date generated: 2024-01-18

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch
x
A1BG -0.0001830
A1BG-AS1 -0.0002571
A1CF -0.0001925
A2M -0.0004189
A2M-AS1 -0.0002711
A2ML1 -0.0000188

Here are some metrics about the input data profile:

Profiling data metrics
Profile metrics
num_genesets 1654
num_genes_in_profile 22007
duplicated_genes_present 0
num_profile_genes_in_sets 10383
num_profile_genes_not_in_sets 11624

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets: c2.cp.reactome.v2023.1.Hs.symbols.gmt
Gene set metrics
Gene sets metrics
num_genesets 1654
num_genesets_excluded 365
num_genesets_included 1289

Differential pathway expression


Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

## Warning in kable_styling(., "hover", full_width = FALSE): Please specify format
## in kable. kableExtra can customize either HTML or LaTeX outputs. See
## https://haozhu233.github.io/kableExtra/ for details.
set setSize pANOVA s.dist p.adjustANOVA
REACTOME CHROMATIN MODIFYING ENZYMES 252 1.83e-09 -0.2200 3.01e-06
REACTOME NEUTROPHIL DEGRANULATION 460 1.07e-06 0.1330 8.76e-04
REACTOME HATS ACETYLATE HISTONES 129 3.67e-06 -0.2360 2.01e-03
REACTOME GPCR LIGAND BINDING 444 1.13e-05 0.1220 4.64e-03
REACTOME SIGNALING BY GPCR 673 1.21e-04 0.0869 3.99e-02
REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS 312 1.58e-04 0.1240 4.33e-02
REACTOME INNATE IMMUNE SYSTEM 1002 4.08e-04 0.0660 7.74e-02
REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX 85 4.39e-04 -0.2210 7.74e-02
REACTOME CELL CYCLE 666 4.71e-04 -0.0794 7.74e-02
REACTOME METABOLISM OF RNA 675 4.72e-04 -0.0789 7.74e-02
REACTOME DNA REPAIR 321 7.88e-04 -0.1090 1.18e-01
REACTOME PKMTS METHYLATE HISTONE LYSINES 64 8.60e-04 -0.2410 1.18e-01
REACTOME GENERATION OF SECOND MESSENGER MOLECULES 30 1.49e-03 -0.3350 1.75e-01
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA 263 1.59e-03 -0.1130 1.75e-01
REACTOME TRNA PROCESSING 105 1.60e-03 -0.1780 1.75e-01
REACTOME INTERLEUKIN 10 SIGNALING 43 1.77e-03 0.2750 1.82e-01
REACTOME MRNA SPLICING 197 1.97e-03 -0.1280 1.90e-01
REACTOME NEURONAL SYSTEM 388 2.81e-03 0.0884 2.43e-01
REACTOME HDACS DEACETYLATE HISTONES 85 2.90e-03 -0.1870 2.43e-01
REACTOME BASE EXCISION REPAIR 87 2.96e-03 -0.1840 2.43e-01
REACTOME CELL CYCLE MITOTIC 539 3.77e-03 -0.0729 2.95e-01
REACTOME RMTS METHYLATE HISTONE ARGININES 72 4.55e-03 -0.1930 3.31e-01
REACTOME DEVELOPMENTAL BIOLOGY 1115 4.85e-03 0.0500 3.31e-01
REACTOME CILIUM ASSEMBLY 190 5.12e-03 -0.1180 3.31e-01
REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS 93 5.18e-03 0.1680 3.31e-01
REACTOME PHASE 3 RAPID REPOLARISATION 8 5.24e-03 0.5700 3.31e-01
REACTOME G ALPHA S SIGNALLING EVENTS 155 5.45e-03 0.1290 3.31e-01
REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION 90 5.89e-03 -0.1680 3.42e-01
REACTOME DNA DOUBLE STRAND BREAK REPAIR 162 6.32e-03 -0.1240 3.42e-01
REACTOME PEPTIDE HORMONE BIOSYNTHESIS 13 6.37e-03 0.4370 3.42e-01
REACTOME TELOMERE MAINTENANCE 106 6.76e-03 -0.1520 3.42e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION 29 6.96e-03 -0.2900 3.42e-01
REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE 93 6.96e-03 -0.1620 3.42e-01
REACTOME NUCLEOTIDE EXCISION REPAIR 107 7.08e-03 -0.1510 3.42e-01
REACTOME MEIOSIS 110 7.60e-03 -0.1470 3.53e-01
REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX 57 7.73e-03 -0.2040 3.53e-01
REACTOME HOMOLOGY DIRECTED REPAIR 132 7.97e-03 -0.1340 3.54e-01
REACTOME NERVOUS SYSTEM DEVELOPMENT 552 8.63e-03 0.0654 3.63e-01
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION 138 8.75e-03 -0.1290 3.63e-01
REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES 18 9.74e-03 -0.3520 3.63e-01
REACTOME LDL REMODELING 6 9.80e-03 0.6090 3.63e-01
REACTOME AURKA ACTIVATION BY TPX2 69 9.86e-03 -0.1800 3.63e-01
REACTOME MEIOTIC SYNAPSIS 73 1.00e-02 -0.1740 3.63e-01
REACTOME EICOSANOID LIGAND BINDING RECEPTORS 14 1.05e-02 0.3950 3.63e-01
REACTOME PEPTIDE LIGAND BINDING RECEPTORS 188 1.05e-02 0.1080 3.63e-01
REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS 43 1.06e-02 -0.2250 3.63e-01
REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE 19 1.06e-02 -0.3380 3.63e-01
REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL 41 1.07e-02 -0.2300 3.63e-01
REACTOME REPRODUCTION 136 1.08e-02 -0.1270 3.63e-01
REACTOME DEFECTIVE CSF2RB CAUSES SMDP5 7 1.14e-02 0.5520 3.70e-01


Results (complete table)


Click HERE to show results for all gene sets

Complete results
set setSize pANOVA s.dist p.adjustANOVA
REACTOME CHROMATIN MODIFYING ENZYMES 252 1.83e-09 -2.20e-01 3.01e-06
REACTOME NEUTROPHIL DEGRANULATION 460 1.07e-06 1.33e-01 8.76e-04
REACTOME HATS ACETYLATE HISTONES 129 3.67e-06 -2.36e-01 2.01e-03
REACTOME GPCR LIGAND BINDING 444 1.13e-05 1.22e-01 4.64e-03
REACTOME SIGNALING BY GPCR 673 1.21e-04 8.69e-02 3.99e-02
REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS 312 1.58e-04 1.24e-01 4.33e-02
REACTOME INNATE IMMUNE SYSTEM 1002 4.08e-04 6.60e-02 7.74e-02
REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX 85 4.39e-04 -2.21e-01 7.74e-02
REACTOME CELL CYCLE 666 4.71e-04 -7.94e-02 7.74e-02
REACTOME METABOLISM OF RNA 675 4.72e-04 -7.89e-02 7.74e-02
REACTOME DNA REPAIR 321 7.88e-04 -1.09e-01 1.18e-01
REACTOME PKMTS METHYLATE HISTONE LYSINES 64 8.60e-04 -2.41e-01 1.18e-01
REACTOME GENERATION OF SECOND MESSENGER MOLECULES 30 1.49e-03 -3.35e-01 1.75e-01
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA 263 1.59e-03 -1.13e-01 1.75e-01
REACTOME TRNA PROCESSING 105 1.60e-03 -1.78e-01 1.75e-01
REACTOME INTERLEUKIN 10 SIGNALING 43 1.77e-03 2.75e-01 1.82e-01
REACTOME MRNA SPLICING 197 1.97e-03 -1.28e-01 1.90e-01
REACTOME NEURONAL SYSTEM 388 2.81e-03 8.84e-02 2.43e-01
REACTOME HDACS DEACETYLATE HISTONES 85 2.90e-03 -1.87e-01 2.43e-01
REACTOME BASE EXCISION REPAIR 87 2.96e-03 -1.84e-01 2.43e-01
REACTOME CELL CYCLE MITOTIC 539 3.77e-03 -7.29e-02 2.95e-01
REACTOME RMTS METHYLATE HISTONE ARGININES 72 4.55e-03 -1.93e-01 3.31e-01
REACTOME DEVELOPMENTAL BIOLOGY 1115 4.85e-03 5.00e-02 3.31e-01
REACTOME CILIUM ASSEMBLY 190 5.12e-03 -1.18e-01 3.31e-01
REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS 93 5.18e-03 1.68e-01 3.31e-01
REACTOME PHASE 3 RAPID REPOLARISATION 8 5.24e-03 5.70e-01 3.31e-01
REACTOME G ALPHA S SIGNALLING EVENTS 155 5.45e-03 1.29e-01 3.31e-01
REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION 90 5.89e-03 -1.68e-01 3.42e-01
REACTOME DNA DOUBLE STRAND BREAK REPAIR 162 6.32e-03 -1.24e-01 3.42e-01
REACTOME PEPTIDE HORMONE BIOSYNTHESIS 13 6.37e-03 4.37e-01 3.42e-01
REACTOME TELOMERE MAINTENANCE 106 6.76e-03 -1.52e-01 3.42e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION 29 6.96e-03 -2.90e-01 3.42e-01
REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE 93 6.96e-03 -1.62e-01 3.42e-01
REACTOME NUCLEOTIDE EXCISION REPAIR 107 7.08e-03 -1.51e-01 3.42e-01
REACTOME MEIOSIS 110 7.60e-03 -1.47e-01 3.53e-01
REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX 57 7.73e-03 -2.04e-01 3.53e-01
REACTOME HOMOLOGY DIRECTED REPAIR 132 7.97e-03 -1.34e-01 3.54e-01
REACTOME NERVOUS SYSTEM DEVELOPMENT 552 8.63e-03 6.54e-02 3.63e-01
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION 138 8.75e-03 -1.29e-01 3.63e-01
REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES 18 9.74e-03 -3.52e-01 3.63e-01
REACTOME LDL REMODELING 6 9.80e-03 6.09e-01 3.63e-01
REACTOME AURKA ACTIVATION BY TPX2 69 9.86e-03 -1.80e-01 3.63e-01
REACTOME MEIOTIC SYNAPSIS 73 1.00e-02 -1.74e-01 3.63e-01
REACTOME EICOSANOID LIGAND BINDING RECEPTORS 14 1.05e-02 3.95e-01 3.63e-01
REACTOME PEPTIDE LIGAND BINDING RECEPTORS 188 1.05e-02 1.08e-01 3.63e-01
REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS 43 1.06e-02 -2.25e-01 3.63e-01
REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE 19 1.06e-02 -3.38e-01 3.63e-01
REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL 41 1.07e-02 -2.30e-01 3.63e-01
REACTOME REPRODUCTION 136 1.08e-02 -1.27e-01 3.63e-01
REACTOME DEFECTIVE CSF2RB CAUSES SMDP5 7 1.14e-02 5.52e-01 3.70e-01
REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE 52 1.15e-02 -2.03e-01 3.70e-01
REACTOME VOLTAGE GATED POTASSIUM CHANNELS 42 1.20e-02 2.24e-01 3.80e-01
REACTOME RNA POLYMERASE II PRE TRANSCRIPTION EVENTS 77 1.24e-02 -1.65e-01 3.81e-01
REACTOME INFLAMMASOMES 21 1.25e-02 3.15e-01 3.81e-01
REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND 14 1.35e-02 -3.81e-01 3.97e-01
REACTOME CELLULAR SENESCENCE 189 1.35e-02 -1.04e-01 3.97e-01
REACTOME PYRIMIDINE SALVAGE 10 1.40e-02 4.49e-01 4.02e-01
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION 1356 1.56e-02 -3.92e-02 4.40e-01
REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE 11 1.62e-02 4.19e-01 4.44e-01
REACTOME PRE NOTCH EXPRESSION AND PROCESSING 112 1.62e-02 -1.31e-01 4.44e-01
REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES 78 1.67e-02 -1.57e-01 4.45e-01
REACTOME DEUBIQUITINATION 260 1.70e-02 -8.60e-02 4.45e-01
REACTOME DNA DOUBLE STRAND BREAK RESPONSE 74 1.71e-02 -1.60e-01 4.45e-01
REACTOME OTHER SEMAPHORIN INTERACTIONS 18 1.76e-02 3.23e-01 4.47e-01
REACTOME HCMV LATE EVENTS 110 1.77e-02 -1.31e-01 4.47e-01
REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS 100 1.88e-02 -1.36e-01 4.61e-01
REACTOME DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE 76 1.92e-02 -1.55e-01 4.61e-01
REACTOME SODIUM COUPLED PHOSPHATE COTRANSPORTERS 5 1.96e-02 6.03e-01 4.61e-01
REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER 81 1.98e-02 -1.50e-01 4.61e-01
REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS 16 2.08e-02 3.34e-01 4.61e-01
REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 98 2.11e-02 -1.35e-01 4.61e-01
REACTOME OLFACTORY SIGNALING PATHWAY 348 2.12e-02 -7.19e-02 4.61e-01
REACTOME CELL CELL COMMUNICATION 126 2.18e-02 1.18e-01 4.61e-01
REACTOME DEFECTIVE GALNT3 CAUSES HFTC 16 2.18e-02 -3.31e-01 4.61e-01
REACTOME MAPK3 ERK1 ACTIVATION 10 2.18e-02 -4.19e-01 4.61e-01
REACTOME SUMOYLATION OF DNA REPLICATION PROTEINS 46 2.19e-02 -1.95e-01 4.61e-01
REACTOME M PHASE 398 2.20e-02 -6.69e-02 4.61e-01
REACTOME PROCESSING OF DNA DOUBLE STRAND BREAK ENDS 93 2.25e-02 -1.37e-01 4.61e-01
REACTOME G ALPHA I SIGNALLING EVENTS 304 2.26e-02 7.60e-02 4.61e-01
REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS 8 2.26e-02 4.65e-01 4.61e-01
REACTOME BASE EXCISION REPAIR AP SITE FORMATION 59 2.30e-02 -1.71e-01 4.61e-01
REACTOME NONHOMOLOGOUS END JOINING NHEJ 64 2.33e-02 -1.64e-01 4.61e-01
REACTOME SUMOYLATION 179 2.35e-02 -9.81e-02 4.61e-01
REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE 63 2.40e-02 -1.64e-01 4.61e-01
REACTOME CALCITONIN LIKE LIGAND RECEPTORS 10 2.41e-02 4.12e-01 4.61e-01
REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION 296 2.41e-02 -7.62e-02 4.61e-01
REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR 11 2.48e-02 3.91e-01 4.62e-01
REACTOME SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS 16 2.48e-02 3.24e-01 4.62e-01
REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3 59 2.51e-02 -1.69e-01 4.62e-01
REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION 84 2.53e-02 -1.41e-01 4.62e-01
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL 122 2.65e-02 1.16e-01 4.73e-01
REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS 6 2.67e-02 -5.22e-01 4.73e-01
REACTOME CARDIAC CONDUCTION 125 2.70e-02 1.14e-01 4.73e-01
REACTOME HIV INFECTION 223 2.73e-02 -8.58e-02 4.73e-01
REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION 68 2.74e-02 -1.55e-01 4.73e-01
REACTOME DNA METHYLATION 58 2.81e-02 -1.67e-01 4.73e-01
REACTOME CHROMOSOME MAINTENANCE 130 2.82e-02 -1.11e-01 4.73e-01
REACTOME MEIOTIC RECOMBINATION 80 2.86e-02 -1.42e-01 4.73e-01
REACTOME DISEASES ASSOCIATED WITH SURFACTANT METABOLISM 9 2.86e-02 4.21e-01 4.73e-01
REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION 12 2.90e-02 3.64e-01 4.73e-01
REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION 60 2.92e-02 -1.63e-01 4.73e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH PI3K 7 2.94e-02 4.75e-01 4.73e-01
REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE 277 3.06e-02 -7.55e-02 4.84e-01
REACTOME SIGNALING BY NTRKS 132 3.13e-02 1.09e-01 4.84e-01
REACTOME ADHERENS JUNCTIONS INTERACTIONS 33 3.13e-02 2.17e-01 4.84e-01
REACTOME UB SPECIFIC PROCESSING PROTEASES 187 3.17e-02 -9.11e-02 4.84e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION 102 3.18e-02 -1.23e-01 4.84e-01
REACTOME ESTROGEN DEPENDENT GENE EXPRESSION 140 3.19e-02 -1.05e-01 4.84e-01
REACTOME POTASSIUM CHANNELS 102 3.22e-02 1.23e-01 4.84e-01
REACTOME TELOMERE C STRAND LAGGING STRAND SYNTHESIS 33 3.24e-02 -2.15e-01 4.84e-01
REACTOME PI 3K CASCADE FGFR4 19 3.35e-02 2.82e-01 4.96e-01
REACTOME PURINE CATABOLISM 17 3.46e-02 2.96e-01 4.99e-01
REACTOME AUTOPHAGY 144 3.51e-02 -1.02e-01 4.99e-01
REACTOME SIGNALING BY BMP 27 3.52e-02 2.34e-01 4.99e-01
REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP 104 3.55e-02 -1.19e-01 4.99e-01
REACTOME RHO GTPASES ACTIVATE PKNS 86 3.57e-02 -1.31e-01 4.99e-01
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES 255 3.59e-02 7.63e-02 4.99e-01
REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL 129 3.60e-02 1.07e-01 4.99e-01
REACTOME GENE SILENCING BY RNA 133 3.62e-02 -1.05e-01 4.99e-01
REACTOME DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS 19 3.82e-02 -2.75e-01 5.22e-01
REACTOME SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS 74 3.91e-02 -1.39e-01 5.30e-01
REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 100 4.01e-02 -1.19e-01 5.30e-01
REACTOME COLLAGEN DEGRADATION 61 4.06e-02 1.52e-01 5.30e-01
REACTOME CELL JUNCTION ORGANIZATION 89 4.08e-02 1.25e-01 5.30e-01
REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS 118 4.12e-02 1.09e-01 5.30e-01
REACTOME PD 1 SIGNALING 21 4.12e-02 -2.57e-01 5.30e-01
REACTOME LYSOSPHINGOLIPID AND LPA RECEPTORS 14 4.12e-02 3.15e-01 5.30e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES 29 4.14e-02 2.19e-01 5.30e-01
REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES 38 4.16e-02 1.91e-01 5.30e-01
REACTOME HCMV INFECTION 152 4.26e-02 -9.53e-02 5.39e-01
REACTOME TNF SIGNALING 54 4.30e-02 -1.59e-01 5.39e-01
REACTOME HCMV EARLY EVENTS 128 4.53e-02 -1.02e-01 5.48e-01
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES 55 4.55e-02 1.56e-01 5.48e-01
REACTOME TIE2 SIGNALING 18 4.56e-02 2.72e-01 5.48e-01
REACTOME TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER 76 4.58e-02 -1.32e-01 5.48e-01
REACTOME ASPIRIN ADME 42 4.59e-02 -1.78e-01 5.48e-01
REACTOME REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION 84 4.59e-02 -1.26e-01 5.48e-01
REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE 52 4.62e-02 -1.60e-01 5.48e-01
REACTOME ORGANIC ANION TRANSPORT 5 4.70e-02 -5.13e-01 5.48e-01
REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER 77 4.73e-02 1.31e-01 5.48e-01
REACTOME DEADENYLATION DEPENDENT MRNA DECAY 56 4.76e-02 -1.53e-01 5.48e-01
REACTOME EXTENSION OF TELOMERES 49 4.79e-02 -1.63e-01 5.48e-01
REACTOME PRC2 METHYLATES HISTONES AND DNA 65 4.84e-02 -1.42e-01 5.48e-01
REACTOME DNA REPLICATION 178 4.87e-02 -8.57e-02 5.48e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR4 26 4.87e-02 2.23e-01 5.48e-01
REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS 68 4.89e-02 -1.38e-01 5.48e-01
REACTOME SHC MEDIATED CASCADE FGFR4 19 4.95e-02 2.60e-01 5.48e-01
REACTOME GAB1 SIGNALOSOME 17 4.96e-02 2.75e-01 5.48e-01
REACTOME HEME DEGRADATION 15 5.00e-02 -2.92e-01 5.48e-01
REACTOME TRNA PROCESSING IN THE NUCLEUS 58 5.00e-02 -1.49e-01 5.48e-01
REACTOME DISEASES OF PROGRAMMED CELL DEATH 96 5.13e-02 -1.15e-01 5.50e-01
REACTOME MAPK1 ERK2 ACTIVATION 9 5.14e-02 -3.75e-01 5.50e-01
REACTOME ENDOSOMAL VACUOLAR PATHWAY 11 5.20e-02 3.38e-01 5.50e-01
REACTOME DNA DAMAGE RECOGNITION IN GG NER 36 5.22e-02 -1.87e-01 5.50e-01
REACTOME GAP JUNCTION ASSEMBLY 36 5.23e-02 1.87e-01 5.50e-01
REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS 53 5.29e-02 1.54e-01 5.50e-01
REACTOME METABOLISM OF PORPHYRINS 26 5.31e-02 -2.19e-01 5.50e-01
REACTOME NUCLEOTIDE CATABOLISM 35 5.32e-02 1.89e-01 5.50e-01
REACTOME HEMOSTASIS 591 5.33e-02 4.65e-02 5.50e-01
REACTOME REGULATION OF GENE EXPRESSION IN ENDOCRINE COMMITTED NEUROG3 PROGENITOR CELLS 5 5.41e-02 4.97e-01 5.55e-01
REACTOME SIGNALING BY EGFR 49 5.50e-02 1.58e-01 5.61e-01
REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION 26 5.55e-02 2.17e-01 5.62e-01
REACTOME LAGGING STRAND SYNTHESIS 19 5.62e-02 -2.53e-01 5.64e-01
REACTOME FORMATION OF THE CORNIFIED ENVELOPE 125 5.63e-02 9.88e-02 5.64e-01
REACTOME RUNX3 REGULATES P14 ARF 10 5.66e-02 -3.48e-01 5.64e-01
REACTOME PEPTIDE HORMONE METABOLISM 84 5.76e-02 1.20e-01 5.70e-01
REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS 21 5.81e-02 2.39e-01 5.71e-01
REACTOME GAP JUNCTION TRAFFICKING AND REGULATION 49 5.97e-02 1.55e-01 5.81e-01
REACTOME CONDENSATION OF PROPHASE CHROMOSOMES 66 5.98e-02 -1.34e-01 5.81e-01
REACTOME RNA POLYMERASE II TRANSCRIBES SNRNA GENES 77 6.02e-02 -1.24e-01 5.82e-01
REACTOME POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE 25 6.13e-02 -2.16e-01 5.87e-01
REACTOME AMINO ACID CONJUGATION 9 6.15e-02 3.60e-01 5.87e-01
REACTOME HIV LIFE CYCLE 145 6.36e-02 -8.92e-02 5.94e-01
REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS 16 6.50e-02 -2.66e-01 5.94e-01
REACTOME OXIDATIVE STRESS INDUCED SENESCENCE 118 6.54e-02 -9.82e-02 5.94e-01
REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION 62 6.55e-02 -1.35e-01 5.94e-01
REACTOME PI 3K CASCADE FGFR2 22 6.58e-02 2.27e-01 5.94e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH RAS 9 6.68e-02 3.53e-01 5.94e-01
REACTOME EXTRACELLULAR MATRIX ORGANIZATION 291 6.74e-02 6.23e-02 5.94e-01
REACTOME G2 M DNA DAMAGE CHECKPOINT 90 6.74e-02 -1.12e-01 5.94e-01
REACTOME SIGNALING BY MAPK MUTANTS 6 6.77e-02 4.31e-01 5.94e-01
REACTOME PTK6 PROMOTES HIF1A STABILIZATION 6 6.81e-02 4.30e-01 5.94e-01
REACTOME SIGNALLING TO RAS 20 6.81e-02 2.36e-01 5.94e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING 11 6.87e-02 3.17e-01 5.94e-01
REACTOME DEFECTIVE CHSY1 CAUSES TPBS 7 6.90e-02 3.97e-01 5.94e-01
REACTOME EUKARYOTIC TRANSLATION INITIATION 110 6.91e-02 1.00e-01 5.94e-01
REACTOME TCR SIGNALING 113 7.00e-02 -9.87e-02 5.94e-01
REACTOME TERMINAL PATHWAY OF COMPLEMENT 8 7.10e-02 3.69e-01 5.94e-01
REACTOME TRIGLYCERIDE METABOLISM 35 7.10e-02 1.76e-01 5.94e-01
REACTOME MUSCLE CONTRACTION 197 7.10e-02 7.46e-02 5.94e-01
REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS 27 7.18e-02 -2.00e-01 5.94e-01
REACTOME MRNA EDITING C TO U CONVERSION 8 7.18e-02 3.68e-01 5.94e-01
REACTOME METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION 15 7.19e-02 -2.68e-01 5.94e-01
REACTOME MRNA SPLICING MINOR PATHWAY 49 7.21e-02 -1.48e-01 5.94e-01
REACTOME PROSTANOID LIGAND RECEPTORS 9 7.22e-02 3.46e-01 5.94e-01
REACTOME ACYL CHAIN REMODELING OF DAG AND TAG 5 7.22e-02 4.64e-01 5.94e-01
REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY 51 7.22e-02 1.46e-01 5.94e-01
REACTOME SUMOYLATION OF SUMOYLATION PROTEINS 35 7.24e-02 -1.75e-01 5.94e-01
REACTOME RNA POLYMERASE I PROMOTER ESCAPE 83 7.25e-02 -1.14e-01 5.94e-01
REACTOME ESR MEDIATED SIGNALING 210 7.33e-02 -7.17e-02 5.94e-01
REACTOME TRIGLYCERIDE BIOSYNTHESIS 12 7.38e-02 2.98e-01 5.94e-01
REACTOME REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE 81 7.40e-02 -1.15e-01 5.94e-01
REACTOME UPTAKE AND FUNCTION OF ANTHRAX TOXINS 11 7.46e-02 -3.10e-01 5.94e-01
REACTOME PROCESSING AND ACTIVATION OF SUMO 10 7.49e-02 -3.25e-01 5.94e-01
REACTOME RET SIGNALING 40 7.50e-02 1.63e-01 5.94e-01
REACTOME SIGNALING BY RECEPTOR TYROSINE KINASES 507 7.51e-02 4.62e-02 5.94e-01
REACTOME MYOGENESIS 29 7.54e-02 1.91e-01 5.94e-01
REACTOME HOST INTERACTIONS OF HIV FACTORS 127 7.59e-02 -9.12e-02 5.94e-01
REACTOME NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION 193 7.63e-02 7.40e-02 5.94e-01
REACTOME G ALPHA Q SIGNALLING EVENTS 206 7.69e-02 7.15e-02 5.94e-01
REACTOME GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION 34 7.76e-02 -1.75e-01 5.94e-01
REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX 14 7.77e-02 -2.72e-01 5.94e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1 31 7.77e-02 1.83e-01 5.94e-01
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY 94 7.78e-02 1.05e-01 5.94e-01
REACTOME DNA REPLICATION PRE INITIATION 150 7.82e-02 -8.33e-02 5.94e-01
REACTOME CELL CYCLE CHECKPOINTS 284 7.82e-02 -6.07e-02 5.94e-01
REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS 20 7.91e-02 -2.27e-01 5.94e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS 15 7.92e-02 -2.62e-01 5.94e-01
REACTOME SIGNALLING TO P38 VIA RIT AND RIN 5 7.95e-02 4.53e-01 5.94e-01
REACTOME SIGNALING BY FGFR4 40 8.01e-02 1.60e-01 5.94e-01
REACTOME INTERLEUKIN 6 SIGNALING 11 8.02e-02 -3.05e-01 5.94e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR2 29 8.05e-02 1.88e-01 5.94e-01
REACTOME FRS MEDIATED FGFR4 SIGNALING 21 8.07e-02 2.20e-01 5.94e-01
REACTOME CELLULAR RESPONSE TO HEAT STRESS 99 8.16e-02 -1.01e-01 5.98e-01
REACTOME TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY 30 8.24e-02 -1.83e-01 6.00e-01
REACTOME TNFR1 INDUCED PROAPOPTOTIC SIGNALING 23 8.26e-02 -2.09e-01 6.00e-01
REACTOME VITAMIN B5 PANTOTHENATE METABOLISM 16 8.30e-02 2.50e-01 6.01e-01
REACTOME SUMOYLATION OF RNA BINDING PROTEINS 47 8.37e-02 -1.46e-01 6.02e-01
REACTOME SYNTHESIS OF LIPOXINS LX 6 8.63e-02 4.04e-01 6.18e-01
REACTOME HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS 7 8.68e-02 3.74e-01 6.18e-01
REACTOME TRANSPORT OF NUCLEOTIDE SUGARS 8 8.69e-02 3.50e-01 6.18e-01
REACTOME INDUCTION OF CELL CELL FUSION 12 8.73e-02 -2.85e-01 6.18e-01
REACTOME SIGNALING BY NOTCH 234 8.78e-02 -6.48e-02 6.19e-01
REACTOME PI 3K CASCADE FGFR3 17 8.90e-02 2.38e-01 6.24e-01
REACTOME SIGNALING BY ACTIVIN 15 9.05e-02 2.52e-01 6.27e-01
REACTOME CREATINE METABOLISM 9 9.12e-02 3.25e-01 6.27e-01
REACTOME REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS 7 9.12e-02 3.69e-01 6.27e-01
REACTOME SENSORY PERCEPTION 555 9.13e-02 -4.19e-02 6.27e-01
REACTOME SUMOYLATION OF IMMUNE RESPONSE PROTEINS 10 9.14e-02 -3.08e-01 6.27e-01
REACTOME HIV ELONGATION ARREST AND RECOVERY 33 9.20e-02 -1.69e-01 6.27e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1 229 9.20e-02 -6.46e-02 6.27e-01
REACTOME GLUCURONIDATION 23 9.26e-02 -2.03e-01 6.28e-01
REACTOME MRNA EDITING 10 9.29e-02 3.07e-01 6.28e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION 41 9.39e-02 -1.51e-01 6.32e-01
REACTOME COLLAGEN FORMATION 88 9.50e-02 1.03e-01 6.35e-01
REACTOME ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE 9 9.52e-02 3.21e-01 6.35e-01
REACTOME INTERLEUKIN 7 SIGNALING 31 9.61e-02 -1.73e-01 6.37e-01
REACTOME GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER 25 9.63e-02 -1.92e-01 6.37e-01
REACTOME SUMO IS TRANSFERRED FROM E1 TO E2 UBE2I UBC9 7 9.67e-02 -3.63e-01 6.37e-01
REACTOME THE PHOTOTRANSDUCTION CASCADE 32 9.71e-02 -1.69e-01 6.37e-01
REACTOME WAX AND PLASMALOGEN BIOSYNTHESIS 5 9.74e-02 4.28e-01 6.37e-01
REACTOME RECYCLING PATHWAY OF L1 43 9.98e-02 1.45e-01 6.44e-01
REACTOME THE NLRP3 INFLAMMASOME 16 9.99e-02 2.38e-01 6.44e-01
REACTOME NEDDYLATION 235 1.00e-01 -6.23e-02 6.44e-01
REACTOME CHOLESTEROL BIOSYNTHESIS 25 1.00e-01 -1.90e-01 6.44e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES 8 1.00e-01 3.35e-01 6.44e-01
REACTOME METABOLISM OF NUCLEOTIDES 94 1.02e-01 9.75e-02 6.53e-01
REACTOME LYSOSOME VESICLE BIOGENESIS 33 1.03e-01 1.64e-01 6.57e-01
REACTOME ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS 41 1.04e-01 1.47e-01 6.59e-01
REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT 159 1.04e-01 -7.46e-02 6.60e-01
REACTOME AMINO ACIDS REGULATE MTORC1 53 1.05e-01 -1.29e-01 6.62e-01
REACTOME PTEN REGULATION 135 1.06e-01 -8.06e-02 6.62e-01
REACTOME UREA CYCLE 9 1.08e-01 -3.09e-01 6.70e-01
REACTOME TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE 20 1.08e-01 2.08e-01 6.70e-01
REACTOME SURFACTANT METABOLISM 28 1.08e-01 1.75e-01 6.70e-01
REACTOME MIRO GTPASE CYCLE 8 1.09e-01 -3.27e-01 6.73e-01
REACTOME UCH PROTEINASES 99 1.10e-01 -9.29e-02 6.77e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR3 24 1.12e-01 1.88e-01 6.77e-01
REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE 5 1.12e-01 4.11e-01 6.77e-01
REACTOME PYRUVATE METABOLISM 29 1.12e-01 -1.70e-01 6.77e-01
REACTOME DISEASES OF GLYCOSYLATION 137 1.13e-01 -7.85e-02 6.77e-01
REACTOME COLLAGEN CHAIN TRIMERIZATION 42 1.13e-01 1.41e-01 6.77e-01
REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING 25 1.14e-01 1.83e-01 6.77e-01
REACTOME ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION 16 1.14e-01 2.28e-01 6.77e-01
REACTOME PHASE 2 PLATEAU PHASE 14 1.14e-01 2.44e-01 6.77e-01
REACTOME VITAMIN D CALCIFEROL METABOLISM 12 1.15e-01 -2.63e-01 6.77e-01
REACTOME G2 M CHECKPOINTS 162 1.15e-01 -7.18e-02 6.77e-01
REACTOME EGFR TRANSACTIVATION BY GASTRIN 9 1.15e-01 3.03e-01 6.77e-01
REACTOME RESOLUTION OF ABASIC SITES AP SITES 38 1.15e-01 -1.48e-01 6.77e-01
REACTOME SYNTHESIS OF 5 EICOSATETRAENOIC ACIDS 9 1.16e-01 3.03e-01 6.77e-01
REACTOME PI5P REGULATES TP53 ACETYLATION 9 1.18e-01 -3.01e-01 6.87e-01
REACTOME TRANSPORT OF FATTY ACIDS 8 1.19e-01 3.18e-01 6.93e-01
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION 361 1.20e-01 -4.76e-02 6.98e-01
REACTOME INTERLEUKIN 36 PATHWAY 7 1.21e-01 3.38e-01 6.98e-01
REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX 21 1.21e-01 1.95e-01 6.98e-01
REACTOME OPIOID SIGNALLING 89 1.22e-01 9.48e-02 7.01e-01
REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS 12 1.23e-01 2.57e-01 7.03e-01
REACTOME COSTIMULATION BY THE CD28 FAMILY 64 1.25e-01 -1.11e-01 7.07e-01
REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING 30 1.25e-01 1.62e-01 7.07e-01
REACTOME HIV TRANSCRIPTION ELONGATION 42 1.25e-01 -1.37e-01 7.07e-01
REACTOME SHC1 EVENTS IN EGFR SIGNALING 14 1.25e-01 2.37e-01 7.07e-01
REACTOME SHC MEDIATED CASCADE FGFR3 17 1.26e-01 2.14e-01 7.08e-01
REACTOME RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION 6 1.27e-01 -3.60e-01 7.11e-01
REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES 91 1.27e-01 -9.25e-02 7.11e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS 12 1.30e-01 2.52e-01 7.23e-01
REACTOME CHREBP ACTIVATES METABOLIC GENE EXPRESSION 8 1.31e-01 -3.09e-01 7.23e-01
REACTOME PI 3K CASCADE FGFR1 21 1.32e-01 1.90e-01 7.23e-01
REACTOME ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES 59 1.32e-01 1.13e-01 7.23e-01
REACTOME SIGNALLING TO ERKS 34 1.32e-01 1.49e-01 7.23e-01
REACTOME REGULATION OF FZD BY UBIQUITINATION 21 1.32e-01 1.90e-01 7.23e-01
REACTOME FRS MEDIATED FGFR2 SIGNALING 24 1.33e-01 1.77e-01 7.23e-01
REACTOME PECAM1 INTERACTIONS 12 1.33e-01 -2.50e-01 7.25e-01
REACTOME DISSOLUTION OF FIBRIN CLOT 13 1.34e-01 2.40e-01 7.25e-01
REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY 26 1.34e-01 -1.70e-01 7.25e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3 11 1.36e-01 2.59e-01 7.28e-01
REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY 25 1.36e-01 -1.72e-01 7.28e-01
REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES 39 1.37e-01 1.38e-01 7.28e-01
REACTOME INTRAFLAGELLAR TRANSPORT 50 1.37e-01 -1.22e-01 7.28e-01
REACTOME DEADENYLATION OF MRNA 25 1.39e-01 -1.71e-01 7.28e-01
REACTOME DUAL INCISION IN TC NER 63 1.39e-01 -1.08e-01 7.28e-01
REACTOME RETROGRADE NEUROTROPHIN SIGNALLING 14 1.39e-01 2.28e-01 7.28e-01
REACTOME METABOLISM OF STEROIDS 150 1.40e-01 -6.99e-02 7.28e-01
REACTOME FATTY ACIDS 15 1.40e-01 2.20e-01 7.28e-01
REACTOME MET RECEPTOR RECYCLING 10 1.40e-01 2.69e-01 7.28e-01
REACTOME SYNTHESIS OF PG 8 1.40e-01 3.01e-01 7.28e-01
REACTOME DNA STRAND ELONGATION 31 1.40e-01 -1.53e-01 7.28e-01
REACTOME DERMATAN SULFATE BIOSYNTHESIS 10 1.40e-01 2.69e-01 7.28e-01
REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS 8 1.42e-01 -3.00e-01 7.30e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER 28 1.42e-01 -1.60e-01 7.30e-01
REACTOME SIGNALING BY FLT3 FUSION PROTEINS 19 1.42e-01 1.94e-01 7.30e-01
REACTOME CARGO CONCENTRATION IN THE ER 32 1.43e-01 1.50e-01 7.30e-01
REACTOME UPTAKE OF DIETARY COBALAMINS INTO ENTEROCYTES 9 1.43e-01 -2.82e-01 7.30e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES 10 1.44e-01 2.67e-01 7.33e-01
REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION 19 1.45e-01 1.93e-01 7.35e-01
REACTOME DEATH RECEPTOR SIGNALING 143 1.46e-01 -7.04e-02 7.37e-01
REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION 59 1.47e-01 1.09e-01 7.37e-01
REACTOME METHIONINE SALVAGE PATHWAY 6 1.47e-01 -3.42e-01 7.37e-01
REACTOME REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION 9 1.48e-01 -2.79e-01 7.37e-01
REACTOME AMYLOID FIBER FORMATION 102 1.49e-01 -8.28e-02 7.37e-01
REACTOME SIGNALING BY FGFR1 49 1.49e-01 1.19e-01 7.37e-01
REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS 113 1.49e-01 -7.86e-02 7.37e-01
REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK 111 1.49e-01 7.92e-02 7.37e-01
REACTOME EUKARYOTIC TRANSLATION ELONGATION 87 1.50e-01 8.93e-02 7.37e-01
REACTOME G PROTEIN MEDIATED EVENTS 53 1.51e-01 1.14e-01 7.37e-01
REACTOME IRS MEDIATED SIGNALLING 47 1.51e-01 1.21e-01 7.37e-01
REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM 78 1.52e-01 -9.39e-02 7.37e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS 121 1.52e-01 -7.55e-02 7.37e-01
REACTOME EGFR DOWNREGULATION 30 1.52e-01 1.51e-01 7.37e-01
REACTOME NEGATIVE REGULATION OF MET ACTIVITY 20 1.52e-01 1.85e-01 7.37e-01
REACTOME GLUTAMATE AND GLUTAMINE METABOLISM 13 1.55e-01 -2.28e-01 7.48e-01
REACTOME ERK MAPK TARGETS 20 1.58e-01 1.82e-01 7.60e-01
REACTOME BIOSYNTHESIS OF MARESINS 8 1.59e-01 -2.88e-01 7.60e-01
REACTOME RAF INDEPENDENT MAPK1 3 ACTIVATION 22 1.59e-01 -1.73e-01 7.60e-01
REACTOME RNA POLYMERASE II TRANSCRIPTION 1336 1.60e-01 -2.29e-02 7.60e-01
REACTOME RHO GTPASE EFFECTORS 305 1.60e-01 -4.68e-02 7.60e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS 9 1.60e-01 -2.70e-01 7.60e-01
REACTOME G2 PHASE 5 1.61e-01 3.62e-01 7.61e-01
REACTOME SUMO IS CONJUGATED TO E1 UBA2 SAE1 5 1.63e-01 -3.61e-01 7.67e-01
REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R 52 1.63e-01 1.12e-01 7.69e-01
REACTOME TRANSCRIPTION OF THE HIV GENOME 66 1.65e-01 -9.89e-02 7.70e-01
REACTOME SCAVENGING BY CLASS A RECEPTORS 19 1.65e-01 1.84e-01 7.70e-01
REACTOME VLDL ASSEMBLY 5 1.66e-01 3.58e-01 7.70e-01
REACTOME SIGNALING BY FLT3 ITD AND TKD MUTANTS 16 1.66e-01 2.00e-01 7.70e-01
REACTOME TRANSPORT OF ORGANIC ANIONS 10 1.67e-01 2.52e-01 7.70e-01
REACTOME INTERLEUKIN 1 PROCESSING 9 1.67e-01 2.66e-01 7.70e-01
REACTOME MITOTIC PROPHASE 134 1.68e-01 -6.90e-02 7.70e-01
REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3 679 1.68e-01 -3.10e-02 7.70e-01
REACTOME DOWNSTREAM SIGNAL TRANSDUCTION 29 1.69e-01 1.48e-01 7.70e-01
REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT 222 1.69e-01 -5.36e-02 7.70e-01
REACTOME NUCLEOTIDE SALVAGE 21 1.69e-01 1.73e-01 7.70e-01
REACTOME CHAPERONE MEDIATED AUTOPHAGY 20 1.70e-01 -1.77e-01 7.70e-01
REACTOME HUR ELAVL1 BINDS AND STABILIZES MRNA 8 1.70e-01 2.80e-01 7.70e-01
REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND 21 1.71e-01 1.73e-01 7.70e-01
REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF 53 1.71e-01 -1.09e-01 7.70e-01
REACTOME TRANS GOLGI NETWORK VESICLE BUDDING 67 1.73e-01 9.63e-02 7.70e-01
REACTOME TRANSCRIPTIONAL REGULATION BY E2F6 32 1.73e-01 -1.39e-01 7.70e-01
REACTOME ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS 87 1.74e-01 8.44e-02 7.70e-01
REACTOME TELOMERE C STRAND SYNTHESIS INITIATION 12 1.74e-01 -2.27e-01 7.70e-01
REACTOME COMPLEX I BIOGENESIS 49 1.74e-01 -1.12e-01 7.70e-01
REACTOME INSULIN RECEPTOR SIGNALLING CASCADE 53 1.75e-01 1.08e-01 7.70e-01
REACTOME DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE 17 1.75e-01 1.90e-01 7.70e-01
REACTOME DEFECTIVE CHST14 CAUSES EDS MUSCULOCONTRACTURAL TYPE 7 1.76e-01 2.96e-01 7.70e-01
REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE 22 1.76e-01 1.67e-01 7.70e-01
REACTOME SHC MEDIATED CASCADE FGFR1 21 1.76e-01 1.71e-01 7.70e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR4 14 1.76e-01 2.09e-01 7.70e-01
REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING 33 1.77e-01 1.36e-01 7.71e-01
REACTOME DAP12 INTERACTIONS 37 1.77e-01 1.28e-01 7.71e-01
REACTOME MATURATION OF PROTEIN 3A 9 1.78e-01 2.59e-01 7.72e-01
REACTOME ORGANIC ANION TRANSPORTERS 10 1.79e-01 2.46e-01 7.72e-01
REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION 10 1.79e-01 -2.46e-01 7.72e-01
REACTOME BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA 5 1.79e-01 3.47e-01 7.72e-01
REACTOME RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX 29 1.81e-01 -1.44e-01 7.77e-01
REACTOME DNA DAMAGE BYPASS 47 1.82e-01 -1.13e-01 7.79e-01
REACTOME CALNEXIN CALRETICULIN CYCLE 26 1.83e-01 1.51e-01 7.79e-01
REACTOME PYRIMIDINE CATABOLISM 12 1.83e-01 2.22e-01 7.79e-01
REACTOME CELL CELL JUNCTION ORGANIZATION 64 1.85e-01 9.59e-02 7.79e-01
REACTOME SYNTHESIS OF DOLICHYL PHOSPHATE 6 1.87e-01 -3.11e-01 7.79e-01
REACTOME UBIQUINOL BIOSYNTHESIS 8 1.87e-01 2.70e-01 7.79e-01
REACTOME FRS MEDIATED FGFR3 SIGNALING 19 1.87e-01 1.75e-01 7.79e-01
REACTOME RHOT1 GTPASE CYCLE 5 1.87e-01 -3.41e-01 7.79e-01
REACTOME REGULATION OF SIGNALING BY NODAL 9 1.87e-01 2.54e-01 7.79e-01
REACTOME L1CAM INTERACTIONS 112 1.88e-01 7.20e-02 7.79e-01
REACTOME SUMOYLATION OF DNA METHYLATION PROTEINS 16 1.88e-01 -1.90e-01 7.79e-01
REACTOME COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES 65 1.88e-01 9.44e-02 7.79e-01
REACTOME RUNX3 REGULATES BCL2L11 BIM TRANSCRIPTION 5 1.88e-01 -3.40e-01 7.79e-01
REACTOME REGULATION OF PTEN STABILITY AND ACTIVITY 67 1.89e-01 -9.28e-02 7.79e-01
REACTOME ENOS ACTIVATION 11 1.89e-01 -2.29e-01 7.79e-01
REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM 20 1.90e-01 1.69e-01 7.79e-01
REACTOME INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS 37 1.90e-01 -1.25e-01 7.79e-01
REACTOME SHC1 EVENTS IN ERBB2 SIGNALING 22 1.90e-01 1.61e-01 7.79e-01
REACTOME SIGNALING BY WNT 318 1.90e-01 -4.27e-02 7.80e-01
REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK 17 1.93e-01 1.83e-01 7.81e-01
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE 105 1.93e-01 7.36e-02 7.81e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE 8 1.93e-01 -2.66e-01 7.81e-01
REACTOME MET ACTIVATES PI3K AKT SIGNALING 6 1.94e-01 3.06e-01 7.81e-01
REACTOME SELENOAMINO ACID METABOLISM 108 1.94e-01 7.23e-02 7.81e-01
REACTOME INTERLEUKIN 17 SIGNALING 66 1.94e-01 9.24e-02 7.81e-01
REACTOME HYDROLYSIS OF LPC 9 1.95e-01 -2.50e-01 7.81e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES 12 1.95e-01 2.16e-01 7.81e-01
REACTOME FASL CD95L SIGNALING 5 1.95e-01 3.35e-01 7.81e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION 27 1.96e-01 1.44e-01 7.83e-01
REACTOME CROSSLINKING OF COLLAGEN FIBRILS 16 1.97e-01 1.86e-01 7.85e-01
REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE 66 1.98e-01 -9.16e-02 7.87e-01
REACTOME INTRINSIC PATHWAY FOR APOPTOSIS 54 1.99e-01 -1.01e-01 7.87e-01
REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS 14 1.99e-01 1.98e-01 7.88e-01
REACTOME FATTY ACYL COA BIOSYNTHESIS 36 2.01e-01 1.23e-01 7.92e-01
REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION 6 2.02e-01 -3.01e-01 7.92e-01
REACTOME INTERLEUKIN 9 SIGNALING 7 2.02e-01 -2.78e-01 7.92e-01
REACTOME CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND 16 2.03e-01 1.84e-01 7.92e-01
REACTOME SIGNALING BY NUCLEAR RECEPTORS 283 2.04e-01 -4.39e-02 7.92e-01
REACTOME SIGNALING BY FGFR3 39 2.05e-01 1.17e-01 7.92e-01
REACTOME PHENYLALANINE METABOLISM 6 2.06e-01 -2.98e-01 7.92e-01
REACTOME ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA 5 2.06e-01 -3.27e-01 7.92e-01
REACTOME TRAIL SIGNALING 8 2.06e-01 2.58e-01 7.92e-01
REACTOME ANTIMICROBIAL PEPTIDES 76 2.07e-01 8.37e-02 7.92e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS 15 2.07e-01 1.88e-01 7.92e-01
REACTOME FBXW7 MUTANTS AND NOTCH1 IN CANCER 5 2.07e-01 3.26e-01 7.92e-01
REACTOME CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER 25 2.08e-01 -1.46e-01 7.92e-01
REACTOME RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK 47 2.08e-01 -1.06e-01 7.92e-01
REACTOME METALLOPROTEASE DUBS 36 2.09e-01 -1.21e-01 7.92e-01
REACTOME VXPX CARGO TARGETING TO CILIUM 20 2.10e-01 -1.62e-01 7.92e-01
REACTOME PROTEIN METHYLATION 17 2.10e-01 -1.76e-01 7.92e-01
REACTOME CELLULAR RESPONSES TO STIMULI 779 2.10e-01 -2.64e-02 7.92e-01
REACTOME RA BIOSYNTHESIS PATHWAY 22 2.10e-01 1.54e-01 7.92e-01
REACTOME ACTIVATION OF NIMA KINASES NEK9 NEK6 NEK7 7 2.11e-01 2.73e-01 7.92e-01
REACTOME MISMATCH REPAIR 15 2.11e-01 -1.86e-01 7.92e-01
REACTOME CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY 25 2.12e-01 1.44e-01 7.92e-01
REACTOME NONCANONICAL ACTIVATION OF NOTCH3 8 2.12e-01 -2.55e-01 7.92e-01
REACTOME RRNA MODIFICATION IN THE MITOCHONDRION 6 2.12e-01 -2.94e-01 7.92e-01
REACTOME SEMAPHORIN INTERACTIONS 61 2.13e-01 9.23e-02 7.92e-01
REACTOME SIGNALING BY PDGF 57 2.14e-01 9.52e-02 7.92e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES 61 2.14e-01 -9.20e-02 7.92e-01
REACTOME CIRCADIAN CLOCK 68 2.14e-01 8.71e-02 7.92e-01
REACTOME CA DEPENDENT EVENTS 36 2.15e-01 1.20e-01 7.92e-01
REACTOME RELAXIN RECEPTORS 8 2.15e-01 2.53e-01 7.92e-01
REACTOME MELANIN BIOSYNTHESIS 5 2.16e-01 3.19e-01 7.92e-01
REACTOME CLATHRIN MEDIATED ENDOCYTOSIS 139 2.17e-01 6.07e-02 7.92e-01
REACTOME POTENTIAL THERAPEUTICS FOR SARS 92 2.17e-01 -7.44e-02 7.92e-01
REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI 17 2.18e-01 -1.73e-01 7.92e-01
REACTOME DISEASES OF METABOLISM 237 2.18e-01 -4.65e-02 7.92e-01
REACTOME REGULATION OF NF KAPPA B SIGNALING 17 2.18e-01 -1.72e-01 7.92e-01
REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS 13 2.19e-01 1.97e-01 7.92e-01
REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS 9 2.19e-01 -2.37e-01 7.92e-01
REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP 41 2.19e-01 -1.11e-01 7.92e-01
REACTOME DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A 5 2.20e-01 -3.17e-01 7.92e-01
REACTOME FGFR2C LIGAND BINDING AND ACTIVATION 12 2.20e-01 2.05e-01 7.92e-01
REACTOME LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME 11 2.22e-01 -2.13e-01 7.93e-01
REACTOME SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS 12 2.23e-01 2.03e-01 7.93e-01
REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN 37 2.23e-01 -1.16e-01 7.93e-01
REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS 6 2.23e-01 2.87e-01 7.93e-01
REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES 80 2.23e-01 -7.87e-02 7.93e-01
REACTOME NUCLEAR IMPORT OF REV PROTEIN 34 2.24e-01 -1.20e-01 7.93e-01
REACTOME SIGNALING BY ROBO RECEPTORS 206 2.25e-01 4.91e-02 7.93e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES 11 2.25e-01 2.11e-01 7.93e-01
REACTOME MATURATION OF SARS COV 2 NUCLEOPROTEIN 15 2.26e-01 -1.81e-01 7.93e-01
REACTOME N GLYCAN ANTENNAE ELONGATION 15 2.26e-01 1.81e-01 7.93e-01
REACTOME INFECTIOUS DISEASE 910 2.28e-01 -2.36e-02 7.93e-01
REACTOME OPSINS 7 2.28e-01 -2.63e-01 7.93e-01
REACTOME ACTIVATION OF RAS IN B CELLS 5 2.29e-01 -3.11e-01 7.93e-01
REACTOME RAB REGULATION OF TRAFFICKING 110 2.29e-01 -6.63e-02 7.93e-01
REACTOME INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION 21 2.30e-01 -1.51e-01 7.93e-01
REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE 17 2.30e-01 -1.68e-01 7.93e-01
REACTOME METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES 33 2.30e-01 -1.21e-01 7.93e-01
REACTOME MITOTIC G2 G2 M PHASES 194 2.31e-01 -4.98e-02 7.93e-01
REACTOME CGMP EFFECTS 16 2.32e-01 1.73e-01 7.93e-01
REACTOME STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS 10 2.32e-01 2.18e-01 7.93e-01
REACTOME PHASE 1 INACTIVATION OF FAST NA CHANNELS 6 2.33e-01 2.81e-01 7.93e-01
REACTOME NONSENSE MEDIATED DECAY NMD 107 2.33e-01 6.67e-02 7.93e-01
REACTOME INTERLEUKIN 6 FAMILY SIGNALING 24 2.33e-01 -1.41e-01 7.93e-01
REACTOME SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX 15 2.34e-01 -1.78e-01 7.93e-01
REACTOME RHO GTPASES ACTIVATE IQGAPS 31 2.35e-01 1.23e-01 7.93e-01
REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES 29 2.35e-01 1.27e-01 7.93e-01
REACTOME ION HOMEOSTASIS 52 2.37e-01 9.48e-02 7.93e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING 6 2.37e-01 -2.79e-01 7.93e-01
REACTOME CD28 DEPENDENT PI3K AKT SIGNALING 22 2.37e-01 -1.46e-01 7.93e-01
REACTOME TRANSCRIPTIONAL REGULATION BY VENTX 41 2.37e-01 -1.07e-01 7.93e-01
REACTOME GOLGI TO ER RETROGRADE TRANSPORT 132 2.37e-01 -5.96e-02 7.93e-01
REACTOME DUAL INCISION IN GG NER 39 2.38e-01 -1.09e-01 7.93e-01
REACTOME PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR 21 2.38e-01 -1.49e-01 7.93e-01
REACTOME NEF MEDIATED CD8 DOWN REGULATION 7 2.38e-01 -2.58e-01 7.93e-01
REACTOME SUMO IS PROTEOLYTICALLY PROCESSED 6 2.38e-01 -2.78e-01 7.93e-01
REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC 198 2.38e-01 -4.86e-02 7.93e-01
REACTOME RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION 8 2.39e-01 -2.40e-01 7.93e-01
REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION 26 2.39e-01 1.33e-01 7.93e-01
REACTOME FRS MEDIATED FGFR1 SIGNALING 23 2.39e-01 1.42e-01 7.93e-01
REACTOME ALPHA DEFENSINS 6 2.39e-01 2.77e-01 7.93e-01
REACTOME FLT3 SIGNALING IN DISEASE 28 2.40e-01 1.28e-01 7.94e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL 14 2.44e-01 -1.80e-01 7.98e-01
REACTOME TELOMERE EXTENSION BY TELOMERASE 22 2.44e-01 -1.44e-01 7.98e-01
REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING 28 2.45e-01 1.27e-01 7.98e-01
REACTOME RHOBTB3 ATPASE CYCLE 8 2.46e-01 -2.37e-01 7.98e-01
REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION 8 2.46e-01 2.37e-01 7.98e-01
REACTOME TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE 39 2.47e-01 -1.07e-01 7.98e-01
REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE 30 2.47e-01 1.22e-01 7.98e-01
REACTOME HDMS DEMETHYLATE HISTONES 40 2.47e-01 -1.06e-01 7.98e-01
REACTOME ARMS MEDIATED ACTIVATION 7 2.47e-01 2.53e-01 7.98e-01
REACTOME SIGNALING BY NTRK2 TRKB 25 2.48e-01 1.34e-01 7.98e-01
REACTOME ACYL CHAIN REMODELLING OF PG 18 2.48e-01 -1.57e-01 7.98e-01
REACTOME CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION 24 2.48e-01 1.36e-01 7.98e-01
REACTOME SIGNALING BY LEPTIN 11 2.49e-01 -2.01e-01 7.98e-01
REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION 23 2.49e-01 1.39e-01 7.98e-01
REACTOME MITOCHONDRIAL CALCIUM ION TRANSPORT 23 2.50e-01 -1.39e-01 7.98e-01
REACTOME RUNX3 REGULATES CDKN1A TRANSCRIPTION 7 2.51e-01 -2.51e-01 7.98e-01
REACTOME RAC3 GTPASE CYCLE 85 2.51e-01 7.20e-02 7.98e-01
REACTOME REGULATION OF BETA CELL DEVELOPMENT 41 2.52e-01 1.03e-01 7.98e-01
REACTOME NECTIN NECL TRANS HETERODIMERIZATION 7 2.52e-01 2.50e-01 7.98e-01
REACTOME PI3K AKT ACTIVATION 9 2.52e-01 2.20e-01 7.98e-01
REACTOME S PHASE 159 2.52e-01 -5.26e-02 7.98e-01
REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR 79 2.53e-01 -7.44e-02 7.98e-01
REACTOME POLYMERASE SWITCHING 13 2.53e-01 -1.83e-01 7.98e-01
REACTOME IKBA VARIANT LEADS TO EDA ID 6 2.54e-01 -2.69e-01 7.98e-01
REACTOME TAK1 DEPENDENT IKK AND NF KAPPA B ACTIVATION 41 2.54e-01 -1.03e-01 7.98e-01
REACTOME GLYCOSAMINOGLYCAN METABOLISM 118 2.55e-01 6.07e-02 8.00e-01
REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS 23 2.56e-01 -1.37e-01 8.03e-01
REACTOME IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS 17 2.57e-01 -1.59e-01 8.04e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG 7 2.60e-01 -2.46e-01 8.09e-01
REACTOME NEF MEDIATED CD4 DOWN REGULATION 9 2.60e-01 -2.17e-01 8.09e-01
REACTOME MITOTIC SPINDLE CHECKPOINT 109 2.61e-01 -6.24e-02 8.09e-01
REACTOME VIRAL MESSENGER RNA SYNTHESIS 44 2.61e-01 -9.79e-02 8.09e-01
REACTOME NCAM1 INTERACTIONS 41 2.61e-01 1.01e-01 8.09e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH PI3K 6 2.65e-01 2.63e-01 8.21e-01
REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION 13 2.67e-01 1.78e-01 8.25e-01
REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN 32 2.68e-01 -1.13e-01 8.25e-01
REACTOME CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE 49 2.68e-01 -9.14e-02 8.25e-01
REACTOME REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA 15 2.69e-01 -1.65e-01 8.25e-01
REACTOME SYNTHESIS OF DNA 119 2.70e-01 -5.86e-02 8.26e-01
REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS 11 2.70e-01 -1.92e-01 8.26e-01
REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION 20 2.71e-01 1.42e-01 8.27e-01
REACTOME RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS 5 2.72e-01 -2.84e-01 8.27e-01
REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN 15 2.72e-01 1.64e-01 8.27e-01
REACTOME PEXOPHAGY 11 2.72e-01 -1.91e-01 8.27e-01
REACTOME THYROXINE BIOSYNTHESIS 10 2.73e-01 2.00e-01 8.27e-01
REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES 34 2.76e-01 1.08e-01 8.33e-01
REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE 9 2.76e-01 -2.10e-01 8.33e-01
REACTOME MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS 13 2.77e-01 1.74e-01 8.33e-01
REACTOME ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT 23 2.78e-01 -1.31e-01 8.33e-01
REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS 11 2.78e-01 -1.89e-01 8.33e-01
REACTOME LATE SARS COV 2 INFECTION EVENTS 67 2.79e-01 -7.65e-02 8.33e-01
REACTOME NEUROTOXICITY OF CLOSTRIDIUM TOXINS 10 2.79e-01 1.98e-01 8.33e-01
REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS 23 2.80e-01 1.30e-01 8.33e-01
REACTOME SUMOYLATION OF UBIQUITINYLATION PROTEINS 39 2.80e-01 -9.99e-02 8.33e-01
REACTOME IRAK4 DEFICIENCY TLR2 4 17 2.81e-01 1.51e-01 8.33e-01
REACTOME PINK1 PRKN MEDIATED MITOPHAGY 22 2.82e-01 -1.33e-01 8.33e-01
REACTOME PI3K AKT SIGNALING IN CANCER 103 2.83e-01 6.13e-02 8.33e-01
REACTOME DEFECTIVE CHST6 CAUSES MCDC1 8 2.83e-01 -2.19e-01 8.33e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2 17 2.83e-01 1.50e-01 8.33e-01
REACTOME BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS 10 2.84e-01 -1.96e-01 8.33e-01
REACTOME REGULATED NECROSIS 57 2.84e-01 8.20e-02 8.33e-01
REACTOME FORMATION OF TC NER PRE INCISION COMPLEX 51 2.84e-01 -8.67e-02 8.33e-01
REACTOME DIGESTION AND ABSORPTION 22 2.85e-01 -1.32e-01 8.33e-01
REACTOME DAG AND IP3 SIGNALING 40 2.85e-01 9.76e-02 8.33e-01
REACTOME METABOLISM OF LIPIDS 709 2.85e-01 -2.36e-02 8.33e-01
REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING 32 2.85e-01 1.09e-01 8.33e-01
REACTOME SYNTHESIS OF DIPHTHAMIDE EEF2 8 2.86e-01 -2.18e-01 8.34e-01
REACTOME NEF AND SIGNAL TRANSDUCTION 8 2.87e-01 -2.17e-01 8.35e-01
REACTOME INTERLEUKIN 18 SIGNALING 8 2.89e-01 2.17e-01 8.37e-01
REACTOME SEROTONIN RECEPTORS 11 2.90e-01 1.84e-01 8.38e-01
REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT 15 2.90e-01 -1.58e-01 8.38e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES 15 2.91e-01 -1.57e-01 8.38e-01
REACTOME TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS 82 2.92e-01 -6.74e-02 8.38e-01
REACTOME LAMININ INTERACTIONS 28 2.94e-01 -1.15e-01 8.38e-01
REACTOME METABOLISM OF FOLATE AND PTERINES 17 2.94e-01 -1.47e-01 8.38e-01
REACTOME SIGNALING BY INSULIN RECEPTOR 80 2.94e-01 6.79e-02 8.38e-01
REACTOME TRNA MODIFICATION IN THE MITOCHONDRION 8 2.95e-01 -2.14e-01 8.38e-01
REACTOME RAC2 GTPASE CYCLE 81 2.95e-01 6.73e-02 8.38e-01
REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB 5 2.96e-01 2.70e-01 8.38e-01
REACTOME LGI ADAM INTERACTIONS 14 2.96e-01 1.61e-01 8.38e-01
REACTOME ACTIVATION OF PPARGC1A PGC 1ALPHA BY PHOSPHORYLATION 10 2.96e-01 1.91e-01 8.38e-01
REACTOME PI METABOLISM 79 2.96e-01 -6.80e-02 8.38e-01
REACTOME SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER 15 2.96e-01 1.56e-01 8.38e-01
REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES 101 2.96e-01 6.01e-02 8.38e-01
REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM 45 2.97e-01 8.98e-02 8.38e-01
REACTOME RAB GERANYLGERANYLATION 57 2.98e-01 7.97e-02 8.39e-01
REACTOME MTOR SIGNALLING 40 2.99e-01 -9.50e-02 8.40e-01
REACTOME TRANSLATION 278 3.01e-01 3.60e-02 8.43e-01
REACTOME SIGNALING BY MET 78 3.01e-01 6.77e-02 8.43e-01
REACTOME REGULATION BY C FLIP 11 3.01e-01 1.80e-01 8.43e-01
REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS 81 3.02e-01 -6.64e-02 8.43e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL 24 3.02e-01 1.22e-01 8.43e-01
REACTOME SELECTIVE AUTOPHAGY 79 3.05e-01 -6.67e-02 8.46e-01
REACTOME METABOLISM OF FAT SOLUBLE VITAMINS 46 3.05e-01 8.74e-02 8.46e-01
REACTOME COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM 21 3.06e-01 -1.29e-01 8.46e-01
REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER 49 3.06e-01 -8.45e-02 8.46e-01
REACTOME FORMATION OF LATERAL PLATE MESODERM 5 3.06e-01 2.64e-01 8.46e-01
REACTOME RESPIRATORY ELECTRON TRANSPORT 90 3.08e-01 -6.21e-02 8.47e-01
REACTOME SIGNALING BY THE B CELL RECEPTOR BCR 106 3.08e-01 -5.73e-02 8.47e-01
REACTOME GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION 7 3.09e-01 2.22e-01 8.47e-01
REACTOME HYALURONAN UPTAKE AND DEGRADATION 12 3.09e-01 1.70e-01 8.47e-01
REACTOME MUCOPOLYSACCHARIDOSES 10 3.09e-01 -1.86e-01 8.47e-01
REACTOME HDL REMODELING 10 3.09e-01 1.86e-01 8.47e-01
REACTOME PP2A MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS 6 3.10e-01 2.39e-01 8.47e-01
REACTOME ACTIVATION OF C3 AND C5 6 3.12e-01 -2.38e-01 8.50e-01
REACTOME REGULATION OF TP53 ACTIVITY 156 3.13e-01 -4.68e-02 8.50e-01
REACTOME VLDL CLEARANCE 6 3.14e-01 2.37e-01 8.50e-01
REACTOME CAMK IV MEDIATED PHOSPHORYLATION OF CREB 10 3.14e-01 -1.84e-01 8.50e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX 91 3.15e-01 -6.10e-02 8.50e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING 5 3.16e-01 -2.59e-01 8.50e-01
REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES 77 3.16e-01 6.61e-02 8.50e-01
REACTOME COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING 32 3.16e-01 1.02e-01 8.50e-01
REACTOME NETRIN 1 SIGNALING 49 3.17e-01 8.27e-02 8.50e-01
REACTOME ACTIVATION OF TRKA RECEPTORS 6 3.17e-01 2.36e-01 8.50e-01
REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS 23 3.17e-01 1.20e-01 8.50e-01
REACTOME RHOV GTPASE CYCLE 36 3.18e-01 -9.62e-02 8.50e-01
REACTOME SENSORY PERCEPTION OF SALTY TASTE 6 3.19e-01 2.35e-01 8.50e-01
REACTOME P2Y RECEPTORS 9 3.19e-01 1.92e-01 8.50e-01
REACTOME INTERFERON GAMMA SIGNALING 88 3.19e-01 6.14e-02 8.50e-01
REACTOME DEX H BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION 7 3.20e-01 -2.17e-01 8.50e-01
REACTOME DEFECTIVE F9 ACTIVATION 5 3.20e-01 2.57e-01 8.50e-01
REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE 35 3.21e-01 9.70e-02 8.50e-01
REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX 32 3.22e-01 -1.01e-01 8.50e-01
REACTOME UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION 19 3.22e-01 1.31e-01 8.50e-01
REACTOME CHONDROITIN SULFATE BIOSYNTHESIS 18 3.23e-01 1.35e-01 8.50e-01
REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS 66 3.24e-01 -7.03e-02 8.50e-01
REACTOME NEUROFASCIN INTERACTIONS 6 3.24e-01 2.32e-01 8.50e-01
REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION 62 3.24e-01 -7.24e-02 8.50e-01
REACTOME NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 19 3.24e-01 -1.31e-01 8.50e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE GIP 12 3.25e-01 1.64e-01 8.50e-01
REACTOME CREATION OF C4 AND C2 ACTIVATORS 14 3.25e-01 1.52e-01 8.50e-01
REACTOME SIGNALING BY PDGFR IN DISEASE 20 3.26e-01 1.27e-01 8.50e-01
REACTOME FGFR1 LIGAND BINDING AND ACTIVATION 15 3.27e-01 1.46e-01 8.50e-01
REACTOME GASTRULATION 49 3.27e-01 8.10e-02 8.50e-01
REACTOME CONJUGATION OF BENZOATE WITH GLYCINE 6 3.27e-01 2.31e-01 8.50e-01
REACTOME PTK6 EXPRESSION 5 3.28e-01 2.53e-01 8.50e-01
REACTOME RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA 7 3.29e-01 -2.13e-01 8.50e-01
REACTOME GPER1 SIGNALING 45 3.29e-01 8.41e-02 8.50e-01
REACTOME P38MAPK EVENTS 13 3.29e-01 1.56e-01 8.50e-01
REACTOME GLUTATHIONE CONJUGATION 33 3.30e-01 -9.80e-02 8.50e-01
REACTOME ACYL CHAIN REMODELLING OF PC 27 3.30e-01 -1.08e-01 8.50e-01
REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING 89 3.31e-01 -5.96e-02 8.50e-01
REACTOME SNRNP ASSEMBLY 53 3.32e-01 -7.70e-02 8.50e-01
REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS 51 3.33e-01 7.84e-02 8.50e-01
REACTOME CS DS DEGRADATION 12 3.33e-01 1.61e-01 8.50e-01
REACTOME PKA ACTIVATION IN GLUCAGON SIGNALLING 17 3.33e-01 1.36e-01 8.50e-01
REACTOME CROSS PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS PHAGOSOMES 6 3.34e-01 -2.28e-01 8.50e-01
REACTOME DISEASES OF MISMATCH REPAIR MMR 5 3.34e-01 2.49e-01 8.50e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL 15 3.35e-01 1.44e-01 8.50e-01
REACTOME DOWNREGULATION OF ERBB4 SIGNALING 9 3.35e-01 1.85e-01 8.50e-01
REACTOME COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC 52 3.36e-01 -7.71e-02 8.50e-01
REACTOME MITOTIC PROMETAPHASE 194 3.37e-01 -3.99e-02 8.50e-01
REACTOME NOTCH HLH TRANSCRIPTION PATHWAY 24 3.38e-01 -1.13e-01 8.50e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM 38 3.39e-01 8.97e-02 8.50e-01
REACTOME TRANSCRIPTIONAL REGULATION BY TP53 351 3.39e-01 -2.97e-02 8.50e-01
REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES 353 3.39e-01 2.96e-02 8.50e-01
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS 161 3.39e-01 4.36e-02 8.50e-01
REACTOME PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING 11 3.40e-01 1.66e-01 8.50e-01
REACTOME AMINE LIGAND BINDING RECEPTORS 40 3.40e-01 8.72e-02 8.50e-01
REACTOME BASIGIN INTERACTIONS 24 3.40e-01 1.12e-01 8.50e-01
REACTOME NEUREXINS AND NEUROLIGINS 51 3.40e-01 7.72e-02 8.50e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH RAS 8 3.41e-01 1.94e-01 8.50e-01
REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE 15 3.42e-01 -1.42e-01 8.50e-01
REACTOME LATE ENDOSOMAL MICROAUTOPHAGY 33 3.42e-01 -9.55e-02 8.50e-01
REACTOME RRNA PROCESSING IN THE MITOCHONDRION 9 3.43e-01 -1.82e-01 8.50e-01
REACTOME FORMATION OF XYLULOSE 5 PHOSPHATE 5 3.44e-01 2.44e-01 8.50e-01
REACTOME MET ACTIVATES PTPN11 5 3.44e-01 2.44e-01 8.50e-01
REACTOME ER QUALITY CONTROL COMPARTMENT ERQC 21 3.44e-01 1.19e-01 8.50e-01
REACTOME ADRENOCEPTORS 9 3.45e-01 1.82e-01 8.50e-01
REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS 35 3.45e-01 9.22e-02 8.50e-01
REACTOME ADAPTIVE IMMUNE SYSTEM 729 3.46e-01 -2.05e-02 8.52e-01
REACTOME CA2 ACTIVATED K CHANNELS 9 3.48e-01 1.81e-01 8.54e-01
REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS 33 3.49e-01 -9.43e-02 8.54e-01
REACTOME RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES TREGS 9 3.50e-01 1.80e-01 8.54e-01
REACTOME TRIGLYCERIDE CATABOLISM 23 3.50e-01 1.13e-01 8.54e-01
REACTOME LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX 5 3.51e-01 -2.41e-01 8.54e-01
REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE 16 3.52e-01 -1.34e-01 8.54e-01
REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX 15 3.52e-01 1.39e-01 8.54e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN 21 3.52e-01 -1.17e-01 8.54e-01
REACTOME CHYLOMICRON REMODELING 10 3.52e-01 -1.70e-01 8.54e-01
REACTOME CONDENSATION OF PROMETAPHASE CHROMOSOMES 11 3.53e-01 1.62e-01 8.54e-01
REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX 134 3.54e-01 4.64e-02 8.55e-01
REACTOME SUMOYLATION OF INTRACELLULAR RECEPTORS 29 3.56e-01 9.90e-02 8.55e-01
REACTOME TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS 43 3.57e-01 -8.12e-02 8.55e-01
REACTOME GLUCAGON TYPE LIGAND RECEPTORS 32 3.57e-01 9.41e-02 8.55e-01
REACTOME LONG TERM POTENTIATION 22 3.58e-01 1.13e-01 8.55e-01
REACTOME CITRIC ACID CYCLE TCA CYCLE 21 3.58e-01 -1.16e-01 8.55e-01
REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE 20 3.58e-01 -1.19e-01 8.55e-01
REACTOME SIGNALING BY FGFR2 IN DISEASE 42 3.58e-01 8.19e-02 8.55e-01
REACTOME MITOPHAGY 28 3.58e-01 -1.00e-01 8.55e-01
REACTOME LRR FLII INTERACTING PROTEIN 1 LRRFIP1 ACTIVATES TYPE I IFN PRODUCTION 5 3.58e-01 -2.37e-01 8.55e-01
REACTOME CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS 100 3.59e-01 5.30e-02 8.55e-01
REACTOME ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING 9 3.60e-01 -1.76e-01 8.55e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS 5 3.60e-01 2.36e-01 8.55e-01
REACTOME PROLACTIN RECEPTOR SIGNALING 15 3.61e-01 -1.36e-01 8.55e-01
REACTOME SHC RELATED EVENTS TRIGGERED BY IGF1R 9 3.61e-01 1.76e-01 8.55e-01
REACTOME CREB3 FACTORS ACTIVATE GENES 8 3.62e-01 1.86e-01 8.55e-01
REACTOME BINDING OF TCF LEF CTNNB1 TO TARGET GENE PROMOTERS 8 3.62e-01 -1.86e-01 8.55e-01
REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING 12 3.66e-01 -1.51e-01 8.62e-01
REACTOME FATTY ACID METABOLISM 170 3.67e-01 4.01e-02 8.64e-01
REACTOME SIGNALING BY ERBB4 57 3.68e-01 6.89e-02 8.66e-01
REACTOME ERKS ARE INACTIVATED 13 3.69e-01 1.44e-01 8.66e-01
REACTOME OVARIAN TUMOR DOMAIN PROTEASES 36 3.69e-01 -8.65e-02 8.66e-01
REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS 6 3.71e-01 2.11e-01 8.66e-01
REACTOME ACTIVATION OF BH3 ONLY PROTEINS 30 3.73e-01 -9.40e-02 8.66e-01
REACTOME SIGNALING BY CSF1 M CSF IN MYELOID CELLS 30 3.73e-01 9.40e-02 8.66e-01
REACTOME SARS COV 2 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS 12 3.75e-01 -1.48e-01 8.66e-01
REACTOME PYROPTOSIS 27 3.75e-01 9.86e-02 8.66e-01
REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A 26 3.76e-01 -1.00e-01 8.66e-01
REACTOME NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY 6 3.76e-01 -2.09e-01 8.66e-01
REACTOME TLR3 MEDIATED TICAM1 DEPENDENT PROGRAMMED CELL DEATH 6 3.77e-01 -2.08e-01 8.66e-01
REACTOME SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA 52 3.78e-01 7.07e-02 8.66e-01
REACTOME FGFR1C LIGAND BINDING AND ACTIVATION 11 3.78e-01 1.54e-01 8.66e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX3 94 3.78e-01 -5.26e-02 8.66e-01
REACTOME NFE2L2 REGULATING ANTI OXIDANT DETOXIFICATION ENZYMES 17 3.78e-01 -1.23e-01 8.66e-01
REACTOME COHESIN LOADING ONTO CHROMATIN 8 3.79e-01 -1.80e-01 8.66e-01
REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT 236 3.79e-01 3.33e-02 8.66e-01
REACTOME SARS COV 2 TARGETS PDZ PROTEINS IN CELL CELL JUNCTION 5 3.79e-01 2.27e-01 8.66e-01
REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS 83 3.79e-01 -5.58e-02 8.66e-01
REACTOME PI3K EVENTS IN ERBB2 SIGNALING 16 3.80e-01 1.27e-01 8.66e-01
REACTOME VLDLR INTERNALISATION AND DEGRADATION 16 3.80e-01 1.27e-01 8.66e-01
REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK 28 3.80e-01 -9.58e-02 8.66e-01
REACTOME FGFR2 LIGAND BINDING AND ACTIVATION 19 3.80e-01 1.16e-01 8.66e-01
REACTOME STAT5 ACTIVATION 7 3.82e-01 1.91e-01 8.66e-01
REACTOME REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM 11 3.82e-01 1.52e-01 8.66e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS 8 3.82e-01 -1.78e-01 8.66e-01
REACTOME BH3 ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI APOPTOTIC BCL 2 MEMBERS 9 3.82e-01 -1.68e-01 8.66e-01
REACTOME SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL 25 3.82e-01 -1.01e-01 8.66e-01
REACTOME BIOTIN TRANSPORT AND METABOLISM 10 3.84e-01 -1.59e-01 8.68e-01
REACTOME PROTEIN REPAIR 6 3.85e-01 2.05e-01 8.68e-01
REACTOME MISCELLANEOUS TRANSPORT AND BINDING EVENTS 24 3.85e-01 -1.02e-01 8.68e-01
REACTOME EPITHELIAL MESENCHYMAL TRANSITION EMT DURING GASTRULATION 7 3.86e-01 1.89e-01 8.68e-01
REACTOME PROTEIN UBIQUITINATION 76 3.86e-01 -5.75e-02 8.68e-01
REACTOME SODIUM PROTON EXCHANGERS 7 3.87e-01 -1.89e-01 8.68e-01
REACTOME FGFR3 LIGAND BINDING AND ACTIVATION 12 3.87e-01 1.44e-01 8.68e-01
REACTOME SIGNALING BY FGFR 85 3.89e-01 5.40e-02 8.70e-01
REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX 36 3.90e-01 -8.27e-02 8.70e-01
REACTOME CD209 DC SIGN SIGNALING 20 3.91e-01 -1.11e-01 8.70e-01
REACTOME PLASMA LIPOPROTEIN CLEARANCE 37 3.93e-01 8.12e-02 8.70e-01
REACTOME ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS 11 3.93e-01 1.49e-01 8.70e-01
REACTOME MET ACTIVATES RAP1 AND RAC1 11 3.93e-01 1.49e-01 8.70e-01
REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 22 3.93e-01 1.05e-01 8.70e-01
REACTOME REGULATION OF IFNA IFNB SIGNALING 23 3.93e-01 1.03e-01 8.70e-01
REACTOME KILLING MECHANISMS 11 3.94e-01 -1.49e-01 8.70e-01
REACTOME PENTOSE PHOSPHATE PATHWAY 12 3.94e-01 -1.42e-01 8.70e-01
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION 250 3.94e-01 3.13e-02 8.70e-01
REACTOME INTERLEUKIN 2 SIGNALING 11 3.95e-01 -1.48e-01 8.70e-01
REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION 23 3.96e-01 1.02e-01 8.70e-01
REACTOME FGFRL1 MODULATION OF FGFR1 SIGNALING 13 3.96e-01 1.36e-01 8.70e-01
REACTOME RUNX3 REGULATES WNT SIGNALING 8 3.96e-01 -1.73e-01 8.70e-01
REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS 21 3.97e-01 -1.07e-01 8.70e-01
REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS 42 3.97e-01 7.55e-02 8.70e-01
REACTOME SIGNALING BY MST1 5 3.98e-01 2.18e-01 8.70e-01
REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN 76 3.98e-01 -5.60e-02 8.70e-01
REACTOME SIGNALING BY EGFR IN CANCER 25 3.99e-01 9.75e-02 8.70e-01
REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION 36 3.99e-01 -8.11e-02 8.71e-01
REACTOME ANTIGEN PROCESSING CROSS PRESENTATION 98 4.01e-01 4.91e-02 8.72e-01
REACTOME RHO GTPASES ACTIVATE NADPH OXIDASES 21 4.01e-01 1.06e-01 8.72e-01
REACTOME SYNTHESIS OF PIPS AT THE ER MEMBRANE 5 4.01e-01 -2.17e-01 8.72e-01
REACTOME REGULATION OF MECP2 EXPRESSION AND ACTIVITY 30 4.02e-01 -8.84e-02 8.72e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE 5 4.02e-01 2.16e-01 8.72e-01
REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 122 4.04e-01 4.38e-02 8.72e-01
REACTOME MAPK6 MAPK4 SIGNALING 91 4.05e-01 -5.05e-02 8.72e-01
REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI 26 4.05e-01 9.43e-02 8.72e-01
REACTOME FLT3 SIGNALING 38 4.05e-01 -7.80e-02 8.72e-01
REACTOME TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS 29 4.06e-01 8.91e-02 8.72e-01
REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS 16 4.07e-01 1.20e-01 8.72e-01
REACTOME CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA 63 4.09e-01 -6.02e-02 8.72e-01
REACTOME GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION 42 4.09e-01 7.37e-02 8.72e-01
REACTOME RND3 GTPASE CYCLE 41 4.09e-01 -7.45e-02 8.72e-01
REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES 21 4.09e-01 1.04e-01 8.72e-01
REACTOME CYCLIN D ASSOCIATED EVENTS IN G1 46 4.10e-01 7.03e-02 8.72e-01
REACTOME FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS 8 4.10e-01 -1.68e-01 8.72e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES 43 4.10e-01 7.26e-02 8.72e-01
REACTOME RELEASE OF HH NP FROM THE SECRETING CELL 8 4.12e-01 1.68e-01 8.72e-01
REACTOME FOXO MEDIATED TRANSCRIPTION 65 4.12e-01 5.89e-02 8.72e-01
REACTOME INTESTINAL ABSORPTION 5 4.12e-01 -2.12e-01 8.72e-01
REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS 111 4.12e-01 -4.50e-02 8.72e-01
REACTOME PREDNISONE ADME 10 4.13e-01 1.50e-01 8.72e-01
REACTOME ATTACHMENT OF GPI ANCHOR TO UPAR 7 4.13e-01 -1.79e-01 8.72e-01
REACTOME GROWTH HORMONE RECEPTOR SIGNALING 24 4.13e-01 -9.65e-02 8.72e-01
REACTOME SIGNALING BY ALK 26 4.14e-01 9.25e-02 8.72e-01
REACTOME RHOC GTPASE CYCLE 71 4.14e-01 -5.60e-02 8.72e-01
REACTOME CD163 MEDIATING AN ANTI INFLAMMATORY RESPONSE 9 4.16e-01 -1.57e-01 8.73e-01
REACTOME COMPLEMENT CASCADE 54 4.16e-01 6.40e-02 8.73e-01
REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL 58 4.16e-01 -6.17e-02 8.73e-01
REACTOME TBC RABGAPS 40 4.17e-01 -7.42e-02 8.73e-01
REACTOME DIGESTION OF DIETARY CARBOHYDRATE 6 4.18e-01 -1.91e-01 8.73e-01
REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION 11 4.19e-01 -1.41e-01 8.74e-01
REACTOME INOSITOL PHOSPHATE METABOLISM 45 4.19e-01 -6.96e-02 8.74e-01
REACTOME ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA 15 4.20e-01 -1.20e-01 8.74e-01
REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE 37 4.23e-01 7.62e-02 8.74e-01
REACTOME SIGNALING BY NOTCH1 T 7 9 NOTCH1 M1580 K2555 TRANSLOCATION MUTANT 7 4.23e-01 1.75e-01 8.74e-01
REACTOME HSF1 ACTIVATION 29 4.24e-01 -8.58e-02 8.74e-01
REACTOME HDR THROUGH SINGLE STRAND ANNEALING SSA 37 4.24e-01 -7.59e-02 8.74e-01
REACTOME MITOTIC METAPHASE AND ANAPHASE 228 4.24e-01 -3.07e-02 8.74e-01
REACTOME DEFECTIVE EXT2 CAUSES EXOSTOSES 2 12 4.24e-01 1.33e-01 8.74e-01
REACTOME BETA OXIDATION OF BUTANOYL COA TO ACETYL COA 5 4.25e-01 2.06e-01 8.74e-01
REACTOME INTERACTION BETWEEN L1 AND ANKYRINS 30 4.26e-01 8.41e-02 8.74e-01
REACTOME REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO 10 4.26e-01 1.45e-01 8.74e-01
REACTOME TERMINATION OF TRANSLESION DNA SYNTHESIS 32 4.27e-01 -8.12e-02 8.74e-01
REACTOME DEFECTIVE CHST3 CAUSES SEDCJD 7 4.27e-01 1.73e-01 8.74e-01
REACTOME REGULATION OF PTEN GENE TRANSCRIPTION 59 4.27e-01 -5.98e-02 8.74e-01
REACTOME RIBAVIRIN ADME 11 4.28e-01 1.38e-01 8.74e-01
REACTOME METABOLISM OF POLYAMINES 56 4.28e-01 -6.13e-02 8.74e-01
REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS 29 4.29e-01 8.49e-02 8.74e-01
REACTOME FREE FATTY ACIDS REGULATE INSULIN SECRETION 10 4.29e-01 -1.45e-01 8.74e-01
REACTOME RAC1 GTPASE CYCLE 172 4.29e-01 3.50e-02 8.74e-01
REACTOME MITOCHONDRIAL UNCOUPLING 5 4.31e-01 -2.04e-01 8.75e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION 36 4.32e-01 7.57e-02 8.75e-01
REACTOME INTERLEUKIN 27 SIGNALING 11 4.32e-01 -1.37e-01 8.75e-01
REACTOME E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS 58 4.32e-01 -5.96e-02 8.75e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS 14 4.32e-01 -1.21e-01 8.75e-01
REACTOME DRUG ADME 103 4.33e-01 -4.48e-02 8.75e-01
REACTOME NEGATIVE REGULATION OF ACTIVITY OF TFAP2 AP 2 FAMILY TRANSCRIPTION FACTORS 10 4.33e-01 1.43e-01 8.75e-01
REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION 32 4.33e-01 8.00e-02 8.75e-01
REACTOME INACTIVATION OF CDC42 AND RAC1 8 4.34e-01 1.60e-01 8.75e-01
REACTOME SIGNALING BY INTERLEUKINS 444 4.37e-01 2.15e-02 8.80e-01
REACTOME SEMA4D IN SEMAPHORIN SIGNALING 24 4.37e-01 9.16e-02 8.80e-01
REACTOME SMAC XIAP REGULATED APOPTOTIC RESPONSE 7 4.39e-01 -1.69e-01 8.80e-01
REACTOME HORMONE LIGAND BINDING RECEPTORS 12 4.40e-01 1.29e-01 8.80e-01
REACTOME ROBO RECEPTORS BIND AKAP5 9 4.40e-01 1.49e-01 8.80e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION 45 4.40e-01 -6.65e-02 8.80e-01
REACTOME RUNX3 REGULATES NOTCH SIGNALING 13 4.40e-01 -1.24e-01 8.80e-01
REACTOME SIGNALING BY RETINOIC ACID 41 4.41e-01 6.96e-02 8.80e-01
REACTOME DIGESTION 17 4.41e-01 -1.08e-01 8.80e-01
REACTOME CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY 12 4.41e-01 -1.28e-01 8.80e-01
REACTOME SLC TRANSPORTER DISORDERS 94 4.43e-01 4.58e-02 8.81e-01
REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE 20 4.43e-01 9.90e-02 8.81e-01
REACTOME TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA 17 4.44e-01 1.07e-01 8.81e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE 5 4.45e-01 1.97e-01 8.81e-01
REACTOME ATORVASTATIN ADME 9 4.45e-01 -1.47e-01 8.81e-01
REACTOME ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS 20 4.45e-01 -9.86e-02 8.81e-01
REACTOME CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS 19 4.46e-01 1.01e-01 8.82e-01
REACTOME FRUCTOSE METABOLISM 7 4.48e-01 1.66e-01 8.83e-01
REACTOME SENSING OF DNA DOUBLE STRAND BREAKS 6 4.49e-01 -1.79e-01 8.83e-01
REACTOME REGULATION OF LIPID METABOLISM BY PPARALPHA 115 4.49e-01 -4.09e-02 8.83e-01
REACTOME STRIATED MUSCLE CONTRACTION 35 4.49e-01 -7.39e-02 8.84e-01
REACTOME DISEASES OF MITOTIC CELL CYCLE 37 4.50e-01 -7.17e-02 8.84e-01
REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS 17 4.51e-01 -1.06e-01 8.84e-01
REACTOME DOPAMINE RECEPTORS 5 4.51e-01 1.95e-01 8.84e-01
REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES 14 4.53e-01 1.16e-01 8.84e-01
REACTOME TRANSLESION SYNTHESIS BY POLH 19 4.53e-01 -9.94e-02 8.84e-01
REACTOME POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION 27 4.54e-01 -8.33e-02 8.84e-01
REACTOME DNA REPLICATION INITIATION 7 4.54e-01 -1.64e-01 8.84e-01
REACTOME SYNTHESIS OF PI 5 4.54e-01 -1.93e-01 8.84e-01
REACTOME SARS COV INFECTIONS 392 4.55e-01 -2.20e-02 8.84e-01
REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION 15 4.56e-01 1.11e-01 8.84e-01
REACTOME EGFR INTERACTS WITH PHOSPHOLIPASE C GAMMA 9 4.56e-01 1.44e-01 8.84e-01
REACTOME INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES 28 4.57e-01 8.11e-02 8.84e-01
REACTOME LDL CLEARANCE 19 4.58e-01 9.85e-02 8.84e-01
REACTOME DSCAM INTERACTIONS 11 4.58e-01 1.29e-01 8.84e-01
REACTOME HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS 9 4.58e-01 1.43e-01 8.84e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING 5 4.58e-01 -1.91e-01 8.84e-01
REACTOME NETRIN MEDIATED REPULSION SIGNALS 8 4.59e-01 1.51e-01 8.84e-01
REACTOME HDR THROUGH HOMOLOGOUS RECOMBINATION HRR 66 4.60e-01 -5.26e-02 8.85e-01
REACTOME LEISHMANIA INFECTION 156 4.62e-01 3.41e-02 8.88e-01
REACTOME METALLOTHIONEINS BIND METALS 11 4.63e-01 1.28e-01 8.89e-01
REACTOME PROCESSING OF SMDT1 16 4.64e-01 -1.06e-01 8.89e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD4 15 4.65e-01 1.09e-01 8.89e-01
REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE 15 4.65e-01 -1.09e-01 8.89e-01
REACTOME RND1 GTPASE CYCLE 41 4.65e-01 6.59e-02 8.90e-01
REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS 12 4.67e-01 1.21e-01 8.91e-01
REACTOME REGULATION OF INSULIN SECRETION 77 4.67e-01 4.79e-02 8.91e-01
REACTOME SIGNALING BY NODAL 20 4.69e-01 9.34e-02 8.94e-01
REACTOME HYALURONAN METABOLISM 17 4.70e-01 1.01e-01 8.94e-01
REACTOME MET INTERACTS WITH TNS PROTEINS 5 4.71e-01 1.86e-01 8.94e-01
REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT 99 4.72e-01 -4.19e-02 8.95e-01
REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES 12 4.72e-01 1.20e-01 8.95e-01
REACTOME HDR THROUGH MMEJ ALT NHEJ 12 4.73e-01 -1.20e-01 8.96e-01
REACTOME PROTEIN FOLDING 96 4.74e-01 4.22e-02 8.96e-01
REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS 35 4.74e-01 -6.99e-02 8.96e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE 20 4.75e-01 -9.23e-02 8.96e-01
REACTOME NGF STIMULATED TRANSCRIPTION 38 4.76e-01 6.68e-02 8.97e-01
REACTOME NS1 MEDIATED EFFECTS ON HOST PATHWAYS 41 4.76e-01 -6.43e-02 8.97e-01
REACTOME ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS 7 4.78e-01 -1.55e-01 8.97e-01
REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON 17 4.78e-01 9.95e-02 8.97e-01
REACTOME DEFECTIVE B4GALT1 CAUSES B4GALT1 CDG CDG 2D 8 4.79e-01 -1.44e-01 8.97e-01
REACTOME DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15 8 4.81e-01 -1.44e-01 8.97e-01
REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION 16 4.81e-01 1.02e-01 8.97e-01
REACTOME NICOTINAMIDE SALVAGING 19 4.81e-01 9.33e-02 8.97e-01
REACTOME REGULATION OF NPAS4 GENE TRANSCRIPTION 5 4.81e-01 -1.82e-01 8.97e-01
REACTOME LYSINE CATABOLISM 12 4.83e-01 1.17e-01 8.97e-01
REACTOME TYSND1 CLEAVES PEROXISOMAL PROTEINS 7 4.83e-01 -1.53e-01 8.97e-01
REACTOME SMOOTH MUSCLE CONTRACTION 43 4.84e-01 6.16e-02 8.97e-01
REACTOME IRF3 MEDIATED INDUCTION OF TYPE I IFN 13 4.85e-01 -1.12e-01 8.97e-01
REACTOME NOD1 2 SIGNALING PATHWAY 33 4.85e-01 7.02e-02 8.97e-01
REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING 16 4.85e-01 1.01e-01 8.97e-01
REACTOME PRE NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM 6 4.85e-01 -1.65e-01 8.97e-01
REACTOME ANDROGEN BIOSYNTHESIS 11 4.86e-01 -1.21e-01 8.97e-01
REACTOME ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS 20 4.87e-01 -8.99e-02 8.97e-01
REACTOME ARYL HYDROCARBON RECEPTOR SIGNALLING 6 4.88e-01 1.64e-01 8.97e-01
REACTOME REGULATION OF NPAS4 GENE EXPRESSION 13 4.88e-01 -1.11e-01 8.97e-01
REACTOME RHOF GTPASE CYCLE 40 4.88e-01 6.33e-02 8.97e-01
REACTOME SYNTHESIS OF PA 38 4.89e-01 -6.48e-02 8.97e-01
REACTOME COENZYME A BIOSYNTHESIS 8 4.89e-01 1.41e-01 8.97e-01
REACTOME NUCLEOTIDE BIOSYNTHESIS 14 4.90e-01 -1.07e-01 8.97e-01
REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION 32 4.90e-01 7.05e-02 8.97e-01
REACTOME ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY 10 4.90e-01 -1.26e-01 8.97e-01
REACTOME ERYTHROPOIETIN ACTIVATES STAT5 7 4.91e-01 -1.50e-01 8.97e-01
REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES 34 4.91e-01 6.82e-02 8.97e-01
REACTOME KEAP1 NFE2L2 PATHWAY 104 4.91e-01 -3.90e-02 8.97e-01
REACTOME SIGNAL AMPLIFICATION 33 4.92e-01 6.91e-02 8.97e-01
REACTOME FLT3 SIGNALING THROUGH SRC FAMILY KINASES 6 4.92e-01 -1.62e-01 8.97e-01
REACTOME RRNA PROCESSING 192 4.95e-01 -2.86e-02 8.99e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS 14 4.95e-01 1.05e-01 8.99e-01
REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE 17 4.96e-01 -9.54e-02 8.99e-01
REACTOME METABOLISM OF AMINE DERIVED HORMONES 17 4.96e-01 9.54e-02 8.99e-01
REACTOME PERK REGULATES GENE EXPRESSION 31 4.96e-01 7.06e-02 8.99e-01
REACTOME CONSTITUTIVE SIGNALING BY EGFRVIII 15 4.97e-01 1.01e-01 8.99e-01
REACTOME SIGNALING BY ERBB2 50 4.97e-01 5.55e-02 8.99e-01
REACTOME ERYTHROPOIETIN ACTIVATES RAS 14 5.00e-01 1.04e-01 9.00e-01
REACTOME CD28 CO STIMULATION 32 5.00e-01 -6.89e-02 9.00e-01
REACTOME EPHA MEDIATED GROWTH CONE COLLAPSE 29 5.02e-01 7.21e-02 9.00e-01
REACTOME PHASE II CONJUGATION OF COMPOUNDS 102 5.02e-01 -3.85e-02 9.00e-01
REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS 12 5.03e-01 1.12e-01 9.00e-01
REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA 11 5.03e-01 -1.17e-01 9.00e-01
REACTOME DEFECTS IN BIOTIN BTN METABOLISM 8 5.04e-01 -1.37e-01 9.00e-01
REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS 55 5.05e-01 -5.20e-02 9.00e-01
REACTOME RHOBTB GTPASE CYCLE 34 5.05e-01 -6.60e-02 9.00e-01
REACTOME DEGRADATION OF AXIN 54 5.05e-01 -5.24e-02 9.00e-01
REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS 16 5.06e-01 9.61e-02 9.00e-01
REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION 35 5.06e-01 6.49e-02 9.00e-01
REACTOME ACYL CHAIN REMODELLING OF PS 22 5.07e-01 -8.18e-02 9.00e-01
REACTOME SEPARATION OF SISTER CHROMATIDS 184 5.07e-01 -2.83e-02 9.00e-01
REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING 13 5.09e-01 -1.06e-01 9.00e-01
REACTOME XENOBIOTICS 22 5.10e-01 8.12e-02 9.00e-01
REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 19 5.10e-01 8.73e-02 9.00e-01
REACTOME SARS COV 1 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS 16 5.10e-01 -9.51e-02 9.00e-01
REACTOME TRYPTOPHAN CATABOLISM 14 5.11e-01 1.01e-01 9.00e-01
REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE 109 5.12e-01 3.64e-02 9.00e-01
REACTOME SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION 8 5.13e-01 1.34e-01 9.00e-01
REACTOME HEME BIOSYNTHESIS 13 5.13e-01 -1.05e-01 9.00e-01
REACTOME TYROSINE CATABOLISM 5 5.14e-01 1.69e-01 9.00e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA 25 5.14e-01 -7.53e-02 9.00e-01
REACTOME STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES 16 5.15e-01 -9.41e-02 9.00e-01
REACTOME PROGRAMMED CELL DEATH 204 5.15e-01 2.65e-02 9.00e-01
REACTOME BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA 5 5.15e-01 1.68e-01 9.00e-01
REACTOME O LINKED GLYCOSYLATION OF MUCINS 61 5.16e-01 4.81e-02 9.00e-01
REACTOME TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA 36 5.16e-01 -6.26e-02 9.00e-01
REACTOME KERATAN SULFATE KERATIN METABOLISM 34 5.16e-01 6.43e-02 9.00e-01
REACTOME DISINHIBITION OF SNARE FORMATION 5 5.17e-01 1.67e-01 9.00e-01
REACTOME ABACAVIR TRANSMEMBRANE TRANSPORT 5 5.17e-01 -1.67e-01 9.00e-01
REACTOME PHOSPHORYLATION OF THE APC C 20 5.17e-01 -8.37e-02 9.00e-01
REACTOME INITIATION OF NUCLEAR ENVELOPE NE REFORMATION 18 5.17e-01 8.82e-02 9.00e-01
REACTOME VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS 42 5.17e-01 5.78e-02 9.00e-01
REACTOME SIGNALING BY FGFR4 IN DISEASE 11 5.18e-01 1.13e-01 9.00e-01
REACTOME SIGNALING BY FGFR2 72 5.18e-01 4.40e-02 9.00e-01
REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN 19 5.18e-01 8.56e-02 9.00e-01
REACTOME SIGNALING BY PTK6 54 5.20e-01 5.07e-02 9.00e-01
REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY 23 5.21e-01 7.74e-02 9.00e-01
REACTOME TRP CHANNELS 27 5.21e-01 -7.14e-02 9.00e-01
REACTOME TOXICITY OF BOTULINUM TOXIN TYPE D BOTD 5 5.21e-01 1.66e-01 9.00e-01
REACTOME VITAMIN C ASCORBATE METABOLISM 8 5.22e-01 1.31e-01 9.01e-01
REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY 72 5.23e-01 4.36e-02 9.01e-01
REACTOME LTC4 CYSLTR MEDIATED IL4 PRODUCTION 6 5.23e-01 1.51e-01 9.01e-01
REACTOME SENSORY PROCESSING OF SOUND 72 5.25e-01 4.34e-02 9.01e-01
REACTOME OAS ANTIVIRAL RESPONSE 8 5.25e-01 -1.30e-01 9.01e-01
REACTOME CHOLINE CATABOLISM 6 5.25e-01 -1.50e-01 9.01e-01
REACTOME RIPK1 MEDIATED REGULATED NECROSIS 30 5.26e-01 6.69e-02 9.01e-01
REACTOME TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX 14 5.26e-01 -9.79e-02 9.01e-01
REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS 11 5.29e-01 1.10e-01 9.04e-01
REACTOME G PROTEIN ACTIVATION 24 5.30e-01 7.41e-02 9.04e-01
REACTOME REPRESSION OF WNT TARGET GENES 14 5.30e-01 -9.69e-02 9.04e-01
REACTOME NR1H2 AND NR1H3 MEDIATED SIGNALING 46 5.30e-01 -5.35e-02 9.04e-01
REACTOME ACTIVATION OF AMPK DOWNSTREAM OF NMDARS 28 5.30e-01 6.85e-02 9.04e-01
REACTOME DARPP 32 EVENTS 24 5.33e-01 7.35e-02 9.04e-01
REACTOME UNFOLDED PROTEIN RESPONSE UPR 88 5.33e-01 3.84e-02 9.04e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES 49 5.34e-01 -5.13e-02 9.04e-01
REACTOME SCAVENGING BY CLASS F RECEPTORS 6 5.35e-01 1.46e-01 9.04e-01
REACTOME DISEASES OF CARBOHYDRATE METABOLISM 31 5.35e-01 -6.43e-02 9.04e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS 7 5.36e-01 1.35e-01 9.04e-01
REACTOME SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS 43 5.36e-01 -5.45e-02 9.04e-01
REACTOME RHO GTPASES ACTIVATE CIT 19 5.36e-01 -8.20e-02 9.04e-01
REACTOME SEROTONIN NEUROTRANSMITTER RELEASE CYCLE 17 5.36e-01 -8.66e-02 9.04e-01
REACTOME HIV TRANSCRIPTION INITIATION 43 5.36e-01 -5.45e-02 9.04e-01
REACTOME TNFR2 NON CANONICAL NF KB PATHWAY 96 5.37e-01 -3.65e-02 9.04e-01
REACTOME RHOD GTPASE CYCLE 49 5.37e-01 5.10e-02 9.04e-01
REACTOME FGFR2 ALTERNATIVE SPLICING 27 5.38e-01 -6.85e-02 9.04e-01
REACTOME INFLUENZA INFECTION 149 5.38e-01 2.92e-02 9.04e-01
REACTOME MET ACTIVATES PTK2 SIGNALING 30 5.39e-01 -6.47e-02 9.05e-01
REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION 13 5.40e-01 -9.82e-02 9.05e-01
REACTOME FC EPSILON RECEPTOR FCERI SIGNALING 127 5.41e-01 -3.14e-02 9.06e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS 11 5.42e-01 1.06e-01 9.07e-01
REACTOME CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION 11 5.43e-01 -1.06e-01 9.07e-01
REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE 21 5.43e-01 -7.67e-02 9.07e-01
REACTOME TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS 26 5.44e-01 -6.88e-02 9.07e-01
REACTOME ATTENUATION PHASE 27 5.44e-01 -6.75e-02 9.07e-01
REACTOME RIP MEDIATED NFKB ACTIVATION VIA ZBP1 16 5.45e-01 -8.74e-02 9.08e-01
REACTOME SIGNALING BY ERBB2 ECD MUTANTS 16 5.47e-01 8.70e-02 9.09e-01
REACTOME LIGAND RECEPTOR INTERACTIONS 8 5.48e-01 1.23e-01 9.11e-01
REACTOME MEMBRANE TRAFFICKING 603 5.50e-01 -1.43e-02 9.13e-01
REACTOME INTERLEUKIN 12 SIGNALING 43 5.51e-01 5.25e-02 9.14e-01
REACTOME REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS 15 5.52e-01 8.88e-02 9.14e-01
REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS 38 5.54e-01 -5.55e-02 9.17e-01
REACTOME GABA RECEPTOR ACTIVATION 57 5.55e-01 4.52e-02 9.17e-01
REACTOME PROPIONYL COA CATABOLISM 5 5.56e-01 -1.52e-01 9.17e-01
REACTOME GERM LAYER FORMATION AT GASTRULATION 17 5.56e-01 8.25e-02 9.17e-01
REACTOME PTK6 REGULATES CELL CYCLE 6 5.57e-01 -1.38e-01 9.18e-01
REACTOME RHO GTPASES ACTIVATE WASPS AND WAVES 34 5.58e-01 -5.81e-02 9.18e-01
REACTOME ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS 27 5.58e-01 6.52e-02 9.18e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS 5 5.59e-01 1.51e-01 9.18e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2 13 5.60e-01 9.34e-02 9.18e-01
REACTOME OTHER INTERLEUKIN SIGNALING 24 5.60e-01 6.88e-02 9.18e-01
REACTOME REDUCTION OF CYTOSOLIC CA LEVELS 11 5.61e-01 -1.01e-01 9.19e-01
REACTOME AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY 8 5.62e-01 1.19e-01 9.19e-01
REACTOME DEGRADATION OF CYSTEINE AND HOMOCYSTEINE 15 5.62e-01 8.65e-02 9.19e-01
REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS 46 5.63e-01 -4.93e-02 9.19e-01
REACTOME INTERLEUKIN 23 SIGNALING 9 5.63e-01 -1.11e-01 9.19e-01
REACTOME BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA 5 5.65e-01 1.48e-01 9.21e-01
REACTOME DNA DAMAGE REVERSAL 8 5.66e-01 -1.17e-01 9.21e-01
REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS 15 5.66e-01 8.56e-02 9.21e-01
REACTOME RESPONSE TO METAL IONS 14 5.69e-01 8.79e-02 9.24e-01
REACTOME SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL 8 5.69e-01 -1.16e-01 9.24e-01
REACTOME ERBB2 ACTIVATES PTK6 SIGNALING 13 5.70e-01 9.11e-02 9.24e-01
REACTOME CHL1 INTERACTIONS 9 5.71e-01 1.09e-01 9.25e-01
REACTOME GLYCOGEN METABOLISM 22 5.72e-01 -6.95e-02 9.27e-01
REACTOME REGULATION OF RUNX3 EXPRESSION AND ACTIVITY 54 5.73e-01 -4.44e-02 9.27e-01
REACTOME EPHB MEDIATED FORWARD SIGNALING 41 5.74e-01 5.08e-02 9.27e-01
REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS 9 5.75e-01 1.08e-01 9.27e-01
REACTOME SIGNALING BY ERYTHROPOIETIN 25 5.75e-01 6.48e-02 9.27e-01
REACTOME RHO GTPASES ACTIVATE PAKS 19 5.76e-01 -7.42e-02 9.27e-01
REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS 63 5.76e-01 -4.08e-02 9.27e-01
REACTOME RHOG GTPASE CYCLE 71 5.77e-01 3.83e-02 9.27e-01
REACTOME GRB2 EVENTS IN ERBB2 SIGNALING 16 5.80e-01 7.99e-02 9.31e-01
REACTOME SYNTHESIS OF 15 EICOSATETRAENOIC ACID DERIVATIVES 6 5.81e-01 1.30e-01 9.31e-01
REACTOME CYTOPROTECTION BY HMOX1 59 5.81e-01 4.16e-02 9.31e-01
REACTOME HS GAG BIOSYNTHESIS 28 5.81e-01 6.03e-02 9.31e-01
REACTOME SODIUM CALCIUM EXCHANGERS 11 5.83e-01 -9.56e-02 9.31e-01
REACTOME PROLONGED ERK ACTIVATION EVENTS 14 5.84e-01 8.46e-02 9.31e-01
REACTOME SIGNALING BY SCF KIT 42 5.84e-01 4.89e-02 9.31e-01
REACTOME P75NTR SIGNALS VIA NF KB 15 5.84e-01 8.17e-02 9.31e-01
REACTOME TRANSPORT OF RCBL WITHIN THE BODY 8 5.86e-01 -1.11e-01 9.33e-01
REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES 46 5.87e-01 -4.63e-02 9.33e-01
REACTOME INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL 14 5.87e-01 8.38e-02 9.33e-01
REACTOME GLYCEROPHOSPHOLIPID CATABOLISM 7 5.87e-01 1.19e-01 9.33e-01
REACTOME MET RECEPTOR ACTIVATION 6 5.87e-01 1.28e-01 9.33e-01
REACTOME P75NTR REGULATES AXONOGENESIS 9 5.88e-01 1.04e-01 9.33e-01
REACTOME VITAMIN B2 RIBOFLAVIN METABOLISM 7 5.91e-01 -1.17e-01 9.34e-01
REACTOME PROCESSING OF INTRONLESS PRE MRNAS 19 5.91e-01 -7.11e-02 9.34e-01
REACTOME NGF INDEPENDANT TRKA ACTIVATION 5 5.92e-01 1.39e-01 9.34e-01
REACTOME SIGNALING BY LRP5 MUTANTS 6 5.92e-01 1.26e-01 9.34e-01
REACTOME EPH EPHRIN MEDIATED REPULSION OF CELLS 50 5.93e-01 4.37e-02 9.34e-01
REACTOME RHOU GTPASE CYCLE 37 5.94e-01 5.07e-02 9.34e-01
REACTOME SPRY REGULATION OF FGF SIGNALING 16 5.94e-01 7.70e-02 9.34e-01
REACTOME PARACETAMOL ADME 26 5.94e-01 -6.03e-02 9.34e-01
REACTOME DAP12 SIGNALING 27 5.94e-01 -5.92e-02 9.34e-01
REACTOME ABC TRANSPORTER DISORDERS 76 5.95e-01 -3.53e-02 9.34e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1 20 5.97e-01 6.83e-02 9.34e-01
REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION 10 5.98e-01 9.63e-02 9.34e-01
REACTOME AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA 54 5.98e-01 -4.15e-02 9.34e-01
REACTOME SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS 14 5.99e-01 -8.11e-02 9.34e-01
REACTOME METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS 122 5.99e-01 -2.75e-02 9.34e-01
REACTOME SERINE BIOSYNTHESIS 9 5.99e-01 -1.01e-01 9.34e-01
REACTOME SHC1 EVENTS IN ERBB4 SIGNALING 14 6.00e-01 8.09e-02 9.34e-01
REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX 31 6.00e-01 -5.44e-02 9.34e-01
REACTOME EFFECTS OF PIP2 HYDROLYSIS 26 6.01e-01 -5.92e-02 9.34e-01
REACTOME SIGNALING BY MRAS COMPLEX MUTANTS 7 6.03e-01 1.14e-01 9.34e-01
REACTOME NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 11 6.03e-01 9.06e-02 9.34e-01
REACTOME POLB DEPENDENT LONG PATCH BASE EXCISION REPAIR 8 6.03e-01 -1.06e-01 9.34e-01
REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE 71 6.03e-01 -3.57e-02 9.34e-01
REACTOME PLASMA LIPOPROTEIN REMODELING 33 6.04e-01 -5.22e-02 9.34e-01
REACTOME GPVI MEDIATED ACTIVATION CASCADE 35 6.04e-01 5.06e-02 9.34e-01
REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV 1 INFECTION 5 6.05e-01 1.34e-01 9.34e-01
REACTOME APOPTOTIC FACTOR MEDIATED RESPONSE 19 6.05e-01 -6.86e-02 9.34e-01
REACTOME ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY 10 6.05e-01 -9.45e-02 9.34e-01
REACTOME GLYCOSPHINGOLIPID METABOLISM 39 6.06e-01 -4.78e-02 9.34e-01
REACTOME DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS 25 6.07e-01 -5.95e-02 9.34e-01
REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE 63 6.08e-01 3.73e-02 9.34e-01
REACTOME G0 AND EARLY G1 27 6.09e-01 -5.69e-02 9.34e-01
REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY 15 6.10e-01 -7.61e-02 9.34e-01
REACTOME INTRA GOLGI TRAFFIC 43 6.11e-01 4.49e-02 9.34e-01
REACTOME JOSEPHIN DOMAIN DUBS 11 6.11e-01 8.87e-02 9.34e-01
REACTOME DEGRADATION OF DVL 56 6.11e-01 -3.93e-02 9.34e-01
REACTOME OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS 8 6.11e-01 -1.04e-01 9.34e-01
REACTOME INTEGRIN SIGNALING 27 6.12e-01 5.63e-02 9.34e-01
REACTOME ACTIVATION OF RAC1 12 6.12e-01 -8.45e-02 9.34e-01
REACTOME REGULATION OF BACH1 ACTIVITY 11 6.14e-01 8.78e-02 9.34e-01
REACTOME MTORC1 MEDIATED SIGNALLING 23 6.15e-01 -6.06e-02 9.34e-01
REACTOME HDL CLEARANCE 5 6.15e-01 -1.30e-01 9.34e-01
REACTOME GAP JUNCTION DEGRADATION 12 6.17e-01 8.34e-02 9.34e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST 18 6.18e-01 -6.80e-02 9.34e-01
REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH 62 6.19e-01 3.65e-02 9.34e-01
REACTOME HSF1 DEPENDENT TRANSACTIVATION 37 6.20e-01 -4.71e-02 9.34e-01
REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER 18 6.20e-01 6.75e-02 9.34e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE 11 6.20e-01 8.63e-02 9.34e-01
REACTOME HS GAG DEGRADATION 19 6.20e-01 -6.56e-02 9.34e-01
REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21 59 6.21e-01 3.72e-02 9.34e-01
REACTOME MAPK FAMILY SIGNALING CASCADES 314 6.21e-01 1.62e-02 9.34e-01
REACTOME PHENYLALANINE AND TYROSINE METABOLISM 11 6.21e-01 -8.60e-02 9.34e-01
REACTOME RAF ACTIVATION 33 6.22e-01 -4.96e-02 9.34e-01
REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY 5 6.22e-01 -1.27e-01 9.34e-01
REACTOME PHYSIOLOGICAL FACTORS 14 6.22e-01 7.61e-02 9.34e-01
REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB 19 6.23e-01 6.52e-02 9.34e-01
REACTOME FREE FATTY ACID RECEPTORS 5 6.23e-01 -1.27e-01 9.34e-01
REACTOME ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN 13 6.24e-01 7.86e-02 9.34e-01
REACTOME RHOBTB2 GTPASE CYCLE 22 6.24e-01 -6.04e-02 9.34e-01
REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE 11 6.24e-01 -8.54e-02 9.34e-01
REACTOME FORMATION OF INCISION COMPLEX IN GG NER 40 6.25e-01 -4.47e-02 9.34e-01
REACTOME IRAK1 RECRUITS IKK COMPLEX 12 6.25e-01 8.14e-02 9.34e-01
REACTOME SYNDECAN INTERACTIONS 26 6.25e-01 5.53e-02 9.34e-01
REACTOME CIPROFLOXACIN ADME 5 6.26e-01 1.26e-01 9.34e-01
REACTOME PHASE 0 RAPID DEPOLARISATION 31 6.26e-01 5.06e-02 9.34e-01
REACTOME CRMPS IN SEMA3A SIGNALING 15 6.27e-01 7.24e-02 9.35e-01
REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE 69 6.27e-01 -3.38e-02 9.35e-01
REACTOME RND2 GTPASE CYCLE 42 6.28e-01 4.32e-02 9.35e-01
REACTOME METABOLISM OF CARBOHYDRATES 279 6.29e-01 1.68e-02 9.35e-01
REACTOME KINESINS 59 6.30e-01 3.63e-02 9.35e-01
REACTOME NOSTRIN MEDIATED ENOS TRAFFICKING 5 6.30e-01 -1.24e-01 9.35e-01
REACTOME PHOSPHORYLATION OF EMI1 6 6.30e-01 1.13e-01 9.35e-01
REACTOME FIBRONECTIN MATRIX FORMATION 6 6.31e-01 1.13e-01 9.36e-01
REACTOME ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION 28 6.33e-01 5.21e-02 9.36e-01
REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS 16 6.35e-01 6.86e-02 9.36e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FYN 7 6.36e-01 1.03e-01 9.36e-01
REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC 28 6.36e-01 5.17e-02 9.36e-01
REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION 42 6.36e-01 4.23e-02 9.36e-01
REACTOME CHYLOMICRON CLEARANCE 5 6.36e-01 1.22e-01 9.36e-01
REACTOME INTERLEUKIN 21 SIGNALING 9 6.36e-01 9.11e-02 9.36e-01
REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA 28 6.37e-01 -5.15e-02 9.36e-01
REACTOME INSULIN PROCESSING 24 6.38e-01 5.55e-02 9.36e-01
REACTOME NUCLEAR PORE COMPLEX NPC DISASSEMBLY 36 6.38e-01 -4.53e-02 9.36e-01
REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING 13 6.38e-01 -7.53e-02 9.36e-01
REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL 12 6.38e-01 7.83e-02 9.36e-01
REACTOME SEMA3A PAK DEPENDENT AXON REPULSION 14 6.40e-01 7.23e-02 9.37e-01
REACTOME INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING 103 6.40e-01 2.67e-02 9.37e-01
REACTOME SIGNALING BY ERBB2 IN CANCER 26 6.41e-01 5.28e-02 9.37e-01
REACTOME ACTIVATION OF MATRIX METALLOPROTEINASES 30 6.42e-01 4.91e-02 9.37e-01
REACTOME TACHYKININ RECEPTORS BIND TACHYKININS 5 6.42e-01 1.20e-01 9.37e-01
REACTOME MICRORNA MIRNA BIOGENESIS 25 6.43e-01 -5.35e-02 9.38e-01
REACTOME DEFECTIVE LFNG CAUSES SCDO3 5 6.45e-01 -1.19e-01 9.39e-01
REACTOME CA2 PATHWAY 62 6.45e-01 -3.38e-02 9.39e-01
REACTOME VITAMINS 6 6.46e-01 1.08e-01 9.39e-01
REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B 24 6.47e-01 -5.40e-02 9.40e-01
REACTOME AZATHIOPRINE ADME 22 6.48e-01 -5.62e-02 9.41e-01
REACTOME KERATAN SULFATE BIOSYNTHESIS 28 6.48e-01 4.98e-02 9.41e-01
REACTOME DOWNREGULATION OF ERBB2 SIGNALING 29 6.49e-01 -4.88e-02 9.41e-01
REACTOME DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B 7 6.50e-01 9.90e-02 9.41e-01
REACTOME FORMATION OF AXIAL MESODERM 14 6.51e-01 6.99e-02 9.41e-01
REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS 19 6.51e-01 5.99e-02 9.41e-01
REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS 32 6.52e-01 -4.61e-02 9.41e-01
REACTOME ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS 24 6.53e-01 5.30e-02 9.42e-01
REACTOME COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING 38 6.54e-01 4.21e-02 9.42e-01
REACTOME MYOCLONIC EPILEPSY OF LAFORA 9 6.54e-01 8.62e-02 9.42e-01
REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC 26 6.57e-01 5.04e-02 9.43e-01
REACTOME MITOCHONDRIAL TRANSLATION 93 6.57e-01 -2.67e-02 9.43e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12 22 6.57e-01 5.46e-02 9.43e-01
REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET 8 6.58e-01 -9.05e-02 9.43e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX2 117 6.58e-01 2.37e-02 9.43e-01
REACTOME PEROXISOMAL PROTEIN IMPORT 62 6.59e-01 -3.24e-02 9.43e-01
REACTOME TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION 5 6.59e-01 -1.14e-01 9.43e-01
REACTOME SUPPRESSION OF APOPTOSIS 7 6.59e-01 -9.62e-02 9.43e-01
REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING 34 6.60e-01 4.36e-02 9.43e-01
REACTOME NUCLEAR SIGNALING BY ERBB4 32 6.60e-01 -4.49e-02 9.43e-01
REACTOME CELLULAR RESPONSE TO STARVATION 147 6.62e-01 2.09e-02 9.43e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX IN CANCER 8 6.62e-01 8.92e-02 9.43e-01
REACTOME GABA B RECEPTOR ACTIVATION 43 6.63e-01 3.84e-02 9.43e-01
REACTOME ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS 10 6.63e-01 7.96e-02 9.43e-01
REACTOME ATTACHMENT AND ENTRY 16 6.65e-01 6.26e-02 9.44e-01
REACTOME ACYL CHAIN REMODELLING OF PE 29 6.66e-01 -4.63e-02 9.44e-01
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY 33 6.67e-01 -4.32e-02 9.44e-01
REACTOME VESICLE MEDIATED TRANSPORT 642 6.68e-01 -9.91e-03 9.44e-01
REACTOME GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION 14 6.69e-01 6.60e-02 9.44e-01
REACTOME RUNX2 REGULATES CHONDROCYTE MATURATION 5 6.70e-01 -1.10e-01 9.44e-01
REACTOME LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS 19 6.70e-01 5.64e-02 9.44e-01
REACTOME SIGNALING BY TGFB FAMILY MEMBERS 119 6.71e-01 2.26e-02 9.44e-01
REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION 145 6.71e-01 -2.04e-02 9.44e-01
REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION 9 6.72e-01 -8.16e-02 9.44e-01
REACTOME CARNITINE METABOLISM 13 6.72e-01 6.77e-02 9.44e-01
REACTOME MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS 7 6.73e-01 -9.21e-02 9.44e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX 19 6.74e-01 -5.58e-02 9.44e-01
REACTOME FGFR1B LIGAND BINDING AND ACTIVATION 6 6.74e-01 -9.90e-02 9.44e-01
REACTOME SIGNAL ATTENUATION 10 6.75e-01 7.67e-02 9.44e-01
REACTOME SYNTHESIS OF GDP MANNOSE 5 6.75e-01 1.08e-01 9.44e-01
REACTOME SYNTHESIS OF PC 27 6.76e-01 4.65e-02 9.44e-01
REACTOME METABOLISM OF INGESTED SEMET SEC MESEC INTO H2SE 7 6.76e-01 -9.12e-02 9.44e-01
REACTOME EPH EPHRIN SIGNALING 90 6.76e-01 2.55e-02 9.44e-01
REACTOME IRS ACTIVATION 5 6.76e-01 -1.08e-01 9.44e-01
REACTOME PHOSPHOLIPID METABOLISM 201 6.77e-01 -1.70e-02 9.44e-01
REACTOME HEDGEHOG ON STATE 85 6.78e-01 -2.61e-02 9.44e-01
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION 81 6.78e-01 -2.67e-02 9.44e-01
REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS 21 6.78e-01 5.24e-02 9.44e-01
REACTOME AQUAPORIN MEDIATED TRANSPORT 51 6.79e-01 3.35e-02 9.44e-01
REACTOME NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10 12 6.79e-01 -6.89e-02 9.44e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES 33 6.79e-01 4.16e-02 9.44e-01
REACTOME PRE NOTCH PROCESSING IN GOLGI 18 6.81e-01 -5.59e-02 9.44e-01
REACTOME APOPTOTIC EXECUTION PHASE 49 6.82e-01 3.39e-02 9.44e-01
REACTOME MITOTIC TELOPHASE CYTOKINESIS 11 6.83e-01 -7.12e-02 9.44e-01
REACTOME DEPOLYMERISATION OF THE NUCLEAR LAMINA 14 6.83e-01 6.30e-02 9.44e-01
REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS 15 6.87e-01 -6.01e-02 9.44e-01
REACTOME G1 S SPECIFIC TRANSCRIPTION 28 6.87e-01 -4.39e-02 9.44e-01
REACTOME DISEASES OF IMMUNE SYSTEM 29 6.88e-01 -4.31e-02 9.44e-01
REACTOME TRAFFICKING OF AMPA RECEPTORS 29 6.88e-01 4.31e-02 9.44e-01
REACTOME SIGNALING BY NOTCH2 32 6.88e-01 4.10e-02 9.44e-01
REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS 101 6.88e-01 2.31e-02 9.44e-01
REACTOME SIGNALING BY KIT IN DISEASE 20 6.90e-01 5.16e-02 9.44e-01
REACTOME NEUROTRANSMITTER RELEASE CYCLE 48 6.90e-01 3.33e-02 9.44e-01
REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III 31 6.91e-01 4.12e-02 9.44e-01
REACTOME INTERLEUKIN 12 FAMILY SIGNALING 53 6.92e-01 3.15e-02 9.44e-01
REACTOME TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS 55 6.92e-01 -3.09e-02 9.44e-01
REACTOME PREVENTION OF PHAGOSOMAL LYSOSOMAL FUSION 9 6.92e-01 -7.61e-02 9.44e-01
REACTOME APEX1 INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY 7 6.93e-01 -8.62e-02 9.44e-01
REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE 24 6.93e-01 4.65e-02 9.44e-01
REACTOME ASSEMBLY OF THE HIV VIRION 16 6.94e-01 -5.67e-02 9.44e-01
REACTOME SIGNALING BY CSF3 G CSF 30 6.95e-01 4.13e-02 9.44e-01
REACTOME ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY 5 6.96e-01 1.01e-01 9.44e-01
REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX 13 6.96e-01 6.25e-02 9.44e-01
REACTOME EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION 27 6.96e-01 4.34e-02 9.44e-01
REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ 6 6.97e-01 -9.20e-02 9.44e-01
REACTOME PLATELET HOMEOSTASIS 85 6.97e-01 2.45e-02 9.44e-01
REACTOME LINOLEIC ACID LA METABOLISM 7 6.97e-01 8.50e-02 9.44e-01
REACTOME VISUAL PHOTOTRANSDUCTION 93 6.97e-01 -2.34e-02 9.44e-01
REACTOME FCERI MEDIATED MAPK ACTIVATION 32 6.98e-01 -3.97e-02 9.44e-01
REACTOME G PROTEIN BETA GAMMA SIGNALLING 30 6.98e-01 -4.09e-02 9.44e-01
REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF 17 6.98e-01 -5.43e-02 9.44e-01
REACTOME VASOPRESSIN LIKE RECEPTORS 5 6.98e-01 1.00e-01 9.44e-01
REACTOME SIGNALING BY HEDGEHOG 148 6.99e-01 1.84e-02 9.44e-01
REACTOME RUNX2 REGULATES BONE DEVELOPMENT 29 6.99e-01 4.14e-02 9.44e-01
REACTOME CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND 9 7.00e-01 7.42e-02 9.44e-01
REACTOME HEDGEHOG LIGAND BIOGENESIS 64 7.00e-01 2.78e-02 9.44e-01
REACTOME SYNAPTIC ADHESION LIKE MOLECULES 19 7.00e-01 5.10e-02 9.44e-01
REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY 14 7.02e-01 5.92e-02 9.44e-01
REACTOME MRNA CAPPING 28 7.02e-01 -4.18e-02 9.44e-01
REACTOME HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE 43 7.03e-01 -3.36e-02 9.44e-01
REACTOME METABOLISM OF STEROID HORMONES 35 7.03e-01 -3.72e-02 9.44e-01
REACTOME VEGF LIGAND RECEPTOR INTERACTIONS 7 7.03e-01 8.31e-02 9.44e-01
REACTOME RETINOID CYCLE DISEASE EVENTS 11 7.03e-01 6.63e-02 9.44e-01
REACTOME TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7 12 7.04e-01 -6.34e-02 9.44e-01
REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE 17 7.05e-01 5.30e-02 9.44e-01
REACTOME IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN 5 7.06e-01 -9.74e-02 9.44e-01
REACTOME PROTEIN LOCALIZATION 153 7.06e-01 -1.77e-02 9.44e-01
REACTOME REGULATION OF PTEN MRNA TRANSLATION 9 7.07e-01 -7.22e-02 9.44e-01
REACTOME REACTIONS SPECIFIC TO THE COMPLEX N GLYCAN SYNTHESIS PATHWAY 10 7.08e-01 -6.85e-02 9.44e-01
REACTOME DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING 61 7.08e-01 -2.77e-02 9.44e-01
REACTOME FCGR3A MEDIATED IL10 SYNTHESIS 36 7.09e-01 3.59e-02 9.44e-01
REACTOME ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS 5 7.09e-01 9.63e-02 9.44e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION TERMINATION 23 7.09e-01 -4.49e-02 9.44e-01
REACTOME N GLYCAN TRIMMING AND ELONGATION IN THE CIS GOLGI 5 7.11e-01 9.56e-02 9.46e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1 16 7.12e-01 -5.33e-02 9.46e-01
REACTOME NTRK2 ACTIVATES RAC1 5 7.12e-01 9.53e-02 9.46e-01
REACTOME G2 M DNA REPLICATION CHECKPOINT 5 7.13e-01 9.48e-02 9.46e-01
REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM 23 7.13e-01 4.42e-02 9.46e-01
REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS 123 7.14e-01 1.92e-02 9.46e-01
REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE 48 7.15e-01 -3.05e-02 9.46e-01
REACTOME DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA 77 7.17e-01 2.39e-02 9.48e-01
REACTOME REGULATION OF SIGNALING BY CBL 22 7.17e-01 4.46e-02 9.48e-01
REACTOME ORC1 REMOVAL FROM CHROMATIN 70 7.18e-01 2.49e-02 9.49e-01
REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS 91 7.19e-01 -2.18e-02 9.49e-01
REACTOME SYNTHESIS OF PE 13 7.21e-01 5.72e-02 9.49e-01
REACTOME SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA PHE 6 7.22e-01 8.40e-02 9.49e-01
REACTOME TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE 10 7.22e-01 -6.49e-02 9.49e-01
REACTOME MUSCARINIC ACETYLCHOLINE RECEPTORS 5 7.23e-01 9.17e-02 9.49e-01
REACTOME GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION 30 7.23e-01 3.74e-02 9.49e-01
REACTOME MITOCHONDRIAL TRNA AMINOACYLATION 20 7.24e-01 4.56e-02 9.49e-01
REACTOME MHC CLASS II ANTIGEN PRESENTATION 121 7.24e-01 1.86e-02 9.49e-01
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S 53 7.25e-01 2.79e-02 9.49e-01
REACTOME SMALL INTERFERING RNA SIRNA BIOGENESIS 9 7.25e-01 6.76e-02 9.49e-01
REACTOME DEFECTIVE RIPK1 MEDIATED REGULATED NECROSIS 7 7.26e-01 -7.66e-02 9.49e-01
REACTOME RHOB GTPASE CYCLE 67 7.26e-01 -2.47e-02 9.49e-01
REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX 9 7.26e-01 6.74e-02 9.49e-01
REACTOME GP1B IX V ACTIVATION SIGNALLING 11 7.27e-01 6.08e-02 9.49e-01
REACTOME DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX 83 7.27e-01 -2.21e-02 9.49e-01
REACTOME DIGESTION OF DIETARY LIPID 7 7.29e-01 7.56e-02 9.50e-01
REACTOME INTERLEUKIN 20 FAMILY SIGNALING 25 7.29e-01 -4.00e-02 9.50e-01
REACTOME CALCINEURIN ACTIVATES NFAT 9 7.31e-01 -6.63e-02 9.51e-01
REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS 299 7.33e-01 1.15e-02 9.51e-01
REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS 30 7.33e-01 3.60e-02 9.51e-01
REACTOME RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION 22 7.33e-01 4.20e-02 9.51e-01
REACTOME REGULATION OF RUNX1 EXPRESSION AND ACTIVITY 17 7.34e-01 -4.76e-02 9.51e-01
REACTOME METAL ION SLC TRANSPORTERS 23 7.35e-01 -4.08e-02 9.51e-01
REACTOME MINERALOCORTICOID BIOSYNTHESIS 6 7.35e-01 -7.97e-02 9.51e-01
REACTOME GRB7 EVENTS IN ERBB2 SIGNALING 5 7.36e-01 8.70e-02 9.51e-01
REACTOME ABACAVIR ADME 9 7.38e-01 6.43e-02 9.51e-01
REACTOME KERATAN SULFATE DEGRADATION 13 7.39e-01 -5.35e-02 9.51e-01
REACTOME FERTILIZATION 26 7.39e-01 -3.78e-02 9.51e-01
REACTOME ARACHIDONATE PRODUCTION FROM DAG 5 7.39e-01 8.59e-02 9.51e-01
REACTOME SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER 54 7.39e-01 -2.62e-02 9.51e-01
REACTOME NRCAM INTERACTIONS 6 7.40e-01 -7.82e-02 9.51e-01
REACTOME ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS 17 7.41e-01 -4.64e-02 9.51e-01
REACTOME ONCOGENE INDUCED SENESCENCE 35 7.41e-01 3.23e-02 9.51e-01
REACTOME TYPE I HEMIDESMOSOME ASSEMBLY 11 7.41e-01 5.75e-02 9.51e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS 9 7.42e-01 -6.35e-02 9.51e-01
REACTOME C TYPE LECTIN RECEPTORS CLRS 136 7.42e-01 -1.64e-02 9.51e-01
REACTOME MISCELLANEOUS SUBSTRATES 12 7.43e-01 5.46e-02 9.51e-01
REACTOME COMMON PATHWAY OF FIBRIN CLOT FORMATION 21 7.43e-01 4.13e-02 9.51e-01
REACTOME PROTON COUPLED MONOCARBOXYLATE TRANSPORT 6 7.44e-01 7.71e-02 9.51e-01
REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS 11 7.44e-01 5.69e-02 9.51e-01
REACTOME CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT 19 7.46e-01 -4.29e-02 9.51e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER 28 7.47e-01 -3.52e-02 9.51e-01
REACTOME ION CHANNEL TRANSPORT 172 7.47e-01 1.43e-02 9.51e-01
REACTOME DEFENSINS 33 7.47e-01 3.24e-02 9.51e-01
REACTOME SIGNALING BY NTRK3 TRKC 17 7.48e-01 4.50e-02 9.51e-01
REACTOME NRAGE SIGNALS DEATH THROUGH JNK 53 7.48e-01 -2.55e-02 9.51e-01
REACTOME TRAF6 MEDIATED NF KB ACTIVATION 24 7.49e-01 -3.77e-02 9.51e-01
REACTOME ESTROGEN BIOSYNTHESIS 6 7.50e-01 -7.50e-02 9.51e-01
REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM 50 7.50e-01 2.60e-02 9.51e-01
REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS 28 7.51e-01 -3.46e-02 9.51e-01
REACTOME CTLA4 INHIBITORY SIGNALING 21 7.51e-01 -4.00e-02 9.51e-01
REACTOME PURINE SALVAGE 12 7.52e-01 -5.28e-02 9.51e-01
REACTOME INTERLEUKIN 1 FAMILY SIGNALING 146 7.52e-01 1.52e-02 9.51e-01
REACTOME KSRP KHSRP BINDS AND DESTABILIZES MRNA 17 7.52e-01 -4.43e-02 9.51e-01
REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES 37 7.52e-01 -3.00e-02 9.51e-01
REACTOME FATTY ACIDS BOUND TO GPR40 FFAR1 REGULATE INSULIN SECRETION 8 7.53e-01 -6.42e-02 9.51e-01
REACTOME ALK MUTANTS BIND TKIS 12 7.54e-01 5.23e-02 9.51e-01
REACTOME SPHINGOLIPID METABOLISM 84 7.54e-01 -1.98e-02 9.51e-01
REACTOME INTEGRIN CELL SURFACE INTERACTIONS 83 7.54e-01 1.99e-02 9.51e-01
REACTOME FGFR3B LIGAND BINDING AND ACTIVATION 7 7.55e-01 6.81e-02 9.51e-01
REACTOME TOLL LIKE RECEPTOR CASCADES 158 7.56e-01 1.43e-02 9.52e-01
REACTOME PASSIVE TRANSPORT BY AQUAPORINS 13 7.57e-01 -4.95e-02 9.53e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH CDC42 19 7.59e-01 4.07e-02 9.53e-01
REACTOME FCERI MEDIATED NF KB ACTIVATION 78 7.60e-01 -2.00e-02 9.53e-01
REACTOME GDP FUCOSE BIOSYNTHESIS 6 7.60e-01 7.21e-02 9.53e-01
REACTOME RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES 16 7.60e-01 4.41e-02 9.53e-01
REACTOME HEME SIGNALING 47 7.61e-01 2.57e-02 9.54e-01
REACTOME RSK ACTIVATION 5 7.61e-01 -7.84e-02 9.54e-01
REACTOME PI3K EVENTS IN ERBB4 SIGNALING 10 7.63e-01 5.51e-02 9.54e-01
REACTOME GLUCOSE METABOLISM 90 7.63e-01 -1.84e-02 9.54e-01
REACTOME STABILIZATION OF P53 56 7.64e-01 -2.32e-02 9.54e-01
REACTOME STIMULI SENSING CHANNELS 100 7.64e-01 1.74e-02 9.54e-01
REACTOME DEFECTS IN COBALAMIN B12 METABOLISM 13 7.65e-01 4.78e-02 9.55e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH METHYLATION 19 7.67e-01 -3.94e-02 9.55e-01
REACTOME GLUCONEOGENESIS 33 7.67e-01 2.98e-02 9.55e-01
REACTOME SENSORY PERCEPTION OF TASTE 47 7.68e-01 2.48e-02 9.55e-01
REACTOME SIGNALING BY FGFR2 IIIA TM 19 7.68e-01 -3.90e-02 9.55e-01
REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS 37 7.69e-01 -2.79e-02 9.55e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST 14 7.69e-01 4.53e-02 9.55e-01
REACTOME MULTIFUNCTIONAL ANION EXCHANGERS 9 7.71e-01 -5.61e-02 9.57e-01
REACTOME SULFIDE OXIDATION TO SULFATE 6 7.73e-01 -6.81e-02 9.57e-01
REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION 31 7.73e-01 2.99e-02 9.57e-01
REACTOME INTERLEUKIN 35 SIGNALLING 12 7.74e-01 -4.80e-02 9.57e-01
REACTOME O LINKED GLYCOSYLATION 109 7.74e-01 1.59e-02 9.57e-01
REACTOME MET ACTIVATES RAS SIGNALING 11 7.75e-01 4.99e-02 9.57e-01
REACTOME POST TRANSCRIPTIONAL SILENCING BY SMALL RNAS 7 7.76e-01 -6.22e-02 9.57e-01
REACTOME TRIF MEDIATED PROGRAMMED CELL DEATH 9 7.76e-01 5.48e-02 9.57e-01
REACTOME MITOCHONDRIAL BIOGENESIS 87 7.76e-01 1.76e-02 9.57e-01
REACTOME CATION COUPLED CHLORIDE COTRANSPORTERS 7 7.79e-01 -6.13e-02 9.60e-01
REACTOME BETA CATENIN INDEPENDENT WNT SIGNALING 145 7.81e-01 -1.34e-02 9.62e-01
REACTOME REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR 11 7.82e-01 4.82e-02 9.62e-01
REACTOME TRANSCRIPTIONAL REGULATION BY MECP2 60 7.83e-01 2.05e-02 9.62e-01
REACTOME RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS 9 7.84e-01 5.28e-02 9.62e-01
REACTOME CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN 45 7.85e-01 -2.35e-02 9.62e-01
REACTOME INTEGRATION OF PROVIRUS 9 7.86e-01 5.22e-02 9.62e-01
REACTOME ENDOGENOUS STEROLS 26 7.86e-01 3.07e-02 9.62e-01
REACTOME SIGNALING BY NOTCH4 80 7.86e-01 -1.75e-02 9.62e-01
REACTOME EARLY PHASE OF HIV LIFE CYCLE 14 7.87e-01 -4.18e-02 9.62e-01
REACTOME HEDGEHOG OFF STATE 111 7.87e-01 -1.49e-02 9.62e-01
REACTOME SIGNALING BY WNT IN CANCER 32 7.87e-01 -2.76e-02 9.62e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN 13 7.87e-01 4.32e-02 9.62e-01
REACTOME FANCONI ANEMIA PATHWAY 35 7.88e-01 2.62e-02 9.63e-01
REACTOME PLATELET SENSITIZATION BY LDL 17 7.90e-01 -3.74e-02 9.63e-01
REACTOME INTERLEUKIN 37 SIGNALING 20 7.90e-01 -3.44e-02 9.63e-01
REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 73 7.93e-01 -1.77e-02 9.65e-01
REACTOME INSULIN RECEPTOR RECYCLING 29 7.93e-01 -2.81e-02 9.65e-01
REACTOME SUMOYLATION OF TRANSCRIPTION FACTORS 20 7.94e-01 -3.38e-02 9.65e-01
REACTOME SIGNALING BY ALK IN CANCER 53 7.94e-01 2.07e-02 9.65e-01
REACTOME SOS MEDIATED SIGNALLING 7 7.95e-01 5.66e-02 9.65e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1 25 7.96e-01 2.98e-02 9.65e-01
REACTOME MATURATION OF SARS COV 1 SPIKE PROTEIN 5 7.97e-01 6.64e-02 9.65e-01
REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE 10 7.97e-01 4.69e-02 9.65e-01
REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION 74 7.98e-01 1.72e-02 9.65e-01
REACTOME NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION 20 7.98e-01 3.30e-02 9.65e-01
REACTOME G ALPHA Z SIGNALLING EVENTS 48 7.98e-01 2.13e-02 9.65e-01
REACTOME NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 24 7.99e-01 -3.00e-02 9.65e-01
REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS 39 7.99e-01 -2.35e-02 9.65e-01
REACTOME TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX 10 8.02e-01 -4.58e-02 9.67e-01
REACTOMEMATURATION OF SARS COV 1 NUCLEOPROTEIN 11 8.02e-01 -4.37e-02 9.67e-01
REACTOME SIGNALING BY HIPPO 19 8.04e-01 -3.28e-02 9.68e-01
REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING 6 8.05e-01 5.82e-02 9.68e-01
REACTOME NEPHRIN FAMILY INTERACTIONS 22 8.06e-01 -3.02e-02 9.68e-01
REACTOME MYD88 INDEPENDENT TLR4 CASCADE 103 8.07e-01 1.39e-02 9.68e-01
REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR 24 8.07e-01 2.88e-02 9.68e-01
REACTOME HYALURONAN BIOSYNTHESIS AND EXPORT 5 8.07e-01 -6.30e-02 9.68e-01
REACTOME SARS COV 2 INFECTION 281 8.07e-01 -8.46e-03 9.68e-01
REACTOME DECTIN 2 FAMILY 26 8.08e-01 -2.76e-02 9.68e-01
REACTOME ANCHORING FIBRIL FORMATION 13 8.10e-01 -3.85e-02 9.69e-01
REACTOME ER TO GOLGI ANTEROGRADE TRANSPORT 152 8.11e-01 -1.13e-02 9.69e-01
REACTOME MODULATION BY MTB OF HOST IMMUNE SYSTEM 6 8.11e-01 5.65e-02 9.69e-01
REACTOME P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1 6 8.11e-01 5.63e-02 9.69e-01
REACTOME UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN 6 8.11e-01 5.63e-02 9.69e-01
REACTOME SIGNALING BY FGFR1 IN DISEASE 38 8.12e-01 2.23e-02 9.69e-01
REACTOME TRNA AMINOACYLATION 40 8.13e-01 2.16e-02 9.69e-01
REACTOME RHOA GTPASE CYCLE 142 8.15e-01 -1.14e-02 9.69e-01
REACTOME NUCLEAR ENVELOPE NE REASSEMBLY 74 8.15e-01 1.57e-02 9.69e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES 16 8.16e-01 -3.35e-02 9.69e-01
REACTOME PIWI INTERACTING RNA PIRNA BIOGENESIS 29 8.16e-01 -2.49e-02 9.69e-01
REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING 45 8.17e-01 1.99e-02 9.69e-01
REACTOME MOLYBDENUM COFACTOR BIOSYNTHESIS 6 8.17e-01 -5.45e-02 9.69e-01
REACTOME INTERFERON ALPHA BETA SIGNALING 70 8.19e-01 1.59e-02 9.69e-01
REACTOME GLUCOCORTICOID BIOSYNTHESIS 10 8.19e-01 -4.18e-02 9.69e-01
REACTOME TRANSPORT OF SMALL MOLECULES 697 8.19e-01 5.09e-03 9.69e-01
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM 688 8.19e-01 5.12e-03 9.69e-01
REACTOME ACTIVATION OF CASPASES THROUGH APOPTOSOME MEDIATED CLEAVAGE 5 8.20e-01 5.89e-02 9.69e-01
REACTOME PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1 9 8.20e-01 4.39e-02 9.69e-01
REACTOME INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE 20 8.21e-01 -2.92e-02 9.69e-01
REACTOME RUNX3 REGULATES YAP1 MEDIATED TRANSCRIPTION 8 8.21e-01 -4.61e-02 9.69e-01
REACTOME SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE 91 8.23e-01 -1.36e-02 9.69e-01
REACTOME ACYL CHAIN REMODELLING OF PI 17 8.23e-01 -3.14e-02 9.69e-01
REACTOME ACYL CHAIN REMODELING OF CL 5 8.23e-01 5.77e-02 9.69e-01
REACTOME THE ACTIVATION OF ARYLSULFATASES 8 8.25e-01 4.52e-02 9.69e-01
REACTOME ETHANOL OXIDATION 12 8.25e-01 -3.69e-02 9.69e-01
REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES 22 8.25e-01 2.72e-02 9.69e-01
REACTOME NEGATIVE REGULATION OF NOTCH4 SIGNALING 53 8.25e-01 1.75e-02 9.69e-01
REACTOME ASPARAGINE N LINKED GLYCOSYLATION 299 8.26e-01 7.38e-03 9.70e-01
REACTOME TP53 REGULATES METABOLIC GENES 81 8.27e-01 -1.40e-02 9.70e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS 7 8.27e-01 4.76e-02 9.70e-01
REACTOME DISORDERS OF TRANSMEMBRANE TRANSPORTERS 170 8.30e-01 9.57e-03 9.70e-01
REACTOME NEGATIVE REGULATION OF FLT3 15 8.30e-01 -3.20e-02 9.70e-01
REACTOME FCGR ACTIVATION 11 8.30e-01 3.73e-02 9.70e-01
REACTOME CYP2E1 REACTIONS 10 8.31e-01 3.90e-02 9.70e-01
REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT 31 8.31e-01 -2.21e-02 9.70e-01
REACTOME CRISTAE FORMATION 27 8.31e-01 2.37e-02 9.70e-01
REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS 62 8.32e-01 -1.56e-02 9.70e-01
REACTOME MAP2K AND MAPK ACTIVATION 38 8.33e-01 -1.97e-02 9.70e-01
REACTOME KETONE BODY METABOLISM 9 8.33e-01 -4.05e-02 9.70e-01
REACTOME PHASE 4 RESTING MEMBRANE POTENTIAL 19 8.34e-01 2.78e-02 9.70e-01
REACTOME COPII MEDIATED VESICLE TRANSPORT 66 8.34e-01 1.49e-02 9.70e-01
REACTOME ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM 12 8.35e-01 -3.48e-02 9.70e-01
REACTOME RAP1 SIGNALLING 16 8.42e-01 2.88e-02 9.77e-01
REACTOME BETA DEFENSINS 27 8.43e-01 -2.21e-02 9.77e-01
REACTOME ZINC TRANSPORTERS 15 8.44e-01 -2.94e-02 9.77e-01
REACTOME DRUG MEDIATED INHIBITION OF CDK4 CDK6 ACTIVITY 5 8.44e-01 -5.08e-02 9.77e-01
REACTOME POLO LIKE KINASE MEDIATED EVENTS 16 8.45e-01 -2.83e-02 9.77e-01
REACTOME IRON UPTAKE AND TRANSPORT 56 8.45e-01 -1.51e-02 9.77e-01
REACTOME ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING 23 8.47e-01 -2.33e-02 9.77e-01
REACTOME REGULATED PROTEOLYSIS OF P75NTR 11 8.47e-01 -3.35e-02 9.77e-01
REACTOME TRANSPORT AND SYNTHESIS OF PAPS 6 8.47e-01 4.54e-02 9.77e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL 14 8.48e-01 2.96e-02 9.77e-01
REACTOME FLT3 SIGNALING BY CBL MUTANTS 7 8.49e-01 -4.15e-02 9.77e-01
REACTOME ACTIVATION OF SMO 18 8.49e-01 2.58e-02 9.77e-01
REACTOME PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING 5 8.50e-01 -4.90e-02 9.77e-01
REACTOME O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS 38 8.51e-01 1.76e-02 9.77e-01
REACTOME SCAVENGING BY CLASS B RECEPTORS 6 8.52e-01 -4.41e-02 9.77e-01
REACTOME RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY 14 8.52e-01 2.87e-02 9.77e-01
REACTOME INTERFERON SIGNALING 193 8.52e-01 7.77e-03 9.77e-01
REACTOME PCP CE PATHWAY 91 8.53e-01 1.13e-02 9.77e-01
REACTOME NICOTINATE METABOLISM 31 8.53e-01 1.92e-02 9.77e-01
REACTOME NEUROTRANSMITTER CLEARANCE 9 8.53e-01 -3.56e-02 9.77e-01
REACTOME NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 25 8.53e-01 2.13e-02 9.77e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING 25 8.54e-01 -2.12e-02 9.77e-01
REACTOME INTERLEUKIN 1 SIGNALING 110 8.55e-01 -1.01e-02 9.78e-01
REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING 29 8.57e-01 1.94e-02 9.78e-01
REACTOME INWARDLY RECTIFYING K CHANNELS 35 8.57e-01 -1.76e-02 9.78e-01
REACTOME REGULATION OF KIT SIGNALING 16 8.58e-01 2.58e-02 9.78e-01
REACTOME GLYCOGEN STORAGE DISEASES 15 8.58e-01 -2.66e-02 9.78e-01
REACTOME DEFECTS IN VITAMIN AND COFACTOR METABOLISM 21 8.59e-01 -2.24e-02 9.78e-01
REACTOME INFECTION WITH MYCOBACTERIUM TUBERCULOSIS 25 8.59e-01 -2.05e-02 9.78e-01
REACTOME 2 LTR CIRCLE FORMATION 7 8.59e-01 3.87e-02 9.78e-01
REACTOME DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE 30 8.60e-01 1.86e-02 9.78e-01
REACTOME TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS 36 8.61e-01 1.69e-02 9.78e-01
REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR 19 8.61e-01 -2.32e-02 9.78e-01
REACTOME SIGNALING BY VEGF 102 8.62e-01 -9.98e-03 9.78e-01
REACTOME SARS COV 2 ACTIVATES MODULATES INNATE AND ADAPTIVE IMMUNE RESPONSES 118 8.63e-01 9.21e-03 9.78e-01
REACTOME SUPPRESSION OF PHAGOSOMAL MATURATION 13 8.64e-01 -2.75e-02 9.78e-01
REACTOME DISEASES OF DNA REPAIR 51 8.64e-01 -1.39e-02 9.78e-01
REACTOME IRE1ALPHA ACTIVATES CHAPERONES 48 8.64e-01 -1.43e-02 9.78e-01
REACTOME INLA MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS 9 8.65e-01 3.26e-02 9.79e-01
REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS 83 8.67e-01 1.07e-02 9.79e-01
REACTOME NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 22 8.69e-01 2.04e-02 9.79e-01
REACTOME TRANSLESION SYNTHESIS BY POLK 17 8.70e-01 -2.29e-02 9.79e-01
REACTOME EPHRIN SIGNALING 17 8.70e-01 2.29e-02 9.79e-01
REACTOME COPI MEDIATED ANTEROGRADE TRANSPORT 101 8.71e-01 -9.37e-03 9.79e-01
REACTOME LIPOPHAGY 9 8.71e-01 -3.13e-02 9.79e-01
REACTOME UPTAKE AND ACTIONS OF BACTERIAL TOXINS 28 8.71e-01 -1.77e-02 9.79e-01
REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS 18 8.72e-01 2.19e-02 9.79e-01
REACTOME TIGHT JUNCTION INTERACTIONS 29 8.73e-01 -1.72e-02 9.79e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS 6 8.73e-01 3.77e-02 9.79e-01
REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION 183 8.75e-01 6.76e-03 9.79e-01
REACTOME RESOLUTION OF SISTER CHROMATID COHESION 120 8.75e-01 -8.31e-03 9.79e-01
REACTOME BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA 6 8.77e-01 3.66e-02 9.79e-01
REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS 60 8.77e-01 -1.15e-02 9.79e-01
REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 44 8.79e-01 -1.32e-02 9.79e-01
REACTOME BETA OXIDATION OF PRISTANOYL COA 9 8.80e-01 2.91e-02 9.79e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS 34 8.82e-01 1.48e-02 9.79e-01
REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES 27 8.83e-01 -1.64e-02 9.79e-01
REACTOME CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY 84 8.84e-01 -9.25e-03 9.79e-01
REACTOME CLEC7A DECTIN 1 SIGNALING 97 8.84e-01 -8.58e-03 9.79e-01
REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS 15 8.85e-01 -2.16e-02 9.79e-01
REACTOME EICOSANOIDS 12 8.85e-01 2.41e-02 9.79e-01
REACTOME CELLULAR HEXOSE TRANSPORT 21 8.85e-01 -1.82e-02 9.79e-01
REACTOME INTERLEUKIN 2 FAMILY SIGNALING 40 8.86e-01 -1.31e-02 9.79e-01
REACTOME ONCOGENIC MAPK SIGNALING 79 8.87e-01 9.22e-03 9.79e-01
REACTOME VEGFR2 MEDIATED CELL PROLIFERATION 19 8.88e-01 -1.87e-02 9.79e-01
REACTOME HDL ASSEMBLY 8 8.88e-01 2.87e-02 9.79e-01
REACTOME RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION 6 8.88e-01 -3.31e-02 9.79e-01
REACTOME CDC42 GTPASE CYCLE 144 8.89e-01 6.75e-03 9.79e-01
REACTOME ARACHIDONIC ACID METABOLISM 57 8.89e-01 -1.07e-02 9.79e-01
REACTOME TOLL LIKE RECEPTOR 9 TLR9 CASCADE 100 8.89e-01 -8.08e-03 9.79e-01
REACTOME LIPID PARTICLE ORGANIZATION 6 8.89e-01 -3.28e-02 9.79e-01
REACTOME RECEPTOR MEDIATED MITOPHAGY 10 8.91e-01 2.50e-02 9.79e-01
REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING 26 8.91e-01 1.55e-02 9.79e-01
REACTOME BIOLOGICAL OXIDATIONS 210 8.91e-01 5.47e-03 9.79e-01
REACTOME RHOQ GTPASE CYCLE 57 8.92e-01 -1.04e-02 9.79e-01
REACTOME GLYCOLYSIS 70 8.92e-01 9.37e-03 9.79e-01
REACTOME RAS PROCESSING 22 8.92e-01 -1.67e-02 9.79e-01
REACTOME BUDDING AND MATURATION OF HIV VIRION 28 8.94e-01 1.46e-02 9.79e-01
REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION 160 8.94e-01 6.08e-03 9.79e-01
REACTOME RNA POLYMERASE III CHAIN ELONGATION 18 8.96e-01 1.78e-02 9.79e-01
REACTOME SYNTHESIS OF UDP N ACETYL GLUCOSAMINE 7 8.96e-01 2.86e-02 9.79e-01
REACTOME COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC 98 8.96e-01 -7.62e-03 9.79e-01
REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL 13 8.97e-01 2.08e-02 9.79e-01
REACTOME HISTIDINE CATABOLISM 8 8.97e-01 -2.65e-02 9.79e-01
REACTOME RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR 19 8.97e-01 1.72e-02 9.79e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH CDK5 6 8.99e-01 -2.99e-02 9.79e-01
REACTOME SIGNAL TRANSDUCTION BY L1 20 9.00e-01 1.63e-02 9.79e-01
REACTOME DISEASES OF BASE EXCISION REPAIR 5 9.00e-01 -3.24e-02 9.79e-01
REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING 30 9.00e-01 1.32e-02 9.79e-01
REACTOME CYTOCHROME C MEDIATED APOPTOTIC RESPONSE 12 9.00e-01 -2.09e-02 9.79e-01
REACTOME INITIAL TRIGGERING OF COMPLEMENT 21 9.01e-01 1.57e-02 9.79e-01
REACTOME FCERI MEDIATED CA 2 MOBILIZATION 30 9.01e-01 -1.31e-02 9.79e-01
REACTOME EXTRA NUCLEAR ESTROGEN SIGNALING 74 9.02e-01 8.28e-03 9.79e-01
REACTOME RAS SIGNALING DOWNSTREAM OF NF1 LOSS OF FUNCTION VARIANTS 7 9.03e-01 2.67e-02 9.79e-01
REACTOME SIGNALING BY RNF43 MUTANTS 8 9.04e-01 -2.46e-02 9.79e-01
REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS 5 9.04e-01 3.11e-02 9.79e-01
REACTOME REGULATION OF TP53 EXPRESSION AND DEGRADATION 37 9.04e-01 1.14e-02 9.79e-01
REACTOME METABOLISM OF VITAMINS AND COFACTORS 185 9.05e-01 5.10e-03 9.79e-01
REACTOME CD22 MEDIATED BCR REGULATION 5 9.06e-01 3.06e-02 9.79e-01
REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION 9 9.06e-01 -2.27e-02 9.79e-01
REACTOME RHOJ GTPASE CYCLE 51 9.07e-01 9.46e-03 9.79e-01
REACTOME MITOCHONDRIAL PROTEIN IMPORT 58 9.08e-01 8.82e-03 9.79e-01
REACTOME METHYLATION 14 9.08e-01 -1.79e-02 9.79e-01
REACTOME MET PROMOTES CELL MOTILITY 41 9.08e-01 -1.04e-02 9.79e-01
REACTOME NUCLEAR EVENTS MEDIATED BY NFE2L2 77 9.09e-01 7.56e-03 9.79e-01
REACTOME INTERLEUKIN RECEPTOR SHC SIGNALING 24 9.09e-01 1.35e-02 9.79e-01
REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION 20 9.10e-01 -1.47e-02 9.79e-01
REACTOME DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS 14 9.10e-01 -1.75e-02 9.79e-01
REACTOME SARS COV 1 INFECTION 136 9.10e-01 5.62e-03 9.79e-01
REACTOME RHO GTPASE CYCLE 423 9.10e-01 -3.20e-03 9.79e-01
REACTOME DCC MEDIATED ATTRACTIVE SIGNALING 14 9.11e-01 1.72e-02 9.79e-01
REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS 63 9.12e-01 -8.08e-03 9.79e-01
REACTOME INACTIVATION OF CSF3 G CSF SIGNALING 25 9.12e-01 -1.28e-02 9.79e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE 74 9.12e-01 -7.44e-03 9.79e-01
REACTOME KERATINIZATION 210 9.12e-01 4.42e-03 9.79e-01
REACTOME ORGANIC CATION TRANSPORT 10 9.13e-01 2.00e-02 9.79e-01
REACTOME GLYCOGEN SYNTHESIS 13 9.14e-01 1.73e-02 9.79e-01
REACTOME SYNTHESIS OF 12 EICOSATETRAENOIC ACID DERIVATIVES 7 9.14e-01 -2.36e-02 9.79e-01
REACTOME FORMATION OF PARAXIAL MESODERM 22 9.14e-01 -1.33e-02 9.79e-01
REACTOME INTEGRATION OF ENERGY METABOLISM 105 9.14e-01 6.07e-03 9.79e-01
REACTOME REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS 11 9.15e-01 1.85e-02 9.79e-01
REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS 188 9.15e-01 4.50e-03 9.79e-01
REACTOME SIGNALING BY NOTCH3 48 9.17e-01 8.65e-03 9.80e-01
REACTOME BICARBONATE TRANSPORTERS 10 9.18e-01 1.89e-02 9.80e-01
REACTOME PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS 21 9.18e-01 -1.30e-02 9.80e-01
REACTOME NADE MODULATES DEATH SIGNALLING 5 9.18e-01 2.65e-02 9.80e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA 27 9.20e-01 1.12e-02 9.80e-01
REACTOME SULFUR AMINO ACID METABOLISM 27 9.20e-01 -1.11e-02 9.81e-01
REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION 19 9.21e-01 1.31e-02 9.81e-01
REACTOME CREB PHOSPHORYLATION 6 9.22e-01 -2.31e-02 9.81e-01
REACTOME INTERLEUKIN 15 SIGNALING 13 9.22e-01 1.56e-02 9.81e-01
REACTOME CHYLOMICRON ASSEMBLY 10 9.23e-01 -1.76e-02 9.81e-01
REACTOME CLEC7A INFLAMMASOME PATHWAY 6 9.25e-01 2.23e-02 9.82e-01
REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX 8 9.25e-01 1.92e-02 9.82e-01
REACTOME PARASITE INFECTION 57 9.28e-01 -6.88e-03 9.85e-01
REACTOME VITAMIN B1 THIAMIN METABOLISM 5 9.29e-01 -2.30e-02 9.85e-01
REACTOME RHO GTPASES ACTIVATE KTN1 11 9.31e-01 -1.51e-02 9.85e-01
REACTOME SIGNALING BY FGFR IN DISEASE 62 9.31e-01 6.36e-03 9.85e-01
REACTOME ROLE OF ABL IN ROBO SLIT SIGNALING 8 9.31e-01 1.76e-02 9.85e-01
REACTOME ESTABLISHMENT OF SISTER CHROMATID COHESION 9 9.32e-01 -1.65e-02 9.85e-01
REACTOME RHOH GTPASE CYCLE 37 9.32e-01 -8.08e-03 9.85e-01
REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS 18 9.33e-01 1.15e-02 9.85e-01
REACTOME CD28 DEPENDENT VAV1 PATHWAY 11 9.33e-01 1.46e-02 9.85e-01
REACTOME G ALPHA 12 13 SIGNALLING EVENTS 74 9.36e-01 -5.39e-03 9.85e-01
REACTOME RHOBTB1 GTPASE CYCLE 22 9.37e-01 -9.80e-03 9.85e-01
REACTOME SARS COV 2 HOST INTERACTIONS 191 9.37e-01 3.31e-03 9.85e-01
REACTOME SYNTHESIS OF KETONE BODIES 8 9.37e-01 -1.61e-02 9.85e-01
REACTOME MASTL FACILITATES MITOTIC PROGRESSION 10 9.37e-01 1.44e-02 9.85e-01
REACTOME RECYCLING OF EIF2 GDP 7 9.37e-01 -1.72e-02 9.85e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION TERMINATION 30 9.38e-01 -8.25e-03 9.85e-01
REACTOME APOPTOSIS 173 9.38e-01 3.44e-03 9.85e-01
REACTOME ERBB2 REGULATES CELL MOTILITY 15 9.41e-01 1.10e-02 9.87e-01
REACTOME NEGATIVE REGULATION OF MAPK PATHWAY 41 9.41e-01 6.63e-03 9.87e-01
REACTOME PREGNENOLONE BIOSYNTHESIS 12 9.42e-01 1.20e-02 9.87e-01
REACTOME ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA 9 9.43e-01 1.38e-02 9.87e-01
REACTOME BILE ACID AND BILE SALT METABOLISM 45 9.44e-01 6.03e-03 9.87e-01
REACTOME FRUCTOSE CATABOLISM 5 9.46e-01 1.76e-02 9.87e-01
REACTOME RORA ACTIVATES GENE EXPRESSION 17 9.46e-01 -9.53e-03 9.87e-01
REACTOME SARS COV 1 HOST INTERACTIONS 92 9.46e-01 -4.09e-03 9.87e-01
REACTOME DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1 9 9.46e-01 1.30e-02 9.87e-01
REACTOME PEROXISOMAL LIPID METABOLISM 28 9.47e-01 -7.31e-03 9.87e-01
REACTOME ASPARTATE AND ASPARAGINE METABOLISM 11 9.47e-01 -1.15e-02 9.87e-01
REACTOME REGULATION OF PTEN LOCALIZATION 8 9.47e-01 1.35e-02 9.87e-01
REACTOME AGGREPHAGY 42 9.50e-01 5.61e-03 9.87e-01
REACTOME REGULATION OF RAS BY GAPS 66 9.51e-01 -4.40e-03 9.87e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K 12 9.51e-01 -1.03e-02 9.87e-01
REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES 7 9.51e-01 1.34e-02 9.87e-01
REACTOME DEGRADATION OF GLI1 BY THE PROTEASOME 59 9.51e-01 4.63e-03 9.87e-01
REACTOME BETA CATENIN PHOSPHORYLATION CASCADE 16 9.51e-01 -8.83e-03 9.87e-01
REACTOME EARLY SARS COV 2 INFECTION EVENTS 34 9.52e-01 -6.02e-03 9.87e-01
REACTOME FOLDING OF ACTIN BY CCT TRIC 10 9.52e-01 -1.09e-02 9.87e-01
REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY 29 9.53e-01 6.32e-03 9.87e-01
REACTOME SCAVENGING OF HEME FROM PLASMA 13 9.54e-01 9.16e-03 9.88e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY DVL INTERACTING PROTEINS 5 9.55e-01 1.47e-02 9.88e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS 9 9.56e-01 -1.05e-02 9.88e-01
REACTOME CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2 11 9.57e-01 -9.39e-03 9.88e-01
REACTOME WNT MEDIATED ACTIVATION OF DVL 8 9.57e-01 1.10e-02 9.88e-01
REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS 45 9.57e-01 4.61e-03 9.88e-01
REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY 46 9.58e-01 4.47e-03 9.88e-01
REACTOME STAT3 NUCLEAR EVENTS DOWNSTREAM OF ALK SIGNALING 9 9.59e-01 9.82e-03 9.89e-01
REACTOME RESPONSE OF MTB TO PHAGOCYTOSIS 22 9.61e-01 -6.01e-03 9.90e-01
REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS 418 9.62e-01 1.36e-03 9.90e-01
REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 11 9.63e-01 -8.07e-03 9.90e-01
REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS 5 9.63e-01 1.19e-02 9.90e-01
REACTOME G1 S DNA DAMAGE CHECKPOINTS 67 9.64e-01 3.20e-03 9.90e-01
REACTOME ELASTIC FIBRE FORMATION 44 9.64e-01 -3.90e-03 9.90e-01
REACTOME REGULATION OF NPAS4 MRNA TRANSLATION 9 9.64e-01 8.62e-03 9.90e-01
REACTOME NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 11 9.66e-01 -7.44e-03 9.90e-01
REACTOME PLATELET AGGREGATION PLUG FORMATION 39 9.66e-01 3.95e-03 9.90e-01
REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 54 9.66e-01 3.33e-03 9.90e-01
REACTOME MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION 15 9.68e-01 -5.99e-03 9.91e-01
REACTOME FORMATION OF APOPTOSOME 10 9.69e-01 7.04e-03 9.91e-01
REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4 33 9.70e-01 3.83e-03 9.91e-01
REACTOME BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA 17 9.72e-01 4.93e-03 9.93e-01
REACTOME NUCLEAR ENVELOPE BREAKDOWN 52 9.72e-01 -2.79e-03 9.93e-01
REACTOME UNWINDING OF DNA 12 9.73e-01 5.55e-03 9.93e-01
REACTOME REGULATION OF IFNG SIGNALING 14 9.75e-01 4.92e-03 9.94e-01
REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS 86 9.76e-01 1.89e-03 9.94e-01
REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY 10 9.77e-01 -5.35e-03 9.94e-01
REACTOME FGFR2B LIGAND BINDING AND ACTIVATION 10 9.77e-01 -5.32e-03 9.94e-01
REACTOME SPERM MOTILITY AND TAXES 9 9.77e-01 -5.50e-03 9.94e-01
REACTOME ALPHA OXIDATION OF PHYTANATE 6 9.78e-01 6.44e-03 9.94e-01
REACTOME RHO GTPASES ACTIVATE ROCKS 19 9.79e-01 -3.50e-03 9.94e-01
REACTOME ECM PROTEOGLYCANS 73 9.79e-01 -1.74e-03 9.94e-01
REACTOME ACETYLCHOLINE REGULATES INSULIN SECRETION 10 9.80e-01 4.60e-03 9.94e-01
REACTOME MATURATION OF SARS COV 2 SPIKE PROTEIN 35 9.81e-01 -2.36e-03 9.95e-01
REACTOME TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT 18 9.83e-01 2.83e-03 9.95e-01
REACTOME APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS 87 9.84e-01 1.26e-03 9.95e-01
REACTOME ION TRANSPORT BY P TYPE ATPASES 51 9.84e-01 -1.60e-03 9.95e-01
REACTOME MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS 17 9.84e-01 -2.76e-03 9.95e-01
REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS 11 9.84e-01 3.41e-03 9.95e-01
REACTOME CYTOSOLIC TRNA AMINOACYLATION 22 9.86e-01 2.14e-03 9.96e-01
REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX 39 9.86e-01 1.59e-03 9.96e-01
REACTOME SIGNALING BY NOTCH1 69 9.88e-01 -1.07e-03 9.97e-01
REACTOME TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY 16 9.89e-01 -2.06e-03 9.97e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY 19 9.90e-01 -1.72e-03 9.97e-01
REACTOME SARS COV 2 MODULATES AUTOPHAGY 11 9.90e-01 2.24e-03 9.97e-01
REACTOME CELLULAR RESPONSE TO HYPOXIA 74 9.93e-01 6.31e-04 9.99e-01
REACTOME SIALIC ACID METABOLISM 33 9.94e-01 -7.36e-04 9.99e-01
REACTOME HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR IN THE PRESENCE OF LIGAND 55 9.95e-01 -5.20e-04 9.99e-01
REACTOME THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT 77 9.95e-01 4.23e-04 9.99e-01
REACTOME METABOLISM OF COFACTORS 19 9.95e-01 7.61e-04 9.99e-01
REACTOME PLATELET CALCIUM HOMEOSTASIS 27 9.96e-01 -5.90e-04 9.99e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION 89 9.97e-01 2.34e-04 9.99e-01
REACTOME COBALAMIN CBL METABOLISM 7 9.98e-01 -5.06e-04 9.99e-01
REACTOME RECYCLING OF BILE ACIDS AND SALTS 18 9.98e-01 -2.68e-04 9.99e-01
REACTOME LOSS OF FUNCTION OF SMAD2 3 IN CANCER 7 9.98e-01 4.16e-04 9.99e-01
REACTOME RHO GTPASES ACTIVATE FORMINS 136 9.99e-01 6.59e-05 9.99e-01
REACTOME TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS 52 9.99e-01 7.36e-05 9.99e-01


Detailed Gene set reports



REACTOME_CHROMATIN_MODIFYING_ENZYMES

REACTOME_CHROMATIN_MODIFYING_ENZYMES
558
set REACTOME_CHROMATIN_MODIFYING_ENZYMES
setSize 252
pANOVA 1.83e-09
s.dist -0.22
p.adjustANOVA 3.01e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC3 -11072.0
KMT2B -11022.0
PRDM9 -10877.0
H3C3 -10752.0
H3C6 -10696.0
KMT2D -10466.0
H2BC26 -10276.0
PADI6 -10215.0
H2AC7 -10188.5
H2BC7 -10188.5
H2AC25 -10089.0
H2AC20 -10070.0
H2AC14 -9995.0
ARID2 -9935.0
JAK2 -9917.0
HMG20B -9890.0
CLOCK -9787.0
TADA1 -9781.0
H3C4 -9701.0
SUPT20H -9673.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC3 -11072.0
KMT2B -11022.0
PRDM9 -10877.0
H3C3 -10752.0
H3C6 -10696.0
KMT2D -10466.0
H2BC26 -10276.0
PADI6 -10215.0
H2AC7 -10188.5
H2BC7 -10188.5
H2AC25 -10089.0
H2AC20 -10070.0
H2AC14 -9995.0
ARID2 -9935.0
JAK2 -9917.0
HMG20B -9890.0
CLOCK -9787.0
TADA1 -9781.0
H3C4 -9701.0
SUPT20H -9673.0
PHF20 -9613.0
DOT1L -9559.0
SAP18 -9501.0
BRPF1 -9476.0
SMARCA4 -9405.0
DR1 -9170.0
TRRAP -9080.0
PHF2 -9076.0
H2AC18 -9031.5
H2AC19 -9031.5
HDAC10 -8983.0
EP400 -8902.0
RELA -8787.0
NSD3 -8764.0
TAF6L -8732.0
ING5 -8414.0
HAT1 -8375.0
SMYD2 -8343.0
H3C1 -8260.0
NCOA1 -8254.0
H2BC14 -8236.0
SMARCB1 -8171.0
ING3 -8081.0
H2AC21 -8042.0
GPS2 -8018.0
H2AC8 -8007.0
KMT5C -8004.0
MCRS1 -7889.0
PRDM16 -7839.0
KAT6A -7816.0
H4C1 -7768.0
H2AX -7754.0
PRMT6 -7699.0
H2BC8 -7687.0
ARID1A -7610.0
RUVBL1 -7570.0
SETD3 -7548.0
WDR5 -7515.0
H2BC21 -7485.0
H3C11 -7455.0
KANSL1 -7445.0
EP300 -7432.0
PADI1 -7287.0
PAX3 -7192.0
ATF7IP -7154.0
GATAD2A -7114.0
TADA2A -7095.0
KAT2A -7092.0
KMT2E -7079.0
BRMS1 -7026.0
NSD2 -6909.0
TAF5L -6843.0
ARID1B -6832.0
BRD1 -6812.0
EHMT2 -6790.0
MTA1 -6546.0
SETDB1 -6393.0
SUDS3 -6371.0
HDAC1 -6364.0
ATXN7L3 -6350.0
ATXN7 -6164.0
NCOR1 -6111.0
H2AC1 -6019.0
MSL1 -5927.0
BRWD1 -5819.0
SGF29 -5801.0
KAT2B -5792.0
KDM3A -5713.0
KDM4B -5696.0
CHD3 -5673.0
ACTL6A -5563.0
KAT5 -5557.0
EHMT1 -5545.0
REST -5458.0
H4C4 -5408.0
H2BC1 -5406.0
ELP4 -5318.0
MBD3 -5200.0
RBBP5 -5151.0
NFKB2 -5123.0
SETD1A -5060.0
H4C9 -5033.0
CARM1 -5002.0
USP22 -4895.0
EZH2 -4861.0
SMARCD2 -4823.0
PRMT7 -4573.0
SUPT7L -4565.0
ELP6 -4402.0
ELP2 -4072.0
RCOR1 -3905.0
SUPT3H -3886.0
H4C3 -3847.0
PRMT1 -3846.0
BRD8 -3799.0
KDM4A -3560.0
KANSL2 -3490.0
ARID4B -3376.0
H2AC15 -3334.0
RIOX2 -3314.0
AEBP2 -3220.0
ZZZ3 -3077.0
KDM1B -2950.0
PBRM1 -2949.0
NCOA2 -2942.0
JADE2 -2872.0
TAF12 -2722.0
NFKB1 -2712.0
HDAC3 -2692.0
MSL2 -2645.0
H4C6 -2615.0
CCND1 -2612.0
KAT7 -2611.0
TBL1XR1 -2551.0
ENY2 -2379.0
CDK4 -2328.0
MRGBP -2288.0
KDM4C -2272.0
TAF9 -2271.0
KMT2C -2208.0
H4C12 -2167.0
ASH1L -2144.0
CREBBP -2076.0
KMT5B -2034.0
KDM1A -2016.0
YEATS2 -1826.0
H2BC12 -1743.0
KAT6B -1722.0
KANSL3 -1641.0
PRMT5 -1468.0
MEAF6 -1421.0
SETD2 -1362.0
H4C16 -1250.0
NSD1 -1249.0
H2AC4 -1132.0
SMARCC1 -1105.0
H3C8 -1035.0
ACTL6B -917.0
MORF4L1 -844.0
VPS72 -813.0
BRPF3 -745.0
KDM3B -722.0
SAP30 -541.0
H4C11 -494.0
DNMT3A -476.0
SETD7 -399.0
KDM4D -398.0
SMYD3 -276.0
H2BC11 -106.0
H2BC9 36.5
H3C7 36.5
ELP1 70.0
RUVBL2 158.0
WDR77 169.0
COPRS 178.0
H2AZ2 203.0
KDM2A 207.0
SMARCC2 236.0
KDM6B 458.0
H4C5 481.0
TADA3 523.0
RPS2 787.0
SETDB2 842.0
KDM5B 885.0
SUV39H2 888.0
SAP30L 1031.0
PADI3 1044.0
CHD4 1053.0
H2BC10 1117.0
EED 1128.0
KMT2A 1144.0
MTA3 1224.0
ING4 1305.0
ARID5B 1398.0
SAP130 1467.0
H2AJ 1474.0
EPC1 1524.0
SETD1B 1562.0
H2AC12 1565.0
H2AC17 1568.0
PHF21A 1752.0
PRMT3 1890.0
MECOM 1933.0
TAF10 1944.0
H4C2 2031.0
KDM5A 2256.0
KMT5A 2285.0
MTA2 2290.0
ELP5 2331.0
SUZ12 2417.0
SMARCE1 2503.0
DPY30 2505.0
H4C13 2526.0
H2BC17 2583.0
ELP3 2752.0
ASH2L 2779.0
GATAD2B 3828.0
H2BC15 3952.0
SMARCD1 4142.0
H2BC5 4154.0
H3C2 4334.0
YEATS4 4563.0
JADE1 4583.0
KDM2B 4752.0
NCOR2 4797.0
ARID4A 4800.0
KDM7A 5013.0
JMJD6 5033.0
DMAP1 5311.0
RBBP4 5414.0
H2AC11 5446.0
H2AC13 5645.0
H2BC6 5880.0
SMARCA2 6082.0
MBIP 6137.0
PADI4 6310.0
TADA2B 6406.0
HDAC2 6519.0
H2AC16 6664.0
SETD6 6705.0
H4C8 6856.0
PADI2 6893.0
ACTB 7403.0
ATF2 8104.0
H3C10 8230.0
SMARCD3 8563.0
KAT8 8643.0
H2AZ1 8703.0
H2BC13 8750.0
H2AC6 9114.0
H2BC4 9890.0
H3C12 10509.0


REACTOME_NEUTROPHIL_DEGRANULATION

REACTOME_NEUTROPHIL_DEGRANULATION
1053
set REACTOME_NEUTROPHIL_DEGRANULATION
setSize 460
pANOVA 1.07e-06
s.dist 0.133
p.adjustANOVA 0.000876



Top enriched genes

Top 20 genes
GeneID Gene Rank
FOLR3 10725
RNASE3 10721
S100A8 10716
AZU1 10713
MPO 10712
FCGR3B 10667
S100A9 10644
RNASE2 10626
CTSG 10578
PGLYRP1 10543
CLEC4D 10522
LRG1 10514
LILRB2 10513
SLPI 10489
CEACAM6 10480
OLR1 10444
FCER1G 10439
CXCR2 10434
SERPINA1 10426
TYROBP 10391

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FOLR3 10725
RNASE3 10721
S100A8 10716
AZU1 10713
MPO 10712
FCGR3B 10667
S100A9 10644
RNASE2 10626
CTSG 10578
PGLYRP1 10543
CLEC4D 10522
LRG1 10514
LILRB2 10513
SLPI 10489
CEACAM6 10480
OLR1 10444
FCER1G 10439
CXCR2 10434
SERPINA1 10426
TYROBP 10391
PRTN3 10385
RETN 10341
CD93 10340
CD177 10334
HSPA6 10330
PPBP 10229
HP 10213
C5AR1 10139
LCN2 10128
CDA 10120
CD68 10075
PYCARD 10029
PLAU 10020
DEFA4 10012
LYZ 9989
VAT1 9975
ADGRG3 9960
SIRPB1 9940
ELANE 9879
CEACAM3 9834
FGR 9815
PTPRJ 9807
DOK3 9765
GSN 9762
MANBA 9699
MNDA 9653
GMFG 9600
FABP5 9533
LILRB3 9444
RAB3D 9430
MS4A3 9409
SERPINB1 9378
GHDC 9327
FCN1 9254
GNS 9239
PLD1 9219
TARM1 9187
OSCAR 9164
GDI2 9120
CD59 9095
TNFRSF1B 9070
SLC11A1 9061
PRKCD 9030
AGPAT2 8977
VNN1 8952
ARMC8 8951
CD33 8896
GLIPR1 8890
EPX 8827
GSTP1 8743
SERPINA3 8709
SVIP 8627
PSMB7 8601
CTSZ 8592
CTSD 8552
SERPINB12 8496
CFD 8484
STING1 8449
STBD1 8431
SLC27A2 8380
PRDX6 8288
AMPD3 8287
HLA-B 8040
MCEMP1 8016
FLG2 7995
SIRPA 7986
DOCK2 7955
RAB37 7881
VAMP8 7854
NRAS 7853
FCAR 7827
HSPA1B 7790
CAP1 7661
ACTR2 7628
CKAP4 7580
PGM2 7555
S100A11 7549
ADAM8 7522
RHOG 7516
S100A12 7414
SLCO4C1 7410
HK3 7384
SERPINB10 7381
SIGLEC14 7361
PYGL 7358
DSN1 7300
NAPRT 7277
S100P 7227
TXNDC5 7136
CLEC5A 7132
APRT 7122
CPNE3 7057
ADGRE3 6925
PADI2 6893
HEXB 6891
PSMA2 6848
C1orf35 6781
RAB27A 6776
PSMC2 6774
AHSG 6766
CTSH 6597
DGAT1 6540
CTSA 6522
NPC2 6319
P2RX1 6296
GPR84 6200
PRSS3 6196
LPCAT1 6099
ACP3 6085
NHLRC3 6075
KCMF1 5902
C6orf120 5791
CTSB 5709
SDCBP 5661
TMC6 5653
CEP290 5498
CREG1 5490
LTA4H 5394
CD300A 5357
IST1 5285
COPB1 5241
LILRA3 5202
CLEC12A 5182
ATP6V0A1 5145
RAB5B 5075
CXCL1 5052
SLC15A4 4985
CD14 4930
CHRNB4 4883
B2M 4789
EEF1A1 4767
PSEN1 4717
GRN 4711
DNAJC3 4670
CHI3L1 4664
DIAPH1 4574
DEGS1 4515
PNP 4503
ALDOC 4500
RAB31 4466
DSC1 4411
CD58 4398
LGALS3 4394
CRISPLD2 4380
SLC2A5 4344
CR1 4271
ACTR10 4211
PSMD14 4205
DNAJC5 4193
SRP14 4144
PKM 4085
VCL 4001
CXCR1 3976
BIN2 3961
IRAG2 3898
TRAPPC1 3892
HVCN1 3890
ALDH3B1 3886
ERP44 3874
COTL1 3805
PLAUR 3697
SLC2A3 3614
TRPM2 3505
CTSC 3493
PRG2 3478
GM2A 3436
HSP90AB1 3410
B4GALT1 3375
PLAC8 3358
GYG1 3255
IDH1 3185
NME2 3121
RAB5C 3065
SNAP23 3006
CYSTM1 2997
DDOST 2960
CTSS 2926
HPSE 2900
TOM1 2879
TNFAIP6 2840
ALOX5 2826
PSMD3 2823
IMPDH1 2807
CD53 2786
TMEM30A 2611
ARG1 2580
ENPP4 2544
DBNL 2524
NBEAL2 2437
RAP2B 2209
BST1 2133
ATP6V1D 2105
MGAM 2092
KPNB1 1994
CD63 1972
CCT8 1966
ROCK1 1951
PLEKHO2 1936
NIT2 1889
DERA 1835
PRCP 1792
SELL 1669
FTH1 1606
ADAM10 1586
PKP1 1480
ANPEP 1479
PA2G4 1445
SCAMP1 1346
RAP1A 1344
MAPK1 1304
MME 1300
TUBB 1258
ARSA 1202
ILF2 1069
FTL 1068
CAB39 1047
TUBB4B 988
PIGR 975
ITGAL 937
APAF1 883
PPIA 857
ORM2 852
ALDOA 834
LAMTOR1 825
RAB24 797
STK10 785
GOLGA7 749
IQGAP2 694
MMP8 657
FPR2 615
STOM 433
XRCC5 416
NFASC 228
SNAP25 147
ORMDL3 131
PTPRB 86
TTR 46
CD44 39
DYNLL1 -62
HLA-C -81
NFAM1 -128
TIMP2 -171
DNAJC13 -185
PTX3 -202
CSNK2B -255
ANO6 -263
FCGR2A -286
HEBP2 -296
STK11IP -300
PSMD11 -313
PYGB -354
GCA -361
AGL -488
FGL2 -497
ATG7 -503
LAMTOR2 -585
ABCA13 -627
LAMTOR3 -634
PSMC3 -685
PGAM1 -749
RAP1B -756
MMP9 -947
TICAM2 -992
HSPA1A -1041
VAPA -1067
CNN2 -1099
CST3 -1143
CHIT1 -1164
BPI -1180
ITGB2 -1311
ARSB -1319
ATP6V0C -1338
PSMB1 -1423
RAB18 -1428
PSAP -1493
GALNS -1647
A1BG -1703
CD47 -1733
RHOA -1807
RAB4B -1825
ASAH1 -1920
RAB14 -1976
CLEC4C -1988
UNC13D -1999
RAB7A -2015
TMBIM1 -2041
VPS35L -2048
RHOF -2055
RAC1 -2129
PTPRN2 -2185
C3AR1 -2289
ARHGAP9 -2314
TOLLIP -2369
LAIR1 -2377
HGSNAT -2393
SERPINB3 -2398
MAPK14 -2455
GGH -2458
DSP -2574
ATP8B4 -2580
APEH -2657
NFKB1 -2712
CRISP3 -2784
DYNC1LI1 -2789
RAB10 -2993
PDXK -3032
HSPA8 -3316
NCSTN -3348
CMTM6 -3468
AOC1 -3501
SIGLEC5 -3588
MLEC -3600
FAF2 -3623
CAT -3737
C3 -3747
BRI3 -3763
PTAFR -3776
UBR4 -3791
LTF -3815
RAB44 -3858
TSPAN14 -3910
SIGLEC9 -3918
ARL8A -3953
IGF2R -3975
CPNE1 -4042
PSMD6 -4053
PAFAH1B2 -4096
IQGAP1 -4119
OLFM4 -4173
PSMA5 -4249
ATP8A1 -4261
MGST1 -4271
AP2A2 -4338
HLA-A -4407
TCN1 -4471
CCT2 -4530
HSP90AA1 -4552
CD36 -4590
CRACR2A -4598
GPI -4641
CAND1 -4642
NCKAP1L -4688
PSMD7 -4693
LAMP1 -4736
AP1M1 -4825
CEACAM1 -5012
ANXA2 -5015
ACLY -5075
CYBA -5153
DSG1 -5168
GSDMD -5202
PTPRC -5207
OSTF1 -5341
HRNR -5399
CD55 -5455
QPCT -5459
MMP25 -5470
ADGRE5 -5547
TCIRG1 -5717
ITGAV -5756
HBB -5861
NEU1 -5862
QSOX1 -5900
CPPED1 -5911
ATP11B -5940
TLR2 -5952
CAPN1 -5964
FUCA1 -5987
SYNGR1 -6073
YPEL5 -6106
GUSB -6108
HMGB1 -6150
CAMP -6161
MVP -6204
ATAD3B -6206
FRK -6247
SLC44A2 -6309
CYFIP1 -6404
CYB5R3 -6599
ITGAX -6637
MIF -6670
FUCA2 -6682
LRRC7 -6747
PTPN6 -6907
PGM1 -7330
SNAP29 -7345
BST2 -7427
DYNC1H1 -7456
PTGES2 -7468
JUP -7518
ATP11A -7539
CEACAM8 -7554
DYNLT1 -7568
PRG3 -7711
PSMD1 -7718
COMMD9 -7840
AGA -7880
PDAP1 -7930
PECAM1 -7976
VCP -7977
ACTR1B -7982
KCNAB2 -8207
TMEM63A -8360
ADA2 -8412
ARPC5 -8477
MAN2B1 -8484
DPP7 -8585
CANT1 -8600
IMPDH2 -8655
RAB3A -8669
PSMD12 -8730
ITGAM -8862
GLB1 -8890
SERPINB6 -8893
ARHGAP45 -9083
PSMD13 -9136
ACAA1 -9174
COMMD3 -9186
CDK13 -9252
SURF4 -9307
XRCC6 -9311
ALAD -9384
EEF2 -9480
RAB6A -9519
ORM1 -9543
GAA -9671
HMOX2 -9842
CALML5 -10007
TMEM179B -10008
RNASET2 -10012
SPTAN1 -10082
CSTB -10147
PPIE -10203
NDUFC2 -10268
PFKL -10275
TBC1D10C -10502
FPR1 -10573
PSMD2 -10774
KRT1 -10820
S100A7 -10968


REACTOME_HATS_ACETYLATE_HISTONES

REACTOME_HATS_ACETYLATE_HISTONES
551
set REACTOME_HATS_ACETYLATE_HISTONES
setSize 129
pANOVA 3.67e-06
s.dist -0.236
p.adjustANOVA 0.00201



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC3 -11072.0
H3C3 -10752.0
H3C6 -10696.0
H2BC26 -10276.0
H2AC7 -10188.5
H2BC7 -10188.5
H2AC25 -10089.0
H2AC20 -10070.0
H2AC14 -9995.0
CLOCK -9787.0
TADA1 -9781.0
H3C4 -9701.0
SUPT20H -9673.0
PHF20 -9613.0
BRPF1 -9476.0
DR1 -9170.0
TRRAP -9080.0
H2AC18 -9031.5
H2AC19 -9031.5
EP400 -8902.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC3 -11072.0
H3C3 -10752.0
H3C6 -10696.0
H2BC26 -10276.0
H2AC7 -10188.5
H2BC7 -10188.5
H2AC25 -10089.0
H2AC20 -10070.0
H2AC14 -9995.0
CLOCK -9787.0
TADA1 -9781.0
H3C4 -9701.0
SUPT20H -9673.0
PHF20 -9613.0
BRPF1 -9476.0
DR1 -9170.0
TRRAP -9080.0
H2AC18 -9031.5
H2AC19 -9031.5
EP400 -8902.0
TAF6L -8732.0
ING5 -8414.0
HAT1 -8375.0
H3C1 -8260.0
NCOA1 -8254.0
H2BC14 -8236.0
ING3 -8081.0
H2AC21 -8042.0
H2AC8 -8007.0
MCRS1 -7889.0
KAT6A -7816.0
H4C1 -7768.0
H2BC8 -7687.0
RUVBL1 -7570.0
WDR5 -7515.0
H2BC21 -7485.0
H3C11 -7455.0
KANSL1 -7445.0
EP300 -7432.0
PAX3 -7192.0
TADA2A -7095.0
KAT2A -7092.0
TAF5L -6843.0
BRD1 -6812.0
ATXN7L3 -6350.0
ATXN7 -6164.0
H2AC1 -6019.0
MSL1 -5927.0
SGF29 -5801.0
KAT2B -5792.0
ACTL6A -5563.0
KAT5 -5557.0
H4C4 -5408.0
H2BC1 -5406.0
ELP4 -5318.0
H4C9 -5033.0
USP22 -4895.0
SUPT7L -4565.0
ELP6 -4402.0
ELP2 -4072.0
SUPT3H -3886.0
H4C3 -3847.0
BRD8 -3799.0
KANSL2 -3490.0
H2AC15 -3334.0
ZZZ3 -3077.0
NCOA2 -2942.0
JADE2 -2872.0
TAF12 -2722.0
MSL2 -2645.0
H4C6 -2615.0
KAT7 -2611.0
ENY2 -2379.0
MRGBP -2288.0
TAF9 -2271.0
H4C12 -2167.0
CREBBP -2076.0
YEATS2 -1826.0
H2BC12 -1743.0
KAT6B -1722.0
KANSL3 -1641.0
MEAF6 -1421.0
H4C16 -1250.0
H2AC4 -1132.0
H3C8 -1035.0
MORF4L1 -844.0
VPS72 -813.0
BRPF3 -745.0
H4C11 -494.0
H2BC11 -106.0
H2BC9 36.5
H3C7 36.5
ELP1 70.0
RUVBL2 158.0
H4C5 481.0
TADA3 523.0
H2BC10 1117.0
ING4 1305.0
SAP130 1467.0
EPC1 1524.0
H2AC12 1565.0
H2AC17 1568.0
TAF10 1944.0
H4C2 2031.0
ELP5 2331.0
H4C13 2526.0
H2BC17 2583.0
ELP3 2752.0
H2BC15 3952.0
H2BC5 4154.0
H3C2 4334.0
YEATS4 4563.0
JADE1 4583.0
DMAP1 5311.0
H2AC11 5446.0
H2AC13 5645.0
H2BC6 5880.0
MBIP 6137.0
TADA2B 6406.0
H2AC16 6664.0
H4C8 6856.0
ACTB 7403.0
ATF2 8104.0
H3C10 8230.0
KAT8 8643.0
H2BC13 8750.0
H2AC6 9114.0
H2BC4 9890.0
H3C12 10509.0


REACTOME_GPCR_LIGAND_BINDING

REACTOME_GPCR_LIGAND_BINDING
834
set REACTOME_GPCR_LIGAND_BINDING
setSize 444
pANOVA 1.13e-05
s.dist 0.122
p.adjustANOVA 0.00464



Top enriched genes

Top 20 genes
GeneID Gene Rank
TAS2R13 10616
ACKR4 10585
PTH2 10450
CXCR2 10434
GNG11 10395
CCL3 10370
SUCNR1 10345
MC5R 10281
HCAR1 10247
GPR4 10237
PPBP 10229
CCL5 10217
HTR1E 10215
CCL2 10159
DRD5 10142
C5AR1 10139
MLN 10135
GPHB5 10083
ADORA3 10082
PTCH2 10024

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TAS2R13 10616
ACKR4 10585
PTH2 10450
CXCR2 10434
GNG11 10395
CCL3 10370
SUCNR1 10345
MC5R 10281
HCAR1 10247
GPR4 10237
PPBP 10229
CCL5 10217
HTR1E 10215
CCL2 10159
DRD5 10142
C5AR1 10139
MLN 10135
GPHB5 10083
ADORA3 10082
PTCH2 10024
KEL 9990
CCL19 9979
KISS1R 9974
CCR3 9939
APLNR 9917
IAPP 9901
FSHB 9874
PLPPR3 9840
NMUR2 9785
ACKR1 9728
TACR3 9702
PDYN 9668
MTNR1B 9623
GALR2 9614
CXCL5 9518
GHRHR 9498
CXCL11 9458
NPB 9422
CXCL16 9408
HRH4 9388
MCHR1 9331
RXFP4 9311
CYSLTR2 9245
LPAR1 9244
NPY 9231
CXCL2 9177
NTS 9077
LPAR5 9053
UTS2R 9028
TAS2R41 9018
WNT1 8966
ADGRE1 8850
LHCGR 8838
C5AR2 8834
NMU 8819
PLPPR1 8796
FSHR 8764
TBXA2R 8693
TAS1R3 8578
CCR5 8539
TAC1 8510
P2RY13 8459
EDNRA 8456
LPAR3 8441
CCL23 8436
AVP 8433
S1PR5 8427
HCRTR2 8303
NPBWR1 8301
GNB5 8214
PTGER1 8154
NPY1R 8090
RLN2 8043
PTHLH 8025
NPY2R 7871
UCN3 7831
NPY5R 7802
GNG12 7733
AVPR1A 7684
GRM5 7649
ADCYAP1R1 7644
TAAR6 7553
HTR6 7496
CHRM2 7490
GALR1 7485
GHSR 7406
RAMP2 7347
CCR10 7336
HTR1A 7306
GNAS 7253
OXER1 7232
ADRA1D 7231
CCL1 7220
TAS2R10 7192
POMC 7181
FZD2 7150
CXCL3 7143
PLPPR5 7117
CMKLR1 7109
CALCR 7072
MC2R 7071
ACKR3 7039
P2RY6 7036
ADRB1 7026
PTGFR 6984
PLPPR2 6975
GNG8 6938
ADGRE3 6925
WNT2B 6907
PENK 6854
WNT10B 6840
GPBAR1 6814
WNT4 6810
FZD5 6795
GRM7 6682
LTB4R 6644
GIP 6560
CXCL6 6548
GRM2 6529
PTGER4 6466
FFAR3 6456
PTGDR2 6450
C5 6404
NPFF 6400
CRHR1 6335
CCL22 6316
ADM2 6299
SSTR1 6113
P2RY11 6104
FZD4 6057
UTS2B 6039
GPR132 5957
RLN3 5954
OXGR1 5951
TRH 5899
DHH 5764
TSHB 5734
PYY 5720
HTR2A 5694
WNT7A 5612
DRD1 5577
HTR7 5555
CALCA 5303
OPRL1 5265
IHH 5201
TAS2R14 5178
CX3CR1 5113
ECE2 5083
EDN3 5061
CCL11 5058
CXCL1 5052
WNT6 5007
P2RY12 4850
UCN 4814
GABBR2 4705
AGTR1 4704
TAS2R43 4687
GNG13 4682
PF4 4678
ADORA2B 4641
PRLHR 4628
RXFP1 4613
RXFP2 4606
DRD2 4592
CHRM1 4541
GRM1 4385
CCL17 4258
ADRB2 4192
ADRA1B 4134
WNT8A 4088
PROK2 4078
EDN2 4061
QRFP 4053
PNOC 4051
CCL28 4004
CXCR1 3976
MLNR 3963
RAMP1 3883
ADRA1A 3881
PROKR1 3879
ADORA1 3864
SSTR2 3862
ACKR2 3692
SCT 3647
RGR 3618
GHRH 3607
GPR39 3533
HRH1 3476
VIPR1 3429
GPR37 3394
WNT5A 3360
WNT8B 3238
ADRA2B 3235
NPW 3183
HRH3 3181
PTH1R 3074
CCRL2 3060
HTR1F 3050
TAS2R16 3037
PTGER3 3020
PTGER2 2987
CRH 2974
CCL4 2930
TAS2R20 2816
TAS2R50 2732
FFAR4 2687
CALCB 2671
FZD1 2582
WNT3A 2499
TAS2R30 2464
CXCL13 2440
CCKBR 2398
XCL2 2225
FZD9 2117
GCG 2002
LTB4R2 1954
TRHR 1877
ADCYAP1 1873
RXFP3 1870
NPS 1761
RHO 1712
SSTR5 1623
ADRA2A 1543
ADM 1391
ANXA1 1369
VIP 1345
SMO 1343
PTH2R 1270
S1PR3 1250
CASR 1240
CXCL12 1209
MC1R 1208
CCL25 1147
WNT9A 1016
NMUR1 1006
CALCRL 821
BDKRB1 648
FPR2 615
MTNR1A 566
CRHBP 562
FZD8 561
CNR2 463
CCR8 434
APP 410
HTR1B 387
HTR5A 263
GPR17 156
PTGDR 124
XCL1 -64
S1PR2 -89
NPFFR1 -125
P2RY1 -243
BDKRB2 -290
GIPR -396
TAS2R19 -405
TAS2R5 -462
GRP -477
WNT16 -516
EDNRB -527
FZD10 -542
OPN5 -599
TSHR -615
GRM8 -669
GNG2 -702
HRH2 -720
TAS1R2 -834
GNG5 -891
VIPR2 -1033
TAS2R31 -1061
F2RL1 -1064
HCAR2 -1107
GNB3 -1123
GNG4 -1138
GLP1R -1140
KNG1 -1179
TACR2 -1193
CHRM5 -1264
CCR4 -1326
LHB -1370
P2RY2 -1417
CHRM3 -1425
F2R -1436
LPAR6 -1488
PSAP -1493
CGA -1525
OPRK1 -1574
TAS2R3 -1636
TAS2R42 -1656
AVPR1B -1702
MC3R -1725
GPRC6A -1731
UTS2 -1830
GPR68 -1840
GRM4 -1851
EDN1 -1981
ECE1 -2038
TAS2R8 -2062
RAMP3 -2074
OXTR -2085
FPR3 -2117
F2RL2 -2141
CCR7 -2142
WNT11 -2200
CXCR4 -2279
C3AR1 -2289
CCL20 -2331
GPR55 -2363
UCN2 -2384
GNRH1 -2449
MCHR2 -2497
FFAR2 -2626
WNT10A -2671
PLPPR4 -2704
WNT7B -2755
GABBR1 -2768
GNGT2 -3018
GPR35 -3051
DRD4 -3120
GRM6 -3221
CCR2 -3268
XCR1 -3294
ADGRE2 -3319
WNT9B -3327
NTSR1 -3360
CCL13 -3429
GNG7 -3536
OPN1SW -3593
OPRM1 -3645
C3 -3747
PTAFR -3776
GAL -3792
WNT2 -3892
S1PR1 -3897
NPBWR2 -3985
TAS2R38 -4057
GNB2 -4115
SHH -4141
GNG10 -4182
GRM3 -4214
CRHR2 -4228
GALR3 -4243
NPFFR2 -4391
GNG3 -4555
TAS2R4 -4674
GPR31 -4686
NLN -4701
GPR37L1 -4720
OPRD1 -4993
HEBP1 -5020
HTR4 -5065
MC4R -5099
NPSR1 -5120
CCL16 -5150
GNB1 -5364
WNT3 -5382
ADRB3 -5421
NTSR2 -5439
CD55 -5455
PTCH1 -5478
ADGRE5 -5547
SCTR -5596
CHRM4 -5639
TAC3 -5652
HTR2B -5757
NMBR -5773
CCL27 -5921
QRFPR -5949
GPR65 -5953
INSL5 -6062
GNRHR -6081
F2 -6090
TACR1 -6109
TAAR1 -6126
GNRH2 -6211
AGT -6262
RRH -6292
CNR1 -6330
GHRL -6514
TAAR5 -6602
FZD3 -6701
P2RY14 -6879
NMB -7016
S1PR4 -7157
SST -7167
GPER1 -7252
NMS -7309
GNB4 -7354
GPR183 -7594
OPN3 -7634
PTH -7779
CXCL8 -7825
DRD3 -7830
GLP2R -8041
GNGT1 -8140
OXT -8167
INSL3 -8210
TAS2R7 -8275
CORT -8397
CXCL9 -8525
KISS1 -8563
F2RL3 -8601
TAS2R40 -8664
FZD6 -8718
SSTR3 -8941
HCRTR1 -9023
CCR1 -9135
FZD7 -9142
TAS1R1 -9213
OPN4 -9343
PROKR2 -9419
TAS2R9 -9571
PROK1 -9625
TAAR9 -9736
TAAR2 -9761
HTR1D -9801
TAS2R60 -9828
CCR9 -10013
TAS2R46 -10031
SAA1 -10073
CXCL10 -10155
FFAR1 -10163
PPY -10172
PMCH -10205
CCK -10232
ADRA2C -10233
TAS2R39 -10303
SSTR4 -10364
PRLH -10395
GPR18 -10449
ADORA2A -10485
LPAR2 -10537
HCRT -10543
CCL7 -10552
FPR1 -10573
CCR6 -10602
CXCR5 -10686
CX3CL1 -10719
CCKAR -10812
TAS2R1 -10843
CCL21 -11021
PTGIR -11030
CXCR6 -11069
TAAR8 -11075
GPHA2 -11256


REACTOME_SIGNALING_BY_GPCR

REACTOME_SIGNALING_BY_GPCR
593
set REACTOME_SIGNALING_BY_GPCR
setSize 673
pANOVA 0.000121
s.dist 0.0869
p.adjustANOVA 0.0399



Top enriched genes

Top 20 genes
GeneID Gene Rank
ARHGEF5 10634
TAS2R13 10616
ACKR4 10585
PTH2 10450
CXCR2 10434
GNAT2 10415
GNG11 10395
CCL3 10370
SUCNR1 10345
MC5R 10281
HCAR1 10247
GPR4 10237
PPBP 10229
CCL5 10217
HTR1E 10215
CCL2 10159
DRD5 10142
C5AR1 10139
MLN 10135
GPHB5 10083

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ARHGEF5 10634
TAS2R13 10616
ACKR4 10585
PTH2 10450
CXCR2 10434
GNAT2 10415
GNG11 10395
CCL3 10370
SUCNR1 10345
MC5R 10281
HCAR1 10247
GPR4 10237
PPBP 10229
CCL5 10217
HTR1E 10215
CCL2 10159
DRD5 10142
C5AR1 10139
MLN 10135
GPHB5 10083
ADORA3 10082
PTCH2 10024
KEL 9990
CCL19 9979
KISS1R 9974
CCR3 9939
APLNR 9917
MMP3 9909
IAPP 9901
RGS21 9899
FSHB 9874
PLPPR3 9840
NMUR2 9785
ACKR1 9728
TACR3 9702
PDYN 9668
MTNR1B 9623
GALR2 9614
FGD4 9592
CXCL5 9518
GHRHR 9498
GRK2 9489
CXCL11 9458
NPB 9422
CXCL16 9408
ARHGEF39 9400
HRH4 9388
PPP1R1B 9359
MCHR1 9331
NBEA 9323
RXFP4 9311
CYSLTR2 9245
LPAR1 9244
NPY 9231
CXCL2 9177
NTS 9077
LPAR5 9053
PRKCD 9030
UTS2R 9028
TAS2R41 9018
WNT1 8966
ADGRE1 8850
LHCGR 8838
C5AR2 8834
NMU 8819
PDE3B 8806
PLPPR1 8796
FSHR 8764
PIK3R6 8744
TBXA2R 8693
RGS16 8645
TAS1R3 8578
GNAI2 8546
CCR5 8539
TAC1 8510
P2RY13 8459
EDNRA 8456
LPAR3 8441
CCL23 8436
AVP 8433
S1PR5 8427
PRKAR2A 8317
HCRTR2 8303
NPBWR1 8301
GNB5 8214
DGKG 8171
PTGER1 8154
NPY1R 8090
PLCB1 8087
EGFR 8078
RLN2 8043
PTHLH 8025
NPY2R 7871
NRAS 7853
UCN3 7831
NPY5R 7802
GNG12 7733
SHC1 7700
AVPR1A 7684
GRM5 7649
ADCYAP1R1 7644
TAAR6 7553
ADCY8 7533
CAMK2G 7517
ARHGEF26 7515
HTR6 7496
CHRM2 7490
GALR1 7485
GHSR 7406
RAMP2 7347
CCR10 7336
RGS18 7325
HTR1A 7306
GNAS 7253
RPS6KA1 7236
OXER1 7232
ADRA1D 7231
CCL1 7220
TAS2R10 7192
POMC 7181
FZD2 7150
CXCL3 7143
PLPPR5 7117
CMKLR1 7109
CALCR 7072
MC2R 7071
ACKR3 7039
P2RY6 7036
ADRB1 7026
PTGFR 6984
PLPPR2 6975
GNG8 6938
ADGRE3 6925
WNT2B 6907
PENK 6854
PRKCG 6850
WNT10B 6840
GPBAR1 6814
WNT4 6810
FZD5 6795
NET1 6793
PRKACB 6694
GRM7 6682
LTB4R 6644
GIP 6560
CXCL6 6548
MGLL 6530
GRM2 6529
GPR150 6499
CAMK2D 6489
PTGER4 6466
FFAR3 6456
PTGDR2 6450
C5 6404
GNAQ 6401
NPFF 6400
PPP2CA 6363
CRHR1 6335
CCL22 6316
ADM2 6299
PLCB4 6213
CDC42 6209
GPR84 6200
PDE2A 6140
PDE10A 6117
SSTR1 6113
P2RY11 6104
FZD4 6057
UTS2B 6039
GPR132 5957
RLN3 5954
OXGR1 5951
TRH 5899
SOS1 5823
GAST 5811
ARHGEF19 5786
RGS11 5785
DHH 5764
TSHB 5734
PYY 5720
PDE3A 5699
ADCY4 5698
HTR2A 5694
TIAM1 5679
WNT7A 5612
DRD1 5577
HTR7 5555
DAGLA 5453
ARRB1 5403
CALCA 5303
PDE4D 5290
OPRL1 5265
IHH 5201
TAS2R14 5178
CX3CR1 5113
KALRN 5111
ECE2 5083
EDN3 5061
CCL11 5058
CXCL1 5052
WNT6 5007
PIK3R1 4998
ARHGEF3 4961
P2RY12 4850
UCN 4814
GPSM3 4801
ITGB1 4790
GRB2 4749
GABBR2 4705
AGTR1 4704
TAS2R43 4687
GNG13 4682
PF4 4678
PDE1C 4676
ADORA2B 4641
PRLHR 4628
RXFP1 4613
RXFP2 4606
DRD2 4592
CHRM1 4541
VAV1 4399
GRM1 4385
RGS6 4348
CCL17 4258
ADRB2 4192
ADRA1B 4134
WNT8A 4088
PROK2 4078
AHCYL1 4064
EDN2 4061
QRFP 4053
PNOC 4051
CCL28 4004
DGKB 3997
CXCR1 3976
MLNR 3963
RAMP1 3883
ADRA1A 3881
PROKR1 3879
ADORA1 3864
SSTR2 3862
ACKR2 3692
SCT 3647
RGR 3618
GHRH 3607
GPR39 3533
HRH1 3476
PRKAR1A 3464
VIPR1 3429
GPR37 3394
GNAI1 3381
PAK1 3361
WNT5A 3360
PIK3CA 3346
PRKAR2B 3261
WNT8B 3238
ADRA2B 3235
RASGRF2 3225
NPW 3183
HRH3 3181
ARHGEF25 3170
ITGA5 3123
PRKCE 3086
PTH1R 3074
CCRL2 3060
HTR1F 3050
TAS2R16 3037
PTGER3 3020
DGKI 3010
PTGER2 2987
PPP2R1B 2977
CRH 2974
CCL4 2930
TAS2R20 2816
TAS2R50 2732
ABHD6 2716
PPP3CA 2706
RGS19 2704
FFAR4 2687
CALCB 2671
PIK3R5 2645
SRC 2638
ITPR2 2592
FZD1 2582
OBSCN 2555
WNT3A 2499
TAS2R30 2464
CXCL13 2440
CCKBR 2398
TRIO 2327
GRK5 2304
XCL2 2225
HBEGF 2127
FZD9 2117
PPP2R5D 2036
GCG 2002
LTB4R2 1954
ROCK1 1951
TRHR 1877
RHOC 1875
ADCYAP1 1873
RXFP3 1870
RGS13 1860
PDE1A 1820
ADCY1 1793
NPS 1761
RHO 1712
ADCY6 1641
PLA2G4A 1634
SSTR5 1623
PDE4B 1581
ADRA2A 1543
PRKCA 1517
RGS22 1505
ADCY2 1409
ADM 1391
ANXA1 1369
VIP 1345
SMO 1343
PDE1B 1342
MAPK1 1304
PTH2R 1270
S1PR3 1250
CASR 1240
CXCL12 1209
MC1R 1208
CCL25 1147
RPS6KA2 1136
ADCY5 1097
PIK3R2 1089
PREX1 1065
RGS9 1033
WNT9A 1016
NMUR1 1006
PPP1CA 1000
RGS10 892
CALCRL 821
GRK3 784
GNA15 653
BDKRB1 648
FPR2 615
RGS7 612
ARHGEF11 596
PDE8A 571
MTNR1A 566
CRHBP 562
FZD8 561
TRPC7 553
PPP2R1A 545
RASGRP2 487
CNR2 463
VAV3 447
CCR8 434
APP 410
HTR1B 387
GNA12 286
HTR5A 263
NGEF 186
GPR17 156
PTGDR 124
FN1 29
XCL1 -64
ARHGEF12 -83
S1PR2 -89
NPFFR1 -125
DGKZ -152
P2RY1 -243
BDKRB2 -290
PDE4C -298
GIPR -396
TAS2R19 -405
GNA11 -413
PPP3CC -429
TAS2R5 -462
ARHGEF38 -470
GRP -477
WNT16 -516
EDNRB -527
TRPC6 -534
FZD10 -542
GNA14 -562
OPN5 -599
TSHR -615
ADCY9 -632
GRM8 -669
GNG2 -702
VAV2 -718
HRH2 -720
TAS1R2 -834
GPR176 -840
GNG5 -891
GPR27 -942
PDE4A -964
VIPR2 -1033
TAS2R31 -1061
F2RL1 -1064
HCAR2 -1107
GNB3 -1123
GNG4 -1138
GLP1R -1140
KNG1 -1179
TACR2 -1193
ARHGEF10L -1214
ABR -1223
ARHGEF17 -1225
CHRM5 -1264
AKT3 -1295
CCR4 -1326
GNAT3 -1350
LHB -1370
RGS8 -1374
P2RY2 -1417
CHRM3 -1425
F2R -1436
DGKH -1451
LPAR6 -1488
PSAP -1493
CGA -1525
CAMK2B -1528
GPSM1 -1568
OPRK1 -1574
TAS2R3 -1636
TAS2R42 -1656
ITPR1 -1665
AVPR1B -1702
PRKACG -1720
MC3R -1725
GPRC6A -1731
MCF2L -1780
ARHGEF4 -1783
RHOA -1807
UTS2 -1830
GPR68 -1840
GRM4 -1851
AKAP13 -1872
KPNA2 -1894
GNAI3 -1954
EDN1 -1981
ARHGEF33 -2020
ECE1 -2038
TAS2R8 -2062
RAMP3 -2074
OXTR -2085
PRKCQ -2103
FPR3 -2117
F2RL2 -2141
CCR7 -2142
WNT11 -2200
ARHGEF10 -2229
CXCR4 -2279
C3AR1 -2289
CCL20 -2331
GPR55 -2363
UCN2 -2384
GNRH1 -2449
PIK3R3 -2476
PDE11A -2484
MCHR2 -2497
FFAR2 -2626
WNT10A -2671
PLPPR4 -2704
WNT7B -2755
GABBR1 -2768
RGS2 -2877
RGS17 -2900
GNGT2 -3018
GPR35 -3051
DRD4 -3120
PIK3CG -3150
GRM6 -3221
PCP2 -3252
CCR2 -3268
XCR1 -3294
PDE8B -3296
PRKAR1B -3310
ADGRE2 -3319
WNT9B -3327
NTSR1 -3360
ITPR3 -3377
CAMK4 -3380
CCL13 -3429
PLEKHG2 -3470
ARHGEF18 -3505
GNG7 -3536
TRPC3 -3551
OPN1SW -3593
ARHGEF2 -3612
OPRM1 -3645
ROCK2 -3673
GPR83 -3691
RGS14 -3702
ARHGEF40 -3735
C3 -3747
PDE7A -3770
PTAFR -3776
GAL -3792
ARRB2 -3809
CAMK2A -3859
WNT2 -3892
S1PR1 -3897
NPBWR2 -3985
MAPK7 -3992
PPP3R1 -4013
TAS2R38 -4057
PPP3CB -4085
GNB2 -4115
RGS20 -4118
SHH -4141
DAGLB -4156
GNG10 -4182
GRM3 -4214
CRHR2 -4228
PRKACA -4231
ITSN1 -4234
RGS4 -4240
GALR3 -4243
GNAL -4314
NPFFR2 -4391
RGS1 -4413
KRAS -4450
RGS5 -4456
GNG3 -4555
PLEKHG5 -4561
PRKCB -4672
TAS2R4 -4674
GPR31 -4686
NLN -4701
GPR37L1 -4720
GNAZ -4767
OPRD1 -4993
HEBP1 -5020
PLCB3 -5028
HTR4 -5065
DGKD -5090
MC4R -5099
NPSR1 -5120
ARHGEF37 -5133
PLXNB1 -5139
CCL16 -5150
CAMKK1 -5206
FGD2 -5279
GNB1 -5364
CREB1 -5377
WNT3 -5382
ADRB3 -5421
NTSR2 -5439
CD55 -5455
PTCH1 -5478
RHOB -5521
ADGRE5 -5547
SCTR -5596
CHRM4 -5639
TAC3 -5652
GNA13 -5712
HTR2B -5757
NMBR -5773
ARHGEF7 -5798
TIAM2 -5828
CCL27 -5921
QRFPR -5949
GPR65 -5953
INSL5 -6062
GNRHR -6081
F2 -6090
TACR1 -6109
TAAR1 -6126
GRK6 -6130
CDK5 -6162
GNRH2 -6211
AGT -6262
RRH -6292
CNR1 -6330
GPSM2 -6467
PPP2CB -6478
GNAT1 -6498
GHRL -6514
MAPK3 -6553
PDE7B -6567
RGS12 -6589
ECT2 -6597
TAAR5 -6602
FZD3 -6701
CAMKK2 -6714
PLCB2 -6769
P2RY14 -6879
NMB -7016
ABHD12 -7156
S1PR4 -7157
SST -7167
GPER1 -7252
NMS -7309
GNB4 -7354
RGS3 -7379
SOS2 -7482
GPR183 -7594
OPN3 -7634
AKT1 -7654
DGKE -7664
PTH -7779
RGSL1 -7815
CXCL8 -7825
DRD3 -7830
DGKA -8005
HRAS -8010
DGKQ -8037
GLP2R -8041
GNGT1 -8140
PRKCH -8164
OXT -8167
ADCY3 -8198
INSL3 -8210
TAS2R7 -8275
ARHGEF15 -8312
CORT -8397
RASGRP1 -8404
CXCL9 -8525
KISS1 -8563
F2RL3 -8601
TAS2R40 -8664
FZD6 -8718
ARHGEF1 -8754
PDPK1 -8775
GPR25 -8900
CALM1 -8933
SSTR3 -8941
FGD3 -8971
HCRTR1 -9023
CCR1 -9135
FZD7 -9142
TAS1R1 -9213
ADCY7 -9295
OPN4 -9343
PROKR2 -9419
TAS2R9 -9571
PROK1 -9625
GPR20 -9719
TAAR9 -9736
TAAR2 -9761
HTR1D -9801
TAS2R60 -9828
AKT2 -9950
CCR9 -10013
TAS2R46 -10031
SAA1 -10073
CXCL10 -10155
FFAR1 -10163
PPY -10172
PMCH -10205
CCK -10232
ADRA2C -10233
TAS2R39 -10303
SSTR4 -10364
PRLH -10395
GPR18 -10449
ARHGEF16 -10454
ADORA2A -10485
GPR32 -10507
LPAR2 -10537
HCRT -10543
CCL7 -10552
FPR1 -10573
CCR6 -10602
CXCR5 -10686
CX3CL1 -10719
GPR15 -10727
CCKAR -10812
TAS2R1 -10843
GPR45 -10904
CCL21 -11021
PTGIR -11030
CXCR6 -11069
TAAR8 -11075
GPHA2 -11256


REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS
594
set REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS
setSize 312
pANOVA 0.000158
s.dist 0.124
p.adjustANOVA 0.0433



Top enriched genes

Top 20 genes
GeneID Gene Rank
ACKR4 10585
CXCR2 10434
CCL3 10370
SUCNR1 10345
MC5R 10281
HCAR1 10247
GPR4 10237
PPBP 10229
CCL5 10217
HTR1E 10215
CCL2 10159
DRD5 10142
C5AR1 10139
MLN 10135
GPHB5 10083
ADORA3 10082
KEL 9990
CCL19 9979
KISS1R 9974
CCR3 9939

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ACKR4 10585
CXCR2 10434
CCL3 10370
SUCNR1 10345
MC5R 10281
HCAR1 10247
GPR4 10237
PPBP 10229
CCL5 10217
HTR1E 10215
CCL2 10159
DRD5 10142
C5AR1 10139
MLN 10135
GPHB5 10083
ADORA3 10082
KEL 9990
CCL19 9979
KISS1R 9974
CCR3 9939
APLNR 9917
FSHB 9874
PLPPR3 9840
NMUR2 9785
ACKR1 9728
TACR3 9702
PDYN 9668
MTNR1B 9623
GALR2 9614
CXCL5 9518
CXCL11 9458
NPB 9422
CXCL16 9408
HRH4 9388
MCHR1 9331
RXFP4 9311
CYSLTR2 9245
LPAR1 9244
NPY 9231
CXCL2 9177
NTS 9077
LPAR5 9053
UTS2R 9028
LHCGR 8838
C5AR2 8834
NMU 8819
PLPPR1 8796
FSHR 8764
TBXA2R 8693
CCR5 8539
TAC1 8510
P2RY13 8459
EDNRA 8456
LPAR3 8441
CCL23 8436
AVP 8433
S1PR5 8427
HCRTR2 8303
NPBWR1 8301
PTGER1 8154
NPY1R 8090
RLN2 8043
NPY2R 7871
NPY5R 7802
AVPR1A 7684
TAAR6 7553
HTR6 7496
CHRM2 7490
GALR1 7485
GHSR 7406
CCR10 7336
HTR1A 7306
OXER1 7232
ADRA1D 7231
CCL1 7220
POMC 7181
CXCL3 7143
PLPPR5 7117
CMKLR1 7109
MC2R 7071
ACKR3 7039
P2RY6 7036
ADRB1 7026
PTGFR 6984
PLPPR2 6975
PENK 6854
GPBAR1 6814
LTB4R 6644
CXCL6 6548
PTGER4 6466
FFAR3 6456
PTGDR2 6450
C5 6404
NPFF 6400
CCL22 6316
SSTR1 6113
P2RY11 6104
UTS2B 6039
GPR132 5957
RLN3 5954
OXGR1 5951
TRH 5899
TSHB 5734
PYY 5720
HTR2A 5694
DRD1 5577
HTR7 5555
OPRL1 5265
CX3CR1 5113
ECE2 5083
EDN3 5061
CCL11 5058
CXCL1 5052
P2RY12 4850
AGTR1 4704
PF4 4678
ADORA2B 4641
PRLHR 4628
RXFP1 4613
RXFP2 4606
DRD2 4592
CHRM1 4541
CCL17 4258
ADRB2 4192
ADRA1B 4134
PROK2 4078
EDN2 4061
QRFP 4053
PNOC 4051
CCL28 4004
CXCR1 3976
MLNR 3963
ADRA1A 3881
PROKR1 3879
ADORA1 3864
SSTR2 3862
ACKR2 3692
RGR 3618
GPR39 3533
HRH1 3476
GPR37 3394
ADRA2B 3235
NPW 3183
HRH3 3181
CCRL2 3060
HTR1F 3050
PTGER3 3020
PTGER2 2987
CCL4 2930
FFAR4 2687
CXCL13 2440
CCKBR 2398
XCL2 2225
LTB4R2 1954
TRHR 1877
RXFP3 1870
NPS 1761
RHO 1712
SSTR5 1623
ADRA2A 1543
ANXA1 1369
S1PR3 1250
CXCL12 1209
MC1R 1208
CCL25 1147
NMUR1 1006
BDKRB1 648
FPR2 615
MTNR1A 566
CNR2 463
CCR8 434
APP 410
HTR1B 387
HTR5A 263
GPR17 156
PTGDR 124
XCL1 -64
S1PR2 -89
NPFFR1 -125
P2RY1 -243
BDKRB2 -290
GRP -477
EDNRB -527
OPN5 -599
TSHR -615
HRH2 -720
F2RL1 -1064
HCAR2 -1107
KNG1 -1179
TACR2 -1193
CHRM5 -1264
CCR4 -1326
LHB -1370
P2RY2 -1417
CHRM3 -1425
F2R -1436
LPAR6 -1488
PSAP -1493
CGA -1525
OPRK1 -1574
AVPR1B -1702
MC3R -1725
UTS2 -1830
GPR68 -1840
EDN1 -1981
ECE1 -2038
OXTR -2085
FPR3 -2117
F2RL2 -2141
CCR7 -2142
CXCR4 -2279
C3AR1 -2289
CCL20 -2331
GPR55 -2363
GNRH1 -2449
MCHR2 -2497
FFAR2 -2626
PLPPR4 -2704
GPR35 -3051
DRD4 -3120
CCR2 -3268
XCR1 -3294
NTSR1 -3360
CCL13 -3429
OPN1SW -3593
OPRM1 -3645
C3 -3747
PTAFR -3776
GAL -3792
S1PR1 -3897
NPBWR2 -3985
GALR3 -4243
NPFFR2 -4391
GPR31 -4686
NLN -4701
GPR37L1 -4720
OPRD1 -4993
HEBP1 -5020
HTR4 -5065
MC4R -5099
NPSR1 -5120
CCL16 -5150
ADRB3 -5421
NTSR2 -5439
CHRM4 -5639
TAC3 -5652
HTR2B -5757
NMBR -5773
CCL27 -5921
QRFPR -5949
GPR65 -5953
INSL5 -6062
GNRHR -6081
F2 -6090
TACR1 -6109
TAAR1 -6126
GNRH2 -6211
AGT -6262
RRH -6292
CNR1 -6330
GHRL -6514
TAAR5 -6602
P2RY14 -6879
NMB -7016
S1PR4 -7157
SST -7167
GPER1 -7252
NMS -7309
GPR183 -7594
OPN3 -7634
CXCL8 -7825
DRD3 -7830
OXT -8167
INSL3 -8210
CORT -8397
CXCL9 -8525
KISS1 -8563
F2RL3 -8601
SSTR3 -8941
HCRTR1 -9023
CCR1 -9135
OPN4 -9343
PROKR2 -9419
PROK1 -9625
TAAR9 -9736
TAAR2 -9761
HTR1D -9801
CCR9 -10013
SAA1 -10073
CXCL10 -10155
FFAR1 -10163
PPY -10172
PMCH -10205
CCK -10232
ADRA2C -10233
SSTR4 -10364
PRLH -10395
GPR18 -10449
ADORA2A -10485
LPAR2 -10537
HCRT -10543
CCL7 -10552
FPR1 -10573
CCR6 -10602
CXCR5 -10686
CX3CL1 -10719
CCKAR -10812
CCL21 -11021
PTGIR -11030
CXCR6 -11069
TAAR8 -11075
GPHA2 -11256


REACTOME_INNATE_IMMUNE_SYSTEM

REACTOME_INNATE_IMMUNE_SYSTEM
227
set REACTOME_INNATE_IMMUNE_SYSTEM
setSize 1002
pANOVA 0.000408
s.dist 0.066
p.adjustANOVA 0.0774



Top enriched genes

Top 20 genes
GeneID Gene Rank
FOLR3 10725
RNASE3 10721
S100A8 10716
AZU1 10713
MPO 10712
IFNA7 10694
FCGR3B 10667
S100A9 10644
RNASE2 10626
CTSG 10578
PGLYRP1 10543
CLEC4D 10522
LRG1 10514
LILRB2 10513
CD209 10504
SFTPA1 10501
SLPI 10489
HTN1 10482
CEACAM6 10480
OLR1 10444

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FOLR3 10725.0
RNASE3 10721.0
S100A8 10716.0
AZU1 10713.0
MPO 10712.0
IFNA7 10694.0
FCGR3B 10667.0
S100A9 10644.0
RNASE2 10626.0
CTSG 10578.0
PGLYRP1 10543.0
CLEC4D 10522.0
LRG1 10514.0
LILRB2 10513.0
CD209 10504.0
SFTPA1 10501.0
SLPI 10489.0
HTN1 10482.0
CEACAM6 10480.0
OLR1 10444.0
CD300E 10441.0
FCER1G 10439.0
CXCR2 10434.0
SERPINA1 10426.0
IFNA8 10425.0
CD180 10414.0
CD300LB 10413.0
FCN2 10396.0
TYROBP 10391.0
PRTN3 10385.0
RETN 10341.0
CD93 10340.0
CD177 10334.0
HSPA6 10330.0
DCD 10296.0
PPBP 10229.0
CTSK 10220.0
HP 10213.0
TLR4 10185.0
C5AR1 10139.0
LCN2 10128.0
CDA 10120.0
CFHR2 10110.0
DEFA6 10080.0
MUC12 10077.0
CD68 10075.0
MBL2 10065.0
FGA 10032.0
PYCARD 10029.0
PLAU 10020.0
DEFA4 10012.0
DEFB110 10007.0
LYZ 9989.0
VAT1 9975.0
ADGRG3 9960.0
CLEC10A 9944.0
DEFA5 9942.0
SIRPB1 9940.0
PSTPIP1 9914.0
IL1B 9883.0
ELANE 9879.0
CEACAM3 9834.0
IFNA2 9826.0
AIM2 9818.0
FGR 9815.0
PTPRJ 9807.0
P2RX7 9776.0
DOK3 9765.0
GSN 9762.0
MANBA 9699.0
LEAP2 9689.0
CTSL 9667.0
MNDA 9653.0
CLEC7A 9626.0
GMFG 9600.0
FCGR3A 9556.0
FABP5 9533.0
DEFB114 9521.0
LILRB3 9444.0
RAB3D 9430.0
CTSV 9420.0
MS4A3 9409.0
FCER1A 9382.0
SERPINB1 9378.0
CLEC4A 9371.0
MEFV 9346.0
GHDC 9327.0
IFNA6 9289.0
FCN1 9254.0
GNS 9239.0
PLD1 9219.0
TARM1 9187.0
NLRC4 9169.0
OSCAR 9164.0
LPO 9156.0
C8B 9150.0
GDI2 9120.0
CD59 9095.0
TNFRSF1B 9070.0
SLC11A1 9061.0
RNF135 9048.0
PRKCD 9030.0
AGPAT2 8977.0
C1QC 8975.0
VNN1 8952.0
ARMC8 8951.0
TRAF6 8941.0
CD33 8896.0
GLIPR1 8890.0
DEFB135 8846.0
C5AR2 8834.0
EPX 8827.0
GSTP1 8743.0
DEFB119 8742.0
DEFB104A 8737.5
DEFB104B 8737.5
PSMA6 8714.0
SERPINA3 8709.0
SVIP 8627.0
CUL1 8619.0
PSMB7 8601.0
TLR6 8600.0
CTSZ 8592.0
CTSD 8552.0
SERPINB12 8496.0
CFD 8484.0
ATP6V1B1 8476.0
STING1 8449.0
CASP1 8437.0
STBD1 8431.0
SLC27A2 8380.0
RAC2 8377.0
NFKBIA 8359.0
RNASE6 8328.0
PLD4 8325.0
PRDX6 8288.0
AMPD3 8287.0
ATP6V0E2 8260.0
NLRP3 8245.0
PSMB3 8195.0
ATF2 8104.0
UBE2N 8089.0
PSMA1 8054.0
HLA-B 8040.0
MCEMP1 8016.0
FLG2 7995.0
SIRPA 7986.0
DOCK2 7955.0
ATP6V1B2 7916.0
RAB37 7881.0
DEFB133 7877.0
VAMP8 7854.0
NRAS 7853.0
FCAR 7827.0
HSPA1B 7790.0
SFTPD 7710.0
SHC1 7700.0
MAPKAPK3 7673.0
CAP1 7661.0
ACTR2 7628.0
UBA52 7581.0
CKAP4 7580.0
PGM2 7555.0
S100A11 7549.0
DEFB124 7531.0
ADAM8 7522.0
RHOG 7516.0
S100A12 7414.0
SLCO4C1 7410.0
ACTB 7403.0
HK3 7384.0
SERPINB10 7381.0
SIGLEC14 7361.0
PYGL 7358.0
APOB 7310.0
DSN1 7300.0
TLR9 7297.0
NAPRT 7277.0
RPS6KA1 7236.0
S100P 7227.0
NKIRAS2 7148.0
TXNDC5 7136.0
TREM1 7133.0
CLEC5A 7132.0
APRT 7122.0
CPNE3 7057.0
PI3 7040.0
HERC5 6993.0
DUSP3 6950.0
ADGRE3 6925.0
PADI2 6893.0
HEXB 6891.0
C7 6860.0
PSMA2 6848.0
C1orf35 6781.0
RAB27A 6776.0
PSMC2 6774.0
AHSG 6766.0
BCL2 6758.0
UBE2V1 6756.0
RNASE8 6747.0
CASP4 6700.0
PRKACB 6694.0
ATP6V1C1 6688.0
CTSH 6597.0
POLR3D 6595.0
ISG15 6588.0
FBXW11 6554.0
DGAT1 6540.0
CTSA 6522.0
MYH2 6452.0
CFHR5 6426.0
C5 6404.0
PSMB8 6380.0
PPP2CA 6363.0
NPC2 6319.0
CCL22 6316.0
P2RX1 6296.0
TNFAIP3 6295.0
ABI2 6293.0
RIGI 6257.0
CDC42 6209.0
DUSP6 6207.0
GPR84 6200.0
PRSS3 6196.0
DEFB1 6185.0
IFNA14 6111.0
CGAS 6105.0
LPCAT1 6099.0
ACP3 6085.0
NHLRC3 6075.0
DUSP7 6026.0
GAB2 5996.0
BIRC3 5967.0
KCMF1 5902.0
NKIRAS1 5876.0
SOS1 5823.0
WIPF2 5815.0
C6orf120 5791.0
MASP2 5743.0
TEC 5711.0
CTSB 5709.0
SDCBP 5661.0
POLR3GL 5657.0
TMC6 5653.0
MEF2C 5633.0
VRK3 5624.0
IFNA16 5556.0
CLU 5535.0
CEP290 5498.0
CREG1 5490.0
DNM3 5441.0
SARM1 5434.0
LTA4H 5394.0
ATP6V1G1 5363.0
CD300A 5357.0
IFI16 5326.0
IST1 5285.0
COPB1 5241.0
LILRA3 5202.0
CLEC12A 5182.0
SEM1 5155.0
ATP6V0A1 5145.0
PLPP4 5130.0
PANX1 5121.0
BTRC 5091.0
UBE2D3 5089.0
RAB5B 5075.0
CLEC6A 5068.0
CD46 5067.0
CXCL1 5052.0
DEFB127 5037.0
PIK3R1 4998.0
MAPK10 4995.0
SLC15A4 4985.0
AGER 4952.0
ICAM3 4937.0
CD14 4930.0
UNC93B1 4929.0
CHRNB4 4883.0
BCL10 4841.0
LYN 4807.0
B2M 4789.0
EEF1A1 4767.0
GRB2 4749.0
PSEN1 4717.0
GRN 4711.0
NOS1 4677.0
DNAJC3 4670.0
CHI3L1 4664.0
PSMB4 4596.0
DIAPH1 4574.0
SIKE1 4568.0
MYO5A 4565.0
DEGS1 4515.0
PNP 4503.0
ALDOC 4500.0
MUC20 4495.0
C1QA 4482.0
RAB31 4466.0
SIGLEC15 4458.0
ATG12 4429.0
DSC1 4411.0
VAV1 4399.0
CD58 4398.0
LGALS3 4394.0
CRISPLD2 4380.0
CPN1 4354.0
SLC2A5 4344.0
TBK1 4333.0
NOS3 4316.0
CR1 4271.0
CCL17 4258.0
POLR1C 4240.0
ACTR10 4211.0
PSMD14 4205.0
ELMO2 4196.0
DNAJC5 4193.0
PSMC1 4146.0
SRP14 4144.0
NLRP1 4110.0
PKM 4085.0
MAVS 4082.0
AHCYL1 4064.0
MAP3K14 4038.0
VCL 4001.0
CXCR1 3976.0
BIN2 3961.0
ATP6V0D1 3954.0
TXNIP 3939.0
RNF125 3930.0
NCF2 3924.0
IRAG2 3898.0
TRAPPC1 3892.0
HVCN1 3890.0
ALDH3B1 3886.0
ERP44 3874.0
COTL1 3805.0
PSMA7 3774.0
MAPK11 3751.0
PLAUR 3697.0
TANK 3695.0
PSMD4 3652.0
C9 3625.0
SLC2A3 3614.0
CASP10 3527.0
TRPM2 3505.0
CTSC 3493.0
PRG2 3478.0
GM2A 3436.0
PSMC5 3435.0
HSP90AB1 3410.0
FADD 3401.0
MYD88 3400.0
B4GALT1 3375.0
PAK1 3361.0
PLAC8 3358.0
PIK3CA 3346.0
ATP6V1G2 3272.0
DHX9 3257.0
GYG1 3255.0
IDH1 3185.0
ATP6V0D2 3174.0
NME2 3121.0
POLR1D 3112.0
LRRFIP1 3106.0
PRKCE 3086.0
MAPK12 3081.0
RAB5C 3065.0
IRAK4 3028.0
SNAP23 3006.0
CYSTM1 2997.0
NFATC2 2983.0
PPP2R1B 2977.0
STAT6 2962.0
DDOST 2960.0
CTSS 2926.0
HPSE 2900.0
TOM1 2879.0
FOS 2852.0
TNFAIP6 2840.0
TOMM70 2837.0
C8G 2828.0
ALOX5 2826.0
PSMD3 2823.0
IMPDH1 2807.0
IRAK2 2804.0
CD53 2786.0
MAPK8 2729.0
ACTG1 2718.0
PPP3CA 2706.0
SRC 2638.0
TMEM30A 2611.0
CASP9 2594.0
ITPR2 2592.0
ARG1 2580.0
ENPP4 2544.0
BPIFB1 2529.0
DBNL 2524.0
MAPKAPK2 2481.0
WASF1 2461.0
NBEAL2 2437.0
PSMB5 2383.0
DEFB121 2341.0
UBA7 2283.0
ELMO1 2244.0
RAP2B 2209.0
LY96 2198.0
NCR2 2165.0
IRAK3 2149.0
BST1 2133.0
ATP6V1D 2105.0
MGAM 2092.0
PPP2R5D 2036.0
IFNA1 2022.0
KPNB1 1994.0
CD63 1972.0
ACTR3 1968.0
CCT8 1966.0
ROCK1 1951.0
KLRK1 1942.0
PIK3CB 1937.0
PLEKHO2 1936.0
UBE2K 1917.0
MEF2A 1904.0
NIT2 1889.0
IFNA13 1845.0
DERA 1835.0
PTPN11 1816.0
PRCP 1792.0
MYO10 1672.0
SELL 1669.0
WIPF1 1651.0
PSME4 1640.0
TAX1BP1 1632.0
FTH1 1606.0
PSMD5 1604.0
ADAM10 1586.0
ABI1 1575.0
FGB 1536.0
MAP2K6 1531.0
RIPK3 1497.0
PKP1 1480.0
ANPEP 1479.0
PA2G4 1445.0
PSMB9 1422.0
SCAMP1 1346.0
RAP1A 1344.0
MAPK1 1304.0
MME 1300.0
PIN1 1294.0
TUBB 1258.0
IFIH1 1244.0
CR2 1223.0
SEMG1 1216.0
ARSA 1202.0
ARPC4 1195.0
RPS6KA2 1136.0
POLR3A 1111.0
PIK3R2 1089.0
C1S 1071.0
ILF2 1069.0
FTL 1068.0
CAB39 1047.0
SYK 1005.0
C4BPB 994.0
TUBB4B 988.0
PIGR 975.0
CFH 973.0
LGMN 972.0
CHGA 943.0
ITGAL 937.0
WIPF3 931.0
APAF1 883.0
TREM2 879.0
C1R 877.0
PPIA 857.0
ORM2 852.0
PGLYRP4 850.0
FCN3 840.0
ALDOA 834.0
LAMTOR1 825.0
RAB24 797.0
PRKDC 786.0
STK10 785.0
DNM1 754.0
GOLGA7 749.0
MAPK13 743.0
PELI3 707.0
IQGAP2 694.0
ZBP1 688.0
PLD3 672.0
POLR3H 666.0
MMP8 657.0
MYO9B 638.0
FPR2 615.0
MUC15 593.0
CRCP 579.0
PPP2R1A 545.0
PRKCSH 492.0
RASGRP2 487.0
EPPIN-WFDC6 472.0
POLR2F 466.0
VAV3 447.0
STOM 433.0
RPS6KA5 421.0
XRCC5 416.0
APP 410.0
PSMA4 403.0
POLR3F 400.0
NOD1 331.0
POLR2K 272.0
ATG5 260.0
NFASC 228.0
RPS27A 210.0
PTK2 195.0
SNAP25 147.0
ORMDL3 131.0
C8A 101.0
PTPRB 86.0
HSP90B1 71.0
TTR 46.0
MRE11 41.0
CD44 39.0
ATP6V1H 11.0
DYNLL1 -62.0
HLA-C -81.0
NFAM1 -128.0
IKBIP -168.0
TIMP2 -171.0
DNAJC13 -185.0
PTX3 -202.0
PSMB2 -211.0
CSNK2B -255.0
ANO6 -263.0
NOS2 -269.0
FCGR2A -286.0
HEBP2 -296.0
STK11IP -300.0
PSMD11 -313.0
BCL2L1 -324.0
HCK -352.0
PYGB -354.0
GCA -361.0
PSME2 -465.0
AGL -488.0
FGL2 -497.0
ATG7 -503.0
SOCS1 -543.0
DOCK1 -573.0
PGLYRP2 -575.0
YES1 -582.0
LAMTOR2 -585.0
ABCA13 -627.0
LAMTOR3 -634.0
TXK -664.0
PSMC3 -685.0
VAV2 -718.0
PSMB6 -723.0
PGAM1 -749.0
RAP1B -756.0
UBB -760.0
CFI -788.0
TNIP2 -792.0
BAIAP2 -809.0
ITK -841.0
MMP9 -947.0
TICAM2 -992.0
MUC7 -1012.0
HSPA1A -1041.0
PLCG2 -1059.0
C4A -1065.5
C4B -1065.5
VAPA -1067.0
CNN2 -1099.0
CST3 -1143.0
LIMK1 -1145.0
ARPC3 -1148.0
CHIT1 -1164.0
BPI -1180.0
IKBKE -1189.0
DEFB113 -1208.0
POLR3E -1244.0
SFTPA2 -1257.0
ITGB2 -1311.0
ARSB -1319.0
ATP6V0C -1338.0
NCKAP1 -1406.0
PSMB1 -1423.0
RAB18 -1428.0
FGG -1438.0
PSAP -1493.0
MUC21 -1564.0
N4BP1 -1567.0
PLA2G2A -1602.0
RIPK2 -1644.0
GALNS -1647.0
ITPR1 -1665.0
NOD2 -1699.0
A1BG -1703.0
JUN -1705.0
PRKACG -1720.0
MAP2K4 -1727.0
CD47 -1733.0
AAMP -1741.0
POLR3K -1805.0
RHOA -1807.0
NCKIPSD -1820.0
RAB4B -1825.0
CASP8 -1852.0
MYO1C -1897.0
ASAH1 -1920.0
ITCH -1950.0
RAB14 -1976.0
CLEC4C -1988.0
MAP2K7 -1992.0
UNC13D -1999.0
TAB2 -2005.0
RAB7A -2015.0
PSMA3 -2026.0
TMBIM1 -2041.0
TLR3 -2046.0
VPS35L -2048.0
RHOF -2055.0
SIGIRR -2059.0
CREBBP -2076.0
PRKCQ -2103.0
RAC1 -2129.0
CLEC4E -2152.0
ATP6V1A -2153.0
PTPRN2 -2185.0
NLRC5 -2245.0
C3AR1 -2289.0
PGLYRP3 -2297.0
NFATC1 -2302.0
ARHGAP9 -2314.0
WASF2 -2321.0
SUGT1 -2361.0
TOLLIP -2369.0
LAIR1 -2377.0
HGSNAT -2393.0
SERPINB3 -2398.0
MAP3K8 -2415.0
DEFB128 -2433.0
POLR3C -2453.0
MAPK14 -2455.0
GGH -2458.0
CHUK -2459.0
NCF4 -2462.0
NLRX1 -2468.0
REG3A -2490.0
ECSIT -2495.0
C4BPA -2517.0
DTX4 -2526.0
POLR3B -2535.0
TRAF3 -2552.0
WASF3 -2564.0
CFHR4 -2572.0
DSP -2574.0
CYFIP2 -2578.0
ATP8B4 -2580.0
DEFB126 -2588.0
MUC13 -2596.0
DNM2 -2651.0
APEH -2657.0
PSMB10 -2660.0
POLR2H -2702.0
NFKB1 -2712.0
CRISP3 -2784.0
DYNC1LI1 -2789.0
USP14 -2835.0
ABL1 -2852.0
GSDME -2970.0
DEFB134 -2972.0
PIK3C3 -2990.0
RAB10 -2993.0
RNF216 -3031.0
PDXK -3032.0
UBE2D2 -3044.0
CASP2 -3072.0
RASGRP4 -3112.0
PELI2 -3147.0
MAP2K3 -3173.0
POLR3G -3178.0
LAT2 -3206.0
DHX36 -3227.0
EEA1 -3244.0
IFNA21 -3262.0
CCR2 -3268.0
HSPA8 -3316.0
NLRC3 -3343.0
NCSTN -3348.0
ITPR3 -3377.0
CTNNB1 -3397.0
HLA-E -3435.0
ARPC2 -3442.0
CMTM6 -3468.0
AOC1 -3501.0
TAB1 -3531.0
CARD11 -3541.0
SIGLEC5 -3588.0
MLEC -3600.0
FAF2 -3623.0
NCK1 -3736.0
CAT -3737.0
NFATC3 -3739.0
C3 -3747.0
UBC -3749.0
NFKBIB -3754.0
BRI3 -3763.0
PTAFR -3776.0
UBR4 -3791.0
LTF -3815.0
RAB44 -3858.0
TSPAN14 -3910.0
SIGLEC9 -3918.0
DUSP4 -3920.0
ARL8A -3953.0
IGF2R -3975.0
MAPK7 -3992.0
S100B -4012.0
PPP3R1 -4013.0
CPNE1 -4042.0
PSMD6 -4053.0
PPP3CB -4085.0
SKP1 -4092.0
PAFAH1B2 -4096.0
IQGAP1 -4119.0
ATP6V0B -4166.0
OLFM4 -4173.0
CPB2 -4175.0
C6 -4209.0
PRKACA -4231.0
PSMA5 -4249.0
CARD9 -4251.0
FYN -4258.0
ATP8A1 -4261.0
MGST1 -4271.0
AP2A2 -4338.0
CAPZA1 -4341.0
S100A7A -4381.0
HLA-A -4407.0
PCBP2 -4446.0
KRAS -4450.0
COLEC10 -4454.0
TCN1 -4471.0
TRAF2 -4488.0
BPIFB2 -4518.0
CCT2 -4530.0
HSP90AA1 -4552.0
IRF3 -4584.0
CD36 -4590.0
CRK -4592.0
CRACR2A -4598.0
ATP6V1E1 -4605.0
NLRP4 -4611.0
PSMD8 -4639.0
GPI -4641.0
CAND1 -4642.0
NCKAP1L -4688.0
PSMD7 -4693.0
PSMA8 -4702.0
LAMP1 -4736.0
TXN -4777.0
PLD2 -4793.0
AP1M1 -4825.0
CNPY3 -4837.0
RNASE7 -4892.0
MUC6 -4921.0
MASP1 -4983.0
CEACAM1 -5012.0
ANXA2 -5015.0
ACLY -5075.0
PSMC4 -5080.0
POLR2L -5100.0
MUC17 -5103.0
PAK2 -5107.0
NFKB2 -5123.0
CYBA -5153.0
DSG1 -5168.0
IFNB1 -5185.0
GSDMD -5202.0
PTPRC -5207.0
TRIM56 -5208.0
MAP3K7 -5235.0
TREX1 -5239.0
OSTF1 -5341.0
CREB1 -5377.0
POLR2E -5379.0
MUC5AC -5386.0
IRF7 -5398.0
HRNR -5399.0
BIRC2 -5417.0
CD55 -5455.0
QPCT -5459.0
MMP25 -5470.0
TP53 -5513.0
ADGRE5 -5547.0
ATP6V1F -5612.0
NF2 -5613.0
DEFB132 -5625.0
ATP6V0A4 -5694.0
MAP2K1 -5708.0
TCIRG1 -5717.0
ICAM2 -5747.0
DEFB123 -5755.0
ITGAV -5756.0
DEFB115 -5758.0
BPIFB6 -5775.0
BPIFA1 -5795.0
ATP6V1C2 -5804.0
TLR1 -5855.0
HBB -5861.0
NEU1 -5862.0
RAF1 -5871.0
PTPN4 -5881.0
MUC5B -5892.0
QSOX1 -5900.0
CPPED1 -5911.0
UBE2D1 -5915.0
ATP11B -5940.0
TLR2 -5952.0
CAPN1 -5964.0
UBE2L6 -5974.0
FUCA1 -5987.0
PELI1 -5993.0
BPIFB4 -6026.0
SYNGR1 -6073.0
F2 -6090.0
ITLN1 -6096.0
SERPING1 -6100.0
YPEL5 -6106.0
GUSB -6108.0
HMGB1 -6150.0
TRIM32 -6160.0
CAMP -6161.0
CFL1 -6192.0
PSMC6 -6194.0
MVP -6204.0
ATAD3B -6206.0
MAP3K1 -6231.0
FRK -6247.0
SLC44A2 -6309.0
CDC34 -6359.0
GZMM -6361.0
PSMD9 -6362.0
CYFIP1 -6404.0
ARPC1B -6450.0
PPP2CB -6478.0
MAPK3 -6553.0
CYB5R3 -6599.0
ITGAX -6637.0
MIF -6670.0
FUCA2 -6682.0
MALT1 -6698.0
CYLD -6717.0
VTN -6724.0
LRRC7 -6747.0
RBSN -6795.0
UBE2M -6841.0
PTPN6 -6907.0
LRRC14 -6921.0
MAPK9 -6942.0
CRP -7025.0
BPIFA2 -7045.0
ATOX1 -7110.0
TICAM1 -7125.0
PLCG1 -7205.0
ATP6V1E2 -7227.0
PGM1 -7330.0
SNAP29 -7345.0
HMOX1 -7360.0
TKFC -7382.0
BST2 -7427.0
EP300 -7432.0
C1QB -7442.0
MYH9 -7450.0
DYNC1H1 -7456.0
PTGES2 -7468.0
DEFB116 -7494.0
JUP -7518.0
PSME3 -7537.0
ATP11A -7539.0
CEACAM8 -7554.0
DYNLT1 -7568.0
PRG3 -7711.0
PSMD1 -7718.0
TIFA -7799.0
COMMD9 -7840.0
RELB -7872.0
AGA -7880.0
DHX58 -7886.0
WASL -7917.0
PDAP1 -7930.0
PECAM1 -7976.0
VCP -7977.0
ACTR1B -7982.0
PIK3R4 -8003.0
HRAS -8010.0
MUC1 -8044.0
COLEC11 -8180.0
TLR5 -8181.0
KCNAB2 -8207.0
ARPC1A -8248.0
ATP6V0A2 -8267.0
LBP -8314.0
DEFB136 -8315.0
TRIM25 -8329.0
PLPP5 -8340.0
TMEM63A -8360.0
DEFB118 -8365.0
LY86 -8376.0
S100A1 -8392.0
RASGRP1 -8404.0
ADA2 -8412.0
ARPC5 -8477.0
MAN2B1 -8484.0
C2 -8502.0
EPPIN -8503.0
ATP6V1G3 -8545.0
MUC4 -8558.0
DPP7 -8585.0
CANT1 -8600.0
IKBKB -8649.0
IMPDH2 -8655.0
RAB3A -8669.0
PSMD12 -8730.0
PDPK1 -8775.0
UBA3 -8782.0
RELA -8787.0
ITGAM -8862.0
CD81 -8869.0
GLB1 -8890.0
CD4 -8892.0
SERPINB6 -8893.0
CALM1 -8933.0
PLA2G6 -9003.0
MUC3A -9021.0
ATF1 -9030.0
ARHGAP45 -9083.0
PSMD13 -9136.0
MS4A2 -9147.0
ACAA1 -9174.0
PSMF1 -9180.0
COMMD3 -9186.0
TIRAP -9206.0
KLRD1 -9224.0
DDX41 -9226.0
RIPK1 -9229.0
CDK13 -9252.0
SURF4 -9307.0
XRCC6 -9311.0
TRIM4 -9354.0
BRK1 -9368.0
CFB -9369.0
ALAD -9384.0
CAPZA2 -9409.0
EEF2 -9480.0
PROS1 -9491.0
RAB6A -9519.0
HTN3 -9529.0
ORM1 -9543.0
GAA -9671.0
MUCL1 -9705.0
CD247 -9763.0
HMOX2 -9842.0
USP18 -9852.0
LCK -9856.0
MUC16 -9904.0
CALML5 -10007.0
TMEM179B -10008.0
RNASET2 -10012.0
GRAP2 -10017.0
SAA1 -10073.0
SPTAN1 -10082.0
PSMB11 -10116.0
CSTB -10147.0
ALPK1 -10192.0
PPIE -10203.0
ATP6V0E1 -10214.0
PSME1 -10255.0
NDUFC2 -10268.0
PFKL -10275.0
LCP2 -10384.0
DEFB125 -10410.0
TRIM21 -10425.0
CPN2 -10445.0
TBC1D10C -10502.0
FPR1 -10573.0
CCR6 -10602.0
REG3G -10625.0
ART1 -10640.0
CD19 -10690.0
DEFB129 -10750.0
PSMD2 -10774.0
KRT1 -10820.0
TLR10 -10844.0
GNLY -10871.0
S100A7 -10968.0
LAT -11003.0
CD3G -11017.0
IFNA5 -11216.0


REACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

REACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX
381
set REACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX
setSize 85
pANOVA 0.000439
s.dist -0.221
p.adjustANOVA 0.0774



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC3 -11072.0
H3C3 -10752.0
H3C6 -10696.0
KMT2D -10466.0
H2BC26 -10276.0
H2AC7 -10188.5
H2BC7 -10188.5
TCF7 -10093.0
H2AC20 -10070.0
H2AC14 -9995.0
RUNX3 -9922.0
H3-4 -9817.0
H3C4 -9701.0
LEO1 -9537.0
SMARCA4 -9405.0
CDC73 -9111.0
TRRAP -9080.0
H2AC18 -9031.5
H2AC19 -9031.5
TERT -8587.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC3 -11072.0
H3C3 -10752.0
H3C6 -10696.0
KMT2D -10466.0
H2BC26 -10276.0
H2AC7 -10188.5
H2BC7 -10188.5
TCF7 -10093.0
H2AC20 -10070.0
H2AC14 -9995.0
RUNX3 -9922.0
H3-4 -9817.0
H3C4 -9701.0
LEO1 -9537.0
SMARCA4 -9405.0
CDC73 -9111.0
TRRAP -9080.0
H2AC18 -9031.5
H2AC19 -9031.5
TERT -8587.0
BCL9L -8517.0
H3C1 -8260.0
H2BC14 -8236.0
TLE4 -8174.0
H2AC8 -8007.0
H4C1 -7768.0
H2AX -7754.0
H2BC8 -7687.0
RUVBL1 -7570.0
H2BC21 -7485.0
H3C11 -7455.0
EP300 -7432.0
HDAC1 -6364.0
KAT5 -5557.0
H4C4 -5408.0
H2BC1 -5406.0
LEF1 -5292.0
RBBP5 -5151.0
H4C9 -5033.0
H3-3B -4811.0
PYGO2 -4124.0
H4C3 -3847.0
AXIN2 -3751.0
CTNNB1 -3397.0
H4C6 -2615.0
TCF4 -2426.0
H4C12 -2167.0
CREBBP -2076.0
H2BC12 -1743.0
H4C16 -1250.0
BCL9 -1166.0
H2AC4 -1132.0
H3C8 -1035.0
MYC -588.0
H4C11 -494.0
H2BC11 -106.0
H2BC9 36.5
H3C7 36.5
H2AZ2 203.0
H4C5 481.0
MEN1 573.0
H2BC10 1117.0
H2AJ 1474.0
H4C2 2031.0
TLE1 2044.0
H4C13 2526.0
H2BC17 2583.0
ASH2L 2779.0
H2BC15 3952.0
H2BC5 4154.0
H3C2 4334.0
TLE3 5603.0
H2BC6 5880.0
H3-3A 6189.0
TCF7L2 6574.0
H4C8 6856.0
TLE2 7058.0
TCF7L1 7948.0
H3C10 8230.0
PYGO1 8408.0
H2AZ1 8703.0
H2BC13 8750.0
H2AC6 9114.0
H2BC4 9890.0
H3C12 10509.0


REACTOME_CELL_CYCLE

REACTOME_CELL_CYCLE
190
set REACTOME_CELL_CYCLE
setSize 666
pANOVA 0.000471
s.dist -0.0794
p.adjustANOVA 0.0774



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC3 -11072.0
PRDM9 -10877.0
PSMD2 -10774.0
H3C3 -10752.0
H3C6 -10696.0
PIAS4 -10499.0
SYCP1 -10277.0
H2BC26 -10276.0
PSME1 -10255.0
AAAS -10252.0
UBE2V2 -10249.0
NUP188 -10190.0
H2AC7 -10188.5
H2BC7 -10188.5
CDC25B -10166.0
TUBA3D -10142.0
PSMB11 -10116.0
H2AC20 -10070.0
ZWILCH -10065.0
KIF2B -10034.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC3 -11072.0
PRDM9 -10877.0
PSMD2 -10774.0
H3C3 -10752.0
H3C6 -10696.0
PIAS4 -10499.0
SYCP1 -10277.0
H2BC26 -10276.0
PSME1 -10255.0
AAAS -10252.0
UBE2V2 -10249.0
NUP188 -10190.0
H2AC7 -10188.5
H2BC7 -10188.5
CDC25B -10166.0
TUBA3D -10142.0
PSMB11 -10116.0
H2AC20 -10070.0
ZWILCH -10065.0
KIF2B -10034.0
H2AC14 -9995.0
AKT2 -9950.0
E2F2 -9918.0
JAK2 -9917.0
GTSE1 -9876.0
POLD2 -9835.0
NCAPH2 -9831.0
H3-4 -9817.0
CLSPN -9799.0
H3C4 -9701.0
NDEL1 -9680.0
RNF168 -9652.0
PHF20 -9613.0
HERC2 -9585.0
MAPRE1 -9576.0
INCENP -9573.0
DYNLL2 -9535.0
SYCP2 -9526.0
KIF2A -9489.0
CCNE1 -9434.0
POLD1 -9280.0
PSMF1 -9180.0
PSMD13 -9136.0
SUN2 -9039.0
H2AC18 -9031.5
H2AC19 -9031.5
RRM2 -9014.0
CDC27 -8997.0
CEP72 -8985.0
PCNT -8980.0
RMI2 -8964.0
CEP41 -8908.0
RANGAP1 -8875.0
NUP153 -8786.0
PSMD12 -8730.0
TERF1 -8662.0
NEK2 -8647.0
CC2D1B -8633.0
TERT -8587.0
LIG1 -8555.0
DNA2 -8554.0
POLR2A -8553.0
ANAPC16 -8548.0
CHTF8 -8508.0
ESPL1 -8505.0
LEMD2 -8490.0
CSNK1D -8377.0
CENPA -8363.0
E2F6 -8334.0
RNF8 -8282.0
H3C1 -8260.0
PPP2R5A -8244.0
CEP57 -8242.0
H2BC14 -8236.0
CDK11A -8228.0
UBE2I -8199.0
CDKN2C -8158.0
CENPF -8132.0
HAUS5 -8108.0
SHQ1 -8050.0
H2AC8 -8007.0
DMC1 -7964.0
FKBPL -7933.0
CEP192 -7901.0
CDK11B -7862.0
POLD3 -7854.0
ESCO2 -7846.0
CDC26 -7831.0
NUP50 -7788.0
H4C1 -7768.0
H2AX -7754.0
PPP1R12B -7739.0
DYNC1I2 -7729.0
PSMD1 -7718.0
H2BC8 -7687.0
AKT1 -7654.0
TUBAL3 -7648.0
RUVBL1 -7570.0
PSME3 -7537.0
CCP110 -7536.0
H2BC21 -7485.0
DYNC1H1 -7456.0
H3C11 -7455.0
MYBL2 -7439.0
EP300 -7432.0
TEX12 -7430.0
PDS5B -7411.0
NUP214 -7399.0
PPP2R5E -7395.0
BIRC5 -7367.0
ACD -7311.5
LIN52 -7274.0
NPM1 -7226.0
POLR2B -7177.0
MAD1L1 -7160.0
PPP2R2D -7148.0
MCM7 -7138.0
TUBGCP6 -7129.0
RHNO1 -6956.0
PLK4 -6912.0
NSD2 -6909.0
MND1 -6876.0
SPC24 -6849.0
PAFAH1B1 -6772.0
POLE -6750.0
TUBGCP2 -6748.0
TERF2 -6723.0
NUP205 -6658.0
CHMP4A -6651.0
MIS18BP1 -6613.0
RAD9A -6607.0
UBE2S -6592.0
LIN9 -6575.0
MAPK3 -6553.0
PPP2CB -6478.0
LCMT1 -6472.0
BUB1B -6413.0
TOP2A -6403.0
HDAC1 -6364.0
PSMD9 -6362.0
RBL2 -6356.0
CABLES1 -6333.0
TUBGCP5 -6302.0
SSNA1 -6279.0
NCAPD2 -6263.0
ANAPC2 -6253.0
PSMC6 -6194.0
HAUS8 -6193.0
NDE1 -6187.0
CEP76 -6152.0
CLASP2 -6038.0
MSH5 -6034.0
ABRAXAS1 -6006.0
RPA1 -5995.0
SEC13 -5991.0
VPS4A -5971.0
DIDO1 -5961.0
UBE2D1 -5915.0
YWHAE -5897.0
ANKLE2 -5887.0
GOLGA2 -5882.0
TUBB2B -5782.0
YWHAH -5768.0
MAU2 -5746.0
FZR1 -5689.0
CHMP2B -5648.0
ANAPC11 -5597.0
GORASP1 -5575.0
KAT5 -5557.0
RAD51 -5528.0
TP53 -5513.0
CEP63 -5505.0
CHMP7 -5494.0
H4C4 -5408.0
H2BC1 -5406.0
ANKRD28 -5401.0
POLR2E -5379.0
NBN -5357.0
MDC1 -5348.0
CDC45 -5301.0
CNTRL -5234.0
MASTL -5147.0
POLR2L -5100.0
PSMC4 -5080.0
RSF1 -5040.0
H4C9 -5033.0
UIMC1 -4967.0
PPP1CB -4924.0
CEP43 -4867.0
LPIN3 -4852.0
ORC3 -4824.0
H3-3B -4811.0
NIPBL -4780.0
SEH1L -4759.0
PSMA8 -4702.0
PSMD7 -4693.0
SUN1 -4675.0
PRKCB -4672.0
PSMD8 -4639.0
DYRK1A -4629.0
CHTF18 -4621.0
CENPS -4559.0
HSP90AA1 -4552.0
HMMR -4540.0
MCM5 -4487.0
MAX -4447.0
CTDNEP1 -4429.0
ACTR1A -4420.0
CHMP4B -4410.0
ODF2 -4375.0
SGO2 -4356.0
PCM1 -4344.0
PRIM1 -4339.0
DBF4 -4307.0
POLR2J -4267.0
ANAPC4 -4266.0
PSMA5 -4249.0
PRKACA -4231.0
SYCP3 -4192.0
PIF1 -4180.0
RAB8A -4154.0
HAUS2 -4128.0
DYNC1LI2 -4101.0
SKP1 -4092.0
CENPK -4056.0
PSMD6 -4053.0
NUP107 -4043.0
CDKN1B -4033.0
POLE3 -3924.0
H4C3 -3847.0
CEP70 -3812.0
PMF1 -3793.0
EML4 -3784.0
UBC -3749.0
SUMO1 -3709.0
NUP88 -3684.0
POM121C -3656.0
MAD2L1 -3571.0
SMC3 -3481.0
SMC1B -3476.0
TUBB2A -3433.0
KIF2C -3428.0
CCND3 -3416.0
CEP250 -3379.0
SYCE1 -3369.0
STN1 -3344.0
CEP152 -3329.0
LEMD3 -3277.0
TUBA3C -3266.0
POT1 -3264.0
STAG1 -3209.0
TOPBP1 -3164.0
NSL1 -3144.0
SGO1 -3081.0
RAD51C -3047.0
SYCE2 -3046.0
TUBA1C -2997.0
CDC23 -2975.0
PPME1 -2966.0
NHP2 -2958.0
CENPJ -2940.0
MIS18A -2912.0
CSNK1E -2909.0
SYNE2 -2904.0
TAOK1 -2902.0
E2F1 -2893.0
TUBA1A -2863.0
ABL1 -2852.0
ATM -2840.0
RCC1 -2839.0
NUMA1 -2800.0
DYNC1LI1 -2789.0
PCNA -2763.0
PPP2R5C -2720.0
CDC14A -2709.0
POLR2H -2702.0
GAR1 -2665.0
PSMB10 -2660.0
NUP62 -2619.0
H4C6 -2615.0
CCND1 -2612.0
RPS27 -2513.0
WEE1 -2456.0
TUBB4A -2409.0
TOP3A -2386.0
RAN -2357.0
RPA2 -2350.0
CDK4 -2328.0
CHEK1 -2287.0
MCM6 -2263.0
PPP1R12A -2233.0
CDT1 -2218.0
CEP131 -2181.0
H4C12 -2167.0
NUP155 -2088.0
SFI1 -2028.0
PSMA3 -2026.0
CEP78 -2019.0
TFDP2 -1943.0
DHFR -1918.0
PDS5A -1884.0
CENPT -1873.0
ANAPC5 -1859.0
RFC2 -1857.0
NUP37 -1786.0
NUP42 -1775.0
FEN1 -1752.0
CDCA8 -1749.0
TPR -1744.0
H2BC12 -1743.0
CENPC -1535.0
VRK1 -1501.0
HUS1 -1475.0
CDKN2D -1460.0
LIN54 -1434.0
PSMB1 -1423.0
NEDD1 -1360.0
RCC2 -1321.0
CHMP2A -1298.0
AKT3 -1295.0
POLA2 -1268.0
H4C16 -1250.0
NUP58 -1232.0
SYNE1 -1177.0
H2AC4 -1132.0
CENPM -1131.0
TMPO -1115.0
RPA3 -1106.0
TYMS -1094.0
TUBGCP4 -1085.0
ATR -1075.0
NCAPG2 -1056.0
H3C8 -1035.0
BUB1 -1032.0
TUBA1B -1007.0
NUP93 -988.0
CENPO -908.0
CSNK2A2 -889.0
HAUS3 -886.0
GINS4 -862.0
CTC1 -853.0
MCM8 -830.0
RTEL1 -797.0
NUP85 -780.0
UBB -760.0
POLE2 -740.0
PSMB6 -723.0
CEP164 -710.0
CCNB1 -695.0
PSMC3 -685.0
FBXL7 -678.0
SKA2 -657.0
MLH3 -640.0
CCNE2 -607.0
MYC -588.0
ORC2 -550.0
AURKA -540.0
EXO1 -533.0
KNTC1 -498.0
H4C11 -494.0
PSME2 -465.0
TINF2 -406.0
ALMS1 -387.0
MSH4 -382.0
RAD9B -363.0
PSMD11 -313.0
KIF20A -308.0
CSNK2B -255.0
OPTN -232.0
PSMB2 -211.0
ATRIP -199.0
CDK1 -191.0
ARPP19 -181.0
SPC25 -154.0
TPX2 -149.0
CDK6 -123.0
SPDL1 -110.0
H2BC11 -106.0
TERF2IP -95.0
GINS1 -67.0
DYNLL1 -62.0
TNPO1 -60.0
CKAP5 -58.0
ORC6 -36.0
H2BC9 36.5
H3C7 36.5
MRE11 41.0
NCAPD3 74.0
PRIM2 76.0
RUVBL2 158.0
H2AZ2 203.0
WRAP53 205.0
RPS27A 210.0
YWHAB 216.0
BRCA1 231.0
YWHAG 239.0
SIRT2 240.0
POLR2K 272.0
CDK2 273.0
TFDP1 291.0
SPAST 320.0
MCPH1 343.0
PSMA4 403.0
GINS2 432.0
POLR2F 466.0
H4C5 481.0
ORC4 511.0
PPP2R1A 545.0
E2F4 567.0
ORC5 586.0
BARD1 611.0
CDC16 614.0
RFC4 617.0
NUP98 621.0
NDC1 715.0
CDC25C 725.0
RFC3 775.0
CDKN2A 802.0
BLZF1 902.0
HAUS4 922.0
TUBB4B 988.0
PSMC3IP 1082.0
CLASP1 1087.0
H2BC10 1117.0
RFC5 1138.0
POLD4 1139.0
CDC7 1160.0
PPP2R5B 1217.0
NEK7 1242.0
TUBB 1258.0
PKMYT1 1259.0
RAB1A 1272.0
SMC2 1301.0
MAPK1 1304.0
MLH1 1361.0
LBR 1365.0
ORC1 1370.0
PSMB9 1422.0
CDK5RAP2 1425.0
H2AJ 1474.0
PRKCA 1517.0
BANF1 1527.0
B9D2 1534.0
CHMP6 1587.0
PSMD5 1604.0
DCTN3 1620.0
PSME4 1640.0
MDM4 1693.0
NCAPG 1701.0
NEK9 1703.0
TUBG1 1796.0
AJUBA 1829.0
CENPN 1849.0
FBXL18 1883.0
FOXM1 1946.0
KPNB1 1994.0
PPP2R2A 2016.0
DAXX 2017.0
H4C2 2031.0
PPP2R5D 2036.0
PPP6R3 2078.0
HSPA2 2109.0
VRK2 2124.0
RAB1B 2183.0
PTTG1 2190.0
RAD50 2206.0
ANAPC10 2226.0
NUP210 2253.0
MNAT1 2265.0
KMT5A 2285.0
NUDC 2293.0
RAD17 2339.0
NUP160 2353.0
PSMB5 2383.0
YWHAZ 2423.0
GINS3 2432.0
POLE4 2477.0
CDKN1A 2479.0
SMARCA5 2520.0
OIP5 2522.0
H4C13 2526.0
MZT2A 2538.0
NCAPH 2579.0
H2BC17 2583.0
WRN 2634.0
SRC 2638.0
MDM2 2701.0
ZW10 2728.0
RAB2A 2739.0
RB1 2745.0
BUB3 2773.0
GORASP2 2798.0
PSMD3 2823.0
CDC20 2843.0
PPP6C 2856.0
MCM10 2896.0
CENPQ 2898.0
MCM4 2914.0
PPP2R1B 2977.0
PLK1 3043.0
TEN1 3051.0
RBL1 3094.0
NUP35 3117.0
LPIN1 3122.0
CCNH 3184.0
NINL 3228.0
ESCO1 3240.0
PRKAR2B 3261.0
CENPU 3268.0
POLR2I 3271.0
ZNF385A 3283.0
POM121 3294.0
CDC6 3318.0
GMNN 3332.0
TUBGCP3 3344.0
PCBP4 3354.0
HSP90AB1 3410.0
REC8 3421.0
WAPL 3427.0
PSMC5 3435.0
POLR2C 3538.0
CENPP 3571.0
BABAM2 3586.0
PSMD4 3652.0
CDK7 3661.0
CEP135 3662.0
KIF23 3671.0
CLIP1 3707.0
CENPL 3729.0
SKP2 3746.0
DCTN1 3760.0
MIS12 3772.0
PSMA7 3774.0
E2F5 3777.0
RFC1 3816.0
SET 3840.0
TP53BP1 3925.0
CHEK2 3950.0
H2BC15 3952.0
RBX1 3985.0
BORA 3989.0
XPO1 4049.0
NDC80 4060.0
GSK3B 4099.0
PSMC1 4146.0
H2BC5 4154.0
NME7 4189.0
PSMD14 4205.0
UBE2E1 4252.0
DSCC1 4262.0
RAD1 4287.0
AHCTF1 4292.0
H3C2 4334.0
CCND2 4346.0
MCM3 4424.0
RANBP2 4443.0
LMNA 4450.0
HAUS1 4455.0
ANAPC1 4551.0
ANAPC7 4566.0
PSMB4 4596.0
PPP1CC 4640.0
HJURP 4780.0
LYN 4807.0
CENPH 4868.0
SDCCAG8 4878.0
SMC4 4934.0
BLM 4939.0
TK1 5016.0
BTRC 5091.0
YWHAQ 5097.0
USO1 5107.0
RAD21 5122.0
SEM1 5155.0
NUP54 5163.0
DYNC1I1 5245.0
AKAP9 5256.0
IST1 5285.0
COP1 5386.0
RBBP4 5414.0
CEP290 5498.0
MZT1 5619.0
CCNA2 5812.0
NUF2 5817.0
NOP10 5826.0
HAUS6 5843.0
ITGB3BP 5844.0
H2BC6 5880.0
NUP43 5884.0
RMI1 5934.0
CCNB2 5960.0
CDC25A 5984.0
CENPW 6157.0
H3-3A 6189.0
PPP2CA 6363.0
PSMB8 6380.0
E2F3 6541.0
FBXW11 6554.0
TUBA8 6563.0
FBXO5 6566.0
RBBP8 6725.0
PSMC2 6774.0
CHMP3 6836.0
PSMA2 6848.0
H4C8 6856.0
CKS1B 6889.0
BABAM1 6905.0
RAE1 6911.0
TEX15 6962.0
POLR2D 7144.0
LMNB1 7206.0
CNEP1R1 7211.0
SYCE3 7261.0
DSN1 7300.0
BRCA2 7348.0
PTK6 7396.0
CDKN1C 7407.0
TUBB3 7518.0
STAG3 7541.0
UBA52 7581.0
ANAPC15 7605.0
TUBG2 7665.0
DCTN2 7748.0
TUBA4B 7781.0
NUP133 7783.0
LIN37 7848.0
BRIP1 7863.0
CDCA5 7994.0
PSMA1 8054.0
UBE2N 8089.0
NEK6 8105.0
TUBB1 8143.0
CENPE 8187.0
PSMB3 8195.0
H3C10 8230.0
KIF18A 8235.0
MCM2 8262.0
TUBA4A 8277.0
MZT2B 8299.0
PHLDA1 8355.0
SPO11 8429.0
CSNK2A1 8453.0
KNL1 8564.0
PSMB7 8601.0
CUL1 8619.0
H2AZ1 8703.0
PSMA6 8714.0
H2BC13 8750.0
CCNA1 8842.0
ENSA 8858.0
TUBB6 9036.0
POLR2G 9042.0
CDKN2B 9072.0
FKBP6 9094.0
UBE2C 9100.0
H2AC6 9114.0
SKA1 9260.0
CHMP4C 9291.0
AURKB 9646.0
ZWINT 9839.0
H2BC4 9890.0
TUBA3E 9950.0
SFN 10102.0
LPIN2 10167.0
TUBB8 10294.0
H3C12 10509.0


REACTOME_METABOLISM_OF_RNA

REACTOME_METABOLISM_OF_RNA
1313
set REACTOME_METABOLISM_OF_RNA
setSize 675
pANOVA 0.000472
s.dist -0.0789
p.adjustANOVA 0.0774



Top enriched genes

Top 20 genes
GeneID Gene Rank
GLE1 -10901
PSMD2 -10774
THOC3 -10593
RPL10L -10366
SNIP1 -10339
NOL12 -10274
PSME1 -10255
AAAS -10252
RPL22 -10230
PPIE -10203
PHAX -10200
NUP188 -10190
MTO1 -10120
PSMB11 -10116
MTERF4 -10103
U2AF2 -9924
ERCC2 -9851
RPL3L -9803
CTU2 -9749
CHERP -9742

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GLE1 -10901.0
PSMD2 -10774.0
THOC3 -10593.0
RPL10L -10366.0
SNIP1 -10339.0
NOL12 -10274.0
PSME1 -10255.0
AAAS -10252.0
RPL22 -10230.0
PPIE -10203.0
PHAX -10200.0
NUP188 -10190.0
MTO1 -10120.0
PSMB11 -10116.0
MTERF4 -10103.0
U2AF2 -9924.0
ERCC2 -9851.0
RPL3L -9803.0
CTU2 -9749.0
CHERP -9742.0
RTRAF -9732.0
TRMT44 -9694.0
DDX39B -9682.0
PRPF6 -9630.0
RPS14 -9594.0
SNRPB -9577.0
KHSRP -9565.0
TSR3 -9523.0
SAP18 -9501.0
TFIP11 -9484.0
RPS15 -9442.0
SRSF5 -9412.0
RBM28 -9341.0
TRMU -9313.0
URM1 -9255.0
DDX41 -9226.0
RPL37A -9220.0
GTF2H5 -9200.0
PSMF1 -9180.0
CNOT2 -9169.0
SKIC8 -9165.0
FIP1L1 -9152.0
PSMD13 -9136.0
TRMT13 -9104.0
ADAT3 -9098.0
DHX37 -9060.0
TGS1 -9058.0
TBL3 -8963.0
EIF4A3 -8959.0
FBL -8926.0
APOBEC3H -8918.0
YJU2 -8899.0
EXOSC3 -8891.0
CTNNBL1 -8873.0
PAN2 -8842.0
SMG1 -8835.0
CACTIN -8834.0
NT5C3B -8822.0
EPRS1 -8808.0
POLDIP3 -8796.0
NUP153 -8786.0
PSMD12 -8730.0
DDX6 -8608.0
POLR2A -8553.0
PUS7 -8524.0
RPP30 -8481.0
RPS5 -8455.0
TRDMT1 -8415.0
CSNK1D -8377.0
TSEN2 -8318.0
NOB1 -8288.0
XPOT -8285.0
HSPB1 -8280.0
UTP14C -8162.0
SNW1 -8150.0
TPRKB -8127.0
PRPF8 -8121.0
PABPC1 -8095.0
C9orf78 -8091.0
SF3A2 -8087.0
SNRNP27 -7935.0
RPL24 -7908.0
GPATCH1 -7896.0
NOL6 -7890.0
FCF1 -7879.0
XAB2 -7805.0
NUP50 -7788.0
PSMD1 -7718.0
SART1 -7713.0
CWF19L2 -7700.0
SDE2 -7696.0
AKT1 -7654.0
SNRNP40 -7650.0
SUGP1 -7640.0
SF1 -7624.0
SF3A1 -7601.0
RPS23 -7595.0
MRM1 -7561.0
PSME3 -7537.0
UTP20 -7523.0
PPIL2 -7503.0
THOC1 -7426.0
LENG1 -7406.0
NUP214 -7399.0
TRIT1 -7372.0
POP7 -7307.0
RPL19 -7259.0
MPHOSPH6 -7255.0
SF3B6 -7237.0
POLR2B -7177.0
SNU13 -7174.0
WDR4 -7107.0
UPF1 -7059.0
EDC4 -7041.0
LSM3 -7040.0
UTP18 -6985.0
YBX1 -6976.0
PNO1 -6964.0
SKIC2 -6919.0
NOL9 -6899.0
PPIG -6861.0
SYF2 -6857.0
DHX38 -6830.0
UPF3A -6804.0
NIP7 -6801.0
METTL14 -6703.0
HNRNPH1 -6688.0
PATL1 -6676.0
NUP205 -6658.0
UTP15 -6570.0
RCL1 -6554.0
DDX23 -6518.0
CPSF7 -6471.0
LTV1 -6427.0
SRSF11 -6411.0
DDX46 -6409.0
SRSF6 -6394.0
PSMD9 -6362.0
ELAVL1 -6300.0
EXOSC5 -6275.0
UTP4 -6246.0
CPSF6 -6216.0
PSMC6 -6194.0
RRP1 -6138.0
RPS29 -6101.0
BCAS2 -6091.0
ETF1 -6036.0
SEC13 -5991.0
SNUPN -5951.0
PAPOLA -5939.0
LSM5 -5934.0
BYSL -5916.0
RPL26L1 -5886.0
PUS3 -5883.0
CNOT3 -5807.0
SNRPD2 -5788.0
TUT7 -5764.0
SNRNP200 -5678.0
PNN -5615.0
PUS1 -5515.0
NOC4L -5486.0
CDKAL1 -5484.0
PDCD7 -5453.0
IMP4 -5404.0
POLR2E -5379.0
ZMAT2 -5351.0
HNRNPA1 -5336.0
TRMT1 -5316.0
RPS26 -5257.0
RTCB -5193.0
PRPF3 -5130.0
POLR2L -5100.0
ELAC2 -5097.0
PSMC4 -5080.0
BUD23 -5073.0
RPP25 -5059.0
NSRP1 -4976.0
RPS3A -4938.0
SRRM2 -4931.0
SMG5 -4920.0
CNOT4 -4919.0
RPL6 -4911.0
XRN2 -4898.0
PPWD1 -4884.0
THG1L -4879.0
NOL11 -4864.0
QTRT1 -4827.0
NOP14 -4821.0
FUS -4774.0
RNGTT -4770.0
SEH1L -4759.0
DDX20 -4751.0
EXOSC10 -4714.0
RBM17 -4711.0
PSMA8 -4702.0
U2AF1L4 -4698.0
PSMD7 -4693.0
RPP14 -4673.0
LSM11 -4664.0
PSMD8 -4639.0
RIOK3 -4634.0
THOC7 -4627.0
WDR18 -4626.0
RPS6 -4622.0
TUT4 -4542.0
CPSF4 -4529.0
TSEN34 -4511.0
TRMT61A -4468.0
GEMIN7 -4466.0
PCBP2 -4446.0
WDR70 -4440.0
PPP1R8 -4434.0
TRMT9B -4423.0
PRPF38A -4362.0
LSM6 -4343.0
TRA2B -4333.0
POP4 -4323.0
RPL41 -4291.0
GTF2F1 -4288.0
RPS3 -4268.0
POLR2J -4267.0
GCFC2 -4254.0
PSMA5 -4249.0
LSM1 -4213.0
SRRT -4205.0
POP1 -4105.0
CNOT1 -4091.0
NOP58 -4073.0
PSMD6 -4053.0
NUP107 -4043.0
FAU -4041.0
PRPF18 -4034.0
PRPF4 -4008.0
SF3B4 -4001.0
SF3B1 -3956.0
GEMIN4 -3944.0
EFTUD2 -3938.0
NCBP2 -3923.0
DDX21 -3912.0
SNRPG -3908.0
DCPS -3899.0
ADAR -3889.0
RPS15A -3879.0
RIOK2 -3794.0
SNRPE -3785.0
WDR12 -3780.0
MPHOSPH10 -3766.0
UBC -3749.0
KRR1 -3733.0
CPSF1 -3722.0
NUP88 -3684.0
POM121C -3656.0
RPS11 -3646.0
WDR46 -3636.0
EIF4E -3608.0
LCMT2 -3602.0
RNPC3 -3552.0
PRPF31 -3548.0
CLNS1A -3543.0
GTF2H1 -3451.0
ZFP36L1 -3411.0
TRMT12 -3404.0
NSUN2 -3389.0
GTPBP3 -3378.0
MTREX -3373.0
CNOT11 -3364.0
CSTF1 -3336.0
TFB1M -3335.0
HEATR1 -3317.0
HSPA8 -3316.0
UBL5 -3311.0
PARN -3265.0
MAGOHB -3261.0
EXOSC7 -3236.0
EXOSC6 -3208.0
MFAP1 -3138.0
CTU1 -3113.0
PAN3 -3065.0
DHX15 -3040.0
RPL13 -3022.0
NHP2 -2958.0
ALYREF -2943.0
CSNK1E -2909.0
CRNKL1 -2885.0
TSEN15 -2881.0
SNRNP70 -2855.0
RRP7A -2853.0
CNOT10 -2848.0
SUPT5H -2836.0
CNOT9 -2819.0
SRSF4 -2814.0
RBM5 -2776.0
POLR2H -2702.0
CCAR1 -2700.0
GAR1 -2665.0
PSMB10 -2660.0
NUP62 -2619.0
CNOT6 -2554.0
HNRNPR -2540.0
RRP36 -2531.0
RPS27 -2513.0
SNRNP25 -2503.0
SNRPB2 -2466.0
MAPK14 -2455.0
SRSF7 -2425.0
ZMAT5 -2405.0
PPIL3 -2391.0
HNRNPM -2370.0
RAN -2357.0
IGF2BP2 -2337.0
LUC7L3 -2277.0
PTBP1 -2259.0
SNRPC -2230.0
ALKBH8 -2194.0
NUP155 -2088.0
PSMA3 -2026.0
SKIC3 -2023.0
DCP1A -2014.0
TRMT10A -1955.0
DCAF13 -1951.0
WBP4 -1948.0
RPL18 -1942.0
SF3B3 -1937.0
IGF2BP1 -1902.0
CWC27 -1891.0
TSR1 -1864.0
NUP37 -1786.0
TXNL4A -1781.0
NUP42 -1775.0
A1CF -1773.0
PABPN1 -1747.0
TPR -1744.0
GTF2F2 -1683.0
RBM39 -1669.0
POP5 -1628.0
EIF4A1 -1562.0
TCERG1 -1553.0
TYW1 -1540.0
PRMT5 -1468.0
PSMB1 -1423.0
AQR -1414.0
QTRT2 -1286.0
SYMPK -1236.0
NUP58 -1232.0
DDX49 -1219.0
TRMT11 -1201.0
PLRG1 -1103.0
DDX42 -1054.0
APOBEC3C -1051.0
RPS8 -1044.0
HSPA1A -1041.0
NUP93 -988.0
CHTOP -986.0
WDR33 -973.0
DDX5 -968.0
RPL26 -958.0
RPL21 -953.0
SRSF3 -945.0
CWC22 -919.0
RPLP2 -896.0
NXT1 -888.0
RPLP0 -801.0
ERI1 -786.0
NUP85 -780.0
FTSJ3 -777.0
UBB -760.0
PSMB6 -723.0
RPL31 -712.0
PSMC3 -685.0
GTF2H4 -651.0
FAM32A -647.0
LSM2 -549.0
RPL36AL -512.5
RPP21 -510.0
THADA -507.0
PSME2 -465.0
CASC3 -424.0
NSUN4 -379.0
ZCRB1 -368.0
PSMD11 -313.0
CWC15 -299.0
BUD31 -279.0
RPPH1 -219.0
PSMB2 -211.0
CNOT6L -195.0
CLP1 -90.0
TNPO1 -60.0
RPP40 -49.0
RPS27L -42.0
PPIL4 -41.0
RPL5 -25.0
SMG8 -3.0
SNRPD3 4.0
SENP3 8.0
MRM3 56.0
TRNT1 60.0
RPSA 85.0
CPSF2 95.0
HNRNPF 154.0
WDR77 169.0
RPS27A 210.0
YWHAB 216.0
HNRNPA2B1 217.0
EXOSC4 218.0
RPS18 225.0
TEX10 243.0
POLR2K 272.0
RPL9 293.0
SF3A3 305.0
MRM2 313.0
LSM7 318.0
LSM10 370.0
PSMA4 403.0
SMG6 405.0
SRSF1 438.0
POLR2F 466.0
NCL 516.0
PPP2R1A 545.0
ISG20L2 546.0
ZNF830 570.0
NUP98 621.0
FAM98B 635.0
SNRNP35 649.0
HNRNPU 677.0
RPL23 697.0
WDR75 711.0
NDC1 715.0
RPL7 753.0
NSUN6 769.0
RPS2 787.0
RPL14 799.0
UPF2 809.0
FYTTD1 811.0
RBM42 848.0
TRMT6 853.0
EIF4G1 889.0
EDC3 908.0
PUF60 935.0
BMS1 1021.0
RPL30 1060.0
SNRPA1 1162.0
CDC40 1311.0
EXOSC9 1332.0
WTAP 1380.0
PSMB9 1422.0
SMU1 1423.0
USP39 1457.0
PRKCA 1517.0
GTF2H3 1518.0
PSMD5 1604.0
METTL1 1626.0
PSME4 1640.0
ISY1 1657.0
RPS7 1676.0
DUS2 1784.0
WDR3 1805.0
CSTF2T 1814.0
RPS19 1918.0
PRCC 1996.0
PRKRIP1 2010.0
NOP56 2015.0
PPP2R2A 2016.0
DIMT1 2026.0
PRPF40A 2075.0
RPS10 2082.0
PRORP 2083.0
EXOSC8 2126.0
RPS12 2164.0
RPS21 2188.0
DHX16 2191.0
DNAJC8 2218.0
HNRNPL 2231.0
OSGEP 2240.0
NUP210 2253.0
MNAT1 2265.0
EBNA1BP2 2271.0
WDR36 2273.0
SRRM1 2303.0
NUP160 2353.0
TYW5 2362.0
PSMB5 2383.0
THOC5 2403.0
YWHAZ 2423.0
PCBP1 2457.0
MAPKAPK2 2481.0
RPL35A 2508.0
WBP11 2515.0
RPL18A 2540.0
WDR43 2593.0
CSTF3 2624.0
SF3B2 2629.0
EIF4B 2652.0
TRMT112 2720.0
RNPS1 2756.0
TSEN54 2765.0
PSMD3 2823.0
XRN1 2827.0
TRMT5 2864.0
RPP38 2889.0
RPL34 2908.0
RPL35 2913.0
RBM25 2990.0
RPS20 3000.0
RPL4 3012.0
HNRNPC 3064.0
SLU7 3098.0
PELP1 3108.0
NUP35 3117.0
CCNH 3184.0
RPL11 3232.0
C1D 3245.0
DHX9 3257.0
POLR2I 3271.0
POM121 3294.0
PRPF19 3307.0
RIOK1 3329.0
U2SURP 3368.0
GNL3 3374.0
SMG7 3422.0
CNOT8 3431.0
PSMC5 3435.0
CWC25 3460.0
POLR2C 3538.0
TRMT10C 3548.0
EXOSC2 3560.0
SNRNP48 3582.0
UTP6 3639.0
PSMD4 3652.0
CDK7 3661.0
HBS1L 3681.0
DDX47 3709.0
MAPK11 3751.0
IMP3 3756.0
PSMA7 3774.0
RPL27 3820.0
SET 3840.0
RPL13A 3845.5
METTL3 3860.0
LSM4 3901.0
CPSF3 4025.0
XPO1 4049.0
HNRNPA3 4098.0
PSMC1 4146.0
PNRC2 4194.0
HNRNPK 4199.0
PSMD14 4205.0
RPL15 4228.0
DDX52 4249.0
SRSF9 4417.0
RANBP2 4443.0
RBM22 4465.0
PSMB4 4596.0
GEMIN5 4625.0
RPL39L 4698.0
DCP2 4721.0
RBM7 4729.0
SMG9 4747.0
RBM8A 4753.0
ADARB1 4761.0
GSPT1 4762.0
NCBP1 4784.0
EIF4A2 4825.0
BOP1 4876.0
RPS25 4925.0
SNRPN 4927.0
DHX35 4951.0
CNOT7 4988.0
ZNF473 4997.0
RPS9 5010.0
BUD13 5049.0
SRSF2 5129.0
SEM1 5155.0
NUP54 5163.0
RPL28 5172.0
ADAT1 5246.0
SNRPA 5360.0
TNKS1BP1 5474.0
DIS3 5475.0
RPS16 5553.0
IK 5554.0
GEMIN6 5693.0
RPL22L1 5729.0
ZBTB8OS 5746.0
NOP10 5826.0
PCF11 5848.0
SLBP 5851.0
NUP43 5884.0
RPS24 6102.0
DDX1 6138.0
ZC3H11A 6231.0
DDX39A 6241.0
C2orf49 6283.0
SNRPD1 6287.0
RPL7A 6303.0
DCP1B 6342.0
PPP2CA 6363.0
PSMB8 6380.0
IGF2BP3 6569.0
HNRNPD 6616.0
UTP3 6630.0
RPL12 6702.0
RNMT 6728.0
PSMC2 6774.0
PSMA2 6848.0
RPS13 6875.0
RAE1 6911.0
RPL37 6912.0
RPL23A 6953.0
APOBEC2 6977.0
SARNP 7037.0
PES1 7076.0
APOBEC1 7088.0
POLR2D 7144.0
RPL29 7214.0
PDCD11 7216.0
TYW3 7255.0
RPL3 7305.0
SNRPF 7315.0
RPL32 7322.0
TP53RK 7454.0
CDC5L 7467.0
PAIP1 7491.0
PPIL1 7525.0
RRP9 7543.0
UBA52 7581.0
ANP32A 7593.0
ERCC3 7596.0
SRSF10 7602.0
RPL8 7608.0
NOP2 7630.0
SMNDC1 7664.0
EMG1 7693.0
RPL36 7752.0
PHF5A 7769.0
NUP133 7783.0
NAT10 7895.0
RPL38 7924.0
APOBEC4 8046.0
PSMA1 8054.0
EXOSC1 8099.0
ZFP36 8101.0
SRSF12 8166.0
NUDT21 8190.0
PSMB3 8195.0
SMN1 8254.5
SMN2 8254.5
MAGOH 8311.0
ADAT2 8327.0
RPL17 8465.0
ACIN1 8503.0
PSMB7 8601.0
RPS28 8686.0
PSMA6 8714.0
CCDC12 8757.0
LSM8 8801.0
DHX8 8843.0
RPL27A 8956.0
PRKCD 9030.0
POLR2G 9042.0
UTP25 9051.0
TRMT61B 9111.0
NXF1 9131.0
PPIH 9349.0
PWP2 9387.0
RPLP1 9515.0
THUMPD1 9596.0
GEMIN2 9665.0
UTP11 9708.0
THOC6 9810.0
APOBEC3A 9841.0
APOBEC3B 9991.0
RPL10A 10030.0
SRSF8 10038.0
SF3B5 10147.0
TNFSF13 10170.0


REACTOME_DNA_REPAIR

REACTOME_DNA_REPAIR
1168
set REACTOME_DNA_REPAIR
setSize 321
pANOVA 0.000788
s.dist -0.109
p.adjustANOVA 0.118



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC3 -11072.0
PIAS4 -10499.0
H2BC26 -10276.0
UBE2V2 -10249.0
PPIE -10203.0
H2AC7 -10188.5
H2BC7 -10188.5
H2AC20 -10070.0
H2AC14 -9995.0
ERCC2 -9851.0
POLD2 -9835.0
H3-4 -9817.0
CLSPN -9799.0
RNF168 -9652.0
HERC2 -9585.0
ADPRS -9580.0
RNF4 -9539.0
SUMO2 -9534.0
ACTR8 -9452.0
FANCA -9431.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC3 -11072.0
PIAS4 -10499.0
H2BC26 -10276.0
UBE2V2 -10249.0
PPIE -10203.0
H2AC7 -10188.5
H2BC7 -10188.5
H2AC20 -10070.0
H2AC14 -9995.0
ERCC2 -9851.0
POLD2 -9835.0
H3-4 -9817.0
CLSPN -9799.0
RNF168 -9652.0
HERC2 -9585.0
ADPRS -9580.0
RNF4 -9539.0
SUMO2 -9534.0
ACTR8 -9452.0
FANCA -9431.0
XPC -9366.0
SIRT6 -9353.0
XRCC6 -9311.0
POLD1 -9280.0
GTF2H5 -9200.0
H2AC18 -9031.5
H2AC19 -9031.5
RMI2 -8964.0
UVSSA -8917.0
YY1 -8726.0
TERF1 -8662.0
LIG1 -8555.0
DNA2 -8554.0
POLR2A -8553.0
PARP1 -8387.0
TRIM25 -8329.0
RNF8 -8282.0
H2BC14 -8236.0
UBE2I -8199.0
PIAS3 -8143.0
PNKP -8128.0
H2AC8 -8007.0
VCP -7977.0
RAD52 -7959.0
APBB1 -7928.0
EYA2 -7899.0
MCRS1 -7889.0
POLD3 -7854.0
PPP5C -7850.0
XAB2 -7805.0
H4C1 -7768.0
H2AX -7754.0
H2BC8 -7687.0
RAD18 -7671.0
RUVBL1 -7570.0
ALKBH3 -7509.0
H2BC21 -7485.0
EP300 -7432.0
XRCC2 -7347.0
ACD -7311.5
POLR2B -7177.0
RHNO1 -6956.0
COPS7A -6949.0
NSD2 -6909.0
INO80 -6751.0
POLE -6750.0
TERF2 -6723.0
USP7 -6707.0
TIMELESS -6646.0
RAD9A -6607.0
MGMT -6582.0
ERCC4 -6548.0
NFRKB -6419.0
UNG -6157.0
UBE2B -6115.0
ABRAXAS1 -6006.0
RPA1 -5995.0
UBE2L6 -5974.0
POLH -5972.0
XRCC1 -5898.0
COPS3 -5740.0
KDM4B -5696.0
MUS81 -5590.0
INO80E -5576.0
ACTL6A -5563.0
KAT5 -5557.0
RAD51 -5528.0
GPS1 -5522.0
TP53 -5513.0
H4C4 -5408.0
H2BC1 -5406.0
POLR2E -5379.0
NBN -5357.0
MDC1 -5348.0
DCLRE1C -5204.0
INO80D -5106.0
POLR2L -5100.0
H4C9 -5033.0
ASCC2 -4995.0
UIMC1 -4967.0
TIPIN -4942.0
RAD51D -4806.0
POLN -4731.0
ELL -4716.0
TDP1 -4696.0
ASCC1 -4671.0
OGG1 -4654.0
UBE2T -4600.0
FAAP100 -4599.0
DDB1 -4563.0
CENPS -4559.0
LIG3 -4480.0
FAN1 -4319.0
POLR2J -4267.0
COPS6 -3982.0
SMUG1 -3948.0
POLE3 -3924.0
ASCC3 -3866.0
MSH3 -3860.0
H4C3 -3847.0
POLM -3750.0
UBC -3749.0
UFD1 -3740.0
CUL4A -3734.0
SUMO1 -3709.0
KDM4A -3560.0
ERCC6 -3495.0
GTF2H1 -3451.0
INO80B -3287.0
POT1 -3264.0
TOPBP1 -3164.0
RAD51C -3047.0
FAAP24 -2976.0
ABL1 -2852.0
ATM -2840.0
NEIL3 -2773.0
PCNA -2763.0
POLR2H -2702.0
H4C6 -2615.0
MUTYH -2479.0
REV3L -2421.0
TOP3A -2386.0
USP1 -2364.0
RPA2 -2350.0
BAP1 -2307.0
CHEK1 -2287.0
ACTR5 -2227.0
H4C12 -2167.0
NTHL1 -2122.0
NPLOC4 -2104.0
RAD23B -2036.0
EYA1 -1962.0
NHEJ1 -1953.0
KPNA2 -1894.0
RFC2 -1857.0
FEN1 -1752.0
H2BC12 -1743.0
ERCC8 -1680.0
TCEA1 -1654.0
ERCC5 -1643.0
HUS1 -1475.0
AQR -1414.0
MAD2L2 -1383.0
POLK -1351.0
POLQ -1281.0
H4C16 -1250.0
EME2 -1224.0
H2AC4 -1132.0
RPA3 -1106.0
ATR -1075.0
DDB2 -1046.0
PALB2 -890.0
SPRTN -871.0
RTEL1 -797.0
UBB -760.0
RCHY1 -746.0
POLE2 -740.0
GTF2H4 -651.0
EXO1 -533.0
H4C11 -494.0
COPS5 -435.0
TINF2 -406.0
FAAP20 -404.0
RAD9B -363.0
TDP2 -240.0
PARP2 -209.0
ATRIP -199.0
COPS7B -170.0
H2BC11 -106.0
TERF2IP -95.0
H2BC9 36.5
MRE11 41.0
TFPT 54.0
COPS4 89.0
H2AZ2 203.0
RPS27A 210.0
BRCA1 231.0
POLR2K 272.0
CDK2 273.0
XRCC5 416.0
POLR2F 466.0
H4C5 481.0
RAD51B 496.0
ZNF830 570.0
BARD1 611.0
RFC4 617.0
POLL 676.0
REV1 762.0
RFC3 775.0
PRKDC 786.0
NEIL2 868.0
DCLRE1A 981.0
H2BC10 1117.0
RFC5 1138.0
POLD4 1139.0
FANCC 1210.0
WDR48 1299.0
MLH1 1361.0
H2AJ 1474.0
EYA4 1501.0
GTF2H3 1518.0
BAZ1B 1529.0
ISY1 1657.0
FANCI 1901.0
SUMO3 1932.0
H4C2 2031.0
POLI 2053.0
COPS8 2067.0
XRCC4 2096.0
PCLAF 2098.0
RAD50 2206.0
TDG 2234.0
PAXIP1 2259.0
MNAT1 2265.0
UBA7 2283.0
FANCD2 2338.0
RAD17 2339.0
USP45 2476.0
POLE4 2477.0
SMARCA5 2520.0
H4C13 2526.0
RIF1 2527.0
H2BC17 2583.0
WRN 2634.0
MSH2 2642.0
MAPK8 2729.0
RAD51AP1 2923.0
FTO 2975.0
CCNH 3184.0
MBD4 3198.0
POLR2I 3271.0
PRPF19 3307.0
GEN1 3323.0
POLR2C 3538.0
PMS2 3566.0
BABAM2 3586.0
SLX4 3596.0
CDK7 3661.0
RFC1 3816.0
LIG4 3868.0
TP53BP1 3925.0
CHEK2 3950.0
H2BC15 3952.0
RBX1 3985.0
EME1 4012.0
PPP4C 4091.0
H2BC5 4154.0
PARG 4188.0
USP10 4284.0
RAD1 4287.0
ALKBH5 4442.0
FANCL 4614.0
DTL 4835.0
MPG 4862.0
FANCF 4865.0
POLB 4873.0
COPS2 4894.0
BLM 4939.0
FANCM 5053.0
SEM1 5155.0
XPA 5310.0
XRCC3 5596.0
USP43 5641.0
CCNA2 5812.0
H2BC6 5880.0
INO80C 5883.0
RMI1 5934.0
DCLRE1B 5979.0
SPIDR 6014.0
PIAS1 6280.0
RNF111 6411.0
UBXN1 6538.0
ISG15 6588.0
RBBP8 6725.0
H4C8 6856.0
BABAM1 6905.0
CHD1L 7049.0
ERCC1 7111.0
EYA3 7131.0
POLR2D 7144.0
BRCA2 7348.0
HMGN1 7398.0
ACTB 7403.0
UBA52 7581.0
ERCC3 7596.0
PPP4R2 7704.0
ALKBH2 7737.0
BRIP1 7863.0
APEX1 7941.0
UBE2N 8089.0
FANCE 8142.0
FANCG 8384.0
MSH6 8667.0
H2AZ1 8703.0
H2BC13 8750.0
CCNA1 8842.0
NEIL1 8905.0
POLR2G 9042.0
H2AC6 9114.0
RAD23A 9456.0
H2BC4 9890.0


REACTOME_PKMTS_METHYLATE_HISTONE_LYSINES

REACTOME_PKMTS_METHYLATE_HISTONE_LYSINES
549
set REACTOME_PKMTS_METHYLATE_HISTONE_LYSINES
setSize 64
pANOVA 0.00086
s.dist -0.241
p.adjustANOVA 0.118



Top enriched genes

Top 20 genes
GeneID Gene Rank
KMT2B -11022
PRDM9 -10877
H3C3 -10752
H3C6 -10696
KMT2D -10466
H3C4 -9701
DOT1L -9559
RELA -8787
NSD3 -8764
SMYD2 -8343
H3C1 -8260
KMT5C -8004
PRDM16 -7839
H4C1 -7768
SETD3 -7548
WDR5 -7515
H3C11 -7455
ATF7IP -7154
KMT2E -7079
NSD2 -6909

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
KMT2B -11022.0
PRDM9 -10877.0
H3C3 -10752.0
H3C6 -10696.0
KMT2D -10466.0
H3C4 -9701.0
DOT1L -9559.0
RELA -8787.0
NSD3 -8764.0
SMYD2 -8343.0
H3C1 -8260.0
KMT5C -8004.0
PRDM16 -7839.0
H4C1 -7768.0
SETD3 -7548.0
WDR5 -7515.0
H3C11 -7455.0
ATF7IP -7154.0
KMT2E -7079.0
NSD2 -6909.0
EHMT2 -6790.0
SETDB1 -6393.0
EHMT1 -5545.0
H4C4 -5408.0
RBBP5 -5151.0
NFKB2 -5123.0
SETD1A -5060.0
H4C9 -5033.0
EZH2 -4861.0
H4C3 -3847.0
AEBP2 -3220.0
NFKB1 -2712.0
H4C6 -2615.0
KMT2C -2208.0
H4C12 -2167.0
ASH1L -2144.0
KMT5B -2034.0
SETD2 -1362.0
H4C16 -1250.0
NSD1 -1249.0
H3C8 -1035.0
H4C11 -494.0
SETD7 -399.0
SMYD3 -276.0
H3C7 36.5
H4C5 481.0
SETDB2 842.0
SUV39H2 888.0
EED 1128.0
KMT2A 1144.0
SETD1B 1562.0
MECOM 1933.0
H4C2 2031.0
KMT5A 2285.0
SUZ12 2417.0
DPY30 2505.0
H4C13 2526.0
ASH2L 2779.0
H3C2 4334.0
RBBP4 5414.0
SETD6 6705.0
H4C8 6856.0
H3C10 8230.0
H3C12 10509.0


REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES

REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES
394
set REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES
setSize 30
pANOVA 0.00149
s.dist -0.335
p.adjustANOVA 0.175



Top enriched genes

Top 20 genes
GeneID Gene Rank
CD3D -11230
CD3G -11017
LAT -11003
LCP2 -10384
GRAP2 -10017
LCK -9856
CD247 -9763
ZAP70 -9263
HLA-DQB2 -9117
CD4 -8892
EVL -8755
HLA-DRB5 -8437
CD3E -8056
CD101 -7808
PLCG1 -7205
PAK2 -5107
ENAH -4741
NCK1 -3736
HLA-DQA1 -3443
HLA-DRB1 -2919

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CD3D -11230
CD3G -11017
LAT -11003
LCP2 -10384
GRAP2 -10017
LCK -9856
CD247 -9763
ZAP70 -9263
HLA-DQB2 -9117
CD4 -8892
EVL -8755
HLA-DRB5 -8437
CD3E -8056
CD101 -7808
PLCG1 -7205
PAK2 -5107
ENAH -4741
NCK1 -3736
HLA-DQA1 -3443
HLA-DRB1 -2919
PLCG2 -1059
ITK -841
HLA-DQA2 1416
HLA-DQB1 1530
PAK1 3361
HLA-DRA 5174
HLA-DPB1 5364
HLA-DPA1 8191
FYB1 8814
VASP 10280


REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA

REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA
1146
set REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA
setSize 263
pANOVA 0.00159
s.dist -0.113
p.adjustANOVA 0.175



Top enriched genes

Top 20 genes
GeneID Gene Rank
GLE1 -10901
THOC3 -10593
SNIP1 -10339
AAAS -10252
PPIE -10203
NUP188 -10190
U2AF2 -9924
CHERP -9742
DDX39B -9682
PRPF6 -9630
SNRPB -9577
SAP18 -9501
TFIP11 -9484
SRSF5 -9412
DDX41 -9226
FIP1L1 -9152
EIF4A3 -8959
YJU2 -8899
CTNNBL1 -8873
CACTIN -8834

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GLE1 -10901
THOC3 -10593
SNIP1 -10339
AAAS -10252
PPIE -10203
NUP188 -10190
U2AF2 -9924
CHERP -9742
DDX39B -9682
PRPF6 -9630
SNRPB -9577
SAP18 -9501
TFIP11 -9484
SRSF5 -9412
DDX41 -9226
FIP1L1 -9152
EIF4A3 -8959
YJU2 -8899
CTNNBL1 -8873
CACTIN -8834
POLDIP3 -8796
NUP153 -8786
POLR2A -8553
SNW1 -8150
PRPF8 -8121
C9orf78 -8091
SF3A2 -8087
SNRNP27 -7935
GPATCH1 -7896
XAB2 -7805
NUP50 -7788
SART1 -7713
CWF19L2 -7700
SDE2 -7696
SNRNP40 -7650
SUGP1 -7640
SF1 -7624
SF3A1 -7601
PPIL2 -7503
THOC1 -7426
LENG1 -7406
NUP214 -7399
SF3B6 -7237
POLR2B -7177
SNU13 -7174
LSM3 -7040
YBX1 -6976
PPIG -6861
SYF2 -6857
DHX38 -6830
METTL14 -6703
HNRNPH1 -6688
NUP205 -6658
DDX23 -6518
CPSF7 -6471
SRSF11 -6411
DDX46 -6409
SRSF6 -6394
CPSF6 -6216
BCAS2 -6091
SEC13 -5991
PAPOLA -5939
LSM5 -5934
SNRPD2 -5788
SNRNP200 -5678
PNN -5615
PDCD7 -5453
POLR2E -5379
ZMAT2 -5351
HNRNPA1 -5336
PRPF3 -5130
POLR2L -5100
NSRP1 -4976
SRRM2 -4931
PPWD1 -4884
FUS -4774
SEH1L -4759
RBM17 -4711
U2AF1L4 -4698
THOC7 -4627
CPSF4 -4529
PCBP2 -4446
WDR70 -4440
PPP1R8 -4434
PRPF38A -4362
LSM6 -4343
TRA2B -4333
GTF2F1 -4288
POLR2J -4267
GCFC2 -4254
SRRT -4205
NUP107 -4043
PRPF18 -4034
PRPF4 -4008
SF3B4 -4001
SF3B1 -3956
EFTUD2 -3938
NCBP2 -3923
SNRPG -3908
SNRPE -3785
CPSF1 -3722
NUP88 -3684
POM121C -3656
EIF4E -3608
RNPC3 -3552
PRPF31 -3548
MTREX -3373
CSTF1 -3336
HSPA8 -3316
UBL5 -3311
MAGOHB -3261
MFAP1 -3138
DHX15 -3040
ALYREF -2943
CRNKL1 -2885
SNRNP70 -2855
SRSF4 -2814
RBM5 -2776
POLR2H -2702
CCAR1 -2700
NUP62 -2619
HNRNPR -2540
SNRNP25 -2503
SNRPB2 -2466
SRSF7 -2425
ZMAT5 -2405
PPIL3 -2391
HNRNPM -2370
LUC7L3 -2277
PTBP1 -2259
SNRPC -2230
NUP155 -2088
WBP4 -1948
SF3B3 -1937
CWC27 -1891
NUP37 -1786
TXNL4A -1781
NUP42 -1775
PABPN1 -1747
TPR -1744
GTF2F2 -1683
RBM39 -1669
TCERG1 -1553
AQR -1414
SYMPK -1236
NUP58 -1232
PLRG1 -1103
DDX42 -1054
NUP93 -988
CHTOP -986
WDR33 -973
DDX5 -968
SRSF3 -945
CWC22 -919
NXT1 -888
NUP85 -780
FAM32A -647
LSM2 -549
CASC3 -424
ZCRB1 -368
CWC15 -299
BUD31 -279
CLP1 -90
PPIL4 -41
SNRPD3 4
CPSF2 95
HNRNPF 154
HNRNPA2B1 217
POLR2K 272
SF3A3 305
LSM7 318
SRSF1 438
POLR2F 466
ZNF830 570
NUP98 621
SNRNP35 649
HNRNPU 677
NDC1 715
FYTTD1 811
RBM42 848
PUF60 935
SNRPA1 1162
CDC40 1311
WTAP 1380
SMU1 1423
USP39 1457
ISY1 1657
CSTF2T 1814
PRCC 1996
PRKRIP1 2010
PRPF40A 2075
DHX16 2191
DNAJC8 2218
HNRNPL 2231
NUP210 2253
SRRM1 2303
NUP160 2353
THOC5 2403
PCBP1 2457
WBP11 2515
CSTF3 2624
SF3B2 2629
RNPS1 2756
RBM25 2990
HNRNPC 3064
SLU7 3098
NUP35 3117
DHX9 3257
POLR2I 3271
POM121 3294
PRPF19 3307
U2SURP 3368
CWC25 3460
POLR2C 3538
SNRNP48 3582
METTL3 3860
LSM4 3901
CPSF3 4025
HNRNPA3 4098
HNRNPK 4199
SRSF9 4417
RANBP2 4443
RBM22 4465
RBM7 4729
RBM8A 4753
NCBP1 4784
SNRPN 4927
DHX35 4951
BUD13 5049
SRSF2 5129
NUP54 5163
SNRPA 5360
IK 5554
PCF11 5848
SLBP 5851
NUP43 5884
ZC3H11A 6231
DDX39A 6241
SNRPD1 6287
HNRNPD 6616
RAE1 6911
SARNP 7037
POLR2D 7144
SNRPF 7315
CDC5L 7467
PPIL1 7525
SRSF10 7602
SMNDC1 7664
PHF5A 7769
NUP133 7783
SRSF12 8166
NUDT21 8190
MAGOH 8311
ACIN1 8503
CCDC12 8757
LSM8 8801
DHX8 8843
POLR2G 9042
NXF1 9131
PPIH 9349
THOC6 9810
SRSF8 10038
SF3B5 10147


REACTOME_TRNA_PROCESSING

REACTOME_TRNA_PROCESSING
1147
set REACTOME_TRNA_PROCESSING
setSize 105
pANOVA 0.0016
s.dist -0.178
p.adjustANOVA 0.175



Top enriched genes

Top 20 genes
GeneID Gene Rank
AAAS -10252
NUP188 -10190
MTO1 -10120
CTU2 -9749
RTRAF -9732
TRMT44 -9694
TRMU -9313
URM1 -9255
TRMT13 -9104
ADAT3 -9098
EPRS1 -8808
NUP153 -8786
PUS7 -8524
RPP30 -8481
TRDMT1 -8415
TSEN2 -8318
XPOT -8285
TPRKB -8127
NUP50 -7788
NUP214 -7399

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
AAAS -10252
NUP188 -10190
MTO1 -10120
CTU2 -9749
RTRAF -9732
TRMT44 -9694
TRMU -9313
URM1 -9255
TRMT13 -9104
ADAT3 -9098
EPRS1 -8808
NUP153 -8786
PUS7 -8524
RPP30 -8481
TRDMT1 -8415
TSEN2 -8318
XPOT -8285
TPRKB -8127
NUP50 -7788
NUP214 -7399
TRIT1 -7372
POP7 -7307
WDR4 -7107
NUP205 -6658
SEC13 -5991
PUS3 -5883
PUS1 -5515
CDKAL1 -5484
TRMT1 -5316
RTCB -5193
ELAC2 -5097
RPP25 -5059
THG1L -4879
QTRT1 -4827
SEH1L -4759
RPP14 -4673
CPSF4 -4529
TSEN34 -4511
TRMT61A -4468
TRMT9B -4423
POP4 -4323
POP1 -4105
NUP107 -4043
CPSF1 -3722
NUP88 -3684
POM121C -3656
LCMT2 -3602
TRMT12 -3404
NSUN2 -3389
GTPBP3 -3378
CTU1 -3113
TSEN15 -2881
NUP62 -2619
RAN -2357
ALKBH8 -2194
NUP155 -2088
TRMT10A -1955
NUP37 -1786
NUP42 -1775
TPR -1744
POP5 -1628
TYW1 -1540
QTRT2 -1286
NUP58 -1232
TRMT11 -1201
NUP93 -988
NUP85 -780
RPP21 -510
THADA -507
RPPH1 -219
CLP1 -90
RPP40 -49
TRNT1 60
NUP98 621
FAM98B 635
NDC1 715
NSUN6 769
TRMT6 853
METTL1 1626
DUS2 1784
PRORP 2083
OSGEP 2240
NUP210 2253
NUP160 2353
TYW5 2362
TRMT112 2720
TSEN54 2765
TRMT5 2864
RPP38 2889
NUP35 3117
POM121 3294
TRMT10C 3548
RANBP2 4443
NUP54 5163
ADAT1 5246
ZBTB8OS 5746
NUP43 5884
DDX1 6138
C2orf49 6283
RAE1 6911
TYW3 7255
TP53RK 7454
NUP133 7783
ADAT2 8327
TRMT61B 9111


REACTOME_INTERLEUKIN_10_SIGNALING

REACTOME_INTERLEUKIN_10_SIGNALING
1039
set REACTOME_INTERLEUKIN_10_SIGNALING
setSize 43
pANOVA 0.00177
s.dist 0.275
p.adjustANOVA 0.182



Top enriched genes

Top 20 genes
GeneID Gene Rank
IL10 10442
CCL3 10370
LIF 10251
CCL5 10217
CCL2 10159
CCL19 9979
IL1B 9883
FCER2 9549
CSF2 9306
IL1A 9201
CXCL2 9177
TNFRSF1B 9070
CCR5 8539
IL1RN 8272
IL12B 7798
CD86 7651
IL18 7631
IL12A 7503
ICAM1 7356
IL1R2 6412

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
IL10 10442
CCL3 10370
LIF 10251
CCL5 10217
CCL2 10159
CCL19 9979
IL1B 9883
FCER2 9549
CSF2 9306
IL1A 9201
CXCL2 9177
TNFRSF1B 9070
CCR5 8539
IL1RN 8272
IL12B 7798
CD86 7651
IL18 7631
IL12A 7503
ICAM1 7356
IL1R2 6412
CCL22 6316
CXCL1 5052
CD80 5003
CSF1 4381
IL1R1 3841
CCL4 2930
CSF3 2670
PTGS2 642
IL10RB -747
IL10RA -1938
CCL20 -2331
STAT3 -2790
CCR2 -3268
PTAFR -3776
TNF -4900
JAK1 -5736
TYK2 -7280
CXCL8 -7825
CCR1 -9135
IL6 -9505
CXCL10 -10155
FPR1 -10573
TNFRSF1A -11079


REACTOME_MRNA_SPLICING

REACTOME_MRNA_SPLICING
1143
set REACTOME_MRNA_SPLICING
setSize 197
pANOVA 0.00197
s.dist -0.128
p.adjustANOVA 0.19



Top enriched genes

Top 20 genes
GeneID Gene Rank
SNIP1 -10339
PPIE -10203
U2AF2 -9924
CHERP -9742
DDX39B -9682
PRPF6 -9630
SNRPB -9577
SAP18 -9501
TFIP11 -9484
SRSF5 -9412
DDX41 -9226
EIF4A3 -8959
YJU2 -8899
CTNNBL1 -8873
CACTIN -8834
POLR2A -8553
SNW1 -8150
PRPF8 -8121
C9orf78 -8091
SF3A2 -8087

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SNIP1 -10339
PPIE -10203
U2AF2 -9924
CHERP -9742
DDX39B -9682
PRPF6 -9630
SNRPB -9577
SAP18 -9501
TFIP11 -9484
SRSF5 -9412
DDX41 -9226
EIF4A3 -8959
YJU2 -8899
CTNNBL1 -8873
CACTIN -8834
POLR2A -8553
SNW1 -8150
PRPF8 -8121
C9orf78 -8091
SF3A2 -8087
SNRNP27 -7935
GPATCH1 -7896
XAB2 -7805
SART1 -7713
CWF19L2 -7700
SDE2 -7696
SNRNP40 -7650
SUGP1 -7640
SF1 -7624
SF3A1 -7601
PPIL2 -7503
LENG1 -7406
SF3B6 -7237
POLR2B -7177
SNU13 -7174
LSM3 -7040
YBX1 -6976
PPIG -6861
SYF2 -6857
DHX38 -6830
HNRNPH1 -6688
DDX23 -6518
SRSF11 -6411
DDX46 -6409
SRSF6 -6394
BCAS2 -6091
LSM5 -5934
SNRPD2 -5788
SNRNP200 -5678
PNN -5615
PDCD7 -5453
POLR2E -5379
ZMAT2 -5351
HNRNPA1 -5336
PRPF3 -5130
POLR2L -5100
NSRP1 -4976
SRRM2 -4931
PPWD1 -4884
FUS -4774
RBM17 -4711
U2AF1L4 -4698
PCBP2 -4446
WDR70 -4440
PPP1R8 -4434
PRPF38A -4362
LSM6 -4343
TRA2B -4333
GTF2F1 -4288
POLR2J -4267
GCFC2 -4254
SRRT -4205
PRPF18 -4034
PRPF4 -4008
SF3B4 -4001
SF3B1 -3956
EFTUD2 -3938
NCBP2 -3923
SNRPG -3908
SNRPE -3785
RNPC3 -3552
PRPF31 -3548
MTREX -3373
HSPA8 -3316
UBL5 -3311
MAGOHB -3261
MFAP1 -3138
DHX15 -3040
ALYREF -2943
CRNKL1 -2885
SNRNP70 -2855
SRSF4 -2814
RBM5 -2776
POLR2H -2702
CCAR1 -2700
HNRNPR -2540
SNRNP25 -2503
SNRPB2 -2466
SRSF7 -2425
ZMAT5 -2405
PPIL3 -2391
HNRNPM -2370
LUC7L3 -2277
PTBP1 -2259
SNRPC -2230
WBP4 -1948
SF3B3 -1937
CWC27 -1891
TXNL4A -1781
GTF2F2 -1683
RBM39 -1669
TCERG1 -1553
AQR -1414
PLRG1 -1103
DDX42 -1054
DDX5 -968
SRSF3 -945
CWC22 -919
FAM32A -647
LSM2 -549
CASC3 -424
ZCRB1 -368
CWC15 -299
BUD31 -279
PPIL4 -41
SNRPD3 4
HNRNPF 154
HNRNPA2B1 217
POLR2K 272
SF3A3 305
LSM7 318
SRSF1 438
POLR2F 466
ZNF830 570
SNRNP35 649
HNRNPU 677
RBM42 848
PUF60 935
SNRPA1 1162
CDC40 1311
SMU1 1423
USP39 1457
ISY1 1657
PRCC 1996
PRKRIP1 2010
PRPF40A 2075
DHX16 2191
DNAJC8 2218
HNRNPL 2231
SRRM1 2303
PCBP1 2457
WBP11 2515
SF3B2 2629
RNPS1 2756
RBM25 2990
HNRNPC 3064
SLU7 3098
DHX9 3257
POLR2I 3271
PRPF19 3307
U2SURP 3368
CWC25 3460
POLR2C 3538
SNRNP48 3582
LSM4 3901
HNRNPA3 4098
HNRNPK 4199
SRSF9 4417
RBM22 4465
RBM7 4729
RBM8A 4753
NCBP1 4784
SNRPN 4927
DHX35 4951
BUD13 5049
SRSF2 5129
SNRPA 5360
IK 5554
SNRPD1 6287
HNRNPD 6616
POLR2D 7144
SNRPF 7315
CDC5L 7467
PPIL1 7525
SRSF10 7602
SMNDC1 7664
PHF5A 7769
SRSF12 8166
MAGOH 8311
ACIN1 8503
CCDC12 8757
LSM8 8801
DHX8 8843
POLR2G 9042
PPIH 9349
SRSF8 10038
SF3B5 10147


REACTOME_NEURONAL_SYSTEM

REACTOME_NEURONAL_SYSTEM
34
set REACTOME_NEURONAL_SYSTEM
setSize 388
pANOVA 0.00281
s.dist 0.0884
p.adjustANOVA 0.243



Top enriched genes

Top 20 genes
GeneID Gene Rank
GNG11 10395
TUBB8 10294
CHRNG 10264
KCNMB1 10115
KCNMB4 10026
TUBA3E 9950
CHRND 9948
KCNS1 9919
KCNA7 9721
HTR3A 9661
SLC18A3 9574
SLC1A1 9338
NBEA 9323
GLUL 9282
HOMER2 9151
KCNJ8 9037
TUBB6 9036
KCNV1 9010
KCNK13 8947
CAMK1 8921

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GNG11 10395
TUBB8 10294
CHRNG 10264
KCNMB1 10115
KCNMB4 10026
TUBA3E 9950
CHRND 9948
KCNS1 9919
KCNA7 9721
HTR3A 9661
SLC18A3 9574
SLC1A1 9338
NBEA 9323
GLUL 9282
HOMER2 9151
KCNJ8 9037
TUBB6 9036
KCNV1 9010
KCNK13 8947
CAMK1 8921
CHRNA4 8766
SLITRK1 8658
KCNA5 8553
GNAI2 8546
KCNK17 8498
KCNF1 8480
KCNA1 8360
PRKAR2A 8317
GJC1 8308
TUBA4A 8277
ARL6IP5 8242
GNB5 8214
TUBB1 8143
GRIN2C 8117
SLITRK3 8091
PLCB1 8087
KCNK3 7965
SLC17A7 7928
KCNA2 7914
KCNH3 7878
NRAS 7853
GAD2 7786
TUBA4B 7781
GRIA4 7765
CHRNA7 7755
GNG12 7733
GJD2 7707
SYT12 7656
GRM5 7649
NCALD 7648
SYT7 7558
ADCY8 7533
TUBB3 7518
CAMK2G 7517
KCNQ4 7510
CHRNA1 7466
LIN7A 7378
SLC38A1 7307
CHAT 7265
RPS6KA1 7236
KCNK16 7224
MYO6 7135
GLRB 7001
KCNJ9 6947
GNG8 6938
PRKCG 6850
KCNK4 6808
CACNA2D2 6786
PRKAB2 6773
GABRB2 6737
DLGAP1 6719
PRKACB 6694
PRKAG2 6661
TUBA8 6563
CPLX1 6551
CAMK2D 6489
GABRA2 6427
KCND2 6421
KCNB2 6403
KCNJ5 6286
NEFL 6069
GIT1 6045
KCNA4 6040
KCNK10 6031
IL1RAP 5861
GAD1 5854
HTR3E 5832
PRKAA2 5704
ADCY4 5698
GRIA1 5686
DLG2 5672
GABRR1 5615
KCNA3 5573
SLC1A3 5482
GRIN3B 5331
KCNA10 5149
KCNQ2 5147
PANX1 5121
CACNG2 5066
CHRNA2 5047
SLITRK5 5036
KCNJ15 4975
RTN3 4918
AP2A1 4899
CHRNB4 4883
GLRA1 4732
GABBR2 4705
GNG13 4682
LRRTM3 4622
GRIN1 4616
GRIP1 4601
KCNMA1 4529
ERBB4 4448
GRM1 4385
KCNQ5 4370
KCNH2 4345
GRIK4 4295
SHANK1 4294
SLC32A1 4254
UNC13B 4233
AKAP5 4207
DNAJC5 4193
LRFN1 4176
KCNQ3 4145
KCNN2 4083
EPB41L1 4075
NLGN2 4044
CACNB4 3937
KCNJ2 3920
SLC6A3 3839
SYT2 3801
LRFN2 3779
LRRTM2 3733
CACNB1 3648
HTR3B 3646
CACNA1E 3620
KCNAB1 3615
PRKAB1 3519
PRKAR1A 3464
ACHE 3385
GNAI1 3381
PRKAR2B 3261
RIMS1 3252
SLC1A2 3248
RASGRF2 3225
KCNC4 3152
KCNJ3 3120
GRIN2A 3068
LIN7B 3004
KCNK2 2989
GRIK1 2984
KCNH7 2920
HCN2 2865
NRXN2 2862
CACNB2 2842
KCNMB2 2802
KCNN3 2774
ALDH2 2722
MDM2 2701
RASGRF1 2675
KCNS2 2673
SRC 2638
DBNL 2524
GRIK2 2451
PPFIBP1 2446
LRRTM1 2407
GABRR3 2246
CACNA2D3 2239
PPFIA2 2192
BEGAIN 2176
KCNG3 2153
NRXN3 2151
SLC6A12 2137
GABRB3 2068
KCNJ6 2040
SLC6A11 2039
PPFIBP2 1878
DLGAP4 1841
ADCY1 1793
NRXN1 1763
NRG1 1728
GABRA4 1724
PTPRD 1679
ADCY6 1641
EPB41L2 1621
KCNH1 1609
KCNS3 1605
SLC38A2 1594
PRKCA 1517
STX1A 1418
ADCY2 1409
TSPOAP1 1362
KCNK9 1333
MAPK1 1304
GRIK3 1228
DLG4 1172
RPS6KA2 1136
ADCY5 1097
KCNC3 1029
KCNJ10 1025
TUBB4B 988
GRIN3A 812
SYT10 793
GABRR2 719
ABAT 670
AP2S1 663
KCNH5 658
GRIA2 467
KCNH8 277
KCNH4 150
SNAP25 147
GABRG2 134
CHRNB3 -78
SLC5A7 -105
NLGN1 -107
COMT -158
GABRA1 -201
GABRB1 -227
CACNG8 -256
NPTN -331
STXBP1 -369
KCNQ1 -431
GRIN2B -451
CACNA1B -571
GRIK5 -614
CACNA1A -621
ADCY9 -632
KCND3 -636
EPB41 -684
GNG2 -702
SYT1 -821
KCNK18 -843
GLS2 -847
SLC22A2 -850
GNG5 -891
PPFIA3 -971
TUBA1B -1007
GLS -1016
GLRA3 -1098
GNB3 -1123
GNG4 -1138
FLOT1 -1221
GNAT3 -1350
CHRNA3 -1377
SHANK2 -1388
HTR3D -1446
LRRTM4 -1483
SLC6A4 -1514
LRTOMT -1517
CAMK2B -1528
KCNJ11 -1531
GABRG3 -1607
SIPA1L1 -1659
PRKACG -1720
MAPT -1735
CHRNB2 -1817
NRGN -1843
KPNA2 -1894
KCNC1 -1946
GNAI3 -1954
DLG1 -1956
GRIN2D -1967
KCNV2 -2002
SLITRK6 -2021
NTRK3 -2106
RAC1 -2129
SYN2 -2131
SYN3 -2219
DLGAP2 -2335
TUBB4A -2409
SLC6A13 -2416
KCNA6 -2602
DLGAP3 -2747
APBA1 -2748
GABBR1 -2768
TUBA1A -2863
KCNK1 -2929
TUBA1C -2997
GNGT2 -3018
CACNG4 -3258
TUBA3C -3266
KCNH6 -3297
PRKAR1B -3310
HSPA8 -3316
KCNC2 -3323
CAMK4 -3380
TUBB2A -3433
HCN4 -3462
GNG7 -3536
KCNG1 -3569
KCNJ1 -3584
PPFIA4 -3666
CHRNA6 -3686
CHRNE -3762
KCNAB3 -3819
CAMK2A -3859
PRKAG1 -3878
LRFN4 -3927
LRRC4B -4076
KIF17 -4112
GNB2 -4115
GNG10 -4182
KCNN4 -4224
PRKACA -4231
GNAL -4314
AP2A2 -4338
PDLIM5 -4354
KRAS -4450
ABCC8 -4526
GNG3 -4555
PRKCB -4672
PPM1F -4771
HCN1 -4951
SLC18A2 -5009
PLCB3 -5028
KCNB1 -5052
SLC22A1 -5141
AP2B1 -5173
CAMKK1 -5206
SYT9 -5281
EPB41L3 -5282
GNB1 -5364
CREB1 -5377
NAAA -5452
PTPRS -5527
TUBB2B -5782
ARHGEF7 -5798
PRKAA1 -5901
KCNN1 -6134
ABCC9 -6407
CACNB3 -6537
MAPK3 -6553
APBA2 -6618
BCHE -6699
CAMKK2 -6714
PPFIA1 -6716
LRRC7 -6747
HCN3 -6761
PLCB2 -6769
FLOT2 -6820
KCNJ16 -6827
PICK1 -6828
PANX2 -7141
KCNJ12 -7220
PPM1E -7258
PTPRF -7286
SLC6A1 -7337
GNB4 -7354
APBA3 -7363
KCNK7 -7412
CHRNA5 -7475
SLC1A7 -7491
CACNG3 -7626
TUBAL3 -7648
GRIP2 -7763
GABRA5 -7782
KCNK6 -7881
KCNG4 -8009
HRAS -8010
AP2M1 -8109
GNGT1 -8140
SHARPIN -8175
ADCY3 -8198
KCNAB2 -8207
ALDH5A1 -8385
HOMER3 -8444
KCNMB3 -8515
RAB3A -8669
KCNJ4 -8773
PDPK1 -8775
ACTN2 -8895
CALM1 -8933
EPB41L5 -8952
GABRA6 -9177
CHRNA9 -9179
SLC1A6 -9245
HOMER1 -9290
ADCY7 -9295
VAMP2 -9335
NSF -9490
KCNG2 -9844
GJA10 -10036
TUBA3D -10142
LIN7C -10221
LRFN3 -10258
HTR3C -10329
KCNJ14 -10411
PRKAG3 -10928


REACTOME_HDACS_DEACETYLATE_HISTONES

REACTOME_HDACS_DEACETYLATE_HISTONES
548
set REACTOME_HDACS_DEACETYLATE_HISTONES
setSize 85
pANOVA 0.0029
s.dist -0.187
p.adjustANOVA 0.243



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC3 -11072.0
H3C3 -10752.0
H3C6 -10696.0
H2BC26 -10276.0
H2AC7 -10188.5
H2BC7 -10188.5
H2AC25 -10089.0
H2AC20 -10070.0
H2AC14 -9995.0
HMG20B -9890.0
H3C4 -9701.0
SAP18 -9501.0
H2AC18 -9031.5
H2AC19 -9031.5
HDAC10 -8983.0
H3C1 -8260.0
H2BC14 -8236.0
H2AC21 -8042.0
GPS2 -8018.0
H2AC8 -8007.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC3 -11072.0
H3C3 -10752.0
H3C6 -10696.0
H2BC26 -10276.0
H2AC7 -10188.5
H2BC7 -10188.5
H2AC25 -10089.0
H2AC20 -10070.0
H2AC14 -9995.0
HMG20B -9890.0
H3C4 -9701.0
SAP18 -9501.0
H2AC18 -9031.5
H2AC19 -9031.5
HDAC10 -8983.0
H3C1 -8260.0
H2BC14 -8236.0
H2AC21 -8042.0
GPS2 -8018.0
H2AC8 -8007.0
H4C1 -7768.0
H2BC8 -7687.0
H2BC21 -7485.0
H3C11 -7455.0
GATAD2A -7114.0
BRMS1 -7026.0
MTA1 -6546.0
SUDS3 -6371.0
HDAC1 -6364.0
NCOR1 -6111.0
H2AC1 -6019.0
CHD3 -5673.0
REST -5458.0
H4C4 -5408.0
H2BC1 -5406.0
MBD3 -5200.0
H4C9 -5033.0
RCOR1 -3905.0
H4C3 -3847.0
ARID4B -3376.0
H2AC15 -3334.0
HDAC3 -2692.0
H4C6 -2615.0
TBL1XR1 -2551.0
H4C12 -2167.0
KDM1A -2016.0
H2BC12 -1743.0
H4C16 -1250.0
H2AC4 -1132.0
H3C8 -1035.0
SAP30 -541.0
H4C11 -494.0
H2BC11 -106.0
H2BC9 36.5
H3C7 36.5
H4C5 481.0
SAP30L 1031.0
CHD4 1053.0
H2BC10 1117.0
MTA3 1224.0
H2AC12 1565.0
H2AC17 1568.0
PHF21A 1752.0
H4C2 2031.0
MTA2 2290.0
H4C13 2526.0
H2BC17 2583.0
GATAD2B 3828.0
H2BC15 3952.0
H2BC5 4154.0
H3C2 4334.0
NCOR2 4797.0
ARID4A 4800.0
RBBP4 5414.0
H2AC11 5446.0
H2AC13 5645.0
H2BC6 5880.0
HDAC2 6519.0
H2AC16 6664.0
H4C8 6856.0
H3C10 8230.0
H2BC13 8750.0
H2AC6 9114.0
H2BC4 9890.0
H3C12 10509.0


REACTOME_BASE_EXCISION_REPAIR

REACTOME_BASE_EXCISION_REPAIR
1164
set REACTOME_BASE_EXCISION_REPAIR
setSize 87
pANOVA 0.00296
s.dist -0.184
p.adjustANOVA 0.243



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC3 -11072.0
H2BC26 -10276.0
H2AC7 -10188.5
H2BC7 -10188.5
H2AC20 -10070.0
H2AC14 -9995.0
POLD2 -9835.0
H3-4 -9817.0
ADPRS -9580.0
POLD1 -9280.0
H2AC18 -9031.5
H2AC19 -9031.5
TERF1 -8662.0
LIG1 -8555.0
PARP1 -8387.0
H2BC14 -8236.0
PNKP -8128.0
H2AC8 -8007.0
POLD3 -7854.0
H4C1 -7768.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC3 -11072.0
H2BC26 -10276.0
H2AC7 -10188.5
H2BC7 -10188.5
H2AC20 -10070.0
H2AC14 -9995.0
POLD2 -9835.0
H3-4 -9817.0
ADPRS -9580.0
POLD1 -9280.0
H2AC18 -9031.5
H2AC19 -9031.5
TERF1 -8662.0
LIG1 -8555.0
PARP1 -8387.0
H2BC14 -8236.0
PNKP -8128.0
H2AC8 -8007.0
POLD3 -7854.0
H4C1 -7768.0
H2AX -7754.0
H2BC8 -7687.0
H2BC21 -7485.0
ACD -7311.5
POLE -6750.0
TERF2 -6723.0
UNG -6157.0
RPA1 -5995.0
XRCC1 -5898.0
H4C4 -5408.0
H2BC1 -5406.0
H4C9 -5033.0
OGG1 -4654.0
LIG3 -4480.0
SMUG1 -3948.0
POLE3 -3924.0
H4C3 -3847.0
POT1 -3264.0
NEIL3 -2773.0
PCNA -2763.0
H4C6 -2615.0
MUTYH -2479.0
RPA2 -2350.0
H4C12 -2167.0
NTHL1 -2122.0
RFC2 -1857.0
FEN1 -1752.0
H2BC12 -1743.0
H4C16 -1250.0
H2AC4 -1132.0
RPA3 -1106.0
POLE2 -740.0
H4C11 -494.0
TINF2 -406.0
PARP2 -209.0
H2BC11 -106.0
TERF2IP -95.0
H2BC9 36.5
H2AZ2 203.0
H4C5 481.0
RFC4 617.0
RFC3 775.0
NEIL2 868.0
H2BC10 1117.0
RFC5 1138.0
POLD4 1139.0
H2AJ 1474.0
H4C2 2031.0
TDG 2234.0
POLE4 2477.0
H4C13 2526.0
H2BC17 2583.0
MBD4 3198.0
RFC1 3816.0
H2BC15 3952.0
H2BC5 4154.0
PARG 4188.0
MPG 4862.0
POLB 4873.0
H2BC6 5880.0
H4C8 6856.0
APEX1 7941.0
H2AZ1 8703.0
H2BC13 8750.0
NEIL1 8905.0
H2AC6 9114.0
H2BC4 9890.0


REACTOME_CELL_CYCLE_MITOTIC

REACTOME_CELL_CYCLE_MITOTIC
1112
set REACTOME_CELL_CYCLE_MITOTIC
setSize 539
pANOVA 0.00377
s.dist -0.0729
p.adjustANOVA 0.295



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC3 -11072.0
PSMD2 -10774.0
H3C3 -10752.0
H3C6 -10696.0
H2BC26 -10276.0
PSME1 -10255.0
AAAS -10252.0
NUP188 -10190.0
H2AC7 -10188.5
H2BC7 -10188.5
CDC25B -10166.0
TUBA3D -10142.0
PSMB11 -10116.0
H2AC20 -10070.0
ZWILCH -10065.0
KIF2B -10034.0
H2AC14 -9995.0
AKT2 -9950.0
E2F2 -9918.0
JAK2 -9917.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC3 -11072.0
PSMD2 -10774.0
H3C3 -10752.0
H3C6 -10696.0
H2BC26 -10276.0
PSME1 -10255.0
AAAS -10252.0
NUP188 -10190.0
H2AC7 -10188.5
H2BC7 -10188.5
CDC25B -10166.0
TUBA3D -10142.0
PSMB11 -10116.0
H2AC20 -10070.0
ZWILCH -10065.0
KIF2B -10034.0
H2AC14 -9995.0
AKT2 -9950.0
E2F2 -9918.0
JAK2 -9917.0
GTSE1 -9876.0
POLD2 -9835.0
NCAPH2 -9831.0
H3-4 -9817.0
H3C4 -9701.0
NDEL1 -9680.0
MAPRE1 -9576.0
INCENP -9573.0
DYNLL2 -9535.0
KIF2A -9489.0
CCNE1 -9434.0
POLD1 -9280.0
PSMF1 -9180.0
PSMD13 -9136.0
H2AC18 -9031.5
H2AC19 -9031.5
RRM2 -9014.0
CDC27 -8997.0
CEP72 -8985.0
PCNT -8980.0
CEP41 -8908.0
RANGAP1 -8875.0
NUP153 -8786.0
PSMD12 -8730.0
NEK2 -8647.0
CC2D1B -8633.0
LIG1 -8555.0
DNA2 -8554.0
ANAPC16 -8548.0
ESPL1 -8505.0
LEMD2 -8490.0
CSNK1D -8377.0
CENPA -8363.0
E2F6 -8334.0
H3C1 -8260.0
PPP2R5A -8244.0
CEP57 -8242.0
H2BC14 -8236.0
CDK11A -8228.0
UBE2I -8199.0
CDKN2C -8158.0
CENPF -8132.0
HAUS5 -8108.0
H2AC8 -8007.0
FKBPL -7933.0
CEP192 -7901.0
CDK11B -7862.0
POLD3 -7854.0
ESCO2 -7846.0
CDC26 -7831.0
NUP50 -7788.0
H4C1 -7768.0
H2AX -7754.0
PPP1R12B -7739.0
DYNC1I2 -7729.0
PSMD1 -7718.0
H2BC8 -7687.0
AKT1 -7654.0
TUBAL3 -7648.0
PSME3 -7537.0
CCP110 -7536.0
H2BC21 -7485.0
DYNC1H1 -7456.0
H3C11 -7455.0
MYBL2 -7439.0
EP300 -7432.0
PDS5B -7411.0
NUP214 -7399.0
PPP2R5E -7395.0
BIRC5 -7367.0
LIN52 -7274.0
MAD1L1 -7160.0
PPP2R2D -7148.0
MCM7 -7138.0
TUBGCP6 -7129.0
PLK4 -6912.0
SPC24 -6849.0
PAFAH1B1 -6772.0
POLE -6750.0
TUBGCP2 -6748.0
NUP205 -6658.0
CHMP4A -6651.0
UBE2S -6592.0
LIN9 -6575.0
MAPK3 -6553.0
PPP2CB -6478.0
LCMT1 -6472.0
BUB1B -6413.0
TOP2A -6403.0
HDAC1 -6364.0
PSMD9 -6362.0
RBL2 -6356.0
CABLES1 -6333.0
TUBGCP5 -6302.0
SSNA1 -6279.0
NCAPD2 -6263.0
ANAPC2 -6253.0
PSMC6 -6194.0
HAUS8 -6193.0
NDE1 -6187.0
CEP76 -6152.0
CLASP2 -6038.0
RPA1 -5995.0
SEC13 -5991.0
VPS4A -5971.0
UBE2D1 -5915.0
YWHAE -5897.0
ANKLE2 -5887.0
GOLGA2 -5882.0
TUBB2B -5782.0
MAU2 -5746.0
FZR1 -5689.0
CHMP2B -5648.0
ANAPC11 -5597.0
GORASP1 -5575.0
TP53 -5513.0
CEP63 -5505.0
CHMP7 -5494.0
H4C4 -5408.0
H2BC1 -5406.0
CDC45 -5301.0
CNTRL -5234.0
MASTL -5147.0
PSMC4 -5080.0
H4C9 -5033.0
PPP1CB -4924.0
CEP43 -4867.0
LPIN3 -4852.0
ORC3 -4824.0
H3-3B -4811.0
NIPBL -4780.0
SEH1L -4759.0
PSMA8 -4702.0
PSMD7 -4693.0
PRKCB -4672.0
PSMD8 -4639.0
DYRK1A -4629.0
CENPS -4559.0
HSP90AA1 -4552.0
HMMR -4540.0
MCM5 -4487.0
MAX -4447.0
CTDNEP1 -4429.0
ACTR1A -4420.0
CHMP4B -4410.0
ODF2 -4375.0
SGO2 -4356.0
PCM1 -4344.0
PRIM1 -4339.0
DBF4 -4307.0
ANAPC4 -4266.0
PSMA5 -4249.0
PRKACA -4231.0
RAB8A -4154.0
HAUS2 -4128.0
DYNC1LI2 -4101.0
SKP1 -4092.0
CENPK -4056.0
PSMD6 -4053.0
NUP107 -4043.0
CDKN1B -4033.0
POLE3 -3924.0
H4C3 -3847.0
CEP70 -3812.0
PMF1 -3793.0
EML4 -3784.0
UBC -3749.0
SUMO1 -3709.0
NUP88 -3684.0
POM121C -3656.0
MAD2L1 -3571.0
SMC3 -3481.0
TUBB2A -3433.0
KIF2C -3428.0
CCND3 -3416.0
CEP250 -3379.0
CEP152 -3329.0
LEMD3 -3277.0
TUBA3C -3266.0
STAG1 -3209.0
NSL1 -3144.0
SGO1 -3081.0
TUBA1C -2997.0
CDC23 -2975.0
PPME1 -2966.0
CENPJ -2940.0
CSNK1E -2909.0
TAOK1 -2902.0
E2F1 -2893.0
TUBA1A -2863.0
ABL1 -2852.0
RCC1 -2839.0
NUMA1 -2800.0
DYNC1LI1 -2789.0
PCNA -2763.0
PPP2R5C -2720.0
CDC14A -2709.0
PSMB10 -2660.0
NUP62 -2619.0
H4C6 -2615.0
CCND1 -2612.0
RPS27 -2513.0
WEE1 -2456.0
TUBB4A -2409.0
RAN -2357.0
RPA2 -2350.0
CDK4 -2328.0
MCM6 -2263.0
PPP1R12A -2233.0
CDT1 -2218.0
CEP131 -2181.0
H4C12 -2167.0
NUP155 -2088.0
SFI1 -2028.0
PSMA3 -2026.0
CEP78 -2019.0
TFDP2 -1943.0
DHFR -1918.0
PDS5A -1884.0
CENPT -1873.0
ANAPC5 -1859.0
RFC2 -1857.0
NUP37 -1786.0
NUP42 -1775.0
FEN1 -1752.0
CDCA8 -1749.0
TPR -1744.0
H2BC12 -1743.0
CENPC -1535.0
VRK1 -1501.0
CDKN2D -1460.0
LIN54 -1434.0
PSMB1 -1423.0
NEDD1 -1360.0
RCC2 -1321.0
CHMP2A -1298.0
AKT3 -1295.0
POLA2 -1268.0
H4C16 -1250.0
NUP58 -1232.0
H2AC4 -1132.0
CENPM -1131.0
TMPO -1115.0
RPA3 -1106.0
TYMS -1094.0
TUBGCP4 -1085.0
NCAPG2 -1056.0
H3C8 -1035.0
BUB1 -1032.0
TUBA1B -1007.0
NUP93 -988.0
CENPO -908.0
CSNK2A2 -889.0
HAUS3 -886.0
GINS4 -862.0
MCM8 -830.0
NUP85 -780.0
UBB -760.0
POLE2 -740.0
PSMB6 -723.0
CEP164 -710.0
CCNB1 -695.0
PSMC3 -685.0
FBXL7 -678.0
SKA2 -657.0
CCNE2 -607.0
MYC -588.0
ORC2 -550.0
AURKA -540.0
KNTC1 -498.0
H4C11 -494.0
PSME2 -465.0
ALMS1 -387.0
PSMD11 -313.0
KIF20A -308.0
CSNK2B -255.0
OPTN -232.0
PSMB2 -211.0
CDK1 -191.0
ARPP19 -181.0
SPC25 -154.0
TPX2 -149.0
CDK6 -123.0
SPDL1 -110.0
H2BC11 -106.0
GINS1 -67.0
DYNLL1 -62.0
TNPO1 -60.0
CKAP5 -58.0
ORC6 -36.0
H2BC9 36.5
H3C7 36.5
NCAPD3 74.0
PRIM2 76.0
H2AZ2 203.0
RPS27A 210.0
YWHAG 239.0
SIRT2 240.0
CDK2 273.0
TFDP1 291.0
SPAST 320.0
MCPH1 343.0
PSMA4 403.0
GINS2 432.0
H4C5 481.0
ORC4 511.0
PPP2R1A 545.0
E2F4 567.0
ORC5 586.0
CDC16 614.0
RFC4 617.0
NUP98 621.0
NDC1 715.0
CDC25C 725.0
RFC3 775.0
CDKN2A 802.0
BLZF1 902.0
HAUS4 922.0
TUBB4B 988.0
CLASP1 1087.0
H2BC10 1117.0
RFC5 1138.0
POLD4 1139.0
CDC7 1160.0
PPP2R5B 1217.0
NEK7 1242.0
TUBB 1258.0
PKMYT1 1259.0
RAB1A 1272.0
SMC2 1301.0
MAPK1 1304.0
LBR 1365.0
ORC1 1370.0
PSMB9 1422.0
CDK5RAP2 1425.0
H2AJ 1474.0
PRKCA 1517.0
BANF1 1527.0
B9D2 1534.0
CHMP6 1587.0
PSMD5 1604.0
DCTN3 1620.0
PSME4 1640.0
NCAPG 1701.0
NEK9 1703.0
TUBG1 1796.0
AJUBA 1829.0
CENPN 1849.0
FBXL18 1883.0
FOXM1 1946.0
KPNB1 1994.0
PPP2R2A 2016.0
H4C2 2031.0
PPP2R5D 2036.0
VRK2 2124.0
RAB1B 2183.0
PTTG1 2190.0
ANAPC10 2226.0
NUP210 2253.0
MNAT1 2265.0
KMT5A 2285.0
NUDC 2293.0
NUP160 2353.0
PSMB5 2383.0
GINS3 2432.0
POLE4 2477.0
CDKN1A 2479.0
H4C13 2526.0
MZT2A 2538.0
NCAPH 2579.0
H2BC17 2583.0
SRC 2638.0
ZW10 2728.0
RAB2A 2739.0
RB1 2745.0
BUB3 2773.0
GORASP2 2798.0
PSMD3 2823.0
CDC20 2843.0
MCM10 2896.0
CENPQ 2898.0
MCM4 2914.0
PPP2R1B 2977.0
PLK1 3043.0
RBL1 3094.0
NUP35 3117.0
LPIN1 3122.0
CCNH 3184.0
NINL 3228.0
ESCO1 3240.0
PRKAR2B 3261.0
CENPU 3268.0
POM121 3294.0
CDC6 3318.0
GMNN 3332.0
TUBGCP3 3344.0
HSP90AB1 3410.0
WAPL 3427.0
PSMC5 3435.0
CENPP 3571.0
PSMD4 3652.0
CDK7 3661.0
CEP135 3662.0
KIF23 3671.0
CLIP1 3707.0
CENPL 3729.0
SKP2 3746.0
DCTN1 3760.0
MIS12 3772.0
PSMA7 3774.0
E2F5 3777.0
RFC1 3816.0
SET 3840.0
H2BC15 3952.0
RBX1 3985.0
BORA 3989.0
XPO1 4049.0
NDC80 4060.0
GSK3B 4099.0
PSMC1 4146.0
H2BC5 4154.0
NME7 4189.0
PSMD14 4205.0
UBE2E1 4252.0
AHCTF1 4292.0
H3C2 4334.0
CCND2 4346.0
MCM3 4424.0
RANBP2 4443.0
LMNA 4450.0
HAUS1 4455.0
ANAPC1 4551.0
ANAPC7 4566.0
PSMB4 4596.0
PPP1CC 4640.0
LYN 4807.0
CENPH 4868.0
SDCCAG8 4878.0
SMC4 4934.0
TK1 5016.0
BTRC 5091.0
USO1 5107.0
RAD21 5122.0
SEM1 5155.0
NUP54 5163.0
DYNC1I1 5245.0
AKAP9 5256.0
IST1 5285.0
RBBP4 5414.0
CEP290 5498.0
MZT1 5619.0
CCNA2 5812.0
NUF2 5817.0
HAUS6 5843.0
ITGB3BP 5844.0
H2BC6 5880.0
NUP43 5884.0
CCNB2 5960.0
CDC25A 5984.0
H3-3A 6189.0
PPP2CA 6363.0
PSMB8 6380.0
E2F3 6541.0
FBXW11 6554.0
TUBA8 6563.0
FBXO5 6566.0
PSMC2 6774.0
CHMP3 6836.0
PSMA2 6848.0
H4C8 6856.0
CKS1B 6889.0
RAE1 6911.0
LMNB1 7206.0
CNEP1R1 7211.0
DSN1 7300.0
PTK6 7396.0
CDKN1C 7407.0
TUBB3 7518.0
UBA52 7581.0
ANAPC15 7605.0
TUBG2 7665.0
DCTN2 7748.0
TUBA4B 7781.0
NUP133 7783.0
LIN37 7848.0
CDCA5 7994.0
PSMA1 8054.0
NEK6 8105.0
TUBB1 8143.0
CENPE 8187.0
PSMB3 8195.0
H3C10 8230.0
KIF18A 8235.0
MCM2 8262.0
TUBA4A 8277.0
MZT2B 8299.0
PHLDA1 8355.0
CSNK2A1 8453.0
KNL1 8564.0
PSMB7 8601.0
CUL1 8619.0
H2AZ1 8703.0
PSMA6 8714.0
H2BC13 8750.0
CCNA1 8842.0
ENSA 8858.0
TUBB6 9036.0
CDKN2B 9072.0
UBE2C 9100.0
H2AC6 9114.0
SKA1 9260.0
CHMP4C 9291.0
AURKB 9646.0
ZWINT 9839.0
H2BC4 9890.0
TUBA3E 9950.0
LPIN2 10167.0
TUBB8 10294.0
H3C12 10509.0


REACTOME_RMTS_METHYLATE_HISTONE_ARGININES

REACTOME_RMTS_METHYLATE_HISTONE_ARGININES
552
set REACTOME_RMTS_METHYLATE_HISTONE_ARGININES
setSize 72
pANOVA 0.00455
s.dist -0.193
p.adjustANOVA 0.331



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C3 -10752.0
H3C6 -10696.0
H2AC7 -10188.5
H2AC25 -10089.0
H2AC20 -10070.0
H2AC14 -9995.0
ARID2 -9935.0
JAK2 -9917.0
H3C4 -9701.0
SMARCA4 -9405.0
H2AC18 -9031.5
H2AC19 -9031.5
H3C1 -8260.0
SMARCB1 -8171.0
H2AC21 -8042.0
H2AC8 -8007.0
H4C1 -7768.0
H2AX -7754.0
PRMT6 -7699.0
ARID1A -7610.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C3 -10752.0
H3C6 -10696.0
H2AC7 -10188.5
H2AC25 -10089.0
H2AC20 -10070.0
H2AC14 -9995.0
ARID2 -9935.0
JAK2 -9917.0
H3C4 -9701.0
SMARCA4 -9405.0
H2AC18 -9031.5
H2AC19 -9031.5
H3C1 -8260.0
SMARCB1 -8171.0
H2AC21 -8042.0
H2AC8 -8007.0
H4C1 -7768.0
H2AX -7754.0
PRMT6 -7699.0
ARID1A -7610.0
WDR5 -7515.0
H3C11 -7455.0
ARID1B -6832.0
H2AC1 -6019.0
ACTL6A -5563.0
H4C4 -5408.0
H4C9 -5033.0
CARM1 -5002.0
SMARCD2 -4823.0
PRMT7 -4573.0
H4C3 -3847.0
PRMT1 -3846.0
H2AC15 -3334.0
PBRM1 -2949.0
H4C6 -2615.0
CCND1 -2612.0
CDK4 -2328.0
H4C12 -2167.0
PRMT5 -1468.0
H4C16 -1250.0
H2AC4 -1132.0
SMARCC1 -1105.0
H3C8 -1035.0
ACTL6B -917.0
H4C11 -494.0
DNMT3A -476.0
H3C7 36.5
WDR77 169.0
COPRS 178.0
H2AZ2 203.0
SMARCC2 236.0
H4C5 481.0
RPS2 787.0
H2AJ 1474.0
H2AC12 1565.0
H2AC17 1568.0
PRMT3 1890.0
H4C2 2031.0
SMARCE1 2503.0
H4C13 2526.0
SMARCD1 4142.0
H3C2 4334.0
H2AC11 5446.0
H2AC13 5645.0
SMARCA2 6082.0
H2AC16 6664.0
H4C8 6856.0
H3C10 8230.0
SMARCD3 8563.0
H2AZ1 8703.0
H2AC6 9114.0
H3C12 10509.0


REACTOME_DEVELOPMENTAL_BIOLOGY

REACTOME_DEVELOPMENTAL_BIOLOGY
76
set REACTOME_DEVELOPMENTAL_BIOLOGY
setSize 1115
pANOVA 0.00485
s.dist 0.05
p.adjustANOVA 0.331



Top enriched genes

Top 20 genes
GeneID Gene Rank
CEBPE 10560
H3C12 10509
SPI1 10508
KRT16 10471
KRTAP10-6 10427
SPRR2E 10392
TYROBP 10391
LCE1F 10376
KRT33B 10354
LCE4A 10322
TUBB8 10294
VASP 10280
CD72 10275
KRTAP4-11 10261
HOXA2 10233
KRTAP8-1 10232
NTN3 10089
KRT13 10088
RXRA 10047
RPL10A 10030

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CEBPE 10560.0
H3C12 10509.0
SPI1 10508.0
KRT16 10471.0
KRTAP10-6 10427.0
SPRR2E 10392.0
TYROBP 10391.0
LCE1F 10376.0
KRT33B 10354.0
LCE4A 10322.0
TUBB8 10294.0
VASP 10280.0
CD72 10275.0
KRTAP4-11 10261.0
HOXA2 10233.0
KRTAP8-1 10232.0
NTN3 10089.0
KRT13 10088.0
RXRA 10047.0
RPL10A 10030.0
KRTAP5-10 10003.0
TUBA3E 9950.0
MYF6 9926.0
KRT32 9908.0
KRT34 9907.0
IAPP 9901.0
H2BC4 9890.0
FOXL2 9829.0
EFNB3 9820.0
MAML1 9808.0
KRT3 9727.0
LCE3D 9677.0
LCE6A 9650.0
WT1 9645.0
COL9A3 9630.0
CNTN6 9561.0
MYL9 9523.0
RPLP1 9515.0
HOXD4 9491.0
PLXNA2 9451.0
KRTAP1-4 9438.0
DSG2 9429.0
VLDLR 9377.0
KRT72 9328.0
EPHA7 9281.0
EFNA2 9274.0
TBPL2 9273.0
ARTN 9257.0
SEMA4A 9241.0
SCN2B 9240.0
KRTAP6-2 9235.0
HOXB2 9230.0
PLXND1 9190.0
TGM5 9189.0
KRTAP9-2 9181.0
H2AC6 9114.0
FLRT3 9110.0
ADAM11 9106.0
POLR2G 9042.0
TUBB6 9036.0
KRTAP5-4 9031.0
WNT1 8966.0
KRT4 8964.0
RPL27A 8956.0
KRTAP26-1 8955.0
KRT33A 8950.0
KRTAP13-2 8949.0
LEFTY2 8930.0
RND1 8897.0
CSTA 8804.0
KRTAP19-1 8775.0
H2BC13 8750.0
MAFB 8746.0
PSMA6 8714.0
H2AZ1 8703.0
RPS28 8686.0
KRTAP29-1 8684.0
MED7 8653.0
LGI2 8625.0
KRT12 8616.0
MEF2D 8607.0
KRT14 8602.0
PSMB7 8601.0
EPHA2 8577.0
RARA 8570.0
SMARCD3 8563.0
AMH 8556.0
KRT5 8538.0
HHEX 8502.0
KRT76 8499.0
MYL12B 8493.0
FOXH1 8486.0
RPL17 8465.0
CSNK2A1 8453.0
ONECUT3 8440.0
LHX9 8412.0
CDH15 8392.0
LEFTY1 8353.0
PAX6 8329.0
NEUROD1 8326.0
PRKAR2A 8317.0
MAGOH 8311.0
GRB7 8300.0
TUBA4A 8277.0
COL4A4 8259.0
H3C10 8230.0
PSMB3 8195.0
LCE1A 8174.0
DKK1 8148.0
TUBB1 8143.0
NOTO 8138.0
DMRT1 8135.0
KRT80 8116.0
NEUROG3 8110.0
KRTAP22-1 8081.0
MIXL1 8079.0
EGFR 8078.0
KRTAP4-4 8064.0
PSMA1 8054.0
KRT7 8036.0
SPINK9 8014.0
UNC5B 8007.0
SPRR1B 7985.0
LCE2A 7933.0
RPL38 7924.0
ACVR2A 7872.0
NRAS 7853.0
LIMK2 7849.0
DSG3 7836.0
HOXD3 7834.0
SNAI1 7797.0
TUBA4B 7781.0
GSC 7760.0
NCAM1 7756.0
RPL36 7752.0
PLXNA4 7747.0
KRT85 7718.0
MYF5 7703.0
SHC1 7700.0
CAP1 7661.0
PERP 7641.0
ACTR2 7628.0
KRTAP11-1 7615.0
KRT79 7610.0
RPL8 7608.0
GFRA3 7595.0
UBA52 7581.0
EPHB3 7576.0
PFN1 7563.0
SPINK6 7561.0
HNF1B 7560.0
COL5A3 7559.0
SCN9A 7528.0
TBXT 7526.0
SPTA1 7524.0
TUBB3 7518.0
KRTAP21-2 7507.0
HNF4G 7404.0
ACTB 7403.0
RPL32 7322.0
RPL3 7305.0
KRTAP10-3 7285.0
PTF1A 7239.0
RPS6KA1 7236.0
RPL29 7214.0
NEO1 7209.0
KRT84 7196.0
CASP14 7193.0
DOK5 7170.0
CSF3R 7166.0
NRP1 7145.0
POLR2D 7144.0
KRTAP13-3 7106.0
SH3GL2 7098.0
SMAD2 7069.0
KRTAP5-5 7063.0
LCE3B 7059.0
PI3 7040.0
RPL23A 6953.0
DAB1 6941.0
KRT71 6923.0
RPL37 6912.0
RPS13 6875.0
KRT23 6865.0
H4C8 6856.0
PSMA2 6848.0
DPYSL2 6845.0
WNT10B 6840.0
WNT4 6810.0
GFI1 6807.0
RASA1 6797.0
GATA6 6796.0
FES 6791.0
PSMC2 6774.0
SCD5 6757.0
STX1B 6729.0
RPL12 6702.0
PRKACB 6694.0
ADGRV1 6654.0
KRTAP9-6 6645.0
SIAH2 6612.0
KLF4 6598.0
LYPLA2 6594.0
SCN3A 6587.0
KRT74 6564.0
TUBA8 6563.0
DSCAML1 6562.0
HDAC2 6519.0
KRT2 6497.0
PMP22 6473.0
CLTC 6428.0
PRDM14 6394.0
PSMB8 6380.0
CLDN7 6361.0
SEMA4D 6359.0
LHX4 6345.0
EFNB2 6329.0
RPL7A 6303.0
POU3F1 6262.0
CEBPA 6223.0
CDC42 6209.0
GPC1 6206.0
H3-3A 6189.0
SREBF1 6161.0
BMP4 6160.0
SRGAP2 6155.0
RARB 6147.0
ABLIM3 6129.0
RPS24 6102.0
GATA4 6093.0
PPARGC1A 6090.0
HOXC4 6081.0
GIT1 6045.0
CLTA 6001.0
GAB2 5996.0
NOG 5992.0
NR5A2 5991.0
LIPN 5973.0
KRTAP9-3 5919.0
H2BC6 5880.0
PIAS2 5865.0
SLIT3 5838.0
SOS1 5823.0
MED31 5807.0
CNTN1 5797.0
CHD9 5772.0
DHH 5764.0
PCK1 5753.0
RPL22L1 5729.0
NKX2-2 5712.0
FGF2 5707.0
TIAM1 5679.0
SDCBP 5661.0
THRAP3 5652.0
MEF2C 5633.0
INSM1 5618.0
MED10 5601.0
CDH4 5572.0
PSEN2 5569.0
RPS16 5553.0
MPZ 5522.0
MED13L 5514.0
KRTAP24-1 5477.0
LHX2 5472.0
KRTAP5-2 5467.0
FOXA1 5464.0
SPINK5 5451.0
DNM3 5441.0
MAFA 5426.0
RBBP4 5414.0
GATA2 5382.0
DPYSL3 5343.0
KRTAP10-4 5232.0
KRT36 5223.0
PFN2 5216.0
IHH 5201.0
MED18 5177.0
RPL28 5172.0
SEM1 5155.0
KCNQ2 5147.0
MAML3 5126.0
KALRN 5111.0
ADIRF 5104.0
KRTAP20-1 5074.0
CACNG2 5066.0
RPS9 5010.0
IVL 5005.0
PIK3R1 4998.0
GDNF 4978.0
RPS6KA4 4931.0
ADGRG6 4928.0
RPS25 4925.0
LCE3A 4908.0
AP2A1 4899.0
KRT17 4895.0
CACNA1I 4893.0
SLC2A2 4890.0
MMP2 4867.0
CAPNS1 4863.0
KRT78 4846.0
LIN28A 4827.0
KRTAP5-9 4818.0
LYN 4807.0
SPRR1A 4805.0
NCOR2 4797.0
ITGB1 4790.0
NCBP1 4784.0
GSPT1 4762.0
RBM8A 4753.0
GRB2 4749.0
KRT6B 4738.0
LCE3E 4718.0
PSEN1 4717.0
RPL39L 4698.0
PAK5 4685.0
KRTAP21-1 4659.0
TEAD1 4621.0
GRIN1 4616.0
LPL 4610.0
KRTAP4-5 4599.0
PSMB4 4596.0
DOK1 4538.0
PLIN1 4467.0
RRAS 4453.0
SHTN1 4433.0
DSC1 4411.0
HNF4A 4388.0
ARHGAP35 4379.0
MED21 4372.0
LGI3 4341.0
H3C2 4334.0
KRTAP19-5 4327.0
PDX1 4320.0
ROBO1 4253.0
RPL15 4228.0
AKAP5 4207.0
PSMD14 4205.0
ST8SIA2 4180.0
TEAD2 4171.0
SCN11A 4170.0
H2BC5 4154.0
PSMC1 4146.0
KCNQ3 4145.0
ITGA1 4143.0
ACVR2B 4141.0
GSK3B 4099.0
CDH1 4069.0
ABLIM1 4047.0
ST14 4015.0
RBX1 3985.0
LAMA2 3970.0
H2BC15 3952.0
CACNB4 3937.0
CTNNA2 3907.0
SOX2 3896.0
GAP43 3857.0
RPL13A 3845.5
DSG4 3830.0
RPL27 3820.0
LHX3 3794.0
PSMA7 3774.0
NODAL 3762.0
MAPK11 3751.0
CNTNAP1 3743.0
HELZ2 3691.0
UTRN 3680.0
PSMD4 3652.0
KRT19 3650.0
CACNB1 3648.0
HJV 3606.0
LCE2D 3589.0
DOK6 3580.0
FLI1 3567.0
KLK14 3557.0
POLR2C 3538.0
PSPN 3495.0
SLIT2 3477.0
PSMC5 3435.0
HSP90AB1 3410.0
PAK1 3361.0
PIK3CA 3346.0
TRPC4 3340.0
KLK13 3301.0
SMAD4 3279.0
POLR2I 3271.0
RPL11 3232.0
COL3A1 3229.0
GDF1 3212.0
SALL1 3209.0
MYH11 3157.0
ITGA5 3123.0
ZNF335 3113.0
ONECUT1 3103.0
LGI1 3084.0
MAPK12 3081.0
SCN8A 3061.0
CACNA1C 3041.0
CDH2 3040.0
MAML2 3033.0
SCN7A 3025.0
RPL4 3012.0
RPS20 3000.0
MED15 2995.0
NRTN 2972.0
KRTAP23-1 2952.0
PLXNC1 2918.0
RPL35 2913.0
RPL34 2908.0
MSI1 2857.0
ZFPM2 2845.0
CACNB2 2842.0
PSMD3 2823.0
GAB1 2794.0
SDC2 2781.0
ASH2L 2779.0
COL6A5 2775.0
RNPS1 2756.0
MAPK8 2729.0
ACTG1 2718.0
KRTAP4-2 2683.0
SCN1A 2659.0
SRC 2638.0
EZR 2623.0
COL9A2 2602.0
GFRA2 2595.0
H2BC17 2583.0
CACNA1D 2567.0
ELOC 2558.0
RGMA 2547.0
RPL18A 2540.0
H4C13 2526.0
GRB10 2523.0
ROBO3 2511.0
RPL35A 2508.0
LCE5A 2506.0
WNT3A 2499.0
CDKN1A 2479.0
UNC5D 2455.0
NR2F2 2429.0
SIAH1 2426.0
LCE1C 2425.0
SUZ12 2417.0
CTNNA1 2385.0
PSMB5 2383.0
TRIO 2327.0
EPHA5 2307.0
SCN4B 2300.0
PAXIP1 2259.0
DLL3 2238.0
COL4A1 2196.0
RPS21 2188.0
RPS12 2164.0
ITGA2 2112.0
RPS10 2082.0
SEMA3E 2069.0
H4C2 2031.0
MSGN1 2028.0
PDLIM7 1997.0
SPRR2G 1986.0
EPAS1 1984.0
ACTR3 1968.0
PPARA 1963.0
ROCK1 1951.0
PIK3CB 1937.0
DOK2 1919.0
RPS19 1918.0
IL6R 1910.0
MEF2A 1904.0
SPTBN5 1886.0
RHOC 1875.0
ANGPTL4 1839.0
AJUBA 1829.0
MED11 1822.0
PTPN11 1816.0
MYL6 1722.0
PRNP 1717.0
RPS7 1676.0
MYO10 1672.0
PKNOX1 1650.0
NOTCH1 1644.0
PSME4 1640.0
MED4 1635.0
COL2A1 1613.0
PSMD5 1604.0
DRAP1 1603.0
ADAM10 1586.0
MAP2K6 1531.0
PRKCA 1517.0
SPTBN1 1498.0
EPHA6 1491.0
PKP1 1480.0
H2AJ 1474.0
PSMB9 1422.0
FGF10 1421.0
KLF5 1420.0
STX1A 1418.0
CEBPB 1387.0
MEIS1 1381.0
MED29 1354.0
DOK4 1327.0
MAPK1 1304.0
EPHB1 1267.0
NRP2 1264.0
KAZN 1262.0
EPHA4 1252.0
COL4A3 1251.0
EGR2 1214.0
CXCL12 1209.0
NAB1 1197.0
ARPC4 1195.0
SLC2A4 1177.0
DLG4 1172.0
HMGCR 1165.0
KMT2A 1144.0
RPS6KA2 1136.0
EED 1128.0
HOXA1 1124.0
H2BC10 1117.0
PIK3R2 1089.0
CLASP1 1087.0
MED26 1077.0
MYB 1063.0
RPL30 1060.0
BOC 1015.0
SALL4 1012.0
SPRR3 992.0
TUBB4B 988.0
PRX 961.0
SEMA7A 956.0
SEMA6D 938.0
EFNA5 910.0
ST8SIA4 896.0
SPTB 891.0
EIF4G1 889.0
TREM2 879.0
SCN4A 856.0
EPHB2 831.0
KRT18 818.0
UPF2 809.0
RPL14 799.0
RPS2 787.0
EPHA10 773.0
DNM1 754.0
RPL7 753.0
MAPK13 743.0
NKX6-1 739.0
MAG 728.0
RPL23 697.0
KLK8 684.0
KRTAP19-3 674.0
AP2S1 663.0
MYO9B 638.0
COL4A2 624.0
NRCAM 616.0
ARHGEF11 596.0
TRPC7 553.0
KRTAP2-3 552.0
H4C5 481.0
KRT77 470.0
POLR2F 466.0
TCF12 459.0
MYH14 450.0
VAV3 447.0
FRS2 428.0
RPS6KA5 421.0
PSMA4 403.0
NCOA3 377.0
CACNA1G 366.0
INS 338.0
SRGAP1 328.0
RPL9 293.0
TFDP1 291.0
PAK6 287.0
KRTAP12-4 276.0
CDK2 273.0
POLR2K 272.0
FARP2 270.0
CUL2 238.0
NFASC 228.0
RPS18 225.0
RPS27A 210.0
H2AZ2 203.0
PTK2 195.0
NGEF 186.0
YAP1 138.0
MED1 127.0
SPTBN4 108.0
LEP 97.0
RPSA 85.0
H2BC9 36.5
H3C7 36.5
SPRR2F 3.0
RPL5 -25.0
RPS27L -42.0
ARHGEF12 -83.0
FOXA3 -93.0
H2BC11 -106.0
EBF1 -108.0
KRTAP1-5 -114.0
FOXF1 -115.0
CEBPD -137.0
PSMB2 -211.0
CSNK2B -255.0
CACNG8 -256.0
MED17 -307.0
PSMD11 -313.0
PBX1 -339.0
KRTAP5-3 -342.0
TCHH -383.0
POU3F2 -420.0
CASC3 -424.0
KRT35 -427.0
GRIN2B -451.0
PSME2 -465.0
COL5A1 -492.0
H4C11 -494.0
RPL36AL -512.5
TRPC6 -534.0
ACVR1B -558.0
DOCK1 -573.0
CDON -577.0
YES1 -582.0
MYC -588.0
DPYSL5 -594.0
FOXA2 -617.0
SCN1B -619.0
TRPC1 -626.0
NCAN -630.0
PSMC3 -685.0
KRTAP1-1 -696.0
RPL31 -712.0
VAV2 -718.0
PSMB6 -723.0
UBB -760.0
DEK -782.0
RPLP0 -801.0
EVPL -803.0
NTN1 -826.0
UNC5C -838.0
UNC5A -882.0
CSNK2A2 -889.0
RPLP2 -896.0
MBP -903.0
ROBO2 -905.0
ACVR1C -907.0
DSCAM -923.0
MMP9 -947.0
RPL21 -953.0
RPL26 -958.0
DPPA4 -981.0
LCE2B -991.0
COL9A1 -1000.0
TUBA1B -1007.0
SLIT1 -1018.0
GFRA1 -1023.0
H3C8 -1035.0
RPS8 -1044.0
CDK19 -1048.0
OCLN -1049.0
H2AC4 -1132.0
LIMK1 -1145.0
MEF2B -1146.0
MYL12A -1147.0
ARPC3 -1148.0
BNIP2 -1165.0
COL6A6 -1171.0
KRT38 -1185.0
DCC -1198.0
ALCAM -1204.0
H4C16 -1250.0
HOXD1 -1252.0
RUNX1 -1269.0
AKT3 -1295.0
HOXB1 -1305.0
FOXP1 -1365.0
FGF9 -1373.0
PML -1375.0
PSMB1 -1423.0
ANK3 -1433.0
NELL2 -1472.0
SOX9 -1522.0
TBX6 -1576.0
DSC2 -1623.0
RBPJ -1631.0
PPARG -1645.0
JUN -1705.0
PRKACG -1720.0
MED16 -1723.0
H2BC12 -1743.0
PAX4 -1746.0
KRT37 -1793.0
RHOA -1807.0
ARHGEF28 -1809.0
KRT15 -1836.0
DLL1 -1838.0
KRTAP12-3 -1933.0
RPL18 -1942.0
TFDP2 -1943.0
DLG1 -1956.0
KRTAP13-1 -1958.0
KRTAP10-8 -1969.0
LGI4 -1996.0
ADAM22 -2008.0
EPHA1 -2012.0
ABLIM2 -2013.0
PSMA3 -2026.0
APH1B -2030.0
CREBBP -2076.0
PRKCQ -2103.0
KRT10 -2126.0
RAC1 -2129.0
H4C12 -2167.0
SREBF2 -2175.0
ZSCAN10 -2197.0
KMT2C -2208.0
KRT6C -2234.0
MESP2 -2275.0
CXCR4 -2279.0
MED22 -2281.0
PLXNA1 -2282.0
KRT6A -2310.0
ANK1 -2316.0
CDK4 -2328.0
MED27 -2341.0
KRTAP10-11 -2375.0
TUBB4A -2409.0
MED13 -2419.0
KRT9 -2420.0
KRTAP13-4 -2422.0
TCF4 -2426.0
KRT31 -2441.0
MAPK14 -2455.0
PIK3R3 -2476.0
RPS27 -2513.0
KRTAP10-5 -2520.0
MED25 -2525.0
ITGA2B -2543.0
TBL1XR1 -2551.0
CNOT6 -2554.0
DSP -2574.0
ARHGAP39 -2595.0
SMAD3 -2599.0
ISL1 -2605.0
KRTAP2-4 -2613.0
H4C6 -2615.0
DNM2 -2651.0
PSMB10 -2660.0
TAL1 -2677.0
HDAC3 -2692.0
MED6 -2699.0
POLR2H -2702.0
NFKB1 -2712.0
KLK5 -2759.0
ANK2 -2783.0
STAT3 -2790.0
NR5A1 -2791.0
EPHA8 -2817.0
CNOT9 -2819.0
PKP3 -2841.0
ABL2 -2846.0
ABL1 -2852.0
TUBA1A -2863.0
E2F1 -2893.0
FOXO1 -2896.0
CACNA1S -2924.0
LAMA1 -2935.0
SCN2A -2937.0
NCOA2 -2942.0
GCK -2967.0
WWTR1 -2968.0
LDB1 -2984.0
TUBA1C -2997.0
RPL13 -3022.0
CDX2 -3090.0
TSC22D1 -3116.0
HOXA3 -3170.0
COL5A2 -3182.0
RET -3224.0
CACNG4 -3258.0
MAGOHB -3261.0
TUBA3C -3266.0
CDSN -3286.0
ADAM23 -3292.0
HSPA8 -3316.0
SPAG9 -3330.0
ZNF638 -3346.0
NCSTN -3348.0
EOMES -3390.0
CTNNB1 -3397.0
KRT28 -3406.0
CCND3 -3416.0
TUBB2A -3433.0
CER1 -3434.0
ARPC2 -3442.0
PKP4 -3498.0
MYH10 -3520.0
MED8 -3534.0
PIP5K1C -3537.0
TRPC3 -3551.0
SHC3 -3556.0
KRT25 -3643.0
RPS11 -3646.0
NTN4 -3672.0
ROCK2 -3673.0
EFNA3 -3715.0
ITGB3 -3725.0
NCK1 -3736.0
UBC -3749.0
MED20 -3764.0
KRTAP19-2 -3773.0
SRGAP3 -3783.0
H4C3 -3847.0
RPS15A -3879.0
NCBP2 -3923.0
MAPK7 -3992.0
HES1 -4032.0
FAU -4041.0
PSMD6 -4053.0
PPP3CB -4085.0
HOXB4 -4100.0
MYOD1 -4106.0
FAM120B -4123.0
SHH -4141.0
PRKACA -4231.0
ITSN1 -4234.0
PSMA5 -4249.0
FYN -4258.0
POLR2J -4267.0
RPS3 -4268.0
RELN -4276.0
RPL41 -4291.0
AP2A2 -4338.0
ZNF467 -4345.0
ITGA9 -4364.0
KRTAP9-9 -4437.0
COL6A2 -4445.0
KRAS -4450.0
KLK12 -4532.0
MAP2K2 -4538.0
RGMB -4545.0
ELOB -4550.0
HSP90AA1 -4552.0
RARG -4583.0
CD36 -4590.0
PIK3CD -4597.0
RPS6 -4622.0
PSMD8 -4639.0
KRTAP10-7 -4644.0
PSMD7 -4693.0
PSMA8 -4702.0
ENAH -4741.0
H3-3B -4811.0
PTPRA -4828.0
CELA2A -4858.0
EZH2 -4861.0
SEMA3A -4866.0
TNF -4900.0
RPL6 -4911.0
LCE1B -4936.0
RPS3A -4938.0
LAMC1 -4954.0
DSC3 -4962.0
MED19 -4970.0
CRMP1 -4978.0
CARM1 -5002.0
H4C9 -5033.0
FOXD3 -5047.0
KRTAP19-6 -5063.0
PSMC4 -5080.0
CLTB -5089.0
POLR2L -5100.0
PAK2 -5107.0
PLXNB1 -5139.0
NCOA6 -5143.0
RBBP5 -5151.0
DSG1 -5168.0
AP2B1 -5173.0
FABP4 -5181.0
PTPRC -5207.0
RPS26 -5257.0
LEF1 -5292.0
CAP2 -5333.0
SEMA6A -5338.0
CREB1 -5377.0
POLR2E -5379.0
NR6A1 -5389.0
MET -5396.0
H2BC1 -5406.0
H4C4 -5408.0
CBFB -5420.0
DAND5 -5430.0
CHL1 -5436.0
KRT86 -5480.0
RHOB -5521.0
KRTAP5-11 -5524.0
CNTN2 -5550.0
DAG1 -5610.0
RAP1GAP -5620.0
KRT81 -5631.0
KRTAP4-3 -5690.0
MAP2K1 -5708.0
EFNA1 -5728.0
ITGAV -5756.0
TLN1 -5759.0
SCN3B -5779.0
TUBB2B -5782.0
HIF3A -5789.0
KAT2B -5792.0
ARHGEF7 -5798.0
PAGR1 -5823.0
CTCF -5868.0
COL6A1 -5884.0
RPL26L1 -5886.0
CAPN1 -5964.0
PCSK6 -6003.0
AGAP2 -6029.0
ETF1 -6036.0
CLASP2 -6038.0
KRT27 -6039.0
NUMB -6059.0
CACNA1H -6065.0
RPS29 -6101.0
NCOR1 -6111.0
ERBB2 -6120.0
CDK5 -6162.0
CFL1 -6192.0
PSMC6 -6194.0
LIPJ -6284.0
DPYSL4 -6341.0
LAMB1 -6347.0
PSMD9 -6362.0
KRTAP3-1 -6368.0
PSENEN -6381.0
ARPC1B -6450.0
KRTAP10-10 -6454.0
KRT20 -6517.0
MED30 -6521.0
CACNB3 -6537.0
MAPK3 -6553.0
KRTAP4-1 -6600.0
KRT73 -6788.0
UPF3A -6804.0
KRT83 -6823.0
FOXO3 -6836.0
KRTAP10-1 -6872.0
LIPM -6885.0
IRS2 -6927.0
KRTAP12-1 -7065.0
KAT2A -7092.0
CCNC -7100.0
SOX10 -7135.0
PTGDS -7163.0
POLR2B -7177.0
PLCG1 -7205.0
TCF3 -7206.0
FLG -7244.0
RPL19 -7259.0
KRT82 -7298.0
SEMA5A -7380.0
SCN10A -7414.0
EP300 -7432.0
MYH9 -7450.0
H3C11 -7455.0
NAB2 -7464.0
SOS2 -7482.0
H2BC21 -7485.0
WDR5 -7515.0
JUP -7518.0
MED23 -7531.0
PSME3 -7537.0
RPS23 -7595.0
KRTAP17-1 -7618.0
CACNG3 -7626.0
KRTAP20-2 -7633.0
TUBAL3 -7648.0
AKT1 -7654.0
SPRR2D -7679.0
H2BC8 -7687.0
PSMD1 -7718.0
H2AX -7754.0
H4C1 -7768.0
CYP51A1 -7775.0
EPHB4 -7804.0
TEAD4 -7843.0
MED24 -7859.0
RPL24 -7908.0
RFX6 -7911.0
WASL -7917.0
RDX -7974.0
EPHA3 -7988.0
H2AC8 -8007.0
HRAS -8010.0
EFNA4 -8034.0
POU5F1 -8054.0
KRT40 -8069.0
PABPC1 -8095.0
AP2M1 -8109.0
KRTAP5-6 -8119.0
SNW1 -8150.0
MED28 -8205.0
H2BC14 -8236.0
ARPC1A -8248.0
NCOA1 -8254.0
H3C1 -8260.0
ITGA10 -8287.0
TRIM33 -8297.0
COL6A3 -8308.0
GFRA4 -8447.0
RPS5 -8455.0
HOXA4 -8471.0
ARPC5 -8477.0
NCK2 -8483.0
HOXB3 -8511.0
AGRN -8546.0
POLR2A -8553.0
KRTAP27-1 -8592.0
FGFR1 -8617.0
KRTAP15-1 -8643.0
TGFB1 -8682.0
PPL -8698.0
KRTAP6-1 -8700.0
YY1 -8726.0
KRTAP16-1 -8729.0
PSMD12 -8730.0
CLTCL1 -8736.0
MYOG -8739.0
EVL -8755.0
RPTN -8759.0
PCGF2 -8767.0
RELA -8787.0
KRTAP3-2 -8958.0
EIF4A3 -8959.0
KRTAP19-8 -9011.0
H2AC18 -9031.5
H2AC19 -9031.5
CDK8 -9038.0
TGS1 -9058.0
EPHB6 -9082.0
KRTAP1-3 -9093.0
PSMD13 -9136.0
PKP2 -9139.0
SPTBN2 -9143.0
ADIPOQ -9172.0
PSMF1 -9180.0
KRTAP12-2 -9184.0
SPRR2A -9202.0
RPL37A -9220.0
APH1A -9231.0
LELP1 -9233.0
RANBP9 -9240.0
LCE2C -9241.0
PAK4 -9310.0
USP33 -9333.0
PRSS8 -9337.0
SMARCA4 -9405.0
SCN5A -9414.0
RPS15 -9442.0
NANOG -9536.0
KRTAP21-3 -9560.0
RPS14 -9594.0
LCE1E -9638.0
H3C4 -9701.0
KRTAP6-3 -9714.0
RPL3L -9803.0
PITPNA -9811.0
PKLR -9894.0
KRT8 -9916.0
KRTAP10-12 -9927.0
KRTAP25-1 -9948.0
AKT2 -9950.0
H2AC14 -9995.0
CDK5R1 -10016.0
KRTAP19-7 -10024.0
MED9 -10026.0
HNF1A -10037.0
KRTAP9-1 -10042.0
KRT75 -10057.0
H2AC20 -10070.0
SPTAN1 -10082.0
TCF7 -10093.0
PSMB11 -10116.0
TUBA3D -10142.0
H2AC7 -10188.5
H2BC7 -10188.5
KRT39 -10219.0
RPL22 -10230.0
KRTAP19-4 -10247.0
PSME1 -10255.0
H2BC26 -10276.0
KRTAP9-4 -10285.0
KRTAP4-7 -10293.0
KRT24 -10336.0
RPL10L -10366.0
KRTAP2-2 -10371.0
KMT2D -10466.0
FURIN -10505.0
LIPK -10531.0
ZSWIM8 -10584.0
KRTAP4-6 -10670.0
KIF4B -10689.0
H3C6 -10696.0
TGM1 -10729.0
H3C3 -10752.0
KRTAP5-8 -10761.0
PSMD2 -10774.0
KRT1 -10820.0
KRT26 -10864.0
KRTAP5-1 -10881.0
KRTAP2-1 -10962.0
KRTAP3-3 -11066.0
H2BC3 -11072.0
KRTAP4-8 -11090.0
KRTAP10-2 -11112.0
KRTAP5-7 -11203.0
KRTAP10-9 -11210.0


REACTOME_CILIUM_ASSEMBLY

REACTOME_CILIUM_ASSEMBLY
902
set REACTOME_CILIUM_ASSEMBLY
setSize 190
pANOVA 0.00512
s.dist -0.118
p.adjustANOVA 0.331



Top enriched genes

Top 20 genes
GeneID Gene Rank
CEP89 -10204
TUBA3D -10142
KIF24 -9971
EXOC3 -9845
CNGA4 -9757
MAPRE1 -9576
DYNLL2 -9535
UNC119B -9359
NPHP4 -9129
CEP72 -8985
PCNT -8980
TMEM67 -8973
SSTR3 -8941
CEP41 -8908
KIF3A -8903
IFT27 -8821
INPP5E -8811
CYS1 -8707
NEK2 -8647
CEP83 -8520

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CEP89 -10204
TUBA3D -10142
KIF24 -9971
EXOC3 -9845
CNGA4 -9757
MAPRE1 -9576
DYNLL2 -9535
UNC119B -9359
NPHP4 -9129
CEP72 -8985
PCNT -8980
TMEM67 -8973
SSTR3 -8941
CEP41 -8908
KIF3A -8903
IFT27 -8821
INPP5E -8811
CYS1 -8707
NEK2 -8647
CEP83 -8520
CSNK1D -8377
IFT22 -8264
CEP57 -8242
HAUS5 -8108
PKD1 -8043
KIF3B -8017
CEP192 -7901
IFT140 -7753
KIFAP3 -7736
DYNC1I2 -7729
EXOC2 -7653
TUBAL3 -7648
CCP110 -7536
DYNC1H1 -7456
WDR19 -7215
DYNLRB2 -7020
PLK4 -6912
PAFAH1B1 -6772
IFT172 -6541
CEP97 -6424
BBS1 -6324
BBS4 -6291
SSNA1 -6279
HAUS8 -6193
NDE1 -6187
CEP76 -6152
YWHAE -5897
EXOC5 -5889
EXOC1 -5866
TUBB2B -5782
CEP63 -5505
TCTN1 -5471
DYNC2I2 -5273
CNTRL -5234
DYNLT5 -4964
CEP43 -4867
NPHP1 -4726
HSP90AA1 -4552
CCT2 -4530
BBIP1 -4499
ACTR1A -4420
TCTN2 -4380
ODF2 -4375
PCM1 -4344
PRKACA -4231
RAB8A -4154
ARL13B -4135
HAUS2 -4128
KIF17 -4112
EXOC4 -4014
DYNLT2 -3990
SCLT1 -3942
DYNLT2B -3934
CEP70 -3812
CCT4 -3748
IFT88 -3626
IFT52 -3570
LZTFL1 -3542
TTC21B -3450
TUBB2A -3433
IQCB1 -3410
CEP250 -3379
CCT5 -3365
CEP152 -3329
TUBA3C -3266
IFT122 -3177
TUBA1C -2997
DYNC2I1 -2978
CENPJ -2940
KIF3C -2927
CSNK1E -2909
TUBA1A -2863
PDE6D -2765
BBS7 -2594
IFT57 -2480
TUBB4A -2409
IFT20 -2394
GBF1 -2311
MARK4 -2309
CEP131 -2181
SFI1 -2028
CEP78 -2019
TTBK2 -1939
EXOC8 -1707
CEP162 -1646
RAB11A -1584
EXOC7 -1476
NEDD1 -1360
RAB3IP -1327
IFT46 -1133
TUBA1B -1007
HAUS3 -886
CC2D2A -805
CEP164 -710
RAB11FIP3 -642
ALMS1 -387
CDK1 -191
DYNLL1 -62
TNPO1 -60
CKAP5 -58
TTC8 16
FBF1 66
YWHAG 239
BBS2 255
PPP2R1A 545
CLUAP1 906
HAUS4 922
TUBB4B 988
CLASP1 1087
TUBB 1258
SMO 1343
CDK5RAP2 1425
BBS9 1522
B9D2 1534
IFT80 1595
DCTN3 1620
RHO 1712
TUBG1 1796
CCT3 1902
CCT8 1966
ASAP1 2222
ARL6 2444
C2CD3 2469
NPHP3 2792
IFT74 2924
PLK1 3043
PKD2 3137
NINL 3228
PRKAR2B 3261
ARL3 3337
CNGB1 3383
CEP135 3662
DCTN1 3760
EXOC6 3786
WDR35 3905
IFT81 3908
IFT43 4017
B9D1 4024
HAUS1 4455
AHI1 4567
TCP1 4787
SDCCAG8 4878
BBS5 5196
DYNC2H1 5231
AKAP9 5256
CEP290 5498
MKKS 5549
TRAF3IP1 5622
DYNC2LI1 5696
TRIP11 5810
HAUS6 5843
DYNLRB1 6100
TUBA8 6563
BBS12 7139
ATAT1 7317
TUBB3 7518
DCTN2 7748
TUBA4B 7781
TCTN3 8062
TUBB1 8143
TUBA4A 8277
RPGRIP1L 8694
BBS10 8729
ARF4 9034
TUBB6 9036
MCHR1 9331
MKS1 9397
TMEM216 9425
TUBA3E 9950
TUBB8 10294


REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS

REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS
595
set REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS
setSize 93
pANOVA 0.00518
s.dist 0.168
p.adjustANOVA 0.331



Top enriched genes

Top 20 genes
GeneID Gene Rank
PTH2 10450
GNG11 10395
PTCH2 10024
IAPP 9901
GHRHR 9498
WNT1 8966
ADGRE1 8850
GNB5 8214
PTHLH 8025
UCN3 7831
GNG12 7733
ADCYAP1R1 7644
RAMP2 7347
GNAS 7253
FZD2 7150
CALCR 7072
GNG8 6938
ADGRE3 6925
WNT2B 6907
WNT10B 6840

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PTH2 10450
GNG11 10395
PTCH2 10024
IAPP 9901
GHRHR 9498
WNT1 8966
ADGRE1 8850
GNB5 8214
PTHLH 8025
UCN3 7831
GNG12 7733
ADCYAP1R1 7644
RAMP2 7347
GNAS 7253
FZD2 7150
CALCR 7072
GNG8 6938
ADGRE3 6925
WNT2B 6907
WNT10B 6840
WNT4 6810
FZD5 6795
GIP 6560
CRHR1 6335
ADM2 6299
FZD4 6057
DHH 5764
WNT7A 5612
CALCA 5303
IHH 5201
WNT6 5007
UCN 4814
GNG13 4682
WNT8A 4088
RAMP1 3883
SCT 3647
GHRH 3607
VIPR1 3429
WNT5A 3360
WNT8B 3238
PTH1R 3074
CRH 2974
CALCB 2671
FZD1 2582
WNT3A 2499
FZD9 2117
GCG 2002
ADCYAP1 1873
ADM 1391
VIP 1345
SMO 1343
PTH2R 1270
WNT9A 1016
CALCRL 821
CRHBP 562
FZD8 561
GIPR -396
WNT16 -516
FZD10 -542
GNG2 -702
GNG5 -891
VIPR2 -1033
GNB3 -1123
GNG4 -1138
GLP1R -1140
RAMP3 -2074
WNT11 -2200
UCN2 -2384
WNT10A -2671
WNT7B -2755
GNGT2 -3018
ADGRE2 -3319
WNT9B -3327
GNG7 -3536
WNT2 -3892
GNB2 -4115
SHH -4141
GNG10 -4182
CRHR2 -4228
GNG3 -4555
GNB1 -5364
WNT3 -5382
CD55 -5455
PTCH1 -5478
ADGRE5 -5547
SCTR -5596
FZD3 -6701
GNB4 -7354
PTH -7779
GLP2R -8041
GNGT1 -8140
FZD6 -8718
FZD7 -9142


REACTOME_PHASE_3_RAPID_REPOLARISATION

REACTOME_PHASE_3_RAPID_REPOLARISATION
882
set REACTOME_PHASE_3_RAPID_REPOLARISATION
setSize 8
pANOVA 0.00524
s.dist 0.57
p.adjustANOVA 0.331



Top enriched genes

Top 20 genes
GeneID Gene Rank
KCNE1 10329
KCNE3 10289
KCNE2 10013
KCNA5 8553
AKAP9 5256
KCNH2 4345
KCNE4 -340
KCNQ1 -431

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
KCNE1 10329
KCNE3 10289
KCNE2 10013
KCNA5 8553
AKAP9 5256
KCNH2 4345
KCNE4 -340
KCNQ1 -431


REACTOME_G_ALPHA_S_SIGNALLING_EVENTS

REACTOME_G_ALPHA_S_SIGNALLING_EVENTS
705
set REACTOME_G_ALPHA_S_SIGNALLING_EVENTS
setSize 155
pANOVA 0.00545
s.dist 0.129
p.adjustANOVA 0.331



Top enriched genes

Top 20 genes
GeneID Gene Rank
PTH2 10450
GNG11 10395
MC5R 10281
DRD5 10142
GPHB5 10083
IAPP 9901
FSHB 9874
GHRHR 9498
GRK2 9489
CYSLTR2 9245
LHCGR 8838
PDE3B 8806
FSHR 8764
GNAI2 8546
AVP 8433
PRKAR2A 8317
GNB5 8214
RLN2 8043
PTHLH 8025
GNG12 7733

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PTH2 10450
GNG11 10395
MC5R 10281
DRD5 10142
GPHB5 10083
IAPP 9901
FSHB 9874
GHRHR 9498
GRK2 9489
CYSLTR2 9245
LHCGR 8838
PDE3B 8806
FSHR 8764
GNAI2 8546
AVP 8433
PRKAR2A 8317
GNB5 8214
RLN2 8043
PTHLH 8025
GNG12 7733
SHC1 7700
ADCYAP1R1 7644
TAAR6 7553
ADCY8 7533
HTR6 7496
RAMP2 7347
GNAS 7253
POMC 7181
CALCR 7072
MC2R 7071
ADRB1 7026
GNG8 6938
GPBAR1 6814
PRKACB 6694
GIP 6560
GPR150 6499
PTGER4 6466
CRHR1 6335
ADM2 6299
GPR84 6200
PDE2A 6140
PDE10A 6117
P2RY11 6104
RLN3 5954
TSHB 5734
PDE3A 5699
ADCY4 5698
DRD1 5577
HTR7 5555
ARRB1 5403
CALCA 5303
PDE4D 5290
ITGB1 4790
GNG13 4682
ADORA2B 4641
RXFP1 4613
RXFP2 4606
ADRB2 4192
RAMP1 3883
SCT 3647
GHRH 3607
GPR39 3533
PRKAR1A 3464
VIPR1 3429
GNAI1 3381
PRKAR2B 3261
ITGA5 3123
PTH1R 3074
PTGER2 2987
CRH 2974
CALCB 2671
SRC 2638
GRK5 2304
GCG 2002
ADCYAP1 1873
PDE1A 1820
ADCY1 1793
NPS 1761
ADCY6 1641
ADCY2 1409
ADM 1391
VIP 1345
PDE1B 1342
PTH2R 1270
MC1R 1208
ADCY5 1097
CALCRL 821
GRK3 784
PDE8A 571
PTGDR 124
FN1 29
PDE4C -298
GIPR -396
TSHR -615
ADCY9 -632
GNG2 -702
HRH2 -720
GPR176 -840
GNG5 -891
GPR27 -942
PDE4A -964
VIPR2 -1033
GNB3 -1123
GNG4 -1138
GLP1R -1140
GNAT3 -1350
LHB -1370
CGA -1525
PRKACG -1720
MC3R -1725
GNAI3 -1954
RAMP3 -2074
PDE11A -2484
GNGT2 -3018
PDE8B -3296
PRKAR1B -3310
GNG7 -3536
GPR83 -3691
PDE7A -3770
ARRB2 -3809
GNB2 -4115
GNG10 -4182
CRHR2 -4228
PRKACA -4231
GNG3 -4555
GNAZ -4767
HTR4 -5065
MC4R -5099
NPSR1 -5120
GNB1 -5364
ADRB3 -5421
SCTR -5596
TAAR1 -6126
GRK6 -6130
PDE7B -6567
TAAR5 -6602
GPER1 -7252
GNB4 -7354
PTH -7779
GLP2R -8041
GNGT1 -8140
ADCY3 -8198
INSL3 -8210
GPR25 -8900
ADCY7 -9295
GPR20 -9719
TAAR9 -9736
TAAR2 -9761
ADORA2A -10485
GPR32 -10507
GPR15 -10727
GPR45 -10904
PTGIR -11030
TAAR8 -11075
GPHA2 -11256


REACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION

REACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION
1279
set REACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION
setSize 90
pANOVA 0.00589
s.dist -0.168
p.adjustANOVA 0.342



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC3 -11072.0
KMT2B -11022.0
H3C3 -10752.0
H3C6 -10696.0
KMT2D -10466.0
H2BC26 -10276.0
H2AC7 -10188.5
H2BC7 -10188.5
H2AC20 -10070.0
GP1BA -10041.0
H2AC14 -9995.0
H3C4 -9701.0
H2AC18 -9031.5
H2AC19 -9031.5
H3C1 -8260.0
H2BC14 -8236.0
H2AC8 -8007.0
SIN3B -7876.0
H4C1 -7768.0
H2AX -7754.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC3 -11072.0
KMT2B -11022.0
H3C3 -10752.0
H3C6 -10696.0
KMT2D -10466.0
H2BC26 -10276.0
H2AC7 -10188.5
H2BC7 -10188.5
H2AC20 -10070.0
GP1BA -10041.0
H2AC14 -9995.0
H3C4 -9701.0
H2AC18 -9031.5
H2AC19 -9031.5
H3C1 -8260.0
H2BC14 -8236.0
H2AC8 -8007.0
SIN3B -7876.0
H4C1 -7768.0
H2AX -7754.0
PRMT6 -7699.0
H2BC8 -7687.0
WDR5 -7515.0
H2BC21 -7485.0
H3C11 -7455.0
EP300 -7432.0
KMT2E -7079.0
HDAC1 -6364.0
TNRC6A -6172.0
KAT2B -5792.0
CBFB -5420.0
H4C4 -5408.0
H2BC1 -5406.0
RBBP5 -5151.0
SETD1A -5060.0
TNRC6B -5055.0
H4C9 -5033.0
H3-3B -4811.0
ZFPM1 -4379.0
H4C3 -3847.0
PRMT1 -3846.0
H4C6 -2615.0
THBS1 -2553.0
ITGA2B -2543.0
KMT2C -2208.0
H4C12 -2167.0
PRKCQ -2103.0
H2BC12 -1743.0
MOV10 -1363.0
RUNX1 -1269.0
H4C16 -1250.0
AGO4 -1170.0
H2AC4 -1132.0
H3C8 -1035.0
NR4A3 -963.0
H4C11 -494.0
H2BC11 -106.0
H2BC9 36.5
H3C7 36.5
H2AZ2 203.0
H4C5 481.0
H2BC10 1117.0
KMT2A 1144.0
TNRC6C 1179.0
SIN3A 1355.0
H2AJ 1474.0
SETD1B 1562.0
H4C2 2031.0
DPY30 2505.0
H4C13 2526.0
H2BC17 2583.0
AGO3 2772.0
ASH2L 2779.0
H2BC15 3952.0
H2BC5 4154.0
H3C2 4334.0
PF4 4678.0
H2BC6 5880.0
MIR27A 5889.0
H3-3A 6189.0
H4C8 6856.0
H3C10 8230.0
H2AZ1 8703.0
H2BC13 8750.0
NFE2 9007.0
H2AC6 9114.0
MYL9 9523.0
H2BC4 9890.0
AGO1 10069.0
H3C12 10509.0


REACTOME_DNA_DOUBLE_STRAND_BREAK_REPAIR

REACTOME_DNA_DOUBLE_STRAND_BREAK_REPAIR
1008
set REACTOME_DNA_DOUBLE_STRAND_BREAK_REPAIR
setSize 162
pANOVA 0.00632
s.dist -0.124
p.adjustANOVA 0.342



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC3 -11072.0
PIAS4 -10499.0
H2BC26 -10276.0
UBE2V2 -10249.0
H2BC7 -10188.5
POLD2 -9835.0
H3-4 -9817.0
CLSPN -9799.0
RNF168 -9652.0
HERC2 -9585.0
RNF4 -9539.0
SUMO2 -9534.0
SIRT6 -9353.0
XRCC6 -9311.0
POLD1 -9280.0
RMI2 -8964.0
DNA2 -8554.0
PARP1 -8387.0
RNF8 -8282.0
H2BC14 -8236.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC3 -11072.0
PIAS4 -10499.0
H2BC26 -10276.0
UBE2V2 -10249.0
H2BC7 -10188.5
POLD2 -9835.0
H3-4 -9817.0
CLSPN -9799.0
RNF168 -9652.0
HERC2 -9585.0
RNF4 -9539.0
SUMO2 -9534.0
SIRT6 -9353.0
XRCC6 -9311.0
POLD1 -9280.0
RMI2 -8964.0
DNA2 -8554.0
PARP1 -8387.0
RNF8 -8282.0
H2BC14 -8236.0
UBE2I -8199.0
RAD52 -7959.0
APBB1 -7928.0
EYA2 -7899.0
POLD3 -7854.0
PPP5C -7850.0
H4C1 -7768.0
H2AX -7754.0
H2BC8 -7687.0
H2BC21 -7485.0
XRCC2 -7347.0
RHNO1 -6956.0
NSD2 -6909.0
POLE -6750.0
TIMELESS -6646.0
RAD9A -6607.0
ERCC4 -6548.0
ABRAXAS1 -6006.0
RPA1 -5995.0
POLH -5972.0
XRCC1 -5898.0
KDM4B -5696.0
MUS81 -5590.0
KAT5 -5557.0
RAD51 -5528.0
TP53 -5513.0
H4C4 -5408.0
H2BC1 -5406.0
NBN -5357.0
MDC1 -5348.0
DCLRE1C -5204.0
H4C9 -5033.0
UIMC1 -4967.0
TIPIN -4942.0
RAD51D -4806.0
TDP1 -4696.0
LIG3 -4480.0
POLE3 -3924.0
H4C3 -3847.0
POLM -3750.0
UBC -3749.0
SUMO1 -3709.0
KDM4A -3560.0
TOPBP1 -3164.0
RAD51C -3047.0
ABL1 -2852.0
ATM -2840.0
PCNA -2763.0
H4C6 -2615.0
TOP3A -2386.0
RPA2 -2350.0
BAP1 -2307.0
CHEK1 -2287.0
H4C12 -2167.0
EYA1 -1962.0
NHEJ1 -1953.0
KPNA2 -1894.0
RFC2 -1857.0
FEN1 -1752.0
H2BC12 -1743.0
HUS1 -1475.0
POLK -1351.0
POLQ -1281.0
H4C16 -1250.0
EME2 -1224.0
RPA3 -1106.0
ATR -1075.0
PALB2 -890.0
RTEL1 -797.0
UBB -760.0
POLE2 -740.0
EXO1 -533.0
H4C11 -494.0
RAD9B -363.0
TDP2 -240.0
PARP2 -209.0
ATRIP -199.0
H2BC11 -106.0
H2BC9 36.5
MRE11 41.0
RPS27A 210.0
BRCA1 231.0
CDK2 273.0
XRCC5 416.0
H4C5 481.0
RAD51B 496.0
BARD1 611.0
RFC4 617.0
POLL 676.0
RFC3 775.0
PRKDC 786.0
H2BC10 1117.0
RFC5 1138.0
POLD4 1139.0
EYA4 1501.0
BAZ1B 1529.0
H4C2 2031.0
XRCC4 2096.0
RAD50 2206.0
PAXIP1 2259.0
RAD17 2339.0
POLE4 2477.0
SMARCA5 2520.0
H4C13 2526.0
RIF1 2527.0
H2BC17 2583.0
WRN 2634.0
MAPK8 2729.0
RAD51AP1 2923.0
GEN1 3323.0
BABAM2 3586.0
SLX4 3596.0
RFC1 3816.0
LIG4 3868.0
TP53BP1 3925.0
CHEK2 3950.0
H2BC15 3952.0
EME1 4012.0
PPP4C 4091.0
H2BC5 4154.0
RAD1 4287.0
BLM 4939.0
SEM1 5155.0
XRCC3 5596.0
CCNA2 5812.0
H2BC6 5880.0
RMI1 5934.0
SPIDR 6014.0
UBXN1 6538.0
RBBP8 6725.0
H4C8 6856.0
BABAM1 6905.0
ERCC1 7111.0
EYA3 7131.0
BRCA2 7348.0
UBA52 7581.0
PPP4R2 7704.0
BRIP1 7863.0
UBE2N 8089.0
H2BC13 8750.0
CCNA1 8842.0
H2BC4 9890.0


REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS

REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS
416
set REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS
setSize 13
pANOVA 0.00637
s.dist 0.437
p.adjustANOVA 0.342



Top enriched genes

Top 20 genes
GeneID Gene Rank
CGB8 10624
INHBE 10452
INHBC 10355
INHBA 10349
FSHB 9874
POMC 7181
TSHB 5734
PCSK1 5046
INHA 1750
INHBB 1645
LHB -1370
CGA -1525
CGB5 -11135

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CGB8 10624
INHBE 10452
INHBC 10355
INHBA 10349
FSHB 9874
POMC 7181
TSHB 5734
PCSK1 5046
INHA 1750
INHBB 1645
LHB -1370
CGA -1525
CGB5 -11135


REACTOME_TELOMERE_MAINTENANCE

REACTOME_TELOMERE_MAINTENANCE
153
set REACTOME_TELOMERE_MAINTENANCE
setSize 106
pANOVA 0.00676
s.dist -0.152
p.adjustANOVA 0.342



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC3 -11072.0
H2BC26 -10276.0
H2AC7 -10188.5
H2BC7 -10188.5
H2AC20 -10070.0
H2AC14 -9995.0
POLD2 -9835.0
H3-4 -9817.0
POLD1 -9280.0
H2AC18 -9031.5
H2AC19 -9031.5
TERF1 -8662.0
TERT -8587.0
LIG1 -8555.0
DNA2 -8554.0
POLR2A -8553.0
CHTF8 -8508.0
H2BC14 -8236.0
SHQ1 -8050.0
H2AC8 -8007.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC3 -11072.0
H2BC26 -10276.0
H2AC7 -10188.5
H2BC7 -10188.5
H2AC20 -10070.0
H2AC14 -9995.0
POLD2 -9835.0
H3-4 -9817.0
POLD1 -9280.0
H2AC18 -9031.5
H2AC19 -9031.5
TERF1 -8662.0
TERT -8587.0
LIG1 -8555.0
DNA2 -8554.0
POLR2A -8553.0
CHTF8 -8508.0
H2BC14 -8236.0
SHQ1 -8050.0
H2AC8 -8007.0
POLD3 -7854.0
H4C1 -7768.0
H2AX -7754.0
H2BC8 -7687.0
RUVBL1 -7570.0
H2BC21 -7485.0
ACD -7311.5
POLR2B -7177.0
TERF2 -6723.0
RPA1 -5995.0
H4C4 -5408.0
H2BC1 -5406.0
ANKRD28 -5401.0
POLR2E -5379.0
POLR2L -5100.0
H4C9 -5033.0
H3-3B -4811.0
CHTF18 -4621.0
PRIM1 -4339.0
POLR2J -4267.0
PIF1 -4180.0
H4C3 -3847.0
STN1 -3344.0
POT1 -3264.0
NHP2 -2958.0
PCNA -2763.0
POLR2H -2702.0
GAR1 -2665.0
H4C6 -2615.0
RPA2 -2350.0
H4C12 -2167.0
RFC2 -1857.0
FEN1 -1752.0
H2BC12 -1743.0
POLA2 -1268.0
H4C16 -1250.0
H2AC4 -1132.0
RPA3 -1106.0
CTC1 -853.0
RTEL1 -797.0
H4C11 -494.0
TINF2 -406.0
H2BC11 -106.0
TERF2IP -95.0
H2BC9 36.5
PRIM2 76.0
RUVBL2 158.0
H2AZ2 203.0
WRAP53 205.0
POLR2K 272.0
CDK2 273.0
POLR2F 466.0
H4C5 481.0
RFC4 617.0
RFC3 775.0
H2BC10 1117.0
RFC5 1138.0
POLD4 1139.0
H2AJ 1474.0
DAXX 2017.0
H4C2 2031.0
PPP6R3 2078.0
H4C13 2526.0
H2BC17 2583.0
WRN 2634.0
PPP6C 2856.0
TEN1 3051.0
POLR2I 3271.0
POLR2C 3538.0
RFC1 3816.0
H2BC15 3952.0
H2BC5 4154.0
DSCC1 4262.0
BLM 4939.0
CCNA2 5812.0
NOP10 5826.0
H2BC6 5880.0
H3-3A 6189.0
H4C8 6856.0
POLR2D 7144.0
H2AZ1 8703.0
H2BC13 8750.0
CCNA1 8842.0
POLR2G 9042.0
H2AC6 9114.0
H2BC4 9890.0


REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ACETYLATION

REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ACETYLATION
1070
set REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ACETYLATION
setSize 29
pANOVA 0.00696
s.dist -0.29
p.adjustANOVA 0.342



Top enriched genes

Top 20 genes
GeneID Gene Rank
AKT2 -9950
BRPF1 -9476
ING2 -8788
ING5 -8414
PIP4P1 -7818
KAT6A -7816
AKT1 -7654
BRD7 -7608
EP300 -7432
PIP4K2A -7344
GATAD2A -7114
BRD1 -6812
HDAC1 -6364
CHD3 -5673
TP53 -5513
MBD3 -5200
MEAF6 -1421
PML -1375
AKT3 -1295
PIP4K2C -839

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
AKT2 -9950
BRPF1 -9476
ING2 -8788
ING5 -8414
PIP4P1 -7818
KAT6A -7816
AKT1 -7654
BRD7 -7608
EP300 -7432
PIP4K2A -7344
GATAD2A -7114
BRD1 -6812
HDAC1 -6364
CHD3 -5673
TP53 -5513
MBD3 -5200
MEAF6 -1421
PML -1375
AKT3 -1295
PIP4K2C -839
BRPF3 -745
CHD4 1053
PIN1 1294
MAP2K6 1531
MTA2 2290
PIP4K2B 2681
GATAD2B 3828
RBBP4 5414
HDAC2 6519


REACTOME_ANCHORING_OF_THE_BASAL_BODY_TO_THE_PLASMA_MEMBRANE

REACTOME_ANCHORING_OF_THE_BASAL_BODY_TO_THE_PLASMA_MEMBRANE
906
set REACTOME_ANCHORING_OF_THE_BASAL_BODY_TO_THE_PLASMA_MEMBRANE
setSize 93
pANOVA 0.00696
s.dist -0.162
p.adjustANOVA 0.342



Top enriched genes

Top 20 genes
GeneID Gene Rank
CEP89 -10204
KIF24 -9971
MAPRE1 -9576
NPHP4 -9129
CEP72 -8985
PCNT -8980
TMEM67 -8973
CEP41 -8908
NEK2 -8647
CEP83 -8520
CSNK1D -8377
CEP57 -8242
HAUS5 -8108
CEP192 -7901
DYNC1I2 -7729
CCP110 -7536
DYNC1H1 -7456
PLK4 -6912
PAFAH1B1 -6772
CEP97 -6424

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CEP89 -10204
KIF24 -9971
MAPRE1 -9576
NPHP4 -9129
CEP72 -8985
PCNT -8980
TMEM67 -8973
CEP41 -8908
NEK2 -8647
CEP83 -8520
CSNK1D -8377
CEP57 -8242
HAUS5 -8108
CEP192 -7901
DYNC1I2 -7729
CCP110 -7536
DYNC1H1 -7456
PLK4 -6912
PAFAH1B1 -6772
CEP97 -6424
SSNA1 -6279
HAUS8 -6193
NDE1 -6187
CEP76 -6152
YWHAE -5897
CEP63 -5505
TCTN1 -5471
CNTRL -5234
CEP43 -4867
NPHP1 -4726
HSP90AA1 -4552
ACTR1A -4420
TCTN2 -4380
ODF2 -4375
PCM1 -4344
PRKACA -4231
RAB8A -4154
HAUS2 -4128
SCLT1 -3942
CEP70 -3812
IQCB1 -3410
CEP250 -3379
CEP152 -3329
CENPJ -2940
CSNK1E -2909
TUBA1A -2863
TUBB4A -2409
MARK4 -2309
CEP131 -2181
SFI1 -2028
CEP78 -2019
TTBK2 -1939
CEP162 -1646
RAB11A -1584
NEDD1 -1360
RAB3IP -1327
HAUS3 -886
CC2D2A -805
CEP164 -710
ALMS1 -387
CDK1 -191
DYNLL1 -62
CKAP5 -58
FBF1 66
YWHAG 239
PPP2R1A 545
HAUS4 922
TUBB4B 988
CLASP1 1087
TUBB 1258
CDK5RAP2 1425
B9D2 1534
DCTN3 1620
TUBG1 1796
C2CD3 2469
PLK1 3043
NINL 3228
PRKAR2B 3261
CEP135 3662
DCTN1 3760
B9D1 4024
HAUS1 4455
AHI1 4567
SDCCAG8 4878
AKAP9 5256
CEP290 5498
HAUS6 5843
DCTN2 7748
TCTN3 8062
TUBA4A 8277
RPGRIP1L 8694
MKS1 9397
TMEM216 9425


REACTOME_NUCLEOTIDE_EXCISION_REPAIR

REACTOME_NUCLEOTIDE_EXCISION_REPAIR
1021
set REACTOME_NUCLEOTIDE_EXCISION_REPAIR
setSize 107
pANOVA 0.00708
s.dist -0.151
p.adjustANOVA 0.342



Top enriched genes

Top 20 genes
GeneID Gene Rank
UBE2V2 -10249
PPIE -10203
ERCC2 -9851
POLD2 -9835
SUMO2 -9534
ACTR8 -9452
XPC -9366
POLD1 -9280
GTF2H5 -9200
UVSSA -8917
YY1 -8726
LIG1 -8555
POLR2A -8553
PARP1 -8387
UBE2I -8199
PIAS3 -8143
MCRS1 -7889
POLD3 -7854
XAB2 -7805
RUVBL1 -7570

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
UBE2V2 -10249
PPIE -10203
ERCC2 -9851
POLD2 -9835
SUMO2 -9534
ACTR8 -9452
XPC -9366
POLD1 -9280
GTF2H5 -9200
UVSSA -8917
YY1 -8726
LIG1 -8555
POLR2A -8553
PARP1 -8387
UBE2I -8199
PIAS3 -8143
MCRS1 -7889
POLD3 -7854
XAB2 -7805
RUVBL1 -7570
EP300 -7432
POLR2B -7177
COPS7A -6949
INO80 -6751
POLE -6750
USP7 -6707
ERCC4 -6548
NFRKB -6419
RPA1 -5995
XRCC1 -5898
COPS3 -5740
INO80E -5576
ACTL6A -5563
GPS1 -5522
POLR2E -5379
INO80D -5106
POLR2L -5100
ELL -4716
DDB1 -4563
LIG3 -4480
POLR2J -4267
COPS6 -3982
POLE3 -3924
UBC -3749
CUL4A -3734
SUMO1 -3709
ERCC6 -3495
GTF2H1 -3451
INO80B -3287
PCNA -2763
POLR2H -2702
RPA2 -2350
ACTR5 -2227
RAD23B -2036
RFC2 -1857
ERCC8 -1680
TCEA1 -1654
ERCC5 -1643
AQR -1414
POLK -1351
RPA3 -1106
DDB2 -1046
UBB -760
POLE2 -740
GTF2H4 -651
COPS5 -435
PARP2 -209
COPS7B -170
TFPT 54
COPS4 89
RPS27A 210
POLR2K 272
POLR2F 466
ZNF830 570
RFC4 617
RFC3 775
RFC5 1138
POLD4 1139
GTF2H3 1518
ISY1 1657
SUMO3 1932
COPS8 2067
MNAT1 2265
USP45 2476
POLE4 2477
CCNH 3184
POLR2I 3271
PRPF19 3307
POLR2C 3538
CDK7 3661
RFC1 3816
RBX1 3985
COPS2 4894
XPA 5310
INO80C 5883
PIAS1 6280
RNF111 6411
CHD1L 7049
ERCC1 7111
POLR2D 7144
HMGN1 7398
ACTB 7403
UBA52 7581
ERCC3 7596
UBE2N 8089
POLR2G 9042
RAD23A 9456


REACTOME_MEIOSIS

REACTOME_MEIOSIS
138
set REACTOME_MEIOSIS
setSize 110
pANOVA 0.0076
s.dist -0.147
p.adjustANOVA 0.353



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC3 -11072.0
PRDM9 -10877.0
H3C3 -10752.0
H3C6 -10696.0
SYCP1 -10277.0
H2BC26 -10276.0
H2AC7 -10188.5
H2BC7 -10188.5
H2AC20 -10070.0
H2AC14 -9995.0
H3-4 -9817.0
H3C4 -9701.0
SYCP2 -9526.0
SUN2 -9039.0
H2AC18 -9031.5
H2AC19 -9031.5
TERF1 -8662.0
H3C1 -8260.0
H2BC14 -8236.0
UBE2I -8199.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC3 -11072.0
PRDM9 -10877.0
H3C3 -10752.0
H3C6 -10696.0
SYCP1 -10277.0
H2BC26 -10276.0
H2AC7 -10188.5
H2BC7 -10188.5
H2AC20 -10070.0
H2AC14 -9995.0
H3-4 -9817.0
H3C4 -9701.0
SYCP2 -9526.0
SUN2 -9039.0
H2AC18 -9031.5
H2AC19 -9031.5
TERF1 -8662.0
H3C1 -8260.0
H2BC14 -8236.0
UBE2I -8199.0
H2AC8 -8007.0
DMC1 -7964.0
H4C1 -7768.0
H2AX -7754.0
H2BC8 -7687.0
H2BC21 -7485.0
H3C11 -7455.0
TEX12 -7430.0
ACD -7311.5
MND1 -6876.0
TERF2 -6723.0
MSH5 -6034.0
RPA1 -5995.0
DIDO1 -5961.0
RAD51 -5528.0
H4C4 -5408.0
H2BC1 -5406.0
NBN -5357.0
H4C9 -5033.0
H3-3B -4811.0
SUN1 -4675.0
SYCP3 -4192.0
H4C3 -3847.0
SMC3 -3481.0
SMC1B -3476.0
SYCE1 -3369.0
POT1 -3264.0
STAG1 -3209.0
RAD51C -3047.0
SYCE2 -3046.0
SYNE2 -2904.0
ATM -2840.0
H4C6 -2615.0
TOP3A -2386.0
RPA2 -2350.0
CDK4 -2328.0
H4C12 -2167.0
H2BC12 -1743.0
H4C16 -1250.0
SYNE1 -1177.0
H2AC4 -1132.0
RPA3 -1106.0
ATR -1075.0
H3C8 -1035.0
MLH3 -640.0
H4C11 -494.0
TINF2 -406.0
MSH4 -382.0
H2BC11 -106.0
TERF2IP -95.0
H2BC9 36.5
H3C7 36.5
MRE11 41.0
H2AZ2 203.0
BRCA1 231.0
CDK2 273.0
H4C5 481.0
PSMC3IP 1082.0
H2BC10 1117.0
MLH1 1361.0
H2AJ 1474.0
H4C2 2031.0
HSPA2 2109.0
RAD50 2206.0
H4C13 2526.0
H2BC17 2583.0
REC8 3421.0
H2BC15 3952.0
H2BC5 4154.0
H3C2 4334.0
LMNA 4450.0
BLM 4939.0
RAD21 5122.0
H2BC6 5880.0
H3-3A 6189.0
RBBP8 6725.0
H4C8 6856.0
TEX15 6962.0
LMNB1 7206.0
SYCE3 7261.0
BRCA2 7348.0
STAG3 7541.0
H3C10 8230.0
SPO11 8429.0
H2AZ1 8703.0
H2BC13 8750.0
FKBP6 9094.0
H2AC6 9114.0
H2BC4 9890.0
H3C12 10509.0


REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX

REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX
35
set REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX
setSize 57
pANOVA 0.00773
s.dist -0.204
p.adjustANOVA 0.353



Top enriched genes

Top 20 genes
GeneID Gene Rank
NELFB -10260
CDK9 -10225
ERCC2 -9851
LEO1 -9537
GTF2H5 -9200
SKIC8 -9165
CDC73 -9111
NELFA -9009
POLR2A -8553
MLLT1 -7738
CTDP1 -7331
SSRP1 -7224
POLR2B -7177
SUPT6H -7069
MLLT3 -6135
NELFE -5945
CCNT1 -5556
POLR2E -5379
CCNT2 -5366
CTR9 -5125

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NELFB -10260
CDK9 -10225
ERCC2 -9851
LEO1 -9537
GTF2H5 -9200
SKIC8 -9165
CDC73 -9111
NELFA -9009
POLR2A -8553
MLLT1 -7738
CTDP1 -7331
SSRP1 -7224
POLR2B -7177
SUPT6H -7069
MLLT3 -6135
NELFE -5945
CCNT1 -5556
POLR2E -5379
CCNT2 -5366
CTR9 -5125
POLR2L -5100
ELL -4716
ELOB -4550
AFF4 -4377
GTF2F1 -4288
POLR2J -4267
NCBP2 -3923
RTF1 -3852
GTF2H1 -3451
SUPT5H -2836
IWS1 -2834
ELOA2 -2754
POLR2H -2702
EAF1 -2450
EAF2 -2244
GTF2F2 -1683
TCEA1 -1654
GTF2H4 -651
POLR2K 272
POLR2F 466
PAF1 1140
ELOA 1348
GTF2H3 1518
MNAT1 2265
ELOC 2558
SUPT16H 2616
CCNH 3184
POLR2I 3271
POLR2C 3538
CDK7 3661
NCBP1 4784
NELFCD 4792
CCNK 5306
SUPT4H1 5926
POLR2D 7144
ERCC3 7596
POLR2G 9042


REACTOME_HOMOLOGY_DIRECTED_REPAIR

REACTOME_HOMOLOGY_DIRECTED_REPAIR
1010
set REACTOME_HOMOLOGY_DIRECTED_REPAIR
setSize 132
pANOVA 0.00797
s.dist -0.134
p.adjustANOVA 0.354



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC3 -11072.0
PIAS4 -10499.0
H2BC26 -10276.0
UBE2V2 -10249.0
H2BC7 -10188.5
POLD2 -9835.0
H3-4 -9817.0
CLSPN -9799.0
RNF168 -9652.0
HERC2 -9585.0
RNF4 -9539.0
SUMO2 -9534.0
SIRT6 -9353.0
POLD1 -9280.0
RMI2 -8964.0
DNA2 -8554.0
PARP1 -8387.0
RNF8 -8282.0
H2BC14 -8236.0
UBE2I -8199.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC3 -11072.0
PIAS4 -10499.0
H2BC26 -10276.0
UBE2V2 -10249.0
H2BC7 -10188.5
POLD2 -9835.0
H3-4 -9817.0
CLSPN -9799.0
RNF168 -9652.0
HERC2 -9585.0
RNF4 -9539.0
SUMO2 -9534.0
SIRT6 -9353.0
POLD1 -9280.0
RMI2 -8964.0
DNA2 -8554.0
PARP1 -8387.0
RNF8 -8282.0
H2BC14 -8236.0
UBE2I -8199.0
RAD52 -7959.0
POLD3 -7854.0
H4C1 -7768.0
H2AX -7754.0
H2BC8 -7687.0
H2BC21 -7485.0
XRCC2 -7347.0
RHNO1 -6956.0
NSD2 -6909.0
POLE -6750.0
TIMELESS -6646.0
RAD9A -6607.0
ERCC4 -6548.0
ABRAXAS1 -6006.0
RPA1 -5995.0
POLH -5972.0
XRCC1 -5898.0
MUS81 -5590.0
KAT5 -5557.0
RAD51 -5528.0
H4C4 -5408.0
H2BC1 -5406.0
NBN -5357.0
MDC1 -5348.0
H4C9 -5033.0
UIMC1 -4967.0
TIPIN -4942.0
RAD51D -4806.0
LIG3 -4480.0
POLE3 -3924.0
H4C3 -3847.0
UBC -3749.0
TOPBP1 -3164.0
RAD51C -3047.0
ABL1 -2852.0
ATM -2840.0
PCNA -2763.0
H4C6 -2615.0
TOP3A -2386.0
RPA2 -2350.0
CHEK1 -2287.0
H4C12 -2167.0
RFC2 -1857.0
FEN1 -1752.0
H2BC12 -1743.0
HUS1 -1475.0
POLK -1351.0
POLQ -1281.0
H4C16 -1250.0
EME2 -1224.0
RPA3 -1106.0
ATR -1075.0
PALB2 -890.0
RTEL1 -797.0
UBB -760.0
POLE2 -740.0
EXO1 -533.0
H4C11 -494.0
RAD9B -363.0
PARP2 -209.0
ATRIP -199.0
H2BC11 -106.0
H2BC9 36.5
MRE11 41.0
RPS27A 210.0
BRCA1 231.0
CDK2 273.0
H4C5 481.0
RAD51B 496.0
BARD1 611.0
RFC4 617.0
RFC3 775.0
H2BC10 1117.0
RFC5 1138.0
POLD4 1139.0
H4C2 2031.0
RAD50 2206.0
RAD17 2339.0
POLE4 2477.0
H4C13 2526.0
H2BC17 2583.0
WRN 2634.0
RAD51AP1 2923.0
GEN1 3323.0
BABAM2 3586.0
SLX4 3596.0
RFC1 3816.0
TP53BP1 3925.0
H2BC15 3952.0
EME1 4012.0
PPP4C 4091.0
H2BC5 4154.0
RAD1 4287.0
BLM 4939.0
SEM1 5155.0
XRCC3 5596.0
CCNA2 5812.0
H2BC6 5880.0
RMI1 5934.0
SPIDR 6014.0
RBBP8 6725.0
H4C8 6856.0
BABAM1 6905.0
ERCC1 7111.0
BRCA2 7348.0
UBA52 7581.0
PPP4R2 7704.0
BRIP1 7863.0
UBE2N 8089.0
H2BC13 8750.0
CCNA1 8842.0
H2BC4 9890.0


REACTOME_NERVOUS_SYSTEM_DEVELOPMENT

REACTOME_NERVOUS_SYSTEM_DEVELOPMENT
1536
set REACTOME_NERVOUS_SYSTEM_DEVELOPMENT
setSize 552
pANOVA 0.00863
s.dist 0.0654
p.adjustANOVA 0.363



Top enriched genes

Top 20 genes
GeneID Gene Rank
TYROBP 10391
TUBB8 10294
VASP 10280
CD72 10275
HOXA2 10233
RPL10A 10030
TUBA3E 9950
EFNB3 9820
COL9A3 9630
CNTN6 9561
MYL9 9523
RPLP1 9515
PLXNA2 9451
VLDLR 9377
EPHA7 9281
EFNA2 9274
ARTN 9257
SEMA4A 9241
SCN2B 9240
PLXND1 9190

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TYROBP 10391.0
TUBB8 10294.0
VASP 10280.0
CD72 10275.0
HOXA2 10233.0
RPL10A 10030.0
TUBA3E 9950.0
EFNB3 9820.0
COL9A3 9630.0
CNTN6 9561.0
MYL9 9523.0
RPLP1 9515.0
PLXNA2 9451.0
VLDLR 9377.0
EPHA7 9281.0
EFNA2 9274.0
ARTN 9257.0
SEMA4A 9241.0
SCN2B 9240.0
PLXND1 9190.0
FLRT3 9110.0
TUBB6 9036.0
RPL27A 8956.0
RND1 8897.0
PSMA6 8714.0
RPS28 8686.0
PSMB7 8601.0
EPHA2 8577.0
MYL12B 8493.0
RPL17 8465.0
CSNK2A1 8453.0
LHX9 8412.0
PRKAR2A 8317.0
MAGOH 8311.0
GRB7 8300.0
TUBA4A 8277.0
COL4A4 8259.0
PSMB3 8195.0
TUBB1 8143.0
EGFR 8078.0
PSMA1 8054.0
UNC5B 8007.0
RPL38 7924.0
NRAS 7853.0
LIMK2 7849.0
TUBA4B 7781.0
NCAM1 7756.0
RPL36 7752.0
PLXNA4 7747.0
SHC1 7700.0
CAP1 7661.0
ACTR2 7628.0
RPL8 7608.0
GFRA3 7595.0
UBA52 7581.0
EPHB3 7576.0
PFN1 7563.0
COL5A3 7559.0
SCN9A 7528.0
SPTA1 7524.0
TUBB3 7518.0
ACTB 7403.0
RPL32 7322.0
RPL3 7305.0
RPS6KA1 7236.0
RPL29 7214.0
NEO1 7209.0
DOK5 7170.0
NRP1 7145.0
SH3GL2 7098.0
RPL23A 6953.0
DAB1 6941.0
RPL37 6912.0
RPS13 6875.0
PSMA2 6848.0
DPYSL2 6845.0
RASA1 6797.0
FES 6791.0
PSMC2 6774.0
SCD5 6757.0
RPL12 6702.0
PRKACB 6694.0
ADGRV1 6654.0
SIAH2 6612.0
LYPLA2 6594.0
SCN3A 6587.0
TUBA8 6563.0
DSCAML1 6562.0
HDAC2 6519.0
PMP22 6473.0
CLTC 6428.0
PSMB8 6380.0
SEMA4D 6359.0
LHX4 6345.0
EFNB2 6329.0
RPL7A 6303.0
POU3F1 6262.0
CDC42 6209.0
GPC1 6206.0
SRGAP2 6155.0
ABLIM3 6129.0
RPS24 6102.0
GIT1 6045.0
CLTA 6001.0
GAB2 5996.0
SLIT3 5838.0
SOS1 5823.0
CNTN1 5797.0
RPL22L1 5729.0
TIAM1 5679.0
SDCBP 5661.0
PSEN2 5569.0
RPS16 5553.0
MPZ 5522.0
LHX2 5472.0
DNM3 5441.0
DPYSL3 5343.0
PFN2 5216.0
RPL28 5172.0
SEM1 5155.0
KCNQ2 5147.0
KALRN 5111.0
RPS9 5010.0
PIK3R1 4998.0
GDNF 4978.0
RPS6KA4 4931.0
ADGRG6 4928.0
RPS25 4925.0
AP2A1 4899.0
CACNA1I 4893.0
MMP2 4867.0
LYN 4807.0
ITGB1 4790.0
NCBP1 4784.0
GSPT1 4762.0
RBM8A 4753.0
GRB2 4749.0
PSEN1 4717.0
RPL39L 4698.0
PAK5 4685.0
TEAD1 4621.0
GRIN1 4616.0
PSMB4 4596.0
DOK1 4538.0
RRAS 4453.0
SHTN1 4433.0
ARHGAP35 4379.0
ROBO1 4253.0
RPL15 4228.0
AKAP5 4207.0
PSMD14 4205.0
ST8SIA2 4180.0
SCN11A 4170.0
PSMC1 4146.0
KCNQ3 4145.0
ITGA1 4143.0
GSK3B 4099.0
ABLIM1 4047.0
RBX1 3985.0
LAMA2 3970.0
CACNB4 3937.0
GAP43 3857.0
RPL13A 3845.5
RPL27 3820.0
LHX3 3794.0
PSMA7 3774.0
MAPK11 3751.0
CNTNAP1 3743.0
UTRN 3680.0
PSMD4 3652.0
CACNB1 3648.0
HJV 3606.0
DOK6 3580.0
PSPN 3495.0
SLIT2 3477.0
PSMC5 3435.0
HSP90AB1 3410.0
PAK1 3361.0
PIK3CA 3346.0
TRPC4 3340.0
RPL11 3232.0
COL3A1 3229.0
MYH11 3157.0
ITGA5 3123.0
MAPK12 3081.0
SCN8A 3061.0
CACNA1C 3041.0
SCN7A 3025.0
RPL4 3012.0
RPS20 3000.0
NRTN 2972.0
PLXNC1 2918.0
RPL35 2913.0
RPL34 2908.0
MSI1 2857.0
CACNB2 2842.0
PSMD3 2823.0
GAB1 2794.0
SDC2 2781.0
COL6A5 2775.0
RNPS1 2756.0
MAPK8 2729.0
ACTG1 2718.0
SCN1A 2659.0
SRC 2638.0
EZR 2623.0
COL9A2 2602.0
GFRA2 2595.0
CACNA1D 2567.0
ELOC 2558.0
RGMA 2547.0
RPL18A 2540.0
GRB10 2523.0
ROBO3 2511.0
RPL35A 2508.0
UNC5D 2455.0
SIAH1 2426.0
PSMB5 2383.0
TRIO 2327.0
EPHA5 2307.0
SCN4B 2300.0
COL4A1 2196.0
RPS21 2188.0
RPS12 2164.0
ITGA2 2112.0
RPS10 2082.0
SEMA3E 2069.0
PDLIM7 1997.0
ACTR3 1968.0
ROCK1 1951.0
PIK3CB 1937.0
DOK2 1919.0
RPS19 1918.0
SPTBN5 1886.0
RHOC 1875.0
PTPN11 1816.0
MYL6 1722.0
PRNP 1717.0
RPS7 1676.0
MYO10 1672.0
PSME4 1640.0
COL2A1 1613.0
PSMD5 1604.0
ADAM10 1586.0
PRKCA 1517.0
SPTBN1 1498.0
EPHA6 1491.0
PSMB9 1422.0
DOK4 1327.0
MAPK1 1304.0
EPHB1 1267.0
NRP2 1264.0
EPHA4 1252.0
COL4A3 1251.0
EGR2 1214.0
CXCL12 1209.0
NAB1 1197.0
ARPC4 1195.0
DLG4 1172.0
HMGCR 1165.0
RPS6KA2 1136.0
PIK3R2 1089.0
CLASP1 1087.0
RPL30 1060.0
TUBB4B 988.0
PRX 961.0
SEMA7A 956.0
SEMA6D 938.0
EFNA5 910.0
ST8SIA4 896.0
SPTB 891.0
EIF4G1 889.0
TREM2 879.0
SCN4A 856.0
EPHB2 831.0
UPF2 809.0
RPL14 799.0
RPS2 787.0
EPHA10 773.0
DNM1 754.0
RPL7 753.0
MAPK13 743.0
MAG 728.0
RPL23 697.0
AP2S1 663.0
MYO9B 638.0
COL4A2 624.0
NRCAM 616.0
ARHGEF11 596.0
TRPC7 553.0
MYH14 450.0
VAV3 447.0
FRS2 428.0
RPS6KA5 421.0
PSMA4 403.0
CACNA1G 366.0
SRGAP1 328.0
RPL9 293.0
PAK6 287.0
FARP2 270.0
CUL2 238.0
NFASC 228.0
RPS18 225.0
RPS27A 210.0
PTK2 195.0
NGEF 186.0
YAP1 138.0
SPTBN4 108.0
RPSA 85.0
RPL5 -25.0
RPS27L -42.0
ARHGEF12 -83.0
PSMB2 -211.0
CSNK2B -255.0
PSMD11 -313.0
POU3F2 -420.0
CASC3 -424.0
GRIN2B -451.0
PSME2 -465.0
COL5A1 -492.0
RPL36AL -512.5
TRPC6 -534.0
DOCK1 -573.0
YES1 -582.0
DPYSL5 -594.0
SCN1B -619.0
TRPC1 -626.0
NCAN -630.0
PSMC3 -685.0
RPL31 -712.0
VAV2 -718.0
PSMB6 -723.0
UBB -760.0
RPLP0 -801.0
NTN1 -826.0
UNC5C -838.0
UNC5A -882.0
CSNK2A2 -889.0
RPLP2 -896.0
MBP -903.0
ROBO2 -905.0
DSCAM -923.0
MMP9 -947.0
RPL21 -953.0
RPL26 -958.0
COL9A1 -1000.0
TUBA1B -1007.0
SLIT1 -1018.0
GFRA1 -1023.0
RPS8 -1044.0
LIMK1 -1145.0
MYL12A -1147.0
ARPC3 -1148.0
COL6A6 -1171.0
DCC -1198.0
ALCAM -1204.0
PSMB1 -1423.0
ANK3 -1433.0
NELL2 -1472.0
PRKACG -1720.0
RHOA -1807.0
ARHGEF28 -1809.0
RPL18 -1942.0
DLG1 -1956.0
EPHA1 -2012.0
ABLIM2 -2013.0
PSMA3 -2026.0
APH1B -2030.0
PRKCQ -2103.0
RAC1 -2129.0
SREBF2 -2175.0
CXCR4 -2279.0
PLXNA1 -2282.0
ANK1 -2316.0
TUBB4A -2409.0
MAPK14 -2455.0
PIK3R3 -2476.0
RPS27 -2513.0
ITGA2B -2543.0
ARHGAP39 -2595.0
ISL1 -2605.0
DNM2 -2651.0
PSMB10 -2660.0
ANK2 -2783.0
EPHA8 -2817.0
ABL2 -2846.0
ABL1 -2852.0
TUBA1A -2863.0
CACNA1S -2924.0
LAMA1 -2935.0
SCN2A -2937.0
WWTR1 -2968.0
LDB1 -2984.0
TUBA1C -2997.0
RPL13 -3022.0
COL5A2 -3182.0
RET -3224.0
MAGOHB -3261.0
TUBA3C -3266.0
HSPA8 -3316.0
NCSTN -3348.0
TUBB2A -3433.0
ARPC2 -3442.0
MYH10 -3520.0
PIP5K1C -3537.0
TRPC3 -3551.0
SHC3 -3556.0
RPS11 -3646.0
NTN4 -3672.0
ROCK2 -3673.0
EFNA3 -3715.0
ITGB3 -3725.0
NCK1 -3736.0
UBC -3749.0
SRGAP3 -3783.0
RPS15A -3879.0
NCBP2 -3923.0
MAPK7 -3992.0
FAU -4041.0
PSMD6 -4053.0
PPP3CB -4085.0
PRKACA -4231.0
ITSN1 -4234.0
PSMA5 -4249.0
FYN -4258.0
RPS3 -4268.0
RELN -4276.0
RPL41 -4291.0
AP2A2 -4338.0
ITGA9 -4364.0
COL6A2 -4445.0
KRAS -4450.0
MAP2K2 -4538.0
RGMB -4545.0
ELOB -4550.0
HSP90AA1 -4552.0
PIK3CD -4597.0
RPS6 -4622.0
PSMD8 -4639.0
PSMD7 -4693.0
PSMA8 -4702.0
ENAH -4741.0
PTPRA -4828.0
SEMA3A -4866.0
RPL6 -4911.0
RPS3A -4938.0
LAMC1 -4954.0
CRMP1 -4978.0
PSMC4 -5080.0
CLTB -5089.0
PAK2 -5107.0
PLXNB1 -5139.0
AP2B1 -5173.0
PTPRC -5207.0
RPS26 -5257.0
CAP2 -5333.0
SEMA6A -5338.0
CREB1 -5377.0
MET -5396.0
CHL1 -5436.0
RHOB -5521.0
CNTN2 -5550.0
DAG1 -5610.0
RAP1GAP -5620.0
MAP2K1 -5708.0
EFNA1 -5728.0
ITGAV -5756.0
TLN1 -5759.0
SCN3B -5779.0
TUBB2B -5782.0
ARHGEF7 -5798.0
COL6A1 -5884.0
RPL26L1 -5886.0
AGAP2 -6029.0
ETF1 -6036.0
CLASP2 -6038.0
NUMB -6059.0
CACNA1H -6065.0
RPS29 -6101.0
ERBB2 -6120.0
CDK5 -6162.0
CFL1 -6192.0
PSMC6 -6194.0
DPYSL4 -6341.0
LAMB1 -6347.0
PSMD9 -6362.0
PSENEN -6381.0
ARPC1B -6450.0
CACNB3 -6537.0
MAPK3 -6553.0
UPF3A -6804.0
IRS2 -6927.0
SOX10 -7135.0
PLCG1 -7205.0
RPL19 -7259.0
SEMA5A -7380.0
SCN10A -7414.0
MYH9 -7450.0
NAB2 -7464.0
SOS2 -7482.0
PSME3 -7537.0
RPS23 -7595.0
TUBAL3 -7648.0
PSMD1 -7718.0
CYP51A1 -7775.0
EPHB4 -7804.0
RPL24 -7908.0
WASL -7917.0
RDX -7974.0
EPHA3 -7988.0
HRAS -8010.0
EFNA4 -8034.0
PABPC1 -8095.0
AP2M1 -8109.0
ARPC1A -8248.0
ITGA10 -8287.0
COL6A3 -8308.0
GFRA4 -8447.0
RPS5 -8455.0
ARPC5 -8477.0
NCK2 -8483.0
AGRN -8546.0
FGFR1 -8617.0
PSMD12 -8730.0
CLTCL1 -8736.0
EVL -8755.0
EIF4A3 -8959.0
EPHB6 -9082.0
PSMD13 -9136.0
SPTBN2 -9143.0
PSMF1 -9180.0
RPL37A -9220.0
APH1A -9231.0
RANBP9 -9240.0
PAK4 -9310.0
USP33 -9333.0
SMARCA4 -9405.0
SCN5A -9414.0
RPS15 -9442.0
RPS14 -9594.0
RPL3L -9803.0
PITPNA -9811.0
CDK5R1 -10016.0
SPTAN1 -10082.0
PSMB11 -10116.0
TUBA3D -10142.0
RPL22 -10230.0
PSME1 -10255.0
RPL10L -10366.0
ZSWIM8 -10584.0
KIF4B -10689.0
PSMD2 -10774.0


REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION

REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION
437
set REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION
setSize 138
pANOVA 0.00875
s.dist -0.129
p.adjustANOVA 0.363



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC3 -11072.0
H3C3 -10752.0
H3C6 -10696.0
H2BC26 -10276.0
H2AC7 -10188.5
H2BC7 -10188.5
H2AC20 -10070.0
TAF1C -10027.0
H2AC14 -9995.0
ERCC2 -9851.0
H3C4 -9701.0
SAP18 -9501.0
GTF2H5 -9200.0
H2AC18 -9031.5
H2AC19 -9031.5
MBD2 -8922.0
DNMT3L -8324.0
TET3 -8304.0
H3C1 -8260.0
H2BC14 -8236.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC3 -11072.0
H3C3 -10752.0
H3C6 -10696.0
H2BC26 -10276.0
H2AC7 -10188.5
H2BC7 -10188.5
H2AC20 -10070.0
TAF1C -10027.0
H2AC14 -9995.0
ERCC2 -9851.0
H3C4 -9701.0
SAP18 -9501.0
GTF2H5 -9200.0
H2AC18 -9031.5
H2AC19 -9031.5
MBD2 -8922.0
DNMT3L -8324.0
TET3 -8304.0
H3C1 -8260.0
H2BC14 -8236.0
H2AC8 -8007.0
SIN3B -7876.0
H4C1 -7768.0
H2AX -7754.0
H2BC8 -7687.0
H2BC21 -7485.0
H3C11 -7455.0
EP300 -7432.0
GATAD2A -7114.0
KAT2A -7092.0
EHMT2 -6790.0
MYBBP1A -6666.0
MTA1 -6546.0
POLR1E -6438.0
SUDS3 -6371.0
HDAC1 -6364.0
KAT2B -5792.0
CHD3 -5673.0
H4C4 -5408.0
H2BC1 -5406.0
POLR2E -5379.0
MBD3 -5200.0
POLR2L -5100.0
H4C9 -5033.0
EZH2 -4861.0
H3-3B -4811.0
PHF1 -4666.0
TBP -4306.0
MTF2 -4223.0
SF3B1 -3956.0
DDX21 -3912.0
H4C3 -3847.0
ERCC6 -3495.0
GTF2H1 -3451.0
ARID4B -3376.0
AEBP2 -3220.0
POLR1H -2961.0
JARID2 -2934.0
POLR2H -2702.0
H4C6 -2615.0
TAF1A -2352.0
POLR1B -2260.0
H4C12 -2167.0
CBX3 -2137.0
MYO1C -1897.0
UHRF1 -1799.0
H2BC12 -1743.0
SIRT1 -1495.0
H4C16 -1250.0
H2AC4 -1132.0
H3C8 -1035.0
UBTF -954.0
TAF1B -881.0
DEK -782.0
GTF2H4 -651.0
SAP30 -541.0
H4C11 -494.0
DNMT3A -476.0
TET2 -294.0
DNMT3B -134.0
H2BC11 -106.0
H2BC9 36.5
H3C7 36.5
POLR1A 168.0
H2AZ2 203.0
POLR2K 272.0
BAZ2A 357.0
POLR2F 466.0
H4C5 481.0
DNMT1 713.0
RRP8 950.0
TTF1 1024.0
SAP30L 1031.0
CHD4 1053.0
H2BC10 1117.0
EED 1128.0
MTA3 1224.0
SIN3A 1355.0
SAP130 1467.0
H2AJ 1474.0
GTF2H3 1518.0
BAZ1B 1529.0
TET1 1754.0
H4C2 2031.0
TDG 2234.0
MNAT1 2265.0
MTA2 2290.0
SUZ12 2417.0
SMARCA5 2520.0
H4C13 2526.0
H2BC17 2583.0
POLR1D 3112.0
CCNH 3184.0
POLR1F 3218.0
CDK7 3661.0
GATAD2B 3828.0
H2BC15 3952.0
GSK3B 4099.0
PHF19 4113.0
H2BC5 4154.0
POLR1C 4240.0
H3C2 4334.0
SAP30BP 4611.0
RBBP4 5414.0
H2BC6 5880.0
H3-3A 6189.0
TAF1D 6507.0
HDAC2 6519.0
H4C8 6856.0
ACTB 7403.0
ERCC3 7596.0
H3C10 8230.0
H2AZ1 8703.0
H2BC13 8750.0
POLR1G 9058.0
H2AC6 9114.0
H2BC4 9890.0
H3C12 10509.0


REACTOME_ASSEMBLY_OF_ACTIVE_LPL_AND_LIPC_LIPASE_COMPLEXES

REACTOME_ASSEMBLY_OF_ACTIVE_LPL_AND_LIPC_LIPASE_COMPLEXES
1326
set REACTOME_ASSEMBLY_OF_ACTIVE_LPL_AND_LIPC_LIPASE_COMPLEXES
setSize 18
pANOVA 0.00974
s.dist -0.352
p.adjustANOVA 0.363



Top enriched genes

Top 20 genes
GeneID Gene Rank
ANGPTL8 -11103
FURIN -10505
APOA4 -10357
FGF21 -10309
APOA5 -10266
LMF2 -9389
APOC2 -8192
PCSK6 -6003
ANGPTL3 -5640
GPIHBP1 -5278
LMF1 -4351
MBTPS1 -4061
CREB3L3 -3180
ANGPTL4 1839
LPL 4610
CIDEC 5423
PCSK5 6123
LIPC 6169

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ANGPTL8 -11103
FURIN -10505
APOA4 -10357
FGF21 -10309
APOA5 -10266
LMF2 -9389
APOC2 -8192
PCSK6 -6003
ANGPTL3 -5640
GPIHBP1 -5278
LMF1 -4351
MBTPS1 -4061
CREB3L3 -3180
ANGPTL4 1839
LPL 4610
CIDEC 5423
PCSK5 6123
LIPC 6169


REACTOME_LDL_REMODELING

REACTOME_LDL_REMODELING
1334
set REACTOME_LDL_REMODELING
setSize 6
pANOVA 0.0098
s.dist 0.609
p.adjustANOVA 0.363



Top enriched genes

Top 20 genes
GeneID Gene Rank
P4HB 9604
LPA 9266
CETP 8403
APOB 7310
APOF 3048
MTTP 949

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
P4HB 9604
LPA 9266
CETP 8403
APOB 7310
APOF 3048
MTTP 949


REACTOME_AURKA_ACTIVATION_BY_TPX2

REACTOME_AURKA_ACTIVATION_BY_TPX2
1238
set REACTOME_AURKA_ACTIVATION_BY_TPX2
setSize 69
pANOVA 0.00986
s.dist -0.18
p.adjustANOVA 0.363



Top enriched genes

Top 20 genes
GeneID Gene Rank
MAPRE1 -9576
CEP72 -8985
PCNT -8980
CEP41 -8908
NEK2 -8647
CSNK1D -8377
CEP57 -8242
HAUS5 -8108
CEP192 -7901
DYNC1I2 -7729
CCP110 -7536
DYNC1H1 -7456
PLK4 -6912
PAFAH1B1 -6772
SSNA1 -6279
HAUS8 -6193
NDE1 -6187
CEP76 -6152
YWHAE -5897
CEP63 -5505

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MAPRE1 -9576
CEP72 -8985
PCNT -8980
CEP41 -8908
NEK2 -8647
CSNK1D -8377
CEP57 -8242
HAUS5 -8108
CEP192 -7901
DYNC1I2 -7729
CCP110 -7536
DYNC1H1 -7456
PLK4 -6912
PAFAH1B1 -6772
SSNA1 -6279
HAUS8 -6193
NDE1 -6187
CEP76 -6152
YWHAE -5897
CEP63 -5505
CNTRL -5234
CEP43 -4867
HSP90AA1 -4552
HMMR -4540
ACTR1A -4420
ODF2 -4375
PCM1 -4344
PRKACA -4231
HAUS2 -4128
CEP70 -3812
CEP250 -3379
CEP152 -3329
CENPJ -2940
CSNK1E -2909
TUBA1A -2863
TUBB4A -2409
CEP131 -2181
SFI1 -2028
CEP78 -2019
NEDD1 -1360
HAUS3 -886
CEP164 -710
AURKA -540
ALMS1 -387
CDK1 -191
TPX2 -149
DYNLL1 -62
CKAP5 -58
YWHAG 239
PPP2R1A 545
HAUS4 922
TUBB4B 988
CLASP1 1087
TUBB 1258
CDK5RAP2 1425
DCTN3 1620
TUBG1 1796
PLK1 3043
NINL 3228
PRKAR2B 3261
CEP135 3662
DCTN1 3760
HAUS1 4455
SDCCAG8 4878
AKAP9 5256
CEP290 5498
HAUS6 5843
DCTN2 7748
TUBA4A 8277


REACTOME_MEIOTIC_SYNAPSIS

REACTOME_MEIOTIC_SYNAPSIS
54
set REACTOME_MEIOTIC_SYNAPSIS
setSize 73
pANOVA 0.01
s.dist -0.174
p.adjustANOVA 0.363



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC3 -11072.0
SYCP1 -10277.0
H2BC26 -10276.0
H2AC7 -10188.5
H2BC7 -10188.5
H2AC20 -10070.0
H2AC14 -9995.0
H3-4 -9817.0
SYCP2 -9526.0
SUN2 -9039.0
H2AC18 -9031.5
H2AC19 -9031.5
TERF1 -8662.0
H2BC14 -8236.0
UBE2I -8199.0
H2AC8 -8007.0
H4C1 -7768.0
H2AX -7754.0
H2BC8 -7687.0
H2BC21 -7485.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC3 -11072.0
SYCP1 -10277.0
H2BC26 -10276.0
H2AC7 -10188.5
H2BC7 -10188.5
H2AC20 -10070.0
H2AC14 -9995.0
H3-4 -9817.0
SYCP2 -9526.0
SUN2 -9039.0
H2AC18 -9031.5
H2AC19 -9031.5
TERF1 -8662.0
H2BC14 -8236.0
UBE2I -8199.0
H2AC8 -8007.0
H4C1 -7768.0
H2AX -7754.0
H2BC8 -7687.0
H2BC21 -7485.0
TEX12 -7430.0
ACD -7311.5
TERF2 -6723.0
DIDO1 -5961.0
H4C4 -5408.0
H2BC1 -5406.0
H4C9 -5033.0
SUN1 -4675.0
SYCP3 -4192.0
H4C3 -3847.0
SMC3 -3481.0
SMC1B -3476.0
SYCE1 -3369.0
POT1 -3264.0
STAG1 -3209.0
SYCE2 -3046.0
SYNE2 -2904.0
H4C6 -2615.0
H4C12 -2167.0
H2BC12 -1743.0
H4C16 -1250.0
SYNE1 -1177.0
H2AC4 -1132.0
ATR -1075.0
H4C11 -494.0
TINF2 -406.0
H2BC11 -106.0
TERF2IP -95.0
H2BC9 36.5
H2AZ2 203.0
BRCA1 231.0
H4C5 481.0
H2BC10 1117.0
H2AJ 1474.0
H4C2 2031.0
HSPA2 2109.0
H4C13 2526.0
H2BC17 2583.0
REC8 3421.0
H2BC15 3952.0
H2BC5 4154.0
LMNA 4450.0
RAD21 5122.0
H2BC6 5880.0
H4C8 6856.0
LMNB1 7206.0
SYCE3 7261.0
STAG3 7541.0
H2AZ1 8703.0
H2BC13 8750.0
FKBP6 9094.0
H2AC6 9114.0
H2BC4 9890.0


REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS

REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS
662
set REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS
setSize 14
pANOVA 0.0105
s.dist 0.395
p.adjustANOVA 0.363



Top enriched genes

Top 20 genes
GeneID Gene Rank
CYSLTR2 9245
TBXA2R 8693
PTGER1 8154
OXER1 7232
PTGFR 6984
LTB4R 6644
PTGER4 6466
PTGDR2 6450
PTGER3 3020
PTGER2 2987
LTB4R2 1954
GPR17 156
PTGDR 124
PTGIR -11030

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CYSLTR2 9245
TBXA2R 8693
PTGER1 8154
OXER1 7232
PTGFR 6984
LTB4R 6644
PTGER4 6466
PTGDR2 6450
PTGER3 3020
PTGER2 2987
LTB4R2 1954
GPR17 156
PTGDR 124
PTGIR -11030


REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS

REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS
601
set REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS
setSize 188
pANOVA 0.0105
s.dist 0.108
p.adjustANOVA 0.363



Top enriched genes

Top 20 genes
GeneID Gene Rank
ACKR4 10585
CXCR2 10434
CCL3 10370
MC5R 10281
PPBP 10229
CCL5 10217
CCL2 10159
C5AR1 10139
MLN 10135
KEL 9990
CCL19 9979
KISS1R 9974
CCR3 9939
APLNR 9917
NMUR2 9785
ACKR1 9728
TACR3 9702
PDYN 9668
GALR2 9614
CXCL5 9518

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ACKR4 10585
CXCR2 10434
CCL3 10370
MC5R 10281
PPBP 10229
CCL5 10217
CCL2 10159
C5AR1 10139
MLN 10135
KEL 9990
CCL19 9979
KISS1R 9974
CCR3 9939
APLNR 9917
NMUR2 9785
ACKR1 9728
TACR3 9702
PDYN 9668
GALR2 9614
CXCL5 9518
CXCL11 9458
NPB 9422
CXCL16 9408
MCHR1 9331
RXFP4 9311
NPY 9231
CXCL2 9177
NTS 9077
UTS2R 9028
C5AR2 8834
NMU 8819
CCR5 8539
TAC1 8510
EDNRA 8456
CCL23 8436
AVP 8433
HCRTR2 8303
NPBWR1 8301
NPY1R 8090
RLN2 8043
NPY2R 7871
NPY5R 7802
AVPR1A 7684
GALR1 7485
GHSR 7406
CCR10 7336
CCL1 7220
POMC 7181
CXCL3 7143
MC2R 7071
ACKR3 7039
PENK 6854
CXCL6 6548
C5 6404
NPFF 6400
CCL22 6316
SSTR1 6113
UTS2B 6039
RLN3 5954
TRH 5899
PYY 5720
OPRL1 5265
CX3CR1 5113
ECE2 5083
EDN3 5061
CCL11 5058
CXCL1 5052
AGTR1 4704
PF4 4678
PRLHR 4628
RXFP1 4613
RXFP2 4606
CCL17 4258
PROK2 4078
EDN2 4061
QRFP 4053
PNOC 4051
CCL28 4004
CXCR1 3976
MLNR 3963
PROKR1 3879
SSTR2 3862
ACKR2 3692
GPR37 3394
NPW 3183
CCRL2 3060
CCL4 2930
CXCL13 2440
CCKBR 2398
XCL2 2225
TRHR 1877
RXFP3 1870
NPS 1761
SSTR5 1623
ANXA1 1369
CXCL12 1209
MC1R 1208
CCL25 1147
NMUR1 1006
BDKRB1 648
FPR2 615
CCR8 434
APP 410
XCL1 -64
NPFFR1 -125
BDKRB2 -290
GRP -477
EDNRB -527
F2RL1 -1064
KNG1 -1179
TACR2 -1193
CCR4 -1326
F2R -1436
PSAP -1493
OPRK1 -1574
AVPR1B -1702
MC3R -1725
UTS2 -1830
EDN1 -1981
ECE1 -2038
OXTR -2085
FPR3 -2117
F2RL2 -2141
CCR7 -2142
CXCR4 -2279
C3AR1 -2289
CCL20 -2331
MCHR2 -2497
CCR2 -3268
XCR1 -3294
NTSR1 -3360
CCL13 -3429
OPRM1 -3645
C3 -3747
GAL -3792
NPBWR2 -3985
GALR3 -4243
NPFFR2 -4391
NLN -4701
GPR37L1 -4720
OPRD1 -4993
HEBP1 -5020
MC4R -5099
NPSR1 -5120
CCL16 -5150
NTSR2 -5439
TAC3 -5652
NMBR -5773
CCL27 -5921
QRFPR -5949
INSL5 -6062
F2 -6090
TACR1 -6109
AGT -6262
GHRL -6514
NMB -7016
SST -7167
GPER1 -7252
NMS -7309
CXCL8 -7825
OXT -8167
INSL3 -8210
CORT -8397
CXCL9 -8525
KISS1 -8563
F2RL3 -8601
SSTR3 -8941
HCRTR1 -9023
CCR1 -9135
PROKR2 -9419
PROK1 -9625
CCR9 -10013
SAA1 -10073
CXCL10 -10155
PPY -10172
PMCH -10205
CCK -10232
SSTR4 -10364
PRLH -10395
HCRT -10543
CCL7 -10552
FPR1 -10573
CCR6 -10602
CXCR5 -10686
CX3CL1 -10719
CCKAR -10812
CCL21 -11021
CXCR6 -11069


REACTOME_SUMOYLATION_OF_TRANSCRIPTION_COFACTORS

REACTOME_SUMOYLATION_OF_TRANSCRIPTION_COFACTORS
645
set REACTOME_SUMOYLATION_OF_TRANSCRIPTION_COFACTORS
setSize 43
pANOVA 0.0106
s.dist -0.225
p.adjustANOVA 0.363



Top enriched genes

Top 20 genes
GeneID Gene Rank
PIAS4 -10499
SUMO2 -9534
SAFB -8962
ING2 -8788
PCGF2 -8767
DDX17 -8568
NCOA1 -8254
UBE2I -8199
PIAS3 -8143
TRIM28 -7984
EP300 -7432
NRIP1 -7302
NPM1 -7226
CBX2 -6709
UHRF2 -6587
CTBP1 -6303
BMI1 -5163
RING1 -5069
PHC1 -4881
MBD1 -3843

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PIAS4 -10499
SUMO2 -9534
SAFB -8962
ING2 -8788
PCGF2 -8767
DDX17 -8568
NCOA1 -8254
UBE2I -8199
PIAS3 -8143
TRIM28 -7984
EP300 -7432
NRIP1 -7302
NPM1 -7226
CBX2 -6709
UHRF2 -6587
CTBP1 -6303
BMI1 -5163
RING1 -5069
PHC1 -4881
MBD1 -3843
SUMO1 -3709
CBX8 -3634
PARK7 -3145
NCOA2 -2942
RNF2 -2837
CREBBP -2076
PHC3 -1890
TOPORS -1229
DDX5 -968
MRTFA -648
SCMH1 727
SIN3A 1355
SUMO3 1932
DAXX 2017
ZNF131 2925
HIPK2 3732
NCOR2 4797
ZNF350 5440
PIAS2 5865
PHC2 5912
PPARGC1A 6090
PIAS1 6280
CBX4 6386


REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_C_STRAND_OF_THE_TELOMERE

REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_C_STRAND_OF_THE_TELOMERE
253
set REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_C_STRAND_OF_THE_TELOMERE
setSize 19
pANOVA 0.0106
s.dist -0.338
p.adjustANOVA 0.363



Top enriched genes

Top 20 genes
GeneID Gene Rank
POLD2 -9835.0
POLD1 -9280.0
TERF1 -8662.0
LIG1 -8555.0
DNA2 -8554.0
POLD3 -7854.0
ACD -7311.5
TERF2 -6723.0
RPA1 -5995.0
POT1 -3264.0
PCNA -2763.0
RPA2 -2350.0
FEN1 -1752.0
RPA3 -1106.0
TINF2 -406.0
TERF2IP -95.0
POLD4 1139.0
WRN 2634.0
BLM 4939.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
POLD2 -9835.0
POLD1 -9280.0
TERF1 -8662.0
LIG1 -8555.0
DNA2 -8554.0
POLD3 -7854.0
ACD -7311.5
TERF2 -6723.0
RPA1 -5995.0
POT1 -3264.0
PCNA -2763.0
RPA2 -2350.0
FEN1 -1752.0
RPA3 -1106.0
TINF2 -406.0
TERF2IP -95.0
POLD4 1139.0
WRN 2634.0
BLM 4939.0


REACTOME_TRNA_MODIFICATION_IN_THE_NUCLEUS_AND_CYTOSOL

REACTOME_TRNA_MODIFICATION_IN_THE_NUCLEUS_AND_CYTOSOL
1035
set REACTOME_TRNA_MODIFICATION_IN_THE_NUCLEUS_AND_CYTOSOL
setSize 41
pANOVA 0.0107
s.dist -0.23
p.adjustANOVA 0.363



Top enriched genes

Top 20 genes
GeneID Gene Rank
CTU2 -9749
TRMT44 -9694
URM1 -9255
TRMT13 -9104
ADAT3 -9098
EPRS1 -8808
PUS7 -8524
TRDMT1 -8415
TPRKB -8127
TRIT1 -7372
WDR4 -7107
PUS3 -5883
PUS1 -5515
CDKAL1 -5484
TRMT1 -5316
THG1L -4879
QTRT1 -4827
TRMT61A -4468
TRMT9B -4423
LCMT2 -3602

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CTU2 -9749
TRMT44 -9694
URM1 -9255
TRMT13 -9104
ADAT3 -9098
EPRS1 -8808
PUS7 -8524
TRDMT1 -8415
TPRKB -8127
TRIT1 -7372
WDR4 -7107
PUS3 -5883
PUS1 -5515
CDKAL1 -5484
TRMT1 -5316
THG1L -4879
QTRT1 -4827
TRMT61A -4468
TRMT9B -4423
LCMT2 -3602
TRMT12 -3404
NSUN2 -3389
CTU1 -3113
ALKBH8 -2194
TRMT10A -1955
TYW1 -1540
QTRT2 -1286
TRMT11 -1201
THADA -507
NSUN6 769
TRMT6 853
METTL1 1626
DUS2 1784
OSGEP 2240
TYW5 2362
TRMT112 2720
TRMT5 2864
ADAT1 5246
TYW3 7255
TP53RK 7454
ADAT2 8327


REACTOME_REPRODUCTION

REACTOME_REPRODUCTION
114
set REACTOME_REPRODUCTION
setSize 136
pANOVA 0.0108
s.dist -0.127
p.adjustANOVA 0.363



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC3 -11072.0
ADAM21 -10909.0
PRDM9 -10877.0
H3C3 -10752.0
H3C6 -10696.0
SYCP1 -10277.0
H2BC26 -10276.0
H2AC7 -10188.5
H2BC7 -10188.5
CATSPER1 -10145.0
H2AC20 -10070.0
ADAM2 -9997.0
H2AC14 -9995.0
H3-4 -9817.0
H3C4 -9701.0
SYCP2 -9526.0
IZUMO2 -9212.0
SUN2 -9039.0
H2AC18 -9031.5
H2AC19 -9031.5

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC3 -11072.0
ADAM21 -10909.0
PRDM9 -10877.0
H3C3 -10752.0
H3C6 -10696.0
SYCP1 -10277.0
H2BC26 -10276.0
H2AC7 -10188.5
H2BC7 -10188.5
CATSPER1 -10145.0
H2AC20 -10070.0
ADAM2 -9997.0
H2AC14 -9995.0
H3-4 -9817.0
H3C4 -9701.0
SYCP2 -9526.0
IZUMO2 -9212.0
SUN2 -9039.0
H2AC18 -9031.5
H2AC19 -9031.5
TERF1 -8662.0
H3C1 -8260.0
H2BC14 -8236.0
UBE2I -8199.0
H2AC8 -8007.0
DMC1 -7964.0
ADAM30 -7948.0
CATSPERG -7897.0
H4C1 -7768.0
H2AX -7754.0
H2BC8 -7687.0
H2BC21 -7485.0
H3C11 -7455.0
TEX12 -7430.0
ACD -7311.5
MND1 -6876.0
TERF2 -6723.0
MSH5 -6034.0
RPA1 -5995.0
DIDO1 -5961.0
ADAM20 -5803.0
RAD51 -5528.0
ZP3 -5500.0
H4C4 -5408.0
H2BC1 -5406.0
NBN -5357.0
H4C9 -5033.0
CATSPER3 -4982.0
IZUMO4 -4948.0
H3-3B -4811.0
SUN1 -4675.0
SYCP3 -4192.0
H4C3 -3847.0
SMC3 -3481.0
SMC1B -3476.0
SYCE1 -3369.0
CATSPERB -3267.0
POT1 -3264.0
STAG1 -3209.0
RAD51C -3047.0
SYCE2 -3046.0
SYNE2 -2904.0
ATM -2840.0
H4C6 -2615.0
TOP3A -2386.0
RPA2 -2350.0
CDK4 -2328.0
H4C12 -2167.0
IZUMO1 -1959.0
H2BC12 -1743.0
ZP1 -1712.0
H4C16 -1250.0
SYNE1 -1177.0
H2AC4 -1132.0
RPA3 -1106.0
ATR -1075.0
H3C8 -1035.0
MLH3 -640.0
H4C11 -494.0
TINF2 -406.0
MSH4 -382.0
H2BC11 -106.0
TERF2IP -95.0
H2BC9 36.5
H3C7 36.5
MRE11 41.0
KCNU1 129.0
H2AZ2 203.0
BRCA1 231.0
CDK2 273.0
H4C5 481.0
PSMC3IP 1082.0
H2BC10 1117.0
SPAM1 1155.0
MLH1 1361.0
H2AJ 1474.0
IZUMO3 1550.0
ZP2 1790.0
H4C2 2031.0
HSPA2 2109.0
RAD50 2206.0
H4C13 2526.0
H2BC17 2583.0
B4GALT1 3375.0
REC8 3421.0
HVCN1 3890.0
H2BC15 3952.0
H2BC5 4154.0
H3C2 4334.0
LMNA 4450.0
BLM 4939.0
RAD21 5122.0
H2BC6 5880.0
CATSPER4 5956.0
H3-3A 6189.0
CATSPERD 6669.0
CATSPER2 6691.0
RBBP8 6725.0
CD9 6804.0
H4C8 6856.0
TEX15 6962.0
LMNB1 7206.0
SYCE3 7261.0
BRCA2 7348.0
STAG3 7541.0
H3C10 8230.0
SPO11 8429.0
OVGP1 8527.0
H2AZ1 8703.0
H2BC13 8750.0
FKBP6 9094.0
H2AC6 9114.0
H2BC4 9890.0
ZP4 9977.0
ACR 9997.0
H3C12 10509.0


REACTOME_DEFECTIVE_CSF2RB_CAUSES_SMDP5

REACTOME_DEFECTIVE_CSF2RB_CAUSES_SMDP5
1001
set REACTOME_DEFECTIVE_CSF2RB_CAUSES_SMDP5
setSize 7
pANOVA 0.0114
s.dist 0.552
p.adjustANOVA 0.37



Top enriched genes

Top 20 genes
GeneID Gene Rank
SFTPA1 10501
SFTPC 9484
CSF2RB 9411
SFTPD 7710
SFTA3 6048
SFTPA2 -1257
SFTPB -1261

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SFTPA1 10501
SFTPC 9484
CSF2RB 9411
SFTPD 7710
SFTA3 6048
SFTPA2 -1257
SFTPB -1261


Here is the session info with all the versions of packages used.

sessionInfo()
## R version 4.3.2 (2023-10-31)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.3 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3 
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so;  LAPACK version 3.10.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Etc/UTC
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.3.3                                      
##  [2] GGally_2.2.0                                       
##  [3] ggplot2_3.4.4                                      
##  [4] reshape2_1.4.4                                     
##  [5] gtools_3.9.5                                       
##  [6] tibble_3.2.1                                       
##  [7] dplyr_1.1.4                                        
##  [8] echarts4r_0.4.5                                    
##  [9] png_0.1-8                                          
## [10] gridExtra_2.3                                      
## [11] missMethyl_1.36.0                                  
## [12] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.1 
## [13] beeswarm_0.4.0                                     
## [14] kableExtra_1.3.4                                   
## [15] gplots_3.1.3                                       
## [16] mitch_1.15.0                                       
## [17] tictoc_1.2                                         
## [18] HGNChelper_0.8.1                                   
## [19] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [20] IlluminaHumanMethylation450kmanifest_0.4.0         
## [21] minfi_1.48.0                                       
## [22] bumphunter_1.44.0                                  
## [23] locfit_1.5-9.8                                     
## [24] iterators_1.0.14                                   
## [25] foreach_1.5.2                                      
## [26] Biostrings_2.70.1                                  
## [27] XVector_0.42.0                                     
## [28] SummarizedExperiment_1.32.0                        
## [29] Biobase_2.62.0                                     
## [30] MatrixGenerics_1.14.0                              
## [31] matrixStats_1.2.0                                  
## [32] GenomicRanges_1.54.1                               
## [33] GenomeInfoDb_1.38.2                                
## [34] IRanges_2.36.0                                     
## [35] S4Vectors_0.40.2                                   
## [36] BiocGenerics_0.48.1                                
## [37] eulerr_7.0.0                                       
## [38] limma_3.58.1                                       
## 
## loaded via a namespace (and not attached):
##   [1] splines_4.3.2             later_1.3.2              
##   [3] BiocIO_1.12.0             bitops_1.0-7             
##   [5] filelock_1.0.3            preprocessCore_1.64.0    
##   [7] XML_3.99-0.16             lifecycle_1.0.4          
##   [9] lattice_0.22-5            MASS_7.3-60              
##  [11] base64_2.0.1              scrime_1.3.5             
##  [13] magrittr_2.0.3            sass_0.4.8               
##  [15] rmarkdown_2.25            jquerylib_0.1.4          
##  [17] yaml_2.3.8                httpuv_1.6.13            
##  [19] doRNG_1.8.6               askpass_1.2.0            
##  [21] DBI_1.1.3                 RColorBrewer_1.1-3       
##  [23] abind_1.4-5               zlibbioc_1.48.0          
##  [25] rvest_1.0.3               quadprog_1.5-8           
##  [27] purrr_1.0.2               RCurl_1.98-1.13          
##  [29] rappdirs_0.3.3            GenomeInfoDbData_1.2.11  
##  [31] genefilter_1.84.0         annotate_1.80.0          
##  [33] svglite_2.1.3             DelayedMatrixStats_1.24.0
##  [35] codetools_0.2-19          DelayedArray_0.28.0      
##  [37] xml2_1.3.6                tidyselect_1.2.0         
##  [39] beanplot_1.3.1            BiocFileCache_2.10.1     
##  [41] webshot_0.5.5             illuminaio_0.44.0        
##  [43] GenomicAlignments_1.38.0  jsonlite_1.8.8           
##  [45] multtest_2.58.0           ellipsis_0.3.2           
##  [47] survival_3.5-7            systemfonts_1.0.5        
##  [49] tools_4.3.2               progress_1.2.3           
##  [51] Rcpp_1.0.11               glue_1.6.2               
##  [53] SparseArray_1.2.2         xfun_0.41                
##  [55] HDF5Array_1.30.0          withr_2.5.2              
##  [57] fastmap_1.1.1             rhdf5filters_1.14.1      
##  [59] fansi_1.0.6               openssl_2.1.1            
##  [61] caTools_1.18.2            digest_0.6.33            
##  [63] R6_2.5.1                  mime_0.12                
##  [65] colorspace_2.1-0          biomaRt_2.58.0           
##  [67] RSQLite_2.3.4             utf8_1.2.4               
##  [69] tidyr_1.3.0               generics_0.1.3           
##  [71] data.table_1.14.10        rtracklayer_1.62.0       
##  [73] prettyunits_1.2.0         httr_1.4.7               
##  [75] htmlwidgets_1.6.4         S4Arrays_1.2.0           
##  [77] ggstats_0.5.1             pkgconfig_2.0.3          
##  [79] gtable_0.3.4              blob_1.2.4               
##  [81] siggenes_1.76.0           htmltools_0.5.7          
##  [83] scales_1.3.0              rstudioapi_0.15.0        
##  [85] knitr_1.45                tzdb_0.4.0               
##  [87] rjson_0.2.21              nlme_3.1-163             
##  [89] curl_5.2.0                org.Hs.eg.db_3.18.0      
##  [91] cachem_1.0.8              rhdf5_2.46.1             
##  [93] stringr_1.5.1             KernSmooth_2.23-22       
##  [95] AnnotationDbi_1.64.1      restfulr_0.0.15          
##  [97] GEOquery_2.70.0           pillar_1.9.0             
##  [99] grid_4.3.2                reshape_0.8.9            
## [101] vctrs_0.6.5               promises_1.2.1           
## [103] dbplyr_2.4.0              xtable_1.8-4             
## [105] evaluate_0.23             readr_2.1.4              
## [107] GenomicFeatures_1.54.1    cli_3.6.2                
## [109] compiler_4.3.2            Rsamtools_2.18.0         
## [111] rlang_1.1.2               crayon_1.5.2             
## [113] rngtools_1.5.2            nor1mix_1.3-2            
## [115] mclust_6.0.1              plyr_1.8.9               
## [117] stringi_1.8.3             viridisLite_0.4.2        
## [119] BiocParallel_1.36.0       munsell_0.5.0            
## [121] Matrix_1.6-1.1            hms_1.1.3                
## [123] sparseMatrixStats_1.14.0  bit64_4.0.5              
## [125] Rhdf5lib_1.24.1           KEGGREST_1.42.0          
## [127] statmod_1.5.0             shiny_1.8.0              
## [129] highr_0.10                memoise_2.0.1            
## [131] bslib_0.6.1               bit_4.0.5

END of report