMD4 7146.0
H2BC6 7179.0
CSNK1E 7191.0
NUP133 7196.0
H3C4 7300.0
CENPE 7426.0
BUB3 7501.0
PTTG1 7506.0
PSMC4 7533.0
HAUS5 7663.0
H3C6 7676.0
RB1 7828.0
SKP1 8064.0
HMMR 8173.0
H3C2 8265.0
CDC27 8270.0
LMNA 8304.0
PSMA5 8306.0
PRIM1 8361.0
PLK1 8371.0
PAFAH1B1 8491.0
PSMF1 8543.0
KIF2B 8586.0
UBA52 8631.0
CEP164 8705.0
TUBG1 8712.0
HAUS8 8769.0
NUP88 8810.0
DCTN1 8905.0
AJUBA 8907.0
ESPL1 8987.0
PPP2R1A 9244.0
PMF1 9251.0
H3-4 9296.0
H2AC4 9304.0
PPP2CB 9331.0
PRIM2 9451.0
PSMD12 9475.0
GINS3 9780.0
NEK6 9961.0
H2BC17 10609.0
TUBB8 10897.0


REACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES

REACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES
1633
set REACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES
setSize 7
pANOVA 0.00449
s.dist -0.62
p.adjustANOVA 0.167



Top enriched genes

Top 20 genes
GeneID Gene Rank
PGD -8953
NFE2L2 -8950
TKT -8896
MAFG -7773
TALDO1 -6537
EP300 -6367
CREBBP -600

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PGD -8953
NFE2L2 -8950
TKT -8896
MAFG -7773
TALDO1 -6537
EP300 -6367
CREBBP -600


REACTOME_CREB3_FACTORS_ACTIVATE_GENES

REACTOME_CREB3_FACTORS_ACTIVATE_GENES
1259
set REACTOME_CREB3_FACTORS_ACTIVATE_GENES
setSize 8
pANOVA 0.00451
s.dist 0.58
p.adjustANOVA 0.167



Top enriched genes

Top 20 genes
GeneID Gene Rank
DCSTAMP 9338
MBTPS1 8675
CREB3L2 8272
CREB3L1 6726
CREB3 6482
CREB3L3 5852
CREB3L4 5469
CREBRF -173

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DCSTAMP 9338
MBTPS1 8675
CREB3L2 8272
CREB3L1 6726
CREB3 6482
CREB3L3 5852
CREB3L4 5469
CREBRF -173


REACTOME_DAP12_SIGNALING

REACTOME_DAP12_SIGNALING
485
set REACTOME_DAP12_SIGNALING
setSize 27
pANOVA 0.00458
s.dist -0.315
p.adjustANOVA 0.167



Top enriched genes

Top 20 genes
GeneID Gene Rank
NRAS -10476
TYROBP -10382
PLCG1 -9896
KLRD1 -9876
GRAP2 -9541
SYK -8792
KLRK1 -8587
KRAS -7961
B2M -7892
HLA-E -7859
HRAS -7726
LCP2 -6842
RAC1 -6469
PLCG2 -6119
GRB2 -5215
PIK3R1 -4826
PIK3CA -4471
PIK3R2 -3341
FYN -804
VAV3 -548

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NRAS -10476
TYROBP -10382
PLCG1 -9896
KLRD1 -9876
GRAP2 -9541
SYK -8792
KLRK1 -8587
KRAS -7961
B2M -7892
HLA-E -7859
HRAS -7726
LCP2 -6842
RAC1 -6469
PLCG2 -6119
GRB2 -5215
PIK3R1 -4826
PIK3CA -4471
PIK3R2 -3341
FYN -804
VAV3 -548
PIK3CB 1073
LAT 3092
SHC1 4832
LCK 6595
SOS1 7541
VAV2 9364
TREM2 10334


REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS

REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS
176
set REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS
setSize 127
pANOVA 0.00482
s.dist -0.145
p.adjustANOVA 0.171



Top enriched genes

Top 20 genes
GeneID Gene Rank
PSMB11 -10777
CDK9 -10699
TPR -10116
UBB -9922
CD28 -9503
ELOB -9480
SEM1 -9467
APOBEC3G -9198
NUP50 -9137
PSMD14 -8863
CD247 -8686
RAN -8481
ARF1 -8415
NUP42 -8147
XPO1 -8068
PAK2 -7893
B2M -7892
HMGA1 -7648
NUP98 -7640
NUP62 -7441

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PSMB11 -10777
CDK9 -10699
TPR -10116
UBB -9922
CD28 -9503
ELOB -9480
SEM1 -9467
APOBEC3G -9198
NUP50 -9137
PSMD14 -8863
CD247 -8686
RAN -8481
ARF1 -8415
NUP42 -8147
XPO1 -8068
PAK2 -7893
B2M -7892
HMGA1 -7648
NUP98 -7640
NUP62 -7441
SEH1L -7114
PSMD9 -6945
NUP160 -6888
NDC1 -6638
NUP205 -6549
NUP58 -6523
PSMB8 -6491
RAC1 -6469
NUP37 -6122
PSMA8 -6030
RPS27A -5865
PSMD13 -5830
KPNA1 -5788
RANBP1 -5762
PSME4 -5742
RBX1 -5685
PSMD11 -5394
CD4 -5234
PSMB3 -5218
PSIP1 -5188
NUP210 -5101
NUP153 -5090
RANGAP1 -5063
PPIA -4974
AP2A1 -4922
NUP107 -4906
HLA-A -4587
BANF1 -4441
AP2B1 -4349
PSMB5 -4259
PSME2 -4065
PSMD2 -3966
UBC -3937
RCC1 -3906
SLC25A4 -3772
PSMB4 -3508
PACS1 -3465
NUP43 -3319
NUP35 -3128
PSMD5 -2953
PSMB7 -2811
PSMC5 -2753
AP1S1 -2727
CCNT1 -2694
PSMD3 -2367
NUP214 -2260
KPNB1 -2017
NPM1 -1969
AP1M2 -1967
PSMD6 -1831
NUP93 -1824
AP1G1 -1501
PSMD7 -1362
FYN -804
NUP54 -626
CUL5 -510
ELOC -362
PSMA1 -272
BTRC -91
PSME1 -45
PSMC2 97
PSMD1 215
ELMO1 331
NUP155 699
PSMB6 781
POM121C 1437
DOCK2 1482
AP1M1 1624
PSMA7 1653
PSMA3 1747
AP1S3 1798
PSMA2 1886
NUP188 1951
AP1B1 2617
POM121 2707
SEC13 2762
AP2S1 2792
ATP6V1H 2807
PSMB9 2951
AP2A2 3233
PSMA6 3500
AAAS 3650
PSMC6 3773
RANBP2 4244
PSME3 4494
PSMC3 4583
AP2M1 4621
PSMB2 4923
NUP85 5382
PSMB1 5472
PSMC1 5640
PSMD8 5747
RAE1 6150
PSMB10 6504
HCK 6570
LCK 6595
PSMA4 7118
PSMD4 7146
NUP133 7196
PSMC4 7533
CD8B 8024
SKP1 8064
PSMA5 8306
PSMF1 8543
UBA52 8631
NUP88 8810
PSMD12 9475


REACTOME_INTERLEUKIN_35_SIGNALLING

REACTOME_INTERLEUKIN_35_SIGNALLING
1349
set REACTOME_INTERLEUKIN_35_SIGNALLING
setSize 12
pANOVA 0.00494
s.dist -0.469
p.adjustANOVA 0.171



Top enriched genes

Top 20 genes
GeneID Gene Rank
STAT4 -8728
IL12RB2 -8486
EBI3 -8344
JAK2 -8304
JAK1 -7873
IL12A -6607
TYK2 -5493
STAT1 -5422
STAT3 -5158
CANX -2679
IL6ST 144
IL27RA 4541

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
STAT4 -8728
IL12RB2 -8486
EBI3 -8344
JAK2 -8304
JAK1 -7873
IL12A -6607
TYK2 -5493
STAT1 -5422
STAT3 -5158
CANX -2679
IL6ST 144
IL27RA 4541


REACTOME_THE_CITRIC_ACID_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT

REACTOME_THE_CITRIC_ACID_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT
104
set REACTOME_THE_CITRIC_ACID_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT
setSize 159
pANOVA 0.00506
s.dist -0.129
p.adjustANOVA 0.171



Top enriched genes

Top 20 genes
GeneID Gene Rank
ETFB -10764
COQ10A -10445
BSG -10255
ATP5PO -9976
VDAC1 -9974
NDUFS3 -9845
NDUFA3 -9810
CYC1 -9805
ATP5MF -9554
COX14 -9239
LRPPRC -9237
NDUFA10 -9206
TIMMDC1 -9199
ATP5MC3 -9195
ATP5F1E -9095
PDHX -8920
PDPR -8693
ADHFE1 -8564
L2HGDH -8516
IDH3A -8408

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ETFB -10764
COQ10A -10445
BSG -10255
ATP5PO -9976
VDAC1 -9974
NDUFS3 -9845
NDUFA3 -9810
CYC1 -9805
ATP5MF -9554
COX14 -9239
LRPPRC -9237
NDUFA10 -9206
TIMMDC1 -9199
ATP5MC3 -9195
ATP5F1E -9095
PDHX -8920
PDPR -8693
ADHFE1 -8564
L2HGDH -8516
IDH3A -8408
UQCRH -8208
NDUFS7 -8112
PDP1 -8089
PDK4 -7920
CS -7800
COX4I1 -7799
NDUFB7 -7458
SCO1 -7450
ATP5F1D -7379
NDUFB2 -7294
UCP3 -7209
NDUFB9 -7133
COQ10B -6802
LDHAL6A -6701
DMAC2L -6693
NDUFA4 -6560
UCP2 -6552
NDUFA2 -6524
MDH2 -6452
COX8A -6387
ATP5F1B -6375
SDHA -6203
UQCRQ -6125
SURF1 -5836
ATP5F1A -5641
NDUFB3 -5162
SCO2 -5150
TACO1 -5086
ECSIT -5082
SUCLG2 -5009
NDUFA12 -4535
COX20 -4501
PDK1 -4472
COX19 -4420
NDUFA7 -4339
ATP5MC2 -4260
COX7A2L -4201
MPC2 -4141
UQCRFS1 -3799
FAHD1 -3689
ME3 -3679
SLC16A3 -3678
PDK2 -3524
NDUFV3 -3483
COX11 -3478
NDUFB5 -3366
NDUFB6 -3171
COX6A1 -3025
OGDH -2985
NDUFS5 -2853
NDUFB8 -2605
LDHB -2449
IDH2 -2368
DLAT -2102
NDUFV1 -2041
NDUFV2 -2027
NDUFA13 -1897
SLC16A1 -1848
IDH3B -1775
PM20D1 -1677
PDP2 -1596
FH -1439
GLO1 -1257
LDHA -1176
UQCRB -1160
PDHB -1142
UQCRC1 -999
SLC25A27 -889
DLST -582
COX18 -534
TMEM126B -530
NNT -406
GSTZ1 -368
ATP5PB -306
NDUFC2 -303
NDUFB4 -288
UQCR11 -87
SUCLA2 -53
ATP5PD 23
NUBPL 55
NDUFA9 76
ETFA 371
SLC16A8 383
UQCR10 485
ATP5F1C 505
TRAP1 569
ACAD9 578
ME2 861
D2HGDH 938
COA1 995
PPARD 1034
MPC1 1187
ATP5ME 1269
HAGH 1282
NDUFAB1 1428
NDUFS2 1657
NDUFAF7 2296
COX16 2376
SDHD 2390
CYCS 2521
NDUFAF5 2523
UQCRC2 3055
NDUFB1 3057
ETFDH 3583
COX7C 3686
COX5A 3940
ACO2 4067
NDUFS4 4603
NDUFA5 4691
NDUFA11 4742
NDUFS8 5302
NDUFA8 5317
NDUFAF2 5404
SDHB 5625
ME1 5694
ATP5MG 5779
NDUFS1 5782
UCP1 6033
LDHC 6083
COX6C 6211
NDUFAF3 6510
PDHA2 6565
NDUFAF4 6605
NDUFA6 6648
RXRA 6789
NDUFB10 6792
TMEM186 7052
COX6B1 7082
ATP5MC1 7095
ATP5PF 7388
SUCLG1 7400
NDUFC1 7838
COX5B 8356
NDUFS6 8667
DLD 8669
NDUFAF6 9469
NDUFAF1 9538
SDHC 9720
LDHAL6B 10530


REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION

REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION
1636
set REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION
setSize 361
pANOVA 0.00519
s.dist -0.0856
p.adjustANOVA 0.171



Top enriched genes

Top 20 genes
GeneID Gene Rank
PDIA3 -11024
SPSB2 -10810
PSMB11 -10777
RNF126 -10768
ZNRF1 -10751
FBXL12 -10719
HLA-F -10607
RNF123 -10351
ATG14 -10343
UBA7 -10332
KEAP1 -10320
FBXL4 -10162
UBE2J1 -10125
SMURF2 -10094
UBE2D2 -9963
UBE2S -9950
RBCK1 -9943
UBB -9922
HECTD2 -9667
DTX3L -9604

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PDIA3 -11024
SPSB2 -10810
PSMB11 -10777
RNF126 -10768
ZNRF1 -10751
FBXL12 -10719
HLA-F -10607
RNF123 -10351
ATG14 -10343
UBA7 -10332
KEAP1 -10320
FBXL4 -10162
UBE2J1 -10125
SMURF2 -10094
UBE2D2 -9963
UBE2S -9950
RBCK1 -9943
UBB -9922
HECTD2 -9667
DTX3L -9604
ELOB -9480
SEM1 -9467
FZR1 -9437
TRIM41 -9360
HLA-B -9281
FBXW5 -9246
STUB1 -9156
UBE2H -9141
CYBA -9072
CD14 -9030
TRIM21 -8944
ANAPC2 -8906
MIB2 -8889
PSMD14 -8863
FBXO27 -8707
UBE4A -8649
FBXL18 -8644
MEX3C -8565
KLHL2 -8546
ZBTB16 -8509
ZNRF2 -8355
FGA -8302
FBXL5 -8232
ARIH2 -8199
FBXO7 -8176
SIAH2 -7934
BLMH -7901
B2M -7892
HLA-E -7859
LRRC41 -7785
FBXL7 -7722
HECTD1 -7697
CTSL -7633
LTN1 -7371
ASB3 -7279
KLHL3 -6953
PSMD9 -6945
SOCS1 -6887
RBBP6 -6712
CDC16 -6705
CDC34 -6641
FBXO4 -6630
BTBD6 -6576
TRIM4 -6535
RNF182 -6503
PSMB8 -6491
UBR1 -6444
FBXL16 -6380
ASB5 -6378
SEC24C -6368
CBLB -6316
UBE2J2 -6301
KBTBD7 -6288
TAPBP -6259
FBXO9 -6167
GLMN -6107
PSMA8 -6030
RNF19B -6024
UBE2F -5984
DCAF1 -5947
RNF130 -5929
RPS27A -5865
ANAPC7 -5847
RNF41 -5837
PSMD13 -5830
FBXW9 -5787
CTSS -5784
UBR4 -5751
PSME4 -5742
RBX1 -5685
UBE2Z -5616
S100A1 -5579
UBE2K -5542
UBE2R2 -5527
HACE1 -5459
KCTD7 -5447
VAMP8 -5399
PSMD11 -5394
CDC23 -5346
BECN1 -5275
NCF4 -5274
LNPEP -5237
PSMB3 -5218
KLHL5 -5207
FBXO30 -5180
UBE2L6 -5084
UBE2D3 -5052
FGB -5023
TRIM69 -4689
ASB8 -4676
KCTD6 -4666
IKBKB -4657
SEC23A -4621
TRIM11 -4596
FBXL15 -4588
HLA-A -4587
RCHY1 -4487
FBXO6 -4416
TAP1 -4415
ASB16 -4318
PSMB5 -4259
RNF25 -4257
HERC1 -4204
FBXW4 -4161
CHUK -4148
SEC61A2 -4120
PSME2 -4065
PSMD2 -3966
HSPA5 -3955
UBC -3937
HECW2 -3901
FBXW8 -3898
HERC4 -3856
KLHL20 -3837
CTSV -3710
PSMB4 -3508
ANAPC5 -3480
HMGB1 -3434
LY96 -3240
UBE2Q1 -3057
UBE2E1 -3038
PSMD5 -2953
BTBD1 -2884
FBXO31 -2880
PIK3C3 -2844
FBXO41 -2815
PSMB7 -2811
PSMC5 -2753
THOP1 -2712
CANX -2679
RNF4 -2662
UBE3A -2457
SH3RF1 -2425
UBE2O -2424
TRAIP -2386
TLR2 -2381
FBXO17 -2375
PSMD3 -2367
VAMP3 -2340
LMO7 -2331
UBE2M -2239
GAN -2225
SEC22B -2142
FBXL8 -2044
UBR2 -2023
ERAP1 -2010
TRIM36 -1907
MKRN1 -1832
PSMD6 -1831
DET1 -1815
UBE2G2 -1752
MGRN1 -1732
TLR4 -1666
UBAC1 -1662
SOCS3 -1657
UNKL -1545
UBE2N -1518
RNF6 -1500
DZIP3 -1496
RNF19A -1495
UBE3B -1462
ANAPC1 -1451
KLHL25 -1375
PSMD7 -1362
TPP2 -1270
RNF213 -1235
PIK3R4 -1175
UBA6 -1148
AREL1 -1114
FBXW11 -1101
RNF111 -1036
ATG7 -989
UBOX5 -956
TRIP12 -919
CDC26 -850
TRAF7 -780
KLHL22 -764
HERC6 -719
NPEPPS -710
LRSAM1 -700
CUL5 -510
ELOC -362
SMURF1 -320
TRIM71 -297
PSMA1 -272
UBE2G1 -265
LONRF1 -239
ASB18 -213
BTRC -91
CCNF -54
PSME1 -45
PSMC2 97
RNF115 111
UBE3C 210
PSMD1 215
ANAPC11 264
ITGAV 384
KLHL11 488
FBXW7 534
SAR1B 571
ASB13 622
PSMB6 781
SPSB4 910
KLHL9 1033
ERAP2 1039
ASB6 1041
FBXL14 1045
HERC5 1047
RNF114 1117
FBXL19 1224
UBA3 1249
RNF138 1454
TRIM37 1459
FBXO22 1575
SEC61A1 1633
PSMA7 1653
MYLIP 1687
NEDD4 1707
PSMA3 1747
PSMA2 1886
PRKN 1954
CDC20 2128
RNF34 2132
FBXO15 2144
SEC61B 2160
ASB15 2164
FBXL22 2177
ANAPC4 2282
FBXL3 2438
TRIM9 2549
CD36 2576
MYD88 2621
UBE3D 2651
FBXO11 2667
KLHL42 2668
FBXO21 2719
SEC13 2762
ANAPC10 2777
TRIM32 2856
FGG 2888
PSMB9 2951
SEC31A 2983
ASB1 2997
UBE2W 3222
UBE2E3 3297
UBE2B 3450
ASB7 3499
PSMA6 3500
PSMC6 3773
WWP1 3793
UBE2L3 3798
WSB1 3881
STX4 3883
HLA-G 3890
UBE2V2 3951
RNF220 3987
SPSB1 4117
UFL1 4160
FBXO32 4332
TAP2 4429
PSME3 4494
FBXL13 4520
PJA2 4526
FBXW2 4554
PSMC3 4583
KLHL21 4627
FBXL20 4689
HECTD3 4725
HLA-C 4768
CUL3 4884
SEC24A 4899
PSMB2 4923
TRIM63 5099
MRC2 5170
UBA5 5184
UBE2E2 5201
UBE2D4 5251
FBXO2 5403
HERC3 5408
SNAP23 5418
LRR1 5446
PSMB1 5472
CD207 5483
CUL1 5560
PSMC1 5640
SIAH1 5739
PSMD8 5747
SKP2 5770
ANAPC13 5828
KLHL41 5916
VHL 6057
CALR 6080
TIRAP 6086
UBE2U 6099
UBE2D1 6123
UBE2C 6168
SEC61G 6256
NCF2 6377
PSMB10 6504
UBE2V1 6602
CUL7 6653
RNF14 6786
ASB17 6818
HERC2 7015
RNF217 7026
PSMA4 7118
PSMD4 7146
SEC24D 7233
TLR6 7273
SEC24B 7429
PSMC4 7533
ITCH 7559
FBXO44 7620
TRIM39 7650
ASB14 7728
CUL2 7902
UBE2Q2 8044
RNF144B 8047
ASB4 8048
SKP1 8064
RNF7 8213
CDC27 8270
PSMA5 8306
NEDD4L 8335
PSMF1 8543
ASB2 8611
UBA52 8631
ASB10 8897
KBTBD8 8936
FBXO10 9149
LNX1 9288
FBXW10 9318
TRIM50 9352
PSMD12 9475
TLR1 9536
FBXO40 9599
KBTBD6 9645
S100A9 9913
ITGB5 10187
FBXW12 10457
S100A8 10862


REACTOME_BUTYROPHILIN_BTN_FAMILY_INTERACTIONS

REACTOME_BUTYROPHILIN_BTN_FAMILY_INTERACTIONS
1228
set REACTOME_BUTYROPHILIN_BTN_FAMILY_INTERACTIONS
setSize 12
pANOVA 0.00527
s.dist 0.465
p.adjustANOVA 0.171



Top enriched genes

Top 20 genes
GeneID Gene Rank
BTN1A1 10288
BTNL8 10230
CD209 10035
BTN3A1 9782
XDH 8999
BTN3A3 8346
BTNL2 7531
BTN2A1 4170
BTN2A2 -713
BTN3A2 -1899
BTNL9 -2327
PPL -3619

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
BTN1A1 10288
BTNL8 10230
CD209 10035
BTN3A1 9782
XDH 8999
BTN3A3 8346
BTNL2 7531
BTN2A1 4170
BTN2A2 -713
BTN3A2 -1899
BTNL9 -2327
PPL -3619


Here is the session info with all the versions of packages used.

sessionInfo()
## R version 4.3.2 (2023-10-31)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.3 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3 
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so;  LAPACK version 3.10.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Etc/UTC
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.3.3                                      
##  [2] GGally_2.2.0                                       
##  [3] ggplot2_3.4.4                                      
##  [4] reshape2_1.4.4                                     
##  [5] gtools_3.9.5                                       
##  [6] tibble_3.2.1                                       
##  [7] dplyr_1.1.4                                        
##  [8] echarts4r_0.4.5                                    
##  [9] png_0.1-8                                          
## [10] gridExtra_2.3                                      
## [11] missMethyl_1.36.0                                  
## [12] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.1 
## [13] beeswarm_0.4.0                                     
## [14] kableExtra_1.3.4                                   
## [15] gplots_3.1.3                                       
## [16] mitch_1.15.0                                       
## [17] tictoc_1.2                                         
## [18] HGNChelper_0.8.1                                   
## [19] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [20] IlluminaHumanMethylation450kmanifest_0.4.0         
## [21] minfi_1.48.0                                       
## [22] bumphunter_1.44.0                                  
## [23] locfit_1.5-9.8                                     
## [24] iterators_1.0.14                                   
## [25] foreach_1.5.2                                      
## [26] Biostrings_2.70.1                                  
## [27] XVector_0.42.0                                     
## [28] SummarizedExperiment_1.32.0                        
## [29] Biobase_2.62.0                                     
## [30] MatrixGenerics_1.14.0                              
## [31] matrixStats_1.2.0                                  
## [32] GenomicRanges_1.54.1                               
## [33] GenomeInfoDb_1.38.2                                
## [34] IRanges_2.36.0                                     
## [35] S4Vectors_0.40.2                                   
## [36] BiocGenerics_0.48.1                                
## [37] eulerr_7.0.0                                       
## [38] limma_3.58.1                                       
## 
## loaded via a namespace (and not attached):
##   [1] splines_4.3.2             later_1.3.2              
##   [3] BiocIO_1.12.0             bitops_1.0-7             
##   [5] filelock_1.0.3            preprocessCore_1.64.0    
##   [7] XML_3.99-0.16             lifecycle_1.0.4          
##   [9] lattice_0.22-5            MASS_7.3-60              
##  [11] base64_2.0.1              scrime_1.3.5             
##  [13] magrittr_2.0.3            sass_0.4.8               
##  [15] rmarkdown_2.25            jquerylib_0.1.4          
##  [17] yaml_2.3.8                httpuv_1.6.13            
##  [19] doRNG_1.8.6               askpass_1.2.0            
##  [21] DBI_1.1.3                 RColorBrewer_1.1-3       
##  [23] abind_1.4-5               zlibbioc_1.48.0          
##  [25] rvest_1.0.3               quadprog_1.5-8           
##  [27] purrr_1.0.2               RCurl_1.98-1.13          
##  [29] rappdirs_0.3.3            GenomeInfoDbData_1.2.11  
##  [31] genefilter_1.84.0         annotate_1.80.0          
##  [33] svglite_2.1.3             DelayedMatrixStats_1.24.0
##  [35] codetools_0.2-19          DelayedArray_0.28.0      
##  [37] xml2_1.3.6                tidyselect_1.2.0         
##  [39] beanplot_1.3.1            BiocFileCache_2.10.1     
##  [41] webshot_0.5.5             illuminaio_0.44.0        
##  [43] GenomicAlignments_1.38.0  jsonlite_1.8.8           
##  [45] multtest_2.58.0           ellipsis_0.3.2           
##  [47] survival_3.5-7            systemfonts_1.0.5        
##  [49] tools_4.3.2               progress_1.2.3           
##  [51] Rcpp_1.0.11               glue_1.6.2               
##  [53] SparseArray_1.2.2         xfun_0.41                
##  [55] HDF5Array_1.30.0          withr_2.5.2              
##  [57] fastmap_1.1.1             rhdf5filters_1.14.1      
##  [59] fansi_1.0.6               openssl_2.1.1            
##  [61] caTools_1.18.2            digest_0.6.33            
##  [63] R6_2.5.1                  mime_0.12                
##  [65] colorspace_2.1-0          biomaRt_2.58.0           
##  [67] RSQLite_2.3.4             utf8_1.2.4               
##  [69] tidyr_1.3.0               generics_0.1.3           
##  [71] data.table_1.14.10        rtracklayer_1.62.0       
##  [73] prettyunits_1.2.0         httr_1.4.7               
##  [75] htmlwidgets_1.6.4         S4Arrays_1.2.0           
##  [77] ggstats_0.5.1             pkgconfig_2.0.3          
##  [79] gtable_0.3.4              blob_1.2.4               
##  [81] siggenes_1.76.0           htmltools_0.5.7          
##  [83] scales_1.3.0              rstudioapi_0.15.0        
##  [85] knitr_1.45                tzdb_0.4.0               
##  [87] rjson_0.2.21              nlme_3.1-163             
##  [89] curl_5.2.0                org.Hs.eg.db_3.18.0      
##  [91] cachem_1.0.8              rhdf5_2.46.1             
##  [93] stringr_1.5.1             KernSmooth_2.23-22       
##  [95] AnnotationDbi_1.64.1      restfulr_0.0.15          
##  [97] GEOquery_2.70.0           pillar_1.9.0             
##  [99] grid_4.3.2                reshape_0.8.9            
## [101] vctrs_0.6.5               promises_1.2.1           
## [103] dbplyr_2.4.0              xtable_1.8-4             
## [105] evaluate_0.23             readr_2.1.4              
## [107] GenomicFeatures_1.54.1    cli_3.6.2                
## [109] compiler_4.3.2            Rsamtools_2.18.0         
## [111] rlang_1.1.2               crayon_1.5.2             
## [113] rngtools_1.5.2            nor1mix_1.3-2            
## [115] mclust_6.0.1              plyr_1.8.9               
## [117] stringi_1.8.3             viridisLite_0.4.2        
## [119] BiocParallel_1.36.0       munsell_0.5.0            
## [121] Matrix_1.6-1.1            hms_1.1.3                
## [123] sparseMatrixStats_1.14.0  bit64_4.0.5              
## [125] Rhdf5lib_1.24.1           KEGGREST_1.42.0          
## [127] statmod_1.5.0             shiny_1.8.0              
## [129] highr_0.10                memoise_2.0.1            
## [131] bslib_0.6.1               bit_4.0.5

END of report