Mitch Report

date generated: 2024-01-18

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch

	x
A1BG	0.0006228
A1BG-AS1	0.0006301
A1CF	-0.0013322
A2M	-0.0010101
A2M-AS1	-0.0000065
A2ML1	-0.0008100

Here are some metrics about the input data profile:

Profiling data metrics

	Profile metrics
num_genesets	1654
num_genes_in_profile	22007
duplicated_genes_present	0
num_profile_genes_in_sets	10383
num_profile_genes_not_in_sets	11624

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets: c2.cp.reactome.v2023.1.Hs.symbols.gmt

Gene set metrics

	Gene sets metrics
num_genesets	1654
num_genesets_excluded	365
num_genesets_included	1289

Differential pathway expression

Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

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## in kable. kableExtra can customize either HTML or LaTeX outputs. See
## https://haozhu233.github.io/kableExtra/ for details.

set	setSize	pANOVA	s.dist	p.adjustANOVA
REACTOME SENSORY PERCEPTION	555	6.28e-35	-0.3060	1.03e-31
REACTOME OLFACTORY SIGNALING PATHWAY	348	3.07e-29	-0.3500	2.52e-26
REACTOME RNA POLYMERASE II TRANSCRIPTION	1336	1.86e-24	0.1660	1.02e-21
REACTOME CELLULAR RESPONSES TO STIMULI	779	1.87e-16	0.1730	7.69e-14
REACTOME KERATINIZATION	210	3.45e-14	-0.3030	1.13e-11
REACTOME CELL CYCLE	666	2.10e-10	0.1440	5.74e-08
REACTOME METABOLISM OF RNA	675	4.02e-10	0.1410	9.43e-08
REACTOME CELL CYCLE MITOTIC	539	1.11e-09	0.1530	2.28e-07
REACTOME FORMATION OF THE CORNIFIED ENVELOPE	125	1.34e-09	-0.3140	2.44e-07
REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	134	3.08e-09	-0.2960	5.05e-07
REACTOME EXTRACELLULAR MATRIX ORGANIZATION	291	3.63e-09	-0.2010	5.42e-07
REACTOME INFECTIOUS DISEASE	910	7.81e-09	0.1130	1.07e-06
REACTOME TRANSCRIPTIONAL REGULATION BY TP53	351	1.06e-08	0.1780	1.34e-06
REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS	83	3.32e-08	0.3510	3.89e-06
REACTOME ADAPTIVE IMMUNE SYSTEM	729	7.98e-08	0.1170	8.74e-06
REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP	104	1.13e-07	0.3010	1.15e-05
REACTOME CELLULAR SENESCENCE	189	1.19e-07	0.2230	1.15e-05
REACTOME M PHASE	398	4.53e-07	0.1470	4.13e-05
REACTOME OXIDATIVE STRESS INDUCED SENESCENCE	118	4.88e-07	0.2680	4.22e-05
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION	1356	6.27e-07	0.0806	5.15e-05
REACTOME ASPIRIN ADME	42	7.20e-07	-0.4420	5.63e-05
REACTOME TRANSLATION	278	8.50e-07	0.1720	6.34e-05
REACTOME DNA REPAIR	321	1.04e-06	0.1590	7.13e-05
REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION	62	1.04e-06	0.3590	7.13e-05
REACTOME DNA REPLICATION PRE INITIATION	150	1.48e-06	0.2280	9.71e-05
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION	361	1.57e-06	0.1470	9.91e-05
REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS	113	1.97e-06	0.2590	1.20e-04
REACTOME DNA REPLICATION	178	2.40e-06	0.2050	1.40e-04
REACTOME ECM PROTEOGLYCANS	73	2.48e-06	-0.3190	1.40e-04
REACTOME HDACS DEACETYLATE HISTONES	85	4.36e-06	0.2880	2.38e-04
REACTOME DRUG ADME	103	4.77e-06	-0.2610	2.52e-04
REACTOME HOMOLOGY DIRECTED REPAIR	132	4.92e-06	0.2300	2.52e-04
REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION	68	5.88e-06	0.3180	2.93e-04
REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION	98	6.62e-06	0.2630	3.19e-04
REACTOME COLLAGEN FORMATION	88	7.19e-06	-0.2770	3.30e-04
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION	138	7.24e-06	0.2210	3.30e-04
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1	229	7.57e-06	0.1720	3.36e-04
REACTOME CONDENSATION OF PROPHASE CHROMOSOMES	66	7.95e-06	0.3180	3.43e-04
REACTOME BASE EXCISION REPAIR	87	1.12e-05	0.2720	4.69e-04
REACTOME DNA METHYLATION	58	1.18e-05	0.3330	4.85e-04
REACTOME COLLAGEN DEGRADATION	61	1.24e-05	-0.3230	4.96e-04
REACTOME RNA POLYMERASE I TRANSCRIPTION	102	1.36e-05	0.2490	5.25e-04
REACTOME CHROMOSOME MAINTENANCE	130	1.38e-05	0.2210	5.25e-04
REACTOME DEUBIQUITINATION	260	1.47e-05	0.1560	5.47e-04
REACTOME PRC2 METHYLATES HISTONES AND DNA	65	1.54e-05	0.3100	5.58e-04
REACTOME RHO GTPASE EFFECTORS	305	1.56e-05	0.1440	5.58e-04
REACTOME NEUTROPHIL DEGRANULATION	460	1.75e-05	0.1170	6.13e-04
REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION	84	1.99e-05	0.2690	6.80e-04
REACTOME HCMV INFECTION	152	2.12e-05	0.2000	7.10e-04
REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3	679	2.20e-05	0.0955	7.21e-04

---

Results (complete table)

Click HERE to show results for all gene sets

Complete results

set	setSize	pANOVA	s.dist	p.adjustANOVA
REACTOME SENSORY PERCEPTION	555	6.28e-35	-3.06e-01	1.03e-31
REACTOME OLFACTORY SIGNALING PATHWAY	348	3.07e-29	-3.50e-01	2.52e-26
REACTOME RNA POLYMERASE II TRANSCRIPTION	1336	1.86e-24	1.66e-01	1.02e-21
REACTOME CELLULAR RESPONSES TO STIMULI	779	1.87e-16	1.73e-01	7.69e-14
REACTOME KERATINIZATION	210	3.45e-14	-3.03e-01	1.13e-11
REACTOME CELL CYCLE	666	2.10e-10	1.44e-01	5.74e-08
REACTOME METABOLISM OF RNA	675	4.02e-10	1.41e-01	9.43e-08
REACTOME CELL CYCLE MITOTIC	539	1.11e-09	1.53e-01	2.28e-07
REACTOME FORMATION OF THE CORNIFIED ENVELOPE	125	1.34e-09	-3.14e-01	2.44e-07
REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	134	3.08e-09	-2.96e-01	5.05e-07
REACTOME EXTRACELLULAR MATRIX ORGANIZATION	291	3.63e-09	-2.01e-01	5.42e-07
REACTOME INFECTIOUS DISEASE	910	7.81e-09	1.13e-01	1.07e-06
REACTOME TRANSCRIPTIONAL REGULATION BY TP53	351	1.06e-08	1.78e-01	1.34e-06
REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS	83	3.32e-08	3.51e-01	3.89e-06
REACTOME ADAPTIVE IMMUNE SYSTEM	729	7.98e-08	1.17e-01	8.74e-06
REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP	104	1.13e-07	3.01e-01	1.15e-05
REACTOME CELLULAR SENESCENCE	189	1.19e-07	2.23e-01	1.15e-05
REACTOME M PHASE	398	4.53e-07	1.47e-01	4.13e-05
REACTOME OXIDATIVE STRESS INDUCED SENESCENCE	118	4.88e-07	2.68e-01	4.22e-05
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION	1356	6.27e-07	8.06e-02	5.15e-05
REACTOME ASPIRIN ADME	42	7.20e-07	-4.42e-01	5.63e-05
REACTOME TRANSLATION	278	8.50e-07	1.72e-01	6.34e-05
REACTOME DNA REPAIR	321	1.04e-06	1.59e-01	7.13e-05
REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION	62	1.04e-06	3.59e-01	7.13e-05
REACTOME DNA REPLICATION PRE INITIATION	150	1.48e-06	2.28e-01	9.71e-05
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION	361	1.57e-06	1.47e-01	9.91e-05
REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS	113	1.97e-06	2.59e-01	1.20e-04
REACTOME DNA REPLICATION	178	2.40e-06	2.05e-01	1.40e-04
REACTOME ECM PROTEOGLYCANS	73	2.48e-06	-3.19e-01	1.40e-04
REACTOME HDACS DEACETYLATE HISTONES	85	4.36e-06	2.88e-01	2.38e-04
REACTOME DRUG ADME	103	4.77e-06	-2.61e-01	2.52e-04
REACTOME HOMOLOGY DIRECTED REPAIR	132	4.92e-06	2.30e-01	2.52e-04
REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION	68	5.88e-06	3.18e-01	2.93e-04
REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION	98	6.62e-06	2.63e-01	3.19e-04
REACTOME COLLAGEN FORMATION	88	7.19e-06	-2.77e-01	3.30e-04
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION	138	7.24e-06	2.21e-01	3.30e-04
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1	229	7.57e-06	1.72e-01	3.36e-04
REACTOME CONDENSATION OF PROPHASE CHROMOSOMES	66	7.95e-06	3.18e-01	3.43e-04
REACTOME BASE EXCISION REPAIR	87	1.12e-05	2.72e-01	4.69e-04
REACTOME DNA METHYLATION	58	1.18e-05	3.33e-01	4.85e-04
REACTOME COLLAGEN DEGRADATION	61	1.24e-05	-3.23e-01	4.96e-04
REACTOME RNA POLYMERASE I TRANSCRIPTION	102	1.36e-05	2.49e-01	5.25e-04
REACTOME CHROMOSOME MAINTENANCE	130	1.38e-05	2.21e-01	5.25e-04
REACTOME DEUBIQUITINATION	260	1.47e-05	1.56e-01	5.47e-04
REACTOME PRC2 METHYLATES HISTONES AND DNA	65	1.54e-05	3.10e-01	5.58e-04
REACTOME RHO GTPASE EFFECTORS	305	1.56e-05	1.44e-01	5.58e-04
REACTOME NEUTROPHIL DEGRANULATION	460	1.75e-05	1.17e-01	6.13e-04
REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION	84	1.99e-05	2.69e-01	6.80e-04
REACTOME HCMV INFECTION	152	2.12e-05	2.00e-01	7.10e-04
REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3	679	2.20e-05	9.55e-02	7.21e-04
REACTOME RNA POLYMERASE I PROMOTER ESCAPE	83	2.26e-05	2.69e-01	7.28e-04
REACTOME COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES	65	2.34e-05	-3.03e-01	7.29e-04
REACTOME HATS ACETYLATE HISTONES	129	2.36e-05	2.16e-01	7.29e-04
REACTOME VISUAL PHOTOTRANSDUCTION	93	2.40e-05	-2.53e-01	7.29e-04
REACTOME NEDDYLATION	235	2.44e-05	1.60e-01	7.29e-04
REACTOME G2 M DNA DAMAGE CHECKPOINT	90	2.54e-05	2.57e-01	7.45e-04
REACTOME COLLAGEN CHAIN TRIMERIZATION	42	3.32e-05	-3.70e-01	9.57e-04
REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	296	3.46e-05	1.40e-01	9.80e-04
REACTOME DNA DOUBLE STRAND BREAK REPAIR	162	3.61e-05	1.88e-01	1.00e-03
REACTOME TELOMERE MAINTENANCE	106	3.85e-05	2.31e-01	1.04e-03
REACTOME HCMV EARLY EVENTS	128	3.87e-05	2.11e-01	1.04e-03
REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION	90	4.14e-05	2.50e-01	1.10e-03
REACTOME MITOCHONDRIAL TRANSLATION	93	4.52e-05	2.45e-01	1.16e-03
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	263	4.54e-05	1.46e-01	1.16e-03
REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION	100	5.04e-05	2.35e-01	1.26e-03
REACTOME RHO GTPASES ACTIVATE PKNS	86	5.05e-05	2.53e-01	1.26e-03
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS	121	5.33e-05	2.13e-01	1.31e-03
REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX	85	5.88e-05	2.52e-01	1.41e-03
REACTOME UNFOLDED PROTEIN RESPONSE UPR	88	5.91e-05	2.48e-01	1.41e-03
REACTOME DIGESTION AND ABSORPTION	22	6.01e-05	-4.94e-01	1.41e-03
REACTOME ACTIVATION OF MATRIX METALLOPROTEINASES	30	6.18e-05	-4.23e-01	1.43e-03
REACTOME ESTROGEN DEPENDENT GENE EXPRESSION	140	6.41e-05	1.96e-01	1.46e-03
REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION	60	6.61e-05	2.98e-01	1.49e-03
REACTOME PROSTANOID LIGAND RECEPTORS	9	7.28e-05	7.63e-01	1.62e-03
REACTOME INITIAL TRIGGERING OF COMPLEMENT	21	7.46e-05	-4.99e-01	1.63e-03
REACTOME UB SPECIFIC PROCESSING PROTEASES	187	8.37e-05	1.67e-01	1.79e-03
REACTOME MITOTIC PROPHASE	134	8.39e-05	1.97e-01	1.79e-03
REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS	188	8.61e-05	1.66e-01	1.80e-03
REACTOME CHROMATIN MODIFYING ENZYMES	252	8.66e-05	1.44e-01	1.80e-03
REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3	59	9.98e-05	2.93e-01	2.05e-03
REACTOME COMPLEMENT CASCADE	54	1.02e-04	-3.06e-01	2.06e-03
REACTOME HCMV LATE EVENTS	110	1.16e-04	2.13e-01	2.31e-03
REACTOME DIGESTION	17	1.18e-04	-5.39e-01	2.31e-03
REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS	66	1.18e-04	-2.74e-01	2.31e-03
REACTOME CELL CYCLE CHECKPOINTS	284	1.21e-04	1.33e-01	2.33e-03
REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	66	1.58e-04	2.69e-01	3.02e-03
REACTOME SARS COV INFECTIONS	392	1.95e-04	1.10e-01	3.67e-03
REACTOME REGULATION OF TP53 ACTIVITY	156	1.99e-04	1.73e-01	3.71e-03
REACTOME MEMBRANE TRAFFICKING	603	2.01e-04	8.86e-02	3.71e-03
REACTOME RRNA PROCESSING	192	2.12e-04	1.55e-01	3.87e-03
REACTOME SIGNALING BY NUCLEAR RECEPTORS	283	2.16e-04	1.28e-01	3.89e-03
REACTOME ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES	59	2.27e-04	-2.78e-01	4.04e-03
REACTOME MRNA SPLICING	197	2.35e-04	1.52e-01	4.15e-03
REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS	100	2.64e-04	2.11e-01	4.61e-03
REACTOME DISEASES OF PROGRAMMED CELL DEATH	96	2.71e-04	2.15e-01	4.69e-03
REACTOME NGF STIMULATED TRANSCRIPTION	38	2.76e-04	3.41e-01	4.72e-03
REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE	63	2.91e-04	2.64e-01	4.92e-03
REACTOME PROTEIN UBIQUITINATION	76	3.06e-04	2.39e-01	5.12e-03
REACTOME SARS COV 1 INFECTION	136	3.19e-04	1.79e-01	5.30e-03
REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER	81	3.42e-04	2.30e-01	5.61e-03
REACTOME PRE NOTCH EXPRESSION AND PROCESSING	112	4.06e-04	1.93e-01	6.56e-03
REACTOME SUMOYLATION	179	4.08e-04	1.53e-01	6.56e-03
REACTOME SENSORY PERCEPTION OF TASTE	47	4.14e-04	-2.98e-01	6.60e-03
REACTOME DISEASES OF GLYCOSYLATION	137	4.45e-04	-1.74e-01	7.02e-03
REACTOME PROCESSING OF DNA DOUBLE STRAND BREAK ENDS	93	4.60e-04	2.10e-01	7.19e-03
REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT	222	4.75e-04	1.36e-01	7.36e-03
REACTOME HDR THROUGH HOMOLOGOUS RECOMBINATION HRR	66	5.70e-04	2.45e-01	8.74e-03
REACTOME BASE EXCISION REPAIR AP SITE FORMATION	59	5.75e-04	2.59e-01	8.74e-03
REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE	52	5.88e-04	2.75e-01	8.86e-03
REACTOME ESR MEDIATED SIGNALING	210	5.96e-04	1.37e-01	8.90e-03
REACTOME MEIOTIC RECOMBINATION	80	6.58e-04	2.20e-01	9.73e-03
REACTOME MUSCLE CONTRACTION	197	6.66e-04	-1.41e-01	9.77e-03
REACTOME INNATE IMMUNE SYSTEM	1002	6.90e-04	6.33e-02	1.00e-02
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM	688	7.71e-04	7.52e-02	1.11e-02
REACTOME SIGNALING BY WNT	318	8.25e-04	1.09e-01	1.17e-02
REACTOME ORGANIC ANION TRANSPORT	5	8.30e-04	-8.63e-01	1.17e-02
REACTOME G2 M CHECKPOINTS	162	8.61e-04	1.52e-01	1.21e-02
REACTOME CREATION OF C4 AND C2 ACTIVATORS	14	8.79e-04	-5.13e-01	1.22e-02
REACTOME RMTS METHYLATE HISTONE ARGININES	72	9.40e-04	2.25e-01	1.30e-02
REACTOME GENE SILENCING BY RNA	133	9.59e-04	1.66e-01	1.31e-02
REACTOME INTEGRIN CELL SURFACE INTERACTIONS	83	9.84e-04	-2.09e-01	1.34e-02
REACTOME DAP12 INTERACTIONS	37	1.09e-03	3.10e-01	1.46e-02
REACTOME SIGNALING BY NOTCH	234	1.11e-03	1.24e-01	1.49e-02
REACTOME RAB REGULATION OF TRAFFICKING	110	1.18e-03	1.79e-01	1.56e-02
REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT	236	1.20e-03	-1.22e-01	1.58e-02
REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	59	1.27e-03	2.43e-01	1.65e-02
REACTOME BIOLOGICAL OXIDATIONS	210	1.28e-03	-1.29e-01	1.65e-02
REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT	159	1.29e-03	1.48e-01	1.66e-02
REACTOME E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS	58	1.32e-03	2.44e-01	1.68e-02
REACTOME MET ACTIVATES PTK2 SIGNALING	30	1.34e-03	-3.38e-01	1.69e-02
REACTOME NUCLEOTIDE EXCISION REPAIR	107	1.35e-03	1.79e-01	1.69e-02
REACTOME TRANSCRIPTIONAL REGULATION BY VENTX	41	1.45e-03	2.87e-01	1.81e-02
REACTOME PREDNISONE ADME	10	1.56e-03	-5.78e-01	1.93e-02
REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS	55	1.84e-03	-2.43e-01	2.25e-02
REACTOME S PHASE	159	1.85e-03	1.43e-01	2.25e-02
REACTOME ANTIMICROBIAL PEPTIDES	76	1.86e-03	-2.06e-01	2.25e-02
REACTOME INTERLEUKIN 7 SIGNALING	31	1.91e-03	3.22e-01	2.28e-02
REACTOME MITOTIC G2 G2 M PHASES	194	2.02e-03	1.29e-01	2.40e-02
REACTOME O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS	38	2.19e-03	-2.87e-01	2.59e-02
REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	39	2.39e-03	-2.81e-01	2.81e-02
REACTOME LAMININ INTERACTIONS	28	2.42e-03	-3.31e-01	2.82e-02
REACTOME TRANSPORT OF SMALL MOLECULES	697	2.50e-03	-6.72e-02	2.90e-02
REACTOME TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE	39	2.77e-03	2.77e-01	3.18e-02
REACTOME GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER	25	2.81e-03	3.45e-01	3.20e-02
REACTOME PROTEIN FOLDING	96	2.84e-03	1.76e-01	3.20e-02
REACTOME VESICLE MEDIATED TRANSPORT	642	2.84e-03	6.90e-02	3.20e-02
REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS	101	3.21e-03	-1.70e-01	3.56e-02
REACTOME SIGNALING BY NTRKS	132	3.21e-03	1.49e-01	3.56e-02
REACTOME INTERLEUKIN 6 FAMILY SIGNALING	24	3.25e-03	3.47e-01	3.56e-02
REACTOME GLUCURONIDATION	23	3.25e-03	-3.54e-01	3.56e-02
REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH	62	3.29e-03	-2.16e-01	3.57e-02
REACTOME TOLL LIKE RECEPTOR CASCADES	158	3.30e-03	1.35e-01	3.57e-02
REACTOME DUAL INCISION IN GG NER	39	3.35e-03	2.71e-01	3.60e-02
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES	10	3.48e-03	5.34e-01	3.71e-02
REACTOME INTERLEUKIN 6 SIGNALING	11	3.62e-03	5.07e-01	3.83e-02
REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE	11	3.78e-03	-5.04e-01	3.97e-02
REACTOME DNA DAMAGE BYPASS	47	3.79e-03	2.44e-01	3.97e-02
REACTOME TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER	76	3.89e-03	1.91e-01	4.05e-02
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES	49	3.99e-03	2.38e-01	4.09e-02
REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION	89	4.00e-03	1.76e-01	4.09e-02
REACTOME EICOSANOID LIGAND BINDING RECEPTORS	14	4.01e-03	4.44e-01	4.09e-02
REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	30	4.40e-03	-3.00e-01	4.46e-02
REACTOME RESOLUTION OF ABASIC SITES AP SITES	38	4.45e-03	2.67e-01	4.48e-02
REACTOME HORMONE LIGAND BINDING RECEPTORS	12	4.67e-03	-4.72e-01	4.68e-02
REACTOME SIGNALING BY CSF3 G CSF	30	4.79e-03	2.98e-01	4.74e-02
REACTOME ACTIVATION OF C3 AND C5	6	4.80e-03	-6.65e-01	4.74e-02
REACTOME TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN	21	4.88e-03	3.55e-01	4.80e-02
REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	111	5.04e-03	1.54e-01	4.90e-02
REACTOME SIGNALING BY SCF KIT	42	5.05e-03	2.50e-01	4.90e-02
REACTOME PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR	21	5.16e-03	3.53e-01	4.99e-02
REACTOME INTERFERON SIGNALING	193	5.53e-03	1.16e-01	5.29e-02
REACTOME INTERFERON ALPHA BETA SIGNALING	70	5.55e-03	1.92e-01	5.29e-02
REACTOME MITOTIC METAPHASE AND ANAPHASE	228	5.66e-03	1.06e-01	5.37e-02
REACTOME SYNTHESIS OF DNA	119	5.72e-03	1.47e-01	5.40e-02
REACTOME SIGNALING BY RETINOIC ACID	41	5.91e-03	2.48e-01	5.54e-02
REACTOME NCAM1 INTERACTIONS	41	6.01e-03	-2.48e-01	5.61e-02
REACTOME FLT3 SIGNALING	38	6.11e-03	2.57e-01	5.67e-02
REACTOME PHASE 0 RAPID DEPOLARISATION	31	6.20e-03	-2.84e-01	5.69e-02
REACTOME INFLUENZA INFECTION	149	6.20e-03	1.30e-01	5.69e-02
REACTOME PHOSPHORYLATION OF THE APC C	20	6.32e-03	3.53e-01	5.76e-02
REACTOME TP53 REGULATES METABOLIC GENES	81	6.36e-03	1.75e-01	5.77e-02
REACTOME PROTEIN LOCALIZATION	153	6.53e-03	1.27e-01	5.89e-02
REACTOME VITAMIN C ASCORBATE METABOLISM	8	6.60e-03	5.55e-01	5.92e-02
REACTOME ACYL CHAIN REMODELLING OF PC	27	6.66e-03	-3.02e-01	5.92e-02
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES	11	6.67e-03	4.72e-01	5.92e-02
REACTOME DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE	76	6.74e-03	1.80e-01	5.95e-02
REACTOME MET PROMOTES CELL MOTILITY	41	6.94e-03	-2.44e-01	6.10e-02
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	105	7.03e-03	1.52e-01	6.14e-02
REACTOME ENDOSOMAL VACUOLAR PATHWAY	11	7.14e-03	4.68e-01	6.21e-02
REACTOME CONJUGATION OF BENZOATE WITH GLYCINE	6	7.36e-03	-6.32e-01	6.36e-02
REACTOME ONCOGENE INDUCED SENESCENCE	35	7.45e-03	2.61e-01	6.38e-02
REACTOME CYTOPROTECTION BY HMOX1	59	7.48e-03	2.01e-01	6.38e-02
REACTOME TERMINATION OF TRANSLESION DNA SYNTHESIS	32	7.51e-03	2.73e-01	6.38e-02
REACTOME IRE1ALPHA ACTIVATES CHAPERONES	48	7.54e-03	2.23e-01	6.38e-02
REACTOME NONHOMOLOGOUS END JOINING NHEJ	64	7.63e-03	1.93e-01	6.40e-02
REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION	145	7.67e-03	1.28e-01	6.40e-02
REACTOME DNA DOUBLE STRAND BREAK RESPONSE	74	7.67e-03	1.79e-01	6.40e-02
REACTOME MEIOSIS	110	7.79e-03	1.47e-01	6.45e-02
REACTOME FORMATION OF AXIAL MESODERM	14	7.82e-03	4.11e-01	6.45e-02
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS	161	8.09e-03	1.21e-01	6.64e-02
REACTOME UCH PROTEINASES	99	8.50e-03	1.53e-01	6.95e-02
REACTOME FORMATION OF LATERAL PLATE MESODERM	5	9.05e-03	6.74e-01	7.36e-02
REACTOME SARS COV 2 INFECTION	281	9.38e-03	9.01e-02	7.58e-02
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE GIP	12	9.42e-03	4.33e-01	7.58e-02
REACTOME RESPONSE TO METAL IONS	14	9.54e-03	4.00e-01	7.64e-02
REACTOME GASTRULATION	49	9.72e-03	2.13e-01	7.75e-02
REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE	109	1.01e-02	1.43e-01	8.05e-02
REACTOME HDR THROUGH SINGLE STRAND ANNEALING SSA	37	1.04e-02	2.43e-01	8.19e-02
REACTOME SIGNALING BY ACTIVIN	15	1.06e-02	3.81e-01	8.29e-02
REACTOME METALLOPROTEASE DUBS	36	1.13e-02	2.44e-01	8.87e-02
REACTOME NEGATIVE REGULATION OF FLT3	15	1.15e-02	3.77e-01	8.96e-02
REACTOME DIGESTION OF DIETARY LIPID	7	1.17e-02	-5.50e-01	9.10e-02
REACTOME O LINKED GLYCOSYLATION	109	1.19e-02	-1.39e-01	9.11e-02
REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE	71	1.19e-02	1.73e-01	9.11e-02
REACTOME HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE	43	1.20e-02	2.21e-01	9.15e-02
REACTOME MITOTIC PROMETAPHASE	194	1.22e-02	1.04e-01	9.26e-02
REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES	78	1.28e-02	1.63e-01	9.67e-02
REACTOME PROGRAMMED CELL DEATH	204	1.29e-02	1.01e-01	9.67e-02
REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS	8	1.29e-02	-5.07e-01	9.67e-02
REACTOME RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX	29	1.30e-02	2.67e-01	9.67e-02
REACTOME ACYL CHAIN REMODELLING OF PS	22	1.35e-02	-3.04e-01	9.98e-02
REACTOME ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS	20	1.35e-02	3.19e-01	9.98e-02
REACTOME TRAIL SIGNALING	8	1.36e-02	5.04e-01	9.98e-02
REACTOME AMINO ACID CONJUGATION	9	1.37e-02	-4.75e-01	1.00e-01
REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE	277	1.42e-02	8.56e-02	1.03e-01
REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	28	1.43e-02	2.67e-01	1.04e-01
REACTOME REGULATION OF PTEN GENE TRANSCRIPTION	59	1.44e-02	1.84e-01	1.04e-01
REACTOME DISEASES OF DNA REPAIR	51	1.46e-02	1.98e-01	1.05e-01
REACTOME EICOSANOIDS	12	1.46e-02	-4.07e-01	1.05e-01
REACTOME CIPROFLOXACIN ADME	5	1.47e-02	-6.30e-01	1.05e-01
REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	20	1.48e-02	3.15e-01	1.05e-01
REACTOME XENOBIOTICS	22	1.53e-02	-2.99e-01	1.08e-01
REACTOME INTERLEUKIN 27 SIGNALING	11	1.54e-02	4.22e-01	1.08e-01
REACTOME INACTIVATION OF CSF3 G CSF SIGNALING	25	1.55e-02	2.80e-01	1.08e-01
REACTOME INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION	21	1.56e-02	-3.05e-01	1.08e-01
REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	24	1.56e-02	2.85e-01	1.08e-01
REACTOME METALLOTHIONEINS BIND METALS	11	1.58e-02	4.20e-01	1.09e-01
REACTOME SARS COV 1 HOST INTERACTIONS	92	1.58e-02	1.46e-01	1.09e-01
REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	18	1.60e-02	-3.28e-01	1.10e-01
REACTOME BETA DEFENSINS	27	1.68e-02	-2.66e-01	1.15e-01
REACTOME INTERLEUKIN 12 FAMILY SIGNALING	53	1.69e-02	1.90e-01	1.15e-01
REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY	25	1.69e-02	2.76e-01	1.15e-01
REACTOME ANCHORING FIBRIL FORMATION	13	1.70e-02	-3.82e-01	1.15e-01
REACTOME TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS	82	1.72e-02	-1.52e-01	1.16e-01
REACTOME DAP12 SIGNALING	27	1.77e-02	2.64e-01	1.19e-01
REACTOME OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS	8	1.78e-02	-4.84e-01	1.19e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE	5	1.80e-02	6.11e-01	1.19e-01
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	55	1.81e-02	-1.84e-01	1.20e-01
REACTOME DISEASES OF METABOLISM	237	1.81e-02	-8.91e-02	1.20e-01
REACTOME ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS	27	1.82e-02	2.62e-01	1.20e-01
REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	15	1.83e-02	-3.52e-01	1.20e-01
REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS	28	1.88e-02	2.56e-01	1.23e-01
REACTOME INTERLEUKIN 2 SIGNALING	11	1.89e-02	4.09e-01	1.23e-01
REACTOME SIGNALING BY ROBO RECEPTORS	206	1.90e-02	9.48e-02	1.23e-01
REACTOME ACYL CHAIN REMODELLING OF PG	18	1.92e-02	-3.19e-01	1.24e-01
REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	91	1.94e-02	1.42e-01	1.24e-01
REACTOME RESPIRATORY ELECTRON TRANSPORT	90	1.94e-02	1.43e-01	1.24e-01
REACTOME TRNA PROCESSING	105	1.97e-02	1.32e-01	1.25e-01
REACTOME MEIOTIC SYNAPSIS	73	1.98e-02	1.58e-01	1.26e-01
REACTOME AMYLOID FIBER FORMATION	102	2.00e-02	1.33e-01	1.26e-01
REACTOME MHC CLASS II ANTIGEN PRESENTATION	121	2.05e-02	1.22e-01	1.28e-01
REACTOME INTERFERON GAMMA SIGNALING	88	2.05e-02	1.43e-01	1.28e-01
REACTOME FOXO MEDIATED TRANSCRIPTION	65	2.05e-02	1.66e-01	1.28e-01
REACTOME DUAL INCISION IN TC NER	63	2.06e-02	1.69e-01	1.28e-01
REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES	34	2.07e-02	2.29e-01	1.28e-01
REACTOME PERK REGULATES GENE EXPRESSION	31	2.11e-02	2.39e-01	1.30e-01
REACTOME KERATAN SULFATE DEGRADATION	13	2.16e-02	-3.68e-01	1.33e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES	8	2.20e-02	4.68e-01	1.35e-01
REACTOME SULFIDE OXIDATION TO SULFATE	6	2.23e-02	5.39e-01	1.36e-01
REACTOME TBC RABGAPS	40	2.25e-02	2.08e-01	1.37e-01
REACTOME MATURATION OF SARS COV 1 SPIKE PROTEIN	5	2.26e-02	5.89e-01	1.37e-01
REACTOME REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION	84	2.28e-02	1.44e-01	1.38e-01
REACTOME DEFECTIVE CHST6 CAUSES MCDC1	8	2.29e-02	-4.65e-01	1.38e-01
REACTOME METABOLISM OF FAT SOLUBLE VITAMINS	46	2.32e-02	-1.93e-01	1.39e-01
REACTOME EUKARYOTIC TRANSLATION ELONGATION	87	2.34e-02	1.41e-01	1.39e-01
REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS	81	2.35e-02	1.46e-01	1.39e-01
REACTOME APOPTOSIS	173	2.35e-02	9.98e-02	1.39e-01
REACTOME HIV INFECTION	223	2.35e-02	8.80e-02	1.39e-01
REACTOME KEAP1 NFE2L2 PATHWAY	104	2.41e-02	1.28e-01	1.42e-01
REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF	53	2.45e-02	1.79e-01	1.44e-01
REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX	15	2.49e-02	3.35e-01	1.45e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES	61	2.50e-02	1.66e-01	1.45e-01
REACTOME ASPARAGINE N LINKED GLYCOSYLATION	299	2.50e-02	7.54e-02	1.45e-01
REACTOME TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION	5	2.51e-02	5.78e-01	1.45e-01
REACTOME ARACHIDONIC ACID METABOLISM	57	2.52e-02	-1.71e-01	1.45e-01
REACTOME CARDIAC CONDUCTION	125	2.55e-02	-1.16e-01	1.46e-01
REACTOME FC EPSILON RECEPTOR FCERI SIGNALING	127	2.56e-02	1.15e-01	1.46e-01
REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS	42	2.58e-02	-1.99e-01	1.47e-01
REACTOME MITOCHONDRIAL BIOGENESIS	87	2.59e-02	1.38e-01	1.47e-01
REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS	6	2.60e-02	-5.25e-01	1.47e-01
REACTOME AURKA ACTIVATION BY TPX2	69	2.61e-02	1.55e-01	1.47e-01
REACTOME RETINOID CYCLE DISEASE EVENTS	11	2.64e-02	-3.87e-01	1.48e-01
REACTOME SEPARATION OF SISTER CHROMATIDS	184	2.64e-02	9.49e-02	1.48e-01
REACTOME EUKARYOTIC TRANSLATION INITIATION	110	2.69e-02	1.22e-01	1.50e-01
REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS	18	2.73e-02	3.00e-01	1.52e-01
REACTOME SARS COV 2 HOST INTERACTIONS	191	2.73e-02	9.26e-02	1.52e-01
REACTOME SIGNALING BY THE B CELL RECEPTOR BCR	106	2.78e-02	1.24e-01	1.54e-01
REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	86	2.79e-02	1.37e-01	1.54e-01
REACTOME ETHANOL OXIDATION	12	2.86e-02	-3.65e-01	1.57e-01
REACTOME THE PHOTOTRANSDUCTION CASCADE	32	2.91e-02	-2.23e-01	1.58e-01
REACTOME STRIATED MUSCLE CONTRACTION	35	2.92e-02	-2.13e-01	1.58e-01
REACTOME HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR IN THE PRESENCE OF LIGAND	55	2.92e-02	1.70e-01	1.58e-01
REACTOME MYD88 INDEPENDENT TLR4 CASCADE	103	2.93e-02	1.24e-01	1.58e-01
REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS	43	2.94e-02	1.92e-01	1.58e-01
REACTOME RHOBTB GTPASE CYCLE	34	2.94e-02	2.16e-01	1.58e-01
REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC	198	2.98e-02	8.96e-02	1.60e-01
REACTOME DIGESTION OF DIETARY CARBOHYDRATE	6	3.07e-02	-5.10e-01	1.64e-01
REACTOME G ALPHA I SIGNALLING EVENTS	304	3.08e-02	-7.20e-02	1.64e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES	33	3.12e-02	2.17e-01	1.66e-01
REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	36	3.13e-02	2.07e-01	1.66e-01
REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY	72	3.15e-02	1.47e-01	1.66e-01
REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	129	3.16e-02	1.10e-01	1.66e-01
REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY	46	3.22e-02	1.83e-01	1.69e-01
REACTOME MITOTIC SPINDLE CHECKPOINT	109	3.26e-02	1.18e-01	1.70e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX2	117	3.26e-02	1.14e-01	1.70e-01
REACTOME SIGNALING BY TGFB FAMILY MEMBERS	119	3.26e-02	1.13e-01	1.70e-01
REACTOME BIOSYNTHESIS OF MARESINS	8	3.30e-02	-4.35e-01	1.71e-01
REACTOME DEGRADATION OF CYSTEINE AND HOMOCYSTEINE	15	3.32e-02	3.18e-01	1.71e-01
REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	20	3.36e-02	2.74e-01	1.73e-01
REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION	8	3.36e-02	-4.34e-01	1.73e-01
REACTOME RHO GTPASE CYCLE	423	3.49e-02	5.98e-02	1.77e-01
REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	38	3.49e-02	1.98e-01	1.77e-01
REACTOME FORMATION OF INCISION COMPLEX IN GG NER	40	3.49e-02	1.93e-01	1.77e-01
REACTOME TRIF MEDIATED PROGRAMMED CELL DEATH	9	3.50e-02	4.06e-01	1.77e-01
REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	57	3.52e-02	1.61e-01	1.77e-01
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY	33	3.52e-02	2.12e-01	1.77e-01
REACTOME DEADENYLATION DEPENDENT MRNA DECAY	56	3.52e-02	1.63e-01	1.77e-01
REACTOME TOLL LIKE RECEPTOR 9 TLR9 CASCADE	100	3.55e-02	1.22e-01	1.78e-01
REACTOME TRANSLESION SYNTHESIS BY POLH	19	3.63e-02	2.77e-01	1.80e-01
REACTOME PTEN REGULATION	135	3.63e-02	1.04e-01	1.80e-01
REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	9	3.64e-02	-4.03e-01	1.80e-01
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY	94	3.66e-02	1.25e-01	1.81e-01
REACTOME PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING	11	3.67e-02	-3.64e-01	1.81e-01
REACTOME NUCLEAR EVENTS MEDIATED BY NFE2L2	77	3.70e-02	1.38e-01	1.81e-01
REACTOME DISEASES OF MITOTIC CELL CYCLE	37	3.70e-02	1.98e-01	1.81e-01
REACTOME SENSORY PERCEPTION OF SALTY TASTE	6	3.73e-02	-4.91e-01	1.82e-01
REACTOME LYSOSOME VESICLE BIOGENESIS	33	3.74e-02	2.09e-01	1.82e-01
REACTOME POTENTIAL THERAPEUTICS FOR SARS	92	3.76e-02	1.25e-01	1.83e-01
REACTOME INSULIN PROCESSING	24	3.80e-02	2.45e-01	1.84e-01
REACTOME RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK	47	3.80e-02	1.75e-01	1.84e-01
REACTOME TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA	17	3.82e-02	2.90e-01	1.84e-01
REACTOME PEROXISOMAL PROTEIN IMPORT	62	3.83e-02	1.52e-01	1.84e-01
REACTOME STIMULI SENSING CHANNELS	100	3.84e-02	-1.20e-01	1.84e-01
REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	118	3.92e-02	-1.10e-01	1.87e-01
REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS	418	3.92e-02	5.88e-02	1.87e-01
REACTOME TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX	14	3.95e-02	3.18e-01	1.87e-01
REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE	5	3.96e-02	-5.31e-01	1.87e-01
REACTOME ABACAVIR ADME	9	4.03e-02	-3.95e-01	1.90e-01
REACTOME RNA POLYMERASE II PRE TRANSCRIPTION EVENTS	77	4.04e-02	1.35e-01	1.90e-01
REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	9	4.08e-02	3.94e-01	1.92e-01
REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION	31	4.17e-02	2.11e-01	1.94e-01
REACTOME RHO GTPASES ACTIVATE FORMINS	136	4.18e-02	1.01e-01	1.94e-01
REACTOME ACYL CHAIN REMODELLING OF PI	17	4.18e-02	-2.85e-01	1.94e-01
REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION	23	4.18e-02	-2.45e-01	1.94e-01
REACTOME COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING	32	4.28e-02	2.07e-01	1.98e-01
REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA	28	4.35e-02	2.20e-01	2.01e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM	38	4.38e-02	-1.89e-01	2.01e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST	18	4.42e-02	2.74e-01	2.03e-01
REACTOME CREATINE METABOLISM	9	4.47e-02	3.86e-01	2.04e-01
REACTOME SELECTIVE AUTOPHAGY	79	4.49e-02	1.31e-01	2.05e-01
REACTOME HEMOSTASIS	591	4.62e-02	4.80e-02	2.10e-01
REACTOME ION CHANNEL TRANSPORT	172	4.64e-02	-8.80e-02	2.11e-01
REACTOME EXTENSION OF TELOMERES	49	4.67e-02	1.64e-01	2.11e-01
REACTOME VASOPRESSIN LIKE RECEPTORS	5	4.69e-02	5.13e-01	2.12e-01
REACTOME CELLULAR RESPONSE TO STARVATION	147	4.71e-02	9.48e-02	2.12e-01
REACTOME CLEC7A INFLAMMASOME PATHWAY	6	4.80e-02	4.66e-01	2.15e-01
REACTOME CLEC7A DECTIN 1 SIGNALING	97	4.86e-02	1.16e-01	2.17e-01
REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE	19	4.90e-02	2.61e-01	2.18e-01
REACTOME DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15	8	4.99e-02	-4.00e-01	2.22e-01
REACTOME BH3 ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI APOPTOTIC BCL 2 MEMBERS	9	5.15e-02	3.75e-01	2.28e-01
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	81	5.21e-02	1.25e-01	2.30e-01
REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	26	5.22e-02	2.20e-01	2.30e-01
REACTOME VLDLR INTERNALISATION AND DEGRADATION	16	5.25e-02	2.80e-01	2.31e-01
REACTOME NUCLEAR ENVELOPE NE REASSEMBLY	74	5.26e-02	1.30e-01	2.31e-01
REACTOME DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A	5	5.27e-02	-5.00e-01	2.31e-01
REACTOME RNA POLYMERASE II TRANSCRIBES SNRNA GENES	77	5.29e-02	1.28e-01	2.31e-01
REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET	8	5.32e-02	-3.95e-01	2.31e-01
REACTOME ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS	11	5.32e-02	3.37e-01	2.31e-01
REACTOME DEFECTIVE GALNT3 CAUSES HFTC	16	5.38e-02	-2.78e-01	2.33e-01
REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	73	5.42e-02	1.30e-01	2.34e-01
REACTOME HYDROLYSIS OF LPC	9	5.48e-02	-3.70e-01	2.36e-01
REACTOME MAPK3 ERK1 ACTIVATION	10	5.57e-02	3.49e-01	2.39e-01
REACTOME HIV LIFE CYCLE	145	5.58e-02	9.20e-02	2.39e-01
REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS	29	5.59e-02	2.05e-01	2.39e-01
REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	16	5.64e-02	2.75e-01	2.40e-01
REACTOME TCR SIGNALING	113	5.65e-02	1.04e-01	2.40e-01
REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	53	5.66e-02	1.51e-01	2.40e-01
REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	9	5.66e-02	3.67e-01	2.40e-01
REACTOME CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND	16	5.68e-02	2.75e-01	2.40e-01
REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX	39	5.77e-02	1.76e-01	2.43e-01
REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	98	5.79e-02	1.11e-01	2.43e-01
REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	54	5.82e-02	1.49e-01	2.44e-01
REACTOME ALPHA OXIDATION OF PHYTANATE	6	5.86e-02	4.46e-01	2.45e-01
REACTOME RHOBTB1 GTPASE CYCLE	22	5.89e-02	2.33e-01	2.45e-01
REACTOME CROSSLINKING OF COLLAGEN FIBRILS	16	5.89e-02	-2.73e-01	2.45e-01
REACTOME APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS	87	5.92e-02	1.17e-01	2.45e-01
REACTOME TRNA PROCESSING IN THE NUCLEUS	58	5.96e-02	1.43e-01	2.47e-01
REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION	19	6.04e-02	-2.49e-01	2.49e-01
REACTOME SIGNALING BY ALK	26	6.11e-02	2.12e-01	2.51e-01
REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS	5	6.12e-02	-4.83e-01	2.51e-01
REACTOME REPRODUCTION	136	6.14e-02	9.29e-02	2.51e-01
REACTOME TRANSCRIPTION OF THE HIV GENOME	66	6.24e-02	1.33e-01	2.55e-01
REACTOME TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS	36	6.34e-02	1.79e-01	2.58e-01
REACTOME HIV ELONGATION ARREST AND RECOVERY	33	6.37e-02	1.86e-01	2.59e-01
REACTOME OPSINS	7	6.43e-02	-4.04e-01	2.60e-01
REACTOME REGULATED PROTEOLYSIS OF P75NTR	11	6.49e-02	3.21e-01	2.63e-01
REACTOME HS GAG BIOSYNTHESIS	28	6.52e-02	-2.01e-01	2.63e-01
REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS	8	6.55e-02	3.76e-01	2.63e-01
REACTOME PURINE CATABOLISM	17	6.64e-02	2.57e-01	2.65e-01
REACTOME CD163 MEDIATING AN ANTI INFLAMMATORY RESPONSE	9	6.65e-02	3.53e-01	2.65e-01
REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS	16	6.66e-02	-2.65e-01	2.65e-01
REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS	83	6.68e-02	1.16e-01	2.65e-01
REACTOME THE NLRP3 INFLAMMASOME	16	6.68e-02	2.65e-01	2.65e-01
REACTOME COPII MEDIATED VESICLE TRANSPORT	66	6.70e-02	1.30e-01	2.65e-01
REACTOME RHO GTPASES ACTIVATE WASPS AND WAVES	34	6.71e-02	1.81e-01	2.65e-01
REACTOME TELOMERE C STRAND LAGGING STRAND SYNTHESIS	33	6.71e-02	1.84e-01	2.65e-01
REACTOME TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE	10	6.72e-02	-3.34e-01	2.65e-01
REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	353	6.89e-02	5.64e-02	2.70e-01
REACTOME SIGNALING BY RECEPTOR TYROSINE KINASES	507	6.90e-02	4.72e-02	2.70e-01
REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	183	6.92e-02	7.79e-02	2.70e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES	16	6.93e-02	2.62e-01	2.70e-01
REACTOME SCAVENGING BY CLASS B RECEPTORS	6	6.97e-02	-4.28e-01	2.71e-01
REACTOME SPHINGOLIPID METABOLISM	84	6.97e-02	1.14e-01	2.71e-01
REACTOME INTERLEUKIN 36 PATHWAY	7	7.06e-02	-3.95e-01	2.73e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION	29	7.08e-02	1.94e-01	2.73e-01
REACTOME SENSORY PROCESSING OF SOUND	72	7.11e-02	-1.23e-01	2.74e-01
REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	38	7.23e-02	-1.68e-01	2.77e-01
REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	11	7.24e-02	3.13e-01	2.77e-01
REACTOME LEISHMANIA INFECTION	156	7.25e-02	8.33e-02	2.77e-01
REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS	299	7.29e-02	6.03e-02	2.79e-01
REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	52	7.47e-02	1.43e-01	2.84e-01
REACTOME MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS	13	7.48e-02	2.85e-01	2.84e-01
REACTOME FORMATION OF XYLULOSE 5 PHOSPHATE	5	7.52e-02	4.59e-01	2.85e-01
REACTOME N GLYCAN ANTENNAE ELONGATION	15	7.53e-02	2.65e-01	2.85e-01
REACTOME TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS	52	7.59e-02	1.42e-01	2.86e-01
REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	22	7.59e-02	2.19e-01	2.86e-01
REACTOME RAB GERANYLGERANYLATION	57	7.61e-02	1.36e-01	2.86e-01
REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION	10	7.64e-02	3.24e-01	2.86e-01
REACTOME SIGNALING BY GPCR	673	7.70e-02	-4.00e-02	2.88e-01
REACTOME PURINE SALVAGE	12	7.75e-02	2.94e-01	2.89e-01
REACTOME DEFENSINS	33	7.76e-02	-1.77e-01	2.89e-01
REACTOME SUMOYLATION OF TRANSCRIPTION FACTORS	20	7.80e-02	2.28e-01	2.90e-01
REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	21	7.86e-02	2.22e-01	2.91e-01
REACTOME DEFECTIVE EXT2 CAUSES EXOSTOSES 2	12	7.93e-02	-2.93e-01	2.93e-01
REACTOME AUTOPHAGY	144	7.98e-02	8.46e-02	2.94e-01
REACTOME CIRCADIAN CLOCK	68	8.03e-02	1.23e-01	2.95e-01
REACTOME STAT3 NUCLEAR EVENTS DOWNSTREAM OF ALK SIGNALING	9	8.04e-02	3.37e-01	2.95e-01
REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	16	8.07e-02	2.52e-01	2.96e-01
REACTOME CD22 MEDIATED BCR REGULATION	5	8.13e-02	4.50e-01	2.97e-01
REACTOME HISTIDINE CATABOLISM	8	8.36e-02	-3.53e-01	3.05e-01
REACTOME CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY	84	8.37e-02	1.09e-01	3.05e-01
REACTOME CRISTAE FORMATION	27	8.38e-02	1.92e-01	3.05e-01
REACTOME BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA	17	8.44e-02	2.42e-01	3.05e-01
REACTOME MAPK6 MAPK4 SIGNALING	91	8.49e-02	1.05e-01	3.05e-01
REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	13	8.51e-02	2.76e-01	3.05e-01
REACTOME DNA DAMAGE RECOGNITION IN GG NER	36	8.53e-02	1.66e-01	3.05e-01
REACTOME SIGNALING BY KIT IN DISEASE	20	8.55e-02	2.22e-01	3.05e-01
REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES	7	8.55e-02	3.75e-01	3.05e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	27	8.55e-02	-1.91e-01	3.05e-01
REACTOME SIGNALING BY FGFR1 IN DISEASE	38	8.58e-02	1.61e-01	3.05e-01
REACTOME HEME BIOSYNTHESIS	13	8.58e-02	2.75e-01	3.05e-01
REACTOME VITAMINS	6	8.61e-02	4.05e-01	3.05e-01
REACTOME PHASE 4 RESTING MEMBRANE POTENTIAL	19	8.61e-02	-2.27e-01	3.05e-01
REACTOME COSTIMULATION BY THE CD28 FAMILY	64	8.63e-02	1.24e-01	3.05e-01
REACTOME TRNA AMINOACYLATION	40	8.66e-02	1.57e-01	3.06e-01
REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	16	8.70e-02	2.47e-01	3.06e-01
REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	26	8.77e-02	1.93e-01	3.08e-01
REACTOME SYNTHESIS OF 5 EICOSATETRAENOIC ACIDS	9	8.84e-02	3.28e-01	3.10e-01
REACTOME CELLULAR RESPONSE TO HYPOXIA	74	8.97e-02	1.14e-01	3.14e-01
REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN	37	8.98e-02	1.61e-01	3.14e-01
REACTOME SIGNALING BY INTERLEUKINS	444	9.03e-02	4.69e-02	3.15e-01
REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	49	9.08e-02	1.40e-01	3.16e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA	27	9.11e-02	1.88e-01	3.16e-01
REACTOME CONDENSATION OF PROMETAPHASE CHROMOSOMES	11	9.11e-02	2.94e-01	3.16e-01
REACTOME SELENOAMINO ACID METABOLISM	108	9.14e-02	9.40e-02	3.16e-01
REACTOME RESOLUTION OF SISTER CHROMATID COHESION	120	9.16e-02	8.92e-02	3.16e-01
REACTOME CREB3 FACTORS ACTIVATE GENES	8	9.22e-02	3.44e-01	3.17e-01
REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES	18	9.25e-02	-2.29e-01	3.17e-01
REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES	34	9.25e-02	1.67e-01	3.17e-01
REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX	21	9.29e-02	-2.12e-01	3.17e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES	15	9.30e-02	2.51e-01	3.17e-01
REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	67	9.31e-02	1.19e-01	3.17e-01
REACTOME CYCLIN D ASSOCIATED EVENTS IN G1	46	9.40e-02	1.43e-01	3.19e-01
REACTOME RAC3 GTPASE CYCLE	85	9.42e-02	1.05e-01	3.19e-01
REACTOME REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE	81	9.59e-02	1.07e-01	3.25e-01
REACTOME HIV TRANSCRIPTION ELONGATION	42	9.67e-02	1.48e-01	3.27e-01
REACTOME PEPTIDE LIGAND BINDING RECEPTORS	188	9.70e-02	-7.02e-02	3.27e-01
REACTOME ABACAVIR TRANSMEMBRANE TRANSPORT	5	9.81e-02	-4.27e-01	3.30e-01
REACTOME HDR THROUGH MMEJ ALT NHEJ	12	9.82e-02	2.76e-01	3.30e-01
REACTOME FANCONI ANEMIA PATHWAY	35	9.92e-02	1.61e-01	3.32e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN	13	9.96e-02	2.64e-01	3.33e-01
REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	23	1.00e-01	1.98e-01	3.35e-01
REACTOME DEFECTIVE B4GALT1 CAUSES B4GALT1 CDG CDG 2D	8	1.02e-01	-3.34e-01	3.38e-01
REACTOME GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION	14	1.02e-01	2.53e-01	3.38e-01
REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES	27	1.02e-01	1.82e-01	3.38e-01
REACTOME GLYCOSPHINGOLIPID METABOLISM	39	1.02e-01	1.51e-01	3.38e-01
REACTOME DISEASES OF IMMUNE SYSTEM	29	1.03e-01	1.75e-01	3.41e-01
REACTOME COMMON PATHWAY OF FIBRIN CLOT FORMATION	21	1.04e-01	-2.05e-01	3.41e-01
REACTOME INTERLEUKIN 35 SIGNALLING	12	1.04e-01	2.71e-01	3.41e-01
REACTOME LYSOSPHINGOLIPID AND LPA RECEPTORS	14	1.04e-01	2.51e-01	3.41e-01
REACTOME RHOBTB2 GTPASE CYCLE	22	1.04e-01	2.00e-01	3.41e-01
REACTOME CITRIC ACID CYCLE TCA CYCLE	21	1.04e-01	2.05e-01	3.41e-01
REACTOME IRON UPTAKE AND TRANSPORT	56	1.04e-01	1.25e-01	3.41e-01
REACTOME SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE	91	1.05e-01	9.85e-02	3.41e-01
REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	37	1.05e-01	-1.54e-01	3.41e-01
REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	15	1.06e-01	2.41e-01	3.43e-01
REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS	16	1.06e-01	-2.33e-01	3.43e-01
REACTOME TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS	29	1.06e-01	1.73e-01	3.43e-01
REACTOME N GLYCAN TRIMMING AND ELONGATION IN THE CIS GOLGI	5	1.06e-01	4.17e-01	3.43e-01
REACTOME PI5P REGULATES TP53 ACETYLATION	9	1.07e-01	3.10e-01	3.44e-01
REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	80	1.07e-01	1.04e-01	3.44e-01
REACTOME ACTIVATION OF BH3 ONLY PROTEINS	30	1.07e-01	1.70e-01	3.44e-01
REACTOME KSRP KHSRP BINDS AND DESTABILIZES MRNA	17	1.07e-01	2.26e-01	3.44e-01
REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS	68	1.09e-01	1.13e-01	3.45e-01
REACTOME TIE2 SIGNALING	18	1.09e-01	2.18e-01	3.45e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX	91	1.09e-01	9.71e-02	3.45e-01
REACTOME SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS	16	1.09e-01	2.31e-01	3.45e-01
REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE	93	1.09e-01	9.60e-02	3.45e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL	15	1.10e-01	-2.38e-01	3.45e-01
REACTOME MITOPHAGY	28	1.10e-01	1.74e-01	3.45e-01
REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	23	1.10e-01	-1.92e-01	3.45e-01
REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP	41	1.11e-01	1.44e-01	3.45e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1	16	1.11e-01	2.30e-01	3.45e-01
REACTOME KERATAN SULFATE KERATIN METABOLISM	34	1.11e-01	-1.58e-01	3.45e-01
REACTOME DNA STRAND ELONGATION	31	1.11e-01	1.66e-01	3.45e-01
REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	63	1.11e-01	-1.16e-01	3.45e-01
REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	29	1.11e-01	1.71e-01	3.45e-01
REACTOME HOST INTERACTIONS OF HIV FACTORS	127	1.11e-01	8.19e-02	3.45e-01
REACTOME TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS	55	1.11e-01	1.24e-01	3.45e-01
REACTOME ER TO GOLGI ANTEROGRADE TRANSPORT	152	1.11e-01	7.48e-02	3.45e-01
REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION	62	1.12e-01	1.17e-01	3.48e-01
REACTOME REGULATION OF IFNG SIGNALING	14	1.13e-01	2.45e-01	3.48e-01
REACTOME TRANSLESION SYNTHESIS BY POLK	17	1.13e-01	2.22e-01	3.48e-01
REACTOME SPERM MOTILITY AND TAXES	9	1.13e-01	-3.05e-01	3.48e-01
REACTOME CYTOSOLIC TRNA AMINOACYLATION	22	1.15e-01	1.94e-01	3.53e-01
REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III	31	1.15e-01	1.63e-01	3.53e-01
REACTOME REGULATED NECROSIS	57	1.16e-01	1.20e-01	3.54e-01
REACTOME SULFUR AMINO ACID METABOLISM	27	1.17e-01	1.74e-01	3.57e-01
REACTOME SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA	52	1.18e-01	-1.25e-01	3.59e-01
REACTOME APEX1 INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	7	1.18e-01	3.41e-01	3.60e-01
REACTOME RHO GTPASES ACTIVATE ROCKS	19	1.19e-01	2.07e-01	3.60e-01
REACTOME REGULATION OF KIT SIGNALING	16	1.19e-01	2.25e-01	3.60e-01
REACTOME HS GAG DEGRADATION	19	1.20e-01	-2.06e-01	3.60e-01
REACTOME NUCLEOTIDE SALVAGE	21	1.20e-01	1.96e-01	3.60e-01
REACTOME FCERI MEDIATED MAPK ACTIVATION	32	1.20e-01	1.59e-01	3.60e-01
REACTOME BUDDING AND MATURATION OF HIV VIRION	28	1.21e-01	1.69e-01	3.63e-01
REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	17	1.21e-01	2.17e-01	3.63e-01
REACTOME PHASE II CONJUGATION OF COMPOUNDS	102	1.22e-01	-8.87e-02	3.63e-01
REACTOME CHYLOMICRON REMODELING	10	1.22e-01	-2.83e-01	3.63e-01
REACTOME GPCR LIGAND BINDING	444	1.22e-01	-4.28e-02	3.63e-01
REACTOME ATORVASTATIN ADME	9	1.23e-01	-2.97e-01	3.68e-01
REACTOME FLT3 SIGNALING IN DISEASE	28	1.25e-01	1.67e-01	3.73e-01
REACTOME PARASITE INFECTION	57	1.28e-01	1.17e-01	3.80e-01
REACTOME METABOLISM OF LIPIDS	709	1.29e-01	3.34e-02	3.84e-01
REACTOME INTERLEUKIN 15 SIGNALING	13	1.30e-01	2.42e-01	3.85e-01
REACTOME VEGFR2 MEDIATED CELL PROLIFERATION	19	1.30e-01	2.00e-01	3.85e-01
REACTOME MISMATCH REPAIR	15	1.31e-01	2.25e-01	3.85e-01
REACTOME CD28 CO STIMULATION	32	1.32e-01	1.54e-01	3.87e-01
REACTOME SIGNALING BY NODAL	20	1.33e-01	1.94e-01	3.91e-01
REACTOME SODIUM COUPLED PHOSPHATE COTRANSPORTERS	5	1.33e-01	-3.88e-01	3.91e-01
REACTOME PLASMA LIPOPROTEIN CLEARANCE	37	1.34e-01	1.42e-01	3.91e-01
REACTOME SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS	12	1.34e-01	2.50e-01	3.91e-01
REACTOME INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE	20	1.34e-01	1.94e-01	3.91e-01
REACTOME MELANIN BIOSYNTHESIS	5	1.35e-01	-3.86e-01	3.92e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	24	1.35e-01	-1.76e-01	3.93e-01
REACTOME SPRY REGULATION OF FGF SIGNALING	16	1.36e-01	2.16e-01	3.93e-01
REACTOME EPH EPHRIN SIGNALING	90	1.38e-01	9.04e-02	4.00e-01
REACTOME SMOOTH MUSCLE CONTRACTION	43	1.38e-01	-1.31e-01	4.00e-01
REACTOME PLATELET CALCIUM HOMEOSTASIS	27	1.39e-01	1.64e-01	4.02e-01
REACTOME CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY	25	1.40e-01	1.70e-01	4.03e-01
REACTOME SIGNALING BY FGFR2	72	1.40e-01	1.01e-01	4.03e-01
REACTOME ACTIVATION OF NIMA KINASES NEK9 NEK6 NEK7	7	1.40e-01	3.22e-01	4.03e-01
REACTOME INFLAMMASOMES	21	1.42e-01	1.85e-01	4.06e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES	43	1.42e-01	1.29e-01	4.06e-01
REACTOME LAGGING STRAND SYNTHESIS	19	1.43e-01	1.94e-01	4.09e-01
REACTOME CELLULAR HEXOSE TRANSPORT	21	1.44e-01	-1.84e-01	4.09e-01
REACTOME LOSS OF FUNCTION OF SMAD2 3 IN CANCER	7	1.44e-01	3.19e-01	4.09e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS	5	1.45e-01	3.77e-01	4.10e-01
REACTOME COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC	52	1.45e-01	1.17e-01	4.10e-01
REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING	34	1.45e-01	1.44e-01	4.10e-01
REACTOME CELLULAR RESPONSE TO HEAT STRESS	99	1.45e-01	8.48e-02	4.10e-01
REACTOME ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS	7	1.45e-01	3.18e-01	4.10e-01
REACTOME POLO LIKE KINASE MEDIATED EVENTS	16	1.46e-01	2.10e-01	4.10e-01
REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	37	1.46e-01	1.38e-01	4.11e-01
REACTOME GERM LAYER FORMATION AT GASTRULATION	17	1.47e-01	2.03e-01	4.13e-01
REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	35	1.48e-01	1.41e-01	4.13e-01
REACTOME RHO GTPASES ACTIVATE IQGAPS	31	1.48e-01	1.50e-01	4.13e-01
REACTOME RAF INDEPENDENT MAPK1 3 ACTIVATION	22	1.48e-01	1.78e-01	4.13e-01
REACTOME SYNTHESIS OF PC	27	1.48e-01	1.61e-01	4.13e-01
REACTOME HDL CLEARANCE	5	1.49e-01	3.73e-01	4.13e-01
REACTOME CILIUM ASSEMBLY	190	1.49e-01	6.07e-02	4.13e-01
REACTOME MISCELLANEOUS SUBSTRATES	12	1.49e-01	-2.41e-01	4.13e-01
REACTOME TRANSCRIPTIONAL REGULATION BY MECP2	60	1.49e-01	1.08e-01	4.14e-01
REACTOME CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2	11	1.50e-01	2.51e-01	4.14e-01
REACTOME METABOLISM OF NUCLEOTIDES	94	1.51e-01	8.57e-02	4.16e-01
REACTOME REGULATION OF SIGNALING BY NODAL	9	1.51e-01	2.76e-01	4.16e-01
REACTOME FGFR1B LIGAND BINDING AND ACTIVATION	6	1.52e-01	-3.38e-01	4.18e-01
REACTOME MATURATION OF SARS COV 2 SPIKE PROTEIN	35	1.54e-01	1.39e-01	4.22e-01
REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS	5	1.54e-01	-3.68e-01	4.22e-01
REACTOME PARACETAMOL ADME	26	1.55e-01	-1.61e-01	4.22e-01
REACTOME IRAK4 DEFICIENCY TLR2 4	17	1.55e-01	1.99e-01	4.22e-01
REACTOME HUR ELAVL1 BINDS AND STABILIZES MRNA	8	1.55e-01	2.90e-01	4.22e-01
REACTOME PHYSIOLOGICAL FACTORS	14	1.55e-01	2.20e-01	4.22e-01
REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	101	1.55e-01	-8.18e-02	4.22e-01
REACTOME RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS	5	1.56e-01	3.67e-01	4.22e-01
REACTOME GPVI MEDIATED ACTIVATION CASCADE	35	1.56e-01	1.38e-01	4.23e-01
REACTOME CGMP EFFECTS	16	1.57e-01	-2.04e-01	4.25e-01
REACTOME RELAXIN RECEPTORS	8	1.58e-01	-2.89e-01	4.26e-01
REACTOME PINK1 PRKN MEDIATED MITOPHAGY	22	1.60e-01	1.73e-01	4.30e-01
REACTOME SYNTHESIS OF DOLICHYL PHOSPHATE	6	1.60e-01	3.31e-01	4.30e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE	5	1.60e-01	3.62e-01	4.30e-01
REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	26	1.61e-01	1.59e-01	4.30e-01
REACTOME ADHERENS JUNCTIONS INTERACTIONS	33	1.61e-01	-1.41e-01	4.30e-01
REACTOME GABA RECEPTOR ACTIVATION	57	1.61e-01	-1.07e-01	4.30e-01
REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	16	1.61e-01	2.02e-01	4.30e-01
REACTOME P38MAPK EVENTS	13	1.62e-01	2.24e-01	4.32e-01
REACTOME INTERLEUKIN 23 SIGNALING	9	1.64e-01	2.68e-01	4.35e-01
REACTOME TRANSPORT OF ORGANIC ANIONS	10	1.64e-01	-2.54e-01	4.35e-01
REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM	50	1.64e-01	-1.14e-01	4.36e-01
REACTOME SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS	74	1.65e-01	9.33e-02	4.37e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	14	1.66e-01	-2.14e-01	4.38e-01
REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL	58	1.67e-01	1.05e-01	4.40e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION	45	1.67e-01	1.19e-01	4.40e-01
REACTOME SIGNALING BY FLT3 ITD AND TKD MUTANTS	16	1.69e-01	1.99e-01	4.44e-01
REACTOME NONSENSE MEDIATED DECAY NMD	107	1.70e-01	7.68e-02	4.46e-01
REACTOME INTERLEUKIN 18 SIGNALING	8	1.70e-01	-2.80e-01	4.47e-01
REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	8	1.71e-01	2.80e-01	4.47e-01
REACTOME RHOH GTPASE CYCLE	37	1.71e-01	1.30e-01	4.47e-01
REACTOME SUMOYLATION OF INTRACELLULAR RECEPTORS	29	1.71e-01	1.47e-01	4.48e-01
REACTOME SARS COV 2 TARGETS PDZ PROTEINS IN CELL CELL JUNCTION	5	1.72e-01	3.53e-01	4.49e-01
REACTOME FCERI MEDIATED NF KB ACTIVATION	78	1.73e-01	8.93e-02	4.49e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX3	94	1.73e-01	8.12e-02	4.51e-01
REACTOME FCERI MEDIATED CA 2 MOBILIZATION	30	1.74e-01	1.44e-01	4.51e-01
REACTOME G ALPHA Q SIGNALLING EVENTS	206	1.75e-01	-5.48e-02	4.52e-01
REACTOME P75NTR REGULATES AXONOGENESIS	9	1.75e-01	-2.61e-01	4.52e-01
REACTOME HDMS DEMETHYLATE HISTONES	40	1.75e-01	1.24e-01	4.52e-01
REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE	9	1.76e-01	-2.61e-01	4.52e-01
REACTOME PYRUVATE METABOLISM	29	1.76e-01	1.45e-01	4.52e-01
REACTOME TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE	20	1.76e-01	1.75e-01	4.52e-01
REACTOME GENERATION OF SECOND MESSENGER MOLECULES	30	1.76e-01	1.43e-01	4.52e-01
REACTOME NUCLEOTIDE CATABOLISM	35	1.76e-01	1.32e-01	4.52e-01
REACTOME SIGNALLING TO RAS	20	1.77e-01	1.75e-01	4.52e-01
REACTOME GAB1 SIGNALOSOME	17	1.78e-01	1.89e-01	4.55e-01
REACTOME CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT	19	1.79e-01	1.78e-01	4.55e-01
REACTOME DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE	30	1.79e-01	1.42e-01	4.55e-01
REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	19	1.79e-01	1.78e-01	4.55e-01
REACTOME RAC2 GTPASE CYCLE	81	1.79e-01	8.63e-02	4.55e-01
REACTOME CELL JUNCTION ORGANIZATION	89	1.80e-01	-8.22e-02	4.56e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING	5	1.80e-01	3.46e-01	4.56e-01
REACTOME THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT	77	1.81e-01	8.82e-02	4.56e-01
REACTOME CARGO CONCENTRATION IN THE ER	32	1.81e-01	1.37e-01	4.56e-01
REACTOME CHOLESTEROL BIOSYNTHESIS	25	1.81e-01	1.55e-01	4.56e-01
REACTOME SIGNALING BY PDGFR IN DISEASE	20	1.82e-01	1.72e-01	4.57e-01
REACTOME IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS	17	1.82e-01	1.87e-01	4.57e-01
REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX	13	1.83e-01	2.13e-01	4.58e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION TERMINATION	30	1.83e-01	1.40e-01	4.58e-01
REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	31	1.83e-01	1.38e-01	4.58e-01
REACTOME SYNDECAN INTERACTIONS	26	1.83e-01	-1.51e-01	4.58e-01
REACTOME CLATHRIN MEDIATED ENDOCYTOSIS	139	1.84e-01	6.53e-02	4.58e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	28	1.84e-01	1.45e-01	4.58e-01
REACTOME PCP CE PATHWAY	91	1.84e-01	8.05e-02	4.58e-01
REACTOME PEROXISOMAL LIPID METABOLISM	28	1.85e-01	1.45e-01	4.58e-01
REACTOME WNT MEDIATED ACTIVATION OF DVL	8	1.85e-01	2.71e-01	4.59e-01
REACTOME FORMATION OF TC NER PRE INCISION COMPLEX	51	1.86e-01	1.07e-01	4.60e-01
REACTOME CTLA4 INHIBITORY SIGNALING	21	1.88e-01	1.66e-01	4.63e-01
REACTOME INTESTINAL ABSORPTION	5	1.88e-01	-3.40e-01	4.64e-01
REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	12	1.88e-01	2.19e-01	4.64e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS	6	1.89e-01	3.10e-01	4.64e-01
REACTOME DECTIN 2 FAMILY	26	1.89e-01	-1.49e-01	4.64e-01
REACTOME HEDGEHOG LIGAND BIOGENESIS	64	1.90e-01	9.47e-02	4.64e-01
REACTOME INTERLEUKIN 21 SIGNALING	9	1.90e-01	2.52e-01	4.64e-01
REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	78	1.90e-01	8.58e-02	4.64e-01
REACTOME REACTIONS SPECIFIC TO THE COMPLEX N GLYCAN SYNTHESIS PATHWAY	10	1.90e-01	-2.39e-01	4.64e-01
REACTOME MAPK FAMILY SIGNALING CASCADES	314	1.91e-01	4.29e-02	4.65e-01
REACTOME TERMINAL PATHWAY OF COMPLEMENT	8	1.91e-01	-2.67e-01	4.66e-01
REACTOME FATTY ACIDS	15	1.93e-01	-1.94e-01	4.68e-01
REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	31	1.93e-01	1.35e-01	4.68e-01
REACTOME BETA CATENIN PHOSPHORYLATION CASCADE	16	1.93e-01	1.88e-01	4.68e-01
REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND	21	1.95e-01	1.63e-01	4.71e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX IN CANCER	8	1.95e-01	2.64e-01	4.71e-01
REACTOME INTERLEUKIN 1 SIGNALING	110	1.96e-01	7.14e-02	4.72e-01
REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	91	1.96e-01	-7.84e-02	4.73e-01
REACTOME ERBB2 REGULATES CELL MOTILITY	15	1.97e-01	-1.92e-01	4.74e-01
REACTOME TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA	36	1.99e-01	1.24e-01	4.77e-01
REACTOME ERBB2 ACTIVATES PTK6 SIGNALING	13	1.99e-01	-2.06e-01	4.77e-01
REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	51	2.00e-01	1.04e-01	4.78e-01
REACTOME EPHB MEDIATED FORWARD SIGNALING	41	2.00e-01	1.16e-01	4.78e-01
REACTOME SIGNALING BY FGFR4	40	2.00e-01	1.17e-01	4.78e-01
REACTOME RND1 GTPASE CYCLE	41	2.01e-01	1.15e-01	4.79e-01
REACTOME BICARBONATE TRANSPORTERS	10	2.02e-01	-2.33e-01	4.79e-01
REACTOME PHASE 2 PLATEAU PHASE	14	2.02e-01	-1.97e-01	4.79e-01
REACTOME DEFECTIVE LFNG CAUSES SCDO3	5	2.02e-01	-3.30e-01	4.79e-01
REACTOME PLASMA LIPOPROTEIN REMODELING	33	2.03e-01	-1.28e-01	4.81e-01
REACTOME MINERALOCORTICOID BIOSYNTHESIS	6	2.04e-01	-3.00e-01	4.81e-01
REACTOME ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION	16	2.04e-01	1.83e-01	4.81e-01
REACTOME TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS	43	2.04e-01	1.12e-01	4.81e-01
REACTOME REGULATION OF RUNX1 EXPRESSION AND ACTIVITY	17	2.05e-01	1.78e-01	4.81e-01
REACTOME MODULATION BY MTB OF HOST IMMUNE SYSTEM	6	2.05e-01	2.99e-01	4.81e-01
REACTOME REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR	11	2.06e-01	2.20e-01	4.84e-01
REACTOME FREE FATTY ACID RECEPTORS	5	2.07e-01	3.26e-01	4.85e-01
REACTOME METABOLISM OF POLYAMINES	56	2.08e-01	9.72e-02	4.88e-01
REACTOME ATTENUATION PHASE	27	2.09e-01	1.40e-01	4.88e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX	19	2.09e-01	1.66e-01	4.89e-01
REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES	39	2.10e-01	1.16e-01	4.91e-01
REACTOME GLYCOSAMINOGLYCAN METABOLISM	118	2.11e-01	-6.67e-02	4.91e-01
REACTOME ION TRANSPORT BY P TYPE ATPASES	51	2.11e-01	-1.01e-01	4.92e-01
REACTOME FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS	8	2.13e-01	-2.54e-01	4.95e-01
REACTOME SIGNALING BY CSF1 M CSF IN MYELOID CELLS	30	2.14e-01	1.31e-01	4.95e-01
REACTOME NEUROTOXICITY OF CLOSTRIDIUM TOXINS	10	2.14e-01	2.27e-01	4.95e-01
REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION	23	2.14e-01	1.50e-01	4.95e-01
REACTOME DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX	83	2.16e-01	7.86e-02	4.97e-01
REACTOME RHOT1 GTPASE CYCLE	5	2.16e-01	3.20e-01	4.97e-01
REACTOME INTERLEUKIN 12 SIGNALING	43	2.16e-01	1.09e-01	4.97e-01
REACTOME SYNTHESIS OF PE	13	2.17e-01	1.98e-01	4.97e-01
REACTOME ORGANIC ANION TRANSPORTERS	10	2.17e-01	2.26e-01	4.97e-01
REACTOME HDL ASSEMBLY	8	2.17e-01	-2.52e-01	4.97e-01
REACTOME MUCOPOLYSACCHARIDOSES	10	2.18e-01	-2.25e-01	4.98e-01
REACTOME BILE ACID AND BILE SALT METABOLISM	45	2.19e-01	-1.06e-01	5.00e-01
REACTOME DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS	19	2.19e-01	1.63e-01	5.00e-01
REACTOME RIPK1 MEDIATED REGULATED NECROSIS	30	2.20e-01	1.29e-01	5.01e-01
REACTOME RAS SIGNALING DOWNSTREAM OF NF1 LOSS OF FUNCTION VARIANTS	7	2.21e-01	2.67e-01	5.04e-01
REACTOME SIGNALING BY MET	78	2.21e-01	-8.01e-02	5.04e-01
REACTOME SCAVENGING OF HEME FROM PLASMA	13	2.22e-01	-1.96e-01	5.05e-01
REACTOME MAPK1 ERK2 ACTIVATION	9	2.23e-01	2.35e-01	5.05e-01
REACTOME METABOLISM OF INGESTED SEMET SEC MESEC INTO H2SE	7	2.23e-01	-2.66e-01	5.05e-01
REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	79	2.23e-01	7.92e-02	5.05e-01
REACTOME PKMTS METHYLATE HISTONE LYSINES	64	2.24e-01	8.80e-02	5.05e-01
REACTOME DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE	17	2.24e-01	-1.70e-01	5.05e-01
REACTOME ACTIVATION OF CASPASES THROUGH APOPTOSOME MEDIATED CLEAVAGE	5	2.24e-01	3.14e-01	5.05e-01
REACTOME HEME DEGRADATION	15	2.25e-01	-1.81e-01	5.07e-01
REACTOME TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY	16	2.26e-01	1.75e-01	5.07e-01
REACTOME INTERLEUKIN 9 SIGNALING	7	2.26e-01	2.64e-01	5.07e-01
REACTOME SYNTHESIS OF 15 EICOSATETRAENOIC ACID DERIVATIVES	6	2.26e-01	2.85e-01	5.07e-01
REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL	41	2.27e-01	1.09e-01	5.07e-01
REACTOME RIP MEDIATED NFKB ACTIVATION VIA ZBP1	16	2.27e-01	1.74e-01	5.07e-01
REACTOME PROCESSING OF INTRONLESS PRE MRNAS	19	2.27e-01	1.60e-01	5.07e-01
REACTOME KERATAN SULFATE BIOSYNTHESIS	28	2.28e-01	-1.32e-01	5.07e-01
REACTOME UPTAKE OF DIETARY COBALAMINS INTO ENTEROCYTES	9	2.30e-01	-2.31e-01	5.11e-01
REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM	23	2.30e-01	1.45e-01	5.11e-01
REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION	26	2.30e-01	1.36e-01	5.11e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION TERMINATION	23	2.32e-01	1.44e-01	5.12e-01
REACTOME SIGNALING BY FLT3 FUSION PROTEINS	19	2.32e-01	1.59e-01	5.12e-01
REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	20	2.32e-01	1.54e-01	5.12e-01
REACTOME FERTILIZATION	26	2.32e-01	-1.35e-01	5.12e-01
REACTOME NUCLEAR IMPORT OF REV PROTEIN	34	2.33e-01	1.18e-01	5.13e-01
REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	14	2.33e-01	1.84e-01	5.13e-01
REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	15	2.34e-01	-1.77e-01	5.15e-01
REACTOME SIGNALING BY NTRK3 TRKC	17	2.35e-01	1.66e-01	5.16e-01
REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	9	2.36e-01	-2.28e-01	5.16e-01
REACTOME LATE SARS COV 2 INFECTION EVENTS	67	2.36e-01	8.37e-02	5.17e-01
REACTOME L1CAM INTERACTIONS	112	2.36e-01	-6.48e-02	5.17e-01
REACTOME AGGREPHAGY	42	2.37e-01	1.05e-01	5.18e-01
REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	19	2.38e-01	1.57e-01	5.18e-01
REACTOME SIGNAL AMPLIFICATION	33	2.38e-01	1.19e-01	5.19e-01
REACTOME INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING	103	2.39e-01	6.72e-02	5.19e-01
REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS	6	2.40e-01	2.77e-01	5.19e-01
REACTOME INTERLEUKIN 17 SIGNALING	66	2.40e-01	8.37e-02	5.19e-01
REACTOME RET SIGNALING	40	2.40e-01	1.07e-01	5.19e-01
REACTOME HSF1 ACTIVATION	29	2.41e-01	1.26e-01	5.21e-01
REACTOME G0 AND EARLY G1	27	2.43e-01	1.30e-01	5.24e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION	41	2.44e-01	1.05e-01	5.26e-01
REACTOME ACYL CHAIN REMODELLING OF PE	29	2.46e-01	-1.24e-01	5.31e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	34	2.48e-01	-1.15e-01	5.33e-01
REACTOME ACTIVATION OF AMPK DOWNSTREAM OF NMDARS	28	2.48e-01	1.26e-01	5.33e-01
REACTOME SIGNALING BY HIPPO	19	2.48e-01	-1.53e-01	5.33e-01
REACTOME NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS	11	2.48e-01	2.01e-01	5.33e-01
REACTOME REGULATION OF FZD BY UBIQUITINATION	21	2.51e-01	-1.45e-01	5.37e-01
REACTOME METABOLISM OF AMINE DERIVED HORMONES	17	2.52e-01	-1.60e-01	5.39e-01
REACTOME LTC4 CYSLTR MEDIATED IL4 PRODUCTION	6	2.52e-01	-2.70e-01	5.39e-01
REACTOME C TYPE LECTIN RECEPTORS CLRS	136	2.53e-01	5.68e-02	5.39e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY	19	2.54e-01	-1.51e-01	5.41e-01
REACTOME SIGNALING BY EGFR	49	2.54e-01	9.41e-02	5.41e-01
REACTOME STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS	10	2.55e-01	2.08e-01	5.42e-01
REACTOME RECYCLING PATHWAY OF L1	43	2.55e-01	1.00e-01	5.42e-01
REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	17	2.56e-01	1.59e-01	5.42e-01
REACTOME SYNTHESIS OF DIPHTHAMIDE EEF2	8	2.56e-01	2.32e-01	5.42e-01
REACTOME DEFECTS IN COBALAMIN B12 METABOLISM	13	2.57e-01	1.82e-01	5.43e-01
REACTOME RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION	6	2.57e-01	2.67e-01	5.43e-01
REACTOME INSULIN RECEPTOR RECYCLING	29	2.58e-01	1.21e-01	5.43e-01
REACTOME BETA OXIDATION OF BUTANOYL COA TO ACETYL COA	5	2.58e-01	-2.92e-01	5.43e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH RAS	9	2.59e-01	2.17e-01	5.43e-01
REACTOME APOPTOTIC EXECUTION PHASE	49	2.59e-01	9.33e-02	5.43e-01
REACTOME DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1	9	2.59e-01	2.17e-01	5.43e-01
REACTOME COHESIN LOADING ONTO CHROMATIN	8	2.59e-01	-2.30e-01	5.43e-01
REACTOME GOLGI TO ER RETROGRADE TRANSPORT	132	2.60e-01	5.68e-02	5.43e-01
REACTOME ERYTHROPOIETIN ACTIVATES STAT5	7	2.60e-01	2.46e-01	5.43e-01
REACTOME ERYTHROPOIETIN ACTIVATES RAS	14	2.61e-01	1.74e-01	5.44e-01
REACTOME CRMPS IN SEMA3A SIGNALING	15	2.62e-01	-1.67e-01	5.46e-01
REACTOME SNRNP ASSEMBLY	53	2.63e-01	8.89e-02	5.47e-01
REACTOME EARLY PHASE OF HIV LIFE CYCLE	14	2.66e-01	-1.72e-01	5.52e-01
REACTOME SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER	54	2.66e-01	8.75e-02	5.52e-01
REACTOME SIGNALING BY PTK6	54	2.66e-01	8.75e-02	5.52e-01
REACTOME WAX AND PLASMALOGEN BIOSYNTHESIS	5	2.66e-01	2.87e-01	5.52e-01
REACTOME CELL CELL JUNCTION ORGANIZATION	64	2.67e-01	-8.02e-02	5.52e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	36	2.67e-01	1.07e-01	5.52e-01
REACTOME BETA CATENIN INDEPENDENT WNT SIGNALING	145	2.68e-01	5.33e-02	5.53e-01
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION	250	2.69e-01	4.06e-02	5.55e-01
REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS	15	2.71e-01	-1.64e-01	5.58e-01
REACTOME SIGNALING BY FGFR3	39	2.72e-01	1.02e-01	5.59e-01
REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	20	2.72e-01	1.42e-01	5.59e-01
REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS	312	2.74e-01	-3.60e-02	5.62e-01
REACTOME NFE2L2 REGULATING ANTI OXIDANT DETOXIFICATION ENZYMES	17	2.75e-01	1.53e-01	5.63e-01
REACTOME POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE	25	2.75e-01	1.26e-01	5.63e-01
REACTOME GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION	7	2.76e-01	-2.38e-01	5.64e-01
REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	22	2.77e-01	-1.34e-01	5.64e-01
REACTOME SHC RELATED EVENTS TRIGGERED BY IGF1R	9	2.77e-01	2.09e-01	5.64e-01
REACTOME LIPID PARTICLE ORGANIZATION	6	2.78e-01	-2.56e-01	5.64e-01
REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21	59	2.78e-01	8.17e-02	5.64e-01
REACTOME STAT5 ACTIVATION	7	2.78e-01	2.37e-01	5.64e-01
REACTOME INFECTION WITH MYCOBACTERIUM TUBERCULOSIS	25	2.79e-01	1.25e-01	5.66e-01
REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING	30	2.80e-01	1.14e-01	5.66e-01
REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	22	2.80e-01	1.33e-01	5.66e-01
REACTOME ACTIVATION OF SMO	18	2.82e-01	-1.46e-01	5.69e-01
REACTOME RNA POLYMERASE III CHAIN ELONGATION	18	2.82e-01	1.46e-01	5.69e-01
REACTOME SIGNALING BY NOTCH4	80	2.83e-01	6.95e-02	5.69e-01
REACTOME REGULATION OF RUNX3 EXPRESSION AND ACTIVITY	54	2.83e-01	8.45e-02	5.69e-01
REACTOME RHOU GTPASE CYCLE	37	2.83e-01	1.02e-01	5.69e-01
REACTOME RRNA MODIFICATION IN THE MITOCHONDRION	6	2.84e-01	2.53e-01	5.69e-01
REACTOME HEME SIGNALING	47	2.84e-01	9.04e-02	5.69e-01
REACTOME TRANSCRIPTIONAL REGULATION BY E2F6	32	2.84e-01	1.09e-01	5.69e-01
REACTOME THE ACTIVATION OF ARYLSULFATASES	8	2.84e-01	2.19e-01	5.69e-01
REACTOME MASTL FACILITATES MITOTIC PROGRESSION	10	2.87e-01	1.95e-01	5.73e-01
REACTOME MRNA SPLICING MINOR PATHWAY	49	2.87e-01	8.79e-02	5.73e-01
REACTOME REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION	9	2.89e-01	2.04e-01	5.75e-01
REACTOME DEADENYLATION OF MRNA	25	2.90e-01	1.22e-01	5.77e-01
REACTOME CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA	63	2.91e-01	7.69e-02	5.79e-01
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	53	2.93e-01	8.35e-02	5.81e-01
REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION	20	2.93e-01	1.36e-01	5.81e-01
REACTOME VLDL ASSEMBLY	5	2.94e-01	2.71e-01	5.82e-01
REACTOME PROTEIN METHYLATION	17	2.95e-01	1.47e-01	5.82e-01
REACTOME TNFR2 NON CANONICAL NF KB PATHWAY	96	2.95e-01	6.19e-02	5.82e-01
REACTOME FIBRONECTIN MATRIX FORMATION	6	2.95e-01	2.47e-01	5.83e-01
REACTOME NICOTINAMIDE SALVAGING	19	2.96e-01	-1.39e-01	5.83e-01
REACTOME REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS	7	2.96e-01	2.28e-01	5.83e-01
REACTOME VITAMIN D CALCIFEROL METABOLISM	12	2.97e-01	1.74e-01	5.83e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS	12	2.97e-01	1.74e-01	5.83e-01
REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS	19	2.97e-01	-1.38e-01	5.83e-01
REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS	27	2.98e-01	1.16e-01	5.83e-01
REACTOME REGULATION OF RAS BY GAPS	66	2.99e-01	7.40e-02	5.83e-01
REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS	63	2.99e-01	7.56e-02	5.83e-01
REACTOME RELEASE OF HH NP FROM THE SECRETING CELL	8	2.99e-01	2.12e-01	5.83e-01
REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS	6	2.99e-01	2.45e-01	5.83e-01
REACTOME CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION	24	3.00e-01	1.22e-01	5.83e-01
REACTOME LGI ADAM INTERACTIONS	14	3.00e-01	1.60e-01	5.83e-01
REACTOME SIGNALLING TO ERKS	34	3.02e-01	1.02e-01	5.86e-01
REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS	33	3.02e-01	1.04e-01	5.86e-01
REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA	11	3.02e-01	-1.80e-01	5.86e-01
REACTOME P75NTR SIGNALS VIA NF KB	15	3.03e-01	1.54e-01	5.86e-01
REACTOME NEGATIVE REGULATION OF MAPK PATHWAY	41	3.03e-01	9.30e-02	5.86e-01
REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	11	3.03e-01	1.79e-01	5.86e-01
REACTOME APOPTOTIC FACTOR MEDIATED RESPONSE	19	3.04e-01	1.36e-01	5.86e-01
REACTOME GP1B IX V ACTIVATION SIGNALLING	11	3.04e-01	1.79e-01	5.86e-01
REACTOME CYP2E1 REACTIONS	10	3.04e-01	-1.88e-01	5.86e-01
REACTOME NUCLEOTIDE BIOSYNTHESIS	14	3.05e-01	-1.58e-01	5.86e-01
REACTOME FGFR2 ALTERNATIVE SPLICING	27	3.05e-01	1.14e-01	5.86e-01
REACTOME PROTEIN REPAIR	6	3.06e-01	2.41e-01	5.88e-01
REACTOME INACTIVATION OF CDC42 AND RAC1	8	3.07e-01	-2.09e-01	5.88e-01
REACTOME UPTAKE AND ACTIONS OF BACTERIAL TOXINS	28	3.07e-01	1.12e-01	5.88e-01
REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	46	3.08e-01	8.69e-02	5.88e-01
REACTOME INTERLEUKIN 1 PROCESSING	9	3.10e-01	-1.96e-01	5.91e-01
REACTOME PROPIONYL COA CATABOLISM	5	3.10e-01	2.62e-01	5.91e-01
REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	24	3.10e-01	1.20e-01	5.91e-01
REACTOME REGULATION OF TP53 EXPRESSION AND DEGRADATION	37	3.11e-01	9.63e-02	5.91e-01
REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	12	3.12e-01	-1.68e-01	5.93e-01
REACTOME RHO GTPASES ACTIVATE KTN1	11	3.13e-01	1.76e-01	5.93e-01
REACTOME NUCLEAR PORE COMPLEX NPC DISASSEMBLY	36	3.13e-01	9.71e-02	5.94e-01
REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL	12	3.16e-01	1.67e-01	5.99e-01
REACTOME RHO GTPASES ACTIVATE NADPH OXIDASES	21	3.17e-01	1.26e-01	5.99e-01
REACTOME MITOCHONDRIAL PROTEIN IMPORT	58	3.17e-01	7.59e-02	5.99e-01
REACTOME NONCANONICAL ACTIVATION OF NOTCH3	8	3.17e-01	2.04e-01	5.99e-01
REACTOME NECTIN NECL TRANS HETERODIMERIZATION	7	3.18e-01	-2.18e-01	5.99e-01
REACTOME TRANSPORT OF RCBL WITHIN THE BODY	8	3.19e-01	2.04e-01	6.00e-01
REACTOME ION HOMEOSTASIS	52	3.20e-01	-7.98e-02	6.00e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS	14	3.20e-01	1.54e-01	6.00e-01
REACTOME NOD1 2 SIGNALING PATHWAY	33	3.21e-01	9.99e-02	6.02e-01
REACTOME PYROPTOSIS	27	3.22e-01	1.10e-01	6.03e-01
REACTOME DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS	14	3.23e-01	-1.53e-01	6.03e-01
REACTOME G1 S SPECIFIC TRANSCRIPTION	28	3.23e-01	1.08e-01	6.03e-01
REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING	28	3.23e-01	1.08e-01	6.03e-01
REACTOME METAL ION SLC TRANSPORTERS	23	3.24e-01	1.19e-01	6.03e-01
REACTOME SIGNALING BY ERYTHROPOIETIN	25	3.24e-01	1.14e-01	6.03e-01
REACTOME SEMA4D IN SEMAPHORIN SIGNALING	24	3.25e-01	1.16e-01	6.05e-01
REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	20	3.26e-01	1.27e-01	6.05e-01
REACTOME ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS	87	3.27e-01	6.08e-02	6.05e-01
REACTOME SIGNALING BY ALK IN CANCER	53	3.27e-01	7.79e-02	6.05e-01
REACTOME INTERLEUKIN 2 FAMILY SIGNALING	40	3.27e-01	8.95e-02	6.05e-01
REACTOME DEFECTIVE CHST14 CAUSES EDS MUSCULOCONTRACTURAL TYPE	7	3.27e-01	2.14e-01	6.05e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS	14	3.28e-01	1.51e-01	6.05e-01
REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES	14	3.28e-01	1.51e-01	6.05e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS	7	3.28e-01	2.14e-01	6.05e-01
REACTOME PEXOPHAGY	11	3.29e-01	1.70e-01	6.05e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING	5	3.29e-01	2.52e-01	6.06e-01
REACTOME ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM	12	3.30e-01	1.62e-01	6.06e-01
REACTOME P2Y RECEPTORS	9	3.30e-01	-1.87e-01	6.06e-01
REACTOME ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS	20	3.31e-01	1.26e-01	6.07e-01
REACTOME RHO GTPASES ACTIVATE CIT	19	3.32e-01	1.29e-01	6.08e-01
REACTOME MET ACTIVATES RAS SIGNALING	11	3.33e-01	1.69e-01	6.09e-01
REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	24	3.35e-01	1.14e-01	6.12e-01
REACTOME CALNEXIN CALRETICULIN CYCLE	26	3.35e-01	1.09e-01	6.12e-01
REACTOME GLUTAMATE AND GLUTAMINE METABOLISM	13	3.38e-01	1.54e-01	6.16e-01
REACTOME SODIUM CALCIUM EXCHANGERS	11	3.39e-01	-1.66e-01	6.18e-01
REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	45	3.40e-01	8.22e-02	6.19e-01
REACTOME DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING	61	3.41e-01	7.05e-02	6.20e-01
REACTOME CHL1 INTERACTIONS	9	3.43e-01	-1.83e-01	6.22e-01
REACTOME INITIATION OF NUCLEAR ENVELOPE NE REFORMATION	18	3.43e-01	1.29e-01	6.22e-01
REACTOME REGULATION OF MECP2 EXPRESSION AND ACTIVITY	30	3.44e-01	9.99e-02	6.22e-01
REACTOME COPI MEDIATED ANTEROGRADE TRANSPORT	101	3.44e-01	5.45e-02	6.22e-01
REACTOME TRYPTOPHAN CATABOLISM	14	3.44e-01	-1.46e-01	6.22e-01
REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	29	3.45e-01	1.01e-01	6.22e-01
REACTOME MULTIFUNCTIONAL ANION EXCHANGERS	9	3.45e-01	-1.82e-01	6.22e-01
REACTOME NS1 MEDIATED EFFECTS ON HOST PATHWAYS	41	3.45e-01	8.52e-02	6.22e-01
REACTOME FRUCTOSE METABOLISM	7	3.46e-01	-2.06e-01	6.22e-01
REACTOME TAK1 DEPENDENT IKK AND NF KAPPA B ACTIVATION	41	3.47e-01	8.49e-02	6.23e-01
REACTOME INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS	37	3.48e-01	8.92e-02	6.23e-01
REACTOME EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION	27	3.48e-01	-1.04e-01	6.23e-01
REACTOME UREA CYCLE	9	3.48e-01	-1.81e-01	6.23e-01
REACTOME INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	28	3.48e-01	1.02e-01	6.23e-01
REACTOME SIGNALING BY FGFR	85	3.48e-01	5.88e-02	6.23e-01
REACTOME ALPHA DEFENSINS	6	3.49e-01	2.21e-01	6.24e-01
REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX	9	3.50e-01	1.80e-01	6.24e-01
REACTOME EARLY SARS COV 2 INFECTION EVENTS	34	3.50e-01	9.25e-02	6.25e-01
REACTOME CYTOCHROME C MEDIATED APOPTOTIC RESPONSE	12	3.52e-01	1.55e-01	6.27e-01
REACTOME GABA B RECEPTOR ACTIVATION	43	3.53e-01	-8.19e-02	6.27e-01
REACTOME FREE FATTY ACIDS REGULATE INSULIN SECRETION	10	3.53e-01	-1.70e-01	6.27e-01
REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	30	3.53e-01	9.79e-02	6.27e-01
REACTOME TYPE I HEMIDESMOSOME ASSEMBLY	11	3.55e-01	-1.61e-01	6.30e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH METHYLATION	19	3.57e-01	1.22e-01	6.31e-01
REACTOME SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX	15	3.57e-01	-1.37e-01	6.31e-01
REACTOME RORA ACTIVATES GENE EXPRESSION	17	3.57e-01	1.29e-01	6.31e-01
REACTOME PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1	9	3.57e-01	1.77e-01	6.31e-01
REACTOME DEFECTS IN VITAMIN AND COFACTOR METABOLISM	21	3.58e-01	1.16e-01	6.31e-01
REACTOME SIGNALING BY NOTCH1	69	3.59e-01	6.39e-02	6.32e-01
REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING	25	3.60e-01	1.06e-01	6.33e-01
REACTOME CHOLINE CATABOLISM	6	3.60e-01	2.16e-01	6.33e-01
REACTOME TRIGLYCERIDE CATABOLISM	23	3.61e-01	-1.10e-01	6.33e-01
REACTOME ATTACHMENT AND ENTRY	16	3.64e-01	-1.31e-01	6.38e-01
REACTOME SUMOYLATION OF DNA REPLICATION PROTEINS	46	3.67e-01	7.69e-02	6.43e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS	7	3.67e-01	1.97e-01	6.43e-01
REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	99	3.69e-01	-5.23e-02	6.44e-01
REACTOME RND2 GTPASE CYCLE	42	3.69e-01	8.01e-02	6.44e-01
REACTOME REGULATION BY C FLIP	11	3.69e-01	1.56e-01	6.44e-01
REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	15	3.71e-01	1.33e-01	6.46e-01
REACTOME SYNTHESIS OF UDP N ACETYL GLUCOSAMINE	7	3.71e-01	1.95e-01	6.46e-01
REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY	5	3.72e-01	2.31e-01	6.47e-01
REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	20	3.72e-01	1.15e-01	6.47e-01
REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION	26	3.75e-01	1.01e-01	6.50e-01
REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	17	3.76e-01	1.24e-01	6.51e-01
REACTOME POLYMERASE SWITCHING	13	3.78e-01	1.41e-01	6.54e-01
REACTOME NRCAM INTERACTIONS	6	3.79e-01	-2.08e-01	6.55e-01
REACTOME SIGNALING BY INSULIN RECEPTOR	80	3.80e-01	5.68e-02	6.56e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12	22	3.80e-01	1.08e-01	6.56e-01
REACTOME INWARDLY RECTIFYING K CHANNELS	35	3.80e-01	-8.57e-02	6.56e-01
REACTOME METABOLISM OF STEROIDS	150	3.82e-01	4.13e-02	6.59e-01
REACTOME TRANSPORT AND SYNTHESIS OF PAPS	6	3.83e-01	2.06e-01	6.59e-01
REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	23	3.84e-01	-1.05e-01	6.59e-01
REACTOME NEUREXINS AND NEUROLIGINS	51	3.84e-01	-7.05e-02	6.59e-01
REACTOME PEPTIDE HORMONE METABOLISM	84	3.85e-01	5.49e-02	6.60e-01
REACTOME SIGNALING BY EGFR IN CANCER	25	3.86e-01	1.00e-01	6.61e-01
REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES	29	3.86e-01	9.30e-02	6.61e-01
REACTOME PI3K EVENTS IN ERBB2 SIGNALING	16	3.89e-01	-1.24e-01	6.65e-01
REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER	18	3.90e-01	1.17e-01	6.65e-01
REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	19	3.90e-01	1.14e-01	6.65e-01
REACTOME DEFECTIVE RIPK1 MEDIATED REGULATED NECROSIS	7	3.90e-01	1.87e-01	6.66e-01
REACTOME AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA	54	3.91e-01	6.75e-02	6.66e-01
REACTOME STABILIZATION OF P53	56	3.92e-01	6.62e-02	6.66e-01
REACTOME ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA	5	3.93e-01	2.21e-01	6.67e-01
REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	14	3.93e-01	1.32e-01	6.67e-01
REACTOME FLT3 SIGNALING BY CBL MUTANTS	7	3.93e-01	1.86e-01	6.67e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST	14	3.95e-01	1.31e-01	6.68e-01
REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING	6	3.95e-01	2.00e-01	6.68e-01
REACTOME DISORDERS OF TRANSMEMBRANE TRANSPORTERS	170	3.96e-01	-3.78e-02	6.68e-01
REACTOME NEUROTRANSMITTER RELEASE CYCLE	48	3.96e-01	7.09e-02	6.68e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH CDC42	19	3.96e-01	1.12e-01	6.68e-01
REACTOME KETONE BODY METABOLISM	9	3.96e-01	1.63e-01	6.68e-01
REACTOME ANDROGEN BIOSYNTHESIS	11	3.97e-01	-1.48e-01	6.68e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3	11	3.97e-01	1.47e-01	6.68e-01
REACTOME DNA REPLICATION INITIATION	7	3.99e-01	1.84e-01	6.70e-01
REACTOME SIGNALING BY MST1	5	4.01e-01	2.17e-01	6.71e-01
REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	11	4.01e-01	-1.46e-01	6.71e-01
REACTOME ORC1 REMOVAL FROM CHROMATIN	70	4.01e-01	5.80e-02	6.71e-01
REACTOME NUCLEAR ENVELOPE BREAKDOWN	52	4.02e-01	6.72e-02	6.71e-01
REACTOME ACTIVATION OF RAC1	12	4.02e-01	-1.40e-01	6.71e-01
REACTOME SCAVENGING BY CLASS A RECEPTORS	19	4.02e-01	-1.11e-01	6.71e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES	29	4.03e-01	8.98e-02	6.71e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH PI3K	6	4.03e-01	1.97e-01	6.71e-01
REACTOME PHOSPHORYLATION OF EMI1	6	4.03e-01	1.97e-01	6.71e-01
REACTOME DERMATAN SULFATE BIOSYNTHESIS	10	4.06e-01	1.52e-01	6.75e-01
REACTOME REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO	10	4.06e-01	-1.52e-01	6.75e-01
REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	16	4.08e-01	-1.20e-01	6.77e-01
REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	15	4.09e-01	1.23e-01	6.78e-01
REACTOME NICOTINATE METABOLISM	31	4.09e-01	-8.57e-02	6.78e-01
REACTOME NEGATIVE REGULATION OF NOTCH4 SIGNALING	53	4.12e-01	6.52e-02	6.81e-01
REACTOME LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS	19	4.12e-01	-1.09e-01	6.82e-01
REACTOME COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING	38	4.13e-01	7.67e-02	6.83e-01
REACTOME ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA	9	4.15e-01	1.57e-01	6.84e-01
REACTOME RA BIOSYNTHESIS PATHWAY	22	4.15e-01	1.00e-01	6.84e-01
REACTOME RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES	16	4.15e-01	-1.18e-01	6.84e-01
REACTOME KILLING MECHANISMS	11	4.17e-01	1.41e-01	6.87e-01
REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	10	4.18e-01	-1.48e-01	6.87e-01
REACTOME INTEGRATION OF ENERGY METABOLISM	105	4.19e-01	-4.57e-02	6.87e-01
REACTOME POTASSIUM CHANNELS	102	4.19e-01	-4.63e-02	6.87e-01
REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	22	4.19e-01	9.94e-02	6.87e-01
REACTOME RECYCLING OF BILE ACIDS AND SALTS	18	4.20e-01	-1.10e-01	6.88e-01
REACTOME PENTOSE PHOSPHATE PATHWAY	12	4.21e-01	1.34e-01	6.89e-01
REACTOME PHOSPHOLIPID METABOLISM	201	4.22e-01	3.28e-02	6.90e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	11	4.23e-01	1.40e-01	6.90e-01
REACTOME TELOMERE EXTENSION BY TELOMERASE	22	4.24e-01	9.86e-02	6.91e-01
REACTOME MET ACTIVATES RAP1 AND RAC1	11	4.25e-01	1.39e-01	6.92e-01
REACTOME INTRAFLAGELLAR TRANSPORT	50	4.26e-01	6.51e-02	6.92e-01
REACTOME AZATHIOPRINE ADME	22	4.26e-01	-9.81e-02	6.92e-01
REACTOME TLR3 MEDIATED TICAM1 DEPENDENT PROGRAMMED CELL DEATH	6	4.26e-01	1.88e-01	6.92e-01
REACTOME SARS COV 1 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS	16	4.30e-01	1.14e-01	6.98e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD4	15	4.31e-01	1.17e-01	6.98e-01
REACTOME RHOV GTPASE CYCLE	36	4.31e-01	7.58e-02	6.98e-01
REACTOME GROWTH HORMONE RECEPTOR SIGNALING	24	4.32e-01	9.27e-02	6.98e-01
REACTOME SYNTHESIS OF KETONE BODIES	8	4.32e-01	1.60e-01	6.98e-01
REACTOME POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION	27	4.32e-01	8.73e-02	6.98e-01
REACTOME PD 1 SIGNALING	21	4.34e-01	9.86e-02	7.00e-01
REACTOME VLDL CLEARANCE	6	4.35e-01	1.84e-01	7.01e-01
REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	44	4.36e-01	6.79e-02	7.02e-01
REACTOME EPITHELIAL MESENCHYMAL TRANSITION EMT DURING GASTRULATION	7	4.38e-01	1.69e-01	7.03e-01
REACTOME NEF AND SIGNAL TRANSDUCTION	8	4.38e-01	1.58e-01	7.03e-01
REACTOME FBXW7 MUTANTS AND NOTCH1 IN CANCER	5	4.38e-01	-2.00e-01	7.03e-01
REACTOME METABOLISM OF VITAMINS AND COFACTORS	185	4.38e-01	-3.30e-02	7.03e-01
REACTOME G ALPHA S SIGNALLING EVENTS	155	4.39e-01	-3.60e-02	7.03e-01
REACTOME SYNTHESIS OF 12 EICOSATETRAENOIC ACID DERIVATIVES	7	4.40e-01	1.68e-01	7.04e-01
REACTOME MET INTERACTS WITH TNS PROTEINS	5	4.43e-01	-1.98e-01	7.08e-01
REACTOME BINDING OF TCF LEF CTNNB1 TO TARGET GENE PROMOTERS	8	4.43e-01	1.57e-01	7.08e-01
REACTOME PYRIMIDINE SALVAGE	10	4.44e-01	1.40e-01	7.09e-01
REACTOME DISEASES OF CARBOHYDRATE METABOLISM	31	4.45e-01	-7.93e-02	7.09e-01
REACTOME REGULATION OF NPAS4 MRNA TRANSLATION	9	4.46e-01	1.47e-01	7.10e-01
REACTOME RIBAVIRIN ADME	11	4.47e-01	1.32e-01	7.11e-01
REACTOME MISCELLANEOUS TRANSPORT AND BINDING EVENTS	24	4.48e-01	8.95e-02	7.11e-01
REACTOME CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS	19	4.48e-01	1.00e-01	7.11e-01
REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB	5	4.49e-01	1.96e-01	7.11e-01
REACTOME REGULATION OF PTEN LOCALIZATION	8	4.49e-01	1.55e-01	7.11e-01
REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	51	4.50e-01	6.12e-02	7.12e-01
REACTOME ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA	15	4.50e-01	1.13e-01	7.12e-01
REACTOME CARNITINE METABOLISM	13	4.52e-01	1.21e-01	7.14e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH PI3K	7	4.53e-01	1.64e-01	7.15e-01
REACTOME BIOTIN TRANSPORT AND METABOLISM	10	4.53e-01	-1.37e-01	7.15e-01
REACTOME RSK ACTIVATION	5	4.54e-01	1.94e-01	7.15e-01
REACTOME SIGNALING BY NTRK2 TRKB	25	4.54e-01	8.64e-02	7.15e-01
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	122	4.55e-01	3.92e-02	7.15e-01
REACTOME FASL CD95L SIGNALING	5	4.55e-01	1.93e-01	7.15e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K	12	4.55e-01	1.24e-01	7.15e-01
REACTOME ROLE OF ABL IN ROBO SLIT SIGNALING	8	4.58e-01	1.51e-01	7.18e-01
REACTOME LDL REMODELING	6	4.59e-01	1.75e-01	7.18e-01
REACTOME LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME	11	4.59e-01	1.29e-01	7.18e-01
REACTOME LATE ENDOSOMAL MICROAUTOPHAGY	33	4.59e-01	7.45e-02	7.18e-01
REACTOME NEF MEDIATED CD8 DOWN REGULATION	7	4.60e-01	1.61e-01	7.19e-01
REACTOME SLC TRANSPORTER DISORDERS	94	4.61e-01	-4.40e-02	7.20e-01
REACTOME RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION	22	4.63e-01	9.04e-02	7.22e-01
REACTOME DEX H BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION	7	4.64e-01	1.60e-01	7.23e-01
REACTOME PRE NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM	6	4.65e-01	-1.72e-01	7.23e-01
REACTOME SIGNALING BY FGFR IN DISEASE	62	4.66e-01	5.36e-02	7.23e-01
REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES	77	4.66e-01	-4.81e-02	7.23e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1	20	4.66e-01	9.41e-02	7.23e-01
REACTOME ASSEMBLY OF THE HIV VIRION	16	4.67e-01	1.05e-01	7.23e-01
REACTOME FORMATION OF APOPTOSOME	10	4.67e-01	1.33e-01	7.23e-01
REACTOME CONSTITUTIVE SIGNALING BY EGFRVIII	15	4.68e-01	1.08e-01	7.23e-01
REACTOME EPH EPHRIN MEDIATED REPULSION OF CELLS	50	4.68e-01	5.93e-02	7.23e-01
REACTOME MOLYBDENUM COFACTOR BIOSYNTHESIS	6	4.69e-01	-1.71e-01	7.23e-01
REACTOME SARS COV 2 ACTIVATES MODULATES INNATE AND ADAPTIVE IMMUNE RESPONSES	118	4.69e-01	3.86e-02	7.23e-01
REACTOME REPRESSION OF WNT TARGET GENES	14	4.69e-01	1.12e-01	7.23e-01
REACTOME UNWINDING OF DNA	12	4.70e-01	1.20e-01	7.23e-01
REACTOME CHREBP ACTIVATES METABOLIC GENE EXPRESSION	8	4.70e-01	-1.47e-01	7.23e-01
REACTOME DEGRADATION OF AXIN	54	4.70e-01	5.68e-02	7.23e-01
REACTOME VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS	42	4.72e-01	6.42e-02	7.24e-01
REACTOME CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS	100	4.72e-01	4.16e-02	7.24e-01
REACTOME OVARIAN TUMOR DOMAIN PROTEASES	36	4.73e-01	6.92e-02	7.24e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	14	4.73e-01	1.11e-01	7.24e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR4	26	4.73e-01	8.13e-02	7.24e-01
REACTOME COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC	98	4.76e-01	4.17e-02	7.28e-01
REACTOME P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1	6	4.77e-01	1.68e-01	7.28e-01
REACTOME CD28 DEPENDENT VAV1 PATHWAY	11	4.77e-01	1.24e-01	7.28e-01
REACTOME REGULATION OF NF KAPPA B SIGNALING	17	4.80e-01	9.89e-02	7.32e-01
REACTOMEMATURATION OF SARS COV 1 NUCLEOPROTEIN	11	4.81e-01	1.23e-01	7.32e-01
REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	54	4.81e-01	5.54e-02	7.32e-01
REACTOME NEGATIVE REGULATION OF ACTIVITY OF TFAP2 AP 2 FAMILY TRANSCRIPTION FACTORS	10	4.82e-01	1.28e-01	7.32e-01
REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	45	4.84e-01	-6.02e-02	7.35e-01
REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	160	4.85e-01	3.20e-02	7.35e-01
REACTOME MYOGENESIS	29	4.85e-01	7.49e-02	7.35e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG	7	4.86e-01	1.52e-01	7.35e-01
REACTOME PREVENTION OF PHAGOSOMAL LYSOSOMAL FUSION	9	4.86e-01	1.34e-01	7.35e-01
REACTOME COENZYME A BIOSYNTHESIS	8	4.87e-01	1.42e-01	7.37e-01
REACTOME EXTRA NUCLEAR ESTROGEN SIGNALING	74	4.90e-01	4.64e-02	7.39e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE	8	4.90e-01	1.41e-01	7.39e-01
REACTOME SARS COV 2 MODULATES AUTOPHAGY	11	4.90e-01	1.20e-01	7.39e-01
REACTOME TOXICITY OF BOTULINUM TOXIN TYPE D BOTD	5	4.91e-01	1.78e-01	7.39e-01
REACTOME BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA	5	4.92e-01	1.78e-01	7.40e-01
REACTOME PI3K EVENTS IN ERBB4 SIGNALING	10	4.94e-01	-1.25e-01	7.42e-01
REACTOME REGULATION OF LIPID METABOLISM BY PPARALPHA	115	4.94e-01	3.69e-02	7.42e-01
REACTOME RRNA PROCESSING IN THE MITOCHONDRION	9	4.95e-01	1.31e-01	7.42e-01
REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX	32	4.96e-01	6.96e-02	7.42e-01
REACTOME SYNTHESIS OF GDP MANNOSE	5	4.96e-01	-1.76e-01	7.42e-01
REACTOME ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS	10	4.96e-01	1.24e-01	7.42e-01
REACTOME INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL	14	4.97e-01	-1.05e-01	7.43e-01
REACTOME PI METABOLISM	79	4.99e-01	4.40e-02	7.46e-01
REACTOME SIGNALING BY LEPTIN	11	4.99e-01	1.18e-01	7.46e-01
REACTOME SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS	14	5.01e-01	1.04e-01	7.47e-01
REACTOME PLATELET HOMEOSTASIS	85	5.02e-01	4.22e-02	7.47e-01
REACTOME DEFECTIVE CHSY1 CAUSES TPBS	7	5.02e-01	1.47e-01	7.47e-01
REACTOME ACTIVATION OF RAS IN B CELLS	5	5.02e-01	1.73e-01	7.47e-01
REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	32	5.03e-01	6.83e-02	7.47e-01
REACTOME NERVOUS SYSTEM DEVELOPMENT	552	5.03e-01	1.67e-02	7.47e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS	9	5.04e-01	-1.29e-01	7.47e-01
REACTOME RECEPTOR MEDIATED MITOPHAGY	10	5.04e-01	1.22e-01	7.47e-01
REACTOME ENOS ACTIVATION	11	5.05e-01	1.16e-01	7.47e-01
REACTOME TRAFFICKING OF AMPA RECEPTORS	29	5.05e-01	-7.15e-02	7.47e-01
REACTOME SYNTHESIS OF PA	38	5.06e-01	-6.24e-02	7.47e-01
REACTOME SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL	25	5.07e-01	-7.67e-02	7.48e-01
REACTOME SIGNALING BY BMP	27	5.11e-01	7.31e-02	7.54e-01
REACTOME FGFRL1 MODULATION OF FGFR1 SIGNALING	13	5.11e-01	-1.05e-01	7.54e-01
REACTOME SYNTHESIS OF PG	8	5.12e-01	1.34e-01	7.54e-01
REACTOME OTHER SEMAPHORIN INTERACTIONS	18	5.13e-01	-8.91e-02	7.54e-01
REACTOME MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS	7	5.13e-01	1.43e-01	7.54e-01
REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING	45	5.15e-01	5.62e-02	7.55e-01
REACTOME HIV TRANSCRIPTION INITIATION	43	5.15e-01	5.74e-02	7.55e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH CDK5	6	5.16e-01	1.53e-01	7.56e-01
REACTOME NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10	12	5.17e-01	1.08e-01	7.57e-01
REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	21	5.17e-01	-8.16e-02	7.57e-01
REACTOME PHENYLALANINE METABOLISM	6	5.18e-01	1.52e-01	7.58e-01
REACTOME EFFECTS OF PIP2 HYDROLYSIS	26	5.19e-01	-7.31e-02	7.58e-01
REACTOME DEVELOPMENTAL BIOLOGY	1115	5.20e-01	1.14e-02	7.59e-01
REACTOME THYROXINE BIOSYNTHESIS	10	5.22e-01	-1.17e-01	7.61e-01
REACTOME TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT	18	5.23e-01	8.70e-02	7.62e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS	9	5.23e-01	1.23e-01	7.62e-01
REACTOME FRUCTOSE CATABOLISM	5	5.25e-01	-1.64e-01	7.63e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER	28	5.25e-01	6.93e-02	7.63e-01
REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	19	5.26e-01	8.41e-02	7.63e-01
REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING	33	5.28e-01	6.35e-02	7.65e-01
REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	14	5.28e-01	-9.75e-02	7.65e-01
REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	12	5.29e-01	1.05e-01	7.66e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES	12	5.30e-01	1.05e-01	7.67e-01
REACTOME DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS	25	5.31e-01	7.24e-02	7.68e-01
REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	7	5.34e-01	-1.36e-01	7.68e-01
REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION	35	5.34e-01	6.08e-02	7.68e-01
REACTOME SUMOYLATION OF RNA BINDING PROTEINS	47	5.34e-01	5.25e-02	7.68e-01
REACTOME G ALPHA 12 13 SIGNALLING EVENTS	74	5.34e-01	-4.18e-02	7.68e-01
REACTOME ERKS ARE INACTIVATED	13	5.34e-01	9.96e-02	7.68e-01
REACTOME RHO GTPASES ACTIVATE PAKS	19	5.34e-01	8.24e-02	7.68e-01
REACTOME PIWI INTERACTING RNA PIRNA BIOGENESIS	29	5.36e-01	6.64e-02	7.70e-01
REACTOME SUPPRESSION OF PHAGOSOMAL MATURATION	13	5.39e-01	9.85e-02	7.73e-01
REACTOME TYSND1 CLEAVES PEROXISOMAL PROTEINS	7	5.39e-01	1.34e-01	7.73e-01
REACTOME SHC MEDIATED CASCADE FGFR4	19	5.40e-01	8.13e-02	7.73e-01
REACTOME O LINKED GLYCOSYLATION OF MUCINS	61	5.40e-01	-4.54e-02	7.73e-01
REACTOME INDUCTION OF CELL CELL FUSION	12	5.41e-01	-1.02e-01	7.74e-01
REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING	32	5.44e-01	6.20e-02	7.74e-01
REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION	74	5.44e-01	4.08e-02	7.74e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH RAS	8	5.44e-01	1.24e-01	7.74e-01
REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	93	5.44e-01	3.64e-02	7.74e-01
REACTOME MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION	15	5.44e-01	9.04e-02	7.74e-01
REACTOME TRIGLYCERIDE METABOLISM	35	5.45e-01	-5.92e-02	7.74e-01
REACTOME STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES	16	5.45e-01	-8.74e-02	7.74e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR3	24	5.46e-01	7.13e-02	7.75e-01
REACTOME ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE	9	5.49e-01	1.15e-01	7.79e-01
REACTOME COMPLEX I BIOGENESIS	49	5.54e-01	4.88e-02	7.86e-01
REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING	29	5.55e-01	-6.33e-02	7.86e-01
REACTOME PTK6 PROMOTES HIF1A STABILIZATION	6	5.56e-01	1.39e-01	7.86e-01
REACTOME DEATH RECEPTOR SIGNALING	143	5.56e-01	2.85e-02	7.86e-01
REACTOME PHASE 1 INACTIVATION OF FAST NA CHANNELS	6	5.57e-01	-1.39e-01	7.86e-01
REACTOME DISEASES OF BASE EXCISION REPAIR	5	5.57e-01	1.52e-01	7.86e-01
REACTOME GLUTATHIONE CONJUGATION	33	5.57e-01	5.91e-02	7.86e-01
REACTOME IRAK1 RECRUITS IKK COMPLEX	12	5.58e-01	9.77e-02	7.86e-01
REACTOME REGULATION OF PTEN MRNA TRANSLATION	9	5.59e-01	1.13e-01	7.86e-01
REACTOME LRR FLII INTERACTING PROTEIN 1 LRRFIP1 ACTIVATES TYPE I IFN PRODUCTION	5	5.59e-01	1.51e-01	7.86e-01
REACTOME METABOLISM OF COFACTORS	19	5.59e-01	7.74e-02	7.86e-01
REACTOME G1 S DNA DAMAGE CHECKPOINTS	67	5.60e-01	4.11e-02	7.86e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	25	5.61e-01	6.72e-02	7.86e-01
REACTOME GLYCOLYSIS	70	5.61e-01	4.02e-02	7.86e-01
REACTOME ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING	9	5.61e-01	-1.12e-01	7.86e-01
REACTOME CROSS PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS PHAGOSOMES	6	5.64e-01	-1.36e-01	7.88e-01
REACTOME IRS ACTIVATION	5	5.64e-01	-1.49e-01	7.88e-01
REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	11	5.65e-01	1.00e-01	7.88e-01
REACTOME NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION	193	5.65e-01	-2.40e-02	7.88e-01
REACTOME EPHA MEDIATED GROWTH CONE COLLAPSE	29	5.65e-01	6.17e-02	7.88e-01
REACTOME GRB7 EVENTS IN ERBB2 SIGNALING	5	5.65e-01	1.48e-01	7.88e-01
REACTOME DISSOLUTION OF FIBRIN CLOT	13	5.67e-01	9.17e-02	7.89e-01
REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R	52	5.67e-01	4.59e-02	7.89e-01
REACTOME METABOLISM OF PORPHYRINS	26	5.68e-01	6.47e-02	7.90e-01
REACTOME FATTY ACIDS BOUND TO GPR40 FFAR1 REGULATE INSULIN SECRETION	8	5.71e-01	-1.16e-01	7.91e-01
REACTOME CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION	11	5.71e-01	9.87e-02	7.91e-01
REACTOME SERINE BIOSYNTHESIS	9	5.71e-01	1.09e-01	7.91e-01
REACTOME CELL CELL COMMUNICATION	126	5.71e-01	-2.92e-02	7.91e-01
REACTOME SIGNALING BY PDGF	57	5.71e-01	-4.34e-02	7.91e-01
REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV 1 INFECTION	5	5.72e-01	-1.46e-01	7.91e-01
REACTOME ASPARTATE AND ASPARAGINE METABOLISM	11	5.72e-01	9.83e-02	7.91e-01
REACTOME G PROTEIN BETA GAMMA SIGNALLING	30	5.74e-01	5.93e-02	7.93e-01
REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	76	5.75e-01	3.72e-02	7.93e-01
REACTOME TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX	10	5.75e-01	1.02e-01	7.93e-01
REACTOME G2 M DNA REPLICATION CHECKPOINT	5	5.76e-01	1.44e-01	7.93e-01
REACTOME CHAPERONE MEDIATED AUTOPHAGY	20	5.76e-01	-7.22e-02	7.93e-01
REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS	14	5.77e-01	8.61e-02	7.93e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS	9	5.79e-01	1.07e-01	7.95e-01
REACTOME SIGNALING BY RNF43 MUTANTS	8	5.79e-01	-1.13e-01	7.95e-01
REACTOME SIGNALING BY FGFR1	49	5.80e-01	4.57e-02	7.95e-01
REACTOME FORMATION OF PARAXIAL MESODERM	22	5.81e-01	6.79e-02	7.97e-01
REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	15	5.82e-01	-8.20e-02	7.98e-01
REACTOME BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS	10	5.84e-01	1.00e-01	7.99e-01
REACTOME SOS MEDIATED SIGNALLING	7	5.85e-01	1.19e-01	7.99e-01
REACTOME TRP CHANNELS	27	5.89e-01	-6.01e-02	8.04e-01
REACTOME GLUCOSE METABOLISM	90	5.89e-01	3.29e-02	8.04e-01
REACTOME TRAF6 MEDIATED NF KB ACTIVATION	24	5.91e-01	6.33e-02	8.06e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2	17	5.92e-01	-7.52e-02	8.06e-01
REACTOME RUNX2 REGULATES BONE DEVELOPMENT	29	5.94e-01	5.72e-02	8.08e-01
REACTOME MET ACTIVATES PTPN11	5	5.94e-01	1.38e-01	8.08e-01
REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY	26	5.95e-01	-6.02e-02	8.08e-01
REACTOME ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS	5	5.95e-01	-1.37e-01	8.08e-01
REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	13	5.96e-01	-8.50e-02	8.08e-01
REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	15	5.97e-01	-7.89e-02	8.08e-01
REACTOME SIGNALING BY HEDGEHOG	148	5.97e-01	2.52e-02	8.08e-01
REACTOME MET ACTIVATES PI3K AKT SIGNALING	6	5.98e-01	1.24e-01	8.08e-01
REACTOME GLUCOCORTICOID BIOSYNTHESIS	10	5.98e-01	-9.62e-02	8.08e-01
REACTOME SIGNALING BY ERBB2 ECD MUTANTS	16	5.99e-01	7.60e-02	8.08e-01
REACTOME ZINC TRANSPORTERS	15	5.99e-01	7.85e-02	8.08e-01
REACTOME ORGANIC CATION TRANSPORT	10	6.00e-01	-9.59e-02	8.09e-01
REACTOME CA DEPENDENT EVENTS	36	6.01e-01	-5.03e-02	8.10e-01
REACTOME GLYCEROPHOSPHOLIPID CATABOLISM	7	6.01e-01	-1.14e-01	8.10e-01
REACTOME MRNA EDITING C TO U CONVERSION	8	6.02e-01	-1.07e-01	8.10e-01
REACTOME REGULATION OF INSULIN SECRETION	77	6.02e-01	-3.44e-02	8.10e-01
REACTOME DNA DAMAGE REVERSAL	8	6.02e-01	-1.06e-01	8.10e-01
REACTOME DARPP 32 EVENTS	24	6.03e-01	6.13e-02	8.10e-01
REACTOME GAP JUNCTION DEGRADATION	12	6.04e-01	8.65e-02	8.10e-01
REACTOME RHOQ GTPASE CYCLE	57	6.05e-01	-3.96e-02	8.10e-01
REACTOME NEURONAL SYSTEM	388	6.05e-01	-1.53e-02	8.10e-01
REACTOME AMINO ACIDS REGULATE MTORC1	53	6.05e-01	4.11e-02	8.10e-01
REACTOME RAF ACTIVATION	33	6.07e-01	5.17e-02	8.12e-01
REACTOME NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS	22	6.08e-01	6.31e-02	8.13e-01
REACTOME PROLACTIN RECEPTOR SIGNALING	15	6.09e-01	-7.63e-02	8.13e-01
REACTOME FGFR2B LIGAND BINDING AND ACTIVATION	10	6.12e-01	-9.26e-02	8.15e-01
REACTOME SIGNALING BY NOTCH2	32	6.12e-01	5.18e-02	8.15e-01
REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4	33	6.12e-01	5.10e-02	8.15e-01
REACTOME ACYL CHAIN REMODELING OF CL	5	6.14e-01	-1.30e-01	8.17e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS	15	6.14e-01	-7.51e-02	8.17e-01
REACTOME ADRENOCEPTORS	9	6.16e-01	9.64e-02	8.19e-01
REACTOME HSF1 DEPENDENT TRANSACTIVATION	37	6.17e-01	4.75e-02	8.19e-01
REACTOME HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS	9	6.18e-01	9.61e-02	8.19e-01
REACTOME BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA	5	6.22e-01	1.27e-01	8.24e-01
REACTOME METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION	15	6.24e-01	7.31e-02	8.26e-01
REACTOME PKA ACTIVATION IN GLUCAGON SIGNALLING	17	6.25e-01	-6.85e-02	8.27e-01
REACTOME REGULATION OF SIGNALING BY CBL	22	6.27e-01	5.99e-02	8.29e-01
REACTOME ENDOGENOUS STEROLS	26	6.30e-01	-5.47e-02	8.29e-01
REACTOME RUNX2 REGULATES CHONDROCYTE MATURATION	5	6.30e-01	1.24e-01	8.29e-01
REACTOME REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA	15	6.30e-01	7.18e-02	8.29e-01
REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	123	6.30e-01	2.51e-02	8.29e-01
REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES	21	6.30e-01	6.07e-02	8.29e-01
REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	35	6.30e-01	4.70e-02	8.29e-01
REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	14	6.31e-01	7.41e-02	8.29e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS	5	6.31e-01	1.24e-01	8.29e-01
REACTOME SHC MEDIATED CASCADE FGFR3	17	6.32e-01	6.72e-02	8.29e-01
REACTOME G PROTEIN ACTIVATION	24	6.35e-01	5.60e-02	8.33e-01
REACTOME PREGNENOLONE BIOSYNTHESIS	12	6.36e-01	7.89e-02	8.33e-01
REACTOME G2 PHASE	5	6.38e-01	1.22e-01	8.35e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1	25	6.39e-01	5.42e-02	8.36e-01
REACTOME SUMOYLATION OF DNA METHYLATION PROTEINS	16	6.41e-01	6.74e-02	8.37e-01
REACTOME REGULATION OF PTEN STABILITY AND ACTIVITY	67	6.41e-01	3.29e-02	8.37e-01
REACTOME SUMOYLATION OF SUMOYLATION PROTEINS	35	6.42e-01	4.54e-02	8.37e-01
REACTOME MRNA CAPPING	28	6.43e-01	5.07e-02	8.37e-01
REACTOME PI 3K CASCADE FGFR4	19	6.43e-01	6.15e-02	8.37e-01
REACTOME LINOLEIC ACID LA METABOLISM	7	6.43e-01	1.01e-01	8.37e-01
REACTOME DEFECTIVE CSF2RB CAUSES SMDP5	7	6.43e-01	1.01e-01	8.37e-01
REACTOME RESPONSE OF MTB TO PHAGOCYTOSIS	22	6.44e-01	5.69e-02	8.38e-01
REACTOME CD209 DC SIGN SIGNALING	20	6.45e-01	5.95e-02	8.38e-01
REACTOME ACTIVATION OF TRKA RECEPTORS	6	6.46e-01	-1.08e-01	8.38e-01
REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS	21	6.48e-01	-5.76e-02	8.39e-01
REACTOME FRS MEDIATED FGFR4 SIGNALING	21	6.48e-01	5.76e-02	8.39e-01
REACTOME SHC1 EVENTS IN EGFR SIGNALING	14	6.49e-01	7.04e-02	8.39e-01
REACTOME SUMOYLATION OF IMMUNE RESPONSE PROTEINS	10	6.49e-01	8.31e-02	8.39e-01
REACTOME PRE NOTCH PROCESSING IN GOLGI	18	6.49e-01	-6.19e-02	8.39e-01
REACTOME SARS COV 2 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS	12	6.50e-01	7.57e-02	8.39e-01
REACTOME NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	19	6.50e-01	-6.01e-02	8.39e-01
REACTOME SMAC XIAP REGULATED APOPTOTIC RESPONSE	7	6.51e-01	9.87e-02	8.39e-01
REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL	13	6.52e-01	7.22e-02	8.39e-01
REACTOME GLUCAGON TYPE LIGAND RECEPTORS	32	6.53e-01	-4.60e-02	8.39e-01
REACTOME G PROTEIN MEDIATED EVENTS	53	6.54e-01	-3.56e-02	8.39e-01
REACTOME SUMO IS PROTEOLYTICALLY PROCESSED	6	6.54e-01	1.06e-01	8.39e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE	20	6.54e-01	5.79e-02	8.39e-01
REACTOME ABC TRANSPORTER DISORDERS	76	6.54e-01	-2.97e-02	8.39e-01
REACTOME ACETYLCHOLINE REGULATES INSULIN SECRETION	10	6.54e-01	-8.18e-02	8.39e-01
REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	11	6.55e-01	-7.78e-02	8.39e-01
REACTOME MTORC1 MEDIATED SIGNALLING	23	6.56e-01	5.37e-02	8.40e-01
REACTOME ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY	10	6.59e-01	8.06e-02	8.42e-01
REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS	60	6.59e-01	3.29e-02	8.42e-01
REACTOME DISEASES OF MISMATCH REPAIR MMR	5	6.59e-01	-1.14e-01	8.42e-01
REACTOME TRANSPORT OF FATTY ACIDS	8	6.60e-01	-8.99e-02	8.42e-01
REACTOME TNF SIGNALING	54	6.60e-01	3.46e-02	8.42e-01
REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	35	6.60e-01	4.29e-02	8.42e-01
REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	16	6.61e-01	-6.33e-02	8.42e-01
REACTOME LYSINE CATABOLISM	12	6.61e-01	7.30e-02	8.42e-01
REACTOME ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN	13	6.62e-01	6.99e-02	8.42e-01
REACTOME DOPAMINE RECEPTORS	5	6.63e-01	1.13e-01	8.42e-01
REACTOME NETRIN MEDIATED REPULSION SIGNALS	8	6.63e-01	8.89e-02	8.42e-01
REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	11	6.65e-01	-7.53e-02	8.44e-01
REACTOME RECYCLING OF EIF2 GDP	7	6.66e-01	9.43e-02	8.44e-01
REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	14	6.67e-01	-6.65e-02	8.45e-01
REACTOME PTK6 EXPRESSION	5	6.69e-01	1.11e-01	8.45e-01
REACTOME TNFR1 INDUCED PROAPOPTOTIC SIGNALING	23	6.69e-01	5.15e-02	8.45e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FYN	7	6.70e-01	-9.31e-02	8.45e-01
REACTOME REGULATION OF NPAS4 GENE EXPRESSION	13	6.70e-01	6.83e-02	8.45e-01
REACTOME ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT	23	6.70e-01	5.13e-02	8.45e-01
REACTOME VIRAL MESSENGER RNA SYNTHESIS	44	6.70e-01	3.71e-02	8.45e-01
REACTOME SODIUM PROTON EXCHANGERS	7	6.72e-01	-9.23e-02	8.47e-01
REACTOME CATION COUPLED CHLORIDE COTRANSPORTERS	7	6.73e-01	-9.22e-02	8.47e-01
REACTOME MATURATION OF SARS COV 2 NUCLEOPROTEIN	15	6.74e-01	6.27e-02	8.48e-01
REACTOME JOSEPHIN DOMAIN DUBS	11	6.76e-01	7.28e-02	8.50e-01
REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	17	6.81e-01	-5.76e-02	8.55e-01
REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	21	6.81e-01	-5.18e-02	8.55e-01
REACTOME SENSING OF DNA DOUBLE STRAND BREAKS	6	6.84e-01	9.59e-02	8.58e-01
REACTOME METABOLISM OF CARBOHYDRATES	279	6.89e-01	-1.39e-02	8.63e-01
REACTOME DSCAM INTERACTIONS	11	6.89e-01	6.97e-02	8.63e-01
REACTOME ELASTIC FIBRE FORMATION	44	6.89e-01	-3.48e-02	8.63e-01
REACTOME MIRO GTPASE CYCLE	8	6.90e-01	8.13e-02	8.63e-01
REACTOME NR1H2 AND NR1H3 MEDIATED SIGNALING	46	6.90e-01	-3.39e-02	8.63e-01
REACTOME ROBO RECEPTORS BIND AKAP5	9	6.91e-01	7.64e-02	8.63e-01
REACTOME INTEGRATION OF PROVIRUS	9	6.92e-01	-7.64e-02	8.63e-01
REACTOME SIGNALING BY VEGF	102	6.92e-01	2.27e-02	8.63e-01
REACTOME CAMK IV MEDIATED PHOSPHORYLATION OF CREB	10	6.93e-01	7.20e-02	8.64e-01
REACTOME CA2 ACTIVATED K CHANNELS	9	6.94e-01	-7.58e-02	8.64e-01
REACTOME CHYLOMICRON CLEARANCE	5	6.96e-01	-1.01e-01	8.65e-01
REACTOME PROLONGED ERK ACTIVATION EVENTS	14	6.97e-01	-6.02e-02	8.65e-01
REACTOME CHYLOMICRON ASSEMBLY	10	6.97e-01	-7.12e-02	8.65e-01
REACTOME PP2A MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS	6	6.97e-01	9.18e-02	8.65e-01
REACTOME INTRA GOLGI TRAFFIC	43	6.98e-01	3.42e-02	8.66e-01
REACTOME RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY	14	7.00e-01	5.95e-02	8.66e-01
REACTOME NRAGE SIGNALS DEATH THROUGH JNK	53	7.00e-01	-3.06e-02	8.66e-01
REACTOME VXPX CARGO TARGETING TO CILIUM	20	7.00e-01	-4.98e-02	8.66e-01
REACTOME PYRIMIDINE CATABOLISM	12	7.01e-01	6.40e-02	8.67e-01
REACTOME FLT3 SIGNALING THROUGH SRC FAMILY KINASES	6	7.02e-01	9.02e-02	8.67e-01
REACTOME NEUROTRANSMITTER CLEARANCE	9	7.04e-01	-7.32e-02	8.68e-01
REACTOME FOLDING OF ACTIN BY CCT TRIC	10	7.04e-01	6.94e-02	8.68e-01
REACTOME FATTY ACYL COA BIOSYNTHESIS	36	7.04e-01	3.66e-02	8.68e-01
REACTOME SIGNALING BY MRAS COMPLEX MUTANTS	7	7.05e-01	-8.26e-02	8.68e-01
REACTOME TRNA MODIFICATION IN THE MITOCHONDRION	8	7.06e-01	7.72e-02	8.68e-01
REACTOME GLYCOGEN METABOLISM	22	7.07e-01	-4.64e-02	8.69e-01
REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	30	7.09e-01	3.94e-02	8.71e-01
REACTOME RAC1 GTPASE CYCLE	172	7.09e-01	-1.65e-02	8.71e-01
REACTOME PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING	5	7.13e-01	9.49e-02	8.75e-01
REACTOME PECAM1 INTERACTIONS	12	7.16e-01	6.07e-02	8.78e-01
REACTOME UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION	19	7.18e-01	-4.79e-02	8.80e-01
REACTOME RHOB GTPASE CYCLE	67	7.22e-01	2.52e-02	8.83e-01
REACTOME TRANSPORT OF NUCLEOTIDE SUGARS	8	7.22e-01	7.27e-02	8.83e-01
REACTOME OAS ANTIVIRAL RESPONSE	8	7.23e-01	-7.24e-02	8.83e-01
REACTOME SYNTHESIS OF PI	5	7.23e-01	-9.14e-02	8.83e-01
REACTOME PEPTIDE HORMONE BIOSYNTHESIS	13	7.24e-01	-5.65e-02	8.83e-01
REACTOME BASIGIN INTERACTIONS	24	7.24e-01	4.16e-02	8.83e-01
REACTOME SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA PHE	6	7.24e-01	8.31e-02	8.83e-01
REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF	17	7.26e-01	4.91e-02	8.84e-01
REACTOME METABOLISM OF STEROID HORMONES	35	7.26e-01	-3.42e-02	8.84e-01
REACTOME ARYL HYDROCARBON RECEPTOR SIGNALLING	6	7.29e-01	-8.17e-02	8.87e-01
REACTOME TYROSINE CATABOLISM	5	7.30e-01	-8.91e-02	8.87e-01
REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ	6	7.33e-01	8.06e-02	8.89e-01
REACTOME TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS	26	7.33e-01	-3.87e-02	8.89e-01
REACTOME MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS	17	7.33e-01	4.77e-02	8.89e-01
REACTOME SHC1 EVENTS IN ERBB2 SIGNALING	22	7.34e-01	-4.19e-02	8.89e-01
REACTOME ONCOGENIC MAPK SIGNALING	79	7.35e-01	2.21e-02	8.89e-01
REACTOME MUSCARINIC ACETYLCHOLINE RECEPTORS	5	7.35e-01	8.74e-02	8.89e-01
REACTOME INTEGRIN SIGNALING	27	7.36e-01	-3.75e-02	8.90e-01
REACTOME HYALURONAN BIOSYNTHESIS AND EXPORT	5	7.38e-01	-8.65e-02	8.91e-01
REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	32	7.39e-01	3.40e-02	8.93e-01
REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	13	7.40e-01	5.31e-02	8.93e-01
REACTOME REGULATION OF IFNA IFNB SIGNALING	23	7.45e-01	-3.92e-02	8.98e-01
REACTOME AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY	8	7.45e-01	-6.64e-02	8.98e-01
REACTOME SUPPRESSION OF APOPTOSIS	7	7.47e-01	-7.05e-02	8.98e-01
REACTOME CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER	25	7.47e-01	3.72e-02	8.98e-01
REACTOME IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN	5	7.48e-01	8.31e-02	8.98e-01
REACTOME PI 3K CASCADE FGFR3	17	7.48e-01	4.51e-02	8.98e-01
REACTOME RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA	7	7.49e-01	6.99e-02	8.98e-01
REACTOME FRS MEDIATED FGFR3 SIGNALING	19	7.49e-01	4.24e-02	8.98e-01
REACTOME ACTIVATION OF PPARGC1A PGC 1ALPHA BY PHOSPHORYLATION	10	7.50e-01	-5.83e-02	8.99e-01
REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	19	7.50e-01	-4.22e-02	8.99e-01
REACTOME HDL REMODELING	10	7.52e-01	5.78e-02	8.99e-01
REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS	17	7.52e-01	-4.43e-02	8.99e-01
REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	14	7.52e-01	4.88e-02	8.99e-01
REACTOME FGFR1C LIGAND BINDING AND ACTIVATION	11	7.55e-01	5.43e-02	9.02e-01
REACTOME REGULATION OF GENE EXPRESSION IN ENDOCRINE COMMITTED NEUROG3 PROGENITOR CELLS	5	7.57e-01	7.99e-02	9.02e-01
REACTOME SCAVENGING BY CLASS F RECEPTORS	6	7.57e-01	7.28e-02	9.02e-01
REACTOME SIGNALING BY WNT IN CANCER	32	7.57e-01	-3.16e-02	9.02e-01
REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	10	7.58e-01	5.64e-02	9.02e-01
REACTOME INTERLEUKIN RECEPTOR SHC SIGNALING	24	7.58e-01	3.63e-02	9.02e-01
REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES	37	7.59e-01	-2.91e-02	9.03e-01
REACTOME METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS	122	7.60e-01	1.60e-02	9.03e-01
REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	17	7.61e-01	4.26e-02	9.03e-01
REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	30	7.64e-01	-3.16e-02	9.07e-01
REACTOME METHYLATION	14	7.66e-01	-4.60e-02	9.07e-01
REACTOME SEMAPHORIN INTERACTIONS	61	7.66e-01	2.20e-02	9.07e-01
REACTOME RHOA GTPASE CYCLE	142	7.67e-01	-1.44e-02	9.07e-01
REACTOME EGFR INTERACTS WITH PHOSPHOLIPASE C GAMMA	9	7.67e-01	-5.69e-02	9.07e-01
REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	14	7.68e-01	-4.55e-02	9.07e-01
REACTOME GAP JUNCTION TRAFFICKING AND REGULATION	49	7.69e-01	2.43e-02	9.07e-01
REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	48	7.69e-01	-2.45e-02	9.07e-01
REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION	6	7.69e-01	6.91e-02	9.07e-01
REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	24	7.70e-01	-3.44e-02	9.07e-01
REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	28	7.70e-01	-3.19e-02	9.07e-01
REACTOME ERK MAPK TARGETS	20	7.71e-01	3.76e-02	9.07e-01
REACTOME ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY	5	7.74e-01	7.42e-02	9.10e-01
REACTOME DEFECTIVE F9 ACTIVATION	5	7.76e-01	7.35e-02	9.12e-01
REACTOME LDL CLEARANCE	19	7.77e-01	3.76e-02	9.12e-01
REACTOME TIGHT JUNCTION INTERACTIONS	29	7.77e-01	3.04e-02	9.12e-01
REACTOME UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN	6	7.80e-01	6.59e-02	9.14e-01
REACTOME SIGNALING BY NOTCH3	48	7.81e-01	2.32e-02	9.14e-01
REACTOME RUNX3 REGULATES WNT SIGNALING	8	7.81e-01	5.69e-02	9.14e-01
REACTOME GLYCOGEN STORAGE DISEASES	15	7.82e-01	-4.12e-02	9.15e-01
REACTOME DEGRADATION OF GLI1 BY THE PROTEASOME	59	7.84e-01	2.06e-02	9.17e-01
REACTOME NEGATIVE REGULATION OF MET ACTIVITY	20	7.86e-01	3.51e-02	9.18e-01
REACTOME NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS	25	7.86e-01	3.13e-02	9.18e-01
REACTOME CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE	49	7.86e-01	2.24e-02	9.18e-01
REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX	36	7.87e-01	2.60e-02	9.18e-01
REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK	17	7.89e-01	-3.74e-02	9.19e-01
REACTOME DISINHIBITION OF SNARE FORMATION	5	7.90e-01	6.89e-02	9.19e-01
REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION	12	7.90e-01	-4.44e-02	9.19e-01
REACTOME SIALIC ACID METABOLISM	33	7.91e-01	2.67e-02	9.19e-01
REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	10	7.91e-01	4.83e-02	9.20e-01
REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING	12	7.93e-01	4.37e-02	9.21e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING	6	7.94e-01	6.14e-02	9.22e-01
REACTOME SEROTONIN RECEPTORS	11	7.95e-01	4.53e-02	9.22e-01
REACTOME SIGNALING BY ERBB4	57	7.96e-01	1.98e-02	9.22e-01
REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	26	7.98e-01	2.90e-02	9.22e-01
REACTOME FGFR3 LIGAND BINDING AND ACTIVATION	12	7.98e-01	-4.26e-02	9.22e-01
REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	122	7.98e-01	-1.34e-02	9.22e-01
REACTOME MATURATION OF PROTEIN 3A	9	7.99e-01	4.90e-02	9.22e-01
REACTOME ALK MUTANTS BIND TKIS	12	7.99e-01	4.25e-02	9.22e-01
REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION	11	7.99e-01	4.43e-02	9.22e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR2	29	8.00e-01	2.72e-02	9.22e-01
REACTOME PTK6 REGULATES CELL CYCLE	6	8.00e-01	-5.97e-02	9.22e-01
REACTOME LIPOPHAGY	9	8.00e-01	4.87e-02	9.22e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2	13	8.02e-01	4.02e-02	9.22e-01
REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	62	8.02e-01	1.84e-02	9.22e-01
REACTOME RUNX3 REGULATES P14 ARF	10	8.03e-01	4.56e-02	9.22e-01
REACTOME SUMOYLATION OF UBIQUITINYLATION PROTEINS	39	8.03e-01	2.31e-02	9.22e-01
REACTOME RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS	9	8.03e-01	4.80e-02	9.22e-01
REACTOME CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY	12	8.04e-01	4.13e-02	9.22e-01
REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION	42	8.05e-01	2.20e-02	9.22e-01
REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	15	8.05e-01	3.68e-02	9.22e-01
REACTOME FCGR3A MEDIATED IL10 SYNTHESIS	36	8.07e-01	2.36e-02	9.22e-01
REACTOME PHENYLALANINE AND TYROSINE METABOLISM	11	8.07e-01	4.26e-02	9.22e-01
REACTOME ACYL CHAIN REMODELING OF DAG AND TAG	5	8.07e-01	6.31e-02	9.22e-01
REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	16	8.11e-01	3.45e-02	9.26e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY DVL INTERACTING PROTEINS	5	8.11e-01	-6.16e-02	9.26e-01
REACTOME NTRK2 ACTIVATES RAC1	5	8.12e-01	-6.15e-02	9.26e-01
REACTOME DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA	77	8.12e-01	1.56e-02	9.26e-01
REACTOME SUMO IS CONJUGATED TO E1 UBA2 SAE1	5	8.15e-01	6.05e-02	9.28e-01
REACTOME GLUCONEOGENESIS	33	8.17e-01	-2.33e-02	9.29e-01
REACTOME TRIGLYCERIDE BIOSYNTHESIS	12	8.17e-01	3.86e-02	9.29e-01
REACTOME BETA OXIDATION OF PRISTANOYL COA	9	8.17e-01	-4.45e-02	9.29e-01
REACTOME PROCESSING OF SMDT1	16	8.18e-01	-3.32e-02	9.29e-01
REACTOME CS DS DEGRADATION	12	8.19e-01	-3.82e-02	9.29e-01
REACTOME SYNTHESIS OF PIPS AT THE ER MEMBRANE	5	8.21e-01	-5.85e-02	9.30e-01
REACTOME RAS PROCESSING	22	8.21e-01	2.79e-02	9.30e-01
REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	11	8.21e-01	-3.93e-02	9.30e-01
REACTOME INTERLEUKIN 10 SIGNALING	43	8.22e-01	-1.99e-02	9.30e-01
REACTOME MITOCHONDRIAL UNCOUPLING	5	8.25e-01	5.72e-02	9.33e-01
REACTOME DEGRADATION OF DVL	56	8.26e-01	1.70e-02	9.33e-01
REACTOME DOWNREGULATION OF ERBB4 SIGNALING	9	8.27e-01	4.21e-02	9.33e-01
REACTOME EGFR DOWNREGULATION	30	8.27e-01	2.30e-02	9.33e-01
REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	46	8.27e-01	1.86e-02	9.33e-01
REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	16	8.28e-01	3.15e-02	9.33e-01
REACTOME GAP JUNCTION ASSEMBLY	36	8.29e-01	2.08e-02	9.33e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING	25	8.29e-01	2.49e-02	9.33e-01
REACTOME AQUAPORIN MEDIATED TRANSPORT	51	8.30e-01	1.74e-02	9.33e-01
REACTOME KINESINS	59	8.31e-01	1.61e-02	9.34e-01
REACTOME CDC42 GTPASE CYCLE	144	8.37e-01	-9.94e-03	9.39e-01
REACTOME ER QUALITY CONTROL COMPARTMENT ERQC	21	8.37e-01	2.59e-02	9.39e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS	11	8.37e-01	-3.57e-02	9.39e-01
REACTOME MITOCHONDRIAL CALCIUM ION TRANSPORT	23	8.39e-01	2.45e-02	9.40e-01
REACTOME DEPOLYMERISATION OF THE NUCLEAR LAMINA	14	8.39e-01	3.14e-02	9.40e-01
REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	18	8.39e-01	2.76e-02	9.40e-01
REACTOME ARACHIDONATE PRODUCTION FROM DAG	5	8.40e-01	-5.20e-02	9.40e-01
REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	13	8.41e-01	-3.22e-02	9.40e-01
REACTOME RUNX3 REGULATES YAP1 MEDIATED TRANSCRIPTION	8	8.42e-01	-4.06e-02	9.41e-01
REACTOME PLATELET SENSITIZATION BY LDL	17	8.44e-01	2.76e-02	9.42e-01
REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	69	8.44e-01	1.37e-02	9.42e-01
REACTOME IRS MEDIATED SIGNALLING	47	8.46e-01	1.64e-02	9.42e-01
REACTOME G ALPHA Z SIGNALLING EVENTS	48	8.46e-01	-1.62e-02	9.42e-01
REACTOME HEDGEHOG ON STATE	85	8.47e-01	-1.21e-02	9.43e-01
REACTOME RND3 GTPASE CYCLE	41	8.47e-01	1.74e-02	9.43e-01
REACTOME IRF3 MEDIATED INDUCTION OF TYPE I IFN	13	8.53e-01	-2.97e-02	9.48e-01
REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	23	8.53e-01	2.23e-02	9.48e-01
REACTOME PI3K AKT SIGNALING IN CANCER	103	8.55e-01	1.04e-02	9.48e-01
REACTOME GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	34	8.55e-01	1.81e-02	9.48e-01
REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	12	8.55e-01	3.05e-02	9.48e-01
REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	111	8.57e-01	9.93e-03	9.49e-01
REACTOME INLA MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS	9	8.57e-01	-3.47e-02	9.49e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE	11	8.58e-01	3.11e-02	9.49e-01
REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION	32	8.59e-01	-1.82e-02	9.49e-01
REACTOME CALCITONIN LIKE LIGAND RECEPTORS	10	8.59e-01	3.24e-02	9.49e-01
REACTOME PASSIVE TRANSPORT BY AQUAPORINS	13	8.59e-01	-2.84e-02	9.49e-01
REACTOME DAG AND IP3 SIGNALING	40	8.61e-01	-1.60e-02	9.49e-01
REACTOME PROCESSING AND ACTIVATION OF SUMO	10	8.61e-01	3.20e-02	9.49e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS	15	8.62e-01	2.58e-02	9.50e-01
REACTOME RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION	8	8.63e-01	3.53e-02	9.50e-01
REACTOME ESTABLISHMENT OF SISTER CHROMATID COHESION	9	8.67e-01	-3.24e-02	9.54e-01
REACTOME NADE MODULATES DEATH SIGNALLING	5	8.70e-01	4.21e-02	9.57e-01
REACTOME SEROTONIN NEUROTRANSMITTER RELEASE CYCLE	17	8.71e-01	-2.27e-02	9.57e-01
REACTOME SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS	43	8.72e-01	-1.42e-02	9.57e-01
REACTOME METABOLISM OF FOLATE AND PTERINES	17	8.72e-01	2.25e-02	9.57e-01
REACTOME REGULATION OF BACH1 ACTIVITY	11	8.73e-01	2.78e-02	9.58e-01
REACTOME IKBA VARIANT LEADS TO EDA ID	6	8.74e-01	3.73e-02	9.58e-01
REACTOME ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS	17	8.75e-01	2.21e-02	9.58e-01
REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS	12	8.76e-01	2.61e-02	9.58e-01
REACTOME INTERLEUKIN 1 FAMILY SIGNALING	146	8.76e-01	7.48e-03	9.58e-01
REACTOME MET RECEPTOR ACTIVATION	6	8.78e-01	3.63e-02	9.59e-01
REACTOME TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY	30	8.78e-01	1.62e-02	9.59e-01
REACTOME POST TRANSCRIPTIONAL SILENCING BY SMALL RNAS	7	8.79e-01	3.32e-02	9.60e-01
REACTOME DISEASES ASSOCIATED WITH SURFACTANT METABOLISM	9	8.80e-01	-2.91e-02	9.60e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1	31	8.81e-01	1.55e-02	9.60e-01
REACTOME ARMS MEDIATED ACTIVATION	7	8.82e-01	-3.25e-02	9.60e-01
REACTOME FGFR3B LIGAND BINDING AND ACTIVATION	7	8.82e-01	3.24e-02	9.60e-01
REACTOME TELOMERE C STRAND SYNTHESIS INITIATION	12	8.83e-01	2.46e-02	9.60e-01
REACTOME PROTON COUPLED MONOCARBOXYLATE TRANSPORT	6	8.83e-01	-3.47e-02	9.60e-01
REACTOME DOWNREGULATION OF ERBB2 SIGNALING	29	8.83e-01	-1.58e-02	9.60e-01
REACTOME SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL	8	8.85e-01	-2.94e-02	9.60e-01
REACTOME HYALURONAN METABOLISM	17	8.86e-01	-2.01e-02	9.60e-01
REACTOME NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY	6	8.86e-01	3.38e-02	9.60e-01
REACTOME RHOC GTPASE CYCLE	71	8.86e-01	-9.84e-03	9.60e-01
REACTOME NETRIN 1 SIGNALING	49	8.86e-01	-1.18e-02	9.60e-01
REACTOME DRUG MEDIATED INHIBITION OF CDK4 CDK6 ACTIVITY	5	8.90e-01	3.58e-02	9.62e-01
REACTOME RUNX3 REGULATES BCL2L11 BIM TRANSCRIPTION	5	8.90e-01	3.58e-02	9.62e-01
REACTOME ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY	10	8.91e-01	-2.50e-02	9.63e-01
REACTOME SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER	15	8.91e-01	-2.04e-02	9.63e-01
REACTOME RHOJ GTPASE CYCLE	51	8.92e-01	1.10e-02	9.63e-01
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES	255	8.93e-01	-4.89e-03	9.63e-01
REACTOME ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS	24	8.94e-01	-1.57e-02	9.63e-01
REACTOME FCGR ACTIVATION	11	8.94e-01	2.31e-02	9.63e-01
REACTOME RUNX3 REGULATES NOTCH SIGNALING	13	8.95e-01	-2.12e-02	9.63e-01
REACTOME AMINE LIGAND BINDING RECEPTORS	40	8.95e-01	-1.21e-02	9.63e-01
REACTOME FGFR2 LIGAND BINDING AND ACTIVATION	19	8.96e-01	-1.73e-02	9.64e-01
REACTOME GPER1 SIGNALING	45	8.97e-01	1.11e-02	9.64e-01
REACTOME ESTROGEN BIOSYNTHESIS	6	8.98e-01	-3.01e-02	9.64e-01
REACTOME HEDGEHOG OFF STATE	111	8.99e-01	6.98e-03	9.64e-01
REACTOME RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES TREGS	9	9.00e-01	2.41e-02	9.64e-01
REACTOME COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM	21	9.00e-01	1.58e-02	9.64e-01
REACTOME SMALL INTERFERING RNA SIRNA BIOGENESIS	9	9.00e-01	2.41e-02	9.64e-01
REACTOME RHOBTB3 ATPASE CYCLE	8	9.03e-01	-2.48e-02	9.66e-01
REACTOME SIGNALING BY FGFR2 IIIA TM	19	9.04e-01	1.61e-02	9.66e-01
REACTOME RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION	6	9.04e-01	2.85e-02	9.66e-01
REACTOME SIGNALING BY LRP5 MUTANTS	6	9.04e-01	-2.83e-02	9.66e-01
REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	15	9.05e-01	-1.77e-02	9.67e-01
REACTOME PLATELET AGGREGATION PLUG FORMATION	39	9.06e-01	1.09e-02	9.67e-01
REACTOME MICRORNA MIRNA BIOGENESIS	25	9.07e-01	1.35e-02	9.67e-01
REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	32	9.08e-01	-1.18e-02	9.67e-01
REACTOME NOSTRIN MEDIATED ENOS TRAFFICKING	5	9.08e-01	2.98e-02	9.67e-01
REACTOME FATTY ACID METABOLISM	170	9.09e-01	5.08e-03	9.67e-01
REACTOME LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX	5	9.11e-01	2.90e-02	9.67e-01
REACTOME SYNAPTIC ADHESION LIKE MOLECULES	19	9.11e-01	1.48e-02	9.67e-01
REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	13	9.11e-01	1.78e-02	9.67e-01
REACTOME INTERLEUKIN 20 FAMILY SIGNALING	25	9.11e-01	1.28e-02	9.67e-01
REACTOME TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7	12	9.12e-01	-1.85e-02	9.67e-01
REACTOME EPHRIN SIGNALING	17	9.13e-01	1.53e-02	9.67e-01
REACTOME HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS	7	9.14e-01	2.37e-02	9.67e-01
REACTOME RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR	19	9.14e-01	-1.43e-02	9.67e-01
REACTOME UBIQUINOL BIOSYNTHESIS	8	9.15e-01	2.18e-02	9.67e-01
REACTOME SUMO IS TRANSFERRED FROM E1 TO E2 UBE2I UBC9	7	9.15e-01	-2.33e-02	9.67e-01
REACTOME PI 3K CASCADE FGFR1	21	9.20e-01	-1.27e-02	9.72e-01
REACTOME NGF INDEPENDANT TRKA ACTIVATION	5	9.21e-01	-2.55e-02	9.72e-01
REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS	63	9.22e-01	-7.14e-03	9.72e-01
REACTOME NEUROFASCIN INTERACTIONS	6	9.22e-01	2.31e-02	9.72e-01
REACTOME INOSITOL PHOSPHATE METABOLISM	45	9.24e-01	8.24e-03	9.73e-01
REACTOME ATTACHMENT OF GPI ANCHOR TO UPAR	7	9.24e-01	2.07e-02	9.73e-01
REACTOME VOLTAGE GATED POTASSIUM CHANNELS	42	9.25e-01	8.41e-03	9.73e-01
REACTOME MITOTIC TELOPHASE CYTOKINESIS	11	9.26e-01	-1.63e-02	9.74e-01
REACTOME SIGNAL TRANSDUCTION BY L1	20	9.27e-01	1.19e-02	9.74e-01
REACTOME SIGNALING BY MAPK MUTANTS	6	9.27e-01	-2.17e-02	9.74e-01
REACTOME PI3K AKT ACTIVATION	9	9.30e-01	1.70e-02	9.75e-01
REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	89	9.30e-01	5.40e-03	9.75e-01
REACTOME SYNTHESIS OF LIPOXINS LX	6	9.30e-01	-2.06e-02	9.75e-01
REACTOME INSULIN RECEPTOR SIGNALLING CASCADE	53	9.32e-01	6.80e-03	9.76e-01
REACTOME CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND	9	9.34e-01	-1.59e-02	9.78e-01
REACTOME GLYCOGEN SYNTHESIS	13	9.35e-01	-1.31e-02	9.78e-01
REACTOME FRS MEDIATED FGFR1 SIGNALING	23	9.35e-01	-9.86e-03	9.78e-01
REACTOME COBALAMIN CBL METABOLISM	7	9.39e-01	1.68e-02	9.80e-01
REACTOME SIGNALING BY NOTCH1 T 7 9 NOTCH1 M1580 K2555 TRANSLOCATION MUTANT	7	9.39e-01	1.67e-02	9.80e-01
REACTOME OTHER INTERLEUKIN SIGNALING	24	9.40e-01	8.88e-03	9.80e-01
REACTOME METHIONINE SALVAGE PATHWAY	6	9.40e-01	1.77e-02	9.80e-01
REACTOME INTERLEUKIN 37 SIGNALING	20	9.40e-01	-9.65e-03	9.80e-01
REACTOME POLB DEPENDENT LONG PATCH BASE EXCISION REPAIR	8	9.41e-01	1.52e-02	9.80e-01
REACTOME NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	11	9.43e-01	-1.25e-02	9.82e-01
REACTOME VITAMIN B1 THIAMIN METABOLISM	5	9.43e-01	1.84e-02	9.82e-01
REACTOME 2 LTR CIRCLE FORMATION	7	9.47e-01	-1.44e-02	9.85e-01
REACTOME NEPHRIN FAMILY INTERACTIONS	22	9.49e-01	-7.86e-03	9.86e-01
REACTOME DEFECTIVE CHST3 CAUSES SEDCJD	7	9.51e-01	-1.35e-02	9.87e-01
REACTOME MRNA EDITING	10	9.52e-01	-1.10e-02	9.87e-01
REACTOME MTOR SIGNALLING	40	9.52e-01	-5.47e-03	9.87e-01
REACTOME LONG TERM POTENTIATION	22	9.52e-01	-7.35e-03	9.87e-01
REACTOME REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS	15	9.54e-01	8.69e-03	9.88e-01
REACTOME PI 3K CASCADE FGFR2	22	9.54e-01	-7.10e-03	9.88e-01
REACTOME REGULATION OF BETA CELL DEVELOPMENT	41	9.58e-01	-4.80e-03	9.90e-01
REACTOME SIGNALLING TO P38 VIA RIT AND RIN	5	9.58e-01	-1.35e-02	9.90e-01
REACTOME MAP2K AND MAPK ACTIVATION	38	9.59e-01	-4.82e-03	9.90e-01
REACTOME LIGAND RECEPTOR INTERACTIONS	8	9.59e-01	1.04e-02	9.90e-01
REACTOME TACHYKININ RECEPTORS BIND TACHYKININS	5	9.61e-01	1.25e-02	9.90e-01
REACTOME DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B	7	9.62e-01	-1.05e-02	9.90e-01
REACTOME NEF MEDIATED CD4 DOWN REGULATION	9	9.62e-01	-9.25e-03	9.90e-01
REACTOME SURFACTANT METABOLISM	28	9.62e-01	5.19e-03	9.90e-01
REACTOME HYALURONAN UPTAKE AND DEGRADATION	12	9.64e-01	7.55e-03	9.90e-01
REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	11	9.65e-01	7.67e-03	9.90e-01
REACTOME ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS	41	9.65e-01	3.97e-03	9.90e-01
REACTOME DEFECTS IN BIOTIN BTN METABOLISM	8	9.65e-01	8.92e-03	9.90e-01
REACTOME SIGNALING BY ERBB2	50	9.66e-01	3.44e-03	9.90e-01
REACTOME SHC MEDIATED CASCADE FGFR1	21	9.67e-01	5.19e-03	9.90e-01
REACTOME FRS MEDIATED FGFR2 SIGNALING	24	9.67e-01	-4.84e-03	9.90e-01
REACTOME RUNX3 REGULATES CDKN1A TRANSCRIPTION	7	9.67e-01	-8.90e-03	9.90e-01
REACTOME CA2 PATHWAY	62	9.68e-01	-2.99e-03	9.90e-01
REACTOME MYOCLONIC EPILEPSY OF LAFORA	9	9.68e-01	7.67e-03	9.90e-01
REACTOME NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	24	9.68e-01	-4.68e-03	9.90e-01
REACTOME SIGNAL ATTENUATION	10	9.69e-01	-7.19e-03	9.90e-01
REACTOME REGULATION OF NPAS4 GENE TRANSCRIPTION	5	9.70e-01	9.56e-03	9.92e-01
REACTOME REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS	11	9.71e-01	6.30e-03	9.92e-01
REACTOME GDP FUCOSE BIOSYNTHESIS	6	9.72e-01	8.35e-03	9.92e-01
REACTOME RHOF GTPASE CYCLE	40	9.72e-01	-3.18e-03	9.92e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS	8	9.73e-01	-6.78e-03	9.92e-01
REACTOME NUCLEAR SIGNALING BY ERBB4	32	9.75e-01	3.18e-03	9.92e-01
REACTOME CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN	45	9.75e-01	-2.67e-03	9.92e-01
REACTOME SIGNALING BY FGFR4 IN DISEASE	11	9.76e-01	5.27e-03	9.92e-01
REACTOME PHASE 3 RAPID REPOLARISATION	8	9.76e-01	6.13e-03	9.92e-01
REACTOME UPTAKE AND FUNCTION OF ANTHRAX TOXINS	11	9.77e-01	-4.98e-03	9.93e-01
REACTOME PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS	21	9.79e-01	-3.29e-03	9.94e-01
REACTOME BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA	5	9.79e-01	6.64e-03	9.94e-01
REACTOME RHOG GTPASE CYCLE	71	9.81e-01	-1.66e-03	9.94e-01
REACTOME OPIOID SIGNALLING	89	9.81e-01	1.48e-03	9.94e-01
REACTOME CREB PHOSPHORYLATION	6	9.81e-01	5.53e-03	9.94e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR4	14	9.83e-01	3.33e-03	9.95e-01
REACTOME BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA	6	9.84e-01	-4.76e-03	9.95e-01
REACTOME SIGNALING BY FGFR2 IN DISEASE	42	9.84e-01	-1.76e-03	9.95e-01
REACTOME GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION	30	9.86e-01	-1.79e-03	9.97e-01
REACTOME VITAMIN B2 RIBOFLAVIN METABOLISM	7	9.87e-01	-3.60e-03	9.97e-01
REACTOME REDUCTION OF CYTOSOLIC CA LEVELS	11	9.89e-01	2.49e-03	9.97e-01
REACTOME MET RECEPTOR RECYCLING	10	9.89e-01	2.55e-03	9.97e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE	74	9.89e-01	-9.16e-04	9.97e-01
REACTOME ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING	23	9.90e-01	-1.57e-03	9.97e-01
REACTOME SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION	8	9.91e-01	2.19e-03	9.98e-01
REACTOME REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM	11	9.92e-01	-1.84e-03	9.98e-01
REACTOME SIGNALING BY ERBB2 IN CANCER	26	9.93e-01	-1.03e-03	9.98e-01
REACTOME GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION	42	9.93e-01	-7.91e-04	9.98e-01
REACTOME CALCINEURIN ACTIVATES NFAT	9	9.94e-01	1.45e-03	9.98e-01
REACTOME EGFR TRANSACTIVATION BY GASTRIN	9	9.94e-01	1.38e-03	9.98e-01
REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER	77	9.95e-01	-4.42e-04	9.98e-01
REACTOME RHOD GTPASE CYCLE	49	9.97e-01	-3.10e-04	9.99e-01
REACTOME RAP1 SIGNALLING	16	9.97e-01	-5.23e-04	9.99e-01
REACTOME ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION	28	9.98e-01	2.99e-04	9.99e-01
REACTOME NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION	20	9.99e-01	-2.32e-04	9.99e-01
REACTOME METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES	33	1.00e+00	1.38e-05	1.00e+00

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Detailed Gene set reports

REACTOME_SENSORY_PERCEPTION

REACTOME_SENSORY_PERCEPTION

	1581
set	REACTOME_SENSORY_PERCEPTION
setSize	555
pANOVA	6.28e-35
s.dist	-0.306
p.adjustANOVA	1.03e-31

Top enriched genes

Top 20 genes

GeneID	Gene Rank
OR2V1	-10486
OR10J3	-10447
OR5AC2	-10429
OR51A7	-10428
OR52L1	-10401
OR10P1	-10392
OR52N2	-10390
OR51D1	-10384
OR2T3	-10382
OR10Z1	-10365
OR4D6	-10360
OR56B4	-10331
OR10A3	-10325
OR10K2	-10320
OR56B1	-10276
OR13C2	-10266
APOA4	-10240
OR2D3	-10231
PDE6G	-10229
OR10H4	-10196

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
OR2V1	-10486.0
OR10J3	-10447.0
OR5AC2	-10429.0
OR51A7	-10428.0
OR52L1	-10401.0
OR10P1	-10392.0
OR52N2	-10390.0
OR51D1	-10384.0
OR2T3	-10382.0
OR10Z1	-10365.0
OR4D6	-10360.0
OR56B4	-10331.0
OR10A3	-10325.0
OR10K2	-10320.0
OR56B1	-10276.0
OR13C2	-10266.0
APOA4	-10240.0
OR2D3	-10231.0
PDE6G	-10229.0
OR10H4	-10196.0
RBP3	-10195.0
OR1G1	-10191.0
APOC3	-10181.0
OR9Q2	-10163.0
GNB3	-10145.0
OR51G2	-10129.0
OR4M1	-10116.0
OR52E4	-10108.0
OR8A1	-10082.0
GRXCR2	-10070.0
OR13C8	-10057.0
OR8H3	-10033.0
OR52I1	-10020.0
OR5A1	-10013.0
OR8D2	-9971.0
OR51G1	-9951.0
TAS2R41	-9916.0
OR7D4	-9888.0
OR2T12	-9866.0
OR2A5	-9852.0
OR51F1	-9849.0
OR5K1	-9837.0
USH1C	-9834.0
TAS2R43	-9811.0
OR6C65	-9806.0
OR9G1	-9777.5
OR9G9	-9777.5
OR10G8	-9772.0
RHO	-9731.0
OR1E1	-9722.0
OR10C1	-9721.0
OR5T1	-9709.0
OR51L1	-9708.0
OR10S1	-9687.0
OR2G2	-9686.0
RPE65	-9642.0
OR10V1	-9634.0
OR4D11	-9622.0
OR6C6	-9605.0
OR5F1	-9577.0
TAS2R10	-9576.0
SCNN1D	-9563.0
OR51V1	-9554.0
RDH5	-9520.0
OR13A1	-9517.0
OR51S1	-9503.0
OR6T1	-9483.0
OR4K5	-9482.0
AKR1C4	-9465.0
CNGA4	-9459.0
OR52I2	-9439.0
OR4D10	-9421.0
KCNMB1	-9385.0
OR12D3	-9374.0
AKR1C1	-9344.0
OR1S1	-9326.0
OR2T8	-9304.0
OR5D16	-9295.0
GUCA1B	-9281.0
SCN3A	-9276.0
OR5P3	-9258.0
STRA6	-9231.0
OR6C2	-9223.0
OR10A7	-9213.0
OR8J3	-9204.0
OR1A1	-9170.0
OR10K1	-9134.0
OR2AK2	-9092.0
OR2H1	-9080.0
OR52A1	-9054.0
TTR	-9047.0
OR11H6	-9032.0
OR6S1	-8999.0
TAS2R3	-8991.0
OR5V1	-8977.0
OR51E2	-8949.0
OR6C75	-8934.0
OR11A1	-8906.0
CNGB1	-8888.0
TAS2R39	-8885.0
OR5M9	-8837.0
PNLIP	-8830.0
OR4E2	-8824.0
OR52N1	-8775.0
XIRP2	-8773.0
OR2W3	-8747.0
OR12D2	-8723.0
OR10G7	-8712.0
RTP2	-8696.0
OR2G6	-8693.0
OR1M1	-8692.0
OR2M5	-8680.0
OR51B2	-8636.0
OR52H1	-8631.0
OR3A3	-8630.0
OR51I1	-8624.0
CTBP2	-8623.0
OR6B1	-8595.0
OR56A3	-8572.0
OR52B2	-8557.0
BSN	-8544.0
OR4L1	-8538.0
OR8B12	-8530.0
SDC1	-8515.0
OR5L2	-8495.0
RLBP1	-8469.0
OR13C4	-8436.0
CALHM3	-8419.0
OR4K15	-8418.0
OR5H15	-8416.0
MYO15A	-8393.0
OR51B5	-8367.0
GUCA1A	-8326.0
OR2S2	-8311.0
OR2B2	-8278.0
OR3A1	-8245.0
OR5AS1	-8201.0
APOA2	-8190.0
RDH12	-8167.0
OR14C36	-8162.0
OR14J1	-8142.0
OR5T2	-8140.0
OR5A2	-8136.0
TWF2	-8117.0
OR1C1	-8116.0
OR2B3	-8111.0
OR8K1	-8103.0
SLC24A1	-8086.0
OR2L2	-8051.0
OR52M1	-8042.0
AGRN	-8013.0
OR2A2	-7988.0
OR7A17	-7957.0
OR10H1	-7897.0
OR5K2	-7868.0
ATP2B1	-7866.0
TAS2R40	-7802.0
GRK1	-7794.0
OR9A4	-7780.0
OR10J1	-7779.0
OTOF	-7766.0
OR52K2	-7752.0
SCN2B	-7734.0
OR1A2	-7731.0
OR8B4	-7712.0
OR6K6	-7708.0
OR10G2	-7692.0
TAS2R46	-7667.0
OR52J3	-7625.0
OR5AP2	-7623.0
OR6F1	-7602.0
OR2K2	-7594.0
STRC	-7572.0
OR56A4	-7568.0
RBP2	-7531.0
OR52A5	-7513.0
OR2A14	-7476.0
OR14I1	-7470.0
OR10J5	-7450.0
OR51F2	-7447.0
OR9G4	-7409.0
OR8D4	-7375.0
OR51B4	-7339.0
OR51A2	-7222.0
OR2C3	-7209.0
OR5AR1	-7194.0
OR8J1	-7176.0
OR13F1	-7160.0
ADCY3	-7084.0
OR2H2	-7056.0
OR10A4	-7032.0
CLIC5	-7013.0
OR2AP1	-7004.0
OR1E2	-6993.0
OR1B1	-6982.0
HSPG2	-6970.0
OR11H4	-6930.0
OR10H3	-6926.0
OR2M4	-6908.0
OR2T1	-6904.0
OR5M11	-6894.0
OR10A2	-6869.0
OR8B8	-6853.0
OR4N2	-6786.0
PCDH15	-6737.0
OR10X1	-6726.0
OR2B11	-6646.0
OR51Q1	-6632.0
APOM	-6631.0
REEP1	-6630.0
GUCA1C	-6608.0
OR6K2	-6597.0
EPB41L1	-6572.0
OR5T3	-6547.0
SNAP25	-6543.0
PDE6B	-6538.0
OR2AG1	-6461.0
TAS2R50	-6451.0
OR5L1	-6386.0
OR1L1	-6362.0
OR4K2	-6242.0
OR2L3	-6182.0
OR6Y1	-6145.0
KCNJ2	-6129.0
OR8S1	-6052.0
OR5M1	-5998.0
OR7G2	-5994.0
MYO3B	-5991.0
OR52W1	-5986.0
EPB41L3	-5947.0
OR1L6	-5820.0
KCNMA1	-5788.0
OR4D9	-5718.0
LRP12	-5673.0
TRPM5	-5628.0
LRAT	-5621.0
PLB1	-5608.0
OR2AT4	-5606.0
OR8K5	-5601.0
OR2M3	-5595.0
OR51I2	-5581.0
OR8U3	-5578.0
TPRN	-5539.0
CACNA2D2	-5499.0
TMC2	-5399.0
ABCA4	-5398.0
OR2C1	-5333.0
TAS1R3	-5322.0
OR6C70	-5276.0
CHRNA9	-5258.0
OR4N5	-5253.0
GNGT1	-5244.0
LRP8	-5217.0
OR6C76	-5214.0
OR1S2	-5212.0
GNAT3	-5199.0
CDH23	-5195.0
OR4D1	-5180.0
OR6X1	-5177.0
SCN2A	-5156.0
OR2D2	-5152.0
OTOGL	-5107.0
OR11G2	-5097.0
GPC6	-5079.0
OR7D2	-5044.0
OR7C1	-5005.0
SCNN1A	-4987.0
TAS1R2	-4959.0
OR51T1	-4940.0
ATP2B2	-4917.0
OR8G1	-4829.0
GRXCR1	-4785.0
RTP1	-4782.0
OR10H2	-4769.0
MYO7A	-4762.0
OR10G9	-4744.0
LRP1	-4684.0
TAS2R1	-4628.0
OR1F1	-4580.0
OR2F2	-4577.0
OR10Q1	-4576.0
APOB	-4556.0
APOE	-4456.0
OR2M2	-4415.0
GPC2	-4376.0
TAS2R31	-4364.0
PLS1	-4275.0
OPN1SW	-4273.0
OTOP1	-4233.0
SCNN1G	-4216.0
ANO2	-4191.0
CACNA1D	-4162.0
OR56A1	-4066.0
OR52R1	-4023.0
CNGA1	-3962.0
HSD17B6	-3958.0
OTOG	-3937.0
OR13C9	-3855.0
CHRNA10	-3851.0
GRK7	-3766.0
OR5B2	-3730.0
SCN9A	-3639.0
PCLO	-3572.0
OR5K4	-3506.0
OR5D14	-3432.0
LRP10	-3306.0
GPC5	-3299.0
OR4A15	-3287.0
SCN4B	-3250.0
OR6B2	-3247.0
TRPM4	-3219.0
OR10A5	-3154.5
GRM1	-3140.0
OR13C3	-3098.0
TAS2R13	-3089.0
OR8I2	-3064.0
AKR1C3	-3027.0
OR1L4	-2992.0
DNAJC5	-2970.0
CLPS	-2902.0
TAS2R7	-2853.0
OR2T27	-2822.0
OR4A47	-2652.0
OR9A2	-2589.0
OR2Y1	-2588.0
OR10AD1	-2506.0
SDR9C7	-2502.0
OR4D5	-2487.0
CAPZA2	-2480.0
OR1K1	-2449.0
TAS2R4	-2445.0
RDH16	-2416.0
OR6B3	-2353.0
OR4C6	-2258.0
OR2M7	-2254.0
TMC1	-2214.0
GPC1	-2085.0
SDC2	-2040.0
OR1Q1	-1999.0
OR4K1	-1929.0
LDLR	-1898.0
OR6C1	-1845.0
SCNN1B	-1774.0
OR7A5	-1744.0
KCNQ4	-1675.0
OR4C16	-1620.0
OR1I1	-1612.0
CAMKMT	-1591.0
PRKCQ	-1576.0
FSCN2	-1462.0
OR6V1	-1434.0
CAPZA1	-1417.0
BCO1	-1404.0
GNAT1	-1401.0
OR6M1	-1356.0
EPS8	-1345.0
OR52E8	-1227.0
BCO2	-1100.0
WHRN	-1091.0
OR2AG2	-1026.0
SAG	-1020.0
OR4K13	-1007.0
OR2F1	-981.0
RCVRN	-953.0
OR4C15	-888.0
OR6P1	-794.0
OR2L13	-755.0
OR51E1	-738.0
RGS9	-730.0
GRM4	-654.0
OR5J2	-647.0
GNAL	-592.0
OR6N2	-585.0
OR8G5	-514.0
CALHM1	-498.0
OR4K14	-492.0
CAPZB	-478.0
METAP2	-402.0
GNB1	-354.0
FNTB	-306.0
ITPR3	-266.0
NMT1	-235.0
OR5B21	-218.0
PDE6A	-140.0
OR5B12	-112.0
OR8K3	-107.0
EBF1	-80.0
SLC26A5	9.0
SPTBN1	93.0
OR5W2	192.0
OR6C4	309.0
OR6K3	352.0
OR2V2	485.0
OR9I1	585.0
OR5K3	712.0
CYP4V2	883.0
FNTA	893.0
SLC17A8	913.0
NMT2	974.0
CACNB2	975.0
OR5I1	1028.0
AKR1B10	1051.0
PLCB2	1082.0
OR7G1	1190.0
TWF1	1269.0
OR2W1	1290.0
CABP1	1292.0
DHRS9	1350.0
TAS2R20	1369.0
CABP2	1442.0
OR13J1	1467.0
OR6C68	1514.0
OR1L3	1518.0
ACTB	1540.0
OR5D18	1565.0
TAS2R8	1692.0
OR5AN1	1835.0
OR2G3	1866.0
RDH8	1903.0
OR11L1	1930.0
EZR	2045.0
OR52B6	2059.0
ESPNL	2075.0
OR1D2	2109.0
OR4K17	2123.0
OR2T6	2124.0
OR8U8	2143.0
TRIOBP	2196.0
GSN	2217.0
OR5B17	2223.0
PRKCA	2239.0
GRK4	2353.0
TAS2R5	2435.0
OR8U1	2458.0
OR8H1	2541.0
OR52E6	2579.0
PJVK	2806.0
OR14A16	2827.0
OR4S1	2910.0
LRP2	2920.0
OR2T11	3013.0
OR10G4	3056.0
OR9Q1	3168.0
SPTAN1	3207.0
METAP1	3394.0
GPIHBP1	3475.0
OR8B2	3503.0
OR5H2	3509.0
OR8D1	3531.0
MYO3A	3689.0
OR51B6	3731.0
OR2AE1	3765.0
OR6N1	3770.0
OR52K1	3773.0
OR4C45	3798.0
OR52E2	3868.0
OR5H6	3956.0
OR4F6	3998.0
OR2T4	4021.0
OR5B3	4146.0
OR10A6	4175.0
OR6A2	4398.0
CALM1	4537.0
APOC2	4757.0
APOA1	4789.0
RBP1	5005.0
GNB5	5118.0
MYH9	5185.0
GUCY2D	5220.0
OR4F15	5235.0
NAPEPLD	5248.0
SDC4	5314.0
SDC3	5389.0
OR4D2	5678.0
OR7E24	5687.0
OR2T33	5697.0
TAS1R1	5919.0
OR7C2	5950.0
OR2Z1	5974.0
TAS2R14	5982.0
OR4A16	6162.0
RETSAT	6254.0
OR6C74	6264.0
OR5M3	6335.0
OR10H5	6425.0
OR10AG1	6427.0
KCNN2	6489.0
OR51M1	6514.0
OR4X2	6592.0
OR4A5	6638.0
OR5M8	6649.0
LHFPL5	6776.0
OR2L5	6902.0
OR4C12	6979.0
ESPN	7176.0
EPS8L2	7205.0
RDH10	7218.0
OR10G3	7243.0
OR13D1	7341.0
OR5AK2	7357.0
TAS2R16	7490.0
TMIE	7498.0
OR4C3	7660.0
OR2A12	7667.0
CIB2	7750.0
OR2J2	7799.0
OR1L8	7905.0
LPL	7994.0
DHRS3	8011.0
RBP4	8110.0
OR7G3	8451.0
LRRC52	8467.0
SCN1B	8471.0
RDX	8537.0
OR5AU1	8579.0
GNG13	8769.0
MYO1C	8817.0
OR2B6	8866.0
OR2L8	8897.0
OR52D1	8903.0
HSD17B1	8929.0
LHX2	8981.0
OR1J2	9051.0
OR9K2	9072.0
OR6C3	9100.0
OR4X1	9151.0
USH1G	9164.0
OR5P2	9223.0
RIPOR2	9279.0
LDB1	9297.0
RDH11	9325.0
RAB3A	9566.0
TAS2R38	9634.0
RGS9BP	9772.0
OR4B1	9953.0
ACTG1	9958.0
OR3A2	10127.0
OR13G1	10280.0
OR5M10	10290.0
OR5D13	10310.0
OR10W1	10459.0
OR1J4	10529.0
OR1N1	10569.0
OR7A10	10584.0
OR10T2	10636.0
STX1A	10693.0
OR5C1	10747.0
VAMP2	10831.0
TAS2R30	10863.0
OR4C46	10956.0
OR56A5	11075.0
OR1N2	11138.0
OR5H1	11402.0
OR1J1	11421.0
OR6Q1	11447.0

---

REACTOME_OLFACTORY_SIGNALING_PATHWAY

REACTOME_OLFACTORY_SIGNALING_PATHWAY

	628
set	REACTOME_OLFACTORY_SIGNALING_PATHWAY
setSize	348
pANOVA	3.07e-29
s.dist	-0.35
p.adjustANOVA	2.52e-26

Top enriched genes

Top 20 genes

GeneID	Gene Rank
OR2V1	-10486
OR10J3	-10447
OR5AC2	-10429
OR51A7	-10428
OR52L1	-10401
OR10P1	-10392
OR52N2	-10390
OR51D1	-10384
OR2T3	-10382
OR10Z1	-10365
OR4D6	-10360
OR56B4	-10331
OR10A3	-10325
OR10K2	-10320
OR56B1	-10276
OR13C2	-10266
OR2D3	-10231
OR10H4	-10196
OR1G1	-10191
OR9Q2	-10163

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
OR2V1	-10486.0
OR10J3	-10447.0
OR5AC2	-10429.0
OR51A7	-10428.0
OR52L1	-10401.0
OR10P1	-10392.0
OR52N2	-10390.0
OR51D1	-10384.0
OR2T3	-10382.0
OR10Z1	-10365.0
OR4D6	-10360.0
OR56B4	-10331.0
OR10A3	-10325.0
OR10K2	-10320.0
OR56B1	-10276.0
OR13C2	-10266.0
OR2D3	-10231.0
OR10H4	-10196.0
OR1G1	-10191.0
OR9Q2	-10163.0
OR51G2	-10129.0
OR4M1	-10116.0
OR52E4	-10108.0
OR8A1	-10082.0
OR13C8	-10057.0
OR8H3	-10033.0
OR52I1	-10020.0
OR5A1	-10013.0
OR8D2	-9971.0
OR51G1	-9951.0
OR7D4	-9888.0
OR2T12	-9866.0
OR2A5	-9852.0
OR51F1	-9849.0
OR5K1	-9837.0
OR6C65	-9806.0
OR9G1	-9777.5
OR9G9	-9777.5
OR10G8	-9772.0
OR1E1	-9722.0
OR10C1	-9721.0
OR5T1	-9709.0
OR51L1	-9708.0
OR10S1	-9687.0
OR2G2	-9686.0
OR10V1	-9634.0
OR4D11	-9622.0
OR6C6	-9605.0
OR5F1	-9577.0
OR51V1	-9554.0
OR13A1	-9517.0
OR51S1	-9503.0
OR6T1	-9483.0
OR4K5	-9482.0
CNGA4	-9459.0
OR52I2	-9439.0
OR4D10	-9421.0
OR12D3	-9374.0
OR1S1	-9326.0
OR2T8	-9304.0
OR5D16	-9295.0
OR5P3	-9258.0
OR6C2	-9223.0
OR10A7	-9213.0
OR8J3	-9204.0
OR1A1	-9170.0
OR10K1	-9134.0
OR2AK2	-9092.0
OR2H1	-9080.0
OR52A1	-9054.0
OR11H6	-9032.0
OR6S1	-8999.0
OR5V1	-8977.0
OR51E2	-8949.0
OR6C75	-8934.0
OR11A1	-8906.0
CNGB1	-8888.0
OR5M9	-8837.0
OR4E2	-8824.0
OR52N1	-8775.0
OR2W3	-8747.0
OR12D2	-8723.0
OR10G7	-8712.0
RTP2	-8696.0
OR2G6	-8693.0
OR1M1	-8692.0
OR2M5	-8680.0
OR51B2	-8636.0
OR52H1	-8631.0
OR3A3	-8630.0
OR51I1	-8624.0
OR6B1	-8595.0
OR56A3	-8572.0
OR52B2	-8557.0
OR4L1	-8538.0
OR8B12	-8530.0
OR5L2	-8495.0
OR13C4	-8436.0
OR4K15	-8418.0
OR5H15	-8416.0
OR51B5	-8367.0
OR2S2	-8311.0
OR2B2	-8278.0
OR3A1	-8245.0
OR5AS1	-8201.0
OR14C36	-8162.0
OR14J1	-8142.0
OR5T2	-8140.0
OR5A2	-8136.0
OR1C1	-8116.0
OR2B3	-8111.0
OR8K1	-8103.0
OR2L2	-8051.0
OR52M1	-8042.0
OR2A2	-7988.0
OR7A17	-7957.0
OR10H1	-7897.0
OR5K2	-7868.0
OR9A4	-7780.0
OR10J1	-7779.0
OR52K2	-7752.0
OR1A2	-7731.0
OR8B4	-7712.0
OR6K6	-7708.0
OR10G2	-7692.0
OR52J3	-7625.0
OR5AP2	-7623.0
OR6F1	-7602.0
OR2K2	-7594.0
OR56A4	-7568.0
OR52A5	-7513.0
OR2A14	-7476.0
OR14I1	-7470.0
OR10J5	-7450.0
OR51F2	-7447.0
OR9G4	-7409.0
OR8D4	-7375.0
OR51B4	-7339.0
OR51A2	-7222.0
OR2C3	-7209.0
OR5AR1	-7194.0
OR8J1	-7176.0
OR13F1	-7160.0
ADCY3	-7084.0
OR2H2	-7056.0
OR10A4	-7032.0
OR2AP1	-7004.0
OR1E2	-6993.0
OR1B1	-6982.0
OR11H4	-6930.0
OR10H3	-6926.0
OR2M4	-6908.0
OR2T1	-6904.0
OR5M11	-6894.0
OR10A2	-6869.0
OR8B8	-6853.0
OR4N2	-6786.0
OR10X1	-6726.0
OR2B11	-6646.0
OR51Q1	-6632.0
REEP1	-6630.0
OR6K2	-6597.0
OR5T3	-6547.0
OR2AG1	-6461.0
OR5L1	-6386.0
OR1L1	-6362.0
OR4K2	-6242.0
OR2L3	-6182.0
OR6Y1	-6145.0
OR8S1	-6052.0
OR5M1	-5998.0
OR7G2	-5994.0
OR52W1	-5986.0
OR1L6	-5820.0
OR4D9	-5718.0
OR2AT4	-5606.0
OR8K5	-5601.0
OR2M3	-5595.0
OR51I2	-5581.0
OR8U3	-5578.0
OR2C1	-5333.0
OR6C70	-5276.0
OR4N5	-5253.0
OR6C76	-5214.0
OR1S2	-5212.0
OR4D1	-5180.0
OR6X1	-5177.0
OR2D2	-5152.0
OR11G2	-5097.0
OR7D2	-5044.0
OR7C1	-5005.0
OR51T1	-4940.0
OR8G1	-4829.0
RTP1	-4782.0
OR10H2	-4769.0
OR10G9	-4744.0
OR1F1	-4580.0
OR2F2	-4577.0
OR10Q1	-4576.0
OR2M2	-4415.0
ANO2	-4191.0
OR56A1	-4066.0
OR52R1	-4023.0
OR13C9	-3855.0
OR5B2	-3730.0
OR5K4	-3506.0
OR5D14	-3432.0
OR4A15	-3287.0
OR6B2	-3247.0
OR10A5	-3154.5
OR13C3	-3098.0
OR8I2	-3064.0
OR1L4	-2992.0
OR2T27	-2822.0
OR4A47	-2652.0
OR9A2	-2589.0
OR2Y1	-2588.0
OR10AD1	-2506.0
OR4D5	-2487.0
OR1K1	-2449.0
OR6B3	-2353.0
OR4C6	-2258.0
OR2M7	-2254.0
OR1Q1	-1999.0
OR4K1	-1929.0
OR6C1	-1845.0
OR7A5	-1744.0
OR4C16	-1620.0
OR1I1	-1612.0
OR6V1	-1434.0
OR6M1	-1356.0
OR52E8	-1227.0
OR2AG2	-1026.0
OR4K13	-1007.0
OR2F1	-981.0
OR4C15	-888.0
OR6P1	-794.0
OR2L13	-755.0
OR51E1	-738.0
OR5J2	-647.0
GNAL	-592.0
OR6N2	-585.0
OR8G5	-514.0
OR4K14	-492.0
GNB1	-354.0
OR5B21	-218.0
OR5B12	-112.0
OR8K3	-107.0
EBF1	-80.0
OR5W2	192.0
OR6C4	309.0
OR6K3	352.0
OR2V2	485.0
OR9I1	585.0
OR5K3	712.0
OR5I1	1028.0
OR7G1	1190.0
OR2W1	1290.0
OR13J1	1467.0
OR6C68	1514.0
OR1L3	1518.0
OR5D18	1565.0
OR5AN1	1835.0
OR2G3	1866.0
OR11L1	1930.0
OR52B6	2059.0
OR1D2	2109.0
OR4K17	2123.0
OR2T6	2124.0
OR8U8	2143.0
OR5B17	2223.0
OR8U1	2458.0
OR8H1	2541.0
OR52E6	2579.0
OR14A16	2827.0
OR4S1	2910.0
OR2T11	3013.0
OR10G4	3056.0
OR9Q1	3168.0
OR8B2	3503.0
OR5H2	3509.0
OR8D1	3531.0
OR51B6	3731.0
OR2AE1	3765.0
OR6N1	3770.0
OR52K1	3773.0
OR4C45	3798.0
OR52E2	3868.0
OR5H6	3956.0
OR4F6	3998.0
OR2T4	4021.0
OR5B3	4146.0
OR10A6	4175.0
OR6A2	4398.0
OR4F15	5235.0
OR4D2	5678.0
OR7E24	5687.0
OR2T33	5697.0
OR7C2	5950.0
OR2Z1	5974.0
OR4A16	6162.0
OR6C74	6264.0
OR5M3	6335.0
OR10H5	6425.0
OR10AG1	6427.0
OR51M1	6514.0
OR4X2	6592.0
OR4A5	6638.0
OR5M8	6649.0
OR2L5	6902.0
OR4C12	6979.0
OR10G3	7243.0
OR13D1	7341.0
OR5AK2	7357.0
OR4C3	7660.0
OR2A12	7667.0
OR2J2	7799.0
OR1L8	7905.0
OR7G3	8451.0
OR5AU1	8579.0
GNG13	8769.0
OR2B6	8866.0
OR2L8	8897.0
OR52D1	8903.0
LHX2	8981.0
OR1J2	9051.0
OR9K2	9072.0
OR6C3	9100.0
OR4X1	9151.0
OR5P2	9223.0
LDB1	9297.0
OR4B1	9953.0
OR3A2	10127.0
OR13G1	10280.0
OR5M10	10290.0
OR5D13	10310.0
OR10W1	10459.0
OR1J4	10529.0
OR1N1	10569.0
OR7A10	10584.0
OR10T2	10636.0
OR5C1	10747.0
OR4C46	10956.0
OR56A5	11075.0
OR1N2	11138.0
OR5H1	11402.0
OR1J1	11421.0
OR6Q1	11447.0

---

REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

	1161
set	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION
setSize	1336
pANOVA	1.86e-24
s.dist	0.166
p.adjustANOVA	1.02e-21

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ZNF860	11445
TAF7	11408
NDUFA4	11315
RETN	11227
ZNF595	11217
ZNF468	11178
DDIT4	11147
ZNF658	11145
CASP10	11122
ZNF626	11086
ZNF304	11041
ZNF233	10987
ZNF286A	10950
ZNF43	10949
ZNF510	10914
ZNF621	10907
SOCS4	10822
BTG2	10817
H3-3A	10816
ZNF320	10813

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ZNF860	11445.0
TAF7	11408.0
NDUFA4	11315.0
RETN	11227.0
ZNF595	11217.0
ZNF468	11178.0
DDIT4	11147.0
ZNF658	11145.0
CASP10	11122.0
ZNF626	11086.0
ZNF304	11041.0
ZNF233	10987.0
ZNF286A	10950.0
ZNF43	10949.0
ZNF510	10914.0
ZNF621	10907.0
SOCS4	10822.0
BTG2	10817.0
H3-3A	10816.0
ZNF320	10813.0
NFE2	10812.0
SOX2	10785.0
SYMPK	10779.0
NR2F1	10756.0
SP7	10742.0
ZNF761	10659.0
HEY1	10656.0
LEF1	10638.0
CITED4	10631.0
NR4A2	10620.0
ZNF790	10618.0
ZNF552	10607.0
ELOC	10605.0
ZNF710	10598.0
HIPK1	10586.0
ZNF154	10585.0
H2AC4	10558.0
CDC25C	10524.0
NR1H2	10523.0
ZNF641	10513.0
H2BC17	10497.0
RBM8A	10482.0
SLC2A3	10470.0
ZNF701	10462.0
TXN	10424.0
MYBL2	10417.0
RARG	10410.0
POU4F2	10407.0
ELOB	10398.0
ZNF662	10397.0
ZNF2	10355.0
ZNF700	10343.0
EAF2	10333.0
DLX5	10316.0
H4C16	10315.0
H2BC15	10314.0
ZNF564	10311.0
BAX	10307.0
ZNF729	10299.0
ZNF607	10285.0
POMC	10266.0
COX6A1	10262.0
PRKAG1	10252.0
PLK3	10236.0
ZNF155	10230.0
PF4	10175.0
ZNF285	10172.0
ZNF577	10167.0
NFYB	10159.0
NR2E1	10148.0
CNOT8	10145.0
ZNF256	10126.0
RXRG	10109.0
H3-3B	10095.0
FOXG1	10091.0
H4C3	10086.0
LMO2	10082.0
TFAP2A	10053.0
H2AC6	10052.0
RGCC	10050.0
H3C2	10037.0
PSMD13	10036.0
ZNF660	10029.0
ZNF730	10023.0
MIR137	10010.0
CTSL	10003.0
CLP1	10002.0
ZFP28	9998.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
MED6	9947.0
CCN2	9941.0
SNAPC3	9930.0
ZNF92	9921.0
H2AC8	9917.0
ZNF25	9892.0
MAP2K6	9884.0
ZNF135	9880.0
CSTF3	9859.0
FOS	9823.0
ZNF234	9814.0
GAMT	9780.0
CSNK2A1	9778.0
ZNF211	9767.0
HAND2	9757.0
PITX2	9735.0
H3C12	9726.0
TNFRSF10B	9724.0
H2BC21	9693.0
ZNF582	9691.0
TFAP2B	9688.0
ZNF543	9683.0
PRR5	9679.0
ANAPC10	9626.0
ZNF436	9596.0
TACO1	9568.0
TRIM28	9567.0
COX5B	9564.0
ZNF14	9562.0
PIP4P1	9547.0
THOC6	9539.0
RARA	9534.0
SUPT4H1	9529.0
ZNF496	9490.0
BIRC5	9463.0
H2BC8	9455.0
ATXN3	9433.0
POU2F2	9431.0
SOCS3	9415.0
H2AC7	9407.5
H2BC7	9407.5
NR4A3	9398.0
ZNF566	9383.0
PPARD	9380.0
BMP2	9379.0
POLR2C	9358.0
STAT1	9354.0
TFAP2E	9353.0
VENTX	9327.0
TNRC6B	9323.0
SMARCE1	9314.0
SESN3	9305.0
LDB1	9297.0
ZNF668	9287.0
AGRP	9268.0
PRKAA1	9265.0
SPP1	9241.0
UBE2S	9214.0
GLS2	9199.0
ZNF718	9190.0
CCNB1	9175.0
NPY	9152.0
CDKN2B	9139.0
ZNF679	9107.0
LAMTOR4	9078.0
NR2F6	9062.0
PPARGC1B	9056.0
ZNF70	9042.0
H2AZ1	9026.0
H2AC20	9019.0
SPI1	9010.0
MEAF6	9007.0
MED25	9000.0
MED31	8993.0
ZKSCAN7	8991.0
LAMTOR1	8990.0
LSM11	8987.0
CBX5	8962.0
ZNF264	8954.0
UBB	8935.0
KMT5A	8915.0
RBBP5	8902.0
TP53RK	8899.0
E2F5	8896.0
JUN	8891.0
JUNB	8886.0
BTG1	8878.0
ZNF124	8872.0
NKX2-5	8855.0
COX6B1	8837.0
AURKA	8822.0
ZNF136	8810.0
ITGA5	8800.0
ZNF418	8782.0
SMAD7	8777.0
ZNF551	8764.0
TEAD2	8759.0
ACTL6B	8734.0
ZNF557	8731.0
SKIC8	8720.0
ZNF555	8710.0
TGIF1	8699.0
ZNF747	8684.0
ZNF785	8668.0
PLK2	8667.0
MED7	8654.0
GPI	8647.0
TGIF2	8645.0
ZNF439	8622.0
PSMA6	8609.0
ZNF703	8599.0
RRAGA	8589.0
CDC23	8577.0
SLBP	8576.0
REST	8553.0
PCNA	8551.0
ZNF222	8548.0
SMARCD3	8540.0
CTLA4	8505.0
POLR2G	8490.0
CEBPB	8485.0
ELL3	8462.0
TXNIP	8447.0
BCL6	8442.0
GADD45A	8412.0
MED30	8403.0
ING2	8370.0
CTSV	8307.0
RNF2	8302.0
ZNF226	8298.0
BCL2L11	8291.0
BARD1	8265.0
POU2F1	8237.0
ZNF770	8236.0
ZNF625	8209.0
CCNK	8203.0
EPC1	8192.0
ZNF480	8181.0
PSMC6	8173.0
ZNF215	8170.0
MED26	8161.0
SNRPF	8155.0
CCNH	8147.0
MIR24-2	8125.0
BRPF1	8111.0
ZNF775	8099.0
PRDM1	8097.0
MEN1	8092.0
CDC26	8079.0
PCGF5	8078.0
ZNF614	8067.0
ZNF549	8035.0
SCO1	8009.0
SUPT16H	8002.0
TP53	7995.0
ZSCAN32	7982.0
E2F1	7979.0
DLX6	7935.0
NKX3-2	7910.0
IL2RA	7909.0
MIR27A	7889.0
ZNF529	7869.0
PTPN11	7860.0
NR5A2	7819.0
RPA3	7810.0
PSME3	7776.0
IL6	7762.0
CNOT6	7759.0
THOC1	7757.0
ZNF547	7740.0
DYRK2	7726.0
ZNF506	7725.0
CLDN5	7701.0
RPA2	7679.0
PTPN1	7678.0
H3C4	7677.0
NR1H3	7673.0
COX14	7670.0
ZNF18	7658.0
ZNF442	7657.0
HES1	7645.0
ZNF570	7633.0
DAXX	7619.0
ZNF333	7597.0
ZNF253	7590.0
MDM4	7582.0
ZNF225	7521.0
ZNF548	7510.0
GATAD2B	7509.0
DDB2	7500.0
RAD9B	7481.0
ZNF37A	7477.0
ZNF585B	7469.0
CITED2	7465.0
CHD3	7459.0
LSM10	7451.0
SMAD2	7447.0
PPP1R13L	7435.0
ZNF771	7427.0
ZNF33A	7425.0
UBE2E1	7409.0
ZNF540	7404.0
MYB	7392.0
ZNF382	7391.0
MIR24-1	7385.0
RNF34	7366.0
H2BC11	7363.0
H2BC5	7354.0
VEGFA	7320.0
SCO2	7311.0
CPSF7	7303.0
ZNF214	7281.0
GAD2	7277.0
CNOT6L	7270.0
RNU4ATAC	7266.0
DLL1	7194.0
MOV10	7179.0
GTF2A1	7167.0
ALYREF	7137.0
RFC4	7122.0
RXRA	7109.0
MYC	7102.0
RPAP2	7080.0
NOP2	7077.0
TAF5	7067.0
HEY2	7046.0
TBX5	7028.0
NFYA	7024.0
ZNF17	7005.0
CCNT2	6992.0
ARID3A	6976.0
ZNF431	6974.0
PRDX1	6971.0
WRN	6947.0
PERP	6942.0
ELL2	6910.0
H2BC3	6877.0
ZNF180	6873.0
BBC3	6869.0
CDK5R1	6845.0
ARID1A	6834.0
CBFB	6811.0
E2F7	6809.0
CBX4	6802.0
VDR	6798.0
CNOT4	6774.0
TWIST1	6771.0
ZNF514	6768.0
SNAPC4	6760.0
PSMB3	6752.0
CDK7	6742.0
SRSF6	6736.0
CCNG2	6733.0
ZNF528	6728.0
HDAC5	6726.0
ICE1	6723.0
IHH	6713.0
ZNF792	6694.0
CRH	6669.0
ZNF324B	6662.0
PSMD12	6656.0
ZNF569	6651.0
TTC5	6635.0
TNFRSF10D	6631.0
SRSF5	6621.0
GATA4	6611.0
OCLN	6601.0
YWHAQ	6594.0
ZKSCAN4	6593.0
ZNF440	6577.0
ZNF677	6570.0
RBBP8	6518.0
H4C1	6505.0
RYBP	6493.0
CAMK2D	6488.0
TCF7	6429.0
SESN2	6408.0
U2AF1L4	6378.0
BMI1	6356.0
CCNT1	6333.0
SARNP	6326.0
EXO1	6320.0
ZNF764	6299.0
CAMK4	6278.0
SSRP1	6269.0
ELF1	6244.0
COX7C	6211.0
ZKSCAN3	6189.0
CSNK2B	6147.0
ZNF688	6134.0
ANAPC7	6124.0
ZNF667	6113.0
ZNF334	6096.0
PSMB7	6049.0
MSX2	6047.0
KLF4	6041.0
RMI1	6032.0
SNRPG	6029.0
RBBP4	6026.0
ARID2	5986.0
SYT10	5976.0
NPPA	5966.0
XPO1	5947.0
GPAM	5938.0
ESRRA	5898.0
ZNF443	5890.0
CPSF3	5889.0
POLR2I	5881.0
BLM	5877.0
RPRD1A	5872.0
ESR1	5862.0
CBX2	5858.0
ZNF287	5857.0
H4C2	5849.0
HDAC2	5842.0
H2AJ	5832.0
ZFP1	5827.0
H2AX	5821.0
TIGAR	5810.0
MED8	5793.0
KAT5	5792.0
ANAPC2	5784.0
NPAS4	5779.0
PDPK1	5751.0
RFC5	5739.0
CNOT2	5693.0
GATAD2A	5679.0
FYTTD1	5663.0
RNF111	5654.0
RNU12	5640.0
ZNF429	5633.0
H4C12	5591.0
CTR9	5587.0
CAT	5586.0
ZNF875	5578.0
ANAPC11	5571.0
INTS14	5540.0
SOD2	5529.0
ZNF682	5515.0
CDK9	5514.0
ZNF736	5502.0
MED13	5495.0
YWHAH	5488.0
CASP6	5479.0
CDK1	5463.0
COX11	5453.0
PSMC1	5452.0
CBX3	5436.0
PPP2R1A	5421.0
ZNF619	5414.0
FZR1	5395.0
H4C8	5375.0
DEK	5370.0
MAPKAPK5	5347.0
ZNF599	5345.0
KAT6A	5343.0
ZSCAN25	5336.0
KIT	5306.0
NFKB1	5242.0
FOXO1	5225.0
ZNF12	5216.0
ZNF100	5211.0
COX18	5210.0
ZNF692	5196.0
ZNF839	5192.0
PRKCB	5164.0
CASC3	5144.0
ERBB2	5140.0
TAF12	5134.0
IL3	5133.0
ZNF721	5124.0
KMT2E	5120.0
ZNF724	5115.0
PSMD8	5087.0
ZNF471	5073.0
ZNF331	5069.0
GTF2H5	5045.0
SATB2	5015.0
CTSK	5006.0
ATM	4998.0
ZNF79	4971.0
ZNF571	4962.0
CSNK2A2	4931.0
ANAPC16	4927.0
ZNF655	4836.0
ZNF230	4827.0
TAF9	4813.0
SRSF7	4744.0
FKBP5	4731.0
FBXO32	4726.0
GLS	4709.0
ZNF669	4703.0
ZNF26	4690.0
MLLT3	4669.0
CDKN1B	4666.0
NPM1	4661.0
INTS2	4659.0
PPP2R5C	4656.0
ZNF627	4650.0
MED20	4636.0
PSMB10	4635.0
YY1	4593.0
RSPO3	4589.0
TNFRSF10A	4563.0
ZNF561	4560.0
CALM1	4537.0
SMYD2	4532.0
NELFB	4523.0
BID	4499.0
THOC3	4495.0
ZNF343	4484.0
CCND3	4481.0
TAF15	4480.0
SMARCD1	4478.0
ZNF235	4463.0
PRMT5	4449.0
PSMD3	4433.0
CDC27	4430.0
ZKSCAN1	4429.0
UBE2C	4394.0
ZNF565	4385.0
CDKN1A	4380.0
ITGA4	4351.0
TCEA1	4339.0
APAF1	4331.0
AURKB	4328.0
ZNF470	4308.0
H3C6	4303.0
AGO1	4301.0
RAD51D	4279.0
PRMT1	4277.0
TNRC6A	4276.0
GTF2E2	4262.0
GPS2	4260.0
TRIM63	4241.0
ICE2	4237.0
ARNT	4232.0
CNOT3	4227.0
UBE2D3	4215.0
SMARCA2	4199.0
PSMA3	4156.0
ZNF680	4151.0
FANCD2	4136.0
ZNF746	4132.0
KCTD15	4122.0
CUL1	4104.0
ZNF774	4093.0
ZNF726	4087.0
GSK3B	4062.0
ZNF398	4052.0
ZNF773	4050.0
TCF12	4030.0
COX6C	4023.0
H2AZ2	4022.0
RHNO1	4015.0
RUNX2	4006.0
ZNF613	4005.0
ZNF776	4000.0
PCGF6	3985.0
TXNRD1	3982.0
ZNF175	3980.0
NCBP1	3972.0
ZNF212	3970.0
ZNF562	3969.0
ZNF143	3961.0
ZNF684	3943.0
ZNF519	3938.0
INTS13	3937.0
ZNF385A	3879.0
ZNF586	3874.0
TAF4B	3873.0
BDNF	3865.0
SUPT6H	3854.0
BMAL1	3841.0
PSMC2	3840.0
TFAP2C	3823.0
PINK1	3814.0
ZNF492	3787.0
NR1D2	3761.0
PRELID3A	3753.0
RAD17	3742.0
RRM2B	3735.0
MIR132	3733.0
INTS5	3729.0
TPX2	3724.0
ZNF350	3700.0
ESR2	3686.0
SERPINE1	3685.0
ATR	3678.0
YWHAZ	3670.0
TAF6	3656.0
PVALB	3652.0
POU4F1	3636.0
RFFL	3618.0
ZNF282	3605.0
ZNF786	3575.0
TRPC3	3572.0
SRC	3558.0
MGA	3547.0
USP7	3536.0
GRIA2	3534.0
SESN1	3504.0
RABGGTA	3502.0
INTS3	3463.0
TP53INP1	3460.0
PPARA	3456.0
PLAGL1	3452.0
RBL2	3425.0
POLR2K	3416.0
ZNF99	3411.0
PIP4K2C	3408.0
ZNF473	3407.0
ING5	3400.0
JAG1	3381.0
ESRRG	3371.0
PMAIP1	3313.0
CNOT9	3310.0
ZFPM1	3309.0
NCOR2	3299.0
ZNF189	3294.0
ZNF461	3280.0
DDIT3	3275.0
ZNF727	3253.0
ZNF426	3245.0
CNOT11	3226.0
ZNF671	3218.0
PAF1	3202.0
YWHAG	3187.0
MSH2	3165.0
SMURF1	3156.0
ZNF267	3145.0
SGK1	3134.0
PRDX5	3124.0
RUNX1	3122.0
CDK13	3106.0
NDRG1	3105.0
PSMC5	3099.0
HDAC1	3086.0
ZNF337	3065.0
ZNF420	3063.0
MAF	3053.0
MTA2	3044.0
SRSF3	3016.0
COX5A	3007.0
ZNF560	2996.0
CDK2	2988.0
PRKAB1	2975.0
TP73	2972.0
PABPN1	2964.0
UBA52	2963.0
PSMB1	2960.0
RNU11	2930.0
ZNF606	2928.0
INTS4	2880.0
CPSF6	2857.0
ANAPC4	2830.0
LAMTOR5	2820.0
HDAC10	2816.0
TNFRSF10C	2813.0
ZNF213	2809.0
DNA2	2805.0
IGFBP3	2803.0
POLR2B	2795.0
SKP2	2789.0
ZNF254	2778.0
SOX9	2770.0
ARID1B	2763.0
HDAC7	2761.0
ZNF71	2746.0
CRADD	2719.0
BCL2L14	2717.0
ZKSCAN8	2704.0
ZNF589	2697.0
MED24	2682.0
ZNF263	2673.0
ZNF197	2668.0
ZNF777	2666.0
H2BC1	2654.0
LBR	2649.0
THRA	2630.0
ZNF583	2624.0
TGFA	2620.0
PHC1	2610.0
ABL1	2597.0
PSMB2	2596.0
CHEK1	2585.0
CREBBP	2578.0
SMAD1	2562.0
H3C10	2553.0
SCMH1	2508.0
PSMA1	2497.0
ZNF268	2496.0
PRKAB2	2481.0
SIN3A	2466.0
PSMB5	2455.0
PSMD2	2443.0
CYCS	2424.0
PSMA7	2417.0
RAD51	2407.0
ZNF709	2404.0
NFATC2	2401.0
RBM14	2399.0
ZNF248	2397.0
PTEN	2393.0
AKT1	2390.0
SNW1	2377.0
KMT2A	2369.0
ZNF221	2364.0
MAPKAP1	2338.0
ZNF804B	2337.0
NELFCD	2322.0
CCND1	2318.0
ZNF19	2291.0
PSMB4	2281.0
RNMT	2264.0
RORB	2262.0
ZNF665	2261.0
ZNF441	2237.0
RAD1	2227.0
INTS10	2173.0
YAP1	2136.0
ZNF112	2092.0
THBS1	2088.0
ZC3H11A	2076.0
WDR33	2071.0
HSPD1	2064.0
ZNF347	2050.0
PSMD4	2042.0
H2BC10	2021.0
SURF1	2019.0
CDC40	1999.0
NR1I2	1961.0
TBL1XR1	1940.0
EIF4A3	1929.0
HDAC11	1927.0
RPTOR	1894.0
RPA1	1885.0
SMURF2	1884.0
ZNF749	1881.0
ZNF446	1871.0
ZNF750	1865.0
PPP2CA	1855.0
ZNF432	1840.0
NRBP1	1838.0
ZFP30	1819.0
ZNF791	1814.0
JMY	1804.0
MAML2	1794.0
ZNF782	1778.0
ZNF28	1772.0
CSTF2T	1767.0
RFC2	1760.0
PPARG	1757.0
SETD1A	1753.0
GTF2H3	1736.0
WWP1	1718.0
NABP2	1706.0
GATA2	1695.0
CSTF1	1690.0
ZNF141	1683.0
ZNF611	1666.0
ZNF500	1665.0
NELFE	1662.0
ATRIP	1661.0
ZNF706	1657.0
PPARGC1A	1629.0
CAV1	1619.0
PIP4K2A	1613.0
MNAT1	1602.0
ELL	1591.0
ZNF224	1579.0
PSME1	1571.0
LAMTOR2	1570.0
GPX2	1567.0
YAF2	1562.0
TOPBP1	1558.0
INTS6	1553.0
CASP2	1545.0
SKP1	1543.0
ZNF714	1508.0
ZNF544	1507.0
POLR2A	1481.0
ZIM2	1477.0
KRAS	1468.0
INTS12	1462.0
ZNF419	1457.0
BRD2	1431.0
LEO1	1429.0
HDAC4	1418.0
HTT	1406.0
AFF4	1392.0
ZNF460	1387.0
IWS1	1375.0
HIVEP3	1358.0
PPP1R13B	1347.0
ZNF20	1336.0
RB1	1335.0
RMI2	1319.0
SSU72	1316.0
SFN	1261.0
PSME2	1245.0
CGB5	1225.0
PSMA2	1218.0
PSMB6	1163.0
CBX8	1158.0
SMAD3	1155.0
CHD4	1146.0
E2F6	1123.0
ZNF615	1101.0
AXIN1	1098.0
ZNF697	1086.0
GTF2B	1075.0
SNAPC5	1071.0
NBN	1064.0
SP1	1043.0
ZNF202	1009.0
MED4	996.0
SNRPE	966.0
ZNF257	959.0
EHMT1	955.0
SIRT3	952.0
NRBF2	912.0
MAPK3	901.0
GAD1	848.0
RFC3	822.0
CDK8	816.0
KAT2B	811.0
ZNF433	809.0
ZNF227	786.0
ZNF546	778.0
EP300	777.0
ZFP69B	761.0
CCNA1	745.0
H3C1	733.0
PML	732.0
H4C11	725.0
TP53I3	714.0
ZNF169	697.0
ZNF681	696.0
TAF3	666.0
H4C5	654.0
MED17	628.0
MDM2	617.0
RXRB	586.0
USP2	577.0
RELA	572.0
ZNF383	569.0
UBE2D1	557.0
ZNF568	547.0
CDC16	525.0
H2BC12	519.0
MED1	506.0
OPRK1	498.0
RRAGC	489.0
CNOT10	478.0
ZNF696	467.0
PHF20	457.0
POLR2E	455.0
NCBP2	442.0
H3C11	416.0
COL1A1	412.0
NR3C1	406.0
PRMT6	389.0
PPM1A	361.0
RPRD2	346.0
POLR2H	334.0
SEM1	329.0
BLK	314.0
TAF10	308.0
EZH2	243.0
ATF2	234.0
YBX1	223.0
SMAD4	194.0
ZNF10	171.0
H4C4	162.0
TP53BP2	150.0
ZFP2	148.0
ZNF563	134.0
ZFP69	129.0
AIFM2	96.0
MRE11	94.0
ZNF517	55.0
MAML3	30.0
CCND2	11.0
PLXNA4	-15.0
SETD9	-45.0
PSMB8	-53.0
RBPJ	-55.0
INTS8	-68.0
COX8A	-109.0
GEM	-115.0
ZFP90	-150.0
PCF11	-153.0
STUB1	-163.0
E2F8	-176.0
NABP1	-177.0
PTPN4	-226.0
BRCA1	-237.0
EAF1	-273.0
CREB1	-314.0
ELOA2	-319.0
UBC	-323.0
H3C8	-350.0
PPP2R1B	-352.0
LGALS3	-374.0
CAMK2G	-405.0
COX20	-406.0
PSMD5	-411.0
DPY30	-441.0
FOXO3	-442.0
PGR	-473.0
GTF2H4	-482.0
CDK6	-504.0
AKT3	-509.0
BANP	-519.0
PSMA5	-534.0
ANAPC1	-538.0
SNAPC1	-542.0
POLR2F	-559.0
KRBA1	-561.0
ZNF708	-588.0
RABGGTB	-609.0
MAX	-612.0
SRSF2	-624.0
ZNF23	-648.0
SETD1B	-663.0
MAPK14	-685.0
RING1	-719.0
PSMB9	-734.0
TOP3A	-739.0
INTS7	-770.0
PSME4	-771.0
PAPOLA	-775.0
RRAGD	-797.0
PSMD11	-805.0
ZNF490	-825.0
PARP1	-847.0
ZNF584	-851.0
TAF2	-880.0
RNGTT	-921.0
POLDIP3	-926.0
PHC3	-931.0
MED15	-948.0
TEAD4	-949.0
COX16	-1036.0
AGO4	-1047.0
HUS1	-1084.0
ZNF616	-1101.0
RHEB	-1111.0
GLI3	-1117.0
SRSF1	-1120.0
SKI	-1125.0
FURIN	-1134.0
ZNF486	-1174.0
CHTOP	-1176.0
RBFOX1	-1197.0
TNRC6C	-1236.0
CDKN2A	-1239.0
MDC1	-1241.0
OPRM1	-1262.0
DHX38	-1284.0
FANCC	-1290.0
EED	-1311.0
ERCC2	-1393.0
TGFB1	-1410.0
COL1A2	-1423.0
CSF2	-1429.0
ZNF266	-1437.0
ZNF454	-1492.0
TBP	-1504.0
ZNF664	-1514.0
GTF2F1	-1517.0
DDX39A	-1535.0
ACTL6A	-1547.0
MAML1	-1556.0
PRKCQ	-1576.0
ZNF302	-1577.0
HDAC3	-1583.0
NOC2L	-1589.0
TJP1	-1608.0
ZNF33B	-1623.0
NR2C2AP	-1634.0
TCF7L2	-1635.0
PCGF2	-1658.0
SUPT5H	-1673.0
KMT2C	-1702.0
ZNF596	-1747.0
PPM1D	-1763.0
ERCC3	-1766.0
CR1	-1768.0
MAPK1	-1794.0
ZNF479	-1826.0
GTF2E1	-1829.0
PHAX	-1830.0
HIPK2	-1861.0
CDK4	-1880.0
LRPPRC	-1887.0
ZNF3	-1909.0
CDK5	-1923.0
PSMD7	-1937.0
BRIP1	-1946.0
CPSF1	-1964.0
TFAP2D	-1970.0
CPSF4	-1983.0
KCTD1	-1991.0
RBL1	-2049.0
POLR2D	-2050.0
MEF2C	-2065.0
SRRM1	-2077.0
NFYC	-2086.0
ZNF77	-2088.0
DGCR8	-2101.0
CTDP1	-2116.0
CDC73	-2117.0
FBXW7	-2124.0
TFDP1	-2145.0
ZNF649	-2147.0
PIP4K2B	-2159.0
ZNF311	-2172.0
KDM5B	-2177.0
GATA3	-2179.0
ZKSCAN5	-2189.0
BRPF3	-2206.0
ZNF317	-2224.0
KCTD6	-2265.0
SNRPD3	-2277.0
TAL1	-2319.0
ZNF670	-2336.0
TAF8	-2350.0
ZNF101	-2370.0
SRSF11	-2372.0
ASH2L	-2432.0
ZNF140	-2437.0
AGO3	-2452.0
YWHAB	-2453.0
SNRPB	-2463.0
CCNC	-2482.0
ZNF324	-2527.0
ZNF772	-2533.0
TFDP2	-2551.0
ZNF567	-2558.0
ZNF778	-2572.0
COX19	-2574.0
RICTOR	-2579.0
ZNF74	-2587.0
ZNF485	-2608.0
CCNE2	-2648.0
TP63	-2651.0
RORA	-2672.0
ZNF394	-2714.0
INTS9	-2724.0
ZNF676	-2757.0
CPSF2	-2759.0
ZNF597	-2798.0
NR1D1	-2835.0
ZNF521	-2860.0
YEATS4	-2863.0
TRIM33	-2887.0
ZNF200	-2888.0
PSMD9	-2906.0
HDAC9	-2916.0
TRIAP1	-2946.0
ZNF160	-2962.0
MLH1	-2991.0
RPRD1B	-3011.0
ZIK1	-3018.0
SUMO1	-3031.0
NR3C2	-3037.0
ITCH	-3047.0
ZNF610	-3062.0
RET	-3087.0
ZNF415	-3152.0
ZNF417	-3159.0
ZNF689	-3171.0
PRKAG2	-3173.0
NR2C2	-3177.0
SREBF1	-3191.0
PMS2	-3201.0
TSC2	-3226.0
GRIN2A	-3246.0
SRF	-3253.0
PRKACA	-3280.0
RAD9A	-3359.0
PIDD1	-3362.0
CSF1R	-3370.0
WWOX	-3408.0
POLR2L	-3453.0
NR5A1	-3458.0
TMEM219	-3478.0
ANAPC5	-3528.0
ANAPC15	-3556.0
GTF2A2	-3567.0
MED23	-3601.0
ZNF223	-3631.0
MAPK11	-3633.0
BNIP3L	-3635.0
NAMPT	-3676.0
DDX39B	-3686.0
GPRIN1	-3693.0
GTF2H1	-3725.0
NELFA	-3739.0
ZNF707	-3802.0
H4C6	-3817.0
SMAD6	-3838.0
NCOR1	-3868.0
EHMT2	-3897.0
WDR5	-3915.0
MAGOHB	-3930.0
ZNF114	-3935.0
RBFOX3	-3952.0
GP1BA	-3953.0
NOTCH2	-3966.0
ELOA	-3967.0
KMT2B	-3968.0
AUTS2	-3975.0
ITGBL1	-3978.0
SRSF4	-4008.0
ATAD2	-4011.0
L3MBTL2	-4017.0
MMP13	-4021.0
FAS	-4051.0
PBRM1	-4136.0
SIRT1	-4139.0
ZNF184	-4149.0
PRDM7	-4192.0
ZNF793	-4201.0
ELF2	-4260.0
ZNF138	-4278.0
PCBP4	-4281.0
PHC2	-4284.0
TNKS1BP1	-4286.0
ZNF585A	-4303.0
PIN1	-4308.0
MET	-4322.0
TEAD1	-4350.0
ZNF354A	-4354.0
TSC1	-4355.0
CCNA2	-4363.0
ZNF416	-4371.0
TAF13	-4372.0
MBD3	-4382.0
NOTCH3	-4389.0
PRELID1	-4393.0
SMARCA4	-4396.0
ZNF587	-4427.0
APOE	-4456.0
KAT2A	-4470.0
SLC38A9	-4478.0
WWTR1	-4483.0
COX7A2L	-4486.0
PSMC3	-4492.0
H3C3	-4506.0
NUDT21	-4522.0
NR4A1	-4535.0
FASLG	-4561.0
ZNF274	-4598.0
CAMK2B	-4609.0
GSR	-4610.0
RNPS1	-4620.0
PPP2CB	-4627.0
TCF3	-4646.0
YWHAE	-4657.0
FIP1L1	-4704.0
ZNF250	-4722.0
MED10	-4756.0
RUNX3	-4775.0
SMARCC1	-4778.0
ZFHX3	-4787.0
NR2C1	-4800.0
CDK12	-4819.0
RRM2	-4822.0
ZNF195	-4828.0
H2BC26	-4831.0
ZNF704	-4844.0
GTF2F2	-4849.0
RORC	-4870.0
IQSEC3	-4875.0
ZNF573	-4888.0
SUZ12	-4896.0
LIFR	-4997.0
MAGOH	-5021.0
RAD50	-5022.0
KMT2D	-5043.0
INTS1	-5067.0
CBX6	-5151.0
ZNF605	-5157.0
NOTCH1	-5181.0
ZNF678	-5188.0
SMARCD2	-5201.0
MLLT1	-5205.0
LMO1	-5207.0
PAX5	-5231.0
KRBOX5	-5269.0
RARB	-5295.0
PSMD14	-5297.0
CTNNB1	-5304.0
FANCI	-5307.0
ZNF425	-5323.0
SMARCB1	-5336.0
THOC5	-5341.0
EGFR	-5365.0
SRSF9	-5382.0
SIN3B	-5393.0
H2AC18	-5415.5
H2AC19	-5415.5
TNFRSF18	-5466.0
CARM1	-5492.0
PSMD1	-5508.0
HNF4G	-5515.0
YES1	-5604.0
PSMD6	-5633.0
CDC7	-5634.0
PSMF1	-5638.0
ZNF559	-5699.0
UCMA	-5787.0
MTOR	-5798.0
ZNF445	-5825.0
CNOT1	-5830.0
TCF7L1	-5842.0
ZNF300	-5914.0
TEAD3	-5924.0
ITGAL	-5932.0
CHEK2	-5952.0
TAF11	-6014.0
TAF1L	-6023.0
U2AF2	-6030.0
ZNF75A	-6060.0
THOC7	-6081.0
H4C13	-6090.0
CCNG1	-6092.0
MED16	-6094.0
IGFBP1	-6107.0
ZNF273	-6128.0
SMARCC2	-6163.0
ITGA2B	-6213.0
IL2	-6245.0
FOXO6	-6297.0
GRIN2B	-6363.0
CENPJ	-6375.0
ZNF133	-6381.0
ZNF624	-6435.0
ZNF675	-6459.0
AKT2	-6463.0
NEDD4L	-6474.0
RPS27A	-6484.0
CGB8	-6496.0
MED27	-6534.0
ABCA6	-6535.0
COX4I1	-6540.0
ZNF484	-6545.0
ZNF550	-6567.0
CNOT7	-6586.0
PSMA8	-6587.0
ZNF208	-6633.0
PSMC4	-6643.0
SLU7	-6648.0
PRKAA2	-6662.0
ZNF493	-6665.0
ZNF620	-6677.0
ZNF205	-6698.0
MLST8	-6702.0
BRD1	-6710.0
NOTCH4	-6718.0
ZNF716	-6727.0
TAF4	-6750.0
ESRRB	-6757.0
NLRC4	-6854.0
ZNF45	-6858.0
RBX1	-6897.0
ZNF354C	-6934.0
MOBP	-7028.0
NUAK1	-7030.0
LAMTOR3	-7041.0
ZNF740	-7044.0
ZNF699	-7110.0
INS	-7133.0
AGO2	-7172.0
ZIM3	-7195.0
H2BC14	-7223.0
PSMA4	-7243.0
ZNF430	-7247.0
ZNF691	-7267.0
SKIL	-7356.0
NR6A1	-7500.0
PRDX2	-7552.0
H2BC13	-7559.0
E2F4	-7591.0
UBE2I	-7598.0
BRD7	-7614.0
ZFP37	-7677.0
GCK	-7733.0
SNAPC2	-7790.0
ZC3H8	-7810.0
ZNF556	-7844.0
CCNE1	-7855.0
ZNF30	-7872.0
ZNF554	-7922.0
H2AC14	-7938.0
NR2E3	-7967.0
ZNF735	-7998.0
H4C9	-8005.0
MYL9	-8068.0
STK11	-8147.0
THRB	-8154.0
ZNF530	-8157.0
ZNF483	-8189.0
ARNT2	-8202.0
RTF1	-8219.0
NR0B2	-8269.0
TWIST2	-8359.0
SERPINB13	-8397.0
ZNF34	-8455.0
IFNG	-8460.0
KCNIP3	-8504.0
ZNF354B	-8527.0
SST	-8533.0
G6PC1	-8574.0
CASP1	-8599.0
ZNF600	-8626.0
ZNF738	-8722.0
ZNF799	-8806.0
ZFP14	-8921.0
HNF4A	-8938.0
PCK1	-8954.0
SRRT	-9083.0
NR1H4	-9094.0
INTS11	-9151.0
PRKAG3	-9191.0
ZNF713	-9234.0
ZNF558	-9255.0
NR1I3	-9398.0
STEAP3	-9426.0
MSTN	-9544.0
L3MBTL1	-9606.0
ZNF732	-9614.0
CGA	-9627.0
GLI2	-9651.0
PSMB11	-9711.0
ZNF717	-9761.0
TP53AIP1	-9798.0
CAMK2A	-9993.0
BGLAP	-10015.0
ZNF737	-10098.0
POLR2J	-10431.0

---

REACTOME_CELLULAR_RESPONSES_TO_STIMULI

REACTOME_CELLULAR_RESPONSES_TO_STIMULI

	1314
set	REACTOME_CELLULAR_RESPONSES_TO_STIMULI
setSize	779
pANOVA	1.87e-16
s.dist	0.173
p.adjustANOVA	7.69e-14

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NDUFA4	11315
XBP1	11272
CASTOR1	11199
MT1G	11173
MT1H	11126
HSBP1	11057
SYVN1	10855
H3-3A	10816
GPX1	10815
MT2A	10811
CDKN2D	10796
HMOX2	10643
ELOC	10605
PPP2R5B	10604
H2AC4	10558
ETS2	10521
H2BC17	10497
ID1	10480
RPL26	10476
H1-3	10469

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
NDUFA4	11315.0
XBP1	11272.0
CASTOR1	11199.0
MT1G	11173.0
MT1H	11126.0
HSBP1	11057.0
SYVN1	10855.0
H3-3A	10816.0
GPX1	10815.0
MT2A	10811.0
CDKN2D	10796.0
HMOX2	10643.0
ELOC	10605.0
PPP2R5B	10604.0
H2AC4	10558.0
ETS2	10521.0
H2BC17	10497.0
ID1	10480.0
RPL26	10476.0
H1-3	10469.0
TXN	10424.0
PRDX6	10414.0
ELOB	10398.0
TUBB4B	10395.0
H4C16	10315.0
H2BC15	10314.0
RPL10A	10291.0
MAFG	10281.0
COX6A1	10262.0
ATP6V1G1	10196.0
RPS16	10188.0
ATP6V0E2	10185.0
PREB	10184.0
NFYB	10159.0
SNCB	10155.0
ATP6V0E1	10135.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
PSMD13	10036.0
CREB3	10031.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
USP46	9933.0
H2AC8	9917.0
FNIP1	9896.0
MAP2K6	9884.0
FOS	9823.0
RPL39L	9799.0
RPL36AL	9794.5
CSNK2A1	9778.0
CA9	9764.0
RPL29	9738.0
H3C12	9726.0
LY96	9708.0
H2BC21	9693.0
HSP90B1	9674.0
ANAPC10	9626.0
HSPA8	9600.0
BLVRB	9593.0
TACO1	9568.0
COX5B	9564.0
HSPA2	9522.0
ATF4	9520.0
DCP2	9485.0
POM121	9464.0
H2BC8	9455.0
EXOSC5	9427.0
H2AC7	9407.5
H2BC7	9407.5
DIS3	9332.0
VENTX	9327.0
TNRC6B	9323.0
TUBB6	9322.0
HSPA14	9293.0
BAG5	9232.0
UBE2S	9214.0
P4HB	9206.0
RPS6KA1	9141.0
CDKN2B	9139.0
FKBP14	9132.0
MT1E	9098.0
LAMTOR4	9078.0
CALR	9075.0
CDKN2C	9068.0
H2AZ1	9026.0
H2AC20	9019.0
CRTC3	9011.0
LAMTOR1	8990.0
CREB3L3	8984.0
EIF2AK3	8960.0
CREB3L4	8956.0
UBB	8935.0
JUN	8891.0
RPL27	8846.0
COX6B1	8837.0
RPS28	8785.0
KDM6B	8750.0
SHC1	8740.0
CCL2	8716.0
HSPA5	8652.0
MT3	8629.0
NPLOC4	8621.0
PSMA6	8609.0
ERF	8606.0
H1-0	8604.0
RRAGA	8589.0
CDC23	8577.0
IDH1	8546.0
SERP1	8541.0
SMARCD3	8540.0
DCTN6	8494.0
HIF1A	8488.0
CEBPB	8485.0
TUBA4B	8469.0
TXNIP	8447.0
RPL37A	8438.0
HSPA1B	8434.0
RPL26L1	8414.0
DYNC1LI2	8336.0
RNF2	8302.0
EXTL2	8211.0
RPS19	8176.0
PSMC6	8173.0
DNAJA2	8169.0
GPX7	8130.0
MIR24-2	8125.0
CDC26	8079.0
RAE1	8059.0
NUP58	8047.0
TUBA8	8019.0
SCO1	8009.0
TP53	7995.0
E2F1	7979.0
RPL15	7977.0
NUP43	7960.0
RPL6	7932.0
DNAJB9	7922.0
MT1X	7842.0
HELZ2	7812.0
RPA3	7810.0
NUP35	7791.0
RPL34	7790.0
PSME3	7776.0
TALDO1	7763.0
IL6	7762.0
NUP50	7744.0
RPA2	7679.0
H3C4	7677.0
COX14	7670.0
RPS3A	7611.0
HSPA1A	7602.0
MDM4	7582.0
RPS27L	7580.0
NCF2	7558.0
SQSTM1	7536.0
TXN2	7523.0
ATP6V1F	7506.0
PALB2	7482.0
TUBB4A	7468.0
CITED2	7465.0
UBE2E1	7409.0
HBA1	7395.0
MIR24-1	7385.0
TUBA4A	7384.0
RPL23	7379.0
H2BC11	7363.0
H2BC5	7354.0
RPL35A	7327.0
UBXN7	7323.0
VEGFA	7320.0
SCO2	7311.0
ATP6V1A	7240.0
GCLM	7201.0
GOSR2	7192.0
RPL28	7186.0
KDELR3	7180.0
MOV10	7179.0
HSPA4L	7173.0
DCTN1	7164.0
NOX4	7140.0
RXRA	7109.0
MYC	7102.0
MYDGF	7099.0
ERN1	7086.0
RPL11	7034.0
UFD1	7030.0
NFYA	7024.0
YIF1A	7021.0
MAPKAPK2	7010.0
PRDX1	6971.0
TXNRD2	6962.0
DYNLL2	6886.0
H2BC3	6877.0
TUBB3	6871.0
HSP90AB1	6865.0
CBX4	6802.0
RPS15A	6793.0
GPX8	6765.0
PSMB3	6752.0
FKBP4	6681.0
TNIK	6663.0
PSMD12	6656.0
CHD9	6648.0
ATP6V1G3	6646.0
RPL41	6591.0
RPLP1	6550.0
NUP88	6529.0
H4C1	6505.0
GCLC	6503.0
FAU	6502.0
CAMK2D	6488.0
DYNC1LI1	6419.0
SESN2	6408.0
GML	6396.0
RPL24	6382.0
AJUBA	6380.0
PPP1R15A	6372.0
HSPA13	6357.0
BMI1	6356.0
GSK3A	6340.0
NQO1	6289.0
RPS5	6275.0
COX7C	6211.0
CSNK2B	6147.0
STAT3	6128.0
ANAPC7	6124.0
MT1A	6092.0
PSMB7	6049.0
BAG4	6043.0
NUP155	6039.0
RBBP4	6026.0
NUDT2	5981.0
XPO1	5947.0
EEF1A1	5887.0
STIP1	5861.0
CBX2	5858.0
H4C2	5849.0
H2AJ	5832.0
H2AX	5821.0
KAT5	5792.0
ANAPC2	5784.0
RPL7	5777.0
AQP8	5764.0
PGD	5754.0
SEC31A	5730.0
EXOSC8	5657.0
MEF2D	5652.0
CEBPG	5595.0
H4C12	5591.0
CAT	5586.0
ANAPC11	5571.0
SOD2	5529.0
RPS29	5507.0
ACADVL	5503.0
HSPB1	5499.0
EXOSC1	5477.0
MAP4K4	5456.0
COX11	5453.0
PSMC1	5452.0
RPL36	5403.0
FZR1	5395.0
ACTR10	5394.0
H4C8	5375.0
FNIP2	5354.0
MAPKAPK5	5347.0
TUBB2A	5342.0
DEDD2	5339.0
RPS11	5323.0
TUBA3C	5315.0
ST13	5271.0
NFKB1	5242.0
COX18	5210.0
EGLN3	5150.0
CUL3	5141.0
HMOX1	5129.0
CUL2	5114.0
PSMD8	5087.0
SRXN1	5068.0
POT1	5008.0
ATM	4998.0
RPS20	4993.0
RPS10	4983.0
EXOSC7	4975.0
CSNK2A2	4931.0
ANAPC16	4927.0
RPS9	4917.0
CHAC1	4866.0
RPL37	4854.0
RPL27A	4853.0
EXTL1	4847.0
APOA1	4789.0
DNAJC7	4774.0
MAP1LC3B	4764.0
GFPT1	4742.0
FKBP5	4731.0
ADD1	4725.0
EXOSC4	4711.0
CDKN1B	4666.0
PSMB10	4635.0
LIMD1	4626.0
NLRP3	4550.0
BTRC	4547.0
MAPK9	4542.0
MAFK	4524.0
CREB3L1	4506.0
UBE2D2	4497.0
AKT1S1	4491.0
EGLN2	4466.0
PSMD3	4433.0
CDC27	4430.0
UBE2C	4394.0
CDKN1A	4380.0
DNAJB11	4371.0
RPL18	4341.0
DYNC1H1	4333.0
DYNC1I1	4315.0
RPS23	4307.0
H3C6	4303.0
AGO1	4301.0
IFNB1	4295.0
TNRC6A	4276.0
KPTN	4257.0
ARNT	4232.0
UBE2D3	4215.0
RPL9	4204.0
EDEM1	4186.0
PSMA3	4156.0
CUL1	4104.0
GSK3B	4062.0
ATF5	4051.0
SLC46A1	4031.0
COX6C	4023.0
H2AZ2	4022.0
TXNRD1	3982.0
GPX3	3959.0
RPS21	3934.0
TKT	3916.0
BMAL1	3841.0
PSMC2	3840.0
MTF1	3817.0
MAPK8	3772.0
RPS19BP1	3758.0
ASNS	3747.0
ATR	3678.0
DYNC1I2	3671.0
ATP6V1B2	3629.0
NUP133	3627.0
RPS12	3607.0
NUP160	3568.0
ACD	3521.5
SESN1	3504.0
RPL17	3492.0
VCP	3474.0
PPARA	3456.0
ATP6V1C1	3422.0
MUL1	3367.0
DNAJC3	3357.0
BACH1	3350.0
NCOR2	3299.0
NUP214	3289.0
KEAP1	3287.0
DDIT3	3275.0
ATP6V0D2	3246.0
H1-5	3242.0
UBN1	3233.0
ATOX1	3162.0
DCTN2	3142.0
HYOU1	3132.0
PRDX5	3124.0
PSMC5	3099.0
SOD1	3049.0
CREB3L2	3037.0
COX5A	3007.0
NUP188	2995.0
CDK2	2988.0
SSR1	2973.0
KHSRP	2966.0
UBA52	2963.0
PSMB1	2960.0
RPL13	2937.0
GPX5	2936.0
HDGF	2896.0
NRIP1	2854.0
ANAPC4	2830.0
LAMTOR5	2820.0
RPSA	2801.0
ATP6V0C	2799.0
SKP2	2789.0
CTDSP2	2759.0
DNAJC2	2675.0
EPO	2667.0
PARN	2660.0
H2BC1	2654.0
PHC1	2610.0
PSMB2	2596.0
CREBBP	2578.0
H3C10	2553.0
EGLN1	2550.0
PDIA5	2516.0
SCMH1	2508.0
PSMA1	2497.0
TLN1	2467.0
SIN3A	2466.0
HSPA1L	2463.0
PSMB5	2455.0
PSMD2	2443.0
CYCS	2424.0
PSMA7	2417.0
AKT1	2390.0
DYNLL1	2349.0
TERF2IP	2334.0
SEH1L	2309.0
PSMB4	2281.0
ITFG2	2259.0
MAPKAPK3	2205.0
CYBA	2203.0
ERO1A	2153.0
EXOSC6	2061.0
PSMD4	2042.0
HMGA2	2040.0
H2BC10	2021.0
SURF1	2019.0
H1-1	2008.0
BLVRA	2002.0
CREBRF	1942.0
TBL1XR1	1940.0
RPL38	1935.0
RPL19	1906.0
RPTOR	1894.0
RPA1	1885.0
CRTC2	1843.0
E2F3	1797.0
DCTN5	1751.0
CXCL8	1749.0
BAG1	1747.0
RAI1	1681.0
PPARGC1A	1629.0
KICS2	1589.0
PSME1	1571.0
LAMTOR2	1570.0
GPX2	1567.0
SKP1	1543.0
MAPK7	1493.0
NUP107	1453.0
MT1F	1389.0
RB1	1335.0
RPS7	1305.0
WTIP	1302.0
HIKESHI	1299.0
ABCC1	1293.0
RPS2	1277.0
NFE2L2	1267.0
PSME2	1245.0
MIOS	1243.0
PSMA2	1218.0
STAP2	1205.0
PSMB6	1163.0
BAG2	1161.0
CBX8	1158.0
POM121C	1147.0
NUP62	1081.0
NBN	1064.0
ATP6V1G2	1052.0
SP1	1043.0
TUBB1	1042.0
ETS1	1038.0
HBB	1036.0
TERF1	989.0
ATP6V1D	988.0
NUP85	973.0
TUBAL3	971.0
EHMT1	955.0
RPS14	948.0
DNAJA1	903.0
MAPK3	901.0
CCS	879.0
HM13	871.0
CLOCK	808.0
EP300	777.0
EPAS1	774.0
CXXC1	755.0
CCNA1	745.0
H3C1	733.0
H4C11	725.0
NPRL2	711.0
H4C5	654.0
RPS24	630.0
MDM2	617.0
NCOA1	595.0
RELA	572.0
UBE2D1	557.0
RPS13	553.0
CDC16	525.0
H2BC12	519.0
MED1	506.0
MRPL18	503.0
ACTR1A	495.0
RRAGC	489.0
NCOA2	417.0
H3C11	416.0
NR3C1	406.0
SEM1	329.0
TUBA1B	276.0
EZH2	243.0
ATF2	234.0
AAAS	206.0
EXOSC2	164.0
H4C4	162.0
HERPUD1	120.0
MRE11	94.0
RPL21	76.0
RPS3	69.0
WIPI1	38.0
MAP2K3	0.0
PSMB8	-53.0
DEPDC5	-78.0
NUP153	-100.0
COX8A	-109.0
CRYAB	-110.0
RPL4	-172.0
RLN1	-233.0
BRCA1	-237.0
ATP6V1H	-262.0
CREB1	-314.0
UBC	-323.0
VHL	-326.0
H3C8	-350.0
CAMK2G	-405.0
COX20	-406.0
HSPA12A	-409.0
PSMD5	-411.0
PGR	-473.0
CAPZB	-478.0
CUL7	-486.0
CDK6	-504.0
AKT3	-509.0
TGS1	-515.0
HSPB2	-533.0
PSMA5	-534.0
ANAPC1	-538.0
HSF1	-558.0
HBA2	-601.0
PRKCD	-615.0
RPS27	-651.0
H1-2	-661.0
RPL22	-684.0
MAPK14	-685.0
IMPACT	-712.0
RING1	-719.0
SRPRB	-731.0
PSMB9	-734.0
PSME4	-771.0
RRAGD	-797.0
PSMD11	-805.0
DCTN4	-808.0
NUP98	-843.0
RPS6KA2	-899.0
PHC3	-931.0
SRPRA	-937.0
MT1B	-979.0
PDIA6	-995.0
COX16	-1036.0
AGO4	-1047.0
NCF4	-1049.0
MBTPS1	-1052.0
RHEB	-1111.0
TATDN2	-1133.0
HSPH1	-1163.0
ATP6V0B	-1191.0
GSTP1	-1213.0
PTK6	-1231.0
TNRC6C	-1236.0
CDKN2A	-1239.0
MT1M	-1261.0
RPS18	-1287.0
EED	-1311.0
RPS8	-1337.0
NUP205	-1359.0
MAP3K5	-1368.0
BMT2	-1374.0
CAPZA1	-1417.0
HDAC3	-1583.0
TINF2	-1596.0
ATP6V1C2	-1609.0
CSRP1	-1756.0
RPL35	-1762.0
MAPK1	-1794.0
CDK4	-1880.0
LRPPRC	-1887.0
PSMD7	-1937.0
ATP6V1E1	-1938.0
RPL32	-2032.0
EXOSC3	-2039.0
E2F2	-2047.0
MEF2C	-2065.0
ME1	-2075.0
NFYC	-2086.0
TFDP1	-2145.0
TCIRG1	-2216.0
DCSTAMP	-2225.0
HSPA6	-2238.0
EXTL3	-2317.0
RPL18A	-2322.0
NUP210	-2340.0
TLR4	-2385.0
AGO3	-2452.0
CAPZA2	-2480.0
EP400	-2491.0
HSPB8	-2515.0
RPLP0	-2534.0
TFDP2	-2551.0
COX19	-2574.0
HMGA1	-2614.0
CCNE2	-2648.0
RORA	-2672.0
TPP1	-2691.0
TRIB3	-2707.0
EIF2AK4	-2726.0
NR1D1	-2835.0
PSMD9	-2906.0
RPS25	-2921.0
SLC7A11	-2939.0
ATF6	-2964.0
HIRA	-2981.0
NR3C2	-3037.0
ZBTB17	-3190.0
RPS6	-3203.0
SZT2	-3221.0
GRB10	-3225.0
LMNB1	-3282.0
RPL22L1	-3364.0
SOD3	-3366.0
LMNA	-3373.0
DNAJB6	-3423.0
DNAJB1	-3428.0
MAP2K7	-3436.0
MAPK10	-3465.0
ASF1A	-3475.0
KLHDC3	-3484.0
MAP2K4	-3501.0
ANAPC5	-3528.0
ANAPC15	-3556.0
HIGD1A	-3563.0
TUBA1A	-3578.0
MAPK11	-3633.0
PTGES3	-3640.0
H1-4	-3737.0
RPLP2	-3777.0
NCOA6	-3801.0
H4C6	-3817.0
TUBA3E	-3827.0
NCOR1	-3868.0
EHMT2	-3897.0
EIF2S1	-3972.0
RPL14	-3997.0
HSP90AA1	-4000.0
WFS1	-4072.0
TUBA1C	-4095.0
SIRT1	-4139.0
RPL12	-4199.0
MINK1	-4279.0
PHC2	-4284.0
RPL30	-4351.0
CCNA2	-4363.0
RPS15	-4386.0
SLC38A9	-4478.0
COX7A2L	-4486.0
PSMC3	-4492.0
H3C3	-4506.0
SERPINH1	-4545.0
CRTC1	-4552.0
APOB	-4556.0
CAMK2B	-4609.0
GSR	-4610.0
RPL31	-4613.0
FLCN	-4652.0
YWHAE	-4657.0
HSPA9	-4726.0
NDC1	-4745.0
NPRL3	-4766.0
H3-4	-4773.0
H2BC26	-4831.0
ATF3	-4852.0
HSPA4	-4869.0
TUBA3D	-4880.0
SUZ12	-4896.0
WDR59	-4998.0
RAD50	-5022.0
TERF2	-5078.0
NUP42	-5150.0
CBX6	-5151.0
NOTCH1	-5181.0
RANBP2	-5265.0
PSMD14	-5297.0
NUP37	-5314.0
SIN3B	-5393.0
H2AC18	-5415.5
H2AC19	-5415.5
CARM1	-5492.0
PSMD1	-5508.0
PSMD6	-5633.0
PSMF1	-5638.0
NUP93	-5736.0
FBXL17	-5744.0
CCAR2	-5797.0
MTOR	-5798.0
FABP1	-5910.0
HIF1AN	-5917.0
IGFBP7	-5937.0
H4C13	-6090.0
IGFBP1	-6107.0
EXOSC9	-6121.0
NUP54	-6131.0
RPS26	-6416.0
AKT2	-6463.0
RPS27A	-6484.0
CABIN1	-6536.0
COX4I1	-6540.0
PSMA8	-6587.0
PSMC4	-6643.0
GCN1	-6697.0
MLST8	-6702.0
DNAJA4	-6754.0
ATP6V0D1	-6764.0
CRYBA4	-6796.0
SEC13	-6814.0
RBX1	-6897.0
NOX5	-6948.0
RPL3L	-6960.0
TNFRSF21	-6965.0
LAMTOR3	-7041.0
ATP6V1E2	-7061.0
EIF2AK1	-7065.0
DCTN3	-7114.0
H2BC14	-7223.0
PSMA4	-7243.0
HSPA12B	-7323.0
TUBB2B	-7326.0
RPL8	-7369.0
RPL23A	-7390.0
RPL5	-7510.0
PRDX2	-7552.0
H2BC13	-7559.0
MT4	-7670.0
CCNE1	-7855.0
RPL3	-7876.0
NPAS2	-7900.0
H2AC14	-7938.0
DPP3	-7945.0
H4C9	-8005.0
EIF2S2	-8052.0
CLEC1B	-8056.0
BAG3	-8215.0
RPL10L	-8234.0
GSTA3	-8259.0
TPR	-8306.0
PLA2G4B	-8352.0
HIF3A	-8456.0
PRDX3	-8479.0
ARFGAP1	-8509.0
SH3BP4	-8521.0
GPX6	-8644.0
TUBB8	-8794.0
WDR24	-8828.0
ALB	-8941.0
RPL13A	-9002.5
IL1A	-9007.0
ATP6V1B1	-9062.0
CAPZA3	-9138.0
TRIM21	-9335.0
RPL7A	-9413.0
PSMB11	-9711.0
CAMK2A	-9993.0
DDX11	-10112.0
GSTA1	-10436.0

---

REACTOME_KERATINIZATION

REACTOME_KERATINIZATION

	1073
set	REACTOME_KERATINIZATION
setSize	210
pANOVA	3.45e-14
s.dist	-0.303
p.adjustANOVA	1.13e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
LCE2B	-10451
KRTAP15-1	-10425
KRTAP11-1	-10303
KRTAP19-5	-10290
SPRR3	-10237
KRT15	-10219
KRTAP1-3	-10209
KRTAP5-10	-10132
KRTAP17-1	-10117
KRT17	-10076
KRTAP6-2	-10068
KRTAP5-9	-10031
LCE1F	-10016
KRT76	-9936
KRT73	-9926
KRTAP4-5	-9895
KRT82	-9873
KRT24	-9855
KRT35	-9819
KRT80	-9794

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
LCE2B	-10451
KRTAP15-1	-10425
KRTAP11-1	-10303
KRTAP19-5	-10290
SPRR3	-10237
KRT15	-10219
KRTAP1-3	-10209
KRTAP5-10	-10132
KRTAP17-1	-10117
KRT17	-10076
KRTAP6-2	-10068
KRTAP5-9	-10031
LCE1F	-10016
KRT76	-9936
KRT73	-9926
KRTAP4-5	-9895
KRT82	-9873
KRT24	-9855
KRT35	-9819
KRT80	-9794
PI3	-9793
KRTAP2-2	-9754
DSG4	-9712
LCE3D	-9696
TGM5	-9666
KRT4	-9591
KRTAP2-1	-9565
KRT79	-9536
LIPK	-9475
KRTAP9-9	-9455
KRT20	-9394
LCE5A	-9383
KRTAP6-3	-9380
KRT23	-9368
KRTAP25-1	-9366
KRT26	-9364
LCE1B	-9354
KRTAP24-1	-9342
KRTAP4-1	-9315
KRT33B	-9260
RPTN	-9250
KRT6A	-9098
KRTAP4-2	-9043
KRTAP22-1	-9042
KRT6B	-9026
KRTAP9-3	-8992
KRTAP1-1	-8974
PKP3	-8966
KRTAP10-9	-8959
LCE4A	-8876
KRT75	-8853
KLK14	-8847
TGM1	-8766
KRTAP13-2	-8761
KRTAP19-1	-8750
KRT78	-8694
KRT85	-8651
KRTAP21-2	-8618
KRTAP13-3	-8579
KRTAP5-2	-8568
EVPL	-8563
LELP1	-8514
KRTAP10-5	-8425
KRTAP29-1	-8387
CDSN	-8228
DSC1	-8150
KRTAP21-3	-8129
KRTAP10-2	-8092
KRTAP10-11	-8066
KRT34	-8059
KRT28	-7854
KRT32	-7834
KRTAP19-7	-7792
KRT6C	-7491
DSG1	-7415
KRTAP4-6	-7363
PCSK6	-7348
KRT83	-7261
JUP	-7211
KAZN	-7200
KRTAP3-3	-7173
KRTAP13-4	-7112
KRTAP10-10	-7098
IVL	-7050
DSG3	-6846
SPINK5	-6753
LCE2C	-6612
KRTAP5-4	-6488
KRT77	-6271
KRTAP1-5	-6238
KRTAP10-3	-5889
LCE3B	-5860
CELA2A	-5778
KRT33A	-5777
KRT5	-5536
FLG	-5381
KRT39	-5370
KRTAP12-4	-5368
KRTAP9-1	-5326
KRTAP5-3	-5219
SPRR2A	-5202
LIPN	-5182
SPRR1B	-5176
SPRR2F	-5139
SPRR2G	-5098
KLK12	-5091
KRTAP10-7	-5049
KRTAP6-1	-4999
PKP2	-4810
KRTAP19-8	-4664
ST14	-4509
KRT38	-4377
KRTAP16-1	-4182
KRTAP10-4	-4048
KRTAP12-1	-3825
KRT74	-3694
LCE2A	-3624
KRT2	-3510
KRTAP26-1	-3457
KRTAP23-1	-3090
KRT71	-2998
KRT9	-2972
KRTAP19-2	-2750
CASP14	-2695
KRT36	-2364
KRTAP20-1	-2295
KRT27	-2264
SPRR1A	-2221
SPRR2D	-2054
KRTAP12-3	-2031
LCE3E	-1888
KRT25	-1864
KRT81	-1780
KRTAP1-4	-1749
KRTAP10-1	-1272
KRT7	-1194
KRT86	-1145
FURIN	-1134
KRTAP5-5	-854
PKP4	-709
KRTAP5-8	-494
LCE1A	-487
KRT12	-403
KRT13	-293
KRTAP4-3	-285
KRTAP3-1	-264
KRTAP20-2	135
KRTAP3-2	221
PPL	555
SPINK9	559
KRT18	1002
KRTAP10-12	1072
KRTAP9-2	1179
KLK8	1270
KRT10	1640
KRTAP2-4	1752
KRT8	1818
KRT31	2030
KRT3	2044
TCHH	2220
KRTAP4-7	2290
KRT14	2464
LCE1C	2554
DSC2	2686
KRT84	3103
PKP1	3395
KLK5	3597
DSG2	4366
SPINK6	4699
KRT72	5076
KRTAP19-6	5137
KRT40	5190
KRTAP10-6	5537
CAPN1	5593
KRTAP13-1	5649
KRTAP5-1	6145
KRTAP8-1	6158
KRT37	6385
CSTA	6499
LCE6A	6510
DSP	6839
LCE2D	6880
PERP	6942
LCE1E	7013
CAPNS1	7220
PRSS8	7375
KRTAP9-6	7851
KRT19	7958
KRTAP9-4	7966
KRTAP4-4	8500
KRTAP19-3	8561
KRTAP10-8	8888
KRTAP2-3	9143
KRTAP4-8	9256
KLK13	9610
DSC3	9650
KRTAP5-7	9681
KRT1	9728
KRT16	10020
KRTAP12-2	10030
KRTAP27-1	10096
LIPM	10250
SPRR2E	10444
KRTAP5-6	10746
LIPJ	10763
KRTAP19-4	10834
KRTAP5-11	10906
KRTAP21-1	11073
LCE3A	11232
KRTAP4-11	11485

---

REACTOME_CELL_CYCLE

REACTOME_CELL_CYCLE

	190
set	REACTOME_CELL_CYCLE
setSize	666
pANOVA	2.1e-10
s.dist	0.144
p.adjustANOVA	5.74e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CHMP4C	11134
USO1	10970
CSNK1E	10909
H3-3A	10816
CDKN2D	10796
PPP2R5B	10604
MZT2B	10599
H2AC4	10558
CDC25C	10524
MIS18A	10519
H2BC17	10497
MYBL2	10417
TUBB4B	10395
H4C16	10315
H2BC15	10314
POLE2	10284
CTDNEP1	10173
RAN	10098
H3-3B	10095
H4C3	10086

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CHMP4C	11134.0
USO1	10970.0
CSNK1E	10909.0
H3-3A	10816.0
CDKN2D	10796.0
PPP2R5B	10604.0
MZT2B	10599.0
H2AC4	10558.0
CDC25C	10524.0
MIS18A	10519.0
H2BC17	10497.0
MYBL2	10417.0
TUBB4B	10395.0
H4C16	10315.0
H2BC15	10314.0
POLE2	10284.0
CTDNEP1	10173.0
RAN	10098.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
PSMD13	10036.0
TUBG1	10027.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
NSL1	9840.0
CDK11A	9802.0
CSNK2A1	9778.0
SGO1	9752.0
BABAM1	9748.0
H3C12	9726.0
H2BC21	9693.0
ANAPC10	9626.0
BRCA2	9605.0
PHLDA1	9532.0
HSPA2	9522.0
KIF20A	9474.0
POM121	9464.0
BIRC5	9463.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
POLR2C	9358.0
NEK6	9352.0
TUBB6	9322.0
REC8	9274.0
UBE2S	9214.0
TUBG2	9179.0
CCNB1	9175.0
CDKN2B	9139.0
SIRT2	9130.0
MASTL	9071.0
CKS1B	9069.0
CDKN2C	9068.0
H2AZ1	9026.0
H2AC20	9019.0
RAB1B	8943.0
UBB	8935.0
KMT5A	8915.0
RNF8	8912.0
E2F5	8896.0
GAR1	8831.0
AURKA	8822.0
POLE4	8745.0
TEN1	8743.0
CENPC	8675.0
HAUS2	8672.0
PSMA6	8609.0
CDC23	8577.0
PCNA	8551.0
GINS1	8549.0
DSCC1	8531.0
POLR2G	8490.0
ZW10	8484.0
TUBA4B	8469.0
CENPH	8445.0
ORC2	8430.0
KPNB1	8399.0
ORC6	8363.0
DYNC1LI2	8336.0
ABRAXAS1	8286.0
TNPO1	8276.0
BARD1	8265.0
POLE3	8257.0
PSMC6	8173.0
CCNH	8147.0
TP53BP1	8084.0
CDC26	8079.0
UBE2N	8070.0
RAE1	8059.0
CENPS	8051.0
NUP58	8047.0
GINS4	8021.0
TUBA8	8019.0
CEP41	8012.0
KIF23	8000.0
TP53	7995.0
E2F1	7979.0
NUP43	7960.0
POLD4	7923.0
RPA3	7810.0
NUP35	7791.0
PSME3	7776.0
CEP43	7761.0
NUP50	7744.0
BLZF1	7717.0
RPA2	7679.0
H3C4	7677.0
DAXX	7619.0
MDM4	7582.0
RCC1	7522.0
LIN9	7497.0
RAD9B	7481.0
TUBB4A	7468.0
SHQ1	7457.0
PPP2R5A	7419.0
CTC1	7412.0
NEDD1	7410.0
UBE2E1	7409.0
TUBA4A	7384.0
H2BC11	7363.0
H2BC5	7354.0
HMMR	7237.0
CHMP2A	7210.0
NCAPG	7209.0
DCTN1	7164.0
NME7	7129.0
RFC4	7122.0
MYC	7102.0
LIN37	7094.0
POLD1	7018.0
CENPW	7015.0
WRN	6947.0
CHMP4A	6900.0
ORC1	6899.0
MCPH1	6889.0
DYNLL2	6886.0
H2BC3	6877.0
TUBB3	6871.0
WRAP53	6868.0
HSP90AB1	6865.0
CEP250	6859.0
CENPA	6857.0
HAUS1	6787.0
CHMP2B	6780.0
PSMB3	6752.0
CDK7	6742.0
GINS2	6674.0
PSMD12	6656.0
NUMA1	6650.0
CDCA8	6641.0
YWHAQ	6594.0
ANKRD28	6566.0
NUP88	6529.0
RBBP8	6518.0
SYCE2	6507.0
LYN	6506.0
H4C1	6505.0
PLK4	6498.0
FBXL18	6456.0
DYNC1LI1	6419.0
CENPT	6418.0
AJUBA	6380.0
EXO1	6320.0
CENPM	6270.0
MCM2	6216.0
POLD2	6199.0
DBF4	6178.0
CSNK2B	6147.0
ANAPC7	6124.0
PSMB7	6049.0
NUP155	6039.0
RMI1	6032.0
RBBP4	6026.0
XPO1	5947.0
SPAST	5932.0
POLR2I	5881.0
BLM	5877.0
LPIN1	5850.0
H4C2	5849.0
H2AJ	5832.0
H2AX	5821.0
KAT5	5792.0
ANAPC2	5784.0
ESCO2	5749.0
RFC5	5739.0
VRK2	5692.0
CHMP7	5637.0
SDCCAG8	5605.0
H4C12	5591.0
ANAPC11	5571.0
YWHAH	5488.0
LIN52	5471.0
CDK1	5463.0
PSMC1	5452.0
DSN1	5434.0
PIAS4	5432.0
PPP2R1A	5421.0
FZR1	5395.0
CKAP5	5383.0
H4C8	5375.0
SET	5356.0
TUBB2A	5342.0
TUBA3C	5315.0
ZWILCH	5257.0
VPS4A	5230.0
CDK5RAP2	5227.0
CDK11B	5212.0
PRKCB	5164.0
PSMD8	5087.0
PPP6C	5034.0
POT1	5008.0
ATM	4998.0
CSNK2A2	4931.0
ANAPC16	4927.0
NDE1	4740.0
KIF18A	4714.0
RAB1A	4671.0
CDKN1B	4666.0
NPM1	4661.0
BANF1	4658.0
PPP2R5C	4656.0
PSMB10	4635.0
ENSA	4581.0
DHFR	4551.0
BTRC	4547.0
ORC5	4541.0
TAOK1	4538.0
CDCA5	4511.0
CCND3	4481.0
PIF1	4477.0
PSMD3	4433.0
CDC27	4430.0
UBE2C	4394.0
CDKN1A	4380.0
CENPE	4344.0
ORC4	4334.0
DYNC1H1	4333.0
AURKB	4328.0
DYNC1I1	4315.0
H3C6	4303.0
PSMA3	4156.0
CUL1	4104.0
GSK3B	4062.0
H2AZ2	4022.0
RHNO1	4015.0
RAB2A	4004.0
CABLES1	3994.0
TUBGCP4	3974.0
SMARCA5	3945.0
ZNF385A	3879.0
PSMC2	3840.0
GORASP2	3821.0
SYCP3	3802.0
B9D2	3791.0
HAUS4	3783.0
PMF1	3768.0
RAD17	3742.0
TPX2	3724.0
TUBB	3708.0
MZT2A	3702.0
CEP290	3693.0
ATR	3678.0
DYNC1I2	3671.0
YWHAZ	3670.0
NDC80	3635.0
NUP133	3627.0
ESPL1	3625.0
CLASP1	3593.0
NUP160	3568.0
COP1	3561.0
SRC	3558.0
OIP5	3543.0
ACD	3521.5
PCM1	3462.0
RBL2	3425.0
POLR2K	3416.0
LCMT1	3402.0
CEP152	3343.0
CDC45	3327.0
CEP63	3302.0
FBXW11	3290.0
NUP214	3289.0
SPC24	3282.0
YWHAG	3187.0
CHMP3	3159.0
DCTN2	3142.0
PSMC5	3099.0
HDAC1	3086.0
CEP57	3058.0
UIMC1	3022.0
CDT1	2997.0
NUP188	2995.0
CLASP2	2994.0
CDK2	2988.0
CEP70	2984.0
DYRK1A	2980.0
UBA52	2963.0
PSMB1	2960.0
SSNA1	2919.0
TYMS	2878.0
PCNT	2859.0
MSH5	2845.0
ANAPC4	2830.0
DNA2	2805.0
POLR2B	2795.0
SKP2	2789.0
LPIN2	2771.0
KNL1	2766.0
CEP76	2739.0
AKAP9	2716.0
H2BC1	2654.0
LBR	2649.0
PPP6R3	2603.0
ABL1	2597.0
PSMB2	2596.0
STAG1	2592.0
CHEK1	2585.0
H3C10	2553.0
CCNB2	2521.0
MZT1	2513.0
PSMA1	2497.0
RUVBL2	2479.0
PSMB5	2455.0
PSMD2	2443.0
PSMA7	2417.0
MLH3	2414.0
RAD51	2407.0
PPME1	2396.0
AKT1	2390.0
SYNE2	2378.0
BABAM2	2351.0
DYNLL1	2349.0
TERF2IP	2334.0
CCND1	2318.0
SEH1L	2309.0
PLK1	2308.0
SMC4	2289.0
PSMB4	2281.0
DIDO1	2258.0
PRKCA	2239.0
RAD1	2227.0
STAG3	2211.0
CDKN1C	2152.0
LIG1	2069.0
PSMD4	2042.0
H2BC10	2021.0
WEE1	2003.0
PPP1CB	1956.0
SUN2	1943.0
ODF2	1921.0
GINS3	1900.0
RPA1	1885.0
RAB8A	1869.0
BORA	1864.0
PPP2CA	1855.0
E2F3	1797.0
RFC2	1760.0
LIN54	1733.0
BUB1B	1694.0
ATRIP	1661.0
MNAT1	1602.0
CENPO	1592.0
KIF2C	1583.0
PSME1	1571.0
TOPBP1	1558.0
MAPRE1	1549.0
SKP1	1543.0
POLR2A	1481.0
NEK2	1458.0
NUP107	1453.0
NCAPD3	1434.0
PDS5A	1397.0
RB1	1335.0
MIS18BP1	1332.0
RMI2	1319.0
SMC2	1295.0
SFN	1261.0
PSME2	1245.0
NEK7	1231.0
RUVBL1	1222.0
SUN1	1219.0
PSMA2	1218.0
CENPQ	1164.0
PSMB6	1163.0
POM121C	1147.0
E2F6	1123.0
NUP62	1081.0
NBN	1064.0
TUBB1	1042.0
NCAPG2	1015.0
FEN1	994.0
TERF1	989.0
NUP85	973.0
TUBAL3	971.0
POLE	963.0
CNTRL	908.0
MAPK3	901.0
RFC3	822.0
SYNE1	801.0
LEMD3	798.0
IST1	783.0
EP300	777.0
CCNA1	745.0
RCC2	742.0
H3C1	733.0
H4C11	725.0
TEX12	694.0
H4C5	654.0
MDM2	617.0
CSNK1D	610.0
SYCE1	563.0
UBE2D1	557.0
CDC16	525.0
H2BC12	519.0
MAD1L1	516.0
ACTR1A	495.0
PHF20	457.0
POLR2E	455.0
TUBGCP3	441.0
H3C11	416.0
POLR2H	334.0
SEM1	329.0
TUBA1B	276.0
CCP110	211.0
PPP1R12A	209.0
AAAS	206.0
H4C4	162.0
PAFAH1B1	139.0
MRE11	94.0
POLA2	56.0
MCM6	47.0
RAD21	23.0
CCND2	11.0
PSMB8	-53.0
PDS5B	-69.0
NUP153	-100.0
SPO11	-145.0
TUBGCP2	-185.0
CDC6	-211.0
BRCA1	-237.0
CEP72	-254.0
MIS12	-257.0
UBC	-323.0
H3C8	-350.0
PPP2R1B	-352.0
ARPP19	-377.0
PSMD5	-411.0
CENPL	-455.0
JAK2	-474.0
KNTC1	-501.0
CDK6	-504.0
AKT3	-509.0
PSMA5	-534.0
ANAPC1	-538.0
ESCO1	-550.0
POLR2F	-559.0
PPP2R2A	-603.0
MAX	-612.0
RPS27	-651.0
ANKLE2	-687.0
PSMB9	-734.0
TOP3A	-739.0
PSME4	-771.0
PSMD11	-805.0
RFC1	-815.0
ORC3	-828.0
NUP98	-843.0
CEP131	-860.0
SGO2	-877.0
MCM3	-889.0
PSMC3IP	-984.0
CLIP1	-1032.0
HUS1	-1084.0
PPP2R5E	-1166.0
PTK6	-1231.0
CDKN2A	-1239.0
MDC1	-1241.0
EML4	-1280.0
MCM4	-1286.0
NDEL1	-1297.0
NUP205	-1359.0
RTEL1	-1361.0
GMNN	-1366.0
HAUS8	-1392.0
ALMS1	-1415.0
FOXM1	-1454.0
SKA2	-1465.0
CENPN	-1557.0
STN1	-1566.0
TINF2	-1596.0
PPP2R5D	-1720.0
HAUS6	-1764.0
MAPK1	-1794.0
NEK9	-1833.0
CDK4	-1880.0
PPP1CC	-1885.0
CDC25B	-1894.0
VRK1	-1901.0
PSMD7	-1937.0
TUBGCP6	-1945.0
BRIP1	-1946.0
E2F2	-2047.0
RBL1	-2049.0
POLR2D	-2050.0
NCAPD2	-2122.0
HJURP	-2130.0
TFDP1	-2145.0
RNF168	-2213.0
PTTG1	-2237.0
NUP210	-2340.0
CC2D1B	-2395.0
YWHAB	-2453.0
NOP10	-2457.0
NUDC	-2458.0
TOP2A	-2478.0
CDC14A	-2512.0
HAUS3	-2539.0
TFDP2	-2551.0
CCNE2	-2648.0
PPP1R12B	-2770.0
NUF2	-2839.0
PSMD9	-2906.0
PRIM2	-2930.0
MCM8	-2989.0
MLH1	-2991.0
SUMO1	-3031.0
AHCTF1	-3049.0
MCM5	-3052.0
CDC20	-3146.0
MAU2	-3169.0
FBXO5	-3238.0
BUB3	-3248.0
NSD2	-3278.0
PRKACA	-3280.0
LMNB1	-3282.0
CHTF8	-3309.0
RAD9A	-3359.0
LMNA	-3373.0
POLR2L	-3453.0
PRKAR2B	-3491.0
ANAPC5	-3528.0
ANAPC15	-3556.0
TUBA1A	-3578.0
BUB1	-3658.0
CEP164	-3729.0
H4C6	-3817.0
TUBA3E	-3827.0
PPP2R2D	-3904.0
CEP135	-3908.0
FBXL7	-3947.0
TUBGCP5	-3955.0
HSP90AA1	-4000.0
SKA1	-4015.0
DMC1	-4050.0
TUBA1C	-4095.0
FKBP6	-4218.0
SPDL1	-4219.0
MAD2L1	-4227.0
NHP2	-4228.0
PCBP4	-4281.0
KIF2B	-4290.0
ITGB3BP	-4330.0
CCNA2	-4363.0
CHMP4B	-4388.0
MND1	-4471.0
PSMC3	-4492.0
H3C3	-4506.0
LPIN3	-4588.0
PPP2CB	-4627.0
YWHAE	-4657.0
CHTF18	-4677.0
NIPBL	-4687.0
MCM7	-4735.0
NDC1	-4745.0
H3-4	-4773.0
RRM2	-4822.0
H2BC26	-4831.0
CENPU	-4840.0
TUBA3D	-4880.0
UBE2V2	-4928.0
CEP192	-4953.0
CEP78	-4974.0
SPC25	-4986.0
RAD50	-5022.0
RSF1	-5031.0
HAUS5	-5034.0
TERF2	-5078.0
FKBPL	-5124.0
CDC25A	-5146.0
NUP42	-5150.0
TK1	-5191.0
TEX15	-5249.0
RANBP2	-5265.0
NINL	-5271.0
PSMD14	-5297.0
NUP37	-5314.0
CENPF	-5361.0
HERC2	-5391.0
H2AC18	-5415.5
H2AC19	-5415.5
CLSPN	-5454.0
SMC1B	-5462.0
TMPO	-5468.0
PSMD1	-5508.0
PSMD6	-5633.0
CDC7	-5634.0
PSMF1	-5638.0
NCAPH	-5690.0
NUP93	-5736.0
SFI1	-5747.0
RANGAP1	-5823.0
CENPK	-5871.0
CENPP	-5908.0
CHEK2	-5952.0
LEMD2	-6049.0
GOLGA2	-6063.0
H4C13	-6090.0
NUP54	-6131.0
SMC3	-6169.0
WAPL	-6268.0
OPTN	-6314.0
ZWINT	-6341.0
CENPJ	-6375.0
AKT2	-6463.0
RPS27A	-6484.0
PRDM9	-6557.0
PSMA8	-6587.0
PSMC4	-6643.0
SEC13	-6814.0
SYCP2	-6838.0
GORASP1	-6885.0
RBX1	-6897.0
MSH4	-7089.0
MCM10	-7100.0
POLD3	-7106.0
DCTN3	-7114.0
CNEP1R1	-7168.0
H2BC14	-7223.0
PSMA4	-7243.0
TUBB2B	-7326.0
GTSE1	-7362.0
KIF2A	-7387.0
TERT	-7404.0
CHMP6	-7414.0
H2BC13	-7559.0
E2F4	-7591.0
UBE2I	-7598.0
PRIM1	-7751.0
CCNE1	-7855.0
H2AC14	-7938.0
H4C9	-8005.0
SYCE3	-8221.0
TPR	-8306.0
INCENP	-8317.0
NCAPH2	-8346.0
PKMYT1	-8763.0
TUBB8	-8794.0
SYCP1	-9104.0
RAD51C	-9702.0
PSMB11	-9711.0
POLR2J	-10431.0

---

REACTOME_METABOLISM_OF_RNA

REACTOME_METABOLISM_OF_RNA

	1313
set	REACTOME_METABOLISM_OF_RNA
setSize	675
pANOVA	4.02e-10
s.dist	0.141
p.adjustANOVA	9.43e-08

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MRM1	11297
TNFSF13	11295
GEMIN2	11012
LENG1	10994
CSNK1E	10909
BMS1	10896
SYMPK	10779
RBM8A	10482
RPL26	10476
PDCD7	10457
SNRNP25	10402
FAM32A	10341
MPHOSPH10	10321
RPL10A	10291
TRMT10A	10278
NXT1	10259
RPS16	10188
NXF1	10176
CNOT8	10145
ADAT3	10128

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MRM1	11297.0
TNFSF13	11295.0
GEMIN2	11012.0
LENG1	10994.0
CSNK1E	10909.0
BMS1	10896.0
SYMPK	10779.0
RBM8A	10482.0
RPL26	10476.0
PDCD7	10457.0
SNRNP25	10402.0
FAM32A	10341.0
MPHOSPH10	10321.0
RPL10A	10291.0
TRMT10A	10278.0
NXT1	10259.0
RPS16	10188.0
NXF1	10176.0
CNOT8	10145.0
ADAT3	10128.0
RAN	10098.0
SMU1	10088.0
PSMD13	10036.0
CLP1	10002.0
PAIP1	10000.0
UTP20	9911.0
CSTF3	9859.0
SNRPA1	9821.0
TRMT61A	9808.0
RPL39L	9799.0
RPL36AL	9794.5
RPL29	9738.0
NSUN2	9699.0
SRSF12	9695.0
CCDC12	9690.0
POP7	9637.0
HSPA8	9600.0
XRN2	9599.0
THOC6	9539.0
PPIH	9512.0
DCP2	9485.0
RBM22	9476.0
POM121	9464.0
EXOSC5	9427.0
NT5C3B	9375.0
POLR2C	9358.0
DIS3	9332.0
APOBEC3A	9302.0
RPPH1	9093.0
USP39	9084.0
PPIL1	9009.0
LSM11	8987.0
C2orf49	8941.0
UBB	8935.0
DHX16	8909.0
TP53RK	8899.0
RPL27	8846.0
GAR1	8831.0
RPS28	8785.0
SNRPD2	8773.0
RPP40	8768.0
LSM8	8757.0
CWC22	8751.0
NOL12	8748.0
SKIC8	8720.0
ZFP36	8694.0
ISY1	8665.0
PSMA6	8609.0
SLBP	8576.0
POLR2G	8490.0
DDX5	8460.0
TRMT11	8458.0
RPL37A	8438.0
RPL26L1	8414.0
PRKRIP1	8323.0
TNPO1	8276.0
NOP14	8212.0
SMNDC1	8193.0
RPS19	8176.0
PSMC6	8173.0
CWC15	8158.0
SNRPF	8155.0
CCNH	8147.0
MPHOSPH6	8118.0
LSM3	8113.0
UTP15	8098.0
SNRPA	8096.0
RAE1	8059.0
NUP58	8047.0
NOL9	8039.0
RPL15	7977.0
SENP3	7973.0
NUP43	7960.0
RRP36	7953.0
ZBTB8OS	7943.0
SF3B2	7933.0
RPL6	7932.0
HNRNPF	7894.0
WDR3	7834.0
TYW1	7809.0
NUP35	7791.0
RPL34	7790.0
PSME3	7776.0
CNOT6	7759.0
THOC1	7757.0
DDX52	7753.0
NUP50	7744.0
ADAR	7680.0
SNRNP48	7651.0
RPS3A	7611.0
HSPA1A	7602.0
RPS27L	7580.0
TRMT1	7567.0
LSM6	7527.0
RRP7A	7524.0
SF3A3	7502.0
TRMT61B	7495.0
DDX21	7483.0
RRP9	7455.0
LSM10	7451.0
DDX1	7449.0
RPL23	7379.0
RPL35A	7327.0
PAN2	7324.0
RIOK3	7316.0
CPSF7	7303.0
GEMIN5	7284.0
CNOT6L	7270.0
MRM3	7246.0
CTU1	7232.0
SRSF8	7195.0
RPL28	7186.0
ALYREF	7137.0
NOP2	7077.0
ANP32A	7055.0
RPL11	7034.0
MAPKAPK2	7010.0
BCAS2	6989.0
PRPF4	6944.0
ZNF830	6897.0
THUMPD1	6891.0
DIMT1	6835.0
LCMT2	6817.0
RPS15A	6793.0
CNOT4	6774.0
ZMAT5	6753.0
PSMB3	6752.0
CDK7	6742.0
SRSF6	6736.0
HNRNPA1	6725.0
TRDMT1	6714.0
PRCC	6707.0
SNRNP70	6680.0
PSMD12	6656.0
BOP1	6653.0
SRSF5	6621.0
RPL41	6591.0
SMG6	6585.0
RPLP1	6550.0
WDR77	6543.0
NUP88	6529.0
HNRNPR	6528.0
FAU	6502.0
RTRAF	6485.0
KRR1	6436.0
GLE1	6416.0
HNRNPM	6399.0
SDE2	6393.0
RPL24	6382.0
U2AF1L4	6378.0
DUS2	6331.0
SARNP	6326.0
SNUPN	6309.0
SRSF10	6300.0
RPS5	6275.0
CWC27	6263.0
NOL11	6144.0
C1D	6136.0
EIF4E	6127.0
BUD31	6123.0
PSMB7	6049.0
NUP155	6039.0
SNRPG	6029.0
EDC3	5997.0
ACIN1	5984.0
SNRNP27	5958.0
XPO1	5947.0
PHF5A	5924.0
CPSF3	5889.0
POLR2I	5881.0
LSM5	5866.0
MFAP1	5854.0
PDCD11	5814.0
APOBEC1	5789.0
RPL7	5777.0
CNOT2	5693.0
FTSJ3	5683.0
FYTTD1	5663.0
EXOSC8	5657.0
RPP30	5577.0
PAN3	5542.0
TSEN34	5536.0
ZFP36L1	5509.0
RPS29	5507.0
HSPB1	5499.0
UTP25	5487.0
EXOSC1	5477.0
PSMC1	5452.0
PPP2R1A	5421.0
PRPF40A	5406.0
RPL36	5403.0
APOBEC2	5391.0
NAT10	5378.0
PES1	5363.0
SET	5356.0
EPRS1	5355.0
NSUN4	5349.0
WBP11	5348.0
SF3B3	5337.0
RPS11	5323.0
PPIL3	5276.0
GCFC2	5251.0
YJU2	5145.0
CASC3	5144.0
PSMD8	5087.0
GTF2H5	5045.0
RPS20	4993.0
RPS10	4983.0
EXOSC7	4975.0
RPS9	4917.0
SF1	4906.0
POP1	4871.0
RPL37	4854.0
RPL27A	4853.0
MTERF4	4824.0
PATL1	4810.0
SRSF7	4744.0
EIF4B	4729.0
EXOSC4	4711.0
HNRNPL	4704.0
PSMB10	4635.0
PRPF8	4623.0
HNRNPU	4612.0
TRMT5	4607.0
WBP4	4601.0
IK	4588.0
UTP6	4573.0
RBM7	4509.0
THOC3	4495.0
APOBEC3C	4452.0
PRMT5	4449.0
PSMD3	4433.0
HNRNPK	4410.0
DDX46	4386.0
RPL18	4341.0
RPS23	4307.0
ALKBH8	4282.0
CNOT3	4227.0
SUGP1	4214.0
RPL9	4204.0
DDX20	4163.0
PSMA3	4156.0
UBL5	4068.0
WDR75	4049.0
UTP18	4026.0
TRA2B	3975.0
NCBP1	3972.0
GEMIN6	3957.0
RPS21	3934.0
FBL	3931.0
LSM1	3895.0
TRMT112	3862.0
PSMC2	3840.0
PCBP2	3760.0
PPIG	3716.0
YWHAZ	3670.0
NUP133	3627.0
RPS12	3607.0
SF3A2	3594.0
NUP160	3568.0
SNRPN	3550.0
MTO1	3496.0
RPL17	3492.0
IMP3	3455.0
POLR2K	3416.0
ZNF473	3407.0
C9orf78	3359.0
ISG20L2	3315.0
CNOT9	3310.0
NUP214	3289.0
RBM42	3257.0
LSM4	3256.0
HNRNPD	3235.0
CNOT11	3226.0
DHX9	3196.0
GTPBP3	3157.0
RIOK2	3147.0
QTRT1	3135.0
TRMT10C	3108.0
PSMC5	3099.0
SRSF3	3016.0
NUP188	2995.0
KHSRP	2966.0
PABPN1	2964.0
UBA52	2963.0
PSMB1	2960.0
RPL13	2937.0
TSEN15	2922.0
EBNA1BP2	2891.0
CPSF6	2857.0
FUS	2846.0
U2SURP	2825.0
RPSA	2801.0
POLR2B	2795.0
PARN	2660.0
OSGEP	2643.0
CHERP	2609.0
PSMB2	2596.0
PPIL4	2537.0
GSPT1	2524.0
TCERG1	2504.0
PSMA1	2497.0
PSMB5	2455.0
PSMD2	2443.0
PSMA7	2417.0
RBM5	2392.0
AKT1	2390.0
EMG1	2384.0
SNW1	2377.0
RPP21	2371.0
DHX37	2310.0
SEH1L	2309.0
TRMT44	2285.0
PSMB4	2281.0
SNRPC	2273.0
RNMT	2264.0
RPP25	2251.0
PRKCA	2239.0
PPIL2	2235.0
SKIC3	2207.0
WDR70	2201.0
RBM17	2131.0
SYF2	2107.0
TPRKB	2104.0
ZC3H11A	2076.0
HBS1L	2072.0
WDR33	2071.0
EXOSC6	2061.0
PSMD4	2042.0
CDC40	1999.0
PRORP	1995.0
RPL38	1935.0
EIF4A3	1929.0
TUT4	1910.0
RPL19	1906.0
PPP2CA	1855.0
RBM39	1769.0
CSTF2T	1767.0
SNRNP40	1762.0
SF3B4	1743.0
GTF2H3	1736.0
PNN	1697.0
CSTF1	1690.0
ERI1	1674.0
POP5	1638.0
MNAT1	1602.0
PSME1	1571.0
PRPF18	1535.0
RBM28	1496.0
POLR2A	1481.0
ADARB1	1466.0
NUP107	1453.0
PRPF38A	1437.0
PCBP1	1367.0
TXNL4A	1349.0
RPP38	1329.0
CWF19L2	1309.0
RPS7	1305.0
CACTIN	1281.0
RPS2	1277.0
MTREX	1266.0
PSME2	1245.0
CRNKL1	1229.0
PSMA2	1218.0
TSEN54	1212.0
ZCRB1	1202.0
GNL3	1197.0
WDR43	1183.0
PSMB6	1163.0
CTNNBL1	1157.0
POM121C	1147.0
TFIP11	1109.0
NUP62	1081.0
WDR46	1065.0
HNRNPA3	1056.0
UTP4	990.0
NUP85	973.0
SNRPE	966.0
RPS14	948.0
NOB1	928.0
WDR12	905.0
SNRNP35	846.0
NCL	836.0
POP4	831.0
TRNT1	789.0
HNRNPH1	700.0
RPS24	630.0
GEMIN7	612.0
CSNK1D	610.0
DCP1A	578.0
GEMIN4	573.0
RPS13	553.0
CNOT10	478.0
ADAT1	459.0
POLR2E	455.0
NCBP2	442.0
UTP3	362.0
POLR2H	334.0
XAB2	332.0
SEM1	329.0
WDR18	271.0
YBX1	223.0
AAAS	206.0
IGF2BP3	181.0
EXOSC2	164.0
PELP1	99.0
RPL21	76.0
RPS3	69.0
LTV1	54.0
SNIP1	1.0
PSMB8	-53.0
NUP153	-100.0
DCPS	-118.0
PPP1R8	-124.0
THADA	-129.0
PCF11	-153.0
PNO1	-170.0
RPL4	-172.0
FAM98B	-193.0
SF3B6	-250.0
PRPF31	-278.0
EFTUD2	-309.0
UBC	-323.0
LUC7L3	-407.0
PSMD5	-411.0
TRMT12	-448.0
DNAJC8	-479.0
GTF2H4	-482.0
PPWD1	-493.0
TGS1	-515.0
PSMA5	-534.0
POLR2F	-559.0
DHX35	-560.0
SNRPB2	-562.0
SF3B1	-578.0
TSEN2	-580.0
PPP2R2A	-603.0
UTP14C	-604.0
PRKCD	-615.0
SRSF2	-624.0
HNRNPA2B1	-638.0
RPS27	-651.0
RPL22	-684.0
MAPK14	-685.0
PSMB9	-734.0
PSME4	-771.0
PAPOLA	-775.0
PSMD11	-805.0
PLRG1	-837.0
NSRP1	-839.0
NUP98	-843.0
METTL14	-872.0
EDC4	-892.0
RNGTT	-921.0
TRIT1	-925.0
POLDIP3	-926.0
DDX23	-1004.0
UTP11	-1022.0
IGF2BP1	-1115.0
SRSF1	-1120.0
RPP14	-1175.0
CHTOP	-1176.0
SAP18	-1189.0
TRMT6	-1224.0
DHX38	-1284.0
RPS18	-1287.0
RPS8	-1337.0
NUP205	-1359.0
ERCC2	-1393.0
ETF1	-1431.0
ADAT2	-1449.0
TSR1	-1471.0
GTF2F1	-1517.0
IMP4	-1529.0
DDX47	-1532.0
DDX39A	-1535.0
SUPT5H	-1673.0
SNRNP200	-1738.0
TRMT9B	-1743.0
RPL35	-1762.0
ERCC3	-1766.0
PHAX	-1830.0
DDX6	-1863.0
URM1	-1872.0
PSMD7	-1937.0
PUS3	-1944.0
CPSF1	-1964.0
CCAR1	-1980.0
BUD13	-1982.0
CPSF4	-1983.0
FCF1	-2024.0
RPL32	-2032.0
DDX49	-2034.0
EXOSC3	-2039.0
RTCB	-2043.0
POLR2D	-2050.0
SRRM1	-2077.0
EIF4G1	-2231.0
SNRPD3	-2277.0
RPL18A	-2322.0
NIP7	-2327.0
NUP210	-2340.0
DCAF13	-2351.0
UPF2	-2360.0
SRSF11	-2372.0
WTAP	-2401.0
YWHAB	-2453.0
NOP10	-2457.0
SNRPB	-2463.0
TYW5	-2468.0
PPIE	-2503.0
RPLP0	-2534.0
XRN1	-2628.0
PUS1	-2633.0
QTRT2	-2687.0
CPSF2	-2759.0
LSM2	-2804.0
CDC5L	-2824.0
NSUN6	-2833.0
WDR4	-2857.0
DHX15	-2878.0
PSMD9	-2906.0
RPS25	-2921.0
METTL1	-2934.0
SMG7	-2968.0
PRPF19	-3075.0
BYSL	-3095.0
NOL6	-3101.0
XPOT	-3187.0
RPS6	-3203.0
EXOSC10	-3242.0
RPL22L1	-3364.0
POLR2L	-3453.0
TSR3	-3469.0
SMN1	-3580.5
SMN2	-3580.5
MAPK11	-3633.0
IGF2BP2	-3661.0
HEATR1	-3669.0
SKIC2	-3670.0
DDX39B	-3686.0
GTF2H1	-3725.0
RBM25	-3774.0
RPLP2	-3777.0
SRRM2	-3783.0
RIOK1	-3821.0
TRMT13	-3830.0
GPATCH1	-3858.0
TFB1M	-3876.0
TUT7	-3885.0
CDKAL1	-3914.0
MAGOHB	-3930.0
NOP58	-3959.0
RPL14	-3997.0
SRSF4	-4008.0
DCP1B	-4056.0
METTL3	-4067.0
THG1L	-4075.0
UPF3A	-4154.0
SMG5	-4189.0
RPL12	-4199.0
NHP2	-4228.0
TNKS1BP1	-4286.0
RPL30	-4351.0
RPS15	-4386.0
SART1	-4448.0
PSMC3	-4492.0
NUDT21	-4522.0
NOC4L	-4566.0
RPL31	-4613.0
RNPS1	-4620.0
HNRNPC	-4690.0
FIP1L1	-4704.0
NDC1	-4745.0
DDX42	-4827.0
GTF2F2	-4849.0
WDR36	-4969.0
TRMU	-4976.0
MAGOH	-5021.0
PUF60	-5041.0
ELAVL1	-5083.0
TEX10	-5103.0
NUP42	-5150.0
MRM2	-5209.0
SNRPD1	-5225.0
RANBP2	-5265.0
PSMD14	-5297.0
NUP37	-5314.0
DHX8	-5315.0
THOC5	-5341.0
SRSF9	-5382.0
SMG9	-5384.0
PSMD1	-5508.0
PSMD6	-5633.0
PSMF1	-5638.0
SF3B5	-5674.0
BUD23	-5683.0
NUP93	-5736.0
RNPC3	-5740.0
CNOT1	-5830.0
SMG1	-5849.0
APOBEC3B	-5879.0
PUS7	-5995.0
U2AF2	-6030.0
THOC7	-6081.0
UPF1	-6119.0
EXOSC9	-6121.0
NUP54	-6131.0
CLNS1A	-6219.0
EIF4A2	-6222.0
PRPF3	-6257.0
PRPF6	-6261.0
SMG8	-6358.0
CWC25	-6372.0
RPS26	-6416.0
RRP1	-6480.0
RPS27A	-6484.0
CNOT7	-6586.0
PSMA8	-6587.0
PSMC4	-6643.0
SLU7	-6648.0
SEC13	-6814.0
EIF4A1	-6870.0
APOBEC4	-6896.0
RPL3L	-6960.0
SF3A1	-7011.0
SNU13	-7060.0
ZMAT2	-7103.0
TBL3	-7182.0
PSMA4	-7243.0
ELAC2	-7300.0
PABPC1	-7335.0
CTU2	-7351.0
DDX41	-7366.0
RPL8	-7369.0
PNRC2	-7372.0
RPL23A	-7390.0
RPL5	-7510.0
AQR	-7537.0
RCL1	-7673.0
PTBP1	-7736.0
RPL3	-7876.0
TYW3	-7885.0
LSM7	-7904.0
A1CF	-8061.0
NOP56	-8197.0
RPL10L	-8234.0
TPR	-8306.0
RPL13A	-9002.5
SRRT	-9083.0
RPL7A	-9413.0
PWP2	-9524.0
APOBEC3H	-9542.0
PSMB11	-9711.0
POLR2J	-10431.0

---

REACTOME_CELL_CYCLE_MITOTIC

REACTOME_CELL_CYCLE_MITOTIC

	1112
set	REACTOME_CELL_CYCLE_MITOTIC
setSize	539
pANOVA	1.11e-09
s.dist	0.153
p.adjustANOVA	2.28e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CHMP4C	11134
USO1	10970
CSNK1E	10909
H3-3A	10816
CDKN2D	10796
PPP2R5B	10604
MZT2B	10599
H2AC4	10558
CDC25C	10524
H2BC17	10497
MYBL2	10417
TUBB4B	10395
H4C16	10315
H2BC15	10314
POLE2	10284
CTDNEP1	10173
RAN	10098
H3-3B	10095
H4C3	10086
H2AC6	10052

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CHMP4C	11134.0
USO1	10970.0
CSNK1E	10909.0
H3-3A	10816.0
CDKN2D	10796.0
PPP2R5B	10604.0
MZT2B	10599.0
H2AC4	10558.0
CDC25C	10524.0
H2BC17	10497.0
MYBL2	10417.0
TUBB4B	10395.0
H4C16	10315.0
H2BC15	10314.0
POLE2	10284.0
CTDNEP1	10173.0
RAN	10098.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
PSMD13	10036.0
TUBG1	10027.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
NSL1	9840.0
CDK11A	9802.0
CSNK2A1	9778.0
SGO1	9752.0
H3C12	9726.0
H2BC21	9693.0
ANAPC10	9626.0
PHLDA1	9532.0
KIF20A	9474.0
POM121	9464.0
BIRC5	9463.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
NEK6	9352.0
TUBB6	9322.0
UBE2S	9214.0
TUBG2	9179.0
CCNB1	9175.0
CDKN2B	9139.0
SIRT2	9130.0
MASTL	9071.0
CKS1B	9069.0
CDKN2C	9068.0
H2AZ1	9026.0
H2AC20	9019.0
RAB1B	8943.0
UBB	8935.0
KMT5A	8915.0
E2F5	8896.0
AURKA	8822.0
POLE4	8745.0
CENPC	8675.0
HAUS2	8672.0
PSMA6	8609.0
CDC23	8577.0
PCNA	8551.0
GINS1	8549.0
ZW10	8484.0
TUBA4B	8469.0
CENPH	8445.0
ORC2	8430.0
KPNB1	8399.0
ORC6	8363.0
DYNC1LI2	8336.0
TNPO1	8276.0
POLE3	8257.0
PSMC6	8173.0
CCNH	8147.0
CDC26	8079.0
RAE1	8059.0
CENPS	8051.0
NUP58	8047.0
GINS4	8021.0
TUBA8	8019.0
CEP41	8012.0
KIF23	8000.0
TP53	7995.0
E2F1	7979.0
NUP43	7960.0
POLD4	7923.0
RPA3	7810.0
NUP35	7791.0
PSME3	7776.0
CEP43	7761.0
NUP50	7744.0
BLZF1	7717.0
RPA2	7679.0
H3C4	7677.0
RCC1	7522.0
LIN9	7497.0
TUBB4A	7468.0
PPP2R5A	7419.0
NEDD1	7410.0
UBE2E1	7409.0
TUBA4A	7384.0
H2BC11	7363.0
H2BC5	7354.0
HMMR	7237.0
CHMP2A	7210.0
NCAPG	7209.0
DCTN1	7164.0
NME7	7129.0
RFC4	7122.0
MYC	7102.0
LIN37	7094.0
POLD1	7018.0
CHMP4A	6900.0
ORC1	6899.0
MCPH1	6889.0
DYNLL2	6886.0
H2BC3	6877.0
TUBB3	6871.0
HSP90AB1	6865.0
CEP250	6859.0
CENPA	6857.0
HAUS1	6787.0
CHMP2B	6780.0
PSMB3	6752.0
CDK7	6742.0
GINS2	6674.0
PSMD12	6656.0
NUMA1	6650.0
CDCA8	6641.0
NUP88	6529.0
LYN	6506.0
H4C1	6505.0
PLK4	6498.0
FBXL18	6456.0
DYNC1LI1	6419.0
CENPT	6418.0
AJUBA	6380.0
CENPM	6270.0
MCM2	6216.0
POLD2	6199.0
DBF4	6178.0
CSNK2B	6147.0
ANAPC7	6124.0
PSMB7	6049.0
NUP155	6039.0
RBBP4	6026.0
XPO1	5947.0
SPAST	5932.0
LPIN1	5850.0
H4C2	5849.0
H2AJ	5832.0
H2AX	5821.0
ANAPC2	5784.0
ESCO2	5749.0
RFC5	5739.0
VRK2	5692.0
CHMP7	5637.0
SDCCAG8	5605.0
H4C12	5591.0
ANAPC11	5571.0
LIN52	5471.0
CDK1	5463.0
PSMC1	5452.0
DSN1	5434.0
PPP2R1A	5421.0
FZR1	5395.0
CKAP5	5383.0
H4C8	5375.0
SET	5356.0
TUBB2A	5342.0
TUBA3C	5315.0
ZWILCH	5257.0
VPS4A	5230.0
CDK5RAP2	5227.0
CDK11B	5212.0
PRKCB	5164.0
PSMD8	5087.0
CSNK2A2	4931.0
ANAPC16	4927.0
NDE1	4740.0
KIF18A	4714.0
RAB1A	4671.0
CDKN1B	4666.0
BANF1	4658.0
PPP2R5C	4656.0
PSMB10	4635.0
ENSA	4581.0
DHFR	4551.0
BTRC	4547.0
ORC5	4541.0
TAOK1	4538.0
CDCA5	4511.0
CCND3	4481.0
PSMD3	4433.0
CDC27	4430.0
UBE2C	4394.0
CDKN1A	4380.0
CENPE	4344.0
ORC4	4334.0
DYNC1H1	4333.0
AURKB	4328.0
DYNC1I1	4315.0
H3C6	4303.0
PSMA3	4156.0
CUL1	4104.0
GSK3B	4062.0
H2AZ2	4022.0
RAB2A	4004.0
CABLES1	3994.0
TUBGCP4	3974.0
PSMC2	3840.0
GORASP2	3821.0
B9D2	3791.0
HAUS4	3783.0
PMF1	3768.0
TPX2	3724.0
TUBB	3708.0
MZT2A	3702.0
CEP290	3693.0
DYNC1I2	3671.0
NDC80	3635.0
NUP133	3627.0
ESPL1	3625.0
CLASP1	3593.0
NUP160	3568.0
SRC	3558.0
PCM1	3462.0
RBL2	3425.0
LCMT1	3402.0
CEP152	3343.0
CDC45	3327.0
CEP63	3302.0
FBXW11	3290.0
NUP214	3289.0
SPC24	3282.0
YWHAG	3187.0
CHMP3	3159.0
DCTN2	3142.0
PSMC5	3099.0
HDAC1	3086.0
CEP57	3058.0
CDT1	2997.0
NUP188	2995.0
CLASP2	2994.0
CDK2	2988.0
CEP70	2984.0
DYRK1A	2980.0
UBA52	2963.0
PSMB1	2960.0
SSNA1	2919.0
TYMS	2878.0
PCNT	2859.0
ANAPC4	2830.0
DNA2	2805.0
SKP2	2789.0
LPIN2	2771.0
KNL1	2766.0
CEP76	2739.0
AKAP9	2716.0
H2BC1	2654.0
LBR	2649.0
ABL1	2597.0
PSMB2	2596.0
STAG1	2592.0
H3C10	2553.0
CCNB2	2521.0
MZT1	2513.0
PSMA1	2497.0
PSMB5	2455.0
PSMD2	2443.0
PSMA7	2417.0
PPME1	2396.0
AKT1	2390.0
DYNLL1	2349.0
CCND1	2318.0
SEH1L	2309.0
PLK1	2308.0
SMC4	2289.0
PSMB4	2281.0
PRKCA	2239.0
CDKN1C	2152.0
LIG1	2069.0
PSMD4	2042.0
H2BC10	2021.0
WEE1	2003.0
PPP1CB	1956.0
ODF2	1921.0
GINS3	1900.0
RPA1	1885.0
RAB8A	1869.0
BORA	1864.0
PPP2CA	1855.0
E2F3	1797.0
RFC2	1760.0
LIN54	1733.0
BUB1B	1694.0
MNAT1	1602.0
CENPO	1592.0
KIF2C	1583.0
PSME1	1571.0
MAPRE1	1549.0
SKP1	1543.0
NEK2	1458.0
NUP107	1453.0
NCAPD3	1434.0
PDS5A	1397.0
RB1	1335.0
SMC2	1295.0
PSME2	1245.0
NEK7	1231.0
PSMA2	1218.0
CENPQ	1164.0
PSMB6	1163.0
POM121C	1147.0
E2F6	1123.0
NUP62	1081.0
TUBB1	1042.0
NCAPG2	1015.0
FEN1	994.0
NUP85	973.0
TUBAL3	971.0
POLE	963.0
CNTRL	908.0
MAPK3	901.0
RFC3	822.0
LEMD3	798.0
IST1	783.0
EP300	777.0
CCNA1	745.0
RCC2	742.0
H3C1	733.0
H4C11	725.0
H4C5	654.0
CSNK1D	610.0
UBE2D1	557.0
CDC16	525.0
H2BC12	519.0
MAD1L1	516.0
ACTR1A	495.0
TUBGCP3	441.0
H3C11	416.0
SEM1	329.0
TUBA1B	276.0
CCP110	211.0
PPP1R12A	209.0
AAAS	206.0
H4C4	162.0
PAFAH1B1	139.0
POLA2	56.0
MCM6	47.0
RAD21	23.0
CCND2	11.0
PSMB8	-53.0
PDS5B	-69.0
NUP153	-100.0
TUBGCP2	-185.0
CDC6	-211.0
CEP72	-254.0
MIS12	-257.0
UBC	-323.0
H3C8	-350.0
PPP2R1B	-352.0
ARPP19	-377.0
PSMD5	-411.0
CENPL	-455.0
JAK2	-474.0
KNTC1	-501.0
CDK6	-504.0
AKT3	-509.0
PSMA5	-534.0
ANAPC1	-538.0
ESCO1	-550.0
PPP2R2A	-603.0
MAX	-612.0
RPS27	-651.0
ANKLE2	-687.0
PSMB9	-734.0
PSME4	-771.0
PSMD11	-805.0
RFC1	-815.0
ORC3	-828.0
NUP98	-843.0
CEP131	-860.0
SGO2	-877.0
MCM3	-889.0
CLIP1	-1032.0
PPP2R5E	-1166.0
PTK6	-1231.0
CDKN2A	-1239.0
EML4	-1280.0
MCM4	-1286.0
NDEL1	-1297.0
NUP205	-1359.0
GMNN	-1366.0
HAUS8	-1392.0
ALMS1	-1415.0
FOXM1	-1454.0
SKA2	-1465.0
CENPN	-1557.0
PPP2R5D	-1720.0
HAUS6	-1764.0
MAPK1	-1794.0
NEK9	-1833.0
CDK4	-1880.0
PPP1CC	-1885.0
CDC25B	-1894.0
VRK1	-1901.0
PSMD7	-1937.0
TUBGCP6	-1945.0
E2F2	-2047.0
RBL1	-2049.0
NCAPD2	-2122.0
TFDP1	-2145.0
PTTG1	-2237.0
NUP210	-2340.0
CC2D1B	-2395.0
NUDC	-2458.0
TOP2A	-2478.0
CDC14A	-2512.0
HAUS3	-2539.0
TFDP2	-2551.0
CCNE2	-2648.0
PPP1R12B	-2770.0
NUF2	-2839.0
PSMD9	-2906.0
PRIM2	-2930.0
MCM8	-2989.0
SUMO1	-3031.0
AHCTF1	-3049.0
MCM5	-3052.0
CDC20	-3146.0
MAU2	-3169.0
FBXO5	-3238.0
BUB3	-3248.0
PRKACA	-3280.0
LMNB1	-3282.0
LMNA	-3373.0
PRKAR2B	-3491.0
ANAPC5	-3528.0
ANAPC15	-3556.0
TUBA1A	-3578.0
BUB1	-3658.0
CEP164	-3729.0
H4C6	-3817.0
TUBA3E	-3827.0
PPP2R2D	-3904.0
CEP135	-3908.0
FBXL7	-3947.0
TUBGCP5	-3955.0
HSP90AA1	-4000.0
SKA1	-4015.0
TUBA1C	-4095.0
SPDL1	-4219.0
MAD2L1	-4227.0
KIF2B	-4290.0
ITGB3BP	-4330.0
CCNA2	-4363.0
CHMP4B	-4388.0
PSMC3	-4492.0
H3C3	-4506.0
LPIN3	-4588.0
PPP2CB	-4627.0
YWHAE	-4657.0
NIPBL	-4687.0
MCM7	-4735.0
NDC1	-4745.0
H3-4	-4773.0
RRM2	-4822.0
H2BC26	-4831.0
CENPU	-4840.0
TUBA3D	-4880.0
CEP192	-4953.0
CEP78	-4974.0
SPC25	-4986.0
HAUS5	-5034.0
FKBPL	-5124.0
CDC25A	-5146.0
NUP42	-5150.0
TK1	-5191.0
RANBP2	-5265.0
NINL	-5271.0
PSMD14	-5297.0
NUP37	-5314.0
CENPF	-5361.0
H2AC18	-5415.5
H2AC19	-5415.5
TMPO	-5468.0
PSMD1	-5508.0
PSMD6	-5633.0
CDC7	-5634.0
PSMF1	-5638.0
NCAPH	-5690.0
NUP93	-5736.0
SFI1	-5747.0
RANGAP1	-5823.0
CENPK	-5871.0
CENPP	-5908.0
LEMD2	-6049.0
GOLGA2	-6063.0
H4C13	-6090.0
NUP54	-6131.0
SMC3	-6169.0
WAPL	-6268.0
OPTN	-6314.0
ZWINT	-6341.0
CENPJ	-6375.0
AKT2	-6463.0
RPS27A	-6484.0
PSMA8	-6587.0
PSMC4	-6643.0
SEC13	-6814.0
GORASP1	-6885.0
RBX1	-6897.0
MCM10	-7100.0
POLD3	-7106.0
DCTN3	-7114.0
CNEP1R1	-7168.0
H2BC14	-7223.0
PSMA4	-7243.0
TUBB2B	-7326.0
GTSE1	-7362.0
KIF2A	-7387.0
CHMP6	-7414.0
H2BC13	-7559.0
E2F4	-7591.0
UBE2I	-7598.0
PRIM1	-7751.0
CCNE1	-7855.0
H2AC14	-7938.0
H4C9	-8005.0
TPR	-8306.0
INCENP	-8317.0
NCAPH2	-8346.0
PKMYT1	-8763.0
TUBB8	-8794.0
PSMB11	-9711.0

---

REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

	1082
set	REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE
setSize	125
pANOVA	1.34e-09
s.dist	-0.314
p.adjustANOVA	2.44e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
LCE2B	-10451
SPRR3	-10237
KRT15	-10219
KRT17	-10076
LCE1F	-10016
KRT76	-9936
KRT73	-9926
KRT82	-9873
KRT24	-9855
KRT35	-9819
KRT80	-9794
PI3	-9793
DSG4	-9712
LCE3D	-9696
TGM5	-9666
KRT4	-9591
KRT79	-9536
LIPK	-9475
KRT20	-9394
LCE5A	-9383

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
LCE2B	-10451
SPRR3	-10237
KRT15	-10219
KRT17	-10076
LCE1F	-10016
KRT76	-9936
KRT73	-9926
KRT82	-9873
KRT24	-9855
KRT35	-9819
KRT80	-9794
PI3	-9793
DSG4	-9712
LCE3D	-9696
TGM5	-9666
KRT4	-9591
KRT79	-9536
LIPK	-9475
KRT20	-9394
LCE5A	-9383
KRT23	-9368
KRT26	-9364
LCE1B	-9354
KRT33B	-9260
RPTN	-9250
KRT6A	-9098
KRT6B	-9026
PKP3	-8966
LCE4A	-8876
KRT75	-8853
KLK14	-8847
TGM1	-8766
KRT78	-8694
KRT85	-8651
EVPL	-8563
LELP1	-8514
CDSN	-8228
DSC1	-8150
KRT34	-8059
KRT28	-7854
KRT32	-7834
KRT6C	-7491
DSG1	-7415
PCSK6	-7348
KRT83	-7261
JUP	-7211
KAZN	-7200
IVL	-7050
DSG3	-6846
SPINK5	-6753
LCE2C	-6612
KRT77	-6271
LCE3B	-5860
CELA2A	-5778
KRT33A	-5777
KRT5	-5536
FLG	-5381
KRT39	-5370
SPRR2A	-5202
LIPN	-5182
SPRR1B	-5176
SPRR2F	-5139
SPRR2G	-5098
KLK12	-5091
PKP2	-4810
ST14	-4509
KRT38	-4377
KRT74	-3694
LCE2A	-3624
KRT2	-3510
KRT71	-2998
KRT9	-2972
CASP14	-2695
KRT36	-2364
KRT27	-2264
SPRR1A	-2221
SPRR2D	-2054
LCE3E	-1888
KRT25	-1864
KRT81	-1780
KRT7	-1194
KRT86	-1145
FURIN	-1134
PKP4	-709
LCE1A	-487
KRT12	-403
KRT13	-293
PPL	555
SPINK9	559
KRT18	1002
KLK8	1270
KRT10	1640
KRT8	1818
KRT31	2030
KRT3	2044
TCHH	2220
KRT14	2464
LCE1C	2554
DSC2	2686
KRT84	3103
PKP1	3395
KLK5	3597
DSG2	4366
SPINK6	4699
KRT72	5076
KRT40	5190
CAPN1	5593
KRT37	6385
CSTA	6499
LCE6A	6510
DSP	6839
LCE2D	6880
PERP	6942
LCE1E	7013
CAPNS1	7220
PRSS8	7375
KRT19	7958
KLK13	9610
DSC3	9650
KRT1	9728
KRT16	10020
LIPM	10250
SPRR2E	10444
LIPJ	10763
LCE3A	11232

---

REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

	115
set	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX
setSize	134
pANOVA	3.08e-09
s.dist	-0.296
p.adjustANOVA	5.05e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CTRB2	-10414
KLKB1	-10008
PRSS1	-9986
CAPNS2	-9965
CAPN13	-9674
CTSG	-9290
CTRB1	-9220
MMP7	-8911
COL5A1	-8421
COL13A1	-8413
CAPN8	-8403
COL6A6	-8274
COL5A2	-8166
MMP20	-7932
MMP3	-7908
KLK2	-7836
COL6A2	-7817
MMP1	-7694
ADAMTS4	-7693
CTSS	-7691

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CTRB2	-10414
KLKB1	-10008
PRSS1	-9986
CAPNS2	-9965
CAPN13	-9674
CTSG	-9290
CTRB1	-9220
MMP7	-8911
COL5A1	-8421
COL13A1	-8413
CAPN8	-8403
COL6A6	-8274
COL5A2	-8166
MMP20	-7932
MMP3	-7908
KLK2	-7836
COL6A2	-7817
MMP1	-7694
ADAMTS4	-7693
CTSS	-7691
COL7A1	-7631
COL4A4	-7607
MMP15	-7589
COL11A2	-7540
COL6A5	-7445
MMP19	-7378
COL17A1	-7374
ELN	-7359
CMA1	-7206
MMP12	-7170
A2M	-7047
CAPN14	-6975
HSPG2	-6970
COL4A2	-6813
MMP8	-6780
MMP16	-6708
ELANE	-6486
FN1	-6453
COL23A1	-6393
LAMC1	-6158
DCN	-6098
CAPN15	-6097
CAPN3	-5962
LAMB1	-5957
SPOCK3	-5821
COL3A1	-5646
COL18A1	-5630
SCUBE1	-5487
TLL2	-5477
ADAM9	-5469
CAPN10	-5405
MMP2	-5346
CAPN12	-4945
LAMC2	-4757
MMP17	-4551
ADAMTS16	-4477
LAMA5	-4204
FBN1	-4132
COL5A3	-4044
MMP13	-4021
BSG	-3999
COL4A1	-3939
ADAM10	-3906
ADAM8	-3840
COL6A1	-3677
CAPN5	-3672
COL16A1	-3559
FBN3	-3449
BMP1	-3446
ADAMTS5	-3348
COL8A1	-3145
COL6A3	-3117
COL26A1	-3055
TMPRSS6	-2954
TIMP2	-2940
LAMB3	-2922
COL14A1	-2593
NID1	-2590
COL25A1	-2566
TLL1	-2535
NCSTN	-2474
MMP14	-2346
MMP9	-2279
ACAN	-2046
ADAMTS18	-1971
FBN2	-1927
CTSB	-1891
COL4A3	-1751
COL12A1	-1678
ADAMTS1	-1669
CAPN9	-1619
COL1A2	-1423
COL10A1	-1268
FURIN	-1134
CDH1	-945
COL15A1	-923
LAMA3	-375
ADAMTS9	-357
SCUBE3	-268
PLG	-186
COL1A1	412
CD44	779
PHYKPL	842
OPTC	851
COL19A1	1022
MMP25	1046
COL9A1	1187
COL8A2	1342
COL11A1	1634
ADAM17	1830
CAPN2	2193
HTRA1	2777
MMP11	2982
MMP24	3278
CASP3	3662
COL2A1	3703
COL9A2	3989
CTSD	4081
PSEN1	4110
CAPN7	4133
CAST	4895
CAPN11	4941
CTSK	5006
MMP10	5121
CAPN1	5593
ADAM15	5771
CAPNS1	7220
COL9A3	7370
ADAMTS8	7572
KLK7	7885
CTSV	8307
BCAN	8702
SPP1	9241
CTSL	10003

---

REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

	116
set	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION
setSize	291
pANOVA	3.63e-09
s.dist	-0.201
p.adjustANOVA	5.42e-07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CTRB2	-10414
KLKB1	-10008
PRSS1	-9986
CAPNS2	-9965
FGG	-9928
CAPN13	-9674
DSPP	-9671
ADAMTS14	-9585
COL27A1	-9463
VCAM1	-9458
CTSG	-9290
COL28A1	-9261
CTRB1	-9220
FGA	-9164
FBLN1	-9146
MFAP2	-9130
TTR	-9047
MMP7	-8911
ITGB6	-8907
LTBP2	-8826

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CTRB2	-10414
KLKB1	-10008
PRSS1	-9986
CAPNS2	-9965
FGG	-9928
CAPN13	-9674
DSPP	-9671
ADAMTS14	-9585
COL27A1	-9463
VCAM1	-9458
CTSG	-9290
COL28A1	-9261
CTRB1	-9220
FGA	-9164
FBLN1	-9146
MFAP2	-9130
TTR	-9047
MMP7	-8911
ITGB6	-8907
LTBP2	-8826
MFAP5	-8784
ITGA10	-8700
SDC1	-8515
ITGA11	-8513
TNR	-8491
ASPN	-8444
COL5A1	-8421
COL13A1	-8413
CAPN8	-8403
P3H3	-8348
COL6A6	-8274
COL5A2	-8166
AGRN	-8013
MMP20	-7932
TGFB3	-7924
MMP3	-7908
KLK2	-7836
COL6A2	-7817
DMP1	-7719
MMP1	-7694
ADAMTS4	-7693
CTSS	-7691
COL7A1	-7631
ITGA3	-7618
COL4A4	-7607
MMP15	-7589
LOXL2	-7577
COL11A2	-7540
FBLN2	-7528
IBSP	-7466
COL6A5	-7445
LUM	-7421
MMP19	-7378
COL17A1	-7374
ELN	-7359
DDR2	-7322
ADAMTS2	-7308
LAMA1	-7232
CMA1	-7206
MMP12	-7170
ITGB5	-7109
A2M	-7047
P3H2	-7040
CAPN14	-6975
HSPG2	-6970
TNC	-6945
HAPLN1	-6919
COL4A2	-6813
MMP8	-6780
MMP16	-6708
MUSK	-6640
LOXL4	-6551
ELANE	-6486
TNN	-6478
VWF	-6464
FN1	-6453
COL23A1	-6393
ITGA2B	-6213
ITGA7	-6168
LAMC1	-6158
DCN	-6098
CAPN15	-6097
MATN4	-6045
CAPN3	-5962
LAMB1	-5957
ITGAL	-5932
NCAM1	-5882
ITGAD	-5872
SPOCK3	-5821
PLOD2	-5706
JAM3	-5691
COL3A1	-5646
COL18A1	-5630
SCUBE1	-5487
TLL2	-5477
ADAM9	-5469
CAPN10	-5405
MMP2	-5346
NTN4	-5245
COL20A1	-5164
ITGB3	-4961
CAPN12	-4945
DST	-4764
LAMC2	-4757
P4HA1	-4708
MMP17	-4551
SERPINH1	-4545
LAMA2	-4505
ADAMTS16	-4477
ADAM12	-4451
PTPRS	-4437
LAMB2	-4434
ITGAX	-4397
TNXB	-4310
LAMA5	-4204
MATN1	-4143
FBN1	-4132
PXDN	-4113
COL5A3	-4044
MMP13	-4021
BSG	-3999
PDGFA	-3982
ITGB4	-3971
COL4A1	-3939
ADAM10	-3906
ADAM8	-3840
ITGA9	-3772
COL6A1	-3677
CAPN5	-3672
PCOLCE2	-3620
COL22A1	-3566
COL16A1	-3559
KDR	-3513
FBN3	-3449
BMP1	-3446
ADAM19	-3413
ADAMTS5	-3348
COL21A1	-3345
P4HA3	-3252
COL8A1	-3145
COL6A3	-3117
COL26A1	-3055
BMP7	-2983
TMPRSS6	-2954
TIMP2	-2940
LAMB3	-2922
ITGA8	-2756
ADAMTS3	-2693
COL14A1	-2593
NID1	-2590
COL25A1	-2566
TLL1	-2535
NCSTN	-2474
MMP14	-2346
MMP9	-2279
CD151	-2081
PECAM1	-2072
ACAN	-2046
SDC2	-2040
BMP10	-2001
ADAMTS18	-1971
FBN2	-1927
CTSB	-1891
LTBP1	-1831
LAMC3	-1761
COL4A3	-1751
COL12A1	-1678
CD47	-1677
ADAMTS1	-1669
CAPN9	-1619
COL1A2	-1423
TGFB1	-1410
JAM2	-1395
EFEMP1	-1376
NRXN1	-1340
PLOD3	-1319
COL10A1	-1268
LAMA4	-1149
FURIN	-1134
CDH1	-945
COL15A1	-923
P4HA2	-906
SH3PXD2A	-692
ACTN1	-671
P3H1	-392
LAMA3	-375
ADAMTS9	-357
COLGALT2	-320
SCUBE3	-268
TRAPPC4	-249
ITGB1	-205
PLG	-186
ITGA1	-157
DAG1	-41
COL24A1	-7
ITGB8	89
VCAN	275
LOXL3	307
COL1A1	412
ITGA2	548
CD44	779
PHYKPL	842
OPTC	851
ITGAM	910
FMOD	1008
COL19A1	1022
MMP25	1046
LOXL1	1091
COL9A1	1187
COL8A2	1342
ITGAV	1426
COL11A1	1634
CEACAM8	1700
ICAM2	1745
ADAM17	1830
THBS1	2088
CAPN2	2193
PRKCA	2239
HTRA1	2777
MMP11	2982
COLGALT1	3158
MMP24	3278
ITGAE	3431
LOX	3501
CASP3	3662
SERPINE1	3685
COL2A1	3703
NID2	3887
COL9A2	3989
SPARC	4037
CTSD	4081
PSEN1	4110
CAPN7	4133
ITGA4	4351
APP	4531
FGB	4682
PPIB	4706
PLEC	4735
CAST	4895
CAPN11	4941
TGFB2	4960
CTSK	5006
LRP4	5025
MMP10	5121
LTBP4	5126
PLOD1	5181
MATN3	5285
SDC4	5314
SDC3	5389
CEACAM6	5505
CAPN1	5593
FGF2	5690
ADAM15	5771
PCOLCE	5794
EMILIN1	6102
VTN	6308
EMILIN2	6447
F11R	6627
EMILIN3	6829
NCAN	6883
CAPNS1	7220
ICAM3	7343
COL9A3	7370
ICAM4	7454
ADAMTS8	7572
KLK7	7885
COMP	7954
FBLN5	7976
ICAM1	8008
CTSV	8307
ITGB2	8550
ITGB7	8598
BCAN	8702
ITGA5	8800
CRTAP	8820
DDR1	9102
P4HB	9206
SPP1	9241
BMP2	9379
MFAP3	9450
MADCAM1	9468
GDF5	9619
LTBP3	9810
CEACAM1	9887
EFEMP2	9907
CTSL	10003
BMP4	10182
ITGA6	10516
PDGFB	10614
ICAM5	10665
MFAP4	10931

---

REACTOME_INFECTIOUS_DISEASE

REACTOME_INFECTIOUS_DISEASE

	974
set	REACTOME_INFECTIOUS_DISEASE
setSize	910
pANOVA	7.81e-09
s.dist	0.113
p.adjustANOVA	1.07e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CD79A	11420
TAF7	11408
CRB3	11386
PYCARD	11328
LCK	11223
IL10	11214
CHMP4C	11134
IFNA5	11098
GEMIN2	11012
FGR	10921
VAMP2	10831
ATP1B2	10803
H2AC21	10743
IFNGR2	10712
STX1A	10693
ELOC	10605
H2AC4	10558
IFNA21	10547
H2BC17	10497
GNG11	10484

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CD79A	11420.0
TAF7	11408.0
CRB3	11386.0
PYCARD	11328.0
LCK	11223.0
IL10	11214.0
CHMP4C	11134.0
IFNA5	11098.0
GEMIN2	11012.0
FGR	10921.0
VAMP2	10831.0
ATP1B2	10803.0
H2AC21	10743.0
IFNGR2	10712.0
STX1A	10693.0
ELOC	10605.0
H2AC4	10558.0
IFNA21	10547.0
H2BC17	10497.0
GNG11	10484.0
RPL26	10476.0
SFPQ	10465.0
FXYD7	10431.0
HLA-B	10426.0
TXN	10424.0
ELOB	10398.0
TUBB4B	10395.0
H2AC15	10342.0
RNF135	10325.0
H4C16	10315.0
H2BC15	10314.0
RPL10A	10291.0
CD247	10245.0
CBL	10238.0
RAB7A	10227.0
RPS16	10188.0
RAN	10098.0
SYT2	10092.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
PSMD13	10036.0
CTSL	10003.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
ACTG1	9958.0
H2AC16	9919.0
H2AC8	9917.0
BECN1	9905.0
MAP2K6	9884.0
ARPC1B	9820.0
RPL39L	9799.0
ST6GAL1	9798.0
MGAT2	9794.5
RPL36AL	9794.5
JAK3	9762.0
RPL29	9738.0
H3C12	9726.0
PRKACB	9713.0
H2BC21	9693.0
TRIM28	9567.0
SUPT4H1	9529.0
GNAI2	9524.0
PPIH	9512.0
ANO8	9470.0
POM121	9464.0
H2BC8	9455.0
AP1S3	9436.0
H2AC7	9407.5
H2BC7	9407.5
MOGS	9362.0
POLR2C	9358.0
STAT1	9354.0
TUBB6	9322.0
RHBDF2	9303.0
B2M	9299.0
IL6R	9288.0
ISCU	9238.0
VPS18	9156.0
XRCC6	9095.0
PRKAR1A	9090.0
CALR	9075.0
PARP14	9040.0
CYSLTR2	9021.0
H2AC20	9019.0
CNBP	8945.0
UBB	8935.0
JUN	8891.0
RAC1	8876.0
RPL27	8846.0
MYO1C	8817.0
BRK1	8788.0
RPS28	8785.0
SNRPD2	8773.0
GNG13	8769.0
IRAK2	8760.0
KPNA3	8754.0
GNG8	8674.0
PLK2	8667.0
PARP4	8656.0
VPS37B	8630.0
PSMA6	8609.0
ADORA2B	8573.0
REST	8553.0
HLA-E	8552.0
POLR2G	8490.0
TUBA4B	8469.0
DDX5	8460.0
TXNIP	8447.0
SAP30L	8446.0
GALNT1	8440.0
RPL37A	8438.0
RPL26L1	8414.0
TLR9	8402.0
KPNB1	8399.0
HLA-F	8377.0
H2AC11	8376.0
DYNC1LI2	8336.0
TLR2	8292.0
RIPK3	8287.0
H2AC12	8285.0
UBAP1	8258.0
H2AC17	8217.0
CCNK	8203.0
RPS19	8176.0
PSMC6	8173.0
VTA1	8166.0
SNRPF	8155.0
IMPDH1	8149.0
CCNH	8147.0
ZBP1	8126.0
ATP1B3	8075.0
UBE2N	8070.0
RAE1	8059.0
NUP58	8047.0
GJA1	8038.0
TUBA8	8019.0
SUPT16H	8002.0
RPL15	7977.0
NUP43	7960.0
SIGMAR1	7946.0
RPL6	7932.0
PARP16	7901.0
PTPN11	7860.0
NUP35	7791.0
RPL34	7790.0
PSME3	7776.0
IL6	7762.0
NUP50	7744.0
P2RX7	7737.0
H3C4	7677.0
GNB4	7676.0
IFIH1	7675.0
DPEP2	7637.0
ARPC3	7636.0
DAXX	7619.0
RPS3A	7611.0
HSPA1A	7602.0
RPS27L	7580.0
RCC1	7522.0
GATAD2B	7509.0
WIPF2	7499.0
ANO9	7494.0
TUBB4A	7468.0
CHD3	7459.0
MGAT1	7448.0
TUBA4A	7384.0
RPL23	7379.0
H2BC11	7363.0
H2BC5	7354.0
ELMO1	7336.0
RPL35A	7327.0
VEGFA	7320.0
GEMIN5	7284.0
PARP9	7255.0
CHMP2A	7210.0
RPL28	7186.0
GTF2A1	7167.0
VPS37D	7155.0
NFKBIA	7150.0
TAF5	7067.0
ACTR2	7050.0
WIPF1	7048.0
RPL11	7034.0
CCNT2	6992.0
SAR1B	6986.0
CHMP4A	6900.0
DYNLL2	6886.0
GANAB	6885.0
H2BC3	6877.0
TUBB3	6871.0
HSP90AB1	6865.0
VPS33B	6822.0
BRMS1	6820.0
DVL2	6814.0
ATP1A1	6807.0
RPS15A	6793.0
CHMP2B	6780.0
PSMB3	6752.0
CDK7	6742.0
HNRNPA1	6725.0
FKBP4	6681.0
HBEGF	6659.0
IRF3	6657.0
PSMD12	6656.0
CORO1A	6642.0
ACTR3	6639.0
CANX	6634.0
MGAT4B	6626.0
IFNAR1	6604.0
YWHAQ	6594.0
RPL41	6591.0
ADCY8	6576.0
RPLP1	6550.0
RPN1	6549.0
FCGR2A	6539.0
NUP88	6529.0
LYN	6506.0
H4C1	6505.0
FAU	6502.0
MAN2A1	6450.0
DYNC1LI1	6419.0
AP1M1	6413.0
CDC42	6406.0
HLA-A	6401.0
RPL24	6382.0
NCKAP1	6350.0
ABI1	6343.0
GSK3A	6340.0
CCNT1	6333.0
ITPR2	6297.0
SEC23A	6281.0
RPS5	6275.0
SSRP1	6269.0
CD8B	6262.0
DAD1	6163.0
CLTA	6146.0
GUCY2C	6111.0
PSMB7	6049.0
NUP155	6039.0
IL17RC	6038.0
SNRPG	6029.0
RBBP4	6026.0
SEC24A	6013.0
WNT5A	6005.0
XPO1	5947.0
EEF1A1	5887.0
POLR2I	5881.0
MGAT5	5880.0
H4C2	5849.0
HDAC2	5842.0
TAB1	5840.0
NLRP12	5835.0
RPL7	5777.0
PDPK1	5751.0
HAVCR1	5710.0
GATAD2A	5679.0
CHMP7	5637.0
ARID4A	5619.0
H4C12	5591.0
ARPC2	5588.0
STX1B	5562.0
STAM2	5561.0
CDK9	5514.0
RPS29	5507.0
YWHAH	5488.0
PSMC1	5452.0
PACS1	5435.0
MAP2K1	5428.0
RPL36	5403.0
SDC3	5389.0
H4C8	5375.0
ADCY7	5350.0
TUBB2A	5342.0
RPS11	5323.0
TUBA3C	5315.0
SDC4	5314.0
P2RX4	5305.0
HLA-G	5246.0
NFKB1	5242.0
CD79B	5231.0
VPS4A	5230.0
SEC24B	5187.0
MYH9	5185.0
ZDHHC2	5173.0
CUL3	5141.0
TAF12	5134.0
HMOX1	5129.0
GNB5	5118.0
PSMD8	5087.0
VPS36	5082.0
ARPC5	5050.0
GTF2H5	5045.0
RPS20	4993.0
RPS10	4983.0
DUSP16	4979.0
KPNA5	4944.0
RPS9	4917.0
RPL37	4854.0
RPL27A	4853.0
NT5E	4819.0
TAF9	4813.0
AP2A1	4785.0
AP2B1	4781.0
MAP1LC3B	4764.0
NOD1	4737.0
MYO9B	4717.0
PPIB	4706.0
ADCY4	4688.0
GNG7	4681.0
NPM1	4661.0
BANF1	4658.0
PSMB10	4635.0
SUDS3	4594.0
NLRP3	4550.0
BTRC	4547.0
CALM1	4537.0
APP	4531.0
NELFB	4523.0
PRKCSH	4507.0
LTF	4485.0
TAF15	4480.0
ST6GALNAC4	4445.0
PSMD3	4433.0
HNRNPK	4410.0
ZDHHC3	4409.0
ITGA4	4351.0
RPL18	4341.0
TCEA1	4339.0
DYNC1H1	4333.0
EIF2AK2	4324.0
DYNC1I1	4315.0
RPS23	4307.0
H3C6	4303.0
AP2S1	4300.0
AP1M2	4299.0
IFNB1	4295.0
VPS45	4291.0
PRMT1	4277.0
UBE2V1	4269.0
GTF2E2	4262.0
GPS2	4260.0
TKFC	4238.0
MTA3	4233.0
STT3A	4206.0
RPL9	4204.0
CRBN	4185.0
DDOST	4181.0
DDX20	4163.0
UVRAG	4160.0
PSMA3	4156.0
PRKAR2A	4125.0
RCAN3	4106.0
GSK3B	4062.0
TRIM4	4018.0
WASF2	4008.0
TXNRD1	3982.0
ITPR1	3976.0
NCBP1	3972.0
GEMIN6	3957.0
RPS21	3934.0
KPNA4	3914.0
TAF4B	3873.0
PSMC2	3840.0
CHMP5	3793.0
MGAT4A	3785.0
MAPK8	3772.0
PCBP2	3760.0
PPIG	3716.0
TUBB	3708.0
SERPINE1	3685.0
DYNC1I2	3671.0
YWHAZ	3670.0
TAF6	3656.0
NUP133	3627.0
FZD7	3617.0
RPS12	3607.0
NUP160	3568.0
SRC	3558.0
WIPF3	3551.0
GNAI3	3539.0
IL17RA	3519.0
MAP3K7	3513.0
RPL17	3492.0
TUFM	3479.0
VCP	3474.0
MEFV	3453.0
PSIP1	3448.0
GOLGA7	3417.0
POLR2K	3416.0
HMG20B	3384.0
ROCK1	3379.0
ARID4B	3360.0
DNAJC3	3357.0
NCOR2	3299.0
NUP214	3289.0
KEAP1	3287.0
PALS1	3273.0
YWHAG	3187.0
WASF1	3176.0
TSG101	3166.0
CHMP3	3159.0
RUNX1	3122.0
PSMC5	3099.0
GSDMD	3089.0
HDAC1	3086.0
MTA2	3044.0
IKBKE	3039.0
NUP188	2995.0
VAV1	2979.0
PABPN1	2964.0
UBA52	2963.0
PSMB1	2960.0
RPL13	2937.0
ANO6	2931.0
VAV3	2908.0
ISG15	2875.0
COMT	2868.0
GRB2	2858.0
VPS37C	2839.0
RPSA	2801.0
POLR2B	2795.0
NCK1	2788.0
H2BC1	2654.0
IFNAR2	2650.0
FXYD2	2612.0
ABL1	2597.0
PSMB2	2596.0
CREBBP	2578.0
H3C10	2553.0
PSMA1	2497.0
GRSF1	2470.0
PSMB5	2455.0
PSMD2	2443.0
PSMA7	2417.0
WASL	2415.0
PDCD6IP	2394.0
AKT1	2390.0
TRAF3	2359.0
DYNLL1	2349.0
KPNA2	2347.0
ADCY9	2330.0
NELFCD	2322.0
SEH1L	2309.0
PSMB4	2281.0
RNMT	2264.0
ZDHHC20	2234.0
CYBA	2203.0
STING1	2170.0
GNG4	2154.0
SLC25A4	2140.0
SV2B	2134.0
LIG1	2069.0
PSMD4	2042.0
CRK	2025.0
H2BC10	2021.0
MVB12B	1947.0
TBL1XR1	1940.0
CD9	1939.0
RPL38	1935.0
PIK3R4	1925.0
RPL19	1906.0
SAP30	1886.0
ELMO2	1880.0
GNG5	1875.0
ADAM17	1830.0
CLTC	1791.0
GTF2H3	1736.0
NELFE	1662.0
CAV1	1619.0
VPS16	1603.0
MNAT1	1602.0
ELL	1591.0
PSME1	1571.0
SKP1	1543.0
ACTB	1540.0
GNG10	1521.0
IL18	1511.0
POLR2A	1481.0
NUP107	1453.0
SUGT1	1427.0
ST3GAL1	1412.0
GNAS	1357.0
RB1	1335.0
GNGT2	1322.0
RPS7	1305.0
RPS2	1277.0
NFE2L2	1267.0
SFN	1261.0
SRPK1	1255.0
PSME2	1245.0
PSMA2	1218.0
ZCRB1	1202.0
PSMB6	1163.0
SMAD3	1155.0
POM121C	1147.0
CHD4	1146.0
JAK1	1127.0
ENO1	1100.0
TRAF6	1095.0
NUP62	1081.0
GTF2B	1075.0
SP1	1043.0
TUBB1	1042.0
TLR1	1019.0
PARP10	1012.0
ANO3	1010.0
FEN1	994.0
NMT2	974.0
NUP85	973.0
TUBAL3	971.0
SNRPE	966.0
AP1S1	957.0
RPS14	948.0
MAPK3	901.0
FNTA	893.0
ANO5	873.0
AP1G1	827.0
IL1B	815.0
EP300	777.0
PATJ	757.0
H3C1	733.0
PML	732.0
NFKB2	730.0
EDEM2	729.0
H4C11	725.0
TAF3	666.0
MVB12A	657.0
H4C5	654.0
RPS24	630.0
AHCYL1	629.0
GEMIN7	612.0
GEMIN4	573.0
RELA	572.0
RPS13	553.0
H2BC12	519.0
POLR2E	455.0
NCBP2	442.0
ENTPD1	431.0
SYK	418.0
H3C11	416.0
NR3C1	406.0
SEC24D	369.0
POLR2H	334.0
SEM1	329.0
TAF10	308.0
IFNGR1	281.0
TUBA1B	276.0
BRD4	263.0
EZH2	243.0
VAMP1	228.0
AAAS	206.0
CBX1	200.0
SMAD4	194.0
CBLL1	185.0
H4C4	162.0
GNAI1	128.0
ARPC4	115.0
RCOR1	102.0
RPL21	76.0
NMI	72.0
RPS3	69.0
ROCK2	64.0
MGAT4C	28.0
MAP2K3	0.0
PSMB8	-53.0
FXYD6	-62.0
NUP153	-100.0
STAT2	-123.0
RPL4	-172.0
SV2A	-192.0
PLCG2	-204.0
ITGB1	-205.0
NMT1	-235.0
ATP6V1H	-262.0
ITPR3	-266.0
FNTB	-306.0
CREB1	-314.0
ELOA2	-319.0
UBC	-323.0
VHL	-326.0
H3C8	-350.0
GNB1	-354.0
XRCC4	-355.0
CXCR4	-370.0
PSMD5	-411.0
JAK2	-474.0
GTF2H4	-482.0
AKT3	-509.0
PSMA5	-534.0
POLR2F	-559.0
CUL5	-608.0
HCK	-635.0
ST3GAL3	-645.0
RPS27	-651.0
BAIAP2	-664.0
SEC24C	-674.0
RPL22	-684.0
MAPK14	-685.0
PSMB9	-734.0
SV2C	-756.0
PSME4	-771.0
FKBP1A	-804.0
PSMD11	-805.0
NUP98	-843.0
PARP1	-847.0
SOS1	-853.0
TAF2	-880.0
RNGTT	-921.0
S1PR1	-928.0
BLNK	-929.0
CDH1	-945.0
G3BP1	-1008.0
TYK2	-1083.0
NOXA1	-1106.0
FURIN	-1134.0
ATG14	-1169.0
PHF21A	-1187.0
SAP18	-1189.0
MAVS	-1222.0
NOS2	-1243.0
PLCG1	-1251.0
RPS18	-1287.0
EED	-1311.0
ST6GALNAC2	-1315.0
ADCY2	-1325.0
RPS8	-1337.0
PPIA	-1344.0
NUP205	-1359.0
ERCC2	-1393.0
TGFB1	-1410.0
GNG2	-1458.0
SH3GL1	-1460.0
TBP	-1504.0
GTF2F1	-1517.0
TRIM27	-1534.0
NRP1	-1567.0
HDAC3	-1583.0
CTNND1	-1605.0
TJP1	-1608.0
SUPT5H	-1673.0
H2AC1	-1730.0
RPL35	-1762.0
ERCC3	-1766.0
RPN2	-1767.0
KDM1A	-1770.0
ENTPD5	-1778.0
MAPK1	-1794.0
MYO5A	-1795.0
MYO10	-1810.0
GTF2E1	-1829.0
PSMD7	-1937.0
AP2M1	-1978.0
CPSF4	-1983.0
TMPRSS2	-2023.0
RPL32	-2032.0
SDC2	-2040.0
AP2A2	-2041.0
POLR2D	-2050.0
TAB2	-2055.0
GPC1	-2085.0
MAP2K2	-2111.0
CTDP1	-2116.0
ABI2	-2148.0
SYT1	-2186.0
H2AC13	-2215.0
SFTPD	-2222.0
DVL1	-2230.0
ST3GAL2	-2247.0
MAN1B1	-2256.0
SNRPD3	-2277.0
VPS25	-2297.0
RPL18A	-2322.0
AP1B1	-2324.0
NUP210	-2340.0
YWHAB	-2453.0
ANO4	-2460.0
SNRPB	-2463.0
TRIM25	-2471.0
RPLP0	-2534.0
HLA-C	-2543.0
VPS41	-2555.0
HMGA1	-2614.0
IMPDH2	-2751.0
CD163	-2761.0
VPS4B	-2773.0
VPS33A	-2811.0
BCL2L1	-2831.0
PSMD9	-2906.0
RPS25	-2921.0
IKBKB	-2956.0
TOMM70	-3021.0
SUMO1	-3031.0
EPS15	-3044.0
ITCH	-3047.0
FXYD1	-3063.0
PKLR	-3126.0
RPS6	-3203.0
PIK3C3	-3214.0
PRKACA	-3280.0
ANTXR2	-3289.0
GPC5	-3299.0
RAB5A	-3349.0
VPS28	-3361.0
RPL22L1	-3364.0
CSNK1A1	-3398.0
MAP2K7	-3436.0
POLR2L	-3453.0
PRKAR2B	-3491.0
MAP2K4	-3501.0
IPO5	-3503.0
ARPC1A	-3530.0
VAV2	-3550.0
GTF2A2	-3567.0
TUBA1A	-3578.0
SMN1	-3580.5
SMN2	-3580.5
PTGES3	-3640.0
GTF2H1	-3725.0
NELFA	-3739.0
NCKIPSD	-3742.0
RPLP2	-3777.0
LARP1	-3798.0
H4C6	-3817.0
TUBA3E	-3827.0
CYFIP2	-3842.0
NCOR1	-3868.0
SH3GL2	-3909.0
CHMP1A	-3954.0
ELOA	-3967.0
ANTXR1	-3973.0
PRKAR1B	-3974.0
RPL14	-3997.0
HSP90AA1	-4000.0
ZDHHC5	-4007.0
VPS11	-4091.0
TUBA1C	-4095.0
KPNA7	-4112.0
KPNA1	-4128.0
XRCC5	-4164.0
ANO2	-4191.0
RPL12	-4199.0
MET	-4322.0
RPL30	-4351.0
TAF13	-4372.0
GPC2	-4376.0
MBD3	-4382.0
RPS15	-4386.0
CHMP4B	-4388.0
GNB2	-4487.0
PSMC3	-4492.0
H3C3	-4506.0
GNG3	-4514.0
FYN	-4554.0
RPL31	-4613.0
PARP8	-4653.0
YWHAE	-4657.0
C3	-4674.0
SRPK2	-4678.0
NDC1	-4745.0
SNF8	-4748.0
H2BC26	-4831.0
NOD2	-4838.0
GTF2F2	-4849.0
TUBA3D	-4880.0
VPS39	-4885.0
SUZ12	-4896.0
STAM	-4909.0
NCKAP1L	-4932.0
GPC6	-5079.0
ST3GAL4	-5084.0
NUP42	-5150.0
GNAT3	-5199.0
SNRPD1	-5225.0
H2AC25	-5226.0
GNGT1	-5244.0
G3BP2	-5246.0
RANBP2	-5265.0
PSMD14	-5297.0
GNG12	-5298.0
CTNNB1	-5304.0
NUP37	-5314.0
CHUK	-5332.0
EGFR	-5365.0
RIGI	-5371.0
ZDHHC8	-5403.0
H2AC18	-5415.5
H2AC19	-5415.5
IRF7	-5429.0
RIPK2	-5497.0
IFNA14	-5500.0
PSMD1	-5508.0
ST6GALNAC3	-5531.0
ATP1B1	-5597.0
YES1	-5604.0
PTPN6	-5631.0
PSMD6	-5633.0
PSMF1	-5638.0
ADCY6	-5669.0
C3AR1	-5671.0
NUP93	-5736.0
RANGAP1	-5823.0
PSTPIP1	-5881.0
TAF11	-6014.0
TAF1L	-6023.0
FUT8	-6062.0
H4C13	-6090.0
NUP54	-6131.0
IL17F	-6159.0
RIPK1	-6194.0
MTA1	-6195.0
TUSC3	-6198.0
ANO1	-6204.0
ANO7	-6270.0
NOXO1	-6357.0
RPS26	-6416.0
ATP1A4	-6446.0
AKT2	-6463.0
NEDD4L	-6474.0
RPS27A	-6484.0
DOCK1	-6494.0
SIKE1	-6518.0
VPS37A	-6533.0
SNAP25	-6543.0
RANBP1	-6552.0
ATP1A3	-6566.0
ADCY1	-6574.0
PSMA8	-6587.0
PSMC4	-6643.0
TAF4	-6750.0
CEBPD	-6765.0
PDCD1	-6766.0
SEC13	-6814.0
CYFIP1	-6827.0
IL1R1	-6883.0
RBX1	-6897.0
RPL3L	-6960.0
HSPG2	-6970.0
GGT1	-7031.0
ANO10	-7048.0
RNF213	-7077.0
ADCY3	-7084.0
PAK2	-7196.0
H2BC14	-7223.0
PSMA4	-7243.0
PRKACG	-7244.0
BST2	-7263.0
TBK1	-7283.0
TUBB2B	-7326.0
RPL8	-7369.0
RPL23A	-7390.0
CHMP6	-7414.0
MYH2	-7424.0
DOCK2	-7436.0
WASF3	-7469.0
MASP2	-7477.0
ATP1A2	-7488.0
RPL5	-7510.0
H2BC13	-7559.0
PTK2	-7586.0
UBE2I	-7598.0
SH3GL3	-7634.0
DPEP3	-7718.0
HGS	-7732.0
LIG4	-7738.0
ARF1	-7806.0
RPL3	-7876.0
H2AC14	-7938.0
DVL3	-8004.0
H4C9	-8005.0
AGRN	-8013.0
MASP1	-8054.0
FXYD3	-8089.0
GGT5	-8126.0
EEF2	-8152.0
RPL10L	-8234.0
IFNA16	-8289.0
TPR	-8306.0
IL17A	-8312.0
SDC1	-8515.0
CASP1	-8599.0
DPEP1	-8653.0
PARP6	-8734.0
TUBB8	-8794.0
CD3G	-8854.0
ZDHHC11	-8875.0
IFNA13	-8927.0
RPL13A	-9002.5
IL1A	-9007.0
ADCY5	-9051.0
CTSG	-9290.0
RPL7A	-9413.0
CD4	-9499.0
CD28	-9518.0
GNAZ	-9543.0
CCR5	-9630.0
FXYD4	-9697.0
PSMB11	-9711.0
IFNA7	-9715.0
APOBEC3G	-9729.0
IFNA2	-9833.0
IFNA6	-9942.0
IFNA1	-10069.0
GNB3	-10145.0
IFNA8	-10225.0
FCGR3A	-10340.0
POLR2J	-10431.0
MBL2	-10445.0

---

REACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53

REACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53

	591
set	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53
setSize	351
pANOVA	1.06e-08
s.dist	0.178
p.adjustANOVA	1.34e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TAF7	11408
NDUFA4	11315
DDIT4	11147
CASP10	11122
BTG2	10817
ELOC	10605
HIPK1	10586
CDC25C	10524
TXN	10424
POU4F2	10407
ELOB	10398
BAX	10307
COX6A1	10262
PRKAG1	10252
PLK3	10236
CNOT8	10145
RGCC	10050
MAP2K6	9884
FOS	9823
CSNK2A1	9778

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TAF7	11408
NDUFA4	11315
DDIT4	11147
CASP10	11122
BTG2	10817
ELOC	10605
HIPK1	10586
CDC25C	10524
TXN	10424
POU4F2	10407
ELOB	10398
BAX	10307
COX6A1	10262
PRKAG1	10252
PLK3	10236
CNOT8	10145
RGCC	10050
MAP2K6	9884
FOS	9823
CSNK2A1	9778
TNFRSF10B	9724
PRR5	9679
TACO1	9568
COX5B	9564
PIP4P1	9547
SUPT4H1	9529
BIRC5	9463
POLR2C	9358
TNRC6B	9323
SESN3	9305
PRKAA1	9265
GLS2	9199
CCNB1	9175
LAMTOR4	9078
MEAF6	9007
LAMTOR1	8990
UBB	8935
KMT5A	8915
TP53RK	8899
JUN	8891
COX6B1	8837
AURKA	8822
PLK2	8667
GPI	8647
RRAGA	8589
PCNA	8551
POLR2G	8490
BCL6	8442
GADD45A	8412
ING2	8370
BARD1	8265
CCNK	8203
CCNH	8147
BRPF1	8111
PRDM1	8097
SCO1	8009
SUPT16H	8002
TP53	7995
E2F1	7979
RPA3	7810
CNOT6	7759
DYRK2	7726
RPA2	7679
COX14	7670
DAXX	7619
MDM4	7582
GATAD2B	7509
DDB2	7500
RAD9B	7481
CHD3	7459
PPP1R13L	7435
RNF34	7366
SCO2	7311
CNOT6L	7270
MOV10	7179
RFC4	7122
TAF5	7067
CCNT2	6992
ARID3A	6976
PRDX1	6971
WRN	6947
PERP	6942
BBC3	6869
CDK5R1	6845
E2F7	6809
CNOT4	6774
CDK7	6742
TTC5	6635
TNFRSF10D	6631
YWHAQ	6594
RBBP8	6518
SESN2	6408
CCNT1	6333
EXO1	6320
SSRP1	6269
COX7C	6211
CSNK2B	6147
RMI1	6032
RBBP4	6026
POLR2I	5881
BLM	5877
HDAC2	5842
TIGAR	5810
KAT5	5792
PDPK1	5751
RFC5	5739
CNOT2	5693
GATAD2A	5679
CDK9	5514
YWHAH	5488
CASP6	5479
CDK1	5463
COX11	5453
PPP2R1A	5421
MAPKAPK5	5347
KAT6A	5343
COX18	5210
TAF12	5134
GTF2H5	5045
ATM	4998
CSNK2A2	4931
TAF9	4813
GLS	4709
CDKN1B	4666
NPM1	4661
PPP2R5C	4656
TNFRSF10A	4563
SMYD2	4532
NELFB	4523
BID	4499
TAF15	4480
PRMT5	4449
CDKN1A	4380
TCEA1	4339
APAF1	4331
AURKB	4328
AGO1	4301
RAD51D	4279
PRMT1	4277
TNRC6A	4276
CNOT3	4227
FANCD2	4136
COX6C	4023
RHNO1	4015
TXNRD1	3982
ZNF385A	3879
TAF4B	3873
PRELID3A	3753
RAD17	3742
RRM2B	3735
TPX2	3724
ATR	3678
YWHAZ	3670
TAF6	3656
POU4F1	3636
RFFL	3618
USP7	3536
SESN1	3504
RABGGTA	3502
TP53INP1	3460
PLAGL1	3452
RBL2	3425
POLR2K	3416
PIP4K2C	3408
ING5	3400
PMAIP1	3313
CNOT9	3310
CNOT11	3226
YWHAG	3187
MSH2	3165
SGK1	3134
PRDX5	3124
CDK13	3106
NDRG1	3105
HDAC1	3086
ZNF420	3063
MTA2	3044
COX5A	3007
CDK2	2988
PRKAB1	2975
TP73	2972
UBA52	2963
LAMTOR5	2820
TNFRSF10C	2813
DNA2	2805
IGFBP3	2803
POLR2B	2795
CRADD	2719
BCL2L14	2717
CHEK1	2585
CREBBP	2578
PRKAB2	2481
CYCS	2424
PTEN	2393
AKT1	2390
MAPKAP1	2338
NELFCD	2322
RAD1	2227
SURF1	2019
RPTOR	1894
RPA1	1885
PPP2CA	1855
JMY	1804
RFC2	1760
GTF2H3	1736
NELFE	1662
ATRIP	1661
PIP4K2A	1613
MNAT1	1602
ELL	1591
LAMTOR2	1570
GPX2	1567
TOPBP1	1558
CASP2	1545
POLR2A	1481
PPP1R13B	1347
RMI2	1319
SFN	1261
CHD4	1146
NBN	1064
EHMT1	955
RFC3	822
EP300	777
CCNA1	745
PML	732
TP53I3	714
TAF3	666
MDM2	617
USP2	577
RRAGC	489
CNOT10	478
PHF20	457
POLR2E	455
POLR2H	334
TAF10	308
ATF2	234
TP53BP2	150
AIFM2	96
MRE11	94
SETD9	-45
COX8A	-109
E2F8	-176
BRCA1	-237
ELOA2	-319
UBC	-323
PPP2R1B	-352
COX20	-406
GTF2H4	-482
AKT3	-509
BANP	-519
POLR2F	-559
RABGGTB	-609
MAPK14	-685
TOP3A	-739
RRAGD	-797
TAF2	-880
COX16	-1036
AGO4	-1047
HUS1	-1084
RHEB	-1111
TNRC6C	-1236
CDKN2A	-1239
MDC1	-1241
FANCC	-1290
ERCC2	-1393
TBP	-1504
GTF2F1	-1517
NOC2L	-1589
SUPT5H	-1673
ERCC3	-1766
HIPK2	-1861
LRPPRC	-1887
CDK5	-1923
BRIP1	-1946
RBL1	-2049
POLR2D	-2050
CTDP1	-2116
TFDP1	-2145
PIP4K2B	-2159
BRPF3	-2206
AGO3	-2452
YWHAB	-2453
TFDP2	-2551
COX19	-2574
RICTOR	-2579
CCNE2	-2648
TP63	-2651
TRIAP1	-2946
MLH1	-2991
PRKAG2	-3173
PMS2	-3201
TSC2	-3226
RAD9A	-3359
PIDD1	-3362
POLR2L	-3453
TMEM219	-3478
MAPK11	-3633
BNIP3L	-3635
GTF2H1	-3725
NELFA	-3739
EHMT2	-3897
ELOA	-3967
FAS	-4051
PCBP4	-4281
TNKS1BP1	-4286
PIN1	-4308
TSC1	-4355
CCNA2	-4363
TAF13	-4372
MBD3	-4382
PRELID1	-4393
SLC38A9	-4478
COX7A2L	-4486
GSR	-4610
PPP2CB	-4627
YWHAE	-4657
CDK12	-4819
GTF2F2	-4849
RAD50	-5022
FANCI	-5307
CARM1	-5492
MTOR	-5798
CNOT1	-5830
CHEK2	-5952
TAF11	-6014
TAF1L	-6023
CCNG1	-6092
CENPJ	-6375
AKT2	-6463
RPS27A	-6484
COX4I1	-6540
CNOT7	-6586
PRKAA2	-6662
MLST8	-6702
BRD1	-6710
TAF4	-6750
NLRC4	-6854
NUAK1	-7030
LAMTOR3	-7041
AGO2	-7172
PRDX2	-7552
E2F4	-7591
BRD7	-7614
CCNE1	-7855
STK11	-8147
CASP1	-8599
PRKAG3	-9191
STEAP3	-9426
L3MBTL1	-9606
TP53AIP1	-9798
POLR2J	-10431

---

REACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS

REACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS

	1476
set	REACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS
setSize	83
pANOVA	3.32e-08
s.dist	0.351
p.adjustANOVA	3.89e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CEBPA	10979.0
H3-3A	10816.0
LEF1	10638.0
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
H3C12	9726.0
H2BC21	9693.0
RARA	9534.0
FLI1	9509.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CEBPA	10979.0
H3-3A	10816.0
LEF1	10638.0
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
H3C12	9726.0
H2BC21	9693.0
RARA	9534.0
FLI1	9509.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
IL6R	9288.0
H2AZ1	9026.0
H2AC20	9019.0
SPI1	9010.0
CEBPE	8801.0
CEBPB	8485.0
E2F1	7979.0
H3C4	7677.0
MYB	7392.0
H2BC11	7363.0
H2BC5	7354.0
RXRA	7109.0
MYC	7102.0
H2BC3	6877.0
CBFB	6811.0
H4C1	6505.0
STAT3	6128.0
H4C2	5849.0
H2AJ	5832.0
H2AX	5821.0
H4C12	5591.0
H4C8	5375.0
DEK	5370.0
CDKN1A	4380.0
H3C6	4303.0
GFI1	4135.0
H2AZ2	4022.0
RUNX1	3122.0
KLF5	3045.0
CDK2	2988.0
H2BC1	2654.0
H3C10	2553.0
KMT2A	2369.0
H2BC10	2021.0
GATA2	1695.0
EP300	777.0
H3C1	733.0
PML	732.0
H4C11	725.0
H4C5	654.0
H2BC12	519.0
H3C11	416.0
H4C4	162.0
CREB1	-314.0
H3C8	-350.0
CDK4	-1880.0
TFDP1	-2145.0
TAL1	-2319.0
TFDP2	-2551.0
H4C6	-3817.0
H3C3	-4506.0
H2BC26	-4831.0
H2AC18	-5415.5
H2AC19	-5415.5
H4C13	-6090.0
H2BC14	-7223.0
H2BC13	-7559.0
H2AC14	-7938.0
H4C9	-8005.0
CSF3R	-8610.0

---

REACTOME_ADAPTIVE_IMMUNE_SYSTEM

REACTOME_ADAPTIVE_IMMUNE_SYSTEM

	79
set	REACTOME_ADAPTIVE_IMMUNE_SYSTEM
setSize	729
pANOVA	7.98e-08
s.dist	0.117
p.adjustANOVA	8.74e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TYROBP	11454
CD79A	11420
S100A9	11238
LCK	11223
TREML2	11193
ZNRF1	11133
IFITM1	11055
UBA7	11003
GRAP2	10992
UFL1	10964
CD14	10922
CD300LB	10894
KIR2DL4	10866
KIR3DL2	10760
RNF144B	10691
KLHL21	10674
ICAM5	10665
SLAMF6	10629
ELOC	10605
PPP2R5B	10604

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TYROBP	11454.0
CD79A	11420.0
S100A9	11238.0
LCK	11223.0
TREML2	11193.0
ZNRF1	11133.0
IFITM1	11055.0
UBA7	11003.0
GRAP2	10992.0
UFL1	10964.0
CD14	10922.0
CD300LB	10894.0
KIR2DL4	10866.0
KIR3DL2	10760.0
RNF144B	10691.0
KLHL21	10674.0
ICAM5	10665.0
SLAMF6	10629.0
ELOC	10605.0
PPP2R5B	10604.0
UBE2O	10500.0
SIAH1	10498.0
HLA-DMA	10447.0
HERC6	10428.0
HLA-B	10426.0
ELOB	10398.0
TUBB4B	10395.0
FBXW9	10332.0
CD247	10245.0
RAB7A	10227.0
RNF114	10213.0
MYLIP	10179.0
THEM4	10157.0
FBXO2	10103.0
PSMD13	10036.0
RNF7	10011.0
CTSL	10003.0
BECN1	9905.0
FBXO44	9891.0
HLA-DRB5	9867.0
MEX3C	9858.0
HLA-DMB	9819.0
PIK3R1	9796.0
CLEC2D	9788.0
ULBP3	9777.0
UBE2R2	9758.0
FBXO4	9716.0
PRKACB	9713.0
LY96	9708.0
CD22	9689.0
CD33	9687.0
PRR5	9679.0
ANAPC10	9626.0
KLRK1	9612.0
NRAS	9561.0
FBXO17	9542.0
KIF20A	9474.0
MADCAM1	9468.0
AP1S3	9436.0
SOCS3	9415.0
TUBB6	9322.0
LAG3	9310.0
FBXO27	9308.0
B2M	9299.0
CSK	9222.0
UBE2S	9214.0
FBXO41	9192.0
FBXL14	9191.0
CD1D	9172.0
CD101	9110.0
CD3E	9089.0
CALR	9075.0
PILRB	8965.0
UBB	8935.0
MYD88	8923.0
RAP1B	8908.0
RAC1	8876.0
MAP3K14	8848.0
KIF11	8780.0
STIM1	8729.0
HSPA5	8652.0
PSMA6	8609.0
ITGB7	8598.0
LRR1	8583.0
CDC23	8577.0
BTN1A1	8558.0
HLA-E	8552.0
ITGB2	8550.0
CTLA4	8505.0
DCTN6	8494.0
TUBA4B	8469.0
ULBP1	8449.0
UBE2J1	8379.0
HLA-F	8377.0
BTN2A2	8366.0
DYNC1LI2	8336.0
CTSV	8307.0
TLR2	8292.0
FBXO6	8278.0
TLR6	8256.0
SOCS1	8254.0
SIPA1	8208.0
RNF41	8200.0
RNF126	8195.0
PSMC6	8173.0
DTX3L	8157.0
RNF123	8106.0
PIANP	8085.0
CDC26	8079.0
HLA-DQA1	8072.0
UBE2N	8070.0
UBE2F	8046.0
IFI30	8033.0
FBXL15	8030.0
TUBA8	8019.0
ICAM1	8008.0
KIF23	8000.0
CTSO	7886.0
PTPRJ	7882.0
PTPN11	7860.0
MALT1	7857.0
ITK	7837.0
FBXO40	7828.0
SIAH2	7792.0
PSME3	7776.0
RBBP6	7765.0
UBE2G1	7751.0
FBXW2	7734.0
FYB1	7693.0
CD86	7659.0
HERC1	7563.0
NCF2	7558.0
FBXL16	7516.0
CD19	7507.0
TUBB4A	7468.0
ICAM4	7454.0
PPP2R5A	7419.0
UBE2E1	7409.0
INPP5D	7403.0
TUBA4A	7384.0
RNF34	7366.0
S100A8	7358.0
KCTD7	7350.0
ICAM3	7343.0
DNM2	7321.0
FBXO7	7315.0
TRIM37	7245.0
PIK3AP1	7202.0
UBA5	7184.0
DCTN1	7164.0
NFKBIA	7150.0
SIGLEC9	7138.0
MAP3K8	7115.0
CD200	7093.0
PDCD1LG2	7073.0
LRRC41	7036.0
NCR3	7012.0
SAR1B	6986.0
HCST	6983.0
FBXL8	6943.0
RBCK1	6933.0
DYNLL2	6886.0
TUBB3	6871.0
SNAP23	6848.0
PSMB3	6752.0
EVL	6699.0
PSMD12	6656.0
SELL	6644.0
SEC61B	6637.0
CANX	6634.0
REL	6596.0
FBXW4	6509.0
LYN	6506.0
FBXL18	6456.0
TRIM32	6445.0
DYNC1LI1	6419.0
AP1M1	6413.0
CDC42	6406.0
HLA-A	6401.0
LAIR1	6349.0
FBXL3	6332.0
ITPR2	6297.0
KIFAP3	6296.0
SEC23A	6281.0
BTLA	6271.0
CD8B	6262.0
HLA-DPB1	6257.0
CD1B	6159.0
CLTA	6146.0
ANAPC7	6124.0
ASB17	6101.0
PIK3R2	6055.0
PSMB7	6049.0
SEC24A	6013.0
UBE2Q2	5999.0
TRIM69	5979.0
PAG1	5961.0
LILRA3	5960.0
UBR2	5942.0
S100A1	5936.0
KBTBD8	5876.0
PPP3CA	5845.0
NCR2	5820.0
KIF5A	5804.0
DAPP1	5796.0
CCNF	5786.0
ANAPC2	5784.0
NEDD4	5782.0
HLA-DOB	5758.0
PDPK1	5751.0
UBE2G2	5744.0
TRIM36	5742.0
SEC31A	5730.0
LNPEP	5689.0
UBA6	5671.0
BTNL8	5670.0
AREL1	5656.0
RNF111	5654.0
PAK1	5648.0
ANAPC11	5571.0
RAP1A	5538.0
PSMC1	5452.0
MGRN1	5427.0
PPP2R1A	5421.0
FZR1	5395.0
ACTR10	5394.0
RNF6	5374.0
GLMN	5365.0
TUBB2A	5342.0
KLHL3	5335.0
BLMH	5319.0
TUBA3C	5315.0
LCP2	5302.0
CD34	5289.0
HLA-G	5246.0
NFKB1	5242.0
CD79B	5231.0
ANAPC13	5208.0
CD300E	5195.0
SEC24B	5187.0
PRKCB	5164.0
CUL3	5141.0
CUL2	5114.0
UBA3	5109.0
FBXO30	5088.0
PSMD8	5087.0
BTN3A3	5033.0
CTSK	5006.0
LILRB3	4954.0
SEC61G	4933.0
KLHL42	4929.0
TRIP12	4859.5
CTSA	4855.0
CD81	4823.0
JAML	4788.0
AP2A1	4785.0
SLAMF7	4782.0
AP2B1	4781.0
UBE2D4	4768.0
UBE3A	4758.0
PIK3CD	4745.0
FBXO32	4726.0
KIF18A	4714.0
FBXO22	4685.0
FGB	4682.0
CLEC2B	4677.0
ASB8	4662.0
PPP2R5C	4656.0
HMGB1	4642.0
PSMB10	4635.0
GAN	4615.0
BTRC	4547.0
CALM1	4537.0
UBE2D2	4497.0
PSMD3	4433.0
CD274	4431.0
CDC27	4430.0
UBE2C	4394.0
ITGA4	4351.0
UBOX5	4350.0
CENPE	4344.0
DYNC1H1	4333.0
DYNC1I1	4315.0
AP2S1	4300.0
AP1M2	4299.0
UBE2V1	4269.0
TRIM63	4241.0
CD8A	4231.0
RASGRP3	4226.0
UBE2D3	4215.0
MICA	4174.0
PSMA3	4156.0
CUL1	4104.0
CTSD	4081.0
TRIM4	4018.0
ITPR1	3976.0
ASB6	3951.0
PSMC2	3840.0
TRIM9	3833.0
RILP	3830.0
UBE2H	3736.0
COL2A1	3703.0
DYNC1I2	3671.0
YWHAZ	3670.0
RNF14	3666.0
ERAP1	3655.0
VASP	3644.0
SRC	3558.0
KIF5B	3535.0
MAP3K7	3513.0
LAT	3488.0
CARD11	3446.0
FBXL19	3346.0
TIRAP	3308.0
FBXW11	3290.0
KEAP1	3287.0
ZNRF2	3279.0
SMURF1	3156.0
DCTN2	3142.0
PSMC5	3099.0
PTPN22	3061.0
STX4	3018.0
FBXL5	2993.0
BTNL9	2985.0
VAV1	2979.0
UBA52	2963.0
DZIP3	2962.0
PSMB1	2960.0
LONRF1	2916.0
FBXL4	2915.0
FBXO15	2898.0
GRB2	2858.0
LTN1	2853.0
UBE2W	2838.0
ANAPC4	2830.0
MIB2	2800.0
KLRG1	2791.0
SKP2	2789.0
NCK1	2788.0
CXADR	2751.0
UBR4	2712.0
NFKBIB	2703.0
ASB3	2693.0
OSCAR	2677.0
ASB14	2653.0
BTN3A2	2607.0
UBE2K	2605.0
PSMB2	2596.0
ACTR1B	2577.0
LAIR2	2535.0
ORAI1	2523.0
PSMA1	2497.0
TREM1	2459.0
PSMB5	2455.0
PSMD2	2443.0
PSMA7	2417.0
NFATC2	2401.0
PTEN	2393.0
AKT1	2390.0
CD96	2370.0
DYNLL1	2349.0
MICB	2342.0
MAPKAP1	2338.0
TPP2	2320.0
PSMB4	2281.0
HERC5	2263.0
KBTBD6	2248.0
KLHL5	2243.0
TRIM39	2218.0
CYBA	2203.0
ASB13	2183.0
UBE3C	2166.0
SEC22B	2144.0
FBXL22	2070.0
PSMD4	2042.0
VAMP3	2037.0
SPSB2	2004.0
KLC1	1988.0
UNKL	1971.0
PIK3R4	1925.0
SMURF2	1884.0
ARIH2	1876.0
PPP2CA	1855.0
CLTC	1791.0
DCTN5	1751.0
ICAM2	1745.0
SPSB1	1741.0
WWP1	1718.0
KIF15	1650.0
KLRB1	1588.0
KIF2C	1583.0
PSME1	1571.0
SKP1	1543.0
RAF1	1469.0
KRAS	1468.0
ITGAV	1426.0
OSBPL1A	1395.0
UBE2M	1374.0
HECTD3	1324.0
KLRD1	1286.0
TRAF7	1253.0
PSME2	1245.0
ORAI2	1237.0
RCHY1	1233.0
PSMA2	1218.0
TRIM71	1207.0
PSMB6	1163.0
UBE2L6	1124.0
TRAF6	1095.0
TUBB1	1042.0
TLR1	1019.0
FBXW5	1016.0
TUBAL3	971.0
AP1S1	957.0
LNX1	891.0
UBE3D	872.0
RASGRP1	830.0
AP1G1	827.0
RACGAP1	792.0
LILRB4	675.0
AHCYL1	629.0
FBXO10	622.0
HLA-DQB2	602.0
CBLB	592.0
RAP1GAP2	583.0
PDIA3	575.0
RELA	572.0
DET1	562.0
UBE2D1	557.0
PPL	555.0
KIF3C	527.0
CDC16	525.0
CD74	513.0
ACTR1A	495.0
ZBTB16	437.0
SYK	418.0
NPEPPS	413.0
COL1A1	412.0
SEC24D	369.0
MKRN1	368.0
NFATC3	347.0
SEM1	329.0
BLK	314.0
TUBA1B	276.0
KLHL22	140.0
UBE2B	105.0
KLC4	104.0
FBXL12	68.0
KLHL25	-49.0
PSMB8	-53.0
TRPC1	-67.0
STUB1	-163.0
UBAC1	-195.0
PLCG2	-204.0
ITGB1	-205.0
KLHL2	-247.0
ITPR3	-266.0
UBE4A	-305.0
UBC	-323.0
VHL	-326.0
SEC61A1	-335.0
PPP2R1B	-352.0
RNF25	-368.0
KIF3B	-371.0
CLEC4G	-386.0
PSMD5	-411.0
TRIM11	-454.0
CAPZB	-478.0
CUL7	-486.0
AKT3	-509.0
HECTD1	-524.0
FBXO9	-529.0
PSMA5	-534.0
ANAPC1	-538.0
TRIM41	-546.0
SIGLEC12	-556.0
CUL5	-608.0
UBE2E2	-637.0
RNF4	-646.0
SEC24C	-674.0
BCL10	-688.0
PSMB9	-734.0
HERC4	-769.0
PSME4	-771.0
FKBP1A	-804.0
PSMD11	-805.0
DCTN4	-808.0
PPP3CB	-810.0
PIK3CA	-820.0
SOS1	-853.0
CD160	-865.0
BLNK	-929.0
CDH1	-945.0
ATG7	-959.0
KIR3DL1	-993.0
HECTD2	-1035.0
NCF4	-1049.0
KLC3	-1108.0
CD209	-1157.0
PPP2R5E	-1166.0
ATG14	-1169.0
PLCG1	-1251.0
HLA-DQB1	-1298.0
UBE2E3	-1308.0
PPIA	-1344.0
UBE2U	-1382.0
NFATC1	-1406.0
CAPZA1	-1417.0
COL1A2	-1423.0
TAPBP	-1446.0
TAP2	-1499.0
KLHL11	-1521.0
UBE3B	-1562.0
CD300A	-1573.0
PRKCQ	-1576.0
HERC3	-1611.0
HLA-DQA2	-1661.0
BTBD1	-1667.0
RNF19A	-1672.0
VAMP8	-1697.0
PPP2R5D	-1720.0
CTSH	-1819.0
ASB16	-1846.0
CTSB	-1891.0
SIGLEC6	-1920.0
PSMD7	-1937.0
HLA-DRB1	-1940.0
AP2M1	-1978.0
AP2A2	-2041.0
FBXW8	-2052.0
TAB2	-2055.0
FBXW7	-2124.0
KLHL9	-2151.0
RNF130	-2175.0
FBXO11	-2211.0
UBR1	-2219.0
SFTPD	-2222.0
PRKG1	-2259.0
KCTD6	-2265.0
ZAP70	-2268.0
AP1B1	-2324.0
FBXL13	-2328.0
TAP1	-2361.0
TLR4	-2385.0
PRKN	-2446.0
YWHAB	-2453.0
CAPZA2	-2480.0
HLA-DPA1	-2492.0
PIK3R3	-2501.0
RAPGEF3	-2536.0
HLA-C	-2543.0
RICTOR	-2579.0
CRTAM	-2583.0
CD300LD	-2604.0
TRIB3	-2707.0
MRC2	-2735.0
KIF3A	-2745.0
HLA-DRA	-2747.0
COLEC12	-2830.0
HACE1	-2836.0
NCR1	-2895.0
PSMD9	-2906.0
TREML4	-2910.0
RAP1GAP	-2914.0
IKBKB	-2956.0
NCR3LG1	-2973.0
CD200R1	-2997.0
LRSAM1	-3017.0
ITCH	-3047.0
FBXO31	-3115.0
CDC20	-3146.0
UBE2Q1	-3197.0
PIK3C3	-3214.0
FBXW12	-3218.0
PRKACA	-3280.0
PTPRC	-3375.0
KIF22	-3390.0
SH2D1B	-3420.0
RNF19B	-3466.0
LILRA4	-3486.0
ANAPC5	-3528.0
ERAP2	-3529.0
TUBA1A	-3578.0
CD1C	-3586.0
BTN2A1	-3625.0
ASB1	-3654.0
UBE2L3	-3724.0
RASGRP2	-3779.0
DCAF1	-3787.0
TUBA3E	-3827.0
SH3GL2	-3909.0
KLC2	-3925.0
FBXL7	-3947.0
CD80	-4012.0
PVR	-4022.0
TRAIP	-4038.0
SIGLEC11	-4041.0
FBXL20	-4043.0
TUBA1C	-4095.0
HRAS	-4103.0
SH3RF1	-4197.0
PPP3R1	-4203.0
DNM3	-4222.0
LGMN	-4268.0
KIF2B	-4290.0
HECW2	-4294.0
PSMC3	-4492.0
FYN	-4554.0
KIF4B	-4604.0
FBXO21	-4616.0
PPP2CB	-4627.0
C3	-4674.0
ASB7	-4692.0
PJA2	-4701.0
RNF220	-4804.0
TUBA3D	-4880.0
UBE2V2	-4928.0
LMO7	-4958.0
CD300LG	-5003.0
UBE2Z	-5148.0
KLHL20	-5233.0
RNF182	-5239.0
PSMD14	-5297.0
CHUK	-5332.0
HLA-DOA	-5350.0
HERC2	-5391.0
NECTIN2	-5446.0
RIPK2	-5497.0
PSMD1	-5508.0
RNF138	-5583.0
YES1	-5604.0
BTNL2	-5610.0
PTPN6	-5631.0
PSMD6	-5633.0
PSMF1	-5638.0
COL3A1	-5646.0
KBTBD7	-5701.0
CTSC	-5762.0
MTOR	-5798.0
RNF115	-5814.0
ITGAL	-5932.0
CTSE	-5942.0
KIF26A	-5979.0
RNF217	-6005.0
NFKBIE	-6034.0
ASB2	-6127.0
UBE2J2	-6144.0
THOP1	-6239.0
XDH	-6377.0
PILRA	-6397.0
CD1A	-6449.0
AKT2	-6463.0
NEDD4L	-6474.0
RPS27A	-6484.0
PSMA8	-6587.0
SIGLEC5	-6603.0
ASB15	-6611.0
PSMC4	-6643.0
RAPGEF4	-6690.0
MLST8	-6702.0
PIK3CB	-6722.0
ASB18	-6738.0
PDCD1	-6766.0
SEC13	-6814.0
RBX1	-6897.0
RAET1E	-6898.0
RNF213	-7077.0
ITGB5	-7109.0
DCTN3	-7114.0
LILRA5	-7132.0
PAK2	-7196.0
PSMA4	-7243.0
PRKACG	-7244.0
ASB4	-7276.0
SPSB4	-7316.0
TUBB2B	-7326.0
COL17A1	-7374.0
ENAH	-7377.0
KIF2A	-7387.0
KLRF1	-7403.0
LILRA2	-7448.0
ASB5	-7467.0
WSB1	-7487.0
DNM1	-7533.0
NPDC1	-7558.0
BTN3A1	-7669.0
CTSS	-7691.0
KLHL41	-7761.0
ARF1	-7806.0
LILRB5	-7949.0
TRAT1	-8122.0
CDC34	-8133.0
SIGLEC8	-8260.0
TREML1	-8284.0
KIR2DL1	-8303.0
SIGLEC7	-8305.0
TREM2	-8358.0
SEC61A2	-8415.0
TRIM50	-8426.0
CD300LF	-8690.0
ASB10	-8729.0
SPTBN2	-8740.0
TUBB8	-8794.0
CTSF	-8798.0
LILRB1	-8812.0
SIGLEC10	-8820.0
CD3G	-8854.0
FBXW10	-9010.0
CD40	-9019.0
CD226	-9049.0
CD36	-9061.0
LILRB2	-9103.0
CAPZA3	-9138.0
FGA	-9164.0
BTBD6	-9173.0
TRIM21	-9335.0
CD300C	-9379.0
VCAM1	-9458.0
CD4	-9499.0
CD28	-9518.0
PSMB11	-9711.0
LILRA1	-9874.0
FGG	-9928.0
CD3D	-9987.0
ICOS	-10100.0
KLRC1	-10103.0
SIGLEC1	-10211.0
FCGR3A	-10340.0
CD207	-10363.0

---

REACTOME_SENESCENCE_ASSOCIATED_SECRETORY_PHENOTYPE_SASP

REACTOME_SENESCENCE_ASSOCIATED_SECRETORY_PHENOTYPE_SASP

	502
set	REACTOME_SENESCENCE_ASSOCIATED_SECRETORY_PHENOTYPE_SASP
setSize	104
pANOVA	1.13e-07
s.dist	0.301
p.adjustANOVA	1.15e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H3-3A	10816.0
CDKN2D	10796.0
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
FOS	9823.0
H3C12	9726.0
H2BC21	9693.0
ANAPC10	9626.0
H2BC8	9455.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H3-3A	10816.0
CDKN2D	10796.0
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
FOS	9823.0
H3C12	9726.0
H2BC21	9693.0
ANAPC10	9626.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
VENTX	9327.0
UBE2S	9214.0
RPS6KA1	9141.0
CDKN2B	9139.0
CDKN2C	9068.0
H2AZ1	9026.0
H2AC20	9019.0
UBB	8935.0
JUN	8891.0
CDC23	8577.0
CEBPB	8485.0
CDC26	8079.0
IL6	7762.0
H3C4	7677.0
UBE2E1	7409.0
H2BC11	7363.0
H2BC5	7354.0
H2BC3	6877.0
H4C1	6505.0
STAT3	6128.0
ANAPC7	6124.0
H4C2	5849.0
H2AJ	5832.0
H2AX	5821.0
ANAPC2	5784.0
H4C12	5591.0
ANAPC11	5571.0
FZR1	5395.0
H4C8	5375.0
NFKB1	5242.0
ANAPC16	4927.0
CDKN1B	4666.0
CDC27	4430.0
UBE2C	4394.0
CDKN1A	4380.0
H3C6	4303.0
H2AZ2	4022.0
CDK2	2988.0
UBA52	2963.0
ANAPC4	2830.0
H2BC1	2654.0
H3C10	2553.0
H2BC10	2021.0
CXCL8	1749.0
MAPK7	1493.0
EHMT1	955.0
MAPK3	901.0
CCNA1	745.0
H3C1	733.0
H4C11	725.0
H4C5	654.0
RELA	572.0
UBE2D1	557.0
CDC16	525.0
H2BC12	519.0
H3C11	416.0
H4C4	162.0
UBC	-323.0
H3C8	-350.0
CDK6	-504.0
ANAPC1	-538.0
RPS6KA2	-899.0
CDKN2A	-1239.0
MAPK1	-1794.0
CDK4	-1880.0
ANAPC5	-3528.0
ANAPC15	-3556.0
H4C6	-3817.0
EHMT2	-3897.0
CCNA2	-4363.0
H3C3	-4506.0
H2BC26	-4831.0
H2AC18	-5415.5
H2AC19	-5415.5
IGFBP7	-5937.0
H4C13	-6090.0
RPS27A	-6484.0
H2BC14	-7223.0
H2BC13	-7559.0
H2AC14	-7938.0
H4C9	-8005.0
IL1A	-9007.0

---

REACTOME_CELLULAR_SENESCENCE

REACTOME_CELLULAR_SENESCENCE

	503
set	REACTOME_CELLULAR_SENESCENCE
setSize	189
pANOVA	1.19e-07
s.dist	0.223
p.adjustANOVA	1.15e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H3-3A	10816.0
CDKN2D	10796.0
H2AC4	10558.0
ETS2	10521.0
H2BC17	10497.0
ID1	10480.0
H1-3	10469.0
TXN	10424.0
H4C16	10315.0
H2BC15	10314.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
MAP2K6	9884.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H3-3A	10816.0
CDKN2D	10796.0
H2AC4	10558.0
ETS2	10521.0
H2BC17	10497.0
ID1	10480.0
H1-3	10469.0
TXN	10424.0
H4C16	10315.0
H2BC15	10314.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
MAP2K6	9884.0
FOS	9823.0
H3C12	9726.0
H2BC21	9693.0
ANAPC10	9626.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
VENTX	9327.0
TNRC6B	9323.0
UBE2S	9214.0
RPS6KA1	9141.0
CDKN2B	9139.0
CDKN2C	9068.0
H2AZ1	9026.0
H2AC20	9019.0
UBB	8935.0
JUN	8891.0
KDM6B	8750.0
ERF	8606.0
H1-0	8604.0
CDC23	8577.0
CEBPB	8485.0
RNF2	8302.0
MIR24-2	8125.0
CDC26	8079.0
TP53	7995.0
E2F1	7979.0
IL6	7762.0
H3C4	7677.0
MDM4	7582.0
UBE2E1	7409.0
MIR24-1	7385.0
H2BC11	7363.0
H2BC5	7354.0
MOV10	7179.0
MAPKAPK2	7010.0
H2BC3	6877.0
CBX4	6802.0
TNIK	6663.0
H4C1	6505.0
BMI1	6356.0
STAT3	6128.0
ANAPC7	6124.0
RBBP4	6026.0
CBX2	5858.0
H4C2	5849.0
H2AJ	5832.0
H2AX	5821.0
KAT5	5792.0
ANAPC2	5784.0
H4C12	5591.0
ANAPC11	5571.0
MAP4K4	5456.0
FZR1	5395.0
H4C8	5375.0
MAPKAPK5	5347.0
NFKB1	5242.0
POT1	5008.0
ATM	4998.0
ANAPC16	4927.0
CDKN1B	4666.0
MAPK9	4542.0
CDC27	4430.0
UBE2C	4394.0
CDKN1A	4380.0
H3C6	4303.0
AGO1	4301.0
IFNB1	4295.0
TNRC6A	4276.0
H2AZ2	4022.0
MAPK8	3772.0
ACD	3521.5
H1-5	3242.0
UBN1	3233.0
CDK2	2988.0
UBA52	2963.0
ANAPC4	2830.0
H2BC1	2654.0
PHC1	2610.0
H3C10	2553.0
SCMH1	2508.0
TERF2IP	2334.0
MAPKAPK3	2205.0
HMGA2	2040.0
H2BC10	2021.0
H1-1	2008.0
E2F3	1797.0
CXCL8	1749.0
MAPK7	1493.0
RB1	1335.0
CBX8	1158.0
NBN	1064.0
SP1	1043.0
ETS1	1038.0
TERF1	989.0
EHMT1	955.0
MAPK3	901.0
CCNA1	745.0
H3C1	733.0
H4C11	725.0
H4C5	654.0
MDM2	617.0
RELA	572.0
UBE2D1	557.0
CDC16	525.0
H2BC12	519.0
H3C11	416.0
EZH2	243.0
H4C4	162.0
MRE11	94.0
MAP2K3	0.0
UBC	-323.0
H3C8	-350.0
CDK6	-504.0
ANAPC1	-538.0
H1-2	-661.0
MAPK14	-685.0
RING1	-719.0
RPS6KA2	-899.0
PHC3	-931.0
AGO4	-1047.0
TNRC6C	-1236.0
CDKN2A	-1239.0
EED	-1311.0
MAP3K5	-1368.0
TINF2	-1596.0
MAPK1	-1794.0
CDK4	-1880.0
E2F2	-2047.0
TFDP1	-2145.0
AGO3	-2452.0
EP400	-2491.0
TFDP2	-2551.0
HMGA1	-2614.0
CCNE2	-2648.0
HIRA	-2981.0
LMNB1	-3282.0
MAP2K7	-3436.0
MAPK10	-3465.0
ASF1A	-3475.0
MAP2K4	-3501.0
ANAPC5	-3528.0
ANAPC15	-3556.0
MAPK11	-3633.0
H1-4	-3737.0
H4C6	-3817.0
EHMT2	-3897.0
MINK1	-4279.0
PHC2	-4284.0
CCNA2	-4363.0
H3C3	-4506.0
H3-4	-4773.0
H2BC26	-4831.0
SUZ12	-4896.0
RAD50	-5022.0
TERF2	-5078.0
CBX6	-5151.0
H2AC18	-5415.5
H2AC19	-5415.5
IGFBP7	-5937.0
H4C13	-6090.0
RPS27A	-6484.0
CABIN1	-6536.0
H2BC14	-7223.0
H2BC13	-7559.0
CCNE1	-7855.0
H2AC14	-7938.0
H4C9	-8005.0
IL1A	-9007.0

---

REACTOME_M_PHASE

REACTOME_M_PHASE

	1096
set	REACTOME_M_PHASE
setSize	398
pANOVA	4.53e-07
s.dist	0.147
p.adjustANOVA	4.13e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CHMP4C	11134
USO1	10970
CSNK1E	10909
H3-3A	10816
PPP2R5B	10604
MZT2B	10599
H2AC4	10558
H2BC17	10497
TUBB4B	10395
H4C16	10315
H2BC15	10314
CTDNEP1	10173
RAN	10098
H3-3B	10095
H4C3	10086
H2AC6	10052
H3C2	10037
PSMD13	10036
TUBG1	10027
H2BC4	9994

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CHMP4C	11134.0
USO1	10970.0
CSNK1E	10909.0
H3-3A	10816.0
PPP2R5B	10604.0
MZT2B	10599.0
H2AC4	10558.0
H2BC17	10497.0
TUBB4B	10395.0
H4C16	10315.0
H2BC15	10314.0
CTDNEP1	10173.0
RAN	10098.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
PSMD13	10036.0
TUBG1	10027.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
NSL1	9840.0
CSNK2A1	9778.0
SGO1	9752.0
H3C12	9726.0
H2BC21	9693.0
ANAPC10	9626.0
KIF20A	9474.0
POM121	9464.0
BIRC5	9463.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
NEK6	9352.0
TUBB6	9322.0
UBE2S	9214.0
TUBG2	9179.0
CCNB1	9175.0
SIRT2	9130.0
MASTL	9071.0
H2AZ1	9026.0
H2AC20	9019.0
RAB1B	8943.0
UBB	8935.0
KMT5A	8915.0
CENPC	8675.0
HAUS2	8672.0
PSMA6	8609.0
CDC23	8577.0
ZW10	8484.0
TUBA4B	8469.0
CENPH	8445.0
KPNB1	8399.0
DYNC1LI2	8336.0
TNPO1	8276.0
PSMC6	8173.0
CDC26	8079.0
RAE1	8059.0
CENPS	8051.0
NUP58	8047.0
TUBA8	8019.0
CEP41	8012.0
KIF23	8000.0
NUP43	7960.0
NUP35	7791.0
PSME3	7776.0
CEP43	7761.0
NUP50	7744.0
BLZF1	7717.0
H3C4	7677.0
RCC1	7522.0
TUBB4A	7468.0
PPP2R5A	7419.0
NEDD1	7410.0
UBE2E1	7409.0
TUBA4A	7384.0
H2BC11	7363.0
H2BC5	7354.0
CHMP2A	7210.0
NCAPG	7209.0
DCTN1	7164.0
NME7	7129.0
CHMP4A	6900.0
MCPH1	6889.0
DYNLL2	6886.0
H2BC3	6877.0
TUBB3	6871.0
CEP250	6859.0
CENPA	6857.0
HAUS1	6787.0
CHMP2B	6780.0
PSMB3	6752.0
PSMD12	6656.0
NUMA1	6650.0
CDCA8	6641.0
NUP88	6529.0
H4C1	6505.0
PLK4	6498.0
DYNC1LI1	6419.0
CENPT	6418.0
CENPM	6270.0
CSNK2B	6147.0
ANAPC7	6124.0
PSMB7	6049.0
NUP155	6039.0
XPO1	5947.0
SPAST	5932.0
LPIN1	5850.0
H4C2	5849.0
H2AJ	5832.0
H2AX	5821.0
ANAPC2	5784.0
VRK2	5692.0
CHMP7	5637.0
SDCCAG8	5605.0
H4C12	5591.0
ANAPC11	5571.0
CDK1	5463.0
PSMC1	5452.0
DSN1	5434.0
PPP2R1A	5421.0
CKAP5	5383.0
H4C8	5375.0
SET	5356.0
TUBB2A	5342.0
TUBA3C	5315.0
ZWILCH	5257.0
VPS4A	5230.0
CDK5RAP2	5227.0
PRKCB	5164.0
PSMD8	5087.0
CSNK2A2	4931.0
ANAPC16	4927.0
NDE1	4740.0
KIF18A	4714.0
RAB1A	4671.0
BANF1	4658.0
PPP2R5C	4656.0
PSMB10	4635.0
ENSA	4581.0
TAOK1	4538.0
CDCA5	4511.0
PSMD3	4433.0
CDC27	4430.0
UBE2C	4394.0
CENPE	4344.0
DYNC1H1	4333.0
AURKB	4328.0
DYNC1I1	4315.0
H3C6	4303.0
PSMA3	4156.0
H2AZ2	4022.0
RAB2A	4004.0
TUBGCP4	3974.0
PSMC2	3840.0
GORASP2	3821.0
B9D2	3791.0
HAUS4	3783.0
PMF1	3768.0
TUBB	3708.0
MZT2A	3702.0
CEP290	3693.0
DYNC1I2	3671.0
NDC80	3635.0
NUP133	3627.0
ESPL1	3625.0
CLASP1	3593.0
NUP160	3568.0
PCM1	3462.0
CEP152	3343.0
CEP63	3302.0
NUP214	3289.0
SPC24	3282.0
YWHAG	3187.0
CHMP3	3159.0
DCTN2	3142.0
PSMC5	3099.0
CEP57	3058.0
NUP188	2995.0
CLASP2	2994.0
CEP70	2984.0
UBA52	2963.0
PSMB1	2960.0
SSNA1	2919.0
PCNT	2859.0
ANAPC4	2830.0
LPIN2	2771.0
KNL1	2766.0
CEP76	2739.0
AKAP9	2716.0
H2BC1	2654.0
LBR	2649.0
PSMB2	2596.0
STAG1	2592.0
H3C10	2553.0
CCNB2	2521.0
MZT1	2513.0
PSMA1	2497.0
PSMB5	2455.0
PSMD2	2443.0
PSMA7	2417.0
DYNLL1	2349.0
SEH1L	2309.0
PLK1	2308.0
SMC4	2289.0
PSMB4	2281.0
PRKCA	2239.0
PSMD4	2042.0
H2BC10	2021.0
ODF2	1921.0
PPP2CA	1855.0
BUB1B	1694.0
CENPO	1592.0
KIF2C	1583.0
PSME1	1571.0
MAPRE1	1549.0
NEK2	1458.0
NUP107	1453.0
NCAPD3	1434.0
PDS5A	1397.0
RB1	1335.0
SMC2	1295.0
PSME2	1245.0
NEK7	1231.0
PSMA2	1218.0
CENPQ	1164.0
PSMB6	1163.0
POM121C	1147.0
NUP62	1081.0
TUBB1	1042.0
NCAPG2	1015.0
NUP85	973.0
TUBAL3	971.0
CNTRL	908.0
MAPK3	901.0
LEMD3	798.0
IST1	783.0
RCC2	742.0
H3C1	733.0
H4C11	725.0
H4C5	654.0
CSNK1D	610.0
UBE2D1	557.0
CDC16	525.0
H2BC12	519.0
MAD1L1	516.0
ACTR1A	495.0
TUBGCP3	441.0
H3C11	416.0
SEM1	329.0
TUBA1B	276.0
CCP110	211.0
AAAS	206.0
H4C4	162.0
PAFAH1B1	139.0
RAD21	23.0
PSMB8	-53.0
PDS5B	-69.0
NUP153	-100.0
TUBGCP2	-185.0
CEP72	-254.0
MIS12	-257.0
UBC	-323.0
H3C8	-350.0
PPP2R1B	-352.0
ARPP19	-377.0
PSMD5	-411.0
CENPL	-455.0
KNTC1	-501.0
PSMA5	-534.0
ANAPC1	-538.0
PPP2R2A	-603.0
RPS27	-651.0
ANKLE2	-687.0
PSMB9	-734.0
PSME4	-771.0
PSMD11	-805.0
NUP98	-843.0
CEP131	-860.0
SGO2	-877.0
CLIP1	-1032.0
PPP2R5E	-1166.0
EML4	-1280.0
NDEL1	-1297.0
NUP205	-1359.0
HAUS8	-1392.0
ALMS1	-1415.0
SKA2	-1465.0
CENPN	-1557.0
PPP2R5D	-1720.0
HAUS6	-1764.0
MAPK1	-1794.0
NEK9	-1833.0
PPP1CC	-1885.0
VRK1	-1901.0
PSMD7	-1937.0
TUBGCP6	-1945.0
NCAPD2	-2122.0
PTTG1	-2237.0
NUP210	-2340.0
CC2D1B	-2395.0
NUDC	-2458.0
HAUS3	-2539.0
NUF2	-2839.0
PSMD9	-2906.0
SUMO1	-3031.0
AHCTF1	-3049.0
CDC20	-3146.0
MAU2	-3169.0
FBXO5	-3238.0
BUB3	-3248.0
PRKACA	-3280.0
LMNB1	-3282.0
LMNA	-3373.0
PRKAR2B	-3491.0
ANAPC5	-3528.0
ANAPC15	-3556.0
TUBA1A	-3578.0
BUB1	-3658.0
CEP164	-3729.0
H4C6	-3817.0
TUBA3E	-3827.0
PPP2R2D	-3904.0
CEP135	-3908.0
TUBGCP5	-3955.0
HSP90AA1	-4000.0
SKA1	-4015.0
TUBA1C	-4095.0
SPDL1	-4219.0
MAD2L1	-4227.0
KIF2B	-4290.0
ITGB3BP	-4330.0
CHMP4B	-4388.0
PSMC3	-4492.0
H3C3	-4506.0
LPIN3	-4588.0
PPP2CB	-4627.0
YWHAE	-4657.0
NIPBL	-4687.0
NDC1	-4745.0
H3-4	-4773.0
H2BC26	-4831.0
CENPU	-4840.0
TUBA3D	-4880.0
CEP192	-4953.0
CEP78	-4974.0
SPC25	-4986.0
HAUS5	-5034.0
NUP42	-5150.0
RANBP2	-5265.0
NINL	-5271.0
PSMD14	-5297.0
NUP37	-5314.0
CENPF	-5361.0
H2AC18	-5415.5
H2AC19	-5415.5
TMPO	-5468.0
PSMD1	-5508.0
PSMD6	-5633.0
PSMF1	-5638.0
NCAPH	-5690.0
NUP93	-5736.0
SFI1	-5747.0
RANGAP1	-5823.0
CENPK	-5871.0
CENPP	-5908.0
LEMD2	-6049.0
GOLGA2	-6063.0
H4C13	-6090.0
NUP54	-6131.0
SMC3	-6169.0
WAPL	-6268.0
ZWINT	-6341.0
CENPJ	-6375.0
RPS27A	-6484.0
PSMA8	-6587.0
PSMC4	-6643.0
SEC13	-6814.0
GORASP1	-6885.0
DCTN3	-7114.0
CNEP1R1	-7168.0
H2BC14	-7223.0
PSMA4	-7243.0
TUBB2B	-7326.0
KIF2A	-7387.0
CHMP6	-7414.0
H2BC13	-7559.0
UBE2I	-7598.0
H2AC14	-7938.0
H4C9	-8005.0
TPR	-8306.0
INCENP	-8317.0
NCAPH2	-8346.0
TUBB8	-8794.0
PSMB11	-9711.0

---

REACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE

REACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE

	501
set	REACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE
setSize	118
pANOVA	4.88e-07
s.dist	0.268
p.adjustANOVA	4.22e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H3-3A	10816.0
CDKN2D	10796.0
H2AC4	10558.0
H2BC17	10497.0
TXN	10424.0
H4C16	10315.0
H2BC15	10314.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
MAP2K6	9884.0
FOS	9823.0
H3C12	9726.0
H2BC21	9693.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H3-3A	10816.0
CDKN2D	10796.0
H2AC4	10558.0
H2BC17	10497.0
TXN	10424.0
H4C16	10315.0
H2BC15	10314.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
MAP2K6	9884.0
FOS	9823.0
H3C12	9726.0
H2BC21	9693.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
TNRC6B	9323.0
CDKN2B	9139.0
CDKN2C	9068.0
H2AZ1	9026.0
H2AC20	9019.0
UBB	8935.0
JUN	8891.0
KDM6B	8750.0
RNF2	8302.0
MIR24-2	8125.0
TP53	7995.0
E2F1	7979.0
H3C4	7677.0
MDM4	7582.0
MIR24-1	7385.0
H2BC11	7363.0
H2BC5	7354.0
MOV10	7179.0
MAPKAPK2	7010.0
H2BC3	6877.0
CBX4	6802.0
TNIK	6663.0
H4C1	6505.0
BMI1	6356.0
RBBP4	6026.0
CBX2	5858.0
H4C2	5849.0
H2AJ	5832.0
H2AX	5821.0
H4C12	5591.0
MAP4K4	5456.0
H4C8	5375.0
MAPKAPK5	5347.0
MAPK9	4542.0
H3C6	4303.0
AGO1	4301.0
IFNB1	4295.0
TNRC6A	4276.0
H2AZ2	4022.0
MAPK8	3772.0
UBA52	2963.0
H2BC1	2654.0
PHC1	2610.0
H3C10	2553.0
SCMH1	2508.0
MAPKAPK3	2205.0
H2BC10	2021.0
E2F3	1797.0
CBX8	1158.0
MAPK3	901.0
H3C1	733.0
H4C11	725.0
H4C5	654.0
MDM2	617.0
H2BC12	519.0
H3C11	416.0
EZH2	243.0
H4C4	162.0
MAP2K3	0.0
UBC	-323.0
H3C8	-350.0
CDK6	-504.0
MAPK14	-685.0
RING1	-719.0
PHC3	-931.0
AGO4	-1047.0
TNRC6C	-1236.0
CDKN2A	-1239.0
EED	-1311.0
MAP3K5	-1368.0
MAPK1	-1794.0
CDK4	-1880.0
E2F2	-2047.0
TFDP1	-2145.0
AGO3	-2452.0
TFDP2	-2551.0
MAP2K7	-3436.0
MAPK10	-3465.0
MAP2K4	-3501.0
MAPK11	-3633.0
H4C6	-3817.0
MINK1	-4279.0
PHC2	-4284.0
H3C3	-4506.0
H2BC26	-4831.0
SUZ12	-4896.0
CBX6	-5151.0
H2AC18	-5415.5
H2AC19	-5415.5
H4C13	-6090.0
RPS27A	-6484.0
H2BC14	-7223.0
H2BC13	-7559.0
H2AC14	-7938.0
H4C9	-8005.0

---

REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

	1024
set	REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION
setSize	1356
pANOVA	6.27e-07
s.dist	0.0806
p.adjustANOVA	5.15e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
AREG	11469
CHML	11432
NICN1	11269
FCGR3B	11231
RNF181	11185
B3GNT5	11160
CTSZ	11142
AXIN2	11089
RAB42	11070
B3GNT7	10988
USO1	10970
CD52	10962
SYVN1	10855
COMMD3	10850
SATB1	10820
FEM1B	10784
H2AC21	10743
KLHL21	10674
NR4A2	10620
ELOC	10605

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
AREG	11469.0
CHML	11432.0
NICN1	11269.0
FCGR3B	11231.0
RNF181	11185.0
B3GNT5	11160.0
CTSZ	11142.0
AXIN2	11089.0
RAB42	11070.0
B3GNT7	10988.0
USO1	10970.0
CD52	10962.0
SYVN1	10855.0
COMMD3	10850.0
SATB1	10820.0
FEM1B	10784.0
H2AC21	10743.0
KLHL21	10674.0
NR4A2	10620.0
ELOC	10605.0
H2AC4	10558.0
CHST4	10536.0
NR1H2	10523.0
H2BC17	10497.0
MAN1C1	10412.0
ELOB	10398.0
TUBB4B	10395.0
COPS7A	10394.0
ALPG	10378.0
RAB32	10349.0
H2AC15	10342.0
FBXW9	10332.0
RNF135	10325.0
H4C16	10315.0
H2BC15	10314.0
RTN4RL2	10265.0
RAB7A	10227.0
PNPLA2	10208.0
PREB	10184.0
BMP4	10182.0
RAB3D	10165.0
PIGO	10140.0
HRC	10131.0
FBXO2	10103.0
H4C3	10086.0
TFAP2A	10053.0
H2AC6	10052.0
PSMD13	10036.0
PGM3	10026.0
TTLL1	10014.0
RNF7	10011.0
H2BC4	9994.0
H2BC9	9978.5
H2BC6	9964.0
EIF5A	9955.0
H2AC16	9919.0
H2AC8	9917.0
ANKRD9	9909.0
BECN1	9905.0
FBXO44	9891.0
LYPD3	9874.0
POMK	9834.0
PIGY	9815.0
ST6GAL1	9798.0
MGAT2	9794.5
AGBL5	9776.0
UBE2R2	9758.0
BABAM1	9748.0
FSTL3	9721.0
FBXO4	9716.0
SOCS6	9705.0
H2BC21	9693.0
TFAP2B	9688.0
HSP90B1	9674.0
UCHL5	9667.0
NAPA	9652.0
TBC1D20	9648.0
COPZ2	9644.0
ALG8	9625.0
COG1	9624.0
HSPA8	9600.0
CHGB	9591.0
B3GNT9	9586.0
PIAS3	9584.0
TRIM28	9567.0
RAB3A	9566.0
FBXO17	9542.0
RARA	9534.0
TMEM129	9517.0
MVD	9508.0
TRAPPC6A	9489.0
ALPL	9477.0
ANO8	9470.0
POM121	9464.0
BIRC5	9463.0
H2BC8	9455.0
ATXN3	9433.0
TMED3	9428.0
SOCS3	9415.0
RAB14	9410.0
H2AC7	9407.5
H2BC7	9407.5
COMMD2	9404.0
USP33	9384.0
SP3	9372.0
MOGS	9362.0
TRAPPC3	9361.0
TUBB6	9322.0
FBXO27	9308.0
UBXN1	9264.0
SPP1	9241.0
SNX3	9229.0
DPH7	9228.0
BET1	9225.0
RAB43	9224.0
UBE2S	9214.0
P4HB	9206.0
FBXO41	9192.0
FBXL14	9191.0
CNIH1	9135.0
CALR	9075.0
SLC35C1	9066.0
H2AC20	9019.0
CBX5	8962.0
COMMD10	8953.0
EID3	8948.0
RAB1B	8943.0
UBB	8935.0
B3GNT8	8924.0
ULBP2	8907.0
RBBP5	8902.0
ST8SIA6	8853.0
SUMO2	8839.0
RNF144A	8824.0
AURKA	8822.0
SMAD7	8777.0
COMMD7	8739.0
SKIC8	8720.0
PIAS1	8706.0
COPS6	8681.0
PTRH2	8670.0
TGFBR1	8635.0
NPLOC4	8621.0
PSMA6	8609.0
RRAGA	8589.0
LRR1	8583.0
PCNA	8551.0
COPS4	8519.0
B4GALT3	8502.0
DCTN6	8494.0
HIF1A	8488.0
DCAF7	8482.0
TUBA4B	8469.0
DDX5	8460.0
GALNT1	8440.0
SRD5A3	8435.0
UCHL3	8410.0
NUCB1	8409.0
H2AC11	8376.0
ING2	8370.0
DPH5	8352.0
DYNC1LI2	8336.0
USP24	8319.0
RNF2	8302.0
ARSG	8301.0
ABRAXAS1	8286.0
H2AC12	8285.0
FBXO6	8278.0
BARD1	8265.0
IDE	8248.0
NEU3	8246.0
VDAC1	8226.0
H2AC17	8217.0
DPAGT1	8183.0
WDR48	8175.0
PSMC6	8173.0
DHPS	8151.0
RNF123	8106.0
MEN1	8092.0
TP53BP1	8084.0
USP10	8074.0
UBE2N	8070.0
DPH3	8060.0
RAE1	8059.0
NUP58	8047.0
UBE2F	8046.0
FBXL15	8030.0
NRN1	8029.0
TUBA8	8019.0
GALNT6	7996.0
TP53	7995.0
RAD52	7991.0
VDAC2	7965.0
NUP43	7960.0
DCUN1D5	7949.0
RAB38	7883.0
RCN1	7829.0
FBXO40	7828.0
NR5A2	7819.0
INO80C	7806.0
SIAH2	7792.0
NUP35	7791.0
PSME3	7776.0
IL6	7762.0
UBE2G1	7751.0
NUP50	7744.0
FBXW2	7734.0
ABRAXAS2	7730.0
COPG2	7708.0
ETFBKMT	7702.0
NSMCE4A	7696.0
ALG1	7683.0
IFIH1	7675.0
NR1H3	7673.0
DAXX	7619.0
MDM4	7582.0
RFT1	7578.0
ADAMTS8	7572.0
UAP1	7553.0
SQSTM1	7536.0
FBXL16	7516.0
DDB2	7500.0
PALB2	7482.0
TUBB4A	7468.0
CHD3	7459.0
MGAT1	7448.0
SMAD2	7447.0
PIGV	7444.0
UBE2E1	7409.0
UGGT1	7408.0
SPON2	7388.0
TUBA4A	7384.0
PLAUR	7377.0
H2BC11	7363.0
H2BC5	7354.0
KCTD7	7350.0
ASGR1	7344.0
UBXN7	7323.0
FBXO7	7315.0
RAB12	7312.0
FOXK1	7293.0
RAB10	7289.0
NPL	7280.0
B4GALNT2	7271.0
ARF3	7260.0
YOD1	7247.0
LY6K	7217.0
DCAF6	7212.0
GCNT4	7208.0
PLET1	7204.0
GOSR2	7192.0
KDELR3	7180.0
DCTN1	7164.0
NSMCE3	7163.0
NFKBIA	7150.0
SENP8	7131.0
PEX12	7119.0
RXRA	7109.0
MYC	7102.0
RAET1G	7079.0
PIGB	7053.0
LRRC41	7036.0
UFD1	7030.0
PIGS	7007.0
RNF152	6997.0
TRAPPC2L	6990.0
GALNT8	6988.0
SAR1B	6986.0
SPTBN4	6981.0
COPZ1	6980.0
TMEM132A	6969.0
MUC12	6967.0
WRN	6947.0
FBXL8	6943.0
CCN1	6940.0
RAB19	6919.0
DTL	6917.0
ACTR5	6904.0
COMMD8	6888.0
DYNLL2	6886.0
GANAB	6885.0
H2BC3	6877.0
TUBB3	6871.0
RAB5B	6851.0
OTUB2	6847.0
TPGS1	6831.0
CNIH2	6821.0
DCAF4	6813.0
ADAMTSL5	6810.0
RAB4A	6805.0
FEM1C	6803.0
CBX4	6802.0
VDR	6798.0
NSMCE1	6797.0
COPB2	6772.0
COMMD1	6769.0
PSMB3	6752.0
CAND1	6740.0
RAB29	6658.0
PSMD12	6656.0
CDCA8	6641.0
CANX	6634.0
MGAT4B	6626.0
TDG	6613.0
APOL1	6600.0
RAD23B	6579.0
MAT2B	6573.0
ANKRD28	6566.0
GALNT7	6560.0
FUCA2	6556.0
RPN1	6549.0
NUP88	6529.0
FBXW4	6509.0
H4C1	6505.0
STX5	6504.0
RNF20	6494.0
FBXL18	6456.0
MAN2A1	6450.0
PEX13	6444.0
MCFD2	6421.0
DYNC1LI1	6419.0
HLA-A	6401.0
COMMD6	6373.0
SOCS2	6358.0
BMI1	6356.0
FBXL3	6332.0
SEC22C	6324.0
ARSK	6318.0
SEC23A	6281.0
MBD1	6267.0
MUC3A	6243.0
NEDD8	6240.0
RECK	6236.0
VWA1	6231.0
USP25	6224.0
CD55	6202.0
DAD1	6163.0
ARF4	6157.0
TMED9	6139.0
MUC17	6130.0
HIC1	6114.0
ALG2	6107.0
ASB17	6101.0
ZNF131	6100.0
COG5	6058.0
FEM1A	6052.0
PSMB7	6049.0
NUP155	6039.0
SEC24A	6013.0
NTNG2	6006.0
UBE2Q2	5999.0
MUC15	5953.0
LY6E	5926.0
RAB13	5923.0
TGFBR2	5922.0
COG4	5911.0
MAN1A1	5907.0
EEF1A1	5887.0
MGAT5	5880.0
BLM	5877.0
KBTBD8	5876.0
ESR1	5862.0
CBX2	5858.0
H4C2	5849.0
DCAF16	5847.0
HDAC2	5842.0
TAB1	5840.0
KIN	5812.0
CCNF	5786.0
NAGK	5766.0
UBE2G2	5744.0
SEC31A	5730.0
UBA6	5671.0
ASXL1	5643.0
DNMT3A	5642.0
TRAPPC1	5612.0
H4C12	5591.0
CTR9	5587.0
BIRC3	5579.0
STAM2	5561.0
SEL1L	5474.0
MFGE8	5464.0
CDK1	5463.0
PSMC1	5452.0
PIAS4	5432.0
TGOLN2	5420.0
FUOM	5407.0
ACTR10	5394.0
TADA2B	5379.0
H4C8	5375.0
GALNT2	5372.0
TUBB2A	5342.0
KLHL3	5335.0
TUBA3C	5315.0
RAB34	5303.0
GMPPA	5298.0
USP37	5288.0
MATN3	5285.0
MAN1A2	5282.0
HLTF	5267.0
GGCX	5262.0
COMMD9	5255.0
APLP2	5224.0
SEC24B	5187.0
STAMBPL1	5186.0
B4GALT1	5179.0
RAB11A	5178.0
ST8SIA3	5175.0
COPS5	5170.0
CUL3	5141.0
LY6G6D	5138.0
USP28	5117.0
CUL2	5114.0
UBA3	5109.0
NEURL2	5107.0
ST6GALNAC6	5101.0
RAET1L	5090.0
FBXO30	5088.0
PSMD8	5087.0
INO80B	5046.0
SPACA4	5037.0
PPP6C	5034.0
SATB2	5015.0
B3GNT2	5007.0
SBSPON	4985.0
DPH6	4956.0
C1GALT1	4946.0
KLHL42	4929.0
B4GALT6	4925.0
PENK	4913.0
MIA2	4902.0
GMPPB	4898.0
CUL4A	4879.0
ST3GAL6	4870.0
CTSA	4855.0
RAB33B	4851.0
MXRA8	4844.0
FOXK2	4822.0
RAB18	4792.0
APOA1	4789.0
DDX17	4779.0
ALG9	4778.0
CALU	4775.0
ARSJ	4770.0
USP21	4762.0
RAB2B	4748.0
GFPT1	4742.0
NOD1	4737.0
TOP1	4730.0
FBXO32	4726.0
TMED10	4724.0
TMED2	4701.0
FBXO22	4685.0
RAB1A	4671.0
NEU2	4667.0
ASB8	4662.0
NPM1	4661.0
B3GNT3	4660.0
SUMF1	4648.0
PSMB10	4635.0
THY1	4633.0
LMAN1	4618.0
GAN	4615.0
NUS1	4606.0
ERCC8	4598.0
SUDS3	4594.0
YY1	4593.0
NLRP3	4550.0
BTRC	4547.0
CALM1	4537.0
APP	4531.0
PRKCSH	4507.0
UBE2D2	4497.0
MBD6	4469.0
ST6GALNAC4	4445.0
PSMD3	4433.0
CD109	4425.0
HNRNPK	4410.0
DPH2	4395.0
UBE2C	4394.0
CDKN1A	4380.0
GALNT12	4365.0
CCDC8	4349.0
DYNC1H1	4333.0
TRAPPC10	4330.0
AURKB	4328.0
APC	4325.0
DYNC1I1	4315.0
USP16	4281.0
UCHL1	4266.0
RAB27B	4225.0
UBE2D3	4215.0
STT3A	4206.0
EDEM1	4186.0
DCUN1D3	4182.0
DDOST	4181.0
PSMA3	4156.0
CUL1	4104.0
ALG10	4092.0
USP49	4085.0
PROZ	4069.0
GALNT5	4033.0
TRIM4	4018.0
MCRS1	4010.0
RAB2A	4004.0
PTP4A2	3992.0
RAB37	3987.0
ASB6	3951.0
SAFB	3936.0
VCPIP1	3876.0
BST1	3843.0
PSMC2	3840.0
USP13	3824.0
TFAP2C	3823.0
MGAT4A	3785.0
VASH1	3738.0
UBE2H	3736.0
TNFAIP3	3730.0
SENP2	3726.0
ZNF350	3700.0
FSTL1	3692.0
DYNC1I2	3671.0
STC2	3660.0
AGBL2	3641.0
USP4	3640.0
NUP133	3627.0
COPS8	3615.0
SHISA5	3614.0
FOXL2	3613.0
ARSA	3592.0
NUP160	3568.0
COP1	3561.0
USP7	3536.0
COG3	3517.0
MAP3K7	3513.0
RABGGTA	3502.0
GPIHBP1	3475.0
VCP	3474.0
ART4	3461.0
RWDD3	3458.0
PPARA	3456.0
DCAF5	3445.0
POLB	3419.0
IGFBP4	3406.0
MUL1	3367.0
DNAJC3	3357.0
FBXL19	3346.0
NEU4	3314.0
NCOR2	3299.0
FBXW11	3290.0
NUP214	3289.0
KEAP1	3287.0
UBA2	3213.0
SPTAN1	3207.0
PAF1	3202.0
NOTUM	3193.0
RAB8B	3184.0
CSF1	3150.0
DCTN2	3142.0
NANS	3114.0
TADA3	3112.0
PSMC5	3099.0
HDAC1	3086.0
CP	3079.0
OTUD7A	3066.0
IKBKE	3039.0
DDB1	3033.0
UIMC1	3022.0
ARRB1	3002.0
NUP188	2995.0
FBXL5	2993.0
UBA52	2963.0
PSMB1	2960.0
EDEM3	2945.0
TNIP3	2935.0
FBXL4	2915.0
PIGZ	2903.0
FBXO15	2898.0
XPC	2874.0
NSMCE2	2873.0
ATXN7	2871.0
COPS2	2870.0
GNE	2860.0
NRIP1	2854.0
UBE2W	2838.0
TTL	2817.0
IGFBP3	2803.0
SKP2	2789.0
HDAC7	2761.0
MELTF	2714.0
CD59	2711.0
ASB3	2693.0
SVBP	2691.0
STX17	2655.0
H2BC1	2654.0
ASB14	2653.0
VGF	2631.0
THRA	2630.0
TGFA	2620.0
LGALS1	2616.0
PHC1	2610.0
UBE2K	2605.0
PPP6R3	2603.0
PSMB2	2596.0
STAG1	2592.0
CREBBP	2578.0
DCAF17	2574.0
SMAD1	2562.0
SHPRH	2540.0
EEF1AKMT2	2525.0
SCMH1	2508.0
AGTPBP1	2505.0
PSMA1	2497.0
DOHH	2483.0
SIN3A	2466.0
RAB23	2456.0
PSMB5	2455.0
PSMD2	2443.0
B4GALT2	2436.0
USP22	2432.0
PSMA7	2417.0
PTEN	2393.0
TRAF3	2359.0
BABAM2	2351.0
DYNLL1	2349.0
DOLPP1	2339.0
B3GALNT2	2326.0
PEX5	2316.0
ST8SIA1	2311.0
SEH1L	2309.0
ST8SIA5	2282.0
PSMB4	2281.0
USP3	2267.0
USP15	2252.0
ALG11	2249.0
KBTBD6	2248.0
KLHL5	2243.0
PIGT	2236.0
SP100	2232.0
ASB13	2183.0
WAC	2148.0
SEC22B	2144.0
ADAMTS17	2120.0
POMGNT1	2114.0
ETFB	2097.0
THBS1	2088.0
FBXL22	2070.0
METTL21A	2056.0
PSMD4	2042.0
H2BC10	2021.0
GALNT4	2015.0
RHOT1	2005.0
SPSB2	2004.0
COG7	1981.0
ST8SIA4	1974.0
TRRAP	1966.0
NUB1	1963.0
NR1I2	1961.0
RAB15	1924.0
USP47	1923.0
RPA1	1885.0
SMURF2	1884.0
RAB8A	1869.0
POMGNT2	1862.0
PPP6R1	1849.0
TPGS2	1844.0
USP18	1827.0
SENP5	1799.0
PIGL	1763.0
PPARG	1757.0
DCTN5	1751.0
SPSB1	1741.0
TFPT	1719.0
CKAP4	1711.0
B3GLCT	1691.0
SELENOS	1689.0
PIGM	1675.0
USP42	1658.0
DDA1	1636.0
PPARGC1A	1629.0
ICMT	1615.0
PSME1	1571.0
PRMT3	1559.0
MRTFA	1554.0
SKP1	1543.0
ACTB	1540.0
FCSK	1537.0
NUP107	1453.0
LEO1	1429.0
HDAC4	1418.0
ST3GAL1	1412.0
GALNT10	1394.0
NAPG	1386.0
USP5	1379.0
CYLD	1377.0
UBE2M	1374.0
MLEC	1373.0
METTL22	1320.0
RPS2	1277.0
NFE2L2	1267.0
SENP1	1260.0
PSME2	1245.0
RAB5C	1228.0
RNF40	1227.0
RNF5	1224.0
RUVBL1	1222.0
PSMA2	1218.0
FN3K	1213.0
RNF146	1184.0
PSMB6	1163.0
CBX8	1158.0
SMAD3	1155.0
PRSS23	1151.0
POM121C	1147.0
PRSS21	1129.0
TMED7	1126.0
YKT6	1119.0
AXIN1	1098.0
TRAF6	1095.0
NUP62	1081.0
LMAN2	1074.0
RAB22A	1054.0
TUBB1	1042.0
FBXW5	1016.0
EEF2KMT	1014.0
TRAPPC6B	997.0
NUP85	973.0
TUBAL3	971.0
NGLY1	961.0
PIGP	940.0
TPST1	882.0
LHB	878.0
ARFGAP3	870.0
PIGK	856.0
TOPORS	840.0
DNMT1	817.0
KAT2B	811.0
PIGC	797.0
OTUB1	793.0
EP300	777.0
EPAS1	774.0
SLC17A5	752.0
CCNA1	745.0
INO80	736.0
PML	732.0
DCUN1D1	731.0
NFKB2	730.0
EDEM2	729.0
H4C11	725.0
SCG3	695.0
OTULIN	687.0
USP44	668.0
H4C5	654.0
GALNT16	637.0
FBXO10	622.0
MDM2	617.0
CSNK1D	610.0
B4GALT4	607.0
DPH1	598.0
NCOA1	595.0
USP2	577.0
PDIA3	575.0
B3GNTL1	574.0
RELA	572.0
ARSI	560.0
UBE2D1	557.0
NANP	546.0
H2BC12	519.0
ACTR1A	495.0
VNN1	486.0
ZBTB16	437.0
COPS7B	436.0
NCOA2	417.0
GOSR1	409.0
NR3C1	406.0
OPCML	370.0
SEC24D	369.0
SEM1	329.0
TAF10	308.0
GOLM1	296.0
VDAC3	294.0
TUBA1B	276.0
VCAN	275.0
GRIA1	262.0
ST6GALNAC1	237.0
CCP110	211.0
AAAS	206.0
SMAD4	194.0
UMOD	173.0
H4C4	162.0
PIGU	159.0
AGBL3	151.0
KLHL22	140.0
ALG5	130.0
UBE2B	105.0
SPTBN1	93.0
RAD23A	71.0
FBXL12	68.0
DOLK	48.0
BET1L	45.0
CPM	37.0
MGAT4C	28.0
RAD21	23.0
B4GALT5	14.0
DERL2	-18.0
DAG1	-41.0
KLHL25	-49.0
PSMB8	-53.0
VNN2	-60.0
RAB24	-74.0
CISH	-82.0
NUP153	-100.0
DHDDS	-120.0
STAMBP	-146.0
USP8	-161.0
SPSB3	-162.0
SPON1	-210.0
ARSB	-231.0
BRCA1	-237.0
KLHL2	-247.0
TRAPPC4	-249.0
SEC23IP	-300.0
TRAPPC5	-312.0
UBC	-323.0
VHL	-326.0
ADAMTS20	-329.0
TTLL3	-348.0
XRCC4	-355.0
ADAMTS9	-357.0
TULP4	-369.0
PSMD5	-411.0
SMC5	-453.0
ADAMTSL4	-463.0
PGR	-473.0
CAPZB	-478.0
CUL7	-486.0
ALG6	-511.0
CHST8	-522.0
FBXO9	-529.0
PSMA5	-534.0
SAE1	-571.0
CUL5	-608.0
RABGGTB	-609.0
DCAF8	-630.0
ADAMTS12	-636.0
ST3GAL3	-645.0
SEC24C	-674.0
OS9	-675.0
BCL10	-688.0
TNKS	-689.0
GALNT11	-693.0
RING1	-719.0
PIGW	-726.0
PSMB9	-734.0
GNPNAT1	-736.0
RAB26	-740.0
PSME4	-771.0
ARRB2	-777.0
RAB3C	-785.0
PSMD11	-805.0
DCTN4	-808.0
IGFBP5	-819.0
NUP98	-843.0
LYPD6B	-844.0
PARP1	-847.0
RAB27A	-930.0
PHC3	-931.0
COMMD4	-934.0
ADAMTS10	-935.0
MPDU1	-963.0
TF	-972.0
TRIM13	-976.0
RAB30	-991.0
PDIA6	-995.0
KDELR1	-1021.0
AMFR	-1027.0
GOLGB1	-1051.0
MBTPS1	-1052.0
COPB1	-1058.0
ARF5	-1061.0
TRAF2	-1113.0
WSB2	-1130.0
FURIN	-1134.0
CEACAM5	-1162.0
FUCA1	-1180.0
RNF139	-1192.0
ADAMTSL1	-1221.0
MAVS	-1222.0
CDKN2A	-1239.0
MDC1	-1241.0
COPS3	-1252.0
USP34	-1295.0
UBE2E3	-1308.0
ST6GALNAC2	-1315.0
CDH2	-1317.0
NUP205	-1359.0
PIGH	-1362.0
TGFB1	-1410.0
CAPZA1	-1417.0
ST6GALNAC5	-1420.0
GALNT17	-1424.0
ANK3	-1436.0
RAB40B	-1466.0
PARK7	-1494.0
VCPKMT	-1506.0
KLHL11	-1521.0
TRIM27	-1534.0
ACTL6A	-1547.0
RHOA	-1560.0
ADRB2	-1561.0
POMT1	-1586.0
CAMKMT	-1591.0
LYPD1	-1601.0
WDTC1	-1633.0
PCGF2	-1658.0
BTBD1	-1667.0
ADAMTS1	-1669.0
RNF185	-1671.0
VASH2	-1679.0
MARCHF6	-1711.0
TTLL10	-1714.0
NAE1	-1718.0
CNTN5	-1723.0
H2AC1	-1730.0
RPN2	-1767.0
GFPT2	-1776.0
USP12	-1802.0
EEF1AKMT1	-1827.0
LTBP1	-1831.0
TECTA	-1844.0
ASB16	-1846.0
HIPK2	-1861.0
RAB4B	-1893.0
PSMD7	-1937.0
DCAF11	-1951.0
TTLL13	-1959.0
PEX2	-1960.0
QSOX1	-1962.0
ADAMTS18	-1971.0
INO80E	-1984.0
SDC2	-2040.0
LSAMP	-2042.0
FBXW8	-2052.0
CDC73	-2117.0
DNMT3B	-2120.0
FBXW7	-2124.0
KLHL9	-2151.0
GATA3	-2179.0
PEX14	-2192.0
ACTR8	-2201.0
FBXO11	-2211.0
RNF168	-2213.0
H2AC13	-2215.0
FN3KRP	-2245.0
ST3GAL2	-2247.0
MAN1B1	-2256.0
KCTD6	-2265.0
TTLL6	-2287.0
RAB6A	-2290.0
TNIP2	-2298.0
FBXL13	-2328.0
NUP210	-2340.0
USP14	-2347.0
DCAF13	-2351.0
JOSD2	-2378.0
WDR20	-2382.0
DCUN1D4	-2387.0
PRSS41	-2398.0
PRKN	-2446.0
TRIM25	-2471.0
BAP1	-2477.0
TOP2A	-2478.0
CAPZA2	-2480.0
ARFGAP2	-2544.0
ASXL2	-2556.0
SCFD1	-2585.0
GALNT13	-2645.0
LARGE2	-2658.0
F7	-2662.0
SUMO3	-2666.0
LYPD5	-2669.0
RORA	-2672.0
FKBP8	-2676.0
TTLL9	-2689.0
ADAMTS3	-2693.0
DERL1	-2701.0
SCG2	-2768.0
UHRF2	-2779.0
USP20	-2786.0
TTLL11	-2874.0
USP19	-2879.0
PIGF	-2905.0
PSMD9	-2906.0
ALG12	-2908.0
TTLL7	-2942.0
GALNT3	-2966.0
TOMM70	-3021.0
SUMO1	-3031.0
NR3C2	-3037.0
SEC16A	-3048.0
KTN1	-3050.0
RAD18	-3084.0
RAB39A	-3091.0
MUC20	-3102.0
DNAJC24	-3106.0
CNIH3	-3111.0
FBXO31	-3115.0
GPS1	-3122.0
SEC22A	-3129.0
CDC20	-3146.0
FBXW12	-3218.0
KDELR2	-3236.0
LY6H	-3267.0
TOMM20	-3272.0
GALNTL6	-3313.0
ARCN1	-3335.0
ADAMTS5	-3348.0
RAB5A	-3349.0
SEMA5A	-3377.0
GMDS	-3419.0
LYPD4	-3441.0
DPM2	-3452.0
NR5A1	-3458.0
PMM2	-3477.0
MIA3	-3536.0
FGF23	-3565.0
TUBA1A	-3578.0
NFRKB	-3591.0
GFUS	-3592.0
GPLD1	-3604.0
ADAMTS7	-3611.0
THSD7B	-3613.0
RTN4RL1	-3651.0
ASB1	-3654.0
MANEA	-3662.0
PIGX	-3680.0
CTBP1	-3683.0
MUC4	-3695.0
OTUD7B	-3702.0
UBE2L3	-3724.0
NTNG1	-3741.0
PIGN	-3749.0
MUCL1	-3759.0
BIRC2	-3812.0
H4C6	-3817.0
TUBA3E	-3827.0
TPST2	-3829.0
MUC6	-3850.0
UBE2T	-3864.0
GP2	-3875.0
RAB21	-3880.0
ADRM1	-3884.0
GPAA1	-3896.0
ADAM10	-3906.0
THSD4	-3907.0
WDR5	-3915.0
SEMA5B	-3938.0
FBXL7	-3947.0
NOP58	-3959.0
LRRC49	-3960.0
RAB3B	-3989.0
NTM	-3990.0
PRKDC	-3998.0
GALNT9	-4010.0
L3MBTL2	-4017.0
CNTN4	-4026.0
FBXL20	-4043.0
WFS1	-4072.0
FAM20A	-4084.0
TUBA1C	-4095.0
RAB40C	-4096.0
SPTB	-4098.0
ANK2	-4115.0
FBN1	-4132.0
USP48	-4134.0
PIAS2	-4146.0
PIGG	-4156.0
TNIP1	-4180.0
COG2	-4181.0
ST3GAL5	-4186.0
RNF103	-4270.0
DPM1	-4272.0
PHC2	-4284.0
RAB36	-4328.0
CCNA2	-4363.0
ANK1	-4391.0
INO80D	-4392.0
PCSK9	-4400.0
DCUN1D2	-4428.0
CMAS	-4431.0
LAMB2	-4434.0
APOE	-4456.0
KAT2A	-4470.0
TRAPPC9	-4472.0
ADAMTS16	-4477.0
PSMC3	-4492.0
MAN2A2	-4515.0
APOB	-4556.0
TNKS2	-4557.0
NEU1	-4560.0
ART3	-4586.0
FBXO21	-4616.0
MUC5B	-4661.0
PUM2	-4667.0
C3	-4674.0
B3GNT4	-4685.0
HNRNPC	-4690.0
ASB7	-4692.0
NDC1	-4745.0
NR2C1	-4800.0
SUMF2	-4801.0
H2BC26	-4831.0
NOD2	-4838.0
LMAN2L	-4855.0
C4A	-4877.5
TUBA3D	-4880.0
KNG1	-4884.0
SUZ12	-4896.0
STAM	-4909.0
OTOA	-4924.0
UBE2V2	-4928.0
ADAMTS15	-4937.0
LMO7	-4958.0
ALG14	-5057.0
NAPB	-5072.0
ST6GAL2	-5073.0
MUC1	-5074.0
ST3GAL4	-5084.0
COG6	-5136.0
CDC25A	-5146.0
UBE2Z	-5148.0
NUP42	-5150.0
TTLL5	-5184.0
COPA	-5223.0
H2AC25	-5226.0
TOP2B	-5228.0
KLHL20	-5233.0
RANBP2	-5265.0
GBF1	-5275.0
PSMD14	-5297.0
SERPINC1	-5299.0
NUP37	-5314.0
USP30	-5325.0
OTUD3	-5328.0
MDGA2	-5330.0
ADAMTSL2	-5367.0
RIGI	-5371.0
NSF	-5387.0
HERC2	-5391.0
TTLL4	-5408.0
H2AC18	-5415.5
H2AC19	-5415.5
POFUT2	-5423.0
NEGR1	-5430.0
CLSPN	-5454.0
THSD1	-5476.0
RIPK2	-5497.0
FPGT	-5502.0
SMC6	-5506.0
PSMD1	-5508.0
POMT2	-5511.0
MUC7	-5529.0
ST6GALNAC3	-5531.0
NRN1L	-5551.0
TMEM115	-5575.0
ADAMTS19	-5607.0
JOSD1	-5615.0
ST8SIA2	-5616.0
PSMD6	-5633.0
PSMF1	-5638.0
KBTBD7	-5701.0
MPI	-5707.0
NUP93	-5736.0
CTSC	-5762.0
PROC	-5764.0
SOCS5	-5782.0
MBD5	-5810.0
RANGAP1	-5823.0
RAB31	-5851.0
COPG1	-5885.0
PEX10	-5886.0
IGFBP7	-5937.0
THBS2	-5944.0
LAMB1	-5957.0
GCNT1	-6053.0
FUT8	-6062.0
GOLGA2	-6063.0
TFG	-6080.0
H4C13	-6090.0
IGFBP1	-6107.0
ASB2	-6127.0
NUP54	-6131.0
UBE2J2	-6144.0
LAMC1	-6158.0
SMC3	-6169.0
ZRANB1	-6178.0
COMMD5	-6184.0
PIGQ	-6186.0
ENGASE	-6189.0
RIPK1	-6194.0
MTA1	-6195.0
TUSC3	-6198.0
SERPINA1	-6199.0
NUDT14	-6221.0
SPP2	-6248.0
TECTB	-6310.0
CUL9	-6337.0
AGBL1	-6379.0
THSD7A	-6412.0
FN1	-6453.0
RAB11B	-6476.0
RPS27A	-6484.0
GCNT3	-6495.0
LYPD8	-6513.0
F2	-6517.0
CNTN3	-6571.0
LY6G6C	-6585.0
PSMA8	-6587.0
ASB15	-6611.0
PSMC4	-6643.0
RAB20	-6684.0
ASB18	-6738.0
COG8	-6744.0
EIF5A2	-6792.0
SEC13	-6814.0
GORASP1	-6885.0
BPIFB2	-6887.0
RCE1	-6895.0
RBX1	-6897.0
CHST10	-6927.0
TNC	-6945.0
RAB6B	-6963.0
MUC16	-7000.0
UBD	-7075.0
AMDHD2	-7111.0
DCTN3	-7114.0
INS	-7133.0
A4GNT	-7165.0
MITF	-7171.0
H2BC14	-7223.0
PSMA4	-7243.0
ASB4	-7276.0
SPTBN5	-7285.0
ADAMTS2	-7308.0
SPSB4	-7316.0
TUBB2B	-7326.0
DCAF10	-7328.0
MDGA1	-7336.0
ADAMTS6	-7371.0
IL33	-7391.0
AMBN	-7406.0
MUC21	-7407.0
GALNTL5	-7462.0
ASB5	-7467.0
LARGE1	-7471.0
WSB1	-7487.0
ALG3	-7535.0
AGBL4	-7554.0
H2BC13	-7559.0
UBE2I	-7598.0
COL7A1	-7631.0
OBSL1	-7648.0
PRND	-7671.0
ADAMTS4	-7693.0
DMP1	-7719.0
HGS	-7732.0
SPARCL1	-7745.0
SERPINA10	-7754.0
KLHL41	-7761.0
FAM20C	-7762.0
RAB35	-7770.0
COPE	-7800.0
ARF1	-7806.0
GCNT7	-7825.0
UGGT2	-7826.0
SLC35A1	-7848.0
IZUMO1R	-7914.0
H2AC14	-7938.0
DPP3	-7945.0
ALG10B	-7947.0
FOLR2	-7973.0
SSPOP	-7986.0
H4C9	-8005.0
KDM1B	-8010.0
MYSM1	-8014.0
B3GNT6	-8029.0
SERPIND1	-8102.0
CDC34	-8133.0
EEF2	-8152.0
THRB	-8154.0
APOA2	-8190.0
RTF1	-8219.0
PMM1	-8233.0
GLB1	-8246.0
F5	-8257.0
TPR	-8306.0
GALNT14	-8310.0
INCENP	-8317.0
EVA1A	-8343.0
AMTN	-8405.0
LMAN1L	-8420.0
HIF3A	-8456.0
GALNT18	-8475.0
TTLL8	-8486.0
ARFGAP1	-8509.0
LYPD2	-8600.0
MGAT3	-8654.0
DPM3	-8675.0
PSCA	-8676.0
ASGR2	-8691.0
PGAP1	-8705.0
ASB10	-8729.0
SPTBN2	-8740.0
AFP	-8779.0
SPRN	-8787.0
TUBB8	-8794.0
ADAMTSL3	-8855.0
ALB	-8941.0
SEC16B	-8963.0
ITIH2	-8971.0
CFTR	-8973.0
RAB44	-8979.0
FBXW10	-9010.0
TEX101	-9087.0
NR1H4	-9094.0
ADAMTS13	-9101.0
F10	-9133.0
CAPZA3	-9138.0
MEPE	-9143.0
CST3	-9147.0
ENAM	-9148.0
FGA	-9164.0
RAB25	-9172.0
BTBD6	-9173.0
FOLR1	-9239.0
LY6D	-9244.0
TTLL12	-9256.0
MUC5AC	-9322.0
ALPI	-9392.0
PROS1	-9568.0
APOA5	-9584.0
ADAMTS14	-9585.0
SPTA1	-9592.0
RAB17	-9620.0
CGA	-9627.0
FUT3	-9683.0
PSMB11	-9711.0
MSLN	-9825.0
GALNT15	-9882.0
FGG	-9928.0
AHSG	-9976.0
BGLAP	-10015.0
MUC13	-10051.0
TTLL2	-10155.0
B4GAT1	-10228.0
CEACAM7	-10252.0

---

REACTOME_ASPIRIN_ADME

REACTOME_ASPIRIN_ADME

	1595
set	REACTOME_ASPIRIN_ADME
setSize	42
pANOVA	7.2e-07
s.dist	-0.442
p.adjustANOVA	5.63e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CYP2C8	-10061
SLC22A7	-9953
UGT2B7	-9449
ACSM4	-9189
GLYATL3	-9132
CES1	-8976
ALB	-8941
UGT2B11	-8383
GLYATL1	-8251
GLYATL2	-8185
GLYAT	-8124
UGT1A6	-7901
CYP2C9	-7715
UGT2A1	-7444
UGT2A3	-7334
SLCO2B1	-7252
ABCC2	-6901
UGT1A7	-6843
CYP2E1	-6828
UGT1A9	-6775

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CYP2C8	-10061
SLC22A7	-9953
UGT2B7	-9449
ACSM4	-9189
GLYATL3	-9132
CES1	-8976
ALB	-8941
UGT2B11	-8383
GLYATL1	-8251
GLYATL2	-8185
GLYAT	-8124
UGT1A6	-7901
CYP2C9	-7715
UGT2A1	-7444
UGT2A3	-7334
SLCO2B1	-7252
ABCC2	-6901
UGT1A7	-6843
CYP2E1	-6828
UGT1A9	-6775
UGT2A2	-6376
UGT1A3	-6302
UGT1A4	-6279
UGT1A5	-6057
ACSM5	-5922
CYP3A4	-5840
UGT1A8	-5809
UGT1A1	-5771
CES2	-4267
UGT2B17	-4254
BSG	-3999
UGT3A1	-1059
ABCC3	-462
UGT2B4	-37
CYP2C19	15
ACSM2B	208
BCHE	2586
UGT3A2	3832
CYP2D6	7274
SLC16A1	8472
UGT2B15	9203
ACSM2A	11298

---

REACTOME_TRANSLATION

REACTOME_TRANSLATION

	1152
set	REACTOME_TRANSLATION
setSize	278
pANOVA	8.5e-07
s.dist	0.172
p.adjustANOVA	6.34e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MRPL45	10978.0
MRPS18C	10814.0
CHCHD1	10678.0
GADD45GIP1	10537.0
MRPL11	10509.0
RPL26	10476.0
MRPL16	10450.0
RPL10A	10291.0
MRPL34	10264.0
RPS16	10188.0
NARS1	10021.0
EIF2B2	9991.0
RPL39L	9799.0
RPL36AL	9794.5
RPL29	9738.0
MTIF2	9659.0
MRPL10	9595.0
YARS1	9563.0
PPA1	9435.0
MRPS18B	9367.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MRPL45	10978.0
MRPS18C	10814.0
CHCHD1	10678.0
GADD45GIP1	10537.0
MRPL11	10509.0
RPL26	10476.0
MRPL16	10450.0
RPL10A	10291.0
MRPL34	10264.0
RPS16	10188.0
NARS1	10021.0
EIF2B2	9991.0
RPL39L	9799.0
RPL36AL	9794.5
RPL29	9738.0
MTIF2	9659.0
MRPL10	9595.0
YARS1	9563.0
PPA1	9435.0
MRPS18B	9367.0
MRPL27	9291.0
SEC11A	8900.0
MRPL47	8887.0
RPL27	8846.0
RPS28	8785.0
EIF3I	8753.0
MRPL36	8736.0
MRPS16	8696.0
SRP54	8611.0
MRPL44	8591.0
MRPL3	8584.0
MRPS10	8518.0
EIF2B1	8493.0
MRPL33	8459.0
RPL37A	8438.0
MTFMT	8431.0
RPL26L1	8414.0
MRPL39	8364.0
RPS19	8176.0
PTCD3	8160.0
MRPL54	8017.0
RPL15	7977.0
RPL6	7932.0
DARS1	7920.0
RPL34	7790.0
RPS3A	7611.0
RPS27L	7580.0
EIF3F	7518.0
RPL23	7379.0
EARS2	7338.0
RPL35A	7327.0
SPCS3	7307.0
MARS2	7241.0
MRPL2	7187.0
RPL28	7186.0
SPCS1	7120.0
MRPS9	7110.0
RPL11	7034.0
MRPS18A	7002.0
MRPL37	6960.0
MRPS11	6958.0
PARS2	6912.0
MRPL52	6901.0
RPS15A	6793.0
EIF3J	6724.0
SEC61B	6637.0
RPL41	6591.0
RPLP1	6550.0
RPN1	6549.0
MRPS24	6513.0
MRPL24	6508.0
FAU	6502.0
RPL24	6382.0
EIF5	6355.0
MRPS31	6334.0
MRPS15	6279.0
RPS5	6275.0
EEF1E1	6274.0
OXA1L	6190.0
VARS2	6166.0
N6AMT1	6129.0
EIF4E	6127.0
LARS1	6045.0
EEF1A1	5887.0
RPL7	5777.0
IARS2	5651.0
EEF1A2	5564.0
RPS29	5507.0
RPL36	5403.0
EPRS1	5355.0
RPS11	5323.0
MRPL22	5221.0
WARS1	5152.0
EIF3K	5139.0
MRPL50	5058.0
EIF3A	5021.0
RPS20	4993.0
RPS10	4983.0
MTIF3	4982.0
MRPL58	4958.0
ERAL1	4939.0
SEC61G	4933.0
RPS9	4917.0
SRP9	4916.0
SSR3	4873.0
RPL37	4854.0
RPL27A	4853.0
TARS1	4829.0
EIF4B	4729.0
SPCS2	4693.0
FARS2	4684.0
EEF1D	4652.0
MRPL4	4610.0
MRPS27	4570.0
MRPS28	4503.0
MRPS12	4475.0
RPL18	4341.0
RPS23	4307.0
EIF5B	4288.0
RPL9	4204.0
DDOST	4181.0
TRAM1	4172.0
EIF2B3	4115.0
MRPL21	4014.0
GARS1	3949.0
MRPL49	3935.0
RPS21	3934.0
CARS2	3864.0
TRMT112	3862.0
YARS2	3710.0
MRPL57	3637.0
MRPL14	3619.0
RPS12	3607.0
MRPL46	3569.0
RPL17	3492.0
TUFM	3479.0
MRPL1	3288.0
MRPS33	3205.0
EEF1G	3120.0
MRPS7	3029.0
EIF3M	2986.0
SSR1	2973.0
UBA52	2963.0
RPL13	2937.0
RPSA	2801.0
MRPL28	2786.0
MRPS6	2732.0
EIF2B4	2696.0
MRPL9	2613.0
DARS2	2600.0
APEH	2598.0
MRPL42	2561.0
GSPT1	2524.0
MTRF1L	2446.0
MRPL20	2366.0
IARS1	2305.0
MRPL17	2068.0
HARS1	1968.0
MRPL41	1936.0
RPL38	1935.0
MRRF	1931.0
RPL19	1906.0
AARS1	1788.0
SRP68	1771.0
LARS2	1703.0
MRPS34	1643.0
MRPL53	1343.0
RPS7	1305.0
RPS2	1277.0
SRP72	1145.0
MRPL15	1111.0
NARS2	1005.0
VARS1	986.0
MRPL19	984.0
RPS14	948.0
EIF3H	935.0
SARS2	719.0
EIF4EBP1	710.0
RPS24	630.0
DAP3	597.0
RPS13	553.0
MRPL18	503.0
KARS1	483.0
EIF4H	448.0
PPA2	397.0
CARS1	95.0
RPL21	76.0
RPS3	69.0
FARSA	-21.0
RPL4	-172.0
MRPS21	-217.0
SEC61A1	-335.0
SRP14	-360.0
RPS27	-651.0
RPL22	-684.0
EIF3D	-690.0
SRPRB	-731.0
MRPL51	-786.0
SRPRA	-937.0
MRPS26	-1042.0
FARSB	-1050.0
AURKAIP1	-1054.0
HARS2	-1098.0
MRPL32	-1112.0
MRPL30	-1199.0
RPS18	-1287.0
RPS8	-1337.0
ETF1	-1431.0
EIF3B	-1467.0
MRPS30	-1569.0
MRPS23	-1759.0
RPL35	-1762.0
RPN2	-1767.0
MARS1	-1841.0
EIF3G	-1916.0
TSFM	-1979.0
RPL32	-2032.0
MRPL12	-2038.0
EIF4G1	-2231.0
MRPL13	-2266.0
RPL18A	-2322.0
MRPS22	-2454.0
MRPL40	-2493.0
RARS2	-2498.0
RPLP0	-2534.0
SRP19	-2541.0
EIF2B5	-2570.0
AIMP1	-2738.0
RPS25	-2921.0
MRPL55	-3076.0
RPS6	-3203.0
GFM2	-3229.0
WARS2	-3337.0
MRPL23	-3363.0
RPL22L1	-3364.0
MRPS35	-3424.0
RARS1	-3603.0
RPLP2	-3777.0
MRPS2	-3934.0
EIF2S1	-3972.0
RPL14	-3997.0
SSR2	-4059.0
RPL12	-4199.0
MRPS17	-4320.0
RPL30	-4351.0
RPS15	-4386.0
MRPS25	-4414.0
RPL31	-4613.0
GFM1	-4716.0
MRPL48	-4808.0
MRPL43	-4895.0
MRPL35	-5752.0
EIF4A2	-6222.0
RPS26	-6416.0
MRPS14	-6452.0
RPS27A	-6484.0
SEC11C	-6539.0
MRPS5	-6848.0
EIF4A1	-6870.0
TARS2	-6892.0
RPL3L	-6960.0
PABPC1	-7335.0
RPL8	-7369.0
RPL23A	-7390.0
AARS2	-7439.0
RPL5	-7510.0
EEF1B2	-7808.0
RPL3	-7876.0
EIF3E	-8020.0
MRPL38	-8030.0
EIF2S2	-8052.0
EIF3L	-8079.0
EEF2	-8152.0
RPL10L	-8234.0
SEC61A2	-8415.0
RPL13A	-9002.5
AIMP2	-9202.0
RPL7A	-9413.0

---

REACTOME_DNA_REPAIR

REACTOME_DNA_REPAIR

	1168
set	REACTOME_DNA_REPAIR
setSize	321
pANOVA	1.04e-06
s.dist	0.159
p.adjustANOVA	7.13e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
UBA7	11003.0
XPA	10686.0
H2AC4	10558.0
H2BC17	10497.0
COPS7A	10394.0
H4C16	10315.0
H2BC15	10314.0
POLE2	10284.0
MPG	10193.0
H4C3	10086.0
H2AC6	10052.0
H2BC4	9994.0
H2BC9	9978.5
H2BC6	9964.0
H2AC8	9917.0
BABAM1	9748.0
TIMELESS	9697.0
H2BC21	9693.0
BRCA2	9605.0
PIAS3	9584.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
UBA7	11003.0
XPA	10686.0
H2AC4	10558.0
H2BC17	10497.0
COPS7A	10394.0
H4C16	10315.0
H2BC15	10314.0
POLE2	10284.0
MPG	10193.0
H4C3	10086.0
H2AC6	10052.0
H2BC4	9994.0
H2BC9	9978.5
H2BC6	9964.0
H2AC8	9917.0
BABAM1	9748.0
TIMELESS	9697.0
H2BC21	9693.0
BRCA2	9605.0
PIAS3	9584.0
SIRT6	9456.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
POLR2C	9358.0
UBXN1	9264.0
XRCC6	9095.0
MUS81	9057.0
H2AZ1	9026.0
H2AC20	9019.0
UBB	8935.0
RNF8	8912.0
CHD1L	8895.0
SUMO2	8839.0
POLE4	8745.0
PIAS1	8706.0
COPS6	8681.0
ISY1	8665.0
NPLOC4	8621.0
LIG3	8613.0
PCNA	8551.0
COPS4	8519.0
POLR2G	8490.0
DCLRE1C	8369.0
ABRAXAS1	8286.0
BARD1	8265.0
POLE3	8257.0
WDR48	8175.0
CCNH	8147.0
EME1	8101.0
TP53BP1	8084.0
USP10	8074.0
UBE2N	8070.0
CENPS	8051.0
TP53	7995.0
RAD52	7991.0
OGG1	7957.0
POLD4	7923.0
DCLRE1A	7816.0
RPA3	7810.0
INO80C	7806.0
RAD51AP1	7731.0
RPA2	7679.0
SLX4	7566.0
DDB2	7500.0
PALB2	7482.0
RAD9B	7481.0
H2BC11	7363.0
H2BC5	7354.0
PNKP	7256.0
RFC4	7122.0
UFD1	7030.0
POLD1	7018.0
WRN	6947.0
DTL	6917.0
ACTR5	6904.0
ZNF830	6897.0
H2BC3	6877.0
FAAP24	6767.0
CDK7	6742.0
POLK	6717.0
TDG	6613.0
RAD23B	6579.0
RBBP8	6518.0
H4C1	6505.0
EYA3	6495.0
EXO1	6320.0
FANCF	6225.0
TDP2	6201.0
POLD2	6199.0
DCLRE1B	6171.0
RMI1	6032.0
APBB1	5972.0
MBD4	5956.0
POLR2I	5881.0
BLM	5877.0
H4C2	5849.0
H2AJ	5832.0
H2AX	5821.0
XRCC2	5800.0
KAT5	5792.0
PARP2	5768.0
RFC5	5739.0
POLQ	5714.0
RNF111	5654.0
H4C12	5591.0
FANCE	5567.0
PIAS4	5432.0
H4C8	5375.0
COPS5	5170.0
INO80B	5046.0
GTF2H5	5045.0
ERCC5	5023.0
POT1	5008.0
ATM	4998.0
CUL4A	4879.0
NEIL1	4801.0
ERCC8	4598.0
YY1	4593.0
BAZ1B	4400.0
TCEA1	4339.0
RAD51D	4279.0
ASCC3	4198.0
FANCD2	4136.0
H2AZ2	4022.0
RHNO1	4015.0
MCRS1	4010.0
SMARCA5	3945.0
ASCC1	3795.0
MAPK8	3772.0
RAD17	3742.0
ATR	3678.0
COPS8	3615.0
USP7	3536.0
ACD	3521.5
ERCC1	3506.0
VCP	3474.0
NEIL3	3423.0
POLB	3419.0
POLR2K	3416.0
UNG	3329.0
SPRTN	3217.0
MSH2	3165.0
PCLAF	3084.0
DDB1	3033.0
UIMC1	3022.0
CDK2	2988.0
UBA52	2963.0
MSH6	2905.0
ISG15	2875.0
XPC	2874.0
COPS2	2870.0
FANCM	2849.0
DNA2	2805.0
POLR2B	2795.0
H2BC1	2654.0
ABL1	2597.0
CHEK1	2585.0
NTHL1	2530.0
RAD51	2407.0
APEX1	2373.0
BABAM2	2351.0
KPNA2	2347.0
TERF2IP	2334.0
RAD1	2227.0
LIG1	2069.0
H2BC10	2021.0
MAD2L2	2006.0
RPA1	1885.0
SPIDR	1857.0
XRCC1	1781.0
RFC2	1760.0
GTF2H3	1736.0
TFPT	1719.0
ATRIP	1661.0
MNAT1	1602.0
ELL	1591.0
RIF1	1587.0
TOPBP1	1558.0
ACTB	1540.0
ALKBH5	1515.0
POLR2A	1481.0
RMI2	1319.0
RCHY1	1233.0
RUVBL1	1222.0
UBE2L6	1124.0
NBN	1064.0
FEN1	994.0
TERF1	989.0
POLE	963.0
KDM4A	920.0
POLI	832.0
RFC3	822.0
EP300	777.0
NHEJ1	769.0
CCNA1	745.0
INO80	736.0
H4C11	725.0
H4C5	654.0
FTO	652.0
EYA4	533.0
H2BC12	519.0
PAXIP1	479.0
REV3L	456.0
POLR2E	455.0
EME2	440.0
COPS7B	436.0
POLR2H	334.0
XAB2	332.0
SEM1	329.0
H4C4	162.0
UBE2B	105.0
MRE11	94.0
RAD23A	71.0
RAD51B	-34.0
ERCC4	-190.0
BRCA1	-237.0
UBC	-323.0
XRCC4	-355.0
GTF2H4	-482.0
ADPRS	-535.0
USP43	-543.0
POLR2F	-559.0
RNF4	-646.0
TOP3A	-739.0
FAAP100	-761.0
RFC1	-815.0
PARP1	-847.0
ALKBH2	-884.0
FAN1	-954.0
HUS1	-1084.0
PPP4C	-1140.0
MDC1	-1241.0
COPS3	-1252.0
GEN1	-1273.0
FANCC	-1290.0
RTEL1	-1361.0
ERCC2	-1393.0
POLM	-1508.0
ERCC6	-1544.0
ACTL6A	-1547.0
TINF2	-1596.0
ERCC3	-1766.0
USP1	-1859.0
BRIP1	-1946.0
POLH	-1949.0
INO80E	-1984.0
POLR2D	-2050.0
FANCA	-2165.0
ACTR8	-2201.0
RNF168	-2213.0
POLN	-2267.0
TDP1	-2362.0
TRIM25	-2471.0
BAP1	-2477.0
PPIE	-2503.0
EYA2	-2584.0
SUMO3	-2666.0
MGMT	-2681.0
MLH1	-2991.0
SUMO1	-3031.0
PRPF19	-3075.0
RAD18	-3084.0
GPS1	-3122.0
PMS2	-3201.0
NSD2	-3278.0
RAD9A	-3359.0
POLR2L	-3453.0
NFRKB	-3591.0
MSH3	-3682.0
GTF2H1	-3725.0
FANCL	-3763.0
H4C6	-3817.0
UBE2T	-3864.0
PRKDC	-3998.0
NEIL2	-4145.0
XRCC5	-4164.0
CCNA2	-4363.0
INO80D	-4392.0
EYA1	-4407.0
FAAP20	-4597.0
KDM4B	-4643.0
H3-4	-4773.0
PPP4R2	-4794.0
H2BC26	-4831.0
UBE2V2	-4928.0
REV1	-4967.0
RAD50	-5022.0
TERF2	-5078.0
SMUG1	-5111.0
FANCI	-5307.0
HERC2	-5391.0
H2AC18	-5415.5
H2AC19	-5415.5
CLSPN	-5454.0
XRCC3	-5618.0
UVSSA	-5750.0
ALKBH3	-5805.0
CHEK2	-5952.0
H4C13	-6090.0
FANCG	-6110.0
ASCC2	-6220.0
POLL	-6247.0
RPS27A	-6484.0
RBX1	-6897.0
POLD3	-7106.0
H2BC14	-7223.0
HMGN1	-7501.0
AQR	-7537.0
PPP5C	-7539.0
USP45	-7549.0
H2BC13	-7559.0
UBE2I	-7598.0
LIG4	-7738.0
MUTYH	-7910.0
H2AC14	-7938.0
PARG	-7979.0
H4C9	-8005.0
TIPIN	-8153.0
RAD51C	-9702.0
POLR2J	-10431.0

---

REACTOME_ASSEMBLY_OF_THE_ORC_COMPLEX_AT_THE_ORIGIN_OF_REPLICATION

REACTOME_ASSEMBLY_OF_THE_ORC_COMPLEX_AT_THE_ORIGIN_OF_REPLICATION

	1091
set	REACTOME_ASSEMBLY_OF_THE_ORC_COMPLEX_AT_THE_ORIGIN_OF_REPLICATION
setSize	62
pANOVA	1.04e-06
s.dist	0.359
p.adjustANOVA	7.13e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H3-3A	10816.0
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
H3C12	9726.0
H2BC21	9693.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
H2AZ1	9026.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H3-3A	10816.0
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
H3C12	9726.0
H2BC21	9693.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
H2AZ1	9026.0
H2AC20	9019.0
ORC2	8430.0
KPNB1	8399.0
ORC6	8363.0
KPNA6	8129.0
H3C4	7677.0
H2BC11	7363.0
H2BC5	7354.0
ORC1	6899.0
H2BC3	6877.0
H4C1	6505.0
H4C2	5849.0
H2AJ	5832.0
H2AX	5821.0
H4C12	5591.0
H4C8	5375.0
ORC5	4541.0
ORC4	4334.0
H3C6	4303.0
H2AZ2	4022.0
H2BC1	2654.0
H3C10	2553.0
H2BC10	2021.0
H3C1	733.0
H4C11	725.0
H4C5	654.0
H2BC12	519.0
H3C11	416.0
H4C4	162.0
H3C8	-350.0
ORC3	-828.0
H4C6	-3817.0
KPNA1	-4128.0
H3C3	-4506.0
H2BC26	-4831.0
H2AC18	-5415.5
H2AC19	-5415.5
H4C13	-6090.0
H2BC14	-7223.0
H2BC13	-7559.0
H2AC14	-7938.0
H4C9	-8005.0

---

REACTOME_DNA_REPLICATION_PRE_INITIATION

REACTOME_DNA_REPLICATION_PRE_INITIATION

	1101
set	REACTOME_DNA_REPLICATION_PRE_INITIATION
setSize	150
pANOVA	1.48e-06
s.dist	0.228
p.adjustANOVA	9.71e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H3-3A	10816.0
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
POLE2	10284.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
PSMD13	10036.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
H3C12	9726.0
H2BC21	9693.0
ANAPC10	9626.0
H2BC8	9455.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H3-3A	10816.0
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
POLE2	10284.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
PSMD13	10036.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
H3C12	9726.0
H2BC21	9693.0
ANAPC10	9626.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
UBE2S	9214.0
H2AZ1	9026.0
H2AC20	9019.0
UBB	8935.0
POLE4	8745.0
PSMA6	8609.0
CDC23	8577.0
ORC2	8430.0
KPNB1	8399.0
ORC6	8363.0
POLE3	8257.0
PSMC6	8173.0
KPNA6	8129.0
CDC26	8079.0
RPA3	7810.0
PSME3	7776.0
RPA2	7679.0
H3C4	7677.0
UBE2E1	7409.0
H2BC11	7363.0
H2BC5	7354.0
ORC1	6899.0
H2BC3	6877.0
PSMB3	6752.0
PSMD12	6656.0
H4C1	6505.0
MCM2	6216.0
DBF4	6178.0
ANAPC7	6124.0
PSMB7	6049.0
H4C2	5849.0
H2AJ	5832.0
H2AX	5821.0
ANAPC2	5784.0
H4C12	5591.0
ANAPC11	5571.0
PSMC1	5452.0
FZR1	5395.0
H4C8	5375.0
PSMD8	5087.0
ANAPC16	4927.0
PSMB10	4635.0
ORC5	4541.0
PSMD3	4433.0
CDC27	4430.0
UBE2C	4394.0
ORC4	4334.0
H3C6	4303.0
PSMA3	4156.0
H2AZ2	4022.0
PSMC2	3840.0
CDC45	3327.0
PSMC5	3099.0
CDT1	2997.0
CDK2	2988.0
UBA52	2963.0
PSMB1	2960.0
ANAPC4	2830.0
H2BC1	2654.0
PSMB2	2596.0
H3C10	2553.0
PSMA1	2497.0
PSMB5	2455.0
PSMD2	2443.0
PSMA7	2417.0
PSMB4	2281.0
PSMD4	2042.0
H2BC10	2021.0
RPA1	1885.0
PSME1	1571.0
PSME2	1245.0
PSMA2	1218.0
PSMB6	1163.0
POLE	963.0
H3C1	733.0
H4C11	725.0
H4C5	654.0
UBE2D1	557.0
CDC16	525.0
H2BC12	519.0
H3C11	416.0
SEM1	329.0
H4C4	162.0
POLA2	56.0
MCM6	47.0
PSMB8	-53.0
CDC6	-211.0
UBC	-323.0
H3C8	-350.0
PSMD5	-411.0
PSMA5	-534.0
ANAPC1	-538.0
PSMB9	-734.0
PSMD11	-805.0
ORC3	-828.0
MCM3	-889.0
MCM4	-1286.0
GMNN	-1366.0
PSMD7	-1937.0
PSMD9	-2906.0
PRIM2	-2930.0
MCM8	-2989.0
MCM5	-3052.0
ANAPC5	-3528.0
ANAPC15	-3556.0
H4C6	-3817.0
KPNA1	-4128.0
PSMC3	-4492.0
H3C3	-4506.0
MCM7	-4735.0
H2BC26	-4831.0
PSMD14	-5297.0
H2AC18	-5415.5
H2AC19	-5415.5
PSMD1	-5508.0
PSMD6	-5633.0
CDC7	-5634.0
PSMF1	-5638.0
H4C13	-6090.0
RPS27A	-6484.0
PSMC4	-6643.0
MCM10	-7100.0
H2BC14	-7223.0
PSMA4	-7243.0
H2BC13	-7559.0
PRIM1	-7751.0
H2AC14	-7938.0
H4C9	-8005.0

---

REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION

REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION

	1636
set	REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION
setSize	361
pANOVA	1.57e-06
s.dist	0.147
p.adjustANOVA	9.91e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
S100A9	11238
ZNRF1	11133
UBA7	11003
UFL1	10964
CD14	10922
RNF144B	10691
KLHL21	10674
ELOC	10605
UBE2O	10500
SIAH1	10498
HERC6	10428
HLA-B	10426
ELOB	10398
FBXW9	10332
RNF114	10213
MYLIP	10179
FBXO2	10103
PSMD13	10036
RNF7	10011
CTSL	10003

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
S100A9	11238.0
ZNRF1	11133.0
UBA7	11003.0
UFL1	10964.0
CD14	10922.0
RNF144B	10691.0
KLHL21	10674.0
ELOC	10605.0
UBE2O	10500.0
SIAH1	10498.0
HERC6	10428.0
HLA-B	10426.0
ELOB	10398.0
FBXW9	10332.0
RNF114	10213.0
MYLIP	10179.0
FBXO2	10103.0
PSMD13	10036.0
RNF7	10011.0
CTSL	10003.0
BECN1	9905.0
FBXO44	9891.0
MEX3C	9858.0
UBE2R2	9758.0
FBXO4	9716.0
LY96	9708.0
ANAPC10	9626.0
FBXO17	9542.0
SOCS3	9415.0
FBXO27	9308.0
B2M	9299.0
UBE2S	9214.0
FBXO41	9192.0
FBXL14	9191.0
CALR	9075.0
UBB	8935.0
MYD88	8923.0
HSPA5	8652.0
PSMA6	8609.0
LRR1	8583.0
CDC23	8577.0
HLA-E	8552.0
UBE2J1	8379.0
HLA-F	8377.0
CTSV	8307.0
TLR2	8292.0
FBXO6	8278.0
TLR6	8256.0
SOCS1	8254.0
RNF41	8200.0
RNF126	8195.0
PSMC6	8173.0
DTX3L	8157.0
RNF123	8106.0
CDC26	8079.0
UBE2N	8070.0
UBE2F	8046.0
FBXL15	8030.0
FBXO40	7828.0
SIAH2	7792.0
PSME3	7776.0
RBBP6	7765.0
UBE2G1	7751.0
FBXW2	7734.0
HERC1	7563.0
NCF2	7558.0
FBXL16	7516.0
UBE2E1	7409.0
RNF34	7366.0
S100A8	7358.0
KCTD7	7350.0
FBXO7	7315.0
TRIM37	7245.0
UBA5	7184.0
LRRC41	7036.0
SAR1B	6986.0
FBXL8	6943.0
RBCK1	6933.0
SNAP23	6848.0
PSMB3	6752.0
PSMD12	6656.0
SEC61B	6637.0
CANX	6634.0
FBXW4	6509.0
FBXL18	6456.0
TRIM32	6445.0
HLA-A	6401.0
FBXL3	6332.0
SEC23A	6281.0
ANAPC7	6124.0
ASB17	6101.0
PSMB7	6049.0
SEC24A	6013.0
UBE2Q2	5999.0
TRIM69	5979.0
UBR2	5942.0
S100A1	5936.0
KBTBD8	5876.0
CCNF	5786.0
ANAPC2	5784.0
NEDD4	5782.0
UBE2G2	5744.0
TRIM36	5742.0
SEC31A	5730.0
LNPEP	5689.0
UBA6	5671.0
AREL1	5656.0
RNF111	5654.0
ANAPC11	5571.0
PSMC1	5452.0
MGRN1	5427.0
FZR1	5395.0
RNF6	5374.0
GLMN	5365.0
KLHL3	5335.0
BLMH	5319.0
HLA-G	5246.0
ANAPC13	5208.0
SEC24B	5187.0
CUL3	5141.0
CUL2	5114.0
UBA3	5109.0
FBXO30	5088.0
PSMD8	5087.0
SEC61G	4933.0
KLHL42	4929.0
TRIP12	4859.5
UBE2D4	4768.0
UBE3A	4758.0
FBXO32	4726.0
FBXO22	4685.0
FGB	4682.0
ASB8	4662.0
HMGB1	4642.0
PSMB10	4635.0
GAN	4615.0
BTRC	4547.0
UBE2D2	4497.0
PSMD3	4433.0
CDC27	4430.0
UBE2C	4394.0
UBOX5	4350.0
UBE2V1	4269.0
TRIM63	4241.0
UBE2D3	4215.0
PSMA3	4156.0
CUL1	4104.0
TRIM4	4018.0
ASB6	3951.0
PSMC2	3840.0
TRIM9	3833.0
UBE2H	3736.0
RNF14	3666.0
ERAP1	3655.0
FBXL19	3346.0
TIRAP	3308.0
FBXW11	3290.0
KEAP1	3287.0
ZNRF2	3279.0
SMURF1	3156.0
PSMC5	3099.0
STX4	3018.0
FBXL5	2993.0
UBA52	2963.0
DZIP3	2962.0
PSMB1	2960.0
LONRF1	2916.0
FBXL4	2915.0
FBXO15	2898.0
LTN1	2853.0
UBE2W	2838.0
ANAPC4	2830.0
MIB2	2800.0
SKP2	2789.0
UBR4	2712.0
ASB3	2693.0
ASB14	2653.0
UBE2K	2605.0
PSMB2	2596.0
PSMA1	2497.0
PSMB5	2455.0
PSMD2	2443.0
PSMA7	2417.0
TPP2	2320.0
PSMB4	2281.0
HERC5	2263.0
KBTBD6	2248.0
KLHL5	2243.0
TRIM39	2218.0
CYBA	2203.0
ASB13	2183.0
UBE3C	2166.0
SEC22B	2144.0
FBXL22	2070.0
PSMD4	2042.0
VAMP3	2037.0
SPSB2	2004.0
UNKL	1971.0
PIK3R4	1925.0
SMURF2	1884.0
ARIH2	1876.0
SPSB1	1741.0
WWP1	1718.0
PSME1	1571.0
SKP1	1543.0
ITGAV	1426.0
UBE2M	1374.0
HECTD3	1324.0
TRAF7	1253.0
PSME2	1245.0
RCHY1	1233.0
PSMA2	1218.0
TRIM71	1207.0
PSMB6	1163.0
UBE2L6	1124.0
TLR1	1019.0
FBXW5	1016.0
LNX1	891.0
UBE3D	872.0
FBXO10	622.0
CBLB	592.0
PDIA3	575.0
DET1	562.0
UBE2D1	557.0
CDC16	525.0
ZBTB16	437.0
NPEPPS	413.0
SEC24D	369.0
MKRN1	368.0
SEM1	329.0
KLHL22	140.0
UBE2B	105.0
FBXL12	68.0
KLHL25	-49.0
PSMB8	-53.0
STUB1	-163.0
UBAC1	-195.0
KLHL2	-247.0
UBE4A	-305.0
UBC	-323.0
VHL	-326.0
SEC61A1	-335.0
RNF25	-368.0
PSMD5	-411.0
TRIM11	-454.0
CUL7	-486.0
HECTD1	-524.0
FBXO9	-529.0
PSMA5	-534.0
ANAPC1	-538.0
TRIM41	-546.0
CUL5	-608.0
UBE2E2	-637.0
RNF4	-646.0
SEC24C	-674.0
PSMB9	-734.0
HERC4	-769.0
PSME4	-771.0
PSMD11	-805.0
ATG7	-959.0
HECTD2	-1035.0
NCF4	-1049.0
ATG14	-1169.0
UBE2E3	-1308.0
UBE2U	-1382.0
TAPBP	-1446.0
TAP2	-1499.0
KLHL11	-1521.0
UBE3B	-1562.0
HERC3	-1611.0
BTBD1	-1667.0
RNF19A	-1672.0
VAMP8	-1697.0
ASB16	-1846.0
PSMD7	-1937.0
FBXW8	-2052.0
FBXW7	-2124.0
KLHL9	-2151.0
RNF130	-2175.0
FBXO11	-2211.0
UBR1	-2219.0
KCTD6	-2265.0
FBXL13	-2328.0
TAP1	-2361.0
TLR4	-2385.0
PRKN	-2446.0
HLA-C	-2543.0
MRC2	-2735.0
HACE1	-2836.0
PSMD9	-2906.0
IKBKB	-2956.0
LRSAM1	-3017.0
ITCH	-3047.0
FBXO31	-3115.0
CDC20	-3146.0
UBE2Q1	-3197.0
PIK3C3	-3214.0
FBXW12	-3218.0
RNF19B	-3466.0
ANAPC5	-3528.0
ERAP2	-3529.0
ASB1	-3654.0
UBE2L3	-3724.0
DCAF1	-3787.0
FBXL7	-3947.0
TRAIP	-4038.0
FBXL20	-4043.0
SH3RF1	-4197.0
HECW2	-4294.0
PSMC3	-4492.0
FBXO21	-4616.0
ASB7	-4692.0
PJA2	-4701.0
RNF220	-4804.0
UBE2V2	-4928.0
LMO7	-4958.0
UBE2Z	-5148.0
KLHL20	-5233.0
RNF182	-5239.0
PSMD14	-5297.0
CHUK	-5332.0
HERC2	-5391.0
PSMD1	-5508.0
RNF138	-5583.0
PSMD6	-5633.0
PSMF1	-5638.0
KBTBD7	-5701.0
RNF115	-5814.0
RNF217	-6005.0
ASB2	-6127.0
UBE2J2	-6144.0
THOP1	-6239.0
NEDD4L	-6474.0
RPS27A	-6484.0
PSMA8	-6587.0
ASB15	-6611.0
PSMC4	-6643.0
ASB18	-6738.0
SEC13	-6814.0
RBX1	-6897.0
RNF213	-7077.0
ITGB5	-7109.0
PSMA4	-7243.0
ASB4	-7276.0
SPSB4	-7316.0
ASB5	-7467.0
WSB1	-7487.0
CTSS	-7691.0
KLHL41	-7761.0
CDC34	-8133.0
SEC61A2	-8415.0
TRIM50	-8426.0
ASB10	-8729.0
FBXW10	-9010.0
CD36	-9061.0
FGA	-9164.0
BTBD6	-9173.0
TRIM21	-9335.0
PSMB11	-9711.0
FGG	-9928.0
CD207	-10363.0

---

REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS

REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS

	901
set	REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS
setSize	113
pANOVA	1.97e-06
s.dist	0.259
p.adjustANOVA	0.00012

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H3-3A	10816.0
HOXA1	10789.0
H2AC4	10558.0
H2BC17	10497.0
RARG	10410.0
H4C16	10315.0
H2BC15	10314.0
HOXB2	10263.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
HOXB4	9846.0
HOXA2	9751.0
H3C12	9726.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H3-3A	10816.0
HOXA1	10789.0
H2AC4	10558.0
H2BC17	10497.0
RARG	10410.0
H4C16	10315.0
H2BC15	10314.0
HOXB2	10263.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
HOXB4	9846.0
HOXA2	9751.0
H3C12	9726.0
H2BC21	9693.0
RARA	9534.0
HOXB3	9516.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
POLR2C	9358.0
HOXC4	9155.0
H2AZ1	9026.0
H2AC20	9019.0
RBBP5	8902.0
JUN	8891.0
HOXD3	8815.0
PAX6	8564.0
POLR2G	8490.0
HOXD1	8136.0
CNOT6	7759.0
H3C4	7677.0
H2BC11	7363.0
H2BC5	7354.0
RXRA	7109.0
H2BC3	6877.0
H4C1	6505.0
AJUBA	6380.0
RBBP4	6026.0
ZNF335	5908.0
HOXA4	5888.0
POLR2I	5881.0
H4C2	5849.0
H2AJ	5832.0
H2AX	5821.0
H4C12	5591.0
PKNOX1	5572.0
HOXD4	5508.0
H4C8	5375.0
EGR2	4620.0
YY1	4593.0
H3C6	4303.0
H2AZ2	4022.0
POLR2K	3416.0
CNOT9	3310.0
POLR2B	2795.0
H2BC1	2654.0
CREBBP	2578.0
H3C10	2553.0
MEIS1	2503.0
H2BC10	2021.0
CTCF	1635.0
POLR2A	1481.0
EP300	777.0
H3C1	733.0
H4C11	725.0
H4C5	654.0
H2BC12	519.0
PAXIP1	479.0
POLR2E	455.0
H3C11	416.0
POLR2H	334.0
EZH2	243.0
PAGR1	166.0
H4C4	162.0
H3C8	-350.0
POLR2F	-559.0
EED	-1311.0
HDAC3	-1583.0
PCGF2	-1658.0
KMT2C	-1702.0
POLR2D	-2050.0
ASH2L	-2432.0
MAFB	-2621.0
POLR2L	-3453.0
HOXA3	-3531.0
NCOA6	-3801.0
H4C6	-3817.0
NCOR1	-3868.0
WDR5	-3915.0
PIAS2	-4146.0
PBX1	-4429.0
H3C3	-4506.0
H2BC26	-4831.0
SUZ12	-4896.0
NCOA3	-4993.0
KMT2D	-5043.0
RARB	-5295.0
H2AC18	-5415.5
H2AC19	-5415.5
H4C13	-6090.0
H2BC14	-7223.0
H2BC13	-7559.0
H2AC14	-7938.0
H4C9	-8005.0
HOXB1	-8470.0
POLR2J	-10431.0

---

REACTOME_DNA_REPLICATION

REACTOME_DNA_REPLICATION

	1113
set	REACTOME_DNA_REPLICATION
setSize	178
pANOVA	2.4e-06
s.dist	0.205
p.adjustANOVA	0.00014

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H3-3A	10816.0
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
POLE2	10284.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
PSMD13	10036.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
H3C12	9726.0
H2BC21	9693.0
ANAPC10	9626.0
H2BC8	9455.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H3-3A	10816.0
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
POLE2	10284.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
PSMD13	10036.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
H3C12	9726.0
H2BC21	9693.0
ANAPC10	9626.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
UBE2S	9214.0
H2AZ1	9026.0
H2AC20	9019.0
UBB	8935.0
POLE4	8745.0
PSMA6	8609.0
CDC23	8577.0
PCNA	8551.0
GINS1	8549.0
ORC2	8430.0
KPNB1	8399.0
ORC6	8363.0
POLE3	8257.0
PSMC6	8173.0
KPNA6	8129.0
CDC26	8079.0
GINS4	8021.0
POLD4	7923.0
RPA3	7810.0
PSME3	7776.0
RPA2	7679.0
H3C4	7677.0
UBE2E1	7409.0
H2BC11	7363.0
H2BC5	7354.0
RFC4	7122.0
POLD1	7018.0
ORC1	6899.0
H2BC3	6877.0
PSMB3	6752.0
GINS2	6674.0
PSMD12	6656.0
H4C1	6505.0
MCM2	6216.0
POLD2	6199.0
DBF4	6178.0
ANAPC7	6124.0
PSMB7	6049.0
H4C2	5849.0
H2AJ	5832.0
H2AX	5821.0
ANAPC2	5784.0
RFC5	5739.0
H4C12	5591.0
ANAPC11	5571.0
PSMC1	5452.0
FZR1	5395.0
H4C8	5375.0
PSMD8	5087.0
ANAPC16	4927.0
PSMB10	4635.0
ORC5	4541.0
PSMD3	4433.0
CDC27	4430.0
UBE2C	4394.0
ORC4	4334.0
H3C6	4303.0
PSMA3	4156.0
CUL1	4104.0
H2AZ2	4022.0
PSMC2	3840.0
CDC45	3327.0
PSMC5	3099.0
CDT1	2997.0
CDK2	2988.0
UBA52	2963.0
PSMB1	2960.0
ANAPC4	2830.0
DNA2	2805.0
SKP2	2789.0
H2BC1	2654.0
PSMB2	2596.0
H3C10	2553.0
PSMA1	2497.0
PSMB5	2455.0
PSMD2	2443.0
PSMA7	2417.0
PSMB4	2281.0
LIG1	2069.0
PSMD4	2042.0
H2BC10	2021.0
GINS3	1900.0
RPA1	1885.0
RFC2	1760.0
PSME1	1571.0
SKP1	1543.0
PSME2	1245.0
PSMA2	1218.0
PSMB6	1163.0
FEN1	994.0
POLE	963.0
RFC3	822.0
CCNA1	745.0
H3C1	733.0
H4C11	725.0
H4C5	654.0
UBE2D1	557.0
CDC16	525.0
H2BC12	519.0
H3C11	416.0
SEM1	329.0
H4C4	162.0
POLA2	56.0
MCM6	47.0
PSMB8	-53.0
CDC6	-211.0
UBC	-323.0
H3C8	-350.0
PSMD5	-411.0
PSMA5	-534.0
ANAPC1	-538.0
PSMB9	-734.0
PSME4	-771.0
PSMD11	-805.0
RFC1	-815.0
ORC3	-828.0
MCM3	-889.0
MCM4	-1286.0
GMNN	-1366.0
PSMD7	-1937.0
CCNE2	-2648.0
PSMD9	-2906.0
PRIM2	-2930.0
MCM8	-2989.0
MCM5	-3052.0
ANAPC5	-3528.0
ANAPC15	-3556.0
H4C6	-3817.0
KPNA1	-4128.0
CCNA2	-4363.0
PSMC3	-4492.0
H3C3	-4506.0
MCM7	-4735.0
H2BC26	-4831.0
PSMD14	-5297.0
H2AC18	-5415.5
H2AC19	-5415.5
PSMD1	-5508.0
PSMD6	-5633.0
CDC7	-5634.0
PSMF1	-5638.0
H4C13	-6090.0
RPS27A	-6484.0
PSMA8	-6587.0
PSMC4	-6643.0
RBX1	-6897.0
MCM10	-7100.0
POLD3	-7106.0
H2BC14	-7223.0
PSMA4	-7243.0
H2BC13	-7559.0
PRIM1	-7751.0
CCNE1	-7855.0
H2AC14	-7938.0
H4C9	-8005.0
PSMB11	-9711.0

---

REACTOME_ECM_PROTEOGLYCANS

REACTOME_ECM_PROTEOGLYCANS

	537
set	REACTOME_ECM_PROTEOGLYCANS
setSize	73
pANOVA	2.48e-06
s.dist	-0.319
p.adjustANOVA	0.00014

Top enriched genes

Top 20 genes

GeneID	Gene Rank
DSPP	-9671
ITGB6	-8907
TNR	-8491
ASPN	-8444
COL5A1	-8421
COL6A6	-8274
COL5A2	-8166
AGRN	-8013
TGFB3	-7924
COL6A2	-7817
DMP1	-7719
COL4A4	-7607
IBSP	-7466
COL6A5	-7445
LUM	-7421
LAMA1	-7232
ITGB5	-7109
HSPG2	-6970
TNC	-6945
HAPLN1	-6919

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
DSPP	-9671
ITGB6	-8907
TNR	-8491
ASPN	-8444
COL5A1	-8421
COL6A6	-8274
COL5A2	-8166
AGRN	-8013
TGFB3	-7924
COL6A2	-7817
DMP1	-7719
COL4A4	-7607
IBSP	-7466
COL6A5	-7445
LUM	-7421
LAMA1	-7232
ITGB5	-7109
HSPG2	-6970
TNC	-6945
HAPLN1	-6919
COL4A2	-6813
MUSK	-6640
TNN	-6478
FN1	-6453
ITGA2B	-6213
ITGA7	-6168
LAMC1	-6158
DCN	-6098
MATN4	-6045
LAMB1	-5957
NCAM1	-5882
COL3A1	-5646
ITGB3	-4961
LAMA2	-4505
PTPRS	-4437
LAMB2	-4434
ITGAX	-4397
TNXB	-4310
LAMA5	-4204
MATN1	-4143
COL5A3	-4044
COL4A1	-3939
ITGA9	-3772
COL6A1	-3677
COL6A3	-3117
ITGA8	-2756
ACAN	-2046
COL4A3	-1751
COL1A2	-1423
TGFB1	-1410
LAMA4	-1149
LAMA3	-375
ITGB1	-205
DAG1	-41
VCAN	275
COL1A1	412
ITGA2	548
FMOD	1008
COL9A1	1187
ITGAV	1426
SERPINE1	3685
COL2A1	3703
COL9A2	3989
SPARC	4037
APP	4531
TGFB2	4960
LRP4	5025
MATN3	5285
VTN	6308
NCAN	6883
COL9A3	7370
COMP	7954
BCAN	8702

---

REACTOME_HDACS_DEACETYLATE_HISTONES

REACTOME_HDACS_DEACETYLATE_HISTONES

	548
set	REACTOME_HDACS_DEACETYLATE_HISTONES
setSize	85
pANOVA	4.36e-06
s.dist	0.288
p.adjustANOVA	0.000238

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC21	10743.0
H2AC4	10558.0
H2BC17	10497.0
H2AC15	10342.0
H4C16	10315.0
H2BC15	10314.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC16	9919.0
H2AC8	9917.0
H3C12	9726.0
H2BC21	9693.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC21	10743.0
H2AC4	10558.0
H2BC17	10497.0
H2AC15	10342.0
H4C16	10315.0
H2BC15	10314.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC16	9919.0
H2AC8	9917.0
H3C12	9726.0
H2BC21	9693.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
H2AC20	9019.0
REST	8553.0
SAP30L	8446.0
H2AC11	8376.0
H2AC12	8285.0
H2AC17	8217.0
H3C4	7677.0
GATAD2B	7509.0
CHD3	7459.0
H2BC11	7363.0
H2BC5	7354.0
H2BC3	6877.0
BRMS1	6820.0
H4C1	6505.0
RBBP4	6026.0
H4C2	5849.0
HDAC2	5842.0
GATAD2A	5679.0
ARID4A	5619.0
H4C12	5591.0
H4C8	5375.0
SUDS3	4594.0
H3C6	4303.0
GPS2	4260.0
MTA3	4233.0
HMG20B	3384.0
ARID4B	3360.0
NCOR2	3299.0
HDAC1	3086.0
MTA2	3044.0
HDAC10	2816.0
H2BC1	2654.0
H3C10	2553.0
H2BC10	2021.0
TBL1XR1	1940.0
SAP30	1886.0
CHD4	1146.0
H3C1	733.0
H4C11	725.0
H4C5	654.0
H2BC12	519.0
H3C11	416.0
H4C4	162.0
RCOR1	102.0
H3C8	-350.0
PHF21A	-1187.0
SAP18	-1189.0
HDAC3	-1583.0
H2AC1	-1730.0
KDM1A	-1770.0
H2AC13	-2215.0
H4C6	-3817.0
NCOR1	-3868.0
MBD3	-4382.0
H3C3	-4506.0
H2BC26	-4831.0
H2AC25	-5226.0
H2AC18	-5415.5
H2AC19	-5415.5
H4C13	-6090.0
MTA1	-6195.0
H2BC14	-7223.0
H2BC13	-7559.0
H2AC14	-7938.0
H4C9	-8005.0

---

REACTOME_DRUG_ADME

REACTOME_DRUG_ADME

	1593
set	REACTOME_DRUG_ADME
setSize	103
pANOVA	4.77e-06
s.dist	-0.261
p.adjustANOVA	0.000252

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GSTA1	-10436
CYP2C8	-10061
SLC22A7	-9953
UGT2B7	-9449
AKR1C1	-9344
ACSM4	-9189
GLYATL3	-9132
CES1	-8976
PCK1	-8954
ALB	-8941
SLC22A1	-8400
UGT2B11	-8383
SLC28A3	-8302
GLYATL1	-8251
SLC22A8	-8247
GLYATL2	-8185
GGT5	-8126
GLYAT	-8124
SLC22A2	-7925
UGT1A6	-7901

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GSTA1	-10436
CYP2C8	-10061
SLC22A7	-9953
UGT2B7	-9449
AKR1C1	-9344
ACSM4	-9189
GLYATL3	-9132
CES1	-8976
PCK1	-8954
ALB	-8941
SLC22A1	-8400
UGT2B11	-8383
SLC28A3	-8302
GLYATL1	-8251
SLC22A8	-8247
GLYATL2	-8185
GGT5	-8126
GLYAT	-8124
SLC22A2	-7925
UGT1A6	-7901
CYP2C9	-7715
SLCO1A2	-7546
UGT2A1	-7444
UGT2A3	-7334
SLCO2B1	-7252
GGT1	-7031
ABCC2	-6901
UGT1A7	-6843
CYP2E1	-6828
ADH1A	-6802
UGT1A9	-6775
SLC29A2	-6767
XDH	-6377
UGT2A2	-6376
UGT1A3	-6302
UGT1A4	-6279
UGT1A10	-6084
UGT1A5	-6057
GGT6	-5978
ACSM5	-5922
CYP3A4	-5840
UGT1A8	-5809
UGT1A1	-5771
HSD11B2	-5703
SLC28A2	-5662
GSTA2	-5047
SLCO1B3	-4866
PON1	-4679
SULT2A1	-4406
CES2	-4267
UGT2B17	-4254
BSG	-3999
TPMT	-3788
ABCB1	-3584
VAV2	-3550
SERPINA6	-3273
SULT1E1	-3268
NAT1	-2803
IMPDH2	-2751
SLC29A1	-2626
ABCC5	-2205
SLC22A3	-2076
HSD11B1	-1932
GUK1	-1760
ABCC4	-1323
GSTP1	-1213
UGT3A1	-1059
SLC29A3	-1012
ABCC3	-462
UGT2B4	-37
CYP2C19	15
ADAL	40
ACSM2B	208
GSTM1	365
ABCG2	946
ABCC1	1293
NT5C2	2091
BCHE	2586
ADA	2808
VAV3	2908
VAV1	2979
SULT1C4	3376
ACY1	3426
NME1	3623
UGT3A2	3832
GGT7	3881
SLCO1B1	4293
ADK	4695
NAT2	4953
GMPS	5280
NUDT15	7113
CYP2D6	7274
CNDP2	8042
IMPDH1	8149
SULT1A1	8282
NME2	8381
SLC16A1	8472
PNP	8683
ITPA	8732
RAC1	8876
UGT2B15	9203
PON3	10194
ACSM2A	11298

---

REACTOME_HOMOLOGY_DIRECTED_REPAIR

REACTOME_HOMOLOGY_DIRECTED_REPAIR

	1010
set	REACTOME_HOMOLOGY_DIRECTED_REPAIR
setSize	132
pANOVA	4.92e-06
s.dist	0.23
p.adjustANOVA	0.000252

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
POLE2	10284.0
H4C3	10086.0
H2BC4	9994.0
H2BC9	9978.5
H2BC6	9964.0
BABAM1	9748.0
TIMELESS	9697.0
H2BC21	9693.0
BRCA2	9605.0
SIRT6	9456.0
H2BC8	9455.0
H2BC7	9407.5
MUS81	9057.0
UBB	8935.0
RNF8	8912.0
SUMO2	8839.0
POLE4	8745.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
POLE2	10284.0
H4C3	10086.0
H2BC4	9994.0
H2BC9	9978.5
H2BC6	9964.0
BABAM1	9748.0
TIMELESS	9697.0
H2BC21	9693.0
BRCA2	9605.0
SIRT6	9456.0
H2BC8	9455.0
H2BC7	9407.5
MUS81	9057.0
UBB	8935.0
RNF8	8912.0
SUMO2	8839.0
POLE4	8745.0
LIG3	8613.0
PCNA	8551.0
ABRAXAS1	8286.0
BARD1	8265.0
POLE3	8257.0
EME1	8101.0
TP53BP1	8084.0
UBE2N	8070.0
RAD52	7991.0
POLD4	7923.0
RPA3	7810.0
RAD51AP1	7731.0
RPA2	7679.0
SLX4	7566.0
PALB2	7482.0
RAD9B	7481.0
H2BC11	7363.0
H2BC5	7354.0
RFC4	7122.0
POLD1	7018.0
WRN	6947.0
H2BC3	6877.0
POLK	6717.0
RBBP8	6518.0
H4C1	6505.0
EXO1	6320.0
POLD2	6199.0
RMI1	6032.0
BLM	5877.0
H4C2	5849.0
H2AX	5821.0
XRCC2	5800.0
KAT5	5792.0
PARP2	5768.0
RFC5	5739.0
POLQ	5714.0
H4C12	5591.0
PIAS4	5432.0
H4C8	5375.0
ATM	4998.0
RAD51D	4279.0
RHNO1	4015.0
RAD17	3742.0
ATR	3678.0
ERCC1	3506.0
UIMC1	3022.0
CDK2	2988.0
UBA52	2963.0
DNA2	2805.0
H2BC1	2654.0
ABL1	2597.0
CHEK1	2585.0
RAD51	2407.0
BABAM2	2351.0
RAD1	2227.0
H2BC10	2021.0
RPA1	1885.0
SPIDR	1857.0
XRCC1	1781.0
RFC2	1760.0
ATRIP	1661.0
TOPBP1	1558.0
RMI2	1319.0
NBN	1064.0
FEN1	994.0
POLE	963.0
RFC3	822.0
CCNA1	745.0
H4C11	725.0
H4C5	654.0
H2BC12	519.0
EME2	440.0
SEM1	329.0
H4C4	162.0
MRE11	94.0
RAD51B	-34.0
ERCC4	-190.0
BRCA1	-237.0
UBC	-323.0
RNF4	-646.0
TOP3A	-739.0
RFC1	-815.0
PARP1	-847.0
HUS1	-1084.0
PPP4C	-1140.0
MDC1	-1241.0
GEN1	-1273.0
RTEL1	-1361.0
BRIP1	-1946.0
POLH	-1949.0
RNF168	-2213.0
NSD2	-3278.0
RAD9A	-3359.0
H4C6	-3817.0
CCNA2	-4363.0
H3-4	-4773.0
PPP4R2	-4794.0
H2BC26	-4831.0
UBE2V2	-4928.0
RAD50	-5022.0
HERC2	-5391.0
CLSPN	-5454.0
XRCC3	-5618.0
H4C13	-6090.0
RPS27A	-6484.0
POLD3	-7106.0
H2BC14	-7223.0
H2BC13	-7559.0
UBE2I	-7598.0
H4C9	-8005.0
TIPIN	-8153.0
RAD51C	-9702.0

---

REACTOME_ERCC6_CSB_AND_EHMT2_G9A_POSITIVELY_REGULATE_RRNA_EXPRESSION

REACTOME_ERCC6_CSB_AND_EHMT2_G9A_POSITIVELY_REGULATE_RRNA_EXPRESSION

	738
set	REACTOME_ERCC6_CSB_AND_EHMT2_G9A_POSITIVELY_REGULATE_RRNA_EXPRESSION
setSize	68
pANOVA	5.88e-06
s.dist	0.318
p.adjustANOVA	0.000293

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H3-3A	10816.0
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
H3C12	9726.0
H2BC21	9693.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
H2AZ1	9026.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H3-3A	10816.0
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
H3C12	9726.0
H2BC21	9693.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
H2AZ1	9026.0
H2AC20	9019.0
H3C4	7677.0
GATAD2B	7509.0
CHD3	7459.0
H2BC11	7363.0
H2BC5	7354.0
H2BC3	6877.0
TTF1	6686.0
H4C1	6505.0
RBBP4	6026.0
H4C2	5849.0
HDAC2	5842.0
H2AJ	5832.0
H2AX	5821.0
GATAD2A	5679.0
H4C12	5591.0
CBX3	5436.0
H4C8	5375.0
H3C6	4303.0
MTA3	4233.0
H2AZ2	4022.0
HDAC1	3086.0
MTA2	3044.0
H2BC1	2654.0
H3C10	2553.0
H2BC10	2021.0
CHD4	1146.0
H3C1	733.0
H4C11	725.0
H4C5	654.0
H2BC12	519.0
H3C11	416.0
H4C4	162.0
H3C8	-350.0
ERCC6	-1544.0
H4C6	-3817.0
EHMT2	-3897.0
MBD3	-4382.0
H3C3	-4506.0
H2BC26	-4831.0
H2AC18	-5415.5
H2AC19	-5415.5
H4C13	-6090.0
MTA1	-6195.0
H2BC14	-7223.0
H2BC13	-7559.0
H2AC14	-7938.0
H4C9	-8005.0

---

REACTOME_POSITIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION

REACTOME_POSITIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION

	851
set	REACTOME_POSITIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION
setSize	98
pANOVA	6.62e-06
s.dist	0.263
p.adjustANOVA	0.000319

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H3-3A	10816.0
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
H3C12	9726.0
H2BC21	9693.0
H2BC8	9455.0
TAF1A	9448.0
H2AC7	9407.5
H2BC7	9407.5

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H3-3A	10816.0
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
H3C12	9726.0
H2BC21	9693.0
H2BC8	9455.0
TAF1A	9448.0
H2AC7	9407.5
H2BC7	9407.5
H2AZ1	9026.0
H2AC20	9019.0
POLR1D	8979.0
MYO1C	8817.0
H3C4	7677.0
POLR1H	7546.0
GATAD2B	7509.0
DDX21	7483.0
CHD3	7459.0
H2BC11	7363.0
H2BC5	7354.0
POLR1A	7174.0
H2BC3	6877.0
TTF1	6686.0
H4C1	6505.0
POLR1E	6272.0
RBBP4	6026.0
H4C2	5849.0
HDAC2	5842.0
H2AJ	5832.0
H2AX	5821.0
GATAD2A	5679.0
H4C12	5591.0
CBX3	5436.0
H4C8	5375.0
DEK	5370.0
BAZ1B	4400.0
H3C6	4303.0
MTA3	4233.0
GSK3B	4062.0
H2AZ2	4022.0
SMARCA5	3945.0
POLR2K	3416.0
HDAC1	3086.0
MTA2	3044.0
H2BC1	2654.0
H3C10	2553.0
POLR1F	2268.0
POLR1G	2079.0
H2BC10	2021.0
POLR1B	1577.0
ACTB	1540.0
CHD4	1146.0
TAF1B	887.0
KAT2B	811.0
EP300	777.0
H3C1	733.0
H4C11	725.0
H4C5	654.0
H2BC12	519.0
POLR2E	455.0
H3C11	416.0
POLR2H	334.0
H4C4	162.0
H3C8	-350.0
POLR2F	-559.0
SF3B1	-578.0
TBP	-1504.0
ERCC6	-1544.0
TAF1D	-2325.0
MYBBP1A	-2330.0
POLR2L	-3453.0
H4C6	-3817.0
EHMT2	-3897.0
MBD3	-4382.0
KAT2A	-4470.0
POLR1C	-4475.0
H3C3	-4506.0
H2BC26	-4831.0
H2AC18	-5415.5
H2AC19	-5415.5
H4C13	-6090.0
MTA1	-6195.0
H2BC14	-7223.0
TAF1C	-7464.0
H2BC13	-7559.0
H2AC14	-7938.0
H4C9	-8005.0

---

REACTOME_COLLAGEN_FORMATION

REACTOME_COLLAGEN_FORMATION

	117
set	REACTOME_COLLAGEN_FORMATION
setSize	88
pANOVA	7.19e-06
s.dist	-0.277
p.adjustANOVA	0.00033

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ADAMTS14	-9585
COL27A1	-9463
COL28A1	-9261
MMP7	-8911
COL5A1	-8421
COL13A1	-8413
P3H3	-8348
COL6A6	-8274
COL5A2	-8166
MMP20	-7932
MMP3	-7908
COL6A2	-7817
CTSS	-7691
COL7A1	-7631
COL4A4	-7607
LOXL2	-7577
COL11A2	-7540
COL6A5	-7445
COL17A1	-7374
ADAMTS2	-7308

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ADAMTS14	-9585
COL27A1	-9463
COL28A1	-9261
MMP7	-8911
COL5A1	-8421
COL13A1	-8413
P3H3	-8348
COL6A6	-8274
COL5A2	-8166
MMP20	-7932
MMP3	-7908
COL6A2	-7817
CTSS	-7691
COL7A1	-7631
COL4A4	-7607
LOXL2	-7577
COL11A2	-7540
COL6A5	-7445
COL17A1	-7374
ADAMTS2	-7308
P3H2	-7040
COL4A2	-6813
LOXL4	-6551
COL23A1	-6393
PLOD2	-5706
COL3A1	-5646
COL18A1	-5630
TLL2	-5477
COL20A1	-5164
DST	-4764
LAMC2	-4757
P4HA1	-4708
SERPINH1	-4545
PXDN	-4113
COL5A3	-4044
MMP13	-4021
ITGB4	-3971
COL4A1	-3939
COL6A1	-3677
PCOLCE2	-3620
COL22A1	-3566
COL16A1	-3559
BMP1	-3446
COL21A1	-3345
P4HA3	-3252
COL8A1	-3145
COL6A3	-3117
COL26A1	-3055
LAMB3	-2922
ADAMTS3	-2693
COL14A1	-2593
COL25A1	-2566
TLL1	-2535
MMP9	-2279
CD151	-2081
CTSB	-1891
COL4A3	-1751
COL12A1	-1678
COL1A2	-1423
PLOD3	-1319
COL10A1	-1268
COL15A1	-923
P4HA2	-906
P3H1	-392
LAMA3	-375
COLGALT2	-320
COL24A1	-7
LOXL3	307
COL1A1	412
COL19A1	1022
LOXL1	1091
COL9A1	1187
COL8A2	1342
COL11A1	1634
COLGALT1	3158
LOX	3501
COL2A1	3703
COL9A2	3989
PPIB	4706
PLEC	4735
PLOD1	5181
PCOLCE	5794
COL9A3	7370
CTSV	8307
CRTAP	8820
P4HB	9206
CTSL	10003
ITGA6	10516

---

REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION

REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION

	437
set	REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION
setSize	138
pANOVA	7.24e-06
s.dist	0.221
p.adjustANOVA	0.00033

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H3-3A	10816.0
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
H3C12	9726.0
H2BC21	9693.0
H2BC8	9455.0
TAF1A	9448.0
H2AC7	9407.5
H2BC7	9407.5

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H3-3A	10816.0
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
H3C12	9726.0
H2BC21	9693.0
H2BC8	9455.0
TAF1A	9448.0
H2AC7	9407.5
H2BC7	9407.5
H2AZ1	9026.0
H2AC20	9019.0
POLR1D	8979.0
MYO1C	8817.0
SAP30L	8446.0
CCNH	8147.0
MTF2	7930.0
H3C4	7677.0
POLR1H	7546.0
GATAD2B	7509.0
DDX21	7483.0
CHD3	7459.0
H2BC11	7363.0
H2BC5	7354.0
TET2	7249.0
POLR1A	7174.0
H2BC3	6877.0
CDK7	6742.0
TTF1	6686.0
TDG	6613.0
H4C1	6505.0
POLR1E	6272.0
RBBP4	6026.0
JARID2	5998.0
H4C2	5849.0
HDAC2	5842.0
H2AJ	5832.0
H2AX	5821.0
SAP130	5785.0
GATAD2A	5679.0
DNMT3A	5642.0
H4C12	5591.0
UHRF1	5470.0
CBX3	5436.0
H4C8	5375.0
DEK	5370.0
TET3	5112.0
GTF2H5	5045.0
SUDS3	4594.0
BAZ1B	4400.0
H3C6	4303.0
MTA3	4233.0
GSK3B	4062.0
H2AZ2	4022.0
SMARCA5	3945.0
PHF1	3923.0
POLR2K	3416.0
ARID4B	3360.0
HDAC1	3086.0
MTA2	3044.0
H2BC1	2654.0
H3C10	2553.0
SIN3A	2466.0
TET1	2452.0
POLR1F	2268.0
POLR1G	2079.0
H2BC10	2021.0
SAP30	1886.0
GTF2H3	1736.0
MNAT1	1602.0
POLR1B	1577.0
ACTB	1540.0
CHD4	1146.0
AEBP2	976.0
MBD2	904.0
TAF1B	887.0
DNMT1	817.0
KAT2B	811.0
EP300	777.0
H3C1	733.0
H4C11	725.0
H4C5	654.0
H2BC12	519.0
POLR2E	455.0
H3C11	416.0
RRP8	415.0
POLR2H	334.0
EZH2	243.0
H4C4	162.0
DNMT3L	133.0
BAZ2A	-40.0
H3C8	-350.0
PHF19	-475.0
GTF2H4	-482.0
POLR2F	-559.0
SF3B1	-578.0
SAP18	-1189.0
EED	-1311.0
ERCC2	-1393.0
TBP	-1504.0
ERCC6	-1544.0
ERCC3	-1766.0
DNMT3B	-2120.0
TAF1D	-2325.0
MYBBP1A	-2330.0
UBTF	-2331.0
POLR2L	-3453.0
GTF2H1	-3725.0
SAP30BP	-3755.0
H4C6	-3817.0
EHMT2	-3897.0
SIRT1	-4139.0
MBD3	-4382.0
KAT2A	-4470.0
POLR1C	-4475.0
H3C3	-4506.0
H2BC26	-4831.0
SUZ12	-4896.0
SIN3B	-5393.0
H2AC18	-5415.5
H2AC19	-5415.5
H4C13	-6090.0
MTA1	-6195.0
H2BC14	-7223.0
TAF1C	-7464.0
H2BC13	-7559.0
H2AC14	-7938.0
H4C9	-8005.0

---

REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1

REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1

	1272
set	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1
setSize	229
pANOVA	7.57e-06
s.dist	0.172
p.adjustANOVA	0.000336

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SOCS4	10822.0
H3-3A	10816.0
NFE2	10812.0
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
PF4	10175.0
H3-3B	10095.0
H4C3	10086.0
LMO2	10082.0
H2AC6	10052.0
H3C2	10037.0
PSMD13	10036.0
CTSL	10003.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SOCS4	10822.0
H3-3A	10816.0
NFE2	10812.0
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
PF4	10175.0
H3-3B	10095.0
H4C3	10086.0
LMO2	10082.0
H2AC6	10052.0
H3C2	10037.0
PSMD13	10036.0
CTSL	10003.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
CSNK2A1	9778.0
H3C12	9726.0
H2BC21	9693.0
H2BC8	9455.0
SOCS3	9415.0
H2AC7	9407.5
H2BC7	9407.5
NR4A3	9398.0
TNRC6B	9323.0
SMARCE1	9314.0
LDB1	9297.0
H2AZ1	9026.0
H2AC20	9019.0
SPI1	9010.0
UBB	8935.0
RBBP5	8902.0
ACTL6B	8734.0
PSMA6	8609.0
SMARCD3	8540.0
CTLA4	8505.0
CTSV	8307.0
RNF2	8302.0
PSMC6	8173.0
CCNH	8147.0
PCGF5	8078.0
IL2RA	7909.0
MIR27A	7889.0
PTPN11	7860.0
PSME3	7776.0
CLDN5	7701.0
H3C4	7677.0
MYB	7392.0
H2BC11	7363.0
H2BC5	7354.0
MOV10	7179.0
H2BC3	6877.0
ARID1A	6834.0
CBFB	6811.0
CBX4	6802.0
PSMB3	6752.0
CDK7	6742.0
PSMD12	6656.0
OCLN	6601.0
H4C1	6505.0
RYBP	6493.0
BMI1	6356.0
ELF1	6244.0
CSNK2B	6147.0
PSMB7	6049.0
ARID2	5986.0
GPAM	5938.0
ESR1	5862.0
CBX2	5858.0
H4C2	5849.0
H2AJ	5832.0
H2AX	5821.0
H4C12	5591.0
PSMC1	5452.0
H4C8	5375.0
PRKCB	5164.0
IL3	5133.0
KMT2E	5120.0
PSMD8	5087.0
CTSK	5006.0
CSNK2A2	4931.0
PSMB10	4635.0
RSPO3	4589.0
CCND3	4481.0
SMARCD1	4478.0
PSMD3	4433.0
H3C6	4303.0
AGO1	4301.0
PRMT1	4277.0
TNRC6A	4276.0
SMARCA2	4199.0
PSMA3	4156.0
TCF12	4030.0
H2AZ2	4022.0
RUNX2	4006.0
PSMC2	3840.0
SRC	3558.0
ZFPM1	3309.0
RUNX1	3122.0
PSMC5	3099.0
HDAC1	3086.0
TP73	2972.0
UBA52	2963.0
PSMB1	2960.0
ARID1B	2763.0
H2BC1	2654.0
PHC1	2610.0
ABL1	2597.0
PSMB2	2596.0
CREBBP	2578.0
H3C10	2553.0
SCMH1	2508.0
PSMA1	2497.0
SIN3A	2466.0
PSMB5	2455.0
PSMD2	2443.0
PSMA7	2417.0
NFATC2	2401.0
KMT2A	2369.0
CCND1	2318.0
PSMB4	2281.0
YAP1	2136.0
THBS1	2088.0
PSMD4	2042.0
H2BC10	2021.0
SETD1A	1753.0
GATA2	1695.0
MNAT1	1602.0
PSME1	1571.0
YAF2	1562.0
PSME2	1245.0
PSMA2	1218.0
PSMB6	1163.0
CBX8	1158.0
AXIN1	1098.0
KAT2B	811.0
EP300	777.0
H3C1	733.0
PML	732.0
H4C11	725.0
H4C5	654.0
H2BC12	519.0
H3C11	416.0
PRMT6	389.0
SEM1	329.0
BLK	314.0
H4C4	162.0
CCND2	11.0
PSMB8	-53.0
UBC	-323.0
H3C8	-350.0
LGALS3	-374.0
PSMD5	-411.0
DPY30	-441.0
CDK6	-504.0
PSMA5	-534.0
SETD1B	-663.0
RING1	-719.0
PSMB9	-734.0
PSME4	-771.0
PSMD11	-805.0
PHC3	-931.0
AGO4	-1047.0
TNRC6C	-1236.0
CSF2	-1429.0
ACTL6A	-1547.0
PRKCQ	-1576.0
TJP1	-1608.0
KMT2C	-1702.0
CR1	-1768.0
HIPK2	-1861.0
PSMD7	-1937.0
GATA3	-2179.0
KCTD6	-2265.0
TAL1	-2319.0
ASH2L	-2432.0
AGO3	-2452.0
PSMD9	-2906.0
ITCH	-3047.0
H4C6	-3817.0
WDR5	-3915.0
GP1BA	-3953.0
KMT2B	-3968.0
AUTS2	-3975.0
PBRM1	-4136.0
ELF2	-4260.0
PHC2	-4284.0
SMARCA4	-4396.0
PSMC3	-4492.0
H3C3	-4506.0
TCF3	-4646.0
SMARCC1	-4778.0
H2BC26	-4831.0
LIFR	-4997.0
KMT2D	-5043.0
CBX6	-5151.0
SMARCD2	-5201.0
LMO1	-5207.0
PAX5	-5231.0
PSMD14	-5297.0
SMARCB1	-5336.0
SIN3B	-5393.0
H2AC18	-5415.5
H2AC19	-5415.5
TNFRSF18	-5466.0
PSMD1	-5508.0
PSMD6	-5633.0
PSMF1	-5638.0
H4C13	-6090.0
SMARCC2	-6163.0
ITGA2B	-6213.0
IL2	-6245.0
RPS27A	-6484.0
PSMA8	-6587.0
PSMC4	-6643.0
AGO2	-7172.0
H2BC14	-7223.0
PSMA4	-7243.0
H2BC13	-7559.0
H2AC14	-7938.0
H4C9	-8005.0
MYL9	-8068.0
SERPINB13	-8397.0
IFNG	-8460.0
PSMB11	-9711.0

---

REACTOME_CONDENSATION_OF_PROPHASE_CHROMOSOMES

REACTOME_CONDENSATION_OF_PROPHASE_CHROMOSOMES

	480
set	REACTOME_CONDENSATION_OF_PROPHASE_CHROMOSOMES
setSize	66
pANOVA	7.95e-06
s.dist	0.318
p.adjustANOVA	0.000343

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H3-3A	10816.0
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
H3C12	9726.0
H2BC21	9693.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
CCNB1	9175.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H3-3A	10816.0
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
H3C12	9726.0
H2BC21	9693.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
CCNB1	9175.0
H2AZ1	9026.0
H2AC20	9019.0
KMT5A	8915.0
H3C4	7677.0
H2BC11	7363.0
H2BC5	7354.0
MCPH1	6889.0
H2BC3	6877.0
H4C1	6505.0
H4C2	5849.0
H2AJ	5832.0
H2AX	5821.0
H4C12	5591.0
CDK1	5463.0
H4C8	5375.0
SET	5356.0
H3C6	4303.0
H2AZ2	4022.0
H2BC1	2654.0
H3C10	2553.0
PLK1	2308.0
SMC4	2289.0
H2BC10	2021.0
NCAPD3	1434.0
RB1	1335.0
SMC2	1295.0
NCAPG2	1015.0
H3C1	733.0
H4C11	725.0
H4C5	654.0
H2BC12	519.0
H3C11	416.0
H4C4	162.0
H3C8	-350.0
H4C6	-3817.0
H3C3	-4506.0
H3-4	-4773.0
H2BC26	-4831.0
H2AC18	-5415.5
H2AC19	-5415.5
H4C13	-6090.0
H2BC14	-7223.0
H2BC13	-7559.0
H2AC14	-7938.0
H4C9	-8005.0
NCAPH2	-8346.0

---

REACTOME_BASE_EXCISION_REPAIR

REACTOME_BASE_EXCISION_REPAIR

	1164
set	REACTOME_BASE_EXCISION_REPAIR
setSize	87
pANOVA	1.12e-05
s.dist	0.272
p.adjustANOVA	0.000469

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
POLE2	10284.0
MPG	10193.0
H4C3	10086.0
H2AC6	10052.0
H2BC4	9994.0
H2BC9	9978.5
H2BC6	9964.0
H2AC8	9917.0
H2BC21	9693.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
H2AZ1	9026.0
H2AC20	9019.0
POLE4	8745.0
LIG3	8613.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
POLE2	10284.0
MPG	10193.0
H4C3	10086.0
H2AC6	10052.0
H2BC4	9994.0
H2BC9	9978.5
H2BC6	9964.0
H2AC8	9917.0
H2BC21	9693.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
H2AZ1	9026.0
H2AC20	9019.0
POLE4	8745.0
LIG3	8613.0
PCNA	8551.0
POLE3	8257.0
OGG1	7957.0
POLD4	7923.0
RPA3	7810.0
RPA2	7679.0
H2BC11	7363.0
H2BC5	7354.0
PNKP	7256.0
RFC4	7122.0
POLD1	7018.0
H2BC3	6877.0
TDG	6613.0
H4C1	6505.0
POLD2	6199.0
MBD4	5956.0
H4C2	5849.0
H2AJ	5832.0
H2AX	5821.0
PARP2	5768.0
RFC5	5739.0
H4C12	5591.0
H4C8	5375.0
POT1	5008.0
NEIL1	4801.0
H2AZ2	4022.0
ACD	3521.5
NEIL3	3423.0
POLB	3419.0
UNG	3329.0
H2BC1	2654.0
NTHL1	2530.0
APEX1	2373.0
TERF2IP	2334.0
LIG1	2069.0
H2BC10	2021.0
RPA1	1885.0
XRCC1	1781.0
RFC2	1760.0
FEN1	994.0
TERF1	989.0
POLE	963.0
RFC3	822.0
H4C11	725.0
H4C5	654.0
H2BC12	519.0
H4C4	162.0
ADPRS	-535.0
RFC1	-815.0
PARP1	-847.0
TINF2	-1596.0
H4C6	-3817.0
NEIL2	-4145.0
H3-4	-4773.0
H2BC26	-4831.0
TERF2	-5078.0
SMUG1	-5111.0
H2AC18	-5415.5
H2AC19	-5415.5
H4C13	-6090.0
POLD3	-7106.0
H2BC14	-7223.0
H2BC13	-7559.0
MUTYH	-7910.0
H2AC14	-7938.0
PARG	-7979.0
H4C9	-8005.0

---

REACTOME_DNA_METHYLATION

REACTOME_DNA_METHYLATION

	858
set	REACTOME_DNA_METHYLATION
setSize	58
pANOVA	1.18e-05
s.dist	0.333
p.adjustANOVA	0.000485

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H3-3A	10816.0
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
H3C12	9726.0
H2BC21	9693.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
H2AZ1	9026.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H3-3A	10816.0
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
H3C12	9726.0
H2BC21	9693.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
H2AZ1	9026.0
H2AC20	9019.0
H3C4	7677.0
H2BC11	7363.0
H2BC5	7354.0
H2BC3	6877.0
H4C1	6505.0
H4C2	5849.0
H2AJ	5832.0
H2AX	5821.0
DNMT3A	5642.0
H4C12	5591.0
UHRF1	5470.0
H4C8	5375.0
H3C6	4303.0
H2AZ2	4022.0
H2BC1	2654.0
H3C10	2553.0
H2BC10	2021.0
DNMT1	817.0
H3C1	733.0
H4C11	725.0
H4C5	654.0
H2BC12	519.0
H3C11	416.0
H4C4	162.0
DNMT3L	133.0
H3C8	-350.0
DNMT3B	-2120.0
H4C6	-3817.0
H3C3	-4506.0
H2BC26	-4831.0
H2AC18	-5415.5
H2AC19	-5415.5
H4C13	-6090.0
H2BC14	-7223.0
H2BC13	-7559.0
H2AC14	-7938.0
H4C9	-8005.0

---

REACTOME_COLLAGEN_DEGRADATION

REACTOME_COLLAGEN_DEGRADATION

	108
set	REACTOME_COLLAGEN_DEGRADATION
setSize	61
pANOVA	1.24e-05
s.dist	-0.323
p.adjustANOVA	0.000496

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MMP7	-8911
COL5A1	-8421
COL13A1	-8413
COL6A6	-8274
COL5A2	-8166
MMP20	-7932
MMP3	-7908
COL6A2	-7817
MMP1	-7694
COL7A1	-7631
COL4A4	-7607
MMP15	-7589
COL11A2	-7540
COL6A5	-7445
MMP19	-7378
COL17A1	-7374
MMP12	-7170
COL4A2	-6813
MMP8	-6780
ELANE	-6486

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MMP7	-8911
COL5A1	-8421
COL13A1	-8413
COL6A6	-8274
COL5A2	-8166
MMP20	-7932
MMP3	-7908
COL6A2	-7817
MMP1	-7694
COL7A1	-7631
COL4A4	-7607
MMP15	-7589
COL11A2	-7540
COL6A5	-7445
MMP19	-7378
COL17A1	-7374
MMP12	-7170
COL4A2	-6813
MMP8	-6780
ELANE	-6486
COL23A1	-6393
COL3A1	-5646
COL18A1	-5630
ADAM9	-5469
MMP2	-5346
COL5A3	-4044
MMP13	-4021
COL4A1	-3939
ADAM10	-3906
COL6A1	-3677
COL16A1	-3559
COL8A1	-3145
COL6A3	-3117
COL26A1	-3055
TMPRSS6	-2954
COL14A1	-2593
COL25A1	-2566
MMP14	-2346
MMP9	-2279
CTSB	-1891
COL4A3	-1751
COL12A1	-1678
COL1A2	-1423
COL10A1	-1268
FURIN	-1134
COL15A1	-923
COL1A1	412
PHYKPL	842
COL19A1	1022
COL9A1	1187
COL8A2	1342
COL11A1	1634
ADAM17	1830
MMP11	2982
COL2A1	3703
COL9A2	3989
CTSD	4081
CTSK	5006
MMP10	5121
COL9A3	7370
CTSL	10003

---

REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION

REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION

	1163
set	REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION
setSize	102
pANOVA	1.36e-05
s.dist	0.249
p.adjustANOVA	0.000525

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H3-3A	10816.0
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
CAVIN1	10125.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
H3C12	9726.0
H2BC21	9693.0
H2BC8	9455.0
TAF1A	9448.0
H2AC7	9407.5

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H3-3A	10816.0
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
CAVIN1	10125.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
H3C12	9726.0
H2BC21	9693.0
H2BC8	9455.0
TAF1A	9448.0
H2AC7	9407.5
H2BC7	9407.5
H2AZ1	9026.0
H2AC20	9019.0
POLR1D	8979.0
CCNH	8147.0
H3C4	7677.0
POLR1H	7546.0
GATAD2B	7509.0
CHD3	7459.0
H2BC11	7363.0
H2BC5	7354.0
POLR1A	7174.0
H2BC3	6877.0
CDK7	6742.0
TTF1	6686.0
H4C1	6505.0
POLR1E	6272.0
RBBP4	6026.0
H4C2	5849.0
HDAC2	5842.0
H2AJ	5832.0
H2AX	5821.0
GATAD2A	5679.0
RRN3	5650.0
H4C12	5591.0
CBX3	5436.0
H4C8	5375.0
GTF2H5	5045.0
H3C6	4303.0
MTA3	4233.0
H2AZ2	4022.0
POLR2K	3416.0
HDAC1	3086.0
MTA2	3044.0
H2BC1	2654.0
H3C10	2553.0
POLR1F	2268.0
POLR1G	2079.0
H2BC10	2021.0
GTF2H3	1736.0
MNAT1	1602.0
POLR1B	1577.0
CHD4	1146.0
MBD2	904.0
MAPK3	901.0
TAF1B	887.0
KAT2B	811.0
H3C1	733.0
H4C11	725.0
H4C5	654.0
H2BC12	519.0
POLR2E	455.0
H3C11	416.0
POLR2H	334.0
H4C4	162.0
H3C8	-350.0
GTF2H4	-482.0
POLR2F	-559.0
ERCC2	-1393.0
TBP	-1504.0
ERCC6	-1544.0
ERCC3	-1766.0
TAF1D	-2325.0
UBTF	-2331.0
POLR2L	-3453.0
GTF2H1	-3725.0
H4C6	-3817.0
EHMT2	-3897.0
MBD3	-4382.0
KAT2A	-4470.0
POLR1C	-4475.0
H3C3	-4506.0
H2BC26	-4831.0
H2AC18	-5415.5
H2AC19	-5415.5
H4C13	-6090.0
MTA1	-6195.0
H2BC14	-7223.0
TAF1C	-7464.0
H2BC13	-7559.0
H2AC14	-7938.0
H4C9	-8005.0

---

REACTOME_CHROMOSOME_MAINTENANCE

REACTOME_CHROMOSOME_MAINTENANCE

	1165
set	REACTOME_CHROMOSOME_MAINTENANCE
setSize	130
pANOVA	1.38e-05
s.dist	0.221
p.adjustANOVA	0.000525

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H3-3A	10816.0
H2AC4	10558.0
MIS18A	10519.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H2BC4	9994.0
H2BC9	9978.5
H2BC6	9964.0
H2AC8	9917.0
H2BC21	9693.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
POLR2C	9358.0
H2AZ1	9026.0
H2AC20	9019.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H3-3A	10816.0
H2AC4	10558.0
MIS18A	10519.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H2BC4	9994.0
H2BC9	9978.5
H2BC6	9964.0
H2AC8	9917.0
H2BC21	9693.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
POLR2C	9358.0
H2AZ1	9026.0
H2AC20	9019.0
GAR1	8831.0
TEN1	8743.0
CENPC	8675.0
PCNA	8551.0
DSCC1	8531.0
POLR2G	8490.0
CENPH	8445.0
CENPS	8051.0
POLD4	7923.0
RPA3	7810.0
RPA2	7679.0
DAXX	7619.0
SHQ1	7457.0
CTC1	7412.0
H2BC11	7363.0
H2BC5	7354.0
RFC4	7122.0
POLD1	7018.0
CENPW	7015.0
WRN	6947.0
H2BC3	6877.0
WRAP53	6868.0
CENPA	6857.0
ANKRD28	6566.0
H4C1	6505.0
CENPT	6418.0
CENPM	6270.0
POLD2	6199.0
RBBP4	6026.0
POLR2I	5881.0
BLM	5877.0
H4C2	5849.0
H2AJ	5832.0
H2AX	5821.0
RFC5	5739.0
H4C12	5591.0
H4C8	5375.0
PPP6C	5034.0
POT1	5008.0
NPM1	4661.0
PIF1	4477.0
H2AZ2	4022.0
SMARCA5	3945.0
OIP5	3543.0
ACD	3521.5
POLR2K	3416.0
CDK2	2988.0
DNA2	2805.0
POLR2B	2795.0
KNL1	2766.0
H2BC1	2654.0
PPP6R3	2603.0
RUVBL2	2479.0
TERF2IP	2334.0
LIG1	2069.0
H2BC10	2021.0
RPA1	1885.0
RFC2	1760.0
CENPO	1592.0
POLR2A	1481.0
MIS18BP1	1332.0
RUVBL1	1222.0
CENPQ	1164.0
FEN1	994.0
TERF1	989.0
RFC3	822.0
CCNA1	745.0
H4C11	725.0
H4C5	654.0
H2BC12	519.0
POLR2E	455.0
POLR2H	334.0
H4C4	162.0
POLA2	56.0
CENPL	-455.0
POLR2F	-559.0
RFC1	-815.0
RTEL1	-1361.0
CENPN	-1557.0
STN1	-1566.0
TINF2	-1596.0
POLR2D	-2050.0
HJURP	-2130.0
NOP10	-2457.0
PRIM2	-2930.0
CHTF8	-3309.0
POLR2L	-3453.0
H4C6	-3817.0
NHP2	-4228.0
ITGB3BP	-4330.0
CCNA2	-4363.0
CHTF18	-4677.0
H3-4	-4773.0
H2BC26	-4831.0
CENPU	-4840.0
RSF1	-5031.0
TERF2	-5078.0
H2AC18	-5415.5
H2AC19	-5415.5
CENPK	-5871.0
CENPP	-5908.0
H4C13	-6090.0
POLD3	-7106.0
H2BC14	-7223.0
TERT	-7404.0
H2BC13	-7559.0
PRIM1	-7751.0
H2AC14	-7938.0
H4C9	-8005.0
POLR2J	-10431.0

---

REACTOME_DEUBIQUITINATION

REACTOME_DEUBIQUITINATION

	1000
set	REACTOME_DEUBIQUITINATION
setSize	260
pANOVA	1.47e-05
s.dist	0.156
p.adjustANOVA	0.000547

Top enriched genes

Top 20 genes

GeneID	Gene Rank
AXIN2	11089.0
H2AC21	10743.0
H2AC4	10558.0
H2BC17	10497.0
H2AC15	10342.0
RNF135	10325.0
H2BC15	10314.0
H2AC6	10052.0
PSMD13	10036.0
H2BC4	9994.0
H2BC9	9978.5
H2BC6	9964.0
H2AC16	9919.0
H2AC8	9917.0
BECN1	9905.0
BABAM1	9748.0
H2BC21	9693.0
UCHL5	9667.0
H2BC8	9455.0
ATXN3	9433.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
AXIN2	11089.0
H2AC21	10743.0
H2AC4	10558.0
H2BC17	10497.0
H2AC15	10342.0
RNF135	10325.0
H2BC15	10314.0
H2AC6	10052.0
PSMD13	10036.0
H2BC4	9994.0
H2BC9	9978.5
H2BC6	9964.0
H2AC16	9919.0
H2AC8	9917.0
BECN1	9905.0
BABAM1	9748.0
H2BC21	9693.0
UCHL5	9667.0
H2BC8	9455.0
ATXN3	9433.0
H2AC7	9407.5
H2BC7	9407.5
USP33	9384.0
SNX3	9229.0
H2AC20	9019.0
UBB	8935.0
SMAD7	8777.0
PTRH2	8670.0
TGFBR1	8635.0
PSMA6	8609.0
HIF1A	8488.0
UCHL3	8410.0
H2AC11	8376.0
USP24	8319.0
ABRAXAS1	8286.0
H2AC12	8285.0
BARD1	8265.0
IDE	8248.0
VDAC1	8226.0
H2AC17	8217.0
WDR48	8175.0
PSMC6	8173.0
RNF123	8106.0
USP10	8074.0
TP53	7995.0
VDAC2	7965.0
INO80C	7806.0
SIAH2	7792.0
PSME3	7776.0
ABRAXAS2	7730.0
IFIH1	7675.0
MDM4	7582.0
DDB2	7500.0
SMAD2	7447.0
H2BC11	7363.0
H2BC5	7354.0
FOXK1	7293.0
YOD1	7247.0
NFKBIA	7150.0
SENP8	7131.0
MYC	7102.0
UFD1	7030.0
ACTR5	6904.0
H2BC3	6877.0
OTUB2	6847.0
PSMB3	6752.0
PSMD12	6656.0
RAD23B	6579.0
MAT2B	6573.0
NEDD8	6240.0
USP25	6224.0
PSMB7	6049.0
TGFBR2	5922.0
ESR1	5862.0
TAB1	5840.0
ASXL1	5643.0
BIRC3	5579.0
STAM2	5561.0
CDK1	5463.0
PSMC1	5452.0
TADA2B	5379.0
USP37	5288.0
STAMBPL1	5186.0
USP28	5117.0
PSMD8	5087.0
INO80B	5046.0
FOXK2	4822.0
USP21	4762.0
NOD1	4737.0
PSMB10	4635.0
SUDS3	4594.0
YY1	4593.0
NLRP3	4550.0
MBD6	4469.0
PSMD3	4433.0
APC	4325.0
USP16	4281.0
UCHL1	4266.0
PSMA3	4156.0
USP49	4085.0
TRIM4	4018.0
MCRS1	4010.0
VCPIP1	3876.0
PSMC2	3840.0
USP13	3824.0
TNFAIP3	3730.0
USP4	3640.0
USP7	3536.0
MAP3K7	3513.0
VCP	3474.0
POLB	3419.0
MUL1	3367.0
KEAP1	3287.0
TADA3	3112.0
PSMC5	3099.0
OTUD7A	3066.0
UIMC1	3022.0
ARRB1	3002.0
UBA52	2963.0
PSMB1	2960.0
TNIP3	2935.0
ATXN7	2871.0
SKP2	2789.0
H2BC1	2654.0
PSMB2	2596.0
SMAD1	2562.0
PSMA1	2497.0
PSMB5	2455.0
PSMD2	2443.0
USP22	2432.0
PSMA7	2417.0
PTEN	2393.0
TRAF3	2359.0
BABAM2	2351.0
PSMB4	2281.0
USP3	2267.0
USP15	2252.0
PSMD4	2042.0
H2BC10	2021.0
RHOT1	2005.0
TRRAP	1966.0
USP47	1923.0
SMURF2	1884.0
USP18	1827.0
TFPT	1719.0
USP42	1658.0
PSME1	1571.0
ACTB	1540.0
USP5	1379.0
CYLD	1377.0
PSME2	1245.0
RUVBL1	1222.0
PSMA2	1218.0
RNF146	1184.0
PSMB6	1163.0
SMAD3	1155.0
AXIN1	1098.0
TRAF6	1095.0
KAT2B	811.0
OTUB1	793.0
EP300	777.0
CCNA1	745.0
INO80	736.0
USP44	668.0
MDM2	617.0
USP2	577.0
UBE2D1	557.0
H2BC12	519.0
SEM1	329.0
TAF10	308.0
VDAC3	294.0
CCP110	211.0
SMAD4	194.0
RAD23A	71.0
PSMB8	-53.0
STAMBP	-146.0
USP8	-161.0
BRCA1	-237.0
UBC	-323.0
PSMD5	-411.0
PSMA5	-534.0
TNKS	-689.0
PSMB9	-734.0
PSME4	-771.0
ARRB2	-777.0
PSMD11	-805.0
TRAF2	-1113.0
MAVS	-1222.0
USP34	-1295.0
TGFB1	-1410.0
ACTL6A	-1547.0
RHOA	-1560.0
ADRB2	-1561.0
H2AC1	-1730.0
USP12	-1802.0
PSMD7	-1937.0
INO80E	-1984.0
GATA3	-2179.0
ACTR8	-2201.0
H2AC13	-2215.0
TNIP2	-2298.0
USP14	-2347.0
JOSD2	-2378.0
WDR20	-2382.0
PRKN	-2446.0
TRIM25	-2471.0
BAP1	-2477.0
ASXL2	-2556.0
FKBP8	-2676.0
USP20	-2786.0
USP19	-2879.0
PSMD9	-2906.0
TOMM70	-3021.0
CDC20	-3146.0
TOMM20	-3272.0
NFRKB	-3591.0
OTUD7B	-3702.0
BIRC2	-3812.0
ADRM1	-3884.0
USP48	-4134.0
TNIP1	-4180.0
CCNA2	-4363.0
INO80D	-4392.0
KAT2A	-4470.0
PSMC3	-4492.0
TNKS2	-4557.0
H2BC26	-4831.0
NOD2	-4838.0
STAM	-4909.0
CDC25A	-5146.0
H2AC25	-5226.0
PSMD14	-5297.0
USP30	-5325.0
OTUD3	-5328.0
RIGI	-5371.0
H2AC18	-5415.5
H2AC19	-5415.5
CLSPN	-5454.0
RIPK2	-5497.0
PSMD1	-5508.0
JOSD1	-5615.0
PSMD6	-5633.0
PSMF1	-5638.0
MBD5	-5810.0
ZRANB1	-6178.0
RIPK1	-6194.0
RPS27A	-6484.0
PSMA8	-6587.0
PSMC4	-6643.0
RCE1	-6895.0
H2BC14	-7223.0
PSMA4	-7243.0
IL33	-7391.0
H2BC13	-7559.0
HGS	-7732.0
H2AC14	-7938.0
KDM1B	-8010.0
MYSM1	-8014.0
CFTR	-8973.0
PSMB11	-9711.0

---

REACTOME_PRC2_METHYLATES_HISTONES_AND_DNA

REACTOME_PRC2_METHYLATES_HISTONES_AND_DNA

	440
set	REACTOME_PRC2_METHYLATES_HISTONES_AND_DNA
setSize	65
pANOVA	1.54e-05
s.dist	0.31
p.adjustANOVA	0.000558

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H3-3A	10816.0
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
H3C12	9726.0
H2BC21	9693.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
H2AZ1	9026.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H3-3A	10816.0
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
H3C12	9726.0
H2BC21	9693.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
H2AZ1	9026.0
H2AC20	9019.0
MTF2	7930.0
H3C4	7677.0
H2BC11	7363.0
H2BC5	7354.0
H2BC3	6877.0
H4C1	6505.0
RBBP4	6026.0
JARID2	5998.0
H4C2	5849.0
H2AJ	5832.0
H2AX	5821.0
DNMT3A	5642.0
H4C12	5591.0
H4C8	5375.0
H3C6	4303.0
H2AZ2	4022.0
PHF1	3923.0
H2BC1	2654.0
H3C10	2553.0
H2BC10	2021.0
AEBP2	976.0
DNMT1	817.0
H3C1	733.0
H4C11	725.0
H4C5	654.0
H2BC12	519.0
H3C11	416.0
EZH2	243.0
H4C4	162.0
H3C8	-350.0
PHF19	-475.0
EED	-1311.0
DNMT3B	-2120.0
H4C6	-3817.0
H3C3	-4506.0
H2BC26	-4831.0
SUZ12	-4896.0
H2AC18	-5415.5
H2AC19	-5415.5
H4C13	-6090.0
H2BC14	-7223.0
H2BC13	-7559.0
H2AC14	-7938.0
H4C9	-8005.0

---

REACTOME_RHO_GTPASE_EFFECTORS

REACTOME_RHO_GTPASE_EFFECTORS

	342
set	REACTOME_RHO_GTPASE_EFFECTORS
setSize	305
pANOVA	1.56e-05
s.dist	0.144
p.adjustANOVA	0.000558

Top enriched genes

Top 20 genes

GeneID	Gene Rank
S100A9	11238.0
RAC2	11163.0
H3-3A	10816.0
PPP2R5B	10604.0
H2AC4	10558.0
CDC25C	10524.0
H2BC17	10497.0
TUBB4B	10395.0
CFL1	10391.0
H4C16	10315.0
H2BC15	10314.0
H3-3B	10095.0
H4C3	10086.0
LIMK1	10063.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
S100A9	11238.0
RAC2	11163.0
H3-3A	10816.0
PPP2R5B	10604.0
H2AC4	10558.0
CDC25C	10524.0
H2BC17	10497.0
TUBB4B	10395.0
CFL1	10391.0
H4C16	10315.0
H2BC15	10314.0
H3-3B	10095.0
H4C3	10086.0
LIMK1	10063.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
ACTG1	9958.0
H2AC8	9917.0
FMNL3	9843.0
NSL1	9840.0
RHOQ	9822.0
ARPC1B	9820.0
SGO1	9752.0
H3C12	9726.0
H2BC21	9693.0
MYL12B	9639.0
RHOG	9604.0
BIRC5	9463.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
TUBB6	9322.0
H2AZ1	9026.0
H2AC20	9019.0
RAC1	8876.0
PFN1	8852.0
LIMK2	8803.0
BRK1	8788.0
CENPC	8675.0
ZW10	8484.0
TUBA4B	8469.0
CENPH	8445.0
DYNC1LI2	8336.0
MEN1	8092.0
CENPS	8051.0
TUBA8	8019.0
NUP43	7960.0
PFN2	7934.0
H3C4	7677.0
RHPN2	7655.0
ARPC3	7636.0
NCF2	7558.0
WIPF2	7499.0
TUBB4A	7468.0
PPP2R5A	7419.0
TUBA4A	7384.0
H2BC11	7363.0
S100A8	7358.0
H2BC5	7354.0
ACTR2	7050.0
WIPF1	7048.0
PPP1R14A	6894.0
DYNLL2	6886.0
H2BC3	6877.0
TUBB3	6871.0
CENPA	6857.0
DVL2	6814.0
EVL	6699.0
RHOC	6672.0
CDCA8	6641.0
ACTR3	6639.0
YWHAQ	6594.0
H4C1	6505.0
DYNC1LI1	6419.0
CENPT	6418.0
CDC42	6406.0
NCKAP1	6350.0
ABI1	6343.0
SCAI	6315.0
CENPM	6270.0
NOX3	6209.0
XPO1	5947.0
TAX1BP3	5903.0
H4C2	5849.0
H2AJ	5832.0
H2AX	5821.0
KIF5A	5804.0
PDPK1	5751.0
FMNL1	5708.0
PAK1	5648.0
H4C12	5591.0
ARPC2	5588.0
YWHAH	5488.0
DSN1	5434.0
PPP2R1A	5421.0
CKAP5	5383.0
H4C8	5375.0
TUBB2A	5342.0
TUBA3C	5315.0
ZWILCH	5257.0
MYH9	5185.0
PRKCB	5164.0
ARPC5	5050.0
DLG4	5016.0
KIF14	4767.0
NDE1	4740.0
KIF18A	4714.0
CDKN1B	4666.0
PPP2R5C	4656.0
TAOK1	4538.0
CALM1	4537.0
MYL6	4462.0
RTKN	4389.0
CENPE	4344.0
DYNC1H1	4333.0
AURKB	4328.0
DYNC1I1	4315.0
H3C6	4303.0
H2AZ2	4022.0
WASF2	4008.0
DIAPH1	3804.0
B9D2	3791.0
PMF1	3768.0
DYNC1I2	3671.0
YWHAZ	3670.0
NDC80	3635.0
NUP133	3627.0
CLASP1	3593.0
NUP160	3568.0
SRC	3558.0
WIPF3	3551.0
KIF5B	3535.0
ROCK1	3379.0
PRC1	3337.0
SPC24	3282.0
YWHAG	3187.0
WASF1	3176.0
CLASP2	2994.0
GRB2	2858.0
NCK1	2788.0
KNL1	2766.0
H2BC1	2654.0
GOPC	2617.0
ABL1	2597.0
H3C10	2553.0
WASL	2415.0
DYNLL1	2349.0
SEH1L	2309.0
PLK1	2308.0
PRKCA	2239.0
CYBA	2203.0
H2BC10	2021.0
KLC1	1988.0
PPP1CB	1956.0
PIK3R4	1925.0
PPP2CA	1855.0
BUB1B	1694.0
CENPO	1592.0
KIF2C	1583.0
MRTFA	1554.0
MAPRE1	1549.0
ACTB	1540.0
NUP107	1453.0
MYH10	1415.0
IQGAP1	1280.0
SFN	1261.0
CENPQ	1164.0
TUBB1	1042.0
PKN1	981.0
NUP85	973.0
TUBAL3	971.0
MAPK3	901.0
IQGAP2	841.0
RCC2	742.0
H3C1	733.0
H4C11	725.0
H4C5	654.0
NF2	613.0
MYH14	529.0
H2BC12	519.0
MAD1L1	516.0
NCOA2	417.0
H3C11	416.0
TUBA1B	276.0
PPP1R12A	209.0
H4C4	162.0
PAFAH1B1	139.0
ARPC4	115.0
KLC4	104.0
ROCK2	64.0
DIAPH3	-17.0
ITGB1	-205.0
MIS12	-257.0
H3C8	-350.0
PPP2R1B	-352.0
CENPL	-455.0
KNTC1	-501.0
LIN7B	-600.0
DAAM1	-606.0
PRKCD	-615.0
RPS27	-651.0
BAIAP2	-664.0
MAPK14	-685.0
KDM4C	-803.0
NUP98	-843.0
SGO2	-877.0
CDH1	-945.0
RHPN1	-975.0
CLIP1	-1032.0
NCF4	-1049.0
NOXA1	-1106.0
KLC3	-1108.0
PPP2R5E	-1166.0
PKN2	-1226.0
NDEL1	-1297.0
MYH11	-1388.0
SKA2	-1465.0
IQGAP3	-1477.0
CENPN	-1557.0
RHOA	-1560.0
PPP2R5D	-1720.0
PKN3	-1721.0
KDM1A	-1770.0
MAPK1	-1794.0
PPP1CC	-1885.0
ABI2	-2148.0
RHOB	-2164.0
DVL1	-2230.0
YWHAB	-2453.0
NUDC	-2458.0
KLK3	-2612.0
PRKCZ	-2619.0
PPP1R12B	-2770.0
NUF2	-2839.0
AHCTF1	-3049.0
KTN1	-3050.0
CDC20	-3146.0
PIK3C3	-3214.0
BUB3	-3248.0
SRF	-3253.0
ARPC1A	-3530.0
TUBA1A	-3578.0
MAPK11	-3633.0
BUB1	-3658.0
NCKIPSD	-3742.0
H4C6	-3817.0
TUBA3E	-3827.0
CYFIP2	-3842.0
KLC2	-3925.0
SKA1	-4015.0
TUBA1C	-4095.0
SPDL1	-4219.0
MAD2L1	-4227.0
KIF2B	-4290.0
PIN1	-4308.0
ITGB3BP	-4330.0
H3C3	-4506.0
CIT	-4593.0
CTTN	-4600.0
PPP2CB	-4627.0
YWHAE	-4657.0
CTNNA1	-4777.0
H2BC26	-4831.0
CENPU	-4840.0
TUBA3D	-4880.0
NCKAP1L	-4932.0
SPC25	-4986.0
RANBP2	-5265.0
CTNNB1	-5304.0
NUP37	-5314.0
CENPF	-5361.0
H2AC18	-5415.5
H2AC19	-5415.5
RANGAP1	-5823.0
CENPK	-5871.0
CENPP	-5908.0
FMNL2	-5943.0
H4C13	-6090.0
ZWINT	-6341.0
NOXO1	-6357.0
SEC13	-6814.0
CYFIP1	-6827.0
PAK2	-7196.0
H2BC14	-7223.0
TUBB2B	-7326.0
SRGAP2	-7350.0
KIF2A	-7387.0
WASF3	-7469.0
H2BC13	-7559.0
PTK2	-7586.0
KLK2	-7836.0
H2AC14	-7938.0
DVL3	-8004.0
H4C9	-8005.0
MYL9	-8068.0
INCENP	-8317.0
TUBB8	-8794.0
RHOD	-8912.0
CFTR	-8973.0
MYLK	-8985.0
ROPN1	-10153.0

---

REACTOME_NEUTROPHIL_DEGRANULATION

REACTOME_NEUTROPHIL_DEGRANULATION

	1053
set	REACTOME_NEUTROPHIL_DEGRANULATION
setSize	460
pANOVA	1.75e-05
s.dist	0.117
p.adjustANOVA	0.000613

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TYROBP	11454
PYCARD	11328
S100A9	11238
FCGR3B	11231
RETN	11227
CTSZ	11142
TBC1D10C	11128
BRI3	11009
CD14	10922
FGR	10921
ADGRE5	10860
COMMD3	10850
NIT2	10780
PLAU	10688
HMOX2	10643
TMBIM1	10628
RNASE2	10579
P2RX1	10578
ATP6V0A1	10532
SLC2A3	10470

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TYROBP	11454
PYCARD	11328
S100A9	11238
FCGR3B	11231
RETN	11227
CTSZ	11142
TBC1D10C	11128
BRI3	11009
CD14	10922
FGR	10921
ADGRE5	10860
COMMD3	10850
NIT2	10780
PLAU	10688
HMOX2	10643
TMBIM1	10628
RNASE2	10579
P2RX1	10578
ATP6V0A1	10532
SLC2A3	10470
FCER1G	10466
VAT1	10432
HLA-B	10426
PRDX6	10414
TUBB4B	10395
MANBA	10370
RAB7A	10227
RAB3D	10165
PSMD13	10036
FTH1	10019
ARMC8	9949
KCMF1	9922
GDI2	9888
CEACAM1	9887
SIGLEC14	9886
DOK3	9856
RNASET2	9836
PTGES2	9817
FOLR3	9760
FPR2	9741
KRT1	9728
CD33	9687
RHOG	9604
HSPA8	9600
DEFA4	9598
RAB3A	9566
NRAS	9561
MAN2B1	9544
ORMDL3	9530
STK11IP	9519
ASAH1	9439
RAB14	9410
ADGRE3	9366
B2M	9299
FABP5	9240
GM2A	9235
XRCC6	9095
AMPD3	9081
LAMTOR1	8990
SDCBP	8980
SERPINB6	8955
TMC6	8910
RAP1B	8908
RAC1	8876
PLAC8	8833
LRG1	8703
PNP	8683
GPI	8647
COTL1	8569
ITGB2	8550
IDH1	8546
MIF	8513
STBD1	8499
VAPA	8475
YPEL5	8461
HSPA1B	8434
PKM	8428
KPNB1	8399
CLEC4D	8387
NME2	8381
BIN2	8320
TLR2	8292
TICAM2	8288
FCAR	8201
IMPDH1	8149
CD177	7938
PTPRJ	7882
GMFG	7838
STOM	7624
PAFAH1B2	7607
HSPA1A	7602
UNC13D	7542
GPR84	7466
PLAUR	7377
CD93	7362
S100A8	7358
AGA	7346
GCA	7345
RAP2B	7292
RAB10	7289
TSPAN14	7236
SIGLEC9	7138
CFD	7103
PGLYRP1	7098
ACTR2	7050
CXCR2	6928
AGPAT2	6909
HSP90AB1	6865
SLC11A1	6856
RAB5B	6851
SNAP23	6848
DSP	6839
SLC27A2	6838
ADGRG3	6759
CAND1	6740
SIRPB1	6730
PSMD12	6656
SELL	6644
FUCA2	6556
S100A11	6553
FCGR2A	6539
MCEMP1	6535
PSAP	6531
SERPINB1	6520
DYNC1LI1	6419
AP1M1	6413
HLA-A	6401
DNAJC13	6397
GHDC	6362
LAIR1	6349
CD55	6202
HGSNAT	6200
CSNK2B	6147
IRAG2	6125
CAMP	6066
CYB5R3	6057
PSMB7	6049
CD53	6040
PDXK	6020
LILRA3	5960
EEF1A1	5887
C5AR1	5865
HEBP2	5813
S100P	5634
TRAPPC1	5612
OSTF1	5594
CAPN1	5593
CAT	5586
A1BG	5560
CAP1	5553
RAP1A	5538
ATAD3B	5534
CEACAM6	5505
ARL8A	5437
DSN1	5434
ACTR10	5394
ARHGAP9	5334
SLC44A2	5312
CD58	5310
COMMD9	5255
NFKB1	5242
B4GALT1	5179
DYNLT1	5167
ARPC5	5050
ILF2	5009
LILRB3	4954
SLC15A4	4912
CTSA	4855
CLEC4C	4800
ALDOC	4796
RAB18	4792
HMGB1	4642
GRN	4567
LTF	4485
CHI3L1	4457
PSMD3	4433
ARHGAP45	4419
DYNC1H1	4333
APAF1	4331
DDOST	4181
PGM1	4154
NHLRC3	4148
PSEN1	4110
ALDOA	4083
CTSD	4081
RAB37	3987
TMEM179B	3940
BST1	3843
PSMC2	3840
ALAD	3812
DIAPH1	3804
CNN2	3740
TUBB	3708
CEP290	3693
ARSA	3592
TMEM63A	3529
VCP	3474
LTA4H	3469
QPCT	3432
GOLGA7	3417
PKP1	3395
ROCK1	3379
DNAJC3	3357
NBEAL2	3254
SPTAN1	3207
AGL	3204
HRNR	3149
BPI	3129
CDK13	3106
MME	3101
GSDMD	3089
DEGS1	3024
PSMB1	2960
ANO6	2931
FTL	2901
ATP6V0C	2799
CYSTM1	2780
PRTN3	2749
CD63	2736
UBR4	2712
CD59	2711
OSCAR	2677
CLEC12A	2606
PTPRB	2599
APEH	2598
ACTR1B	2577
PSMD2	2443
TNFAIP6	2420
DYNLL1	2349
GSN	2217
CYBA	2203
SNAP29	2202
STING1	2170
RHOF	2156
PTX3	2133
SCAMP1	2055
ENPP4	2041
PPBP	2007
PRSS3	1996
NPC2	1922
DBNL	1874
VPS35L	1810
NDUFC2	1777
CKAP4	1711
PRCP	1710
CEACAM8	1700
CCT8	1621
GUSB	1593
LAMTOR2	1570
ITGAV	1426
SERPINB3	1425
PGM2	1396
MLEC	1373
IQGAP1	1280
RAB5C	1228
PSMA2	1218
CRISPLD2	1206
CHRNB4	1175
ACLY	1131
SVIP	1061
ERP44	1057
MMP25	1046
HBB	1036
ATP6V1D	988
C6orf120	949
VCL	929
ITGAM	910
IQGAP2	841
TMEM30A	820
OLFM4	784
IST1	783
CD44	779
FGL2	619
HVCN1	497
VNN1	486
PDAP1	469
DPP7	386
CPPED1	261
GAA	186
PRG3	80
CMTM6	74
ADA2	39
CRACR2A	-11
C1orf35	-14
RAB24	-74
GGH	-119
IGF2R	-165
ARSB	-231
MPO	-336
SRP14	-360
LGALS3	-374
TXNDC5	-444
DGAT1	-461
PSMA5	-534
PRKCD	-615
MAPK14	-685
CAB39	-721
ALOX5	-773
PSMD11	-805
RAB27A	-930
ATG7	-959
COPB1	-1058
FUCA1	-1180
GSTP1	-1213
PPIA	-1344
PA2G4	-1455
RHOA	-1560
CD300A	-1573
STK10	-1617
ATP11B	-1649
CD47	-1677
VAMP8	-1697
CR1	-1768
MAPK1	-1794
ACP3	-1803
CTSH	-1819
CTSB	-1891
RAB4B	-1893
PSMD7	-1937
QSOX1	-1962
AP2A2	-2041
PECAM1	-2072
CANT1	-2112
TRPM2	-2199
CCT2	-2210
TCIRG1	-2216
EPX	-2218
HSPA6	-2238
LPCAT1	-2243
TOLLIP	-2246
MMP9	-2279
RAB6A	-2290
PYGL	-2435
NCSTN	-2474
PPIE	-2503
PTAFR	-2508
HLA-C	-2543
GNS	-2675
PLEKHO2	-2678
IMPDH2	-2751
APRT	-2808
TIMP2	-2940
CXCL1	-2948
DNAJC5	-2970
ATP11A	-2979
ACAA1	-3006
PGAM1	-3008
HP	-3029
KCNAB2	-3056
PLD1	-3067
CLEC5A	-3143
GYG1	-3254
PADI2	-3307
NFASC	-3317
CPNE3	-3322
PTPRC	-3375
DERA	-3393
ATP8A1	-3405
CREG1	-3546
SLC2A5	-3689
GALNS	-3713
ADAM8	-3840
ADAM10	-3906
CSTB	-3917
CDA	-3949
HSP90AA1	-4000
XRCC5	-4164
CPNE1	-4174
PYGB	-4236
HEXB	-4271
LAMP1	-4285
TCN1	-4369
ITGAX	-4397
ALDH3B1	-4454
PSMC3	-4492
HK3	-4538
NEU1	-4560
PTPRN2	-4568
C3	-4674
PFKL	-4681
SLPI	-4717
TNFRSF1B	-4816
LCN2	-4843
NCKAP1L	-4932
ANXA2	-5026
PRG2	-5122
MNDA	-5137
GLIPR1	-5159
PSMD14	-5297
ABCA13	-5453
PSMD1	-5508
NFAM1	-5596
PTPN6	-5631
PSMD6	-5633
SERPINB12	-5663
C3AR1	-5671
MS4A3	-5737
CTSC	-5762
RAB31	-5851
ITGAL	-5932
HPSE	-6029
SYNGR1	-6102
MVP	-6160
SERPINA1	-6199
ATP8B4	-6392
TOM1	-6410
ELANE	-6486
SNAP25	-6543
SIGLEC5	-6603
LYZ	-6693
FLG2	-6763
MMP8	-6780
CYFIP1	-6827
SIRPA	-6878
CXCR1	-6910
LAMTOR3	-7041
FRK	-7149
JUP	-7211
OLR1	-7228
BST2	-7263
CRISP3	-7275
SERPINA3	-7388
DSG1	-7415
DOCK2	-7436
SLCO4C1	-7547
CTSS	-7691
FAF2	-7936
CHIT1	-7958
SURF4	-7999
MGST1	-8017
CD68	-8108
NAPRT	-8128
DSC1	-8150
EEF2	-8152
GLB1	-8246
S100A7	-8345
CALML5	-8368
SERPINB10	-8382
TARM1	-8464
MGAM	-8736
PIGR	-8757
ANPEP	-8856
RAB44	-8979
TTR	-9047
CD36	-9061
ORM2	-9095
LILRB2	-9103
ARG1	-9127
CST3	-9147
FPR1	-9153
CEACAM3	-9237
CTSG	-9290
LRRC7	-9349
ORM1	-9488
RNASE3	-9645
FCN1	-9894
AZU1	-9905
AHSG	-9976
AOC1	-10038
S100A12	-10201

---

REACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION

REACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION

	852
set	REACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION
setSize	84
pANOVA	1.99e-05
s.dist	0.269
p.adjustANOVA	0.00068

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H3-3A	10816.0
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
H3C12	9726.0
H2BC21	9693.0
H2BC8	9455.0
TAF1A	9448.0
H2AC7	9407.5
H2BC7	9407.5

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H3-3A	10816.0
H2AC4	10558.0
H2BC17	10497.0
H4C16	10315.0
H2BC15	10314.0
H3-3B	10095.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC8	9917.0
H3C12	9726.0
H2BC21	9693.0
H2BC8	9455.0
TAF1A	9448.0
H2AC7	9407.5
H2BC7	9407.5
H2AZ1	9026.0
H2AC20	9019.0
POLR1D	8979.0
MYO1C	8817.0
H3C4	7677.0
POLR1H	7546.0
DDX21	7483.0
H2BC11	7363.0
H2BC5	7354.0
POLR1A	7174.0
H2BC3	6877.0
H4C1	6505.0
POLR1E	6272.0
H4C2	5849.0
H2AJ	5832.0
H2AX	5821.0
H4C12	5591.0
H4C8	5375.0
DEK	5370.0
BAZ1B	4400.0
H3C6	4303.0
GSK3B	4062.0
H2AZ2	4022.0
SMARCA5	3945.0
POLR2K	3416.0
H2BC1	2654.0
H3C10	2553.0
POLR1F	2268.0
POLR1G	2079.0
H2BC10	2021.0
POLR1B	1577.0
ACTB	1540.0
TAF1B	887.0
KAT2B	811.0
EP300	777.0
H3C1	733.0
H4C11	725.0
H4C5	654.0
H2BC12	519.0
POLR2E	455.0
H3C11	416.0
POLR2H	334.0
H4C4	162.0
H3C8	-350.0
POLR2F	-559.0
SF3B1	-578.0
TBP	-1504.0
ERCC6	-1544.0
TAF1D	-2325.0
MYBBP1A	-2330.0
POLR2L	-3453.0
H4C6	-3817.0
KAT2A	-4470.0
POLR1C	-4475.0
H3C3	-4506.0
H2BC26	-4831.0
H2AC18	-5415.5
H2AC19	-5415.5
H4C13	-6090.0
H2BC14	-7223.0
TAF1C	-7464.0
H2BC13	-7559.0
H2AC14	-7938.0
H4C9	-8005.0

---

REACTOME_HCMV_INFECTION

REACTOME_HCMV_INFECTION

	1463
set	REACTOME_HCMV_INFECTION
setSize	152
pANOVA	2.12e-05
s.dist	0.2
p.adjustANOVA	0.00071

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CHMP4C	11134.0
H2AC21	10743.0
H2AC4	10558.0
H2BC17	10497.0
TUBB4B	10395.0
H2AC15	10342.0
H4C16	10315.0
H2BC15	10314.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC16	9919.0
H2AC8	9917.0
H3C12	9726.0
H2BC21	9693.0
TRIM28	9567.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CHMP4C	11134.0
H2AC21	10743.0
H2AC4	10558.0
H2BC17	10497.0
TUBB4B	10395.0
H2AC15	10342.0
H4C16	10315.0
H2BC15	10314.0
H4C3	10086.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
H2AC16	9919.0
H2AC8	9917.0
H3C12	9726.0
H2BC21	9693.0
TRIM28	9567.0
POM121	9464.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
TUBB6	9322.0
H2AC20	9019.0
VPS37B	8630.0
TUBA4B	8469.0
H2AC11	8376.0
DYNC1LI2	8336.0
H2AC12	8285.0
UBAP1	8258.0
H2AC17	8217.0
RAE1	8059.0
NUP58	8047.0
TUBA8	8019.0
NUP43	7960.0
NUP35	7791.0
NUP50	7744.0
H3C4	7677.0
DAXX	7619.0
TUBB4A	7468.0
TUBA4A	7384.0
H2BC11	7363.0
H2BC5	7354.0
CHMP2A	7210.0
VPS37D	7155.0
CHMP4A	6900.0
DYNLL2	6886.0
H2BC3	6877.0
TUBB3	6871.0
CHMP2B	6780.0
NUP88	6529.0
H4C1	6505.0
DYNC1LI1	6419.0
NUP155	6039.0
RBBP4	6026.0
H4C2	5849.0
CHMP7	5637.0
H4C12	5591.0
H4C8	5375.0
TUBB2A	5342.0
TUBA3C	5315.0
NFKB1	5242.0
VPS4A	5230.0
VPS36	5082.0
HNRNPK	4410.0
DYNC1H1	4333.0
DYNC1I1	4315.0
H3C6	4303.0
GPS2	4260.0
DYNC1I2	3671.0
NUP133	3627.0
NUP160	3568.0
NCOR2	3299.0
NUP214	3289.0
TSG101	3166.0
CHMP3	3159.0
NUP188	2995.0
VPS37C	2839.0
H2BC1	2654.0
H3C10	2553.0
DYNLL1	2349.0
SEH1L	2309.0
H2BC10	2021.0
MVB12B	1947.0
TBL1XR1	1940.0
NUP107	1453.0
POM121C	1147.0
NUP62	1081.0
TUBB1	1042.0
NUP85	973.0
TUBAL3	971.0
H3C1	733.0
PML	732.0
H4C11	725.0
MVB12A	657.0
H4C5	654.0
H2BC12	519.0
H3C11	416.0
TUBA1B	276.0
EZH2	243.0
AAAS	206.0
CBX1	200.0
H4C4	162.0
NUP153	-100.0
ITGB1	-205.0
CREB1	-314.0
H3C8	-350.0
NUP98	-843.0
EED	-1311.0
NUP205	-1359.0
HDAC3	-1583.0
H2AC1	-1730.0
H2AC13	-2215.0
VPS25	-2297.0
NUP210	-2340.0
VPS28	-3361.0
TUBA1A	-3578.0
H4C6	-3817.0
TUBA3E	-3827.0
NCOR1	-3868.0
CHMP1A	-3954.0
TUBA1C	-4095.0
CHMP4B	-4388.0
H3C3	-4506.0
NDC1	-4745.0
SNF8	-4748.0
H2BC26	-4831.0
TUBA3D	-4880.0
SUZ12	-4896.0
NUP42	-5150.0
H2AC25	-5226.0
RANBP2	-5265.0
NUP37	-5314.0
EGFR	-5365.0
H2AC18	-5415.5
H2AC19	-5415.5
NUP93	-5736.0
H4C13	-6090.0
NUP54	-6131.0
VPS37A	-6533.0
CEBPD	-6765.0
SEC13	-6814.0
H2BC14	-7223.0
TUBB2B	-7326.0
CHMP6	-7414.0
H2BC13	-7559.0
H2AC14	-7938.0
H4C9	-8005.0
TPR	-8306.0
TUBB8	-8794.0

---

REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

	1585
set	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3
setSize	679
pANOVA	2.2e-05
s.dist	0.0955
p.adjustANOVA	0.000721

Top enriched genes

Top 20 genes

GeneID	Gene Rank
S100A9	11238
ARHGAP11A	11233
LCK	11223
POTEE	11191
RAC2	11163
ARHGAP11B	11031
PARD6B	10911
CDC42EP1	10887
H3-3A	10816
RHOH	10768
HMOX2	10643
PPP2R5B	10604
FAM169A	10602
PLEKHG2	10587
FAM91A1	10564
H2AC4	10558
ARHGAP30	10549
RAC3	10544
CDC25C	10524
H2BC17	10497

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
S100A9	11238.0
ARHGAP11A	11233.0
LCK	11223.0
POTEE	11191.0
RAC2	11163.0
ARHGAP11B	11031.0
PARD6B	10911.0
CDC42EP1	10887.0
H3-3A	10816.0
RHOH	10768.0
HMOX2	10643.0
PPP2R5B	10604.0
FAM169A	10602.0
PLEKHG2	10587.0
FAM91A1	10564.0
H2AC4	10558.0
ARHGAP30	10549.0
RAC3	10544.0
CDC25C	10524.0
H2BC17	10497.0
CDC42EP5	10483.0
TXNL1	10400.0
TUBB4B	10395.0
CFL1	10391.0
TNFAIP1	10372.0
H4C16	10315.0
H2BC15	10314.0
GRB7	10237.0
RAB7A	10227.0
PGRMC2	10192.0
CAVIN1	10125.0
H3-3B	10095.0
H4C3	10086.0
RND2	10074.0
MTX1	10068.0
LIMK1	10063.0
H2AC6	10052.0
H3C2	10037.0
H2BC4	9994.0
H2BC9	9978.5
H3C7	9978.5
H2BC6	9964.0
GFOD1	9960.0
ACTG1	9958.0
NET1	9944.0
H2AC8	9917.0
ADD3	9862.0
FMNL3	9843.0
NSL1	9840.0
RHOQ	9822.0
ARPC1B	9820.0
AMIGO2	9812.0
PIK3R1	9796.0
SGO1	9752.0
H3C12	9726.0
H2BC21	9693.0
FLOT1	9641.0
MYL12B	9639.0
RHOG	9604.0
ARHGEF25	9578.0
RAP1GDS1	9521.0
BIRC5	9463.0
H2BC8	9455.0
H2AC7	9407.5
H2BC7	9407.5
TUBB6	9322.0
EPSTI1	9271.0
ALS2	9250.0
CSK	9222.0
RHOV	9207.0
ARHGAP27	9205.0
H2AZ1	9026.0
H2AC20	9019.0
LAMTOR1	8990.0
PTK2B	8939.0
RAC1	8876.0
PFN1	8852.0
RHOBTB3	8841.0
SHKBP1	8829.0
LIMK2	8803.0
FAM13B	8795.0
BRK1	8788.0
CENPC	8675.0
RHOU	8587.0
HINT2	8575.0
PRAG1	8542.0
TMEM59	8535.0
COPS4	8519.0
STBD1	8499.0
ZW10	8484.0
TUBA4B	8469.0
CENPH	8445.0
DYNC1LI2	8336.0
ABCD3	8299.0
ARHGDIG	8219.0
CEP97	8177.0
SWAP70	8141.0
MEN1	8092.0
ARHGEF2	8061.0
CENPS	8051.0
GJA1	8038.0
TUBA8	8019.0
NUP43	7960.0
PFN2	7934.0
ANLN	7878.0
ARHGDIB	7852.0
STK38	7807.0
RBBP6	7765.0
H3C4	7677.0
RHPN2	7655.0
ARPC3	7636.0
STOM	7624.0
NCF2	7558.0
WIPF2	7499.0
TUBB4A	7468.0
DOCK9	7461.0
PPP2R5A	7419.0
ABL2	7399.0
TUBA4A	7384.0
H2BC11	7363.0
S100A8	7358.0
H2BC5	7354.0
CPSF7	7303.0
SLITRK5	7196.0
CDC37	7104.0
ANKRD26	7081.0
KCTD13	7064.0
ACTR2	7050.0
WIPF1	7048.0
LRRC41	7036.0
RND1	6946.0
ARHGAP17	6898.0
PPP1R14A	6894.0
DYNLL2	6886.0
H2BC3	6877.0
TUBB3	6871.0
HSP90AB1	6865.0
ARAP1	6864.0
CENPA	6857.0
SNAP23	6848.0
DSP	6839.0
DVL2	6814.0
EFHD2	6715.0
EVL	6699.0
RHOC	6672.0
CDCA8	6641.0
ACTR3	6639.0
BCR	6607.0
YWHAQ	6594.0
RHOBTB2	6572.0
EMC3	6563.0
H4C1	6505.0
STX5	6504.0
RNF20	6494.0
UBXN11	6453.0
ALDH3A2	6428.0
DYNC1LI1	6419.0
CENPT	6418.0
CDC42	6406.0
GNA13	6394.0
NCKAP1	6350.0
ABI1	6343.0
SCAI	6315.0
PREX1	6304.0
CENPM	6270.0
NOX3	6209.0
SYDE1	6148.0
PIK3R2	6055.0
TMOD3	5992.0
PTPN13	5973.0
XPO1	5947.0
TAX1BP3	5903.0
STIP1	5861.0
H4C2	5849.0
H2AJ	5832.0
H2AX	5821.0
KIF5A	5804.0
PDPK1	5751.0
DBN1	5743.0
FMNL1	5708.0
VRK2	5692.0
EPHA2	5659.0
PAK1	5648.0
H4C12	5591.0
ARPC2	5588.0
STAM2	5561.0
CDC42EP2	5523.0
YWHAH	5488.0
DSN1	5434.0
PPP2R1A	5421.0
WDR6	5402.0
CKAP5	5383.0
H4C8	5375.0
TUBB2A	5342.0
ARHGAP9	5334.0
TUBA3C	5315.0
NSFL1C	5274.0
ZWILCH	5257.0
MYH9	5185.0
PRKCB	5164.0
CUL3	5141.0
ARHGAP40	5092.0
FLOT2	5072.0
ARPC5	5050.0
TRAK2	5039.0
DLG4	5016.0
PHIP	4947.0
ARHGEF3	4890.0
SPEN	4882.0
FNBP1	4878.0
ARHGEF4	4848.0
FAM13A	4845.0
SAMM50	4812.0
KIF14	4767.0
NDE1	4740.0
MYO9B	4717.0
KIF18A	4714.0
CDKN1B	4666.0
PPP2R5C	4656.0
LRRC1	4634.0
LMAN1	4618.0
TAOK1	4538.0
CALM1	4537.0
RRAS2	4528.0
PLD2	4505.0
MAP3K11	4504.0
MYL6	4462.0
ARHGAP45	4419.0
ARHGAP29	4406.0
RTKN	4389.0
DSG2	4366.0
CENPE	4344.0
DYNC1H1	4333.0
AURKB	4328.0
DYNC1I1	4315.0
H3C6	4303.0
CCT7	4274.0
ARHGEF39	4218.0
PLEKHG6	4120.0
ECT2	4119.0
H2AZ2	4022.0
WASF2	4008.0
MACO1	3979.0
TRA2B	3975.0
FGD3	3917.0
TOR1AIP1	3915.0
CCDC115	3818.0
GIT1	3805.0
DIAPH1	3804.0
B9D2	3791.0
PMF1	3768.0
DOCK10	3725.0
PEAK1	3681.0
ARHGAP19	3673.0
DYNC1I2	3671.0
YWHAZ	3670.0
NDC80	3635.0
NUP133	3627.0
CLASP1	3593.0
RHOBTB1	3581.0
NDUFS3	3570.0
NUP160	3568.0
SRC	3558.0
WIPF3	3551.0
KIF5B	3535.0
PARD6A	3521.5
MYO9A	3493.0
VCP	3474.0
JAG1	3381.0
ROCK1	3379.0
PRC1	3337.0
PLXND1	3322.0
SPC24	3282.0
SPTAN1	3207.0
YWHAG	3187.0
WASF1	3176.0
HSPE1	3153.0
SOS2	3113.0
SH3BP1	3060.0
CLASP2	2994.0
VAV1	2979.0
ARHGAP18	2913.0
VAV3	2908.0
COPS2	2870.0
GRB2	2858.0
ARHGAP44	2797.0
NCK1	2788.0
C1QBP	2784.0
KNL1	2766.0
RALGAPA1	2741.0
H2BC1	2654.0
LBR	2649.0
GOPC	2617.0
ABL1	2597.0
CHN2	2588.0
H3C10	2553.0
FARP2	2512.0
ACTC1	2487.0
UACA	2439.0
WASL	2415.0
TMEM87A	2410.0
DYNLL1	2349.0
AKAP12	2336.0
SEH1L	2309.0
PLK1	2308.0
DDX4	2296.0
PLEKHG5	2292.0
PRKCA	2239.0
MCAM	2206.0
CYBA	2203.0
RHOF	2156.0
ARHGAP10	2087.0
VAMP3	2037.0
H2BC10	2021.0
RHOT1	2005.0
KLC1	1988.0
PPP1CB	1956.0
PIK3R4	1925.0
ARHGAP25	1890.0
AKAP13	1882.0
ELMO2	1880.0
PPP2CA	1855.0
ESYT1	1800.0
CLTC	1791.0
MYO19	1773.0
DOCK8	1744.0
CKAP4	1711.0
BUB1B	1694.0
TRAK1	1693.0
CAV1	1619.0
SHMT2	1606.0
MFN2	1600.0
CENPO	1592.0
KIF2C	1583.0
MRTFA	1554.0
MAPRE1	1549.0
ACTB	1540.0
NUP107	1453.0
MSI2	1450.0
MYH10	1415.0
GIT2	1353.0
FNBP1L	1348.0
SYDE2	1296.0
IQGAP1	1280.0
WDR91	1275.0
TWF1	1269.0
SFN	1261.0
SENP1	1260.0
SPATA13	1258.0
TIAM1	1251.0
CENPQ	1164.0
YKT6	1119.0
ERBIN	1112.0
ARHGAP15	1077.0
TUBB1	1042.0
PKN1	981.0
TRIP10	977.0
NUP85	973.0
TUBAL3	971.0
TAGAP	942.0
RND3	933.0
MAPK3	901.0
ARFGAP3	870.0
DEPDC1B	867.0
SLITRK3	854.0
IQGAP2	841.0
ARHGEF16	807.0
LEMD3	798.0
RACGAP1	792.0
FILIP1	785.0
RCC2	742.0
H3C1	733.0
H4C11	725.0
STMN2	722.0
H4C5	654.0
NF2	613.0
MYO6	591.0
MYH14	529.0
H2BC12	519.0
MAD1L1	516.0
ARHGEF12	509.0
ARHGEF7	445.0
DNMBP	434.0
SCRIB	433.0
NCOA2	417.0
H3C11	416.0
RASGRF2	410.0
CHN1	400.0
NIPSNAP2	399.0
WWP2	318.0
VANGL2	306.0
TUBA1B	276.0
FRS3	256.0
CCP110	211.0
PPP1R12A	209.0
AAAS	206.0
H4C4	162.0
ARAP2	161.0
WDR11	147.0
PAFAH1B1	139.0
PDE5A	132.0
TFRC	119.0
ARPC4	115.0
FAM135A	109.0
KLC4	104.0
SPTBN1	93.0
ROCK2	64.0
DBT	57.0
NDUFA5	8.0
DIAPH3	-17.0
ARHGAP31	-38.0
ITGB1	-205.0
GARRE1	-224.0
MIS12	-257.0
LETM1	-276.0
TPM4	-322.0
VHL	-326.0
H3C8	-350.0
PPP2R1B	-352.0
CENPL	-455.0
MPP7	-466.0
CAPZB	-478.0
KNTC1	-501.0
ARHGAP21	-536.0
PAK5	-563.0
VANGL1	-586.0
PLIN3	-595.0
LIN7B	-600.0
DAAM1	-606.0
PRKCD	-615.0
ARHGEF5	-626.0
RPS27	-651.0
BAIAP2	-664.0
ACTN1	-671.0
MAPK14	-685.0
ANKLE2	-687.0
SH3PXD2A	-692.0
CDC42EP3	-700.0
PKP4	-709.0
TAOK3	-802.0
KDM4C	-803.0
PIK3CA	-820.0
NUP98	-843.0
SOS1	-853.0
SGO2	-877.0
ARHGEF26	-922.0
CDH1	-945.0
RHPN1	-975.0
BLTP3B	-989.0
SLK	-992.0
CLIP1	-1032.0
NCF4	-1049.0
RAPGEF1	-1081.0
NOXA1	-1106.0
KLC3	-1108.0
KIDINS220	-1124.0
PPP2R5E	-1166.0
ARHGAP20	-1171.0
GOLGA3	-1179.0
ITSN2	-1223.0
PKN2	-1226.0
ARHGEF40	-1229.0
NDEL1	-1297.0
ARHGAP26	-1383.0
MYH11	-1388.0
ARHGAP42	-1398.0
SKA2	-1465.0
IQGAP3	-1477.0
DOCK6	-1520.0
WHAMM	-1528.0
CENPN	-1557.0
RHOA	-1560.0
STK10	-1617.0
DOCK7	-1636.0
VAPB	-1644.0
PPP2R5D	-1720.0
PKN3	-1721.0
CDC42BPB	-1732.0
KDM1A	-1770.0
MAPK1	-1794.0
ARHGEF10	-1815.0
PPP1CC	-1885.0
ABR	-1926.0
ARHGAP5	-1976.0
MFN1	-1995.0
SRRM1	-2077.0
FRS2	-2087.0
TJP2	-2098.0
ABI2	-2148.0
RHOB	-2164.0
FGD4	-2204.0
CCT2	-2210.0
DVL1	-2230.0
ZAP70	-2268.0
ARHGDIA	-2281.0
SOWAHC	-2367.0
TEX2	-2377.0
YWHAB	-2453.0
NUDC	-2458.0
PIK3R3	-2501.0
ARFGAP2	-2544.0
SCFD1	-2585.0
BAIAP2L1	-2598.0
KLK3	-2612.0
PRKCZ	-2619.0
PLXNB1	-2634.0
PICALM	-2718.0
ARAP3	-2742.0
HTR7	-2765.0
PPP1R12B	-2770.0
ARHGAP12	-2777.0
NUF2	-2839.0
PLEKHG1	-2999.0
ANKFY1	-3034.0
RALBP1	-3036.0
AHCTF1	-3049.0
KTN1	-3050.0
PLD1	-3067.0
RASAL2	-3072.0
GPS1	-3122.0
CDC20	-3146.0
CPD	-3168.0
ARHGEF18	-3181.0
CDC42BPA	-3182.0
PIK3C3	-3214.0
BUB3	-3248.0
SRF	-3253.0
DOCK3	-3261.0
CKB	-3266.0
LMNB1	-3282.0
WDR81	-3323.0
ACBD5	-3353.0
TPM3	-3422.0
ARHGEF1	-3511.0
ARPC1A	-3530.0
VAV2	-3550.0
TUBA1A	-3578.0
NGEF	-3587.0
MCF2L	-3600.0
CDC42SE2	-3621.0
MAPK11	-3633.0
BUB1	-3658.0
DDX39B	-3686.0
NCKIPSD	-3742.0
VIM	-3752.0
PREX2	-3786.0
DLC1	-3814.0
H4C6	-3817.0
TUBA3E	-3827.0
CYFIP2	-3842.0
KLC2	-3925.0
HSP90AA1	-4000.0
SKA1	-4015.0
CDC42EP4	-4020.0
ITSN1	-4060.0
TUBA1C	-4095.0
ARHGAP39	-4165.0
SH3RF1	-4197.0
SPDL1	-4219.0
MAD2L1	-4227.0
KIF2B	-4290.0
PIN1	-4308.0
ITGB3BP	-4330.0
ARHGEF15	-4374.0
NISCH	-4464.0
CPNE8	-4496.0
H3C3	-4506.0
PLEKHG3	-4511.0
FERMT2	-4517.0
CIT	-4593.0
CTTN	-4600.0
PPP2CB	-4627.0
BASP1	-4649.0
YWHAE	-4657.0
HNRNPC	-4690.0
DST	-4764.0
CTNNA1	-4777.0
H2BC26	-4831.0
CENPU	-4840.0
ARHGAP35	-4879.0
TUBA3D	-4880.0
STAM	-4909.0
NCKAP1L	-4932.0
PCDH7	-4980.0
SPC25	-4986.0
ARHGAP1	-5045.0
CCDC88A	-5174.0
DOCK4	-5211.0
ARHGEF28	-5215.0
ARL13B	-5238.0
RANBP2	-5265.0
CTNNB1	-5304.0
NUP37	-5314.0
CENPF	-5361.0
MTR	-5411.0
H2AC18	-5415.5
H2AC19	-5415.5
TMPO	-5468.0
CCT6A	-5546.0
SLC4A7	-5594.0
RHOJ	-5687.0
FGD2	-5783.0
RANGAP1	-5823.0
DEF6	-5827.0
CENPK	-5871.0
CENPP	-5908.0
SLC1A5	-5911.0
TIAM2	-5933.0
FMNL2	-5943.0
OSBPL11	-5977.0
ARHGEF11	-5980.0
IL32	-6048.0
H4C13	-6090.0
SRGAP3	-6250.0
PAK6	-6273.0
PAK4	-6323.0
ZWINT	-6341.0
NOXO1	-6357.0
NCK2	-6432.0
OBSCN	-6434.0
DOCK1	-6494.0
ARHGEF17	-6507.0
SRGAP1	-6609.0
SEC13	-6814.0
ARHGAP22	-6819.0
CYFIP1	-6827.0
DDRGK1	-6949.0
DLG5	-7021.0
KCTD3	-7054.0
PAK2	-7196.0
JUP	-7211.0
H2BC14	-7223.0
FARP1	-7302.0
BAIAP2L2	-7303.0
TUBB2B	-7326.0
SRGAP2	-7350.0
KIF2A	-7387.0
DSG1	-7415.0
DOCK2	-7436.0
WASF3	-7469.0
ARHGAP24	-7474.0
H2BC13	-7559.0
PLEKHG4B	-7580.0
PTK2	-7586.0
ARHGAP33	-7593.0
FAM83B	-7633.0
DOCK5	-7655.0
HGS	-7732.0
KLK2	-7836.0
CCNE1	-7855.0
ARHGAP8	-7899.0
ARHGEF10L	-7919.0
TRIO	-7926.0
FAF2	-7936.0
H2AC14	-7938.0
ARHGAP28	-7964.0
DVL3	-8004.0
H4C9	-8005.0
PLXNA1	-8067.0
MYL9	-8068.0
ZNF512B	-8098.0
STARD13	-8223.0
INCENP	-8317.0
SEMA4F	-8360.0
KALRN	-8375.0
RHOT2	-8551.0
TUBB8	-8794.0
RHOD	-8912.0
CFTR	-8973.0
MYLK	-8985.0
ARHGAP32	-9154.0
GMIP	-9282.0
PLEKHG4	-9298.0
ARHGAP23	-9314.0
FGD5	-9333.0
STEAP3	-9426.0
ARHGEF19	-9594.0
MUC13	-10051.0
ROPN1	-10153.0

---

Here is the session info with all the versions of packages used.

sessionInfo()

## R version 4.3.2 (2023-10-31)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.3 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3 
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so;  LAPACK version 3.10.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Etc/UTC
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.3.3                                      
##  [2] GGally_2.2.0                                       
##  [3] ggplot2_3.4.4                                      
##  [4] reshape2_1.4.4                                     
##  [5] gtools_3.9.5                                       
##  [6] tibble_3.2.1                                       
##  [7] dplyr_1.1.4                                        
##  [8] echarts4r_0.4.5                                    
##  [9] png_0.1-8                                          
## [10] gridExtra_2.3                                      
## [11] missMethyl_1.36.0                                  
## [12] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.1 
## [13] beeswarm_0.4.0                                     
## [14] kableExtra_1.3.4                                   
## [15] gplots_3.1.3                                       
## [16] mitch_1.15.0                                       
## [17] tictoc_1.2                                         
## [18] HGNChelper_0.8.1                                   
## [19] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [20] IlluminaHumanMethylation450kmanifest_0.4.0         
## [21] minfi_1.48.0                                       
## [22] bumphunter_1.44.0                                  
## [23] locfit_1.5-9.8                                     
## [24] iterators_1.0.14                                   
## [25] foreach_1.5.2                                      
## [26] Biostrings_2.70.1                                  
## [27] XVector_0.42.0                                     
## [28] SummarizedExperiment_1.32.0                        
## [29] Biobase_2.62.0                                     
## [30] MatrixGenerics_1.14.0                              
## [31] matrixStats_1.2.0                                  
## [32] GenomicRanges_1.54.1                               
## [33] GenomeInfoDb_1.38.2                                
## [34] IRanges_2.36.0                                     
## [35] S4Vectors_0.40.2                                   
## [36] BiocGenerics_0.48.1                                
## [37] eulerr_7.0.0                                       
## [38] limma_3.58.1                                       
## 
## loaded via a namespace (and not attached):
##   [1] splines_4.3.2             later_1.3.2              
##   [3] BiocIO_1.12.0             bitops_1.0-7             
##   [5] filelock_1.0.3            preprocessCore_1.64.0    
##   [7] XML_3.99-0.16             lifecycle_1.0.4          
##   [9] lattice_0.22-5            MASS_7.3-60              
##  [11] base64_2.0.1              scrime_1.3.5             
##  [13] magrittr_2.0.3            sass_0.4.8               
##  [15] rmarkdown_2.25            jquerylib_0.1.4          
##  [17] yaml_2.3.8                httpuv_1.6.13            
##  [19] doRNG_1.8.6               askpass_1.2.0            
##  [21] DBI_1.1.3                 RColorBrewer_1.1-3       
##  [23] abind_1.4-5               zlibbioc_1.48.0          
##  [25] rvest_1.0.3               quadprog_1.5-8           
##  [27] purrr_1.0.2               RCurl_1.98-1.13          
##  [29] rappdirs_0.3.3            GenomeInfoDbData_1.2.11  
##  [31] genefilter_1.84.0         annotate_1.80.0          
##  [33] svglite_2.1.3             DelayedMatrixStats_1.24.0
##  [35] codetools_0.2-19          DelayedArray_0.28.0      
##  [37] xml2_1.3.6                tidyselect_1.2.0         
##  [39] beanplot_1.3.1            BiocFileCache_2.10.1     
##  [41] webshot_0.5.5             illuminaio_0.44.0        
##  [43] GenomicAlignments_1.38.0  jsonlite_1.8.8           
##  [45] multtest_2.58.0           ellipsis_0.3.2           
##  [47] survival_3.5-7            systemfonts_1.0.5        
##  [49] tools_4.3.2               progress_1.2.3           
##  [51] Rcpp_1.0.11               glue_1.6.2               
##  [53] SparseArray_1.2.2         xfun_0.41                
##  [55] HDF5Array_1.30.0          withr_2.5.2              
##  [57] fastmap_1.1.1             rhdf5filters_1.14.1      
##  [59] fansi_1.0.6               openssl_2.1.1            
##  [61] caTools_1.18.2            digest_0.6.33            
##  [63] R6_2.5.1                  mime_0.12                
##  [65] colorspace_2.1-0          biomaRt_2.58.0           
##  [67] RSQLite_2.3.4             utf8_1.2.4               
##  [69] tidyr_1.3.0               generics_0.1.3           
##  [71] data.table_1.14.10        rtracklayer_1.62.0       
##  [73] prettyunits_1.2.0         httr_1.4.7               
##  [75] htmlwidgets_1.6.4         S4Arrays_1.2.0           
##  [77] ggstats_0.5.1             pkgconfig_2.0.3          
##  [79] gtable_0.3.4              blob_1.2.4               
##  [81] siggenes_1.76.0           htmltools_0.5.7          
##  [83] scales_1.3.0              rstudioapi_0.15.0        
##  [85] knitr_1.45                tzdb_0.4.0               
##  [87] rjson_0.2.21              nlme_3.1-163             
##  [89] curl_5.2.0                org.Hs.eg.db_3.18.0      
##  [91] cachem_1.0.8              rhdf5_2.46.1             
##  [93] stringr_1.5.1             KernSmooth_2.23-22       
##  [95] AnnotationDbi_1.64.1      restfulr_0.0.15          
##  [97] GEOquery_2.70.0           pillar_1.9.0             
##  [99] grid_4.3.2                reshape_0.8.9            
## [101] vctrs_0.6.5               promises_1.2.1           
## [103] dbplyr_2.4.0              xtable_1.8-4             
## [105] evaluate_0.23             readr_2.1.4              
## [107] GenomicFeatures_1.54.1    cli_3.6.2                
## [109] compiler_4.3.2            Rsamtools_2.18.0         
## [111] rlang_1.1.2               crayon_1.5.2             
## [113] rngtools_1.5.2            nor1mix_1.3-2            
## [115] mclust_6.0.1              plyr_1.8.9               
## [117] stringi_1.8.3             viridisLite_0.4.2        
## [119] BiocParallel_1.36.0       munsell_0.5.0            
## [121] Matrix_1.6-1.1            hms_1.1.3                
## [123] sparseMatrixStats_1.14.0  bit64_4.0.5              
## [125] Rhdf5lib_1.24.1           KEGGREST_1.42.0          
## [127] statmod_1.5.0             shiny_1.8.0              
## [129] highr_0.10                memoise_2.0.1            
## [131] bslib_0.6.1               bit_4.0.5

END of report