Mitch Report
Antony Kaspi & Mark Ziemann
date generated: 2024-01-18
Background
Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch
Input profiles
Here is the first few lines of the input profile.
| x | |
|---|---|
| A1BG | 0.0087595 |
| A1BG-AS1 | 0.0116844 |
| A1CF | 0.0031139 |
| A2M | -0.0006029 |
| A2M-AS1 | -0.0099503 |
| A2ML1 | 0.0029536 |
Here are some metrics about the input data profile:
| Profile metrics | |
|---|---|
| num_genesets | 1654 |
| num_genes_in_profile | 22007 |
| duplicated_genes_present | 0 |
| num_profile_genes_in_sets | 10383 |
| num_profile_genes_not_in_sets | 11624 |
Here is a plot of the input profiles. Note the dynamic ranges.
Here is the contour plot of the profile including all detected genes.
Input genesets
Here are some metrics about the gene sets used:
GMT file of genesets: c2.cp.reactome.v2023.1.Hs.symbols.gmt| Gene sets metrics | |
|---|---|
| num_genesets | 1654 |
| num_genesets_excluded | 365 |
| num_genesets_included | 1289 |
Differential pathway expression
Interactive enrichment scatterplot
Significance is calculated by -log10(p-value). All points shown are
FDR<0.05.
Significance is calculated by -log10(p-value). Top N sets shown
irrespective of FDR.
Results table
Top N= 50 gene sets
## Warning in kable_styling(., "hover", full_width = FALSE): Please specify format
## in kable. kableExtra can customize either HTML or LaTeX outputs. See
## https://haozhu233.github.io/kableExtra/ for details.| set | setSize | pANOVA | s.dist | p.adjustANOVA |
|---|---|---|---|---|
| REACTOME NEUTROPHIL DEGRANULATION | 460 | 3.99e-07 | -0.1380 | 0.000655 |
| REACTOME KERATINIZATION | 210 | 9.49e-07 | 0.1960 | 0.000779 |
| REACTOME SENSORY PERCEPTION | 555 | 8.93e-06 | 0.1100 | 0.004890 |
| REACTOME FORMATION OF THE CORNIFIED ENVELOPE | 125 | 3.49e-05 | 0.2140 | 0.014300 |
| REACTOME GENERATION OF SECOND MESSENGER MOLECULES | 30 | 1.15e-03 | 0.3430 | 0.377000 |
| REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION | 10 | 1.50e-03 | -0.5800 | 0.412000 |
| REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH | 62 | 1.79e-03 | 0.2290 | 0.421000 |
| REACTOME COSTIMULATION BY THE CD28 FAMILY | 64 | 2.45e-03 | 0.2190 | 0.477000 |
| REACTOME TYPE I HEMIDESMOSOME ASSEMBLY | 11 | 2.61e-03 | 0.5240 | 0.477000 |
| REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS | 16 | 3.54e-03 | 0.4210 | 0.581000 |
| REACTOME TCR SIGNALING | 113 | 4.90e-03 | 0.1530 | 0.715000 |
| REACTOME PD 1 SIGNALING | 21 | 5.22e-03 | 0.3520 | 0.715000 |
| REACTOME VISUAL PHOTOTRANSDUCTION | 93 | 7.13e-03 | 0.1610 | 0.775000 |
| REACTOME GLUCOCORTICOID BIOSYNTHESIS | 10 | 7.24e-03 | 0.4900 | 0.775000 |
| REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES | 34 | 7.52e-03 | -0.2650 | 0.775000 |
| REACTOME CARNITINE METABOLISM | 13 | 7.75e-03 | -0.4260 | 0.775000 |
| REACTOME DEFECTIVE GALNT3 CAUSES HFTC | 16 | 8.05e-03 | 0.3830 | 0.775000 |
| REACTOME OLFACTORY SIGNALING PATHWAY | 348 | 8.67e-03 | 0.0819 | 0.775000 |
| REACTOME P75NTR REGULATES AXONOGENESIS | 9 | 9.36e-03 | 0.5000 | 0.775000 |
| REACTOME DISSOLUTION OF FIBRIN CLOT | 13 | 9.69e-03 | -0.4140 | 0.775000 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES | 8 | 9.91e-03 | -0.5270 | 0.775000 |
| REACTOME EICOSANOID LIGAND BINDING RECEPTORS | 14 | 1.04e-02 | -0.3950 | 0.777000 |
| REACTOME SYNTHESIS OF LIPOXINS LX | 6 | 1.12e-02 | -0.5980 | 0.798000 |
| REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4 | 33 | 1.23e-02 | 0.2520 | 0.798000 |
| REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS | 53 | 1.27e-02 | -0.1980 | 0.798000 |
| REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | 11 | 1.30e-02 | -0.4330 | 0.798000 |
| REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS | 6 | 1.31e-02 | -0.5850 | 0.798000 |
| REACTOME RMTS METHYLATE HISTONE ARGININES | 72 | 1.41e-02 | 0.1670 | 0.825000 |
| REACTOME INTERLEUKIN 36 PATHWAY | 7 | 1.55e-02 | 0.5280 | 0.876000 |
| REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION | 11 | 1.72e-02 | -0.4150 | 0.944000 |
| REACTOME SURFACTANT METABOLISM | 28 | 1.88e-02 | 0.2570 | 0.957000 |
| REACTOME GLUTAMATE AND GLUTAMINE METABOLISM | 13 | 1.88e-02 | -0.3760 | 0.957000 |
| REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS | 29 | 1.92e-02 | -0.2510 | 0.957000 |
| REACTOME ORGANIC ANION TRANSPORT | 5 | 2.02e-02 | 0.6000 | 0.976000 |
| REACTOME CREATINE METABOLISM | 9 | 2.10e-02 | -0.4440 | 0.977000 |
| REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | 89 | 2.18e-02 | 0.1410 | 0.977000 |
| REACTOME RNA POLYMERASE I TRANSCRIPTION | 102 | 2.22e-02 | 0.1310 | 0.977000 |
| REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX | 13 | 2.40e-02 | -0.3620 | 0.977000 |
| REACTOME BIOTIN TRANSPORT AND METABOLISM | 10 | 2.41e-02 | -0.4120 | 0.977000 |
| REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES | 21 | 2.45e-02 | 0.2830 | 0.977000 |
| REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS | 17 | 2.51e-02 | 0.3140 | 0.977000 |
| REACTOME COLLAGEN CHAIN TRIMERIZATION | 42 | 2.62e-02 | 0.1980 | 0.977000 |
| REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION | 26 | 2.70e-02 | -0.2510 | 0.977000 |
| REACTOME INNATE IMMUNE SYSTEM | 1002 | 2.86e-02 | -0.0409 | 0.977000 |
| REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE | 71 | 2.94e-02 | -0.1500 | 0.977000 |
| REACTOME NCAM1 INTERACTIONS | 41 | 2.97e-02 | 0.1960 | 0.977000 |
| REACTOME DEVELOPMENTAL BIOLOGY | 1115 | 3.15e-02 | 0.0382 | 0.977000 |
| REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS | 8 | 3.21e-02 | -0.4370 | 0.977000 |
| REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS | 19 | 3.28e-02 | -0.2830 | 0.977000 |
| REACTOME BILE ACID AND BILE SALT METABOLISM | 45 | 3.31e-02 | 0.1840 | 0.977000 |
Results (complete table)
Click HERE to show results for all gene sets
| set | setSize | pANOVA | s.dist | p.adjustANOVA |
|---|---|---|---|---|
| REACTOME NEUTROPHIL DEGRANULATION | 460 | 3.99e-07 | -1.38e-01 | 0.000655 |
| REACTOME KERATINIZATION | 210 | 9.49e-07 | 1.96e-01 | 0.000779 |
| REACTOME SENSORY PERCEPTION | 555 | 8.93e-06 | 1.10e-01 | 0.004890 |
| REACTOME FORMATION OF THE CORNIFIED ENVELOPE | 125 | 3.49e-05 | 2.14e-01 | 0.014300 |
| REACTOME GENERATION OF SECOND MESSENGER MOLECULES | 30 | 1.15e-03 | 3.43e-01 | 0.377000 |
| REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION | 10 | 1.50e-03 | -5.80e-01 | 0.412000 |
| REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH | 62 | 1.79e-03 | 2.29e-01 | 0.421000 |
| REACTOME COSTIMULATION BY THE CD28 FAMILY | 64 | 2.45e-03 | 2.19e-01 | 0.477000 |
| REACTOME TYPE I HEMIDESMOSOME ASSEMBLY | 11 | 2.61e-03 | 5.24e-01 | 0.477000 |
| REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS | 16 | 3.54e-03 | 4.21e-01 | 0.581000 |
| REACTOME TCR SIGNALING | 113 | 4.90e-03 | 1.53e-01 | 0.715000 |
| REACTOME PD 1 SIGNALING | 21 | 5.22e-03 | 3.52e-01 | 0.715000 |
| REACTOME VISUAL PHOTOTRANSDUCTION | 93 | 7.13e-03 | 1.61e-01 | 0.775000 |
| REACTOME GLUCOCORTICOID BIOSYNTHESIS | 10 | 7.24e-03 | 4.90e-01 | 0.775000 |
| REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES | 34 | 7.52e-03 | -2.65e-01 | 0.775000 |
| REACTOME CARNITINE METABOLISM | 13 | 7.75e-03 | -4.26e-01 | 0.775000 |
| REACTOME DEFECTIVE GALNT3 CAUSES HFTC | 16 | 8.05e-03 | 3.83e-01 | 0.775000 |
| REACTOME OLFACTORY SIGNALING PATHWAY | 348 | 8.67e-03 | 8.19e-02 | 0.775000 |
| REACTOME P75NTR REGULATES AXONOGENESIS | 9 | 9.36e-03 | 5.00e-01 | 0.775000 |
| REACTOME DISSOLUTION OF FIBRIN CLOT | 13 | 9.69e-03 | -4.14e-01 | 0.775000 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES | 8 | 9.91e-03 | -5.27e-01 | 0.775000 |
| REACTOME EICOSANOID LIGAND BINDING RECEPTORS | 14 | 1.04e-02 | -3.95e-01 | 0.777000 |
| REACTOME SYNTHESIS OF LIPOXINS LX | 6 | 1.12e-02 | -5.98e-01 | 0.798000 |
| REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4 | 33 | 1.23e-02 | 2.52e-01 | 0.798000 |
| REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS | 53 | 1.27e-02 | -1.98e-01 | 0.798000 |
| REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | 11 | 1.30e-02 | -4.33e-01 | 0.798000 |
| REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS | 6 | 1.31e-02 | -5.85e-01 | 0.798000 |
| REACTOME RMTS METHYLATE HISTONE ARGININES | 72 | 1.41e-02 | 1.67e-01 | 0.825000 |
| REACTOME INTERLEUKIN 36 PATHWAY | 7 | 1.55e-02 | 5.28e-01 | 0.876000 |
| REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION | 11 | 1.72e-02 | -4.15e-01 | 0.944000 |
| REACTOME SURFACTANT METABOLISM | 28 | 1.88e-02 | 2.57e-01 | 0.957000 |
| REACTOME GLUTAMATE AND GLUTAMINE METABOLISM | 13 | 1.88e-02 | -3.76e-01 | 0.957000 |
| REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS | 29 | 1.92e-02 | -2.51e-01 | 0.957000 |
| REACTOME ORGANIC ANION TRANSPORT | 5 | 2.02e-02 | 6.00e-01 | 0.976000 |
| REACTOME CREATINE METABOLISM | 9 | 2.10e-02 | -4.44e-01 | 0.977000 |
| REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | 89 | 2.18e-02 | 1.41e-01 | 0.977000 |
| REACTOME RNA POLYMERASE I TRANSCRIPTION | 102 | 2.22e-02 | 1.31e-01 | 0.977000 |
| REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX | 13 | 2.40e-02 | -3.62e-01 | 0.977000 |
| REACTOME BIOTIN TRANSPORT AND METABOLISM | 10 | 2.41e-02 | -4.12e-01 | 0.977000 |
| REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES | 21 | 2.45e-02 | 2.83e-01 | 0.977000 |
| REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS | 17 | 2.51e-02 | 3.14e-01 | 0.977000 |
| REACTOME COLLAGEN CHAIN TRIMERIZATION | 42 | 2.62e-02 | 1.98e-01 | 0.977000 |
| REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION | 26 | 2.70e-02 | -2.51e-01 | 0.977000 |
| REACTOME INNATE IMMUNE SYSTEM | 1002 | 2.86e-02 | -4.09e-02 | 0.977000 |
| REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE | 71 | 2.94e-02 | -1.50e-01 | 0.977000 |
| REACTOME NCAM1 INTERACTIONS | 41 | 2.97e-02 | 1.96e-01 | 0.977000 |
| REACTOME DEVELOPMENTAL BIOLOGY | 1115 | 3.15e-02 | 3.82e-02 | 0.977000 |
| REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS | 8 | 3.21e-02 | -4.37e-01 | 0.977000 |
| REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS | 19 | 3.28e-02 | -2.83e-01 | 0.977000 |
| REACTOME BILE ACID AND BILE SALT METABOLISM | 45 | 3.31e-02 | 1.84e-01 | 0.977000 |
| REACTOME GASTRULATION | 49 | 3.40e-02 | -1.75e-01 | 0.977000 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS | 12 | 3.43e-02 | -3.53e-01 | 0.977000 |
| REACTOME SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA | 52 | 3.61e-02 | 1.68e-01 | 0.977000 |
| REACTOME NRAGE SIGNALS DEATH THROUGH JNK | 53 | 3.64e-02 | 1.66e-01 | 0.977000 |
| REACTOME NOD1 2 SIGNALING PATHWAY | 33 | 3.70e-02 | -2.10e-01 | 0.977000 |
| REACTOME MTOR SIGNALLING | 40 | 3.86e-02 | -1.89e-01 | 0.977000 |
| REACTOME INTEGRATION OF PROVIRUS | 9 | 4.01e-02 | -3.95e-01 | 0.977000 |
| REACTOME MITOCHONDRIAL TRANSLATION | 93 | 4.09e-02 | 1.23e-01 | 0.977000 |
| REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI | 26 | 4.20e-02 | -2.30e-01 | 0.977000 |
| REACTOME SIGNALING BY INSULIN RECEPTOR | 80 | 4.21e-02 | 1.31e-01 | 0.977000 |
| REACTOME DEFECTIVE CHST6 CAUSES MCDC1 | 8 | 4.29e-02 | 4.13e-01 | 0.977000 |
| REACTOME ADHERENS JUNCTIONS INTERACTIONS | 33 | 4.34e-02 | -2.03e-01 | 0.977000 |
| REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE | 35 | 4.40e-02 | -1.97e-01 | 0.977000 |
| REACTOME THE NLRP3 INFLAMMASOME | 16 | 4.51e-02 | -2.89e-01 | 0.977000 |
| REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK | 28 | 4.59e-02 | -2.18e-01 | 0.977000 |
| REACTOME TP53 REGULATES METABOLIC GENES | 81 | 4.67e-02 | -1.28e-01 | 0.977000 |
| REACTOME SENSORY PROCESSING OF SOUND | 72 | 4.77e-02 | 1.35e-01 | 0.977000 |
| REACTOME CD28 DEPENDENT VAV1 PATHWAY | 11 | 4.81e-02 | 3.44e-01 | 0.977000 |
| REACTOME PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS | 8 | 5.02e-02 | -4.00e-01 | 0.977000 |
| REACTOME ACTIVATION OF AMPK DOWNSTREAM OF NMDARS | 28 | 5.10e-02 | -2.13e-01 | 0.977000 |
| REACTOME MET PROMOTES CELL MOTILITY | 41 | 5.19e-02 | 1.75e-01 | 0.977000 |
| REACTOME RHO GTPASES ACTIVATE WASPS AND WAVES | 34 | 5.24e-02 | 1.92e-01 | 0.977000 |
| REACTOME HOMOLOGY DIRECTED REPAIR | 132 | 5.36e-02 | -9.73e-02 | 0.977000 |
| REACTOME KILLING MECHANISMS | 11 | 5.39e-02 | 3.36e-01 | 0.977000 |
| REACTOME INTERLEUKIN 1 PROCESSING | 9 | 5.40e-02 | -3.71e-01 | 0.977000 |
| REACTOME INSULIN RECEPTOR SIGNALLING CASCADE | 53 | 5.46e-02 | 1.53e-01 | 0.977000 |
| REACTOME AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY | 8 | 5.49e-02 | -3.92e-01 | 0.977000 |
| REACTOME IRF3 MEDIATED INDUCTION OF TYPE I IFN | 13 | 5.58e-02 | -3.06e-01 | 0.977000 |
| REACTOME CREATION OF C4 AND C2 ACTIVATORS | 14 | 5.58e-02 | 2.95e-01 | 0.977000 |
| REACTOME PLASMA LIPOPROTEIN REMODELING | 33 | 5.66e-02 | 1.92e-01 | 0.977000 |
| REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | 14 | 5.70e-02 | 2.94e-01 | 0.977000 |
| REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES | 18 | 5.71e-02 | 2.59e-01 | 0.977000 |
| REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | 23 | 5.80e-02 | 2.28e-01 | 0.977000 |
| REACTOME RAF INDEPENDENT MAPK1 3 ACTIVATION | 22 | 5.85e-02 | 2.33e-01 | 0.977000 |
| REACTOME CTLA4 INHIBITORY SIGNALING | 21 | 5.96e-02 | 2.37e-01 | 0.977000 |
| REACTOME HIV TRANSCRIPTION ELONGATION | 42 | 6.01e-02 | 1.68e-01 | 0.977000 |
| REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION | 98 | 6.16e-02 | 1.09e-01 | 0.977000 |
| REACTOME UBIQUINOL BIOSYNTHESIS | 8 | 6.20e-02 | -3.81e-01 | 0.977000 |
| REACTOME MAPK FAMILY SIGNALING CASCADES | 314 | 6.20e-02 | 6.12e-02 | 0.977000 |
| REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | 91 | 6.26e-02 | -1.13e-01 | 0.977000 |
| REACTOME HDR THROUGH HOMOLOGOUS RECOMBINATION HRR | 66 | 6.41e-02 | -1.32e-01 | 0.977000 |
| REACTOME SIGNALING BY NOTCH | 234 | 6.44e-02 | 7.02e-02 | 0.977000 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES | 61 | 6.44e-02 | 1.37e-01 | 0.977000 |
| REACTOME ASPARAGINE N LINKED GLYCOSYLATION | 299 | 6.49e-02 | -6.21e-02 | 0.977000 |
| REACTOME REPRODUCTION | 136 | 6.51e-02 | 9.16e-02 | 0.977000 |
| REACTOME TRANSPORT OF ORGANIC ANIONS | 10 | 6.54e-02 | 3.36e-01 | 0.977000 |
| REACTOME GLUTATHIONE CONJUGATION | 33 | 6.57e-02 | -1.85e-01 | 0.977000 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES | 43 | 6.59e-02 | -1.62e-01 | 0.977000 |
| REACTOME RRNA PROCESSING | 192 | 6.63e-02 | 7.68e-02 | 0.977000 |
| REACTOME INTEGRIN CELL SURFACE INTERACTIONS | 83 | 6.68e-02 | 1.16e-01 | 0.977000 |
| REACTOME VLDL CLEARANCE | 6 | 7.05e-02 | 4.26e-01 | 0.977000 |
| REACTOME DEFECTS IN BIOTIN BTN METABOLISM | 8 | 7.08e-02 | -3.69e-01 | 0.977000 |
| REACTOME NERVOUS SYSTEM DEVELOPMENT | 552 | 7.12e-02 | 4.49e-02 | 0.977000 |
| REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE | 69 | 7.15e-02 | 1.25e-01 | 0.977000 |
| REACTOME UCH PROTEINASES | 99 | 7.17e-02 | 1.05e-01 | 0.977000 |
| REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION | 45 | 7.18e-02 | 1.55e-01 | 0.977000 |
| REACTOME COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES | 65 | 7.31e-02 | 1.29e-01 | 0.977000 |
| REACTOME CHYLOMICRON CLEARANCE | 5 | 7.33e-02 | 4.63e-01 | 0.977000 |
| REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | 11 | 7.33e-02 | 3.12e-01 | 0.977000 |
| REACTOME HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR IN THE PRESENCE OF LIGAND | 55 | 7.33e-02 | -1.40e-01 | 0.977000 |
| REACTOME PARASITE INFECTION | 57 | 7.41e-02 | 1.37e-01 | 0.977000 |
| REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION | 68 | 7.45e-02 | 1.25e-01 | 0.977000 |
| REACTOME RECYCLING OF BILE ACIDS AND SALTS | 18 | 7.52e-02 | 2.42e-01 | 0.977000 |
| REACTOME PHASE II CONJUGATION OF COMPOUNDS | 102 | 7.67e-02 | -1.01e-01 | 0.977000 |
| REACTOME FIBRONECTIN MATRIX FORMATION | 6 | 7.68e-02 | -4.17e-01 | 0.977000 |
| REACTOME ACTIVATION OF SMO | 18 | 7.69e-02 | -2.41e-01 | 0.977000 |
| REACTOME RNA POLYMERASE II TRANSCRIPTION | 1336 | 7.72e-02 | -2.88e-02 | 0.977000 |
| REACTOME N GLYCAN ANTENNAE ELONGATION | 15 | 7.77e-02 | -2.63e-01 | 0.977000 |
| REACTOME RHO GTPASES ACTIVATE IQGAPS | 31 | 7.79e-02 | -1.83e-01 | 0.977000 |
| REACTOME G ALPHA 12 13 SIGNALLING EVENTS | 74 | 7.85e-02 | 1.18e-01 | 0.977000 |
| REACTOME ACYL CHAIN REMODELLING OF PG | 18 | 7.87e-02 | 2.39e-01 | 0.977000 |
| REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS | 100 | 8.17e-02 | 1.01e-01 | 0.977000 |
| REACTOME PROPIONYL COA CATABOLISM | 5 | 8.18e-02 | -4.49e-01 | 0.977000 |
| REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX | 85 | 8.19e-02 | 1.09e-01 | 0.977000 |
| REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND | 21 | 8.25e-02 | 2.19e-01 | 0.977000 |
| REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE | 63 | 8.37e-02 | 1.26e-01 | 0.977000 |
| REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION | 23 | 8.57e-02 | 2.07e-01 | 0.977000 |
| REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3 | 59 | 8.75e-02 | 1.29e-01 | 0.977000 |
| REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | 183 | 8.76e-02 | -7.32e-02 | 0.977000 |
| REACTOME GLYCOSAMINOGLYCAN METABOLISM | 118 | 8.77e-02 | -9.10e-02 | 0.977000 |
| REACTOME FORMATION OF LATERAL PLATE MESODERM | 5 | 8.79e-02 | -4.41e-01 | 0.977000 |
| REACTOME MET ACTIVATES PTK2 SIGNALING | 30 | 8.83e-02 | 1.80e-01 | 0.977000 |
| REACTOME SENSORY PERCEPTION OF SALTY TASTE | 6 | 8.92e-02 | 4.01e-01 | 0.977000 |
| REACTOME METABOLISM OF RNA | 675 | 9.08e-02 | 3.82e-02 | 0.977000 |
| REACTOME SIGNALING BY FGFR2 IN DISEASE | 42 | 9.24e-02 | 1.50e-01 | 0.977000 |
| REACTOME LIGAND RECEPTOR INTERACTIONS | 8 | 9.41e-02 | -3.42e-01 | 0.977000 |
| REACTOME INFLAMMASOMES | 21 | 9.47e-02 | -2.11e-01 | 0.977000 |
| REACTOME SENSORY PERCEPTION OF TASTE | 47 | 9.64e-02 | 1.40e-01 | 0.977000 |
| REACTOME RNA POLYMERASE I PROMOTER ESCAPE | 83 | 9.66e-02 | 1.06e-01 | 0.977000 |
| REACTOME SYNTHESIS OF UDP N ACETYL GLUCOSAMINE | 7 | 9.69e-02 | -3.62e-01 | 0.977000 |
| REACTOME CD28 CO STIMULATION | 32 | 9.74e-02 | 1.69e-01 | 0.977000 |
| REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL | 13 | 9.75e-02 | 2.65e-01 | 0.977000 |
| REACTOME SUMO IS TRANSFERRED FROM E1 TO E2 UBE2I UBC9 | 7 | 9.80e-02 | 3.61e-01 | 0.977000 |
| REACTOME ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS | 10 | 9.81e-02 | 3.02e-01 | 0.977000 |
| REACTOME SIGNALING BY NODAL | 20 | 9.81e-02 | 2.14e-01 | 0.977000 |
| REACTOME METABOLISM OF INGESTED SEMET SEC MESEC INTO H2SE | 7 | 9.83e-02 | -3.61e-01 | 0.977000 |
| REACTOME DEATH RECEPTOR SIGNALING | 143 | 9.90e-02 | 7.99e-02 | 0.977000 |
| REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER | 18 | 9.93e-02 | -2.24e-01 | 0.977000 |
| REACTOME SIGNALING BY FGFR | 85 | 9.93e-02 | 1.03e-01 | 0.977000 |
| REACTOME HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS | 7 | 9.97e-02 | 3.59e-01 | 0.977000 |
| REACTOME PHOSPHORYLATION OF EMI1 | 6 | 9.98e-02 | -3.88e-01 | 0.977000 |
| REACTOME EUKARYOTIC TRANSLATION ELONGATION | 87 | 1.00e-01 | 1.02e-01 | 0.977000 |
| REACTOME DAP12 SIGNALING | 27 | 1.00e-01 | 1.83e-01 | 0.977000 |
| REACTOME IRS MEDIATED SIGNALLING | 47 | 1.02e-01 | 1.38e-01 | 0.977000 |
| REACTOME CELLULAR RESPONSE TO STARVATION | 147 | 1.02e-01 | 7.82e-02 | 0.977000 |
| REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES | 15 | 1.03e-01 | 2.43e-01 | 0.977000 |
| REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION | 1356 | 1.03e-01 | -2.64e-02 | 0.977000 |
| REACTOME CYTOSOLIC TRNA AMINOACYLATION | 22 | 1.04e-01 | -2.00e-01 | 0.977000 |
| REACTOME RELAXIN RECEPTORS | 8 | 1.04e-01 | -3.32e-01 | 0.977000 |
| REACTOME HIV ELONGATION ARREST AND RECOVERY | 33 | 1.04e-01 | 1.64e-01 | 0.977000 |
| REACTOME EARLY PHASE OF HIV LIFE CYCLE | 14 | 1.05e-01 | -2.50e-01 | 0.977000 |
| REACTOME MINERALOCORTICOID BIOSYNTHESIS | 6 | 1.05e-01 | 3.82e-01 | 0.977000 |
| REACTOME PEROXISOMAL LIPID METABOLISM | 28 | 1.05e-01 | 1.77e-01 | 0.977000 |
| REACTOME SIGNALING BY ROBO RECEPTORS | 206 | 1.06e-01 | 6.53e-02 | 0.977000 |
| REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS | 312 | 1.08e-01 | -5.30e-02 | 0.977000 |
| REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE | 277 | 1.08e-01 | -5.61e-02 | 0.977000 |
| REACTOME GLUCAGON TYPE LIGAND RECEPTORS | 32 | 1.09e-01 | 1.64e-01 | 0.977000 |
| REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX | 32 | 1.10e-01 | 1.63e-01 | 0.977000 |
| REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS | 14 | 1.11e-01 | 2.46e-01 | 0.977000 |
| REACTOME NUCLEOTIDE CATABOLISM | 35 | 1.11e-01 | -1.56e-01 | 0.977000 |
| REACTOME DUAL INCISION IN GG NER | 39 | 1.12e-01 | -1.47e-01 | 0.977000 |
| REACTOME LYSOSOME VESICLE BIOGENESIS | 33 | 1.12e-01 | -1.60e-01 | 0.977000 |
| REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | 12 | 1.13e-01 | -2.64e-01 | 0.977000 |
| REACTOME MUCOPOLYSACCHARIDOSES | 10 | 1.15e-01 | -2.88e-01 | 0.977000 |
| REACTOME CLEC7A INFLAMMASOME PATHWAY | 6 | 1.16e-01 | -3.71e-01 | 0.977000 |
| REACTOME MICRORNA MIRNA BIOGENESIS | 25 | 1.16e-01 | 1.82e-01 | 0.977000 |
| REACTOME HDACS DEACETYLATE HISTONES | 85 | 1.17e-01 | 9.84e-02 | 0.977000 |
| REACTOME PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE | 74 | 1.17e-01 | 1.05e-01 | 0.977000 |
| REACTOME PERK REGULATES GENE EXPRESSION | 31 | 1.17e-01 | 1.63e-01 | 0.977000 |
| REACTOME IRAK4 DEFICIENCY TLR2 4 | 17 | 1.19e-01 | 2.18e-01 | 0.977000 |
| REACTOME REGULATION OF LIPID METABOLISM BY PPARALPHA | 115 | 1.19e-01 | -8.41e-02 | 0.977000 |
| REACTOME GENE SILENCING BY RNA | 133 | 1.20e-01 | 7.81e-02 | 0.977000 |
| REACTOME EPHRIN SIGNALING | 17 | 1.20e-01 | 2.18e-01 | 0.977000 |
| REACTOME TRANSLATION | 278 | 1.20e-01 | 5.41e-02 | 0.977000 |
| REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | 11 | 1.21e-01 | 2.70e-01 | 0.977000 |
| REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS | 18 | 1.21e-01 | -2.11e-01 | 0.977000 |
| REACTOME PROCESSING OF SMDT1 | 16 | 1.24e-01 | -2.22e-01 | 0.977000 |
| REACTOME MRNA SPLICING MINOR PATHWAY | 49 | 1.25e-01 | 1.27e-01 | 0.977000 |
| REACTOME DECTIN 2 FAMILY | 26 | 1.25e-01 | 1.74e-01 | 0.977000 |
| REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY | 94 | 1.25e-01 | 9.15e-02 | 0.977000 |
| REACTOME FCERI MEDIATED MAPK ACTIVATION | 32 | 1.28e-01 | 1.56e-01 | 0.977000 |
| REACTOME MAPK6 MAPK4 SIGNALING | 91 | 1.28e-01 | 9.24e-02 | 0.977000 |
| REACTOME INOSITOL PHOSPHATE METABOLISM | 45 | 1.28e-01 | 1.31e-01 | 0.977000 |
| REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | 30 | 1.28e-01 | 1.60e-01 | 0.977000 |
| REACTOME CELLULAR RESPONSE TO HYPOXIA | 74 | 1.28e-01 | 1.02e-01 | 0.977000 |
| REACTOME NEGATIVE REGULATION OF ACTIVITY OF TFAP2 AP 2 FAMILY TRANSCRIPTION FACTORS | 10 | 1.28e-01 | 2.78e-01 | 0.977000 |
| REACTOME SUMOYLATION OF IMMUNE RESPONSE PROTEINS | 10 | 1.29e-01 | 2.77e-01 | 0.977000 |
| REACTOME DNA DOUBLE STRAND BREAK REPAIR | 162 | 1.30e-01 | -6.90e-02 | 0.977000 |
| REACTOME MITOCHONDRIAL CALCIUM ION TRANSPORT | 23 | 1.30e-01 | -1.82e-01 | 0.977000 |
| REACTOME SIGNALING BY FGFR2 IIIA TM | 19 | 1.31e-01 | 2.00e-01 | 0.977000 |
| REACTOME 2 LTR CIRCLE FORMATION | 7 | 1.33e-01 | -3.28e-01 | 0.977000 |
| REACTOME RAB GERANYLGERANYLATION | 57 | 1.33e-01 | -1.15e-01 | 0.977000 |
| REACTOME ERBB2 REGULATES CELL MOTILITY | 15 | 1.33e-01 | -2.24e-01 | 0.977000 |
| REACTOME GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION | 30 | 1.34e-01 | -1.58e-01 | 0.977000 |
| REACTOME PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1 | 9 | 1.34e-01 | 2.88e-01 | 0.977000 |
| REACTOME G2 M DNA DAMAGE CHECKPOINT | 90 | 1.35e-01 | -9.13e-02 | 0.977000 |
| REACTOME MEMBRANE TRAFFICKING | 603 | 1.35e-01 | -3.56e-02 | 0.977000 |
| REACTOME ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT | 23 | 1.36e-01 | 1.79e-01 | 0.977000 |
| REACTOME ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES | 59 | 1.37e-01 | 1.12e-01 | 0.977000 |
| REACTOME CHROMATIN MODIFYING ENZYMES | 252 | 1.37e-01 | 5.44e-02 | 0.977000 |
| REACTOME HUR ELAVL1 BINDS AND STABILIZES MRNA | 8 | 1.37e-01 | -3.04e-01 | 0.977000 |
| REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES | 37 | 1.37e-01 | -1.41e-01 | 0.977000 |
| REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS | 161 | 1.38e-01 | 6.78e-02 | 0.977000 |
| REACTOME SUMOYLATION OF TRANSCRIPTION FACTORS | 20 | 1.38e-01 | 1.92e-01 | 0.977000 |
| REACTOME CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY | 84 | 1.38e-01 | 9.36e-02 | 0.977000 |
| REACTOME TRNA PROCESSING IN THE NUCLEUS | 58 | 1.39e-01 | 1.12e-01 | 0.977000 |
| REACTOME TRANSCRIPTION OF THE HIV GENOME | 66 | 1.40e-01 | 1.05e-01 | 0.977000 |
| REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY | 5 | 1.42e-01 | -3.79e-01 | 0.977000 |
| REACTOME PLASMA LIPOPROTEIN ASSEMBLY | 19 | 1.42e-01 | 1.94e-01 | 0.977000 |
| REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS | 188 | 1.43e-01 | -6.19e-02 | 0.977000 |
| REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION | 84 | 1.44e-01 | 9.23e-02 | 0.977000 |
| REACTOME DEFECTIVE B4GALT1 CAUSES B4GALT1 CDG CDG 2D | 8 | 1.45e-01 | 2.98e-01 | 0.977000 |
| REACTOME ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS | 41 | 1.45e-01 | -1.32e-01 | 0.977000 |
| REACTOME STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES | 16 | 1.45e-01 | -2.10e-01 | 0.977000 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING | 5 | 1.45e-01 | -3.76e-01 | 0.977000 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST | 18 | 1.46e-01 | -1.98e-01 | 0.977000 |
| REACTOME ENDOSOMAL VACUOLAR PATHWAY | 11 | 1.46e-01 | -2.53e-01 | 0.977000 |
| REACTOME SYNTHESIS OF PIPS AT THE ER MEMBRANE | 5 | 1.46e-01 | 3.75e-01 | 0.977000 |
| REACTOME ARACHIDONIC ACID METABOLISM | 57 | 1.47e-01 | -1.11e-01 | 0.977000 |
| REACTOME SYNTHESIS OF GDP MANNOSE | 5 | 1.48e-01 | 3.73e-01 | 0.977000 |
| REACTOME MHC CLASS II ANTIGEN PRESENTATION | 121 | 1.49e-01 | -7.60e-02 | 0.977000 |
| REACTOME PECAM1 INTERACTIONS | 12 | 1.50e-01 | 2.40e-01 | 0.977000 |
| REACTOME INTERFERON ALPHA BETA SIGNALING | 70 | 1.51e-01 | 9.94e-02 | 0.977000 |
| REACTOME TRAIL SIGNALING | 8 | 1.51e-01 | -2.93e-01 | 0.977000 |
| REACTOME METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS | 122 | 1.52e-01 | -7.51e-02 | 0.977000 |
| REACTOME BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA | 6 | 1.52e-01 | -3.38e-01 | 0.977000 |
| REACTOME HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS | 9 | 1.53e-01 | 2.75e-01 | 0.977000 |
| REACTOME CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN | 45 | 1.54e-01 | -1.23e-01 | 0.977000 |
| REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ | 6 | 1.54e-01 | 3.36e-01 | 0.977000 |
| REACTOME HDR THROUGH SINGLE STRAND ANNEALING SSA | 37 | 1.54e-01 | -1.35e-01 | 0.977000 |
| REACTOME ASSEMBLY OF THE HIV VIRION | 16 | 1.55e-01 | -2.05e-01 | 0.977000 |
| REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES | 78 | 1.55e-01 | -9.31e-02 | 0.977000 |
| REACTOME FC EPSILON RECEPTOR FCERI SIGNALING | 127 | 1.56e-01 | 7.29e-02 | 0.977000 |
| REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX | 21 | 1.57e-01 | -1.79e-01 | 0.977000 |
| REACTOME REGULATION OF NPAS4 GENE EXPRESSION | 13 | 1.57e-01 | 2.27e-01 | 0.977000 |
| REACTOME RESPONSE TO METAL IONS | 14 | 1.57e-01 | -2.18e-01 | 0.977000 |
| REACTOME COLLAGEN FORMATION | 88 | 1.58e-01 | 8.71e-02 | 0.977000 |
| REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | 24 | 1.58e-01 | 1.66e-01 | 0.977000 |
| REACTOME SIGNALING BY FGFR2 | 72 | 1.58e-01 | 9.62e-02 | 0.977000 |
| REACTOME PROSTANOID LIGAND RECEPTORS | 9 | 1.59e-01 | -2.71e-01 | 0.977000 |
| REACTOME REGULATION OF SIGNALING BY CBL | 22 | 1.59e-01 | 1.74e-01 | 0.977000 |
| REACTOME VESICLE MEDIATED TRANSPORT | 642 | 1.59e-01 | -3.26e-02 | 0.977000 |
| REACTOME TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX | 10 | 1.59e-01 | -2.57e-01 | 0.977000 |
| REACTOME INITIAL TRIGGERING OF COMPLEMENT | 21 | 1.59e-01 | 1.77e-01 | 0.977000 |
| REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION | 35 | 1.60e-01 | -1.37e-01 | 0.977000 |
| REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R | 52 | 1.61e-01 | 1.12e-01 | 0.977000 |
| REACTOME TRANS GOLGI NETWORK VESICLE BUDDING | 67 | 1.63e-01 | -9.86e-02 | 0.977000 |
| REACTOME MEIOSIS | 110 | 1.63e-01 | 7.69e-02 | 0.977000 |
| REACTOME ELASTIC FIBRE FORMATION | 44 | 1.64e-01 | -1.21e-01 | 0.977000 |
| REACTOME BUDDING AND MATURATION OF HIV VIRION | 28 | 1.64e-01 | -1.52e-01 | 0.977000 |
| REACTOME CIPROFLOXACIN ADME | 5 | 1.65e-01 | 3.59e-01 | 0.977000 |
| REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS | 34 | 1.66e-01 | 1.37e-01 | 0.977000 |
| REACTOME DOPAMINE RECEPTORS | 5 | 1.67e-01 | -3.57e-01 | 0.977000 |
| REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB | 5 | 1.67e-01 | -3.57e-01 | 0.977000 |
| REACTOME DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS | 15 | 1.68e-01 | 2.06e-01 | 0.977000 |
| REACTOME MRNA CAPPING | 28 | 1.69e-01 | 1.50e-01 | 0.977000 |
| REACTOME STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS | 10 | 1.69e-01 | -2.51e-01 | 0.977000 |
| REACTOME FGFR2 ALTERNATIVE SPLICING | 27 | 1.71e-01 | 1.52e-01 | 0.977000 |
| REACTOME REGULATION OF NPAS4 GENE TRANSCRIPTION | 5 | 1.72e-01 | 3.53e-01 | 0.977000 |
| REACTOME HYALURONAN UPTAKE AND DEGRADATION | 12 | 1.72e-01 | -2.28e-01 | 0.977000 |
| REACTOME LYSINE CATABOLISM | 12 | 1.73e-01 | -2.27e-01 | 0.977000 |
| REACTOME CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS | 100 | 1.73e-01 | -7.89e-02 | 0.977000 |
| REACTOME ACYL CHAIN REMODELING OF DAG AND TAG | 5 | 1.73e-01 | -3.52e-01 | 0.977000 |
| REACTOME SIGNAL ATTENUATION | 10 | 1.74e-01 | 2.48e-01 | 0.977000 |
| REACTOME BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS | 10 | 1.75e-01 | 2.48e-01 | 0.977000 |
| REACTOME EPHB MEDIATED FORWARD SIGNALING | 41 | 1.76e-01 | 1.22e-01 | 0.977000 |
| REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY DVL INTERACTING PROTEINS | 5 | 1.76e-01 | 3.49e-01 | 0.977000 |
| REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX | 57 | 1.76e-01 | 1.04e-01 | 0.977000 |
| REACTOME TRANSCRIPTIONAL REGULATION BY TP53 | 351 | 1.77e-01 | -4.20e-02 | 0.977000 |
| REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | 93 | 1.77e-01 | 8.09e-02 | 0.977000 |
| REACTOME FERTILIZATION | 26 | 1.78e-01 | 1.53e-01 | 0.977000 |
| REACTOME RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK | 47 | 1.79e-01 | -1.13e-01 | 0.977000 |
| REACTOME RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION | 6 | 1.79e-01 | 3.17e-01 | 0.977000 |
| REACTOME LYSOSPHINGOLIPID AND LPA RECEPTORS | 14 | 1.79e-01 | -2.07e-01 | 0.977000 |
| REACTOME ORGANIC CATION TRANSPORT | 10 | 1.80e-01 | -2.45e-01 | 0.977000 |
| REACTOME NEF AND SIGNAL TRANSDUCTION | 8 | 1.80e-01 | 2.74e-01 | 0.977000 |
| REACTOME COMPLEMENT CASCADE | 54 | 1.81e-01 | 1.05e-01 | 0.977000 |
| REACTOME AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS | 9 | 1.84e-01 | 2.56e-01 | 0.977000 |
| REACTOME SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX | 15 | 1.85e-01 | -1.97e-01 | 0.977000 |
| REACTOME OVARIAN TUMOR DOMAIN PROTEASES | 36 | 1.87e-01 | -1.27e-01 | 0.977000 |
| REACTOME RNA POLYMERASE II PRE TRANSCRIPTION EVENTS | 77 | 1.87e-01 | 8.70e-02 | 0.977000 |
| REACTOME S PHASE | 159 | 1.88e-01 | 6.05e-02 | 0.977000 |
| REACTOME ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS | 27 | 1.88e-01 | 1.46e-01 | 0.977000 |
| REACTOME UPTAKE OF DIETARY COBALAMINS INTO ENTEROCYTES | 9 | 1.88e-01 | 2.53e-01 | 0.977000 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES | 12 | 1.89e-01 | -2.19e-01 | 0.977000 |
| REACTOME GPVI MEDIATED ACTIVATION CASCADE | 35 | 1.90e-01 | 1.28e-01 | 0.977000 |
| REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM | 50 | 1.90e-01 | -1.07e-01 | 0.977000 |
| REACTOME RHO GTPASES ACTIVATE PKNS | 86 | 1.91e-01 | 8.15e-02 | 0.977000 |
| REACTOME RUNX3 REGULATES WNT SIGNALING | 8 | 1.95e-01 | 2.65e-01 | 0.977000 |
| REACTOME FASL CD95L SIGNALING | 5 | 1.95e-01 | 3.35e-01 | 0.977000 |
| REACTOME SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL | 25 | 1.95e-01 | 1.50e-01 | 0.977000 |
| REACTOME PROLONGED ERK ACTIVATION EVENTS | 14 | 1.96e-01 | 2.00e-01 | 0.977000 |
| REACTOME ANCHORING FIBRIL FORMATION | 13 | 1.98e-01 | 2.06e-01 | 0.977000 |
| REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION | 100 | 1.98e-01 | 7.45e-02 | 0.977000 |
| REACTOME ALK MUTANTS BIND TKIS | 12 | 1.98e-01 | -2.15e-01 | 0.977000 |
| REACTOME RECYCLING PATHWAY OF L1 | 43 | 2.00e-01 | -1.13e-01 | 0.977000 |
| REACTOME SCAVENGING BY CLASS A RECEPTORS | 19 | 2.00e-01 | 1.70e-01 | 0.977000 |
| REACTOME AURKA ACTIVATION BY TPX2 | 69 | 2.01e-01 | -8.89e-02 | 0.977000 |
| REACTOME E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS | 58 | 2.01e-01 | -9.70e-02 | 0.977000 |
| REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | 55 | 2.02e-01 | 9.94e-02 | 0.977000 |
| REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING | 6 | 2.02e-01 | 3.01e-01 | 0.977000 |
| REACTOME ESTABLISHMENT OF SISTER CHROMATID COHESION | 9 | 2.03e-01 | 2.45e-01 | 0.977000 |
| REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | 22 | 2.03e-01 | -1.57e-01 | 0.977000 |
| REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT | 222 | 2.04e-01 | 4.95e-02 | 0.977000 |
| REACTOME REGULATION OF RAS BY GAPS | 66 | 2.05e-01 | 9.02e-02 | 0.977000 |
| REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX | 15 | 2.05e-01 | -1.89e-01 | 0.977000 |
| REACTOME O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS | 38 | 2.06e-01 | -1.19e-01 | 0.977000 |
| REACTOME REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION | 84 | 2.06e-01 | -7.98e-02 | 0.977000 |
| REACTOME MTORC1 MEDIATED SIGNALLING | 23 | 2.06e-01 | -1.52e-01 | 0.977000 |
| REACTOME INTERLEUKIN 37 SIGNALING | 20 | 2.06e-01 | -1.63e-01 | 0.977000 |
| REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION | 32 | 2.07e-01 | 1.29e-01 | 0.977000 |
| REACTOME SIGNALING BY FLT3 FUSION PROTEINS | 19 | 2.09e-01 | -1.66e-01 | 0.977000 |
| REACTOME INTERLEUKIN 12 FAMILY SIGNALING | 53 | 2.09e-01 | -9.97e-02 | 0.977000 |
| REACTOME DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE | 17 | 2.09e-01 | 1.76e-01 | 0.977000 |
| REACTOME THE PHOTOTRANSDUCTION CASCADE | 32 | 2.10e-01 | 1.28e-01 | 0.977000 |
| REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION | 9 | 2.11e-01 | -2.41e-01 | 0.977000 |
| REACTOME MAPK1 ERK2 ACTIVATION | 9 | 2.11e-01 | 2.41e-01 | 0.977000 |
| REACTOME DIGESTION OF DIETARY CARBOHYDRATE | 6 | 2.12e-01 | 2.94e-01 | 0.977000 |
| REACTOME MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS | 7 | 2.13e-01 | 2.72e-01 | 0.977000 |
| REACTOME REGULATION OF IFNA IFNB SIGNALING | 23 | 2.14e-01 | 1.50e-01 | 0.977000 |
| REACTOME MEIOTIC SYNAPSIS | 73 | 2.14e-01 | 8.41e-02 | 0.977000 |
| REACTOME MITOCHONDRIAL BIOGENESIS | 87 | 2.14e-01 | -7.71e-02 | 0.977000 |
| REACTOME SUMO IS CONJUGATED TO E1 UBA2 SAE1 | 5 | 2.14e-01 | 3.21e-01 | 0.977000 |
| REACTOME TERMINAL PATHWAY OF COMPLEMENT | 8 | 2.14e-01 | 2.54e-01 | 0.977000 |
| REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER | 81 | 2.15e-01 | -7.97e-02 | 0.977000 |
| REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING | 30 | 2.15e-01 | 1.31e-01 | 0.977000 |
| REACTOME METABOLISM OF AMINE DERIVED HORMONES | 17 | 2.15e-01 | 1.74e-01 | 0.977000 |
| REACTOME FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS | 8 | 2.15e-01 | -2.53e-01 | 0.977000 |
| REACTOME DEFECTS IN VITAMIN AND COFACTOR METABOLISM | 21 | 2.16e-01 | -1.56e-01 | 0.977000 |
| REACTOME CD28 DEPENDENT PI3K AKT SIGNALING | 22 | 2.16e-01 | 1.52e-01 | 0.977000 |
| REACTOME PROCESSING AND ACTIVATION OF SUMO | 10 | 2.16e-01 | 2.26e-01 | 0.977000 |
| REACTOME HIV TRANSCRIPTION INITIATION | 43 | 2.17e-01 | 1.09e-01 | 0.977000 |
| REACTOME EUKARYOTIC TRANSLATION INITIATION | 110 | 2.17e-01 | 6.81e-02 | 0.977000 |
| REACTOME IRE1ALPHA ACTIVATES CHAPERONES | 48 | 2.18e-01 | -1.03e-01 | 0.977000 |
| REACTOME CHYLOMICRON REMODELING | 10 | 2.18e-01 | 2.25e-01 | 0.977000 |
| REACTOME KSRP KHSRP BINDS AND DESTABILIZES MRNA | 17 | 2.18e-01 | 1.72e-01 | 0.977000 |
| REACTOME ACTIVATION OF PPARGC1A PGC 1ALPHA BY PHOSPHORYLATION | 10 | 2.19e-01 | -2.24e-01 | 0.977000 |
| REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | 9 | 2.19e-01 | 2.36e-01 | 0.977000 |
| REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | 13 | 2.20e-01 | 1.97e-01 | 0.977000 |
| REACTOME INTRA GOLGI TRAFFIC | 43 | 2.21e-01 | -1.08e-01 | 0.977000 |
| REACTOME OXIDATIVE STRESS INDUCED SENESCENCE | 118 | 2.22e-01 | 6.51e-02 | 0.977000 |
| REACTOME DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15 | 8 | 2.23e-01 | 2.49e-01 | 0.977000 |
| REACTOME FOXO MEDIATED TRANSCRIPTION | 65 | 2.23e-01 | 8.74e-02 | 0.977000 |
| REACTOME RHOBTB GTPASE CYCLE | 34 | 2.23e-01 | -1.21e-01 | 0.977000 |
| REACTOME SIGNALING BY ERBB4 | 57 | 2.24e-01 | -9.32e-02 | 0.977000 |
| REACTOME RESOLUTION OF D LOOP STRUCTURES | 33 | 2.24e-01 | -1.22e-01 | 0.977000 |
| REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | 99 | 2.24e-01 | 7.08e-02 | 0.977000 |
| REACTOME DNA METHYLATION | 58 | 2.25e-01 | 9.20e-02 | 0.977000 |
| REACTOME BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA | 5 | 2.27e-01 | -3.12e-01 | 0.977000 |
| REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF | 53 | 2.27e-01 | -9.59e-02 | 0.977000 |
| REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS | 113 | 2.28e-01 | 6.57e-02 | 0.977000 |
| REACTOME METABOLISM OF POLYAMINES | 56 | 2.28e-01 | 9.32e-02 | 0.977000 |
| REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | 105 | 2.29e-01 | 6.80e-02 | 0.977000 |
| REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION | 8 | 2.29e-01 | 2.45e-01 | 0.977000 |
| REACTOME CONJUGATION OF BENZOATE WITH GLYCINE | 6 | 2.30e-01 | 2.83e-01 | 0.977000 |
| REACTOME SIGNALING BY BMP | 27 | 2.30e-01 | -1.34e-01 | 0.977000 |
| REACTOME DISEASES OF IMMUNE SYSTEM | 29 | 2.31e-01 | 1.29e-01 | 0.977000 |
| REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION | 138 | 2.32e-01 | 5.89e-02 | 0.977000 |
| REACTOME UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN | 6 | 2.32e-01 | 2.82e-01 | 0.977000 |
| REACTOME REGULATION OF RUNX3 EXPRESSION AND ACTIVITY | 54 | 2.33e-01 | 9.38e-02 | 0.977000 |
| REACTOME HSF1 DEPENDENT TRANSACTIVATION | 37 | 2.35e-01 | -1.13e-01 | 0.977000 |
| REACTOME DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM | 38 | 2.35e-01 | 1.11e-01 | 0.977000 |
| REACTOME TRNA PROCESSING | 105 | 2.36e-01 | 6.69e-02 | 0.977000 |
| REACTOME SPERM MOTILITY AND TAXES | 9 | 2.36e-01 | 2.28e-01 | 0.977000 |
| REACTOME DEFECTIVE CHST3 CAUSES SEDCJD | 7 | 2.36e-01 | 2.59e-01 | 0.977000 |
| REACTOME STRIATED MUSCLE CONTRACTION | 35 | 2.39e-01 | 1.15e-01 | 0.977000 |
| REACTOME SHC1 EVENTS IN ERBB2 SIGNALING | 22 | 2.41e-01 | -1.45e-01 | 0.977000 |
| REACTOME REGULATED NECROSIS | 57 | 2.41e-01 | -8.98e-02 | 0.977000 |
| REACTOME GERM LAYER FORMATION AT GASTRULATION | 17 | 2.41e-01 | -1.64e-01 | 0.977000 |
| REACTOME INITIATION OF NUCLEAR ENVELOPE NE REFORMATION | 18 | 2.41e-01 | -1.59e-01 | 0.977000 |
| REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET | 8 | 2.42e-01 | -2.39e-01 | 0.977000 |
| REACTOME SIGNALING BY FGFR4 IN DISEASE | 11 | 2.42e-01 | 2.04e-01 | 0.977000 |
| REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC | 198 | 2.43e-01 | -4.82e-02 | 0.977000 |
| REACTOME PREGNENOLONE BIOSYNTHESIS | 12 | 2.43e-01 | -1.95e-01 | 0.977000 |
| REACTOME NFE2L2 REGULATING ANTI OXIDANT DETOXIFICATION ENZYMES | 17 | 2.44e-01 | -1.63e-01 | 0.977000 |
| REACTOME ER TO GOLGI ANTEROGRADE TRANSPORT | 152 | 2.44e-01 | -5.47e-02 | 0.977000 |
| REACTOME PTK6 REGULATES CELL CYCLE | 6 | 2.45e-01 | 2.74e-01 | 0.977000 |
| REACTOME PROTEIN UBIQUITINATION | 76 | 2.46e-01 | -7.69e-02 | 0.977000 |
| REACTOME DEGRADATION OF DVL | 56 | 2.46e-01 | 8.95e-02 | 0.977000 |
| REACTOME TELOMERE MAINTENANCE | 106 | 2.47e-01 | 6.51e-02 | 0.977000 |
| REACTOME CELL CELL JUNCTION ORGANIZATION | 64 | 2.50e-01 | -8.32e-02 | 0.977000 |
| REACTOME REGULATION OF IFNG SIGNALING | 14 | 2.51e-01 | 1.77e-01 | 0.977000 |
| REACTOME HDMS DEMETHYLATE HISTONES | 40 | 2.51e-01 | 1.05e-01 | 0.977000 |
| REACTOME HSF1 ACTIVATION | 29 | 2.52e-01 | -1.23e-01 | 0.977000 |
| REACTOME VXPX CARGO TARGETING TO CILIUM | 20 | 2.52e-01 | -1.48e-01 | 0.977000 |
| REACTOME SIGNALING BY KIT IN DISEASE | 20 | 2.52e-01 | 1.48e-01 | 0.977000 |
| REACTOME SIGNALING BY MET | 78 | 2.53e-01 | 7.48e-02 | 0.977000 |
| REACTOME HDL ASSEMBLY | 8 | 2.54e-01 | 2.33e-01 | 0.977000 |
| REACTOME AZATHIOPRINE ADME | 22 | 2.55e-01 | -1.40e-01 | 0.977000 |
| REACTOME RHOJ GTPASE CYCLE | 51 | 2.55e-01 | -9.22e-02 | 0.977000 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE | 5 | 2.56e-01 | -2.93e-01 | 0.977000 |
| REACTOME SYNTHESIS OF 15 EICOSATETRAENOIC ACID DERIVATIVES | 6 | 2.57e-01 | -2.67e-01 | 0.977000 |
| REACTOME KERATAN SULFATE DEGRADATION | 13 | 2.57e-01 | 1.82e-01 | 0.977000 |
| REACTOME ION CHANNEL TRANSPORT | 172 | 2.57e-01 | 5.01e-02 | 0.977000 |
| REACTOME PEPTIDE LIGAND BINDING RECEPTORS | 188 | 2.59e-01 | -4.78e-02 | 0.977000 |
| REACTOME TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE | 20 | 2.60e-01 | -1.46e-01 | 0.977000 |
| REACTOME HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE | 43 | 2.60e-01 | -9.93e-02 | 0.977000 |
| REACTOME RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES TREGS | 9 | 2.60e-01 | -2.17e-01 | 0.977000 |
| REACTOME DNA REPLICATION PRE INITIATION | 150 | 2.60e-01 | 5.33e-02 | 0.977000 |
| REACTOME SIGNALING BY MAPK MUTANTS | 6 | 2.60e-01 | 2.65e-01 | 0.977000 |
| REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES | 16 | 2.61e-01 | 1.62e-01 | 0.977000 |
| REACTOME PHASE 1 INACTIVATION OF FAST NA CHANNELS | 6 | 2.62e-01 | 2.65e-01 | 0.977000 |
| REACTOME DEADENYLATION DEPENDENT MRNA DECAY | 56 | 2.64e-01 | 8.62e-02 | 0.977000 |
| REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | 111 | 2.65e-01 | 6.13e-02 | 0.977000 |
| REACTOME RNA POLYMERASE II TRANSCRIBES SNRNA GENES | 77 | 2.65e-01 | 7.35e-02 | 0.977000 |
| REACTOME ACTIVATION OF NIMA KINASES NEK9 NEK6 NEK7 | 7 | 2.65e-01 | -2.43e-01 | 0.977000 |
| REACTOME ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS | 17 | 2.65e-01 | -1.56e-01 | 0.977000 |
| REACTOME INSULIN RECEPTOR RECYCLING | 29 | 2.66e-01 | 1.19e-01 | 0.977000 |
| REACTOME DISEASES OF GLYCOSYLATION | 137 | 2.66e-01 | 5.50e-02 | 0.977000 |
| REACTOME OAS ANTIVIRAL RESPONSE | 8 | 2.66e-01 | 2.27e-01 | 0.977000 |
| REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN | 37 | 2.67e-01 | -1.05e-01 | 0.977000 |
| REACTOME PCP CE PATHWAY | 91 | 2.67e-01 | 6.73e-02 | 0.977000 |
| REACTOME TRNA AMINOACYLATION | 40 | 2.68e-01 | -1.01e-01 | 0.977000 |
| REACTOME BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA | 17 | 2.69e-01 | 1.55e-01 | 0.977000 |
| REACTOME PARACETAMOL ADME | 26 | 2.69e-01 | -1.25e-01 | 0.977000 |
| REACTOME GLUCONEOGENESIS | 33 | 2.70e-01 | -1.11e-01 | 0.977000 |
| REACTOME ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE | 9 | 2.70e-01 | 2.12e-01 | 0.977000 |
| REACTOME RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY | 14 | 2.71e-01 | 1.70e-01 | 0.977000 |
| REACTOME AGGREPHAGY | 42 | 2.72e-01 | -9.80e-02 | 0.977000 |
| REACTOME NEURONAL SYSTEM | 388 | 2.72e-01 | -3.25e-02 | 0.977000 |
| REACTOME GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER | 25 | 2.72e-01 | -1.27e-01 | 0.977000 |
| REACTOME INSULIN PROCESSING | 24 | 2.73e-01 | -1.29e-01 | 0.977000 |
| REACTOME SYNTHESIS OF DOLICHYL PHOSPHATE | 6 | 2.73e-01 | 2.58e-01 | 0.977000 |
| REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES | 7 | 2.73e-01 | -2.39e-01 | 0.977000 |
| REACTOME VLDLR INTERNALISATION AND DEGRADATION | 16 | 2.74e-01 | -1.58e-01 | 0.977000 |
| REACTOME CILIUM ASSEMBLY | 190 | 2.74e-01 | -4.60e-02 | 0.977000 |
| REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM | 23 | 2.75e-01 | 1.32e-01 | 0.977000 |
| REACTOME POTENTIAL THERAPEUTICS FOR SARS | 92 | 2.75e-01 | 6.58e-02 | 0.977000 |
| REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE | 37 | 2.76e-01 | -1.03e-01 | 0.977000 |
| REACTOME PYROPTOSIS | 27 | 2.77e-01 | -1.21e-01 | 0.977000 |
| REACTOME NEUROFASCIN INTERACTIONS | 6 | 2.77e-01 | 2.56e-01 | 0.977000 |
| REACTOME TRANSCRIPTIONAL REGULATION BY RUNX3 | 94 | 2.78e-01 | 6.47e-02 | 0.977000 |
| REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION | 59 | 2.79e-01 | -8.16e-02 | 0.977000 |
| REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP | 104 | 2.80e-01 | 6.14e-02 | 0.977000 |
| REACTOME TRANSPORT OF SMALL MOLECULES | 697 | 2.80e-01 | 2.40e-02 | 0.977000 |
| REACTOME CITRIC ACID CYCLE TCA CYCLE | 21 | 2.81e-01 | -1.36e-01 | 0.977000 |
| REACTOME BH3 ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI APOPTOTIC BCL 2 MEMBERS | 9 | 2.81e-01 | 2.07e-01 | 0.977000 |
| REACTOME ABACAVIR TRANSMEMBRANE TRANSPORT | 5 | 2.82e-01 | -2.78e-01 | 0.977000 |
| REACTOME SEROTONIN NEUROTRANSMITTER RELEASE CYCLE | 17 | 2.83e-01 | -1.50e-01 | 0.977000 |
| REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | 28 | 2.84e-01 | -1.17e-01 | 0.977000 |
| REACTOME REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA | 15 | 2.84e-01 | -1.60e-01 | 0.977000 |
| REACTOME PI3K EVENTS IN ERBB2 SIGNALING | 16 | 2.84e-01 | -1.55e-01 | 0.977000 |
| REACTOME TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY | 30 | 2.84e-01 | -1.13e-01 | 0.977000 |
| REACTOME SIGNALING BY PDGF | 57 | 2.84e-01 | 8.20e-02 | 0.977000 |
| REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING | 33 | 2.84e-01 | 1.08e-01 | 0.977000 |
| REACTOME NEUROTOXICITY OF CLOSTRIDIUM TOXINS | 10 | 2.85e-01 | -1.95e-01 | 0.977000 |
| REACTOME NONSENSE MEDIATED DECAY NMD | 107 | 2.85e-01 | 5.98e-02 | 0.977000 |
| REACTOME METABOLISM OF CARBOHYDRATES | 279 | 2.85e-01 | -3.72e-02 | 0.977000 |
| REACTOME LAMININ INTERACTIONS | 28 | 2.85e-01 | 1.17e-01 | 0.977000 |
| REACTOME MITOTIC PROMETAPHASE | 194 | 2.85e-01 | -4.45e-02 | 0.977000 |
| REACTOME INTERLEUKIN 12 SIGNALING | 43 | 2.85e-01 | -9.42e-02 | 0.977000 |
| REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING | 34 | 2.86e-01 | -1.06e-01 | 0.977000 |
| REACTOME ONCOGENIC MAPK SIGNALING | 79 | 2.86e-01 | 6.94e-02 | 0.977000 |
| REACTOME ANTIMICROBIAL PEPTIDES | 76 | 2.86e-01 | -7.08e-02 | 0.977000 |
| REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | 20 | 2.86e-01 | -1.38e-01 | 0.977000 |
| REACTOME IRS ACTIVATION | 5 | 2.86e-01 | 2.75e-01 | 0.977000 |
| REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES | 12 | 2.88e-01 | 1.77e-01 | 0.977000 |
| REACTOME INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING | 103 | 2.88e-01 | -6.05e-02 | 0.977000 |
| REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | 81 | 2.89e-01 | -6.81e-02 | 0.977000 |
| REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE GIP | 12 | 2.92e-01 | 1.76e-01 | 0.977000 |
| REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS | 55 | 2.92e-01 | 8.21e-02 | 0.977000 |
| REACTOME TELOMERE C STRAND SYNTHESIS INITIATION | 12 | 2.93e-01 | 1.75e-01 | 0.977000 |
| REACTOME RESOLUTION OF ABASIC SITES AP SITES | 38 | 2.94e-01 | -9.84e-02 | 0.977000 |
| REACTOME SIGNALING BY WNT | 318 | 2.94e-01 | 3.42e-02 | 0.977000 |
| REACTOME ATTENUATION PHASE | 27 | 2.95e-01 | -1.17e-01 | 0.977000 |
| REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION | 31 | 2.95e-01 | -1.09e-01 | 0.977000 |
| REACTOME MASTL FACILITATES MITOTIC PROGRESSION | 10 | 2.95e-01 | -1.91e-01 | 0.977000 |
| REACTOME TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA | 17 | 2.96e-01 | 1.46e-01 | 0.977000 |
| REACTOME ERYTHROPOIETIN ACTIVATES RAS | 14 | 2.96e-01 | 1.61e-01 | 0.977000 |
| REACTOME METABOLISM OF FOLATE AND PTERINES | 17 | 2.97e-01 | -1.46e-01 | 0.977000 |
| REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS | 63 | 2.98e-01 | 7.59e-02 | 0.977000 |
| REACTOME BINDING OF TCF LEF CTNNB1 TO TARGET GENE PROMOTERS | 8 | 2.99e-01 | 2.12e-01 | 0.977000 |
| REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III | 31 | 2.99e-01 | -1.08e-01 | 0.977000 |
| REACTOME SARS COV 2 TARGETS PDZ PROTEINS IN CELL CELL JUNCTION | 5 | 3.00e-01 | -2.68e-01 | 0.977000 |
| REACTOME ASPIRIN ADME | 42 | 3.00e-01 | 9.24e-02 | 0.977000 |
| REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | 51 | 3.02e-01 | -8.36e-02 | 0.977000 |
| REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | 16 | 3.02e-01 | 1.49e-01 | 0.977000 |
| REACTOME REGULATION OF NPAS4 MRNA TRANSLATION | 9 | 3.03e-01 | 1.98e-01 | 0.977000 |
| REACTOME PIWI INTERACTING RNA PIRNA BIOGENESIS | 29 | 3.03e-01 | 1.11e-01 | 0.977000 |
| REACTOME RNA POLYMERASE I TRANSCRIPTION TERMINATION | 30 | 3.03e-01 | 1.09e-01 | 0.977000 |
| REACTOME MATURATION OF PROTEIN 3A | 9 | 3.06e-01 | -1.97e-01 | 0.977000 |
| REACTOME PURINE SALVAGE | 12 | 3.06e-01 | 1.71e-01 | 0.977000 |
| REACTOME SCAVENGING BY CLASS F RECEPTORS | 6 | 3.08e-01 | -2.40e-01 | 0.977000 |
| REACTOME SYNAPTIC ADHESION LIKE MOLECULES | 19 | 3.09e-01 | -1.35e-01 | 0.977000 |
| REACTOME ACYL CHAIN REMODELLING OF PC | 27 | 3.09e-01 | 1.13e-01 | 0.977000 |
| REACTOME VITAMIN B2 RIBOFLAVIN METABOLISM | 7 | 3.09e-01 | -2.22e-01 | 0.977000 |
| REACTOME STIMULI SENSING CHANNELS | 100 | 3.09e-01 | 5.88e-02 | 0.977000 |
| REACTOME NGF STIMULATED TRANSCRIPTION | 38 | 3.10e-01 | -9.53e-02 | 0.977000 |
| REACTOME DISEASES OF DNA REPAIR | 51 | 3.10e-01 | -8.22e-02 | 0.977000 |
| REACTOME COENZYME A BIOSYNTHESIS | 8 | 3.10e-01 | 2.07e-01 | 0.977000 |
| REACTOME RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX | 29 | 3.11e-01 | -1.09e-01 | 0.977000 |
| REACTOME RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION | 6 | 3.11e-01 | -2.39e-01 | 0.977000 |
| REACTOME FORMATION OF TC NER PRE INCISION COMPLEX | 51 | 3.11e-01 | 8.20e-02 | 0.977000 |
| REACTOME SIGNALING BY FGFR1 | 49 | 3.11e-01 | 8.36e-02 | 0.977000 |
| REACTOME CHYLOMICRON ASSEMBLY | 10 | 3.11e-01 | 1.85e-01 | 0.977000 |
| REACTOME INTERLEUKIN 35 SIGNALLING | 12 | 3.11e-01 | 1.69e-01 | 0.977000 |
| REACTOME ERBB2 ACTIVATES PTK6 SIGNALING | 13 | 3.11e-01 | -1.62e-01 | 0.977000 |
| REACTOME FRS MEDIATED FGFR4 SIGNALING | 21 | 3.12e-01 | 1.27e-01 | 0.977000 |
| REACTOME PASSIVE TRANSPORT BY AQUAPORINS | 13 | 3.12e-01 | -1.62e-01 | 0.977000 |
| REACTOME INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | 28 | 3.13e-01 | -1.10e-01 | 0.977000 |
| REACTOME ENDOGENOUS STEROLS | 26 | 3.13e-01 | 1.14e-01 | 0.977000 |
| REACTOME REPRESSION OF WNT TARGET GENES | 14 | 3.14e-01 | 1.55e-01 | 0.977000 |
| REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21 | 59 | 3.14e-01 | 7.57e-02 | 0.977000 |
| REACTOME HEMOSTASIS | 591 | 3.14e-01 | -2.42e-02 | 0.977000 |
| REACTOME LIPOPHAGY | 9 | 3.15e-01 | -1.93e-01 | 0.977000 |
| REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K | 12 | 3.16e-01 | 1.67e-01 | 0.977000 |
| REACTOME DEX H BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION | 7 | 3.17e-01 | 2.18e-01 | 0.977000 |
| REACTOME ZINC TRANSPORTERS | 15 | 3.17e-01 | 1.49e-01 | 0.977000 |
| REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA | 25 | 3.17e-01 | 1.16e-01 | 0.977000 |
| REACTOME ESTROGEN DEPENDENT GENE EXPRESSION | 140 | 3.17e-01 | 4.90e-02 | 0.977000 |
| REACTOME CARGO CONCENTRATION IN THE ER | 32 | 3.18e-01 | -1.02e-01 | 0.977000 |
| REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION | 361 | 3.18e-01 | -3.06e-02 | 0.977000 |
| REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS | 16 | 3.18e-01 | 1.44e-01 | 0.977000 |
| REACTOME RUNX3 REGULATES YAP1 MEDIATED TRANSCRIPTION | 8 | 3.18e-01 | 2.04e-01 | 0.977000 |
| REACTOME SIGNALLING TO ERKS | 34 | 3.20e-01 | 9.86e-02 | 0.977000 |
| REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING | 28 | 3.21e-01 | 1.08e-01 | 0.977000 |
| REACTOME MATURATION OF SARS COV 1 SPIKE PROTEIN | 5 | 3.21e-01 | -2.56e-01 | 0.977000 |
| REACTOME PRE NOTCH EXPRESSION AND PROCESSING | 112 | 3.21e-01 | 5.42e-02 | 0.977000 |
| REACTOME SUMOYLATION OF SUMOYLATION PROTEINS | 35 | 3.21e-01 | 9.69e-02 | 0.977000 |
| REACTOME G ALPHA S SIGNALLING EVENTS | 155 | 3.21e-01 | 4.62e-02 | 0.977000 |
| REACTOME PI3K AKT ACTIVATION | 9 | 3.22e-01 | 1.91e-01 | 0.977000 |
| REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | 16 | 3.22e-01 | 1.43e-01 | 0.977000 |
| REACTOME FATTY ACID METABOLISM | 170 | 3.24e-01 | -4.39e-02 | 0.977000 |
| REACTOME CATION COUPLED CHLORIDE COTRANSPORTERS | 7 | 3.24e-01 | -2.15e-01 | 0.977000 |
| REACTOME GABA RECEPTOR ACTIVATION | 57 | 3.25e-01 | -7.54e-02 | 0.977000 |
| REACTOME PI 3K CASCADE FGFR4 | 19 | 3.25e-01 | 1.30e-01 | 0.977000 |
| REACTOME VOLTAGE GATED POTASSIUM CHANNELS | 42 | 3.25e-01 | -8.77e-02 | 0.977000 |
| REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | 17 | 3.26e-01 | 1.38e-01 | 0.977000 |
| REACTOME MRNA SPLICING | 197 | 3.28e-01 | 4.04e-02 | 0.977000 |
| REACTOME INACTIVATION OF CSF3 G CSF SIGNALING | 25 | 3.28e-01 | 1.13e-01 | 0.977000 |
| REACTOME ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS | 87 | 3.28e-01 | -6.06e-02 | 0.977000 |
| REACTOME CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND | 16 | 3.29e-01 | -1.41e-01 | 0.977000 |
| REACTOME CALNEXIN CALRETICULIN CYCLE | 26 | 3.29e-01 | -1.11e-01 | 0.977000 |
| REACTOME ACYL CHAIN REMODELLING OF PI | 17 | 3.30e-01 | 1.37e-01 | 0.977000 |
| REACTOME INTERLEUKIN 2 SIGNALING | 11 | 3.31e-01 | -1.69e-01 | 0.977000 |
| REACTOME CD22 MEDIATED BCR REGULATION | 5 | 3.31e-01 | 2.51e-01 | 0.977000 |
| REACTOME SIGNALING BY TGFB FAMILY MEMBERS | 119 | 3.31e-01 | -5.16e-02 | 0.977000 |
| REACTOME SYNTHESIS OF 5 EICOSATETRAENOIC ACIDS | 9 | 3.31e-01 | -1.87e-01 | 0.977000 |
| REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | 353 | 3.32e-01 | -3.00e-02 | 0.977000 |
| REACTOME SIGNALING BY ALK IN CANCER | 53 | 3.34e-01 | -7.67e-02 | 0.977000 |
| REACTOME AUTOPHAGY | 144 | 3.34e-01 | -4.66e-02 | 0.977000 |
| REACTOME REACTIONS SPECIFIC TO THE COMPLEX N GLYCAN SYNTHESIS PATHWAY | 10 | 3.34e-01 | -1.76e-01 | 0.977000 |
| REACTOME FORMATION OF XYLULOSE 5 PHOSPHATE | 5 | 3.35e-01 | 2.49e-01 | 0.977000 |
| REACTOME COMMON PATHWAY OF FIBRIN CLOT FORMATION | 21 | 3.35e-01 | -1.21e-01 | 0.977000 |
| REACTOME ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING | 23 | 3.35e-01 | 1.16e-01 | 0.977000 |
| REACTOME SIGNALING BY FGFR4 | 40 | 3.36e-01 | 8.79e-02 | 0.977000 |
| REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | 46 | 3.36e-01 | 8.20e-02 | 0.977000 |
| REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS | 81 | 3.36e-01 | 6.18e-02 | 0.977000 |
| REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | 18 | 3.36e-01 | 1.31e-01 | 0.977000 |
| REACTOME MEIOTIC RECOMBINATION | 80 | 3.38e-01 | 6.20e-02 | 0.977000 |
| REACTOME SIGNALING BY ERYTHROPOIETIN | 25 | 3.38e-01 | 1.11e-01 | 0.977000 |
| REACTOME DNA DAMAGE REVERSAL | 8 | 3.38e-01 | -1.95e-01 | 0.977000 |
| REACTOME G ALPHA Q SIGNALLING EVENTS | 206 | 3.39e-01 | -3.87e-02 | 0.977000 |
| REACTOME C TYPE LECTIN RECEPTORS CLRS | 136 | 3.39e-01 | 4.74e-02 | 0.977000 |
| REACTOME INTRAFLAGELLAR TRANSPORT | 50 | 3.40e-01 | -7.81e-02 | 0.977000 |
| REACTOME MRNA EDITING | 10 | 3.40e-01 | 1.74e-01 | 0.977000 |
| REACTOME EPH EPHRIN SIGNALING | 90 | 3.40e-01 | 5.82e-02 | 0.977000 |
| REACTOME SYNTHESIS OF 12 EICOSATETRAENOIC ACID DERIVATIVES | 7 | 3.40e-01 | -2.08e-01 | 0.977000 |
| REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE | 52 | 3.41e-01 | -7.64e-02 | 0.977000 |
| REACTOME HYALURONAN METABOLISM | 17 | 3.41e-01 | -1.33e-01 | 0.977000 |
| REACTOME COHESIN LOADING ONTO CHROMATIN | 8 | 3.42e-01 | 1.94e-01 | 0.977000 |
| REACTOME G1 S SPECIFIC TRANSCRIPTION | 28 | 3.42e-01 | -1.04e-01 | 0.977000 |
| REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS | 28 | 3.42e-01 | 1.04e-01 | 0.977000 |
| REACTOME NEGATIVE REGULATION OF MAPK PATHWAY | 41 | 3.42e-01 | 8.58e-02 | 0.977000 |
| REACTOME COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING | 32 | 3.43e-01 | -9.69e-02 | 0.977000 |
| REACTOMEMATURATION OF SARS COV 1 NUCLEOPROTEIN | 11 | 3.43e-01 | 1.65e-01 | 0.977000 |
| REACTOME BETA CATENIN INDEPENDENT WNT SIGNALING | 145 | 3.43e-01 | 4.56e-02 | 0.977000 |
| REACTOME CYP2E1 REACTIONS | 10 | 3.44e-01 | -1.73e-01 | 0.977000 |
| REACTOME REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE | 81 | 3.47e-01 | 6.05e-02 | 0.978000 |
| REACTOME P75NTR SIGNALS VIA NF KB | 15 | 3.48e-01 | 1.40e-01 | 0.978000 |
| REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL | 12 | 3.48e-01 | 1.57e-01 | 0.978000 |
| REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV 1 INFECTION | 5 | 3.50e-01 | -2.41e-01 | 0.978000 |
| REACTOME TOXICITY OF BOTULINUM TOXIN TYPE D BOTD | 5 | 3.51e-01 | -2.41e-01 | 0.978000 |
| REACTOME RHOBTB3 ATPASE CYCLE | 8 | 3.51e-01 | -1.90e-01 | 0.978000 |
| REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | 21 | 3.51e-01 | -1.17e-01 | 0.978000 |
| REACTOME RND1 GTPASE CYCLE | 41 | 3.53e-01 | -8.39e-02 | 0.978000 |
| REACTOME NUCLEOTIDE BIOSYNTHESIS | 14 | 3.53e-01 | 1.43e-01 | 0.978000 |
| REACTOME RAS PROCESSING | 22 | 3.53e-01 | 1.14e-01 | 0.978000 |
| REACTOME VITAMINS | 6 | 3.54e-01 | -2.19e-01 | 0.978000 |
| REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2 | 13 | 3.54e-01 | -1.48e-01 | 0.978000 |
| REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION | 20 | 3.54e-01 | -1.20e-01 | 0.978000 |
| REACTOME ACYL CHAIN REMODELING OF CL | 5 | 3.55e-01 | -2.39e-01 | 0.978000 |
| REACTOME PREVENTION OF PHAGOSOMAL LYSOSOMAL FUSION | 9 | 3.55e-01 | 1.78e-01 | 0.978000 |
| REACTOME FGFR1B LIGAND BINDING AND ACTIVATION | 6 | 3.56e-01 | 2.18e-01 | 0.978000 |
| REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | 9 | 3.56e-01 | -1.78e-01 | 0.978000 |
| REACTOME ATORVASTATIN ADME | 9 | 3.56e-01 | 1.78e-01 | 0.978000 |
| REACTOME INTERLEUKIN 9 SIGNALING | 7 | 3.57e-01 | -2.01e-01 | 0.978000 |
| REACTOME COPI MEDIATED ANTEROGRADE TRANSPORT | 101 | 3.57e-01 | -5.31e-02 | 0.978000 |
| REACTOME METABOLISM OF FAT SOLUBLE VITAMINS | 46 | 3.57e-01 | 7.85e-02 | 0.978000 |
| REACTOME COPII MEDIATED VESICLE TRANSPORT | 66 | 3.57e-01 | -6.55e-02 | 0.978000 |
| REACTOME NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION | 20 | 3.59e-01 | -1.18e-01 | 0.980000 |
| REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | 45 | 3.61e-01 | 7.88e-02 | 0.980000 |
| REACTOME TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7 | 12 | 3.61e-01 | -1.52e-01 | 0.980000 |
| REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL | 15 | 3.61e-01 | 1.36e-01 | 0.980000 |
| REACTOME MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS | 17 | 3.61e-01 | -1.28e-01 | 0.980000 |
| REACTOME DIGESTION OF DIETARY LIPID | 7 | 3.62e-01 | -1.99e-01 | 0.980000 |
| REACTOME MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS | 13 | 3.65e-01 | -1.45e-01 | 0.982000 |
| REACTOME MET INTERACTS WITH TNS PROTEINS | 5 | 3.66e-01 | -2.34e-01 | 0.982000 |
| REACTOME O LINKED GLYCOSYLATION OF MUCINS | 61 | 3.66e-01 | 6.69e-02 | 0.982000 |
| REACTOME FORMATION OF PARAXIAL MESODERM | 22 | 3.66e-01 | -1.11e-01 | 0.982000 |
| REACTOME GROWTH HORMONE RECEPTOR SIGNALING | 24 | 3.67e-01 | 1.06e-01 | 0.982000 |
| REACTOME SUMOYLATION | 179 | 3.67e-01 | 3.91e-02 | 0.982000 |
| REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | 8 | 3.68e-01 | -1.84e-01 | 0.982000 |
| REACTOME SOS MEDIATED SIGNALLING | 7 | 3.68e-01 | 1.96e-01 | 0.982000 |
| REACTOME SARS COV 1 INFECTION | 136 | 3.69e-01 | -4.46e-02 | 0.982000 |
| REACTOME COBALAMIN CBL METABOLISM | 7 | 3.69e-01 | -1.96e-01 | 0.982000 |
| REACTOME MELANIN BIOSYNTHESIS | 5 | 3.70e-01 | -2.32e-01 | 0.982000 |
| REACTOME SIGNALING BY THE B CELL RECEPTOR BCR | 106 | 3.71e-01 | 5.03e-02 | 0.982000 |
| REACTOME FBXW7 MUTANTS AND NOTCH1 IN CANCER | 5 | 3.71e-01 | -2.31e-01 | 0.982000 |
| REACTOME SIGNALING BY FLT3 ITD AND TKD MUTANTS | 16 | 3.72e-01 | -1.29e-01 | 0.982000 |
| REACTOME NEGATIVE REGULATION OF NOTCH4 SIGNALING | 53 | 3.72e-01 | 7.09e-02 | 0.982000 |
| REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION | 12 | 3.72e-01 | -1.49e-01 | 0.982000 |
| REACTOME PYRIMIDINE CATABOLISM | 12 | 3.73e-01 | -1.48e-01 | 0.982000 |
| REACTOME REGULATION OF SIGNALING BY NODAL | 9 | 3.74e-01 | 1.71e-01 | 0.982000 |
| REACTOME TNFR1 INDUCED PROAPOPTOTIC SIGNALING | 23 | 3.75e-01 | -1.07e-01 | 0.982000 |
| REACTOME FREE FATTY ACID RECEPTORS | 5 | 3.75e-01 | -2.29e-01 | 0.982000 |
| REACTOME PEPTIDE HORMONE METABOLISM | 84 | 3.76e-01 | -5.59e-02 | 0.982000 |
| REACTOME FOLDING OF ACTIN BY CCT TRIC | 10 | 3.76e-01 | 1.62e-01 | 0.982000 |
| REACTOME ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY | 5 | 3.78e-01 | 2.28e-01 | 0.985000 |
| REACTOME ACYL CHAIN REMODELLING OF PS | 22 | 3.78e-01 | 1.08e-01 | 0.985000 |
| REACTOME RAS SIGNALING DOWNSTREAM OF NF1 LOSS OF FUNCTION VARIANTS | 7 | 3.79e-01 | 1.92e-01 | 0.985000 |
| REACTOME METABOLISM OF VITAMINS AND COFACTORS | 185 | 3.80e-01 | -3.75e-02 | 0.985000 |
| REACTOME MUSCARINIC ACETYLCHOLINE RECEPTORS | 5 | 3.80e-01 | 2.27e-01 | 0.985000 |
| REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP | 41 | 3.82e-01 | -7.88e-02 | 0.990000 |
| REACTOME INTERLEUKIN 6 SIGNALING | 11 | 3.83e-01 | 1.52e-01 | 0.990000 |
| REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD4 | 15 | 3.84e-01 | -1.30e-01 | 0.990000 |
| REACTOME RHOBTB1 GTPASE CYCLE | 22 | 3.84e-01 | -1.07e-01 | 0.990000 |
| REACTOME FLT3 SIGNALING | 38 | 3.85e-01 | 8.15e-02 | 0.990000 |
| REACTOME METABOLISM OF STEROIDS | 150 | 3.87e-01 | 4.09e-02 | 0.993000 |
| REACTOME EPITHELIAL MESENCHYMAL TRANSITION EMT DURING GASTRULATION | 7 | 3.88e-01 | -1.88e-01 | 0.993000 |
| REACTOME INTERLEUKIN 18 SIGNALING | 8 | 3.89e-01 | -1.76e-01 | 0.993000 |
| REACTOME METHYLATION | 14 | 3.91e-01 | -1.32e-01 | 0.993000 |
| REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS | 15 | 3.92e-01 | 1.28e-01 | 0.993000 |
| REACTOME DISEASES OF CARBOHYDRATE METABOLISM | 31 | 3.93e-01 | -8.87e-02 | 0.993000 |
| REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS | 12 | 3.93e-01 | -1.43e-01 | 0.993000 |
| REACTOME UNWINDING OF DNA | 12 | 3.93e-01 | 1.42e-01 | 0.993000 |
| REACTOME KETONE BODY METABOLISM | 9 | 3.94e-01 | -1.64e-01 | 0.993000 |
| REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION | 62 | 3.95e-01 | 6.25e-02 | 0.993000 |
| REACTOME G PROTEIN MEDIATED EVENTS | 53 | 3.96e-01 | -6.74e-02 | 0.993000 |
| REACTOME DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING | 61 | 3.96e-01 | 6.28e-02 | 0.993000 |
| REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE | 22 | 3.96e-01 | -1.05e-01 | 0.993000 |
| REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | 11 | 3.97e-01 | 1.48e-01 | 0.993000 |
| REACTOME METABOLISM OF COFACTORS | 19 | 3.97e-01 | -1.12e-01 | 0.993000 |
| REACTOME VIRAL MESSENGER RNA SYNTHESIS | 44 | 3.98e-01 | 7.37e-02 | 0.993000 |
| REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES | 39 | 3.98e-01 | -7.82e-02 | 0.993000 |
| REACTOME RIBAVIRIN ADME | 11 | 3.98e-01 | -1.47e-01 | 0.993000 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING | 6 | 3.98e-01 | 1.99e-01 | 0.993000 |
| REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | 15 | 3.98e-01 | 1.26e-01 | 0.993000 |
| REACTOME NECTIN NECL TRANS HETERODIMERIZATION | 7 | 4.02e-01 | -1.83e-01 | 0.993000 |
| REACTOME FRUCTOSE METABOLISM | 7 | 4.02e-01 | 1.83e-01 | 0.993000 |
| REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | 129 | 4.02e-01 | -4.27e-02 | 0.993000 |
| REACTOME SPRY REGULATION OF FGF SIGNALING | 16 | 4.03e-01 | 1.21e-01 | 0.993000 |
| REACTOME ACTIVATION OF C3 AND C5 | 6 | 4.04e-01 | -1.97e-01 | 0.993000 |
| REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION | 145 | 4.04e-01 | 4.02e-02 | 0.993000 |
| REACTOME SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS | 43 | 4.04e-01 | 7.36e-02 | 0.993000 |
| REACTOME ESR MEDIATED SIGNALING | 210 | 4.05e-01 | 3.34e-02 | 0.993000 |
| REACTOME MISCELLANEOUS SUBSTRATES | 12 | 4.05e-01 | 1.39e-01 | 0.993000 |
| REACTOME DEFECTIVE CHST14 CAUSES EDS MUSCULOCONTRACTURAL TYPE | 7 | 4.06e-01 | 1.81e-01 | 0.993000 |
| REACTOME UPTAKE AND ACTIONS OF BACTERIAL TOXINS | 28 | 4.07e-01 | -9.06e-02 | 0.993000 |
| REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS | 21 | 4.07e-01 | -1.05e-01 | 0.993000 |
| REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | 24 | 4.07e-01 | 9.78e-02 | 0.993000 |
| REACTOME FORMATION OF APOPTOSOME | 10 | 4.07e-01 | 1.51e-01 | 0.993000 |
| REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR4 | 14 | 4.08e-01 | 1.28e-01 | 0.993000 |
| REACTOME MITOTIC G2 G2 M PHASES | 194 | 4.09e-01 | -3.44e-02 | 0.993000 |
| REACTOME REGULATION OF PTEN MRNA TRANSLATION | 9 | 4.09e-01 | 1.59e-01 | 0.993000 |
| REACTOME BETA DEFENSINS | 27 | 4.09e-01 | 9.18e-02 | 0.993000 |
| REACTOME VITAMIN C ASCORBATE METABOLISM | 8 | 4.10e-01 | -1.68e-01 | 0.993000 |
| REACTOME SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL | 8 | 4.10e-01 | -1.68e-01 | 0.993000 |
| REACTOME INTEGRIN SIGNALING | 27 | 4.10e-01 | 9.15e-02 | 0.993000 |
| REACTOME PEROXISOMAL PROTEIN IMPORT | 62 | 4.13e-01 | 6.01e-02 | 0.994000 |
| REACTOME REGULATION OF FZD BY UBIQUITINATION | 21 | 4.15e-01 | -1.03e-01 | 0.994000 |
| REACTOME FRS MEDIATED FGFR2 SIGNALING | 24 | 4.15e-01 | 9.62e-02 | 0.994000 |
| REACTOME UPTAKE AND FUNCTION OF ANTHRAX TOXINS | 11 | 4.15e-01 | -1.42e-01 | 0.994000 |
| REACTOME PLATELET AGGREGATION PLUG FORMATION | 39 | 4.17e-01 | 7.51e-02 | 0.994000 |
| REACTOME PI5P REGULATES TP53 ACETYLATION | 9 | 4.18e-01 | -1.56e-01 | 0.994000 |
| REACTOME VITAMIN B1 THIAMIN METABOLISM | 5 | 4.20e-01 | -2.08e-01 | 0.994000 |
| REACTOME DNA REPAIR | 321 | 4.20e-01 | -2.62e-02 | 0.994000 |
| REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | 296 | 4.20e-01 | -2.72e-02 | 0.994000 |
| REACTOME VITAMIN D CALCIFEROL METABOLISM | 12 | 4.21e-01 | 1.34e-01 | 0.994000 |
| REACTOME BICARBONATE TRANSPORTERS | 10 | 4.21e-01 | 1.47e-01 | 0.994000 |
| REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY | 25 | 4.23e-01 | -9.25e-02 | 0.994000 |
| REACTOME PI3K EVENTS IN ERBB4 SIGNALING | 10 | 4.24e-01 | -1.46e-01 | 0.994000 |
| REACTOME POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION | 27 | 4.24e-01 | 8.89e-02 | 0.994000 |
| REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE | 52 | 4.24e-01 | 6.41e-02 | 0.994000 |
| REACTOME LINOLEIC ACID LA METABOLISM | 7 | 4.25e-01 | -1.74e-01 | 0.994000 |
| REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING | 32 | 4.25e-01 | 8.15e-02 | 0.994000 |
| REACTOME TLR3 MEDIATED TICAM1 DEPENDENT PROGRAMMED CELL DEATH | 6 | 4.26e-01 | -1.88e-01 | 0.994000 |
| REACTOME PHENYLALANINE METABOLISM | 6 | 4.27e-01 | -1.87e-01 | 0.994000 |
| REACTOME REGULATION OF TP53 ACTIVITY | 156 | 4.28e-01 | -3.68e-02 | 0.994000 |
| REACTOME ARYL HYDROCARBON RECEPTOR SIGNALLING | 6 | 4.29e-01 | 1.87e-01 | 0.994000 |
| REACTOME STABILIZATION OF P53 | 56 | 4.30e-01 | 6.10e-02 | 0.994000 |
| REACTOME INFLUENZA INFECTION | 149 | 4.30e-01 | 3.75e-02 | 0.994000 |
| REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | 160 | 4.30e-01 | -3.62e-02 | 0.994000 |
| REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | 32 | 4.31e-01 | -8.04e-02 | 0.994000 |
| REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS | 11 | 4.34e-01 | -1.36e-01 | 0.994000 |
| REACTOME METHIONINE SALVAGE PATHWAY | 6 | 4.34e-01 | -1.85e-01 | 0.994000 |
| REACTOME TAK1 DEPENDENT IKK AND NF KAPPA B ACTIVATION | 41 | 4.34e-01 | -7.07e-02 | 0.994000 |
| REACTOME KERATAN SULFATE KERATIN METABOLISM | 34 | 4.34e-01 | -7.76e-02 | 0.994000 |
| REACTOME IRON UPTAKE AND TRANSPORT | 56 | 4.34e-01 | -6.04e-02 | 0.994000 |
| REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE | 93 | 4.36e-01 | -4.68e-02 | 0.994000 |
| REACTOME TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS | 52 | 4.36e-01 | -6.24e-02 | 0.994000 |
| REACTOME DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX | 83 | 4.36e-01 | 4.94e-02 | 0.994000 |
| REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | 86 | 4.36e-01 | 4.86e-02 | 0.994000 |
| REACTOME PI 3K CASCADE FGFR2 | 22 | 4.36e-01 | 9.59e-02 | 0.994000 |
| REACTOME COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC | 52 | 4.37e-01 | -6.24e-02 | 0.994000 |
| REACTOME POLYMERASE SWITCHING | 13 | 4.37e-01 | -1.25e-01 | 0.994000 |
| REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | 19 | 4.37e-01 | -1.03e-01 | 0.994000 |
| REACTOME RUNX3 REGULATES BCL2L11 BIM TRANSCRIPTION | 5 | 4.37e-01 | 2.01e-01 | 0.994000 |
| REACTOME EGFR INTERACTS WITH PHOSPHOLIPASE C GAMMA | 9 | 4.37e-01 | -1.50e-01 | 0.994000 |
| REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | 15 | 4.37e-01 | 1.16e-01 | 0.994000 |
| REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS | 101 | 4.37e-01 | 4.47e-02 | 0.994000 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS | 121 | 4.38e-01 | 4.08e-02 | 0.994000 |
| REACTOME MISCELLANEOUS TRANSPORT AND BINDING EVENTS | 24 | 4.39e-01 | 9.13e-02 | 0.994000 |
| REACTOME TBC RABGAPS | 40 | 4.40e-01 | -7.05e-02 | 0.994000 |
| REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | 31 | 4.42e-01 | -7.98e-02 | 0.994000 |
| REACTOME MITOPHAGY | 28 | 4.43e-01 | 8.38e-02 | 0.994000 |
| REACTOME SIGNALING BY NTRK2 TRKB | 25 | 4.43e-01 | 8.86e-02 | 0.994000 |
| REACTOME THE ACTIVATION OF ARYLSULFATASES | 8 | 4.44e-01 | -1.56e-01 | 0.994000 |
| REACTOME MUSCLE CONTRACTION | 197 | 4.44e-01 | 3.17e-02 | 0.994000 |
| REACTOME SIGNALING BY FGFR IN DISEASE | 62 | 4.46e-01 | 5.60e-02 | 0.994000 |
| REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER | 28 | 4.46e-01 | 8.32e-02 | 0.994000 |
| REACTOME REGULATION BY C FLIP | 11 | 4.46e-01 | -1.33e-01 | 0.994000 |
| REACTOME HS GAG BIOSYNTHESIS | 28 | 4.51e-01 | -8.24e-02 | 0.994000 |
| REACTOME GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION | 14 | 4.51e-01 | -1.16e-01 | 0.994000 |
| REACTOME RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA | 7 | 4.51e-01 | 1.64e-01 | 0.994000 |
| REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON | 17 | 4.51e-01 | -1.06e-01 | 0.994000 |
| REACTOME CHROMOSOME MAINTENANCE | 130 | 4.51e-01 | 3.83e-02 | 0.994000 |
| REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | 35 | 4.52e-01 | -7.35e-02 | 0.994000 |
| REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR4 | 26 | 4.52e-01 | 8.52e-02 | 0.994000 |
| REACTOME SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS | 12 | 4.52e-01 | 1.25e-01 | 0.994000 |
| REACTOME METABOLISM OF NUCLEOTIDES | 94 | 4.53e-01 | -4.48e-02 | 0.994000 |
| REACTOME RHO GTPASES ACTIVATE CIT | 19 | 4.53e-01 | 9.94e-02 | 0.994000 |
| REACTOME HCMV INFECTION | 152 | 4.54e-01 | -3.52e-02 | 0.994000 |
| REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | 19 | 4.54e-01 | -9.92e-02 | 0.994000 |
| REACTOME PHASE 0 RAPID DEPOLARISATION | 31 | 4.55e-01 | 7.76e-02 | 0.994000 |
| REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | 11 | 4.55e-01 | 1.30e-01 | 0.994000 |
| REACTOME INTERLEUKIN 17 SIGNALING | 66 | 4.56e-01 | -5.31e-02 | 0.994000 |
| REACTOME CREB PHOSPHORYLATION | 6 | 4.56e-01 | -1.76e-01 | 0.994000 |
| REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | 122 | 4.56e-01 | -3.91e-02 | 0.994000 |
| REACTOME TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY | 16 | 4.56e-01 | -1.08e-01 | 0.994000 |
| REACTOME FORMATION OF AXIAL MESODERM | 14 | 4.56e-01 | -1.15e-01 | 0.994000 |
| REACTOME PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR | 21 | 4.57e-01 | -9.38e-02 | 0.994000 |
| REACTOME ONCOGENE INDUCED SENESCENCE | 35 | 4.57e-01 | 7.26e-02 | 0.994000 |
| REACTOME INTERFERON SIGNALING | 193 | 4.57e-01 | 3.10e-02 | 0.994000 |
| REACTOME INTERLEUKIN 23 SIGNALING | 9 | 4.58e-01 | -1.43e-01 | 0.994000 |
| REACTOME G PROTEIN BETA GAMMA SIGNALLING | 30 | 4.58e-01 | 7.83e-02 | 0.994000 |
| REACTOME DNA DAMAGE RECOGNITION IN GG NER | 36 | 4.58e-01 | -7.14e-02 | 0.994000 |
| REACTOME N GLYCAN TRIMMING AND ELONGATION IN THE CIS GOLGI | 5 | 4.60e-01 | 1.91e-01 | 0.994000 |
| REACTOME DISEASES OF MITOTIC CELL CYCLE | 37 | 4.60e-01 | -7.02e-02 | 0.994000 |
| REACTOME CONDENSATION OF PROMETAPHASE CHROMOSOMES | 11 | 4.60e-01 | -1.29e-01 | 0.994000 |
| REACTOME GPCR LIGAND BINDING | 444 | 4.61e-01 | -2.04e-02 | 0.994000 |
| REACTOME TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION | 5 | 4.62e-01 | -1.90e-01 | 0.995000 |
| REACTOME METAL ION SLC TRANSPORTERS | 23 | 4.63e-01 | -8.84e-02 | 0.996000 |
| REACTOME NETRIN 1 SIGNALING | 49 | 4.63e-01 | 6.05e-02 | 0.996000 |
| REACTOME DEFECTIVE LFNG CAUSES SCDO3 | 5 | 4.65e-01 | 1.89e-01 | 0.997000 |
| REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM | 45 | 4.66e-01 | -6.28e-02 | 0.997000 |
| REACTOME NEGATIVE REGULATION OF MET ACTIVITY | 20 | 4.67e-01 | -9.40e-02 | 0.997000 |
| REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | 37 | 4.68e-01 | -6.90e-02 | 0.997000 |
| REACTOME DISORDERS OF TRANSMEMBRANE TRANSPORTERS | 170 | 4.68e-01 | 3.23e-02 | 0.997000 |
| REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES | 77 | 4.69e-01 | -4.78e-02 | 0.997000 |
| REACTOME SHC1 EVENTS IN EGFR SIGNALING | 14 | 4.69e-01 | -1.12e-01 | 0.997000 |
| REACTOME FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES | 29 | 4.70e-01 | 7.75e-02 | 0.997000 |
| REACTOME DEFECTIVE F9 ACTIVATION | 5 | 4.70e-01 | -1.86e-01 | 0.997000 |
| REACTOME ROLE OF ABL IN ROBO SLIT SIGNALING | 8 | 4.71e-01 | -1.47e-01 | 0.997000 |
| REACTOME NEUROTRANSMITTER CLEARANCE | 9 | 4.71e-01 | -1.39e-01 | 0.997000 |
| REACTOME RHO GTPASE EFFECTORS | 305 | 4.74e-01 | 2.38e-02 | 0.997000 |
| REACTOME CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER | 25 | 4.74e-01 | 8.27e-02 | 0.997000 |
| REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES | 27 | 4.74e-01 | 7.95e-02 | 0.997000 |
| REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX | 9 | 4.75e-01 | -1.38e-01 | 0.997000 |
| REACTOME METALLOPROTEASE DUBS | 36 | 4.75e-01 | 6.88e-02 | 0.997000 |
| REACTOME DEGRADATION OF AXIN | 54 | 4.75e-01 | 5.62e-02 | 0.997000 |
| REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION | 60 | 4.77e-01 | 5.31e-02 | 0.997000 |
| REACTOME FRS MEDIATED FGFR3 SIGNALING | 19 | 4.77e-01 | 9.43e-02 | 0.997000 |
| REACTOME HIV INFECTION | 223 | 4.77e-01 | 2.76e-02 | 0.997000 |
| REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS | 16 | 4.77e-01 | 1.03e-01 | 0.997000 |
| REACTOME CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY | 25 | 4.77e-01 | -8.21e-02 | 0.997000 |
| REACTOME SIGNALING BY NUCLEAR RECEPTORS | 283 | 4.79e-01 | 2.44e-02 | 0.998000 |
| REACTOME CHL1 INTERACTIONS | 9 | 4.80e-01 | -1.36e-01 | 0.998000 |
| REACTOME PI3K AKT SIGNALING IN CANCER | 103 | 4.80e-01 | 4.02e-02 | 0.998000 |
| REACTOME RAC1 GTPASE CYCLE | 172 | 4.81e-01 | 3.12e-02 | 0.998000 |
| REACTOME AMINE LIGAND BINDING RECEPTORS | 40 | 4.81e-01 | 6.44e-02 | 0.998000 |
| REACTOME NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 24 | 4.81e-01 | 8.31e-02 | 0.998000 |
| REACTOME MYD88 INDEPENDENT TLR4 CASCADE | 103 | 4.82e-01 | -4.01e-02 | 0.998000 |
| REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES | 255 | 4.83e-01 | -2.55e-02 | 0.998000 |
| REACTOME KERATAN SULFATE BIOSYNTHESIS | 28 | 4.85e-01 | -7.63e-02 | 1.000000 |
| REACTOME MET RECEPTOR ACTIVATION | 6 | 4.85e-01 | -1.65e-01 | 1.000000 |
| REACTOME GLUCOSE METABOLISM | 90 | 4.86e-01 | -4.25e-02 | 1.000000 |
| REACTOME DNA REPLICATION | 178 | 4.86e-01 | 3.03e-02 | 1.000000 |
| REACTOME TRAFFICKING OF AMPA RECEPTORS | 29 | 4.86e-01 | 7.47e-02 | 1.000000 |
| REACTOME ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS | 5 | 4.88e-01 | -1.79e-01 | 1.000000 |
| REACTOME SELECTIVE AUTOPHAGY | 79 | 4.91e-01 | -4.48e-02 | 1.000000 |
| REACTOME DNA DAMAGE BYPASS | 47 | 4.91e-01 | -5.80e-02 | 1.000000 |
| REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | 17 | 4.92e-01 | -9.63e-02 | 1.000000 |
| REACTOME SCAVENGING BY CLASS B RECEPTORS | 6 | 4.93e-01 | 1.62e-01 | 1.000000 |
| REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | 16 | 4.93e-01 | 9.90e-02 | 1.000000 |
| REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS | 83 | 4.93e-01 | 4.35e-02 | 1.000000 |
| REACTOME DISEASES OF PROGRAMMED CELL DEATH | 96 | 4.94e-01 | 4.04e-02 | 1.000000 |
| REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY | 26 | 4.96e-01 | 7.70e-02 | 1.000000 |
| REACTOME AMINO ACIDS REGULATE MTORC1 | 53 | 4.97e-01 | 5.39e-02 | 1.000000 |
| REACTOME SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS | 74 | 4.98e-01 | 4.56e-02 | 1.000000 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3 | 11 | 4.98e-01 | 1.18e-01 | 1.000000 |
| REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS | 299 | 4.99e-01 | 2.28e-02 | 1.000000 |
| REACTOME SIGNALING BY GPCR | 673 | 5.00e-01 | 1.52e-02 | 1.000000 |
| REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY | 33 | 5.01e-01 | 6.77e-02 | 1.000000 |
| REACTOME HDR THROUGH MMEJ ALT NHEJ | 12 | 5.02e-01 | -1.12e-01 | 1.000000 |
| REACTOME PI 3K CASCADE FGFR3 | 17 | 5.04e-01 | 9.37e-02 | 1.000000 |
| REACTOME GAP JUNCTION DEGRADATION | 12 | 5.04e-01 | -1.11e-01 | 1.000000 |
| REACTOME REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR | 11 | 5.04e-01 | 1.16e-01 | 1.000000 |
| REACTOME ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN | 13 | 5.04e-01 | 1.07e-01 | 1.000000 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN | 13 | 5.05e-01 | -1.07e-01 | 1.000000 |
| REACTOME NUCLEAR ENVELOPE NE REASSEMBLY | 74 | 5.07e-01 | -4.46e-02 | 1.000000 |
| REACTOME REGULATION OF GENE EXPRESSION IN ENDOCRINE COMMITTED NEUROG3 PROGENITOR CELLS | 5 | 5.07e-01 | 1.71e-01 | 1.000000 |
| REACTOME SMAC XIAP REGULATED APOPTOTIC RESPONSE | 7 | 5.08e-01 | 1.44e-01 | 1.000000 |
| REACTOME COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC | 98 | 5.09e-01 | -3.86e-02 | 1.000000 |
| REACTOME RRNA PROCESSING IN THE MITOCHONDRION | 9 | 5.10e-01 | 1.27e-01 | 1.000000 |
| REACTOME MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION | 15 | 5.11e-01 | -9.81e-02 | 1.000000 |
| REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | 80 | 5.11e-01 | 4.25e-02 | 1.000000 |
| REACTOME VLDL ASSEMBLY | 5 | 5.11e-01 | 1.70e-01 | 1.000000 |
| REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | 53 | 5.12e-01 | 5.21e-02 | 1.000000 |
| REACTOME CLATHRIN MEDIATED ENDOCYTOSIS | 139 | 5.12e-01 | -3.22e-02 | 1.000000 |
| REACTOME CYCLIN D ASSOCIATED EVENTS IN G1 | 46 | 5.12e-01 | 5.58e-02 | 1.000000 |
| REACTOME INTERLEUKIN 7 SIGNALING | 31 | 5.13e-01 | 6.79e-02 | 1.000000 |
| REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS | 68 | 5.13e-01 | 4.59e-02 | 1.000000 |
| REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | 7 | 5.14e-01 | 1.43e-01 | 1.000000 |
| REACTOME FLT3 SIGNALING BY CBL MUTANTS | 7 | 5.16e-01 | 1.42e-01 | 1.000000 |
| REACTOME HEME BIOSYNTHESIS | 13 | 5.16e-01 | -1.04e-01 | 1.000000 |
| REACTOME INFECTION WITH MYCOBACTERIUM TUBERCULOSIS | 25 | 5.16e-01 | -7.51e-02 | 1.000000 |
| REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1 | 20 | 5.17e-01 | 8.36e-02 | 1.000000 |
| REACTOME SUMOYLATION OF UBIQUITINYLATION PROTEINS | 39 | 5.19e-01 | 5.96e-02 | 1.000000 |
| REACTOME NEGATIVE REGULATION OF FLT3 | 15 | 5.20e-01 | 9.59e-02 | 1.000000 |
| REACTOME SIGNALING BY NOTCH4 | 80 | 5.21e-01 | 4.15e-02 | 1.000000 |
| REACTOME JOSEPHIN DOMAIN DUBS | 11 | 5.21e-01 | -1.12e-01 | 1.000000 |
| REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | 14 | 5.22e-01 | -9.89e-02 | 1.000000 |
| REACTOME CELL CYCLE CHECKPOINTS | 284 | 5.22e-01 | -2.21e-02 | 1.000000 |
| REACTOME MRNA EDITING C TO U CONVERSION | 8 | 5.22e-01 | 1.31e-01 | 1.000000 |
| REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | 17 | 5.22e-01 | -8.96e-02 | 1.000000 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS | 5 | 5.23e-01 | -1.65e-01 | 1.000000 |
| REACTOME INTERLEUKIN 1 FAMILY SIGNALING | 146 | 5.25e-01 | -3.05e-02 | 1.000000 |
| REACTOME FORMATION OF INCISION COMPLEX IN GG NER | 40 | 5.26e-01 | -5.79e-02 | 1.000000 |
| REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A | 26 | 5.26e-01 | 7.18e-02 | 1.000000 |
| REACTOME RND3 GTPASE CYCLE | 41 | 5.26e-01 | -5.72e-02 | 1.000000 |
| REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1 | 229 | 5.28e-01 | -2.42e-02 | 1.000000 |
| REACTOME CHREBP ACTIVATES METABOLIC GENE EXPRESSION | 8 | 5.28e-01 | -1.29e-01 | 1.000000 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES | 49 | 5.28e-01 | -5.21e-02 | 1.000000 |
| REACTOME STAT3 NUCLEAR EVENTS DOWNSTREAM OF ALK SIGNALING | 9 | 5.28e-01 | -1.21e-01 | 1.000000 |
| REACTOME NETRIN MEDIATED REPULSION SIGNALS | 8 | 5.28e-01 | 1.29e-01 | 1.000000 |
| REACTOME SIGNALING BY NTRK3 TRKC | 17 | 5.29e-01 | 8.83e-02 | 1.000000 |
| REACTOME SYNTHESIS OF PI | 5 | 5.30e-01 | 1.62e-01 | 1.000000 |
| REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION | 23 | 5.31e-01 | 7.55e-02 | 1.000000 |
| REACTOME GRB2 EVENTS IN ERBB2 SIGNALING | 16 | 5.32e-01 | -9.03e-02 | 1.000000 |
| REACTOME SHC MEDIATED CASCADE FGFR4 | 19 | 5.32e-01 | 8.27e-02 | 1.000000 |
| REACTOME CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA | 63 | 5.32e-01 | -4.55e-02 | 1.000000 |
| REACTOME RHOBTB2 GTPASE CYCLE | 22 | 5.33e-01 | -7.67e-02 | 1.000000 |
| REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | 14 | 5.33e-01 | -9.61e-02 | 1.000000 |
| REACTOME RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS | 5 | 5.35e-01 | -1.60e-01 | 1.000000 |
| REACTOME SERINE BIOSYNTHESIS | 9 | 5.36e-01 | -1.19e-01 | 1.000000 |
| REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | 29 | 5.37e-01 | 6.62e-02 | 1.000000 |
| REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING | 29 | 5.38e-01 | 6.60e-02 | 1.000000 |
| REACTOME NS1 MEDIATED EFFECTS ON HOST PATHWAYS | 41 | 5.39e-01 | -5.55e-02 | 1.000000 |
| REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS | 418 | 5.39e-01 | 1.75e-02 | 1.000000 |
| REACTOME EICOSANOIDS | 12 | 5.39e-01 | 1.02e-01 | 1.000000 |
| REACTOME SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER | 54 | 5.41e-01 | 4.81e-02 | 1.000000 |
| REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | 15 | 5.42e-01 | -9.10e-02 | 1.000000 |
| REACTOME LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME | 11 | 5.42e-01 | -1.06e-01 | 1.000000 |
| REACTOME OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS | 8 | 5.42e-01 | 1.25e-01 | 1.000000 |
| REACTOME COLLAGEN DEGRADATION | 61 | 5.42e-01 | 4.51e-02 | 1.000000 |
| REACTOME INTERLEUKIN 20 FAMILY SIGNALING | 25 | 5.43e-01 | 7.03e-02 | 1.000000 |
| REACTOME CHAPERONE MEDIATED AUTOPHAGY | 20 | 5.44e-01 | 7.83e-02 | 1.000000 |
| REACTOME INDUCTION OF CELL CELL FUSION | 12 | 5.45e-01 | 1.01e-01 | 1.000000 |
| REACTOME KINESINS | 59 | 5.45e-01 | -4.55e-02 | 1.000000 |
| REACTOME DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE | 76 | 5.45e-01 | 4.01e-02 | 1.000000 |
| REACTOME FGFRL1 MODULATION OF FGFR1 SIGNALING | 13 | 5.46e-01 | 9.67e-02 | 1.000000 |
| REACTOME INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE | 20 | 5.46e-01 | -7.80e-02 | 1.000000 |
| REACTOME TRANSCRIPTIONAL REGULATION BY MECP2 | 60 | 5.46e-01 | -4.50e-02 | 1.000000 |
| REACTOME LGI ADAM INTERACTIONS | 14 | 5.47e-01 | -9.30e-02 | 1.000000 |
| REACTOME TRANSPORT OF FATTY ACIDS | 8 | 5.47e-01 | 1.23e-01 | 1.000000 |
| REACTOME PROCESSING OF DNA DOUBLE STRAND BREAK ENDS | 93 | 5.47e-01 | -3.61e-02 | 1.000000 |
| REACTOME ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY | 10 | 5.47e-01 | 1.10e-01 | 1.000000 |
| REACTOME REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS | 14 | 5.48e-01 | -9.28e-02 | 1.000000 |
| REACTOME MULTIFUNCTIONAL ANION EXCHANGERS | 9 | 5.50e-01 | -1.15e-01 | 1.000000 |
| REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2 | 17 | 5.51e-01 | 8.36e-02 | 1.000000 |
| REACTOME RHOQ GTPASE CYCLE | 57 | 5.51e-01 | -4.57e-02 | 1.000000 |
| REACTOME TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE | 10 | 5.51e-01 | -1.09e-01 | 1.000000 |
| REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | 38 | 5.51e-01 | 5.59e-02 | 1.000000 |
| REACTOME BASE EXCISION REPAIR AP SITE FORMATION | 59 | 5.52e-01 | 4.47e-02 | 1.000000 |
| REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR2 | 29 | 5.53e-01 | 6.37e-02 | 1.000000 |
| REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | 76 | 5.55e-01 | 3.92e-02 | 1.000000 |
| REACTOME RND2 GTPASE CYCLE | 42 | 5.55e-01 | -5.26e-02 | 1.000000 |
| REACTOME CONDENSATION OF PROPHASE CHROMOSOMES | 66 | 5.56e-01 | 4.19e-02 | 1.000000 |
| REACTOME SCAVENGING OF HEME FROM PLASMA | 13 | 5.56e-01 | 9.42e-02 | 1.000000 |
| REACTOME CRISTAE FORMATION | 27 | 5.58e-01 | -6.52e-02 | 1.000000 |
| REACTOME CELLULAR SENESCENCE | 189 | 5.59e-01 | 2.46e-02 | 1.000000 |
| REACTOME PRC2 METHYLATES HISTONES AND DNA | 65 | 5.60e-01 | 4.18e-02 | 1.000000 |
| REACTOME RIPK1 MEDIATED REGULATED NECROSIS | 30 | 5.60e-01 | -6.15e-02 | 1.000000 |
| REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | 38 | 5.60e-01 | 5.47e-02 | 1.000000 |
| REACTOME IRAK1 RECRUITS IKK COMPLEX | 12 | 5.60e-01 | 9.71e-02 | 1.000000 |
| REACTOME FGFR3B LIGAND BINDING AND ACTIVATION | 7 | 5.61e-01 | 1.27e-01 | 1.000000 |
| REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE | 9 | 5.62e-01 | -1.12e-01 | 1.000000 |
| REACTOME EXTRA NUCLEAR ESTROGEN SIGNALING | 74 | 5.63e-01 | 3.89e-02 | 1.000000 |
| REACTOME SARS COV 2 MODULATES AUTOPHAGY | 11 | 5.64e-01 | 1.01e-01 | 1.000000 |
| REACTOME MAPK3 ERK1 ACTIVATION | 10 | 5.64e-01 | 1.05e-01 | 1.000000 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE | 20 | 5.65e-01 | 7.44e-02 | 1.000000 |
| REACTOME RSK ACTIVATION | 5 | 5.65e-01 | 1.49e-01 | 1.000000 |
| REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | 36 | 5.67e-01 | -5.51e-02 | 1.000000 |
| REACTOME SYNTHESIS OF PG | 8 | 5.67e-01 | -1.17e-01 | 1.000000 |
| REACTOME CELLULAR RESPONSE TO HEAT STRESS | 99 | 5.67e-01 | 3.33e-02 | 1.000000 |
| REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS | 83 | 5.68e-01 | -3.63e-02 | 1.000000 |
| REACTOME TRNA MODIFICATION IN THE MITOCHONDRION | 8 | 5.69e-01 | 1.16e-01 | 1.000000 |
| REACTOME MET ACTIVATES PI3K AKT SIGNALING | 6 | 5.69e-01 | -1.34e-01 | 1.000000 |
| REACTOME ACYL CHAIN REMODELLING OF PE | 29 | 5.70e-01 | 6.10e-02 | 1.000000 |
| REACTOME REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS | 15 | 5.70e-01 | -8.47e-02 | 1.000000 |
| REACTOME PTEN REGULATION | 135 | 5.71e-01 | 2.83e-02 | 1.000000 |
| REACTOME SIGNALING BY HIPPO | 19 | 5.71e-01 | -7.51e-02 | 1.000000 |
| REACTOME ALPHA DEFENSINS | 6 | 5.71e-01 | -1.33e-01 | 1.000000 |
| REACTOME PYRIMIDINE SALVAGE | 10 | 5.72e-01 | -1.03e-01 | 1.000000 |
| REACTOME CREB3 FACTORS ACTIVATE GENES | 8 | 5.73e-01 | 1.15e-01 | 1.000000 |
| REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | 15 | 5.74e-01 | 8.39e-02 | 1.000000 |
| REACTOME SUPPRESSION OF APOPTOSIS | 7 | 5.74e-01 | -1.23e-01 | 1.000000 |
| REACTOME REGULATION OF INSULIN SECRETION | 77 | 5.74e-01 | 3.71e-02 | 1.000000 |
| REACTOME MATURATION OF SARS COV 2 SPIKE PROTEIN | 35 | 5.74e-01 | -5.49e-02 | 1.000000 |
| REACTOME FATTY ACYL COA BIOSYNTHESIS | 36 | 5.75e-01 | 5.41e-02 | 1.000000 |
| REACTOME METALLOTHIONEINS BIND METALS | 11 | 5.75e-01 | -9.77e-02 | 1.000000 |
| REACTOME REGULATION OF TP53 EXPRESSION AND DEGRADATION | 37 | 5.77e-01 | 5.30e-02 | 1.000000 |
| REACTOME NICOTINAMIDE SALVAGING | 19 | 5.78e-01 | 7.37e-02 | 1.000000 |
| REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 | 54 | 5.79e-01 | 4.37e-02 | 1.000000 |
| REACTOME DEGRADATION OF GLI1 BY THE PROTEASOME | 59 | 5.79e-01 | 4.17e-02 | 1.000000 |
| REACTOME RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA | 27 | 5.80e-01 | -6.16e-02 | 1.000000 |
| REACTOME INTERLEUKIN RECEPTOR SHC SIGNALING | 24 | 5.80e-01 | 6.53e-02 | 1.000000 |
| REACTOME SIGNALING BY NOTCH3 | 48 | 5.81e-01 | 4.61e-02 | 1.000000 |
| REACTOME RAP1 SIGNALLING | 16 | 5.82e-01 | -7.96e-02 | 1.000000 |
| REACTOME SUMOYLATION OF DNA REPLICATION PROTEINS | 46 | 5.82e-01 | 4.69e-02 | 1.000000 |
| REACTOME GOLGI TO ER RETROGRADE TRANSPORT | 132 | 5.82e-01 | -2.77e-02 | 1.000000 |
| REACTOME PHENYLALANINE AND TYROSINE METABOLISM | 11 | 5.83e-01 | -9.57e-02 | 1.000000 |
| REACTOME PTK6 EXPRESSION | 5 | 5.83e-01 | 1.42e-01 | 1.000000 |
| REACTOME GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION | 42 | 5.84e-01 | 4.88e-02 | 1.000000 |
| REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | 17 | 5.84e-01 | -7.67e-02 | 1.000000 |
| REACTOME MITOCHONDRIAL PROTEIN IMPORT | 58 | 5.84e-01 | -4.15e-02 | 1.000000 |
| REACTOME NOSTRIN MEDIATED ENOS TRAFFICKING | 5 | 5.85e-01 | 1.41e-01 | 1.000000 |
| REACTOME ATTACHMENT AND ENTRY | 16 | 5.85e-01 | -7.88e-02 | 1.000000 |
| REACTOME EARLY SARS COV 2 INFECTION EVENTS | 34 | 5.85e-01 | -5.41e-02 | 1.000000 |
| REACTOME G2 M CHECKPOINTS | 162 | 5.85e-01 | -2.48e-02 | 1.000000 |
| REACTOME LATE ENDOSOMAL MICROAUTOPHAGY | 33 | 5.89e-01 | -5.43e-02 | 1.000000 |
| REACTOME MYOGENESIS | 29 | 5.90e-01 | -5.78e-02 | 1.000000 |
| REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | 20 | 5.91e-01 | -6.94e-02 | 1.000000 |
| REACTOME SIGNALLING TO RAS | 20 | 5.93e-01 | 6.90e-02 | 1.000000 |
| REACTOME SUMOYLATION OF INTRACELLULAR RECEPTORS | 29 | 5.93e-01 | 5.73e-02 | 1.000000 |
| REACTOME PP2A MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS | 6 | 5.94e-01 | 1.26e-01 | 1.000000 |
| REACTOME PLASMA LIPOPROTEIN CLEARANCE | 37 | 5.94e-01 | 5.07e-02 | 1.000000 |
| REACTOME RUNX3 REGULATES CDKN1A TRANSCRIPTION | 7 | 5.94e-01 | 1.16e-01 | 1.000000 |
| REACTOME POLO LIKE KINASE MEDIATED EVENTS | 16 | 5.94e-01 | -7.69e-02 | 1.000000 |
| REACTOME SLC TRANSPORTER DISORDERS | 94 | 5.94e-01 | 3.18e-02 | 1.000000 |
| REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | 19 | 5.96e-01 | -7.03e-02 | 1.000000 |
| REACTOME AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA | 54 | 5.97e-01 | 4.16e-02 | 1.000000 |
| REACTOME FCGR ACTIVATION | 11 | 5.97e-01 | 9.21e-02 | 1.000000 |
| REACTOME CAMK IV MEDIATED PHOSPHORYLATION OF CREB | 10 | 5.98e-01 | 9.63e-02 | 1.000000 |
| REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | 26 | 5.98e-01 | -5.98e-02 | 1.000000 |
| REACTOME SIGNALING BY FGFR3 | 39 | 5.98e-01 | 4.88e-02 | 1.000000 |
| REACTOME CRMPS IN SEMA3A SIGNALING | 15 | 5.98e-01 | -7.86e-02 | 1.000000 |
| REACTOME ERK MAPK TARGETS | 20 | 5.99e-01 | -6.80e-02 | 1.000000 |
| REACTOME DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA | 77 | 5.99e-01 | -3.47e-02 | 1.000000 |
| REACTOME SIGNALING BY ERBB2 IN CANCER | 26 | 6.00e-01 | -5.94e-02 | 1.000000 |
| REACTOME LRR FLII INTERACTING PROTEIN 1 LRRFIP1 ACTIVATES TYPE I IFN PRODUCTION | 5 | 6.01e-01 | -1.35e-01 | 1.000000 |
| REACTOME CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION | 11 | 6.01e-01 | -9.10e-02 | 1.000000 |
| REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS | 6 | 6.02e-01 | 1.23e-01 | 1.000000 |
| REACTOME ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION | 16 | 6.03e-01 | -7.51e-02 | 1.000000 |
| REACTOME SPHINGOLIPID METABOLISM | 84 | 6.04e-01 | 3.28e-02 | 1.000000 |
| REACTOME RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION | 8 | 6.04e-01 | 1.06e-01 | 1.000000 |
| REACTOME HATS ACETYLATE HISTONES | 129 | 6.05e-01 | 2.64e-02 | 1.000000 |
| REACTOME ROBO RECEPTORS BIND AKAP5 | 9 | 6.06e-01 | -9.94e-02 | 1.000000 |
| REACTOME ORC1 REMOVAL FROM CHROMATIN | 70 | 6.06e-01 | 3.57e-02 | 1.000000 |
| REACTOME SYNTHESIS OF KETONE BODIES | 8 | 6.06e-01 | -1.05e-01 | 1.000000 |
| REACTOME HEDGEHOG LIGAND BIOGENESIS | 64 | 6.06e-01 | 3.72e-02 | 1.000000 |
| REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL | 58 | 6.07e-01 | -3.91e-02 | 1.000000 |
| REACTOME REGULATION OF BETA CELL DEVELOPMENT | 41 | 6.07e-01 | -4.64e-02 | 1.000000 |
| REACTOME TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS | 82 | 6.08e-01 | 3.28e-02 | 1.000000 |
| REACTOME STAT5 ACTIVATION | 7 | 6.09e-01 | -1.12e-01 | 1.000000 |
| REACTOME RESPONSE OF MTB TO PHAGOCYTOSIS | 22 | 6.09e-01 | -6.30e-02 | 1.000000 |
| REACTOME REGULATION OF PTEN LOCALIZATION | 8 | 6.09e-01 | 1.04e-01 | 1.000000 |
| REACTOME INTERLEUKIN 1 SIGNALING | 110 | 6.11e-01 | -2.81e-02 | 1.000000 |
| REACTOME MET ACTIVATES PTPN11 | 5 | 6.11e-01 | -1.31e-01 | 1.000000 |
| REACTOME INFECTIOUS DISEASE | 910 | 6.12e-01 | 9.92e-03 | 1.000000 |
| REACTOME FGFR2B LIGAND BINDING AND ACTIVATION | 10 | 6.12e-01 | 9.27e-02 | 1.000000 |
| REACTOME DEFENSINS | 33 | 6.13e-01 | 5.08e-02 | 1.000000 |
| REACTOME SIGNALING BY RNF43 MUTANTS | 8 | 6.13e-01 | 1.03e-01 | 1.000000 |
| REACTOME RHOV GTPASE CYCLE | 36 | 6.14e-01 | -4.86e-02 | 1.000000 |
| REACTOME GRB7 EVENTS IN ERBB2 SIGNALING | 5 | 6.14e-01 | -1.30e-01 | 1.000000 |
| REACTOME REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS | 11 | 6.15e-01 | -8.76e-02 | 1.000000 |
| REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | 14 | 6.16e-01 | -7.74e-02 | 1.000000 |
| REACTOME BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA | 5 | 6.18e-01 | -1.29e-01 | 1.000000 |
| REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12 | 22 | 6.18e-01 | -6.15e-02 | 1.000000 |
| REACTOME RHOF GTPASE CYCLE | 40 | 6.18e-01 | -4.56e-02 | 1.000000 |
| REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS | 63 | 6.18e-01 | 3.63e-02 | 1.000000 |
| REACTOME METABOLISM OF PORPHYRINS | 26 | 6.20e-01 | -5.62e-02 | 1.000000 |
| REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE | 5 | 6.20e-01 | 1.28e-01 | 1.000000 |
| REACTOME SUMOYLATION OF DNA METHYLATION PROTEINS | 16 | 6.21e-01 | 7.14e-02 | 1.000000 |
| REACTOME DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE | 30 | 6.22e-01 | 5.20e-02 | 1.000000 |
| REACTOME CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT | 19 | 6.23e-01 | -6.52e-02 | 1.000000 |
| REACTOME FRS MEDIATED FGFR1 SIGNALING | 23 | 6.23e-01 | 5.92e-02 | 1.000000 |
| REACTOME CYTOPROTECTION BY HMOX1 | 59 | 6.23e-01 | -3.70e-02 | 1.000000 |
| REACTOME ABC TRANSPORTER DISORDERS | 76 | 6.23e-01 | 3.26e-02 | 1.000000 |
| REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | 10 | 6.25e-01 | 8.93e-02 | 1.000000 |
| REACTOME AMYLOID FIBER FORMATION | 102 | 6.27e-01 | 2.79e-02 | 1.000000 |
| REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES | 11 | 6.27e-01 | 8.46e-02 | 1.000000 |
| REACTOME BETA OXIDATION OF PRISTANOYL COA | 9 | 6.27e-01 | 9.35e-02 | 1.000000 |
| REACTOME CIRCADIAN CLOCK | 68 | 6.28e-01 | -3.40e-02 | 1.000000 |
| REACTOME TIGHT JUNCTION INTERACTIONS | 29 | 6.29e-01 | 5.19e-02 | 1.000000 |
| REACTOME DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1 | 9 | 6.29e-01 | -9.30e-02 | 1.000000 |
| REACTOME PHOSPHORYLATION OF THE APC C | 20 | 6.31e-01 | -6.20e-02 | 1.000000 |
| REACTOME SIGNALING BY NTRKS | 132 | 6.31e-01 | -2.42e-02 | 1.000000 |
| REACTOME PROTEIN METHYLATION | 17 | 6.31e-01 | -6.72e-02 | 1.000000 |
| REACTOME DAG AND IP3 SIGNALING | 40 | 6.32e-01 | -4.38e-02 | 1.000000 |
| REACTOME TOLL LIKE RECEPTOR 9 TLR9 CASCADE | 100 | 6.32e-01 | -2.77e-02 | 1.000000 |
| REACTOME MAP2K AND MAPK ACTIVATION | 38 | 6.32e-01 | 4.49e-02 | 1.000000 |
| REACTOME EXTRACELLULAR MATRIX ORGANIZATION | 291 | 6.33e-01 | -1.63e-02 | 1.000000 |
| REACTOME CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2 | 11 | 6.33e-01 | 8.30e-02 | 1.000000 |
| REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT | 159 | 6.36e-01 | -2.17e-02 | 1.000000 |
| REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR3 | 24 | 6.38e-01 | 5.55e-02 | 1.000000 |
| REACTOME REDUCTION OF CYTOSOLIC CA LEVELS | 11 | 6.38e-01 | 8.18e-02 | 1.000000 |
| REACTOME NEUROTRANSMITTER RELEASE CYCLE | 48 | 6.39e-01 | -3.92e-02 | 1.000000 |
| REACTOME SIGNALING BY FGFR1 IN DISEASE | 38 | 6.39e-01 | -4.40e-02 | 1.000000 |
| REACTOME FLT3 SIGNALING IN DISEASE | 28 | 6.39e-01 | -5.12e-02 | 1.000000 |
| REACTOME MET RECEPTOR RECYCLING | 10 | 6.39e-01 | -8.57e-02 | 1.000000 |
| REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS | 60 | 6.40e-01 | 3.49e-02 | 1.000000 |
| REACTOME COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING | 38 | 6.40e-01 | 4.38e-02 | 1.000000 |
| REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | 30 | 6.40e-01 | -4.93e-02 | 1.000000 |
| REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR | 79 | 6.40e-01 | 3.04e-02 | 1.000000 |
| REACTOME NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 11 | 6.40e-01 | 8.14e-02 | 1.000000 |
| REACTOME HOST INTERACTIONS OF HIV FACTORS | 127 | 6.41e-01 | 2.40e-02 | 1.000000 |
| REACTOME RHOC GTPASE CYCLE | 71 | 6.43e-01 | 3.18e-02 | 1.000000 |
| REACTOME TRAF6 MEDIATED NF KB ACTIVATION | 24 | 6.45e-01 | -5.44e-02 | 1.000000 |
| REACTOME ANTIGEN PROCESSING CROSS PRESENTATION | 98 | 6.46e-01 | 2.69e-02 | 1.000000 |
| REACTOME POTASSIUM CHANNELS | 102 | 6.46e-01 | -2.64e-02 | 1.000000 |
| REACTOME BIOLOGICAL OXIDATIONS | 210 | 6.46e-01 | -1.84e-02 | 1.000000 |
| REACTOME REGULATION OF TP53 ACTIVITY THROUGH METHYLATION | 19 | 6.48e-01 | 6.04e-02 | 1.000000 |
| REACTOME PURINE CATABOLISM | 17 | 6.49e-01 | 6.39e-02 | 1.000000 |
| REACTOME TRANSCRIPTIONAL REGULATION BY E2F6 | 32 | 6.49e-01 | -4.66e-02 | 1.000000 |
| REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING | 12 | 6.49e-01 | -7.58e-02 | 1.000000 |
| REACTOME CELL JUNCTION ORGANIZATION | 89 | 6.49e-01 | 2.79e-02 | 1.000000 |
| REACTOME GLYCOGEN STORAGE DISEASES | 15 | 6.50e-01 | -6.77e-02 | 1.000000 |
| REACTOME NEUREXINS AND NEUROLIGINS | 51 | 6.50e-01 | -3.68e-02 | 1.000000 |
| REACTOME CALCITONIN LIKE LIGAND RECEPTORS | 10 | 6.50e-01 | 8.29e-02 | 1.000000 |
| REACTOME M PHASE | 398 | 6.51e-01 | -1.32e-02 | 1.000000 |
| REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | 14 | 6.51e-01 | 6.98e-02 | 1.000000 |
| REACTOME NUCLEAR SIGNALING BY ERBB4 | 32 | 6.52e-01 | -4.60e-02 | 1.000000 |
| REACTOME PHASE 4 RESTING MEMBRANE POTENTIAL | 19 | 6.52e-01 | -5.97e-02 | 1.000000 |
| REACTOME CHOLINE CATABOLISM | 6 | 6.52e-01 | 1.06e-01 | 1.000000 |
| REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | 21 | 6.54e-01 | 5.65e-02 | 1.000000 |
| REACTOME INTEGRATION OF ENERGY METABOLISM | 105 | 6.54e-01 | -2.53e-02 | 1.000000 |
| REACTOME G ALPHA Z SIGNALLING EVENTS | 48 | 6.55e-01 | 3.73e-02 | 1.000000 |
| REACTOME O LINKED GLYCOSYLATION | 109 | 6.55e-01 | -2.48e-02 | 1.000000 |
| REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG | 7 | 6.55e-01 | 9.75e-02 | 1.000000 |
| REACTOME ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS | 11 | 6.55e-01 | 7.77e-02 | 1.000000 |
| REACTOME UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION | 19 | 6.56e-01 | -5.90e-02 | 1.000000 |
| REACTOME SARS COV 1 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS | 16 | 6.59e-01 | -6.37e-02 | 1.000000 |
| REACTOME P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1 | 6 | 6.60e-01 | 1.04e-01 | 1.000000 |
| REACTOME GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION | 7 | 6.60e-01 | 9.59e-02 | 1.000000 |
| REACTOME PI 3K CASCADE FGFR1 | 21 | 6.60e-01 | 5.54e-02 | 1.000000 |
| REACTOME SIGNALING BY VEGF | 102 | 6.61e-01 | 2.51e-02 | 1.000000 |
| REACTOME SIGNALING BY CSF3 G CSF | 30 | 6.62e-01 | 4.62e-02 | 1.000000 |
| REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | 29 | 6.62e-01 | 4.69e-02 | 1.000000 |
| REACTOME MATURATION OF SARS COV 2 NUCLEOPROTEIN | 15 | 6.62e-01 | 6.52e-02 | 1.000000 |
| REACTOME GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | 34 | 6.63e-01 | -4.32e-02 | 1.000000 |
| REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING | 45 | 6.63e-01 | 3.75e-02 | 1.000000 |
| REACTOME GLYCOGEN METABOLISM | 22 | 6.63e-01 | 5.36e-02 | 1.000000 |
| REACTOME PEXOPHAGY | 11 | 6.63e-01 | 7.58e-02 | 1.000000 |
| REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | 66 | 6.64e-01 | 3.09e-02 | 1.000000 |
| REACTOME REGULATED PROTEOLYSIS OF P75NTR | 11 | 6.64e-01 | 7.56e-02 | 1.000000 |
| REACTOME OPIOID SIGNALLING | 89 | 6.65e-01 | -2.65e-02 | 1.000000 |
| REACTOME METABOLISM OF LIPIDS | 709 | 6.67e-01 | -9.47e-03 | 1.000000 |
| REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION | 89 | 6.67e-01 | -2.64e-02 | 1.000000 |
| REACTOME ACTIVATION OF MATRIX METALLOPROTEINASES | 30 | 6.68e-01 | -4.53e-02 | 1.000000 |
| REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | 48 | 6.68e-01 | 3.58e-02 | 1.000000 |
| REACTOME SIGNALING BY NOTCH2 | 32 | 6.68e-01 | 4.38e-02 | 1.000000 |
| REACTOME ECM PROTEOGLYCANS | 73 | 6.68e-01 | 2.90e-02 | 1.000000 |
| REACTOME SYNDECAN INTERACTIONS | 26 | 6.69e-01 | 4.84e-02 | 1.000000 |
| REACTOME INTERFERON GAMMA SIGNALING | 88 | 6.69e-01 | 2.63e-02 | 1.000000 |
| REACTOME UREA CYCLE | 9 | 6.69e-01 | -8.22e-02 | 1.000000 |
| REACTOME ERYTHROPOIETIN ACTIVATES STAT5 | 7 | 6.70e-01 | -9.30e-02 | 1.000000 |
| REACTOME TIE2 SIGNALING | 18 | 6.70e-01 | -5.80e-02 | 1.000000 |
| REACTOME FCERI MEDIATED NF KB ACTIVATION | 78 | 6.71e-01 | 2.78e-02 | 1.000000 |
| REACTOME IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS | 17 | 6.71e-01 | 5.94e-02 | 1.000000 |
| REACTOME SIGNALING BY ACTIVIN | 15 | 6.72e-01 | -6.32e-02 | 1.000000 |
| REACTOME COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM | 21 | 6.72e-01 | 5.34e-02 | 1.000000 |
| REACTOME RECEPTOR MEDIATED MITOPHAGY | 10 | 6.73e-01 | 7.70e-02 | 1.000000 |
| REACTOME DISINHIBITION OF SNARE FORMATION | 5 | 6.75e-01 | -1.08e-01 | 1.000000 |
| REACTOME TRIGLYCERIDE BIOSYNTHESIS | 12 | 6.76e-01 | 6.97e-02 | 1.000000 |
| REACTOME RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION | 22 | 6.77e-01 | -5.13e-02 | 1.000000 |
| REACTOME NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 22 | 6.77e-01 | 5.12e-02 | 1.000000 |
| REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1 | 31 | 6.78e-01 | 4.30e-02 | 1.000000 |
| REACTOME UB SPECIFIC PROCESSING PROTEASES | 187 | 6.78e-01 | 1.76e-02 | 1.000000 |
| REACTOME ACTIVATION OF TRKA RECEPTORS | 6 | 6.78e-01 | 9.78e-02 | 1.000000 |
| REACTOME RAF ACTIVATION | 33 | 6.80e-01 | 4.15e-02 | 1.000000 |
| REACTOME SIGNALING BY INTERLEUKINS | 444 | 6.80e-01 | -1.14e-02 | 1.000000 |
| REACTOME ANDROGEN BIOSYNTHESIS | 11 | 6.81e-01 | 7.16e-02 | 1.000000 |
| REACTOME TOLL LIKE RECEPTOR CASCADES | 158 | 6.81e-01 | -1.89e-02 | 1.000000 |
| REACTOME FLT3 SIGNALING THROUGH SRC FAMILY KINASES | 6 | 6.82e-01 | 9.66e-02 | 1.000000 |
| REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | 16 | 6.82e-01 | 5.91e-02 | 1.000000 |
| REACTOME ESTROGEN BIOSYNTHESIS | 6 | 6.83e-01 | -9.64e-02 | 1.000000 |
| REACTOME DEFECTIVE CHSY1 CAUSES TPBS | 7 | 6.84e-01 | 8.88e-02 | 1.000000 |
| REACTOME LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS | 19 | 6.85e-01 | -5.38e-02 | 1.000000 |
| REACTOME REGULATION OF KIT SIGNALING | 16 | 6.85e-01 | 5.86e-02 | 1.000000 |
| REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | 118 | 6.85e-01 | -2.16e-02 | 1.000000 |
| REACTOME DISEASES OF MISMATCH REPAIR MMR | 5 | 6.85e-01 | 1.05e-01 | 1.000000 |
| REACTOME NUCLEOTIDE EXCISION REPAIR | 107 | 6.87e-01 | -2.25e-02 | 1.000000 |
| REACTOME DRUG ADME | 103 | 6.88e-01 | 2.29e-02 | 1.000000 |
| REACTOME ADAPTIVE IMMUNE SYSTEM | 729 | 6.89e-01 | -8.72e-03 | 1.000000 |
| REACTOME DISEASES ASSOCIATED WITH SURFACTANT METABOLISM | 9 | 6.89e-01 | 7.71e-02 | 1.000000 |
| REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS | 6 | 6.89e-01 | -9.43e-02 | 1.000000 |
| REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES | 29 | 6.90e-01 | 4.28e-02 | 1.000000 |
| REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | 11 | 6.90e-01 | -6.94e-02 | 1.000000 |
| REACTOME CD209 DC SIGN SIGNALING | 20 | 6.91e-01 | 5.14e-02 | 1.000000 |
| REACTOME CS DS DEGRADATION | 12 | 6.91e-01 | -6.63e-02 | 1.000000 |
| REACTOME CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION | 24 | 6.91e-01 | -4.69e-02 | 1.000000 |
| REACTOME SIGNALING BY RECEPTOR TYROSINE KINASES | 507 | 6.92e-01 | 1.03e-02 | 1.000000 |
| REACTOME DEUBIQUITINATION | 260 | 6.92e-01 | -1.42e-02 | 1.000000 |
| REACTOME RHO GTPASES ACTIVATE NADPH OXIDASES | 21 | 6.93e-01 | -4.97e-02 | 1.000000 |
| REACTOME ACTIVATION OF RAC1 | 12 | 6.95e-01 | 6.54e-02 | 1.000000 |
| REACTOME SIGNAL AMPLIFICATION | 33 | 6.95e-01 | -3.94e-02 | 1.000000 |
| REACTOME NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10 | 12 | 6.96e-01 | 6.51e-02 | 1.000000 |
| REACTOME SYNTHESIS OF DIPHTHAMIDE EEF2 | 8 | 6.96e-01 | -7.97e-02 | 1.000000 |
| REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1 | 16 | 6.97e-01 | 5.63e-02 | 1.000000 |
| REACTOME SYNTHESIS OF PA | 38 | 6.97e-01 | 3.65e-02 | 1.000000 |
| REACTOME PENTOSE PHOSPHATE PATHWAY | 12 | 6.98e-01 | -6.48e-02 | 1.000000 |
| REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | 15 | 6.98e-01 | -5.79e-02 | 1.000000 |
| REACTOME NICOTINATE METABOLISM | 31 | 6.98e-01 | -4.03e-02 | 1.000000 |
| REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION | 250 | 7.00e-01 | 1.42e-02 | 1.000000 |
| REACTOME CA2 ACTIVATED K CHANNELS | 9 | 7.01e-01 | 7.40e-02 | 1.000000 |
| REACTOME SODIUM PROTON EXCHANGERS | 7 | 7.03e-01 | 8.33e-02 | 1.000000 |
| REACTOME HEDGEHOG OFF STATE | 111 | 7.03e-01 | 2.10e-02 | 1.000000 |
| REACTOME DNA DOUBLE STRAND BREAK RESPONSE | 74 | 7.04e-01 | 2.55e-02 | 1.000000 |
| REACTOME SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION | 8 | 7.04e-01 | -7.75e-02 | 1.000000 |
| REACTOME TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE | 39 | 7.06e-01 | -3.49e-02 | 1.000000 |
| REACTOME GP1B IX V ACTIVATION SIGNALLING | 11 | 7.07e-01 | -6.54e-02 | 1.000000 |
| REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | 9 | 7.08e-01 | -7.22e-02 | 1.000000 |
| REACTOME LAGGING STRAND SYNTHESIS | 19 | 7.09e-01 | -4.94e-02 | 1.000000 |
| REACTOME NUCLEAR EVENTS MEDIATED BY NFE2L2 | 77 | 7.10e-01 | -2.46e-02 | 1.000000 |
| REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS | 5 | 7.10e-01 | 9.61e-02 | 1.000000 |
| REACTOME AQUAPORIN MEDIATED TRANSPORT | 51 | 7.10e-01 | -3.01e-02 | 1.000000 |
| REACTOME SIGNALING BY CSF1 M CSF IN MYELOID CELLS | 30 | 7.11e-01 | 3.92e-02 | 1.000000 |
| REACTOME DEFECTIVE EXT2 CAUSES EXOSTOSES 2 | 12 | 7.11e-01 | 6.17e-02 | 1.000000 |
| REACTOME CELL CELL COMMUNICATION | 126 | 7.11e-01 | 1.91e-02 | 1.000000 |
| REACTOME REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS | 7 | 7.12e-01 | 8.05e-02 | 1.000000 |
| REACTOME DUAL INCISION IN TC NER | 63 | 7.15e-01 | 2.66e-02 | 1.000000 |
| REACTOME SULFIDE OXIDATION TO SULFATE | 6 | 7.16e-01 | -8.57e-02 | 1.000000 |
| REACTOME VEGFR2 MEDIATED CELL PROLIFERATION | 19 | 7.17e-01 | -4.80e-02 | 1.000000 |
| REACTOME HYALURONAN BIOSYNTHESIS AND EXPORT | 5 | 7.18e-01 | 9.31e-02 | 1.000000 |
| REACTOME NADE MODULATES DEATH SIGNALLING | 5 | 7.19e-01 | 9.29e-02 | 1.000000 |
| REACTOME PINK1 PRKN MEDIATED MITOPHAGY | 22 | 7.19e-01 | 4.43e-02 | 1.000000 |
| REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER | 77 | 7.20e-01 | 2.36e-02 | 1.000000 |
| REACTOME SIGNALLING TO P38 VIA RIT AND RIN | 5 | 7.20e-01 | 9.24e-02 | 1.000000 |
| REACTOME DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS | 25 | 7.21e-01 | -4.12e-02 | 1.000000 |
| REACTOME PLATELET SENSITIZATION BY LDL | 17 | 7.21e-01 | 5.00e-02 | 1.000000 |
| REACTOME ER QUALITY CONTROL COMPARTMENT ERQC | 21 | 7.22e-01 | -4.49e-02 | 1.000000 |
| REACTOME CHOLESTEROL BIOSYNTHESIS | 25 | 7.23e-01 | -4.09e-02 | 1.000000 |
| REACTOME FREE FATTY ACIDS REGULATE INSULIN SECRETION | 10 | 7.24e-01 | 6.46e-02 | 1.000000 |
| REACTOME APOPTOSIS | 173 | 7.24e-01 | 1.56e-02 | 1.000000 |
| REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | 28 | 7.24e-01 | -3.85e-02 | 1.000000 |
| REACTOME SARS COV 2 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS | 12 | 7.25e-01 | -5.86e-02 | 1.000000 |
| REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY | 46 | 7.25e-01 | 3.00e-02 | 1.000000 |
| REACTOME EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION | 27 | 7.26e-01 | -3.90e-02 | 1.000000 |
| REACTOME RAC3 GTPASE CYCLE | 85 | 7.26e-01 | 2.20e-02 | 1.000000 |
| REACTOME G2 M DNA REPLICATION CHECKPOINT | 5 | 7.27e-01 | -9.03e-02 | 1.000000 |
| REACTOME TRYPTOPHAN CATABOLISM | 14 | 7.28e-01 | -5.38e-02 | 1.000000 |
| REACTOME GAB1 SIGNALOSOME | 17 | 7.28e-01 | 4.87e-02 | 1.000000 |
| REACTOME ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA | 5 | 7.28e-01 | -8.98e-02 | 1.000000 |
| REACTOME RESOLUTION OF SISTER CHROMATID COHESION | 120 | 7.28e-01 | -1.83e-02 | 1.000000 |
| REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION | 62 | 7.29e-01 | -2.54e-02 | 1.000000 |
| REACTOME ACTIVATION OF BH3 ONLY PROTEINS | 30 | 7.30e-01 | -3.65e-02 | 1.000000 |
| REACTOME TERMINATION OF TRANSLESION DNA SYNTHESIS | 32 | 7.30e-01 | -3.53e-02 | 1.000000 |
| REACTOME TRP CHANNELS | 27 | 7.31e-01 | 3.83e-02 | 1.000000 |
| REACTOME RHOT1 GTPASE CYCLE | 5 | 7.31e-01 | 8.88e-02 | 1.000000 |
| REACTOME IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN | 5 | 7.33e-01 | 8.80e-02 | 1.000000 |
| REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | 13 | 7.33e-01 | 5.45e-02 | 1.000000 |
| REACTOME RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES | 16 | 7.35e-01 | -4.88e-02 | 1.000000 |
| REACTOME NRCAM INTERACTIONS | 6 | 7.35e-01 | 7.96e-02 | 1.000000 |
| REACTOME TNF SIGNALING | 54 | 7.36e-01 | 2.65e-02 | 1.000000 |
| REACTOME NTRK2 ACTIVATES RAC1 | 5 | 7.38e-01 | -8.65e-02 | 1.000000 |
| REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS | 43 | 7.38e-01 | 2.95e-02 | 1.000000 |
| REACTOME FCGR3A MEDIATED IL10 SYNTHESIS | 36 | 7.38e-01 | -3.22e-02 | 1.000000 |
| REACTOME GPER1 SIGNALING | 45 | 7.40e-01 | 2.86e-02 | 1.000000 |
| REACTOME SIGNALING BY PTK6 | 54 | 7.42e-01 | -2.59e-02 | 1.000000 |
| REACTOME BIOSYNTHESIS OF MARESINS | 8 | 7.42e-01 | -6.72e-02 | 1.000000 |
| REACTOME MITOTIC TELOPHASE CYTOKINESIS | 11 | 7.43e-01 | 5.72e-02 | 1.000000 |
| REACTOME PROTON COUPLED MONOCARBOXYLATE TRANSPORT | 6 | 7.43e-01 | -7.74e-02 | 1.000000 |
| REACTOME PROCESSING OF INTRONLESS PRE MRNAS | 19 | 7.43e-01 | -4.34e-02 | 1.000000 |
| REACTOME INTESTINAL ABSORPTION | 5 | 7.43e-01 | -8.45e-02 | 1.000000 |
| REACTOME SIGNALING BY ALK | 26 | 7.44e-01 | -3.70e-02 | 1.000000 |
| REACTOME NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION | 193 | 7.45e-01 | -1.36e-02 | 1.000000 |
| REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS | 35 | 7.45e-01 | -3.18e-02 | 1.000000 |
| REACTOME ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION | 28 | 7.46e-01 | 3.54e-02 | 1.000000 |
| REACTOME CA2 PATHWAY | 62 | 7.46e-01 | 2.38e-02 | 1.000000 |
| REACTOME POST TRANSCRIPTIONAL SILENCING BY SMALL RNAS | 7 | 7.47e-01 | 7.04e-02 | 1.000000 |
| REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | 23 | 7.48e-01 | -3.88e-02 | 1.000000 |
| REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | 23 | 7.49e-01 | 3.86e-02 | 1.000000 |
| REACTOME GABA B RECEPTOR ACTIVATION | 43 | 7.50e-01 | -2.81e-02 | 1.000000 |
| REACTOME DNA REPLICATION INITIATION | 7 | 7.53e-01 | -6.86e-02 | 1.000000 |
| REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA | 28 | 7.54e-01 | -3.42e-02 | 1.000000 |
| REACTOME ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY | 10 | 7.54e-01 | -5.73e-02 | 1.000000 |
| REACTOME CELL CYCLE | 666 | 7.54e-01 | -7.11e-03 | 1.000000 |
| REACTOME PHASE 3 RAPID REPOLARISATION | 8 | 7.54e-01 | -6.39e-02 | 1.000000 |
| REACTOME ALPHA OXIDATION OF PHYTANATE | 6 | 7.55e-01 | 7.36e-02 | 1.000000 |
| REACTOME FANCONI ANEMIA PATHWAY | 35 | 7.55e-01 | -3.04e-02 | 1.000000 |
| REACTOME TRANSCRIPTIONAL REGULATION BY VENTX | 41 | 7.56e-01 | 2.81e-02 | 1.000000 |
| REACTOME KEAP1 NFE2L2 PATHWAY | 104 | 7.56e-01 | -1.76e-02 | 1.000000 |
| REACTOME SIGNALING BY EGFR | 49 | 7.57e-01 | 2.56e-02 | 1.000000 |
| REACTOME LEISHMANIA INFECTION | 156 | 7.57e-01 | 1.44e-02 | 1.000000 |
| REACTOME SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS | 16 | 7.57e-01 | -4.47e-02 | 1.000000 |
| REACTOME TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX | 14 | 7.58e-01 | -4.75e-02 | 1.000000 |
| REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT | 236 | 7.59e-01 | 1.16e-02 | 1.000000 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN | 21 | 7.59e-01 | 3.87e-02 | 1.000000 |
| REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | 12 | 7.59e-01 | 5.12e-02 | 1.000000 |
| REACTOME CROSS PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS PHAGOSOMES | 6 | 7.59e-01 | -7.23e-02 | 1.000000 |
| REACTOME DEFECTIVE CSF2RB CAUSES SMDP5 | 7 | 7.59e-01 | 6.69e-02 | 1.000000 |
| REACTOME IKBA VARIANT LEADS TO EDA ID | 6 | 7.59e-01 | 7.23e-02 | 1.000000 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE | 5 | 7.60e-01 | -7.89e-02 | 1.000000 |
| REACTOME DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS | 14 | 7.61e-01 | -4.70e-02 | 1.000000 |
| REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS | 8 | 7.62e-01 | -6.17e-02 | 1.000000 |
| REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS | 27 | 7.63e-01 | 3.36e-02 | 1.000000 |
| REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX | 19 | 7.63e-01 | 3.99e-02 | 1.000000 |
| REACTOME APOPTOTIC EXECUTION PHASE | 49 | 7.65e-01 | -2.47e-02 | 1.000000 |
| REACTOME GLYCOGEN SYNTHESIS | 13 | 7.66e-01 | -4.76e-02 | 1.000000 |
| REACTOME RELEASE OF HH NP FROM THE SECRETING CELL | 8 | 7.67e-01 | 6.05e-02 | 1.000000 |
| REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | 10 | 7.67e-01 | 5.40e-02 | 1.000000 |
| REACTOME INTERLEUKIN 15 SIGNALING | 13 | 7.67e-01 | -4.74e-02 | 1.000000 |
| REACTOME ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS | 24 | 7.68e-01 | -3.48e-02 | 1.000000 |
| REACTOME METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES | 33 | 7.68e-01 | 2.96e-02 | 1.000000 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS | 9 | 7.68e-01 | -5.67e-02 | 1.000000 |
| REACTOME VASOPRESSIN LIKE RECEPTORS | 5 | 7.69e-01 | 7.58e-02 | 1.000000 |
| REACTOME FGFR1C LIGAND BINDING AND ACTIVATION | 11 | 7.69e-01 | 5.10e-02 | 1.000000 |
| REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | 62 | 7.70e-01 | 2.15e-02 | 1.000000 |
| REACTOME SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER | 15 | 7.70e-01 | 4.36e-02 | 1.000000 |
| REACTOME FGFR2 LIGAND BINDING AND ACTIVATION | 19 | 7.70e-01 | 3.87e-02 | 1.000000 |
| REACTOME TELOMERE EXTENSION BY TELOMERASE | 22 | 7.71e-01 | 3.58e-02 | 1.000000 |
| REACTOME SIGNALING BY NOTCH1 T 7 9 NOTCH1 M1580 K2555 TRANSLOCATION MUTANT | 7 | 7.72e-01 | 6.33e-02 | 1.000000 |
| REACTOME PKA ACTIVATION IN GLUCAGON SIGNALLING | 17 | 7.72e-01 | 4.05e-02 | 1.000000 |
| REACTOME INLA MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS | 9 | 7.72e-01 | -5.57e-02 | 1.000000 |
| REACTOME ABACAVIR ADME | 9 | 7.73e-01 | 5.56e-02 | 1.000000 |
| REACTOME SHC MEDIATED CASCADE FGFR3 | 17 | 7.73e-01 | 4.04e-02 | 1.000000 |
| REACTOME PROGRAMMED CELL DEATH | 204 | 7.73e-01 | -1.17e-02 | 1.000000 |
| REACTOME NONHOMOLOGOUS END JOINING NHEJ | 64 | 7.74e-01 | -2.08e-02 | 1.000000 |
| REACTOME RUNX3 REGULATES P14 ARF | 10 | 7.74e-01 | -5.24e-02 | 1.000000 |
| REACTOME TACHYKININ RECEPTORS BIND TACHYKININS | 5 | 7.74e-01 | 7.40e-02 | 1.000000 |
| REACTOME SYNTHESIS OF PE | 13 | 7.75e-01 | 4.57e-02 | 1.000000 |
| REACTOME CELLULAR RESPONSES TO STIMULI | 779 | 7.76e-01 | 6.00e-03 | 1.000000 |
| REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION | 19 | 7.76e-01 | -3.77e-02 | 1.000000 |
| REACTOME INWARDLY RECTIFYING K CHANNELS | 35 | 7.77e-01 | -2.76e-02 | 1.000000 |
| REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 44 | 7.78e-01 | 2.46e-02 | 1.000000 |
| REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | 30 | 7.79e-01 | -2.97e-02 | 1.000000 |
| REACTOME CARDIAC CONDUCTION | 125 | 7.79e-01 | 1.45e-02 | 1.000000 |
| REACTOME ACTIVATED NTRK3 SIGNALS THROUGH PI3K | 6 | 7.79e-01 | 6.61e-02 | 1.000000 |
| REACTOME SARS COV INFECTIONS | 392 | 7.80e-01 | 8.23e-03 | 1.000000 |
| REACTOME SODIUM CALCIUM EXCHANGERS | 11 | 7.80e-01 | -4.86e-02 | 1.000000 |
| REACTOME ASPARTATE AND ASPARAGINE METABOLISM | 11 | 7.83e-01 | -4.79e-02 | 1.000000 |
| REACTOME CD163 MEDIATING AN ANTI INFLAMMATORY RESPONSE | 9 | 7.84e-01 | -5.29e-02 | 1.000000 |
| REACTOME ACTIVATION OF CASPASES THROUGH APOPTOSOME MEDIATED CLEAVAGE | 5 | 7.85e-01 | -7.04e-02 | 1.000000 |
| REACTOME LDL REMODELING | 6 | 7.85e-01 | 6.42e-02 | 1.000000 |
| REACTOME REGULATION OF NF KAPPA B SIGNALING | 17 | 7.86e-01 | 3.81e-02 | 1.000000 |
| REACTOME TRIGLYCERIDE CATABOLISM | 23 | 7.86e-01 | -3.27e-02 | 1.000000 |
| REACTOME SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE | 91 | 7.86e-01 | 1.65e-02 | 1.000000 |
| REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | 20 | 7.86e-01 | -3.50e-02 | 1.000000 |
| REACTOME MITOTIC PROPHASE | 134 | 7.86e-01 | 1.36e-02 | 1.000000 |
| REACTOME TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS | 29 | 7.87e-01 | -2.89e-02 | 1.000000 |
| REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS | 5 | 7.88e-01 | 6.94e-02 | 1.000000 |
| REACTOME DIGESTION | 17 | 7.89e-01 | 3.76e-02 | 1.000000 |
| REACTOME RORA ACTIVATES GENE EXPRESSION | 17 | 7.89e-01 | -3.75e-02 | 1.000000 |
| REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | 263 | 7.90e-01 | 9.56e-03 | 1.000000 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST | 14 | 7.90e-01 | -4.11e-02 | 1.000000 |
| REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | 73 | 7.91e-01 | 1.79e-02 | 1.000000 |
| REACTOME COMPLEX I BIOGENESIS | 49 | 7.93e-01 | 2.17e-02 | 1.000000 |
| REACTOME PROTEIN REPAIR | 6 | 7.94e-01 | -6.17e-02 | 1.000000 |
| REACTOME P2Y RECEPTORS | 9 | 7.94e-01 | -5.02e-02 | 1.000000 |
| REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | 15 | 7.94e-01 | -3.89e-02 | 1.000000 |
| REACTOME SEMA4D IN SEMAPHORIN SIGNALING | 24 | 7.95e-01 | -3.06e-02 | 1.000000 |
| REACTOME DISEASES OF BASE EXCISION REPAIR | 5 | 7.95e-01 | -6.70e-02 | 1.000000 |
| REACTOME SIGNALING BY WNT IN CANCER | 32 | 7.95e-01 | 2.65e-02 | 1.000000 |
| REACTOME INTERLEUKIN 27 SIGNALING | 11 | 7.96e-01 | 4.51e-02 | 1.000000 |
| REACTOME DISEASES OF METABOLISM | 237 | 7.96e-01 | 9.75e-03 | 1.000000 |
| REACTOME SARS COV 1 HOST INTERACTIONS | 92 | 7.97e-01 | -1.55e-02 | 1.000000 |
| REACTOME SIALIC ACID METABOLISM | 33 | 7.98e-01 | -2.57e-02 | 1.000000 |
| REACTOME DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B | 7 | 7.99e-01 | -5.57e-02 | 1.000000 |
| REACTOME PROTEIN LOCALIZATION | 153 | 7.99e-01 | -1.19e-02 | 1.000000 |
| REACTOME BASIGIN INTERACTIONS | 24 | 7.99e-01 | -3.00e-02 | 1.000000 |
| REACTOME NEPHRIN FAMILY INTERACTIONS | 22 | 7.99e-01 | 3.13e-02 | 1.000000 |
| REACTOME G2 PHASE | 5 | 7.99e-01 | -6.57e-02 | 1.000000 |
| REACTOME NR1H2 AND NR1H3 MEDIATED SIGNALING | 46 | 7.99e-01 | 2.16e-02 | 1.000000 |
| REACTOME ADRENOCEPTORS | 9 | 8.00e-01 | 4.89e-02 | 1.000000 |
| REACTOME REGULATION OF PTEN GENE TRANSCRIPTION | 59 | 8.01e-01 | 1.90e-02 | 1.000000 |
| REACTOME SUMOYLATION OF RNA BINDING PROTEINS | 47 | 8.01e-01 | 2.12e-02 | 1.000000 |
| REACTOME THYROXINE BIOSYNTHESIS | 10 | 8.02e-01 | 4.58e-02 | 1.000000 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FYN | 7 | 8.02e-01 | -5.48e-02 | 1.000000 |
| REACTOME HDL CLEARANCE | 5 | 8.03e-01 | 6.44e-02 | 1.000000 |
| REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING | 25 | 8.04e-01 | 2.86e-02 | 1.000000 |
| REACTOME RHOA GTPASE CYCLE | 142 | 8.05e-01 | 1.20e-02 | 1.000000 |
| REACTOME ACTIVATION OF RAS IN B CELLS | 5 | 8.06e-01 | 6.36e-02 | 1.000000 |
| REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | 15 | 8.06e-01 | 3.66e-02 | 1.000000 |
| REACTOME PEPTIDE HORMONE BIOSYNTHESIS | 13 | 8.07e-01 | -3.91e-02 | 1.000000 |
| REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | 51 | 8.08e-01 | 1.97e-02 | 1.000000 |
| REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | 111 | 8.08e-01 | 1.33e-02 | 1.000000 |
| REACTOME SARS COV 2 HOST INTERACTIONS | 191 | 8.10e-01 | 1.01e-02 | 1.000000 |
| REACTOME DNA STRAND ELONGATION | 31 | 8.11e-01 | 2.49e-02 | 1.000000 |
| REACTOME SEROTONIN RECEPTORS | 11 | 8.11e-01 | 4.16e-02 | 1.000000 |
| REACTOME TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS | 36 | 8.12e-01 | 2.30e-02 | 1.000000 |
| REACTOME RHO GTPASES ACTIVATE PAKS | 19 | 8.12e-01 | -3.15e-02 | 1.000000 |
| REACTOME RIP MEDIATED NFKB ACTIVATION VIA ZBP1 | 16 | 8.12e-01 | 3.43e-02 | 1.000000 |
| REACTOME TRANSCRIPTIONAL REGULATION BY RUNX2 | 117 | 8.13e-01 | -1.27e-02 | 1.000000 |
| REACTOME RAB REGULATION OF TRAFFICKING | 110 | 8.14e-01 | 1.30e-02 | 1.000000 |
| REACTOME EGFR TRANSACTIVATION BY GASTRIN | 9 | 8.14e-01 | 4.52e-02 | 1.000000 |
| REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | 63 | 8.15e-01 | 1.71e-02 | 1.000000 |
| REACTOME BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA | 5 | 8.15e-01 | -6.05e-02 | 1.000000 |
| REACTOME REGULATION OF RUNX1 EXPRESSION AND ACTIVITY | 17 | 8.15e-01 | 3.28e-02 | 1.000000 |
| REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | 101 | 8.16e-01 | -1.34e-02 | 1.000000 |
| REACTOME SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS | 14 | 8.16e-01 | 3.60e-02 | 1.000000 |
| REACTOME HCMV EARLY EVENTS | 128 | 8.16e-01 | -1.19e-02 | 1.000000 |
| REACTOME LTC4 CYSLTR MEDIATED IL4 PRODUCTION | 6 | 8.16e-01 | 5.49e-02 | 1.000000 |
| REACTOME ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM | 12 | 8.16e-01 | -3.87e-02 | 1.000000 |
| REACTOME SIGNALING BY EGFR IN CANCER | 25 | 8.17e-01 | -2.68e-02 | 1.000000 |
| REACTOME PREDNISONE ADME | 10 | 8.17e-01 | -4.22e-02 | 1.000000 |
| REACTOME HCMV LATE EVENTS | 110 | 8.18e-01 | 1.27e-02 | 1.000000 |
| REACTOME SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA PHE | 6 | 8.19e-01 | -5.41e-02 | 1.000000 |
| REACTOME CROSSLINKING OF COLLAGEN FIBRILS | 16 | 8.20e-01 | -3.28e-02 | 1.000000 |
| REACTOME INTERLEUKIN 6 FAMILY SIGNALING | 24 | 8.22e-01 | 2.65e-02 | 1.000000 |
| REACTOME TRANSPORT OF RCBL WITHIN THE BODY | 8 | 8.22e-01 | -4.58e-02 | 1.000000 |
| REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | 122 | 8.23e-01 | 1.17e-02 | 1.000000 |
| REACTOME DAP12 INTERACTIONS | 37 | 8.23e-01 | 2.12e-02 | 1.000000 |
| REACTOME MYOCLONIC EPILEPSY OF LAFORA | 9 | 8.23e-01 | -4.30e-02 | 1.000000 |
| REACTOME SARS COV 2 ACTIVATES MODULATES INNATE AND ADAPTIVE IMMUNE RESPONSES | 118 | 8.24e-01 | 1.19e-02 | 1.000000 |
| REACTOME SNRNP ASSEMBLY | 53 | 8.24e-01 | 1.77e-02 | 1.000000 |
| REACTOME NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY | 6 | 8.24e-01 | 5.25e-02 | 1.000000 |
| REACTOME GLYCOSPHINGOLIPID METABOLISM | 39 | 8.25e-01 | -2.04e-02 | 1.000000 |
| REACTOME ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING | 9 | 8.25e-01 | 4.24e-02 | 1.000000 |
| REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | 23 | 8.26e-01 | -2.65e-02 | 1.000000 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH PI3K | 7 | 8.27e-01 | 4.78e-02 | 1.000000 |
| REACTOME RHOD GTPASE CYCLE | 49 | 8.27e-01 | -1.80e-02 | 1.000000 |
| REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS | 42 | 8.31e-01 | 1.91e-02 | 1.000000 |
| REACTOME FCERI MEDIATED CA 2 MOBILIZATION | 30 | 8.31e-01 | 2.25e-02 | 1.000000 |
| REACTOME G1 S DNA DAMAGE CHECKPOINTS | 67 | 8.31e-01 | 1.51e-02 | 1.000000 |
| REACTOME ARACHIDONATE PRODUCTION FROM DAG | 5 | 8.31e-01 | -5.50e-02 | 1.000000 |
| REACTOME REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION | 9 | 8.32e-01 | 4.08e-02 | 1.000000 |
| REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | 27 | 8.33e-01 | -2.35e-02 | 1.000000 |
| REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS | 15 | 8.33e-01 | 3.15e-02 | 1.000000 |
| REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION | 29 | 8.33e-01 | -2.26e-02 | 1.000000 |
| REACTOME DEFECTIVE RIPK1 MEDIATED REGULATED NECROSIS | 7 | 8.33e-01 | 4.59e-02 | 1.000000 |
| REACTOME GLUCURONIDATION | 23 | 8.34e-01 | 2.53e-02 | 1.000000 |
| REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3 | 679 | 8.35e-01 | 4.69e-03 | 1.000000 |
| REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | 134 | 8.35e-01 | 1.04e-02 | 1.000000 |
| REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | 16 | 8.35e-01 | -3.00e-02 | 1.000000 |
| REACTOME HDL REMODELING | 10 | 8.37e-01 | 3.75e-02 | 1.000000 |
| REACTOME GLYCOLYSIS | 70 | 8.38e-01 | -1.42e-02 | 1.000000 |
| REACTOME TRIF MEDIATED PROGRAMMED CELL DEATH | 9 | 8.38e-01 | -3.94e-02 | 1.000000 |
| REACTOME SYNTHESIS OF PC | 27 | 8.38e-01 | 2.27e-02 | 1.000000 |
| REACTOME G BETA GAMMA SIGNALLING THROUGH CDC42 | 19 | 8.39e-01 | -2.69e-02 | 1.000000 |
| REACTOME ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA | 15 | 8.39e-01 | -3.03e-02 | 1.000000 |
| REACTOME PHYSIOLOGICAL FACTORS | 14 | 8.40e-01 | -3.12e-02 | 1.000000 |
| REACTOME FGFR2C LIGAND BINDING AND ACTIVATION | 12 | 8.41e-01 | 3.35e-02 | 1.000000 |
| REACTOME REGULATION OF PTEN STABILITY AND ACTIVITY | 67 | 8.41e-01 | 1.42e-02 | 1.000000 |
| REACTOME NUCLEAR PORE COMPLEX NPC DISASSEMBLY | 36 | 8.41e-01 | -1.93e-02 | 1.000000 |
| REACTOME DOWNREGULATION OF ERBB4 SIGNALING | 9 | 8.43e-01 | 3.81e-02 | 1.000000 |
| REACTOME FATTY ACIDS BOUND TO GPR40 FFAR1 REGULATE INSULIN SECRETION | 8 | 8.44e-01 | 4.02e-02 | 1.000000 |
| REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION | 42 | 8.45e-01 | 1.74e-02 | 1.000000 |
| REACTOME SELENOAMINO ACID METABOLISM | 108 | 8.46e-01 | 1.08e-02 | 1.000000 |
| REACTOME LDL CLEARANCE | 19 | 8.46e-01 | -2.57e-02 | 1.000000 |
| REACTOME BASE EXCISION REPAIR | 87 | 8.46e-01 | -1.20e-02 | 1.000000 |
| REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | 14 | 8.47e-01 | 2.98e-02 | 1.000000 |
| REACTOME TRANSLESION SYNTHESIS BY POLH | 19 | 8.48e-01 | -2.54e-02 | 1.000000 |
| REACTOME INTERLEUKIN 10 SIGNALING | 43 | 8.48e-01 | 1.69e-02 | 1.000000 |
| REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | 11 | 8.48e-01 | 3.33e-02 | 1.000000 |
| REACTOME DEADENYLATION OF MRNA | 25 | 8.49e-01 | 2.20e-02 | 1.000000 |
| REACTOME GLYCEROPHOSPHOLIPID CATABOLISM | 7 | 8.49e-01 | -4.14e-02 | 1.000000 |
| REACTOME ATTACHMENT OF GPI ANCHOR TO UPAR | 7 | 8.50e-01 | -4.14e-02 | 1.000000 |
| REACTOME RRNA MODIFICATION IN THE MITOCHONDRION | 6 | 8.50e-01 | -4.46e-02 | 1.000000 |
| REACTOME CYTOCHROME C MEDIATED APOPTOTIC RESPONSE | 12 | 8.51e-01 | 3.12e-02 | 1.000000 |
| REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX | 91 | 8.51e-01 | 1.14e-02 | 1.000000 |
| REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | 91 | 8.52e-01 | 1.13e-02 | 1.000000 |
| REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL | 41 | 8.52e-01 | -1.68e-02 | 1.000000 |
| REACTOME RETINOID CYCLE DISEASE EVENTS | 11 | 8.52e-01 | 3.25e-02 | 1.000000 |
| REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE | 11 | 8.53e-01 | -3.22e-02 | 1.000000 |
| REACTOME ENOS ACTIVATION | 11 | 8.54e-01 | 3.21e-02 | 1.000000 |
| REACTOME TRANSLESION SYNTHESIS BY POLK | 17 | 8.54e-01 | -2.58e-02 | 1.000000 |
| REACTOME OPSINS | 7 | 8.57e-01 | 3.92e-02 | 1.000000 |
| REACTOME SIGNALING BY RETINOIC ACID | 41 | 8.58e-01 | -1.61e-02 | 1.000000 |
| REACTOME RNA POLYMERASE III TRANSCRIPTION | 41 | 8.60e-01 | 1.59e-02 | 1.000000 |
| REACTOME RHOG GTPASE CYCLE | 71 | 8.61e-01 | 1.20e-02 | 1.000000 |
| REACTOME SIGNALING BY HEDGEHOG | 148 | 8.61e-01 | -8.32e-03 | 1.000000 |
| REACTOME NGF INDEPENDANT TRKA ACTIVATION | 5 | 8.62e-01 | 4.48e-02 | 1.000000 |
| REACTOME RUNX3 REGULATES NOTCH SIGNALING | 13 | 8.63e-01 | -2.77e-02 | 1.000000 |
| REACTOME TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT | 18 | 8.63e-01 | 2.35e-02 | 1.000000 |
| REACTOME G PROTEIN ACTIVATION | 24 | 8.63e-01 | 2.03e-02 | 1.000000 |
| REACTOME HIV LIFE CYCLE | 145 | 8.63e-01 | 8.27e-03 | 1.000000 |
| REACTOME RHO GTPASE CYCLE | 423 | 8.64e-01 | 4.84e-03 | 1.000000 |
| REACTOME INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION | 21 | 8.65e-01 | 2.14e-02 | 1.000000 |
| REACTOME CALCINEURIN ACTIVATES NFAT | 9 | 8.66e-01 | -3.24e-02 | 1.000000 |
| REACTOME PRE NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM | 6 | 8.67e-01 | -3.96e-02 | 1.000000 |
| REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES | 10 | 8.67e-01 | 3.05e-02 | 1.000000 |
| REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION | 32 | 8.68e-01 | 1.70e-02 | 1.000000 |
| REACTOME TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS | 55 | 8.68e-01 | -1.30e-02 | 1.000000 |
| REACTOME TRANSPORT OF NUCLEOTIDE SUGARS | 8 | 8.68e-01 | -3.38e-02 | 1.000000 |
| REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF | 17 | 8.69e-01 | 2.31e-02 | 1.000000 |
| REACTOME FGFR3 LIGAND BINDING AND ACTIVATION | 12 | 8.69e-01 | -2.74e-02 | 1.000000 |
| REACTOME RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS | 9 | 8.69e-01 | 3.17e-02 | 1.000000 |
| REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM | 688 | 8.70e-01 | 3.66e-03 | 1.000000 |
| REACTOME HS GAG DEGRADATION | 19 | 8.70e-01 | -2.16e-02 | 1.000000 |
| REACTOME PKMTS METHYLATE HISTONE LYSINES | 64 | 8.71e-01 | 1.18e-02 | 1.000000 |
| REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE | 11 | 8.71e-01 | 2.83e-02 | 1.000000 |
| REACTOME SHC RELATED EVENTS TRIGGERED BY IGF1R | 9 | 8.72e-01 | -3.10e-02 | 1.000000 |
| REACTOME SIGNALING BY LEPTIN | 11 | 8.72e-01 | -2.80e-02 | 1.000000 |
| REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES | 14 | 8.75e-01 | -2.42e-02 | 1.000000 |
| REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING | 30 | 8.76e-01 | 1.64e-02 | 1.000000 |
| REACTOME DEFECTS IN COBALAMIN B12 METABOLISM | 13 | 8.77e-01 | -2.49e-02 | 1.000000 |
| REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS | 5 | 8.77e-01 | -4.00e-02 | 1.000000 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING | 5 | 8.78e-01 | -3.97e-02 | 1.000000 |
| REACTOME CDC42 GTPASE CYCLE | 144 | 8.78e-01 | 7.43e-03 | 1.000000 |
| REACTOME PYRUVATE METABOLISM | 29 | 8.78e-01 | 1.65e-02 | 1.000000 |
| REACTOME ORGANIC ANION TRANSPORTERS | 10 | 8.78e-01 | 2.80e-02 | 1.000000 |
| REACTOME MET ACTIVATES RAP1 AND RAC1 | 11 | 8.79e-01 | 2.66e-02 | 1.000000 |
| REACTOME RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR | 19 | 8.79e-01 | -2.01e-02 | 1.000000 |
| REACTOME RET SIGNALING | 40 | 8.79e-01 | -1.39e-02 | 1.000000 |
| REACTOME TRANSPORT AND SYNTHESIS OF PAPS | 6 | 8.80e-01 | 3.56e-02 | 1.000000 |
| REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR | 24 | 8.80e-01 | -1.78e-02 | 1.000000 |
| REACTOME GAP JUNCTION ASSEMBLY | 36 | 8.81e-01 | 1.44e-02 | 1.000000 |
| REACTOME NEF MEDIATED CD4 DOWN REGULATION | 9 | 8.82e-01 | -2.87e-02 | 1.000000 |
| REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS | 6 | 8.83e-01 | -3.47e-02 | 1.000000 |
| REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY | 72 | 8.83e-01 | -1.00e-02 | 1.000000 |
| REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | 11 | 8.83e-01 | 2.55e-02 | 1.000000 |
| REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | 22 | 8.84e-01 | 1.80e-02 | 1.000000 |
| REACTOME MITOCHONDRIAL UNCOUPLING | 5 | 8.85e-01 | 3.75e-02 | 1.000000 |
| REACTOME NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 11 | 8.85e-01 | 2.51e-02 | 1.000000 |
| REACTOME CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE | 49 | 8.86e-01 | -1.19e-02 | 1.000000 |
| REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | 13 | 8.86e-01 | 2.30e-02 | 1.000000 |
| REACTOME P38MAPK EVENTS | 13 | 8.86e-01 | 2.30e-02 | 1.000000 |
| REACTOME PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING | 11 | 8.86e-01 | 2.49e-02 | 1.000000 |
| REACTOME CONSTITUTIVE SIGNALING BY EGFRVIII | 15 | 8.86e-01 | -2.13e-02 | 1.000000 |
| REACTOME PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING | 5 | 8.87e-01 | 3.65e-02 | 1.000000 |
| REACTOME BETA CATENIN PHOSPHORYLATION CASCADE | 16 | 8.88e-01 | -2.04e-02 | 1.000000 |
| REACTOME INTERLEUKIN 2 FAMILY SIGNALING | 40 | 8.88e-01 | 1.29e-02 | 1.000000 |
| REACTOME NEDDYLATION | 235 | 8.88e-01 | 5.34e-03 | 1.000000 |
| REACTOME EGFR DOWNREGULATION | 30 | 8.88e-01 | -1.49e-02 | 1.000000 |
| REACTOME MISMATCH REPAIR | 15 | 8.88e-01 | -2.10e-02 | 1.000000 |
| REACTOME PLATELET CALCIUM HOMEOSTASIS | 27 | 8.89e-01 | 1.56e-02 | 1.000000 |
| REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | 20 | 8.91e-01 | 1.78e-02 | 1.000000 |
| REACTOME DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A | 5 | 8.91e-01 | 3.53e-02 | 1.000000 |
| REACTOME SIGNALING BY SCF KIT | 42 | 8.92e-01 | 1.21e-02 | 1.000000 |
| REACTOME SMALL INTERFERING RNA SIRNA BIOGENESIS | 9 | 8.92e-01 | -2.62e-02 | 1.000000 |
| REACTOME SEMAPHORIN INTERACTIONS | 61 | 8.92e-01 | -1.00e-02 | 1.000000 |
| REACTOME ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS | 20 | 8.93e-01 | 1.73e-02 | 1.000000 |
| REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX | 39 | 8.93e-01 | -1.24e-02 | 1.000000 |
| REACTOME HYDROLYSIS OF LPC | 9 | 8.94e-01 | -2.56e-02 | 1.000000 |
| REACTOME NUCLEAR ENVELOPE BREAKDOWN | 52 | 8.95e-01 | -1.06e-02 | 1.000000 |
| REACTOME APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS | 87 | 8.95e-01 | 8.17e-03 | 1.000000 |
| REACTOME ETHANOL OXIDATION | 12 | 8.95e-01 | 2.19e-02 | 1.000000 |
| REACTOME SYNTHESIS OF DNA | 119 | 8.96e-01 | 6.94e-03 | 1.000000 |
| REACTOME MOLYBDENUM COFACTOR BIOSYNTHESIS | 6 | 8.96e-01 | 3.08e-02 | 1.000000 |
| REACTOME PTK6 PROMOTES HIF1A STABILIZATION | 6 | 8.97e-01 | 3.06e-02 | 1.000000 |
| REACTOME ACTIVATED NTRK3 SIGNALS THROUGH RAS | 8 | 8.97e-01 | -2.64e-02 | 1.000000 |
| REACTOME CELL CYCLE MITOTIC | 539 | 8.98e-01 | -3.24e-03 | 1.000000 |
| REACTOME RNA POLYMERASE III TRANSCRIPTION TERMINATION | 23 | 8.98e-01 | -1.55e-02 | 1.000000 |
| REACTOME RNA POLYMERASE III CHAIN ELONGATION | 18 | 8.98e-01 | 1.74e-02 | 1.000000 |
| REACTOME RHOH GTPASE CYCLE | 37 | 8.99e-01 | -1.21e-02 | 1.000000 |
| REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER | 49 | 8.99e-01 | 1.05e-02 | 1.000000 |
| REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION | 26 | 9.00e-01 | 1.42e-02 | 1.000000 |
| REACTOME SIGNALING BY ERBB2 ECD MUTANTS | 16 | 9.01e-01 | -1.80e-02 | 1.000000 |
| REACTOME DARPP 32 EVENTS | 24 | 9.01e-01 | -1.46e-02 | 1.000000 |
| REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | 21 | 9.02e-01 | 1.55e-02 | 1.000000 |
| REACTOME RA BIOSYNTHESIS PATHWAY | 22 | 9.04e-01 | 1.48e-02 | 1.000000 |
| REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | 31 | 9.05e-01 | 1.24e-02 | 1.000000 |
| REACTOME BETA OXIDATION OF BUTANOYL COA TO ACETYL COA | 5 | 9.05e-01 | -3.09e-02 | 1.000000 |
| REACTOME NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 25 | 9.05e-01 | 1.38e-02 | 1.000000 |
| REACTOME RUNX2 REGULATES BONE DEVELOPMENT | 29 | 9.05e-01 | 1.28e-02 | 1.000000 |
| REACTOME SIGNALING BY MST1 | 5 | 9.05e-01 | 3.07e-02 | 1.000000 |
| REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS | 14 | 9.05e-01 | 1.84e-02 | 1.000000 |
| REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN | 32 | 9.07e-01 | 1.20e-02 | 1.000000 |
| REACTOME CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND | 9 | 9.07e-01 | 2.25e-02 | 1.000000 |
| REACTOME GDP FUCOSE BIOSYNTHESIS | 6 | 9.07e-01 | -2.75e-02 | 1.000000 |
| REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS | 33 | 9.08e-01 | 1.17e-02 | 1.000000 |
| REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | 11 | 9.08e-01 | -2.02e-02 | 1.000000 |
| REACTOME MET ACTIVATES RAS SIGNALING | 11 | 9.09e-01 | -2.00e-02 | 1.000000 |
| REACTOME ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS | 7 | 9.09e-01 | 2.49e-02 | 1.000000 |
| REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | 10 | 9.09e-01 | 2.08e-02 | 1.000000 |
| REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS | 20 | 9.10e-01 | -1.46e-02 | 1.000000 |
| REACTOME ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS | 20 | 9.10e-01 | -1.45e-02 | 1.000000 |
| REACTOME LOSS OF FUNCTION OF SMAD2 3 IN CANCER | 7 | 9.10e-01 | 2.46e-02 | 1.000000 |
| REACTOME NUCLEOTIDE SALVAGE | 21 | 9.11e-01 | 1.42e-02 | 1.000000 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH RAS | 9 | 9.11e-01 | 2.16e-02 | 1.000000 |
| REACTOME SEPARATION OF SISTER CHROMATIDS | 184 | 9.11e-01 | 4.76e-03 | 1.000000 |
| REACTOME DERMATAN SULFATE BIOSYNTHESIS | 10 | 9.12e-01 | 2.03e-02 | 1.000000 |
| REACTOME SENSING OF DNA DOUBLE STRAND BREAKS | 6 | 9.12e-01 | -2.61e-02 | 1.000000 |
| REACTOME NONCANONICAL ACTIVATION OF NOTCH3 | 8 | 9.13e-01 | 2.23e-02 | 1.000000 |
| REACTOME PHASE 2 PLATEAU PHASE | 14 | 9.14e-01 | 1.67e-02 | 1.000000 |
| REACTOME SULFUR AMINO ACID METABOLISM | 27 | 9.15e-01 | -1.18e-02 | 1.000000 |
| REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS | 46 | 9.16e-01 | 9.03e-03 | 1.000000 |
| REACTOME LATE SARS COV 2 INFECTION EVENTS | 67 | 9.16e-01 | 7.45e-03 | 1.000000 |
| REACTOME APEX1 INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | 7 | 9.17e-01 | 2.27e-02 | 1.000000 |
| REACTOME CA DEPENDENT EVENTS | 36 | 9.17e-01 | -9.98e-03 | 1.000000 |
| REACTOME TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER | 76 | 9.18e-01 | -6.84e-03 | 1.000000 |
| REACTOME LIPID PARTICLE ORGANIZATION | 6 | 9.18e-01 | -2.43e-02 | 1.000000 |
| REACTOME SIGNALING BY LRP5 MUTANTS | 6 | 9.21e-01 | 2.33e-02 | 1.000000 |
| REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | 54 | 9.21e-01 | 7.76e-03 | 1.000000 |
| REACTOME TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS | 26 | 9.22e-01 | 1.11e-02 | 1.000000 |
| REACTOME CLEC7A DECTIN 1 SIGNALING | 97 | 9.22e-01 | -5.77e-03 | 1.000000 |
| REACTOME REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO | 10 | 9.22e-01 | -1.79e-02 | 1.000000 |
| REACTOME SHC MEDIATED CASCADE FGFR1 | 21 | 9.22e-01 | 1.23e-02 | 1.000000 |
| REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | 13 | 9.25e-01 | 1.52e-02 | 1.000000 |
| REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | 18 | 9.26e-01 | -1.27e-02 | 1.000000 |
| REACTOME INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS | 37 | 9.26e-01 | -8.88e-03 | 1.000000 |
| REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | 19 | 9.26e-01 | -1.23e-02 | 1.000000 |
| REACTOME FRUCTOSE CATABOLISM | 5 | 9.27e-01 | 2.35e-02 | 1.000000 |
| REACTOME HISTIDINE CATABOLISM | 8 | 9.28e-01 | 1.85e-02 | 1.000000 |
| REACTOME DEPOLYMERISATION OF THE NUCLEAR LAMINA | 14 | 9.30e-01 | -1.36e-02 | 1.000000 |
| REACTOME REGULATION OF BACH1 ACTIVITY | 11 | 9.30e-01 | 1.53e-02 | 1.000000 |
| REACTOME SARS COV 2 INFECTION | 281 | 9.30e-01 | 3.02e-03 | 1.000000 |
| REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS | 13 | 9.32e-01 | -1.37e-02 | 1.000000 |
| REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | 24 | 9.33e-01 | -9.98e-03 | 1.000000 |
| REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B | 24 | 9.33e-01 | -9.91e-03 | 1.000000 |
| REACTOME OTHER INTERLEUKIN SIGNALING | 24 | 9.34e-01 | 9.81e-03 | 1.000000 |
| REACTOME REGULATION OF MECP2 EXPRESSION AND ACTIVITY | 30 | 9.34e-01 | 8.76e-03 | 1.000000 |
| REACTOME MODULATION BY MTB OF HOST IMMUNE SYSTEM | 6 | 9.34e-01 | 1.94e-02 | 1.000000 |
| REACTOME CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY | 12 | 9.35e-01 | 1.36e-02 | 1.000000 |
| REACTOME DIGESTION AND ABSORPTION | 22 | 9.37e-01 | 9.80e-03 | 1.000000 |
| REACTOME DRUG MEDIATED INHIBITION OF CDK4 CDK6 ACTIVITY | 5 | 9.38e-01 | -2.02e-02 | 1.000000 |
| REACTOME TNFR2 NON CANONICAL NF KB PATHWAY | 96 | 9.38e-01 | 4.62e-03 | 1.000000 |
| REACTOME POLB DEPENDENT LONG PATCH BASE EXCISION REPAIR | 8 | 9.38e-01 | -1.59e-02 | 1.000000 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS | 9 | 9.38e-01 | -1.49e-02 | 1.000000 |
| REACTOME FATTY ACIDS | 15 | 9.38e-01 | -1.15e-02 | 1.000000 |
| REACTOME APOPTOTIC FACTOR MEDIATED RESPONSE | 19 | 9.41e-01 | 9.86e-03 | 1.000000 |
| REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | 36 | 9.41e-01 | 7.09e-03 | 1.000000 |
| REACTOME ERKS ARE INACTIVATED | 13 | 9.44e-01 | 1.13e-02 | 1.000000 |
| REACTOME MITOTIC METAPHASE AND ANAPHASE | 228 | 9.46e-01 | -2.58e-03 | 1.000000 |
| REACTOME HEME DEGRADATION | 15 | 9.47e-01 | 9.99e-03 | 1.000000 |
| REACTOME RUNX2 REGULATES CHONDROCYTE MATURATION | 5 | 9.47e-01 | -1.71e-02 | 1.000000 |
| REACTOME ION TRANSPORT BY P TYPE ATPASES | 51 | 9.48e-01 | -5.29e-03 | 1.000000 |
| REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION | 90 | 9.49e-01 | -3.94e-03 | 1.000000 |
| REACTOME SMOOTH MUSCLE CONTRACTION | 43 | 9.49e-01 | -5.63e-03 | 1.000000 |
| REACTOME RHO GTPASES ACTIVATE FORMINS | 136 | 9.50e-01 | 3.13e-03 | 1.000000 |
| REACTOME PROLACTIN RECEPTOR SIGNALING | 15 | 9.50e-01 | -9.32e-03 | 1.000000 |
| REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | 16 | 9.50e-01 | 8.98e-03 | 1.000000 |
| REACTOME OTHER SEMAPHORIN INTERACTIONS | 18 | 9.51e-01 | 8.44e-03 | 1.000000 |
| REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | 26 | 9.51e-01 | -6.99e-03 | 1.000000 |
| REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1 | 25 | 9.51e-01 | -7.06e-03 | 1.000000 |
| REACTOME THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT | 77 | 9.52e-01 | -3.97e-03 | 1.000000 |
| REACTOME PRE NOTCH PROCESSING IN GOLGI | 18 | 9.53e-01 | 8.08e-03 | 1.000000 |
| REACTOME DEGRADATION OF CYSTEINE AND HOMOCYSTEINE | 15 | 9.53e-01 | -8.76e-03 | 1.000000 |
| REACTOME RHOU GTPASE CYCLE | 37 | 9.55e-01 | 5.42e-03 | 1.000000 |
| REACTOME INTERLEUKIN 21 SIGNALING | 9 | 9.55e-01 | -1.10e-02 | 1.000000 |
| REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA | 11 | 9.55e-01 | 9.80e-03 | 1.000000 |
| REACTOME INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL | 14 | 9.56e-01 | -8.59e-03 | 1.000000 |
| REACTOME TYROSINE CATABOLISM | 5 | 9.56e-01 | 1.41e-02 | 1.000000 |
| REACTOME RESPIRATORY ELECTRON TRANSPORT | 90 | 9.56e-01 | -3.33e-03 | 1.000000 |
| REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM | 78 | 9.58e-01 | 3.45e-03 | 1.000000 |
| REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK | 17 | 9.59e-01 | 7.13e-03 | 1.000000 |
| REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY | 14 | 9.60e-01 | -7.81e-03 | 1.000000 |
| REACTOME TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA | 36 | 9.61e-01 | 4.74e-03 | 1.000000 |
| REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND | 14 | 9.62e-01 | -7.39e-03 | 1.000000 |
| REACTOME PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS | 21 | 9.62e-01 | 6.00e-03 | 1.000000 |
| REACTOME EPHA MEDIATED GROWTH CONE COLLAPSE | 29 | 9.63e-01 | 4.97e-03 | 1.000000 |
| REACTOME PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS | 7 | 9.64e-01 | -9.97e-03 | 1.000000 |
| REACTOME CGMP EFFECTS | 16 | 9.65e-01 | -6.42e-03 | 1.000000 |
| REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS | 66 | 9.65e-01 | -3.13e-03 | 1.000000 |
| REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | 15 | 9.65e-01 | 6.55e-03 | 1.000000 |
| REACTOME MIRO GTPASE CYCLE | 8 | 9.66e-01 | -8.74e-03 | 1.000000 |
| REACTOME LONG TERM POTENTIATION | 22 | 9.66e-01 | 5.22e-03 | 1.000000 |
| REACTOME SIGNALING BY PDGFR IN DISEASE | 20 | 9.66e-01 | -5.46e-03 | 1.000000 |
| REACTOME ION HOMEOSTASIS | 52 | 9.67e-01 | 3.36e-03 | 1.000000 |
| REACTOME HEDGEHOG ON STATE | 85 | 9.68e-01 | -2.54e-03 | 1.000000 |
| REACTOME SUPPRESSION OF PHAGOSOMAL MATURATION | 13 | 9.68e-01 | -6.46e-03 | 1.000000 |
| REACTOME NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 19 | 9.68e-01 | -5.33e-03 | 1.000000 |
| REACTOME SIGNALING BY MRAS COMPLEX MUTANTS | 7 | 9.70e-01 | -8.30e-03 | 1.000000 |
| REACTOME UNFOLDED PROTEIN RESPONSE UPR | 88 | 9.70e-01 | -2.32e-03 | 1.000000 |
| REACTOME PHOSPHOLIPID METABOLISM | 201 | 9.71e-01 | 1.49e-03 | 1.000000 |
| REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | 123 | 9.71e-01 | -1.91e-03 | 1.000000 |
| REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE | 19 | 9.71e-01 | -4.78e-03 | 1.000000 |
| REACTOME RECYCLING OF EIF2 GDP | 7 | 9.72e-01 | 7.61e-03 | 1.000000 |
| REACTOME DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS | 19 | 9.73e-01 | -4.41e-03 | 1.000000 |
| REACTOME CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS | 19 | 9.74e-01 | 4.30e-03 | 1.000000 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS | 7 | 9.75e-01 | 6.87e-03 | 1.000000 |
| REACTOME HEME SIGNALING | 47 | 9.76e-01 | -2.49e-03 | 1.000000 |
| REACTOME ARMS MEDIATED ACTIVATION | 7 | 9.76e-01 | 6.44e-03 | 1.000000 |
| REACTOME PLATELET HOMEOSTASIS | 85 | 9.77e-01 | 1.83e-03 | 1.000000 |
| REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | 20 | 9.77e-01 | 3.72e-03 | 1.000000 |
| REACTOME LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX | 5 | 9.77e-01 | 7.34e-03 | 1.000000 |
| REACTOME EPH EPHRIN MEDIATED REPULSION OF CELLS | 50 | 9.77e-01 | -2.32e-03 | 1.000000 |
| REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | 19 | 9.77e-01 | -3.75e-03 | 1.000000 |
| REACTOME DOWNREGULATION OF ERBB2 SIGNALING | 29 | 9.78e-01 | 2.99e-03 | 1.000000 |
| REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING | 25 | 9.78e-01 | -3.12e-03 | 1.000000 |
| REACTOME POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE | 25 | 9.79e-01 | 3.10e-03 | 1.000000 |
| REACTOME SEMA3A PAK DEPENDENT AXON REPULSION | 14 | 9.79e-01 | 4.06e-03 | 1.000000 |
| REACTOME EXTENSION OF TELOMERES | 49 | 9.79e-01 | -2.17e-03 | 1.000000 |
| REACTOME SIGNAL TRANSDUCTION BY L1 | 20 | 9.80e-01 | -3.25e-03 | 1.000000 |
| REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX | 36 | 9.80e-01 | -2.40e-03 | 1.000000 |
| REACTOME MITOTIC SPINDLE CHECKPOINT | 109 | 9.81e-01 | 1.35e-03 | 1.000000 |
| REACTOME TRIGLYCERIDE METABOLISM | 35 | 9.81e-01 | 2.38e-03 | 1.000000 |
| REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | 39 | 9.81e-01 | -2.19e-03 | 1.000000 |
| REACTOME ACETYLCHOLINE REGULATES INSULIN SECRETION | 10 | 9.82e-01 | -4.12e-03 | 1.000000 |
| REACTOME G0 AND EARLY G1 | 27 | 9.84e-01 | 2.20e-03 | 1.000000 |
| REACTOME RHO GTPASES ACTIVATE KTN1 | 11 | 9.85e-01 | -3.30e-03 | 1.000000 |
| REACTOME PROTEIN FOLDING | 96 | 9.86e-01 | 1.07e-03 | 1.000000 |
| REACTOME HORMONE LIGAND BINDING RECEPTORS | 12 | 9.86e-01 | 2.96e-03 | 1.000000 |
| REACTOME NEF MEDIATED CD8 DOWN REGULATION | 7 | 9.86e-01 | -3.84e-03 | 1.000000 |
| REACTOME PI METABOLISM | 79 | 9.86e-01 | -1.12e-03 | 1.000000 |
| REACTOME L1CAM INTERACTIONS | 112 | 9.87e-01 | -9.18e-04 | 1.000000 |
| REACTOME SIGNALING BY NOTCH1 | 69 | 9.87e-01 | 1.13e-03 | 1.000000 |
| REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION | 6 | 9.87e-01 | 3.73e-03 | 1.000000 |
| REACTOME G ALPHA I SIGNALLING EVENTS | 304 | 9.88e-01 | 5.17e-04 | 1.000000 |
| REACTOME VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS | 42 | 9.88e-01 | -1.32e-03 | 1.000000 |
| REACTOME SIGNALING BY ERBB2 | 50 | 9.88e-01 | -1.19e-03 | 1.000000 |
| REACTOME TELOMERE C STRAND LAGGING STRAND SYNTHESIS | 33 | 9.89e-01 | 1.42e-03 | 1.000000 |
| REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE | 109 | 9.89e-01 | 7.66e-04 | 1.000000 |
| REACTOME EFFECTS OF PIP2 HYDROLYSIS | 26 | 9.89e-01 | 1.55e-03 | 1.000000 |
| REACTOME FGFR1 LIGAND BINDING AND ACTIVATION | 15 | 9.89e-01 | -1.99e-03 | 1.000000 |
| REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES | 34 | 9.91e-01 | 1.11e-03 | 1.000000 |
| REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION | 74 | 9.92e-01 | 6.94e-04 | 1.000000 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH CDK5 | 6 | 9.92e-01 | 2.41e-03 | 1.000000 |
| REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE | 8 | 9.92e-01 | 2.06e-03 | 1.000000 |
| REACTOME TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS | 43 | 9.92e-01 | 8.72e-04 | 1.000000 |
| REACTOME RHOB GTPASE CYCLE | 67 | 9.92e-01 | 6.69e-04 | 1.000000 |
| REACTOME CELLULAR HEXOSE TRANSPORT | 21 | 9.92e-01 | -1.19e-03 | 1.000000 |
| REACTOME TYSND1 CLEAVES PEROXISOMAL PROTEINS | 7 | 9.93e-01 | -1.97e-03 | 1.000000 |
| REACTOME GAP JUNCTION TRAFFICKING AND REGULATION | 49 | 9.94e-01 | 6.65e-04 | 1.000000 |
| REACTOME RAC2 GTPASE CYCLE | 81 | 9.94e-01 | 4.55e-04 | 1.000000 |
| REACTOME RHO GTPASES ACTIVATE ROCKS | 19 | 9.95e-01 | 8.38e-04 | 1.000000 |
| REACTOME METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION | 15 | 9.95e-01 | -9.40e-04 | 1.000000 |
| REACTOME ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA | 9 | 9.96e-01 | -1.07e-03 | 1.000000 |
| REACTOME AMINO ACID CONJUGATION | 9 | 9.97e-01 | -7.98e-04 | 1.000000 |
| REACTOME WAX AND PLASMALOGEN BIOSYNTHESIS | 5 | 9.97e-01 | 1.02e-03 | 1.000000 |
| REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX IN CANCER | 8 | 9.97e-01 | -6.59e-04 | 1.000000 |
| REACTOME METABOLISM OF STEROID HORMONES | 35 | 9.98e-01 | 2.83e-04 | 1.000000 |
| REACTOME DSCAM INTERACTIONS | 11 | 9.98e-01 | 5.04e-04 | 1.000000 |
| REACTOME XENOBIOTICS | 22 | 9.98e-01 | -3.31e-04 | 1.000000 |
| REACTOME WNT MEDIATED ACTIVATION OF DVL | 8 | 9.99e-01 | 3.41e-04 | 1.000000 |
| REACTOME REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM | 11 | 9.99e-01 | 2.81e-04 | 1.000000 |
| REACTOME INACTIVATION OF CDC42 AND RAC1 | 8 | 9.99e-01 | -2.39e-04 | 1.000000 |
| REACTOME NUCLEAR IMPORT OF REV PROTEIN | 34 | 9.99e-01 | 9.37e-05 | 1.000000 |
| REACTOME SUMO IS PROTEOLYTICALLY PROCESSED | 6 | 1.00e+00 | -4.55e-05 | 1.000000 |
| REACTOME SODIUM COUPLED PHOSPHATE COTRANSPORTERS | 5 | 1.00e+00 | -1.82e-05 | 1.000000 |
Detailed Gene set reports
REACTOME_NEUTROPHIL_DEGRANULATION
| 1053 | |
|---|---|
| set | REACTOME_NEUTROPHIL_DEGRANULATION |
| setSize | 460 |
| pANOVA | 3.99e-07 |
| s.dist | -0.138 |
| p.adjustANOVA | 0.000655 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| FOLR3 | -10730 |
| RNASE2 | -10699 |
| AZU1 | -10689 |
| ADGRG3 | -10685 |
| S100A8 | -10672 |
| CEACAM6 | -10634 |
| CEACAM1 | -10608 |
| LRG1 | -10590 |
| STING1 | -10585 |
| DEFA4 | -10564 |
| RNASE3 | -10553 |
| MPO | -10502 |
| CEACAM3 | -10478 |
| LYZ | -10459 |
| MS4A3 | -10440 |
| CTSG | -10433 |
| PRTN3 | -10428 |
| TARM1 | -10420 |
| C5AR1 | -10399 |
| AOC1 | -10355 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| FOLR3 | -10730 |
| RNASE2 | -10699 |
| AZU1 | -10689 |
| ADGRG3 | -10685 |
| S100A8 | -10672 |
| CEACAM6 | -10634 |
| CEACAM1 | -10608 |
| LRG1 | -10590 |
| STING1 | -10585 |
| DEFA4 | -10564 |
| RNASE3 | -10553 |
| MPO | -10502 |
| CEACAM3 | -10478 |
| LYZ | -10459 |
| MS4A3 | -10440 |
| CTSG | -10433 |
| PRTN3 | -10428 |
| TARM1 | -10420 |
| C5AR1 | -10399 |
| AOC1 | -10355 |
| CHI3L1 | -10320 |
| FCER1G | -10315 |
| HRNR | -10287 |
| CD68 | -10278 |
| ELANE | -10234 |
| VAT1 | -10127 |
| RHOG | -10102 |
| SERPINB12 | -10094 |
| FGR | -10083 |
| OSCAR | -10053 |
| HP | -10041 |
| TMEM30A | -10036 |
| PGLYRP1 | -9918 |
| PRKCD | -9900 |
| TYROBP | -9897 |
| BRI3 | -9894 |
| CAMP | -9844 |
| FCGR2A | -9822 |
| GSTP1 | -9813 |
| GDI2 | -9783 |
| PLAUR | -9746 |
| MNDA | -9740 |
| CTSA | -9569 |
| PLD1 | -9558 |
| RAB31 | -9538 |
| NME2 | -9519 |
| PSMB7 | -9461 |
| CAP1 | -9392 |
| PLAU | -9390 |
| CLEC4D | -9381 |
| FCAR | -9371 |
| GGH | -9235 |
| ATG7 | -9202 |
| S100P | -9182 |
| SLC11A1 | -9175 |
| GUSB | -9171 |
| S100A12 | -9152 |
| OLR1 | -9136 |
| DOK3 | -9086 |
| CAT | -9061 |
| GMFG | -8982 |
| CDA | -8952 |
| HGSNAT | -8948 |
| PTPRJ | -8915 |
| RAB27A | -8899 |
| MGST1 | -8871 |
| VNN1 | -8742 |
| SELL | -8736 |
| CXCR2 | -8734 |
| CD177 | -8700 |
| GM2A | -8683 |
| COMMD3 | -8672 |
| CTSB | -8445 |
| FCN1 | -8441 |
| PRG2 | -8415 |
| GSN | -8413 |
| FTH1 | -8379 |
| TNFAIP6 | -8375 |
| KPNB1 | -8302 |
| SLC2A3 | -8247 |
| LAMTOR1 | -8223 |
| SERPINB10 | -8195 |
| HLA-B | -8160 |
| CREG1 | -8154 |
| VCP | -8003 |
| BIN2 | -7947 |
| IMPDH1 | -7905 |
| VPS35L | -7886 |
| DIAPH1 | -7877 |
| ANXA2 | -7876 |
| P2RX1 | -7860 |
| RAB10 | -7857 |
| ATP6V0A1 | -7842 |
| HSPA1B | -7567 |
| PNP | -7558 |
| MME | -7549 |
| SIRPB1 | -7476 |
| COMMD9 | -7368 |
| CTSD | -7359 |
| PPIA | -7358 |
| CPNE3 | -7304 |
| TCN1 | -7300 |
| AMPD3 | -7266 |
| CD63 | -7112 |
| ATP8B4 | -7013 |
| DYNLL1 | -7006 |
| CEACAM8 | -6890 |
| PTX3 | -6847 |
| SERPINB1 | -6787 |
| CYB5R3 | -6780 |
| HLA-A | -6748 |
| ADA2 | -6710 |
| ACTR1B | -6552 |
| PGAM1 | -6436 |
| AP1M1 | -6431 |
| HEXB | -6399 |
| CFD | -6393 |
| GCA | -6390 |
| CD59 | -6368 |
| MMP8 | -6357 |
| LAMTOR2 | -6295 |
| RAP2B | -6278 |
| SCAMP1 | -6275 |
| HSPA1A | -6254 |
| SLCO4C1 | -6175 |
| LTA4H | -6130 |
| DBNL | -6057 |
| MMP9 | -6001 |
| CRACR2A | -5970 |
| RAB37 | -5913 |
| SIGLEC5 | -5797 |
| OSTF1 | -5796 |
| CD44 | -5772 |
| GYG1 | -5761 |
| RAB3D | -5558 |
| CTSS | -5542 |
| CR1 | -5511 |
| FAF2 | -5496 |
| ACLY | -5445 |
| CMTM6 | -5421 |
| CPNE1 | -5410 |
| HSP90AB1 | -5393 |
| NHLRC3 | -5344 |
| ITGAM | -5303 |
| KCNAB2 | -5277 |
| PSMC2 | -5276 |
| DSN1 | -5261 |
| XRCC6 | -5223 |
| UBR4 | -5212 |
| CD93 | -5139 |
| ADAM10 | -5133 |
| DNAJC13 | -5091 |
| TRPM2 | -5088 |
| B4GALT1 | -4984 |
| IQGAP2 | -4963 |
| COTL1 | -4953 |
| S100A9 | -4899 |
| ALOX5 | -4854 |
| ALAD | -4830 |
| GNS | -4789 |
| PADI2 | -4759 |
| LAIR1 | -4719 |
| CLEC12A | -4689 |
| CD58 | -4608 |
| PRG3 | -4566 |
| SERPINA1 | -4564 |
| MLEC | -4561 |
| PLEKHO2 | -4522 |
| B2M | -4432 |
| AGA | -4285 |
| RAP1B | -4260 |
| ARMC8 | -4236 |
| PTPN6 | -4209 |
| CLEC5A | -4078 |
| SLC2A5 | -3938 |
| MCEMP1 | -3937 |
| FLG2 | -3911 |
| RAB24 | -3909 |
| FCGR3B | -3883 |
| KCMF1 | -3826 |
| PSMB1 | -3823 |
| CRISPLD2 | -3820 |
| RAB6A | -3704 |
| RAB5B | -3673 |
| DNAJC3 | -3652 |
| PSMD14 | -3626 |
| CTSZ | -3612 |
| SYNGR1 | -3560 |
| RAB44 | -3520 |
| GPI | -3519 |
| CD47 | -3500 |
| TICAM2 | -3487 |
| CYSTM1 | -3464 |
| PKM | -3388 |
| KRT1 | -3356 |
| SLPI | -3192 |
| ABCA13 | -3186 |
| TUBB | -3184 |
| NCKAP1L | -3124 |
| HSPA6 | -3044 |
| BPI | -2999 |
| PSMA5 | -2988 |
| GSDMD | -2968 |
| ITGAV | -2938 |
| PSAP | -2877 |
| PSEN1 | -2862 |
| STOM | -2841 |
| PSMA2 | -2839 |
| ARSB | -2742 |
| DERA | -2692 |
| CD33 | -2590 |
| SVIP | -2550 |
| SERPINB6 | -2519 |
| IGF2R | -2499 |
| IST1 | -2487 |
| STK11IP | -2393 |
| UNC13D | -2377 |
| FRK | -2320 |
| TTR | -2303 |
| FPR2 | -2152 |
| HPSE | -2071 |
| BST1 | -2038 |
| LTF | -1996 |
| FGL2 | -1977 |
| XRCC5 | -1920 |
| DDOST | -1885 |
| ADAM8 | -1879 |
| EEF1A1 | -1701 |
| CAB39 | -1672 |
| LRRC7 | -1511 |
| ITGAL | -1475 |
| SNAP25 | -1456 |
| CANT1 | -1403 |
| ARL8A | -1355 |
| GRN | -1287 |
| S100A11 | -1262 |
| ITGAX | -1167 |
| C6orf120 | -1136 |
| YPEL5 | -1009 |
| GALNS | -884 |
| PSMD7 | -880 |
| EPX | -857 |
| GHDC | -834 |
| PTPRB | -815 |
| LILRB2 | -741 |
| DYNC1H1 | -731 |
| PRCP | -719 |
| VAPA | -699 |
| VAMP8 | -678 |
| RAB18 | -634 |
| SNAP23 | -622 |
| ALDH3B1 | -618 |
| HSPA8 | -515 |
| PYCARD | -512 |
| PSMD1 | -503 |
| IMPDH2 | -493 |
| ANO6 | -477 |
| QSOX1 | -473 |
| TXNDC5 | -445 |
| HMOX2 | -399 |
| DNAJC5 | -348 |
| LGALS3 | -264 |
| RAC1 | -259 |
| NFKB1 | -235 |
| MAPK14 | -206 |
| MMP25 | -171 |
| PTPRN2 | -50 |
| TMBIM1 | 161 |
| FUCA2 | 182 |
| TMEM63A | 184 |
| ADGRE3 | 237 |
| FABP5 | 264 |
| MIF | 376 |
| AGL | 467 |
| IDH1 | 534 |
| ERP44 | 625 |
| PLAC8 | 649 |
| VCL | 680 |
| RAB4B | 792 |
| CST3 | 888 |
| CPPED1 | 991 |
| DYNLT1 | 992 |
| NCSTN | 1050 |
| FTL | 1190 |
| DOCK2 | 1202 |
| PKP1 | 1237 |
| CKAP4 | 1283 |
| SURF4 | 1303 |
| ROCK1 | 1369 |
| STBD1 | 1392 |
| GLIPR1 | 1406 |
| RHOA | 1452 |
| C1orf35 | 1470 |
| APRT | 1471 |
| SERPINA3 | 1483 |
| TSPAN14 | 1526 |
| PDXK | 1546 |
| CAPN1 | 1603 |
| SPTAN1 | 1620 |
| ATP11B | 1664 |
| PPIE | 1675 |
| ALDOC | 1836 |
| TLR2 | 1838 |
| PFKL | 1843 |
| NEU1 | 1873 |
| LCN2 | 1918 |
| DSP | 1946 |
| ATP11A | 1964 |
| PSMD3 | 1999 |
| TIMP2 | 2020 |
| RAB5C | 2107 |
| C3AR1 | 2137 |
| NIT2 | 2157 |
| PSMD6 | 2217 |
| CNN2 | 2223 |
| DYNC1LI1 | 2238 |
| CEP290 | 2251 |
| PGM1 | 2264 |
| ARG1 | 2322 |
| PAFAH1B2 | 2353 |
| DGAT1 | 2480 |
| ATP6V1D | 2563 |
| HLA-C | 2564 |
| CTSH | 2588 |
| CSNK2B | 2620 |
| RAB3A | 2728 |
| DEGS1 | 2758 |
| CRISP3 | 2776 |
| FUCA1 | 2859 |
| HEBP2 | 2883 |
| ATP6V0C | 2912 |
| ARPC5 | 3014 |
| CD36 | 3062 |
| RAP1A | 3156 |
| APAF1 | 3179 |
| PYGL | 3320 |
| BST2 | 3333 |
| PSMD11 | 3372 |
| HSP90AA1 | 3411 |
| STK10 | 3518 |
| NFAM1 | 3573 |
| PDAP1 | 3817 |
| ASAH1 | 3834 |
| QPCT | 3842 |
| AHSG | 3894 |
| IRAG2 | 3948 |
| PSMD12 | 4000 |
| CYFIP1 | 4008 |
| RAB14 | 4015 |
| CLEC4C | 4130 |
| ATP8A1 | 4145 |
| PTGES2 | 4172 |
| TOLLIP | 4192 |
| C3 | 4206 |
| RAB7A | 4213 |
| HBB | 4251 |
| NRAS | 4302 |
| PRDX6 | 4363 |
| COPB1 | 4367 |
| MANBA | 4471 |
| CXCL1 | 4673 |
| SRP14 | 4708 |
| DPP7 | 4727 |
| CDK13 | 4742 |
| SNAP29 | 4903 |
| MAN2B1 | 4934 |
| TOM1 | 5045 |
| CCT2 | 5055 |
| ACTR10 | 5067 |
| RNASET2 | 5093 |
| GOLGA7 | 5152 |
| IQGAP1 | 5259 |
| ALDOA | 5361 |
| MAPK1 | 5363 |
| FPR1 | 5395 |
| HVCN1 | 5418 |
| CALML5 | 5500 |
| LAMTOR3 | 5509 |
| DSG1 | 5521 |
| MGAM | 5543 |
| PSMC3 | 5595 |
| GPR84 | 5663 |
| LILRA3 | 5722 |
| LPCAT1 | 5808 |
| NDUFC2 | 6199 |
| ARSA | 6207 |
| SDCBP | 6255 |
| PIGR | 6364 |
| TMEM179B | 6483 |
| PSMD13 | 6561 |
| TRAPPC1 | 6626 |
| TNFRSF1B | 6635 |
| CD14 | 6783 |
| ADGRE5 | 6831 |
| GLB1 | 6882 |
| PSMD2 | 6891 |
| APEH | 6925 |
| PRSS3 | 6935 |
| PGM2 | 7027 |
| RETN | 7175 |
| ITGB2 | 7233 |
| CXCR1 | 7413 |
| RHOF | 7439 |
| CAND1 | 7509 |
| CHIT1 | 7527 |
| ORM2 | 7565 |
| JUP | 7590 |
| ARHGAP9 | 7661 |
| CD55 | 7720 |
| NBEAL2 | 7759 |
| LAMP1 | 7760 |
| PYGB | 7771 |
| ACAA1 | 7800 |
| AP2A2 | 7870 |
| CCT8 | 7910 |
| TMC6 | 7923 |
| ORM1 | 7991 |
| TUBB4B | 8016 |
| PTAFR | 8064 |
| ACTR2 | 8183 |
| HMGB1 | 8187 |
| ARHGAP45 | 8275 |
| NAPRT | 8285 |
| ANPEP | 8396 |
| PTPRC | 8415 |
| AGPAT2 | 8504 |
| ORMDL3 | 8553 |
| LILRB3 | 8576 |
| ILF2 | 8698 |
| GAA | 8699 |
| ENPP4 | 8733 |
| NPC2 | 8779 |
| TCIRG1 | 8803 |
| SLC44A2 | 8884 |
| CHRNB4 | 9093 |
| ATAD3B | 9130 |
| CTSC | 9181 |
| HK3 | 9215 |
| EEF2 | 9252 |
| PA2G4 | 9263 |
| CYBA | 9369 |
| CD53 | 9379 |
| SERPINB3 | 9391 |
| CSTB | 9504 |
| ACP3 | 9557 |
| PPBP | 9586 |
| MVP | 9625 |
| SLC27A2 | 9658 |
| DSC1 | 9667 |
| SIRPA | 9677 |
| NFASC | 9696 |
| SIGLEC9 | 9757 |
| CD300A | 9871 |
| OLFM4 | 9957 |
| TBC1D10C | 10352 |
| A1BG | 10369 |
| SIGLEC14 | 10426 |
| S100A7 | 10858 |
| PECAM1 | 10936 |
| SLC15A4 | 11038 |
REACTOME_KERATINIZATION
| 1073 | |
|---|---|
| set | REACTOME_KERATINIZATION |
| setSize | 210 |
| pANOVA | 9.49e-07 |
| s.dist | 0.196 |
| p.adjustANOVA | 0.000779 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| KRTAP3-3 | 11229 |
| KRTAP2-3 | 11112 |
| SPRR2E | 11084 |
| KRTAP4-6 | 11076 |
| KRTAP1-4 | 11021 |
| KRTAP12-4 | 10998 |
| KRT80 | 10940 |
| KRTAP5-1 | 10912 |
| KRTAP9-3 | 10893 |
| SPRR1B | 10883 |
| KRTAP5-8 | 10785 |
| KRTAP5-2 | 10724 |
| KRTAP9-9 | 10660 |
| KRTAP10-6 | 10592 |
| LCE3A | 10570 |
| SPINK9 | 10559 |
| KRTAP10-8 | 10528 |
| KRTAP5-9 | 10491 |
| KRTAP5-4 | 10481 |
| KRTAP21-2 | 10427 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| KRTAP3-3 | 11229.0 |
| KRTAP2-3 | 11112.0 |
| SPRR2E | 11084.0 |
| KRTAP4-6 | 11076.0 |
| KRTAP1-4 | 11021.0 |
| KRTAP12-4 | 10998.0 |
| KRT80 | 10940.0 |
| KRTAP5-1 | 10912.0 |
| KRTAP9-3 | 10893.0 |
| SPRR1B | 10883.0 |
| KRTAP5-8 | 10785.0 |
| KRTAP5-2 | 10724.0 |
| KRTAP9-9 | 10660.0 |
| KRTAP10-6 | 10592.0 |
| LCE3A | 10570.0 |
| SPINK9 | 10559.0 |
| KRTAP10-8 | 10528.0 |
| KRTAP5-9 | 10491.0 |
| KRTAP5-4 | 10481.0 |
| KRTAP21-2 | 10427.0 |
| CDSN | 10382.0 |
| KRTAP4-4 | 10350.0 |
| KRT15 | 10331.0 |
| KRT4 | 10330.0 |
| KRT85 | 10328.0 |
| KRTAP19-1 | 10319.0 |
| KRT24 | 10314.0 |
| KRTAP21-1 | 10250.0 |
| KLK14 | 10249.0 |
| KRTAP5-11 | 10247.0 |
| KRT37 | 10193.0 |
| KRTAP19-7 | 10190.0 |
| KRT28 | 10139.0 |
| IVL | 10061.0 |
| KRT14 | 9979.0 |
| KRT33A | 9970.0 |
| KRTAP4-2 | 9849.0 |
| KRT33B | 9839.0 |
| LIPK | 9746.0 |
| KRTAP13-3 | 9707.0 |
| DSG3 | 9698.0 |
| KRT75 | 9692.0 |
| DSC1 | 9667.0 |
| KRTAP10-2 | 9650.0 |
| KRT35 | 9613.0 |
| KRTAP20-2 | 9569.0 |
| KRT13 | 9509.0 |
| KRT71 | 9470.0 |
| KRTAP10-7 | 9414.0 |
| LCE1B | 9399.0 |
| LIPJ | 9346.0 |
| KRTAP17-1 | 9321.0 |
| DSG4 | 9214.0 |
| KRTAP1-1 | 9193.0 |
| KRTAP12-3 | 9157.0 |
| KRTAP10-9 | 9115.0 |
| KRT32 | 9030.0 |
| KRT23 | 8973.0 |
| LIPN | 8935.0 |
| SPINK5 | 8908.0 |
| CASP14 | 8765.0 |
| KRTAP4-11 | 8680.0 |
| KRT27 | 8637.0 |
| KRT36 | 8449.0 |
| KRT6C | 8414.0 |
| PKP3 | 8407.0 |
| SPRR2F | 8406.0 |
| PPL | 8227.0 |
| KRTAP2-1 | 8127.0 |
| SPRR2D | 8090.0 |
| KRT81 | 8021.0 |
| KRT26 | 7983.0 |
| KRTAP21-3 | 7805.0 |
| KRTAP19-6 | 7791.0 |
| KRTAP4-8 | 7718.0 |
| KRT31 | 7716.0 |
| JUP | 7590.0 |
| KRTAP6-2 | 7388.0 |
| KRT20 | 7244.0 |
| KRTAP5-5 | 7141.0 |
| KRTAP1-3 | 7038.0 |
| KRT38 | 7037.0 |
| KRTAP24-1 | 6938.0 |
| LELP1 | 6811.0 |
| KRTAP5-7 | 6777.0 |
| SPRR2G | 6718.0 |
| KRT7 | 6620.0 |
| KRT79 | 6556.0 |
| SPRR2A | 6152.0 |
| KRT16 | 6020.0 |
| KRTAP4-3 | 5911.0 |
| KRT5 | 5687.0 |
| KRT73 | 5682.0 |
| DSG1 | 5521.0 |
| ST14 | 5446.0 |
| KRTAP10-4 | 5322.0 |
| PCSK6 | 5296.0 |
| SPRR1A | 5274.0 |
| LIPM | 5210.0 |
| TCHH | 4976.0 |
| KRT77 | 4891.0 |
| LCE1F | 4759.0 |
| KRT76 | 4625.0 |
| LCE3B | 4544.0 |
| KRTAP2-2 | 4447.0 |
| KRT25 | 4352.0 |
| KRT74 | 4289.0 |
| KRTAP3-1 | 4275.0 |
| PI3 | 4120.0 |
| LCE2B | 4087.0 |
| LCE3E | 3969.0 |
| KRTAP5-3 | 3869.0 |
| TGM1 | 3797.0 |
| LCE4A | 3574.0 |
| KLK8 | 3510.0 |
| KLK12 | 2802.0 |
| FURIN | 2781.0 |
| KRTAP15-1 | 2657.0 |
| LCE2C | 2561.0 |
| DSP | 1946.0 |
| KRTAP26-1 | 1914.0 |
| KRTAP10-5 | 1723.0 |
| CAPN1 | 1603.0 |
| KRTAP19-5 | 1541.0 |
| KRTAP2-4 | 1440.0 |
| KRT19 | 1240.0 |
| PKP1 | 1237.0 |
| KRT8 | 790.0 |
| PKP4 | 716.0 |
| KRT2 | 156.0 |
| KLK5 | -100.0 |
| KRTAP19-2 | -309.0 |
| LCE1A | -635.0 |
| KRT86 | -638.0 |
| DSG2 | -663.0 |
| KRTAP4-5 | -690.0 |
| KRTAP3-2 | -810.0 |
| LCE1E | -821.0 |
| KRT12 | -930.0 |
| KAZN | -992.0 |
| KRTAP6-1 | -1358.0 |
| EVPL | -1522.0 |
| KRTAP10-11 | -1881.0 |
| LCE2A | -1962.0 |
| TGM5 | -2211.0 |
| KRTAP12-2 | -2333.0 |
| KRTAP10-3 | -2551.0 |
| LCE1C | -2561.0 |
| KRT72 | -2905.0 |
| KRTAP8-1 | -2982.0 |
| PRSS8 | -3016.0 |
| KRTAP29-1 | -3096.0 |
| CELA2A | -3244.0 |
| SPRR3 | -3302.0 |
| KRT9 | -3332.0 |
| KRT1 | -3356.0 |
| KRT82 | -3446.0 |
| KRT78 | -3518.0 |
| KRTAP19-8 | -4085.0 |
| KRTAP4-1 | -4504.0 |
| KRTAP9-4 | -4592.0 |
| KRTAP9-2 | -4643.0 |
| KRTAP6-3 | -4665.0 |
| KRTAP13-1 | -4748.0 |
| KRT83 | -4838.0 |
| KRT3 | -4938.0 |
| CAPNS1 | -5563.0 |
| KRTAP10-1 | -5852.0 |
| PERP | -5957.0 |
| KRTAP22-1 | -6158.0 |
| KRT10 | -6217.0 |
| KRTAP19-3 | -6391.0 |
| KRTAP20-1 | -7011.0 |
| KRTAP23-1 | -7026.0 |
| KRTAP1-5 | -7237.0 |
| LCE5A | -7270.0 |
| KRT39 | -7450.0 |
| KLK13 | -7580.0 |
| KRT34 | -7663.0 |
| KRTAP12-1 | -7822.0 |
| KRTAP27-1 | -8073.0 |
| LCE6A | -8100.0 |
| FLG | -8131.0 |
| SPINK6 | -8257.0 |
| KRT6A | -8629.0 |
| KRT6B | -8791.0 |
| KRT18 | -8822.0 |
| CSTA | -8828.0 |
| KRT40 | -8907.0 |
| KRTAP9-6 | -8973.0 |
| DSC2 | -9070.0 |
| KRT84 | -9248.0 |
| RPTN | -9276.0 |
| DSC3 | -9286.0 |
| KRTAP19-4 | -9361.0 |
| KRTAP25-1 | -9364.0 |
| LCE3D | -9386.0 |
| KRTAP13-4 | -9710.0 |
| LCE2D | -9792.0 |
| KRTAP11-1 | -9930.0 |
| KRTAP4-7 | -9948.0 |
| KRTAP10-12 | -9991.0 |
| KRTAP5-6 | -10131.0 |
| KRTAP10-10 | -10142.0 |
| PKP2 | -10181.0 |
| KRTAP13-2 | -10230.0 |
| KRTAP9-1 | -10324.0 |
| KRTAP5-10 | -10472.5 |
| KRTAP16-1 | -10654.0 |
| KRT17 | -10723.0 |
REACTOME_SENSORY_PERCEPTION
| 1581 | |
|---|---|
| set | REACTOME_SENSORY_PERCEPTION |
| setSize | 555 |
| pANOVA | 8.93e-06 |
| s.dist | 0.11 |
| p.adjustANOVA | 0.00489 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| OR10H2 | 11246 |
| OR52E6 | 11236 |
| OR51V1 | 11185 |
| OR2T3 | 11166 |
| OR7D4 | 11139 |
| OR7A10 | 11125 |
| OR56B4 | 11111 |
| OR5M3 | 11094 |
| OR5T2 | 11049 |
| OR52H1 | 11042 |
| OR2AK2 | 10946 |
| CALHM3 | 10920 |
| AKR1B10 | 10915 |
| OR10Z1 | 10899 |
| OR2T33 | 10894 |
| OR13G1 | 10850 |
| OR4A5 | 10821 |
| OR52N1 | 10820 |
| OR2V1 | 10802 |
| OR13J1 | 10797 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| OR10H2 | 11246.0 |
| OR52E6 | 11236.0 |
| OR51V1 | 11185.0 |
| OR2T3 | 11166.0 |
| OR7D4 | 11139.0 |
| OR7A10 | 11125.0 |
| OR56B4 | 11111.0 |
| OR5M3 | 11094.0 |
| OR5T2 | 11049.0 |
| OR52H1 | 11042.0 |
| OR2AK2 | 10946.0 |
| CALHM3 | 10920.0 |
| AKR1B10 | 10915.0 |
| OR10Z1 | 10899.0 |
| OR2T33 | 10894.0 |
| OR13G1 | 10850.0 |
| OR4A5 | 10821.0 |
| OR52N1 | 10820.0 |
| OR2V1 | 10802.0 |
| OR13J1 | 10797.0 |
| OR10H5 | 10795.0 |
| OR6B2 | 10784.0 |
| OR2H2 | 10771.0 |
| OR52E2 | 10714.0 |
| OR2L2 | 10708.0 |
| OR6N2 | 10696.0 |
| OR4N2 | 10669.0 |
| OR6C65 | 10662.0 |
| PDE6G | 10653.0 |
| OR10G2 | 10650.0 |
| OR6C6 | 10588.0 |
| RPE65 | 10551.0 |
| APOB | 10547.0 |
| TRPM4 | 10496.0 |
| OR2A2 | 10488.0 |
| OR6K3 | 10483.0 |
| APOA4 | 10458.0 |
| OR5K4 | 10456.0 |
| OR2T27 | 10418.0 |
| OR4D10 | 10413.0 |
| OR2Y1 | 10389.0 |
| OR14C36 | 10375.0 |
| TRPM5 | 10360.0 |
| OR52A5 | 10353.0 |
| TAS2R43 | 10342.0 |
| OR1A2 | 10325.0 |
| GNAT3 | 10290.0 |
| OR52K1 | 10280.0 |
| KCNMB1 | 10278.0 |
| OR4D6 | 10276.0 |
| STRA6 | 10262.0 |
| RDH5 | 10229.0 |
| MYH9 | 10221.0 |
| OR1E1 | 10200.0 |
| OR10A6 | 10172.0 |
| OR2T12 | 10171.0 |
| LRP10 | 10152.0 |
| OR2M3 | 10140.0 |
| OR5D13 | 10099.0 |
| OR4B1 | 10088.0 |
| OR6C74 | 10073.0 |
| AKR1C1 | 10063.0 |
| OR2G6 | 10059.0 |
| OR11G2 | 10037.0 |
| RTP1 | 10025.0 |
| OR52A1 | 9995.0 |
| OR10G3 | 9977.0 |
| CAPZA2 | 9928.0 |
| OR10K2 | 9862.0 |
| OR2L3 | 9847.0 |
| OR5T3 | 9792.0 |
| SDR9C7 | 9771.0 |
| TAS2R46 | 9767.0 |
| OR6C1 | 9726.0 |
| OR2D3 | 9717.0 |
| OR10G9 | 9614.0 |
| OR6C3 | 9573.0 |
| OR1J4 | 9566.0 |
| OR5AR1 | 9551.0 |
| OR10H4 | 9549.0 |
| OR11H6 | 9532.0 |
| OR51F2 | 9516.0 |
| APOM | 9496.0 |
| RBP3 | 9474.0 |
| GNB3 | 9461.0 |
| TAS1R1 | 9455.0 |
| OR6C2 | 9443.0 |
| OR1N1 | 9402.0 |
| OR2A14 | 9374.0 |
| SLC17A8 | 9333.0 |
| OR51Q1 | 9325.0 |
| OR4K5 | 9304.0 |
| OR2K2 | 9301.0 |
| OR6C4 | 9274.0 |
| ESPNL | 9230.0 |
| OR5K2 | 9223.0 |
| OR1A1 | 9196.0 |
| RLBP1 | 9191.0 |
| XIRP2 | 9187.0 |
| OR2T8 | 9185.0 |
| OR6F1 | 9178.0 |
| OR5J2 | 9124.0 |
| OR4K2 | 9084.0 |
| OR51B2 | 9075.0 |
| REEP1 | 9073.0 |
| OR4N5 | 9046.0 |
| OR2F2 | 9013.0 |
| MYO15A | 9006.0 |
| OR6N1 | 8970.0 |
| OR9Q2 | 8960.0 |
| OR6C68 | 8943.0 |
| OR5A2 | 8919.0 |
| OR10AD1 | 8810.0 |
| TAS1R3 | 8800.0 |
| OR13C9 | 8774.0 |
| OR4C3 | 8726.0 |
| OR5AN1 | 8701.0 |
| OR2T6 | 8685.0 |
| OR52M1 | 8669.0 |
| OR52W1 | 8662.0 |
| OR10X1 | 8644.0 |
| EPB41L1 | 8603.0 |
| ATP2B2 | 8590.0 |
| OR2H1 | 8577.0 |
| OR9G4 | 8541.0 |
| OR8U1 | 8527.0 |
| CALHM1 | 8525.0 |
| OR9A2 | 8523.0 |
| OR14J1 | 8502.0 |
| OR7C1 | 8485.0 |
| GRK4 | 8423.0 |
| OR9Q1 | 8400.0 |
| OR8J1 | 8290.0 |
| OR5L1 | 8281.0 |
| PLB1 | 8258.0 |
| CHRNA9 | 8255.0 |
| GPC1 | 8168.0 |
| OR10S1 | 8128.0 |
| TAS1R2 | 8084.0 |
| OR6Q1 | 8006.0 |
| GNG13 | 7984.0 |
| TAS2R14 | 7912.0 |
| HSD17B1 | 7899.0 |
| OR10T2 | 7849.0 |
| OR51B5 | 7847.0 |
| OR14I1 | 7829.0 |
| GRM4 | 7740.0 |
| BSN | 7675.0 |
| OR3A3 | 7560.0 |
| OTOF | 7521.0 |
| OR6B1 | 7463.0 |
| RIPOR2 | 7407.0 |
| OR10K1 | 7382.0 |
| OR10H1 | 7375.0 |
| OTOG | 7372.0 |
| OR1B1 | 7350.0 |
| OR2F1 | 7280.0 |
| APOC3 | 7217.0 |
| OR1G1 | 7207.0 |
| PLS1 | 7199.0 |
| LRP1 | 7098.0 |
| OR5F1 | 7052.0 |
| SCN3A | 6896.0 |
| OR4X1 | 6845.0 |
| OR56A4 | 6835.0 |
| SLC24A1 | 6763.0 |
| METAP2 | 6746.0 |
| OR51G2 | 6653.0 |
| GPIHBP1 | 6629.0 |
| CIB2 | 6624.0 |
| APOA1 | 6606.0 |
| OR11H4 | 6591.0 |
| SCN9A | 6551.0 |
| SCN4B | 6550.0 |
| OR4K14 | 6532.0 |
| OR9K2 | 6511.0 |
| TMC2 | 6503.0 |
| LDB1 | 6482.0 |
| OR1C1 | 6480.0 |
| SDC4 | 6457.0 |
| OR52I1 | 6441.0 |
| TWF2 | 6429.0 |
| OR2T4 | 6388.0 |
| OR2L5 | 6371.0 |
| OR5AU1 | 6365.0 |
| OR10A2 | 6305.0 |
| TAS2R50 | 6281.0 |
| BCO2 | 6257.0 |
| OR2Z1 | 6231.0 |
| NMT2 | 6134.0 |
| CDH23 | 6032.0 |
| OR4C15 | 5934.0 |
| APOE | 5919.0 |
| PRKCQ | 5824.0 |
| OR5H6 | 5684.0 |
| OR5H15 | 5674.0 |
| OR5H1 | 5591.0 |
| FNTB | 5549.0 |
| OR5W2 | 5531.0 |
| DHRS3 | 5393.0 |
| AKR1C4 | 5346.0 |
| KCNQ4 | 5343.0 |
| OR7C2 | 5301.0 |
| OR8I2 | 5263.0 |
| OR5H2 | 5253.0 |
| OR2L13 | 5249.0 |
| SCNN1D | 5241.0 |
| TAS2R20 | 5201.0 |
| EPS8L2 | 5188.0 |
| OR8B12 | 5185.0 |
| GPC2 | 5173.0 |
| OR5T1 | 5108.0 |
| PCDH15 | 5095.0 |
| MYO7A | 5070.0 |
| OR10J1 | 5043.0 |
| OR8G1 | 4986.0 |
| GNGT1 | 4980.0 |
| OR5D18 | 4952.0 |
| FNTA | 4900.0 |
| OR8K5 | 4889.0 |
| ACTB | 4881.0 |
| GRK7 | 4863.0 |
| OR1L8 | 4850.0 |
| OR10V1 | 4840.0 |
| RTP2 | 4785.0 |
| MYO3B | 4760.0 |
| CTBP2 | 4739.0 |
| OR2J2 | 4717.0 |
| OR2C3 | 4711.0 |
| OR1L6 | 4709.0 |
| OR51S1 | 4684.0 |
| SCN2B | 4666.0 |
| OR1F1 | 4664.0 |
| RDH8 | 4636.0 |
| PDE6B | 4547.0 |
| OR7G2 | 4489.0 |
| OR10W1 | 4472.0 |
| TMC1 | 4362.0 |
| GRXCR1 | 4326.0 |
| TAS2R38 | 4323.0 |
| OR4K17 | 4297.0 |
| EZR | 4219.0 |
| TAS2R39 | 4196.0 |
| AGRN | 4176.0 |
| CACNA1D | 4069.0 |
| OR8J3 | 4065.0 |
| OR4S1 | 4016.0 |
| GUCA1B | 3906.0 |
| RBP1 | 3872.0 |
| OR2G3 | 3780.0 |
| CLPS | 3744.0 |
| OR1D2 | 3714.0 |
| USH1C | 3696.0 |
| OR11A1 | 3674.0 |
| NAPEPLD | 3481.0 |
| OR4F15 | 3434.0 |
| OR2M2 | 3407.0 |
| GPC6 | 3392.0 |
| NMT1 | 3380.0 |
| GUCA1A | 3341.0 |
| TAS2R8 | 3322.0 |
| OR52E8 | 3239.0 |
| TPRN | 3230.0 |
| OR2AG1 | 3172.0 |
| OR10A5 | 3151.0 |
| OR13C4 | 3148.0 |
| OR6K6 | 3144.0 |
| RDH16 | 3096.0 |
| OR52D1 | 3094.0 |
| EBF1 | 2954.0 |
| OR56A3 | 2875.0 |
| OR7A17 | 2839.0 |
| OR2W1 | 2799.0 |
| TRIOBP | 2759.0 |
| CLIC5 | 2754.0 |
| RAB3A | 2728.0 |
| RGS9 | 2692.0 |
| OR2C1 | 2524.0 |
| SCNN1A | 2460.0 |
| GUCY2D | 2458.0 |
| CNGA1 | 2432.0 |
| LRP12 | 2412.0 |
| RBP2 | 2362.0 |
| OR4D5 | 2335.0 |
| RDH11 | 2328.0 |
| OR10A4 | 2321.0 |
| OR7D2 | 2302.0 |
| OR6B3 | 2301.0 |
| RDH10 | 2246.0 |
| OR5L2 | 2210.0 |
| GRK1 | 2182.0 |
| OR1I1 | 2161.0 |
| OR2AP1 | 2117.0 |
| OR2B3 | 2040.0 |
| OR8K3 | 1942.0 |
| OR5C1 | 1926.0 |
| RDX | 1897.0 |
| OR2AG2 | 1782.0 |
| OR4C12 | 1736.0 |
| METAP1 | 1655.0 |
| OR12D3 | 1623.0 |
| SPTAN1 | 1620.0 |
| USH1G | 1538.0 |
| OR2AE1 | 1528.0 |
| OR5AP2 | 1488.0 |
| CYP4V2 | 1466.0 |
| SCNN1G | 1433.0 |
| OR8D4 | 1388.0 |
| OR5B3 | 1364.0 |
| OR13C3 | 1334.0 |
| ITPR3 | 1311.0 |
| OR6M1 | 1103.0 |
| OTOGL | 1086.0 |
| GUCA1C | 1049.0 |
| HSPG2 | 836.0 |
| OR7G1 | 834.0 |
| OR10A7 | 828.0 |
| OR13A1 | 825.0 |
| SPTBN1 | 782.0 |
| CAPZA1 | 740.0 |
| CAMKMT | 724.0 |
| SCN1B | 714.0 |
| WHRN | 709.0 |
| GPC5 | 638.0 |
| ATP2B1 | 618.0 |
| OR2AT4 | 500.0 |
| TAS2R3 | 455.0 |
| RCVRN | 335.0 |
| GNAT1 | 222.0 |
| CALM1 | 217.0 |
| SDC2 | 192.0 |
| FSCN2 | 177.0 |
| OR5D14 | 102.0 |
| KCNMA1 | -23.0 |
| TAS2R16 | -36.0 |
| OR2G2 | -39.0 |
| CABP2 | -310.0 |
| DNAJC5 | -348.0 |
| OR4K15 | -415.0 |
| OR5K1 | -420.0 |
| SCNN1B | -529.0 |
| OR13F1 | -599.0 |
| SCN2A | -651.0 |
| SDC1 | -681.0 |
| OR13C2 | -720.0 |
| OR1N2 | -739.0 |
| OR1J2 | -788.0 |
| OR6Y1 | -955.0 |
| CACNB2 | -1006.0 |
| ANO2 | -1050.0 |
| OTOP1 | -1068.0 |
| PCLO | -1162.0 |
| CAPZB | -1178.0 |
| LHFPL5 | -1193.0 |
| OR10J5 | -1366.0 |
| ACTG1 | -1367.0 |
| SNAP25 | -1456.0 |
| OR1E2 | -1490.0 |
| OR5V1 | -1589.0 |
| ABCA4 | -1631.0 |
| OR4A47 | -1666.0 |
| PRKCA | -1711.0 |
| OR4L1 | -1776.0 |
| OR6C76 | -1782.0 |
| CNGB1 | -1808.0 |
| OR4M1 | -1821.0 |
| RDH12 | -1965.0 |
| STRC | -1973.0 |
| OR51L1 | -1987.0 |
| OR51E1 | -1997.0 |
| LRP2 | -2055.0 |
| MYO3A | -2117.0 |
| CACNA2D2 | -2257.0 |
| TTR | -2303.0 |
| OR5A1 | -2312.0 |
| GNAL | -2635.0 |
| PLCB2 | -2676.0 |
| EPS8 | -2822.0 |
| TAS2R1 | -2876.0 |
| OR51A7 | -2889.0 |
| OR10J3 | -2963.0 |
| OR5M9 | -3068.0 |
| OR7E24 | -3132.0 |
| OR2L8 | -3230.0 |
| OR4D11 | -3324.0 |
| ESPN | -3523.0 |
| RHO | -3541.0 |
| OR8G5 | -3741.0 |
| OR4A16 | -3750.0 |
| RGS9BP | -3765.0 |
| OR4C45 | -3867.0 |
| GRXCR2 | -3877.0 |
| OR4F6 | -3885.0 |
| SLC26A5 | -3915.0 |
| LDLR | -3968.0 |
| OR2S2 | -4202.0 |
| HSD17B6 | -4227.0 |
| TAS2R7 | -4243.0 |
| OR5D16 | -4292.0 |
| OR2B11 | -4322.0 |
| OR4X2 | -4374.0 |
| GNB5 | -4404.0 |
| OR8D2 | -4423.0 |
| OR9I1 | -4437.0 |
| AKR1C3 | -4506.0 |
| OR8K1 | -4560.0 |
| OR52B2 | -4613.0 |
| LRP8 | -4680.0 |
| OR10A3 | -4733.0 |
| LRRC52 | -4794.0 |
| OR8U8 | -5077.0 |
| CABP1 | -5105.0 |
| OR52J3 | -5144.0 |
| OR51B6 | -5214.0 |
| ADCY3 | -5265.0 |
| OR1K1 | -5333.0 |
| PJVK | -5365.0 |
| OR51M1 | -5371.0 |
| OR10Q1 | -5397.0 |
| OR52R1 | -5413.0 |
| OR1Q1 | -5428.0 |
| OR1L4 | -5567.0 |
| OR6K2 | -5586.0 |
| OR4D2 | -5589.0 |
| RETSAT | -5596.0 |
| STX1A | -5669.0 |
| OR6X1 | -5696.0 |
| LRAT | -5759.0 |
| GRM1 | -5837.0 |
| OR6C70 | -5859.0 |
| OR5AK2 | -5862.0 |
| OR7A5 | -5924.0 |
| OR4C6 | -6045.0 |
| OR1M1 | -6157.0 |
| OR3A2 | -6203.0 |
| DHRS9 | -6204.0 |
| OR1L3 | -6236.0 |
| CHRNA10 | -6239.0 |
| MYO1C | -6272.0 |
| OR12D2 | -6274.0 |
| OR8B2 | -6279.0 |
| SDC3 | -6333.0 |
| TWF1 | -6360.0 |
| OR51E2 | -6372.0 |
| TAS2R10 | -6375.0 |
| OR2M4 | -6378.0 |
| OR2A12 | -6396.0 |
| EPB41L3 | -6410.0 |
| OR5B12 | -6584.0 |
| OR6T1 | -6646.0 |
| OR3A1 | -6657.0 |
| OR10G8 | -6668.0 |
| OR1S1 | -6810.0 |
| OR2V2 | -6879.0 |
| LHX2 | -6967.0 |
| GNB1 | -7076.0 |
| KCNN2 | -7115.0 |
| OR2D2 | -7210.0 |
| OR8S1 | -7226.0 |
| OR4A15 | -7238.0 |
| OR4E2 | -7320.0 |
| OR51I1 | -7373.0 |
| OR8H3 | -7381.0 |
| CNGA4 | -7411.0 |
| OR52B6 | -7446.0 |
| OR5M10 | -7482.0 |
| LPL | -7517.0 |
| OR8H1 | -7551.0 |
| TMIE | -7621.0 |
| OR5M1 | -7641.0 |
| OR2W3 | -7692.0 |
| OR8U3 | -7776.0 |
| OR51G1 | -7883.0 |
| OR4K1 | -8024.0 |
| VAMP2 | -8045.0 |
| TAS2R4 | -8084.0 |
| OR51A2 | -8162.0 |
| TAS2R31 | -8185.0 |
| OR2T1 | -8234.0 |
| OR10H3 | -8309.0 |
| OR51B4 | -8333.0 |
| OR13C8 | -8383.0 |
| GSN | -8413.0 |
| TAS2R5 | -8577.0 |
| OR10P1 | -8580.0 |
| KCNJ2 | -8723.0 |
| OR6A2 | -8731.0 |
| OR4D1 | -8739.0 |
| OR51D1 | -8767.0 |
| SAG | -8787.0 |
| OR52E4 | -8797.0 |
| OR51I2 | -8864.0 |
| OR5M11 | -8910.0 |
| TAS2R40 | -9004.0 |
| OR6V1 | -9060.0 |
| OPN1SW | -9062.0 |
| OR5AS1 | -9091.0 |
| OR52I2 | -9134.0 |
| OR2M7 | -9150.0 |
| OR52N2 | -9162.0 |
| OR9G1 | -9178.5 |
| OR9G9 | -9178.5 |
| OR6S1 | -9206.0 |
| OR1L1 | -9209.0 |
| OR10G4 | -9217.0 |
| PDE6A | -9328.0 |
| OR2T11 | -9379.0 |
| OR5AC2 | -9384.0 |
| OR5P3 | -9385.0 |
| OR56A1 | -9414.0 |
| PNLIP | -9433.0 |
| RBP4 | -9438.0 |
| OR5B2 | -9439.0 |
| OR10AG1 | -9490.0 |
| OR5I1 | -9502.0 |
| OR13D1 | -9618.0 |
| OR2M5 | -9635.0 |
| OR9A4 | -9675.0 |
| OR11L1 | -9679.0 |
| OR6C75 | -9683.0 |
| OR8B4 | -9684.0 |
| OR5B21 | -9732.0 |
| OR2B6 | -9796.0 |
| APOC2 | -9853.0 |
| OR8B8 | -9901.0 |
| OR10C1 | -9928.0 |
| OR2A5 | -9949.0 |
| BCO1 | -9962.0 |
| TAS2R30 | -10002.0 |
| OR5M8 | -10047.0 |
| OR1J1 | -10060.0 |
| OR4C16 | -10090.0 |
| OR4K13 | -10095.0 |
| OR8D1 | -10121.0 |
| OR51T1 | -10167.0 |
| OR6P1 | -10210.0 |
| OR4D9 | -10240.0 |
| OR1S2 | -10252.0 |
| OR7G3 | -10271.0 |
| OR56B1 | -10284.0 |
| OR14A16 | -10326.0 |
| OR52K2 | -10327.0 |
| TAS2R13 | -10356.0 |
| OR5P2 | -10358.0 |
| OR8A1 | -10410.0 |
| OR5K3 | -10412.0 |
| OR2B2 | -10413.0 |
| APOA2 | -10439.0 |
| OR52L1 | -10507.0 |
| TAS2R41 | -10518.0 |
| OR5B17 | -10538.0 |
| OR10G7 | -10545.0 |
| OR56A5 | -10561.0 |
| OR4C46 | -10677.0 |
| OR51F1 | -10727.0 |
REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE
| 1082 | |
|---|---|
| set | REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE |
| setSize | 125 |
| pANOVA | 3.49e-05 |
| s.dist | 0.214 |
| p.adjustANOVA | 0.0143 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| SPRR2E | 11084 |
| KRT80 | 10940 |
| SPRR1B | 10883 |
| LCE3A | 10570 |
| SPINK9 | 10559 |
| CDSN | 10382 |
| KRT15 | 10331 |
| KRT4 | 10330 |
| KRT85 | 10328 |
| KRT24 | 10314 |
| KLK14 | 10249 |
| KRT37 | 10193 |
| KRT28 | 10139 |
| IVL | 10061 |
| KRT14 | 9979 |
| KRT33A | 9970 |
| KRT33B | 9839 |
| LIPK | 9746 |
| DSG3 | 9698 |
| KRT75 | 9692 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SPRR2E | 11084 |
| KRT80 | 10940 |
| SPRR1B | 10883 |
| LCE3A | 10570 |
| SPINK9 | 10559 |
| CDSN | 10382 |
| KRT15 | 10331 |
| KRT4 | 10330 |
| KRT85 | 10328 |
| KRT24 | 10314 |
| KLK14 | 10249 |
| KRT37 | 10193 |
| KRT28 | 10139 |
| IVL | 10061 |
| KRT14 | 9979 |
| KRT33A | 9970 |
| KRT33B | 9839 |
| LIPK | 9746 |
| DSG3 | 9698 |
| KRT75 | 9692 |
| DSC1 | 9667 |
| KRT35 | 9613 |
| KRT13 | 9509 |
| KRT71 | 9470 |
| LCE1B | 9399 |
| LIPJ | 9346 |
| DSG4 | 9214 |
| KRT32 | 9030 |
| KRT23 | 8973 |
| LIPN | 8935 |
| SPINK5 | 8908 |
| CASP14 | 8765 |
| KRT27 | 8637 |
| KRT36 | 8449 |
| KRT6C | 8414 |
| PKP3 | 8407 |
| SPRR2F | 8406 |
| PPL | 8227 |
| SPRR2D | 8090 |
| KRT81 | 8021 |
| KRT26 | 7983 |
| KRT31 | 7716 |
| JUP | 7590 |
| KRT20 | 7244 |
| KRT38 | 7037 |
| LELP1 | 6811 |
| SPRR2G | 6718 |
| KRT7 | 6620 |
| KRT79 | 6556 |
| SPRR2A | 6152 |
| KRT16 | 6020 |
| KRT5 | 5687 |
| KRT73 | 5682 |
| DSG1 | 5521 |
| ST14 | 5446 |
| PCSK6 | 5296 |
| SPRR1A | 5274 |
| LIPM | 5210 |
| TCHH | 4976 |
| KRT77 | 4891 |
| LCE1F | 4759 |
| KRT76 | 4625 |
| LCE3B | 4544 |
| KRT25 | 4352 |
| KRT74 | 4289 |
| PI3 | 4120 |
| LCE2B | 4087 |
| LCE3E | 3969 |
| TGM1 | 3797 |
| LCE4A | 3574 |
| KLK8 | 3510 |
| KLK12 | 2802 |
| FURIN | 2781 |
| LCE2C | 2561 |
| DSP | 1946 |
| CAPN1 | 1603 |
| KRT19 | 1240 |
| PKP1 | 1237 |
| KRT8 | 790 |
| PKP4 | 716 |
| KRT2 | 156 |
| KLK5 | -100 |
| LCE1A | -635 |
| KRT86 | -638 |
| DSG2 | -663 |
| LCE1E | -821 |
| KRT12 | -930 |
| KAZN | -992 |
| EVPL | -1522 |
| LCE2A | -1962 |
| TGM5 | -2211 |
| LCE1C | -2561 |
| KRT72 | -2905 |
| PRSS8 | -3016 |
| CELA2A | -3244 |
| SPRR3 | -3302 |
| KRT9 | -3332 |
| KRT1 | -3356 |
| KRT82 | -3446 |
| KRT78 | -3518 |
| KRT83 | -4838 |
| KRT3 | -4938 |
| CAPNS1 | -5563 |
| PERP | -5957 |
| KRT10 | -6217 |
| LCE5A | -7270 |
| KRT39 | -7450 |
| KLK13 | -7580 |
| KRT34 | -7663 |
| LCE6A | -8100 |
| FLG | -8131 |
| SPINK6 | -8257 |
| KRT6A | -8629 |
| KRT6B | -8791 |
| KRT18 | -8822 |
| CSTA | -8828 |
| KRT40 | -8907 |
| DSC2 | -9070 |
| KRT84 | -9248 |
| RPTN | -9276 |
| DSC3 | -9286 |
| LCE3D | -9386 |
| LCE2D | -9792 |
| PKP2 | -10181 |
| KRT17 | -10723 |
REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES
| 394 | |
|---|---|
| set | REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES |
| setSize | 30 |
| pANOVA | 0.00115 |
| s.dist | 0.343 |
| p.adjustANOVA | 0.377 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CD3D | 11248 |
| LCK | 11167 |
| CD3G | 11103 |
| CD247 | 10977 |
| EVL | 10439 |
| CD3E | 10379 |
| ITK | 10356 |
| ZAP70 | 10155 |
| LAT | 9514 |
| LCP2 | 7144 |
| PAK2 | 7094 |
| ENAH | 6570 |
| HLA-DPB1 | 6054 |
| PLCG1 | 5821 |
| HLA-DPA1 | 5157 |
| GRAP2 | 5061 |
| HLA-DQB2 | 4928 |
| CD101 | 3942 |
| HLA-DRB5 | 3078 |
| HLA-DRB1 | 2099 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CD3D | 11248 |
| LCK | 11167 |
| CD3G | 11103 |
| CD247 | 10977 |
| EVL | 10439 |
| CD3E | 10379 |
| ITK | 10356 |
| ZAP70 | 10155 |
| LAT | 9514 |
| LCP2 | 7144 |
| PAK2 | 7094 |
| ENAH | 6570 |
| HLA-DPB1 | 6054 |
| PLCG1 | 5821 |
| HLA-DPA1 | 5157 |
| GRAP2 | 5061 |
| HLA-DQB2 | 4928 |
| CD101 | 3942 |
| HLA-DRB5 | 3078 |
| HLA-DRB1 | 2099 |
| HLA-DRA | 472 |
| VASP | 322 |
| HLA-DQA2 | -431 |
| PAK1 | -2647 |
| NCK1 | -3078 |
| PLCG2 | -3391 |
| CD4 | -3466 |
| HLA-DQA1 | -4428 |
| HLA-DQB1 | -4567 |
| FYB1 | -9977 |
REACTOME_POU5F1_OCT4_SOX2_NANOG_REPRESS_GENES_RELATED_TO_DIFFERENTIATION
| 525 | |
|---|---|
| set | REACTOME_POU5F1_OCT4_SOX2_NANOG_REPRESS_GENES_RELATED_TO_DIFFERENTIATION |
| setSize | 10 |
| pANOVA | 0.0015 |
| s.dist | -0.58 |
| p.adjustANOVA | 0.412 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| GSC | -10178 |
| NANOG | -9840 |
| CDX2 | -9198 |
| HHEX | -9165 |
| DKK1 | -8178 |
| SOX2 | -5950 |
| TSC22D1 | -5411 |
| GATA6 | -4720 |
| POU5F1 | -3092 |
| EOMES | 4669 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| GSC | -10178 |
| NANOG | -9840 |
| CDX2 | -9198 |
| HHEX | -9165 |
| DKK1 | -8178 |
| SOX2 | -5950 |
| TSC22D1 | -5411 |
| GATA6 | -4720 |
| POU5F1 | -3092 |
| EOMES | 4669 |
REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH
| 600 | |
|---|---|
| set | REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH |
| setSize | 62 |
| pANOVA | 0.00179 |
| s.dist | 0.229 |
| p.adjustANOVA | 0.421 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| COL3A1 | 10666 |
| SPTBN5 | 10403 |
| HRAS | 10358 |
| COL5A2 | 10298 |
| COL9A3 | 10012 |
| MAPK3 | 9611 |
| GFRA4 | 9589 |
| FGFR1 | 9377 |
| COL5A1 | 8607 |
| CACNA1S | 8329 |
| PSPN | 7756 |
| COL6A6 | 7452 |
| CACNA1G | 7425 |
| SRC | 7174 |
| CACNA1I | 7155 |
| SPTBN2 | 7113 |
| COL4A3 | 6632 |
| GRB2 | 6547 |
| NRTN | 6334 |
| PTK2 | 6033 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| COL3A1 | 10666 |
| SPTBN5 | 10403 |
| HRAS | 10358 |
| COL5A2 | 10298 |
| COL9A3 | 10012 |
| MAPK3 | 9611 |
| GFRA4 | 9589 |
| FGFR1 | 9377 |
| COL5A1 | 8607 |
| CACNA1S | 8329 |
| PSPN | 7756 |
| COL6A6 | 7452 |
| CACNA1G | 7425 |
| SRC | 7174 |
| CACNA1I | 7155 |
| SPTBN2 | 7113 |
| COL4A3 | 6632 |
| GRB2 | 6547 |
| NRTN | 6334 |
| PTK2 | 6033 |
| NCAN | 5727 |
| SPTB | 5570 |
| MAPK1 | 5363 |
| COL6A3 | 4444 |
| NRAS | 4302 |
| AGRN | 4176 |
| CREB1 | 4166 |
| CACNA1D | 4069 |
| COL6A2 | 3880 |
| CACNA1C | 3830 |
| CNTN2 | 3485 |
| FYN | 3400 |
| GFRA2 | 3375 |
| CACNB3 | 2990 |
| COL6A5 | 2908 |
| COL2A1 | 2874 |
| CACNB4 | 2684 |
| PTPRA | 1826 |
| SPTAN1 | 1620 |
| PRNP | 1423 |
| COL9A1 | 1381 |
| COL4A4 | 1128 |
| COL6A1 | 1016 |
| ST8SIA2 | 962 |
| CACNA1H | 930 |
| SPTBN1 | 782 |
| SOS1 | 754 |
| CACNB1 | 129 |
| COL9A2 | 82 |
| CACNB2 | -1006 |
| COL4A2 | -2079 |
| ST8SIA4 | -2885 |
| SPTA1 | -3093 |
| SPTBN4 | -3936 |
| COL4A1 | -4406 |
| RPS6KA5 | -5721 |
| GFRA1 | -6358 |
| NCAM1 | -7555 |
| KRAS | -8414 |
| COL5A3 | -8652 |
| GDNF | -9268 |
| ARTN | -10193 |
REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY
| 635 | |
|---|---|
| set | REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY |
| setSize | 64 |
| pANOVA | 0.00245 |
| s.dist | 0.219 |
| p.adjustANOVA | 0.477 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CD3D | 11248 |
| LCK | 11167 |
| PDCD1 | 11137 |
| CD3G | 11103 |
| CD247 | 10977 |
| CSK | 10837 |
| CD28 | 10736 |
| BTLA | 10645 |
| CD80 | 10546 |
| CD3E | 10379 |
| PIK3CA | 7340 |
| PPP2R5C | 7231 |
| SRC | 7174 |
| PAK2 | 7094 |
| PDPK1 | 6912 |
| PIK3R2 | 6728 |
| GRB2 | 6547 |
| AKT3 | 6314 |
| HLA-DPB1 | 6054 |
| PPP2R5A | 5524 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CD3D | 11248 |
| LCK | 11167 |
| PDCD1 | 11137 |
| CD3G | 11103 |
| CD247 | 10977 |
| CSK | 10837 |
| CD28 | 10736 |
| BTLA | 10645 |
| CD80 | 10546 |
| CD3E | 10379 |
| PIK3CA | 7340 |
| PPP2R5C | 7231 |
| SRC | 7174 |
| PAK2 | 7094 |
| PDPK1 | 6912 |
| PIK3R2 | 6728 |
| GRB2 | 6547 |
| AKT3 | 6314 |
| HLA-DPB1 | 6054 |
| PPP2R5A | 5524 |
| CTLA4 | 5310 |
| HLA-DPA1 | 5157 |
| AKT2 | 5123 |
| GRAP2 | 5061 |
| HLA-DQB2 | 4928 |
| AKT1 | 4665 |
| VAV1 | 4284 |
| CD274 | 4090 |
| FYN | 3400 |
| MTOR | 3115 |
| HLA-DRB5 | 3078 |
| PPP2R1B | 2712 |
| PPP2R5D | 2594 |
| PPP2R5E | 2184 |
| HLA-DRB1 | 2099 |
| PTPN11 | 936 |
| LYN | 889 |
| TRIB3 | 769 |
| PPP2CA | 766 |
| PPP2CB | 630 |
| HLA-DRA | 472 |
| MAPKAP1 | 436 |
| PDCD1LG2 | 334 |
| THEM4 | 170 |
| PIK3R3 | 32 |
| ICOS | -52 |
| RAC1 | -259 |
| HLA-DQA2 | -431 |
| RICTOR | -1129 |
| YES1 | -1376 |
| CDC42 | -1417 |
| MAP3K8 | -2439 |
| PAK1 | -2647 |
| PPP2R1A | -2855 |
| CD4 | -3466 |
| PTPN6 | -4209 |
| HLA-DQA1 | -4428 |
| HLA-DQB1 | -4567 |
| PRR5 | -4797 |
| CD86 | -4872 |
| MAP3K14 | -5301 |
| PPP2R5B | -7629 |
| PIK3R1 | -7787 |
| MLST8 | -8382 |
REACTOME_TYPE_I_HEMIDESMOSOME_ASSEMBLY
| 783 | |
|---|---|
| set | REACTOME_TYPE_I_HEMIDESMOSOME_ASSEMBLY |
| setSize | 11 |
| pANOVA | 0.00261 |
| s.dist | 0.524 |
| p.adjustANOVA | 0.477 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| KRT14 | 9979 |
| LAMB3 | 8773 |
| CD151 | 7929 |
| PLEC | 7470 |
| ITGA6 | 7143 |
| COL17A1 | 6567 |
| LAMA3 | 6082 |
| KRT5 | 5687 |
| ITGB4 | 4242 |
| LAMC2 | 1741 |
| DST | 737 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| KRT14 | 9979 |
| LAMB3 | 8773 |
| CD151 | 7929 |
| PLEC | 7470 |
| ITGA6 | 7143 |
| COL17A1 | 6567 |
| LAMA3 | 6082 |
| KRT5 | 5687 |
| ITGB4 | 4242 |
| LAMC2 | 1741 |
| DST | 737 |
REACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS
| 837 | |
|---|---|
| set | REACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS |
| setSize | 16 |
| pANOVA | 0.00354 |
| s.dist | 0.421 |
| p.adjustANOVA | 0.581 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| MUC20 | 10878 |
| MUC1 | 10023 |
| MUC4 | 9620 |
| MUC5B | 9326 |
| MUC6 | 8308 |
| MUC12 | 7326 |
| MUC15 | 7042 |
| MUC13 | 6580 |
| MUC7 | 6252 |
| MUC5AC | 3970 |
| MUC3A | 3746 |
| MUC16 | 3658 |
| MUC21 | 1269 |
| MUC17 | 238 |
| C1GALT1 | -976 |
| MUCL1 | -8884 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MUC20 | 10878 |
| MUC1 | 10023 |
| MUC4 | 9620 |
| MUC5B | 9326 |
| MUC6 | 8308 |
| MUC12 | 7326 |
| MUC15 | 7042 |
| MUC13 | 6580 |
| MUC7 | 6252 |
| MUC5AC | 3970 |
| MUC3A | 3746 |
| MUC16 | 3658 |
| MUC21 | 1269 |
| MUC17 | 238 |
| C1GALT1 | -976 |
| MUCL1 | -8884 |
REACTOME_TCR_SIGNALING
| 391 | |
|---|---|
| set | REACTOME_TCR_SIGNALING |
| setSize | 113 |
| pANOVA | 0.0049 |
| s.dist | 0.153 |
| p.adjustANOVA | 0.715 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CD3D | 11248 |
| LCK | 11167 |
| CD3G | 11103 |
| CD247 | 10977 |
| CSK | 10837 |
| EVL | 10439 |
| CD3E | 10379 |
| ITK | 10356 |
| UBE2V1 | 10263 |
| ZAP70 | 10155 |
| LAT | 9514 |
| PSMB11 | 9358 |
| PSME1 | 9064 |
| PSMC6 | 8742 |
| TRAT1 | 8635 |
| PSMC4 | 8618 |
| PSMB10 | 8440 |
| PTPRC | 8415 |
| PSMD9 | 7540 |
| PIK3CA | 7340 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CD3D | 11248 |
| LCK | 11167 |
| CD3G | 11103 |
| CD247 | 10977 |
| CSK | 10837 |
| EVL | 10439 |
| CD3E | 10379 |
| ITK | 10356 |
| UBE2V1 | 10263 |
| ZAP70 | 10155 |
| LAT | 9514 |
| PSMB11 | 9358 |
| PSME1 | 9064 |
| PSMC6 | 8742 |
| TRAT1 | 8635 |
| PSMC4 | 8618 |
| PSMB10 | 8440 |
| PTPRC | 8415 |
| PSMD9 | 7540 |
| PIK3CA | 7340 |
| LCP2 | 7144 |
| PAK2 | 7094 |
| PDPK1 | 6912 |
| PSMD2 | 6891 |
| UBE2D2 | 6730 |
| PIK3R2 | 6728 |
| ENAH | 6570 |
| PSMB5 | 6566 |
| PSMD13 | 6561 |
| UBC | 6258 |
| HLA-DPB1 | 6054 |
| PSME2 | 5834 |
| PRKCQ | 5824 |
| PLCG1 | 5821 |
| CDC34 | 5788 |
| PSMC3 | 5595 |
| INPP5D | 5534 |
| PAG1 | 5496 |
| HLA-DPA1 | 5157 |
| GRAP2 | 5061 |
| PSMB4 | 4961 |
| HLA-DQB2 | 4928 |
| PSMD12 | 4000 |
| CD101 | 3942 |
| PSMB6 | 3841 |
| UBE2D1 | 3769 |
| IKBKB | 3671 |
| CARD11 | 3447 |
| PSMD11 | 3372 |
| RIPK2 | 3191 |
| HLA-DRB5 | 3078 |
| PTEN | 2986 |
| UBB | 2521 |
| PSMA3 | 2388 |
| PSMD6 | 2217 |
| NFKBIA | 2178 |
| SKP1 | 2115 |
| HLA-DRB1 | 2099 |
| PSMD3 | 1999 |
| PSMA6 | 1940 |
| PSME3 | 1671 |
| BTRC | 965 |
| SEM1 | 725 |
| PIK3CB | 564 |
| PSMD5 | 562 |
| HLA-DRA | 472 |
| PSMC5 | 416 |
| VASP | 322 |
| PSMA7 | -126 |
| NFKB1 | -235 |
| TRAF6 | -307 |
| PSMF1 | -417 |
| HLA-DQA2 | -431 |
| PSMD1 | -503 |
| RPS27A | -595 |
| PSMD7 | -880 |
| PSMC1 | -885 |
| RELA | -1401 |
| PSMD8 | -1553 |
| PSMA1 | -1674 |
| PSMB8 | -1750 |
| PSMA8 | -1797 |
| MAP3K7 | -1908 |
| FBXW11 | -2380 |
| PAK1 | -2647 |
| UBA52 | -2703 |
| PSMB9 | -2790 |
| PSMA2 | -2839 |
| PSMA5 | -2988 |
| NCK1 | -3078 |
| PSMA4 | -3236 |
| PLCG2 | -3391 |
| CD4 | -3466 |
| PSMD14 | -3626 |
| PSMB2 | -3722 |
| PSMB1 | -3823 |
| PSMD4 | -3996 |
| CHUK | -4107 |
| HLA-DQA1 | -4428 |
| HLA-DQB1 | -4567 |
| UBE2N | -4635 |
| TAB2 | -5165 |
| PSMC2 | -5276 |
| MALT1 | -6153 |
| PTPN22 | -6350 |
| CUL1 | -6713 |
| PSMB3 | -6733 |
| PSME4 | -7401 |
| PIK3R1 | -7787 |
| BCL10 | -7934 |
| PTPRJ | -8915 |
| PSMB7 | -9461 |
| FYB1 | -9977 |
REACTOME_PD_1_SIGNALING
| 646 | |
|---|---|
| set | REACTOME_PD_1_SIGNALING |
| setSize | 21 |
| pANOVA | 0.00522 |
| s.dist | 0.352 |
| p.adjustANOVA | 0.715 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CD3D | 11248 |
| LCK | 11167 |
| PDCD1 | 11137 |
| CD3G | 11103 |
| CD247 | 10977 |
| CSK | 10837 |
| CD3E | 10379 |
| HLA-DPB1 | 6054 |
| HLA-DPA1 | 5157 |
| HLA-DQB2 | 4928 |
| CD274 | 4090 |
| HLA-DRB5 | 3078 |
| HLA-DRB1 | 2099 |
| PTPN11 | 936 |
| HLA-DRA | 472 |
| PDCD1LG2 | 334 |
| HLA-DQA2 | -431 |
| CD4 | -3466 |
| PTPN6 | -4209 |
| HLA-DQA1 | -4428 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CD3D | 11248 |
| LCK | 11167 |
| PDCD1 | 11137 |
| CD3G | 11103 |
| CD247 | 10977 |
| CSK | 10837 |
| CD3E | 10379 |
| HLA-DPB1 | 6054 |
| HLA-DPA1 | 5157 |
| HLA-DQB2 | 4928 |
| CD274 | 4090 |
| HLA-DRB5 | 3078 |
| HLA-DRB1 | 2099 |
| PTPN11 | 936 |
| HLA-DRA | 472 |
| PDCD1LG2 | 334 |
| HLA-DQA2 | -431 |
| CD4 | -3466 |
| PTPN6 | -4209 |
| HLA-DQA1 | -4428 |
| HLA-DQB1 | -4567 |
REACTOME_VISUAL_PHOTOTRANSDUCTION
| 473 | |
|---|---|
| set | REACTOME_VISUAL_PHOTOTRANSDUCTION |
| setSize | 93 |
| pANOVA | 0.00713 |
| s.dist | 0.161 |
| p.adjustANOVA | 0.775 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| AKR1B10 | 10915 |
| PDE6G | 10653 |
| RPE65 | 10551 |
| APOB | 10547 |
| APOA4 | 10458 |
| STRA6 | 10262 |
| RDH5 | 10229 |
| LRP10 | 10152 |
| AKR1C1 | 10063 |
| SDR9C7 | 9771 |
| APOM | 9496 |
| RBP3 | 9474 |
| RLBP1 | 9191 |
| GRK4 | 8423 |
| PLB1 | 8258 |
| GPC1 | 8168 |
| HSD17B1 | 7899 |
| APOC3 | 7217 |
| LRP1 | 7098 |
| SLC24A1 | 6763 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| AKR1B10 | 10915 |
| PDE6G | 10653 |
| RPE65 | 10551 |
| APOB | 10547 |
| APOA4 | 10458 |
| STRA6 | 10262 |
| RDH5 | 10229 |
| LRP10 | 10152 |
| AKR1C1 | 10063 |
| SDR9C7 | 9771 |
| APOM | 9496 |
| RBP3 | 9474 |
| RLBP1 | 9191 |
| GRK4 | 8423 |
| PLB1 | 8258 |
| GPC1 | 8168 |
| HSD17B1 | 7899 |
| APOC3 | 7217 |
| LRP1 | 7098 |
| SLC24A1 | 6763 |
| METAP2 | 6746 |
| GPIHBP1 | 6629 |
| APOA1 | 6606 |
| SDC4 | 6457 |
| BCO2 | 6257 |
| NMT2 | 6134 |
| APOE | 5919 |
| PRKCQ | 5824 |
| FNTB | 5549 |
| DHRS3 | 5393 |
| AKR1C4 | 5346 |
| GPC2 | 5173 |
| MYO7A | 5070 |
| GNGT1 | 4980 |
| FNTA | 4900 |
| GRK7 | 4863 |
| RDH8 | 4636 |
| PDE6B | 4547 |
| AGRN | 4176 |
| GUCA1B | 3906 |
| RBP1 | 3872 |
| CLPS | 3744 |
| NAPEPLD | 3481 |
| GPC6 | 3392 |
| NMT1 | 3380 |
| GUCA1A | 3341 |
| RDH16 | 3096 |
| RGS9 | 2692 |
| GUCY2D | 2458 |
| CNGA1 | 2432 |
| LRP12 | 2412 |
| RBP2 | 2362 |
| RDH11 | 2328 |
| RDH10 | 2246 |
| GRK1 | 2182 |
| METAP1 | 1655 |
| CYP4V2 | 1466 |
| GUCA1C | 1049 |
| HSPG2 | 836 |
| CAMKMT | 724 |
| GPC5 | 638 |
| RCVRN | 335 |
| GNAT1 | 222 |
| CALM1 | 217 |
| SDC2 | 192 |
| SDC1 | -681 |
| ABCA4 | -1631 |
| PRKCA | -1711 |
| CNGB1 | -1808 |
| RDH12 | -1965 |
| LRP2 | -2055 |
| TTR | -2303 |
| RHO | -3541 |
| RGS9BP | -3765 |
| LDLR | -3968 |
| HSD17B6 | -4227 |
| GNB5 | -4404 |
| AKR1C3 | -4506 |
| LRP8 | -4680 |
| RETSAT | -5596 |
| LRAT | -5759 |
| DHRS9 | -6204 |
| SDC3 | -6333 |
| GNB1 | -7076 |
| LPL | -7517 |
| SAG | -8787 |
| OPN1SW | -9062 |
| PDE6A | -9328 |
| PNLIP | -9433 |
| RBP4 | -9438 |
| APOC2 | -9853 |
| BCO1 | -9962 |
| APOA2 | -10439 |
REACTOME_GLUCOCORTICOID_BIOSYNTHESIS
| 337 | |
|---|---|
| set | REACTOME_GLUCOCORTICOID_BIOSYNTHESIS |
| setSize | 10 |
| pANOVA | 0.00724 |
| s.dist | 0.49 |
| p.adjustANOVA | 0.775 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CYP21A2 | 11147 |
| HSD3B2 | 10055 |
| CYP11B1 | 9186 |
| CYP11B2 | 8558 |
| HSD3B1 | 7845 |
| POMC | 6829 |
| CYP17A1 | 6789 |
| HSD11B2 | 1787 |
| SERPINA6 | 913 |
| HSD11B1 | -6489 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CYP21A2 | 11147 |
| HSD3B2 | 10055 |
| CYP11B1 | 9186 |
| CYP11B2 | 8558 |
| HSD3B1 | 7845 |
| POMC | 6829 |
| CYP17A1 | 6789 |
| HSD11B2 | 1787 |
| SERPINA6 | 913 |
| HSD11B1 | -6489 |
REACTOME_DETOXIFICATION_OF_REACTIVE_OXYGEN_SPECIES
| 563 | |
|---|---|
| set | REACTOME_DETOXIFICATION_OF_REACTIVE_OXYGEN_SPECIES |
| setSize | 34 |
| pANOVA | 0.00752 |
| s.dist | -0.265 |
| p.adjustANOVA | 0.775 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| GPX8 | -9982 |
| GSTP1 | -9813 |
| P4HB | -9616 |
| NCF2 | -9561 |
| SOD3 | -9090 |
| CAT | -9061 |
| NOX4 | -9046 |
| GSR | -8877 |
| SOD2 | -8491 |
| PRDX3 | -7000 |
| PRDX2 | -6753 |
| GPX7 | -6569 |
| GPX3 | -5841 |
| NCF4 | -5286 |
| CCS | -5203 |
| PRDX5 | -4258 |
| AQP8 | -3982 |
| GPX2 | -3871 |
| GPX5 | -2942 |
| SOD1 | -2661 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| GPX8 | -9982 |
| GSTP1 | -9813 |
| P4HB | -9616 |
| NCF2 | -9561 |
| SOD3 | -9090 |
| CAT | -9061 |
| NOX4 | -9046 |
| GSR | -8877 |
| SOD2 | -8491 |
| PRDX3 | -7000 |
| PRDX2 | -6753 |
| GPX7 | -6569 |
| GPX3 | -5841 |
| NCF4 | -5286 |
| CCS | -5203 |
| PRDX5 | -4258 |
| AQP8 | -3982 |
| GPX2 | -3871 |
| GPX5 | -2942 |
| SOD1 | -2661 |
| GPX1 | -2002 |
| PRDX1 | -1638 |
| TXNRD1 | -396 |
| ATOX1 | 876 |
| GPX6 | 2626 |
| ERO1A | 3090 |
| TXN | 3298 |
| TXN2 | 3344 |
| PRDX6 | 4363 |
| NUDT2 | 4779 |
| CYCS | 5295 |
| TXNRD2 | 7524 |
| NOX5 | 7554 |
| CYBA | 9369 |
REACTOME_CARNITINE_METABOLISM
| 376 | |
|---|---|
| set | REACTOME_CARNITINE_METABOLISM |
| setSize | 13 |
| pANOVA | 0.00775 |
| s.dist | -0.426 |
| p.adjustANOVA | 0.775 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CPT2 | -9943 |
| THRSP | -9814 |
| CPT1B | -9709 |
| PRKAA2 | -9031 |
| ACACA | -7665 |
| ACACB | -6537 |
| SLC22A5 | -6317 |
| PRKAB2 | -4965 |
| PRKAG2 | -4451 |
| CPT1A | -489 |
| RXRA | 950 |
| PPARD | 4014 |
| SLC25A20 | 6471 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CPT2 | -9943 |
| THRSP | -9814 |
| CPT1B | -9709 |
| PRKAA2 | -9031 |
| ACACA | -7665 |
| ACACB | -6537 |
| SLC22A5 | -6317 |
| PRKAB2 | -4965 |
| PRKAG2 | -4451 |
| CPT1A | -489 |
| RXRA | 950 |
| PPARD | 4014 |
| SLC25A20 | 6471 |
REACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC
| 835 | |
|---|---|
| set | REACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC |
| setSize | 16 |
| pANOVA | 0.00805 |
| s.dist | 0.383 |
| p.adjustANOVA | 0.775 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| MUC20 | 10878 |
| MUC1 | 10023 |
| MUC4 | 9620 |
| MUC5B | 9326 |
| MUC6 | 8308 |
| MUC12 | 7326 |
| MUC15 | 7042 |
| MUC13 | 6580 |
| MUC7 | 6252 |
| MUC5AC | 3970 |
| MUC3A | 3746 |
| MUC16 | 3658 |
| MUC21 | 1269 |
| MUC17 | 238 |
| GALNT3 | -7751 |
| MUCL1 | -8884 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MUC20 | 10878 |
| MUC1 | 10023 |
| MUC4 | 9620 |
| MUC5B | 9326 |
| MUC6 | 8308 |
| MUC12 | 7326 |
| MUC15 | 7042 |
| MUC13 | 6580 |
| MUC7 | 6252 |
| MUC5AC | 3970 |
| MUC3A | 3746 |
| MUC16 | 3658 |
| MUC21 | 1269 |
| MUC17 | 238 |
| GALNT3 | -7751 |
| MUCL1 | -8884 |
REACTOME_OLFACTORY_SIGNALING_PATHWAY
| 628 | |
|---|---|
| set | REACTOME_OLFACTORY_SIGNALING_PATHWAY |
| setSize | 348 |
| pANOVA | 0.00867 |
| s.dist | 0.0819 |
| p.adjustANOVA | 0.775 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| OR10H2 | 11246 |
| OR52E6 | 11236 |
| OR51V1 | 11185 |
| OR2T3 | 11166 |
| OR7D4 | 11139 |
| OR7A10 | 11125 |
| OR56B4 | 11111 |
| OR5M3 | 11094 |
| OR5T2 | 11049 |
| OR52H1 | 11042 |
| OR2AK2 | 10946 |
| OR10Z1 | 10899 |
| OR2T33 | 10894 |
| OR13G1 | 10850 |
| OR4A5 | 10821 |
| OR52N1 | 10820 |
| OR2V1 | 10802 |
| OR13J1 | 10797 |
| OR10H5 | 10795 |
| OR6B2 | 10784 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| OR10H2 | 11246.0 |
| OR52E6 | 11236.0 |
| OR51V1 | 11185.0 |
| OR2T3 | 11166.0 |
| OR7D4 | 11139.0 |
| OR7A10 | 11125.0 |
| OR56B4 | 11111.0 |
| OR5M3 | 11094.0 |
| OR5T2 | 11049.0 |
| OR52H1 | 11042.0 |
| OR2AK2 | 10946.0 |
| OR10Z1 | 10899.0 |
| OR2T33 | 10894.0 |
| OR13G1 | 10850.0 |
| OR4A5 | 10821.0 |
| OR52N1 | 10820.0 |
| OR2V1 | 10802.0 |
| OR13J1 | 10797.0 |
| OR10H5 | 10795.0 |
| OR6B2 | 10784.0 |
| OR2H2 | 10771.0 |
| OR52E2 | 10714.0 |
| OR2L2 | 10708.0 |
| OR6N2 | 10696.0 |
| OR4N2 | 10669.0 |
| OR6C65 | 10662.0 |
| OR10G2 | 10650.0 |
| OR6C6 | 10588.0 |
| OR2A2 | 10488.0 |
| OR6K3 | 10483.0 |
| OR5K4 | 10456.0 |
| OR2T27 | 10418.0 |
| OR4D10 | 10413.0 |
| OR2Y1 | 10389.0 |
| OR14C36 | 10375.0 |
| OR52A5 | 10353.0 |
| OR1A2 | 10325.0 |
| OR52K1 | 10280.0 |
| OR4D6 | 10276.0 |
| OR1E1 | 10200.0 |
| OR10A6 | 10172.0 |
| OR2T12 | 10171.0 |
| OR2M3 | 10140.0 |
| OR5D13 | 10099.0 |
| OR4B1 | 10088.0 |
| OR6C74 | 10073.0 |
| OR2G6 | 10059.0 |
| OR11G2 | 10037.0 |
| RTP1 | 10025.0 |
| OR52A1 | 9995.0 |
| OR10G3 | 9977.0 |
| OR10K2 | 9862.0 |
| OR2L3 | 9847.0 |
| OR5T3 | 9792.0 |
| OR6C1 | 9726.0 |
| OR2D3 | 9717.0 |
| OR10G9 | 9614.0 |
| OR6C3 | 9573.0 |
| OR1J4 | 9566.0 |
| OR5AR1 | 9551.0 |
| OR10H4 | 9549.0 |
| OR11H6 | 9532.0 |
| OR51F2 | 9516.0 |
| OR6C2 | 9443.0 |
| OR1N1 | 9402.0 |
| OR2A14 | 9374.0 |
| OR51Q1 | 9325.0 |
| OR4K5 | 9304.0 |
| OR2K2 | 9301.0 |
| OR6C4 | 9274.0 |
| OR5K2 | 9223.0 |
| OR1A1 | 9196.0 |
| OR2T8 | 9185.0 |
| OR6F1 | 9178.0 |
| OR5J2 | 9124.0 |
| OR4K2 | 9084.0 |
| OR51B2 | 9075.0 |
| REEP1 | 9073.0 |
| OR4N5 | 9046.0 |
| OR2F2 | 9013.0 |
| OR6N1 | 8970.0 |
| OR9Q2 | 8960.0 |
| OR6C68 | 8943.0 |
| OR5A2 | 8919.0 |
| OR10AD1 | 8810.0 |
| OR13C9 | 8774.0 |
| OR4C3 | 8726.0 |
| OR5AN1 | 8701.0 |
| OR2T6 | 8685.0 |
| OR52M1 | 8669.0 |
| OR52W1 | 8662.0 |
| OR10X1 | 8644.0 |
| OR2H1 | 8577.0 |
| OR9G4 | 8541.0 |
| OR8U1 | 8527.0 |
| OR9A2 | 8523.0 |
| OR14J1 | 8502.0 |
| OR7C1 | 8485.0 |
| OR9Q1 | 8400.0 |
| OR8J1 | 8290.0 |
| OR5L1 | 8281.0 |
| OR10S1 | 8128.0 |
| OR6Q1 | 8006.0 |
| GNG13 | 7984.0 |
| OR10T2 | 7849.0 |
| OR51B5 | 7847.0 |
| OR14I1 | 7829.0 |
| OR3A3 | 7560.0 |
| OR6B1 | 7463.0 |
| OR10K1 | 7382.0 |
| OR10H1 | 7375.0 |
| OR1B1 | 7350.0 |
| OR2F1 | 7280.0 |
| OR1G1 | 7207.0 |
| OR5F1 | 7052.0 |
| OR4X1 | 6845.0 |
| OR56A4 | 6835.0 |
| OR51G2 | 6653.0 |
| OR11H4 | 6591.0 |
| OR4K14 | 6532.0 |
| OR9K2 | 6511.0 |
| LDB1 | 6482.0 |
| OR1C1 | 6480.0 |
| OR52I1 | 6441.0 |
| OR2T4 | 6388.0 |
| OR2L5 | 6371.0 |
| OR5AU1 | 6365.0 |
| OR10A2 | 6305.0 |
| OR2Z1 | 6231.0 |
| OR4C15 | 5934.0 |
| OR5H6 | 5684.0 |
| OR5H15 | 5674.0 |
| OR5H1 | 5591.0 |
| OR5W2 | 5531.0 |
| OR7C2 | 5301.0 |
| OR8I2 | 5263.0 |
| OR5H2 | 5253.0 |
| OR2L13 | 5249.0 |
| OR8B12 | 5185.0 |
| OR5T1 | 5108.0 |
| OR10J1 | 5043.0 |
| OR8G1 | 4986.0 |
| OR5D18 | 4952.0 |
| OR8K5 | 4889.0 |
| OR1L8 | 4850.0 |
| OR10V1 | 4840.0 |
| RTP2 | 4785.0 |
| OR2J2 | 4717.0 |
| OR2C3 | 4711.0 |
| OR1L6 | 4709.0 |
| OR51S1 | 4684.0 |
| OR1F1 | 4664.0 |
| OR7G2 | 4489.0 |
| OR10W1 | 4472.0 |
| OR4K17 | 4297.0 |
| OR8J3 | 4065.0 |
| OR4S1 | 4016.0 |
| OR2G3 | 3780.0 |
| OR1D2 | 3714.0 |
| OR11A1 | 3674.0 |
| OR4F15 | 3434.0 |
| OR2M2 | 3407.0 |
| OR52E8 | 3239.0 |
| OR2AG1 | 3172.0 |
| OR10A5 | 3151.0 |
| OR13C4 | 3148.0 |
| OR6K6 | 3144.0 |
| OR52D1 | 3094.0 |
| EBF1 | 2954.0 |
| OR56A3 | 2875.0 |
| OR7A17 | 2839.0 |
| OR2W1 | 2799.0 |
| OR2C1 | 2524.0 |
| OR4D5 | 2335.0 |
| OR10A4 | 2321.0 |
| OR7D2 | 2302.0 |
| OR6B3 | 2301.0 |
| OR5L2 | 2210.0 |
| OR1I1 | 2161.0 |
| OR2AP1 | 2117.0 |
| OR2B3 | 2040.0 |
| OR8K3 | 1942.0 |
| OR5C1 | 1926.0 |
| OR2AG2 | 1782.0 |
| OR4C12 | 1736.0 |
| OR12D3 | 1623.0 |
| OR2AE1 | 1528.0 |
| OR5AP2 | 1488.0 |
| OR8D4 | 1388.0 |
| OR5B3 | 1364.0 |
| OR13C3 | 1334.0 |
| OR6M1 | 1103.0 |
| OR7G1 | 834.0 |
| OR10A7 | 828.0 |
| OR13A1 | 825.0 |
| OR2AT4 | 500.0 |
| OR5D14 | 102.0 |
| OR2G2 | -39.0 |
| OR4K15 | -415.0 |
| OR5K1 | -420.0 |
| OR13F1 | -599.0 |
| OR13C2 | -720.0 |
| OR1N2 | -739.0 |
| OR1J2 | -788.0 |
| OR6Y1 | -955.0 |
| ANO2 | -1050.0 |
| OR10J5 | -1366.0 |
| OR1E2 | -1490.0 |
| OR5V1 | -1589.0 |
| OR4A47 | -1666.0 |
| OR4L1 | -1776.0 |
| OR6C76 | -1782.0 |
| CNGB1 | -1808.0 |
| OR4M1 | -1821.0 |
| OR51L1 | -1987.0 |
| OR51E1 | -1997.0 |
| OR5A1 | -2312.0 |
| GNAL | -2635.0 |
| OR51A7 | -2889.0 |
| OR10J3 | -2963.0 |
| OR5M9 | -3068.0 |
| OR7E24 | -3132.0 |
| OR2L8 | -3230.0 |
| OR4D11 | -3324.0 |
| OR8G5 | -3741.0 |
| OR4A16 | -3750.0 |
| OR4C45 | -3867.0 |
| OR4F6 | -3885.0 |
| OR2S2 | -4202.0 |
| OR5D16 | -4292.0 |
| OR2B11 | -4322.0 |
| OR4X2 | -4374.0 |
| OR8D2 | -4423.0 |
| OR9I1 | -4437.0 |
| OR8K1 | -4560.0 |
| OR52B2 | -4613.0 |
| OR10A3 | -4733.0 |
| OR8U8 | -5077.0 |
| OR52J3 | -5144.0 |
| OR51B6 | -5214.0 |
| ADCY3 | -5265.0 |
| OR1K1 | -5333.0 |
| OR51M1 | -5371.0 |
| OR10Q1 | -5397.0 |
| OR52R1 | -5413.0 |
| OR1Q1 | -5428.0 |
| OR1L4 | -5567.0 |
| OR6K2 | -5586.0 |
| OR4D2 | -5589.0 |
| OR6X1 | -5696.0 |
| OR6C70 | -5859.0 |
| OR5AK2 | -5862.0 |
| OR7A5 | -5924.0 |
| OR4C6 | -6045.0 |
| OR1M1 | -6157.0 |
| OR3A2 | -6203.0 |
| OR1L3 | -6236.0 |
| OR12D2 | -6274.0 |
| OR8B2 | -6279.0 |
| OR51E2 | -6372.0 |
| OR2M4 | -6378.0 |
| OR2A12 | -6396.0 |
| OR5B12 | -6584.0 |
| OR6T1 | -6646.0 |
| OR3A1 | -6657.0 |
| OR10G8 | -6668.0 |
| OR1S1 | -6810.0 |
| OR2V2 | -6879.0 |
| LHX2 | -6967.0 |
| GNB1 | -7076.0 |
| OR2D2 | -7210.0 |
| OR8S1 | -7226.0 |
| OR4A15 | -7238.0 |
| OR4E2 | -7320.0 |
| OR51I1 | -7373.0 |
| OR8H3 | -7381.0 |
| CNGA4 | -7411.0 |
| OR52B6 | -7446.0 |
| OR5M10 | -7482.0 |
| OR8H1 | -7551.0 |
| OR5M1 | -7641.0 |
| OR2W3 | -7692.0 |
| OR8U3 | -7776.0 |
| OR51G1 | -7883.0 |
| OR4K1 | -8024.0 |
| OR51A2 | -8162.0 |
| OR2T1 | -8234.0 |
| OR10H3 | -8309.0 |
| OR51B4 | -8333.0 |
| OR13C8 | -8383.0 |
| OR10P1 | -8580.0 |
| OR6A2 | -8731.0 |
| OR4D1 | -8739.0 |
| OR51D1 | -8767.0 |
| OR52E4 | -8797.0 |
| OR51I2 | -8864.0 |
| OR5M11 | -8910.0 |
| OR6V1 | -9060.0 |
| OR5AS1 | -9091.0 |
| OR52I2 | -9134.0 |
| OR2M7 | -9150.0 |
| OR52N2 | -9162.0 |
| OR9G1 | -9178.5 |
| OR9G9 | -9178.5 |
| OR6S1 | -9206.0 |
| OR1L1 | -9209.0 |
| OR10G4 | -9217.0 |
| OR2T11 | -9379.0 |
| OR5AC2 | -9384.0 |
| OR5P3 | -9385.0 |
| OR56A1 | -9414.0 |
| OR5B2 | -9439.0 |
| OR10AG1 | -9490.0 |
| OR5I1 | -9502.0 |
| OR13D1 | -9618.0 |
| OR2M5 | -9635.0 |
| OR9A4 | -9675.0 |
| OR11L1 | -9679.0 |
| OR6C75 | -9683.0 |
| OR8B4 | -9684.0 |
| OR5B21 | -9732.0 |
| OR2B6 | -9796.0 |
| OR8B8 | -9901.0 |
| OR10C1 | -9928.0 |
| OR2A5 | -9949.0 |
| OR5M8 | -10047.0 |
| OR1J1 | -10060.0 |
| OR4C16 | -10090.0 |
| OR4K13 | -10095.0 |
| OR8D1 | -10121.0 |
| OR51T1 | -10167.0 |
| OR6P1 | -10210.0 |
| OR4D9 | -10240.0 |
| OR1S2 | -10252.0 |
| OR7G3 | -10271.0 |
| OR56B1 | -10284.0 |
| OR14A16 | -10326.0 |
| OR52K2 | -10327.0 |
| OR5P2 | -10358.0 |
| OR8A1 | -10410.0 |
| OR5K3 | -10412.0 |
| OR2B2 | -10413.0 |
| OR52L1 | -10507.0 |
| OR5B17 | -10538.0 |
| OR10G7 | -10545.0 |
| OR56A5 | -10561.0 |
| OR4C46 | -10677.0 |
| OR51F1 | -10727.0 |
REACTOME_P75NTR_REGULATES_AXONOGENESIS
| 332 | |
|---|---|
| set | REACTOME_P75NTR_REGULATES_AXONOGENESIS |
| setSize | 9 |
| pANOVA | 0.00936 |
| s.dist | 0.5 |
| p.adjustANOVA | 0.775 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RTN4R | 10240 |
| MAG | 10080 |
| NGFR | 9534 |
| LINGO1 | 9141 |
| OMG | 8972 |
| NGF | 4255 |
| RHOA | 1452 |
| ARHGDIA | 1306 |
| RTN4 | -3055 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RTN4R | 10240 |
| MAG | 10080 |
| NGFR | 9534 |
| LINGO1 | 9141 |
| OMG | 8972 |
| NGF | 4255 |
| RHOA | 1452 |
| ARHGDIA | 1306 |
| RTN4 | -3055 |
REACTOME_DISSOLUTION_OF_FIBRIN_CLOT
| 1189 | |
|---|---|
| set | REACTOME_DISSOLUTION_OF_FIBRIN_CLOT |
| setSize | 13 |
| pANOVA | 0.00969 |
| s.dist | -0.414 |
| p.adjustANOVA | 0.775 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| SERPINB2 | -10597 |
| PLAUR | -9746 |
| PLAU | -9390 |
| SERPINE1 | -8113 |
| ANXA2 | -7876 |
| S100A10 | -7784 |
| SERPINB8 | -6515 |
| SERPINE2 | -6449 |
| SERPINB6 | -2519 |
| PLG | 1257 |
| HRG | 3342 |
| PLAT | 3668 |
| SERPINF2 | 4975 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SERPINB2 | -10597 |
| PLAUR | -9746 |
| PLAU | -9390 |
| SERPINE1 | -8113 |
| ANXA2 | -7876 |
| S100A10 | -7784 |
| SERPINB8 | -6515 |
| SERPINE2 | -6449 |
| SERPINB6 | -2519 |
| PLG | 1257 |
| HRG | 3342 |
| PLAT | 3668 |
| SERPINF2 | 4975 |
REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_KERATINOCYTES
| 1283 | |
|---|---|
| set | REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_KERATINOCYTES |
| setSize | 8 |
| pANOVA | 0.00991 |
| s.dist | -0.527 |
| p.adjustANOVA | 0.775 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CTSL | -10503 |
| CTSV | -10183 |
| CTSK | -8475 |
| SOCS3 | -7888 |
| RUNX1 | -6335 |
| SOCS4 | -4035 |
| CBFB | -545 |
| SERPINB13 | 3777 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CTSL | -10503 |
| CTSV | -10183 |
| CTSK | -8475 |
| SOCS3 | -7888 |
| RUNX1 | -6335 |
| SOCS4 | -4035 |
| CBFB | -545 |
| SERPINB13 | 3777 |
REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS
| 662 | |
|---|---|
| set | REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS |
| setSize | 14 |
| pANOVA | 0.0104 |
| s.dist | -0.395 |
| p.adjustANOVA | 0.777 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| OXER1 | -10605 |
| LTB4R2 | -10488 |
| LTB4R | -10423 |
| PTGIR | -10290 |
| CYSLTR2 | -10232 |
| PTGFR | -7615 |
| TBXA2R | -5147 |
| PTGDR2 | -5008 |
| PTGER2 | -2231 |
| PTGER4 | -887 |
| PTGDR | -110 |
| PTGER3 | 1515 |
| PTGER1 | 5318 |
| GPR17 | 9080 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| OXER1 | -10605 |
| LTB4R2 | -10488 |
| LTB4R | -10423 |
| PTGIR | -10290 |
| CYSLTR2 | -10232 |
| PTGFR | -7615 |
| TBXA2R | -5147 |
| PTGDR2 | -5008 |
| PTGER2 | -2231 |
| PTGER4 | -887 |
| PTGDR | -110 |
| PTGER3 | 1515 |
| PTGER1 | 5318 |
| GPR17 | 9080 |
REACTOME_SYNTHESIS_OF_LIPOXINS_LX
| 448 | |
|---|---|
| set | REACTOME_SYNTHESIS_OF_LIPOXINS_LX |
| setSize | 6 |
| pANOVA | 0.0112 |
| s.dist | -0.598 |
| p.adjustANOVA | 0.798 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| ALOX5AP | -10385 |
| LTC4S | -9412 |
| HPGD | -6556 |
| ALOX5 | -4854 |
| PTGR1 | -3370 |
| ALOX12 | -3287 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ALOX5AP | -10385 |
| LTC4S | -9412 |
| HPGD | -6556 |
| ALOX5 | -4854 |
| PTGR1 | -3370 |
| ALOX12 | -3287 |
REACTOME_TRANSCRIPTIONAL_REGULATION_BY_NPAS4
| 1492 | |
|---|---|
| set | REACTOME_TRANSCRIPTIONAL_REGULATION_BY_NPAS4 |
| setSize | 33 |
| pANOVA | 0.0123 |
| s.dist | 0.252 |
| p.adjustANOVA | 0.798 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| INS | 11091 |
| MAPK3 | 9611 |
| NAMPT | 8583 |
| MOV10 | 7867 |
| MDM2 | 7356 |
| KCNIP3 | 7183 |
| NPAS4 | 6886 |
| CDK5 | 6173 |
| FOS | 5858 |
| MAPK1 | 5363 |
| IQSEC3 | 4798 |
| NR3C1 | 4694 |
| CREBBP | 4419 |
| RET | 4349 |
| TNRC6B | 4084 |
| TNRC6A | 3987 |
| AGO1 | 3861 |
| SRF | 3488 |
| ARNT | 3121 |
| CDK5R1 | 2482 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| INS | 11091 |
| MAPK3 | 9611 |
| NAMPT | 8583 |
| MOV10 | 7867 |
| MDM2 | 7356 |
| KCNIP3 | 7183 |
| NPAS4 | 6886 |
| CDK5 | 6173 |
| FOS | 5858 |
| MAPK1 | 5363 |
| IQSEC3 | 4798 |
| NR3C1 | 4694 |
| CREBBP | 4419 |
| RET | 4349 |
| TNRC6B | 4084 |
| TNRC6A | 3987 |
| AGO1 | 3861 |
| SRF | 3488 |
| ARNT | 3121 |
| CDK5R1 | 2482 |
| AGO2 | 2401 |
| ARNT2 | 2106 |
| AGO3 | 1570 |
| BMAL1 | 1218 |
| PLK2 | 604 |
| RBFOX3 | 418 |
| SYT10 | 383 |
| TNRC6C | -895 |
| REST | -1502 |
| XPO1 | -2648 |
| BDNF | -5161 |
| GEM | -5938 |
| AGO4 | -7710 |
REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS
| 233 | |
|---|---|
| set | REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS |
| setSize | 53 |
| pANOVA | 0.0127 |
| s.dist | -0.198 |
| p.adjustANOVA | 0.798 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| NLRC4 | -10500 |
| MEFV | -10435 |
| NOD2 | -10108 |
| HMOX1 | -9915 |
| CASP1 | -9344 |
| NLRP1 | -9290 |
| NOD1 | -9273 |
| CYLD | -7471 |
| TAB1 | -6993 |
| MAPK13 | -6622 |
| CASP4 | -6453 |
| P2RX7 | -6135 |
| HSP90AB1 | -5393 |
| TXNIP | -5382 |
| PANX1 | -5356 |
| TAB2 | -5165 |
| ITCH | -5021 |
| CASP2 | -4839 |
| TNFAIP3 | -4821 |
| BIRC3 | -4734 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| NLRC4 | -10500 |
| MEFV | -10435 |
| NOD2 | -10108 |
| HMOX1 | -9915 |
| CASP1 | -9344 |
| NLRP1 | -9290 |
| NOD1 | -9273 |
| CYLD | -7471 |
| TAB1 | -6993 |
| MAPK13 | -6622 |
| CASP4 | -6453 |
| P2RX7 | -6135 |
| HSP90AB1 | -5393 |
| TXNIP | -5382 |
| PANX1 | -5356 |
| TAB2 | -5165 |
| ITCH | -5021 |
| CASP2 | -4839 |
| TNFAIP3 | -4821 |
| BIRC3 | -4734 |
| UBE2N | -4635 |
| NLRP3 | -4150 |
| CHUK | -4107 |
| CASP8 | -4082 |
| MAP2K6 | -3393 |
| UBA52 | -2703 |
| IRAK2 | -2322 |
| MAP3K7 | -1908 |
| MAPK11 | -1759 |
| CARD9 | -1429 |
| RELA | -1401 |
| APP | -1312 |
| RPS27A | -595 |
| PYCARD | -512 |
| TRAF6 | -307 |
| NFKB1 | -235 |
| MAPK14 | -206 |
| CASP9 | 972 |
| PSTPIP1 | 1648 |
| SUGT1 | 1733 |
| UBB | 2521 |
| AAMP | 2764 |
| RIPK2 | 3191 |
| TXN | 3298 |
| IKBKB | 3671 |
| BIRC2 | 4438 |
| UBC | 6258 |
| NFKB2 | 6271 |
| MAPK12 | 6983 |
| BCL2 | 7671 |
| BCL2L1 | 7678 |
| AIM2 | 8055 |
| UBE2V1 | 10263 |
REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR
| 224 | |
|---|---|
| set | REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR |
| setSize | 11 |
| pANOVA | 0.013 |
| s.dist | -0.433 |
| p.adjustANOVA | 0.798 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CTSL | -10503 |
| CTSV | -10183 |
| CTSK | -8475 |
| TLR3 | -8449 |
| CTSB | -8445 |
| UNC93B1 | -6978 |
| CTSS | -5542 |
| LGMN | -2169 |
| CNPY3 | 406 |
| HSP90B1 | 2905 |
| TLR9 | 8037 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CTSL | -10503 |
| CTSV | -10183 |
| CTSK | -8475 |
| TLR3 | -8449 |
| CTSB | -8445 |
| UNC93B1 | -6978 |
| CTSS | -5542 |
| LGMN | -2169 |
| CNPY3 | 406 |
| HSP90B1 | 2905 |
| TLR9 | 8037 |
REACTOME_BIOSYNTHESIS_OF_EPA_DERIVED_SPMS
| 1397 | |
|---|---|
| set | REACTOME_BIOSYNTHESIS_OF_EPA_DERIVED_SPMS |
| setSize | 6 |
| pANOVA | 0.0131 |
| s.dist | -0.585 |
| p.adjustANOVA | 0.798 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| ALOX15 | -10084 |
| PTGS2 | -9942 |
| HPGD | -6556 |
| LTA4H | -6130 |
| ALOX5 | -4854 |
| GPX4 | 578 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ALOX15 | -10084 |
| PTGS2 | -9942 |
| HPGD | -6556 |
| LTA4H | -6130 |
| ALOX5 | -4854 |
| GPX4 | 578 |
REACTOME_RMTS_METHYLATE_HISTONE_ARGININES
| 552 | |
|---|---|
| set | REACTOME_RMTS_METHYLATE_HISTONE_ARGININES |
| setSize | 72 |
| pANOVA | 0.0141 |
| s.dist | 0.167 |
| p.adjustANOVA | 0.825 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| H2AC15 | 10709.0 |
| H4C1 | 10651.0 |
| H2AX | 10306.0 |
| H3C1 | 10218.0 |
| H4C12 | 10113.0 |
| H2AC18 | 9855.5 |
| H2AC19 | 9855.5 |
| H2AC8 | 9082.0 |
| H4C8 | 9029.0 |
| H2AC13 | 8438.0 |
| H2AC4 | 8340.0 |
| H4C13 | 8033.0 |
| SMARCA4 | 7925.0 |
| H3C10 | 7891.0 |
| JAK2 | 7317.0 |
| CARM1 | 7250.0 |
| H4C3 | 7194.0 |
| H2AC21 | 6598.0 |
| CDK4 | 6142.0 |
| WDR77 | 5988.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| H2AC15 | 10709.0 |
| H4C1 | 10651.0 |
| H2AX | 10306.0 |
| H3C1 | 10218.0 |
| H4C12 | 10113.0 |
| H2AC18 | 9855.5 |
| H2AC19 | 9855.5 |
| H2AC8 | 9082.0 |
| H4C8 | 9029.0 |
| H2AC13 | 8438.0 |
| H2AC4 | 8340.0 |
| H4C13 | 8033.0 |
| SMARCA4 | 7925.0 |
| H3C10 | 7891.0 |
| JAK2 | 7317.0 |
| CARM1 | 7250.0 |
| H4C3 | 7194.0 |
| H2AC21 | 6598.0 |
| CDK4 | 6142.0 |
| WDR77 | 5988.0 |
| RPS2 | 5848.0 |
| ACTL6B | 5412.0 |
| H2AC17 | 4984.0 |
| H3C11 | 4968.0 |
| H2AJ | 4770.0 |
| PBRM1 | 4653.0 |
| H4C5 | 4387.0 |
| CCND1 | 4286.0 |
| PRMT7 | 4243.0 |
| H4C16 | 4042.0 |
| COPRS | 3910.0 |
| H2AZ2 | 3863.0 |
| PRMT3 | 3836.0 |
| DNMT3A | 3828.0 |
| H2AC6 | 3381.0 |
| H2AC12 | 2891.0 |
| SMARCD1 | 2595.0 |
| H3C4 | 2525.0 |
| SMARCB1 | 2330.0 |
| H2AC20 | 2285.0 |
| H3C2 | 2029.0 |
| ACTL6A | 1724.0 |
| H3C6 | 864.0 |
| SMARCC2 | 729.0 |
| SMARCD3 | 526.0 |
| H4C2 | 199.0 |
| SMARCE1 | 147.0 |
| SMARCA2 | 130.0 |
| SMARCC1 | -214.0 |
| SMARCD2 | -1095.0 |
| H4C4 | -1138.0 |
| H3C8 | -1150.0 |
| WDR5 | -1527.0 |
| H2AC25 | -1648.0 |
| ARID1A | -1676.0 |
| PRMT1 | -2053.0 |
| H2AC1 | -2471.0 |
| H2AC16 | -3014.0 |
| H2AC11 | -3128.0 |
| H2AZ1 | -4030.0 |
| H3C3 | -4580.0 |
| H3C12 | -4627.0 |
| PRMT6 | -5053.0 |
| ARID2 | -5122.0 |
| H2AC7 | -5404.5 |
| ARID1B | -5979.0 |
| H3C7 | -6699.5 |
| H4C9 | -7897.0 |
| H4C11 | -8237.0 |
| PRMT5 | -9252.0 |
| H4C6 | -9274.0 |
| H2AC14 | -9598.0 |
REACTOME_INTERLEUKIN_36_PATHWAY
| 1393 | |
|---|---|
| set | REACTOME_INTERLEUKIN_36_PATHWAY |
| setSize | 7 |
| pANOVA | 0.0155 |
| s.dist | 0.528 |
| p.adjustANOVA | 0.876 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| IL36B | 10267 |
| IL1F10 | 10264 |
| IL36RN | 9997 |
| IL36G | 9925 |
| IL1RL2 | 7639 |
| IL1RAP | -1134 |
| IL36A | -4397 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IL36B | 10267 |
| IL1F10 | 10264 |
| IL36RN | 9997 |
| IL36G | 9925 |
| IL1RL2 | 7639 |
| IL1RAP | -1134 |
| IL36A | -4397 |
REACTOME_POU5F1_OCT4_SOX2_NANOG_ACTIVATE_GENES_RELATED_TO_PROLIFERATION
| 526 | |
|---|---|
| set | REACTOME_POU5F1_OCT4_SOX2_NANOG_ACTIVATE_GENES_RELATED_TO_PROLIFERATION |
| setSize | 11 |
| pANOVA | 0.0172 |
| s.dist | -0.415 |
| p.adjustANOVA | 0.944 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| DPPA4 | -10508 |
| NANOG | -9840 |
| SALL1 | -9665 |
| SOX2 | -5950 |
| NR6A1 | -5278 |
| FOXD3 | -3733 |
| POU5F1 | -3092 |
| STAT3 | -1377 |
| EPHA1 | -26 |
| SALL4 | 452 |
| FGF2 | 1798 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| DPPA4 | -10508 |
| NANOG | -9840 |
| SALL1 | -9665 |
| SOX2 | -5950 |
| NR6A1 | -5278 |
| FOXD3 | -3733 |
| POU5F1 | -3092 |
| STAT3 | -1377 |
| EPHA1 | -26 |
| SALL4 | 452 |
| FGF2 | 1798 |
REACTOME_SURFACTANT_METABOLISM
| 992 | |
|---|---|
| set | REACTOME_SURFACTANT_METABOLISM |
| setSize | 28 |
| pANOVA | 0.0188 |
| s.dist | 0.257 |
| p.adjustANOVA | 0.957 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| SLC34A1 | 11146 |
| ADORA2A | 11096 |
| NAPSA | 10960 |
| PGA5 | 10417 |
| PGA3 | 10296 |
| SFTPA1 | 8962 |
| DMBT1 | 8946 |
| ADRA2C | 8746 |
| SFTPA2 | 8467 |
| ADGRF5 | 8266 |
| LMCD1 | 6888 |
| ABCA3 | 6822 |
| SFTPC | 5669 |
| TTF1 | 4696 |
| CCDC59 | 3384 |
| CTSH | 2588 |
| SFTA3 | 2126 |
| P2RY2 | 1434 |
| CKAP4 | 1283 |
| ZDHHC2 | -626 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SLC34A1 | 11146 |
| ADORA2A | 11096 |
| NAPSA | 10960 |
| PGA5 | 10417 |
| PGA3 | 10296 |
| SFTPA1 | 8962 |
| DMBT1 | 8946 |
| ADRA2C | 8746 |
| SFTPA2 | 8467 |
| ADGRF5 | 8266 |
| LMCD1 | 6888 |
| ABCA3 | 6822 |
| SFTPC | 5669 |
| TTF1 | 4696 |
| CCDC59 | 3384 |
| CTSH | 2588 |
| SFTA3 | 2126 |
| P2RY2 | 1434 |
| CKAP4 | 1283 |
| ZDHHC2 | -626 |
| SFTPD | -1847 |
| SLC34A2 | -3802 |
| GATA6 | -4720 |
| ADRA2A | -5268 |
| ADORA2B | -6438 |
| ADA2 | -6710 |
| CSF2RB | -8167 |
| SFTPB | -8183 |
REACTOME_GLUTAMATE_AND_GLUTAMINE_METABOLISM
| 1339 | |
|---|---|
| set | REACTOME_GLUTAMATE_AND_GLUTAMINE_METABOLISM |
| setSize | 13 |
| pANOVA | 0.0188 |
| s.dist | -0.376 |
| p.adjustANOVA | 0.957 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| OAT | -9767 |
| RIMKLA | -9416 |
| GLS2 | -8095 |
| PYCR2 | -7589 |
| RIMKLB | -7230 |
| PYCR1 | -7199 |
| GLUL | -5532 |
| GLUD1 | -1844 |
| GOT2 | -222 |
| ALDH18A1 | -9 |
| PYCR3 | 926 |
| KYAT1 | 2428 |
| GLS | 3240 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| OAT | -9767 |
| RIMKLA | -9416 |
| GLS2 | -8095 |
| PYCR2 | -7589 |
| RIMKLB | -7230 |
| PYCR1 | -7199 |
| GLUL | -5532 |
| GLUD1 | -1844 |
| GOT2 | -222 |
| ALDH18A1 | -9 |
| PYCR3 | 926 |
| KYAT1 | 2428 |
| GLS | 3240 |
REACTOME_TRANSCRIPTIONAL_REGULATION_OF_PLURIPOTENT_STEM_CELLS
| 815 | |
|---|---|
| set | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_PLURIPOTENT_STEM_CELLS |
| setSize | 29 |
| pANOVA | 0.0192 |
| s.dist | -0.251 |
| p.adjustANOVA | 0.957 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| DPPA4 | -10508 |
| GSC | -10178 |
| NANOG | -9840 |
| SALL1 | -9665 |
| CDX2 | -9198 |
| HHEX | -9165 |
| DKK1 | -8178 |
| SOX2 | -5950 |
| TSC22D1 | -5411 |
| NR6A1 | -5278 |
| GATA6 | -4720 |
| KLF4 | -4099 |
| FOXD3 | -3733 |
| FOXP1 | -3182 |
| POU5F1 | -3092 |
| SMAD2 | -2141 |
| PRDM14 | -2120 |
| HIF3A | -1378 |
| STAT3 | -1377 |
| EPHA1 | -26 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| DPPA4 | -10508 |
| GSC | -10178 |
| NANOG | -9840 |
| SALL1 | -9665 |
| CDX2 | -9198 |
| HHEX | -9165 |
| DKK1 | -8178 |
| SOX2 | -5950 |
| TSC22D1 | -5411 |
| NR6A1 | -5278 |
| GATA6 | -4720 |
| KLF4 | -4099 |
| FOXD3 | -3733 |
| FOXP1 | -3182 |
| POU5F1 | -3092 |
| SMAD2 | -2141 |
| PRDM14 | -2120 |
| HIF3A | -1378 |
| STAT3 | -1377 |
| EPHA1 | -26 |
| SALL4 | 452 |
| EPAS1 | 1687 |
| FGF2 | 1798 |
| LIN28A | 1817 |
| SMAD4 | 3112 |
| EOMES | 4669 |
| PBX1 | 6108 |
| ZSCAN10 | 7528 |
| NR5A1 | 9803 |
REACTOME_ORGANIC_ANION_TRANSPORT
| 898 | |
|---|---|
| set | REACTOME_ORGANIC_ANION_TRANSPORT |
| setSize | 5 |
| pANOVA | 0.0202 |
| s.dist | 0.6 |
| p.adjustANOVA | 0.976 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| SLC22A8 | 9728 |
| SLC22A11 | 6937 |
| SLC22A6 | 6785 |
| SLC22A7 | 6577 |
| SLC22A12 | 4299 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SLC22A8 | 9728 |
| SLC22A11 | 6937 |
| SLC22A6 | 6785 |
| SLC22A7 | 6577 |
| SLC22A12 | 4299 |
REACTOME_CREATINE_METABOLISM
| 1134 | |
|---|---|
| set | REACTOME_CREATINE_METABOLISM |
| setSize | 9 |
| pANOVA | 0.021 |
| s.dist | -0.444 |
| p.adjustANOVA | 0.977 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CKM | -9869 |
| GAMT | -8106 |
| CKMT1B | -7536 |
| GATM | -7062 |
| SLC6A7 | -6755 |
| CKB | -1768 |
| CKMT2 | -1274 |
| SLC6A11 | -233 |
| SLC6A12 | 1029 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CKM | -9869 |
| GAMT | -8106 |
| CKMT1B | -7536 |
| GATM | -7062 |
| SLC6A7 | -6755 |
| CKB | -1768 |
| CKMT2 | -1274 |
| SLC6A11 | -233 |
| SLC6A12 | 1029 |
REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING
| 333 | |
|---|---|
| set | REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING |
| setSize | 89 |
| pANOVA | 0.0218 |
| s.dist | 0.141 |
| p.adjustANOVA | 0.977 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| ARHGEF5 | 11210 |
| RTN4R | 10240 |
| MAG | 10080 |
| ARHGEF40 | 9567 |
| NGFR | 9534 |
| MYD88 | 9531 |
| LINGO1 | 9141 |
| OMG | 8972 |
| ARHGEF16 | 8591 |
| ARHGEF1 | 8545 |
| FGD3 | 8453 |
| ARHGEF15 | 8234 |
| ARHGEF38 | 8167 |
| PSENEN | 7924 |
| FGD2 | 7644 |
| SMPD2 | 7469 |
| ARHGEF11 | 6649 |
| OBSCN | 6572 |
| UBC | 6258 |
| ARHGEF17 | 6214 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ARHGEF5 | 11210 |
| RTN4R | 10240 |
| MAG | 10080 |
| ARHGEF40 | 9567 |
| NGFR | 9534 |
| MYD88 | 9531 |
| LINGO1 | 9141 |
| OMG | 8972 |
| ARHGEF16 | 8591 |
| ARHGEF1 | 8545 |
| FGD3 | 8453 |
| ARHGEF15 | 8234 |
| ARHGEF38 | 8167 |
| PSENEN | 7924 |
| FGD2 | 7644 |
| SMPD2 | 7469 |
| ARHGEF11 | 6649 |
| OBSCN | 6572 |
| UBC | 6258 |
| ARHGEF17 | 6214 |
| SOS2 | 6175 |
| MAPK8 | 5891 |
| PSEN2 | 5250 |
| ARHGEF7 | 5202 |
| NGEF | 4843 |
| HDAC1 | 4821 |
| GNA13 | 4668 |
| PREX1 | 4532 |
| PLEKHG5 | 4350 |
| VAV1 | 4284 |
| NGF | 4255 |
| VAV2 | 3739 |
| IKBKB | 3671 |
| ARHGEF4 | 3606 |
| TRIO | 3491 |
| RIPK2 | 3191 |
| TIAM1 | 2795 |
| ARHGEF3 | 2716 |
| UBB | 2521 |
| YWHAE | 2327 |
| NFKBIA | 2178 |
| VAV3 | 1454 |
| RHOA | 1452 |
| ARHGDIA | 1306 |
| ITSN1 | 1222 |
| NCSTN | 1050 |
| ARHGEF10 | 818 |
| SOS1 | 754 |
| SQSTM1 | 694 |
| ARHGEF10L | 669 |
| APH1B | 601 |
| MCF2L | 303 |
| ARHGEF18 | 51 |
| ARHGEF19 | 35 |
| BCL2L11 | 13 |
| ADAM17 | -111 |
| BAD | -195 |
| NFKB1 | -235 |
| RASGRF2 | -248 |
| RAC1 | -259 |
| TRAF6 | -307 |
| ITGB3BP | -520 |
| RPS27A | -595 |
| ARHGEF2 | -621 |
| HDAC3 | -642 |
| PLEKHG2 | -1298 |
| ARHGEF12 | -1322 |
| RELA | -1401 |
| ARHGEF26 | -1890 |
| ARHGEF39 | -2143 |
| AKAP13 | -2287 |
| KALRN | -2498 |
| UBA52 | -2703 |
| PSEN1 | -2862 |
| RTN4 | -3055 |
| ABR | -3271 |
| ECT2 | -3335 |
| PRDM4 | -3433 |
| ARHGEF37 | -3952 |
| NET1 | -4812 |
| CASP3 | -4825 |
| CASP2 | -4839 |
| ARHGEF33 | -5593 |
| AATF | -5831 |
| HDAC2 | -6075 |
| TIAM2 | -6120 |
| APH1A | -7351 |
| FGD4 | -8730 |
| PRKCI | -9473 |
REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION
| 1163 | |
|---|---|
| set | REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION |
| setSize | 102 |
| pANOVA | 0.0222 |
| s.dist | 0.131 |
| p.adjustANOVA | 0.977 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| H2BC15 | 10839.0 |
| H4C1 | 10651.0 |
| H2AX | 10306.0 |
| H3C1 | 10218.0 |
| POLR1E | 10201.0 |
| H4C12 | 10113.0 |
| H2AC18 | 9855.5 |
| H2AC19 | 9855.5 |
| POLR2E | 9697.0 |
| MAPK3 | 9611.0 |
| H2AC8 | 9082.0 |
| H4C8 | 9029.0 |
| H3-3A | 8563.0 |
| H2AC4 | 8340.0 |
| CCNH | 8195.0 |
| H4C13 | 8033.0 |
| H3C10 | 7891.0 |
| POLR1A | 7518.0 |
| MBD3 | 7490.0 |
| H4C3 | 7194.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| H2BC15 | 10839.0 |
| H4C1 | 10651.0 |
| H2AX | 10306.0 |
| H3C1 | 10218.0 |
| POLR1E | 10201.0 |
| H4C12 | 10113.0 |
| H2AC18 | 9855.5 |
| H2AC19 | 9855.5 |
| POLR2E | 9697.0 |
| MAPK3 | 9611.0 |
| H2AC8 | 9082.0 |
| H4C8 | 9029.0 |
| H3-3A | 8563.0 |
| H2AC4 | 8340.0 |
| CCNH | 8195.0 |
| H4C13 | 8033.0 |
| H3C10 | 7891.0 |
| POLR1A | 7518.0 |
| MBD3 | 7490.0 |
| H4C3 | 7194.0 |
| H2BC8 | 7101.0 |
| MNAT1 | 6855.0 |
| POLR1C | 6758.0 |
| MTA3 | 6413.0 |
| POLR2F | 6105.0 |
| H3-3B | 5879.0 |
| MTA1 | 5853.0 |
| EHMT2 | 5817.0 |
| MBD2 | 5813.0 |
| KAT2A | 5764.0 |
| POLR2L | 5720.0 |
| H2BC6 | 5593.0 |
| H3C11 | 4968.0 |
| RRN3 | 4882.0 |
| HDAC1 | 4821.0 |
| H2AJ | 4770.0 |
| POLR2K | 4721.0 |
| TTF1 | 4696.0 |
| GATAD2B | 4643.0 |
| GTF2H1 | 4490.0 |
| H4C5 | 4387.0 |
| H4C16 | 4042.0 |
| GTF2H4 | 3930.0 |
| H2AZ2 | 3863.0 |
| CDK7 | 3673.0 |
| RBBP4 | 3578.0 |
| POLR1D | 3442.0 |
| H2BC21 | 3429.0 |
| H2AC6 | 3381.0 |
| GATAD2A | 3222.0 |
| CHD3 | 2868.0 |
| H2BC1 | 2598.0 |
| H3C4 | 2525.0 |
| ERCC6 | 2359.0 |
| H2AC20 | 2285.0 |
| GTF2H5 | 2042.0 |
| H3C2 | 2029.0 |
| H2BC13 | 1357.0 |
| POLR1B | 1290.0 |
| UBTF | 971.0 |
| CHD4 | 866.0 |
| H3C6 | 864.0 |
| H2BC4 | 514.0 |
| H4C2 | 199.0 |
| POLR1F | 126.0 |
| TAF1C | 56.0 |
| ERCC2 | -113.0 |
| H2BC5 | -395.0 |
| POLR1H | -859.0 |
| H4C4 | -1138.0 |
| H3C8 | -1150.0 |
| CBX3 | -1244.0 |
| CAVIN1 | -2316.0 |
| KAT2B | -3041.0 |
| H2BC3 | -3155.0 |
| H2BC17 | -3157.0 |
| H2AZ1 | -4030.0 |
| POLR1G | -4309.0 |
| TAF1A | -4338.0 |
| H2BC12 | -4430.0 |
| H3C3 | -4580.0 |
| H3C12 | -4627.0 |
| TAF1B | -4695.0 |
| TBP | -4735.0 |
| H2BC10 | -4928.0 |
| TAF1D | -5030.0 |
| GTF2H3 | -5213.0 |
| H2AC7 | -5404.5 |
| H2BC7 | -5404.5 |
| POLR2H | -5613.0 |
| HDAC2 | -6075.0 |
| H2BC9 | -6699.5 |
| H3C7 | -6699.5 |
| MTA2 | -6912.0 |
| H2BC26 | -7080.0 |
| H4C9 | -7897.0 |
| H4C11 | -8237.0 |
| H2BC14 | -9012.0 |
| H4C6 | -9274.0 |
| ERCC3 | -9410.0 |
| H2AC14 | -9598.0 |
| H2BC11 | -9738.0 |
REACTOME_CHK1_CHK2_CDS1_MEDIATED_INACTIVATION_OF_CYCLIN_B_CDK1_COMPLEX
| 1181 | |
|---|---|
| set | REACTOME_CHK1_CHK2_CDS1_MEDIATED_INACTIVATION_OF_CYCLIN_B_CDK1_COMPLEX |
| setSize | 13 |
| pANOVA | 0.024 |
| s.dist | -0.362 |
| p.adjustANOVA | 0.977 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| SFN | -9317 |
| YWHAG | -8443 |
| YWHAQ | -8229 |
| YWHAH | -7418 |
| CDK1 | -6366 |
| CCNB1 | -4414 |
| YWHAB | -4289 |
| CDC25C | -3185 |
| CHEK2 | -2701 |
| CHEK1 | -225 |
| WEE1 | 794 |
| YWHAE | 2327 |
| YWHAZ | 3254 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SFN | -9317 |
| YWHAG | -8443 |
| YWHAQ | -8229 |
| YWHAH | -7418 |
| CDK1 | -6366 |
| CCNB1 | -4414 |
| YWHAB | -4289 |
| CDC25C | -3185 |
| CHEK2 | -2701 |
| CHEK1 | -225 |
| WEE1 | 794 |
| YWHAE | 2327 |
| YWHAZ | 3254 |
REACTOME_BIOTIN_TRANSPORT_AND_METABOLISM
| 351 | |
|---|---|
| set | REACTOME_BIOTIN_TRANSPORT_AND_METABOLISM |
| setSize | 10 |
| pANOVA | 0.0241 |
| s.dist | -0.412 |
| p.adjustANOVA | 0.977 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| PCCB | -8316 |
| ACACA | -7665 |
| ACACB | -6537 |
| BTD | -6309 |
| SLC5A6 | -5770 |
| HLCS | -5080 |
| MCCC2 | -4747 |
| MCCC1 | -4075 |
| PCCA | -523 |
| PC | 6403 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| PCCB | -8316 |
| ACACA | -7665 |
| ACACB | -6537 |
| BTD | -6309 |
| SLC5A6 | -5770 |
| HLCS | -5080 |
| MCCC2 | -4747 |
| MCCC1 | -4075 |
| PCCA | -523 |
| PC | 6403 |
REACTOME_NPAS4_REGULATES_EXPRESSION_OF_TARGET_GENES
| 1621 | |
|---|---|
| set | REACTOME_NPAS4_REGULATES_EXPRESSION_OF_TARGET_GENES |
| setSize | 21 |
| pANOVA | 0.0245 |
| s.dist | 0.283 |
| p.adjustANOVA | 0.977 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| INS | 11091 |
| MAPK3 | 9611 |
| NAMPT | 8583 |
| MDM2 | 7356 |
| NPAS4 | 6886 |
| CDK5 | 6173 |
| FOS | 5858 |
| MAPK1 | 5363 |
| IQSEC3 | 4798 |
| CREBBP | 4419 |
| RET | 4349 |
| ARNT | 3121 |
| CDK5R1 | 2482 |
| ARNT2 | 2106 |
| BMAL1 | 1218 |
| PLK2 | 604 |
| RBFOX3 | 418 |
| SYT10 | 383 |
| XPO1 | -2648 |
| BDNF | -5161 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| INS | 11091 |
| MAPK3 | 9611 |
| NAMPT | 8583 |
| MDM2 | 7356 |
| NPAS4 | 6886 |
| CDK5 | 6173 |
| FOS | 5858 |
| MAPK1 | 5363 |
| IQSEC3 | 4798 |
| CREBBP | 4419 |
| RET | 4349 |
| ARNT | 3121 |
| CDK5R1 | 2482 |
| ARNT2 | 2106 |
| BMAL1 | 1218 |
| PLK2 | 604 |
| RBFOX3 | 418 |
| SYT10 | 383 |
| XPO1 | -2648 |
| BDNF | -5161 |
| GEM | -5938 |
REACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS
| 95 | |
|---|---|
| set | REACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS |
| setSize | 17 |
| pANOVA | 0.0251 |
| s.dist | 0.314 |
| p.adjustANOVA | 0.977 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| ABCA2 | 9293 |
| ABCA10 | 9158 |
| ABCA9 | 8814 |
| ABCA6 | 8217 |
| ABCG4 | 8115 |
| ABCA3 | 6822 |
| APOA1 | 6606 |
| ABCD3 | 5936 |
| ABCA7 | 5789 |
| ABCG1 | 5647 |
| PEX3 | 5288 |
| ABCD2 | 5246 |
| ABCG8 | -1040 |
| ABCA12 | -2179 |
| ABCG5 | -3540 |
| PEX19 | -5682 |
| ABCA5 | -9296 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ABCA2 | 9293 |
| ABCA10 | 9158 |
| ABCA9 | 8814 |
| ABCA6 | 8217 |
| ABCG4 | 8115 |
| ABCA3 | 6822 |
| APOA1 | 6606 |
| ABCD3 | 5936 |
| ABCA7 | 5789 |
| ABCG1 | 5647 |
| PEX3 | 5288 |
| ABCD2 | 5246 |
| ABCG8 | -1040 |
| ABCA12 | -2179 |
| ABCG5 | -3540 |
| PEX19 | -5682 |
| ABCA5 | -9296 |
REACTOME_COLLAGEN_CHAIN_TRIMERIZATION
| 1299 | |
|---|---|
| set | REACTOME_COLLAGEN_CHAIN_TRIMERIZATION |
| setSize | 42 |
| pANOVA | 0.0262 |
| s.dist | 0.198 |
| p.adjustANOVA | 0.977 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| COL3A1 | 10666 |
| COL1A1 | 10324 |
| COL5A2 | 10298 |
| COL9A3 | 10012 |
| COL18A1 | 9735 |
| COL11A2 | 9156 |
| COL5A1 | 8607 |
| COL27A1 | 8456 |
| COL13A1 | 8151 |
| COL11A1 | 7868 |
| COL23A1 | 7781 |
| COL6A6 | 7452 |
| COL7A1 | 7095 |
| COL4A3 | 6632 |
| COL17A1 | 6567 |
| COL22A1 | 6116 |
| COL26A1 | 4635 |
| COL8A2 | 4500 |
| COL6A3 | 4444 |
| COL6A2 | 3880 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| COL3A1 | 10666 |
| COL1A1 | 10324 |
| COL5A2 | 10298 |
| COL9A3 | 10012 |
| COL18A1 | 9735 |
| COL11A2 | 9156 |
| COL5A1 | 8607 |
| COL27A1 | 8456 |
| COL13A1 | 8151 |
| COL11A1 | 7868 |
| COL23A1 | 7781 |
| COL6A6 | 7452 |
| COL7A1 | 7095 |
| COL4A3 | 6632 |
| COL17A1 | 6567 |
| COL22A1 | 6116 |
| COL26A1 | 4635 |
| COL8A2 | 4500 |
| COL6A3 | 4444 |
| COL6A2 | 3880 |
| COL6A5 | 2908 |
| COL2A1 | 2874 |
| COL8A1 | 1927 |
| COL9A1 | 1381 |
| COL4A4 | 1128 |
| COL6A1 | 1016 |
| COL25A1 | 883 |
| COL19A1 | 379 |
| COL9A2 | 82 |
| COL4A2 | -2079 |
| COL21A1 | -2628 |
| COL1A2 | -3229 |
| COL14A1 | -3432 |
| COL16A1 | -3435 |
| COL15A1 | -4071 |
| COL28A1 | -4184 |
| COL4A1 | -4406 |
| COL12A1 | -5318 |
| COL20A1 | -5666 |
| COL24A1 | -7522 |
| COL10A1 | -7608 |
| COL5A3 | -8652 |
REACTOME_PURINERGIC_SIGNALING_IN_LEISHMANIASIS_INFECTION
| 1514 | |
|---|---|
| set | REACTOME_PURINERGIC_SIGNALING_IN_LEISHMANIASIS_INFECTION |
| setSize | 26 |
| pANOVA | 0.027 |
| s.dist | -0.251 |
| p.adjustANOVA | 0.977 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| IL1B | -10484 |
| MEFV | -10435 |
| CTSG | -10433 |
| HMOX1 | -9915 |
| CASP1 | -9344 |
| ENTPD1 | -7439 |
| P2RX7 | -6135 |
| HSP90AB1 | -5393 |
| TXNIP | -5382 |
| IL1A | -4744 |
| NLRP3 | -4150 |
| GSDMD | -2968 |
| RELA | -1401 |
| APP | -1312 |
| IL18 | -967 |
| ENTPD5 | -653 |
| PYCARD | -512 |
| NFKB1 | -235 |
| PSTPIP1 | 1648 |
| SUGT1 | 1733 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IL1B | -10484 |
| MEFV | -10435 |
| CTSG | -10433 |
| HMOX1 | -9915 |
| CASP1 | -9344 |
| ENTPD1 | -7439 |
| P2RX7 | -6135 |
| HSP90AB1 | -5393 |
| TXNIP | -5382 |
| IL1A | -4744 |
| NLRP3 | -4150 |
| GSDMD | -2968 |
| RELA | -1401 |
| APP | -1312 |
| IL18 | -967 |
| ENTPD5 | -653 |
| PYCARD | -512 |
| NFKB1 | -235 |
| PSTPIP1 | 1648 |
| SUGT1 | 1733 |
| C3AR1 | 2137 |
| P2RX4 | 3076 |
| TXN | 3298 |
| C3 | 4206 |
| NT5E | 4915 |
| NFKB2 | 6271 |
REACTOME_INNATE_IMMUNE_SYSTEM
| 227 | |
|---|---|
| set | REACTOME_INNATE_IMMUNE_SYSTEM |
| setSize | 1002 |
| pANOVA | 0.0286 |
| s.dist | -0.0409 |
| p.adjustANOVA | 0.977 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| FOLR3 | -10730 |
| IFNA7 | -10725 |
| RNASE2 | -10699 |
| AZU1 | -10689 |
| ADGRG3 | -10685 |
| S100A8 | -10672 |
| CD300LB | -10666 |
| CEACAM6 | -10634 |
| CEACAM1 | -10608 |
| LRG1 | -10590 |
| STING1 | -10585 |
| DEFA4 | -10564 |
| RNASE3 | -10553 |
| CTSL | -10503 |
| MPO | -10502 |
| NLRC4 | -10500 |
| IL1B | -10484 |
| CEACAM3 | -10478 |
| LYZ | -10459 |
| MS4A3 | -10440 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| FOLR3 | -10730.0 |
| IFNA7 | -10725.0 |
| RNASE2 | -10699.0 |
| AZU1 | -10689.0 |
| ADGRG3 | -10685.0 |
| S100A8 | -10672.0 |
| CD300LB | -10666.0 |
| CEACAM6 | -10634.0 |
| CEACAM1 | -10608.0 |
| LRG1 | -10590.0 |
| STING1 | -10585.0 |
| DEFA4 | -10564.0 |
| RNASE3 | -10553.0 |
| CTSL | -10503.0 |
| MPO | -10502.0 |
| NLRC4 | -10500.0 |
| IL1B | -10484.0 |
| CEACAM3 | -10478.0 |
| LYZ | -10459.0 |
| MS4A3 | -10440.0 |
| MEFV | -10435.0 |
| CTSG | -10433.0 |
| PRTN3 | -10428.0 |
| TREM1 | -10425.0 |
| TARM1 | -10420.0 |
| IFNA21 | -10418.0 |
| C5AR1 | -10399.0 |
| AOC1 | -10355.0 |
| CHI3L1 | -10320.0 |
| FCER1G | -10315.0 |
| UBA7 | -10303.0 |
| HRNR | -10287.0 |
| CD68 | -10278.0 |
| ELANE | -10234.0 |
| DEFB125 | -10222.0 |
| ICAM2 | -10196.0 |
| CTSV | -10183.0 |
| TREX1 | -10151.0 |
| VAT1 | -10127.0 |
| NOD2 | -10108.0 |
| RHOG | -10102.0 |
| SERPINB12 | -10094.0 |
| FGR | -10083.0 |
| ATP6V1E1 | -10079.0 |
| OSCAR | -10053.0 |
| HP | -10041.0 |
| TMEM30A | -10036.0 |
| PGLYRP1 | -9918.0 |
| HMOX1 | -9915.0 |
| PRKCD | -9900.0 |
| TYROBP | -9897.0 |
| BRI3 | -9894.0 |
| CAMP | -9844.0 |
| FCGR2A | -9822.0 |
| GSTP1 | -9813.0 |
| GDI2 | -9783.0 |
| C8B | -9779.0 |
| CD46 | -9773.0 |
| PLAUR | -9746.0 |
| MNDA | -9740.0 |
| SAA1 | -9719.0 |
| DEFB1 | -9711.0 |
| NLRC5 | -9631.0 |
| FCN2 | -9605.0 |
| IRAK3 | -9580.0 |
| CTSA | -9569.0 |
| NCF2 | -9561.0 |
| PLD1 | -9558.0 |
| C5AR2 | -9550.0 |
| RAB31 | -9538.0 |
| NME2 | -9519.0 |
| RNASE6 | -9516.0 |
| RNASE8 | -9499.0 |
| PSMB7 | -9461.0 |
| C4A | -9446.5 |
| C4B | -9446.5 |
| TLR4 | -9441.0 |
| RPS6KA1 | -9417.0 |
| RNASE7 | -9395.0 |
| CAP1 | -9392.0 |
| PLAU | -9390.0 |
| LPO | -9383.0 |
| CLEC4D | -9381.0 |
| FCAR | -9371.0 |
| CASP1 | -9344.0 |
| CLEC7A | -9342.0 |
| DUSP3 | -9312.0 |
| MYH2 | -9302.0 |
| NLRP1 | -9290.0 |
| AGER | -9288.0 |
| NOD1 | -9273.0 |
| DEFB127 | -9254.0 |
| GGH | -9235.0 |
| ATG7 | -9202.0 |
| S100P | -9182.0 |
| SLC11A1 | -9175.0 |
| HTN1 | -9173.0 |
| GUSB | -9171.0 |
| S100A12 | -9152.0 |
| OLR1 | -9136.0 |
| CLEC4A | -9118.0 |
| ATP6V1C1 | -9111.0 |
| DOK3 | -9086.0 |
| CAT | -9061.0 |
| CPN1 | -9035.0 |
| SEMG1 | -9025.0 |
| POLR3C | -9001.0 |
| GMFG | -8982.0 |
| CDA | -8952.0 |
| HGSNAT | -8948.0 |
| PTPRJ | -8915.0 |
| RAB27A | -8899.0 |
| MUCL1 | -8884.0 |
| MGST1 | -8871.0 |
| SHC1 | -8777.0 |
| VNN1 | -8742.0 |
| SELL | -8736.0 |
| CXCR2 | -8734.0 |
| CD177 | -8700.0 |
| GM2A | -8683.0 |
| COMMD3 | -8672.0 |
| REG3A | -8643.0 |
| TRIM32 | -8523.0 |
| SARM1 | -8508.0 |
| CTSK | -8475.0 |
| TLR3 | -8449.0 |
| CTSB | -8445.0 |
| FCN1 | -8441.0 |
| PRG2 | -8415.0 |
| KRAS | -8414.0 |
| GSN | -8413.0 |
| ECSIT | -8412.0 |
| FTH1 | -8379.0 |
| TNFAIP6 | -8375.0 |
| PRKACA | -8371.0 |
| KPNB1 | -8302.0 |
| TICAM1 | -8269.0 |
| SLC2A3 | -8247.0 |
| NCKAP1 | -8238.0 |
| LAMTOR1 | -8223.0 |
| SERPINB10 | -8195.0 |
| HLA-B | -8160.0 |
| CREG1 | -8154.0 |
| PIK3C3 | -8103.0 |
| IFNA1 | -8008.5 |
| VCP | -8003.0 |
| BIN2 | -7947.0 |
| SYK | -7943.0 |
| BCL10 | -7934.0 |
| IMPDH1 | -7905.0 |
| ATP6V1B2 | -7902.0 |
| VPS35L | -7886.0 |
| CLEC10A | -7885.0 |
| DIAPH1 | -7877.0 |
| ANXA2 | -7876.0 |
| P2RX1 | -7860.0 |
| RAB10 | -7857.0 |
| ATP6V0A1 | -7842.0 |
| PIK3R1 | -7787.0 |
| ART1 | -7714.0 |
| VTN | -7597.0 |
| HSPA1B | -7567.0 |
| PNP | -7558.0 |
| TRIM21 | -7550.0 |
| MME | -7549.0 |
| TRIM4 | -7478.0 |
| SIRPB1 | -7476.0 |
| CYLD | -7471.0 |
| PSME4 | -7401.0 |
| COMMD9 | -7368.0 |
| POLR3D | -7366.0 |
| CTSD | -7359.0 |
| PPIA | -7358.0 |
| LIMK1 | -7315.0 |
| CPNE3 | -7304.0 |
| TCN1 | -7300.0 |
| AMPD3 | -7266.0 |
| NKIRAS2 | -7187.0 |
| CD63 | -7112.0 |
| DEFB118 | -7085.0 |
| ATP8B4 | -7013.0 |
| DYNLL1 | -7006.0 |
| TAB1 | -6993.0 |
| MS4A2 | -6990.0 |
| UNC93B1 | -6978.0 |
| NCR2 | -6950.0 |
| CEACAM8 | -6890.0 |
| CFH | -6883.0 |
| PTX3 | -6847.0 |
| ITPR1 | -6827.0 |
| SERPINB1 | -6787.0 |
| CYB5R3 | -6780.0 |
| ATG5 | -6775.0 |
| NF2 | -6769.0 |
| HLA-A | -6748.0 |
| PSMB3 | -6733.0 |
| CUL1 | -6713.0 |
| ADA2 | -6710.0 |
| TANK | -6663.0 |
| MAP2K1 | -6659.0 |
| MAPK13 | -6622.0 |
| IFNA2 | -6560.0 |
| ACTR1B | -6552.0 |
| ELMO2 | -6524.0 |
| TLR6 | -6510.0 |
| CASP4 | -6453.0 |
| PGAM1 | -6436.0 |
| AP1M1 | -6431.0 |
| AHCYL1 | -6426.0 |
| IFNA14 | -6411.0 |
| HEXB | -6399.0 |
| CFD | -6393.0 |
| GCA | -6390.0 |
| CD59 | -6368.0 |
| MMP8 | -6357.0 |
| ATP6V0E2 | -6298.0 |
| LAMTOR2 | -6295.0 |
| RAP2B | -6278.0 |
| SCAMP1 | -6275.0 |
| MYO1C | -6272.0 |
| HSPA1A | -6254.0 |
| SLCO4C1 | -6175.0 |
| MALT1 | -6153.0 |
| P2RX7 | -6135.0 |
| LTA4H | -6130.0 |
| DEFB115 | -6059.0 |
| DBNL | -6057.0 |
| DEFB104A | -6013.5 |
| DEFB104B | -6013.5 |
| MMP9 | -6001.0 |
| CRACR2A | -5970.0 |
| ELMO1 | -5925.0 |
| RAB37 | -5913.0 |
| CTNNB1 | -5911.0 |
| F2 | -5878.0 |
| POLR3E | -5874.0 |
| PGLYRP3 | -5868.0 |
| SIGLEC5 | -5797.0 |
| OSTF1 | -5796.0 |
| CD44 | -5772.0 |
| GYG1 | -5761.0 |
| RPS6KA5 | -5721.0 |
| BPIFB4 | -5684.0 |
| RBSN | -5634.0 |
| POLR3F | -5629.0 |
| TEC | -5628.0 |
| POLR2H | -5613.0 |
| RAB3D | -5558.0 |
| CTSS | -5542.0 |
| WIPF3 | -5533.0 |
| CR1 | -5511.0 |
| FAF2 | -5496.0 |
| ACLY | -5445.0 |
| CMTM6 | -5421.0 |
| CPNE1 | -5410.0 |
| HSP90AB1 | -5393.0 |
| TXNIP | -5382.0 |
| PANX1 | -5356.0 |
| NHLRC3 | -5344.0 |
| ITGAM | -5303.0 |
| MAP3K14 | -5301.0 |
| NCF4 | -5286.0 |
| KCNAB2 | -5277.0 |
| PSMC2 | -5276.0 |
| DSN1 | -5261.0 |
| PRKDC | -5226.0 |
| XRCC6 | -5223.0 |
| UBR4 | -5212.0 |
| TAB2 | -5165.0 |
| CD93 | -5139.0 |
| ADAM10 | -5133.0 |
| RELB | -5108.0 |
| DNAJC13 | -5091.0 |
| TRPM2 | -5088.0 |
| ITCH | -5021.0 |
| NFATC2 | -4991.0 |
| B4GALT1 | -4984.0 |
| IQGAP2 | -4963.0 |
| COTL1 | -4953.0 |
| CD300E | -4946.0 |
| POLR3B | -4937.0 |
| S100A9 | -4899.0 |
| UBE2L6 | -4894.0 |
| IFI16 | -4886.0 |
| VRK3 | -4878.0 |
| ALOX5 | -4854.0 |
| CASP2 | -4839.0 |
| ALAD | -4830.0 |
| TNFAIP3 | -4821.0 |
| GNS | -4789.0 |
| GAB2 | -4782.0 |
| PADI2 | -4759.0 |
| NOS2 | -4739.0 |
| BIRC3 | -4734.0 |
| LAIR1 | -4719.0 |
| CLEC12A | -4689.0 |
| TBK1 | -4666.0 |
| UBE2N | -4635.0 |
| ABL1 | -4623.0 |
| CD180 | -4612.0 |
| WIPF1 | -4611.0 |
| CD58 | -4608.0 |
| PRG3 | -4566.0 |
| SERPINA1 | -4564.0 |
| TRAF2 | -4562.0 |
| MLEC | -4561.0 |
| PLEKHO2 | -4522.0 |
| PGLYRP2 | -4468.0 |
| DEFB119 | -4459.0 |
| RNF216 | -4441.0 |
| B2M | -4432.0 |
| MRE11 | -4405.0 |
| ITPR2 | -4358.0 |
| NOS1 | -4326.0 |
| AGA | -4285.0 |
| RAP1B | -4260.0 |
| ARMC8 | -4236.0 |
| PPP3CB | -4219.0 |
| PTPN6 | -4209.0 |
| MAPK9 | -4171.0 |
| C5 | -4154.0 |
| NLRP3 | -4150.0 |
| CHUK | -4107.0 |
| CASP8 | -4082.0 |
| CLEC5A | -4078.0 |
| PSMD4 | -3996.0 |
| CRCP | -3984.0 |
| NLRX1 | -3965.0 |
| SLC2A5 | -3938.0 |
| MCEMP1 | -3937.0 |
| PLA2G6 | -3921.0 |
| FLG2 | -3911.0 |
| RAB24 | -3909.0 |
| FCGR3B | -3883.0 |
| TRIM56 | -3862.0 |
| PLPP4 | -3859.0 |
| KCMF1 | -3826.0 |
| PSMB1 | -3823.0 |
| CRISPLD2 | -3820.0 |
| MYO10 | -3734.0 |
| PSMB2 | -3722.0 |
| RAB6A | -3704.0 |
| RAB5B | -3673.0 |
| FGB | -3656.0 |
| DNAJC3 | -3652.0 |
| PSMD14 | -3626.0 |
| CTSZ | -3612.0 |
| SYNGR1 | -3560.0 |
| BPIFA1 | -3533.0 |
| RAB44 | -3520.0 |
| GPI | -3519.0 |
| CD47 | -3500.0 |
| TICAM2 | -3487.0 |
| DNM3 | -3467.0 |
| CD4 | -3466.0 |
| CYSTM1 | -3464.0 |
| NLRC3 | -3439.0 |
| SIGIRR | -3427.0 |
| MAP2K6 | -3393.0 |
| PLCG2 | -3391.0 |
| PKM | -3388.0 |
| KRT1 | -3356.0 |
| PSMA4 | -3236.0 |
| SIGLEC15 | -3197.0 |
| SLPI | -3192.0 |
| ABCA13 | -3186.0 |
| TUBB | -3184.0 |
| NCKAP1L | -3124.0 |
| PIN1 | -3115.0 |
| NCK1 | -3078.0 |
| ATP6V1E2 | -3064.0 |
| HSPA6 | -3044.0 |
| BPI | -2999.0 |
| PSMA5 | -2988.0 |
| GSDMD | -2968.0 |
| RPS6KA2 | -2953.0 |
| ITGAV | -2938.0 |
| NCKIPSD | -2910.0 |
| DEFB121 | -2891.0 |
| RAF1 | -2881.0 |
| PSAP | -2877.0 |
| EP300 | -2871.0 |
| PSEN1 | -2862.0 |
| POLR3A | -2857.0 |
| PPP2R1A | -2855.0 |
| STOM | -2841.0 |
| PSMA2 | -2839.0 |
| PSMB9 | -2790.0 |
| ARSB | -2742.0 |
| RNF135 | -2726.0 |
| UBA52 | -2703.0 |
| DERA | -2692.0 |
| DEFA6 | -2649.0 |
| PAK1 | -2647.0 |
| LRRFIP1 | -2621.0 |
| CD33 | -2590.0 |
| MAPK7 | -2580.0 |
| SVIP | -2550.0 |
| SERPINB6 | -2519.0 |
| WASF3 | -2504.0 |
| IGF2R | -2499.0 |
| IST1 | -2487.0 |
| DEFB123 | -2483.0 |
| MAP3K8 | -2439.0 |
| STK11IP | -2393.0 |
| FBXW11 | -2380.0 |
| UNC13D | -2377.0 |
| IRAK2 | -2322.0 |
| FRK | -2320.0 |
| TTR | -2303.0 |
| REG3G | -2183.0 |
| LGMN | -2169.0 |
| IFNB1 | -2156.0 |
| FPR2 | -2152.0 |
| IFIH1 | -2149.0 |
| HPSE | -2071.0 |
| BST1 | -2038.0 |
| CPB2 | -2033.0 |
| ATP6V0B | -2004.0 |
| LTF | -1996.0 |
| FGL2 | -1977.0 |
| XRCC5 | -1920.0 |
| MAP3K7 | -1908.0 |
| DDOST | -1885.0 |
| ADAM8 | -1879.0 |
| SFTPD | -1847.0 |
| PSMA8 | -1797.0 |
| MAPK11 | -1759.0 |
| PSMB8 | -1750.0 |
| HERC5 | -1741.0 |
| PELI2 | -1715.0 |
| EEF1A1 | -1701.0 |
| PPP3CA | -1677.0 |
| PSMA1 | -1674.0 |
| CAB39 | -1672.0 |
| MAPKAPK3 | -1604.0 |
| PSMD8 | -1553.0 |
| LRRC7 | -1511.0 |
| ITGAL | -1475.0 |
| SNAP25 | -1456.0 |
| HCK | -1436.0 |
| CARD9 | -1429.0 |
| CDC42 | -1417.0 |
| CANT1 | -1403.0 |
| RELA | -1401.0 |
| YES1 | -1376.0 |
| ACTG1 | -1367.0 |
| ARL8A | -1355.0 |
| C6 | -1349.0 |
| ATP6V0D1 | -1348.0 |
| APP | -1312.0 |
| ISG15 | -1296.0 |
| GRN | -1287.0 |
| S100A11 | -1262.0 |
| MAP2K7 | -1224.0 |
| TNIP2 | -1218.0 |
| GSDME | -1209.0 |
| EEA1 | -1172.0 |
| ITGAX | -1167.0 |
| C6orf120 | -1136.0 |
| WIPF2 | -1117.0 |
| PTPN4 | -1075.0 |
| YPEL5 | -1009.0 |
| RASGRP2 | -957.0 |
| DHX9 | -886.0 |
| PSMC1 | -885.0 |
| GALNS | -884.0 |
| PSMD7 | -880.0 |
| EPX | -857.0 |
| DUSP4 | -848.0 |
| GHDC | -834.0 |
| PTPRB | -815.0 |
| LILRB2 | -741.0 |
| DYNC1H1 | -731.0 |
| PRCP | -719.0 |
| VAPA | -699.0 |
| VAMP8 | -678.0 |
| MAP2K4 | -646.0 |
| RAB18 | -634.0 |
| SNAP23 | -622.0 |
| ALDH3B1 | -618.0 |
| RPS27A | -595.0 |
| CFHR4 | -563.0 |
| HSPA8 | -515.0 |
| PYCARD | -512.0 |
| DEFB132 | -504.0 |
| PSMD1 | -503.0 |
| IMPDH2 | -493.0 |
| ANO6 | -477.0 |
| QSOX1 | -473.0 |
| TXNDC5 | -445.0 |
| COLEC11 | -441.0 |
| PSMF1 | -417.0 |
| HMOX2 | -399.0 |
| DNAJC5 | -348.0 |
| CRK | -332.0 |
| TRAF6 | -307.0 |
| LGALS3 | -264.0 |
| RAC1 | -259.0 |
| NFKB1 | -235.0 |
| MAPK14 | -206.0 |
| MMP25 | -171.0 |
| PLD3 | -165.0 |
| PSMA7 | -126.0 |
| ATP6V1F | -91.0 |
| MAVS | -60.0 |
| PTPRN2 | -50.0 |
| DTX4 | 18.0 |
| IKBKE | 50.0 |
| DEFB135 | 54.0 |
| EPPIN | 93.0 |
| CHGA | 114.0 |
| TMBIM1 | 161.0 |
| FUCA2 | 182.0 |
| TMEM63A | 184.0 |
| DEFB114 | 193.0 |
| CALM1 | 217.0 |
| ADGRE3 | 237.0 |
| MUC17 | 238.0 |
| FABP5 | 264.0 |
| C1QA | 365.0 |
| MIF | 376.0 |
| CNPY3 | 406.0 |
| PSMC5 | 416.0 |
| DUSP6 | 423.0 |
| RIPK3 | 440.0 |
| AGL | 467.0 |
| IDH1 | 534.0 |
| PSMD5 | 562.0 |
| PIK3CB | 564.0 |
| TREM2 | 579.0 |
| ATF2 | 607.0 |
| ERP44 | 625.0 |
| WASL | 627.0 |
| PPP2CB | 630.0 |
| RASGRP1 | 637.0 |
| PLAC8 | 649.0 |
| VCL | 680.0 |
| SEM1 | 725.0 |
| CAPZA1 | 740.0 |
| S100B | 746.0 |
| SOS1 | 754.0 |
| PPP2CA | 766.0 |
| RAB4B | 792.0 |
| ATG12 | 839.0 |
| ATOX1 | 876.0 |
| CST3 | 888.0 |
| LYN | 889.0 |
| IRF3 | 890.0 |
| PTPN11 | 936.0 |
| BTRC | 965.0 |
| CASP9 | 972.0 |
| WASF2 | 983.0 |
| CPPED1 | 991.0 |
| DYNLT1 | 992.0 |
| NCSTN | 1050.0 |
| CFI | 1053.0 |
| ITLN1 | 1088.0 |
| PRKCE | 1110.0 |
| DOCK1 | 1169.0 |
| DNM2 | 1175.0 |
| FTL | 1190.0 |
| DOCK2 | 1202.0 |
| TRAF3 | 1215.0 |
| C1QC | 1232.0 |
| PKP1 | 1237.0 |
| MUC21 | 1269.0 |
| CKAP4 | 1283.0 |
| SURF4 | 1303.0 |
| ITPR3 | 1311.0 |
| RIPK1 | 1352.0 |
| ROCK1 | 1369.0 |
| STBD1 | 1392.0 |
| GLIPR1 | 1406.0 |
| RHOA | 1452.0 |
| VAV3 | 1454.0 |
| C1orf35 | 1470.0 |
| APRT | 1471.0 |
| SERPINA3 | 1483.0 |
| CRP | 1517.0 |
| TSPAN14 | 1526.0 |
| ATP6V1H | 1534.0 |
| PDXK | 1546.0 |
| DEFB128 | 1596.0 |
| CAPN1 | 1603.0 |
| SPTAN1 | 1620.0 |
| MYO5A | 1630.0 |
| MAP2K3 | 1639.0 |
| PSTPIP1 | 1648.0 |
| ATP11B | 1664.0 |
| PSME3 | 1671.0 |
| PPIE | 1675.0 |
| SUGT1 | 1733.0 |
| ATF1 | 1752.0 |
| BRK1 | 1777.0 |
| ALDOC | 1836.0 |
| TLR2 | 1838.0 |
| PFKL | 1843.0 |
| NEU1 | 1873.0 |
| DHX36 | 1904.0 |
| LCN2 | 1918.0 |
| PSMA6 | 1940.0 |
| DSP | 1946.0 |
| ATP11A | 1964.0 |
| PSMD3 | 1999.0 |
| TIMP2 | 2020.0 |
| MEF2C | 2047.0 |
| RAB5C | 2107.0 |
| SKP1 | 2115.0 |
| POLR3H | 2116.0 |
| C3AR1 | 2137.0 |
| NIT2 | 2157.0 |
| MAPKAPK2 | 2177.0 |
| NFKBIA | 2178.0 |
| PSMD6 | 2217.0 |
| CNN2 | 2223.0 |
| DYNC1LI1 | 2238.0 |
| CEP290 | 2251.0 |
| PGM1 | 2264.0 |
| FCER1A | 2267.0 |
| LAT2 | 2276.0 |
| TKFC | 2297.0 |
| ARG1 | 2322.0 |
| PAFAH1B2 | 2353.0 |
| PSMA3 | 2388.0 |
| TP53 | 2464.0 |
| DGAT1 | 2480.0 |
| UBB | 2521.0 |
| PELI3 | 2538.0 |
| ALPK1 | 2539.0 |
| ATP6V1D | 2563.0 |
| HLA-C | 2564.0 |
| CTSH | 2588.0 |
| PPP2R5D | 2594.0 |
| NLRP4 | 2603.0 |
| CSNK2B | 2620.0 |
| CFB | 2642.0 |
| PRKCSH | 2696.0 |
| IKBIP | 2697.0 |
| TIRAP | 2706.0 |
| PPP2R1B | 2712.0 |
| RAB3A | 2728.0 |
| TIFA | 2733.0 |
| DEGS1 | 2758.0 |
| ARPC2 | 2761.0 |
| AAMP | 2764.0 |
| CRISP3 | 2776.0 |
| FUCA1 | 2859.0 |
| HEBP2 | 2883.0 |
| ATP6V1A | 2886.0 |
| CCR2 | 2888.0 |
| WASF1 | 2894.0 |
| ABI2 | 2902.0 |
| HSP90B1 | 2905.0 |
| ATP6V0C | 2912.0 |
| RNF125 | 2925.0 |
| DHX58 | 2928.0 |
| PLPP5 | 2977.0 |
| ARPC5 | 3014.0 |
| NKIRAS1 | 3022.0 |
| N4BP1 | 3024.0 |
| CD36 | 3062.0 |
| RAP1A | 3156.0 |
| APAF1 | 3179.0 |
| RIPK2 | 3191.0 |
| ATP6V0A2 | 3192.0 |
| UBE2K | 3296.0 |
| TXN | 3298.0 |
| MEF2A | 3315.0 |
| PYGL | 3320.0 |
| BST2 | 3333.0 |
| PSMD11 | 3372.0 |
| DEFB124 | 3395.0 |
| FYN | 3400.0 |
| HSP90AA1 | 3411.0 |
| POLR1D | 3442.0 |
| CARD11 | 3447.0 |
| DUSP7 | 3478.0 |
| PRKACB | 3483.0 |
| IRF7 | 3516.0 |
| STK10 | 3518.0 |
| CCL22 | 3524.0 |
| PCBP2 | 3536.0 |
| NFAM1 | 3573.0 |
| MUC16 | 3658.0 |
| IKBKB | 3671.0 |
| PLD2 | 3729.0 |
| VAV2 | 3739.0 |
| MUC3A | 3746.0 |
| UBE2D1 | 3769.0 |
| USP14 | 3786.0 |
| PDAP1 | 3817.0 |
| UBE2D3 | 3825.0 |
| ASAH1 | 3834.0 |
| PSMB6 | 3841.0 |
| QPCT | 3842.0 |
| POLR3K | 3844.0 |
| DEFB116 | 3889.0 |
| AHSG | 3894.0 |
| SIKE1 | 3898.0 |
| TLR1 | 3924.0 |
| IRAG2 | 3948.0 |
| MUC5AC | 3970.0 |
| PSMD12 | 4000.0 |
| CYFIP1 | 4008.0 |
| RAB14 | 4015.0 |
| ATP6V1G2 | 4074.0 |
| S100A7A | 4108.0 |
| RASGRP4 | 4118.0 |
| PI3 | 4120.0 |
| CLEC4C | 4130.0 |
| ATP8A1 | 4145.0 |
| UBE2M | 4147.0 |
| CREB1 | 4166.0 |
| PTGES2 | 4172.0 |
| TOLLIP | 4192.0 |
| C3 | 4206.0 |
| RAB7A | 4213.0 |
| HBB | 4251.0 |
| POLR3GL | 4266.0 |
| VAV1 | 4284.0 |
| NRAS | 4302.0 |
| PRDX6 | 4363.0 |
| COPB1 | 4367.0 |
| TAX1BP1 | 4380.0 |
| ATP6V1C2 | 4408.0 |
| CREBBP | 4419.0 |
| BIRC2 | 4438.0 |
| MANBA | 4471.0 |
| CXCL1 | 4673.0 |
| SRP14 | 4708.0 |
| POLR2K | 4721.0 |
| DPP7 | 4727.0 |
| CDK13 | 4742.0 |
| CLU | 4744.0 |
| C2 | 4816.0 |
| SERPING1 | 4819.0 |
| PELI1 | 4835.0 |
| ACTB | 4881.0 |
| SNAP29 | 4903.0 |
| MAN2B1 | 4934.0 |
| PSMB4 | 4961.0 |
| TOM1 | 5045.0 |
| CCT2 | 5055.0 |
| GRAP2 | 5061.0 |
| ACTR10 | 5067.0 |
| RNASET2 | 5093.0 |
| GOLGA7 | 5152.0 |
| PIK3R4 | 5191.0 |
| IQGAP1 | 5259.0 |
| ALDOA | 5361.0 |
| MAPK1 | 5363.0 |
| C1QB | 5374.0 |
| GNLY | 5376.0 |
| FPR1 | 5395.0 |
| HVCN1 | 5418.0 |
| DCD | 5431.0 |
| TRIM25 | 5495.0 |
| CALML5 | 5500.0 |
| LAMTOR3 | 5509.0 |
| DSG1 | 5521.0 |
| MGAM | 5543.0 |
| C7 | 5562.0 |
| PSMC3 | 5595.0 |
| LEAP2 | 5598.0 |
| MYO9B | 5611.0 |
| GPR84 | 5663.0 |
| POLR2L | 5720.0 |
| LILRA3 | 5722.0 |
| BPIFA2 | 5751.0 |
| CDC34 | 5788.0 |
| LPCAT1 | 5808.0 |
| PLCG1 | 5821.0 |
| PRKCQ | 5824.0 |
| PSME2 | 5834.0 |
| FOS | 5858.0 |
| CLEC4E | 5888.0 |
| MAPK8 | 5891.0 |
| CASP10 | 5952.0 |
| PLA2G2A | 5958.0 |
| PTK2 | 6033.0 |
| RAC2 | 6042.0 |
| NFATC3 | 6059.0 |
| PPP3R1 | 6095.0 |
| POLR2F | 6105.0 |
| CR2 | 6128.0 |
| CPN2 | 6160.0 |
| CGAS | 6164.0 |
| NDUFC2 | 6199.0 |
| ARSA | 6207.0 |
| MUC7 | 6252.0 |
| SDCBP | 6255.0 |
| UBC | 6258.0 |
| NFKB2 | 6271.0 |
| MAPK10 | 6297.0 |
| CD81 | 6326.0 |
| PIGR | 6364.0 |
| PROS1 | 6378.0 |
| TMEM179B | 6483.0 |
| ARPC4 | 6513.0 |
| GRB2 | 6547.0 |
| ARPC1A | 6554.0 |
| PSMD13 | 6561.0 |
| PSMB5 | 6566.0 |
| MUC13 | 6580.0 |
| TRAPPC1 | 6626.0 |
| TNFRSF1B | 6635.0 |
| UBA3 | 6647.0 |
| DDX41 | 6672.0 |
| SOCS1 | 6725.0 |
| PIK3R2 | 6728.0 |
| UBE2D2 | 6730.0 |
| CFHR5 | 6744.0 |
| NFATC1 | 6757.0 |
| POLR1C | 6758.0 |
| CD14 | 6783.0 |
| ADGRE5 | 6831.0 |
| POLR3G | 6867.0 |
| GLB1 | 6882.0 |
| PSMD2 | 6891.0 |
| PDPK1 | 6912.0 |
| APEH | 6925.0 |
| PRSS3 | 6935.0 |
| MAPK12 | 6983.0 |
| LY96 | 6995.0 |
| PGM2 | 7027.0 |
| MUC15 | 7042.0 |
| ACTR3 | 7044.0 |
| NFKBIB | 7055.0 |
| NOS3 | 7059.0 |
| PAK2 | 7094.0 |
| LCP2 | 7144.0 |
| SRC | 7174.0 |
| RETN | 7175.0 |
| MBL2 | 7223.0 |
| ITGB2 | 7233.0 |
| MUC12 | 7326.0 |
| ZBP1 | 7338.0 |
| PIK3CA | 7340.0 |
| DNM1 | 7399.0 |
| CXCR1 | 7413.0 |
| MAP3K1 | 7418.0 |
| HLA-E | 7419.0 |
| RHOF | 7439.0 |
| CAND1 | 7509.0 |
| CHIT1 | 7527.0 |
| PSMD9 | 7540.0 |
| ORM2 | 7565.0 |
| JUP | 7590.0 |
| ATP6V0E1 | 7627.0 |
| ARHGAP9 | 7661.0 |
| BCL2 | 7671.0 |
| BCL2L1 | 7678.0 |
| CYFIP2 | 7680.0 |
| BAIAP2 | 7703.0 |
| CD55 | 7720.0 |
| RIGI | 7723.0 |
| ABI1 | 7745.0 |
| TOMM70 | 7749.0 |
| FGA | 7752.0 |
| NBEAL2 | 7759.0 |
| LAMP1 | 7760.0 |
| PYGB | 7771.0 |
| ATP6V1G1 | 7774.0 |
| CFL1 | 7796.0 |
| ACAA1 | 7800.0 |
| FCN3 | 7861.0 |
| AP2A2 | 7870.0 |
| CCT8 | 7910.0 |
| TMC6 | 7923.0 |
| HTN3 | 7971.0 |
| ORM1 | 7991.0 |
| TUBB4B | 8016.0 |
| TLR9 | 8037.0 |
| AIM2 | 8055.0 |
| PTAFR | 8064.0 |
| C1R | 8072.0 |
| ACTR2 | 8183.0 |
| HMGB1 | 8187.0 |
| ATP6V0D2 | 8193.0 |
| FADD | 8221.0 |
| ARPC1B | 8246.0 |
| ARHGAP45 | 8275.0 |
| NAPRT | 8285.0 |
| MUC6 | 8308.0 |
| PLD4 | 8337.0 |
| LRRC14 | 8393.0 |
| ANPEP | 8396.0 |
| PTPRC | 8415.0 |
| JUN | 8417.0 |
| PSMB10 | 8440.0 |
| CCL17 | 8442.0 |
| SFTPA2 | 8467.0 |
| BPIFB1 | 8474.0 |
| AGPAT2 | 8504.0 |
| ORMDL3 | 8553.0 |
| COLEC10 | 8572.0 |
| LILRB3 | 8576.0 |
| ARPC3 | 8616.0 |
| PSMC4 | 8618.0 |
| ILF2 | 8698.0 |
| GAA | 8699.0 |
| ENPP4 | 8733.0 |
| TXK | 8739.0 |
| PSMC6 | 8742.0 |
| NPC2 | 8779.0 |
| IRAK4 | 8789.0 |
| TCIRG1 | 8803.0 |
| USP18 | 8820.0 |
| LY86 | 8845.0 |
| SLC44A2 | 8884.0 |
| C1S | 8899.0 |
| SFTPA1 | 8962.0 |
| STAT6 | 8967.0 |
| ATP6V1G3 | 8990.0 |
| MASP1 | 9045.0 |
| IFNA8 | 9048.0 |
| PSME1 | 9064.0 |
| CHRNB4 | 9093.0 |
| ATAD3B | 9130.0 |
| CTSC | 9181.0 |
| HK3 | 9215.0 |
| EEF2 | 9252.0 |
| DEFB134 | 9257.0 |
| PA2G4 | 9263.0 |
| C8G | 9267.0 |
| KLRK1 | 9317.0 |
| MUC5B | 9326.0 |
| PSMB11 | 9358.0 |
| CYBA | 9369.0 |
| CD53 | 9379.0 |
| SERPINB3 | 9391.0 |
| IFNA16 | 9425.0 |
| ATP6V0A4 | 9449.0 |
| DEFB126 | 9483.0 |
| CSTB | 9504.0 |
| LAT | 9514.0 |
| MASP2 | 9525.0 |
| MYD88 | 9531.0 |
| ACP3 | 9557.0 |
| TLR5 | 9577.0 |
| PPBP | 9586.0 |
| MAPK3 | 9611.0 |
| MUC4 | 9620.0 |
| MVP | 9625.0 |
| SLC27A2 | 9658.0 |
| EPPIN-WFDC6 | 9664.0 |
| DSC1 | 9667.0 |
| SIRPA | 9677.0 |
| C8A | 9678.0 |
| NFASC | 9696.0 |
| POLR2E | 9697.0 |
| SIGLEC9 | 9757.0 |
| IFNA6 | 9780.0 |
| DEFB133 | 9796.0 |
| CD300A | 9871.0 |
| LBP | 9889.0 |
| DEFB110 | 9926.0 |
| CAPZA2 | 9928.0 |
| CD209 | 9940.0 |
| TLR10 | 9942.0 |
| ATP6V1B1 | 9946.0 |
| OLFM4 | 9957.0 |
| C4BPA | 9986.0 |
| MUC1 | 10023.0 |
| BPIFB2 | 10076.0 |
| PRKACG | 10084.0 |
| PGLYRP4 | 10095.0 |
| C4BPB | 10205.0 |
| MYH9 | 10221.0 |
| DEFA5 | 10261.0 |
| UBE2V1 | 10263.0 |
| S100A1 | 10318.0 |
| CCR6 | 10321.0 |
| DEFB136 | 10337.0 |
| TBC1D10C | 10352.0 |
| ITK | 10356.0 |
| HRAS | 10358.0 |
| A1BG | 10369.0 |
| BPIFB6 | 10425.0 |
| SIGLEC14 | 10426.0 |
| C9 | 10502.0 |
| ICAM3 | 10532.0 |
| APOB | 10547.0 |
| IFNA5 | 10573.0 |
| FGG | 10626.0 |
| CD19 | 10838.0 |
| S100A7 | 10858.0 |
| MUC20 | 10878.0 |
| PECAM1 | 10936.0 |
| CD247 | 10977.0 |
| GZMM | 11026.0 |
| SLC15A4 | 11038.0 |
| CFHR2 | 11050.0 |
| CLEC6A | 11060.0 |
| CD3G | 11103.0 |
| DEFB113 | 11116.0 |
| DEFB129 | 11144.0 |
| KLRD1 | 11151.0 |
| LCK | 11167.0 |
| IFNA13 | 11203.0 |
| FCGR3A | 11211.0 |
REACTOME_TRANSLOCATION_OF_SLC2A4_GLUT4_TO_THE_PLASMA_MEMBRANE
| 109 | |
|---|---|
| set | REACTOME_TRANSLOCATION_OF_SLC2A4_GLUT4_TO_THE_PLASMA_MEMBRANE |
| setSize | 71 |
| pANOVA | 0.0294 |
| s.dist | -0.15 |
| p.adjustANOVA | 0.977 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TUBA4A | -9836 |
| TUBB2A | -9625 |
| SFN | -9317 |
| PRKAA2 | -9031 |
| TUBA4B | -8753 |
| RALGAPA2 | -8675 |
| YWHAG | -8443 |
| TUBB4A | -8256 |
| YWHAQ | -8229 |
| VAMP2 | -8045 |
| RAB10 | -7857 |
| SLC2A4 | -7683 |
| YWHAH | -7418 |
| RALA | -7241 |
| TUBB1 | -7168 |
| TUBB8 | -6484 |
| PRKAG1 | -6447 |
| MYO1C | -6272 |
| EXOC7 | -6132 |
| RAB11A | -4966 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TUBA4A | -9836 |
| TUBB2A | -9625 |
| SFN | -9317 |
| PRKAA2 | -9031 |
| TUBA4B | -8753 |
| RALGAPA2 | -8675 |
| YWHAG | -8443 |
| TUBB4A | -8256 |
| YWHAQ | -8229 |
| VAMP2 | -8045 |
| RAB10 | -7857 |
| SLC2A4 | -7683 |
| YWHAH | -7418 |
| RALA | -7241 |
| TUBB1 | -7168 |
| TUBB8 | -6484 |
| PRKAG1 | -6447 |
| MYO1C | -6272 |
| EXOC7 | -6132 |
| RAB11A | -4966 |
| PRKAB2 | -4965 |
| PRKAG2 | -4451 |
| STXBP3 | -4418 |
| YWHAB | -4289 |
| TUBAL3 | -4016 |
| EXOC1 | -3934 |
| PRKAB1 | -3902 |
| TUBA3C | -3458 |
| TUBA1C | -3011 |
| RAB4A | -2964 |
| TBC1D1 | -2761 |
| TBC1D4 | -2225 |
| RAB13 | -2125 |
| TUBA1B | -2095 |
| C2CD5 | -2015 |
| ACTG1 | -1367 |
| ASPSCR1 | -1344 |
| TUBA1A | -920 |
| EXOC2 | -654 |
| SNAP23 | -622 |
| KIF3A | -511 |
| RAC1 | -259 |
| EXOC8 | -257 |
| EXOC6 | -210 |
| KIFAP3 | 72 |
| CALM1 | 217 |
| TUBA8 | 1072 |
| MYO5A | 1630 |
| STX4 | 1881 |
| YWHAE | 2327 |
| TUBB2B | 2471 |
| EXOC4 | 2625 |
| RALGAPB | 2791 |
| RAB8A | 2829 |
| TUBB3 | 2878 |
| EXOC5 | 3001 |
| TUBB6 | 3061 |
| YWHAZ | 3254 |
| RHOQ | 3756 |
| EXOC3 | 3818 |
| RAB14 | 4015 |
| TUBA3E | 4496 |
| AKT1 | 4665 |
| ACTB | 4881 |
| AKT2 | 5123 |
| LNPEP | 6696 |
| TUBB4B | 8016 |
| KIF3B | 9430 |
| TUBA3D | 9444 |
| MYH9 | 10221 |
| PRKAG3 | 10589 |
REACTOME_NCAM1_INTERACTIONS
| 714 | |
|---|---|
| set | REACTOME_NCAM1_INTERACTIONS |
| setSize | 41 |
| pANOVA | 0.0297 |
| s.dist | 0.196 |
| p.adjustANOVA | 0.977 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| COL3A1 | 10666 |
| COL5A2 | 10298 |
| COL9A3 | 10012 |
| GFRA4 | 9589 |
| COL5A1 | 8607 |
| CACNA1S | 8329 |
| PSPN | 7756 |
| COL6A6 | 7452 |
| CACNA1G | 7425 |
| CACNA1I | 7155 |
| COL4A3 | 6632 |
| NRTN | 6334 |
| NCAN | 5727 |
| COL6A3 | 4444 |
| AGRN | 4176 |
| CACNA1D | 4069 |
| COL6A2 | 3880 |
| CACNA1C | 3830 |
| CNTN2 | 3485 |
| GFRA2 | 3375 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| COL3A1 | 10666 |
| COL5A2 | 10298 |
| COL9A3 | 10012 |
| GFRA4 | 9589 |
| COL5A1 | 8607 |
| CACNA1S | 8329 |
| PSPN | 7756 |
| COL6A6 | 7452 |
| CACNA1G | 7425 |
| CACNA1I | 7155 |
| COL4A3 | 6632 |
| NRTN | 6334 |
| NCAN | 5727 |
| COL6A3 | 4444 |
| AGRN | 4176 |
| CACNA1D | 4069 |
| COL6A2 | 3880 |
| CACNA1C | 3830 |
| CNTN2 | 3485 |
| GFRA2 | 3375 |
| CACNB3 | 2990 |
| COL6A5 | 2908 |
| COL2A1 | 2874 |
| CACNB4 | 2684 |
| PRNP | 1423 |
| COL9A1 | 1381 |
| COL4A4 | 1128 |
| COL6A1 | 1016 |
| ST8SIA2 | 962 |
| CACNA1H | 930 |
| CACNB1 | 129 |
| COL9A2 | 82 |
| CACNB2 | -1006 |
| COL4A2 | -2079 |
| ST8SIA4 | -2885 |
| COL4A1 | -4406 |
| GFRA1 | -6358 |
| NCAM1 | -7555 |
| COL5A3 | -8652 |
| GDNF | -9268 |
| ARTN | -10193 |
REACTOME_DEVELOPMENTAL_BIOLOGY
| 76 | |
|---|---|
| set | REACTOME_DEVELOPMENTAL_BIOLOGY |
| setSize | 1115 |
| pANOVA | 0.0315 |
| s.dist | 0.0382 |
| p.adjustANOVA | 0.977 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| KRTAP3-3 | 11229 |
| KRTAP2-3 | 11112 |
| INS | 11091 |
| SPRR2E | 11084 |
| KRTAP4-6 | 11076 |
| KRTAP1-4 | 11021 |
| KRTAP12-4 | 10998 |
| KRT80 | 10940 |
| KRTAP5-1 | 10912 |
| KRTAP9-3 | 10893 |
| SPRR1B | 10883 |
| H2BC15 | 10839 |
| KRTAP5-8 | 10785 |
| ELOB | 10773 |
| KRTAP5-2 | 10724 |
| TCF7 | 10695 |
| COL3A1 | 10666 |
| KRTAP9-9 | 10660 |
| H4C1 | 10651 |
| MYOG | 10608 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| KRTAP3-3 | 11229.0 |
| KRTAP2-3 | 11112.0 |
| INS | 11091.0 |
| SPRR2E | 11084.0 |
| KRTAP4-6 | 11076.0 |
| KRTAP1-4 | 11021.0 |
| KRTAP12-4 | 10998.0 |
| KRT80 | 10940.0 |
| KRTAP5-1 | 10912.0 |
| KRTAP9-3 | 10893.0 |
| SPRR1B | 10883.0 |
| H2BC15 | 10839.0 |
| KRTAP5-8 | 10785.0 |
| ELOB | 10773.0 |
| KRTAP5-2 | 10724.0 |
| TCF7 | 10695.0 |
| COL3A1 | 10666.0 |
| KRTAP9-9 | 10660.0 |
| H4C1 | 10651.0 |
| MYOG | 10608.0 |
| KRTAP10-6 | 10592.0 |
| LCE3A | 10570.0 |
| SPINK9 | 10559.0 |
| RPS15 | 10549.0 |
| KRTAP10-8 | 10528.0 |
| KRTAP5-9 | 10491.0 |
| KRTAP5-4 | 10481.0 |
| EVL | 10439.0 |
| KRTAP21-2 | 10427.0 |
| RPS5 | 10406.0 |
| SPTBN5 | 10403.0 |
| CDSN | 10382.0 |
| HRAS | 10358.0 |
| KRTAP4-4 | 10350.0 |
| KRT15 | 10331.0 |
| KRT4 | 10330.0 |
| KRT85 | 10328.0 |
| KRTAP19-1 | 10319.0 |
| KRT24 | 10314.0 |
| H2AX | 10306.0 |
| COL5A2 | 10298.0 |
| RPL7A | 10253.0 |
| KRTAP21-1 | 10250.0 |
| KLK14 | 10249.0 |
| KRTAP5-11 | 10247.0 |
| DAND5 | 10236.0 |
| MYH9 | 10221.0 |
| H3C1 | 10218.0 |
| KRT37 | 10193.0 |
| KRTAP19-7 | 10190.0 |
| KRT28 | 10139.0 |
| H4C12 | 10113.0 |
| PAX4 | 10107.0 |
| PRKACG | 10084.0 |
| MAG | 10080.0 |
| IVL | 10061.0 |
| COL9A3 | 10012.0 |
| KRT14 | 9979.0 |
| KRT33A | 9970.0 |
| RPS3A | 9887.0 |
| H2AC18 | 9855.5 |
| H2AC19 | 9855.5 |
| UPF3A | 9851.0 |
| KRTAP4-2 | 9849.0 |
| KRT33B | 9839.0 |
| DSCAML1 | 9821.0 |
| NR5A1 | 9803.0 |
| POLR2I | 9779.0 |
| LIPK | 9746.0 |
| PLXNB1 | 9733.0 |
| PCK1 | 9721.0 |
| LEFTY2 | 9710.0 |
| KRTAP13-3 | 9707.0 |
| DSG3 | 9698.0 |
| POLR2E | 9697.0 |
| NFASC | 9696.0 |
| KRT75 | 9692.0 |
| GCK | 9685.0 |
| DSC1 | 9667.0 |
| KRTAP10-2 | 9650.0 |
| KRT35 | 9613.0 |
| MAPK3 | 9611.0 |
| RPL14 | 9602.0 |
| GFRA4 | 9589.0 |
| KRTAP20-2 | 9569.0 |
| RHOB | 9538.0 |
| PCGF2 | 9528.0 |
| KRT13 | 9509.0 |
| KRT71 | 9470.0 |
| TUBA3D | 9444.0 |
| KRTAP10-7 | 9414.0 |
| LCE1B | 9399.0 |
| MED18 | 9387.0 |
| FGFR1 | 9377.0 |
| PSMB11 | 9358.0 |
| LIPJ | 9346.0 |
| KRTAP17-1 | 9321.0 |
| MED22 | 9306.0 |
| POLR2A | 9239.0 |
| DSG4 | 9214.0 |
| KRTAP1-1 | 9193.0 |
| KRTAP12-3 | 9157.0 |
| KRTAP10-9 | 9115.0 |
| H2AC8 | 9082.0 |
| PSME1 | 9064.0 |
| KRT32 | 9030.0 |
| H4C8 | 9029.0 |
| RPL39L | 9028.0 |
| KRT23 | 8973.0 |
| LIPN | 8935.0 |
| EPHB1 | 8928.0 |
| NCOA6 | 8916.0 |
| TEAD2 | 8910.0 |
| SPINK5 | 8908.0 |
| RPL13A | 8897.5 |
| LEFTY1 | 8896.0 |
| UNC5B | 8821.0 |
| CASP14 | 8765.0 |
| PSMC6 | 8742.0 |
| POLR2J | 8735.0 |
| PLXNA2 | 8711.0 |
| RPL29 | 8692.0 |
| KRTAP4-11 | 8680.0 |
| ARHGAP39 | 8638.0 |
| KRT27 | 8637.0 |
| SCN5A | 8626.0 |
| PSMC4 | 8618.0 |
| ARPC3 | 8616.0 |
| COL5A1 | 8607.0 |
| KCNQ2 | 8606.0 |
| EIF4A3 | 8599.0 |
| H3-3A | 8563.0 |
| E2F1 | 8530.0 |
| MEF2B | 8519.0 |
| RPL21 | 8515.0 |
| LGI4 | 8493.0 |
| RPL17 | 8484.0 |
| KRT36 | 8449.0 |
| SRGAP3 | 8447.0 |
| PSMB10 | 8440.0 |
| JUN | 8417.0 |
| PTPRC | 8415.0 |
| KRT6C | 8414.0 |
| PKP3 | 8407.0 |
| SPRR2F | 8406.0 |
| H2AC4 | 8340.0 |
| SCN4A | 8332.0 |
| CACNA1S | 8329.0 |
| NTN3 | 8294.0 |
| ARPC1B | 8246.0 |
| PPL | 8227.0 |
| UNC5A | 8224.0 |
| LYPLA2 | 8194.0 |
| WNT4 | 8188.0 |
| ACTR2 | 8183.0 |
| KIF4B | 8178.0 |
| GPC1 | 8168.0 |
| POLR2D | 8160.0 |
| KRTAP2-1 | 8127.0 |
| RPS16 | 8126.0 |
| SPRR2D | 8090.0 |
| RPL28 | 8059.0 |
| ZNF467 | 8048.0 |
| H4C13 | 8033.0 |
| KRT81 | 8021.0 |
| TUBB4B | 8016.0 |
| FRS2 | 8008.0 |
| FARP2 | 8004.0 |
| MED17 | 8000.0 |
| KRT26 | 7983.0 |
| RPL3 | 7952.0 |
| SMARCA4 | 7925.0 |
| PSENEN | 7924.0 |
| H3C10 | 7891.0 |
| AP2A2 | 7870.0 |
| CCNC | 7823.0 |
| MED16 | 7810.0 |
| KRTAP21-3 | 7805.0 |
| CFL1 | 7796.0 |
| KRTAP19-6 | 7791.0 |
| PSPN | 7756.0 |
| PAK4 | 7754.0 |
| KRTAP4-8 | 7718.0 |
| KRT31 | 7716.0 |
| RARG | 7712.0 |
| NAB2 | 7694.0 |
| CLTB | 7598.0 |
| JUP | 7590.0 |
| MAFB | 7572.0 |
| RGMA | 7553.0 |
| PSMD9 | 7540.0 |
| AGAP2 | 7529.0 |
| ZSCAN10 | 7528.0 |
| RPL32 | 7519.0 |
| RPL38 | 7507.0 |
| EFNA4 | 7488.0 |
| COL6A6 | 7452.0 |
| CACNA1G | 7425.0 |
| DNM1 | 7399.0 |
| RPS24 | 7390.0 |
| KRTAP6-2 | 7388.0 |
| PIK3CA | 7340.0 |
| EPHA8 | 7323.0 |
| CD72 | 7319.0 |
| CARM1 | 7250.0 |
| KRT20 | 7244.0 |
| LEF1 | 7240.0 |
| CNOT6 | 7220.0 |
| CNTNAP1 | 7205.0 |
| H4C3 | 7194.0 |
| SRC | 7174.0 |
| HOXA3 | 7164.0 |
| CDH15 | 7157.0 |
| DLL1 | 7156.0 |
| CACNA1I | 7155.0 |
| KRTAP5-5 | 7141.0 |
| MYL12A | 7131.0 |
| LGI3 | 7128.0 |
| SPTBN2 | 7113.0 |
| EFNA2 | 7106.0 |
| H2BC8 | 7101.0 |
| PAK2 | 7094.0 |
| ACTR3 | 7044.0 |
| KRTAP1-3 | 7038.0 |
| KRT38 | 7037.0 |
| RPL6 | 7029.0 |
| EPHB6 | 7010.0 |
| MAPK12 | 6983.0 |
| AKAP5 | 6981.0 |
| LAMC1 | 6942.0 |
| KRTAP24-1 | 6938.0 |
| FOXA3 | 6933.0 |
| GSK3B | 6926.0 |
| SCN3A | 6896.0 |
| PSMD2 | 6891.0 |
| LELP1 | 6811.0 |
| RAP1GAP | 6809.0 |
| EGR2 | 6803.0 |
| KRTAP5-7 | 6777.0 |
| RPL19 | 6774.0 |
| MYL12B | 6770.0 |
| RPLP0 | 6748.0 |
| IAPP | 6743.0 |
| PIK3R2 | 6728.0 |
| MED28 | 6726.0 |
| SPRR2G | 6718.0 |
| FABP4 | 6670.0 |
| ARHGEF11 | 6649.0 |
| COL4A3 | 6632.0 |
| KRT7 | 6620.0 |
| FOXO1 | 6576.0 |
| ENAH | 6570.0 |
| PSMB5 | 6566.0 |
| PSMD13 | 6561.0 |
| KRT79 | 6556.0 |
| ARPC1A | 6554.0 |
| SCN9A | 6551.0 |
| SCN4B | 6550.0 |
| GRB2 | 6547.0 |
| TCF3 | 6530.0 |
| PIAS2 | 6526.0 |
| ARPC4 | 6513.0 |
| LDB1 | 6482.0 |
| NRTN | 6334.0 |
| AKT3 | 6314.0 |
| RPL23 | 6309.0 |
| UBC | 6258.0 |
| SDCBP | 6255.0 |
| PAK6 | 6239.0 |
| MIXL1 | 6229.0 |
| RPL41 | 6187.0 |
| SOS2 | 6175.0 |
| CDK5 | 6173.0 |
| SPRR2A | 6152.0 |
| CDK4 | 6142.0 |
| PBX1 | 6108.0 |
| POLR2F | 6105.0 |
| RNPS1 | 6098.0 |
| ITGA5 | 6068.0 |
| ADGRV1 | 6046.0 |
| PTK2 | 6033.0 |
| SLIT1 | 6026.0 |
| KRT16 | 6020.0 |
| NCOA3 | 5983.0 |
| CLASP2 | 5913.0 |
| KRTAP4-3 | 5911.0 |
| MAPK8 | 5891.0 |
| H3-3B | 5879.0 |
| RPS2 | 5848.0 |
| PSME2 | 5834.0 |
| PRKCQ | 5824.0 |
| PLCG1 | 5821.0 |
| CDH4 | 5779.0 |
| KAT2A | 5764.0 |
| NCAN | 5727.0 |
| STX1B | 5721.0 |
| POLR2L | 5720.0 |
| MED23 | 5692.0 |
| KRT5 | 5687.0 |
| KRT73 | 5682.0 |
| HJV | 5660.0 |
| MED19 | 5644.0 |
| PAGR1 | 5634.0 |
| MYO9B | 5611.0 |
| PSMC3 | 5595.0 |
| H2BC6 | 5593.0 |
| SPTB | 5570.0 |
| DSG1 | 5521.0 |
| RPS10 | 5499.0 |
| PIK3CD | 5450.0 |
| ST14 | 5446.0 |
| MAPK1 | 5363.0 |
| KRTAP10-4 | 5322.0 |
| RBBP5 | 5312.0 |
| PCSK6 | 5296.0 |
| SPRR1A | 5274.0 |
| PSEN2 | 5250.0 |
| LIPM | 5210.0 |
| ARHGEF7 | 5202.0 |
| GDF1 | 5131.0 |
| DOK1 | 5126.0 |
| AKT2 | 5123.0 |
| TRPC1 | 5112.0 |
| RPS29 | 5072.0 |
| EPHB2 | 4983.0 |
| TCHH | 4976.0 |
| H3C11 | 4968.0 |
| PSMB4 | 4961.0 |
| NEUROD1 | 4923.0 |
| KRT77 | 4891.0 |
| ACTB | 4881.0 |
| UTRN | 4861.0 |
| NGEF | 4843.0 |
| H2AJ | 4770.0 |
| LCE1F | 4759.0 |
| MED13 | 4730.0 |
| POLR2K | 4721.0 |
| DLG1 | 4703.0 |
| PFN1 | 4680.0 |
| PIP5K1C | 4676.0 |
| EOMES | 4669.0 |
| SCN2B | 4666.0 |
| AKT1 | 4665.0 |
| NEUROG3 | 4648.0 |
| KRT76 | 4625.0 |
| LCE3B | 4544.0 |
| RPL34 | 4525.0 |
| LEP | 4516.0 |
| TUBA3E | 4496.0 |
| KRTAP2-2 | 4447.0 |
| COL6A3 | 4444.0 |
| CDK19 | 4435.0 |
| CREBBP | 4419.0 |
| CCND3 | 4397.0 |
| H4C5 | 4387.0 |
| RPS21 | 4373.0 |
| RHOC | 4354.0 |
| KRT25 | 4352.0 |
| RET | 4349.0 |
| WNT10B | 4310.0 |
| NRAS | 4302.0 |
| KRT74 | 4289.0 |
| KRTAP3-1 | 4275.0 |
| RPL13 | 4260.0 |
| EZR | 4219.0 |
| MSGN1 | 4216.0 |
| DRAP1 | 4178.0 |
| AGRN | 4176.0 |
| CREB1 | 4166.0 |
| PI3 | 4120.0 |
| LCE2B | 4087.0 |
| CACNA1D | 4069.0 |
| RPS7 | 4058.0 |
| MPZ | 4046.0 |
| H4C16 | 4042.0 |
| ITGA9 | 4039.0 |
| ADAM22 | 4025.0 |
| PSMD12 | 4000.0 |
| LCE3E | 3969.0 |
| EFNA1 | 3931.0 |
| CDK8 | 3925.0 |
| RPL15 | 3917.0 |
| NTN4 | 3913.0 |
| COL6A2 | 3880.0 |
| KRTAP5-3 | 3869.0 |
| H2AZ2 | 3863.0 |
| PSMB6 | 3841.0 |
| CACNA1C | 3830.0 |
| RBM8A | 3798.0 |
| TGM1 | 3797.0 |
| RPS23 | 3790.0 |
| NCBP2 | 3776.0 |
| VAV2 | 3739.0 |
| BOC | 3737.0 |
| SHC3 | 3716.0 |
| RPS18 | 3715.0 |
| SEMA4A | 3591.0 |
| HNF4A | 3580.0 |
| RBBP4 | 3578.0 |
| LCE4A | 3574.0 |
| KLK8 | 3510.0 |
| TRIO | 3491.0 |
| CNTN2 | 3485.0 |
| PRKACB | 3483.0 |
| ABL2 | 3461.0 |
| H2BC21 | 3429.0 |
| ZSWIM8 | 3414.0 |
| HSP90AA1 | 3411.0 |
| FYN | 3400.0 |
| H2AC6 | 3381.0 |
| GFRA2 | 3375.0 |
| PSMD11 | 3372.0 |
| MEF2A | 3315.0 |
| CSNK2A1 | 3302.0 |
| DMRT1 | 3299.0 |
| TRPC3 | 3297.0 |
| MAP2K2 | 3218.0 |
| RPS8 | 3175.0 |
| SMAD4 | 3112.0 |
| RPS6 | 3103.0 |
| ANK3 | 3099.0 |
| ELOC | 3091.0 |
| CD36 | 3062.0 |
| TUBB6 | 3061.0 |
| RPS15A | 3032.0 |
| WT1 | 3027.0 |
| ARPC5 | 3014.0 |
| MED31 | 2995.0 |
| CACNB3 | 2990.0 |
| CLTCL1 | 2964.0 |
| EBF1 | 2954.0 |
| COL6A5 | 2908.0 |
| GATA4 | 2906.0 |
| MYH10 | 2880.0 |
| TUBB3 | 2878.0 |
| COL2A1 | 2874.0 |
| PAXIP1 | 2843.0 |
| CXCL12 | 2808.0 |
| KLK12 | 2802.0 |
| TIAM1 | 2795.0 |
| FURIN | 2781.0 |
| RPLP2 | 2771.0 |
| CUL2 | 2762.0 |
| ARPC2 | 2761.0 |
| MYC | 2742.0 |
| CTCF | 2741.0 |
| SHTN1 | 2739.0 |
| MYH11 | 2719.0 |
| WNT1 | 2715.0 |
| CACNB4 | 2684.0 |
| EPHB3 | 2668.0 |
| KRTAP15-1 | 2657.0 |
| TEAD4 | 2653.0 |
| CSNK2B | 2620.0 |
| RPS13 | 2618.0 |
| H2BC1 | 2598.0 |
| NODAL | 2593.0 |
| FLI1 | 2591.0 |
| LCE2C | 2561.0 |
| MED21 | 2547.0 |
| CDK2 | 2531.0 |
| H3C4 | 2525.0 |
| UBB | 2521.0 |
| CDK5R1 | 2482.0 |
| GSPT1 | 2479.0 |
| TUBB2B | 2471.0 |
| NTN1 | 2404.0 |
| AP2S1 | 2392.0 |
| PSMA3 | 2388.0 |
| HOXA2 | 2348.0 |
| ACVR2B | 2306.0 |
| DLL3 | 2299.0 |
| H2AC20 | 2285.0 |
| SEMA3A | 2259.0 |
| PSMD6 | 2217.0 |
| EPHB4 | 2165.0 |
| PRX | 2135.0 |
| GATA2 | 2048.0 |
| MEF2C | 2047.0 |
| ADAM11 | 2030.0 |
| H3C2 | 2029.0 |
| ONECUT1 | 2006.0 |
| PSMD3 | 1999.0 |
| ANK1 | 1976.0 |
| DSP | 1946.0 |
| PSMA6 | 1940.0 |
| KRTAP26-1 | 1914.0 |
| RPS11 | 1907.0 |
| RDX | 1897.0 |
| DLG4 | 1858.0 |
| PTPRA | 1826.0 |
| LIN28A | 1817.0 |
| FGF2 | 1798.0 |
| HOXA1 | 1737.0 |
| KRTAP10-5 | 1723.0 |
| EPAS1 | 1687.0 |
| PSME3 | 1671.0 |
| MAML2 | 1662.0 |
| CEBPD | 1640.0 |
| SCN10A | 1627.0 |
| RPL37A | 1624.0 |
| SPTAN1 | 1620.0 |
| MBP | 1605.0 |
| CAPN1 | 1603.0 |
| SMAD3 | 1584.0 |
| KRTAP19-5 | 1541.0 |
| RPS27L | 1532.0 |
| VAV3 | 1454.0 |
| RHOA | 1452.0 |
| KRTAP2-4 | 1440.0 |
| PRNP | 1423.0 |
| TGS1 | 1410.0 |
| ZNF335 | 1408.0 |
| RPL22L1 | 1385.0 |
| COL9A1 | 1381.0 |
| ROCK1 | 1369.0 |
| H2BC13 | 1357.0 |
| NCBP1 | 1316.0 |
| PLXND1 | 1304.0 |
| KRT19 | 1240.0 |
| PKP1 | 1237.0 |
| RPS6KA4 | 1224.0 |
| ITSN1 | 1222.0 |
| RPS25 | 1220.0 |
| HNF4G | 1199.0 |
| DNM2 | 1175.0 |
| SUZ12 | 1171.0 |
| ACVR1B | 1170.0 |
| DOCK1 | 1169.0 |
| RPL11 | 1165.0 |
| CNTN6 | 1160.0 |
| PLXNA1 | 1152.0 |
| ANGPTL4 | 1147.0 |
| COL4A4 | 1128.0 |
| FLRT3 | 1122.0 |
| TUBA8 | 1072.0 |
| SEMA4D | 1051.0 |
| NCSTN | 1050.0 |
| COL6A1 | 1016.0 |
| RPL18 | 1015.0 |
| ST8SIA2 | 962.0 |
| RXRA | 950.0 |
| RPL8 | 943.0 |
| FGF9 | 942.0 |
| PTPN11 | 936.0 |
| CACNA1H | 930.0 |
| GRB10 | 927.0 |
| MED26 | 903.0 |
| LYN | 889.0 |
| RPL7 | 871.0 |
| RPL5 | 870.0 |
| H3C6 | 864.0 |
| HOXC4 | 853.0 |
| RPL26 | 843.0 |
| KRT8 | 790.0 |
| SPTBN1 | 782.0 |
| MED4 | 774.0 |
| USP33 | 771.0 |
| SOS1 | 754.0 |
| NCOA1 | 748.0 |
| SEM1 | 725.0 |
| PKP4 | 716.0 |
| SCN1B | 714.0 |
| SEMA7A | 695.0 |
| THRAP3 | 679.0 |
| RBPJ | 675.0 |
| TEAD1 | 674.0 |
| MEF2D | 642.0 |
| WASL | 627.0 |
| APH1B | 601.0 |
| RPL18A | 589.0 |
| YAP1 | 583.0 |
| TREM2 | 579.0 |
| MED10 | 566.0 |
| PIK3CB | 564.0 |
| PSMD5 | 562.0 |
| TBL1XR1 | 549.0 |
| GRIN1 | 533.0 |
| SMARCD3 | 526.0 |
| EPHA2 | 517.0 |
| PITPNA | 515.0 |
| H2BC4 | 514.0 |
| SALL4 | 452.0 |
| DOK5 | 446.0 |
| PSMC5 | 416.0 |
| VASP | 322.0 |
| MAGOHB | 308.0 |
| SEMA6D | 294.0 |
| PML | 205.0 |
| H4C2 | 199.0 |
| SDC2 | 192.0 |
| MYF5 | 189.0 |
| KRT2 | 156.0 |
| FOXH1 | 140.0 |
| CACNB1 | 129.0 |
| TCF4 | 103.0 |
| HOXD3 | 96.0 |
| COL9A2 | 82.0 |
| PIK3R3 | 32.0 |
| RPL27A | -4.0 |
| ACVR1C | -7.0 |
| ITGA1 | -10.0 |
| RPL35 | -15.0 |
| TRPC4 | -20.0 |
| EPHA1 | -26.0 |
| SLIT2 | -70.0 |
| KLK5 | -100.0 |
| UNC5D | -114.0 |
| PSMA7 | -126.0 |
| FAU | -133.0 |
| MAPK14 | -206.0 |
| SCN7A | -211.0 |
| NUMB | -215.0 |
| EPHA4 | -230.0 |
| NFKB1 | -235.0 |
| RPL35A | -243.0 |
| RAC1 | -259.0 |
| KRTAP19-2 | -309.0 |
| GAB1 | -322.0 |
| RRAS | -342.0 |
| CHL1 | -371.0 |
| POLR2B | -374.0 |
| RPL4 | -382.0 |
| GIT1 | -385.0 |
| RPL36 | -386.0 |
| H2BC5 | -395.0 |
| PSMF1 | -417.0 |
| TBX6 | -423.0 |
| NELL2 | -457.0 |
| CACNG3 | -469.0 |
| HES1 | -490.0 |
| ABLIM2 | -500.0 |
| PSMD1 | -503.0 |
| HSPA8 | -515.0 |
| CBFB | -545.0 |
| RPS27A | -595.0 |
| ROBO2 | -617.0 |
| ERBB2 | -633.0 |
| LCE1A | -635.0 |
| KRT86 | -638.0 |
| HDAC3 | -642.0 |
| SCN2A | -651.0 |
| DSG2 | -663.0 |
| KRTAP4-5 | -690.0 |
| SREBF2 | -693.0 |
| DPYSL4 | -715.0 |
| NCOA2 | -729.0 |
| IRS2 | -733.0 |
| CYP51A1 | -747.0 |
| CACNG2 | -750.0 |
| SLIT3 | -781.0 |
| EPHA3 | -800.0 |
| KRTAP3-2 | -810.0 |
| LCE1E | -821.0 |
| IHH | -826.0 |
| HNF1B | -842.0 |
| PSMD7 | -880.0 |
| PSMC1 | -885.0 |
| TUBA1A | -920.0 |
| SLC2A2 | -926.0 |
| KRT12 | -930.0 |
| RPL10A | -940.0 |
| ABLIM1 | -951.0 |
| KAZN | -992.0 |
| CXCR4 | -995.0 |
| TLN1 | -1000.0 |
| CACNB2 | -1006.0 |
| RPS20 | -1012.0 |
| ROBO1 | -1097.0 |
| H4C4 | -1138.0 |
| H3C8 | -1150.0 |
| NRCAM | -1164.0 |
| PPARG | -1170.0 |
| ITGA2 | -1233.0 |
| MED15 | -1256.0 |
| INSM1 | -1306.0 |
| ARHGEF12 | -1322.0 |
| KRTAP6-1 | -1358.0 |
| ACTG1 | -1367.0 |
| EFNA3 | -1374.0 |
| YES1 | -1376.0 |
| STAT3 | -1377.0 |
| HIF3A | -1378.0 |
| KCNQ3 | -1383.0 |
| RELA | -1401.0 |
| CDC42 | -1417.0 |
| NCOR1 | -1450.0 |
| EVPL | -1522.0 |
| WDR5 | -1527.0 |
| MED20 | -1544.0 |
| MAFA | -1545.0 |
| PSMD8 | -1553.0 |
| PKLR | -1635.0 |
| PSMA1 | -1674.0 |
| CLASP1 | -1686.0 |
| PRKCA | -1711.0 |
| TRPC7 | -1712.0 |
| CEBPB | -1713.0 |
| WNT3A | -1740.0 |
| PSMB8 | -1750.0 |
| MAPK11 | -1759.0 |
| RPL9 | -1760.0 |
| SEMA3E | -1767.0 |
| PSMA8 | -1797.0 |
| CNOT9 | -1845.0 |
| KRTAP10-11 | -1881.0 |
| CLDN7 | -1905.0 |
| WWTR1 | -1924.0 |
| AP2A1 | -1926.0 |
| CHD9 | -1949.0 |
| ITGB1 | -1954.0 |
| LCE2A | -1962.0 |
| GAP43 | -1990.0 |
| NR5A2 | -2003.0 |
| PKNOX1 | -2006.0 |
| SCN1A | -2069.0 |
| COL4A2 | -2079.0 |
| FOXO3 | -2087.0 |
| TUBA1B | -2095.0 |
| PRDM14 | -2120.0 |
| SMAD2 | -2141.0 |
| TGFB1 | -2154.0 |
| CDH1 | -2180.0 |
| TGM5 | -2211.0 |
| RGMB | -2215.0 |
| CACNG4 | -2261.0 |
| EIF4G1 | -2268.0 |
| KRTAP12-2 | -2333.0 |
| NCK2 | -2334.0 |
| PLXNC1 | -2346.0 |
| CTNNA1 | -2357.0 |
| CSNK2A2 | -2365.0 |
| CASC3 | -2368.0 |
| CTNNA2 | -2369.0 |
| ITGB3 | -2419.0 |
| KMT2D | -2444.0 |
| SOX10 | -2451.0 |
| KALRN | -2498.0 |
| MAML3 | -2505.0 |
| MYL6 | -2531.0 |
| KRTAP10-3 | -2551.0 |
| HOXA4 | -2556.0 |
| LCE1C | -2561.0 |
| MAPK7 | -2580.0 |
| PAK1 | -2647.0 |
| DAG1 | -2660.0 |
| LHX3 | -2675.0 |
| PLXNA4 | -2700.0 |
| UBA52 | -2703.0 |
| SCN8A | -2713.0 |
| PSMB9 | -2790.0 |
| SNW1 | -2793.0 |
| PSMA2 | -2839.0 |
| PSEN1 | -2862.0 |
| EP300 | -2871.0 |
| RPL24 | -2882.0 |
| ST8SIA4 | -2885.0 |
| MED27 | -2886.0 |
| MED11 | -2893.0 |
| NOTCH1 | -2899.0 |
| KRT72 | -2905.0 |
| RPL31 | -2919.0 |
| ITGAV | -2938.0 |
| RPS6KA2 | -2953.0 |
| KRTAP8-1 | -2982.0 |
| PSMA5 | -2988.0 |
| TUBA1C | -3011.0 |
| PRSS8 | -3016.0 |
| KAT2B | -3041.0 |
| NCK1 | -3078.0 |
| POU5F1 | -3092.0 |
| SPTA1 | -3093.0 |
| KRTAP29-1 | -3096.0 |
| H2BC3 | -3155.0 |
| H2BC17 | -3157.0 |
| TRPC6 | -3162.0 |
| RPL22 | -3180.0 |
| FOXP1 | -3182.0 |
| ARHGEF28 | -3200.0 |
| SCD5 | -3214.0 |
| MSI1 | -3215.0 |
| CDKN1A | -3222.0 |
| LAMA1 | -3232.0 |
| PSMA4 | -3236.0 |
| CELA2A | -3244.0 |
| SPRR3 | -3302.0 |
| BNIP2 | -3308.0 |
| CAP2 | -3327.0 |
| KRT9 | -3332.0 |
| KRT1 | -3356.0 |
| NAB1 | -3392.0 |
| MAP2K6 | -3393.0 |
| KRT82 | -3446.0 |
| TUBA3C | -3458.0 |
| DNM3 | -3467.0 |
| RELN | -3486.0 |
| EGFR | -3498.0 |
| NCOR2 | -3501.0 |
| KRT78 | -3518.0 |
| ALCAM | -3528.0 |
| PSMD14 | -3626.0 |
| PAX6 | -3716.0 |
| PSMB2 | -3722.0 |
| FOXD3 | -3733.0 |
| MYO10 | -3734.0 |
| TCF12 | -3739.0 |
| EZH2 | -3810.0 |
| PSMB1 | -3823.0 |
| TBPL2 | -3825.0 |
| SEMA6A | -3846.0 |
| SRGAP1 | -3892.0 |
| RPL23A | -3917.0 |
| RPS12 | -3918.0 |
| CLTC | -3933.0 |
| SPTBN4 | -3936.0 |
| MED13L | -3946.0 |
| LAMA2 | -3992.0 |
| NRP2 | -3993.0 |
| PSMD4 | -3996.0 |
| TUBAL3 | -4016.0 |
| H2AZ1 | -4030.0 |
| ONECUT3 | -4050.0 |
| EFNB2 | -4077.0 |
| KRTAP19-8 | -4085.0 |
| RPL30 | -4087.0 |
| SEMA5A | -4097.0 |
| KLF4 | -4099.0 |
| ABLIM3 | -4115.0 |
| PFN2 | -4191.0 |
| PPP3CB | -4219.0 |
| EED | -4238.0 |
| RARA | -4254.0 |
| MET | -4280.0 |
| TFDP2 | -4288.0 |
| LHX9 | -4298.0 |
| HOXB1 | -4315.0 |
| RARB | -4341.0 |
| DHH | -4379.0 |
| COL4A1 | -4406.0 |
| H2BC12 | -4430.0 |
| RPL37 | -4473.0 |
| KRTAP4-1 | -4504.0 |
| EPHA6 | -4530.0 |
| ADGRG6 | -4555.0 |
| H3C3 | -4580.0 |
| TRIM33 | -4585.0 |
| KRTAP9-4 | -4592.0 |
| TBXT | -4622.0 |
| ABL1 | -4623.0 |
| CRMP1 | -4624.0 |
| LHX4 | -4626.0 |
| H3C12 | -4627.0 |
| KRTAP9-2 | -4643.0 |
| ITGA10 | -4651.0 |
| KRTAP6-3 | -4665.0 |
| RPL3L | -4674.0 |
| ADIPOQ | -4718.0 |
| GATA6 | -4720.0 |
| KRTAP13-1 | -4748.0 |
| RPS26 | -4749.0 |
| GAB2 | -4782.0 |
| MED8 | -4835.0 |
| KRT83 | -4838.0 |
| GFRA3 | -4852.0 |
| MED24 | -4918.0 |
| RPS19 | -4923.0 |
| H2BC10 | -4928.0 |
| KRT3 | -4938.0 |
| DSCAM | -4956.0 |
| LAMB1 | -4989.0 |
| SIAH1 | -5045.0 |
| PABPC1 | -5073.0 |
| NOTO | -5110.0 |
| RPL36AL | -5111.5 |
| ISL1 | -5117.0 |
| AJUBA | -5130.0 |
| ADAM10 | -5133.0 |
| MAGOH | -5158.0 |
| PSMC2 | -5276.0 |
| NR6A1 | -5278.0 |
| KLF5 | -5321.0 |
| VLDLR | -5363.0 |
| ACVR2A | -5376.0 |
| HSP90AB1 | -5393.0 |
| H2AC7 | -5404.5 |
| H2BC7 | -5404.5 |
| TSC22D1 | -5411.0 |
| MYH14 | -5418.0 |
| CNTN1 | -5434.0 |
| NRP1 | -5464.0 |
| TFDP1 | -5501.0 |
| SREBF1 | -5544.0 |
| CAPNS1 | -5563.0 |
| HOXD4 | -5588.0 |
| EPHA5 | -5608.0 |
| POLR2H | -5613.0 |
| ADAM23 | -5635.0 |
| DCC | -5641.0 |
| FES | -5668.0 |
| STX1A | -5669.0 |
| PMP22 | -5718.0 |
| RPS6KA5 | -5721.0 |
| RPLP1 | -5817.0 |
| ROCK2 | -5834.0 |
| KRTAP10-1 | -5852.0 |
| CTNNB1 | -5911.0 |
| FOXF1 | -5945.0 |
| SOX2 | -5950.0 |
| PERP | -5957.0 |
| DEK | -5974.0 |
| RND1 | -5996.0 |
| MMP9 | -6001.0 |
| MED9 | -6015.0 |
| MED1 | -6019.0 |
| ARHGAP35 | -6035.0 |
| HDAC2 | -6075.0 |
| RBX1 | -6081.0 |
| GRIN2B | -6096.0 |
| EFNA5 | -6100.0 |
| RASA1 | -6106.0 |
| KRTAP22-1 | -6158.0 |
| KMT2C | -6186.0 |
| KRT10 | -6217.0 |
| ROBO3 | -6227.0 |
| DPYSL2 | -6255.0 |
| HOXB3 | -6281.0 |
| MYOD1 | -6324.0 |
| DPYSL3 | -6331.0 |
| RUNX1 | -6335.0 |
| GFRA1 | -6358.0 |
| POU3F1 | -6367.0 |
| KRTAP19-3 | -6391.0 |
| SH3GL2 | -6412.0 |
| SCN3B | -6439.0 |
| ZFPM2 | -6476.0 |
| TUBB8 | -6484.0 |
| RPS27 | -6538.0 |
| RANBP9 | -6547.0 |
| CDON | -6550.0 |
| MAPK13 | -6622.0 |
| MAP2K1 | -6659.0 |
| PAK5 | -6678.0 |
| CDH2 | -6689.0 |
| H2BC9 | -6699.5 |
| H3C7 | -6699.5 |
| PSMB3 | -6733.0 |
| RPS3 | -6752.0 |
| SCN11A | -6764.0 |
| AP2M1 | -6816.0 |
| PRKAR2A | -6828.0 |
| SOX9 | -6862.0 |
| MED30 | -6910.0 |
| ITGA2B | -6934.0 |
| LHX2 | -6967.0 |
| PDX1 | -6984.0 |
| ANK2 | -7003.0 |
| KRTAP20-1 | -7011.0 |
| KRTAP23-1 | -7026.0 |
| EPHA10 | -7055.0 |
| EFNB3 | -7066.0 |
| H2BC26 | -7080.0 |
| UPF2 | -7096.0 |
| YY1 | -7114.0 |
| RPS28 | -7116.0 |
| DOK2 | -7157.0 |
| LGI2 | -7161.0 |
| TUBB1 | -7168.0 |
| CLTA | -7178.0 |
| HOXB2 | -7181.0 |
| GFI1 | -7201.0 |
| PPARA | -7234.0 |
| KRTAP1-5 | -7237.0 |
| LCE5A | -7270.0 |
| FGF10 | -7292.0 |
| LIMK1 | -7315.0 |
| APH1A | -7351.0 |
| SIAH2 | -7398.0 |
| PSME4 | -7401.0 |
| KRT39 | -7450.0 |
| LPL | -7517.0 |
| NCAM1 | -7555.0 |
| FAM120B | -7571.0 |
| KLK13 | -7580.0 |
| MED29 | -7587.0 |
| ETF1 | -7606.0 |
| NKX2-2 | -7612.0 |
| KRT34 | -7663.0 |
| SLC2A4 | -7683.0 |
| HELZ2 | -7721.0 |
| DOK6 | -7738.0 |
| TNF | -7743.0 |
| PIK3R1 | -7787.0 |
| KRTAP12-1 | -7822.0 |
| H4C9 | -7897.0 |
| HMGCR | -7915.0 |
| TAL1 | -7948.0 |
| KMT2A | -7965.0 |
| CEBPA | -7967.0 |
| RPS14 | -7976.0 |
| DOK4 | -7984.0 |
| MESP2 | -8011.0 |
| POLR2G | -8023.0 |
| DAB1 | -8034.0 |
| KRTAP27-1 | -8073.0 |
| LCE6A | -8100.0 |
| FLG | -8131.0 |
| FOXL2 | -8149.0 |
| DKK1 | -8178.0 |
| RPL27 | -8212.0 |
| MMP2 | -8214.0 |
| SRGAP2 | -8227.0 |
| MYL9 | -8235.0 |
| H4C11 | -8237.0 |
| TUBB4A | -8256.0 |
| SPINK6 | -8257.0 |
| ZNF638 | -8271.0 |
| MYF6 | -8280.0 |
| DPYSL5 | -8283.0 |
| AMH | -8285.0 |
| RPS9 | -8293.0 |
| UNC5C | -8335.0 |
| CACNG8 | -8355.0 |
| RPL26L1 | -8360.0 |
| PRKACA | -8371.0 |
| RPL12 | -8376.0 |
| RFX6 | -8408.0 |
| KRAS | -8414.0 |
| AP2B1 | -8479.0 |
| RPSA | -8490.0 |
| NKX6-1 | -8537.0 |
| MED6 | -8539.0 |
| HOXD1 | -8560.0 |
| IL6R | -8562.0 |
| KRT6A | -8629.0 |
| PTF1A | -8651.0 |
| COL5A3 | -8652.0 |
| SPAG9 | -8708.0 |
| OCLN | -8721.0 |
| TUBA4B | -8753.0 |
| MED7 | -8764.0 |
| SHC1 | -8777.0 |
| KRT6B | -8791.0 |
| PPARGC1A | -8807.0 |
| KRT18 | -8822.0 |
| CSTA | -8828.0 |
| PDLIM7 | -8846.0 |
| KRT40 | -8907.0 |
| NEO1 | -8909.0 |
| FOXA2 | -8911.0 |
| KRTAP9-6 | -8973.0 |
| H2BC14 | -9012.0 |
| POU3F2 | -9038.0 |
| DSC2 | -9070.0 |
| HHEX | -9165.0 |
| CDX2 | -9198.0 |
| KRT84 | -9248.0 |
| SNAI1 | -9250.0 |
| GRB7 | -9258.0 |
| GDNF | -9268.0 |
| H4C6 | -9274.0 |
| RPTN | -9276.0 |
| DSC3 | -9286.0 |
| HNF1A | -9353.0 |
| CSF3R | -9354.0 |
| KRTAP19-4 | -9361.0 |
| KRTAP25-1 | -9364.0 |
| LCE3D | -9386.0 |
| SHH | -9391.0 |
| CAP1 | -9392.0 |
| RPS6KA1 | -9417.0 |
| PSMB7 | -9461.0 |
| HOXB4 | -9474.0 |
| POLR2C | -9491.0 |
| LGI1 | -9528.0 |
| H2AC14 | -9598.0 |
| RPL10L | -9603.0 |
| EPHA7 | -9610.0 |
| PLIN1 | -9623.0 |
| TUBB2A | -9625.0 |
| MAML1 | -9639.0 |
| BMP4 | -9647.0 |
| SALL1 | -9665.0 |
| FOXA1 | -9671.0 |
| ADIRF | -9696.0 |
| KRTAP13-4 | -9710.0 |
| NOG | -9713.0 |
| MED25 | -9714.0 |
| MYB | -9728.0 |
| H2BC11 | -9738.0 |
| NR2F2 | -9776.0 |
| LCE2D | -9792.0 |
| MEIS1 | -9826.0 |
| TUBA4A | -9836.0 |
| NANOG | -9840.0 |
| TYROBP | -9897.0 |
| ASH2L | -9910.0 |
| KRTAP11-1 | -9930.0 |
| KRTAP4-7 | -9948.0 |
| KRTAP10-12 | -9991.0 |
| KRTAP5-6 | -10131.0 |
| KRTAP10-10 | -10142.0 |
| CER1 | -10160.0 |
| GSC | -10178.0 |
| PKP2 | -10181.0 |
| LIMK2 | -10189.0 |
| ARTN | -10193.0 |
| KRTAP13-2 | -10230.0 |
| SPI1 | -10236.0 |
| KRTAP9-1 | -10324.0 |
| PTGDS | -10431.0 |
| KRTAP5-10 | -10472.5 |
| DPPA4 | -10508.0 |
| KRTAP16-1 | -10654.0 |
| CEBPE | -10660.0 |
| KRT17 | -10723.0 |
REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_EARLY_PANCREATIC_PRECURSOR_CELLS
| 422 | |
|---|---|
| set | REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_EARLY_PANCREATIC_PRECURSOR_CELLS |
| setSize | 8 |
| pANOVA | 0.0321 |
| s.dist | -0.437 |
| p.adjustANOVA | 0.977 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| PTF1A | -8651 |
| NKX6-1 | -8537 |
| FGF10 | -7292 |
| PDX1 | -6984 |
| ONECUT3 | -4050 |
| NR5A2 | -2003 |
| HNF1B | -842 |
| ONECUT1 | 2006 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| PTF1A | -8651 |
| NKX6-1 | -8537 |
| FGF10 | -7292 |
| PDX1 | -6984 |
| ONECUT3 | -4050 |
| NR5A2 | -2003 |
| HNF1B | -842 |
| ONECUT1 | 2006 |
REACTOME_BIOSYNTHESIS_OF_SPECIALIZED_PRORESOLVING_MEDIATORS_SPMS
| 1396 | |
|---|---|
| set | REACTOME_BIOSYNTHESIS_OF_SPECIALIZED_PRORESOLVING_MEDIATORS_SPMS |
| setSize | 19 |
| pANOVA | 0.0328 |
| s.dist | -0.283 |
| p.adjustANOVA | 0.977 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| ALOX5AP | -10385 |
| ALOX15 | -10084 |
| CYP2C8 | -10022 |
| PTGS2 | -9942 |
| LTC4S | -9412 |
| CYP1A2 | -8756 |
| HPGD | -6556 |
| LTA4H | -6130 |
| ALOX5 | -4854 |
| PTGR1 | -3370 |
| ALOX12 | -3287 |
| GPX4 | 578 |
| CYP2D6 | 760 |
| CYP2E1 | 1010 |
| CYP1A1 | 1830 |
| CYP2C9 | 4554 |
| EPHX2 | 5696 |
| GSTM4 | 6527 |
| CYP3A4 | 7839 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ALOX5AP | -10385 |
| ALOX15 | -10084 |
| CYP2C8 | -10022 |
| PTGS2 | -9942 |
| LTC4S | -9412 |
| CYP1A2 | -8756 |
| HPGD | -6556 |
| LTA4H | -6130 |
| ALOX5 | -4854 |
| PTGR1 | -3370 |
| ALOX12 | -3287 |
| GPX4 | 578 |
| CYP2D6 | 760 |
| CYP2E1 | 1010 |
| CYP1A1 | 1830 |
| CYP2C9 | 4554 |
| EPHX2 | 5696 |
| GSTM4 | 6527 |
| CYP3A4 | 7839 |
REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM
| 338 | |
|---|---|
| set | REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM |
| setSize | 45 |
| pANOVA | 0.0331 |
| s.dist | 0.184 |
| p.adjustANOVA | 0.977 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| SLC10A2 | 10604 |
| CYP8B1 | 10574 |
| AKR1C1 | 10063 |
| SLC51B | 10051 |
| SLC27A2 | 9658 |
| STARD5 | 9415 |
| OSBPL6 | 9245 |
| ALB | 8929 |
| OSBP | 8319 |
| SLCO1B1 | 8148 |
| FABP6 | 7887 |
| NR1H4 | 7603 |
| CYP46A1 | 7159 |
| SLC27A5 | 6085 |
| SLCO1B3 | 5587 |
| AKR1C4 | 5346 |
| ACOX2 | 4473 |
| PTGIS | 4420 |
| OSBPL7 | 3597 |
| SCP2 | 3236 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SLC10A2 | 10604 |
| CYP8B1 | 10574 |
| AKR1C1 | 10063 |
| SLC51B | 10051 |
| SLC27A2 | 9658 |
| STARD5 | 9415 |
| OSBPL6 | 9245 |
| ALB | 8929 |
| OSBP | 8319 |
| SLCO1B1 | 8148 |
| FABP6 | 7887 |
| NR1H4 | 7603 |
| CYP46A1 | 7159 |
| SLC27A5 | 6085 |
| SLCO1B3 | 5587 |
| AKR1C4 | 5346 |
| ACOX2 | 4473 |
| PTGIS | 4420 |
| OSBPL7 | 3597 |
| SCP2 | 3236 |
| AMACR | 3174 |
| ACOT8 | 2286 |
| AKR1C2 | 1987 |
| AKR1D1 | 1772 |
| OSBPL2 | 1616 |
| HSD3B7 | 1187 |
| RXRA | 950 |
| NCOA1 | 748 |
| CYP27A1 | 362 |
| OSBPL3 | 172 |
| OSBPL1A | -185 |
| NCOA2 | -729 |
| HSD17B4 | -777 |
| SLCO1A2 | -1027 |
| ABCB11 | -1720 |
| SLC51A | -2137 |
| OSBPL9 | -2422 |
| BAAT | -2567 |
| CYP7A1 | -3357 |
| AKR1C3 | -4506 |
| ABCC3 | -4568 |
| CYP39A1 | -8301 |
| CH25H | -9125 |
| CYP7B1 | -9944 |
| SLC10A1 | -10498 |
Here is the session info with all the versions of packages used.
sessionInfo()## R version 4.3.2 (2023-10-31)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.3 LTS
##
## Matrix products: default
## BLAS: /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so; LAPACK version 3.10.0
##
## locale:
## [1] LC_CTYPE=en_US.UTF-8 LC_NUMERIC=C
## [3] LC_TIME=en_US.UTF-8 LC_COLLATE=en_US.UTF-8
## [5] LC_MONETARY=en_US.UTF-8 LC_MESSAGES=en_US.UTF-8
## [7] LC_PAPER=en_US.UTF-8 LC_NAME=C
## [9] LC_ADDRESS=C LC_TELEPHONE=C
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C
##
## time zone: Etc/UTC
## tzcode source: system (glibc)
##
## attached base packages:
## [1] parallel stats4 stats graphics grDevices utils datasets
## [8] methods base
##
## other attached packages:
## [1] pkgload_1.3.3
## [2] GGally_2.2.0
## [3] ggplot2_3.4.4
## [4] reshape2_1.4.4
## [5] gtools_3.9.5
## [6] tibble_3.2.1
## [7] dplyr_1.1.4
## [8] echarts4r_0.4.5
## [9] png_0.1-8
## [10] gridExtra_2.3
## [11] missMethyl_1.36.0
## [12] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.1
## [13] beeswarm_0.4.0
## [14] kableExtra_1.3.4
## [15] gplots_3.1.3
## [16] mitch_1.15.0
## [17] tictoc_1.2
## [18] HGNChelper_0.8.1
## [19] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [20] IlluminaHumanMethylation450kmanifest_0.4.0
## [21] minfi_1.48.0
## [22] bumphunter_1.44.0
## [23] locfit_1.5-9.8
## [24] iterators_1.0.14
## [25] foreach_1.5.2
## [26] Biostrings_2.70.1
## [27] XVector_0.42.0
## [28] SummarizedExperiment_1.32.0
## [29] Biobase_2.62.0
## [30] MatrixGenerics_1.14.0
## [31] matrixStats_1.2.0
## [32] GenomicRanges_1.54.1
## [33] GenomeInfoDb_1.38.2
## [34] IRanges_2.36.0
## [35] S4Vectors_0.40.2
## [36] BiocGenerics_0.48.1
## [37] eulerr_7.0.0
## [38] limma_3.58.1
##
## loaded via a namespace (and not attached):
## [1] splines_4.3.2 later_1.3.2
## [3] BiocIO_1.12.0 bitops_1.0-7
## [5] filelock_1.0.3 preprocessCore_1.64.0
## [7] XML_3.99-0.16 lifecycle_1.0.4
## [9] lattice_0.22-5 MASS_7.3-60
## [11] base64_2.0.1 scrime_1.3.5
## [13] magrittr_2.0.3 sass_0.4.8
## [15] rmarkdown_2.25 jquerylib_0.1.4
## [17] yaml_2.3.8 httpuv_1.6.13
## [19] doRNG_1.8.6 askpass_1.2.0
## [21] DBI_1.1.3 RColorBrewer_1.1-3
## [23] abind_1.4-5 zlibbioc_1.48.0
## [25] rvest_1.0.3 quadprog_1.5-8
## [27] purrr_1.0.2 RCurl_1.98-1.13
## [29] rappdirs_0.3.3 GenomeInfoDbData_1.2.11
## [31] genefilter_1.84.0 annotate_1.80.0
## [33] svglite_2.1.3 DelayedMatrixStats_1.24.0
## [35] codetools_0.2-19 DelayedArray_0.28.0
## [37] xml2_1.3.6 tidyselect_1.2.0
## [39] beanplot_1.3.1 BiocFileCache_2.10.1
## [41] webshot_0.5.5 illuminaio_0.44.0
## [43] GenomicAlignments_1.38.0 jsonlite_1.8.8
## [45] multtest_2.58.0 ellipsis_0.3.2
## [47] survival_3.5-7 systemfonts_1.0.5
## [49] tools_4.3.2 progress_1.2.3
## [51] Rcpp_1.0.11 glue_1.6.2
## [53] SparseArray_1.2.2 xfun_0.41
## [55] HDF5Array_1.30.0 withr_2.5.2
## [57] fastmap_1.1.1 rhdf5filters_1.14.1
## [59] fansi_1.0.6 openssl_2.1.1
## [61] caTools_1.18.2 digest_0.6.33
## [63] R6_2.5.1 mime_0.12
## [65] colorspace_2.1-0 biomaRt_2.58.0
## [67] RSQLite_2.3.4 utf8_1.2.4
## [69] tidyr_1.3.0 generics_0.1.3
## [71] data.table_1.14.10 rtracklayer_1.62.0
## [73] prettyunits_1.2.0 httr_1.4.7
## [75] htmlwidgets_1.6.4 S4Arrays_1.2.0
## [77] ggstats_0.5.1 pkgconfig_2.0.3
## [79] gtable_0.3.4 blob_1.2.4
## [81] siggenes_1.76.0 htmltools_0.5.7
## [83] scales_1.3.0 rstudioapi_0.15.0
## [85] knitr_1.45 tzdb_0.4.0
## [87] rjson_0.2.21 nlme_3.1-163
## [89] curl_5.2.0 org.Hs.eg.db_3.18.0
## [91] cachem_1.0.8 rhdf5_2.46.1
## [93] stringr_1.5.1 KernSmooth_2.23-22
## [95] AnnotationDbi_1.64.1 restfulr_0.0.15
## [97] GEOquery_2.70.0 pillar_1.9.0
## [99] grid_4.3.2 reshape_0.8.9
## [101] vctrs_0.6.5 promises_1.2.1
## [103] dbplyr_2.4.0 xtable_1.8-4
## [105] evaluate_0.23 readr_2.1.4
## [107] GenomicFeatures_1.54.1 cli_3.6.2
## [109] compiler_4.3.2 Rsamtools_2.18.0
## [111] rlang_1.1.2 crayon_1.5.2
## [113] rngtools_1.5.2 nor1mix_1.3-2
## [115] mclust_6.0.1 plyr_1.8.9
## [117] stringi_1.8.3 viridisLite_0.4.2
## [119] BiocParallel_1.36.0 munsell_0.5.0
## [121] Matrix_1.6-1.1 hms_1.1.3
## [123] sparseMatrixStats_1.14.0 bit64_4.0.5
## [125] Rhdf5lib_1.24.1 KEGGREST_1.42.0
## [127] statmod_1.5.0 shiny_1.8.0
## [129] highr_0.10 memoise_2.0.1
## [131] bslib_0.6.1 bit_4.0.5END of report