Mitch Report

date generated: 2024-01-18

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch

	x
A1BG	-0.0327014
A1BG-AS1	-0.0318216
A1CF	0.0307954
A2M	-0.0163850
A2M-AS1	-0.3148700
A2ML1	0.1009085

Here are some metrics about the input data profile:

Profiling data metrics

	Profile metrics
num_genesets	1654
num_genes_in_profile	22007
duplicated_genes_present	0
num_profile_genes_in_sets	10383
num_profile_genes_not_in_sets	11624

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets: c2.cp.reactome.v2023.1.Hs.symbols.gmt

Gene set metrics

	Gene sets metrics
num_genesets	1654
num_genesets_excluded	365
num_genesets_included	1289

Differential pathway expression

Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

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## in kable. kableExtra can customize either HTML or LaTeX outputs. See
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set	setSize	pANOVA	s.dist	p.adjustANOVA
REACTOME OLFACTORY SIGNALING PATHWAY	348	1.28e-11	-0.2110	2.10e-08
REACTOME SENSORY PERCEPTION	555	2.89e-09	-0.1470	2.37e-06
REACTOME TRANSLATION	278	4.71e-07	0.1760	2.58e-04
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	105	1.25e-06	0.2740	5.12e-04
REACTOME NONSENSE MEDIATED DECAY NMD	107	2.40e-06	0.2640	7.90e-04
REACTOME METABOLISM OF RNA	675	3.89e-06	0.1040	1.07e-03
REACTOME EUKARYOTIC TRANSLATION ELONGATION	87	5.35e-06	0.2820	1.17e-03
REACTOME EUKARYOTIC TRANSLATION INITIATION	110	5.70e-06	0.2500	1.17e-03
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS	161	7.28e-06	0.2050	1.33e-03
REACTOME SELENOAMINO ACID METABOLISM	108	3.62e-05	0.2300	5.94e-03
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY	94	4.18e-05	0.2440	6.24e-03
REACTOME SIGNALING BY ROBO RECEPTORS	206	6.10e-05	0.1620	8.34e-03
REACTOME SENSORY PERCEPTION OF TASTE	47	8.98e-05	-0.3300	1.13e-02
REACTOME RRNA PROCESSING	192	1.14e-04	0.1610	1.34e-02
REACTOME SIGNALING BY FGFR	85	1.64e-04	0.2360	1.80e-02
REACTOME RNA POLYMERASE II TRANSCRIPTION	1336	2.04e-04	0.0605	2.10e-02
REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	39	2.93e-04	-0.3350	2.83e-02
REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING	32	3.41e-04	0.3660	3.11e-02
REACTOME SIGNALING BY FGFR2	72	5.27e-04	0.2360	4.56e-02
REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	353	6.35e-04	0.1060	5.22e-02
REACTOME CELLULAR RESPONSE TO STARVATION	147	1.20e-03	0.1550	9.09e-02
REACTOME SIGNALING BY FGFR1	49	1.27e-03	0.2660	9.09e-02
REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	15	1.27e-03	0.4800	9.09e-02
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	53	1.37e-03	0.2540	9.41e-02
REACTOME STRIATED MUSCLE CONTRACTION	35	1.90e-03	0.3030	1.24e-01
REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING	33	2.02e-03	0.3100	1.24e-01
REACTOME ERKS ARE INACTIVATED	13	2.03e-03	0.4940	1.24e-01
REACTOME FGFR2 LIGAND BINDING AND ACTIVATION	19	2.11e-03	0.4070	1.24e-01
REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING	30	2.56e-03	0.3180	1.45e-01
REACTOME GLUCURONIDATION	23	2.83e-03	-0.3600	1.54e-01
REACTOME DEVELOPMENTAL BIOLOGY	1115	3.17e-03	0.0524	1.54e-01
REACTOME CELLULAR RESPONSES TO STIMULI	779	3.29e-03	0.0619	1.54e-01
REACTOME INFLUENZA INFECTION	149	3.32e-03	0.1390	1.54e-01
REACTOME PI 3K CASCADE FGFR1	21	3.38e-03	0.3690	1.54e-01
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY	33	3.43e-03	0.2940	1.54e-01
REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING	28	3.59e-03	0.3180	1.54e-01
REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION	32	3.61e-03	0.2970	1.54e-01
REACTOME MAPK FAMILY SIGNALING CASCADES	314	3.66e-03	0.0954	1.54e-01
REACTOME FRS MEDIATED FGFR1 SIGNALING	23	3.66e-03	0.3500	1.54e-01
REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	59	3.97e-03	0.2170	1.63e-01
REACTOME SIGNALING BY FGFR4	40	4.16e-03	0.2620	1.67e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1	31	5.00e-03	0.2910	1.93e-01
REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM	23	5.05e-03	0.3380	1.93e-01
REACTOME SIGNALING BY NTRKS	132	5.35e-03	0.1400	2.00e-01
REACTOME SHC MEDIATED CASCADE FGFR1	21	6.23e-03	0.3450	2.27e-01
REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING	25	6.88e-03	0.3120	2.46e-01
REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS	8	7.05e-03	0.5500	2.46e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2	17	7.59e-03	0.3740	2.60e-01
REACTOME NEGATIVE REGULATION OF MAPK PATHWAY	41	7.79e-03	0.2400	2.61e-01
REACTOME FGFR1C LIGAND BINDING AND ACTIVATION	11	8.20e-03	0.4600	2.69e-01

---

Results (complete table)

Click HERE to show results for all gene sets

Complete results

set	setSize	pANOVA	s.dist	p.adjustANOVA
REACTOME OLFACTORY SIGNALING PATHWAY	348	1.28e-11	-0.211000	2.10e-08
REACTOME SENSORY PERCEPTION	555	2.89e-09	-0.147000	2.37e-06
REACTOME TRANSLATION	278	4.71e-07	0.176000	2.58e-04
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	105	1.25e-06	0.274000	5.12e-04
REACTOME NONSENSE MEDIATED DECAY NMD	107	2.40e-06	0.264000	7.90e-04
REACTOME METABOLISM OF RNA	675	3.89e-06	0.104000	1.07e-03
REACTOME EUKARYOTIC TRANSLATION ELONGATION	87	5.35e-06	0.282000	1.17e-03
REACTOME EUKARYOTIC TRANSLATION INITIATION	110	5.70e-06	0.250000	1.17e-03
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS	161	7.28e-06	0.205000	1.33e-03
REACTOME SELENOAMINO ACID METABOLISM	108	3.62e-05	0.230000	5.94e-03
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY	94	4.18e-05	0.244000	6.24e-03
REACTOME SIGNALING BY ROBO RECEPTORS	206	6.10e-05	0.162000	8.34e-03
REACTOME SENSORY PERCEPTION OF TASTE	47	8.98e-05	-0.330000	1.13e-02
REACTOME RRNA PROCESSING	192	1.14e-04	0.161000	1.34e-02
REACTOME SIGNALING BY FGFR	85	1.64e-04	0.236000	1.80e-02
REACTOME RNA POLYMERASE II TRANSCRIPTION	1336	2.04e-04	0.060500	2.10e-02
REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	39	2.93e-04	-0.335000	2.83e-02
REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING	32	3.41e-04	0.366000	3.11e-02
REACTOME SIGNALING BY FGFR2	72	5.27e-04	0.236000	4.56e-02
REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	353	6.35e-04	0.106000	5.22e-02
REACTOME CELLULAR RESPONSE TO STARVATION	147	1.20e-03	0.155000	9.09e-02
REACTOME SIGNALING BY FGFR1	49	1.27e-03	0.266000	9.09e-02
REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	15	1.27e-03	0.480000	9.09e-02
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	53	1.37e-03	0.254000	9.41e-02
REACTOME STRIATED MUSCLE CONTRACTION	35	1.90e-03	0.303000	1.24e-01
REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING	33	2.02e-03	0.310000	1.24e-01
REACTOME ERKS ARE INACTIVATED	13	2.03e-03	0.494000	1.24e-01
REACTOME FGFR2 LIGAND BINDING AND ACTIVATION	19	2.11e-03	0.407000	1.24e-01
REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING	30	2.56e-03	0.318000	1.45e-01
REACTOME GLUCURONIDATION	23	2.83e-03	-0.360000	1.54e-01
REACTOME DEVELOPMENTAL BIOLOGY	1115	3.17e-03	0.052400	1.54e-01
REACTOME CELLULAR RESPONSES TO STIMULI	779	3.29e-03	0.061900	1.54e-01
REACTOME INFLUENZA INFECTION	149	3.32e-03	0.139000	1.54e-01
REACTOME PI 3K CASCADE FGFR1	21	3.38e-03	0.369000	1.54e-01
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY	33	3.43e-03	0.294000	1.54e-01
REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING	28	3.59e-03	0.318000	1.54e-01
REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION	32	3.61e-03	0.297000	1.54e-01
REACTOME MAPK FAMILY SIGNALING CASCADES	314	3.66e-03	0.095400	1.54e-01
REACTOME FRS MEDIATED FGFR1 SIGNALING	23	3.66e-03	0.350000	1.54e-01
REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	59	3.97e-03	0.217000	1.63e-01
REACTOME SIGNALING BY FGFR4	40	4.16e-03	0.262000	1.67e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1	31	5.00e-03	0.291000	1.93e-01
REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM	23	5.05e-03	0.338000	1.93e-01
REACTOME SIGNALING BY NTRKS	132	5.35e-03	0.140000	2.00e-01
REACTOME SHC MEDIATED CASCADE FGFR1	21	6.23e-03	0.345000	2.27e-01
REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING	25	6.88e-03	0.312000	2.46e-01
REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS	8	7.05e-03	0.550000	2.46e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2	17	7.59e-03	0.374000	2.60e-01
REACTOME NEGATIVE REGULATION OF MAPK PATHWAY	41	7.79e-03	0.240000	2.61e-01
REACTOME FGFR1C LIGAND BINDING AND ACTIVATION	11	8.20e-03	0.460000	2.69e-01
REACTOME SIGNALING BY FGFR2 IN DISEASE	42	8.65e-03	0.234000	2.78e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR4	14	8.83e-03	0.404000	2.79e-01
REACTOME SIGNALING BY FGFR3	39	9.95e-03	0.238000	3.08e-01
REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	36	1.20e-02	0.242000	3.66e-01
REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE	63	1.30e-02	0.181000	3.85e-01
REACTOME FORMATION OF AXIAL MESODERM	14	1.32e-02	0.383000	3.85e-01
REACTOME HDACS DEACETYLATE HISTONES	85	1.34e-02	0.155000	3.85e-01
REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	12	1.42e-02	0.409000	4.02e-01
REACTOME POTENTIAL THERAPEUTICS FOR SARS	92	1.46e-02	0.147000	4.04e-01
REACTOME CELL CYCLE MITOTIC	539	1.49e-02	0.061300	4.04e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS	5	1.50e-02	0.628000	4.04e-01
REACTOME GASTRULATION	49	1.58e-02	0.199000	4.18e-01
REACTOME RHO GTPASES ACTIVATE FORMINS	136	1.62e-02	0.119000	4.22e-01
REACTOME METABOLISM OF NUCLEOTIDES	94	1.67e-02	0.143000	4.22e-01
REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION	100	1.68e-02	0.138000	4.22e-01
REACTOME CELL CYCLE	666	1.69e-02	0.054200	4.22e-01
REACTOME RAF ACTIVATION	33	1.81e-02	0.238000	4.43e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR2	29	1.86e-02	0.253000	4.49e-01
REACTOME RNA POLYMERASE I PROMOTER ESCAPE	83	1.90e-02	0.149000	4.50e-01
REACTOME MITOTIC METAPHASE AND ANAPHASE	228	1.92e-02	0.090000	4.50e-01
REACTOME TERMINAL PATHWAY OF COMPLEMENT	8	1.95e-02	-0.477000	4.51e-01
REACTOME FRS MEDIATED FGFR2 SIGNALING	24	1.99e-02	0.275000	4.51e-01
REACTOME PI 3K CASCADE FGFR2	22	2.01e-02	0.286000	4.51e-01
REACTOME NFE2L2 REGULATING ANTI OXIDANT DETOXIFICATION ENZYMES	17	2.07e-02	-0.324000	4.51e-01
REACTOME MISCELLANEOUS SUBSTRATES	12	2.07e-02	-0.386000	4.51e-01
REACTOME SIGNALING BY TGFB FAMILY MEMBERS	119	2.10e-02	0.123000	4.51e-01
REACTOME BILE ACID AND BILE SALT METABOLISM	45	2.12e-02	-0.199000	4.51e-01
REACTOME SARS COV 1 HOST INTERACTIONS	92	2.16e-02	0.139000	4.55e-01
REACTOME ONCOGENE INDUCED SENESCENCE	35	2.23e-02	0.223000	4.63e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	24	2.29e-02	-0.268000	4.70e-01
REACTOME NGF STIMULATED TRANSCRIPTION	38	2.35e-02	0.212000	4.76e-01
REACTOME PROTEIN LOCALIZATION	153	2.44e-02	0.105000	4.86e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR4	26	2.45e-02	0.255000	4.86e-01
REACTOME MTORC1 MEDIATED SIGNALLING	23	2.54e-02	0.269000	4.94e-01
REACTOME NERVOUS SYSTEM DEVELOPMENT	552	2.60e-02	0.055400	4.94e-01
REACTOME FRS MEDIATED FGFR4 SIGNALING	21	2.61e-02	0.280000	4.94e-01
REACTOME PI 3K CASCADE FGFR4	19	2.62e-02	0.295000	4.94e-01
REACTOME RHOB GTPASE CYCLE	67	2.66e-02	-0.157000	4.97e-01
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	263	2.78e-02	0.078800	5.03e-01
REACTOME SEPARATION OF SISTER CHROMATIDS	184	2.80e-02	0.093900	5.03e-01
REACTOME PI3K AKT SIGNALING IN CANCER	103	2.82e-02	0.125000	5.03e-01
REACTOME ANTIMICROBIAL PEPTIDES	76	2.82e-02	0.146000	5.03e-01
REACTOME HORMONE LIGAND BINDING RECEPTORS	12	3.02e-02	-0.361000	5.28e-01
REACTOME CELL CYCLE CHECKPOINTS	284	3.12e-02	0.074300	5.28e-01
REACTOME CHROMOSOME MAINTENANCE	130	3.14e-02	0.109000	5.28e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	27	3.15e-02	-0.239000	5.28e-01
REACTOME MELANIN BIOSYNTHESIS	5	3.18e-02	-0.554000	5.28e-01
REACTOME FATTY ACYL COA BIOSYNTHESIS	36	3.21e-02	0.206000	5.28e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL	15	3.23e-02	-0.319000	5.28e-01
REACTOME MITOTIC SPINDLE CHECKPOINT	109	3.25e-02	0.119000	5.28e-01
REACTOME FGFRL1 MODULATION OF FGFR1 SIGNALING	13	3.25e-02	0.343000	5.28e-01
REACTOME M PHASE	398	3.40e-02	0.061900	5.47e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR3	24	3.46e-02	0.249000	5.49e-01
REACTOME MICRORNA MIRNA BIOGENESIS	25	3.54e-02	0.243000	5.49e-01
REACTOME UCH PROTEINASES	99	3.54e-02	0.122000	5.49e-01
REACTOME GLUCONEOGENESIS	33	3.60e-02	0.211000	5.49e-01
REACTOME RESOLUTION OF SISTER CHROMATID COHESION	120	3.61e-02	0.111000	5.49e-01
REACTOME GLUCOSE METABOLISM	90	3.62e-02	0.128000	5.49e-01
REACTOME FRS MEDIATED FGFR3 SIGNALING	19	3.71e-02	0.276000	5.49e-01
REACTOME PI 3K CASCADE FGFR3	17	3.74e-02	0.292000	5.49e-01
REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	111	3.74e-02	0.114000	5.49e-01
REACTOME TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS	36	3.74e-02	0.200000	5.49e-01
REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	23	3.80e-02	0.250000	5.50e-01
REACTOME VLDL CLEARANCE	6	3.84e-02	0.488000	5.50e-01
REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R	52	3.85e-02	0.166000	5.50e-01
REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	49	3.91e-02	0.170000	5.53e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	34	3.96e-02	-0.204000	5.55e-01
REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS	418	4.15e-02	0.058100	5.77e-01
REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY	46	4.18e-02	0.173000	5.77e-01
REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT	222	4.29e-02	0.078900	5.86e-01
REACTOME BASE EXCISION REPAIR AP SITE FORMATION	59	4.35e-02	0.152000	5.86e-01
REACTOME SHC MEDIATED CASCADE FGFR4	19	4.36e-02	0.267000	5.86e-01
REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION	84	4.47e-02	0.127000	5.96e-01
REACTOME REGULATION OF INSULIN SECRETION	77	4.62e-02	-0.131000	6.04e-01
REACTOME REGULATION OF IFNG SIGNALING	14	4.66e-02	0.307000	6.04e-01
REACTOME TELOMERE MAINTENANCE	106	4.76e-02	0.111000	6.04e-01
REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS	113	4.77e-02	0.108000	6.04e-01
REACTOME PHASE II CONJUGATION OF COMPOUNDS	102	4.80e-02	-0.113000	6.04e-01
REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION	62	4.81e-02	0.145000	6.04e-01
REACTOME PP2A MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS	6	4.81e-02	0.466000	6.04e-01
REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS	299	4.88e-02	0.066200	6.04e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX	91	4.93e-02	0.119000	6.04e-01
REACTOME FGFR3B LIGAND BINDING AND ACTIVATION	7	4.95e-02	0.429000	6.04e-01
REACTOME UB SPECIFIC PROCESSING PROTEASES	187	5.08e-02	0.082800	6.04e-01
REACTOME ASPARAGINE N LINKED GLYCOSYLATION	299	5.13e-02	0.065500	6.04e-01
REACTOME SPRY REGULATION OF FGF SIGNALING	16	5.15e-02	0.281000	6.04e-01
REACTOME PARACETAMOL ADME	26	5.15e-02	-0.221000	6.04e-01
REACTOME SIGNALING BY WNT	318	5.17e-02	0.063500	6.04e-01
REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL	58	5.18e-02	0.148000	6.04e-01
REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS	43	5.23e-02	-0.171000	6.04e-01
REACTOME CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY	25	5.25e-02	-0.224000	6.04e-01
REACTOME FGFR3 LIGAND BINDING AND ACTIVATION	12	5.26e-02	0.323000	6.04e-01
REACTOME AMYLOID FIBER FORMATION	102	5.26e-02	0.111000	6.04e-01
REACTOME FREE FATTY ACIDS REGULATE INSULIN SECRETION	10	5.35e-02	-0.353000	6.10e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS	121	5.38e-02	0.101000	6.10e-01
REACTOME RHOQ GTPASE CYCLE	57	5.48e-02	-0.147000	6.16e-01
REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	17	5.51e-02	0.269000	6.16e-01
REACTOME DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE	76	5.72e-02	0.126000	6.32e-01
REACTOME METALLOTHIONEINS BIND METALS	11	5.76e-02	0.331000	6.32e-01
REACTOME MYOGENESIS	29	5.77e-02	-0.204000	6.32e-01
REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	93	5.85e-02	0.113000	6.32e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES	33	5.85e-02	-0.190000	6.32e-01
REACTOME HATS ACETYLATE HISTONES	129	5.89e-02	0.096300	6.32e-01
REACTOME ERK MAPK TARGETS	20	6.01e-02	0.243000	6.32e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES	16	6.08e-02	0.271000	6.32e-01
REACTOME RHOC GTPASE CYCLE	71	6.19e-02	-0.128000	6.32e-01
REACTOME INSULIN RECEPTOR SIGNALLING CASCADE	53	6.22e-02	0.148000	6.32e-01
REACTOME SHC MEDIATED CASCADE FGFR3	17	6.23e-02	0.261000	6.32e-01
REACTOME ABACAVIR TRANSMEMBRANE TRANSPORT	5	6.27e-02	-0.481000	6.32e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH CDK5	6	6.30e-02	0.438000	6.32e-01
REACTOME BIOLOGICAL OXIDATIONS	210	6.31e-02	-0.074400	6.32e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE GIP	12	6.31e-02	0.310000	6.32e-01
REACTOME DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX	83	6.35e-02	0.118000	6.32e-01
REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER	77	6.37e-02	0.122000	6.32e-01
REACTOME EPITHELIAL MESENCHYMAL TRANSITION EMT DURING GASTRULATION	7	6.48e-02	0.403000	6.32e-01
REACTOME LINOLEIC ACID LA METABOLISM	7	6.50e-02	0.403000	6.32e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	14	6.51e-02	0.285000	6.32e-01
REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	28	6.52e-02	-0.201000	6.32e-01
REACTOME ER TO GOLGI ANTEROGRADE TRANSPORT	152	6.59e-02	0.086400	6.32e-01
REACTOME FGFR2B LIGAND BINDING AND ACTIVATION	10	6.60e-02	0.336000	6.32e-01
REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	51	6.61e-02	0.149000	6.32e-01
REACTOME RHOJ GTPASE CYCLE	51	6.68e-02	-0.148000	6.32e-01
REACTOME RA BIOSYNTHESIS PATHWAY	22	6.73e-02	0.225000	6.32e-01
REACTOME SIGNALING BY INTERLEUKINS	444	6.74e-02	0.050600	6.32e-01
REACTOME TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS	26	6.74e-02	0.207000	6.32e-01
REACTOME SIGNALING BY FGFR IN DISEASE	62	6.77e-02	0.134000	6.32e-01
REACTOME SIGNALING BY ACTIVIN	15	6.84e-02	0.272000	6.32e-01
REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	22	6.85e-02	0.224000	6.32e-01
REACTOME IRS MEDIATED SIGNALLING	47	6.98e-02	0.153000	6.37e-01
REACTOME INFECTIOUS DISEASE	910	6.99e-02	0.035400	6.37e-01
REACTOME MAPK6 MAPK4 SIGNALING	91	7.02e-02	0.110000	6.37e-01
REACTOME SIGNALING BY NTRK2 TRKB	25	7.13e-02	0.208000	6.42e-01
REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL	41	7.18e-02	0.162000	6.42e-01
REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	20	7.19e-02	-0.232000	6.42e-01
REACTOME SARS COV 2 MODULATES AUTOPHAGY	11	7.30e-02	-0.312000	6.48e-01
REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN	37	7.39e-02	-0.170000	6.51e-01
REACTOME SIGNALING BY RECEPTOR TYROSINE KINASES	507	7.44e-02	0.046300	6.51e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA	27	7.45e-02	-0.198000	6.51e-01
REACTOME CTLA4 INHIBITORY SIGNALING	21	7.54e-02	0.224000	6.55e-01
REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION	145	7.61e-02	0.085300	6.55e-01
REACTOME SIGNALING BY NUCLEAR RECEPTORS	283	7.64e-02	0.061200	6.55e-01
REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	63	7.66e-02	-0.129000	6.55e-01
REACTOME SARS COV 1 INFECTION	136	7.74e-02	0.087700	6.57e-01
REACTOME MRNA SPLICING	197	7.77e-02	0.072900	6.57e-01
REACTOME SELECTIVE AUTOPHAGY	79	7.81e-02	0.115000	6.57e-01
REACTOME MITOCHONDRIAL TRANSLATION	93	7.90e-02	0.105000	6.62e-01
REACTOME RAB GERANYLGERANYLATION	57	8.00e-02	0.134000	6.64e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION	102	8.00e-02	0.100000	6.64e-01
REACTOME VISUAL PHOTOTRANSDUCTION	93	8.18e-02	0.104000	6.72e-01
REACTOME BASE EXCISION REPAIR	87	8.22e-02	0.108000	6.72e-01
REACTOME NONHOMOLOGOUS END JOINING NHEJ	64	8.27e-02	0.125000	6.72e-01
REACTOME CD209 DC SIGN SIGNALING	20	8.30e-02	-0.224000	6.72e-01
REACTOME TELOMERE C STRAND SYNTHESIS INITIATION	12	8.36e-02	0.288000	6.72e-01
REACTOME RHOG GTPASE CYCLE	71	8.42e-02	-0.119000	6.72e-01
REACTOME METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION	15	8.50e-02	0.257000	6.72e-01
REACTOME RECYCLING OF BILE ACIDS AND SALTS	18	8.50e-02	-0.234000	6.72e-01
REACTOME SIGNALING BY MRAS COMPLEX MUTANTS	7	8.56e-02	0.375000	6.72e-01
REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION	98	8.57e-02	0.100000	6.72e-01
REACTOME CELLULAR RESPONSE TO HYPOXIA	74	8.61e-02	0.115000	6.72e-01
REACTOME ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS	5	8.64e-02	0.443000	6.72e-01
REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE	52	8.64e-02	0.137000	6.72e-01
REACTOME TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT	18	8.72e-02	0.233000	6.75e-01
REACTOME SIGNALING BY FGFR2 IIIA TM	19	8.85e-02	0.226000	6.81e-01
REACTOME SYNTHESIS OF 5 EICOSATETRAENOIC ACIDS	9	8.88e-02	0.328000	6.81e-01
REACTOME CD163 MEDIATING AN ANTI INFLAMMATORY RESPONSE	9	8.92e-02	-0.327000	6.81e-01
REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	10	9.11e-02	-0.309000	6.90e-01
REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	66	9.20e-02	0.120000	6.90e-01
REACTOME CYTOSOLIC TRNA AMINOACYLATION	22	9.20e-02	0.208000	6.90e-01
REACTOME METHIONINE SALVAGE PATHWAY	6	9.21e-02	-0.397000	6.90e-01
REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21	59	9.26e-02	0.127000	6.91e-01
REACTOME GLUTAMATE AND GLUTAMINE METABOLISM	13	9.30e-02	0.269000	6.91e-01
REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	19	9.41e-02	0.222000	6.94e-01
REACTOME METALLOPROTEASE DUBS	36	9.43e-02	0.161000	6.94e-01
REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA	28	9.47e-02	0.182000	6.94e-01
REACTOME GLYCOLYSIS	70	9.56e-02	0.115000	6.98e-01
REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	21	9.67e-02	0.209000	7.03e-01
REACTOME MUSCLE CONTRACTION	197	9.80e-02	0.068400	7.09e-01
REACTOME POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE	25	9.90e-02	0.191000	7.13e-01
REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS	100	9.99e-02	0.095200	7.17e-01
REACTOME AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA	54	1.01e-01	0.129000	7.19e-01
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	55	1.03e-01	0.127000	7.26e-01
REACTOME SIGNALING BY PTK6	54	1.04e-01	0.128000	7.26e-01
REACTOME CONDENSATION OF PROPHASE CHROMOSOMES	66	1.04e-01	0.116000	7.26e-01
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION	138	1.04e-01	0.080200	7.26e-01
REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	183	1.04e-01	0.069600	7.26e-01
REACTOME PHYSIOLOGICAL FACTORS	14	1.05e-01	0.250000	7.26e-01
REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS	63	1.05e-01	0.118000	7.26e-01
REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	22	1.06e-01	0.199000	7.26e-01
REACTOME DNA REPAIR	321	1.06e-01	0.052500	7.26e-01
REACTOME REGULATION BY C FLIP	11	1.06e-01	-0.281000	7.27e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN	21	1.07e-01	0.203000	7.27e-01
REACTOME CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY	84	1.07e-01	0.102000	7.27e-01
REACTOME HDL REMODELING	10	1.08e-01	0.294000	7.29e-01
REACTOME CD28 DEPENDENT VAV1 PATHWAY	11	1.09e-01	0.279000	7.31e-01
REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	16	1.10e-01	0.231000	7.34e-01
REACTOME METABOLISM OF AMINE DERIVED HORMONES	17	1.12e-01	0.222000	7.47e-01
REACTOME BETA CATENIN PHOSPHORYLATION CASCADE	16	1.12e-01	0.229000	7.47e-01
REACTOME TRANSCRIPTIONAL REGULATION BY E2F6	32	1.13e-01	-0.162000	7.47e-01
REACTOME TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION	5	1.14e-01	0.408000	7.51e-01
REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	76	1.16e-01	0.104000	7.60e-01
REACTOME TRNA PROCESSING	105	1.18e-01	0.088300	7.60e-01
REACTOME INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	28	1.18e-01	0.171000	7.60e-01
REACTOME THE PHOTOTRANSDUCTION CASCADE	32	1.18e-01	0.160000	7.60e-01
REACTOME RAC1 GTPASE CYCLE	172	1.18e-01	-0.069000	7.60e-01
REACTOME DEUBIQUITINATION	260	1.19e-01	0.056100	7.60e-01
REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	16	1.19e-01	0.225000	7.60e-01
REACTOME COPI MEDIATED ANTEROGRADE TRANSPORT	101	1.20e-01	0.089600	7.60e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX2	117	1.20e-01	0.083300	7.60e-01
REACTOME ENOS ACTIVATION	11	1.20e-01	0.271000	7.60e-01
REACTOME ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM	12	1.21e-01	0.259000	7.61e-01
REACTOME FATTY ACIDS BOUND TO GPR40 FFAR1 REGULATE INSULIN SECRETION	8	1.21e-01	-0.316000	7.64e-01
REACTOME FOLDING OF ACTIN BY CCT TRIC	10	1.22e-01	0.283000	7.64e-01
REACTOME SYNTHESIS OF PA	38	1.24e-01	-0.144000	7.71e-01
REACTOME CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND	9	1.24e-01	-0.296000	7.71e-01
REACTOME PLATELET SENSITIZATION BY LDL	17	1.24e-01	0.215000	7.71e-01
REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	15	1.25e-01	0.229000	7.72e-01
REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	30	1.26e-01	-0.162000	7.73e-01
REACTOME REGULATION OF GENE EXPRESSION IN ENDOCRINE COMMITTED NEUROG3 PROGENITOR CELLS	5	1.27e-01	0.394000	7.80e-01
REACTOME REGULATION OF RAS BY GAPS	66	1.28e-01	0.108000	7.80e-01
REACTOME SIGNALING BY RETINOIC ACID	41	1.29e-01	0.137000	7.80e-01
REACTOME SYNTHESIS OF UDP N ACETYL GLUCOSAMINE	7	1.30e-01	0.331000	7.80e-01
REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	78	1.30e-01	0.099100	7.80e-01
REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION	10	1.31e-01	0.276000	7.80e-01
REACTOME CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT	19	1.31e-01	0.200000	7.80e-01
REACTOME NEGATIVE REGULATION OF ACTIVITY OF TFAP2 AP 2 FAMILY TRANSCRIPTION FACTORS	10	1.31e-01	0.276000	7.80e-01
REACTOME CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE	49	1.31e-01	0.125000	7.80e-01
REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION	60	1.32e-01	0.113000	7.80e-01
REACTOME HCMV LATE EVENTS	110	1.34e-01	0.082700	7.90e-01
REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	29	1.34e-01	0.161000	7.90e-01
REACTOME DEGRADATION OF CYSTEINE AND HOMOCYSTEINE	15	1.36e-01	0.223000	7.95e-01
REACTOME MEIOTIC SYNAPSIS	73	1.36e-01	0.101000	7.97e-01
REACTOME SYNTHESIS OF 12 EICOSATETRAENOIC ACID DERIVATIVES	7	1.38e-01	0.324000	8.00e-01
REACTOME IRE1ALPHA ACTIVATES CHAPERONES	48	1.38e-01	0.124000	8.00e-01
REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	15	1.39e-01	0.221000	8.05e-01
REACTOME ENDOGENOUS STEROLS	26	1.40e-01	-0.167000	8.05e-01
REACTOME SEMA4D IN SEMAPHORIN SIGNALING	24	1.40e-01	-0.174000	8.05e-01
REACTOME MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS	7	1.41e-01	0.321000	8.06e-01
REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	30	1.42e-01	-0.155000	8.08e-01
REACTOME ANDROGEN BIOSYNTHESIS	11	1.44e-01	0.254000	8.14e-01
REACTOME DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE	30	1.44e-01	0.154000	8.14e-01
REACTOME PTK6 REGULATES CELL CYCLE	6	1.45e-01	0.344000	8.14e-01
REACTOME MRNA SPLICING MINOR PATHWAY	49	1.45e-01	0.120000	8.14e-01
REACTOME BINDING OF TCF LEF CTNNB1 TO TARGET GENE PROMOTERS	8	1.45e-01	0.297000	8.14e-01
REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	19	1.49e-01	0.191000	8.28e-01
REACTOME FGFR2 ALTERNATIVE SPLICING	27	1.49e-01	0.161000	8.28e-01
REACTOME RUNX3 REGULATES NOTCH SIGNALING	13	1.50e-01	-0.231000	8.28e-01
REACTOME HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE	43	1.50e-01	-0.127000	8.28e-01
REACTOME RHO GTPASE EFFECTORS	305	1.50e-01	0.047900	8.28e-01
REACTOME LYSINE CATABOLISM	12	1.51e-01	0.239000	8.30e-01
REACTOME RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION	6	1.52e-01	0.338000	8.30e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS	14	1.52e-01	0.221000	8.30e-01
REACTOME CYCLIN D ASSOCIATED EVENTS IN G1	46	1.55e-01	0.121000	8.42e-01
REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP	104	1.55e-01	0.080600	8.42e-01
REACTOME NUCLEOTIDE CATABOLISM	35	1.56e-01	0.138000	8.44e-01
REACTOME RHOD GTPASE CYCLE	49	1.57e-01	-0.117000	8.46e-01
REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT	159	1.58e-01	0.064900	8.46e-01
REACTOME PEPTIDE LIGAND BINDING RECEPTORS	188	1.58e-01	0.059700	8.46e-01
REACTOME GERM LAYER FORMATION AT GASTRULATION	17	1.59e-01	0.197000	8.46e-01
REACTOME DISEASES OF DNA REPAIR	51	1.60e-01	-0.114000	8.46e-01
REACTOME MITOCHONDRIAL PROTEIN IMPORT	58	1.60e-01	0.107000	8.46e-01
REACTOME ACTIVATION OF NIMA KINASES NEK9 NEK6 NEK7	7	1.61e-01	-0.306000	8.46e-01
REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION	74	1.61e-01	-0.094300	8.46e-01
REACTOME HEME DEGRADATION	15	1.61e-01	-0.209000	8.47e-01
REACTOME RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES TREGS	9	1.63e-01	0.269000	8.48e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG	7	1.63e-01	0.305000	8.48e-01
REACTOME NUCLEOTIDE EXCISION REPAIR	107	1.64e-01	0.077800	8.54e-01
REACTOME DISINHIBITION OF SNARE FORMATION	5	1.67e-01	0.357000	8.59e-01
REACTOME ADHERENS JUNCTIONS INTERACTIONS	33	1.67e-01	-0.139000	8.59e-01
REACTOME HSF1 DEPENDENT TRANSACTIVATION	37	1.67e-01	0.131000	8.59e-01
REACTOME PROCESSING OF INTRONLESS PRE MRNAS	19	1.67e-01	0.183000	8.59e-01
REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	11	1.68e-01	0.240000	8.61e-01
REACTOME RHO GTPASES ACTIVATE ROCKS	19	1.69e-01	-0.182000	8.61e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	11	1.70e-01	0.239000	8.64e-01
REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	86	1.71e-01	0.085500	8.64e-01
REACTOME LYSOSOME VESICLE BIOGENESIS	33	1.71e-01	-0.138000	8.64e-01
REACTOME ACTIVATION OF TRKA RECEPTORS	6	1.72e-01	0.322000	8.64e-01
REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY	5	1.72e-01	-0.352000	8.64e-01
REACTOME RUNX3 REGULATES WNT SIGNALING	8	1.73e-01	0.278000	8.64e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX3	94	1.74e-01	0.081200	8.64e-01
REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	26	1.74e-01	0.154000	8.64e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS	15	1.74e-01	0.203000	8.64e-01
REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	15	1.75e-01	-0.202000	8.64e-01
REACTOME RETINOID CYCLE DISEASE EVENTS	11	1.76e-01	0.236000	8.66e-01
REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC	198	1.76e-01	0.055700	8.66e-01
REACTOME PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING	11	1.77e-01	0.235000	8.66e-01
REACTOME S PHASE	159	1.78e-01	0.061900	8.66e-01
REACTOME METABOLISM OF STEROIDS	150	1.78e-01	-0.063700	8.66e-01
REACTOME IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN	5	1.79e-01	0.347000	8.66e-01
REACTOME GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION	42	1.79e-01	-0.120000	8.66e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES	61	1.80e-01	0.099300	8.66e-01
REACTOME DECTIN 2 FAMILY	26	1.80e-01	-0.152000	8.66e-01
REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	16	1.81e-01	-0.193000	8.69e-01
REACTOME SUMOYLATION OF TRANSCRIPTION FACTORS	20	1.82e-01	0.172000	8.69e-01
REACTOME G ALPHA S SIGNALLING EVENTS	155	1.83e-01	-0.062000	8.69e-01
REACTOME TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER	76	1.83e-01	0.088300	8.69e-01
REACTOME INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING	103	1.84e-01	0.075800	8.69e-01
REACTOME GLYCEROPHOSPHOLIPID CATABOLISM	7	1.84e-01	-0.290000	8.69e-01
REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	101	1.84e-01	-0.076400	8.70e-01
REACTOME GLYCOGEN STORAGE DISEASES	15	1.87e-01	-0.197000	8.77e-01
REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES	14	1.91e-01	0.202000	8.77e-01
REACTOME FOXO MEDIATED TRANSCRIPTION	65	1.91e-01	0.093900	8.77e-01
REACTOME RHOH GTPASE CYCLE	37	1.91e-01	-0.124000	8.77e-01
REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY	72	1.91e-01	0.089100	8.77e-01
REACTOME TRANSPORT OF RCBL WITHIN THE BODY	8	1.92e-01	-0.267000	8.77e-01
REACTOME PURINE SALVAGE	12	1.92e-01	0.218000	8.77e-01
REACTOME GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION	14	1.92e-01	0.201000	8.77e-01
REACTOME HCMV EARLY EVENTS	128	1.93e-01	0.066700	8.77e-01
REACTOME OAS ANTIVIRAL RESPONSE	8	1.93e-01	0.266000	8.77e-01
REACTOME ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA	5	1.93e-01	-0.336000	8.77e-01
REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX	85	1.93e-01	0.081600	8.77e-01
REACTOME COPII MEDIATED VESICLE TRANSPORT	66	1.94e-01	0.092400	8.77e-01
REACTOME BETA DEFENSINS	27	1.94e-01	0.144000	8.77e-01
REACTOME ACYL CHAIN REMODELING OF CL	5	1.94e-01	-0.335000	8.77e-01
REACTOME MITOTIC PROPHASE	134	1.97e-01	0.064600	8.77e-01
REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	62	1.98e-01	0.094600	8.77e-01
REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES	29	1.98e-01	0.138000	8.77e-01
REACTOME HIV INFECTION	223	1.98e-01	0.050000	8.77e-01
REACTOME DNA DOUBLE STRAND BREAK RESPONSE	74	1.99e-01	0.086300	8.77e-01
REACTOME BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA	5	2.00e-01	0.331000	8.77e-01
REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	15	2.01e-01	-0.191000	8.77e-01
REACTOME METABOLISM OF LIPIDS	709	2.01e-01	-0.028200	8.77e-01
REACTOME PHASE 4 RESTING MEMBRANE POTENTIAL	19	2.02e-01	0.169000	8.77e-01
REACTOME CREB3 FACTORS ACTIVATE GENES	8	2.02e-01	0.260000	8.77e-01
REACTOME PTEN REGULATION	135	2.03e-01	0.063500	8.77e-01
REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	22	2.03e-01	-0.157000	8.77e-01
REACTOME NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY	6	2.03e-01	0.300000	8.77e-01
REACTOME CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND	16	2.04e-01	-0.183000	8.77e-01
REACTOME SEMAPHORIN INTERACTIONS	61	2.05e-01	-0.093700	8.77e-01
REACTOME DEFENSINS	33	2.06e-01	0.127000	8.77e-01
REACTOME NEGATIVE REGULATION OF NOTCH4 SIGNALING	53	2.06e-01	0.100000	8.77e-01
REACTOME ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION	16	2.07e-01	-0.182000	8.77e-01
REACTOME REGULATION OF BETA CELL DEVELOPMENT	41	2.07e-01	0.114000	8.77e-01
REACTOME CELLULAR RESPONSE TO HEAT STRESS	99	2.08e-01	0.073300	8.77e-01
REACTOME PROTEIN FOLDING	96	2.08e-01	0.074300	8.77e-01
REACTOME NGF INDEPENDANT TRKA ACTIVATION	5	2.08e-01	0.325000	8.77e-01
REACTOME COMPLEMENT CASCADE	54	2.09e-01	-0.098800	8.77e-01
REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	17	2.09e-01	-0.176000	8.77e-01
REACTOME INTERLEUKIN 20 FAMILY SIGNALING	25	2.09e-01	0.145000	8.77e-01
REACTOME AGGREPHAGY	42	2.10e-01	0.112000	8.77e-01
REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	111	2.10e-01	0.068900	8.77e-01
REACTOME PHASE 1 INACTIVATION OF FAST NA CHANNELS	6	2.11e-01	-0.295000	8.77e-01
REACTOME METABOLISM OF POLYAMINES	56	2.12e-01	0.096400	8.77e-01
REACTOME GOLGI TO ER RETROGRADE TRANSPORT	132	2.12e-01	0.062900	8.77e-01
REACTOME HCMV INFECTION	152	2.12e-01	0.058600	8.77e-01
REACTOME NEF MEDIATED CD8 DOWN REGULATION	7	2.13e-01	-0.272000	8.77e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3	11	2.13e-01	0.217000	8.77e-01
REACTOME COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC	98	2.15e-01	0.072600	8.77e-01
REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX	21	2.15e-01	-0.156000	8.77e-01
REACTOME PREDNISONE ADME	10	2.16e-01	-0.226000	8.77e-01
REACTOME CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION	24	2.17e-01	0.146000	8.77e-01
REACTOME DISEASES OF CARBOHYDRATE METABOLISM	31	2.18e-01	-0.128000	8.77e-01
REACTOME TRNA AMINOACYLATION	40	2.18e-01	0.112000	8.77e-01
REACTOME DNA REPLICATION PRE INITIATION	150	2.19e-01	0.058200	8.77e-01
REACTOME TRANSPORT OF NUCLEOTIDE SUGARS	8	2.19e-01	-0.251000	8.77e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION TERMINATION	30	2.20e-01	0.130000	8.77e-01
REACTOME DNA METHYLATION	58	2.20e-01	0.093200	8.77e-01
REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES	77	2.20e-01	-0.080900	8.77e-01
REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS	29	2.20e-01	0.132000	8.77e-01
REACTOME MTOR SIGNALLING	40	2.20e-01	0.112000	8.77e-01
REACTOME DRUG ADME	103	2.21e-01	-0.069900	8.77e-01
REACTOME REPRESSION OF WNT TARGET GENES	14	2.21e-01	0.189000	8.77e-01
REACTOME O LINKED GLYCOSYLATION OF MUCINS	61	2.21e-01	-0.090600	8.77e-01
REACTOME RESPONSE TO METAL IONS	14	2.21e-01	0.189000	8.77e-01
REACTOME MEMBRANE TRAFFICKING	603	2.22e-01	0.029100	8.77e-01
REACTOME SARS COV INFECTIONS	392	2.22e-01	0.035900	8.77e-01
REACTOME SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS	16	2.22e-01	0.176000	8.77e-01
REACTOME TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS	82	2.24e-01	0.077600	8.81e-01
REACTOME GLYCOGEN SYNTHESIS	13	2.25e-01	-0.194000	8.81e-01
REACTOME RAC3 GTPASE CYCLE	85	2.26e-01	-0.076000	8.81e-01
REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION	62	2.26e-01	0.088900	8.81e-01
REACTOME GAP JUNCTION ASSEMBLY	36	2.26e-01	0.117000	8.81e-01
REACTOME RAC2 GTPASE CYCLE	81	2.27e-01	-0.077600	8.81e-01
REACTOME ASPIRIN ADME	42	2.28e-01	-0.107000	8.81e-01
REACTOME INTERLEUKIN 2 SIGNALING	11	2.30e-01	0.209000	8.81e-01
REACTOME DIGESTION OF DIETARY LIPID	7	2.30e-01	-0.262000	8.81e-01
REACTOME HEME SIGNALING	47	2.30e-01	-0.101000	8.81e-01
REACTOME G1 S DNA DAMAGE CHECKPOINTS	67	2.31e-01	0.084700	8.81e-01
REACTOME HDL CLEARANCE	5	2.31e-01	0.310000	8.81e-01
REACTOME COSTIMULATION BY THE CD28 FAMILY	64	2.32e-01	0.086400	8.81e-01
REACTOME ESTROGEN BIOSYNTHESIS	6	2.32e-01	0.282000	8.81e-01
REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	134	2.32e-01	-0.059800	8.81e-01
REACTOME RORA ACTIVATES GENE EXPRESSION	17	2.33e-01	-0.167000	8.81e-01
REACTOME ORGANIC ANION TRANSPORT	5	2.34e-01	0.308000	8.81e-01
REACTOME SUMOYLATION OF DNA METHYLATION PROTEINS	16	2.34e-01	-0.172000	8.81e-01
REACTOME PRE NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM	6	2.34e-01	-0.280000	8.81e-01
REACTOME DIGESTION AND ABSORPTION	22	2.36e-01	-0.146000	8.81e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES	43	2.36e-01	-0.104000	8.81e-01
REACTOME STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS	10	2.37e-01	0.216000	8.81e-01
REACTOME TYPE I HEMIDESMOSOME ASSEMBLY	11	2.37e-01	-0.206000	8.81e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2	13	2.37e-01	-0.189000	8.81e-01
REACTOME METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES	33	2.38e-01	-0.119000	8.81e-01
REACTOME MYOCLONIC EPILEPSY OF LAFORA	9	2.38e-01	-0.227000	8.81e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES	8	2.39e-01	0.241000	8.81e-01
REACTOME HIV LIFE CYCLE	145	2.39e-01	0.056700	8.81e-01
REACTOME REGULATION OF NPAS4 GENE EXPRESSION	13	2.40e-01	0.188000	8.81e-01
REACTOME CD22 MEDIATED BCR REGULATION	5	2.41e-01	-0.303000	8.81e-01
REACTOME NEUROTRANSMITTER CLEARANCE	9	2.41e-01	0.226000	8.81e-01
REACTOME PI METABOLISM	79	2.41e-01	-0.076300	8.81e-01
REACTOME RHO GTPASES ACTIVATE PAKS	19	2.42e-01	-0.155000	8.81e-01
REACTOME G PROTEIN MEDIATED EVENTS	53	2.42e-01	-0.093000	8.81e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS	9	2.42e-01	-0.225000	8.81e-01
REACTOME EICOSANOIDS	12	2.43e-01	-0.195000	8.82e-01
REACTOME ACTIVATION OF MATRIX METALLOPROTEINASES	30	2.44e-01	-0.123000	8.84e-01
REACTOME CATION COUPLED CHLORIDE COTRANSPORTERS	7	2.45e-01	-0.254000	8.84e-01
REACTOME FORMATION OF TC NER PRE INCISION COMPLEX	51	2.46e-01	0.094000	8.85e-01
REACTOME HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR IN THE PRESENCE OF LIGAND	55	2.47e-01	0.090300	8.85e-01
REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	38	2.47e-01	0.108000	8.85e-01
REACTOME DNA DAMAGE RECOGNITION IN GG NER	36	2.47e-01	0.111000	8.85e-01
REACTOME DNA REPLICATION	178	2.48e-01	0.050200	8.85e-01
REACTOME LRR FLII INTERACTING PROTEIN 1 LRRFIP1 ACTIVATES TYPE I IFN PRODUCTION	5	2.48e-01	-0.298000	8.85e-01
REACTOME NECTIN NECL TRANS HETERODIMERIZATION	7	2.49e-01	-0.252000	8.85e-01
REACTOME PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1	9	2.49e-01	0.222000	8.85e-01
REACTOME GAP JUNCTION TRAFFICKING AND REGULATION	49	2.50e-01	0.095000	8.86e-01
REACTOME CGMP EFFECTS	16	2.51e-01	-0.166000	8.88e-01
REACTOME ESR MEDIATED SIGNALING	210	2.53e-01	0.045800	8.90e-01
REACTOME INTEGRATION OF ENERGY METABOLISM	105	2.53e-01	-0.064600	8.90e-01
REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX	39	2.54e-01	0.105000	8.90e-01
REACTOME ESTROGEN DEPENDENT GENE EXPRESSION	140	2.55e-01	0.055800	8.90e-01
REACTOME NEUREXINS AND NEUROLIGINS	51	2.55e-01	-0.092200	8.90e-01
REACTOME MHC CLASS II ANTIGEN PRESENTATION	121	2.55e-01	-0.060000	8.90e-01
REACTOME SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS	43	2.56e-01	0.100000	8.91e-01
REACTOME HIV ELONGATION ARREST AND RECOVERY	33	2.57e-01	0.114000	8.91e-01
REACTOME THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT	77	2.57e-01	0.074800	8.91e-01
REACTOME INSULIN RECEPTOR RECYCLING	29	2.60e-01	-0.121000	8.97e-01
REACTOME RUNX3 REGULATES YAP1 MEDIATED TRANSCRIPTION	8	2.60e-01	0.230000	8.97e-01
REACTOME IRAK1 RECRUITS IKK COMPLEX	12	2.62e-01	0.187000	8.97e-01
REACTOME MIRO GTPASE CYCLE	8	2.62e-01	0.229000	8.97e-01
REACTOME CLEC7A INFLAMMASOME PATHWAY	6	2.62e-01	0.264000	8.97e-01
REACTOME DEGRADATION OF DVL	56	2.62e-01	0.086600	8.97e-01
REACTOME MITOCHONDRIAL UNCOUPLING	5	2.63e-01	-0.289000	8.97e-01
REACTOME INTERLEUKIN 23 SIGNALING	9	2.63e-01	-0.215000	8.97e-01
REACTOME VITAMIN C ASCORBATE METABOLISM	8	2.64e-01	-0.228000	8.97e-01
REACTOME ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT	23	2.65e-01	0.134000	8.97e-01
REACTOME SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER	15	2.65e-01	-0.166000	8.97e-01
REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3	679	2.66e-01	0.025100	8.97e-01
REACTOME PEROXISOMAL PROTEIN IMPORT	62	2.68e-01	0.081400	8.97e-01
REACTOME FCGR3A MEDIATED IL10 SYNTHESIS	36	2.68e-01	-0.107000	8.97e-01
REACTOME TNFR2 NON CANONICAL NF KB PATHWAY	96	2.68e-01	0.065400	8.97e-01
REACTOME LEISHMANIA INFECTION	156	2.69e-01	-0.051300	8.97e-01
REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	11	2.69e-01	0.192000	8.97e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH PI3K	7	2.70e-01	0.241000	8.97e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1	229	2.70e-01	0.042300	8.97e-01
REACTOME DEGRADATION OF GLI1 BY THE PROTEASOME	59	2.70e-01	0.083000	8.97e-01
REACTOME COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING	32	2.70e-01	0.113000	8.97e-01
REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	15	2.70e-01	0.164000	8.97e-01
REACTOME G ALPHA 12 13 SIGNALLING EVENTS	74	2.71e-01	-0.074000	8.97e-01
REACTOME VOLTAGE GATED POTASSIUM CHANNELS	42	2.72e-01	-0.098000	8.97e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING	6	2.73e-01	0.258000	8.97e-01
REACTOME FGFR1B LIGAND BINDING AND ACTIVATION	6	2.74e-01	0.258000	8.97e-01
REACTOME ETHANOL OXIDATION	12	2.74e-01	0.182000	8.97e-01
REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	67	2.75e-01	-0.077100	8.97e-01
REACTOME ACTIVATION OF RAC1	12	2.75e-01	-0.182000	8.97e-01
REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3	59	2.76e-01	0.082000	8.97e-01
REACTOME CS DS DEGRADATION	12	2.77e-01	-0.181000	8.97e-01
REACTOME AUTOPHAGY	144	2.78e-01	0.052400	8.97e-01
REACTOME DIGESTION	17	2.79e-01	-0.152000	8.97e-01
REACTOME CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER	25	2.80e-01	0.125000	8.97e-01
REACTOME REGULATION OF NPAS4 GENE TRANSCRIPTION	5	2.80e-01	0.279000	8.97e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE	74	2.80e-01	0.072600	8.97e-01
REACTOME ERYTHROPOIETIN ACTIVATES RAS	14	2.80e-01	0.167000	8.97e-01
REACTOME SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS	14	2.80e-01	0.167000	8.97e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE	5	2.81e-01	-0.279000	8.97e-01
REACTOME SUMOYLATION OF RNA BINDING PROTEINS	47	2.81e-01	-0.090800	8.97e-01
REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER	81	2.82e-01	0.069200	8.97e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION	45	2.82e-01	0.092800	8.97e-01
REACTOME REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM	11	2.82e-01	0.187000	8.97e-01
REACTOME PHOSPHOLIPID METABOLISM	201	2.84e-01	-0.043800	8.99e-01
REACTOME OPSINS	7	2.84e-01	-0.234000	8.99e-01
REACTOME RHOA GTPASE CYCLE	142	2.85e-01	-0.052000	8.99e-01
REACTOME NEUTROPHIL DEGRANULATION	460	2.85e-01	0.029100	8.99e-01
REACTOME RUNX3 REGULATES P14 ARF	10	2.86e-01	-0.195000	9.02e-01
REACTOME VASOPRESSIN LIKE RECEPTORS	5	2.88e-01	0.274000	9.07e-01
REACTOME LGI ADAM INTERACTIONS	14	2.90e-01	0.163000	9.10e-01
REACTOME BETA CATENIN INDEPENDENT WNT SIGNALING	145	2.92e-01	0.050700	9.11e-01
REACTOME PROTEIN METHYLATION	17	2.92e-01	0.148000	9.11e-01
REACTOME FATTY ACIDS	15	2.92e-01	-0.157000	9.11e-01
REACTOME OTHER SEMAPHORIN INTERACTIONS	18	2.94e-01	-0.143000	9.15e-01
REACTOME RNA POLYMERASE II TRANSCRIBES SNRNA GENES	77	2.94e-01	0.069100	9.15e-01
REACTOME RET SIGNALING	40	2.95e-01	0.095700	9.15e-01
REACTOME BETA OXIDATION OF PRISTANOYL COA	9	2.97e-01	-0.201000	9.18e-01
REACTOME MITOTIC PROMETAPHASE	194	2.97e-01	0.043400	9.18e-01
REACTOME PROTEIN REPAIR	6	2.98e-01	0.245000	9.18e-01
REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS	12	2.98e-01	0.173000	9.18e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1	16	2.98e-01	-0.150000	9.18e-01
REACTOME SARS COV 2 ACTIVATES MODULATES INNATE AND ADAPTIVE IMMUNE RESPONSES	118	3.00e-01	-0.055200	9.20e-01
REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	23	3.01e-01	0.125000	9.20e-01
REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION	90	3.01e-01	0.063100	9.20e-01
REACTOME SIGNALING BY MST1	5	3.02e-01	0.267000	9.21e-01
REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS	101	3.04e-01	-0.059200	9.25e-01
REACTOME PINK1 PRKN MEDIATED MITOPHAGY	22	3.04e-01	0.127000	9.25e-01
REACTOME AMINE LIGAND BINDING RECEPTORS	40	3.05e-01	-0.093700	9.25e-01
REACTOME NUCLEAR ENVELOPE NE REASSEMBLY	74	3.05e-01	0.068900	9.25e-01
REACTOME PURINE CATABOLISM	17	3.08e-01	0.143000	9.28e-01
REACTOME MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION	15	3.08e-01	-0.152000	9.28e-01
REACTOME ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS	17	3.09e-01	0.143000	9.30e-01
REACTOME PCP CE PATHWAY	91	3.09e-01	0.061600	9.30e-01
REACTOME DEFECTIVE RIPK1 MEDIATED REGULATED NECROSIS	7	3.11e-01	-0.221000	9.32e-01
REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	46	3.12e-01	0.086200	9.32e-01
REACTOME REGULATION OF LIPID METABOLISM BY PPARALPHA	115	3.14e-01	-0.054300	9.32e-01
REACTOME RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION	22	3.14e-01	0.124000	9.32e-01
REACTOME FREE FATTY ACID RECEPTORS	5	3.15e-01	-0.259000	9.32e-01
REACTOME METAL ION SLC TRANSPORTERS	23	3.16e-01	0.121000	9.32e-01
REACTOME TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA	17	3.17e-01	-0.140000	9.32e-01
REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	160	3.17e-01	-0.045900	9.32e-01
REACTOME HEME BIOSYNTHESIS	13	3.17e-01	0.160000	9.32e-01
REACTOME CD28 CO STIMULATION	32	3.18e-01	0.102000	9.32e-01
REACTOME RESPIRATORY ELECTRON TRANSPORT	90	3.18e-01	0.060900	9.32e-01
REACTOME REGULATION OF FZD BY UBIQUITINATION	21	3.18e-01	0.126000	9.32e-01
REACTOME L1CAM INTERACTIONS	112	3.19e-01	-0.054600	9.32e-01
REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS	60	3.19e-01	0.074300	9.32e-01
REACTOME SIGNALING BY INSULIN RECEPTOR	80	3.21e-01	0.064200	9.32e-01
REACTOME PROTEIN UBIQUITINATION	76	3.21e-01	0.065900	9.32e-01
REACTOME COLLAGEN FORMATION	88	3.22e-01	-0.061100	9.32e-01
REACTOME SIGNALING BY BMP	27	3.23e-01	0.110000	9.32e-01
REACTOME BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA	6	3.23e-01	0.233000	9.32e-01
REACTOME RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA	7	3.23e-01	0.216000	9.32e-01
REACTOME DUAL INCISION IN TC NER	63	3.24e-01	0.071800	9.32e-01
REACTOME SIGNALING BY WNT IN CANCER	32	3.24e-01	0.101000	9.32e-01
REACTOME MATURATION OF SARS COV 2 SPIKE PROTEIN	35	3.25e-01	-0.096100	9.32e-01
REACTOME SIGNALING BY NOTCH4	80	3.27e-01	0.063300	9.32e-01
REACTOME SYNTHESIS OF DOLICHYL PHOSPHATE	6	3.28e-01	0.231000	9.32e-01
REACTOME SIGNALING BY NOTCH1 T 7 9 NOTCH1 M1580 K2555 TRANSLOCATION MUTANT	7	3.29e-01	-0.213000	9.32e-01
REACTOME RELAXIN RECEPTORS	8	3.29e-01	-0.199000	9.32e-01
REACTOME NEGATIVE REGULATION OF FLT3	15	3.29e-01	-0.145000	9.32e-01
REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION	20	3.30e-01	0.126000	9.32e-01
REACTOME LIPOPHAGY	9	3.31e-01	0.187000	9.32e-01
REACTOME ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS	20	3.31e-01	0.126000	9.32e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS	14	3.31e-01	0.150000	9.32e-01
REACTOME ORGANIC CATION TRANSPORT	10	3.33e-01	0.177000	9.32e-01
REACTOME RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION	6	3.33e-01	-0.228000	9.32e-01
REACTOME POLB DEPENDENT LONG PATCH BASE EXCISION REPAIR	8	3.33e-01	-0.198000	9.32e-01
REACTOME REGULATION OF RUNX3 EXPRESSION AND ACTIVITY	54	3.33e-01	0.076100	9.32e-01
REACTOME LIGAND RECEPTOR INTERACTIONS	8	3.36e-01	0.196000	9.32e-01
REACTOME XENOBIOTICS	22	3.36e-01	-0.118000	9.32e-01
REACTOME OTHER INTERLEUKIN SIGNALING	24	3.37e-01	0.113000	9.32e-01
REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES	27	3.38e-01	0.107000	9.32e-01
REACTOME P75NTR SIGNALS VIA NF KB	15	3.39e-01	0.143000	9.32e-01
REACTOME ORGANIC ANION TRANSPORTERS	10	3.39e-01	-0.175000	9.32e-01
REACTOME CIPROFLOXACIN ADME	5	3.39e-01	-0.247000	9.32e-01
REACTOME REPRODUCTION	136	3.42e-01	0.047200	9.32e-01
REACTOME GLYCOGEN METABOLISM	22	3.43e-01	-0.117000	9.32e-01
REACTOME APOPTOTIC EXECUTION PHASE	49	3.44e-01	-0.078200	9.32e-01
REACTOME ABC TRANSPORTER DISORDERS	76	3.44e-01	0.062800	9.32e-01
REACTOME VESICLE MEDIATED TRANSPORT	642	3.45e-01	0.021900	9.32e-01
REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING	34	3.46e-01	0.093400	9.32e-01
REACTOME REGULATION OF KIT SIGNALING	16	3.46e-01	-0.136000	9.32e-01
REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION	68	3.47e-01	0.066000	9.32e-01
REACTOME MRNA CAPPING	28	3.47e-01	0.103000	9.32e-01
REACTOME KERATINIZATION	210	3.48e-01	-0.037500	9.32e-01
REACTOME SIGNALING BY NODAL	20	3.49e-01	0.121000	9.32e-01
REACTOME RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK	47	3.49e-01	0.079000	9.32e-01
REACTOME NEPHRIN FAMILY INTERACTIONS	22	3.49e-01	-0.115000	9.32e-01
REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS	18	3.50e-01	-0.127000	9.32e-01
REACTOME EGFR DOWNREGULATION	30	3.50e-01	-0.098600	9.32e-01
REACTOME REGULATION OF NPAS4 MRNA TRANSLATION	9	3.51e-01	0.180000	9.32e-01
REACTOME CHROMATIN MODIFYING ENZYMES	252	3.52e-01	0.034100	9.32e-01
REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	15	3.52e-01	0.139000	9.32e-01
REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	54	3.52e-01	0.073200	9.32e-01
REACTOME RNA POLYMERASE III CHAIN ELONGATION	18	3.52e-01	0.127000	9.32e-01
REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION	42	3.53e-01	-0.082900	9.32e-01
REACTOME TBC RABGAPS	40	3.53e-01	0.084800	9.32e-01
REACTOME COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING	38	3.54e-01	0.086900	9.32e-01
REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION	35	3.54e-01	0.090500	9.32e-01
REACTOME TRANSPORT AND SYNTHESIS OF PAPS	6	3.55e-01	-0.218000	9.32e-01
REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE	19	3.56e-01	0.122000	9.32e-01
REACTOME SIGNALING BY ERBB4	57	3.57e-01	-0.070600	9.32e-01
REACTOME FBXW7 MUTANTS AND NOTCH1 IN CANCER	5	3.58e-01	-0.237000	9.32e-01
REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX	15	3.59e-01	0.137000	9.32e-01
REACTOME REGULATION OF PTEN STABILITY AND ACTIVITY	67	3.60e-01	0.064700	9.32e-01
REACTOME GAB1 SIGNALOSOME	17	3.60e-01	-0.128000	9.32e-01
REACTOME TRYPTOPHAN CATABOLISM	14	3.61e-01	0.141000	9.32e-01
REACTOME TELOMERE EXTENSION BY TELOMERASE	22	3.61e-01	0.112000	9.32e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH RAS	9	3.63e-01	0.175000	9.32e-01
REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	29	3.64e-01	0.097400	9.32e-01
REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	23	3.64e-01	-0.109000	9.32e-01
REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III	31	3.64e-01	0.094100	9.32e-01
REACTOME SARS COV 2 TARGETS PDZ PROTEINS IN CELL CELL JUNCTION	5	3.65e-01	0.234000	9.32e-01
REACTOME HDR THROUGH HOMOLOGOUS RECOMBINATION HRR	66	3.65e-01	-0.064500	9.32e-01
REACTOME GAP JUNCTION DEGRADATION	12	3.65e-01	0.151000	9.32e-01
REACTOME NEF AND SIGNAL TRANSDUCTION	8	3.65e-01	0.185000	9.32e-01
REACTOME INLA MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS	9	3.66e-01	0.174000	9.32e-01
REACTOME ARACHIDONATE PRODUCTION FROM DAG	5	3.66e-01	0.233000	9.32e-01
REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	11	3.66e-01	-0.157000	9.32e-01
REACTOME GENE SILENCING BY RNA	133	3.67e-01	0.045300	9.32e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE	11	3.67e-01	-0.157000	9.32e-01
REACTOME SIGNALING BY EGFR	49	3.68e-01	-0.074400	9.32e-01
REACTOME ACYL CHAIN REMODELLING OF PE	29	3.68e-01	0.096600	9.32e-01
REACTOME FASL CD95L SIGNALING	5	3.68e-01	-0.232000	9.32e-01
REACTOME SIGNAL TRANSDUCTION BY L1	20	3.69e-01	0.116000	9.32e-01
REACTOME CDC42 GTPASE CYCLE	144	3.70e-01	-0.043300	9.32e-01
REACTOME ERYTHROPOIETIN ACTIVATES STAT5	7	3.70e-01	0.196000	9.32e-01
REACTOME LIPID PARTICLE ORGANIZATION	6	3.70e-01	0.211000	9.32e-01
REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING	12	3.71e-01	-0.149000	9.32e-01
REACTOME RIPK1 MEDIATED REGULATED NECROSIS	30	3.71e-01	-0.094400	9.32e-01
REACTOME COMMON PATHWAY OF FIBRIN CLOT FORMATION	21	3.71e-01	0.113000	9.32e-01
REACTOME TRANSCRIPTION OF THE HIV GENOME	66	3.72e-01	0.063500	9.32e-01
REACTOME HIV TRANSCRIPTION ELONGATION	42	3.72e-01	0.079600	9.32e-01
REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX	32	3.72e-01	0.091100	9.32e-01
REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION	31	3.73e-01	0.092500	9.32e-01
REACTOME GLUTATHIONE CONJUGATION	33	3.74e-01	-0.089400	9.32e-01
REACTOME GDP FUCOSE BIOSYNTHESIS	6	3.74e-01	-0.209000	9.32e-01
REACTOME SIGNALING BY NOTCH3	48	3.75e-01	-0.074000	9.32e-01
REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	30	3.75e-01	-0.093500	9.32e-01
REACTOME RND1 GTPASE CYCLE	41	3.76e-01	-0.079900	9.32e-01
REACTOME TRANSCRIPTIONAL REGULATION BY TP53	351	3.78e-01	0.027400	9.32e-01
REACTOME PLASMA LIPOPROTEIN CLEARANCE	37	3.78e-01	0.083700	9.32e-01
REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS	42	3.78e-01	-0.078600	9.32e-01
REACTOME RHOBTB1 GTPASE CYCLE	22	3.79e-01	0.108000	9.32e-01
REACTOME CITRIC ACID CYCLE TCA CYCLE	21	3.79e-01	0.111000	9.32e-01
REACTOME ONCOGENIC MAPK SIGNALING	79	3.79e-01	0.057300	9.32e-01
REACTOME MET RECEPTOR RECYCLING	10	3.80e-01	0.160000	9.32e-01
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION	1356	3.81e-01	0.014200	9.32e-01
REACTOME JOSEPHIN DOMAIN DUBS	11	3.81e-01	0.153000	9.32e-01
REACTOME MITOPHAGY	28	3.81e-01	0.095600	9.32e-01
REACTOME SENSORY PERCEPTION OF SALTY TASTE	6	3.81e-01	-0.206000	9.32e-01
REACTOME REGULATION OF BACH1 ACTIVITY	11	3.81e-01	-0.152000	9.32e-01
REACTOME PECAM1 INTERACTIONS	12	3.81e-01	0.146000	9.32e-01
REACTOME DAP12 INTERACTIONS	37	3.81e-01	-0.083200	9.32e-01
REACTOME POLYMERASE SWITCHING	13	3.81e-01	0.140000	9.32e-01
REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	31	3.82e-01	0.090700	9.32e-01
REACTOME MRNA EDITING C TO U CONVERSION	8	3.83e-01	0.178000	9.32e-01
REACTOME TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX	14	3.83e-01	-0.135000	9.32e-01
REACTOME CREB PHOSPHORYLATION	6	3.83e-01	-0.206000	9.32e-01
REACTOME ACETYLCHOLINE REGULATES INSULIN SECRETION	10	3.83e-01	-0.159000	9.32e-01
REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	12	3.84e-01	0.145000	9.32e-01
REACTOME PLASMA LIPOPROTEIN REMODELING	33	3.84e-01	0.087500	9.32e-01
REACTOME CARDIAC CONDUCTION	125	3.85e-01	0.045000	9.32e-01
REACTOME ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY	10	3.86e-01	0.158000	9.32e-01
REACTOME CIRCADIAN CLOCK	68	3.86e-01	-0.060700	9.32e-01
REACTOME SUMOYLATION OF IMMUNE RESPONSE PROTEINS	10	3.87e-01	0.158000	9.32e-01
REACTOME ZINC TRANSPORTERS	15	3.87e-01	0.129000	9.32e-01
REACTOME RMTS METHYLATE HISTONE ARGININES	72	3.89e-01	0.058700	9.32e-01
REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS	8	3.89e-01	-0.176000	9.32e-01
REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ	6	3.89e-01	0.203000	9.32e-01
REACTOME TELOMERE C STRAND LAGGING STRAND SYNTHESIS	33	3.89e-01	0.086600	9.32e-01
REACTOME P75NTR REGULATES AXONOGENESIS	9	3.89e-01	0.166000	9.32e-01
REACTOME SIGNALING BY NOTCH	234	3.90e-01	0.032600	9.33e-01
REACTOME BICARBONATE TRANSPORTERS	10	3.93e-01	-0.156000	9.34e-01
REACTOME REDUCTION OF CYTOSOLIC CA LEVELS	11	3.93e-01	0.149000	9.34e-01
REACTOME TRAIL SIGNALING	8	3.94e-01	-0.174000	9.34e-01
REACTOME HDL ASSEMBLY	8	3.95e-01	0.174000	9.34e-01
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM	688	3.95e-01	0.019000	9.34e-01
REACTOME EXTRACELLULAR MATRIX ORGANIZATION	291	3.95e-01	-0.029000	9.34e-01
REACTOME SYNTHESIS OF GDP MANNOSE	5	3.96e-01	0.219000	9.34e-01
REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4	33	3.97e-01	0.085200	9.34e-01
REACTOME NTRK2 ACTIVATES RAC1	5	3.98e-01	0.218000	9.34e-01
REACTOME ANCHORING FIBRIL FORMATION	13	3.98e-01	0.135000	9.34e-01
REACTOME UNFOLDED PROTEIN RESPONSE UPR	88	3.98e-01	0.052100	9.34e-01
REACTOME PROLONGED ERK ACTIVATION EVENTS	14	3.98e-01	0.130000	9.34e-01
REACTOME COLLAGEN DEGRADATION	61	3.99e-01	-0.062500	9.34e-01
REACTOME SCAVENGING OF HEME FROM PLASMA	13	3.99e-01	-0.135000	9.34e-01
REACTOME INTERLEUKIN 15 SIGNALING	13	3.99e-01	-0.135000	9.34e-01
REACTOME HOST INTERACTIONS OF HIV FACTORS	127	4.00e-01	0.043200	9.35e-01
REACTOME DEGRADATION OF AXIN	54	4.02e-01	0.065900	9.36e-01
REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	19	4.04e-01	-0.111000	9.36e-01
REACTOME REGULATED NECROSIS	57	4.04e-01	-0.063900	9.36e-01
REACTOME COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM	21	4.04e-01	-0.105000	9.36e-01
REACTOME PYRIMIDINE CATABOLISM	12	4.04e-01	0.139000	9.36e-01
REACTOME HEDGEHOG LIGAND BIOGENESIS	64	4.05e-01	0.060200	9.36e-01
REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL	12	4.05e-01	0.139000	9.36e-01
REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION	12	4.05e-01	0.139000	9.36e-01
REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	91	4.06e-01	-0.050400	9.37e-01
REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	51	4.07e-01	-0.067100	9.37e-01
REACTOME SULFIDE OXIDATION TO SULFATE	6	4.08e-01	0.195000	9.37e-01
REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	14	4.08e-01	0.128000	9.37e-01
REACTOME G ALPHA Q SIGNALLING EVENTS	206	4.09e-01	-0.033400	9.37e-01
REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	16	4.10e-01	0.119000	9.37e-01
REACTOME TIGHT JUNCTION INTERACTIONS	29	4.10e-01	0.088300	9.37e-01
REACTOME TOXICITY OF BOTULINUM TOXIN TYPE D BOTD	5	4.10e-01	0.213000	9.37e-01
REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	80	4.12e-01	0.053100	9.37e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD4	15	4.12e-01	-0.122000	9.37e-01
REACTOME REGULATION OF PTEN GENE TRANSCRIPTION	59	4.12e-01	0.061700	9.37e-01
REACTOME TERMINATION OF TRANSLESION DNA SYNTHESIS	32	4.13e-01	0.083600	9.37e-01
REACTOME METABOLISM OF FOLATE AND PTERINES	17	4.14e-01	0.114000	9.37e-01
REACTOME DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA	77	4.14e-01	-0.053900	9.37e-01
REACTOME NUCLEAR SIGNALING BY ERBB4	32	4.14e-01	-0.083400	9.37e-01
REACTOME NUCLEAR PORE COMPLEX NPC DISASSEMBLY	36	4.16e-01	-0.078400	9.37e-01
REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS	5	4.17e-01	-0.210000	9.37e-01
REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING	6	4.19e-01	0.191000	9.37e-01
REACTOME SIGNALING BY FGFR1 IN DISEASE	38	4.19e-01	0.075700	9.37e-01
REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	12	4.20e-01	-0.135000	9.37e-01
REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES	34	4.20e-01	-0.079900	9.37e-01
REACTOME PROPIONYL COA CATABOLISM	5	4.20e-01	-0.208000	9.37e-01
REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	11	4.21e-01	0.140000	9.37e-01
REACTOME PTK6 EXPRESSION	5	4.23e-01	0.207000	9.37e-01
REACTOME TRNA PROCESSING IN THE NUCLEUS	58	4.23e-01	0.060800	9.37e-01
REACTOME HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS	9	4.23e-01	-0.154000	9.37e-01
REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE	71	4.24e-01	0.054900	9.37e-01
REACTOME PROGRAMMED CELL DEATH	204	4.24e-01	-0.032500	9.37e-01
REACTOME METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS	122	4.24e-01	-0.041900	9.37e-01
REACTOME REGULATION OF PTEN MRNA TRANSLATION	9	4.24e-01	0.154000	9.37e-01
REACTOME PKA ACTIVATION IN GLUCAGON SIGNALLING	17	4.26e-01	-0.112000	9.37e-01
REACTOME NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	24	4.26e-01	-0.093800	9.37e-01
REACTOME RHO GTPASES ACTIVATE CIT	19	4.27e-01	-0.105000	9.37e-01
REACTOME HDR THROUGH MMEJ ALT NHEJ	12	4.27e-01	-0.132000	9.37e-01
REACTOME TYROSINE CATABOLISM	5	4.30e-01	0.204000	9.37e-01
REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX	9	4.30e-01	0.152000	9.37e-01
REACTOME FORMATION OF PARAXIAL MESODERM	22	4.30e-01	0.097200	9.37e-01
REACTOME TP53 REGULATES METABOLIC GENES	81	4.31e-01	0.050600	9.37e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS	15	4.32e-01	0.117000	9.37e-01
REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	12	4.33e-01	0.131000	9.37e-01
REACTOME LAMININ INTERACTIONS	28	4.33e-01	-0.085600	9.37e-01
REACTOME RHO GTPASES ACTIVATE KTN1	11	4.33e-01	-0.136000	9.37e-01
REACTOME INWARDLY RECTIFYING K CHANNELS	35	4.33e-01	0.076500	9.37e-01
REACTOME REGULATION OF TP53 EXPRESSION AND DEGRADATION	37	4.34e-01	0.074300	9.37e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING	5	4.34e-01	0.202000	9.37e-01
REACTOME G2 M CHECKPOINTS	162	4.35e-01	0.035600	9.37e-01
REACTOME ION HOMEOSTASIS	52	4.36e-01	0.062500	9.37e-01
REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS	63	4.36e-01	0.056700	9.37e-01
REACTOME DEFECTIVE GALNT3 CAUSES HFTC	16	4.36e-01	-0.112000	9.37e-01
REACTOME MAP2K AND MAPK ACTIVATION	38	4.36e-01	0.073000	9.37e-01
REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	11	4.37e-01	-0.135000	9.37e-01
REACTOME SIGNALING BY FLT3 ITD AND TKD MUTANTS	16	4.37e-01	0.112000	9.37e-01
REACTOME APOPTOTIC FACTOR MEDIATED RESPONSE	19	4.38e-01	0.103000	9.37e-01
REACTOME HDR THROUGH SINGLE STRAND ANNEALING SSA	37	4.39e-01	-0.073600	9.37e-01
REACTOME BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS	10	4.39e-01	-0.141000	9.37e-01
REACTOME RAS PROCESSING	22	4.39e-01	0.095300	9.37e-01
REACTOME MITOTIC G2 G2 M PHASES	194	4.40e-01	0.032200	9.37e-01
REACTOME P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1	6	4.41e-01	0.182000	9.37e-01
REACTOME PROLACTIN RECEPTOR SIGNALING	15	4.41e-01	-0.115000	9.37e-01
REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	98	4.41e-01	0.045000	9.37e-01
REACTOME REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS	15	4.41e-01	-0.115000	9.37e-01
REACTOME INTERLEUKIN 1 SIGNALING	110	4.41e-01	0.042500	9.37e-01
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION	361	4.43e-01	-0.023500	9.39e-01
REACTOME CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION	11	4.46e-01	-0.133000	9.42e-01
REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	35	4.46e-01	-0.074400	9.42e-01
REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	15	4.46e-01	-0.114000	9.42e-01
REACTOME TRIGLYCERIDE BIOSYNTHESIS	12	4.47e-01	-0.127000	9.42e-01
REACTOME STABILIZATION OF P53	56	4.47e-01	0.058700	9.42e-01
REACTOME POST TRANSCRIPTIONAL SILENCING BY SMALL RNAS	7	4.47e-01	0.166000	9.42e-01
REACTOME MET ACTIVATES PTK2 SIGNALING	30	4.50e-01	-0.079800	9.42e-01
REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	52	4.50e-01	0.060600	9.42e-01
REACTOME UPTAKE OF DIETARY COBALAMINS INTO ENTEROCYTES	9	4.51e-01	0.145000	9.42e-01
REACTOME ACTIVATION OF RAS IN B CELLS	5	4.51e-01	-0.195000	9.42e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS	5	4.52e-01	-0.194000	9.42e-01
REACTOME INNATE IMMUNE SYSTEM	1002	4.52e-01	0.014000	9.42e-01
REACTOME DNA DOUBLE STRAND BREAK REPAIR	162	4.52e-01	0.034200	9.42e-01
REACTOME COENZYME A BIOSYNTHESIS	8	4.52e-01	0.153000	9.42e-01
REACTOME DNA REPLICATION INITIATION	7	4.53e-01	0.164000	9.42e-01
REACTOME NUCLEOTIDE BIOSYNTHESIS	14	4.54e-01	0.116000	9.42e-01
REACTOME RHO GTPASES ACTIVATE NADPH OXIDASES	21	4.55e-01	0.094300	9.42e-01
REACTOME FERTILIZATION	26	4.55e-01	0.084700	9.42e-01
REACTOME CONJUGATION OF BENZOATE WITH GLYCINE	6	4.56e-01	-0.176000	9.42e-01
REACTOME ACTIVATION OF CASPASES THROUGH APOPTOSOME MEDIATED CLEAVAGE	5	4.56e-01	-0.193000	9.42e-01
REACTOME INTEGRIN SIGNALING	27	4.56e-01	0.082800	9.42e-01
REACTOME CAMK IV MEDIATED PHOSPHORYLATION OF CREB	10	4.58e-01	0.136000	9.43e-01
REACTOME SUMOYLATION	179	4.59e-01	-0.032100	9.43e-01
REACTOME AZATHIOPRINE ADME	22	4.59e-01	0.091200	9.43e-01
REACTOME SHC1 EVENTS IN EGFR SIGNALING	14	4.60e-01	-0.114000	9.43e-01
REACTOME O LINKED GLYCOSYLATION	109	4.60e-01	-0.041000	9.43e-01
REACTOME DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A	5	4.60e-01	-0.191000	9.43e-01
REACTOME ACYL CHAIN REMODELLING OF PC	27	4.60e-01	0.082100	9.43e-01
REACTOME NOD1 2 SIGNALING PATHWAY	33	4.61e-01	0.074100	9.44e-01
REACTOME VITAMINS	6	4.64e-01	0.172000	9.47e-01
REACTOME CROSSLINKING OF COLLAGEN FIBRILS	16	4.65e-01	0.106000	9.47e-01
REACTOME SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS	74	4.66e-01	-0.049000	9.47e-01
REACTOME HIV TRANSCRIPTION INITIATION	43	4.66e-01	0.064300	9.47e-01
REACTOME SYNTHESIS OF DNA	119	4.66e-01	0.038700	9.47e-01
REACTOME CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS	100	4.67e-01	-0.042100	9.47e-01
REACTOME TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS	43	4.68e-01	0.064000	9.47e-01
REACTOME RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX	29	4.69e-01	0.077700	9.47e-01
REACTOME SYNDECAN INTERACTIONS	26	4.70e-01	-0.081900	9.47e-01
REACTOME RRNA PROCESSING IN THE MITOCHONDRION	9	4.71e-01	-0.139000	9.47e-01
REACTOME NOSTRIN MEDIATED ENOS TRAFFICKING	5	4.72e-01	0.186000	9.47e-01
REACTOME TCR SIGNALING	113	4.73e-01	0.039100	9.47e-01
REACTOME RHO GTPASE CYCLE	423	4.74e-01	-0.020300	9.47e-01
REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	13	4.74e-01	0.115000	9.47e-01
REACTOME ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS	20	4.75e-01	-0.092200	9.47e-01
REACTOME REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS	7	4.76e-01	0.155000	9.47e-01
REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	73	4.77e-01	0.048100	9.47e-01
REACTOME PHOSPHORYLATION OF EMI1	6	4.77e-01	0.168000	9.47e-01
REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF	53	4.77e-01	-0.056400	9.47e-01
REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	11	4.77e-01	0.124000	9.47e-01
REACTOME POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION	27	4.78e-01	0.078900	9.47e-01
REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	14	4.79e-01	-0.109000	9.47e-01
REACTOME SIGNALING BY VEGF	102	4.79e-01	0.040600	9.47e-01
REACTOME PROCESSING OF DNA DOUBLE STRAND BREAK ENDS	93	4.79e-01	0.042400	9.47e-01
REACTOME EXTENSION OF TELOMERES	49	4.79e-01	0.058400	9.47e-01
REACTOME REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO	10	4.80e-01	-0.129000	9.47e-01
REACTOME SIGNALLING TO P38 VIA RIT AND RIN	5	4.80e-01	0.182000	9.47e-01
REACTOME PHASE 0 RAPID DEPOLARISATION	31	4.81e-01	-0.073100	9.47e-01
REACTOME PRC2 METHYLATES HISTONES AND DNA	65	4.81e-01	0.050600	9.47e-01
REACTOME MUSCARINIC ACETYLCHOLINE RECEPTORS	5	4.82e-01	0.182000	9.47e-01
REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION	23	4.82e-01	0.084700	9.47e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS	6	4.82e-01	0.166000	9.47e-01
REACTOME SYNTHESIS OF PIPS AT THE ER MEMBRANE	5	4.83e-01	-0.181000	9.47e-01
REACTOME ORC1 REMOVAL FROM CHROMATIN	70	4.83e-01	0.048500	9.47e-01
REACTOME METABOLISM OF STEROID HORMONES	35	4.84e-01	0.068400	9.47e-01
REACTOME REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR	11	4.84e-01	0.122000	9.47e-01
REACTOME CYP2E1 REACTIONS	10	4.85e-01	-0.128000	9.47e-01
REACTOME TRANSLESION SYNTHESIS BY POLK	17	4.85e-01	-0.097800	9.47e-01
REACTOME RUNX2 REGULATES CHONDROCYTE MATURATION	5	4.87e-01	-0.179000	9.47e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS	7	4.87e-01	0.152000	9.47e-01
REACTOME ALK MUTANTS BIND TKIS	12	4.87e-01	-0.116000	9.47e-01
REACTOME AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY	8	4.88e-01	0.142000	9.47e-01
REACTOME METABOLISM OF FAT SOLUBLE VITAMINS	46	4.88e-01	0.059100	9.47e-01
REACTOME MEIOSIS	110	4.89e-01	0.038200	9.47e-01
REACTOME SYNTHESIS OF 15 EICOSATETRAENOIC ACID DERIVATIVES	6	4.90e-01	-0.163000	9.47e-01
REACTOME RIP MEDIATED NFKB ACTIVATION VIA ZBP1	16	4.90e-01	0.099700	9.47e-01
REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS	68	4.90e-01	-0.048400	9.47e-01
REACTOME APEX1 INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	7	4.91e-01	0.150000	9.47e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	28	4.91e-01	0.075100	9.47e-01
REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	54	4.92e-01	0.054000	9.47e-01
REACTOME ACYL CHAIN REMODELLING OF PS	22	4.94e-01	0.084300	9.49e-01
REACTOME RAS SIGNALING DOWNSTREAM OF NF1 LOSS OF FUNCTION VARIANTS	7	4.95e-01	0.149000	9.49e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST	18	4.95e-01	-0.092900	9.49e-01
REACTOME G2 PHASE	5	4.95e-01	-0.176000	9.49e-01
REACTOME HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS	7	4.97e-01	-0.148000	9.50e-01
REACTOME GPER1 SIGNALING	45	4.97e-01	-0.058500	9.50e-01
REACTOME PI5P REGULATES TP53 ACETYLATION	9	4.98e-01	-0.131000	9.50e-01
REACTOME INTERLEUKIN 10 SIGNALING	43	4.99e-01	0.059600	9.50e-01
REACTOME TRIGLYCERIDE CATABOLISM	23	4.99e-01	0.081400	9.50e-01
REACTOME PHENYLALANINE AND TYROSINE METABOLISM	11	4.99e-01	0.118000	9.50e-01
REACTOME GENERATION OF SECOND MESSENGER MOLECULES	30	5.01e-01	0.071000	9.52e-01
REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	16	5.02e-01	-0.096900	9.54e-01
REACTOME P2Y RECEPTORS	9	5.03e-01	0.129000	9.54e-01
REACTOME MITOTIC TELOPHASE CYTOKINESIS	11	5.04e-01	-0.116000	9.55e-01
REACTOME MISCELLANEOUS TRANSPORT AND BINDING EVENTS	24	5.06e-01	-0.078400	9.56e-01
REACTOME COHESIN LOADING ONTO CHROMATIN	8	5.08e-01	-0.135000	9.56e-01
REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS	83	5.11e-01	0.041800	9.56e-01
REACTOME MATURATION OF PROTEIN 3A	9	5.11e-01	-0.126000	9.56e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	25	5.11e-01	0.075900	9.56e-01
REACTOME CLEC7A DECTIN 1 SIGNALING	97	5.12e-01	0.038500	9.56e-01
REACTOME SIGNALING BY GPCR	673	5.12e-01	-0.014800	9.56e-01
REACTOME ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN	13	5.13e-01	-0.105000	9.56e-01
REACTOME TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE	20	5.14e-01	0.084400	9.56e-01
REACTOME SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL	8	5.14e-01	0.133000	9.56e-01
REACTOME E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS	58	5.14e-01	0.049600	9.56e-01
REACTOME INTERLEUKIN 12 SIGNALING	43	5.14e-01	0.057500	9.56e-01
REACTOME FLT3 SIGNALING BY CBL MUTANTS	7	5.15e-01	0.142000	9.56e-01
REACTOME CELL JUNCTION ORGANIZATION	89	5.15e-01	-0.039900	9.56e-01
REACTOME RAF INDEPENDENT MAPK1 3 ACTIVATION	22	5.16e-01	0.080100	9.56e-01
REACTOME FLT3 SIGNALING THROUGH SRC FAMILY KINASES	6	5.16e-01	0.153000	9.56e-01
REACTOME MODULATION BY MTB OF HOST IMMUNE SYSTEM	6	5.16e-01	0.153000	9.56e-01
REACTOME DAG AND IP3 SIGNALING	40	5.16e-01	-0.059300	9.56e-01
REACTOME CARNITINE METABOLISM	13	5.18e-01	-0.104000	9.56e-01
REACTOME NONCANONICAL ACTIVATION OF NOTCH3	8	5.19e-01	0.132000	9.56e-01
REACTOME HS GAG DEGRADATION	19	5.23e-01	0.084600	9.56e-01
REACTOME INTRAFLAGELLAR TRANSPORT	50	5.23e-01	-0.052200	9.56e-01
REACTOME INTERFERON GAMMA SIGNALING	88	5.23e-01	-0.039400	9.56e-01
REACTOME TRAF6 MEDIATED NF KB ACTIVATION	24	5.24e-01	-0.075200	9.56e-01
REACTOME CHREBP ACTIVATES METABOLIC GENE EXPRESSION	8	5.25e-01	0.130000	9.56e-01
REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	13	5.25e-01	0.102000	9.56e-01
REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	22	5.26e-01	-0.078200	9.56e-01
REACTOME INTERLEUKIN 1 FAMILY SIGNALING	146	5.26e-01	0.030400	9.56e-01
REACTOME SIGNALING BY KIT IN DISEASE	20	5.26e-01	-0.081800	9.56e-01
REACTOME BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA	5	5.27e-01	0.163000	9.56e-01
REACTOME INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE	20	5.27e-01	0.081800	9.56e-01
REACTOME SIGNALING BY RNF43 MUTANTS	8	5.29e-01	0.128000	9.56e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER	28	5.30e-01	0.068600	9.56e-01
REACTOME RHO GTPASES ACTIVATE PKNS	86	5.30e-01	0.039100	9.56e-01
REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	13	5.31e-01	0.100000	9.56e-01
REACTOME FORMATION OF LATERAL PLATE MESODERM	5	5.35e-01	0.160000	9.56e-01
REACTOME RSK ACTIVATION	5	5.35e-01	0.160000	9.56e-01
REACTOME VIRAL MESSENGER RNA SYNTHESIS	44	5.36e-01	0.054000	9.56e-01
REACTOME SIGNALLING TO ERKS	34	5.36e-01	0.061300	9.56e-01
REACTOME CALNEXIN CALRETICULIN CYCLE	26	5.37e-01	-0.070000	9.56e-01
REACTOME NEUROTOXICITY OF CLOSTRIDIUM TOXINS	10	5.38e-01	0.113000	9.56e-01
REACTOME ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE	9	5.38e-01	-0.119000	9.56e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION TERMINATION	23	5.39e-01	0.074100	9.56e-01
REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	26	5.40e-01	0.069500	9.56e-01
REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS	16	5.40e-01	-0.088500	9.56e-01
REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS	28	5.40e-01	-0.066900	9.56e-01
REACTOME MAPK3 ERK1 ACTIVATION	10	5.40e-01	0.112000	9.56e-01
REACTOME RAP1 SIGNALLING	16	5.41e-01	0.088400	9.56e-01
REACTOME DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS	19	5.41e-01	0.081100	9.56e-01
REACTOME ASPARTATE AND ASPARAGINE METABOLISM	11	5.41e-01	0.106000	9.56e-01
REACTOME CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY	12	5.41e-01	0.102000	9.56e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE	20	5.41e-01	-0.078900	9.56e-01
REACTOME NS1 MEDIATED EFFECTS ON HOST PATHWAYS	41	5.42e-01	-0.055000	9.56e-01
REACTOME RHOT1 GTPASE CYCLE	5	5.45e-01	0.156000	9.56e-01
REACTOME IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS	17	5.45e-01	0.084700	9.56e-01
REACTOME NICOTINATE METABOLISM	31	5.46e-01	-0.062700	9.56e-01
REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	20	5.47e-01	-0.077800	9.56e-01
REACTOME DNA DAMAGE REVERSAL	8	5.48e-01	-0.123000	9.56e-01
REACTOME ACYL CHAIN REMODELLING OF PG	18	5.49e-01	0.081600	9.56e-01
REACTOME DNA DAMAGE BYPASS	47	5.50e-01	0.050400	9.56e-01
REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	8	5.50e-01	0.122000	9.56e-01
REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS	16	5.52e-01	-0.085900	9.56e-01
REACTOME DISORDERS OF TRANSMEMBRANE TRANSPORTERS	170	5.53e-01	0.026400	9.56e-01
REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	13	5.53e-01	-0.095000	9.56e-01
REACTOME CELL CELL JUNCTION ORGANIZATION	64	5.53e-01	-0.042800	9.56e-01
REACTOME CHYLOMICRON ASSEMBLY	10	5.54e-01	-0.108000	9.56e-01
REACTOME ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS	24	5.54e-01	-0.069800	9.56e-01
REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES	34	5.55e-01	-0.058400	9.56e-01
REACTOME EGFR INTERACTS WITH PHOSPHOLIPASE C GAMMA	9	5.57e-01	-0.113000	9.56e-01
REACTOME EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION	27	5.58e-01	-0.065100	9.56e-01
REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS	83	5.59e-01	-0.037100	9.56e-01
REACTOME SMALL INTERFERING RNA SIRNA BIOGENESIS	9	5.59e-01	0.113000	9.56e-01
REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	57	5.59e-01	0.044700	9.56e-01
REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	9	5.60e-01	-0.112000	9.56e-01
REACTOME FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS	8	5.60e-01	-0.119000	9.56e-01
REACTOME GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER	25	5.60e-01	0.067300	9.56e-01
REACTOME CA2 PATHWAY	62	5.61e-01	0.042700	9.56e-01
REACTOME INTERLEUKIN 27 SIGNALING	11	5.61e-01	-0.101000	9.56e-01
REACTOME REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE	81	5.62e-01	0.037300	9.56e-01
REACTOME LYSOSPHINGOLIPID AND LPA RECEPTORS	14	5.62e-01	0.089400	9.56e-01
REACTOME RHOBTB3 ATPASE CYCLE	8	5.62e-01	0.118000	9.56e-01
REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION	19	5.63e-01	0.076700	9.56e-01
REACTOME CRISTAE FORMATION	27	5.63e-01	0.064300	9.56e-01
REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	16	5.63e-01	0.083400	9.56e-01
REACTOME UPTAKE AND FUNCTION OF ANTHRAX TOXINS	11	5.64e-01	-0.100000	9.56e-01
REACTOME MITOCHONDRIAL CALCIUM ION TRANSPORT	23	5.64e-01	0.069500	9.56e-01
REACTOME NETRIN MEDIATED REPULSION SIGNALS	8	5.65e-01	-0.117000	9.56e-01
REACTOME INFECTION WITH MYCOBACTERIUM TUBERCULOSIS	25	5.65e-01	0.066500	9.56e-01
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES	255	5.67e-01	0.020800	9.56e-01
REACTOME EPH EPHRIN MEDIATED REPULSION OF CELLS	50	5.67e-01	0.046800	9.56e-01
REACTOME SODIUM PROTON EXCHANGERS	7	5.67e-01	-0.125000	9.56e-01
REACTOME PROCESSING OF SMDT1	16	5.67e-01	0.082600	9.56e-01
REACTOME DOWNREGULATION OF ERBB4 SIGNALING	9	5.68e-01	-0.110000	9.56e-01
REACTOME DRUG MEDIATED INHIBITION OF CDK4 CDK6 ACTIVITY	5	5.69e-01	0.147000	9.56e-01
REACTOME PI3K EVENTS IN ERBB4 SIGNALING	10	5.70e-01	-0.104000	9.56e-01
REACTOME METABOLISM OF CARBOHYDRATES	279	5.70e-01	0.019800	9.56e-01
REACTOME ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES	59	5.71e-01	-0.042700	9.56e-01
REACTOME VITAMIN D CALCIFEROL METABOLISM	12	5.71e-01	-0.094400	9.56e-01
REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	20	5.72e-01	0.073000	9.56e-01
REACTOME HISTIDINE CATABOLISM	8	5.72e-01	-0.115000	9.56e-01
REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	9	5.73e-01	0.109000	9.56e-01
REACTOME SIGNALING BY MAPK MUTANTS	6	5.73e-01	-0.133000	9.56e-01
REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	24	5.73e-01	-0.066400	9.56e-01
REACTOME ECM PROTEOGLYCANS	73	5.75e-01	-0.038000	9.56e-01
REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	18	5.75e-01	0.076300	9.56e-01
REACTOME FORMATION OF XYLULOSE 5 PHOSPHATE	5	5.77e-01	-0.144000	9.56e-01
REACTOME ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS	7	5.77e-01	0.122000	9.56e-01
REACTOME FLT3 SIGNALING IN DISEASE	28	5.77e-01	0.060900	9.56e-01
REACTOME LDL REMODELING	6	5.77e-01	-0.131000	9.56e-01
REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	16	5.78e-01	-0.080300	9.56e-01
REACTOME INTERLEUKIN 37 SIGNALING	20	5.79e-01	0.071700	9.56e-01
REACTOME TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY	30	5.81e-01	0.058200	9.56e-01
REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	26	5.81e-01	0.062500	9.56e-01
REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	10	5.81e-01	-0.101000	9.56e-01
REACTOME PEPTIDE HORMONE BIOSYNTHESIS	13	5.83e-01	0.087900	9.56e-01
REACTOME GRB7 EVENTS IN ERBB2 SIGNALING	5	5.83e-01	0.142000	9.56e-01
REACTOME PEPTIDE HORMONE METABOLISM	84	5.84e-01	0.034600	9.56e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH PI3K	6	5.84e-01	0.129000	9.56e-01
REACTOME APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS	87	5.86e-01	0.033700	9.56e-01
REACTOME ATTACHMENT AND ENTRY	16	5.87e-01	0.078300	9.56e-01
REACTOME ALPHA OXIDATION OF PHYTANATE	6	5.88e-01	0.128000	9.56e-01
REACTOME SIGNALING BY LRP5 MUTANTS	6	5.88e-01	0.128000	9.56e-01
REACTOME WAX AND PLASMALOGEN BIOSYNTHESIS	5	5.89e-01	0.139000	9.56e-01
REACTOME TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE	39	5.89e-01	0.049900	9.56e-01
REACTOME RNA POLYMERASE II PRE TRANSCRIPTION EVENTS	77	5.90e-01	0.035500	9.56e-01
REACTOME CHYLOMICRON CLEARANCE	5	5.90e-01	-0.139000	9.56e-01
REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	99	5.91e-01	0.031300	9.56e-01
REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	30	5.91e-01	-0.056700	9.56e-01
REACTOME KEAP1 NFE2L2 PATHWAY	104	5.92e-01	-0.030400	9.56e-01
REACTOME SIGNALING BY ALK	26	5.92e-01	0.060600	9.56e-01
REACTOME UPTAKE AND ACTIONS OF BACTERIAL TOXINS	28	5.93e-01	-0.058300	9.56e-01
REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY	26	5.93e-01	0.060500	9.56e-01
REACTOME CELL CELL COMMUNICATION	126	5.94e-01	-0.027500	9.56e-01
REACTOME TRANSPORT OF ORGANIC ANIONS	10	5.94e-01	0.097300	9.56e-01
REACTOME SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE	91	5.95e-01	0.032300	9.56e-01
REACTOME FORMATION OF APOPTOSOME	10	5.95e-01	0.097000	9.56e-01
REACTOME CHAPERONE MEDIATED AUTOPHAGY	20	5.96e-01	0.068600	9.56e-01
REACTOME GABA B RECEPTOR ACTIVATION	43	5.96e-01	0.046700	9.56e-01
REACTOME REGULATION OF MECP2 EXPRESSION AND ACTIVITY	30	5.96e-01	0.055900	9.56e-01
REACTOME ATTACHMENT OF GPI ANCHOR TO UPAR	7	5.97e-01	-0.115000	9.56e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY DVL INTERACTING PROTEINS	5	5.97e-01	-0.136000	9.56e-01
REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING	45	5.98e-01	0.045400	9.56e-01
REACTOME TYSND1 CLEAVES PEROXISOMAL PROTEINS	7	5.98e-01	0.115000	9.56e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	14	5.99e-01	-0.081200	9.56e-01
REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM	50	5.99e-01	-0.042900	9.56e-01
REACTOME NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10	12	6.00e-01	-0.087500	9.56e-01
REACTOME STIMULI SENSING CHANNELS	100	6.00e-01	0.030300	9.56e-01
REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	14	6.00e-01	-0.080900	9.56e-01
REACTOME EARLY PHASE OF HIV LIFE CYCLE	14	6.00e-01	0.080900	9.56e-01
REACTOME ACYL CHAIN REMODELING OF DAG AND TAG	5	6.01e-01	0.135000	9.56e-01
REACTOME PHASE 3 RAPID REPOLARISATION	8	6.01e-01	0.107000	9.56e-01
REACTOME HYALURONAN METABOLISM	17	6.02e-01	0.073100	9.56e-01
REACTOME IRF3 MEDIATED INDUCTION OF TYPE I IFN	13	6.02e-01	0.083500	9.56e-01
REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND	21	6.02e-01	0.065700	9.56e-01
REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE	93	6.03e-01	-0.031200	9.56e-01
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	122	6.03e-01	-0.027200	9.56e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FYN	7	6.06e-01	0.112000	9.56e-01
REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA	11	6.06e-01	0.089700	9.56e-01
REACTOME ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS	27	6.07e-01	-0.057200	9.56e-01
REACTOME MISMATCH REPAIR	15	6.07e-01	0.076700	9.56e-01
REACTOME G1 S SPECIFIC TRANSCRIPTION	28	6.07e-01	0.056100	9.56e-01
REACTOME INSULIN PROCESSING	24	6.07e-01	-0.060600	9.56e-01
REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	296	6.08e-01	-0.017300	9.56e-01
REACTOME UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN	6	6.08e-01	-0.121000	9.56e-01
REACTOME NUCLEOTIDE SALVAGE	21	6.09e-01	0.064500	9.56e-01
REACTOME FLT3 SIGNALING	38	6.09e-01	-0.047900	9.56e-01
REACTOME TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS	55	6.09e-01	-0.039800	9.56e-01
REACTOME ENDOSOMAL VACUOLAR PATHWAY	11	6.09e-01	-0.089000	9.56e-01
REACTOME MET PROMOTES CELL MOTILITY	41	6.10e-01	-0.046000	9.56e-01
REACTOME ABACAVIR ADME	9	6.11e-01	-0.098000	9.56e-01
REACTOME EPH EPHRIN SIGNALING	90	6.11e-01	0.031000	9.56e-01
REACTOME MAPK1 ERK2 ACTIVATION	9	6.11e-01	0.097800	9.56e-01
REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	118	6.12e-01	-0.027100	9.56e-01
REACTOME THE NLRP3 INFLAMMASOME	16	6.13e-01	-0.073100	9.56e-01
REACTOME SMAC XIAP REGULATED APOPTOTIC RESPONSE	7	6.13e-01	0.110000	9.56e-01
REACTOME TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX	10	6.15e-01	0.091800	9.56e-01
REACTOME ACTIVATION OF C3 AND C5	6	6.16e-01	0.118000	9.56e-01
REACTOME INTERLEUKIN 6 FAMILY SIGNALING	24	6.16e-01	0.059100	9.56e-01
REACTOME SIGNALING BY NTRK3 TRKC	17	6.16e-01	0.070200	9.56e-01
REACTOME SIALIC ACID METABOLISM	33	6.17e-01	0.050300	9.56e-01
REACTOME CARGO CONCENTRATION IN THE ER	32	6.19e-01	0.050800	9.56e-01
REACTOME G PROTEIN ACTIVATION	24	6.19e-01	0.058600	9.56e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS	9	6.20e-01	-0.095600	9.56e-01
REACTOME RHOBTB2 GTPASE CYCLE	22	6.20e-01	0.061100	9.56e-01
REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	14	6.21e-01	-0.076400	9.56e-01
REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	35	6.21e-01	0.048300	9.56e-01
REACTOME FIBRONECTIN MATRIX FORMATION	6	6.22e-01	0.116000	9.56e-01
REACTOME BUDDING AND MATURATION OF HIV VIRION	28	6.23e-01	0.053700	9.56e-01
REACTOME LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME	11	6.23e-01	0.085600	9.56e-01
REACTOME EPHB MEDIATED FORWARD SIGNALING	41	6.24e-01	0.044300	9.56e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES	11	6.24e-01	-0.085400	9.56e-01
REACTOME INTESTINAL ABSORPTION	5	6.24e-01	-0.126000	9.56e-01
REACTOME EGFR TRANSACTIVATION BY GASTRIN	9	6.24e-01	-0.094300	9.56e-01
REACTOME PEROXISOMAL LIPID METABOLISM	28	6.25e-01	-0.053400	9.56e-01
REACTOME SIGNALING BY ERYTHROPOIETIN	25	6.25e-01	0.056400	9.56e-01
REACTOME RHOBTB GTPASE CYCLE	34	6.26e-01	0.048400	9.56e-01
REACTOME SEROTONIN NEUROTRANSMITTER RELEASE CYCLE	17	6.26e-01	0.068200	9.56e-01
REACTOME DISEASES OF GLYCOSYLATION	137	6.26e-01	0.024100	9.56e-01
REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION	11	6.27e-01	0.084700	9.56e-01
REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	23	6.27e-01	-0.058500	9.56e-01
REACTOME TRANSCRIPTIONAL REGULATION BY MECP2	60	6.28e-01	0.036200	9.56e-01
REACTOME PLATELET CALCIUM HOMEOSTASIS	27	6.28e-01	-0.053800	9.56e-01
REACTOME HSF1 ACTIVATION	29	6.29e-01	0.051900	9.56e-01
REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX	13	6.29e-01	-0.077400	9.56e-01
REACTOME REGULATED PROTEOLYSIS OF P75NTR	11	6.30e-01	0.083900	9.56e-01
REACTOME SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA PHE	6	6.31e-01	0.113000	9.56e-01
REACTOME RECYCLING PATHWAY OF L1	43	6.31e-01	-0.042300	9.56e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES	12	6.31e-01	-0.080000	9.56e-01
REACTOME MYD88 INDEPENDENT TLR4 CASCADE	103	6.32e-01	0.027300	9.56e-01
REACTOME APOPTOSIS	173	6.32e-01	-0.021100	9.56e-01
REACTOME GLUCOCORTICOID BIOSYNTHESIS	10	6.32e-01	0.087400	9.56e-01
REACTOME C TYPE LECTIN RECEPTORS CLRS	136	6.34e-01	-0.023700	9.56e-01
REACTOME NUCLEAR ENVELOPE BREAKDOWN	52	6.35e-01	-0.038100	9.56e-01
REACTOME PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS	21	6.36e-01	-0.059600	9.56e-01
REACTOME CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS	19	6.36e-01	0.062700	9.56e-01
REACTOME ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING	9	6.36e-01	0.091000	9.56e-01
REACTOME CELLULAR HEXOSE TRANSPORT	21	6.37e-01	-0.059500	9.56e-01
REACTOME COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES	65	6.38e-01	-0.033800	9.56e-01
REACTOME DISEASES OF PROGRAMMED CELL DEATH	96	6.39e-01	0.027700	9.56e-01
REACTOME NEF MEDIATED CD4 DOWN REGULATION	9	6.39e-01	-0.090300	9.56e-01
REACTOME FRUCTOSE METABOLISM	7	6.39e-01	-0.102000	9.56e-01
REACTOME IRS ACTIVATION	5	6.40e-01	-0.121000	9.56e-01
REACTOME KILLING MECHANISMS	11	6.40e-01	0.081500	9.56e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE	5	6.41e-01	-0.120000	9.56e-01
REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING	29	6.41e-01	-0.050000	9.56e-01
REACTOME CONDENSATION OF PROMETAPHASE CHROMOSOMES	11	6.42e-01	0.081000	9.56e-01
REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES	78	6.42e-01	-0.030500	9.56e-01
REACTOME FCGR ACTIVATION	11	6.43e-01	-0.080600	9.56e-01
REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION	26	6.44e-01	-0.052400	9.56e-01
REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	37	6.44e-01	0.043900	9.56e-01
REACTOME CHOLINE CATABOLISM	6	6.44e-01	-0.109000	9.56e-01
REACTOME IRON UPTAKE AND TRANSPORT	56	6.44e-01	-0.035700	9.56e-01
REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	53	6.45e-01	0.036500	9.56e-01
REACTOME CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA	63	6.46e-01	0.033400	9.56e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES	49	6.47e-01	0.037900	9.56e-01
REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	48	6.47e-01	-0.038200	9.56e-01
REACTOME RAB REGULATION OF TRAFFICKING	110	6.48e-01	0.025200	9.56e-01
REACTOME EICOSANOID LIGAND BINDING RECEPTORS	14	6.48e-01	0.070500	9.56e-01
REACTOME RHOV GTPASE CYCLE	36	6.49e-01	0.043800	9.56e-01
REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	129	6.49e-01	0.023200	9.56e-01
REACTOME ARACHIDONIC ACID METABOLISM	57	6.49e-01	-0.034800	9.56e-01
REACTOME DISEASES OF BASE EXCISION REPAIR	5	6.50e-01	-0.117000	9.56e-01
REACTOME SIGNALING BY FGFR4 IN DISEASE	11	6.51e-01	0.078900	9.56e-01
REACTOME MUCOPOLYSACCHARIDOSES	10	6.51e-01	-0.082700	9.56e-01
REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	9	6.51e-01	-0.087000	9.56e-01
REACTOME SIGNALING BY ALK IN CANCER	53	6.52e-01	-0.035800	9.56e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH RAS	8	6.52e-01	0.092000	9.56e-01
REACTOME PROTON COUPLED MONOCARBOXYLATE TRANSPORT	6	6.53e-01	-0.106000	9.56e-01
REACTOME NUCLEAR IMPORT OF REV PROTEIN	34	6.53e-01	0.044500	9.56e-01
REACTOME NADE MODULATES DEATH SIGNALLING	5	6.53e-01	-0.116000	9.56e-01
REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	32	6.55e-01	-0.045600	9.56e-01
REACTOME INFLAMMASOMES	21	6.55e-01	-0.056300	9.56e-01
REACTOME NEUROTRANSMITTER RELEASE CYCLE	48	6.55e-01	0.037200	9.56e-01
REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	19	6.56e-01	0.059000	9.56e-01
REACTOME DOPAMINE RECEPTORS	5	6.57e-01	-0.115000	9.56e-01
REACTOME MEIOTIC RECOMBINATION	80	6.57e-01	0.028700	9.56e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING	25	6.58e-01	0.051200	9.56e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES	10	6.58e-01	-0.080900	9.56e-01
REACTOME KINESINS	59	6.58e-01	0.033300	9.56e-01
REACTOME PRE NOTCH EXPRESSION AND PROCESSING	112	6.58e-01	0.024200	9.56e-01
REACTOME INTERLEUKIN 2 FAMILY SIGNALING	40	6.59e-01	0.040400	9.56e-01
REACTOME SYNTHESIS OF PG	8	6.59e-01	0.090000	9.56e-01
REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	20	6.60e-01	-0.056900	9.56e-01
REACTOME SIGNALING BY THE B CELL RECEPTOR BCR	106	6.60e-01	-0.024800	9.56e-01
REACTOME MET ACTIVATES PTPN11	5	6.60e-01	0.113000	9.56e-01
REACTOME FORMATION OF INCISION COMPLEX IN GG NER	40	6.61e-01	0.040100	9.56e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY	19	6.61e-01	0.058000	9.56e-01
REACTOME HUR ELAVL1 BINDS AND STABILIZES MRNA	8	6.62e-01	0.089400	9.56e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	36	6.62e-01	-0.042000	9.56e-01
REACTOME FC EPSILON RECEPTOR FCERI SIGNALING	127	6.63e-01	0.022400	9.56e-01
REACTOME REGULATION OF RUNX1 EXPRESSION AND ACTIVITY	17	6.63e-01	0.061000	9.56e-01
REACTOME HYDROLYSIS OF LPC	9	6.64e-01	-0.083700	9.56e-01
REACTOME FRUCTOSE CATABOLISM	5	6.64e-01	-0.112000	9.56e-01
REACTOME PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING	5	6.65e-01	0.112000	9.56e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS	8	6.65e-01	0.088500	9.56e-01
REACTOME PI3K AKT ACTIVATION	9	6.67e-01	0.082800	9.56e-01
REACTOME DEADENYLATION DEPENDENT MRNA DECAY	56	6.67e-01	0.033200	9.56e-01
REACTOME ATTENUATION PHASE	27	6.69e-01	0.047600	9.56e-01
REACTOME CA DEPENDENT EVENTS	36	6.69e-01	-0.041200	9.56e-01
REACTOME SIGNALING BY HIPPO	19	6.69e-01	-0.056600	9.56e-01
REACTOME CHYLOMICRON REMODELING	10	6.70e-01	0.077700	9.56e-01
REACTOME UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION	19	6.70e-01	0.056400	9.56e-01
REACTOME RUNX3 REGULATES BCL2L11 BIM TRANSCRIPTION	5	6.71e-01	-0.110000	9.56e-01
REACTOME SUMOYLATION OF INTRACELLULAR RECEPTORS	29	6.71e-01	-0.045600	9.56e-01
REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE	5	6.71e-01	-0.110000	9.56e-01
REACTOME DISEASES ASSOCIATED WITH SURFACTANT METABOLISM	9	6.72e-01	0.081600	9.56e-01
REACTOME INTERLEUKIN 36 PATHWAY	7	6.72e-01	-0.092300	9.56e-01
REACTOME TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY	16	6.73e-01	0.060900	9.56e-01
REACTOME SYNTHESIS OF KETONE BODIES	8	6.73e-01	-0.086200	9.56e-01
REACTOME SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX	15	6.74e-01	-0.062800	9.56e-01
REACTOME RRNA MODIFICATION IN THE MITOCHONDRION	6	6.74e-01	0.099000	9.56e-01
REACTOME GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION	7	6.76e-01	0.091200	9.58e-01
REACTOME HEDGEHOG ON STATE	85	6.78e-01	0.026100	9.58e-01
REACTOME FORMATION OF THE CORNIFIED ENVELOPE	125	6.78e-01	0.021500	9.58e-01
REACTOME INTERLEUKIN 21 SIGNALING	9	6.78e-01	0.079900	9.58e-01
REACTOME DIGESTION OF DIETARY CARBOHYDRATE	6	6.79e-01	0.097600	9.58e-01
REACTOME PLATELET AGGREGATION PLUG FORMATION	39	6.80e-01	0.038200	9.59e-01
REACTOME SIGNAL ATTENUATION	10	6.80e-01	0.075200	9.59e-01
REACTOME PYRIMIDINE SALVAGE	10	6.82e-01	-0.074900	9.60e-01
REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	44	6.83e-01	0.035500	9.60e-01
REACTOME SIGNALING BY SCF KIT	42	6.83e-01	-0.036400	9.60e-01
REACTOME FANCONI ANEMIA PATHWAY	35	6.84e-01	0.039800	9.60e-01
REACTOME GABA RECEPTOR ACTIVATION	57	6.84e-01	0.031200	9.60e-01
REACTOME UREA CYCLE	9	6.84e-01	-0.078200	9.60e-01
REACTOME ACYL CHAIN REMODELLING OF PI	17	6.86e-01	0.056600	9.60e-01
REACTOME TRP CHANNELS	27	6.86e-01	0.044900	9.60e-01
REACTOME G2 M DNA DAMAGE CHECKPOINT	90	6.86e-01	0.024600	9.60e-01
REACTOME ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS	11	6.89e-01	0.069700	9.62e-01
REACTOME PERK REGULATES GENE EXPRESSION	31	6.89e-01	-0.041500	9.62e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES	29	6.90e-01	0.042800	9.62e-01
REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE	109	6.91e-01	0.022100	9.63e-01
REACTOME REGULATION OF PTEN LOCALIZATION	8	6.92e-01	0.081000	9.63e-01
REACTOME NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS	25	6.92e-01	-0.045700	9.63e-01
REACTOME DEFECTS IN VITAMIN AND COFACTOR METABOLISM	21	6.93e-01	-0.049800	9.63e-01
REACTOME VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS	42	6.93e-01	0.035200	9.63e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION	41	6.94e-01	0.035500	9.63e-01
REACTOME LATE ENDOSOMAL MICROAUTOPHAGY	33	6.95e-01	0.039400	9.64e-01
REACTOME ACTIVATION OF SMO	18	6.95e-01	-0.053300	9.64e-01
REACTOME SUPPRESSION OF APOPTOSIS	7	6.97e-01	0.085100	9.64e-01
REACTOME COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC	52	6.97e-01	0.031200	9.64e-01
REACTOME SYNTHESIS OF PC	27	6.97e-01	0.043200	9.64e-01
REACTOME RHOF GTPASE CYCLE	40	6.98e-01	-0.035400	9.64e-01
REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES	7	6.99e-01	-0.084400	9.64e-01
REACTOME O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS	38	7.00e-01	0.036100	9.64e-01
REACTOME INTERLEUKIN 9 SIGNALING	7	7.02e-01	0.083600	9.64e-01
REACTOME HYALURONAN UPTAKE AND DEGRADATION	12	7.02e-01	0.063800	9.64e-01
REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	91	7.02e-01	-0.023200	9.64e-01
REACTOME ERBB2 ACTIVATES PTK6 SIGNALING	13	7.02e-01	-0.061300	9.64e-01
REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	123	7.03e-01	-0.019900	9.65e-01
REACTOME INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS	37	7.03e-01	0.036200	9.65e-01
REACTOME GLUCAGON TYPE LIGAND RECEPTORS	32	7.05e-01	0.038700	9.66e-01
REACTOME ARYL HYDROCARBON RECEPTOR SIGNALLING	6	7.07e-01	0.088700	9.67e-01
REACTOME STAT5 ACTIVATION	7	7.08e-01	0.081800	9.67e-01
REACTOME RESOLUTION OF ABASIC SITES AP SITES	38	7.08e-01	0.035100	9.67e-01
REACTOME TAK1 DEPENDENT IKK AND NF KAPPA B ACTIVATION	41	7.08e-01	0.033700	9.67e-01
REACTOME ER QUALITY CONTROL COMPARTMENT ERQC	21	7.09e-01	-0.047100	9.67e-01
REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH	62	7.09e-01	0.027400	9.67e-01
REACTOME SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER	54	7.12e-01	-0.029100	9.69e-01
REACTOME HYALURONAN BIOSYNTHESIS AND EXPORT	5	7.12e-01	0.095300	9.69e-01
REACTOME HS GAG BIOSYNTHESIS	28	7.13e-01	-0.040100	9.69e-01
REACTOME TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7	12	7.13e-01	-0.061300	9.69e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K	12	7.13e-01	-0.061200	9.69e-01
REACTOME EXTRA NUCLEAR ESTROGEN SIGNALING	74	7.16e-01	0.024500	9.72e-01
REACTOME G ALPHA Z SIGNALLING EVENTS	48	7.18e-01	0.030200	9.72e-01
REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS	6	7.20e-01	-0.084600	9.72e-01
REACTOME G2 M DNA REPLICATION CHECKPOINT	5	7.20e-01	0.092600	9.72e-01
REACTOME FCERI MEDIATED NF KB ACTIVATION	78	7.20e-01	0.023400	9.72e-01
REACTOME UBIQUINOL BIOSYNTHESIS	8	7.20e-01	0.073100	9.72e-01
REACTOME ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA	9	7.20e-01	-0.068900	9.72e-01
REACTOME RESPONSE OF MTB TO PHAGOCYTOSIS	22	7.21e-01	0.044000	9.72e-01
REACTOME ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS	10	7.22e-01	0.064900	9.73e-01
REACTOME OXIDATIVE STRESS INDUCED SENESCENCE	118	7.24e-01	0.018900	9.73e-01
REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE	11	7.24e-01	0.061600	9.73e-01
REACTOME ERBB2 REGULATES CELL MOTILITY	15	7.24e-01	-0.052700	9.73e-01
REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES	21	7.25e-01	0.044400	9.74e-01
REACTOME REGULATION OF TP53 ACTIVITY	156	7.26e-01	0.016300	9.74e-01
REACTOME DISSOLUTION OF FIBRIN CLOT	13	7.27e-01	-0.056000	9.74e-01
REACTOME DEFECTS IN BIOTIN BTN METABOLISM	8	7.27e-01	-0.071300	9.74e-01
REACTOME PI3K EVENTS IN ERBB2 SIGNALING	16	7.28e-01	-0.050300	9.74e-01
REACTOME DAP12 SIGNALING	27	7.29e-01	-0.038600	9.74e-01
REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	16	7.30e-01	-0.049900	9.74e-01
REACTOME RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR	19	7.30e-01	0.045800	9.74e-01
REACTOME INTERFERON ALPHA BETA SIGNALING	70	7.30e-01	0.023800	9.74e-01
REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES	18	7.30e-01	0.046900	9.74e-01
REACTOME AMINO ACID CONJUGATION	9	7.32e-01	0.066000	9.74e-01
REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK	17	7.32e-01	-0.047900	9.74e-01
REACTOME VEGFR2 MEDIATED CELL PROLIFERATION	19	7.33e-01	0.045200	9.74e-01
REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	122	7.33e-01	-0.017900	9.74e-01
REACTOME DISEASES OF METABOLISM	237	7.34e-01	-0.012800	9.74e-01
REACTOME SCAVENGING BY CLASS B RECEPTORS	6	7.34e-01	0.080100	9.74e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX	19	7.35e-01	-0.044800	9.74e-01
REACTOME RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS	5	7.36e-01	0.087200	9.74e-01
REACTOME PHOSPHORYLATION OF THE APC C	20	7.36e-01	-0.043600	9.74e-01
REACTOME KETONE BODY METABOLISM	9	7.36e-01	-0.064900	9.74e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE	8	7.36e-01	0.068700	9.74e-01
REACTOME METABOLISM OF COFACTORS	19	7.39e-01	0.044200	9.74e-01
REACTOME LATE SARS COV 2 INFECTION EVENTS	67	7.40e-01	-0.023500	9.74e-01
REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT	236	7.40e-01	-0.012500	9.74e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1	20	7.42e-01	-0.042600	9.74e-01
REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	15	7.42e-01	-0.049000	9.74e-01
REACTOME INTERLEUKIN 1 PROCESSING	9	7.42e-01	-0.063300	9.74e-01
REACTOME TRNA MODIFICATION IN THE MITOCHONDRION	8	7.43e-01	0.066900	9.74e-01
REACTOME PROCESSING AND ACTIVATION OF SUMO	10	7.45e-01	0.059500	9.74e-01
REACTOME DEFECTIVE CSF2RB CAUSES SMDP5	7	7.45e-01	0.070900	9.74e-01
REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS	55	7.45e-01	-0.025300	9.74e-01
REACTOME INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION	21	7.46e-01	0.040800	9.74e-01
REACTOME INTERLEUKIN 18 SIGNALING	8	7.46e-01	0.066100	9.74e-01
REACTOME REGULATION OF SIGNALING BY NODAL	9	7.47e-01	0.062100	9.74e-01
REACTOME SIGNALING BY HEDGEHOG	148	7.47e-01	-0.015400	9.74e-01
REACTOME PEXOPHAGY	11	7.48e-01	0.055900	9.74e-01
REACTOME CELLULAR SENESCENCE	189	7.50e-01	0.013500	9.74e-01
REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	14	7.50e-01	-0.049200	9.74e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN	13	7.50e-01	0.051000	9.74e-01
REACTOME CREATINE METABOLISM	9	7.50e-01	0.061200	9.74e-01
REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS	5	7.50e-01	-0.082100	9.74e-01
REACTOME NCAM1 INTERACTIONS	41	7.51e-01	0.028700	9.74e-01
REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES	37	7.52e-01	-0.030000	9.74e-01
REACTOME MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS	13	7.53e-01	-0.050400	9.74e-01
REACTOME MET INTERACTS WITH TNS PROTEINS	5	7.53e-01	-0.081100	9.74e-01
REACTOME PREGNENOLONE BIOSYNTHESIS	12	7.54e-01	-0.052200	9.74e-01
REACTOME SIGNALING BY NOTCH1	69	7.56e-01	-0.021700	9.74e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX IN CANCER	8	7.56e-01	0.063500	9.74e-01
REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	45	7.56e-01	-0.026800	9.74e-01
REACTOME LAGGING STRAND SYNTHESIS	19	7.57e-01	0.041000	9.74e-01
REACTOME INDUCTION OF CELL CELL FUSION	12	7.57e-01	0.051500	9.74e-01
REACTOME LDL CLEARANCE	19	7.57e-01	-0.040900	9.74e-01
REACTOME STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES	16	7.58e-01	0.044500	9.74e-01
REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	20	7.58e-01	0.039800	9.74e-01
REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	9	7.59e-01	-0.059000	9.74e-01
REACTOME COBALAMIN CBL METABOLISM	7	7.60e-01	-0.066600	9.74e-01
REACTOME HEMOSTASIS	591	7.60e-01	-0.007350	9.74e-01
REACTOME LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX	5	7.60e-01	-0.078800	9.74e-01
REACTOME CA2 ACTIVATED K CHANNELS	9	7.60e-01	-0.058700	9.74e-01
REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	13	7.61e-01	-0.048800	9.74e-01
REACTOME DISEASES OF MISMATCH REPAIR MMR	5	7.61e-01	0.078600	9.74e-01
REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS	14	7.61e-01	-0.046900	9.75e-01
REACTOME INITIAL TRIGGERING OF COMPLEMENT	21	7.63e-01	0.038000	9.75e-01
REACTOME VXPX CARGO TARGETING TO CILIUM	20	7.63e-01	-0.038900	9.75e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES	15	7.67e-01	-0.044200	9.77e-01
REACTOME TRANSPORT OF FATTY ACIDS	8	7.67e-01	0.060500	9.77e-01
REACTOME KERATAN SULFATE DEGRADATION	13	7.68e-01	-0.047300	9.77e-01
REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION	23	7.68e-01	0.035600	9.77e-01
REACTOME TNFR1 INDUCED PROAPOPTOTIC SIGNALING	23	7.68e-01	0.035500	9.77e-01
REACTOME ADAPTIVE IMMUNE SYSTEM	729	7.68e-01	-0.006410	9.77e-01
REACTOME DEFECTIVE CHST6 CAUSES MCDC1	8	7.69e-01	0.060000	9.77e-01
REACTOME SERINE BIOSYNTHESIS	9	7.69e-01	0.056400	9.77e-01
REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS	15	7.70e-01	0.043700	9.77e-01
REACTOME VITAMIN B2 RIBOFLAVIN METABOLISM	7	7.72e-01	0.063200	9.77e-01
REACTOME SYNTHESIS OF PE	13	7.73e-01	0.046200	9.77e-01
REACTOME NICOTINAMIDE SALVAGING	19	7.73e-01	-0.038200	9.77e-01
REACTOME RND3 GTPASE CYCLE	41	7.73e-01	-0.026000	9.77e-01
REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION	26	7.74e-01	-0.032500	9.77e-01
REACTOME ROBO RECEPTORS BIND AKAP5	9	7.75e-01	-0.055100	9.77e-01
REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	14	7.75e-01	-0.044200	9.77e-01
REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	38	7.75e-01	-0.026800	9.77e-01
REACTOME MET ACTIVATES RAP1 AND RAC1	11	7.76e-01	0.049400	9.78e-01
REACTOME MRNA EDITING	10	7.77e-01	0.051800	9.78e-01
REACTOME VITAMIN B1 THIAMIN METABOLISM	5	7.77e-01	-0.073100	9.78e-01
REACTOME CHL1 INTERACTIONS	9	7.78e-01	-0.054400	9.78e-01
REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS	6	7.79e-01	0.066000	9.79e-01
REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	46	7.81e-01	0.023700	9.79e-01
REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	10	7.81e-01	-0.050700	9.79e-01
REACTOME COLLAGEN CHAIN TRIMERIZATION	42	7.82e-01	-0.024700	9.79e-01
REACTOME HDMS DEMETHYLATE HISTONES	40	7.84e-01	-0.025100	9.79e-01
REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	11	7.85e-01	-0.047500	9.79e-01
REACTOME LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS	19	7.85e-01	0.036100	9.79e-01
REACTOME PREVENTION OF PHAGOSOMAL LYSOSOMAL FUSION	9	7.85e-01	0.052400	9.79e-01
REACTOME RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES	16	7.86e-01	-0.039300	9.79e-01
REACTOME BETA OXIDATION OF BUTANOYL COA TO ACETYL COA	5	7.86e-01	-0.070200	9.79e-01
REACTOME ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY	5	7.86e-01	0.070100	9.79e-01
REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL	13	7.86e-01	-0.043500	9.79e-01
REACTOME SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA	52	7.88e-01	-0.021600	9.79e-01
REACTOME PYROPTOSIS	27	7.88e-01	-0.029900	9.79e-01
REACTOME SIGNALING BY CSF3 G CSF	30	7.89e-01	-0.028300	9.79e-01
REACTOME NETRIN 1 SIGNALING	49	7.89e-01	-0.022100	9.79e-01
REACTOME GLYCOSAMINOGLYCAN METABOLISM	118	7.90e-01	-0.014200	9.79e-01
REACTOME INACTIVATION OF CSF3 G CSF SIGNALING	25	7.90e-01	-0.030800	9.79e-01
REACTOME DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1	9	7.93e-01	0.050600	9.80e-01
REACTOME ESTABLISHMENT OF SISTER CHROMATID COHESION	9	7.93e-01	0.050500	9.80e-01
REACTOME SEROTONIN RECEPTORS	11	7.94e-01	0.045500	9.80e-01
REACTOME SIGNALING BY ERBB2 ECD MUTANTS	16	7.94e-01	0.037700	9.80e-01
REACTOME RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY	14	7.95e-01	-0.040200	9.80e-01
REACTOME DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING	61	7.95e-01	0.019200	9.80e-01
REACTOME TNF SIGNALING	54	7.96e-01	0.020300	9.80e-01
REACTOME SENSING OF DNA DOUBLE STRAND BREAKS	6	7.96e-01	-0.060900	9.80e-01
REACTOME SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS	12	7.96e-01	-0.043000	9.80e-01
REACTOME SHC1 EVENTS IN ERBB2 SIGNALING	22	7.97e-01	-0.031600	9.80e-01
REACTOME IKBA VARIANT LEADS TO EDA ID	6	7.98e-01	-0.060400	9.80e-01
REACTOME CILIUM ASSEMBLY	190	7.98e-01	-0.010800	9.80e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS	11	7.98e-01	0.044500	9.80e-01
REACTOME RECEPTOR MEDIATED MITOPHAGY	10	7.99e-01	0.046600	9.80e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH CDC42	19	7.99e-01	-0.033800	9.80e-01
REACTOME HOMOLOGY DIRECTED REPAIR	132	8.01e-01	0.012700	9.80e-01
REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER	18	8.02e-01	-0.034200	9.80e-01
REACTOME SIGNALING BY NOTCH2	32	8.02e-01	-0.025600	9.80e-01
REACTOME REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION	84	8.02e-01	-0.015800	9.80e-01
REACTOME TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA	36	8.03e-01	0.024100	9.80e-01
REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP	41	8.04e-01	-0.022400	9.80e-01
REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY	25	8.05e-01	-0.028600	9.80e-01
REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	26	8.05e-01	-0.028000	9.80e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS	7	8.06e-01	-0.053700	9.80e-01
REACTOME MINERALOCORTICOID BIOSYNTHESIS	6	8.06e-01	0.057800	9.80e-01
REACTOME TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS	52	8.07e-01	-0.019600	9.80e-01
REACTOME SIGNALING BY LEPTIN	11	8.08e-01	-0.042400	9.80e-01
REACTOME N GLYCAN TRIMMING AND ELONGATION IN THE CIS GOLGI	5	8.08e-01	0.062700	9.80e-01
REACTOME SCAVENGING BY CLASS F RECEPTORS	6	8.09e-01	-0.057000	9.80e-01
REACTOME ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY	10	8.11e-01	0.043700	9.80e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH METHYLATION	19	8.11e-01	0.031700	9.80e-01
REACTOME GPVI MEDIATED ACTIVATION CASCADE	35	8.11e-01	0.023300	9.80e-01
REACTOME WNT MEDIATED ACTIVATION OF DVL	8	8.12e-01	-0.048600	9.80e-01
REACTOME CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2	11	8.13e-01	0.041200	9.80e-01
REACTOME BIOSYNTHESIS OF MARESINS	8	8.13e-01	-0.048300	9.80e-01
REACTOME DEADENYLATION OF MRNA	25	8.15e-01	0.027100	9.80e-01
REACTOME POLO LIKE KINASE MEDIATED EVENTS	16	8.16e-01	0.033700	9.80e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1	25	8.17e-01	-0.026700	9.80e-01
REACTOME LOSS OF FUNCTION OF SMAD2 3 IN CANCER	7	8.17e-01	0.050400	9.80e-01
REACTOME SIGNALLING TO RAS	20	8.18e-01	0.029800	9.80e-01
REACTOME PENTOSE PHOSPHATE PATHWAY	12	8.18e-01	-0.038400	9.80e-01
REACTOME GROWTH HORMONE RECEPTOR SIGNALING	24	8.18e-01	0.027100	9.80e-01
REACTOME SPHINGOLIPID METABOLISM	84	8.18e-01	-0.014500	9.80e-01
REACTOME CYTOCHROME C MEDIATED APOPTOTIC RESPONSE	12	8.18e-01	0.038300	9.80e-01
REACTOME THE ACTIVATION OF ARYLSULFATASES	8	8.19e-01	0.046800	9.80e-01
REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS	6	8.19e-01	-0.053800	9.80e-01
REACTOME DEFECTS IN COBALAMIN B12 METABOLISM	13	8.20e-01	-0.036500	9.80e-01
REACTOME SENSORY PROCESSING OF SOUND	72	8.20e-01	-0.015500	9.80e-01
REACTOME REGULATION OF NF KAPPA B SIGNALING	17	8.20e-01	0.031900	9.80e-01
REACTOME ACTIVATION OF PPARGC1A PGC 1ALPHA BY PHOSPHORYLATION	10	8.20e-01	0.041600	9.80e-01
REACTOME OPIOID SIGNALLING	89	8.23e-01	-0.013700	9.82e-01
REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	24	8.25e-01	0.026100	9.82e-01
REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	18	8.25e-01	0.030100	9.82e-01
REACTOME EPHRIN SIGNALING	17	8.25e-01	0.030900	9.82e-01
REACTOME FATTY ACID METABOLISM	170	8.27e-01	0.009730	9.82e-01
REACTOME SUMOYLATION OF DNA REPLICATION PROTEINS	46	8.27e-01	-0.018600	9.82e-01
REACTOME CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN	45	8.27e-01	-0.018800	9.82e-01
REACTOME DISEASES OF MITOTIC CELL CYCLE	37	8.27e-01	-0.020700	9.82e-01
REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	24	8.28e-01	-0.025700	9.82e-01
REACTOME INTERLEUKIN 12 FAMILY SIGNALING	53	8.28e-01	0.017300	9.82e-01
REACTOME VLDL ASSEMBLY	5	8.29e-01	0.055600	9.82e-01
REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS	188	8.29e-01	-0.009110	9.82e-01
REACTOME RUNX3 REGULATES CDKN1A TRANSCRIPTION	7	8.30e-01	0.047000	9.82e-01
REACTOME IRAK4 DEFICIENCY TLR2 4	17	8.30e-01	0.030100	9.82e-01
REACTOME MITOCHONDRIAL BIOGENESIS	87	8.31e-01	0.013200	9.82e-01
REACTOME G0 AND EARLY G1	27	8.32e-01	-0.023600	9.82e-01
REACTOME ASSEMBLY OF THE HIV VIRION	16	8.34e-01	0.030300	9.84e-01
REACTOME ALPHA DEFENSINS	6	8.34e-01	0.049300	9.84e-01
REACTOME DARPP 32 EVENTS	24	8.35e-01	0.024600	9.84e-01
REACTOME METABOLISM OF VITAMINS AND COFACTORS	185	8.36e-01	-0.008830	9.85e-01
REACTOME SCAVENGING BY CLASS A RECEPTORS	19	8.38e-01	-0.027100	9.86e-01
REACTOME PARASITE INFECTION	57	8.39e-01	-0.015600	9.86e-01
REACTOME G PROTEIN BETA GAMMA SIGNALLING	30	8.39e-01	-0.021500	9.86e-01
REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	7	8.40e-01	-0.043900	9.86e-01
REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES	39	8.42e-01	0.018500	9.86e-01
REACTOME ROLE OF ABL IN ROBO SLIT SIGNALING	8	8.42e-01	-0.040600	9.86e-01
REACTOME GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION	30	8.43e-01	0.020900	9.86e-01
REACTOME DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE	17	8.43e-01	-0.027700	9.86e-01
REACTOME DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS	25	8.45e-01	-0.022600	9.86e-01
REACTOME RELEASE OF HH NP FROM THE SECRETING CELL	8	8.45e-01	-0.039800	9.86e-01
REACTOME PHENYLALANINE METABOLISM	6	8.46e-01	0.045700	9.86e-01
REACTOME ACTIVATION OF AMPK DOWNSTREAM OF NMDARS	28	8.48e-01	0.020900	9.86e-01
REACTOME UNWINDING OF DNA	12	8.49e-01	-0.031800	9.86e-01
REACTOME DEPOLYMERISATION OF THE NUCLEAR LAMINA	14	8.50e-01	0.029200	9.86e-01
REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	14	8.50e-01	-0.029200	9.86e-01
REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	28	8.50e-01	-0.020600	9.86e-01
REACTOME DISEASES OF IMMUNE SYSTEM	29	8.52e-01	-0.020000	9.86e-01
REACTOME CALCITONIN LIKE LIGAND RECEPTORS	10	8.52e-01	0.034000	9.86e-01
REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	32	8.53e-01	0.019000	9.86e-01
REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	45	8.53e-01	-0.016000	9.86e-01
REACTOME GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	34	8.53e-01	0.018400	9.86e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST	14	8.54e-01	0.028400	9.86e-01
REACTOME INTERLEUKIN 7 SIGNALING	31	8.54e-01	0.019100	9.86e-01
REACTOME SIGNALING BY ERBB2	50	8.55e-01	0.014900	9.86e-01
REACTOME ADRENOCEPTORS	9	8.57e-01	-0.034700	9.86e-01
REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	17	8.59e-01	0.024900	9.86e-01
REACTOME DEFECTIVE CHST14 CAUSES EDS MUSCULOCONTRACTURAL TYPE	7	8.59e-01	-0.038800	9.86e-01
REACTOME NUCLEAR EVENTS MEDIATED BY NFE2L2	77	8.61e-01	-0.011600	9.86e-01
REACTOME EPHA MEDIATED GROWTH CONE COLLAPSE	29	8.61e-01	0.018700	9.86e-01
REACTOME BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA	5	8.62e-01	0.045100	9.86e-01
REACTOME SIGNALING BY CSF1 M CSF IN MYELOID CELLS	30	8.62e-01	-0.018400	9.86e-01
REACTOME SUPPRESSION OF PHAGOSOMAL MATURATION	13	8.62e-01	0.027900	9.86e-01
REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	17	8.62e-01	0.024400	9.86e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION	89	8.63e-01	-0.010600	9.86e-01
REACTOME OVARIAN TUMOR DOMAIN PROTEASES	36	8.63e-01	-0.016600	9.86e-01
REACTOME SHC RELATED EVENTS TRIGGERED BY IGF1R	9	8.64e-01	0.033000	9.86e-01
REACTOME BH3 ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI APOPTOTIC BCL 2 MEMBERS	9	8.64e-01	-0.032900	9.86e-01
REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	69	8.65e-01	-0.011800	9.86e-01
REACTOME NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION	193	8.65e-01	-0.007080	9.86e-01
REACTOME G ALPHA I SIGNALLING EVENTS	304	8.66e-01	-0.005650	9.86e-01
REACTOME NEUROFASCIN INTERACTIONS	6	8.66e-01	-0.039900	9.86e-01
REACTOME INOSITOL PHOSPHATE METABOLISM	45	8.66e-01	0.014500	9.86e-01
REACTOME KERATAN SULFATE KERATIN METABOLISM	34	8.66e-01	-0.016700	9.86e-01
REACTOME DOWNREGULATION OF ERBB2 SIGNALING	29	8.67e-01	0.018000	9.86e-01
REACTOME NEDDYLATION	235	8.67e-01	0.006340	9.86e-01
REACTOME CHOLESTEROL BIOSYNTHESIS	25	8.67e-01	-0.019300	9.86e-01
REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF	17	8.68e-01	0.023200	9.86e-01
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION	250	8.70e-01	-0.006010	9.86e-01
REACTOME INACTIVATION OF CDC42 AND RAC1	8	8.70e-01	0.033300	9.86e-01
REACTOME METABOLISM OF INGESTED SEMET SEC MESEC INTO H2SE	7	8.71e-01	0.035400	9.86e-01
REACTOME MET ACTIVATES RAS SIGNALING	11	8.71e-01	0.028200	9.86e-01
REACTOME BIOTIN TRANSPORT AND METABOLISM	10	8.71e-01	-0.029600	9.86e-01
REACTOME SOS MEDIATED SIGNALLING	7	8.72e-01	0.035300	9.86e-01
REACTOME DEFECTIVE B4GALT1 CAUSES B4GALT1 CDG CDG 2D	8	8.72e-01	0.033000	9.86e-01
REACTOME P38MAPK EVENTS	13	8.72e-01	-0.025800	9.86e-01
REACTOME VLDLR INTERNALISATION AND DEGRADATION	16	8.73e-01	-0.023100	9.86e-01
REACTOME STAT3 NUCLEAR EVENTS DOWNSTREAM OF ALK SIGNALING	9	8.74e-01	-0.030600	9.86e-01
REACTOME SYNTHESIS OF LIPOXINS LX	6	8.74e-01	0.037400	9.86e-01
REACTOME SARS COV 2 HOST INTERACTIONS	191	8.74e-01	-0.006650	9.86e-01
REACTOME PTK6 PROMOTES HIF1A STABILIZATION	6	8.76e-01	-0.036900	9.86e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12	22	8.76e-01	0.019300	9.86e-01
REACTOME GPCR LIGAND BINDING	444	8.76e-01	-0.004310	9.86e-01
REACTOME PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR	21	8.77e-01	0.019500	9.86e-01
REACTOME LONG TERM POTENTIATION	22	8.78e-01	0.018900	9.86e-01
REACTOME MET ACTIVATES PI3K AKT SIGNALING	6	8.79e-01	0.035900	9.86e-01
REACTOME REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION	9	8.80e-01	-0.029100	9.86e-01
REACTOME DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS	14	8.80e-01	-0.023300	9.86e-01
REACTOME CLATHRIN MEDIATED ENDOCYTOSIS	139	8.81e-01	-0.007370	9.86e-01
REACTOME N GLYCAN ANTENNAE ELONGATION	15	8.82e-01	-0.022100	9.86e-01
REACTOME SULFUR AMINO ACID METABOLISM	27	8.83e-01	0.016400	9.86e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS	9	8.83e-01	0.028300	9.86e-01
REACTOME TIE2 SIGNALING	18	8.83e-01	0.020000	9.86e-01
REACTOME SURFACTANT METABOLISM	28	8.85e-01	0.015800	9.86e-01
REACTOME COMPLEX I BIOGENESIS	49	8.85e-01	-0.011900	9.86e-01
REACTOME DEFECTIVE LFNG CAUSES SCDO3	5	8.85e-01	0.037300	9.86e-01
REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS	21	8.86e-01	0.018100	9.86e-01
REACTOME SUMO IS TRANSFERRED FROM E1 TO E2 UBE2I UBC9	7	8.86e-01	0.031300	9.86e-01
REACTOME SIGNALING BY MET	78	8.86e-01	-0.009400	9.86e-01
REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	24	8.86e-01	0.016900	9.86e-01
REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	37	8.87e-01	0.013400	9.86e-01
REACTOMEMATURATION OF SARS COV 1 NUCLEOPROTEIN	11	8.88e-01	0.024600	9.86e-01
REACTOME RECYCLING OF EIF2 GDP	7	8.88e-01	0.030700	9.86e-01
REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	20	8.88e-01	-0.018100	9.86e-01
REACTOME INTEGRIN CELL SURFACE INTERACTIONS	83	8.89e-01	0.008890	9.86e-01
REACTOME PRE NOTCH PROCESSING IN GOLGI	18	8.89e-01	-0.018900	9.86e-01
REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	31	8.90e-01	0.014300	9.86e-01
REACTOME TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE	10	8.91e-01	-0.025100	9.86e-01
REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	35	8.91e-01	-0.013400	9.86e-01
REACTOME GLYCOSPHINGOLIPID METABOLISM	39	8.91e-01	-0.012700	9.86e-01
REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	79	8.96e-01	-0.008540	9.91e-01
REACTOME SIGNAL AMPLIFICATION	33	8.96e-01	-0.013200	9.91e-01
REACTOME DUAL INCISION IN GG NER	39	8.97e-01	-0.012000	9.91e-01
REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION	8	8.97e-01	0.026300	9.91e-01
REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	21	8.98e-01	0.016100	9.91e-01
REACTOME ELASTIC FIBRE FORMATION	44	9.00e-01	0.010900	9.91e-01
REACTOME SIGNALING BY PDGF	57	9.01e-01	0.009570	9.91e-01
REACTOME ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA	15	9.01e-01	0.018600	9.91e-01
REACTOME MATURATION OF SARS COV 1 SPIKE PROTEIN	5	9.01e-01	-0.032100	9.91e-01
REACTOME DNA STRAND ELONGATION	31	9.02e-01	0.012800	9.91e-01
REACTOME DSCAM INTERACTIONS	11	9.04e-01	-0.021000	9.91e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION	29	9.05e-01	-0.012800	9.91e-01
REACTOME MOLYBDENUM COFACTOR BIOSYNTHESIS	6	9.05e-01	-0.028100	9.91e-01
REACTOME METABOLISM OF PORPHYRINS	26	9.06e-01	-0.013400	9.91e-01
REACTOME PROSTANOID LIGAND RECEPTORS	9	9.09e-01	-0.022100	9.91e-01
REACTOME GP1B IX V ACTIVATION SIGNALLING	11	9.09e-01	0.019900	9.91e-01
REACTOME KSRP KHSRP BINDS AND DESTABILIZES MRNA	17	9.10e-01	0.015800	9.91e-01
REACTOME ION TRANSPORT BY P TYPE ATPASES	51	9.12e-01	0.008980	9.91e-01
REACTOME RHO GTPASES ACTIVATE IQGAPS	31	9.12e-01	0.011400	9.91e-01
REACTOME ACTIVATION OF BH3 ONLY PROTEINS	30	9.12e-01	-0.011600	9.91e-01
REACTOME MET RECEPTOR ACTIVATION	6	9.15e-01	0.025200	9.91e-01
REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	11	9.15e-01	-0.018600	9.91e-01
REACTOME NEURONAL SYSTEM	388	9.16e-01	-0.003120	9.91e-01
REACTOME ARMS MEDIATED ACTIVATION	7	9.17e-01	0.022900	9.91e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS	12	9.17e-01	0.017400	9.91e-01
REACTOME PYRUVATE METABOLISM	29	9.17e-01	0.011200	9.91e-01
REACTOME SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL	25	9.18e-01	-0.011900	9.91e-01
REACTOME TRIGLYCERIDE METABOLISM	35	9.19e-01	0.009990	9.91e-01
REACTOME ION CHANNEL TRANSPORT	172	9.19e-01	-0.004480	9.91e-01
REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE	9	9.20e-01	0.019400	9.91e-01
REACTOME CONSTITUTIVE SIGNALING BY EGFRVIII	15	9.20e-01	0.015000	9.91e-01
REACTOME FCERI MEDIATED CA 2 MOBILIZATION	30	9.21e-01	0.010500	9.91e-01
REACTOME DEFECTIVE CHST3 CAUSES SEDCJD	7	9.21e-01	0.021600	9.91e-01
REACTOME SMOOTH MUSCLE CONTRACTION	43	9.22e-01	-0.008640	9.91e-01
REACTOME METHYLATION	14	9.23e-01	0.014900	9.91e-01
REACTOME TOLL LIKE RECEPTOR 9 TLR9 CASCADE	100	9.24e-01	-0.005540	9.91e-01
REACTOME INTERLEUKIN RECEPTOR SHC SIGNALING	24	9.24e-01	-0.011300	9.91e-01
REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET	8	9.25e-01	0.019100	9.91e-01
REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE	277	9.26e-01	-0.003230	9.91e-01
REACTOME CRMPS IN SEMA3A SIGNALING	15	9.26e-01	-0.013800	9.91e-01
REACTOME SODIUM COUPLED PHOSPHATE COTRANSPORTERS	5	9.27e-01	0.023800	9.91e-01
REACTOME SUMOYLATION OF SUMOYLATION PROTEINS	35	9.27e-01	0.008980	9.91e-01
REACTOME RND2 GTPASE CYCLE	42	9.28e-01	0.008100	9.91e-01
REACTOME INTERLEUKIN 17 SIGNALING	66	9.28e-01	-0.006420	9.91e-01
REACTOME TRANSCRIPTIONAL REGULATION BY VENTX	41	9.28e-01	-0.008140	9.91e-01
REACTOME BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA	17	9.29e-01	-0.012500	9.91e-01
REACTOME CALCINEURIN ACTIVATES NFAT	9	9.29e-01	0.017100	9.91e-01
REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	17	9.29e-01	0.012400	9.91e-01
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	81	9.30e-01	0.005670	9.91e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM	38	9.31e-01	0.008160	9.91e-01
REACTOME SIGNALING BY ERBB2 IN CANCER	26	9.31e-01	-0.009870	9.91e-01
REACTOME INTERFERON SIGNALING	193	9.31e-01	-0.003620	9.91e-01
REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS	27	9.31e-01	-0.009610	9.91e-01
REACTOME HEDGEHOG OFF STATE	111	9.31e-01	0.004730	9.91e-01
REACTOME ATORVASTATIN ADME	9	9.33e-01	-0.016300	9.91e-01
REACTOME INTEGRATION OF PROVIRUS	9	9.33e-01	-0.016100	9.91e-01
REACTOME MULTIFUNCTIONAL ANION EXCHANGERS	9	9.34e-01	-0.016000	9.91e-01
REACTOME TLR3 MEDIATED TICAM1 DEPENDENT PROGRAMMED CELL DEATH	6	9.34e-01	-0.019600	9.91e-01
REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	19	9.34e-01	0.011000	9.91e-01
REACTOME LTC4 CYSLTR MEDIATED IL4 PRODUCTION	6	9.34e-01	-0.019500	9.91e-01
REACTOME EARLY SARS COV 2 INFECTION EVENTS	34	9.35e-01	0.008110	9.91e-01
REACTOME POTASSIUM CHANNELS	102	9.35e-01	-0.004650	9.91e-01
REACTOME REGULATION OF IFNA IFNB SIGNALING	23	9.35e-01	-0.009770	9.91e-01
REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX	36	9.36e-01	0.007700	9.91e-01
REACTOME ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING	23	9.37e-01	0.009500	9.91e-01
REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION	6	9.40e-01	0.017900	9.91e-01
REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS	17	9.41e-01	-0.010400	9.91e-01
REACTOME RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS	9	9.42e-01	0.014100	9.91e-01
REACTOME DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B	7	9.42e-01	-0.015900	9.91e-01
REACTOME RHO GTPASES ACTIVATE WASPS AND WAVES	34	9.44e-01	-0.006900	9.91e-01
REACTOME DEFECTIVE F9 ACTIVATION	5	9.45e-01	-0.017900	9.91e-01
REACTOME INTERLEUKIN 35 SIGNALLING	12	9.45e-01	0.011500	9.91e-01
REACTOME TACHYKININ RECEPTORS BIND TACHYKININS	5	9.45e-01	0.017800	9.91e-01
REACTOME SUMOYLATION OF UBIQUITINYLATION PROTEINS	39	9.45e-01	0.006380	9.91e-01
REACTOME SNRNP ASSEMBLY	53	9.46e-01	-0.005370	9.91e-01
REACTOME PLATELET HOMEOSTASIS	85	9.46e-01	-0.004240	9.91e-01
REACTOME AMINO ACIDS REGULATE MTORC1	53	9.47e-01	-0.005320	9.91e-01
REACTOME REGULATION OF SIGNALING BY CBL	22	9.47e-01	0.008220	9.91e-01
REACTOME INTERLEUKIN 6 SIGNALING	11	9.47e-01	0.011600	9.91e-01
REACTOME NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS	11	9.47e-01	0.011500	9.91e-01
REACTOME REACTIONS SPECIFIC TO THE COMPLEX N GLYCAN SYNTHESIS PATHWAY	10	9.48e-01	-0.012000	9.91e-01
REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS	312	9.48e-01	0.002140	9.91e-01
REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS	19	9.49e-01	-0.008450	9.91e-01
REACTOME TRANSLESION SYNTHESIS BY POLH	19	9.50e-01	0.008330	9.91e-01
REACTOME EFFECTS OF PIP2 HYDROLYSIS	26	9.50e-01	0.007110	9.91e-01
REACTOME TRAFFICKING OF AMPA RECEPTORS	29	9.50e-01	0.006730	9.91e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING	5	9.51e-01	0.016000	9.91e-01
REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	21	9.51e-01	0.007720	9.91e-01
REACTOME ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS	87	9.51e-01	-0.003780	9.91e-01
REACTOME SYNTHESIS OF PI	5	9.52e-01	0.015600	9.91e-01
REACTOME SIGNALING BY FLT3 FUSION PROTEINS	19	9.52e-01	-0.007990	9.91e-01
REACTOME SARS COV 2 INFECTION	281	9.53e-01	-0.002050	9.91e-01
REACTOME CYTOPROTECTION BY HMOX1	59	9.53e-01	-0.004440	9.91e-01
REACTOME NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	11	9.53e-01	-0.010300	9.91e-01
REACTOME TRANSPORT OF SMALL MOLECULES	697	9.53e-01	-0.001300	9.91e-01
REACTOME CROSS PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS PHAGOSOMES	6	9.54e-01	0.013500	9.91e-01
REACTOME RIBAVIRIN ADME	11	9.54e-01	-0.009940	9.91e-01
REACTOME TRIF MEDIATED PROGRAMMED CELL DEATH	9	9.54e-01	0.011000	9.91e-01
REACTOME THYROXINE BIOSYNTHESIS	10	9.55e-01	0.010200	9.91e-01
REACTOME SLC TRANSPORTER DISORDERS	94	9.56e-01	-0.003280	9.91e-01
REACTOME RUNX2 REGULATES BONE DEVELOPMENT	29	9.56e-01	0.005860	9.91e-01
REACTOME NR1H2 AND NR1H3 MEDIATED SIGNALING	46	9.58e-01	0.004530	9.92e-01
REACTOME OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS	8	9.58e-01	-0.010800	9.92e-01
REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	32	9.59e-01	0.005260	9.92e-01
REACTOME CREATION OF C4 AND C2 ACTIVATORS	14	9.59e-01	-0.007920	9.92e-01
REACTOME PKMTS METHYLATE HISTONE LYSINES	64	9.61e-01	0.003560	9.93e-01
REACTOME MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS	17	9.62e-01	-0.006640	9.94e-01
REACTOME MATURATION OF SARS COV 2 NUCLEOPROTEIN	15	9.63e-01	0.006940	9.94e-01
REACTOME SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION	8	9.64e-01	0.009270	9.94e-01
REACTOME NEGATIVE REGULATION OF MET ACTIVITY	20	9.64e-01	0.005820	9.94e-01
REACTOME AQUAPORIN MEDIATED TRANSPORT	51	9.65e-01	0.003600	9.94e-01
REACTOME DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15	8	9.66e-01	-0.008800	9.94e-01
REACTOME REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA	15	9.67e-01	-0.006090	9.95e-01
REACTOME SPERM MOTILITY AND TAXES	9	9.68e-01	0.007730	9.95e-01
REACTOME INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL	14	9.69e-01	0.006030	9.95e-01
REACTOME PD 1 SIGNALING	21	9.70e-01	0.004750	9.96e-01
REACTOME TOLL LIKE RECEPTOR CASCADES	158	9.71e-01	0.001690	9.96e-01
REACTOME PASSIVE TRANSPORT BY AQUAPORINS	13	9.72e-01	-0.005530	9.96e-01
REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS	33	9.73e-01	-0.003450	9.96e-01
REACTOME SIGNALING BY EGFR IN CANCER	25	9.74e-01	0.003790	9.96e-01
REACTOME DEATH RECEPTOR SIGNALING	143	9.74e-01	-0.001570	9.96e-01
REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB	5	9.74e-01	-0.008330	9.96e-01
REACTOME PHASE 2 PLATEAU PHASE	14	9.76e-01	-0.004610	9.96e-01
REACTOME NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	19	9.77e-01	-0.003880	9.96e-01
REACTOME ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION	28	9.78e-01	0.003060	9.96e-01
REACTOME NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS	22	9.78e-01	-0.003420	9.96e-01
REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS	81	9.79e-01	0.001700	9.96e-01
REACTOME AURKA ACTIVATION BY TPX2	69	9.79e-01	-0.001810	9.96e-01
REACTOME INTRA GOLGI TRAFFIC	43	9.79e-01	0.002270	9.96e-01
REACTOME NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION	20	9.80e-01	-0.003270	9.96e-01
REACTOME SUMO IS PROTEOLYTICALLY PROCESSED	6	9.80e-01	-0.005940	9.96e-01
REACTOME RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION	8	9.81e-01	-0.004830	9.96e-01
REACTOME ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS	41	9.81e-01	0.002110	9.96e-01
REACTOME KERATAN SULFATE BIOSYNTHESIS	28	9.81e-01	-0.002540	9.96e-01
REACTOME INITIATION OF NUCLEAR ENVELOPE NE REFORMATION	18	9.82e-01	-0.003060	9.96e-01
REACTOME NRCAM INTERACTIONS	6	9.83e-01	0.005010	9.96e-01
REACTOME TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS	29	9.84e-01	-0.002200	9.96e-01
REACTOME NRAGE SIGNALS DEATH THROUGH JNK	53	9.84e-01	-0.001570	9.96e-01
REACTOME DEFECTIVE EXT2 CAUSES EXOSTOSES 2	12	9.84e-01	0.003300	9.96e-01
REACTOME MASTL FACILITATES MITOTIC PROGRESSION	10	9.85e-01	-0.003430	9.96e-01
REACTOME SUMO IS CONJUGATED TO E1 UBA2 SAE1	5	9.86e-01	-0.004650	9.96e-01
REACTOME PIWI INTERACTING RNA PIRNA BIOGENESIS	29	9.86e-01	0.001910	9.96e-01
REACTOME FCERI MEDIATED MAPK ACTIVATION	32	9.86e-01	0.001750	9.96e-01
REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV 1 INFECTION	5	9.86e-01	0.004380	9.96e-01
REACTOME DERMATAN SULFATE BIOSYNTHESIS	10	9.88e-01	0.002760	9.96e-01
REACTOME DEX H BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION	7	9.89e-01	-0.003030	9.96e-01
REACTOME SIGNALING BY PDGFR IN DISEASE	20	9.90e-01	0.001660	9.96e-01
REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS	66	9.90e-01	0.000887	9.96e-01
REACTOME SARS COV 2 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS	12	9.90e-01	-0.002010	9.96e-01
REACTOME BASIGIN INTERACTIONS	24	9.91e-01	-0.001400	9.96e-01
REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	89	9.92e-01	-0.000626	9.96e-01
REACTOME SYNTHESIS OF DIPHTHAMIDE EEF2	8	9.93e-01	0.001840	9.96e-01
REACTOME RHOU GTPASE CYCLE	37	9.93e-01	-0.000855	9.96e-01
REACTOME SODIUM CALCIUM EXCHANGERS	11	9.95e-01	-0.001040	9.98e-01
REACTOME SYNAPTIC ADHESION LIKE MOLECULES	19	9.96e-01	0.000680	9.98e-01
REACTOME 2 LTR CIRCLE FORMATION	7	9.96e-01	0.001000	9.98e-01
REACTOME DEFECTIVE CHSY1 CAUSES TPBS	7	9.97e-01	-0.000883	9.98e-01
REACTOME REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS	11	9.98e-01	-0.000438	9.98e-01
REACTOME SARS COV 1 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS	16	9.98e-01	-0.000290	9.98e-01

---

Detailed Gene set reports

REACTOME_OLFACTORY_SIGNALING_PATHWAY

REACTOME_OLFACTORY_SIGNALING_PATHWAY

	628
set	REACTOME_OLFACTORY_SIGNALING_PATHWAY
setSize	348
pANOVA	1.28e-11
s.dist	-0.211
p.adjustANOVA	2.1e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
OR5K3	-9210
OR2M7	-9177
OR6C75	-9158
OR1N1	-9124
OR4E2	-9120
OR13C4	-9115
OR13C2	-9100
OR2A12	-9097
OR2AP1	-9076
OR2T12	-9072
OR2V1	-9052
OR56A3	-9043
OR2T1	-9026
OR51D1	-9011
OR2L5	-8982
OR51T1	-8945
OR10A7	-8940
OR1J1	-8933
OR8B2	-8909
OR6Q1	-8842

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
OR5K3	-9210.0
OR2M7	-9177.0
OR6C75	-9158.0
OR1N1	-9124.0
OR4E2	-9120.0
OR13C4	-9115.0
OR13C2	-9100.0
OR2A12	-9097.0
OR2AP1	-9076.0
OR2T12	-9072.0
OR2V1	-9052.0
OR56A3	-9043.0
OR2T1	-9026.0
OR51D1	-9011.0
OR2L5	-8982.0
OR51T1	-8945.0
OR10A7	-8940.0
OR1J1	-8933.0
OR8B2	-8909.0
OR6Q1	-8842.0
OR6C65	-8832.0
OR6C74	-8810.0
OR6C70	-8799.0
OR10C1	-8795.0
OR2G2	-8776.0
OR1N2	-8757.0
OR2T3	-8747.0
OR52W1	-8735.0
OR4K15	-8733.0
OR5M8	-8723.0
OR52B2	-8714.0
OR2M5	-8705.0
OR5AN1	-8697.0
OR2S2	-8647.0
OR14A16	-8589.0
OR8B12	-8586.0
OR1C1	-8534.0
OR7E24	-8514.0
OR52A5	-8508.0
OR3A2	-8505.0
OR2AG2	-8483.0
OR6B1	-8476.0
OR51V1	-8449.0
OR8I2	-8444.0
OR5A1	-8401.0
OR5C1	-8334.0
OR52I1	-8319.0
OR2V2	-8253.0
OR10J1	-8199.0
OR13D1	-8196.0
OR4D6	-8195.0
OR11H6	-8186.0
OR52N2	-8182.0
OR5B2	-8166.0
OR5M10	-8160.0
OR8B8	-8122.0
OR2B6	-8120.0
OR2L2	-8014.0
OR2W3	-8004.0
OR8B4	-8000.0
OR7G1	-7961.0
OR6K6	-7936.0
OR2K2	-7931.0
OR2D2	-7918.0
OR10A3	-7906.0
OR1L4	-7839.0
OR2B2	-7780.0
OR2AK2	-7688.0
OR5AK2	-7682.0
OR52D1	-7678.0
OR6P1	-7661.0
OR6C6	-7650.0
OR52L1	-7603.0
OR7C1	-7566.0
OR10S1	-7560.0
OR5D13	-7535.0
OR1S2	-7466.0
OR1L8	-7436.0
OR6N2	-7422.0
OR1J2	-7409.0
OR2T4	-7378.0
OR52H1	-7320.0
OR1J4	-7316.0
OR6C68	-7279.0
CNGA4	-7267.0
OR6C1	-7250.0
OR12D2	-7235.0
OR51M1	-7222.0
OR2Z1	-7144.0
OR7D4	-7115.0
OR52I2	-7051.0
OR11L1	-7035.0
OR1M1	-7030.0
OR2A5	-7005.0
OR52E8	-6941.0
OR51B2	-6911.0
OR10A4	-6886.0
OR9G1	-6833.5
OR9G9	-6833.5
OR51F2	-6786.0
OR6C76	-6770.0
OR52R1	-6754.0
OR9A2	-6751.0
OR56A4	-6720.0
OR13C8	-6686.0
OR5W2	-6585.0
OR5V1	-6545.0
OR5F1	-6459.0
OR14C36	-6404.0
OR2AE1	-6388.0
ADCY3	-6384.0
OR2M2	-6357.0
OR5I1	-6344.0
OR6C2	-6342.0
OR1L6	-6327.0
OR51A7	-6249.0
OR2F1	-6212.0
OR2T33	-6179.0
OR5K2	-6134.0
OR56B4	-6093.0
OR9Q1	-6044.0
OR52B6	-6036.0
OR1F1	-6032.0
OR2D3	-6000.0
OR4L1	-5931.0
OR52E2	-5866.0
OR8K1	-5859.0
OR4D5	-5700.0
OR5AS1	-5684.0
OR2C1	-5664.0
OR2A2	-5638.0
OR7G2	-5511.0
OR5D14	-5472.0
OR11H4	-5436.0
OR13A1	-5399.0
OR4D10	-5338.0
OR4K5	-5257.0
OR14J1	-5192.0
OR51B4	-5173.0
OR5A2	-5133.0
OR13G1	-5088.0
OR2M3	-5076.0
OR4K17	-5062.0
OR51E2	-5027.0
OR4D1	-4983.0
OR4B1	-4878.0
OR11G2	-4793.0
OR2G3	-4549.0
OR4A16	-4309.0
OR10A6	-4258.0
OR13C3	-4248.0
OR8G1	-4213.0
OR10Q1	-4123.0
OR6X1	-4102.0
OR5D18	-4002.0
OR8S1	-3945.0
OR5K4	-3879.0
OR4A15	-3760.0
OR2L13	-3744.0
OR56A1	-3684.0
OR5P3	-3622.0
OR52J3	-3620.0
OR6C3	-3486.0
OR4F15	-3479.0
OR3A3	-3369.0
OR2B11	-3119.0
OR2AG1	-3109.0
GNG13	-3059.0
OR5L2	-2977.0
OR1D2	-2940.0
OR4K14	-2895.0
OR6S1	-2856.0
OR5M1	-2840.0
OR10AG1	-2726.0
OR13F1	-2663.0
OR2C3	-2653.0
OR51E1	-2642.0
OR10K1	-2473.0
OR4N2	-2382.0
OR4C3	-2364.0
RTP2	-2208.0
OR52E4	-2186.0
OR8K3	-2169.0
OR8H3	-2030.0
OR51A2	-1900.0
OR5AC2	-1781.0
OR10V1	-1550.0
OR2Y1	-1446.0
OR10J5	-1442.0
OR52N1	-1394.0
OR1G1	-1309.0
OR10G7	-1250.0
OR51S1	-1166.0
OR14I1	-962.0
OR10X1	-786.0
OR5P2	-766.0
OR6F1	-730.0
OR52K1	-659.0
OR4K2	-627.0
REEP1	-534.0
OR5M11	-333.0
OR4D9	-270.0
OR2T8	-266.0
OR4N5	-227.0
OR5T2	-206.0
OR8G5	-148.0
OR10A2	-43.0
OR1S1	13.0
OR5B3	64.0
EBF1	118.0
OR1I1	160.0
OR4S1	311.0
OR5D16	507.0
OR5AP2	607.0
OR4C12	823.0
OR5K1	1465.0
OR10G8	1605.0
OR4D2	1719.0
OR8J3	1780.0
ANO2	1999.0
OR4C15	2057.0
OR5B21	2081.0
OR10H1	2193.0
OR10G9	2196.0
OR1L1	2386.0
OR10H4	2434.0
OR2B3	2442.0
OR8D4	2548.0
OR12D3	2553.0
OR2A14	2699.0
OR2H1	2715.0
OR4C45	2847.0
GNB1	2982.0
OR8U8	3031.0
OR5H1	3279.0
OR9Q2	3301.0
OR8D2	3472.0
OR5B17	3513.0
OR6M1	3531.0
OR8K5	3590.0
OR52K2	3669.0
OR7A17	4100.0
OR6K2	4247.0
OR52M1	4353.0
OR8D1	4548.0
OR2L8	4602.0
OR8U3	4697.0
OR5L1	4717.0
OR7D2	4817.0
OR5M9	4818.0
OR1Q1	4831.0
OR10W1	4849.0
GNAL	4850.0
OR6Y1	4930.0
OR10A5	5132.0
OR5AU1	5164.0
OR2J2	5366.0
OR8J1	5632.0
LHX2	6203.0
OR10H3	6405.0
OR6B3	6443.0
OR10K2	6500.0
OR2L3	6636.0
OR5H2	6648.0
OR2T6	6785.0
OR1E2	6820.0
OR8H1	6865.0
OR1E1	7003.0
OR4M1	7176.0
OR4K1	7336.0
OR8U1	7367.0
OR2W1	7394.0
OR2G6	7417.0
OR51G2	7499.0
OR2F2	7709.0
OR51B5	7770.0
OR9I1	7780.0
OR2AT4	7788.0
OR4A47	7851.0
OR2T27	7936.0
OR6C4	7944.0
OR6T1	8140.0
OR9G4	8294.0
OR1B1	8315.0
OR4F6	8323.0
OR10AD1	8395.0
RTP1	8574.0
OR1L3	8600.0
OR52A1	8603.0
OR7A5	8674.0
OR13C9	8679.0
OR7G3	8709.0
OR6V1	8959.0
OR51G1	9027.0
CNGB1	9097.0
OR51I1	9369.0
OR6N1	9402.0
OR51I2	9555.0
OR7A10	9665.0
OR10Z1	9811.0
OR5M3	9855.0
OR5T3	10031.0
OR10H2	10336.0
OR4K13	10529.0
OR3A1	10587.0
OR11A1	10593.0
OR4C46	10609.0
OR5H15	10630.0
OR10G4	10870.0
OR9K2	10921.0
OR5B12	11108.0
OR6A2	11196.0
LDB1	11419.0
OR56A5	11438.0
OR13J1	11443.0
OR56B1	11478.0
OR51Q1	11525.0
OR8A1	11545.0
OR2T11	11582.0
OR4A5	11591.0
OR10G3	11593.0
OR7C2	11623.0
OR6B2	11626.0
OR10H5	11643.0
OR6K3	11700.0
OR1A2	11705.0
OR5J2	11710.0
OR51L1	11811.0
OR9A4	11852.0
OR5AR1	11865.0
OR51F1	11881.0
OR10J3	11884.0
OR5H6	12008.0
OR2M4	12153.0
OR10T2	12176.0
OR4C16	12202.0
OR4X1	12247.0
OR4C6	12262.0
OR4D11	12321.0
OR10G2	12356.0
OR1A1	12372.0
OR1K1	12385.0
OR51B6	12470.0
OR10P1	12559.0
OR5T1	12606.0
OR2H2	12644.0
OR4X2	12711.5
OR52E6	12747.0

---

REACTOME_SENSORY_PERCEPTION

REACTOME_SENSORY_PERCEPTION

	1581
set	REACTOME_SENSORY_PERCEPTION
setSize	555
pANOVA	2.89e-09
s.dist	-0.147
p.adjustANOVA	2.37e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
OR5K3	-9210
OR2M7	-9177
TAS2R31	-9161
OR6C75	-9158
OR1N1	-9124
OR4E2	-9120
OR13C4	-9115
OR13C2	-9100
OR2A12	-9097
OR2AP1	-9076
OR2T12	-9072
OR2V1	-9052
OR56A3	-9043
OR2T1	-9026
OR51D1	-9011
GNGT1	-8993
OR2L5	-8982
TAS2R14	-8970
OR51T1	-8945
OR10A7	-8940

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
OR5K3	-9210.0
OR2M7	-9177.0
TAS2R31	-9161.0
OR6C75	-9158.0
OR1N1	-9124.0
OR4E2	-9120.0
OR13C4	-9115.0
OR13C2	-9100.0
OR2A12	-9097.0
OR2AP1	-9076.0
OR2T12	-9072.0
OR2V1	-9052.0
OR56A3	-9043.0
OR2T1	-9026.0
OR51D1	-9011.0
GNGT1	-8993.0
OR2L5	-8982.0
TAS2R14	-8970.0
OR51T1	-8945.0
OR10A7	-8940.0
OR1J1	-8933.0
TAS2R7	-8921.0
OR8B2	-8909.0
TAS2R46	-8864.0
OR6Q1	-8842.0
OR6C65	-8832.0
OR6C74	-8810.0
OR6C70	-8799.0
OR10C1	-8795.0
OR2G2	-8776.0
OR1N2	-8757.0
OR2T3	-8747.0
OR52W1	-8735.0
OR4K15	-8733.0
OR5M8	-8723.0
OR52B2	-8714.0
OR2M5	-8705.0
OR5AN1	-8697.0
OR2S2	-8647.0
TAS2R41	-8637.0
OR14A16	-8589.0
OR8B12	-8586.0
OR1C1	-8534.0
GNAT1	-8515.0
OR7E24	-8514.0
GNB3	-8509.0
OR52A5	-8508.0
OR3A2	-8505.0
OR2AG2	-8483.0
OR6B1	-8476.0
OR51V1	-8449.0
OR8I2	-8444.0
TAS2R20	-8416.0
OR5A1	-8401.0
OR5C1	-8334.0
OR52I1	-8319.0
OR2V2	-8253.0
OR10J1	-8199.0
OR13D1	-8196.0
OR4D6	-8195.0
OR11H6	-8186.0
OR52N2	-8182.0
OR5B2	-8166.0
OR5M10	-8160.0
OR8B8	-8122.0
OR2B6	-8120.0
TAS2R39	-8100.0
TAS2R1	-8099.0
RPE65	-8048.0
RBP3	-8036.0
OR2L2	-8014.0
OR2W3	-8004.0
OR8B4	-8000.0
OR7G1	-7961.0
OR6K6	-7936.0
OR2K2	-7931.0
OR2D2	-7918.0
OR10A3	-7906.0
PLCB2	-7890.0
GRXCR1	-7869.0
OR1L4	-7839.0
PNLIP	-7805.0
OR2B2	-7780.0
APOA4	-7771.0
OR2AK2	-7688.0
OR5AK2	-7682.0
OR52D1	-7678.0
OR6P1	-7661.0
OR6C6	-7650.0
OR52L1	-7603.0
OR7C1	-7566.0
OR10S1	-7560.0
OR5D13	-7535.0
SCNN1A	-7508.0
TAS1R3	-7487.0
GSN	-7467.0
OR1S2	-7466.0
OR1L8	-7436.0
OR6N2	-7422.0
OR1J2	-7409.0
OR2T4	-7378.0
OR52H1	-7320.0
OR1J4	-7316.0
OR6C68	-7279.0
CNGA4	-7267.0
OR6C1	-7250.0
OR12D2	-7235.0
OR51M1	-7222.0
SCN3A	-7210.0
OR2Z1	-7144.0
OR7D4	-7115.0
TAS2R50	-7105.0
TAS2R30	-7057.0
OR52I2	-7051.0
OR11L1	-7035.0
OR1M1	-7030.0
OR2A5	-7005.0
OR52E8	-6941.0
SDC4	-6937.0
OR51B2	-6911.0
TAS2R4	-6887.0
OR10A4	-6886.0
OR9G1	-6833.5
OR9G9	-6833.5
OR51F2	-6786.0
RETSAT	-6776.0
OR6C76	-6770.0
OR52R1	-6754.0
OR9A2	-6751.0
OR56A4	-6720.0
OR13C8	-6686.0
FSCN2	-6647.0
EPB41L3	-6615.0
OR5W2	-6585.0
OR5V1	-6545.0
LHFPL5	-6512.0
OR5F1	-6459.0
OR14C36	-6404.0
OR2AE1	-6388.0
ADCY3	-6384.0
OR2M2	-6357.0
OR5I1	-6344.0
OR6C2	-6342.0
OR1L6	-6327.0
RDX	-6288.0
OR51A7	-6249.0
GNB5	-6223.0
OR2F1	-6212.0
OR2T33	-6179.0
OR5K2	-6134.0
TMC1	-6106.0
OR56B4	-6093.0
KCNMB1	-6056.0
OR9Q1	-6044.0
OR52B6	-6036.0
BSN	-6034.0
OR1F1	-6032.0
LRP2	-6010.0
OR2D3	-6000.0
TAS2R38	-5975.0
OR4L1	-5931.0
ESPNL	-5921.0
OR52E2	-5866.0
OR8K1	-5859.0
TWF1	-5757.0
OR4D5	-5700.0
OR5AS1	-5684.0
OR2C1	-5664.0
PCDH15	-5657.0
OR2A2	-5638.0
OR7G2	-5511.0
OR5D14	-5472.0
OR11H4	-5436.0
OR13A1	-5399.0
OR4D10	-5338.0
OR4K5	-5257.0
TAS2R3	-5246.0
OR14J1	-5192.0
OR51B4	-5173.0
OR5A2	-5133.0
OR13G1	-5088.0
OR2M3	-5076.0
OR4K17	-5062.0
OR51E2	-5027.0
OR4D1	-4983.0
PCLO	-4968.0
OR4B1	-4878.0
METAP1	-4870.0
OR11G2	-4793.0
PLS1	-4741.0
OTOF	-4667.0
APOA2	-4663.0
PRKCQ	-4559.0
OR2G3	-4549.0
XIRP2	-4478.0
AKR1C4	-4469.0
RLBP1	-4347.0
OR4A16	-4309.0
OR10A6	-4258.0
OR13C3	-4248.0
OR8G1	-4213.0
TAS2R5	-4204.0
GPC5	-4199.0
OR10Q1	-4123.0
OR6X1	-4102.0
PJVK	-4006.0
OR5D18	-4002.0
HSPG2	-3971.0
OR8S1	-3945.0
SDR9C7	-3895.0
OR5K4	-3879.0
TRPM4	-3865.0
AKR1C1	-3854.0
OR4A15	-3760.0
OR2L13	-3744.0
OR56A1	-3684.0
PDE6A	-3642.0
OR5P3	-3622.0
OR52J3	-3620.0
OTOGL	-3586.0
SCN1B	-3552.0
OR6C3	-3486.0
OR4F15	-3479.0
OR3A3	-3369.0
AKR1C3	-3348.0
DHRS9	-3321.0
RIPOR2	-3311.0
TAS2R40	-3303.0
CALHM3	-3279.0
RBP4	-3275.0
CACNA1D	-3253.0
STX1A	-3161.0
OR2B11	-3119.0
OR2AG1	-3109.0
GNG13	-3059.0
OR5L2	-2977.0
OR1D2	-2940.0
OR4K14	-2895.0
OR6S1	-2856.0
OR5M1	-2840.0
TPRN	-2749.0
OR10AG1	-2726.0
CNGA1	-2682.0
TAS1R2	-2677.0
TAS1R1	-2676.0
OR13F1	-2663.0
OR2C3	-2653.0
OR51E1	-2642.0
SCNN1D	-2496.0
OR10K1	-2473.0
SCN2A	-2392.0
OR4N2	-2382.0
OR4C3	-2364.0
RTP2	-2208.0
OR52E4	-2186.0
OR8K3	-2169.0
OR8H3	-2030.0
GRK1	-1957.0
OR51A2	-1900.0
OR5AC2	-1781.0
GPC6	-1607.0
OR10V1	-1550.0
OR2Y1	-1446.0
OR10J5	-1442.0
OR52N1	-1394.0
GRM1	-1324.0
OR1G1	-1309.0
OR10G7	-1250.0
CAPZA1	-1211.0
OR51S1	-1166.0
GRK7	-1011.0
OR14I1	-962.0
OR10X1	-786.0
OR5P2	-766.0
OR6F1	-730.0
OR52K1	-659.0
SCN2B	-638.0
OR4K2	-627.0
KCNN2	-579.0
REEP1	-534.0
RDH8	-509.0
OTOP1	-498.0
CABP2	-340.0
OR5M11	-333.0
OR4D9	-270.0
OR2T8	-266.0
OR4N5	-227.0
EPS8	-217.0
OR5T2	-206.0
OR8G5	-148.0
OR10A2	-43.0
OR1S1	13.0
OR5B3	64.0
EBF1	118.0
OR1I1	160.0
GUCY2D	265.0
OR4S1	311.0
CHRNA10	334.0
SLC17A8	426.0
MYO3B	466.0
OR5D16	507.0
OR5AP2	607.0
SNAP25	680.0
SPTBN1	767.0
OR4C12	823.0
HSD17B6	870.0
ABCA4	903.0
NAPEPLD	938.0
BCO2	1038.0
PLB1	1169.0
KCNQ4	1193.0
OR5K1	1465.0
MYO15A	1533.0
TRPM5	1566.0
OR10G8	1605.0
CTBP2	1628.0
OR4D2	1719.0
EPS8L2	1741.0
ESPN	1743.0
OR8J3	1780.0
MYO7A	1898.0
TAS2R10	1942.0
ANO2	1999.0
KCNMA1	2001.0
OR4C15	2057.0
OR5B21	2081.0
ITPR3	2140.0
OR10H1	2193.0
CAPZB	2195.0
OR10G9	2196.0
SCNN1B	2210.0
SCN9A	2244.0
AGRN	2259.0
ACTB	2300.0
OR1L1	2386.0
OR10H4	2434.0
OR2B3	2442.0
CALM1	2514.0
OR8D4	2548.0
OR12D3	2553.0
SLC26A5	2593.0
LRP1	2639.0
OR2A14	2699.0
OR2H1	2715.0
AKR1B10	2718.0
SCN4B	2757.0
PRKCA	2793.0
GPC1	2842.0
OR4C45	2847.0
FNTA	2855.0
MYH9	2916.0
GNAT3	2917.0
SPTAN1	2944.0
GNB1	2982.0
CACNA2D2	3030.0
OR8U8	3031.0
CALHM1	3054.0
APOB	3055.0
EZR	3082.0
USH1G	3243.0
OR5H1	3279.0
OR9Q2	3301.0
LRP8	3456.0
OR8D2	3472.0
CDH23	3506.0
OR5B17	3513.0
OR6M1	3531.0
OR8K5	3590.0
OR52K2	3669.0
HSD17B1	3691.0
CYP4V2	3743.0
LDLR	3853.0
RDH5	3912.0
SLC24A1	3966.0
RAB3A	4036.0
OR7A17	4100.0
VAMP2	4176.0
OR6K2	4247.0
OR52M1	4353.0
APOC2	4363.0
CABP1	4424.0
LRRC52	4460.0
TAS2R16	4532.0
OR8D1	4548.0
OR2L8	4602.0
OR8U3	4697.0
OR5L1	4717.0
OR7D2	4817.0
OR5M9	4818.0
OR1Q1	4831.0
OR10W1	4849.0
GNAL	4850.0
SCNN1G	4888.0
CAMKMT	4891.0
RDH12	4904.0
OR6Y1	4930.0
OR10A5	5132.0
OR5AU1	5164.0
RCVRN	5317.0
EPB41L1	5344.0
OTOG	5362.0
OR2J2	5366.0
LRP12	5435.0
GPIHBP1	5521.0
OR8J1	5632.0
RBP2	5797.0
PDE6B	5858.0
BCO1	5863.0
GRK4	5941.0
LPL	6029.0
ACTG1	6055.0
DNAJC5	6096.0
LHX2	6203.0
GUCA1A	6271.0
TTR	6306.0
MYO3A	6358.0
OR10H3	6405.0
OR6B3	6443.0
OR10K2	6500.0
ATP2B2	6527.0
OR2L3	6636.0
OR5H2	6648.0
OR2T6	6785.0
USH1C	6793.0
OR1E2	6820.0
OR8H1	6865.0
CACNB2	6919.0
APOE	6921.0
OR1E1	7003.0
OR4M1	7176.0
TWF2	7268.0
OR4K1	7336.0
OR8U1	7367.0
OR2W1	7394.0
OR2G6	7417.0
OR51G2	7499.0
RDH10	7643.0
OR2F2	7709.0
METAP2	7712.0
OR51B5	7770.0
OR9I1	7780.0
OR2AT4	7788.0
NMT2	7816.0
OR4A47	7851.0
OR2T27	7936.0
OR6C4	7944.0
RGS9	8014.0
RDH16	8053.0
GRXCR2	8072.0
NMT1	8084.0
OR6T1	8140.0
LRP10	8225.0
OR9G4	8294.0
OR1B1	8315.0
MYO1C	8321.0
OR4F6	8323.0
SDC2	8332.0
OR10AD1	8395.0
LRAT	8411.0
CHRNA9	8527.0
RTP1	8574.0
OR1L3	8600.0
OR52A1	8603.0
PDE6G	8607.0
OPN1SW	8616.0
GPC2	8637.0
OR7A5	8674.0
OR13C9	8679.0
DHRS3	8694.0
WHRN	8701.0
OR7G3	8709.0
APOA1	8843.0
SDC1	8871.0
OR6V1	8959.0
OR51G1	9027.0
CAPZA2	9030.0
RGS9BP	9052.0
SAG	9075.0
CIB2	9078.0
APOM	9081.0
CNGB1	9097.0
OR51I1	9369.0
OR6N1	9402.0
RDH11	9481.0
OR51I2	9555.0
OR7A10	9665.0
OR10Z1	9811.0
OR5M3	9855.0
STRA6	9881.0
FNTB	9911.0
CLIC5	10029.0
OR5T3	10031.0
STRC	10112.0
GUCA1C	10165.0
KCNJ2	10227.0
SDC3	10312.0
OR10H2	10336.0
TAS2R13	10349.0
OR4K13	10529.0
OR3A1	10587.0
OR11A1	10593.0
OR4C46	10609.0
OR5H15	10630.0
GRM4	10806.0
TMIE	10845.0
OR10G4	10870.0
OR9K2	10921.0
RHO	10937.0
OR5B12	11108.0
OR6A2	11196.0
TAS2R8	11217.0
LDB1	11419.0
OR56A5	11438.0
OR13J1	11443.0
OR56B1	11478.0
TRIOBP	11491.0
RBP1	11505.0
OR51Q1	11525.0
OR8A1	11545.0
ATP2B1	11570.0
OR2T11	11582.0
OR4A5	11591.0
OR10G3	11593.0
OR7C2	11623.0
OR6B2	11626.0
OR10H5	11643.0
OR6K3	11700.0
OR1A2	11705.0
OR5J2	11710.0
OR51L1	11811.0
OR9A4	11852.0
OR5AR1	11865.0
OR51F1	11881.0
OR10J3	11884.0
TAS2R43	12001.0
OR5H6	12008.0
TMC2	12053.0
OR2M4	12153.0
OR10T2	12176.0
OR4C16	12202.0
OR4X1	12247.0
OR4C6	12262.0
OR4D11	12321.0
OR10G2	12356.0
OR1A1	12372.0
OR1K1	12385.0
GUCA1B	12394.0
APOC3	12399.0
OR51B6	12470.0
OR10P1	12559.0
OR5T1	12606.0
OR2H2	12644.0
CLPS	12708.0
OR4X2	12711.5
OR52E6	12747.0

---

REACTOME_TRANSLATION

REACTOME_TRANSLATION

	1152
set	REACTOME_TRANSLATION
setSize	278
pANOVA	4.71e-07
s.dist	0.176
p.adjustANOVA	0.000258

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MRPL39	12366
RPS3A	12354
RPL35	12299
UBA52	12048
RPL7A	11993
RPS10	11901
MRPL52	11872
FARSB	11846
MRPL37	11686
DAP3	11669
MRPL40	11550
MRPL53	11461
SARS2	11367
MRPS12	11365
EEF1B2	11348
EIF4EBP1	11318
MTRF1L	11016
RPL8	10951
RPS14	10917
GFM2	10888

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MRPL39	12366.0
RPS3A	12354.0
RPL35	12299.0
UBA52	12048.0
RPL7A	11993.0
RPS10	11901.0
MRPL52	11872.0
FARSB	11846.0
MRPL37	11686.0
DAP3	11669.0
MRPL40	11550.0
MRPL53	11461.0
SARS2	11367.0
MRPS12	11365.0
EEF1B2	11348.0
EIF4EBP1	11318.0
MTRF1L	11016.0
RPL8	10951.0
RPS14	10917.0
GFM2	10888.0
RPL13	10880.0
RPS16	10867.0
MRPL50	10769.0
SPCS2	10613.0
RPLP0	10491.0
RPS12	10471.0
EEF1G	10441.0
RPLP1	10423.0
MARS1	10420.0
RPSA	10389.0
RPLP2	10388.0
RPS9	10000.0
RPL27	9921.0
TSFM	9828.0
MRPL32	9779.0
MRPS34	9706.0
RPL19	9586.0
EPRS1	9580.0
EIF2B5	9512.0
RPL10A	9510.0
PPA1	9441.0
RPL28	9439.0
RPS26	9398.0
MRPL12	9379.0
RPL3L	9335.0
RPL15	9318.0
MRPS31	9315.0
RPN1	9251.0
RPS5	9174.0
EEF1E1	9147.0
RPL31	9139.0
EIF3K	9021.0
MRPL58	8978.0
MTFMT	8789.0
PABPC1	8770.0
MRPS11	8726.0
EIF3J	8716.0
RPS23	8529.0
MRPS14	8459.0
SEC61A2	8409.0
FARSA	8370.0
RPS15	8328.0
EIF2S1	8314.0
FAU	8229.0
EIF3D	8186.0
RPL7	8155.0
EIF3B	8149.0
RPS13	8147.0
SRP14	8115.0
EIF3L	8102.0
SEC61B	8083.0
SSR2	7898.0
RPL26L1	7785.0
MRPS21	7745.0
SRP72	7700.0
EIF2B4	7507.0
SSR1	7505.0
GARS1	7353.0
RPS11	7339.0
WARS1	7314.0
MRPL30	7308.0
RPL22L1	7254.0
MRPS23	7191.0
APEH	7156.0
RPL14	7148.0
PTCD3	7147.0
RPS6	7103.0
RPL18	7051.0
RPL32	7038.0
RPL27A	6977.0
SRP54	6943.0
MRPS17	6864.0
RPL3	6848.0
RPS27A	6760.0
MRPL43	6749.0
MRPS5	6744.0
GADD45GIP1	6722.0
PARS2	6654.0
MRPL49	6578.0
LARS2	6546.0
SSR3	6528.0
MRPL9	6466.0
RPL6	6436.0
SPCS1	6407.0
MRPS7	6390.0
MRPL11	6254.0
MRPL46	6191.0
MRPL51	6164.0
MRPS33	6128.0
EIF4A2	6083.0
EARS2	6070.0
MRPL17	6064.0
SRP9	5981.0
MRPL48	5976.0
MRPL14	5927.0
SEC11A	5900.0
MRPL24	5829.0
RPS27L	5802.0
RPL5	5746.0
MRPL44	5705.0
KARS1	5663.0
RPL36	5497.0
RPS18	5479.0
RPL12	5445.0
DARS2	5430.0
CHCHD1	5215.0
MRPL34	5117.0
RPL38	5039.0
SRPRB	5027.0
RPL13A	4893.5
TRMT112	4766.0
WARS2	4746.0
SEC11C	4715.0
EIF4A1	4687.0
MRPS18C	4685.0
RPS8	4682.0
EEF1A2	4676.0
EIF4B	4666.0
EIF3F	4624.0
DARS1	4591.0
RPS15A	4574.0
RPS20	4493.0
RPL35A	4324.0
AARS2	4305.0
AARS1	4264.0
SRPRA	4218.0
ETF1	4159.0
EIF4E	4141.0
PPA2	4090.0
RPS25	3868.0
MRPL36	3605.0
MRPS18A	3520.0
YARS1	3499.0
RPL41	3483.0
MRPL57	3351.0
NARS1	3347.0
RPL18A	3298.0
MRPL33	3272.0
MRPS27	3251.0
RPL23	3249.0
MRPS6	3191.0
RARS1	3123.0
MRPS15	3117.0
EIF5B	3089.0
MRPS2	2863.0
MRPL20	2834.0
EIF4G1	2605.0
TARS2	2573.0
MRPL3	2460.0
MRPL13	2352.0
EEF1A1	2350.0
RARS2	2236.0
MRPL18	2148.0
EIF5	2117.0
RPL17	2047.0
DDOST	1932.0
OXA1L	1926.0
RPL23A	1900.0
AIMP1	1775.0
SPCS3	1769.0
EIF2B1	1582.0
RPS7	1574.0
RPS28	1519.0
MRPL47	1507.0
EIF3M	1389.0
EEF2	1336.0
IARS1	1292.0
ERAL1	1217.0
MRPS18B	1128.0
MRPL1	967.0
RPL10L	887.0
LARS1	883.0
EIF3A	730.0
RPL21	717.0
MRPL54	648.0
HARS2	453.0
MRPS28	275.0
VARS1	179.0
MRPS25	147.0
SEC61A1	95.0
RPL22	19.0
EIF3H	-98.0
RPL36AL	-101.5
RPL24	-132.0
MRPL42	-277.0
RPN2	-299.0
MRPS16	-362.0
SRP19	-393.0
MTIF3	-475.0
MRPL23	-523.0
MRPS22	-667.0
MRPS35	-690.0
RPL30	-725.0
HARS1	-752.0
MRPL15	-868.0
MRRF	-882.0
RPL34	-891.0
MRPS24	-941.0
EIF3E	-1039.0
EIF3G	-1094.0
MARS2	-1133.0
RPS19	-1286.0
RPS27	-1469.0
RPL37A	-1652.0
SRP68	-1710.0
CARS2	-1718.0
MRPL19	-1722.0
EIF3I	-1737.0
TARS1	-1743.0
MRPL27	-1779.0
RPL29	-1880.0
MRPS9	-2056.0
FARS2	-2440.0
RPS2	-2570.0
RPS29	-2664.0
RPL4	-2829.0
RPL37	-3007.0
RPL11	-3010.0
EIF2B2	-3104.0
MRPL21	-3138.0
MRPS10	-3416.0
MRPL10	-3616.0
NARS2	-3727.0
EEF1D	-3891.0
MRPL38	-3896.0
MRPL35	-3935.0
MTIF2	-4076.0
CARS1	-4086.0
RPS21	-4136.0
RPL26	-4270.0
EIF2B3	-4273.0
VARS2	-4401.0
RPS3	-4641.0
YARS2	-4673.0
MRPL55	-4761.0
EIF2S2	-4933.0
RPL9	-5020.0
SEC61G	-5158.0
AURKAIP1	-5298.0
GSPT1	-5383.0
MRPL22	-5395.0
TUFM	-5465.0
IARS2	-5674.0
MRPL41	-5883.0
MRPL16	-5925.0
GFM1	-5983.0
TRAM1	-6067.0
MRPS30	-6456.0
RPL39L	-6470.0
AIMP2	-6842.0
MRPL2	-6873.0
MRPL28	-7069.0
RPS24	-7143.0
N6AMT1	-7401.0
MRPL4	-7582.0
EIF4H	-8086.0
MRPL45	-8170.0
MRPS26	-8328.0

---

REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE

REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE

	271
set	REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE
setSize	105
pANOVA	1.25e-06
s.dist	0.274
p.adjustANOVA	0.000512

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS3A	12354
RPL35	12299
UBA52	12048
RPL7A	11993
RPS10	11901
RPL8	10951
RPS14	10917
RPL13	10880
RPS16	10867
SPCS2	10613
RPLP0	10491
RPS12	10471
RPLP1	10423
RPSA	10389
RPLP2	10388
RPS9	10000
RPL27	9921
RPL19	9586
RPL10A	9510
RPL28	9439

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS3A	12354.0
RPL35	12299.0
UBA52	12048.0
RPL7A	11993.0
RPS10	11901.0
RPL8	10951.0
RPS14	10917.0
RPL13	10880.0
RPS16	10867.0
SPCS2	10613.0
RPLP0	10491.0
RPS12	10471.0
RPLP1	10423.0
RPSA	10389.0
RPLP2	10388.0
RPS9	10000.0
RPL27	9921.0
RPL19	9586.0
RPL10A	9510.0
RPL28	9439.0
RPS26	9398.0
RPL3L	9335.0
RPL15	9318.0
RPN1	9251.0
RPS5	9174.0
RPL31	9139.0
RPS23	8529.0
SEC61A2	8409.0
RPS15	8328.0
FAU	8229.0
RPL7	8155.0
RPS13	8147.0
SRP14	8115.0
SEC61B	8083.0
SSR2	7898.0
RPL26L1	7785.0
SRP72	7700.0
SSR1	7505.0
RPS11	7339.0
RPL22L1	7254.0
RPL14	7148.0
RPS6	7103.0
RPL18	7051.0
RPL32	7038.0
RPL27A	6977.0
SRP54	6943.0
RPL3	6848.0
RPS27A	6760.0
SSR3	6528.0
RPL6	6436.0
SPCS1	6407.0
SRP9	5981.0
SEC11A	5900.0
RPS27L	5802.0
RPL5	5746.0
RPL36	5497.0
RPS18	5479.0
RPL12	5445.0
RPL38	5039.0
SRPRB	5027.0
RPL13A	4893.5
SEC11C	4715.0
RPS8	4682.0
RPS15A	4574.0
RPS20	4493.0
RPL35A	4324.0
SRPRA	4218.0
RPS25	3868.0
RPL41	3483.0
RPL18A	3298.0
RPL23	3249.0
RPL17	2047.0
DDOST	1932.0
RPL23A	1900.0
SPCS3	1769.0
RPS7	1574.0
RPS28	1519.0
RPL10L	887.0
RPL21	717.0
SEC61A1	95.0
RPL22	19.0
RPL36AL	-101.5
RPL24	-132.0
RPN2	-299.0
SRP19	-393.0
RPL30	-725.0
RPL34	-891.0
RPS19	-1286.0
RPS27	-1469.0
RPL37A	-1652.0
SRP68	-1710.0
RPL29	-1880.0
RPS2	-2570.0
RPS29	-2664.0
RPL4	-2829.0
RPL37	-3007.0
RPL11	-3010.0
RPS21	-4136.0
RPL26	-4270.0
RPS3	-4641.0
RPL9	-5020.0
SEC61G	-5158.0
TRAM1	-6067.0
RPL39L	-6470.0
RPS24	-7143.0

---

REACTOME_NONSENSE_MEDIATED_DECAY_NMD

REACTOME_NONSENSE_MEDIATED_DECAY_NMD

	1443
set	REACTOME_NONSENSE_MEDIATED_DECAY_NMD
setSize	107
pANOVA	2.4e-06
s.dist	0.264
p.adjustANOVA	0.00079

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS3A	12354
RPL35	12299
SMG9	12264
UBA52	12048
RPL7A	11993
RPS10	11901
MAGOH	11202
RPL8	10951
RPS14	10917
RPL13	10880
RPS16	10867
SMG5	10675
RPLP0	10491
RPS12	10471
RPLP1	10423
RPSA	10389
RPLP2	10388
RPS9	10000
RPL27	9921
RPL19	9586

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS3A	12354.0
RPL35	12299.0
SMG9	12264.0
UBA52	12048.0
RPL7A	11993.0
RPS10	11901.0
MAGOH	11202.0
RPL8	10951.0
RPS14	10917.0
RPL13	10880.0
RPS16	10867.0
SMG5	10675.0
RPLP0	10491.0
RPS12	10471.0
RPLP1	10423.0
RPSA	10389.0
RPLP2	10388.0
RPS9	10000.0
RPL27	9921.0
RPL19	9586.0
RPL10A	9510.0
RPL28	9439.0
RPS26	9398.0
NCBP1	9341.0
RPL3L	9335.0
RPL15	9318.0
RPS5	9174.0
RPL31	9139.0
PABPC1	8770.0
RPS23	8529.0
RPS15	8328.0
FAU	8229.0
SMG1	8226.0
RPL7	8155.0
RPS13	8147.0
RPL26L1	7785.0
RPS11	7339.0
RPL22L1	7254.0
RPL14	7148.0
RPS6	7103.0
RPL18	7051.0
RPL32	7038.0
PPP2R1A	7026.0
RPL27A	6977.0
CASC3	6900.0
PPP2CA	6858.0
RPL3	6848.0
RPS27A	6760.0
RPL6	6436.0
UPF2	6003.0
RBM8A	5942.0
RPS27L	5802.0
RPL5	5746.0
SMG7	5738.0
RPL36	5497.0
RPS18	5479.0
RPL12	5445.0
NCBP2	5241.0
RPL38	5039.0
RPL13A	4893.5
RPS8	4682.0
RPS15A	4574.0
RPS20	4493.0
RPL35A	4324.0
ETF1	4159.0
RNPS1	3907.0
RPS25	3868.0
UPF3A	3812.0
RPL41	3483.0
RPL18A	3298.0
SMG8	3296.0
RPL23	3249.0
PNRC2	2790.0
EIF4G1	2605.0
RPL17	2047.0
RPL23A	1900.0
RPS7	1574.0
RPS28	1519.0
RPL10L	887.0
RPL21	717.0
RPL22	19.0
RPL36AL	-101.5
RPL24	-132.0
RPL30	-725.0
RPL34	-891.0
DCP1A	-955.0
SMG6	-1125.0
RPS19	-1286.0
RPS27	-1469.0
RPL37A	-1652.0
RPL29	-1880.0
RPS2	-2570.0
RPS29	-2664.0
RPL4	-2829.0
PPP2R2A	-3005.0
RPL37	-3007.0
RPL11	-3010.0
EIF4A3	-3505.0
UPF1	-3627.0
RPS21	-4136.0
RPL26	-4270.0
RPS3	-4641.0
RPL9	-5020.0
GSPT1	-5383.0
MAGOHB	-5870.0
RPL39L	-6470.0
RPS24	-7143.0

---

REACTOME_METABOLISM_OF_RNA

REACTOME_METABOLISM_OF_RNA

	1313
set	REACTOME_METABOLISM_OF_RNA
setSize	675
pANOVA	3.89e-06
s.dist	0.104
p.adjustANOVA	0.00107

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS3A	12354
RPL35	12299
SMG9	12264
SNU13	12241
POM121C	12168
GEMIN5	12076
TRMT5	12066
UBA52	12048
PRPF19	12018
RPP40	12014
RPL7A	11993
GAR1	11910
RPS10	11901
NOL12	11786
DIMT1	11774
PSMD8	11740
HSPB1	11649
SNRNP48	11614
ISG20L2	11613
SNRPB2	11576

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS3A	12354.0
RPL35	12299.0
SMG9	12264.0
SNU13	12241.0
POM121C	12168.0
GEMIN5	12076.0
TRMT5	12066.0
UBA52	12048.0
PRPF19	12018.0
RPP40	12014.0
RPL7A	11993.0
GAR1	11910.0
RPS10	11901.0
NOL12	11786.0
DIMT1	11774.0
PSMD8	11740.0
HSPB1	11649.0
SNRNP48	11614.0
ISG20L2	11613.0
SNRPB2	11576.0
KHSRP	11562.0
PSMB6	11526.0
HNRNPR	11484.0
IMP4	11427.0
LSM7	11421.0
APOBEC1	11409.0
PRPF38A	11351.0
APOBEC3B	11319.0
PSME2	11317.0
RAN	11278.0
SYF2	11218.0
MAGOH	11202.0
LSM10	11182.0
UBL5	11033.0
HNRNPL	11009.0
ADAT3	11002.0
SNRPA1	10986.0
PAIP1	10979.0
DDX6	10967.0
RPL8	10951.0
RPS14	10917.0
POLR2H	10916.0
UTP15	10913.0
DCPS	10911.0
CDK7	10889.0
RPL13	10880.0
RPS16	10867.0
DDX1	10860.0
METTL3	10825.0
PSMD13	10801.0
UTP11	10774.0
POM121	10729.0
SMG5	10675.0
DCP1B	10623.0
GLE1	10614.0
WTAP	10538.0
RPLP0	10491.0
RPS12	10471.0
RPLP1	10423.0
PSMA2	10419.0
RPSA	10389.0
RPLP2	10388.0
NOB1	10363.0
TRIT1	10319.0
RRP36	10274.0
TBL3	10254.0
RRP7A	10211.0
SNRNP70	10146.0
SRSF9	10141.0
NUP155	10125.0
RIOK3	10118.0
FIP1L1	10107.0
ADAT2	10084.0
POLR2J	10004.0
RPS9	10000.0
DDX42	9942.0
RPL27	9921.0
THOC6	9909.0
RPP25	9816.0
SNUPN	9815.0
HNRNPD	9813.0
LSM3	9763.0
THOC5	9719.0
CNOT6L	9691.0
DIS3	9687.0
NXT1	9646.0
FBL	9618.0
RPL19	9586.0
MRM2	9584.0
EPRS1	9580.0
RPL10A	9510.0
DHX16	9504.0
PSMC3	9473.0
RPP21	9472.0
RPL28	9439.0
WDR77	9412.0
RPS26	9398.0
PUS1	9371.0
NCBP1	9341.0
RPL3L	9335.0
PSMC1	9330.0
WDR75	9323.0
RPL15	9318.0
PSMA5	9295.0
SEH1L	9275.0
RPS5	9174.0
RRP9	9162.0
SF3B1	9161.0
RPL31	9139.0
AKT1	9135.0
YWHAB	9072.0
RBM25	8969.0
SRSF3	8924.0
U2AF1L4	8894.0
BOP1	8839.0
SRSF7	8813.0
PABPC1	8770.0
TRMT6	8769.0
LSM2	8751.0
LENG1	8743.0
RBM5	8673.0
EXOSC8	8664.0
CTU1	8659.0
ZFP36L1	8653.0
TYW5	8644.0
CHTOP	8590.0
SET	8567.0
SNRNP200	8538.0
RPS23	8529.0
SEC13	8518.0
UTP18	8506.0
METTL1	8442.0
PRPF4	8358.0
RPS15	8328.0
TRMU	8327.0
DUS2	8309.0
ZNF473	8291.0
NOL11	8270.0
NUP43	8265.0
CPSF2	8252.0
FAU	8229.0
SMG1	8226.0
TSEN34	8224.0
TRMT9B	8207.0
RPL7	8155.0
RPS13	8147.0
CPSF6	8128.0
RBM17	8029.0
CNOT1	8019.0
RRP1	7983.0
CPSF3	7982.0
POP5	7956.0
IK	7920.0
SNRNP25	7918.0
SF3B4	7900.0
TPRKB	7861.0
PSME4	7823.0
RPL26L1	7785.0
PRKCD	7759.0
RBM7	7749.0
EXOSC5	7685.0
XPOT	7556.0
RAE1	7531.0
YWHAZ	7527.0
POLR2L	7368.0
RPS11	7339.0
PSMB10	7323.0
PNN	7322.0
PSMD9	7312.0
THOC7	7273.0
RPL22L1	7254.0
YJU2	7245.0
SNRPD3	7220.0
YBX1	7214.0
CSTF3	7162.0
RPL14	7148.0
POP1	7145.0
RPS6	7103.0
SNRPB	7079.0
RPL18	7051.0
RPL32	7038.0
PPP2R1A	7026.0
PCBP1	7020.0
PHF5A	7012.0
PSMA4	6990.0
RPL27A	6977.0
CNOT8	6947.0
ADAT1	6939.0
PSMB3	6907.0
CASC3	6900.0
SRSF11	6893.0
PELP1	6869.0
SRSF8	6859.0
PPP2CA	6858.0
RPL3	6848.0
UTP3	6813.0
FUS	6777.0
CCNH	6764.0
RPS27A	6760.0
MAPK11	6753.0
LSM4	6737.0
NOP56	6736.0
EFTUD2	6708.0
APOBEC3H	6704.0
IGF2BP3	6692.0
MTERF4	6664.0
C2orf49	6634.0
PPIL1	6623.0
LSM1	6617.0
UTP25	6573.0
DDX5	6558.0
TXNL4A	6545.0
ALYREF	6525.0
UTP4	6520.0
PSME3	6499.0
POLR2A	6488.0
LSM5	6470.0
RPL6	6436.0
SF3A2	6421.0
PPIL4	6369.0
PSMB5	6325.0
IMP3	6314.0
POLR2G	6258.0
WDR18	6251.0
SNRPD2	6248.0
PWP2	6212.0
CTU2	6188.0
ZC3H11A	6182.0
FCF1	6154.0
PDCD11	6150.0
ACIN1	6130.0
TNFSF13	6114.0
EIF4A2	6083.0
UPF2	6003.0
TSEN2	5952.0
RBM8A	5942.0
SRSF1	5919.0
SF3B2	5899.0
RPS27L	5802.0
WBP11	5801.0
TRMT10A	5786.0
SMNDC1	5779.0
OSGEP	5774.0
HSPA8	5756.0
SARNP	5752.0
RPL5	5746.0
SMG7	5738.0
MPHOSPH10	5730.0
GNL3	5649.0
CSTF2T	5609.0
PRPF31	5578.0
TP53RK	5559.0
PSMD11	5530.0
PNO1	5528.0
RPL36	5497.0
RPS18	5479.0
POLR2C	5449.0
RPL12	5445.0
BUD31	5416.0
TGS1	5401.0
USP39	5353.0
RBM22	5314.0
ZMAT2	5284.0
PPIH	5277.0
SRSF12	5243.0
NCBP2	5241.0
NOL6	5235.0
CTNNBL1	5226.0
DDX21	5218.0
MRM3	5182.0
TRMT61B	5080.0
POLR2I	5052.0
RPL38	5039.0
TRNT1	5033.0
DDX20	5017.0
NUP214	4993.0
CNOT7	4990.0
CNOT9	4978.0
CSTF1	4914.0
RPL13A	4893.5
EXOSC7	4885.0
TRA2B	4877.0
CWC15	4873.0
SEM1	4832.0
PSME1	4820.0
TRMT13	4785.0
TRMT112	4766.0
SUGP1	4761.0
MPHOSPH6	4751.0
C9orf78	4736.0
EIF4A1	4687.0
RPS8	4682.0
EIF4B	4666.0
NT5C3B	4665.0
SMU1	4655.0
PSMB8	4635.0
HNRNPU	4600.0
SNRPE	4597.0
RPS15A	4574.0
BYSL	4543.0
PRKRIP1	4506.0
POP4	4502.0
RPS20	4493.0
NAT10	4467.0
DDX41	4370.0
RPL35A	4324.0
PRCC	4181.0
TNKS1BP1	4172.0
ETF1	4159.0
EIF4E	4141.0
SNRNP40	4110.0
HNRNPA1	4099.0
EBNA1BP2	4041.0
EXOSC10	3981.0
NUP133	3960.0
APOBEC3A	3929.0
RNPS1	3907.0
RPP14	3900.0
RPS25	3868.0
SF3A3	3830.0
UPF3A	3812.0
NUP62	3793.0
SRSF4	3792.0
SNRPA	3785.0
SAP18	3724.0
WDR33	3705.0
PPIE	3698.0
UBC	3678.0
PDCD7	3632.0
RNMT	3626.0
XAB2	3589.0
RPL41	3483.0
TSEN54	3476.0
GTF2H5	3475.0
SNIP1	3474.0
SRSF10	3309.0
RPL18A	3298.0
SMG8	3296.0
NUDT21	3265.0
RPL23	3249.0
GCFC2	3244.0
CPSF1	3225.0
NOP14	3171.0
CNOT3	3107.0
DCAF13	3104.0
POLR2K	3074.0
A1CF	3053.0
TSR1	3001.0
TRMT44	2985.0
GTF2H1	2970.0
PUF60	2908.0
TFIP11	2876.0
RCL1	2827.0
PSMA6	2818.0
PRKCA	2793.0
PNRC2	2790.0
URM1	2743.0
NDC1	2732.0
CPSF4	2720.0
ZBTB8OS	2694.0
CHERP	2672.0
RTRAF	2662.0
SNRPN	2645.0
PRPF6	2608.0
EIF4G1	2605.0
CNOT6	2587.0
NOP2	2579.0
IGF2BP1	2508.0
NCL	2450.0
NOC4L	2436.0
POLR2B	2415.0
ERCC3	2407.0
QTRT2	2358.0
POLR2F	2354.0
GEMIN4	2331.0
DDX49	2318.0
NSUN4	2307.0
MTREX	2240.0
HNRNPA2B1	2222.0
NUP37	2220.0
PATL1	2219.0
NSUN6	2146.0
HSPA1A	2130.0
RPL17	2047.0
NSUN2	2043.0
PUS3	1960.0
TYW1	1959.0
PSMD5	1955.0
PSMC2	1937.0
LCMT2	1924.0
PPIG	1903.0
RPL23A	1900.0
PSMB9	1892.0
PSMD14	1828.0
CPSF7	1811.0
SLBP	1798.0
APOBEC3C	1771.0
TEX10	1759.0
GTF2F2	1694.0
DHX8	1661.0
BCAS2	1644.0
PSMD2	1596.0
RPS7	1574.0
RTCB	1540.0
RPS28	1519.0
RIOK2	1501.0
CWC27	1377.0
TRMT61A	1376.0
TYW3	1339.0
BUD23	1312.0
SENP3	1302.0
GTF2H3	1252.0
SRSF6	1204.0
NUP42	1173.0
PCF11	1150.0
PSMB1	1087.0
SNW1	1067.0
BMS1	1021.0
DHX38	1005.0
CNOT2	975.0
RPL10L	887.0
AAAS	854.0
HNRNPM	792.0
NOP58	782.0
TNPO1	778.0
EDC3	755.0
RPL21	717.0
PSMB4	682.0
EXOSC2	613.0
NUP107	598.0
EXOSC6	596.0
ALKBH8	594.0
HNRNPF	593.0
NUP35	590.0
SNRPG	539.0
PPWD1	529.0
SUPT5H	475.0
PSMB7	389.0
PUS7	373.0
SRRM2	287.0
PRMT5	285.0
TSR3	225.0
THOC1	220.0
SRSF5	180.0
FYTTD1	104.0
CDKAL1	87.0
MAPKAPK2	69.0
LTV1	60.0
DDX39A	48.0
RPL22	19.0
ADARB1	-18.0
NUP88	-30.0
AQR	-57.0
RPL36AL	-101.5
NUP93	-114.0
RPL24	-132.0
NUP54	-134.0
CDC5L	-225.0
SRRM1	-250.0
PTBP1	-253.0
POLR2E	-304.0
PSMD1	-344.0
U2SURP	-356.0
PAPOLA	-384.0
THADA	-387.0
GEMIN6	-419.0
ELAVL1	-482.0
NUP210	-490.0
LUC7L3	-520.0
PLRG1	-564.0
PRPF40A	-629.0
PSMB11	-633.0
SKIC2	-684.0
RPL30	-725.0
DHX35	-775.0
RPL34	-891.0
ZCRB1	-905.0
DCP1A	-955.0
ISY1	-965.0
CWC22	-980.0
PSMA3	-1034.0
BUD13	-1090.0
TCERG1	-1105.0
PRPF18	-1124.0
SMG6	-1125.0
NUP160	-1161.0
RPP30	-1175.0
NOL9	-1177.0
NIP7	-1179.0
RPS19	-1286.0
THG1L	-1340.0
WDR36	-1413.0
RPS27	-1469.0
C1D	-1470.0
POLDIP3	-1499.0
MTO1	-1558.0
APOBEC4	-1561.0
RPL37A	-1652.0
GEMIN7	-1677.0
CNOT10	-1683.0
SART1	-1692.0
EMG1	-1708.0
DDX52	-1860.0
CRNKL1	-1878.0
RPL29	-1880.0
WDR4	-1889.0
UTP20	-1896.0
SRSF2	-1921.0
PSMC6	-1967.0
NUP85	-1979.0
PSMD4	-2016.0
DNAJC8	-2070.0
EXOSC4	-2086.0
POLR2D	-2136.0
UTP6	-2145.0
ERI1	-2156.0
SF3B3	-2227.0
PRPF3	-2235.0
DHX15	-2274.0
PSMD3	-2284.0
SNRNP27	-2366.0
NSRP1	-2369.0
MNAT1	-2446.0
HNRNPC	-2463.0
SDE2	-2521.0
PABPN1	-2534.0
PSMD6	-2567.0
RPS2	-2570.0
NUP153	-2599.0
SNRPF	-2601.0
RBM39	-2639.0
ZMAT5	-2649.0
ANP32A	-2650.0
RPS29	-2664.0
HNRNPK	-2704.0
TFB1M	-2723.0
EXOSC3	-2729.0
DHX9	-2739.0
PSMA7	-2741.0
WDR3	-2820.0
RPL4	-2829.0
NXF1	-2862.0
CACTIN	-2898.0
PPIL3	-2933.0
U2AF2	-2945.0
TRMT10C	-2960.0
NUP98	-2974.0
CNOT11	-2986.0
PPP2R2A	-3005.0
RPL37	-3007.0
RPL11	-3010.0
RPP38	-3027.0
SYMPK	-3052.0
PSMF1	-3068.0
NUP50	-3125.0
METTL14	-3169.0
SLU7	-3180.0
HBS1L	-3192.0
CCDC12	-3221.0
RNPC3	-3226.0
DDX46	-3334.0
FAM32A	-3397.0
CLNS1A	-3421.0
CDC40	-3439.0
PRPF8	-3465.0
FAM98B	-3473.0
EIF4A3	-3505.0
GTPBP3	-3513.0
PAN3	-3554.0
NHP2	-3559.0
WDR12	-3598.0
UPF1	-3627.0
RANBP2	-3704.0
PSMB2	-3711.0
TPR	-3725.0
DHX37	-3791.0
EDC4	-3834.0
GTF2F1	-3886.0
PAN2	-3918.0
MRM1	-3985.0
ZNF830	-4034.0
HEATR1	-4071.0
SKIC3	-4099.0
XRN2	-4103.0
RPS21	-4136.0
PSMD12	-4181.0
MAPK14	-4217.0
PSMD7	-4231.0
SF3A1	-4236.0
CSNK1D	-4266.0
RPL26	-4270.0
WDR46	-4280.0
PSMC4	-4337.0
CCAR1	-4381.0
LSM11	-4425.0
DDX39B	-4479.0
RPPH1	-4546.0
RBM42	-4593.0
RPS3	-4641.0
HNRNPA3	-4650.0
CNOT4	-4652.0
NUP205	-4655.0
WBP4	-4695.0
PARN	-4786.0
LSM6	-4804.0
PHAX	-4871.0
UBB	-4879.0
SNRPC	-4910.0
TUT7	-4971.0
RPL9	-5020.0
QTRT1	-5072.0
TSEN15	-5091.0
PES1	-5146.0
PRORP	-5189.0
HNRNPH1	-5197.0
CLP1	-5203.0
XPO1	-5236.0
XRN1	-5286.0
ERCC2	-5326.0
SF1	-5371.0
GSPT1	-5383.0
POP7	-5401.0
CWC25	-5705.0
SNRNP35	-5787.0
MAGOHB	-5870.0
PSMA1	-5911.0
RBM28	-6035.0
PCBP2	-6071.0
DCP2	-6099.0
TUT4	-6169.0
GTF2H4	-6171.0
MFAP1	-6299.0
RIOK1	-6323.0
NUP188	-6377.0
SNRPD1	-6395.0
RPL39L	-6470.0
ADAR	-6479.0
WDR43	-6511.0
SKIC8	-6548.0
EXOSC9	-6550.0
CWF19L2	-6642.0
WDR70	-6643.0
RNGTT	-6664.0
TRMT1	-6668.0
DDX23	-6697.0
GPATCH1	-6817.0
FTSJ3	-6819.0
PPIL2	-6844.0
ZFP36	-6866.0
ELAC2	-6882.0
IGF2BP2	-6942.0
APOBEC2	-6944.0
KRR1	-6962.0
TRDMT1	-6970.0
RPS24	-7143.0
PSMC5	-7244.0
CSNK1E	-7322.0
SMN1	-7547.5
SMN2	-7547.5
SRRT	-7709.0
TRMT11	-7835.0
SF3B5	-7838.0
LSM8	-7883.0
NOP10	-7911.0
TRMT12	-7958.0
EXOSC1	-7962.0
THUMPD1	-7995.0
DDX47	-8032.0
PPP1R8	-8074.0
NUP58	-8164.0
PSMA8	-8172.0
UTP14C	-8273.0
SF3B6	-8600.0
GEMIN2	-8841.0
THOC3	-8903.0

---

REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION

REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION

	151
set	REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION
setSize	87
pANOVA	5.35e-06
s.dist	0.282
p.adjustANOVA	0.00117

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS3A	12354
RPL35	12299
UBA52	12048
RPL7A	11993
RPS10	11901
EEF1B2	11348
RPL8	10951
RPS14	10917
RPL13	10880
RPS16	10867
RPLP0	10491
RPS12	10471
EEF1G	10441
RPLP1	10423
RPSA	10389
RPLP2	10388
RPS9	10000
RPL27	9921
RPL19	9586
RPL10A	9510

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS3A	12354.0
RPL35	12299.0
UBA52	12048.0
RPL7A	11993.0
RPS10	11901.0
EEF1B2	11348.0
RPL8	10951.0
RPS14	10917.0
RPL13	10880.0
RPS16	10867.0
RPLP0	10491.0
RPS12	10471.0
EEF1G	10441.0
RPLP1	10423.0
RPSA	10389.0
RPLP2	10388.0
RPS9	10000.0
RPL27	9921.0
RPL19	9586.0
RPL10A	9510.0
RPL28	9439.0
RPS26	9398.0
RPL3L	9335.0
RPL15	9318.0
RPS5	9174.0
RPL31	9139.0
RPS23	8529.0
RPS15	8328.0
FAU	8229.0
RPL7	8155.0
RPS13	8147.0
RPL26L1	7785.0
RPS11	7339.0
RPL22L1	7254.0
RPL14	7148.0
RPS6	7103.0
RPL18	7051.0
RPL32	7038.0
RPL27A	6977.0
RPL3	6848.0
RPS27A	6760.0
RPL6	6436.0
RPS27L	5802.0
RPL5	5746.0
RPL36	5497.0
RPS18	5479.0
RPL12	5445.0
RPL38	5039.0
RPL13A	4893.5
RPS8	4682.0
EEF1A2	4676.0
RPS15A	4574.0
RPS20	4493.0
RPL35A	4324.0
RPS25	3868.0
RPL41	3483.0
RPL18A	3298.0
RPL23	3249.0
EEF1A1	2350.0
RPL17	2047.0
RPL23A	1900.0
RPS7	1574.0
RPS28	1519.0
EEF2	1336.0
RPL10L	887.0
RPL21	717.0
RPL22	19.0
RPL36AL	-101.5
RPL24	-132.0
RPL30	-725.0
RPL34	-891.0
RPS19	-1286.0
RPS27	-1469.0
RPL37A	-1652.0
RPL29	-1880.0
RPS2	-2570.0
RPS29	-2664.0
RPL4	-2829.0
RPL37	-3007.0
RPL11	-3010.0
EEF1D	-3891.0
RPS21	-4136.0
RPL26	-4270.0
RPS3	-4641.0
RPL9	-5020.0
RPL39L	-6470.0
RPS24	-7143.0

---

REACTOME_EUKARYOTIC_TRANSLATION_INITIATION

REACTOME_EUKARYOTIC_TRANSLATION_INITIATION

	1149
set	REACTOME_EUKARYOTIC_TRANSLATION_INITIATION
setSize	110
pANOVA	5.7e-06
s.dist	0.25
p.adjustANOVA	0.00117

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS3A	12354
RPL35	12299
UBA52	12048
RPL7A	11993
RPS10	11901
EIF4EBP1	11318
RPL8	10951
RPS14	10917
RPL13	10880
RPS16	10867
RPLP0	10491
RPS12	10471
RPLP1	10423
RPSA	10389
RPLP2	10388
RPS9	10000
RPL27	9921
RPL19	9586
EIF2B5	9512
RPL10A	9510

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS3A	12354.0
RPL35	12299.0
UBA52	12048.0
RPL7A	11993.0
RPS10	11901.0
EIF4EBP1	11318.0
RPL8	10951.0
RPS14	10917.0
RPL13	10880.0
RPS16	10867.0
RPLP0	10491.0
RPS12	10471.0
RPLP1	10423.0
RPSA	10389.0
RPLP2	10388.0
RPS9	10000.0
RPL27	9921.0
RPL19	9586.0
EIF2B5	9512.0
RPL10A	9510.0
RPL28	9439.0
RPS26	9398.0
RPL3L	9335.0
RPL15	9318.0
RPS5	9174.0
RPL31	9139.0
EIF3K	9021.0
PABPC1	8770.0
EIF3J	8716.0
RPS23	8529.0
RPS15	8328.0
EIF2S1	8314.0
FAU	8229.0
EIF3D	8186.0
RPL7	8155.0
EIF3B	8149.0
RPS13	8147.0
EIF3L	8102.0
RPL26L1	7785.0
EIF2B4	7507.0
RPS11	7339.0
RPL22L1	7254.0
RPL14	7148.0
RPS6	7103.0
RPL18	7051.0
RPL32	7038.0
RPL27A	6977.0
RPL3	6848.0
RPS27A	6760.0
RPL6	6436.0
EIF4A2	6083.0
RPS27L	5802.0
RPL5	5746.0
RPL36	5497.0
RPS18	5479.0
RPL12	5445.0
RPL38	5039.0
RPL13A	4893.5
EIF4A1	4687.0
RPS8	4682.0
EIF4B	4666.0
EIF3F	4624.0
RPS15A	4574.0
RPS20	4493.0
RPL35A	4324.0
EIF4E	4141.0
RPS25	3868.0
RPL41	3483.0
RPL18A	3298.0
RPL23	3249.0
EIF5B	3089.0
EIF4G1	2605.0
EIF5	2117.0
RPL17	2047.0
RPL23A	1900.0
EIF2B1	1582.0
RPS7	1574.0
RPS28	1519.0
EIF3M	1389.0
RPL10L	887.0
EIF3A	730.0
RPL21	717.0
RPL22	19.0
EIF3H	-98.0
RPL36AL	-101.5
RPL24	-132.0
RPL30	-725.0
RPL34	-891.0
EIF3E	-1039.0
EIF3G	-1094.0
RPS19	-1286.0
RPS27	-1469.0
RPL37A	-1652.0
EIF3I	-1737.0
RPL29	-1880.0
RPS2	-2570.0
RPS29	-2664.0
RPL4	-2829.0
RPL37	-3007.0
RPL11	-3010.0
EIF2B2	-3104.0
RPS21	-4136.0
RPL26	-4270.0
EIF2B3	-4273.0
RPS3	-4641.0
EIF2S2	-4933.0
RPL9	-5020.0
RPL39L	-6470.0
RPS24	-7143.0
EIF4H	-8086.0

---

REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS

REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS

	1364
set	REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS
setSize	161
pANOVA	7.28e-06
s.dist	0.205
p.adjustANOVA	0.00133

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS3A	12354
RPL35	12299
UBA52	12048
RPL7A	11993
RPS10	11901
PSMD8	11740
PSMB6	11526
LDB1	11419
RBX1	11330
PSME2	11317
MAGOH	11202
LHX9	11055
RPL8	10951
RPS14	10917
RPL13	10880
RPS16	10867
PSMD13	10801
HOXA2	10510
RPLP0	10491
RPS12	10471

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS3A	12354.0
RPL35	12299.0
UBA52	12048.0
RPL7A	11993.0
RPS10	11901.0
PSMD8	11740.0
PSMB6	11526.0
LDB1	11419.0
RBX1	11330.0
PSME2	11317.0
MAGOH	11202.0
LHX9	11055.0
RPL8	10951.0
RPS14	10917.0
RPL13	10880.0
RPS16	10867.0
PSMD13	10801.0
HOXA2	10510.0
RPLP0	10491.0
RPS12	10471.0
RPLP1	10423.0
PSMA2	10419.0
RPSA	10389.0
RPLP2	10388.0
RPS9	10000.0
RPL27	9921.0
RPL19	9586.0
RPL10A	9510.0
PSMC3	9473.0
RPL28	9439.0
RPS26	9398.0
NCBP1	9341.0
RPL3L	9335.0
PSMC1	9330.0
RPL15	9318.0
PSMA5	9295.0
RPS5	9174.0
RPL31	9139.0
ISL1	8947.0
PABPC1	8770.0
RPS23	8529.0
RPS15	8328.0
USP33	8280.0
FAU	8229.0
RPL7	8155.0
RPS13	8147.0
PSME4	7823.0
RPL26L1	7785.0
SLIT1	7744.0
CUL2	7630.0
RPS11	7339.0
PSMB10	7323.0
PSMD9	7312.0
RPL22L1	7254.0
RPL14	7148.0
RPS6	7103.0
RPL18	7051.0
RPL32	7038.0
PSMA4	6990.0
RPL27A	6977.0
PSMB3	6907.0
CASC3	6900.0
RPL3	6848.0
RPS27A	6760.0
PSME3	6499.0
RPL6	6436.0
PSMB5	6325.0
LHX2	6203.0
UPF2	6003.0
RBM8A	5942.0
RPS27L	5802.0
RPL5	5746.0
PSMD11	5530.0
RPL36	5497.0
RPS18	5479.0
RPL12	5445.0
NCBP2	5241.0
MSI1	5223.0
RPL38	5039.0
RPL13A	4893.5
SEM1	4832.0
PSME1	4820.0
RPS8	4682.0
PSMB8	4635.0
RPS15A	4574.0
RPS20	4493.0
RPL35A	4324.0
ETF1	4159.0
RNPS1	3907.0
LHX4	3875.0
RPS25	3868.0
UPF3A	3812.0
UBC	3678.0
RPL41	3483.0
RPL18A	3298.0
RPL23	3249.0
PSMA6	2818.0
EIF4G1	2605.0
ROBO3	2575.0
LHX3	2229.0
RPL17	2047.0
DAG1	2041.0
PSMD5	1955.0
PSMC2	1937.0
RPL23A	1900.0
PSMB9	1892.0
PSMD14	1828.0
PSMD2	1596.0
RPS7	1574.0
RPS28	1519.0
PSMB1	1087.0
RPL10L	887.0
RPL21	717.0
PSMB4	682.0
SLIT2	497.0
PSMB7	389.0
RPL22	19.0
RPL36AL	-101.5
RPL24	-132.0
ROBO1	-136.0
PSMD1	-344.0
PSMB11	-633.0
RPL30	-725.0
RPL34	-891.0
PSMA3	-1034.0
RPS19	-1286.0
RPS27	-1469.0
ELOC	-1484.0
RPL37A	-1652.0
RPL29	-1880.0
PSMC6	-1967.0
PSMD4	-2016.0
PSMD3	-2284.0
PSMD6	-2567.0
RPS2	-2570.0
RPS29	-2664.0
PSMA7	-2741.0
RPL4	-2829.0
RPL37	-3007.0
RPL11	-3010.0
PSMF1	-3068.0
EIF4A3	-3505.0
ZSWIM8	-3510.0
PSMB2	-3711.0
ROBO2	-3801.0
RPS21	-4136.0
PSMD12	-4181.0
PSMD7	-4231.0
RPL26	-4270.0
PSMC4	-4337.0
RPS3	-4641.0
UBB	-4879.0
RPL9	-5020.0
GSPT1	-5383.0
MAGOHB	-5870.0
PSMA1	-5911.0
RPL39L	-6470.0
RPS24	-7143.0
PSMC5	-7244.0
PSMA8	-8172.0
ELOB	-8397.0

---

REACTOME_SELENOAMINO_ACID_METABOLISM

REACTOME_SELENOAMINO_ACID_METABOLISM

	484
set	REACTOME_SELENOAMINO_ACID_METABOLISM
setSize	108
pANOVA	3.62e-05
s.dist	0.23
p.adjustANOVA	0.00594

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS3A	12354
RPL35	12299
UBA52	12048
RPL7A	11993
RPS10	11901
GNMT	11535
SEPHS2	11050
RPL8	10951
RPS14	10917
RPL13	10880
RPS16	10867
RPLP0	10491
RPS12	10471
RPLP1	10423
MARS1	10420
RPSA	10389
RPLP2	10388
RPS9	10000
HNMT	9936
RPL27	9921

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS3A	12354.0
RPL35	12299.0
UBA52	12048.0
RPL7A	11993.0
RPS10	11901.0
GNMT	11535.0
SEPHS2	11050.0
RPL8	10951.0
RPS14	10917.0
RPL13	10880.0
RPS16	10867.0
RPLP0	10491.0
RPS12	10471.0
RPLP1	10423.0
MARS1	10420.0
RPSA	10389.0
RPLP2	10388.0
RPS9	10000.0
HNMT	9936.0
RPL27	9921.0
RPL19	9586.0
EPRS1	9580.0
RPL10A	9510.0
RPL28	9439.0
RPS26	9398.0
RPL3L	9335.0
RPL15	9318.0
RPS5	9174.0
EEF1E1	9147.0
RPL31	9139.0
RPS23	8529.0
RPS15	8328.0
FAU	8229.0
RPL7	8155.0
RPS13	8147.0
RPL26L1	7785.0
RPS11	7339.0
RPL22L1	7254.0
RPL14	7148.0
RPS6	7103.0
RPL18	7051.0
RPL32	7038.0
RPL27A	6977.0
GSR	6953.0
RPL3	6848.0
RPS27A	6760.0
RPL6	6436.0
RPS27L	5802.0
RPL5	5746.0
KARS1	5663.0
RPL36	5497.0
RPS18	5479.0
RPL12	5445.0
PAPSS1	5262.0
RPL38	5039.0
NNMT	4911.0
RPL13A	4893.5
RPS8	4682.0
DARS1	4591.0
RPS15A	4574.0
RPS20	4493.0
RPL35A	4324.0
RPS25	3868.0
RPL41	3483.0
RPL18A	3298.0
RPL23	3249.0
RARS1	3123.0
EEFSEC	2669.0
AHCY	2389.0
RPL17	2047.0
RPL23A	1900.0
AIMP1	1775.0
PAPSS2	1608.0
RPS7	1574.0
RPS28	1519.0
IARS1	1292.0
RPL10L	887.0
LARS1	883.0
RPL21	717.0
RPL22	19.0
RPL36AL	-101.5
RPL24	-132.0
RPL30	-725.0
PSTK	-876.0
RPL34	-891.0
RPS19	-1286.0
RPS27	-1469.0
RPL37A	-1652.0
RPL29	-1880.0
SEPSECS	-1998.0
SCLY	-2081.0
RPS2	-2570.0
RPS29	-2664.0
RPL4	-2829.0
RPL37	-3007.0
RPL11	-3010.0
INMT	-3520.0
RPS21	-4136.0
RPL26	-4270.0
CTH	-4527.0
RPS3	-4641.0
TXNRD1	-4823.0
SECISBP2	-5000.0
RPL9	-5020.0
RPL39L	-6470.0
AIMP2	-6842.0
RPS24	-7143.0
MAT1A	-7196.0

---

REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY

REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY

	1486
set	REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY
setSize	94
pANOVA	4.18e-05
s.dist	0.244
p.adjustANOVA	0.00624

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS3A	12354
RPL35	12299
UBA52	12048
RPL7A	11993
RPS10	11901
GCN1	11673
RPL8	10951
RPS14	10917
RPL13	10880
RPS16	10867
RPLP0	10491
RPS12	10471
RPLP1	10423
RPSA	10389
RPLP2	10388
RPS9	10000
RPL27	9921
RPL19	9586
RPL10A	9510
RPL28	9439

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS3A	12354.0
RPL35	12299.0
UBA52	12048.0
RPL7A	11993.0
RPS10	11901.0
GCN1	11673.0
RPL8	10951.0
RPS14	10917.0
RPL13	10880.0
RPS16	10867.0
RPLP0	10491.0
RPS12	10471.0
RPLP1	10423.0
RPSA	10389.0
RPLP2	10388.0
RPS9	10000.0
RPL27	9921.0
RPL19	9586.0
RPL10A	9510.0
RPL28	9439.0
RPS26	9398.0
RPL3L	9335.0
RPL15	9318.0
RPS5	9174.0
RPL31	9139.0
ASNS	8596.0
RPS23	8529.0
RPS15	8328.0
EIF2S1	8314.0
FAU	8229.0
RPL7	8155.0
RPS13	8147.0
RPL26L1	7785.0
IMPACT	7456.0
RPS11	7339.0
RPL22L1	7254.0
RPL14	7148.0
RPS6	7103.0
RPL18	7051.0
RPL32	7038.0
RPL27A	6977.0
RPL3	6848.0
RPS27A	6760.0
RPL6	6436.0
RPS27L	5802.0
RPL5	5746.0
RPL36	5497.0
RPS18	5479.0
RPL12	5445.0
RPL38	5039.0
RPL13A	4893.5
RPS8	4682.0
RPS15A	4574.0
RPS20	4493.0
RPL35A	4324.0
EIF2AK4	4279.0
RPS25	3868.0
TRIB3	3680.0
RPL41	3483.0
RPL18A	3298.0
RPL23	3249.0
RPL17	2047.0
RPL23A	1900.0
RPS7	1574.0
RPS28	1519.0
ATF4	1438.0
RPL10L	887.0
RPL21	717.0
ATF3	25.0
RPL22	19.0
RPL36AL	-101.5
RPL24	-132.0
RPL30	-725.0
RPL34	-891.0
RPS19	-1286.0
RPS27	-1469.0
RPL37A	-1652.0
RPL29	-1880.0
RPS2	-2570.0
RPS29	-2664.0
RPL4	-2829.0
RPL37	-3007.0
RPL11	-3010.0
CEBPG	-3612.0
ATF2	-3745.0
RPS21	-4136.0
RPL26	-4270.0
RPS3	-4641.0
EIF2S2	-4933.0
RPL9	-5020.0
CEBPB	-5278.0
RPL39L	-6470.0
DDIT3	-6649.0
RPS24	-7143.0

---

REACTOME_SIGNALING_BY_ROBO_RECEPTORS

REACTOME_SIGNALING_BY_ROBO_RECEPTORS

	605
set	REACTOME_SIGNALING_BY_ROBO_RECEPTORS
setSize	206
pANOVA	6.1e-05
s.dist	0.162
p.adjustANOVA	0.00834

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS3A	12354
CAP2	12317
RPL35	12299
UBA52	12048
RPL7A	11993
RPS10	11901
PSMD8	11740
PSMB6	11526
LDB1	11419
RBX1	11330
PSME2	11317
MAGOH	11202
LHX9	11055
PFN1	10987
RPL8	10951
RPS14	10917
PRKACG	10893
RPL13	10880
RPS16	10867
PSMD13	10801

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS3A	12354.0
CAP2	12317.0
RPL35	12299.0
UBA52	12048.0
RPL7A	11993.0
RPS10	11901.0
PSMD8	11740.0
PSMB6	11526.0
LDB1	11419.0
RBX1	11330.0
PSME2	11317.0
MAGOH	11202.0
LHX9	11055.0
PFN1	10987.0
RPL8	10951.0
RPS14	10917.0
PRKACG	10893.0
RPL13	10880.0
RPS16	10867.0
PSMD13	10801.0
HOXA2	10510.0
RPLP0	10491.0
RPS12	10471.0
RPLP1	10423.0
PSMA2	10419.0
RPSA	10389.0
RPLP2	10388.0
RPS9	10000.0
RPL27	9921.0
PAK6	9661.0
RPL19	9586.0
RPL10A	9510.0
SRGAP2	9503.0
PSMC3	9473.0
RPL28	9439.0
RPS26	9398.0
NCBP1	9341.0
RPL3L	9335.0
PSMC1	9330.0
RPL15	9318.0
PSMA5	9295.0
RPS5	9174.0
RPL31	9139.0
ISL1	8947.0
PABPC1	8770.0
EVL	8766.0
RPS23	8529.0
ENAH	8495.0
RPS15	8328.0
CXCL12	8287.0
USP33	8280.0
FAU	8229.0
CXCR4	8156.0
RPL7	8155.0
RPS13	8147.0
PSME4	7823.0
RPL26L1	7785.0
SLIT1	7744.0
CUL2	7630.0
RPS11	7339.0
PSMB10	7323.0
PSMD9	7312.0
RPL22L1	7254.0
RPL14	7148.0
RPS6	7103.0
RPL18	7051.0
RPL32	7038.0
PSMA4	6990.0
RPL27A	6977.0
PSMB3	6907.0
CASC3	6900.0
RAC1	6880.0
RPL3	6848.0
RPS27A	6760.0
PSME3	6499.0
RPL6	6436.0
PSMB5	6325.0
LHX2	6203.0
UPF2	6003.0
RHOA	5999.0
RBM8A	5942.0
RPS27L	5802.0
RPL5	5746.0
PSMD11	5530.0
RPL36	5497.0
RPS18	5479.0
RPL12	5445.0
PRKACA	5434.0
NCBP2	5241.0
MSI1	5223.0
RPL38	5039.0
RPL13A	4893.5
SEM1	4832.0
PSME1	4820.0
RPS8	4682.0
PSMB8	4635.0
RPS15A	4574.0
RPS20	4493.0
NTN1	4374.0
NCK1	4325.0
RPL35A	4324.0
ETF1	4159.0
SRGAP1	4003.0
RNPS1	3907.0
LHX4	3875.0
RPS25	3868.0
UPF3A	3812.0
UBC	3678.0
PPP3CB	3538.0
RPL41	3483.0
NRP1	3365.0
RPL18A	3298.0
RPL23	3249.0
PAK2	3046.0
ARHGAP39	2913.0
VASP	2843.0
GPC1	2842.0
PSMA6	2818.0
PRKCA	2793.0
PFN2	2642.0
EIF4G1	2605.0
ROBO3	2575.0
LHX3	2229.0
RPL17	2047.0
DAG1	2041.0
PSMD5	1955.0
PSMC2	1937.0
RPL23A	1900.0
PSMB9	1892.0
CLASP1	1870.0
PSMD14	1828.0
PSMD2	1596.0
RPS7	1574.0
RPS28	1519.0
PRKAR2A	1477.0
PSMB1	1087.0
RPL10L	887.0
RPL21	717.0
PSMB4	682.0
SRC	626.0
SLIT2	497.0
CAP1	486.0
PSMB7	389.0
NELL2	86.0
ABL2	76.0
RPL22	19.0
RPL36AL	-101.5
RPL24	-132.0
ROBO1	-136.0
PSMD1	-344.0
PSMB11	-633.0
RPL30	-725.0
MYO9B	-791.0
RPL34	-891.0
PSMA3	-1034.0
RPS19	-1286.0
SRGAP3	-1445.0
RPS27	-1469.0
ELOC	-1484.0
ABL1	-1504.0
RPL37A	-1652.0
NCK2	-1789.0
SOS2	-1856.0
RPL29	-1880.0
PSMC6	-1967.0
PSMD4	-2016.0
PSMD3	-2284.0
PSMD6	-2567.0
RPS2	-2570.0
RPS29	-2664.0
PSMA7	-2741.0
RPL4	-2829.0
RPL37	-3007.0
RPL11	-3010.0
PSMF1	-3068.0
CLASP2	-3191.0
EIF4A3	-3505.0
ZSWIM8	-3510.0
FLRT3	-3549.0
PSMB2	-3711.0
ROBO2	-3801.0
RPS21	-4136.0
PSMD12	-4181.0
PSMD7	-4231.0
RPL26	-4270.0
DCC	-4278.0
PSMC4	-4337.0
SLIT3	-4394.0
RPS3	-4641.0
SOS1	-4686.0
UBB	-4879.0
RPL9	-5020.0
PAK1	-5045.0
CDC42	-5289.0
GSPT1	-5383.0
PAK5	-5826.0
MAGOHB	-5870.0
PSMA1	-5911.0
AKAP5	-6009.0
RPL39L	-6470.0
PRKACB	-6617.0
RPS24	-7143.0
PSMC5	-7244.0
PAK4	-8079.0
PSMA8	-8172.0
ELOB	-8397.0

---

REACTOME_SENSORY_PERCEPTION_OF_TASTE

REACTOME_SENSORY_PERCEPTION_OF_TASTE

	1586
set	REACTOME_SENSORY_PERCEPTION_OF_TASTE
setSize	47
pANOVA	8.98e-05
s.dist	-0.33
p.adjustANOVA	0.0113

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TAS2R31	-9161
TAS2R14	-8970
TAS2R7	-8921
TAS2R46	-8864
TAS2R41	-8637
GNB3	-8509
TAS2R20	-8416
TAS2R39	-8100
TAS2R1	-8099
PLCB2	-7890
SCNN1A	-7508
TAS1R3	-7487
SCN3A	-7210
TAS2R50	-7105
TAS2R30	-7057
TAS2R4	-6887
TAS2R38	-5975
TAS2R3	-5246
TAS2R5	-4204
TRPM4	-3865

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TAS2R31	-9161
TAS2R14	-8970
TAS2R7	-8921
TAS2R46	-8864
TAS2R41	-8637
GNB3	-8509
TAS2R20	-8416
TAS2R39	-8100
TAS2R1	-8099
PLCB2	-7890
SCNN1A	-7508
TAS1R3	-7487
SCN3A	-7210
TAS2R50	-7105
TAS2R30	-7057
TAS2R4	-6887
TAS2R38	-5975
TAS2R3	-5246
TAS2R5	-4204
TRPM4	-3865
SCN1B	-3552
TAS2R40	-3303
CALHM3	-3279
GNG13	-3059
TAS1R2	-2677
TAS1R1	-2676
SCNN1D	-2496
SCN2A	-2392
GRM1	-1324
SCN2B	-638
OTOP1	-498
TRPM5	1566
TAS2R10	1942
ITPR3	2140
SCNN1B	2210
SCN9A	2244
SCN4B	2757
GNAT3	2917
GNB1	2982
CALHM1	3054
TAS2R16	4532
SCNN1G	4888
KCNJ2	10227
TAS2R13	10349
GRM4	10806
TAS2R8	11217
TAS2R43	12001

---

REACTOME_RRNA_PROCESSING

REACTOME_RRNA_PROCESSING

	1148
set	REACTOME_RRNA_PROCESSING
setSize	192
pANOVA	0.000114
s.dist	0.161
p.adjustANOVA	0.0134

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS3A	12354
RPL35	12299
SNU13	12241
UBA52	12048
RPP40	12014
RPL7A	11993
GAR1	11910
RPS10	11901
NOL12	11786
DIMT1	11774
ISG20L2	11613
IMP4	11427
RPL8	10951
RPS14	10917
UTP15	10913
RPL13	10880
RPS16	10867
UTP11	10774
RPLP0	10491
RPS12	10471

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS3A	12354.0
RPL35	12299.0
SNU13	12241.0
UBA52	12048.0
RPP40	12014.0
RPL7A	11993.0
GAR1	11910.0
RPS10	11901.0
NOL12	11786.0
DIMT1	11774.0
ISG20L2	11613.0
IMP4	11427.0
RPL8	10951.0
RPS14	10917.0
UTP15	10913.0
RPL13	10880.0
RPS16	10867.0
UTP11	10774.0
RPLP0	10491.0
RPS12	10471.0
RPLP1	10423.0
RPSA	10389.0
RPLP2	10388.0
NOB1	10363.0
RRP36	10274.0
TBL3	10254.0
RRP7A	10211.0
RIOK3	10118.0
RPS9	10000.0
RPL27	9921.0
RPP25	9816.0
DIS3	9687.0
FBL	9618.0
RPL19	9586.0
MRM2	9584.0
RPL10A	9510.0
RPP21	9472.0
RPL28	9439.0
RPS26	9398.0
RPL3L	9335.0
WDR75	9323.0
RPL15	9318.0
RPS5	9174.0
RRP9	9162.0
RPL31	9139.0
BOP1	8839.0
EXOSC8	8664.0
RPS23	8529.0
UTP18	8506.0
RPS15	8328.0
NOL11	8270.0
FAU	8229.0
RPL7	8155.0
RPS13	8147.0
RRP1	7983.0
RPL26L1	7785.0
EXOSC5	7685.0
RPS11	7339.0
RPL22L1	7254.0
RPL14	7148.0
RPS6	7103.0
RPL18	7051.0
RPL32	7038.0
RPL27A	6977.0
PELP1	6869.0
RPL3	6848.0
UTP3	6813.0
RPS27A	6760.0
NOP56	6736.0
MTERF4	6664.0
UTP25	6573.0
UTP4	6520.0
RPL6	6436.0
IMP3	6314.0
WDR18	6251.0
PWP2	6212.0
FCF1	6154.0
PDCD11	6150.0
RPS27L	5802.0
RPL5	5746.0
MPHOSPH10	5730.0
GNL3	5649.0
PNO1	5528.0
RPL36	5497.0
RPS18	5479.0
RPL12	5445.0
NOL6	5235.0
DDX21	5218.0
MRM3	5182.0
RPL38	5039.0
RPL13A	4893.5
EXOSC7	4885.0
TRMT112	4766.0
MPHOSPH6	4751.0
RPS8	4682.0
RPS15A	4574.0
BYSL	4543.0
RPS20	4493.0
NAT10	4467.0
RPL35A	4324.0
EBNA1BP2	4041.0
EXOSC10	3981.0
RPP14	3900.0
RPS25	3868.0
RPL41	3483.0
RPL18A	3298.0
RPL23	3249.0
NOP14	3171.0
DCAF13	3104.0
TSR1	3001.0
RCL1	2827.0
NOP2	2579.0
NCL	2450.0
NOC4L	2436.0
DDX49	2318.0
NSUN4	2307.0
MTREX	2240.0
RPL17	2047.0
RPL23A	1900.0
TEX10	1759.0
RPS7	1574.0
RPS28	1519.0
RIOK2	1501.0
BUD23	1312.0
SENP3	1302.0
BMS1	1021.0
RPL10L	887.0
NOP58	782.0
RPL21	717.0
EXOSC2	613.0
EXOSC6	596.0
TSR3	225.0
LTV1	60.0
RPL22	19.0
RPL36AL	-101.5
RPL24	-132.0
RPL30	-725.0
RPL34	-891.0
RPP30	-1175.0
NOL9	-1177.0
NIP7	-1179.0
RPS19	-1286.0
WDR36	-1413.0
RPS27	-1469.0
C1D	-1470.0
RPL37A	-1652.0
EMG1	-1708.0
DDX52	-1860.0
RPL29	-1880.0
UTP20	-1896.0
EXOSC4	-2086.0
UTP6	-2145.0
ERI1	-2156.0
RPS2	-2570.0
RPS29	-2664.0
TFB1M	-2723.0
EXOSC3	-2729.0
WDR3	-2820.0
RPL4	-2829.0
TRMT10C	-2960.0
RPL37	-3007.0
RPL11	-3010.0
RPP38	-3027.0
NHP2	-3559.0
WDR12	-3598.0
DHX37	-3791.0
MRM1	-3985.0
HEATR1	-4071.0
XRN2	-4103.0
RPS21	-4136.0
CSNK1D	-4266.0
RPL26	-4270.0
WDR46	-4280.0
RPS3	-4641.0
RPL9	-5020.0
PES1	-5146.0
PRORP	-5189.0
RBM28	-6035.0
RIOK1	-6323.0
RPL39L	-6470.0
WDR43	-6511.0
EXOSC9	-6550.0
FTSJ3	-6819.0
ELAC2	-6882.0
KRR1	-6962.0
RPS24	-7143.0
CSNK1E	-7322.0
NOP10	-7911.0
EXOSC1	-7962.0
THUMPD1	-7995.0
DDX47	-8032.0
UTP14C	-8273.0

---

REACTOME_SIGNALING_BY_FGFR

REACTOME_SIGNALING_BY_FGFR

	306
set	REACTOME_SIGNALING_BY_FGFR
setSize	85
pANOVA	0.000164
s.dist	0.236
p.adjustANOVA	0.018

Top enriched genes

Top 20 genes

GeneID	Gene Rank
UBA52	12048
FGF20	11659
PPP2CB	11602
ESRP2	11503
FLRT1	11382
SPRED1	11131
POLR2H	10916
FGF5	10861
HRAS	10478
FGFBP1	10449
MAPK3	10376
FGF22	10147
POLR2J	10004
FGFBP2	9882
FGF17	9443
MAPK1	9390
NCBP1	9341
FGF4	8965
FGF9	8830
FRS3	8566

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
UBA52	12048
FGF20	11659
PPP2CB	11602
ESRP2	11503
FLRT1	11382
SPRED1	11131
POLR2H	10916
FGF5	10861
HRAS	10478
FGFBP1	10449
MAPK3	10376
FGF22	10147
POLR2J	10004
FGFBP2	9882
FGF17	9443
MAPK1	9390
NCBP1	9341
FGF4	8965
FGF9	8830
FRS3	8566
PLCG1	8474
FGF19	8372
FGF8	8081
FGF3	7841
FGFR4	7821
KL	7480
FGFR2	7428
FGFR3	7405
POLR2L	7368
FGF6	7242
PPP2R1A	7026
PPP2CA	6858
FGFBP3	6812
RPS27A	6760
POLR2A	6488
FGF1	6404
PTPN11	6327
POLR2G	6258
TIAL1	6137
POLR2C	5449
KLB	5388
FGF23	5385
NCBP2	5241
FGF10	5079
POLR2I	5052
SPRY2	4430
GRB2	4417
BRAF	4204
SHC1	4171
HNRNPA1	4099
PIK3CA	3688
UBC	3678
POLR2K	3074
FGFRL1	2806
POLR2B	2415
POLR2F	2354
GTF2F2	1694
FRS2	1660
SPRED2	1315
RBFOX2	1154
FGFR1	835
HNRNPM	792
ESRP1	658
SRC	626
HNRNPF	593
PIK3R1	517
FLRT2	110
GAB1	-61
PTBP1	-253
POLR2E	-304
NRAS	-916
TIA1	-1393
CBL	-1592
POLR2D	-2136
KRAS	-2609
FGF2	-2778
FLRT3	-3549
MKNK1	-3811
GTF2F1	-3886
GALNT3	-4050
SOS1	-4686
UBB	-4879
HNRNPH1	-5197
FGF18	-6573
FGF7	-6850

---

REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

	1161
set	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION
setSize	1336
pANOVA	0.000204
s.dist	0.0605
p.adjustANOVA	0.021

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ZNF597	12727
ZNF736	12691
CGB5	12580
CCN2	12491
RETN	12464
H2BC26	12438
ZNF431	12412
UCMA	12364
CGB8	12308
FOXO6	12240
ZNF333	12213
CCNT1	12196
REST	12191
TNFRSF18	12180
ZNF770	12166
ZNF470	12150
ZNF432	12144
ZNF790	12138
ZNF676	12120
HEY1	12116

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ZNF597	12727.0
ZNF736	12691.0
CGB5	12580.0
CCN2	12491.0
RETN	12464.0
H2BC26	12438.0
ZNF431	12412.0
UCMA	12364.0
CGB8	12308.0
FOXO6	12240.0
ZNF333	12213.0
CCNT1	12196.0
REST	12191.0
TNFRSF18	12180.0
ZNF770	12166.0
ZNF470	12150.0
ZNF432	12144.0
ZNF790	12138.0
ZNF676	12120.0
HEY1	12116.0
H3C2	12075.0
ZNF19	12059.0
UBA52	12048.0
MIR24-1	12004.0
RNU11	12003.0
COX6B1	11987.0
ANAPC1	11979.0
ZNF441	11957.0
NPPA	11947.0
CDKN2B	11922.0
ZNF544	11862.0
H2AC18	11842.5
H2AC19	11842.5
PCGF2	11783.0
TMEM219	11767.0
PSMD8	11740.0
SMARCE1	11735.0
ZNF354C	11709.0
ZNF552	11657.0
ZNF442	11603.0
PPP2CB	11602.0
KLF4	11595.0
USP2	11592.0
PSMB6	11526.0
TAL1	11501.0
INTS5	11498.0
PCK1	11497.0
LDB1	11419.0
RORC	11405.0
TNFRSF10D	11392.0
SOCS4	11380.0
SSRP1	11363.0
MEAF6	11346.0
RBX1	11330.0
PSME2	11317.0
ZNF585A	11283.0
ZNF440	11249.0
TRIM28	11241.0
CDK5R1	11233.0
VDR	11227.0
MEN1	11203.0
MAGOH	11202.0
ZNF214	11199.0
SOX9	11195.0
LSM10	11182.0
ZNF205	11173.0
KMT5A	11101.0
TFAP2B	11085.0
ZNF530	11068.0
ZNF621	11027.0
ZNF263	10998.0
ESR2	10997.0
SIRT3	10955.0
PMS2	10946.0
H4C12	10931.0
POLR2H	10916.0
DLX5	10904.0
CDK7	10889.0
HDAC11	10883.0
RRAGD	10877.0
SST	10875.0
ZIK1	10866.0
TAF6	10850.0
ZNF304	10848.0
LGALS3	10830.0
PSMD13	10801.0
NDUFA4	10777.0
DLL1	10762.0
PRDM1	10747.0
RABGGTB	10713.0
ZNF740	10705.0
ZNF79	10703.0
ZNF418	10688.0
ZNF620	10662.0
ZNF222	10657.0
TAF9	10628.0
ZNF701	10606.0
ZNF415	10598.0
JUN	10584.0
ZNF75A	10565.0
ITGA2B	10549.0
ZNF625	10531.0
CCNE2	10522.0
NR2C2	10514.0
OPRK1	10504.0
ZNF667	10500.0
LEO1	10496.0
TWIST1	10486.0
CBFB	10474.0
ZNF729	10462.0
PSMA2	10419.0
ZNF141	10415.0
FBXO32	10397.0
AGO4	10384.0
ZNF197	10383.0
MAPK3	10376.0
ZNF561	10364.0
ZNF484	10326.0
ING2	10324.0
POMC	10267.0
NR2E1	10251.0
CITED2	10249.0
H4C8	10222.0
AGO1	10202.0
H4C9	10176.0
CSNK2B	10153.0
SRSF9	10141.0
ZFP28	10124.0
CDKN1A	10113.0
FIP1L1	10107.0
PRKAB1	10086.0
SUMO1	10073.0
TCF7	10062.0
ZNF416	10061.0
AIFM2	10060.0
COX14	10054.0
RFC5	10050.0
ZNF468	10047.0
RARG	10022.0
ZNF703	10014.0
POLR2J	10004.0
ELF1	9987.0
ZNF417	9979.0
COX4I1	9976.0
H2BC8	9970.0
ZNF426	9967.0
THOC6	9909.0
ZNF101	9897.0
PRKAG1	9891.0
RAD51	9885.0
TACO1	9873.0
ZNF223	9867.0
SMAD7	9862.0
CDK4	9809.0
ZNF496	9803.0
ANAPC10	9802.0
CAMK2A	9796.0
ZNF189	9791.0
ZNF77	9748.0
ZNF772	9732.0
THOC5	9719.0
ZNF180	9702.0
CLDN5	9699.0
CNOT6L	9691.0
RAD17	9658.0
ZNF155	9653.0
H3C12	9636.0
CCNA1	9633.0
POU4F2	9625.0
ZNF500	9623.0
NR1D2	9600.0
H2BC13	9599.0
ESRRA	9595.0
ZNF707	9543.0
SKIL	9539.0
NR1I3	9528.0
CTLA4	9505.0
SERPINE1	9495.0
ZNF732	9483.0
PSMC3	9473.0
ZNF3	9435.0
ZNF689	9399.0
MAPK1	9390.0
GATA2	9383.0
ZNF506	9370.0
ZNF250	9362.0
ZNF665	9352.0
COX7A2L	9342.0
NCBP1	9341.0
PSMC1	9330.0
ZNF688	9327.0
ZNF224	9321.0
TAF10	9300.0
NPM1	9296.0
PSMA5	9295.0
LMO2	9274.0
TFAP2C	9222.0
ZNF585B	9216.0
BRPF1	9206.0
YEATS4	9193.0
ZNF429	9183.0
ZNF793	9169.0
HDAC5	9164.0
IL2	9156.0
CCNT2	9153.0
ZNF713	9141.0
AKT1	9135.0
BLK	9130.0
ZNF607	9087.0
TBX5	9086.0
YWHAB	9072.0
ZNF549	9034.0
ZNF774	9013.0
SIN3B	8990.0
MED4	8950.0
H4C2	8932.0
ZNF529	8928.0
SRSF3	8924.0
COX8A	8919.0
U2AF1L4	8894.0
TWIST2	8885.0
ITGAL	8856.0
LAMTOR5	8846.0
LEF1	8818.0
PITX2	8817.0
SRSF7	8813.0
BMP2	8783.0
PHC1	8772.0
NR2F1	8761.0
CDK9	8746.0
HEY2	8718.0
NR1D1	8711.0
RGCC	8686.0
TGIF1	8684.0
NOTCH2	8682.0
TFAP2A	8663.0
ZNF528	8650.0
MYC	8608.0
CHTOP	8590.0
RB1	8587.0
SETD9	8576.0
ZNF681	8572.0
GCK	8571.0
NABP1	8537.0
GPRIN1	8534.0
MED1	8525.0
KCTD15	8512.0
ZNF519	8490.0
PIP4K2C	8473.0
UBE2D3	8435.0
CTSV	8416.0
COX5B	8389.0
NKX3-2	8355.0
HDAC1	8352.0
PAF1	8339.0
CDKN1B	8330.0
ZNF473	8291.0
H2BC9	8277.5
H3C7	8277.5
RAD9B	8271.0
CCNG2	8262.0
RNF34	8259.0
CPSF2	8252.0
LRPPRC	8231.0
JUNB	8209.0
GTF2A1	8199.0
MED10	8179.0
CCNK	8168.0
SMARCD2	8165.0
ZNF708	8146.0
COX5A	8137.0
CPSF6	8128.0
RRAGC	8124.0
ZNF747	8116.0
SNAPC4	8095.0
SSU72	8093.0
ZNF324B	8065.0
ZNF471	8049.0
ZNF660	8039.0
MAPKAPK5	8035.0
CNOT1	8019.0
TP73	7998.0
NPAS4	7997.0
BTG1	7992.0
TCF7L1	7988.0
CPSF3	7982.0
PPARD	7914.0
H2BC12	7877.0
ZNF860	7876.0
ZNF257	7844.0
RORA	7842.0
ZNF510	7838.0
ZNF709	7837.0
ZNF718	7833.0
ZNF839	7825.0
PSME4	7823.0
ARNT2	7810.0
DDIT4	7807.0
ZNF480	7789.0
TP53	7787.0
PRELID1	7783.0
H2AC20	7782.0
NR5A2	7775.0
HAND2	7767.0
ZNF627	7765.0
RPA1	7730.0
ZFP69	7716.0
GADD45A	7566.0
CTSL	7538.0
ANAPC16	7528.0
YWHAZ	7527.0
ZNF483	7515.0
E2F4	7503.0
ZNF398	7489.0
ZNF559	7485.0
PAX5	7482.0
INTS4	7447.0
FOS	7444.0
TEAD3	7406.0
H3-3A	7400.0
KMT2D	7393.0
LMO1	7392.0
CENPJ	7378.0
POLR2L	7368.0
PSMB10	7323.0
ZNF746	7320.0
DPY30	7319.0
PSMD9	7312.0
THOC7	7273.0
HDAC10	7270.0
ITGA4	7264.0
GP1BA	7256.0
ZFP90	7243.0
ZNF211	7226.0
SNRPD3	7220.0
YBX1	7214.0
ZNF606	7212.0
CSTF3	7162.0
MSX2	7152.0
PPM1D	7126.0
H3C10	7119.0
SURF1	7110.0
HIPK2	7106.0
ANAPC7	7099.0
SNRPB	7079.0
ZNF569	7055.0
ZNF17	7054.0
PRKAB2	7036.0
ZNF43	7035.0
TXN	7032.0
RAD51D	7030.0
PPP2R1A	7026.0
CDC26	6995.0
PSMA4	6990.0
SOX2	6978.0
GSR	6953.0
CNOT8	6947.0
ZNF212	6933.0
RAD1	6925.0
APOE	6921.0
CCND3	6916.0
PSMB3	6907.0
CASC3	6900.0
SRSF11	6893.0
SMAD4	6881.0
H2BC4	6860.0
PPP2CA	6858.0
ZNF266	6844.0
ACTL6B	6829.0
H2AC4	6819.0
PPP1R13B	6766.0
CCNH	6764.0
RPS27A	6760.0
MAPK11	6753.0
STUB1	6752.0
TRIAP1	6742.0
PIN1	6725.0
KDM5B	6685.0
ZNF599	6677.0
ZFP14	6676.0
RBBP5	6660.0
INTS13	6653.0
RRAGA	6632.0
ZNF287	6625.0
H2AC8	6620.0
KAT2B	6619.0
CDC25C	6615.0
USP7	6612.0
TEAD2	6605.0
PCNA	6601.0
ZNF584	6593.0
HES1	6570.0
ZNF234	6551.0
PDPK1	6536.0
ALYREF	6525.0
NR2F6	6523.0
PSME3	6499.0
ZKSCAN1	6489.0
POLR2A	6488.0
ZNF555	6472.0
ZNF160	6469.0
SATB2	6446.0
OPRM1	6424.0
STAT1	6376.0
RMI2	6374.0
MDC1	6366.0
ZNF724	6354.0
GEM	6346.5
KCTD1	6340.0
PTPN11	6327.0
PSMB5	6325.0
CHD3	6310.0
CBX3	6302.0
AGRP	6301.0
ATR	6277.0
POLR2G	6258.0
SNAPC5	6241.0
NBN	6237.0
NR1I2	6234.0
NFYA	6231.0
ZNF143	6222.0
ZNF614	6201.0
ZNF490	6200.0
GPI	6199.0
ZNF735	6193.0
ZC3H11A	6182.0
ZNF446	6178.0
VEGFA	6162.0
TXNIP	6157.0
CAV1	6122.0
RSPO3	6116.0
RPRD1B	6110.0
TRIM63	6102.0
VENTX	6075.0
MLST8	6060.0
YAP1	6059.0
DLX6	6054.0
CCND1	6052.0
H2BC11	6041.0
MAX	6038.0
SUPT4H1	6031.0
GAD2	5994.0
ZNF785	5986.0
ZNF12	5969.0
ZNF248	5961.0
RBM8A	5942.0
SMYD2	5938.0
SRSF1	5919.0
ZNF37A	5889.0
ZNF738	5888.0
ZNF677	5859.0
NR2E3	5825.0
STK11	5808.0
LBR	5770.0
HSPD1	5753.0
SARNP	5752.0
GPS2	5731.0
ZNF195	5725.0
CDK12	5712.0
ELL	5695.0
TNRC6A	5686.0
ZNF225	5655.0
INTS14	5639.0
ZNF619	5633.0
GPX2	5627.0
CSTF2T	5609.0
CHD4	5586.0
PCBP4	5577.0
RABGGTA	5568.0
TP53RK	5559.0
SP1	5543.0
PSMD11	5530.0
AURKA	5495.0
H4C6	5474.0
ESRRG	5472.0
ZNF567	5464.0
MGA	5450.0
POLR2C	5449.0
PTEN	5439.0
PRKACA	5434.0
GRIN2A	5420.0
NR1H2	5345.0
CGA	5327.0
ZNF714	5325.0
ZFP69B	5304.0
BDNF	5260.0
NCBP2	5241.0
H4C5	5237.0
ZNF99	5227.0
CRADD	5209.0
MDM2	5154.0
ZNF675	5123.0
IFNG	5120.0
ZNF70	5119.0
ZNF347	5100.0
CAMK2G	5094.0
PPARA	5081.0
SMARCC2	5065.0
ZFP30	5064.0
POLR2I	5052.0
BTG2	5038.0
PINK1	5016.0
PTPN1	5008.0
NR4A3	5006.0
CNOT7	4990.0
L3MBTL2	4984.0
CNOT9	4978.0
TAF3	4963.0
NR3C2	4956.0
CSTF1	4914.0
MYBL2	4912.0
H3-3B	4910.0
ZNF20	4864.0
H4C1	4857.0
SEM1	4832.0
PSME1	4820.0
YWHAH	4796.0
SNAPC3	4795.0
ZNF317	4791.0
BANP	4774.0
ERBB2	4769.0
COX6A1	4760.0
SIN3A	4733.0
ZNF671	4727.0
FOXG1	4716.0
ZC3H8	4713.0
RRM2	4690.0
TP53I3	4673.0
ZNF791	4669.0
ZNF641	4651.0
PSMB8	4635.0
CCNE1	4633.0
E2F5	4629.0
ZNF691	4614.0
SNRPE	4597.0
RBFOX3	4596.0
FANCI	4588.0
ZNF678	4571.0
ZNF320	4558.0
ZNF233	4553.0
TPX2	4550.0
INTS9	4540.0
H2BC17	4528.0
TAF12	4522.0
NFYB	4517.0
TAF13	4505.0
ZNF668	4454.0
INTS2	4452.0
ZNF433	4440.0
NABP2	4360.0
ZNF253	4345.0
CCNB1	4343.0
ZIM2	4338.0
ZNF285	4319.0
COL1A1	4312.0
ZNF595	4297.0
ZNF436	4291.0
ZNF154	4269.0
WWTR1	4268.0
TAF8	4236.0
ANAPC11	4231.0
ZNF34	4214.0
SOCS3	4200.0
EGFR	4196.0
ZKSCAN4	4185.0
TNKS1BP1	4172.0
IL2RA	4129.0
ZNF267	4082.0
ZNF582	4074.0
NLRC4	4051.0
PLXNA4	4039.0
ZNF138	4013.0
ZNF334	3983.0
ZNF23	3977.0
SNAPC2	3967.0
ZNF213	3953.0
RHEB	3933.0
BRD2	3927.0
EPC1	3913.0
RNPS1	3907.0
MSTN	3893.0
PIDD1	3887.0
ITGA5	3882.0
ZSCAN25	3879.0
ZNF564	3856.0
UBE2D1	3827.0
MED13	3816.0
PLAGL1	3806.0
SRSF4	3792.0
GATAD2B	3782.0
TNRC6B	3765.0
ZNF649	3759.0
ZNF700	3748.0
RXRG	3744.0
WDR33	3705.0
UBC	3678.0
SMARCC1	3652.0
CTSK	3643.0
RNMT	3626.0
MED17	3600.0
GTF2E1	3599.0
INTS7	3566.0
CTR9	3541.0
H4C13	3529.0
H2BC21	3526.0
EHMT1	3518.0
POU4F1	3515.0
UBE2S	3510.0
WDR5	3507.0
ZNF566	3503.0
NR6A1	3496.0
GTF2H5	3475.0
TBP	3451.0
NOTCH3	3444.0
ZNF568	3441.0
SMURF2	3435.0
ZNF354B	3415.0
ZNF605	3414.0
AKT2	3403.0
ZNF670	3396.0
ZNF337	3392.0
NELFA	3364.0
NR2C2AP	3353.0
IGFBP3	3334.0
ZNF14	3328.0
PRKCB	3319.0
ZNF382	3316.0
SCO1	3308.0
GAD1	3303.0
H2BC15	3284.0
ZNF175	3283.0
NUDT21	3265.0
JMY	3260.0
ZNF749	3259.0
ZNF692	3258.0
MAML1	3242.0
SRF	3237.0
ZNF804B	3226.0
CPSF1	3225.0
NRBF2	3215.0
H2AC7	3201.5
H2BC7	3201.5
TTC5	3198.0
MSH2	3167.0
ZNF587	3157.0
CNOT3	3107.0
BBC3	3100.0
MIR137	3077.0
POLR2K	3074.0
HNF4G	3042.0
JAG1	3034.0
CHEK1	2999.0
ZNF479	2992.0
GTF2H1	2970.0
TEAD4	2881.0
NR1H4	2879.0
ZNF613	2829.0
PSMA6	2818.0
AFF4	2816.0
SCO2	2779.0
MLH1	2764.0
H4C3	2755.0
SESN2	2737.0
CPSF4	2720.0
CSNK2A2	2708.0
BCL2L14	2705.0
SLC38A9	2696.0
ZNF664	2690.0
YY1	2687.0
ZNF140	2661.0
H2BC5	2649.0
ZNF778	2640.0
MTOR	2633.0
PLK2	2622.0
RTF1	2616.0
CNOT6	2587.0
NOP2	2579.0
CAMK2D	2571.0
CSF1R	2564.0
BCL6	2561.0
CALM1	2514.0
TGIF2	2495.0
MED6	2492.0
GATA4	2489.0
LAMTOR2	2432.0
POLR2B	2415.0
ERCC3	2407.0
ZNF28	2397.0
RAD9A	2390.0
POLR2F	2354.0
KAT5	2338.0
ZNF875	2327.0
ZNF445	2289.0
RFFL	2253.0
ZNF18	2250.0
FANCC	2245.0
ZNF684	2209.0
RARB	2200.0
AXIN1	2182.0
ZNF727	2149.0
SKP1	2126.0
ZNF792	2120.0
AUTS2	2095.0
FASLG	2094.0
ZNF721	2074.0
ZNF773	2053.0
GRIA2	2052.0
MYB	2037.0
ZNF135	2025.0
SMAD3	2022.0
SETD1A	2012.0
GTF2A2	2005.0
NCOR1	2003.0
HIVEP3	2000.0
ZNF655	1986.0
H2AZ2	1985.0
PSMD5	1955.0
PSMC2	1937.0
TCEA1	1915.0
SMARCD3	1912.0
SMAD6	1904.0
PSMB9	1892.0
GLS	1880.0
ZNF235	1872.0
ZNF583	1856.0
BAX	1844.0
PSMD14	1828.0
GATAD2A	1826.0
EAF2	1818.0
CPSF7	1811.0
SLBP	1798.0
CAMK2B	1772.0
KRBOX5	1768.0
PHC2	1764.0
ZNF485	1760.0
ZNF669	1758.0
LIFR	1747.0
PHF20	1746.0
IL3	1745.0
H2AC6	1742.0
PPP1R13L	1727.0
CDK8	1724.0
ZNF616	1703.0
GTF2F2	1694.0
SMURF1	1677.0
ZNF782	1673.0
HDAC9	1652.0
PSMD2	1596.0
RBBP4	1591.0
PPARG	1586.0
RMI1	1580.0
MLLT3	1562.0
ZNF565	1557.0
PRKAG2	1547.0
RBFOX1	1541.0
ZIM3	1536.0
ELOA	1491.0
ZKSCAN7	1480.0
GSK3B	1479.0
ZNF461	1451.0
EHMT2	1444.0
MAF	1414.0
PPP2R5C	1388.0
CTDP1	1379.0
PRMT6	1367.0
ZNF546	1359.0
RORB	1340.0
DYRK2	1334.0
FOXO1	1323.0
LAMTOR4	1310.0
ZNF331	1296.0
ZNF777	1290.0
ING5	1281.0
MRE11	1265.0
TCF7L2	1260.0
GTF2H3	1252.0
ZNF696	1247.0
ZNF540	1243.0
PCGF5	1226.0
SRSF6	1204.0
BMAL1	1179.0
PCF11	1150.0
TRPC3	1116.0
NFATC2	1093.0
PSMB1	1087.0
SNW1	1067.0
TFAP2D	1049.0
CASP10	1018.0
NR3C1	1013.0
DHX38	1005.0
BRD1	996.0
CDK2	982.0
ZNF557	978.0
CNOT2	975.0
BRPF3	971.0
RARA	941.0
HDAC3	930.0
ZNF662	925.0
MED23	913.0
NR4A1	896.0
NFKB1	848.0
ZNF547	779.0
NFE2	770.0
NR2C1	749.0
PRMT1	729.0
ZNF26	712.0
RXRB	703.0
PSMB4	682.0
ZNF680	652.0
BRCA1	650.0
SRC	626.0
TAF5	612.0
NUAK1	603.0
ZNF10	602.0
TP63	571.0
CDK5	570.0
RELA	558.0
NOTCH4	553.0
SNRPG	539.0
EED	535.0
BID	532.0
MOV10	519.0
TAF15	514.0
SGK1	511.0
ZNF776	503.0
CDKN2A	501.0
SUPT5H	475.0
ZKSCAN5	468.0
ZNF256	454.0
TRIM33	450.0
RUNX2	428.0
ZNF2	423.0
PSMB7	389.0
MBD3	375.0
ZNF775	351.0
AGO3	328.0
RPA2	316.0
WRN	301.0
PRMT5	285.0
NFYC	280.0
PPP2R1B	276.0
CSNK2A1	246.0
ACTL6A	230.0
THOC1	220.0
TBL1XR1	188.0
SRSF5	180.0
GTF2B	177.0
ZNF750	141.0
FYTTD1	104.0
MED20	92.0
TAF1L	61.0
DDX39A	48.0
OCLN	46.0
MTA2	45.0
IGFBP1	14.0
NRBP1	-7.0
RFC4	-21.0
PRDX2	-71.0
ZNF626	-92.0
MOBP	-108.0
RHNO1	-112.0
YAF2	-133.0
PBRM1	-137.0
MED7	-145.0
ZNF486	-154.0
MAPKAP1	-165.0
LAMTOR1	-181.0
GLS2	-230.0
SRRM1	-250.0
POLR2E	-304.0
TP53AIP1	-316.0
KCNIP3	-337.0
AGO2	-342.0
PSMD1	-344.0
ZFPM1	-372.0
PAPOLA	-384.0
UBE2I	-397.0
NR1H3	-441.0
CRH	-443.0
CBX5	-459.0
RBPJ	-464.0
TIGAR	-470.0
GRIN2B	-473.0
ZNF273	-484.0
RBL2	-537.0
ARID2	-570.0
ZNF706	-571.0
RICTOR	-581.0
THRB	-582.0
SUPT16H	-602.0
ZNF33A	-623.0
RNF111	-625.0
PSMB11	-633.0
ZNF573	-634.0
ZNF227	-652.0
ZNF25	-653.0
SLC2A3	-656.0
SOD2	-716.0
IHH	-718.0
ZNF383	-741.0
EAF1	-768.0
CBX4	-773.0
NELFCD	-841.0
FKBP5	-852.0
ZNF589	-907.0
PRDX5	-918.0
PF4	-922.0
WWOX	-1017.0
PSMA3	-1034.0
NR0B2	-1073.0
CDK6	-1083.0
CAMK4	-1108.0
ZKSCAN8	-1112.0
GTF2E2	-1152.0
THBS1	-1164.0
ZNF74	-1170.0
TSC2	-1208.0
ANAPC2	-1227.0
ZNF184	-1239.0
ZNF551	-1292.0
NAMPT	-1304.0
MET	-1327.0
ZNF493	-1342.0
ZNF419	-1358.0
ZNF343	-1387.0
RNF2	-1431.0
RPTOR	-1437.0
ZNF563	-1438.0
CDC16	-1479.0
ELOC	-1484.0
ATAD2	-1497.0
POLDIP3	-1499.0
ABL1	-1504.0
AURKB	-1519.0
PRELID3A	-1547.0
RUNX3	-1585.0
ZNF264	-1598.0
ATRIP	-1604.0
SREBF1	-1635.0
H3C1	-1648.0
MED30	-1658.0
CNOT10	-1683.0
NELFB	-1691.0
RNU12	-1695.0
COX20	-1699.0
ZNF556	-1704.0
MAML2	-1723.0
PPM1A	-1845.0
MAML3	-1866.0
SRSF2	-1921.0
ESRRB	-1923.0
ZNF282	-1951.0
CDK13	-1964.0
PSMC6	-1967.0
ZNF324	-1968.0
BCL2L11	-2008.0
PSMD4	-2016.0
ZNF570	-2022.0
COX7C	-2025.0
SESN1	-2067.0
TP53BP2	-2087.0
ZNF610	-2093.0
NOC2L	-2098.0
ZNF30	-2110.0
ZNF492	-2121.0
ZNF133	-2125.0
MEF2C	-2129.0
POLR2D	-2136.0
SMARCA4	-2181.0
ZNF560	-2182.0
ASH2L	-2199.0
FURIN	-2200.0
SUPT6H	-2216.0
ZNF302	-2226.0
ZNF704	-2269.0
PSMD3	-2284.0
PMAIP1	-2322.0
ZNF764	-2329.0
RPA3	-2347.0
INTS11	-2351.0
SETD1B	-2363.0
TAF4B	-2376.0
TFDP1	-2414.0
TOP3A	-2438.0
MNAT1	-2446.0
ZSCAN32	-2465.0
PARP1	-2470.0
INS	-2478.0
PABPN1	-2534.0
CREB1	-2546.0
PSMD6	-2567.0
TJP1	-2573.0
ITCH	-2577.0
SNRPF	-2601.0
FOXO3	-2607.0
KRAS	-2609.0
E2F8	-2617.0
SKI	-2620.0
ZNF200	-2631.0
CYCS	-2645.0
ZNF385A	-2665.0
MED24	-2691.0
ZNF215	-2714.0
CTNNB1	-2732.0
CCNC	-2734.0
SMARCB1	-2736.0
ICE1	-2740.0
PSMA7	-2741.0
H2BC6	-2787.0
UBE2E1	-2788.0
SESN3	-2793.0
RPRD1A	-2804.0
H3C11	-2806.0
GAMT	-2823.0
ZNF268	-2870.0
RPAP2	-2914.0
ATM	-2924.0
U2AF2	-2945.0
TAF11	-2948.0
HUS1	-2958.0
ZNF514	-2961.0
GLI3	-2972.0
H3C4	-2978.0
DNA2	-2984.0
CNOT11	-2986.0
H2AX	-2988.0
SPI1	-3000.0
KCTD6	-3013.0
CASP2	-3018.0
ZNF114	-3034.0
SYMPK	-3052.0
RFC3	-3057.0
PSMF1	-3068.0
DDB2	-3165.0
SLU7	-3180.0
H2BC1	-3185.0
DEK	-3200.0
CDK1	-3232.0
TOPBP1	-3256.0
NR4A2	-3263.0
KMT2C	-3280.0
MED27	-3338.0
H2AZ1	-3340.0
KAT6A	-3347.0
ZNF697	-3370.0
ZNF543	-3388.0
E2F6	-3402.0
MIR132	-3405.0
RING1	-3408.0
EXO1	-3428.0
CDC40	-3439.0
EIF4A3	-3505.0
ZNF771	-3537.0
BRD7	-3545.0
INTS12	-3551.0
KMT2A	-3568.0
PERP	-3618.0
SPP1	-3625.0
MED8	-3653.0
RBL1	-3671.0
BRIP1	-3690.0
PSMB2	-3711.0
TNFRSF10A	-3714.0
MMP13	-3719.0
PLK3	-3739.0
PCGF6	-3742.0
ATF2	-3745.0
RRM2B	-3763.0
ZNF33B	-3768.0
ZNF571	-3776.0
H3C6	-3784.0
BMI1	-3786.0
MED25	-3793.0
MDM4	-3819.0
NELFE	-3844.0
HDAC7	-3850.0
ZNF761	-3871.0
ANAPC5	-3872.0
GTF2F1	-3886.0
TEAD1	-3899.0
ZNF420	-3910.0
APAF1	-3933.0
ZFHX3	-3965.0
PIP4K2A	-4003.0
HDAC2	-4029.0
ZNF550	-4039.0
CARM1	-4075.0
CITED4	-4079.0
ZNF558	-4082.0
RUNX1	-4106.0
TCF3	-4162.0
PSMD12	-4181.0
MED15	-4193.0
H2AJ	-4216.0
MAPK14	-4217.0
H2BC10	-4225.0
PSMD7	-4231.0
NKX2-5	-4232.0
RET	-4257.0
IQSEC3	-4296.0
HTT	-4298.0
CCNA2	-4303.0
PSMC4	-4337.0
ARID1B	-4361.0
H4C16	-4372.0
ZNF786	-4376.0
COX18	-4380.0
CREBBP	-4413.0
LSM11	-4425.0
ZKSCAN3	-4427.0
NCOR2	-4442.0
DDX39B	-4479.0
MED31	-4483.0
YWHAG	-4491.0
RBBP8	-4497.0
WWP1	-4550.0
ZNF615	-4555.0
PRKCQ	-4559.0
CASP6	-4568.0
PPARGC1B	-4571.0
CDC23	-4597.0
THRA	-4621.0
HDAC4	-4630.0
ZNF443	-4649.0
CNOT4	-4652.0
ZNF311	-4657.0
FAS	-4664.0
ZNF112	-4702.0
ZNF611	-4707.0
PRKAA1	-4711.0
NPY	-4724.0
PML	-4728.0
COX11	-4730.0
AKT3	-4731.0
ARNT	-4757.0
MYL9	-4802.0
TXNRD1	-4823.0
INTS6	-4846.0
UBE2C	-4848.0
CCND2	-4863.0
PHAX	-4871.0
RAD50	-4876.0
CDC7	-4877.0
UBB	-4879.0
ZFP1	-4886.0
PGR	-4893.0
ZNF430	-4897.0
ZNF226	-4901.0
RBM14	-4906.0
SMARCD1	-4927.0
CBX2	-4942.0
YWHAE	-4961.0
ZNF202	-4974.0
NEDD4L	-5002.0
TNRC6C	-5013.0
KMT2E	-5032.0
ESR1	-5042.0
INTS1	-5058.0
BNIP3L	-5060.0
GPAM	-5064.0
HNF4A	-5087.0
CLP1	-5203.0
CR1	-5204.0
H4C11	-5213.0
XPO1	-5236.0
ZNF71	-5249.0
ARID1A	-5256.0
PPARGC1A	-5265.0
CEBPB	-5278.0
SMARCA2	-5279.0
HIPK1	-5287.0
ITGBL1	-5305.0
CCNG1	-5316.0
FZR1	-5322.0
ERCC2	-5326.0
COL1A2	-5335.0
CDC27	-5367.0
TCF12	-5372.0
ZNF460	-5388.0
ZNF517	-5390.0
TGFB1	-5394.0
ELL3	-5403.0
ZNF425	-5405.0
ELF2	-5434.0
ARID3A	-5460.0
PRR5	-5481.0
RFC2	-5500.0
PRDX1	-5513.0
ZNF221	-5539.0
ATXN3	-5545.0
TP53INP1	-5573.0
ZNF45	-5598.0
BARD1	-5608.0
PRKAA2	-5624.0
ZNF354A	-5632.0
SMAD2	-5636.0
MED26	-5637.0
FBXW7	-5641.0
SIRT1	-5643.0
CASP1	-5651.0
ANAPC15	-5701.0
ZNF136	-5715.0
ZNF624	-5723.0
TFAP2E	-5724.0
RPRD2	-5728.0
ZFP2	-5734.0
ELL2	-5741.0
INTS8	-5744.0
SFN	-5770.0
YES1	-5778.0
ANAPC4	-5783.0
POU2F1	-5794.0
TGFA	-5802.0
ZNF394	-5820.0
GATA3	-5844.0
MAGOHB	-5870.0
ZFP37	-5884.0
PSMA1	-5911.0
YWHAQ	-5915.0
CUL1	-6004.0
ZNF92	-6023.0
POU2F2	-6043.0
IWS1	-6120.0
NOTCH1	-6124.0
KIT	-6147.0
ZNF548	-6162.0
GTF2H4	-6171.0
PIP4P1	-6181.0
DAXX	-6189.0
INTS10	-6226.0
ZNF169	-6237.0
SYT10	-6254.0
KRBA1	-6265.0
BLM	-6287.0
ZNF699	-6301.0
CAT	-6326.0
E2F1	-6335.0
EZH2	-6349.0
INTS3	-6351.0
H4C4	-6381.0
SERPINB13	-6385.0
SCMH1	-6397.0
MIR27A	-6408.0
RNU4ATAC	-6415.0
PRKAG3	-6417.0
ZNF600	-6437.0
TFDP2	-6465.0
TAF2	-6476.0
FANCD2	-6486.0
DGCR8	-6490.0
TAF7	-6520.0
RXRA	-6528.0
SKIC8	-6548.0
ICE2	-6551.0
EP300	-6560.0
ZNF254	-6610.0
ZNF682	-6632.0
DDIT3	-6649.0
CHEK2	-6654.0
RNGTT	-6664.0
ZNF716	-6679.0
GLI2	-6682.0
ZNF577	-6729.0
PIP4K2B	-6743.0
NDRG1	-6759.0
ABCA6	-6779.0
BIRC5	-6855.0
ZNF521	-6856.0
SNAPC1	-6876.0
TAF4	-6925.0
H2BC14	-6929.0
CBX6	-6979.0
MAP2K6	-7001.0
ZNF710	-7026.0
ZNF274	-7062.0
G6PC1	-7065.0
ZNF350	-7067.0
PHC3	-7127.0
PSMC5	-7244.0
H2AC14	-7300.0
ZNF586	-7323.0
E2F7	-7333.0
IL6	-7357.0
MLLT1	-7374.0
STEAP3	-7393.0
PVALB	-7426.0
ZNF454	-7479.0
COX19	-7486.0
ZNF124	-7519.0
TNFRSF10C	-7568.0
RYBP	-7572.0
LAMTOR3	-7596.0
SUZ12	-7600.0
ZNF726	-7601.0
H3C3	-7636.0
PTPN4	-7645.0
COX6C	-7648.0
ZNF658	-7691.0
SMAD1	-7698.0
ZNF737	-7708.0
SRRT	-7709.0
ZNF100	-7717.0
ZNF554	-7739.0
CBX8	-7760.0
KMT2B	-7801.0
ZNF562	-7815.0
ZNF230	-7816.0
SKP2	-7874.0
MIR24-2	-7875.0
NR5A1	-7888.0
COX16	-7894.0
ZNF799	-7908.0
CDC73	-7975.0
MED16	-8018.0
KAT2A	-8049.0
L3MBTL1	-8067.0
H2BC3	-8138.0
PSMA8	-8172.0
ZNF286A	-8209.0
TNFRSF10B	-8296.0
ZNF679	-8350.0
PRDM7	-8387.0
ELOB	-8397.0
CSF2	-8423.0
TSC1	-8448.0
H3C8	-8543.0
ZNF300	-8560.0
ZNF596	-8562.0
SP7	-8703.0
ZNF730	-8719.0
ELOA2	-8769.0
BGLAP	-8829.0
THOC3	-8903.0
ZNF208	-8951.0
ZNF439	-8958.0
ZNF717	-9188.0

---

REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS

REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS

	720
set	REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS
setSize	39
pANOVA	0.000293
s.dist	-0.335
p.adjustANOVA	0.0283

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TAS2R31	-9161
TAS2R14	-8970
TAS2R7	-8921
TAS2R46	-8864
TAS2R41	-8637
TAS2R20	-8416
TAS2R42	-8382
TAS2R39	-8100
TAS2R1	-8099
TAS1R3	-7487
GPRC6A	-7399
GRM5	-7151
TAS2R50	-7105
TAS2R19	-7068
TAS2R30	-7057
TAS2R4	-6887
TAS2R38	-5975
GRM7	-5447
TAS2R3	-5246
TAS2R5	-4204

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TAS2R31	-9161
TAS2R14	-8970
TAS2R7	-8921
TAS2R46	-8864
TAS2R41	-8637
TAS2R20	-8416
TAS2R42	-8382
TAS2R39	-8100
TAS2R1	-8099
TAS1R3	-7487
GPRC6A	-7399
GRM5	-7151
TAS2R50	-7105
TAS2R19	-7068
TAS2R30	-7057
TAS2R4	-6887
TAS2R38	-5975
GRM7	-5447
TAS2R3	-5246
TAS2R5	-4204
TAS2R40	-3303
TAS1R2	-2677
TAS1R1	-2676
GRM1	-1324
GRM3	548
GRM6	735
GABBR1	807
GRM8	1433
TAS2R10	1942
CASR	2807
TAS2R60	2869
GABBR2	3725
TAS2R16	4532
GRM2	7689
TAS2R13	10349
GRM4	10806
TAS2R8	11217
TAS2R9	11784
TAS2R43	12001

---

REACTOME_NEGATIVE_REGULATION_OF_FGFR1_SIGNALING

REACTOME_NEGATIVE_REGULATION_OF_FGFR1_SIGNALING

	952
set	REACTOME_NEGATIVE_REGULATION_OF_FGFR1_SIGNALING
setSize	32
pANOVA	0.000341
s.dist	0.366
p.adjustANOVA	0.0311

Top enriched genes

Top 20 genes

GeneID	Gene Rank
UBA52	12048
FGF20	11659
PPP2CB	11602
FGF5	10861
MAPK3	10376
FGF22	10147
FGF17	9443
MAPK1	9390
FGF4	8965
FGF9	8830
FGF8	8081
FGF3	7841
KL	7480
FGF6	7242
PPP2R1A	7026
PPP2CA	6858
RPS27A	6760
FGF1	6404
PTPN11	6327
FGF23	5385

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
UBA52	12048
FGF20	11659
PPP2CB	11602
FGF5	10861
MAPK3	10376
FGF22	10147
FGF17	9443
MAPK1	9390
FGF4	8965
FGF9	8830
FGF8	8081
FGF3	7841
KL	7480
FGF6	7242
PPP2R1A	7026
PPP2CA	6858
RPS27A	6760
FGF1	6404
PTPN11	6327
FGF23	5385
FGF10	5079
SPRY2	4430
GRB2	4417
BRAF	4204
UBC	3678
FRS2	1660
FGFR1	835
SRC	626
CBL	-1592
FGF2	-2778
MKNK1	-3811
UBB	-4879

---

REACTOME_SIGNALING_BY_FGFR2

REACTOME_SIGNALING_BY_FGFR2

	957
set	REACTOME_SIGNALING_BY_FGFR2
setSize	72
pANOVA	0.000527
s.dist	0.236
p.adjustANOVA	0.0456

Top enriched genes

Top 20 genes

GeneID	Gene Rank
UBA52	12048
FGF20	11659
PPP2CB	11602
ESRP2	11503
POLR2H	10916
FGF5	10861
HRAS	10478
FGFBP1	10449
MAPK3	10376
FGF22	10147
POLR2J	10004
FGFBP2	9882
FGF17	9443
MAPK1	9390
NCBP1	9341
FGF4	8965
FGF9	8830
FRS3	8566
PLCG1	8474
FGF8	8081

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
UBA52	12048
FGF20	11659
PPP2CB	11602
ESRP2	11503
POLR2H	10916
FGF5	10861
HRAS	10478
FGFBP1	10449
MAPK3	10376
FGF22	10147
POLR2J	10004
FGFBP2	9882
FGF17	9443
MAPK1	9390
NCBP1	9341
FGF4	8965
FGF9	8830
FRS3	8566
PLCG1	8474
FGF8	8081
FGF3	7841
FGFR2	7428
POLR2L	7368
FGF6	7242
PPP2R1A	7026
PPP2CA	6858
FGFBP3	6812
RPS27A	6760
POLR2A	6488
FGF1	6404
PTPN11	6327
POLR2G	6258
TIAL1	6137
POLR2C	5449
FGF23	5385
NCBP2	5241
FGF10	5079
POLR2I	5052
SPRY2	4430
GRB2	4417
BRAF	4204
SHC1	4171
HNRNPA1	4099
PIK3CA	3688
UBC	3678
POLR2K	3074
POLR2B	2415
POLR2F	2354
GTF2F2	1694
FRS2	1660
RBFOX2	1154
HNRNPM	792
ESRP1	658
SRC	626
HNRNPF	593
PIK3R1	517
GAB1	-61
PTBP1	-253
POLR2E	-304
NRAS	-916
TIA1	-1393
CBL	-1592
POLR2D	-2136
KRAS	-2609
FGF2	-2778
MKNK1	-3811
GTF2F1	-3886
SOS1	-4686
UBB	-4879
HNRNPH1	-5197
FGF18	-6573
FGF7	-6850

---

REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES

REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES

	1135
set	REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES
setSize	353
pANOVA	0.000635
s.dist	0.106
p.adjustANOVA	0.0522

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS3A	12354
RPL35	12299
UBA52	12048
RPL7A	11993
NAALAD2	11929
RPS10	11901
PSMD8	11740
HDC	11692
AADAT	11656
AGXT2	11640
MCCC2	11610
RIMKLA	11542
GNMT	11535
PSMB6	11526
PNMT	11362
PSME2	11317
SLC25A44	11135
TAT	11071
SQOR	11060
SEPHS2	11050

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS3A	12354.0
RPL35	12299.0
UBA52	12048.0
RPL7A	11993.0
NAALAD2	11929.0
RPS10	11901.0
PSMD8	11740.0
HDC	11692.0
AADAT	11656.0
AGXT2	11640.0
MCCC2	11610.0
RIMKLA	11542.0
GNMT	11535.0
PSMB6	11526.0
PNMT	11362.0
PSME2	11317.0
SLC25A44	11135.0
TAT	11071.0
SQOR	11060.0
SEPHS2	11050.0
CKB	11043.0
RPL8	10951.0
NAGS	10948.0
TST	10945.0
AGXT	10924.0
RPS14	10917.0
RPL13	10880.0
RPS16	10867.0
MPST	10844.0
PSMD13	10801.0
DBH	10788.0
ENOPH1	10702.0
RPLP0	10491.0
RPS12	10471.0
RPLP1	10423.0
MARS1	10420.0
PSMA2	10419.0
RPSA	10389.0
RPLP2	10388.0
HPD	10373.0
GOT2	10228.0
RPS9	10000.0
HNMT	9936.0
RPL27	9921.0
NMRAL1	9864.0
DAO	9717.0
GLUD1	9645.0
ADO	9635.0
HAAO	9608.0
AFMID	9603.0
RPL19	9586.0
EPRS1	9580.0
RPL10A	9510.0
PSMC3	9473.0
OGDH	9461.0
RPL28	9439.0
RPS26	9398.0
RPL3L	9335.0
PSMC1	9330.0
RPL15	9318.0
PSMA5	9295.0
AGMAT	9241.0
RPS5	9174.0
EEF1E1	9147.0
RPL31	9139.0
GCDH	9022.0
AZIN2	8973.0
OAZ2	8845.0
PYCR3	8837.0
PIPOX	8829.0
SERINC4	8760.0
ECHS1	8724.0
AANAT	8648.0
ASNS	8596.0
ODC1	8577.0
PPM1K	8573.0
TPH1	8540.0
RPS23	8529.0
PRODH2	8387.0
DUOX1	8333.0
RPS15	8328.0
SLC6A11	8255.0
SLC36A4	8243.0
GPT2	8242.0
FAU	8229.0
TDO2	8190.0
DLD	8183.0
RPL7	8155.0
NAT8L	8148.0
RPS13	8147.0
HOGA1	8020.0
RIDA	7958.0
SLC6A7	7893.0
PSME4	7823.0
RPL26L1	7785.0
CDO1	7714.0
BCKDK	7645.0
TPH2	7604.0
FAH	7464.0
IYD	7434.0
SERINC2	7384.0
PYCR2	7380.0
BHMT	7360.0
RPS11	7339.0
PSMB10	7323.0
PSMD9	7312.0
RPL22L1	7254.0
CKM	7195.0
RPL14	7148.0
RPS6	7103.0
RPL18	7051.0
RPL32	7038.0
DDC	7024.0
PSMA4	6990.0
RPL27A	6977.0
DLAT	6974.0
GSR	6953.0
PSMB3	6907.0
RPL3	6848.0
GCSH	6846.0
SRM	6778.0
RPS27A	6760.0
ASRGL1	6504.0
PSME3	6499.0
RPL6	6436.0
PSMB5	6325.0
HYKK	6270.0
SERINC3	6147.0
ASS1	5982.0
MTR	5873.0
RPS27L	5802.0
SARDH	5757.0
RPL5	5746.0
KARS1	5663.0
GLDC	5557.0
DUOX2	5549.0
PYCR1	5535.0
PSMD11	5530.0
RPL36	5497.0
RPS18	5479.0
RPL12	5445.0
CGA	5327.0
KYAT1	5292.0
PAPSS1	5262.0
PSPH	5146.0
OAT	5043.0
RPL38	5039.0
CPS1	4996.0
NNMT	4911.0
RPL13A	4893.5
AMT	4870.0
SEM1	4832.0
PSME1	4820.0
OAZ3	4804.0
CRYM	4802.0
TXN2	4781.0
ETHE1	4722.0
SLC25A13	4703.0
RPS8	4682.0
ALDH18A1	4664.0
PSMB8	4635.0
DARS1	4591.0
RPS15A	4574.0
PHYKPL	4499.0
RPS20	4493.0
RPL35A	4324.0
SLC3A2	4318.0
BCAT2	4295.0
RPS25	3868.0
PXMP2	3852.0
ARG2	3849.0
SMOX	3808.0
IL4I1	3804.0
LIPT2	3719.0
PRODH	3650.0
GADL1	3501.0
RPL41	3483.0
RPL18A	3298.0
RPL23	3249.0
RARS1	3123.0
DIO3	3090.0
PSAT1	2859.0
SLC44A1	2828.0
CARNS1	2820.0
PSMA6	2818.0
SLC5A5	2811.0
EEFSEC	2669.0
GCAT	2507.0
AHCY	2389.0
TSTD1	2188.0
AUH	2174.0
SERINC1	2144.0
SLC25A21	2132.0
KMO	2123.0
RPL17	2047.0
PSMD5	1955.0
PSMC2	1937.0
RPL23A	1900.0
PSMB9	1892.0
SLC25A10	1890.0
GLS	1880.0
PSMD14	1828.0
SLC7A5	1787.0
AIMP1	1775.0
SLC6A12	1763.0
CSAD	1721.0
PAPSS2	1608.0
PSMD2	1596.0
RPS7	1574.0
RPS28	1519.0
AMD1	1417.0
IARS1	1292.0
GRHPR	1276.0
MTRR	1258.0
UROC1	1155.0
PSMB1	1087.0
GATM	1062.0
HIBADH	980.0
RPL10L	887.0
LARS1	883.0
ASPA	763.0
ASPG	751.0
RPL21	717.0
PSMB4	682.0
ACMSD	642.0
SHMT1	516.0
PCBD1	490.0
PSMB7	389.0
SDS	223.0
SRR	59.0
RPL22	19.0
RPL36AL	-101.5
RPL24	-132.0
DCT	-178.0
GLS2	-230.0
DIO2	-242.0
KYNU	-343.0
PSMD1	-344.0
OAZ1	-467.0
GPT	-617.0
PSMB11	-633.0
DIO1	-686.0
QDPR	-695.0
RPL30	-725.0
NQO1	-842.0
PSTK	-876.0
RPL34	-891.0
HAL	-902.0
BCKDHB	-1016.0
BCAT1	-1023.0
PSMA3	-1034.0
TH	-1256.0
PAOX	-1276.0
RPS19	-1286.0
RPS27	-1469.0
GSTZ1	-1518.0
RPL37A	-1652.0
IVD	-1748.0
OCA2	-1802.0
HIBCH	-1841.0
RPL29	-1880.0
PAH	-1887.0
DBT	-1888.0
ALDH9A1	-1895.0
PSMC6	-1967.0
SEPSECS	-1998.0
LIAS	-2012.0
PSMD4	-2016.0
SCLY	-2081.0
DHTKD1	-2230.0
PSMD3	-2284.0
PSMD6	-2567.0
RPS2	-2570.0
RPS29	-2664.0
PSMA7	-2741.0
GAMT	-2823.0
RPL4	-2829.0
RIMKLB	-2842.0
RPL37	-3007.0
RPL11	-3010.0
PSMF1	-3068.0
ALDH7A1	-3106.0
ALDH6A1	-3205.0
LIPT1	-3278.0
ACAT1	-3281.0
BBOX1	-3487.0
INMT	-3520.0
GOT1	-3536.0
BCKDHA	-3539.0
PSMB2	-3711.0
ADI1	-3726.0
CHDH	-3818.0
MCCC1	-3993.0
RPS21	-4136.0
PSMD12	-4181.0
PSMD7	-4231.0
RPL26	-4270.0
TYR	-4295.0
IDO1	-4305.0
FMO1	-4317.0
PSMC4	-4337.0
PDHB	-4367.0
MRI1	-4374.0
CTH	-4527.0
ASL	-4548.0
DLST	-4566.0
KYAT3	-4587.0
AASS	-4618.0
RPS3	-4641.0
ALDH4A1	-4710.0
ACADSB	-4816.0
TXNRD1	-4823.0
BHMT2	-4834.0
PHGDH	-4904.0
SECISBP2	-5000.0
RPL9	-5020.0
SDSL	-5073.0
TPO	-5275.0
AZIN1	-5321.0
CKMT2	-5402.0
DMGDH	-5721.0
GLUL	-5769.0
SLC25A12	-5903.0
PSMA1	-5911.0
HAO1	-5977.0
ACAD8	-5978.0
IDO2	-6021.0
CARNMT1	-6061.0
PDHA2	-6111.0
SERINC5	-6269.0
PDHX	-6328.0
RPL39L	-6470.0
AIMP2	-6842.0
APIP	-7024.0
ARG1	-7025.0
FOLH1	-7058.0
AMDHD1	-7106.0
RPS24	-7143.0
CKMT1B	-7183.0
MAT1A	-7196.0
PSMC5	-7244.0
HGD	-7431.0
SUOX	-7442.0
NDUFAB1	-7605.0
SLC45A2	-7670.0
FTCD	-7690.0
SLC25A2	-7712.0
TSHB	-7730.0
MTAP	-7758.0
TYRP1	-7797.0
PSMA8	-8172.0
DDO	-8208.0
SLC25A15	-8359.0

---

REACTOME_CELLULAR_RESPONSE_TO_STARVATION

REACTOME_CELLULAR_RESPONSE_TO_STARVATION

	1582
set	REACTOME_CELLULAR_RESPONSE_TO_STARVATION
setSize	147
pANOVA	0.0012
s.dist	0.155
p.adjustANOVA	0.0909

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS3A	12354
RPL35	12299
UBA52	12048
RPL7A	11993
RPS10	11901
GCN1	11673
RPL8	10951
RPS14	10917
RPL13	10880
RRAGD	10877
RPS16	10867
RPLP0	10491
RPS12	10471
RPLP1	10423
RPSA	10389
RPLP2	10388
RPS9	10000
RPL27	9921
RPL19	9586
RPL10A	9510

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS3A	12354.0
RPL35	12299.0
UBA52	12048.0
RPL7A	11993.0
RPS10	11901.0
GCN1	11673.0
RPL8	10951.0
RPS14	10917.0
RPL13	10880.0
RRAGD	10877.0
RPS16	10867.0
RPLP0	10491.0
RPS12	10471.0
RPLP1	10423.0
RPSA	10389.0
RPLP2	10388.0
RPS9	10000.0
RPL27	9921.0
RPL19	9586.0
RPL10A	9510.0
ATP6V1C1	9459.0
RPL28	9439.0
RPS26	9398.0
RPL3L	9335.0
RPL15	9318.0
ITFG2	9304.0
SEH1L	9275.0
RPS5	9174.0
RPL31	9139.0
MIOS	8980.0
LAMTOR5	8846.0
ASNS	8596.0
RPS23	8529.0
SEC13	8518.0
NPRL2	8363.0
RPS15	8328.0
EIF2S1	8314.0
FAU	8229.0
ATP6V1B1	8164.0
RPL7	8155.0
RPS13	8147.0
RRAGC	8124.0
RPL26L1	7785.0
ATP6V1G2	7612.0
IMPACT	7456.0
RPS11	7339.0
RPL22L1	7254.0
RPL14	7148.0
KPTN	7104.0
RPS6	7103.0
RPL18	7051.0
RPL32	7038.0
RPL27A	6977.0
RPL3	6848.0
RPS27A	6760.0
RRAGA	6632.0
RPL6	6436.0
ATP6V1E1	6184.0
MLST8	6060.0
RPS27L	5802.0
RPL5	5746.0
RPL36	5497.0
RPS18	5479.0
RPL12	5445.0
FNIP1	5365.0
RPL38	5039.0
RPL13A	4893.5
RPS8	4682.0
RPS15A	4574.0
ATP6V1D	4573.0
RPS20	4493.0
RPL35A	4324.0
EIF2AK4	4279.0
RHEB	3933.0
ATP6V1G3	3921.0
RPS25	3868.0
WDR59	3820.0
NPRL3	3756.0
TRIB3	3680.0
RPL41	3483.0
RPL18A	3298.0
RPL23	3249.0
SESN2	2737.0
SLC38A9	2696.0
ATP6V0E2	2666.0
MTOR	2633.0
LAMTOR2	2432.0
RPL17	2047.0
ATP6V1F	2009.0
RPL23A	1900.0
RPS7	1574.0
RPS28	1519.0
ATF4	1438.0
LAMTOR4	1310.0
KICS2	1277.0
RPL10L	887.0
RPL21	717.0
DEPDC5	491.0
ATF3	25.0
RPL22	19.0
ATP6V0D2	-20.0
FLCN	-94.0
RPL36AL	-101.5
RPL24	-132.0
LAMTOR1	-181.0
ATP6V0D1	-460.0
RPL30	-725.0
RPL34	-891.0
WDR24	-945.0
CASTOR1	-1013.0
ATP6V1C2	-1221.0
RPS19	-1286.0
ATP6V0C	-1320.0
ATP6V1B2	-1330.0
RPTOR	-1437.0
RPS27	-1469.0
RPL37A	-1652.0
RPL29	-1880.0
SESN1	-2067.0
ATP6V1H	-2408.0
RPS2	-2570.0
RPS29	-2664.0
ATP6V0B	-2813.0
RPL4	-2829.0
RPL37	-3007.0
RPL11	-3010.0
CEBPG	-3612.0
ATP6V1G1	-3670.0
ATF2	-3745.0
SH3BP4	-4024.0
RPS21	-4136.0
RPL26	-4270.0
RPS3	-4641.0
SZT2	-4860.0
ATP6V1A	-4925.0
EIF2S2	-4933.0
RPL9	-5020.0
CEBPB	-5278.0
TCIRG1	-5743.0
RPL39L	-6470.0
DDIT3	-6649.0
FNIP2	-6986.0
RPS24	-7143.0
LAMTOR3	-7596.0
BMT2	-7892.0
ATP6V1E2	-8149.0
ATP6V0E1	-8365.0

---

REACTOME_SIGNALING_BY_FGFR1

REACTOME_SIGNALING_BY_FGFR1

	956
set	REACTOME_SIGNALING_BY_FGFR1
setSize	49
pANOVA	0.00127
s.dist	0.266
p.adjustANOVA	0.0909

Top enriched genes

Top 20 genes

GeneID	Gene Rank
UBA52	12048
FGF20	11659
PPP2CB	11602
FLRT1	11382
SPRED1	11131
FGF5	10861
HRAS	10478
MAPK3	10376
FGF22	10147
FGF17	9443
MAPK1	9390
FGF4	8965
FGF9	8830
FRS3	8566
PLCG1	8474
FGF8	8081
FGF3	7841
KL	7480
FGF6	7242
PPP2R1A	7026

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
UBA52	12048
FGF20	11659
PPP2CB	11602
FLRT1	11382
SPRED1	11131
FGF5	10861
HRAS	10478
MAPK3	10376
FGF22	10147
FGF17	9443
MAPK1	9390
FGF4	8965
FGF9	8830
FRS3	8566
PLCG1	8474
FGF8	8081
FGF3	7841
KL	7480
FGF6	7242
PPP2R1A	7026
PPP2CA	6858
RPS27A	6760
FGF1	6404
PTPN11	6327
FGF23	5385
FGF10	5079
SPRY2	4430
GRB2	4417
BRAF	4204
SHC1	4171
PIK3CA	3688
UBC	3678
FGFRL1	2806
FRS2	1660
SPRED2	1315
FGFR1	835
SRC	626
PIK3R1	517
FLRT2	110
GAB1	-61
NRAS	-916
CBL	-1592
KRAS	-2609
FGF2	-2778
FLRT3	-3549
MKNK1	-3811
SOS1	-4686
UBB	-4879
FGF18	-6573

---

REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION

REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION

	309
set	REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION
setSize	15
pANOVA	0.00127
s.dist	0.48
p.adjustANOVA	0.0909

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FGF20	11659
FGF5	10861
FGF22	10147
FGF17	9443
FGF4	8965
FGF9	8830
FGF8	8081
FGF3	7841
KL	7480
FGF6	7242
FGF1	6404
FGF23	5385
FGF10	5079
FGFR1	835
FGF2	-2778

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FGF20	11659
FGF5	10861
FGF22	10147
FGF17	9443
FGF4	8965
FGF9	8830
FGF8	8081
FGF3	7841
KL	7480
FGF6	7242
FGF1	6404
FGF23	5385
FGF10	5079
FGFR1	835
FGF2	-2778

---

REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S

REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S

	1150
set	REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S
setSize	53
pANOVA	0.00137
s.dist	0.254
p.adjustANOVA	0.0941

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS3A	12354
RPS10	11901
EIF4EBP1	11318
RPS14	10917
RPS16	10867
RPS12	10471
RPSA	10389
RPS9	10000
RPS26	9398
RPS5	9174
EIF3K	9021
PABPC1	8770
EIF3J	8716
RPS23	8529
RPS15	8328
EIF2S1	8314
FAU	8229
EIF3D	8186
EIF3B	8149
RPS13	8147

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS3A	12354
RPS10	11901
EIF4EBP1	11318
RPS14	10917
RPS16	10867
RPS12	10471
RPSA	10389
RPS9	10000
RPS26	9398
RPS5	9174
EIF3K	9021
PABPC1	8770
EIF3J	8716
RPS23	8529
RPS15	8328
EIF2S1	8314
FAU	8229
EIF3D	8186
EIF3B	8149
RPS13	8147
EIF3L	8102
RPS11	7339
RPS6	7103
RPS27A	6760
EIF4A2	6083
RPS27L	5802
RPS18	5479
EIF4A1	4687
RPS8	4682
EIF4B	4666
EIF3F	4624
RPS15A	4574
RPS20	4493
EIF4E	4141
RPS25	3868
EIF4G1	2605
RPS7	1574
RPS28	1519
EIF3M	1389
EIF3A	730
EIF3H	-98
EIF3E	-1039
EIF3G	-1094
RPS19	-1286
RPS27	-1469
EIF3I	-1737
RPS2	-2570
RPS29	-2664
RPS21	-4136
RPS3	-4641
EIF2S2	-4933
RPS24	-7143
EIF4H	-8086

---

REACTOME_STRIATED_MUSCLE_CONTRACTION

REACTOME_STRIATED_MUSCLE_CONTRACTION

	653
set	REACTOME_STRIATED_MUSCLE_CONTRACTION
setSize	35
pANOVA	0.0019
s.dist	0.303
p.adjustANOVA	0.124

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TNNI1	12391
MYH8	12085
TPM3	12043
TNNC1	11963
TNNT1	11936
TNNI3	11925
MYL2	11511
TCAP	10535
TNNC2	10171
MYL4	9997
DES	9701
ACTC1	8893
TMOD2	8316
ACTA1	8264
TNNT2	7680
TMOD3	7471
MYBPC1	7365
VIM	6135
TPM4	5885
MYBPC3	4780

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TNNI1	12391
MYH8	12085
TPM3	12043
TNNC1	11963
TNNT1	11936
TNNI3	11925
MYL2	11511
TCAP	10535
TNNC2	10171
MYL4	9997
DES	9701
ACTC1	8893
TMOD2	8316
ACTA1	8264
TNNT2	7680
TMOD3	7471
MYBPC1	7365
VIM	6135
TPM4	5885
MYBPC3	4780
TPM1	4048
MYL1	2725
MYL3	2547
TNNI2	2018
MYH6	1490
ACTN3	1458
TPM2	1272
TMOD1	531
TNNT3	-188
ACTN2	-756
MYBPC2	-1051
TMOD4	-5368
TTN	-5963
MYH3	-6447
NEB	-7511

---

REACTOME_NEGATIVE_REGULATION_OF_FGFR2_SIGNALING

REACTOME_NEGATIVE_REGULATION_OF_FGFR2_SIGNALING

	953
set	REACTOME_NEGATIVE_REGULATION_OF_FGFR2_SIGNALING
setSize	33
pANOVA	0.00202
s.dist	0.31
p.adjustANOVA	0.124

Top enriched genes

Top 20 genes

GeneID	Gene Rank
UBA52	12048
FGF20	11659
PPP2CB	11602
FGF5	10861
MAPK3	10376
FGF22	10147
FGF17	9443
MAPK1	9390
FGF4	8965
FGF9	8830
FGF8	8081
FGF3	7841
FGFR2	7428
FGF6	7242
PPP2R1A	7026
PPP2CA	6858
RPS27A	6760
FGF1	6404
PTPN11	6327
FGF23	5385

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
UBA52	12048
FGF20	11659
PPP2CB	11602
FGF5	10861
MAPK3	10376
FGF22	10147
FGF17	9443
MAPK1	9390
FGF4	8965
FGF9	8830
FGF8	8081
FGF3	7841
FGFR2	7428
FGF6	7242
PPP2R1A	7026
PPP2CA	6858
RPS27A	6760
FGF1	6404
PTPN11	6327
FGF23	5385
FGF10	5079
SPRY2	4430
GRB2	4417
BRAF	4204
UBC	3678
FRS2	1660
SRC	626
CBL	-1592
FGF2	-2778
MKNK1	-3811
UBB	-4879
FGF18	-6573
FGF7	-6850

---

REACTOME_ERKS_ARE_INACTIVATED

REACTOME_ERKS_ARE_INACTIVATED

	396
set	REACTOME_ERKS_ARE_INACTIVATED
setSize	13
pANOVA	0.00203
s.dist	0.494
p.adjustANOVA	0.124

Top enriched genes

Top 20 genes

GeneID	Gene Rank
VRK3	11890
DUSP7	11638
PPP2CB	11602
MAPK3	10376
PPP2R5D	9622
MAPK1	9390
DUSP3	8303
PPP2R1A	7026
PPP2CA	6858
MAPK7	5876
DUSP4	5253
PPP2R1B	276
DUSP6	-4725

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
VRK3	11890
DUSP7	11638
PPP2CB	11602
MAPK3	10376
PPP2R5D	9622
MAPK1	9390
DUSP3	8303
PPP2R1A	7026
PPP2CA	6858
MAPK7	5876
DUSP4	5253
PPP2R1B	276
DUSP6	-4725

---

REACTOME_FGFR2_LIGAND_BINDING_AND_ACTIVATION

REACTOME_FGFR2_LIGAND_BINDING_AND_ACTIVATION

	308
set	REACTOME_FGFR2_LIGAND_BINDING_AND_ACTIVATION
setSize	19
pANOVA	0.00211
s.dist	0.407
p.adjustANOVA	0.124

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FGF20	11659
FGF5	10861
FGFBP1	10449
FGF22	10147
FGFBP2	9882
FGF17	9443
FGF4	8965
FGF9	8830
FGF8	8081
FGF3	7841
FGFR2	7428
FGF6	7242
FGFBP3	6812
FGF1	6404
FGF23	5385
FGF10	5079
FGF2	-2778
FGF18	-6573
FGF7	-6850

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FGF20	11659
FGF5	10861
FGFBP1	10449
FGF22	10147
FGFBP2	9882
FGF17	9443
FGF4	8965
FGF9	8830
FGF8	8081
FGF3	7841
FGFR2	7428
FGF6	7242
FGFBP3	6812
FGF1	6404
FGF23	5385
FGF10	5079
FGF2	-2778
FGF18	-6573
FGF7	-6850

---

REACTOME_NEGATIVE_REGULATION_OF_FGFR4_SIGNALING

REACTOME_NEGATIVE_REGULATION_OF_FGFR4_SIGNALING

	955
set	REACTOME_NEGATIVE_REGULATION_OF_FGFR4_SIGNALING
setSize	30
pANOVA	0.00256
s.dist	0.318
p.adjustANOVA	0.145

Top enriched genes

Top 20 genes

GeneID	Gene Rank
UBA52	12048
FGF20	11659
PPP2CB	11602
MAPK3	10376
FGF17	9443
MAPK1	9390
FGF4	8965
FGF9	8830
FGF19	8372
FGF8	8081
FGFR4	7821
FGF6	7242
PPP2R1A	7026
PPP2CA	6858
RPS27A	6760
FGF1	6404
PTPN11	6327
KLB	5388
FGF23	5385
SPRY2	4430

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
UBA52	12048
FGF20	11659
PPP2CB	11602
MAPK3	10376
FGF17	9443
MAPK1	9390
FGF4	8965
FGF9	8830
FGF19	8372
FGF8	8081
FGFR4	7821
FGF6	7242
PPP2R1A	7026
PPP2CA	6858
RPS27A	6760
FGF1	6404
PTPN11	6327
KLB	5388
FGF23	5385
SPRY2	4430
GRB2	4417
BRAF	4204
UBC	3678
FRS2	1660
SRC	626
CBL	-1592
FGF2	-2778
MKNK1	-3811
UBB	-4879
FGF18	-6573

---

REACTOME_GLUCURONIDATION

REACTOME_GLUCURONIDATION

	146
set	REACTOME_GLUCURONIDATION
setSize	23
pANOVA	0.00283
s.dist	-0.36
p.adjustANOVA	0.154

Top enriched genes

Top 20 genes

GeneID	Gene Rank
UGT2B7	-7458
UGT2B11	-7438
UGT1A5	-6868
UGT1A3	-6837
UGT1A4	-6695
UGT3A1	-6411
ABHD10	-6242
UGT1A7	-6076
UGT1A9	-5896
UGT1A6	-5416
UGT1A10	-5360
UGT1A8	-5194
UGT2A3	-5186
UGDH	-4268
UGT1A1	-3083
UGT2B15	-1246
UGT2B4	726
UGT2A1	1622
UGT2A2	3241
SLC35D1	6265

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
UGT2B7	-7458
UGT2B11	-7438
UGT1A5	-6868
UGT1A3	-6837
UGT1A4	-6695
UGT3A1	-6411
ABHD10	-6242
UGT1A7	-6076
UGT1A9	-5896
UGT1A6	-5416
UGT1A10	-5360
UGT1A8	-5194
UGT2A3	-5186
UGDH	-4268
UGT1A1	-3083
UGT2B15	-1246
UGT2B4	726
UGT2A1	1622
UGT2A2	3241
SLC35D1	6265
UGP2	7423
UGT3A2	9150
UGT2B17	10564

---

REACTOME_DEVELOPMENTAL_BIOLOGY

REACTOME_DEVELOPMENTAL_BIOLOGY

	76
set	REACTOME_DEVELOPMENTAL_BIOLOGY
setSize	1115
pANOVA	0.00317
s.dist	0.0524
p.adjustANOVA	0.154

Top enriched genes

Top 20 genes

GeneID	Gene Rank
KRT16	12728
LCE1A	12692
LCE2C	12682
KRTAP4-11	12646
TUBA3D	12586
KRTAP10-12	12557
KRTAP10-7	12537
MED11	12513
ADIRF	12489
LIPM	12480
KRTAP5-11	12467
KRTAP13-4	12444
H2BC26	12438
FOXH1	12383
KRTAP12-4	12381
RPS3A	12354
KRTAP6-3	12334
LCE1F	12326
CAP2	12317
RPL35	12299

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
KRT16	12728.0
LCE1A	12692.0
LCE2C	12682.0
KRTAP4-11	12646.0
TUBA3D	12586.0
KRTAP10-12	12557.0
KRTAP10-7	12537.0
MED11	12513.0
ADIRF	12489.0
LIPM	12480.0
KRTAP5-11	12467.0
KRTAP13-4	12444.0
H2BC26	12438.0
FOXH1	12383.0
KRTAP12-4	12381.0
RPS3A	12354.0
KRTAP6-3	12334.0
LCE1F	12326.0
CAP2	12317.0
RPL35	12299.0
LCE5A	12277.0
KRTAP17-1	12248.0
SPRR1B	12223.0
KRTAP4-7	12089.0
H3C2	12075.0
KRT19	12074.0
MSGN1	12050.0
UBA52	12048.0
KRT1	12033.0
RPL7A	11993.0
TUBB1	11981.0
KRTAP12-3	11946.0
KRTAP9-3	11933.0
RPS10	11901.0
FOXD3	11863.0
MESP2	11844.0
H2AC18	11842.5
H2AC19	11842.5
IVL	11814.0
PCGF2	11783.0
CLDN7	11775.0
PSMD8	11740.0
NEUROD1	11691.0
KRT39	11680.0
MED22	11637.0
ACVR1B	11606.0
KLF4	11595.0
PRDM14	11574.0
KRT15	11565.0
TNF	11561.0
KRT31	11540.0
PSMB6	11526.0
TAL1	11501.0
PCK1	11497.0
EOMES	11496.0
KRTAP5-10	11474.0
NKX2-2	11441.0
KRTAP10-10	11433.0
LDB1	11419.0
KRTAP2-1	11416.0
KRTAP21-1	11369.0
RBX1	11330.0
PSME2	11317.0
CYP51A1	11309.0
ITGA10	11308.0
FOXL2	11297.0
TLN1	11256.0
CDK5R1	11233.0
ACVR2B	11224.0
INSM1	11213.0
MAGOH	11202.0
SOX9	11195.0
KRTAP19-1	11177.0
KRT33A	11155.0
KRT82	11153.0
MED28	11151.0
KRT81	11132.0
MAPK13	11116.0
STX1B	11067.0
EFNA4	11066.0
LHX9	11055.0
KRTAP27-1	11039.0
WNT3A	11036.0
FOXA2	11031.0
ANGPTL4	10993.0
PFN1	10987.0
KRT18	10963.0
LCE1B	10960.0
RPL8	10951.0
H4C12	10931.0
RPS14	10917.0
POLR2H	10916.0
LGI3	10910.0
PRKACG	10893.0
RPL13	10880.0
RPS16	10867.0
NKX6-1	10821.0
KRT23	10817.0
CNTNAP1	10803.0
PSMD13	10801.0
ADIPOQ	10781.0
NOTO	10764.0
DLL1	10762.0
KRTAP16-1	10695.0
HOXA1	10644.0
TUBB4B	10619.0
IL6R	10618.0
NTN3	10617.0
EPHB1	10595.0
TUBB2B	10586.0
JUN	10584.0
ITGA2B	10549.0
LCE3E	10544.0
SPRR3	10542.0
HOXA2	10510.0
KRT38	10507.0
RPLP0	10491.0
HRAS	10478.0
CBFB	10474.0
RPS12	10471.0
RPLP1	10423.0
PSMA2	10419.0
GATA6	10410.0
MPZ	10401.0
RPSA	10389.0
RPLP2	10388.0
MAPK3	10376.0
NOG	10341.0
ACTR3	10305.0
POU3F1	10283.0
CDX2	10250.0
HOXD3	10233.0
H4C8	10222.0
KRT14	10187.0
H4C9	10176.0
SHC3	10168.0
CSNK2B	10153.0
CDKN1A	10113.0
SIAH2	10111.0
KRTAP5-8	10075.0
TCF7	10062.0
TIAM1	10051.0
HNF1B	10045.0
RARG	10022.0
POLR2J	10004.0
RPS9	10000.0
H2BC8	9970.0
ST8SIA2	9956.0
RGMB	9949.0
GFRA4	9943.0
RPL27	9921.0
NR2F2	9914.0
TRPC1	9912.0
SALL4	9874.0
FOXA1	9851.0
DRAP1	9841.0
CDK4	9809.0
SEMA7A	9743.0
PAK6	9661.0
DOK4	9647.0
H3C12	9636.0
GFRA1	9626.0
H2BC13	9599.0
RPL19	9586.0
DOK5	9522.0
RAP1GAP	9511.0
RPL10A	9510.0
SRGAP2	9503.0
LGI1	9498.0
PSMC3	9473.0
DOK2	9457.0
RPL28	9439.0
KRT35	9409.0
RPS26	9398.0
MAPK1	9390.0
PITPNA	9385.0
GATA2	9383.0
KRT78	9372.0
NCBP1	9341.0
RPL3L	9335.0
PSMC1	9330.0
RPL15	9318.0
PSMA5	9295.0
TUBA1B	9290.0
ARPC5	9287.0
PDX1	9227.0
WNT10B	9179.0
RPS5	9174.0
RPL31	9139.0
AKT1	9135.0
HMGCR	9105.0
EFNA1	9102.0
RGMA	9085.0
EPHA5	9049.0
KRTAP10-5	8995.0
EPHA2	8983.0
KLK14	8981.0
MED4	8950.0
ISL1	8947.0
PKLR	8938.0
H4C2	8932.0
LCE2A	8901.0
SPINK9	8849.0
SHTN1	8847.0
FGF9	8830.0
LEF1	8818.0
KRT80	8785.0
COL2A1	8777.0
PABPC1	8770.0
EFNA3	8767.0
EVL	8766.0
CDSN	8750.0
TUBB6	8725.0
SALL1	8645.0
PAGR1	8634.0
KRTAP10-1	8632.0
MYC	8608.0
KRT74	8602.0
GCK	8571.0
CACNG4	8544.0
RPS23	8529.0
MED1	8525.0
GRIN1	8502.0
ENAH	8495.0
HOXD1	8494.0
PLCG1	8474.0
PKNOX1	8447.0
COL4A4	8350.0
SDC2	8332.0
RPS15	8328.0
CAPNS1	8292.0
CXCL12	8287.0
USP33	8280.0
H2BC9	8277.5
H3C7	8277.5
MAPK12	8274.0
ITGB3	8268.0
GIT1	8254.0
FAU	8229.0
MED10	8179.0
CXCR4	8156.0
RPL7	8155.0
ARPC3	8153.0
RPS13	8147.0
ACVR1C	8134.0
FLG	8121.0
RPTN	8113.0
MED29	8103.0
EFNA5	8090.0
KRT4	8074.0
COL5A2	8054.0
AP2M1	8022.0
TGM1	8015.0
H2BC12	7877.0
CDH15	7855.0
PSME4	7823.0
SPAG9	7822.0
LIN28A	7794.0
RPL26L1	7785.0
H2AC20	7782.0
NR5A2	7775.0
CFL1	7763.0
SLIT1	7744.0
KRTAP20-1	7653.0
CUL2	7630.0
KRTAP10-6	7621.0
COL6A1	7577.0
CACNA1I	7542.0
KRT8	7540.0
PTF1A	7432.0
ST8SIA4	7430.0
CACNG3	7415.0
TBXT	7407.0
H3-3A	7400.0
KMT2D	7393.0
POLR2L	7368.0
RPS11	7339.0
PSMB10	7323.0
PSMD9	7312.0
RPL22L1	7254.0
KRT2	7193.0
MIXL1	7178.0
RPL14	7148.0
KRT71	7137.0
H3C10	7119.0
KRT32	7108.0
PPL	7105.0
RPS6	7103.0
VLDLR	7097.0
SNAI1	7088.0
RPL18	7051.0
RPL32	7038.0
KRT34	7028.0
PSMA4	6990.0
SOX2	6978.0
RPL27A	6977.0
RASA1	6976.0
FOXA3	6938.0
CACNB2	6919.0
CCND3	6916.0
KRTAP21-3	6915.0
PSEN2	6913.0
PSMB3	6907.0
CASC3	6900.0
SMAD4	6881.0
RAC1	6880.0
LGI2	6872.0
ONECUT1	6863.0
H2BC4	6860.0
KRTAP9-9	6854.0
RPL3	6848.0
LCE2D	6847.0
COL4A3	6840.0
H2AC4	6819.0
HOXA3	6806.0
RFX6	6800.0
DHH	6775.0
RPS27A	6760.0
MAPK11	6753.0
KRTAP5-2	6730.0
GDNF	6723.0
EPHB2	6687.0
FOXF1	6675.0
RBBP5	6660.0
DSC2	6631.0
H2AC8	6620.0
KAT2B	6619.0
ADAM11	6606.0
TEAD2	6605.0
HES1	6570.0
RANBP9	6549.0
PSME3	6499.0
EPHA3	6491.0
POLR2A	6488.0
RPL6	6436.0
ZNF638	6416.0
PSENEN	6370.0
PCSK6	6352.0
PTPN11	6327.0
PSMB5	6325.0
LCE2B	6274.0
POLR2G	6258.0
ACTR2	6235.0
SCN3B	6233.0
LHX2	6203.0
AJUBA	6170.0
ITGA1	6163.0
PRSS8	6161.0
CTCF	6152.0
HJV	6117.0
KRTAP6-2	6091.0
DMRT1	6088.0
MYL6	6061.0
YAP1	6059.0
PIK3R3	6057.0
ACTG1	6055.0
SPTBN2	6051.0
SPTA1	6050.0
HOXB4	6046.0
H2BC11	6041.0
LCE6A	6033.0
LPL	6029.0
UPF2	6003.0
RHOA	5999.0
DOK1	5968.0
DLG4	5962.0
RBM8A	5942.0
EPHA10	5920.0
SPTBN4	5916.0
MED18	5913.0
MAPK7	5876.0
KLK8	5832.0
MAFB	5826.0
SEMA4D	5812.0
RPS27L	5802.0
KRT7	5796.0
THRAP3	5777.0
DPYSL4	5763.0
HSPA8	5756.0
RPL5	5746.0
MED21	5726.0
SCN11A	5714.0
LCE4A	5668.0
DPYSL2	5617.0
CNTN2	5591.0
PSMD11	5530.0
FAM120B	5523.0
RPL36	5497.0
PSEN1	5493.0
MMP2	5487.0
RPS18	5479.0
KRTAP2-4	5475.0
H4C6	5474.0
POLR2C	5449.0
TUBA8	5447.0
RPL12	5445.0
PRKACA	5434.0
TGS1	5401.0
CACNA1G	5340.0
IRS2	5337.0
PAX6	5333.0
WNT1	5283.0
EPHA4	5268.0
ZNF467	5255.0
NANOG	5248.0
ARPC4	5246.0
NCBP2	5241.0
HELZ2	5239.0
H4C5	5237.0
BMP4	5234.0
MSI1	5223.0
DNM1	5204.0
KRTAP1-5	5157.0
LCE1E	5153.0
ONECUT3	5152.0
RELN	5138.0
DPYSL5	5137.0
HNF1A	5130.0
PAXIP1	5114.0
SEMA6D	5106.0
PPARA	5081.0
FGF10	5079.0
POLR2I	5052.0
RPL38	5039.0
CNOT9	4978.0
SLC2A4	4918.0
H3-3B	4910.0
CACNA1S	4906.0
RPL13A	4893.5
DOK6	4868.0
H4C1	4857.0
KRT77	4856.0
SEM1	4832.0
PSME1	4820.0
MYH10	4805.0
ERBB2	4769.0
CACNB1	4696.0
RPS8	4682.0
PSMB8	4635.0
CDH1	4631.0
EPHA1	4626.0
KRTAP9-6	4621.0
RPS15A	4574.0
KRTAP12-1	4549.0
H2BC17	4528.0
DNM2	4508.0
RPS20	4493.0
ABLIM3	4428.0
MAP2K1	4420.0
GRB2	4417.0
ARHGAP35	4411.0
NTN1	4374.0
TRPC6	4362.0
FARP2	4359.0
CACNB3	4349.0
NCK1	4325.0
RPL35A	4324.0
CDH4	4317.0
WWTR1	4268.0
HSP90AA1	4261.0
NRP2	4258.0
EPHB4	4246.0
EGFR	4196.0
SHC1	4171.0
DSG2	4162.0
ETF1	4159.0
UNC5D	4151.0
TCHH	4095.0
KRTAP2-2	4079.0
COL9A3	4071.0
HOXB3	4065.0
PKP1	4044.0
PLXNA4	4039.0
EPHA7	4032.0
SRGAP1	4003.0
LEFTY2	3951.0
SEMA6A	3909.0
RNPS1	3907.0
ITGA5	3882.0
SHH	3880.0
LHX4	3875.0
RPS25	3868.0
HOXC4	3865.0
CACNB4	3855.0
MED13	3816.0
UPF3A	3812.0
PI3	3788.0
KLK5	3742.0
GSC	3695.0
WT1	3693.0
PIK3CA	3688.0
UBC	3678.0
WASL	3648.0
WNT4	3640.0
MED17	3600.0
SOX10	3596.0
PPP3CB	3538.0
H4C13	3529.0
H2BC21	3526.0
WDR5	3507.0
NR6A1	3496.0
RPL41	3483.0
HOXB1	3461.0
AKT2	3403.0
CER1	3385.0
NRP1	3365.0
BOC	3352.0
PLXNA2	3324.0
RPL18A	3298.0
H2BC15	3284.0
RPL23	3249.0
MAML1	3242.0
CLTA	3232.0
MEF2D	3203.0
H2AC7	3201.5
H2BC7	3201.5
DKK1	3134.0
NUMB	3088.0
EZR	3082.0
POLR2K	3074.0
FLI1	3067.0
PAK2	3046.0
HNF4G	3042.0
PIK3R2	3041.0
PLIN1	3040.0
PIP5K1C	3038.0
LIMK1	3019.0
TUBA4B	3017.0
KRTAP6-1	3016.0
KRT17	3004.0
KRT84	3003.0
KLF5	2994.0
CEBPA	2961.0
SPTAN1	2944.0
ARPC1A	2942.0
TBX6	2930.0
HSP90AB1	2921.0
MYH9	2916.0
ARHGAP39	2913.0
ITGAV	2902.0
TEAD4	2881.0
UTRN	2854.0
KCNQ2	2849.0
MEF2B	2845.0
VASP	2843.0
GPC1	2842.0
PSMA6	2818.0
SDCBP	2813.0
PRKCA	2793.0
PKP3	2787.0
SREBF2	2770.0
SCN4B	2757.0
H4C3	2755.0
CSNK2A2	2708.0
GFRA3	2707.0
YY1	2687.0
KRT73	2667.0
H2BC5	2649.0
PIAS2	2646.0
PFN2	2642.0
EIF4G1	2605.0
CNOT6	2587.0
ROBO3	2575.0
PTPRC	2570.0
MED6	2492.0
KRTAP4-3	2490.0
GATA4	2489.0
SH3GL2	2478.0
POLR2B	2415.0
ZNF335	2356.0
POLR2F	2354.0
MEIS1	2337.0
ACTB	2300.0
EPHB3	2280.0
AGRN	2259.0
RRAS	2258.0
SCN9A	2244.0
KRTAP19-3	2233.0
LHX3	2229.0
RARB	2200.0
KRTAP19-8	2099.0
RPL17	2047.0
DAG1	2041.0
MYB	2037.0
COL3A1	2031.0
SMAD3	2022.0
CTNNA1	2011.0
GRB7	2007.0
NCOR1	2003.0
H2AZ2	1985.0
CLTCL1	1983.0
PSMD5	1955.0
DAND5	1944.0
PSMC2	1937.0
SMARCD3	1912.0
RPL23A	1900.0
PSMB9	1892.0
CLASP1	1870.0
PSMD14	1828.0
KRT24	1796.0
NEO1	1784.0
H2AC6	1742.0
CDK8	1724.0
DLL3	1720.0
PTK2	1701.0
MEF2A	1698.0
ARHGEF7	1697.0
MED19	1690.0
MYL12A	1686.0
FRS2	1660.0
RPS6KA5	1642.0
GFI1	1603.0
PSMD2	1596.0
RBBP4	1591.0
PPARG	1586.0
EPAS1	1584.0
RPS7	1574.0
RPS28	1519.0
TSC22D1	1511.0
SCN5A	1509.0
GSK3B	1479.0
PRKAR2A	1477.0
COL6A3	1464.0
VAV2	1462.0
LELP1	1404.0
CRMP1	1394.0
TUBB3	1374.0
KRT5	1330.0
FOXO1	1323.0
TUBA1C	1264.0
EPHA8	1242.0
CELA2A	1140.0
TRPC3	1116.0
GAP43	1096.0
PSMB1	1087.0
CTNNA2	1083.0
ADAM22	1080.0
SNW1	1067.0
SEMA3E	1051.0
CDK2	982.0
LCE3B	966.0
RARA	941.0
HDAC3	930.0
MED23	913.0
RPL10L	887.0
KRT83	860.0
NFKB1	848.0
FGFR1	835.0
PRNP	827.0
ARPC2	812.0
MAG	789.0
SPTBN1	767.0
KRTAP29-1	753.0
SIAH1	722.0
RPL21	717.0
NGEF	699.0
PSMB4	682.0
ADGRG6	662.0
UNC5C	654.0
SRC	626.0
LYPLA2	606.0
CDK5	570.0
CEBPD	563.0
RELA	558.0
ST14	540.0
EED	535.0
KRTAP5-7	534.0
PIK3R1	517.0
ADGRV1	506.0
SLIT2	497.0
CAP1	486.0
TRIM33	450.0
ARTN	406.0
PSMB7	389.0
PRX	364.0
SPTB	269.0
CACNG2	263.0
CSNK2A1	246.0
KCNQ3	222.0
TBL1XR1	188.0
HHEX	128.0
EBF1	118.0
MED20	92.0
NELL2	86.0
ABL2	76.0
OCLN	46.0
EFNB2	24.0
RPL22	19.0
ABLIM2	8.0
NAB1	2.0
COL9A2	-27.0
KRTAP10-2	-44.0
GAB1	-61.0
RPL36AL	-101.5
RPL24	-132.0
ROBO1	-136.0
MED7	-145.0
ANK1	-146.0
APH1A	-147.0
LIPN	-155.0
DSCAML1	-179.0
POLR2E	-304.0
VAV3	-314.0
PSMD1	-344.0
PMP22	-352.0
KRT79	-369.0
EGR2	-379.0
GFRA2	-447.0
RBPJ	-464.0
GRIN2B	-473.0
JUP	-494.0
KRTAP5-5	-533.0
COL9A1	-555.0
APH1B	-585.0
AP2A1	-596.0
SCN8A	-619.0
PSMB11	-633.0
SCN2B	-638.0
CASP14	-661.0
FOXP1	-674.0
MYH11	-709.0
IHH	-718.0
HIF3A	-719.0
RPL30	-725.0
RHOB	-743.0
EFNB3	-748.0
PTPRA	-749.0
PTGDS	-755.0
MYO9B	-791.0
CEBPE	-801.0
PBX1	-819.0
LEP	-848.0
CHD9	-854.0
DAB1	-865.0
COL4A1	-866.0
ANK3	-870.0
PAX4	-873.0
RPL34	-891.0
KRT36	-895.0
KRT10	-908.0
NRAS	-916.0
GRB10	-953.0
CACNA1H	-964.0
FYN	-1025.0
PSMA3	-1034.0
CACNA1C	-1042.0
KRT25	-1104.0
KAZN	-1135.0
ZSCAN10	-1159.0
MED9	-1212.0
RPS19	-1286.0
DPYSL3	-1293.0
NFASC	-1294.0
CDON	-1295.0
ZFPM2	-1311.0
KLK12	-1318.0
MET	-1327.0
ITGA2	-1351.0
SRGAP3	-1445.0
COL5A1	-1453.0
RPS27	-1469.0
ELOC	-1484.0
ABL1	-1504.0
ROCK1	-1528.0
DNM3	-1541.0
CACNG8	-1626.0
PLXND1	-1631.0
SREBF1	-1635.0
H3C1	-1648.0
RPL37A	-1652.0
MED30	-1658.0
NTN4	-1687.0
MAML2	-1723.0
KRTAP10-4	-1740.0
NCK2	-1789.0
ARHGEF11	-1792.0
SOS2	-1856.0
MAML3	-1866.0
RPL29	-1880.0
CNTN1	-1882.0
KRT37	-1898.0
TUBB4A	-1926.0
PSMC6	-1967.0
LIMK2	-1997.0
ITSN1	-2015.0
PSMD4	-2016.0
SCN10A	-2018.0
KRT40	-2094.0
MEF2C	-2129.0
POLR2D	-2136.0
MYH14	-2151.0
TRPC7	-2180.0
SMARCA4	-2181.0
MAP2K2	-2192.0
DSP	-2194.0
ASH2L	-2199.0
FURIN	-2200.0
KRTAP11-1	-2211.0
MAFA	-2218.0
MYO10	-2252.0
PLXNA1	-2271.0
PSMD3	-2284.0
CHL1	-2301.0
ADAM10	-2331.0
RPS6KA2	-2353.0
TUBB2A	-2356.0
TRIO	-2375.0
SCN2A	-2392.0
DLG1	-2409.0
TFDP1	-2414.0
NRCAM	-2431.0
DOCK1	-2435.0
NCAM1	-2460.0
INS	-2478.0
CREB1	-2546.0
LAMB1	-2552.0
PSMD6	-2567.0
RPS2	-2570.0
CAPN1	-2590.0
LIPJ	-2597.0
FOXO3	-2607.0
KRAS	-2609.0
NCAN	-2640.0
RPS29	-2664.0
DSG3	-2675.0
MED24	-2691.0
CTNNB1	-2732.0
CCNC	-2734.0
PSMA7	-2741.0
TUBA4A	-2757.0
FGF2	-2778.0
H2BC6	-2787.0
H3C11	-2806.0
AP2A2	-2814.0
RPL4	-2829.0
PKP4	-2851.0
EFNA2	-2860.0
SEMA4A	-2875.0
ABLIM1	-2929.0
CD72	-2931.0
KRTAP3-1	-2952.0
POU3F2	-2966.0
COL6A2	-2971.0
H3C4	-2978.0
H2AX	-2988.0
SPI1	-3000.0
RPL37	-3007.0
RPL11	-3010.0
SCD5	-3042.0
PSMF1	-3068.0
NEUROG3	-3072.0
KRT6A	-3073.0
NCSTN	-3121.0
PLXNB1	-3130.0
KRTAP5-1	-3146.0
STX1A	-3161.0
NAB2	-3183.0
H2BC1	-3185.0
CLTC	-3186.0
CLASP2	-3191.0
DEK	-3200.0
TGM5	-3213.0
CSTA	-3246.0
CDK19	-3252.0
CACNA1D	-3253.0
TUBA1A	-3265.0
KMT2C	-3280.0
NCOA6	-3313.0
MED27	-3338.0
H2AZ1	-3340.0
KRTAP9-2	-3362.0
KRTAP4-4	-3366.0
PKP2	-3410.0
KRT28	-3411.0
KRTAP19-4	-3418.0
NCOA3	-3444.0
DSCAM	-3476.0
UNC5A	-3495.0
EIF4A3	-3505.0
MAPK8	-3508.0
ZSWIM8	-3510.0
FLRT3	-3549.0
SCN1B	-3552.0
KMT2A	-3568.0
PERP	-3618.0
MBP	-3634.0
MED8	-3653.0
PLXNC1	-3669.0
PDLIM7	-3678.0
PSMB2	-3711.0
H3C6	-3784.0
MED25	-3793.0
CSF3R	-3796.0
ROBO2	-3801.0
KRTAP4-6	-3804.0
NCOA1	-3845.0
TEAD1	-3899.0
ITGB1	-3921.0
KRTAP1-1	-3958.0
KRTAP5-4	-4020.0
HDAC2	-4029.0
CARM1	-4075.0
RPS6KA4	-4078.0
RUNX1	-4106.0
KRTAP13-1	-4115.0
RPS21	-4136.0
TCF3	-4162.0
MYOD1	-4168.0
PSMD12	-4181.0
MED15	-4193.0
H2AJ	-4216.0
MAPK14	-4217.0
H2BC10	-4225.0
COL6A5	-4227.0
PSMD7	-4231.0
SEMA5A	-4243.0
ALCAM	-4244.0
RET	-4257.0
RPL26	-4270.0
DCC	-4278.0
PSPN	-4320.0
PSMC4	-4337.0
PIK3CD	-4365.0
H4C16	-4372.0
SLIT3	-4394.0
CREBBP	-4413.0
GAB2	-4414.0
ARHGEF28	-4423.0
NCOR2	-4442.0
MED31	-4483.0
ACVR2A	-4521.0
AP2B1	-4543.0
ARHGEF12	-4558.0
PRKCQ	-4559.0
COL4A2	-4620.0
KRTAP2-3	-4627.0
RPS3	-4641.0
KRTAP4-8	-4643.0
KRTAP9-4	-4658.0
LCE3A	-4661.0
KLK13	-4684.0
SOS1	-4686.0
UNC5B	-4704.0
EPHB6	-4712.0
PML	-4728.0
AKT3	-4731.0
AMH	-4750.0
BNIP2	-4753.0
KALRN	-4756.0
KRT3	-4767.0
MYL9	-4802.0
LCE1C	-4809.0
LAMA1	-4818.0
UBB	-4879.0
DSC3	-4903.0
ANK2	-4981.0
POU5F1	-4990.0
AP2S1	-5011.0
RPL9	-5020.0
LAMC1	-5031.0
PAK1	-5045.0
HNF4A	-5087.0
HOXD4	-5137.0
CLTB	-5191.0
H4C11	-5213.0
PPARGC1A	-5265.0
CEBPB	-5278.0
CDC42	-5289.0
FES	-5341.0
TCF12	-5372.0
GSPT1	-5383.0
SPRR2D	-5392.0
TGFB1	-5394.0
KRT27	-5418.0
SPRR1A	-5437.0
ITGA9	-5548.0
KRT20	-5562.0
KRT6C	-5587.0
SLC2A2	-5595.0
SCN4A	-5609.0
SMAD2	-5636.0
MED26	-5637.0
CD36	-5640.0
YES1	-5778.0
TUBA3E	-5785.0
CDH2	-5793.0
NODAL	-5813.0
PAK5	-5826.0
KRTAP22-1	-5834.0
KRT85	-5843.0
LAMA2	-5863.0
MAGOHB	-5870.0
PSMA1	-5911.0
KRTAP20-2	-5945.0
KRT6B	-5999.0
AKAP5	-6009.0
KRTAP26-1	-6046.0
RND1	-6095.0
NOTCH1	-6124.0
ARPC1B	-6148.0
LYN	-6155.0
SPRR2G	-6156.0
RDX	-6288.0
E2F1	-6335.0
EZH2	-6349.0
TCF4	-6363.0
KRT86	-6372.0
H4C4	-6381.0
RPS6KA1	-6399.0
TRPC4	-6414.0
KRTAP9-1	-6443.0
KRT13	-6461.0
TFDP2	-6465.0
RPL39L	-6470.0
SPTBN5	-6507.0
RXRA	-6528.0
MYF5	-6532.0
EP300	-6560.0
STAT3	-6570.0
KRTAP3-2	-6606.0
PRKACB	-6617.0
RHOC	-6627.0
EPHA6	-6670.0
ADAM23	-6692.0
KRTAP5-3	-6701.0
PIK3CB	-6726.0
KRTAP13-3	-6728.0
KRTAP1-3	-6773.0
TUBB8	-6824.0
KRTAP3-3	-6845.5
DPPA4	-6910.0
KRTAP4-5	-6924.0
H2BC14	-6929.0
MAP2K6	-7001.0
KRTAP15-1	-7018.0
FABP4	-7021.0
SCN1A	-7038.0
KRT76	-7040.0
MYOG	-7045.0
LGI4	-7093.0
GDF1	-7108.0
KRTAP23-1	-7119.0
KRTAP4-1	-7137.0
RPS24	-7143.0
KRT9	-7165.0
DSG1	-7186.0
NCOA2	-7206.0
SCN3A	-7210.0
AGAP2	-7221.0
PSMC5	-7244.0
H2AC14	-7300.0
NRTN	-7325.0
TUBAL3	-7341.0
KRTAP21-2	-7345.0
SCN7A	-7364.0
ROCK2	-7392.0
MYF6	-7420.0
KRTAP12-2	-7493.0
KRTAP1-4	-7498.0
MED13L	-7499.0
COL5A3	-7533.0
KRTAP10-3	-7590.0
SUZ12	-7600.0
MMP9	-7604.0
H3C3	-7636.0
IAPP	-7653.0
KRTAP5-9	-7745.0
TBPL2	-7865.0
NR5A1	-7888.0
SPINK6	-7939.0
MYL12B	-7981.0
KRTAP25-1	-8010.0
LEFTY1	-8017.0
MED16	-8018.0
SEMA3A	-8026.0
KAT2A	-8049.0
TREM2	-8054.0
KRTAP19-5	-8055.0
PAK4	-8079.0
SPINK5	-8083.0
H2BC3	-8138.0
PSMA8	-8172.0
KRTAP8-1	-8187.0
COL6A6	-8198.0
HOXB2	-8217.0
KRTAP19-6	-8225.0
TUBA3C	-8246.0
LCE3D	-8280.0
KRTAP4-2	-8325.0
LIPK	-8337.0
HOXA4	-8388.0
ELOB	-8397.0
KRT72	-8400.0
DSC1	-8426.0
KIF4B	-8455.0
KRTAP24-1	-8470.0
KRTAP19-7	-8494.0
EVPL	-8512.0
CNTN6	-8513.0
H3C8	-8543.0
KRTAP10-8	-8616.0
KRTAP19-2	-8653.0
SPRR2A	-8692.0
KRT26	-8704.0
SPRR2F	-8740.0
KRT12	-8761.0
DSG4	-8809.0
KRT75	-8821.0
KRTAP13-2	-8891.0
TYROBP	-8928.0
KRTAP5-6	-8989.0
KRTAP10-11	-9019.0
KRTAP10-9	-9106.0
SPRR2E	-9145.0
KRT33B	-9151.0

---

REACTOME_CELLULAR_RESPONSES_TO_STIMULI

REACTOME_CELLULAR_RESPONSES_TO_STIMULI

	1314
set	REACTOME_CELLULAR_RESPONSES_TO_STIMULI
setSize	779
pANOVA	0.00329
s.dist	0.0619
p.adjustANOVA	0.154

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TUBA3D	12586
H2BC26	12438
RPS3A	12354
RPL35	12299
CREB3	12254
TINF2	12172
POM121C	12168
H3C2	12075
UBA52	12048
MIR24-1	12004
RPL7A	11993
COX6B1	11987
TUBB1	11981
ANAPC1	11979
CRYAB	11950
MT1X	11927
CDKN2B	11922
HSPB2	11904
RPS10	11901
EGLN2	11891

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TUBA3D	12586.0
H2BC26	12438.0
RPS3A	12354.0
RPL35	12299.0
CREB3	12254.0
TINF2	12172.0
POM121C	12168.0
H3C2	12075.0
UBA52	12048.0
MIR24-1	12004.0
RPL7A	11993.0
COX6B1	11987.0
TUBB1	11981.0
ANAPC1	11979.0
CRYAB	11950.0
MT1X	11927.0
CDKN2B	11922.0
HSPB2	11904.0
RPS10	11901.0
EGLN2	11891.0
E2F2	11869.0
H2AC18	11842.5
H2AC19	11842.5
CDKN2C	11797.0
PSMD8	11740.0
CRTC2	11727.0
GCN1	11673.0
HSPB1	11649.0
ACTR1A	11647.0
KHSRP	11562.0
PSMB6	11526.0
FKBP14	11378.0
RBX1	11330.0
PSME2	11317.0
MT1G	11293.0
TLN1	11256.0
HSPB8	11230.0
MT1A	11115.0
ID1	10966.0
RPL8	10951.0
H4C12	10931.0
RPS14	10917.0
RPL13	10880.0
RRAGD	10877.0
RPS16	10867.0
NCF2	10829.0
PSMD13	10801.0
NDUFA4	10777.0
ERN1	10775.0
POM121	10729.0
HSPA12A	10720.0
PRDX6	10637.0
HSPA1B	10631.0
TUBB4B	10619.0
TUBB2B	10586.0
JUN	10584.0
CCNE2	10522.0
RPLP0	10491.0
RPS12	10471.0
RPLP1	10423.0
PSMA2	10419.0
WTIP	10406.0
HSBP1	10404.0
RPSA	10389.0
RPLP2	10388.0
AGO4	10384.0
MAPK3	10376.0
TPP1	10359.0
MAP2K3	10332.0
ERF	10317.0
CITED2	10249.0
H4C8	10222.0
AGO1	10202.0
H4C9	10176.0
PPP2R5B	10174.0
CSNK2B	10153.0
MAFG	10150.0
PRDX3	10144.0
NUP155	10125.0
IDH1	10119.0
CDKN1A	10113.0
COX14	10054.0
EPO	10044.0
RPS9	10000.0
COX4I1	9976.0
H2BC8	9970.0
TLR4	9946.0
BAG5	9935.0
ACD	9928.5
RPL27	9921.0
CREB3L1	9901.0
TACO1	9873.0
CDK4	9809.0
ANAPC10	9802.0
CAMK2A	9796.0
KLHDC3	9705.0
CRYBA4	9692.0
DIS3	9687.0
WFS1	9671.0
CRTC3	9649.0
LMNB1	9639.0
H3C12	9636.0
CCNA1	9633.0
H2BC13	9599.0
ERO1A	9598.0
RPL19	9586.0
CREB3L4	9557.0
RPL10A	9510.0
PSMC3	9473.0
ATP6V1C1	9459.0
RPL28	9439.0
PPP1R15A	9424.0
HSPA5	9422.0
RPS26	9398.0
MAPK1	9390.0
COX7A2L	9342.0
NCF4	9337.0
RPL3L	9335.0
PSMC1	9330.0
DYNLL1	9329.0
RPL15	9318.0
ITFG2	9304.0
DYNLL2	9301.0
PSMA5	9295.0
HSPH1	9292.0
TUBA1B	9290.0
SEH1L	9275.0
HERPUD1	9261.0
RPS5	9174.0
RPL31	9139.0
AKT1	9135.0
HSPA2	9111.0
MT2A	9080.0
CAPZA2	9030.0
ATOX1	9009.0
SIN3B	8990.0
MIOS	8980.0
GOSR2	8967.0
H4C2	8932.0
COX8A	8919.0
GFPT1	8865.0
LAMTOR5	8846.0
APOA1	8843.0
FABP1	8812.0
PHC1	8772.0
TUBB6	8725.0
NR1D1	8711.0
GCLM	8671.0
EXOSC8	8664.0
HMOX2	8656.0
SERP1	8654.0
TKT	8631.0
MYC	8608.0
ASNS	8596.0
RB1	8587.0
UBXN7	8533.0
RPS23	8529.0
MED1	8525.0
SEC13	8518.0
UBE2D3	8435.0
MT4	8434.0
COX5B	8389.0
NPRL2	8363.0
CDKN1B	8330.0
RPS15	8328.0
HDGF	8326.0
EIF2S1	8314.0
NPAS2	8312.0
H2BC9	8277.5
H3C7	8277.5
NUP43	8265.0
LRPPRC	8231.0
FAU	8229.0
HIGD1A	8216.0
ATP6V1B1	8164.0
RPL7	8155.0
RPS13	8147.0
COX5A	8137.0
RRAGC	8124.0
MINK1	8091.0
MAPKAPK5	8035.0
BAG4	7949.0
CCL2	7934.0
H2BC12	7877.0
RORA	7842.0
PSME4	7823.0
TP53	7787.0
RPL26L1	7785.0
H2AC20	7782.0
CCAR2	7761.0
PRKCD	7759.0
RPA1	7730.0
EXOSC5	7685.0
CUL2	7630.0
ATP6V1G2	7612.0
STIP1	7593.0
SLC46A1	7534.0
RAE1	7531.0
ANAPC16	7528.0
SSR1	7505.0
IMPACT	7456.0
FOS	7444.0
DNAJA1	7420.0
H3-3A	7400.0
RPS11	7339.0
PSMB10	7323.0
PSMD9	7312.0
HIF1A	7279.0
H1-2	7275.0
RPL22L1	7254.0
RPL14	7148.0
H3C10	7119.0
SURF1	7110.0
KPTN	7104.0
RPS6	7103.0
ANAPC7	7099.0
RPL18	7051.0
RPL32	7038.0
TXN	7032.0
AKT1S1	7023.0
CDC26	6995.0
PSMA4	6990.0
RPL27A	6977.0
YIF1A	6973.0
GSR	6953.0
PSMB3	6907.0
CA9	6897.0
H2BC4	6860.0
ST13	6850.0
RPL3	6848.0
H2AC4	6819.0
BLVRB	6782.0
RPS27A	6760.0
SOD1	6759.0
MAPK11	6753.0
VCP	6711.0
RRAGA	6632.0
H2AC8	6620.0
TERF2	6529.0
TERF2IP	6509.0
PSME3	6499.0
XBP1	6468.0
RPL6	6436.0
MT3	6379.0
PSMB5	6325.0
ATR	6277.0
NBN	6237.0
NFYA	6231.0
ATP6V1E1	6184.0
AJUBA	6170.0
VEGFA	6162.0
TXNIP	6157.0
VENTX	6075.0
MLST8	6060.0
H2BC11	6041.0
DYNC1LI2	5997.0
MT1B	5949.0
MAPK7	5876.0
TATDN2	5851.0
RPS27L	5802.0
EDEM1	5789.0
HSPA8	5756.0
RPL5	5746.0
HIRA	5716.0
HSPA13	5711.0
HSF1	5708.0
TNRC6A	5686.0
EGLN3	5654.0
KEAP1	5645.0
GPX2	5627.0
FKBP4	5579.0
DYNC1I2	5565.0
SP1	5543.0
PSMD11	5530.0
PTGES3	5515.0
RPL36	5497.0
RPS18	5479.0
H4C6	5474.0
TUBA8	5447.0
RPL12	5445.0
BAG1	5428.0
TGS1	5401.0
FNIP1	5365.0
DEDD2	5319.0
GSTA3	5311.0
HELZ2	5239.0
H4C5	5237.0
MDM2	5154.0
CREB3L3	5148.0
CAMK2G	5094.0
PPARA	5081.0
RPL38	5039.0
SRPRB	5027.0
NUP214	4993.0
NR3C2	4956.0
EXTL3	4946.0
POT1	4945.0
H3-3B	4910.0
RPL13A	4893.5
EXOSC7	4885.0
H4C1	4857.0
SEM1	4832.0
PSME1	4820.0
TXN2	4781.0
DNAJB9	4772.0
COX6A1	4760.0
SIN3A	4733.0
DNAJB11	4689.0
RPS8	4682.0
ACADVL	4670.0
PSMB8	4635.0
CCNE1	4633.0
RPS15A	4574.0
ATP6V1D	4573.0
PDIA6	4538.0
H2BC17	4528.0
NFYB	4517.0
RPS20	4493.0
GSK3A	4474.0
DYNC1LI1	4409.0
HBA2	4399.0
CAPZA3	4336.0
RPL35A	4324.0
NOX4	4320.0
EIF2AK4	4279.0
HSP90AA1	4261.0
ANAPC11	4231.0
SRPRA	4218.0
HYOU1	4211.0
DYNC1H1	4197.0
SHC1	4171.0
CDKN2D	4164.0
DCSTAMP	3975.0
NUP133	3960.0
RHEB	3933.0
CHAC1	3930.0
ATP6V1G3	3921.0
RPS25	3868.0
UBE2D1	3827.0
WDR59	3820.0
CRTC1	3817.0
HM13	3803.0
CTDSP2	3802.0
NUP62	3793.0
TNRC6B	3765.0
NPRL3	3756.0
NLRP3	3723.0
TRIB3	3680.0
UBC	3678.0
HIF1AN	3665.0
UBN1	3554.0
ATF5	3552.0
H4C13	3529.0
H2BC21	3526.0
EHMT1	3518.0
UBE2S	3510.0
RPL41	3483.0
HSPA4	3453.0
BAG2	3423.0
AKT2	3403.0
CLEC1B	3391.0
PTK6	3390.0
H1-3	3332.0
SCO1	3308.0
RPL18A	3298.0
H2BC15	3284.0
SYVN1	3277.0
RPL23	3249.0
MEF2D	3203.0
H2AC7	3201.5
H2BC7	3201.5
KDELR3	3118.0
ABCC1	3065.0
APOB	3055.0
TUBA4B	3017.0
HSP90AB1	2921.0
HSPA4L	2871.0
RPS19BP1	2832.0
PSMA6	2818.0
SCO2	2779.0
H4C3	2755.0
HMGA1	2753.0
VHL	2745.0
GPX7	2742.0
SESN2	2737.0
NDC1	2732.0
CSNK2A2	2708.0
SLC38A9	2696.0
ATP6V0E2	2666.0
H2BC5	2649.0
ETS2	2636.0
MTOR	2633.0
TXNRD2	2580.0
CAMK2D	2571.0
GPX1	2471.0
LAMTOR2	2432.0
UBE2D2	2376.0
EEF1A1	2350.0
KAT5	2338.0
NUP37	2220.0
CAPZB	2195.0
MTF1	2172.0
MRPL18	2148.0
HSPA1A	2130.0
SKP1	2126.0
RPL17	2047.0
ATP6V1F	2009.0
NCOR1	2003.0
H2AZ2	1985.0
PSMD5	1955.0
MUL1	1946.0
PSMC2	1937.0
SMARCD3	1912.0
RPL23A	1900.0
PSMB9	1892.0
ACTR10	1839.0
PSMD14	1828.0
NFE2L2	1788.0
MT1F	1782.0
CAMK2B	1772.0
PHC2	1764.0
H2AC6	1742.0
PSMD2	1596.0
RBBP4	1591.0
EPAS1	1584.0
RPS7	1574.0
RPS28	1519.0
TALDO1	1510.0
GSK3B	1479.0
EHMT2	1444.0
ATF4	1438.0
TUBB3	1374.0
H3-4	1343.0
LAMTOR4	1310.0
KICS2	1277.0
IL1A	1269.0
MRE11	1265.0
TUBA1C	1264.0
DCTN6	1255.0
EP400	1240.0
NUDT2	1201.0
BMAL1	1179.0
NUP42	1173.0
IGFBP7	1159.0
HSPA1L	1094.0
PSMB1	1087.0
NR3C1	1013.0
RAI1	1011.0
CDK2	982.0
HDAC3	930.0
RPL10L	887.0
AAAS	854.0
NFKB1	848.0
EIF2AK1	766.0
MT1H	739.0
RPL21	717.0
PSMB4	682.0
BRCA1	650.0
STAP2	641.0
EXOSC2	613.0
NUP107	598.0
EXOSC6	596.0
NUP35	590.0
CREB3L2	561.0
RELA	558.0
EED	535.0
MOV10	519.0
CDKN2A	501.0
DEPDC5	491.0
HBB	422.0
PSMB7	389.0
UFD1	361.0
BAG3	347.0
AGO3	328.0
MBTPS1	321.0
RPA2	316.0
NFYC	280.0
CSNK2A1	246.0
TBL1XR1	188.0
USP46	135.0
CCS	88.0
MAPKAPK2	69.0
KDM6B	35.0
ATF3	25.0
RPL22	19.0
IGFBP1	14.0
ATP6V0D2	-20.0
NUP88	-30.0
PRDX2	-71.0
FLCN	-94.0
RPL36AL	-101.5
NUP93	-114.0
DCTN1	-116.0
RPL24	-132.0
NUP54	-134.0
LAMTOR1	-181.0
DNAJC7	-272.0
LIMD1	-311.0
ETS1	-323.0
PSMD1	-344.0
DNAJA4	-442.0
ATP6V0D1	-460.0
NUP210	-490.0
GPX8	-512.0
ATF6	-525.0
HSPA9	-538.0
DNAJA2	-566.0
PSMB11	-633.0
SOD2	-716.0
HIF3A	-719.0
RPL30	-725.0
CBX4	-773.0
HSPA12B	-799.0
PLA2G4B	-807.0
CABIN1	-822.0
NQO1	-842.0
FKBP5	-852.0
CHD9	-854.0
MYDGF	-867.0
MAP4K4	-884.0
RPL34	-891.0
PRDX5	-918.0
E2F3	-921.0
WDR24	-945.0
DPP3	-946.0
GRB10	-953.0
MT1M	-976.0
PDIA5	-1006.0
CASTOR1	-1013.0
PSMA3	-1034.0
CDK6	-1083.0
DCTN3	-1118.0
NUP160	-1161.0
MAP2K4	-1209.0
CAPZA1	-1211.0
ATP6V1C2	-1221.0
ANAPC2	-1227.0
RPS19	-1286.0
ATP6V0C	-1320.0
ATP6V1B2	-1330.0
DNAJB1	-1427.0
RNF2	-1431.0
RPTOR	-1437.0
RPS27	-1469.0
CDC16	-1479.0
ELOC	-1484.0
PREB	-1495.0
LY96	-1564.0
H3C1	-1648.0
RPL37A	-1652.0
COX20	-1699.0
DCTN5	-1754.0
H1-4	-1760.0
NOX5	-1774.0
CXXC1	-1796.0
H1-5	-1875.0
RPL29	-1880.0
SEC31A	-1912.0
TUBB4A	-1926.0
PSMC6	-1967.0
NUP85	-1979.0
SRXN1	-2006.0
PSMD4	-2016.0
COX7C	-2025.0
ARFGAP1	-2066.0
SESN1	-2067.0
EXOSC4	-2086.0
MEF2C	-2129.0
SERPINH1	-2142.0
MAP3K5	-2231.0
PSMD3	-2284.0
RPA3	-2347.0
RPS6KA2	-2353.0
TUBB2A	-2356.0
ATP6V1H	-2408.0
TERF1	-2412.0
TFDP1	-2414.0
CREB1	-2546.0
PSMD6	-2567.0
RPS2	-2570.0
NUP153	-2599.0
CYCS	-2645.0
HBA1	-2660.0
RPS29	-2664.0
EXOSC3	-2729.0
PSMA7	-2741.0
GCLC	-2755.0
TUBA4A	-2757.0
MAP2K7	-2774.0
DYNC1I1	-2779.0
H2BC6	-2787.0
UBE2E1	-2788.0
H3C11	-2806.0
ATP6V0B	-2813.0
RPL4	-2829.0
ATM	-2924.0
EIF2AK3	-2959.0
NUP98	-2974.0
H3C4	-2978.0
H2AX	-2988.0
DCTN2	-2996.0
RPL37	-3007.0
RPL11	-3010.0
CSRP1	-3046.0
SLC7A11	-3060.0
SQSTM1	-3066.0
PSMF1	-3068.0
NUP50	-3125.0
DNAJC3	-3149.0
TNIK	-3179.0
H2BC1	-3185.0
GPX5	-3212.0
HMGA2	-3217.0
HSPA14	-3242.0
TUBA1A	-3265.0
NCOA6	-3313.0
H2AZ1	-3340.0
GPX3	-3351.0
RING1	-3408.0
CYBA	-3425.0
MAPK8	-3508.0
CUL7	-3573.0
CEBPG	-3612.0
ALB	-3631.0
ATP6V1G1	-3670.0
RANBP2	-3704.0
PSMB2	-3711.0
CUL3	-3712.0
TPR	-3725.0
ATF2	-3745.0
H3C6	-3784.0
BMI1	-3786.0
MDM4	-3819.0
NCOA1	-3845.0
TNFRSF21	-3864.0
ANAPC5	-3872.0
BTRC	-3999.0
SH3BP4	-4024.0
MAPK9	-4072.0
CARM1	-4075.0
ADD1	-4104.0
RPS21	-4136.0
GSTP1	-4156.0
PSMD12	-4181.0
H2AJ	-4216.0
MAPK14	-4217.0
H2BC10	-4225.0
HMOX1	-4226.0
PSMD7	-4231.0
RPL26	-4270.0
CCNA2	-4303.0
PSMC4	-4337.0
H4C16	-4372.0
MAPK10	-4373.0
COX18	-4380.0
FBXL17	-4385.0
CREBBP	-4413.0
NCOR2	-4442.0
DDX11	-4533.0
CDC23	-4597.0
DCTN4	-4604.0
RPS3	-4641.0
NUP205	-4655.0
COX11	-4730.0
AKT3	-4731.0
ARNT	-4757.0
PARN	-4786.0
WIPI1	-4791.0
SNCB	-4808.0
CREBRF	-4815.0
BACH1	-4822.0
TXNRD1	-4823.0
UBE2C	-4848.0
SZT2	-4860.0
RAD50	-4876.0
UBB	-4879.0
PGR	-4893.0
ATP6V1A	-4925.0
EXTL1	-4931.0
EIF2S2	-4933.0
CBX2	-4942.0
YWHAE	-4961.0
TNRC6C	-5013.0
RPL9	-5020.0
EGLN1	-5109.0
PALB2	-5183.0
H4C11	-5213.0
XPO1	-5236.0
PPARGC1A	-5265.0
CEBPB	-5278.0
CLOCK	-5280.0
TRIM21	-5283.0
FZR1	-5322.0
ME1	-5353.0
PGD	-5361.0
CDC27	-5367.0
CALR	-5378.0
H1-0	-5432.0
DNAJB6	-5448.0
CXCL8	-5475.0
PRDX1	-5513.0
SIRT1	-5643.0
BLVRA	-5689.0
ANAPC15	-5701.0
SOD3	-5710.0
TCIRG1	-5743.0
ANAPC4	-5783.0
TUBA3E	-5785.0
PSMA1	-5911.0
CUL1	-6004.0
MAP1LC3B	-6064.0
DCP2	-6099.0
NOTCH1	-6124.0
HSPA6	-6132.0
H1-1	-6253.0
CAT	-6326.0
E2F1	-6335.0
EZH2	-6349.0
MAPKAPK3	-6371.0
NUP188	-6377.0
H4C4	-6381.0
SCMH1	-6397.0
RPS6KA1	-6399.0
HIKESHI	-6453.0
TFDP2	-6465.0
RPL39L	-6470.0
MT1E	-6489.0
NPLOC4	-6499.0
RXRA	-6528.0
EXOSC9	-6550.0
EP300	-6560.0
ASF1A	-6564.0
STAT3	-6570.0
P4HB	-6588.0
LMNA	-6635.0
DDIT3	-6649.0
EXTL2	-6764.0
TUBB8	-6824.0
H2BC14	-6929.0
CBX6	-6979.0
FNIP2	-6986.0
MAP2K6	-7001.0
PHC3	-7127.0
RPS24	-7143.0
NRIP1	-7174.0
MAFK	-7185.0
NCOA2	-7206.0
HSP90B1	-7215.0
PSMC5	-7244.0
H2AC14	-7300.0
TUBAL3	-7341.0
IL6	-7357.0
COX19	-7486.0
LAMTOR3	-7596.0
SUZ12	-7600.0
H3C3	-7636.0
COX6C	-7648.0
CBX8	-7760.0
GML	-7784.0
ZBTB17	-7845.0
SKP2	-7874.0
MIR24-2	-7875.0
BMT2	-7892.0
COX16	-7894.0
DNAJC2	-7913.0
EXOSC1	-7962.0
H2BC3	-8138.0
ATP6V1E2	-8149.0
NUP58	-8164.0
PSMA8	-8172.0
TUBA3C	-8246.0
AQP8	-8282.0
ATP6V0E1	-8365.0
ELOB	-8397.0
IFNB1	-8425.0
GPX6	-8452.0
H3C8	-8543.0
GSTA1	-8814.0
RLN1	-9116.0

---

REACTOME_INFLUENZA_INFECTION

REACTOME_INFLUENZA_INFECTION

	228
set	REACTOME_INFLUENZA_INFECTION
setSize	149
pANOVA	0.00332
s.dist	0.139
p.adjustANOVA	0.154

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS3A	12354
RPL35	12299
POM121C	12168
UBA52	12048
RPL7A	11993
RPS10	11901
RAN	11278
RPL8	10951
RPS14	10917
POLR2H	10916
RPL13	10880
RPS16	10867
POM121	10729
RPLP0	10491
RPS12	10471
RPLP1	10423
RPSA	10389
RPLP2	10388
ISG15	10380
NUP155	10125

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS3A	12354.0
RPL35	12299.0
POM121C	12168.0
UBA52	12048.0
RPL7A	11993.0
RPS10	11901.0
RAN	11278.0
RPL8	10951.0
RPS14	10917.0
POLR2H	10916.0
RPL13	10880.0
RPS16	10867.0
POM121	10729.0
RPLP0	10491.0
RPS12	10471.0
RPLP1	10423.0
RPSA	10389.0
RPLP2	10388.0
ISG15	10380.0
NUP155	10125.0
POLR2J	10004.0
RPS9	10000.0
RPL27	9921.0
RPL19	9586.0
RPL10A	9510.0
RPL28	9439.0
RPS26	9398.0
RPL3L	9335.0
RPL15	9318.0
SEH1L	9275.0
RPS5	9174.0
RPL31	9139.0
RPS23	8529.0
SEC13	8518.0
RPS15	8328.0
NUP43	8265.0
FAU	8229.0
GRSF1	8159.0
RPL7	8155.0
RPS13	8147.0
RPL26L1	7785.0
RAE1	7531.0
POLR2L	7368.0
RPS11	7339.0
RPL22L1	7254.0
RPL14	7148.0
RPS6	7103.0
RPL18	7051.0
RPL32	7038.0
RPL27A	6977.0
RPL3	6848.0
RPS27A	6760.0
POLR2A	6488.0
RPL6	6436.0
POLR2G	6258.0
RPS27L	5802.0
RPL5	5746.0
RPL36	5497.0
RPS18	5479.0
POLR2C	5449.0
RPL12	5445.0
POLR2I	5052.0
RPL38	5039.0
NUP214	4993.0
RPL13A	4893.5
RPS8	4682.0
RPS15A	4574.0
RPS20	4493.0
KPNA2	4433.0
RPL35A	4324.0
HSP90AA1	4261.0
NUP133	3960.0
RPS25	3868.0
NUP62	3793.0
RPL41	3483.0
RPL18A	3298.0
RPL23	3249.0
CLTA	3232.0
POLR2K	3074.0
NDC1	2732.0
CPSF4	2720.0
POLR2B	2415.0
POLR2F	2354.0
NUP37	2220.0
HSPA1A	2130.0
RPL17	2047.0
RPL23A	1900.0
GTF2F2	1694.0
RPS7	1574.0
RPS28	1519.0
NUP42	1173.0
KPNB1	1148.0
KPNA4	1001.0
RPL10L	887.0
AAAS	854.0
RPL21	717.0
KPNA3	630.0
NUP107	598.0
NUP35	590.0
RPL22	19.0
NUP88	-30.0
RPL36AL	-101.5
NUP93	-114.0
RPL24	-132.0
NUP54	-134.0
POLR2E	-304.0
NUP210	-490.0
RPL30	-725.0
RPL34	-891.0
NUP160	-1161.0
KPNA1	-1274.0
RPS19	-1286.0
RPS27	-1469.0
RPL37A	-1652.0
RPL29	-1880.0
NUP85	-1979.0
POLR2D	-2136.0
PARP1	-2470.0
PABPN1	-2534.0
RPS2	-2570.0
NUP153	-2599.0
RPS29	-2664.0
RPL4	-2829.0
NUP98	-2974.0
RPL37	-3007.0
RPL11	-3010.0
NUP50	-3125.0
DNAJC3	-3149.0
CLTC	-3186.0
EIF2AK2	-3660.0
RANBP2	-3704.0
TPR	-3725.0
GTF2F1	-3886.0
RPS21	-4136.0
RPL26	-4270.0
RPS3	-4641.0
NUP205	-4655.0
RPL9	-5020.0
XPO1	-5236.0
CALR	-5378.0
TGFB1	-5394.0
KPNA5	-5601.0
NUP188	-6377.0
RPL39L	-6470.0
IPO5	-6497.0
CANX	-6875.0
RPS24	-7143.0
NUP58	-8164.0
KPNA7	-8596.0

---

REACTOME_PI_3K_CASCADE_FGFR1

REACTOME_PI_3K_CASCADE_FGFR1

	939
set	REACTOME_PI_3K_CASCADE_FGFR1
setSize	21
pANOVA	0.00338
s.dist	0.369
p.adjustANOVA	0.154

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FGF20	11659
FGF5	10861
FGF22	10147
FGF17	9443
FGF4	8965
FGF9	8830
FGF8	8081
FGF3	7841
KL	7480
FGF6	7242
FGF1	6404
PTPN11	6327
FGF23	5385
FGF10	5079
GRB2	4417
PIK3CA	3688
FRS2	1660
FGFR1	835
PIK3R1	517
GAB1	-61

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FGF20	11659
FGF5	10861
FGF22	10147
FGF17	9443
FGF4	8965
FGF9	8830
FGF8	8081
FGF3	7841
KL	7480
FGF6	7242
FGF1	6404
PTPN11	6327
FGF23	5385
FGF10	5079
GRB2	4417
PIK3CA	3688
FRS2	1660
FGFR1	835
PIK3R1	517
GAB1	-61
FGF2	-2778

---

REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY

REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY

	1591
set	REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY
setSize	33
pANOVA	0.00343
s.dist	0.294
p.adjustANOVA	0.154

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS3A	12354
RPS10	11901
RPS14	10917
RPS16	10867
RPS12	10471
RPSA	10389
RPS9	10000
RPS26	9398
RPS5	9174
RPS23	8529
RPS15	8328
FAU	8229
RPS13	8147
RPS11	7339
RPS6	7103
RPS27A	6760
RPS27L	5802
RPS18	5479
RPS8	4682
RPS15A	4574

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS3A	12354
RPS10	11901
RPS14	10917
RPS16	10867
RPS12	10471
RPSA	10389
RPS9	10000
RPS26	9398
RPS5	9174
RPS23	8529
RPS15	8328
FAU	8229
RPS13	8147
RPS11	7339
RPS6	7103
RPS27A	6760
RPS27L	5802
RPS18	5479
RPS8	4682
RPS15A	4574
RPS20	4493
HNRNPA1	4099
RPS25	3868
EEF1A1	2350
RPS7	1574
RPS28	1519
RPS19	-1286
RPS27	-1469
RPS2	-2570
RPS29	-2664
RPS21	-4136
RPS3	-4641
RPS24	-7143

---

REACTOME_NEGATIVE_REGULATION_OF_FGFR3_SIGNALING

REACTOME_NEGATIVE_REGULATION_OF_FGFR3_SIGNALING

	954
set	REACTOME_NEGATIVE_REGULATION_OF_FGFR3_SIGNALING
setSize	28
pANOVA	0.00359
s.dist	0.318
p.adjustANOVA	0.154

Top enriched genes

Top 20 genes

GeneID	Gene Rank
UBA52	12048
FGF20	11659
PPP2CB	11602
FGF5	10861
MAPK3	10376
FGF17	9443
MAPK1	9390
FGF4	8965
FGF9	8830
FGF8	8081
FGFR3	7405
PPP2R1A	7026
PPP2CA	6858
RPS27A	6760
FGF1	6404
PTPN11	6327
FGF23	5385
SPRY2	4430
GRB2	4417
BRAF	4204

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
UBA52	12048
FGF20	11659
PPP2CB	11602
FGF5	10861
MAPK3	10376
FGF17	9443
MAPK1	9390
FGF4	8965
FGF9	8830
FGF8	8081
FGFR3	7405
PPP2R1A	7026
PPP2CA	6858
RPS27A	6760
FGF1	6404
PTPN11	6327
FGF23	5385
SPRY2	4430
GRB2	4417
BRAF	4204
UBC	3678
FRS2	1660
SRC	626
CBL	-1592
FGF2	-2778
MKNK1	-3811
UBB	-4879
FGF18	-6573

---

REACTOME_FGFR2_MUTANT_RECEPTOR_ACTIVATION

REACTOME_FGFR2_MUTANT_RECEPTOR_ACTIVATION

	288
set	REACTOME_FGFR2_MUTANT_RECEPTOR_ACTIVATION
setSize	32
pANOVA	0.00361
s.dist	0.297
p.adjustANOVA	0.154

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FGF20	11659
POLR2H	10916
FGF5	10861
FGF22	10147
POLR2J	10004
FGF17	9443
NCBP1	9341
FGF4	8965
FGF9	8830
FGF8	8081
FGF3	7841
FGFR2	7428
POLR2L	7368
FGF6	7242
POLR2A	6488
FGF1	6404
POLR2G	6258
POLR2C	5449
FGF23	5385
NCBP2	5241

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FGF20	11659
POLR2H	10916
FGF5	10861
FGF22	10147
POLR2J	10004
FGF17	9443
NCBP1	9341
FGF4	8965
FGF9	8830
FGF8	8081
FGF3	7841
FGFR2	7428
POLR2L	7368
FGF6	7242
POLR2A	6488
FGF1	6404
POLR2G	6258
POLR2C	5449
FGF23	5385
NCBP2	5241
FGF10	5079
POLR2I	5052
POLR2K	3074
POLR2B	2415
POLR2F	2354
GTF2F2	1694
POLR2E	-304
POLR2D	-2136
FGF2	-2778
GTF2F1	-3886
FGF18	-6573
FGF7	-6850

---

REACTOME_MAPK_FAMILY_SIGNALING_CASCADES

REACTOME_MAPK_FAMILY_SIGNALING_CASCADES

	991
set	REACTOME_MAPK_FAMILY_SIGNALING_CASCADES
setSize	314
pANOVA	0.00366
s.dist	0.0954
p.adjustANOVA	0.154

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MIR34C	12418
RAG1	12275
MIR34B	12103
UBA52	12048
DUSP2	11924
PSMD8	11740
FGF20	11659
HSPB1	11649
DUSP7	11638
PPP2CB	11602
PSMB6	11526
EREG	11436
RBX1	11330
PSME2	11317
TLN1	11256
CDC42EP5	11180
SPRED1	11131
NEFL	10905
PRKACG	10893
FGF5	10861

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MIR34C	12418
RAG1	12275
MIR34B	12103
UBA52	12048
DUSP2	11924
PSMD8	11740
FGF20	11659
HSPB1	11649
DUSP7	11638
PPP2CB	11602
PSMB6	11526
EREG	11436
RBX1	11330
PSME2	11317
TLN1	11256
CDC42EP5	11180
SPRED1	11131
NEFL	10905
PRKACG	10893
FGF5	10861
PPP1CC	10802
PSMD13	10801
LAT	10714
PAQR3	10686
IL6R	10618
JUN	10584
ITGA2B	10549
HRAS	10478
FGA	10456
PSMA2	10419
AGO4	10384
MAPK3	10376
AGO1	10202
PPP2R5B	10174
SHC3	10168
FGF22	10147
GFRA4	9943
FNTB	9911
DUSP5	9883
CAMK2A	9796
CNKSR1	9781
SEPTIN7	9715
FLT3LG	9660
GFRA1	9626
PPP2R5D	9622
PSMC3	9473
FGF17	9443
MAPK1	9390
MRAS	9375
PSMC1	9330
IL2RB	9298
PSMA5	9295
IL2	9156
KSR1	9109
YWHAB	9072
DUSP1	9000
FGF4	8965
IL17RD	8941
FGF9	8830
PDE6D	8667
MYC	8608
FRS3	8566
RASAL3	8504
GRIN1	8502
FGF19	8372
PDGFRA	8304
MAPK12	8274
ITGB3	8268
FGF8	8081
MAPKAPK5	8035
AREG	7916
RAP1B	7895
FGF3	7841
PSME4	7823
FGFR4	7821
KL	7480
FGFR2	7428
CDC42EP2	7418
FGFR3	7405
PDGFB	7346
PSMB10	7323
PSMD9	7312
FGF6	7242
PPP2R1A	7026
PSMA4	6990
RASA1	6976
CCND3	6916
PSMB3	6907
FGB	6905
RAC1	6880
PPP2CA	6858
ABHD17C	6816
RPS27A	6760
GDNF	6723
BCL2L1	6638
SYNGAP1	6569
RANBP9	6549
PSME3	6499
FGF1	6404
KBTBD7	6372
PTPN11	6327
PSMB5	6325
ERBB3	6322
SPRED3	6282
IL6ST	6107
ICMT	6071
ACTG1	6055
SPTBN2	6051
SPTA1	6050
PHB1	6019
DLG4	5962
SPTBN4	5916
NRG2	5860
TNRC6A	5686
HGF	5629
PSMD11	5530
GRIN2D	5500
MMP2	5487
PRKACA	5434
TEK	5410
KLB	5388
FGF23	5385
IRS2	5337
DUSP4	5253
ETV4	5179
CAMK2G	5094
FGF10	5079
RASGEF1A	4991
DAB2IP	4908
PPP2R5E	4871
SEM1	4832
PSME1	4820
ERBB2	4769
MARK3	4756
JAK3	4744
CDC14B	4694
PSMB8	4635
RGL2	4515
RASAL1	4507
KITLG	4497
MAP2K1	4420
GRB2	4417
PTPN7	4311
BRAF	4204
EGFR	4196
ABHD17B	4174
SHC1	4171
IL2RA	4129
RAF1	4106
TNRC6B	3765
PIK3CA	3688
UBC	3678
RASGRP4	3627
MAPK4	3271
CDC42EP3	3150
PAK2	3046
PIK3R2	3041
PTPN3	3015
SPTAN1	2944
IRS1	2940
FNTA	2855
PSMA6	2818
RCE1	2749
GFRA3	2707
RASAL2	2574
CAMK2D	2571
TYK2	2525
CALM1	2514
IGF2BP1	2508
LAMTOR2	2432
PPP1CB	2417
IL5	2323
ACTB	2300
JAK2	2278
PSMD5	1955
PSMC2	1937
PSMB9	1892
PSMD14	1828
CAMK2B	1772
IL3	1745
PTK2	1701
FRS2	1660
PSMD2	1596
RAG2	1411
PPP2R5C	1388
FOXO1	1323
SPRED2	1315
CSF2RB	1273
SHOC2	1153
PSMB1	1087
PDGFA	1044
PEBP1	1007
ABHD17A	929
FGFR1	835
SPTBN1	767
PSMB4	682
SRC	626
MOV10	519
PIK3R1	517
ARTN	406
PSMB7	389
FN1	363
AGO3	328
PPP2R1B	276
SPTB	269
WDR83	204
RASGRF2	144
MAPK6	-26
NRG3	-85
BRAP	-96
AGO2	-342
PSMD1	-344
IQGAP1	-406
MAP3K11	-409
GFRA2	-447
GRIN2B	-473
PSMB11	-633
SHC2	-734
PTPRA	-749
ACTN2	-756
RGL1	-761
NRAS	-916
LYPLA1	-959
FYN	-1025
PSMA3	-1034
MET	-1327
DNAJB1	-1427
RASGRF1	-1670
NF1	-1961
PSMC6	-1967
PSMD4	-2016
VCL	-2052
KSR2	-2103
RASGRP3	-2152
MAP2K2	-2192
PPP2R5A	-2220
JAK1	-2273
PSMD3	-2284
ARRB2	-2406
DLG1	-2409
NRG1	-2419
ERBB4	-2445
NCAM1	-2460
FLT3	-2486
PSMD6	-2567
RALGDS	-2603
FOXO3	-2607
KRAS	-2609
ARL2	-2668
PSMA7	-2741
FGF2	-2778
GOLGA7	-3050
PSMF1	-3068
PRKG2	-3131
PPP5C	-3137
CDK1	-3232
IL5RA	-3254
BTC	-3260
HBEGF	-3276
RASA2	-3407
NCOA3	-3444
DUSP10	-3542
PSMB2	-3711
CUL3	-3712
NRG4	-3939
VWF	-3957
PSMD12	-4181
PSMD7	-4231
RET	-4257
PSPN	-4320
PSMC4	-4337
DUSP16	-4360
DLG2	-4501
PRKCQ	-4559
SOS1	-4686
RASA3	-4692
RGL3	-4705
DUSP6	-4725
KALRN	-4756
RAPGEF2	-4831
PDGFRB	-4840
UBB	-4879
CSK	-4975
TNRC6C	-5013
PAK1	-5045
XPO1	-5236
CDC42	-5289
APBB1IP	-5524
TGFA	-5802
PSMA1	-5911
KIT	-6147
ARRB1	-6466
SPTBN5	-6507
FGF18	-6573
EGF	-6578
PRKACB	-6617
MMP10	-6652
DUSP8	-6672
PIK3CB	-6726
RASGRP1	-6762
FGF7	-6850
CDC14A	-6953
LRRC7	-7112
RAP1A	-7201
PSMC5	-7244
ANGPT1	-7309
NRTN	-7325
IL6	-7357
PEA15	-7542
LAMTOR3	-7596
FGG	-7631
PSMA8	-8172
CSF2	-8423
EPGN	-8569

---

REACTOME_FRS_MEDIATED_FGFR1_SIGNALING

REACTOME_FRS_MEDIATED_FGFR1_SIGNALING

	940
set	REACTOME_FRS_MEDIATED_FGFR1_SIGNALING
setSize	23
pANOVA	0.00366
s.dist	0.35
p.adjustANOVA	0.154

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FGF20	11659
FGF5	10861
HRAS	10478
FGF22	10147
FGF17	9443
FGF4	8965
FGF9	8830
FRS3	8566
FGF8	8081
FGF3	7841
KL	7480
FGF6	7242
FGF1	6404
PTPN11	6327
FGF23	5385
FGF10	5079
GRB2	4417
FRS2	1660
FGFR1	835
NRAS	-916

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FGF20	11659
FGF5	10861
HRAS	10478
FGF22	10147
FGF17	9443
FGF4	8965
FGF9	8830
FRS3	8566
FGF8	8081
FGF3	7841
KL	7480
FGF6	7242
FGF1	6404
PTPN11	6327
FGF23	5385
FGF10	5079
GRB2	4417
FRS2	1660
FGFR1	835
NRAS	-916
KRAS	-2609
FGF2	-2778
SOS1	-4686

---

REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION

REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION

	367
set	REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION
setSize	59
pANOVA	0.00397
s.dist	0.217
p.adjustANOVA	0.163

Top enriched genes

Top 20 genes

GeneID	Gene Rank
REST	12191
VRK3	11890
ID2	11698
DUSP7	11638
PPP2CB	11602
CDK5R1	11233
ID1	10966
F3	10901
MAPK3	10376
FOSL1	9988
PPP2R5D	9622
MAPK1	9390
TPH1	8540
EGR1	8378
DUSP3	8303
TRIB1	8285
JUNB	8209
ID4	7666
FOS	7444
VGF	7386

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
REST	12191
VRK3	11890
ID2	11698
DUSP7	11638
PPP2CB	11602
CDK5R1	11233
ID1	10966
F3	10901
MAPK3	10376
FOSL1	9988
PPP2R5D	9622
MAPK1	9390
TPH1	8540
EGR1	8378
DUSP3	8303
TRIB1	8285
JUNB	8209
ID4	7666
FOS	7444
VGF	7386
PPP2R1A	7026
FOSB	6949
RRAD	6883
PPP2CA	6858
MAPK11	6753
ATF1	6513
ID3	6433
CDK5R2	6106
MAPK7	5876
CHD4	5586
SH3GL3	5462
DUSP4	5253
DNM2	4508
ARC	3333
SRF	3237
MEF2D	3203
EGR3	3057
MEF2A	1698
RPS6KA5	1642
EGR4	586
CDK5	570
SGK1	511
LYL1	419
PPP2R1B	276
MAPKAPK2	69
NAB1	2
EGR2	-379
MEF2C	-2129
RPS6KA2	-2353
CREB1	-2546
NAB2	-3183
JUND	-3349
ATF2	-3745
MAPK14	-4217
DUSP6	-4725
TCF12	-5372
ASCL1	-5987
RPS6KA1	-6399
EP300	-6560

---

REACTOME_SIGNALING_BY_FGFR4

REACTOME_SIGNALING_BY_FGFR4

	959
set	REACTOME_SIGNALING_BY_FGFR4
setSize	40
pANOVA	0.00416
s.dist	0.262
p.adjustANOVA	0.167

Top enriched genes

Top 20 genes

GeneID	Gene Rank
UBA52	12048
FGF20	11659
PPP2CB	11602
HRAS	10478
MAPK3	10376
FGF17	9443
MAPK1	9390
FGF4	8965
FGF9	8830
FRS3	8566
PLCG1	8474
FGF19	8372
FGF8	8081
FGFR4	7821
FGF6	7242
PPP2R1A	7026
PPP2CA	6858
RPS27A	6760
FGF1	6404
PTPN11	6327

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
UBA52	12048
FGF20	11659
PPP2CB	11602
HRAS	10478
MAPK3	10376
FGF17	9443
MAPK1	9390
FGF4	8965
FGF9	8830
FRS3	8566
PLCG1	8474
FGF19	8372
FGF8	8081
FGFR4	7821
FGF6	7242
PPP2R1A	7026
PPP2CA	6858
RPS27A	6760
FGF1	6404
PTPN11	6327
KLB	5388
FGF23	5385
SPRY2	4430
GRB2	4417
BRAF	4204
SHC1	4171
PIK3CA	3688
UBC	3678
FRS2	1660
SRC	626
PIK3R1	517
GAB1	-61
NRAS	-916
CBL	-1592
KRAS	-2609
FGF2	-2778
MKNK1	-3811
SOS1	-4686
UBB	-4879
FGF18	-6573

---

REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR1

REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR1

	937
set	REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR1
setSize	31
pANOVA	0.005
s.dist	0.291
p.adjustANOVA	0.193

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FGF20	11659
FLRT1	11382
FGF5	10861
HRAS	10478
FGF22	10147
FGF17	9443
FGF4	8965
FGF9	8830
FRS3	8566
PLCG1	8474
FGF8	8081
FGF3	7841
KL	7480
FGF6	7242
FGF1	6404
PTPN11	6327
FGF23	5385
FGF10	5079
GRB2	4417
SHC1	4171

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FGF20	11659
FLRT1	11382
FGF5	10861
HRAS	10478
FGF22	10147
FGF17	9443
FGF4	8965
FGF9	8830
FRS3	8566
PLCG1	8474
FGF8	8081
FGF3	7841
KL	7480
FGF6	7242
FGF1	6404
PTPN11	6327
FGF23	5385
FGF10	5079
GRB2	4417
SHC1	4171
PIK3CA	3688
FRS2	1660
FGFR1	835
PIK3R1	517
FLRT2	110
GAB1	-61
NRAS	-916
KRAS	-2609
FGF2	-2778
FLRT3	-3549
SOS1	-4686

---

REACTOME_BBSOME_MEDIATED_CARGO_TARGETING_TO_CILIUM

REACTOME_BBSOME_MEDIATED_CARGO_TARGETING_TO_CILIUM

	909
set	REACTOME_BBSOME_MEDIATED_CARGO_TARGETING_TO_CILIUM
setSize	23
pANOVA	0.00505
s.dist	0.338
p.adjustANOVA	0.193

Top enriched genes

Top 20 genes

GeneID	Gene Rank
BBS12	12368
MCHR1	12284
ARL6	10811
BBS4	10726
CCT8	10284
CCT3	9740
SSTR3	9666
CCT5	8421
MKKS	8232
BBS10	8034
SMO	7899
CCT2	7429
BBIP1	6633
BBS5	4155
BBS2	3753
RAB3IP	2201
TCP1	910
TTC8	50
BBS9	-86
CCT4	-252

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
BBS12	12368
MCHR1	12284
ARL6	10811
BBS4	10726
CCT8	10284
CCT3	9740
SSTR3	9666
CCT5	8421
MKKS	8232
BBS10	8034
SMO	7899
CCT2	7429
BBIP1	6633
BBS5	4155
BBS2	3753
RAB3IP	2201
TCP1	910
TTC8	50
BBS9	-86
CCT4	-252
LZTFL1	-1150
BBS1	-2059
BBS7	-4453

---

REACTOME_SIGNALING_BY_NTRKS

REACTOME_SIGNALING_BY_NTRKS

	211
set	REACTOME_SIGNALING_BY_NTRKS
setSize	132
pANOVA	0.00535
s.dist	0.14
p.adjustANOVA	0.2

Top enriched genes

Top 20 genes

GeneID	Gene Rank
REST	12191
VRK3	11890
ID2	11698
DUSP7	11638
PPP2CB	11602
NTF4	11537
CDK5R1	11233
MAPK13	11116
ID1	10966
F3	10901
HRAS	10478
MAPK3	10376
SHC3	10168
TIAM1	10051
FOSL1	9988
PPP2R5D	9622
ADCYAP1R1	9579
MAPK1	9390
ADORA2A	9128
YWHAB	9072

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
REST	12191
VRK3	11890
ID2	11698
DUSP7	11638
PPP2CB	11602
NTF4	11537
CDK5R1	11233
MAPK13	11116
ID1	10966
F3	10901
HRAS	10478
MAPK3	10376
SHC3	10168
TIAM1	10051
FOSL1	9988
PPP2R5D	9622
ADCYAP1R1	9579
MAPK1	9390
ADORA2A	9128
YWHAB	9072
FRS3	8566
TPH1	8540
PLCG1	8474
EGR1	8378
DUSP3	8303
TRIB1	8285
MAPK12	8274
MAP2K5	8253
JUNB	8209
RAPGEF1	8202
AP2M1	8022
ID4	7666
FOS	7444
VGF	7386
PCSK5	7198
PPP2R1A	7026
FOSB	6949
RRAD	6883
RAC1	6880
PPP2CA	6858
MAPK11	6753
NTF3	6657
ATF1	6513
ID3	6433
PCSK6	6352
PTPN11	6327
CDK5R2	6106
RHOA	5999
MAPK7	5876
CHD4	5586
SH3GL3	5462
NTRK2	5424
IRS2	5337
BDNF	5260
DUSP4	5253
DNM1	5204
NGF	5129
NTRK3	4578
DNM2	4508
MAP2K1	4420
GRB2	4417
DOCK3	4213
BRAF	4204
SHC1	4171
NTRK1	4017
PIK3CA	3688
CRK	3673
ARC	3333
SRF	3237
CLTA	3232
MEF2D	3203
EGR3	3057
PIK3R2	3041
IRS1	2940
RIT1	2798
DNAL4	2786
RIT2	2624
SH3GL2	2478
PTPRO	2189
PTPRS	2183
BAX	1844
MEF2A	1698
FRS2	1660
RPS6KA5	1642
SRC	626
EGR4	586
CDK5	570
PIK3R1	517
SGK1	511
LYL1	419
PPP2R1B	276
MAPKAPK2	69
NAB1	2
GAB1	-61
EGR2	-379
GRIN2B	-473
AP2A1	-596
RALA	-693
SHC2	-734
RALB	-861
NRAS	-916
FYN	-1025
CRKL	-1302
ADCYAP1	-1538
DNM3	-1541
NELFB	-1691
MEF2C	-2129
MAP2K2	-2192
FURIN	-2200
RPS6KA2	-2353
CREB1	-2546
RALGDS	-2603
KRAS	-2609
AP2A2	-2814
NAB2	-3183
CLTC	-3186
JUND	-3349
ATF2	-3745
MAPK14	-4217
AP2B1	-4543
SOS1	-4686
DUSP6	-4725
KIDINS220	-4890
AP2S1	-5011
TCF12	-5372
ASCL1	-5987
MAPKAPK3	-6371
RPS6KA1	-6399
EP300	-6560
STAT3	-6570
PIK3CB	-6726
RAP1A	-7201

---

REACTOME_SHC_MEDIATED_CASCADE_FGFR1

REACTOME_SHC_MEDIATED_CASCADE_FGFR1

	938
set	REACTOME_SHC_MEDIATED_CASCADE_FGFR1
setSize	21
pANOVA	0.00623
s.dist	0.345
p.adjustANOVA	0.227

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FGF20	11659
FGF5	10861
HRAS	10478
FGF22	10147
FGF17	9443
FGF4	8965
FGF9	8830
FGF8	8081
FGF3	7841
KL	7480
FGF6	7242
FGF1	6404
FGF23	5385
FGF10	5079
GRB2	4417
SHC1	4171
FGFR1	835
NRAS	-916
KRAS	-2609
FGF2	-2778

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FGF20	11659
FGF5	10861
HRAS	10478
FGF22	10147
FGF17	9443
FGF4	8965
FGF9	8830
FGF8	8081
FGF3	7841
KL	7480
FGF6	7242
FGF1	6404
FGF23	5385
FGF10	5079
GRB2	4417
SHC1	4171
FGFR1	835
NRAS	-916
KRAS	-2609
FGF2	-2778
SOS1	-4686

---

REACTOME_WNT_LIGAND_BIOGENESIS_AND_TRAFFICKING

REACTOME_WNT_LIGAND_BIOGENESIS_AND_TRAFFICKING

	557
set	REACTOME_WNT_LIGAND_BIOGENESIS_AND_TRAFFICKING
setSize	25
pANOVA	0.00688
s.dist	0.312
p.adjustANOVA	0.246

Top enriched genes

Top 20 genes

GeneID	Gene Rank
WNT9B	11481
WNT3A	11036
WNT7B	11028
WNT6	10592
VPS26A	10438
WNT10A	10079
TMED5	9896
WNT3	9551
WNT10B	9179
WNT2B	7896
WLS	6108
SNX3	5918
VPS29	5527
WNT1	5283
WNT9A	4987
WNT5B	4636
VPS35	4361
WNT8B	4209
WNT5A	4094
WNT4	3640

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
WNT9B	11481
WNT3A	11036
WNT7B	11028
WNT6	10592
VPS26A	10438
WNT10A	10079
TMED5	9896
WNT3	9551
WNT10B	9179
WNT2B	7896
WLS	6108
SNX3	5918
VPS29	5527
WNT1	5283
WNT9A	4987
WNT5B	4636
VPS35	4361
WNT8B	4209
WNT5A	4094
WNT4	3640
WNT11	1717
WNT7A	-3718
WNT2	-4455
WNT16	-5346
WNT8A	-8614

---

REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_EARLY_PANCREATIC_PRECURSOR_CELLS

REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_EARLY_PANCREATIC_PRECURSOR_CELLS

	422
set	REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_EARLY_PANCREATIC_PRECURSOR_CELLS
setSize	8
pANOVA	0.00705
s.dist	0.55
p.adjustANOVA	0.246

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NKX6-1	10821
HNF1B	10045
PDX1	9227
NR5A2	7775
PTF1A	7432
ONECUT1	6863
ONECUT3	5152
FGF10	5079

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
NKX6-1	10821
HNF1B	10045
PDX1	9227
NR5A2	7775
PTF1A	7432
ONECUT1	6863
ONECUT3	5152
FGF10	5079

---

REACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE_FGFR2

REACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE_FGFR2

	935
set	REACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE_FGFR2
setSize	17
pANOVA	0.00759
s.dist	0.374
p.adjustANOVA	0.26

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FGF20	11659
FGF5	10861
FGF22	10147
FGF17	9443
FGF4	8965
FGF9	8830
PLCG1	8474
FGF8	8081
FGF3	7841
FGFR2	7428
FGF6	7242
FGF1	6404
FGF23	5385
FGF10	5079
FGF2	-2778
FGF18	-6573
FGF7	-6850

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FGF20	11659
FGF5	10861
FGF22	10147
FGF17	9443
FGF4	8965
FGF9	8830
PLCG1	8474
FGF8	8081
FGF3	7841
FGFR2	7428
FGF6	7242
FGF1	6404
FGF23	5385
FGF10	5079
FGF2	-2778
FGF18	-6573
FGF7	-6850

---

REACTOME_NEGATIVE_REGULATION_OF_MAPK_PATHWAY

REACTOME_NEGATIVE_REGULATION_OF_MAPK_PATHWAY

	986
set	REACTOME_NEGATIVE_REGULATION_OF_MAPK_PATHWAY
setSize	41
pANOVA	0.00779
s.dist	0.24
p.adjustANOVA	0.261

Top enriched genes

Top 20 genes

GeneID	Gene Rank
UBA52	12048
DUSP2	11924
DUSP7	11638
PPP2CB	11602
PAQR3	10686
HRAS	10478
MAPK3	10376
PPP2R5B	10174
DUSP5	9883
PPP2R5D	9622
MAPK1	9390
KSR1	9109
YWHAB	9072
DUSP1	9000
MAPK12	8274
PPP2R1A	7026
PPP2CA	6858
RPS27A	6760
DUSP4	5253
PPP2R5E	4871

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
UBA52	12048
DUSP2	11924
DUSP7	11638
PPP2CB	11602
PAQR3	10686
HRAS	10478
MAPK3	10376
PPP2R5B	10174
DUSP5	9883
PPP2R5D	9622
MAPK1	9390
KSR1	9109
YWHAB	9072
DUSP1	9000
MAPK12	8274
PPP2R1A	7026
PPP2CA	6858
RPS27A	6760
DUSP4	5253
PPP2R5E	4871
MARK3	4756
MAP2K1	4420
PTPN7	4311
BRAF	4204
RAF1	4106
UBC	3678
PTPN3	3015
PPP2R5C	1388
PEBP1	1007
PPP2R1B	276
BRAP	-96
NRAS	-916
MAP2K2	-2192
PPP2R5A	-2220
KRAS	-2609
PPP5C	-3137
DUSP10	-3542
DUSP16	-4360
DUSP6	-4725
UBB	-4879
DUSP8	-6672

---

REACTOME_FGFR1C_LIGAND_BINDING_AND_ACTIVATION

REACTOME_FGFR1C_LIGAND_BINDING_AND_ACTIVATION

	312
set	REACTOME_FGFR1C_LIGAND_BINDING_AND_ACTIVATION
setSize	11
pANOVA	0.0082
s.dist	0.46
p.adjustANOVA	0.269

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FGF20	11659
FGF5	10861
FGF17	9443
FGF4	8965
FGF9	8830
FGF8	8081
FGF6	7242
FGF1	6404
FGF23	5385
FGFR1	835
FGF2	-2778

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FGF20	11659
FGF5	10861
FGF17	9443
FGF4	8965
FGF9	8830
FGF8	8081
FGF6	7242
FGF1	6404
FGF23	5385
FGFR1	835
FGF2	-2778

---

Here is the session info with all the versions of packages used.

sessionInfo()

## R version 4.3.2 (2023-10-31)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.3 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3 
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so;  LAPACK version 3.10.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Etc/UTC
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.3.3                                      
##  [2] GGally_2.2.0                                       
##  [3] ggplot2_3.4.4                                      
##  [4] reshape2_1.4.4                                     
##  [5] gtools_3.9.5                                       
##  [6] tibble_3.2.1                                       
##  [7] dplyr_1.1.4                                        
##  [8] echarts4r_0.4.5                                    
##  [9] png_0.1-8                                          
## [10] gridExtra_2.3                                      
## [11] missMethyl_1.36.0                                  
## [12] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.1 
## [13] beeswarm_0.4.0                                     
## [14] kableExtra_1.3.4                                   
## [15] gplots_3.1.3                                       
## [16] mitch_1.15.0                                       
## [17] tictoc_1.2                                         
## [18] HGNChelper_0.8.1                                   
## [19] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [20] IlluminaHumanMethylation450kmanifest_0.4.0         
## [21] minfi_1.48.0                                       
## [22] bumphunter_1.44.0                                  
## [23] locfit_1.5-9.8                                     
## [24] iterators_1.0.14                                   
## [25] foreach_1.5.2                                      
## [26] Biostrings_2.70.1                                  
## [27] XVector_0.42.0                                     
## [28] SummarizedExperiment_1.32.0                        
## [29] Biobase_2.62.0                                     
## [30] MatrixGenerics_1.14.0                              
## [31] matrixStats_1.2.0                                  
## [32] GenomicRanges_1.54.1                               
## [33] GenomeInfoDb_1.38.2                                
## [34] IRanges_2.36.0                                     
## [35] S4Vectors_0.40.2                                   
## [36] BiocGenerics_0.48.1                                
## [37] eulerr_7.0.0                                       
## [38] limma_3.58.1                                       
## 
## loaded via a namespace (and not attached):
##   [1] splines_4.3.2             later_1.3.2              
##   [3] BiocIO_1.12.0             bitops_1.0-7             
##   [5] filelock_1.0.3            preprocessCore_1.64.0    
##   [7] XML_3.99-0.16             lifecycle_1.0.4          
##   [9] lattice_0.22-5            MASS_7.3-60              
##  [11] base64_2.0.1              scrime_1.3.5             
##  [13] magrittr_2.0.3            sass_0.4.8               
##  [15] rmarkdown_2.25            jquerylib_0.1.4          
##  [17] yaml_2.3.8                httpuv_1.6.13            
##  [19] doRNG_1.8.6               askpass_1.2.0            
##  [21] DBI_1.1.3                 RColorBrewer_1.1-3       
##  [23] abind_1.4-5               zlibbioc_1.48.0          
##  [25] rvest_1.0.3               quadprog_1.5-8           
##  [27] purrr_1.0.2               RCurl_1.98-1.13          
##  [29] rappdirs_0.3.3            GenomeInfoDbData_1.2.11  
##  [31] genefilter_1.84.0         annotate_1.80.0          
##  [33] svglite_2.1.3             DelayedMatrixStats_1.24.0
##  [35] codetools_0.2-19          DelayedArray_0.28.0      
##  [37] xml2_1.3.6                tidyselect_1.2.0         
##  [39] beanplot_1.3.1            BiocFileCache_2.10.1     
##  [41] webshot_0.5.5             illuminaio_0.44.0        
##  [43] GenomicAlignments_1.38.0  jsonlite_1.8.8           
##  [45] multtest_2.58.0           ellipsis_0.3.2           
##  [47] survival_3.5-7            systemfonts_1.0.5        
##  [49] tools_4.3.2               progress_1.2.3           
##  [51] Rcpp_1.0.11               glue_1.6.2               
##  [53] SparseArray_1.2.2         xfun_0.41                
##  [55] HDF5Array_1.30.0          withr_2.5.2              
##  [57] fastmap_1.1.1             rhdf5filters_1.14.1      
##  [59] fansi_1.0.6               openssl_2.1.1            
##  [61] caTools_1.18.2            digest_0.6.33            
##  [63] R6_2.5.1                  mime_0.12                
##  [65] colorspace_2.1-0          biomaRt_2.58.0           
##  [67] RSQLite_2.3.4             utf8_1.2.4               
##  [69] tidyr_1.3.0               generics_0.1.3           
##  [71] data.table_1.14.10        rtracklayer_1.62.0       
##  [73] prettyunits_1.2.0         httr_1.4.7               
##  [75] htmlwidgets_1.6.4         S4Arrays_1.2.0           
##  [77] ggstats_0.5.1             pkgconfig_2.0.3          
##  [79] gtable_0.3.4              blob_1.2.4               
##  [81] siggenes_1.76.0           htmltools_0.5.7          
##  [83] scales_1.3.0              rstudioapi_0.15.0        
##  [85] knitr_1.45                tzdb_0.4.0               
##  [87] rjson_0.2.21              nlme_3.1-163             
##  [89] curl_5.2.0                org.Hs.eg.db_3.18.0      
##  [91] cachem_1.0.8              rhdf5_2.46.1             
##  [93] stringr_1.5.1             KernSmooth_2.23-22       
##  [95] AnnotationDbi_1.64.1      restfulr_0.0.15          
##  [97] GEOquery_2.70.0           pillar_1.9.0             
##  [99] grid_4.3.2                reshape_0.8.9            
## [101] vctrs_0.6.5               promises_1.2.1           
## [103] dbplyr_2.4.0              xtable_1.8-4             
## [105] evaluate_0.23             readr_2.1.4              
## [107] GenomicFeatures_1.54.1    cli_3.6.2                
## [109] compiler_4.3.2            Rsamtools_2.18.0         
## [111] rlang_1.1.2               crayon_1.5.2             
## [113] rngtools_1.5.2            nor1mix_1.3-2            
## [115] mclust_6.0.1              plyr_1.8.9               
## [117] stringi_1.8.3             viridisLite_0.4.2        
## [119] BiocParallel_1.36.0       munsell_0.5.0            
## [121] Matrix_1.6-1.1            hms_1.1.3                
## [123] sparseMatrixStats_1.14.0  bit64_4.0.5              
## [125] Rhdf5lib_1.24.1           KEGGREST_1.42.0          
## [127] statmod_1.5.0             shiny_1.8.0              
## [129] highr_0.10                memoise_2.0.1            
## [131] bslib_0.6.1               bit_4.0.5

END of report