Mitch Report

date generated: 2024-01-18

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch

	x
A1BG	0.0011774
A1BG-AS1	0.0013470
A1CF	-0.0019445
A2M	-0.0008272
A2M-AS1	0.0026419
A2ML1	-0.0010378

Here are some metrics about the input data profile:

Profiling data metrics

	Profile metrics
num_genesets	1654
num_genes_in_profile	22007
duplicated_genes_present	0
num_profile_genes_in_sets	10383
num_profile_genes_not_in_sets	11624

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets: c2.cp.reactome.v2023.1.Hs.symbols.gmt

Gene set metrics

	Gene sets metrics
num_genesets	1654
num_genesets_excluded	365
num_genesets_included	1289

Differential pathway expression

Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

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## in kable. kableExtra can customize either HTML or LaTeX outputs. See
## https://haozhu233.github.io/kableExtra/ for details.

set	setSize	pANOVA	s.dist	p.adjustANOVA
REACTOME METABOLISM OF RNA	675	1.10e-35	0.281	1.80e-32
REACTOME RNA POLYMERASE II TRANSCRIPTION	1336	1.24e-30	0.187	1.02e-27
REACTOME CELL CYCLE	666	5.82e-29	0.253	3.19e-26
REACTOME CELL CYCLE MITOTIC	539	2.40e-25	0.262	9.86e-23
REACTOME KERATINIZATION	210	8.50e-24	-0.402	2.79e-21
REACTOME INFECTIOUS DISEASE	910	1.24e-20	0.182	3.32e-18
REACTOME SENSORY PERCEPTION	555	1.41e-20	-0.231	3.32e-18
REACTOME M PHASE	398	3.57e-20	0.268	7.32e-18
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	263	6.90e-20	0.327	1.26e-17
REACTOME CELLULAR RESPONSES TO STIMULI	779	1.88e-18	0.184	3.08e-16
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION	1356	8.74e-18	0.139	1.24e-15
REACTOME HIV INFECTION	223	9.07e-18	0.333	1.24e-15
REACTOME TRANSCRIPTIONAL REGULATION BY TP53	351	1.09e-17	0.266	1.38e-15
REACTOME CHROMATIN MODIFYING ENZYMES	252	2.85e-17	0.309	3.35e-15
REACTOME OLFACTORY SIGNALING PATHWAY	348	8.36e-17	-0.260	9.15e-15
REACTOME CELL CYCLE CHECKPOINTS	284	1.77e-15	0.274	1.82e-13
REACTOME FORMATION OF THE CORNIFIED ENVELOPE	125	5.73e-15	-0.404	5.54e-13
REACTOME DNA REPAIR	321	9.65e-15	0.251	8.80e-13
REACTOME DEUBIQUITINATION	260	2.18e-13	0.264	1.88e-11
REACTOME MRNA SPLICING	197	2.93e-13	0.301	2.40e-11
REACTOME MITOTIC METAPHASE AND ANAPHASE	228	1.02e-12	0.274	7.97e-11
REACTOME HOST INTERACTIONS OF HIV FACTORS	127	5.74e-12	0.354	4.29e-10
REACTOME NEURONAL SYSTEM	388	9.22e-12	-0.202	6.58e-10
REACTOME HATS ACETYLATE HISTONES	129	3.12e-11	0.338	2.13e-09
REACTOME MEMBRANE TRAFFICKING	603	3.93e-11	0.157	2.58e-09
REACTOME SEPARATION OF SISTER CHROMATIDS	184	8.97e-11	0.277	5.66e-09
REACTOME S PHASE	159	1.02e-10	0.297	6.04e-09
REACTOME RHO GTPASE EFFECTORS	305	1.03e-10	0.215	6.04e-09
REACTOME GPCR LIGAND BINDING	444	1.10e-10	-0.179	6.11e-09
REACTOME UCH PROTEINASES	99	1.12e-10	0.375	6.11e-09
REACTOME HIV LIFE CYCLE	145	1.21e-10	0.310	6.36e-09
REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS	188	1.24e-10	0.272	6.36e-09
REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	296	1.35e-10	0.217	6.72e-09
REACTOME UB SPECIFIC PROCESSING PROTEASES	187	2.05e-10	0.269	9.90e-09
REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3	679	2.72e-10	0.142	1.27e-08
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION	361	6.38e-10	0.189	2.91e-08
REACTOME ADAPTIVE IMMUNE SYSTEM	729	7.69e-10	0.134	3.36e-08
REACTOME TRANSLATION	278	7.78e-10	0.214	3.36e-08
REACTOME DNA REPLICATION	178	2.22e-09	0.260	9.35e-08
REACTOME DNA REPLICATION PRE INITIATION	150	2.74e-09	0.281	1.13e-07
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1	229	2.89e-09	0.228	1.16e-07
REACTOME REGULATION OF TP53 ACTIVITY	156	2.97e-09	0.275	1.16e-07
REACTOME SYNTHESIS OF DNA	119	3.92e-09	0.312	1.50e-07
REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE	277	5.10e-09	0.204	1.90e-07
REACTOME PTEN REGULATION	135	7.19e-09	0.288	2.62e-07
REACTOME TRNA PROCESSING	105	8.46e-09	0.325	3.02e-07
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION	138	8.71e-09	0.284	3.04e-07
REACTOME GENE SILENCING BY RNA	133	1.10e-08	0.287	3.76e-07
REACTOME MITOTIC SPINDLE CHECKPOINT	109	1.14e-08	0.316	3.82e-07
REACTOME MITOTIC PROMETAPHASE	194	1.37e-08	0.236	4.50e-07

---

Results (complete table)

Click HERE to show results for all gene sets

Complete results

set	setSize	pANOVA	s.dist	p.adjustANOVA
REACTOME METABOLISM OF RNA	675	1.10e-35	0.281000	1.80e-32
REACTOME RNA POLYMERASE II TRANSCRIPTION	1336	1.24e-30	0.187000	1.02e-27
REACTOME CELL CYCLE	666	5.82e-29	0.253000	3.19e-26
REACTOME CELL CYCLE MITOTIC	539	2.40e-25	0.262000	9.86e-23
REACTOME KERATINIZATION	210	8.50e-24	-0.402000	2.79e-21
REACTOME INFECTIOUS DISEASE	910	1.24e-20	0.182000	3.32e-18
REACTOME SENSORY PERCEPTION	555	1.41e-20	-0.231000	3.32e-18
REACTOME M PHASE	398	3.57e-20	0.268000	7.32e-18
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	263	6.90e-20	0.327000	1.26e-17
REACTOME CELLULAR RESPONSES TO STIMULI	779	1.88e-18	0.184000	3.08e-16
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION	1356	8.74e-18	0.139000	1.24e-15
REACTOME HIV INFECTION	223	9.07e-18	0.333000	1.24e-15
REACTOME TRANSCRIPTIONAL REGULATION BY TP53	351	1.09e-17	0.266000	1.38e-15
REACTOME CHROMATIN MODIFYING ENZYMES	252	2.85e-17	0.309000	3.35e-15
REACTOME OLFACTORY SIGNALING PATHWAY	348	8.36e-17	-0.260000	9.15e-15
REACTOME CELL CYCLE CHECKPOINTS	284	1.77e-15	0.274000	1.82e-13
REACTOME FORMATION OF THE CORNIFIED ENVELOPE	125	5.73e-15	-0.404000	5.54e-13
REACTOME DNA REPAIR	321	9.65e-15	0.251000	8.80e-13
REACTOME DEUBIQUITINATION	260	2.18e-13	0.264000	1.88e-11
REACTOME MRNA SPLICING	197	2.93e-13	0.301000	2.40e-11
REACTOME MITOTIC METAPHASE AND ANAPHASE	228	1.02e-12	0.274000	7.97e-11
REACTOME HOST INTERACTIONS OF HIV FACTORS	127	5.74e-12	0.354000	4.29e-10
REACTOME NEURONAL SYSTEM	388	9.22e-12	-0.202000	6.58e-10
REACTOME HATS ACETYLATE HISTONES	129	3.12e-11	0.338000	2.13e-09
REACTOME MEMBRANE TRAFFICKING	603	3.93e-11	0.157000	2.58e-09
REACTOME SEPARATION OF SISTER CHROMATIDS	184	8.97e-11	0.277000	5.66e-09
REACTOME S PHASE	159	1.02e-10	0.297000	6.04e-09
REACTOME RHO GTPASE EFFECTORS	305	1.03e-10	0.215000	6.04e-09
REACTOME GPCR LIGAND BINDING	444	1.10e-10	-0.179000	6.11e-09
REACTOME UCH PROTEINASES	99	1.12e-10	0.375000	6.11e-09
REACTOME HIV LIFE CYCLE	145	1.21e-10	0.310000	6.36e-09
REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS	188	1.24e-10	0.272000	6.36e-09
REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	296	1.35e-10	0.217000	6.72e-09
REACTOME UB SPECIFIC PROCESSING PROTEASES	187	2.05e-10	0.269000	9.90e-09
REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3	679	2.72e-10	0.142000	1.27e-08
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION	361	6.38e-10	0.189000	2.91e-08
REACTOME ADAPTIVE IMMUNE SYSTEM	729	7.69e-10	0.134000	3.36e-08
REACTOME TRANSLATION	278	7.78e-10	0.214000	3.36e-08
REACTOME DNA REPLICATION	178	2.22e-09	0.260000	9.35e-08
REACTOME DNA REPLICATION PRE INITIATION	150	2.74e-09	0.281000	1.13e-07
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1	229	2.89e-09	0.228000	1.16e-07
REACTOME REGULATION OF TP53 ACTIVITY	156	2.97e-09	0.275000	1.16e-07
REACTOME SYNTHESIS OF DNA	119	3.92e-09	0.312000	1.50e-07
REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE	277	5.10e-09	0.204000	1.90e-07
REACTOME PTEN REGULATION	135	7.19e-09	0.288000	2.62e-07
REACTOME TRNA PROCESSING	105	8.46e-09	0.325000	3.02e-07
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION	138	8.71e-09	0.284000	3.04e-07
REACTOME GENE SILENCING BY RNA	133	1.10e-08	0.287000	3.76e-07
REACTOME MITOTIC SPINDLE CHECKPOINT	109	1.14e-08	0.316000	3.82e-07
REACTOME MITOTIC PROMETAPHASE	194	1.37e-08	0.236000	4.50e-07
REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	86	1.41e-08	0.354000	4.55e-07
REACTOME SIGNALING BY NOTCH	234	1.48e-08	0.215000	4.64e-07
REACTOME SIGNALING BY WNT	318	1.50e-08	0.185000	4.64e-07
REACTOME G2 M CHECKPOINTS	162	1.90e-08	0.256000	5.78e-07
REACTOME VESICLE MEDIATED TRANSPORT	642	2.32e-08	0.129000	6.91e-07
REACTOME ASPARAGINE N LINKED GLYCOSYLATION	299	2.37e-08	0.188000	6.95e-07
REACTOME DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX	83	2.46e-08	0.354000	7.10e-07
REACTOME KEAP1 NFE2L2 PATHWAY	104	2.58e-08	0.316000	7.19e-07
REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	78	2.58e-08	0.365000	7.19e-07
REACTOME MITOTIC G2 G2 M PHASES	194	2.69e-08	0.231000	7.36e-07
REACTOME SUMOYLATION	179	2.77e-08	0.241000	7.46e-07
REACTOME SARS COV INFECTIONS	392	2.84e-08	0.163000	7.53e-07
REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS	418	3.17e-08	0.158000	8.27e-07
REACTOME SIGNALING BY THE B CELL RECEPTOR BCR	106	3.24e-08	0.311000	8.31e-07
REACTOME HCMV LATE EVENTS	110	3.99e-08	0.303000	1.01e-06
REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS	312	5.18e-08	-0.179000	1.29e-06
REACTOME INNATE IMMUNE SYSTEM	1002	5.59e-08	0.101000	1.37e-06
REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT	159	6.41e-08	0.248000	1.55e-06
REACTOME REGULATION OF RUNX3 EXPRESSION AND ACTIVITY	54	6.51e-08	0.425000	1.55e-06
REACTOME NEDDYLATION	235	8.98e-08	0.202000	2.11e-06
REACTOME EXTRACELLULAR MATRIX ORGANIZATION	291	1.43e-07	-0.179000	3.30e-06
REACTOME NUCLEAR EVENTS MEDIATED BY NFE2L2	77	1.45e-07	0.347000	3.31e-06
REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION	98	1.83e-07	0.305000	4.11e-06
REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	73	2.46e-07	0.349000	5.46e-06
REACTOME BETA CATENIN INDEPENDENT WNT SIGNALING	145	3.18e-07	0.246000	6.97e-06
REACTOME SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE	91	3.50e-07	0.309000	7.57e-06
REACTOME PCP CE PATHWAY	91	3.58e-07	0.309000	7.64e-06
REACTOME ESR MEDIATED SIGNALING	210	3.71e-07	0.203000	7.78e-06
REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS	100	3.74e-07	0.294000	7.78e-06
REACTOME SIGNALING BY GPCR	673	3.80e-07	-0.115000	7.79e-06
REACTOME DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING	61	4.44e-07	0.374000	8.98e-06
REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	79	4.48e-07	0.328000	8.98e-06
REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION	145	4.55e-07	0.243000	9.01e-06
REACTOME DEGRADATION OF GLI1 BY THE PROTEASOME	59	4.82e-07	0.379000	9.43e-06
REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT	222	5.30e-07	0.195000	1.02e-05
REACTOME AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA	54	5.51e-07	0.394000	1.05e-05
REACTOME RAB REGULATION OF TRAFFICKING	110	6.00e-07	0.275000	1.13e-05
REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS	101	6.41e-07	-0.287000	1.20e-05
REACTOME FC EPSILON RECEPTOR FCERI SIGNALING	127	7.08e-07	0.255000	1.31e-05
REACTOME NUCLEOTIDE EXCISION REPAIR	107	7.34e-07	0.277000	1.33e-05
REACTOME SIGNALING BY NOTCH4	80	7.36e-07	0.320000	1.33e-05
REACTOME MITOTIC PROPHASE	134	7.71e-07	0.247000	1.35e-05
REACTOME UNFOLDED PROTEIN RESPONSE UPR	88	7.71e-07	0.305000	1.35e-05
REACTOME TCR SIGNALING	113	7.78e-07	0.269000	1.35e-05
REACTOME RESPIRATORY ELECTRON TRANSPORT	90	7.82e-07	0.301000	1.35e-05
REACTOME APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS	87	8.17e-07	0.306000	1.40e-05
REACTOME CLEC7A DECTIN 1 SIGNALING	97	8.28e-07	0.289000	1.40e-05
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX3	94	8.41e-07	0.294000	1.41e-05
REACTOME CILIUM ASSEMBLY	190	8.47e-07	0.207000	1.41e-05
REACTOME SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS	74	1.11e-06	0.327000	1.82e-05
REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	134	1.13e-06	-0.243000	1.84e-05
REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	111	1.24e-06	0.266000	2.00e-05
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS	121	1.36e-06	0.254000	2.17e-05
REACTOME RNA POLYMERASE I TRANSCRIPTION	102	1.44e-06	0.276000	2.28e-05
REACTOME STABILIZATION OF P53	56	1.54e-06	0.371000	2.41e-05
REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	54	1.64e-06	0.377000	2.55e-05
REACTOME SIGNALING BY NUCLEAR RECEPTORS	283	1.78e-06	0.165000	2.73e-05
REACTOME HCMV INFECTION	152	1.83e-06	0.224000	2.79e-05
REACTOME TRNA PROCESSING IN THE NUCLEUS	58	2.05e-06	0.360000	3.09e-05
REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS	60	2.09e-06	0.354000	3.12e-05
REACTOME SNRNP ASSEMBLY	53	2.18e-06	0.376000	3.23e-05
REACTOME MAPK6 MAPK4 SIGNALING	91	2.23e-06	0.287000	3.26e-05
REACTOME CHROMOSOME MAINTENANCE	130	2.30e-06	0.240000	3.34e-05
REACTOME CARDIAC CONDUCTION	125	2.73e-06	-0.243000	3.93e-05
REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE	93	3.33e-06	0.279000	4.76e-05
REACTOME CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY	84	3.41e-06	0.293000	4.82e-05
REACTOME TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS	43	3.46e-06	0.409000	4.85e-05
REACTOME MUSCLE CONTRACTION	197	3.55e-06	-0.192000	4.92e-05
REACTOME RHO GTPASES ACTIVATE FORMINS	136	3.56e-06	0.230000	4.92e-05
REACTOME NEGATIVE REGULATION OF NOTCH4 SIGNALING	53	4.01e-06	0.366000	5.49e-05
REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION	45	4.25e-06	0.396000	5.76e-05
REACTOME DEGRADATION OF AXIN	54	4.43e-06	0.361000	5.97e-05
REACTOME NEUTROPHIL DEGRANULATION	460	5.42e-06	0.124000	7.23e-05
REACTOME CELLULAR RESPONSE TO HEAT STRESS	99	5.46e-06	0.264000	7.23e-05
REACTOME COLLAGEN DEGRADATION	61	6.13e-06	-0.335000	8.05e-05
REACTOME REGULATION OF PTEN STABILITY AND ACTIVITY	67	6.25e-06	0.319000	8.15e-05
REACTOME ORC1 REMOVAL FROM CHROMATIN	70	6.68e-06	0.311000	8.63e-05
REACTOME INTERLEUKIN 1 SIGNALING	110	6.73e-06	0.248000	8.63e-05
REACTOME SARS COV 2 INFECTION	281	6.89e-06	0.156000	8.77e-05
REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS	68	7.33e-06	0.314000	9.26e-05
REACTOME REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE	81	8.12e-06	0.287000	1.02e-04
REACTOME RNA POLYMERASE II PRE TRANSCRIPTION EVENTS	77	8.20e-06	0.294000	1.02e-04
REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	46	8.61e-06	0.379000	1.06e-04
REACTOME SUMOYLATION OF DNA REPLICATION PROTEINS	46	1.00e-05	0.376000	1.23e-04
REACTOME VIRAL MESSENGER RNA SYNTHESIS	44	1.11e-05	0.383000	1.35e-04
REACTOME DNA DOUBLE STRAND BREAK REPAIR	162	1.21e-05	0.199000	1.46e-04
REACTOME TRANSCRIPTION OF THE HIV GENOME	66	1.26e-05	0.311000	1.52e-04
REACTOME HDACS DEACETYLATE HISTONES	85	1.30e-05	0.274000	1.55e-04
REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION	84	1.33e-05	0.275000	1.58e-04
REACTOME BIOLOGICAL OXIDATIONS	210	1.48e-05	-0.173000	1.74e-04
REACTOME TELOMERE MAINTENANCE	106	1.50e-05	0.243000	1.75e-04
REACTOME METABOLISM OF POLYAMINES	56	1.53e-05	0.334000	1.77e-04
REACTOME BASE EXCISION REPAIR	87	1.66e-05	0.267000	1.91e-04
REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES	77	1.68e-05	-0.284000	1.91e-04
REACTOME DEGRADATION OF DVL	56	1.68e-05	0.332000	1.91e-04
REACTOME HOMOLOGY DIRECTED REPAIR	132	1.75e-05	0.216000	1.97e-04
REACTOME G1 S DNA DAMAGE CHECKPOINTS	67	1.88e-05	0.302000	2.09e-04
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION	29	1.90e-05	0.459000	2.09e-04
REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	63	1.90e-05	-0.311000	2.09e-04
REACTOME MITOCHONDRIAL TRANSLATION	93	1.92e-05	0.256000	2.11e-04
REACTOME FCERI MEDIATED NF KB ACTIVATION	78	2.12e-05	0.278000	2.30e-04
REACTOME ESTROGEN DEPENDENT GENE EXPRESSION	140	2.19e-05	0.208000	2.36e-04
REACTOME TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS	55	2.25e-05	0.330000	2.41e-04
REACTOME RMTS METHYLATE HISTONE ARGININES	72	2.29e-05	0.289000	2.44e-04
REACTOME TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES	61	2.34e-05	0.313000	2.47e-04
REACTOME ASPIRIN ADME	42	2.34e-05	-0.377000	2.47e-04
REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES	78	2.36e-05	0.277000	2.47e-04
REACTOME REGULATION OF LIPID METABOLISM BY PPARALPHA	115	2.39e-05	0.228000	2.48e-04
REACTOME METABOLISM OF LIPIDS	709	2.43e-05	0.093000	2.51e-04
REACTOME C TYPE LECTIN RECEPTORS CLRS	136	2.61e-05	0.209000	2.67e-04
REACTOME PEPTIDE LIGAND BINDING RECEPTORS	188	2.63e-05	-0.178000	2.68e-04
REACTOME RNA POLYMERASE II TRANSCRIBES SNRNA GENES	77	2.73e-05	0.276000	2.77e-04
REACTOME DEADENYLATION DEPENDENT MRNA DECAY	56	2.76e-05	0.324000	2.78e-04
REACTOME TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER	76	2.81e-05	0.278000	2.81e-04
REACTOME TNFR2 NON CANONICAL NF KB PATHWAY	96	2.94e-05	0.247000	2.92e-04
REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION	100	2.95e-05	0.242000	2.92e-04
REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS	299	3.01e-05	0.140000	2.96e-04
REACTOME REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION	84	3.06e-05	0.263000	2.99e-04
REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION	62	3.27e-05	0.305000	3.18e-04
REACTOME DEVELOPMENTAL BIOLOGY	1115	3.72e-05	-0.073200	3.59e-04
REACTOME POTASSIUM CHANNELS	102	3.94e-05	-0.236000	3.79e-04
REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS	63	4.16e-05	0.298000	3.97e-04
REACTOME TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA	36	4.49e-05	0.393000	4.26e-04
REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS	33	4.73e-05	0.409000	4.46e-04
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES	255	4.90e-05	-0.148000	4.57e-04
REACTOME SUMOYLATION OF RNA BINDING PROTEINS	47	4.91e-05	0.342000	4.57e-04
REACTOME SUMOYLATION OF SUMOYLATION PROTEINS	35	4.93e-05	0.396000	4.57e-04
REACTOME PROTEIN LOCALIZATION	153	4.98e-05	0.190000	4.59e-04
REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS	81	5.20e-05	0.260000	4.77e-04
REACTOME SUMOYLATION OF UBIQUITINYLATION PROTEINS	39	5.34e-05	0.374000	4.87e-04
REACTOME AURKA ACTIVATION BY TPX2	69	5.52e-05	0.281000	4.99e-04
REACTOME INTERLEUKIN 1 FAMILY SIGNALING	146	5.53e-05	0.193000	4.99e-04
REACTOME RESOLUTION OF SISTER CHROMATID COHESION	120	5.62e-05	0.213000	5.05e-04
REACTOME TBC RABGAPS	40	6.60e-05	0.365000	5.87e-04
REACTOME ANTIMICROBIAL PEPTIDES	76	6.62e-05	-0.265000	5.87e-04
REACTOME O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS	38	7.08e-05	-0.372000	6.25e-04
REACTOME TRNA AMINOACYLATION	40	7.17e-05	0.363000	6.30e-04
REACTOME IRE1ALPHA ACTIVATES CHAPERONES	48	7.33e-05	0.331000	6.40e-04
REACTOME INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS	37	7.61e-05	0.376000	6.61e-04
REACTOME NEUREXINS AND NEUROLIGINS	51	8.17e-05	-0.319000	7.06e-04
REACTOME CELLULAR RESPONSE TO HYPOXIA	74	8.91e-05	0.263000	7.66e-04
REACTOME RRNA PROCESSING	192	9.04e-05	0.164000	7.73e-04
REACTOME HCMV EARLY EVENTS	128	9.63e-05	0.200000	8.20e-04
REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL	58	9.82e-05	0.296000	8.31e-04
REACTOME PROTEIN UBIQUITINATION	76	1.00e-04	0.258000	8.44e-04
REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	57	1.06e-04	0.297000	8.85e-04
REACTOME MATURATION OF SARS COV 2 SPIKE PROTEIN	35	1.06e-04	0.378000	8.87e-04
REACTOME RNA POLYMERASE I PROMOTER ESCAPE	83	1.08e-04	0.246000	8.97e-04
REACTOME ECM PROTEOGLYCANS	73	1.14e-04	-0.261000	9.37e-04
REACTOME PHASE 0 RAPID DEPOLARISATION	31	1.19e-04	-0.399000	9.66e-04
REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER	81	1.19e-04	0.247000	9.66e-04
REACTOME PRE NOTCH EXPRESSION AND PROCESSING	112	1.19e-04	0.210000	9.66e-04
REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY	72	1.21e-04	0.262000	9.78e-04
REACTOME COLLAGEN CHAIN TRIMERIZATION	42	1.23e-04	-0.342000	9.92e-04
REACTOME RESOLUTION OF ABASIC SITES AP SITES	38	1.30e-04	0.359000	1.04e-03
REACTOME DUAL INCISION IN TC NER	63	1.34e-04	0.278000	1.07e-03
REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21	59	1.53e-04	0.285000	1.21e-03
REACTOME REGULATION OF RAS BY GAPS	66	1.57e-04	0.269000	1.24e-03
REACTOME DRUG ADME	103	1.65e-04	-0.215000	1.30e-03
REACTOME CELL CELL JUNCTION ORGANIZATION	64	1.68e-04	-0.272000	1.31e-03
REACTOME HEDGEHOG LIGAND BIOGENESIS	64	1.69e-04	0.272000	1.32e-03
REACTOME PROGRAMMED CELL DEATH	204	1.81e-04	0.152000	1.40e-03
REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	80	1.91e-04	0.241000	1.46e-03
REACTOME HIV TRANSCRIPTION ELONGATION	42	1.91e-04	0.333000	1.46e-03
REACTOME POTENTIAL THERAPEUTICS FOR SARS	92	1.92e-04	0.225000	1.46e-03
REACTOME NUCLEAR IMPORT OF REV PROTEIN	34	1.92e-04	0.369000	1.46e-03
REACTOME E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS	58	2.10e-04	0.281000	1.59e-03
REACTOME TP53 REGULATES METABOLIC GENES	81	2.25e-04	0.237000	1.69e-03
REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION	90	2.31e-04	0.225000	1.73e-03
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM	688	2.39e-04	0.082100	1.79e-03
REACTOME NUCLEAR PORE COMPLEX NPC DISASSEMBLY	36	2.44e-04	0.353000	1.82e-03
REACTOME CD28 CO STIMULATION	32	2.49e-04	0.374000	1.84e-03
REACTOME TELOMERE C STRAND LAGGING STRAND SYNTHESIS	33	2.56e-04	0.368000	1.88e-03
REACTOME AMINE LIGAND BINDING RECEPTORS	40	2.57e-04	-0.334000	1.88e-03
REACTOME VOLTAGE GATED POTASSIUM CHANNELS	42	2.70e-04	-0.325000	1.97e-03
REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC	198	2.73e-04	0.150000	1.98e-03
REACTOME LATE SARS COV 2 INFECTION EVENTS	67	2.79e-04	0.257000	2.02e-03
REACTOME DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS	19	2.85e-04	0.481000	2.05e-03
REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS	66	3.02e-04	-0.257000	2.17e-03
REACTOME RHO GTPASES ACTIVATE PKNS	86	3.06e-04	0.225000	2.18e-03
REACTOME SARS COV 2 HOST INTERACTIONS	191	3.19e-04	0.151000	2.27e-03
REACTOME ABC TRANSPORTER DISORDERS	76	3.24e-04	0.239000	2.29e-03
REACTOME CYP2E1 REACTIONS	10	3.54e-04	-0.652000	2.49e-03
REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX	85	3.66e-04	0.224000	2.57e-03
REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF	53	3.71e-04	0.283000	2.59e-03
REACTOME PROCESSING OF DNA DOUBLE STRAND BREAK ENDS	93	3.80e-04	0.213000	2.64e-03
REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	35	3.86e-04	0.347000	2.67e-03
REACTOME HEDGEHOG OFF STATE	111	3.88e-04	0.195000	2.68e-03
REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	22	3.96e-04	-0.436000	2.72e-03
REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION	89	3.99e-04	0.217000	2.73e-03
REACTOME HIV TRANSCRIPTION INITIATION	43	4.03e-04	0.312000	2.74e-03
REACTOME XENOBIOTICS	22	4.23e-04	-0.434000	2.87e-03
REACTOME GLYCOLYSIS	70	4.26e-04	0.243000	2.88e-03
REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS	42	4.38e-04	-0.313000	2.95e-03
REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION	68	4.44e-04	0.246000	2.98e-03
REACTOME DNA STRAND ELONGATION	31	4.71e-04	0.363000	3.14e-03
REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	183	4.76e-04	0.150000	3.16e-03
REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX	32	4.78e-04	0.357000	3.16e-03
REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	99	5.09e-04	0.202000	3.35e-03
REACTOME POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION	27	5.27e-04	0.385000	3.46e-03
REACTOME FORMATION OF TC NER PRE INCISION COMPLEX	51	5.50e-04	0.280000	3.60e-03
REACTOME G2 M DNA DAMAGE CHECKPOINT	90	5.62e-04	0.210000	3.67e-03
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER	28	5.69e-04	0.376000	3.69e-03
REACTOME HEDGEHOG ON STATE	85	5.73e-04	0.216000	3.70e-03
REACTOME AUTOPHAGY	144	5.75e-04	0.166000	3.70e-03
REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	35	6.46e-04	0.333000	4.14e-03
REACTOME APOPTOSIS	173	6.92e-04	0.150000	4.42e-03
REACTOME CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA	63	6.96e-04	0.247000	4.43e-03
REACTOME COMPLEX I BIOGENESIS	49	7.64e-04	0.278000	4.84e-03
REACTOME SIGNALING BY CSF1 M CSF IN MYELOID CELLS	30	7.71e-04	0.355000	4.87e-03
REACTOME NCAM1 INTERACTIONS	41	7.97e-04	-0.303000	5.01e-03
REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	118	8.06e-04	-0.179000	5.05e-03
REACTOME CYTOPROTECTION BY HMOX1	59	8.68e-04	0.251000	5.42e-03
REACTOME DISEASES OF PROGRAMMED CELL DEATH	96	8.76e-04	0.196000	5.45e-03
REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	25	8.84e-04	0.384000	5.47e-03
REACTOME MITOCHONDRIAL PROTEIN IMPORT	58	9.09e-04	0.252000	5.61e-03
REACTOME INTEGRIN CELL SURFACE INTERACTIONS	83	9.18e-04	-0.210000	5.65e-03
REACTOME DIGESTION AND ABSORPTION	22	9.28e-04	-0.408000	5.69e-03
REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS	83	9.49e-04	0.210000	5.79e-03
REACTOME NUCLEAR ENVELOPE BREAKDOWN	52	9.78e-04	0.264000	5.95e-03
REACTOME LEISHMANIA INFECTION	156	9.88e-04	0.153000	5.99e-03
REACTOME CELLULAR SENESCENCE	189	1.01e-03	0.139000	6.08e-03
REACTOME ADHERENS JUNCTIONS INTERACTIONS	33	1.06e-03	-0.329000	6.39e-03
REACTOME RNA POLYMERASE III TRANSCRIPTION	41	1.09e-03	0.295000	6.52e-03
REACTOME HDMS DEMETHYLATE HISTONES	40	1.12e-03	0.298000	6.68e-03
REACTOME PARASITE INFECTION	57	1.14e-03	0.249000	6.78e-03
REACTOME DIGESTION	17	1.14e-03	-0.456000	6.78e-03
REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	98	1.18e-03	0.190000	6.99e-03
REACTOME MICRORNA MIRNA BIOGENESIS	25	1.20e-03	0.374000	7.09e-03
REACTOME ER TO GOLGI ANTEROGRADE TRANSPORT	152	1.22e-03	0.152000	7.14e-03
REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	32	1.32e-03	0.328000	7.70e-03
REACTOME SIGNALING BY HEDGEHOG	148	1.33e-03	0.153000	7.73e-03
REACTOME VISUAL PHOTOTRANSDUCTION	93	1.34e-03	-0.192000	7.75e-03
REACTOME NS1 MEDIATED EFFECTS ON HOST PATHWAYS	41	1.35e-03	0.289000	7.81e-03
REACTOME TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS	29	1.36e-03	0.344000	7.81e-03
REACTOME INTERLEUKIN RECEPTOR SHC SIGNALING	24	1.37e-03	0.377000	7.85e-03
REACTOME MRNA SPLICING MINOR PATHWAY	49	1.39e-03	0.264000	7.97e-03
REACTOME MRNA CAPPING	28	1.40e-03	0.349000	8.00e-03
REACTOME TOLL LIKE RECEPTOR 9 TLR9 CASCADE	100	1.48e-03	0.184000	8.43e-03
REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING	45	1.50e-03	0.273000	8.52e-03
REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	76	1.53e-03	0.210000	8.61e-03
REACTOME CIRCADIAN CLOCK	68	1.56e-03	0.222000	8.74e-03
REACTOME SIGNALING BY ROBO RECEPTORS	206	1.56e-03	0.128000	8.74e-03
REACTOME HIV ELONGATION ARREST AND RECOVERY	33	1.56e-03	0.318000	8.74e-03
REACTOME RHO GTPASE CYCLE	423	1.57e-03	0.089600	8.76e-03
REACTOME CELL JUNCTION ORGANIZATION	89	1.58e-03	-0.194000	8.77e-03
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	81	1.61e-03	0.203000	8.89e-03
REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	32	1.63e-03	0.322000	8.97e-03
REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE	63	1.67e-03	0.229000	9.16e-03
REACTOME DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA	77	1.68e-03	0.207000	9.18e-03
REACTOME DEADENYLATION OF MRNA	25	1.70e-03	0.362000	9.29e-03
REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS	43	1.71e-03	0.276000	9.31e-03
REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL	41	1.72e-03	0.283000	9.31e-03
REACTOME INFLUENZA INFECTION	149	1.75e-03	0.149000	9.42e-03
REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	20	1.75e-03	0.404000	9.42e-03
REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP	104	1.76e-03	0.178000	9.44e-03
REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION	23	1.78e-03	-0.376000	9.52e-03
REACTOME DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE	17	1.80e-03	-0.437000	9.58e-03
REACTOME MITOCHONDRIAL BIOGENESIS	87	1.80e-03	0.194000	9.58e-03
REACTOME SCAVENGING BY CLASS A RECEPTORS	19	1.91e-03	-0.411000	1.01e-02
REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY	25	1.94e-03	0.358000	1.02e-02
REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	30	1.94e-03	-0.327000	1.02e-02
REACTOME PHOSPHOLIPID METABOLISM	201	1.99e-03	0.126000	1.04e-02
REACTOME EXTENSION OF TELOMERES	49	2.10e-03	0.254000	1.10e-02
REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	48	2.19e-03	0.256000	1.14e-02
REACTOME RNA POLYMERASE I TRANSCRIPTION TERMINATION	30	2.19e-03	0.323000	1.14e-02
REACTOME CGMP EFFECTS	16	2.21e-03	-0.442000	1.15e-02
REACTOME PKMTS METHYLATE HISTONE LYSINES	64	2.22e-03	0.221000	1.15e-02
REACTOME RUNX3 REGULATES NOTCH SIGNALING	13	2.25e-03	0.489000	1.16e-02
REACTOME LATE ENDOSOMAL MICROAUTOPHAGY	33	2.25e-03	0.307000	1.16e-02
REACTOME LAGGING STRAND SYNTHESIS	19	2.34e-03	0.403000	1.20e-02
REACTOME GLUCOCORTICOID BIOSYNTHESIS	10	2.35e-03	-0.555000	1.20e-02
REACTOME ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE	9	2.35e-03	-0.585000	1.20e-02
REACTOME MEIOSIS	110	2.37e-03	0.168000	1.20e-02
REACTOME OXIDATIVE STRESS INDUCED SENESCENCE	118	2.49e-03	0.161000	1.26e-02
REACTOME ACTIVATION OF MATRIX METALLOPROTEINASES	30	2.57e-03	-0.318000	1.29e-02
REACTOME BUDDING AND MATURATION OF HIV VIRION	28	2.58e-03	0.329000	1.30e-02
REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	23	2.63e-03	-0.362000	1.32e-02
REACTOME FANCONI ANEMIA PATHWAY	35	2.65e-03	0.293000	1.32e-02
REACTOME BASE EXCISION REPAIR AP SITE FORMATION	59	2.67e-03	0.226000	1.33e-02
REACTOME AMINO ACIDS REGULATE MTORC1	53	2.71e-03	0.238000	1.34e-02
REACTOME COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES	65	2.86e-03	-0.214000	1.41e-02
REACTOME GLUCOSE METABOLISM	90	2.88e-03	0.182000	1.42e-02
REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS	113	2.92e-03	0.162000	1.44e-02
REACTOME MEIOTIC SYNAPSIS	73	2.96e-03	0.201000	1.45e-02
REACTOME SIGNALING BY VEGF	102	3.02e-03	0.170000	1.48e-02
REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	31	3.05e-03	0.307000	1.48e-02
REACTOME ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT	23	3.05e-03	0.357000	1.48e-02
REACTOME COSTIMULATION BY THE CD28 FAMILY	64	3.17e-03	0.213000	1.54e-02
REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS	27	3.20e-03	0.328000	1.55e-02
REACTOME REGULATION OF PTEN GENE TRANSCRIPTION	59	3.21e-03	0.222000	1.55e-02
REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP	41	3.24e-03	0.266000	1.56e-02
REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	20	3.25e-03	0.380000	1.56e-02
REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS	83	3.30e-03	0.187000	1.57e-02
REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	14	3.31e-03	0.453000	1.58e-02
REACTOME SIGNALING BY ALK IN CANCER	53	3.34e-03	0.233000	1.58e-02
REACTOME DNA DAMAGE RECOGNITION IN GG NER	36	3.34e-03	0.283000	1.58e-02
REACTOME MYD88 INDEPENDENT TLR4 CASCADE	103	3.35e-03	0.167000	1.58e-02
REACTOME CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER	25	3.37e-03	0.339000	1.59e-02
REACTOME FATTY ACIDS	15	3.43e-03	-0.436000	1.61e-02
REACTOME PYRUVATE METABOLISM	29	3.46e-03	0.314000	1.62e-02
REACTOME CALNEXIN CALRETICULIN CYCLE	26	3.53e-03	0.331000	1.65e-02
REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	91	3.57e-03	0.177000	1.66e-02
REACTOME THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT	77	3.73e-03	0.191000	1.73e-02
REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION	60	3.75e-03	0.216000	1.73e-02
REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	66	3.84e-03	0.206000	1.77e-02
REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE	19	3.86e-03	0.383000	1.78e-02
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	28	4.06e-03	0.314000	1.86e-02
REACTOME ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY	10	4.12e-03	0.524000	1.89e-02
REACTOME NEUROTRANSMITTER RELEASE CYCLE	48	4.19e-03	-0.239000	1.91e-02
REACTOME COPII MEDIATED VESICLE TRANSPORT	66	4.22e-03	0.204000	1.92e-02
REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	49	4.25e-03	0.236000	1.93e-02
REACTOME ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS	41	4.28e-03	-0.258000	1.93e-02
REACTOME LGI ADAM INTERACTIONS	14	4.31e-03	-0.441000	1.94e-02
REACTOME DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM	38	4.40e-03	-0.267000	1.98e-02
REACTOME MITOCHONDRIAL CALCIUM ION TRANSPORT	23	4.43e-03	0.343000	1.99e-02
REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	19	4.50e-03	0.376000	2.01e-02
REACTOME DNA DAMAGE BYPASS	47	4.53e-03	0.239000	2.02e-02
REACTOME DISORDERS OF TRANSMEMBRANE TRANSPORTERS	170	4.81e-03	0.125000	2.14e-02
REACTOME POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE	25	4.84e-03	0.325000	2.15e-02
REACTOME RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX	29	4.87e-03	0.302000	2.16e-02
REACTOME G PROTEIN BETA GAMMA SIGNALLING	30	4.90e-03	0.297000	2.16e-02
REACTOME PHASE 4 RESTING MEMBRANE POTENTIAL	19	4.91e-03	-0.373000	2.16e-02
REACTOME SIGNALING BY INTERLEUKINS	444	4.92e-03	0.077800	2.16e-02
REACTOME TRANSCRIPTIONAL REGULATION BY VENTX	41	4.96e-03	0.254000	2.17e-02
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS	161	5.33e-03	0.127000	2.33e-02
REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	15	5.38e-03	-0.415000	2.34e-02
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	53	5.71e-03	0.219000	2.48e-02
REACTOME PROCESSING OF INTRONLESS PRE MRNAS	19	6.04e-03	0.364000	2.61e-02
REACTOME HDR THROUGH HOMOLOGOUS RECOMBINATION HRR	66	6.06e-03	0.195000	2.61e-02
REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	91	6.08e-03	-0.166000	2.61e-02
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX2	117	6.08e-03	0.147000	2.61e-02
REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	93	6.11e-03	-0.164000	2.62e-02
REACTOME NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION	193	6.19e-03	-0.114000	2.65e-02
REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS	18	6.23e-03	0.372000	2.66e-02
REACTOME GOLGI TO ER RETROGRADE TRANSPORT	132	6.44e-03	0.137000	2.74e-02
REACTOME PI METABOLISM	79	6.47e-03	0.177000	2.75e-02
REACTOME MET ACTIVATES PTK2 SIGNALING	30	6.58e-03	-0.287000	2.77e-02
REACTOME PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR	21	6.58e-03	0.343000	2.77e-02
REACTOME CONDENSATION OF PROPHASE CHROMOSOMES	66	6.59e-03	0.193000	2.77e-02
REACTOME PERK REGULATES GENE EXPRESSION	31	6.67e-03	0.282000	2.80e-02
REACTOME PROCESSING AND ACTIVATION OF SUMO	10	6.70e-03	0.495000	2.81e-02
REACTOME DIGESTION OF DIETARY LIPID	7	6.85e-03	-0.590000	2.86e-02
REACTOME EXTRA NUCLEAR ESTROGEN SIGNALING	74	6.89e-03	0.182000	2.87e-02
REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION	62	7.23e-03	0.197000	3.01e-02
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES	49	7.31e-03	0.221000	3.03e-02
REACTOME REGULATION OF TP53 EXPRESSION AND DEGRADATION	37	7.32e-03	0.255000	3.03e-02
REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN	37	7.48e-03	0.254000	3.08e-02
REACTOME CELLULAR RESPONSE TO STARVATION	147	7.58e-03	0.128000	3.12e-02
REACTOME DISEASES OF DNA REPAIR	51	7.60e-03	0.216000	3.12e-02
REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	12	7.69e-03	-0.444000	3.15e-02
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX	91	7.82e-03	0.161000	3.19e-02
REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	11	7.88e-03	-0.463000	3.21e-02
REACTOME GPVI MEDIATED ACTIVATION CASCADE	35	8.05e-03	0.259000	3.27e-02
REACTOME PROTEIN FOLDING	96	8.17e-03	0.156000	3.31e-02
REACTOME CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE	49	8.22e-03	0.218000	3.32e-02
REACTOME ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS	20	8.27e-03	0.341000	3.34e-02
REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	22	8.31e-03	0.325000	3.34e-02
REACTOME RNA POLYMERASE III CHAIN ELONGATION	18	8.36e-03	0.359000	3.36e-02
REACTOME DEFECTIVE CHST14 CAUSES EDS MUSCULOCONTRACTURAL TYPE	7	8.53e-03	-0.574000	3.41e-02
REACTOME TRIGLYCERIDE BIOSYNTHESIS	12	8.54e-03	-0.438000	3.41e-02
REACTOME INTERFERON SIGNALING	193	8.66e-03	0.110000	3.45e-02
REACTOME DEFECTIVE CHST3 CAUSES SEDCJD	7	8.75e-03	-0.572000	3.48e-02
REACTOME HORMONE LIGAND BINDING RECEPTORS	12	8.80e-03	-0.437000	3.49e-02
REACTOME DERMATAN SULFATE BIOSYNTHESIS	10	8.89e-03	-0.478000	3.51e-02
REACTOME REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO	10	8.90e-03	-0.478000	3.51e-02
REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA	28	8.98e-03	0.285000	3.53e-02
REACTOME SIGNALING BY TGFB FAMILY MEMBERS	119	9.03e-03	0.139000	3.55e-02
REACTOME MISMATCH REPAIR	15	9.12e-03	0.389000	3.57e-02
REACTOME BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA	5	9.23e-03	0.672000	3.61e-02
REACTOME CYTOSOLIC TRNA AMINOACYLATION	22	9.36e-03	0.320000	3.65e-02
REACTOME SARS COV 2 ACTIVATES MODULATES INNATE AND ADAPTIVE IMMUNE RESPONSES	118	9.48e-03	0.138000	3.69e-02
REACTOME COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING	38	9.59e-03	0.243000	3.72e-02
REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	29	9.70e-03	0.277000	3.76e-02
REACTOME TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS	52	9.72e-03	0.207000	3.76e-02
REACTOME SENSORY PROCESSING OF SOUND	72	9.82e-03	-0.176000	3.79e-02
REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	17	9.92e-03	-0.361000	3.81e-02
REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE	52	1.02e-02	0.206000	3.93e-02
REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX	39	1.03e-02	0.237000	3.94e-02
REACTOME RHOU GTPASE CYCLE	37	1.04e-02	0.243000	3.99e-02
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	122	1.06e-02	-0.134000	4.04e-02
REACTOME COLLAGEN FORMATION	88	1.07e-02	-0.157000	4.06e-02
REACTOME PROCESSING OF SMDT1	16	1.08e-02	0.368000	4.10e-02
REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	52	1.09e-02	0.204000	4.13e-02
REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	11	1.11e-02	0.442000	4.19e-02
REACTOME HEME SIGNALING	47	1.11e-02	0.214000	4.19e-02
REACTOME BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA	6	1.11e-02	0.598000	4.19e-02
REACTOME NONHOMOLOGOUS END JOINING NHEJ	64	1.12e-02	0.183000	4.19e-02
REACTOME FGFR1C LIGAND BINDING AND ACTIVATION	11	1.15e-02	-0.440000	4.31e-02
REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	21	1.16e-02	0.318000	4.33e-02
REACTOME HS GAG BIOSYNTHESIS	28	1.16e-02	-0.275000	4.33e-02
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12	22	1.17e-02	0.310000	4.36e-02
REACTOME DNA DOUBLE STRAND BREAK RESPONSE	74	1.18e-02	0.169000	4.37e-02
REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	38	1.18e-02	0.236000	4.38e-02
REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION	74	1.20e-02	0.169000	4.41e-02
REACTOME SARS COV 2 MODULATES AUTOPHAGY	11	1.23e-02	0.436000	4.51e-02
REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX	36	1.23e-02	0.241000	4.51e-02
REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS	28	1.24e-02	0.273000	4.53e-02
REACTOME ASSEMBLY OF THE HIV VIRION	16	1.25e-02	0.361000	4.57e-02
REACTOME ERBB2 ACTIVATES PTK6 SIGNALING	13	1.26e-02	-0.400000	4.58e-02
REACTOME L1CAM INTERACTIONS	112	1.31e-02	-0.136000	4.76e-02
REACTOME INTERLEUKIN 2 SIGNALING	11	1.31e-02	0.432000	4.76e-02
REACTOME FLT3 SIGNALING	38	1.32e-02	0.232000	4.78e-02
REACTOME PI5P REGULATES TP53 ACETYLATION	9	1.33e-02	0.477000	4.80e-02
REACTOME NR1H2 AND NR1H3 MEDIATED SIGNALING	46	1.33e-02	0.211000	4.81e-02
REACTOME RNA POLYMERASE III TRANSCRIPTION TERMINATION	23	1.34e-02	0.298000	4.81e-02
REACTOME PHOSPHORYLATION OF THE APC C	20	1.34e-02	0.319000	4.83e-02
REACTOME TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE	20	1.35e-02	-0.319000	4.85e-02
REACTOME RORA ACTIVATES GENE EXPRESSION	17	1.36e-02	0.346000	4.87e-02
REACTOME G ALPHA I SIGNALLING EVENTS	304	1.39e-02	-0.082000	4.97e-02
REACTOME TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN	21	1.40e-02	0.310000	4.98e-02
REACTOME CARNITINE METABOLISM	13	1.40e-02	0.393000	4.98e-02
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES	15	1.40e-02	0.366000	4.98e-02
REACTOME RHO GTPASES ACTIVATE WASPS AND WAVES	34	1.41e-02	0.243000	5.00e-02
REACTOME SARS COV 1 INFECTION	136	1.45e-02	0.121000	5.12e-02
REACTOME METALLOPROTEASE DUBS	36	1.45e-02	0.235000	5.12e-02
REACTOME EUKARYOTIC TRANSLATION INITIATION	110	1.48e-02	0.135000	5.19e-02
REACTOME NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10	12	1.48e-02	0.406000	5.19e-02
REACTOME NUCLEAR ENVELOPE NE REASSEMBLY	74	1.49e-02	0.164000	5.22e-02
REACTOME METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES	33	1.51e-02	-0.245000	5.25e-02
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST	18	1.51e-02	0.331000	5.25e-02
REACTOME MATURATION OF PROTEIN 3A	9	1.52e-02	0.467000	5.28e-02
REACTOME ATTACHMENT AND ENTRY	16	1.53e-02	-0.350000	5.32e-02
REACTOME MELANIN BIOSYNTHESIS	5	1.54e-02	-0.625000	5.35e-02
REACTOME REGULATION OF MECP2 EXPRESSION AND ACTIVITY	30	1.55e-02	0.255000	5.36e-02
REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	26	1.56e-02	0.274000	5.38e-02
REACTOME REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM	11	1.56e-02	0.421000	5.38e-02
REACTOME SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER	54	1.58e-02	0.190000	5.43e-02
REACTOME MTOR SIGNALLING	40	1.59e-02	0.220000	5.45e-02
REACTOME DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE	30	1.60e-02	0.254000	5.46e-02
REACTOME GAP JUNCTION ASSEMBLY	36	1.60e-02	-0.232000	5.46e-02
REACTOME TOLL LIKE RECEPTOR CASCADES	158	1.60e-02	0.111000	5.46e-02
REACTOME RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY	14	1.62e-02	0.371000	5.49e-02
REACTOME BIOSYNTHESIS OF MARESINS	8	1.62e-02	-0.491000	5.49e-02
REACTOME ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES	59	1.62e-02	-0.181000	5.49e-02
REACTOME FOLDING OF ACTIN BY CCT TRIC	10	1.63e-02	0.438000	5.52e-02
REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	18	1.64e-02	-0.327000	5.53e-02
REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET	8	1.65e-02	-0.489000	5.56e-02
REACTOME METABOLISM OF CARBOHYDRATES	279	1.68e-02	0.083200	5.65e-02
REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3	59	1.70e-02	0.180000	5.70e-02
REACTOME DISEASES OF METABOLISM	237	1.70e-02	-0.090000	5.70e-02
REACTOME NEUROFASCIN INTERACTIONS	6	1.72e-02	-0.562000	5.73e-02
REACTOME ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS	27	1.72e-02	0.265000	5.73e-02
REACTOME DOPAMINE RECEPTORS	5	1.74e-02	-0.614000	5.78e-02
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION	250	1.74e-02	0.087300	5.78e-02
REACTOME MAPK FAMILY SIGNALING CASCADES	314	1.75e-02	0.078000	5.79e-02
REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION	8	1.76e-02	-0.485000	5.82e-02
REACTOME PREDNISONE ADME	10	1.78e-02	-0.433000	5.85e-02
REACTOME CELL CELL COMMUNICATION	126	1.78e-02	-0.122000	5.86e-02
REACTOME DUAL INCISION IN GG NER	39	1.78e-02	0.219000	5.86e-02
REACTOME G BETA GAMMA SIGNALLING THROUGH CDC42	19	1.79e-02	0.314000	5.87e-02
REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	20	1.83e-02	0.305000	5.98e-02
REACTOME GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER	25	1.89e-02	0.271000	6.19e-02
REACTOME GPER1 SIGNALING	45	1.90e-02	0.202000	6.20e-02
REACTOME UBIQUINOL BIOSYNTHESIS	8	1.93e-02	0.478000	6.26e-02
REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM	23	1.93e-02	0.282000	6.27e-02
REACTOME DISEASES OF GLYCOSYLATION	137	1.94e-02	-0.116000	6.27e-02
REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS	6	1.98e-02	-0.549000	6.39e-02
REACTOME INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE	20	1.99e-02	0.301000	6.41e-02
REACTOME RHO GTPASES ACTIVATE PAKS	19	1.99e-02	0.309000	6.41e-02
REACTOME TRANSCRIPTIONAL REGULATION BY E2F6	32	2.00e-02	0.238000	6.42e-02
REACTOME FGFR2 LIGAND BINDING AND ACTIVATION	19	2.01e-02	-0.308000	6.46e-02
REACTOME METABOLISM OF FAT SOLUBLE VITAMINS	46	2.04e-02	-0.198000	6.53e-02
REACTOME SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA	52	2.05e-02	-0.186000	6.54e-02
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD4	15	2.05e-02	0.345000	6.54e-02
REACTOME MEIOTIC RECOMBINATION	80	2.08e-02	0.150000	6.61e-02
REACTOME NEF MEDIATED CD8 DOWN REGULATION	7	2.11e-02	0.503000	6.69e-02
REACTOME MUCOPOLYSACCHARIDOSES	10	2.12e-02	0.421000	6.71e-02
REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	44	2.13e-02	0.201000	6.74e-02
REACTOME RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK	47	2.18e-02	0.193000	6.89e-02
REACTOME ENDOSOMAL VACUOLAR PATHWAY	11	2.24e-02	-0.398000	7.06e-02
REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION	42	2.26e-02	0.203000	7.10e-02
REACTOME GLYCOGEN METABOLISM	22	2.29e-02	0.280000	7.18e-02
REACTOME NEF AND SIGNAL TRANSDUCTION	8	2.29e-02	0.464000	7.18e-02
REACTOME CA2 ACTIVATED K CHANNELS	9	2.31e-02	-0.437000	7.20e-02
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY DVL INTERACTING PROTEINS	5	2.31e-02	0.587000	7.20e-02
REACTOME FGFR3 LIGAND BINDING AND ACTIVATION	12	2.31e-02	-0.379000	7.20e-02
REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	24	2.31e-02	0.268000	7.20e-02
REACTOME NUCLEOTIDE BIOSYNTHESIS	14	2.36e-02	0.349000	7.34e-02
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	36	2.39e-02	0.218000	7.39e-02
REACTOME COPI MEDIATED ANTEROGRADE TRANSPORT	101	2.39e-02	0.130000	7.39e-02
REACTOME WNT MEDIATED ACTIVATION OF DVL	8	2.39e-02	0.461000	7.39e-02
REACTOME SCAVENGING OF HEME FROM PLASMA	13	2.44e-02	-0.361000	7.50e-02
REACTOME TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE	39	2.44e-02	0.208000	7.50e-02
REACTOME PROTEIN METHYLATION	17	2.45e-02	0.315000	7.53e-02
REACTOME PHASE 1 INACTIVATION OF FAST NA CHANNELS	6	2.47e-02	-0.530000	7.56e-02
REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	19	2.55e-02	-0.296000	7.79e-02
REACTOME SIGNALING BY NTRKS	132	2.61e-02	0.112000	7.96e-02
REACTOME REGULATION OF TP53 ACTIVITY THROUGH METHYLATION	19	2.62e-02	0.295000	7.97e-02
REACTOME REGULATION OF SIGNALING BY NODAL	9	2.64e-02	0.428000	8.01e-02
REACTOME NEF MEDIATED CD4 DOWN REGULATION	9	2.66e-02	0.427000	8.05e-02
REACTOME RIP MEDIATED NFKB ACTIVATION VIA ZBP1	16	2.66e-02	0.320000	8.05e-02
REACTOME TRIF MEDIATED PROGRAMMED CELL DEATH	9	2.66e-02	0.427000	8.05e-02
REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT	236	2.68e-02	-0.083700	8.08e-02
REACTOME RHO GTPASES ACTIVATE CIT	19	2.68e-02	0.293000	8.08e-02
REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	24	2.69e-02	0.261000	8.08e-02
REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	37	2.69e-02	0.210000	8.08e-02
REACTOME POLB DEPENDENT LONG PATCH BASE EXCISION REPAIR	8	2.70e-02	0.452000	8.08e-02
REACTOME PECAM1 INTERACTIONS	12	2.70e-02	0.369000	8.08e-02
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS	6	2.71e-02	0.521000	8.09e-02
REACTOME UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION	19	2.72e-02	-0.293000	8.09e-02
REACTOME SUMO IS TRANSFERRED FROM E1 TO E2 UBE2I UBC9	7	2.73e-02	0.482000	8.13e-02
REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	15	2.76e-02	0.329000	8.18e-02
REACTOME REPRESSION OF WNT TARGET GENES	14	2.76e-02	0.340000	8.18e-02
REACTOME DEATH RECEPTOR SIGNALING	143	2.79e-02	0.107000	8.24e-02
REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE	109	2.80e-02	0.122000	8.27e-02
REACTOME REGULATION OF NF KAPPA B SIGNALING	17	2.81e-02	0.308000	8.29e-02
REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES	7	2.82e-02	0.479000	8.31e-02
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX	19	2.84e-02	0.290000	8.34e-02
REACTOME INTERLEUKIN 2 FAMILY SIGNALING	40	2.85e-02	0.200000	8.37e-02
REACTOME VLDLR INTERNALISATION AND DEGRADATION	16	2.87e-02	0.316000	8.40e-02
REACTOME REGULATION OF KIT SIGNALING	16	3.00e-02	0.313000	8.76e-02
REACTOME POLYMERASE SWITCHING	13	3.01e-02	0.347000	8.77e-02
REACTOME LYSOSOME VESICLE BIOGENESIS	33	3.01e-02	0.218000	8.77e-02
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS	15	3.02e-02	-0.323000	8.77e-02
REACTOME RELEASE OF HH NP FROM THE SECRETING CELL	8	3.03e-02	-0.442000	8.77e-02
REACTOME MISCELLANEOUS SUBSTRATES	12	3.03e-02	-0.361000	8.77e-02
REACTOME METABOLISM OF COFACTORS	19	3.03e-02	0.287000	8.77e-02
REACTOME RECYCLING OF EIF2 GDP	7	3.06e-02	0.472000	8.82e-02
REACTOME HEME BIOSYNTHESIS	13	3.10e-02	0.345000	8.93e-02
REACTOME ER QUALITY CONTROL COMPARTMENT ERQC	21	3.10e-02	0.272000	8.93e-02
REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	14	3.12e-02	0.333000	8.96e-02
REACTOME CELLULAR HEXOSE TRANSPORT	21	3.13e-02	-0.271000	8.96e-02
REACTOME CD209 DC SIGN SIGNALING	20	3.14e-02	0.278000	8.99e-02
REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	14	3.17e-02	0.332000	9.03e-02
REACTOME ATTENUATION PHASE	27	3.17e-02	0.239000	9.03e-02
REACTOME RHOC GTPASE CYCLE	71	3.21e-02	0.147000	9.13e-02
REACTOME HDR THROUGH SINGLE STRAND ANNEALING SSA	37	3.22e-02	0.204000	9.14e-02
REACTOME TNF SIGNALING	54	3.27e-02	0.168000	9.27e-02
REACTOME PRC2 METHYLATES HISTONES AND DNA	65	3.31e-02	0.153000	9.38e-02
REACTOME DNA METHYLATION	58	3.32e-02	0.162000	9.38e-02
REACTOME MATURATION OF SARS COV 1 SPIKE PROTEIN	5	3.32e-02	0.550000	9.38e-02
REACTOME SIGNALING BY NODAL	20	3.34e-02	0.275000	9.41e-02
REACTOME PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING	11	3.35e-02	-0.370000	9.41e-02
REACTOME TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY	30	3.47e-02	0.223000	9.75e-02
REACTOME ANCHORING FIBRIL FORMATION	13	3.50e-02	-0.338000	9.80e-02
REACTOME SIGNALING BY NOTCH3	48	3.51e-02	0.176000	9.80e-02
REACTOME DEFECTIVE EXT2 CAUSES EXOSTOSES 2	12	3.57e-02	-0.350000	9.98e-02
REACTOME LONG TERM POTENTIATION	22	3.61e-02	-0.258000	1.01e-01
REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	67	3.61e-02	0.148000	1.01e-01
REACTOME HUR ELAVL1 BINDS AND STABILIZES MRNA	8	3.64e-02	0.427000	1.01e-01
REACTOME GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	34	3.66e-02	0.207000	1.02e-01
REACTOME RND2 GTPASE CYCLE	42	3.68e-02	0.186000	1.02e-01
REACTOME ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS	24	3.71e-02	0.246000	1.02e-01
REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE	9	3.72e-02	-0.401000	1.02e-01
REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	31	3.72e-02	0.216000	1.02e-01
REACTOME RAC2 GTPASE CYCLE	81	3.73e-02	0.134000	1.02e-01
REACTOME HSF1 ACTIVATION	29	3.73e-02	0.223000	1.02e-01
REACTOME SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL	8	3.75e-02	0.425000	1.03e-01
REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	12	3.75e-02	-0.347000	1.03e-01
REACTOME CTLA4 INHIBITORY SIGNALING	21	3.75e-02	0.262000	1.03e-01
REACTOME MAPK1 ERK2 ACTIVATION	9	3.77e-02	0.400000	1.03e-01
REACTOME TERMINATION OF TRANSLESION DNA SYNTHESIS	32	3.78e-02	0.212000	1.03e-01
REACTOME APEX1 INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	7	3.83e-02	0.452000	1.04e-01
REACTOME SMALL INTERFERING RNA SIRNA BIOGENESIS	9	3.87e-02	0.398000	1.05e-01
REACTOME NETRIN 1 SIGNALING	49	3.93e-02	-0.170000	1.06e-01
REACTOME MET RECEPTOR ACTIVATION	6	3.96e-02	-0.485000	1.07e-01
REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS	29	3.97e-02	-0.221000	1.07e-01
REACTOME SPRY REGULATION OF FGF SIGNALING	16	3.98e-02	0.297000	1.07e-01
REACTOME SARS COV 2 TARGETS PDZ PROTEINS IN CELL CELL JUNCTION	5	3.99e-02	-0.531000	1.07e-01
REACTOME BETA CATENIN PHOSPHORYLATION CASCADE	16	4.01e-02	0.296000	1.08e-01
REACTOME MHC CLASS II ANTIGEN PRESENTATION	121	4.04e-02	0.108000	1.08e-01
REACTOME LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME	11	4.06e-02	0.357000	1.09e-01
REACTOME CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT	19	4.10e-02	0.271000	1.09e-01
REACTOME FGFR2 ALTERNATIVE SPLICING	27	4.11e-02	0.227000	1.09e-01
REACTOME SEROTONIN RECEPTORS	11	4.12e-02	-0.356000	1.09e-01
REACTOME REGULATION OF NPAS4 MRNA TRANSLATION	9	4.12e-02	0.393000	1.09e-01
REACTOME HEMOSTASIS	591	4.13e-02	0.049100	1.09e-01
REACTOME G1 S SPECIFIC TRANSCRIPTION	28	4.13e-02	0.223000	1.09e-01
REACTOME SIGNAL AMPLIFICATION	33	4.13e-02	0.205000	1.09e-01
REACTOME SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS	14	4.15e-02	0.315000	1.10e-01
REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	39	4.21e-02	-0.188000	1.11e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES	33	4.23e-02	0.204000	1.12e-01
REACTOME LRR FLII INTERACTING PROTEIN 1 LRRFIP1 ACTIVATES TYPE I IFN PRODUCTION	5	4.32e-02	0.522000	1.14e-01
REACTOME FGFR3B LIGAND BINDING AND ACTIVATION	7	4.35e-02	-0.441000	1.14e-01
REACTOME RETINOID CYCLE DISEASE EVENTS	11	4.35e-02	-0.352000	1.14e-01
REACTOME FCERI MEDIATED CA 2 MOBILIZATION	30	4.35e-02	0.213000	1.14e-01
REACTOME HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE	43	4.36e-02	0.178000	1.14e-01
REACTOME SIGNALING BY NOTCH1	69	4.37e-02	0.140000	1.14e-01
REACTOME ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN	13	4.38e-02	-0.323000	1.14e-01
REACTOME MATURATION OF SARS COV 2 NUCLEOPROTEIN	15	4.39e-02	0.301000	1.14e-01
REACTOME PI 3K CASCADE FGFR1	21	4.40e-02	-0.254000	1.14e-01
REACTOME REGULATION OF SIGNALING BY CBL	22	4.42e-02	0.248000	1.14e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K	12	4.42e-02	0.335000	1.14e-01
REACTOME POST TRANSCRIPTIONAL SILENCING BY SMALL RNAS	7	4.42e-02	0.439000	1.14e-01
REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION	20	4.45e-02	0.260000	1.15e-01
REACTOME FCGR ACTIVATION	11	4.49e-02	0.349000	1.16e-01
REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	45	4.53e-02	-0.172000	1.16e-01
REACTOME PI3K EVENTS IN ERBB4 SIGNALING	10	4.54e-02	-0.365000	1.16e-01
REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM	50	4.55e-02	-0.164000	1.16e-01
REACTOME ABACAVIR ADME	9	4.55e-02	-0.385000	1.16e-01
REACTOME GLUCURONIDATION	23	4.55e-02	-0.241000	1.16e-01
REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	11	4.57e-02	-0.348000	1.17e-01
REACTOME PROTON COUPLED MONOCARBOXYLATE TRANSPORT	6	4.59e-02	0.471000	1.17e-01
REACTOME ACYL CHAIN REMODELLING OF PI	17	4.59e-02	-0.280000	1.17e-01
REACTOME DEFECTIVE GALNT3 CAUSES HFTC	16	4.63e-02	-0.288000	1.18e-01
REACTOME FOXO MEDIATED TRANSCRIPTION	65	4.63e-02	0.143000	1.18e-01
REACTOME DISEASES OF MITOTIC CELL CYCLE	37	4.64e-02	0.189000	1.18e-01
REACTOME NOD1 2 SIGNALING PATHWAY	33	4.65e-02	0.200000	1.18e-01
REACTOME BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA	17	4.68e-02	0.279000	1.18e-01
REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	62	4.68e-02	0.146000	1.18e-01
REACTOME G ALPHA S SIGNALLING EVENTS	155	4.70e-02	-0.092400	1.18e-01
REACTOME METABOLISM OF STEROID HORMONES	35	4.72e-02	-0.194000	1.19e-01
REACTOME STIMULI SENSING CHANNELS	100	4.72e-02	-0.115000	1.19e-01
REACTOME DISEASES OF BASE EXCISION REPAIR	5	4.76e-02	0.511000	1.19e-01
REACTOME ERKS ARE INACTIVATED	13	4.79e-02	0.317000	1.20e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES	11	4.83e-02	0.344000	1.21e-01
REACTOME FERTILIZATION	26	4.84e-02	-0.224000	1.21e-01
REACTOME G ALPHA Q SIGNALLING EVENTS	206	4.88e-02	-0.079600	1.22e-01
REACTOME RAC1 GTPASE CYCLE	172	4.92e-02	0.086900	1.22e-01
REACTOME NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY	6	4.95e-02	0.463000	1.23e-01
REACTOME FORMATION OF INCISION COMPLEX IN GG NER	40	4.95e-02	0.179000	1.23e-01
REACTOME NONSENSE MEDIATED DECAY NMD	107	5.01e-02	0.110000	1.24e-01
REACTOME NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	24	5.06e-02	0.231000	1.25e-01
REACTOME CRISTAE FORMATION	27	5.09e-02	0.217000	1.26e-01
REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	53	5.14e-02	0.155000	1.27e-01
REACTOME RRNA PROCESSING IN THE MITOCHONDRION	9	5.17e-02	0.374000	1.27e-01
REACTOME TELOMERE C STRAND SYNTHESIS INITIATION	12	5.18e-02	0.324000	1.27e-01
REACTOME RAS PROCESSING	22	5.19e-02	0.239000	1.27e-01
REACTOME BASIGIN INTERACTIONS	24	5.32e-02	0.228000	1.30e-01
REACTOME RHO GTPASES ACTIVATE KTN1	11	5.33e-02	0.337000	1.30e-01
REACTOME LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX	5	5.35e-02	0.499000	1.31e-01
REACTOME PEPTIDE HORMONE METABOLISM	84	5.42e-02	-0.121000	1.32e-01
REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	21	5.49e-02	-0.242000	1.34e-01
REACTOME REGULATION OF PTEN MRNA TRANSLATION	9	5.51e-02	0.369000	1.34e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR4	14	5.53e-02	-0.296000	1.34e-01
REACTOME MITOPHAGY	28	5.57e-02	0.209000	1.35e-01
REACTOME DEFECTIVE RIPK1 MEDIATED REGULATED NECROSIS	7	5.57e-02	0.418000	1.35e-01
REACTOME RHOD GTPASE CYCLE	49	5.58e-02	0.158000	1.35e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2	17	5.59e-02	-0.268000	1.35e-01
REACTOME COMPLEMENT CASCADE	54	5.67e-02	-0.150000	1.37e-01
REACTOME PARACETAMOL ADME	26	5.69e-02	-0.216000	1.37e-01
REACTOME CLATHRIN MEDIATED ENDOCYTOSIS	139	5.71e-02	0.093500	1.37e-01
REACTOME REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS	15	5.78e-02	0.283000	1.38e-01
REACTOME ENDOGENOUS STEROLS	26	5.78e-02	-0.215000	1.38e-01
REACTOME DEFECTIVE CHSY1 CAUSES TPBS	7	5.79e-02	-0.414000	1.38e-01
REACTOME CREATION OF C4 AND C2 ACTIVATORS	14	5.80e-02	-0.293000	1.39e-01
REACTOME ARACHIDONATE PRODUCTION FROM DAG	5	5.90e-02	0.488000	1.41e-01
REACTOME PIWI INTERACTING RNA PIRNA BIOGENESIS	29	5.93e-02	0.202000	1.41e-01
REACTOME NEGATIVE REGULATION OF MAPK PATHWAY	41	5.97e-02	0.170000	1.42e-01
REACTOME TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA	17	6.02e-02	0.263000	1.43e-01
REACTOME SEROTONIN NEUROTRANSMITTER RELEASE CYCLE	17	6.03e-02	-0.263000	1.43e-01
REACTOME INTEGRIN SIGNALING	27	6.06e-02	0.209000	1.44e-01
REACTOME TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX	14	6.13e-02	0.289000	1.45e-01
REACTOME SARS COV 2 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS	12	6.14e-02	0.312000	1.45e-01
REACTOME REPRODUCTION	136	6.14e-02	0.092900	1.45e-01
REACTOME METABOLISM OF AMINE DERIVED HORMONES	17	6.16e-02	-0.262000	1.45e-01
REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION	11	6.17e-02	-0.325000	1.45e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS	9	6.17e-02	0.360000	1.45e-01
REACTOME EICOSANOIDS	12	6.18e-02	-0.311000	1.45e-01
REACTOME FGFRL1 MODULATION OF FGFR1 SIGNALING	13	6.23e-02	-0.299000	1.46e-01
REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	36	6.23e-02	0.180000	1.46e-01
REACTOME GLYCOSPHINGOLIPID METABOLISM	39	6.23e-02	0.172000	1.46e-01
REACTOME HSF1 DEPENDENT TRANSACTIVATION	37	6.26e-02	0.177000	1.46e-01
REACTOME TRIGLYCERIDE CATABOLISM	23	6.28e-02	0.224000	1.46e-01
REACTOME FRS MEDIATED FGFR1 SIGNALING	23	6.40e-02	-0.223000	1.49e-01
REACTOME ALPHA DEFENSINS	6	6.40e-02	-0.437000	1.49e-01
REACTOME TAK1 DEPENDENT IKK AND NF KAPPA B ACTIVATION	41	6.43e-02	0.167000	1.49e-01
REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	26	6.47e-02	0.209000	1.50e-01
REACTOME ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION	16	6.50e-02	0.266000	1.50e-01
REACTOME RHOJ GTPASE CYCLE	51	6.55e-02	0.149000	1.51e-01
REACTOME FGFR1B LIGAND BINDING AND ACTIVATION	6	6.56e-02	-0.434000	1.51e-01
REACTOME SIGNALING BY KIT IN DISEASE	20	6.66e-02	0.237000	1.53e-01
REACTOME TIGHT JUNCTION INTERACTIONS	29	6.69e-02	-0.197000	1.54e-01
REACTOME MINERALOCORTICOID BIOSYNTHESIS	6	6.76e-02	-0.431000	1.55e-01
REACTOME TRANSLESION SYNTHESIS BY POLH	19	6.77e-02	0.242000	1.55e-01
REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND	21	6.80e-02	-0.230000	1.56e-01
REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	29	6.81e-02	0.196000	1.56e-01
REACTOME INTERLEUKIN 18 SIGNALING	8	6.85e-02	0.372000	1.56e-01
REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	123	6.86e-02	0.095100	1.56e-01
REACTOME TACHYKININ RECEPTORS BIND TACHYKININS	5	6.86e-02	-0.470000	1.56e-01
REACTOME MUSCARINIC ACETYLCHOLINE RECEPTORS	5	7.00e-02	-0.468000	1.59e-01
REACTOME RHOBTB GTPASE CYCLE	34	7.00e-02	0.180000	1.59e-01
REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING	6	7.03e-02	-0.427000	1.59e-01
REACTOME O LINKED GLYCOSYLATION	109	7.04e-02	-0.100000	1.59e-01
REACTOME SIGNALING BY LRP5 MUTANTS	6	7.05e-02	-0.426000	1.60e-01
REACTOME PENTOSE PHOSPHATE PATHWAY	12	7.08e-02	0.301000	1.60e-01
REACTOME CDC42 GTPASE CYCLE	144	7.09e-02	0.087200	1.60e-01
REACTOME SIGNALING BY CSF3 G CSF	30	7.11e-02	0.190000	1.60e-01
REACTOME SHC MEDIATED CASCADE FGFR1	21	7.12e-02	-0.227000	1.60e-01
REACTOME RAF INDEPENDENT MAPK1 3 ACTIVATION	22	7.12e-02	0.222000	1.60e-01
REACTOME REGULATION OF FZD BY UBIQUITINATION	21	7.14e-02	-0.227000	1.60e-01
REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY	46	7.15e-02	0.154000	1.60e-01
REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES	34	7.15e-02	0.179000	1.60e-01
REACTOME ETHANOL OXIDATION	12	7.20e-02	-0.300000	1.61e-01
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	55	7.26e-02	-0.140000	1.62e-01
REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH	62	7.36e-02	-0.131000	1.64e-01
REACTOME UNWINDING OF DNA	12	7.37e-02	0.298000	1.64e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES	10	7.47e-02	0.325000	1.66e-01
REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	16	7.49e-02	0.257000	1.66e-01
REACTOME STRIATED MUSCLE CONTRACTION	35	7.52e-02	-0.174000	1.67e-01
REACTOME CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2	11	7.54e-02	0.310000	1.67e-01
REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	24	7.59e-02	-0.209000	1.68e-01
REACTOME SIGNALING BY ERYTHROPOIETIN	25	7.61e-02	0.205000	1.68e-01
REACTOME REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION	9	7.64e-02	0.341000	1.68e-01
REACTOME MTORC1 MEDIATED SIGNALLING	23	7.68e-02	0.213000	1.69e-01
REACTOME RHOV GTPASE CYCLE	36	7.73e-02	0.170000	1.70e-01
REACTOME FATTY ACID METABOLISM	170	7.80e-02	0.078400	1.71e-01
REACTOME CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN	45	7.80e-02	-0.152000	1.71e-01
REACTOME VITAMINS	6	7.85e-02	-0.415000	1.72e-01
REACTOME RRNA MODIFICATION IN THE MITOCHONDRION	6	7.88e-02	0.414000	1.72e-01
REACTOME DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS	25	7.90e-02	0.203000	1.73e-01
REACTOME MET PROMOTES CELL MOTILITY	41	7.92e-02	-0.158000	1.73e-01
REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	8	7.93e-02	0.358000	1.73e-01
REACTOME PI3K EVENTS IN ERBB2 SIGNALING	16	7.93e-02	-0.253000	1.73e-01
REACTOME RA BIOSYNTHESIS PATHWAY	22	7.99e-02	-0.216000	1.73e-01
REACTOME ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS	20	8.01e-02	0.226000	1.74e-01
REACTOME FCERI MEDIATED MAPK ACTIVATION	32	8.08e-02	0.178000	1.75e-01
REACTOME DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1	9	8.09e-02	0.336000	1.75e-01
REACTOME VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS	42	8.12e-02	0.155000	1.76e-01
REACTOME PLASMA LIPOPROTEIN CLEARANCE	37	8.17e-02	0.165000	1.76e-01
REACTOME BICARBONATE TRANSPORTERS	10	8.23e-02	-0.317000	1.77e-01
REACTOME METALLOTHIONEINS BIND METALS	11	8.26e-02	-0.302000	1.78e-01
REACTOME TERMINAL PATHWAY OF COMPLEMENT	8	8.32e-02	-0.354000	1.79e-01
REACTOME NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION	20	8.32e-02	-0.224000	1.79e-01
REACTOME RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS	5	8.40e-02	-0.446000	1.80e-01
REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	19	8.41e-02	-0.229000	1.80e-01
REACTOME ANDROGEN BIOSYNTHESIS	11	8.48e-02	-0.300000	1.81e-01
REACTOME AMINO ACID CONJUGATION	9	8.50e-02	-0.332000	1.81e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2	13	8.52e-02	0.276000	1.81e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE GIP	12	8.53e-02	-0.287000	1.81e-01
REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS	55	8.53e-02	-0.134000	1.81e-01
REACTOME ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY	5	8.55e-02	-0.444000	1.82e-01
REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS	8	8.58e-02	-0.351000	1.82e-01
REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	11	8.59e-02	0.299000	1.82e-01
REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	9	8.67e-02	-0.330000	1.83e-01
REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY	26	8.69e-02	0.194000	1.84e-01
REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS	16	8.76e-02	-0.247000	1.85e-01
REACTOME ONCOGENIC MAPK SIGNALING	79	8.78e-02	0.111000	1.85e-01
REACTOME GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION	14	8.82e-02	0.263000	1.86e-01
REACTOME RESPONSE OF MTB TO PHAGOCYTOSIS	22	8.83e-02	0.210000	1.86e-01
REACTOME VXPX CARGO TARGETING TO CILIUM	20	8.89e-02	0.220000	1.86e-01
REACTOME LIGAND RECEPTOR INTERACTIONS	8	8.89e-02	-0.347000	1.86e-01
REACTOME TNFR1 INDUCED PROAPOPTOTIC SIGNALING	23	8.91e-02	0.205000	1.86e-01
REACTOME CREATINE METABOLISM	9	8.92e-02	-0.327000	1.86e-01
REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS	16	8.92e-02	-0.245000	1.86e-01
REACTOME SARS COV 1 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS	16	8.92e-02	0.245000	1.86e-01
REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS	63	8.93e-02	0.124000	1.86e-01
REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER	77	9.02e-02	-0.112000	1.88e-01
REACTOME INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING	103	9.19e-02	-0.096100	1.91e-01
REACTOME TRAF6 MEDIATED NF KB ACTIVATION	24	9.24e-02	0.198000	1.92e-01
REACTOME RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES	16	9.25e-02	-0.243000	1.92e-01
REACTOME REGULATION OF RUNX1 EXPRESSION AND ACTIVITY	17	9.42e-02	0.234000	1.95e-01
REACTOME ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS	87	9.42e-02	-0.104000	1.95e-01
REACTOME PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS	21	9.54e-02	0.210000	1.97e-01
REACTOME REGULATION OF IFNA IFNB SIGNALING	23	9.55e-02	0.201000	1.97e-01
REACTOME PHASE 2 PLATEAU PHASE	14	9.56e-02	-0.257000	1.97e-01
REACTOME INTERLEUKIN 12 SIGNALING	43	9.58e-02	0.147000	1.97e-01
REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	28	9.64e-02	0.182000	1.98e-01
REACTOME VEGFR2 MEDIATED CELL PROLIFERATION	19	9.66e-02	0.220000	1.98e-01
REACTOME BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA	5	9.75e-02	0.428000	2.00e-01
REACTOME KSRP KHSRP BINDS AND DESTABILIZES MRNA	17	9.80e-02	0.232000	2.01e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE	5	9.90e-02	0.426000	2.02e-01
REACTOME GENERATION OF SECOND MESSENGER MOLECULES	30	9.90e-02	0.174000	2.02e-01
REACTOME LOSS OF FUNCTION OF SMAD2 3 IN CANCER	7	9.91e-02	0.360000	2.02e-01
REACTOME INACTIVATION OF CSF3 G CSF SIGNALING	25	9.99e-02	0.190000	2.03e-01
REACTOME TRP CHANNELS	27	1.00e-01	-0.183000	2.04e-01
REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	20	1.00e-01	0.212000	2.04e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	27	1.01e-01	0.182000	2.05e-01
REACTOME PREVENTION OF PHAGOSOMAL LYSOSOMAL FUSION	9	1.02e-01	0.315000	2.07e-01
REACTOME SYNTHESIS OF PA	38	1.03e-01	0.153000	2.08e-01
REACTOME SIGNALING BY FGFR2 IIIA TM	19	1.03e-01	0.216000	2.08e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1	31	1.03e-01	-0.169000	2.08e-01
REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	17	1.03e-01	-0.228000	2.08e-01
REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	21	1.03e-01	-0.205000	2.08e-01
REACTOME HDR THROUGH MMEJ ALT NHEJ	12	1.05e-01	0.270000	2.11e-01
REACTOME OTHER SEMAPHORIN INTERACTIONS	18	1.06e-01	-0.220000	2.12e-01
REACTOME SIGNAL ATTENUATION	10	1.07e-01	0.295000	2.14e-01
REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	24	1.07e-01	0.190000	2.15e-01
REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	20	1.07e-01	0.208000	2.15e-01
REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	353	1.08e-01	0.049800	2.16e-01
REACTOME PI 3K CASCADE FGFR3	17	1.09e-01	-0.224000	2.18e-01
REACTOME SYNTHESIS OF 5 EICOSATETRAENOIC ACIDS	9	1.09e-01	0.308000	2.18e-01
REACTOME CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY	12	1.10e-01	0.266000	2.19e-01
REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	160	1.11e-01	0.073000	2.21e-01
REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA	11	1.11e-01	-0.277000	2.21e-01
REACTOME TRAIL SIGNALING	8	1.11e-01	0.325000	2.21e-01
REACTOME G PROTEIN ACTIVATION	24	1.11e-01	0.188000	2.21e-01
REACTOME SIGNALING BY EGFR	49	1.12e-01	0.131000	2.21e-01
REACTOME ORGANIC ANION TRANSPORT	5	1.12e-01	-0.410000	2.22e-01
REACTOME ERK MAPK TARGETS	20	1.12e-01	0.205000	2.22e-01
REACTOME SIGNALLING TO ERKS	34	1.13e-01	0.157000	2.23e-01
REACTOME CD28 DEPENDENT VAV1 PATHWAY	11	1.13e-01	0.276000	2.23e-01
REACTOME P38MAPK EVENTS	13	1.14e-01	0.253000	2.25e-01
REACTOME RESPONSE TO METAL IONS	14	1.14e-01	-0.244000	2.25e-01
REACTOME INTRA GOLGI TRAFFIC	43	1.15e-01	0.139000	2.26e-01
REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES	27	1.15e-01	0.175000	2.26e-01
REACTOME DISEASES OF MISMATCH REPAIR MMR	5	1.15e-01	0.407000	2.26e-01
REACTOME ERBB2 REGULATES CELL MOTILITY	15	1.16e-01	-0.235000	2.26e-01
REACTOME INITIAL TRIGGERING OF COMPLEMENT	21	1.16e-01	-0.198000	2.27e-01
REACTOME ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING	23	1.18e-01	0.188000	2.30e-01
REACTOME NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	11	1.18e-01	0.272000	2.30e-01
REACTOME LIPOPHAGY	9	1.19e-01	0.300000	2.31e-01
REACTOME RECEPTOR MEDIATED MITOPHAGY	10	1.19e-01	0.285000	2.31e-01
REACTOME FCGR3A MEDIATED IL10 SYNTHESIS	36	1.19e-01	0.150000	2.32e-01
REACTOME COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC	98	1.19e-01	0.091100	2.32e-01
REACTOME RHOQ GTPASE CYCLE	57	1.20e-01	0.119000	2.32e-01
REACTOME CHOLESTEROL BIOSYNTHESIS	25	1.20e-01	0.180000	2.33e-01
REACTOME RUNX3 REGULATES P14 ARF	10	1.21e-01	0.284000	2.33e-01
REACTOME NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	19	1.21e-01	0.205000	2.34e-01
REACTOME DAP12 SIGNALING	27	1.21e-01	0.172000	2.34e-01
REACTOME RHO GTPASES ACTIVATE NADPH OXIDASES	21	1.22e-01	0.195000	2.35e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1	25	1.23e-01	0.178000	2.37e-01
REACTOME SUMO IS CONJUGATED TO E1 UBA2 SAE1	5	1.23e-01	0.398000	2.37e-01
REACTOME INTERLEUKIN 15 SIGNALING	13	1.24e-01	0.247000	2.38e-01
REACTOME NFE2L2 REGULATING ANTI OXIDANT DETOXIFICATION ENZYMES	17	1.25e-01	0.215000	2.40e-01
REACTOME TLR3 MEDIATED TICAM1 DEPENDENT PROGRAMMED CELL DEATH	6	1.25e-01	0.361000	2.40e-01
REACTOME ONCOGENE INDUCED SENESCENCE	35	1.26e-01	0.150000	2.40e-01
REACTOME ABACAVIR TRANSMEMBRANE TRANSPORT	5	1.26e-01	-0.395000	2.41e-01
REACTOME AQUAPORIN MEDIATED TRANSPORT	51	1.26e-01	0.124000	2.41e-01
REACTOME METABOLISM OF NUCLEOTIDES	94	1.27e-01	0.091100	2.42e-01
REACTOME SEMA4D IN SEMAPHORIN SIGNALING	24	1.27e-01	0.180000	2.42e-01
REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE	5	1.29e-01	-0.392000	2.45e-01
REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES	37	1.29e-01	-0.144000	2.45e-01
REACTOME FREE FATTY ACIDS REGULATE INSULIN SECRETION	10	1.29e-01	-0.277000	2.45e-01
REACTOME RHOH GTPASE CYCLE	37	1.29e-01	0.144000	2.45e-01
REACTOME RHOBTB1 GTPASE CYCLE	22	1.30e-01	0.187000	2.46e-01
REACTOME BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA	5	1.30e-01	0.391000	2.47e-01
REACTOME PI 3K CASCADE FGFR2	22	1.31e-01	-0.186000	2.48e-01
REACTOME NECTIN NECL TRANS HETERODIMERIZATION	7	1.32e-01	-0.329000	2.48e-01
REACTOME INSULIN RECEPTOR RECYCLING	29	1.32e-01	0.161000	2.50e-01
REACTOME SERINE BIOSYNTHESIS	9	1.33e-01	0.289000	2.50e-01
REACTOME COHESIN LOADING ONTO CHROMATIN	8	1.34e-01	0.306000	2.51e-01
REACTOME LDL REMODELING	6	1.34e-01	-0.353000	2.52e-01
REACTOME G2 PHASE	5	1.35e-01	-0.386000	2.53e-01
REACTOME RIPK1 MEDIATED REGULATED NECROSIS	30	1.35e-01	0.158000	2.53e-01
REACTOME ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING	9	1.36e-01	-0.287000	2.55e-01
REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	15	1.37e-01	0.222000	2.55e-01
REACTOME DISSOLUTION OF FIBRIN CLOT	13	1.37e-01	-0.238000	2.55e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES	16	1.37e-01	0.215000	2.55e-01
REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	9	1.37e-01	0.286000	2.55e-01
REACTOME ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA	15	1.38e-01	0.221000	2.57e-01
REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	59	1.38e-01	0.112000	2.57e-01
REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	15	1.40e-01	-0.220000	2.59e-01
REACTOME RHOG GTPASE CYCLE	71	1.40e-01	0.101000	2.59e-01
REACTOME FLT3 SIGNALING IN DISEASE	28	1.40e-01	0.161000	2.59e-01
REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	101	1.41e-01	-0.084800	2.60e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN	13	1.41e-01	-0.236000	2.60e-01
REACTOME MITOTIC TELOPHASE CYTOKINESIS	11	1.41e-01	0.256000	2.61e-01
REACTOME DNA DAMAGE REVERSAL	8	1.42e-01	0.300000	2.61e-01
REACTOME POLO LIKE KINASE MEDIATED EVENTS	16	1.42e-01	0.212000	2.62e-01
REACTOME RAC3 GTPASE CYCLE	85	1.42e-01	0.092000	2.62e-01
REACTOME RHO GTPASES ACTIVATE ROCKS	19	1.43e-01	0.194000	2.62e-01
REACTOME SIGNALING BY FGFR IN DISEASE	62	1.43e-01	0.107000	2.63e-01
REACTOME PI 3K CASCADE FGFR4	19	1.44e-01	-0.194000	2.64e-01
REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	13	1.44e-01	0.234000	2.64e-01
REACTOME INTRAFLAGELLAR TRANSPORT	50	1.44e-01	0.119000	2.64e-01
REACTOME DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE	76	1.46e-01	0.096600	2.66e-01
REACTOME SUMO IS PROTEOLYTICALLY PROCESSED	6	1.47e-01	0.342000	2.68e-01
REACTOME CA2 PATHWAY	62	1.47e-01	0.106000	2.68e-01
REACTOME SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS	12	1.47e-01	0.242000	2.68e-01
REACTOME DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B	7	1.48e-01	0.316000	2.69e-01
REACTOME NEGATIVE REGULATION OF FLT3	15	1.48e-01	0.216000	2.70e-01
REACTOME INTERFERON ALPHA BETA SIGNALING	70	1.49e-01	0.099800	2.70e-01
REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	129	1.49e-01	0.073600	2.70e-01
REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING	34	1.49e-01	0.143000	2.70e-01
REACTOME SIGNALING BY ERBB4	57	1.50e-01	-0.110000	2.71e-01
REACTOME FRS MEDIATED FGFR3 SIGNALING	19	1.51e-01	-0.190000	2.74e-01
REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES	34	1.52e-01	0.142000	2.74e-01
REACTOME PHASE II CONJUGATION OF COMPOUNDS	102	1.52e-01	-0.082100	2.74e-01
REACTOME DECTIN 2 FAMILY	26	1.53e-01	-0.162000	2.75e-01
REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	16	1.53e-01	0.206000	2.76e-01
REACTOME MAPK3 ERK1 ACTIVATION	10	1.54e-01	0.260000	2.77e-01
REACTOME IRON UPTAKE AND TRANSPORT	56	1.54e-01	0.110000	2.77e-01
REACTOME METAL ION SLC TRANSPORTERS	23	1.55e-01	0.171000	2.77e-01
REACTOME PRE NOTCH PROCESSING IN GOLGI	18	1.55e-01	0.194000	2.77e-01
REACTOME RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR	19	1.56e-01	-0.188000	2.78e-01
REACTOME ADRENOCEPTORS	9	1.56e-01	-0.273000	2.78e-01
REACTOME SYNTHESIS OF GDP MANNOSE	5	1.56e-01	0.367000	2.78e-01
REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	51	1.56e-01	0.115000	2.79e-01
REACTOME ORGANIC ANION TRANSPORTERS	10	1.56e-01	-0.259000	2.79e-01
REACTOME NUCLEAR SIGNALING BY ERBB4	32	1.57e-01	-0.145000	2.79e-01
REACTOME RAF ACTIVATION	33	1.57e-01	0.142000	2.80e-01
REACTOME SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS	43	1.58e-01	0.124000	2.80e-01
REACTOMEMATURATION OF SARS COV 1 NUCLEOPROTEIN	11	1.59e-01	0.246000	2.81e-01
REACTOME LAMININ INTERACTIONS	28	1.59e-01	-0.154000	2.82e-01
REACTOME RSK ACTIVATION	5	1.61e-01	0.362000	2.85e-01
REACTOME INTERLEUKIN 6 SIGNALING	11	1.61e-01	0.244000	2.85e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX IN CANCER	8	1.61e-01	0.286000	2.85e-01
REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	12	1.61e-01	0.233000	2.85e-01
REACTOME GAP JUNCTION TRAFFICKING AND REGULATION	49	1.61e-01	-0.116000	2.85e-01
REACTOME SIGNALING BY SCF KIT	42	1.62e-01	0.125000	2.85e-01
REACTOME RND3 GTPASE CYCLE	41	1.64e-01	0.126000	2.88e-01
REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES	29	1.65e-01	0.149000	2.91e-01
REACTOME ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS	7	1.66e-01	0.303000	2.91e-01
REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	16	1.68e-01	-0.199000	2.94e-01
REACTOME FORMATION OF LATERAL PLATE MESODERM	5	1.68e-01	-0.356000	2.95e-01
REACTOME SIGNALING BY BMP	27	1.68e-01	0.153000	2.95e-01
REACTOME FRS MEDIATED FGFR2 SIGNALING	24	1.69e-01	-0.162000	2.96e-01
REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION	23	1.70e-01	-0.165000	2.98e-01
REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	46	1.71e-01	0.117000	2.98e-01
REACTOME FGFR2B LIGAND BINDING AND ACTIVATION	10	1.71e-01	-0.250000	2.98e-01
REACTOME SHC MEDIATED CASCADE FGFR3	17	1.71e-01	-0.192000	2.98e-01
REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	11	1.73e-01	0.237000	3.00e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1	16	1.74e-01	0.196000	3.02e-01
REACTOME ATORVASTATIN ADME	9	1.74e-01	-0.262000	3.02e-01
REACTOME CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION	11	1.74e-01	0.237000	3.02e-01
REACTOME PLATELET CALCIUM HOMEOSTASIS	27	1.74e-01	0.151000	3.02e-01
REACTOME AMYLOID FIBER FORMATION	102	1.75e-01	0.077700	3.03e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE	5	1.76e-01	0.350000	3.03e-01
REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	30	1.76e-01	0.143000	3.03e-01
REACTOME MASTL FACILITATES MITOTIC PROGRESSION	10	1.76e-01	0.247000	3.03e-01
REACTOME RAB GERANYLGERANYLATION	57	1.76e-01	0.104000	3.03e-01
REACTOME EFFECTS OF PIP2 HYDROLYSIS	26	1.77e-01	0.153000	3.04e-01
REACTOME PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1	9	1.77e-01	0.260000	3.04e-01
REACTOME SIGNALING BY NOTCH2	32	1.77e-01	0.138000	3.04e-01
REACTOME GABA RECEPTOR ACTIVATION	57	1.77e-01	-0.103000	3.04e-01
REACTOME ZINC TRANSPORTERS	15	1.77e-01	0.201000	3.04e-01
REACTOME RIBAVIRIN ADME	11	1.78e-01	0.235000	3.05e-01
REACTOME PHYSIOLOGICAL FACTORS	14	1.79e-01	-0.208000	3.06e-01
REACTOME CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND	16	1.79e-01	0.194000	3.06e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA	27	1.79e-01	0.149000	3.06e-01
REACTOME DEFENSINS	33	1.81e-01	-0.134000	3.09e-01
REACTOME RHOBTB2 GTPASE CYCLE	22	1.83e-01	0.164000	3.11e-01
REACTOME CYCLIN D ASSOCIATED EVENTS IN G1	46	1.83e-01	0.113000	3.12e-01
REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY	5	1.88e-01	0.340000	3.20e-01
REACTOME GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION	7	1.88e-01	-0.287000	3.20e-01
REACTOME CALCINEURIN ACTIVATES NFAT	9	1.88e-01	0.253000	3.20e-01
REACTOME FRS MEDIATED FGFR4 SIGNALING	21	1.89e-01	-0.166000	3.20e-01
REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION	35	1.90e-01	0.128000	3.22e-01
REACTOME SYNAPTIC ADHESION LIKE MOLECULES	19	1.91e-01	-0.173000	3.23e-01
REACTOME SIGNALING BY ERBB2 ECD MUTANTS	16	1.92e-01	0.188000	3.25e-01
REACTOME ACTIVATION OF SMO	18	1.95e-01	-0.177000	3.28e-01
REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	16	1.96e-01	0.187000	3.31e-01
REACTOME PEROXISOMAL PROTEIN IMPORT	62	1.97e-01	0.094700	3.32e-01
REACTOME SIGNALLING TO RAS	20	1.97e-01	0.167000	3.32e-01
REACTOME REGULATED NECROSIS	57	1.98e-01	0.098500	3.33e-01
REACTOME CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION	24	1.99e-01	0.151000	3.34e-01
REACTOME SELECTIVE AUTOPHAGY	79	1.99e-01	0.083600	3.34e-01
REACTOME EICOSANOID LIGAND BINDING RECEPTORS	14	1.99e-01	0.198000	3.34e-01
REACTOME ACTIVATION OF CASPASES THROUGH APOPTOSOME MEDIATED CLEAVAGE	5	2.01e-01	0.330000	3.37e-01
REACTOME SUPPRESSION OF APOPTOSIS	7	2.02e-01	0.278000	3.38e-01
REACTOME TRANSPORT AND SYNTHESIS OF PAPS	6	2.03e-01	0.300000	3.39e-01
REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING	12	2.04e-01	0.212000	3.41e-01
REACTOME INTERLEUKIN 12 FAMILY SIGNALING	53	2.05e-01	0.101000	3.42e-01
REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES	14	2.06e-01	0.195000	3.42e-01
REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	14	2.06e-01	0.195000	3.43e-01
REACTOME REGULATION OF PTEN LOCALIZATION	8	2.08e-01	0.257000	3.45e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE	8	2.08e-01	0.257000	3.45e-01
REACTOME METABOLISM OF FOLATE AND PTERINES	17	2.08e-01	0.176000	3.45e-01
REACTOME FATTY ACIDS BOUND TO GPR40 FFAR1 REGULATE INSULIN SECRETION	8	2.10e-01	-0.256000	3.48e-01
REACTOME ALK MUTANTS BIND TKIS	12	2.10e-01	0.209000	3.48e-01
REACTOME UPTAKE AND FUNCTION OF ANTHRAX TOXINS	11	2.11e-01	0.218000	3.49e-01
REACTOME OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS	8	2.13e-01	-0.254000	3.51e-01
REACTOME G0 AND EARLY G1	27	2.13e-01	0.138000	3.51e-01
REACTOME SYNTHESIS OF DOLICHYL PHOSPHATE	6	2.13e-01	0.293000	3.52e-01
REACTOME SIGNALING BY MST1	5	2.14e-01	-0.321000	3.52e-01
REACTOME SHC MEDIATED CASCADE FGFR4	19	2.14e-01	-0.165000	3.53e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE	74	2.15e-01	0.083300	3.54e-01
REACTOME ASPARTATE AND ASPARAGINE METABOLISM	11	2.16e-01	-0.216000	3.54e-01
REACTOME CIPROFLOXACIN ADME	5	2.16e-01	-0.319000	3.55e-01
REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	26	2.17e-01	0.140000	3.56e-01
REACTOME ION CHANNEL TRANSPORT	172	2.18e-01	-0.054500	3.57e-01
REACTOME DEX H BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION	7	2.19e-01	0.268000	3.58e-01
REACTOME DISEASES OF CARBOHYDRATE METABOLISM	31	2.19e-01	0.128000	3.58e-01
REACTOME TRNA MODIFICATION IN THE MITOCHONDRION	8	2.19e-01	0.251000	3.58e-01
REACTOME CREB3 FACTORS ACTIVATE GENES	8	2.22e-01	0.249000	3.63e-01
REACTOME RUNX3 REGULATES WNT SIGNALING	8	2.26e-01	0.247000	3.68e-01
REACTOME METABOLISM OF PORPHYRINS	26	2.27e-01	0.137000	3.70e-01
REACTOME NETRIN MEDIATED REPULSION SIGNALS	8	2.28e-01	-0.246000	3.71e-01
REACTOME ACYL CHAIN REMODELLING OF PG	18	2.29e-01	-0.164000	3.72e-01
REACTOME HYALURONAN UPTAKE AND DEGRADATION	12	2.29e-01	0.200000	3.72e-01
REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	16	2.30e-01	0.173000	3.73e-01
REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	14	2.31e-01	-0.185000	3.75e-01
REACTOME DEFECTIVE F9 ACTIVATION	5	2.35e-01	0.307000	3.80e-01
REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	13	2.35e-01	0.190000	3.80e-01
REACTOME THE ACTIVATION OF ARYLSULFATASES	8	2.37e-01	0.242000	3.82e-01
REACTOME DEFECTIVE CHST6 CAUSES MCDC1	8	2.38e-01	-0.241000	3.83e-01
REACTOME OTHER INTERLEUKIN SIGNALING	24	2.38e-01	0.139000	3.84e-01
REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION	6	2.40e-01	0.277000	3.86e-01
REACTOME RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS	9	2.40e-01	0.226000	3.86e-01
REACTOME REGULATION OF INSULIN SECRETION	77	2.40e-01	-0.077400	3.86e-01
REACTOME TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS	36	2.42e-01	0.113000	3.89e-01
REACTOME RUNX3 REGULATES CDKN1A TRANSCRIPTION	7	2.43e-01	0.255000	3.89e-01
REACTOME ACTIVATION OF TRKA RECEPTORS	6	2.43e-01	-0.275000	3.89e-01
REACTOME HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS	7	2.45e-01	-0.254000	3.92e-01
REACTOME SYNTHESIS OF DIPHTHAMIDE EEF2	8	2.46e-01	0.237000	3.93e-01
REACTOME SENSORY PERCEPTION OF TASTE	47	2.46e-01	-0.097700	3.94e-01
REACTOME ELASTIC FIBRE FORMATION	44	2.47e-01	-0.101000	3.95e-01
REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	15	2.49e-01	-0.172000	3.96e-01
REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS	5	2.49e-01	-0.298000	3.96e-01
REACTOME MET INTERACTS WITH TNS PROTEINS	5	2.49e-01	-0.297000	3.97e-01
REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX	13	2.53e-01	0.183000	4.03e-01
REACTOME FRUCTOSE METABOLISM	7	2.54e-01	0.249000	4.04e-01
REACTOME FREE FATTY ACID RECEPTORS	5	2.55e-01	-0.294000	4.05e-01
REACTOME GAB1 SIGNALOSOME	17	2.55e-01	0.159000	4.05e-01
REACTOME MAP2K AND MAPK ACTIVATION	38	2.57e-01	0.106000	4.07e-01
REACTOME COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM	21	2.57e-01	0.143000	4.07e-01
REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION	19	2.60e-01	-0.149000	4.10e-01
REACTOME CONSTITUTIVE SIGNALING BY EGFRVIII	15	2.60e-01	0.168000	4.10e-01
REACTOME CD22 MEDIATED BCR REGULATION	5	2.60e-01	0.291000	4.10e-01
REACTOME PROLACTIN RECEPTOR SIGNALING	15	2.61e-01	-0.168000	4.10e-01
REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	54	2.61e-01	0.088500	4.10e-01
REACTOME CALCITONIN LIKE LIGAND RECEPTORS	10	2.62e-01	-0.205000	4.12e-01
REACTOME CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY	25	2.62e-01	0.130000	4.12e-01
REACTOME CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS	19	2.62e-01	0.149000	4.12e-01
REACTOME SIGNALING BY FLT3 FUSION PROTEINS	19	2.62e-01	0.149000	4.12e-01
REACTOME BINDING OF TCF LEF CTNNB1 TO TARGET GENE PROMOTERS	8	2.63e-01	0.229000	4.12e-01
REACTOME RHOF GTPASE CYCLE	40	2.63e-01	0.102000	4.12e-01
REACTOME INTERLEUKIN 23 SIGNALING	9	2.64e-01	0.215000	4.12e-01
REACTOME CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS	100	2.65e-01	0.064500	4.14e-01
REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION	26	2.68e-01	0.126000	4.18e-01
REACTOME SCAVENGING BY CLASS B RECEPTORS	6	2.68e-01	-0.261000	4.18e-01
REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	11	2.70e-01	0.192000	4.20e-01
REACTOME SUPPRESSION OF PHAGOSOMAL MATURATION	13	2.70e-01	0.177000	4.20e-01
REACTOME ARACHIDONIC ACID METABOLISM	57	2.71e-01	-0.084300	4.21e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS	9	2.72e-01	0.212000	4.22e-01
REACTOME RND1 GTPASE CYCLE	41	2.72e-01	0.099100	4.23e-01
REACTOME SUMOYLATION OF DNA METHYLATION PROTEINS	16	2.73e-01	0.158000	4.23e-01
REACTOME INLA MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS	9	2.74e-01	0.210000	4.25e-01
REACTOME SIGNALING BY ERBB2	50	2.75e-01	0.089300	4.25e-01
REACTOME SIGNALING BY FGFR2	72	2.75e-01	0.074300	4.26e-01
REACTOME TRANSLESION SYNTHESIS BY POLK	17	2.76e-01	0.153000	4.27e-01
REACTOME SIGNALLING TO P38 VIA RIT AND RIN	5	2.78e-01	-0.280000	4.29e-01
REACTOME SIGNALING BY EGFR IN CANCER	25	2.78e-01	0.125000	4.29e-01
REACTOME G ALPHA 12 13 SIGNALLING EVENTS	74	2.79e-01	0.072800	4.29e-01
REACTOME SYNTHESIS OF PIPS AT THE ER MEMBRANE	5	2.79e-01	0.280000	4.29e-01
REACTOME LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS	19	2.79e-01	0.143000	4.29e-01
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY	94	2.79e-01	0.064500	4.29e-01
REACTOME LYSINE CATABOLISM	12	2.80e-01	-0.180000	4.29e-01
REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	22	2.80e-01	0.133000	4.29e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS	11	2.80e-01	0.188000	4.29e-01
REACTOME RHOA GTPASE CYCLE	142	2.82e-01	0.052300	4.32e-01
REACTOME SARS COV 1 HOST INTERACTIONS	92	2.84e-01	0.064700	4.34e-01
REACTOME SOS MEDIATED SIGNALLING	7	2.84e-01	0.234000	4.34e-01
REACTOME ACYL CHAIN REMODELLING OF PC	27	2.85e-01	-0.119000	4.35e-01
REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	89	2.85e-01	0.065600	4.35e-01
REACTOME DEFECTIVE B4GALT1 CAUSES B4GALT1 CDG CDG 2D	8	2.85e-01	-0.218000	4.35e-01
REACTOME TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS	82	2.86e-01	-0.068100	4.36e-01
REACTOME RUNX3 REGULATES BCL2L11 BIM TRANSCRIPTION	5	2.87e-01	0.275000	4.37e-01
REACTOME GLUTAMATE AND GLUTAMINE METABOLISM	13	2.90e-01	0.169000	4.41e-01
REACTOME IKBA VARIANT LEADS TO EDA ID	6	2.91e-01	0.249000	4.42e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS	5	2.92e-01	-0.272000	4.42e-01
REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	12	2.94e-01	0.175000	4.45e-01
REACTOME LDL CLEARANCE	19	2.94e-01	0.139000	4.45e-01
REACTOME GRB7 EVENTS IN ERBB2 SIGNALING	5	2.94e-01	-0.271000	4.45e-01
REACTOME KERATAN SULFATE KERATIN METABOLISM	34	2.95e-01	0.104000	4.45e-01
REACTOME ESTABLISHMENT OF SISTER CHROMATID COHESION	9	2.95e-01	0.202000	4.45e-01
REACTOME MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS	13	2.98e-01	0.167000	4.50e-01
REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS	12	3.01e-01	-0.172000	4.54e-01
REACTOME MIRO GTPASE CYCLE	8	3.02e-01	0.211000	4.54e-01
REACTOME SYNTHESIS OF LIPOXINS LX	6	3.02e-01	0.243000	4.54e-01
REACTOME CHL1 INTERACTIONS	9	3.02e-01	-0.199000	4.54e-01
REACTOME CROSSLINKING OF COLLAGEN FIBRILS	16	3.04e-01	-0.148000	4.56e-01
REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER	18	3.04e-01	0.140000	4.56e-01
REACTOME TRANSPORT OF RCBL WITHIN THE BODY	8	3.04e-01	0.210000	4.56e-01
REACTOME CYTOCHROME C MEDIATED APOPTOTIC RESPONSE	12	3.07e-01	0.170000	4.59e-01
REACTOME REGULATION OF NPAS4 GENE EXPRESSION	13	3.07e-01	0.164000	4.59e-01
REACTOME CONDENSATION OF PROMETAPHASE CHROMOSOMES	11	3.07e-01	0.178000	4.59e-01
REACTOME SIGNALING BY PDGFR IN DISEASE	20	3.07e-01	0.132000	4.59e-01
REACTOME ACYL CHAIN REMODELING OF DAG AND TAG	5	3.08e-01	0.263000	4.59e-01
REACTOME SIGNALING BY INSULIN RECEPTOR	80	3.09e-01	0.065800	4.60e-01
REACTOME FORMATION OF XYLULOSE 5 PHOSPHATE	5	3.09e-01	0.263000	4.60e-01
REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	32	3.11e-01	0.103000	4.62e-01
REACTOME SIGNALING BY MAPK MUTANTS	6	3.11e-01	0.239000	4.62e-01
REACTOME DNA REPLICATION INITIATION	7	3.12e-01	0.221000	4.63e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES	8	3.12e-01	-0.206000	4.63e-01
REACTOME HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS	9	3.13e-01	-0.194000	4.63e-01
REACTOME PINK1 PRKN MEDIATED MITOPHAGY	22	3.14e-01	0.124000	4.65e-01
REACTOME SMAC XIAP REGULATED APOPTOTIC RESPONSE	7	3.15e-01	0.220000	4.65e-01
REACTOME FBXW7 MUTANTS AND NOTCH1 IN CANCER	5	3.15e-01	0.260000	4.65e-01
REACTOME ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY	10	3.15e-01	0.183000	4.65e-01
REACTOME OVARIAN TUMOR DOMAIN PROTEASES	36	3.16e-01	0.096700	4.66e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS	9	3.18e-01	0.192000	4.68e-01
REACTOME ION HOMEOSTASIS	52	3.20e-01	-0.079800	4.71e-01
REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX	15	3.21e-01	0.148000	4.72e-01
REACTOME NUCLEOTIDE SALVAGE	21	3.22e-01	0.125000	4.72e-01
REACTOME SIALIC ACID METABOLISM	33	3.22e-01	0.099700	4.72e-01
REACTOME SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION	8	3.22e-01	0.202000	4.73e-01
REACTOME NEUROTRANSMITTER CLEARANCE	9	3.23e-01	-0.190000	4.73e-01
REACTOME ACTIVATION OF AMPK DOWNSTREAM OF NMDARS	28	3.24e-01	-0.108000	4.74e-01
REACTOME ACYL CHAIN REMODELLING OF PS	22	3.25e-01	-0.121000	4.75e-01
REACTOME EPH EPHRIN SIGNALING	90	3.25e-01	0.060000	4.76e-01
REACTOME PTK6 PROMOTES HIF1A STABILIZATION	6	3.28e-01	-0.231000	4.78e-01
REACTOME CS DS DEGRADATION	12	3.28e-01	-0.163000	4.78e-01
REACTOME COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC	52	3.28e-01	0.078400	4.78e-01
REACTOME BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS	10	3.28e-01	0.178000	4.79e-01
REACTOME INTERLEUKIN 7 SIGNALING	31	3.30e-01	0.101000	4.80e-01
REACTOME NRCAM INTERACTIONS	6	3.31e-01	-0.229000	4.81e-01
REACTOME FASL CD95L SIGNALING	5	3.32e-01	0.251000	4.82e-01
REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	18	3.34e-01	-0.132000	4.85e-01
REACTOME CHAPERONE MEDIATED AUTOPHAGY	20	3.34e-01	0.125000	4.85e-01
REACTOME SYNTHESIS OF 12 EICOSATETRAENOIC ACID DERIVATIVES	7	3.35e-01	0.211000	4.85e-01
REACTOME LYSOSPHINGOLIPID AND LPA RECEPTORS	14	3.35e-01	-0.149000	4.86e-01
REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL	13	3.38e-01	0.154000	4.89e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR2	29	3.42e-01	-0.102000	4.94e-01
REACTOME INTESTINAL ABSORPTION	5	3.43e-01	-0.245000	4.96e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR3	24	3.44e-01	-0.112000	4.96e-01
REACTOME DEFECTIVE CSF2RB CAUSES SMDP5	7	3.44e-01	-0.206000	4.97e-01
REACTOME SELENOAMINO ACID METABOLISM	108	3.45e-01	0.052600	4.97e-01
REACTOME GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION	42	3.46e-01	0.084100	4.98e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	24	3.46e-01	-0.111000	4.98e-01
REACTOME METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS	122	3.48e-01	0.049200	4.99e-01
REACTOME EGFR TRANSACTIVATION BY GASTRIN	9	3.48e-01	0.181000	4.99e-01
REACTOME METABOLISM OF STEROIDS	150	3.51e-01	0.044100	5.04e-01
REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	10	3.53e-01	-0.169000	5.06e-01
REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	15	3.54e-01	0.138000	5.06e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG	7	3.55e-01	0.202000	5.07e-01
REACTOME CHYLOMICRON REMODELING	10	3.55e-01	-0.169000	5.07e-01
REACTOME G ALPHA Z SIGNALLING EVENTS	48	3.55e-01	0.077100	5.07e-01
REACTOME GAP JUNCTION DEGRADATION	12	3.57e-01	0.153000	5.10e-01
REACTOME PLATELET AGGREGATION PLUG FORMATION	39	3.58e-01	0.085100	5.10e-01
REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS	19	3.60e-01	-0.121000	5.12e-01
REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION	12	3.61e-01	-0.152000	5.13e-01
REACTOME DOWNREGULATION OF ERBB4 SIGNALING	9	3.61e-01	0.176000	5.13e-01
REACTOME MRNA EDITING	10	3.61e-01	0.167000	5.13e-01
REACTOME GLYCOGEN SYNTHESIS	13	3.62e-01	0.146000	5.13e-01
REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION	10	3.62e-01	-0.166000	5.13e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL	15	3.62e-01	-0.136000	5.13e-01
REACTOME DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS	14	3.65e-01	0.140000	5.16e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS	15	3.65e-01	0.135000	5.16e-01
REACTOME PHENYLALANINE METABOLISM	6	3.65e-01	0.214000	5.16e-01
REACTOME OPSINS	7	3.66e-01	-0.197000	5.16e-01
REACTOME INTERLEUKIN 17 SIGNALING	66	3.67e-01	0.064200	5.18e-01
REACTOME MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION	15	3.68e-01	0.134000	5.19e-01
REACTOME NICOTINAMIDE SALVAGING	19	3.70e-01	-0.119000	5.20e-01
REACTOME CATION COUPLED CHLORIDE COTRANSPORTERS	7	3.70e-01	0.196000	5.20e-01
REACTOME REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS	11	3.70e-01	0.156000	5.20e-01
REACTOME SHC1 EVENTS IN ERBB2 SIGNALING	22	3.71e-01	-0.110000	5.21e-01
REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK	17	3.71e-01	0.125000	5.21e-01
REACTOME ACETYLCHOLINE REGULATES INSULIN SECRETION	10	3.72e-01	-0.163000	5.21e-01
REACTOME EPITHELIAL MESENCHYMAL TRANSITION EMT DURING GASTRULATION	7	3.73e-01	-0.194000	5.23e-01
REACTOME EGFR DOWNREGULATION	30	3.74e-01	0.093800	5.23e-01
REACTOME ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA	5	3.75e-01	0.229000	5.24e-01
REACTOME REGULATION OF IFNG SIGNALING	14	3.76e-01	0.137000	5.25e-01
REACTOME VITAMIN C ASCORBATE METABOLISM	8	3.77e-01	0.181000	5.26e-01
REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	122	3.78e-01	-0.046200	5.27e-01
REACTOME CONJUGATION OF BENZOATE WITH GLYCINE	6	3.81e-01	-0.206000	5.31e-01
REACTOME PHENYLALANINE AND TYROSINE METABOLISM	11	3.81e-01	0.153000	5.31e-01
REACTOME SIGNALING BY ACTIVIN	15	3.82e-01	0.130000	5.31e-01
REACTOME MET RECEPTOR RECYCLING	10	3.83e-01	-0.159000	5.32e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS	7	3.83e-01	0.190000	5.33e-01
REACTOME METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION	15	3.85e-01	0.130000	5.35e-01
REACTOME PURINE SALVAGE	12	3.86e-01	0.144000	5.36e-01
REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	9	3.87e-01	0.167000	5.36e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR4	26	3.87e-01	-0.098000	5.36e-01
REACTOME NEGATIVE REGULATION OF MET ACTIVITY	20	3.90e-01	0.111000	5.40e-01
REACTOME TRYPTOPHAN CATABOLISM	14	3.92e-01	-0.132000	5.41e-01
REACTOME DEFECTS IN COBALAMIN B12 METABOLISM	13	3.93e-01	0.137000	5.42e-01
REACTOME INFECTION WITH MYCOBACTERIUM TUBERCULOSIS	25	3.95e-01	0.098300	5.45e-01
REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	17	3.96e-01	0.119000	5.45e-01
REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS	15	3.97e-01	0.126000	5.47e-01
REACTOME RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION	6	3.98e-01	0.199000	5.48e-01
REACTOME RET SIGNALING	40	3.99e-01	0.077000	5.49e-01
REACTOME RELAXIN RECEPTORS	8	4.01e-01	0.171000	5.52e-01
REACTOME TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX	10	4.03e-01	0.153000	5.54e-01
REACTOME INTERLEUKIN 37 SIGNALING	20	4.04e-01	0.108000	5.54e-01
REACTOME REACTIONS SPECIFIC TO THE COMPLEX N GLYCAN SYNTHESIS PATHWAY	10	4.06e-01	0.152000	5.57e-01
REACTOME DIGESTION OF DIETARY CARBOHYDRATE	6	4.09e-01	-0.195000	5.60e-01
REACTOME PYRIMIDINE CATABOLISM	12	4.09e-01	-0.138000	5.60e-01
REACTOME SIGNALING BY PDGF	57	4.11e-01	-0.063000	5.62e-01
REACTOME ACTIVATION OF BH3 ONLY PROTEINS	30	4.12e-01	0.086600	5.63e-01
REACTOME TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY	16	4.13e-01	0.118000	5.63e-01
REACTOME SODIUM CALCIUM EXCHANGERS	11	4.14e-01	-0.142000	5.64e-01
REACTOME DARPP 32 EVENTS	24	4.15e-01	0.096200	5.65e-01
REACTOME REGULATION OF GENE EXPRESSION IN ENDOCRINE COMMITTED NEUROG3 PROGENITOR CELLS	5	4.15e-01	-0.211000	5.65e-01
REACTOME DEGRADATION OF CYSTEINE AND HOMOCYSTEINE	15	4.18e-01	0.121000	5.69e-01
REACTOME REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS	7	4.18e-01	0.177000	5.69e-01
REACTOME LTC4 CYSLTR MEDIATED IL4 PRODUCTION	6	4.19e-01	-0.190000	5.70e-01
REACTOME OPIOID SIGNALLING	89	4.21e-01	0.049300	5.72e-01
REACTOME RECYCLING OF BILE ACIDS AND SALTS	18	4.22e-01	-0.109000	5.72e-01
REACTOME ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION	28	4.22e-01	0.087600	5.72e-01
REACTOME INOSITOL PHOSPHATE METABOLISM	45	4.25e-01	0.068700	5.76e-01
REACTOME SUMOYLATION OF IMMUNE RESPONSE PROTEINS	10	4.26e-01	0.145000	5.76e-01
REACTOME SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER	15	4.26e-01	0.119000	5.76e-01
REACTOME N GLYCAN ANTENNAE ELONGATION	15	4.28e-01	0.118000	5.76e-01
REACTOME FORMATION OF APOPTOSOME	10	4.28e-01	0.145000	5.76e-01
REACTOME BETA OXIDATION OF PRISTANOYL COA	9	4.29e-01	0.152000	5.76e-01
REACTOME SIGNALING BY RNF43 MUTANTS	8	4.29e-01	-0.162000	5.76e-01
REACTOME VITAMIN B1 THIAMIN METABOLISM	5	4.29e-01	-0.204000	5.76e-01
REACTOME NGF INDEPENDANT TRKA ACTIVATION	5	4.29e-01	-0.204000	5.76e-01
REACTOME SIGNALING BY NTRK3 TRKC	17	4.29e-01	0.111000	5.76e-01
REACTOME ROLE OF ABL IN ROBO SLIT SIGNALING	8	4.29e-01	0.161000	5.76e-01
REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV 1 INFECTION	5	4.30e-01	0.204000	5.76e-01
REACTOME P75NTR SIGNALS VIA NF KB	15	4.31e-01	0.117000	5.77e-01
REACTOME DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15	8	4.32e-01	-0.161000	5.78e-01
REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION	31	4.32e-01	0.081500	5.78e-01
REACTOME TRANSPORT OF ORGANIC ANIONS	10	4.33e-01	-0.143000	5.79e-01
REACTOME TRAFFICKING OF AMPA RECEPTORS	29	4.33e-01	-0.084100	5.79e-01
REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS	21	4.34e-01	-0.098700	5.79e-01
REACTOME SIGNALING BY ALK	26	4.34e-01	0.088700	5.79e-01
REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	13	4.34e-01	0.125000	5.79e-01
REACTOME NGF STIMULATED TRANSCRIPTION	38	4.37e-01	0.072800	5.82e-01
REACTOME COBALAMIN CBL METABOLISM	7	4.37e-01	0.170000	5.82e-01
REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	11	4.38e-01	-0.135000	5.82e-01
REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	11	4.39e-01	0.135000	5.83e-01
REACTOME KILLING MECHANISMS	11	4.41e-01	0.134000	5.86e-01
REACTOME ERYTHROPOIETIN ACTIVATES RAS	14	4.42e-01	0.119000	5.86e-01
REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	17	4.42e-01	0.108000	5.86e-01
REACTOME REGULATION BY C FLIP	11	4.43e-01	0.134000	5.86e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS	14	4.43e-01	0.118000	5.87e-01
REACTOME SIGNALING BY FGFR1 IN DISEASE	38	4.44e-01	0.071800	5.87e-01
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	105	4.45e-01	0.043200	5.87e-01
REACTOME SULFIDE OXIDATION TO SULFATE	6	4.45e-01	0.180000	5.88e-01
REACTOME SPHINGOLIPID METABOLISM	84	4.46e-01	0.048100	5.88e-01
REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX	21	4.46e-01	-0.096100	5.88e-01
REACTOME TRANSPORT OF FATTY ACIDS	8	4.49e-01	-0.155000	5.91e-01
REACTOME BILE ACID AND BILE SALT METABOLISM	45	4.51e-01	-0.064900	5.93e-01
REACTOME NERVOUS SYSTEM DEVELOPMENT	552	4.51e-01	-0.018700	5.94e-01
REACTOME CHYLOMICRON ASSEMBLY	10	4.54e-01	-0.137000	5.96e-01
REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ	6	4.54e-01	0.176000	5.97e-01
REACTOME KERATAN SULFATE DEGRADATION	13	4.55e-01	0.120000	5.97e-01
REACTOME ACTIVATION OF RAC1	12	4.56e-01	0.124000	5.97e-01
REACTOME CREB PHOSPHORYLATION	6	4.58e-01	0.175000	6.00e-01
REACTOME NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS	25	4.59e-01	0.085500	6.01e-01
REACTOME RAP1 SIGNALLING	16	4.61e-01	0.107000	6.02e-01
REACTOME DISEASES OF IMMUNE SYSTEM	29	4.61e-01	0.079100	6.02e-01
REACTOME NEUROTOXICITY OF CLOSTRIDIUM TOXINS	10	4.62e-01	-0.134000	6.03e-01
REACTOME ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA	9	4.62e-01	-0.142000	6.03e-01
REACTOME SYNTHESIS OF UDP N ACETYL GLUCOSAMINE	7	4.64e-01	0.160000	6.04e-01
REACTOME THE PHOTOTRANSDUCTION CASCADE	32	4.64e-01	-0.074800	6.04e-01
REACTOME ACYL CHAIN REMODELLING OF PE	29	4.66e-01	-0.078100	6.07e-01
REACTOME REGULATION OF NPAS4 GENE TRANSCRIPTION	5	4.67e-01	-0.188000	6.07e-01
REACTOME TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT	18	4.77e-01	0.096900	6.19e-01
REACTOME ACTIVATION OF PPARGC1A PGC 1ALPHA BY PHOSPHORYLATION	10	4.77e-01	0.130000	6.20e-01
REACTOME DISEASES ASSOCIATED WITH SURFACTANT METABOLISM	9	4.78e-01	-0.136000	6.20e-01
REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	37	4.80e-01	-0.067000	6.23e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING	6	4.81e-01	0.166000	6.23e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE	11	4.82e-01	0.123000	6.23e-01
REACTOME HISTIDINE CATABOLISM	8	4.84e-01	0.143000	6.25e-01
REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	15	4.84e-01	0.104000	6.25e-01
REACTOME GLYCOSAMINOGLYCAN METABOLISM	118	4.84e-01	-0.037300	6.25e-01
REACTOME ESTROGEN BIOSYNTHESIS	6	4.87e-01	-0.164000	6.28e-01
REACTOME MODULATION BY MTB OF HOST IMMUNE SYSTEM	6	4.87e-01	-0.164000	6.28e-01
REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	45	4.88e-01	-0.059800	6.28e-01
REACTOME TYSND1 CLEAVES PEROXISOMAL PROTEINS	7	4.88e-01	0.151000	6.28e-01
REACTOME RHOB GTPASE CYCLE	67	4.90e-01	0.048800	6.30e-01
REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING	25	4.90e-01	-0.079700	6.30e-01
REACTOME ORGANIC CATION TRANSPORT	10	4.93e-01	-0.125000	6.33e-01
REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	7	4.93e-01	-0.149000	6.33e-01
REACTOME UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN	6	4.94e-01	0.161000	6.33e-01
REACTOME CARGO CONCENTRATION IN THE ER	32	4.95e-01	0.069700	6.34e-01
REACTOME PHOSPHORYLATION OF EMI1	6	4.96e-01	0.161000	6.34e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES	43	4.96e-01	0.060000	6.34e-01
REACTOME REDUCTION OF CYTOSOLIC CA LEVELS	11	4.96e-01	0.118000	6.34e-01
REACTOME RAS SIGNALING DOWNSTREAM OF NF1 LOSS OF FUNCTION VARIANTS	7	4.97e-01	-0.148000	6.34e-01
REACTOME NADE MODULATES DEATH SIGNALLING	5	4.99e-01	0.175000	6.36e-01
REACTOME PI3K AKT ACTIVATION	9	4.99e-01	0.130000	6.37e-01
REACTOME FATTY ACYL COA BIOSYNTHESIS	36	5.02e-01	0.064600	6.40e-01
REACTOME ACTIVATION OF C3 AND C5	6	5.04e-01	-0.157000	6.42e-01
REACTOME HYALURONAN METABOLISM	17	5.07e-01	0.092900	6.45e-01
REACTOME MET ACTIVATES PTPN11	5	5.09e-01	-0.171000	6.47e-01
REACTOME AGGREPHAGY	42	5.09e-01	-0.058800	6.47e-01
REACTOME TIE2 SIGNALING	18	5.10e-01	0.089700	6.47e-01
REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING	29	5.12e-01	0.070300	6.50e-01
REACTOME SYNDECAN INTERACTIONS	26	5.17e-01	-0.073400	6.55e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH PI3K	7	5.19e-01	-0.141000	6.57e-01
REACTOME SIGNALING BY MET	78	5.22e-01	-0.041900	6.60e-01
REACTOME HYALURONAN BIOSYNTHESIS AND EXPORT	5	5.22e-01	-0.165000	6.60e-01
REACTOME ACYL CHAIN REMODELING OF CL	5	5.23e-01	0.165000	6.61e-01
REACTOME JOSEPHIN DOMAIN DUBS	11	5.24e-01	0.111000	6.61e-01
REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	30	5.28e-01	0.066600	6.65e-01
REACTOME INITIATION OF NUCLEAR ENVELOPE NE REFORMATION	18	5.29e-01	0.085600	6.67e-01
REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS	8	5.30e-01	0.128000	6.67e-01
REACTOME ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM	12	5.30e-01	0.105000	6.67e-01
REACTOME SIGNAL TRANSDUCTION BY L1	20	5.32e-01	0.080700	6.69e-01
REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	9	5.33e-01	0.120000	6.70e-01
REACTOME CITRIC ACID CYCLE TCA CYCLE	21	5.34e-01	0.078400	6.70e-01
REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX	9	5.34e-01	0.120000	6.70e-01
REACTOME PURINE CATABOLISM	17	5.36e-01	-0.086700	6.72e-01
REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	16	5.39e-01	-0.088700	6.74e-01
REACTOME SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS	16	5.39e-01	0.088700	6.74e-01
REACTOME HDL CLEARANCE	5	5.39e-01	0.159000	6.74e-01
REACTOME NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS	11	5.40e-01	0.107000	6.74e-01
REACTOME BETA DEFENSINS	27	5.46e-01	-0.067200	6.82e-01
REACTOME SIGNALING BY NTRK2 TRKB	25	5.50e-01	0.069000	6.87e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES	12	5.51e-01	0.099300	6.87e-01
REACTOME GLUCONEOGENESIS	33	5.52e-01	-0.059900	6.87e-01
REACTOME ARYL HYDROCARBON RECEPTOR SIGNALLING	6	5.53e-01	0.140000	6.88e-01
REACTOME ERYTHROPOIETIN ACTIVATES STAT5	7	5.55e-01	0.129000	6.90e-01
REACTOME RHO GTPASES ACTIVATE IQGAPS	31	5.55e-01	-0.061200	6.90e-01
REACTOME PP2A MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS	6	5.55e-01	0.139000	6.90e-01
REACTOME APOPTOTIC FACTOR MEDIATED RESPONSE	19	5.57e-01	0.077900	6.91e-01
REACTOME GLYCOGEN STORAGE DISEASES	15	5.59e-01	-0.087200	6.93e-01
REACTOME INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	28	5.60e-01	0.063700	6.93e-01
REACTOME GLUTATHIONE CONJUGATION	33	5.60e-01	0.058600	6.93e-01
REACTOME MET ACTIVATES PI3K AKT SIGNALING	6	5.61e-01	-0.137000	6.93e-01
REACTOME TRANSCRIPTIONAL REGULATION BY MECP2	60	5.61e-01	0.043400	6.93e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	14	5.61e-01	-0.089700	6.93e-01
REACTOME CHREBP ACTIVATES METABOLIC GENE EXPRESSION	8	5.63e-01	0.118000	6.95e-01
REACTOME DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A	5	5.64e-01	0.149000	6.96e-01
REACTOME HDL REMODELING	10	5.68e-01	-0.104000	7.00e-01
REACTOME EARLY SARS COV 2 INFECTION EVENTS	34	5.75e-01	-0.055600	7.06e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH CDK5	6	5.75e-01	0.132000	7.06e-01
REACTOME SIGNALING BY FLT3 ITD AND TKD MUTANTS	16	5.75e-01	0.081000	7.06e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1	20	5.75e-01	-0.072500	7.06e-01
REACTOME INTERLEUKIN 27 SIGNALING	11	5.75e-01	0.097600	7.07e-01
REACTOME INWARDLY RECTIFYING K CHANNELS	35	5.77e-01	-0.054500	7.08e-01
REACTOME PLASMA LIPOPROTEIN REMODELING	33	5.77e-01	-0.056000	7.08e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS	8	5.81e-01	0.113000	7.12e-01
REACTOME SLC TRANSPORTER DISORDERS	94	5.81e-01	0.032900	7.12e-01
REACTOME PHASE 3 RAPID REPOLARISATION	8	5.82e-01	-0.112000	7.12e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES	29	5.83e-01	-0.058800	7.13e-01
REACTOME COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING	32	5.84e-01	0.055900	7.14e-01
REACTOME METHIONINE SALVAGE PATHWAY	6	5.86e-01	0.128000	7.16e-01
REACTOME SYNTHESIS OF 15 EICOSATETRAENOIC ACID DERIVATIVES	6	5.88e-01	-0.128000	7.17e-01
REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS	17	5.90e-01	-0.075500	7.19e-01
REACTOME MULTIFUNCTIONAL ANION EXCHANGERS	9	5.91e-01	-0.104000	7.20e-01
REACTOME SIGNALING BY FGFR4 IN DISEASE	11	5.92e-01	0.093200	7.21e-01
REACTOME TELOMERE EXTENSION BY TELOMERASE	22	5.95e-01	0.065400	7.24e-01
REACTOME SIGNALING BY ERBB2 IN CANCER	26	5.96e-01	-0.060100	7.24e-01
REACTOME RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION	8	5.97e-01	0.108000	7.25e-01
REACTOME GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION	30	5.98e-01	-0.055700	7.25e-01
REACTOME EUKARYOTIC TRANSLATION ELONGATION	87	5.98e-01	0.032700	7.25e-01
REACTOME CRMPS IN SEMA3A SIGNALING	15	6.00e-01	-0.078200	7.27e-01
REACTOME INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL	14	6.01e-01	0.080800	7.27e-01
REACTOME PROSTANOID LIGAND RECEPTORS	9	6.02e-01	0.100000	7.29e-01
REACTOME SENSING OF DNA DOUBLE STRAND BREAKS	6	6.04e-01	0.122000	7.30e-01
REACTOME KINESINS	59	6.06e-01	-0.038900	7.32e-01
REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING	32	6.06e-01	-0.052600	7.32e-01
REACTOME SIGNALING BY RETINOIC ACID	41	6.09e-01	-0.046200	7.35e-01
REACTOME SIGNALING BY FGFR1	49	6.11e-01	-0.042000	7.37e-01
REACTOME HEME DEGRADATION	15	6.12e-01	-0.075700	7.37e-01
REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4	33	6.14e-01	0.050700	7.40e-01
REACTOME ALPHA OXIDATION OF PHYTANATE	6	6.17e-01	-0.118000	7.42e-01
REACTOME PD 1 SIGNALING	21	6.17e-01	0.063000	7.42e-01
REACTOME INTERLEUKIN 9 SIGNALING	7	6.21e-01	0.108000	7.46e-01
REACTOME GP1B IX V ACTIVATION SIGNALLING	11	6.22e-01	0.085900	7.46e-01
REACTOME DEFECTS IN VITAMIN AND COFACTOR METABOLISM	21	6.22e-01	0.062100	7.47e-01
REACTOME BH3 ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI APOPTOTIC BCL 2 MEMBERS	9	6.24e-01	0.094200	7.48e-01
REACTOME INDUCTION OF CELL CELL FUSION	12	6.25e-01	-0.081500	7.48e-01
REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	51	6.25e-01	0.039500	7.48e-01
REACTOME REGULATION OF BETA CELL DEVELOPMENT	41	6.25e-01	-0.044100	7.48e-01
REACTOME SIGNALING BY FGFR	85	6.26e-01	0.030600	7.48e-01
REACTOME PREGNENOLONE BIOSYNTHESIS	12	6.28e-01	0.080700	7.50e-01
REACTOME SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA PHE	6	6.30e-01	-0.114000	7.52e-01
REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE	71	6.31e-01	0.032900	7.53e-01
REACTOME TRANSPORT OF NUCLEOTIDE SUGARS	8	6.32e-01	0.097800	7.53e-01
REACTOME MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS	7	6.32e-01	-0.104000	7.53e-01
REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS	6	6.33e-01	-0.113000	7.53e-01
REACTOME EPHA MEDIATED GROWTH CONE COLLAPSE	29	6.33e-01	0.051200	7.53e-01
REACTOME SIGNALING BY WNT IN CANCER	32	6.34e-01	0.048600	7.54e-01
REACTOME PEXOPHAGY	11	6.37e-01	0.082100	7.57e-01
REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	38	6.38e-01	-0.044100	7.57e-01
REACTOME INTEGRATION OF PROVIRUS	9	6.39e-01	0.090300	7.58e-01
REACTOME MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS	17	6.43e-01	0.064900	7.61e-01
REACTOME BIOTIN TRANSPORT AND METABOLISM	10	6.43e-01	-0.084600	7.61e-01
REACTOME TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION	5	6.45e-01	-0.119000	7.61e-01
REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	69	6.45e-01	0.032100	7.61e-01
REACTOME INSULIN PROCESSING	24	6.45e-01	-0.054400	7.61e-01
REACTOME N GLYCAN TRIMMING AND ELONGATION IN THE CIS GOLGI	5	6.45e-01	0.119000	7.61e-01
REACTOME NEPHRIN FAMILY INTERACTIONS	22	6.45e-01	0.056700	7.61e-01
REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	23	6.47e-01	-0.055100	7.63e-01
REACTOME ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS	5	6.48e-01	-0.118000	7.63e-01
REACTOME PEROXISOMAL LIPID METABOLISM	28	6.52e-01	0.049200	7.67e-01
REACTOME SULFUR AMINO ACID METABOLISM	27	6.54e-01	0.049900	7.68e-01
REACTOME CLEC7A INFLAMMASOME PATHWAY	6	6.54e-01	-0.106000	7.68e-01
REACTOME NTRK2 ACTIVATES RAC1	5	6.54e-01	-0.116000	7.68e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	11	6.56e-01	0.077700	7.70e-01
REACTOME SHC1 EVENTS IN EGFR SIGNALING	14	6.57e-01	0.068600	7.71e-01
REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS	14	6.58e-01	-0.068300	7.71e-01
REACTOME GLYCEROPHOSPHOLIPID CATABOLISM	7	6.61e-01	-0.095800	7.74e-01
REACTOME SHC RELATED EVENTS TRIGGERED BY IGF1R	9	6.61e-01	0.084400	7.74e-01
REACTOME MITOCHONDRIAL UNCOUPLING	5	6.62e-01	-0.113000	7.75e-01
REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	15	6.64e-01	0.064800	7.75e-01
REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	17	6.64e-01	0.060900	7.75e-01
REACTOME ACTIVATION OF RAS IN B CELLS	5	6.66e-01	-0.111000	7.77e-01
REACTOME CHOLINE CATABOLISM	6	6.67e-01	-0.101000	7.78e-01
REACTOME SIGNALING BY HIPPO	19	6.68e-01	-0.056900	7.78e-01
REACTOME SIGNALING BY RECEPTOR TYROSINE KINASES	507	6.68e-01	0.011100	7.78e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY	19	6.68e-01	-0.056800	7.78e-01
REACTOME INTERLEUKIN 20 FAMILY SIGNALING	25	6.70e-01	0.049300	7.79e-01
REACTOME NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS	22	6.70e-01	0.052400	7.79e-01
REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	20	6.71e-01	0.054900	7.79e-01
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY	33	6.72e-01	0.042500	7.80e-01
REACTOME SYNTHESIS OF PE	13	6.77e-01	-0.066700	7.85e-01
REACTOME PEPTIDE HORMONE BIOSYNTHESIS	13	6.78e-01	0.066500	7.86e-01
REACTOME RUNX3 REGULATES YAP1 MEDIATED TRANSCRIPTION	8	6.79e-01	-0.084400	7.87e-01
REACTOME FLT3 SIGNALING BY CBL MUTANTS	7	6.80e-01	0.090100	7.87e-01
REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS	6	6.83e-01	-0.096200	7.90e-01
REACTOME FRUCTOSE CATABOLISM	5	6.84e-01	0.105000	7.91e-01
REACTOME ENOS ACTIVATION	11	6.85e-01	0.070700	7.91e-01
REACTOME ION TRANSPORT BY P TYPE ATPASES	51	6.86e-01	-0.032700	7.92e-01
REACTOME CHYLOMICRON CLEARANCE	5	6.88e-01	-0.104000	7.92e-01
REACTOME REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA	15	6.88e-01	0.059900	7.92e-01
REACTOME ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS	11	6.88e-01	0.069900	7.92e-01
REACTOME GABA B RECEPTOR ACTIVATION	43	6.89e-01	-0.035300	7.93e-01
REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	10	6.92e-01	0.072400	7.96e-01
REACTOME PLATELET HOMEOSTASIS	85	6.93e-01	0.024800	7.96e-01
REACTOME SYNTHESIS OF KETONE BODIES	8	6.94e-01	0.080200	7.97e-01
REACTOME CAMK IV MEDIATED PHOSPHORYLATION OF CREB	10	6.95e-01	0.071600	7.97e-01
REACTOME ACTIVATION OF NIMA KINASES NEK9 NEK6 NEK7	7	6.98e-01	0.084800	8.00e-01
REACTOME TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS	26	6.99e-01	-0.043800	8.01e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	34	7.01e-01	-0.038000	8.03e-01
REACTOME AZATHIOPRINE ADME	22	7.01e-01	0.047200	8.03e-01
REACTOME INTERFERON GAMMA SIGNALING	88	7.04e-01	-0.023500	8.04e-01
REACTOME PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING	5	7.04e-01	-0.098100	8.04e-01
REACTOME EPH EPHRIN MEDIATED REPULSION OF CELLS	50	7.06e-01	0.030900	8.06e-01
REACTOME DSCAM INTERACTIONS	11	7.07e-01	-0.065400	8.07e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING	25	7.07e-01	-0.043400	8.07e-01
REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	13	7.08e-01	-0.060000	8.07e-01
REACTOME G2 M DNA REPLICATION CHECKPOINT	5	7.09e-01	-0.096400	8.07e-01
REACTOME SODIUM COUPLED PHOSPHATE COTRANSPORTERS	5	7.10e-01	-0.095900	8.08e-01
REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	30	7.10e-01	-0.039200	8.08e-01
REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	14	7.11e-01	-0.057100	8.08e-01
REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	14	7.12e-01	-0.057000	8.08e-01
REACTOME PTK6 REGULATES CELL CYCLE	6	7.14e-01	-0.086400	8.10e-01
REACTOME DISINHIBITION OF SNARE FORMATION	5	7.17e-01	0.093600	8.13e-01
REACTOME HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR IN THE PRESENCE OF LIGAND	55	7.18e-01	0.028200	8.13e-01
REACTOME IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS	17	7.19e-01	-0.050500	8.14e-01
REACTOME WAX AND PLASMALOGEN BIOSYNTHESIS	5	7.19e-01	0.093000	8.14e-01
REACTOME TOXICITY OF BOTULINUM TOXIN TYPE D BOTD	5	7.22e-01	-0.091800	8.17e-01
REACTOME EARLY PHASE OF HIV LIFE CYCLE	14	7.23e-01	0.054700	8.17e-01
REACTOME UPTAKE AND ACTIONS OF BACTERIAL TOXINS	28	7.25e-01	0.038300	8.18e-01
REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R	52	7.26e-01	-0.028100	8.18e-01
REACTOME PROLONGED ERK ACTIVATION EVENTS	14	7.26e-01	0.054100	8.18e-01
REACTOME NEGATIVE REGULATION OF ACTIVITY OF TFAP2 AP 2 FAMILY TRANSCRIPTION FACTORS	10	7.26e-01	-0.064000	8.18e-01
REACTOME SIGNALING BY LEPTIN	11	7.28e-01	-0.060700	8.19e-01
REACTOME STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS	10	7.38e-01	0.061200	8.30e-01
REACTOME GROWTH HORMONE RECEPTOR SIGNALING	24	7.38e-01	-0.039400	8.30e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3	11	7.39e-01	-0.058100	8.30e-01
REACTOME MET ACTIVATES RAP1 AND RAC1	11	7.41e-01	0.057500	8.32e-01
REACTOME DRUG MEDIATED INHIBITION OF CDK4 CDK6 ACTIVITY	5	7.42e-01	-0.085200	8.32e-01
REACTOME COMMON PATHWAY OF FIBRIN CLOT FORMATION	21	7.43e-01	-0.041400	8.32e-01
REACTOME SIGNALING BY FGFR3	39	7.43e-01	0.030400	8.32e-01
REACTOME FORMATION OF AXIAL MESODERM	14	7.45e-01	0.050300	8.34e-01
REACTOME SIGNALING BY FGFR2 IN DISEASE	42	7.45e-01	0.029000	8.34e-01
REACTOME METHYLATION	14	7.46e-01	-0.050100	8.34e-01
REACTOME P75NTR REGULATES AXONOGENESIS	9	7.48e-01	-0.061700	8.37e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS	12	7.50e-01	0.053200	8.37e-01
REACTOME GASTRULATION	49	7.51e-01	-0.026200	8.37e-01
REACTOME INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION	21	7.51e-01	0.040000	8.37e-01
REACTOME TRANSPORT OF SMALL MOLECULES	697	7.51e-01	0.007050	8.37e-01
REACTOME SIGNALING BY FGFR4	40	7.52e-01	0.028900	8.38e-01
REACTOME GLUCAGON TYPE LIGAND RECEPTORS	32	7.56e-01	-0.031700	8.42e-01
REACTOME TYROSINE CATABOLISM	5	7.59e-01	0.079200	8.44e-01
REACTOME INTERLEUKIN 1 PROCESSING	9	7.62e-01	-0.058400	8.47e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH RAS	8	7.62e-01	0.061800	8.47e-01
REACTOME SUMOYLATION OF TRANSCRIPTION FACTORS	20	7.65e-01	0.038700	8.49e-01
REACTOME INTERLEUKIN 36 PATHWAY	7	7.66e-01	-0.064800	8.50e-01
REACTOME RUNX2 REGULATES BONE DEVELOPMENT	29	7.68e-01	-0.031700	8.50e-01
REACTOME DAG AND IP3 SIGNALING	40	7.68e-01	0.027000	8.50e-01
REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES	18	7.68e-01	-0.040100	8.50e-01
REACTOME DEPOLYMERISATION OF THE NUCLEAR LAMINA	14	7.69e-01	0.045300	8.50e-01
REACTOME COENZYME A BIOSYNTHESIS	8	7.69e-01	0.059900	8.50e-01
REACTOME PYROPTOSIS	27	7.69e-01	0.032600	8.50e-01
REACTOME DEFECTS IN BIOTIN BTN METABOLISM	8	7.70e-01	-0.059700	8.50e-01
REACTOME HYDROLYSIS OF LPC	9	7.72e-01	0.055900	8.51e-01
REACTOME FIBRONECTIN MATRIX FORMATION	6	7.74e-01	-0.067600	8.54e-01
REACTOME SYNTHESIS OF PI	5	7.76e-01	0.073600	8.54e-01
REACTOME PLATELET SENSITIZATION BY LDL	17	7.76e-01	0.039900	8.54e-01
REACTOME ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS	17	7.76e-01	-0.039800	8.54e-01
REACTOME INFLAMMASOMES	21	7.76e-01	0.035800	8.54e-01
REACTOME G PROTEIN MEDIATED EVENTS	53	7.78e-01	-0.022400	8.55e-01
REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	35	7.78e-01	0.027500	8.55e-01
REACTOME IRAK1 RECRUITS IKK COMPLEX	12	7.80e-01	0.046600	8.55e-01
REACTOME KETONE BODY METABOLISM	9	7.80e-01	0.053800	8.55e-01
REACTOME SMOOTH MUSCLE CONTRACTION	43	7.82e-01	-0.024400	8.57e-01
REACTOME SEMAPHORIN INTERACTIONS	61	7.87e-01	0.020000	8.62e-01
REACTOME SIGNALING BY NOTCH1 T 7 9 NOTCH1 M1580 K2555 TRANSLOCATION MUTANT	7	7.91e-01	0.057800	8.66e-01
REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION	26	7.93e-01	0.029800	8.67e-01
REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	13	7.96e-01	0.041400	8.70e-01
REACTOME RHOT1 GTPASE CYCLE	5	7.97e-01	0.066400	8.71e-01
REACTOME SYNTHESIS OF PC	27	7.98e-01	-0.028500	8.71e-01
REACTOME DAP12 INTERACTIONS	37	7.99e-01	0.024200	8.71e-01
REACTOME INTERLEUKIN 35 SIGNALLING	12	8.01e-01	0.042000	8.73e-01
REACTOME NICOTINATE METABOLISM	31	8.01e-01	0.026100	8.73e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING	5	8.02e-01	0.064900	8.73e-01
REACTOME SODIUM PROTON EXCHANGERS	7	8.02e-01	0.054600	8.73e-01
REACTOME ROBO RECEPTORS BIND AKAP5	9	8.06e-01	0.047200	8.77e-01
REACTOME TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7	12	8.07e-01	0.040700	8.77e-01
REACTOME FORMATION OF PARAXIAL MESODERM	22	8.08e-01	0.029900	8.78e-01
REACTOME EPHB MEDIATED FORWARD SIGNALING	41	8.11e-01	0.021600	8.80e-01
REACTOME RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA	7	8.11e-01	-0.052100	8.80e-01
REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF	17	8.12e-01	-0.033300	8.80e-01
REACTOME OAS ANTIVIRAL RESPONSE	8	8.12e-01	-0.048500	8.80e-01
REACTOME SIGNALING BY PTK6	54	8.13e-01	0.018600	8.80e-01
REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	23	8.13e-01	-0.028400	8.80e-01
REACTOME RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES TREGS	9	8.15e-01	-0.045100	8.81e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS	7	8.16e-01	0.050800	8.81e-01
REACTOME IRAK4 DEFICIENCY TLR2 4	17	8.17e-01	-0.032500	8.82e-01
REACTOME SURFACTANT METABOLISM	28	8.18e-01	-0.025100	8.83e-01
REACTOME PROTEIN REPAIR	6	8.20e-01	-0.053700	8.84e-01
REACTOME NUCLEOTIDE CATABOLISM	35	8.21e-01	-0.022000	8.85e-01
REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	111	8.24e-01	-0.012200	8.87e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH PI3K	6	8.25e-01	0.052000	8.88e-01
REACTOME METABOLISM OF VITAMINS AND COFACTORS	185	8.28e-01	0.009280	8.90e-01
REACTOME REGULATION OF BACH1 ACTIVITY	11	8.28e-01	0.037900	8.90e-01
REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB	5	8.30e-01	0.055400	8.91e-01
REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III	31	8.31e-01	0.022200	8.91e-01
REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	19	8.32e-01	0.028100	8.91e-01
REACTOME UPTAKE OF DIETARY COBALAMINS INTO ENTEROCYTES	9	8.32e-01	0.040800	8.91e-01
REACTOME IRF3 MEDIATED INDUCTION OF TYPE I IFN	13	8.32e-01	0.033900	8.91e-01
REACTOME LINOLEIC ACID LA METABOLISM	7	8.33e-01	0.046200	8.91e-01
REACTOME GDP FUCOSE BIOSYNTHESIS	6	8.33e-01	0.049600	8.91e-01
REACTOME RHOBTB3 ATPASE CYCLE	8	8.34e-01	0.042800	8.91e-01
REACTOME NRAGE SIGNALS DEATH THROUGH JNK	53	8.35e-01	-0.016500	8.92e-01
REACTOME ARMS MEDIATED ACTIVATION	7	8.39e-01	-0.044300	8.96e-01
REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	16	8.44e-01	0.028500	9.00e-01
REACTOME MYOCLONIC EPILEPSY OF LAFORA	9	8.44e-01	0.038000	9.00e-01
REACTOME FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS	8	8.45e-01	0.039800	9.01e-01
REACTOME RUNX2 REGULATES CHONDROCYTE MATURATION	5	8.47e-01	-0.049800	9.02e-01
REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	22	8.48e-01	-0.023600	9.02e-01
REACTOME SYNTHESIS OF PG	8	8.50e-01	0.038700	9.02e-01
REACTOME CD163 MEDIATING AN ANTI INFLAMMATORY RESPONSE	9	8.50e-01	-0.036400	9.02e-01
REACTOME RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION	6	8.51e-01	0.044400	9.02e-01
REACTOME STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES	16	8.51e-01	0.027200	9.02e-01
REACTOME STAT5 ACTIVATION	7	8.51e-01	0.041100	9.02e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING	5	8.52e-01	-0.048300	9.03e-01
REACTOME MISCELLANEOUS TRANSPORT AND BINDING EVENTS	24	8.54e-01	0.021700	9.04e-01
REACTOME DOWNREGULATION OF ERBB2 SIGNALING	29	8.55e-01	-0.019600	9.05e-01
REACTOME P2Y RECEPTORS	9	8.55e-01	0.035100	9.05e-01
REACTOME FLT3 SIGNALING THROUGH SRC FAMILY KINASES	6	8.56e-01	0.042800	9.05e-01
REACTOME SIGNALING BY MRAS COMPLEX MUTANTS	7	8.60e-01	0.038500	9.08e-01
REACTOME O LINKED GLYCOSYLATION OF MUCINS	61	8.60e-01	0.013000	9.08e-01
REACTOME MYOGENESIS	29	8.61e-01	-0.018800	9.09e-01
REACTOME PROPIONYL COA CATABOLISM	5	8.63e-01	0.044500	9.10e-01
REACTOME ATTACHMENT OF GPI ANCHOR TO UPAR	7	8.63e-01	0.037600	9.10e-01
REACTOME 2 LTR CIRCLE FORMATION	7	8.66e-01	0.037000	9.12e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH RAS	9	8.69e-01	-0.031700	9.15e-01
REACTOME VITAMIN D CALCIFEROL METABOLISM	12	8.72e-01	0.026900	9.17e-01
REACTOME INTEGRATION OF ENERGY METABOLISM	105	8.78e-01	-0.008660	9.23e-01
REACTOME THE NLRP3 INFLAMMASOME	16	8.80e-01	-0.021700	9.25e-01
REACTOME SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX	15	8.82e-01	-0.022100	9.26e-01
REACTOME MRNA EDITING C TO U CONVERSION	8	8.85e-01	0.029500	9.28e-01
REACTOME VLDL CLEARANCE	6	8.85e-01	-0.034000	9.28e-01
REACTOME SENSORY PERCEPTION OF SALTY TASTE	6	8.91e-01	0.032500	9.33e-01
REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING	33	8.94e-01	-0.013400	9.36e-01
REACTOME GERM LAYER FORMATION AT GASTRULATION	17	8.95e-01	0.018400	9.36e-01
REACTOME VLDL ASSEMBLY	5	8.95e-01	-0.034000	9.36e-01
REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE	11	8.97e-01	-0.022600	9.37e-01
REACTOME SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL	25	9.02e-01	-0.014200	9.42e-01
REACTOME MET ACTIVATES RAS SIGNALING	11	9.03e-01	0.021100	9.43e-01
REACTOME KERATAN SULFATE BIOSYNTHESIS	28	9.04e-01	0.013200	9.43e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS	14	9.04e-01	0.018500	9.43e-01
REACTOME IRS MEDIATED SIGNALLING	47	9.08e-01	-0.009720	9.46e-01
REACTOME SPERM MOTILITY AND TAXES	9	9.09e-01	-0.022000	9.46e-01
REACTOME VASOPRESSIN LIKE RECEPTORS	5	9.09e-01	-0.029400	9.46e-01
REACTOME INTERLEUKIN 10 SIGNALING	43	9.10e-01	0.009990	9.46e-01
REACTOME CA DEPENDENT EVENTS	36	9.12e-01	-0.010700	9.47e-01
REACTOME REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR	11	9.13e-01	-0.019000	9.48e-01
REACTOME APOPTOTIC EXECUTION PHASE	49	9.14e-01	0.008950	9.48e-01
REACTOME SCAVENGING BY CLASS F RECEPTORS	6	9.14e-01	-0.025300	9.49e-01
REACTOME MOLYBDENUM COFACTOR BIOSYNTHESIS	6	9.16e-01	-0.024800	9.50e-01
REACTOME RECYCLING PATHWAY OF L1	43	9.19e-01	-0.008920	9.52e-01
REACTOME METABOLISM OF INGESTED SEMET SEC MESEC INTO H2SE	7	9.21e-01	0.021700	9.53e-01
REACTOME DEFECTIVE LFNG CAUSES SCDO3	5	9.22e-01	0.025400	9.53e-01
REACTOME STAT3 NUCLEAR EVENTS DOWNSTREAM OF ALK SIGNALING	9	9.22e-01	0.018900	9.53e-01
REACTOME TYPE I HEMIDESMOSOME ASSEMBLY	11	9.23e-01	-0.016800	9.54e-01
REACTOME UREA CYCLE	9	9.25e-01	0.018100	9.55e-01
REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES	39	9.27e-01	0.008450	9.57e-01
REACTOME INSULIN RECEPTOR SIGNALLING CASCADE	53	9.30e-01	0.007010	9.59e-01
REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	28	9.37e-01	0.008690	9.65e-01
REACTOME HS GAG DEGRADATION	19	9.37e-01	-0.010500	9.65e-01
REACTOME CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND	9	9.38e-01	0.015000	9.65e-01
REACTOME BETA OXIDATION OF BUTANOYL COA TO ACETYL COA	5	9.38e-01	0.020100	9.65e-01
REACTOME INTERLEUKIN 21 SIGNALING	9	9.39e-01	-0.014800	9.65e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FYN	7	9.40e-01	-0.016400	9.66e-01
REACTOME HDL ASSEMBLY	8	9.41e-01	0.015100	9.66e-01
REACTOME EPHRIN SIGNALING	17	9.42e-01	-0.010300	9.66e-01
REACTOME LIPID PARTICLE ORGANIZATION	6	9.46e-01	0.016000	9.70e-01
REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	15	9.46e-01	0.010000	9.70e-01
REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	26	9.47e-01	-0.007480	9.70e-01
REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS	5	9.52e-01	0.015500	9.75e-01
REACTOME P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1	6	9.54e-01	-0.013500	9.76e-01
REACTOME TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE	10	9.55e-01	0.010300	9.76e-01
REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING	28	9.57e-01	-0.005950	9.76e-01
REACTOME SUMOYLATION OF INTRACELLULAR RECEPTORS	29	9.57e-01	0.005830	9.76e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE	20	9.57e-01	0.007010	9.76e-01
REACTOME INTERLEUKIN 6 FAMILY SIGNALING	24	9.58e-01	-0.006270	9.76e-01
REACTOME RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION	22	9.58e-01	-0.006490	9.76e-01
REACTOME NOSTRIN MEDIATED ENOS TRAFFICKING	5	9.59e-01	-0.013400	9.76e-01
REACTOME PKA ACTIVATION IN GLUCAGON SIGNALLING	17	9.59e-01	0.007190	9.76e-01
REACTOME ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS	10	9.65e-01	0.008020	9.82e-01
REACTOME PYRIMIDINE SALVAGE	10	9.69e-01	0.007080	9.85e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS	5	9.71e-01	-0.009290	9.87e-01
REACTOME EGFR INTERACTS WITH PHOSPHOLIPASE C GAMMA	9	9.74e-01	-0.006370	9.89e-01
REACTOME TRIGLYCERIDE METABOLISM	35	9.75e-01	-0.003110	9.89e-01
REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	14	9.76e-01	0.004590	9.90e-01
REACTOME IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN	5	9.79e-01	0.006840	9.91e-01
REACTOME PI3K AKT SIGNALING IN CANCER	103	9.80e-01	0.001420	9.91e-01
REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	19	9.81e-01	-0.003230	9.91e-01
REACTOME INACTIVATION OF CDC42 AND RAC1	8	9.81e-01	0.004900	9.91e-01
REACTOME EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION	27	9.81e-01	-0.002630	9.91e-01
REACTOME THYROXINE BIOSYNTHESIS	10	9.82e-01	-0.004200	9.91e-01
REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL	12	9.82e-01	0.003780	9.91e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST	14	9.82e-01	0.003490	9.91e-01
REACTOME PASSIVE TRANSPORT BY AQUAPORINS	13	9.82e-01	-0.003560	9.91e-01
REACTOME VITAMIN B2 RIBOFLAVIN METABOLISM	7	9.83e-01	0.004570	9.91e-01
REACTOME IRS ACTIVATION	5	9.84e-01	0.005250	9.91e-01
REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION	32	9.84e-01	-0.002010	9.91e-01
REACTOME PRE NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM	6	9.87e-01	0.003880	9.93e-01
REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	10	9.90e-01	0.002220	9.96e-01
REACTOME PTK6 EXPRESSION	5	9.92e-01	0.002730	9.96e-01
REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING	30	9.92e-01	-0.001110	9.96e-01
REACTOME NONCANONICAL ACTIVATION OF NOTCH3	8	9.92e-01	0.001990	9.96e-01
REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	16	9.94e-01	-0.001040	9.97e-01
REACTOME AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY	8	9.94e-01	-0.001440	9.97e-01
REACTOME REGULATED PROTEOLYSIS OF P75NTR	11	9.95e-01	-0.001040	9.97e-01
REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES	21	9.96e-01	0.000680	9.97e-01
REACTOME CROSS PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS PHAGOSOMES	6	9.98e-01	0.000636	9.98e-01
REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	23	9.98e-01	0.000261	9.98e-01

---

Detailed Gene set reports

REACTOME_METABOLISM_OF_RNA

REACTOME_METABOLISM_OF_RNA

	1313
set	REACTOME_METABOLISM_OF_RNA
setSize	675
pANOVA	1.1e-35
s.dist	0.281
p.adjustANOVA	1.8e-32

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SMG8	12132
UPF1	12077
TRMT44	12008
PRPF8	11964
CSNK1D	11871
POLR2J	11816
EIF4G1	11781
SUPT5H	11758
SMG1	11709
METTL14	11687
UTP14C	11680
SF1	11613
POLR2A	11407
POLR2E	11395
APOBEC2	11393
RPL32	11326
LSM4	11287
QTRT1	11266
ADAT1	11250
METTL3	11240

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SMG8	12132.0
UPF1	12077.0
TRMT44	12008.0
PRPF8	11964.0
CSNK1D	11871.0
POLR2J	11816.0
EIF4G1	11781.0
SUPT5H	11758.0
SMG1	11709.0
METTL14	11687.0
UTP14C	11680.0
SF1	11613.0
POLR2A	11407.0
POLR2E	11395.0
APOBEC2	11393.0
RPL32	11326.0
LSM4	11287.0
QTRT1	11266.0
ADAT1	11250.0
METTL3	11240.0
DHX37	11204.0
ZC3H11A	11183.0
WDR46	11171.0
DHX16	11089.0
PSMB4	11076.0
PPIH	11075.0
HNRNPM	11071.0
ADAT3	11056.0
NXF1	11039.0
EDC4	11024.0
SF3A3	11001.0
SKIC8	10984.0
CCDC12	10921.0
PSMD4	10893.0
GLE1	10891.0
RAE1	10890.0
GEMIN2	10880.0
PSMD13	10870.0
ERCC3	10866.0
CPSF6	10847.0
SYMPK	10822.0
EXOSC10	10801.0
PELP1	10778.0
NAT10	10774.0
RBM42	10732.0
PSMA2	10707.0
PPIL2	10648.0
SMG6	10639.0
BMS1	10591.0
PRPF38A	10583.0
RPL26	10573.0
PRPF18	10560.0
SUGP1	10559.0
EXOSC6	10554.0
POLDIP3	10549.0
WDR4	10542.0
ELAVL1	10495.0
ADAR	10484.0
APOBEC3C	10476.0
UPF3A	10472.0
NUP210	10455.0
PSMC6	10418.0
CPSF1	10403.0
FAM32A	10379.0
TRMT61B	10333.0
RBM5	10311.0
POLR2B	10306.0
TFIP11	10299.0
MAGOH	10284.0
EXOSC7	10219.0
IMP4	10208.0
UTP11	10200.0
SNRNP70	10173.0
NUP62	10167.0
EXOSC2	10153.0
EIF4A1	10151.0
WDR75	10098.0
SRRM2	10082.0
RPS9	10077.0
PARN	10060.0
NUP85	10023.0
CNOT3	9998.0
PSMD3	9979.0
CHERP	9969.0
SNRPD2	9957.0
PUF60	9935.0
NUP54	9855.0
GEMIN7	9853.0
PRPF19	9844.0
PSMD7	9804.0
AKT1	9802.0
XAB2	9792.0
RPL6	9786.0
DHX38	9776.0
CTU2	9752.0
MRM3	9739.0
PSMC4	9692.0
SNRPN	9640.0
ZMAT5	9637.0
PNO1	9622.0
RPL27A	9619.0
PSMD2	9598.0
U2AF2	9577.0
YJU2	9562.0
CPSF4	9551.0
URM1	9548.0
HNRNPC	9537.0
CSNK1E	9526.0
NUP88	9522.0
SNRPB	9514.0
CNOT1	9481.0
APOBEC3A	9465.0
PSMB5	9461.0
RPL19	9400.0
NUP133	9347.0
ELAC2	9315.0
RPL34	9275.0
PRKCD	9271.0
WBP4	9229.0
PRKRIP1	9222.0
FUS	9191.0
SNRPC	9188.0
DHX35	9177.0
PRPF6	9169.0
RPL14	9168.0
ALYREF	9167.0
WDR77	9157.0
RPL41	9118.0
DDX42	9106.0
XPOT	9078.0
MAGOHB	9064.0
LSM7	9054.0
SRRM1	9051.0
TRNT1	9043.0
RCL1	9011.0
PSMF1	9002.0
UTP3	8951.0
TRMT61A	8947.0
XPO1	8891.0
PRMT5	8850.0
NOC4L	8811.0
NSUN2	8782.0
C2orf49	8730.0
RPLP1	8728.0
SRRT	8722.0
U2SURP	8710.0
SMU1	8708.0
RIOK1	8699.0
ZFP36	8647.0
CNOT11	8644.0
DDX49	8606.0
SET	8592.0
GTF2F1	8571.0
PSMB7	8555.0
UTP15	8520.0
BCAS2	8514.0
CTU1	8513.0
NUP93	8494.0
PSMA4	8487.0
CCNH	8458.0
HBS1L	8452.0
POLR2H	8450.0
WDR33	8448.0
SMG5	8372.0
GEMIN5	8367.0
THOC5	8319.0
TSR1	8314.0
DDX20	8304.0
FBL	8273.0
TSEN2	8255.0
POM121	8233.0
CPSF2	8224.0
RPS15	8218.0
NUP50	8160.0
AAAS	8159.0
NUP58	8140.0
PAN2	8132.0
CLP1	8113.0
CNOT4	8107.0
PABPC1	8106.0
QTRT2	8039.0
RPL22	8037.0
SNRNP40	8019.0
SF3B3	8015.0
SKIC2	7998.0
DHX8	7997.0
PSMB1	7978.0
PSMA6	7971.0
HNRNPA2B1	7955.0
BUD31	7838.0
NUP98	7826.0
TFB1M	7771.0
ADARB1	7768.0
WDR12	7736.0
DHX15	7710.0
DUS2	7681.0
PSME2	7675.0
TRA2B	7660.0
PSMD1	7564.0
DIMT1	7516.0
RPS27A	7499.0
EBNA1BP2	7493.0
PSME1	7470.0
ZMAT2	7420.0
PAIP1	7412.0
PABPN1	7394.0
PPIL3	7267.0
RPP38	7255.0
LENG1	7253.0
RPS23	7245.0
RPS10	7219.0
PDCD11	7213.0
NCBP2	7200.0
UPF2	7186.0
ALKBH8	7159.0
CTNNBL1	7140.0
SNRNP200	7133.0
SF3A1	7119.0
SARNP	7085.0
HNRNPK	7040.0
PSMA3	7039.0
EXOSC5	7024.0
SF3B1	6993.0
PSMA1	6977.0
TRMT1	6976.0
NOL9	6961.0
PSMD6	6942.0
CRNKL1	6918.0
PCBP1	6906.0
TPRKB	6876.0
ETF1	6849.0
PPIE	6843.0
NOP14	6836.0
ISY1	6808.0
RPS20	6789.0
TEX10	6751.0
DCP1A	6718.0
NUP37	6708.0
SAP18	6685.0
PSMB3	6665.0
TRMT112	6663.0
PSMD11	6649.0
NSUN6	6636.0
THOC1	6626.0
NUDT21	6619.0
DDX39A	6564.0
RNGTT	6547.0
SRSF9	6509.0
HSPA8	6500.0
SF3B5	6491.0
TPR	6489.0
RPS27	6477.0
CNOT6	6456.0
RPP30	6434.0
DDX47	6429.0
PSMD12	6422.0
IMP3	6411.0
LSM5	6394.0
SNRNP35	6383.0
BOP1	6382.0
PSMB6	6370.0
RBM22	6330.0
NUP160	6322.0
PSMD5	6295.0
PSME3	6289.0
PCBP2	6238.0
WDR43	6229.0
RPS2	6180.0
RPS15A	6160.0
POP4	6127.0
CDK7	6114.0
DDX41	6050.0
CDC40	6019.0
RPS16	6017.0
DDX23	6002.0
FTSJ3	5996.0
RPL15	5994.0
RPP40	5952.0
PSMD9	5939.0
RPL11	5878.0
PRKCA	5835.0
ZNF473	5751.0
SEH1L	5744.0
SRSF4	5719.0
RBM8A	5667.0
PPP1R8	5660.0
SNUPN	5637.0
EDC3	5633.0
GTF2H3	5566.0
CWC22	5540.0
TYW5	5534.0
SLU7	5533.0
CACTIN	5479.0
NOL12	5415.0
ZFP36L1	5414.0
PSMB2	5390.0
UBC	5385.0
RPL35A	5375.0
NUP42	5371.0
DDX6	5360.0
SF3A2	5350.0
CNOT8	5346.0
RPPH1	5338.0
NSUN4	5316.0
TUT4	5292.0
TRMT10C	5266.0
HSPB1	5239.0
POLR2I	5214.0
PCF11	5207.0
MAPK14	5180.0
XRN1	5156.0
ERCC2	5135.0
DIS3	5080.0
RAN	5055.0
PSMA7	5054.0
MTERF4	5037.0
POLR2G	4982.0
UBL5	4931.0
GTPBP3	4908.0
OSGEP	4906.0
RANBP2	4890.0
HNRNPL	4884.0
BYSL	4878.0
SNIP1	4872.0
SEC13	4854.0
GTF2H1	4840.0
NUP214	4833.0
CNOT7	4797.0
UTP20	4784.0
DHX9	4737.0
EIF4B	4722.0
NOL11	4696.0
RPP14	4650.0
POP7	4640.0
CSTF2T	4633.0
POLR2F	4630.0
CWC25	4619.0
TRIT1	4606.0
PUS3	4536.0
PWP2	4533.0
BUD13	4481.0
RPL29	4480.0
PATL1	4458.0
THOC6	4417.0
KRR1	4414.0
RPS14	4403.0
RNPC3	4386.0
PSMA8	4378.0
SKIC3	4350.0
EMG1	4347.0
RPL28	4311.0
PPP2R1A	4310.0
SRSF6	4301.0
WDR70	4297.0
UTP25	4263.0
PRPF4	4243.0
GEMIN4	4198.0
FYTTD1	4186.0
NOL6	4168.0
GNL3	4164.0
RIOK3	4129.0
SNRPF	4099.0
PSMC2	4047.0
ZBTB8OS	3998.0
PNN	3997.0
SMG9	3991.0
MFAP1	3988.0
PSMB10	3971.0
THUMPD1	3966.0
SRSF11	3965.0
RPL31	3951.0
MRM1	3934.0
UTP18	3923.0
RPS3A	3917.0
SNRPE	3915.0
BUD23	3913.0
PES1	3869.0
LSM3	3863.0
IK	3839.0
WBP11	3834.0
HNRNPD	3781.0
HNRNPA1	3775.0
RRP36	3767.0
APOBEC1	3748.0
HNRNPU	3733.0
GTF2H5	3727.0
TNPO1	3709.0
CNOT6L	3685.0
FAM98B	3649.0
MTO1	3611.0
SNRPD3	3606.0
TRDMT1	3601.0
SMN1	3599.5
SMN2	3599.5
TBL3	3587.0
TCERG1	3568.0
HNRNPR	3555.0
LCMT2	3542.0
THADA	3528.0
RPL35	3510.0
THG1L	3503.0
PDCD7	3497.0
TNKS1BP1	3488.0
EIF4E	3463.0
RNMT	3418.0
TRMT11	3414.0
TRMT13	3399.0
PSMC3	3323.0
NUP107	3276.0
POLR2D	3258.0
MTREX	3213.0
RPL18	3205.0
SRSF1	3201.0
PRPF31	3198.0
RPL9	3178.0
RPS29	3176.0
RPS24	3174.0
PSMC1	3148.0
PSME4	3137.0
DCP2	3108.0
NDC1	3079.0
PSMC5	3065.0
PAN3	3064.0
MRM2	3056.0
POP1	3042.0
METTL1	3004.0
ANP32A	2973.0
PPIG	2920.0
PUS1	2856.0
SART1	2847.0
SNRNP48	2803.0
SMNDC1	2785.0
HSPA1A	2773.0
UTP4	2772.0
ACIN1	2707.0
SRSF5	2693.0
GSPT1	2677.0
NHP2	2655.0
PPIL1	2651.0
RPL21	2628.0
NOB1	2623.0
DDX39B	2621.0
SENP3	2597.0
GCFC2	2535.0
NUP188	2493.0
RPS3	2461.0
CPSF3	2435.0
EXOSC9	2431.0
CDKAL1	2407.0
NUP35	2378.0
RPL4	2357.0
RPS27L	2306.0
PSMB8	2300.0
CDC5L	2274.0
SNRPA1	2271.0
SRSF3	2267.0
THOC3	2255.0
WDR3	2245.0
TYW3	2212.0
RPL10A	2208.0
RPL12	2178.0
SNRPD1	2163.0
GTF2H4	2092.0
NSRP1	2065.0
EXOSC8	2045.0
POM121C	2036.0
LUC7L3	1957.0
CSTF3	1908.0
PSMD14	1903.0
SNRPG	1899.0
HNRNPF	1897.0
DCP1B	1886.0
CWC15	1872.0
RBM17	1870.0
TGS1	1787.0
RPL13A	1771.5
DDX5	1755.0
PSMB11	1723.0
SF3B2	1722.0
NCL	1627.0
SDE2	1612.0
DDX46	1605.0
TRMU	1601.0
RBM39	1598.0
PRPF3	1597.0
RBM25	1564.0
FAU	1541.0
PPWD1	1484.0
RPL36	1472.0
THOC7	1471.0
GAR1	1431.0
DDX1	1418.0
PTBP1	1402.0
PRPF40A	1393.0
TSEN54	1389.0
CLNS1A	1366.0
SNRNP25	1361.0
CASC3	1351.0
CNOT10	1347.0
RPS21	1329.0
U2AF1L4	1290.0
MPHOSPH10	1288.0
SRSF12	1262.0
CNOT9	1258.0
YWHAZ	1179.0
RPL37	1116.0
ZNF830	1115.0
NOP56	1100.0
RRP7A	1084.0
RPP25	1073.0
TSEN15	1043.0
RPS18	992.0
LSM6	951.0
CNOT2	924.0
CPSF7	901.0
RPL30	897.0
NOP2	837.0
RPP21	802.0
C9orf78	789.0
PUS7	720.0
TSEN34	707.0
NOP58	680.0
DDX21	657.0
TRMT6	631.0
EXOSC1	625.0
PNRC2	576.0
NUP43	561.0
RPS6	524.0
APOBEC3H	475.0
RPS7	463.0
HNRNPA3	428.0
PPIL4	417.0
LSM8	333.0
NUP205	331.0
PAPOLA	320.0
CSTF1	299.0
CCAR1	199.0
SMG7	188.0
FCF1	187.0
YWHAB	170.0
LSM2	163.0
EIF4A3	121.0
CWC27	91.0
AQR	42.0
XRN2	-30.0
NCBP1	-175.0
TXNL4A	-184.0
RPL18A	-240.0
RPL23	-261.0
RPL27	-270.0
CHTOP	-280.0
HEATR1	-315.0
DCAF13	-321.0
ISG20L2	-322.0
MNAT1	-336.0
TP53RK	-391.0
RPLP0	-487.0
CWF19L2	-492.0
SNRPB2	-564.0
HNRNPH1	-594.0
WDR36	-606.0
EIF4A2	-739.0
EFTUD2	-937.0
LTV1	-1004.0
ZCRB1	-1100.0
RTCB	-1103.0
PRORP	-1114.0
SNRPA	-1139.0
EXOSC4	-1198.0
LSM10	-1225.0
YBX1	-1287.0
LSM11	-1356.0
NOP10	-1391.0
GTF2F2	-1392.0
SRSF7	-1396.0
RIOK2	-1426.0
SNU13	-1463.0
DNAJC8	-1502.0
RPS13	-1554.0
NXT1	-1557.0
GPATCH1	-1626.0
PPP2R2A	-1648.0
POLR2L	-1678.0
USP39	-1751.0
WDR18	-1790.0
TRMT10A	-1906.0
EXOSC3	-1962.0
RBM7	-1970.0
MAPKAPK2	-2022.0
PPP2CA	-2084.0
LSM1	-2113.0
SF3B4	-2190.0
RPL26L1	-2195.0
RPSA	-2216.0
UBA52	-2237.0
MPHOSPH6	-2244.0
POP5	-2273.0
RPL7	-2286.0
UBB	-2335.0
RPS5	-2392.0
WTAP	-2436.0
PHAX	-2500.0
NUP153	-2541.0
TYW1	-2556.0
TSR3	-2567.0
RPS28	-2610.0
RPL36AL	-2643.5
RTRAF	-2697.0
SYF2	-2735.0
SRSF10	-2873.0
RPS12	-2916.0
ERI1	-2929.0
PSMB9	-2938.0
SRSF2	-3015.0
NIP7	-3085.0
TRMT9B	-3103.0
SLBP	-3174.0
GEMIN6	-3184.0
NUP155	-3213.0
TNFSF13	-3307.0
RPL22L1	-3311.0
EPRS1	-3323.0
FIP1L1	-3399.0
RBM28	-3446.0
RPL39L	-3504.0
DDX52	-3605.0
RPL5	-3668.0
IGF2BP1	-3680.0
PLRG1	-3701.0
MAPK11	-3828.0
POLR2K	-3852.0
RNPS1	-3954.0
RPS11	-4060.0
UTP6	-4097.0
TRMT12	-4103.0
RPL3L	-4134.0
PRCC	-4201.0
RPS19	-4241.0
TUT7	-4245.0
SNW1	-4266.0
PSMA5	-4331.0
RPL17	-4430.0
RPL3	-4491.0
RPLP2	-4579.0
TRMT5	-4627.0
RPL7A	-4734.0
PHF5A	-4818.0
C1D	-4932.0
RPL23A	-4959.0
PSMD8	-5050.0
IGF2BP2	-5168.0
RPL10L	-5285.0
ADAT2	-5425.0
RPL24	-5518.0
IGF2BP3	-5557.0
DCPS	-5615.0
KHSRP	-5893.0
NT5C3B	-5896.0
POLR2C	-6018.0
APOBEC3B	-6032.0
SF3B6	-6121.0
SNRNP27	-6233.0
RRP9	-6261.0
RPL38	-6279.0
RPL13	-6322.0
RPL8	-6372.0
RPS8	-6455.0
RPS25	-6687.0
RPL37A	-7080.0
RRP1	-7254.0
SEM1	-7461.0
APOBEC4	-7960.0
SRSF8	-8657.0
RPS26	-8718.0
A1CF	-8970.0

---

REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

	1161
set	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION
setSize	1336
pANOVA	1.24e-30
s.dist	0.187
p.adjustANOVA	1.02e-27

Top enriched genes

Top 20 genes

GeneID	Gene Rank
AGRP	12166
ZNF738	12062
BRD1	12058
ZNF717	12036
INTS5	12013
ZSCAN25	11962
ZNF679	11841
PDPK1	11829
POLR2J	11816
AXIN1	11805
LAMTOR3	11769
SUPT5H	11758
CREBBP	11715
ZNF468	11693
BRPF1	11679
RUNX3	11675
ZNF383	11632
TCF3	11610
ZNF786	11596
CEBPB	11589

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
AGRP	12166.0
ZNF738	12062.0
BRD1	12058.0
ZNF717	12036.0
INTS5	12013.0
ZSCAN25	11962.0
ZNF679	11841.0
PDPK1	11829.0
POLR2J	11816.0
AXIN1	11805.0
LAMTOR3	11769.0
SUPT5H	11758.0
CREBBP	11715.0
ZNF468	11693.0
BRPF1	11679.0
RUNX3	11675.0
ZNF383	11632.0
TCF3	11610.0
ZNF786	11596.0
CEBPB	11589.0
ZNF589	11572.0
NR1H2	11561.0
NR0B2	11553.0
MED25	11528.0
H2BC15	11524.0
ZNF597	11520.0
E2F6	11512.0
TFDP1	11506.0
KMT2D	11499.0
SMARCA4	11496.0
ZNF724	11493.0
TCF7	11471.0
CGB5	11457.0
H4C5	11447.0
ZNF382	11444.0
SMARCB1	11429.0
POLR2A	11407.0
POLR2E	11395.0
ZNF716	11378.0
ZNF394	11358.0
AGO1	11345.0
RNF34	11329.0
H2BC6	11322.0
ZNF626	11311.0
FZR1	11268.0
ZNF529	11225.0
SMARCC2	11212.0
KMT2B	11211.0
ZC3H11A	11183.0
MED4	11166.0
RNU4ATAC	11157.0
MLLT1	11156.0
TGFB1	11148.0
UBE2I	11138.0
ZNF506	11124.0
PSMB4	11076.0
GATAD2A	11072.0
NCOR2	11049.0
HDAC4	11016.0
MTOR	11011.0
RTF1	11007.0
MED8	11003.0
BANP	11002.0
PPP2R1B	10998.0
SKIC8	10984.0
MED10	10955.0
USP7	10931.0
SKI	10917.0
PSMD4	10893.0
CHD3	10888.0
ZNF750	10872.0
PSMD13	10870.0
H2AZ1	10867.0
ERCC3	10866.0
RAD9A	10850.0
CPSF6	10847.0
SETD1A	10831.0
SYMPK	10822.0
PIP4P1	10816.0
ZNF493	10811.0
RETN	10807.0
RARG	10787.0
DAXX	10716.0
SLC2A3	10708.0
PSMA2	10707.0
PMS2	10704.0
GTF2A1	10680.0
YWHAE	10677.0
RPA1	10676.0
ZNF710	10651.0
ARID1A	10632.0
NR4A3	10627.0
PARP1	10610.0
YY1	10609.0
GPX2	10608.0
MAML1	10607.0
INTS11	10606.0
ZNF561	10592.0
NOTCH1	10585.0
POLDIP3	10549.0
ZNF560	10545.0
PRR5	10543.0
ELOB	10535.0
PPARD	10524.0
CAMK2G	10508.0
ZNF45	10477.0
CDC23	10475.0
COX16	10473.0
ANAPC15	10466.0
LGALS3	10461.0
ZNF737	10441.0
ZNF713	10433.0
MED24	10431.0
ZNF282	10419.0
PSMC6	10418.0
PIP4K2A	10408.0
CPSF1	10403.0
WWP1	10374.0
TRIM33	10347.0
ZNF213	10336.0
ICE1	10324.0
POLR2B	10306.0
ZNF775	10293.0
MED6	10290.0
MAGOH	10284.0
ZNF570	10252.0
EPC1	10250.0
NCOR1	10213.0
INTS8	10204.0
E2F4	10203.0
ZNF485	10197.0
TAF4	10162.0
ZNF337	10139.0
MED1	10131.0
NELFCD	10110.0
RMI2	10057.0
COX6B1	10052.0
ZNF510	10039.0
CHD4	10037.0
ZNF556	10035.0
SETD1B	10015.0
TACO1	10013.0
CNOT3	9998.0
KMT2C	9984.0
PSMD3	9979.0
ZNF233	9914.0
CDC25C	9899.0
BID	9888.0
ZNF274	9883.0
NR2C2	9867.0
RMI1	9852.0
ZNF500	9849.0
TAF13	9847.0
SP7	9812.0
TNFRSF10D	9810.0
PSMD7	9804.0
AKT1	9802.0
COX14	9790.0
DDIT3	9785.0
CDK5R1	9783.0
PTPN4	9777.0
DHX38	9776.0
COX8A	9775.0
PRKAB1	9761.0
GADD45A	9743.0
ZNF398	9736.0
IL2	9735.0
NELFB	9731.0
AGO2	9717.0
PLK3	9710.0
PSMC4	9692.0
ZNF689	9688.0
RPTOR	9678.0
ZNF564	9666.0
ARID3A	9655.0
ANAPC1	9651.0
ZNF530	9649.0
SRC	9630.0
SMAD7	9613.0
ZNF696	9603.0
SMURF2	9601.0
PSMD2	9598.0
WDR5	9587.0
LAMTOR1	9581.0
U2AF2	9577.0
ZNF426	9575.0
CDK13	9570.0
YWHAG	9563.0
CPSF4	9551.0
CENPJ	9539.0
ZNF563	9536.0
E2F8	9534.0
KCTD15	9533.0
SNRPB	9514.0
NFYA	9507.0
LMO2	9499.0
CNOT1	9481.0
H2AC4	9477.0
TNFRSF10B	9467.0
PSMB5	9461.0
MGA	9458.0
RFFL	9452.0
CDC73	9451.0
RABGGTA	9443.0
FANCI	9428.0
SMYD2	9416.0
TNRC6C	9415.0
CASP2	9410.0
ZNF726	9394.0
EP300	9390.0
CDKN1B	9381.0
ZNF721	9372.0
ZNF600	9357.0
ELF2	9352.0
ZNF253	9337.0
ZKSCAN1	9328.0
ZNF92	9303.0
KAT2B	9295.0
SREBF1	9257.0
NDUFA4	9254.0
HES1	9251.0
ZNF420	9246.0
IL2RA	9186.0
KMT5A	9179.0
ALYREF	9167.0
ZNF100	9164.0
APAF1	9150.0
CDK12	9144.0
DDIT4	9141.0
ZNF569	9128.0
CALM1	9105.0
ZNF267	9091.0
H4C6	9077.0
MAGOHB	9064.0
SRRM1	9051.0
STK11	9027.0
PRKACA	9014.0
PSMF1	9002.0
ELF1	8952.0
LAMTOR4	8940.0
GP1BA	8928.0
PHF20	8925.0
MAX	8923.0
FURIN	8913.0
H3C11	8908.0
H2BC10	8901.0
ZNF547	8898.0
XPO1	8891.0
ZNF668	8875.0
ZKSCAN3	8855.0
PRMT5	8850.0
KMT2A	8841.0
PF4	8810.0
ZNF443	8800.0
TCEA1	8796.0
KAT6A	8784.0
MED15	8773.0
NELFE	8758.0
ZNF549	8754.0
ZNF582	8752.0
TFDP2	8744.0
PPARA	8725.0
SRRT	8722.0
ZNF484	8719.0
CREB1	8716.0
ZNF227	8701.0
ZNF211	8694.0
ZNF14	8677.0
ZKSCAN5	8676.0
ARID1B	8673.0
MAP2K6	8671.0
CCNT1	8657.0
CNOT11	8644.0
NELFA	8636.0
SNAPC3	8627.0
COX19	8609.0
CASP10	8604.0
ITGAL	8602.0
DEK	8586.0
GTF2F1	8571.0
PSMB7	8555.0
ZNF777	8546.0
ZNF627	8527.0
KAT2A	8511.0
PSMA4	8487.0
ZNF264	8475.0
CCNK	8473.0
PTPN1	8463.0
CCNH	8458.0
INTS1	8453.0
POLR2H	8450.0
WDR33	8448.0
RNU12	8441.0
ZNF2	8439.0
SMURF1	8435.0
RFC2	8432.0
AKT2	8422.0
ACTL6A	8382.0
ERBB2	8378.0
RBL2	8353.0
ZNF615	8337.0
CARM1	8334.0
YES1	8329.0
MED23	8325.0
EHMT1	8321.0
THOC5	8319.0
NFATC2	8308.0
PIDD1	8298.0
H2AC6	8277.0
ZNF37A	8261.0
ZNF662	8253.0
CASP6	8250.0
H4C11	8241.0
PML	8234.0
CPSF2	8224.0
INTS9	8208.0
EAF2	8181.0
NR2F6	8179.0
PLAGL1	8171.0
HDAC5	8138.0
TGIF2	8119.0
H4C13	8117.0
CLP1	8113.0
CNOT4	8107.0
SMARCC1	8102.0
TOPBP1	8095.0
ZNF550	8088.0
ANAPC16	8064.0
ZNF324	8043.0
H4C1	8017.0
GLS	7990.0
PSMB1	7978.0
PSMA6	7971.0
DNA2	7894.0
ZNF585A	7878.0
TAF3	7849.0
ZNF138	7840.0
GSR	7831.0
ZNF620	7820.0
ZNF708	7813.0
ZNF565	7788.0
RHEB	7765.0
BLM	7764.0
CSNK2A1	7758.0
ZNF26	7740.0
H2AC8	7728.0
PIN1	7723.0
ZNF286A	7719.0
TAF2	7715.0
MED27	7703.0
ZNF655	7700.0
PRKAB2	7695.0
NOC2L	7694.0
ZNF350	7693.0
PSME2	7675.0
ANAPC4	7652.0
TNRC6A	7634.0
MBD3	7608.0
RBM14	7592.0
ZNF670	7572.0
PSMD1	7564.0
ZC3H8	7560.0
ANAPC5	7558.0
CDK5	7545.0
H2BC4	7539.0
MAPK3	7526.0
ZNF736	7503.0
RPS27A	7499.0
LBR	7494.0
ZNF735	7477.0
PSME1	7470.0
MED13	7467.0
TXNIP	7462.0
TAF4B	7454.0
FANCD2	7450.0
GTF2E1	7447.0
RBBP8	7402.0
H3C1	7395.0
PABPN1	7394.0
ZNF616	7362.0
ELL	7361.0
ATXN3	7354.0
CAT	7326.0
ZNF425	7315.0
KMT2E	7299.0
INTS13	7281.0
ZFPM1	7275.0
THRA	7231.0
H2BC9	7228.5
H3C7	7228.5
EHMT2	7223.0
NCBP2	7200.0
CDC27	7198.0
GPI	7195.0
ZNF599	7187.0
NDRG1	7185.0
PRELID3A	7149.0
COX5A	7138.0
ZNF740	7116.0
INTS3	7086.0
SARNP	7085.0
ZNF791	7082.0
H4C8	7058.0
PSMA3	7039.0
ELL2	7008.0
SNAPC4	6980.0
PSMA1	6977.0
ZNF619	6951.0
SMARCD2	6948.0
PSMD6	6942.0
TMEM219	6938.0
CBX3	6860.0
BLK	6844.0
ZNF226	6827.0
NR2C1	6783.0
GPS2	6767.0
CDC16	6748.0
PRKCB	6744.0
FOXO3	6739.0
ZNF331	6721.0
ZNF746	6717.0
ZNF254	6682.0
PSMB3	6665.0
PHC2	6654.0
H3C10	6652.0
PSMD11	6649.0
CITED4	6647.0
THOC1	6626.0
NUDT21	6619.0
ESR2	6594.0
ZNF691	6565.0
DDX39A	6564.0
HTT	6559.0
SUPT16H	6552.0
RNGTT	6547.0
ZNF461	6531.0
POU2F2	6529.0
SRSF9	6509.0
MLH1	6506.0
PINK1	6493.0
INTS4	6478.0
ZIM2	6476.0
JAG1	6471.0
ZNF385A	6469.0
CNOT6	6456.0
ZNF74	6452.0
NPAS4	6431.0
INTS2	6427.0
MSH2	6423.0
PSMD12	6422.0
DYRK2	6420.0
HIPK2	6408.0
ZNF436	6405.0
TAF1L	6402.0
TSC2	6400.0
TEAD4	6396.0
ZNF624	6393.0
PSMB6	6370.0
COX6C	6367.0
TP53INP1	6350.0
ANAPC10	6338.0
H2BC8	6334.0
SURF1	6325.0
PSMD5	6295.0
PSME3	6289.0
PIP4K2B	6253.0
H2BC12	6220.0
NR1D1	6211.0
MAPKAP1	6204.0
ZFP69B	6189.0
RING1	6185.0
ZNF33A	6175.0
ABL1	6174.0
NR1D2	6172.0
ZNF460	6171.0
STAT1	6170.0
IL6	6166.0
MDM4	6157.0
CCNG2	6150.0
TNRC6B	6144.0
MYC	6135.0
ZNF688	6124.0
JMY	6120.0
CDK7	6114.0
CBX4	6103.0
ZNF714	6088.0
MED26	6084.0
LDB1	6071.0
CGB8	6065.0
HDAC1	6062.0
INTS12	6021.0
RELA	6020.0
CDC40	6019.0
YWHAQ	5997.0
CITED2	5977.0
RBL1	5966.0
SMARCA2	5954.0
CSNK2A2	5953.0
PSMD9	5939.0
HEY1	5927.0
ZNF528	5919.0
H3C4	5911.0
ZFP69	5887.0
PRKAA1	5866.0
ZNF667	5857.0
ATAD2	5840.0
BRD2	5832.0
MAPK1	5826.0
GSK3B	5797.0
ANAPC11	5794.0
MEAF6	5790.0
CTSK	5782.0
SMAD2	5768.0
ZNF317	5759.0
ZNF473	5751.0
RBPJ	5745.0
SRSF4	5719.0
SIN3A	5710.0
ZNF439	5708.0
CDC26	5692.0
TIGAR	5684.0
ZNF764	5676.0
RBM8A	5667.0
ZNF613	5665.0
ZNF430	5647.0
JUN	5629.0
TBP	5601.0
ZNF573	5599.0
SUZ12	5592.0
TWIST1	5588.0
PRDX5	5581.0
GTF2H3	5566.0
CSNK2B	5559.0
ZNF223	5548.0
SLU7	5533.0
ZKSCAN8	5525.0
SSU72	5520.0
PBRM1	5510.0
TOP3A	5504.0
TGIF1	5496.0
ZNF101	5463.0
SIN3B	5452.0
NR1I2	5443.0
ZNF490	5439.0
ELOA	5436.0
ZNF607	5428.0
ZNF567	5420.0
HDAC3	5406.0
MED16	5401.0
PSMB2	5390.0
UBC	5385.0
NR2E3	5354.0
CNOT8	5346.0
PRKAG2	5343.0
ZNF28	5329.0
BMI1	5313.0
ZNF441	5306.0
IGFBP3	5303.0
H4C3	5297.0
ESRRA	5295.0
ZNF77	5264.0
AURKA	5237.0
POLR2I	5214.0
CBX8	5208.0
PCF11	5207.0
ZNF136	5200.0
RPA2	5194.0
MAPK14	5180.0
ZNF304	5174.0
ZNF778	5162.0
H2AJ	5141.0
ZFP90	5138.0
ERCC2	5135.0
GPAM	5127.0
PTPN11	5117.0
ZNF699	5110.0
ZNF701	5105.0
ABCA6	5096.0
CCND3	5083.0
MDM2	5073.0
RFC5	5072.0
ZNF257	5070.0
PSMA7	5054.0
ITCH	5050.0
PPP2R5C	5016.0
KAT5	5000.0
ZNF749	4989.0
POLR2G	4982.0
CHEK1	4981.0
ICE2	4946.0
RXRA	4895.0
ZNF641	4894.0
INTS10	4843.0
NFYC	4842.0
GTF2H1	4840.0
ZNF324B	4836.0
ZNF3	4808.0
CNOT7	4797.0
TSC1	4794.0
DGCR8	4785.0
PHC3	4783.0
ZNF496	4748.0
TAF7	4746.0
CTLA4	4724.0
DDB2	4656.0
ZNF681	4635.0
CSTF2T	4633.0
POLR2F	4630.0
POMC	4603.0
NFYB	4583.0
ZNF700	4557.0
ZNF230	4543.0
SCMH1	4529.0
ZNF143	4524.0
RFC4	4504.0
MED17	4482.0
FBXW7	4447.0
THOC6	4417.0
ZNF354A	4391.0
ZNF611	4388.0
PSMA8	4378.0
AIFM2	4373.0
RUNX2	4363.0
PPP2R1A	4310.0
SRSF6	4301.0
LEF1	4299.0
ZNF678	4287.0
UBE2D3	4277.0
BMAL1	4261.0
RNU11	4255.0
GATA3	4254.0
ZFP2	4225.0
TNFRSF10A	4205.0
FYTTD1	4186.0
PPARGC1A	4184.0
PRKCQ	4181.0
CBX5	4150.0
KRBA1	4137.0
SNRPF	4099.0
ARNT	4094.0
POU4F1	4082.0
PTEN	4078.0
SKIL	4077.0
BRPF3	4071.0
CYCS	4068.0
RPRD2	4057.0
PSMC2	4047.0
ITGA5	4045.0
ZNF189	4043.0
WRN	4033.0
CUL1	4015.0
SOCS4	4014.0
TAF15	4012.0
H4C2	3987.0
PSMB10	3971.0
SRSF11	3965.0
ZNF664	3963.0
GATAD2B	3962.0
SNRPE	3915.0
ZNF133	3897.0
RBBP4	3878.0
YWHAH	3875.0
MOBP	3851.0
ZNF671	3847.0
INTS6	3844.0
BRIP1	3816.0
PHC1	3804.0
BTG1	3797.0
ANAPC7	3782.0
PAF1	3755.0
TCF12	3739.0
GTF2H5	3727.0
SKP1	3705.0
CNOT6L	3685.0
HIPK1	3677.0
ZNF566	3675.0
HDAC10	3671.0
ZNF250	3613.0
SNRPD3	3606.0
H4C4	3596.0
ZNF33B	3591.0
SOX9	3580.0
ZNF160	3573.0
MYB	3572.0
MRE11	3571.0
MAPKAPK5	3566.0
L3MBTL2	3551.0
ZFP14	3545.0
ZNF605	3523.0
H3C8	3521.0
TP53	3499.0
RAD51D	3495.0
TNKS1BP1	3488.0
RNF111	3481.0
UBE2E1	3470.0
ZNF18	3458.0
MTA2	3431.0
ZNF551	3429.0
AGO3	3420.0
RNMT	3418.0
ZNF169	3417.0
MED7	3403.0
SMAD3	3402.0
H2AC20	3382.0
PRMT1	3343.0
PMAIP1	3340.0
ZNF707	3329.0
PSMC3	3323.0
POLR2D	3258.0
SRSF1	3201.0
ZNF248	3199.0
ZNF658	3196.0
RPAP2	3171.0
TAF8	3164.0
ZNF19	3150.0
BRD7	3149.0
PSMC1	3148.0
RPA3	3146.0
PSME4	3137.0
COX7A2L	3104.0
FOXG1	3087.0
PSMC5	3065.0
BCL6	3059.0
H3-3B	3055.0
ZNF785	3053.0
HIVEP3	3052.0
COX4I1	3049.0
LRPPRC	3047.0
ZNF486	3024.0
ZNF431	3020.0
FBXO32	3005.0
ZNF268	2993.0
ZNF584	2956.0
H2AC18	2954.5
H2AC19	2954.5
ZNF839	2930.0
MYBL2	2911.0
TRPC3	2900.0
INTS7	2893.0
IL3	2873.0
TCF7L2	2859.0
RYBP	2853.0
ELOC	2833.0
GTF2B	2820.0
CBX2	2819.0
SMARCD1	2809.0
KCTD6	2802.0
H2AC7	2792.5
H2BC7	2792.5
BRCA1	2780.0
RRM2	2760.0
HDAC7	2721.0
H2BC21	2718.0
GTF2E2	2708.0
CAV1	2698.0
SRSF5	2693.0
RFC3	2692.0
TTC5	2683.0
RPRD1B	2676.0
ZNF235	2675.0
ZNF200	2660.0
ZNF555	2630.0
DDX39B	2621.0
NRBF2	2605.0
PRKAG1	2584.0
ZFP30	2569.0
PPM1D	2503.0
ZNF71	2467.0
COX11	2459.0
GPRIN1	2453.0
GATA2	2450.0
ZNF225	2437.0
CPSF3	2435.0
ZNF571	2429.0
SRF	2415.0
SGK1	2406.0
CDKN1A	2387.0
NR1I3	2377.0
ZNF433	2369.0
COX6A1	2351.0
PSMB8	2300.0
ZNF222	2289.0
CDK4	2268.0
SRSF3	2267.0
H3-3A	2262.0
THOC3	2255.0
CTNNB1	2250.0
USP2	2228.0
PRDX1	2226.0
BCL2L11	2213.0
CTDP1	2201.0
CDK8	2180.0
ATR	2151.0
ZNF446	2149.0
RAD9B	2147.0
ATM	2137.0
CCNB1	2131.0
H2BC5	2100.0
ZNF205	2099.0
GTF2H4	2092.0
ZSCAN32	2088.0
PCBP4	2069.0
RRAGA	2063.0
TXN	2053.0
TXNRD1	2049.0
TP53AIP1	2047.0
ZNF680	2031.0
ING5	2015.0
ZNF544	2014.0
KDM5B	2000.0
COX5B	1997.0
ZNF347	1994.0
ZNF416	1992.0
E2F7	1968.0
ZNF747	1967.0
BTG2	1962.0
TAF6	1945.0
KRBOX5	1915.0
CSTF3	1908.0
CHEK2	1906.0
PSMD14	1903.0
SNRPG	1899.0
UBE2S	1865.0
H2BC17	1857.0
TAF12	1849.0
ESR1	1837.0
H2BC13	1834.0
H3C2	1828.0
NR2C2AP	1822.0
ZNF311	1817.0
SESN1	1738.0
TAF5	1730.0
PSMB11	1723.0
ZNF554	1699.0
GLS2	1688.0
RXRB	1683.0
SUPT6H	1665.0
MLLT3	1626.0
ZNF224	1615.0
MED30	1584.0
PRDM1	1581.0
PPP1R13B	1543.0
ARID2	1517.0
ZNF419	1501.0
ZNF559	1490.0
SIRT1	1473.0
THOC7	1471.0
ELL3	1465.0
CDK1	1360.0
RB1	1359.0
CASC3	1351.0
CNOT10	1347.0
GTF2A2	1343.0
FASLG	1308.0
U2AF1L4	1290.0
H2BC11	1286.0
ZNF782	1269.0
ZNF23	1268.0
CNOT9	1258.0
ZNF546	1244.0
RICTOR	1224.0
STEAP3	1196.0
ZNF12	1190.0
YWHAZ	1179.0
MOV10	1158.0
ZNF684	1155.0
MSTN	1143.0
ZNF10	1137.0
RAD1	1126.0
NR1H3	1117.0
ZNF771	1093.0
GAD2	1092.0
MIR24-1	1070.0
NRBP1	1035.0
RXRG	1022.0
PPM1A	968.0
HSPD1	963.0
CNOT2	924.0
ZNF665	902.0
CPSF7	901.0
DLX5	876.0
ZNF692	868.0
ZNF799	861.0
PIP4K2C	856.0
MLST8	854.0
NOP2	837.0
AURKB	823.0
ING2	816.0
SMAD1	803.0
TPX2	786.0
CCNC	775.0
EED	774.0
ZNF70	764.0
ZNF256	762.0
SNAPC5	734.0
CBFB	714.0
IWS1	635.0
CBX6	622.0
TGFA	600.0
HDAC11	599.0
ZNF197	590.0
PCNA	570.0
ZKSCAN4	534.0
AKT3	516.0
FANCC	498.0
PPP2CB	497.0
OPRM1	481.0
ATRIP	448.0
ZNF548	392.0
CSF1R	383.0
ZNF124	381.0
PAPOLA	320.0
YAF2	315.0
ZNF479	307.0
CSTF1	299.0
ZNF606	291.0
ZNF793	251.0
TBL1XR1	245.0
DPY30	230.0
CDKN2A	229.0
MEN1	220.0
ZNF34	174.0
YWHAB	170.0
YEATS4	145.0
ZNF649	122.0
EIF4A3	121.0
CDK6	85.0
APOE	71.0
RORC	64.0
ZNF202	51.0
KCTD1	-4.0
E2F5	-8.0
NR5A1	-18.0
COX7C	-37.0
ZNF583	-145.0
NCBP1	-175.0
IQSEC3	-181.0
TAF9	-183.0
ZNF521	-188.0
HEY2	-193.0
ZNF221	-237.0
NEDD4L	-256.0
H4C9	-276.0
PRDM7	-278.0
CHTOP	-280.0
MNAT1	-336.0
TEAD3	-368.0
ZNF234	-383.0
TP53RK	-391.0
RRAGD	-414.0
ZNF558	-426.0
TFAP2E	-443.0
ZNF774	-450.0
ZNF195	-460.0
NAMPT	-469.0
FOXO6	-520.0
CTSV	-522.0
ZNF20	-528.0
ZNF215	-550.0
VDR	-578.0
H2AX	-614.0
ZNF732	-630.0
FOXO1	-655.0
L3MBTL1	-677.0
NBN	-689.0
MYL9	-693.0
ZNF514	-694.0
SP1	-714.0
TFAP2D	-723.0
ZNF709	-726.0
RAD51	-729.0
SSRP1	-796.0
ZNF17	-800.0
MAML3	-810.0
ZNF773	-837.0
ZNF568	-853.0
SKP2	-864.0
ASH2L	-865.0
EZH2	-873.0
ZNF540	-875.0
ZNF492	-879.0
MED31	-881.0
WWOX	-904.0
ZNF417	-988.0
TAF11	-999.0
ZFHX3	-1056.0
ZNF770	-1059.0
ZNF718	-1077.0
NPY	-1082.0
VEGFA	-1084.0
ZNF175	-1094.0
ZNF875	-1095.0
SCO1	-1148.0
ZNF614	-1156.0
FOS	-1163.0
CRADD	-1171.0
RRM2B	-1174.0
TRIM28	-1179.0
ZNF141	-1199.0
ANAPC2	-1206.0
ZNF585B	-1215.0
LSM10	-1225.0
ZNF287	-1228.0
ZNF625	-1239.0
CTR9	-1278.0
YBX1	-1287.0
TEAD2	-1293.0
ZNF266	-1294.0
PITX2	-1327.0
ZNF682	-1344.0
RAD50	-1348.0
ZIM3	-1354.0
CGA	-1355.0
LSM11	-1356.0
GTF2F2	-1392.0
SRSF7	-1396.0
ZNF610	-1399.0
CCN2	-1443.0
PRELID1	-1452.0
UBE2D1	-1471.0
PRDX2	-1476.0
MDC1	-1484.0
GAMT	-1491.0
CCND1	-1519.0
TNFRSF10C	-1520.0
MED20	-1528.0
PCGF5	-1539.0
HNF4A	-1547.0
ZNF442	-1550.0
NOTCH2	-1608.0
ZNF660	-1617.0
ZNF454	-1628.0
ITGA4	-1629.0
RUNX1	-1638.0
PPP1R13L	-1666.0
ZNF302	-1677.0
POLR2L	-1678.0
ZNF519	-1692.0
ZNF543	-1833.0
GAD1	-1857.0
EAF1	-1859.0
CDK9	-1861.0
RHNO1	-1864.0
POU4F2	-1871.0
ZNF730	-1877.0
ZNF727	-1885.0
RBBP5	-1889.0
MAML2	-1951.0
RGCC	-1968.0
BNIP3L	-2005.0
GRIN2B	-2027.0
ZNF577	-2042.0
RRAGC	-2062.0
TFAP2C	-2068.0
RARA	-2083.0
PPP2CA	-2084.0
NR6A1	-2089.0
MIR132	-2098.0
ZNF429	-2141.0
ZNF180	-2164.0
SNAPC2	-2172.0
ZNF418	-2214.0
FAS	-2215.0
RBX1	-2227.0
ZNF772	-2228.0
UBA52	-2237.0
ITGBL1	-2239.0
CAMK4	-2240.0
PERP	-2247.0
ZNF706	-2282.0
ZNF333	-2285.0
ZNF184	-2287.0
SETD9	-2288.0
NPM1	-2297.0
CDK2	-2309.0
UBB	-2335.0
POU2F1	-2358.0
ZNF263	-2368.0
RNF2	-2391.0
TP73	-2448.0
JUNB	-2450.0
SIRT3	-2452.0
ZNF25	-2490.0
ZFP28	-2494.0
PHAX	-2500.0
SPI1	-2508.0
NR2E1	-2530.0
LEO1	-2535.0
ZNF470	-2548.0
ZNF343	-2574.0
GRIA2	-2588.0
PPARGC1B	-2589.0
ZNF273	-2602.0
CDC7	-2614.0
ZNF586	-2640.0
SMAD4	-2666.0
TFAP2A	-2715.0
ZNF43	-2731.0
RORA	-2774.0
ZNF300	-2816.0
NABP2	-2829.0
CLDN5	-2837.0
NR3C1	-2846.0
NUAK1	-2855.0
H2BC26	-2895.0
RSPO3	-2899.0
ITGA2B	-2910.0
PSMB9	-2938.0
CCNE1	-2947.0
ZNF669	-2987.0
PVALB	-2994.0
SRSF2	-3015.0
SNAPC1	-3100.0
EXO1	-3131.0
ZNF776	-3143.0
ZNF140	-3160.0
KRAS	-3161.0
SLBP	-3174.0
MEF2C	-3189.0
SESN2	-3193.0
BARD1	-3201.0
CCNG1	-3203.0
DLL1	-3208.0
RET	-3209.0
BMP2	-3214.0
RBFOX3	-3220.0
ZNF471	-3251.0
NR5A2	-3280.0
WWTR1	-3291.0
CDKN2B	-3314.0
ZNF790	-3316.0
ZNF114	-3325.0
COX18	-3348.0
ZNF135	-3354.0
CCNE2	-3373.0
TEAD1	-3375.0
REST	-3392.0
FIP1L1	-3399.0
LAMTOR5	-3417.0
ZNF30	-3445.0
ZNF703	-3477.0
GRIN2A	-3522.0
SUMO1	-3539.0
SLC38A9	-3577.0
NR3C2	-3588.0
INTS14	-3593.0
KLF4	-3598.0
FKBP5	-3607.0
RAD17	-3609.0
ATF2	-3617.0
NLRC4	-3619.0
COL1A2	-3644.0
ZNF320	-3647.0
NFKB1	-3689.0
ZNF445	-3721.0
H2AZ2	-3800.0
ZNF792	-3825.0
MAPK11	-3828.0
UBE2C	-3845.0
POLR2K	-3852.0
ZFP1	-3884.0
COX20	-3906.0
CTSL	-3923.0
SMAD6	-3948.0
RNPS1	-3954.0
ZNF79	-3972.0
ZNF587	-4065.0
CCNA1	-4120.0
ZNF517	-4125.0
NR1H4	-4138.0
ESRRB	-4168.0
ZNF334	-4185.0
MAF	-4229.0
ZNF75A	-4237.0
SOD2	-4248.0
SNW1	-4266.0
PLXNA4	-4290.0
PLK2	-4300.0
PRMT6	-4318.0
CCNT2	-4325.0
PSMA5	-4331.0
CCND2	-4351.0
ZNF697	-4363.0
RBFOX1	-4365.0
SERPINB13	-4368.0
UCMA	-4390.0
TBX5	-4405.0
ZNF155	-4406.0
SESN3	-4443.0
BDNF	-4451.0
H2BC1	-4453.0
TRIAP1	-4479.0
BIRC5	-4539.0
RPRD1A	-4555.0
ZNF557	-4572.0
ZNF208	-4674.0
SCO2	-4677.0
NR4A2	-4692.0
GLI2	-4713.0
NOTCH4	-4715.0
TFAP2B	-4812.0
BBC3	-4813.0
CRH	-4840.0
NABP1	-4854.0
CAMK2D	-4902.0
STUB1	-4920.0
PRKAA2	-4922.0
H3C6	-4925.0
ZNF415	-4943.0
ZNF212	-4946.0
ZNF354C	-4956.0
ZNF440	-4990.0
NKX2-5	-5045.0
PSMD8	-5050.0
ZNF761	-5086.0
AGO4	-5113.0
ZNF595	-5125.0
ZNF621	-5157.0
CAMK2B	-5202.0
SERPINE1	-5210.0
SMARCE1	-5238.0
MIR137	-5328.0
ZFP37	-5386.0
TCF7L1	-5402.0
H2AC14	-5418.0
ACTL6B	-5469.0
TWIST2	-5507.0
G6PC1	-5508.0
ZNF285	-5519.0
ZNF354B	-5529.0
NR2F1	-5542.0
KIT	-5670.0
TAF10	-5681.0
PRKAG3	-5700.0
ESRRG	-5726.0
YAP1	-5728.0
H2BC3	-5733.0
PAX5	-5770.0
AUTS2	-5784.0
ARNT2	-5788.0
NKX3-2	-5869.0
H4C16	-5871.0
AFF4	-5889.0
MSX2	-5915.0
ZNF804B	-5922.0
CCNA2	-5945.0
HAND2	-5951.0
HUS1	-5999.0
THBS1	-6013.0
POLR2C	-6018.0
SMARCD3	-6048.0
ZNF214	-6083.0
MMP13	-6119.0
HNF4G	-6133.0
RORB	-6135.0
TP63	-6137.0
PCGF2	-6146.0
TJP1	-6230.0
BCL2L14	-6235.0
ZNF562	-6244.0
DLX6	-6297.0
LMO1	-6318.0
SUPT4H1	-6345.0
INS	-6353.0
OPRK1	-6371.0
TP53BP2	-6425.0
GATA4	-6509.0
PCGF6	-6538.0
ZIK1	-6552.0
ZNF480	-6599.0
TAL1	-6609.0
RARB	-6668.0
KCNIP3	-6685.0
H3C3	-6688.0
EGFR	-6730.0
TP53I3	-6772.0
PGR	-6783.0
ZNF99	-6791.0
MET	-6906.0
GLI3	-6913.0
SATB2	-6943.0
ELOA2	-7031.0
H2BC14	-7035.0
SYT10	-7110.0
NOTCH3	-7112.0
TNFRSF18	-7183.0
H4C12	-7199.0
LAMTOR2	-7256.0
SST	-7285.0
LIFR	-7310.0
CAMK2A	-7340.0
RABGGTB	-7411.0
HDAC2	-7451.0
SEM1	-7461.0
NFE2	-7492.0
HDAC9	-7549.0
MIR27A	-7560.0
ZNF552	-7592.0
THRB	-7619.0
PPARG	-7622.0
ZNF596	-7694.0
ZNF860	-7783.0
H3C12	-7844.0
CASP1	-7866.0
IHH	-7870.0
ZNF704	-7896.0
ZNF432	-7911.0
SOX2	-8005.0
ZNF677	-8050.0
ZKSCAN7	-8103.0
BAX	-8183.0
GCK	-8188.0
SOCS3	-8205.0
E2F1	-8231.0
BGLAP	-8235.0
COL1A1	-8277.0
OCLN	-8300.0
NPPA	-8306.0
NR4A1	-8308.0
VENTX	-8322.0
ZNF729	-8418.0
ZNF676	-8430.0
MIR24-2	-8446.0
ZNF675	-8479.0
CR1	-8489.0
GEM	-8494.0
IFNG	-8567.5
SFN	-8574.0
ZNF154	-8656.0
ZNF483	-8790.0
ZNF112	-8846.0
CSF2	-8958.0
SPP1	-8995.0
PCK1	-9092.0
TRIM63	-9231.0
IGFBP1	-9400.0

---

REACTOME_CELL_CYCLE

REACTOME_CELL_CYCLE

	190
set	REACTOME_CELL_CYCLE
setSize	666
pANOVA	5.82e-29
s.dist	0.253
p.adjustANOVA	3.19e-26

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PIAS4	11883
CSNK1D	11871
CEP250	11821
POLR2J	11816
REC8	11568
H2BC15	11524
SYCE2	11522
RANGAP1	11517
E2F6	11512
TFDP1	11506
RCC2	11484
H4C5	11447
INCENP	11431
DYNLL2	11413
POLR2A	11407
POLR2E	11395
PCNT	11389
DIDO1	11376
H2BC6	11322
ESPL1	11271

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PIAS4	11883.0
CSNK1D	11871.0
CEP250	11821.0
POLR2J	11816.0
REC8	11568.0
H2BC15	11524.0
SYCE2	11522.0
RANGAP1	11517.0
E2F6	11512.0
TFDP1	11506.0
RCC2	11484.0
H4C5	11447.0
INCENP	11431.0
DYNLL2	11413.0
POLR2A	11407.0
POLR2E	11395.0
PCNT	11389.0
DIDO1	11376.0
H2BC6	11322.0
ESPL1	11271.0
FZR1	11268.0
NUMA1	11246.0
TUBGCP3	11180.0
ORC1	11169.0
UBE2I	11138.0
PSMB4	11076.0
PPP6C	11008.0
PPP2R1B	10998.0
NCAPD2	10988.0
SMC1B	10987.0
DCTN3	10909.0
UBE2V2	10901.0
PSMD4	10893.0
RAE1	10890.0
SPAST	10889.0
PSMD13	10870.0
H2AZ1	10867.0
RAD9A	10850.0
CHMP4B	10836.0
FKBPL	10800.0
POLD4	10789.0
SUN2	10776.0
MCM7	10739.0
PPP2R5D	10733.0
AHCTF1	10728.0
DAXX	10716.0
PSMA2	10707.0
POLD1	10687.0
DYNC1H1	10679.0
YWHAE	10677.0
RPA1	10676.0
HAUS5	10645.0
CDC25B	10580.0
NSD2	10532.0
CDC23	10475.0
ANAPC15	10466.0
CTC1	10457.0
NUP210	10455.0
CENPN	10448.0
PSMC6	10418.0
PAFAH1B1	10395.0
PIF1	10391.0
TEN1	10350.0
POLR2B	10306.0
TINF2	10303.0
CEP152	10291.0
E2F4	10203.0
HJURP	10184.0
CDCA8	10170.0
NUP62	10167.0
DYNC1LI2	10120.0
SGO1	10062.0
RMI2	10057.0
NUP85	10023.0
CENPF	10012.0
PSMD3	9979.0
CDC25C	9899.0
FBXL18	9869.0
NUP54	9855.0
RMI1	9852.0
PSMD7	9804.0
AKT1	9802.0
TUBGCP2	9732.0
PSMC4	9692.0
NSL1	9660.0
ANAPC1	9651.0
SRC	9630.0
MCM2	9629.0
PSMD2	9598.0
YWHAG	9563.0
GOLGA2	9561.0
CENPS	9547.0
CENPJ	9539.0
CSNK1E	9526.0
NUP88	9522.0
H2AC4	9477.0
PSMB5	9461.0
TUBGCP6	9408.0
EP300	9390.0
BUB1B	9388.0
CDKN1B	9381.0
MZT2A	9358.0
POLD2	9355.0
NUP133	9347.0
NUDC	9330.0
BTRC	9324.0
CEP290	9276.0
CC2D1B	9258.0
CLASP1	9232.0
UIMC1	9223.0
PPME1	9189.0
KMT5A	9179.0
NCAPH2	9175.0
SIRT2	9115.0
HERC2	9108.0
H4C6	9077.0
RAB8A	9068.0
HAUS8	9058.0
PRKACA	9014.0
PSMF1	9002.0
CENPP	9001.0
POLE	8933.0
ZWILCH	8932.0
PHF20	8925.0
MAX	8923.0
H3C11	8908.0
CHMP2A	8906.0
H2BC10	8901.0
XPO1	8891.0
STAG1	8828.0
BANF1	8827.0
MASTL	8824.0
NDEL1	8779.0
TFDP2	8744.0
POLA2	8682.0
CNTRL	8628.0
BABAM1	8603.0
SET	8592.0
DSCC1	8582.0
PSMB7	8555.0
LIG1	8548.0
LEMD2	8502.0
NUP93	8494.0
MIS18A	8493.0
PSMA4	8487.0
CCNH	8458.0
CDC14A	8451.0
POLR2H	8450.0
DHFR	8442.0
SMC2	8434.0
RFC2	8432.0
AKT2	8422.0
CEP72	8407.0
RBL2	8353.0
CLIP1	8310.0
PPP1R12B	8283.0
H2AC6	8277.0
CHMP2B	8258.0
H4C11	8241.0
POM121	8233.0
SMC3	8217.0
CEP63	8212.0
BLZF1	8202.0
PMF1	8197.0
CDCA5	8184.0
NUP50	8160.0
AAAS	8159.0
NUP58	8140.0
CKAP5	8128.0
CDK11B	8120.0
H4C13	8117.0
TOPBP1	8095.0
ANAPC16	8064.0
MND1	8034.0
CHMP4A	8022.0
H4C1	8017.0
FBXW11	8014.0
PSMB1	7978.0
PSMA6	7971.0
CEP192	7966.0
DNA2	7894.0
TUBG2	7860.0
NUP98	7826.0
KNTC1	7772.0
BLM	7764.0
SFI1	7760.0
CSNK2A1	7758.0
H2AC8	7728.0
CDC45	7713.0
PSME2	7675.0
ANAPC4	7652.0
PSMD1	7564.0
ANAPC5	7558.0
H2BC4	7539.0
MAPK3	7526.0
RPS27A	7499.0
LBR	7494.0
PSME1	7470.0
COP1	7448.0
MCM8	7433.0
RBBP8	7402.0
H3C1	7395.0
FOXM1	7294.0
SHQ1	7265.0
SUN1	7260.0
H2BC9	7228.5
H3C7	7228.5
TEX12	7206.0
CDC27	7198.0
DCTN1	7179.0
CKS1B	7134.0
NEK6	7102.0
MSH5	7078.0
H4C8	7058.0
PSMA3	7039.0
MAD1L1	7020.0
PSMA1	6977.0
HAUS6	6964.0
PSMD6	6942.0
CDKN2D	6927.0
CDK11A	6900.0
DSN1	6888.0
KIF18A	6886.0
RSF1	6834.0
TERF2IP	6812.0
GORASP2	6781.0
CDC16	6748.0
PRKCB	6744.0
NUP37	6708.0
PSMB3	6665.0
H3C10	6652.0
PSMD11	6649.0
RNF8	6625.0
FEN1	6610.0
CDK5RAP2	6570.0
PPP2R2D	6543.0
MLH1	6506.0
TPR	6489.0
RPS27	6477.0
ZNF385A	6469.0
PDS5A	6446.0
PSMD12	6422.0
PRIM2	6418.0
PSMB6	6370.0
ACTR1A	6363.0
CEP57	6346.0
ANAPC10	6338.0
H2BC8	6334.0
NUP160	6322.0
NDE1	6318.0
GORASP1	6304.0
PSMD5	6295.0
PSME3	6289.0
MCM4	6281.0
CNEP1R1	6255.0
MAU2	6250.0
H2BC12	6220.0
PSMC3IP	6179.0
ABL1	6174.0
MDM4	6157.0
SMARCA5	6154.0
MYC	6135.0
CDK7	6114.0
PCM1	6109.0
PPP1R12A	6096.0
CENPM	6069.0
HDAC1	6062.0
JAK2	6056.0
TOP2A	6036.0
CENPL	6013.0
YWHAQ	5997.0
RBL1	5966.0
CSNK2A2	5953.0
PSMD9	5939.0
H3C4	5911.0
PRKCA	5835.0
MAPK1	5826.0
GSK3B	5797.0
ANAPC11	5794.0
VPS4A	5772.0
SYCP2	5771.0
ORC5	5764.0
SEH1L	5744.0
ANKLE2	5726.0
CENPE	5720.0
CDC26	5692.0
CENPC	5654.0
CENPU	5624.0
E2F3	5600.0
CSNK2B	5559.0
ORC6	5505.0
TOP3A	5504.0
HMMR	5486.0
CDC6	5426.0
RUVBL2	5400.0
PSMB2	5390.0
UBC	5385.0
NUP42	5371.0
ARPP19	5356.0
H4C3	5297.0
CENPK	5296.0
CEP164	5278.0
NIPBL	5277.0
AURKA	5237.0
POLR2I	5214.0
RPA2	5194.0
ORC3	5191.0
H2AJ	5141.0
DYNC1LI1	5132.0
CENPQ	5131.0
CCND3	5083.0
CHMP7	5074.0
MDM2	5073.0
RFC5	5072.0
CEP131	5065.0
RAN	5055.0
PSMA7	5054.0
PPP2R5C	5016.0
KAT5	5000.0
POLR2G	4982.0
CHEK1	4981.0
EML4	4980.0
CLASP2	4967.0
RANBP2	4890.0
SEC13	4854.0
RCC1	4850.0
DYRK1A	4839.0
NUP214	4833.0
PLK4	4782.0
LYN	4661.0
WAPL	4638.0
LCMT1	4631.0
POLR2F	4630.0
TERT	4580.0
PPP6R3	4532.0
NCAPD3	4509.0
RFC4	4504.0
B9D2	4467.0
TUBB	4460.0
PSMA8	4378.0
CHMP6	4359.0
PPP2R1A	4310.0
GTSE1	4307.0
KIF2A	4282.0
OIP5	4269.0
SGO2	4264.0
KIF2B	4249.0
TUBA4A	4239.0
RAB2A	4233.0
DYNLL1	4203.0
CEP43	4180.0
MCM5	4177.0
TUBB2A	4122.0
ODF2	4100.0
PSMC2	4047.0
WRN	4033.0
TK1	4031.0
CUL1	4015.0
RNF168	4001.0
H4C2	3987.0
PSMB10	3971.0
BUB3	3920.0
TUBB2B	3907.0
MCM3	3886.0
RBBP4	3878.0
YWHAH	3875.0
BUB1	3874.0
TERF1	3831.0
BRIP1	3816.0
TUBA4B	3811.0
CENPO	3792.0
ANAPC7	3782.0
NEDD1	3777.0
CHMP3	3762.0
AKAP9	3759.0
ZWINT	3720.0
TNPO1	3709.0
SKP1	3705.0
HSP90AB1	3700.0
LIN52	3662.0
TAOK1	3609.0
TUBGCP4	3597.0
H4C4	3596.0
MRE11	3571.0
WRAP53	3559.0
H3C8	3521.0
TP53	3499.0
NCAPG2	3483.0
PLK1	3472.0
UBE2E1	3470.0
LIN54	3409.0
H2AC20	3382.0
POLE3	3344.0
ORC4	3333.0
PSMC3	3323.0
CHTF18	3294.0
NUP107	3276.0
CTDNEP1	3265.0
LEMD3	3263.0
POLR2D	3258.0
KIF20A	3253.0
SDCCAG8	3232.0
PSMC1	3148.0
RPA3	3146.0
PSME4	3137.0
DCTN2	3135.0
GINS2	3128.0
HAUS4	3083.0
NDC1	3079.0
PSMC5	3065.0
LIN37	3058.0
H3-3B	3055.0
TP53BP1	3014.0
RAD51C	2979.0
GINS3	2975.0
H2AC18	2954.5
H2AC19	2954.5
TERF2	2921.0
MYBL2	2911.0
VRK2	2848.0
SPO11	2822.0
H2AC7	2792.5
H2BC7	2792.5
NEK2	2787.0
BRCA1	2780.0
MIS12	2770.0
RRM2	2760.0
IST1	2752.0
H2BC21	2718.0
RFC3	2692.0
NHP2	2655.0
TYMS	2640.0
NUP188	2493.0
ESCO2	2436.0
CDKN1A	2387.0
NUP35	2378.0
TUBB4B	2340.0
STAG3	2332.0
PPP1CC	2315.0
PSMB8	2300.0
GINS1	2279.0
AJUBA	2275.0
CDK4	2268.0
H3-3A	2262.0
TUBG1	2186.0
KNL1	2176.0
ATR	2151.0
RAD9B	2147.0
ATM	2137.0
CCNB1	2131.0
GMNN	2115.0
H2BC5	2100.0
PCBP4	2069.0
POM121C	2036.0
MCPH1	2033.0
CHEK2	1906.0
PSMD14	1903.0
PPP1CB	1887.0
UBE2S	1865.0
H2BC17	1857.0
H2BC13	1834.0
H3C2	1828.0
ENSA	1750.0
CLSPN	1743.0
RAB1A	1737.0
PSMB11	1723.0
MLH3	1625.0
STN1	1586.0
PPP2R5A	1572.0
SKA2	1570.0
GAR1	1431.0
CDK1	1360.0
RB1	1359.0
NDC80	1352.0
LMNB1	1327.0
PHLDA1	1309.0
H2BC11	1286.0
YWHAZ	1179.0
SYNE2	1162.0
RAD1	1126.0
CDC25A	1124.0
SYCE3	1105.0
KIF23	1051.0
TUBA1A	1018.0
NUF2	899.0
CABLES1	824.0
AURKB	823.0
TPX2	786.0
CCP110	730.0
POLE2	695.0
RAB1B	655.0
NEK9	629.0
CDC20	611.0
PDS5B	610.0
PCNA	570.0
NUP43	561.0
CDKN2C	549.0
AKT3	516.0
PPP2CB	497.0
NEK7	489.0
CHTF8	482.0
ATRIP	448.0
SMC4	404.0
NUP205	331.0
PRIM1	283.0
PPP2R5B	256.0
CDKN2A	229.0
LPIN1	218.0
YWHAB	170.0
TUBB6	150.0
USO1	135.0
CCNB2	97.0
CDK6	85.0
BRCA2	38.0
KPNB1	32.0
RFC1	4.0
E2F5	-8.0
PPP2R5E	-53.0
TMPO	-93.0
MAPRE1	-157.0
BABAM2	-162.0
H4C9	-276.0
MNAT1	-336.0
TUBB4A	-357.0
TUBA8	-372.0
LIN9	-393.0
H2AX	-614.0
NBN	-689.0
GINS4	-690.0
RAD51	-729.0
FBXO5	-747.0
WEE1	-761.0
SYCE1	-863.0
SKP2	-864.0
NME7	-869.0
KIF2C	-1021.0
CEP78	-1096.0
SSNA1	-1130.0
ANAPC2	-1206.0
CEP76	-1238.0
HSPA2	-1245.0
CENPA	-1250.0
RAD50	-1348.0
NOP10	-1391.0
UBE2D1	-1471.0
MDC1	-1484.0
CEP70	-1485.0
HAUS1	-1510.0
CCND1	-1519.0
POLD3	-1564.0
CDT1	-1582.0
PPP2R2A	-1648.0
RTEL1	-1651.0
POLR2L	-1678.0
FKBP6	-1693.0
POT1	-1694.0
RHNO1	-1864.0
PKMYT1	-1881.0
ITGB3BP	-1974.0
CENPT	-2031.0
LPIN2	-2041.0
PTTG1	-2060.0
PPP2CA	-2084.0
ACD	-2160.5
RBX1	-2227.0
UBA52	-2237.0
CEP41	-2263.0
ORC2	-2295.0
NPM1	-2297.0
CDK2	-2309.0
UBB	-2335.0
NCAPG	-2420.0
MCM10	-2444.0
MAD2L1	-2478.0
ZW10	-2497.0
MSH4	-2506.0
HAUS3	-2507.0
NUP153	-2541.0
ABRAXAS1	-2572.0
BORA	-2587.0
POLE4	-2612.0
CDC7	-2614.0
CENPH	-2615.0
DYNC1I2	-2797.0
TUBGCP5	-2825.0
H2BC26	-2895.0
PSMB9	-2938.0
CCNE1	-2947.0
E2F2	-3008.0
PTK6	-3078.0
ALMS1	-3091.0
CEP135	-3106.0
EXO1	-3131.0
BARD1	-3201.0
MCM6	-3207.0
NUP155	-3213.0
SYCP3	-3243.0
CDKN2B	-3314.0
RAD21	-3318.0
CCNE2	-3373.0
HSP90AA1	-3488.0
SYNE1	-3491.0
SUMO1	-3539.0
TUBA3D	-3545.0
TUBA1C	-3556.0
RAD17	-3609.0
SYCP1	-3700.0
H2AZ2	-3800.0
UBE2C	-3845.0
POLR2K	-3852.0
TUBB3	-4002.0
SPC25	-4088.0
CCNA1	-4120.0
RUVBL1	-4145.0
MIS18BP1	-4186.0
PSMA5	-4331.0
CCND2	-4351.0
TEX15	-4426.0
H2BC1	-4453.0
SKA1	-4482.0
BIRC5	-4539.0
TUBA3E	-4662.0
PRDM9	-4793.0
ESCO1	-4826.0
H3C6	-4925.0
VRK1	-4983.0
NCAPH	-5000.0
PSMD8	-5050.0
HAUS2	-5154.0
DYNC1I1	-5334.0
CENPW	-5376.0
H2AC14	-5418.0
LPIN3	-5512.0
SPDL1	-5533.0
H3-4	-5699.0
H2BC3	-5733.0
NINL	-5777.0
OPTN	-5780.0
H4C16	-5871.0
CCNA2	-5945.0
HUS1	-5999.0
POLR2C	-6018.0
DMC1	-6150.0
DBF4	-6276.0
TUBA1B	-6340.0
TUBB1	-6519.0
MZT1	-6533.0
H3C3	-6688.0
LMNA	-6774.0
CHMP4C	-6820.0
UBE2N	-6864.0
CDKN1C	-6865.0
H2BC14	-7035.0
H4C12	-7199.0
TUBA3C	-7269.0
TUBAL3	-7278.0
SEM1	-7461.0
SPC24	-7608.0
H3C12	-7844.0
FBXL7	-7868.0
ANKRD28	-7958.0
PRKAR2B	-7999.0
E2F1	-8231.0
SFN	-8574.0
MZT2B	-8863.0
TUBB8	-8942.0

---

REACTOME_CELL_CYCLE_MITOTIC

REACTOME_CELL_CYCLE_MITOTIC

	1112
set	REACTOME_CELL_CYCLE_MITOTIC
setSize	539
pANOVA	2.4e-25
s.dist	0.262
p.adjustANOVA	9.86e-23

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CSNK1D	11871
CEP250	11821
H2BC15	11524
RANGAP1	11517
E2F6	11512
TFDP1	11506
RCC2	11484
H4C5	11447
INCENP	11431
DYNLL2	11413
PCNT	11389
H2BC6	11322
ESPL1	11271
FZR1	11268
NUMA1	11246
TUBGCP3	11180
ORC1	11169
UBE2I	11138
PSMB4	11076
PPP2R1B	10998

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CSNK1D	11871.0
CEP250	11821.0
H2BC15	11524.0
RANGAP1	11517.0
E2F6	11512.0
TFDP1	11506.0
RCC2	11484.0
H4C5	11447.0
INCENP	11431.0
DYNLL2	11413.0
PCNT	11389.0
H2BC6	11322.0
ESPL1	11271.0
FZR1	11268.0
NUMA1	11246.0
TUBGCP3	11180.0
ORC1	11169.0
UBE2I	11138.0
PSMB4	11076.0
PPP2R1B	10998.0
NCAPD2	10988.0
DCTN3	10909.0
PSMD4	10893.0
RAE1	10890.0
SPAST	10889.0
PSMD13	10870.0
H2AZ1	10867.0
CHMP4B	10836.0
FKBPL	10800.0
POLD4	10789.0
MCM7	10739.0
PPP2R5D	10733.0
AHCTF1	10728.0
PSMA2	10707.0
POLD1	10687.0
DYNC1H1	10679.0
YWHAE	10677.0
RPA1	10676.0
HAUS5	10645.0
CDC25B	10580.0
CDC23	10475.0
ANAPC15	10466.0
NUP210	10455.0
CENPN	10448.0
PSMC6	10418.0
PAFAH1B1	10395.0
CEP152	10291.0
E2F4	10203.0
CDCA8	10170.0
NUP62	10167.0
DYNC1LI2	10120.0
SGO1	10062.0
NUP85	10023.0
CENPF	10012.0
PSMD3	9979.0
CDC25C	9899.0
FBXL18	9869.0
NUP54	9855.0
PSMD7	9804.0
AKT1	9802.0
TUBGCP2	9732.0
PSMC4	9692.0
NSL1	9660.0
ANAPC1	9651.0
SRC	9630.0
MCM2	9629.0
PSMD2	9598.0
YWHAG	9563.0
GOLGA2	9561.0
CENPS	9547.0
CENPJ	9539.0
CSNK1E	9526.0
NUP88	9522.0
H2AC4	9477.0
PSMB5	9461.0
TUBGCP6	9408.0
EP300	9390.0
BUB1B	9388.0
CDKN1B	9381.0
MZT2A	9358.0
POLD2	9355.0
NUP133	9347.0
NUDC	9330.0
BTRC	9324.0
CEP290	9276.0
CC2D1B	9258.0
CLASP1	9232.0
PPME1	9189.0
KMT5A	9179.0
NCAPH2	9175.0
SIRT2	9115.0
H4C6	9077.0
RAB8A	9068.0
HAUS8	9058.0
PRKACA	9014.0
PSMF1	9002.0
CENPP	9001.0
POLE	8933.0
ZWILCH	8932.0
MAX	8923.0
H3C11	8908.0
CHMP2A	8906.0
H2BC10	8901.0
XPO1	8891.0
STAG1	8828.0
BANF1	8827.0
MASTL	8824.0
NDEL1	8779.0
TFDP2	8744.0
POLA2	8682.0
CNTRL	8628.0
SET	8592.0
PSMB7	8555.0
LIG1	8548.0
LEMD2	8502.0
NUP93	8494.0
PSMA4	8487.0
CCNH	8458.0
CDC14A	8451.0
DHFR	8442.0
SMC2	8434.0
RFC2	8432.0
AKT2	8422.0
CEP72	8407.0
RBL2	8353.0
CLIP1	8310.0
PPP1R12B	8283.0
H2AC6	8277.0
CHMP2B	8258.0
H4C11	8241.0
POM121	8233.0
SMC3	8217.0
CEP63	8212.0
BLZF1	8202.0
PMF1	8197.0
CDCA5	8184.0
NUP50	8160.0
AAAS	8159.0
NUP58	8140.0
CKAP5	8128.0
CDK11B	8120.0
H4C13	8117.0
ANAPC16	8064.0
CHMP4A	8022.0
H4C1	8017.0
FBXW11	8014.0
PSMB1	7978.0
PSMA6	7971.0
CEP192	7966.0
DNA2	7894.0
TUBG2	7860.0
NUP98	7826.0
KNTC1	7772.0
SFI1	7760.0
CSNK2A1	7758.0
H2AC8	7728.0
CDC45	7713.0
PSME2	7675.0
ANAPC4	7652.0
PSMD1	7564.0
ANAPC5	7558.0
H2BC4	7539.0
MAPK3	7526.0
RPS27A	7499.0
LBR	7494.0
PSME1	7470.0
MCM8	7433.0
H3C1	7395.0
FOXM1	7294.0
H2BC9	7228.5
H3C7	7228.5
CDC27	7198.0
DCTN1	7179.0
CKS1B	7134.0
NEK6	7102.0
H4C8	7058.0
PSMA3	7039.0
MAD1L1	7020.0
PSMA1	6977.0
HAUS6	6964.0
PSMD6	6942.0
CDKN2D	6927.0
CDK11A	6900.0
DSN1	6888.0
KIF18A	6886.0
GORASP2	6781.0
CDC16	6748.0
PRKCB	6744.0
NUP37	6708.0
PSMB3	6665.0
H3C10	6652.0
PSMD11	6649.0
FEN1	6610.0
CDK5RAP2	6570.0
PPP2R2D	6543.0
TPR	6489.0
RPS27	6477.0
PDS5A	6446.0
PSMD12	6422.0
PRIM2	6418.0
PSMB6	6370.0
ACTR1A	6363.0
CEP57	6346.0
ANAPC10	6338.0
H2BC8	6334.0
NUP160	6322.0
NDE1	6318.0
GORASP1	6304.0
PSMD5	6295.0
PSME3	6289.0
MCM4	6281.0
CNEP1R1	6255.0
MAU2	6250.0
H2BC12	6220.0
ABL1	6174.0
MYC	6135.0
CDK7	6114.0
PCM1	6109.0
PPP1R12A	6096.0
CENPM	6069.0
HDAC1	6062.0
JAK2	6056.0
TOP2A	6036.0
CENPL	6013.0
RBL1	5966.0
CSNK2A2	5953.0
PSMD9	5939.0
H3C4	5911.0
PRKCA	5835.0
MAPK1	5826.0
GSK3B	5797.0
ANAPC11	5794.0
VPS4A	5772.0
ORC5	5764.0
SEH1L	5744.0
ANKLE2	5726.0
CENPE	5720.0
CDC26	5692.0
CENPC	5654.0
CENPU	5624.0
E2F3	5600.0
CSNK2B	5559.0
ORC6	5505.0
HMMR	5486.0
CDC6	5426.0
PSMB2	5390.0
UBC	5385.0
NUP42	5371.0
ARPP19	5356.0
H4C3	5297.0
CENPK	5296.0
CEP164	5278.0
NIPBL	5277.0
AURKA	5237.0
RPA2	5194.0
ORC3	5191.0
H2AJ	5141.0
DYNC1LI1	5132.0
CENPQ	5131.0
CCND3	5083.0
CHMP7	5074.0
RFC5	5072.0
CEP131	5065.0
RAN	5055.0
PSMA7	5054.0
PPP2R5C	5016.0
EML4	4980.0
CLASP2	4967.0
RANBP2	4890.0
SEC13	4854.0
RCC1	4850.0
DYRK1A	4839.0
NUP214	4833.0
PLK4	4782.0
LYN	4661.0
WAPL	4638.0
LCMT1	4631.0
NCAPD3	4509.0
RFC4	4504.0
B9D2	4467.0
TUBB	4460.0
PSMA8	4378.0
CHMP6	4359.0
PPP2R1A	4310.0
GTSE1	4307.0
KIF2A	4282.0
SGO2	4264.0
KIF2B	4249.0
TUBA4A	4239.0
RAB2A	4233.0
DYNLL1	4203.0
CEP43	4180.0
MCM5	4177.0
TUBB2A	4122.0
ODF2	4100.0
PSMC2	4047.0
TK1	4031.0
CUL1	4015.0
H4C2	3987.0
PSMB10	3971.0
BUB3	3920.0
TUBB2B	3907.0
MCM3	3886.0
RBBP4	3878.0
BUB1	3874.0
TUBA4B	3811.0
CENPO	3792.0
ANAPC7	3782.0
NEDD1	3777.0
CHMP3	3762.0
AKAP9	3759.0
ZWINT	3720.0
TNPO1	3709.0
SKP1	3705.0
HSP90AB1	3700.0
LIN52	3662.0
TAOK1	3609.0
TUBGCP4	3597.0
H4C4	3596.0
H3C8	3521.0
TP53	3499.0
NCAPG2	3483.0
PLK1	3472.0
UBE2E1	3470.0
LIN54	3409.0
H2AC20	3382.0
POLE3	3344.0
ORC4	3333.0
PSMC3	3323.0
NUP107	3276.0
CTDNEP1	3265.0
LEMD3	3263.0
KIF20A	3253.0
SDCCAG8	3232.0
PSMC1	3148.0
RPA3	3146.0
PSME4	3137.0
DCTN2	3135.0
GINS2	3128.0
HAUS4	3083.0
NDC1	3079.0
PSMC5	3065.0
LIN37	3058.0
H3-3B	3055.0
GINS3	2975.0
H2AC18	2954.5
H2AC19	2954.5
MYBL2	2911.0
VRK2	2848.0
H2AC7	2792.5
H2BC7	2792.5
NEK2	2787.0
MIS12	2770.0
RRM2	2760.0
IST1	2752.0
H2BC21	2718.0
RFC3	2692.0
TYMS	2640.0
NUP188	2493.0
ESCO2	2436.0
CDKN1A	2387.0
NUP35	2378.0
TUBB4B	2340.0
PPP1CC	2315.0
PSMB8	2300.0
GINS1	2279.0
AJUBA	2275.0
CDK4	2268.0
H3-3A	2262.0
TUBG1	2186.0
KNL1	2176.0
CCNB1	2131.0
GMNN	2115.0
H2BC5	2100.0
POM121C	2036.0
MCPH1	2033.0
PSMD14	1903.0
PPP1CB	1887.0
UBE2S	1865.0
H2BC17	1857.0
H2BC13	1834.0
H3C2	1828.0
ENSA	1750.0
RAB1A	1737.0
PSMB11	1723.0
PPP2R5A	1572.0
SKA2	1570.0
CDK1	1360.0
RB1	1359.0
NDC80	1352.0
LMNB1	1327.0
PHLDA1	1309.0
H2BC11	1286.0
CDC25A	1124.0
KIF23	1051.0
TUBA1A	1018.0
NUF2	899.0
CABLES1	824.0
AURKB	823.0
TPX2	786.0
CCP110	730.0
POLE2	695.0
RAB1B	655.0
NEK9	629.0
CDC20	611.0
PDS5B	610.0
PCNA	570.0
NUP43	561.0
CDKN2C	549.0
AKT3	516.0
PPP2CB	497.0
NEK7	489.0
SMC4	404.0
NUP205	331.0
PRIM1	283.0
PPP2R5B	256.0
CDKN2A	229.0
LPIN1	218.0
TUBB6	150.0
USO1	135.0
CCNB2	97.0
CDK6	85.0
KPNB1	32.0
RFC1	4.0
E2F5	-8.0
PPP2R5E	-53.0
TMPO	-93.0
MAPRE1	-157.0
H4C9	-276.0
MNAT1	-336.0
TUBB4A	-357.0
TUBA8	-372.0
LIN9	-393.0
H2AX	-614.0
GINS4	-690.0
FBXO5	-747.0
WEE1	-761.0
SKP2	-864.0
NME7	-869.0
KIF2C	-1021.0
CEP78	-1096.0
SSNA1	-1130.0
ANAPC2	-1206.0
CEP76	-1238.0
CENPA	-1250.0
UBE2D1	-1471.0
CEP70	-1485.0
HAUS1	-1510.0
CCND1	-1519.0
POLD3	-1564.0
CDT1	-1582.0
PPP2R2A	-1648.0
PKMYT1	-1881.0
ITGB3BP	-1974.0
CENPT	-2031.0
LPIN2	-2041.0
PTTG1	-2060.0
PPP2CA	-2084.0
RBX1	-2227.0
UBA52	-2237.0
CEP41	-2263.0
ORC2	-2295.0
CDK2	-2309.0
UBB	-2335.0
NCAPG	-2420.0
MCM10	-2444.0
MAD2L1	-2478.0
ZW10	-2497.0
HAUS3	-2507.0
NUP153	-2541.0
BORA	-2587.0
POLE4	-2612.0
CDC7	-2614.0
CENPH	-2615.0
DYNC1I2	-2797.0
TUBGCP5	-2825.0
H2BC26	-2895.0
PSMB9	-2938.0
CCNE1	-2947.0
E2F2	-3008.0
PTK6	-3078.0
ALMS1	-3091.0
CEP135	-3106.0
MCM6	-3207.0
NUP155	-3213.0
CDKN2B	-3314.0
RAD21	-3318.0
CCNE2	-3373.0
HSP90AA1	-3488.0
SUMO1	-3539.0
TUBA3D	-3545.0
TUBA1C	-3556.0
H2AZ2	-3800.0
UBE2C	-3845.0
TUBB3	-4002.0
SPC25	-4088.0
CCNA1	-4120.0
PSMA5	-4331.0
CCND2	-4351.0
H2BC1	-4453.0
SKA1	-4482.0
BIRC5	-4539.0
TUBA3E	-4662.0
ESCO1	-4826.0
H3C6	-4925.0
VRK1	-4983.0
NCAPH	-5000.0
PSMD8	-5050.0
HAUS2	-5154.0
DYNC1I1	-5334.0
H2AC14	-5418.0
LPIN3	-5512.0
SPDL1	-5533.0
H3-4	-5699.0
H2BC3	-5733.0
NINL	-5777.0
OPTN	-5780.0
H4C16	-5871.0
CCNA2	-5945.0
DBF4	-6276.0
TUBA1B	-6340.0
TUBB1	-6519.0
MZT1	-6533.0
H3C3	-6688.0
LMNA	-6774.0
CHMP4C	-6820.0
CDKN1C	-6865.0
H2BC14	-7035.0
H4C12	-7199.0
TUBA3C	-7269.0
TUBAL3	-7278.0
SEM1	-7461.0
SPC24	-7608.0
H3C12	-7844.0
FBXL7	-7868.0
PRKAR2B	-7999.0
E2F1	-8231.0
MZT2B	-8863.0
TUBB8	-8942.0

---

REACTOME_KERATINIZATION

REACTOME_KERATINIZATION

	1073
set	REACTOME_KERATINIZATION
setSize	210
pANOVA	8.5e-24
s.dist	-0.402
p.adjustANOVA	2.79e-21

Top enriched genes

Top 20 genes

GeneID	Gene Rank
KRT16	-9729
KRTAP19-8	-9691
LCE2B	-9688
KRTAP4-6	-9648
LCE3A	-9586
KRTAP12-2	-9582
KRT74	-9563
KRTAP11-1	-9558
KRTAP1-4	-9522
KRTAP3-3	-9486
KRTAP1-3	-9461
KRT78	-9433
LCE6A	-9410
KRTAP19-4	-9383
KRTAP15-1	-9355
KRTAP23-1	-9349
KRT17	-9314
SPRR1A	-9303
KRT9	-9259
KRT71	-9222

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
KRT16	-9729
KRTAP19-8	-9691
LCE2B	-9688
KRTAP4-6	-9648
LCE3A	-9586
KRTAP12-2	-9582
KRT74	-9563
KRTAP11-1	-9558
KRTAP1-4	-9522
KRTAP3-3	-9486
KRTAP1-3	-9461
KRT78	-9433
LCE6A	-9410
KRTAP19-4	-9383
KRTAP15-1	-9355
KRTAP23-1	-9349
KRT17	-9314
SPRR1A	-9303
KRT9	-9259
KRT71	-9222
KRT14	-9168
LIPN	-9162
KRTAP17-1	-9140
SPINK9	-9125
CSTA	-9117
KRT79	-9057
KRTAP9-3	-9047
KRTAP19-1	-8994
KRT24	-8984
PI3	-8964
KRTAP6-2	-8952
LCE1F	-8934
KRT32	-8922
KRTAP4-5	-8888
SPRR2A	-8886
KRT76	-8877
KRT19	-8875
KRTAP19-3	-8831
KRTAP9-9	-8814
KRTAP9-6	-8794
KRT7	-8765
KRT27	-8669
KLK12	-8668
CASP14	-8663
RPTN	-8620
DSG2	-8585
SPRR3	-8576
KRT18	-8526
KRTAP6-3	-8469
KRTAP2-3	-8424
KRT72	-8420
KRT23	-8416
SPRR2E	-8387
KRT37	-8329
LCE1B	-8307
KRTAP24-1	-8288
KRTAP20-1	-8236
FLG	-8228
KRTAP22-1	-8220
LCE3E	-8172
DSC2	-8062
KRTAP5-11	-8052
LCE4A	-8035
KRTAP5-1	-8028
KRTAP13-4	-7873
KRTAP5-5	-7871
KLK13	-7818
LCE1C	-7815
KRTAP2-2	-7778
KRTAP21-1	-7612
KRTAP13-1	-7571
KRTAP3-2	-7561
KRT38	-7396
KRTAP6-1	-7352
DSG1	-7296
KRT3	-7286
KRTAP4-2	-7159
SPRR1B	-6979
KRT4	-6978
KRT75	-6835
KRTAP4-7	-6826
KRTAP19-6	-6822
KRTAP1-5	-6808
KLK8	-6694
KRT81	-6666
DSG4	-6639
LCE3B	-6614
KRT31	-6546
KRT86	-6474
KRT15	-6470
KRTAP9-1	-6384
KRT20	-6319
KRTAP26-1	-6182
SPINK5	-6071
KRTAP16-1	-6031
KRTAP2-1	-5912
KRTAP12-1	-5858
KRTAP27-1	-5683
KRTAP21-3	-5466
KRTAP2-4	-5442
KRTAP4-11	-5419
CELA2A	-5368
KRT84	-5331
KRTAP10-8	-5214
KLK14	-5129
PKP3	-5051
LCE2D	-4950
LCE2A	-4834
KRTAP9-4	-4779
KRTAP20-2	-4750
KRT2	-4726
SPRR2D	-4680
CDSN	-4652
KRTAP1-1	-4636
JUP	-4358
IVL	-4353
KRTAP21-2	-4283
KRT40	-4045
SPINK6	-4009
KAZN	-3890
KLK5	-3849
KRT83	-3794
KRT33B	-3726
KRTAP10-7	-3635
KRTAP10-10	-3523
SPRR2G	-3470
KRT82	-3334
EVPL	-3257
KRTAP5-4	-3094
DSC3	-2978
KRT10	-2870
KRT12	-2785
KRTAP12-3	-2769
PKP1	-2665
KRTAP3-1	-2658
KRTAP9-2	-2341
PERP	-2247
KRTAP29-1	-2208
KRT28	-2144
KRTAP13-3	-2136
PCSK6	-2082
KRT8	-1922
KRT36	-1903
KRTAP10-12	-1868
KRTAP5-9	-1812
KRT85	-1758
KRTAP25-1	-1655
KRT34	-1110
KRTAP19-5	-868
KRTAP19-2	-793
LIPJ	-734
KRT25	-394
KRT26	-62
KRTAP19-7	-17
PRSS8	102
KRTAP4-8	194
KRT13	312
SPRR2F	341
KRTAP10-6	507
PPL	727
PKP2	884
KRTAP5-6	948
CAPNS1	967
LIPK	1477
KRT33A	2225
LCE3D	2278
DSG3	2280
KRTAP5-2	2293
DSP	2356
CAPN1	2455
KRT80	2463
KRTAP8-1	2602
PKP4	2931
KRTAP10-3	3157
KRT6C	3159
KRT35	3721
KRT73	4034
KRT5	4037
ST14	4464
KRT77	4576
KRT6B	5705
KRTAP5-3	5718
TCHH	6333
KRTAP4-1	6571
KRT6A	6595
KRTAP12-4	6877
DSC1	6986
KRTAP10-5	7298
KRTAP10-1	7341
LCE5A	7379
LCE1A	7487
KRTAP5-10	7654
KRT39	8886
FURIN	8913
LCE1E	9234
KRTAP10-11	9290
LELP1	9420
KRT1	9530
KRTAP10-4	10334
KRTAP13-2	10715
KRTAP5-8	10748
KRTAP10-9	10809
KRTAP4-3	11085
TGM5	11292
KRTAP4-4	11365
LIPM	11525
TGM1	11686
KRTAP10-2	11922
KRTAP5-7	11959
LCE2C	12081

---

REACTOME_INFECTIOUS_DISEASE

REACTOME_INFECTIOUS_DISEASE

	974
set	REACTOME_INFECTIOUS_DISEASE
setSize	910
pANOVA	1.24e-20
s.dist	0.182
p.adjustANOVA	3.32e-18

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IFNA21	12243
BRD4	12047
CD79B	12044
MAP2K2	12024
IFNA13	11954
TAB1	11909
LCK	11904
FCGR3A	11842
PDPK1	11829
POLR2J	11816
SUPT5H	11758
CREBBP	11715
CD28	11682
MGAT5	11655
MYH9	11645
AP2M1	11598
GANAB	11567
H2BC15	11524
PRKACG	11518
RANGAP1	11517

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IFNA21	12243.0
BRD4	12047.0
CD79B	12044.0
MAP2K2	12024.0
IFNA13	11954.0
TAB1	11909.0
LCK	11904.0
FCGR3A	11842.0
PDPK1	11829.0
POLR2J	11816.0
SUPT5H	11758.0
CREBBP	11715.0
CD28	11682.0
MGAT5	11655.0
MYH9	11645.0
AP2M1	11598.0
GANAB	11567.0
H2BC15	11524.0
PRKACG	11518.0
RANGAP1	11517.0
H4C5	11447.0
DYNLL2	11413.0
POLR2A	11407.0
TYK2	11396.0
POLR2E	11395.0
ADCY7	11370.0
RPL32	11326.0
H2BC6	11322.0
AP2A2	11289.0
SEC24B	11267.0
JAK1	11216.0
DVL1	11215.0
MTA1	11188.0
ST3GAL1	11158.0
TGFB1	11148.0
UBE2I	11138.0
PSMB4	11076.0
PPIH	11075.0
GATAD2A	11072.0
CBL	11060.0
NCOR2	11049.0
IRF7	11031.0
DPEP2	11005.0
ST6GALNAC4	10981.0
PSMD4	10893.0
RAE1	10890.0
CHD3	10888.0
GEMIN2	10880.0
PSMD13	10870.0
ERCC3	10866.0
GNGT2	10852.0
CHMP4B	10836.0
IKBKB	10825.0
EEF2	10808.0
SAP30L	10745.0
GNB1	10735.0
DAXX	10716.0
PSMA2	10707.0
GTF2A1	10680.0
DYNC1H1	10679.0
YWHAE	10677.0
AP1B1	10665.0
H2AC15	10614.0
PARP1	10610.0
SH3GL1	10596.0
RPL26	10573.0
MYO9B	10547.0
ELOB	10535.0
GNB3	10486.0
NUP210	10455.0
RPN1	10453.0
PSMC6	10418.0
CTNND1	10415.0
CRK	10343.0
POLR2B	10306.0
TLR9	10244.0
PAK2	10228.0
NCOR1	10213.0
IFNA5	10179.0
NUP62	10167.0
TAF4	10162.0
DUSP16	10143.0
RNF135	10134.0
DYNC1LI2	10120.0
NELFCD	10110.0
ST6GAL1	10106.0
RPS9	10077.0
VPS39	10049.0
CHD4	10037.0
NUP85	10023.0
ATP1A2	10009.0
CYFIP2	10003.0
PSMD3	9979.0
SNRPD2	9957.0
DVL3	9939.0
STAT2	9911.0
RIPK1	9907.0
SOS1	9884.0
NUP54	9855.0
GEMIN7	9853.0
TAF13	9847.0
H2AC12	9830.0
PSMD7	9804.0
AKT1	9802.0
CHMP1A	9800.0
RPL6	9786.0
CD247	9759.0
RIPK2	9756.0
NELFB	9731.0
MYO1C	9714.0
PSMC4	9692.0
ENTPD5	9689.0
AP1M2	9672.0
ANO10	9648.0
ZDHHC3	9645.0
SRC	9630.0
RPL27A	9619.0
PSMD2	9598.0
YWHAG	9563.0
MGAT1	9560.0
S1PR1	9555.0
CPSF4	9551.0
NUP88	9522.0
PPIA	9515.0
SNRPB	9514.0
PTGES3	9495.0
H2AC4	9477.0
IMPDH1	9469.0
PSMB5	9461.0
RAC1	9456.0
SIKE1	9430.0
RPN2	9419.0
ST3GAL2	9407.0
GOLGA7	9404.0
RPL19	9400.0
EP300	9390.0
ADORA2B	9373.0
NUP133	9347.0
NCKAP1L	9332.0
BTRC	9324.0
ARPC3	9321.0
RPL34	9275.0
RAB7A	9267.0
SEC24C	9238.0
ZDHHC2	9217.0
RPL14	9168.0
PTPN6	9161.0
STT3A	9152.0
ST6GALNAC2	9138.0
RPL41	9118.0
CALM1	9105.0
GNG11	9097.0
H4C6	9077.0
VPS37C	9072.0
VPS37B	9063.0
ELMO2	9037.0
ITPR3	9019.0
PRKACA	9014.0
IL1A	9007.0
BCL2L1	9006.0
PSMF1	9002.0
NCKIPSD	8987.0
MGAT4A	8966.0
GRB2	8934.0
FURIN	8913.0
H3C11	8908.0
CHMP2A	8906.0
H2BC10	8901.0
XPO1	8891.0
UVRAG	8871.0
BANF1	8827.0
TCEA1	8796.0
GNAI2	8783.0
NELFE	8758.0
APOBEC3G	8739.0
H2AC11	8737.0
RPLP1	8728.0
CREB1	8716.0
VPS16	8712.0
ARPC2	8695.0
MAVS	8672.0
MAP2K6	8671.0
CCNT1	8657.0
NELFA	8636.0
GTF2F1	8571.0
GNG10	8565.0
HGS	8560.0
MAN2A1	8557.0
PSMB7	8555.0
LIG1	8548.0
TKFC	8542.0
SRPK1	8535.0
RCOR1	8525.0
NUP93	8494.0
PSMA4	8487.0
ARPC4	8481.0
CCNK	8473.0
CCNH	8458.0
POLR2H	8450.0
VPS4B	8449.0
IFNA14	8436.0
PRKCSH	8430.0
VPS33A	8424.0
AKT2	8422.0
VPS11	8421.0
GEMIN5	8367.0
ABI1	8363.0
ISCU	8347.0
YES1	8329.0
DDX20	8304.0
ANO8	8288.0
H2AC6	8277.0
CHMP2B	8258.0
ZBP1	8243.0
H4C11	8241.0
PARP10	8240.0
PML	8234.0
POM121	8233.0
GNGT1	8221.0
RPS15	8218.0
SV2A	8215.0
NUP50	8160.0
AAAS	8159.0
NUP58	8140.0
H4C13	8117.0
KDM1A	8061.0
RPL22	8037.0
CHMP4A	8022.0
H4C1	8017.0
PSMB1	7978.0
PSMA6	7971.0
GSK3A	7969.0
VPS28	7949.0
IFNGR2	7930.0
TAF3	7849.0
NUP98	7826.0
WIPF2	7821.0
AP2S1	7803.0
IRF3	7763.0
MVB12B	7759.0
CHUK	7753.0
CSNK1A1	7752.0
H2AC8	7728.0
CYBA	7724.0
RNF213	7718.0
TAF2	7715.0
CLTC	7714.0
PSME2	7675.0
TSG101	7622.0
MBD3	7608.0
ARID4A	7579.0
PSMD1	7564.0
H2BC4	7539.0
MAPK3	7526.0
RPS27A	7499.0
PSME1	7470.0
HMOX1	7469.0
TXNIP	7462.0
TAF4B	7454.0
GTF2E1	7447.0
H3C1	7395.0
PABPN1	7394.0
MTA3	7374.0
ELL	7361.0
SAP30	7289.0
RPS23	7245.0
H2BC9	7228.5
H3C7	7228.5
RPS10	7219.0
SUGT1	7203.0
NCBP2	7200.0
TRIM4	7175.0
P2RX4	7089.0
IFNA6	7062.0
H4C8	7058.0
RIPK3	7046.0
RAB5A	7043.0
HNRNPK	7040.0
PSMA3	7039.0
SNF8	7007.0
PSMA1	6977.0
PSMD6	6942.0
H2AC17	6904.0
KPNA2	6903.0
ATP1B3	6875.0
CRBN	6852.0
PARP14	6800.0
GNG5	6795.0
ATP1B2	6791.0
RPS20	6789.0
GPS2	6767.0
IL18	6728.0
NUP37	6708.0
SAP18	6685.0
H2AC21	6681.0
SUDS3	6677.0
PSMB3	6665.0
H3C10	6652.0
PSMD11	6649.0
FEN1	6610.0
CDC42	6603.0
WASF2	6601.0
MAP2K7	6577.0
VPS18	6553.0
SUPT16H	6552.0
RNGTT	6547.0
IPO5	6542.0
TPR	6489.0
RPS27	6477.0
PSMD12	6422.0
TAF1L	6402.0
PSMB6	6370.0
H2BC8	6334.0
STAM2	6329.0
NUP160	6322.0
PSMD5	6295.0
PSME3	6289.0
CNBP	6259.0
C3AR1	6258.0
XRCC5	6243.0
VPS45	6241.0
PCBP2	6238.0
SFPQ	6237.0
H2BC12	6220.0
RPS2	6180.0
ABL1	6174.0
STAT1	6170.0
GNG7	6169.0
IL6	6166.0
RPS15A	6160.0
ZDHHC5	6151.0
ARPC1B	6122.0
CDK7	6114.0
CYFIP1	6113.0
GNG2	6075.0
HDAC1	6062.0
JAK2	6056.0
ACTB	6053.0
RELA	6020.0
RPS16	6017.0
PLCG1	6015.0
G3BP2	6006.0
YWHAQ	5997.0
RPL15	5994.0
PSMD9	5939.0
H3C4	5911.0
MAN1B1	5909.0
GNB2	5886.0
RPL11	5878.0
SLC25A4	5865.0
PRKAR2A	5856.0
IFNGR1	5853.0
VPS37D	5847.0
MAPK1	5826.0
AP1M1	5820.0
GSK3B	5797.0
VPS4A	5772.0
PACS1	5766.0
SEH1L	5744.0
AP2A1	5736.0
ATG14	5723.0
SFTPD	5668.0
FNTB	5666.0
ST3GAL4	5650.0
DNAJC3	5642.0
JUN	5629.0
FXYD2	5619.0
GNG3	5611.0
TBP	5601.0
SUZ12	5592.0
ANO9	5591.0
GTF2H3	5566.0
H2AC16	5532.0
MGAT4B	5506.0
CD3G	5500.0
PDCD1	5491.0
ELOA	5436.0
GNB4	5421.0
HDAC3	5406.0
GNB5	5393.0
PSMB2	5390.0
UBC	5385.0
RPL35A	5375.0
NUP42	5371.0
NFKB2	5335.0
H4C3	5297.0
VPS37A	5285.0
GNAT3	5265.0
SRPK2	5235.0
HBEGF	5232.0
G3BP1	5217.0
POLR2I	5214.0
FXYD3	5181.0
MAPK14	5180.0
CORO1A	5173.0
ERCC2	5135.0
DYNC1LI1	5132.0
SNAP25	5125.0
PTPN11	5117.0
CHMP7	5074.0
RAN	5055.0
PSMA7	5054.0
ITCH	5050.0
POLR2G	4982.0
PARP4	4966.0
COMT	4955.0
GNAS	4912.0
RANBP2	4890.0
RCAN3	4888.0
FCGR2A	4869.0
SEC13	4854.0
RCC1	4850.0
GTF2H1	4840.0
NUP214	4833.0
PDCD6IP	4812.0
SAR1B	4809.0
VPS36	4766.0
ST3GAL3	4765.0
TAF7	4746.0
LYN	4661.0
DOCK2	4642.0
POLR2F	4630.0
TRIM27	4525.0
PRKAR1A	4512.0
RPL29	4480.0
XRCC4	4468.0
UBAP1	4463.0
TUBB	4460.0
RPS14	4403.0
JAK3	4397.0
PSMA8	4378.0
CHMP6	4359.0
ADCY4	4346.0
AP2B1	4341.0
RPL28	4311.0
CANX	4306.0
TUBA4A	4239.0
DYNLL1	4203.0
GEMIN4	4198.0
TAB2	4143.0
TUBB2A	4122.0
SNRPF	4099.0
ITPR1	4088.0
H2AC13	4085.0
VPS33B	4055.0
PSMC2	4047.0
ELMO1	4026.0
TAF15	4012.0
H4C2	3987.0
PSMB10	3971.0
GATAD2B	3962.0
CUL5	3961.0
RPL31	3951.0
DDOST	3936.0
RPS3A	3917.0
SNRPE	3915.0
TUBB2B	3907.0
RBBP4	3878.0
YWHAH	3875.0
WASL	3866.0
TUBA4B	3811.0
WASF1	3787.0
IFNA2	3780.0
HNRNPA1	3775.0
SEC24D	3773.0
CHMP3	3762.0
ADCY3	3756.0
GTF2H5	3727.0
SKP1	3705.0
CBLL1	3701.0
HSP90AB1	3700.0
CD8B	3697.0
ZDHHC20	3687.0
CXCR4	3682.0
VPS41	3678.0
ANO7	3626.0
SNRPD3	3606.0
SMN1	3599.5
SMN2	3599.5
H4C4	3596.0
IL17RA	3536.0
H3C8	3521.0
RPL35	3510.0
PIK3C3	3509.0
IL1R1	3466.0
MTA2	3431.0
RNMT	3418.0
SMAD3	3402.0
H2AC20	3382.0
PRMT1	3343.0
PSMC3	3323.0
ITGB1	3314.0
NUP107	3276.0
AP1S3	3259.0
POLR2D	3258.0
PRKAR1B	3218.0
KPNA4	3209.0
RPL18	3205.0
RPL9	3178.0
RPS29	3176.0
RPS24	3174.0
PSMC1	3148.0
PSME4	3137.0
NDC1	3079.0
PSMC5	3065.0
ATP6V1H	3050.0
SEC24A	3029.0
DAD1	3027.0
H2AC18	2954.5
H2AC19	2954.5
PPIG	2920.0
EDEM2	2890.0
CUL3	2861.0
ELOC	2833.0
ANO6	2826.0
GTF2B	2820.0
H2AC7	2792.5
H2BC7	2792.5
BAIAP2	2775.0
HSPA1A	2773.0
H2BC21	2718.0
WIPF1	2711.0
GTF2E2	2708.0
CAV1	2698.0
TRAF3	2674.0
ROCK2	2635.0
MAP3K7	2632.0
MOGS	2631.0
RPL21	2628.0
ARID4B	2538.0
NUP188	2493.0
RPS3	2461.0
NMT1	2410.0
VTA1	2396.0
NUP35	2378.0
P2RX7	2370.0
RPL4	2357.0
TUBB4B	2340.0
RPS27L	2306.0
PSMB8	2300.0
GALNT1	2285.0
CTNNB1	2250.0
RPL10A	2208.0
CTDP1	2201.0
RPL12	2178.0
ARPC5	2177.0
SNRPD1	2163.0
AGRN	2109.0
H2BC5	2100.0
GTF2H4	2092.0
ADCY9	2080.0
TXN	2053.0
TXNRD1	2049.0
POM121C	2036.0
NCK1	2028.0
PARP8	2020.0
TOMM70	2006.0
TAF6	1945.0
NMI	1918.0
PSMD14	1903.0
SNRPG	1899.0
VAMP1	1893.0
H2BC17	1857.0
HSPG2	1852.0
TAF12	1849.0
H2BC13	1834.0
H3C2	1828.0
ARF1	1827.0
EIF2AK2	1775.0
RPL13A	1771.5
DDX5	1755.0
TAF5	1730.0
RHBDF2	1729.0
PSMB11	1723.0
KEAP1	1708.0
ACTR2	1697.0
ARPC1A	1646.0
CALR	1632.0
MAP1LC3B	1577.0
FAU	1541.0
DVL2	1535.0
FUT8	1510.0
PLCG2	1474.0
RPL36	1472.0
SV2C	1435.0
CYSLTR2	1423.0
CLTA	1420.0
RB1	1359.0
GTF2A2	1343.0
H2AC25	1333.0
RPS21	1329.0
PKLR	1319.0
H2BC11	1286.0
SYK	1248.0
MYO5A	1219.0
YWHAZ	1179.0
RPL37	1116.0
TUBA1A	1018.0
PARP16	999.0
RPS18	992.0
IFNA1	952.0
VCP	920.0
AP1S1	908.0
RPL30	897.0
GNAI3	892.0
NFE2L2	886.0
HLA-C	871.0
BLNK	865.0
XRCC6	839.0
LIG4	829.0
HCK	797.0
EED	774.0
GSDMD	771.0
STAM	744.0
ITPR2	728.0
NLRP3	615.0
NUP43	561.0
RPS6	524.0
AKT3	516.0
LARP1	493.0
TLR1	477.0
AHCYL1	464.0
RPS7	463.0
NOD1	457.0
MVB12A	451.0
NCKAP1	438.0
PATJ	412.0
NUP205	331.0
TBL1XR1	245.0
BECN1	214.0
TRAF6	213.0
APP	210.0
ANTXR2	184.0
YWHAB	170.0
SIGMAR1	152.0
TUBB6	150.0
IL17F	118.0
FYN	61.0
IMPDH2	37.0
KPNB1	32.0
STX1A	31.0
TUFM	-79.0
GNAI1	-91.0
ROCK1	-121.0
PARP9	-139.0
CD9	-154.0
GGT1	-163.0
NCBP1	-175.0
ENTPD1	-178.0
TAF9	-183.0
RPL18A	-240.0
NEDD4L	-256.0
RPL23	-261.0
RPL27	-270.0
H4C9	-276.0
MNAT1	-336.0
TUBB4A	-357.0
TUBA8	-372.0
VAV3	-395.0
KPNA3	-397.0
RPLP0	-487.0
CD79A	-494.0
GNG4	-501.0
BRMS1	-568.0
IFNAR1	-615.0
VHL	-675.0
SDC1	-687.0
FGR	-692.0
SP1	-714.0
MAP2K1	-762.0
GNAZ	-788.0
SSRP1	-796.0
PARP6	-797.0
NMT2	-806.0
SEC23A	-814.0
EZH2	-873.0
NRP1	-909.0
KPNA1	-925.0
SDC4	-927.0
TAF11	-999.0
ABI2	-1037.0
AP1G1	-1050.0
VEGFA	-1084.0
ZCRB1	-1100.0
ADCY6	-1112.0
ATP1A4	-1159.0
PTK2	-1164.0
TRIM28	-1179.0
IL1B	-1211.0
MAP2K4	-1231.0
GRSF1	-1256.0
FKBP1A	-1286.0
GTF2F2	-1392.0
VAV1	-1402.0
EEF1A1	-1425.0
MAPK8	-1441.0
ZDHHC11	-1543.0
RPS13	-1554.0
TRIM25	-1558.0
TBK1	-1590.0
PYCARD	-1614.0
MASP2	-1627.0
ITGA4	-1629.0
RUNX1	-1638.0
HMG20B	-1643.0
PRKACB	-1645.0
POLR2L	-1678.0
MAP2K3	-1689.0
STX1B	-1705.0
FKBP4	-1761.0
MYH2	-1794.0
GPC2	-1810.0
CDK9	-1861.0
RANBP1	-1938.0
PSIP1	-1996.0
FNTA	-2037.0
RPL26L1	-2195.0
RPSA	-2216.0
ACTR3	-2226.0
RBX1	-2227.0
CDH1	-2234.0
UBA52	-2237.0
RPL7	-2286.0
IFIH1	-2291.0
NPM1	-2297.0
NOXO1	-2306.0
NT5E	-2312.0
NFKBIA	-2315.0
UBB	-2335.0
RPS5	-2392.0
SYT2	-2401.0
ATP1A1	-2451.0
PALS1	-2462.0
GNG13	-2505.0
NUP153	-2541.0
ACTG1	-2553.0
RPS28	-2610.0
MGAT2	-2643.5
RPL36AL	-2643.5
CBX1	-2648.0
SMAD4	-2666.0
CHMP5	-2668.0
UBE2V1	-2729.0
WNT5A	-2742.0
DPEP3	-2743.0
DOCK1	-2756.0
DYNC1I2	-2797.0
VAV2	-2813.0
GNG12	-2840.0
NR3C1	-2846.0
H2BC26	-2895.0
RPS12	-2916.0
RIGI	-2937.0
PSMB9	-2938.0
PIK3R4	-2946.0
ZDHHC8	-2964.0
NOS2	-3058.0
GEMIN6	-3184.0
NUP155	-3213.0
RPL22L1	-3311.0
REST	-3392.0
PHF21A	-3413.0
SV2B	-3473.0
HSP90AA1	-3488.0
RPL39L	-3504.0
SUMO1	-3539.0
TUBA3D	-3545.0
TUBA1C	-3556.0
SDC2	-3558.0
ENO1	-3565.0
FXYD7	-3664.0
RPL5	-3668.0
NFKB1	-3689.0
EPS15	-3782.0
GPC1	-3783.0
NOD2	-3808.0
ANO4	-3816.0
POLR2K	-3852.0
CTSL	-3923.0
TUBB3	-4002.0
IFNAR2	-4013.0
CD4	-4035.0
FZD7	-4037.0
RPS11	-4060.0
PSTPIP1	-4107.0
IRAK2	-4121.0
RPL3L	-4134.0
RPS19	-4241.0
H2AC1	-4272.0
PLK2	-4300.0
CCNT2	-4325.0
PSMA5	-4331.0
RPL17	-4430.0
ATP1A3	-4442.0
TLR2	-4444.0
HLA-G	-4445.0
H2BC1	-4453.0
NLRP12	-4478.0
RPL3	-4491.0
SYT1	-4532.0
ISG15	-4552.0
RPLP2	-4579.0
ATP1B1	-4593.0
TUBA3E	-4662.0
RPL7A	-4734.0
HLA-A	-4744.0
MBL2	-4749.0
MYO10	-4783.0
ADAM17	-4787.0
H3C6	-4925.0
ANO2	-4953.0
RPL23A	-4959.0
ANO1	-4994.0
NOXA1	-4995.0
C3	-5027.0
PSMD8	-5050.0
IL6R	-5053.0
IL17RC	-5170.0
SERPINE1	-5210.0
KPNA5	-5222.0
IFNB1	-5278.0
RPL10L	-5285.0
CEBPD	-5317.0
DYNC1I1	-5334.0
MEFV	-5350.0
H2AC14	-5418.0
ANO5	-5501.0
RPL24	-5518.0
TAF10	-5681.0
H2BC3	-5733.0
H4C16	-5871.0
BRK1	-5954.0
ST6GALNAC3	-5968.0
SH3GL2	-5994.0
POLR2C	-6018.0
HLA-E	-6091.0
VPS25	-6097.0
WASF3	-6206.0
ADCY2	-6209.0
TJP1	-6230.0
FXYD6	-6257.0
RPL38	-6279.0
PPIB	-6305.0
RPL13	-6322.0
TUBA1B	-6340.0
SUPT4H1	-6345.0
RPL8	-6372.0
DPEP1	-6431.0
RPS8	-6455.0
TUSC3	-6483.0
ANTXR1	-6498.0
TUBB1	-6519.0
RPS25	-6687.0
H3C3	-6688.0
EGFR	-6730.0
HAVCR1	-6743.0
ADCY1	-6750.0
CHMP4C	-6820.0
UBE2N	-6864.0
VAMP2	-6867.0
MET	-6906.0
ADCY8	-6973.0
ELOA2	-7031.0
H2BC14	-7035.0
RPL37A	-7080.0
GJA1	-7142.0
IFNA16	-7167.0
B2M	-7174.0
H4C12	-7199.0
TUBA3C	-7269.0
TUBAL3	-7278.0
ADCY5	-7301.0
ANO3	-7429.0
HDAC2	-7451.0
SEM1	-7461.0
CRB3	-7511.0
HMGA1	-7614.0
FXYD4	-7795.0
H3C12	-7844.0
CASP1	-7866.0
BST2	-7869.0
MGAT4C	-7910.0
SH3GL3	-7913.0
FXYD1	-7917.0
CD163	-7947.0
TMPRSS2	-7949.0
PRKAR2B	-7999.0
GNG8	-8059.0
GPC6	-8086.0
MASP1	-8110.0
GGT5	-8154.0
LTF	-8382.0
GPC5	-8402.0
SFN	-8574.0
SDC3	-8606.0
RPS26	-8718.0
HLA-F	-8905.0
TUBB8	-8942.0
IL10	-8957.0
IKBKE	-8971.0
WIPF3	-9061.0
CCR5	-9073.0
STING1	-9081.0
KPNA7	-9158.0
GUCY2C	-9176.0
IL17A	-9413.0
HLA-B	-9476.0
IFNA8	-9593.0
CTSG	-9623.0
IFNA7	-9735.0

---

REACTOME_SENSORY_PERCEPTION

REACTOME_SENSORY_PERCEPTION

	1581
set	REACTOME_SENSORY_PERCEPTION
setSize	555
pANOVA	1.41e-20
s.dist	-0.231
p.adjustANOVA	3.32e-18

Top enriched genes

Top 20 genes

GeneID	Gene Rank
OR56B4	-9736
OR8H3	-9724
OR4C12	-9723
OR1L1	-9702
OR52E6	-9696
OR8A1	-9673
OR6Q1	-9604
OR8B4	-9573
OR51A7	-9562
OR8G5	-9527
CLPS	-9508
OR52E2	-9507
OR5A2	-9498
OR51T1	-9479
OR52I1	-9471
OR51M1	-9470
APOA4	-9459
OR10K2	-9445
OR5H6	-9442
TAS2R46	-9441

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
OR56B4	-9736.0
OR8H3	-9724.0
OR4C12	-9723.0
OR1L1	-9702.0
OR52E6	-9696.0
OR8A1	-9673.0
OR6Q1	-9604.0
OR8B4	-9573.0
OR51A7	-9562.0
OR8G5	-9527.0
CLPS	-9508.0
OR52E2	-9507.0
OR5A2	-9498.0
OR51T1	-9479.0
OR52I1	-9471.0
OR51M1	-9470.0
APOA4	-9459.0
OR10K2	-9445.0
OR5H6	-9442.0
TAS2R46	-9441.0
OR1S2	-9439.0
OR52R1	-9409.0
OR5I1	-9373.0
OR51F1	-9365.0
OR5B17	-9363.0
OR5B21	-9348.0
OR51B6	-9326.0
OR52A1	-9301.0
OR2W3	-9286.0
TAS2R16	-9282.0
LRRC52	-9256.0
OR13C4	-9239.0
OR56A1	-9221.0
OR6C4	-9210.0
OR9Q2	-9206.0
OR10W1	-9199.0
OR6V1	-9189.0
OTOGL	-9123.0
OR2S2	-9083.0
OR12D3	-9040.0
OR10G2	-9028.0
OR56B1	-9003.0
OR5M9	-8969.0
OR1A1	-8966.0
OR52N1	-8963.0
OR51L1	-8956.0
OR2H2	-8933.0
OR10S1	-8932.0
OR4D9	-8928.0
TTR	-8919.0
OR2F1	-8912.0
OR51G1	-8910.0
OR2B6	-8861.0
OR51D1	-8860.0
OR5B2	-8801.0
GUCA1B	-8780.0
HSD17B6	-8751.0
OR8B12	-8729.0
OR4A16	-8680.0
OR5T1	-8664.0
OR10V1	-8644.0
OR13C9	-8633.0
OTOP1	-8616.0
SDC3	-8606.0
OR4M1	-8599.0
OR2T12	-8552.0
OR5T3	-8535.0
OR56A4	-8510.0
OR6X1	-8504.0
TAS2R40	-8456.0
AKR1B10	-8439.0
OR6C74	-8423.0
OR10G4	-8412.0
OR2G2	-8403.0
GPC5	-8402.0
OR8S1	-8366.0
OR10J5	-8365.0
OR8U3	-8337.0
OR52A5	-8299.0
OR51F2	-8280.0
OR11A1	-8271.0
APOB	-8243.0
OR13F1	-8242.0
RHO	-8208.0
OR52B2	-8165.0
OR2AG1	-8148.0
OR6K2	-8132.0
OR8G1	-8101.0
TRPM5	-8088.0
GPC6	-8086.0
SCN4B	-8078.0
RBP4	-8063.0
XIRP2	-8024.0
OR4D11	-7998.0
GRXCR1	-7996.0
SLC17A8	-7959.0
OR9I1	-7876.0
OR4X2	-7875.0
OR5D14	-7847.0
OR1E2	-7846.0
OR2A12	-7817.0
OR5AK2	-7753.0
OR1E1	-7736.0
OR4K1	-7734.0
AKR1C1	-7730.0
OR2V2	-7699.0
OR6Y1	-7666.0
OR5B12	-7665.0
OR1A2	-7658.0
EPS8L2	-7649.0
OR6C3	-7638.0
TMIE	-7605.0
RDH12	-7562.0
OR14C36	-7537.0
OR10AG1	-7528.0
OR51I2	-7516.0
OR2L3	-7505.0
OR2AK2	-7455.0
GUCY2D	-7446.0
STRC	-7371.0
GRM4	-7350.0
OR52D1	-7336.0
OR4A5	-7302.0
PNLIP	-7275.0
OR9Q1	-7232.0
RBP2	-7207.0
KCNMA1	-7191.0
OR51E2	-7086.0
OR8J1	-7030.0
OR5W2	-7017.0
OR2M4	-7011.0
OR2L8	-6970.0
OR5V1	-6960.0
GRM1	-6953.0
OR6B3	-6934.0
OR4K14	-6925.0
OR51Q1	-6890.0
VAMP2	-6867.0
APOC2	-6852.0
TAS2R38	-6813.0
OR1B1	-6810.0
OR8D4	-6763.0
KCNN2	-6754.0
OR8K5	-6747.0
OR5L1	-6742.0
OR6B1	-6729.0
ATP2B2	-6684.0
GRK1	-6600.0
OR2F2	-6511.0
OR5M10	-6469.0
USH1C	-6416.0
OR6B2	-6370.0
OR4F15	-6368.0
SCN3A	-6331.0
OR9G4	-6299.0
OR11H6	-6298.0
OTOG	-6290.0
OR52N2	-6218.0
OR52H1	-6217.0
OR10G7	-6210.0
RBP3	-6190.0
OR4D2	-6181.0
TMC2	-6140.0
SCN2A	-6109.0
OR8K3	-6108.0
OR10J1	-6099.0
OR4A47	-6082.0
EPS8	-6053.0
REEP1	-6012.0
OR52I2	-6002.0
OR5AU1	-6001.0
ESPNL	-5974.0
STRA6	-5909.0
ESPN	-5822.0
OR51V1	-5752.0
RBP1	-5737.0
OR51B5	-5717.0
OR5D16	-5706.0
OR52E8	-5666.0
LRAT	-5646.0
OR2H1	-5590.0
OR2M2	-5497.0
OR8H1	-5453.0
OR5M1	-5443.0
OR2A2	-5426.0
OR6A2	-5417.0
OR6M1	-5267.0
TRPM4	-5227.0
BCO2	-5225.0
OR5P3	-5207.0
TAS2R50	-5193.0
PCLO	-5150.0
EPB41L3	-5088.0
OTOF	-4967.0
ANO2	-4953.0
OR13J1	-4901.0
MYO3A	-4882.0
RCVRN	-4855.0
RDH16	-4732.0
OR10A3	-4700.0
KCNJ2	-4696.0
CLIC5	-4665.0
OR10A5	-4643.0
PDE6B	-4637.0
PDE6A	-4524.0
OR7G3	-4497.0
OR9A2	-4473.0
OR6C70	-4449.0
EBF1	-4384.0
MYO3B	-4379.0
OR1M1	-4357.0
ABCA4	-4355.0
DHRS9	-4350.0
SCNN1D	-4309.0
OR2L13	-4284.0
SCN9A	-4238.0
OR1Q1	-4149.0
OR10H5	-4142.0
OR2AG2	-4080.0
CACNB2	-4078.0
RDH10	-4019.0
OR10T2	-4011.0
OR9G1	-3975.5
OR9G9	-3975.5
OR14J1	-3970.0
CYP4V2	-3947.0
EPB41L1	-3943.0
BSN	-3900.0
RLBP1	-3886.0
OR5L2	-3847.0
OR10A4	-3841.0
OR5AP2	-3837.0
SDR9C7	-3807.0
TAS2R1	-3790.0
GPC1	-3783.0
OR4K17	-3733.0
TPRN	-3722.0
APOC3	-3671.0
OR2Z1	-3625.0
OR4C15	-3621.0
RPE65	-3560.0
SDC2	-3558.0
OR7C1	-3529.0
CACNA2D2	-3503.0
CACNA1D	-3472.0
OR5B3	-3459.0
OR1L3	-3426.0
OR5C1	-3381.0
OR2T8	-3367.0
OR1N1	-3317.0
OR10A6	-3312.0
OR6C68	-3299.0
OR13G1	-3283.0
TAS2R31	-3272.0
OR4K13	-3241.0
OR51G2	-3223.0
OR5M3	-3215.0
GRK7	-3211.0
OR2B2	-3109.0
OR1L4	-3081.0
OR10A7	-3076.0
TAS1R1	-3055.0
USH1G	-3021.0
OR14A16	-3017.0
OR6C2	-3003.0
OR2A5	-2883.0
AKR1C4	-2878.0
OR10H1	-2810.0
OR11G2	-2738.0
OR2D2	-2736.0
OR52E4	-2734.0
CNGB1	-2670.0
OR52K2	-2659.0
OR2M3	-2650.0
ACTG1	-2553.0
PLCB2	-2536.0
SLC24A1	-2522.0
GNG13	-2505.0
OR4B1	-2492.0
OR13C2	-2438.0
OR12D2	-2418.0
OR4E2	-2413.0
OR10G8	-2376.0
SCN2B	-2336.0
LHX2	-2314.0
RAB3A	-2300.0
SLC26A5	-2149.0
OR5AC2	-2095.0
OR2G3	-2073.0
FNTA	-2037.0
OR7A10	-2020.0
OR10X1	-1961.0
RGS9	-1887.0
OR52M1	-1821.0
GPC2	-1810.0
OR4C46	-1808.0
LDLR	-1775.0
CABP2	-1743.0
OR2T33	-1698.0
GNAT1	-1688.0
OR14I1	-1683.0
KCNQ4	-1658.0
OR52K1	-1634.0
OR4L1	-1592.0
OR1F1	-1559.0
OR4A15	-1501.0
OR1C1	-1477.0
TMC1	-1448.0
OR10H2	-1397.0
LRP12	-1358.0
PLS1	-1338.0
OR7G1	-1317.0
OR5H1	-1150.0
WHRN	-1133.0
OR5AN1	-1129.0
RGS9BP	-1128.0
PCDH15	-1052.0
TAS1R2	-1046.0
TAS2R14	-1000.0
OR1S1	-963.0
OR10A2	-951.0
OR51B4	-948.0
SDC4	-927.0
MYO7A	-915.0
OR2M5	-912.0
CAMKMT	-888.0
NMT2	-806.0
OR1J2	-763.0
SDC1	-687.0
OR5F1	-686.0
OR2T4	-536.0
CDH23	-476.0
APOA1	-340.0
OR51I1	-304.0
EZR	-267.0
TWF1	-235.0
OR5P2	-233.0
CALHM3	-217.0
NAPEPLD	-213.0
OR5D18	-100.0
OR2AT4	-72.0
OR5A1	20.0
OR2W1	21.0
STX1A	31.0
APOE	71.0
OR5K4	162.0
OR2B3	177.0
OR51B2	232.0
OR51S1	253.0
OR56A3	277.0
OR8K1	335.0
GRXCR2	338.0
PDE6G	342.0
OR6S1	355.0
GSN	397.0
METAP1	399.0
CALHM1	501.0
OR2T3	514.0
LPL	569.0
OR5AS1	619.0
OR8U8	627.0
OR13A1	641.0
GNAL	654.0
CAPZA2	668.0
GUCA1C	703.0
OR5H2	896.0
OR6T1	1026.0
OR6K6	1146.0
OR52L1	1149.0
TAS2R20	1152.0
OR6K3	1160.0
RTP1	1178.0
LRP2	1207.0
OR2B11	1212.0
OR51A2	1236.0
OR4N2	1241.0
OR5K1	1379.0
PLB1	1447.0
OR56A5	1553.0
MYO15A	1569.0
FSCN2	1758.0
GUCA1A	1799.0
DHRS3	1838.0
HSPG2	1852.0
GRK4	1990.0
TAS2R8	2018.0
OR8J3	2079.0
OR3A1	2087.0
AGRN	2109.0
OR7G2	2140.0
OR4D10	2166.0
TAS2R7	2237.0
OR2G6	2295.0
OR5K2	2395.0
NMT1	2410.0
LRP1	2471.0
TAS2R41	2475.0
OR2T6	2511.0
OR2L2	2571.0
OR51E1	2601.0
OR1G1	2634.0
RDH8	2679.0
OR5J2	2727.0
CABP1	2757.0
OR4C45	2813.0
METAP2	2849.0
RTP2	2865.0
OR6C1	3033.0
OR52W1	3070.0
CAPZA1	3088.0
OR1L6	3092.0
TAS2R5	3112.0
OR2C1	3225.0
OR5T2	3242.0
SPTAN1	3255.0
SCN1B	3362.0
OR10C1	3427.0
OR4D6	3430.0
OR10H3	3446.0
OR8D2	3450.0
OR6C75	3490.0
RDX	3667.0
OR4K2	3738.0
ADCY3	3756.0
SCNN1B	3882.0
TAS2R4	3896.0
TAS2R39	3973.0
KCNMB1	4000.0
PRKCQ	4181.0
OR2C3	4192.0
OR5AR1	4229.0
LRP8	4318.0
OR10G9	4336.0
OR4C3	4356.0
OR5H15	4361.0
OR10P1	4394.0
OR9K2	4446.0
CNGA1	4484.0
OR8U1	4489.0
OR2T1	4612.0
SCNN1A	4693.0
OR6P1	4761.0
TRIOBP	4792.0
CNGA4	4992.0
LRP10	5007.0
CHRNA9	5091.0
SCNN1G	5092.0
SNAP25	5125.0
OR10K1	5185.0
OR4K15	5202.0
GNAT3	5265.0
OR6C76	5358.0
GNB5	5393.0
OR13D1	5594.0
OR8B8	5627.0
FNTB	5666.0
OR5M11	5706.0
TWF2	5714.0
OR4F6	5788.0
BCO1	5822.0
PRKCA	5835.0
AKR1C3	5902.0
ACTB	6053.0
LDB1	6071.0
OR7D4	6181.0
SPTBN1	6494.0
LHFPL5	6522.0
OR13C3	6620.0
OR2V1	6754.0
OR2T27	6829.0
ATP2B1	6840.0
OR4D5	7018.0
OR1I1	7124.0
OR9A4	7205.0
OR6C65	7257.0
RIPOR2	7287.0
OR10Q1	7303.0
OR6C6	7324.0
OR7C2	7372.0
OR2L5	7588.0
CTBP2	7617.0
TAS2R10	7676.0
OR1D2	7792.0
OR2AP1	7828.0
OR7A17	7851.0
HSD17B1	7924.0
CIB2	7941.0
CAPZB	7951.0
GPIHBP1	7989.0
OR8B2	8130.0
GNGT1	8221.0
OR4N5	8274.0
OR10AD1	8294.0
OR7D2	8295.0
OR4C16	8593.0
OR1L8	8661.0
APOM	8772.0
OR4D1	8776.0
PJVK	8791.0
OR1K1	8830.0
OR2M7	8998.0
ITPR3	9019.0
OR4S1	9096.0
CALM1	9105.0
OR10Z1	9194.0
OR4K5	9233.0
OR11H4	9335.0
OR6F1	9532.0
OPN1SW	9578.0
MYO1C	9714.0
OR52J3	9822.0
RDH11	9836.0
OR2J2	10163.0
RETSAT	10191.0
OR5M8	10201.0
OR2K2	10210.0
OR2A14	10276.0
OR10G3	10297.0
OR4C6	10320.0
OR10H4	10439.0
GNB3	10486.0
OR2T11	10578.0
OR13C8	10658.0
GNB1	10735.0
OR5K3	10777.0
OR3A2	11023.0
TAS2R3	11078.0
OR2Y1	11147.0
OR1J4	11187.0
DNAJC5	11192.0
OR1J1	11209.0
OR6N2	11236.0
OR7A5	11258.0
APOA2	11286.0
OR10J3	11316.0
TAS2R43	11381.0
OR4X1	11412.0
SAG	11480.0
OR8D1	11570.0
OR2AE1	11606.0
TAS1R3	11617.0
MYH9	11645.0
OR5D13	11705.0
TAS2R30	11710.0
OR11L1	11728.0
OR1N2	11734.0
OR6N1	11737.0
OR2D3	11846.0
TAS2R13	11892.0
OR52B6	11933.0
RDH5	11937.0
CHRNA10	11956.0
OR8I2	12022.0
OR3A3	12056.0
OR7E24	12147.0

---

REACTOME_M_PHASE

REACTOME_M_PHASE

	1096
set	REACTOME_M_PHASE
setSize	398
pANOVA	3.57e-20
s.dist	0.268
p.adjustANOVA	7.32e-18

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CSNK1D	11871
CEP250	11821
H2BC15	11524
RANGAP1	11517
RCC2	11484
H4C5	11447
INCENP	11431
DYNLL2	11413
PCNT	11389
H2BC6	11322
ESPL1	11271
NUMA1	11246
TUBGCP3	11180
UBE2I	11138
PSMB4	11076
PPP2R1B	10998
NCAPD2	10988
DCTN3	10909
PSMD4	10893
RAE1	10890

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CSNK1D	11871.0
CEP250	11821.0
H2BC15	11524.0
RANGAP1	11517.0
RCC2	11484.0
H4C5	11447.0
INCENP	11431.0
DYNLL2	11413.0
PCNT	11389.0
H2BC6	11322.0
ESPL1	11271.0
NUMA1	11246.0
TUBGCP3	11180.0
UBE2I	11138.0
PSMB4	11076.0
PPP2R1B	10998.0
NCAPD2	10988.0
DCTN3	10909.0
PSMD4	10893.0
RAE1	10890.0
SPAST	10889.0
PSMD13	10870.0
H2AZ1	10867.0
CHMP4B	10836.0
PPP2R5D	10733.0
AHCTF1	10728.0
PSMA2	10707.0
DYNC1H1	10679.0
YWHAE	10677.0
HAUS5	10645.0
CDC23	10475.0
ANAPC15	10466.0
NUP210	10455.0
CENPN	10448.0
PSMC6	10418.0
PAFAH1B1	10395.0
CEP152	10291.0
CDCA8	10170.0
NUP62	10167.0
DYNC1LI2	10120.0
SGO1	10062.0
NUP85	10023.0
CENPF	10012.0
PSMD3	9979.0
NUP54	9855.0
PSMD7	9804.0
TUBGCP2	9732.0
PSMC4	9692.0
NSL1	9660.0
ANAPC1	9651.0
PSMD2	9598.0
YWHAG	9563.0
GOLGA2	9561.0
CENPS	9547.0
CENPJ	9539.0
CSNK1E	9526.0
NUP88	9522.0
H2AC4	9477.0
PSMB5	9461.0
TUBGCP6	9408.0
BUB1B	9388.0
MZT2A	9358.0
NUP133	9347.0
NUDC	9330.0
CEP290	9276.0
CC2D1B	9258.0
CLASP1	9232.0
KMT5A	9179.0
NCAPH2	9175.0
SIRT2	9115.0
H4C6	9077.0
HAUS8	9058.0
PRKACA	9014.0
PSMF1	9002.0
CENPP	9001.0
ZWILCH	8932.0
H3C11	8908.0
CHMP2A	8906.0
H2BC10	8901.0
XPO1	8891.0
STAG1	8828.0
BANF1	8827.0
MASTL	8824.0
NDEL1	8779.0
CNTRL	8628.0
SET	8592.0
PSMB7	8555.0
LEMD2	8502.0
NUP93	8494.0
PSMA4	8487.0
SMC2	8434.0
CEP72	8407.0
CLIP1	8310.0
H2AC6	8277.0
CHMP2B	8258.0
H4C11	8241.0
POM121	8233.0
SMC3	8217.0
CEP63	8212.0
BLZF1	8202.0
PMF1	8197.0
CDCA5	8184.0
NUP50	8160.0
AAAS	8159.0
NUP58	8140.0
CKAP5	8128.0
H4C13	8117.0
ANAPC16	8064.0
CHMP4A	8022.0
H4C1	8017.0
PSMB1	7978.0
PSMA6	7971.0
CEP192	7966.0
TUBG2	7860.0
NUP98	7826.0
KNTC1	7772.0
SFI1	7760.0
CSNK2A1	7758.0
H2AC8	7728.0
PSME2	7675.0
ANAPC4	7652.0
PSMD1	7564.0
ANAPC5	7558.0
H2BC4	7539.0
MAPK3	7526.0
RPS27A	7499.0
LBR	7494.0
PSME1	7470.0
H3C1	7395.0
H2BC9	7228.5
H3C7	7228.5
CDC27	7198.0
DCTN1	7179.0
NEK6	7102.0
H4C8	7058.0
PSMA3	7039.0
MAD1L1	7020.0
PSMA1	6977.0
HAUS6	6964.0
PSMD6	6942.0
DSN1	6888.0
KIF18A	6886.0
GORASP2	6781.0
CDC16	6748.0
PRKCB	6744.0
NUP37	6708.0
PSMB3	6665.0
H3C10	6652.0
PSMD11	6649.0
CDK5RAP2	6570.0
PPP2R2D	6543.0
TPR	6489.0
RPS27	6477.0
PDS5A	6446.0
PSMD12	6422.0
PSMB6	6370.0
ACTR1A	6363.0
CEP57	6346.0
ANAPC10	6338.0
H2BC8	6334.0
NUP160	6322.0
NDE1	6318.0
GORASP1	6304.0
PSMD5	6295.0
PSME3	6289.0
CNEP1R1	6255.0
MAU2	6250.0
H2BC12	6220.0
PCM1	6109.0
CENPM	6069.0
CENPL	6013.0
CSNK2A2	5953.0
PSMD9	5939.0
H3C4	5911.0
PRKCA	5835.0
MAPK1	5826.0
ANAPC11	5794.0
VPS4A	5772.0
SEH1L	5744.0
ANKLE2	5726.0
CENPE	5720.0
CDC26	5692.0
CENPC	5654.0
CENPU	5624.0
CSNK2B	5559.0
PSMB2	5390.0
UBC	5385.0
NUP42	5371.0
ARPP19	5356.0
H4C3	5297.0
CENPK	5296.0
CEP164	5278.0
NIPBL	5277.0
H2AJ	5141.0
DYNC1LI1	5132.0
CENPQ	5131.0
CHMP7	5074.0
CEP131	5065.0
RAN	5055.0
PSMA7	5054.0
PPP2R5C	5016.0
EML4	4980.0
CLASP2	4967.0
RANBP2	4890.0
SEC13	4854.0
RCC1	4850.0
NUP214	4833.0
PLK4	4782.0
WAPL	4638.0
NCAPD3	4509.0
B9D2	4467.0
TUBB	4460.0
PSMA8	4378.0
CHMP6	4359.0
PPP2R1A	4310.0
KIF2A	4282.0
SGO2	4264.0
KIF2B	4249.0
TUBA4A	4239.0
RAB2A	4233.0
DYNLL1	4203.0
CEP43	4180.0
TUBB2A	4122.0
ODF2	4100.0
PSMC2	4047.0
H4C2	3987.0
PSMB10	3971.0
BUB3	3920.0
TUBB2B	3907.0
BUB1	3874.0
TUBA4B	3811.0
CENPO	3792.0
ANAPC7	3782.0
NEDD1	3777.0
CHMP3	3762.0
AKAP9	3759.0
ZWINT	3720.0
TNPO1	3709.0
TAOK1	3609.0
TUBGCP4	3597.0
H4C4	3596.0
H3C8	3521.0
NCAPG2	3483.0
PLK1	3472.0
UBE2E1	3470.0
H2AC20	3382.0
PSMC3	3323.0
NUP107	3276.0
CTDNEP1	3265.0
LEMD3	3263.0
KIF20A	3253.0
SDCCAG8	3232.0
PSMC1	3148.0
PSME4	3137.0
DCTN2	3135.0
HAUS4	3083.0
NDC1	3079.0
PSMC5	3065.0
H3-3B	3055.0
H2AC18	2954.5
H2AC19	2954.5
VRK2	2848.0
H2AC7	2792.5
H2BC7	2792.5
NEK2	2787.0
MIS12	2770.0
IST1	2752.0
H2BC21	2718.0
NUP188	2493.0
NUP35	2378.0
TUBB4B	2340.0
PPP1CC	2315.0
PSMB8	2300.0
H3-3A	2262.0
TUBG1	2186.0
KNL1	2176.0
CCNB1	2131.0
H2BC5	2100.0
POM121C	2036.0
MCPH1	2033.0
PSMD14	1903.0
UBE2S	1865.0
H2BC17	1857.0
H2BC13	1834.0
H3C2	1828.0
ENSA	1750.0
RAB1A	1737.0
PSMB11	1723.0
PPP2R5A	1572.0
SKA2	1570.0
CDK1	1360.0
RB1	1359.0
NDC80	1352.0
LMNB1	1327.0
H2BC11	1286.0
KIF23	1051.0
TUBA1A	1018.0
NUF2	899.0
AURKB	823.0
CCP110	730.0
RAB1B	655.0
NEK9	629.0
CDC20	611.0
PDS5B	610.0
NUP43	561.0
PPP2CB	497.0
NEK7	489.0
SMC4	404.0
NUP205	331.0
PPP2R5B	256.0
LPIN1	218.0
TUBB6	150.0
USO1	135.0
CCNB2	97.0
KPNB1	32.0
PPP2R5E	-53.0
TMPO	-93.0
MAPRE1	-157.0
H4C9	-276.0
TUBB4A	-357.0
TUBA8	-372.0
H2AX	-614.0
FBXO5	-747.0
NME7	-869.0
KIF2C	-1021.0
CEP78	-1096.0
SSNA1	-1130.0
ANAPC2	-1206.0
CEP76	-1238.0
CENPA	-1250.0
UBE2D1	-1471.0
CEP70	-1485.0
HAUS1	-1510.0
PPP2R2A	-1648.0
ITGB3BP	-1974.0
CENPT	-2031.0
LPIN2	-2041.0
PTTG1	-2060.0
PPP2CA	-2084.0
UBA52	-2237.0
CEP41	-2263.0
UBB	-2335.0
NCAPG	-2420.0
MAD2L1	-2478.0
ZW10	-2497.0
HAUS3	-2507.0
NUP153	-2541.0
CENPH	-2615.0
DYNC1I2	-2797.0
TUBGCP5	-2825.0
H2BC26	-2895.0
PSMB9	-2938.0
ALMS1	-3091.0
CEP135	-3106.0
NUP155	-3213.0
RAD21	-3318.0
HSP90AA1	-3488.0
SUMO1	-3539.0
TUBA3D	-3545.0
TUBA1C	-3556.0
H2AZ2	-3800.0
UBE2C	-3845.0
TUBB3	-4002.0
SPC25	-4088.0
PSMA5	-4331.0
H2BC1	-4453.0
SKA1	-4482.0
BIRC5	-4539.0
TUBA3E	-4662.0
H3C6	-4925.0
VRK1	-4983.0
NCAPH	-5000.0
PSMD8	-5050.0
HAUS2	-5154.0
DYNC1I1	-5334.0
H2AC14	-5418.0
LPIN3	-5512.0
SPDL1	-5533.0
H3-4	-5699.0
H2BC3	-5733.0
NINL	-5777.0
H4C16	-5871.0
TUBA1B	-6340.0
TUBB1	-6519.0
MZT1	-6533.0
H3C3	-6688.0
LMNA	-6774.0
CHMP4C	-6820.0
H2BC14	-7035.0
H4C12	-7199.0
TUBA3C	-7269.0
TUBAL3	-7278.0
SEM1	-7461.0
SPC24	-7608.0
H3C12	-7844.0
PRKAR2B	-7999.0
MZT2B	-8863.0
TUBB8	-8942.0

---

REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA

REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA

	1146
set	REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA
setSize	263
pANOVA	6.9e-20
s.dist	0.327
p.adjustANOVA	1.26e-17

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PRPF8	11964
POLR2J	11816
METTL14	11687
SF1	11613
POLR2A	11407
POLR2E	11395
LSM4	11287
METTL3	11240
ZC3H11A	11183
DHX16	11089
PPIH	11075
HNRNPM	11071
NXF1	11039
SF3A3	11001
CCDC12	10921
GLE1	10891
RAE1	10890
CPSF6	10847
SYMPK	10822
RBM42	10732

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PRPF8	11964
POLR2J	11816
METTL14	11687
SF1	11613
POLR2A	11407
POLR2E	11395
LSM4	11287
METTL3	11240
ZC3H11A	11183
DHX16	11089
PPIH	11075
HNRNPM	11071
NXF1	11039
SF3A3	11001
CCDC12	10921
GLE1	10891
RAE1	10890
CPSF6	10847
SYMPK	10822
RBM42	10732
PPIL2	10648
PRPF38A	10583
PRPF18	10560
SUGP1	10559
POLDIP3	10549
NUP210	10455
CPSF1	10403
FAM32A	10379
RBM5	10311
POLR2B	10306
TFIP11	10299
MAGOH	10284
SNRNP70	10173
NUP62	10167
SRRM2	10082
NUP85	10023
CHERP	9969
SNRPD2	9957
PUF60	9935
NUP54	9855
PRPF19	9844
XAB2	9792
DHX38	9776
SNRPN	9640
ZMAT5	9637
U2AF2	9577
YJU2	9562
CPSF4	9551
HNRNPC	9537
NUP88	9522
SNRPB	9514
NUP133	9347
WBP4	9229
PRKRIP1	9222
FUS	9191
SNRPC	9188
DHX35	9177
PRPF6	9169
ALYREF	9167
DDX42	9106
MAGOHB	9064
LSM7	9054
SRRM1	9051
SRRT	8722
U2SURP	8710
SMU1	8708
GTF2F1	8571
BCAS2	8514
NUP93	8494
POLR2H	8450
WDR33	8448
THOC5	8319
POM121	8233
CPSF2	8224
NUP50	8160
AAAS	8159
NUP58	8140
CLP1	8113
SNRNP40	8019
SF3B3	8015
DHX8	7997
HNRNPA2B1	7955
BUD31	7838
NUP98	7826
DHX15	7710
TRA2B	7660
ZMAT2	7420
PABPN1	7394
PPIL3	7267
LENG1	7253
NCBP2	7200
CTNNBL1	7140
SNRNP200	7133
SF3A1	7119
SARNP	7085
HNRNPK	7040
SF3B1	6993
CRNKL1	6918
PCBP1	6906
PPIE	6843
ISY1	6808
NUP37	6708
SAP18	6685
THOC1	6626
NUDT21	6619
DDX39A	6564
SRSF9	6509
HSPA8	6500
SF3B5	6491
TPR	6489
LSM5	6394
SNRNP35	6383
RBM22	6330
NUP160	6322
PCBP2	6238
DDX41	6050
CDC40	6019
DDX23	6002
SEH1L	5744
SRSF4	5719
RBM8A	5667
PPP1R8	5660
CWC22	5540
SLU7	5533
CACTIN	5479
NUP42	5371
SF3A2	5350
POLR2I	5214
PCF11	5207
POLR2G	4982
UBL5	4931
RANBP2	4890
HNRNPL	4884
SNIP1	4872
SEC13	4854
NUP214	4833
DHX9	4737
CSTF2T	4633
POLR2F	4630
CWC25	4619
BUD13	4481
THOC6	4417
RNPC3	4386
SRSF6	4301
WDR70	4297
PRPF4	4243
FYTTD1	4186
SNRPF	4099
PNN	3997
MFAP1	3988
SRSF11	3965
SNRPE	3915
LSM3	3863
IK	3839
WBP11	3834
HNRNPD	3781
HNRNPA1	3775
HNRNPU	3733
SNRPD3	3606
TCERG1	3568
HNRNPR	3555
PDCD7	3497
EIF4E	3463
NUP107	3276
POLR2D	3258
MTREX	3213
SRSF1	3201
PRPF31	3198
NDC1	3079
PPIG	2920
SART1	2847
SNRNP48	2803
SMNDC1	2785
ACIN1	2707
SRSF5	2693
PPIL1	2651
DDX39B	2621
GCFC2	2535
NUP188	2493
CPSF3	2435
NUP35	2378
CDC5L	2274
SNRPA1	2271
SRSF3	2267
THOC3	2255
SNRPD1	2163
NSRP1	2065
POM121C	2036
LUC7L3	1957
CSTF3	1908
SNRPG	1899
HNRNPF	1897
CWC15	1872
RBM17	1870
DDX5	1755
SF3B2	1722
SDE2	1612
DDX46	1605
RBM39	1598
PRPF3	1597
RBM25	1564
PPWD1	1484
THOC7	1471
PTBP1	1402
PRPF40A	1393
SNRNP25	1361
CASC3	1351
U2AF1L4	1290
SRSF12	1262
ZNF830	1115
LSM6	951
CPSF7	901
C9orf78	789
NUP43	561
HNRNPA3	428
PPIL4	417
LSM8	333
NUP205	331
PAPOLA	320
CSTF1	299
CCAR1	199
LSM2	163
EIF4A3	121
CWC27	91
AQR	42
NCBP1	-175
TXNL4A	-184
CHTOP	-280
CWF19L2	-492
SNRPB2	-564
HNRNPH1	-594
EFTUD2	-937
ZCRB1	-1100
SNRPA	-1139
YBX1	-1287
GTF2F2	-1392
SRSF7	-1396
SNU13	-1463
DNAJC8	-1502
NXT1	-1557
GPATCH1	-1626
POLR2L	-1678
USP39	-1751
RBM7	-1970
SF3B4	-2190
WTAP	-2436
NUP153	-2541
SYF2	-2735
SRSF10	-2873
SRSF2	-3015
SLBP	-3174
NUP155	-3213
FIP1L1	-3399
PLRG1	-3701
POLR2K	-3852
RNPS1	-3954
PRCC	-4201
SNW1	-4266
PHF5A	-4818
POLR2C	-6018
SF3B6	-6121
SNRNP27	-6233
SRSF8	-8657

---

REACTOME_CELLULAR_RESPONSES_TO_STIMULI

REACTOME_CELLULAR_RESPONSES_TO_STIMULI

	1314
set	REACTOME_CELLULAR_RESPONSES_TO_STIMULI
setSize	779
pANOVA	1.88e-18
s.dist	0.184
p.adjustANOVA	3.08e-16

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PREB	12151
P4HB	12090
FLCN	11915
LAMTOR3	11769
NPRL3	11766
CREBBP	11715
ATP6V0D1	11665
ATP6V0E2	11626
SOD3	11622
CEBPB	11589
TLN1	11588
H2BC15	11524
TFDP1	11506
H4C5	11447
DYNLL2	11413
ATP6V0C	11372
AGO1	11345
RPL32	11326
H2BC6	11322
GPX7	11314

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PREB	12151.0
P4HB	12090.0
FLCN	11915.0
LAMTOR3	11769.0
NPRL3	11766.0
CREBBP	11715.0
ATP6V0D1	11665.0
ATP6V0E2	11626.0
SOD3	11622.0
CEBPB	11589.0
TLN1	11588.0
H2BC15	11524.0
TFDP1	11506.0
H4C5	11447.0
DYNLL2	11413.0
ATP6V0C	11372.0
AGO1	11345.0
RPL32	11326.0
H2BC6	11322.0
GPX7	11314.0
FZR1	11268.0
IDH1	11194.0
MINK1	11119.0
PSMB4	11076.0
EIF2AK3	11069.0
SYVN1	11054.0
NCOR2	11049.0
CABIN1	11042.0
MTOR	11011.0
DEPDC5	10964.0
MEF2D	10950.0
CEBPG	10948.0
SERPINH1	10913.0
DCTN3	10909.0
TKT	10905.0
PLA2G4B	10902.0
GSTP1	10897.0
RPS19BP1	10894.0
PSMD4	10893.0
RAE1	10890.0
ATF4	10878.0
NPLOC4	10876.0
PSMD13	10870.0
H2AZ1	10867.0
MAPKAPK3	10859.0
ARFGAP1	10813.0
USP46	10792.0
HSBP1	10737.0
PSMA2	10707.0
DNAJA4	10682.0
TRIB3	10681.0
DYNC1H1	10679.0
YWHAE	10677.0
RPA1	10676.0
HM13	10673.0
GPX2	10608.0
NOTCH1	10585.0
RPL26	10573.0
WDR24	10558.0
EXOSC6	10554.0
ELOB	10535.0
CAMK2G	10508.0
DDX11	10505.0
MAFG	10481.0
CDC23	10475.0
COX16	10473.0
ANAPC15	10466.0
NUP210	10455.0
ATP6V1G1	10450.0
PSMC6	10418.0
ZBTB17	10385.0
SZT2	10384.0
MUL1	10314.0
TINF2	10303.0
NPRL2	10245.0
CRYBA4	10234.0
EXOSC7	10219.0
NCOR1	10213.0
NUP62	10167.0
EXOSC2	10153.0
CREB3L2	10148.0
ID1	10132.0
MED1	10131.0
DYNC1LI2	10120.0
RPS9	10077.0
PARN	10060.0
COX6B1	10052.0
NUP85	10023.0
TACO1	10013.0
PSMD3	9979.0
HSPA4L	9972.0
ATP6V1D	9871.0
ETS1	9857.0
NUP54	9855.0
EGLN2	9842.0
UBN1	9807.0
PSMD7	9804.0
AKT1	9802.0
DNAJC7	9801.0
COX14	9790.0
MRPL18	9789.0
RPL6	9786.0
DDIT3	9785.0
COX8A	9775.0
HSPA9	9718.0
PSMC4	9692.0
CRTC1	9690.0
RPTOR	9678.0
KDELR3	9657.0
ANAPC1	9651.0
MAFK	9633.0
ATP6V0E1	9625.0
RPL27A	9619.0
PSMD2	9598.0
LAMTOR1	9581.0
ADD1	9566.0
TATDN2	9557.0
NUP88	9522.0
NFYA	9507.0
PTGES3	9495.0
H2AC4	9477.0
PSMB5	9461.0
YIF1A	9460.0
TNRC6C	9415.0
RPL19	9400.0
EP300	9390.0
CDKN1B	9381.0
NUP133	9347.0
BTRC	9324.0
TXN2	9280.0
RPL34	9275.0
PRKCD	9271.0
NDUFA4	9254.0
RPL14	9168.0
EP400	9151.0
RPL41	9118.0
MYDGF	9089.0
H4C6	9077.0
IL1A	9007.0
PSMF1	9002.0
LAMTOR4	8940.0
H3C11	8908.0
H2BC10	8901.0
XPO1	8891.0
NCOA6	8865.0
TFDP2	8744.0
RPLP1	8728.0
PPARA	8725.0
CREB1	8716.0
MAP2K6	8671.0
PDIA5	8656.0
EIF2AK1	8621.0
COX19	8609.0
TPP1	8594.0
PSMB7	8555.0
LY96	8508.0
NUP93	8494.0
PSMA4	8487.0
AKT2	8422.0
TALDO1	8385.0
CARM1	8334.0
CRTC2	8332.0
EHMT1	8321.0
H2AC6	8277.0
H4C11	8241.0
POM121	8233.0
RPS15	8218.0
CREB3L4	8204.0
NUP50	8160.0
AAAS	8159.0
UFD1	8151.0
NUP58	8140.0
GPX3	8136.0
H4C13	8117.0
DNAJB1	8073.0
ANAPC16	8064.0
RPL22	8037.0
H4C1	8017.0
PSMB1	7978.0
PSMA6	7971.0
GSK3A	7969.0
CAPZB	7951.0
AQP8	7898.0
BLVRA	7834.0
GSR	7831.0
NUP98	7826.0
RHEB	7765.0
CSNK2A1	7758.0
ATF5	7744.0
H2AC8	7728.0
CYBA	7724.0
DCTN4	7680.0
PSME2	7675.0
ANAPC4	7652.0
DCTN6	7640.0
TNRC6A	7634.0
ACTR10	7623.0
DEDD2	7606.0
PSMD1	7564.0
ANAPC5	7558.0
H2BC4	7539.0
MAPK3	7526.0
HSF1	7500.0
RPS27A	7499.0
FNIP1	7492.0
HSPA1L	7476.0
MAPK9	7473.0
PSME1	7470.0
HMOX1	7469.0
HYOU1	7463.0
TXNIP	7462.0
ATF6	7452.0
GCLC	7444.0
H3C1	7395.0
CAT	7326.0
NUDT2	7284.0
RPS23	7245.0
H2BC9	7228.5
H3C7	7228.5
EHMT2	7223.0
RPS10	7219.0
CDC27	7198.0
DCTN1	7179.0
CXXC1	7145.0
COX5A	7138.0
MTF1	7079.0
DNAJC2	7069.0
MBTPS1	7060.0
H4C8	7058.0
PSMA3	7039.0
CTDSP2	7032.0
EXOSC5	7024.0
PSMA1	6977.0
RAI1	6970.0
WIPI1	6947.0
PSMD6	6942.0
CDKN2D	6927.0
PDIA6	6923.0
HMOX2	6885.0
TERF2IP	6812.0
GCN1	6810.0
RPS20	6789.0
TCIRG1	6757.0
CDC16	6748.0
FNIP2	6741.0
NUP37	6708.0
PSMB3	6665.0
PHC2	6654.0
H3C10	6652.0
CUL7	6650.0
PSMD11	6649.0
ATP6V1A	6629.0
SLC46A1	6578.0
MAP2K7	6577.0
BAG2	6550.0
HSPA8	6500.0
TPR	6489.0
RPS27	6477.0
CLOCK	6442.0
PSMD12	6422.0
EIF2S1	6395.0
PSMB6	6370.0
FABP1	6369.0
COX6C	6367.0
ACTR1A	6363.0
CCAR2	6342.0
ANAPC10	6338.0
H2BC8	6334.0
SURF1	6325.0
NUP160	6322.0
HSPH1	6303.0
PSMD5	6295.0
PSME3	6289.0
WDR59	6261.0
H2BC12	6220.0
NR1D1	6211.0
ATF3	6194.0
SHC1	6186.0
RING1	6185.0
RPS2	6180.0
IL6	6166.0
RPS15A	6160.0
MDM4	6157.0
TNRC6B	6144.0
MYC	6135.0
EPAS1	6126.0
CBX4	6103.0
RELA	6020.0
RPS16	6017.0
RPL15	5994.0
CITED2	5977.0
CRTC3	5970.0
CSNK2A2	5953.0
PSMD9	5939.0
H3C4	5911.0
EXTL3	5890.0
CLEC1B	5882.0
RPL11	5878.0
MAPK1	5826.0
HIF1AN	5806.0
GSK3B	5797.0
ANAPC11	5794.0
SEH1L	5744.0
SIN3A	5710.0
CDC26	5692.0
EIF2S2	5673.0
SEC31A	5671.0
ABCC1	5652.0
DNAJC3	5642.0
JUN	5629.0
E2F3	5600.0
SUZ12	5592.0
PRDX5	5581.0
CSNK2B	5559.0
SIN3B	5452.0
EDEM1	5411.0
HDAC3	5406.0
PSMB2	5390.0
UBC	5385.0
RPL35A	5375.0
NUP42	5371.0
GCLM	5366.0
MT2A	5353.0
BMI1	5313.0
H4C3	5297.0
HSPB1	5239.0
CBX8	5208.0
RPA2	5194.0
MT1M	5187.0
MAPK14	5180.0
TXNRD2	5164.0
H2AJ	5141.0
DYNC1LI1	5132.0
DIS3	5080.0
ATP6V1F	5076.0
MDM2	5073.0
SRPRB	5057.0
PSMA7	5054.0
KAT5	5000.0
AKT1S1	4918.0
RXRA	4895.0
RANBP2	4890.0
SEC13	4854.0
NFYC	4842.0
NUP214	4833.0
PHC3	4783.0
LIMD1	4754.0
HERPUD1	4667.0
DCTN5	4586.0
NFYB	4583.0
HELZ2	4581.0
STIP1	4556.0
SCMH1	4529.0
SQSTM1	4520.0
BAG1	4518.0
SLC7A11	4510.0
RPL29	4480.0
SSR1	4444.0
KDM6B	4437.0
RPS14	4403.0
DPP3	4384.0
PSMA8	4378.0
RPL28	4311.0
UBE2D3	4277.0
BMAL1	4261.0
TUBA4A	4239.0
DYNLL1	4203.0
PPARGC1A	4184.0
ITFG2	4169.0
SRXN1	4153.0
TUBB2A	4122.0
ARNT	4094.0
CYCS	4068.0
PSMC2	4047.0
CUL1	4015.0
H4C2	3987.0
PSMB10	3971.0
RPL31	3951.0
RPS3A	3917.0
DNAJB6	3916.0
TUBB2B	3907.0
MT1E	3891.0
RBBP4	3878.0
BLVRB	3862.0
TERF1	3831.0
TUBA4B	3811.0
PHC1	3804.0
ANAPC7	3782.0
SKP1	3705.0
HSP90AB1	3700.0
ATP6V1E1	3663.0
MAP4K4	3637.0
CHD9	3604.0
H4C4	3596.0
MRE11	3571.0
MAPKAPK5	3566.0
H3C8	3521.0
RPL35	3510.0
TP53	3499.0
UBE2E1	3470.0
H1-5	3468.0
AGO3	3420.0
H2AC20	3382.0
PSMC3	3323.0
HSPA14	3285.0
NUP107	3276.0
RPL18	3205.0
CASTOR1	3187.0
RPL9	3178.0
RPS29	3176.0
RPS24	3174.0
PSMC1	3148.0
RPA3	3146.0
HSPA6	3145.0
PSME4	3137.0
DCTN2	3135.0
DCP2	3108.0
COX7A2L	3104.0
CAPZA1	3088.0
NDC1	3079.0
PSMC5	3065.0
H3-3B	3055.0
ATP6V1H	3050.0
COX4I1	3049.0
LRPPRC	3047.0
MIOS	2994.0
GPX1	2970.0
MT1F	2960.0
H2AC18	2954.5
H2AC19	2954.5
HIGD1A	2925.0
TERF2	2921.0
CUL3	2861.0
ELOC	2833.0
BAG4	2831.0
CBX2	2819.0
H2AC7	2792.5
H2BC7	2792.5
CREB3	2783.0
BRCA1	2780.0
HSPA1A	2773.0
CREB3L3	2771.0
NCF2	2756.0
NCOA2	2754.0
H2BC21	2718.0
EXTL2	2653.0
RPL21	2628.0
NCF4	2618.0
DNAJA2	2578.0
DCSTAMP	2545.0
KLHDC3	2531.0
NUP188	2493.0
RPS3	2461.0
COX11	2459.0
EXOSC9	2431.0
CDKN1A	2387.0
HDGF	2381.0
NUP35	2378.0
RPL4	2357.0
COX6A1	2351.0
TUBB4B	2340.0
RPS27L	2306.0
PSMB8	2300.0
AJUBA	2275.0
CDK4	2268.0
H3-3A	2262.0
PRDX1	2226.0
RPL10A	2208.0
RPL12	2178.0
ATR	2151.0
ATM	2137.0
H2BC5	2100.0
PRDX3	2089.0
RRAGA	2063.0
TXN	2053.0
TXNRD1	2049.0
EXOSC8	2045.0
POM121C	2036.0
RPS6KA2	2023.0
WTIP	2012.0
CREBRF	2008.0
COX5B	1997.0
HSPA12B	1920.0
PSMD14	1903.0
UBE2S	1865.0
BMT2	1859.0
H2BC17	1857.0
H2BC13	1834.0
H3C2	1828.0
DNAJB9	1805.0
TGS1	1787.0
RPL13A	1771.5
SESN1	1738.0
PSMB11	1723.0
KEAP1	1708.0
CALR	1632.0
MAP1LC3B	1577.0
UBE2D2	1556.0
FAU	1541.0
SIRT1	1473.0
RPL36	1472.0
H1-0	1385.0
H1-4	1364.0
BAG5	1363.0
RB1	1359.0
SERP1	1345.0
RPS21	1329.0
LMNB1	1327.0
H2BC11	1286.0
NCOA1	1280.0
STAT3	1277.0
HSPA13	1165.0
MOV10	1158.0
PALB2	1148.0
RPL37	1116.0
ST13	1071.0
MIR24-1	1070.0
H1-2	1036.0
TUBA1A	1018.0
RPS18	992.0
VCP	920.0
RPL30	897.0
NFE2L2	886.0
MLST8	854.0
EED	774.0
EIF2AK4	716.0
CAPZA2	668.0
HIRA	630.0
EXOSC1	625.0
CBX6	622.0
NLRP3	615.0
ACADVL	609.0
NUP43	561.0
CDKN2C	549.0
HSP90B1	545.0
RPS6	524.0
AKT3	516.0
RPS7	463.0
CCL2	429.0
DNAJA1	367.0
NUP205	331.0
ATP6V1G2	278.0
PPP2R5B	256.0
UBXN7	254.0
TBL1XR1	245.0
CDKN2A	229.0
ERN1	198.0
ATP6V0B	176.0
GFPT1	169.0
EGLN1	164.0
TUBB6	150.0
KICS2	132.0
TNIK	113.0
TLR4	104.0
CDK6	85.0
HBA2	84.0
COX7C	-37.0
TRIM21	-70.0
XBP1	-87.0
CHAC1	-114.0
ATP6V1B2	-200.0
RPL18A	-240.0
RPL23	-261.0
RPL27	-270.0
H4C9	-276.0
MAP3K5	-283.0
APOA1	-340.0
TUBB4A	-357.0
TUBA8	-372.0
RRAGD	-414.0
ATOX1	-422.0
RPLP0	-487.0
FBXL17	-532.0
H2AX	-614.0
SNCB	-617.0
DNAJB11	-642.0
ALB	-650.0
STAP2	-651.0
VHL	-675.0
NBN	-689.0
BAG3	-711.0
SP1	-714.0
MAPK7	-727.0
HSPA5	-841.0
SKP2	-864.0
GML	-867.0
EZH2	-873.0
HIKESHI	-1003.0
NOX4	-1026.0
ERO1A	-1028.0
RPS6KA1	-1030.0
VEGFA	-1084.0
SCO1	-1148.0
ERF	-1154.0
FOS	-1163.0
CUL2	-1184.0
EXOSC4	-1198.0
ANAPC2	-1206.0
MAP2K4	-1231.0
HSPA2	-1245.0
EXTL1	-1258.0
RAD50	-1348.0
HSPA4	-1415.0
EEF1A1	-1425.0
MAPK8	-1441.0
NPAS2	-1464.0
UBE2D1	-1471.0
PRDX2	-1476.0
HSPB8	-1534.0
RPS13	-1554.0
MAP2K3	-1689.0
POT1	-1694.0
FKBP4	-1761.0
ATP6V1C1	-1901.0
EXOSC3	-1962.0
MT1G	-1999.0
MAPKAPK2	-2022.0
GPX5	-2058.0
RRAGC	-2062.0
NOX5	-2111.0
NQO1	-2121.0
ACD	-2160.5
RPL26L1	-2195.0
RPSA	-2216.0
RBX1	-2227.0
UBA52	-2237.0
RPL7	-2286.0
CDK2	-2309.0
UBB	-2335.0
RNF2	-2391.0
RPS5	-2392.0
NUP153	-2541.0
ETS2	-2578.0
RPS28	-2610.0
RPL36AL	-2643.5
RORA	-2774.0
DYNC1I2	-2797.0
SRPRA	-2817.0
GPX6	-2824.0
NR3C1	-2846.0
H2BC26	-2895.0
RPS12	-2916.0
PSMB9	-2938.0
ATP6V1C2	-2944.0
CCNE1	-2947.0
RLN1	-2969.5
E2F2	-3008.0
ME1	-3027.0
PTK6	-3078.0
MEF2C	-3189.0
SESN2	-3193.0
ASNS	-3199.0
NUP155	-3213.0
GRB10	-3246.0
RPL22L1	-3311.0
CDKN2B	-3314.0
COX18	-3348.0
IGFBP7	-3353.0
CCNE2	-3373.0
LAMTOR5	-3417.0
HSP90AA1	-3488.0
RPL39L	-3504.0
SH3BP4	-3525.0
TUBA3D	-3545.0
TUBA1C	-3556.0
SLC38A9	-3577.0
NR3C2	-3588.0
CREB3L1	-3595.0
FKBP5	-3607.0
ATF2	-3617.0
FKBP14	-3637.0
TNFRSF21	-3656.0
CSRP1	-3666.0
RPL5	-3668.0
NFKB1	-3689.0
BACH1	-3711.0
H2AZ2	-3800.0
MAPK11	-3828.0
UBE2C	-3845.0
COX20	-3906.0
TUBB3	-4002.0
ATP6V1E2	-4008.0
RPS11	-4060.0
CCNA1	-4120.0
RPL3L	-4134.0
MT1H	-4146.0
RPS19	-4241.0
SOD2	-4248.0
CCS	-4259.0
SOD1	-4277.0
H1-1	-4307.0
PSMA5	-4331.0
MT1X	-4370.0
RPL17	-4430.0
H2BC1	-4453.0
CRYAB	-4471.0
RPL3	-4491.0
RPLP2	-4579.0
HIF1A	-4580.0
TUBA3E	-4662.0
SCO2	-4677.0
RPL7A	-4734.0
ATP6V1G3	-4835.0
CAMK2D	-4902.0
H3C6	-4925.0
RPL23A	-4959.0
PSMD8	-5050.0
HMGA2	-5096.0
AGO4	-5113.0
CAMK2B	-5202.0
HSPA12A	-5205.0
GPX8	-5264.0
HSPA1B	-5266.0
GOSR2	-5270.0
IFNB1	-5278.0
RPL10L	-5285.0
MT1A	-5312.0
DYNC1I1	-5334.0
PRDX6	-5370.0
H1-3	-5401.0
H2AC14	-5418.0
RPL24	-5518.0
WFS1	-5554.0
H3-4	-5699.0
H2BC3	-5733.0
H4C16	-5871.0
KHSRP	-5893.0
MT1B	-5934.0
CCNA2	-5945.0
SMARCD3	-6048.0
PGD	-6138.0
RPL38	-6279.0
RPL13	-6322.0
TUBA1B	-6340.0
RPL8	-6372.0
EGLN3	-6449.0
RPS8	-6455.0
TUBB1	-6519.0
ATP6V1B1	-6623.0
KPTN	-6665.0
RPS25	-6687.0
H3C3	-6688.0
LMNA	-6774.0
PGR	-6783.0
H2BC14	-7035.0
RPL37A	-7080.0
H4C12	-7199.0
LAMTOR2	-7256.0
TUBA3C	-7269.0
HIF3A	-7272.0
TUBAL3	-7278.0
PPP1R15A	-7308.0
NRIP1	-7332.0
CAMK2A	-7340.0
IMPACT	-7453.0
SEM1	-7461.0
ATP6V0D2	-7515.0
GSTA3	-7569.0
HMGA1	-7614.0
EPO	-7676.0
H3C12	-7844.0
CA9	-8166.0
CXCL8	-8180.0
MAPK10	-8203.0
E2F1	-8231.0
APOB	-8243.0
HSPB2	-8292.0
VENTX	-8322.0
MIR24-2	-8446.0
RPS26	-8718.0
HBB	-8725.0
GSTA1	-8741.0
CAPZA3	-8836.0
TUBB8	-8942.0
ASF1A	-9011.0
MT4	-9097.0
HBA1	-9321.0
MT3	-9352.0
IGFBP1	-9400.0

---

REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

	1024
set	REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION
setSize	1356
pANOVA	8.74e-18
s.dist	0.139
p.adjustANOVA	1.24e-15

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PREB	12151
P4HB	12090
B3GNT8	12048
AMDHD2	12042
PDIA3	12004
RNF123	11967
SATB1	11928
TAB1	11909
MAN2A2	11884
PIAS4	11883
CSNK1D	11871
CHML	11857
AXIN1	11805
WDR20	11739
SUMO3	11735
NRN1L	11716
CREBBP	11715
TADA2B	11706
MGAT5	11655
DPH7	11620

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PREB	12151.0
P4HB	12090.0
B3GNT8	12048.0
AMDHD2	12042.0
PDIA3	12004.0
RNF123	11967.0
SATB1	11928.0
TAB1	11909.0
MAN2A2	11884.0
PIAS4	11883.0
CSNK1D	11871.0
CHML	11857.0
AXIN1	11805.0
WDR20	11739.0
SUMO3	11735.0
NRN1L	11716.0
CREBBP	11715.0
TADA2B	11706.0
MGAT5	11655.0
DPH7	11620.0
GANAB	11567.0
NR1H2	11561.0
FBXW12	11548.0
TRAPPC10	11541.0
CD52	11540.0
LY6G6D	11535.0
COMMD8	11531.0
H2BC15	11524.0
RANGAP1	11517.0
MBD6	11516.0
EEF1AKMT1	11462.0
FBXL14	11460.0
H4C5	11447.0
RNF144A	11434.0
INCENP	11431.0
PIGL	11427.0
DYNLL2	11413.0
SEC22A	11390.0
H2BC6	11322.0
TGFBR1	11304.0
ABRAXAS2	11288.0
APOA2	11286.0
USP22	11278.0
SEC24B	11267.0
TTLL12	11261.0
UBE2F	11232.0
YKT6	11228.0
RFT1	11224.0
ADAMTS4	11220.0
MTA1	11188.0
ST3GAL1	11158.0
PIGS	11150.0
TGFB1	11148.0
UBE2I	11138.0
FOXK2	11092.0
PSMB4	11076.0
TTL	11068.0
SYVN1	11054.0
UBA2	11051.0
NCOR2	11049.0
SELENOS	11048.0
GLB1	11043.0
KLHL42	11033.0
USP5	11026.0
HDAC4	11016.0
PPP6C	11008.0
RTF1	11007.0
METTL22	11006.0
ALG12	10993.0
SKIC8	10984.0
ST6GALNAC4	10981.0
FBXW10	10958.0
PROC	10942.0
PIGO	10937.0
USP7	10931.0
DCTN3	10909.0
UBE2V2	10901.0
PSMD4	10893.0
RAE1	10890.0
CHD3	10888.0
NPLOC4	10876.0
PSMD13	10870.0
VASH2	10860.0
CTSZ	10840.0
ARFGAP1	10813.0
EEF2	10808.0
MPDU1	10806.0
USP20	10779.0
KDM1B	10773.0
B4GALT4	10757.0
RNF181	10756.0
RCE1	10746.0
DAXX	10716.0
PSMA2	10707.0
DYNC1H1	10679.0
RPA1	10676.0
B4GAT1	10671.0
UBE2R2	10667.0
RAB11B	10646.0
ARRB2	10636.0
DCAF7	10620.0
ALG2	10619.0
H2AC15	10614.0
PARP1	10610.0
YY1	10609.0
UBXN1	10582.0
GNE	10571.0
ELOB	10535.0
COG1	10467.0
NUP210	10455.0
RPN1	10453.0
TPST2	10430.0
PSMC6	10418.0
COPA	10390.0
CTBP1	10335.0
B3GNT5	10330.0
GMPPA	10323.0
RAB5C	10317.0
MUL1	10314.0
LMAN2	10309.0
DCUN1D2	10300.0
C1GALT1	10281.0
FBXO4	10256.0
NAPA	10236.0
KLHL22	10192.0
GCNT7	10176.0
FCSK	10174.0
CDCA8	10170.0
NUP62	10167.0
ALG11	10165.0
RNF135	10134.0
HLTF	10124.0
DYNC1LI2	10120.0
ST6GAL1	10106.0
OTULIN	10081.0
DOHH	10069.0
MCRS1	10068.0
FOXK1	10047.0
CSF1	10036.0
NUP85	10023.0
DCUN1D1	9999.0
FBXW9	9987.0
PSMD3	9979.0
FBXO10	9971.0
F2	9951.0
OTUD3	9950.0
LAMB2	9940.0
RIPK1	9907.0
RNF40	9896.0
ASB1	9894.0
FBXL18	9869.0
FBXO7	9868.0
PIGN	9863.0
NUP54	9855.0
RAB25	9837.0
H2AC12	9830.0
PSMD7	9804.0
USP18	9787.0
RIPK2	9756.0
DDA1	9704.0
C4A	9699.5
PSMC4	9692.0
RAB23	9681.0
KDELR3	9657.0
QSOX1	9634.0
ASB7	9628.0
RAB40C	9618.0
SMAD7	9613.0
UAP1	9602.0
SMURF2	9601.0
PSMD2	9598.0
MRTFA	9588.0
WDR5	9587.0
ART3	9584.0
COPG1	9572.0
GOLGA2	9561.0
MGAT1	9560.0
GALNT6	9558.0
CUL9	9542.0
HNRNPC	9537.0
FBXL3	9531.0
NUP88	9522.0
GALNT12	9521.0
PNPLA2	9509.0
UBE2L3	9504.0
CALU	9479.0
H2AC4	9477.0
PSMB5	9461.0
CDC73	9451.0
RAB21	9447.0
RABGGTA	9443.0
FBXL22	9441.0
RPN2	9419.0
ST3GAL2	9407.0
POMK	9395.0
EP300	9390.0
ACTR8	9367.0
CD59	9356.0
LHB	9354.0
NUP133	9347.0
INO80	9340.0
BTRC	9324.0
TDG	9316.0
KAT2B	9295.0
RAB7A	9267.0
RCN1	9250.0
SEC24C	9238.0
ALG3	9228.0
UIMC1	9223.0
KBTBD7	9221.0
TRRAP	9187.0
BPIFB2	9153.0
STT3A	9152.0
TADA3	9149.0
NUS1	9143.0
GCNT1	9140.0
ST6GALNAC2	9138.0
MLEC	9119.0
HERC2	9108.0
CALM1	9105.0
ADRM1	9099.0
RAB44	9081.0
H4C6	9077.0
RAB8A	9068.0
DTL	9049.0
COMMD9	9046.0
COMMD6	9035.0
RNF103	9025.0
CD55	9018.0
RAD52	9016.0
PSMF1	9002.0
SEC23IP	8993.0
COPE	8985.0
PMM1	8982.0
DERL1	8974.0
MGAT4A	8966.0
PEX14	8927.0
FURIN	8913.0
H2BC10	8901.0
TEX101	8873.0
SUMF1	8829.0
STAG1	8828.0
COMMD5	8801.0
SENP5	8763.0
SAFB	8760.0
DCAF4	8759.0
H2AC11	8737.0
PPARA	8725.0
USP42	8692.0
COPS2	8678.0
MAVS	8672.0
RAD18	8649.0
BABAM1	8603.0
JOSD1	8562.0
HGS	8560.0
MAN2A1	8557.0
PSMB7	8555.0
GCNT3	8532.0
TMED10	8519.0
KAT2A	8511.0
COPS6	8496.0
NUP93	8494.0
PSMA4	8487.0
WDTC1	8484.0
ALG9	8483.0
SEC16A	8479.0
GOLM1	8477.0
CTSA	8444.0
PRKCSH	8430.0
LYPD4	8420.0
ALG5	8419.0
VCPKMT	8408.0
FUT3	8394.0
ACTL6A	8382.0
FN3KRP	8344.0
B4GALT3	8341.0
ASB3	8291.0
ANO8	8288.0
H2AC6	8277.0
H4C11	8241.0
PML	8234.0
POM121	8233.0
SMC3	8217.0
NUP50	8160.0
AAAS	8159.0
UFD1	8151.0
USP19	8149.0
KLHL21	8147.0
NUP58	8140.0
SAE1	8125.0
H4C13	8117.0
DCAF6	8092.0
TTLL1	8078.0
NSMCE2	8071.0
SENP2	8056.0
H4C1	8017.0
FBXW11	8014.0
POFUT2	8009.0
GPIHBP1	7989.0
TMEM115	7987.0
ADAMTS8	7981.0
UBE2J2	7980.0
PSMB1	7978.0
PSMA6	7971.0
DNMT3A	7952.0
CAPZB	7951.0
TOMM20	7910.0
PTP4A2	7906.0
USP34	7897.0
RAB29	7890.0
SEC22B	7883.0
KLHL20	7870.0
UGGT1	7861.0
NUP98	7826.0
CYLD	7822.0
UBE2M	7791.0
ARFGAP2	7785.0
BLM	7764.0
DOLPP1	7751.0
FBXW4	7739.0
TRAF2	7733.0
COMMD4	7729.0
H2AC8	7728.0
TRAPPC6B	7722.0
RNF20	7716.0
GALNT11	7696.0
ZNF350	7693.0
DCTN4	7680.0
PSME2	7675.0
RAB6A	7657.0
DCTN6	7640.0
ACTR10	7623.0
DCAF8	7607.0
METTL21A	7580.0
PSMD1	7564.0
SEC22C	7549.0
H2BC4	7539.0
COPS8	7530.0
NFRKB	7529.0
RPS27A	7499.0
STX5	7498.0
GFUS	7497.0
FOLR2	7480.0
PSME1	7470.0
DPH2	7451.0
COP1	7448.0
RNF185	7436.0
PRKDC	7410.0
FEM1A	7389.0
COPZ1	7384.0
UBE2G1	7365.0
SPTB	7355.0
ATXN3	7354.0
NPL	7321.0
RAB35	7314.0
USP21	7266.0
RAB8B	7262.0
GCNT4	7247.0
DPM1	7239.0
THRA	7231.0
H2BC9	7228.5
BTBD1	7196.0
AMFR	7189.0
DCTN1	7179.0
TRIM4	7175.0
RAB30	7170.0
ETFB	7167.0
DAG1	7154.0
B4GALT6	7152.0
APC	7100.0
NANP	7093.0
COMMD10	7071.0
MBTPS1	7060.0
H4C8	7058.0
ARSK	7052.0
RAB5A	7043.0
HNRNPK	7040.0
PSMA3	7039.0
ASXL2	7034.0
RAB36	7013.0
JOSD2	7012.0
ACTR5	6978.0
PSMA1	6977.0
DPAGT1	6945.0
PSMD6	6942.0
PDIA6	6923.0
TNIP3	6910.0
H2AC17	6904.0
KTN1	6901.0
ARSG	6893.0
COPS5	6872.0
SPSB3	6868.0
PTRH2	6850.0
NUB1	6845.0
USP8	6839.0
ST3GAL5	6793.0
NR2C1	6783.0
SNX3	6782.0
MAT2B	6771.0
ATXN7	6733.0
TFG	6723.0
NUP37	6708.0
XPC	6707.0
H2AC21	6681.0
SUDS3	6677.0
PSMB3	6665.0
EIF5A2	6655.0
PHC2	6654.0
CUL7	6650.0
PSMD11	6649.0
DCAF11	6631.0
DHDDS	6599.0
PROZ	6598.0
PEX13	6574.0
RWDD3	6561.0
VGF	6546.0
MVD	6512.0
HSPA8	6500.0
SPTBN1	6494.0
TPR	6489.0
NEU1	6470.0
RNF139	6468.0
TMED3	6451.0
GGCX	6448.0
PSMD12	6422.0
ALPG	6410.0
HIPK2	6408.0
UHRF2	6378.0
TMEM129	6372.0
PSMB6	6370.0
GAN	6368.0
GOSR1	6364.0
ACTR1A	6363.0
H2BC8	6334.0
RAB12	6331.0
STAM2	6329.0
NUP160	6322.0
EDEM3	6319.0
GORASP1	6304.0
B3GNT2	6299.0
PSMD5	6295.0
PSME3	6289.0
CISH	6257.0
SIAH2	6239.0
COG7	6228.0
ASB13	6227.0
H2BC12	6220.0
ZRANB1	6203.0
RING1	6185.0
RPS2	6180.0
IL6	6166.0
MDM4	6157.0
TRAPPC5	6156.0
OTUD7B	6137.0
MYC	6135.0
GALNT10	6131.0
SOCS6	6129.0
EPAS1	6126.0
ZNF131	6121.0
DDB1	6110.0
CBX4	6103.0
DPH3	6064.0
HDAC1	6062.0
FBXW8	6055.0
ACTB	6053.0
RHOT1	6040.0
TOP2A	6036.0
RELA	6020.0
USP12	5987.0
PSMD9	5939.0
RAET1L	5925.0
WAC	5921.0
MAN1B1	5909.0
B3GALNT2	5903.0
PIGG	5896.0
POLB	5870.0
CUL4A	5867.0
UBE2B	5859.0
FBXO31	5838.0
UBE2H	5833.0
ALG1	5821.0
PPP6R1	5804.0
BST1	5801.0
TGFBR2	5792.0
SMAD2	5768.0
VASH1	5749.0
PLAUR	5747.0
SEH1L	5744.0
ASB6	5724.0
SVBP	5722.0
SIN3A	5710.0
SEC31A	5671.0
ST3GAL4	5650.0
DNAJC3	5642.0
USP13	5634.0
UCHL3	5608.0
RAB19	5603.0
FBXL19	5598.0
SUZ12	5592.0
ENGASE	5582.0
PRND	5552.0
LY6H	5551.0
H2AC16	5532.0
MGAT4B	5506.0
UBE2Q2	5502.0
MUC6	5482.0
NR1I2	5443.0
EDEM1	5411.0
ASB8	5407.0
PSMB2	5390.0
UBC	5385.0
NUP42	5371.0
RAB15	5369.0
MELTF	5345.0
NFKB2	5335.0
FGF23	5322.0
SEL1L	5320.0
BMI1	5313.0
TRAPPC9	5310.0
IGFBP3	5303.0
H4C3	5297.0
AURKA	5237.0
FEM1C	5211.0
CBX8	5208.0
GALNT2	5186.0
NUCB1	5163.0
PIGP	5136.0
DYNC1LI1	5132.0
MBD1	5130.0
ADAMTS7	5122.0
USP16	5104.0
MDM2	5073.0
PSMA7	5054.0
MGAT3	5041.0
INO80E	5030.0
DDX17	5027.0
TRAPPC6A	5006.0
DCUN1D4	4973.0
TTLL5	4964.0
TOP2B	4952.0
KBTBD6	4917.0
RXRA	4895.0
RANBP2	4890.0
ARCN1	4887.0
NAPG	4880.0
DCUN1D3	4871.0
CNIH1	4855.0
SEC13	4854.0
PARK7	4845.0
NUP214	4833.0
COPS7B	4815.0
CTSC	4814.0
SAR1B	4809.0
PHC3	4783.0
DHPS	4773.0
ST3GAL3	4765.0
RAB5B	4756.0
ALG6	4719.0
COPB2	4677.0
LARGE2	4671.0
LRRC41	4669.0
DDB2	4656.0
BCL10	4610.0
DCTN5	4586.0
APLP2	4539.0
PPP6R3	4532.0
SCMH1	4529.0
TRIM27	4525.0
SQSTM1	4520.0
WSB1	4494.0
NGLY1	4470.0
XRCC4	4468.0
UBE2T	4456.0
TRAPPC2L	4448.0
FBXW7	4447.0
B3GNTL1	4431.0
USP4	4428.0
INO80D	4422.0
FBXO9	4405.0
FBXO21	4404.0
DPP3	4384.0
ARF3	4380.0
PSMA8	4378.0
EEF1AKMT2	4345.0
CKAP4	4339.0
VDAC3	4338.0
CAND1	4321.0
SOCS2	4314.0
CANX	4306.0
SENP1	4304.0
FBXW2	4290.0
ARSA	4288.0
UBE2D3	4277.0
GATA3	4254.0
STX17	4251.0
TUBA4A	4239.0
RAB2A	4233.0
FBXO44	4218.0
ARF4	4207.0
NOTUM	4204.0
DYNLL1	4203.0
PPARGC1A	4184.0
MUC4	4165.0
KIN	4162.0
TPGS1	4158.0
CBX5	4150.0
MUC16	4128.0
SMC6	4127.0
ARSB	4123.0
TUBB2A	4122.0
HIC1	4109.0
POMGNT2	4097.0
INO80C	4091.0
H2AC13	4085.0
FBXO30	4084.0
PTEN	4078.0
PIGM	4065.0
PSMC2	4047.0
WRN	4033.0
TRIM13	4018.0
PIGF	4016.0
CUL1	4015.0
GBF1	4003.0
RNF168	4001.0
H4C2	3987.0
PSMB10	3971.0
CUL5	3961.0
DDOST	3936.0
MAN1C1	3933.0
TNIP1	3925.0
TUBB2B	3907.0
SMC5	3889.0
COPS4	3879.0
GALNT5	3865.0
FBXO11	3860.0
TTLL10	3836.0
TUBA4B	3811.0
PIGK	3807.0
SHPRH	3806.0
PHC1	3804.0
SPACA4	3802.0
SEC24D	3773.0
PAF1	3755.0
CNIH2	3746.0
COG5	3742.0
CP	3741.0
TRAPPC1	3735.0
SKP1	3705.0
FBXO22	3648.0
KDELR2	3617.0
H4C4	3596.0
RNF146	3594.0
PRSS21	3592.0
USP3	3574.0
L3MBTL2	3551.0
MYSM1	3540.0
BET1L	3531.0
F10	3522.0
RAB24	3516.0
TP53	3499.0
RAB38	3489.0
UBE2E1	3470.0
GMPPB	3469.0
USP47	3460.0
CD109	3416.0
SMAD3	3402.0
RAB10	3401.0
GMDS	3383.0
H2AC20	3382.0
STC2	3379.0
GOLGB1	3374.0
SLC17A5	3366.0
ST6GALNAC1	3363.0
PSMC3	3323.0
CCNF	3322.0
OS9	3293.0
NUP107	3276.0
AHSG	3273.0
PIGY	3262.0
SPTAN1	3255.0
NAGK	3190.0
BIRC2	3188.0
PSMC1	3148.0
PSME4	3137.0
DCTN2	3135.0
AGBL2	3102.0
CAPZA1	3088.0
MUC1	3086.0
WSB2	3085.0
NDC1	3079.0
PSMC5	3065.0
GALNT3	3051.0
PEX5	3036.0
TOPORS	3031.0
SEC24A	3029.0
DAD1	3027.0
TP53BP1	3014.0
FBXO32	3005.0
DERL2	3001.0
RHOA	3000.0
BET1	2998.0
NEDD8	2985.0
H2AC18	2954.5
H2AC19	2954.5
B3GNT4	2924.0
UBE2E3	2917.0
EDEM2	2890.0
COPG2	2885.0
FN1	2883.0
CUL3	2861.0
ELOC	2833.0
CBX2	2819.0
KCTD6	2802.0
H2AC7	2792.5
H2BC7	2792.5
BRCA1	2780.0
NCOA2	2754.0
HDAC7	2721.0
H2BC21	2718.0
TRAF3	2674.0
SPSB1	2650.0
MAP3K7	2632.0
MOGS	2631.0
PIGB	2622.0
ASXL1	2591.0
B3GLCT	2590.0
DPH1	2574.0
ALG10	2572.0
APOA5	2561.0
COPZ2	2539.0
PEX2	2504.0
NUP188	2493.0
ICMT	2468.0
PMM2	2458.0
CDKN1A	2387.0
NUP35	2378.0
KCTD7	2358.0
TOP1	2345.0
TUBB4B	2340.0
SUMF2	2323.0
USP15	2312.0
PSMB8	2300.0
GALNT1	2285.0
USP28	2260.0
GALNT7	2258.0
USP30	2233.0
USP2	2228.0
TTLL4	2216.0
ARFGAP3	2160.0
RNF5	2156.0
FBXL16	2155.0
SPTA1	2136.0
NAPB	2126.0
POMT2	2125.0
COMMD1	2104.0
H2BC5	2100.0
RRAGA	2063.0
NSMCE1	2058.0
SP100	2046.0
FBXO6	2038.0
POM121C	2036.0
ADAM10	2017.0
ALG8	2010.0
TOMM70	2006.0
RAB18	2005.0
LGALS1	1973.0
ANKRD9	1955.0
MANEA	1946.0
RAB14	1930.0
PSMD14	1903.0
COG4	1895.0
UBE2S	1865.0
H2BC17	1857.0
ESR1	1837.0
H2BC13	1834.0
ARF1	1827.0
DDX5	1755.0
POMT1	1753.0
KLHL2	1748.0
CLSPN	1743.0
RAB1A	1737.0
PGM3	1733.0
PSMB11	1723.0
KEAP1	1708.0
RAB27B	1685.0
SPTBN2	1662.0
NEU4	1653.0
CST3	1643.0
MBD5	1639.0
TNKS	1634.0
CALR	1632.0
ALG14	1609.0
ST8SIA4	1603.0
AREG	1585.0
SERPIND1	1578.0
UBE2D2	1556.0
INO80B	1555.0
KLHL3	1554.0
COPS7A	1551.0
ARSJ	1548.0
KLHL25	1524.0
FUT8	1510.0
MIA2	1491.0
PIGQ	1475.0
AGBL3	1463.0
RNF152	1445.0
IDE	1444.0
RAB3D	1415.0
NEURL2	1398.0
DPM2	1391.0
SOCS5	1390.0
B4GALT2	1375.0
CDK1	1360.0
H2AC25	1333.0
USP48	1328.0
TPGS2	1296.0
SCG2	1292.0
H2BC11	1286.0
TFPT	1282.0
NCOA1	1280.0
ADAMTS6	1256.0
COG8	1233.0
MPI	1181.0
KBTBD8	1150.0
PALB2	1148.0
GPLD1	1136.0
FUCA1	1131.0
CDC25A	1124.0
UCHL5	1122.0
NR1H3	1117.0
ZBTB16	1109.0
ADAMTS10	1104.0
SLC35A1	1058.0
VCPIP1	1055.0
ARRB1	1053.0
RAB11A	1050.0
TBC1D20	1039.0
TUBA1A	1018.0
TNFAIP3	1016.0
ADAMTSL4	1014.0
ARF5	944.0
NSMCE3	938.0
VCP	920.0
NFE2L2	886.0
USP37	840.0
AGBL5	834.0
AURKB	823.0
ING2	816.0
EIF5A	804.0
SMAD1	803.0
PIGU	777.0
SUMO2	766.0
RAB43	757.0
STAM	744.0
RAET1G	740.0
GALNT16	736.0
CCP110	730.0
WDR48	701.0
PIAS2	681.0
NOP58	680.0
CAPZA2	668.0
RAB1B	655.0
USP24	640.0
NLRP3	615.0
CDC20	611.0
TGFA	600.0
STAMBP	580.0
PCNA	570.0
NUP43	561.0
HSP90B1	545.0
NEU3	527.0
NAE1	505.0
TULP4	480.0
TMED7	460.0
NOD1	457.0
KLHL5	426.0
PEX12	374.0
ASB17	371.0
TTLL3	365.0
NUP205	331.0
PUM2	327.0
TMED9	318.0
TF	313.0
COMMD2	310.0
FBXW5	304.0
ANK1	268.0
UBXN7	254.0
ADRB2	250.0
HRC	240.0
CDKN2A	229.0
ADAMTSL5	221.0
MEN1	220.0
BECN1	214.0
TRAF6	213.0
APP	210.0
UBD	205.0
PIGZ	197.0
COG3	179.0
GFPT1	169.0
UBE2W	159.0
TUBB6	150.0
ALPL	148.0
PGAP1	141.0
GALNT4	138.0
USO1	135.0
DCAF5	129.0
USP33	120.0
MAN1A2	107.0
USP10	79.0
APOE	71.0
GALNTL5	55.0
RAD23A	46.0
POMGNT1	30.0
MIA3	25.0
MUC5B	-1.0
NR5A1	-18.0
RAB20	-43.0
SEC16B	-47.0
USP14	-57.0
RNF7	-73.0
ST8SIA6	-111.0
RAB4A	-161.0
BABAM2	-162.0
ANK3	-265.0
H4C9	-276.0
COMMD3	-279.0
LTBP1	-291.0
B4GALT1	-301.0
MDGA1	-320.0
DCAF13	-321.0
SENP8	-323.0
APOA1	-340.0
RAB2B	-351.0
TUBB4A	-357.0
TUBA8	-372.0
DPH5	-389.0
UBE2G2	-401.0
RAB31	-484.0
DCAF10	-507.0
RAD23B	-510.0
ADAMTS13	-533.0
OTUB1	-534.0
PIGV	-546.0
DCAF16	-562.0
LY6E	-563.0
FKBP8	-577.0
VDR	-578.0
MUC20	-619.0
NTNG1	-623.0
RAB34	-638.0
ALB	-650.0
VHL	-675.0
KLHL9	-718.0
UCHL1	-774.0
NSMCE4A	-805.0
SEC23A	-814.0
NRN1	-842.0
FAM20C	-854.0
VDAC2	-858.0
SRD5A3	-859.0
SKP2	-864.0
RTN4RL2	-882.0
CAMKMT	-888.0
PRSS41	-893.0
THBS2	-944.0
ALPI	-977.0
GNPNAT1	-985.0
MCFD2	-997.0
SPSB4	-1013.0
TTLL8	-1017.0
B3GNT9	-1039.0
PENK	-1044.0
DPM3	-1068.0
EEF2KMT	-1070.0
FBXL5	-1073.0
LMAN2L	-1131.0
DNMT1	-1138.0
TRIM28	-1179.0
CUL2	-1184.0
DCAF17	-1226.0
TECTA	-1240.0
LMAN1	-1248.0
VCAN	-1266.0
PIGH	-1273.0
CTR9	-1278.0
MFGE8	-1281.0
PIAS1	-1320.0
GALNT9	-1334.0
CHST10	-1345.0
B4GALNT2	-1347.0
FBXO27	-1351.0
CGA	-1355.0
UBA6	-1362.0
ST8SIA1	-1376.0
EEF1A1	-1425.0
UBE2D1	-1471.0
MDC1	-1484.0
TMED2	-1538.0
TRIM25	-1558.0
SPTBN4	-1563.0
FBXL20	-1584.0
MARCHF6	-1586.0
CHGB	-1589.0
ST8SIA5	-1598.0
RAB27A	-1620.0
MATN3	-1662.0
PRMT3	-1663.0
RAB40B	-1664.0
MXRA8	-1665.0
COG6	-1671.0
TGOLN2	-1672.0
ENAM	-1679.0
NUDT14	-1697.0
OBSL1	-1704.0
USP25	-1706.0
ALG10B	-1747.0
FBXL13	-1785.0
ADAMTS20	-1845.0
RBBP5	-1889.0
FBXO17	-1911.0
NANS	-1924.0
SHISA5	-1956.0
LAMC1	-1993.0
COPB1	-2012.0
FBXL15	-2061.0
FPGT	-2064.0
TFAP2C	-2068.0
RARA	-2083.0
MUC5AC	-2110.0
FOXL2	-2143.0
B3GNT3	-2146.0
SPTBN5	-2148.0
NSF	-2180.0
COPS3	-2205.0
SCFD1	-2211.0
FBXO41	-2224.0
RBX1	-2227.0
UBA52	-2237.0
DOLK	-2289.0
IFIH1	-2291.0
NPM1	-2297.0
RAB3A	-2300.0
NFKBIA	-2315.0
CNIH3	-2326.0
UBB	-2335.0
RNF2	-2391.0
BIRC3	-2406.0
MUC7	-2427.0
ETFBKMT	-2470.0
GALNT8	-2496.0
FGA	-2515.0
TTLL7	-2534.0
LEO1	-2535.0
NUP153	-2541.0
MUC3A	-2569.0
ABRAXAS1	-2572.0
ASB14	-2586.0
MGAT2	-2643.5
RAB6B	-2649.0
SMAD4	-2666.0
UBA3	-2699.0
RAB37	-2712.0
TFAP2A	-2715.0
LRRC49	-2730.0
MAN1A1	-2748.0
DNAJC24	-2749.0
SP3	-2753.0
TTLL9	-2763.0
RORA	-2774.0
DYNC1I2	-2797.0
SBSPON	-2836.0
SEMA5B	-2844.0
NR3C1	-2846.0
GALNT13	-2857.0
CMAS	-2864.0
TRAPPC4	-2867.0
H2BC26	-2895.0
OTOA	-2935.0
RIGI	-2937.0
PSMB9	-2938.0
NEGR1	-2972.0
ASGR1	-2977.0
YOD1	-2986.0
RAB4B	-2999.0
SLC35C1	-3001.0
ULBP2	-3042.0
COMMD7	-3056.0
ASB4	-3092.0
FBXO15	-3152.0
AXIN2	-3173.0
RAB33B	-3195.0
BARD1	-3201.0
NUP155	-3213.0
SERPINC1	-3248.0
NR5A2	-3280.0
PIGX	-3295.0
CPM	-3309.0
RAD21	-3318.0
ADAMTSL2	-3330.0
IGFBP7	-3353.0
RAB22A	-3363.0
DNMT3B	-3433.0
PEX10	-3447.0
NEU2	-3506.0
VDAC1	-3516.0
SUMO1	-3539.0
TUBA3D	-3545.0
TUBA1C	-3556.0
SDC2	-3558.0
CCDC8	-3581.0
GALNT14	-3582.0
NR3C2	-3588.0
FEM1B	-3589.0
FBXO2	-3703.0
TRAPPC3	-3723.0
ERCC8	-3759.0
FSTL3	-3796.0
ARSI	-3801.0
NOD2	-3808.0
CEACAM5	-3818.0
UBE2K	-3824.0
AFP	-3826.0
UBE2C	-3845.0
STAMBPL1	-3851.0
SPON2	-3853.0
ASB15	-3864.0
ST6GALNAC6	-3869.0
NTM	-3891.0
BAP1	-3896.0
KNG1	-3949.0
ADAMTSL1	-3967.0
CDC34	-3973.0
ASB10	-3981.0
LY6G6C	-3988.0
TUBB3	-4002.0
ASB18	-4004.0
DMP1	-4017.0
THSD4	-4024.0
LYPD5	-4043.0
CCNA1	-4120.0
NR1H4	-4138.0
RUVBL1	-4145.0
LRR1	-4192.0
RAB32	-4269.0
H2AC1	-4272.0
CNTN5	-4293.0
FUCA2	-4295.0
PIGT	-4301.0
TNC	-4315.0
GALNT17	-4317.0
PSMA5	-4331.0
ST6GALNAC5	-4354.0
PROS1	-4391.0
LYPD3	-4422.0
RAB13	-4435.0
COG2	-4446.0
H2BC1	-4453.0
BTBD6	-4460.0
DCUN1D5	-4498.0
UBE2Z	-4518.0
PRKN	-4525.0
DPH6	-4538.0
BIRC5	-4539.0
HIF1A	-4580.0
RTN4RL1	-4602.0
GALNT18	-4621.0
OTUB2	-4629.0
MITF	-4640.0
ADAMTS1	-4642.0
VNN2	-4649.0
TNIP2	-4650.0
TUBA3E	-4662.0
COL7A1	-4672.0
GFPT2	-4689.0
NR4A2	-4692.0
TNKS2	-4742.0
HLA-A	-4744.0
ADAMTS19	-4809.0
TFAP2B	-4812.0
TTLL6	-4830.0
ADAMTS17	-4841.0
LY6K	-4842.0
ANK2	-4910.0
BMP4	-4930.0
LYPD1	-4972.0
SEMA5A	-5002.0
C3	-5027.0
LMO7	-5044.0
PSMD8	-5050.0
UGGT2	-5073.0
EID3	-5079.0
SCG3	-5092.0
IGFBP4	-5134.0
FBN1	-5138.0
ADAMTSL3	-5143.0
OPCML	-5199.0
FUOM	-5216.0
MDGA2	-5229.0
ST6GAL2	-5232.0
GOSR2	-5270.0
PLET1	-5277.0
MUC13	-5329.0
DYNC1I1	-5334.0
TTLL11	-5345.0
VWA1	-5405.0
H2AC14	-5418.0
AMBN	-5429.0
ADAMTS5	-5452.0
KLHL11	-5456.0
TTLL2	-5514.0
WFS1	-5554.0
UMOD	-5563.0
FBXL4	-5609.0
ADAMTS2	-5635.0
USP49	-5664.0
PSCA	-5675.0
GPAA1	-5679.0
TAF10	-5681.0
RAB26	-5690.0
SPON1	-5693.0
USP44	-5721.0
FBXO40	-5727.0
H2BC3	-5733.0
ADAMTS18	-5739.0
SPSB2	-5761.0
PIAS3	-5823.0
TPST1	-5828.0
SPARCL1	-5847.0
PRSS23	-5863.0
H4C16	-5871.0
CCNA2	-5945.0
GALNTL6	-5964.0
ST6GALNAC3	-5968.0
IGFBP5	-5986.0
FBXL8	-6004.0
GRIA1	-6007.0
F7	-6008.0
THBS1	-6013.0
F5	-6033.0
PIGW	-6041.0
LYPD6B	-6105.0
MUC17	-6112.0
PCGF2	-6146.0
ADAMTS3	-6163.0
AGBL4	-6187.0
OTUD7A	-6203.0
LARGE1	-6282.0
CHST8	-6302.0
THSD7B	-6329.0
ADAMTS9	-6330.0
TUBA1B	-6340.0
INS	-6353.0
LAMB1	-6380.0
SERPINA10	-6390.0
RAB3B	-6391.0
VNN1	-6404.0
ASB2	-6415.0
FAM20A	-6427.0
THSD7A	-6454.0
MEPE	-6456.0
ASGR2	-6472.0
TUSC3	-6483.0
ADAMTS12	-6507.0
TUBB1	-6519.0
PCSK9	-6520.0
A4GNT	-6535.0
CDH2	-6551.0
GPS1	-6560.0
AGTPBP1	-6591.0
RAB3C	-6604.0
FGG	-6723.0
ADAMTS14	-6739.0
RAB17	-6768.0
MUC21	-6781.0
PGR	-6783.0
RECK	-6803.0
ST8SIA3	-6814.0
UBE2N	-6864.0
LMAN1L	-6902.0
KDELR1	-6907.0
SSPOP	-6939.0
RAB39A	-6941.0
SATB2	-6943.0
ST3GAL6	-6994.0
H2BC14	-7035.0
AGBL1	-7062.0
FOLR1	-7106.0
NTNG2	-7147.0
CNTN4	-7148.0
H4C12	-7199.0
SERPINA1	-7239.0
CHST4	-7257.0
TUBA3C	-7269.0
HIF3A	-7272.0
TUBAL3	-7278.0
NRIP1	-7332.0
RABGGTB	-7411.0
HDAC2	-7451.0
FSTL1	-7460.0
SEM1	-7461.0
ADAMTS16	-7470.0
LSAMP	-7508.0
ASB16	-7542.0
TTLL13	-7610.0
THRB	-7619.0
PPARG	-7622.0
TECTB	-7625.0
B4GALT5	-7628.0
FN3K	-7684.0
LYPD2	-7703.0
AMTN	-7710.0
MSLN	-7739.0
PIGC	-7757.0
FBXL7	-7868.0
MGAT4C	-7910.0
ANKRD28	-7958.0
MUC12	-8069.0
THSD1	-8080.0
MUCL1	-8091.0
SPP2	-8093.0
EVA1A	-8094.0
FBXL12	-8149.0
SOCS3	-8205.0
BGLAP	-8235.0
APOB	-8243.0
TMEM132A	-8259.0
NICN1	-8304.0
ASB5	-8319.0
ADAMTS15	-8323.0
CFTR	-8343.0
IZUMO1R	-8386.0
KLHL41	-8410.0
ART4	-8414.0
MUC15	-8427.0
CNTN3	-8457.0
ST8SIA2	-8497.0
B3GNT6	-8516.0
GP2	-8519.0
LY6D	-8545.0
B3GNT7	-8547.0
RAB42	-8682.0
CCN1	-8768.0
GALNT15	-8788.0
APOL1	-8795.0
ITIH2	-8827.0
CAPZA3	-8836.0
CEACAM7	-8924.0
FCGR3B	-8938.0
TUBB8	-8942.0
IKBKE	-8971.0
SPP1	-8995.0
THY1	-9019.0
IL33	-9101.0
LYPD8	-9337.0
IGFBP1	-9400.0
SPRN	-9692.0

---

REACTOME_HIV_INFECTION

REACTOME_HIV_INFECTION

	175
set	REACTOME_HIV_INFECTION
setSize	223
pANOVA	9.07e-18
s.dist	0.333
p.adjustANOVA	1.24e-15

Top enriched genes

Top 20 genes

GeneID	Gene Rank
LCK	11904
POLR2J	11816
SUPT5H	11758
CD28	11682
AP2M1	11598
RANGAP1	11517
POLR2A	11407
POLR2E	11395
AP2A2	11289
PSMB4	11076
PSMD4	10893
RAE1	10890
PSMD13	10870
ERCC3	10866
CHMP4B	10836
PSMA2	10707
GTF2A1	10680
AP1B1	10665
ELOB	10535
NUP210	10455

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
LCK	11904
POLR2J	11816
SUPT5H	11758
CD28	11682
AP2M1	11598
RANGAP1	11517
POLR2A	11407
POLR2E	11395
AP2A2	11289
PSMB4	11076
PSMD4	10893
RAE1	10890
PSMD13	10870
ERCC3	10866
CHMP4B	10836
PSMA2	10707
GTF2A1	10680
AP1B1	10665
ELOB	10535
NUP210	10455
PSMC6	10418
POLR2B	10306
PAK2	10228
NUP62	10167
TAF4	10162
NELFCD	10110
NUP85	10023
PSMD3	9979
NUP54	9855
TAF13	9847
PSMD7	9804
CD247	9759
NELFB	9731
PSMC4	9692
AP1M2	9672
PSMD2	9598
NUP88	9522
PPIA	9515
PSMB5	9461
RAC1	9456
NUP133	9347
BTRC	9324
VPS37C	9072
VPS37B	9063
PSMF1	9002
FURIN	8913
CHMP2A	8906
XPO1	8891
BANF1	8827
TCEA1	8796
NELFE	8758
APOBEC3G	8739
CCNT1	8657
NELFA	8636
GTF2F1	8571
PSMB7	8555
LIG1	8548
NUP93	8494
PSMA4	8487
CCNK	8473
CCNH	8458
POLR2H	8450
VPS4B	8449
CHMP2B	8258
POM121	8233
NUP50	8160
AAAS	8159
NUP58	8140
CHMP4A	8022
PSMB1	7978
PSMA6	7971
VPS28	7949
TAF3	7849
NUP98	7826
AP2S1	7803
MVB12B	7759
TAF2	7715
PSME2	7675
TSG101	7622
PSMD1	7564
RPS27A	7499
PSME1	7470
TAF4B	7454
GTF2E1	7447
ELL	7361
NCBP2	7200
PSMA3	7039
PSMA1	6977
PSMD6	6942
NUP37	6708
PSMB3	6665
PSMD11	6649
FEN1	6610
SUPT16H	6552
RNGTT	6547
TPR	6489
PSMD12	6422
TAF1L	6402
PSMB6	6370
NUP160	6322
PSMD5	6295
PSME3	6289
XRCC5	6243
CDK7	6114
PSMD9	5939
SLC25A4	5865
VPS37D	5847
AP1M1	5820
VPS4A	5772
PACS1	5766
SEH1L	5744
AP2A1	5736
TBP	5601
GTF2H3	5566
ELOA	5436
PSMB2	5390
UBC	5385
NUP42	5371
VPS37A	5285
POLR2I	5214
ERCC2	5135
CHMP7	5074
RAN	5055
PSMA7	5054
POLR2G	4982
RANBP2	4890
SEC13	4854
RCC1	4850
GTF2H1	4840
NUP214	4833
PDCD6IP	4812
TAF7	4746
DOCK2	4642
POLR2F	4630
XRCC4	4468
UBAP1	4463
PSMA8	4378
CHMP6	4359
AP2B1	4341
PSMC2	4047
ELMO1	4026
TAF15	4012
PSMB10	3971
CUL5	3961
CHMP3	3762
GTF2H5	3727
SKP1	3705
CD8B	3697
CXCR4	3682
RNMT	3418
PSMC3	3323
NUP107	3276
AP1S3	3259
POLR2D	3258
PSMC1	3148
PSME4	3137
NDC1	3079
PSMC5	3065
ATP6V1H	3050
ELOC	2833
GTF2B	2820
GTF2E2	2708
NUP188	2493
NMT1	2410
VTA1	2396
NUP35	2378
PSMB8	2300
CTDP1	2201
GTF2H4	2092
POM121C	2036
TAF6	1945
PSMD14	1903
TAF12	1849
ARF1	1827
TAF5	1730
PSMB11	1723
GTF2A2	1343
AP1S1	908
XRCC6	839
LIG4	829
HCK	797
NUP43	561
MVB12A	451
NUP205	331
FYN	61
KPNB1	32
NCBP1	-175
TAF9	-183
NEDD4L	-256
MNAT1	-336
SSRP1	-796
NMT2	-806
KPNA1	-925
TAF11	-999
AP1G1	-1050
GTF2F2	-1392
POLR2L	-1678
CDK9	-1861
RANBP1	-1938
PSIP1	-1996
RBX1	-2227
UBA52	-2237
NPM1	-2297
UBB	-2335
NUP153	-2541
CHMP5	-2668
PSMB9	-2938
NUP155	-3213
POLR2K	-3852
CD4	-4035
CCNT2	-4325
PSMA5	-4331
HLA-A	-4744
PSMD8	-5050
TAF10	-5681
POLR2C	-6018
SUPT4H1	-6345
CHMP4C	-6820
ELOA2	-7031
B2M	-7174
SEM1	-7461
HMGA1	-7614
CCR5	-9073

---

REACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53

REACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53

	591
set	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53
setSize	351
pANOVA	1.09e-17
s.dist	0.266
p.adjustANOVA	1.38e-15

Top enriched genes

Top 20 genes

GeneID	Gene Rank
BRD1	12058
PDPK1	11829
POLR2J	11816
LAMTOR3	11769
SUPT5H	11758
CREBBP	11715
BRPF1	11679
TFDP1	11506
POLR2A	11407
POLR2E	11395
AGO1	11345
RNF34	11329
GATAD2A	11072
MTOR	11011
BANP	11002
PPP2R1B	10998
USP7	10931
CHD3	10888
ERCC3	10866
RAD9A	10850

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
BRD1	12058
PDPK1	11829
POLR2J	11816
LAMTOR3	11769
SUPT5H	11758
CREBBP	11715
BRPF1	11679
TFDP1	11506
POLR2A	11407
POLR2E	11395
AGO1	11345
RNF34	11329
GATAD2A	11072
MTOR	11011
BANP	11002
PPP2R1B	10998
USP7	10931
CHD3	10888
ERCC3	10866
RAD9A	10850
PIP4P1	10816
DAXX	10716
PMS2	10704
YWHAE	10677
RPA1	10676
GPX2	10608
PRR5	10543
ELOB	10535
COX16	10473
PIP4K2A	10408
POLR2B	10306
E2F4	10203
TAF4	10162
NELFCD	10110
RMI2	10057
COX6B1	10052
CHD4	10037
TACO1	10013
CNOT3	9998
CDC25C	9899
BID	9888
RMI1	9852
TAF13	9847
TNFRSF10D	9810
AKT1	9802
COX14	9790
CDK5R1	9783
COX8A	9775
PRKAB1	9761
GADD45A	9743
NELFB	9731
AGO2	9717
PLK3	9710
RPTOR	9678
ARID3A	9655
LAMTOR1	9581
CDK13	9570
YWHAG	9563
CENPJ	9539
E2F8	9534
CNOT1	9481
TNFRSF10B	9467
RFFL	9452
RABGGTA	9443
FANCI	9428
SMYD2	9416
TNRC6C	9415
CASP2	9410
EP300	9390
CDKN1B	9381
NDUFA4	9254
ZNF420	9246
KMT5A	9179
APAF1	9150
CDK12	9144
DDIT4	9141
STK11	9027
LAMTOR4	8940
PHF20	8925
PRMT5	8850
TCEA1	8796
KAT6A	8784
NELFE	8758
TFDP2	8744
MAP2K6	8671
CCNT1	8657
CNOT11	8644
NELFA	8636
COX19	8609
CASP10	8604
GTF2F1	8571
CCNK	8473
CCNH	8458
POLR2H	8450
RFC2	8432
AKT2	8422
RBL2	8353
CARM1	8334
EHMT1	8321
PIDD1	8298
CASP6	8250
PML	8234
PLAGL1	8171
CNOT4	8107
TOPBP1	8095
GLS	7990
DNA2	7894
TAF3	7849
GSR	7831
RHEB	7765
BLM	7764
CSNK2A1	7758
PIN1	7723
TAF2	7715
PRKAB2	7695
NOC2L	7694
TNRC6A	7634
MBD3	7608
CDK5	7545
RPS27A	7499
TAF4B	7454
FANCD2	7450
RBBP8	7402
ELL	7361
EHMT2	7223
GPI	7195
NDRG1	7185
PRELID3A	7149
COX5A	7138
TMEM219	6938
SUPT16H	6552
MLH1	6506
ZNF385A	6469
CNOT6	6456
MSH2	6423
DYRK2	6420
HIPK2	6408
TAF1L	6402
TSC2	6400
COX6C	6367
TP53INP1	6350
SURF1	6325
PIP4K2B	6253
MAPKAP1	6204
MDM4	6157
TNRC6B	6144
JMY	6120
CDK7	6114
HDAC1	6062
YWHAQ	5997
RBL1	5966
CSNK2A2	5953
PRKAA1	5866
MEAF6	5790
TIGAR	5684
JUN	5629
TBP	5601
PRDX5	5581
GTF2H3	5566
CSNK2B	5559
TOP3A	5504
ELOA	5436
UBC	5385
CNOT8	5346
PRKAG2	5343
IGFBP3	5303
AURKA	5237
POLR2I	5214
RPA2	5194
MAPK14	5180
ERCC2	5135
MDM2	5073
RFC5	5072
PPP2R5C	5016
KAT5	5000
POLR2G	4982
CHEK1	4981
GTF2H1	4840
CNOT7	4797
TSC1	4794
TAF7	4746
DDB2	4656
POLR2F	4630
RFC4	4504
AIFM2	4373
PPP2R1A	4310
TNFRSF10A	4205
POU4F1	4082
PTEN	4078
BRPF3	4071
CYCS	4068
WRN	4033
TAF15	4012
GATAD2B	3962
RBBP4	3878
YWHAH	3875
BRIP1	3816
GTF2H5	3727
CNOT6L	3685
HIPK1	3677
MRE11	3571
MAPKAPK5	3566
TP53	3499
RAD51D	3495
TNKS1BP1	3488
MTA2	3431
AGO3	3420
PRMT1	3343
PMAIP1	3340
POLR2D	3258
BRD7	3149
RPA3	3146
COX7A2L	3104
BCL6	3059
COX4I1	3049
LRPPRC	3047
ELOC	2833
BRCA1	2780
RFC3	2692
TTC5	2683
PRKAG1	2584
COX11	2459
SGK1	2406
CDKN1A	2387
COX6A1	2351
USP2	2228
PRDX1	2226
CTDP1	2201
ATR	2151
RAD9B	2147
ATM	2137
CCNB1	2131
GTF2H4	2092
PCBP4	2069
RRAGA	2063
TXN	2053
TXNRD1	2049
TP53AIP1	2047
ING5	2015
COX5B	1997
E2F7	1968
BTG2	1962
TAF6	1945
CHEK2	1906
TAF12	1849
SESN1	1738
TAF5	1730
GLS2	1688
PRDM1	1581
PPP1R13B	1543
CDK1	1360
CNOT10	1347
CNOT9	1258
RICTOR	1224
STEAP3	1196
YWHAZ	1179
MOV10	1158
RAD1	1126
CNOT2	924
PIP4K2C	856
MLST8	854
AURKB	823
ING2	816
TPX2	786
PCNA	570
AKT3	516
FANCC	498
PPP2CB	497
ATRIP	448
CDKN2A	229
YWHAB	170
COX7C	-37
TAF9	-183
MNAT1	-336
TP53RK	-391
RRAGD	-414
L3MBTL1	-677
NBN	-689
SSRP1	-796
TAF11	-999
SCO1	-1148
FOS	-1163
CRADD	-1171
RRM2B	-1174
RAD50	-1348
GTF2F2	-1392
PRELID1	-1452
PRDX2	-1476
MDC1	-1484
TNFRSF10C	-1520
PPP1R13L	-1666
POLR2L	-1678
CDK9	-1861
RHNO1	-1864
POU4F2	-1871
RGCC	-1968
BNIP3L	-2005
RRAGC	-2062
PPP2CA	-2084
FAS	-2215
UBA52	-2237
PERP	-2247
SETD9	-2288
NPM1	-2297
CDK2	-2309
UBB	-2335
TP73	-2448
NUAK1	-2855
CCNE1	-2947
EXO1	-3131
SESN2	-3193
BARD1	-3201
CCNG1	-3203
COX18	-3348
CCNE2	-3373
LAMTOR5	-3417
SLC38A9	-3577
RAD17	-3609
ATF2	-3617
NLRC4	-3619
MAPK11	-3828
POLR2K	-3852
COX20	-3906
CCNA1	-4120
PLK2	-4300
CCNT2	-4325
SESN3	-4443
TRIAP1	-4479
BIRC5	-4539
SCO2	-4677
BBC3	-4813
PRKAA2	-4922
AGO4	-5113
TAF10	-5681
PRKAG3	-5700
CCNA2	-5945
HUS1	-5999
POLR2C	-6018
TP63	-6137
BCL2L14	-6235
SUPT4H1	-6345
TP53BP2	-6425
TP53I3	-6772
ELOA2	-7031
LAMTOR2	-7256
RABGGTB	-7411
HDAC2	-7451
CASP1	-7866
BAX	-8183
E2F1	-8231
SFN	-8574

---

REACTOME_CHROMATIN_MODIFYING_ENZYMES

REACTOME_CHROMATIN_MODIFYING_ENZYMES

	558
set	REACTOME_CHROMATIN_MODIFYING_ENZYMES
setSize	252
pANOVA	2.85e-17
s.dist	0.309
p.adjustANOVA	3.35e-15

Top enriched genes

Top 20 genes

GeneID	Gene Rank
BRD1	12058
CREBBP	11715
TADA2B	11706
BRPF1	11679
COPRS	11634
YEATS2	11543
H2BC15	11524
KMT2D	11499
SMARCA4	11496
H4C5	11447
DOT1L	11443
SMARCB1	11429
H2BC6	11322
USP22	11278
SMARCC2	11212
KMT2B	11211
MTA1	11188
GATAD2A	11072
NCOR2	11049
ATXN7L3	11009

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
BRD1	12058.0
CREBBP	11715.0
TADA2B	11706.0
BRPF1	11679.0
COPRS	11634.0
YEATS2	11543.0
H2BC15	11524.0
KMT2D	11499.0
SMARCA4	11496.0
H4C5	11447.0
DOT1L	11443.0
SMARCB1	11429.0
H2BC6	11322.0
USP22	11278.0
SMARCC2	11212.0
KMT2B	11211.0
MTA1	11188.0
GATAD2A	11072.0
NCOR2	11049.0
ATXN7L3	11009.0
CHD3	10888.0
H2AZ1	10867.0
SETD1A	10831.0
KDM1B	10773.0
SUPT7L	10771.0
SAP30L	10745.0
KDM4B	10657.0
ARID1A	10632.0
H2AC15	10614.0
NSD2	10532.0
SGF29	10387.0
EPC1	10250.0
NCOR1	10213.0
ELP3	10211.0
MCRS1	10068.0
CHD4	10037.0
SETD1B	10015.0
KMT2C	9984.0
H2AC12	9830.0
TADA1	9720.0
KANSL3	9638.0
ELP2	9590.0
WDR5	9587.0
H2AC4	9477.0
PRMT7	9429.0
SMYD2	9416.0
EP300	9390.0
DMAP1	9370.0
JADE1	9302.0
KAT2B	9295.0
TRRAP	9187.0
KMT5A	9179.0
KMT5C	9171.0
WDR77	9157.0
EP400	9151.0
TADA3	9149.0
SAP130	9133.0
PHF2	9113.0
H4C6	9077.0
KDM2B	8979.0
PHF20	8925.0
H3C11	8908.0
H2BC10	8901.0
KANSL1	8856.0
PRMT5	8850.0
KMT2A	8841.0
ING3	8816.0
KAT6A	8784.0
H2AC11	8737.0
ARID1B	8673.0
RCOR1	8525.0
KAT2A	8511.0
HAT1	8471.0
NSD3	8387.0
ACTL6A	8382.0
CARM1	8334.0
EHMT1	8321.0
H2AC6	8277.0
H4C11	8241.0
ING4	8200.0
H4C13	8117.0
KDM5A	8112.0
SMARCC1	8102.0
KDM1A	8061.0
H4C1	8017.0
DNMT3A	7952.0
KDM2A	7896.0
H2AC8	7728.0
JMJD6	7610.0
MBD3	7608.0
ARID4A	7579.0
H2BC4	7539.0
H3C1	7395.0
MTA3	7374.0
SETD2	7345.0
KMT2E	7299.0
SAP30	7289.0
H2BC9	7228.5
H3C7	7228.5
EHMT2	7223.0
H4C8	7058.0
SMARCD2	6948.0
H2AC17	6904.0
KDM4C	6867.0
KAT6B	6861.0
KANSL2	6858.0
GPS2	6767.0
ATXN7	6733.0
SAP18	6685.0
H2AC21	6681.0
SUDS3	6677.0
H3C10	6652.0
CLOCK	6442.0
H2BC8	6334.0
SETDB1	6221.0
H2BC12	6220.0
RPS2	6180.0
HDAC1	6062.0
RIOX2	6058.0
JAK2	6056.0
ACTB	6053.0
RELA	6020.0
SMARCA2	5954.0
H3C4	5911.0
TAF6L	5881.0
BRD8	5815.0
MEAF6	5790.0
MSL1	5775.0
MBIP	5641.0
SUZ12	5592.0
ENY2	5568.0
H2AC16	5532.0
PBRM1	5510.0
KAT7	5499.0
HDAC3	5406.0
RUVBL2	5400.0
NFKB2	5335.0
H4C3	5297.0
NSD1	5170.0
H2AJ	5141.0
KAT5	5000.0
ELP6	4905.0
JADE2	4889.0
KDM4A	4813.0
MRGBP	4760.0
KDM7A	4502.0
KDM6B	4437.0
KDM4D	4393.0
MORF4L1	4333.0
H2AC13	4085.0
BRPF3	4071.0
KDM3B	4046.0
H4C2	3987.0
GATAD2B	3962.0
RBBP4	3878.0
SETD3	3718.0
HDAC10	3671.0
H4C4	3596.0
AEBP2	3547.0
H3C8	3521.0
MTA2	3431.0
TAF5L	3386.0
H2AC20	3382.0
PRMT1	3343.0
TADA2A	3257.0
ASH1L	3101.0
SMYD3	2983.0
H2AC18	2954.5
H2AC19	2954.5
ZZZ3	2898.0
SMARCD1	2809.0
H2AC7	2792.5
H2BC7	2792.5
NCOA2	2754.0
H2BC21	2718.0
SUPT20H	2564.0
ARID4B	2538.0
ELP5	2317.0
CDK4	2268.0
H2BC5	2100.0
ING5	2015.0
KDM5B	2000.0
H2BC17	1857.0
TAF12	1849.0
H2BC13	1834.0
H3C2	1828.0
ELP4	1806.0
MSL2	1591.0
ARID2	1517.0
ATF7IP	1450.0
DR1	1339.0
H2AC25	1333.0
H2BC11	1286.0
NCOA1	1280.0
KAT8	1130.0
EED	774.0
BRWD1	391.0
SETD7	339.0
TBL1XR1	245.0
DPY30	230.0
YEATS4	145.0
KDM3A	28.0
TAF9	-183.0
H4C9	-276.0
VPS72	-342.0
PAX3	-352.0
KMT5B	-488.0
BRMS1	-568.0
H2AX	-614.0
ASH2L	-865.0
EZH2	-873.0
ARID5B	-1012.0
SUPT3H	-1042.0
ELP1	-1180.0
CCND1	-1519.0
HMG20B	-1643.0
PRMT3	-1663.0
RBBP5	-1889.0
PADI2	-1966.0
H2BC26	-2895.0
REST	-3392.0
PHF21A	-3413.0
ATF2	-3617.0
NFKB1	-3689.0
H2AZ2	-3800.0
RUVBL1	-4145.0
H2AC1	-4272.0
PRMT6	-4318.0
H2BC1	-4453.0
PADI6	-4528.0
PRDM9	-4793.0
H3C6	-4925.0
PADI1	-5084.0
SMARCE1	-5238.0
H2AC14	-5418.0
ACTL6B	-5469.0
TAF10	-5681.0
H2BC3	-5733.0
H4C16	-5871.0
SMARCD3	-6048.0
SETD6	-6164.0
PRDM16	-6191.0
PADI4	-6200.0
PADI3	-6417.0
H3C3	-6688.0
H2BC14	-7035.0
MECOM	-7108.0
H4C12	-7199.0
SETDB2	-7273.0
HDAC2	-7451.0
SUV39H2	-7539.0
H3C12	-7844.0

---

REACTOME_OLFACTORY_SIGNALING_PATHWAY

REACTOME_OLFACTORY_SIGNALING_PATHWAY

	628
set	REACTOME_OLFACTORY_SIGNALING_PATHWAY
setSize	348
pANOVA	8.36e-17
s.dist	-0.26
p.adjustANOVA	9.15e-15

Top enriched genes

Top 20 genes

GeneID	Gene Rank
OR56B4	-9736
OR8H3	-9724
OR4C12	-9723
OR1L1	-9702
OR52E6	-9696
OR8A1	-9673
OR6Q1	-9604
OR8B4	-9573
OR51A7	-9562
OR8G5	-9527
OR52E2	-9507
OR5A2	-9498
OR51T1	-9479
OR52I1	-9471
OR51M1	-9470
OR10K2	-9445
OR5H6	-9442
OR1S2	-9439
OR52R1	-9409
OR5I1	-9373

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
OR56B4	-9736.0
OR8H3	-9724.0
OR4C12	-9723.0
OR1L1	-9702.0
OR52E6	-9696.0
OR8A1	-9673.0
OR6Q1	-9604.0
OR8B4	-9573.0
OR51A7	-9562.0
OR8G5	-9527.0
OR52E2	-9507.0
OR5A2	-9498.0
OR51T1	-9479.0
OR52I1	-9471.0
OR51M1	-9470.0
OR10K2	-9445.0
OR5H6	-9442.0
OR1S2	-9439.0
OR52R1	-9409.0
OR5I1	-9373.0
OR51F1	-9365.0
OR5B17	-9363.0
OR5B21	-9348.0
OR51B6	-9326.0
OR52A1	-9301.0
OR2W3	-9286.0
OR13C4	-9239.0
OR56A1	-9221.0
OR6C4	-9210.0
OR9Q2	-9206.0
OR10W1	-9199.0
OR6V1	-9189.0
OR2S2	-9083.0
OR12D3	-9040.0
OR10G2	-9028.0
OR56B1	-9003.0
OR5M9	-8969.0
OR1A1	-8966.0
OR52N1	-8963.0
OR51L1	-8956.0
OR2H2	-8933.0
OR10S1	-8932.0
OR4D9	-8928.0
OR2F1	-8912.0
OR51G1	-8910.0
OR2B6	-8861.0
OR51D1	-8860.0
OR5B2	-8801.0
OR8B12	-8729.0
OR4A16	-8680.0
OR5T1	-8664.0
OR10V1	-8644.0
OR13C9	-8633.0
OR4M1	-8599.0
OR2T12	-8552.0
OR5T3	-8535.0
OR56A4	-8510.0
OR6X1	-8504.0
OR6C74	-8423.0
OR10G4	-8412.0
OR2G2	-8403.0
OR8S1	-8366.0
OR10J5	-8365.0
OR8U3	-8337.0
OR52A5	-8299.0
OR51F2	-8280.0
OR11A1	-8271.0
OR13F1	-8242.0
OR52B2	-8165.0
OR2AG1	-8148.0
OR6K2	-8132.0
OR8G1	-8101.0
OR4D11	-7998.0
OR9I1	-7876.0
OR4X2	-7875.0
OR5D14	-7847.0
OR1E2	-7846.0
OR2A12	-7817.0
OR5AK2	-7753.0
OR1E1	-7736.0
OR4K1	-7734.0
OR2V2	-7699.0
OR6Y1	-7666.0
OR5B12	-7665.0
OR1A2	-7658.0
OR6C3	-7638.0
OR14C36	-7537.0
OR10AG1	-7528.0
OR51I2	-7516.0
OR2L3	-7505.0
OR2AK2	-7455.0
OR52D1	-7336.0
OR4A5	-7302.0
OR9Q1	-7232.0
OR51E2	-7086.0
OR8J1	-7030.0
OR5W2	-7017.0
OR2M4	-7011.0
OR2L8	-6970.0
OR5V1	-6960.0
OR6B3	-6934.0
OR4K14	-6925.0
OR51Q1	-6890.0
OR1B1	-6810.0
OR8D4	-6763.0
OR8K5	-6747.0
OR5L1	-6742.0
OR6B1	-6729.0
OR2F2	-6511.0
OR5M10	-6469.0
OR6B2	-6370.0
OR4F15	-6368.0
OR9G4	-6299.0
OR11H6	-6298.0
OR52N2	-6218.0
OR52H1	-6217.0
OR10G7	-6210.0
OR4D2	-6181.0
OR8K3	-6108.0
OR10J1	-6099.0
OR4A47	-6082.0
REEP1	-6012.0
OR52I2	-6002.0
OR5AU1	-6001.0
OR51V1	-5752.0
OR51B5	-5717.0
OR5D16	-5706.0
OR52E8	-5666.0
OR2H1	-5590.0
OR2M2	-5497.0
OR8H1	-5453.0
OR5M1	-5443.0
OR2A2	-5426.0
OR6A2	-5417.0
OR6M1	-5267.0
OR5P3	-5207.0
ANO2	-4953.0
OR13J1	-4901.0
OR10A3	-4700.0
OR10A5	-4643.0
OR7G3	-4497.0
OR9A2	-4473.0
OR6C70	-4449.0
EBF1	-4384.0
OR1M1	-4357.0
OR2L13	-4284.0
OR1Q1	-4149.0
OR10H5	-4142.0
OR2AG2	-4080.0
OR10T2	-4011.0
OR9G1	-3975.5
OR9G9	-3975.5
OR14J1	-3970.0
OR5L2	-3847.0
OR10A4	-3841.0
OR5AP2	-3837.0
OR4K17	-3733.0
OR2Z1	-3625.0
OR4C15	-3621.0
OR7C1	-3529.0
OR5B3	-3459.0
OR1L3	-3426.0
OR5C1	-3381.0
OR2T8	-3367.0
OR1N1	-3317.0
OR10A6	-3312.0
OR6C68	-3299.0
OR13G1	-3283.0
OR4K13	-3241.0
OR51G2	-3223.0
OR5M3	-3215.0
OR2B2	-3109.0
OR1L4	-3081.0
OR10A7	-3076.0
OR14A16	-3017.0
OR6C2	-3003.0
OR2A5	-2883.0
OR10H1	-2810.0
OR11G2	-2738.0
OR2D2	-2736.0
OR52E4	-2734.0
CNGB1	-2670.0
OR52K2	-2659.0
OR2M3	-2650.0
GNG13	-2505.0
OR4B1	-2492.0
OR13C2	-2438.0
OR12D2	-2418.0
OR4E2	-2413.0
OR10G8	-2376.0
LHX2	-2314.0
OR5AC2	-2095.0
OR2G3	-2073.0
OR7A10	-2020.0
OR10X1	-1961.0
OR52M1	-1821.0
OR4C46	-1808.0
OR2T33	-1698.0
OR14I1	-1683.0
OR52K1	-1634.0
OR4L1	-1592.0
OR1F1	-1559.0
OR4A15	-1501.0
OR1C1	-1477.0
OR10H2	-1397.0
OR7G1	-1317.0
OR5H1	-1150.0
OR5AN1	-1129.0
OR1S1	-963.0
OR10A2	-951.0
OR51B4	-948.0
OR2M5	-912.0
OR1J2	-763.0
OR5F1	-686.0
OR2T4	-536.0
OR51I1	-304.0
OR5P2	-233.0
OR5D18	-100.0
OR2AT4	-72.0
OR5A1	20.0
OR2W1	21.0
OR5K4	162.0
OR2B3	177.0
OR51B2	232.0
OR51S1	253.0
OR56A3	277.0
OR8K1	335.0
OR6S1	355.0
OR2T3	514.0
OR5AS1	619.0
OR8U8	627.0
OR13A1	641.0
GNAL	654.0
OR5H2	896.0
OR6T1	1026.0
OR6K6	1146.0
OR52L1	1149.0
OR6K3	1160.0
RTP1	1178.0
OR2B11	1212.0
OR51A2	1236.0
OR4N2	1241.0
OR5K1	1379.0
OR56A5	1553.0
OR8J3	2079.0
OR3A1	2087.0
OR7G2	2140.0
OR4D10	2166.0
OR2G6	2295.0
OR5K2	2395.0
OR2T6	2511.0
OR2L2	2571.0
OR51E1	2601.0
OR1G1	2634.0
OR5J2	2727.0
OR4C45	2813.0
RTP2	2865.0
OR6C1	3033.0
OR52W1	3070.0
OR1L6	3092.0
OR2C1	3225.0
OR5T2	3242.0
OR10C1	3427.0
OR4D6	3430.0
OR10H3	3446.0
OR8D2	3450.0
OR6C75	3490.0
OR4K2	3738.0
ADCY3	3756.0
OR2C3	4192.0
OR5AR1	4229.0
OR10G9	4336.0
OR4C3	4356.0
OR5H15	4361.0
OR10P1	4394.0
OR9K2	4446.0
OR8U1	4489.0
OR2T1	4612.0
OR6P1	4761.0
CNGA4	4992.0
OR10K1	5185.0
OR4K15	5202.0
OR6C76	5358.0
OR13D1	5594.0
OR8B8	5627.0
OR5M11	5706.0
OR4F6	5788.0
LDB1	6071.0
OR7D4	6181.0
OR13C3	6620.0
OR2V1	6754.0
OR2T27	6829.0
OR4D5	7018.0
OR1I1	7124.0
OR9A4	7205.0
OR6C65	7257.0
OR10Q1	7303.0
OR6C6	7324.0
OR7C2	7372.0
OR2L5	7588.0
OR1D2	7792.0
OR2AP1	7828.0
OR7A17	7851.0
OR8B2	8130.0
OR4N5	8274.0
OR10AD1	8294.0
OR7D2	8295.0
OR4C16	8593.0
OR1L8	8661.0
OR4D1	8776.0
OR1K1	8830.0
OR2M7	8998.0
OR4S1	9096.0
OR10Z1	9194.0
OR4K5	9233.0
OR11H4	9335.0
OR6F1	9532.0
OR52J3	9822.0
OR2J2	10163.0
OR5M8	10201.0
OR2K2	10210.0
OR2A14	10276.0
OR10G3	10297.0
OR4C6	10320.0
OR10H4	10439.0
OR2T11	10578.0
OR13C8	10658.0
GNB1	10735.0
OR5K3	10777.0
OR3A2	11023.0
OR2Y1	11147.0
OR1J4	11187.0
OR1J1	11209.0
OR6N2	11236.0
OR7A5	11258.0
OR10J3	11316.0
OR4X1	11412.0
OR8D1	11570.0
OR2AE1	11606.0
OR5D13	11705.0
OR11L1	11728.0
OR1N2	11734.0
OR6N1	11737.0
OR2D3	11846.0
OR52B6	11933.0
OR8I2	12022.0
OR3A3	12056.0
OR7E24	12147.0

---

REACTOME_CELL_CYCLE_CHECKPOINTS

REACTOME_CELL_CYCLE_CHECKPOINTS

	1120
set	REACTOME_CELL_CYCLE_CHECKPOINTS
setSize	284
pANOVA	1.77e-15
s.dist	0.274
p.adjustANOVA	1.82e-13

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PIAS4	11883
H2BC15	11524
RANGAP1	11517
RCC2	11484
H4C5	11447
INCENP	11431
DYNLL2	11413
H2BC6	11322
ORC1	11169
PSMB4	11076
PPP2R1B	10998
UBE2V2	10901
PSMD4	10893
PSMD13	10870
RAD9A	10850
MCM7	10739
PPP2R5D	10733
AHCTF1	10728
PSMA2	10707
DYNC1H1	10679

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PIAS4	11883.0
H2BC15	11524.0
RANGAP1	11517.0
RCC2	11484.0
H4C5	11447.0
INCENP	11431.0
DYNLL2	11413.0
H2BC6	11322.0
ORC1	11169.0
PSMB4	11076.0
PPP2R1B	10998.0
UBE2V2	10901.0
PSMD4	10893.0
PSMD13	10870.0
RAD9A	10850.0
MCM7	10739.0
PPP2R5D	10733.0
AHCTF1	10728.0
PSMA2	10707.0
DYNC1H1	10679.0
YWHAE	10677.0
RPA1	10676.0
NSD2	10532.0
CDC23	10475.0
ANAPC15	10466.0
CENPN	10448.0
PSMC6	10418.0
PAFAH1B1	10395.0
CDCA8	10170.0
DYNC1LI2	10120.0
SGO1	10062.0
RMI2	10057.0
NUP85	10023.0
CENPF	10012.0
PSMD3	9979.0
CDC25C	9899.0
RMI1	9852.0
PSMD7	9804.0
PSMC4	9692.0
NSL1	9660.0
ANAPC1	9651.0
MCM2	9629.0
PSMD2	9598.0
YWHAG	9563.0
CENPS	9547.0
PSMB5	9461.0
BUB1B	9388.0
CDKN1B	9381.0
NUP133	9347.0
NUDC	9330.0
CLASP1	9232.0
UIMC1	9223.0
HERC2	9108.0
H4C6	9077.0
PSMF1	9002.0
CENPP	9001.0
ZWILCH	8932.0
PHF20	8925.0
H2BC10	8901.0
XPO1	8891.0
NDEL1	8779.0
BABAM1	8603.0
PSMB7	8555.0
PSMA4	8487.0
RFC2	8432.0
CLIP1	8310.0
H4C11	8241.0
PMF1	8197.0
CKAP5	8128.0
H4C13	8117.0
TOPBP1	8095.0
ANAPC16	8064.0
H4C1	8017.0
PSMB1	7978.0
PSMA6	7971.0
DNA2	7894.0
NUP98	7826.0
KNTC1	7772.0
BLM	7764.0
CDC45	7713.0
PSME2	7675.0
ANAPC4	7652.0
PSMD1	7564.0
ANAPC5	7558.0
H2BC4	7539.0
RPS27A	7499.0
PSME1	7470.0
COP1	7448.0
MCM8	7433.0
RBBP8	7402.0
H2BC9	7228.5
CDC27	7198.0
H4C8	7058.0
PSMA3	7039.0
MAD1L1	7020.0
PSMA1	6977.0
PSMD6	6942.0
DSN1	6888.0
KIF18A	6886.0
CDC16	6748.0
NUP37	6708.0
PSMB3	6665.0
PSMD11	6649.0
RNF8	6625.0
RPS27	6477.0
ZNF385A	6469.0
PSMD12	6422.0
PSMB6	6370.0
ANAPC10	6338.0
H2BC8	6334.0
NUP160	6322.0
NDE1	6318.0
PSMD5	6295.0
PSME3	6289.0
MCM4	6281.0
H2BC12	6220.0
MDM4	6157.0
CENPM	6069.0
CENPL	6013.0
YWHAQ	5997.0
PSMD9	5939.0
ANAPC11	5794.0
ORC5	5764.0
SEH1L	5744.0
CENPE	5720.0
CDC26	5692.0
CENPC	5654.0
CENPU	5624.0
ORC6	5505.0
TOP3A	5504.0
CDC6	5426.0
PSMB2	5390.0
UBC	5385.0
H4C3	5297.0
CENPK	5296.0
RPA2	5194.0
ORC3	5191.0
DYNC1LI1	5132.0
CENPQ	5131.0
MDM2	5073.0
RFC5	5072.0
PSMA7	5054.0
PPP2R5C	5016.0
KAT5	5000.0
CHEK1	4981.0
CLASP2	4967.0
RANBP2	4890.0
SEC13	4854.0
RFC4	4504.0
B9D2	4467.0
PSMA8	4378.0
PPP2R1A	4310.0
GTSE1	4307.0
KIF2A	4282.0
SGO2	4264.0
KIF2B	4249.0
DYNLL1	4203.0
MCM5	4177.0
PSMC2	4047.0
WRN	4033.0
RNF168	4001.0
H4C2	3987.0
PSMB10	3971.0
BUB3	3920.0
MCM3	3886.0
YWHAH	3875.0
BUB1	3874.0
BRIP1	3816.0
CENPO	3792.0
ANAPC7	3782.0
ZWINT	3720.0
TAOK1	3609.0
H4C4	3596.0
MRE11	3571.0
TP53	3499.0
PLK1	3472.0
UBE2E1	3470.0
ORC4	3333.0
PSMC3	3323.0
NUP107	3276.0
PSMC1	3148.0
RPA3	3146.0
PSME4	3137.0
PSMC5	3065.0
TP53BP1	3014.0
H2BC7	2792.5
BRCA1	2780.0
MIS12	2770.0
H2BC21	2718.0
RFC3	2692.0
CDKN1A	2387.0
PPP1CC	2315.0
PSMB8	2300.0
KNL1	2176.0
ATR	2151.0
RAD9B	2147.0
ATM	2137.0
CCNB1	2131.0
H2BC5	2100.0
PCBP4	2069.0
CHEK2	1906.0
PSMD14	1903.0
UBE2S	1865.0
H2BC17	1857.0
H2BC13	1834.0
CLSPN	1743.0
PSMB11	1723.0
PPP2R5A	1572.0
SKA2	1570.0
CDK1	1360.0
NDC80	1352.0
H2BC11	1286.0
YWHAZ	1179.0
RAD1	1126.0
CDC25A	1124.0
NUF2	899.0
AURKB	823.0
CDC20	611.0
NUP43	561.0
PPP2CB	497.0
ATRIP	448.0
PPP2R5B	256.0
CDKN2A	229.0
YWHAB	170.0
CCNB2	97.0
PPP2R5E	-53.0
MAPRE1	-157.0
BABAM2	-162.0
H4C9	-276.0
H2AX	-614.0
NBN	-689.0
WEE1	-761.0
KIF2C	-1021.0
ANAPC2	-1206.0
CENPA	-1250.0
RAD50	-1348.0
UBE2D1	-1471.0
MDC1	-1484.0
RHNO1	-1864.0
PKMYT1	-1881.0
ITGB3BP	-1974.0
CENPT	-2031.0
PPP2CA	-2084.0
UBA52	-2237.0
ORC2	-2295.0
CDK2	-2309.0
UBB	-2335.0
MCM10	-2444.0
MAD2L1	-2478.0
ZW10	-2497.0
ABRAXAS1	-2572.0
CDC7	-2614.0
CENPH	-2615.0
DYNC1I2	-2797.0
H2BC26	-2895.0
PSMB9	-2938.0
CCNE1	-2947.0
EXO1	-3131.0
BARD1	-3201.0
MCM6	-3207.0
CCNE2	-3373.0
RAD17	-3609.0
UBE2C	-3845.0
SPC25	-4088.0
CCNA1	-4120.0
PSMA5	-4331.0
H2BC1	-4453.0
SKA1	-4482.0
BIRC5	-4539.0
PSMD8	-5050.0
DYNC1I1	-5334.0
SPDL1	-5533.0
H3-4	-5699.0
H2BC3	-5733.0
H4C16	-5871.0
CCNA2	-5945.0
HUS1	-5999.0
DBF4	-6276.0
UBE2N	-6864.0
H2BC14	-7035.0
H4C12	-7199.0
SEM1	-7461.0
SPC24	-7608.0
SFN	-8574.0

---

REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

	1082
set	REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE
setSize	125
pANOVA	5.73e-15
s.dist	-0.404
p.adjustANOVA	5.54e-13

Top enriched genes

Top 20 genes

GeneID	Gene Rank
KRT16	-9729
LCE2B	-9688
LCE3A	-9586
KRT74	-9563
KRT78	-9433
LCE6A	-9410
KRT17	-9314
SPRR1A	-9303
KRT9	-9259
KRT71	-9222
KRT14	-9168
LIPN	-9162
SPINK9	-9125
CSTA	-9117
KRT79	-9057
KRT24	-8984
PI3	-8964
LCE1F	-8934
KRT32	-8922
SPRR2A	-8886

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
KRT16	-9729
LCE2B	-9688
LCE3A	-9586
KRT74	-9563
KRT78	-9433
LCE6A	-9410
KRT17	-9314
SPRR1A	-9303
KRT9	-9259
KRT71	-9222
KRT14	-9168
LIPN	-9162
SPINK9	-9125
CSTA	-9117
KRT79	-9057
KRT24	-8984
PI3	-8964
LCE1F	-8934
KRT32	-8922
SPRR2A	-8886
KRT76	-8877
KRT19	-8875
KRT7	-8765
KRT27	-8669
KLK12	-8668
CASP14	-8663
RPTN	-8620
DSG2	-8585
SPRR3	-8576
KRT18	-8526
KRT72	-8420
KRT23	-8416
SPRR2E	-8387
KRT37	-8329
LCE1B	-8307
FLG	-8228
LCE3E	-8172
DSC2	-8062
LCE4A	-8035
KLK13	-7818
LCE1C	-7815
KRT38	-7396
DSG1	-7296
KRT3	-7286
SPRR1B	-6979
KRT4	-6978
KRT75	-6835
KLK8	-6694
KRT81	-6666
DSG4	-6639
LCE3B	-6614
KRT31	-6546
KRT86	-6474
KRT15	-6470
KRT20	-6319
SPINK5	-6071
CELA2A	-5368
KRT84	-5331
KLK14	-5129
PKP3	-5051
LCE2D	-4950
LCE2A	-4834
KRT2	-4726
SPRR2D	-4680
CDSN	-4652
JUP	-4358
IVL	-4353
KRT40	-4045
SPINK6	-4009
KAZN	-3890
KLK5	-3849
KRT83	-3794
KRT33B	-3726
SPRR2G	-3470
KRT82	-3334
EVPL	-3257
DSC3	-2978
KRT10	-2870
KRT12	-2785
PKP1	-2665
PERP	-2247
KRT28	-2144
PCSK6	-2082
KRT8	-1922
KRT36	-1903
KRT85	-1758
KRT34	-1110
LIPJ	-734
KRT25	-394
KRT26	-62
PRSS8	102
KRT13	312
SPRR2F	341
PPL	727
PKP2	884
CAPNS1	967
LIPK	1477
KRT33A	2225
LCE3D	2278
DSG3	2280
DSP	2356
CAPN1	2455
KRT80	2463
PKP4	2931
KRT6C	3159
KRT35	3721
KRT73	4034
KRT5	4037
ST14	4464
KRT77	4576
KRT6B	5705
TCHH	6333
KRT6A	6595
DSC1	6986
LCE5A	7379
LCE1A	7487
KRT39	8886
FURIN	8913
LCE1E	9234
LELP1	9420
KRT1	9530
TGM5	11292
LIPM	11525
TGM1	11686
LCE2C	12081

---

REACTOME_DNA_REPAIR

REACTOME_DNA_REPAIR

	1168
set	REACTOME_DNA_REPAIR
setSize	321
pANOVA	9.65e-15
s.dist	0.251
p.adjustANOVA	8.8e-13

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PIAS4	11883
POLR2J	11816
SUMO3	11735
RNF4	11536
H2BC15	11524
SLX4	11491
H4C5	11447
POLR2A	11407
POLR2E	11395
H2BC6	11322
UBE2I	11138
XRCC3	11041
USP7	10931
UBE2V2	10901
NPLOC4	10876
H2AZ1	10867
ERCC3	10866
RAD9A	10850
POLD4	10789
PMS2	10704

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PIAS4	11883.0
POLR2J	11816.0
SUMO3	11735.0
RNF4	11536.0
H2BC15	11524.0
SLX4	11491.0
H4C5	11447.0
POLR2A	11407.0
POLR2E	11395.0
H2BC6	11322.0
UBE2I	11138.0
XRCC3	11041.0
USP7	10931.0
UBE2V2	10901.0
NPLOC4	10876.0
H2AZ1	10867.0
ERCC3	10866.0
RAD9A	10850.0
POLD4	10789.0
PMS2	10704.0
POLD1	10687.0
RPA1	10676.0
KDM4B	10657.0
PARP1	10610.0
YY1	10609.0
UBXN1	10582.0
NSD2	10532.0
FAN1	10456.0
POLR2B	10306.0
TINF2	10303.0
OGG1	10273.0
USP1	10261.0
NEIL2	10178.0
MCRS1	10068.0
RMI2	10057.0
EME1	10055.0
TIPIN	9916.0
RMI1	9852.0
PRPF19	9844.0
XAB2	9792.0
NTHL1	9737.0
CENPS	9547.0
H2AC4	9477.0
FANCI	9428.0
EP300	9390.0
ACTR8	9367.0
POLD2	9355.0
INO80	9340.0
TDG	9316.0
SIRT6	9227.0
UIMC1	9223.0
HERC2	9108.0
ASCC2	9084.0
H4C6	9077.0
BAZ1B	9069.0
DTL	9049.0
RAD52	9016.0
POLE	8933.0
H2BC10	8901.0
TCEA1	8796.0
COPS2	8678.0
RAD18	8649.0
USP45	8605.0
BABAM1	8603.0
LIG1	8548.0
COPS6	8496.0
CCNH	8458.0
POLR2H	8450.0
RFC2	8432.0
ACTL6A	8382.0
H2AC6	8277.0
H4C11	8241.0
UNG	8205.0
XRCC1	8165.0
UFD1	8151.0
H4C13	8117.0
TOPBP1	8095.0
H4C1	8017.0
FAAP100	7986.0
FANCL	7985.0
MUS81	7950.0
ALKBH5	7948.0
DNA2	7894.0
GEN1	7868.0
BLM	7764.0
H2AC8	7728.0
FANCM	7666.0
H2BC4	7539.0
COPS8	7530.0
NFRKB	7529.0
RPS27A	7499.0
ERCC4	7461.0
FANCD2	7450.0
PRKDC	7410.0
RBBP8	7402.0
POLL	7397.0
ELL	7361.0
H2BC9	7228.5
PPP4C	7201.0
PNKP	7101.0
ADPRS	7083.0
H4C8	7058.0
ACTR5	6978.0
ASCC1	6935.0
UBA7	6913.0
UBE2L6	6911.0
KPNA2	6903.0
COPS5	6872.0
PPIE	6843.0
TERF2IP	6812.0
ISY1	6808.0
XPC	6707.0
RNF8	6625.0
FEN1	6610.0
MLH1	6506.0
MSH2	6423.0
ALKBH3	6366.0
H2BC8	6334.0
XRCC5	6243.0
H2BC12	6220.0
ABL1	6174.0
SMARCA5	6154.0
CDK7	6114.0
DDB1	6110.0
ACTB	6053.0
FANCA	6008.0
RAD51B	5928.0
POLB	5870.0
CUL4A	5867.0
UBE2B	5859.0
FAAP24	5672.0
MUTYH	5658.0
POLI	5657.0
GTF2H3	5566.0
PCLAF	5557.0
TOP3A	5504.0
PAXIP1	5477.0
POLQ	5399.0
UBC	5385.0
H4C3	5297.0
FTO	5291.0
POLR2I	5214.0
RPA2	5194.0
MSH3	5190.0
H2AJ	5141.0
ERCC2	5135.0
NEIL3	5086.0
RFC5	5072.0
INO80E	5030.0
DCLRE1B	5022.0
KAT5	5000.0
POLR2G	4982.0
CHEK1	4981.0
SPRTN	4975.0
TDP1	4907.0
GTF2H1	4840.0
COPS7B	4815.0
KDM4A	4813.0
DCLRE1C	4771.0
APBB1	4741.0
DDB2	4656.0
POLR2F	4630.0
RFC4	4504.0
XRCC4	4468.0
UBE2T	4456.0
RIF1	4442.0
INO80D	4422.0
APEX1	4375.0
FANCG	4276.0
INO80C	4091.0
WRN	4033.0
RNF168	4001.0
H4C2	3987.0
COPS4	3879.0
PPP4R2	3859.0
USP43	3855.0
TERF1	3831.0
BRIP1	3816.0
UVSSA	3779.0
GTF2H5	3727.0
HMGN1	3680.0
RAD51AP1	3658.0
NEIL1	3629.0
H4C4	3596.0
MRE11	3571.0
PARP2	3563.0
TP53	3499.0
RAD51D	3495.0
RNF111	3481.0
H2AC20	3382.0
POLE3	3344.0
FANCF	3291.0
POLR2D	3258.0
TIMELESS	3151.0
RPA3	3146.0
PARG	3075.0
TP53BP1	3014.0
RAD51C	2979.0
H2AC18	2954.5
H2AC19	2954.5
TERF2	2921.0
ERCC6	2904.0
H2AC7	2792.5
H2BC7	2792.5
BRCA1	2780.0
H2BC21	2718.0
RFC3	2692.0
MGMT	2470.0
POLK	2462.0
ATR	2151.0
RAD9B	2147.0
ATM	2137.0
H2BC5	2100.0
GTF2H4	2092.0
CHEK2	1906.0
H2BC17	1857.0
H2BC13	1834.0
CLSPN	1743.0
SPIDR	1718.0
DCLRE1A	1679.0
INO80B	1555.0
COPS7A	1551.0
REV1	1427.0
ERCC5	1424.0
H2BC11	1286.0
TFPT	1282.0
RCHY1	1186.0
PALB2	1148.0
RAD1	1126.0
ZNF830	1115.0
POLN	1079.0
VCP	920.0
XRCC6	839.0
PPP5C	832.0
LIG4	829.0
SUMO2	766.0
WDR48	701.0
POLE2	695.0
REV3L	672.0
FAAP20	616.0
PCNA	570.0
FANCC	498.0
ATRIP	448.0
MPG	384.0
POLM	190.0
MBD4	90.0
USP10	79.0
RAD23A	46.0
AQR	42.0
BRCA2	38.0
RFC1	4.0
BABAM2	-162.0
ASCC3	-173.0
MSH6	-208.0
H4C9	-276.0
MNAT1	-336.0
POLH	-386.0
RAD23B	-510.0
TDP2	-544.0
H2AX	-614.0
NBN	-689.0
RAD51	-729.0
PIAS1	-1320.0
RAD50	-1348.0
MAPK8	-1441.0
MDC1	-1484.0
ALKBH2	-1513.0
TRIM25	-1558.0
POLD3	-1564.0
RTEL1	-1651.0
LIG3	-1660.0
POLR2L	-1678.0
POT1	-1694.0
EME2	-1830.0
XRCC2	-1852.0
RHNO1	-1864.0
EYA3	-1973.0
EYA1	-2154.0
ACD	-2160.5
COPS3	-2205.0
RBX1	-2227.0
UBA52	-2237.0
CDK2	-2309.0
UBB	-2335.0
ABRAXAS1	-2572.0
POLE4	-2612.0
H2BC26	-2895.0
CHD1L	-2926.0
EXO1	-3131.0
BARD1	-3201.0
MAD2L2	-3405.0
EYA2	-3460.0
SMUG1	-3530.0
SUMO1	-3539.0
RAD17	-3609.0
ERCC8	-3759.0
H2AZ2	-3800.0
POLR2K	-3852.0
BAP1	-3896.0
CCNA1	-4120.0
RUVBL1	-4145.0
H2BC1	-4453.0
ISG15	-4552.0
FANCE	-5071.0
H2AC14	-5418.0
NHEJ1	-5441.0
H3-4	-5699.0
H2BC3	-5733.0
PIAS3	-5823.0
H4C16	-5871.0
CCNA2	-5945.0
HUS1	-5999.0
POLR2C	-6018.0
EYA4	-6194.0
GPS1	-6560.0
UBE2N	-6864.0
H2BC14	-7035.0
H4C12	-7199.0
XPA	-7349.0
ERCC1	-7457.0
SEM1	-7461.0

---

REACTOME_DEUBIQUITINATION

REACTOME_DEUBIQUITINATION

	1000
set	REACTOME_DEUBIQUITINATION
setSize	260
pANOVA	2.18e-13
s.dist	0.264
p.adjustANOVA	1.88e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RNF123	11967
TAB1	11909
AXIN1	11805
WDR20	11739
TADA2B	11706
H2BC15	11524
MBD6	11516
H2BC6	11322
TGFBR1	11304
ABRAXAS2	11288
USP22	11278
TGFB1	11148
FOXK2	11092
PSMB4	11076
USP5	11026
USP7	10931
PSMD4	10893
PSMD13	10870
USP20	10779
KDM1B	10773

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RNF123	11967.0
TAB1	11909.0
AXIN1	11805.0
WDR20	11739.0
TADA2B	11706.0
H2BC15	11524.0
MBD6	11516.0
H2BC6	11322.0
TGFBR1	11304.0
ABRAXAS2	11288.0
USP22	11278.0
TGFB1	11148.0
FOXK2	11092.0
PSMB4	11076.0
USP5	11026.0
USP7	10931.0
PSMD4	10893.0
PSMD13	10870.0
USP20	10779.0
KDM1B	10773.0
RCE1	10746.0
PSMA2	10707.0
ARRB2	10636.0
H2AC15	10614.0
YY1	10609.0
PSMC6	10418.0
MUL1	10314.0
RNF135	10134.0
MCRS1	10068.0
FOXK1	10047.0
PSMD3	9979.0
OTUD3	9950.0
RIPK1	9907.0
H2AC12	9830.0
PSMD7	9804.0
USP18	9787.0
RIPK2	9756.0
PSMC4	9692.0
SMAD7	9613.0
SMURF2	9601.0
PSMD2	9598.0
H2AC4	9477.0
PSMB5	9461.0
EP300	9390.0
ACTR8	9367.0
INO80	9340.0
KAT2B	9295.0
UIMC1	9223.0
TRRAP	9187.0
TADA3	9149.0
ADRM1	9099.0
PSMF1	9002.0
H2BC10	8901.0
H2AC11	8737.0
USP42	8692.0
MAVS	8672.0
BABAM1	8603.0
JOSD1	8562.0
HGS	8560.0
PSMB7	8555.0
KAT2A	8511.0
PSMA4	8487.0
ACTL6A	8382.0
H2AC6	8277.0
UFD1	8151.0
USP19	8149.0
PSMB1	7978.0
PSMA6	7971.0
TOMM20	7910.0
USP34	7897.0
CYLD	7822.0
TRAF2	7733.0
H2AC8	7728.0
PSME2	7675.0
PSMD1	7564.0
H2BC4	7539.0
NFRKB	7529.0
RPS27A	7499.0
PSME1	7470.0
ATXN3	7354.0
USP21	7266.0
H2BC9	7228.5
TRIM4	7175.0
APC	7100.0
PSMA3	7039.0
ASXL2	7034.0
JOSD2	7012.0
ACTR5	6978.0
PSMA1	6977.0
PSMD6	6942.0
TNIP3	6910.0
H2AC17	6904.0
PTRH2	6850.0
USP8	6839.0
SNX3	6782.0
MAT2B	6771.0
ATXN7	6733.0
H2AC21	6681.0
SUDS3	6677.0
PSMB3	6665.0
PSMD11	6649.0
PSMD12	6422.0
PSMB6	6370.0
H2BC8	6334.0
STAM2	6329.0
PSMD5	6295.0
PSME3	6289.0
SIAH2	6239.0
H2BC12	6220.0
ZRANB1	6203.0
MDM4	6157.0
OTUD7B	6137.0
MYC	6135.0
ACTB	6053.0
RHOT1	6040.0
USP12	5987.0
PSMD9	5939.0
POLB	5870.0
TGFBR2	5792.0
SMAD2	5768.0
USP13	5634.0
UCHL3	5608.0
H2AC16	5532.0
PSMB2	5390.0
UBC	5385.0
USP16	5104.0
MDM2	5073.0
PSMA7	5054.0
INO80E	5030.0
DDB2	4656.0
USP4	4428.0
INO80D	4422.0
PSMA8	4378.0
VDAC3	4338.0
GATA3	4254.0
INO80C	4091.0
H2AC13	4085.0
PTEN	4078.0
PSMC2	4047.0
PSMB10	3971.0
TNIP1	3925.0
RNF146	3594.0
USP3	3574.0
MYSM1	3540.0
TP53	3499.0
USP47	3460.0
SMAD3	3402.0
H2AC20	3382.0
PSMC3	3323.0
BIRC2	3188.0
PSMC1	3148.0
PSME4	3137.0
PSMC5	3065.0
RHOA	3000.0
NEDD8	2985.0
H2AC18	2954.5
H2AC19	2954.5
H2AC7	2792.5
H2BC7	2792.5
BRCA1	2780.0
H2BC21	2718.0
TRAF3	2674.0
MAP3K7	2632.0
ASXL1	2591.0
USP15	2312.0
PSMB8	2300.0
USP28	2260.0
USP30	2233.0
USP2	2228.0
H2BC5	2100.0
TOMM70	2006.0
PSMD14	1903.0
H2BC17	1857.0
ESR1	1837.0
H2BC13	1834.0
CLSPN	1743.0
PSMB11	1723.0
KEAP1	1708.0
MBD5	1639.0
TNKS	1634.0
INO80B	1555.0
IDE	1444.0
CDK1	1360.0
H2AC25	1333.0
USP48	1328.0
H2BC11	1286.0
TFPT	1282.0
CDC25A	1124.0
UCHL5	1122.0
VCPIP1	1055.0
ARRB1	1053.0
TNFAIP3	1016.0
VCP	920.0
USP37	840.0
SMAD1	803.0
STAM	744.0
CCP110	730.0
WDR48	701.0
USP24	640.0
NLRP3	615.0
CDC20	611.0
STAMBP	580.0
NOD1	457.0
ADRB2	250.0
BECN1	214.0
TRAF6	213.0
USP33	120.0
USP10	79.0
RAD23A	46.0
USP14	-57.0
BABAM2	-162.0
SENP8	-323.0
RAD23B	-510.0
OTUB1	-534.0
FKBP8	-577.0
UCHL1	-774.0
VDAC2	-858.0
SKP2	-864.0
UBE2D1	-1471.0
TRIM25	-1558.0
USP25	-1706.0
UBA52	-2237.0
IFIH1	-2291.0
NFKBIA	-2315.0
UBB	-2335.0
BIRC3	-2406.0
ABRAXAS1	-2572.0
SMAD4	-2666.0
H2BC26	-2895.0
RIGI	-2937.0
PSMB9	-2938.0
YOD1	-2986.0
AXIN2	-3173.0
BARD1	-3201.0
VDAC1	-3516.0
NOD2	-3808.0
STAMBPL1	-3851.0
BAP1	-3896.0
CCNA1	-4120.0
RUVBL1	-4145.0
H2AC1	-4272.0
PSMA5	-4331.0
H2BC1	-4453.0
PRKN	-4525.0
HIF1A	-4580.0
OTUB2	-4629.0
TNIP2	-4650.0
TNKS2	-4742.0
PSMD8	-5050.0
H2AC14	-5418.0
USP49	-5664.0
TAF10	-5681.0
USP44	-5721.0
H2BC3	-5733.0
CCNA2	-5945.0
OTUD7A	-6203.0
H2BC14	-7035.0
SEM1	-7461.0
CFTR	-8343.0
IL33	-9101.0

---

REACTOME_MRNA_SPLICING

REACTOME_MRNA_SPLICING

	1143
set	REACTOME_MRNA_SPLICING
setSize	197
pANOVA	2.93e-13
s.dist	0.301
p.adjustANOVA	2.4e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PRPF8	11964
POLR2J	11816
SF1	11613
POLR2A	11407
POLR2E	11395
LSM4	11287
DHX16	11089
PPIH	11075
HNRNPM	11071
SF3A3	11001
CCDC12	10921
RBM42	10732
PPIL2	10648
PRPF38A	10583
PRPF18	10560
SUGP1	10559
FAM32A	10379
RBM5	10311
POLR2B	10306
TFIP11	10299

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PRPF8	11964
POLR2J	11816
SF1	11613
POLR2A	11407
POLR2E	11395
LSM4	11287
DHX16	11089
PPIH	11075
HNRNPM	11071
SF3A3	11001
CCDC12	10921
RBM42	10732
PPIL2	10648
PRPF38A	10583
PRPF18	10560
SUGP1	10559
FAM32A	10379
RBM5	10311
POLR2B	10306
TFIP11	10299
MAGOH	10284
SNRNP70	10173
SRRM2	10082
CHERP	9969
SNRPD2	9957
PUF60	9935
PRPF19	9844
XAB2	9792
DHX38	9776
SNRPN	9640
ZMAT5	9637
U2AF2	9577
YJU2	9562
HNRNPC	9537
SNRPB	9514
WBP4	9229
PRKRIP1	9222
FUS	9191
SNRPC	9188
DHX35	9177
PRPF6	9169
ALYREF	9167
DDX42	9106
MAGOHB	9064
LSM7	9054
SRRM1	9051
SRRT	8722
U2SURP	8710
SMU1	8708
GTF2F1	8571
BCAS2	8514
POLR2H	8450
SNRNP40	8019
SF3B3	8015
DHX8	7997
HNRNPA2B1	7955
BUD31	7838
DHX15	7710
TRA2B	7660
ZMAT2	7420
PPIL3	7267
LENG1	7253
NCBP2	7200
CTNNBL1	7140
SNRNP200	7133
SF3A1	7119
HNRNPK	7040
SF3B1	6993
CRNKL1	6918
PCBP1	6906
PPIE	6843
ISY1	6808
SAP18	6685
SRSF9	6509
HSPA8	6500
SF3B5	6491
LSM5	6394
SNRNP35	6383
RBM22	6330
PCBP2	6238
DDX41	6050
CDC40	6019
DDX23	6002
SRSF4	5719
RBM8A	5667
PPP1R8	5660
CWC22	5540
SLU7	5533
CACTIN	5479
SF3A2	5350
POLR2I	5214
POLR2G	4982
UBL5	4931
HNRNPL	4884
SNIP1	4872
DHX9	4737
POLR2F	4630
CWC25	4619
BUD13	4481
RNPC3	4386
SRSF6	4301
WDR70	4297
PRPF4	4243
SNRPF	4099
PNN	3997
MFAP1	3988
SRSF11	3965
SNRPE	3915
LSM3	3863
IK	3839
WBP11	3834
HNRNPD	3781
HNRNPA1	3775
HNRNPU	3733
SNRPD3	3606
TCERG1	3568
HNRNPR	3555
PDCD7	3497
POLR2D	3258
MTREX	3213
SRSF1	3201
PRPF31	3198
PPIG	2920
SART1	2847
SNRNP48	2803
SMNDC1	2785
ACIN1	2707
SRSF5	2693
PPIL1	2651
DDX39B	2621
GCFC2	2535
CDC5L	2274
SNRPA1	2271
SRSF3	2267
SNRPD1	2163
NSRP1	2065
LUC7L3	1957
SNRPG	1899
HNRNPF	1897
CWC15	1872
RBM17	1870
DDX5	1755
SF3B2	1722
SDE2	1612
DDX46	1605
RBM39	1598
PRPF3	1597
RBM25	1564
PPWD1	1484
PTBP1	1402
PRPF40A	1393
SNRNP25	1361
CASC3	1351
U2AF1L4	1290
SRSF12	1262
ZNF830	1115
LSM6	951
C9orf78	789
HNRNPA3	428
PPIL4	417
LSM8	333
CCAR1	199
LSM2	163
EIF4A3	121
CWC27	91
AQR	42
NCBP1	-175
TXNL4A	-184
CWF19L2	-492
SNRPB2	-564
HNRNPH1	-594
EFTUD2	-937
ZCRB1	-1100
SNRPA	-1139
YBX1	-1287
GTF2F2	-1392
SRSF7	-1396
SNU13	-1463
DNAJC8	-1502
GPATCH1	-1626
POLR2L	-1678
USP39	-1751
RBM7	-1970
SF3B4	-2190
SYF2	-2735
SRSF10	-2873
SRSF2	-3015
PLRG1	-3701
POLR2K	-3852
RNPS1	-3954
PRCC	-4201
SNW1	-4266
PHF5A	-4818
POLR2C	-6018
SF3B6	-6121
SNRNP27	-6233
SRSF8	-8657

---

REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE

REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE

	500
set	REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE
setSize	228
pANOVA	1.02e-12
s.dist	0.274
p.adjustANOVA	7.97e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RANGAP1	11517
RCC2	11484
INCENP	11431
DYNLL2	11413
ESPL1	11271
UBE2I	11138
PSMB4	11076
PPP2R1B	10998
PSMD4	10893
SPAST	10889
PSMD13	10870
CHMP4B	10836
PPP2R5D	10733
AHCTF1	10728
PSMA2	10707
DYNC1H1	10679
CDC23	10475
ANAPC15	10466
CENPN	10448
PSMC6	10418

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RANGAP1	11517
RCC2	11484
INCENP	11431
DYNLL2	11413
ESPL1	11271
UBE2I	11138
PSMB4	11076
PPP2R1B	10998
PSMD4	10893
SPAST	10889
PSMD13	10870
CHMP4B	10836
PPP2R5D	10733
AHCTF1	10728
PSMA2	10707
DYNC1H1	10679
CDC23	10475
ANAPC15	10466
CENPN	10448
PSMC6	10418
PAFAH1B1	10395
CDCA8	10170
NUP62	10167
DYNC1LI2	10120
SGO1	10062
NUP85	10023
CENPF	10012
PSMD3	9979
NUP54	9855
PSMD7	9804
PSMC4	9692
NSL1	9660
ANAPC1	9651
PSMD2	9598
CENPS	9547
PSMB5	9461
BUB1B	9388
NUP133	9347
NUDC	9330
CC2D1B	9258
CLASP1	9232
SIRT2	9115
PSMF1	9002
CENPP	9001
ZWILCH	8932
CHMP2A	8906
XPO1	8891
STAG1	8828
BANF1	8827
NDEL1	8779
PSMB7	8555
LEMD2	8502
NUP93	8494
PSMA4	8487
CLIP1	8310
CHMP2B	8258
POM121	8233
SMC3	8217
PMF1	8197
CDCA5	8184
NUP58	8140
CKAP5	8128
ANAPC16	8064
CHMP4A	8022
PSMB1	7978
PSMA6	7971
NUP98	7826
KNTC1	7772
PSME2	7675
ANAPC4	7652
PSMD1	7564
ANAPC5	7558
RPS27A	7499
LBR	7494
PSME1	7470
CDC27	7198
PSMA3	7039
MAD1L1	7020
PSMA1	6977
PSMD6	6942
DSN1	6888
KIF18A	6886
CDC16	6748
NUP37	6708
PSMB3	6665
PSMD11	6649
RPS27	6477
PDS5A	6446
PSMD12	6422
PSMB6	6370
ANAPC10	6338
NUP160	6322
NDE1	6318
PSMD5	6295
PSME3	6289
CENPM	6069
CENPL	6013
PSMD9	5939
ANAPC11	5794
VPS4A	5772
SEH1L	5744
ANKLE2	5726
CENPE	5720
CDC26	5692
CENPC	5654
CENPU	5624
PSMB2	5390
UBC	5385
CENPK	5296
DYNC1LI1	5132
CENPQ	5131
CHMP7	5074
RAN	5055
PSMA7	5054
PPP2R5C	5016
CLASP2	4967
RANBP2	4890
SEC13	4854
RCC1	4850
WAPL	4638
B9D2	4467
PSMA8	4378
CHMP6	4359
PPP2R1A	4310
KIF2A	4282
SGO2	4264
KIF2B	4249
TUBA4A	4239
DYNLL1	4203
TUBB2A	4122
PSMC2	4047
PSMB10	3971
BUB3	3920
TUBB2B	3907
BUB1	3874
TUBA4B	3811
CENPO	3792
ANAPC7	3782
CHMP3	3762
ZWINT	3720
TNPO1	3709
TAOK1	3609
PLK1	3472
UBE2E1	3470
PSMC3	3323
NUP107	3276
LEMD3	3263
PSMC1	3148
PSME4	3137
NDC1	3079
PSMC5	3065
VRK2	2848
MIS12	2770
IST1	2752
NUP188	2493
NUP35	2378
TUBB4B	2340
PPP1CC	2315
PSMB8	2300
KNL1	2176
CCNB1	2131
PSMD14	1903
UBE2S	1865
PSMB11	1723
PPP2R5A	1572
SKA2	1570
CDK1	1360
NDC80	1352
LMNB1	1327
TUBA1A	1018
NUF2	899
AURKB	823
CDC20	611
PDS5B	610
NUP43	561
PPP2CB	497
NUP205	331
PPP2R5B	256
TUBB6	150
CCNB2	97
KPNB1	32
PPP2R5E	-53
TMPO	-93
MAPRE1	-157
TUBB4A	-357
TUBA8	-372
FBXO5	-747
KIF2C	-1021
ANAPC2	-1206
CENPA	-1250
UBE2D1	-1471
PPP2R2A	-1648
ITGB3BP	-1974
CENPT	-2031
PTTG1	-2060
PPP2CA	-2084
UBA52	-2237
UBB	-2335
MAD2L1	-2478
ZW10	-2497
CENPH	-2615
DYNC1I2	-2797
PSMB9	-2938
NUP155	-3213
RAD21	-3318
SUMO1	-3539
TUBA3D	-3545
TUBA1C	-3556
UBE2C	-3845
TUBB3	-4002
SPC25	-4088
PSMA5	-4331
SKA1	-4482
BIRC5	-4539
TUBA3E	-4662
VRK1	-4983
PSMD8	-5050
DYNC1I1	-5334
SPDL1	-5533
TUBA1B	-6340
TUBB1	-6519
LMNA	-6774
CHMP4C	-6820
TUBA3C	-7269
TUBAL3	-7278
SEM1	-7461
SPC24	-7608
TUBB8	-8942

---

REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS

REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS

	176
set	REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS
setSize	127
pANOVA	5.74e-12
s.dist	0.354
p.adjustANOVA	4.29e-10

Top enriched genes

Top 20 genes

GeneID	Gene Rank
LCK	11904
CD28	11682
AP2M1	11598
RANGAP1	11517
AP2A2	11289
PSMB4	11076
PSMD4	10893
RAE1	10890
PSMD13	10870
PSMA2	10707
AP1B1	10665
ELOB	10535
NUP210	10455
PSMC6	10418
PAK2	10228
NUP62	10167
NUP85	10023
PSMD3	9979
NUP54	9855
PSMD7	9804

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
LCK	11904
CD28	11682
AP2M1	11598
RANGAP1	11517
AP2A2	11289
PSMB4	11076
PSMD4	10893
RAE1	10890
PSMD13	10870
PSMA2	10707
AP1B1	10665
ELOB	10535
NUP210	10455
PSMC6	10418
PAK2	10228
NUP62	10167
NUP85	10023
PSMD3	9979
NUP54	9855
PSMD7	9804
CD247	9759
PSMC4	9692
AP1M2	9672
PSMD2	9598
NUP88	9522
PPIA	9515
PSMB5	9461
RAC1	9456
NUP133	9347
BTRC	9324
PSMF1	9002
XPO1	8891
BANF1	8827
APOBEC3G	8739
CCNT1	8657
PSMB7	8555
NUP93	8494
PSMA4	8487
POM121	8233
NUP50	8160
AAAS	8159
NUP58	8140
PSMB1	7978
PSMA6	7971
NUP98	7826
AP2S1	7803
PSME2	7675
PSMD1	7564
RPS27A	7499
PSME1	7470
PSMA3	7039
PSMA1	6977
PSMD6	6942
NUP37	6708
PSMB3	6665
PSMD11	6649
TPR	6489
PSMD12	6422
PSMB6	6370
NUP160	6322
PSMD5	6295
PSME3	6289
PSMD9	5939
SLC25A4	5865
AP1M1	5820
PACS1	5766
SEH1L	5744
AP2A1	5736
PSMB2	5390
UBC	5385
NUP42	5371
RAN	5055
PSMA7	5054
RANBP2	4890
SEC13	4854
RCC1	4850
NUP214	4833
DOCK2	4642
PSMA8	4378
AP2B1	4341
PSMC2	4047
ELMO1	4026
PSMB10	3971
CUL5	3961
SKP1	3705
CD8B	3697
PSMC3	3323
NUP107	3276
AP1S3	3259
PSMC1	3148
PSME4	3137
NDC1	3079
PSMC5	3065
ATP6V1H	3050
ELOC	2833
NUP188	2493
NUP35	2378
PSMB8	2300
POM121C	2036
PSMD14	1903
ARF1	1827
PSMB11	1723
AP1S1	908
HCK	797
NUP43	561
NUP205	331
FYN	61
KPNB1	32
KPNA1	-925
AP1G1	-1050
CDK9	-1861
RANBP1	-1938
PSIP1	-1996
RBX1	-2227
UBA52	-2237
NPM1	-2297
UBB	-2335
NUP153	-2541
PSMB9	-2938
NUP155	-3213
CD4	-4035
PSMA5	-4331
HLA-A	-4744
PSMD8	-5050
B2M	-7174
SEM1	-7461
HMGA1	-7614

---

REACTOME_NEURONAL_SYSTEM

REACTOME_NEURONAL_SYSTEM

	34
set	REACTOME_NEURONAL_SYSTEM
setSize	388
pANOVA	9.22e-12
s.dist	-0.202
p.adjustANOVA	6.58e-10

Top enriched genes

Top 20 genes

GeneID	Gene Rank
KCNA10	-9564
HTR3C	-9290
TUBB8	-8942
CACNG4	-8641
CHRNA1	-8550
KCNK17	-8355
CHRNB4	-8324
KCNV1	-8316
KCNJ4	-8137
CACNA2D3	-8099
GNG8	-8059
SLITRK6	-8023
GABRA6	-8002
PRKAR2B	-7999
NLGN1	-7987
GRIN3A	-7930
KCNK4	-7897
GABRG2	-7878
SLC5A7	-7864
KCNK3	-7812

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
KCNA10	-9564
HTR3C	-9290
TUBB8	-8942
CACNG4	-8641
CHRNA1	-8550
KCNK17	-8355
CHRNB4	-8324
KCNV1	-8316
KCNJ4	-8137
CACNA2D3	-8099
GNG8	-8059
SLITRK6	-8023
GABRA6	-8002
PRKAR2B	-7999
NLGN1	-7987
GRIN3A	-7930
KCNK4	-7897
GABRG2	-7878
SLC5A7	-7864
KCNK3	-7812
SLC6A12	-7798
SLITRK5	-7785
KCNK18	-7769
KCNG1	-7741
SLC6A11	-7713
KCND3	-7693
LRFN2	-7680
GRM5	-7657
SHANK2	-7640
LRFN3	-7514
KCND2	-7480
KCNK16	-7412
KCNJ6	-7344
CAMK2A	-7340
KCNS1	-7306
ADCY5	-7301
TUBAL3	-7278
TUBA3C	-7269
GABRA5	-7251
SLC1A1	-7223
KCNMA1	-7191
SLC18A3	-7169
GABRB1	-7165
KCNK9	-7140
SYT10	-7110
GABRB3	-7089
KCNMB4	-7084
SLC6A13	-7046
ADCY8	-6973
GRM1	-6953
NRXN1	-6919
GRIK4	-6909
VAMP2	-6867
NRXN3	-6854
LRRTM1	-6849
GLRB	-6824
KCNA4	-6789
BCHE	-6788
KCNN2	-6754
ADCY1	-6750
GRIK2	-6749
LRRTM4	-6720
CACNA1E	-6704
KCNK1	-6692
LRRC7	-6680
DLGAP1	-6616
GRIA4	-6615
TUBB1	-6519
SYN2	-6489
KCNK10	-6387
TUBA1B	-6340
NRG1	-6317
DLG2	-6314
SLC32A1	-6294
APBA1	-6288
NCALD	-6256
PTPRD	-6249
NTRK3	-6211
ADCY2	-6209
GRIN2C	-6205
CHRNA3	-6022
GRIA1	-6007
SYT7	-5910
NBEA	-5883
NRXN2	-5867
GRIK1	-5860
KCNMB2	-5794
ABCC9	-5776
ERBB4	-5774
KCNS2	-5743
GLUL	-5725
LRRTM3	-5716
PRKAG3	-5700
KCNJ16	-5686
SLITRK3	-5661
HTR3D	-5653
SLC1A6	-5643
HCN1	-5634
KCNA6	-5580
CHAT	-5528
CHRNA4	-5506
KCNJ9	-5496
HTR3B	-5476
KCNJ3	-5448
PLCB1	-5407
KCNK13	-5351
NEFL	-5340
PPFIA4	-5318
KCNH5	-5310
PPFIA2	-5279
GRIK3	-5275
LIN7A	-5262
KCNN4	-5250
GABBR2	-5243
CACNG3	-5212
CAMK2B	-5202
LRFN4	-5197
KCNH6	-5180
KCNJ5	-5166
EPB41L3	-5088
KCNH1	-5022
GLRA3	-5003
KCNJ10	-4991
KCNAB1	-4966
PRKAA2	-4922
RASGRF2	-4909
CAMK2D	-4902
MYO6	-4877
RIMS1	-4860
ABAT	-4754
KCNG3	-4729
KCNB2	-4721
SYN3	-4719
KCNJ2	-4696
TUBA3E	-4662
CPLX1	-4648
SYT1	-4532
DLGAP4	-4411
DLGAP3	-4338
PDLIM5	-4096
KCNS3	-4082
CACNB2	-4078
KCNH8	-4027
TUBB3	-4002
GABRA2	-3961
SLC17A7	-3945
EPB41L1	-3943
CACNA1B	-3930
CACNB4	-3904
KCNH3	-3813
UNC13B	-3792
SYT9	-3764
KCNJ12	-3706
CACNG8	-3695
KCNA1	-3661
PANX1	-3632
KCNV2	-3606
GABRA1	-3602
KCNH7	-3584
KCNG4	-3578
TUBA1C	-3556
TUBA3D	-3545
GRIN2A	-3522
CACNA2D2	-3503
KCNB1	-3421
KCNQ3	-3205
ABCC8	-3197
KRAS	-3161
KCNMB3	-3144
SLC22A1	-3120
STXBP1	-3057
NPTN	-2990
KCNJ15	-2940
CACNG2	-2904
GNG12	-2840
CAMKK1	-2814
ACHE	-2713
BEGAIN	-2710
GJC1	-2689
GRIA2	-2588
CACNA1A	-2585
PLCB2	-2536
GNG13	-2505
ALDH2	-2443
SYT2	-2401
KCNJ1	-2348
TSPOAP1	-2345
RAB3A	-2300
MAPT	-2262
SLITRK1	-2242
CAMK4	-2240
NRAS	-2230
GABRG3	-2194
NSF	-2180
KCNA5	-2167
PRKCG	-2163
GRIN2B	-2027
PPM1E	-2019
GABRB2	-1954
ARL6IP5	-1918
SHANK1	-1865
GAD1	-1857
GRIN1	-1851
HTR3A	-1797
KCNK2	-1793
KCNQ1	-1719
NRGN	-1669
KCNQ4	-1658
PRKACB	-1645
PPM1F	-1640
SLC1A2	-1613
SLC22A2	-1593
HOMER3	-1588
KCNJ11	-1575
SLC6A4	-1431
AKAP5	-1398
GRIP2	-1374
KCNH4	-1326
SYT12	-1268
EPB41L2	-1221
KCNN3	-1145
ADCY6	-1112
RPS6KA1	-1030
CHRND	-775
GIT1	-596
CHRNB2	-537
APBA3	-526
GNG4	-501
SLC6A3	-493
TUBA8	-372
TUBB4A	-357
LRFN1	-349
DLGAP2	-326
KCNJ8	-246
ALDH5A1	-164
DLG4	-148
SLC6A1	-135
GNAI1	-91
PPFIBP1	-54
EPB41L5	-33
STX1A	31
KCNC1	53
IL1RAP	111
GRIK5	114
TUBB6	150
SLC1A7	224
CHRNA7	296
KCNN1	314
SIPA1L1	445
HOMER1	513
HTR3E	515
DLG1	584
KCNC2	585
GNAL	654
SLC1A3	781
KCNQ2	782
GJD2	810
KCNC3	857
GNAI3	892
SLC38A1	930
PPFIA3	1006
TUBA1A	1018
GAD2	1092
GABRA4	1127
KCNF1	1251
ACTN2	1294
KCNA3	1530
KCNC4	1567
LRRTM2	1629
GLS2	1688
GRIP1	1709
LRRC4B	1739
GABBR1	1835
PTPRS	1863
PANX2	1877
KCNA2	2009
RPS6KA2	2023
NLGN2	2051
ADCY9	2080
CHRNA2	2210
GLRA1	2232
CACNB3	2334
TUBB4B	2340
APBA2	2579
PRKAG1	2584
PLCB3	2587
PPFIBP2	2646
CHRNE	2759
KCNH2	2804
HOMER2	2869
PRKAR1B	3218
RASGRF1	3375
GJA10	3396
CHRNB3	3440
KCNG2	3710
ADCY3	3756
TUBA4B	3811
HRAS	3837
HCN4	3846
CAMK1	3893
TUBB2B	3907
KCNMB1	4000
TUBB2A	4122
TUBA4A	4239
AP2B1	4341
ADCY4	4346
LIN7C	4352
KCNAB3	4372
PRKAR1A	4512
KIF17	4620
GABRR3	4643
KCNA7	4751
KCNQ5	4949
COMT	4955
GABRR1	4963
MDM2	5073
CHRNA9	5091
SNAP25	5125
EPB41	5238
GNAT3	5265
PRKAG2	5343
ARHGEF7	5367
GNB5	5393
GNB4	5421
NAAA	5481
LIN7B	5512
PTPRF	5590
GNG3	5611
AP2A1	5736
MAPK1	5826
PRKCA	5835
GRIN2D	5846
PRKAR2A	5856
PRKAA1	5866
GNB2	5886
LRTOMT	6029
GNG2	6075
GNG7	6169
HSPA8	6500
PRKCB	6744
GNG5	6795
KPNA2	6903
CHRNA5	7327
PICK1	7431
MAPK3	7526
KCNJ14	7542
CHRNG	7602
HCN2	7635
CAMKK2	7645
PRKAB2	7695
FLOT2	7786
AP2S1	7803
CHRNA6	7974
GLS	7990
SHARPIN	8046
GNGT1	8221
GNG10	8565
FLOT1	8646
CREB1	8716
HCN3	8774
GNAI2	8783
SLC18A2	8977
PRKACA	9014
GNG11	9097
CALM1	9105
KCNAB2	9453
RAC1	9456
SRC	9630
PRKAB1	9761
SLC38A2	10144
GNB3	10486
CAMK2G	10508
GRIN3B	10575
RTN3	10590
GNB1	10735
GNGT2	10852
GABRR2	10882
CACNB1	10970
PPFIA1	11132
DNAJC5	11192
AP2A2	11289
KCNK7	11363
ADCY7	11370
PRKACG	11518
AP2M1	11598
KCNK6	11603
DBNL	11730
PDPK1	11829

---

REACTOME_HATS_ACETYLATE_HISTONES

REACTOME_HATS_ACETYLATE_HISTONES

	551
set	REACTOME_HATS_ACETYLATE_HISTONES
setSize	129
pANOVA	3.12e-11
s.dist	0.338
p.adjustANOVA	2.13e-09

Top enriched genes

Top 20 genes

GeneID	Gene Rank
BRD1	12058
CREBBP	11715
TADA2B	11706
BRPF1	11679
YEATS2	11543
H2BC15	11524
H4C5	11447
H2BC6	11322
USP22	11278
ATXN7L3	11009
SUPT7L	10771
H2AC15	10614
SGF29	10387
EPC1	10250
ELP3	10211
MCRS1	10068
H2AC12	9830
TADA1	9720
KANSL3	9638
ELP2	9590

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
BRD1	12058.0
CREBBP	11715.0
TADA2B	11706.0
BRPF1	11679.0
YEATS2	11543.0
H2BC15	11524.0
H4C5	11447.0
H2BC6	11322.0
USP22	11278.0
ATXN7L3	11009.0
SUPT7L	10771.0
H2AC15	10614.0
SGF29	10387.0
EPC1	10250.0
ELP3	10211.0
MCRS1	10068.0
H2AC12	9830.0
TADA1	9720.0
KANSL3	9638.0
ELP2	9590.0
WDR5	9587.0
H2AC4	9477.0
EP300	9390.0
DMAP1	9370.0
JADE1	9302.0
KAT2B	9295.0
TRRAP	9187.0
EP400	9151.0
TADA3	9149.0
SAP130	9133.0
H4C6	9077.0
PHF20	8925.0
H3C11	8908.0
H2BC10	8901.0
KANSL1	8856.0
ING3	8816.0
KAT6A	8784.0
H2AC11	8737.0
KAT2A	8511.0
HAT1	8471.0
ACTL6A	8382.0
H2AC6	8277.0
H4C11	8241.0
ING4	8200.0
H4C13	8117.0
H4C1	8017.0
H2AC8	7728.0
H2BC4	7539.0
H3C1	7395.0
H2BC9	7228.5
H3C7	7228.5
H4C8	7058.0
H2AC17	6904.0
KAT6B	6861.0
KANSL2	6858.0
ATXN7	6733.0
H2AC21	6681.0
H3C10	6652.0
CLOCK	6442.0
H2BC8	6334.0
H2BC12	6220.0
ACTB	6053.0
H3C4	5911.0
TAF6L	5881.0
BRD8	5815.0
MEAF6	5790.0
MSL1	5775.0
MBIP	5641.0
ENY2	5568.0
H2AC16	5532.0
KAT7	5499.0
RUVBL2	5400.0
H4C3	5297.0
KAT5	5000.0
ELP6	4905.0
JADE2	4889.0
MRGBP	4760.0
MORF4L1	4333.0
H2AC13	4085.0
BRPF3	4071.0
H4C2	3987.0
H4C4	3596.0
H3C8	3521.0
TAF5L	3386.0
H2AC20	3382.0
TADA2A	3257.0
H2AC18	2954.5
H2AC19	2954.5
ZZZ3	2898.0
H2AC7	2792.5
H2BC7	2792.5
NCOA2	2754.0
H2BC21	2718.0
SUPT20H	2564.0
ELP5	2317.0
H2BC5	2100.0
ING5	2015.0
H2BC17	1857.0
TAF12	1849.0
H2BC13	1834.0
H3C2	1828.0
ELP4	1806.0
MSL2	1591.0
DR1	1339.0
H2AC25	1333.0
H2BC11	1286.0
NCOA1	1280.0
KAT8	1130.0
YEATS4	145.0
TAF9	-183.0
H4C9	-276.0
VPS72	-342.0
PAX3	-352.0
SUPT3H	-1042.0
ELP1	-1180.0
H2BC26	-2895.0
ATF2	-3617.0
RUVBL1	-4145.0
H2AC1	-4272.0
H2BC1	-4453.0
H3C6	-4925.0
H2AC14	-5418.0
TAF10	-5681.0
H2BC3	-5733.0
H4C16	-5871.0
H3C3	-6688.0
H2BC14	-7035.0
H4C12	-7199.0
H3C12	-7844.0

---

REACTOME_MEMBRANE_TRAFFICKING

REACTOME_MEMBRANE_TRAFFICKING

	374
set	REACTOME_MEMBRANE_TRAFFICKING
setSize	603
pANOVA	3.93e-11
s.dist	0.157
p.adjustANOVA	2.58e-09

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PREB	12151
MAN2A2	11884
CSNK1D	11871
CHML	11857
EPS15L1	11836
CLTB	11804
SBF1	11783
GOLGA1	11745
MYH9	11645
AP2M1	11598
TRAPPC10	11541
DYNLL2	11413
SEC22A	11390
CYTH2	11290
AP2A2	11289
SEC24B	11267
ARFRP1	11259
YKT6	11228
LDLRAP1	11193
ARL1	11164

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PREB	12151
MAN2A2	11884
CSNK1D	11871
CHML	11857
EPS15L1	11836
CLTB	11804
SBF1	11783
GOLGA1	11745
MYH9	11645
AP2M1	11598
TRAPPC10	11541
DYNLL2	11413
SEC22A	11390
CYTH2	11290
AP2A2	11289
SEC24B	11267
ARFRP1	11259
YKT6	11228
LDLRAP1	11193
ARL1	11164
EPN1	11094
CBL	11060
PPP6C	11008
AAK1	10995
AGPAT3	10965
GGA3	10949
HPS1	10944
DCTN3	10909
HPS4	10907
CTSZ	10840
CHMP4B	10836
ARFGAP1	10813
DYNC1H1	10679
YWHAE	10677
AP1B1	10665
RAB11B	10646
ARRB2	10636
SH3GL1	10596
DENND1C	10564
PUM1	10537
TBC1D10C	10534
COG1	10467
PAFAH1B1	10395
COPA	10390
PLIN3	10369
CLINT1	10365
KIF22	10355
DNM2	10321
RAB5C	10317
LMAN2	10309
USE1	10237
NAPA	10236
DENND2D	10195
TXNDC5	10130
DYNC1LI2	10120
CYTH1	10054
TOR1B	10050
DENND3	9970
KIF18B	9967
CD3D	9948
TBC1D10A	9923
SURF4	9903
KLC1	9809
AKT1	9802
PRKAB1	9761
RAB3IP	9753
MYO1C	9714
TBC1D2	9694
GJA9	9680
AP1M2	9672
KDELR3	9657
SRC	9630
COPG1	9572
YWHAG	9563
GOLGA2	9561
CTTN	9493
RINL	9484
GAK	9470
RAC1	9456
RAB21	9447
CPD	9432
STX10	9414
M6PR	9412
EPN2	9391
CD59	9356
ARPC3	9321
BLOC1S6	9292
RAB7A	9267
TBC1D13	9247
SEC24C	9238
EXOC7	9225
TBC1D1	9127
CALM1	9105
KLC4	9104
VPS37C	9072
RAB8A	9068
VPS37B	9063
CD55	9018
SEC23IP	8993
COPE	8985
EPGN	8950
GRB2	8934
CHMP2A	8906
DNASE2	8848
GGA2	8823
RABGEF1	8731
ARPC2	8695
ASPSCR1	8693
COPS2	8678
GJB3	8614
HGS	8560
MAN2A1	8557
DENND6A	8553
MON1B	8552
IL7R	8534
TMED10	8519
EXOC3	8510
COPS6	8496
KIF13B	8489
ARPC4	8481
SEC16A	8479
VPS4B	8449
KLC2	8445
AKT2	8422
RAB3GAP1	8366
SYT11	8305
CHMP2B	8258
TBC1D14	8191
CHMP4A	8022
TBC1D24	8006
TMEM115	7987
CAPZB	7951
VPS28	7949
SYNJ2	7889
SEC22B	7883
NBAS	7879
TRAPPC11	7808
AP2S1	7803
ARFGAP2	7785
TBC1D15	7762
MVB12B	7759
TRAPPC6B	7722
CLTC	7714
PIP5K1C	7704
PRKAB2	7695
DCTN4	7680
MADD	7658
RAB6A	7657
DCTN6	7640
ACTR10	7623
TSG101	7622
PAFAH1B3	7591
STX18	7567
SEC22C	7549
COPS8	7530
VPS53	7504
RPS27A	7499
STX5	7498
SNX2	7465
BICD2	7411
TRIP10	7408
COPZ1	7384
IGF2R	7357
SPTB	7355
RAB35	7314
KIFC1	7312
RAB8B	7262
DCTN1	7179
RAB30	7170
NAA30	7087
RAB5A	7043
RAB36	7013
SNF8	7007
RIN1	6983
TRAPPC8	6954
DENND6B	6940
CUX1	6898
KIF18A	6886
COPS5	6872
RABEP1	6846
TFG	6723
RIN3	6545
HSPA8	6500
SPTBN1	6494
FNBP1	6492
TMED3	6451
TSC2	6400
TRAPPC12	6391
GOSR1	6364
ACTR1A	6363
VPS52	6343
RAB12	6331
STAM2	6329
GORASP1	6304
DENND1A	6282
VPS45	6241
GGA1	6236
COG7	6228
TBC1D17	6190
RALGAPB	6158
TRAPPC5	6156
DENND4B	6133
ACTB	6053
PACSIN2	6010
YWHAQ	5997
VAMP3	5877
VPS37D	5847
AP1M1	5820
ARFIP2	5817
PPP6R1	5804
VPS4A	5772
AP2A1	5736
CENPE	5720
SEC31A	5671
GCC1	5602
TOR1A	5587
TBC1D10B	5580
GRK2	5578
CD3G	5500
HIP1	5468
UBC	5385
PRKAG2	5343
AP4S1	5340
TRAPPC9	5310
EXOC5	5304
VPS37A	5285
AP1G2	5284
HBEGF	5232
GALNT2	5186
DYNC1LI1	5132
RGP1	5093
CHMP7	5074
ITSN2	5029
TRAPPC6A	5006
KIF11	4974
EXOC8	4947
AP4E1	4930
ARCN1	4887
NAPG	4880
AP4M1	4864
DENND4A	4861
CNIH1	4855
SEC13	4854
PLA2G6	4834
COPS7B	4815
CTSC	4814
SAR1B	4809
C2CD5	4799
TSC1	4794
ALS2CL	4775
VPS36	4766
RAB5B	4756
KIF5B	4750
SYNJ1	4728
SNX9	4712
KIF20B	4684
COPB2	4677
VPS51	4649
DTNBP1	4607
DCTN5	4586
GJB6	4562
PPP6R3	4532
UBAP1	4463
TRAPPC2L	4448
NECAP2	4429
AVP	4415
ARF3	4380
ULK1	4377
GABARAP	4367
CHMP6	4359
KIF21B	4348
AP2B1	4341
KIF2A	4282
STX17	4251
KIF2B	4249
TUBA4A	4239
TRAPPC13	4211
ARF4	4207
DYNLL1	4203
SCARB2	4179
GOLGA4	4145
STX4	4140
TUBB2A	4122
KLC3	4121
GBF1	4003
RABGAP1	3940
MAN1C1	3933
TUBB2B	3907
COPS4	3879
YWHAH	3875
WASL	3866
MON1A	3835
TUBA4B	3811
SEC24D	3773
CHMP3	3762
CNIH2	3746
COG5	3742
TRAPPC1	3735
EXOC6	3725
BNIP1	3713
SLC2A4	3711
TBC1D16	3621
KDELR2	3617
KIFAP3	3614
BET1L	3531
RINT1	3518
VTI1A	3493
RAB38	3489
RAB10	3401
GJA10	3396
GOLGB1	3374
RIC1	3346
RACGAP1	3319
AP1S3	3259
SPTAN1	3255
KIF20A	3253
DCTN2	3135
AP4B1	3133
UBQLN1	3117
KIF1C	3095
CAPZA1	3088
SEC24A	3029
BET1	2998
NEDD8	2985
NECAP1	2943
COPG2	2885
AP3B1	2798
GCC2	2695
KIF25	2613
GABARAPL2	2594
TBC1D7	2588
PRKAG1	2584
NAA35	2566
COPZ2	2539
STX6	2497
SYTL1	2448
VTA1	2396
TUBB4B	2340
SLC2A8	2308
KIFC2	2288
GALNT1	2285
ARPC5	2177
KIF3B	2165
ARFGAP3	2160
SPTA1	2136
KIF15	2133
NAPB	2126
TPD52	2101
AGFG1	2043
KIF21A	2032
RAB18	2005
DENND1B	1998
EXOC4	1981
NAA38	1949
DENND4C	1948
EXOC2	1943
RAB14	1930
COG4	1895
PIK3C2A	1881
LNPEP	1841
ARF1	1827
GAPVD1	1816
FCHO2	1802
RAB1A	1737
ACTR2	1697
RAB27B	1685
SPTBN2	1662
ARPC1A	1646
GNS	1628
CLTCL1	1596
AREG	1585
MAP1LC3B	1577
STON1	1557
COPS7A	1551
DVL2	1535
BLOC1S4	1531
HIP1R	1528
MIA2	1491
CLTA	1420
KIF26A	1404
GJC2	1374
FCHO1	1368
GDI2	1275
BLOC1S1	1235
COG8	1233
MYO5A	1219
LRP2	1207
YWHAZ	1179
DNM1	1081
ARRB1	1053
KIF23	1051
RAB11A	1050
TBC1D20	1039
TUBA1A	1018
SYS1	990
ARF5	944
TFRC	939
AP1S1	908
GJD4	906
GJA5	826
GJD2	810
GJB4	778
STX16	769
RAB43	757
STAM	744
CAPZA2	668
GJA8	658
RAB1B	655
GOLGA5	643
TGFA	600
AKT3	516
TMED7	460
MVB12A	451
EGF	419
BICD1	400
DENND2B	372
TMF1	322
TMED9	318
TF	313
ANK1	268
ADRB2	250
APP	210
COG3	179
YWHAB	170
ANKRD27	160
TUBB6	150
USO1	135
MAN1A2	107
CYTH3	68
MIA3	25
SEC16B	-47
RAB4A	-161
ALS2	-227
BTC	-239
ANK3	-265
USP6NL	-307
TUBB4A	-357
TUBA8	-372
KIF27	-382
RAB31	-484
RAB3GAP2	-572
FTH1	-671
CYTH4	-717
SEC23A	-814
SNX18	-970
MCFD2	-997
SNX5	-1006
KIF2C	-1021
AP1G1	-1050
TRIP11	-1118
LMAN2L	-1131
DENND5A	-1135
KIF1B	-1137
LMAN1	-1248
AP3S1	-1337
TMED2	-1538
SPTBN4	-1563
SNAP29	-1579
RAB27A	-1620
COG6	-1671
TGOLN2	-1672
FTL	-1737
DAB2	-1764
LDLR	-1775
REPS1	-1933
RHOQ	-2003
COPB1	-2012
TACR1	-2077
KIF4B	-2093
GJA3	-2129
SPTBN5	-2148
NSF	-2180
COPS3	-2205
SCFD1	-2211
ACTR3	-2226
UBA52	-2237
GOLIM4	-2296
RAB3A	-2300
CNIH3	-2326
UBB	-2335
VPS54	-2361
BIN1	-2375
SYT2	-2401
BLOC1S3	-2408
KIF26B	-2428
KIF16B	-2475
ZW10	-2497
ACTG1	-2553
PICALM	-2599
RAB6B	-2649
CHMP5	-2668
GJC1	-2689
WNT5A	-2742
MAN1A1	-2748
DYNC1I2	-2797
TRAPPC4	-2867
VAMP8	-2887
KIF6	-2906
SCOC	-3050
STON2	-3071
KIF19	-3093
STXBP3	-3159
RAB33B	-3195
EXOC1	-3376
RHOBTB3	-3378
TUBA3D	-3545
TUBA1C	-3556
PAFAH1B2	-3681
TRAPPC3	-3723
CHRM2	-3734
RAB3IL1	-3746
SYT9	-3764
SNAPIN	-3767
KIF5A	-3770
RALA	-3776
EPS15	-3782
TUBB3	-4002
CD4	-4035
SGIP1	-4154
GJB7	-4182
DENND2C	-4191
RAB32	-4269
DENND5B	-4359
RAB13	-4435
COG2	-4446
SYT1	-4532
TUBA3E	-4662
COL7A1	-4672
ITSN1	-4678
GJB2	-4724
FNBP1L	-4751
TPD52L1	-4864
KIF9	-4865
MYO6	-4877
ANK2	-4910
PRKAA2	-4922
SBF2	-4954
VAMP4	-4957
DNM3	-4963
TBC1D4	-4971
DNAJC6	-5128
EREG	-5213
GOSR2	-5270
DYNC1I1	-5334
KIF3A	-5617
RABEPK	-5652
PRKAG3	-5700
AMPH	-5764
OPTN	-5780
PACSIN1	-5782
PACSIN3	-5812
FZD4	-5821
KIF3C	-5979
SH3GL2	-5994
GRIA1	-6007
CLVS2	-6014
CLVS1	-6023
F5	-6033
GRK3	-6050
VPS25	-6097
TJP1	-6230
KIAA0319	-6262
TUBA1B	-6340
INS	-6353
SH3D19	-6358
SORT1	-6395
TUBB1	-6519
GPS1	-6560
RALGAPA2	-6579
EGFR	-6730
ACBD3	-6735
CHMP4C	-6820
VAMP2	-6867
ARF6	-6897
LMAN1L	-6902
KDELR1	-6907
RAB39A	-6941
RIN2	-7051
FOLR1	-7106
GJA1	-7142
SLC18A3	-7169
SERPINA1	-7239
SNAP23	-7253
TUBA3C	-7269
TUBAL3	-7278
GJA4	-7378
GJD3	-7473
AGTR1	-7523
SNAP91	-7607
KIF1A	-7805
SH3GL3	-7913
ANKRD28	-7958
APOB	-8243
SYT8	-8276
CFTR	-8343
DENND2A	-8445
SFN	-8574
PLA2G4A	-8588
CAPZA3	-8836
TUBB8	-8942
ALPP	-8998
KIF12	-9043
GJB5	-9371

---

REACTOME_SEPARATION_OF_SISTER_CHROMATIDS

REACTOME_SEPARATION_OF_SISTER_CHROMATIDS

	492
set	REACTOME_SEPARATION_OF_SISTER_CHROMATIDS
setSize	184
pANOVA	8.97e-11
s.dist	0.277
p.adjustANOVA	5.66e-09

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RANGAP1	11517
RCC2	11484
INCENP	11431
DYNLL2	11413
ESPL1	11271
PSMB4	11076
PPP2R1B	10998
PSMD4	10893
PSMD13	10870
PPP2R5D	10733
AHCTF1	10728
PSMA2	10707
DYNC1H1	10679
CDC23	10475
ANAPC15	10466
CENPN	10448
PSMC6	10418
PAFAH1B1	10395
CDCA8	10170
DYNC1LI2	10120

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RANGAP1	11517
RCC2	11484
INCENP	11431
DYNLL2	11413
ESPL1	11271
PSMB4	11076
PPP2R1B	10998
PSMD4	10893
PSMD13	10870
PPP2R5D	10733
AHCTF1	10728
PSMA2	10707
DYNC1H1	10679
CDC23	10475
ANAPC15	10466
CENPN	10448
PSMC6	10418
PAFAH1B1	10395
CDCA8	10170
DYNC1LI2	10120
SGO1	10062
NUP85	10023
CENPF	10012
PSMD3	9979
PSMD7	9804
PSMC4	9692
NSL1	9660
ANAPC1	9651
PSMD2	9598
CENPS	9547
PSMB5	9461
BUB1B	9388
NUP133	9347
NUDC	9330
CLASP1	9232
PSMF1	9002
CENPP	9001
ZWILCH	8932
XPO1	8891
STAG1	8828
NDEL1	8779
PSMB7	8555
PSMA4	8487
CLIP1	8310
SMC3	8217
PMF1	8197
CDCA5	8184
CKAP5	8128
ANAPC16	8064
PSMB1	7978
PSMA6	7971
NUP98	7826
KNTC1	7772
PSME2	7675
ANAPC4	7652
PSMD1	7564
ANAPC5	7558
RPS27A	7499
PSME1	7470
CDC27	7198
PSMA3	7039
MAD1L1	7020
PSMA1	6977
PSMD6	6942
DSN1	6888
KIF18A	6886
CDC16	6748
NUP37	6708
PSMB3	6665
PSMD11	6649
RPS27	6477
PDS5A	6446
PSMD12	6422
PSMB6	6370
ANAPC10	6338
NUP160	6322
NDE1	6318
PSMD5	6295
PSME3	6289
CENPM	6069
CENPL	6013
PSMD9	5939
ANAPC11	5794
SEH1L	5744
CENPE	5720
CDC26	5692
CENPC	5654
CENPU	5624
PSMB2	5390
UBC	5385
CENPK	5296
DYNC1LI1	5132
CENPQ	5131
PSMA7	5054
PPP2R5C	5016
CLASP2	4967
RANBP2	4890
SEC13	4854
WAPL	4638
B9D2	4467
PSMA8	4378
PPP2R1A	4310
KIF2A	4282
SGO2	4264
KIF2B	4249
TUBA4A	4239
DYNLL1	4203
TUBB2A	4122
PSMC2	4047
PSMB10	3971
BUB3	3920
TUBB2B	3907
BUB1	3874
TUBA4B	3811
CENPO	3792
ANAPC7	3782
ZWINT	3720
TAOK1	3609
PLK1	3472
UBE2E1	3470
PSMC3	3323
NUP107	3276
PSMC1	3148
PSME4	3137
PSMC5	3065
MIS12	2770
TUBB4B	2340
PPP1CC	2315
PSMB8	2300
KNL1	2176
PSMD14	1903
UBE2S	1865
PSMB11	1723
PPP2R5A	1572
SKA2	1570
NDC80	1352
TUBA1A	1018
NUF2	899
AURKB	823
CDC20	611
PDS5B	610
NUP43	561
PPP2CB	497
PPP2R5B	256
TUBB6	150
PPP2R5E	-53
MAPRE1	-157
TUBB4A	-357
TUBA8	-372
KIF2C	-1021
ANAPC2	-1206
CENPA	-1250
UBE2D1	-1471
ITGB3BP	-1974
CENPT	-2031
PTTG1	-2060
PPP2CA	-2084
UBA52	-2237
UBB	-2335
MAD2L1	-2478
ZW10	-2497
CENPH	-2615
DYNC1I2	-2797
PSMB9	-2938
RAD21	-3318
TUBA3D	-3545
TUBA1C	-3556
UBE2C	-3845
TUBB3	-4002
SPC25	-4088
PSMA5	-4331
SKA1	-4482
BIRC5	-4539
TUBA3E	-4662
PSMD8	-5050
DYNC1I1	-5334
SPDL1	-5533
TUBA1B	-6340
TUBB1	-6519
TUBA3C	-7269
TUBAL3	-7278
SEM1	-7461
SPC24	-7608
TUBB8	-8942

---

REACTOME_S_PHASE

REACTOME_S_PHASE

	1110
set	REACTOME_S_PHASE
setSize	159
pANOVA	1.02e-10
s.dist	0.297
p.adjustANOVA	6.04e-09

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TFDP1	11506
FZR1	11268
ORC1	11169
PSMB4	11076
PSMD4	10893
PSMD13	10870
POLD4	10789
MCM7	10739
PSMA2	10707
POLD1	10687
RPA1	10676
CDC25B	10580
CDC23	10475
ANAPC15	10466
PSMC6	10418
E2F4	10203
PSMD3	9979
PSMD7	9804
AKT1	9802
PSMC4	9692

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TFDP1	11506
FZR1	11268
ORC1	11169
PSMB4	11076
PSMD4	10893
PSMD13	10870
POLD4	10789
MCM7	10739
PSMA2	10707
POLD1	10687
RPA1	10676
CDC25B	10580
CDC23	10475
ANAPC15	10466
PSMC6	10418
E2F4	10203
PSMD3	9979
PSMD7	9804
AKT1	9802
PSMC4	9692
ANAPC1	9651
MCM2	9629
PSMD2	9598
PSMB5	9461
CDKN1B	9381
POLD2	9355
PSMF1	9002
POLE	8933
MAX	8923
STAG1	8828
TFDP2	8744
POLA2	8682
PSMB7	8555
LIG1	8548
PSMA4	8487
CCNH	8458
RFC2	8432
AKT2	8422
RBL2	8353
SMC3	8217
CDCA5	8184
ANAPC16	8064
PSMB1	7978
PSMA6	7971
DNA2	7894
CDC45	7713
PSME2	7675
ANAPC4	7652
PSMD1	7564
ANAPC5	7558
RPS27A	7499
PSME1	7470
MCM8	7433
CDC27	7198
CKS1B	7134
PSMA3	7039
PSMA1	6977
PSMD6	6942
CDC16	6748
PSMB3	6665
PSMD11	6649
FEN1	6610
PDS5A	6446
PSMD12	6422
PRIM2	6418
PSMB6	6370
ANAPC10	6338
PSMD5	6295
PSME3	6289
MCM4	6281
MYC	6135
CDK7	6114
PSMD9	5939
GSK3B	5797
ANAPC11	5794
ORC5	5764
CDC26	5692
ORC6	5505
CDC6	5426
PSMB2	5390
UBC	5385
RPA2	5194
ORC3	5191
RFC5	5072
PSMA7	5054
WAPL	4638
RFC4	4504
PSMA8	4378
MCM5	4177
PSMC2	4047
CUL1	4015
PSMB10	3971
MCM3	3886
RBBP4	3878
ANAPC7	3782
SKP1	3705
LIN52	3662
UBE2E1	3470
LIN54	3409
POLE3	3344
ORC4	3333
PSMC3	3323
PSMC1	3148
RPA3	3146
PSME4	3137
GINS2	3128
PSMC5	3065
LIN37	3058
GINS3	2975
RFC3	2692
ESCO2	2436
CDKN1A	2387
PSMB8	2300
GINS1	2279
CDK4	2268
GMNN	2115
PSMD14	1903
UBE2S	1865
PSMB11	1723
RB1	1359
CDC25A	1124
CABLES1	824
POLE2	695
PDS5B	610
PCNA	570
AKT3	516
PRIM1	283
RFC1	4
E2F5	-8
MNAT1	-336
LIN9	-393
GINS4	-690
WEE1	-761
SKP2	-864
ANAPC2	-1206
UBE2D1	-1471
CCND1	-1519
POLD3	-1564
CDT1	-1582
RBX1	-2227
UBA52	-2237
ORC2	-2295
CDK2	-2309
UBB	-2335
POLE4	-2612
PSMB9	-2938
CCNE1	-2947
PTK6	-3078
MCM6	-3207
RAD21	-3318
CCNE2	-3373
UBE2C	-3845
CCNA1	-4120
PSMA5	-4331
ESCO1	-4826
PSMD8	-5050
CCNA2	-5945
SEM1	-7461
E2F1	-8231

---

REACTOME_RHO_GTPASE_EFFECTORS

REACTOME_RHO_GTPASE_EFFECTORS

	342
set	REACTOME_RHO_GTPASE_EFFECTORS
setSize	305
pANOVA	1.03e-10
s.dist	0.215
p.adjustANOVA	6.04e-09

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RAC2	11935
PDPK1	11829
EVL	11654
MYH9	11645
H2BC15	11524
RANGAP1	11517
SRGAP2	11492
RCC2	11484
PKN3	11473
H4C5	11447
INCENP	11431
DYNLL2	11413
H2BC6	11322
DVL1	11215
PPP2R1B	10998
H2AZ1	10867
ROPN1	10736
PPP2R5D	10733
AHCTF1	10728
DYNC1H1	10679

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RAC2	11935.0
PDPK1	11829.0
EVL	11654.0
MYH9	11645.0
H2BC15	11524.0
RANGAP1	11517.0
SRGAP2	11492.0
RCC2	11484.0
PKN3	11473.0
H4C5	11447.0
INCENP	11431.0
DYNLL2	11413.0
H2BC6	11322.0
DVL1	11215.0
PPP2R1B	10998.0
H2AZ1	10867.0
ROPN1	10736.0
PPP2R5D	10733.0
AHCTF1	10728.0
DYNC1H1	10679.0
YWHAE	10677.0
CENPN	10448.0
PAFAH1B1	10395.0
PAK2	10228.0
CDCA8	10170.0
DYNC1LI2	10120.0
SGO1	10062.0
NUP85	10023.0
CENPF	10012.0
IQGAP3	10004.0
CYFIP2	10003.0
DVL3	9939.0
CDC25C	9899.0
DIAPH1	9834.0
KLC1	9809.0
NSL1	9660.0
SRC	9630.0
MRTFA	9588.0
YWHAG	9563.0
CENPS	9547.0
CTTN	9493.0
H2AC4	9477.0
RAC1	9456.0
BUB1B	9388.0
CDKN1B	9381.0
NUP133	9347.0
NCKAP1L	9332.0
NUDC	9330.0
ARPC3	9321.0
PRKCD	9271.0
CLASP1	9232.0
FMNL1	9126.0
CALM1	9105.0
KLC4	9104.0
H4C6	9077.0
CENPP	9001.0
NCKIPSD	8987.0
GRB2	8934.0
ZWILCH	8932.0
H3C11	8908.0
H2BC10	8901.0
XPO1	8891.0
NDEL1	8779.0
ARPC2	8695.0
ARPC4	8481.0
FMNL3	8457.0
KLC2	8445.0
ABI1	8363.0
CLIP1	8310.0
PPP1R12B	8283.0
H2AC6	8277.0
H4C11	8241.0
PMF1	8197.0
CKAP5	8128.0
H4C13	8117.0
KDM1A	8061.0
H4C1	8017.0
NUP98	7826.0
WIPF2	7821.0
RTKN	7818.0
KNTC1	7772.0
RHOC	7731.0
H2AC8	7728.0
CYBA	7724.0
PIN1	7723.0
H2BC4	7539.0
MAPK3	7526.0
H3C1	7395.0
MYH11	7392.0
H2BC9	7228.5
H3C7	7228.5
H4C8	7058.0
MAD1L1	7020.0
MYH10	6987.0
LIMK2	6937.0
KTN1	6901.0
DSN1	6888.0
KIF18A	6886.0
KDM4C	6867.0
PPP1R14A	6799.0
PRKCB	6744.0
NUP37	6708.0
H3C10	6652.0
MYL12B	6608.0
CDC42	6603.0
WASF2	6601.0
RPS27	6477.0
H2BC8	6334.0
NUP160	6322.0
NDE1	6318.0
H2BC12	6220.0
ABL1	6174.0
ARPC1B	6122.0
CYFIP1	6113.0
PPP1R12A	6096.0
CENPM	6069.0
ACTB	6053.0
CENPL	6013.0
YWHAQ	5997.0
H3C4	5911.0
PRKCA	5835.0
MAPK1	5826.0
KIF14	5793.0
SEH1L	5744.0
CENPE	5720.0
CENPC	5654.0
CENPU	5624.0
IQGAP2	5610.0
LIN7B	5512.0
H4C3	5297.0
CENPK	5296.0
CIT	5229.0
MAPK14	5180.0
H2AJ	5141.0
DYNC1LI1	5132.0
CENPQ	5131.0
PPP2R5C	5016.0
CLASP2	4967.0
TAX1BP3	4936.0
RANBP2	4890.0
SEC13	4854.0
S100A9	4820.0
KIF5B	4750.0
RHPN1	4687.0
B9D2	4467.0
PPP2R1A	4310.0
KIF2A	4282.0
SGO2	4264.0
KIF2B	4249.0
TUBA4A	4239.0
DYNLL1	4203.0
TUBB2A	4122.0
KLC3	4121.0
H4C2	3987.0
BUB3	3920.0
TUBB2B	3907.0
YWHAH	3875.0
BUB1	3874.0
WASL	3866.0
TUBA4B	3811.0
CENPO	3792.0
WASF1	3787.0
ZWINT	3720.0
DIAPH3	3654.0
TAOK1	3609.0
H4C4	3596.0
H3C8	3521.0
PIK3C3	3509.0
PKN2	3479.0
PLK1	3472.0
H2AC20	3382.0
ITGB1	3314.0
NUP107	3276.0
PFN2	3247.0
H3-3B	3055.0
PRKCZ	3037.0
RHOA	3000.0
H2AC18	2954.5
H2AC19	2954.5
H2AC7	2792.5
H2BC7	2792.5
BAIAP2	2775.0
MIS12	2770.0
NCF2	2756.0
NCOA2	2754.0
H2BC21	2718.0
WIPF1	2711.0
NF2	2647.0
ROCK2	2635.0
NCF4	2618.0
DAAM1	2586.0
SRF	2415.0
TUBB4B	2340.0
PPP1CC	2315.0
H3-3A	2262.0
CTNNB1	2250.0
ARPC5	2177.0
KNL1	2176.0
H2BC5	2100.0
NCK1	2028.0
MYL6	1979.0
PPP1CB	1887.0
H2BC17	1857.0
H2BC13	1834.0
H3C2	1828.0
ACTR2	1697.0
CFL1	1670.0
ARPC1A	1646.0
PPP2R5A	1572.0
SKA2	1570.0
DVL2	1535.0
NDC80	1352.0
H2BC11	1286.0
KLK2	1249.0
YWHAZ	1179.0
TUBA1A	1018.0
NUF2	899.0
AURKB	823.0
CDC20	611.0
NUP43	561.0
PPP2CB	497.0
NCKAP1	438.0
PPP2R5B	256.0
MEN1	220.0
YWHAB	170.0
TUBB6	150.0
PFN1	92.0
PPP2R5E	-53.0
MYH14	-86.0
ROCK1	-121.0
DLG4	-148.0
MAPRE1	-157.0
PKN1	-168.0
H4C9	-276.0
CTNNA1	-328.0
TUBB4A	-357.0
TUBA8	-372.0
H2AX	-614.0
LIMK1	-688.0
MYL9	-693.0
KIF2C	-1021.0
ABI2	-1037.0
PTK2	-1164.0
CENPA	-1250.0
PRC1	-1291.0
IQGAP1	-1341.0
ITGB3BP	-1974.0
RHOQ	-2003.0
CENPT	-2031.0
PPP2CA	-2084.0
ACTR3	-2226.0
CDH1	-2234.0
NOXO1	-2306.0
MAD2L1	-2478.0
ZW10	-2497.0
ACTG1	-2553.0
CENPH	-2615.0
NOX3	-2633.0
PAK1	-2725.0
KLK3	-2788.0
DYNC1I2	-2797.0
H2BC26	-2895.0
PIK3R4	-2946.0
SCAI	-3269.0
TUBA3D	-3545.0
TUBA1C	-3556.0
KIF5A	-3770.0
H2AZ2	-3800.0
MAPK11	-3828.0
RHOG	-3953.0
TUBB3	-4002.0
SPC25	-4088.0
RHOB	-4209.0
RHOD	-4433.0
H2BC1	-4453.0
SKA1	-4482.0
BIRC5	-4539.0
TUBA3E	-4662.0
H3C6	-4925.0
NOXA1	-4995.0
DYNC1I1	-5334.0
H2AC14	-5418.0
SPDL1	-5533.0
H2BC3	-5733.0
H4C16	-5871.0
BRK1	-5954.0
S100A8	-5997.0
MYLK	-6020.0
FMNL2	-6188.0
WASF3	-6206.0
TUBA1B	-6340.0
TUBB1	-6519.0
GOPC	-6556.0
RHPN2	-6573.0
H3C3	-6688.0
H2BC14	-7035.0
H4C12	-7199.0
TUBA3C	-7269.0
TUBAL3	-7278.0
SPC24	-7608.0
H3C12	-7844.0
CFTR	-8343.0
SFN	-8574.0
TUBB8	-8942.0
WIPF3	-9061.0

---

REACTOME_GPCR_LIGAND_BINDING

REACTOME_GPCR_LIGAND_BINDING

	834
set	REACTOME_GPCR_LIGAND_BINDING
setSize	444
pANOVA	1.1e-10
s.dist	-0.179
p.adjustANOVA	6.11e-09

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CCL11	-9659
FSHB	-9632
DRD5	-9602
NTS	-9484
NMUR2	-9478
CXCL9	-9451
TAS2R46	-9441
HCAR1	-9370
TAS2R16	-9282
CXCL5	-9233
GHRHR	-9137
CCR5	-9073
FPR2	-9018
CCL7	-9017
TAS2R42	-8987
CCL25	-8926
LHCGR	-8891
ACKR2	-8853
TRHR	-8813
PPBP	-8757

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CCL11	-9659
FSHB	-9632
DRD5	-9602
NTS	-9484
NMUR2	-9478
CXCL9	-9451
TAS2R46	-9441
HCAR1	-9370
TAS2R16	-9282
CXCL5	-9233
GHRHR	-9137
CCR5	-9073
FPR2	-9018
CCL7	-9017
TAS2R42	-8987
CCL25	-8926
LHCGR	-8891
ACKR2	-8853
TRHR	-8813
PPBP	-8757
PRLH	-8756
NPY5R	-8754
HTR2A	-8723
TAC3	-8635
GIP	-8631
FFAR4	-8627
CXCL2	-8531
TAS2R40	-8456
MLN	-8455
PROKR2	-8346
CRHBP	-8334
RAMP3	-8294
CALCR	-8269
GLP1R	-8241
PYY	-8223
RHO	-8208
CXCL8	-8180
CXCL6	-8179
GNG8	-8059
HTR4	-8038
CRHR1	-8008
GNRHR	-7976
PTH	-7881
NPY2R	-7874
IHH	-7870
MC2R	-7851
PLPPR2	-7832
GRM2	-7813
ADRA1D	-7766
GRM3	-7720
TAAR1	-7718
CXCL3	-7716
HCAR2	-7715
CALCRL	-7704
GAL	-7702
GRM5	-7657
HRH1	-7627
RGR	-7587
AGTR1	-7523
CCL21	-7520
MC3R	-7518
NPFFR2	-7482
PLPPR5	-7437
LPAR1	-7394
XCL1	-7367
S1PR3	-7357
GRM4	-7350
SST	-7285
BDKRB1	-7242
CCL5	-7234
UTS2B	-7185
OXGR1	-7181
GCG	-7146
WNT16	-7139
GRM7	-7131
AVPR1A	-7128
GPR39	-7091
CXCL12	-7055
NPFFR1	-7021
GHSR	-7002
GRM1	-6953
HCRTR1	-6916
TAS2R38	-6813
GNRH2	-6737
HRH2	-6716
NPB	-6697
DRD3	-6622
UTS2	-6613
HTR1E	-6598
PTH1R	-6595
CMKLR1	-6561
P2RY1	-6554
RLN2	-6423
EDNRA	-6394
SCTR	-6386
OPRK1	-6371
GPHA2	-6366
DRD2	-6342
C5	-6178
WNT2	-6162
QRFPR	-6154
PDYN	-6132
EDN2	-6131
PTCH2	-6038
NPBWR2	-5977
CALCB	-5940
OPRL1	-5895
GPR68	-5878
HTR1B	-5865
CCRL2	-5848
FZD4	-5821
GPR31	-5814
ADRA1A	-5789
TACR3	-5769
EDN3	-5762
VIPR2	-5729
HTR7	-5692
CHRM5	-5689
CXCL1	-5649
CCL20	-5645
TSHR	-5631
PRLHR	-5587
SUCNR1	-5570
WNT10B	-5551
NPSR1	-5546
PROK1	-5515
GPR55	-5477
TAS2R19	-5472
PLPPR1	-5449
TAC1	-5446
DHH	-5378
NTSR2	-5365
QRFP	-5325
CCL28	-5297
PTGER3	-5273
SMO	-5257
GABBR2	-5243
TAS2R50	-5193
MCHR2	-5169
ANXA1	-5156
ADRA2C	-5100
C3	-5027
GPR37	-5016
CRHR2	-4945
PTH2	-4903
UTS2R	-4862
CRH	-4840
NMS	-4837
PTGFR	-4797
FSHR	-4766
NMU	-4758
NPBWR1	-4695
CCR2	-4605
HTR1A	-4589
HRH3	-4563
ADRA2A	-4367
GALR3	-4287
ADGRE1	-4190
CNR1	-4177
WNT9A	-4105
GPRC6A	-4100
WNT3A	-4055
VIP	-4040
FZD7	-4037
ADCYAP1R1	-4014
GRM8	-3996
KNG1	-3949
DRD4	-3895
GLP2R	-3882
TSHB	-3854
TAS2R1	-3790
KEL	-3771
CHRM1	-3754
UCN3	-3753
CHRM2	-3734
CHRM4	-3651
GPR65	-3645
FFAR2	-3640
KISS1R	-3576
CCL27	-3573
NMBR	-3568
GPHB5	-3538
WNT7B	-3533
S1PR2	-3528
SSTR2	-3526
CCL17	-3513
CCL16	-3451
MTNR1B	-3391
RRH	-3340
TAS2R31	-3272
PTHLH	-3268
MTNR1A	-3166
P2RY13	-3121
MC5R	-3068
TAS1R1	-3055
F2RL1	-2950
RXFP3	-2914
ADORA1	-2876
GNG12	-2840
RXFP2	-2831
XCL2	-2804
WNT5A	-2742
CORT	-2718
GPR37L1	-2700
F2RL3	-2678
CHRM3	-2662
FZD6	-2656
TAAR9	-2629
WNT7A	-2561
EDN1	-2525
GNG13	-2505
WNT6	-2485
VIPR1	-2457
FFAR1	-2331
CX3CL1	-2318
HRH4	-2270
GRM6	-2176
ADRA2B	-2091
NPW	-2085
TACR1	-2077
CALCA	-2049
APLNR	-2033
AVPR1B	-1988
CXCL16	-1935
PLPPR4	-1929
WNT1	-1886
P2RY6	-1846
ADCYAP1	-1782
FZD8	-1730
GIPR	-1514
GPR17	-1483
HTR5A	-1386
CGA	-1355
WNT10A	-1265
S1PR4	-1257
SHH	-1204
HTR6	-1127
FZD5	-1120
NPY	-1082
DRD1	-1074
TAS1R2	-1046
PENK	-1044
CASR	-1032
TAS2R14	-1000
WNT2B	-998
OPN5	-994
CXCL13	-959
ECE2	-935
FZD1	-809
CXCL11	-681
P2RY2	-674
NPY1R	-672
ADM2	-666
MC1R	-665
OPRD1	-639
TRH	-508
GNG4	-501
PTGER4	-463
KISS1	-346
PPY	-327
WNT11	-268
CXCR6	-259
GALR2	-222
CCL3	-216
SSTR4	-182
WNT9B	-170
PTGER1	-123
CNR2	40
BDKRB2	143
APP	210
ADRB2	250
PTCH1	259
HCRTR2	363
CCL2	429
NLN	455
OPRM1	481
F2R	490
CCKBR	601
PTGER2	633
RXFP1	663
UCN2	683
GHRH	697
PMCH	787
SCT	790
CCR10	798
FZD10	809
OPN3	830
PTH2R	859
PROK2	881
CXCR2	972
CCKAR	1108
S1PR5	1129
TAS2R20	1152
CCR8	1213
CYSLTR2	1423
CCR6	1607
CCK	1641
TAAR5	1658
FZD3	1720
C5AR2	1721
NPS	1779
GABBR1	1835
EDNRB	1950
TAS2R8	2018
ACKR3	2030
ADRB1	2090
TAS2R7	2237
P2RY12	2294
TAS2R9	2307
TACR2	2313
SAA1	2365
TAS2R41	2475
NTSR1	2525
HTR1F	2608
ADRA1B	2668
OXT	2673
MLNR	2686
RAMP1	2854
TAS2R5	3112
SSTR3	3119
LPAR3	3183
CCL23	3248
OPN4	3264
GALR1	3318
RAMP2	3432
CXCR4	3682
INSL5	3793
PLPPR3	3894
TAS2R4	3896
TAS2R39	3973
SSTR5	4023
ADGRE3	4092
WNT4	4244
HTR1D	4280
ADRB3	4300
PTGDR	4342
AVP	4415
TBXA2R	4600
POMC	4603
WNT8B	4863
WNT3	4883
GNAS	4912
ADGRE5	4916
GPR4	5049
GNB5	5393
FZD9	5394
GNB4	5421
GPR35	5427
FZD2	5535
FPR3	5595
GNG3	5611
ADM	5683
SSTR1	5812
CX3CR1	5828
HTR2B	5869
GNB2	5886
TAAR6	5982
NMB	6004
P2RY14	6054
GNG2	6075
GNG7	6169
C3AR1	6258
CCL22	6351
GPR18	6536
OXTR	6662
GNRH1	6753
TAS2R60	6794
GNG5	6795
HEBP1	6796
LPAR2	6863
PROKR1	6921
CCL13	6984
TAAR2	7109
CXCL10	7118
MC4R	7143
GRP	7225
GHRL	7238
PSAP	7288
C5AR1	7482
LTB4R2	7573
WNT8A	7609
LTB4R	7663
TAS2R10	7676
ECE1	7690
ACKR4	7965
GPER1	7976
GPR183	8031
CCR1	8097
CCL19	8121
PTAFR	8135
GNGT1	8221
ADGRE2	8239
NPFF	8244
UCN	8249
GPR132	8465
CXCR1	8486
GNG10	8565
PNOC	8711
PF4	8810
GPBAR1	8821
RLN3	8872
CD55	9018
GNG11	9097
F2RL2	9265
LHB	9354
ADORA2B	9373
ACKR1	9409
FPR1	9466
S1PR1	9555
OPN1SW	9578
CCR4	9881
LPAR6	9887
F2	9951
P2RY11	10171
PTGDR2	10194
GNB3	10486
FFAR3	10493
CCL1	10556
CCR3	10713
GNB1	10735
ADORA3	10812
CCR9	10818
GNGT2	10852
AGT	10858
CCR7	10873
IAPP	10925
CXCR5	11062
TAS2R3	11078
XCR1	11160
TAS2R43	11381
ADORA2A	11391
MCHR1	11604
TAS1R3	11617
OXER1	11630
TAS2R30	11710
INSL3	11723
NMUR1	11877
TAS2R13	11892
HCRT	11913
PTGIR	12072
TAAR8	12135
LPAR5	12171
RXFP4	12193
CCL4	12233

---

REACTOME_UCH_PROTEINASES

REACTOME_UCH_PROTEINASES

	1002
set	REACTOME_UCH_PROTEINASES
setSize	99
pANOVA	1.12e-10
s.dist	0.375
p.adjustANOVA	6.11e-09

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MBD6	11516
TGFBR1	11304
TGFB1	11148
FOXK2	11092
PSMB4	11076
PSMD4	10893
PSMD13	10870
KDM1B	10773
PSMA2	10707
H2AC15	10614
YY1	10609
PSMC6	10418
MCRS1	10068
FOXK1	10047
PSMD3	9979
H2AC12	9830
PSMD7	9804
PSMC4	9692
SMAD7	9613
PSMD2	9598

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MBD6	11516.0
TGFBR1	11304.0
TGFB1	11148.0
FOXK2	11092.0
PSMB4	11076.0
PSMD4	10893.0
PSMD13	10870.0
KDM1B	10773.0
PSMA2	10707.0
H2AC15	10614.0
YY1	10609.0
PSMC6	10418.0
MCRS1	10068.0
FOXK1	10047.0
PSMD3	9979.0
H2AC12	9830.0
PSMD7	9804.0
PSMC4	9692.0
SMAD7	9613.0
PSMD2	9598.0
H2AC4	9477.0
PSMB5	9461.0
ACTR8	9367.0
INO80	9340.0
ADRM1	9099.0
PSMF1	9002.0
H2AC11	8737.0
PSMB7	8555.0
PSMA4	8487.0
ACTL6A	8382.0
H2AC6	8277.0
PSMB1	7978.0
PSMA6	7971.0
H2AC8	7728.0
PSME2	7675.0
PSMD1	7564.0
NFRKB	7529.0
RPS27A	7499.0
PSME1	7470.0
PSMA3	7039.0
ASXL2	7034.0
ACTR5	6978.0
PSMA1	6977.0
PSMD6	6942.0
H2AC17	6904.0
H2AC21	6681.0
PSMB3	6665.0
PSMD11	6649.0
PSMD12	6422.0
PSMB6	6370.0
PSMD5	6295.0
PSME3	6289.0
ACTB	6053.0
PSMD9	5939.0
TGFBR2	5792.0
UCHL3	5608.0
H2AC16	5532.0
PSMB2	5390.0
UBC	5385.0
PSMA7	5054.0
INO80E	5030.0
INO80D	4422.0
PSMA8	4378.0
INO80C	4091.0
H2AC13	4085.0
PSMC2	4047.0
PSMB10	3971.0
H2AC20	3382.0
PSMC3	3323.0
PSMC1	3148.0
PSME4	3137.0
PSMC5	3065.0
NEDD8	2985.0
H2AC18	2954.5
H2AC19	2954.5
H2AC7	2792.5
ASXL1	2591.0
USP15	2312.0
PSMB8	2300.0
PSMD14	1903.0
PSMB11	1723.0
MBD5	1639.0
INO80B	1555.0
H2AC25	1333.0
TFPT	1282.0
UCHL5	1122.0
SENP8	-323.0
UCHL1	-774.0
UBA52	-2237.0
UBB	-2335.0
PSMB9	-2938.0
BARD1	-3201.0
BAP1	-3896.0
RUVBL1	-4145.0
H2AC1	-4272.0
PSMA5	-4331.0
PSMD8	-5050.0
H2AC14	-5418.0
SEM1	-7461.0

---

REACTOME_HIV_LIFE_CYCLE

REACTOME_HIV_LIFE_CYCLE

	168
set	REACTOME_HIV_LIFE_CYCLE
setSize	145
pANOVA	1.21e-10
s.dist	0.31
p.adjustANOVA	6.36e-09

Top enriched genes

Top 20 genes

GeneID	Gene Rank
POLR2J	11816
SUPT5H	11758
RANGAP1	11517
POLR2A	11407
POLR2E	11395
RAE1	10890
ERCC3	10866
CHMP4B	10836
GTF2A1	10680
ELOB	10535
NUP210	10455
POLR2B	10306
NUP62	10167
TAF4	10162
NELFCD	10110
NUP85	10023
NUP54	9855
TAF13	9847
NELFB	9731
NUP88	9522

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
POLR2J	11816
SUPT5H	11758
RANGAP1	11517
POLR2A	11407
POLR2E	11395
RAE1	10890
ERCC3	10866
CHMP4B	10836
GTF2A1	10680
ELOB	10535
NUP210	10455
POLR2B	10306
NUP62	10167
TAF4	10162
NELFCD	10110
NUP85	10023
NUP54	9855
TAF13	9847
NELFB	9731
NUP88	9522
PPIA	9515
NUP133	9347
VPS37C	9072
VPS37B	9063
FURIN	8913
CHMP2A	8906
XPO1	8891
BANF1	8827
TCEA1	8796
NELFE	8758
CCNT1	8657
NELFA	8636
GTF2F1	8571
LIG1	8548
NUP93	8494
CCNK	8473
CCNH	8458
POLR2H	8450
VPS4B	8449
CHMP2B	8258
POM121	8233
NUP50	8160
AAAS	8159
NUP58	8140
CHMP4A	8022
VPS28	7949
TAF3	7849
NUP98	7826
MVB12B	7759
TAF2	7715
TSG101	7622
RPS27A	7499
TAF4B	7454
GTF2E1	7447
ELL	7361
NCBP2	7200
NUP37	6708
FEN1	6610
SUPT16H	6552
RNGTT	6547
TPR	6489
TAF1L	6402
NUP160	6322
XRCC5	6243
CDK7	6114
VPS37D	5847
VPS4A	5772
SEH1L	5744
TBP	5601
GTF2H3	5566
ELOA	5436
UBC	5385
NUP42	5371
VPS37A	5285
POLR2I	5214
ERCC2	5135
CHMP7	5074
RAN	5055
POLR2G	4982
RANBP2	4890
SEC13	4854
RCC1	4850
GTF2H1	4840
NUP214	4833
PDCD6IP	4812
TAF7	4746
POLR2F	4630
XRCC4	4468
UBAP1	4463
CHMP6	4359
TAF15	4012
CHMP3	3762
GTF2H5	3727
CXCR4	3682
RNMT	3418
NUP107	3276
POLR2D	3258
NDC1	3079
ELOC	2833
GTF2B	2820
GTF2E2	2708
NUP188	2493
NMT1	2410
VTA1	2396
NUP35	2378
CTDP1	2201
GTF2H4	2092
POM121C	2036
TAF6	1945
TAF12	1849
TAF5	1730
GTF2A2	1343
XRCC6	839
LIG4	829
NUP43	561
MVB12A	451
NUP205	331
NCBP1	-175
TAF9	-183
NEDD4L	-256
MNAT1	-336
SSRP1	-796
NMT2	-806
KPNA1	-925
TAF11	-999
GTF2F2	-1392
POLR2L	-1678
CDK9	-1861
RANBP1	-1938
PSIP1	-1996
UBA52	-2237
UBB	-2335
NUP153	-2541
CHMP5	-2668
NUP155	-3213
POLR2K	-3852
CD4	-4035
CCNT2	-4325
TAF10	-5681
POLR2C	-6018
SUPT4H1	-6345
CHMP4C	-6820
ELOA2	-7031
HMGA1	-7614
CCR5	-9073

---

REACTOME_CELLULAR_RESPONSE_TO_CHEMICAL_STRESS

REACTOME_CELLULAR_RESPONSE_TO_CHEMICAL_STRESS

	1583
set	REACTOME_CELLULAR_RESPONSE_TO_CHEMICAL_STRESS
setSize	188
pANOVA	1.24e-10
s.dist	0.272
p.adjustANOVA	6.36e-09

Top enriched genes

Top 20 genes

GeneID	Gene Rank
P4HB	12090
CREBBP	11715
SOD3	11622
GPX7	11314
IDH1	11194
PSMB4	11076
NCOR2	11049
TKT	10905
GSTP1	10897
PSMD4	10893
ATF4	10878
NPLOC4	10876
PSMD13	10870
PSMA2	10707
HM13	10673
GPX2	10608
NOTCH1	10585
MAFG	10481
COX16	10473
PSMC6	10418

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
P4HB	12090
CREBBP	11715
SOD3	11622
GPX7	11314
IDH1	11194
PSMB4	11076
NCOR2	11049
TKT	10905
GSTP1	10897
PSMD4	10893
ATF4	10878
NPLOC4	10876
PSMD13	10870
PSMA2	10707
HM13	10673
GPX2	10608
NOTCH1	10585
MAFG	10481
COX16	10473
PSMC6	10418
MUL1	10314
NCOR1	10213
MED1	10131
COX6B1	10052
TACO1	10013
PSMD3	9979
PSMD7	9804
AKT1	9802
COX14	9790
COX8A	9775
PSMC4	9692
MAFK	9633
PSMD2	9598
PSMB5	9461
EP300	9390
BTRC	9324
TXN2	9280
PRKCD	9271
NDUFA4	9254
PSMF1	9002
NCOA6	8865
PPARA	8725
COX19	8609
PSMB7	8555
PSMA4	8487
AKT2	8422
TALDO1	8385
CARM1	8334
UFD1	8151
GPX3	8136
PSMB1	7978
PSMA6	7971
AQP8	7898
BLVRA	7834
GSR	7831
CSNK2A1	7758
CYBA	7724
PSME2	7675
PSMD1	7564
RPS27A	7499
PSME1	7470
HMOX1	7469
TXNIP	7462
GCLC	7444
CAT	7326
NUDT2	7284
COX5A	7138
PSMA3	7039
PSMA1	6977
PSMD6	6942
HMOX2	6885
PSMB3	6665
PSMD11	6649
PSMD12	6422
PSMB6	6370
FABP1	6369
COX6C	6367
SURF1	6325
PSMD5	6295
PSME3	6289
MYC	6135
CSNK2A2	5953
PSMD9	5939
GSK3B	5797
SIN3A	5710
ABCC1	5652
PRDX5	5581
CSNK2B	5559
SIN3B	5452
HDAC3	5406
PSMB2	5390
UBC	5385
GCLM	5366
TXNRD2	5164
PSMA7	5054
RXRA	4895
HELZ2	4581
SQSTM1	4520
SLC7A11	4510
DPP3	4384
PSMA8	4378
SRXN1	4153
CYCS	4068
PSMC2	4047
CUL1	4015
PSMB10	3971
BLVRB	3862
SKP1	3705
CHD9	3604
PSMC3	3323
PSMC1	3148
PSME4	3137
COX7A2L	3104
PSMC5	3065
COX4I1	3049
LRPPRC	3047
GPX1	2970
CUL3	2861
BRCA1	2780
NCF2	2756
NCOA2	2754
NCF4	2618
COX11	2459
CDKN1A	2387
COX6A1	2351
PSMB8	2300
PRDX1	2226
PRDX3	2089
TXN	2053
TXNRD1	2049
COX5B	1997
PSMD14	1903
TGS1	1787
SESN1	1738
PSMB11	1723
KEAP1	1708
MAP1LC3B	1577
NCOA1	1280
STAT3	1277
PALB2	1148
VCP	920
NFE2L2	886
NLRP3	615
AKT3	516
UBXN7	254
TBL1XR1	245
CDKN2A	229
HBA2	84
COX7C	-37
TRIM21	-70
ATOX1	-422
FBXL17	-532
ALB	-650
STAP2	-651
SKP2	-864
NOX4	-1026
ERO1A	-1028
SCO1	-1148
PRDX2	-1476
GPX5	-2058
NOX5	-2111
NQO1	-2121
RBX1	-2227
UBA52	-2237
UBB	-2335
GPX6	-2824
PSMB9	-2938
ME1	-3027
PTK6	-3078
SESN2	-3193
COX18	-3348
BACH1	-3711
COX20	-3906
SOD2	-4248
CCS	-4259
SOD1	-4277
PSMA5	-4331
SCO2	-4677
PSMD8	-5050
GPX8	-5264
PRDX6	-5370
SMARCD3	-6048
PGD	-6138
SEM1	-7461
GSTA3	-7569
HBB	-8725
GSTA1	-8741
HBA1	-9321

---

REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION

REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION

	1635
set	REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION
setSize	296
pANOVA	1.35e-10
s.dist	0.217
p.adjustANOVA	6.72e-09

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RNF123	11967
MGRN1	11664
FBXW12	11548
RNF4	11536
UBR4	11519
FBXL14	11460
TRIM41	11433
RNF34	11329
FZR1	11268
UBE2F	11232
HERC3	11087
PSMB4	11076
KLHL42	11033
FBXW10	10958
UBE2V2	10901
PSMD4	10893
PSMD13	10870
PSMA2	10707
RNF41	10691
UBE2R2	10667

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RNF123	11967
MGRN1	11664
FBXW12	11548
RNF4	11536
UBR4	11519
FBXL14	11460
TRIM41	11433
RNF34	11329
FZR1	11268
UBE2F	11232
HERC3	11087
PSMB4	11076
KLHL42	11033
FBXW10	10958
UBE2V2	10901
PSMD4	10893
PSMD13	10870
PSMA2	10707
RNF41	10691
UBE2R2	10667
RNF138	10576
HECTD1	10539
ELOB	10535
CDC23	10475
PSMC6	10418
WWP1	10374
FBXO4	10256
UBE2O	10212
NPEPPS	10198
TRIM39	10193
KLHL22	10192
LRSAM1	10114
FBXW9	9987
PSMD3	9979
FBXO10	9971
TRAF7	9926
ASB1	9894
FBXL18	9869
FBXO7	9868
PSMD7	9804
RNF126	9693
PSMC4	9692
ANAPC1	9651
ASB7	9628
SMURF2	9601
PSMD2	9598
FBXL3	9531
UBE2L3	9504
PSMB5	9461
FBXL22	9441
DET1	9365
BTRC	9324
KBTBD7	9221
HERC2	9108
PSMF1	9002
TPP2	8888
TRIM32	8755
THOP1	8688
PSMB7	8555
UBAC1	8526
PSMA4	8487
SMURF1	8435
LONRF1	8405
DCAF1	8391
UNKL	8356
TRIM11	8322
ASB3	8291
KLHL21	8147
UBE3B	8137
UBE2J1	8049
FBXW11	8014
UBE2J2	7980
PSMB1	7978
PSMA6	7971
ARIH2	7957
AREL1	7943
KLHL20	7870
UBE2M	7791
RNF6	7784
FBXW4	7739
RNF213	7718
PSME2	7675
ANAPC4	7652
PSMD1	7564
ANAPC5	7558
RPS27A	7499
PSME1	7470
MIB2	7445
GLMN	7441
RNF14	7419
UBE2G1	7365
CDC27	7198
BTBD1	7196
UBE2Q1	7177
TRIM4	7175
UBE3C	7105
PSMA3	7039
PSMA1	6977
PSMD6	6942
UBA7	6913
UBE2L6	6911
TRIM37	6818
PJA2	6804
CDC16	6748
HECTD3	6701
PSMB3	6665
CUL7	6650
PSMD11	6649
PSMD12	6422
PSMB6	6370
GAN	6368
ANAPC10	6338
PSMD5	6295
PSME3	6289
SIAH2	6239
MYLIP	6233
ASB13	6227
FBXW8	6055
PSMD9	5939
UBE2B	5859
FBXO31	5838
UBE2H	5833
ANAPC11	5794
ASB6	5724
CDC26	5692
FBXL19	5598
HERC5	5514
UBE2Q2	5502
ATG7	5490
ASB8	5407
PSMB2	5390
UBC	5385
TRIP12	5242
PSMA7	5054
ITCH	5050
KBTBD6	4917
UBR2	4857
UBR1	4731
RNF114	4711
LRRC41	4669
ZNRF2	4598
WSB1	4494
UFL1	4478
FBXW7	4447
HERC4	4439
FBXO9	4405
FBXO21	4404
PSMA8	4378
FBXW2	4290
UBE2D3	4277
HERC6	4247
RNF25	4237
FBXO44	4218
TRIM71	4130
FBXO30	4084
PSMC2	4047
CUL1	4015
PSMB10	3971
CUL5	3961
HERC1	3880
FBXO11	3860
ANAPC13	3819
RNF19A	3796
ANAPC7	3782
RNF220	3778
UBE3D	3722
SKP1	3705
FBXO22	3648
RNF111	3481
UBE2E1	3470
UBE3A	3358
PSMC3	3323
CCNF	3322
PSMC1	3148
PSME4	3137
PSMC5	3065
FBXO32	3005
UBE2E3	2917
UBA5	2907
CUL3	2861
ELOC	2833
KCTD6	2802
RBBP6	2741
SPSB1	2650
UBE4A	2509
RNF130	2371
KCTD7	2358
PSMB8	2300
FBXL16	2155
FBXO6	2038
PSMD14	1903
UBE2S	1865
LNPEP	1841
KLHL2	1748
PSMB11	1723
KEAP1	1708
UBOX5	1565
UBE2D2	1556
KLHL3	1554
KLHL25	1524
DZIP3	1272
RCHY1	1186
KBTBD8	1150
ZBTB16	1109
NEDD4	1072
RBCK1	914
CDC20	611
RNF115	571
KLHL5	426
ASB17	371
RNF19B	332
FBXW5	304
UBE2W	159
TRIM21	-70
RNF7	-73
NEDD4L	-256
DTX3L	-309
UBE2G2	-401
TRIM36	-455
LTN1	-609
TRAIP	-627
MKRN1	-634
VHL	-675
KLHL9	-718
SKP2	-864
RNF144B	-983
HACE1	-1005
SPSB4	-1013
FBXL5	-1073
CUL2	-1184
ANAPC2	-1206
FBXO27	-1351
UBA6	-1362
ZNRF1	-1400
TRIM9	-1412
BLMH	-1433
UBE2D1	-1471
FBXL20	-1584
SOCS1	-1703
FBXL13	-1785
FBXO17	-1911
FBXL15	-2061
FBXO41	-2224
RBX1	-2227
UBA52	-2237
UBB	-2335
UBE2U	-2383
CBLB	-2538
ASB14	-2586
LNX1	-2594
RNF217	-2595
UBA3	-2699
UBE2V1	-2729
PSMB9	-2938
MEX3C	-2960
ASB4	-3092
FBXO15	-3152
SH3RF1	-3153
SIAH1	-3505
FBXO2	-3703
UBE2K	-3824
UBE2C	-3845
ASB15	-3864
CDC34	-3973
ASB10	-3981
ASB18	-4004
TRIM50	-4184
LRR1	-4192
PSMA5	-4331
BTBD6	-4460
UBE2Z	-4518
PRKN	-4525
STUB1	-4920
UBE2E2	-5024
LMO7	-5044
PSMD8	-5050
KLHL11	-5456
FBXL4	-5609
FBXO40	-5727
SPSB2	-5761
HECTD2	-5801
UBE2D4	-5975
FBXL8	-6004
ASB2	-6415
UBE2N	-6864
HECW2	-7443
SEM1	-7461
ASB16	-7542
FBXL7	-7868
FBXL12	-8149
SOCS3	-8205
ASB5	-8319
KLHL41	-8410
RNF182	-8893
TRIM63	-9231
TRIM69	-9354

---

REACTOME_UB_SPECIFIC_PROCESSING_PROTEASES

REACTOME_UB_SPECIFIC_PROCESSING_PROTEASES

	1004
set	REACTOME_UB_SPECIFIC_PROCESSING_PROTEASES
setSize	187
pANOVA	2.05e-10
s.dist	0.269
p.adjustANOVA	9.9e-09

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RNF123	11967
TAB1	11909
AXIN1	11805
WDR20	11739
TADA2B	11706
H2BC15	11524
H2BC6	11322
TGFBR1	11304
USP22	11278
PSMB4	11076
USP5	11026
USP7	10931
PSMD4	10893
PSMD13	10870
USP20	10779
RCE1	10746
PSMA2	10707
ARRB2	10636
H2AC15	10614
PSMC6	10418

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RNF123	11967.0
TAB1	11909.0
AXIN1	11805.0
WDR20	11739.0
TADA2B	11706.0
H2BC15	11524.0
H2BC6	11322.0
TGFBR1	11304.0
USP22	11278.0
PSMB4	11076.0
USP5	11026.0
USP7	10931.0
PSMD4	10893.0
PSMD13	10870.0
USP20	10779.0
RCE1	10746.0
PSMA2	10707.0
ARRB2	10636.0
H2AC15	10614.0
PSMC6	10418.0
MUL1	10314.0
PSMD3	9979.0
RIPK1	9907.0
H2AC12	9830.0
PSMD7	9804.0
USP18	9787.0
PSMC4	9692.0
SMAD7	9613.0
SMURF2	9601.0
PSMD2	9598.0
H2AC4	9477.0
PSMB5	9461.0
TRRAP	9187.0
TADA3	9149.0
ADRM1	9099.0
PSMF1	9002.0
H2BC10	8901.0
H2AC11	8737.0
USP42	8692.0
HGS	8560.0
PSMB7	8555.0
KAT2A	8511.0
PSMA4	8487.0
H2AC6	8277.0
UFD1	8151.0
USP19	8149.0
PSMB1	7978.0
PSMA6	7971.0
TOMM20	7910.0
USP34	7897.0
CYLD	7822.0
TRAF2	7733.0
H2AC8	7728.0
PSME2	7675.0
PSMD1	7564.0
H2BC4	7539.0
RPS27A	7499.0
PSME1	7470.0
USP21	7266.0
H2BC9	7228.5
PSMA3	7039.0
PSMA1	6977.0
PSMD6	6942.0
H2AC17	6904.0
PTRH2	6850.0
USP8	6839.0
SNX3	6782.0
MAT2B	6771.0
ATXN7	6733.0
H2AC21	6681.0
SUDS3	6677.0
PSMB3	6665.0
PSMD11	6649.0
PSMD12	6422.0
PSMB6	6370.0
H2BC8	6334.0
STAM2	6329.0
PSMD5	6295.0
PSME3	6289.0
SIAH2	6239.0
H2BC12	6220.0
MDM4	6157.0
MYC	6135.0
RHOT1	6040.0
USP12	5987.0
PSMD9	5939.0
POLB	5870.0
SMAD2	5768.0
USP13	5634.0
H2AC16	5532.0
PSMB2	5390.0
UBC	5385.0
USP16	5104.0
MDM2	5073.0
PSMA7	5054.0
DDB2	4656.0
USP4	4428.0
PSMA8	4378.0
VDAC3	4338.0
GATA3	4254.0
H2AC13	4085.0
PTEN	4078.0
PSMC2	4047.0
PSMB10	3971.0
RNF146	3594.0
USP3	3574.0
TP53	3499.0
USP47	3460.0
SMAD3	3402.0
H2AC20	3382.0
PSMC3	3323.0
BIRC2	3188.0
PSMC1	3148.0
PSME4	3137.0
PSMC5	3065.0
H2AC18	2954.5
H2AC19	2954.5
H2AC7	2792.5
H2BC7	2792.5
H2BC21	2718.0
MAP3K7	2632.0
USP15	2312.0
PSMB8	2300.0
USP28	2260.0
USP30	2233.0
USP2	2228.0
H2BC5	2100.0
TOMM70	2006.0
PSMD14	1903.0
H2BC17	1857.0
H2BC13	1834.0
CLSPN	1743.0
PSMB11	1723.0
KEAP1	1708.0
TNKS	1634.0
IDE	1444.0
H2AC25	1333.0
USP48	1328.0
H2BC11	1286.0
CDC25A	1124.0
ARRB1	1053.0
USP37	840.0
SMAD1	803.0
CCP110	730.0
WDR48	701.0
USP24	640.0
CDC20	611.0
ADRB2	250.0
BECN1	214.0
TRAF6	213.0
USP33	120.0
USP10	79.0
USP14	-57.0
OTUB1	-534.0
FKBP8	-577.0
VDAC2	-858.0
SKP2	-864.0
USP25	-1706.0
UBA52	-2237.0
IFIH1	-2291.0
NFKBIA	-2315.0
UBB	-2335.0
BIRC3	-2406.0
SMAD4	-2666.0
H2BC26	-2895.0
RIGI	-2937.0
PSMB9	-2938.0
AXIN2	-3173.0
VDAC1	-3516.0
CCNA1	-4120.0
RUVBL1	-4145.0
H2AC1	-4272.0
PSMA5	-4331.0
H2BC1	-4453.0
HIF1A	-4580.0
TNKS2	-4742.0
PSMD8	-5050.0
H2AC14	-5418.0
USP49	-5664.0
TAF10	-5681.0
USP44	-5721.0
H2BC3	-5733.0
CCNA2	-5945.0
H2BC14	-7035.0
SEM1	-7461.0
CFTR	-8343.0
IL33	-9101.0

---

REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

	1585
set	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3
setSize	679
pANOVA	2.72e-10
s.dist	0.142
p.adjustANOVA	1.27e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RAC2	11935
LCK	11904
PDPK1	11829
LETM1	11817
EVL	11654
MYH9	11645
H2BC15	11524
RANGAP1	11517
SRGAP2	11492
RCC2	11484
ARHGEF2	11482
PKN3	11473
H4C5	11447
INCENP	11431
CDC42EP2	11420
CDC37	11416
DYNLL2	11413
C1QBP	11327
H2BC6	11322
ARHGAP9	11300

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RAC2	11935.0
LCK	11904.0
PDPK1	11829.0
LETM1	11817.0
EVL	11654.0
MYH9	11645.0
H2BC15	11524.0
RANGAP1	11517.0
SRGAP2	11492.0
RCC2	11484.0
ARHGEF2	11482.0
PKN3	11473.0
H4C5	11447.0
INCENP	11431.0
CDC42EP2	11420.0
CDC37	11416.0
DYNLL2	11413.0
C1QBP	11327.0
H2BC6	11322.0
ARHGAP9	11300.0
YKT6	11228.0
DVL1	11215.0
ARHGAP45	11015.0
PPP2R1B	10998.0
DDRGK1	10994.0
STK10	10972.0
FGD3	10918.0
H2AZ1	10867.0
SCRIB	10855.0
ARHGDIA	10817.0
GNA13	10791.0
CSK	10782.0
ZAP70	10741.0
ROPN1	10736.0
PPP2R5D	10733.0
AHCTF1	10728.0
DYNC1H1	10679.0
YWHAE	10677.0
TPM3	10638.0
ARHGAP17	10634.0
MYO9B	10547.0
CENPN	10448.0
PAFAH1B1	10395.0
PLIN3	10369.0
ANKRD26	10326.0
MSI2	10288.0
GOLGA3	10241.0
PAK2	10228.0
CDCA8	10170.0
DYNC1LI2	10120.0
ACTN1	10083.0
SGO1	10062.0
NUP85	10023.0
CENPF	10012.0
IQGAP3	10004.0
CYFIP2	10003.0
UBXN11	9983.0
DVL3	9939.0
GFOD1	9924.0
VIM	9918.0
CDC25C	9899.0
WDR11	9895.0
SOS1	9884.0
GIT2	9862.0
DIAPH1	9834.0
KLC1	9809.0
PLD2	9698.0
PAK4	9670.0
MTR	9662.0
NSL1	9660.0
SRC	9630.0
MRTFA	9588.0
LAMTOR1	9581.0
MFN2	9576.0
YWHAG	9563.0
CENPS	9547.0
HNRNPC	9537.0
CTTN	9493.0
H2AC4	9477.0
RAC1	9456.0
CPD	9432.0
NISCH	9427.0
BUB1B	9388.0
CDKN1B	9381.0
NUP133	9347.0
ERBIN	9346.0
NCKAP1L	9332.0
NUDC	9330.0
ARPC3	9321.0
ARHGAP35	9304.0
PRKCD	9271.0
RAB7A	9267.0
FGD2	9236.0
CLASP1	9232.0
FMNL1	9126.0
CALM1	9105.0
KLC4	9104.0
BCR	9095.0
H4C6	9077.0
SRRM1	9051.0
ELMO2	9037.0
CENPP	9001.0
NCKIPSD	8987.0
GRB2	8934.0
ZWILCH	8932.0
H3C11	8908.0
H2BC10	8901.0
WWP2	8894.0
XPO1	8891.0
WDR81	8812.0
ARHGAP19	8781.0
NDEL1	8779.0
ARPC2	8695.0
COPS2	8678.0
FLOT1	8646.0
ARAP1	8641.0
RHOF	8610.0
HGS	8560.0
ALDH3A2	8491.0
ARPC4	8481.0
ESYT1	8462.0
FMNL3	8457.0
KLC2	8445.0
ABI1	8363.0
CLIP1	8310.0
PPP1R12B	8283.0
H2AC6	8277.0
H4C11	8241.0
KCTD13	8203.0
PMF1	8197.0
AAAS	8159.0
PREX1	8146.0
DEF6	8145.0
ANKFY1	8139.0
CKAP5	8128.0
ARHGAP1	8127.0
H4C13	8117.0
KDM1A	8061.0
H4C1	8017.0
RAP1GDS1	8007.0
PIK3R2	7993.0
CAPZB	7951.0
ARHGEF1	7882.0
CDC42EP5	7844.0
ARHGAP30	7827.0
NUP98	7826.0
WIPF2	7821.0
RTKN	7818.0
FLOT2	7786.0
ARFGAP2	7785.0
KNTC1	7772.0
HINT2	7741.0
RHOC	7731.0
H2AC8	7728.0
CYBA	7724.0
PIN1	7723.0
RNF20	7716.0
CLTC	7714.0
TRA2B	7660.0
CCT7	7598.0
PLEKHG1	7575.0
EFHD2	7563.0
H2BC4	7539.0
MAPK3	7526.0
STX5	7498.0
LBR	7494.0
TRIP10	7408.0
TAOK3	7401.0
H3C1	7395.0
MYH11	7392.0
PEAK1	7249.0
H2BC9	7228.5
H3C7	7228.5
ARHGAP23	7209.0
TNFAIP1	7162.0
ARHGAP27	7095.0
GARRE1	7068.0
SPEN	7061.0
H4C8	7058.0
MAD1L1	7020.0
ARHGAP18	7014.0
MYH10	6987.0
LIMK2	6937.0
KTN1	6901.0
DSN1	6888.0
KIF18A	6886.0
HMOX2	6885.0
KDM4C	6867.0
NIPSNAP2	6801.0
PPP1R14A	6799.0
PRKCB	6744.0
ARHGAP11A	6736.0
DOCK7	6716.0
NUP37	6708.0
H3C10	6652.0
MAP3K11	6644.0
MYL12B	6608.0
CDC42	6603.0
WASF2	6601.0
SPTBN1	6494.0
FNBP1	6492.0
RPS27	6477.0
JAG1	6471.0
H2BC8	6334.0
STAM2	6329.0
NUP160	6322.0
NDE1	6318.0
NSFL1C	6268.0
H2BC12	6220.0
ABL1	6174.0
ARPC1B	6122.0
CYFIP1	6113.0
RND3	6111.0
PPP1R12A	6096.0
CENPM	6069.0
ACTB	6053.0
RHOT1	6040.0
CENPL	6013.0
ARHGEF10	6007.0
YWHAQ	5997.0
ARHGEF25	5962.0
H3C4	5911.0
DOCK6	5895.0
VAMP3	5877.0
PRKCA	5835.0
MAPK1	5826.0
KIF14	5793.0
DEPDC1B	5757.0
SEH1L	5744.0
ANKLE2	5726.0
CENPE	5720.0
CENPC	5654.0
CENPU	5624.0
IQGAP2	5610.0
EPSTI1	5560.0
ABCD3	5543.0
SHMT2	5521.0
LIN7B	5512.0
PAK6	5387.0
ARHGEF7	5367.0
H4C3	5297.0
CENPK	5296.0
CIT	5229.0
ARHGAP12	5201.0
MAPK14	5180.0
H2AJ	5141.0
DYNC1LI1	5132.0
CENPQ	5131.0
TMOD3	5097.0
ITSN2	5029.0
PPP2R5C	5016.0
FAM169A	5009.0
CLASP2	4967.0
CDC42BPB	4942.0
TAX1BP3	4936.0
RAPGEF1	4921.0
RANBP2	4890.0
SLK	4885.0
SPATA13	4881.0
SEC13	4854.0
ARHGEF15	4853.0
PRAG1	4831.0
S100A9	4820.0
ARHGAP15	4818.0
VANGL1	4753.0
KIF5B	4750.0
CCDC115	4718.0
ADD3	4707.0
ARHGAP33	4692.0
RHPN1	4687.0
RALBP1	4686.0
LRRC41	4669.0
DOCK2	4642.0
RHOT2	4641.0
RND1	4636.0
ARHGEF40	4593.0
ECT2	4588.0
STIP1	4556.0
RHOV	4479.0
PGRMC2	4473.0
B9D2	4467.0
ARHGDIB	4443.0
MFN1	4419.0
ARAP2	4366.0
TEX2	4349.0
CKAP4	4339.0
PPP2R1A	4310.0
SENP1	4304.0
KIF2A	4282.0
VAPB	4281.0
SGO2	4264.0
PLEKHG5	4260.0
KIF2B	4249.0
TUBA4A	4239.0
DYNLL1	4203.0
PTK2B	4170.0
TUBB2A	4122.0
KLC3	4121.0
PLXNB1	4060.0
PIK3CA	4013.0
H4C2	3987.0
BUB3	3920.0
TUBB2B	3907.0
COPS4	3879.0
YWHAH	3875.0
BUB1	3874.0
WASL	3866.0
TUBA4B	3811.0
CENPO	3792.0
WASF1	3787.0
ARL13B	3770.0
WHAMM	3763.0
ZWINT	3720.0
CCDC88A	3715.0
HSP90AB1	3700.0
WDR6	3699.0
ABL2	3693.0
DIAPH3	3654.0
RHOBTB1	3630.0
TAOK1	3609.0
H4C4	3596.0
ABR	3560.0
DOCK9	3543.0
H3C8	3521.0
PIK3C3	3509.0
PKN2	3479.0
PLK1	3472.0
TMEM59	3449.0
DOCK8	3410.0
ARHGAP31	3397.0
H2AC20	3382.0
RACGAP1	3319.0
ITGB1	3314.0
FARP2	3302.0
NUP107	3276.0
LEMD3	3263.0
SPTAN1	3255.0
PFN2	3247.0
TAGAP	3186.0
DOCK10	3118.0
KIDINS220	3099.0
CEP97	3061.0
H3-3B	3055.0
FAF2	3043.0
PRKCZ	3037.0
ARHGEF39	3025.0
RHOA	3000.0
H2AC18	2954.5
H2AC19	2954.5
PKP4	2931.0
TRIO	2905.0
ARHGEF17	2903.0
CUL3	2861.0
ARHGAP20	2857.0
VRK2	2848.0
TRAK1	2796.0
H2AC7	2792.5
H2BC7	2792.5
BAIAP2	2775.0
MIS12	2770.0
NCF2	2756.0
NCOA2	2754.0
RBBP6	2741.0
H2BC21	2718.0
WIPF1	2711.0
CAV1	2698.0
PIK3R1	2684.0
NF2	2647.0
ROCK2	2635.0
DDX39B	2621.0
NCF4	2618.0
PLEKHG2	2603.0
DAAM1	2586.0
FAM13A	2552.0
NET1	2512.0
SYDE2	2502.0
MYO9A	2433.0
ARAP3	2419.0
SRF	2415.0
SEMA4F	2411.0
MPP7	2361.0
DSP	2356.0
TUBB4B	2340.0
PPP1CC	2315.0
H3-3A	2262.0
CTNNB1	2250.0
ANLN	2249.0
EMC3	2240.0
SHKBP1	2198.0
ARPC5	2177.0
KNL1	2176.0
SAMM50	2164.0
ARFGAP3	2160.0
H2BC5	2100.0
RHOH	2064.0
DLG5	2039.0
NCK2	2034.0
NCK1	2028.0
MYL6	1979.0
RAC3	1971.0
PLXNA1	1961.0
TIAM2	1935.0
PDE5A	1907.0
SRGAP3	1902.0
PPP1CB	1887.0
H2BC17	1857.0
H2BC13	1834.0
H3C2	1828.0
HSPE1	1804.0
GRB7	1777.0
ACTR2	1697.0
CFL1	1670.0
ARPC1A	1646.0
RND2	1580.0
PPP2R5A	1572.0
SKA2	1570.0
DVL2	1535.0
ARHGAP5	1529.0
SOS2	1372.0
NDC80	1352.0
LMNB1	1327.0
RHOBTB2	1316.0
H2BC11	1286.0
KLK2	1249.0
MACO1	1239.0
VANGL2	1215.0
STEAP3	1196.0
YWHAZ	1179.0
ARHGEF26	1176.0
ARHGAP10	1134.0
CDC42EP3	1046.0
CDC42EP4	1024.0
TUBA1A	1018.0
TMEM87A	958.0
SLC4A7	955.0
TFRC	939.0
VCP	920.0
CPSF7	901.0
NUF2	899.0
PIK3R3	869.0
AURKB	823.0
TOR1AIP1	805.0
OSBPL11	754.0
STAM	744.0
CCP110	730.0
GMIP	700.0
FRS3	696.0
ZNF512B	621.0
CDC20	611.0
NUP43	561.0
NDUFS3	522.0
PPP2CB	497.0
CPNE8	470.0
NCKAP1	438.0
STARD13	416.0
OBSCN	376.0
SH3PXD2A	350.0
WDR91	303.0
CCT2	294.0
PPP2R5B	256.0
MEN1	220.0
YWHAB	170.0
TUBB6	150.0
LRRC1	126.0
CHN1	105.0
PFN1	92.0
FGD4	33.0
ARHGEF12	26.0
NGEF	-26.0
PPP2R5E	-53.0
STK38	-75.0
MYH14	-86.0
TMPO	-93.0
ROCK1	-121.0
DLG4	-148.0
MAPRE1	-157.0
PKN1	-168.0
PLEKHG3	-195.0
ALS2	-227.0
TWF1	-235.0
H4C9	-276.0
CTNNA1	-328.0
TUBB4A	-357.0
PARD6B	-371.0
TUBA8	-372.0
ACBD5	-378.0
VAV3	-395.0
PLEKHG4B	-412.0
CCT6A	-434.0
MCF2L	-561.0
GIT1	-596.0
ARHGEF18	-599.0
H2AX	-614.0
VHL	-675.0
LIMK1	-688.0
MYL9	-693.0
DBN1	-740.0
CDC42EP1	-772.0
CHN2	-823.0
PHIP	-866.0
ARHGAP32	-907.0
BAIAP2L1	-950.0
SWAP70	-987.0
KIF2C	-1021.0
FRS2	-1024.0
ARHGAP26	-1029.0
ABI2	-1037.0
TXNL1	-1067.0
FAM135A	-1115.0
ARHGAP21	-1124.0
ARHGDIG	-1155.0
PTK2	-1164.0
LMAN1	-1248.0
CENPA	-1250.0
PRC1	-1291.0
ARHGEF28	-1316.0
IQGAP1	-1341.0
DOCK5	-1343.0
VAV1	-1402.0
BLTP3B	-1529.0
ARHGEF16	-1532.0
TPM4	-1879.0
FGD5	-1932.0
DBT	-1940.0
ITGB3BP	-1974.0
AKAP13	-1997.0
RHOQ	-2003.0
CENPT	-2031.0
FAM91A1	-2040.0
PPP2CA	-2084.0
DDX4	-2114.0
AMIGO2	-2159.0
PARD6A	-2160.5
SCFD1	-2211.0
ACTR3	-2226.0
CDH1	-2234.0
NOXO1	-2306.0
DOCK3	-2378.0
FAM13B	-2414.0
MAD2L1	-2478.0
MYO19	-2491.0
ZW10	-2497.0
DST	-2546.0
ACTG1	-2553.0
SRGAP1	-2562.0
PICALM	-2599.0
CENPH	-2615.0
NOX3	-2633.0
PAK1	-2725.0
DOCK1	-2756.0
KLK3	-2788.0
DYNC1I2	-2797.0
VAV2	-2813.0
FARP1	-2862.0
H2BC26	-2895.0
PIK3R4	-2946.0
CCNE1	-2947.0
ARHGEF3	-2980.0
ARHGEF4	-3119.0
SH3RF1	-3153.0
SCAI	-3269.0
MCAM	-3281.0
TIAM1	-3297.0
RHOBTB3	-3378.0
FILIP1	-3382.0
KCTD3	-3428.0
STOM	-3454.0
HSP90AA1	-3488.0
STMN2	-3537.0
TUBA3D	-3545.0
TUBA1C	-3556.0
FAM83B	-3631.0
KIF5A	-3770.0
UACA	-3777.0
H2AZ2	-3800.0
MAPK11	-3828.0
RHOG	-3953.0
SYDE1	-3956.0
TUBB3	-4002.0
DNMBP	-4084.0
TJP2	-4085.0
SPC25	-4088.0
ARHGAP25	-4123.0
RHOB	-4209.0
ARHGAP29	-4279.0
NDUFA5	-4292.0
JUP	-4358.0
EPHA2	-4383.0
BASP1	-4389.0
BAIAP2L2	-4402.0
RHOD	-4433.0
TRAK2	-4448.0
H2BC1	-4453.0
SKA1	-4482.0
STBD1	-4488.0
BIRC5	-4539.0
PTPN13	-4549.0
TUBA3E	-4662.0
ITSN1	-4678.0
FNBP1L	-4751.0
ARHGEF19	-4769.0
ARHGAP8	-4776.0
ARHGEF11	-4825.0
MYO6	-4877.0
RALGAPA1	-4905.0
RASGRF2	-4909.0
H3C6	-4925.0
NOXA1	-4995.0
MTX1	-5013.0
PLXND1	-5048.0
PLEKHG4	-5063.0
PREX2	-5316.0
MUC13	-5329.0
DYNC1I1	-5334.0
CDC42SE2	-5338.0
SOWAHC	-5374.0
H2AC14	-5418.0
CKB	-5439.0
RRAS2	-5480.0
SPDL1	-5533.0
AKAP12	-5540.0
SLITRK3	-5661.0
HTR7	-5692.0
H2BC3	-5733.0
ARHGAP11B	-5800.0
H4C16	-5871.0
KALRN	-5900.0
BRK1	-5954.0
POTEE	-5992.0
S100A8	-5997.0
MYLK	-6020.0
RHOJ	-6142.0
FMNL2	-6188.0
WASF3	-6206.0
ARHGAP24	-6250.0
ARHGEF10L	-6295.0
SH3BP1	-6300.0
TUBA1B	-6340.0
TUBB1	-6519.0
PLEKHG6	-6527.0
GOPC	-6556.0
GPS1	-6560.0
RHPN2	-6573.0
DOCK4	-6611.0
H3C3	-6688.0
SLC1A5	-6836.0
CDC42BPA	-6877.0
H2BC14	-7035.0
GJA1	-7142.0
CAVIN1	-7143.0
H4C12	-7199.0
ARHGAP44	-7206.0
ARHGAP42	-7214.0
SNAP23	-7253.0
DLC1	-7260.0
TUBA3C	-7269.0
TUBAL3	-7278.0
PAK5	-7280.0
DSG1	-7296.0
ARHGAP22	-7369.0
PCDH7	-7407.0
ARHGAP40	-7526.0
SPC24	-7608.0
RHOU	-7613.0
SLITRK5	-7785.0
ARHGAP39	-7816.0
H3C12	-7844.0
PLD1	-7903.0
ACTC1	-7980.0
ARHGEF5	-8027.0
FERMT2	-8044.0
RASAL2	-8161.0
ARHGAP28	-8297.0
CFTR	-8343.0
SFN	-8574.0
DSG2	-8585.0
IL32	-8730.0
TUBB8	-8942.0
WIPF3	-9061.0

---

REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION

REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION

	1636
set	REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION
setSize	361
pANOVA	6.38e-10
s.dist	0.189
p.adjustANOVA	2.91e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PDIA3	12004
RNF123	11967
MGRN1	11664
FBXW12	11548
RNF4	11536
UBR4	11519
FBXL14	11460
TRIM41	11433
RNF34	11329
FZR1	11268
SEC24B	11267
UBE2F	11232
HERC3	11087
PSMB4	11076
KLHL42	11033
FBXW10	10958
UBE2V2	10901
PSMD4	10893
PSMD13	10870
IKBKB	10825

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PDIA3	12004
RNF123	11967
MGRN1	11664
FBXW12	11548
RNF4	11536
UBR4	11519
FBXL14	11460
TRIM41	11433
RNF34	11329
FZR1	11268
SEC24B	11267
UBE2F	11232
HERC3	11087
PSMB4	11076
KLHL42	11033
FBXW10	10958
UBE2V2	10901
PSMD4	10893
PSMD13	10870
IKBKB	10825
PSMA2	10707
RNF41	10691
UBE2R2	10667
SEC61B	10617
RNF138	10576
HECTD1	10539
ELOB	10535
CDC23	10475
PSMC6	10418
WWP1	10374
FBXO4	10256
UBE2O	10212
NPEPPS	10198
TRIM39	10193
KLHL22	10192
LRSAM1	10114
FBXW9	9987
PSMD3	9979
FBXO10	9971
TRAF7	9926
ASB1	9894
FBXL18	9869
FBXO7	9868
TIRAP	9826
PSMD7	9804
RNF126	9693
PSMC4	9692
ANAPC1	9651
ASB7	9628
SMURF2	9601
PSMD2	9598
FBXL3	9531
UBE2L3	9504
PSMB5	9461
FBXL22	9441
DET1	9365
BTRC	9324
CD14	9244
SEC24C	9238
KBTBD7	9221
HERC2	9108
PSMF1	9002
TAPBP	8971
TPP2	8888
TRIM32	8755
THOP1	8688
PSMB7	8555
UBAC1	8526
LY96	8508
PSMA4	8487
SMURF1	8435
SEC61A1	8418
LONRF1	8405
DCAF1	8391
UNKL	8356
TRIM11	8322
ASB3	8291
CTSS	8214
SEC61G	8192
S100A1	8172
KLHL21	8147
UBE3B	8137
UBE2J1	8049
FBXW11	8014
UBE2J2	7980
PSMB1	7978
PSMA6	7971
ARIH2	7957
AREL1	7943
SEC22B	7883
KLHL20	7870
UBE2M	7791
RNF6	7784
CHUK	7753
FBXW4	7739
CYBA	7724
RNF213	7718
PSME2	7675
ANAPC4	7652
PSMD1	7564
ANAPC5	7558
RPS27A	7499
PSME1	7470
MIB2	7445
GLMN	7441
RNF14	7419
UBE2G1	7365
ERAP2	7250
CDC27	7198
BTBD1	7196
UBE2Q1	7177
TRIM4	7175
UBE3C	7105
PSMA3	7039
PSMA1	6977
PSMD6	6942
UBA7	6913
UBE2L6	6911
TRIM37	6818
PJA2	6804
CDC16	6748
HECTD3	6701
PSMB3	6665
CUL7	6650
PSMD11	6649
PSMD12	6422
PSMB6	6370
GAN	6368
ANAPC10	6338
PSMD5	6295
PSME3	6289
SIAH2	6239
MYLIP	6233
ASB13	6227
FBXW8	6055
PSMD9	5939
VAMP3	5877
UBE2B	5859
FBXO31	5838
UBE2H	5833
ANAPC11	5794
ASB6	5724
ATG14	5723
CDC26	5692
SEC31A	5671
FBXL19	5598
HERC5	5514
UBE2Q2	5502
ATG7	5490
ASB8	5407
PSMB2	5390
UBC	5385
TRIP12	5242
PSMA7	5054
ITCH	5050
KBTBD6	4917
UBR2	4857
SEC13	4854
S100A9	4820
SAR1B	4809
UBR1	4731
RNF114	4711
LRRC41	4669
MYD88	4648
ZNRF2	4598
WSB1	4494
UFL1	4478
FBXW7	4447
HERC4	4439
FBXO9	4405
FBXO21	4404
PSMA8	4378
CANX	4306
FBXW2	4290
UBE2D3	4277
HERC6	4247
RNF25	4237
FBXO44	4218
STX4	4140
TRIM71	4130
FBXO30	4084
MRC2	4075
PSMC2	4047
CUL1	4015
PSMB10	3971
CUL5	3961
HERC1	3880
FBXO11	3860
ANAPC13	3819
RNF19A	3796
TLR6	3795
ANAPC7	3782
RNF220	3778
SEC24D	3773
ITGAV	3747
UBE3D	3722
SKP1	3705
FBXO22	3648
ERAP1	3631
PIK3C3	3509
RNF111	3481
UBE2E1	3470
UBE3A	3358
PSMC3	3323
CCNF	3322
PSMC1	3148
PSME4	3137
PSMC5	3065
SEC24A	3029
FBXO32	3005
UBE2E3	2917
UBA5	2907
CUL3	2861
ELOC	2833
KCTD6	2802
NCF2	2756
RBBP6	2741
SPSB1	2650
NCF4	2618
UBE4A	2509
RNF130	2371
KCTD7	2358
PSMB8	2300
FBXL16	2155
FBXO6	2038
PSMD14	1903
UBE2S	1865
LNPEP	1841
KLHL2	1748
PSMB11	1723
KEAP1	1708
CALR	1632
SEC61A2	1579
UBOX5	1565
UBE2D2	1556
KLHL3	1554
KLHL25	1524
DZIP3	1272
RCHY1	1186
KBTBD8	1150
ZBTB16	1109
NEDD4	1072
RBCK1	914
HLA-C	871
CDC20	611
RNF115	571
TLR1	477
KLHL5	426
ASB17	371
RNF19B	332
FBXW5	304
FGB	275
BECN1	214
UBE2W	159
TLR4	104
TRIM21	-70
RNF7	-73
NEDD4L	-256
DTX3L	-309
UBE2G2	-401
TRIM36	-455
CTSV	-522
LTN1	-609
TRAIP	-627
MKRN1	-634
VHL	-675
KLHL9	-718
SEC23A	-814
ITGB5	-819
HSPA5	-841
SKP2	-864
RNF144B	-983
HACE1	-1005
SPSB4	-1013
FBXL5	-1073
CUL2	-1184
ANAPC2	-1206
FBXO27	-1351
UBA6	-1362
ZNRF1	-1400
TRIM9	-1412
BLMH	-1433
UBE2D1	-1471
FBXL20	-1584
SOCS1	-1703
FBXL13	-1785
FBXO17	-1911
FBXL15	-2061
FBXO41	-2224
RBX1	-2227
UBA52	-2237
UBB	-2335
UBE2U	-2383
FGA	-2515
CBLB	-2538
ASB14	-2586
LNX1	-2594
RNF217	-2595
UBA3	-2699
UBE2V1	-2729
VAMP8	-2887
PSMB9	-2938
PIK3R4	-2946
MEX3C	-2960
ASB4	-3092
FBXO15	-3152
SH3RF1	-3153
SIAH1	-3505
TAP1	-3660
FBXO2	-3703
UBE2K	-3824
UBE2C	-3845
ASB15	-3864
CTSL	-3923
CDC34	-3973
ASB10	-3981
TAP2	-3983
ASB18	-4004
TRIM50	-4184
LRR1	-4192
PSMA5	-4331
TLR2	-4444
HLA-G	-4445
BTBD6	-4460
UBE2Z	-4518
PRKN	-4525
HLA-A	-4744
HMGB1	-4816
STUB1	-4920
UBE2E2	-5024
LMO7	-5044
PSMD8	-5050
KLHL11	-5456
FBXL4	-5609
FBXO40	-5727
SPSB2	-5761
HECTD2	-5801
UBE2D4	-5975
S100A8	-5997
FBXL8	-6004
HLA-E	-6091
ASB2	-6415
FGG	-6723
UBE2N	-6864
B2M	-7174
SNAP23	-7253
HECW2	-7443
SEM1	-7461
ASB16	-7542
FBXL7	-7868
FBXL12	-8149
SOCS3	-8205
ASB5	-8319
KLHL41	-8410
CD36	-8484
RNF182	-8893
HLA-F	-8905
TRIM63	-9231
TRIM69	-9354
HLA-B	-9476
CD207	-9537

---

REACTOME_ADAPTIVE_IMMUNE_SYSTEM

REACTOME_ADAPTIVE_IMMUNE_SYSTEM

	79
set	REACTOME_ADAPTIVE_IMMUNE_SYSTEM
setSize	729
pANOVA	7.69e-10
s.dist	0.134
p.adjustANOVA	3.36e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PILRB	12180
CD79B	12044
SIGLEC8	12037
PDIA3	12004
RNF123	11967
LCK	11904
FCGR3A	11842
PDPK1	11829
GRAP2	11714
CD28	11682
MGRN1	11664
EVL	11654
LAT	11638
AP2M1	11598
NFKBIE	11573
FBXW12	11548
RILP	11538
RNF4	11536
UBR4	11519
PRKACG	11518

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PILRB	12180
CD79B	12044
SIGLEC8	12037
PDIA3	12004
RNF123	11967
LCK	11904
FCGR3A	11842
PDPK1	11829
GRAP2	11714
CD28	11682
MGRN1	11664
EVL	11654
LAT	11638
AP2M1	11598
NFKBIE	11573
FBXW12	11548
RILP	11538
RNF4	11536
UBR4	11519
PRKACG	11518
FBXL14	11460
CD81	11452
CD19	11439
TRIM41	11433
DYNLL2	11413
PIK3CD	11353
RNF34	11329
AP2A2	11289
FZR1	11268
SEC24B	11267
UBE2F	11232
CD101	11101
HERC3	11087
PSMB4	11076
KLHL42	11033
MTOR	11011
PPP2R1B	10998
HLA-DRB5	10959
FBXW10	10958
DCTN3	10909
UBE2V2	10901
PSMD4	10893
PSMD13	10870
IKBKB	10825
CSK	10782
ZAP70	10741
PPP2R5D	10733
PSMA2	10707
RNF41	10691
TRIB3	10681
DYNC1H1	10679
UBE2R2	10667
AP1B1	10665
SEC61B	10617
RNF138	10576
PRR5	10543
HECTD1	10539
ELOB	10535
ACTR1B	10501
CDC23	10475
VASP	10435
PSMC6	10418
INPP5D	10409
PIK3CB	10406
WWP1	10374
ICAM4	10358
KIF22	10355
DNM2	10321
NCR3	10258
FBXO4	10256
PAK2	10228
UBE2O	10212
NPEPPS	10198
TRIM39	10193
KLHL22	10192
LILRB5	10158
ICAM3	10147
DYNC1LI2	10120
LRSAM1	10114
FBXW9	9987
PSMD3	9979
FBXO10	9971
CD3D	9948
TRAF7	9926
ORAI2	9902
ASB1	9894
SOS1	9884
FBXL18	9869
FBXO7	9868
TIRAP	9826
KLC1	9809
PSMD7	9804
AKT1	9802
CD247	9759
RIPK2	9756
RNF126	9693
PSMC4	9692
AP1M2	9672
ANAPC1	9651
SRC	9630
ASB7	9628
SMURF2	9601
SLAMF6	9599
PSMD2	9598
BTN1A1	9565
FBXL3	9531
PPIA	9515
UBE2L3	9504
PSMB5	9461
RAC1	9456
FBXL22	9441
NCR1	9424
RAF1	9421
DET1	9365
BTRC	9324
RAB7A	9267
CD14	9244
SEC24C	9238
KBTBD7	9221
PTPN6	9161
ITGB2	9155
CARD11	9147
HERC2	9108
CALM1	9105
KLC4	9104
KLRB1	9020
ITPR3	9019
BTN3A3	9017
PRKACA	9014
PSMF1	9002
TAPBP	8971
GRB2	8934
TPP2	8888
BTN2A1	8834
RAP1GAP2	8805
TRIM32	8755
NFATC3	8714
THOP1	8688
LILRA2	8637
ITGAL	8602
PSMB7	8555
UBAC1	8526
ICAM2	8521
LY96	8508
PSMA4	8487
KLC2	8445
CTSA	8444
SMURF1	8435
AKT2	8422
SEC61A1	8418
MICA	8414
LONRF1	8405
DCAF1	8391
UNKL	8356
YES1	8329
TRIM11	8322
NFATC2	8308
ASB3	8291
CTSS	8214
SEC61G	8192
LILRA5	8180
S100A1	8172
KLHL21	8147
UBE3B	8137
NFKBIB	8098
LILRB4	8077
UBE2J1	8049
SIPA1	8032
FBXW11	8014
PIK3R2	7993
UBE2J2	7980
PSMB1	7978
PSMA6	7971
ARIH2	7957
CAPZB	7951
AREL1	7943
ITGB7	7891
SEC22B	7883
CD3E	7881
KLHL20	7870
AP2S1	7803
UBE2M	7791
RNF6	7784
HCST	7756
CHUK	7753
FBXW4	7739
CYBA	7724
RNF213	7718
CLTC	7714
DCTN4	7680
PSME2	7675
ANAPC4	7652
CTSB	7649
DCTN6	7640
ACTR10	7623
PSMD1	7564
ANAPC5	7558
RPS27A	7499
PSME1	7470
MIB2	7445
GLMN	7441
RNF14	7419
UBE2G1	7365
LCP2	7278
ERAP2	7250
MICB	7224
CDC27	7198
BTBD1	7196
DCTN1	7179
UBE2Q1	7177
TRIM4	7175
UBE3C	7105
PSMA3	7039
PSMA1	6977
PSMD6	6942
UBA7	6913
UBE2L6	6911
KIF18A	6886
BLK	6844
TRIM37	6818
PJA2	6804
CDC16	6748
PRKCB	6744
HECTD3	6701
PSMB3	6665
CUL7	6650
PSMD11	6649
CDC42	6603
ORAI1	6444
PSMD12	6422
PSMB6	6370
GAN	6368
ACTR1A	6363
ANAPC10	6338
PSMD5	6295
PSME3	6289
SIGLEC1	6276
SIAH2	6239
MYLIP	6233
ASB13	6227
MAPKAP1	6204
STIM1	6123
FBXW8	6055
RELA	6020
PLCG1	6015
HLA-DQB2	5956
PSMD9	5939
VAMP3	5877
UBE2B	5859
FBXO31	5838
UBE2H	5833
AP1M1	5820
ANAPC11	5794
CTSK	5782
AP2A1	5736
ASB6	5724
ATG14	5723
CENPE	5720
CDC26	5692
SEC31A	5671
SFTPD	5668
LAIR1	5625
FBXL19	5598
HERC5	5514
UBE2Q2	5502
CD3G	5500
PDCD1	5491
ATG7	5490
ASB8	5407
PSMB2	5390
UBC	5385
CD34	5245
TRIP12	5242
DYNC1LI1	5132
PTPN11	5117
PSMA7	5054
ITCH	5050
PPP2R5C	5016
KIF11	4974
CD74	4971
NFATC1	4940
HLA-DOB	4929
KBTBD6	4917
UBR2	4857
SEC13	4854
CD8A	4828
S100A9	4820
CTSC	4814
SAR1B	4809
KIF5B	4750
UBR1	4731
CTLA4	4724
RNF114	4711
SIGLEC10	4683
LRRC41	4669
LYN	4661
MYD88	4648
CTSO	4628
BCL10	4610
ZNRF2	4598
DCTN5	4586
WSB1	4494
NPDC1	4490
UFL1	4478
FBXW7	4447
HERC4	4439
FBXO9	4405
FBXO21	4404
RAP1B	4381
PSMA8	4378
AP2B1	4341
PPP2R1A	4310
CANX	4306
CD40	4291
FBXW2	4290
KIF2A	4282
UBE2D3	4277
LGMN	4253
KIF2B	4249
HERC6	4247
TUBA4A	4239
RNF25	4237
FBXO44	4218
DYNLL1	4203
PRKCQ	4181
TAB2	4143
STX4	4140
TRIM71	4130
TUBB2A	4122
KLC3	4121
ITPR1	4088
FBXO30	4084
PTEN	4078
MRC2	4075
PSMC2	4047
CUL1	4015
PIK3CA	4013
PSMB10	3971
CUL5	3961
CTSH	3908
TUBB2B	3907
HERC1	3880
FBXO11	3860
HRAS	3837
ANAPC13	3819
TUBA4B	3811
RNF19A	3796
TLR6	3795
ANAPC7	3782
RNF220	3778
SEC24D	3773
ITGAV	3747
UBE3D	3722
PTPN22	3719
SKP1	3705
CD8B	3697
FBXO22	3648
ERAP1	3631
KIFAP3	3614
TYROBP	3552
PIK3C3	3509
THEM4	3496
RNF111	3481
UBE2E1	3470
RASGRP3	3451
UBE3A	3358
PSMC3	3323
CCNF	3322
RACGAP1	3319
ITGB1	3314
JAML	3310
AP1S3	3259
KIF20A	3253
PSMC1	3148
PSME4	3137
DCTN2	3135
CAPZA1	3088
PSMC5	3065
SEC24A	3029
FBXO32	3005
UBE2E3	2917
UBA5	2907
CUL3	2861
ELOC	2833
KCTD6	2802
NCF2	2756
RBBP6	2741
PIK3R1	2684
SPSB1	2650
RASGRP2	2644
COL3A1	2633
MAP3K7	2632
NCF4	2618
TREML2	2604
UBE4A	2509
SH2D1B	2393
RNF130	2371
KCTD7	2358
TUBB4B	2340
PSMB8	2300
SELL	2239
KIF3B	2165
FBXL16	2155
KIF15	2133
CD200R1	2108
FBXO6	2038
NCK1	2028
PSMD14	1903
BTN3A1	1866
UBE2S	1865
LNPEP	1841
ARF1	1827
KLHL2	1748
PSMB11	1723
KEAP1	1708
SPTBN2	1662
CALR	1632
SEC61A2	1579
PPP2R5A	1572
UBOX5	1565
UBE2D2	1556
KLHL3	1554
KLHL25	1524
PLCG2	1474
HLA-DMB	1461
CLTA	1420
KIF26A	1404
DZIP3	1272
SYK	1248
RICTOR	1224
PIK3AP1	1191
RCHY1	1186
YWHAZ	1179
RAP1A	1154
KBTBD8	1150
ZBTB16	1109
DNM1	1081
NEDD4	1072
KIF23	1051
TUBA1A	1018
OSCAR	957
RBCK1	914
AP1S1	908
HLA-DOA	882
REL	878
HLA-C	871
PIK3R3	869
BLNK	865
CD300LD	860
MLST8	854
NCR3LG1	848
FYB1	843
KLRK1	745
ITPR2	728
PPL	727
BTLA	691
MAP3K14	687
LILRA3	674
CAPZA2	668
CDC20	611
RNF115	571
AKT3	516
PPP2CB	497
TLR1	477
AHCYL1	464
PTPRC	440
IFI30	427
KLHL5	426
CLEC2D	375
ASB17	371
RNF19B	332
FBXW5	304
SIGLEC7	298
FGB	275
PPP2R5B	256
RAPGEF4	246
CD160	238
SLAMF7	237
BECN1	214
TRAF6	213
NECTIN2	192
YWHAB	170
UBE2W	159
TUBB6	150
TREM1	109
TLR4	104
CD300A	78
FYN	61
PPP2R5E	-53
TRIM21	-70
RNF7	-73
RAET1E	-179
PPP3R1	-247
NEDD4L	-256
DTX3L	-309
TUBB4A	-357
TUBA8	-372
LAG3	-398
UBE2G2	-401
TRIM36	-455
ULBP1	-465
CD79A	-494
CTSV	-522
CD33	-545
LTN1	-609
PPP3CB	-612
TRAIP	-627
MKRN1	-634
VHL	-675
KLHL9	-718
MAP3K8	-731
SEC23A	-814
BTN3A2	-816
ITGB5	-819
HSPA5	-841
SKP2	-864
RNF144B	-983
HACE1	-1005
PTPRJ	-1011
SPSB4	-1013
KIF2C	-1021
AP1G1	-1050
FBXL5	-1073
PIANP	-1177
CD86	-1181
CUL2	-1184
ANAPC2	-1206
FKBP1A	-1286
FBXO27	-1351
UBA6	-1362
KIR3DL2	-1382
ZNRF1	-1400
VAV1	-1402
TRIM9	-1412
BLMH	-1433
UBE2D1	-1471
ICAM5	-1577
FBXL20	-1584
ITGA4	-1629
PRKACB	-1645
SOCS1	-1703
CD300LG	-1733
RASGRP1	-1778
FBXL13	-1785
FBXO17	-1911
TRPC1	-2002
PDCD1LG2	-2007
RAPGEF3	-2024
FBXL15	-2061
PPP2CA	-2084
KIF4B	-2093
PPP3CA	-2122
BTNL2	-2140
PAG1	-2198
FBXO41	-2224
RBX1	-2227
NRAS	-2230
CDH1	-2234
UBA52	-2237
HLA-DMA	-2277
NFKBIA	-2315
ICAM1	-2332
UBB	-2335
UBE2U	-2383
ULBP3	-2442
FGA	-2515
CBLB	-2538
KLRG1	-2573
ASB14	-2586
LAIR2	-2591
LNX1	-2594
RNF217	-2595
OSBPL1A	-2603
UBA3	-2699
PAK1	-2725
UBE2V1	-2729
TREML4	-2750
DYNC1I2	-2797
VAMP8	-2887
SIGLEC9	-2902
PSMB9	-2938
PIK3R4	-2946
MEX3C	-2960
KIR3DL1	-3041
ASB4	-3092
HLA-DQA1	-3123
CD22	-3136
HLA-DRB1	-3142
FBXO15	-3152
SH3RF1	-3153
KRAS	-3161
MALT1	-3365
COL2A1	-3502
SIAH1	-3505
CXADR	-3543
TUBA3D	-3545
TUBA1C	-3556
COL1A2	-3644
TAP1	-3660
DAPP1	-3667
TREM2	-3675
NFKB1	-3689
FBXO2	-3703
KIF5A	-3770
CLEC4G	-3803
UBE2K	-3824
UBE2C	-3845
CD96	-3846
ASB15	-3864
HLA-DQB1	-3872
CTSL	-3923
CDC34	-3973
ASB10	-3981
TAP2	-3983
TUBB3	-4002
ASB18	-4004
KIR2DL1	-4018
CLEC2B	-4023
CD4	-4035
VCAM1	-4117
MADCAM1	-4152
TRIM50	-4184
LRR1	-4192
CD274	-4276
CD300C	-4320
PSMA5	-4331
KLRF1	-4431
TLR2	-4444
HLA-G	-4445
BTBD6	-4460
PRKG1	-4485
UBE2Z	-4518
PRKN	-4525
LILRB3	-4571
SIGLEC12	-4595
TUBA3E	-4662
HLA-A	-4744
LILRB1	-4805
HMGB1	-4816
CD300LF	-4891
STUB1	-4920
DNM3	-4963
UBE2E2	-5024
C3	-5027
LMO7	-5044
PSMD8	-5050
BTN2A2	-5118
CD200	-5135
CD226	-5259
DYNC1I1	-5334
COL17A1	-5393
KLHL11	-5456
FBXL4	-5609
KIF3A	-5617
FBXO40	-5727
SPSB2	-5761
HECTD2	-5801
UBE2D4	-5975
KIF3C	-5979
SH3GL2	-5994
S100A8	-5997
FBXL8	-6004
HLA-E	-6091
CRTAM	-6177
CTSF	-6214
PVR	-6225
CD300LB	-6226
TUBA1B	-6340
ASB2	-6415
CD80	-6458
TUBB1	-6519
ITK	-6553
CTSD	-6580
NCR2	-6667
XDH	-6678
FGG	-6723
UBE2N	-6864
PILRA	-6949
BTNL8	-6990
LILRA4	-7024
BTNL9	-7065
HLA-DRA	-7136
B2M	-7174
SNAP23	-7253
TUBA3C	-7269
TUBAL3	-7278
HLA-DPB1	-7342
ICOS	-7355
HLA-DQA2	-7359
CD1D	-7430
HECW2	-7443
SEM1	-7461
ENAH	-7534
ASB16	-7542
CD1A	-7586
COLEC12	-7717
FBXL7	-7868
RAP1GAP	-7884
IFITM1	-7992
KIR2DL4	-8033
SIGLEC11	-8128
FBXL12	-8149
SOCS3	-8205
CD1C	-8238
TRAT1	-8272
COL1A1	-8277
ASB5	-8319
KLHL41	-8410
SIGLEC6	-8444
CD36	-8484
KLRD1	-8604
CD1B	-8665
CD300E	-8770
CAPZA3	-8836
TREML1	-8864
RNF182	-8893
HLA-F	-8905
CD209	-8941
TUBB8	-8942
SIGLEC5	-8944
LILRA1	-9122
CTSE	-9159
TRIM63	-9231
LILRB2	-9264
TRIM69	-9354
HLA-DPA1	-9367
HLA-B	-9476
CD207	-9537
KLRC1	-9609

---

REACTOME_TRANSLATION

REACTOME_TRANSLATION

	1152
set	REACTOME_TRANSLATION
setSize	278
pANOVA	7.78e-10
s.dist	0.214
p.adjustANOVA	3.36e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
EIF2B5	11878
EIF4G1	11781
RPL32	11326
MRPL39	11217
MRPS15	11168
MRPL47	11047
CARS1	10985
KARS1	10871
EEF1D	10869
EEF2	10808
MRPL45	10701
EIF3G	10694
MRPS7	10652
EIF3K	10647
MRPL38	10633
SEC61B	10617
RPL26	10573
RPN1	10453
MARS1	10449
MRPL41	10421

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
EIF2B5	11878.0
EIF4G1	11781.0
RPL32	11326.0
MRPL39	11217.0
MRPS15	11168.0
MRPL47	11047.0
CARS1	10985.0
KARS1	10871.0
EEF1D	10869.0
EEF2	10808.0
MRPL45	10701.0
EIF3G	10694.0
MRPS7	10652.0
EIF3K	10647.0
MRPL38	10633.0
SEC61B	10617.0
RPL26	10573.0
RPN1	10453.0
MARS1	10449.0
MRPL41	10421.0
EIF3B	10380.0
EIF3A	10354.0
CARS2	10207.0
EIF4A1	10151.0
RPS9	10077.0
MRPS22	9961.0
LARS2	9958.0
EIF2B3	9952.0
MRPS18A	9946.0
MRPL18	9789.0
RPL6	9786.0
EARS2	9754.0
EIF3J	9709.0
RPL27A	9619.0
MRPL36	9482.0
RPN2	9419.0
RPL19	9400.0
TARS1	9360.0
MRPL34	9350.0
MRPL9	9333.0
RPL34	9275.0
MRPL21	9243.0
RPL14	9168.0
MRPS31	9162.0
SRP68	9160.0
HARS1	9154.0
RPL41	9118.0
MRPL27	9044.0
HARS2	8986.0
MRRF	8879.0
NARS1	8770.0
MRPS5	8729.0
RPLP1	8728.0
GADD45GIP1	8680.0
EIF5	8480.0
SEC61A1	8418.0
SARS2	8269.0
RPS15	8218.0
SEC61G	8192.0
MRPL2	8173.0
MRPS16	8163.0
LARS1	8123.0
PABPC1	8106.0
RPL22	8037.0
MRPL58	8029.0
RARS2	8028.0
YARS2	8012.0
MRPS35	8002.0
VARS1	7958.0
MRPS27	7937.0
IARS2	7905.0
MRPL13	7832.0
MTRF1L	7754.0
OXA1L	7669.0
MRPL32	7619.0
EIF3M	7554.0
MRPL30	7541.0
RPS27A	7499.0
EEF1G	7442.0
YARS1	7415.0
AURKAIP1	7363.0
MRPL24	7333.0
RPS23	7245.0
MRPL57	7226.0
RPS10	7219.0
SPCS2	7171.0
MRPL46	7088.0
EIF4H	7028.0
AIMP1	6920.0
EIF2B1	6902.0
ETF1	6849.0
RPS20	6789.0
MRPS11	6737.0
TRMT112	6663.0
MRPL53	6575.0
IARS1	6524.0
MRPL44	6505.0
RPS27	6477.0
EIF2S1	6395.0
EIF3I	6291.0
MRPL23	6279.0
FARS2	6213.0
RPS2	6180.0
RPS15A	6160.0
MRPS10	6085.0
MARS2	6030.0
RPS16	6017.0
RPL15	5994.0
MRPS14	5918.0
MTIF3	5885.0
RPL11	5878.0
MRPS12	5803.0
GFM2	5802.0
EIF3L	5761.0
EIF2S2	5673.0
SRP54	5628.0
AARS1	5453.0
NARS2	5433.0
RPL35A	5375.0
MRPL22	5236.0
SRPRB	5057.0
MRPS18B	4968.0
EIF3D	4852.0
MRPL50	4825.0
EIF4B	4722.0
EIF3E	4624.0
RPL29	4480.0
MRPL1	4477.0
MRPS18C	4454.0
MRPS17	4450.0
SSR1	4444.0
RPS14	4403.0
EIF4EBP1	4340.0
RPL28	4311.0
MRPL55	4252.0
MRPL49	4219.0
MRPL19	4206.0
N6AMT1	4118.0
APEH	4098.0
ERAL1	4032.0
RPL31	3951.0
DDOST	3936.0
RPS3A	3917.0
DARS2	3761.0
AARS2	3616.0
VARS2	3562.0
RPL35	3510.0
EIF4E	3463.0
MRPL28	3290.0
MRPS6	3214.0
RPL18	3205.0
RPL9	3178.0
RPS29	3176.0
RPS24	3174.0
PPA1	3113.0
RARS1	2971.0
SRP72	2953.0
WARS1	2901.0
MRPS9	2879.0
DAP3	2824.0
SEC11A	2733.0
GSPT1	2677.0
RPL21	2628.0
MRPL35	2568.0
RPS3	2461.0
RPL4	2357.0
TARS2	2326.0
RPS27L	2306.0
EIF2B4	2299.0
MRPL51	2229.0
RPL10A	2208.0
RPL12	2178.0
MRPL42	2062.0
EIF2B2	1996.0
MTIF2	1916.0
FARSB	1900.0
RPL13A	1771.5
MRPL37	1744.0
MRPL20	1731.0
PARS2	1656.0
FARSA	1652.0
SEC61A2	1579.0
FAU	1541.0
MRPS2	1521.0
WARS2	1508.0
RPL36	1472.0
EIF3F	1338.0
RPS21	1329.0
MRPS26	1145.0
RPL37	1116.0
RPS18	992.0
RPL30	897.0
MRPL12	828.0
PTCD3	756.0
MRPL4	540.0
RPS6	524.0
RPS7	463.0
MRPL11	348.0
MRPL52	83.0
TSFM	17.0
MRPL15	13.0
SPCS3	-28.0
MRPS23	-64.0
TUFM	-79.0
MRPL14	-106.0
EIF5B	-125.0
SEC11C	-223.0
RPL18A	-240.0
RPL23	-261.0
RPL27	-270.0
MRPS25	-381.0
RPLP0	-487.0
MRPL43	-530.0
MRPL54	-548.0
CHCHD1	-664.0
EIF4A2	-739.0
PPA2	-746.0
SPCS1	-953.0
MRPS28	-1105.0
MRPL17	-1153.0
MRPS21	-1161.0
MTFMT	-1236.0
AIMP2	-1407.0
EEF1A1	-1425.0
EEF1E1	-1460.0
GARS1	-1480.0
SSR2	-1504.0
RPS13	-1554.0
GFM1	-1605.0
MRPS33	-1610.0
MRPL10	-1746.0
DARS1	-1958.0
RPL26L1	-2195.0
RPSA	-2216.0
UBA52	-2237.0
RPL7	-2286.0
RPS5	-2392.0
SRP19	-2480.0
MRPL16	-2554.0
RPS28	-2610.0
RPL36AL	-2643.5
EEF1A2	-2686.0
SRP9	-2759.0
SRPRA	-2817.0
RPS12	-2916.0
MRPL48	-2974.0
RPL22L1	-3311.0
EPRS1	-3323.0
RPL39L	-3504.0
EIF3H	-3521.0
EEF1B2	-3628.0
RPL5	-3668.0
TRAM1	-3717.0
RPS11	-4060.0
RPL3L	-4134.0
MRPS30	-4164.0
MRPS24	-4173.0
SRP14	-4231.0
RPS19	-4241.0
MRPS34	-4342.0
RPL17	-4430.0
RPL3	-4491.0
RPLP2	-4579.0
RPL7A	-4734.0
RPL23A	-4959.0
MRPL33	-5119.0
RPL10L	-5285.0
RPL24	-5518.0
MRPL40	-6068.0
RPL38	-6279.0
RPL13	-6322.0
RPL8	-6372.0
RPS8	-6455.0
RPS25	-6687.0
MRPL3	-6732.0
RPL37A	-7080.0
RPS26	-8718.0
SSR3	-8737.0

---

REACTOME_DNA_REPLICATION

REACTOME_DNA_REPLICATION

	1113
set	REACTOME_DNA_REPLICATION
setSize	178
pANOVA	2.22e-09
s.dist	0.26
p.adjustANOVA	9.35e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2BC15	11524
H4C5	11447
H2BC6	11322
FZR1	11268
ORC1	11169
PSMB4	11076
PSMD4	10893
PSMD13	10870
H2AZ1	10867
POLD4	10789
MCM7	10739
PSMA2	10707
POLD1	10687
RPA1	10676
CDC23	10475
ANAPC15	10466
PSMC6	10418
PSMD3	9979
KPNA6	9820
PSMD7	9804

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2BC15	11524.0
H4C5	11447.0
H2BC6	11322.0
FZR1	11268.0
ORC1	11169.0
PSMB4	11076.0
PSMD4	10893.0
PSMD13	10870.0
H2AZ1	10867.0
POLD4	10789.0
MCM7	10739.0
PSMA2	10707.0
POLD1	10687.0
RPA1	10676.0
CDC23	10475.0
ANAPC15	10466.0
PSMC6	10418.0
PSMD3	9979.0
KPNA6	9820.0
PSMD7	9804.0
PSMC4	9692.0
ANAPC1	9651.0
MCM2	9629.0
PSMD2	9598.0
H2AC4	9477.0
PSMB5	9461.0
POLD2	9355.0
H4C6	9077.0
PSMF1	9002.0
POLE	8933.0
H3C11	8908.0
H2BC10	8901.0
POLA2	8682.0
PSMB7	8555.0
LIG1	8548.0
PSMA4	8487.0
RFC2	8432.0
H2AC6	8277.0
H4C11	8241.0
H4C13	8117.0
ANAPC16	8064.0
H4C1	8017.0
PSMB1	7978.0
PSMA6	7971.0
DNA2	7894.0
H2AC8	7728.0
CDC45	7713.0
PSME2	7675.0
ANAPC4	7652.0
PSMD1	7564.0
ANAPC5	7558.0
H2BC4	7539.0
RPS27A	7499.0
PSME1	7470.0
MCM8	7433.0
H3C1	7395.0
H2BC9	7228.5
H3C7	7228.5
CDC27	7198.0
H4C8	7058.0
PSMA3	7039.0
PSMA1	6977.0
PSMD6	6942.0
CDC16	6748.0
PSMB3	6665.0
H3C10	6652.0
PSMD11	6649.0
FEN1	6610.0
PSMD12	6422.0
PRIM2	6418.0
PSMB6	6370.0
ANAPC10	6338.0
H2BC8	6334.0
PSMD5	6295.0
PSME3	6289.0
MCM4	6281.0
H2BC12	6220.0
PSMD9	5939.0
H3C4	5911.0
ANAPC11	5794.0
ORC5	5764.0
CDC26	5692.0
ORC6	5505.0
CDC6	5426.0
PSMB2	5390.0
UBC	5385.0
H4C3	5297.0
RPA2	5194.0
ORC3	5191.0
H2AJ	5141.0
RFC5	5072.0
PSMA7	5054.0
RFC4	4504.0
PSMA8	4378.0
MCM5	4177.0
PSMC2	4047.0
CUL1	4015.0
H4C2	3987.0
PSMB10	3971.0
MCM3	3886.0
ANAPC7	3782.0
SKP1	3705.0
H4C4	3596.0
H3C8	3521.0
UBE2E1	3470.0
H2AC20	3382.0
POLE3	3344.0
ORC4	3333.0
PSMC3	3323.0
PSMC1	3148.0
RPA3	3146.0
PSME4	3137.0
GINS2	3128.0
PSMC5	3065.0
H3-3B	3055.0
GINS3	2975.0
H2AC18	2954.5
H2AC19	2954.5
H2AC7	2792.5
H2BC7	2792.5
H2BC21	2718.0
RFC3	2692.0
PSMB8	2300.0
GINS1	2279.0
H3-3A	2262.0
GMNN	2115.0
H2BC5	2100.0
PSMD14	1903.0
UBE2S	1865.0
H2BC17	1857.0
H2BC13	1834.0
H3C2	1828.0
PSMB11	1723.0
H2BC11	1286.0
POLE2	695.0
PCNA	570.0
PRIM1	283.0
KPNB1	32.0
RFC1	4.0
H4C9	-276.0
H2AX	-614.0
GINS4	-690.0
SKP2	-864.0
KPNA1	-925.0
ANAPC2	-1206.0
UBE2D1	-1471.0
POLD3	-1564.0
CDT1	-1582.0
RBX1	-2227.0
UBA52	-2237.0
ORC2	-2295.0
CDK2	-2309.0
UBB	-2335.0
MCM10	-2444.0
POLE4	-2612.0
CDC7	-2614.0
H2BC26	-2895.0
PSMB9	-2938.0
CCNE1	-2947.0
MCM6	-3207.0
CCNE2	-3373.0
H2AZ2	-3800.0
UBE2C	-3845.0
CCNA1	-4120.0
PSMA5	-4331.0
H2BC1	-4453.0
H3C6	-4925.0
PSMD8	-5050.0
H2AC14	-5418.0
H2BC3	-5733.0
H4C16	-5871.0
CCNA2	-5945.0
DBF4	-6276.0
H3C3	-6688.0
H2BC14	-7035.0
H4C12	-7199.0
SEM1	-7461.0
H3C12	-7844.0

---

REACTOME_DNA_REPLICATION_PRE_INITIATION

REACTOME_DNA_REPLICATION_PRE_INITIATION

	1101
set	REACTOME_DNA_REPLICATION_PRE_INITIATION
setSize	150
pANOVA	2.74e-09
s.dist	0.281
p.adjustANOVA	1.13e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2BC15	11524
H4C5	11447
H2BC6	11322
FZR1	11268
ORC1	11169
PSMB4	11076
PSMD4	10893
PSMD13	10870
H2AZ1	10867
MCM7	10739
PSMA2	10707
RPA1	10676
CDC23	10475
ANAPC15	10466
PSMC6	10418
PSMD3	9979
KPNA6	9820
PSMD7	9804
PSMC4	9692
ANAPC1	9651

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2BC15	11524.0
H4C5	11447.0
H2BC6	11322.0
FZR1	11268.0
ORC1	11169.0
PSMB4	11076.0
PSMD4	10893.0
PSMD13	10870.0
H2AZ1	10867.0
MCM7	10739.0
PSMA2	10707.0
RPA1	10676.0
CDC23	10475.0
ANAPC15	10466.0
PSMC6	10418.0
PSMD3	9979.0
KPNA6	9820.0
PSMD7	9804.0
PSMC4	9692.0
ANAPC1	9651.0
MCM2	9629.0
PSMD2	9598.0
H2AC4	9477.0
PSMB5	9461.0
H4C6	9077.0
PSMF1	9002.0
POLE	8933.0
H3C11	8908.0
H2BC10	8901.0
POLA2	8682.0
PSMB7	8555.0
PSMA4	8487.0
H2AC6	8277.0
H4C11	8241.0
H4C13	8117.0
ANAPC16	8064.0
H4C1	8017.0
PSMB1	7978.0
PSMA6	7971.0
H2AC8	7728.0
CDC45	7713.0
PSME2	7675.0
ANAPC4	7652.0
PSMD1	7564.0
ANAPC5	7558.0
H2BC4	7539.0
RPS27A	7499.0
PSME1	7470.0
MCM8	7433.0
H3C1	7395.0
H2BC9	7228.5
H3C7	7228.5
CDC27	7198.0
H4C8	7058.0
PSMA3	7039.0
PSMA1	6977.0
PSMD6	6942.0
CDC16	6748.0
PSMB3	6665.0
H3C10	6652.0
PSMD11	6649.0
PSMD12	6422.0
PRIM2	6418.0
PSMB6	6370.0
ANAPC10	6338.0
H2BC8	6334.0
PSMD5	6295.0
PSME3	6289.0
MCM4	6281.0
H2BC12	6220.0
PSMD9	5939.0
H3C4	5911.0
ANAPC11	5794.0
ORC5	5764.0
CDC26	5692.0
ORC6	5505.0
CDC6	5426.0
PSMB2	5390.0
UBC	5385.0
H4C3	5297.0
RPA2	5194.0
ORC3	5191.0
H2AJ	5141.0
PSMA7	5054.0
MCM5	4177.0
PSMC2	4047.0
H4C2	3987.0
PSMB10	3971.0
MCM3	3886.0
ANAPC7	3782.0
H4C4	3596.0
H3C8	3521.0
UBE2E1	3470.0
H2AC20	3382.0
POLE3	3344.0
ORC4	3333.0
PSMC3	3323.0
PSMC1	3148.0
RPA3	3146.0
PSMC5	3065.0
H3-3B	3055.0
H2AC18	2954.5
H2AC19	2954.5
H2AC7	2792.5
H2BC7	2792.5
H2BC21	2718.0
PSMB8	2300.0
H3-3A	2262.0
GMNN	2115.0
H2BC5	2100.0
PSMD14	1903.0
UBE2S	1865.0
H2BC17	1857.0
H2BC13	1834.0
H3C2	1828.0
H2BC11	1286.0
POLE2	695.0
PRIM1	283.0
KPNB1	32.0
H4C9	-276.0
H2AX	-614.0
KPNA1	-925.0
ANAPC2	-1206.0
UBE2D1	-1471.0
CDT1	-1582.0
UBA52	-2237.0
ORC2	-2295.0
CDK2	-2309.0
UBB	-2335.0
MCM10	-2444.0
POLE4	-2612.0
CDC7	-2614.0
H2BC26	-2895.0
PSMB9	-2938.0
MCM6	-3207.0
H2AZ2	-3800.0
UBE2C	-3845.0
PSMA5	-4331.0
H2BC1	-4453.0
H3C6	-4925.0
PSMD8	-5050.0
H2AC14	-5418.0
H2BC3	-5733.0
H4C16	-5871.0
DBF4	-6276.0
H3C3	-6688.0
H2BC14	-7035.0
H4C12	-7199.0
SEM1	-7461.0
H3C12	-7844.0

---

REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1

REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1

	1272
set	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1
setSize	229
pANOVA	2.89e-09
s.dist	0.228
p.adjustANOVA	1.16e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
AXIN1	11805
CREBBP	11715
TCF3	11610
H2BC15	11524
KMT2D	11499
SMARCA4	11496
H4C5	11447
SMARCB1	11429
AGO1	11345
H2BC6	11322
SMARCC2	11212
KMT2B	11211
PSMB4	11076
PSMD4	10893
PSMD13	10870
H2AZ1	10867
SETD1A	10831
PSMA2	10707
ARID1A	10632
NR4A3	10627

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
AXIN1	11805.0
CREBBP	11715.0
TCF3	11610.0
H2BC15	11524.0
KMT2D	11499.0
SMARCA4	11496.0
H4C5	11447.0
SMARCB1	11429.0
AGO1	11345.0
H2BC6	11322.0
SMARCC2	11212.0
KMT2B	11211.0
PSMB4	11076.0
PSMD4	10893.0
PSMD13	10870.0
H2AZ1	10867.0
SETD1A	10831.0
PSMA2	10707.0
ARID1A	10632.0
NR4A3	10627.0
LGALS3	10461.0
PSMC6	10418.0
SETD1B	10015.0
KMT2C	9984.0
PSMD3	9979.0
PSMD7	9804.0
IL2	9735.0
AGO2	9717.0
PSMC4	9692.0
SRC	9630.0
PSMD2	9598.0
WDR5	9587.0
LMO2	9499.0
H2AC4	9477.0
PSMB5	9461.0
TNRC6C	9415.0
EP300	9390.0
ELF2	9352.0
KAT2B	9295.0
IL2RA	9186.0
H4C6	9077.0
PSMF1	9002.0
ELF1	8952.0
GP1BA	8928.0
H3C11	8908.0
H2BC10	8901.0
KMT2A	8841.0
PF4	8810.0
ARID1B	8673.0
PSMB7	8555.0
PSMA4	8487.0
CCNH	8458.0
ACTL6A	8382.0
NFATC2	8308.0
H2AC6	8277.0
H4C11	8241.0
PML	8234.0
H4C13	8117.0
SMARCC1	8102.0
H4C1	8017.0
PSMB1	7978.0
PSMA6	7971.0
CSNK2A1	7758.0
H2AC8	7728.0
PSME2	7675.0
TNRC6A	7634.0
PSMD1	7564.0
H2BC4	7539.0
RPS27A	7499.0
PSME1	7470.0
H3C1	7395.0
KMT2E	7299.0
ZFPM1	7275.0
H2BC9	7228.5
H3C7	7228.5
H4C8	7058.0
PSMA3	7039.0
PSMA1	6977.0
SMARCD2	6948.0
PSMD6	6942.0
BLK	6844.0
PRKCB	6744.0
PSMB3	6665.0
PHC2	6654.0
H3C10	6652.0
PSMD11	6649.0
PSMD12	6422.0
HIPK2	6408.0
PSMB6	6370.0
H2BC8	6334.0
PSMD5	6295.0
PSME3	6289.0
H2BC12	6220.0
RING1	6185.0
ABL1	6174.0
TNRC6B	6144.0
CDK7	6114.0
CBX4	6103.0
LDB1	6071.0
HDAC1	6062.0
SMARCA2	5954.0
CSNK2A2	5953.0
PSMD9	5939.0
H3C4	5911.0
CTSK	5782.0
SIN3A	5710.0
CSNK2B	5559.0
PBRM1	5510.0
SIN3B	5452.0
PSMB2	5390.0
UBC	5385.0
BMI1	5313.0
H4C3	5297.0
CBX8	5208.0
H2AJ	5141.0
GPAM	5127.0
PTPN11	5117.0
CCND3	5083.0
PSMA7	5054.0
ITCH	5050.0
PHC3	4783.0
CTLA4	4724.0
SCMH1	4529.0
PSMA8	4378.0
RUNX2	4363.0
GATA3	4254.0
PRKCQ	4181.0
PSMC2	4047.0
SOCS4	4014.0
H4C2	3987.0
PSMB10	3971.0
PHC1	3804.0
TCF12	3739.0
H4C4	3596.0
MYB	3572.0
H3C8	3521.0
AGO3	3420.0
H2AC20	3382.0
PRMT1	3343.0
PSMC3	3323.0
PSMC1	3148.0
PSME4	3137.0
PSMC5	3065.0
H3-3B	3055.0
H2AC18	2954.5
H2AC19	2954.5
IL3	2873.0
RYBP	2853.0
CBX2	2819.0
SMARCD1	2809.0
KCTD6	2802.0
H2AC7	2792.5
H2BC7	2792.5
H2BC21	2718.0
GATA2	2450.0
PSMB8	2300.0
H3-3A	2262.0
H2BC5	2100.0
PSMD14	1903.0
H2BC17	1857.0
ESR1	1837.0
H2BC13	1834.0
H3C2	1828.0
PSMB11	1723.0
ARID2	1517.0
H2BC11	1286.0
MOV10	1158.0
CBFB	714.0
CBX6	622.0
YAF2	315.0
DPY30	230.0
CDK6	85.0
H4C9	-276.0
MNAT1	-336.0
CTSV	-522.0
H2AX	-614.0
MYL9	-693.0
ASH2L	-865.0
CCND1	-1519.0
PCGF5	-1539.0
RUNX1	-1638.0
RBBP5	-1889.0
UBA52	-2237.0
UBB	-2335.0
RNF2	-2391.0
TP73	-2448.0
SPI1	-2508.0
CLDN5	-2837.0
H2BC26	-2895.0
RSPO3	-2899.0
ITGA2B	-2910.0
PSMB9	-2938.0
H2AZ2	-3800.0
CTSL	-3923.0
PRMT6	-4318.0
PSMA5	-4331.0
CCND2	-4351.0
SERPINB13	-4368.0
H2BC1	-4453.0
H3C6	-4925.0
PSMD8	-5050.0
AGO4	-5113.0
SMARCE1	-5238.0
H2AC14	-5418.0
ACTL6B	-5469.0
YAP1	-5728.0
H2BC3	-5733.0
PAX5	-5770.0
AUTS2	-5784.0
H4C16	-5871.0
THBS1	-6013.0
SMARCD3	-6048.0
TJP1	-6230.0
LMO1	-6318.0
TAL1	-6609.0
H3C3	-6688.0
H2BC14	-7035.0
TNFRSF18	-7183.0
H4C12	-7199.0
LIFR	-7310.0
SEM1	-7461.0
NFE2	-7492.0
MIR27A	-7560.0
H3C12	-7844.0
SOCS3	-8205.0
OCLN	-8300.0
CR1	-8489.0
IFNG	-8567.5
CSF2	-8958.0

---

REACTOME_REGULATION_OF_TP53_ACTIVITY

REACTOME_REGULATION_OF_TP53_ACTIVITY

	926
set	REACTOME_REGULATION_OF_TP53_ACTIVITY
setSize	156
pANOVA	2.97e-09
s.dist	0.275
p.adjustANOVA	1.16e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
BRD1	12058
PDPK1	11829
BRPF1	11679
RNF34	11329
GATAD2A	11072
MTOR	11011
BANP	11002
PPP2R1B	10998
USP7	10931
CHD3	10888
RAD9A	10850
PIP4P1	10816
DAXX	10716
RPA1	10676
PRR5	10543
PIP4K2A	10408
TAF4	10162
RMI2	10057
CHD4	10037
RMI1	9852

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
BRD1	12058
PDPK1	11829
BRPF1	11679
RNF34	11329
GATAD2A	11072
MTOR	11011
BANP	11002
PPP2R1B	10998
USP7	10931
CHD3	10888
RAD9A	10850
PIP4P1	10816
DAXX	10716
RPA1	10676
PRR5	10543
PIP4K2A	10408
TAF4	10162
RMI2	10057
CHD4	10037
RMI1	9852
TAF13	9847
AKT1	9802
CDK5R1	9783
PRKAB1	9761
PLK3	9710
RFFL	9452
SMYD2	9416
EP300	9390
KMT5A	9179
STK11	9027
PHF20	8925
PRMT5	8850
KAT6A	8784
MAP2K6	8671
RFC2	8432
AKT2	8422
EHMT1	8321
PML	8234
TOPBP1	8095
DNA2	7894
TAF3	7849
BLM	7764
CSNK2A1	7758
PIN1	7723
TAF2	7715
PRKAB2	7695
NOC2L	7694
MBD3	7608
CDK5	7545
RPS27A	7499
TAF4B	7454
RBBP8	7402
EHMT2	7223
SUPT16H	6552
ZNF385A	6469
DYRK2	6420
HIPK2	6408
TAF1L	6402
TP53INP1	6350
PIP4K2B	6253
MAPKAP1	6204
MDM4	6157
JMY	6120
HDAC1	6062
CSNK2A2	5953
PRKAA1	5866
MEAF6	5790
TBP	5601
CSNK2B	5559
TOP3A	5504
UBC	5385
PRKAG2	5343
AURKA	5237
RPA2	5194
MAPK14	5180
MDM2	5073
RFC5	5072
PPP2R5C	5016
KAT5	5000
CHEK1	4981
TAF7	4746
RFC4	4504
PPP2R1A	4310
POU4F1	4082
BRPF3	4071
WRN	4033
TAF15	4012
GATAD2B	3962
RBBP4	3878
BRIP1	3816
HIPK1	3677
MRE11	3571
MAPKAPK5	3566
TP53	3499
MTA2	3431
BRD7	3149
RPA3	3146
BRCA1	2780
RFC3	2692
TTC5	2683
PRKAG1	2584
SGK1	2406
USP2	2228
ATR	2151
RAD9B	2147
ATM	2137
ING5	2015
TAF6	1945
CHEK2	1906
TAF12	1849
TAF5	1730
PRDM1	1581
PPP1R13B	1543
CDK1	1360
RICTOR	1224
RAD1	1126
PIP4K2C	856
MLST8	854
AURKB	823
ING2	816
TPX2	786
AKT3	516
PPP2CB	497
ATRIP	448
CDKN2A	229
TAF9	-183
TP53RK	-391
L3MBTL1	-677
NBN	-689
SSRP1	-796
TAF11	-999
RAD50	-1348
PPP1R13L	-1666
RHNO1	-1864
POU4F2	-1871
PPP2CA	-2084
UBA52	-2237
SETD9	-2288
CDK2	-2309
UBB	-2335
TP73	-2448
NUAK1	-2855
EXO1	-3131
BARD1	-3201
CCNG1	-3203
RAD17	-3609
MAPK11	-3828
CCNA1	-4120
PRKAA2	-4922
TAF10	-5681
PRKAG3	-5700
CCNA2	-5945
HUS1	-5999
TP63	-6137
TP53BP2	-6425
HDAC2	-7451

---

REACTOME_SYNTHESIS_OF_DNA

REACTOME_SYNTHESIS_OF_DNA

	1109
set	REACTOME_SYNTHESIS_OF_DNA
setSize	119
pANOVA	3.92e-09
s.dist	0.312
p.adjustANOVA	1.5e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FZR1	11268
ORC1	11169
PSMB4	11076
PSMD4	10893
PSMD13	10870
POLD4	10789
MCM7	10739
PSMA2	10707
POLD1	10687
RPA1	10676
CDC23	10475
ANAPC15	10466
PSMC6	10418
PSMD3	9979
PSMD7	9804
PSMC4	9692
ANAPC1	9651
MCM2	9629
PSMD2	9598
PSMB5	9461

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FZR1	11268
ORC1	11169
PSMB4	11076
PSMD4	10893
PSMD13	10870
POLD4	10789
MCM7	10739
PSMA2	10707
POLD1	10687
RPA1	10676
CDC23	10475
ANAPC15	10466
PSMC6	10418
PSMD3	9979
PSMD7	9804
PSMC4	9692
ANAPC1	9651
MCM2	9629
PSMD2	9598
PSMB5	9461
POLD2	9355
PSMF1	9002
POLE	8933
POLA2	8682
PSMB7	8555
LIG1	8548
PSMA4	8487
RFC2	8432
ANAPC16	8064
PSMB1	7978
PSMA6	7971
DNA2	7894
CDC45	7713
PSME2	7675
ANAPC4	7652
PSMD1	7564
ANAPC5	7558
RPS27A	7499
PSME1	7470
MCM8	7433
CDC27	7198
PSMA3	7039
PSMA1	6977
PSMD6	6942
CDC16	6748
PSMB3	6665
PSMD11	6649
FEN1	6610
PSMD12	6422
PRIM2	6418
PSMB6	6370
ANAPC10	6338
PSMD5	6295
PSME3	6289
MCM4	6281
PSMD9	5939
ANAPC11	5794
ORC5	5764
CDC26	5692
ORC6	5505
CDC6	5426
PSMB2	5390
UBC	5385
RPA2	5194
ORC3	5191
RFC5	5072
PSMA7	5054
RFC4	4504
PSMA8	4378
MCM5	4177
PSMC2	4047
CUL1	4015
PSMB10	3971
MCM3	3886
ANAPC7	3782
SKP1	3705
UBE2E1	3470
POLE3	3344
ORC4	3333
PSMC3	3323
PSMC1	3148
RPA3	3146
PSME4	3137
GINS2	3128
PSMC5	3065
GINS3	2975
RFC3	2692
PSMB8	2300
GINS1	2279
GMNN	2115
PSMD14	1903
UBE2S	1865
PSMB11	1723
POLE2	695
PCNA	570
PRIM1	283
RFC1	4
GINS4	-690
SKP2	-864
ANAPC2	-1206
UBE2D1	-1471
POLD3	-1564
CDT1	-1582
RBX1	-2227
UBA52	-2237
ORC2	-2295
CDK2	-2309
UBB	-2335
POLE4	-2612
PSMB9	-2938
CCNE1	-2947
MCM6	-3207
CCNE2	-3373
UBE2C	-3845
CCNA1	-4120
PSMA5	-4331
PSMD8	-5050
CCNA2	-5945
SEM1	-7461

---

REACTOME_ORGANELLE_BIOGENESIS_AND_MAINTENANCE

REACTOME_ORGANELLE_BIOGENESIS_AND_MAINTENANCE

	289
set	REACTOME_ORGANELLE_BIOGENESIS_AND_MAINTENANCE
setSize	277
pANOVA	5.1e-09
s.dist	0.204
p.adjustANOVA	1.9e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CSNK1D	11871
CEP250	11821
CREBBP	11715
ALAS1	11629
MCHR1	11604
ATP5MF	11559
DYNLL2	11413
PCNT	11389
UNC119B	11386
MEF2D	10950
DCTN3	10909
USP46	10792
ATP5F1B	10762
DNAJC11	10760
DYNC1H1	10679
YWHAE	10677
HAUS5	10645
PAFAH1B1	10395
IFT140	10360
CEP152	10291

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CSNK1D	11871
CEP250	11821
CREBBP	11715
ALAS1	11629
MCHR1	11604
ATP5MF	11559
DYNLL2	11413
PCNT	11389
UNC119B	11386
MEF2D	10950
DCTN3	10909
USP46	10792
ATP5F1B	10762
DNAJC11	10760
DYNC1H1	10679
YWHAE	10677
HAUS5	10645
PAFAH1B1	10395
IFT140	10360
CEP152	10291
CCT5	10235
NCOR1	10213
IMMT	10133
MED1	10131
DYNC2I2	10111
ATP5PD	9977
PRKAB1	9761
RAB3IP	9753
HSPA9	9718
CRTC1	9690
YWHAG	9563
CENPJ	9539
CSNK1E	9526
CCT8	9436
TCP1	9406
TCTN1	9399
LZTFL1	9281
CCT4	9278
CEP290	9276
CLASP1	9232
EXOC7	9225
MKS1	9202
CLUAP1	9176
CALM1	9105
RAB8A	9068
HAUS8	9058
PRKACA	9014
DYNLRB1	8978
TTC21B	8976
ATP5PO	8939
TCTN3	8893
TRAF3IP1	8892
CHCHD3	8882
NCOA6	8865
IFT88	8833
TTBK2	8817
PPARA	8725
CREB1	8716
IFT172	8689
PPRC1	8630
CNTRL	8628
EXOC3	8510
CEP72	8407
ATAT1	8386
MTX2	8351
GLUD1	8345
CARM1	8334
CRTC2	8332
PKD1	8286
ATP5MG	8267
IFT22	8229
CEP63	8212
CKAP5	8128
BBS7	8051
CEP192	7966
TFB1M	7771
SFI1	7760
ATP5MC1	7701
PRKAB2	7695
RAB11FIP3	7687
KIF24	7651
SCLT1	7550
IQCB1	7332
DCTN1	7179
PDE6D	6985
HAUS6	6964
IFT122	6894
CDK5RAP2	6570
IFT81	6556
CCT3	6496
MAPK12	6474
ACTR1A	6363
CEP57	6346
NDE1	6318
BBS4	6262
NR1D1	6211
PCM1	6109
NPHP4	6049
CRTC3	5970
NPHP1	5760
DYNLRB2	5575
ARL6	5467
HDAC3	5406
IFT46	5389
PRKAG2	5343
EXOC5	5304
ESRRA	5295
CEP164	5278
WDR35	5274
MAPK14	5180
CEP131	5065
BBS12	5031
CNGA4	4992
B9D1	4984
EXOC8	4947
GABPB1	4922
RXRA	4895
TTC8	4789
PLK4	4782
C2CD3	4732
IFT80	4658
KIF17	4620
HELZ2	4581
DYNC2I1	4566
IFT74	4513
B9D2	4467
TUBB	4460
IFT20	4364
PPP2R1A	4310
WDR19	4292
MARK4	4241
TUBA4A	4239
ARF4	4207
DYNLL1	4203
PPARGC1A	4184
CEP43	4180
DMAC2L	4148
TUBB2A	4122
TCTN2	4112
ODF2	4100
CYCS	4068
SIRT4	4051
GBF1	4003
POLRMT	3944
TUBB2B	3907
IFT27	3829
TUBA4B	3811
NEDD1	3777
ARL13B	3770
AKAP9	3759
EXOC6	3725
TNPO1	3709
KIFAP3	3614
CHD9	3604
ATP5F1C	3514
PLK1	3472
MTERF1	3421
TMEM11	3246
SDCCAG8	3232
DCTN2	3135
TFB2M	3131
SSTR3	3119
HAUS4	3083
CEP97	3061
FBF1	2999
MICOS10	2835
NEK2	2787
NCOA2	2754
ATP5PB	2748
PRKAG1	2584
BBS10	2495
TUBB4B	2340
CEP162	2333
TUBG1	2186
KIF3B	2165
SAMM50	2164
ATP5MC2	2152
TMEM67	2098
EXOC4	1981
EXOC2	1943
PKD2	1937
TGS1	1787
IFT43	1668
NPHP3	1657
TFAM	1637
CDK1	1360
NCOA1	1280
BBS5	1067
RAB11A	1050
TUBA1A	1018
ASAP1	956
SIRT5	923
ATP5MC3	732
CCP110	730
AHI1	506
IFT57	424
TWNK	368
CCT2	294
TBL1XR1	245
RPGRIP1L	203
TUBB6	150
ARL3	94
SSBP1	-51
DYNLT2B	-52
BBIP1	-103
MAPRE1	-157
TUBB4A	-357
NRF1	-364
TUBA8	-372
ATP5F1A	-385
CEP83	-755
BBS2	-799
IFT52	-886
MICOS13	-1040
DYNLT5	-1075
CEP78	-1096
TRIP11	-1118
SSNA1	-1130
CEP76	-1238
MKKS	-1435
CEP70	-1485
HAUS1	-1510
TMEM216	-1838
CEP89	-1998
CAMK4	-2240
BBS9	-2243
BBS1	-2253
CEP41	-2263
CYS1	-2266
ATP5F1D	-2304
DYNC2H1	-2372
SIRT3	-2452
HAUS3	-2507
PPARGC1B	-2589
CNGB1	-2670
ATP5PF	-2676
DYNC1I2	-2797
ALMS1	-3091
CEP135	-3106
DYNLT2	-3112
MEF2C	-3189
EXOC1	-3376
HSP90AA1	-3488
TUBA3D	-3545
TUBA1C	-3556
ATF2	-3617
MAPK11	-3828
POLG2	-3924
TUBB3	-4002
PERM1	-4059
GABPA	-4215
SOD2	-4248
TUBA3E	-4662
CHCHD6	-4681
PRKAA2	-4922
MTX1	-5013
HAUS2	-5154
ATP5ME	-5164
SMO	-5257
KIF3A	-5617
PRKAG3	-5700
NINL	-5777
DYNC2LI1	-5921
KIF3C	-5979
SMARCD3	-6048
TUBA1B	-6340
CC2D2A	-6413
INPP5E	-6515
TUBB1	-6519
ACSS2	-7103
ATP5F1E	-7155
TUBA3C	-7269
TUBAL3	-7278
IDH2	-7979
PRKAR2B	-7999
RHO	-8208
TUBB8	-8942

---

REACTOME_PTEN_REGULATION

REACTOME_PTEN_REGULATION

	1079
set	REACTOME_PTEN_REGULATION
setSize	135
pANOVA	7.19e-09
s.dist	0.288
p.adjustANOVA	2.62e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
LAMTOR3	11769
AGO1	11345
MTA1	11188
PSMB4	11076
GATAD2A	11072
MTOR	11011
USP7	10931
PSMD4	10893
CHD3	10888
PSMD13	10870
PSMA2	10707
PSMC6	10418
CHD4	10037
PSMD3	9979
OTUD3	9950
PSMD7	9804
AKT1	9802
AGO2	9717
PSMC4	9692
RPTOR	9678

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
LAMTOR3	11769
AGO1	11345
MTA1	11188
PSMB4	11076
GATAD2A	11072
MTOR	11011
USP7	10931
PSMD4	10893
CHD3	10888
PSMD13	10870
PSMA2	10707
PSMC6	10418
CHD4	10037
PSMD3	9979
OTUD3	9950
PSMD7	9804
AKT1	9802
AGO2	9717
PSMC4	9692
RPTOR	9678
PSMD2	9598
LAMTOR1	9581
PSMB5	9461
TNRC6C	9415
PSMF1	9002
LAMTOR4	8940
WWP2	8894
SNAI1	8809
MAF1	8573
ATN1	8569
PSMB7	8555
RCOR1	8525
PSMA4	8487
AKT2	8422
PML	8234
HDAC5	8138
KDM1A	8061
PSMB1	7978
PSMA6	7971
RHEB	7765
CSNK2A1	7758
PSME2	7675
TNRC6A	7634
MBD3	7608
PSMD1	7564
MAPK3	7526
RPS27A	7499
PSME1	7470
MTA3	7374
PSMA3	7039
PSMA1	6977
PSMD6	6942
PSMB3	6665
PHC2	6654
PSMD11	6649
PSMD12	6422
PSMB6	6370
PSMD5	6295
PSME3	6289
RING1	6185
TNRC6B	6144
CBX4	6103
HDAC1	6062
CSNK2A2	5953
PSMD9	5939
MAPK1	5826
USP13	5634
JUN	5629
SUZ12	5592
CSNK2B	5559
HDAC3	5406
PSMB2	5390
UBC	5385
BMI1	5313
CBX8	5208
PSMA7	5054
PHC3	4783
SCMH1	4529
TRIM27	4525
PSMA8	4378
PTEN	4078
PSMC2	4047
PSMB10	3971
GATAD2B	3962
RBBP4	3878
PHC1	3804
RNF146	3594
TP53	3499
MTA2	3431
AGO3	3420
PSMC3	3323
PSMC1	3148
PSME4	3137
PSMC5	3065
CBX2	2819
HDAC7	2721
PSMB8	2300
RRAGA	2063
PSMD14	1903
EGR1	1747
PSMB11	1723
TNKS	1634
MOV10	1158
NEDD4	1072
MLST8	854
EED	774
CBX6	622
AKT3	516
RRAGD	-414
MKRN1	-634
EZH2	-873
RRAGC	-2062
UBA52	-2237
UBB	-2335
RNF2	-2391
NR2E1	-2530
PSMB9	-2938
SNAI2	-3097
REST	-3392
LAMTOR5	-3417
SLC38A9	-3577
ATF2	-3617
PSMA5	-4331
SALL4	-4508
TNKS2	-4742
STUB1	-4920
PSMD8	-5050
AGO4	-5113
PREX2	-5316
FRK	-6269
MECOM	-7108
LAMTOR2	-7256
HDAC2	-7451
SEM1	-7461
PPARG	-7622

---

REACTOME_TRNA_PROCESSING

REACTOME_TRNA_PROCESSING

	1147
set	REACTOME_TRNA_PROCESSING
setSize	105
pANOVA	8.46e-09
s.dist	0.325
p.adjustANOVA	3.02e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TRMT44	12008
QTRT1	11266
ADAT1	11250
ADAT3	11056
RAE1	10890
WDR4	10542
NUP210	10455
CPSF1	10403
TRMT61B	10333
NUP62	10167
NUP85	10023
NUP54	9855
CTU2	9752
CPSF4	9551
URM1	9548
NUP88	9522
NUP133	9347
ELAC2	9315
XPOT	9078
TRNT1	9043

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TRMT44	12008
QTRT1	11266
ADAT1	11250
ADAT3	11056
RAE1	10890
WDR4	10542
NUP210	10455
CPSF1	10403
TRMT61B	10333
NUP62	10167
NUP85	10023
NUP54	9855
CTU2	9752
CPSF4	9551
URM1	9548
NUP88	9522
NUP133	9347
ELAC2	9315
XPOT	9078
TRNT1	9043
TRMT61A	8947
NSUN2	8782
C2orf49	8730
CTU1	8513
NUP93	8494
TSEN2	8255
POM121	8233
NUP50	8160
AAAS	8159
NUP58	8140
CLP1	8113
QTRT2	8039
NUP98	7826
DUS2	7681
RPP38	7255
ALKBH8	7159
TRMT1	6976
TPRKB	6876
NUP37	6708
TRMT112	6663
NSUN6	6636
TPR	6489
RPP30	6434
NUP160	6322
POP4	6127
RPP40	5952
SEH1L	5744
TYW5	5534
NUP42	5371
RPPH1	5338
TRMT10C	5266
RAN	5055
GTPBP3	4908
OSGEP	4906
RANBP2	4890
SEC13	4854
NUP214	4833
RPP14	4650
POP7	4640
TRIT1	4606
PUS3	4536
ZBTB8OS	3998
FAM98B	3649
MTO1	3611
TRDMT1	3601
LCMT2	3542
THADA	3528
THG1L	3503
TRMT11	3414
TRMT13	3399
NUP107	3276
NDC1	3079
POP1	3042
METTL1	3004
PUS1	2856
NUP188	2493
CDKAL1	2407
NUP35	2378
TYW3	2212
POM121C	2036
TRMU	1601
DDX1	1418
TSEN54	1389
RPP25	1073
TSEN15	1043
RPP21	802
PUS7	720
TSEN34	707
TRMT6	631
NUP43	561
NUP205	331
TP53RK	-391
RTCB	-1103
PRORP	-1114
TRMT10A	-1906
POP5	-2273
NUP153	-2541
TYW1	-2556
RTRAF	-2697
TRMT9B	-3103
NUP155	-3213
EPRS1	-3323
TRMT12	-4103
TRMT5	-4627
ADAT2	-5425

---

REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION

REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION

	437
set	REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION
setSize	138
pANOVA	8.71e-09
s.dist	0.284
p.adjustANOVA	3.04e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2BC15	11524
H4C5	11447
POLR2E	11395
H2BC6	11322
MTA1	11188
GATAD2A	11072
CHD3	10888
TET3	10875
H2AZ1	10867
ERCC3	10866
SAP30L	10745
TAF1C	10187
CHD4	10037
MYO1C	9714
TTF1	9582
H2AC4	9477
EP300	9390
TDG	9316
KAT2B	9295
SAP130	9133

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2BC15	11524.0
H4C5	11447.0
POLR2E	11395.0
H2BC6	11322.0
MTA1	11188.0
GATAD2A	11072.0
CHD3	10888.0
TET3	10875.0
H2AZ1	10867.0
ERCC3	10866.0
SAP30L	10745.0
TAF1C	10187.0
CHD4	10037.0
MYO1C	9714.0
TTF1	9582.0
H2AC4	9477.0
EP300	9390.0
TDG	9316.0
KAT2B	9295.0
SAP130	9133.0
H4C6	9077.0
BAZ1B	9069.0
TAF1A	8920.0
H3C11	8908.0
H2BC10	8901.0
POLR1F	8883.0
TAF1B	8745.0
DEK	8586.0
KAT2A	8511.0
CCNH	8458.0
POLR2H	8450.0
MYBBP1A	8279.0
H2AC6	8277.0
H4C11	8241.0
H4C13	8117.0
H4C1	8017.0
DNMT3A	7952.0
H2AC8	7728.0
MBD3	7608.0
H2BC4	7539.0
H3C1	7395.0
MTA3	7374.0
SAP30	7289.0
H2BC9	7228.5
H3C7	7228.5
EHMT2	7223.0
H4C8	7058.0
SF3B1	6993.0
POLR1A	6880.0
CBX3	6860.0
SAP18	6685.0
SUDS3	6677.0
H3C10	6652.0
H2BC8	6334.0
H2BC12	6220.0
JARID2	6167.0
SMARCA5	6154.0
CDK7	6114.0
HDAC1	6062.0
ACTB	6053.0
POLR1D	5990.0
H3C4	5911.0
POLR1H	5816.0
GSK3B	5797.0
SIN3A	5710.0
TBP	5601.0
SUZ12	5592.0
GTF2H3	5566.0
SIN3B	5452.0
H4C3	5297.0
TET2	5172.0
H2AJ	5141.0
ERCC2	5135.0
GTF2H1	4840.0
BAZ2A	4803.0
POLR2F	4630.0
POLR1B	4353.0
TAF1D	4272.0
RRP8	4166.0
H4C2	3987.0
GATAD2B	3962.0
RBBP4	3878.0
GTF2H5	3727.0
H4C4	3596.0
AEBP2	3547.0
H3C8	3521.0
MTA2	3431.0
H2AC20	3382.0
POLR1E	3283.0
H3-3B	3055.0
H2AC18	2954.5
H2AC19	2954.5
ERCC6	2904.0
H2AC7	2792.5
H2BC7	2792.5
H2BC21	2718.0
MBD2	2593.0
UBTF	2553.0
ARID4B	2538.0
H3-3A	2262.0
H2BC5	2100.0
GTF2H4	2092.0
H2BC17	1857.0
H2BC13	1834.0
H3C2	1828.0
TET1	1791.0
PHF1	1727.0
SIRT1	1473.0
H2BC11	1286.0
POLR1G	916.0
EED	774.0
DDX21	657.0
UHRF1	636.0
POLR1C	-257.0
H4C9	-276.0
MNAT1	-336.0
H2AX	-614.0
EZH2	-873.0
DNMT1	-1138.0
POLR2L	-1678.0
MTF2	-2142.0
DNMT3L	-2675.0
H2BC26	-2895.0
SAP30BP	-2932.0
DNMT3B	-3433.0
H2AZ2	-3800.0
POLR2K	-3852.0
H2BC1	-4453.0
H3C6	-4925.0
H2AC14	-5418.0
H2BC3	-5733.0
H4C16	-5871.0
PHF19	-5923.0
H3C3	-6688.0
H2BC14	-7035.0
H4C12	-7199.0
HDAC2	-7451.0
H3C12	-7844.0

---

REACTOME_GENE_SILENCING_BY_RNA

REACTOME_GENE_SILENCING_BY_RNA

	426
set	REACTOME_GENE_SILENCING_BY_RNA
setSize	133
pANOVA	1.1e-08
s.dist	0.287
p.adjustANOVA	3.76e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
POLR2J	11816
H2BC15	11524
PIWIL1	11467
H4C5	11447
TDRD12	11422
POLR2A	11407
POLR2E	11395
AGO1	11345
H2BC6	11322
RAE1	10890
H2AZ1	10867
MIR23B	10726
PLD6	10672
NUP210	10455
POLR2B	10306
NUP62	10167
TSN	10141
NUP85	10023
NUP54	9855
AGO2	9717

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
POLR2J	11816.0
H2BC15	11524.0
PIWIL1	11467.0
H4C5	11447.0
TDRD12	11422.0
POLR2A	11407.0
POLR2E	11395.0
AGO1	11345.0
H2BC6	11322.0
RAE1	10890.0
H2AZ1	10867.0
MIR23B	10726.0
PLD6	10672.0
NUP210	10455.0
POLR2B	10306.0
NUP62	10167.0
TSN	10141.0
NUP85	10023.0
NUP54	9855.0
AGO2	9717.0
NUP88	9522.0
H2AC4	9477.0
TNRC6C	9415.0
NUP133	9347.0
ELAC2	9315.0
H4C6	9077.0
DROSHA	9004.0
H3C11	8908.0
H2BC10	8901.0
PIWIL2	8766.0
NUP93	8494.0
POLR2H	8450.0
BCDIN3D	8393.0
H2AC6	8277.0
H4C11	8241.0
POM121	8233.0
TSNAX	8162.0
NUP50	8160.0
AAAS	8159.0
DICER1	8142.0
NUP58	8140.0
H4C13	8117.0
H4C1	8017.0
NUP98	7826.0
H2AC8	7728.0
TNRC6A	7634.0
H2BC4	7539.0
H3C1	7395.0
H2BC9	7228.5
H3C7	7228.5
H4C8	7058.0
PRKRA	6815.0
NUP37	6708.0
H3C10	6652.0
TPR	6489.0
IPO8	6399.0
H2BC8	6334.0
NUP160	6322.0
H2BC12	6220.0
TNRC6B	6144.0
H3C4	5911.0
SEH1L	5744.0
ASZ1	5444.0
NUP42	5371.0
H4C3	5297.0
POLR2I	5214.0
H2AJ	5141.0
RAN	5055.0
POLR2G	4982.0
RANBP2	4890.0
SEC13	4854.0
NUP214	4833.0
DGCR8	4785.0
POLR2F	4630.0
ANG	4527.0
MAEL	4476.0
H4C2	3987.0
XPO5	3818.0
H4C4	3596.0
H3C8	3521.0
AGO3	3420.0
H2AC20	3382.0
NUP107	3276.0
POLR2D	3258.0
NDC1	3079.0
H3-3B	3055.0
H2AC18	2954.5
H2AC19	2954.5
H2AC7	2792.5
H2BC7	2792.5
H2BC21	2718.0
TDRD6	2520.0
NUP188	2493.0
NUP35	2378.0
H3-3A	2262.0
H2BC5	2100.0
POM121C	2036.0
H2BC17	1857.0
H2BC13	1834.0
H3C2	1828.0
MOV10L1	1789.0
TDRKH	1761.0
HENMT1	1430.0
H2BC11	1286.0
NUP43	561.0
NUP205	331.0
H4C9	-276.0
PIWIL4	-571.0
H2AX	-614.0
POLR2L	-1678.0
FKBP6	-1693.0
TARBP2	-1981.0
DDX4	-2114.0
NUP153	-2541.0
H2BC26	-2895.0
MYBL1	-3047.0
NUP155	-3213.0
HSP90AA1	-3488.0
TDRD1	-3748.0
H2AZ2	-3800.0
POLR2K	-3852.0
TDRD9	-4274.0
H2BC1	-4453.0
H3C6	-4925.0
AGO4	-5113.0
H2AC14	-5418.0
H2BC3	-5733.0
H4C16	-5871.0
POLR2C	-6018.0
H3C3	-6688.0
H2BC14	-7035.0
H4C12	-7199.0
H3C12	-7844.0

---

REACTOME_MITOTIC_SPINDLE_CHECKPOINT

REACTOME_MITOTIC_SPINDLE_CHECKPOINT

	1119
set	REACTOME_MITOTIC_SPINDLE_CHECKPOINT
setSize	109
pANOVA	1.14e-08
s.dist	0.316
p.adjustANOVA	3.82e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RANGAP1	11517
RCC2	11484
INCENP	11431
DYNLL2	11413
PPP2R1B	10998
PPP2R5D	10733
AHCTF1	10728
DYNC1H1	10679
CDC23	10475
ANAPC15	10466
CENPN	10448
PAFAH1B1	10395
CDCA8	10170
DYNC1LI2	10120
SGO1	10062
NUP85	10023
CENPF	10012
NSL1	9660
ANAPC1	9651
CENPS	9547

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RANGAP1	11517
RCC2	11484
INCENP	11431
DYNLL2	11413
PPP2R1B	10998
PPP2R5D	10733
AHCTF1	10728
DYNC1H1	10679
CDC23	10475
ANAPC15	10466
CENPN	10448
PAFAH1B1	10395
CDCA8	10170
DYNC1LI2	10120
SGO1	10062
NUP85	10023
CENPF	10012
NSL1	9660
ANAPC1	9651
CENPS	9547
BUB1B	9388
NUP133	9347
NUDC	9330
CLASP1	9232
CENPP	9001
ZWILCH	8932
XPO1	8891
NDEL1	8779
CLIP1	8310
PMF1	8197
CKAP5	8128
ANAPC16	8064
NUP98	7826
KNTC1	7772
ANAPC4	7652
ANAPC5	7558
CDC27	7198
MAD1L1	7020
DSN1	6888
KIF18A	6886
CDC16	6748
NUP37	6708
RPS27	6477
ANAPC10	6338
NUP160	6322
NDE1	6318
CENPM	6069
CENPL	6013
ANAPC11	5794
SEH1L	5744
CENPE	5720
CDC26	5692
CENPC	5654
CENPU	5624
CENPK	5296
DYNC1LI1	5132
CENPQ	5131
PPP2R5C	5016
CLASP2	4967
RANBP2	4890
SEC13	4854
B9D2	4467
PPP2R1A	4310
KIF2A	4282
SGO2	4264
KIF2B	4249
DYNLL1	4203
BUB3	3920
BUB1	3874
CENPO	3792
ANAPC7	3782
ZWINT	3720
TAOK1	3609
PLK1	3472
UBE2E1	3470
NUP107	3276
MIS12	2770
PPP1CC	2315
KNL1	2176
UBE2S	1865
PPP2R5A	1572
SKA2	1570
NDC80	1352
NUF2	899
AURKB	823
CDC20	611
NUP43	561
PPP2CB	497
PPP2R5B	256
PPP2R5E	-53
MAPRE1	-157
KIF2C	-1021
ANAPC2	-1206
CENPA	-1250
UBE2D1	-1471
ITGB3BP	-1974
CENPT	-2031
PPP2CA	-2084
MAD2L1	-2478
ZW10	-2497
CENPH	-2615
DYNC1I2	-2797
UBE2C	-3845
SPC25	-4088
SKA1	-4482
BIRC5	-4539
DYNC1I1	-5334
SPDL1	-5533
SPC24	-7608

---

REACTOME_MITOTIC_PROMETAPHASE

REACTOME_MITOTIC_PROMETAPHASE

	1094
set	REACTOME_MITOTIC_PROMETAPHASE
setSize	194
pANOVA	1.37e-08
s.dist	0.236
p.adjustANOVA	4.5e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CSNK1D	11871
CEP250	11821
RANGAP1	11517
RCC2	11484
INCENP	11431
DYNLL2	11413
PCNT	11389
NUMA1	11246
TUBGCP3	11180
PPP2R1B	10998
NCAPD2	10988
DCTN3	10909
PPP2R5D	10733
AHCTF1	10728
DYNC1H1	10679
YWHAE	10677
HAUS5	10645
CENPN	10448
PAFAH1B1	10395
CEP152	10291

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CSNK1D	11871
CEP250	11821
RANGAP1	11517
RCC2	11484
INCENP	11431
DYNLL2	11413
PCNT	11389
NUMA1	11246
TUBGCP3	11180
PPP2R1B	10998
NCAPD2	10988
DCTN3	10909
PPP2R5D	10733
AHCTF1	10728
DYNC1H1	10679
YWHAE	10677
HAUS5	10645
CENPN	10448
PAFAH1B1	10395
CEP152	10291
CDCA8	10170
DYNC1LI2	10120
SGO1	10062
NUP85	10023
CENPF	10012
TUBGCP2	9732
NSL1	9660
YWHAG	9563
CENPS	9547
CENPJ	9539
CSNK1E	9526
TUBGCP6	9408
BUB1B	9388
MZT2A	9358
NUP133	9347
NUDC	9330
CEP290	9276
CLASP1	9232
HAUS8	9058
PRKACA	9014
CENPP	9001
ZWILCH	8932
XPO1	8891
STAG1	8828
NDEL1	8779
CNTRL	8628
SMC2	8434
CEP72	8407
CLIP1	8310
SMC3	8217
CEP63	8212
PMF1	8197
CDCA5	8184
CKAP5	8128
CEP192	7966
TUBG2	7860
NUP98	7826
KNTC1	7772
SFI1	7760
CSNK2A1	7758
DCTN1	7179
NEK6	7102
MAD1L1	7020
HAUS6	6964
DSN1	6888
KIF18A	6886
NUP37	6708
CDK5RAP2	6570
RPS27	6477
PDS5A	6446
ACTR1A	6363
CEP57	6346
NUP160	6322
NDE1	6318
PCM1	6109
CENPM	6069
CENPL	6013
CSNK2A2	5953
SEH1L	5744
CENPE	5720
CENPC	5654
CENPU	5624
CSNK2B	5559
CENPK	5296
CEP164	5278
DYNC1LI1	5132
CENPQ	5131
CEP131	5065
PPP2R5C	5016
EML4	4980
CLASP2	4967
RANBP2	4890
SEC13	4854
PLK4	4782
WAPL	4638
B9D2	4467
TUBB	4460
PPP2R1A	4310
KIF2A	4282
SGO2	4264
KIF2B	4249
TUBA4A	4239
DYNLL1	4203
CEP43	4180
TUBB2A	4122
ODF2	4100
BUB3	3920
TUBB2B	3907
BUB1	3874
TUBA4B	3811
CENPO	3792
NEDD1	3777
AKAP9	3759
ZWINT	3720
TAOK1	3609
TUBGCP4	3597
PLK1	3472
NUP107	3276
SDCCAG8	3232
DCTN2	3135
HAUS4	3083
NEK2	2787
MIS12	2770
TUBB4B	2340
PPP1CC	2315
TUBG1	2186
KNL1	2176
CCNB1	2131
PPP2R5A	1572
SKA2	1570
CDK1	1360
NDC80	1352
TUBA1A	1018
NUF2	899
AURKB	823
CCP110	730
NEK9	629
CDC20	611
PDS5B	610
NUP43	561
PPP2CB	497
NEK7	489
SMC4	404
PPP2R5B	256
TUBB6	150
CCNB2	97
PPP2R5E	-53
MAPRE1	-157
TUBB4A	-357
TUBA8	-372
NME7	-869
KIF2C	-1021
CEP78	-1096
SSNA1	-1130
CEP76	-1238
CENPA	-1250
CEP70	-1485
HAUS1	-1510
ITGB3BP	-1974
CENPT	-2031
PPP2CA	-2084
CEP41	-2263
NCAPG	-2420
MAD2L1	-2478
ZW10	-2497
HAUS3	-2507
CENPH	-2615
DYNC1I2	-2797
TUBGCP5	-2825
ALMS1	-3091
CEP135	-3106
RAD21	-3318
HSP90AA1	-3488
TUBA3D	-3545
TUBA1C	-3556
TUBB3	-4002
SPC25	-4088
SKA1	-4482
BIRC5	-4539
TUBA3E	-4662
NCAPH	-5000
HAUS2	-5154
DYNC1I1	-5334
SPDL1	-5533
NINL	-5777
TUBA1B	-6340
TUBB1	-6519
MZT1	-6533
TUBA3C	-7269
TUBAL3	-7278
SPC24	-7608
PRKAR2B	-7999
MZT2B	-8863
TUBB8	-8942

---

Here is the session info with all the versions of packages used.

sessionInfo()

## R version 4.3.2 (2023-10-31)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.3 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3 
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so;  LAPACK version 3.10.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Etc/UTC
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.3.3                                      
##  [2] GGally_2.2.0                                       
##  [3] ggplot2_3.4.4                                      
##  [4] reshape2_1.4.4                                     
##  [5] gtools_3.9.5                                       
##  [6] tibble_3.2.1                                       
##  [7] dplyr_1.1.4                                        
##  [8] echarts4r_0.4.5                                    
##  [9] png_0.1-8                                          
## [10] gridExtra_2.3                                      
## [11] missMethyl_1.36.0                                  
## [12] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.1 
## [13] beeswarm_0.4.0                                     
## [14] kableExtra_1.3.4                                   
## [15] gplots_3.1.3                                       
## [16] mitch_1.15.0                                       
## [17] tictoc_1.2                                         
## [18] HGNChelper_0.8.1                                   
## [19] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [20] IlluminaHumanMethylation450kmanifest_0.4.0         
## [21] minfi_1.48.0                                       
## [22] bumphunter_1.44.0                                  
## [23] locfit_1.5-9.8                                     
## [24] iterators_1.0.14                                   
## [25] foreach_1.5.2                                      
## [26] Biostrings_2.70.1                                  
## [27] XVector_0.42.0                                     
## [28] SummarizedExperiment_1.32.0                        
## [29] Biobase_2.62.0                                     
## [30] MatrixGenerics_1.14.0                              
## [31] matrixStats_1.2.0                                  
## [32] GenomicRanges_1.54.1                               
## [33] GenomeInfoDb_1.38.2                                
## [34] IRanges_2.36.0                                     
## [35] S4Vectors_0.40.2                                   
## [36] BiocGenerics_0.48.1                                
## [37] eulerr_7.0.0                                       
## [38] limma_3.58.1                                       
## 
## loaded via a namespace (and not attached):
##   [1] splines_4.3.2             later_1.3.2              
##   [3] BiocIO_1.12.0             bitops_1.0-7             
##   [5] filelock_1.0.3            preprocessCore_1.64.0    
##   [7] XML_3.99-0.16             lifecycle_1.0.4          
##   [9] lattice_0.22-5            MASS_7.3-60              
##  [11] base64_2.0.1              scrime_1.3.5             
##  [13] magrittr_2.0.3            sass_0.4.8               
##  [15] rmarkdown_2.25            jquerylib_0.1.4          
##  [17] yaml_2.3.8                httpuv_1.6.13            
##  [19] doRNG_1.8.6               askpass_1.2.0            
##  [21] DBI_1.1.3                 RColorBrewer_1.1-3       
##  [23] abind_1.4-5               zlibbioc_1.48.0          
##  [25] rvest_1.0.3               quadprog_1.5-8           
##  [27] purrr_1.0.2               RCurl_1.98-1.13          
##  [29] rappdirs_0.3.3            GenomeInfoDbData_1.2.11  
##  [31] genefilter_1.84.0         annotate_1.80.0          
##  [33] svglite_2.1.3             DelayedMatrixStats_1.24.0
##  [35] codetools_0.2-19          DelayedArray_0.28.0      
##  [37] xml2_1.3.6                tidyselect_1.2.0         
##  [39] beanplot_1.3.1            BiocFileCache_2.10.1     
##  [41] webshot_0.5.5             illuminaio_0.44.0        
##  [43] GenomicAlignments_1.38.0  jsonlite_1.8.8           
##  [45] multtest_2.58.0           ellipsis_0.3.2           
##  [47] survival_3.5-7            systemfonts_1.0.5        
##  [49] tools_4.3.2               progress_1.2.3           
##  [51] Rcpp_1.0.11               glue_1.6.2               
##  [53] SparseArray_1.2.2         xfun_0.41                
##  [55] HDF5Array_1.30.0          withr_2.5.2              
##  [57] fastmap_1.1.1             rhdf5filters_1.14.1      
##  [59] fansi_1.0.6               openssl_2.1.1            
##  [61] caTools_1.18.2            digest_0.6.33            
##  [63] R6_2.5.1                  mime_0.12                
##  [65] colorspace_2.1-0          biomaRt_2.58.0           
##  [67] RSQLite_2.3.4             utf8_1.2.4               
##  [69] tidyr_1.3.0               generics_0.1.3           
##  [71] data.table_1.14.10        rtracklayer_1.62.0       
##  [73] prettyunits_1.2.0         httr_1.4.7               
##  [75] htmlwidgets_1.6.4         S4Arrays_1.2.0           
##  [77] ggstats_0.5.1             pkgconfig_2.0.3          
##  [79] gtable_0.3.4              blob_1.2.4               
##  [81] siggenes_1.76.0           htmltools_0.5.7          
##  [83] scales_1.3.0              rstudioapi_0.15.0        
##  [85] knitr_1.45                tzdb_0.4.0               
##  [87] rjson_0.2.21              nlme_3.1-163             
##  [89] curl_5.2.0                org.Hs.eg.db_3.18.0      
##  [91] cachem_1.0.8              rhdf5_2.46.1             
##  [93] stringr_1.5.1             KernSmooth_2.23-22       
##  [95] AnnotationDbi_1.64.1      restfulr_0.0.15          
##  [97] GEOquery_2.70.0           pillar_1.9.0             
##  [99] grid_4.3.2                reshape_0.8.9            
## [101] vctrs_0.6.5               promises_1.2.1           
## [103] dbplyr_2.4.0              xtable_1.8-4             
## [105] evaluate_0.23             readr_2.1.4              
## [107] GenomicFeatures_1.54.1    cli_3.6.2                
## [109] compiler_4.3.2            Rsamtools_2.18.0         
## [111] rlang_1.1.2               crayon_1.5.2             
## [113] rngtools_1.5.2            nor1mix_1.3-2            
## [115] mclust_6.0.1              plyr_1.8.9               
## [117] stringi_1.8.3             viridisLite_0.4.2        
## [119] BiocParallel_1.36.0       munsell_0.5.0            
## [121] Matrix_1.6-1.1            hms_1.1.3                
## [123] sparseMatrixStats_1.14.0  bit64_4.0.5              
## [125] Rhdf5lib_1.24.1           KEGGREST_1.42.0          
## [127] statmod_1.5.0             shiny_1.8.0              
## [129] highr_0.10                memoise_2.0.1            
## [131] bslib_0.6.1               bit_4.0.5

END of report