Mitch Report

date generated: 2024-01-18

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch

	x
A1BG	-0.0005964
A1BG-AS1	-0.0007591
A1CF	0.0008361
A2M	0.0000134
A2M-AS1	-0.0015791
A2ML1	0.0000398

Here are some metrics about the input data profile:

Profiling data metrics

	Profile metrics
num_genesets	1654
num_genes_in_profile	22007
duplicated_genes_present	0
num_profile_genes_in_sets	10383
num_profile_genes_not_in_sets	11624

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets: c2.cp.reactome.v2023.1.Hs.symbols.gmt

Gene set metrics

	Gene sets metrics
num_genesets	1654
num_genesets_excluded	365
num_genesets_included	1289

Differential pathway expression

Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

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## in kable. kableExtra can customize either HTML or LaTeX outputs. See
## https://haozhu233.github.io/kableExtra/ for details.

set	setSize	pANOVA	s.dist	p.adjustANOVA
REACTOME OLFACTORY SIGNALING PATHWAY	348	2.57e-14	0.2380	4.23e-11
REACTOME SENSORY PERCEPTION	555	6.37e-09	0.1440	5.23e-06
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS	161	4.53e-08	0.2500	2.48e-05
REACTOME EUKARYOTIC TRANSLATION ELONGATION	87	5.60e-07	0.3100	2.08e-04
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	105	6.34e-07	0.2810	2.08e-04
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY	94	1.03e-06	0.2920	2.48e-04
REACTOME RRNA PROCESSING	192	1.06e-06	0.2040	2.48e-04
REACTOME RNA POLYMERASE I PROMOTER ESCAPE	83	1.88e-06	0.3030	3.57e-04
REACTOME SIGNALING BY ROBO RECEPTORS	206	1.96e-06	0.1920	3.57e-04
REACTOME EUKARYOTIC TRANSLATION INITIATION	110	2.92e-06	0.2580	4.80e-04
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS	121	5.11e-06	0.2400	7.62e-04
REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION	60	6.28e-06	0.3370	8.59e-04
REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION	100	7.92e-06	0.2580	1.00e-03
REACTOME METABOLISM OF RNA	675	1.06e-05	0.0994	1.25e-03
REACTOME TRANSLATION	278	1.19e-05	0.1530	1.31e-03
REACTOME NONSENSE MEDIATED DECAY NMD	107	1.32e-05	0.2440	1.36e-03
REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION	84	1.82e-05	0.2700	1.75e-03
REACTOME AMYLOID FIBER FORMATION	102	2.68e-05	0.2410	2.34e-03
REACTOME SELENOAMINO ACID METABOLISM	108	2.71e-05	0.2340	2.34e-03
REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3	59	3.11e-05	0.3130	2.55e-03
REACTOME DNA METHYLATION	58	4.64e-05	0.3090	3.57e-03
REACTOME PRC2 METHYLATES HISTONES AND DNA	65	4.78e-05	0.2920	3.57e-03
REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	123	7.30e-05	-0.2070	5.21e-03
REACTOME PASSIVE TRANSPORT BY AQUAPORINS	13	9.28e-05	-0.6260	6.35e-03
REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	111	1.01e-04	0.2140	6.62e-03
REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION	62	1.19e-04	0.2820	7.53e-03
REACTOME RNA POLYMERASE II TRANSCRIPTION	1336	1.29e-04	0.0624	7.86e-03
REACTOME CELLULAR RESPONSE TO STARVATION	147	1.55e-04	0.1810	8.70e-03
REACTOME DISEASES OF PROGRAMMED CELL DEATH	96	1.58e-04	0.2230	8.70e-03
REACTOME AQUAPORIN MEDIATED TRANSPORT	51	1.59e-04	-0.3060	8.70e-03
REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT	222	2.09e-04	0.1440	1.11e-02
REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT	159	2.22e-04	0.1700	1.14e-02
REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION	98	2.68e-04	0.2130	1.33e-02
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION	138	3.58e-04	0.1760	1.71e-02
REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE	63	3.64e-04	0.2600	1.71e-02
REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS	100	4.03e-04	0.2050	1.79e-02
REACTOME INFLUENZA INFECTION	149	4.04e-04	0.1680	1.79e-02
REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION	68	4.16e-04	0.2470	1.80e-02
REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS	63	4.69e-04	0.2550	1.93e-02
REACTOME RNA POLYMERASE I TRANSCRIPTION	102	4.69e-04	0.2000	1.93e-02
REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX	85	4.87e-04	0.2190	1.95e-02
REACTOME RESPIRATORY ELECTRON TRANSPORT	90	5.61e-04	0.2100	2.19e-02
REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS	60	6.38e-04	0.2550	2.39e-02
REACTOME BETA DEFENSINS	27	6.40e-04	0.3800	2.39e-02
REACTOME DEVELOPMENTAL BIOLOGY	1115	9.03e-04	0.0589	3.30e-02
REACTOME DEFENSINS	33	9.40e-04	0.3330	3.36e-02
REACTOME RHO GTPASES ACTIVATE PKNS	86	9.61e-04	0.2060	3.36e-02
REACTOME DNA REPLICATION PRE INITIATION	150	1.04e-03	0.1550	3.52e-02
REACTOME HDACS DEACETYLATE HISTONES	85	1.05e-03	0.2060	3.52e-02
REACTOME PHOSPHOLIPID METABOLISM	201	1.20e-03	-0.1320	3.95e-02

---

Results (complete table)

Click HERE to show results for all gene sets

Complete results

set	setSize	pANOVA	s.dist	p.adjustANOVA
REACTOME OLFACTORY SIGNALING PATHWAY	348	2.57e-14	2.38e-01	4.23e-11
REACTOME SENSORY PERCEPTION	555	6.37e-09	1.44e-01	5.23e-06
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS	161	4.53e-08	2.50e-01	2.48e-05
REACTOME EUKARYOTIC TRANSLATION ELONGATION	87	5.60e-07	3.10e-01	2.08e-04
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	105	6.34e-07	2.81e-01	2.08e-04
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY	94	1.03e-06	2.92e-01	2.48e-04
REACTOME RRNA PROCESSING	192	1.06e-06	2.04e-01	2.48e-04
REACTOME RNA POLYMERASE I PROMOTER ESCAPE	83	1.88e-06	3.03e-01	3.57e-04
REACTOME SIGNALING BY ROBO RECEPTORS	206	1.96e-06	1.92e-01	3.57e-04
REACTOME EUKARYOTIC TRANSLATION INITIATION	110	2.92e-06	2.58e-01	4.80e-04
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS	121	5.11e-06	2.40e-01	7.62e-04
REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION	60	6.28e-06	3.37e-01	8.59e-04
REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION	100	7.92e-06	2.58e-01	1.00e-03
REACTOME METABOLISM OF RNA	675	1.06e-05	9.94e-02	1.25e-03
REACTOME TRANSLATION	278	1.19e-05	1.53e-01	1.31e-03
REACTOME NONSENSE MEDIATED DECAY NMD	107	1.32e-05	2.44e-01	1.36e-03
REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION	84	1.82e-05	2.70e-01	1.75e-03
REACTOME AMYLOID FIBER FORMATION	102	2.68e-05	2.41e-01	2.34e-03
REACTOME SELENOAMINO ACID METABOLISM	108	2.71e-05	2.34e-01	2.34e-03
REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3	59	3.11e-05	3.13e-01	2.55e-03
REACTOME DNA METHYLATION	58	4.64e-05	3.09e-01	3.57e-03
REACTOME PRC2 METHYLATES HISTONES AND DNA	65	4.78e-05	2.92e-01	3.57e-03
REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	123	7.30e-05	-2.07e-01	5.21e-03
REACTOME PASSIVE TRANSPORT BY AQUAPORINS	13	9.28e-05	-6.26e-01	6.35e-03
REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	111	1.01e-04	2.14e-01	6.62e-03
REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION	62	1.19e-04	2.82e-01	7.53e-03
REACTOME RNA POLYMERASE II TRANSCRIPTION	1336	1.29e-04	6.24e-02	7.86e-03
REACTOME CELLULAR RESPONSE TO STARVATION	147	1.55e-04	1.81e-01	8.70e-03
REACTOME DISEASES OF PROGRAMMED CELL DEATH	96	1.58e-04	2.23e-01	8.70e-03
REACTOME AQUAPORIN MEDIATED TRANSPORT	51	1.59e-04	-3.06e-01	8.70e-03
REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT	222	2.09e-04	1.44e-01	1.11e-02
REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT	159	2.22e-04	1.70e-01	1.14e-02
REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION	98	2.68e-04	2.13e-01	1.33e-02
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION	138	3.58e-04	1.76e-01	1.71e-02
REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE	63	3.64e-04	2.60e-01	1.71e-02
REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS	100	4.03e-04	2.05e-01	1.79e-02
REACTOME INFLUENZA INFECTION	149	4.04e-04	1.68e-01	1.79e-02
REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION	68	4.16e-04	2.47e-01	1.80e-02
REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS	63	4.69e-04	2.55e-01	1.93e-02
REACTOME RNA POLYMERASE I TRANSCRIPTION	102	4.69e-04	2.00e-01	1.93e-02
REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX	85	4.87e-04	2.19e-01	1.95e-02
REACTOME RESPIRATORY ELECTRON TRANSPORT	90	5.61e-04	2.10e-01	2.19e-02
REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS	60	6.38e-04	2.55e-01	2.39e-02
REACTOME BETA DEFENSINS	27	6.40e-04	3.80e-01	2.39e-02
REACTOME DEVELOPMENTAL BIOLOGY	1115	9.03e-04	5.89e-02	3.30e-02
REACTOME DEFENSINS	33	9.40e-04	3.33e-01	3.36e-02
REACTOME RHO GTPASES ACTIVATE PKNS	86	9.61e-04	2.06e-01	3.36e-02
REACTOME DNA REPLICATION PRE INITIATION	150	1.04e-03	1.55e-01	3.52e-02
REACTOME HDACS DEACETYLATE HISTONES	85	1.05e-03	2.06e-01	3.52e-02
REACTOME PHOSPHOLIPID METABOLISM	201	1.20e-03	-1.32e-01	3.95e-02
REACTOME SCAVENGING BY CLASS A RECEPTORS	19	1.36e-03	4.24e-01	4.35e-02
REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS	113	1.38e-03	1.74e-01	4.35e-02
REACTOME SIGNALING BY GPCR	673	1.57e-03	-7.15e-02	4.86e-02
REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE	52	1.68e-03	2.52e-01	5.10e-02
REACTOME NERVOUS SYSTEM DEVELOPMENT	552	1.87e-03	7.74e-02	5.60e-02
REACTOME TELOMERE MAINTENANCE	106	2.00e-03	1.74e-01	5.87e-02
REACTOME GENE SILENCING BY RNA	133	2.25e-03	1.53e-01	6.47e-02
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY	33	2.46e-03	3.05e-01	6.96e-02
REACTOME DNA REPLICATION	178	2.50e-03	1.31e-01	6.96e-02
REACTOME ESTROGEN DEPENDENT GENE EXPRESSION	140	2.59e-03	1.47e-01	7.08e-02
REACTOME DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING	61	2.96e-03	2.20e-01	7.97e-02
REACTOME ABC TRANSPORTER DISORDERS	76	3.19e-03	1.96e-01	8.44e-02
REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP	104	3.29e-03	1.67e-01	8.58e-02
REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	66	3.40e-03	2.08e-01	8.72e-02
REACTOME ORC1 REMOVAL FROM CHROMATIN	70	3.46e-03	2.02e-01	8.75e-02
REACTOME ANTIMICROBIAL PEPTIDES	76	3.52e-03	1.94e-01	8.75e-02
REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY	72	3.77e-03	1.97e-01	9.16e-02
REACTOME ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY	10	3.79e-03	-5.29e-01	9.16e-02
REACTOME EICOSANOID LIGAND BINDING RECEPTORS	14	4.29e-03	-4.41e-01	1.02e-01
REACTOME CONDENSATION OF PROPHASE CHROMOSOMES	66	4.69e-03	2.01e-01	1.09e-01
REACTOME INTERLEUKIN 18 SIGNALING	8	4.71e-03	-5.77e-01	1.09e-01
REACTOME NEGATIVE REGULATION OF NOTCH4 SIGNALING	53	5.02e-03	2.23e-01	1.14e-01
REACTOME MEIOTIC RECOMBINATION	80	5.05e-03	1.81e-01	1.14e-01
REACTOME G ALPHA I SIGNALLING EVENTS	304	5.31e-03	-9.29e-02	1.18e-01
REACTOME CHROMOSOME MAINTENANCE	130	5.51e-03	1.41e-01	1.21e-01
REACTOME FATTY ACIDS	15	6.10e-03	4.09e-01	1.32e-01
REACTOME EICOSANOIDS	12	6.48e-03	4.54e-01	1.38e-01
REACTOME GPCR LIGAND BINDING	444	6.53e-03	-7.53e-02	1.38e-01
REACTOME UCH PROTEINASES	99	6.74e-03	1.58e-01	1.40e-01
REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	99	6.96e-03	1.57e-01	1.43e-01
REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	54	7.05e-03	2.12e-01	1.43e-01
REACTOME RMTS METHYLATE HISTONE ARGININES	72	7.20e-03	1.83e-01	1.44e-01
REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS	42	7.64e-03	2.38e-01	1.50e-01
REACTOME VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS	42	7.90e-03	-2.37e-01	1.50e-01
REACTOME RNA POLYMERASE II TRANSCRIBES SNRNA GENES	77	7.95e-03	1.75e-01	1.50e-01
REACTOME DEGRADATION OF AXIN	54	7.98e-03	2.09e-01	1.50e-01
REACTOME G ALPHA Q SIGNALLING EVENTS	206	8.02e-03	-1.07e-01	1.50e-01
REACTOME HATS ACETYLATE HISTONES	129	8.06e-03	1.35e-01	1.50e-01
REACTOME REGULATION OF FZD BY UBIQUITINATION	21	8.47e-03	3.32e-01	1.55e-01
REACTOME TRANSPORT OF RCBL WITHIN THE BODY	8	8.52e-03	-5.37e-01	1.55e-01
REACTOME DEGRADATION OF GLI1 BY THE PROTEASOME	59	8.64e-03	1.98e-01	1.56e-01
REACTOME TNFR2 NON CANONICAL NF KB PATHWAY	96	8.89e-03	1.55e-01	1.58e-01
REACTOME SEROTONIN NEUROTRANSMITTER RELEASE CYCLE	17	8.97e-03	3.66e-01	1.58e-01
REACTOME CELLULAR RESPONSE TO HYPOXIA	74	9.13e-03	1.75e-01	1.58e-01
REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	353	9.18e-03	8.07e-02	1.58e-01
REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS	83	9.22e-03	1.65e-01	1.58e-01
REACTOME DEGRADATION OF DVL	56	9.71e-03	2.00e-01	1.62e-01
REACTOME STABILIZATION OF P53	56	9.75e-03	2.00e-01	1.62e-01
REACTOME BASE EXCISION REPAIR AP SITE FORMATION	59	9.80e-03	1.94e-01	1.62e-01
REACTOME SIGNALING BY WNT	318	1.08e-02	8.32e-02	1.77e-01
REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	46	1.10e-02	2.17e-01	1.79e-01
REACTOME CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT	19	1.11e-02	3.36e-01	1.79e-01
REACTOME CREATINE METABOLISM	9	1.13e-02	-4.87e-01	1.81e-01
REACTOME OXIDATIVE STRESS INDUCED SENESCENCE	118	1.15e-02	1.35e-01	1.81e-01
REACTOME HEDGEHOG ON STATE	85	1.16e-02	1.58e-01	1.81e-01
REACTOME INFECTIOUS DISEASE	910	1.17e-02	4.93e-02	1.81e-01
REACTOME G2 M CHECKPOINTS	162	1.19e-02	1.15e-01	1.82e-01
REACTOME HEDGEHOG LIGAND BIOGENESIS	64	1.21e-02	1.81e-01	1.84e-01
REACTOME AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA	54	1.25e-02	1.96e-01	1.89e-01
REACTOME UB SPECIFIC PROCESSING PROTEASES	187	1.28e-02	1.06e-01	1.91e-01
REACTOME PCP CE PATHWAY	91	1.34e-02	1.50e-01	1.98e-01
REACTOME HCMV EARLY EVENTS	128	1.37e-02	1.26e-01	2.00e-01
REACTOME ADHERENS JUNCTIONS INTERACTIONS	33	1.38e-02	2.48e-01	2.00e-01
REACTOME METABOLISM OF LIPIDS	709	1.39e-02	-5.42e-02	2.01e-01
REACTOME ESR MEDIATED SIGNALING	210	1.44e-02	9.80e-02	2.06e-01
REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION	90	1.51e-02	1.48e-01	2.14e-01
REACTOME PARACETAMOL ADME	26	1.54e-02	-2.74e-01	2.16e-01
REACTOME DRUG ADME	103	1.57e-02	-1.38e-01	2.18e-01
REACTOME PHASE II CONJUGATION OF COMPOUNDS	102	1.64e-02	-1.37e-01	2.27e-01
REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT	236	1.67e-02	-9.05e-02	2.28e-01
REACTOME CELLULAR RESPONSES TO STIMULI	779	1.72e-02	5.02e-02	2.34e-01
REACTOME COMPLEX I BIOGENESIS	49	1.83e-02	1.95e-01	2.46e-01
REACTOME FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS	8	1.84e-02	4.81e-01	2.46e-01
REACTOME INTERFERON GAMMA SIGNALING	88	1.89e-02	-1.45e-01	2.50e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR2	29	1.93e-02	2.51e-01	2.54e-01
REACTOME CD22 MEDIATED BCR REGULATION	5	1.99e-02	-6.01e-01	2.57e-01
REACTOME SYNTHESIS OF PC	27	2.01e-02	-2.59e-01	2.57e-01
REACTOME METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS	122	2.03e-02	-1.22e-01	2.57e-01
REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	16	2.04e-02	3.35e-01	2.57e-01
REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21	59	2.05e-02	1.74e-01	2.57e-01
REACTOME NUCLEAR EVENTS MEDIATED BY NFE2L2	77	2.06e-02	1.53e-01	2.57e-01
REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	13	2.07e-02	-3.71e-01	2.57e-01
REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	86	2.13e-02	1.44e-01	2.63e-01
REACTOME ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA	5	2.22e-02	-5.91e-01	2.72e-01
REACTOME RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES	16	2.26e-02	3.29e-01	2.74e-01
REACTOME REGULATION OF RAS BY GAPS	66	2.27e-02	1.62e-01	2.74e-01
REACTOME FOLDING OF ACTIN BY CCT TRIC	10	2.31e-02	4.15e-01	2.76e-01
REACTOME RESPONSE TO METAL IONS	14	2.35e-02	-3.50e-01	2.76e-01
REACTOME METABOLISM OF POLYAMINES	56	2.35e-02	1.75e-01	2.76e-01
REACTOME BICARBONATE TRANSPORTERS	10	2.38e-02	-4.13e-01	2.76e-01
REACTOME PI 3K CASCADE FGFR1	21	2.38e-02	2.85e-01	2.76e-01
REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	21	2.39e-02	2.85e-01	2.76e-01
REACTOME MELANIN BIOSYNTHESIS	5	2.43e-02	5.82e-01	2.79e-01
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	53	2.45e-02	1.79e-01	2.79e-01
REACTOME RNA POLYMERASE II PRE TRANSCRIPTION EVENTS	77	2.59e-02	1.47e-01	2.93e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1	31	2.63e-02	2.31e-01	2.95e-01
REACTOME PI 3K CASCADE FGFR2	22	2.66e-02	2.73e-01	2.97e-01
REACTOME UPTAKE OF DIETARY COBALAMINS INTO ENTEROCYTES	9	2.69e-02	-4.26e-01	2.97e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	28	2.69e-02	2.42e-01	2.97e-01
REACTOME CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS	19	2.72e-02	2.93e-01	2.97e-01
REACTOME FRS MEDIATED FGFR1 SIGNALING	23	2.76e-02	2.65e-01	2.99e-01
REACTOME INTERLEUKIN 7 SIGNALING	31	2.77e-02	2.29e-01	2.99e-01
REACTOME ECM PROTEOGLYCANS	73	2.85e-02	1.48e-01	3.04e-01
REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS	28	2.86e-02	-2.39e-01	3.04e-01
REACTOME COPII MEDIATED VESICLE TRANSPORT	66	2.87e-02	-1.56e-01	3.04e-01
REACTOME CELL CELL JUNCTION ORGANIZATION	64	2.98e-02	1.57e-01	3.13e-01
REACTOME GLUCURONIDATION	23	2.99e-02	-2.61e-01	3.13e-01
REACTOME FRS MEDIATED FGFR2 SIGNALING	24	3.03e-02	2.55e-01	3.14e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS	9	3.07e-02	-4.16e-01	3.17e-01
REACTOME METABOLISM OF CARBOHYDRATES	279	3.09e-02	-7.51e-02	3.17e-01
REACTOME ACYL CHAIN REMODELLING OF PG	18	3.12e-02	-2.93e-01	3.18e-01
REACTOME DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX	83	3.14e-02	1.37e-01	3.18e-01
REACTOME REGULATION OF PTEN STABILITY AND ACTIVITY	67	3.18e-02	1.52e-01	3.20e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3	11	3.26e-02	3.72e-01	3.27e-01
REACTOME TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS	82	3.31e-02	-1.36e-01	3.29e-01
REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY	46	3.34e-02	1.81e-01	3.30e-01
REACTOME GLUTATHIONE CONJUGATION	33	3.40e-02	-2.13e-01	3.33e-01
REACTOME MITOCHONDRIAL TRANSLATION	93	3.41e-02	1.27e-01	3.33e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER	28	3.46e-02	2.31e-01	3.35e-01
REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY	26	3.47e-02	-2.39e-01	3.35e-01
REACTOME INTERLEUKIN 1 SIGNALING	110	3.57e-02	1.16e-01	3.39e-01
REACTOME METAL ION SLC TRANSPORTERS	23	3.58e-02	-2.53e-01	3.39e-01
REACTOME SIGNALING BY NUCLEAR RECEPTORS	283	3.59e-02	7.25e-02	3.39e-01
REACTOME MEIOTIC SYNAPSIS	73	3.60e-02	1.42e-01	3.39e-01
REACTOME SYNTHESIS OF PA	38	3.62e-02	-1.96e-01	3.40e-01
REACTOME HCMV LATE EVENTS	110	3.66e-02	1.15e-01	3.41e-01
REACTOME CDC42 GTPASE CYCLE	144	3.70e-02	-1.01e-01	3.41e-01
REACTOME ASPIRIN ADME	42	3.70e-02	-1.86e-01	3.41e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1	229	3.77e-02	7.97e-02	3.46e-01
REACTOME RETINOID CYCLE DISEASE EVENTS	11	3.83e-02	3.61e-01	3.46e-01
REACTOME REGULATION OF RUNX3 EXPRESSION AND ACTIVITY	54	3.83e-02	1.63e-01	3.46e-01
REACTOME INTEGRATION OF ENERGY METABOLISM	105	3.86e-02	-1.17e-01	3.46e-01
REACTOME LIGAND RECEPTOR INTERACTIONS	8	3.87e-02	4.22e-01	3.46e-01
REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION	74	3.88e-02	-1.39e-01	3.46e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION	41	4.03e-02	1.85e-01	3.57e-01
REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS	8	4.07e-02	-4.18e-01	3.58e-01
REACTOME DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE	76	4.09e-02	1.36e-01	3.58e-01
REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL	58	4.14e-02	1.55e-01	3.58e-01
REACTOME GPER1 SIGNALING	45	4.16e-02	-1.76e-01	3.58e-01
REACTOME SIGNALING BY FGFR2 IN DISEASE	42	4.18e-02	1.81e-01	3.58e-01
REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	17	4.19e-02	2.85e-01	3.58e-01
REACTOME FIBRONECTIN MATRIX FORMATION	6	4.19e-02	-4.80e-01	3.58e-01
REACTOME MEIOSIS	110	4.23e-02	1.12e-01	3.60e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS	8	4.36e-02	-4.12e-01	3.69e-01
REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III	31	4.52e-02	-2.08e-01	3.81e-01
REACTOME CIRCADIAN CLOCK	68	4.56e-02	-1.40e-01	3.81e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES	12	4.57e-02	-3.33e-01	3.81e-01
REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	17	4.64e-02	2.79e-01	3.85e-01
REACTOME SIGNALING BY NOTCH	234	4.69e-02	7.54e-02	3.87e-01
REACTOME HEMOSTASIS	591	4.72e-02	-4.78e-02	3.87e-01
REACTOME DISEASES OF MITOTIC CELL CYCLE	37	4.74e-02	-1.88e-01	3.87e-01
REACTOME MET RECEPTOR ACTIVATION	6	4.81e-02	-4.66e-01	3.91e-01
REACTOME ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA	9	4.97e-02	-3.78e-01	4.02e-01
REACTOME SYNTHESIS OF LIPOXINS LX	6	5.01e-02	-4.62e-01	4.03e-01
REACTOME CONSTITUTIVE SIGNALING BY EGFRVIII	15	5.16e-02	2.90e-01	4.11e-01
REACTOME METALLOTHIONEINS BIND METALS	11	5.16e-02	-3.39e-01	4.11e-01
REACTOME MAPK6 MAPK4 SIGNALING	91	5.24e-02	1.18e-01	4.13e-01
REACTOME ACYL CHAIN REMODELLING OF PC	27	5.24e-02	-2.16e-01	4.13e-01
REACTOME NUCLEAR ENVELOPE NE REASSEMBLY	74	5.25e-02	-1.30e-01	4.13e-01
REACTOME COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC	98	5.31e-02	-1.13e-01	4.13e-01
REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER	77	5.32e-02	1.27e-01	4.13e-01
REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION	23	5.35e-02	2.33e-01	4.13e-01
REACTOME PROSTANOID LIGAND RECEPTORS	9	5.36e-02	-3.72e-01	4.13e-01
REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES	34	5.45e-02	-1.91e-01	4.18e-01
REACTOME GOLGI TO ER RETROGRADE TRANSPORT	132	5.47e-02	-9.68e-02	4.18e-01
REACTOME APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS	87	5.56e-02	1.19e-01	4.22e-01
REACTOME ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS	17	5.58e-02	-2.68e-01	4.22e-01
REACTOME ER TO GOLGI ANTEROGRADE TRANSPORT	152	5.61e-02	-8.98e-02	4.22e-01
REACTOME ZINC TRANSPORTERS	15	5.67e-02	-2.84e-01	4.25e-01
REACTOME RHOV GTPASE CYCLE	36	5.70e-02	-1.83e-01	4.26e-01
REACTOME SIGNALING BY NTRK2 TRKB	25	5.78e-02	2.19e-01	4.30e-01
REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	24	5.88e-02	2.23e-01	4.35e-01
REACTOME CHYLOMICRON ASSEMBLY	10	5.92e-02	3.44e-01	4.36e-01
REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS	6	6.15e-02	4.41e-01	4.45e-01
REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION	42	6.19e-02	-1.66e-01	4.45e-01
REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	98	6.20e-02	1.09e-01	4.45e-01
REACTOME G1 S DNA DAMAGE CHECKPOINTS	67	6.23e-02	1.32e-01	4.45e-01
REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	9	6.25e-02	-3.59e-01	4.45e-01
REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	183	6.26e-02	-7.98e-02	4.45e-01
REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE	11	6.26e-02	-3.24e-01	4.45e-01
REACTOME SENSORY PERCEPTION OF TASTE	47	6.27e-02	-1.57e-01	4.45e-01
REACTOME METALLOPROTEASE DUBS	36	6.29e-02	1.79e-01	4.45e-01
REACTOME INOSITOL PHOSPHATE METABOLISM	45	6.38e-02	-1.60e-01	4.48e-01
REACTOME HIV TRANSCRIPTION INITIATION	43	6.39e-02	1.63e-01	4.48e-01
REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	32	6.43e-02	-1.89e-01	4.49e-01
REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF	17	6.46e-02	-2.59e-01	4.49e-01
REACTOME LTC4 CYSLTR MEDIATED IL4 PRODUCTION	6	6.64e-02	-4.33e-01	4.58e-01
REACTOME IRS MEDIATED SIGNALLING	47	6.64e-02	1.55e-01	4.58e-01
REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	11	6.74e-02	-3.18e-01	4.60e-01
REACTOME ACYL CHAIN REMODELLING OF PE	29	6.75e-02	-1.96e-01	4.60e-01
REACTOME THE PHOTOTRANSDUCTION CASCADE	32	6.75e-02	-1.87e-01	4.60e-01
REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS	312	6.81e-02	-6.01e-02	4.61e-01
REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	16	6.85e-02	-2.63e-01	4.61e-01
REACTOME COHESIN LOADING ONTO CHROMATIN	8	6.86e-02	-3.72e-01	4.61e-01
REACTOME RHOU GTPASE CYCLE	37	6.94e-02	-1.72e-01	4.65e-01
REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	28	7.04e-02	1.98e-01	4.70e-01
REACTOME SIGNALING BY NODAL	20	7.14e-02	-2.33e-01	4.73e-01
REACTOME RECEPTOR MEDIATED MITOPHAGY	10	7.14e-02	-3.29e-01	4.73e-01
REACTOME DISEASES OF BASE EXCISION REPAIR	5	7.17e-02	-4.65e-01	4.73e-01
REACTOME TRANSCRIPTION OF THE HIV GENOME	66	7.20e-02	1.28e-01	4.73e-01
REACTOME ASPARAGINE N LINKED GLYCOSYLATION	299	7.32e-02	-6.02e-02	4.77e-01
REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING	12	7.35e-02	-2.98e-01	4.77e-01
REACTOME TRANSPORT OF SMALL MOLECULES	697	7.37e-02	-3.98e-02	4.77e-01
REACTOME MITOCHONDRIAL PROTEIN IMPORT	58	7.39e-02	1.36e-01	4.77e-01
REACTOME SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE	91	7.41e-02	1.08e-01	4.77e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST	14	7.46e-02	-2.75e-01	4.78e-01
REACTOME HUR ELAVL1 BINDS AND STABILIZES MRNA	8	7.52e-02	-3.63e-01	4.80e-01
REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	101	7.55e-02	-1.02e-01	4.80e-01
REACTOME SIGNALING BY NOTCH4	80	7.57e-02	1.15e-01	4.80e-01
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	263	7.65e-02	6.35e-02	4.83e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS	9	7.79e-02	-3.39e-01	4.90e-01
REACTOME REGULATION OF SIGNALING BY NODAL	9	7.86e-02	-3.39e-01	4.90e-01
REACTOME E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS	58	7.90e-02	1.33e-01	4.90e-01
REACTOME NETRIN MEDIATED REPULSION SIGNALS	8	7.90e-02	3.59e-01	4.90e-01
REACTOME DAG AND IP3 SIGNALING	40	7.92e-02	-1.60e-01	4.90e-01
REACTOME DEFECTIVE CSF2RB CAUSES SMDP5	7	7.94e-02	3.83e-01	4.90e-01
REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	39	8.19e-02	-1.61e-01	5.03e-01
REACTOME ADAPTIVE IMMUNE SYSTEM	729	8.33e-02	-3.77e-02	5.10e-01
REACTOME SIGNALING BY FGFR1	49	8.36e-02	1.43e-01	5.10e-01
REACTOME ACYL CHAIN REMODELLING OF PS	22	8.39e-02	-2.13e-01	5.11e-01
REACTOME SUMOYLATION OF DNA REPLICATION PROTEINS	46	8.53e-02	-1.47e-01	5.17e-01
REACTOME TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE	10	8.64e-02	-3.13e-01	5.22e-01
REACTOME TRIF MEDIATED PROGRAMMED CELL DEATH	9	8.69e-02	-3.29e-01	5.22e-01
REACTOME INSULIN RECEPTOR RECYCLING	29	8.71e-02	-1.84e-01	5.22e-01
REACTOME THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT	77	8.82e-02	1.12e-01	5.24e-01
REACTOME SIGNALING BY EGFR IN CANCER	25	8.83e-02	1.97e-01	5.24e-01
REACTOME G2 M DNA DAMAGE CHECKPOINT	90	8.84e-02	1.04e-01	5.24e-01
REACTOME HEDGEHOG OFF STATE	111	8.92e-02	9.34e-02	5.27e-01
REACTOME TRANSCRIPTIONAL REGULATION BY E2F6	32	8.98e-02	-1.73e-01	5.28e-01
REACTOME TRANSCRIPTIONAL REGULATION BY VENTX	41	9.01e-02	-1.53e-01	5.28e-01
REACTOME PHASE 0 RAPID DEPOLARISATION	31	9.07e-02	1.76e-01	5.30e-01
REACTOME MITOTIC TELOPHASE CYTOKINESIS	11	9.14e-02	-2.94e-01	5.32e-01
REACTOME COSTIMULATION BY THE CD28 FAMILY	64	9.17e-02	-1.22e-01	5.32e-01
REACTOME INTERFERON SIGNALING	193	9.21e-02	-7.03e-02	5.32e-01
REACTOME DEFECTIVE EXT2 CAUSES EXOSTOSES 2	12	9.26e-02	2.80e-01	5.33e-01
REACTOME BASE EXCISION REPAIR	87	9.42e-02	1.04e-01	5.41e-01
REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	79	9.49e-02	1.09e-01	5.43e-01
REACTOME STRIATED MUSCLE CONTRACTION	35	9.54e-02	-1.63e-01	5.44e-01
REACTOME LEISHMANIA INFECTION	156	9.63e-02	-7.71e-02	5.46e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES	43	9.69e-02	-1.46e-01	5.46e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH PI3K	7	9.71e-02	3.62e-01	5.46e-01
REACTOME RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK	47	9.71e-02	1.40e-01	5.46e-01
REACTOME RNA POLYMERASE III CHAIN ELONGATION	18	9.84e-02	2.25e-01	5.50e-01
REACTOME RAC2 GTPASE CYCLE	81	9.85e-02	-1.06e-01	5.50e-01
REACTOME METHYLATION	14	1.02e-01	2.53e-01	5.67e-01
REACTOME NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10	12	1.03e-01	-2.72e-01	5.68e-01
REACTOME P2Y RECEPTORS	9	1.03e-01	-3.14e-01	5.68e-01
REACTOME METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES	33	1.03e-01	-1.64e-01	5.68e-01
REACTOME MATURATION OF SARS COV 2 NUCLEOPROTEIN	15	1.03e-01	-2.43e-01	5.68e-01
REACTOME SIGNALING BY PDGFR IN DISEASE	20	1.04e-01	2.10e-01	5.69e-01
REACTOME ADRENOCEPTORS	9	1.04e-01	3.13e-01	5.69e-01
REACTOME FORMATION OF THE CORNIFIED ENVELOPE	125	1.05e-01	8.40e-02	5.69e-01
REACTOME GRB7 EVENTS IN ERBB2 SIGNALING	5	1.06e-01	-4.18e-01	5.71e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES	49	1.06e-01	-1.33e-01	5.71e-01
REACTOME RHOQ GTPASE CYCLE	57	1.06e-01	-1.24e-01	5.71e-01
REACTOME REGULATION OF INSULIN SECRETION	77	1.07e-01	-1.06e-01	5.73e-01
REACTOME UBIQUINOL BIOSYNTHESIS	8	1.08e-01	-3.28e-01	5.74e-01
REACTOME TP53 REGULATES METABOLIC GENES	81	1.09e-01	1.03e-01	5.74e-01
REACTOME COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM	21	1.09e-01	-2.02e-01	5.74e-01
REACTOME G PROTEIN BETA GAMMA SIGNALLING	30	1.09e-01	-1.69e-01	5.74e-01
REACTOME GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION	42	1.09e-01	-1.43e-01	5.74e-01
REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX	13	1.09e-01	2.57e-01	5.74e-01
REACTOME TCR SIGNALING	113	1.09e-01	8.72e-02	5.74e-01
REACTOME RAC3 GTPASE CYCLE	85	1.10e-01	-1.00e-01	5.76e-01
REACTOME OPIOID SIGNALLING	89	1.12e-01	-9.75e-02	5.80e-01
REACTOME INTEGRIN SIGNALING	27	1.12e-01	-1.77e-01	5.80e-01
REACTOME FCERI MEDIATED NF KB ACTIVATION	78	1.12e-01	1.04e-01	5.80e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX2	117	1.13e-01	8.49e-02	5.80e-01
REACTOME HCMV INFECTION	152	1.13e-01	7.45e-02	5.80e-01
REACTOME GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION	7	1.14e-01	3.45e-01	5.85e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS	7	1.14e-01	-3.45e-01	5.85e-01
REACTOME SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL	8	1.15e-01	-3.22e-01	5.85e-01
REACTOME PLATELET AGGREGATION PLUG FORMATION	39	1.15e-01	-1.46e-01	5.85e-01
REACTOME PREVENTION OF PHAGOSOMAL LYSOSOMAL FUSION	9	1.16e-01	3.03e-01	5.85e-01
REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	14	1.17e-01	-2.42e-01	5.85e-01
REACTOME MRNA SPLICING	197	1.17e-01	6.48e-02	5.85e-01
REACTOME CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY	84	1.17e-01	9.89e-02	5.85e-01
REACTOME KEAP1 NFE2L2 PATHWAY	104	1.18e-01	8.88e-02	5.85e-01
REACTOME PEPTIDE HORMONE BIOSYNTHESIS	13	1.18e-01	-2.51e-01	5.85e-01
REACTOME VITAMIN B1 THIAMIN METABOLISM	5	1.18e-01	-4.04e-01	5.85e-01
REACTOME HEME SIGNALING	47	1.18e-01	-1.32e-01	5.85e-01
REACTOME O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS	38	1.19e-01	1.46e-01	5.85e-01
REACTOME PRE NOTCH EXPRESSION AND PROCESSING	112	1.19e-01	8.52e-02	5.85e-01
REACTOME SIGNALING BY VEGF	102	1.19e-01	-8.93e-02	5.85e-01
REACTOME MHC CLASS II ANTIGEN PRESENTATION	121	1.19e-01	-8.20e-02	5.85e-01
REACTOME RHOBTB1 GTPASE CYCLE	22	1.21e-01	1.91e-01	5.88e-01
REACTOME SARS COV 2 HOST INTERACTIONS	191	1.21e-01	6.50e-02	5.88e-01
REACTOME FANCONI ANEMIA PATHWAY	35	1.22e-01	-1.51e-01	5.88e-01
REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION	26	1.22e-01	-1.75e-01	5.88e-01
REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R	52	1.22e-01	1.24e-01	5.88e-01
REACTOME RAC1 GTPASE CYCLE	172	1.22e-01	-6.83e-02	5.88e-01
REACTOME BINDING OF TCF LEF CTNNB1 TO TARGET GENE PROMOTERS	8	1.23e-01	3.15e-01	5.88e-01
REACTOME INACTIVATION OF CDC42 AND RAC1	8	1.23e-01	3.15e-01	5.88e-01
REACTOME ESTABLISHMENT OF SISTER CHROMATID COHESION	9	1.23e-01	-2.97e-01	5.88e-01
REACTOME RESOLUTION OF ABASIC SITES AP SITES	38	1.24e-01	-1.44e-01	5.89e-01
REACTOME SIGNALING BY MET	78	1.25e-01	1.01e-01	5.89e-01
REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS	21	1.25e-01	-1.93e-01	5.89e-01
REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	19	1.25e-01	-2.03e-01	5.89e-01
REACTOME BIOLOGICAL OXIDATIONS	210	1.26e-01	-6.13e-02	5.90e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR4	26	1.26e-01	1.73e-01	5.90e-01
REACTOME IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS	17	1.26e-01	-2.14e-01	5.91e-01
REACTOME GAP JUNCTION ASSEMBLY	36	1.28e-01	-1.47e-01	5.95e-01
REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	15	1.28e-01	-2.27e-01	5.95e-01
REACTOME HOST INTERACTIONS OF HIV FACTORS	127	1.29e-01	7.79e-02	5.97e-01
REACTOME CRISTAE FORMATION	27	1.30e-01	1.68e-01	5.97e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR3	24	1.30e-01	1.78e-01	5.97e-01
REACTOME INTERLEUKIN 36 PATHWAY	7	1.31e-01	-3.30e-01	5.97e-01
REACTOME CELL CYCLE CHECKPOINTS	284	1.31e-01	5.20e-02	5.97e-01
REACTOME TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX	14	1.31e-01	-2.33e-01	5.97e-01
REACTOME CELLULAR SENESCENCE	189	1.31e-01	6.36e-02	5.97e-01
REACTOME SARS COV 1 HOST INTERACTIONS	92	1.31e-01	9.10e-02	5.97e-01
REACTOME TRANSPORT AND SYNTHESIS OF PAPS	6	1.32e-01	-3.55e-01	5.97e-01
REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	32	1.32e-01	-1.54e-01	5.98e-01
REACTOME ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS	7	1.33e-01	-3.28e-01	5.98e-01
REACTOME PROTEIN UBIQUITINATION	76	1.33e-01	9.96e-02	5.98e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	25	1.33e-01	-1.73e-01	5.98e-01
REACTOME INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL	14	1.35e-01	2.31e-01	6.06e-01
REACTOME REGULATION OF GENE EXPRESSION IN ENDOCRINE COMMITTED NEUROG3 PROGENITOR CELLS	5	1.36e-01	3.85e-01	6.09e-01
REACTOME ACYL CHAIN REMODELLING OF PI	17	1.38e-01	-2.08e-01	6.13e-01
REACTOME MEMBRANE TRAFFICKING	603	1.38e-01	-3.53e-02	6.13e-01
REACTOME DEPOLYMERISATION OF THE NUCLEAR LAMINA	14	1.38e-01	-2.29e-01	6.13e-01
REACTOME MUCOPOLYSACCHARIDOSES	10	1.40e-01	-2.70e-01	6.18e-01
REACTOME CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER	25	1.41e-01	-1.70e-01	6.18e-01
REACTOME SIGNALING BY ERBB2 ECD MUTANTS	16	1.41e-01	2.13e-01	6.18e-01
REACTOME ARYL HYDROCARBON RECEPTOR SIGNALLING	6	1.42e-01	3.47e-01	6.20e-01
REACTOME SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS	12	1.42e-01	2.45e-01	6.20e-01
REACTOME PROCESSING OF SMDT1	16	1.44e-01	2.11e-01	6.25e-01
REACTOME SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS	74	1.45e-01	-9.81e-02	6.28e-01
REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	17	1.46e-01	-2.04e-01	6.33e-01
REACTOME REPRODUCTION	136	1.47e-01	7.20e-02	6.35e-01
REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION	11	1.47e-01	2.52e-01	6.35e-01
REACTOME SIGNALING BY HEDGEHOG	148	1.49e-01	6.88e-02	6.36e-01
REACTOME GDP FUCOSE BIOSYNTHESIS	6	1.49e-01	-3.40e-01	6.36e-01
REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	93	1.49e-01	-8.65e-02	6.36e-01
REACTOME MAPK1 ERK2 ACTIVATION	9	1.50e-01	-2.77e-01	6.36e-01
REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	15	1.51e-01	2.14e-01	6.36e-01
REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING	6	1.51e-01	-3.39e-01	6.36e-01
REACTOME HDMS DEMETHYLATE HISTONES	40	1.51e-01	1.31e-01	6.36e-01
REACTOME FGFRL1 MODULATION OF FGFR1 SIGNALING	13	1.51e-01	2.30e-01	6.36e-01
REACTOME SENSORY PERCEPTION OF SALTY TASTE	6	1.51e-01	-3.38e-01	6.36e-01
REACTOME PYROPTOSIS	27	1.51e-01	-1.60e-01	6.36e-01
REACTOME HIV INFECTION	223	1.53e-01	5.56e-02	6.39e-01
REACTOME SHC MEDIATED CASCADE FGFR1	21	1.54e-01	1.80e-01	6.43e-01
REACTOME MODULATION BY MTB OF HOST IMMUNE SYSTEM	6	1.55e-01	3.35e-01	6.46e-01
REACTOME BUDDING AND MATURATION OF HIV VIRION	28	1.55e-01	-1.55e-01	6.46e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2	17	1.56e-01	1.99e-01	6.47e-01
REACTOME BETA CATENIN INDEPENDENT WNT SIGNALING	145	1.57e-01	6.82e-02	6.47e-01
REACTOME PKA ACTIVATION IN GLUCAGON SIGNALLING	17	1.57e-01	-1.98e-01	6.47e-01
REACTOME TOXICITY OF BOTULINUM TOXIN TYPE D BOTD	5	1.59e-01	3.64e-01	6.53e-01
REACTOME TRNA MODIFICATION IN THE MITOCHONDRION	8	1.59e-01	2.88e-01	6.53e-01
REACTOME CELL JUNCTION ORGANIZATION	89	1.61e-01	8.61e-02	6.57e-01
REACTOME PROTEIN LOCALIZATION	153	1.61e-01	6.56e-02	6.58e-01
REACTOME ORGANIC ANION TRANSPORTERS	10	1.62e-01	-2.55e-01	6.61e-01
REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION	32	1.63e-01	1.42e-01	6.61e-01
REACTOME METABOLISM OF VITAMINS AND COFACTORS	185	1.64e-01	-5.94e-02	6.61e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION TERMINATION	23	1.64e-01	1.68e-01	6.61e-01
REACTOME NEUTROPHIL DEGRANULATION	460	1.64e-01	-3.78e-02	6.61e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION	89	1.65e-01	8.52e-02	6.61e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE	20	1.65e-01	-1.79e-01	6.61e-01
REACTOME CREB3 FACTORS ACTIVATE GENES	8	1.65e-01	-2.83e-01	6.61e-01
REACTOME SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL	25	1.66e-01	-1.60e-01	6.61e-01
REACTOME TELOMERE EXTENSION BY TELOMERASE	22	1.66e-01	1.71e-01	6.61e-01
REACTOME RHO GTPASES ACTIVATE CIT	19	1.67e-01	-1.83e-01	6.61e-01
REACTOME DAP12 SIGNALING	27	1.67e-01	1.54e-01	6.61e-01
REACTOME CHOLINE CATABOLISM	6	1.67e-01	-3.26e-01	6.61e-01
REACTOME NETRIN 1 SIGNALING	49	1.68e-01	1.14e-01	6.63e-01
REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	24	1.69e-01	-1.62e-01	6.64e-01
REACTOME SEROTONIN RECEPTORS	11	1.69e-01	-2.39e-01	6.66e-01
REACTOME RHO GTPASE EFFECTORS	305	1.71e-01	4.56e-02	6.69e-01
REACTOME NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY	6	1.71e-01	-3.23e-01	6.69e-01
REACTOME DISEASES OF IMMUNE SYSTEM	29	1.73e-01	-1.46e-01	6.73e-01
REACTOME APEX1 INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	7	1.73e-01	-2.97e-01	6.74e-01
REACTOME METABOLISM OF FOLATE AND PTERINES	17	1.75e-01	-1.90e-01	6.79e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE GIP	12	1.76e-01	2.25e-01	6.82e-01
REACTOME CATION COUPLED CHLORIDE COTRANSPORTERS	7	1.76e-01	-2.95e-01	6.82e-01
REACTOME THYROXINE BIOSYNTHESIS	10	1.77e-01	-2.46e-01	6.84e-01
REACTOME KERATAN SULFATE KERATIN METABOLISM	34	1.78e-01	-1.33e-01	6.84e-01
REACTOME PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS	21	1.78e-01	-1.70e-01	6.84e-01
REACTOME INSULIN RECEPTOR SIGNALLING CASCADE	53	1.79e-01	1.07e-01	6.84e-01
REACTOME G ALPHA S SIGNALLING EVENTS	155	1.79e-01	-6.25e-02	6.84e-01
REACTOME TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX	10	1.80e-01	2.45e-01	6.84e-01
REACTOME PHENYLALANINE AND TYROSINE METABOLISM	11	1.80e-01	-2.34e-01	6.84e-01
REACTOME MATURATION OF PROTEIN 3A	9	1.81e-01	-2.58e-01	6.85e-01
REACTOME TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA	17	1.81e-01	1.87e-01	6.85e-01
REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS	8	1.83e-01	2.72e-01	6.88e-01
REACTOME DARPP 32 EVENTS	24	1.83e-01	-1.57e-01	6.88e-01
REACTOME G PROTEIN MEDIATED EVENTS	53	1.84e-01	-1.06e-01	6.88e-01
REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	15	1.84e-01	-1.98e-01	6.88e-01
REACTOME NEUROTRANSMITTER RELEASE CYCLE	48	1.84e-01	1.11e-01	6.88e-01
REACTOME SMOOTH MUSCLE CONTRACTION	43	1.84e-01	-1.17e-01	6.88e-01
REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	11	1.85e-01	-2.31e-01	6.88e-01
REACTOME SYNTHESIS OF PE	13	1.86e-01	-2.12e-01	6.89e-01
REACTOME TAK1 DEPENDENT IKK AND NF KAPPA B ACTIVATION	41	1.86e-01	1.19e-01	6.89e-01
REACTOME PROTON COUPLED MONOCARBOXYLATE TRANSPORT	6	1.87e-01	-3.11e-01	6.89e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX3	94	1.87e-01	7.88e-02	6.89e-01
REACTOME RORA ACTIVATES GENE EXPRESSION	17	1.88e-01	-1.84e-01	6.91e-01
REACTOME SYNTHESIS OF PG	8	1.89e-01	-2.68e-01	6.91e-01
REACTOME KSRP KHSRP BINDS AND DESTABILIZES MRNA	17	1.89e-01	1.84e-01	6.91e-01
REACTOME CHROMATIN MODIFYING ENZYMES	252	1.89e-01	4.80e-02	6.91e-01
REACTOME LRR FLII INTERACTING PROTEIN 1 LRRFIP1 ACTIVATES TYPE I IFN PRODUCTION	5	1.90e-01	-3.39e-01	6.91e-01
REACTOME FGFR1B LIGAND BINDING AND ACTIVATION	6	1.90e-01	3.09e-01	6.91e-01
REACTOME CD28 CO STIMULATION	32	1.90e-01	-1.34e-01	6.91e-01
REACTOME COMMON PATHWAY OF FIBRIN CLOT FORMATION	21	1.91e-01	-1.65e-01	6.91e-01
REACTOME REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM	11	1.92e-01	-2.27e-01	6.94e-01
REACTOME SERINE BIOSYNTHESIS	9	1.93e-01	2.50e-01	6.96e-01
REACTOME INTERLEUKIN 1 PROCESSING	9	1.94e-01	2.50e-01	6.96e-01
REACTOME CA DEPENDENT EVENTS	36	1.94e-01	-1.25e-01	6.96e-01
REACTOME DEUBIQUITINATION	260	1.95e-01	4.67e-02	6.96e-01
REACTOME ION CHANNEL TRANSPORT	172	1.95e-01	-5.73e-02	6.96e-01
REACTOME LATE ENDOSOMAL MICROAUTOPHAGY	33	1.96e-01	-1.30e-01	6.97e-01
REACTOME SEMAPHORIN INTERACTIONS	61	1.96e-01	-9.57e-02	6.97e-01
REACTOME GAP JUNCTION TRAFFICKING AND REGULATION	49	1.97e-01	-1.07e-01	6.97e-01
REACTOME MTORC1 MEDIATED SIGNALLING	23	1.97e-01	1.55e-01	6.97e-01
REACTOME EPHA MEDIATED GROWTH CONE COLLAPSE	29	1.97e-01	-1.38e-01	6.97e-01
REACTOME PI 3K CASCADE FGFR4	19	1.98e-01	1.71e-01	6.97e-01
REACTOME PINK1 PRKN MEDIATED MITOPHAGY	22	1.98e-01	1.58e-01	6.97e-01
REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	73	1.98e-01	8.71e-02	6.97e-01
REACTOME NS1 MEDIATED EFFECTS ON HOST PATHWAYS	41	1.99e-01	-1.16e-01	6.98e-01
REACTOME METABOLISM OF FAT SOLUBLE VITAMINS	46	2.00e-01	1.09e-01	6.98e-01
REACTOME PHENYLALANINE METABOLISM	6	2.00e-01	-3.02e-01	6.98e-01
REACTOME GLYCOLYSIS	70	2.00e-01	-8.85e-02	6.98e-01
REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION	10	2.01e-01	2.33e-01	7.00e-01
REACTOME ETHANOL OXIDATION	12	2.02e-01	2.13e-01	7.00e-01
REACTOME NEUROTOXICITY OF CLOSTRIDIUM TOXINS	10	2.02e-01	2.33e-01	7.00e-01
REACTOMEMATURATION OF SARS COV 1 NUCLEOPROTEIN	11	2.03e-01	-2.22e-01	7.00e-01
REACTOME FRS MEDIATED FGFR4 SIGNALING	21	2.03e-01	1.60e-01	7.02e-01
REACTOME RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS	9	2.04e-01	-2.44e-01	7.03e-01
REACTOME SIGNALING BY INTERLEUKINS	444	2.05e-01	3.51e-02	7.03e-01
REACTOME PI 3K CASCADE FGFR3	17	2.05e-01	1.77e-01	7.04e-01
REACTOME CALNEXIN CALRETICULIN CYCLE	26	2.06e-01	1.43e-01	7.04e-01
REACTOME SIGNALING BY ERYTHROPOIETIN	25	2.07e-01	1.46e-01	7.04e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS	15	2.07e-01	-1.88e-01	7.04e-01
REACTOME SIGNAL TRANSDUCTION BY L1	20	2.07e-01	-1.63e-01	7.04e-01
REACTOME ARACHIDONATE PRODUCTION FROM DAG	5	2.08e-01	-3.25e-01	7.04e-01
REACTOME ACYL CHAIN REMODELING OF CL	5	2.08e-01	3.25e-01	7.04e-01
REACTOME MISCELLANEOUS SUBSTRATES	12	2.08e-01	2.10e-01	7.04e-01
REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	20	2.09e-01	-1.62e-01	7.05e-01
REACTOME AZATHIOPRINE ADME	22	2.10e-01	-1.55e-01	7.05e-01
REACTOME CARGO CONCENTRATION IN THE ER	32	2.10e-01	-1.28e-01	7.05e-01
REACTOME SEMA4D IN SEMAPHORIN SIGNALING	24	2.11e-01	-1.48e-01	7.06e-01
REACTOME SYNTHESIS OF PI	5	2.12e-01	-3.23e-01	7.06e-01
REACTOME FC EPSILON RECEPTOR FCERI SIGNALING	127	2.12e-01	6.42e-02	7.06e-01
REACTOME FRS MEDIATED FGFR3 SIGNALING	19	2.13e-01	1.65e-01	7.07e-01
REACTOME GLUCAGON TYPE LIGAND RECEPTORS	32	2.13e-01	-1.27e-01	7.07e-01
REACTOME RAS PROCESSING	22	2.14e-01	1.53e-01	7.10e-01
REACTOME RIPK1 MEDIATED REGULATED NECROSIS	30	2.15e-01	1.31e-01	7.11e-01
REACTOME FCGR3A MEDIATED IL10 SYNTHESIS	36	2.15e-01	-1.19e-01	7.11e-01
REACTOME LYSOSPHINGOLIPID AND LPA RECEPTORS	14	2.16e-01	-1.91e-01	7.13e-01
REACTOME MUSCLE CONTRACTION	197	2.17e-01	-5.10e-02	7.14e-01
REACTOME REGULATION OF NF KAPPA B SIGNALING	17	2.19e-01	1.72e-01	7.17e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN	13	2.19e-01	-1.97e-01	7.17e-01
REACTOME MITOTIC PROPHASE	134	2.19e-01	6.15e-02	7.17e-01
REACTOME NEF AND SIGNAL TRANSDUCTION	8	2.21e-01	-2.50e-01	7.22e-01
REACTOME SYNAPTIC ADHESION LIKE MOLECULES	19	2.24e-01	-1.61e-01	7.30e-01
REACTOME RHO GTPASES ACTIVATE ROCKS	19	2.25e-01	-1.61e-01	7.30e-01
REACTOME POTENTIAL THERAPEUTICS FOR SARS	92	2.25e-01	-7.32e-02	7.30e-01
REACTOME SIGNALING BY RNF43 MUTANTS	8	2.26e-01	2.47e-01	7.30e-01
REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS	81	2.26e-01	-7.78e-02	7.30e-01
REACTOME EPH EPHRIN MEDIATED REPULSION OF CELLS	50	2.26e-01	-9.89e-02	7.30e-01
REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	15	2.27e-01	-1.80e-01	7.30e-01
REACTOME METABOLISM OF INGESTED SEMET SEC MESEC INTO H2SE	7	2.27e-01	-2.64e-01	7.30e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM	38	2.29e-01	1.13e-01	7.31e-01
REACTOME REGULATION OF BACH1 ACTIVITY	11	2.29e-01	2.10e-01	7.31e-01
REACTOME LIPID PARTICLE ORGANIZATION	6	2.30e-01	-2.83e-01	7.31e-01
REACTOME TRAF6 MEDIATED NF KB ACTIVATION	24	2.31e-01	1.41e-01	7.31e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS	7	2.31e-01	2.61e-01	7.31e-01
REACTOME SIGNALING BY NTRKS	132	2.31e-01	6.03e-02	7.31e-01
REACTOME KERATAN SULFATE BIOSYNTHESIS	28	2.32e-01	-1.31e-01	7.31e-01
REACTOME SODIUM COUPLED PHOSPHATE COTRANSPORTERS	5	2.32e-01	-3.09e-01	7.31e-01
REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING	32	2.33e-01	1.22e-01	7.31e-01
REACTOME NUCLEAR ENVELOPE BREAKDOWN	52	2.33e-01	-9.57e-02	7.31e-01
REACTOME PI3K EVENTS IN ERBB4 SIGNALING	10	2.33e-01	2.18e-01	7.31e-01
REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	20	2.34e-01	-1.54e-01	7.31e-01
REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS	63	2.35e-01	-8.66e-02	7.31e-01
REACTOME PERK REGULATES GENE EXPRESSION	31	2.35e-01	1.23e-01	7.31e-01
REACTOME CELL CELL COMMUNICATION	126	2.35e-01	6.12e-02	7.31e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS	14	2.36e-01	-1.83e-01	7.31e-01
REACTOME HS GAG BIOSYNTHESIS	28	2.36e-01	1.29e-01	7.31e-01
REACTOME ACTIVATION OF BH3 ONLY PROTEINS	30	2.36e-01	-1.25e-01	7.31e-01
REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING	33	2.36e-01	1.19e-01	7.31e-01
REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	23	2.36e-01	-1.43e-01	7.31e-01
REACTOME RHO GTPASES ACTIVATE IQGAPS	31	2.37e-01	-1.23e-01	7.31e-01
REACTOME ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS	20	2.37e-01	-1.53e-01	7.31e-01
REACTOME INTERLEUKIN 35 SIGNALLING	12	2.38e-01	-1.97e-01	7.32e-01
REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	30	2.39e-01	1.24e-01	7.32e-01
REACTOME PLATELET CALCIUM HOMEOSTASIS	27	2.39e-01	-1.31e-01	7.32e-01
REACTOME DNA DOUBLE STRAND BREAK RESPONSE	74	2.40e-01	7.91e-02	7.32e-01
REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	57	2.41e-01	8.99e-02	7.34e-01
REACTOME SULFIDE OXIDATION TO SULFATE	6	2.42e-01	-2.76e-01	7.38e-01
REACTOME CLEC7A DECTIN 1 SIGNALING	97	2.43e-01	6.86e-02	7.40e-01
REACTOME ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS	27	2.44e-01	1.29e-01	7.42e-01
REACTOME N GLYCAN TRIMMING AND ELONGATION IN THE CIS GOLGI	5	2.46e-01	2.99e-01	7.45e-01
REACTOME COBALAMIN CBL METABOLISM	7	2.47e-01	2.53e-01	7.45e-01
REACTOME SLC TRANSPORTER DISORDERS	94	2.47e-01	-6.90e-02	7.45e-01
REACTOME ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION	28	2.47e-01	-1.26e-01	7.45e-01
REACTOME MAPK FAMILY SIGNALING CASCADES	314	2.48e-01	3.79e-02	7.46e-01
REACTOME APOPTOTIC EXECUTION PHASE	49	2.49e-01	-9.53e-02	7.46e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION TERMINATION	30	2.49e-01	1.22e-01	7.46e-01
REACTOME CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND	9	2.50e-01	2.22e-01	7.46e-01
REACTOME BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA	17	2.50e-01	1.61e-01	7.46e-01
REACTOME MET ACTIVATES PTK2 SIGNALING	30	2.51e-01	1.21e-01	7.48e-01
REACTOME DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE	17	2.52e-01	1.61e-01	7.48e-01
REACTOME DEFECTIVE LFNG CAUSES SCDO3	5	2.53e-01	-2.95e-01	7.50e-01
REACTOME VLDL CLEARANCE	6	2.53e-01	2.69e-01	7.50e-01
REACTOME INTERLEUKIN 27 SIGNALING	11	2.56e-01	-1.98e-01	7.57e-01
REACTOME SYNTHESIS OF DNA	119	2.56e-01	6.02e-02	7.57e-01
REACTOME TRP CHANNELS	27	2.57e-01	1.26e-01	7.57e-01
REACTOME FOXO MEDIATED TRANSCRIPTION	65	2.58e-01	8.12e-02	7.58e-01
REACTOME CLATHRIN MEDIATED ENDOCYTOSIS	139	2.60e-01	5.54e-02	7.63e-01
REACTOME RECYCLING OF EIF2 GDP	7	2.61e-01	2.46e-01	7.64e-01
REACTOME SODIUM PROTON EXCHANGERS	7	2.61e-01	-2.45e-01	7.64e-01
REACTOME SIGNALING BY FGFR4 IN DISEASE	11	2.62e-01	1.95e-01	7.65e-01
REACTOME FLT3 SIGNALING BY CBL MUTANTS	7	2.64e-01	2.44e-01	7.68e-01
REACTOME FREE FATTY ACID RECEPTORS	5	2.64e-01	-2.88e-01	7.68e-01
REACTOME SYNTHESIS OF DIPHTHAMIDE EEF2	8	2.65e-01	2.28e-01	7.68e-01
REACTOME COPI MEDIATED ANTEROGRADE TRANSPORT	101	2.65e-01	-6.42e-02	7.68e-01
REACTOME DISORDERS OF TRANSMEMBRANE TRANSPORTERS	170	2.65e-01	4.95e-02	7.68e-01
REACTOME REGULATION OF IFNA IFNB SIGNALING	23	2.68e-01	1.33e-01	7.74e-01
REACTOME CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS	100	2.69e-01	6.40e-02	7.76e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K	12	2.69e-01	1.84e-01	7.76e-01
REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	22	2.70e-01	-1.36e-01	7.77e-01
REACTOME G ALPHA Z SIGNALLING EVENTS	48	2.71e-01	-9.18e-02	7.79e-01
REACTOME ONCOGENIC MAPK SIGNALING	79	2.73e-01	-7.14e-02	7.82e-01
REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	62	2.73e-01	-8.05e-02	7.82e-01
REACTOME P75NTR REGULATES AXONOGENESIS	9	2.74e-01	-2.10e-01	7.83e-01
REACTOME HDL REMODELING	10	2.75e-01	2.00e-01	7.83e-01
REACTOME DISEASES ASSOCIATED WITH SURFACTANT METABOLISM	9	2.75e-01	2.10e-01	7.83e-01
REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN	37	2.77e-01	-1.03e-01	7.86e-01
REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	12	2.77e-01	1.81e-01	7.86e-01
REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3	679	2.78e-01	2.44e-02	7.86e-01
REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING	34	2.78e-01	-1.07e-01	7.86e-01
REACTOME FRUCTOSE METABOLISM	7	2.79e-01	-2.36e-01	7.86e-01
REACTOME MET INTERACTS WITH TNS PROTEINS	5	2.80e-01	-2.79e-01	7.88e-01
REACTOME SIGNALING BY FGFR IN DISEASE	62	2.81e-01	7.92e-02	7.88e-01
REACTOME NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION	193	2.81e-01	-4.50e-02	7.88e-01
REACTOME M PHASE	398	2.81e-01	3.15e-02	7.89e-01
REACTOME MRNA EDITING C TO U CONVERSION	8	2.83e-01	-2.19e-01	7.89e-01
REACTOME ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY	10	2.83e-01	1.96e-01	7.89e-01
REACTOME SIGNALING BY ERBB2 IN CANCER	26	2.83e-01	1.22e-01	7.89e-01
REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE	93	2.84e-01	-6.43e-02	7.89e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST	18	2.84e-01	-1.46e-01	7.89e-01
REACTOME NEUROTRANSMITTER CLEARANCE	9	2.85e-01	-2.06e-01	7.91e-01
REACTOME N GLYCAN ANTENNAE ELONGATION	15	2.87e-01	-1.59e-01	7.94e-01
REACTOME SIGNALING BY FGFR2	72	2.87e-01	7.25e-02	7.94e-01
REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	16	2.88e-01	1.53e-01	7.94e-01
REACTOME GLUTAMATE AND GLUTAMINE METABOLISM	13	2.88e-01	-1.70e-01	7.94e-01
REACTOME HIV ELONGATION ARREST AND RECOVERY	33	2.89e-01	1.07e-01	7.95e-01
REACTOME PP2A MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS	6	2.90e-01	-2.49e-01	7.96e-01
REACTOME DEFECTS IN VITAMIN AND COFACTOR METABOLISM	21	2.90e-01	-1.33e-01	7.96e-01
REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL	13	2.92e-01	-1.69e-01	7.96e-01
REACTOME ABACAVIR TRANSMEMBRANE TRANSPORT	5	2.92e-01	-2.72e-01	7.96e-01
REACTOME PROLACTIN RECEPTOR SIGNALING	15	2.92e-01	1.57e-01	7.96e-01
REACTOME EPHRIN SIGNALING	17	2.94e-01	-1.47e-01	8.00e-01
REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	31	2.97e-01	-1.08e-01	8.05e-01
REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	9	2.97e-01	2.01e-01	8.05e-01
REACTOME CONDENSATION OF PROMETAPHASE CHROMOSOMES	11	2.98e-01	1.81e-01	8.07e-01
REACTOME COLLAGEN DEGRADATION	61	2.98e-01	-7.70e-02	8.07e-01
REACTOME TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS	36	3.02e-01	-9.94e-02	8.12e-01
REACTOME SUMOYLATION	179	3.02e-01	-4.47e-02	8.12e-01
REACTOME PROCESSING OF DNA DOUBLE STRAND BREAK ENDS	93	3.03e-01	6.18e-02	8.12e-01
REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	160	3.04e-01	-4.71e-02	8.12e-01
REACTOME FORMATION OF TC NER PRE INCISION COMPLEX	51	3.04e-01	8.33e-02	8.12e-01
REACTOME RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION	22	3.04e-01	-1.27e-01	8.12e-01
REACTOME LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS	19	3.04e-01	1.36e-01	8.12e-01
REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	16	3.04e-01	-1.48e-01	8.12e-01
REACTOME TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS	26	3.07e-01	1.16e-01	8.13e-01
REACTOME PHASE 3 RAPID REPOLARISATION	8	3.07e-01	-2.09e-01	8.13e-01
REACTOME G0 AND EARLY G1	27	3.07e-01	-1.14e-01	8.13e-01
REACTOME SIGNALING BY FGFR4	40	3.07e-01	9.33e-02	8.13e-01
REACTOME SIGNALING BY FGFR	85	3.07e-01	6.40e-02	8.13e-01
REACTOME RHOJ GTPASE CYCLE	51	3.08e-01	-8.26e-02	8.13e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH RAS	9	3.08e-01	1.96e-01	8.13e-01
REACTOME INTERLEUKIN 1 FAMILY SIGNALING	146	3.09e-01	4.87e-02	8.15e-01
REACTOME REGULATION OF TP53 EXPRESSION AND DEGRADATION	37	3.10e-01	-9.65e-02	8.15e-01
REACTOME SIGNAL ATTENUATION	10	3.10e-01	-1.85e-01	8.15e-01
REACTOME METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION	15	3.11e-01	-1.51e-01	8.15e-01
REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND	21	3.13e-01	1.27e-01	8.20e-01
REACTOME PEROXISOMAL LIPID METABOLISM	28	3.15e-01	-1.10e-01	8.23e-01
REACTOME RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION	8	3.16e-01	-2.05e-01	8.23e-01
REACTOME CYTOCHROME C MEDIATED APOPTOTIC RESPONSE	12	3.16e-01	1.67e-01	8.23e-01
REACTOME ROBO RECEPTORS BIND AKAP5	9	3.19e-01	-1.92e-01	8.29e-01
REACTOME ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS	87	3.20e-01	-6.17e-02	8.31e-01
REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES	34	3.24e-01	-9.77e-02	8.40e-01
REACTOME CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION	11	3.25e-01	-1.71e-01	8.41e-01
REACTOME TRAFFICKING OF AMPA RECEPTORS	29	3.25e-01	-1.06e-01	8.41e-01
REACTOME BIOTIN TRANSPORT AND METABOLISM	10	3.26e-01	-1.79e-01	8.42e-01
REACTOME BH3 ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI APOPTOTIC BCL 2 MEMBERS	9	3.27e-01	-1.89e-01	8.43e-01
REACTOME CHREBP ACTIVATES METABOLIC GENE EXPRESSION	8	3.28e-01	-2.00e-01	8.43e-01
REACTOME SUMOYLATION OF DNA METHYLATION PROTEINS	16	3.29e-01	-1.41e-01	8.43e-01
REACTOME PI3K EVENTS IN ERBB2 SIGNALING	16	3.29e-01	1.41e-01	8.43e-01
REACTOME RELAXIN RECEPTORS	8	3.30e-01	-1.99e-01	8.46e-01
REACTOME SIGNALING BY ALK	26	3.33e-01	1.10e-01	8.47e-01
REACTOME ER QUALITY CONTROL COMPARTMENT ERQC	21	3.33e-01	1.22e-01	8.47e-01
REACTOME GERM LAYER FORMATION AT GASTRULATION	17	3.33e-01	1.36e-01	8.47e-01
REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	9	3.33e-01	-1.86e-01	8.47e-01
REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	22	3.33e-01	-1.19e-01	8.47e-01
REACTOME SIGNALING BY FGFR3	39	3.34e-01	8.94e-02	8.47e-01
REACTOME EGFR DOWNREGULATION	30	3.34e-01	1.02e-01	8.47e-01
REACTOME CHYLOMICRON REMODELING	10	3.35e-01	1.76e-01	8.47e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL	15	3.36e-01	-1.44e-01	8.47e-01
REACTOME LAMININ INTERACTIONS	28	3.36e-01	1.05e-01	8.47e-01
REACTOME OTHER SEMAPHORIN INTERACTIONS	18	3.37e-01	-1.31e-01	8.48e-01
REACTOME TRNA PROCESSING	105	3.38e-01	5.41e-02	8.50e-01
REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	30	3.39e-01	-1.01e-01	8.50e-01
REACTOME RAF ACTIVATION	33	3.40e-01	-9.60e-02	8.50e-01
REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY	5	3.40e-01	-2.46e-01	8.50e-01
REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS	29	3.41e-01	1.02e-01	8.50e-01
REACTOME SARS COV 2 INFECTION	281	3.41e-01	3.30e-02	8.50e-01
REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	76	3.42e-01	-6.31e-02	8.51e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE	5	3.43e-01	-2.45e-01	8.52e-01
REACTOME SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS	14	3.43e-01	-1.46e-01	8.52e-01
REACTOME PI3K AKT SIGNALING IN CANCER	103	3.45e-01	5.39e-02	8.55e-01
REACTOME DISEASES OF CARBOHYDRATE METABOLISM	31	3.45e-01	-9.79e-02	8.55e-01
REACTOME PTK6 EXPRESSION	5	3.46e-01	-2.44e-01	8.55e-01
REACTOME RAB REGULATION OF TRAFFICKING	110	3.46e-01	-5.20e-02	8.55e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY	19	3.47e-01	1.25e-01	8.55e-01
REACTOME IRAK4 DEFICIENCY TLR2 4	17	3.48e-01	-1.31e-01	8.55e-01
REACTOME PROCESSING OF INTRONLESS PRE MRNAS	19	3.49e-01	1.24e-01	8.55e-01
REACTOME GLUCOSE METABOLISM	90	3.49e-01	-5.71e-02	8.55e-01
REACTOME UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN	6	3.49e-01	-2.21e-01	8.55e-01
REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	23	3.50e-01	1.13e-01	8.55e-01
REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS	83	3.50e-01	-5.93e-02	8.55e-01
REACTOME RSK ACTIVATION	5	3.52e-01	-2.40e-01	8.56e-01
REACTOME ION TRANSPORT BY P TYPE ATPASES	51	3.53e-01	-7.52e-02	8.56e-01
REACTOME DAP12 INTERACTIONS	37	3.53e-01	8.82e-02	8.56e-01
REACTOME RIBAVIRIN ADME	11	3.53e-01	-1.62e-01	8.56e-01
REACTOME ION HOMEOSTASIS	52	3.53e-01	-7.45e-02	8.56e-01
REACTOME FORMATION OF APOPTOSOME	10	3.57e-01	1.68e-01	8.62e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH CDC42	19	3.57e-01	-1.22e-01	8.62e-01
REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS	43	3.59e-01	-8.08e-02	8.62e-01
REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	14	3.60e-01	1.41e-01	8.62e-01
REACTOME PYRIMIDINE SALVAGE	10	3.60e-01	-1.67e-01	8.62e-01
REACTOME MRNA EDITING	10	3.61e-01	-1.67e-01	8.62e-01
REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	15	3.62e-01	-1.36e-01	8.62e-01
REACTOME ACTIVATION OF PPARGC1A PGC 1ALPHA BY PHOSPHORYLATION	10	3.62e-01	1.66e-01	8.62e-01
REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	12	3.63e-01	1.52e-01	8.62e-01
REACTOME KERATINIZATION	210	3.63e-01	3.64e-02	8.62e-01
REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	118	3.63e-01	4.84e-02	8.62e-01
REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES	14	3.64e-01	-1.40e-01	8.62e-01
REACTOME DISEASES OF GLYCOSYLATION	137	3.64e-01	4.49e-02	8.62e-01
REACTOME PHOSPHORYLATION OF THE APC C	20	3.65e-01	-1.17e-01	8.62e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY DVL INTERACTING PROTEINS	5	3.65e-01	-2.34e-01	8.62e-01
REACTOME FRUCTOSE CATABOLISM	5	3.65e-01	-2.34e-01	8.62e-01
REACTOME DEFECTS IN BIOTIN BTN METABOLISM	8	3.65e-01	-1.85e-01	8.62e-01
REACTOME MITOCHONDRIAL BIOGENESIS	87	3.66e-01	5.61e-02	8.62e-01
REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	19	3.67e-01	-1.20e-01	8.62e-01
REACTOME ERKS ARE INACTIVATED	13	3.67e-01	-1.45e-01	8.62e-01
REACTOME P75NTR SIGNALS VIA NF KB	15	3.67e-01	1.35e-01	8.62e-01
REACTOME CD28 DEPENDENT VAV1 PATHWAY	11	3.67e-01	1.57e-01	8.62e-01
REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS	188	3.67e-01	3.81e-02	8.62e-01
REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS	19	3.69e-01	-1.19e-01	8.64e-01
REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	129	3.70e-01	-4.57e-02	8.64e-01
REACTOME APOPTOTIC FACTOR MEDIATED RESPONSE	19	3.71e-01	1.19e-01	8.66e-01
REACTOME DIGESTION OF DIETARY LIPID	7	3.71e-01	-1.95e-01	8.66e-01
REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	111	3.73e-01	4.90e-02	8.67e-01
REACTOME SYNTHESIS OF 15 EICOSATETRAENOIC ACID DERIVATIVES	6	3.73e-01	2.10e-01	8.67e-01
REACTOME PEPTIDE HORMONE METABOLISM	84	3.74e-01	5.61e-02	8.67e-01
REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE	71	3.74e-01	-6.10e-02	8.67e-01
REACTOME C TYPE LECTIN RECEPTORS CLRS	136	3.74e-01	4.41e-02	8.67e-01
REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	16	3.75e-01	1.28e-01	8.67e-01
REACTOME SARS COV 2 TARGETS PDZ PROTEINS IN CELL CELL JUNCTION	5	3.76e-01	2.29e-01	8.67e-01
REACTOME REGULATION OF RUNX1 EXPRESSION AND ACTIVITY	17	3.78e-01	-1.24e-01	8.68e-01
REACTOME POLO LIKE KINASE MEDIATED EVENTS	16	3.78e-01	-1.27e-01	8.68e-01
REACTOME HIV TRANSCRIPTION ELONGATION	42	3.79e-01	7.85e-02	8.68e-01
REACTOME HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS	7	3.79e-01	-1.92e-01	8.68e-01
REACTOME FORMATION OF XYLULOSE 5 PHOSPHATE	5	3.81e-01	-2.26e-01	8.68e-01
REACTOME ORGANIC CATION TRANSPORT	10	3.81e-01	-1.60e-01	8.68e-01
REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING	29	3.82e-01	-9.38e-02	8.68e-01
REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS	55	3.82e-01	6.81e-02	8.68e-01
REACTOME CYCLIN D ASSOCIATED EVENTS IN G1	46	3.82e-01	-7.44e-02	8.68e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS	9	3.82e-01	-1.68e-01	8.68e-01
REACTOME SIGNALLING TO RAS	20	3.83e-01	1.13e-01	8.68e-01
REACTOME REGULATION OF NPAS4 MRNA TRANSLATION	9	3.83e-01	-1.68e-01	8.68e-01
REACTOME CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY	12	3.84e-01	1.45e-01	8.68e-01
REACTOME TNF SIGNALING	54	3.84e-01	-6.85e-02	8.68e-01
REACTOME PLATELET HOMEOSTASIS	85	3.84e-01	-5.46e-02	8.68e-01
REACTOME NEGATIVE REGULATION OF MET ACTIVITY	20	3.84e-01	1.12e-01	8.68e-01
REACTOME REGULATION OF PTEN GENE TRANSCRIPTION	59	3.87e-01	-6.52e-02	8.72e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX IN CANCER	8	3.89e-01	-1.76e-01	8.76e-01
REACTOME ACTIVATION OF CASPASES THROUGH APOPTOSOME MEDIATED CLEAVAGE	5	3.91e-01	2.22e-01	8.77e-01
REACTOME FERTILIZATION	26	3.91e-01	-9.73e-02	8.77e-01
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	81	3.92e-01	-5.50e-02	8.79e-01
REACTOME HEME BIOSYNTHESIS	13	3.93e-01	1.37e-01	8.80e-01
REACTOME COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC	52	3.94e-01	-6.84e-02	8.80e-01
REACTOME ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM	12	3.96e-01	1.42e-01	8.80e-01
REACTOME FLT3 SIGNALING IN DISEASE	28	3.96e-01	9.27e-02	8.80e-01
REACTOME SYNTHESIS OF PIPS AT THE ER MEMBRANE	5	3.96e-01	-2.19e-01	8.80e-01
REACTOME VESICLE MEDIATED TRANSPORT	642	3.96e-01	-1.96e-02	8.80e-01
REACTOME PROTEIN REPAIR	6	3.96e-01	-2.00e-01	8.80e-01
REACTOME ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS	5	3.97e-01	2.19e-01	8.80e-01
REACTOME HDL ASSEMBLY	8	3.97e-01	-1.73e-01	8.80e-01
REACTOME BETA OXIDATION OF PRISTANOYL COA	9	3.99e-01	-1.62e-01	8.82e-01
REACTOME INITIATION OF NUCLEAR ENVELOPE NE REFORMATION	18	4.00e-01	-1.15e-01	8.82e-01
REACTOME ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS	41	4.00e-01	-7.60e-02	8.82e-01
REACTOME ENOS ACTIVATION	11	4.01e-01	-1.46e-01	8.82e-01
REACTOME SIGNALING BY PDGF	57	4.02e-01	6.42e-02	8.82e-01
REACTOME RAB GERANYLGERANYLATION	57	4.02e-01	6.41e-02	8.82e-01
REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	24	4.03e-01	-9.85e-02	8.82e-01
REACTOME GLYCOSAMINOGLYCAN METABOLISM	118	4.04e-01	-4.45e-02	8.82e-01
REACTOME ENDOSOMAL VACUOLAR PATHWAY	11	4.05e-01	1.45e-01	8.82e-01
REACTOME THE ACTIVATION OF ARYLSULFATASES	8	4.06e-01	-1.70e-01	8.82e-01
REACTOME TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS	29	4.06e-01	-8.91e-02	8.82e-01
REACTOME ERYTHROPOIETIN ACTIVATES RAS	14	4.06e-01	1.28e-01	8.82e-01
REACTOME SPHINGOLIPID METABOLISM	84	4.08e-01	-5.22e-02	8.82e-01
REACTOME RUNX3 REGULATES WNT SIGNALING	8	4.08e-01	1.69e-01	8.82e-01
REACTOME PYRUVATE METABOLISM	29	4.09e-01	8.87e-02	8.82e-01
REACTOME SIGNALING BY FGFR2 IIIA TM	19	4.09e-01	1.09e-01	8.82e-01
REACTOME PTEN REGULATION	135	4.09e-01	4.12e-02	8.82e-01
REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	26	4.09e-01	-9.35e-02	8.82e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1	16	4.09e-01	-1.19e-01	8.82e-01
REACTOME TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE	20	4.09e-01	-1.07e-01	8.82e-01
REACTOME EXTENSION OF TELOMERES	49	4.10e-01	6.81e-02	8.82e-01
REACTOME SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS	43	4.10e-01	-7.26e-02	8.82e-01
REACTOME DRUG MEDIATED INHIBITION OF CDK4 CDK6 ACTIVITY	5	4.11e-01	-2.12e-01	8.82e-01
REACTOME SIGNALLING TO ERKS	34	4.11e-01	8.14e-02	8.82e-01
REACTOME EGFR TRANSACTIVATION BY GASTRIN	9	4.12e-01	1.58e-01	8.82e-01
REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	35	4.14e-01	7.98e-02	8.82e-01
REACTOME CD209 DC SIGN SIGNALING	20	4.14e-01	-1.05e-01	8.82e-01
REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX	15	4.15e-01	-1.22e-01	8.82e-01
REACTOME CYTOSOLIC TRNA AMINOACYLATION	22	4.15e-01	-1.00e-01	8.82e-01
REACTOME PD 1 SIGNALING	21	4.15e-01	-1.03e-01	8.82e-01
REACTOME SIGNALING BY NTRK3 TRKC	17	4.16e-01	1.14e-01	8.82e-01
REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES	77	4.17e-01	5.35e-02	8.82e-01
REACTOME INWARDLY RECTIFYING K CHANNELS	35	4.17e-01	-7.92e-02	8.82e-01
REACTOME TACHYKININ RECEPTORS BIND TACHYKININS	5	4.17e-01	2.09e-01	8.82e-01
REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS	17	4.17e-01	1.14e-01	8.82e-01
REACTOME LOSS OF FUNCTION OF SMAD2 3 IN CANCER	7	4.18e-01	-1.77e-01	8.82e-01
REACTOME RHOBTB GTPASE CYCLE	34	4.18e-01	8.03e-02	8.82e-01
REACTOME MET PROMOTES CELL MOTILITY	41	4.18e-01	7.30e-02	8.82e-01
REACTOME EARLY PHASE OF HIV LIFE CYCLE	14	4.19e-01	1.25e-01	8.82e-01
REACTOME OVARIAN TUMOR DOMAIN PROTEASES	36	4.21e-01	-7.74e-02	8.85e-01
REACTOME SIGNALING BY EGFR	49	4.22e-01	6.63e-02	8.85e-01
REACTOME MICRORNA MIRNA BIOGENESIS	25	4.22e-01	9.28e-02	8.85e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES	8	4.23e-01	-1.63e-01	8.87e-01
REACTOME CALCITONIN LIKE LIGAND RECEPTORS	10	4.25e-01	-1.46e-01	8.88e-01
REACTOME PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING	11	4.25e-01	1.39e-01	8.88e-01
REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	52	4.26e-01	6.39e-02	8.88e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES	16	4.26e-01	1.15e-01	8.89e-01
REACTOME VXPX CARGO TARGETING TO CILIUM	20	4.27e-01	-1.03e-01	8.89e-01
REACTOME ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY	5	4.28e-01	2.05e-01	8.89e-01
REACTOME NOSTRIN MEDIATED ENOS TRAFFICKING	5	4.28e-01	-2.05e-01	8.89e-01
REACTOME PTK6 REGULATES CELL CYCLE	6	4.29e-01	-1.87e-01	8.89e-01
REACTOME SIGNALING BY HIPPO	19	4.32e-01	1.04e-01	8.93e-01
REACTOME INTERLEUKIN 6 FAMILY SIGNALING	24	4.32e-01	-9.26e-02	8.93e-01
REACTOME EPHB MEDIATED FORWARD SIGNALING	41	4.33e-01	7.08e-02	8.93e-01
REACTOME HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE	43	4.33e-01	6.91e-02	8.93e-01
REACTOME CYTOPROTECTION BY HMOX1	59	4.33e-01	5.90e-02	8.93e-01
REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM	23	4.35e-01	9.40e-02	8.94e-01
REACTOME DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS	25	4.35e-01	9.02e-02	8.94e-01
REACTOME SCAVENGING OF HEME FROM PLASMA	13	4.36e-01	1.25e-01	8.94e-01
REACTOME PHASE 1 INACTIVATION OF FAST NA CHANNELS	6	4.37e-01	1.83e-01	8.94e-01
REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	22	4.37e-01	9.57e-02	8.94e-01
REACTOME MYOGENESIS	29	4.37e-01	8.33e-02	8.94e-01
REACTOME NOD1 2 SIGNALING PATHWAY	33	4.38e-01	7.80e-02	8.95e-01
REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP	41	4.40e-01	-6.97e-02	8.95e-01
REACTOME AURKA ACTIVATION BY TPX2	69	4.42e-01	-5.35e-02	8.95e-01
REACTOME POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION	27	4.42e-01	-8.54e-02	8.95e-01
REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	12	4.43e-01	-1.28e-01	8.95e-01
REACTOME COLLAGEN CHAIN TRIMERIZATION	42	4.43e-01	6.85e-02	8.95e-01
REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	35	4.43e-01	-7.49e-02	8.95e-01
REACTOME ACTIVATION OF AMPK DOWNSTREAM OF NMDARS	28	4.43e-01	-8.38e-02	8.95e-01
REACTOME METABOLISM OF COFACTORS	19	4.43e-01	-1.02e-01	8.95e-01
REACTOME DEFECTIVE CHSY1 CAUSES TPBS	7	4.44e-01	1.67e-01	8.95e-01
REACTOME MET ACTIVATES RAP1 AND RAC1	11	4.44e-01	-1.33e-01	8.95e-01
REACTOME NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	19	4.46e-01	-1.01e-01	8.96e-01
REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES	18	4.46e-01	-1.04e-01	8.96e-01
REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	29	4.47e-01	8.17e-02	8.96e-01
REACTOME DOPAMINE RECEPTORS	5	4.47e-01	1.96e-01	8.96e-01
REACTOME CELLULAR HEXOSE TRANSPORT	21	4.47e-01	9.59e-02	8.96e-01
REACTOME RUNX3 REGULATES BCL2L11 BIM TRANSCRIPTION	5	4.48e-01	1.96e-01	8.96e-01
REACTOME HYDROLYSIS OF LPC	9	4.48e-01	-1.46e-01	8.96e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX	91	4.49e-01	-4.59e-02	8.96e-01
REACTOME GLYCOGEN METABOLISM	22	4.50e-01	-9.30e-02	8.96e-01
REACTOME SYNTHESIS OF DOLICHYL PHOSPHATE	6	4.51e-01	-1.78e-01	8.96e-01
REACTOME MATURATION OF SARS COV 1 SPIKE PROTEIN	5	4.51e-01	1.95e-01	8.96e-01
REACTOME RECYCLING PATHWAY OF L1	43	4.52e-01	-6.64e-02	8.96e-01
REACTOME HDL CLEARANCE	5	4.52e-01	-1.94e-01	8.96e-01
REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY	25	4.53e-01	-8.67e-02	8.96e-01
REACTOME HDR THROUGH MMEJ ALT NHEJ	12	4.54e-01	-1.25e-01	8.96e-01
REACTOME MITOTIC G2 G2 M PHASES	194	4.54e-01	3.12e-02	8.96e-01
REACTOME BETA CATENIN PHOSPHORYLATION CASCADE	16	4.55e-01	-1.08e-01	8.96e-01
REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	38	4.55e-01	-7.00e-02	8.96e-01
REACTOME SUMOYLATION OF INTRACELLULAR RECEPTORS	29	4.55e-01	-8.01e-02	8.96e-01
REACTOME SIGNALING BY FLT3 ITD AND TKD MUTANTS	16	4.56e-01	1.08e-01	8.96e-01
REACTOME SIGNALING BY NOTCH1	69	4.58e-01	-5.16e-02	8.96e-01
REACTOME FATTY ACYL COA BIOSYNTHESIS	36	4.59e-01	-7.13e-02	8.96e-01
REACTOME NEGATIVE REGULATION OF MAPK PATHWAY	41	4.59e-01	6.68e-02	8.96e-01
REACTOME DUAL INCISION IN GG NER	39	4.60e-01	-6.84e-02	8.96e-01
REACTOME ATTACHMENT AND ENTRY	16	4.61e-01	1.07e-01	8.96e-01
REACTOME DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A	5	4.61e-01	-1.90e-01	8.96e-01
REACTOME SIGNALING BY MST1	5	4.61e-01	-1.90e-01	8.96e-01
REACTOME REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO	10	4.62e-01	1.34e-01	8.96e-01
REACTOME MISCELLANEOUS TRANSPORT AND BINDING EVENTS	24	4.62e-01	-8.68e-02	8.96e-01
REACTOME RHOB GTPASE CYCLE	67	4.62e-01	-5.19e-02	8.96e-01
REACTOME FLT3 SIGNALING	38	4.63e-01	6.88e-02	8.96e-01
REACTOME DNA DAMAGE RECOGNITION IN GG NER	36	4.63e-01	7.07e-02	8.96e-01
REACTOME SIGNALING BY TGFB FAMILY MEMBERS	119	4.63e-01	-3.89e-02	8.96e-01
REACTOME UPTAKE AND ACTIONS OF BACTERIAL TOXINS	28	4.64e-01	7.99e-02	8.96e-01
REACTOME PURINE CATABOLISM	17	4.65e-01	1.02e-01	8.96e-01
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION	250	4.65e-01	-2.68e-02	8.96e-01
REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX	9	4.67e-01	1.40e-01	8.96e-01
REACTOME O LINKED GLYCOSYLATION OF MUCINS	61	4.67e-01	-5.39e-02	8.96e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12	22	4.67e-01	-8.96e-02	8.96e-01
REACTOME POTASSIUM CHANNELS	102	4.67e-01	-4.17e-02	8.96e-01
REACTOME FGFR2 LIGAND BINDING AND ACTIVATION	19	4.67e-01	9.63e-02	8.96e-01
REACTOME VITAMIN B2 RIBOFLAVIN METABOLISM	7	4.68e-01	-1.58e-01	8.96e-01
REACTOME AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY	8	4.69e-01	1.48e-01	8.96e-01
REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	14	4.70e-01	1.12e-01	8.96e-01
REACTOME HSF1 ACTIVATION	29	4.70e-01	7.76e-02	8.96e-01
REACTOME CGMP EFFECTS	16	4.70e-01	1.04e-01	8.96e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE	5	4.70e-01	-1.86e-01	8.96e-01
REACTOME NEF MEDIATED CD4 DOWN REGULATION	9	4.71e-01	1.39e-01	8.96e-01
REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	45	4.71e-01	-6.21e-02	8.96e-01
REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS	16	4.72e-01	1.04e-01	8.96e-01
REACTOME JOSEPHIN DOMAIN DUBS	11	4.73e-01	1.25e-01	8.96e-01
REACTOME NONHOMOLOGOUS END JOINING NHEJ	64	4.75e-01	5.17e-02	8.96e-01
REACTOME SUPPRESSION OF PHAGOSOMAL MATURATION	13	4.75e-01	1.14e-01	8.96e-01
REACTOME ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT	23	4.77e-01	8.57e-02	8.96e-01
REACTOME NEF MEDIATED CD8 DOWN REGULATION	7	4.77e-01	1.55e-01	8.96e-01
REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER	18	4.77e-01	9.68e-02	8.96e-01
REACTOME TRANSPORT OF FATTY ACIDS	8	4.77e-01	-1.45e-01	8.96e-01
REACTOME SIGNALING BY ERBB4	57	4.78e-01	5.44e-02	8.96e-01
REACTOME DISEASES OF MISMATCH REPAIR MMR	5	4.78e-01	-1.83e-01	8.96e-01
REACTOME LYSOSOME VESICLE BIOGENESIS	33	4.78e-01	-7.14e-02	8.96e-01
REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	10	4.79e-01	1.29e-01	8.96e-01
REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	53	4.80e-01	5.61e-02	8.96e-01
REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	26	4.80e-01	-8.00e-02	8.96e-01
REACTOME AMINO ACID CONJUGATION	9	4.81e-01	-1.36e-01	8.96e-01
REACTOME REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION	9	4.82e-01	-1.35e-01	8.96e-01
REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	14	4.82e-01	1.08e-01	8.96e-01
REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	134	4.84e-01	3.50e-02	8.96e-01
REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS	418	4.84e-01	1.99e-02	8.96e-01
REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	22	4.84e-01	-8.61e-02	8.96e-01
REACTOME DEFECTIVE CHST6 CAUSES MCDC1	8	4.85e-01	1.43e-01	8.96e-01
REACTOME MITOCHONDRIAL CALCIUM ION TRANSPORT	23	4.86e-01	8.39e-02	8.96e-01
REACTOME SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION	8	4.87e-01	-1.42e-01	8.96e-01
REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	19	4.88e-01	9.20e-02	8.96e-01
REACTOME ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS	11	4.88e-01	-1.21e-01	8.96e-01
REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION	6	4.88e-01	1.63e-01	8.96e-01
REACTOME ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES	59	4.89e-01	-5.21e-02	8.96e-01
REACTOME MATURATION OF SARS COV 2 SPIKE PROTEIN	35	4.89e-01	6.76e-02	8.96e-01
REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER	81	4.90e-01	-4.44e-02	8.96e-01
REACTOME APOPTOSIS	173	4.90e-01	3.04e-02	8.96e-01
REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	48	4.91e-01	-5.75e-02	8.96e-01
REACTOME FORMATION OF LATERAL PLATE MESODERM	5	4.91e-01	1.78e-01	8.96e-01
REACTOME INSULIN PROCESSING	24	4.91e-01	8.12e-02	8.96e-01
REACTOME MISMATCH REPAIR	15	4.91e-01	-1.03e-01	8.96e-01
REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	11	4.91e-01	-1.20e-01	8.96e-01
REACTOME FGFR1C LIGAND BINDING AND ACTIVATION	11	4.92e-01	1.20e-01	8.96e-01
REACTOME TERMINATION OF TRANSLESION DNA SYNTHESIS	32	4.93e-01	-7.01e-02	8.96e-01
REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	69	4.93e-01	4.77e-02	8.96e-01
REACTOME TRNA AMINOACYLATION	40	4.93e-01	-6.26e-02	8.96e-01
REACTOME HIV LIFE CYCLE	145	4.93e-01	3.30e-02	8.96e-01
REACTOME BETA OXIDATION OF BUTANOYL COA TO ACETYL COA	5	4.93e-01	-1.77e-01	8.96e-01
REACTOME DNA DAMAGE REVERSAL	8	4.96e-01	-1.39e-01	8.99e-01
REACTOME SIGNALING BY LRP5 MUTANTS	6	4.96e-01	1.60e-01	8.99e-01
REACTOME RHO GTPASE CYCLE	423	4.97e-01	-1.93e-02	9.00e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES	29	4.99e-01	7.25e-02	9.02e-01
REACTOME TERMINAL PATHWAY OF COMPLEMENT	8	4.99e-01	1.38e-01	9.02e-01
REACTOME DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS	19	5.00e-01	8.93e-02	9.02e-01
REACTOME GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION	30	5.01e-01	7.10e-02	9.02e-01
REACTOME SULFUR AMINO ACID METABOLISM	27	5.01e-01	-7.48e-02	9.02e-01
REACTOME DEGRADATION OF CYSTEINE AND HOMOCYSTEINE	15	5.01e-01	-1.00e-01	9.02e-01
REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	17	5.02e-01	9.40e-02	9.02e-01
REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	16	5.03e-01	9.66e-02	9.03e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1	25	5.04e-01	-7.72e-02	9.03e-01
REACTOME SIGNALING BY FGFR1 IN DISEASE	38	5.07e-01	6.23e-02	9.07e-01
REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	15	5.07e-01	-9.89e-02	9.07e-01
REACTOME DNA REPLICATION INITIATION	7	5.07e-01	-1.45e-01	9.07e-01
REACTOME PRE NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM	6	5.09e-01	-1.56e-01	9.08e-01
REACTOME SIGNALING BY ACTIVIN	15	5.11e-01	-9.80e-02	9.09e-01
REACTOME RHO GTPASES ACTIVATE PAKS	19	5.11e-01	-8.71e-02	9.09e-01
REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION	20	5.11e-01	-8.48e-02	9.09e-01
REACTOME SARS COV 1 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS	16	5.12e-01	9.47e-02	9.09e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	14	5.13e-01	-1.01e-01	9.09e-01
REACTOME OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS	8	5.13e-01	-1.34e-01	9.09e-01
REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	31	5.13e-01	-6.78e-02	9.09e-01
REACTOME HISTIDINE CATABOLISM	8	5.15e-01	-1.33e-01	9.10e-01
REACTOME SODIUM CALCIUM EXCHANGERS	11	5.15e-01	1.13e-01	9.10e-01
REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	23	5.17e-01	-7.81e-02	9.11e-01
REACTOME TRANSPORT OF ORGANIC ANIONS	10	5.17e-01	1.18e-01	9.11e-01
REACTOME NICOTINAMIDE SALVAGING	19	5.17e-01	-8.59e-02	9.11e-01
REACTOME EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION	27	5.19e-01	-7.17e-02	9.14e-01
REACTOME ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING	9	5.22e-01	1.23e-01	9.16e-01
REACTOME INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING	103	5.23e-01	3.64e-02	9.16e-01
REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	20	5.23e-01	8.24e-02	9.16e-01
REACTOME ATORVASTATIN ADME	9	5.24e-01	1.23e-01	9.16e-01
REACTOME DIGESTION OF DIETARY CARBOHYDRATE	6	5.24e-01	1.50e-01	9.16e-01
REACTOME BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS	10	5.24e-01	-1.16e-01	9.16e-01
REACTOME POST TRANSCRIPTIONAL SILENCING BY SMALL RNAS	7	5.25e-01	-1.39e-01	9.16e-01
REACTOME ATTACHMENT OF GPI ANCHOR TO UPAR	7	5.26e-01	1.38e-01	9.16e-01
REACTOME AUTOPHAGY	144	5.27e-01	-3.06e-02	9.16e-01
REACTOME DEFECTS IN COBALAMIN B12 METABOLISM	13	5.27e-01	-1.01e-01	9.16e-01
REACTOME TELOMERE C STRAND SYNTHESIS INITIATION	12	5.27e-01	1.06e-01	9.16e-01
REACTOME FORMATION OF AXIAL MESODERM	14	5.27e-01	9.76e-02	9.16e-01
REACTOME CA2 ACTIVATED K CHANNELS	9	5.28e-01	-1.22e-01	9.16e-01
REACTOME SEPARATION OF SISTER CHROMATIDS	184	5.29e-01	2.69e-02	9.17e-01
REACTOME SYNTHESIS OF GDP MANNOSE	5	5.30e-01	-1.62e-01	9.17e-01
REACTOME HSF1 DEPENDENT TRANSACTIVATION	37	5.31e-01	-5.96e-02	9.17e-01
REACTOME HDR THROUGH SINGLE STRAND ANNEALING SSA	37	5.31e-01	5.95e-02	9.17e-01
REACTOME REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION	84	5.31e-01	-3.96e-02	9.17e-01
REACTOME STAT5 ACTIVATION	7	5.32e-01	1.36e-01	9.17e-01
REACTOME LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME	11	5.32e-01	1.09e-01	9.17e-01
REACTOME SURFACTANT METABOLISM	28	5.33e-01	-6.80e-02	9.17e-01
REACTOME CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND	16	5.34e-01	-8.98e-02	9.17e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES	10	5.34e-01	1.14e-01	9.17e-01
REACTOME PECAM1 INTERACTIONS	12	5.36e-01	-1.03e-01	9.19e-01
REACTOME RUNX3 REGULATES YAP1 MEDIATED TRANSCRIPTION	8	5.36e-01	-1.26e-01	9.19e-01
REACTOME ACYL CHAIN REMODELING OF DAG AND TAG	5	5.37e-01	-1.60e-01	9.19e-01
REACTOME SCAVENGING BY CLASS B RECEPTORS	6	5.39e-01	1.45e-01	9.19e-01
REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM	50	5.39e-01	5.02e-02	9.19e-01
REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	14	5.39e-01	9.48e-02	9.19e-01
REACTOME SYNTHESIS OF KETONE BODIES	8	5.39e-01	-1.25e-01	9.19e-01
REACTOME ACETYLCHOLINE REGULATES INSULIN SECRETION	10	5.40e-01	-1.12e-01	9.19e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN	21	5.41e-01	-7.71e-02	9.20e-01
REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ	6	5.42e-01	1.44e-01	9.21e-01
REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	15	5.44e-01	-9.06e-02	9.22e-01
REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC	198	5.44e-01	-2.50e-02	9.22e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	24	5.44e-01	-7.15e-02	9.22e-01
REACTOME WNT MEDIATED ACTIVATION OF DVL	8	5.45e-01	-1.24e-01	9.22e-01
REACTOME RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS	5	5.47e-01	-1.56e-01	9.24e-01
REACTOME FATTY ACID METABOLISM	170	5.47e-01	-2.68e-02	9.24e-01
REACTOME EPH EPHRIN SIGNALING	90	5.48e-01	-3.66e-02	9.24e-01
REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV 1 INFECTION	5	5.49e-01	-1.55e-01	9.24e-01
REACTOME TNFR1 INDUCED PROAPOPTOTIC SIGNALING	23	5.49e-01	-7.22e-02	9.24e-01
REACTOME PLASMA LIPOPROTEIN CLEARANCE	37	5.49e-01	5.69e-02	9.24e-01
REACTOME LDL REMODELING	6	5.53e-01	1.40e-01	9.27e-01
REACTOME SHC1 EVENTS IN EGFR SIGNALING	14	5.53e-01	9.17e-02	9.27e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX	19	5.53e-01	-7.86e-02	9.27e-01
REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS	12	5.56e-01	9.83e-02	9.30e-01
REACTOME MASTL FACILITATES MITOTIC PROGRESSION	10	5.56e-01	1.08e-01	9.30e-01
REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	15	5.57e-01	-8.77e-02	9.31e-01
REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	38	5.57e-01	5.50e-02	9.31e-01
REACTOME TYROSINE CATABOLISM	5	5.58e-01	-1.51e-01	9.31e-01
REACTOME ASSEMBLY OF THE HIV VIRION	16	5.60e-01	-8.42e-02	9.31e-01
REACTOME IRS ACTIVATION	5	5.60e-01	-1.51e-01	9.31e-01
REACTOME TRANSLESION SYNTHESIS BY POLH	19	5.60e-01	7.72e-02	9.31e-01
REACTOME RESPONSE OF MTB TO PHAGOCYTOSIS	22	5.60e-01	7.17e-02	9.31e-01
REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	14	5.61e-01	-8.98e-02	9.31e-01
REACTOME TRAIL SIGNALING	8	5.62e-01	-1.18e-01	9.31e-01
REACTOME NUCLEOTIDE SALVAGE	21	5.62e-01	-7.30e-02	9.31e-01
REACTOME CA2 PATHWAY	62	5.63e-01	-4.25e-02	9.31e-01
REACTOME PROTEIN FOLDING	96	5.63e-01	-3.41e-02	9.31e-01
REACTOME LYSINE CATABOLISM	12	5.65e-01	9.59e-02	9.33e-01
REACTOME MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS	7	5.66e-01	1.25e-01	9.33e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION	45	5.68e-01	4.92e-02	9.33e-01
REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	46	5.68e-01	-4.86e-02	9.33e-01
REACTOME ERYTHROPOIETIN ACTIVATES STAT5	7	5.68e-01	1.25e-01	9.33e-01
REACTOME KINESINS	59	5.69e-01	-4.29e-02	9.33e-01
REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	37	5.69e-01	-5.41e-02	9.33e-01
REACTOME SYNTHESIS OF 5 EICOSATETRAENOIC ACIDS	9	5.69e-01	1.10e-01	9.33e-01
REACTOME ARACHIDONIC ACID METABOLISM	57	5.70e-01	4.35e-02	9.33e-01
REACTOME TRANSLESION SYNTHESIS BY POLK	17	5.70e-01	7.95e-02	9.33e-01
REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	21	5.70e-01	-7.15e-02	9.33e-01
REACTOME GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER	25	5.74e-01	-6.50e-02	9.33e-01
REACTOME INITIAL TRIGGERING OF COMPLEMENT	21	5.74e-01	-7.09e-02	9.33e-01
REACTOME REGULATION BY C FLIP	11	5.74e-01	9.79e-02	9.33e-01
REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL	12	5.74e-01	9.37e-02	9.33e-01
REACTOME DEFECTIVE CHST3 CAUSES SEDCJD	7	5.74e-01	1.23e-01	9.33e-01
REACTOME RAP1 SIGNALLING	16	5.75e-01	-8.11e-02	9.33e-01
REACTOME GENERATION OF SECOND MESSENGER MOLECULES	30	5.80e-01	5.84e-02	9.33e-01
REACTOME HS GAG DEGRADATION	19	5.80e-01	7.33e-02	9.33e-01
REACTOME NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	24	5.80e-01	-6.52e-02	9.33e-01
REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION	26	5.80e-01	-6.26e-02	9.33e-01
REACTOME VLDLR INTERNALISATION AND DEGRADATION	16	5.80e-01	7.98e-02	9.33e-01
REACTOME FGFR3B LIGAND BINDING AND ACTIVATION	7	5.82e-01	-1.20e-01	9.33e-01
REACTOME REGULATION OF PTEN LOCALIZATION	8	5.84e-01	1.12e-01	9.33e-01
REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	8	5.84e-01	1.12e-01	9.33e-01
REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	20	5.84e-01	7.07e-02	9.33e-01
REACTOME INTERLEUKIN 17 SIGNALING	66	5.85e-01	-3.89e-02	9.33e-01
REACTOME SIGNALING BY MAPK MUTANTS	6	5.85e-01	1.29e-01	9.33e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS	11	5.86e-01	-9.48e-02	9.33e-01
REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF	53	5.86e-01	-4.32e-02	9.33e-01
REACTOME SUMO IS TRANSFERRED FROM E1 TO E2 UBE2I UBC9	7	5.87e-01	-1.19e-01	9.33e-01
REACTOME MAP2K AND MAPK ACTIVATION	38	5.87e-01	-5.09e-02	9.33e-01
REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES	21	5.87e-01	6.85e-02	9.33e-01
REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION	145	5.87e-01	2.61e-02	9.33e-01
REACTOME RHO GTPASES ACTIVATE NADPH OXIDASES	21	5.88e-01	6.83e-02	9.33e-01
REACTOME THE NLRP3 INFLAMMASOME	16	5.88e-01	7.81e-02	9.33e-01
REACTOME UPTAKE AND FUNCTION OF ANTHRAX TOXINS	11	5.89e-01	9.41e-02	9.33e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	36	5.89e-01	-5.20e-02	9.33e-01
REACTOME NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION	20	5.90e-01	6.96e-02	9.33e-01
REACTOME SIGNALLING TO P38 VIA RIT AND RIN	5	5.91e-01	1.39e-01	9.33e-01
REACTOME G ALPHA 12 13 SIGNALLING EVENTS	74	5.91e-01	-3.61e-02	9.33e-01
REACTOME DEATH RECEPTOR SIGNALING	143	5.94e-01	-2.58e-02	9.33e-01
REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	51	5.94e-01	-4.31e-02	9.33e-01
REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	91	5.94e-01	-3.23e-02	9.33e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE	8	5.96e-01	-1.08e-01	9.33e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH RAS	8	5.96e-01	1.08e-01	9.33e-01
REACTOME SIGNALING BY BMP	27	5.97e-01	-5.87e-02	9.33e-01
REACTOME MTOR SIGNALLING	40	5.97e-01	4.83e-02	9.33e-01
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION	1356	5.98e-01	-8.55e-03	9.33e-01
REACTOME FATTY ACIDS BOUND TO GPR40 FFAR1 REGULATE INSULIN SECRETION	8	5.99e-01	-1.07e-01	9.33e-01
REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS	66	5.99e-01	3.74e-02	9.33e-01
REACTOME CHAPERONE MEDIATED AUTOPHAGY	20	5.99e-01	6.79e-02	9.33e-01
REACTOME PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1	9	5.99e-01	1.01e-01	9.33e-01
REACTOME INFECTION WITH MYCOBACTERIUM TUBERCULOSIS	25	5.99e-01	6.07e-02	9.33e-01
REACTOME TRIGLYCERIDE BIOSYNTHESIS	12	5.99e-01	-8.76e-02	9.33e-01
REACTOME GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	34	6.00e-01	-5.20e-02	9.33e-01
REACTOME GABA B RECEPTOR ACTIVATION	43	6.00e-01	-4.63e-02	9.33e-01
REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	80	6.01e-01	-3.39e-02	9.33e-01
REACTOME CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA	63	6.01e-01	3.81e-02	9.33e-01
REACTOME DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1	9	6.02e-01	-1.00e-01	9.33e-01
REACTOME ACTIVATION OF MATRIX METALLOPROTEINASES	30	6.03e-01	5.48e-02	9.33e-01
REACTOME VOLTAGE GATED POTASSIUM CHANNELS	42	6.04e-01	-4.63e-02	9.33e-01
REACTOME HEME DEGRADATION	15	6.04e-01	-7.74e-02	9.33e-01
REACTOME NR1H2 AND NR1H3 MEDIATED SIGNALING	46	6.04e-01	-4.42e-02	9.33e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS	5	6.05e-01	-1.34e-01	9.33e-01
REACTOME SMAC XIAP REGULATED APOPTOTIC RESPONSE	7	6.06e-01	1.13e-01	9.33e-01
REACTOME CAMK IV MEDIATED PHOSPHORYLATION OF CREB	10	6.06e-01	-9.43e-02	9.33e-01
REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	30	6.06e-01	-5.44e-02	9.33e-01
REACTOME VITAMIN C ASCORBATE METABOLISM	8	6.06e-01	-1.05e-01	9.33e-01
REACTOME TRANSCRIPTIONAL REGULATION BY TP53	351	6.07e-01	1.60e-02	9.33e-01
REACTOME FBXW7 MUTANTS AND NOTCH1 IN CANCER	5	6.07e-01	1.33e-01	9.33e-01
REACTOME ERK MAPK TARGETS	20	6.07e-01	-6.64e-02	9.33e-01
REACTOME ALPHA DEFENSINS	6	6.07e-01	1.21e-01	9.33e-01
REACTOME PRE NOTCH PROCESSING IN GOLGI	18	6.07e-01	-6.99e-02	9.33e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES	11	6.09e-01	8.92e-02	9.33e-01
REACTOME P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1	6	6.09e-01	-1.21e-01	9.33e-01
REACTOME INTESTINAL ABSORPTION	5	6.10e-01	1.32e-01	9.33e-01
REACTOME NICOTINATE METABOLISM	31	6.10e-01	-5.29e-02	9.33e-01
REACTOME ANDROGEN BIOSYNTHESIS	11	6.11e-01	8.87e-02	9.33e-01
REACTOME INTERLEUKIN 37 SIGNALING	20	6.11e-01	-6.57e-02	9.33e-01
REACTOME SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER	54	6.11e-01	-4.00e-02	9.33e-01
REACTOME IRAK1 RECRUITS IKK COMPLEX	12	6.12e-01	-8.47e-02	9.33e-01
REACTOME VITAMIN D CALCIFEROL METABOLISM	12	6.12e-01	8.45e-02	9.33e-01
REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX	32	6.13e-01	5.17e-02	9.33e-01
REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE	5	6.13e-01	-1.30e-01	9.33e-01
REACTOME SIGNALING BY KIT IN DISEASE	20	6.13e-01	6.53e-02	9.33e-01
REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION	62	6.14e-01	3.70e-02	9.34e-01
REACTOME CHOLESTEROL BIOSYNTHESIS	25	6.16e-01	-5.80e-02	9.35e-01
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES	255	6.16e-01	-1.82e-02	9.35e-01
REACTOME RET SIGNALING	40	6.16e-01	-4.58e-02	9.35e-01
REACTOME SARS COV 2 ACTIVATES MODULATES INNATE AND ADAPTIVE IMMUNE RESPONSES	118	6.18e-01	2.66e-02	9.36e-01
REACTOME ELASTIC FIBRE FORMATION	44	6.18e-01	-4.34e-02	9.36e-01
REACTOME LINOLEIC ACID LA METABOLISM	7	6.19e-01	1.09e-01	9.36e-01
REACTOME LAGGING STRAND SYNTHESIS	19	6.20e-01	-6.57e-02	9.36e-01
REACTOME DIGESTION	17	6.20e-01	-6.94e-02	9.36e-01
REACTOME CLEC7A INFLAMMASOME PATHWAY	6	6.21e-01	-1.17e-01	9.36e-01
REACTOME EGFR INTERACTS WITH PHOSPHOLIPASE C GAMMA	9	6.21e-01	9.52e-02	9.36e-01
REACTOME RHOD GTPASE CYCLE	49	6.24e-01	-4.05e-02	9.39e-01
REACTOME COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING	32	6.24e-01	5.00e-02	9.39e-01
REACTOME SIGNALING BY MRAS COMPLEX MUTANTS	7	6.27e-01	-1.06e-01	9.42e-01
REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	11	6.28e-01	8.43e-02	9.42e-01
REACTOME BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA	5	6.30e-01	-1.24e-01	9.42e-01
REACTOME REGULATION OF PTEN MRNA TRANSLATION	9	6.31e-01	-9.26e-02	9.42e-01
REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	21	6.31e-01	-6.05e-02	9.42e-01
REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	11	6.32e-01	8.35e-02	9.42e-01
REACTOME MITOCHONDRIAL UNCOUPLING	5	6.32e-01	-1.24e-01	9.42e-01
REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS	6	6.33e-01	1.13e-01	9.42e-01
REACTOME PEROXISOMAL PROTEIN IMPORT	62	6.33e-01	-3.51e-02	9.42e-01
REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	9	6.33e-01	9.18e-02	9.42e-01
REACTOME INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS	37	6.33e-01	-4.53e-02	9.42e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH CDK5	6	6.34e-01	1.12e-01	9.42e-01
REACTOME TIGHT JUNCTION INTERACTIONS	29	6.34e-01	5.11e-02	9.42e-01
REACTOME TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION	5	6.34e-01	-1.23e-01	9.42e-01
REACTOME NEUREXINS AND NEUROLIGINS	51	6.36e-01	3.84e-02	9.42e-01
REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION	23	6.37e-01	5.69e-02	9.42e-01
REACTOME INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION	21	6.37e-01	5.95e-02	9.42e-01
REACTOME INTRAFLAGELLAR TRANSPORT	50	6.37e-01	3.86e-02	9.42e-01
REACTOME STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES	16	6.37e-01	-6.81e-02	9.42e-01
REACTOME MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS	17	6.38e-01	6.60e-02	9.42e-01
REACTOME SIGNALING BY CSF1 M CSF IN MYELOID CELLS	30	6.39e-01	4.95e-02	9.42e-01
REACTOME ANCHORING FIBRIL FORMATION	13	6.40e-01	7.49e-02	9.42e-01
REACTOME RUNX2 REGULATES BONE DEVELOPMENT	29	6.40e-01	-5.01e-02	9.42e-01
REACTOME MOLYBDENUM COFACTOR BIOSYNTHESIS	6	6.41e-01	1.10e-01	9.42e-01
REACTOME CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE	49	6.41e-01	3.85e-02	9.42e-01
REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	10	6.42e-01	-8.48e-02	9.43e-01
REACTOME SUMOYLATION OF RNA BINDING PROTEINS	47	6.43e-01	-3.90e-02	9.43e-01
REACTOME VLDL ASSEMBLY	5	6.44e-01	1.20e-01	9.43e-01
REACTOME RUNX3 REGULATES CDKN1A TRANSCRIPTION	7	6.44e-01	-1.01e-01	9.44e-01
REACTOME NEPHRIN FAMILY INTERACTIONS	22	6.45e-01	-5.67e-02	9.45e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES	33	6.47e-01	-4.61e-02	9.45e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION	29	6.48e-01	-4.90e-02	9.46e-01
REACTOME REPRESSION OF WNT TARGET GENES	14	6.48e-01	7.04e-02	9.46e-01
REACTOME ARMS MEDIATED ACTIVATION	7	6.50e-01	9.90e-02	9.46e-01
REACTOME REGULATION OF SIGNALING BY CBL	22	6.50e-01	5.58e-02	9.46e-01
REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS	16	6.51e-01	-6.54e-02	9.46e-01
REACTOME CYP2E1 REACTIONS	10	6.51e-01	-8.26e-02	9.46e-01
REACTOME DECTIN 2 FAMILY	26	6.52e-01	5.11e-02	9.46e-01
REACTOME METHIONINE SALVAGE PATHWAY	6	6.52e-01	-1.06e-01	9.46e-01
REACTOME AMINE LIGAND BINDING RECEPTORS	40	6.53e-01	4.10e-02	9.46e-01
REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS	299	6.54e-01	1.51e-02	9.46e-01
REACTOME INTERLEUKIN RECEPTOR SHC SIGNALING	24	6.54e-01	-5.28e-02	9.46e-01
REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL	41	6.55e-01	4.04e-02	9.46e-01
REACTOME TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE	39	6.55e-01	-4.14e-02	9.46e-01
REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE	9	6.56e-01	8.57e-02	9.47e-01
REACTOME SIGNAL AMPLIFICATION	33	6.56e-01	-4.47e-02	9.47e-01
REACTOME LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX	5	6.57e-01	-1.15e-01	9.47e-01
REACTOME MITOPHAGY	28	6.57e-01	4.84e-02	9.47e-01
REACTOME ESTROGEN BIOSYNTHESIS	6	6.59e-01	1.04e-01	9.48e-01
REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES	39	6.60e-01	-4.08e-02	9.48e-01
REACTOME GLYCOSPHINGOLIPID METABOLISM	39	6.60e-01	-4.07e-02	9.49e-01
REACTOME NCAM1 INTERACTIONS	41	6.61e-01	3.96e-02	9.49e-01
REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS	101	6.62e-01	2.52e-02	9.49e-01
REACTOME RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY	14	6.64e-01	6.70e-02	9.50e-01
REACTOME POLYMERASE SWITCHING	13	6.65e-01	-6.94e-02	9.50e-01
REACTOME CD163 MEDIATING AN ANTI INFLAMMATORY RESPONSE	9	6.65e-01	8.34e-02	9.50e-01
REACTOME RHO GTPASES ACTIVATE FORMINS	136	6.65e-01	-2.15e-02	9.50e-01
REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	67	6.67e-01	-3.04e-02	9.51e-01
REACTOME POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE	25	6.68e-01	4.96e-02	9.51e-01
REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	296	6.68e-01	-1.45e-02	9.51e-01
REACTOME METABOLISM OF AMINE DERIVED HORMONES	17	6.69e-01	-5.99e-02	9.51e-01
REACTOME HORMONE LIGAND BINDING RECEPTORS	12	6.70e-01	7.11e-02	9.51e-01
REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	10	6.70e-01	7.77e-02	9.51e-01
REACTOME FGFR2B LIGAND BINDING AND ACTIVATION	10	6.71e-01	7.76e-02	9.51e-01
REACTOME SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS	16	6.71e-01	6.13e-02	9.51e-01
REACTOME NRCAM INTERACTIONS	6	6.71e-01	1.00e-01	9.51e-01
REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	16	6.72e-01	6.12e-02	9.51e-01
REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION	8	6.73e-01	8.62e-02	9.51e-01
REACTOME UREA CYCLE	9	6.74e-01	-8.10e-02	9.51e-01
REACTOME RUNX3 REGULATES NOTCH SIGNALING	13	6.76e-01	-6.71e-02	9.51e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING	25	6.76e-01	-4.83e-02	9.51e-01
REACTOME TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY	30	6.77e-01	-4.40e-02	9.51e-01
REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	7	6.78e-01	-9.08e-02	9.51e-01
REACTOME MAPK3 ERK1 ACTIVATION	10	6.78e-01	-7.59e-02	9.51e-01
REACTOME VASOPRESSIN LIKE RECEPTORS	5	6.78e-01	-1.07e-01	9.51e-01
REACTOME NUCLEOTIDE BIOSYNTHESIS	14	6.79e-01	6.39e-02	9.51e-01
REACTOME SHC MEDIATED CASCADE FGFR4	19	6.80e-01	5.47e-02	9.51e-01
REACTOME CHL1 INTERACTIONS	9	6.80e-01	7.93e-02	9.51e-01
REACTOME LIPOPHAGY	9	6.81e-01	-7.92e-02	9.51e-01
REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET	8	6.81e-01	8.40e-02	9.51e-01
REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE	109	6.82e-01	2.27e-02	9.51e-01
REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	24	6.82e-01	-4.83e-02	9.51e-01
REACTOME SIGNALING BY RETINOIC ACID	41	6.83e-01	-3.69e-02	9.51e-01
REACTOME NADE MODULATES DEATH SIGNALLING	5	6.84e-01	1.05e-01	9.51e-01
REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX	21	6.84e-01	5.13e-02	9.51e-01
REACTOME LDL CLEARANCE	19	6.84e-01	5.39e-02	9.51e-01
REACTOME COLLAGEN FORMATION	88	6.85e-01	-2.51e-02	9.51e-01
REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	59	6.86e-01	-3.04e-02	9.51e-01
REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB	5	6.86e-01	1.04e-01	9.51e-01
REACTOME FASL CD95L SIGNALING	5	6.87e-01	1.04e-01	9.51e-01
REACTOME CROSSLINKING OF COLLAGEN FIBRILS	16	6.88e-01	5.81e-02	9.51e-01
REACTOME DEFECTIVE RIPK1 MEDIATED REGULATED NECROSIS	7	6.89e-01	8.74e-02	9.51e-01
REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS	18	6.89e-01	-5.44e-02	9.51e-01
REACTOME RA BIOSYNTHESIS PATHWAY	22	6.91e-01	-4.90e-02	9.51e-01
REACTOME G1 S SPECIFIC TRANSCRIPTION	28	6.91e-01	-4.34e-02	9.51e-01
REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	11	6.92e-01	-6.91e-02	9.51e-01
REACTOME DNA STRAND ELONGATION	31	6.92e-01	-4.12e-02	9.51e-01
REACTOME EARLY SARS COV 2 INFECTION EVENTS	34	6.92e-01	-3.93e-02	9.51e-01
REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING	25	6.92e-01	-4.58e-02	9.51e-01
REACTOME KETONE BODY METABOLISM	9	6.92e-01	-7.61e-02	9.51e-01
REACTOME NEDDYLATION	235	6.92e-01	1.50e-02	9.51e-01
REACTOME DISSOLUTION OF FIBRIN CLOT	13	6.93e-01	-6.33e-02	9.51e-01
REACTOME TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT	18	6.93e-01	5.37e-02	9.51e-01
REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4	33	6.93e-01	3.97e-02	9.51e-01
REACTOME RND1 GTPASE CYCLE	41	6.94e-01	-3.55e-02	9.51e-01
REACTOME RHO GTPASES ACTIVATE KTN1	11	6.94e-01	-6.86e-02	9.51e-01
REACTOME PTK6 PROMOTES HIF1A STABILIZATION	6	6.95e-01	-9.23e-02	9.52e-01
REACTOME REGULATION OF NPAS4 GENE EXPRESSION	13	6.96e-01	-6.25e-02	9.52e-01
REACTOME DEADENYLATION DEPENDENT MRNA DECAY	56	6.98e-01	-3.00e-02	9.52e-01
REACTOME RESOLUTION OF SISTER CHROMATID COHESION	120	6.98e-01	-2.05e-02	9.52e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE	11	7.00e-01	-6.72e-02	9.52e-01
REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	26	7.00e-01	4.36e-02	9.52e-01
REACTOME ACTIVATION OF TRKA RECEPTORS	6	7.01e-01	9.06e-02	9.52e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG	7	7.01e-01	8.39e-02	9.52e-01
REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	45	7.01e-01	3.31e-02	9.52e-01
REACTOME PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR	21	7.02e-01	-4.83e-02	9.52e-01
REACTOME SENSING OF DNA DOUBLE STRAND BREAKS	6	7.02e-01	9.01e-02	9.52e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	34	7.03e-01	-3.78e-02	9.52e-01
REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	17	7.03e-01	-5.34e-02	9.52e-01
REACTOME NEURONAL SYSTEM	388	7.03e-01	-1.13e-02	9.52e-01
REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	78	7.05e-01	2.48e-02	9.52e-01
REACTOME VISUAL PHOTOTRANSDUCTION	93	7.06e-01	2.26e-02	9.52e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA	27	7.06e-01	4.19e-02	9.52e-01
REACTOME MINERALOCORTICOID BIOSYNTHESIS	6	7.07e-01	-8.85e-02	9.52e-01
REACTOME NEGATIVE REGULATION OF FLT3	15	7.08e-01	-5.59e-02	9.52e-01
REACTOME METABOLISM OF STEROID HORMONES	35	7.09e-01	3.64e-02	9.52e-01
REACTOME TRNA PROCESSING IN THE NUCLEUS	58	7.10e-01	2.82e-02	9.52e-01
REACTOME FORMATION OF INCISION COMPLEX IN GG NER	40	7.10e-01	-3.39e-02	9.52e-01
REACTOME SOS MEDIATED SIGNALLING	7	7.11e-01	8.09e-02	9.52e-01
REACTOME ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE	9	7.11e-01	7.12e-02	9.52e-01
REACTOME REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS	7	7.12e-01	-8.05e-02	9.52e-01
REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING	30	7.13e-01	3.88e-02	9.52e-01
REACTOME INTERLEUKIN 12 SIGNALING	43	7.13e-01	-3.24e-02	9.52e-01
REACTOME PEPTIDE LIGAND BINDING RECEPTORS	188	7.14e-01	-1.55e-02	9.52e-01
REACTOME RUNX2 REGULATES CHONDROCYTE MATURATION	5	7.14e-01	-9.46e-02	9.52e-01
REACTOME INTERLEUKIN 20 FAMILY SIGNALING	25	7.14e-01	-4.23e-02	9.52e-01
REACTOME RHOA GTPASE CYCLE	142	7.14e-01	-1.78e-02	9.52e-01
REACTOME REGULATION OF LIPID METABOLISM BY PPARALPHA	115	7.15e-01	1.97e-02	9.52e-01
REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE	277	7.15e-01	1.27e-02	9.52e-01
REACTOME RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX	29	7.15e-01	3.91e-02	9.52e-01
REACTOME INTERLEUKIN 2 FAMILY SIGNALING	40	7.15e-01	-3.33e-02	9.52e-01
REACTOME DISEASES OF METABOLISM	237	7.16e-01	-1.37e-02	9.52e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD4	15	7.16e-01	-5.42e-02	9.52e-01
REACTOME CRMPS IN SEMA3A SIGNALING	15	7.18e-01	5.39e-02	9.53e-01
REACTOME NUCLEOTIDE CATABOLISM	35	7.18e-01	-3.52e-02	9.54e-01
REACTOME DEFECTIVE CHST14 CAUSES EDS MUSCULOCONTRACTURAL TYPE	7	7.20e-01	7.82e-02	9.54e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES	61	7.20e-01	2.65e-02	9.54e-01
REACTOME TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA	36	7.20e-01	-3.45e-02	9.54e-01
REACTOME SUMOYLATION OF SUMOYLATION PROTEINS	35	7.22e-01	-3.47e-02	9.54e-01
REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS	6	7.24e-01	8.33e-02	9.54e-01
REACTOME REDUCTION OF CYTOSOLIC CA LEVELS	11	7.24e-01	6.15e-02	9.54e-01
REACTOME REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS	15	7.24e-01	-5.26e-02	9.54e-01
REACTOME SPERM MOTILITY AND TAXES	9	7.24e-01	-6.79e-02	9.54e-01
REACTOME IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN	5	7.24e-01	-9.11e-02	9.54e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2	13	7.25e-01	5.64e-02	9.54e-01
REACTOME GASTRULATION	49	7.25e-01	2.90e-02	9.54e-01
REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	32	7.25e-01	-3.59e-02	9.54e-01
REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS	5	7.27e-01	-9.03e-02	9.54e-01
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION	361	7.27e-01	-1.07e-02	9.55e-01
REACTOME HDR THROUGH HOMOLOGOUS RECOMBINATION HRR	66	7.28e-01	-2.47e-02	9.55e-01
REACTOME NUCLEAR IMPORT OF REV PROTEIN	34	7.29e-01	-3.43e-02	9.55e-01
REACTOME FCGR ACTIVATION	11	7.29e-01	-6.02e-02	9.55e-01
REACTOME RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES TREGS	9	7.30e-01	6.65e-02	9.55e-01
REACTOME INTERLEUKIN 15 SIGNALING	13	7.33e-01	5.47e-02	9.57e-01
REACTOME SHC MEDIATED CASCADE FGFR3	17	7.34e-01	4.77e-02	9.57e-01
REACTOME SIGNALING BY NOTCH3	48	7.34e-01	-2.84e-02	9.57e-01
REACTOME TRIGLYCERIDE METABOLISM	35	7.34e-01	-3.32e-02	9.57e-01
REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES	7	7.35e-01	-7.39e-02	9.57e-01
REACTOME MET ACTIVATES PI3K AKT SIGNALING	6	7.35e-01	7.99e-02	9.57e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS	15	7.37e-01	-5.01e-02	9.58e-01
REACTOME INTEGRIN CELL SURFACE INTERACTIONS	83	7.38e-01	-2.12e-02	9.58e-01
REACTOME SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX	15	7.38e-01	-4.98e-02	9.58e-01
REACTOME ACTIVATION OF SMO	18	7.39e-01	4.54e-02	9.58e-01
REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	13	7.39e-01	-5.33e-02	9.58e-01
REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION	35	7.40e-01	3.25e-02	9.58e-01
REACTOME RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA	7	7.40e-01	-7.23e-02	9.59e-01
REACTOME SELECTIVE AUTOPHAGY	79	7.42e-01	-2.15e-02	9.59e-01
REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	18	7.42e-01	4.48e-02	9.59e-01
REACTOME CTLA4 INHIBITORY SIGNALING	21	7.43e-01	-4.14e-02	9.59e-01
REACTOME STIMULI SENSING CHANNELS	100	7.44e-01	-1.89e-02	9.59e-01
REACTOME INLA MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS	9	7.44e-01	6.29e-02	9.59e-01
REACTOME NRAGE SIGNALS DEATH THROUGH JNK	53	7.44e-01	2.59e-02	9.59e-01
REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	20	7.46e-01	-4.19e-02	9.59e-01
REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	29	7.47e-01	-3.47e-02	9.59e-01
REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS	15	7.47e-01	-4.81e-02	9.59e-01
REACTOME CIPROFLOXACIN ADME	5	7.48e-01	8.30e-02	9.59e-01
REACTOME CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN	45	7.48e-01	-2.76e-02	9.59e-01
REACTOME UNFOLDED PROTEIN RESPONSE UPR	88	7.48e-01	1.98e-02	9.59e-01
REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	19	7.49e-01	4.25e-02	9.59e-01
REACTOME WAX AND PLASMALOGEN BIOSYNTHESIS	5	7.49e-01	-8.27e-02	9.59e-01
REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	49	7.50e-01	-2.63e-02	9.59e-01
REACTOME SIALIC ACID METABOLISM	33	7.50e-01	-3.20e-02	9.59e-01
REACTOME REGULATION OF MECP2 EXPRESSION AND ACTIVITY	30	7.50e-01	-3.36e-02	9.59e-01
REACTOME NEUROFASCIN INTERACTIONS	6	7.52e-01	7.45e-02	9.60e-01
REACTOME GAB1 SIGNALOSOME	17	7.53e-01	4.40e-02	9.60e-01
REACTOME RHOG GTPASE CYCLE	71	7.54e-01	-2.15e-02	9.60e-01
REACTOME INTERFERON ALPHA BETA SIGNALING	70	7.55e-01	-2.16e-02	9.60e-01
REACTOME SIGNALING BY ERBB2	50	7.55e-01	-2.55e-02	9.60e-01
REACTOME GP1B IX V ACTIVATION SIGNALLING	11	7.56e-01	5.42e-02	9.60e-01
REACTOME RAF INDEPENDENT MAPK1 3 ACTIVATION	22	7.56e-01	-3.82e-02	9.60e-01
REACTOME SHC RELATED EVENTS TRIGGERED BY IGF1R	9	7.56e-01	5.97e-02	9.60e-01
REACTOME ROLE OF ABL IN ROBO SLIT SIGNALING	8	7.57e-01	6.32e-02	9.60e-01
REACTOME DNA DOUBLE STRAND BREAK REPAIR	162	7.58e-01	-1.40e-02	9.61e-01
REACTOME TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS	43	7.58e-01	-2.71e-02	9.61e-01
REACTOME METABOLISM OF STEROIDS	150	7.59e-01	1.45e-02	9.61e-01
REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING	28	7.60e-01	3.34e-02	9.61e-01
REACTOME MET ACTIVATES RAS SIGNALING	11	7.61e-01	-5.31e-02	9.61e-01
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	122	7.61e-01	-1.59e-02	9.61e-01
REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	91	7.62e-01	-1.84e-02	9.61e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING	6	7.62e-01	-7.13e-02	9.61e-01
REACTOME SARS COV 2 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS	12	7.63e-01	5.04e-02	9.61e-01
REACTOME BILE ACID AND BILE SALT METABOLISM	45	7.63e-01	2.60e-02	9.61e-01
REACTOME GLUCOCORTICOID BIOSYNTHESIS	10	7.64e-01	5.48e-02	9.61e-01
REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	44	7.66e-01	-2.60e-02	9.62e-01
REACTOME UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION	19	7.67e-01	-3.93e-02	9.62e-01
REACTOME COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING	38	7.68e-01	2.77e-02	9.62e-01
REACTOME TBC RABGAPS	40	7.68e-01	-2.70e-02	9.62e-01
REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA	28	7.69e-01	3.21e-02	9.62e-01
REACTOME IRON UPTAKE AND TRANSPORT	56	7.69e-01	2.27e-02	9.62e-01
REACTOME ONCOGENE INDUCED SENESCENCE	35	7.70e-01	-2.86e-02	9.62e-01
REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	12	7.70e-01	4.87e-02	9.62e-01
REACTOME SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA PHE	6	7.72e-01	6.82e-02	9.62e-01
REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS	27	7.73e-01	-3.21e-02	9.62e-01
REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	122	7.74e-01	1.51e-02	9.62e-01
REACTOME PREDNISONE ADME	10	7.75e-01	5.22e-02	9.62e-01
REACTOME TRYPTOPHAN CATABOLISM	14	7.76e-01	-4.40e-02	9.62e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR4	14	7.77e-01	4.37e-02	9.62e-01
REACTOME CELL CYCLE MITOTIC	539	7.78e-01	7.11e-03	9.62e-01
REACTOME MYOCLONIC EPILEPSY OF LAFORA	9	7.80e-01	5.39e-02	9.62e-01
REACTOME INTERLEUKIN 12 FAMILY SIGNALING	53	7.80e-01	-2.22e-02	9.62e-01
REACTOME P38MAPK EVENTS	13	7.80e-01	4.47e-02	9.62e-01
REACTOME SARS COV 1 INFECTION	136	7.80e-01	1.38e-02	9.62e-01
REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH	62	7.82e-01	-2.04e-02	9.62e-01
REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	63	7.82e-01	2.02e-02	9.62e-01
REACTOME GAP JUNCTION DEGRADATION	12	7.83e-01	4.60e-02	9.62e-01
REACTOME ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS	10	7.84e-01	5.00e-02	9.62e-01
REACTOME SIGNALING BY THE B CELL RECEPTOR BCR	106	7.85e-01	1.53e-02	9.62e-01
REACTOME PLATELET SENSITIZATION BY LDL	17	7.85e-01	3.82e-02	9.62e-01
REACTOME RRNA PROCESSING IN THE MITOCHONDRION	9	7.85e-01	5.25e-02	9.62e-01
REACTOME FGFR2 ALTERNATIVE SPLICING	27	7.86e-01	3.03e-02	9.62e-01
REACTOME PI5P REGULATES TP53 ACETYLATION	9	7.86e-01	5.23e-02	9.62e-01
REACTOME REGULATION OF KIT SIGNALING	16	7.87e-01	-3.91e-02	9.62e-01
REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	30	7.87e-01	-2.85e-02	9.62e-01
REACTOME LATE SARS COV 2 INFECTION EVENTS	67	7.87e-01	-1.91e-02	9.62e-01
REACTOME REGULATION OF IFNG SIGNALING	14	7.87e-01	4.17e-02	9.62e-01
REACTOME TELOMERE C STRAND LAGGING STRAND SYNTHESIS	33	7.87e-01	2.71e-02	9.62e-01
REACTOME G2 M DNA REPLICATION CHECKPOINT	5	7.88e-01	6.95e-02	9.62e-01
REACTOME G2 PHASE	5	7.88e-01	-6.95e-02	9.62e-01
REACTOME S PHASE	159	7.88e-01	1.24e-02	9.62e-01
REACTOME TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7	12	7.88e-01	-4.48e-02	9.62e-01
REACTOME CELL CYCLE	666	7.88e-01	6.10e-03	9.62e-01
REACTOME VEGFR2 MEDIATED CELL PROLIFERATION	19	7.88e-01	-3.56e-02	9.62e-01
REACTOME GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION	14	7.88e-01	4.14e-02	9.62e-01
REACTOME COMPLEMENT CASCADE	54	7.89e-01	2.11e-02	9.62e-01
REACTOME PROTEIN METHYLATION	17	7.90e-01	-3.73e-02	9.63e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES	15	7.92e-01	3.92e-02	9.64e-01
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	55	7.93e-01	2.05e-02	9.64e-01
REACTOME GLYCOGEN SYNTHESIS	13	7.93e-01	4.19e-02	9.64e-01
REACTOME DEADENYLATION OF MRNA	25	7.94e-01	-3.02e-02	9.64e-01
REACTOME RHOBTB3 ATPASE CYCLE	8	7.94e-01	5.33e-02	9.64e-01
REACTOME DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE	30	7.96e-01	2.73e-02	9.65e-01
REACTOME SIGNALING BY WNT IN CANCER	32	7.96e-01	2.64e-02	9.65e-01
REACTOME METABOLISM OF NUCLEOTIDES	94	7.97e-01	-1.54e-02	9.65e-01
REACTOME LONG TERM POTENTIATION	22	7.97e-01	-3.16e-02	9.65e-01
REACTOME MITOTIC SPINDLE CHECKPOINT	109	7.98e-01	-1.42e-02	9.65e-01
REACTOME DSCAM INTERACTIONS	11	7.98e-01	-4.45e-02	9.65e-01
REACTOME TRANSCRIPTIONAL REGULATION BY MECP2	60	7.99e-01	1.90e-02	9.65e-01
REACTOME PI3K AKT ACTIVATION	9	8.01e-01	4.84e-02	9.65e-01
REACTOME PIWI INTERACTING RNA PIRNA BIOGENESIS	29	8.02e-01	2.70e-02	9.65e-01
REACTOME 2 LTR CIRCLE FORMATION	7	8.02e-01	5.47e-02	9.65e-01
REACTOME HYALURONAN METABOLISM	17	8.02e-01	-3.51e-02	9.65e-01
REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION	12	8.02e-01	-4.18e-02	9.65e-01
REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES	37	8.02e-01	-2.38e-02	9.65e-01
REACTOME G PROTEIN ACTIVATION	24	8.03e-01	-2.94e-02	9.66e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	27	8.04e-01	2.76e-02	9.66e-01
REACTOME PEXOPHAGY	11	8.05e-01	-4.30e-02	9.66e-01
REACTOME KERATAN SULFATE DEGRADATION	13	8.06e-01	-3.94e-02	9.66e-01
REACTOME MIRO GTPASE CYCLE	8	8.06e-01	5.00e-02	9.66e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS	6	8.08e-01	5.73e-02	9.66e-01
REACTOME MITOTIC PROMETAPHASE	194	8.09e-01	-1.01e-02	9.66e-01
REACTOME ALK MUTANTS BIND TKIS	12	8.09e-01	-4.03e-02	9.66e-01
REACTOME MITOTIC METAPHASE AND ANAPHASE	228	8.09e-01	-9.28e-03	9.66e-01
REACTOME SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER	15	8.09e-01	-3.60e-02	9.66e-01
REACTOME NONCANONICAL ACTIVATION OF NOTCH3	8	8.10e-01	-4.92e-02	9.66e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE	74	8.10e-01	1.62e-02	9.66e-01
REACTOME NUCLEAR SIGNALING BY ERBB4	32	8.11e-01	-2.44e-02	9.67e-01
REACTOME NGF STIMULATED TRANSCRIPTION	38	8.14e-01	-2.20e-02	9.69e-01
REACTOME DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS	14	8.14e-01	3.62e-02	9.69e-01
REACTOME HOMOLOGY DIRECTED REPAIR	132	8.15e-01	-1.18e-02	9.69e-01
REACTOME PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING	5	8.16e-01	6.00e-02	9.69e-01
REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	35	8.16e-01	-2.27e-02	9.69e-01
REACTOME CS DS DEGRADATION	12	8.17e-01	3.86e-02	9.69e-01
REACTOME HYALURONAN BIOSYNTHESIS AND EXPORT	5	8.17e-01	-5.96e-02	9.69e-01
REACTOME INTERLEUKIN 2 SIGNALING	11	8.20e-01	-3.97e-02	9.70e-01
REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX	36	8.20e-01	-2.19e-02	9.70e-01
REACTOME ERBB2 REGULATES CELL MOTILITY	15	8.21e-01	3.37e-02	9.70e-01
REACTOME PENTOSE PHOSPHATE PATHWAY	12	8.22e-01	-3.76e-02	9.70e-01
REACTOME SIGNALING BY INSULIN RECEPTOR	80	8.22e-01	1.45e-02	9.70e-01
REACTOME ACTIVATION OF C3 AND C5	6	8.23e-01	-5.28e-02	9.70e-01
REACTOME TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS	55	8.23e-01	-1.74e-02	9.70e-01
REACTOME MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION	15	8.24e-01	-3.32e-02	9.70e-01
REACTOME HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS	9	8.24e-01	-4.29e-02	9.70e-01
REACTOME INNATE IMMUNE SYSTEM	1002	8.27e-01	-4.09e-03	9.72e-01
REACTOME EFFECTS OF PIP2 HYDROLYSIS	26	8.27e-01	-2.48e-02	9.72e-01
REACTOME ACTIVATION OF RAS IN B CELLS	5	8.28e-01	5.62e-02	9.72e-01
REACTOME ACTIVATION OF NIMA KINASES NEK9 NEK6 NEK7	7	8.28e-01	-4.73e-02	9.72e-01
REACTOME FLT3 SIGNALING THROUGH SRC FAMILY KINASES	6	8.29e-01	5.09e-02	9.72e-01
REACTOME AMINO ACIDS REGULATE MTORC1	53	8.30e-01	-1.71e-02	9.72e-01
REACTOME NEGATIVE REGULATION OF ACTIVITY OF TFAP2 AP 2 FAMILY TRANSCRIPTION FACTORS	10	8.31e-01	3.90e-02	9.72e-01
REACTOME PHASE 2 PLATEAU PHASE	14	8.31e-01	3.29e-02	9.72e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS	5	8.32e-01	-5.48e-02	9.72e-01
REACTOME ASPARTATE AND ASPARAGINE METABOLISM	11	8.33e-01	3.68e-02	9.72e-01
REACTOME FORMATION OF PARAXIAL MESODERM	22	8.34e-01	2.58e-02	9.72e-01
REACTOME COENZYME A BIOSYNTHESIS	8	8.34e-01	-4.28e-02	9.72e-01
REACTOME REACTIONS SPECIFIC TO THE COMPLEX N GLYCAN SYNTHESIS PATHWAY	10	8.34e-01	3.83e-02	9.72e-01
REACTOME PARASITE INFECTION	57	8.34e-01	-1.60e-02	9.72e-01
REACTOME CARDIAC CONDUCTION	125	8.35e-01	1.08e-02	9.72e-01
REACTOME SIGNALING BY FLT3 FUSION PROTEINS	19	8.35e-01	2.77e-02	9.72e-01
REACTOME BASIGIN INTERACTIONS	24	8.36e-01	-2.44e-02	9.73e-01
REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	13	8.38e-01	-3.28e-02	9.73e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING	5	8.39e-01	5.25e-02	9.73e-01
REACTOME DOWNREGULATION OF ERBB4 SIGNALING	9	8.39e-01	3.91e-02	9.73e-01
REACTOME SUMO IS CONJUGATED TO E1 UBA2 SAE1	5	8.39e-01	-5.24e-02	9.73e-01
REACTOME ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING	23	8.39e-01	2.44e-02	9.73e-01
REACTOME SIGNALING BY NOTCH2	32	8.40e-01	2.06e-02	9.74e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING	5	8.42e-01	5.15e-02	9.75e-01
REACTOME PI METABOLISM	79	8.44e-01	-1.28e-02	9.76e-01
REACTOME SYNTHESIS OF UDP N ACETYL GLUCOSAMINE	7	8.44e-01	-4.28e-02	9.76e-01
REACTOME PURINE SALVAGE	12	8.45e-01	-3.27e-02	9.76e-01
REACTOME BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA	5	8.45e-01	-5.05e-02	9.76e-01
REACTOME TOLL LIKE RECEPTOR CASCADES	158	8.47e-01	-8.92e-03	9.76e-01
REACTOME CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY	25	8.47e-01	2.23e-02	9.76e-01
REACTOME DIGESTION AND ABSORPTION	22	8.47e-01	-2.37e-02	9.76e-01
REACTOME NUCLEOTIDE EXCISION REPAIR	107	8.49e-01	-1.07e-02	9.77e-01
REACTOME TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER	76	8.49e-01	1.26e-02	9.77e-01
REACTOME IRE1ALPHA ACTIVATES CHAPERONES	48	8.52e-01	-1.56e-02	9.79e-01
REACTOME ORGANIC ANION TRANSPORT	5	8.52e-01	4.82e-02	9.79e-01
REACTOME CREATION OF C4 AND C2 ACTIVATORS	14	8.54e-01	2.84e-02	9.79e-01
REACTOME DUAL INCISION IN TC NER	63	8.55e-01	1.34e-02	9.79e-01
REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	23	8.55e-01	2.21e-02	9.79e-01
REACTOME SYNTHESIS OF 12 EICOSATETRAENOIC ACID DERIVATIVES	7	8.55e-01	4.00e-02	9.79e-01
REACTOME RHOH GTPASE CYCLE	37	8.56e-01	1.72e-02	9.80e-01
REACTOME IKBA VARIANT LEADS TO EDA ID	6	8.56e-01	-4.28e-02	9.80e-01
REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION	19	8.60e-01	-2.34e-02	9.81e-01
REACTOME RRNA MODIFICATION IN THE MITOCHONDRION	6	8.60e-01	-4.15e-02	9.81e-01
REACTOME STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS	10	8.61e-01	-3.19e-02	9.81e-01
REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION	31	8.62e-01	1.80e-02	9.81e-01
REACTOME CILIUM ASSEMBLY	190	8.62e-01	-7.32e-03	9.81e-01
REACTOME ERBB2 ACTIVATES PTK6 SIGNALING	13	8.63e-01	2.76e-02	9.81e-01
REACTOME VIRAL MESSENGER RNA SYNTHESIS	44	8.64e-01	1.50e-02	9.81e-01
REACTOME PROGRAMMED CELL DEATH	204	8.64e-01	6.96e-03	9.81e-01
REACTOME DEFECTIVE F9 ACTIVATION	5	8.66e-01	4.37e-02	9.81e-01
REACTOME EPITHELIAL MESENCHYMAL TRANSITION EMT DURING GASTRULATION	7	8.67e-01	3.65e-02	9.81e-01
REACTOME SHC1 EVENTS IN ERBB2 SIGNALING	22	8.68e-01	2.04e-02	9.81e-01
REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	54	8.68e-01	-1.31e-02	9.81e-01
REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	37	8.68e-01	-1.57e-02	9.81e-01
REACTOME NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS	25	8.69e-01	1.91e-02	9.81e-01
REACTOME ABACAVIR ADME	9	8.70e-01	-3.16e-02	9.81e-01
REACTOME SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA	52	8.70e-01	-1.32e-02	9.81e-01
REACTOME ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS	20	8.70e-01	2.12e-02	9.81e-01
REACTOME EXTRA NUCLEAR ESTROGEN SIGNALING	74	8.72e-01	-1.08e-02	9.81e-01
REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS	68	8.72e-01	-1.13e-02	9.81e-01
REACTOME MRNA SPLICING MINOR PATHWAY	49	8.72e-01	-1.33e-02	9.81e-01
REACTOME DEFECTIVE GALNT3 CAUSES HFTC	16	8.72e-01	-2.32e-02	9.81e-01
REACTOME REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE	81	8.72e-01	1.03e-02	9.81e-01
REACTOME INDUCTION OF CELL CELL FUSION	12	8.73e-01	-2.67e-02	9.81e-01
REACTOME SUMOYLATION OF TRANSCRIPTION FACTORS	20	8.74e-01	-2.04e-02	9.81e-01
REACTOME INFLAMMASOMES	21	8.75e-01	1.99e-02	9.81e-01
REACTOME SIGNALING BY PTK6	54	8.75e-01	-1.24e-02	9.81e-01
REACTOME MULTIFUNCTIONAL ANION EXCHANGERS	9	8.77e-01	2.99e-02	9.81e-01
REACTOME REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR	11	8.77e-01	-2.69e-02	9.81e-01
REACTOME INTEGRATION OF PROVIRUS	9	8.80e-01	2.91e-02	9.81e-01
REACTOME CREB PHOSPHORYLATION	6	8.81e-01	-3.54e-02	9.81e-01
REACTOME HYALURONAN UPTAKE AND DEGRADATION	12	8.81e-01	-2.49e-02	9.81e-01
REACTOME REGULATION OF TP53 ACTIVITY	156	8.81e-01	6.93e-03	9.81e-01
REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	14	8.83e-01	-2.27e-02	9.81e-01
REACTOME ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS	24	8.83e-01	-1.74e-02	9.81e-01
REACTOME RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION	6	8.83e-01	3.47e-02	9.81e-01
REACTOME SUMO IS PROTEOLYTICALLY PROCESSED	6	8.84e-01	3.44e-02	9.81e-01
REACTOME TYSND1 CLEAVES PEROXISOMAL PROTEINS	7	8.86e-01	-3.12e-02	9.81e-01
REACTOME PHOSPHORYLATION OF EMI1	6	8.88e-01	-3.33e-02	9.81e-01
REACTOME GLYCEROPHOSPHOLIPID CATABOLISM	7	8.88e-01	-3.07e-02	9.81e-01
REACTOME SENSORY PROCESSING OF SOUND	72	8.89e-01	9.55e-03	9.81e-01
REACTOME COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES	65	8.89e-01	1.00e-02	9.81e-01
REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES	29	8.90e-01	-1.49e-02	9.81e-01
REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	26	8.91e-01	1.56e-02	9.81e-01
REACTOME INTRA GOLGI TRAFFIC	43	8.92e-01	-1.20e-02	9.81e-01
REACTOME GROWTH HORMONE RECEPTOR SIGNALING	24	8.92e-01	-1.60e-02	9.81e-01
REACTOME REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS	11	8.92e-01	2.36e-02	9.81e-01
REACTOME SIGNALING BY CSF3 G CSF	30	8.93e-01	1.42e-02	9.81e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH METHYLATION	19	8.94e-01	-1.77e-02	9.81e-01
REACTOME PROPIONYL COA CATABOLISM	5	8.94e-01	3.45e-02	9.81e-01
REACTOME DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA	77	8.95e-01	8.69e-03	9.81e-01
REACTOME POLB DEPENDENT LONG PATCH BASE EXCISION REPAIR	8	8.96e-01	-2.68e-02	9.81e-01
REACTOME RHOC GTPASE CYCLE	71	8.96e-01	-8.98e-03	9.81e-01
REACTOME RHOBTB2 GTPASE CYCLE	22	8.96e-01	1.60e-02	9.81e-01
REACTOME SARS COV INFECTIONS	392	8.97e-01	3.82e-03	9.81e-01
REACTOME REGULATED PROTEOLYSIS OF P75NTR	11	8.97e-01	2.26e-02	9.81e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS	14	8.97e-01	-2.00e-02	9.81e-01
REACTOME STAT3 NUCLEAR EVENTS DOWNSTREAM OF ALK SIGNALING	9	8.97e-01	-2.48e-02	9.81e-01
REACTOME TRANSPORT OF NUCLEOTIDE SUGARS	8	8.99e-01	2.60e-02	9.81e-01
REACTOME PROLONGED ERK ACTIVATION EVENTS	14	8.99e-01	1.97e-02	9.81e-01
REACTOME O LINKED GLYCOSYLATION	109	8.99e-01	7.04e-03	9.81e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	14	8.99e-01	-1.96e-02	9.81e-01
REACTOME FCERI MEDIATED MAPK ACTIVATION	32	8.99e-01	1.29e-02	9.81e-01
REACTOME IRF3 MEDIATED INDUCTION OF TYPE I IFN	13	8.99e-01	2.03e-02	9.81e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	11	9.01e-01	-2.17e-02	9.81e-01
REACTOME DEX H BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION	7	9.02e-01	2.70e-02	9.81e-01
REACTOME LGI ADAM INTERACTIONS	14	9.02e-01	-1.90e-02	9.81e-01
REACTOME SUMOYLATION OF UBIQUITINYLATION PROTEINS	39	9.02e-01	-1.14e-02	9.81e-01
REACTOME NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS	22	9.02e-01	1.51e-02	9.81e-01
REACTOME BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA	6	9.03e-01	2.88e-02	9.81e-01
REACTOME TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS	52	9.03e-01	-9.78e-03	9.81e-01
REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	11	9.04e-01	2.11e-02	9.81e-01
REACTOME SARS COV 2 MODULATES AUTOPHAGY	11	9.05e-01	-2.08e-02	9.81e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1	20	9.05e-01	1.54e-02	9.81e-01
REACTOME ALPHA OXIDATION OF PHYTANATE	6	9.06e-01	-2.80e-02	9.81e-01
REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	19	9.06e-01	1.57e-02	9.81e-01
REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES	78	9.06e-01	-7.76e-03	9.81e-01
REACTOME FGFR3 LIGAND BINDING AND ACTIVATION	12	9.07e-01	1.96e-02	9.81e-01
REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	13	9.07e-01	-1.88e-02	9.81e-01
REACTOME INACTIVATION OF CSF3 G CSF SIGNALING	25	9.07e-01	-1.35e-02	9.81e-01
REACTOME OPSINS	7	9.07e-01	2.54e-02	9.81e-01
REACTOME SIGNALING BY SCF KIT	42	9.08e-01	1.03e-02	9.81e-01
REACTOME SCAVENGING BY CLASS F RECEPTORS	6	9.09e-01	-2.71e-02	9.81e-01
REACTOME PREGNENOLONE BIOSYNTHESIS	12	9.09e-01	1.91e-02	9.81e-01
REACTOME CITRIC ACID CYCLE TCA CYCLE	21	9.10e-01	-1.43e-02	9.81e-01
REACTOME BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA	5	9.10e-01	-2.93e-02	9.81e-01
REACTOME REGULATION OF BETA CELL DEVELOPMENT	41	9.10e-01	-1.02e-02	9.81e-01
REACTOME RECYCLING OF BILE ACIDS AND SALTS	18	9.10e-01	-1.54e-02	9.81e-01
REACTOME INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	28	9.11e-01	1.23e-02	9.81e-01
REACTOME CONJUGATION OF BENZOATE WITH GLYCINE	6	9.11e-01	-2.65e-02	9.81e-01
REACTOME KILLING MECHANISMS	11	9.13e-01	-1.89e-02	9.84e-01
REACTOME SMALL INTERFERING RNA SIRNA BIOGENESIS	9	9.15e-01	2.05e-02	9.85e-01
REACTOME SUPPRESSION OF APOPTOSIS	7	9.16e-01	2.30e-02	9.85e-01
REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	20	9.16e-01	-1.36e-02	9.85e-01
REACTOME RND3 GTPASE CYCLE	41	9.17e-01	9.35e-03	9.85e-01
REACTOME RELEASE OF HH NP FROM THE SECRETING CELL	8	9.19e-01	-2.08e-02	9.86e-01
REACTOME MET RECEPTOR RECYCLING	10	9.21e-01	1.82e-02	9.87e-01
REACTOME MYD88 INDEPENDENT TLR4 CASCADE	103	9.21e-01	-5.65e-03	9.87e-01
REACTOME OTHER INTERLEUKIN SIGNALING	24	9.22e-01	-1.15e-02	9.87e-01
REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING	45	9.23e-01	8.34e-03	9.87e-01
REACTOME SNRNP ASSEMBLY	53	9.23e-01	7.65e-03	9.87e-01
REACTOME PKMTS METHYLATE HISTONE LYSINES	64	9.24e-01	6.93e-03	9.87e-01
REACTOME RND2 GTPASE CYCLE	42	9.24e-01	8.54e-03	9.87e-01
REACTOME INTERLEUKIN 23 SIGNALING	9	9.25e-01	-1.81e-02	9.87e-01
REACTOME TYPE I HEMIDESMOSOME ASSEMBLY	11	9.25e-01	1.63e-02	9.87e-01
REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS	14	9.26e-01	-1.44e-02	9.87e-01
REACTOME DOWNREGULATION OF ERBB2 SIGNALING	29	9.26e-01	9.97e-03	9.87e-01
REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	18	9.27e-01	-1.26e-02	9.87e-01
REACTOME TIE2 SIGNALING	18	9.28e-01	1.23e-02	9.87e-01
REACTOME FREE FATTY ACIDS REGULATE INSULIN SECRETION	10	9.29e-01	1.63e-02	9.87e-01
REACTOME GPVI MEDIATED ACTIVATION CASCADE	35	9.30e-01	8.57e-03	9.87e-01
REACTOME METABOLISM OF PORPHYRINS	26	9.30e-01	9.93e-03	9.87e-01
REACTOME REGULATED NECROSIS	57	9.30e-01	-6.70e-03	9.87e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS	12	9.31e-01	-1.45e-02	9.87e-01
REACTOME CELLULAR RESPONSE TO HEAT STRESS	99	9.32e-01	-4.98e-03	9.88e-01
REACTOME ACTIVATION OF RAC1	12	9.32e-01	1.41e-02	9.88e-01
REACTOME RHO GTPASES ACTIVATE WASPS AND WAVES	34	9.33e-01	-8.33e-03	9.88e-01
REACTOME TOLL LIKE RECEPTOR 9 TLR9 CASCADE	100	9.33e-01	-4.84e-03	9.88e-01
REACTOME PROCESSING AND ACTIVATION OF SUMO	10	9.35e-01	1.50e-02	9.88e-01
REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES	27	9.35e-01	9.11e-03	9.88e-01
REACTOME DEFECTIVE B4GALT1 CAUSES B4GALT1 CDG CDG 2D	8	9.36e-01	-1.65e-02	9.88e-01
REACTOME OAS ANTIVIRAL RESPONSE	8	9.37e-01	-1.62e-02	9.88e-01
REACTOME NUCLEAR PORE COMPLEX NPC DISASSEMBLY	36	9.37e-01	-7.59e-03	9.88e-01
REACTOME GLYCOGEN STORAGE DISEASES	15	9.38e-01	-1.16e-02	9.88e-01
REACTOME CALCINEURIN ACTIVATES NFAT	9	9.39e-01	-1.47e-02	9.88e-01
REACTOME NTRK2 ACTIVATES RAC1	5	9.39e-01	1.97e-02	9.88e-01
REACTOME MUSCARINIC ACETYLCHOLINE RECEPTORS	5	9.40e-01	-1.95e-02	9.88e-01
REACTOME SYNDECAN INTERACTIONS	26	9.40e-01	8.53e-03	9.88e-01
REACTOME CHYLOMICRON CLEARANCE	5	9.40e-01	-1.93e-02	9.88e-01
REACTOME MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS	13	9.44e-01	1.13e-02	9.90e-01
REACTOME DNA REPAIR	321	9.44e-01	2.29e-03	9.90e-01
REACTOME GABA RECEPTOR ACTIVATION	57	9.46e-01	-5.20e-03	9.91e-01
REACTOME DNA DAMAGE BYPASS	47	9.46e-01	5.71e-03	9.91e-01
REACTOME CROSS PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS PHAGOSOMES	6	9.48e-01	-1.54e-02	9.92e-01
REACTOME CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION	24	9.48e-01	7.63e-03	9.92e-01
REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	15	9.50e-01	9.38e-03	9.92e-01
REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	16	9.50e-01	-9.08e-03	9.92e-01
REACTOME FCERI MEDIATED CA 2 MOBILIZATION	30	9.50e-01	6.59e-03	9.92e-01
REACTOME MET ACTIVATES PTPN11	5	9.51e-01	-1.60e-02	9.92e-01
REACTOME ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN	13	9.51e-01	9.87e-03	9.92e-01
REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA	11	9.52e-01	1.05e-02	9.92e-01
REACTOME ENDOGENOUS STEROLS	26	9.53e-01	-6.69e-03	9.93e-01
REACTOME HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR IN THE PRESENCE OF LIGAND	55	9.54e-01	-4.54e-03	9.93e-01
REACTOME INTERLEUKIN 9 SIGNALING	7	9.56e-01	1.21e-02	9.93e-01
REACTOME RHOF GTPASE CYCLE	40	9.56e-01	4.99e-03	9.93e-01
REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS	5	9.57e-01	-1.40e-02	9.93e-01
REACTOME REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA	15	9.57e-01	7.99e-03	9.93e-01
REACTOME NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS	11	9.58e-01	-9.23e-03	9.93e-01
REACTOME NFE2L2 REGULATING ANTI OXIDANT DETOXIFICATION ENZYMES	17	9.59e-01	7.21e-03	9.93e-01
REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	13	9.59e-01	8.23e-03	9.93e-01
REACTOME INTERLEUKIN 10 SIGNALING	43	9.61e-01	-4.36e-03	9.93e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH PI3K	6	9.61e-01	1.15e-02	9.93e-01
REACTOME PYRIMIDINE CATABOLISM	12	9.61e-01	-8.08e-03	9.93e-01
REACTOME NECTIN NECL TRANS HETERODIMERIZATION	7	9.62e-01	1.03e-02	9.93e-01
REACTOME SIGNALING BY LEPTIN	11	9.63e-01	8.02e-03	9.93e-01
REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	89	9.63e-01	2.82e-03	9.93e-01
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM	688	9.64e-01	-9.96e-04	9.93e-01
REACTOME DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15	8	9.65e-01	9.08e-03	9.93e-01
REACTOME RHOT1 GTPASE CYCLE	5	9.65e-01	-1.14e-02	9.93e-01
REACTOME DISEASES OF DNA REPAIR	51	9.65e-01	-3.55e-03	9.93e-01
REACTOME CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2	11	9.65e-01	7.56e-03	9.93e-01
REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	11	9.66e-01	-7.39e-03	9.93e-01
REACTOME INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE	20	9.66e-01	-5.43e-03	9.93e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FYN	7	9.67e-01	-9.01e-03	9.93e-01
REACTOME NGF INDEPENDANT TRKA ACTIVATION	5	9.67e-01	-1.06e-02	9.93e-01
REACTOME TRIGLYCERIDE CATABOLISM	23	9.69e-01	-4.72e-03	9.93e-01
REACTOME ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION	16	9.69e-01	5.62e-03	9.93e-01
REACTOME SPRY REGULATION OF FGF SIGNALING	16	9.70e-01	-5.39e-03	9.93e-01
REACTOME TLR3 MEDIATED TICAM1 DEPENDENT PROGRAMMED CELL DEATH	6	9.71e-01	8.55e-03	9.93e-01
REACTOME GLUCONEOGENESIS	33	9.71e-01	-3.62e-03	9.93e-01
REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE	19	9.72e-01	-4.66e-03	9.93e-01
REACTOME SIGNALING BY NOTCH1 T 7 9 NOTCH1 M1580 K2555 TRANSLOCATION MUTANT	7	9.72e-01	7.66e-03	9.93e-01
REACTOME CARNITINE METABOLISM	13	9.73e-01	-5.50e-03	9.93e-01
REACTOME RIP MEDIATED NFKB ACTIVATION VIA ZBP1	16	9.73e-01	4.94e-03	9.93e-01
REACTOME INTERLEUKIN 21 SIGNALING	9	9.74e-01	6.29e-03	9.93e-01
REACTOME INTERLEUKIN 6 SIGNALING	11	9.74e-01	-5.68e-03	9.93e-01
REACTOME SIGNALING BY RECEPTOR TYROSINE KINASES	507	9.74e-01	8.38e-04	9.93e-01
REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	51	9.76e-01	-2.46e-03	9.94e-01
REACTOME DERMATAN SULFATE BIOSYNTHESIS	10	9.77e-01	-5.28e-03	9.94e-01
REACTOME AGGREPHAGY	42	9.78e-01	2.50e-03	9.94e-01
REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK	17	9.78e-01	3.85e-03	9.94e-01
REACTOME PHASE 4 RESTING MEMBRANE POTENTIAL	19	9.81e-01	3.07e-03	9.97e-01
REACTOME NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	11	9.82e-01	-3.98e-03	9.97e-01
REACTOME ATTENUATION PHASE	27	9.83e-01	2.34e-03	9.97e-01
REACTOME ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA	15	9.83e-01	3.14e-03	9.97e-01
REACTOME RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION	6	9.84e-01	-4.71e-03	9.97e-01
REACTOME RAS SIGNALING DOWNSTREAM OF NF1 LOSS OF FUNCTION VARIANTS	7	9.84e-01	4.31e-03	9.97e-01
REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	28	9.85e-01	2.12e-03	9.97e-01
REACTOME L1CAM INTERACTIONS	112	9.86e-01	-9.77e-04	9.97e-01
REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	36	9.86e-01	1.64e-03	9.97e-01
REACTOME EXTRACELLULAR MATRIX ORGANIZATION	291	9.88e-01	5.14e-04	9.97e-01
REACTOME VITAMINS	6	9.88e-01	-3.55e-03	9.97e-01
REACTOME XENOBIOTICS	22	9.89e-01	1.72e-03	9.97e-01
REACTOME DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B	7	9.89e-01	3.00e-03	9.97e-01
REACTOME UNWINDING OF DNA	12	9.89e-01	-2.21e-03	9.97e-01
REACTOME REGULATION OF NPAS4 GENE TRANSCRIPTION	5	9.90e-01	3.36e-03	9.97e-01
REACTOME SUMOYLATION OF IMMUNE RESPONSE PROTEINS	10	9.91e-01	-2.09e-03	9.97e-01
REACTOME PHYSIOLOGICAL FACTORS	14	9.91e-01	1.73e-03	9.97e-01
REACTOME RUNX3 REGULATES P14 ARF	10	9.92e-01	-1.85e-03	9.97e-01
REACTOME BIOSYNTHESIS OF MARESINS	8	9.92e-01	-1.92e-03	9.97e-01
REACTOME TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY	16	9.93e-01	1.24e-03	9.97e-01
REACTOME DISINHIBITION OF SNARE FORMATION	5	9.94e-01	-2.09e-03	9.97e-01
REACTOME SIGNALING BY ALK IN CANCER	53	9.94e-01	6.17e-04	9.97e-01
REACTOME RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR	19	9.95e-01	8.33e-04	9.97e-01
REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS	33	9.96e-01	4.99e-04	9.97e-01
REACTOME PLASMA LIPOPROTEIN REMODELING	33	9.96e-01	4.85e-04	9.97e-01
REACTOME MRNA CAPPING	28	9.99e-01	-9.75e-05	1.00e+00
REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX	39	1.00e+00	-3.27e-05	1.00e+00

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Detailed Gene set reports

REACTOME_OLFACTORY_SIGNALING_PATHWAY

REACTOME_OLFACTORY_SIGNALING_PATHWAY

	628
set	REACTOME_OLFACTORY_SIGNALING_PATHWAY
setSize	348
pANOVA	2.57e-14
s.dist	0.238
p.adjustANOVA	4.23e-11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
OR8B12	11986
OR6Q1	11962
OR2T3	11955
OR2AT4	11952
OR52E2	11937
OR51F1	11931
OR2Y1	11905
OR4A47	11899
OR6C6	11894
OR10J3	11872
OR8H3	11858
OR51T1	11857
OR5J2	11831
OR1S2	11822
OR52K2	11799
OR52R1	11797
OR8B4	11770
OR5M1	11749
OR10A4	11748
OR7G1	11747

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
OR8B12	11986.0
OR6Q1	11962.0
OR2T3	11955.0
OR2AT4	11952.0
OR52E2	11937.0
OR51F1	11931.0
OR2Y1	11905.0
OR4A47	11899.0
OR6C6	11894.0
OR10J3	11872.0
OR8H3	11858.0
OR51T1	11857.0
OR5J2	11831.0
OR1S2	11822.0
OR52K2	11799.0
OR52R1	11797.0
OR8B4	11770.0
OR5M1	11749.0
OR10A4	11748.0
OR7G1	11747.0
OR6P1	11734.0
OR5B17	11704.0
OR2G2	11689.0
OR10H5	11674.0
OR56B4	11672.0
OR5M11	11644.0
OR11L1	11636.0
OR1C1	11631.0
OR1I1	11628.0
OR2AG1	11605.0
OR5D18	11596.0
OR56A5	11589.0
OR10V1	11581.0
OR5P3	11576.0
OR51V1	11569.0
OR6V1	11554.0
OR51L1	11548.0
OR51Q1	11546.0
OR2A5	11531.0
OR4A16	11527.0
OR2D2	11522.0
OR9K2	11502.0
OR2L3	11484.0
OR5T1	11469.0
OR5D14	11456.0
OR51B4	11454.0
OR10J1	11431.0
OR51A2	11426.0
OR51B6	11418.0
OR4K15	11357.0
OR1J1	11356.0
OR5M8	11345.0
OR3A1	11336.0
OR6C74	11236.0
OR9A2	11227.0
OR13C4	11218.0
OR10G9	11211.0
OR10J5	11205.0
OR14I1	11202.0
OR10P1	11176.0
OR52N2	11167.0
OR51I1	11122.0
OR2F2	11121.0
OR2T12	11080.0
OR2A2	11063.0
OR4F6	11054.0
OR2J2	11024.0
OR2S2	10993.0
OR6A2	10987.0
OR5AU1	10984.0
OR4D6	10973.0
OR4D5	10961.0
OR10C1	10957.0
OR8G5	10944.0
OR10Z1	10939.0
OR2D3	10911.0
OR51M1	10900.0
OR2A14	10885.0
OR5AK2	10866.0
OR6C2	10860.0
OR4C15	10819.0
OR6T1	10812.0
OR4D2	10785.0
OR52E4	10774.0
OR9Q2	10753.0
OR4M1	10703.0
OR3A2	10685.0
OR10AG1	10670.0
OR5C1	10610.0
OR11A1	10591.0
OR52M1	10576.0
OR7C1	10574.0
OR4X2	10568.0
OR51G1	10499.0
OR9Q1	10414.0
OR8B2	10310.0
OR51E1	10213.0
OR8D1	10201.0
OR51A7	10087.0
OR51B2	10058.0
OR5B2	10002.0
OR4D11	9955.0
OR1F1	9938.0
OR6X1	9883.0
OR6C65	9873.0
OR8U8	9872.0
OR2M7	9803.0
OR2T6	9797.0
CNGA4	9795.0
OR4C6	9759.0
OR8B8	9734.0
OR7G2	9655.0
OR2L8	9570.0
OR9G4	9550.0
OR6F1	9389.0
OR4A15	9351.0
OR6C70	9337.0
OR6B3	9329.0
OR5AN1	9269.0
OR1E2	8974.0
OR2B6	8963.5
OR4C3	8807.0
OR10A3	8755.0
OR2W3	8740.0
OR5D16	8724.0
OR6N1	8715.0
OR6M1	8646.0
OR51F2	8638.0
OR4K17	8569.0
OR9I1	8514.0
OR51B5	8504.0
OR2AK2	8448.0
OR7G3	8423.0
LHX2	8400.0
OR2M5	8340.0
OR10Q1	8330.0
OR56A3	8318.0
OR12D3	8219.0
OR4K14	8023.0
OR51S1	8008.0
OR5AC2	7987.0
OR8S1	7928.0
OR4D1	7814.0
OR10A7	7575.0
OR5AR1	7513.0
OR52B6	7384.0
OR1J2	7318.0
OR4C46	7274.0
OR2L13	7087.0
OR1L4	6920.0
OR5W2	6911.0
OR2B11	6892.0
OR2Z1	6834.0
OR5L2	6757.0
OR5B3	6741.0
OR4K5	6731.0
OR4D9	6697.0
OR10H4	6683.0
OR52A1	6682.0
OR10A6	6594.0
OR4N2	6531.0
OR2T27	6431.0
OR5H1	6429.0
OR10X1	6340.0
OR4F15	6311.0
OR2L5	6264.0
OR2C3	6220.0
OR5AP2	6150.0
OR2M2	6000.0
OR5H6	5860.0
OR8K1	5711.0
OR6K6	5625.0
OR5K1	5310.0
OR5AS1	5269.0
OR10K1	5201.0
LDB1	5174.0
OR2H1	5153.0
OR1N2	5092.0
OR5P2	5069.0
OR13A1	5030.0
OR7A5	4872.0
OR4C16	4840.0
OR10W1	4830.0
OR2G3	4811.0
OR4K1	4690.0
OR13C2	4416.0
OR51D1	4408.0
OR1B1	4339.0
OR52A5	4318.0
OR51I2	3971.0
OR2L2	3802.0
OR1L3	3726.0
OR2V1	3706.0
OR2F1	3673.0
OR6B1	3654.0
OR4C12	3648.0
OR2AG2	3614.0
OR8A1	3510.0
OR6S1	3473.0
OR5A2	3451.0
OR8G1	3358.0
OR1Q1	3239.0
OR6C76	3220.0
OR8H1	3193.0
OR52E8	3121.0
OR6C68	3116.0
OR5A1	2734.0
OR12D2	2692.0
GNG13	2486.0
ANO2	2410.0
OR4N5	2326.0
OR7A10	2164.0
OR8U1	2086.0
EBF1	2066.0
OR14C36	1995.0
OR13C3	1751.0
OR10T2	1736.0
OR5I1	1696.0
OR52J3	1497.0
GNAL	1453.0
OR4S1	1125.0
OR1E1	1062.0
OR1G1	978.0
OR9A4	977.0
OR5M3	886.0
OR10A2	813.0
OR4B1	711.0
OR10H1	706.0
OR6B2	576.0
OR2W1	569.0
OR1L8	385.0
OR2T4	-54.0
OR2M4	-377.0
OR5H15	-384.0
OR52I2	-738.0
OR11G2	-745.0
OR8J3	-764.0
OR13C9	-812.0
OR13G1	-871.0
OR7D2	-918.0
OR4K2	-1056.0
OR10G7	-1081.0
OR2AP1	-1100.0
OR5M10	-1133.0
OR2B3	-1375.0
OR2G6	-1385.0
OR1S1	-1410.0
GNB1	-1458.0
OR2V2	-1680.0
OR52D1	-1805.0
OR2T33	-1895.0
OR8K3	-1924.0
OR52E6	-2001.0
OR4D10	-2076.0
OR2C1	-2149.0
OR8K5	-2182.0
OR5F1	-2231.0
OR51E2	-2378.0
OR9G1	-2412.5
OR9G9	-2412.5
OR13C8	-2520.0
OR6C75	-2570.0
REEP1	-2695.0
OR51G2	-2761.0
OR1A2	-2800.0
OR1M1	-2828.0
OR14A16	-2997.0
OR10G4	-3098.0
OR5T3	-3200.0
OR1D2	-3425.0
OR52N1	-3669.0
OR5V1	-3760.0
OR8D4	-3965.0
OR4X1	-3976.0
OR10S1	-4005.0
OR6C4	-4168.0
CNGB1	-4197.0
OR7D4	-4384.0
OR6Y1	-4392.0
OR2T8	-4428.0
OR3A3	-4774.0
OR6C1	-5161.0
OR52I1	-5227.0
OR4A5	-5289.0
OR5D13	-5441.0
OR6C3	-5525.0
OR2M3	-5586.0
OR7A17	-5618.0
OR4E2	-5646.0
OR52H1	-5674.0
OR2AE1	-5782.0
OR13D1	-6138.0
OR5T2	-6359.0
OR8J1	-6369.0
OR6K2	-6409.0
OR5B21	-6410.0
ADCY3	-6497.0
OR8U3	-6630.0
OR10K2	-6641.0
OR5L1	-6765.0
RTP2	-6844.0
OR11H6	-6888.0
OR52W1	-6907.0
OR1N1	-6929.0
OR56A4	-7065.0
OR14J1	-7125.0
OR5K2	-7389.0
OR10AD1	-7486.0
OR52K1	-7514.0
OR56B1	-7726.0
OR10G3	-7749.0
OR8D2	-7765.0
OR1A1	-7797.0
OR10H2	-7840.5
OR10H3	-7844.0
OR7E24	-7862.0
RTP1	-7945.0
OR13F1	-7974.0
OR2T1	-8003.0
OR6K3	-8031.0
OR52B2	-8044.0
OR7C2	-8070.0
OR10A5	-8257.0
OR13J1	-8482.0
OR4C45	-8574.0
OR2H2	-8620.0
OR1L6	-8778.0
OR1J4	-8844.0
OR1L1	-8845.0
OR5B12	-8962.0
OR10G2	-9015.0
OR2B2	-9054.0
OR4L1	-9089.0
OR2T11	-9111.0
OR5H2	-9170.0
OR11H4	-9241.0
OR5K4	-9282.0
OR10G8	-9429.0
OR2K2	-9474.0
OR5M9	-9506.0
OR4K13	-9508.0
OR2A12	-9533.0
OR1K1	-9570.0
OR6N2	-9635.0
OR56A1	-9668.0
OR5K3	-9913.0
OR52L1	-9930.0
OR8I2	-9969.0

---

REACTOME_SENSORY_PERCEPTION

REACTOME_SENSORY_PERCEPTION

	1581
set	REACTOME_SENSORY_PERCEPTION
setSize	555
pANOVA	6.37e-09
s.dist	0.144
p.adjustANOVA	5.23e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
OR8B12	11986
OR6Q1	11962
OR2T3	11955
OR2AT4	11952
OR52E2	11937
OR51F1	11931
OR2Y1	11905
OR4A47	11899
OR6C6	11894
OR10J3	11872
OR8H3	11858
OR51T1	11857
APOC2	11840
OR5J2	11831
OR1S2	11822
OR52K2	11799
OR52R1	11797
OR8B4	11770
OR5M1	11749
OR10A4	11748

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
OR8B12	11986.0
OR6Q1	11962.0
OR2T3	11955.0
OR2AT4	11952.0
OR52E2	11937.0
OR51F1	11931.0
OR2Y1	11905.0
OR4A47	11899.0
OR6C6	11894.0
OR10J3	11872.0
OR8H3	11858.0
OR51T1	11857.0
APOC2	11840.0
OR5J2	11831.0
OR1S2	11822.0
OR52K2	11799.0
OR52R1	11797.0
OR8B4	11770.0
OR5M1	11749.0
OR10A4	11748.0
OR7G1	11747.0
OR6P1	11734.0
OR5B17	11704.0
OR2G2	11689.0
OR10H5	11674.0
OR56B4	11672.0
OR5M11	11644.0
OR11L1	11636.0
OR1C1	11631.0
OR1I1	11628.0
OR2AG1	11605.0
OR5D18	11596.0
OR56A5	11589.0
OR10V1	11581.0
OR5P3	11576.0
OR51V1	11569.0
OR6V1	11554.0
OR51L1	11548.0
OR51Q1	11546.0
OR2A5	11531.0
OR4A16	11527.0
RDH16	11526.0
OR2D2	11522.0
OR9K2	11502.0
SCN3A	11501.0
OR2L3	11484.0
OR5T1	11469.0
OR5D14	11456.0
OR51B4	11454.0
OR10J1	11431.0
OR51A2	11426.0
OR51B6	11418.0
OR4K15	11357.0
OR1J1	11356.0
OR5M8	11345.0
OR3A1	11336.0
OR6C74	11236.0
OR9A2	11227.0
OR13C4	11218.0
OR10G9	11211.0
OR10J5	11205.0
OR14I1	11202.0
TAS2R40	11177.0
OR10P1	11176.0
OR52N2	11167.0
OR51I1	11122.0
OR2F2	11121.0
OR2T12	11080.0
OR2A2	11063.0
OR4F6	11054.0
OR2J2	11024.0
OR2S2	10993.0
OR6A2	10987.0
OR5AU1	10984.0
OR4D6	10973.0
OR4D5	10961.0
OR10C1	10957.0
OR8G5	10944.0
OR10Z1	10939.0
OR2D3	10911.0
XIRP2	10904.0
OR51M1	10900.0
OR2A14	10885.0
OR5AK2	10866.0
OR6C2	10860.0
OR4C15	10819.0
OR6T1	10812.0
OR4D2	10785.0
OR52E4	10774.0
TAS2R31	10761.0
OR9Q2	10753.0
RDH5	10750.0
OR4M1	10703.0
OR3A2	10685.0
OR10AG1	10670.0
TAS2R38	10634.0
OR5C1	10610.0
OR11A1	10591.0
OR52M1	10576.0
OR7C1	10574.0
OR4X2	10568.0
OR51G1	10499.0
OR9Q1	10414.0
OR8B2	10310.0
OR51E1	10213.0
OR8D1	10201.0
TAS2R13	10097.0
OR51A7	10087.0
OR51B2	10058.0
OR5B2	10002.0
APOA4	9996.0
PCLO	9983.0
OR4D11	9955.0
OR1F1	9938.0
RBP1	9924.0
OR6X1	9883.0
OR6C65	9873.0
OR8U8	9872.0
GRXCR2	9823.0
OR2M7	9803.0
OR2T6	9797.0
CNGA4	9795.0
OR4C6	9759.0
SDR9C7	9758.0
OR8B8	9734.0
SLC26A5	9711.0
OR7G2	9655.0
AKR1B10	9625.0
AKR1C4	9594.0
OR2L8	9570.0
OR9G4	9550.0
RCVRN	9519.0
BSN	9482.0
OR6F1	9389.0
OR4A15	9351.0
OR6C70	9337.0
OR6B3	9329.0
OR5AN1	9269.0
RDH8	9247.0
LRAT	9022.0
OR1E2	8974.0
OR2B6	8963.5
PNLIP	8907.0
GRM1	8825.0
OR4C3	8807.0
SCN9A	8802.0
OR10A3	8755.0
RHO	8741.0
OR2W3	8740.0
OR5D16	8724.0
OR6N1	8715.0
GUCA1C	8713.0
OR6M1	8646.0
OR51F2	8638.0
CACNB2	8636.0
GRXCR1	8635.0
OR4K17	8569.0
HSD17B6	8540.0
OR9I1	8514.0
OR51B5	8504.0
OR2AK2	8448.0
EPB41L3	8431.0
OR7G3	8423.0
LHX2	8400.0
OR2M5	8340.0
OR10Q1	8330.0
OR56A3	8318.0
KCNN2	8247.0
OR12D3	8219.0
TWF2	8217.0
KCNJ2	8197.0
RLBP1	8177.0
RAB3A	8058.0
OR4K14	8023.0
OR51S1	8008.0
OR5AC2	7987.0
PJVK	7944.0
OR8S1	7928.0
GRK7	7840.0
OR4D1	7814.0
SDC2	7776.0
TWF1	7619.0
OR10A7	7575.0
CAPZA1	7559.0
OR5AR1	7513.0
RBP3	7492.0
NAPEPLD	7462.0
APOA2	7456.0
METAP2	7392.0
OR52B6	7384.0
GPC2	7352.0
OR1J2	7318.0
OR4C46	7274.0
ACTB	7138.0
OR2L13	7087.0
SCN2A	7046.0
OR1L4	6920.0
OR5W2	6911.0
GPC5	6905.0
OR2B11	6892.0
LPL	6882.0
OR2Z1	6834.0
HSPG2	6817.0
OR5L2	6757.0
AGRN	6754.0
OR5B3	6741.0
OR4K5	6731.0
OR4D9	6697.0
OR10H4	6683.0
OR52A1	6682.0
OR10A6	6594.0
OR4N2	6531.0
OR2T27	6431.0
OR5H1	6429.0
TPRN	6392.0
DHRS3	6358.0
OR10X1	6340.0
APOC3	6320.0
OR4F15	6311.0
OR2L5	6264.0
RBP4	6237.0
OR2C3	6220.0
NMT2	6208.0
MYO3A	6185.0
EPS8	6167.0
OR5AP2	6150.0
SDC1	6125.0
GPC6	6085.0
OR2M2	6000.0
RGS9BP	5878.0
OR5H6	5860.0
OR8K1	5711.0
OR6K6	5625.0
SNAP25	5460.0
OR5K1	5310.0
OR5AS1	5269.0
OR10K1	5201.0
PCDH15	5177.0
LDB1	5174.0
OR2H1	5153.0
OR1N2	5092.0
TAS2R39	5072.0
OR5P2	5069.0
OR13A1	5030.0
OR7A5	4872.0
OR4C16	4840.0
OR10W1	4830.0
OR2G3	4811.0
VAMP2	4779.0
OR4K1	4690.0
CTBP2	4689.0
CALHM1	4518.0
EPB41L1	4435.0
OR13C2	4416.0
OR51D1	4408.0
APOB	4354.0
OR1B1	4339.0
OR52A5	4318.0
PDE6A	4144.0
TAS2R16	4030.0
OR51I2	3971.0
RDX	3881.0
RETSAT	3867.0
CALM1	3832.0
OR2L2	3802.0
OTOGL	3745.0
OR1L3	3726.0
OR2V1	3706.0
OR2F1	3673.0
OR6B1	3654.0
OR4C12	3648.0
OR2AG2	3614.0
PLS1	3609.0
MYH9	3586.0
OR8A1	3510.0
MYO3B	3505.0
OR6S1	3473.0
OR5A2	3451.0
OPN1SW	3437.0
RIPOR2	3424.0
OR8G1	3358.0
OR1Q1	3239.0
OR6C76	3220.0
OR8H1	3193.0
OR52E8	3121.0
OR6C68	3116.0
RDH12	3089.0
OR5A1	2734.0
OR12D2	2692.0
ESPNL	2685.0
USH1C	2625.0
GNG13	2486.0
DNAJC5	2468.0
TMC2	2414.0
ANO2	2410.0
CAPZB	2363.0
SCN4B	2353.0
OR4N5	2326.0
OR7A10	2164.0
OR8U1	2086.0
LRP10	2084.0
EBF1	2066.0
LRRC52	2008.0
OR14C36	1995.0
TMC1	1797.0
TAS2R5	1781.0
OR13C3	1751.0
OR10T2	1736.0
TTR	1708.0
STRA6	1697.0
OR5I1	1696.0
LRP12	1586.0
OR52J3	1497.0
FNTA	1465.0
GNAL	1453.0
GRK4	1447.0
APOA1	1286.0
OR4S1	1125.0
CHRNA10	1091.0
OR1E1	1062.0
OR1G1	978.0
OR9A4	977.0
OR5M3	886.0
OR10A2	813.0
OR4B1	711.0
OR10H1	706.0
OR6B2	576.0
OR2W1	569.0
OR1L8	385.0
SCN2B	298.0
GNB3	213.0
TRPM5	206.0
USH1G	152.0
WHRN	138.0
METAP1	108.0
CAMKMT	73.0
LRP8	35.0
OR2T4	-54.0
ESPN	-94.0
SCNN1B	-258.0
PLB1	-296.0
OR2M4	-377.0
OR5H15	-384.0
RBP2	-404.0
ATP2B1	-515.0
APOE	-554.0
CHRNA9	-703.0
OR52I2	-738.0
OR11G2	-745.0
CYP4V2	-758.0
OR8J3	-764.0
OR13C9	-812.0
OR13G1	-871.0
DHRS9	-875.0
OR7D2	-918.0
KCNMA1	-935.0
SDC3	-1019.0
OR4K2	-1056.0
OR10G7	-1081.0
OR2AP1	-1100.0
OR5M10	-1133.0
TAS1R3	-1139.0
SLC17A8	-1186.0
SCNN1G	-1370.0
OR2B3	-1375.0
OR2G6	-1385.0
OR1S1	-1410.0
GNB1	-1458.0
LRP1	-1536.0
MYO15A	-1637.0
OR2V2	-1680.0
GNAT3	-1742.0
TAS2R30	-1762.0
OR52D1	-1805.0
OR2T33	-1895.0
OR8K3	-1924.0
SPTBN1	-1925.0
TAS2R50	-1941.0
CACNA1D	-1946.0
OR52E6	-2001.0
KCNQ4	-2007.0
TAS2R14	-2056.0
OR4D10	-2076.0
MYO1C	-2085.0
OR2C1	-2149.0
OR8K5	-2182.0
OR5F1	-2231.0
RPE65	-2284.0
OR51E2	-2378.0
OR9G1	-2412.5
OR9G9	-2412.5
TAS2R10	-2497.0
OTOF	-2508.0
OR13C8	-2520.0
OR6C75	-2570.0
RDH10	-2632.0
CLIC5	-2658.0
REEP1	-2695.0
LDLR	-2698.0
OR51G2	-2761.0
OR1A2	-2800.0
OTOP1	-2813.0
OR1M1	-2828.0
CDH23	-2829.0
ACTG1	-2878.0
SLC24A1	-2886.0
OR14A16	-2997.0
OR10G4	-3098.0
OR5T3	-3200.0
MYO7A	-3277.0
LRP2	-3292.0
PRKCQ	-3312.0
EZR	-3342.0
CAPZA2	-3347.0
KCNMB1	-3350.0
CNGA1	-3354.0
SCNN1A	-3363.0
OR1D2	-3425.0
GNB5	-3454.0
AKR1C3	-3494.0
OR52N1	-3669.0
GPC1	-3689.0
NMT1	-3716.0
ITPR3	-3748.0
OR5V1	-3760.0
RGS9	-3884.0
TAS2R4	-3927.0
OR8D4	-3965.0
OR4X1	-3976.0
OR10S1	-4005.0
BCO2	-4141.0
CIB2	-4163.0
OR6C4	-4168.0
CNGB1	-4197.0
LHFPL5	-4250.0
SAG	-4357.0
OR7D4	-4384.0
OR6Y1	-4392.0
OR2T8	-4428.0
STX1A	-4495.0
CABP1	-4622.0
GNAT1	-4651.0
APOM	-4695.0
OR3A3	-4774.0
SDC4	-4836.0
SCN1B	-4869.0
FNTB	-5038.0
PRKCA	-5111.0
OR6C1	-5161.0
OR52I1	-5227.0
CACNA2D2	-5236.0
OR4A5	-5289.0
PDE6B	-5356.0
TAS1R2	-5382.0
PDE6G	-5385.0
OR5D13	-5441.0
ATP2B2	-5472.0
OR6C3	-5525.0
RDH11	-5546.0
OR2M3	-5586.0
OR7A17	-5618.0
GSN	-5640.0
OR4E2	-5646.0
BCO1	-5659.0
OR52H1	-5674.0
GUCY2D	-5718.0
OR2AE1	-5782.0
TAS1R1	-6026.0
CABP2	-6100.0
TRPM4	-6128.0
OR13D1	-6138.0
OR5T2	-6359.0
OR8J1	-6369.0
OR6K2	-6409.0
OR5B21	-6410.0
ADCY3	-6497.0
ABCA4	-6590.0
OR8U3	-6630.0
OR10K2	-6641.0
TAS2R8	-6655.0
SCNN1D	-6730.0
OR5L1	-6765.0
TAS2R43	-6783.0
RTP2	-6844.0
OR11H6	-6888.0
OR52W1	-6907.0
OR1N1	-6929.0
TAS2R20	-6993.0
OR56A4	-7065.0
OR14J1	-7125.0
TAS2R3	-7206.0
TRIOBP	-7355.0
FSCN2	-7385.0
OR5K2	-7389.0
GRM4	-7413.0
OR10AD1	-7486.0
OR52K1	-7514.0
SPTAN1	-7600.0
STRC	-7638.0
TAS2R7	-7642.0
OR56B1	-7726.0
TMIE	-7746.0
OR10G3	-7749.0
OR8D2	-7765.0
OR1A1	-7797.0
OR10H2	-7840.5
OR10H3	-7844.0
OR7E24	-7862.0
TAS2R41	-7907.0
RTP1	-7945.0
PLCB2	-7966.0
OR13F1	-7974.0
EPS8L2	-7982.0
OR2T1	-8003.0
TAS2R46	-8015.0
OR6K3	-8031.0
OR52B2	-8044.0
OR7C2	-8070.0
TAS2R1	-8095.0
OR10A5	-8257.0
GPIHBP1	-8399.0
GRK1	-8480.0
OR13J1	-8482.0
OR4C45	-8574.0
OR2H2	-8620.0
OR1L6	-8778.0
OR1J4	-8844.0
OR1L1	-8845.0
OR5B12	-8962.0
CALHM3	-8977.0
OTOG	-8986.0
OR10G2	-9015.0
OR2B2	-9054.0
HSD17B1	-9067.0
OR4L1	-9089.0
OR2T11	-9111.0
OR5H2	-9170.0
GNGT1	-9205.0
OR11H4	-9241.0
OR5K4	-9282.0
GUCA1A	-9287.0
GUCA1B	-9393.0
OR10G8	-9429.0
OR2K2	-9474.0
OR5M9	-9506.0
OR4K13	-9508.0
OR2A12	-9533.0
AKR1C1	-9542.0
OR1K1	-9570.0
CLPS	-9619.0
OR6N2	-9635.0
OR56A1	-9668.0
OR5K3	-9913.0
OR52L1	-9930.0
OR8I2	-9969.0

---

REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS

REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS

	1364
set	REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS
setSize	161
pANOVA	4.53e-08
s.dist	0.25
p.adjustANOVA	2.48e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL10L	11612
FAU	10809
PSMB10	10756
RPS3	10729
RPL10A	10664
PSMB11	10643
RPS11	10587
PSMD2	10583
PSMB3	10477
LHX9	10402
ROBO1	10159
RPL37A	10142
PSMA3	10095
RPS15A	10069
PSMD13	9995
PSMA4	9855
RPS27	9839
RPL30	9827
RPL38	9821
ISL1	9816

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL10L	11612.0
FAU	10809.0
PSMB10	10756.0
RPS3	10729.0
RPL10A	10664.0
PSMB11	10643.0
RPS11	10587.0
PSMD2	10583.0
PSMB3	10477.0
LHX9	10402.0
ROBO1	10159.0
RPL37A	10142.0
PSMA3	10095.0
RPS15A	10069.0
PSMD13	9995.0
PSMA4	9855.0
RPS27	9839.0
RPL30	9827.0
RPL38	9821.0
ISL1	9816.0
RPS28	9794.0
PSMB1	9750.0
RPLP1	9720.0
ELOB	9471.0
RPL27	9441.0
PSMF1	9417.0
PSME1	9374.0
RPL22L1	9297.0
RPS5	9280.0
RPLP0	9243.0
RPL15	9182.0
RPL12	9097.0
PSMA6	8867.0
RPL13A	8817.5
RPS27L	8690.0
PSMA5	8596.0
RPL13	8465.0
LHX2	8400.0
RPL26	8334.0
RPS9	8300.0
PSMC5	8218.0
RPL36AL	8178.5
RPL9	8114.0
RPS27A	8106.0
RPS6	8097.0
RBX1	8051.0
RPL35	8050.0
RPL27A	7990.0
PSMD12	7877.0
UBB	7699.0
RPS16	7626.0
MSI1	7570.0
PSMA7	7538.0
SLIT2	7480.0
PSMD4	7467.0
RPS15	7463.0
RPS24	7430.0
RPS10	7327.0
RPL34	7322.0
RPL7	7281.0
RPL23	7239.0
PSME4	6787.0
RPL6	6769.0
RPL17	6670.0
RPL7A	6664.0
RPL18A	6615.0
RPL5	6595.0
PSMB8	6451.0
RPL41	6359.0
PSMB2	6330.0
PSMC3	6214.0
RPL8	6213.0
RPS3A	6057.0
ROBO2	6043.0
RPL23A	5805.0
RPS18	5767.0
RPS14	5716.0
HOXA2	5499.0
UBA52	5407.0
LDB1	5174.0
SEM1	5154.0
RPL26L1	5040.0
PSMC2	4855.0
PSMA1	4619.0
PSMB9	4456.0
ETF1	4345.0
RPL31	4100.0
PSMB5	3878.0
PSMD7	3822.0
CASC3	3686.0
LHX4	3557.0
RPL24	3372.0
RBM8A	3055.0
GSPT1	3039.0
RPL14	3033.0
NCBP2	2801.0
RPS7	2583.0
RPL29	2563.0
RPL4	2539.0
PSMB4	2167.0
PSMD1	2120.0
PSMA2	2110.0
RPL11	1986.0
RPS29	1784.0
MAGOH	1707.0
MAGOHB	1316.0
PSMD8	1241.0
RPL3	1194.0
RPS26	1092.0
PSME2	1076.0
PABPC1	854.0
RPLP2	844.0
NCBP1	823.0
RPS8	808.0
RPL37	742.0
RPL28	382.0
RPS25	379.0
RPL21	189.0
RPS21	153.0
EIF4G1	-8.0
RPL35A	-148.0
RPL19	-158.0
UPF3A	-244.0
RPS13	-895.0
PSMD3	-900.0
RPS12	-1124.0
RPS23	-1129.0
ELOC	-1192.0
RPL18	-1323.0
PSMD14	-1456.0
CUL2	-1526.0
PSMD6	-1616.0
PSMC4	-1875.0
PSMD9	-2211.0
RPS20	-2282.0
ROBO3	-2640.0
RPSA	-2910.0
RPL39L	-3199.0
RNPS1	-3555.0
RPL36	-3656.0
PSMC1	-3824.0
UBC	-3854.0
UPF2	-4120.0
RPL32	-4143.0
PSMB6	-4529.0
LHX3	-4660.0
ZSWIM8	-4662.0
PSMD11	-4817.0
EIF4A3	-4880.0
DAG1	-5764.0
PSMB7	-6036.0
RPS2	-6039.0
PSMD5	-6141.0
USP33	-6387.0
PSME3	-6565.0
RPS19	-6970.0
PSMC6	-6973.0
PSMA8	-7408.0
SLIT1	-8237.0
RPL22	-8308.0
RPL3L	-8798.0

---

REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION

REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION

	151
set	REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION
setSize	87
pANOVA	5.6e-07
s.dist	0.31
p.adjustANOVA	0.000208

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL10L	11612
FAU	10809
RPS3	10729
RPL10A	10664
RPS11	10587
RPL37A	10142
RPS15A	10069
EEF2	9935
RPS27	9839
RPL30	9827
RPL38	9821
RPS28	9794
RPLP1	9720
RPL27	9441
EEF1B2	9432
RPL22L1	9297
RPS5	9280
RPLP0	9243
RPL15	9182
RPL12	9097

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL10L	11612.0
FAU	10809.0
RPS3	10729.0
RPL10A	10664.0
RPS11	10587.0
RPL37A	10142.0
RPS15A	10069.0
EEF2	9935.0
RPS27	9839.0
RPL30	9827.0
RPL38	9821.0
RPS28	9794.0
RPLP1	9720.0
RPL27	9441.0
EEF1B2	9432.0
RPL22L1	9297.0
RPS5	9280.0
RPLP0	9243.0
RPL15	9182.0
RPL12	9097.0
RPL13A	8817.5
RPS27L	8690.0
RPL13	8465.0
RPL26	8334.0
RPS9	8300.0
RPL36AL	8178.5
RPL9	8114.0
RPS27A	8106.0
RPS6	8097.0
RPL35	8050.0
RPL27A	7990.0
RPS16	7626.0
RPS15	7463.0
EEF1A1	7444.0
RPS24	7430.0
RPS10	7327.0
RPL34	7322.0
RPL7	7281.0
RPL23	7239.0
RPL6	6769.0
RPL17	6670.0
RPL7A	6664.0
RPL18A	6615.0
RPL5	6595.0
RPL41	6359.0
RPL8	6213.0
RPS3A	6057.0
RPL23A	5805.0
RPS18	5767.0
RPS14	5716.0
UBA52	5407.0
RPL26L1	5040.0
RPL31	4100.0
RPL24	3372.0
RPL14	3033.0
RPS7	2583.0
RPL29	2563.0
RPL4	2539.0
RPL11	1986.0
RPS29	1784.0
RPL3	1194.0
RPS26	1092.0
RPLP2	844.0
RPS8	808.0
RPL37	742.0
RPL28	382.0
RPS25	379.0
RPL21	189.0
RPS21	153.0
RPL35A	-148.0
RPL19	-158.0
RPS13	-895.0
RPS12	-1124.0
RPS23	-1129.0
RPL18	-1323.0
RPS20	-2282.0
RPSA	-2910.0
RPL39L	-3199.0
RPL36	-3656.0
RPL32	-4143.0
EEF1G	-5559.0
RPS2	-6039.0
EEF1D	-6121.0
RPS19	-6970.0
RPL22	-8308.0
EEF1A2	-8464.0
RPL3L	-8798.0

---

REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE

REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE

	271
set	REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE
setSize	105
pANOVA	6.34e-07
s.dist	0.281
p.adjustANOVA	0.000208

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL10L	11612
FAU	10809
RPS3	10729
RPL10A	10664
RPS11	10587
RPL37A	10142
RPS15A	10069
SEC11C	9921
RPS27	9839
RPL30	9827
RPL38	9821
RPS28	9794
RPLP1	9720
SRP54	9479
RPL27	9441
RPL22L1	9297
RPS5	9280
RPLP0	9243
RPL15	9182
RPL12	9097

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL10L	11612.0
FAU	10809.0
RPS3	10729.0
RPL10A	10664.0
RPS11	10587.0
RPL37A	10142.0
RPS15A	10069.0
SEC11C	9921.0
RPS27	9839.0
RPL30	9827.0
RPL38	9821.0
RPS28	9794.0
RPLP1	9720.0
SRP54	9479.0
RPL27	9441.0
RPL22L1	9297.0
RPS5	9280.0
RPLP0	9243.0
RPL15	9182.0
RPL12	9097.0
RPL13A	8817.5
RPS27L	8690.0
SRP19	8647.0
RPL13	8465.0
RPL26	8334.0
RPS9	8300.0
SRPRA	8226.0
RPL36AL	8178.5
RPL9	8114.0
RPS27A	8106.0
RPS6	8097.0
RPL35	8050.0
RPL27A	7990.0
SSR3	7777.0
SPCS2	7678.0
RPS16	7626.0
RPS15	7463.0
RPS24	7430.0
RPS10	7327.0
RPL34	7322.0
RPL7	7281.0
RPL23	7239.0
RPN2	7033.0
SRP14	6835.0
RPL6	6769.0
RPL17	6670.0
RPL7A	6664.0
RPL18A	6615.0
RPL5	6595.0
RPL41	6359.0
SPCS3	6224.0
RPL8	6213.0
RPS3A	6057.0
RPL23A	5805.0
RPS18	5767.0
RPS14	5716.0
SEC61A1	5590.0
UBA52	5407.0
RPL26L1	5040.0
SRPRB	4650.0
RPL31	4100.0
RPL24	3372.0
TRAM1	3319.0
RPL14	3033.0
SRP9	2664.0
RPS7	2583.0
RPL29	2563.0
RPL4	2539.0
RPL11	1986.0
SEC61B	1813.0
RPS29	1784.0
RPN1	1458.0
RPL3	1194.0
RPS26	1092.0
RPLP2	844.0
RPS8	808.0
RPL37	742.0
RPL28	382.0
RPS25	379.0
SEC11A	363.0
SRP72	338.0
RPL21	189.0
RPS21	153.0
RPL35A	-148.0
RPL19	-158.0
RPS13	-895.0
RPS12	-1124.0
RPS23	-1129.0
SSR1	-1211.0
RPL18	-1323.0
RPS20	-2282.0
DDOST	-2776.0
RPSA	-2910.0
RPL39L	-3199.0
RPL36	-3656.0
RPL32	-4143.0
SPCS1	-4527.0
RPS2	-6039.0
SEC61A2	-6873.0
RPS19	-6970.0
SEC61G	-7692.0
SRP68	-8175.0
SSR2	-8183.0
RPL22	-8308.0
RPL3L	-8798.0

---

REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY

REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY

	1486
set	REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY
setSize	94
pANOVA	1.03e-06
s.dist	0.292
p.adjustANOVA	0.000248

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL10L	11612.0
FAU	10809.0
RPS3	10729.0
RPL10A	10664.0
RPS11	10587.0
RPL37A	10142.0
RPS15A	10069.0
RPS27	9839.0
RPL30	9827.0
RPL38	9821.0
RPS28	9794.0
RPLP1	9720.0
RPL27	9441.0
RPL22L1	9297.0
RPS5	9280.0
RPLP0	9243.0
RPL15	9182.0
RPL12	9097.0
RPL13A	8817.5
RPS27L	8690.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL10L	11612.0
FAU	10809.0
RPS3	10729.0
RPL10A	10664.0
RPS11	10587.0
RPL37A	10142.0
RPS15A	10069.0
RPS27	9839.0
RPL30	9827.0
RPL38	9821.0
RPS28	9794.0
RPLP1	9720.0
RPL27	9441.0
RPL22L1	9297.0
RPS5	9280.0
RPLP0	9243.0
RPL15	9182.0
RPL12	9097.0
RPL13A	8817.5
RPS27L	8690.0
RPL13	8465.0
RPL26	8334.0
RPS9	8300.0
RPL36AL	8178.5
RPL9	8114.0
RPS27A	8106.0
RPS6	8097.0
RPL35	8050.0
RPL27A	7990.0
EIF2S1	7914.0
RPS16	7626.0
RPS15	7463.0
RPS24	7430.0
CEBPG	7348.0
RPS10	7327.0
RPL34	7322.0
RPL7	7281.0
RPL23	7239.0
RPL6	6769.0
RPL17	6670.0
RPL7A	6664.0
RPL18A	6615.0
RPL5	6595.0
ATF3	6452.0
RPL41	6359.0
RPL8	6213.0
RPS3A	6057.0
RPL23A	5805.0
RPS18	5767.0
RPS14	5716.0
UBA52	5407.0
DDIT3	5272.0
RPL26L1	5040.0
RPL31	4100.0
IMPACT	3548.0
RPL24	3372.0
RPL14	3033.0
ATF2	2758.0
RPS7	2583.0
RPL29	2563.0
RPL4	2539.0
ATF4	2108.0
RPL11	1986.0
RPS29	1784.0
RPL3	1194.0
RPS26	1092.0
ASNS	1039.0
RPLP2	844.0
RPS8	808.0
RPL37	742.0
RPL28	382.0
RPS25	379.0
RPL21	189.0
RPS21	153.0
RPL35A	-148.0
RPL19	-158.0
RPS13	-895.0
RPS12	-1124.0
RPS23	-1129.0
RPL18	-1323.0
RPS20	-2282.0
TRIB3	-2295.0
EIF2AK4	-2637.0
CEBPB	-2779.0
RPSA	-2910.0
RPL39L	-3199.0
RPL36	-3656.0
RPL32	-4143.0
GCN1	-5173.0
EIF2S2	-5373.0
RPS2	-6039.0
RPS19	-6970.0
RPL22	-8308.0
RPL3L	-8798.0

---

REACTOME_RRNA_PROCESSING

REACTOME_RRNA_PROCESSING

	1148
set	REACTOME_RRNA_PROCESSING
setSize	192
pANOVA	1.06e-06
s.dist	0.204
p.adjustANOVA	0.000248

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL10L	11612
PWP2	11391
UTP15	11044
ISG20L2	11008
FAU	10809
RPS3	10729
RPL10A	10664
RPS11	10587
EXOSC8	10275
RRP7A	10260
RPL37A	10142
RPS15A	10069
RRP9	10054
RPS27	9839
RPL30	9827
RPL38	9821
RPS28	9794
NOB1	9784
RPLP1	9720
RRP1	9659

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL10L	11612.0
PWP2	11391.0
UTP15	11044.0
ISG20L2	11008.0
FAU	10809.0
RPS3	10729.0
RPL10A	10664.0
RPS11	10587.0
EXOSC8	10275.0
RRP7A	10260.0
RPL37A	10142.0
RPS15A	10069.0
RRP9	10054.0
RPS27	9839.0
RPL30	9827.0
RPL38	9821.0
RPS28	9794.0
NOB1	9784.0
RPLP1	9720.0
RRP1	9659.0
UTP3	9446.0
RPL27	9441.0
RPL22L1	9297.0
RPS5	9280.0
RPLP0	9243.0
EXOSC1	9232.0
RPL15	9182.0
RPL12	9097.0
EXOSC5	9006.0
NOL11	8947.0
RPL13A	8817.5
TRMT112	8763.0
RPS27L	8690.0
NOL6	8615.0
PRORP	8614.0
UTP20	8512.0
RPL13	8465.0
KRR1	8345.0
RPL26	8334.0
WDR3	8323.0
RPS9	8300.0
RPL36AL	8178.5
RPL9	8114.0
RPS27A	8106.0
RPS6	8097.0
UTP4	8092.0
RPL35	8050.0
DDX21	8009.0
RPL27A	7990.0
FTSJ3	7956.0
MPHOSPH6	7832.0
IMP4	7831.0
RPS16	7626.0
FCF1	7586.0
RPS15	7463.0
RPS24	7430.0
NOP14	7421.0
NOP10	7407.0
RPS10	7327.0
RPL34	7322.0
RPL7	7281.0
RPL23	7239.0
RIOK2	6976.0
RRP36	6827.0
RPL6	6769.0
RPP14	6750.0
NHP2	6716.0
UTP6	6706.0
RPL17	6670.0
RPL7A	6664.0
RPL18A	6615.0
RPL5	6595.0
GAR1	6411.0
RPL41	6359.0
WDR75	6294.0
RPL8	6213.0
EXOSC7	6076.0
RPS3A	6057.0
PDCD11	5930.0
BYSL	5920.0
EXOSC9	5806.0
RPL23A	5805.0
RPS18	5767.0
UTP25	5720.0
RPS14	5716.0
RPP40	5599.0
TRMT10C	5520.0
UBA52	5407.0
C1D	5181.0
RPL26L1	5040.0
TFB1M	4935.0
IMP3	4775.0
UTP14C	4612.0
DIS3	4570.0
MRM3	4521.0
RPP30	4507.0
EXOSC6	4471.0
WDR36	4236.0
RPL31	4100.0
MPHOSPH10	4062.0
EXOSC10	3603.0
DCAF13	3589.0
RPL24	3372.0
MTERF4	3138.0
NAT10	3100.0
RPL14	3033.0
WDR12	2993.0
NSUN4	2778.0
RPS7	2583.0
RPL29	2563.0
RPL4	2539.0
NCL	1997.0
RPL11	1986.0
RPS29	1784.0
PNO1	1710.0
FBL	1638.0
PES1	1437.0
RIOK3	1318.0
NOP58	1317.0
TBL3	1298.0
RPP21	1282.0
NIP7	1208.0
RPL3	1194.0
LTV1	1165.0
RPS26	1092.0
UTP11	968.0
WDR18	947.0
EXOSC4	924.0
RPLP2	844.0
RPS8	808.0
RPL37	742.0
RPP25	563.0
DHX37	539.0
PELP1	455.0
DDX49	436.0
WDR43	391.0
RPL28	382.0
RPS25	379.0
EBNA1BP2	351.0
XRN2	230.0
RPL21	189.0
RPS21	153.0
RPL35A	-148.0
RPL19	-158.0
RPP38	-523.0
RPS13	-895.0
BOP1	-1043.0
RPS12	-1124.0
RPS23	-1129.0
TSR1	-1204.0
RPL18	-1323.0
RBM28	-1337.0
GNL3	-1624.0
MTREX	-1681.0
DDX52	-1868.0
SENP3	-1984.0
RPS20	-2282.0
DIMT1	-2510.0
TSR3	-2566.0
RPSA	-2910.0
ELAC2	-3130.0
RCL1	-3135.0
RPL39L	-3199.0
RPL36	-3656.0
CSNK1D	-3676.0
NOP2	-3872.0
RPL32	-4143.0
DDX47	-4361.0
EXOSC3	-4655.0
NOP56	-4722.0
EXOSC2	-4833.0
ERI1	-4858.0
WDR46	-4863.0
UTP18	-5168.0
RIOK1	-5507.0
MRM2	-5690.0
HEATR1	-5770.0
BUD23	-5794.0
RPS2	-6039.0
THUMPD1	-6181.0
MRM1	-6276.0
TEX10	-6434.0
BMS1	-6466.0
RPS19	-6970.0
NOL9	-7115.0
NOC4L	-7296.0
SNU13	-7306.0
EMG1	-8139.0
RPL22	-8308.0
RPL3L	-8798.0
CSNK1E	-9158.0
NOL12	-9239.0

---

REACTOME_RNA_POLYMERASE_I_PROMOTER_ESCAPE

REACTOME_RNA_POLYMERASE_I_PROMOTER_ESCAPE

	1157
set	REACTOME_RNA_POLYMERASE_I_PROMOTER_ESCAPE
setSize	83
pANOVA	1.88e-06
s.dist	0.303
p.adjustANOVA	0.000357

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC6	11639.0
RRN3	11200.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
POLR2L	10239.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
POLR2K	9561.0
H3C8	9291.0
H2BC10	9197.0
TBP	9059.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC6	11639.0
RRN3	11200.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
POLR2L	10239.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
POLR2K	9561.0
H3C8	9291.0
H2BC10	9197.0
TBP	9059.0
H2AC7	8965.5
H2BC7	8965.5
H3C12	8767.0
CDK7	8660.0
H2AC8	8539.0
H3C3	8281.0
H2BC11	8255.0
TAF1A	8186.0
H2AZ1	7981.0
POLR1H	7961.0
H2AC20	7915.0
H4C8	7890.0
H4C12	7649.0
H4C3	7349.0
GTF2H3	7271.0
H4C9	7126.0
TAF1D	6989.0
POLR1C	6895.0
CBX3	6759.0
POLR2H	6733.0
POLR1D	6572.0
H2BC8	6516.0
POLR2E	6396.0
H2AJ	6389.0
H2AZ2	5736.0
H4C5	5555.0
GTF2H1	5260.0
TAF1B	5139.0
POLR1F	4789.0
H2AX	4347.0
H3C11	4283.0
H3C1	3952.0
H3-3A	3716.0
H3-3B	3343.0
UBTF	3135.0
H3C10	2893.0
H4C13	2565.0
MNAT1	1338.0
GTF2H5	1284.0
H4C1	603.0
POLR1G	474.0
H2AC4	375.0
H2BC5	293.0
POLR2F	290.0
H4C6	33.0
H2BC12	15.0
POLR1B	-932.0
ERCC3	-1166.0
POLR1E	-1569.0
H4C2	-1930.0
H2BC13	-2522.0
POLR1A	-4222.0
CCNH	-4515.0
H2BC17	-4820.0
ERCC2	-5812.0
GTF2H4	-6593.0
H4C4	-6811.0
H2BC1	-7243.0
H2BC3	-7283.0
H4C11	-7768.0
H2BC6	-7780.0
TAF1C	-8729.0
H3C6	-9199.0

---

REACTOME_SIGNALING_BY_ROBO_RECEPTORS

REACTOME_SIGNALING_BY_ROBO_RECEPTORS

	605
set	REACTOME_SIGNALING_BY_ROBO_RECEPTORS
setSize	206
pANOVA	1.96e-06
s.dist	0.192
p.adjustANOVA	0.000357

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL10L	11612
FAU	10809
PSMB10	10756
RPS3	10729
RPL10A	10664
PSMB11	10643
RPS11	10587
PSMD2	10583
PSMB3	10477
LHX9	10402
PFN1	10391
ROBO1	10159
RPL37A	10142
PSMA3	10095
RPS15A	10069
PSMD13	9995
PSMA4	9855
RPS27	9839
RPL30	9827
RPL38	9821

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL10L	11612.0
FAU	10809.0
PSMB10	10756.0
RPS3	10729.0
RPL10A	10664.0
PSMB11	10643.0
RPS11	10587.0
PSMD2	10583.0
PSMB3	10477.0
LHX9	10402.0
PFN1	10391.0
ROBO1	10159.0
RPL37A	10142.0
PSMA3	10095.0
RPS15A	10069.0
PSMD13	9995.0
PSMA4	9855.0
RPS27	9839.0
RPL30	9827.0
RPL38	9821.0
ISL1	9816.0
RPS28	9794.0
PSMB1	9750.0
RPLP1	9720.0
ENAH	9521.0
ELOB	9471.0
RPL27	9441.0
PSMF1	9417.0
PSME1	9374.0
RPL22L1	9297.0
RPS5	9280.0
RPLP0	9243.0
RPL15	9182.0
RPL12	9097.0
NELL2	9005.0
PSMA6	8867.0
RPL13A	8817.5
RPS27L	8690.0
PSMA5	8596.0
RPL13	8465.0
LHX2	8400.0
CXCL12	8350.0
RPL26	8334.0
RPS9	8300.0
PSMC5	8218.0
RPL36AL	8178.5
RPL9	8114.0
RPS27A	8106.0
RPS6	8097.0
RBX1	8051.0
RPL35	8050.0
RPL27A	7990.0
PSMD12	7877.0
UBB	7699.0
DCC	7693.0
RPS16	7626.0
MSI1	7570.0
PSMA7	7538.0
SLIT2	7480.0
PSMD4	7467.0
RPS15	7463.0
RPS24	7430.0
RPS10	7327.0
RPL34	7322.0
RPL7	7281.0
RPL23	7239.0
PSME4	6787.0
RPL6	6769.0
RPL17	6670.0
RPL7A	6664.0
RPL18A	6615.0
RPL5	6595.0
PSMB8	6451.0
RPL41	6359.0
PSMB2	6330.0
PSMC3	6214.0
RPL8	6213.0
RPS3A	6057.0
ROBO2	6043.0
RPL23A	5805.0
RPS18	5767.0
RPS14	5716.0
ARHGAP39	5675.0
HOXA2	5499.0
PAK5	5468.0
UBA52	5407.0
CDC42	5404.0
LDB1	5174.0
SEM1	5154.0
RPL26L1	5040.0
PFN2	5021.0
PSMC2	4855.0
PSMA1	4619.0
SRGAP2	4579.0
PSMB9	4456.0
ETF1	4345.0
RPL31	4100.0
ABL1	4013.0
PSMB5	3878.0
SRGAP1	3876.0
PSMD7	3822.0
NCK1	3701.0
CASC3	3686.0
SLIT3	3612.0
LHX4	3557.0
RPL24	3372.0
EVL	3194.0
CAP1	3152.0
SOS2	3136.0
RBM8A	3055.0
GSPT1	3039.0
RPL14	3033.0
SRGAP3	2914.0
NCBP2	2801.0
RPS7	2583.0
RPL29	2563.0
RPL4	2539.0
NCK2	2522.0
PAK6	2339.0
PPP3CB	2190.0
PSMB4	2167.0
PSMD1	2120.0
PSMA2	2110.0
RPL11	1986.0
RPS29	1784.0
MAGOH	1707.0
MAGOHB	1316.0
SOS1	1280.0
PSMD8	1241.0
RPL3	1194.0
VASP	1106.0
RPS26	1092.0
PSME2	1076.0
PABPC1	854.0
RPLP2	844.0
NCBP1	823.0
RPS8	808.0
RPL37	742.0
CXCR4	668.0
RPL28	382.0
RPS25	379.0
NTN1	339.0
CLASP1	197.0
RPL21	189.0
RPS21	153.0
FLRT3	51.0
EIF4G1	-8.0
RPL35A	-148.0
RPL19	-158.0
UPF3A	-244.0
PRKACA	-398.0
PRKACB	-414.0
PAK1	-679.0
RPS13	-895.0
PSMD3	-900.0
RPS12	-1124.0
RPS23	-1129.0
ELOC	-1192.0
RPL18	-1323.0
PSMD14	-1456.0
CUL2	-1526.0
PSMD6	-1616.0
NRP1	-1815.0
PSMC4	-1875.0
ABL2	-2083.0
PSMD9	-2211.0
RPS20	-2282.0
ROBO3	-2640.0
RPSA	-2910.0
PRKAR2A	-3061.0
AKAP5	-3136.0
RPL39L	-3199.0
PRKACG	-3257.0
RNPS1	-3555.0
RPL36	-3656.0
GPC1	-3689.0
CLASP2	-3820.0
PSMC1	-3824.0
UBC	-3854.0
RHOA	-3956.0
UPF2	-4120.0
RPL32	-4143.0
RAC1	-4187.0
MYO9B	-4292.0
PSMB6	-4529.0
LHX3	-4660.0
ZSWIM8	-4662.0
PSMD11	-4817.0
EIF4A3	-4880.0
PRKCA	-5111.0
CAP2	-5345.0
DAG1	-5764.0
PSMB7	-6036.0
RPS2	-6039.0
PSMD5	-6141.0
USP33	-6387.0
PSME3	-6565.0
RPS19	-6970.0
PSMC6	-6973.0
PSMA8	-7408.0
SLIT1	-8237.0
RPL22	-8308.0
PAK2	-8311.0
SRC	-8426.0
PAK4	-8754.0
RPL3L	-8798.0

---

REACTOME_EUKARYOTIC_TRANSLATION_INITIATION

REACTOME_EUKARYOTIC_TRANSLATION_INITIATION

	1149
set	REACTOME_EUKARYOTIC_TRANSLATION_INITIATION
setSize	110
pANOVA	2.92e-06
s.dist	0.258
p.adjustANOVA	0.00048

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL10L	11612
FAU	10809
RPS3	10729
RPL10A	10664
RPS11	10587
EIF2B1	10427
RPL37A	10142
RPS15A	10069
RPS27	9839
RPL30	9827
RPL38	9821
RPS28	9794
RPLP1	9720
EIF2B4	9517
RPL27	9441
RPL22L1	9297
RPS5	9280
RPLP0	9243
EIF4E	9208
RPL15	9182

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL10L	11612.0
FAU	10809.0
RPS3	10729.0
RPL10A	10664.0
RPS11	10587.0
EIF2B1	10427.0
RPL37A	10142.0
RPS15A	10069.0
RPS27	9839.0
RPL30	9827.0
RPL38	9821.0
RPS28	9794.0
RPLP1	9720.0
EIF2B4	9517.0
RPL27	9441.0
RPL22L1	9297.0
RPS5	9280.0
RPLP0	9243.0
EIF4E	9208.0
RPL15	9182.0
EIF2B2	9151.0
RPL12	9097.0
RPL13A	8817.5
RPS27L	8690.0
RPL13	8465.0
RPL26	8334.0
RPS9	8300.0
RPL36AL	8178.5
RPL9	8114.0
RPS27A	8106.0
RPS6	8097.0
RPL35	8050.0
RPL27A	7990.0
EIF2S1	7914.0
RPS16	7626.0
RPS15	7463.0
RPS24	7430.0
RPS10	7327.0
RPL34	7322.0
EIF4A1	7292.0
RPL7	7281.0
RPL23	7239.0
RPL6	6769.0
RPL17	6670.0
RPL7A	6664.0
RPL18A	6615.0
RPL5	6595.0
EIF4A2	6382.0
RPL41	6359.0
RPL8	6213.0
RPS3A	6057.0
RPL23A	5805.0
RPS18	5767.0
RPS14	5716.0
UBA52	5407.0
EIF5B	5116.0
RPL26L1	5040.0
EIF3A	4573.0
RPL31	4100.0
EIF3J	3712.0
RPL24	3372.0
RPL14	3033.0
RPS7	2583.0
RPL29	2563.0
RPL4	2539.0
RPL11	1986.0
EIF3I	1791.0
RPS29	1784.0
EIF4EBP1	1711.0
RPL3	1194.0
RPS26	1092.0
EIF2B5	1070.0
EIF3L	1031.0
PABPC1	854.0
RPLP2	844.0
RPS8	808.0
RPL37	742.0
EIF3G	604.0
RPL28	382.0
RPS25	379.0
EIF3F	244.0
EIF3E	228.0
RPL21	189.0
RPS21	153.0
EIF3K	92.0
EIF4G1	-8.0
RPL35A	-148.0
RPL19	-158.0
RPS13	-895.0
RPS12	-1124.0
RPS23	-1129.0
RPL18	-1323.0
EIF3H	-1351.0
EIF3D	-1491.0
EIF3M	-1565.0
RPS20	-2282.0
RPSA	-2910.0
RPL39L	-3199.0
EIF3B	-3211.0
EIF4B	-3387.0
RPL36	-3656.0
RPL32	-4143.0
EIF5	-4649.0
EIF2S2	-5373.0
RPS2	-6039.0
EIF2B3	-6632.0
RPS19	-6970.0
EIF4H	-8192.0
RPL22	-8308.0
RPL3L	-8798.0

---

REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_HSCS

REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_HSCS

	1282
set	REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_HSCS
setSize	121
pANOVA	5.11e-06
s.dist	0.24
p.adjustANOVA	0.000762

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
PSMB10	10756.0
PSMB11	10643.0
H2AC14	10639.0
PSMD2	10583.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
PSMB3	10477.0
H3C4	10448.0
H2BC26	10335.0
H4C16	10207.0
PSMA3	10095.0
H2BC21	10024.0
H3C2	10000.0
PSMD13	9995.0
H2BC15	9893.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
PSMB10	10756.0
PSMB11	10643.0
H2AC14	10639.0
PSMD2	10583.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
PSMB3	10477.0
H3C4	10448.0
H2BC26	10335.0
H4C16	10207.0
PSMA3	10095.0
H2BC21	10024.0
H3C2	10000.0
PSMD13	9995.0
H2BC15	9893.0
PSMA4	9855.0
PSMB1	9750.0
PSMF1	9417.0
PSME1	9374.0
H3C8	9291.0
H2BC10	9197.0
H2AC7	8965.5
H2BC7	8965.5
PSMA6	8867.0
H3C12	8767.0
CDK7	8660.0
PSMA5	8596.0
H2AC8	8539.0
H3C3	8281.0
H2BC11	8255.0
PSMC5	8218.0
RPS27A	8106.0
H2AZ1	7981.0
H2AC20	7915.0
H4C8	7890.0
PSMD12	7877.0
UBB	7699.0
H4C12	7649.0
PSMA7	7538.0
PSMD4	7467.0
H4C3	7349.0
H4C9	7126.0
PSME4	6787.0
LMO1	6701.0
H2BC8	6516.0
PSMB8	6451.0
H2AJ	6389.0
PSMB2	6330.0
PSMC3	6214.0
GATA2	6033.0
H2AZ2	5736.0
H4C5	5555.0
UBA52	5407.0
LDB1	5174.0
SEM1	5154.0
PSMC2	4855.0
PSMA1	4619.0
KMT2A	4467.0
PSMB9	4456.0
H2AX	4347.0
H3C11	4283.0
TAL1	4197.0
ABL1	4013.0
H3C1	3952.0
PSMB5	3878.0
PSMD7	3822.0
H3-3A	3716.0
ITCH	3506.0
H3-3B	3343.0
H3C10	2893.0
H4C13	2565.0
PSMB4	2167.0
PSMD1	2120.0
PSMA2	2110.0
MNAT1	1338.0
PSMD8	1241.0
PSME2	1076.0
H4C1	603.0
H2AC4	375.0
H2BC5	293.0
H4C6	33.0
H2BC12	15.0
CBFB	-89.0
PSMD3	-900.0
LMO2	-1157.0
YAP1	-1223.0
RUNX1	-1307.0
PSMD14	-1456.0
PSMD6	-1616.0
PSMC4	-1875.0
H4C2	-1930.0
PSMD9	-2211.0
H2BC13	-2522.0
SPI1	-3088.0
PSMC1	-3824.0
UBC	-3854.0
TP73	-4189.0
GATA3	-4387.0
MYB	-4398.0
CCNH	-4515.0
PSMB6	-4529.0
PSMD11	-4817.0
H2BC17	-4820.0
TCF3	-5077.0
PSMB7	-6036.0
PSMD5	-6141.0
TCF12	-6379.0
PSME3	-6565.0
H4C4	-6811.0
PSMC6	-6973.0
H2BC1	-7243.0
H2BC3	-7283.0
PSMA8	-7408.0
H4C11	-7768.0
H2BC6	-7780.0
H3C6	-9199.0

---

REACTOME_SIRT1_NEGATIVELY_REGULATES_RRNA_EXPRESSION

REACTOME_SIRT1_NEGATIVELY_REGULATES_RRNA_EXPRESSION

	737
set	REACTOME_SIRT1_NEGATIVELY_REGULATES_RRNA_EXPRESSION
setSize	60
pANOVA	6.28e-06
s.dist	0.337
p.adjustANOVA	0.000859

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
H3C8	9291.0
H2BC10	9197.0
TBP	9059.0
H2AC7	8965.5
H2BC7	8965.5
H3C12	8767.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
H3C8	9291.0
H2BC10	9197.0
TBP	9059.0
H2AC7	8965.5
H2BC7	8965.5
H3C12	8767.0
H2AC8	8539.0
H3C3	8281.0
H2BC11	8255.0
TAF1A	8186.0
H2AZ1	7981.0
H2AC20	7915.0
H4C8	7890.0
H4C12	7649.0
H4C3	7349.0
H4C9	7126.0
TAF1D	6989.0
H2BC8	6516.0
H2AJ	6389.0
H2AZ2	5736.0
H4C5	5555.0
TAF1B	5139.0
H2AX	4347.0
H3C11	4283.0
H3C1	3952.0
H3-3A	3716.0
H3-3B	3343.0
RRP8	3015.0
H3C10	2893.0
H4C13	2565.0
H4C1	603.0
H2AC4	375.0
H2BC5	293.0
SIRT1	128.0
H4C6	33.0
H2BC12	15.0
H4C2	-1930.0
H2BC13	-2522.0
H2BC17	-4820.0
H4C4	-6811.0
H2BC1	-7243.0
H2BC3	-7283.0
H4C11	-7768.0
H2BC6	-7780.0
TAF1C	-8729.0
H3C6	-9199.0

---

REACTOME_NEGATIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION

REACTOME_NEGATIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION

	853
set	REACTOME_NEGATIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION
setSize	100
pANOVA	7.92e-06
s.dist	0.258
p.adjustANOVA	0.001

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
POLR2L	10239.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
POLR2K	9561.0
SAP18	9299.0
H3C8	9291.0
H2BC10	9197.0
TBP	9059.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
POLR2L	10239.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
POLR2K	9561.0
SAP18	9299.0
H3C8	9291.0
H2BC10	9197.0
TBP	9059.0
H2AC7	8965.5
H2BC7	8965.5
H3C12	8767.0
CDK7	8660.0
H2AC8	8539.0
H3C3	8281.0
H2BC11	8255.0
TAF1A	8186.0
H2AZ1	7981.0
POLR1H	7961.0
SIN3B	7929.0
H2AC20	7915.0
H4C8	7890.0
H4C12	7649.0
H4C3	7349.0
GTF2H3	7271.0
SAP30L	7264.0
H4C9	7126.0
TAF1D	6989.0
POLR1C	6895.0
HDAC1	6863.0
POLR2H	6733.0
POLR1D	6572.0
H2BC8	6516.0
POLR2E	6396.0
H2AJ	6389.0
ARID4B	5817.0
H2AZ2	5736.0
H4C5	5555.0
GTF2H1	5260.0
TAF1B	5139.0
POLR1F	4789.0
SMARCA5	4771.0
H2AX	4347.0
H3C11	4283.0
DNMT1	3953.0
H3C1	3952.0
BAZ2A	3783.0
H3-3A	3716.0
H3-3B	3343.0
MBD2	3169.0
UBTF	3135.0
RRP8	3015.0
H3C10	2893.0
H4C13	2565.0
SIN3A	1712.0
SUDS3	1399.0
MNAT1	1338.0
GTF2H5	1284.0
SAP30BP	746.0
H4C1	603.0
POLR1G	474.0
H2AC4	375.0
H2BC5	293.0
POLR2F	290.0
SIRT1	128.0
H4C6	33.0
H2BC12	15.0
POLR1B	-932.0
ERCC3	-1166.0
POLR1E	-1569.0
H4C2	-1930.0
DNMT3B	-2063.0
HDAC2	-2069.0
H2BC13	-2522.0
SAP30	-3642.0
TTF1	-4061.0
POLR1A	-4222.0
CCNH	-4515.0
SAP130	-4769.0
H2BC17	-4820.0
ERCC2	-5812.0
GTF2H4	-6593.0
H4C4	-6811.0
H2BC1	-7243.0
H2BC3	-7283.0
H4C11	-7768.0
H2BC6	-7780.0
TAF1C	-8729.0
H3C6	-9199.0

---

REACTOME_METABOLISM_OF_RNA

REACTOME_METABOLISM_OF_RNA

	1313
set	REACTOME_METABOLISM_OF_RNA
setSize	675
pANOVA	1.06e-05
s.dist	0.0994
p.adjustANOVA	0.00125

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL10L	11612
SMU1	11494
PWP2	11391
UTP15	11044
ISG20L2	11008
PHF5A	10968
ZNF830	10818
FAU	10809
RBM42	10770
PSMB10	10756
RPS3	10729
RPL10A	10664
PSMB11	10643
WBP11	10633
RPS11	10587
GCFC2	10585
PSMD2	10583
POM121C	10520
PSMB3	10477
MAPK14	10451

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL10L	11612.0
SMU1	11494.0
PWP2	11391.0
UTP15	11044.0
ISG20L2	11008.0
PHF5A	10968.0
ZNF830	10818.0
FAU	10809.0
RBM42	10770.0
PSMB10	10756.0
RPS3	10729.0
RPL10A	10664.0
PSMB11	10643.0
WBP11	10633.0
RPS11	10587.0
GCFC2	10585.0
PSMD2	10583.0
POM121C	10520.0
PSMB3	10477.0
MAPK14	10451.0
EXOSC8	10275.0
RRP7A	10260.0
POLR2L	10239.0
NUP50	10237.0
NXT1	10217.0
CDC5L	10179.0
RPL37A	10142.0
PSMA3	10095.0
RPS15A	10069.0
RRP9	10054.0
RBM39	10038.0
SMN1	10025.5
SMN2	10025.5
PSMD13	9995.0
ISY1	9913.0
TSEN34	9871.0
PSMA4	9855.0
RPS27	9839.0
SNRNP25	9829.0
RPL30	9827.0
RPL38	9821.0
SF3A1	9815.0
SRSF3	9798.0
RPS28	9794.0
NOB1	9784.0
PSMB1	9750.0
ZFP36L1	9745.0
RPLP1	9720.0
YWHAZ	9682.0
NUP35	9667.0
RRP1	9659.0
TRMT6	9623.0
TPRKB	9604.0
POLR2K	9561.0
METTL3	9559.0
A1CF	9536.0
LSM3	9492.0
PHAX	9473.0
UTP3	9446.0
RPL27	9441.0
PSMF1	9417.0
DDX41	9376.0
PSME1	9374.0
CLNS1A	9317.0
PCBP1	9304.0
SAP18	9299.0
RPL22L1	9297.0
TFIP11	9293.0
RPS5	9280.0
POLR2D	9276.0
RPLP0	9243.0
EXOSC1	9232.0
EIF4E	9208.0
RPL15	9182.0
FAM32A	9148.0
UPF1	9099.0
RPL12	9097.0
NUDT21	9030.0
EXOSC5	9006.0
ZNF473	9000.0
NOL11	8947.0
ZFP36	8937.0
PUS7	8928.0
U2AF1L4	8886.0
THG1L	8876.0
PSMA6	8867.0
RPL13A	8817.5
CTU2	8765.0
TRMT112	8763.0
CPSF2	8743.0
SRRM1	8702.0
RPS27L	8690.0
NUP42	8689.0
CDK7	8660.0
NOL6	8615.0
PRORP	8614.0
PSMA5	8596.0
SRRT	8571.0
FUS	8563.0
SNRPD2	8558.0
CSTF3	8538.0
UTP20	8512.0
HNRNPC	8511.0
SRSF9	8502.0
PPIL3	8500.0
RPL13	8465.0
APOBEC3C	8388.0
KRR1	8345.0
RPL26	8334.0
WDR3	8323.0
RPS9	8300.0
PNRC2	8237.0
PSMC5	8218.0
PAPOLA	8214.0
RPL36AL	8178.5
PPIL2	8175.0
U2SURP	8152.0
SF3B1	8141.0
DDX5	8135.0
RPL9	8114.0
NSUN6	8107.0
RPS27A	8106.0
RPS6	8097.0
UTP4	8092.0
RPL35	8050.0
PRCC	8020.0
DDX21	8009.0
RPL27A	7990.0
LENG1	7978.0
FTSJ3	7956.0
SNRPG	7940.0
NUP107	7884.0
PSMD12	7877.0
MPHOSPH6	7832.0
IMP4	7831.0
PRPF4	7811.0
HNRNPF	7758.0
SF3A2	7721.0
UBB	7699.0
WTAP	7682.0
NUP37	7663.0
CHTOP	7653.0
CNOT7	7631.0
RPS16	7626.0
SNW1	7608.0
FCF1	7586.0
PPP1R8	7573.0
RPPH1	7567.0
RAN	7541.0
PSMA7	7538.0
FAM98B	7535.0
PSMD4	7467.0
RPS15	7463.0
RPS24	7430.0
NOP14	7421.0
NOP10	7407.0
THOC5	7403.0
SUGP1	7397.0
HSPB1	7350.0
RPS10	7327.0
RPL34	7322.0
EIF4A1	7292.0
RPL7	7281.0
GTF2H3	7271.0
RPL23	7239.0
SNRPA	7220.0
ADAT1	7199.0
SF3B3	7171.0
POLDIP3	7045.0
RIOK2	6976.0
SRSF1	6894.0
RRP36	6827.0
DHX15	6804.0
PSME4	6787.0
HNRNPA3	6785.0
RPL6	6769.0
TRMT5	6768.0
RPP14	6750.0
FIP1L1	6738.0
POLR2H	6733.0
NHP2	6716.0
PPIL4	6713.0
UTP6	6706.0
SARNP	6693.0
RPL17	6670.0
RPL7A	6664.0
RPL18A	6615.0
RAE1	6609.0
RPL5	6595.0
PRKRIP1	6590.0
NUP98	6483.0
PCBP2	6475.0
MTO1	6469.0
DDX39A	6462.0
PSMB8	6451.0
GAR1	6411.0
POLR2E	6396.0
EIF4A2	6382.0
PRPF18	6375.0
XPO1	6362.0
RPL41	6359.0
PSMB2	6330.0
DHX9	6302.0
WDR75	6294.0
HNRNPK	6283.0
HNRNPA2B1	6248.0
PSMC3	6214.0
RPL8	6213.0
PPWD1	6176.0
LSM1	6126.0
EXOSC7	6076.0
RPS3A	6057.0
YWHAB	6001.0
HNRNPM	5955.0
CWC25	5952.0
PDCD11	5930.0
PRPF3	5924.0
BYSL	5920.0
WDR4	5910.0
HNRNPL	5870.0
SKIC8	5861.0
EXOSC9	5806.0
RPL23A	5805.0
EFTUD2	5772.0
RPS18	5767.0
UTP25	5720.0
RPS14	5716.0
LCMT2	5690.0
PRPF38A	5679.0
PAN2	5644.0
PPIL1	5624.0
RPP40	5599.0
SRSF7	5551.0
PCF11	5546.0
TRMT10C	5520.0
UBA52	5407.0
GTF2H1	5260.0
CDC40	5251.0
TRNT1	5230.0
TRIT1	5207.0
C1D	5181.0
SEM1	5154.0
MAPKAPK2	5129.0
TRMT61B	5078.0
RPL26L1	5040.0
MFAP1	5028.0
NUP205	5001.0
TFB1M	4935.0
RBM5	4934.0
METTL1	4914.0
PSMC2	4855.0
SNRPD3	4852.0
IMP3	4775.0
SNRNP40	4737.0
IGF2BP2	4673.0
SMNDC1	4660.0
PSMA1	4619.0
UTP14C	4612.0
GLE1	4578.0
DIS3	4570.0
HNRNPU	4550.0
PRMT5	4529.0
MRM3	4521.0
BUD31	4508.0
RPP30	4507.0
POP1	4477.0
EXOSC6	4471.0
PSMB9	4456.0
SRSF2	4444.0
CPSF1	4385.0
HNRNPR	4348.0
ETF1	4345.0
WDR36	4236.0
SNRPC	4201.0
CNOT6	4162.0
TSEN2	4135.0
POLR2B	4109.0
RPL31	4100.0
SRSF4	4075.0
MPHOSPH10	4062.0
CSTF2T	4050.0
PPIG	4022.0
DDX6	3989.0
NUP62	3934.0
C2orf49	3932.0
MAPK11	3914.0
PSMB5	3878.0
PSMD7	3822.0
TYW1	3736.0
CNOT11	3707.0
SNRNP35	3705.0
CASC3	3686.0
TCERG1	3660.0
DHX8	3618.0
EXOSC10	3603.0
DCAF13	3589.0
TP53RK	3517.0
LSM5	3480.0
WDR77	3427.0
RPL24	3372.0
TRMU	3360.0
CWF19L2	3315.0
DCPS	3310.0
NUP153	3242.0
TRA2B	3204.0
GTPBP3	3165.0
MTERF4	3138.0
NAT10	3100.0
DDX1	3086.0
RBM8A	3055.0
GSPT1	3039.0
PRPF31	3034.0
RPL14	3033.0
POLR2I	3030.0
WDR12	2993.0
CWC27	2965.0
TUT4	2910.0
SF1	2900.0
TNPO1	2898.0
XPOT	2810.0
NCBP2	2801.0
C9orf78	2794.0
NSUN4	2778.0
SMG8	2777.0
RPS7	2583.0
TRMT44	2569.0
RPL29	2563.0
RPL4	2539.0
CNOT9	2535.0
SRSF5	2449.0
TYW5	2441.0
NUP85	2436.0
UBL5	2431.0
TSEN15	2397.0
OSGEP	2312.0
PRKCD	2272.0
PSMB4	2167.0
ALKBH8	2143.0
PSMD1	2120.0
PSMA2	2110.0
SNRPB2	2093.0
WBP4	2087.0
LSM6	2061.0
SMG7	2057.0
TGS1	2034.0
CCAR1	2009.0
NCL	1997.0
RPL11	1986.0
SNIP1	1943.0
IGF2BP1	1886.0
SUPT5H	1840.0
ADARB1	1815.0
RPS29	1784.0
PNO1	1710.0
MAGOH	1707.0
FBL	1638.0
SRSF6	1601.0
GTF2F1	1584.0
HNRNPH1	1580.0
NSUN2	1488.0
SF3B5	1478.0
PES1	1437.0
CNOT2	1408.0
PPP2R2A	1371.0
RBM25	1369.0
APOBEC3H	1363.0
ADAT2	1342.0
MNAT1	1338.0
RIOK3	1318.0
NOP58	1317.0
MAGOHB	1316.0
TBL3	1298.0
GTF2H5	1284.0
RPP21	1282.0
PSMD8	1241.0
NIP7	1208.0
RPL3	1194.0
ADAR	1181.0
LTV1	1165.0
PAN3	1155.0
RPS26	1092.0
PSME2	1076.0
PUS3	1066.0
SRSF8	1041.0
PPP2R1A	1037.0
PRPF8	1004.0
CSTF1	973.0
UTP11	968.0
DDX20	966.0
WDR18	947.0
BUD13	940.0
EXOSC4	924.0
IK	903.0
PABPC1	854.0
RPLP2	844.0
SNRPF	831.0
NCBP1	823.0
CNOT3	819.0
RPS8	808.0
RTRAF	775.0
RPL37	742.0
POLR2G	642.0
RPP25	563.0
DHX37	539.0
PELP1	455.0
DDX49	436.0
TRMT11	425.0
METTL14	414.0
RANBP2	399.0
WDR43	391.0
RPL28	382.0
SEH1L	380.0
RPS25	379.0
SF3B4	353.0
EBNA1BP2	351.0
POLR2F	290.0
TRDMT1	278.0
NUP43	275.0
PPIH	270.0
CNOT10	259.0
XRN2	230.0
CPSF7	226.0
RPL21	189.0
RPS21	153.0
LSM2	141.0
SF3B2	126.0
USP39	43.0
PABPN1	42.0
EIF4G1	-8.0
SYF2	-16.0
IGF2BP3	-19.0
SART1	-26.0
SNRPN	-31.0
RPL35A	-148.0
DHX38	-149.0
SMG9	-155.0
RPL19	-158.0
UPF3A	-244.0
SNUPN	-317.0
HNRNPA1	-385.0
GEMIN4	-394.0
URM1	-448.0
POP5	-518.0
THOC7	-521.0
RPP38	-523.0
YBX1	-530.0
SMG5	-577.0
CNOT6L	-604.0
RNPC3	-611.0
WDR33	-651.0
PRPF19	-719.0
PPP2CA	-731.0
POM121	-827.0
QTRT2	-832.0
RBM17	-861.0
RPS13	-895.0
PSMD3	-900.0
ANP32A	-1029.0
BOP1	-1043.0
DHX16	-1075.0
NUP88	-1114.0
RPS12	-1124.0
RPS23	-1129.0
CLP1	-1131.0
APOBEC3B	-1137.0
PAIP1	-1147.0
ERCC3	-1166.0
TSR1	-1204.0
NUP160	-1205.0
NSRP1	-1224.0
NUP54	-1247.0
SKIC3	-1251.0
RPL18	-1323.0
RBM28	-1337.0
TRMT9B	-1390.0
NDC1	-1446.0
PSMD14	-1456.0
NXF1	-1531.0
DNAJC8	-1556.0
SNRPA1	-1607.0
PSMD6	-1616.0
GNL3	-1624.0
HNRNPD	-1634.0
SNRNP200	-1652.0
MTREX	-1681.0
XAB2	-1683.0
CDKAL1	-1697.0
CPSF6	-1698.0
GEMIN7	-1713.0
HBS1L	-1718.0
SKIC2	-1738.0
EPRS1	-1792.0
CNOT8	-1806.0
TRMT1	-1809.0
POP4	-1850.0
RTCB	-1859.0
DDX52	-1868.0
PSMC4	-1875.0
SENP3	-1984.0
EDC3	-1987.0
CTU1	-2029.0
SNRNP27	-2107.0
TRMT10A	-2140.0
RNGTT	-2151.0
ZCRB1	-2188.0
BCAS2	-2199.0
PSMD9	-2211.0
LUC7L3	-2248.0
RPS20	-2282.0
SNRPB	-2336.0
AQR	-2337.0
SRSF11	-2435.0
DCP2	-2437.0
THOC6	-2453.0
SYMPK	-2478.0
DIMT1	-2510.0
TSR3	-2566.0
PDCD7	-2583.0
NUP155	-2587.0
SDE2	-2669.0
AKT1	-2798.0
SMG1	-2842.0
CNOT1	-2855.0
RPSA	-2910.0
POLR2A	-2921.0
PNN	-2945.0
CRNKL1	-2986.0
CPSF4	-2999.0
ELAC2	-3130.0
RCL1	-3135.0
CCDC12	-3174.0
RPL39L	-3199.0
U2AF2	-3209.0
TXNL4A	-3214.0
PLRG1	-3265.0
DDX46	-3266.0
QTRT1	-3329.0
EIF4B	-3387.0
LSM4	-3468.0
GTF2F2	-3493.0
RNPS1	-3555.0
PTBP1	-3577.0
HSPA8	-3646.0
RPL36	-3656.0
CSNK1D	-3676.0
TRMT12	-3706.0
PSMC1	-3824.0
CWC22	-3847.0
UBC	-3854.0
NUP210	-3859.0
NOP2	-3872.0
XRN1	-3892.0
KHSRP	-3903.0
PUS1	-3921.0
TUT7	-3929.0
RBM7	-3988.0
PARN	-3994.0
ZMAT5	-4063.0
ZC3H11A	-4100.0
UPF2	-4120.0
RPL32	-4143.0
TYW3	-4286.0
DDX47	-4361.0
LSM10	-4373.0
THOC1	-4445.0
NUP188	-4504.0
TRMT13	-4511.0
CCNH	-4515.0
PSMB6	-4529.0
CACTIN	-4583.0
EDC4	-4604.0
SF3A3	-4624.0
FYTTD1	-4628.0
EXOSC3	-4655.0
NOP56	-4722.0
AAAS	-4776.0
YJU2	-4791.0
PSMD11	-4817.0
PRPF40A	-4826.0
EXOSC2	-4833.0
ERI1	-4858.0
WDR46	-4863.0
EIF4A3	-4880.0
ALYREF	-4908.0
SRRM2	-4975.0
HSPA1A	-5017.0
DCP1A	-5075.0
PRKCA	-5111.0
UTP18	-5168.0
CNOT4	-5256.0
CHERP	-5284.0
RBM22	-5304.0
ACIN1	-5319.0
ZBTB8OS	-5348.0
CWC15	-5400.0
NUP133	-5454.0
RIOK1	-5507.0
ELAVL1	-5576.0
TSEN54	-5592.0
SNRPE	-5663.0
APOBEC3A	-5670.0
MRM2	-5690.0
CPSF3	-5756.0
HEATR1	-5770.0
PPIE	-5771.0
BUD23	-5794.0
PATL1	-5795.0
ERCC2	-5812.0
PUF60	-5822.0
SET	-5834.0
DDX23	-5897.0
TPR	-5901.0
SRSF10	-5953.0
DUS2	-5956.0
NUP58	-5994.0
PSMB7	-6036.0
RPS2	-6039.0
PSMD5	-6141.0
THUMPD1	-6181.0
NUP93	-6202.0
MRM1	-6276.0
NUP214	-6332.0
NT5C3B	-6414.0
TEX10	-6434.0
BMS1	-6466.0
WDR70	-6478.0
ADAT3	-6556.0
PSME3	-6565.0
GEMIN2	-6575.0
THADA	-6589.0
GTF2H4	-6593.0
LSM8	-6822.0
SEC13	-6884.0
RPS19	-6970.0
PSMC6	-6973.0
APOBEC4	-7046.0
NOL9	-7115.0
SNRNP70	-7165.0
POP7	-7231.0
SMG6	-7233.0
NOC4L	-7296.0
SNU13	-7306.0
DHX35	-7351.0
PSMA8	-7408.0
APOBEC1	-7499.0
SRSF12	-7511.0
LSM7	-7543.0
PRPF6	-7544.0
RNMT	-7596.0
SNRPD1	-7601.0
DDX42	-7786.0
DCP1B	-7819.0
CTNNBL1	-7861.0
GEMIN6	-7920.0
ZMAT2	-7965.0
THOC3	-8002.0
EMG1	-8139.0
SLBP	-8246.0
RPL22	-8308.0
POLR2C	-8417.0
GPATCH1	-8507.0
TRMT61A	-8517.0
TNFSF13	-8529.0
TNKS1BP1	-8797.0
RPL3L	-8798.0
DDX39B	-8827.0
LSM11	-8860.0
SLU7	-8919.0
APOBEC2	-9036.0
CSNK1E	-9158.0
NOL12	-9239.0
SNRNP48	-9324.0
GEMIN5	-9449.0
SF3B6	-9789.0
POLR2J	-9831.0

---

REACTOME_TRANSLATION

REACTOME_TRANSLATION

	1152
set	REACTOME_TRANSLATION
setSize	278
pANOVA	1.19e-05
s.dist	0.153
p.adjustANOVA	0.00131

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL10L	11612
MRPL39	11084
N6AMT1	10996
MRPL42	10988
FAU	10809
MRPL50	10755
RPS3	10729
RPL10A	10664
MRPL4	10589
RPS11	10587
AURKAIP1	10577
EIF2B1	10427
MRPL35	10419
MRPS16	10232
RPL37A	10142
MRPL49	10141
RARS1	10105
NARS1	10082
RPS15A	10069
MRPL51	10032

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL10L	11612.0
MRPL39	11084.0
N6AMT1	10996.0
MRPL42	10988.0
FAU	10809.0
MRPL50	10755.0
RPS3	10729.0
RPL10A	10664.0
MRPL4	10589.0
RPS11	10587.0
AURKAIP1	10577.0
EIF2B1	10427.0
MRPL35	10419.0
MRPS16	10232.0
RPL37A	10142.0
MRPL49	10141.0
RARS1	10105.0
NARS1	10082.0
RPS15A	10069.0
MRPL51	10032.0
MRPL16	10008.0
EEF2	9935.0
SEC11C	9921.0
MRPS9	9916.0
RPS27	9839.0
RPL30	9827.0
RPL38	9821.0
MRPL11	9813.0
RPS28	9794.0
RPLP1	9720.0
TSFM	9524.0
EIF2B4	9517.0
SRP54	9479.0
RPL27	9441.0
EEF1B2	9432.0
RPL22L1	9297.0
RPS5	9280.0
RPLP0	9243.0
MRPS30	9237.0
EIF4E	9208.0
MRPL1	9183.0
RPL15	9182.0
EIF2B2	9151.0
RPL12	9097.0
MRPL22	9012.0
OXA1L	8952.0
MRPS7	8835.0
RPL13A	8817.5
MRPL47	8770.0
TRMT112	8763.0
RPS27L	8690.0
WARS2	8688.0
SRP19	8647.0
RPL13	8465.0
RPL26	8334.0
RPS9	8300.0
SRPRA	8226.0
RPL36AL	8178.5
MRPS12	8172.0
RPL9	8114.0
RPS27A	8106.0
RPS6	8097.0
RPL35	8050.0
RPL27A	7990.0
EIF2S1	7914.0
SSR3	7777.0
SPCS2	7678.0
RPS16	7626.0
KARS1	7521.0
RPS15	7463.0
EEF1A1	7444.0
RPS24	7430.0
RPS10	7327.0
RPL34	7322.0
EIF4A1	7292.0
RPL7	7281.0
MRRF	7259.0
RPL23	7239.0
RPN2	7033.0
SRP14	6835.0
RPL6	6769.0
RPL17	6670.0
RPL7A	6664.0
MRPS18B	6662.0
RPL18A	6615.0
RPL5	6595.0
MRPL36	6421.0
EIF4A2	6382.0
RPL41	6359.0
SPCS3	6224.0
RPL8	6213.0
MTIF3	6203.0
MRPL40	6133.0
MRPL13	6127.0
LARS1	6104.0
RPS3A	6057.0
MARS2	6040.0
MRPS24	5900.0
PPA2	5839.0
MRPL55	5837.0
RPL23A	5805.0
RPS18	5767.0
RPS14	5716.0
MRPL57	5623.0
YARS1	5602.0
SEC61A1	5590.0
MRPS35	5580.0
MRPS2	5515.0
MRPL30	5489.0
MTFMT	5462.0
AIMP1	5421.0
UBA52	5407.0
MRPL33	5315.0
SARS2	5303.0
MRPL37	5255.0
MRPL32	5187.0
EIF5B	5116.0
RPL26L1	5040.0
MRPL46	5025.0
MRPL9	5002.0
EARS2	4926.0
YARS2	4846.0
MRPS33	4810.0
MRPL2	4758.0
SRPRB	4650.0
MRPL17	4611.0
EIF3A	4573.0
FARSA	4407.0
ETF1	4345.0
MRPL24	4304.0
MRPS21	4125.0
RPL31	4100.0
MRPS28	3882.0
MRPS27	3838.0
EIF3J	3712.0
MRPL38	3374.0
RPL24	3372.0
MRPS25	3366.0
TRAM1	3319.0
CHCHD1	3155.0
GSPT1	3039.0
RARS2	3036.0
RPL14	3033.0
ERAL1	3004.0
MRPL19	2921.0
SRP9	2664.0
RPS7	2583.0
RPL29	2563.0
RPL4	2539.0
MRPS18C	2256.0
MRPL18	2166.0
MRPS11	2138.0
MRPS23	2056.0
RPL11	1986.0
FARS2	1888.0
PPA1	1814.0
SEC61B	1813.0
EIF3I	1791.0
RPS29	1784.0
MRPL58	1779.0
EIF4EBP1	1711.0
MRPS18A	1693.0
MRPL52	1668.0
RPN1	1458.0
MRPL41	1274.0
MRPL14	1207.0
RPL3	1194.0
RPS26	1092.0
EIF2B5	1070.0
EIF3L	1031.0
PARS2	919.0
TARS1	912.0
PABPC1	854.0
RPLP2	844.0
RPS8	808.0
RPL37	742.0
MRPS6	629.0
EIF3G	604.0
NARS2	419.0
RPL28	382.0
RPS25	379.0
SEC11A	363.0
SRP72	338.0
EIF3F	244.0
MTRF1L	231.0
EIF3E	228.0
RPL21	189.0
TARS2	158.0
RPS21	153.0
EIF3K	92.0
MRPL10	60.0
GFM2	16.0
EIF4G1	-8.0
GADD45GIP1	-62.0
RPL35A	-148.0
LARS2	-156.0
RPL19	-158.0
FARSB	-695.0
MRPL53	-736.0
MRPL12	-891.0
RPS13	-895.0
RPS12	-1124.0
RPS23	-1129.0
SSR1	-1211.0
MRPS14	-1306.0
RPL18	-1323.0
EIF3H	-1351.0
EIF3D	-1491.0
EIF3M	-1565.0
MRPL48	-1747.0
EPRS1	-1792.0
RPS20	-2282.0
MRPS10	-2296.0
CARS1	-2405.0
APEH	-2521.0
MTIF2	-2740.0
DDOST	-2776.0
GFM1	-2852.0
RPSA	-2910.0
DARS2	-2943.0
MRPL27	-3115.0
RPL39L	-3199.0
EIF3B	-3211.0
MARS1	-3215.0
MRPS31	-3247.0
MRPL21	-3297.0
EIF4B	-3387.0
MRPL43	-3644.0
RPL36	-3656.0
AARS2	-3660.0
CARS2	-3683.0
MRPL28	-3720.0
MRPS34	-3871.0
EEF1E1	-3922.0
DARS1	-3940.0
AIMP2	-4051.0
RPL32	-4143.0
HARS2	-4232.0
VARS1	-4447.0
SPCS1	-4527.0
EIF5	-4649.0
MRPS15	-4720.0
MRPL54	-4799.0
MRPL20	-4965.0
IARS2	-4970.0
MRPS26	-5170.0
TUFM	-5201.0
GARS1	-5211.0
EIF2S2	-5373.0
HARS1	-5522.0
EEF1G	-5559.0
MRPL45	-5673.0
WARS1	-5691.0
AARS1	-5780.0
RPS2	-6039.0
EEF1D	-6121.0
PTCD3	-6422.0
EIF2B3	-6632.0
MRPL23	-6667.0
MRPS22	-6819.0
SEC61A2	-6873.0
RPS19	-6970.0
IARS1	-7027.0
MRPL44	-7143.0
VARS2	-7230.0
SEC61G	-7692.0
MRPL34	-7725.0
MRPL15	-7762.0
MRPL3	-7842.0
DAP3	-7943.0
MRPS17	-8029.0
SRP68	-8175.0
SSR2	-8183.0
EIF4H	-8192.0
RPL22	-8308.0
MRPS5	-8375.0
EEF1A2	-8464.0
RPL3L	-8798.0

---

REACTOME_NONSENSE_MEDIATED_DECAY_NMD

REACTOME_NONSENSE_MEDIATED_DECAY_NMD

	1443
set	REACTOME_NONSENSE_MEDIATED_DECAY_NMD
setSize	107
pANOVA	1.32e-05
s.dist	0.244
p.adjustANOVA	0.00136

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL10L	11612.0
FAU	10809.0
RPS3	10729.0
RPL10A	10664.0
RPS11	10587.0
RPL37A	10142.0
RPS15A	10069.0
RPS27	9839.0
RPL30	9827.0
RPL38	9821.0
RPS28	9794.0
RPLP1	9720.0
RPL27	9441.0
RPL22L1	9297.0
RPS5	9280.0
RPLP0	9243.0
RPL15	9182.0
UPF1	9099.0
RPL12	9097.0
RPL13A	8817.5

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL10L	11612.0
FAU	10809.0
RPS3	10729.0
RPL10A	10664.0
RPS11	10587.0
RPL37A	10142.0
RPS15A	10069.0
RPS27	9839.0
RPL30	9827.0
RPL38	9821.0
RPS28	9794.0
RPLP1	9720.0
RPL27	9441.0
RPL22L1	9297.0
RPS5	9280.0
RPLP0	9243.0
RPL15	9182.0
UPF1	9099.0
RPL12	9097.0
RPL13A	8817.5
RPS27L	8690.0
RPL13	8465.0
RPL26	8334.0
RPS9	8300.0
PNRC2	8237.0
RPL36AL	8178.5
RPL9	8114.0
RPS27A	8106.0
RPS6	8097.0
RPL35	8050.0
RPL27A	7990.0
RPS16	7626.0
RPS15	7463.0
RPS24	7430.0
RPS10	7327.0
RPL34	7322.0
RPL7	7281.0
RPL23	7239.0
RPL6	6769.0
RPL17	6670.0
RPL7A	6664.0
RPL18A	6615.0
RPL5	6595.0
RPL41	6359.0
RPL8	6213.0
RPS3A	6057.0
RPL23A	5805.0
RPS18	5767.0
RPS14	5716.0
UBA52	5407.0
RPL26L1	5040.0
ETF1	4345.0
RPL31	4100.0
CASC3	3686.0
RPL24	3372.0
RBM8A	3055.0
GSPT1	3039.0
RPL14	3033.0
NCBP2	2801.0
SMG8	2777.0
RPS7	2583.0
RPL29	2563.0
RPL4	2539.0
SMG7	2057.0
RPL11	1986.0
RPS29	1784.0
MAGOH	1707.0
PPP2R2A	1371.0
MAGOHB	1316.0
RPL3	1194.0
RPS26	1092.0
PPP2R1A	1037.0
PABPC1	854.0
RPLP2	844.0
NCBP1	823.0
RPS8	808.0
RPL37	742.0
RPL28	382.0
RPS25	379.0
RPL21	189.0
RPS21	153.0
EIF4G1	-8.0
RPL35A	-148.0
SMG9	-155.0
RPL19	-158.0
UPF3A	-244.0
SMG5	-577.0
PPP2CA	-731.0
RPS13	-895.0
RPS12	-1124.0
RPS23	-1129.0
RPL18	-1323.0
RPS20	-2282.0
SMG1	-2842.0
RPSA	-2910.0
RPL39L	-3199.0
RNPS1	-3555.0
RPL36	-3656.0
UPF2	-4120.0
RPL32	-4143.0
EIF4A3	-4880.0
DCP1A	-5075.0
RPS2	-6039.0
RPS19	-6970.0
SMG6	-7233.0
RPL22	-8308.0
RPL3L	-8798.0

---

REACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION

REACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION

	852
set	REACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION
setSize	84
pANOVA	1.82e-05
s.dist	0.27
p.adjustANOVA	0.00175

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
POLR2L	10239.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
POLR2K	9561.0
H3C8	9291.0
H2BC10	9197.0
TBP	9059.0
H2AC7	8965.5

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
POLR2L	10239.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
POLR2K	9561.0
H3C8	9291.0
H2BC10	9197.0
TBP	9059.0
H2AC7	8965.5
H2BC7	8965.5
H3C12	8767.0
H2AC8	8539.0
H3C3	8281.0
H2BC11	8255.0
TAF1A	8186.0
SF3B1	8141.0
DDX21	8009.0
H2AZ1	7981.0
POLR1H	7961.0
H2AC20	7915.0
H4C8	7890.0
H4C12	7649.0
H4C3	7349.0
ACTB	7138.0
H4C9	7126.0
TAF1D	6989.0
POLR1C	6895.0
POLR2H	6733.0
POLR1D	6572.0
H2BC8	6516.0
POLR2E	6396.0
H2AJ	6389.0
H2AZ2	5736.0
H4C5	5555.0
TAF1B	5139.0
POLR1F	4789.0
SMARCA5	4771.0
H2AX	4347.0
H3C11	4283.0
H3C1	3952.0
H3-3A	3716.0
H3-3B	3343.0
H3C10	2893.0
H4C13	2565.0
BAZ1B	1630.0
GSK3B	734.0
ERCC6	694.0
H4C1	603.0
POLR1G	474.0
H2AC4	375.0
H2BC5	293.0
POLR2F	290.0
H4C6	33.0
H2BC12	15.0
POLR1B	-932.0
POLR1E	-1569.0
H4C2	-1930.0
MYO1C	-2085.0
H2BC13	-2522.0
EP300	-3520.0
DEK	-4179.0
POLR1A	-4222.0
H2BC17	-4820.0
KAT2A	-5086.0
KAT2B	-6305.0
H4C4	-6811.0
H2BC1	-7243.0
H2BC3	-7283.0
H4C11	-7768.0
H2BC6	-7780.0
MYBBP1A	-8280.0
TAF1C	-8729.0
H3C6	-9199.0

---

REACTOME_AMYLOID_FIBER_FORMATION

REACTOME_AMYLOID_FIBER_FORMATION

	1623
set	REACTOME_AMYLOID_FIBER_FORMATION
setSize	102
pANOVA	2.68e-05
s.dist	0.241
p.adjustANOVA	0.00234

Top enriched genes

Top 20 genes

GeneID	Gene Rank
APCS	11895.0
IAPP	11775.0
ODAM	11737.0
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
SAA1	11178.0
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
SEMG1	10384.0
PSENEN	10355.0
H2BC26	10335.0
APP	10273.0
H4C16	10207.0
CST3	10080.0
GGA3	10078.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
APCS	11895.0
IAPP	11775.0
ODAM	11737.0
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
SAA1	11178.0
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
SEMG1	10384.0
PSENEN	10355.0
H2BC26	10335.0
APP	10273.0
H4C16	10207.0
CST3	10080.0
GGA3	10078.0
H2BC21	10024.0
H3C2	10000.0
APOA4	9996.0
H2BC15	9893.0
BACE1	9817.0
SNCAIP	9684.0
H3C8	9291.0
TSPAN33	9248.0
H2BC10	9197.0
H2AC7	8965.5
H2BC7	8965.5
H3C12	8767.0
H2AC8	8539.0
NAT8	8284.0
H3C3	8281.0
H2BC11	8255.0
RPS27A	8106.0
H2AZ1	7981.0
H2AC20	7915.0
H4C8	7890.0
UBB	7699.0
H4C12	7649.0
H4C3	7349.0
H4C9	7126.0
HSPG2	6817.0
ITM2B	6607.0
H2BC8	6516.0
SNCA	6354.0
B2M	6169.0
H4C5	5555.0
MFGE8	5543.0
UBA52	5407.0
SORL1	4411.0
H2AX	4347.0
H3C11	4283.0
H3C1	3952.0
H3-3A	3716.0
H3-3B	3343.0
UBE2L6	2955.0
H3C10	2893.0
PRKN	2798.0
H4C13	2565.0
TTR	1708.0
APOA1	1286.0
SIAH2	1213.0
CALCA	871.0
H4C1	603.0
APH1A	587.0
H2AC4	375.0
LYZ	312.0
H2BC5	293.0
H4C6	33.0
H2BC12	15.0
PRL	-222.0
TSPAN15	-508.0
APOE	-554.0
SIAH1	-688.0
TGFBI	-926.0
FURIN	-1279.0
H4C2	-1930.0
H2BC13	-2522.0
TSPAN5	-2555.0
APH1B	-3621.0
UBC	-3854.0
GGA2	-3895.0
ADAM10	-4798.0
H2BC17	-4820.0
CALB1	-4979.0
GSN	-5640.0
NCSTN	-5917.0
GGA1	-6553.0
TSPAN14	-6746.0
H4C4	-6811.0
H2BC1	-7243.0
H2BC3	-7283.0
H4C11	-7768.0
H2BC6	-7780.0
LTF	-8479.0
NPPA	-8794.0
INS	-8871.0
FGA	-8988.0
H3C6	-9199.0

---

REACTOME_SELENOAMINO_ACID_METABOLISM

REACTOME_SELENOAMINO_ACID_METABOLISM

	484
set	REACTOME_SELENOAMINO_ACID_METABOLISM
setSize	108
pANOVA	2.71e-05
s.dist	0.234
p.adjustANOVA	0.00234

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL10L	11612
INMT	10981
FAU	10809
RPS3	10729
RPL10A	10664
RPS11	10587
RPL37A	10142
RARS1	10105
RPS15A	10069
RPS27	9839
RPL30	9827
RPL38	9821
RPS28	9794
RPLP1	9720
RPL27	9441
RPL22L1	9297
RPS5	9280
RPLP0	9243
RPL15	9182
RPL12	9097

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL10L	11612.0
INMT	10981.0
FAU	10809.0
RPS3	10729.0
RPL10A	10664.0
RPS11	10587.0
RPL37A	10142.0
RARS1	10105.0
RPS15A	10069.0
RPS27	9839.0
RPL30	9827.0
RPL38	9821.0
RPS28	9794.0
RPLP1	9720.0
RPL27	9441.0
RPL22L1	9297.0
RPS5	9280.0
RPLP0	9243.0
RPL15	9182.0
RPL12	9097.0
RPL13A	8817.5
SEPSECS	8692.0
RPS27L	8690.0
RPL13	8465.0
RPL26	8334.0
RPS9	8300.0
RPL36AL	8178.5
RPL9	8114.0
RPS27A	8106.0
RPS6	8097.0
RPL35	8050.0
RPL27A	7990.0
RPS16	7626.0
KARS1	7521.0
RPS15	7463.0
RPS24	7430.0
RPS10	7327.0
RPL34	7322.0
RPL7	7281.0
RPL23	7239.0
RPL6	6769.0
RPL17	6670.0
RPL7A	6664.0
RPL18A	6615.0
RPL5	6595.0
RPL41	6359.0
RPL8	6213.0
NNMT	6212.0
LARS1	6104.0
RPS3A	6057.0
RPL23A	5805.0
RPS18	5767.0
RPS14	5716.0
AIMP1	5421.0
UBA52	5407.0
RPL26L1	5040.0
SEPHS2	4954.0
RPL31	4100.0
SECISBP2	3416.0
RPL24	3372.0
RPL14	3033.0
RPS7	2583.0
RPL29	2563.0
RPL4	2539.0
GSR	2381.0
RPL11	1986.0
CTH	1977.0
RPS29	1784.0
RPL3	1194.0
RPS26	1092.0
RPLP2	844.0
RPS8	808.0
RPL37	742.0
PAPSS2	482.0
RPL28	382.0
RPS25	379.0
RPL21	189.0
RPS21	153.0
RPL35A	-148.0
RPL19	-158.0
TXNRD1	-403.0
RPS13	-895.0
RPS12	-1124.0
RPS23	-1129.0
AHCY	-1301.0
RPL18	-1323.0
SCLY	-1444.0
EPRS1	-1792.0
PSTK	-2075.0
RPS20	-2282.0
RPSA	-2910.0
RPL39L	-3199.0
MARS1	-3215.0
RPL36	-3656.0
EEF1E1	-3922.0
DARS1	-3940.0
AIMP2	-4051.0
RPL32	-4143.0
EEFSEC	-5120.0
GNMT	-5660.0
MAT1A	-5920.0
RPS2	-6039.0
PAPSS1	-6790.0
RPS19	-6970.0
HNMT	-6991.0
IARS1	-7027.0
RPL22	-8308.0
RPL3L	-8798.0

---

REACTOME_ACTIVATED_PKN1_STIMULATES_TRANSCRIPTION_OF_AR_ANDROGEN_RECEPTOR_REGULATED_GENES_KLK2_AND_KLK3

REACTOME_ACTIVATED_PKN1_STIMULATES_TRANSCRIPTION_OF_AR_ANDROGEN_RECEPTOR_REGULATED_GENES_KLK2_AND_KLK3

	916
set	REACTOME_ACTIVATED_PKN1_STIMULATES_TRANSCRIPTION_OF_AR_ANDROGEN_RECEPTOR_REGULATED_GENES_KLK2_AND_KLK3
setSize	59
pANOVA	3.11e-05
s.dist	0.313
p.adjustANOVA	0.00255

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
H3C8	9291.0
H2BC10	9197.0
H2AC7	8965.5
H2BC7	8965.5
H3C12	8767.0
H2AC8	8539.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
H3C8	9291.0
H2BC10	9197.0
H2AC7	8965.5
H2BC7	8965.5
H3C12	8767.0
H2AC8	8539.0
H3C3	8281.0
H2BC11	8255.0
H2AZ1	7981.0
H2AC20	7915.0
H4C8	7890.0
H4C12	7649.0
H4C3	7349.0
H4C9	7126.0
KLK3	6520.0
H2BC8	6516.0
H2AJ	6389.0
H2AZ2	5736.0
H4C5	5555.0
H2AX	4347.0
H3C11	4283.0
H3C1	3952.0
H3-3A	3716.0
H3-3B	3343.0
H3C10	2893.0
H4C13	2565.0
KDM1A	1167.0
KDM4C	1048.0
H4C1	603.0
H2AC4	375.0
H2BC5	293.0
H4C6	33.0
H2BC12	15.0
NCOA2	13.0
PKN1	-1271.0
H4C2	-1930.0
H2BC13	-2522.0
KLK2	-3691.0
H2BC17	-4820.0
H4C4	-6811.0
H2BC1	-7243.0
H2BC3	-7283.0
H4C11	-7768.0
H2BC6	-7780.0
H3C6	-9199.0

---

REACTOME_DNA_METHYLATION

REACTOME_DNA_METHYLATION

	858
set	REACTOME_DNA_METHYLATION
setSize	58
pANOVA	4.64e-05
s.dist	0.309
p.adjustANOVA	0.00357

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
H3C8	9291.0
H2BC10	9197.0
H2AC7	8965.5
H2BC7	8965.5
H3C12	8767.0
H2AC8	8539.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
H3C8	9291.0
H2BC10	9197.0
H2AC7	8965.5
H2BC7	8965.5
H3C12	8767.0
H2AC8	8539.0
H3C3	8281.0
H2BC11	8255.0
H2AZ1	7981.0
H2AC20	7915.0
H4C8	7890.0
H4C12	7649.0
H4C3	7349.0
H4C9	7126.0
H2BC8	6516.0
H2AJ	6389.0
H2AZ2	5736.0
H4C5	5555.0
H2AX	4347.0
H3C11	4283.0
DNMT1	3953.0
H3C1	3952.0
H3-3A	3716.0
H3-3B	3343.0
H3C10	2893.0
H4C13	2565.0
H4C1	603.0
H2AC4	375.0
H2BC5	293.0
H4C6	33.0
H2BC12	15.0
DNMT3L	-78.0
UHRF1	-192.0
H4C2	-1930.0
DNMT3B	-2063.0
H2BC13	-2522.0
H2BC17	-4820.0
DNMT3A	-5036.0
H4C4	-6811.0
H2BC1	-7243.0
H2BC3	-7283.0
H4C11	-7768.0
H2BC6	-7780.0
H3C6	-9199.0

---

REACTOME_PRC2_METHYLATES_HISTONES_AND_DNA

REACTOME_PRC2_METHYLATES_HISTONES_AND_DNA

	440
set	REACTOME_PRC2_METHYLATES_HISTONES_AND_DNA
setSize	65
pANOVA	4.78e-05
s.dist	0.292
p.adjustANOVA	0.00357

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
AEBP2	9465.0
H3C8	9291.0
H2BC10	9197.0
H2AC7	8965.5
H2BC7	8965.5
H3C12	8767.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
AEBP2	9465.0
H3C8	9291.0
H2BC10	9197.0
H2AC7	8965.5
H2BC7	8965.5
H3C12	8767.0
H2AC8	8539.0
H3C3	8281.0
H2BC11	8255.0
H2AZ1	7981.0
H2AC20	7915.0
H4C8	7890.0
H4C12	7649.0
H4C3	7349.0
H4C9	7126.0
H2BC8	6516.0
EZH2	6449.0
H2AJ	6389.0
SUZ12	6038.0
H2AZ2	5736.0
H4C5	5555.0
H2AX	4347.0
H3C11	4283.0
PHF19	4265.0
PHF1	4056.0
DNMT1	3953.0
H3C1	3952.0
H3-3A	3716.0
H3-3B	3343.0
H3C10	2893.0
H4C13	2565.0
H4C1	603.0
H2AC4	375.0
H2BC5	293.0
H4C6	33.0
H2BC12	15.0
RBBP4	-35.0
H4C2	-1930.0
DNMT3B	-2063.0
H2BC13	-2522.0
MTF2	-3188.0
JARID2	-4399.0
EED	-4609.0
H2BC17	-4820.0
DNMT3A	-5036.0
H4C4	-6811.0
H2BC1	-7243.0
H2BC3	-7283.0
H4C11	-7768.0
H2BC6	-7780.0
H3C6	-9199.0

---

REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS

REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS

	130
set	REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS
setSize	123
pANOVA	7.3e-05
s.dist	-0.207
p.adjustANOVA	0.00521

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GPD1	-9798
PLA2G2F	-9596
PLD4	-9584
CPNE3	-9061
PLA2G2E	-8542
GPAT2	-8538
PLA2G10	-8403
SLC44A4	-8396
PLBD1	-8043
ETNPPL	-8025
CHPT1	-7991
PCYT2	-7555
STARD7	-7513
GPD1L	-7504
PLD6	-7423
LPGAT1	-7350
PLAAT3	-7332
PISD	-6946
AGPAT3	-6892
SLC44A2	-6737

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GPD1	-9798
PLA2G2F	-9596
PLD4	-9584
CPNE3	-9061
PLA2G2E	-8542
GPAT2	-8538
PLA2G10	-8403
SLC44A4	-8396
PLBD1	-8043
ETNPPL	-8025
CHPT1	-7991
PCYT2	-7555
STARD7	-7513
GPD1L	-7504
PLD6	-7423
LPGAT1	-7350
PLAAT3	-7332
PISD	-6946
AGPAT3	-6892
SLC44A2	-6737
PLA2G4F	-6552
ETNK2	-6232
PTPMT1	-6206
LPCAT4	-6025
MIGA2	-5862
CPNE1	-5832
DGAT2	-5735
LPCAT3	-5716
MFSD2A	-5698
SLC44A1	-5626
PNPLA2	-5610
CPNE7	-5538
PITPNM2	-5381
ABHD3	-5341
GPD2	-5333
STARD10	-5317
GPCPD1	-5189
PEMT	-5163
LPCAT1	-5067
AGPAT2	-4917
PLA2G5	-4862
PLAAT2	-4829
CDIPT	-4666
PLA2G2A	-4562
DDHD1	-4524
TMEM86B	-4325
BCHE	-4097
PLA2G15	-4019
CPNE6	-3974
PLAAT5	-3439
OSBPL5	-3364
PITPNM3	-3062
ETNK1	-2802
PCTP	-2177
PITPNM1	-2129
OSBPL8	-2103
PLD2	-1977
PLA2G2D	-1919
PLA2G3	-1916
CSNK2A1	-1847
PLA2G4C	-1746
PLA2G4B	-1661
LPIN1	-1505
PLD1	-1368
PLA2G6	-1201
LPIN2	-1151
DGAT1	-1142
MBOAT1	-996
PCYT1A	-888
AGPAT5	-686
PLB1	-296
AGPAT4	-213
PNPLA8	-136
SLC44A3	-131
ABHD4	-73
PTDSS2	47
GPAT4	129
CSNK2A2	162
CHKA	547
LCLAT1	733
ACHE	750
CEPT1	790
MGLL	841
PTDSS1	1045
CHKB	1058
LIPI	1390
AGPAT1	1590
PITPNB	1628
ALPI	1716
PLA2G4D	2129
PLD3	2390
MIGA1	2451
PLAAT1	2454
CDS1	2613
CRLS1	2637
SLC44A5	2807
CSNK2B	2924
OSBPL10	2949
PHOSPHO1	3060
AGK	3367
CDS2	3387
PLA2G1B	3941
GNPAT	4146
PLA2G12A	4344
SELENOI	4498
PLA1A	4601
HADHB	4716
PLA2R1	4875
MBOAT7	4963
PGS1	5381
CHAT	6196
DDHD2	7025
LPIN3	7284
MBOAT2	7372
PNPLA3	7986
PLA2G4A	8925
LPCAT2	9046
GPAM	9513
ACP6	9662
PLAAT4	9767
HADHA	9828
LIPH	10076
PLA2G4E	10924

---

REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS

REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS

	754
set	REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS
setSize	13
pANOVA	9.28e-05
s.dist	-0.626
p.adjustANOVA	0.00635

Top enriched genes

Top 20 genes

GeneID	Gene Rank
AQP7	-9890
AQP12A	-9800
AQP2	-9209
AQP5	-8811
AQP3	-8198
AQP1	-8101
AQP8	-7879
AQP10	-7820
AQP6	-6813
MIP	-6381
AQP9	1304
AQP4	1981
AQP11	3434

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
AQP7	-9890
AQP12A	-9800
AQP2	-9209
AQP5	-8811
AQP3	-8198
AQP1	-8101
AQP8	-7879
AQP10	-7820
AQP6	-6813
MIP	-6381
AQP9	1304
AQP4	1981
AQP11	3434

---

REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS

REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS

	179
set	REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS
setSize	111
pANOVA	0.000101
s.dist	0.214
p.adjustANOVA	0.00662

Top enriched genes

Top 20 genes

GeneID	Gene Rank
UQCRB	11808
ATP5PO	11189
COX6B1	11101
NDUFA4	10897
NDUFA8	10698
NDUFB5	10695
ATP5MC1	10565
TIMMDC1	10471
ATP5MG	10328
NDUFB3	10093
NDUFB1	9888
NDUFA3	9660
NDUFS4	9658
UQCRH	9525
NDUFA9	9323
NDUFS7	9301
TMEM126B	9106
COX6A1	9035
NDUFB4	8960
COX8A	8799

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
UQCRB	11808
ATP5PO	11189
COX6B1	11101
NDUFA4	10897
NDUFA8	10698
NDUFB5	10695
ATP5MC1	10565
TIMMDC1	10471
ATP5MG	10328
NDUFB3	10093
NDUFB1	9888
NDUFA3	9660
NDUFS4	9658
UQCRH	9525
NDUFA9	9323
NDUFS7	9301
TMEM126B	9106
COX6A1	9035
NDUFB4	8960
COX8A	8799
ATP5PB	8717
COX7A2L	8528
COX20	8391
ETFDH	8303
ATP5PF	8240
NDUFAF4	8230
NDUFV2	8158
NDUFV3	8125
NDUFA6	7985
UQCRC2	7911
NDUFAF7	7910
COX5B	7869
NDUFS1	7683
UCP2	7602
UQCR10	7523
ATP5ME	7489
CYCS	7449
NUBPL	7338
NDUFS6	7214
ATP5F1A	6728
COQ10B	6680
SDHC	6639
ETFB	6380
ATP5F1D	6361
COX6C	6280
NDUFAF1	5927
UQCR11	5771
ATP5MC3	5428
SLC25A27	5364
NDUFB6	5346
NDUFAF2	5206
COX4I1	5182
SCO1	5014
COX11	4320
COX18	4252
COQ10A	3899
ATP5F1B	3853
NDUFS3	3776
SDHB	3538
UQCRC1	3391
TMEM186	3170
COX7C	3091
ATP5MC2	2765
ECSIT	2406
NDUFS5	2404
NDUFAF5	1873
NDUFB10	1753
NDUFB7	1649
SDHD	1509
DMAC2L	1492
NDUFA2	1456
ATP5PD	1042
NDUFA12	992
NDUFC1	930
UCP1	848
NDUFB2	842
NDUFA11	700
COX5A	695
UQCRQ	585
TACO1	523
NDUFAF3	519
NDUFA7	320
LRPPRC	-365
ETFA	-426
NDUFA10	-922
ATP5MF	-1084
NDUFC2	-1334
ATP5F1C	-1335
ACAD9	-1350
COA1	-2402
NDUFAF6	-2543
NDUFS8	-2728
COX19	-2736
TRAP1	-3017
COX16	-3336
COX14	-4123
SURF1	-4207
SCO2	-4239
NDUFA13	-4849
NDUFA5	-5034
CYC1	-5055
NDUFS2	-5361
NDUFB8	-5594
NDUFB9	-5833
PM20D1	-5856
SDHA	-6233
ATP5F1E	-6470
UQCRFS1	-6502
NDUFAB1	-7763
NDUFV1	-9072
UCP3	-9633

---

REACTOME_ASSEMBLY_OF_THE_ORC_COMPLEX_AT_THE_ORIGIN_OF_REPLICATION

REACTOME_ASSEMBLY_OF_THE_ORC_COMPLEX_AT_THE_ORIGIN_OF_REPLICATION

	1091
set	REACTOME_ASSEMBLY_OF_THE_ORC_COMPLEX_AT_THE_ORIGIN_OF_REPLICATION
setSize	62
pANOVA	0.000119
s.dist	0.282
p.adjustANOVA	0.00753

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
H3C8	9291.0
H2BC10	9197.0
H2AC7	8965.5
H2BC7	8965.5
H3C12	8767.0
H2AC8	8539.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
H3C8	9291.0
H2BC10	9197.0
H2AC7	8965.5
H2BC7	8965.5
H3C12	8767.0
H2AC8	8539.0
H3C3	8281.0
H2BC11	8255.0
ORC1	8043.0
H2AZ1	7981.0
H2AC20	7915.0
H4C8	7890.0
H4C12	7649.0
H4C3	7349.0
H4C9	7126.0
ORC6	6542.0
H2BC8	6516.0
H2AJ	6389.0
H2AZ2	5736.0
H4C5	5555.0
H2AX	4347.0
H3C11	4283.0
H3C1	3952.0
ORC2	3818.0
H3-3A	3716.0
H3-3B	3343.0
H3C10	2893.0
H4C13	2565.0
H4C1	603.0
H2AC4	375.0
H2BC5	293.0
H4C6	33.0
H2BC12	15.0
ORC4	-706.0
H4C2	-1930.0
ORC3	-2289.0
H2BC13	-2522.0
KPNA1	-2867.0
ORC5	-4388.0
H2BC17	-4820.0
KPNA6	-5337.0
KPNB1	-6735.0
H4C4	-6811.0
H2BC1	-7243.0
H2BC3	-7283.0
H4C11	-7768.0
H2BC6	-7780.0
H3C6	-9199.0

---

REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

	1161
set	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION
setSize	1336
pANOVA	0.000129
s.dist	0.0624
p.adjustANOVA	0.00786

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ZNF676	11943.0
RETN	11861.0
ZNF101	11786.0
ZNF735	11762.0
FASLG	11647.0
H2AC6	11639.0
CTLA4	11564.0
ZNF583	11549.0
FOXO6	11449.0
RBBP5	11312.0
ZNF439	11292.0
ZNF112	11277.0
ZNF730	11253.0
ZNF233	11247.0
ZNF354C	11243.0
ZNF677	11216.0
H2AC18	11198.5
H2AC19	11198.5
ZNF304	11142.0
ZNF468	11123.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ZNF676	11943.0
RETN	11861.0
ZNF101	11786.0
ZNF735	11762.0
FASLG	11647.0
H2AC6	11639.0
CTLA4	11564.0
ZNF583	11549.0
FOXO6	11449.0
RBBP5	11312.0
ZNF439	11292.0
ZNF112	11277.0
ZNF730	11253.0
ZNF233	11247.0
ZNF354C	11243.0
ZNF677	11216.0
H2AC18	11198.5
H2AC19	11198.5
ZNF304	11142.0
ZNF468	11123.0
COX6B1	11101.0
LAMTOR5	11079.0
ZIM2	11078.0
ZNF600	11058.0
ZNF382	11050.0
H2BC14	11048.0
ZKSCAN1	10989.0
ZNF285	10978.0
ZNF699	10964.0
ZNF14	10947.0
NR4A2	10898.0
NDUFA4	10897.0
ZNF582	10889.0
ZNF354A	10805.0
PSMB10	10756.0
PCK1	10694.0
POMC	10676.0
GADD45A	10652.0
PSMB11	10643.0
H2AC14	10639.0
ZNF273	10627.0
GTF2B	10612.0
PSMD2	10583.0
ZNF442	10575.0
TWIST2	10572.0
ZNF154	10532.0
SFN	10530.0
ZNF189	10514.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
ESRRG	10492.0
PSMB3	10477.0
ZNF776	10460.0
ZFP37	10457.0
MAPK14	10451.0
H3C4	10448.0
SYT10	10443.0
TAF13	10390.0
SERPINB13	10354.0
H2BC26	10335.0
MED20	10313.0
ZNF529	10293.0
POLR2L	10239.0
H4C16	10207.0
ZFP2	10194.0
ABCA6	10166.0
PRKAB2	10161.0
ZNF770	10130.0
PSMA3	10095.0
ZNF234	10088.0
ZNF235	10086.0
ZFP1	10081.0
SIRT3	10079.0
ZNF680	10067.0
ZNF682	10060.0
RGCC	10043.0
RNU12	10031.0
H2BC21	10024.0
ZNF230	10016.0
ICE1	10011.0
IGFBP3	10005.0
ZNF713	10003.0
H3C2	10000.0
PSMD13	9995.0
ZNF479	9992.0
REST	9962.0
ZNF528	9954.0
PERP	9946.0
GLS2	9911.0
H2BC15	9893.0
TAF9	9880.0
PSMA4	9855.0
MYC	9848.0
MSX2	9831.0
SOX2	9810.0
ZNF79	9804.0
SRSF3	9798.0
HNF4A	9787.0
TAF15	9785.0
ZNF586	9773.0
PSMB1	9750.0
RPA2	9717.0
ZNF785	9695.0
YWHAZ	9682.0
RAD9B	9673.0
ZNF33A	9642.0
SKP1	9634.0
ZNF559	9621.0
TJP1	9610.0
ZNF565	9586.0
POLR2K	9561.0
ZNF669	9542.0
ZNF706	9531.0
GPAM	9513.0
PHAX	9473.0
ELOB	9471.0
MED17	9468.0
SPP1	9458.0
SMARCC1	9454.0
BRIP1	9423.0
PSMF1	9417.0
INTS5	9409.0
PSME1	9374.0
TRIAP1	9363.0
ZNF12	9357.0
GATA4	9352.0
ZNF556	9313.0
POU4F2	9303.0
H3C8	9291.0
DPY30	9285.0
POLR2D	9276.0
COL1A1	9234.0
PRMT6	9225.0
GPS2	9221.0
TWIST1	9215.0
BTG1	9204.0
H2BC10	9197.0
ZNF620	9146.0
LAMTOR1	9143.0
TSC1	9072.0
RELA	9063.0
TNFRSF10A	9061.0
TBP	9059.0
GPI	9050.0
HEY1	9049.0
COX6A1	9035.0
GLI2	9032.0
NUDT21	9030.0
ZNF473	9000.0
HSPD1	8997.0
MED4	8985.0
ZNF670	8976.0
ZNF703	8967.0
H2AC7	8965.5
H2BC7	8965.5
TAF7	8962.0
ZNF227	8957.0
ZNF253	8948.0
ZNF625	8943.0
ZNF17	8909.0
U2AF1L4	8886.0
DDIT4	8878.0
TTC5	8871.0
PSMA6	8867.0
ITGBL1	8841.0
ZNF274	8832.0
ZNF211	8805.0
COX8A	8799.0
INTS7	8793.0
SERPINE1	8789.0
ZNF224	8769.0
H3C12	8767.0
MED1	8758.0
CPSF2	8743.0
SRRM1	8702.0
GRIN2B	8696.0
INTS4	8665.0
CDK7	8660.0
SMAD6	8650.0
ZNF749	8633.0
ZNF610	8613.0
PSMA5	8596.0
ZNF471	8587.0
ZNF195	8582.0
SRRT	8571.0
H2AC8	8539.0
CSTF3	8538.0
PRKAA2	8530.0
COX7A2L	8528.0
ZNF440	8518.0
SRSF9	8502.0
GP1BA	8432.0
GLI3	8414.0
COX20	8391.0
ZNF681	8370.0
TAF11	8367.0
ZNF2	8347.0
WWTR1	8325.0
PTPN11	8317.0
ZNF334	8313.0
ZNF486	8292.0
RPAP2	8289.0
DLX5	8286.0
H3C3	8281.0
CHEK2	8262.0
ZNF337	8261.0
H2BC11	8255.0
EGFR	8241.0
GRIN2A	8238.0
ZNF461	8233.0
PSMC5	8218.0
PAPOLA	8214.0
CDK9	8203.0
GTF2E1	8182.0
MOBP	8181.0
ZNF490	8157.0
NEDD4L	8148.0
ZNF155	8123.0
RPS27A	8106.0
ZNF569	8100.0
ZSCAN25	8061.0
ZNF649	8053.0
RBX1	8051.0
CBX8	8040.0
ZNF19	8034.0
ZNF557	8026.0
PF4	8014.0
CDKN2A	7994.0
H2AZ1	7981.0
RNF2	7967.0
SNRPG	7940.0
SIN3B	7929.0
GEM	7916.0
H2AC20	7915.0
H4C8	7890.0
BCL2L11	7888.0
MIR132	7882.0
RBPJ	7881.0
PSMD12	7877.0
COX5B	7869.0
RBFOX1	7865.0
MAP2K6	7860.0
ZFHX3	7847.0
RSPO3	7846.0
PRDX5	7827.0
SESN1	7754.0
NELFB	7739.0
ZNF585A	7738.0
RAD50	7710.0
UBB	7699.0
SMARCE1	7679.0
ZNF566	7676.0
ZNF268	7669.0
CHTOP	7653.0
H4C12	7649.0
CNOT7	7631.0
ZNF484	7613.0
SNW1	7608.0
FOS	7607.0
CDKN1B	7600.0
PPP1R13L	7577.0
CITED2	7560.0
SMARCD2	7550.0
ZNF480	7546.0
PSMA7	7538.0
ZKSCAN4	7527.0
ARNT2	7495.0
NFYA	7491.0
PSMD4	7467.0
CYCS	7449.0
ZNF671	7432.0
THOC5	7403.0
PPARGC1A	7385.0
H4C3	7349.0
TBX5	7337.0
RABGGTB	7279.0
GTF2H3	7271.0
RFC4	7219.0
IL2	7200.0
ZNF721	7187.0
KLF4	7174.0
ZNF577	7154.0
H4C9	7126.0
ZNF25	7118.0
CAMK4	7105.0
ZNF736	7082.0
ZNF221	7073.0
ZNF729	7070.0
BRD1	7066.0
ZNF140	7058.0
ZNF286A	7049.0
POLDIP3	7045.0
TCF7	7044.0
ZNF317	7043.0
MAF	7013.0
ESR2	7005.0
ZNF678	6980.0
ZNF570	6973.0
ZKSCAN7	6953.0
TFAP2D	6937.0
ZNF667	6919.0
EAF2	6915.0
ZNF26	6897.0
SRSF1	6894.0
PHC3	6883.0
ZNF215	6881.0
HDAC1	6863.0
ZNF717	6862.0
SNAPC5	6854.0
MEAF6	6829.0
RAD17	6802.0
KCTD1	6795.0
ZNF746	6789.0
PSME4	6787.0
FBXO32	6780.0
CBX3	6759.0
FIP1L1	6738.0
RARB	6736.0
POLR2H	6733.0
CDK5R1	6726.0
ZNF708	6720.0
ZNF43	6707.0
ZNF615	6704.0
LMO1	6701.0
SARNP	6693.0
TAF12	6685.0
SESN3	6666.0
ZNF197	6620.0
EXO1	6618.0
IWS1	6557.0
ZNF267	6522.0
ZNF740	6521.0
H2BC8	6516.0
ZNF30	6504.0
BDNF	6492.0
KIT	6487.0
ZNF347	6474.0
ZNF548	6463.0
DDX39A	6462.0
PSMB8	6451.0
EZH2	6449.0
ZNF621	6399.0
POLR2E	6396.0
LIFR	6393.0
H2AJ	6389.0
ELL3	6363.0
XPO1	6362.0
ZNF790	6348.0
PAF1	6337.0
ZNF799	6335.0
PSMB2	6330.0
TGFA	6327.0
SNAPC4	6318.0
SMAD1	6285.0
COX6C	6280.0
ZNF446	6271.0
NR3C2	6259.0
ESRRB	6258.0
PSMC3	6214.0
ZNF223	6186.0
ZNF214	6184.0
NR2E1	6174.0
KCTD15	6152.0
ZNF264	6120.0
SUPT6H	6118.0
ZNF585B	6113.0
ZNF606	6103.0
INTS2	6098.0
ICE2	6093.0
LAMTOR2	6067.0
RHEB	6060.0
RAD51	6045.0
RMI2	6044.0
SUZ12	6038.0
INTS12	6035.0
GATA2	6033.0
RORB	6014.0
YWHAB	6001.0
ZNF774	5998.0
ZNF248	5986.0
RBFOX3	5967.0
ZIK1	5964.0
ZNF664	5949.0
TNFRSF10D	5940.0
NR1I3	5923.0
ITGA4	5921.0
DLX6	5916.0
FKBP5	5915.0
FOXG1	5889.0
TEAD4	5884.0
SKIC8	5861.0
CDC25C	5843.0
RNF34	5840.0
ELL2	5825.0
BMP2	5794.0
ESRRA	5787.0
OPRM1	5755.0
ZNF10	5751.0
PIP4K2C	5750.0
H2AZ2	5736.0
MED8	5712.0
ARNT	5688.0
FAS	5687.0
RRAGD	5685.0
ATAD2	5655.0
TAF5	5606.0
ZNF34	5604.0
H4C5	5555.0
SRSF7	5551.0
ZNF791	5549.0
PCF11	5546.0
ZNF624	5536.0
KRAS	5535.0
ZNF875	5453.0
GTF2A1	5436.0
UBA52	5407.0
ZNF141	5401.0
RBL2	5397.0
EPC1	5394.0
ZNF792	5369.0
IGFBP1	5356.0
TP53AIP1	5354.0
ZNF420	5327.0
AGO3	5309.0
PIP4P1	5307.0
NABP2	5282.0
DDIT3	5272.0
GTF2H1	5260.0
CDC40	5251.0
PPARG	5229.0
RUNX3	5211.0
RTF1	5203.0
CDK1	5183.0
COX4I1	5182.0
LDB1	5174.0
ING2	5169.0
SEM1	5154.0
ESR1	5133.0
LEF1	5095.0
SNAPC1	5086.0
CDK13	5083.0
NELFCD	5075.0
INTS8	5063.0
PIN1	5059.0
SP1	5058.0
NRBP1	5018.0
SCO1	5014.0
ZNF430	4992.0
ZNF133	4984.0
CAMK2D	4925.0
AGO4	4905.0
NELFE	4897.0
AUTS2	4888.0
ZNF614	4863.0
PSMC2	4855.0
SNRPD3	4852.0
ZNF747	4844.0
ZFP90	4831.0
GPRIN1	4780.0
GAD2	4766.0
INTS6	4748.0
ELOA2	4740.0
MIR27A	4719.0
NR2C1	4707.0
PRKAA1	4702.0
SST	4646.0
TRIM63	4640.0
ZNF136	4635.0
PSMA1	4619.0
GPX2	4617.0
ZNF607	4587.0
CCNB1	4572.0
ZNF684	4555.0
CCNA1	4534.0
PRMT5	4529.0
NKX2-5	4525.0
TFAP2A	4496.0
HDAC11	4493.0
ZNF793	4490.0
MLH1	4488.0
TAF4B	4482.0
ZNF250	4475.0
KMT2A	4467.0
PSMB9	4456.0
CCNT1	4452.0
SRSF2	4444.0
THRB	4434.0
ZNF37A	4424.0
IFNG	4419.0
CPSF1	4385.0
ZNF441	4384.0
TMEM219	4359.0
YWHAH	4351.0
H2AX	4347.0
ZNF709	4331.0
COX11	4320.0
PDPK1	4310.0
NKX3-2	4308.0
H3C11	4283.0
SESN2	4278.0
RFFL	4277.0
COX18	4252.0
DLL1	4244.0
SMAD2	4243.0
ZFP28	4228.0
TAL1	4197.0
ZNF700	4193.0
INTS14	4176.0
CNOT6	4162.0
ZNF426	4150.0
COL1A2	4140.0
KRBOX5	4127.0
ZNF561	4121.0
MED16	4114.0
POLR2B	4109.0
MEN1	4097.0
E2F5	4087.0
SRSF4	4075.0
DYRK2	4071.0
UBE2D3	4063.0
CSTF2T	4050.0
BARD1	4048.0
HIPK1	4042.0
ZFP69B	4038.0
NOTCH3	4019.0
ABL1	4013.0
BRPF3	3967.0
NR6A1	3966.0
RBM14	3962.0
GRIA2	3960.0
H3C1	3952.0
ZNF415	3949.0
FANCC	3943.0
NR2C2AP	3924.0
ANAPC16	3918.0
MAPK11	3914.0
PSMB5	3878.0
CALM1	3832.0
PHC2	3828.0
PSMD7	3822.0
CCNG2	3791.0
HAND2	3781.0
ZNF454	3750.0
MAML1	3747.0
H3-3A	3716.0
KRBA1	3713.0
CCNK	3709.0
CNOT11	3707.0
ANAPC1	3703.0
WRN	3702.0
CAV1	3687.0
CASC3	3686.0
BRD2	3678.0
CBX6	3657.0
ANAPC7	3650.0
TP53BP2	3634.0
RAD1	3602.0
RORA	3590.0
ZNF777	3562.0
TCEA1	3532.0
TP53RK	3517.0
ZNF775	3515.0
ITCH	3506.0
PCGF2	3438.0
STAT1	3435.0
SUPT16H	3429.0
POU4F1	3404.0
NAMPT	3388.0
CDC26	3378.0
ZNF555	3373.0
FANCD2	3349.0
GATAD2B	3344.0
H3-3B	3343.0
MED13	3320.0
JUNB	3279.0
BRPF1	3271.0
NR5A2	3260.0
ZNF263	3246.0
E2F7	3238.0
ZNF311	3217.0
ZNF547	3214.0
SUPT4H1	3207.0
RNU11	3177.0
BNIP3L	3151.0
KCNIP3	3149.0
ZNF564	3142.0
ZNF460	3110.0
TAF10	3107.0
DGCR8	3099.0
COX7C	3091.0
CDC23	3069.0
ZNF714	3058.0
RBM8A	3055.0
POLR2I	3030.0
CR1	3029.0
TOPBP1	3028.0
HEY2	3023.0
SMARCD1	2983.0
ZNF689	2979.0
ZNF587	2972.0
ZNF70	2963.0
MED6	2948.0
CSNK2B	2924.0
ZNF688	2920.0
CASP2	2908.0
MED15	2904.0
NR5A1	2894.0
H3C10	2893.0
ZNF77	2882.0
ZNF655	2878.0
ZKSCAN5	2849.0
CDC73	2826.0
ZNF470	2813.0
NCBP2	2801.0
RAD9A	2761.0
ATF2	2758.0
OPRK1	2742.0
ZNF443	2727.0
LAMTOR3	2718.0
SKP2	2695.0
INTS3	2657.0
PLXNA4	2629.0
ZNF778	2612.0
MOV10	2578.0
H4C13	2565.0
ZNF445	2554.0
KAT5	2550.0
RBBP8	2549.0
CNOT9	2535.0
SMARCC2	2504.0
RPA1	2497.0
ZNF560	2495.0
SATB2	2492.0
ATM	2488.0
ANAPC15	2482.0
SRSF5	2449.0
ZNF782	2421.0
SSU72	2419.0
GSR	2381.0
ZNF23	2359.0
ZNF18	2357.0
HUS1	2342.0
NR1I2	2340.0
PML	2336.0
TAF6	2335.0
ZNF567	2317.0
ZNF343	2314.0
ZNF99	2310.0
ELOA	2286.0
TP53I3	2281.0
PAX5	2266.0
NFYB	2255.0
TFAP2B	2232.0
PPM1A	2231.0
MED26	2192.0
ZNF727	2182.0
RRAGC	2179.0
PSMB4	2167.0
MEF2C	2135.0
ZNF75A	2133.0
PPP2R5C	2132.0
HDAC9	2121.0
PSMD1	2120.0
PSMA2	2110.0
PCGF5	2047.0
JAG1	2011.0
GTF2A2	2007.0
LBR	1979.0
SOCS3	1947.0
NR1H3	1940.0
MIR24-2	1917.0
CTR9	1916.0
UBE2C	1912.0
HES1	1909.0
ELF1	1902.0
TEAD1	1896.0
ZNF568	1887.0
E2F6	1884.0
TIGAR	1869.0
SUPT5H	1840.0
TXNIP	1827.0
ZNF616	1810.0
ZNF492	1802.0
JUN	1798.0
SRF	1790.0
MRE11	1782.0
FOXO3	1738.0
ZNF558	1734.0
LEO1	1724.0
SIN3A	1712.0
MAGOH	1707.0
PINK1	1683.0
ZSCAN32	1657.0
SRSF6	1601.0
L3MBTL2	1600.0
ZNF226	1599.0
POU2F1	1588.0
GTF2F1	1584.0
ZNF668	1526.0
RMI1	1516.0
TBL1XR1	1474.0
MET	1436.0
SMAD4	1428.0
TXN	1413.0
CNOT2	1408.0
MDC1	1402.0
ARID1A	1347.0
MNAT1	1338.0
RFC3	1337.0
ZNF764	1328.0
MAGOHB	1316.0
HNF4G	1285.0
GTF2H5	1284.0
RFC5	1281.0
PSMD8	1241.0
CASP1	1239.0
ZNF208	1212.0
PLK2	1140.0
ZNF20	1136.0
MED10	1112.0
PSME2	1076.0
ZNF665	1055.0
IL3	1053.0
USP2	1038.0
PPP2R1A	1037.0
CUL1	1033.0
SETD9	993.0
PTEN	982.0
CSTF1	973.0
TCF7L2	896.0
ZNF658	863.0
PITX2	845.0
SNRPF	831.0
RHNO1	826.0
NCBP1	823.0
CNOT3	819.0
JMY	800.0
ZNF771	798.0
CREB1	796.0
AGO2	783.0
NRBF2	769.0
PRDM1	759.0
ZNF716	758.0
CCND2	748.0
CDK2	744.0
GSK3B	734.0
ZNF398	730.0
COX5A	695.0
UBE2I	644.0
POLR2G	642.0
FZR1	635.0
MDM4	628.0
CHD4	626.0
ZNF549	611.0
H4C1	603.0
TNRC6A	595.0
CHEK1	577.0
TCF7L1	561.0
ZNF419	548.0
ZNF691	529.0
TACO1	523.0
SOCS4	497.0
ZNF571	477.0
IQSEC3	461.0
CCNA2	451.0
CHD3	432.0
DAXX	423.0
ZNF707	407.0
H2AC4	375.0
ZNF436	357.0
BID	334.0
ZNF595	322.0
ZNF660	321.0
CCNC	300.0
TFAP2C	294.0
H2BC5	293.0
POLR2F	290.0
ZNF773	282.0
USP7	260.0
CNOT10	259.0
ZNF804B	239.0
CPSF7	226.0
RAD51D	171.0
CSNK2A2	162.0
MBD3	142.0
PCBP4	133.0
SIRT1	128.0
ZFP30	82.0
ZIM3	62.0
ZNF324	53.0
PABPN1	42.0
H4C6	33.0
NOTCH4	21.0
H2BC12	15.0
ZNF496	14.0
TP63	5.0
WWOX	-21.0
ZNF160	-28.0
RBBP4	-35.0
AFF4	-44.0
LAMTOR4	-49.0
BLK	-53.0
SKI	-68.0
ZNF540	-71.0
CDK5	-81.0
RXRG	-86.0
CBFB	-89.0
PRKAG2	-114.0
DHX38	-149.0
NR2E3	-182.0
ACTL6A	-184.0
YY1	-223.0
ZNF483	-229.0
SNAPC2	-251.0
GAD1	-266.0
VDR	-267.0
TNFRSF18	-270.0
CRADD	-302.0
ELL	-305.0
PGR	-310.0
SLC2A3	-337.0
NDRG1	-338.0
ACTL6B	-343.0
SMAD3	-356.0
LRPPRC	-365.0
PRKACA	-398.0
TXNRD1	-403.0
CDC16	-418.0
INTS10	-430.0
ZNF510	-498.0
THOC7	-521.0
CSF1R	-525.0
ZNF500	-526.0
YBX1	-530.0
SGK1	-538.0
APOE	-554.0
ANAPC10	-565.0
ZNF74	-585.0
CNOT6L	-604.0
CDK8	-643.0
RRM2B	-646.0
WDR33	-651.0
BTG2	-667.0
AKT3	-693.0
EAF1	-697.0
NCOR1	-716.0
PPP2CA	-731.0
PPM1D	-735.0
BANP	-747.0
ZNF704	-748.0
ZNF550	-765.0
NR4A1	-768.0
ZNF718	-789.0
PHC1	-801.0
MAPKAPK5	-859.0
PTPN4	-890.0
PSMD3	-900.0
TOP3A	-920.0
ZNF599	-930.0
BCL6	-947.0
CDC27	-960.0
CDK4	-965.0
MED25	-1008.0
ARID1B	-1011.0
MDM2	-1041.0
PLAGL1	-1058.0
CAMK2G	-1086.0
CCNT2	-1096.0
ZNF786	-1101.0
TAF3	-1104.0
HDAC5	-1115.0
CCND3	-1119.0
CLP1	-1131.0
SLC38A9	-1145.0
ANAPC4	-1152.0
LMO2	-1157.0
MAML3	-1158.0
ERCC3	-1166.0
ELOC	-1192.0
CGA	-1206.0
TGFB1	-1214.0
YAP1	-1223.0
ZNF627	-1237.0
CBX4	-1276.0
FURIN	-1279.0
ELF2	-1284.0
ZNF202	-1286.0
ZNF416	-1289.0
VEGFA	-1295.0
RUNX1	-1307.0
RET	-1310.0
ZNF584	-1403.0
ARID2	-1428.0
ITGA5	-1441.0
NR1D2	-1448.0
CDK6	-1449.0
PSMD14	-1456.0
ATXN3	-1477.0
RUNX2	-1490.0
HIPK2	-1495.0
CREBBP	-1522.0
SOD2	-1527.0
GCK	-1570.0
ZNF383	-1575.0
RNU4ATAC	-1593.0
NR1H2	-1598.0
STK11	-1604.0
PSMD6	-1616.0
BLM	-1633.0
G6PC1	-1673.0
PRKAG3	-1678.0
CAMK2B	-1679.0
CPSF6	-1698.0
ATR	-1744.0
TP53INP1	-1761.0
ZNF696	-1763.0
AURKA	-1782.0
PRELID3A	-1798.0
ZNF573	-1801.0
CNOT8	-1806.0
GTF2E2	-1826.0
CTNNB1	-1832.0
CSNK2A1	-1847.0
PSMC4	-1875.0
SMYD2	-1881.0
PCNA	-1901.0
SMARCD3	-1908.0
YWHAQ	-1911.0
H4C2	-1930.0
KAT6A	-1957.0
APAF1	-1971.0
MED23	-1972.0
YEATS4	-1999.0
ZNF613	-2044.0
ZNF225	-2058.0
HDAC2	-2069.0
ZNF180	-2089.0
STEAP3	-2100.0
NPM1	-2118.0
PRMT1	-2125.0
MGA	-2135.0
RNGTT	-2151.0
ZNF563	-2163.0
ASH2L	-2171.0
L3MBTL1	-2195.0
PSMD9	-2211.0
ZNF300	-2234.0
ZNF546	-2243.0
PPARD	-2246.0
VENTX	-2253.0
ZNF354B	-2278.0
PPARA	-2290.0
MSH2	-2317.0
ZNF641	-2325.0
NFKB1	-2329.0
SNRPB	-2336.0
ZNF114	-2359.0
YWHAE	-2361.0
ZNF750	-2392.0
WDR5	-2418.0
SRSF11	-2435.0
THOC6	-2453.0
HDAC4	-2473.0
SYMPK	-2478.0
ZNF100	-2482.0
IL2RA	-2485.0
ZNF517	-2511.0
H2BC13	-2522.0
CENPJ	-2554.0
PLK3	-2568.0
MTOR	-2569.0
NR4A3	-2600.0
ZNF135	-2602.0
UBE2D1	-2611.0
FBXW7	-2633.0
ZNF493	-2639.0
E2F1	-2651.0
E2F4	-2697.0
PIP4K2B	-2718.0
PARP1	-2723.0
COX19	-2736.0
GLS	-2752.0
ZNF222	-2756.0
CEBPB	-2779.0
AKT1	-2798.0
RNF111	-2816.0
OCLN	-2830.0
CNOT1	-2855.0
POLR2A	-2921.0
ITGAL	-2932.0
PIP4K2A	-2961.0
ZNF28	-2963.0
SMAD7	-2979.0
ANAPC5	-2995.0
CPSF4	-2999.0
RFC2	-3031.0
NOTCH2	-3046.0
INTS9	-3071.0
SPI1	-3088.0
RARG	-3093.0
RPRD2	-3101.0
NR3C1	-3105.0
ZNF431	-3113.0
RPRD1A	-3122.0
MTA2	-3127.0
MAX	-3195.0
U2AF2	-3209.0
AIFM2	-3249.0
YES1	-3259.0
ZNF589	-3279.0
NPY	-3282.0
ZC3H8	-3285.0
TNRC6B	-3287.0
MLLT3	-3302.0
PRKCQ	-3312.0
EHMT1	-3330.0
COX16	-3336.0
NOC2L	-3344.0
NUAK1	-3357.0
AURKB	-3362.0
ZNF256	-3369.0
ZNF143	-3376.0
RBL1	-3378.0
CTSL	-3381.0
KMT2E	-3394.0
MAML2	-3395.0
ZNF839	-3397.0
BGLAP	-3417.0
NABP1	-3459.0
ZNF485	-3481.0
ZNF726	-3488.0
NR1H4	-3489.0
GTF2F2	-3493.0
NBN	-3504.0
TAF1L	-3518.0
EP300	-3520.0
ZNF394	-3523.0
RNPS1	-3555.0
AXIN1	-3576.0
CDK12	-3654.0
NOTCH1	-3655.0
ZNF701	-3663.0
MAPK1	-3684.0
ZNF544	-3703.0
CAMK2A	-3709.0
NR2C2	-3729.0
EHMT2	-3734.0
CSF2	-3740.0
ZNF772	-3759.0
MAPK3	-3768.0
CCND1	-3778.0
ZNF184	-3807.0
STUB1	-3810.0
PSMC1	-3824.0
KCTD6	-3841.0
UBC	-3854.0
YAF2	-3869.0
NOP2	-3872.0
ZNF697	-3893.0
BBC3	-3908.0
PRKAB1	-3933.0
CTDP1	-3934.0
WWP1	-3989.0
ZNF350	-4011.0
SNAPC3	-4024.0
PVALB	-4053.0
ZKSCAN8	-4076.0
ZC3H11A	-4100.0
COX14	-4123.0
TAF4	-4125.0
ZFPM1	-4145.0
ZNF212	-4153.0
DEK	-4179.0
TP73	-4189.0
NFYC	-4190.0
SURF1	-4207.0
PMS2	-4215.0
ZNF429	-4226.0
SCO2	-4239.0
SUMO1	-4240.0
RPTOR	-4249.0
FANCI	-4253.0
RICTOR	-4281.0
ZNF433	-4298.0
UBE2E1	-4365.0
LSM10	-4373.0
GATA3	-4387.0
CDC7	-4394.0
MYB	-4398.0
NELFA	-4425.0
THOC1	-4445.0
ZNF605	-4448.0
NR2F6	-4459.0
E2F8	-4466.0
SMURF2	-4508.0
CCNH	-4515.0
PSMB6	-4529.0
PRKCB	-4534.0
CASP6	-4541.0
CCNE1	-4557.0
ZNF266	-4558.0
NR2F1	-4573.0
KDM5B	-4585.0
TRIM33	-4586.0
EED	-4609.0
SETD1B	-4620.0
GATAD2A	-4623.0
FYTTD1	-4628.0
SMARCA2	-4633.0
HIVEP3	-4638.0
TGIF1	-4696.0
ZKSCAN3	-4731.0
NLRC4	-4751.0
TSC2	-4803.0
PSMD11	-4817.0
H2BC17	-4820.0
NR1D1	-4827.0
PRELID1	-4839.0
PPP2CB	-4856.0
EIF4A3	-4880.0
DDB2	-4886.0
ZFP69	-4898.0
ALYREF	-4908.0
RABGGTA	-4943.0
MED27	-4976.0
RXRB	-4992.0
BRCA1	-5013.0
KMT2C	-5024.0
MED30	-5033.0
GAMT	-5056.0
IHH	-5064.0
THBS1	-5066.0
TFDP2	-5068.0
TCF3	-5077.0
ZNF257	-5078.0
KAT2A	-5086.0
PHF20	-5094.0
ZNF737	-5103.0
HDAC3	-5138.0
TPX2	-5169.0
TFDP1	-5182.0
ANAPC2	-5233.0
ZNF724	-5253.0
CNOT4	-5256.0
PRDX1	-5269.0
PPP1R13B	-5273.0
CBX5	-5278.0
CCNE2	-5320.0
INTS1	-5328.0
PPARGC1B	-5342.0
CTSV	-5343.0
SOX9	-5347.0
RPRD1B	-5368.0
MAPKAP1	-5374.0
HTT	-5409.0
AGO1	-5438.0
BAX	-5489.0
SMARCA4	-5508.0
SMARCB1	-5531.0
AKT2	-5544.0
ZNF425	-5547.0
TP53	-5554.0
ANAPC11	-5598.0
BMAL1	-5603.0
SNRPE	-5663.0
SKIL	-5727.0
RYBP	-5731.0
PBRM1	-5746.0
CPSF3	-5756.0
PRKAG1	-5759.0
ERCC2	-5812.0
TNFRSF10B	-5846.0
ZNF333	-5851.0
ZNF514	-5919.0
NCOR2	-6028.0
PSMB7	-6036.0
ZNF692	-6048.0
ZNF331	-6059.0
RRAGA	-6085.0
TAF2	-6099.0
ZNF521	-6111.0
PSMD5	-6141.0
ZNF3	-6150.0
MED31	-6155.0
ZNF169	-6166.0
ZNF92	-6169.0
TRIM28	-6208.0
RRM2	-6248.0
HDAC10	-6257.0
NFATC2	-6265.0
RPA3	-6270.0
ZNF552	-6278.0
PRDM7	-6286.0
PTPN1	-6302.0
KAT2B	-6305.0
SMURF1	-6309.0
YWHAG	-6321.0
MED7	-6342.0
RXRA	-6343.0
ARID3A	-6357.0
SSRP1	-6361.0
TNRC6C	-6374.0
TCF12	-6379.0
CDKN2B	-6400.0
THRA	-6419.0
ZNF71	-6420.0
PCGF6	-6451.0
ZNF506	-6483.0
NPAS4	-6491.0
SETD1A	-6496.0
DNA2	-6525.0
PSME3	-6565.0
IL6	-6578.0
GTF2H4	-6593.0
ZNF138	-6601.0
MYL9	-6609.0
MMP13	-6618.0
INTS11	-6634.0
MLLT1	-6639.0
RING1	-6649.0
RB1	-6661.0
INTS13	-6668.0
LGALS3	-6679.0
SREBF1	-6687.0
NR0B2	-6748.0
PRDX2	-6750.0
ZNF213	-6803.0
H4C4	-6811.0
ERBB2	-6841.0
ZNF543	-6853.0
CCNG1	-6874.0
KMT5A	-6918.0
ZFP14	-6942.0
PSMC6	-6973.0
POU2F2	-7010.0
ZNF530	-7014.0
BRD7	-7024.0
TEAD2	-7075.0
MLST8	-7168.0
ZNF175	-7229.0
ZNF596	-7232.0
CCN2	-7242.0
H2BC1	-7243.0
SCMH1	-7282.0
H2BC3	-7283.0
ZNF738	-7307.0
ZNF611	-7320.0
ING5	-7326.0
ZNF302	-7395.0
BMI1	-7402.0
PSMA8	-7408.0
TNFRSF10C	-7451.0
ZNF554	-7520.0
BCL2L14	-7552.0
ZNF597	-7575.0
RNMT	-7596.0
ITGA2B	-7597.0
MED24	-7612.0
CAT	-7661.0
NFE2	-7663.0
ZNF551	-7679.0
MIR137	-7743.0
H4C11	-7768.0
H2BC6	-7780.0
CASP10	-7792.0
ZNF662	-7807.0
PPP2R1B	-7864.0
ZNF385A	-7881.0
TRPC3	-7899.0
TAF8	-7906.0
ZNF324B	-7921.0
CRH	-7939.0
CDKN1A	-7949.0
UBE2S	-7971.0
THOC3	-8002.0
FOXO1	-8010.0
CARM1	-8030.0
MSTN	-8033.0
ZNF200	-8050.0
ZNF282	-8067.0
ZNF254	-8073.0
PRR5	-8081.0
ZNF418	-8153.0
KMT2D	-8184.0
SLBP	-8246.0
ZNF860	-8275.0
RARA	-8279.0
MIR24-1	-8336.0
ZNF33B	-8360.0
POLR2C	-8417.0
SRC	-8426.0
CBX2	-8434.0
ZNF432	-8446.0
ZNF45	-8456.0
HDAC7	-8509.0
CGB8	-8530.0
ZNF205	-8554.0
TGIF2	-8576.0
AGRP	-8598.0
ZNF675	-8691.0
TEAD3	-8695.0
ZNF626	-8699.0
TFAP2E	-8764.0
NPPA	-8794.0
TNKS1BP1	-8797.0
DDX39B	-8827.0
CLDN5	-8829.0
SP7	-8851.0
LSM11	-8860.0
CTSK	-8866.0
INS	-8871.0
ZNF710	-8874.0
ZNF619	-8880.0
PMAIP1	-8908.0
SLU7	-8919.0
KMT2B	-8932.0
ZNF417	-8956.0
ZNF679	-8958.0
ZNF124	-8963.0
CITED4	-9035.0
ATRIP	-9069.0
ZNF287	-9088.0
ZNF562	-9107.0
RORC	-9137.0
MYBL2	-9142.0
BIRC5	-9189.0
H3C6	-9199.0
PIDD1	-9208.0
UCMA	-9447.0
ZNF320	-9457.0
ZNF519	-9489.0
CGB5	-9509.0
ZNF761	-9672.0
POLR2J	-9831.0
ZNF732	-9854.0

---

REACTOME_CELLULAR_RESPONSE_TO_STARVATION

REACTOME_CELLULAR_RESPONSE_TO_STARVATION

	1582
set	REACTOME_CELLULAR_RESPONSE_TO_STARVATION
setSize	147
pANOVA	0.000155
s.dist	0.181
p.adjustANOVA	0.0087

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL10L	11612
LAMTOR5	11079
FAU	10809
ATP6V1E2	10806
RPS3	10729
ATP6V1G1	10701
RPL10A	10664
RPS11	10587
SH3BP4	10368
FNIP1	10236
RPL37A	10142
RPS15A	10069
RPS27	9839
RPL30	9827
RPL38	9821
RPS28	9794
RPLP1	9720
RPL27	9441
NPRL2	9343
RPL22L1	9297

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL10L	11612.0
LAMTOR5	11079.0
FAU	10809.0
ATP6V1E2	10806.0
RPS3	10729.0
ATP6V1G1	10701.0
RPL10A	10664.0
RPS11	10587.0
SH3BP4	10368.0
FNIP1	10236.0
RPL37A	10142.0
RPS15A	10069.0
RPS27	9839.0
RPL30	9827.0
RPL38	9821.0
RPS28	9794.0
RPLP1	9720.0
RPL27	9441.0
NPRL2	9343.0
RPL22L1	9297.0
RPS5	9280.0
RPLP0	9243.0
RPL15	9182.0
LAMTOR1	9143.0
RPL12	9097.0
RPL13A	8817.5
RPS27L	8690.0
ATP6V1B2	8677.0
RPL13	8465.0
RPL26	8334.0
RPS9	8300.0
RPL36AL	8178.5
RPL9	8114.0
RPS27A	8106.0
RPS6	8097.0
RPL35	8050.0
RPL27A	7990.0
EIF2S1	7914.0
SESN1	7754.0
RPS16	7626.0
RPS15	7463.0
RPS24	7430.0
CEBPG	7348.0
RPS10	7327.0
RPL34	7322.0
RPL7	7281.0
RPL23	7239.0
ATP6V1G2	6996.0
RPL6	6769.0
RPL17	6670.0
RPL7A	6664.0
RPL18A	6615.0
RPL5	6595.0
ATF3	6452.0
ATP6V1H	6437.0
RPL41	6359.0
RPL8	6213.0
LAMTOR2	6067.0
RHEB	6060.0
RPS3A	6057.0
RPL23A	5805.0
RPS18	5767.0
RPS14	5716.0
RRAGD	5685.0
UBA52	5407.0
DDIT3	5272.0
ATP6V0D2	5161.0
RPL26L1	5040.0
WDR24	4527.0
SESN2	4278.0
RPL31	4100.0
KPTN	3757.0
IMPACT	3548.0
ITFG2	3401.0
RPL24	3372.0
RPL14	3033.0
ATP6V0D1	2989.0
ATF2	2758.0
LAMTOR3	2718.0
RPS7	2583.0
RPL29	2563.0
RPL4	2539.0
RRAGC	2179.0
ATF4	2108.0
RPL11	1986.0
RPS29	1784.0
ATP6V1D	1690.0
ATP6V1E1	1670.0
BMT2	1238.0
RPL3	1194.0
MIOS	1130.0
RPS26	1092.0
ASNS	1039.0
RPLP2	844.0
RPS8	808.0
RPL37	742.0
SZT2	479.0
RPL28	382.0
SEH1L	380.0
RPS25	379.0
RPL21	189.0
RPS21	153.0
LAMTOR4	-49.0
RPL35A	-148.0
RPL19	-158.0
ATP6V1C2	-264.0
ATP6V1F	-642.0
RPS13	-895.0
RPS12	-1124.0
RPS23	-1129.0
SLC38A9	-1145.0
ATP6V1A	-1298.0
RPL18	-1323.0
FNIP2	-2141.0
RPS20	-2282.0
TRIB3	-2295.0
ATP6V0E1	-2493.0
MTOR	-2569.0
EIF2AK4	-2637.0
CEBPB	-2779.0
ATP6V1C1	-2869.0
RPSA	-2910.0
RPL39L	-3199.0
WDR59	-3611.0
RPL36	-3656.0
RPL32	-4143.0
TCIRG1	-4247.0
RPTOR	-4249.0
KICS2	-4252.0
ATP6V0C	-4771.0
NPRL3	-5050.0
GCN1	-5173.0
EIF2S2	-5373.0
FLCN	-5685.0
RPS2	-6039.0
RRAGA	-6085.0
ATP6V0B	-6214.0
CASTOR1	-6411.0
SEC13	-6884.0
RPS19	-6970.0
MLST8	-7168.0
DEPDC5	-7368.0
ATP6V0E2	-8086.0
RPL22	-8308.0
ATP6V1B1	-8390.0
ATP6V1G3	-8666.0
RPL3L	-8798.0

---

REACTOME_DISEASES_OF_PROGRAMMED_CELL_DEATH

REACTOME_DISEASES_OF_PROGRAMMED_CELL_DEATH

	1502
set	REACTOME_DISEASES_OF_PROGRAMMED_CELL_DEATH
setSize	96
pANOVA	0.000158
s.dist	0.223
p.adjustANOVA	0.0087

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FASLG	11647.0
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
CAPNS2	11107.0
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
APP	10273.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
H3C8	9291.0
H2BC10	9197.0
H2AC7	8965.5

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FASLG	11647.0
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
CAPNS2	11107.0
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
APP	10273.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
H3C8	9291.0
H2BC10	9197.0
H2AC7	8965.5
H2BC7	8965.5
H3C12	8767.0
MLKL	8576.0
H2AC8	8539.0
GOLGA2	8407.0
C1QBP	8314.0
TRAF2	8299.0
H3C3	8281.0
H2BC11	8255.0
CDKN2A	7994.0
H2AZ1	7981.0
H2AC20	7915.0
H4C8	7890.0
BCL2L11	7888.0
H4C12	7649.0
H4C3	7349.0
H4C9	7126.0
CASP8	7115.0
CDK5R1	6726.0
CDC25B	6694.0
H2BC8	6516.0
EZH2	6449.0
H2AJ	6389.0
SUZ12	6038.0
CDC25C	5843.0
H2AZ2	5736.0
H4C5	5555.0
H2AX	4347.0
H3C11	4283.0
DNMT1	3953.0
H3C1	3952.0
CAPN1	3898.0
H3-3A	3716.0
POLA2	3536.0
H3-3B	3343.0
H3C10	2893.0
H4C13	2565.0
PRIM1	2503.0
JUN	1798.0
FOXO3	1738.0
H4C1	603.0
CAST	573.0
H2AC4	375.0
H2BC5	293.0
H4C6	33.0
H2BC12	15.0
RBBP4	-35.0
RIPK1	-48.0
CDK5	-81.0
GSDME	-286.0
LMNB1	-941.0
PRIM2	-1328.0
SOD2	-1527.0
H4C2	-1930.0
DNMT3B	-2063.0
TRADD	-2101.0
RIPK3	-2126.0
YWHAE	-2361.0
H2BC13	-2522.0
CDC25A	-2985.0
CAPN2	-3830.0
EED	-4609.0
H2BC17	-4820.0
DNMT3A	-5036.0
PRDX1	-5269.0
TP53	-5554.0
FADD	-5814.0
CAPNS1	-6338.0
PRDX2	-6750.0
H4C4	-6811.0
LMNA	-6893.0
H2BC1	-7243.0
H2BC3	-7283.0
H4C11	-7768.0
H2BC6	-7780.0
H3C6	-9199.0

---

REACTOME_AQUAPORIN_MEDIATED_TRANSPORT

REACTOME_AQUAPORIN_MEDIATED_TRANSPORT

	781
set	REACTOME_AQUAPORIN_MEDIATED_TRANSPORT
setSize	51
pANOVA	0.000159
s.dist	-0.306
p.adjustANOVA	0.0087

Top enriched genes

Top 20 genes

GeneID	Gene Rank
AQP7	-9890
AQP12A	-9800
GNG8	-9714
AVP	-9573
AQP2	-9209
GNGT1	-9205
AQP5	-8811
AQP3	-8198
AQP1	-8101
GNG2	-7918
AQP8	-7879
AQP10	-7820
AQP6	-6813
ADCY7	-6683
ADCY3	-6497
MIP	-6381
RAB11FIP2	-6062
PRKAR1A	-5587
ADCY9	-5146
GNG12	-4444

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
AQP7	-9890
AQP12A	-9800
GNG8	-9714
AVP	-9573
AQP2	-9209
GNGT1	-9205
AQP5	-8811
AQP3	-8198
AQP1	-8101
GNG2	-7918
AQP8	-7879
AQP10	-7820
AQP6	-6813
ADCY7	-6683
ADCY3	-6497
MIP	-6381
RAB11FIP2	-6062
PRKAR1A	-5587
ADCY9	-5146
GNG12	-4444
GNAS	-4327
PRKAR1B	-4026
RAB11A	-3906
GNB5	-3454
GNG7	-3373
PRKACG	-3257
GNB4	-3106
PRKAR2A	-3061
ADCY5	-2161
GNG4	-1988
GNB1	-1458
ADCY4	-1408
GNB2	-494
PRKACB	-414
PRKACA	-398
ADCY6	-234
GNB3	213
GNG3	739
AQP9	1304
PRKAR2B	1942
AQP4	1981
GNG13	2486
GNG5	3178
AQP11	3434
GNG11	5544
ADCY1	5621
MYO5B	7261
ADCY8	7685
ADCY2	8285
GNG10	10645
GNGT2	11574

---

REACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT

REACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT

	379
set	REACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT
setSize	222
pANOVA	0.000209
s.dist	0.144
p.adjustANOVA	0.0111

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC6	11639.0
RBBP5	11312.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
WNT8A	10773.0
PSMB10	10756.0
PSMB11	10643.0
H2AC14	10639.0
PSMD2	10583.0
RSPO4	10560.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
PSMB3	10477.0
FZD5	10472.0
H3C4	10448.0
H2BC26	10335.0
H4C16	10207.0
PSMA3	10095.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC6	11639.0
RBBP5	11312.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
WNT8A	10773.0
PSMB10	10756.0
PSMB11	10643.0
H2AC14	10639.0
PSMD2	10583.0
RSPO4	10560.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
PSMB3	10477.0
FZD5	10472.0
H3C4	10448.0
H2BC26	10335.0
H4C16	10207.0
PSMA3	10095.0
H2BC21	10024.0
DKK2	10023.0
H3C2	10000.0
PSMD13	9995.0
H2BC15	9893.0
PSMA4	9855.0
MYC	9848.0
SOX2	9810.0
PSMB1	9750.0
YWHAZ	9682.0
FZD8	9674.0
SFRP1	9529.0
PSMF1	9417.0
PSME1	9374.0
H3C8	9291.0
H2BC10	9197.0
AXIN2	9107.0
H2AC7	8965.5
H2BC7	8965.5
PSMA6	8867.0
H3C12	8767.0
PSMA5	8596.0
H2AC8	8539.0
SOX17	8368.0
RSPO2	8283.0
H3C3	8281.0
H2BC11	8255.0
PSMC5	8218.0
RPS27A	8106.0
LGR5	8105.0
PIP5K1B	8082.0
RBX1	8051.0
H2AZ1	7981.0
H2AC20	7915.0
H4C8	7890.0
PSMD12	7877.0
RSPO3	7846.0
UBB	7699.0
H4C12	7649.0
RSPO1	7584.0
PYGO2	7568.0
PSMA7	7538.0
PSMD4	7467.0
H4C3	7349.0
H4C9	7126.0
TCF7	7044.0
TNKS	6903.0
WNT3A	6899.0
HDAC1	6863.0
USP8	6846.0
PSME4	6787.0
FZD1	6681.0
H2BC8	6516.0
PSMB8	6451.0
LGR4	6400.0
H2AJ	6389.0
XPO1	6362.0
PSMB2	6330.0
KREMEN1	6313.0
PSMC3	6214.0
DACT1	5933.0
H2AZ2	5736.0
H4C5	5555.0
UBA52	5407.0
PPP2R5A	5253.0
RUNX3	5211.0
FZD4	5202.0
SEM1	5154.0
LEF1	5095.0
DKK1	5074.0
PPP2R5E	5061.0
CHD8	4960.0
FRAT2	4942.0
PSMC2	4855.0
TLE4	4839.0
PSMA1	4619.0
TCF4	4536.0
WNT5A	4504.0
PSMB9	4456.0
H2AX	4347.0
SOX4	4301.0
H3C11	4283.0
WNT1	4120.0
MEN1	4097.0
HECW1	4061.0
H3C1	3952.0
PSMB5	3878.0
PSMD7	3822.0
H3-3A	3716.0
CAV1	3687.0
DVL2	3530.0
H3-3B	3343.0
BCL9	3265.0
FZD2	3179.0
CSNK2B	2924.0
H3C10	2893.0
KREMEN2	2873.0
CDC73	2826.0
H4C13	2565.0
KAT5	2550.0
SOX6	2485.0
PSMB4	2167.0
PPP2R5C	2132.0
PSMD1	2120.0
PSMA2	2110.0
TLE3	1882.0
RUVBL1	1837.0
LEO1	1724.0
LRP5	1546.0
TERT	1523.0
PSMD8	1241.0
PPP2R5B	1196.0
PSME2	1076.0
PPP2R1A	1037.0
APC	956.0
TCF7L2	896.0
CXXC4	858.0
GSK3B	734.0
FRAT1	652.0
H4C1	603.0
TCF7L1	561.0
H2AC4	375.0
H2BC5	293.0
WNT8B	238.0
CSNK2A2	162.0
CSNK1G2	111.0
H4C6	33.0
H2BC12	15.0
DVL1	-9.0
FZD6	-45.0
PYGO1	-625.0
PPP2CA	-731.0
SOX7	-777.0
RNF146	-833.0
PSMD3	-900.0
WNT9A	-992.0
CSNK1A1	-1116.0
RNF43	-1292.0
PSMD14	-1456.0
CREBBP	-1522.0
PSMD6	-1616.0
USP34	-1711.0
SFRP2	-1807.0
CTNNB1	-1832.0
CSNK2A1	-1847.0
PSMC4	-1875.0
TNKS2	-1890.0
H4C2	-1930.0
LGR6	-2131.0
ASH2L	-2171.0
PSMD9	-2211.0
WNT3	-2221.0
RYK	-2487.0
LRP6	-2514.0
H2BC13	-2522.0
CTNNBIP1	-2535.0
ZNRF3	-2687.0
AKT1	-2798.0
BTRC	-2976.0
EP300	-3520.0
AXIN1	-3576.0
PSMC1	-3824.0
UBC	-3854.0
KLHL12	-3916.0
SMURF2	-4508.0
PSMB6	-4529.0
PPP2R5D	-4601.0
PSMD11	-4817.0
H2BC17	-4820.0
PPP2CB	-4856.0
CUL3	-4950.0
SOX9	-5347.0
TRRAP	-5405.0
CTBP1	-5477.0
SMARCA4	-5508.0
AKT2	-5544.0
CCDC88C	-5757.0
PSMB7	-6036.0
PSMD5	-6141.0
CBY1	-6347.0
DVL3	-6370.0
H3-4	-6526.0
PSME3	-6565.0
H4C4	-6811.0
PSMC6	-6973.0
SOX13	-7221.0
H2BC1	-7243.0
H2BC3	-7283.0
WIF1	-7322.0
PSMA8	-7408.0
H4C11	-7768.0
H2BC6	-7780.0
PPP2R1B	-7864.0
TLE1	-7987.0
TLE2	-8109.0
KMT2D	-8184.0
SOST	-8893.0
WNT4	-9038.0
DKK4	-9094.0
CSNK1E	-9158.0
H3C6	-9199.0
BCL9L	-9852.0

---

REACTOME_THE_CITRIC_ACID_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT

REACTOME_THE_CITRIC_ACID_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT

	104
set	REACTOME_THE_CITRIC_ACID_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT
setSize	159
pANOVA	0.000222
s.dist	0.17
p.adjustANOVA	0.0114

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PDPR	11898
UQCRB	11808
ATP5PO	11189
PDHA2	11133
COX6B1	11101
NDUFA4	10897
ME2	10721
NDUFA8	10698
NDUFB5	10695
ATP5MC1	10565
TIMMDC1	10471
LDHC	10374
ATP5MG	10328
PDHB	10290
NDUFB3	10093
NDUFB1	9888
NDUFA3	9660
NDUFS4	9658
UQCRH	9525
LDHAL6B	9504

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PDPR	11898
UQCRB	11808
ATP5PO	11189
PDHA2	11133
COX6B1	11101
NDUFA4	10897
ME2	10721
NDUFA8	10698
NDUFB5	10695
ATP5MC1	10565
TIMMDC1	10471
LDHC	10374
ATP5MG	10328
PDHB	10290
NDUFB3	10093
NDUFB1	9888
NDUFA3	9660
NDUFS4	9658
UQCRH	9525
LDHAL6B	9504
NDUFA9	9323
NDUFS7	9301
ADHFE1	9249
FAHD1	9202
TMEM126B	9106
COX6A1	9035
NDUFB4	8960
COX8A	8799
ATP5PB	8717
COX7A2L	8528
DLAT	8452
COX20	8391
ETFDH	8303
ATP5PF	8240
NDUFAF4	8230
NDUFV2	8158
NDUFV3	8125
NDUFA6	7985
UQCRC2	7911
NDUFAF7	7910
COX5B	7869
PDK2	7737
NDUFS1	7683
UCP2	7602
UQCR10	7523
VDAC1	7505
ATP5ME	7489
CYCS	7449
NUBPL	7338
HAGH	7262
NDUFS6	7214
LDHA	6735
ATP5F1A	6728
COQ10B	6680
SDHC	6639
FH	6543
ETFB	6380
ATP5F1D	6361
IDH3A	6317
COX6C	6280
NDUFAF1	5927
UQCR11	5771
ATP5MC3	5428
SLC25A27	5364
NDUFB6	5346
NDUFAF2	5206
COX4I1	5182
CS	5110
SCO1	5014
PDK4	4661
L2HGDH	4364
COX11	4320
COX18	4252
MPC2	4204
COQ10A	3899
SUCLA2	3869
ATP5F1B	3853
NDUFS3	3776
SDHB	3538
UQCRC1	3391
PDHX	3229
TMEM186	3170
COX7C	3091
ATP5MC2	2765
ECSIT	2406
NDUFS5	2404
IDH3B	2147
NDUFAF5	1873
NDUFB10	1753
NDUFB7	1649
BSG	1633
SDHD	1509
DMAC2L	1492
NDUFA2	1456
LDHB	1368
ATP5PD	1042
NDUFA12	992
NDUFC1	930
DLST	926
ACO2	852
UCP1	848
NDUFB2	842
NDUFA11	700
COX5A	695
DLD	602
UQCRQ	585
D2HGDH	534
TACO1	523
NDUFAF3	519
NDUFA7	320
MPC1	-99
LRPPRC	-365
ETFA	-426
SLC16A1	-607
NDUFA10	-922
ATP5MF	-1084
SLC16A8	-1176
NDUFC2	-1334
ATP5F1C	-1335
ACAD9	-1350
GLO1	-1644
PPARD	-2246
COA1	-2402
NDUFAF6	-2543
GSTZ1	-2713
NDUFS8	-2728
COX19	-2736
TRAP1	-3017
COX16	-3336
SUCLG1	-3469
MDH2	-3688
OGDH	-3907
COX14	-4123
SURF1	-4207
SCO2	-4239
ME3	-4458
PDP2	-4499
PDK1	-4597
NDUFA13	-4849
NDUFA5	-5034
ME1	-5053
CYC1	-5055
SUCLG2	-5234
NDUFS2	-5361
NDUFB8	-5594
NDUFB9	-5833
PM20D1	-5856
NNT	-6074
PDP1	-6083
SDHA	-6233
RXRA	-6343
LDHAL6A	-6368
ATP5F1E	-6470
UQCRFS1	-6502
IDH2	-6708
SLC16A3	-7209
NDUFAB1	-7763
NDUFV1	-9072
UCP3	-9633

---

REACTOME_POSITIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION

REACTOME_POSITIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION

	851
set	REACTOME_POSITIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION
setSize	98
pANOVA	0.000268
s.dist	0.213
p.adjustANOVA	0.0133

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
POLR2L	10239.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
POLR2K	9561.0
H3C8	9291.0
H2BC10	9197.0
TBP	9059.0
H2AC7	8965.5

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
POLR2L	10239.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
POLR2K	9561.0
H3C8	9291.0
H2BC10	9197.0
TBP	9059.0
H2AC7	8965.5
H2BC7	8965.5
H3C12	8767.0
H2AC8	8539.0
H3C3	8281.0
H2BC11	8255.0
TAF1A	8186.0
SF3B1	8141.0
DDX21	8009.0
H2AZ1	7981.0
POLR1H	7961.0
H2AC20	7915.0
H4C8	7890.0
H4C12	7649.0
H4C3	7349.0
ACTB	7138.0
H4C9	7126.0
TAF1D	6989.0
POLR1C	6895.0
HDAC1	6863.0
CBX3	6759.0
POLR2H	6733.0
POLR1D	6572.0
H2BC8	6516.0
POLR2E	6396.0
H2AJ	6389.0
H2AZ2	5736.0
H4C5	5555.0
TAF1B	5139.0
POLR1F	4789.0
SMARCA5	4771.0
H2AX	4347.0
H3C11	4283.0
H3C1	3952.0
H3-3A	3716.0
GATAD2B	3344.0
H3-3B	3343.0
H3C10	2893.0
H4C13	2565.0
BAZ1B	1630.0
MTA1	738.0
GSK3B	734.0
ERCC6	694.0
CHD4	626.0
H4C1	603.0
POLR1G	474.0
CHD3	432.0
H2AC4	375.0
H2BC5	293.0
POLR2F	290.0
MBD3	142.0
H4C6	33.0
H2BC12	15.0
RBBP4	-35.0
POLR1B	-932.0
POLR1E	-1569.0
H4C2	-1930.0
HDAC2	-2069.0
MYO1C	-2085.0
H2BC13	-2522.0
MTA2	-3127.0
EP300	-3520.0
EHMT2	-3734.0
TTF1	-4061.0
DEK	-4179.0
POLR1A	-4222.0
GATAD2A	-4623.0
H2BC17	-4820.0
KAT2A	-5086.0
KAT2B	-6305.0
H4C4	-6811.0
H2BC1	-7243.0
H2BC3	-7283.0
MTA3	-7287.0
H4C11	-7768.0
H2BC6	-7780.0
MYBBP1A	-8280.0
TAF1C	-8729.0
H3C6	-9199.0

---

REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION

REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION

	437
set	REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION
setSize	138
pANOVA	0.000358
s.dist	0.176
p.adjustANOVA	0.0171

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
POLR2L	10239.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
POLR2K	9561.0
AEBP2	9465.0
SAP18	9299.0
H3C8	9291.0
H2BC10	9197.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
POLR2L	10239.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
POLR2K	9561.0
AEBP2	9465.0
SAP18	9299.0
H3C8	9291.0
H2BC10	9197.0
TBP	9059.0
H2AC7	8965.5
H2BC7	8965.5
H3C12	8767.0
CDK7	8660.0
TET3	8546.0
H2AC8	8539.0
H3C3	8281.0
H2BC11	8255.0
TAF1A	8186.0
SF3B1	8141.0
DDX21	8009.0
H2AZ1	7981.0
POLR1H	7961.0
TDG	7942.0
SIN3B	7929.0
H2AC20	7915.0
H4C8	7890.0
H4C12	7649.0
H4C3	7349.0
GTF2H3	7271.0
SAP30L	7264.0
ACTB	7138.0
H4C9	7126.0
TAF1D	6989.0
POLR1C	6895.0
HDAC1	6863.0
CBX3	6759.0
POLR2H	6733.0
POLR1D	6572.0
H2BC8	6516.0
EZH2	6449.0
POLR2E	6396.0
H2AJ	6389.0
SUZ12	6038.0
ARID4B	5817.0
H2AZ2	5736.0
H4C5	5555.0
GTF2H1	5260.0
TAF1B	5139.0
POLR1F	4789.0
SMARCA5	4771.0
H2AX	4347.0
H3C11	4283.0
PHF19	4265.0
PHF1	4056.0
DNMT1	3953.0
H3C1	3952.0
BAZ2A	3783.0
H3-3A	3716.0
GATAD2B	3344.0
H3-3B	3343.0
MBD2	3169.0
UBTF	3135.0
RRP8	3015.0
H3C10	2893.0
H4C13	2565.0
SIN3A	1712.0
TET1	1687.0
BAZ1B	1630.0
SUDS3	1399.0
MNAT1	1338.0
GTF2H5	1284.0
SAP30BP	746.0
MTA1	738.0
GSK3B	734.0
ERCC6	694.0
CHD4	626.0
H4C1	603.0
POLR1G	474.0
CHD3	432.0
H2AC4	375.0
H2BC5	293.0
POLR2F	290.0
TET2	243.0
MBD3	142.0
SIRT1	128.0
H4C6	33.0
H2BC12	15.0
RBBP4	-35.0
DNMT3L	-78.0
UHRF1	-192.0
POLR1B	-932.0
ERCC3	-1166.0
POLR1E	-1569.0
H4C2	-1930.0
DNMT3B	-2063.0
HDAC2	-2069.0
MYO1C	-2085.0
H2BC13	-2522.0
MTA2	-3127.0
MTF2	-3188.0
EP300	-3520.0
SAP30	-3642.0
EHMT2	-3734.0
TTF1	-4061.0
DEK	-4179.0
POLR1A	-4222.0
JARID2	-4399.0
CCNH	-4515.0
EED	-4609.0
GATAD2A	-4623.0
SAP130	-4769.0
H2BC17	-4820.0
DNMT3A	-5036.0
KAT2A	-5086.0
ERCC2	-5812.0
KAT2B	-6305.0
GTF2H4	-6593.0
H4C4	-6811.0
H2BC1	-7243.0
H2BC3	-7283.0
MTA3	-7287.0
H4C11	-7768.0
H2BC6	-7780.0
MYBBP1A	-8280.0
TAF1C	-8729.0
H3C6	-9199.0

---

REACTOME_INHIBITION_OF_DNA_RECOMBINATION_AT_TELOMERE

REACTOME_INHIBITION_OF_DNA_RECOMBINATION_AT_TELOMERE

	1530
set	REACTOME_INHIBITION_OF_DNA_RECOMBINATION_AT_TELOMERE
setSize	63
pANOVA	0.000364
s.dist	0.26
p.adjustANOVA	0.0171

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H2BC26	10335.0
POLR2L	10239.0
H4C16	10207.0
H2BC21	10024.0
H2BC15	9893.0
POLR2K	9561.0
POLR2D	9276.0
H2BC10	9197.0
H2AC7	8965.5
H2BC7	8965.5
H2AC8	8539.0
H2BC11	8255.0
H2AZ1	7981.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H2BC26	10335.0
POLR2L	10239.0
H4C16	10207.0
H2BC21	10024.0
H2BC15	9893.0
POLR2K	9561.0
POLR2D	9276.0
H2BC10	9197.0
H2AC7	8965.5
H2BC7	8965.5
H2AC8	8539.0
H2BC11	8255.0
H2AZ1	7981.0
H2AC20	7915.0
H4C8	7890.0
H4C12	7649.0
H4C3	7349.0
TERF2IP	7193.0
H4C9	7126.0
ACD	7122.5
POLR2H	6733.0
H2BC8	6516.0
POLR2E	6396.0
H2AJ	6389.0
POT1	5944.0
H2AZ2	5736.0
H4C5	5555.0
TINF2	4455.0
H2AX	4347.0
POLR2B	4109.0
H3-3A	3716.0
H3-3B	3343.0
POLR2I	3030.0
H4C13	2565.0
TERF2	2296.0
POLR2G	642.0
H4C1	603.0
DAXX	423.0
H2AC4	375.0
H2BC5	293.0
POLR2F	290.0
H4C6	33.0
H2BC12	15.0
H4C2	-1930.0
H2BC13	-2522.0
POLR2A	-2921.0
H2BC17	-4820.0
TERF1	-6391.0
H3-4	-6526.0
H4C4	-6811.0
H2BC1	-7243.0
H2BC3	-7283.0
H4C11	-7768.0
H2BC6	-7780.0
POLR2C	-8417.0
POLR2J	-9831.0

---

REACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

REACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

	887
set	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS
setSize	100
pANOVA	0.000403
s.dist	0.205
p.adjustANOVA	0.0179

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
POM121C	10520.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
POLR2L	10239.0
NUP50	10237.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
NUP35	9667.0
POLR2K	9561.0
IPO8	9384.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
POM121C	10520.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
POLR2L	10239.0
NUP50	10237.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
NUP35	9667.0
POLR2K	9561.0
IPO8	9384.0
H3C8	9291.0
POLR2D	9276.0
H2BC10	9197.0
H2AC7	8965.5
H2BC7	8965.5
H3C12	8767.0
NUP42	8689.0
H2AC8	8539.0
H3C3	8281.0
H2BC11	8255.0
H2AZ1	7981.0
H2AC20	7915.0
H4C8	7890.0
NUP107	7884.0
NUP37	7663.0
H4C12	7649.0
RAN	7541.0
H4C3	7349.0
H4C9	7126.0
POLR2H	6733.0
RAE1	6609.0
H2BC8	6516.0
NUP98	6483.0
POLR2E	6396.0
H2AJ	6389.0
H2AZ2	5736.0
H4C5	5555.0
NUP205	5001.0
H2AX	4347.0
H3C11	4283.0
POLR2B	4109.0
H3C1	3952.0
NUP62	3934.0
H3-3A	3716.0
H3-3B	3343.0
NUP153	3242.0
POLR2I	3030.0
H3C10	2893.0
H4C13	2565.0
NUP85	2436.0
AGO2	783.0
POLR2G	642.0
H4C1	603.0
TNRC6A	595.0
RANBP2	399.0
SEH1L	380.0
H2AC4	375.0
H2BC5	293.0
POLR2F	290.0
NUP43	275.0
H4C6	33.0
H2BC12	15.0
POM121	-827.0
NUP88	-1114.0
NUP160	-1205.0
NUP54	-1247.0
NDC1	-1446.0
H4C2	-1930.0
H2BC13	-2522.0
NUP155	-2587.0
POLR2A	-2921.0
NUP210	-3859.0
NUP188	-4504.0
AAAS	-4776.0
H2BC17	-4820.0
AGO1	-5438.0
NUP133	-5454.0
TPR	-5901.0
NUP58	-5994.0
NUP93	-6202.0
NUP214	-6332.0
H4C4	-6811.0
SEC13	-6884.0
H2BC1	-7243.0
H2BC3	-7283.0
H4C11	-7768.0
H2BC6	-7780.0
POLR2C	-8417.0
H3C6	-9199.0
POLR2J	-9831.0

---

REACTOME_INFLUENZA_INFECTION

REACTOME_INFLUENZA_INFECTION

	228
set	REACTOME_INFLUENZA_INFECTION
setSize	149
pANOVA	0.000404
s.dist	0.168
p.adjustANOVA	0.0179

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL10L	11612
FAU	10809
RPS3	10729
RPL10A	10664
CANX	10592
RPS11	10587
POM121C	10520
POLR2L	10239
NUP50	10237
GRSF1	10148
RPL37A	10142
RPS15A	10069
RPS27	9839
RPL30	9827
RPL38	9821
RPS28	9794
RPLP1	9720
NUP35	9667
POLR2K	9561
RPL27	9441

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL10L	11612.0
FAU	10809.0
RPS3	10729.0
RPL10A	10664.0
CANX	10592.0
RPS11	10587.0
POM121C	10520.0
POLR2L	10239.0
NUP50	10237.0
GRSF1	10148.0
RPL37A	10142.0
RPS15A	10069.0
RPS27	9839.0
RPL30	9827.0
RPL38	9821.0
RPS28	9794.0
RPLP1	9720.0
NUP35	9667.0
POLR2K	9561.0
RPL27	9441.0
RPL22L1	9297.0
RPS5	9280.0
POLR2D	9276.0
RPLP0	9243.0
RPL15	9182.0
RPL12	9097.0
RPL13A	8817.5
RPS27L	8690.0
NUP42	8689.0
RPL13	8465.0
RPL26	8334.0
RPS9	8300.0
RPL36AL	8178.5
RPL9	8114.0
RPS27A	8106.0
RPS6	8097.0
RPL35	8050.0
RPL27A	7990.0
NUP107	7884.0
NUP37	7663.0
RPS16	7626.0
RAN	7541.0
RPS15	7463.0
RPS24	7430.0
CLTA	7409.0
RPS10	7327.0
RPL34	7322.0
RPL7	7281.0
RPL23	7239.0
RPL6	6769.0
POLR2H	6733.0
RPL17	6670.0
RPL7A	6664.0
RPL18A	6615.0
RAE1	6609.0
RPL5	6595.0
NUP98	6483.0
POLR2E	6396.0
XPO1	6362.0
RPL41	6359.0
RPL8	6213.0
RPS3A	6057.0
RPL23A	5805.0
RPS18	5767.0
RPS14	5716.0
UBA52	5407.0
CALR	5285.0
RPL26L1	5040.0
NUP205	5001.0
POLR2B	4109.0
RPL31	4100.0
NUP62	3934.0
RPL24	3372.0
NUP153	3242.0
RPL14	3033.0
POLR2I	3030.0
RPS7	2583.0
RPL29	2563.0
RPL4	2539.0
NUP85	2436.0
RPL11	1986.0
RPS29	1784.0
GTF2F1	1584.0
RPL3	1194.0
RPS26	1092.0
KPNA2	1064.0
DNAJC3	880.0
RPLP2	844.0
RPS8	808.0
RPL37	742.0
POLR2G	642.0
RANBP2	399.0
RPL28	382.0
SEH1L	380.0
RPS25	379.0
POLR2F	290.0
NUP43	275.0
RPL21	189.0
RPS21	153.0
KPNA3	117.0
PABPN1	42.0
RPL35A	-148.0
RPL19	-158.0
POM121	-827.0
RPS13	-895.0
NUP88	-1114.0
RPS12	-1124.0
RPS23	-1129.0
NUP160	-1205.0
TGFB1	-1214.0
NUP54	-1247.0
KPNA4	-1248.0
RPL18	-1323.0
NDC1	-1446.0
EIF2AK2	-2271.0
RPS20	-2282.0
CLTC	-2358.0
NUP155	-2587.0
HSP90AA1	-2720.0
PARP1	-2723.0
KPNA1	-2867.0
RPSA	-2910.0
POLR2A	-2921.0
CPSF4	-2999.0
RPL39L	-3199.0
GTF2F2	-3493.0
IPO5	-3557.0
RPL36	-3656.0
NUP210	-3859.0
RPL32	-4143.0
NUP188	-4504.0
AAAS	-4776.0
HSPA1A	-5017.0
NUP133	-5454.0
TPR	-5901.0
NUP58	-5994.0
RPS2	-6039.0
ISG15	-6080.0
NUP93	-6202.0
NUP214	-6332.0
KPNB1	-6735.0
SEC13	-6884.0
RPS19	-6970.0
KPNA5	-7133.0
KPNA7	-7180.0
RPL22	-8308.0
POLR2C	-8417.0
RPL3L	-8798.0
POLR2J	-9831.0

---

REACTOME_ERCC6_CSB_AND_EHMT2_G9A_POSITIVELY_REGULATE_RRNA_EXPRESSION

REACTOME_ERCC6_CSB_AND_EHMT2_G9A_POSITIVELY_REGULATE_RRNA_EXPRESSION

	738
set	REACTOME_ERCC6_CSB_AND_EHMT2_G9A_POSITIVELY_REGULATE_RRNA_EXPRESSION
setSize	68
pANOVA	0.000416
s.dist	0.247
p.adjustANOVA	0.018

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
H3C8	9291.0
H2BC10	9197.0
H2AC7	8965.5
H2BC7	8965.5
H3C12	8767.0
H2AC8	8539.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
H3C8	9291.0
H2BC10	9197.0
H2AC7	8965.5
H2BC7	8965.5
H3C12	8767.0
H2AC8	8539.0
H3C3	8281.0
H2BC11	8255.0
H2AZ1	7981.0
H2AC20	7915.0
H4C8	7890.0
H4C12	7649.0
H4C3	7349.0
H4C9	7126.0
HDAC1	6863.0
CBX3	6759.0
H2BC8	6516.0
H2AJ	6389.0
H2AZ2	5736.0
H4C5	5555.0
H2AX	4347.0
H3C11	4283.0
H3C1	3952.0
H3-3A	3716.0
GATAD2B	3344.0
H3-3B	3343.0
H3C10	2893.0
H4C13	2565.0
MTA1	738.0
ERCC6	694.0
CHD4	626.0
H4C1	603.0
CHD3	432.0
H2AC4	375.0
H2BC5	293.0
MBD3	142.0
H4C6	33.0
H2BC12	15.0
RBBP4	-35.0
H4C2	-1930.0
HDAC2	-2069.0
H2BC13	-2522.0
MTA2	-3127.0
EHMT2	-3734.0
TTF1	-4061.0
GATAD2A	-4623.0
H2BC17	-4820.0
H4C4	-6811.0
H2BC1	-7243.0
H2BC3	-7283.0
MTA3	-7287.0
H4C11	-7768.0
H2BC6	-7780.0
H3C6	-9199.0

---

REACTOME_ASYMMETRIC_LOCALIZATION_OF_PCP_PROTEINS

REACTOME_ASYMMETRIC_LOCALIZATION_OF_PCP_PROTEINS

	821
set	REACTOME_ASYMMETRIC_LOCALIZATION_OF_PCP_PROTEINS
setSize	63
pANOVA	0.000469
s.dist	0.255
p.adjustANOVA	0.0193

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PSMB10	10756
PSMB11	10643
PSMD2	10583
PSMB3	10477
FZD5	10472
PSMA3	10095
PRICKLE1	10061
PSMD13	9995
PSMA4	9855
PSMB1	9750
FZD8	9674
PSMF1	9417
PSME1	9374
PSMA6	8867
PSMA5	8596
PSMC5	8218
RPS27A	8106
PSMD12	7877
UBB	7699
PSMA7	7538

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PSMB10	10756.0
PSMB11	10643.0
PSMD2	10583.0
PSMB3	10477.0
FZD5	10472.0
PSMA3	10095.0
PRICKLE1	10061.0
PSMD13	9995.0
PSMA4	9855.0
PSMB1	9750.0
FZD8	9674.0
PSMF1	9417.0
PSME1	9374.0
PSMA6	8867.0
PSMA5	8596.0
PSMC5	8218.0
RPS27A	8106.0
PSMD12	7877.0
UBB	7699.0
PSMA7	7538.0
PSMD4	7467.0
SCRIB	7356.0
PARD6A	7122.5
PSME4	6787.0
FZD1	6681.0
PSMB8	6451.0
PSMB2	6330.0
PSMC3	6214.0
UBA52	5407.0
FZD4	5202.0
SEM1	5154.0
PSMC2	4855.0
PSMA1	4619.0
WNT5A	4504.0
PSMB9	4456.0
VANGL2	4372.0
PSMB5	3878.0
PSMD7	3822.0
DVL2	3530.0
FZD2	3179.0
FZD3	3164.0
FZD7	2334.0
PSMB4	2167.0
PSMD1	2120.0
PSMA2	2110.0
PSMD8	1241.0
PSME2	1076.0
PSMD3	-900.0
PSMD14	-1456.0
PSMD6	-1616.0
PSMC4	-1875.0
PSMD9	-2211.0
PSMC1	-3824.0
UBC	-3854.0
SMURF2	-4508.0
PSMB6	-4529.0
PSMD11	-4817.0
PSMB7	-6036.0
PSMD5	-6141.0
SMURF1	-6309.0
PSME3	-6565.0
PSMC6	-6973.0
PSMA8	-7408.0

---

REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION

REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION

	1163
set	REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION
setSize	102
pANOVA	0.000469
s.dist	0.2
p.adjustANOVA	0.0193

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC6	11639.0
RRN3	11200.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
POLR2L	10239.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
POLR2K	9561.0
H3C8	9291.0
H2BC10	9197.0
TBP	9059.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC6	11639.0
RRN3	11200.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
POLR2L	10239.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
POLR2K	9561.0
H3C8	9291.0
H2BC10	9197.0
TBP	9059.0
H2AC7	8965.5
H2BC7	8965.5
H3C12	8767.0
CDK7	8660.0
H2AC8	8539.0
H3C3	8281.0
H2BC11	8255.0
TAF1A	8186.0
H2AZ1	7981.0
POLR1H	7961.0
H2AC20	7915.0
H4C8	7890.0
H4C12	7649.0
H4C3	7349.0
GTF2H3	7271.0
H4C9	7126.0
TAF1D	6989.0
POLR1C	6895.0
HDAC1	6863.0
CBX3	6759.0
POLR2H	6733.0
POLR1D	6572.0
H2BC8	6516.0
POLR2E	6396.0
H2AJ	6389.0
H2AZ2	5736.0
H4C5	5555.0
GTF2H1	5260.0
TAF1B	5139.0
POLR1F	4789.0
H2AX	4347.0
H3C11	4283.0
H3C1	3952.0
H3-3A	3716.0
GATAD2B	3344.0
H3-3B	3343.0
MBD2	3169.0
UBTF	3135.0
H3C10	2893.0
H4C13	2565.0
MNAT1	1338.0
GTF2H5	1284.0
MTA1	738.0
ERCC6	694.0
CHD4	626.0
H4C1	603.0
POLR1G	474.0
CHD3	432.0
H2AC4	375.0
H2BC5	293.0
POLR2F	290.0
MBD3	142.0
H4C6	33.0
H2BC12	15.0
RBBP4	-35.0
POLR1B	-932.0
ERCC3	-1166.0
POLR1E	-1569.0
H4C2	-1930.0
HDAC2	-2069.0
H2BC13	-2522.0
MTA2	-3127.0
EHMT2	-3734.0
MAPK3	-3768.0
TTF1	-4061.0
POLR1A	-4222.0
CCNH	-4515.0
GATAD2A	-4623.0
H2BC17	-4820.0
KAT2A	-5086.0
ERCC2	-5812.0
KAT2B	-6305.0
GTF2H4	-6593.0
H4C4	-6811.0
H2BC1	-7243.0
H2BC3	-7283.0
MTA3	-7287.0
H4C11	-7768.0
H2BC6	-7780.0
CAVIN1	-7818.0
TAF1C	-8729.0
H3C6	-9199.0

---

REACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

REACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

	381
set	REACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX
setSize	85
pANOVA	0.000487
s.dist	0.219
p.adjustANOVA	0.0195

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC6	11639.0
RBBP5	11312.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
MYC	9848.0
H3C8	9291.0
H2BC10	9197.0
AXIN2	9107.0
H2AC7	8965.5

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC6	11639.0
RBBP5	11312.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
MYC	9848.0
H3C8	9291.0
H2BC10	9197.0
AXIN2	9107.0
H2AC7	8965.5
H2BC7	8965.5
H3C12	8767.0
H2AC8	8539.0
H3C3	8281.0
H2BC11	8255.0
H2AZ1	7981.0
H2AC20	7915.0
H4C8	7890.0
H4C12	7649.0
PYGO2	7568.0
H4C3	7349.0
H4C9	7126.0
TCF7	7044.0
HDAC1	6863.0
H2BC8	6516.0
H2AJ	6389.0
H2AZ2	5736.0
H4C5	5555.0
RUNX3	5211.0
LEF1	5095.0
TLE4	4839.0
TCF4	4536.0
H2AX	4347.0
H3C11	4283.0
MEN1	4097.0
H3C1	3952.0
H3-3A	3716.0
H3-3B	3343.0
BCL9	3265.0
H3C10	2893.0
CDC73	2826.0
H4C13	2565.0
KAT5	2550.0
TLE3	1882.0
RUVBL1	1837.0
LEO1	1724.0
TERT	1523.0
TCF7L2	896.0
H4C1	603.0
TCF7L1	561.0
H2AC4	375.0
H2BC5	293.0
H4C6	33.0
H2BC12	15.0
PYGO1	-625.0
CREBBP	-1522.0
CTNNB1	-1832.0
H4C2	-1930.0
ASH2L	-2171.0
H2BC13	-2522.0
EP300	-3520.0
H2BC17	-4820.0
TRRAP	-5405.0
SMARCA4	-5508.0
H3-4	-6526.0
H4C4	-6811.0
H2BC1	-7243.0
H2BC3	-7283.0
H4C11	-7768.0
H2BC6	-7780.0
TLE1	-7987.0
TLE2	-8109.0
KMT2D	-8184.0
H3C6	-9199.0
BCL9L	-9852.0

---

REACTOME_RESPIRATORY_ELECTRON_TRANSPORT

REACTOME_RESPIRATORY_ELECTRON_TRANSPORT

	1026
set	REACTOME_RESPIRATORY_ELECTRON_TRANSPORT
setSize	90
pANOVA	0.000561
s.dist	0.21
p.adjustANOVA	0.0219

Top enriched genes

Top 20 genes

GeneID	Gene Rank
UQCRB	11808
COX6B1	11101
NDUFA4	10897
NDUFA8	10698
NDUFB5	10695
TIMMDC1	10471
NDUFB3	10093
NDUFB1	9888
NDUFA3	9660
NDUFS4	9658
UQCRH	9525
NDUFA9	9323
NDUFS7	9301
TMEM126B	9106
COX6A1	9035
NDUFB4	8960
COX8A	8799
COX7A2L	8528
COX20	8391
ETFDH	8303

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
UQCRB	11808
COX6B1	11101
NDUFA4	10897
NDUFA8	10698
NDUFB5	10695
TIMMDC1	10471
NDUFB3	10093
NDUFB1	9888
NDUFA3	9660
NDUFS4	9658
UQCRH	9525
NDUFA9	9323
NDUFS7	9301
TMEM126B	9106
COX6A1	9035
NDUFB4	8960
COX8A	8799
COX7A2L	8528
COX20	8391
ETFDH	8303
NDUFAF4	8230
NDUFV2	8158
NDUFV3	8125
NDUFA6	7985
UQCRC2	7911
NDUFAF7	7910
COX5B	7869
NDUFS1	7683
UQCR10	7523
CYCS	7449
NUBPL	7338
NDUFS6	7214
COQ10B	6680
SDHC	6639
ETFB	6380
COX6C	6280
NDUFAF1	5927
UQCR11	5771
NDUFB6	5346
NDUFAF2	5206
COX4I1	5182
SCO1	5014
COX11	4320
COX18	4252
COQ10A	3899
NDUFS3	3776
SDHB	3538
UQCRC1	3391
TMEM186	3170
COX7C	3091
ECSIT	2406
NDUFS5	2404
NDUFAF5	1873
NDUFB10	1753
NDUFB7	1649
SDHD	1509
NDUFA2	1456
NDUFA12	992
NDUFC1	930
NDUFB2	842
NDUFA11	700
COX5A	695
UQCRQ	585
TACO1	523
NDUFAF3	519
NDUFA7	320
LRPPRC	-365
ETFA	-426
NDUFA10	-922
NDUFC2	-1334
ACAD9	-1350
COA1	-2402
NDUFAF6	-2543
NDUFS8	-2728
COX19	-2736
TRAP1	-3017
COX16	-3336
COX14	-4123
SURF1	-4207
SCO2	-4239
NDUFA13	-4849
NDUFA5	-5034
CYC1	-5055
NDUFS2	-5361
NDUFB8	-5594
NDUFB9	-5833
SDHA	-6233
UQCRFS1	-6502
NDUFAB1	-7763
NDUFV1	-9072

---

REACTOME_DEFECTIVE_CFTR_CAUSES_CYSTIC_FIBROSIS

REACTOME_DEFECTIVE_CFTR_CAUSES_CYSTIC_FIBROSIS

	989
set	REACTOME_DEFECTIVE_CFTR_CAUSES_CYSTIC_FIBROSIS
setSize	60
pANOVA	0.000638
s.dist	0.255
p.adjustANOVA	0.0239

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PSMB10	10756
PSMB11	10643
PSMD2	10583
PSMB3	10477
PSMA3	10095
PSMD13	9995
PSMA4	9855
PSMB1	9750
RNF5	9433
PSMF1	9417
PSME1	9374
PSMA6	8867
RNF185	8827
PSMA5	8596
DERL2	8288
PSMC5	8218
RPS27A	8106
DERL1	7889
PSMD12	7877
ERLIN1	7730

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PSMB10	10756
PSMB11	10643
PSMD2	10583
PSMB3	10477
PSMA3	10095
PSMD13	9995
PSMA4	9855
PSMB1	9750
RNF5	9433
PSMF1	9417
PSME1	9374
PSMA6	8867
RNF185	8827
PSMA5	8596
DERL2	8288
PSMC5	8218
RPS27A	8106
DERL1	7889
PSMD12	7877
ERLIN1	7730
UBB	7699
PSMA7	7538
PSMD4	7467
VCP	7321
PSME4	6787
PSMB8	6451
PSMB2	6330
PSMC3	6214
SEL1L	5556
UBA52	5407
SEM1	5154
PSMC2	4855
PSMA1	4619
PSMB9	4456
PSMB5	3878
PSMD7	3822
DERL3	2759
CFTR	2386
PSMB4	2167
PSMD1	2120
PSMA2	2110
ERLEC1	1877
PSMD8	1241
PSME2	1076
PSMD3	-900
PSMD14	-1456
PSMD6	-1616
PSMC4	-1875
PSMD9	-2211
OS9	-2223
PSMC1	-3824
UBC	-3854
ERLIN2	-4402
PSMB6	-4529
PSMD11	-4817
PSMB7	-6036
PSMD5	-6141
PSME3	-6565
PSMC6	-6973
PSMA8	-7408

---

REACTOME_BETA_DEFENSINS

REACTOME_BETA_DEFENSINS

	110
set	REACTOME_BETA_DEFENSINS
setSize	27
pANOVA	0.00064
s.dist	0.38
p.adjustANOVA	0.0239

Top enriched genes

Top 20 genes

GeneID	Gene Rank
DEFB129	11936.0
DEFB119	11669.0
DEFB110	11594.0
DEFB114	11346.0
DEFB118	10759.0
DEFB123	10534.0
DEFB128	10424.0
DEFB135	9927.0
CCR6	9400.0
CCR2	8950.0
DEFB126	8506.0
DEFB1	7108.0
DEFB104A	7023.5
DEFB104B	7023.5
DEFB121	6840.0
DEFB125	4788.0
TLR2	4730.0
DEFB136	3858.0
DEFB116	3825.0
DEFB132	3693.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
DEFB129	11936.0
DEFB119	11669.0
DEFB110	11594.0
DEFB114	11346.0
DEFB118	10759.0
DEFB123	10534.0
DEFB128	10424.0
DEFB135	9927.0
CCR6	9400.0
CCR2	8950.0
DEFB126	8506.0
DEFB1	7108.0
DEFB104A	7023.5
DEFB104B	7023.5
DEFB121	6840.0
DEFB125	4788.0
TLR2	4730.0
DEFB136	3858.0
DEFB116	3825.0
DEFB132	3693.0
DEFB133	367.0
DEFB124	-654.0
DEFB127	-2579.0
DEFB134	-3632.0
DEFB113	-5124.0
DEFB115	-5335.0
TLR1	-6710.0

---

REACTOME_DEVELOPMENTAL_BIOLOGY

REACTOME_DEVELOPMENTAL_BIOLOGY

	76
set	REACTOME_DEVELOPMENTAL_BIOLOGY
setSize	1115
pANOVA	0.000903
s.dist	0.0589
p.adjustANOVA	0.033

Top enriched genes

Top 20 genes

GeneID	Gene Rank
LCE6A	11877
KRTAP21-1	11874
LCE3D	11851
KRTAP19-3	11798
SPRR3	11777
IAPP	11775
KRT6A	11769
LCE2B	11763
KRTAP10-6	11700
H2AC6	11639
KRTAP5-4	11623
RPL10L	11612
KRTAP19-5	11557
KRT31	11542
KRTAP21-3	11536
SCN3A	11501
CELA2A	11468
CNTN6	11450
KRTAP9-1	11403
LCE3E	11380

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
LCE6A	11877.0
KRTAP21-1	11874.0
LCE3D	11851.0
KRTAP19-3	11798.0
SPRR3	11777.0
IAPP	11775.0
KRT6A	11769.0
LCE2B	11763.0
KRTAP10-6	11700.0
H2AC6	11639.0
KRTAP5-4	11623.0
RPL10L	11612.0
KRTAP19-5	11557.0
KRT31	11542.0
KRTAP21-3	11536.0
SCN3A	11501.0
CELA2A	11468.0
CNTN6	11450.0
KRTAP9-1	11403.0
LCE3E	11380.0
RBBP5	11312.0
PSPN	11301.0
KRT24	11286.0
KRTAP11-1	11266.0
KRTAP15-1	11263.0
DSC1	11250.0
H2AC18	11198.5
H2AC19	11198.5
LCE1C	11188.0
TREM2	11160.0
SPINK6	11096.0
H2BC14	11048.0
KRT33B	11047.0
LCE2C	11023.0
LCE4A	11014.0
KRT14	11004.0
KRTAP19-1	10934.0
KRTAP4-5	10871.0
NODAL	10853.0
FAU	10809.0
PSMB10	10756.0
SPRR1B	10737.0
RPS3	10729.0
KRTAP4-11	10706.0
PCK1	10694.0
RPL10A	10664.0
PSMB11	10643.0
H2AC14	10639.0
KRT76	10637.0
GFRA1	10620.0
RPS11	10587.0
PSMD2	10583.0
KRTAP22-1	10524.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
NANOG	10491.0
PSMB3	10477.0
NCOA6	10453.0
MAPK14	10451.0
H3C4	10448.0
KRT32	10422.0
LHX9	10402.0
KRT25	10392.0
PFN1	10391.0
KRT82	10357.0
PSENEN	10355.0
H2BC26	10335.0
MED20	10313.0
KRTAP16-1	10305.0
KIF4B	10295.0
KRTAP10-10	10292.0
POLR2L	10239.0
ARPC3	10224.0
H4C16	10207.0
ROBO1	10159.0
RPL37A	10142.0
KRT13	10133.0
CD36	10104.0
PSMA3	10095.0
RPS15A	10069.0
H2BC21	10024.0
H3C2	10000.0
PSMD13	9995.0
KRTAP24-1	9984.0
PERP	9946.0
GAP43	9929.0
H2BC15	9893.0
HOXD1	9870.0
PSMA4	9855.0
MYC	9848.0
RPS27	9839.0
RPL30	9827.0
RPL38	9821.0
ISL1	9816.0
SOX2	9810.0
TUBA3D	9809.0
RPS28	9794.0
MYOD1	9790.0
HNF4A	9787.0
KRT78	9780.0
DOK2	9760.0
LIPJ	9755.0
PSMB1	9750.0
CTNNA2	9743.0
RPLP1	9720.0
LGI3	9672.0
HOXD4	9671.0
PIK3CA	9654.0
SH3GL2	9631.0
TRPC7	9596.0
TUBA1B	9567.0
POLR2K	9561.0
MSGN1	9556.0
MED11	9555.0
UNC5D	9535.0
ARPC5	9533.0
ENAH	9521.0
FRS2	9518.0
WT1	9506.0
KRTAP19-4	9505.0
MMP2	9503.0
KALRN	9490.0
ELOB	9471.0
MED17	9468.0
IVL	9443.0
RPL27	9441.0
KLK14	9429.0
PSMF1	9417.0
PSME1	9374.0
GATA4	9352.0
RPL22L1	9297.0
H3C8	9291.0
KRTAP6-3	9288.0
RPS5	9280.0
POLR2D	9276.0
RPLP0	9243.0
H2BC10	9197.0
RPL15	9182.0
CDH2	9176.0
RASA1	9154.0
PKP2	9128.0
SHC3	9101.0
RPL12	9097.0
KRTAP2-2	9081.0
MYL12A	9074.0
LCE2D	9070.0
RELA	9063.0
NELL2	9005.0
CNTN2	8992.0
DHH	8988.0
MED4	8985.0
H2AC7	8965.5
H2BC7	8965.5
KRT39	8940.0
SPINK5	8910.0
TGM5	8899.0
PSMA6	8867.0
KRTAP12-3	8842.0
HOXA3	8839.0
RPL13A	8817.5
SCN9A	8802.0
H3C12	8767.0
MED1	8758.0
UNC5B	8727.0
GRIN2B	8696.0
KRTAP13-4	8694.0
RPS27L	8690.0
PTF1A	8662.0
CACNB2	8636.0
KRTAP10-2	8599.0
PSMA5	8596.0
H2AC8	8539.0
DSG1	8519.0
RPL13	8465.0
LHX2	8400.0
KLK12	8384.0
CXCL12	8350.0
RPL26	8334.0
NRAS	8328.0
WWTR1	8325.0
NKX2-2	8319.0
PTPN11	8317.0
RPS9	8300.0
H3C3	8281.0
CSTA	8272.0
H2BC11	8255.0
CSF3R	8242.0
EGFR	8241.0
PSMC5	8218.0
DOK1	8194.0
RPL36AL	8178.5
BOC	8171.0
UNC5C	8121.0
RPL9	8114.0
RPS27A	8106.0
RPS6	8097.0
CDON	8096.0
SEMA3E	8091.0
CASP14	8075.0
RBX1	8051.0
RPL35	8050.0
TRPC6	8048.0
TRIO	8024.0
RPL27A	7990.0
H2AZ1	7981.0
PTPRC	7945.0
FGF10	7931.0
LCE1E	7920.0
H2AC20	7915.0
H4C8	7890.0
RBPJ	7881.0
PSMD12	7877.0
MED9	7861.0
MAP2K6	7860.0
MYF6	7829.0
MED22	7819.0
MPZ	7804.0
HJV	7793.0
SDC2	7776.0
KRTAP26-1	7768.0
LAMC1	7733.0
RRAS	7711.0
EPHA5	7706.0
UBB	7699.0
KRTAP19-2	7694.0
DCC	7693.0
ARHGEF11	7659.0
COL4A2	7651.0
MYO10	7650.0
H4C12	7649.0
ACTR3	7643.0
RPS16	7626.0
ARPC4	7625.0
DRAP1	7617.0
SNW1	7608.0
KRT36	7571.0
MSI1	7570.0
LCE2A	7556.0
PSMA7	7538.0
TUBB8	7487.0
SLIT2	7480.0
PSMD4	7467.0
RPS15	7463.0
KRTAP2-3	7451.0
RPS24	7430.0
SPRR2D	7427.0
CLTA	7409.0
TLN1	7398.0
PPARGC1A	7385.0
H4C3	7349.0
NFASC	7333.0
SCN5A	7330.0
RPS10	7327.0
RPL34	7322.0
EFNB2	7319.0
RPL7	7281.0
EPHA6	7246.0
RPL23	7239.0
ONECUT3	7231.0
POU3F2	7229.0
ARPC2	7206.0
ALCAM	7196.0
ST8SIA4	7186.0
KLF4	7174.0
TBXT	7150.0
ACTB	7138.0
H4C9	7126.0
NEUROD1	7111.0
KRTAP10-1	7107.0
DOK6	7076.0
SCN2A	7046.0
TCF7	7044.0
NKX6-1	7018.0
COL4A1	7011.0
MESP2	6981.0
KCNQ3	6964.0
SHH	6950.0
PAGR1	6944.0
KRTAP6-2	6907.0
LGI2	6904.0
LAMA2	6900.0
WNT3A	6899.0
LPL	6882.0
DNM1	6880.0
ST8SIA2	6877.0
DPYSL3	6874.0
ITGA2	6860.0
DPYSL5	6843.0
GSC	6819.0
ADAM23	6808.0
PSME4	6787.0
RPL6	6769.0
PLXNB1	6763.0
AGRN	6754.0
RARB	6736.0
POLR2H	6733.0
CDK5R1	6726.0
CACNG4	6715.0
DSC3	6696.0
RPL17	6670.0
RPL7A	6664.0
CACNA1H	6621.0
RPL18A	6615.0
DOCK1	6611.0
MED28	6601.0
RPL5	6595.0
KRTAP10-8	6587.0
DSP	6563.0
NCAM1	6524.0
H2BC8	6516.0
RPTN	6482.0
PSMB8	6451.0
EZH2	6449.0
POLR2E	6396.0
H2AJ	6389.0
RPL41	6359.0
KRTAP5-2	6347.0
PSMB2	6330.0
MAP2K1	6326.0
PAX4	6303.0
KRTAP9-3	6298.0
CHL1	6286.0
COL5A1	6252.0
ZNF335	6242.0
EOMES	6215.0
PSMC3	6214.0
RPL8	6213.0
LCE1A	6207.0
SALL1	6201.0
KAZN	6198.0
COL5A2	6190.0
STX1B	6162.0
FOXL2	6159.0
RELN	6129.0
SPTB	6072.0
COL9A1	6065.0
PBX1	6059.0
RPS3A	6057.0
ROBO2	6043.0
SUZ12	6038.0
GATA2	6033.0
ANK2	5978.0
KRTAP3-2	5892.0
TEAD4	5884.0
SCN10A	5880.0
CACNG3	5867.0
PIK3R1	5836.0
RPL23A	5805.0
KRT10	5781.0
RPS18	5767.0
MAFB	5746.0
H2AZ2	5736.0
KRT27	5732.0
RPS14	5716.0
MED8	5712.0
AP2S1	5697.0
ARHGAP39	5675.0
MED29	5671.0
ABLIM3	5620.0
KRTAP4-1	5591.0
FOXA3	5584.0
KRT4	5579.0
H4C5	5555.0
BMP4	5542.0
TUBB4B	5539.0
KRAS	5535.0
HOXA2	5499.0
PAK5	5468.0
RGMB	5465.0
UNC5A	5442.0
SHTN1	5439.0
UBA52	5407.0
CDC42	5404.0
SCN7A	5264.0
KRT1	5254.0
PPARG	5229.0
PMP22	5216.0
COL6A5	5213.0
LDB1	5174.0
SEM1	5154.0
GRB10	5109.0
KRTAP27-1	5097.0
LEF1	5095.0
DKK1	5074.0
SCN11A	5048.0
RPL26L1	5040.0
EFNB3	5027.0
STAT3	5024.0
PFN2	5021.0
MED21	5010.0
MYH14	5005.0
NEUROG3	4975.0
POU5F1	4944.0
LAMB1	4940.0
DAB1	4920.0
PSMC2	4855.0
GDNF	4799.0
TIAM1	4790.0
KRT20	4774.0
ADGRG6	4686.0
KRTAP5-5	4671.0
SPTBN2	4669.0
KRTAP17-1	4667.0
ANK1	4647.0
PTK2	4627.0
PSMA1	4619.0
IL6R	4607.0
SRGAP2	4579.0
SCN3B	4561.0
TCF4	4536.0
THRAP3	4526.0
MEF2B	4503.0
FOXA1	4480.0
KMT2A	4467.0
IRS2	4466.0
PSMB9	4456.0
NCAN	4427.0
PIK3CD	4402.0
SEMA5A	4398.0
H2AX	4347.0
ETF1	4345.0
SEMA6D	4295.0
NAB2	4293.0
H3C11	4283.0
WASL	4251.0
DLL1	4244.0
SMAD2	4243.0
TAL1	4197.0
CNOT6	4162.0
SPRR2A	4156.0
KRT71	4152.0
WNT1	4120.0
MED16	4114.0
POLR2B	4109.0
KRT23	4106.0
RPL31	4100.0
EFNA5	4033.0
ABL1	4013.0
SEMA6A	4007.0
NR6A1	3966.0
H3C1	3952.0
ITGA1	3942.0
MAPK11	3914.0
CAPN1	3898.0
RDX	3881.0
KLK8	3879.0
PSMB5	3878.0
SRGAP1	3876.0
CTCF	3864.0
KRTAP9-9	3844.0
PSMD7	3822.0
TRPC4	3809.0
EPHB3	3808.0
MYL6	3798.0
MAML1	3747.0
ACVR2B	3720.0
H3-3A	3716.0
HNF1A	3704.0
NCK1	3701.0
CASC3	3686.0
FGFR1	3685.0
RPS6KA2	3676.0
CEBPD	3627.0
HOXD3	3624.0
SLIT3	3612.0
MYH9	3586.0
ARHGEF12	3585.0
LHX4	3557.0
CDH1	3527.0
SEMA3A	3524.0
CACNA1C	3518.0
CDH15	3513.0
COL5A3	3441.0
PCGF2	3438.0
CNTN1	3431.0
VLDLR	3420.0
HOXC4	3400.0
KRT2	3399.0
COL4A3	3385.0
ROCK1	3381.0
RPL24	3372.0
ZFPM2	3345.0
H3-3B	3343.0
ST14	3338.0
MED13	3320.0
PLXNA2	3300.0
EPHA3	3261.0
NR5A2	3260.0
KRT80	3251.0
RGMA	3248.0
NEO1	3218.0
EVL	3194.0
MEF2A	3161.0
CAP1	3152.0
SOS2	3136.0
NGEF	3080.0
RBM8A	3055.0
FOXD3	3054.0
GSPT1	3039.0
RPL14	3033.0
COL3A1	3031.0
POLR2I	3030.0
FOXA2	2982.0
ADGRV1	2977.0
FYN	2974.0
MED6	2948.0
TUBB2B	2945.0
CSNK2B	2924.0
MYL12B	2919.0
SRGAP3	2914.0
MED15	2904.0
NR5A1	2894.0
H3C10	2893.0
SPRR2G	2872.0
LAMA1	2863.0
NOTO	2846.0
MEIS1	2836.0
NCBP2	2801.0
SCN8A	2785.0
PAX6	2760.0
ROCK2	2752.0
AP2B1	2731.0
KRTAP4-6	2715.0
CACNG2	2697.0
COL2A1	2681.0
KRT3	2668.0
KRT77	2659.0
TUBA1C	2647.0
HOXA1	2632.0
PLIN1	2630.0
PLXNA4	2629.0
RPS7	2583.0
KRTAP1-1	2568.0
H4C13	2565.0
RPL29	2563.0
RPL4	2539.0
CNOT9	2535.0
NCK2	2522.0
PLCG1	2505.0
KRTAP13-1	2500.0
LIPK	2459.0
FGF9	2437.0
DLG1	2422.0
DPYSL4	2395.0
KRTAP1-3	2367.0
SCN4B	2353.0
TUBB2A	2344.0
PAK6	2339.0
PML	2336.0
SLC2A4	2319.0
KRT5	2301.0
NRCAM	2259.0
LCE1F	2245.0
MED26	2192.0
PPP3CB	2190.0
GATA6	2183.0
CFL1	2178.0
PSMB4	2167.0
MEF2C	2135.0
PSMD1	2120.0
PSMA2	2110.0
NTN4	2106.0
CLTCL1	2101.0
DPPA4	2080.0
KRT38	2079.0
EBF1	2066.0
HOXB1	2040.0
TGS1	2034.0
RPL11	1986.0
KRT6B	1967.0
HES1	1909.0
TEAD1	1896.0
GAB1	1866.0
KRTAP5-8	1839.0
UTRN	1829.0
JUN	1798.0
RPS29	1784.0
MEF2D	1770.0
FOXO3	1738.0
NAB1	1709.0
MAGOH	1707.0
SCN1A	1694.0
CRMP1	1686.0
EPHB4	1682.0
TUBB3	1625.0
PSEN2	1591.0
KLK5	1561.0
KRTAP4-2	1531.0
PIK3CB	1504.0
ADAM22	1501.0
ARHGEF28	1486.0
CACNB4	1475.0
TBL1XR1	1474.0
KLK13	1469.0
MET	1436.0
SMAD4	1428.0
FGF2	1411.0
GRB2	1374.0
KRTAP20-2	1350.0
ZSCAN10	1334.0
MAGOHB	1316.0
MED18	1288.0
HNF4G	1285.0
SOS1	1280.0
ACVR1B	1277.0
PSMD8	1241.0
DSC2	1221.0
SIAH2	1213.0
RPL3	1194.0
LIPN	1171.0
MED10	1112.0
VASP	1106.0
RPS26	1092.0
PSME2	1076.0
PITPNA	1009.0
KRT40	948.0
PABPC1	854.0
RPLP2	844.0
NCBP1	823.0
RPS8	808.0
NRP2	807.0
AJUBA	804.0
CREB1	796.0
CLDN7	791.0
KRTAP29-1	747.0
CDK2	744.0
RPL37	742.0
GSK3B	734.0
LCE1B	718.0
DSCAM	703.0
COL6A6	672.0
CXCR4	668.0
POLR2G	642.0
H4C1	603.0
APH1A	587.0
RND1	580.0
GFI1	554.0
FAM120B	515.0
TUBA1A	511.0
PCSK6	487.0
SPTBN4	456.0
ONECUT1	449.0
GAB2	445.0
ITSN1	443.0
DLL3	404.0
ZNF467	390.0
RPL28	382.0
RPS25	379.0
LCE3A	377.0
H2AC4	375.0
NTN1	339.0
CCNC	300.0
SCN2B	298.0
H2BC5	293.0
POLR2F	290.0
KLF5	212.0
CLASP1	197.0
RPL21	189.0
MED19	179.0
CSNK2A2	162.0
RPS21	153.0
FARP2	112.0
FLRT3	51.0
KRTAP1-5	46.0
PDX1	40.0
H4C6	33.0
H2BC12	15.0
NCOA2	13.0
EIF4G1	-8.0
RBBP4	-35.0
CDK5	-81.0
CBFB	-89.0
EPHB6	-95.0
ACTR2	-105.0
PRNP	-125.0
RPL35A	-148.0
RPL19	-158.0
KCNQ2	-215.0
YY1	-223.0
UPF3A	-244.0
KRT26	-259.0
CACNA1S	-272.0
TUBA8	-315.0
ITGA9	-348.0
SMAD3	-356.0
PRKACA	-398.0
PRKACB	-414.0
KRTAP8-1	-420.0
MAPK12	-424.0
INSM1	-438.0
PKP4	-442.0
BNIP2	-459.0
JUP	-522.0
EPHB1	-529.0
AP2M1	-545.0
KRT83	-615.0
TNF	-621.0
DPYSL2	-628.0
EFNA3	-632.0
CDK8	-643.0
PAK1	-679.0
SIAH1	-688.0
AKT3	-693.0
NCOR1	-716.0
COL6A3	-741.0
VAV2	-863.0
MAG	-873.0
RPS13	-895.0
PSMD3	-900.0
HELZ2	-952.0
CDK4	-965.0
DNM3	-972.0
SDCBP	-994.0
DSG2	-998.0
MED25	-1008.0
EFNA4	-1033.0
MAPK7	-1038.0
CCND3	-1119.0
RPS12	-1124.0
RPS23	-1129.0
EPHA1	-1149.0
FOXP1	-1156.0
MAML3	-1158.0
HOXB2	-1178.0
ELOC	-1192.0
ANK3	-1196.0
TGFB1	-1214.0
YAP1	-1223.0
FURIN	-1279.0
LIN28A	-1304.0
RUNX1	-1307.0
RET	-1310.0
RPL18	-1323.0
EVPL	-1349.0
AP2A1	-1354.0
CDX2	-1355.0
KRTAP5-3	-1373.0
DSG4	-1376.0
ITGAV	-1379.0
ADIPOQ	-1382.0
EPHA7	-1396.0
ITGA5	-1441.0
PSMD14	-1456.0
RPS6KA5	-1482.0
MYH10	-1513.0
CREBBP	-1522.0
CUL2	-1526.0
PI3	-1549.0
TSC22D1	-1551.0
GCK	-1570.0
CER1	-1586.0
DNM2	-1605.0
PSMD6	-1616.0
EPAS1	-1620.0
CACNA1G	-1628.0
PIK3R3	-1640.0
TUBA3E	-1682.0
EPHA4	-1772.0
NRP1	-1815.0
CTNNB1	-1832.0
CSNK2A1	-1847.0
FOXF1	-1870.0
PSMC4	-1875.0
SMARCD3	-1908.0
SPTBN1	-1925.0
H4C2	-1930.0
CACNA1D	-1946.0
EGR2	-1951.0
MED23	-1972.0
PPL	-1974.0
PKNOX1	-1976.0
GRIN1	-2018.0
HRAS	-2024.0
ANGPTL4	-2062.0
VAV3	-2066.0
HDAC2	-2069.0
ABL2	-2083.0
NR2F2	-2095.0
HSP90AB1	-2111.0
ASH2L	-2171.0
SHC1	-2176.0
KRTAP25-1	-2191.0
PSMD9	-2211.0
ITGB3	-2220.0
RPS20	-2282.0
PPARA	-2290.0
EPHA8	-2319.0
NFKB1	-2329.0
SCD5	-2334.0
CLTC	-2358.0
WDR5	-2418.0
HNF1B	-2483.0
ABLIM2	-2484.0
CDH4	-2498.0
H2BC13	-2522.0
PAXIP1	-2531.0
LYN	-2552.0
KRT75	-2553.0
PRDM14	-2617.0
PSEN1	-2622.0
ROBO3	-2640.0
KRTAP12-4	-2650.0
E2F1	-2651.0
KRT33A	-2699.0
PIAS2	-2719.0
HSP90AA1	-2720.0
CEBPB	-2779.0
AKT1	-2798.0
OCLN	-2830.0
ACTG1	-2878.0
RPSA	-2910.0
POLR2A	-2921.0
ZNF638	-2924.0
CHD9	-2930.0
CACNG8	-2947.0
RHOC	-2981.0
RANBP9	-3016.0
PRKAR2A	-3061.0
SPI1	-3088.0
RARG	-3093.0
EPHB2	-3096.0
SPRR2E	-3116.0
AKAP5	-3136.0
RPS6KA4	-3154.0
KRT19	-3166.0
PLXNA1	-3191.0
RPL39L	-3199.0
TUBA4B	-3204.0
GFRA2	-3236.0
PRKACG	-3257.0
YES1	-3259.0
TGM1	-3303.0
PRKCQ	-3312.0
EZR	-3342.0
TUBA3C	-3370.0
MAML2	-3395.0
MYH11	-3414.0
MAPK8	-3449.0
PKP1	-3507.0
EP300	-3520.0
RNPS1	-3555.0
NUMB	-3575.0
TBPL2	-3591.0
APH1B	-3621.0
TCHH	-3639.0
HSPA8	-3646.0
COL4A4	-3649.0
NOTCH1	-3655.0
RPL36	-3656.0
SCN4A	-3682.0
MAPK1	-3684.0
GPC1	-3689.0
TRPC1	-3693.0
SPAG9	-3724.0
KRTAP10-9	-3751.0
MAPK3	-3768.0
PIK3R2	-3789.0
CLASP2	-3820.0
PSMC1	-3824.0
UBC	-3854.0
KRTAP2-4	-3866.0
SREBF2	-3932.0
KRTAP5-7	-3938.0
RHOA	-3956.0
GFRA3	-3961.0
SALL4	-4046.0
KRTAP23-1	-4072.0
MED13L	-4098.0
KRTAP13-3	-4108.0
MAPK13	-4116.0
UPF2	-4120.0
RPL32	-4143.0
EPHA10	-4154.0
ARHGAP35	-4158.0
KRTAP19-6	-4170.0
DEK	-4179.0
RAC1	-4187.0
TUBA4A	-4230.0
KRTAP20-1	-4257.0
MYO9B	-4292.0
DSCAML1	-4364.0
AMH	-4374.0
MYB	-4398.0
COL6A2	-4417.0
CD72	-4424.0
RFX6	-4451.0
CYP51A1	-4471.0
STX1A	-4495.0
CDK19	-4512.0
COL6A1	-4523.0
PSMB6	-4529.0
KRT35	-4533.0
TRIM33	-4586.0
NOG	-4600.0
EED	-4609.0
LHX3	-4660.0
ZSWIM8	-4662.0
KRTAP9-6	-4671.0
ARTN	-4686.0
SPTA1	-4698.0
ITGB1	-4709.0
HMGCR	-4749.0
ADAM10	-4798.0
ARPC1A	-4800.0
PSMD11	-4817.0
H2BC17	-4820.0
SEMA4A	-4846.0
SCN1B	-4869.0
MBP	-4879.0
EIF4A3	-4880.0
SPRR1A	-4890.0
ACVR2A	-4942.0
MED27	-4976.0
NCOA1	-5003.0
KMT2C	-5024.0
MED30	-5033.0
NCOA3	-5052.0
IHH	-5064.0
TFDP2	-5068.0
TCF3	-5077.0
KAT2A	-5086.0
PRKCA	-5111.0
HDAC3	-5138.0
TFDP1	-5182.0
ABLIM1	-5221.0
KRTAP5-10	-5235.0
KRT34	-5285.0
AP2A2	-5292.0
CEBPA	-5302.0
CAP2	-5345.0
SOX9	-5347.0
SPRR2F	-5401.0
KRT28	-5423.0
HOXB4	-5461.0
SMARCA4	-5508.0
KRT74	-5536.0
AKT2	-5544.0
DOK5	-5575.0
CNTNAP1	-5614.0
SOX10	-5615.0
PIP5K1C	-5627.0
PKP3	-5666.0
ADAM11	-5692.0
DAG1	-5764.0
CACNA1I	-5831.0
EFNA1	-5871.0
CTNNA1	-5880.0
NCSTN	-5917.0
ITGA10	-5945.0
KRTAP12-2	-5968.0
GDF1	-6020.0
NCOR2	-6028.0
PSMB7	-6036.0
RPS2	-6039.0
RAP1GAP	-6076.0
FLI1	-6130.0
LCE3B	-6137.0
PSMD5	-6141.0
MED31	-6155.0
PLXNC1	-6156.0
DSG3	-6277.0
KRT6C	-6280.0
KAT2B	-6305.0
CAPNS1	-6338.0
MED7	-6342.0
RXRA	-6343.0
TCF12	-6379.0
DLG4	-6384.0
USP33	-6387.0
FLG	-6432.0
LIPM	-6449.0
PSME3	-6565.0
SPINK9	-6584.0
HIF3A	-6605.0
MYL9	-6609.0
COL9A2	-6678.0
LIMK2	-6680.0
SREBF1	-6687.0
KRT18	-6693.0
KRT16	-6697.0
HHEX	-6717.0
LIMK1	-6795.0
CACNB3	-6798.0
H4C4	-6811.0
FOXH1	-6833.0
ERBB2	-6841.0
MYF5	-6906.0
RPS19	-6970.0
PSMC6	-6973.0
TUBB6	-7020.0
LCE5A	-7025.0
PTPRA	-7032.0
TEAD2	-7075.0
KRTAP4-8	-7078.0
KRT79	-7124.0
SEMA7A	-7134.0
KRTAP19-8	-7140.0
CDSN	-7141.0
ARHGEF7	-7153.0
KRTAP5-11	-7176.0
KRT9	-7223.0
KRTAP6-1	-7228.0
TUBAL3	-7240.0
H2BC1	-7243.0
H2BC3	-7283.0
PSMA8	-7408.0
EFNA2	-7415.0
PDLIM7	-7428.0
LGI4	-7436.0
ACVR1C	-7473.0
PKLR	-7478.0
SLC2A2	-7515.0
KRTAP3-1	-7524.0
MMP9	-7546.0
KRT17	-7563.0
LYPLA2	-7572.0
ITGA2B	-7597.0
SPTAN1	-7600.0
MED24	-7612.0
WNT10B	-7624.0
DMRT1	-7664.0
KRT12	-7712.0
FES	-7718.0
H4C11	-7768.0
H2BC6	-7780.0
LELP1	-7793.0
KRTAP10-4	-7811.0
POU3F1	-7833.0
FABP4	-7836.0
TRPC3	-7899.0
RHOB	-7916.0
CACNB1	-7948.0
CDKN1A	-7949.0
PRX	-7958.0
DAND5	-7959.0
LGI1	-7960.0
FOXO1	-8010.0
CARM1	-8030.0
KRTAP9-4	-8078.0
KRTAP4-3	-8126.0
KMT2D	-8184.0
COL9A3	-8188.0
SLIT1	-8237.0
RARA	-8279.0
TUBB1	-8284.0
RPL22	-8308.0
PAK2	-8311.0
KRTAP13-2	-8335.0
POLR2C	-8417.0
KRT15	-8422.0
SRC	-8426.0
KRT37	-8429.0
KRTAP4-4	-8439.0
MAFA	-8440.0
KRT72	-8441.0
SEMA4D	-8491.0
CLTB	-8520.0
PLXND1	-8552.0
SNAI1	-8560.0
KRTAP10-5	-8589.0
RPS6KA1	-8638.0
KRT7	-8643.0
MAP2K2	-8653.0
EPHA2	-8658.0
ARPC1B	-8684.0
LEP	-8704.0
KRT73	-8734.0
KRTAP19-7	-8737.0
PAK4	-8754.0
RPL3L	-8798.0
PRSS8	-8802.0
MIXL1	-8815.0
KRTAP12-1	-8858.0
INS	-8871.0
MYOG	-8918.0
NTN3	-8930.0
KRT85	-8939.0
TBX6	-8945.0
KRTAP10-11	-8987.0
KRT84	-8995.0
GIT1	-9012.0
WNT4	-9038.0
KRTAP21-2	-9058.0
LEFTY2	-9092.0
LEFTY1	-9096.0
CEBPE	-9102.0
DOK4	-9117.0
NRTN	-9146.0
H3C6	-9199.0
KRT8	-9230.0
TUBB4A	-9276.0
KRT86	-9285.0
KRT81	-9301.0
KRTAP4-7	-9307.0
SPTBN5	-9329.0
KRTAP10-3	-9338.0
AGAP2	-9432.0
KRTAP3-3	-9433.0
HOXB3	-9459.0
KRTAP10-7	-9464.0
PTGDS	-9486.0
KRTAP5-9	-9598.0
HOXA4	-9629.0
ADIRF	-9643.0
KRTAP5-1	-9676.0
GFRA4	-9696.0
TYROBP	-9715.0
KRTAP1-4	-9726.0
KRTAP2-1	-9733.0
GRB7	-9793.0
KRTAP10-12	-9821.0
POLR2J	-9831.0
KRTAP9-2	-9917.0
KRTAP5-6	-9920.0

---

REACTOME_DEFENSINS

REACTOME_DEFENSINS

	111
set	REACTOME_DEFENSINS
setSize	33
pANOVA	0.00094
s.dist	0.333
p.adjustANOVA	0.0336

Top enriched genes

Top 20 genes

GeneID	Gene Rank
DEFB129	11936.0
DEFB119	11669.0
DEFB110	11594.0
DEFB114	11346.0
DEFA4	11171.0
DEFB118	10759.0
DEFB123	10534.0
DEFB128	10424.0
DEFB135	9927.0
CCR6	9400.0
CCR2	8950.0
DEFB126	8506.0
CD4	7241.0
DEFB1	7108.0
DEFB104A	7023.5
DEFB104B	7023.5
DEFB121	6840.0
ART1	6020.0
DEFB125	4788.0
TLR2	4730.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
DEFB129	11936.0
DEFB119	11669.0
DEFB110	11594.0
DEFB114	11346.0
DEFA4	11171.0
DEFB118	10759.0
DEFB123	10534.0
DEFB128	10424.0
DEFB135	9927.0
CCR6	9400.0
CCR2	8950.0
DEFB126	8506.0
CD4	7241.0
DEFB1	7108.0
DEFB104A	7023.5
DEFB104B	7023.5
DEFB121	6840.0
ART1	6020.0
DEFB125	4788.0
TLR2	4730.0
DEFB136	3858.0
DEFB116	3825.0
DEFB132	3693.0
DEFB133	367.0
DEFB124	-654.0
PRSS3	-1954.0
DEFA5	-1982.0
DEFB127	-2579.0
DEFB134	-3632.0
DEFB113	-5124.0
DEFB115	-5335.0
DEFA6	-6354.0
TLR1	-6710.0

---

REACTOME_RHO_GTPASES_ACTIVATE_PKNS

REACTOME_RHO_GTPASES_ACTIVATE_PKNS

	915
set	REACTOME_RHO_GTPASES_ACTIVATE_PKNS
setSize	86
pANOVA	0.000961
s.dist	0.206
p.adjustANOVA	0.0336

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
SFN	10530.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
YWHAZ	9682.0
H3C8	9291.0
H2BC10	9197.0
H2AC7	8965.5
H2BC7	8965.5

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
SFN	10530.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
H2BC15	9893.0
YWHAZ	9682.0
H3C8	9291.0
H2BC10	9197.0
H2AC7	8965.5
H2BC7	8965.5
H3C12	8767.0
H2AC8	8539.0
H3C3	8281.0
H2BC11	8255.0
H2AZ1	7981.0
H2AC20	7915.0
H4C8	7890.0
H4C12	7649.0
H4C3	7349.0
H4C9	7126.0
KLK3	6520.0
H2BC8	6516.0
H2AJ	6389.0
PKN2	6344.0
YWHAB	6001.0
CDC25C	5843.0
H2AZ2	5736.0
H4C5	5555.0
MYH14	5005.0
PPP1CB	4396.0
YWHAH	4351.0
H2AX	4347.0
PDPK1	4310.0
H3C11	4283.0
H3C1	3952.0
MYL6	3798.0
H3-3A	3716.0
MYH9	3586.0
H3-3B	3343.0
MYL12B	2919.0
H3C10	2893.0
H4C13	2565.0
PPP1R12B	2180.0
PKN3	2122.0
KDM1A	1167.0
KDM4C	1048.0
H4C1	603.0
H2AC4	375.0
H2BC5	293.0
H4C6	33.0
H2BC12	15.0
NCOA2	13.0
PAK1	-679.0
PKN1	-1271.0
MYH10	-1513.0
YWHAQ	-1911.0
H4C2	-1930.0
YWHAE	-2361.0
H2BC13	-2522.0
RHOC	-2981.0
MYH11	-3414.0
KLK2	-3691.0
PPP1R12A	-3794.0
RHOA	-3956.0
RAC1	-4187.0
H2BC17	-4820.0
YWHAG	-6321.0
MYL9	-6609.0
PPP1R14A	-6612.0
H4C4	-6811.0
H2BC1	-7243.0
H2BC3	-7283.0
H4C11	-7768.0
H2BC6	-7780.0
RHOB	-7916.0
H3C6	-9199.0

---

REACTOME_DNA_REPLICATION_PRE_INITIATION

REACTOME_DNA_REPLICATION_PRE_INITIATION

	1101
set	REACTOME_DNA_REPLICATION_PRE_INITIATION
setSize	150
pANOVA	0.00104
s.dist	0.155
p.adjustANOVA	0.0352

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
PSMB10	10756.0
H2AC14	10639.0
PSMD2	10583.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
PSMB3	10477.0
H3C4	10448.0
H2BC26	10335.0
H4C16	10207.0
PSMA3	10095.0
H2BC21	10024.0
H3C2	10000.0
PSMD13	9995.0
H2BC15	9893.0
PSMA4	9855.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
PSMB10	10756.0
H2AC14	10639.0
PSMD2	10583.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
PSMB3	10477.0
H3C4	10448.0
H2BC26	10335.0
H4C16	10207.0
PSMA3	10095.0
H2BC21	10024.0
H3C2	10000.0
PSMD13	9995.0
H2BC15	9893.0
PSMA4	9855.0
PSMB1	9750.0
RPA2	9717.0
PSMF1	9417.0
PSME1	9374.0
H3C8	9291.0
H2BC10	9197.0
H2AC7	8965.5
H2BC7	8965.5
PSMA6	8867.0
H3C12	8767.0
MCM2	8703.0
PSMA5	8596.0
H2AC8	8539.0
MCM8	8324.0
H3C3	8281.0
H2BC11	8255.0
PSMC5	8218.0
RPS27A	8106.0
ORC1	8043.0
H2AZ1	7981.0
H2AC20	7915.0
H4C8	7890.0
PSMD12	7877.0
UBB	7699.0
H4C12	7649.0
PSMA7	7538.0
PSMD4	7467.0
H4C3	7349.0
H4C9	7126.0
MCM3	6870.0
ORC6	6542.0
H2BC8	6516.0
PSMB8	6451.0
H2AJ	6389.0
PSMB2	6330.0
PSMC3	6214.0
CDT1	6204.0
H2AZ2	5736.0
H4C5	5555.0
UBA52	5407.0
SEM1	5154.0
PSMC2	4855.0
PSMA1	4619.0
PSMB9	4456.0
H2AX	4347.0
H3C11	4283.0
H3C1	3952.0
ANAPC16	3918.0
PSMB5	3878.0
PSMD7	3822.0
ORC2	3818.0
H3-3A	3716.0
ANAPC1	3703.0
ANAPC7	3650.0
POLA2	3536.0
CDC26	3378.0
H3-3B	3343.0
CDC23	3069.0
H3C10	2893.0
H4C13	2565.0
PRIM1	2503.0
RPA1	2497.0
ANAPC15	2482.0
MCM4	2201.0
PSMB4	2167.0
PSMD1	2120.0
PSMA2	2110.0
UBE2C	1912.0
PSMD8	1241.0
POLE2	1236.0
PSME2	1076.0
CDK2	744.0
FZR1	635.0
H4C1	603.0
H2AC4	375.0
H2BC5	293.0
MCM10	104.0
H4C6	33.0
H2BC12	15.0
CDC16	-418.0
ANAPC10	-565.0
ORC4	-706.0
PSMD3	-900.0
CDC27	-960.0
ANAPC4	-1152.0
POLE	-1257.0
CDC6	-1321.0
PRIM2	-1328.0
PSMD14	-1456.0
MCM5	-1542.0
PSMD6	-1616.0
PSMC4	-1875.0
H4C2	-1930.0
PSMD9	-2211.0
ORC3	-2289.0
H2BC13	-2522.0
UBE2D1	-2611.0
POLE4	-2735.0
KPNA1	-2867.0
ANAPC5	-2995.0
DBF4	-3157.0
PSMC1	-3824.0
UBC	-3854.0
UBE2E1	-4365.0
ORC5	-4388.0
CDC7	-4394.0
PSMB6	-4529.0
PSMD11	-4817.0
H2BC17	-4820.0
ANAPC2	-5233.0
KPNA6	-5337.0
ANAPC11	-5598.0
CDC45	-5910.0
POLE3	-5927.0
PSMB7	-6036.0
PSMD5	-6141.0
RPA3	-6270.0
MCM7	-6345.0
PSME3	-6565.0
GMNN	-6595.0
KPNB1	-6735.0
H4C4	-6811.0
PSMC6	-6973.0
H2BC1	-7243.0
H2BC3	-7283.0
H4C11	-7768.0
H2BC6	-7780.0
UBE2S	-7971.0
MCM6	-8243.0
H3C6	-9199.0

---

REACTOME_HDACS_DEACETYLATE_HISTONES

REACTOME_HDACS_DEACETYLATE_HISTONES

	548
set	REACTOME_HDACS_DEACETYLATE_HISTONES
setSize	85
pANOVA	0.00105
s.dist	0.206
p.adjustANOVA	0.0352

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC25	11225.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
REST	9962.0
H2BC15	9893.0
H2AC15	9391.0
SAP18	9299.0
H3C8	9291.0
GPS2	9221.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC6	11639.0
H2AC25	11225.0
H2AC18	11198.5
H2AC19	11198.5
H2BC14	11048.0
H2AC14	10639.0
H2BC4	10510.0
H2BC9	10506.5
H3C7	10506.5
H3C4	10448.0
H2BC26	10335.0
H4C16	10207.0
H2BC21	10024.0
H3C2	10000.0
REST	9962.0
H2BC15	9893.0
H2AC15	9391.0
SAP18	9299.0
H3C8	9291.0
GPS2	9221.0
H2BC10	9197.0
H2AC7	8965.5
H2BC7	8965.5
H3C12	8767.0
H2AC8	8539.0
H3C3	8281.0
H2BC11	8255.0
H2AC20	7915.0
H4C8	7890.0
H4C12	7649.0
H4C3	7349.0
SAP30L	7264.0
H2AC21	7263.0
H4C9	7126.0
HDAC1	6863.0
H2BC8	6516.0
ARID4A	6141.0
ARID4B	5817.0
H4C5	5555.0
H2AC12	5178.0
H2AC11	4802.0
HMG20B	4641.0
H3C11	4283.0
H3C1	3952.0
GATAD2B	3344.0
H3C10	2893.0
H4C13	2565.0
TBL1XR1	1474.0
SUDS3	1399.0
KDM1A	1167.0
MTA1	738.0
CHD4	626.0
H4C1	603.0
CHD3	432.0
H2AC4	375.0
H2BC5	293.0
MBD3	142.0
H4C6	33.0
H2BC12	15.0
RBBP4	-35.0
H2AC17	-555.0
NCOR1	-716.0
PHF21A	-756.0
BRMS1	-1736.0
H4C2	-1930.0
HDAC2	-2069.0
H2BC13	-2522.0
H2AC16	-2806.0
MTA2	-3127.0
RCOR1	-3275.0
SAP30	-3642.0
H2AC1	-3797.0
H2AC13	-4028.0
GATAD2A	-4623.0
H2BC17	-4820.0
HDAC3	-5138.0
NCOR2	-6028.0
HDAC10	-6257.0
H4C4	-6811.0
H2BC1	-7243.0
H2BC3	-7283.0
MTA3	-7287.0
H4C11	-7768.0
H2BC6	-7780.0
H3C6	-9199.0

---

REACTOME_PHOSPHOLIPID_METABOLISM

REACTOME_PHOSPHOLIPID_METABOLISM

	136
set	REACTOME_PHOSPHOLIPID_METABOLISM
setSize	201
pANOVA	0.0012
s.dist	-0.132
p.adjustANOVA	0.0395

Top enriched genes

Top 20 genes

GeneID	Gene Rank
INPP5J	-9859
GPD1	-9798
PLA2G2F	-9596
PLD4	-9584
CPNE3	-9061
RAB4A	-9016
PLA2G2E	-8542
GPAT2	-8538
PLA2G10	-8403
SLC44A4	-8396
ARF3	-8103
PLBD1	-8043
ETNPPL	-8025
CHPT1	-7991
SBF1	-7734
PCYT2	-7555
STARD7	-7513
GPD1L	-7504
INPP5F	-7480
PLD6	-7423

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
INPP5J	-9859
GPD1	-9798
PLA2G2F	-9596
PLD4	-9584
CPNE3	-9061
RAB4A	-9016
PLA2G2E	-8542
GPAT2	-8538
PLA2G10	-8403
SLC44A4	-8396
ARF3	-8103
PLBD1	-8043
ETNPPL	-8025
CHPT1	-7991
SBF1	-7734
PCYT2	-7555
STARD7	-7513
GPD1L	-7504
INPP5F	-7480
PLD6	-7423
LPGAT1	-7350
PLAAT3	-7332
PI4KA	-7173
PISD	-6946
AGPAT3	-6892
SLC44A2	-6737
PLEKHA4	-6723
PLA2G4F	-6552
GDPD5	-6532
MTMR4	-6475
ETNK2	-6232
PTPMT1	-6206
LPCAT4	-6025
MIGA2	-5862
CPNE1	-5832
INPP5D	-5740
DGAT2	-5735
LPCAT3	-5716
MFSD2A	-5698
PIP5K1C	-5627
SLC44A1	-5626
PNPLA2	-5610
CPNE7	-5538
GDPD3	-5444
MTMR3	-5439
PITPNM2	-5381
ABHD3	-5341
GPD2	-5333
STARD10	-5317
GPCPD1	-5189
PI4KB	-5175
PEMT	-5163
LPCAT1	-5067
INPP5E	-5060
AGPAT2	-4917
PLA2G5	-4862
PLAAT2	-4829
CDIPT	-4666
PLA2G2A	-4562
DDHD1	-4524
TMEM86B	-4325
PIK3R6	-4137
BCHE	-4097
PIK3R5	-4039
PLA2G15	-4019
CPNE6	-3974
PIK3R2	-3789
PLAAT5	-3439
OSBPL5	-3364
PIK3C2A	-3220
INPPL1	-3184
PIK3C2B	-3064
PITPNM3	-3062
PIP4K2A	-2961
PLEKHA6	-2868
ETNK1	-2802
PIP4K2B	-2718
PI4K2A	-2561
PLEKHA3	-2207
PCTP	-2177
PITPNM1	-2129
OSBPL8	-2103
PLD2	-1977
PLA2G2D	-1919
PLA2G3	-1916
CSNK2A1	-1847
PLA2G4C	-1746
PLA2G4B	-1661
PIK3R3	-1640
LPIN1	-1505
GDPD1	-1502
PLD1	-1368
SYNJ2	-1220
PLA2G6	-1201
LPIN2	-1151
DGAT1	-1142
MBOAT1	-996
MTMR2	-970
PCYT1A	-888
AGPAT5	-686
PI4K2B	-454
MTMR14	-443
RUFY1	-375
PLB1	-296
AGPAT4	-213
PNPLA8	-136
SLC44A3	-131
ABHD4	-73
PLEKHA2	30
PTDSS2	47
MTMR9	127
GPAT4	129
CSNK2A2	162
SYNJ1	188
TNFAIP8L1	462
CHKA	547
INPP5K	565
INPP4A	609
MTMR6	715
LCLAT1	733
ACHE	750
CEPT1	790
MGLL	841
PTEN	982
PTDSS1	1045
CHKB	1058
LIPI	1390
PIK3CB	1504
PTPN13	1551
AGPAT1	1590
PITPNB	1628
ALPI	1716
INPP4B	2076
PLA2G4D	2129
TNFAIP8	2199
PNPLA7	2200
ENPP6	2355
PLD3	2390
MIGA1	2451
PLAAT1	2454
SBF2	2544
PNPLA6	2580
CDS1	2613
CRLS1	2637
MTMR10	2789
SLC44A5	2807
CSNK2B	2924
OSBPL10	2949
TNFAIP8L3	3038
PHOSPHO1	3060
VAC14	3108
RAB14	3134
AGK	3367
CDS2	3387
PLEKHA5	3488
PLA2G1B	3941
ARF1	3951
GNPAT	4146
PLA2G12A	4344
PIK3CD	4402
SELENOI	4498
PLA1A	4601
HADHB	4716
MTMR12	4859
PLA2R1	4875
MBOAT7	4963
PIK3R4	4987
PIP4P1	5307
PGS1	5381
PIK3C3	5576
PIK3CG	5581
PIP4K2C	5750
PIP5K1A	5807
PIK3R1	5836
CHAT	6196
PIK3C2G	6889
FIG4	6995
DDHD2	7025
PIKFYVE	7068
MTMR7	7275
LPIN3	7284
MBOAT2	7372
TPTE2	7857
PNPLA3	7986
PIP5K1B	8082
PLEKHA8	8109
PLA2G4A	8925
LPCAT2	9046
SACM1L	9399
GPAM	9513
PIK3CA	9654
ACP6	9662
RAB5A	9702
PLAAT4	9767
PLEKHA1	9819
HADHA	9828
TNFAIP8L2	9922
LIPH	10076
TPTE	10891
PLA2G4E	10924
GDE1	11150

---

Here is the session info with all the versions of packages used.

sessionInfo()

## R version 4.3.2 (2023-10-31)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.3 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3 
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so;  LAPACK version 3.10.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Etc/UTC
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.3.3                                      
##  [2] GGally_2.2.0                                       
##  [3] ggplot2_3.4.4                                      
##  [4] reshape2_1.4.4                                     
##  [5] gtools_3.9.5                                       
##  [6] tibble_3.2.1                                       
##  [7] dplyr_1.1.4                                        
##  [8] echarts4r_0.4.5                                    
##  [9] png_0.1-8                                          
## [10] gridExtra_2.3                                      
## [11] missMethyl_1.36.0                                  
## [12] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.1 
## [13] beeswarm_0.4.0                                     
## [14] kableExtra_1.3.4                                   
## [15] gplots_3.1.3                                       
## [16] mitch_1.15.0                                       
## [17] tictoc_1.2                                         
## [18] HGNChelper_0.8.1                                   
## [19] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [20] IlluminaHumanMethylation450kmanifest_0.4.0         
## [21] minfi_1.48.0                                       
## [22] bumphunter_1.44.0                                  
## [23] locfit_1.5-9.8                                     
## [24] iterators_1.0.14                                   
## [25] foreach_1.5.2                                      
## [26] Biostrings_2.70.1                                  
## [27] XVector_0.42.0                                     
## [28] SummarizedExperiment_1.32.0                        
## [29] Biobase_2.62.0                                     
## [30] MatrixGenerics_1.14.0                              
## [31] matrixStats_1.2.0                                  
## [32] GenomicRanges_1.54.1                               
## [33] GenomeInfoDb_1.38.2                                
## [34] IRanges_2.36.0                                     
## [35] S4Vectors_0.40.2                                   
## [36] BiocGenerics_0.48.1                                
## [37] eulerr_7.0.0                                       
## [38] limma_3.58.1                                       
## 
## loaded via a namespace (and not attached):
##   [1] splines_4.3.2             later_1.3.2              
##   [3] BiocIO_1.12.0             bitops_1.0-7             
##   [5] filelock_1.0.3            preprocessCore_1.64.0    
##   [7] XML_3.99-0.16             lifecycle_1.0.4          
##   [9] lattice_0.22-5            MASS_7.3-60              
##  [11] base64_2.0.1              scrime_1.3.5             
##  [13] magrittr_2.0.3            sass_0.4.8               
##  [15] rmarkdown_2.25            jquerylib_0.1.4          
##  [17] yaml_2.3.8                httpuv_1.6.13            
##  [19] doRNG_1.8.6               askpass_1.2.0            
##  [21] DBI_1.1.3                 RColorBrewer_1.1-3       
##  [23] abind_1.4-5               zlibbioc_1.48.0          
##  [25] rvest_1.0.3               quadprog_1.5-8           
##  [27] purrr_1.0.2               RCurl_1.98-1.13          
##  [29] rappdirs_0.3.3            GenomeInfoDbData_1.2.11  
##  [31] genefilter_1.84.0         annotate_1.80.0          
##  [33] svglite_2.1.3             DelayedMatrixStats_1.24.0
##  [35] codetools_0.2-19          DelayedArray_0.28.0      
##  [37] xml2_1.3.6                tidyselect_1.2.0         
##  [39] beanplot_1.3.1            BiocFileCache_2.10.1     
##  [41] webshot_0.5.5             illuminaio_0.44.0        
##  [43] GenomicAlignments_1.38.0  jsonlite_1.8.8           
##  [45] multtest_2.58.0           ellipsis_0.3.2           
##  [47] survival_3.5-7            systemfonts_1.0.5        
##  [49] tools_4.3.2               progress_1.2.3           
##  [51] Rcpp_1.0.11               glue_1.6.2               
##  [53] SparseArray_1.2.2         xfun_0.41                
##  [55] HDF5Array_1.30.0          withr_2.5.2              
##  [57] fastmap_1.1.1             rhdf5filters_1.14.1      
##  [59] fansi_1.0.6               openssl_2.1.1            
##  [61] caTools_1.18.2            digest_0.6.33            
##  [63] R6_2.5.1                  mime_0.12                
##  [65] colorspace_2.1-0          biomaRt_2.58.0           
##  [67] RSQLite_2.3.4             utf8_1.2.4               
##  [69] tidyr_1.3.0               generics_0.1.3           
##  [71] data.table_1.14.10        rtracklayer_1.62.0       
##  [73] prettyunits_1.2.0         httr_1.4.7               
##  [75] htmlwidgets_1.6.4         S4Arrays_1.2.0           
##  [77] ggstats_0.5.1             pkgconfig_2.0.3          
##  [79] gtable_0.3.4              blob_1.2.4               
##  [81] siggenes_1.76.0           htmltools_0.5.7          
##  [83] scales_1.3.0              rstudioapi_0.15.0        
##  [85] knitr_1.45                tzdb_0.4.0               
##  [87] rjson_0.2.21              nlme_3.1-163             
##  [89] curl_5.2.0                org.Hs.eg.db_3.18.0      
##  [91] cachem_1.0.8              rhdf5_2.46.1             
##  [93] stringr_1.5.1             KernSmooth_2.23-22       
##  [95] AnnotationDbi_1.64.1      restfulr_0.0.15          
##  [97] GEOquery_2.70.0           pillar_1.9.0             
##  [99] grid_4.3.2                reshape_0.8.9            
## [101] vctrs_0.6.5               promises_1.2.1           
## [103] dbplyr_2.4.0              xtable_1.8-4             
## [105] evaluate_0.23             readr_2.1.4              
## [107] GenomicFeatures_1.54.1    cli_3.6.2                
## [109] compiler_4.3.2            Rsamtools_2.18.0         
## [111] rlang_1.1.2               crayon_1.5.2             
## [113] rngtools_1.5.2            nor1mix_1.3-2            
## [115] mclust_6.0.1              plyr_1.8.9               
## [117] stringi_1.8.3             viridisLite_0.4.2        
## [119] BiocParallel_1.36.0       munsell_0.5.0            
## [121] Matrix_1.6-1.1            hms_1.1.3                
## [123] sparseMatrixStats_1.14.0  bit64_4.0.5              
## [125] Rhdf5lib_1.24.1           KEGGREST_1.42.0          
## [127] statmod_1.5.0             shiny_1.8.0              
## [129] highr_0.10                memoise_2.0.1            
## [131] bslib_0.6.1               bit_4.0.5

END of report