Mitch Report

date generated: 2024-01-18

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch

	x
A1BG	-0.0067578
A1BG-AS1	-0.0087306
A1CF	-0.0016517
A2M	0.0028172
A2M-AS1	0.0109340
A2ML1	0.0032769

Here are some metrics about the input data profile:

Profiling data metrics

	Profile metrics
num_genesets	1654
num_genes_in_profile	22007
duplicated_genes_present	0
num_profile_genes_in_sets	10383
num_profile_genes_not_in_sets	11624

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets: c2.cp.reactome.v2023.1.Hs.symbols.gmt

Gene set metrics

	Gene sets metrics
num_genesets	1654
num_genesets_excluded	365
num_genesets_included	1289

Differential pathway expression

Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

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set	setSize	pANOVA	s.dist	p.adjustANOVA
REACTOME RRNA PROCESSING	192	1.79e-09	0.2520	2.94e-06
REACTOME SELENOAMINO ACID METABOLISM	108	1.54e-08	0.3150	1.27e-05
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY	94	4.52e-08	0.3260	2.40e-05
REACTOME EUKARYOTIC TRANSLATION ELONGATION	87	6.70e-08	0.3350	2.40e-05
REACTOME TRANSLATION	278	7.30e-08	0.1880	2.40e-05
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	105	3.21e-07	0.2890	8.79e-05
REACTOME CELLULAR RESPONSE TO STARVATION	147	6.25e-07	0.2380	1.46e-04
REACTOME EUKARYOTIC TRANSLATION INITIATION	110	5.96e-06	0.2500	1.22e-03
REACTOME INFLUENZA INFECTION	149	8.83e-06	0.2110	1.61e-03
REACTOME NONSENSE MEDIATED DECAY NMD	107	1.83e-05	0.2400	3.00e-03
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY	33	2.52e-05	0.4240	3.76e-03
REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION	31	2.97e-05	-0.4330	4.06e-03
REACTOME SIGNALING BY FGFR1 IN DISEASE	38	5.67e-05	-0.3770	7.16e-03
REACTOME HEMOSTASIS	591	8.18e-05	-0.0948	9.60e-03
REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY	46	1.08e-04	0.3300	1.18e-02
REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	353	1.36e-04	0.1180	1.40e-02
REACTOME METABOLISM OF RNA	675	2.83e-04	0.0819	2.74e-02
REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS	18	4.83e-04	-0.4750	4.20e-02
REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL	58	4.87e-04	0.2650	4.20e-02
REACTOME SIGNALING BY GPCR	673	6.01e-04	-0.0775	4.78e-02
REACTOME KERATINIZATION	210	6.11e-04	0.1370	4.78e-02
REACTOME FORMATION OF THE CORNIFIED ENVELOPE	125	7.68e-04	0.1740	5.73e-02
REACTOME OLFACTORY SIGNALING PATHWAY	348	8.50e-04	0.1040	6.07e-02
REACTOME G ALPHA I SIGNALLING EVENTS	304	1.01e-03	-0.1100	6.82e-02
REACTOME SIGNALING BY FGFR IN DISEASE	62	1.08e-03	-0.2400	6.82e-02
REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT	159	1.08e-03	0.1500	6.82e-02
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS	161	1.56e-03	0.1440	9.47e-02
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION	250	1.61e-03	-0.1160	9.47e-02
REACTOME PI 3K CASCADE FGFR4	19	1.74e-03	-0.4150	9.88e-02
REACTOME SARS COV 2 INFECTION	281	2.57e-03	0.1040	1.41e-01
REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	111	3.16e-03	0.1620	1.67e-01
REACTOME SHC MEDIATED CASCADE FGFR4	19	3.62e-03	-0.3860	1.86e-01
REACTOME LEISHMANIA INFECTION	156	3.85e-03	-0.1340	1.91e-01
REACTOME CHAPERONE MEDIATED AUTOPHAGY	20	4.24e-03	0.3690	2.05e-01
REACTOME HCMV LATE EVENTS	110	4.41e-03	0.1570	2.07e-01
REACTOME SENSORY PERCEPTION OF TASTE	47	5.00e-03	-0.2370	2.26e-01
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	53	5.10e-03	0.2220	2.26e-01
REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R	52	5.24e-03	-0.2240	2.26e-01
REACTOME MITOCHONDRIAL TRANSLATION	93	5.46e-03	0.1670	2.30e-01
REACTOME PI 3K CASCADE FGFR3	17	5.91e-03	-0.3860	2.43e-01
REACTOME SARS COV 2 HOST INTERACTIONS	191	6.66e-03	0.1140	2.67e-01
REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS	418	7.46e-03	-0.0763	2.76e-01
REACTOME RESPIRATORY ELECTRON TRANSPORT	90	7.57e-03	0.1630	2.76e-01
REACTOME PI 3K CASCADE FGFR2	22	7.59e-03	-0.3290	2.76e-01
REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB	5	7.66e-03	-0.6890	2.76e-01
REACTOME ANCHORING FIBRIL FORMATION	13	7.73e-03	0.4270	2.76e-01
REACTOME IRS MEDIATED SIGNALLING	47	8.66e-03	-0.2210	3.03e-01
REACTOME PLATELET CALCIUM HOMEOSTASIS	27	9.22e-03	-0.2890	3.16e-01
REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	32	1.03e-02	-0.2620	3.43e-01
REACTOME DEFECTIVE F9 ACTIVATION	5	1.05e-02	-0.6610	3.43e-01

---

Results (complete table)

Click HERE to show results for all gene sets

Complete results

set	setSize	pANOVA	s.dist	p.adjustANOVA
REACTOME RRNA PROCESSING	192	1.79e-09	0.252000	2.94e-06
REACTOME SELENOAMINO ACID METABOLISM	108	1.54e-08	0.315000	1.27e-05
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY	94	4.52e-08	0.326000	2.40e-05
REACTOME EUKARYOTIC TRANSLATION ELONGATION	87	6.70e-08	0.335000	2.40e-05
REACTOME TRANSLATION	278	7.30e-08	0.188000	2.40e-05
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	105	3.21e-07	0.289000	8.79e-05
REACTOME CELLULAR RESPONSE TO STARVATION	147	6.25e-07	0.238000	1.46e-04
REACTOME EUKARYOTIC TRANSLATION INITIATION	110	5.96e-06	0.250000	1.22e-03
REACTOME INFLUENZA INFECTION	149	8.83e-06	0.211000	1.61e-03
REACTOME NONSENSE MEDIATED DECAY NMD	107	1.83e-05	0.240000	3.00e-03
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY	33	2.52e-05	0.424000	3.76e-03
REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION	31	2.97e-05	-0.433000	4.06e-03
REACTOME SIGNALING BY FGFR1 IN DISEASE	38	5.67e-05	-0.377000	7.16e-03
REACTOME HEMOSTASIS	591	8.18e-05	-0.094800	9.60e-03
REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY	46	1.08e-04	0.330000	1.18e-02
REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	353	1.36e-04	0.118000	1.40e-02
REACTOME METABOLISM OF RNA	675	2.83e-04	0.081900	2.74e-02
REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS	18	4.83e-04	-0.475000	4.20e-02
REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL	58	4.87e-04	0.265000	4.20e-02
REACTOME SIGNALING BY GPCR	673	6.01e-04	-0.077500	4.78e-02
REACTOME KERATINIZATION	210	6.11e-04	0.137000	4.78e-02
REACTOME FORMATION OF THE CORNIFIED ENVELOPE	125	7.68e-04	0.174000	5.73e-02
REACTOME OLFACTORY SIGNALING PATHWAY	348	8.50e-04	0.104000	6.07e-02
REACTOME G ALPHA I SIGNALLING EVENTS	304	1.01e-03	-0.110000	6.82e-02
REACTOME SIGNALING BY FGFR IN DISEASE	62	1.08e-03	-0.240000	6.82e-02
REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT	159	1.08e-03	0.150000	6.82e-02
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS	161	1.56e-03	0.144000	9.47e-02
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION	250	1.61e-03	-0.116000	9.47e-02
REACTOME PI 3K CASCADE FGFR4	19	1.74e-03	-0.415000	9.88e-02
REACTOME SARS COV 2 INFECTION	281	2.57e-03	0.104000	1.41e-01
REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	111	3.16e-03	0.162000	1.67e-01
REACTOME SHC MEDIATED CASCADE FGFR4	19	3.62e-03	-0.386000	1.86e-01
REACTOME LEISHMANIA INFECTION	156	3.85e-03	-0.134000	1.91e-01
REACTOME CHAPERONE MEDIATED AUTOPHAGY	20	4.24e-03	0.369000	2.05e-01
REACTOME HCMV LATE EVENTS	110	4.41e-03	0.157000	2.07e-01
REACTOME SENSORY PERCEPTION OF TASTE	47	5.00e-03	-0.237000	2.26e-01
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	53	5.10e-03	0.222000	2.26e-01
REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R	52	5.24e-03	-0.224000	2.26e-01
REACTOME MITOCHONDRIAL TRANSLATION	93	5.46e-03	0.167000	2.30e-01
REACTOME PI 3K CASCADE FGFR3	17	5.91e-03	-0.386000	2.43e-01
REACTOME SARS COV 2 HOST INTERACTIONS	191	6.66e-03	0.114000	2.67e-01
REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS	418	7.46e-03	-0.076300	2.76e-01
REACTOME RESPIRATORY ELECTRON TRANSPORT	90	7.57e-03	0.163000	2.76e-01
REACTOME PI 3K CASCADE FGFR2	22	7.59e-03	-0.329000	2.76e-01
REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB	5	7.66e-03	-0.689000	2.76e-01
REACTOME ANCHORING FIBRIL FORMATION	13	7.73e-03	0.427000	2.76e-01
REACTOME IRS MEDIATED SIGNALLING	47	8.66e-03	-0.221000	3.03e-01
REACTOME PLATELET CALCIUM HOMEOSTASIS	27	9.22e-03	-0.289000	3.16e-01
REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	32	1.03e-02	-0.262000	3.43e-01
REACTOME DEFECTIVE F9 ACTIVATION	5	1.05e-02	-0.661000	3.43e-01
REACTOME TRNA PROCESSING	105	1.08e-02	0.144000	3.47e-01
REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	39	1.14e-02	-0.234000	3.59e-01
REACTOME SHC MEDIATED CASCADE FGFR3	17	1.18e-02	-0.353000	3.63e-01
REACTOME SIGNALING BY SCF KIT	42	1.19e-02	-0.224000	3.63e-01
REACTOME COMPLEX I BIOGENESIS	49	1.24e-02	0.206000	3.70e-01
REACTOME OPIOID SIGNALLING	89	1.32e-02	-0.152000	3.79e-01
REACTOME TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION	5	1.35e-02	-0.638000	3.79e-01
REACTOME FRS MEDIATED FGFR4 SIGNALING	21	1.36e-02	-0.311000	3.79e-01
REACTOME CARNITINE METABOLISM	13	1.37e-02	-0.395000	3.79e-01
REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	54	1.40e-02	-0.193000	3.79e-01
REACTOME SIGNALING BY PDGFR IN DISEASE	20	1.41e-02	-0.317000	3.79e-01
REACTOME TRANSCRIPTIONAL REGULATION BY MECP2	60	1.50e-02	-0.182000	3.91e-01
REACTOME INSULIN RECEPTOR SIGNALLING CASCADE	53	1.54e-02	-0.192000	3.91e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR4	26	1.54e-02	-0.274000	3.91e-01
REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN	37	1.58e-02	-0.229000	3.91e-01
REACTOME SIGNALING BY INSULIN RECEPTOR	80	1.58e-02	-0.156000	3.91e-01
REACTOME REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA	15	1.60e-02	0.359000	3.91e-01
REACTOME GASTRULATION	49	1.63e-02	-0.198000	3.94e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR4	14	1.67e-02	-0.369000	3.98e-01
REACTOME SARS COV 1 HOST INTERACTIONS	92	1.71e-02	0.144000	3.98e-01
REACTOME G PROTEIN ACTIVATION	24	1.72e-02	-0.281000	3.98e-01
REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING	30	1.76e-02	-0.250000	4.01e-01
REACTOME GP1B IX V ACTIVATION SIGNALLING	11	1.84e-02	-0.410000	4.15e-01
REACTOME REGULATION OF KIT SIGNALING	16	1.99e-02	-0.336000	4.35e-01
REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	18	2.00e-02	0.317000	4.35e-01
REACTOME CA2 PATHWAY	62	2.01e-02	-0.171000	4.35e-01
REACTOME SIGNALING BY ACTIVIN	15	2.14e-02	-0.343000	4.56e-01
REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	12	2.17e-02	-0.383000	4.56e-01
REACTOME FGFR1C LIGAND BINDING AND ACTIVATION	11	2.38e-02	-0.393000	4.90e-01
REACTOME ORGANIC ANION TRANSPORT	5	2.40e-02	0.583000	4.90e-01
REACTOME ACYL CHAIN REMODELLING OF PS	22	2.42e-02	0.278000	4.90e-01
REACTOME NCAM1 INTERACTIONS	41	2.54e-02	0.202000	4.97e-01
REACTOME RHO GTPASE CYCLE	423	2.54e-02	-0.063400	4.97e-01
REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING	12	2.57e-02	0.372000	4.97e-01
REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS	29	2.57e-02	-0.239000	4.97e-01
REACTOME SIGNALING BY FGFR2 IN DISEASE	42	2.64e-02	-0.198000	5.05e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH PI3K	7	2.72e-02	-0.482000	5.10e-01
REACTOME SIGNALING BY ROBO RECEPTORS	206	2.74e-02	0.089200	5.10e-01
REACTOME FGFR3 LIGAND BINDING AND ACTIVATION	12	2.77e-02	-0.367000	5.10e-01
REACTOME INTERFERON SIGNALING	193	2.89e-02	0.091200	5.10e-01
REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	66	2.89e-02	0.155000	5.10e-01
REACTOME PLATELET AGGREGATION PLUG FORMATION	39	2.90e-02	-0.202000	5.10e-01
REACTOME SIGNALING BY FGFR4	40	2.93e-02	-0.199000	5.10e-01
REACTOME SIGNALING BY RECEPTOR TYROSINE KINASES	507	2.98e-02	-0.056400	5.10e-01
REACTOME SMOOTH MUSCLE CONTRACTION	43	2.98e-02	0.191000	5.10e-01
REACTOME ION TRANSPORT BY P TYPE ATPASES	51	3.01e-02	0.176000	5.10e-01
REACTOME GPCR LIGAND BINDING	444	3.01e-02	-0.060000	5.10e-01
REACTOME PI 3K CASCADE FGFR1	21	3.12e-02	-0.271000	5.24e-01
REACTOME DIGESTION	17	3.16e-02	0.301000	5.24e-01
REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	129	3.27e-02	-0.109000	5.37e-01
REACTOME ABACAVIR TRANSMEMBRANE TRANSPORT	5	3.33e-02	0.550000	5.41e-01
REACTOME RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS	5	3.42e-02	-0.547000	5.51e-01
REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION	12	3.63e-02	-0.349000	5.67e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR2	29	3.71e-02	-0.224000	5.67e-01
REACTOME FRS MEDIATED FGFR2 SIGNALING	24	3.75e-02	-0.245000	5.67e-01
REACTOME MRNA EDITING	10	3.76e-02	-0.380000	5.67e-01
REACTOME REGULATION OF NPAS4 MRNA TRANSLATION	9	3.78e-02	-0.400000	5.67e-01
REACTOME CREATION OF C4 AND C2 ACTIVATORS	14	3.80e-02	0.320000	5.67e-01
REACTOME FRS MEDIATED FGFR3 SIGNALING	19	3.86e-02	-0.274000	5.67e-01
REACTOME SIGNALING BY KIT IN DISEASE	20	3.86e-02	-0.267000	5.67e-01
REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING	33	3.87e-02	-0.208000	5.67e-01
REACTOME CHOLESTEROL BIOSYNTHESIS	25	3.89e-02	0.239000	5.67e-01
REACTOME COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES	65	3.94e-02	0.148000	5.67e-01
REACTOME DAP12 SIGNALING	27	3.97e-02	-0.229000	5.67e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1	229	3.97e-02	-0.078900	5.67e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR3	24	4.01e-02	-0.242000	5.68e-01
REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX	36	4.13e-02	-0.197000	5.75e-01
REACTOME POST TRANSCRIPTIONAL SILENCING BY SMALL RNAS	7	4.13e-02	-0.445000	5.75e-01
REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS	299	4.17e-02	-0.068500	5.75e-01
REACTOME ACTIVATION OF BH3 ONLY PROTEINS	30	4.24e-02	-0.214000	5.78e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1	25	4.27e-02	-0.234000	5.78e-01
REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING	28	4.30e-02	-0.221000	5.78e-01
REACTOME SCAVENGING BY CLASS B RECEPTORS	6	4.39e-02	-0.475000	5.78e-01
REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS	101	4.46e-02	-0.116000	5.78e-01
REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	12	4.47e-02	-0.335000	5.78e-01
REACTOME GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION	42	4.49e-02	-0.179000	5.78e-01
REACTOME RHOF GTPASE CYCLE	40	4.52e-02	-0.183000	5.78e-01
REACTOME SIGNALING BY NUCLEAR RECEPTORS	283	4.54e-02	-0.069100	5.78e-01
REACTOME SENSORY PERCEPTION	555	4.56e-02	0.049600	5.78e-01
REACTOME FCERI MEDIATED CA 2 MOBILIZATION	30	4.57e-02	-0.211000	5.78e-01
REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION	11	4.64e-02	-0.347000	5.81e-01
REACTOME CD163 MEDIATING AN ANTI INFLAMMATORY RESPONSE	9	4.74e-02	-0.382000	5.86e-01
REACTOME EFFECTS OF PIP2 HYDROLYSIS	26	4.75e-02	-0.225000	5.86e-01
REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	16	4.86e-02	-0.285000	5.96e-01
REACTOME EXTRACELLULAR MATRIX ORGANIZATION	291	4.94e-02	0.067000	6.01e-01
REACTOME TRANSPORT OF ORGANIC ANIONS	10	5.01e-02	0.358000	6.04e-01
REACTOME CELLULAR RESPONSES TO STIMULI	779	5.09e-02	0.041100	6.04e-01
REACTOME METALLOPROTEASE DUBS	36	5.11e-02	0.188000	6.04e-01
REACTOME UNFOLDED PROTEIN RESPONSE UPR	88	5.12e-02	0.120000	6.04e-01
REACTOME SHC MEDIATED CASCADE FGFR1	21	5.19e-02	-0.245000	6.06e-01
REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	38	5.20e-02	0.182000	6.06e-01
REACTOME DISEASES OF GLYCOSYLATION	137	5.27e-02	0.095900	6.10e-01
REACTOME SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA PHE	6	5.34e-02	0.455000	6.14e-01
REACTOME HDL CLEARANCE	5	5.41e-02	-0.497000	6.17e-01
REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES	34	5.56e-02	-0.190000	6.17e-01
REACTOME NEUTROPHIL DEGRANULATION	460	5.58e-02	-0.052000	6.17e-01
REACTOME CLEC7A INFLAMMASOME PATHWAY	6	5.61e-02	-0.450000	6.17e-01
REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3	679	5.62e-02	-0.043000	6.17e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH CDC42	19	5.65e-02	-0.253000	6.17e-01
REACTOME MRNA EDITING C TO U CONVERSION	8	5.68e-02	-0.389000	6.17e-01
REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL	41	5.69e-02	0.172000	6.17e-01
REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS	14	5.72e-02	-0.294000	6.17e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2	17	5.76e-02	-0.266000	6.18e-01
REACTOME SARS COV INFECTIONS	392	6.19e-02	0.054900	6.59e-01
REACTOME CROSSLINKING OF COLLAGEN FIBRILS	16	6.23e-02	0.269000	6.59e-01
REACTOME GRB7 EVENTS IN ERBB2 SIGNALING	5	6.28e-02	-0.481000	6.59e-01
REACTOME LATE ENDOSOMAL MICROAUTOPHAGY	33	6.33e-02	0.187000	6.59e-01
REACTOME HCMV INFECTION	152	6.35e-02	0.087200	6.59e-01
REACTOME ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION	16	6.38e-02	-0.268000	6.59e-01
REACTOME LAMININ INTERACTIONS	28	6.55e-02	0.201000	6.67e-01
REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	160	6.59e-02	-0.084300	6.67e-01
REACTOME SIGNALING BY NODAL	20	6.60e-02	-0.237000	6.67e-01
REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS	66	6.62e-02	0.131000	6.67e-01
REACTOME TRANSPORT OF SMALL MOLECULES	697	6.78e-02	0.040600	6.70e-01
REACTOME PLATELET HOMEOSTASIS	85	6.79e-02	-0.115000	6.70e-01
REACTOME SUMOYLATION OF INTRACELLULAR RECEPTORS	29	6.82e-02	-0.196000	6.70e-01
REACTOME RAP1 SIGNALLING	16	6.85e-02	-0.263000	6.70e-01
REACTOME GERM LAYER FORMATION AT GASTRULATION	17	6.86e-02	-0.255000	6.70e-01
REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	80	6.92e-02	0.118000	6.70e-01
REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION	32	6.95e-02	-0.185000	6.70e-01
REACTOME VITAMINS	6	6.98e-02	-0.427000	6.70e-01
REACTOME PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING	11	7.03e-02	0.315000	6.71e-01
REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	63	7.07e-02	-0.132000	6.71e-01
REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE	71	7.14e-02	-0.124000	6.74e-01
REACTOME REGULATION OF SIGNALING BY NODAL	9	7.22e-02	-0.346000	6.74e-01
REACTOME DISORDERS OF TRANSMEMBRANE TRANSPORTERS	170	7.24e-02	0.079900	6.74e-01
REACTOME COLLAGEN FORMATION	88	7.28e-02	0.111000	6.74e-01
REACTOME NUCLEOTIDE SALVAGE	21	7.44e-02	-0.225000	6.74e-01
REACTOME RRNA PROCESSING IN THE MITOCHONDRION	9	7.44e-02	0.343000	6.74e-01
REACTOME KILLING MECHANISMS	11	7.45e-02	-0.311000	6.74e-01
REACTOME JOSEPHIN DOMAIN DUBS	11	7.47e-02	0.310000	6.74e-01
REACTOME COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC	52	7.50e-02	-0.143000	6.74e-01
REACTOME SIGNALING BY FGFR3	39	7.53e-02	-0.165000	6.74e-01
REACTOME NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION	193	7.55e-02	-0.074200	6.74e-01
REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT	236	7.65e-02	0.066900	6.79e-01
REACTOME INTERLEUKIN 1 PROCESSING	9	7.69e-02	-0.341000	6.79e-01
REACTOME NEGATIVE REGULATION OF ACTIVITY OF TFAP2 AP 2 FAMILY TRANSCRIPTION FACTORS	10	7.74e-02	-0.322000	6.79e-01
REACTOME FORMATION OF AXIAL MESODERM	14	7.77e-02	-0.272000	6.79e-01
REACTOME SIGNALING BY RETINOIC ACID	41	7.83e-02	-0.159000	6.81e-01
REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION	26	7.88e-02	-0.199000	6.81e-01
REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	15	8.02e-02	0.261000	6.90e-01
REACTOME MAPK FAMILY SIGNALING CASCADES	314	8.06e-02	-0.057300	6.90e-01
REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS	42	8.17e-02	0.155000	6.90e-01
REACTOME DIGESTION OF DIETARY CARBOHYDRATE	6	8.20e-02	0.410000	6.90e-01
REACTOME LINOLEIC ACID LA METABOLISM	7	8.23e-02	0.379000	6.90e-01
REACTOME INTERLEUKIN 2 SIGNALING	11	8.23e-02	-0.303000	6.90e-01
REACTOME REGULATION OF MECP2 EXPRESSION AND ACTIVITY	30	8.43e-02	-0.182000	6.97e-01
REACTOME REGULATION OF RUNX1 EXPRESSION AND ACTIVITY	17	8.43e-02	-0.242000	6.97e-01
REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS	19	8.46e-02	-0.229000	6.97e-01
REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING	29	8.50e-02	-0.185000	6.97e-01
REACTOME UNWINDING OF DNA	12	8.55e-02	0.287000	6.97e-01
REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE	52	8.58e-02	0.138000	6.97e-01
REACTOME RHO GTPASES ACTIVATE IQGAPS	31	8.63e-02	-0.178000	6.98e-01
REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	15	8.71e-02	-0.255000	6.99e-01
REACTOME CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION	11	8.74e-02	-0.298000	6.99e-01
REACTOME SUMO IS CONJUGATED TO E1 UBA2 SAE1	5	8.82e-02	-0.440000	6.99e-01
REACTOME REDUCTION OF CYTOSOLIC CA LEVELS	11	8.92e-02	-0.296000	6.99e-01
REACTOME INTERLEUKIN 15 SIGNALING	13	8.96e-02	-0.272000	6.99e-01
REACTOME RAC1 GTPASE CYCLE	172	9.06e-02	-0.074800	6.99e-01
REACTOME SARS COV 2 ACTIVATES MODULATES INNATE AND ADAPTIVE IMMUNE RESPONSES	118	9.06e-02	0.090200	6.99e-01
REACTOME RHO GTPASES ACTIVATE NADPH OXIDASES	21	9.09e-02	-0.213000	6.99e-01
REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	32	9.12e-02	-0.173000	6.99e-01
REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER	77	9.16e-02	-0.111000	6.99e-01
REACTOME SCAVENGING BY CLASS A RECEPTORS	19	9.17e-02	0.223000	6.99e-01
REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	15	9.19e-02	-0.251000	6.99e-01
REACTOME INTERLEUKIN 36 PATHWAY	7	9.20e-02	0.368000	6.99e-01
REACTOME NR1H2 AND NR1H3 MEDIATED SIGNALING	46	9.24e-02	-0.143000	6.99e-01
REACTOME ERYTHROPOIETIN ACTIVATES STAT5	7	9.32e-02	-0.366000	7.02e-01
REACTOME INTERLEUKIN 9 SIGNALING	7	9.42e-02	-0.365000	7.02e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH RAS	9	9.44e-02	-0.322000	7.02e-01
REACTOME DIGESTION AND ABSORPTION	22	9.47e-02	0.206000	7.02e-01
REACTOME CA2 ACTIVATED K CHANNELS	9	9.49e-02	0.322000	7.02e-01
REACTOME PARASITE INFECTION	57	9.64e-02	-0.127000	7.04e-01
REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS	5	9.68e-02	0.429000	7.04e-01
REACTOME NEF AND SIGNAL TRANSDUCTION	8	9.78e-02	-0.338000	7.04e-01
REACTOME METABOLISM OF INGESTED SEMET SEC MESEC INTO H2SE	7	9.80e-02	0.361000	7.04e-01
REACTOME SARS COV 1 INFECTION	136	9.84e-02	0.082100	7.04e-01
REACTOME FGFRL1 MODULATION OF FGFR1 SIGNALING	13	9.86e-02	-0.265000	7.04e-01
REACTOME HDR THROUGH MMEJ ALT NHEJ	12	9.87e-02	0.275000	7.04e-01
REACTOME ADAPTIVE IMMUNE SYSTEM	729	9.91e-02	-0.035900	7.04e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS	14	9.94e-02	-0.254000	7.04e-01
REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	52	9.96e-02	0.132000	7.04e-01
REACTOME G PROTEIN BETA GAMMA SIGNALLING	30	1.01e-01	-0.173000	7.04e-01
REACTOME UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN	6	1.01e-01	0.387000	7.04e-01
REACTOME G PROTEIN MEDIATED EVENTS	53	1.01e-01	-0.130000	7.04e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH METHYLATION	19	1.02e-01	0.217000	7.04e-01
REACTOME ACYL CHAIN REMODELLING OF PI	17	1.02e-01	0.229000	7.04e-01
REACTOME NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	11	1.03e-01	0.284000	7.04e-01
REACTOME TRNA PROCESSING IN THE NUCLEUS	58	1.03e-01	0.124000	7.04e-01
REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING	32	1.03e-01	-0.167000	7.04e-01
REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	93	1.04e-01	-0.097500	7.04e-01
REACTOME ONCOGENIC MAPK SIGNALING	79	1.04e-01	-0.106000	7.04e-01
REACTOME AMYLOID FIBER FORMATION	102	1.04e-01	0.093100	7.04e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION	89	1.05e-01	0.099300	7.06e-01
REACTOME REGULATION OF PTEN MRNA TRANSLATION	9	1.06e-01	-0.311000	7.06e-01
REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION	62	1.06e-01	0.119000	7.06e-01
REACTOME REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS	7	1.07e-01	-0.352000	7.06e-01
REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH	62	1.07e-01	0.118000	7.06e-01
REACTOME ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS	7	1.07e-01	-0.352000	7.06e-01
REACTOME HDL REMODELING	10	1.08e-01	-0.293000	7.07e-01
REACTOME SCAVENGING BY CLASS F RECEPTORS	6	1.08e-01	0.378000	7.07e-01
REACTOME SIGNALING BY ALK IN CANCER	53	1.09e-01	-0.127000	7.07e-01
REACTOME GLUTAMATE AND GLUTAMINE METABOLISM	13	1.10e-01	-0.256000	7.14e-01
REACTOME HATS ACETYLATE HISTONES	129	1.11e-01	0.081300	7.16e-01
REACTOME PERK REGULATES GENE EXPRESSION	31	1.11e-01	0.165000	7.16e-01
REACTOME RAC2 GTPASE CYCLE	81	1.13e-01	-0.102000	7.17e-01
REACTOME CYP2E1 REACTIONS	10	1.13e-01	-0.289000	7.17e-01
REACTOME PI3K AKT SIGNALING IN CANCER	103	1.15e-01	-0.089900	7.17e-01
REACTOME MAP2K AND MAPK ACTIVATION	38	1.15e-01	-0.148000	7.17e-01
REACTOME BETA CATENIN INDEPENDENT WNT SIGNALING	145	1.15e-01	-0.075700	7.17e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES	10	1.16e-01	0.287000	7.17e-01
REACTOME CONDENSATION OF PROMETAPHASE CHROMOSOMES	11	1.16e-01	0.274000	7.17e-01
REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	15	1.16e-01	-0.234000	7.17e-01
REACTOME FRS MEDIATED FGFR1 SIGNALING	23	1.16e-01	-0.189000	7.17e-01
REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	24	1.16e-01	-0.185000	7.17e-01
REACTOME G2 M CHECKPOINTS	162	1.17e-01	0.071300	7.17e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL	15	1.17e-01	-0.234000	7.17e-01
REACTOME ROLE OF ABL IN ROBO SLIT SIGNALING	8	1.17e-01	-0.320000	7.17e-01
REACTOME G ALPHA S SIGNALLING EVENTS	155	1.17e-01	-0.072900	7.17e-01
REACTOME O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS	38	1.19e-01	0.146000	7.17e-01
REACTOME CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA	63	1.19e-01	0.114000	7.17e-01
REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION	19	1.19e-01	0.206000	7.17e-01
REACTOME CELL CYCLE CHECKPOINTS	284	1.20e-01	0.053700	7.17e-01
REACTOME CELL CYCLE MITOTIC	539	1.20e-01	0.039200	7.17e-01
REACTOME MET ACTIVATES PTK2 SIGNALING	30	1.20e-01	0.164000	7.17e-01
REACTOME ABACAVIR ADME	9	1.21e-01	0.299000	7.18e-01
REACTOME CITRIC ACID CYCLE TCA CYCLE	21	1.23e-01	0.195000	7.24e-01
REACTOME RA BIOSYNTHESIS PATHWAY	22	1.23e-01	-0.190000	7.24e-01
REACTOME FORMATION OF APOPTOSOME	10	1.23e-01	-0.281000	7.24e-01
REACTOME CRISTAE FORMATION	27	1.23e-01	0.171000	7.24e-01
REACTOME CONDENSATION OF PROPHASE CHROMOSOMES	66	1.24e-01	0.109000	7.25e-01
REACTOME PASSIVE TRANSPORT BY AQUAPORINS	13	1.26e-01	0.245000	7.34e-01
REACTOME SIGNAL AMPLIFICATION	33	1.27e-01	-0.154000	7.34e-01
REACTOME SLC TRANSPORTER DISORDERS	94	1.27e-01	0.091100	7.34e-01
REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS	83	1.29e-01	-0.096500	7.39e-01
REACTOME NEURONAL SYSTEM	388	1.29e-01	-0.044900	7.39e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY DVL INTERACTING PROTEINS	5	1.30e-01	-0.391000	7.43e-01
REACTOME PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS	21	1.31e-01	-0.191000	7.43e-01
REACTOME TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS	82	1.31e-01	0.096500	7.43e-01
REACTOME G ALPHA Q SIGNALLING EVENTS	206	1.31e-01	-0.061000	7.43e-01
REACTOME FBXW7 MUTANTS AND NOTCH1 IN CANCER	5	1.32e-01	-0.389000	7.43e-01
REACTOME HCMV EARLY EVENTS	128	1.32e-01	0.077000	7.43e-01
REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	16	1.33e-01	0.217000	7.43e-01
REACTOME DISEASES OF METABOLISM	237	1.33e-01	0.056600	7.43e-01
REACTOME CYTOCHROME C MEDIATED APOPTOTIC RESPONSE	12	1.34e-01	-0.250000	7.46e-01
REACTOME TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS	36	1.34e-01	-0.144000	7.46e-01
REACTOME PYRIMIDINE CATABOLISM	12	1.36e-01	-0.248000	7.53e-01
REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	20	1.38e-01	0.191000	7.57e-01
REACTOME OVARIAN TUMOR DOMAIN PROTEASES	36	1.39e-01	0.143000	7.57e-01
REACTOME SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS	43	1.39e-01	-0.130000	7.57e-01
REACTOME CD28 CO STIMULATION	32	1.39e-01	-0.151000	7.57e-01
REACTOME RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY	14	1.39e-01	0.228000	7.57e-01
REACTOME SYNTHESIS OF LIPOXINS LX	6	1.41e-01	-0.347000	7.57e-01
REACTOME CALCITONIN LIKE LIGAND RECEPTORS	10	1.41e-01	-0.269000	7.57e-01
REACTOME BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA	17	1.41e-01	0.206000	7.57e-01
REACTOME PKMTS METHYLATE HISTONE LYSINES	64	1.41e-01	-0.106000	7.57e-01
REACTOME COSTIMULATION BY THE CD28 FAMILY	64	1.43e-01	-0.106000	7.62e-01
REACTOME SIGNALING BY ERYTHROPOIETIN	25	1.44e-01	-0.169000	7.67e-01
REACTOME FC EPSILON RECEPTOR FCERI SIGNALING	127	1.45e-01	-0.075000	7.67e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K	12	1.46e-01	-0.243000	7.67e-01
REACTOME TRANSPORT OF RCBL WITHIN THE BODY	8	1.46e-01	-0.297000	7.67e-01
REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	111	1.46e-01	-0.079900	7.67e-01
REACTOME SHC RELATED EVENTS TRIGGERED BY IGF1R	9	1.46e-01	-0.280000	7.67e-01
REACTOME GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION	30	1.47e-01	0.153000	7.70e-01
REACTOME RHOBTB2 GTPASE CYCLE	22	1.48e-01	-0.178000	7.70e-01
REACTOME FCERI MEDIATED MAPK ACTIVATION	32	1.49e-01	-0.147000	7.74e-01
REACTOME ROBO RECEPTORS BIND AKAP5	9	1.49e-01	-0.278000	7.74e-01
REACTOME SEMAPHORIN INTERACTIONS	61	1.52e-01	0.106000	7.84e-01
REACTOME HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS	7	1.52e-01	-0.312000	7.84e-01
REACTOME INFECTIOUS DISEASE	910	1.53e-01	0.027900	7.85e-01
REACTOME CELLULAR RESPONSE TO HEAT STRESS	99	1.54e-01	0.083000	7.85e-01
REACTOME MET ACTIVATES RAP1 AND RAC1	11	1.55e-01	-0.248000	7.85e-01
REACTOME FOLDING OF ACTIN BY CCT TRIC	10	1.56e-01	0.259000	7.85e-01
REACTOME GPVI MEDIATED ACTIVATION CASCADE	35	1.56e-01	-0.139000	7.85e-01
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION	138	1.56e-01	-0.069900	7.85e-01
REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION	74	1.58e-01	-0.094800	7.85e-01
REACTOME EXTRA NUCLEAR ESTROGEN SIGNALING	74	1.59e-01	-0.094800	7.85e-01
REACTOME FRUCTOSE CATABOLISM	5	1.59e-01	0.364000	7.85e-01
REACTOME SUMOYLATION OF TRANSCRIPTION FACTORS	20	1.59e-01	-0.182000	7.85e-01
REACTOME SIGNALING BY WNT	318	1.60e-01	-0.045800	7.85e-01
REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	46	1.60e-01	0.120000	7.85e-01
REACTOME BASE EXCISION REPAIR AP SITE FORMATION	59	1.60e-01	0.106000	7.85e-01
REACTOME CRMPS IN SEMA3A SIGNALING	15	1.61e-01	0.209000	7.85e-01
REACTOME DARPP 32 EVENTS	24	1.61e-01	-0.165000	7.85e-01
REACTOME SUMOYLATION	179	1.62e-01	-0.060600	7.85e-01
REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	78	1.62e-01	0.091500	7.85e-01
REACTOME SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS	12	1.62e-01	-0.233000	7.85e-01
REACTOME VITAMIN D CALCIFEROL METABOLISM	12	1.63e-01	-0.232000	7.85e-01
REACTOME RECEPTOR MEDIATED MITOPHAGY	10	1.63e-01	-0.255000	7.85e-01
REACTOME CALCINEURIN ACTIVATES NFAT	9	1.64e-01	-0.268000	7.85e-01
REACTOME TYROSINE CATABOLISM	5	1.64e-01	0.360000	7.85e-01
REACTOME MATURATION OF PROTEIN 3A	9	1.64e-01	-0.268000	7.85e-01
REACTOME SIGNALING BY FGFR2	72	1.65e-01	-0.094700	7.85e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1	31	1.65e-01	-0.144000	7.85e-01
REACTOME CA DEPENDENT EVENTS	36	1.65e-01	-0.134000	7.85e-01
REACTOME APOPTOTIC FACTOR MEDIATED RESPONSE	19	1.66e-01	-0.184000	7.85e-01
REACTOME IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN	5	1.66e-01	0.358000	7.85e-01
REACTOME MINERALOCORTICOID BIOSYNTHESIS	6	1.66e-01	-0.326000	7.85e-01
REACTOME MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS	17	1.68e-01	-0.193000	7.90e-01
REACTOME DISEASES OF MITOTIC CELL CYCLE	37	1.69e-01	-0.131000	7.90e-01
REACTOME PYRIMIDINE SALVAGE	10	1.69e-01	-0.251000	7.90e-01
REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	19	1.70e-01	-0.182000	7.90e-01
REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS	188	1.70e-01	-0.058000	7.90e-01
REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS	16	1.72e-01	0.197000	7.91e-01
REACTOME DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B	7	1.72e-01	-0.298000	7.91e-01
REACTOME SIGNALING BY FLT3 FUSION PROTEINS	19	1.72e-01	-0.181000	7.91e-01
REACTOME NERVOUS SYSTEM DEVELOPMENT	552	1.72e-01	0.034000	7.91e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12	22	1.73e-01	-0.168000	7.91e-01
REACTOME NADE MODULATES DEATH SIGNALLING	5	1.73e-01	0.352000	7.91e-01
REACTOME HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR IN THE PRESENCE OF LIGAND	55	1.74e-01	-0.106000	7.91e-01
REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	15	1.75e-01	0.202000	7.91e-01
REACTOME FGFR2 LIGAND BINDING AND ACTIVATION	19	1.75e-01	-0.180000	7.91e-01
REACTOME NEPHRIN FAMILY INTERACTIONS	22	1.76e-01	-0.167000	7.91e-01
REACTOME P75NTR REGULATES AXONOGENESIS	9	1.76e-01	0.261000	7.91e-01
REACTOME GLUTATHIONE CONJUGATION	33	1.76e-01	0.136000	7.91e-01
REACTOME ANTIMICROBIAL PEPTIDES	76	1.76e-01	0.089700	7.91e-01
REACTOME RRNA MODIFICATION IN THE MITOCHONDRION	6	1.78e-01	0.317000	7.99e-01
REACTOME COLLAGEN CHAIN TRIMERIZATION	42	1.82e-01	0.119000	8.12e-01
REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES	7	1.83e-01	-0.290000	8.12e-01
REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	14	1.84e-01	0.205000	8.12e-01
REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	11	1.85e-01	-0.231000	8.12e-01
REACTOME CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE	49	1.87e-01	0.109000	8.12e-01
REACTOME OAS ANTIVIRAL RESPONSE	8	1.87e-01	0.269000	8.12e-01
REACTOME ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS	11	1.87e-01	-0.230000	8.12e-01
REACTOME INTEGRIN SIGNALING	27	1.88e-01	-0.146000	8.12e-01
REACTOME HDACS DEACETYLATE HISTONES	85	1.88e-01	0.082500	8.12e-01
REACTOME RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION	6	1.88e-01	-0.310000	8.12e-01
REACTOME ACYL CHAIN REMODELLING OF PG	18	1.88e-01	0.179000	8.12e-01
REACTOME RHOD GTPASE CYCLE	49	1.89e-01	-0.108000	8.12e-01
REACTOME PROCESSING OF SMDT1	16	1.89e-01	0.190000	8.12e-01
REACTOME DEFECTIVE GALNT3 CAUSES HFTC	16	1.90e-01	0.189000	8.12e-01
REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS	43	1.90e-01	-0.116000	8.12e-01
REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES	37	1.90e-01	0.125000	8.12e-01
REACTOME METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION	15	1.90e-01	-0.196000	8.12e-01
REACTOME VOLTAGE GATED POTASSIUM CHANNELS	42	1.90e-01	-0.117000	8.12e-01
REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS	27	1.92e-01	-0.145000	8.12e-01
REACTOME SIGNALING BY FGFR4 IN DISEASE	11	1.92e-01	-0.227000	8.12e-01
REACTOME SIGNALING BY NOTCH1	69	1.93e-01	-0.090700	8.12e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING	5	1.93e-01	-0.336000	8.12e-01
REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM	23	1.94e-01	0.157000	8.12e-01
REACTOME DAP12 INTERACTIONS	37	1.94e-01	-0.123000	8.12e-01
REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	32	1.94e-01	0.133000	8.12e-01
REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	16	1.94e-01	0.187000	8.12e-01
REACTOME RAC3 GTPASE CYCLE	85	1.95e-01	-0.081300	8.12e-01
REACTOME STRIATED MUSCLE CONTRACTION	35	1.95e-01	-0.126000	8.12e-01
REACTOME MYOGENESIS	29	1.96e-01	-0.139000	8.13e-01
REACTOME ECM PROTEOGLYCANS	73	1.98e-01	0.087200	8.13e-01
REACTOME MODULATION BY MTB OF HOST IMMUNE SYSTEM	6	1.98e-01	0.304000	8.13e-01
REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION	60	1.98e-01	0.096100	8.13e-01
REACTOME SIGNALING BY MST1	5	1.99e-01	-0.332000	8.13e-01
REACTOME ALPHA OXIDATION OF PHYTANATE	6	1.99e-01	-0.302000	8.13e-01
REACTOME APOPTOSIS	173	1.99e-01	-0.056500	8.13e-01
REACTOME DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS	14	2.00e-01	-0.198000	8.13e-01
REACTOME SODIUM COUPLED PHOSPHATE COTRANSPORTERS	5	2.01e-01	0.330000	8.16e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX	91	2.01e-01	0.077500	8.16e-01
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES	255	2.02e-01	-0.046400	8.17e-01
REACTOME TRNA AMINOACYLATION	40	2.05e-01	0.116000	8.22e-01
REACTOME BH3 ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI APOPTOTIC BCL 2 MEMBERS	9	2.05e-01	-0.244000	8.22e-01
REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	134	2.05e-01	0.063400	8.22e-01
REACTOME ACYL CHAIN REMODELLING OF PE	29	2.06e-01	0.136000	8.25e-01
REACTOME NGF INDEPENDANT TRKA ACTIVATION	5	2.07e-01	-0.326000	8.25e-01
REACTOME INTERFERON ALPHA BETA SIGNALING	70	2.07e-01	0.087200	8.25e-01
REACTOME ACTIVATION OF RAC1	12	2.07e-01	-0.210000	8.25e-01
REACTOME HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS	9	2.08e-01	-0.242000	8.25e-01
REACTOME RECYCLING PATHWAY OF L1	43	2.09e-01	-0.111000	8.26e-01
REACTOME NECTIN NECL TRANS HETERODIMERIZATION	7	2.10e-01	0.274000	8.28e-01
REACTOME FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS	8	2.11e-01	-0.255000	8.28e-01
REACTOME RHOG GTPASE CYCLE	71	2.11e-01	-0.085800	8.28e-01
REACTOME GABA RECEPTOR ACTIVATION	57	2.11e-01	-0.095700	8.28e-01
REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	51	2.12e-01	-0.101000	8.28e-01
REACTOME SIGNALING BY HIPPO	19	2.13e-01	0.165000	8.28e-01
REACTOME ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA	15	2.13e-01	-0.186000	8.28e-01
REACTOME M PHASE	398	2.13e-01	0.036400	8.28e-01
REACTOME RECYCLING OF EIF2 GDP	7	2.15e-01	0.271000	8.32e-01
REACTOME RHO GTPASES ACTIVATE CIT	19	2.15e-01	-0.164000	8.32e-01
REACTOME TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE	10	2.17e-01	0.226000	8.35e-01
REACTOME REACTIONS SPECIFIC TO THE COMPLEX N GLYCAN SYNTHESIS PATHWAY	10	2.18e-01	0.225000	8.37e-01
REACTOME SARS COV 2 TARGETS PDZ PROTEINS IN CELL CELL JUNCTION	5	2.18e-01	-0.318000	8.38e-01
REACTOME LIPOPHAGY	9	2.20e-01	0.236000	8.42e-01
REACTOME DNA DOUBLE STRAND BREAK RESPONSE	74	2.21e-01	0.082300	8.43e-01
REACTOME OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS	8	2.23e-01	-0.249000	8.47e-01
REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION	84	2.23e-01	0.076900	8.47e-01
REACTOME MITOCHONDRIAL BIOGENESIS	87	2.24e-01	0.075500	8.48e-01
REACTOME FCGR3A MEDIATED IL10 SYNTHESIS	36	2.27e-01	-0.116000	8.50e-01
REACTOME SUMO IS PROTEOLYTICALLY PROCESSED	6	2.28e-01	-0.284000	8.50e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION	45	2.28e-01	-0.104000	8.50e-01
REACTOME BIOSYNTHESIS OF MARESINS	8	2.29e-01	-0.246000	8.50e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS	7	2.29e-01	-0.262000	8.50e-01
REACTOME BUDDING AND MATURATION OF HIV VIRION	28	2.30e-01	0.131000	8.50e-01
REACTOME PROCESSING OF DNA DOUBLE STRAND BREAK ENDS	93	2.30e-01	0.072000	8.50e-01
REACTOME HSF1 DEPENDENT TRANSACTIVATION	37	2.30e-01	0.114000	8.50e-01
REACTOME TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE	20	2.30e-01	-0.155000	8.50e-01
REACTOME PROGRAMMED CELL DEATH	204	2.31e-01	-0.048700	8.50e-01
REACTOME RELAXIN RECEPTORS	8	2.31e-01	-0.244000	8.50e-01
REACTOME CDC42 GTPASE CYCLE	144	2.31e-01	-0.057800	8.50e-01
REACTOME ACTIVATION OF NIMA KINASES NEK9 NEK6 NEK7	7	2.32e-01	-0.261000	8.50e-01
REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	17	2.32e-01	0.167000	8.50e-01
REACTOME FGFR3B LIGAND BINDING AND ACTIVATION	7	2.34e-01	-0.260000	8.50e-01
REACTOME TYSND1 CLEAVES PEROXISOMAL PROTEINS	7	2.34e-01	-0.259000	8.50e-01
REACTOME AZATHIOPRINE ADME	22	2.35e-01	0.146000	8.50e-01
REACTOME THE PHOTOTRANSDUCTION CASCADE	32	2.36e-01	-0.121000	8.50e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE	11	2.36e-01	-0.207000	8.50e-01
REACTOME FLT3 SIGNALING	38	2.36e-01	-0.111000	8.50e-01
REACTOME SYNTHESIS OF PC	27	2.37e-01	-0.132000	8.50e-01
REACTOME CD28 DEPENDENT VAV1 PATHWAY	11	2.37e-01	-0.206000	8.50e-01
REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS	28	2.37e-01	-0.129000	8.50e-01
REACTOME ESR MEDIATED SIGNALING	210	2.38e-01	-0.047300	8.50e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE	5	2.38e-01	-0.305000	8.50e-01
REACTOME HIV LIFE CYCLE	145	2.39e-01	0.056700	8.50e-01
REACTOME XENOBIOTICS	22	2.40e-01	-0.145000	8.50e-01
REACTOME DAG AND IP3 SIGNALING	40	2.40e-01	-0.107000	8.50e-01
REACTOME RAF ACTIVATION	33	2.41e-01	-0.118000	8.50e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES	11	2.41e-01	0.204000	8.50e-01
REACTOME ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA	9	2.41e-01	-0.226000	8.50e-01
REACTOME COENZYME A BIOSYNTHESIS	8	2.41e-01	0.239000	8.50e-01
REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	31	2.42e-01	0.121000	8.50e-01
REACTOME ESTROGEN BIOSYNTHESIS	6	2.42e-01	0.276000	8.50e-01
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	263	2.42e-01	0.041900	8.50e-01
REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	12	2.44e-01	0.194000	8.51e-01
REACTOME PROTEIN FOLDING	96	2.44e-01	-0.068900	8.51e-01
REACTOME O LINKED GLYCOSYLATION	109	2.46e-01	0.064400	8.54e-01
REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	29	2.47e-01	-0.124000	8.54e-01
REACTOME ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS	17	2.47e-01	-0.162000	8.54e-01
REACTOME ENDOGENOUS STEROLS	26	2.48e-01	-0.131000	8.54e-01
REACTOME CD22 MEDIATED BCR REGULATION	5	2.48e-01	-0.298000	8.54e-01
REACTOME RHO GTPASES ACTIVATE WASPS AND WAVES	34	2.49e-01	-0.114000	8.54e-01
REACTOME TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA	17	2.49e-01	0.162000	8.54e-01
REACTOME MEIOTIC SYNAPSIS	73	2.49e-01	0.078100	8.54e-01
REACTOME HSF1 ACTIVATION	29	2.50e-01	0.124000	8.55e-01
REACTOME SIGNALING BY MRAS COMPLEX MUTANTS	7	2.50e-01	-0.251000	8.55e-01
REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	98	2.52e-01	0.067000	8.56e-01
REACTOME ACETYLCHOLINE REGULATES INSULIN SECRETION	10	2.52e-01	-0.209000	8.56e-01
REACTOME COBALAMIN CBL METABOLISM	7	2.53e-01	0.250000	8.56e-01
REACTOME RNA POLYMERASE II TRANSCRIBES SNRNA GENES	77	2.53e-01	0.075400	8.56e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	25	2.53e-01	-0.132000	8.56e-01
REACTOME RHOV GTPASE CYCLE	36	2.54e-01	-0.110000	8.56e-01
REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS	63	2.55e-01	-0.083000	8.56e-01
REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	35	2.55e-01	0.111000	8.56e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES	8	2.56e-01	-0.232000	8.56e-01
REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	10	2.56e-01	-0.207000	8.56e-01
REACTOME EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION	27	2.57e-01	-0.126000	8.56e-01
REACTOME ACYL CHAIN REMODELLING OF PC	27	2.57e-01	0.126000	8.56e-01
REACTOME DNA REPLICATION PRE INITIATION	150	2.57e-01	0.053600	8.56e-01
REACTOME ION CHANNEL TRANSPORT	172	2.58e-01	0.050000	8.57e-01
REACTOME REGULATION OF NPAS4 GENE TRANSCRIPTION	5	2.59e-01	0.291000	8.60e-01
REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	37	2.60e-01	0.107000	8.60e-01
REACTOME NS1 MEDIATED EFFECTS ON HOST PATHWAYS	41	2.60e-01	0.102000	8.60e-01
REACTOME PROPIONYL COA CATABOLISM	5	2.61e-01	0.290000	8.61e-01
REACTOME SURFACTANT METABOLISM	28	2.62e-01	0.123000	8.61e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE GIP	12	2.63e-01	0.187000	8.63e-01
REACTOME G ALPHA 12 13 SIGNALLING EVENTS	74	2.64e-01	-0.075100	8.63e-01
REACTOME PHENYLALANINE METABOLISM	6	2.64e-01	-0.263000	8.63e-01
REACTOME ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS	27	2.65e-01	0.124000	8.63e-01
REACTOME CREB3 FACTORS ACTIVATE GENES	8	2.65e-01	0.228000	8.63e-01
REACTOME SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL	25	2.66e-01	-0.129000	8.63e-01
REACTOME AUTOPHAGY	144	2.67e-01	0.053500	8.68e-01
REACTOME MITOCHONDRIAL PROTEIN IMPORT	58	2.69e-01	0.083900	8.69e-01
REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION	62	2.69e-01	0.081100	8.69e-01
REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES	27	2.69e-01	-0.123000	8.69e-01
REACTOME SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION	8	2.70e-01	0.225000	8.70e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3	11	2.71e-01	-0.192000	8.70e-01
REACTOME GPER1 SIGNALING	45	2.71e-01	-0.094800	8.70e-01
REACTOME NONHOMOLOGOUS END JOINING NHEJ	64	2.72e-01	0.079500	8.70e-01
REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	17	2.73e-01	0.154000	8.71e-01
REACTOME LYSINE CATABOLISM	12	2.73e-01	-0.183000	8.71e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	11	2.75e-01	0.190000	8.75e-01
REACTOME SIGNALING BY ERBB4	57	2.76e-01	-0.083400	8.75e-01
REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	30	2.76e-01	-0.115000	8.75e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS	9	2.78e-01	-0.209000	8.75e-01
REACTOME SIGNALING BY FLT3 ITD AND TKD MUTANTS	16	2.78e-01	-0.157000	8.75e-01
REACTOME CHROMOSOME MAINTENANCE	130	2.78e-01	0.055100	8.75e-01
REACTOME CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY	84	2.78e-01	0.068400	8.75e-01
REACTOME REPRESSION OF WNT TARGET GENES	14	2.79e-01	-0.167000	8.75e-01
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM	688	2.79e-01	0.024200	8.75e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS	5	2.81e-01	-0.278000	8.78e-01
REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	28	2.82e-01	0.118000	8.78e-01
REACTOME RHOB GTPASE CYCLE	67	2.82e-01	-0.076000	8.78e-01
REACTOME ELASTIC FIBRE FORMATION	44	2.82e-01	0.093700	8.78e-01
REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	20	2.83e-01	0.139000	8.79e-01
REACTOME ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA	5	2.85e-01	-0.276000	8.79e-01
REACTOME CELL CYCLE	666	2.85e-01	0.024300	8.79e-01
REACTOME RAS PROCESSING	22	2.85e-01	0.132000	8.79e-01
REACTOME NUCLEOTIDE EXCISION REPAIR	107	2.86e-01	-0.059700	8.80e-01
REACTOME BIOLOGICAL OXIDATIONS	210	2.87e-01	-0.042600	8.80e-01
REACTOME REGULATION OF PTEN GENE TRANSCRIPTION	59	2.87e-01	-0.080100	8.80e-01
REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE	63	2.87e-01	0.077500	8.80e-01
REACTOME MET ACTIVATES RAS SIGNALING	11	2.88e-01	-0.185000	8.80e-01
REACTOME VEGFR2 MEDIATED CELL PROLIFERATION	19	2.88e-01	-0.141000	8.80e-01
REACTOME DNA REPLICATION INITIATION	7	2.92e-01	-0.230000	8.84e-01
REACTOME NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY	6	2.93e-01	-0.248000	8.84e-01
REACTOME DISEASES OF MISMATCH REPAIR MMR	5	2.94e-01	0.271000	8.84e-01
REACTOME INTERLEUKIN 21 SIGNALING	9	2.94e-01	-0.202000	8.84e-01
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	55	2.95e-01	0.081600	8.84e-01
REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ	6	2.95e-01	-0.247000	8.84e-01
REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	16	2.95e-01	0.151000	8.84e-01
REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM	50	2.96e-01	0.085500	8.84e-01
REACTOME GLUCOCORTICOID BIOSYNTHESIS	10	2.96e-01	-0.191000	8.84e-01
REACTOME PEPTIDE LIGAND BINDING RECEPTORS	188	2.96e-01	-0.044200	8.84e-01
REACTOME FREE FATTY ACIDS REGULATE INSULIN SECRETION	10	2.97e-01	-0.191000	8.84e-01
REACTOME TACHYKININ RECEPTORS BIND TACHYKININS	5	2.98e-01	-0.269000	8.84e-01
REACTOME SIGNALING BY FGFR1	49	2.98e-01	-0.085900	8.84e-01
REACTOME SYNTHESIS OF PA	38	2.99e-01	-0.097400	8.84e-01
REACTOME CHL1 INTERACTIONS	9	2.99e-01	0.200000	8.84e-01
REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS	100	2.99e-01	0.060100	8.84e-01
REACTOME POTASSIUM CHANNELS	102	3.00e-01	-0.059400	8.84e-01
REACTOME INDUCTION OF CELL CELL FUSION	12	3.00e-01	0.173000	8.84e-01
REACTOME MITOTIC PROPHASE	134	3.01e-01	0.051800	8.84e-01
REACTOME APOPTOTIC EXECUTION PHASE	49	3.01e-01	-0.085300	8.84e-01
REACTOME ERYTHROPOIETIN ACTIVATES RAS	14	3.02e-01	-0.159000	8.84e-01
REACTOME INACTIVATION OF CDC42 AND RAC1	8	3.02e-01	-0.211000	8.84e-01
REACTOME DSCAM INTERACTIONS	11	3.02e-01	-0.180000	8.84e-01
REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	11	3.03e-01	-0.179000	8.84e-01
REACTOME INTERLEUKIN 17 SIGNALING	66	3.03e-01	0.073300	8.84e-01
REACTOME LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME	11	3.04e-01	-0.179000	8.86e-01
REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	19	3.05e-01	0.136000	8.86e-01
REACTOME GAB1 SIGNALOSOME	17	3.06e-01	-0.143000	8.86e-01
REACTOME RHOU GTPASE CYCLE	37	3.07e-01	-0.097100	8.86e-01
REACTOME EARLY SARS COV 2 INFECTION EVENTS	34	3.07e-01	0.101000	8.86e-01
REACTOME ATTENUATION PHASE	27	3.07e-01	0.114000	8.86e-01
REACTOME INTERLEUKIN 7 SIGNALING	31	3.08e-01	-0.106000	8.86e-01
REACTOME CELLULAR HEXOSE TRANSPORT	21	3.09e-01	0.128000	8.86e-01
REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	11	3.10e-01	-0.177000	8.86e-01
REACTOME SOS MEDIATED SIGNALLING	7	3.10e-01	-0.221000	8.86e-01
REACTOME INOSITOL PHOSPHATE METABOLISM	45	3.11e-01	-0.087300	8.86e-01
REACTOME FRUCTOSE METABOLISM	7	3.11e-01	0.221000	8.86e-01
REACTOME GLYCOGEN METABOLISM	22	3.11e-01	-0.125000	8.86e-01
REACTOME RHOBTB1 GTPASE CYCLE	22	3.12e-01	0.125000	8.87e-01
REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND	21	3.12e-01	0.127000	8.87e-01
REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER	18	3.14e-01	-0.137000	8.87e-01
REACTOME MRNA SPLICING	197	3.14e-01	0.041600	8.87e-01
REACTOME PINK1 PRKN MEDIATED MITOPHAGY	22	3.14e-01	0.124000	8.87e-01
REACTOME AMINO ACIDS REGULATE MTORC1	53	3.15e-01	0.079800	8.87e-01
REACTOME PYRUVATE METABOLISM	29	3.15e-01	0.108000	8.87e-01
REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF	17	3.17e-01	-0.140000	8.88e-01
REACTOME INTERLEUKIN 10 SIGNALING	43	3.17e-01	0.088100	8.88e-01
REACTOME MAPK6 MAPK4 SIGNALING	91	3.18e-01	-0.060500	8.88e-01
REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER	81	3.19e-01	-0.064000	8.88e-01
REACTOME ALK MUTANTS BIND TKIS	12	3.19e-01	-0.166000	8.88e-01
REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	13	3.20e-01	0.159000	8.88e-01
REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	26	3.20e-01	0.113000	8.88e-01
REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	19	3.20e-01	-0.132000	8.88e-01
REACTOME ADHERENS JUNCTIONS INTERACTIONS	33	3.21e-01	0.099900	8.88e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER	28	3.22e-01	0.108000	8.88e-01
REACTOME SUMOYLATION OF DNA METHYLATION PROTEINS	16	3.23e-01	-0.143000	8.88e-01
REACTOME CLEC7A DECTIN 1 SIGNALING	97	3.23e-01	-0.058000	8.88e-01
REACTOME ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS	87	3.23e-01	-0.061200	8.88e-01
REACTOME NEUREXINS AND NEUROLIGINS	51	3.24e-01	-0.079800	8.88e-01
REACTOME ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS	24	3.24e-01	-0.116000	8.88e-01
REACTOME METABOLISM OF POLYAMINES	56	3.25e-01	0.076100	8.88e-01
REACTOME ABC TRANSPORTER DISORDERS	76	3.25e-01	0.065300	8.88e-01
REACTOME PI METABOLISM	79	3.25e-01	-0.064000	8.88e-01
REACTOME MITOTIC SPINDLE CHECKPOINT	109	3.26e-01	0.054500	8.88e-01
REACTOME LAGGING STRAND SYNTHESIS	19	3.26e-01	-0.130000	8.88e-01
REACTOME INLA MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS	9	3.27e-01	0.189000	8.89e-01
REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	19	3.28e-01	0.130000	8.89e-01
REACTOME RET SIGNALING	40	3.29e-01	-0.089200	8.89e-01
REACTOME SIGNALLING TO ERKS	34	3.29e-01	-0.096700	8.89e-01
REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	22	3.30e-01	-0.120000	8.89e-01
REACTOME DUAL INCISION IN TC NER	63	3.30e-01	-0.070900	8.89e-01
REACTOME SERINE BIOSYNTHESIS	9	3.30e-01	0.187000	8.89e-01
REACTOME SUMOYLATION OF DNA REPLICATION PROTEINS	46	3.31e-01	0.082900	8.89e-01
REACTOME TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7	12	3.32e-01	0.162000	8.89e-01
REACTOME PROLONGED ERK ACTIVATION EVENTS	14	3.32e-01	-0.150000	8.89e-01
REACTOME HEME BIOSYNTHESIS	13	3.33e-01	0.155000	8.89e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN	21	3.33e-01	0.122000	8.89e-01
REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV 1 INFECTION	5	3.33e-01	0.250000	8.89e-01
REACTOME MELANIN BIOSYNTHESIS	5	3.36e-01	-0.249000	8.92e-01
REACTOME CYTOSOLIC TRNA AMINOACYLATION	22	3.36e-01	0.118000	8.92e-01
REACTOME PROTEIN REPAIR	6	3.36e-01	0.227000	8.92e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS	8	3.39e-01	0.195000	8.99e-01
REACTOME SYNTHESIS OF 12 EICOSATETRAENOIC ACID DERIVATIVES	7	3.40e-01	-0.208000	8.99e-01
REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS	5	3.41e-01	0.246000	8.99e-01
REACTOME BETA OXIDATION OF BUTANOYL COA TO ACETYL COA	5	3.42e-01	0.246000	8.99e-01
REACTOME LTC4 CYSLTR MEDIATED IL4 PRODUCTION	6	3.42e-01	0.224000	8.99e-01
REACTOME KSRP KHSRP BINDS AND DESTABILIZES MRNA	17	3.47e-01	0.132000	9.09e-01
REACTOME METABOLISM OF PORPHYRINS	26	3.48e-01	0.106000	9.09e-01
REACTOME GAP JUNCTION TRAFFICKING AND REGULATION	49	3.49e-01	-0.077300	9.09e-01
REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE	9	3.49e-01	-0.180000	9.09e-01
REACTOME SPHINGOLIPID METABOLISM	84	3.50e-01	-0.059000	9.09e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	27	3.50e-01	0.104000	9.09e-01
REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK	17	3.50e-01	0.131000	9.09e-01
REACTOME G ALPHA Z SIGNALLING EVENTS	48	3.50e-01	-0.077900	9.09e-01
REACTOME MET INTERACTS WITH TNS PROTEINS	5	3.51e-01	0.241000	9.09e-01
REACTOME CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY	12	3.51e-01	0.156000	9.09e-01
REACTOME MYOCLONIC EPILEPSY OF LAFORA	9	3.54e-01	0.178000	9.15e-01
REACTOME PROTEIN LOCALIZATION	153	3.54e-01	0.043400	9.15e-01
REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS	83	3.55e-01	-0.058700	9.15e-01
REACTOME TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA	36	3.56e-01	0.089000	9.15e-01
REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	11	3.56e-01	0.161000	9.15e-01
REACTOME POLO LIKE KINASE MEDIATED EVENTS	16	3.57e-01	0.133000	9.15e-01
REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	16	3.58e-01	0.133000	9.15e-01
REACTOME G2 M DNA DAMAGE CHECKPOINT	90	3.58e-01	0.056100	9.15e-01
REACTOME DNA REPLICATION	178	3.59e-01	0.039900	9.16e-01
REACTOME BICARBONATE TRANSPORTERS	10	3.61e-01	0.167000	9.16e-01
REACTOME ERKS ARE INACTIVATED	13	3.61e-01	0.146000	9.16e-01
REACTOME GDP FUCOSE BIOSYNTHESIS	6	3.61e-01	-0.215000	9.16e-01
REACTOME MTOR SIGNALLING	40	3.61e-01	0.083500	9.16e-01
REACTOME TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER	76	3.62e-01	-0.060500	9.16e-01
REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS	21	3.64e-01	-0.115000	9.20e-01
REACTOME TIE2 SIGNALING	18	3.65e-01	-0.123000	9.20e-01
REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE	11	3.65e-01	-0.158000	9.20e-01
REACTOME SYNTHESIS OF PG	8	3.66e-01	-0.185000	9.20e-01
REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS	17	3.68e-01	-0.126000	9.20e-01
REACTOME PHASE 1 INACTIVATION OF FAST NA CHANNELS	6	3.69e-01	0.212000	9.20e-01
REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS	6	3.69e-01	-0.212000	9.20e-01
REACTOME TRANSPORT OF NUCLEOTIDE SUGARS	8	3.70e-01	-0.183000	9.20e-01
REACTOME GAP JUNCTION ASSEMBLY	36	3.70e-01	-0.086300	9.20e-01
REACTOME RNA POLYMERASE III CHAIN ELONGATION	18	3.71e-01	0.122000	9.20e-01
REACTOME DEVELOPMENTAL BIOLOGY	1115	3.71e-01	0.015900	9.20e-01
REACTOME POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION	27	3.71e-01	0.099400	9.20e-01
REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX	9	3.73e-01	0.172000	9.20e-01
REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION	8	3.73e-01	0.182000	9.20e-01
REACTOME EGFR INTERACTS WITH PHOSPHOLIPASE C GAMMA	9	3.74e-01	0.171000	9.20e-01
REACTOME ENOS ACTIVATION	11	3.74e-01	-0.155000	9.20e-01
REACTOME REGULATED NECROSIS	57	3.74e-01	0.068000	9.20e-01
REACTOME RHOC GTPASE CYCLE	71	3.74e-01	-0.061000	9.20e-01
REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL	12	3.75e-01	0.148000	9.20e-01
REACTOME THE NLRP3 INFLAMMASOME	16	3.75e-01	-0.128000	9.20e-01
REACTOME SULFIDE OXIDATION TO SULFATE	6	3.76e-01	-0.209000	9.20e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2	13	3.76e-01	-0.142000	9.20e-01
REACTOME LATE SARS COV 2 INFECTION EVENTS	67	3.77e-01	0.062500	9.20e-01
REACTOME EPHA MEDIATED GROWTH CONE COLLAPSE	29	3.79e-01	0.094400	9.20e-01
REACTOME COLLAGEN DEGRADATION	61	3.80e-01	0.065100	9.20e-01
REACTOME INTERLEUKIN 27 SIGNALING	11	3.80e-01	-0.153000	9.20e-01
REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	22	3.81e-01	-0.108000	9.20e-01
REACTOME REGULATION OF IFNA IFNB SIGNALING	23	3.82e-01	-0.105000	9.20e-01
REACTOME DOPAMINE RECEPTORS	5	3.83e-01	-0.225000	9.20e-01
REACTOME SNRNP ASSEMBLY	53	3.84e-01	0.069100	9.20e-01
REACTOME UB SPECIFIC PROCESSING PROTEASES	187	3.84e-01	0.036900	9.20e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	24	3.86e-01	-0.102000	9.20e-01
REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	28	3.86e-01	0.094600	9.20e-01
REACTOME SUMOYLATION OF UBIQUITINYLATION PROTEINS	39	3.87e-01	0.080100	9.20e-01
REACTOME LYSOSOME VESICLE BIOGENESIS	33	3.87e-01	-0.087100	9.20e-01
REACTOME REGULATION OF NPAS4 GENE EXPRESSION	13	3.88e-01	-0.138000	9.20e-01
REACTOME SYNTHESIS OF DOLICHYL PHOSPHATE	6	3.88e-01	0.204000	9.20e-01
REACTOME TCR SIGNALING	113	3.88e-01	-0.047000	9.20e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS	7	3.88e-01	0.188000	9.20e-01
REACTOME MUSCLE CONTRACTION	197	3.88e-01	0.035700	9.20e-01
REACTOME UCH PROTEINASES	99	3.88e-01	0.050200	9.20e-01
REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS	6	3.89e-01	-0.203000	9.20e-01
REACTOME SIGNALING BY BMP	27	3.90e-01	-0.095600	9.20e-01
REACTOME STAT5 ACTIVATION	7	3.90e-01	-0.188000	9.20e-01
REACTOME CAMK IV MEDIATED PHOSPHORYLATION OF CREB	10	3.91e-01	0.157000	9.20e-01
REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	20	3.91e-01	0.111000	9.20e-01
REACTOME ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES	59	3.92e-01	0.064500	9.20e-01
REACTOME SYNTHESIS OF GDP MANNOSE	5	3.92e-01	0.221000	9.20e-01
REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	13	3.93e-01	0.137000	9.20e-01
REACTOME CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2	11	3.93e-01	-0.149000	9.20e-01
REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	14	3.94e-01	-0.132000	9.20e-01
REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION	42	3.94e-01	-0.076000	9.20e-01
REACTOME NOSTRIN MEDIATED ENOS TRAFFICKING	5	3.95e-01	-0.220000	9.20e-01
REACTOME KETONE BODY METABOLISM	9	3.95e-01	-0.164000	9.20e-01
REACTOME INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL	14	3.96e-01	0.131000	9.20e-01
REACTOME ATTACHMENT OF GPI ANCHOR TO UPAR	7	3.96e-01	0.185000	9.20e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX2	117	3.96e-01	-0.045400	9.20e-01
REACTOME RIPK1 MEDIATED REGULATED NECROSIS	30	3.96e-01	0.089500	9.20e-01
REACTOME FORMATION OF PARAXIAL MESODERM	22	3.98e-01	-0.104000	9.20e-01
REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET	8	3.98e-01	-0.173000	9.20e-01
REACTOME DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS	19	3.98e-01	0.112000	9.20e-01
REACTOME SMALL INTERFERING RNA SIRNA BIOGENESIS	9	3.98e-01	-0.163000	9.20e-01
REACTOME DNA DOUBLE STRAND BREAK REPAIR	162	3.99e-01	0.038400	9.20e-01
REACTOME DISEASES OF IMMUNE SYSTEM	29	3.99e-01	-0.090500	9.20e-01
REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	13	4.00e-01	-0.135000	9.20e-01
REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	15	4.00e-01	-0.126000	9.20e-01
REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS	55	4.02e-01	0.065300	9.23e-01
REACTOME E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS	58	4.04e-01	0.063300	9.23e-01
REACTOME MRNA CAPPING	28	4.05e-01	-0.090900	9.23e-01
REACTOME INTERLEUKIN 2 FAMILY SIGNALING	40	4.05e-01	-0.076100	9.23e-01
REACTOME INTERLEUKIN 18 SIGNALING	8	4.06e-01	0.170000	9.23e-01
REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	67	4.06e-01	-0.058700	9.23e-01
REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	20	4.08e-01	-0.107000	9.23e-01
REACTOME TRANSCRIPTIONAL REGULATION BY E2F6	32	4.08e-01	-0.084500	9.23e-01
REACTOME REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE	81	4.09e-01	0.053100	9.23e-01
REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	48	4.09e-01	-0.068900	9.23e-01
REACTOME PTEN REGULATION	135	4.10e-01	-0.041000	9.23e-01
REACTOME SIGNALLING TO P38 VIA RIT AND RIN	5	4.11e-01	-0.212000	9.23e-01
REACTOME SUMO IS TRANSFERRED FROM E1 TO E2 UBE2I UBC9	7	4.11e-01	-0.180000	9.23e-01
REACTOME AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA	54	4.11e-01	0.064700	9.23e-01
REACTOME PROTON COUPLED MONOCARBOXYLATE TRANSPORT	6	4.11e-01	-0.194000	9.23e-01
REACTOME G1 S SPECIFIC TRANSCRIPTION	28	4.11e-01	0.089800	9.23e-01
REACTOME SIGNALING BY FGFR	85	4.12e-01	-0.051500	9.23e-01
REACTOME MHC CLASS II ANTIGEN PRESENTATION	121	4.12e-01	-0.043100	9.23e-01
REACTOME TRIGLYCERIDE BIOSYNTHESIS	12	4.13e-01	-0.137000	9.23e-01
REACTOME ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS	41	4.13e-01	-0.073900	9.23e-01
REACTOME PHOSPHOLIPID METABOLISM	201	4.14e-01	-0.033400	9.23e-01
REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	51	4.15e-01	-0.066000	9.23e-01
REACTOME INWARDLY RECTIFYING K CHANNELS	35	4.15e-01	-0.079600	9.23e-01
REACTOMEMATURATION OF SARS COV 1 NUCLEOPROTEIN	11	4.15e-01	-0.142000	9.23e-01
REACTOME LIPID PARTICLE ORGANIZATION	6	4.16e-01	0.192000	9.23e-01
REACTOME PURINE SALVAGE	12	4.17e-01	-0.135000	9.23e-01
REACTOME FLT3 SIGNALING THROUGH SRC FAMILY KINASES	6	4.17e-01	-0.191000	9.23e-01
REACTOME DIGESTION OF DIETARY LIPID	7	4.17e-01	0.177000	9.23e-01
REACTOME EGFR TRANSACTIVATION BY GASTRIN	9	4.18e-01	0.156000	9.23e-01
REACTOME IKBA VARIANT LEADS TO EDA ID	6	4.18e-01	-0.191000	9.23e-01
REACTOME L1CAM INTERACTIONS	112	4.19e-01	-0.044200	9.23e-01
REACTOME DNA DAMAGE REVERSAL	8	4.19e-01	-0.165000	9.23e-01
REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	11	4.20e-01	-0.140000	9.24e-01
REACTOME OTHER SEMAPHORIN INTERACTIONS	18	4.21e-01	0.110000	9.24e-01
REACTOME DEPOLYMERISATION OF THE NUCLEAR LAMINA	14	4.22e-01	-0.124000	9.25e-01
REACTOME DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE	76	4.22e-01	0.053200	9.25e-01
REACTOME MITOTIC PROMETAPHASE	194	4.25e-01	0.033200	9.26e-01
REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES	77	4.25e-01	-0.052600	9.26e-01
REACTOME SARS COV 1 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS	16	4.26e-01	-0.115000	9.26e-01
REACTOME DISINHIBITION OF SNARE FORMATION	5	4.26e-01	-0.205000	9.26e-01
REACTOME TRAIL SIGNALING	8	4.27e-01	0.162000	9.26e-01
REACTOME ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM	12	4.29e-01	0.132000	9.26e-01
REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	76	4.29e-01	0.052500	9.26e-01
REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	13	4.29e-01	-0.127000	9.26e-01
REACTOME PP2A MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS	6	4.29e-01	0.186000	9.26e-01
REACTOME CYCLIN D ASSOCIATED EVENTS IN G1	46	4.29e-01	-0.067400	9.26e-01
REACTOME METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES	33	4.30e-01	-0.079400	9.26e-01
REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	35	4.30e-01	-0.077100	9.26e-01
REACTOME FATTY ACIDS BOUND TO GPR40 FFAR1 REGULATE INSULIN SECRETION	8	4.30e-01	-0.161000	9.26e-01
REACTOME RHO GTPASES ACTIVATE KTN1	11	4.31e-01	-0.137000	9.26e-01
REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS	312	4.32e-01	-0.025900	9.27e-01
REACTOME PTK6 EXPRESSION	5	4.34e-01	-0.202000	9.31e-01
REACTOME MASTL FACILITATES MITOTIC PROGRESSION	10	4.36e-01	0.142000	9.31e-01
REACTOME INTEGRATION OF ENERGY METABOLISM	105	4.36e-01	-0.044000	9.31e-01
REACTOME INITIAL TRIGGERING OF COMPLEMENT	21	4.37e-01	0.098000	9.31e-01
REACTOME LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS	19	4.37e-01	0.103000	9.31e-01
REACTOME FATTY ACID METABOLISM	170	4.39e-01	-0.034400	9.31e-01
REACTOME DEFECTIVE RIPK1 MEDIATED REGULATED NECROSIS	7	4.39e-01	-0.169000	9.31e-01
REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES	18	4.40e-01	0.105000	9.31e-01
REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	26	4.41e-01	0.087300	9.31e-01
REACTOME TRANSPORT OF FATTY ACIDS	8	4.42e-01	0.157000	9.31e-01
REACTOME P2Y RECEPTORS	9	4.43e-01	0.148000	9.31e-01
REACTOME PKA ACTIVATION IN GLUCAGON SIGNALLING	17	4.43e-01	-0.107000	9.31e-01
REACTOME STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES	16	4.43e-01	0.111000	9.31e-01
REACTOME DEFENSINS	33	4.45e-01	0.076800	9.31e-01
REACTOME MRNA SPLICING MINOR PATHWAY	49	4.46e-01	0.063000	9.31e-01
REACTOME SYNTHESIS OF 5 EICOSATETRAENOIC ACIDS	9	4.46e-01	-0.147000	9.31e-01
REACTOME MISCELLANEOUS TRANSPORT AND BINDING EVENTS	24	4.47e-01	-0.089700	9.31e-01
REACTOME PIWI INTERACTING RNA PIRNA BIOGENESIS	29	4.47e-01	-0.081500	9.31e-01
REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	23	4.48e-01	-0.091500	9.31e-01
REACTOME NICOTINATE METABOLISM	31	4.48e-01	-0.078800	9.31e-01
REACTOME ARACHIDONIC ACID METABOLISM	57	4.48e-01	-0.058100	9.31e-01
REACTOME DECTIN 2 FAMILY	26	4.48e-01	0.085900	9.31e-01
REACTOME INTERLEUKIN 1 FAMILY SIGNALING	146	4.49e-01	-0.036300	9.31e-01
REACTOME HOMOLOGY DIRECTED REPAIR	132	4.50e-01	0.038100	9.31e-01
REACTOME TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX	14	4.51e-01	0.116000	9.31e-01
REACTOME PD 1 SIGNALING	21	4.52e-01	-0.094900	9.31e-01
REACTOME BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA	5	4.53e-01	0.194000	9.31e-01
REACTOME VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS	42	4.53e-01	-0.066900	9.31e-01
REACTOME LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX	5	4.53e-01	-0.194000	9.31e-01
REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	9	4.54e-01	-0.144000	9.31e-01
REACTOME NETRIN MEDIATED REPULSION SIGNALS	8	4.54e-01	0.153000	9.31e-01
REACTOME ALPHA DEFENSINS	6	4.54e-01	0.176000	9.31e-01
REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY	25	4.54e-01	-0.086500	9.31e-01
REACTOME RELEASE OF HH NP FROM THE SECRETING CELL	8	4.56e-01	-0.152000	9.31e-01
REACTOME LDL REMODELING	6	4.56e-01	0.176000	9.31e-01
REACTOME SYNTHESIS OF KETONE BODIES	8	4.56e-01	-0.152000	9.31e-01
REACTOME BASE EXCISION REPAIR	87	4.56e-01	0.046200	9.31e-01
REACTOME RESOLUTION OF ABASIC SITES AP SITES	38	4.56e-01	-0.069800	9.31e-01
REACTOME SIGNALING BY ALK	26	4.56e-01	-0.084400	9.31e-01
REACTOME ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING	9	4.57e-01	-0.143000	9.31e-01
REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	86	4.57e-01	0.046400	9.31e-01
REACTOME BIOTIN TRANSPORT AND METABOLISM	10	4.59e-01	0.135000	9.33e-01
REACTOME INTERLEUKIN 1 SIGNALING	110	4.59e-01	-0.040800	9.33e-01
REACTOME EICOSANOIDS	12	4.60e-01	0.123000	9.33e-01
REACTOME COPII MEDIATED VESICLE TRANSPORT	66	4.61e-01	-0.052500	9.33e-01
REACTOME GLYCOSPHINGOLIPID METABOLISM	39	4.61e-01	-0.068200	9.33e-01
REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX	39	4.62e-01	-0.068100	9.33e-01
REACTOME METABOLISM OF LIPIDS	709	4.62e-01	-0.016200	9.33e-01
REACTOME RHOJ GTPASE CYCLE	51	4.64e-01	-0.059200	9.34e-01
REACTOME TBC RABGAPS	40	4.65e-01	-0.066700	9.34e-01
REACTOME CYTOPROTECTION BY HMOX1	59	4.65e-01	-0.054900	9.34e-01
REACTOME RHO GTPASE EFFECTORS	305	4.66e-01	-0.024300	9.34e-01
REACTOME RECYCLING OF BILE ACIDS AND SALTS	18	4.68e-01	0.098800	9.34e-01
REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	57	4.68e-01	-0.055500	9.34e-01
REACTOME ACTIVATION OF AMPK DOWNSTREAM OF NMDARS	28	4.69e-01	-0.079100	9.34e-01
REACTOME VITAMIN C ASCORBATE METABOLISM	8	4.69e-01	-0.148000	9.34e-01
REACTOME TRANSPORT AND SYNTHESIS OF PAPS	6	4.70e-01	-0.171000	9.34e-01
REACTOME ACTIVATION OF PPARGC1A PGC 1ALPHA BY PHOSPHORYLATION	10	4.70e-01	0.132000	9.34e-01
REACTOME NEDDYLATION	235	4.70e-01	-0.027300	9.34e-01
REACTOME INNATE IMMUNE SYSTEM	1002	4.71e-01	-0.013500	9.34e-01
REACTOME DOWNREGULATION OF ERBB2 SIGNALING	29	4.73e-01	0.077000	9.34e-01
REACTOME HISTIDINE CATABOLISM	8	4.73e-01	0.147000	9.34e-01
REACTOME PHOSPHORYLATION OF THE APC C	20	4.73e-01	-0.092600	9.34e-01
REACTOME INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS	37	4.73e-01	0.068100	9.34e-01
REACTOME DISEASES ASSOCIATED WITH SURFACTANT METABOLISM	9	4.73e-01	0.138000	9.34e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS	5	4.74e-01	-0.185000	9.34e-01
REACTOME GABA B RECEPTOR ACTIVATION	43	4.74e-01	-0.063100	9.34e-01
REACTOME HIV TRANSCRIPTION ELONGATION	42	4.74e-01	-0.063800	9.34e-01
REACTOME IRE1ALPHA ACTIVATES CHAPERONES	48	4.74e-01	0.059700	9.34e-01
REACTOME REGULATION OF PTEN STABILITY AND ACTIVITY	67	4.75e-01	0.050400	9.34e-01
REACTOME RHOBTB3 ATPASE CYCLE	8	4.76e-01	-0.146000	9.34e-01
REACTOME IRAK1 RECRUITS IKK COMPLEX	12	4.77e-01	0.119000	9.34e-01
REACTOME CREB PHOSPHORYLATION	6	4.78e-01	0.167000	9.34e-01
REACTOME FORMATION OF INCISION COMPLEX IN GG NER	40	4.78e-01	-0.064800	9.34e-01
REACTOME TLR3 MEDIATED TICAM1 DEPENDENT PROGRAMMED CELL DEATH	6	4.79e-01	-0.167000	9.34e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX	19	4.80e-01	0.093700	9.34e-01
REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS	33	4.80e-01	0.071100	9.34e-01
REACTOME INTERFERON GAMMA SIGNALING	88	4.80e-01	0.043500	9.34e-01
REACTOME SENSING OF DNA DOUBLE STRAND BREAKS	6	4.83e-01	0.166000	9.34e-01
REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE	277	4.84e-01	0.024400	9.34e-01
REACTOME WNT MEDIATED ACTIVATION OF DVL	8	4.85e-01	-0.143000	9.34e-01
REACTOME NFE2L2 REGULATING ANTI OXIDANT DETOXIFICATION ENZYMES	17	4.85e-01	0.097900	9.34e-01
REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING	25	4.85e-01	0.080700	9.34e-01
REACTOME SIGNALING BY MAPK MUTANTS	6	4.85e-01	-0.165000	9.34e-01
REACTOME TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS	43	4.85e-01	0.061500	9.34e-01
REACTOME KERATAN SULFATE BIOSYNTHESIS	28	4.86e-01	-0.076000	9.34e-01
REACTOME MITOCHONDRIAL CALCIUM ION TRANSPORT	23	4.87e-01	0.083700	9.34e-01
REACTOME SARS COV 2 MODULATES AUTOPHAGY	11	4.88e-01	-0.121000	9.34e-01
REACTOME MEMBRANE TRAFFICKING	603	4.88e-01	-0.016500	9.34e-01
REACTOME PREDNISONE ADME	10	4.89e-01	-0.126000	9.34e-01
REACTOME MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS	13	4.89e-01	0.111000	9.34e-01
REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	14	4.89e-01	0.107000	9.34e-01
REACTOME RND2 GTPASE CYCLE	42	4.89e-01	-0.061700	9.34e-01
REACTOME MITOPHAGY	28	4.89e-01	0.075500	9.34e-01
REACTOME SIGNALING BY HEDGEHOG	148	4.90e-01	-0.032900	9.34e-01
REACTOME RNA POLYMERASE I PROMOTER ESCAPE	83	4.90e-01	0.043800	9.34e-01
REACTOME ERBB2 REGULATES CELL MOTILITY	15	4.91e-01	0.103000	9.34e-01
REACTOME ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS	20	4.92e-01	-0.088700	9.34e-01
REACTOME VXPX CARGO TARGETING TO CILIUM	20	4.93e-01	0.088600	9.34e-01
REACTOME SIGNALING BY PDGF	57	4.93e-01	-0.052500	9.34e-01
REACTOME DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS	25	4.93e-01	0.079200	9.34e-01
REACTOME PHASE 2 PLATEAU PHASE	14	4.94e-01	0.106000	9.34e-01
REACTOME KERATAN SULFATE DEGRADATION	13	4.94e-01	0.110000	9.34e-01
REACTOME POTENTIAL THERAPEUTICS FOR SARS	92	4.95e-01	-0.041200	9.34e-01
REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	16	4.95e-01	-0.098500	9.34e-01
REACTOME ASPIRIN ADME	42	4.96e-01	-0.060800	9.34e-01
REACTOME VIRAL MESSENGER RNA SYNTHESIS	44	4.97e-01	0.059200	9.35e-01
REACTOME GENE SILENCING BY RNA	133	4.97e-01	0.034100	9.35e-01
REACTOME TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS	29	4.98e-01	-0.072700	9.35e-01
REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	19	4.99e-01	0.089600	9.35e-01
REACTOME SIGNALING BY INTERLEUKINS	444	5.00e-01	0.018700	9.35e-01
REACTOME ORC1 REMOVAL FROM CHROMATIN	70	5.02e-01	0.046400	9.35e-01
REACTOME CD209 DC SIGN SIGNALING	20	5.02e-01	-0.086700	9.35e-01
REACTOME LYSOSPHINGOLIPID AND LPA RECEPTORS	14	5.02e-01	-0.104000	9.35e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA	27	5.02e-01	-0.074600	9.35e-01
REACTOME POLYMERASE SWITCHING	13	5.02e-01	-0.107000	9.35e-01
REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	99	5.03e-01	0.039000	9.35e-01
REACTOME GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION	7	5.03e-01	0.146000	9.35e-01
REACTOME SIGNALING BY NOTCH2	32	5.03e-01	0.068400	9.35e-01
REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	30	5.05e-01	0.070300	9.36e-01
REACTOME NEUROFASCIN INTERACTIONS	6	5.05e-01	-0.157000	9.36e-01
REACTOME FLT3 SIGNALING BY CBL MUTANTS	7	5.06e-01	0.145000	9.36e-01
REACTOME REGULATED PROTEOLYSIS OF P75NTR	11	5.07e-01	-0.116000	9.36e-01
REACTOME TRANSLESION SYNTHESIS BY POLH	19	5.07e-01	0.088000	9.36e-01
REACTOME REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS	11	5.07e-01	-0.115000	9.36e-01
REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA	28	5.08e-01	0.072200	9.37e-01
REACTOME HDMS DEMETHYLATE HISTONES	40	5.09e-01	0.060300	9.37e-01
REACTOME RMTS METHYLATE HISTONE ARGININES	72	5.10e-01	0.044900	9.37e-01
REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL	13	5.11e-01	-0.105000	9.37e-01
REACTOME PTK6 REGULATES CELL CYCLE	6	5.11e-01	-0.155000	9.37e-01
REACTOME TRYPTOPHAN CATABOLISM	14	5.12e-01	-0.101000	9.37e-01
REACTOME SIGNALING BY NTRKS	132	5.12e-01	-0.033000	9.37e-01
REACTOME DISEASES OF CARBOHYDRATE METABOLISM	31	5.12e-01	0.068000	9.37e-01
REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION	98	5.14e-01	0.038100	9.37e-01
REACTOME NICOTINAMIDE SALVAGING	19	5.15e-01	-0.086200	9.37e-01
REACTOME RESOLUTION OF SISTER CHROMATID COHESION	120	5.16e-01	0.034400	9.37e-01
REACTOME METABOLISM OF NUCLEOTIDES	94	5.16e-01	-0.038800	9.37e-01
REACTOME BETA CATENIN PHOSPHORYLATION CASCADE	16	5.16e-01	-0.093800	9.37e-01
REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES	39	5.16e-01	0.060100	9.37e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE	5	5.18e-01	-0.167000	9.37e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION TERMINATION	30	5.18e-01	-0.068200	9.37e-01
REACTOME TRANSCRIPTIONAL REGULATION BY VENTX	41	5.19e-01	-0.058200	9.37e-01
REACTOME FGFR2B LIGAND BINDING AND ACTIVATION	10	5.20e-01	0.118000	9.37e-01
REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES	29	5.22e-01	0.068800	9.37e-01
REACTOME GLUCURONIDATION	23	5.22e-01	-0.077100	9.37e-01
REACTOME CONJUGATION OF BENZOATE WITH GLYCINE	6	5.22e-01	-0.151000	9.37e-01
REACTOME CGMP EFFECTS	16	5.23e-01	0.092200	9.37e-01
REACTOME MET RECEPTOR ACTIVATION	6	5.23e-01	0.150000	9.37e-01
REACTOME ACTIVATION OF MATRIX METALLOPROTEINASES	30	5.24e-01	0.067300	9.37e-01
REACTOME SYNTHESIS OF 15 EICOSATETRAENOIC ACID DERIVATIVES	6	5.24e-01	-0.150000	9.37e-01
REACTOME HS GAG DEGRADATION	19	5.24e-01	0.084300	9.37e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST	14	5.25e-01	-0.098000	9.37e-01
REACTOME PROCESSING AND ACTIVATION OF SUMO	10	5.26e-01	-0.116000	9.37e-01
REACTOME SIGNALING BY VEGF	102	5.28e-01	-0.036200	9.37e-01
REACTOME PLATELET SENSITIZATION BY LDL	17	5.28e-01	-0.088400	9.37e-01
REACTOME SYNTHESIS OF PIPS AT THE ER MEMBRANE	5	5.29e-01	0.163000	9.37e-01
REACTOME REGULATION OF RUNX3 EXPRESSION AND ACTIVITY	54	5.29e-01	0.049600	9.37e-01
REACTOME STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS	10	5.29e-01	-0.115000	9.37e-01
REACTOME MITOTIC METAPHASE AND ANAPHASE	228	5.29e-01	0.024200	9.37e-01
REACTOME PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR	21	5.29e-01	-0.079400	9.37e-01
REACTOME C TYPE LECTIN RECEPTORS CLRS	136	5.29e-01	-0.031300	9.37e-01
REACTOME ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY	10	5.30e-01	0.115000	9.37e-01
REACTOME ERK MAPK TARGETS	20	5.30e-01	0.081100	9.37e-01
REACTOME DEFECTIVE CSF2RB CAUSES SMDP5	7	5.31e-01	0.137000	9.37e-01
REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES	14	5.31e-01	-0.096700	9.37e-01
REACTOME INSULIN RECEPTOR RECYCLING	29	5.32e-01	-0.067000	9.37e-01
REACTOME DNA METHYLATION	58	5.32e-01	0.047400	9.37e-01
REACTOME DUAL INCISION IN GG NER	39	5.33e-01	-0.057800	9.37e-01
REACTOME SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL	8	5.35e-01	0.127000	9.40e-01
REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS	60	5.35e-01	0.046300	9.40e-01
REACTOME STABILIZATION OF P53	56	5.36e-01	0.047800	9.41e-01
REACTOME EARLY PHASE OF HIV LIFE CYCLE	14	5.37e-01	0.095400	9.41e-01
REACTOME DEFECTS IN BIOTIN BTN METABOLISM	8	5.37e-01	0.126000	9.41e-01
REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION	90	5.38e-01	-0.037500	9.41e-01
REACTOME TIGHT JUNCTION INTERACTIONS	29	5.40e-01	-0.065800	9.42e-01
REACTOME EPITHELIAL MESENCHYMAL TRANSITION EMT DURING GASTRULATION	7	5.40e-01	-0.134000	9.42e-01
REACTOME NUCLEAR IMPORT OF REV PROTEIN	34	5.42e-01	0.060500	9.43e-01
REACTOME NUCLEOTIDE BIOSYNTHESIS	14	5.42e-01	0.094200	9.43e-01
REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	11	5.42e-01	0.106000	9.43e-01
REACTOME RND3 GTPASE CYCLE	41	5.44e-01	0.054700	9.44e-01
REACTOME CHROMATIN MODIFYING ENZYMES	252	5.44e-01	-0.022200	9.44e-01
REACTOME CREATINE METABOLISM	9	5.45e-01	-0.117000	9.44e-01
REACTOME ATTACHMENT AND ENTRY	16	5.45e-01	0.087400	9.44e-01
REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	26	5.47e-01	0.068200	9.46e-01
REACTOME SYNTHESIS OF PI	5	5.48e-01	0.155000	9.47e-01
REACTOME REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION	84	5.49e-01	0.037800	9.47e-01
REACTOME RORA ACTIVATES GENE EXPRESSION	17	5.49e-01	-0.083900	9.47e-01
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	122	5.50e-01	-0.031400	9.47e-01
REACTOME INTERLEUKIN 37 SIGNALING	20	5.50e-01	-0.077100	9.47e-01
REACTOME P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1	6	5.51e-01	0.141000	9.47e-01
REACTOME MET ACTIVATES PTPN11	5	5.51e-01	0.154000	9.47e-01
REACTOME EPHB MEDIATED FORWARD SIGNALING	41	5.53e-01	-0.053500	9.47e-01
REACTOME TERMINAL PATHWAY OF COMPLEMENT	8	5.53e-01	0.121000	9.47e-01
REACTOME SIGNAL ATTENUATION	10	5.54e-01	-0.108000	9.47e-01
REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	45	5.55e-01	-0.050900	9.47e-01
REACTOME SULFUR AMINO ACID METABOLISM	27	5.55e-01	0.065600	9.47e-01
REACTOME GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION	14	5.56e-01	-0.090900	9.47e-01
REACTOME TRANSLESION SYNTHESIS BY POLK	17	5.57e-01	-0.082400	9.47e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES	33	5.57e-01	-0.059100	9.47e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING	6	5.57e-01	-0.139000	9.47e-01
REACTOME SUMOYLATION OF SUMOYLATION PROTEINS	35	5.57e-01	0.057300	9.47e-01
REACTOME REGULATION OF INSULIN SECRETION	77	5.59e-01	-0.038600	9.48e-01
REACTOME METALLOTHIONEINS BIND METALS	11	5.59e-01	-0.102000	9.48e-01
REACTOME METABOLISM OF COFACTORS	19	5.61e-01	0.077000	9.49e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS	9	5.61e-01	-0.112000	9.49e-01
REACTOME TELOMERE C STRAND LAGGING STRAND SYNTHESIS	33	5.62e-01	-0.058300	9.49e-01
REACTOME TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT	18	5.63e-01	0.078800	9.49e-01
REACTOME SEPARATION OF SISTER CHROMATIDS	184	5.64e-01	0.024700	9.49e-01
REACTOME NEUROTRANSMITTER CLEARANCE	9	5.64e-01	0.111000	9.49e-01
REACTOME REGULATION OF PTEN LOCALIZATION	8	5.64e-01	0.118000	9.49e-01
REACTOME PHASE 0 RAPID DEPOLARISATION	31	5.64e-01	0.059800	9.49e-01
REACTOME S PHASE	159	5.65e-01	0.026500	9.49e-01
REACTOME BASIGIN INTERACTIONS	24	5.66e-01	-0.067700	9.50e-01
REACTOME ACTIVATION OF TRKA RECEPTORS	6	5.67e-01	-0.135000	9.50e-01
REACTOME HS GAG BIOSYNTHESIS	28	5.67e-01	0.062600	9.50e-01
REACTOME GROWTH HORMONE RECEPTOR SIGNALING	24	5.68e-01	-0.067400	9.50e-01
REACTOME FATTY ACIDS	15	5.68e-01	0.085200	9.50e-01
REACTOME VITAMIN B2 RIBOFLAVIN METABOLISM	7	5.69e-01	-0.124000	9.50e-01
REACTOME COMMON PATHWAY OF FIBRIN CLOT FORMATION	21	5.73e-01	0.071100	9.56e-01
REACTOME MICRORNA MIRNA BIOGENESIS	25	5.74e-01	-0.065000	9.56e-01
REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	54	5.75e-01	0.044100	9.58e-01
REACTOME GLYCEROPHOSPHOLIPID CATABOLISM	7	5.77e-01	-0.122000	9.59e-01
REACTOME HEDGEHOG OFF STATE	111	5.77e-01	-0.030600	9.59e-01
REACTOME HUR ELAVL1 BINDS AND STABILIZES MRNA	8	5.78e-01	-0.114000	9.59e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE	20	5.79e-01	-0.071700	9.59e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FYN	7	5.79e-01	-0.121000	9.59e-01
REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING	6	5.82e-01	-0.130000	9.60e-01
REACTOME HEDGEHOG LIGAND BIOGENESIS	64	5.82e-01	0.039800	9.60e-01
REACTOME EXTENSION OF TELOMERES	49	5.83e-01	-0.045400	9.60e-01
REACTOME UREA CYCLE	9	5.83e-01	-0.106000	9.60e-01
REACTOME HIV INFECTION	223	5.83e-01	0.021300	9.60e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	34	5.84e-01	-0.054300	9.60e-01
REACTOME DRUG MEDIATED INHIBITION OF CDK4 CDK6 ACTIVITY	5	5.84e-01	-0.141000	9.60e-01
REACTOME RIBAVIRIN ADME	11	5.85e-01	-0.095200	9.60e-01
REACTOME ORGANIC CATION TRANSPORT	10	5.85e-01	0.099800	9.60e-01
REACTOME RUNX3 REGULATES CDKN1A TRANSCRIPTION	7	5.86e-01	-0.119000	9.60e-01
REACTOME PLASMA LIPOPROTEIN REMODELING	33	5.86e-01	0.054700	9.60e-01
REACTOME NTRK2 ACTIVATES RAC1	5	5.87e-01	-0.140000	9.60e-01
REACTOME NEF MEDIATED CD4 DOWN REGULATION	9	5.88e-01	-0.104000	9.60e-01
REACTOME ACYL CHAIN REMODELING OF CL	5	5.88e-01	-0.140000	9.60e-01
REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX	32	5.88e-01	-0.055300	9.60e-01
REACTOME TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY	16	5.90e-01	-0.077700	9.63e-01
REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	46	5.93e-01	0.045600	9.65e-01
REACTOME SARS COV 2 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS	12	5.93e-01	-0.089200	9.65e-01
REACTOME UPTAKE OF DIETARY COBALAMINS INTO ENTEROCYTES	9	5.93e-01	-0.103000	9.65e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING	5	5.95e-01	-0.137000	9.66e-01
REACTOME MEIOTIC RECOMBINATION	80	5.96e-01	0.034300	9.66e-01
REACTOME DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA	77	5.96e-01	0.034900	9.66e-01
REACTOME RUNX3 REGULATES WNT SIGNALING	8	5.98e-01	0.108000	9.67e-01
REACTOME MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS	7	5.98e-01	-0.115000	9.67e-01
REACTOME DISEASES OF PROGRAMMED CELL DEATH	96	5.99e-01	0.031100	9.67e-01
REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	22	6.00e-01	0.064600	9.68e-01
REACTOME SIGNALING BY TGFB FAMILY MEMBERS	119	6.01e-01	0.027800	9.69e-01
REACTOME MYD88 INDEPENDENT TLR4 CASCADE	103	6.02e-01	0.029800	9.69e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS	15	6.03e-01	0.077500	9.69e-01
REACTOME SIGNALING BY NOTCH	234	6.03e-01	-0.019700	9.69e-01
REACTOME MET ACTIVATES PI3K AKT SIGNALING	6	6.04e-01	-0.122000	9.69e-01
REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	22	6.05e-01	0.063700	9.69e-01
REACTOME METABOLISM OF FAT SOLUBLE VITAMINS	46	6.05e-01	0.044000	9.69e-01
REACTOME ADRENOCEPTORS	9	6.06e-01	-0.099300	9.69e-01
REACTOME DOWNREGULATION OF ERBB4 SIGNALING	9	6.06e-01	0.099200	9.69e-01
REACTOME RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION	22	6.08e-01	-0.063200	9.69e-01
REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	91	6.08e-01	-0.031100	9.69e-01
REACTOME INITIATION OF NUCLEAR ENVELOPE NE REFORMATION	18	6.09e-01	-0.069700	9.69e-01
REACTOME PHYSIOLOGICAL FACTORS	14	6.09e-01	-0.078900	9.69e-01
REACTOME INTRAFLAGELLAR TRANSPORT	50	6.09e-01	-0.041800	9.69e-01
REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	13	6.10e-01	-0.081700	9.69e-01
REACTOME SIGNALING BY NTRK2 TRKB	25	6.10e-01	-0.059000	9.69e-01
REACTOME AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY	8	6.10e-01	-0.104000	9.69e-01
REACTOME REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION	9	6.12e-01	-0.097700	9.69e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	28	6.12e-01	0.055300	9.69e-01
REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE	5	6.13e-01	0.131000	9.69e-01
REACTOME REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO	10	6.14e-01	0.092100	9.69e-01
REACTOME HYALURONAN BIOSYNTHESIS AND EXPORT	5	6.15e-01	-0.130000	9.69e-01
REACTOME PI5P REGULATES TP53 ACETYLATION	9	6.15e-01	0.096700	9.69e-01
REACTOME P75NTR SIGNALS VIA NF KB	15	6.16e-01	0.074900	9.69e-01
REACTOME DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING	61	6.16e-01	0.037100	9.69e-01
REACTOME SODIUM PROTON EXCHANGERS	7	6.16e-01	0.109000	9.69e-01
REACTOME CELL CELL JUNCTION ORGANIZATION	64	6.16e-01	0.036200	9.69e-01
REACTOME GENERATION OF SECOND MESSENGER MOLECULES	30	6.17e-01	-0.052700	9.69e-01
REACTOME ORGANIC ANION TRANSPORTERS	10	6.17e-01	-0.091200	9.69e-01
REACTOME ARMS MEDIATED ACTIVATION	7	6.20e-01	-0.108000	9.71e-01
REACTOME SCAVENGING OF HEME FROM PLASMA	13	6.21e-01	0.079300	9.71e-01
REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS	8	6.21e-01	-0.101000	9.71e-01
REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX	85	6.22e-01	0.030900	9.71e-01
REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	31	6.22e-01	0.051100	9.71e-01
REACTOME BETA DEFENSINS	27	6.23e-01	0.054600	9.71e-01
REACTOME HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE	43	6.24e-01	-0.043300	9.71e-01
REACTOME TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS	55	6.24e-01	0.038200	9.71e-01
REACTOME RUNX3 REGULATES P14 ARF	10	6.25e-01	0.089300	9.71e-01
REACTOME MEIOSIS	110	6.25e-01	0.026900	9.71e-01
REACTOME RHO GTPASES ACTIVATE ROCKS	19	6.26e-01	-0.064600	9.71e-01
REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION	20	6.27e-01	-0.062800	9.71e-01
REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES	21	6.27e-01	0.061200	9.71e-01
REACTOME APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS	87	6.28e-01	0.030100	9.71e-01
REACTOME DEX H BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION	7	6.28e-01	-0.106000	9.71e-01
REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS	6	6.28e-01	-0.114000	9.71e-01
REACTOME INTERLEUKIN 23 SIGNALING	9	6.29e-01	0.093100	9.71e-01
REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	44	6.29e-01	-0.042100	9.71e-01
REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	296	6.30e-01	-0.016300	9.72e-01
REACTOME SIGNALING BY EGFR	49	6.32e-01	-0.039600	9.72e-01
REACTOME GLUCOSE METABOLISM	90	6.35e-01	0.029000	9.72e-01
REACTOME INTERLEUKIN 6 FAMILY SIGNALING	24	6.35e-01	-0.056000	9.72e-01
REACTOME VLDL CLEARANCE	6	6.35e-01	0.112000	9.72e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE	8	6.35e-01	0.096800	9.72e-01
REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX	15	6.35e-01	0.070700	9.72e-01
REACTOME DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX	83	6.36e-01	-0.030100	9.72e-01
REACTOME DEFECTIVE CHST6 CAUSES MCDC1	8	6.36e-01	0.096600	9.72e-01
REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION	10	6.37e-01	-0.086100	9.72e-01
REACTOME NEGATIVE REGULATION OF NOTCH4 SIGNALING	53	6.38e-01	0.037400	9.72e-01
REACTOME UPTAKE AND FUNCTION OF ANTHRAX TOXINS	11	6.38e-01	-0.082000	9.72e-01
REACTOME METAL ION SLC TRANSPORTERS	23	6.38e-01	0.056600	9.72e-01
REACTOME SODIUM CALCIUM EXCHANGERS	11	6.39e-01	-0.081600	9.72e-01
REACTOME TOXICITY OF BOTULINUM TOXIN TYPE D BOTD	5	6.39e-01	0.121000	9.72e-01
REACTOME DISEASES OF BASE EXCISION REPAIR	5	6.40e-01	0.121000	9.72e-01
REACTOME PI3K EVENTS IN ERBB2 SIGNALING	16	6.42e-01	-0.067100	9.72e-01
REACTOME RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION	6	6.44e-01	0.109000	9.72e-01
REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	30	6.44e-01	-0.048700	9.72e-01
REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	15	6.44e-01	-0.068800	9.72e-01
REACTOME INTESTINAL ABSORPTION	5	6.46e-01	-0.119000	9.72e-01
REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21	59	6.47e-01	0.034500	9.72e-01
REACTOME HEME SIGNALING	47	6.48e-01	-0.038500	9.72e-01
REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	9	6.48e-01	0.087800	9.72e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX IN CANCER	8	6.48e-01	-0.093100	9.72e-01
REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	7	6.50e-01	-0.099100	9.72e-01
REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	45	6.50e-01	0.039000	9.72e-01
REACTOME GOLGI TO ER RETROGRADE TRANSPORT	132	6.51e-01	-0.022800	9.72e-01
REACTOME INSULIN PROCESSING	24	6.51e-01	0.053400	9.72e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION TERMINATION	23	6.52e-01	0.054400	9.72e-01
REACTOME SENSORY PROCESSING OF SOUND	72	6.56e-01	0.030400	9.72e-01
REACTOME PENTOSE PHOSPHATE PATHWAY	12	6.56e-01	-0.074300	9.72e-01
REACTOME MULTIFUNCTIONAL ANION EXCHANGERS	9	6.56e-01	0.085700	9.72e-01
REACTOME TRIGLYCERIDE CATABOLISM	23	6.56e-01	0.053600	9.72e-01
REACTOME SELECTIVE AUTOPHAGY	79	6.58e-01	0.028800	9.72e-01
REACTOME RND1 GTPASE CYCLE	41	6.58e-01	-0.040000	9.72e-01
REACTOME RESPONSE TO METAL IONS	14	6.58e-01	-0.068300	9.72e-01
REACTOME SIGNALING BY NTRK3 TRKC	17	6.58e-01	-0.061900	9.72e-01
REACTOME CHOLINE CATABOLISM	6	6.58e-01	0.104000	9.72e-01
REACTOME NUCLEAR PORE COMPLEX NPC DISASSEMBLY	36	6.59e-01	0.042600	9.72e-01
REACTOME ASSEMBLY OF THE HIV VIRION	16	6.60e-01	0.063600	9.72e-01
REACTOME CLATHRIN MEDIATED ENDOCYTOSIS	139	6.60e-01	-0.021600	9.72e-01
REACTOME CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN	45	6.60e-01	-0.037900	9.72e-01
REACTOME SIGNALING BY PTK6	54	6.60e-01	-0.034600	9.72e-01
REACTOME MOLYBDENUM COFACTOR BIOSYNTHESIS	6	6.61e-01	0.104000	9.72e-01
REACTOME EPH EPHRIN SIGNALING	90	6.61e-01	-0.026700	9.72e-01
REACTOME MATURATION OF SARS COV 2 SPIKE PROTEIN	35	6.62e-01	0.042700	9.72e-01
REACTOME TOLL LIKE RECEPTOR CASCADES	158	6.62e-01	-0.020100	9.72e-01
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	81	6.63e-01	-0.028000	9.72e-01
REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	30	6.63e-01	-0.046000	9.72e-01
REACTOME NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS	11	6.63e-01	-0.075800	9.72e-01
REACTOME WAX AND PLASMALOGEN BIOSYNTHESIS	5	6.64e-01	-0.112000	9.72e-01
REACTOME DRUG ADME	103	6.65e-01	0.024700	9.72e-01
REACTOME COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING	38	6.65e-01	-0.040600	9.72e-01
REACTOME DEUBIQUITINATION	260	6.65e-01	0.015600	9.72e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE	74	6.65e-01	0.029100	9.72e-01
REACTOME DEGRADATION OF GLI1 BY THE PROTEASOME	59	6.66e-01	-0.032400	9.72e-01
REACTOME SUPPRESSION OF PHAGOSOMAL MATURATION	13	6.67e-01	-0.068900	9.72e-01
REACTOME PTK6 PROMOTES HIF1A STABILIZATION	6	6.68e-01	0.101000	9.72e-01
REACTOME SIGNALING BY WNT IN CANCER	32	6.68e-01	-0.043800	9.72e-01
REACTOME SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER	54	6.69e-01	-0.033700	9.72e-01
REACTOME INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	28	6.69e-01	-0.046700	9.72e-01
REACTOME NEGATIVE REGULATION OF MET ACTIVITY	20	6.70e-01	0.055100	9.72e-01
REACTOME ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS	20	6.70e-01	0.055000	9.72e-01
REACTOME NEGATIVE REGULATION OF FLT3	15	6.70e-01	-0.063500	9.72e-01
REACTOME CATION COUPLED CHLORIDE COTRANSPORTERS	7	6.71e-01	-0.092700	9.72e-01
REACTOME SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS	74	6.71e-01	-0.028500	9.72e-01
REACTOME RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION	8	6.71e-01	-0.086600	9.72e-01
REACTOME PRE NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM	6	6.71e-01	0.100000	9.72e-01
REACTOME MTORC1 MEDIATED SIGNALLING	23	6.72e-01	0.051100	9.72e-01
REACTOME DISSOLUTION OF FIBRIN CLOT	13	6.74e-01	-0.067500	9.74e-01
REACTOME CARGO CONCENTRATION IN THE ER	32	6.74e-01	0.043000	9.74e-01
REACTOME INTRA GOLGI TRAFFIC	43	6.75e-01	-0.036900	9.74e-01
REACTOME EPHRIN SIGNALING	17	6.76e-01	-0.058600	9.74e-01
REACTOME ACTIVATION OF CASPASES THROUGH APOPTOSOME MEDIATED CLEAVAGE	5	6.76e-01	-0.108000	9.74e-01
REACTOME IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS	17	6.78e-01	-0.058200	9.74e-01
REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING	34	6.78e-01	0.041200	9.74e-01
REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	9	6.78e-01	0.079900	9.74e-01
REACTOME ASPARTATE AND ASPARAGINE METABOLISM	11	6.79e-01	-0.072200	9.74e-01
REACTOME INTERLEUKIN 12 SIGNALING	43	6.81e-01	0.036300	9.74e-01
REACTOME OTHER INTERLEUKIN SIGNALING	24	6.82e-01	0.048300	9.74e-01
REACTOME MITOTIC G2 G2 M PHASES	194	6.82e-01	0.017100	9.74e-01
REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	20	6.83e-01	-0.052800	9.74e-01
REACTOME DNA DAMAGE RECOGNITION IN GG NER	36	6.83e-01	0.039300	9.74e-01
REACTOME RETINOID CYCLE DISEASE EVENTS	11	6.84e-01	0.071000	9.74e-01
REACTOME TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY	30	6.84e-01	0.043000	9.74e-01
REACTOME DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE	17	6.85e-01	-0.056800	9.74e-01
REACTOME RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX	29	6.86e-01	-0.043300	9.74e-01
REACTOME SIGNALING BY MET	78	6.87e-01	-0.026400	9.74e-01
REACTOME SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX	15	6.88e-01	0.059900	9.74e-01
REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	21	6.88e-01	0.050600	9.74e-01
REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION	145	6.91e-01	0.019100	9.74e-01
REACTOME NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION	20	6.91e-01	-0.051300	9.74e-01
REACTOME PYROPTOSIS	27	6.92e-01	0.044000	9.74e-01
REACTOME FLT3 SIGNALING IN DISEASE	28	6.92e-01	-0.043200	9.74e-01
REACTOME CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER	25	6.92e-01	-0.045700	9.74e-01
REACTOME GLYCOGEN STORAGE DISEASES	15	6.93e-01	0.058900	9.74e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX3	94	6.94e-01	0.023400	9.74e-01
REACTOME SHC1 EVENTS IN ERBB2 SIGNALING	22	6.95e-01	-0.048200	9.74e-01
REACTOME RUNX2 REGULATES BONE DEVELOPMENT	29	6.96e-01	-0.041900	9.74e-01
REACTOME SEROTONIN RECEPTORS	11	6.96e-01	0.067900	9.74e-01
REACTOME CELL JUNCTION ORGANIZATION	89	6.97e-01	0.023900	9.74e-01
REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	16	6.97e-01	0.056200	9.74e-01
REACTOME TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE	39	6.98e-01	0.035900	9.74e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS	11	6.98e-01	0.067500	9.74e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH PI3K	6	6.99e-01	0.091300	9.74e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1	16	6.99e-01	0.055900	9.74e-01
REACTOME SIALIC ACID METABOLISM	33	6.99e-01	-0.038900	9.74e-01
REACTOME GLYCOLYSIS	70	6.99e-01	0.026700	9.74e-01
REACTOME PECAM1 INTERACTIONS	12	7.00e-01	-0.064100	9.74e-01
REACTOME PROTEIN METHYLATION	17	7.01e-01	0.053800	9.74e-01
REACTOME PROSTANOID LIGAND RECEPTORS	9	7.01e-01	0.073900	9.74e-01
REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	9	7.01e-01	-0.073800	9.74e-01
REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	11	7.02e-01	0.066700	9.74e-01
REACTOME PEPTIDE HORMONE BIOSYNTHESIS	13	7.02e-01	-0.061200	9.74e-01
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION	1356	7.03e-01	-0.006180	9.74e-01
REACTOME SIGNALING BY THE B CELL RECEPTOR BCR	106	7.03e-01	-0.021400	9.74e-01
REACTOME INACTIVATION OF CSF3 G CSF SIGNALING	25	7.03e-01	-0.044100	9.74e-01
REACTOME SIGNALING BY NOTCH1 T 7 9 NOTCH1 M1580 K2555 TRANSLOCATION MUTANT	7	7.04e-01	-0.083000	9.74e-01
REACTOME FERTILIZATION	26	7.04e-01	-0.043000	9.74e-01
REACTOME RHOH GTPASE CYCLE	37	7.05e-01	-0.036000	9.74e-01
REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS	16	7.05e-01	-0.054600	9.74e-01
REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	69	7.07e-01	0.026200	9.74e-01
REACTOME PEROXISOMAL PROTEIN IMPORT	62	7.07e-01	0.027600	9.74e-01
REACTOME RHOBTB GTPASE CYCLE	34	7.07e-01	-0.037200	9.74e-01
REACTOME DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15	8	7.07e-01	0.076700	9.74e-01
REACTOME G1 S DNA DAMAGE CHECKPOINTS	67	7.09e-01	0.026400	9.74e-01
REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS	15	7.09e-01	-0.055700	9.74e-01
REACTOME SIGNALING BY CSF1 M CSF IN MYELOID CELLS	30	7.09e-01	-0.039300	9.74e-01
REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3	59	7.09e-01	0.028100	9.74e-01
REACTOME DERMATAN SULFATE BIOSYNTHESIS	10	7.10e-01	0.067900	9.74e-01
REACTOME CHYLOMICRON ASSEMBLY	10	7.10e-01	0.067900	9.74e-01
REACTOME GLYCOSAMINOGLYCAN METABOLISM	118	7.10e-01	0.019800	9.74e-01
REACTOME METABOLISM OF AMINE DERIVED HORMONES	17	7.12e-01	0.051800	9.75e-01
REACTOME NONCANONICAL ACTIVATION OF NOTCH3	8	7.12e-01	-0.075400	9.75e-01
REACTOME N GLYCAN ANTENNAE ELONGATION	15	7.13e-01	-0.054900	9.75e-01
REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES	78	7.13e-01	0.024100	9.75e-01
REACTOME SEMA4D IN SEMAPHORIN SIGNALING	24	7.14e-01	0.043300	9.75e-01
REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS	68	7.15e-01	-0.025600	9.75e-01
REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY	5	7.15e-01	-0.094400	9.75e-01
REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	59	7.17e-01	0.027300	9.76e-01
REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	18	7.18e-01	0.049100	9.77e-01
REACTOME GLUCAGON TYPE LIGAND RECEPTORS	32	7.20e-01	-0.036700	9.77e-01
REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	14	7.20e-01	-0.055300	9.77e-01
REACTOME FCERI MEDIATED NF KB ACTIVATION	78	7.21e-01	-0.023400	9.77e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST	18	7.23e-01	-0.048300	9.77e-01
REACTOME ESTABLISHMENT OF SISTER CHROMATID COHESION	9	7.23e-01	0.068200	9.77e-01
REACTOME MAPK1 ERK2 ACTIVATION	9	7.23e-01	0.068100	9.77e-01
REACTOME SUMOYLATION OF IMMUNE RESPONSE PROTEINS	10	7.24e-01	-0.064600	9.77e-01
REACTOME CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS	19	7.24e-01	0.046900	9.77e-01
REACTOME SEROTONIN NEUROTRANSMITTER RELEASE CYCLE	17	7.24e-01	0.049400	9.77e-01
REACTOME SIGNALING BY RNF43 MUTANTS	8	7.26e-01	-0.071600	9.77e-01
REACTOME ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN	13	7.27e-01	-0.056000	9.77e-01
REACTOME CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY	25	7.29e-01	0.040000	9.77e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	14	7.30e-01	-0.053300	9.77e-01
REACTOME PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1	9	7.30e-01	0.066400	9.77e-01
REACTOME INTERLEUKIN RECEPTOR SHC SIGNALING	24	7.30e-01	-0.040600	9.77e-01
REACTOME NRAGE SIGNALS DEATH THROUGH JNK	53	7.31e-01	-0.027300	9.77e-01
REACTOME SPRY REGULATION OF FGF SIGNALING	16	7.32e-01	-0.049500	9.77e-01
REACTOME UBIQUINOL BIOSYNTHESIS	8	7.32e-01	0.069900	9.77e-01
REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP	104	7.33e-01	0.019400	9.77e-01
REACTOME ATORVASTATIN ADME	9	7.34e-01	-0.065400	9.77e-01
REACTOME RHO GTPASES ACTIVATE PKNS	86	7.34e-01	-0.021200	9.77e-01
REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	15	7.35e-01	-0.050500	9.77e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY	19	7.35e-01	0.044800	9.77e-01
REACTOME TELOMERE C STRAND SYNTHESIS INITIATION	12	7.35e-01	0.056400	9.77e-01
REACTOME ACYL CHAIN REMODELING OF DAG AND TAG	5	7.36e-01	-0.086900	9.77e-01
REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	29	7.37e-01	0.036100	9.77e-01
REACTOME KINESINS	59	7.38e-01	0.025100	9.77e-01
REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	24	7.41e-01	-0.039000	9.77e-01
REACTOME NUCLEAR SIGNALING BY ERBB4	32	7.41e-01	-0.033800	9.77e-01
REACTOME THYROXINE BIOSYNTHESIS	10	7.42e-01	0.060100	9.77e-01
REACTOME GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	34	7.42e-01	0.032600	9.77e-01
REACTOME TRAF6 MEDIATED NF KB ACTIVATION	24	7.43e-01	0.038700	9.77e-01
REACTOME TP53 REGULATES METABOLIC GENES	81	7.43e-01	0.021100	9.77e-01
REACTOME COPI MEDIATED ANTEROGRADE TRANSPORT	101	7.43e-01	-0.018900	9.77e-01
REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX	21	7.43e-01	-0.041300	9.77e-01
REACTOME REGULATION OF TP53 ACTIVITY	156	7.43e-01	0.015200	9.77e-01
REACTOME LIGAND RECEPTOR INTERACTIONS	8	7.43e-01	0.066800	9.77e-01
REACTOME AMINO ACID CONJUGATION	9	7.46e-01	-0.062400	9.77e-01
REACTOME ER QUALITY CONTROL COMPARTMENT ERQC	21	7.46e-01	-0.040800	9.77e-01
REACTOME SMAC XIAP REGULATED APOPTOTIC RESPONSE	7	7.47e-01	-0.070500	9.77e-01
REACTOME ER TO GOLGI ANTEROGRADE TRANSPORT	152	7.47e-01	-0.015200	9.77e-01
REACTOME SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE	91	7.49e-01	0.019400	9.77e-01
REACTOME COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC	98	7.50e-01	0.018600	9.77e-01
REACTOME ASPARAGINE N LINKED GLYCOSYLATION	299	7.52e-01	0.010600	9.77e-01
REACTOME KEAP1 NFE2L2 PATHWAY	104	7.52e-01	-0.017900	9.77e-01
REACTOME LOSS OF FUNCTION OF SMAD2 3 IN CANCER	7	7.53e-01	-0.068800	9.77e-01
REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III	31	7.53e-01	-0.032600	9.77e-01
REACTOME INTEGRATION OF PROVIRUS	9	7.54e-01	-0.060400	9.77e-01
REACTOME RHO GTPASES ACTIVATE PAKS	19	7.54e-01	-0.041600	9.77e-01
REACTOME SPERM MOTILITY AND TAXES	9	7.58e-01	-0.059400	9.77e-01
REACTOME NEUROTRANSMITTER RELEASE CYCLE	48	7.58e-01	0.025700	9.77e-01
REACTOME CONSTITUTIVE SIGNALING BY EGFRVIII	15	7.58e-01	-0.045900	9.77e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION	29	7.58e-01	-0.033000	9.77e-01
REACTOME MUCOPOLYSACCHARIDOSES	10	7.59e-01	0.056100	9.77e-01
REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	20	7.59e-01	0.039700	9.77e-01
REACTOME ENDOSOMAL VACUOLAR PATHWAY	11	7.59e-01	0.053300	9.77e-01
REACTOME ESTROGEN DEPENDENT GENE EXPRESSION	140	7.60e-01	-0.015000	9.77e-01
REACTOME PARACETAMOL ADME	26	7.61e-01	0.034400	9.77e-01
REACTOME DEFECTIVE CHST3 CAUSES SEDCJD	7	7.61e-01	0.066300	9.77e-01
REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION	68	7.61e-01	0.021300	9.77e-01
REACTOME CALNEXIN CALRETICULIN CYCLE	26	7.62e-01	-0.034400	9.77e-01
REACTOME PURINE CATABOLISM	17	7.62e-01	0.042500	9.77e-01
REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	14	7.62e-01	-0.046700	9.77e-01
REACTOME NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS	25	7.62e-01	0.035000	9.77e-01
REACTOME SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS	14	7.62e-01	-0.046700	9.77e-01
REACTOME INFLAMMASOMES	21	7.63e-01	-0.038000	9.77e-01
REACTOME DNA STRAND ELONGATION	31	7.63e-01	0.031300	9.77e-01
REACTOME INTEGRIN CELL SURFACE INTERACTIONS	83	7.63e-01	0.019100	9.77e-01
REACTOME FANCONI ANEMIA PATHWAY	35	7.63e-01	0.029400	9.77e-01
REACTOME DEFECTIVE CHSY1 CAUSES TPBS	7	7.64e-01	-0.065600	9.77e-01
REACTOME IRF3 MEDIATED INDUCTION OF TYPE I IFN	13	7.64e-01	0.048100	9.77e-01
REACTOME TNFR1 INDUCED PROAPOPTOTIC SIGNALING	23	7.64e-01	0.036100	9.77e-01
REACTOME KERATAN SULFATE KERATIN METABOLISM	34	7.66e-01	-0.029500	9.77e-01
REACTOME ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE	9	7.66e-01	-0.057300	9.77e-01
REACTOME RUNX3 REGULATES YAP1 MEDIATED TRANSCRIPTION	8	7.69e-01	-0.060000	9.77e-01
REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS	8	7.69e-01	0.059900	9.77e-01
REACTOME METHYLATION	14	7.70e-01	0.045200	9.77e-01
REACTOME TELOMERE MAINTENANCE	106	7.70e-01	0.016400	9.77e-01
REACTOME TERMINATION OF TRANSLESION DNA SYNTHESIS	32	7.70e-01	0.029800	9.77e-01
REACTOME SYNAPTIC ADHESION LIKE MOLECULES	19	7.72e-01	-0.038400	9.77e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN	13	7.73e-01	0.046300	9.77e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES	29	7.74e-01	0.030800	9.77e-01
REACTOME VLDLR INTERNALISATION AND DEGRADATION	16	7.75e-01	0.041300	9.77e-01
REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC	198	7.76e-01	-0.011700	9.77e-01
REACTOME SHC1 EVENTS IN EGFR SIGNALING	14	7.77e-01	-0.043700	9.77e-01
REACTOME MIRO GTPASE CYCLE	8	7.78e-01	-0.057500	9.77e-01
REACTOME CIPROFLOXACIN ADME	5	7.80e-01	0.072300	9.77e-01
REACTOME HYALURONAN METABOLISM	17	7.80e-01	-0.039100	9.77e-01
REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	23	7.80e-01	0.033600	9.77e-01
REACTOME VITAMIN B1 THIAMIN METABOLISM	5	7.80e-01	-0.072000	9.77e-01
REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS	63	7.80e-01	0.020300	9.77e-01
REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	91	7.80e-01	0.016900	9.77e-01
REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	122	7.81e-01	-0.014600	9.77e-01
REACTOME DEFECTIVE CHST14 CAUSES EDS MUSCULOCONTRACTURAL TYPE	7	7.83e-01	-0.060100	9.77e-01
REACTOME METABOLISM OF FOLATE AND PTERINES	17	7.83e-01	0.038600	9.77e-01
REACTOME PRE NOTCH EXPRESSION AND PROCESSING	112	7.83e-01	-0.015000	9.77e-01
REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	15	7.84e-01	-0.040900	9.77e-01
REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	23	7.84e-01	-0.033000	9.77e-01
REACTOME DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE	30	7.84e-01	-0.028900	9.77e-01
REACTOME ACTIVATION OF C3 AND C5	6	7.85e-01	-0.064500	9.77e-01
REACTOME REPRODUCTION	136	7.85e-01	0.013500	9.77e-01
REACTOME FGFR2 ALTERNATIVE SPLICING	27	7.86e-01	-0.030200	9.77e-01
REACTOME RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK	47	7.86e-01	-0.022900	9.77e-01
REACTOME HEDGEHOG ON STATE	85	7.87e-01	-0.017000	9.77e-01
REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	14	7.87e-01	0.041600	9.77e-01
REACTOME AURKA ACTIVATION BY TPX2	69	7.88e-01	0.018800	9.77e-01
REACTOME SUMOYLATION OF RNA BINDING PROTEINS	47	7.88e-01	0.022700	9.77e-01
REACTOME NUCLEAR EVENTS MEDIATED BY NFE2L2	77	7.88e-01	0.017700	9.77e-01
REACTOME LRR FLII INTERACTING PROTEIN 1 LRRFIP1 ACTIVATES TYPE I IFN PRODUCTION	5	7.89e-01	-0.069200	9.77e-01
REACTOME CELLULAR RESPONSE TO HYPOXIA	74	7.89e-01	0.018000	9.77e-01
REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	36	7.89e-01	0.025700	9.77e-01
REACTOME MATURATION OF SARS COV 2 NUCLEOPROTEIN	15	7.89e-01	-0.039800	9.77e-01
REACTOME AGGREPHAGY	42	7.89e-01	0.023800	9.77e-01
REACTOME ARYL HYDROCARBON RECEPTOR SIGNALLING	6	7.90e-01	0.062900	9.77e-01
REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	118	7.90e-01	-0.014200	9.77e-01
REACTOME CS DS DEGRADATION	12	7.91e-01	-0.044300	9.77e-01
REACTOME REGULATION OF BETA CELL DEVELOPMENT	41	7.91e-01	0.024000	9.77e-01
REACTOME CHYLOMICRON CLEARANCE	5	7.91e-01	-0.068300	9.77e-01
REACTOME DEFECTS IN VITAMIN AND COFACTOR METABOLISM	21	7.91e-01	0.033400	9.77e-01
REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS	81	7.91e-01	0.017000	9.77e-01
REACTOME RUNX3 REGULATES NOTCH SIGNALING	13	7.93e-01	0.042100	9.77e-01
REACTOME SIGNALING BY NOTCH4	80	7.93e-01	0.017000	9.77e-01
REACTOME CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND	16	7.93e-01	0.037800	9.77e-01
REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	123	7.97e-01	-0.013400	9.77e-01
REACTOME TNFR2 NON CANONICAL NF KB PATHWAY	96	7.97e-01	0.015200	9.77e-01
REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF	53	7.98e-01	-0.020400	9.77e-01
REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	8	7.98e-01	0.052300	9.77e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH CDK5	6	7.98e-01	-0.060400	9.77e-01
REACTOME SIGNALING BY ERBB2 IN CANCER	26	7.98e-01	-0.029000	9.77e-01
REACTOME VLDL ASSEMBLY	5	7.98e-01	-0.066000	9.77e-01
REACTOME HOST INTERACTIONS OF HIV FACTORS	127	7.99e-01	0.013100	9.77e-01
REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	89	7.99e-01	0.015600	9.77e-01
REACTOME DEGRADATION OF CYSTEINE AND HOMOCYSTEINE	15	8.00e-01	-0.037900	9.77e-01
REACTOME CARDIAC CONDUCTION	125	8.00e-01	0.013100	9.77e-01
REACTOME REGULATION OF LIPID METABOLISM BY PPARALPHA	115	8.00e-01	0.013700	9.77e-01
REACTOME LGI ADAM INTERACTIONS	14	8.01e-01	0.038900	9.77e-01
REACTOME SIGNALING BY FGFR2 IIIA TM	19	8.03e-01	-0.033100	9.77e-01
REACTOME REGULATION OF NF KAPPA B SIGNALING	17	8.03e-01	0.034900	9.77e-01
REACTOME DEADENYLATION OF MRNA	25	8.04e-01	0.028700	9.77e-01
REACTOME SUPPRESSION OF APOPTOSIS	7	8.04e-01	0.054200	9.77e-01
REACTOME EICOSANOID LIGAND BINDING RECEPTORS	14	8.04e-01	-0.038300	9.77e-01
REACTOME NRCAM INTERACTIONS	6	8.05e-01	-0.058300	9.77e-01
REACTOME FORMATION OF LATERAL PLATE MESODERM	5	8.06e-01	-0.063400	9.77e-01
REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	73	8.07e-01	0.016500	9.77e-01
REACTOME RHOA GTPASE CYCLE	142	8.07e-01	-0.011900	9.77e-01
REACTOME AMINE LIGAND BINDING RECEPTORS	40	8.07e-01	0.022300	9.77e-01
REACTOME METABOLISM OF VITAMINS AND COFACTORS	185	8.07e-01	0.010400	9.77e-01
REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	17	8.08e-01	0.034100	9.77e-01
REACTOME SYNTHESIS OF PE	13	8.09e-01	0.038800	9.77e-01
REACTOME ACTIVATION OF SMO	18	8.09e-01	0.032900	9.77e-01
REACTOME PLASMA LIPOPROTEIN CLEARANCE	37	8.10e-01	-0.022900	9.77e-01
REACTOME PROLACTIN RECEPTOR SIGNALING	15	8.10e-01	-0.035800	9.77e-01
REACTOME SIGNALING BY LRP5 MUTANTS	6	8.10e-01	-0.056700	9.77e-01
REACTOME NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	19	8.11e-01	0.031700	9.77e-01
REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE	93	8.12e-01	-0.014300	9.77e-01
REACTOME ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY	5	8.12e-01	0.061500	9.77e-01
REACTOME REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM	11	8.12e-01	-0.041400	9.77e-01
REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	14	8.12e-01	-0.036600	9.77e-01
REACTOME MISCELLANEOUS SUBSTRATES	12	8.14e-01	0.039200	9.77e-01
REACTOME FORMATION OF TC NER PRE INCISION COMPLEX	51	8.15e-01	-0.019000	9.77e-01
REACTOME RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS	9	8.15e-01	-0.045000	9.77e-01
REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS	113	8.16e-01	0.012700	9.77e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH RAS	8	8.17e-01	-0.047300	9.77e-01
REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	21	8.18e-01	0.029100	9.77e-01
REACTOME VESICLE MEDIATED TRANSPORT	642	8.18e-01	-0.005330	9.77e-01
REACTOME NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	24	8.18e-01	-0.027200	9.77e-01
REACTOME G2 M DNA REPLICATION CHECKPOINT	5	8.18e-01	-0.059400	9.77e-01
REACTOME RAF INDEPENDENT MAPK1 3 ACTIVATION	22	8.18e-01	0.028300	9.77e-01
REACTOME TELOMERE EXTENSION BY TELOMERASE	22	8.19e-01	0.028200	9.77e-01
REACTOME CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND	9	8.20e-01	0.043700	9.77e-01
REACTOME MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION	15	8.21e-01	0.033700	9.77e-01
REACTOME GAP JUNCTION DEGRADATION	12	8.22e-01	-0.037600	9.77e-01
REACTOME GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER	25	8.22e-01	-0.026000	9.77e-01
REACTOME FIBRONECTIN MATRIX FORMATION	6	8.22e-01	0.053100	9.77e-01
REACTOME DEFECTIVE B4GALT1 CAUSES B4GALT1 CDG CDG 2D	8	8.23e-01	-0.045700	9.77e-01
REACTOME MATURATION OF SARS COV 1 SPIKE PROTEIN	5	8.23e-01	0.057700	9.77e-01
REACTOME PHASE II CONJUGATION OF COMPOUNDS	102	8.23e-01	0.012800	9.77e-01
REACTOME AQUAPORIN MEDIATED TRANSPORT	51	8.25e-01	-0.017900	9.77e-01
REACTOME DEATH RECEPTOR SIGNALING	143	8.26e-01	0.010700	9.77e-01
REACTOME SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS	16	8.26e-01	0.031800	9.77e-01
REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	23	8.26e-01	0.026500	9.77e-01
REACTOME PRE NOTCH PROCESSING IN GOLGI	18	8.26e-01	-0.029900	9.77e-01
REACTOME RHOT1 GTPASE CYCLE	5	8.27e-01	-0.056500	9.77e-01
REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	62	8.28e-01	0.015900	9.77e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1	20	8.29e-01	0.027900	9.77e-01
REACTOME REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR	11	8.29e-01	-0.037500	9.77e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS	121	8.30e-01	0.011300	9.77e-01
REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	10	8.30e-01	-0.039200	9.77e-01
REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION	23	8.30e-01	0.025800	9.77e-01
REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE	19	8.31e-01	-0.028300	9.77e-01
REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS	12	8.32e-01	0.035400	9.78e-01
REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	49	8.33e-01	0.017500	9.78e-01
REACTOME MET PROMOTES CELL MOTILITY	41	8.33e-01	0.019000	9.78e-01
REACTOME THE ACTIVATION OF ARYLSULFATASES	8	8.34e-01	-0.042700	9.78e-01
REACTOME NUCLEAR ENVELOPE BREAKDOWN	52	8.35e-01	-0.016700	9.78e-01
REACTOME BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS	10	8.35e-01	0.038000	9.78e-01
REACTOME REGULATION OF FZD BY UBIQUITINATION	21	8.35e-01	0.026200	9.78e-01
REACTOME DNA DAMAGE BYPASS	47	8.36e-01	0.017500	9.78e-01
REACTOME RAB REGULATION OF TRAFFICKING	110	8.38e-01	-0.011300	9.79e-01
REACTOME COMPLEMENT CASCADE	54	8.40e-01	-0.015900	9.79e-01
REACTOME BINDING OF TCF LEF CTNNB1 TO TARGET GENE PROMOTERS	8	8.41e-01	-0.041100	9.79e-01
REACTOME APEX1 INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	7	8.41e-01	0.043700	9.79e-01
REACTOME NEGATIVE REGULATION OF MAPK PATHWAY	41	8.42e-01	-0.018000	9.79e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES	12	8.42e-01	-0.033300	9.79e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES	43	8.42e-01	-0.017600	9.79e-01
REACTOME DEADENYLATION DEPENDENT MRNA DECAY	56	8.42e-01	0.015400	9.79e-01
REACTOME NOD1 2 SIGNALING PATHWAY	33	8.42e-01	0.020000	9.79e-01
REACTOME P38MAPK EVENTS	13	8.43e-01	-0.031700	9.79e-01
REACTOME METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS	122	8.44e-01	-0.010300	9.79e-01
REACTOME RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES	16	8.46e-01	0.028100	9.79e-01
REACTOME REGULATION OF TP53 EXPRESSION AND DEGRADATION	37	8.46e-01	0.018400	9.79e-01
REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES	34	8.47e-01	-0.019100	9.79e-01
REACTOME SYNTHESIS OF UDP N ACETYL GLUCOSAMINE	7	8.48e-01	-0.042000	9.79e-01
REACTOME STAT3 NUCLEAR EVENTS DOWNSTREAM OF ALK SIGNALING	9	8.48e-01	-0.037000	9.79e-01
REACTOME RNA POLYMERASE II TRANSCRIPTION	1336	8.48e-01	0.003120	9.79e-01
REACTOME RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES TREGS	9	8.48e-01	0.036900	9.79e-01
REACTOME BILE ACID AND BILE SALT METABOLISM	45	8.50e-01	-0.016300	9.80e-01
REACTOME PHASE 3 RAPID REPOLARISATION	8	8.50e-01	-0.038500	9.80e-01
REACTOME BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA	6	8.51e-01	0.044400	9.80e-01
REACTOME PI3K AKT ACTIVATION	9	8.51e-01	-0.036200	9.80e-01
REACTOME IRS ACTIVATION	5	8.52e-01	0.048200	9.80e-01
REACTOME MET RECEPTOR RECYCLING	10	8.52e-01	0.034000	9.80e-01
REACTOME TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX	10	8.54e-01	0.033500	9.80e-01
REACTOME N GLYCAN TRIMMING AND ELONGATION IN THE CIS GOLGI	5	8.55e-01	0.047100	9.80e-01
REACTOME INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING	103	8.55e-01	0.010400	9.80e-01
REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP	41	8.56e-01	0.016400	9.80e-01
REACTOME SIGNALING BY CSF3 G CSF	30	8.56e-01	-0.019100	9.80e-01
REACTOME RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA	7	8.59e-01	0.038800	9.80e-01
REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	38	8.59e-01	0.016600	9.80e-01
REACTOME ONCOGENE INDUCED SENESCENCE	35	8.59e-01	-0.017300	9.80e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING	25	8.60e-01	0.020400	9.80e-01
REACTOME BETA OXIDATION OF PRISTANOYL COA	9	8.60e-01	0.033900	9.80e-01
REACTOME DEGRADATION OF DVL	56	8.61e-01	0.013600	9.80e-01
REACTOME ION HOMEOSTASIS	52	8.63e-01	0.013900	9.80e-01
REACTOME SIGNALING BY ERBB2 ECD MUTANTS	16	8.63e-01	-0.025000	9.80e-01
REACTOME TRP CHANNELS	27	8.63e-01	-0.019200	9.80e-01
REACTOME COHESIN LOADING ONTO CHROMATIN	8	8.63e-01	-0.035200	9.80e-01
REACTOME ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING	23	8.63e-01	0.020800	9.80e-01
REACTOME TRANSCRIPTIONAL REGULATION BY TP53	351	8.63e-01	0.005350	9.80e-01
REACTOME TAK1 DEPENDENT IKK AND NF KAPPA B ACTIVATION	41	8.63e-01	0.015500	9.80e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG	7	8.64e-01	-0.037400	9.80e-01
REACTOME CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION	24	8.64e-01	0.020200	9.80e-01
REACTOME MUSCARINIC ACETYLCHOLINE RECEPTORS	5	8.66e-01	0.043500	9.82e-01
REACTOME MISMATCH REPAIR	15	8.68e-01	0.024800	9.82e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES	61	8.68e-01	-0.012300	9.82e-01
REACTOME TRNA MODIFICATION IN THE MITOCHONDRION	8	8.69e-01	0.033600	9.82e-01
REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION	23	8.69e-01	0.019800	9.82e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION	41	8.70e-01	0.014700	9.83e-01
REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	26	8.71e-01	0.018400	9.83e-01
REACTOME PHOSPHORYLATION OF EMI1	6	8.72e-01	0.038100	9.83e-01
REACTOME UPTAKE AND ACTIONS OF BACTERIAL TOXINS	28	8.72e-01	0.017600	9.83e-01
REACTOME FASL CD95L SIGNALING	5	8.75e-01	-0.040800	9.85e-01
REACTOME STIMULI SENSING CHANNELS	100	8.76e-01	-0.009060	9.85e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	14	8.76e-01	-0.024000	9.86e-01
REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING	45	8.78e-01	-0.013200	9.86e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	36	8.79e-01	0.014700	9.86e-01
REACTOME DEFECTIVE LFNG CAUSES SCDO3	5	8.79e-01	0.039300	9.86e-01
REACTOME NUCLEOTIDE CATABOLISM	35	8.80e-01	-0.014700	9.86e-01
REACTOME OPSINS	7	8.80e-01	-0.032900	9.86e-01
REACTOME REGULATION OF GENE EXPRESSION IN ENDOCRINE COMMITTED NEUROG3 PROGENITOR CELLS	5	8.81e-01	-0.038700	9.86e-01
REACTOME ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT	23	8.81e-01	0.018000	9.86e-01
REACTOME DISEASES OF DNA REPAIR	51	8.81e-01	0.012100	9.86e-01
REACTOME PRC2 METHYLATES HISTONES AND DNA	65	8.82e-01	0.010700	9.86e-01
REACTOME DEFECTS IN COBALAMIN B12 METABOLISM	13	8.82e-01	-0.023700	9.86e-01
REACTOME HDR THROUGH SINGLE STRAND ANNEALING SSA	37	8.84e-01	0.013900	9.86e-01
REACTOME REGULATION OF SIGNALING BY CBL	22	8.85e-01	-0.017900	9.87e-01
REACTOME INTERLEUKIN 35 SIGNALLING	12	8.86e-01	-0.023900	9.88e-01
REACTOME SIGNALING BY EGFR IN CANCER	25	8.87e-01	0.016500	9.88e-01
REACTOME INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE	20	8.89e-01	0.018000	9.88e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM	38	8.90e-01	0.013000	9.88e-01
REACTOME TNF SIGNALING	54	8.90e-01	-0.010800	9.88e-01
REACTOME SIGNALING BY LEPTIN	11	8.91e-01	0.023900	9.88e-01
REACTOME TYPE I HEMIDESMOSOME ASSEMBLY	11	8.91e-01	0.023900	9.88e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES	16	8.94e-01	-0.019200	9.88e-01
REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	10	8.94e-01	0.024200	9.88e-01
REACTOME SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER	15	8.95e-01	-0.019800	9.88e-01
REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	79	8.96e-01	0.008480	9.88e-01
REACTOME NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS	22	8.96e-01	-0.016000	9.88e-01
REACTOME ARACHIDONATE PRODUCTION FROM DAG	5	8.96e-01	0.033600	9.88e-01
REACTOME CIRCADIAN CLOCK	68	8.97e-01	-0.009090	9.88e-01
REACTOME ANDROGEN BIOSYNTHESIS	11	8.97e-01	-0.022600	9.88e-01
REACTOME RUNX2 REGULATES CHONDROCYTE MATURATION	5	8.97e-01	-0.033300	9.88e-01
REACTOME MITOCHONDRIAL UNCOUPLING	5	9.00e-01	-0.032500	9.88e-01
REACTOME DNA REPAIR	321	9.00e-01	0.004070	9.88e-01
REACTOME TOLL LIKE RECEPTOR 9 TLR9 CASCADE	100	9.00e-01	-0.007240	9.88e-01
REACTOME OXIDATIVE STRESS INDUCED SENESCENCE	118	9.00e-01	0.006670	9.88e-01
REACTOME FCGR ACTIVATION	11	9.01e-01	-0.021700	9.88e-01
REACTOME RUNX3 REGULATES BCL2L11 BIM TRANSCRIPTION	5	9.04e-01	0.031100	9.88e-01
REACTOME PI3K EVENTS IN ERBB4 SIGNALING	10	9.05e-01	-0.021800	9.88e-01
REACTOME TRIGLYCERIDE METABOLISM	35	9.05e-01	-0.011600	9.88e-01
REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	101	9.05e-01	-0.006840	9.88e-01
REACTOME REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS	15	9.08e-01	-0.017300	9.88e-01
REACTOME INFECTION WITH MYCOBACTERIUM TUBERCULOSIS	25	9.09e-01	-0.013300	9.88e-01
REACTOME REGULATION BY C FLIP	11	9.09e-01	0.019900	9.88e-01
REACTOME ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS	10	9.09e-01	-0.020800	9.88e-01
REACTOME PHENYLALANINE AND TYROSINE METABOLISM	11	9.09e-01	0.019800	9.88e-01
REACTOME GLUCONEOGENESIS	33	9.10e-01	0.011400	9.88e-01
REACTOME POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE	25	9.10e-01	-0.013000	9.88e-01
REACTOME RNA POLYMERASE II PRE TRANSCRIPTION EVENTS	77	9.10e-01	-0.007430	9.88e-01
REACTOME EGFR DOWNREGULATION	30	9.11e-01	-0.011800	9.88e-01
REACTOME O LINKED GLYCOSYLATION OF MUCINS	61	9.11e-01	0.008270	9.88e-01
REACTOME UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION	19	9.11e-01	-0.014800	9.88e-01
REACTOME RHO GTPASES ACTIVATE FORMINS	136	9.12e-01	-0.005520	9.88e-01
REACTOME FORMATION OF XYLULOSE 5 PHOSPHATE	5	9.12e-01	-0.028500	9.88e-01
REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION	35	9.13e-01	0.010700	9.88e-01
REACTOME IRAK4 DEFICIENCY TLR2 4	17	9.14e-01	0.015200	9.88e-01
REACTOME GLYCOGEN SYNTHESIS	13	9.15e-01	-0.017100	9.88e-01
REACTOME BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA	5	9.15e-01	0.027600	9.88e-01
REACTOME TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS	52	9.15e-01	0.008550	9.88e-01
REACTOME RSK ACTIVATION	5	9.16e-01	0.027200	9.88e-01
REACTOME FREE FATTY ACID RECEPTORS	5	9.17e-01	-0.027000	9.88e-01
REACTOME DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1	9	9.17e-01	0.020100	9.88e-01
REACTOME REGULATION OF IFNG SIGNALING	14	9.18e-01	-0.015900	9.88e-01
REACTOME SIGNALING BY NOTCH3	48	9.19e-01	0.008510	9.88e-01
REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA	11	9.19e-01	0.017700	9.88e-01
REACTOME NEUROTOXICITY OF CLOSTRIDIUM TOXINS	10	9.20e-01	-0.018400	9.88e-01
REACTOME INTERLEUKIN 20 FAMILY SIGNALING	25	9.21e-01	0.011400	9.88e-01
REACTOME THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT	77	9.22e-01	0.006440	9.88e-01
REACTOME PCP CE PATHWAY	91	9.22e-01	-0.005920	9.88e-01
REACTOME INTERLEUKIN 12 FAMILY SIGNALING	53	9.24e-01	-0.007620	9.88e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS	14	9.24e-01	-0.014700	9.88e-01
REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	24	9.25e-01	0.011100	9.88e-01
REACTOME TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS	26	9.26e-01	-0.010500	9.88e-01
REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	35	9.28e-01	-0.008790	9.88e-01
REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	17	9.28e-01	0.012600	9.88e-01
REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY	26	9.29e-01	0.010100	9.88e-01
REACTOME RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR	19	9.29e-01	0.011800	9.88e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD4	15	9.29e-01	-0.013200	9.88e-01
REACTOME NETRIN 1 SIGNALING	49	9.30e-01	-0.007210	9.88e-01
REACTOME FATTY ACYL COA BIOSYNTHESIS	36	9.31e-01	0.008380	9.88e-01
REACTOME TRIF MEDIATED PROGRAMMED CELL DEATH	9	9.31e-01	-0.016700	9.88e-01
REACTOME CELLULAR SENESCENCE	189	9.31e-01	-0.003650	9.88e-01
REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX	13	9.32e-01	-0.013600	9.88e-01
REACTOME NUCLEAR ENVELOPE NE REASSEMBLY	74	9.33e-01	0.005650	9.88e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS	12	9.33e-01	-0.014000	9.88e-01
REACTOME IRON UPTAKE AND TRANSPORT	56	9.34e-01	-0.006360	9.88e-01
REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT	222	9.35e-01	-0.003200	9.88e-01
REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	53	9.35e-01	0.006460	9.88e-01
REACTOME PREVENTION OF PHAGOSOMAL LYSOSOMAL FUSION	9	9.35e-01	-0.015600	9.88e-01
REACTOME TRAFFICKING OF AMPA RECEPTORS	29	9.35e-01	0.008680	9.88e-01
REACTOME ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION	28	9.36e-01	0.008820	9.88e-01
REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION	6	9.36e-01	0.019000	9.88e-01
REACTOME ERBB2 ACTIVATES PTK6 SIGNALING	13	9.36e-01	0.012900	9.88e-01
REACTOME SYNTHESIS OF DIPHTHAMIDE EEF2	8	9.36e-01	0.016400	9.88e-01
REACTOME ZINC TRANSPORTERS	15	9.36e-01	0.011900	9.88e-01
REACTOME ACTIVATION OF RAS IN B CELLS	5	9.36e-01	-0.020600	9.88e-01
REACTOME REGULATION OF RAS BY GAPS	66	9.37e-01	0.005590	9.88e-01
REACTOME CHYLOMICRON REMODELING	10	9.38e-01	0.014200	9.88e-01
REACTOME NEF MEDIATED CD8 DOWN REGULATION	7	9.38e-01	-0.016900	9.88e-01
REACTOME SIGNALING BY ERBB2	50	9.40e-01	-0.006190	9.88e-01
REACTOME PROCESSING OF INTRONLESS PRE MRNAS	19	9.41e-01	0.009820	9.88e-01
REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE	109	9.43e-01	0.003950	9.88e-01
REACTOME SYNDECAN INTERACTIONS	26	9.43e-01	0.008060	9.88e-01
REACTOME HEME DEGRADATION	15	9.44e-01	0.010600	9.88e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES	49	9.44e-01	0.005830	9.88e-01
REACTOME ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY	10	9.44e-01	-0.012800	9.88e-01
REACTOME EPH EPHRIN MEDIATED REPULSION OF CELLS	50	9.44e-01	-0.005740	9.88e-01
REACTOME RIP MEDIATED NFKB ACTIVATION VIA ZBP1	16	9.44e-01	0.010100	9.88e-01
REACTOME PEXOPHAGY	11	9.44e-01	0.012200	9.88e-01
REACTOME METABOLISM OF STEROID HORMONES	35	9.45e-01	0.006750	9.88e-01
REACTOME SYNTHESIS OF DNA	119	9.46e-01	0.003620	9.88e-01
REACTOME LDL CLEARANCE	19	9.46e-01	0.009030	9.88e-01
REACTOME FGFR1B LIGAND BINDING AND ACTIVATION	6	9.47e-01	-0.015600	9.88e-01
REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	37	9.48e-01	0.006230	9.88e-01
REACTOME HYDROLYSIS OF LPC	9	9.48e-01	-0.012600	9.88e-01
REACTOME COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING	32	9.48e-01	-0.006610	9.88e-01
REACTOME PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING	5	9.49e-01	-0.016600	9.88e-01
REACTOME SENSORY PERCEPTION OF SALTY TASTE	6	9.49e-01	-0.015100	9.88e-01
REACTOME FOXO MEDIATED TRANSCRIPTION	65	9.49e-01	0.004590	9.88e-01
REACTOME DEGRADATION OF AXIN	54	9.50e-01	-0.004910	9.88e-01
REACTOME HORMONE LIGAND BINDING RECEPTORS	12	9.51e-01	0.010300	9.88e-01
REACTOME CTLA4 INHIBITORY SIGNALING	21	9.53e-01	-0.007510	9.88e-01
REACTOME HDL ASSEMBLY	8	9.53e-01	0.012100	9.88e-01
REACTOME ETHANOL OXIDATION	12	9.53e-01	-0.009750	9.88e-01
REACTOME RAS SIGNALING DOWNSTREAM OF NF1 LOSS OF FUNCTION VARIANTS	7	9.53e-01	-0.012800	9.88e-01
REACTOME CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS	100	9.54e-01	-0.003330	9.88e-01
REACTOME POLB DEPENDENT LONG PATCH BASE EXCISION REPAIR	8	9.54e-01	0.011800	9.88e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS	6	9.54e-01	0.013500	9.88e-01
REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	17	9.54e-01	0.008030	9.88e-01
REACTOME SIGNAL TRANSDUCTION BY L1	20	9.54e-01	-0.007370	9.88e-01
REACTOME HIV ELONGATION ARREST AND RECOVERY	33	9.54e-01	0.005740	9.88e-01
REACTOME PROTEIN UBIQUITINATION	76	9.55e-01	-0.003740	9.88e-01
REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	16	9.56e-01	0.007940	9.88e-01
REACTOME G0 AND EARLY G1	27	9.58e-01	-0.005860	9.89e-01
REACTOME RHOQ GTPASE CYCLE	57	9.59e-01	-0.003960	9.89e-01
REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4	33	9.59e-01	-0.005200	9.89e-01
REACTOME VASOPRESSIN LIKE RECEPTORS	5	9.59e-01	-0.013300	9.89e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES	15	9.61e-01	-0.007300	9.90e-01
REACTOME HDR THROUGH HOMOLOGOUS RECOMBINATION HRR	66	9.63e-01	0.003330	9.90e-01
REACTOME RAB GERANYLGERANYLATION	57	9.63e-01	0.003540	9.90e-01
REACTOME METHIONINE SALVAGE PATHWAY	6	9.64e-01	-0.010700	9.90e-01
REACTOME MITOTIC TELOPHASE CYTOKINESIS	11	9.64e-01	-0.007880	9.90e-01
REACTOME ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS	5	9.64e-01	0.011600	9.90e-01
REACTOME BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA	5	9.64e-01	-0.011600	9.90e-01
REACTOME PHASE 4 RESTING MEMBRANE POTENTIAL	19	9.66e-01	0.005700	9.90e-01
REACTOME REGULATION OF BACH1 ACTIVITY	11	9.66e-01	-0.007320	9.91e-01
REACTOME HIV TRANSCRIPTION INITIATION	43	9.68e-01	-0.003580	9.91e-01
REACTOME MAPK3 ERK1 ACTIVATION	10	9.68e-01	0.007270	9.91e-01
REACTOME NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10	12	9.71e-01	0.006080	9.93e-01
REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	11	9.74e-01	-0.005740	9.95e-01
REACTOME INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION	21	9.74e-01	-0.004090	9.95e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS	9	9.76e-01	-0.005810	9.95e-01
REACTOME PREGNENOLONE BIOSYNTHESIS	12	9.76e-01	0.004970	9.95e-01
REACTOME CROSS PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS PHAGOSOMES	6	9.76e-01	0.007000	9.95e-01
REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	12	9.76e-01	0.004940	9.95e-01
REACTOME PEPTIDE HORMONE METABOLISM	84	9.77e-01	0.001790	9.95e-01
REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	183	9.78e-01	0.001180	9.95e-01
REACTOME 2 LTR CIRCLE FORMATION	7	9.79e-01	-0.005700	9.95e-01
REACTOME G2 PHASE	5	9.80e-01	-0.006620	9.95e-01
REACTOME CELL CELL COMMUNICATION	126	9.81e-01	-0.001240	9.95e-01
REACTOME CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT	19	9.81e-01	-0.003140	9.95e-01
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION	361	9.81e-01	-0.000717	9.95e-01
REACTOME SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA	52	9.82e-01	-0.001810	9.95e-01
REACTOME METABOLISM OF CARBOHYDRATES	279	9.82e-01	0.000779	9.95e-01
REACTOME RESPONSE OF MTB TO PHAGOCYTOSIS	22	9.85e-01	0.002390	9.96e-01
REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	24	9.86e-01	0.002130	9.96e-01
REACTOME DEFECTIVE EXT2 CAUSES EXOSTOSES 2	12	9.86e-01	-0.003020	9.96e-01
REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION	100	9.86e-01	0.001030	9.96e-01
REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	21	9.86e-01	-0.002210	9.96e-01
REACTOME TRANSCRIPTION OF THE HIV GENOME	66	9.86e-01	0.001220	9.96e-01
REACTOME CILIUM ASSEMBLY	190	9.87e-01	0.000709	9.96e-01
REACTOME SIGNALLING TO RAS	20	9.89e-01	-0.001840	9.97e-01
REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION	26	9.89e-01	-0.001570	9.97e-01
REACTOME METABOLISM OF STEROIDS	150	9.90e-01	0.000594	9.97e-01
REACTOME LONG TERM POTENTIATION	22	9.90e-01	-0.001500	9.97e-01
REACTOME COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM	21	9.91e-01	-0.001380	9.97e-01
REACTOME DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A	5	9.91e-01	-0.002820	9.97e-01
REACTOME VISUAL PHOTOTRANSDUCTION	93	9.92e-01	-0.000619	9.97e-01
REACTOME CHREBP ACTIVATES METABOLIC GENE EXPRESSION	8	9.93e-01	-0.001890	9.97e-01
REACTOME HYALURONAN UPTAKE AND DEGRADATION	12	9.93e-01	-0.001370	9.97e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS	15	9.94e-01	0.001180	9.97e-01
REACTOME INTERLEUKIN 6 SIGNALING	11	9.95e-01	-0.001200	9.97e-01
REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY	72	9.96e-01	-0.000312	9.98e-01
REACTOME PEROXISOMAL LIPID METABOLISM	28	9.97e-01	-0.000445	9.98e-01
REACTOME NGF STIMULATED TRANSCRIPTION	38	9.97e-01	-0.000302	9.98e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION	102	9.98e-01	-0.000176	9.98e-01

---

Detailed Gene set reports

REACTOME_RRNA_PROCESSING

REACTOME_RRNA_PROCESSING

	1148
set	REACTOME_RRNA_PROCESSING
setSize	192
pANOVA	1.79e-09
s.dist	0.252
p.adjustANOVA	2.94e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL10L	12167.0
RPS15A	11939.0
UTP15	11933.0
UTP3	11825.0
RPL7A	11625.0
RPL15	11453.0
RPL12	11427.0
RPS13	11420.0
RPL30	11333.0
RPP40	11246.0
PWP2	11243.0
RPS2	11169.0
UBA52	11156.0
RPL13A	10972.5
RPS12	10945.0
NOP56	10925.0
DIMT1	10852.0
BUD23	10819.0
EMG1	10792.0
RPL36AL	10700.5

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL10L	12167.0
RPS15A	11939.0
UTP15	11933.0
UTP3	11825.0
RPL7A	11625.0
RPL15	11453.0
RPL12	11427.0
RPS13	11420.0
RPL30	11333.0
RPP40	11246.0
PWP2	11243.0
RPS2	11169.0
UBA52	11156.0
RPL13A	10972.5
RPS12	10945.0
NOP56	10925.0
DIMT1	10852.0
BUD23	10819.0
EMG1	10792.0
RPL36AL	10700.5
EXOSC1	10538.0
TBL3	10490.0
ELAC2	10429.0
MTERF4	10387.0
RPL22L1	10372.0
RPS11	10361.0
RPL10A	10334.0
RPS21	10276.0
RPL37	10269.0
RPL28	10227.0
MRM1	10130.0
RPL9	10104.0
NOL12	10080.0
RPL23A	9993.0
WDR3	9954.0
ISG20L2	9901.0
RPS14	9890.0
RPL14	9804.0
RPS8	9803.0
RPLP1	9750.0
RPS6	9691.0
RPL27A	9530.0
RPL3	9494.0
EXOSC7	9477.0
RPS5	9380.0
RPS16	9206.0
UTP14C	9096.0
RPLP0	9015.0
WDR75	9012.0
RPL8	8995.0
RRP1	8969.0
RPS7	8958.0
UTP6	8920.0
FBL	8782.0
RPL26L1	8771.0
RPS10	8500.0
EXOSC6	8437.0
PNO1	8386.0
RPL21	8358.0
TSR1	8345.0
UTP25	8243.0
IMP3	8195.0
NOL6	8156.0
RCL1	8045.0
NIP7	7801.0
RPL29	7724.0
DIS3	7695.0
RPL13	7681.0
PDCD11	7619.0
RRP9	7590.0
RPS18	7574.0
RPS28	7553.0
FTSJ3	7473.0
EXOSC4	7332.0
EXOSC10	7261.0
RRP7A	7236.0
RPP38	7085.0
RPL18	6982.0
RPL24	6818.0
MPHOSPH10	6753.0
DDX49	6700.0
LTV1	6683.0
IMP4	6603.0
EBNA1BP2	6539.0
RPS26	6403.0
EXOSC3	6366.0
TEX10	6364.0
TSR3	6311.0
RPP25	6287.0
MPHOSPH6	6221.0
RPS29	6202.0
FAU	6182.0
NAT10	6125.0
DCAF13	6054.0
NOL9	5960.0
RPL36	5777.0
MRM2	5649.0
EXOSC8	5529.0
PES1	5518.0
RPSA	5509.0
RPP14	5266.0
RPL11	4720.0
RPS23	4694.0
WDR46	4598.0
NOP10	4398.0
RPS20	4325.0
WDR12	4190.0
PRORP	3897.0
BOP1	3793.0
DDX21	3790.0
RPS24	3750.0
UTP20	3652.0
RPS27A	3415.0
NOC4L	3359.0
RPL23	3223.0
RPS15	3030.0
RPS9	2957.0
TRMT10C	2933.0
RPS27	2734.0
UTP18	2714.0
HEATR1	2687.0
MTREX	2663.0
RPL35	2573.0
RPL26	2485.0
RPL37A	2197.0
TFB1M	2176.0
PELP1	2172.0
ERI1	2024.0
EXOSC9	1913.0
RPL18A	1454.0
NOP58	1391.0
RPS3	1293.0
TRMT112	1218.0
NOL11	1185.0
RPL7	1003.0
MRM3	927.0
RPL22	817.0
RRP36	684.0
EXOSC5	599.0
RPL38	447.0
UTP4	408.0
WDR36	190.0
NSUN4	60.0
RPL4	-477.0
RPP21	-488.0
RPS3A	-578.0
RPL6	-775.0
NHP2	-1080.0
BYSL	-1216.0
RPL5	-1407.0
RPL3L	-1681.0
UTP11	-1775.0
RPLP2	-1871.0
KRR1	-1890.0
DDX47	-1907.0
RIOK3	-1924.0
NOB1	-2078.0
RPS27L	-2461.0
RPL35A	-2635.0
WDR18	-2661.0
NOP14	-2745.0
RPL32	-2777.0
SNU13	-2895.0
CSNK1E	-3078.0
NCL	-3257.0
DHX37	-3279.0
EXOSC2	-3297.0
RPS19	-3548.0
DDX52	-3707.0
RPP30	-3898.0
GNL3	-3977.0
RPL27	-4089.0
BMS1	-4136.0
RPS25	-4512.0
RPL39L	-4522.0
RIOK1	-4844.0
RPL34	-5135.0
WDR43	-5566.0
XRN2	-5760.0
RIOK2	-5783.0
FCF1	-6110.0
THUMPD1	-6146.0
RPL19	-6199.0
GAR1	-6632.0
C1D	-6959.0
RPL41	-7598.0
RBM28	-7647.0
CSNK1D	-7665.0
RPL17	-7707.0
SENP3	-7761.0
RPL31	-8083.0
NOP2	-8275.0

---

REACTOME_SELENOAMINO_ACID_METABOLISM

REACTOME_SELENOAMINO_ACID_METABOLISM

	484
set	REACTOME_SELENOAMINO_ACID_METABOLISM
setSize	108
pANOVA	1.54e-08
s.dist	0.315
p.adjustANOVA	1.27e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
INMT	12234.0
RPL10L	12167.0
RPS15A	11939.0
RPL7A	11625.0
RPL15	11453.0
RPL12	11427.0
RPS13	11420.0
NNMT	11394.0
RPL30	11333.0
RPS2	11169.0
UBA52	11156.0
RPL13A	10972.5
RPS12	10945.0
RPL36AL	10700.5
RPL22L1	10372.0
RPS11	10361.0
RPL10A	10334.0
RPS21	10276.0
RPL37	10269.0
RPL28	10227.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
INMT	12234.0
RPL10L	12167.0
RPS15A	11939.0
RPL7A	11625.0
RPL15	11453.0
RPL12	11427.0
RPS13	11420.0
NNMT	11394.0
RPL30	11333.0
RPS2	11169.0
UBA52	11156.0
RPL13A	10972.5
RPS12	10945.0
RPL36AL	10700.5
RPL22L1	10372.0
RPS11	10361.0
RPL10A	10334.0
RPS21	10276.0
RPL37	10269.0
RPL28	10227.0
RPL9	10104.0
RPL23A	9993.0
RPS14	9890.0
MAT1A	9884.0
RPL14	9804.0
RPS8	9803.0
RPLP1	9750.0
RPS6	9691.0
RPL27A	9530.0
RPL3	9494.0
AIMP2	9481.0
KARS1	9433.0
RPS5	9380.0
RPS16	9206.0
RPLP0	9015.0
RPL8	8995.0
RPS7	8958.0
AIMP1	8892.0
RPL26L1	8771.0
HNMT	8556.0
RPS10	8500.0
RPL21	8358.0
RPL29	7724.0
RPL13	7681.0
RPS18	7574.0
RPS28	7553.0
CTH	7385.0
RARS1	7322.0
RPL18	6982.0
RPL24	6818.0
SECISBP2	6496.0
RPS26	6403.0
RPS29	6202.0
FAU	6182.0
EPRS1	6108.0
SCLY	5824.0
RPL36	5777.0
PSTK	5697.0
LARS1	5559.0
RPSA	5509.0
GSR	5373.0
IARS1	5308.0
RPL11	4720.0
RPS23	4694.0
RPS20	4325.0
MARS1	3885.0
RPS24	3750.0
SEPSECS	3656.0
RPS27A	3415.0
RPL23	3223.0
RPS15	3030.0
RPS9	2957.0
RPS27	2734.0
RPL35	2573.0
RPL26	2485.0
RPL37A	2197.0
PAPSS2	1946.0
RPL18A	1454.0
RPS3	1293.0
RPL7	1003.0
EEF1E1	999.0
RPL22	817.0
GNMT	490.0
RPL38	447.0
EEFSEC	-209.0
RPL4	-477.0
RPS3A	-578.0
RPL6	-775.0
SEPHS2	-1016.0
RPL5	-1407.0
RPL3L	-1681.0
RPLP2	-1871.0
PAPSS1	-1912.0
RPS27L	-2461.0
RPL35A	-2635.0
RPL32	-2777.0
RPS19	-3548.0
RPL27	-4089.0
RPS25	-4512.0
RPL39L	-4522.0
RPL34	-5135.0
AHCY	-5935.0
RPL19	-6199.0
TXNRD1	-6768.0
DARS1	-7413.0
RPL41	-7598.0
RPL17	-7707.0
RPL31	-8083.0

---

REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY

REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY

	1486
set	REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY
setSize	94
pANOVA	4.52e-08
s.dist	0.326
p.adjustANOVA	2.4e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL10L	12167.0
EIF2S2	12010.0
RPS15A	11939.0
RPL7A	11625.0
RPL15	11453.0
RPL12	11427.0
RPS13	11420.0
RPL30	11333.0
RPS2	11169.0
UBA52	11156.0
RPL13A	10972.5
RPS12	10945.0
RPL36AL	10700.5
RPL22L1	10372.0
RPS11	10361.0
RPL10A	10334.0
RPS21	10276.0
RPL37	10269.0
RPL28	10227.0
RPL9	10104.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL10L	12167.0
EIF2S2	12010.0
RPS15A	11939.0
RPL7A	11625.0
RPL15	11453.0
RPL12	11427.0
RPS13	11420.0
RPL30	11333.0
RPS2	11169.0
UBA52	11156.0
RPL13A	10972.5
RPS12	10945.0
RPL36AL	10700.5
RPL22L1	10372.0
RPS11	10361.0
RPL10A	10334.0
RPS21	10276.0
RPL37	10269.0
RPL28	10227.0
RPL9	10104.0
RPL23A	9993.0
RPS14	9890.0
RPL14	9804.0
RPS8	9803.0
RPLP1	9750.0
RPS6	9691.0
RPL27A	9530.0
RPL3	9494.0
RPS5	9380.0
RPS16	9206.0
ASNS	9163.0
RPLP0	9015.0
RPL8	8995.0
RPS7	8958.0
GCN1	8902.0
ATF3	8882.0
RPL26L1	8771.0
RPS10	8500.0
RPL21	8358.0
RPL29	7724.0
RPL13	7681.0
RPS18	7574.0
RPS28	7553.0
TRIB3	7010.0
RPL18	6982.0
RPL24	6818.0
RPS26	6403.0
RPS29	6202.0
FAU	6182.0
RPL36	5777.0
RPSA	5509.0
IMPACT	5223.0
ATF4	4881.0
RPL11	4720.0
RPS23	4694.0
EIF2S1	4512.0
RPS20	4325.0
RPS24	3750.0
RPS27A	3415.0
ATF2	3351.0
RPL23	3223.0
RPS15	3030.0
RPS9	2957.0
RPS27	2734.0
RPL35	2573.0
RPL26	2485.0
RPL37A	2197.0
RPL18A	1454.0
RPS3	1293.0
RPL7	1003.0
RPL22	817.0
CEBPB	710.0
RPL38	447.0
EIF2AK4	-91.0
RPL4	-477.0
RPS3A	-578.0
RPL6	-775.0
RPL5	-1407.0
RPL3L	-1681.0
RPLP2	-1871.0
CEBPG	-2016.0
RPS27L	-2461.0
RPL35A	-2635.0
RPL32	-2777.0
RPS19	-3548.0
RPL27	-4089.0
RPS25	-4512.0
RPL39L	-4522.0
RPL34	-5135.0
DDIT3	-5823.0
RPL19	-6199.0
RPL41	-7598.0
RPL17	-7707.0
RPL31	-8083.0

---

REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION

REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION

	151
set	REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION
setSize	87
pANOVA	6.7e-08
s.dist	0.335
p.adjustANOVA	2.4e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL10L	12167.0
RPS15A	11939.0
RPL7A	11625.0
RPL15	11453.0
RPL12	11427.0
RPS13	11420.0
RPL30	11333.0
EEF1B2	11290.0
RPS2	11169.0
UBA52	11156.0
RPL13A	10972.5
RPS12	10945.0
RPL36AL	10700.5
RPL22L1	10372.0
RPS11	10361.0
RPL10A	10334.0
RPS21	10276.0
RPL37	10269.0
RPL28	10227.0
RPL9	10104.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL10L	12167.0
RPS15A	11939.0
RPL7A	11625.0
RPL15	11453.0
RPL12	11427.0
RPS13	11420.0
RPL30	11333.0
EEF1B2	11290.0
RPS2	11169.0
UBA52	11156.0
RPL13A	10972.5
RPS12	10945.0
RPL36AL	10700.5
RPL22L1	10372.0
RPS11	10361.0
RPL10A	10334.0
RPS21	10276.0
RPL37	10269.0
RPL28	10227.0
RPL9	10104.0
RPL23A	9993.0
EEF1A1	9945.0
RPS14	9890.0
RPL14	9804.0
RPS8	9803.0
RPLP1	9750.0
EEF2	9712.0
RPS6	9691.0
RPL27A	9530.0
RPL3	9494.0
RPS5	9380.0
RPS16	9206.0
RPLP0	9015.0
RPL8	8995.0
RPS7	8958.0
RPL26L1	8771.0
RPS10	8500.0
RPL21	8358.0
RPL29	7724.0
RPL13	7681.0
RPS18	7574.0
RPS28	7553.0
RPL18	6982.0
RPL24	6818.0
RPS26	6403.0
RPS29	6202.0
FAU	6182.0
RPL36	5777.0
RPSA	5509.0
RPL11	4720.0
RPS23	4694.0
RPS20	4325.0
EEF1D	3909.0
RPS24	3750.0
RPS27A	3415.0
RPL23	3223.0
RPS15	3030.0
RPS9	2957.0
RPS27	2734.0
RPL35	2573.0
RPL26	2485.0
RPL37A	2197.0
RPL18A	1454.0
RPS3	1293.0
RPL7	1003.0
RPL22	817.0
RPL38	447.0
RPL4	-477.0
EEF1G	-486.0
RPS3A	-578.0
RPL6	-775.0
RPL5	-1407.0
RPL3L	-1681.0
RPLP2	-1871.0
RPS27L	-2461.0
RPL35A	-2635.0
RPL32	-2777.0
RPS19	-3548.0
RPL27	-4089.0
EEF1A2	-4314.0
RPS25	-4512.0
RPL39L	-4522.0
RPL34	-5135.0
RPL19	-6199.0
RPL41	-7598.0
RPL17	-7707.0
RPL31	-8083.0

---

REACTOME_TRANSLATION

REACTOME_TRANSLATION

	1152
set	REACTOME_TRANSLATION
setSize	278
pANOVA	7.3e-08
s.dist	0.188
p.adjustANOVA	2.4e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL10L	12167.0
MRPL45	12063.0
EIF2S2	12010.0
RPS15A	11939.0
MRPL21	11702.0
RPL7A	11625.0
EIF3F	11563.0
RPL15	11453.0
RPL12	11427.0
RPS13	11420.0
RPL30	11333.0
EEF1B2	11290.0
RPS2	11169.0
UBA52	11156.0
RPL13A	10972.5
RPS12	10945.0
FARSA	10908.0
EIF2B4	10907.0
CHCHD1	10864.0
MRPL47	10831.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL10L	12167.0
MRPL45	12063.0
EIF2S2	12010.0
RPS15A	11939.0
MRPL21	11702.0
RPL7A	11625.0
EIF3F	11563.0
RPL15	11453.0
RPL12	11427.0
RPS13	11420.0
RPL30	11333.0
EEF1B2	11290.0
RPS2	11169.0
UBA52	11156.0
RPL13A	10972.5
RPS12	10945.0
FARSA	10908.0
EIF2B4	10907.0
CHCHD1	10864.0
MRPL47	10831.0
RPN2	10781.0
SEC11C	10742.0
RPL36AL	10700.5
MRPL24	10583.0
TUFM	10496.0
DARS2	10480.0
MTRF1L	10436.0
SEC61G	10401.0
RPL22L1	10372.0
RPS11	10361.0
MRPL58	10358.0
RPL10A	10334.0
MRPS12	10277.0
RPS21	10276.0
RPL37	10269.0
MRPL40	10249.0
MRPL19	10230.0
RPL28	10227.0
RPL9	10104.0
RPL23A	9993.0
EEF1A1	9945.0
MRPL39	9909.0
RPS14	9890.0
SARS2	9817.0
RPL14	9804.0
RPS8	9803.0
RPLP1	9750.0
EEF2	9712.0
RPS6	9691.0
MTIF3	9559.0
RPL27A	9530.0
MRPS28	9520.0
RPL3	9494.0
AIMP2	9481.0
KARS1	9433.0
EIF3G	9405.0
AARS2	9401.0
RPS5	9380.0
MRPL18	9323.0
RPS16	9206.0
MRPS18A	9176.0
RPLP0	9015.0
MRPS18C	9010.0
RPL8	8995.0
SPCS2	8962.0
RPS7	8958.0
AIMP1	8892.0
RPL26L1	8771.0
MRPL36	8745.0
MRPL13	8716.0
RPS10	8500.0
EIF5B	8417.0
YARS2	8376.0
RPL21	8358.0
TARS1	8086.0
ETF1	8051.0
SRPRB	7990.0
MRPL50	7788.0
RPL29	7724.0
MRPS25	7683.0
RPL13	7681.0
MRPL9	7586.0
EIF4A2	7575.0
RPS18	7574.0
RPS28	7553.0
MRPL52	7522.0
EIF2B3	7514.0
PPA2	7453.0
MRRF	7442.0
RARS1	7322.0
EIF4B	7164.0
RPL18	6982.0
GFM2	6918.0
MRPL41	6904.0
MRPL49	6819.0
RPL24	6818.0
EARS2	6740.0
PTCD3	6666.0
SRP72	6585.0
WARS2	6523.0
RPS26	6403.0
MRPL46	6267.0
RPS29	6202.0
MRPS15	6184.0
FAU	6182.0
MRPS14	6169.0
EPRS1	6108.0
MRPS27	6079.0
MRPS9	5982.0
MRPL51	5828.0
RPL36	5777.0
MRPS30	5685.0
NARS1	5603.0
LARS1	5559.0
RPSA	5509.0
MRPL12	5485.0
SEC61B	5478.0
MRPL30	5449.0
MRPS2	5398.0
MRPS11	5376.0
SPCS3	5343.0
MRPL57	5332.0
IARS1	5308.0
MRPS16	5166.0
MRPL55	5129.0
RPN1	5072.0
MRPL42	4985.0
SRP68	4909.0
RPL11	4720.0
RPS23	4694.0
TSFM	4577.0
SPCS1	4526.0
EIF2S1	4512.0
MARS2	4470.0
RPS20	4325.0
SEC61A2	4301.0
PABPC1	4184.0
MRPS18B	4133.0
MRPL15	4096.0
MRPL22	4073.0
EIF3B	3972.0
EIF5	3944.0
EEF1D	3909.0
SSR3	3896.0
MARS1	3885.0
RPS24	3750.0
MRPL43	3705.0
RARS2	3458.0
RPS27A	3415.0
MRPS34	3402.0
AARS1	3360.0
RPL23	3223.0
EIF2B5	3186.0
MRPS5	3134.0
MRPS10	3112.0
MRPS33	3100.0
RPS15	3030.0
RPS9	2957.0
SEC11A	2935.0
EIF4E	2774.0
MRPL27	2770.0
RPS27	2734.0
APEH	2608.0
RPL35	2573.0
RPL26	2485.0
MRPS24	2421.0
YARS1	2379.0
MRPL16	2360.0
MRPL2	2274.0
MRPL28	2252.0
RPL37A	2197.0
SSR1	2048.0
MRPL1	1977.0
EIF3H	1949.0
MRPL14	1828.0
SRPRA	1705.0
MRPL37	1653.0
MRPL48	1615.0
WARS1	1482.0
HARS2	1457.0
RPL18A	1454.0
RPS3	1293.0
TRMT112	1218.0
LARS2	1009.0
RPL7	1003.0
EEF1E1	999.0
RPL22	817.0
MRPL32	639.0
MRPL4	615.0
OXA1L	560.0
MTFMT	518.0
MRPS22	487.0
FARS2	466.0
RPL38	447.0
EIF3I	438.0
PARS2	375.0
SRP19	373.0
MRPL53	240.0
MRPS17	229.0
MRPS26	-204.0
IARS2	-259.0
MRPL54	-278.0
DDOST	-293.0
MRPL17	-408.0
RPL4	-477.0
EEF1G	-486.0
MRPS21	-574.0
RPS3A	-578.0
MRPS7	-583.0
MRPL10	-620.0
RPL6	-775.0
SEC61A1	-843.0
DAP3	-900.0
FARSB	-940.0
PPA1	-1245.0
RPL5	-1407.0
RPL3L	-1681.0
EIF2B2	-1724.0
EIF3J	-1856.0
RPLP2	-1871.0
SRP14	-1984.0
MRPS6	-2360.0
RPS27L	-2461.0
EIF3A	-2535.0
AURKAIP1	-2537.0
RPL35A	-2635.0
TARS2	-2637.0
RPL32	-2777.0
EIF3M	-2840.0
EIF4A1	-2862.0
MRPL23	-2917.0
EIF4H	-3503.0
RPS19	-3548.0
ERAL1	-3678.0
MRPL38	-3832.0
CARS1	-3870.0
HARS1	-3872.0
MRPS31	-3892.0
EIF3E	-3919.0
MRPL3	-4088.0
RPL27	-4089.0
MRPS35	-4220.0
EIF3D	-4233.0
EEF1A2	-4314.0
RPS25	-4512.0
RPL39L	-4522.0
GARS1	-4552.0
SSR2	-4598.0
RPL34	-5135.0
EIF3K	-5313.0
MRPL33	-5600.0
SRP9	-5749.0
EIF2B1	-5773.0
SRP54	-5940.0
CARS2	-5944.0
MRPS23	-6078.0
RPL19	-6199.0
MTIF2	-6279.0
MRPL11	-6289.0
MRPL20	-6320.0
VARS2	-6445.0
EIF4G1	-6670.0
MRPL34	-6757.0
MRPL35	-6885.0
GSPT1	-6923.0
EIF3L	-7058.0
MRPL44	-7214.0
NARS2	-7274.0
EIF4EBP1	-7305.0
GADD45GIP1	-7407.0
DARS1	-7413.0
VARS1	-7495.0
RPL41	-7598.0
RPL17	-7707.0
GFM1	-7759.0
RPL31	-8083.0
TRAM1	-8793.0
N6AMT1	-9104.0

---

REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE

REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE

	271
set	REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE
setSize	105
pANOVA	3.21e-07
s.dist	0.289
p.adjustANOVA	8.79e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL10L	12167.0
RPS15A	11939.0
RPL7A	11625.0
RPL15	11453.0
RPL12	11427.0
RPS13	11420.0
RPL30	11333.0
RPS2	11169.0
UBA52	11156.0
RPL13A	10972.5
RPS12	10945.0
RPN2	10781.0
SEC11C	10742.0
RPL36AL	10700.5
SEC61G	10401.0
RPL22L1	10372.0
RPS11	10361.0
RPL10A	10334.0
RPS21	10276.0
RPL37	10269.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL10L	12167.0
RPS15A	11939.0
RPL7A	11625.0
RPL15	11453.0
RPL12	11427.0
RPS13	11420.0
RPL30	11333.0
RPS2	11169.0
UBA52	11156.0
RPL13A	10972.5
RPS12	10945.0
RPN2	10781.0
SEC11C	10742.0
RPL36AL	10700.5
SEC61G	10401.0
RPL22L1	10372.0
RPS11	10361.0
RPL10A	10334.0
RPS21	10276.0
RPL37	10269.0
RPL28	10227.0
RPL9	10104.0
RPL23A	9993.0
RPS14	9890.0
RPL14	9804.0
RPS8	9803.0
RPLP1	9750.0
RPS6	9691.0
RPL27A	9530.0
RPL3	9494.0
RPS5	9380.0
RPS16	9206.0
RPLP0	9015.0
RPL8	8995.0
SPCS2	8962.0
RPS7	8958.0
RPL26L1	8771.0
RPS10	8500.0
RPL21	8358.0
SRPRB	7990.0
RPL29	7724.0
RPL13	7681.0
RPS18	7574.0
RPS28	7553.0
RPL18	6982.0
RPL24	6818.0
SRP72	6585.0
RPS26	6403.0
RPS29	6202.0
FAU	6182.0
RPL36	5777.0
RPSA	5509.0
SEC61B	5478.0
SPCS3	5343.0
RPN1	5072.0
SRP68	4909.0
RPL11	4720.0
RPS23	4694.0
SPCS1	4526.0
RPS20	4325.0
SEC61A2	4301.0
SSR3	3896.0
RPS24	3750.0
RPS27A	3415.0
RPL23	3223.0
RPS15	3030.0
RPS9	2957.0
SEC11A	2935.0
RPS27	2734.0
RPL35	2573.0
RPL26	2485.0
RPL37A	2197.0
SSR1	2048.0
SRPRA	1705.0
RPL18A	1454.0
RPS3	1293.0
RPL7	1003.0
RPL22	817.0
RPL38	447.0
SRP19	373.0
DDOST	-293.0
RPL4	-477.0
RPS3A	-578.0
RPL6	-775.0
SEC61A1	-843.0
RPL5	-1407.0
RPL3L	-1681.0
RPLP2	-1871.0
SRP14	-1984.0
RPS27L	-2461.0
RPL35A	-2635.0
RPL32	-2777.0
RPS19	-3548.0
RPL27	-4089.0
RPS25	-4512.0
RPL39L	-4522.0
SSR2	-4598.0
RPL34	-5135.0
SRP9	-5749.0
SRP54	-5940.0
RPL19	-6199.0
RPL41	-7598.0
RPL17	-7707.0
RPL31	-8083.0
TRAM1	-8793.0

---

REACTOME_CELLULAR_RESPONSE_TO_STARVATION

REACTOME_CELLULAR_RESPONSE_TO_STARVATION

	1582
set	REACTOME_CELLULAR_RESPONSE_TO_STARVATION
setSize	147
pANOVA	6.25e-07
s.dist	0.238
p.adjustANOVA	0.000146

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL10L	12167.0
EIF2S2	12010.0
RPS15A	11939.0
RPL7A	11625.0
RPL15	11453.0
RPL12	11427.0
RPS13	11420.0
RPL30	11333.0
RPS2	11169.0
UBA52	11156.0
RPL13A	10972.5
RPS12	10945.0
RPL36AL	10700.5
RRAGA	10694.0
RPL22L1	10372.0
RPS11	10361.0
RPL10A	10334.0
RPS21	10276.0
RPL37	10269.0
LAMTOR5	10238.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL10L	12167.0
EIF2S2	12010.0
RPS15A	11939.0
RPL7A	11625.0
RPL15	11453.0
RPL12	11427.0
RPS13	11420.0
RPL30	11333.0
RPS2	11169.0
UBA52	11156.0
RPL13A	10972.5
RPS12	10945.0
RPL36AL	10700.5
RRAGA	10694.0
RPL22L1	10372.0
RPS11	10361.0
RPL10A	10334.0
RPS21	10276.0
RPL37	10269.0
LAMTOR5	10238.0
RPL28	10227.0
RPL9	10104.0
RPL23A	9993.0
RPS14	9890.0
RPL14	9804.0
RPS8	9803.0
RPLP1	9750.0
RPS6	9691.0
RPL27A	9530.0
RPL3	9494.0
RPS5	9380.0
ATP6V1F	9327.0
RPS16	9206.0
ASNS	9163.0
RPLP0	9015.0
LAMTOR1	9002.0
RPL8	8995.0
RPS7	8958.0
GCN1	8902.0
ATF3	8882.0
NPRL2	8857.0
RPL26L1	8771.0
ATP6V0B	8503.0
RPS10	8500.0
RPL21	8358.0
KICS2	8216.0
MIOS	7957.0
ATP6V0D2	7850.0
RPL29	7724.0
RPL13	7681.0
WDR24	7675.0
RPS18	7574.0
RPS28	7553.0
ITFG2	7520.0
RRAGD	7319.0
TRIB3	7010.0
RPL18	6982.0
ATP6V1B1	6973.0
ATP6V0D1	6895.0
RPL24	6818.0
RPS26	6403.0
RPS29	6202.0
FAU	6182.0
MTOR	6074.0
SZT2	5844.0
RPL36	5777.0
RPSA	5509.0
IMPACT	5223.0
KPTN	5046.0
ATP6V1C2	4888.0
ATF4	4881.0
SLC38A9	4798.0
ATP6V1E2	4761.0
RPL11	4720.0
ATP6V1D	4719.0
RPS23	4694.0
EIF2S1	4512.0
RPS20	4325.0
LAMTOR3	4157.0
SEC13	3809.0
ATP6V1G1	3770.0
RPS24	3750.0
ATP6V1A	3738.0
ATP6V1E1	3576.0
RPS27A	3415.0
ATF2	3351.0
RPL23	3223.0
ATP6V1G2	3127.0
RPS15	3030.0
RPS9	2957.0
RPS27	2734.0
RPL35	2573.0
RPL26	2485.0
TCIRG1	2255.0
RPL37A	2197.0
SEH1L	1872.0
ATP6V1G3	1495.0
RPL18A	1454.0
RPS3	1293.0
LAMTOR4	1113.0
RPL7	1003.0
NPRL3	865.0
RPL22	817.0
CEBPB	710.0
FNIP1	537.0
ATP6V0E1	483.0
RPL38	447.0
EIF2AK4	-91.0
BMT2	-99.0
CASTOR1	-277.0
RPL4	-477.0
RPS3A	-578.0
RPTOR	-731.0
RPL6	-775.0
SH3BP4	-953.0
RPL5	-1407.0
FNIP2	-1477.0
RPL3L	-1681.0
FLCN	-1761.0
RPLP2	-1871.0
CEBPG	-2016.0
ATP6V1B2	-2062.0
LAMTOR2	-2400.0
DEPDC5	-2454.0
RPS27L	-2461.0
WDR59	-2576.0
RPL35A	-2635.0
RPL32	-2777.0
SESN1	-2933.0
RPS19	-3548.0
ATP6V1C1	-4076.0
RPL27	-4089.0
RPS25	-4512.0
RPL39L	-4522.0
SESN2	-4734.0
ATP6V0C	-4801.0
ATP6V1H	-5003.0
RPL34	-5135.0
DDIT3	-5823.0
RRAGC	-6076.0
RPL19	-6199.0
RHEB	-6717.0
MLST8	-6792.0
ATP6V0E2	-7468.0
RPL41	-7598.0
RPL17	-7707.0
RPL31	-8083.0

---

REACTOME_EUKARYOTIC_TRANSLATION_INITIATION

REACTOME_EUKARYOTIC_TRANSLATION_INITIATION

	1149
set	REACTOME_EUKARYOTIC_TRANSLATION_INITIATION
setSize	110
pANOVA	5.96e-06
s.dist	0.25
p.adjustANOVA	0.00122

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL10L	12167.0
EIF2S2	12010.0
RPS15A	11939.0
RPL7A	11625.0
EIF3F	11563.0
RPL15	11453.0
RPL12	11427.0
RPS13	11420.0
RPL30	11333.0
RPS2	11169.0
UBA52	11156.0
RPL13A	10972.5
RPS12	10945.0
EIF2B4	10907.0
RPL36AL	10700.5
RPL22L1	10372.0
RPS11	10361.0
RPL10A	10334.0
RPS21	10276.0
RPL37	10269.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL10L	12167.0
EIF2S2	12010.0
RPS15A	11939.0
RPL7A	11625.0
EIF3F	11563.0
RPL15	11453.0
RPL12	11427.0
RPS13	11420.0
RPL30	11333.0
RPS2	11169.0
UBA52	11156.0
RPL13A	10972.5
RPS12	10945.0
EIF2B4	10907.0
RPL36AL	10700.5
RPL22L1	10372.0
RPS11	10361.0
RPL10A	10334.0
RPS21	10276.0
RPL37	10269.0
RPL28	10227.0
RPL9	10104.0
RPL23A	9993.0
RPS14	9890.0
RPL14	9804.0
RPS8	9803.0
RPLP1	9750.0
RPS6	9691.0
RPL27A	9530.0
RPL3	9494.0
EIF3G	9405.0
RPS5	9380.0
RPS16	9206.0
RPLP0	9015.0
RPL8	8995.0
RPS7	8958.0
RPL26L1	8771.0
RPS10	8500.0
EIF5B	8417.0
RPL21	8358.0
RPL29	7724.0
RPL13	7681.0
EIF4A2	7575.0
RPS18	7574.0
RPS28	7553.0
EIF2B3	7514.0
EIF4B	7164.0
RPL18	6982.0
RPL24	6818.0
RPS26	6403.0
RPS29	6202.0
FAU	6182.0
RPL36	5777.0
RPSA	5509.0
RPL11	4720.0
RPS23	4694.0
EIF2S1	4512.0
RPS20	4325.0
PABPC1	4184.0
EIF3B	3972.0
EIF5	3944.0
RPS24	3750.0
RPS27A	3415.0
RPL23	3223.0
EIF2B5	3186.0
RPS15	3030.0
RPS9	2957.0
EIF4E	2774.0
RPS27	2734.0
RPL35	2573.0
RPL26	2485.0
RPL37A	2197.0
EIF3H	1949.0
RPL18A	1454.0
RPS3	1293.0
RPL7	1003.0
RPL22	817.0
RPL38	447.0
EIF3I	438.0
RPL4	-477.0
RPS3A	-578.0
RPL6	-775.0
RPL5	-1407.0
RPL3L	-1681.0
EIF2B2	-1724.0
EIF3J	-1856.0
RPLP2	-1871.0
RPS27L	-2461.0
EIF3A	-2535.0
RPL35A	-2635.0
RPL32	-2777.0
EIF3M	-2840.0
EIF4A1	-2862.0
EIF4H	-3503.0
RPS19	-3548.0
EIF3E	-3919.0
RPL27	-4089.0
EIF3D	-4233.0
RPS25	-4512.0
RPL39L	-4522.0
RPL34	-5135.0
EIF3K	-5313.0
EIF2B1	-5773.0
RPL19	-6199.0
EIF4G1	-6670.0
EIF3L	-7058.0
EIF4EBP1	-7305.0
RPL41	-7598.0
RPL17	-7707.0
RPL31	-8083.0

---

REACTOME_INFLUENZA_INFECTION

REACTOME_INFLUENZA_INFECTION

	228
set	REACTOME_INFLUENZA_INFECTION
setSize	149
pANOVA	8.83e-06
s.dist	0.211
p.adjustANOVA	0.00161

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL10L	12167.0
RPS15A	11939.0
RPL7A	11625.0
RPL15	11453.0
NUP88	11439.0
RPL12	11427.0
RPS13	11420.0
RPL30	11333.0
RPS2	11169.0
UBA52	11156.0
RPL13A	10972.5
RPS12	10945.0
POM121C	10915.0
RPL36AL	10700.5
RPL22L1	10372.0
RPS11	10361.0
RPL10A	10334.0
RPS21	10276.0
RPL37	10269.0
RPL28	10227.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL10L	12167.0
RPS15A	11939.0
RPL7A	11625.0
RPL15	11453.0
NUP88	11439.0
RPL12	11427.0
RPS13	11420.0
RPL30	11333.0
RPS2	11169.0
UBA52	11156.0
RPL13A	10972.5
RPS12	10945.0
POM121C	10915.0
RPL36AL	10700.5
RPL22L1	10372.0
RPS11	10361.0
RPL10A	10334.0
RPS21	10276.0
RPL37	10269.0
RPL28	10227.0
RPL9	10104.0
RPL23A	9993.0
RPS14	9890.0
RPL14	9804.0
RPS8	9803.0
NUP42	9786.0
RPLP1	9750.0
RPS6	9691.0
RPL27A	9530.0
RPL3	9494.0
RPS5	9380.0
RPS16	9206.0
RPLP0	9015.0
RPL8	8995.0
RPS7	8958.0
KPNA2	8879.0
HSP90AA1	8781.0
RPL26L1	8771.0
NUP43	8536.0
RPS10	8500.0
NUP62	8463.0
NUP107	8380.0
RPL21	8358.0
NUP133	8148.0
POLR2B	7880.0
RPL29	7724.0
RPL13	7681.0
GTF2F1	7678.0
RPS18	7574.0
RPS28	7553.0
NUP155	7250.0
KPNA3	7119.0
RPL18	6982.0
TPR	6866.0
IPO5	6857.0
RPL24	6818.0
POLR2F	6801.0
KPNA4	6545.0
RPS26	6403.0
RPS29	6202.0
FAU	6182.0
KPNB1	6090.0
PARP1	5812.0
RPL36	5777.0
CANX	5676.0
RPSA	5509.0
NUP37	5379.0
NUP93	5225.0
NUP188	5176.0
NUP160	4948.0
TGFB1	4753.0
RPL11	4720.0
RPS23	4694.0
POLR2D	4651.0
CALR	4428.0
NUP35	4415.0
EIF2AK2	4373.0
RPS20	4325.0
KPNA7	4285.0
NUP205	3947.0
POLR2A	3845.0
SEC13	3809.0
POLR2G	3785.0
RPS24	3750.0
RANBP2	3650.0
RPS27A	3415.0
ISG15	3326.0
RPL23	3223.0
NUP54	3207.0
RPS15	3030.0
RPS9	2957.0
POLR2H	2882.0
RPS27	2734.0
RPL35	2573.0
NUP98	2548.0
RPL26	2485.0
RPL37A	2197.0
SEH1L	1872.0
HSPA1A	1651.0
RPL18A	1454.0
RPS3	1293.0
RPL7	1003.0
NDC1	964.0
RPL22	817.0
DNAJC3	581.0
RPL38	447.0
POLR2I	261.0
POLR2L	160.0
RPL4	-477.0
XPO1	-547.0
RPS3A	-578.0
KPNA5	-633.0
RPL6	-775.0
CLTC	-809.0
RPL5	-1407.0
RPL3L	-1681.0
RPLP2	-1871.0
CLTA	-1993.0
POLR2K	-2038.0
RPS27L	-2461.0
AAAS	-2517.0
RPL35A	-2635.0
RPL32	-2777.0
KPNA1	-3049.0
RPS19	-3548.0
NUP153	-3940.0
NUP210	-3969.0
NUP50	-3978.0
POLR2C	-4056.0
RPL27	-4089.0
RPS25	-4512.0
RPL39L	-4522.0
GTF2F2	-4815.0
GRSF1	-4873.0
RPL34	-5135.0
PABPN1	-5187.0
NUP214	-5218.0
CPSF4	-5354.0
POLR2E	-5528.0
NUP58	-5770.0
RAN	-5878.0
RPL19	-6199.0
RAE1	-6991.0
NUP85	-7391.0
RPL41	-7598.0
RPL17	-7707.0
POLR2J	-8074.0
RPL31	-8083.0
POM121	-8428.0

---

REACTOME_NONSENSE_MEDIATED_DECAY_NMD

REACTOME_NONSENSE_MEDIATED_DECAY_NMD

	1443
set	REACTOME_NONSENSE_MEDIATED_DECAY_NMD
setSize	107
pANOVA	1.83e-05
s.dist	0.24
p.adjustANOVA	0.003

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL10L	12167.0
RPS15A	11939.0
RPL7A	11625.0
RPL15	11453.0
RPL12	11427.0
RPS13	11420.0
RPL30	11333.0
RPS2	11169.0
UBA52	11156.0
PNRC2	11136.0
RPL13A	10972.5
RPS12	10945.0
RPL36AL	10700.5
RPL22L1	10372.0
RPS11	10361.0
RPL10A	10334.0
RPS21	10276.0
RPL37	10269.0
RPL28	10227.0
RPL9	10104.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL10L	12167.0
RPS15A	11939.0
RPL7A	11625.0
RPL15	11453.0
RPL12	11427.0
RPS13	11420.0
RPL30	11333.0
RPS2	11169.0
UBA52	11156.0
PNRC2	11136.0
RPL13A	10972.5
RPS12	10945.0
RPL36AL	10700.5
RPL22L1	10372.0
RPS11	10361.0
RPL10A	10334.0
RPS21	10276.0
RPL37	10269.0
RPL28	10227.0
RPL9	10104.0
RPL23A	9993.0
RPS14	9890.0
RPL14	9804.0
RPS8	9803.0
RPLP1	9750.0
RPS6	9691.0
RPL27A	9530.0
RPL3	9494.0
RPS5	9380.0
RPS16	9206.0
PPP2R1A	9045.0
RPLP0	9015.0
RPL8	8995.0
RPS7	8958.0
RPL26L1	8771.0
RPS10	8500.0
RPL21	8358.0
ETF1	8051.0
RPL29	7724.0
RPL13	7681.0
SMG9	7655.0
RPS18	7574.0
RPS28	7553.0
EIF4A3	7076.0
RPL18	6982.0
RPL24	6818.0
RPS26	6403.0
RPS29	6202.0
FAU	6182.0
NCBP2	6104.0
RNPS1	6016.0
RPL36	5777.0
RBM8A	5688.0
RPSA	5509.0
SMG1	5144.0
RPL11	4720.0
RPS23	4694.0
MAGOHB	4342.0
RPS20	4325.0
PABPC1	4184.0
RPS24	3750.0
RPS27A	3415.0
RPL23	3223.0
RPS15	3030.0
RPS9	2957.0
RPS27	2734.0
RPL35	2573.0
RPL26	2485.0
RPL37A	2197.0
RPL18A	1454.0
RPS3	1293.0
RPL7	1003.0
RPL22	817.0
RPL38	447.0
SMG7	436.0
DCP1A	136.0
SMG8	-184.0
RPL4	-477.0
RPS3A	-578.0
RPL6	-775.0
MAGOH	-1401.0
RPL5	-1407.0
RPL3L	-1681.0
RPLP2	-1871.0
CASC3	-2269.0
SMG5	-2432.0
RPS27L	-2461.0
PPP2CA	-2522.0
RPL35A	-2635.0
RPL32	-2777.0
UPF2	-3217.0
RPS19	-3548.0
NCBP1	-4046.0
RPL27	-4089.0
RPS25	-4512.0
RPL39L	-4522.0
RPL34	-5135.0
PPP2R2A	-5772.0
SMG6	-5936.0
RPL19	-6199.0
UPF3A	-6399.0
EIF4G1	-6670.0
GSPT1	-6923.0
UPF1	-7534.0
RPL41	-7598.0
RPL17	-7707.0
RPL31	-8083.0

---

REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY

REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY

	1591
set	REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY
setSize	33
pANOVA	2.52e-05
s.dist	0.424
p.adjustANOVA	0.00376

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS15A	11939
RPS13	11420
RPS2	11169
RPS12	10945
RPS11	10361
RPS21	10276
EEF1A1	9945
RPS14	9890
RPS8	9803
RPS6	9691
RPS5	9380
RPS16	9206
RPS7	8958
RPS10	8500
RPS18	7574
RPS28	7553
RPS26	6403
RPS29	6202
FAU	6182
RPSA	5509

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS15A	11939
RPS13	11420
RPS2	11169
RPS12	10945
RPS11	10361
RPS21	10276
EEF1A1	9945
RPS14	9890
RPS8	9803
RPS6	9691
RPS5	9380
RPS16	9206
RPS7	8958
RPS10	8500
RPS18	7574
RPS28	7553
RPS26	6403
RPS29	6202
FAU	6182
RPSA	5509
RPS23	4694
RPS20	4325
HNRNPA1	3771
RPS24	3750
RPS27A	3415
RPS15	3030
RPS9	2957
RPS27	2734
RPS3	1293
RPS3A	-578
RPS27L	-2461
RPS19	-3548
RPS25	-4512

---

REACTOME_FGFR1_MUTANT_RECEPTOR_ACTIVATION

REACTOME_FGFR1_MUTANT_RECEPTOR_ACTIVATION

	287
set	REACTOME_FGFR1_MUTANT_RECEPTOR_ACTIVATION
setSize	31
pANOVA	2.97e-05
s.dist	-0.433
p.adjustANOVA	0.00406

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FGF17	-8899
FGF2	-8712
STAT3	-8571
FGF8	-8519
FGF23	-8241
CNTRL	-8135
STAT5B	-7052
PIK3R1	-6466
BCR	-6189
FGF5	-6062
GRB2	-5790
MYO18A	-5665
TRIM24	-5643
CUX1	-5038
FGFR1OP2	-4706
STAT5A	-4603
LRRFIP1	-4565
FGF20	-2754
FGF4	-2221
FGF9	-2184

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FGF17	-8899
FGF2	-8712
STAT3	-8571
FGF8	-8519
FGF23	-8241
CNTRL	-8135
STAT5B	-7052
PIK3R1	-6466
BCR	-6189
FGF5	-6062
GRB2	-5790
MYO18A	-5665
TRIM24	-5643
CUX1	-5038
FGFR1OP2	-4706
STAT5A	-4603
LRRFIP1	-4565
FGF20	-2754
FGF4	-2221
FGF9	-2184
CEP43	-1989
BAG4	-1640
ERLIN2	-1516
ZMYM2	-1173
PIK3CA	265
CPSF6	1521
STAT1	2001
GAB2	2954
FGF6	4751
FGF1	5299
FGFR1	5333

---

REACTOME_SIGNALING_BY_FGFR1_IN_DISEASE

REACTOME_SIGNALING_BY_FGFR1_IN_DISEASE

	962
set	REACTOME_SIGNALING_BY_FGFR1_IN_DISEASE
setSize	38
pANOVA	5.67e-05
s.dist	-0.377
p.adjustANOVA	0.00716

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FGF17	-8899
FGF2	-8712
STAT3	-8571
FGF8	-8519
FGF23	-8241
CNTRL	-8135
STAT5B	-7052
FRS2	-7024
PIK3R1	-6466
BCR	-6189
FGF5	-6062
GRB2	-5790
MYO18A	-5665
TRIM24	-5643
NRAS	-5634
CUX1	-5038
FGFR1OP2	-4706
STAT5A	-4603
LRRFIP1	-4565
GAB1	-2761

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FGF17	-8899
FGF2	-8712
STAT3	-8571
FGF8	-8519
FGF23	-8241
CNTRL	-8135
STAT5B	-7052
FRS2	-7024
PIK3R1	-6466
BCR	-6189
FGF5	-6062
GRB2	-5790
MYO18A	-5665
TRIM24	-5643
NRAS	-5634
CUX1	-5038
FGFR1OP2	-4706
STAT5A	-4603
LRRFIP1	-4565
GAB1	-2761
FGF20	-2754
FGF4	-2221
FGF9	-2184
CEP43	-1989
SOS1	-1653
BAG4	-1640
ERLIN2	-1516
ZMYM2	-1173
HRAS	-327
PIK3CA	265
CPSF6	1521
STAT1	2001
GAB2	2954
FGF6	4751
FGF1	5299
FGFR1	5333
KRAS	7289
PLCG1	9968

---

REACTOME_HEMOSTASIS

REACTOME_HEMOSTASIS

	3
set	REACTOME_HEMOSTASIS
setSize	591
pANOVA	8.18e-05
s.dist	-0.0948
p.adjustANOVA	0.0096

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GYPA	-9448
H3C6	-9347
SELENOP	-9317
GNG8	-9227
FCER1G	-9221
HBG1	-9193
GP1BA	-9058
APLP2	-9015
PSG1	-8964
A1BG	-8960
H3C3	-8949
SRGN	-8944
CEACAM8	-8879
F2RL2	-8822
SPN	-8784
LCK	-8743
ITGAM	-8700
MAFG	-8655
JCHAIN	-8630
RAD51C	-8577

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GYPA	-9448.0
H3C6	-9347.0
SELENOP	-9317.0
GNG8	-9227.0
FCER1G	-9221.0
HBG1	-9193.0
GP1BA	-9058.0
APLP2	-9015.0
PSG1	-8964.0
A1BG	-8960.0
H3C3	-8949.0
SRGN	-8944.0
CEACAM8	-8879.0
F2RL2	-8822.0
SPN	-8784.0
LCK	-8743.0
ITGAM	-8700.0
MAFG	-8655.0
JCHAIN	-8630.0
RAD51C	-8577.0
PSG2	-8502.0
ITGA5	-8479.0
SLC16A8	-8454.0
GP1BB	-8361.0
ACTN1	-8358.0
AK3	-8307.0
RAP1B	-8270.0
PSG4	-8262.0
SPP2	-8253.0
P2RY12	-8136.0
ALB	-8122.0
CFD	-8091.0
GNG11	-8031.0
ADRA2B	-8016.0
IFNA8	-8008.0
MMRN1	-7983.0
STXBP3	-7968.0
NFE2	-7892.0
PPP2CB	-7833.0
GRB7	-7752.0
CD244	-7726.0
MAFK	-7712.0
TUBA8	-7702.0
IGF1	-7671.0
H3C8	-7667.0
PSG8	-7655.0
RHOB	-7636.0
ARRB2	-7590.0
AKAP10	-7571.0
PPP2R5B	-7552.0
GNG2	-7528.0
STXBP2	-7476.0
CD177	-7470.0
IFNA5	-7447.0
S100A10	-7420.0
KIF1C	-7359.0
SLC7A7	-7335.0
TREM1	-7298.0
RASGRP2	-7275.0
KIF12	-7270.0
SELL	-7247.0
SIRPA	-7231.0
GP5	-7154.0
GNB4	-7149.0
ECM1	-7114.0
GP9	-7090.0
MAFF	-6992.0
RAC2	-6931.0
PRKACG	-6896.0
MPL	-6868.0
CSK	-6864.0
CAPZB	-6824.0
PRKACB	-6812.0
TUBAL3	-6806.0
DOCK2	-6797.0
DAGLB	-6776.0
GATA5	-6750.0
PPBP	-6718.0
MYB	-6687.0
CXADR	-6600.0
HDAC2	-6527.0
CD36	-6515.0
DGKG	-6480.0
PIK3R1	-6466.0
PLAUR	-6455.0
WDR1	-6302.0
CDC42	-6295.0
P2RX7	-6264.0
ITGA2	-6235.0
PSG9	-6213.0
PDPN	-6211.0
P2RX5	-6202.0
RAD51B	-6081.0
CALM1	-6055.0
JAM3	-6048.0
F2RL3	-5978.0
TUBA3D	-5970.0
IFNA14	-5915.0
HBD	-5913.0
KIF22	-5833.0
DGKH	-5813.0
TUBA3C	-5799.0
GRB2	-5790.0
ABL1	-5751.0
DOCK7	-5741.0
F13B	-5729.0
SLC8A1	-5727.0
RAC1	-5691.0
MICAL1	-5690.0
NRAS	-5634.0
VEGFC	-5628.0
DGKE	-5589.0
ATP2A2	-5563.0
FAM3C	-5546.0
INPP5D	-5526.0
APOA1	-5516.0
ITGB2	-5419.0
P2RX1	-5410.0
LCP2	-5403.0
TOR4A	-5364.0
KIF13B	-5264.0
TUBB2A	-5173.0
SH2B2	-5155.0
SERPING1	-5089.0
PPP2R5C	-5022.0
PDE1B	-5018.0
GNB1	-4992.0
DGKZ	-4991.0
PTPN1	-4943.0
PDPK1	-4919.0
ITPR1	-4828.0
GUCY1A2	-4713.0
TGFB2	-4680.0
GNB3	-4659.0
APBB1IP	-4652.0
KIF5B	-4641.0
NOS3	-4616.0
RBSN	-4582.0
PRKCH	-4547.0
SLC7A6	-4520.0
EPCAM	-4517.0
GNG3	-4493.0
QSOX1	-4453.0
CLEC3B	-4446.0
CBX5	-4442.0
PLA2G4A	-4415.0
PROCR	-4382.0
PRKG2	-4381.0
ZFPM1	-4363.0
SLC8A3	-4355.0
PSG7	-4305.0
P2RX6	-4286.0
SERPINE1	-4246.0
RACGAP1	-4242.0
MFN1	-4228.0
ATP2A1	-4204.0
PSAP	-4188.0
ITGA10	-4176.0
SOD1	-4161.0
KIF1B	-4051.0
TIMP3	-4008.0
GTPBP2	-3972.0
C1QBP	-3893.0
DGKA	-3874.0
F2	-3871.0
BCAR1	-3851.0
SDC3	-3850.0
STIM1	-3815.0
GNA14	-3794.0
CALU	-3788.0
GNAQ	-3714.0
DOCK9	-3683.0
P2RX2	-3629.0
THBD	-3620.0
SCCPDH	-3615.0
KLC1	-3600.0
SCG3	-3596.0
ADRA2A	-3567.0
CD2	-3549.0
GNB5	-3516.0
IFNA7	-3509.0
IFNA1	-3508.0
ATP2B4	-3474.0
TUBB2B	-3465.0
TRPC6	-3460.0
GNG7	-3459.0
YWHAZ	-3448.0
RAP1A	-3445.0
SIRPG	-3442.0
KIF21B	-3398.0
SLC7A9	-3346.0
GNG4	-3344.0
SERPINB2	-3275.0
PTPN6	-3251.0
ATP1B1	-3250.0
KIF2A	-3214.0
GNA12	-3205.0
CEACAM3	-3187.0
SYK	-3183.0
GNA13	-3172.0
CEACAM5	-3167.0
JMJD1C	-3126.0
PDE1A	-3100.0
PRKAR2B	-2948.0
DGKD	-2947.0
TFPI	-2923.0
ALDOA	-2920.0
KIF3A	-2902.0
VCL	-2878.0
ITGA2B	-2859.0
DOCK10	-2854.0
MGLL	-2842.0
JAM2	-2837.0
F5	-2832.0
GNA15	-2817.0
PRKCD	-2784.0
TRPC3	-2694.0
MAPK1	-2642.0
RCOR1	-2587.0
PIK3CG	-2563.0
RARRES2	-2539.0
HBG2	-2528.0
PPP2CA	-2522.0
ANGPT2	-2515.0
FGR	-2506.0
PF4V1	-2482.0
PRKACA	-2469.0
CLU	-2465.0
CAPZA2	-2439.0
PRKCB	-2434.0
PHACTR2	-2408.0
SDC2	-2244.0
TUBB6	-2200.0
NHLRC2	-2138.0
PECAM1	-2108.0
OLA1	-2102.0
TUBA1A	-2074.0
SERPINA3	-2070.0
GATA2	-2027.0
CD44	-1968.0
MAPK14	-1965.0
SLC7A8	-1957.0
SERPINB6	-1898.0
SIN3A	-1837.0
PRTN3	-1806.0
ACTB	-1798.0
SRI	-1777.0
SLC7A5	-1762.0
HMG20B	-1727.0
PRKCZ	-1656.0
SOS1	-1653.0
GLG1	-1638.0
F11R	-1601.0
VPREB1	-1598.0
SH2B3	-1500.0
PIK3R2	-1452.0
PPP2R5E	-1359.0
SLC8A2	-1356.0
IRF2	-1342.0
FERMT3	-1338.0
GNB2	-1313.0
KCNMB2	-1259.0
TUBB1	-1249.0
IFNA2	-1244.0
CRK	-1152.0
PLAU	-1070.0
BRPF3	-1058.0
TUBB4A	-1022.0
TEK	-974.0
ITGA6	-906.0
SLC3A2	-865.0
KIF16B	-783.0
PROS1	-748.0
NOS2	-745.0
OLR1	-719.0
GUCY1B1	-661.0
TUBB8	-638.0
CD63	-609.0
SHC1	-599.0
ORAI2	-559.0
GNAT3	-553.0
H3C12	-520.0
SELP	-514.0
VWF	-494.0
APOB	-461.0
RASGRP1	-447.0
SDC4	-439.0
ANXA2	-401.0
LAT	-371.0
HRAS	-327.0
PIK3CB	-320.0
KIF20A	-275.0
PIK3R6	-226.0
SLC16A3	-221.0
PRKG1	-142.0
H3-3B	-135.0
RAF1	-132.0
ANGPT1	-88.0
MERTK	-62.0
DOCK6	-30.0
PFN1	93.0
LHFPL2	97.0
ITPR2	115.0
PRKCQ	124.0
SERPINC1	144.0
GATA3	173.0
PIK3CA	265.0
RHOG	285.0
PPIA	302.0
TUBA1C	306.0
SRC	374.0
KLC2	461.0
DOCK8	508.0
STX4	524.0
PHF21A	555.0
ATP2B1	658.0
TMX3	673.0
H3-3A	750.0
PRKAR1A	781.0
DGKB	792.0
ABCC4	823.0
CENPE	840.0
ITGB3	876.0
CYRIB	917.0
LYN	942.0
FGB	954.0
ITPK1	973.0
VTI1B	977.0
CAP1	994.0
APP	1001.0
ABHD12	1016.0
ATP1B3	1072.0
TUBA4A	1089.0
CD84	1103.0
CARMIL1	1114.0
KIFC2	1186.0
EHD1	1201.0
PRKCG	1271.0
VPS45	1275.0
ENDOD1	1287.0
PPIL2	1320.0
GNA11	1321.0
KIF5A	1336.0
CD74	1345.0
FYN	1368.0
KIF20B	1400.0
TTN	1485.0
TRPC7	1503.0
PLEK	1514.0
KIFAP3	1628.0
ITPR3	1682.0
F12	1740.0
MFN2	1766.0
IGF2	1808.0
PRKAR2A	1822.0
HRG	1842.0
MPIG6B	1846.0
PDE11A	1879.0
P2RX3	1897.0
PTK2	1917.0
KLC3	1986.0
SLC7A10	1999.0
TAGLN2	2005.0
PRKCE	2099.0
ACTN2	2109.0
KCNMB4	2133.0
CABLES1	2154.0
JAML	2156.0
VAV2	2223.0
YES1	2253.0
F11	2290.0
MAG	2328.0
ESAM	2390.0
P2RX4	2505.0
GNG13	2555.0
KIF19	2598.0
SELE	2645.0
CFL1	2658.0
ATP2A3	2684.0
PDE10A	2691.0
PAFAH2	2724.0
KIF21A	2726.0
COL1A1	2731.0
GNAI3	2785.0
PDGFB	2819.0
PROC	2855.0
VAV3	2988.0
HDAC1	3008.0
VEGFB	3049.0
H3C4	3114.0
PLAT	3131.0
MAPK3	3132.0
DOCK5	3142.0
DOCK4	3159.0
PICK1	3162.0
PRKAR1B	3180.0
ITGAV	3226.0
BSG	3294.0
KIFC1	3319.0
KIF4B	3361.0
GNAI1	3400.0
KLC4	3401.0
GNGT1	3417.0
TUBB3	3478.0
CDK2	3484.0
IFNA6	3495.0
RAPGEF3	3522.0
CD109	3572.0
IGLL1	3574.0
CABLES2	3578.0
ARRB1	3626.0
P2RY1	3641.0
KDM1A	3653.0
CHID1	3666.0
PCYOX1L	3697.0
PLCG2	3712.0
PPP2R5A	3729.0
MIF	3768.0
TP53	3808.0
CYB5R1	3816.0
PDGFA	3935.0
IRAG1	3985.0
IFNA13	4135.0
H3C7	4207.5
DOK2	4294.0
PCDH7	4297.0
PRKCA	4304.0
ACTN4	4307.0
KIF26B	4313.0
AKT1	4367.0
PRCP	4396.0
F7	4466.0
CAPZA1	4481.0
KIF3B	4582.0
KIF6	4660.0
LY6G6F	4684.0
DGKQ	4703.0
SERPINB8	4725.0
TGFB1	4753.0
IFNA16	4779.0
ZFPM2	4829.0
COL1A2	4840.0
SERPIND1	4867.0
H3C1	5045.0
CD9	5070.0
SERPINE2	5076.0
TUBA3E	5092.0
CAV1	5106.0
CEACAM6	5112.0
TLN1	5153.0
ORM1	5154.0
TBXA2R	5195.0
EHD3	5283.0
VAV1	5316.0
SELPLG	5347.0
ITGA1	5457.0
PIK3R3	5467.0
HSPA5	5469.0
PF4	5530.0
SLC16A1	5610.0
ITGB1	5635.0
TNFRSF10A	5672.0
TUBA4B	5703.0
DAGLA	5719.0
KIF2C	5720.0
ORAI1	5739.0
CDC37L1	5743.0
ITGAX	5900.0
RAB5A	5912.0
PDE9A	6030.0
LRP8	6124.0
FCAMR	6138.0
GPC1	6227.0
CD47	6300.0
GNAS	6345.0
ANGPT4	6354.0
PSG11	6424.0
EGF	6426.0
ITGA3	6548.0
APOH	6561.0
KIF27	6620.0
KIF26A	6693.0
KCNMB3	6695.0
GNG5	6696.0
F13A1	6705.0
GATA4	6841.0
PDE2A	6912.0
TEX264	6934.0
GNGT2	7037.0
GATA6	7065.0
IRF1	7069.0
SLC7A11	7082.0
EHD2	7139.0
WEE1	7150.0
MANF	7206.0
GRB14	7207.0
DOCK1	7220.0
KCNMA1	7233.0
DOCK3	7237.0
KRAS	7289.0
CLEC1B	7348.0
KIF23	7374.0
PPP2R1B	7392.0
PIK3R5	7410.0
PLG	7570.0
A2M	7658.0
H3C2	7722.0
F2R	7737.0
LEFTY2	7739.0
TF	7820.0
JAK2	7835.0
RAPGEF4	7846.0
H3C11	8004.0
FN1	8022.0
DGKI	8077.0
PDE5A	8106.0
HGF	8166.0
RAB27B	8190.0
MMP1	8318.0
GYPC	8322.0
KIF18A	8369.0
SH2B1	8407.0
AKAP1	8494.0
ATP1B2	8504.0
CTSW	8510.0
AHSG	8595.0
LGALS3BP	8682.0
KIF1A	8685.0
ATP2B2	8754.0
ITGA4	8819.0
PTPN11	8945.0
PPP2R1A	9045.0
ISLR	9046.0
SPARC	9047.0
GUCY1A1	9055.0
TNFRSF10D	9329.0
SDC1	9427.0
NOS1	9479.0
KIF18B	9614.0
TNFRSF10B	9621.0
KIF9	9635.0
AAMP	9653.0
GNG12	9662.0
GP6	9723.0
KIF3C	9844.0
ITGAL	9867.0
PLCG1	9968.0
ADRA2C	9991.0
CD48	10034.0
F3	10042.0
PSG5	10057.0
KIF15	10105.0
THBS1	10146.0
THPO	10147.0
KLKB1	10173.0
VEGFA	10223.0
FGA	10283.0
ANXA5	10343.0
GNG10	10359.0
TGFB3	10366.0
CD58	10483.0
CEACAM1	10485.0
ITIH4	10596.0
GNAI2	10680.0
CDK5	10685.0
PTGIR	10703.0
RHOA	10768.0
HBB	10875.0
SERPINF2	10963.0
PPP2R5D	11025.0
TUBA1B	11052.0
IFNA21	11080.0
SERPINA4	11098.0
H3C10	11238.0
FGG	11386.0
HABP4	11399.0
HBE1	11400.0
F10	11405.0
KIF25	11450.0
KIF2B	11472.0
ORM2	11474.0
KIF11	11598.0
KCNMB1	11677.0
ABHD6	11726.0
SERPINA5	11783.0
SERPINA1	11794.0
KNG1	11806.0
ITIH3	11832.0
VPREB3	11965.0
TUBB4B	12047.0
IFNB1	12214.0

---

REACTOME_SARS_COV_2_MODULATES_HOST_TRANSLATION_MACHINERY

REACTOME_SARS_COV_2_MODULATES_HOST_TRANSLATION_MACHINERY

	1601
set	REACTOME_SARS_COV_2_MODULATES_HOST_TRANSLATION_MACHINERY
setSize	46
pANOVA	0.000108
s.dist	0.33
p.adjustANOVA	0.0118

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS15A	11939
RPS13	11420
RPS2	11169
RPS12	10945
SNRPF	10863
RPS11	10361
RPS21	10276
RPS14	9890
RPS8	9803
RPS6	9691
RPS5	9380
RPS16	9206
SNRPD2	9094
RPS7	8958
RPS10	8500
SNRPB	7733
RPS18	7574
RPS28	7553
SNRPG	7349
SNRPD1	7039

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS15A	11939.0
RPS13	11420.0
RPS2	11169.0
RPS12	10945.0
SNRPF	10863.0
RPS11	10361.0
RPS21	10276.0
RPS14	9890.0
RPS8	9803.0
RPS6	9691.0
RPS5	9380.0
RPS16	9206.0
SNRPD2	9094.0
RPS7	8958.0
RPS10	8500.0
SNRPB	7733.0
RPS18	7574.0
RPS28	7553.0
SNRPG	7349.0
SNRPD1	7039.0
GEMIN5	6943.0
DDX20	6557.0
SNRPD3	6442.0
RPS26	6403.0
RPS29	6202.0
FAU	6182.0
RPSA	5509.0
RPS23	4694.0
GEMIN6	4536.0
RPS20	4325.0
RPS24	3750.0
RPS27A	3415.0
RPS15	3030.0
RPS9	2957.0
RPS27	2734.0
RPS3	1293.0
SMN1	64.5
SMN2	64.5
RPS3A	-578.0
GEMIN7	-2406.0
RPS27L	-2461.0
RPS19	-3548.0
RPS25	-4512.0
GEMIN2	-5476.0
GEMIN4	-6343.0
SNRPE	-7549.0

---

REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES

REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES

	1135
set	REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES
setSize	353
pANOVA	0.000136
s.dist	0.118
p.adjustANOVA	0.014

Top enriched genes

Top 20 genes

GeneID	Gene Rank
INMT	12234.0
RPL10L	12167.0
RPS15A	11939.0
DAO	11929.0
RPL7A	11625.0
PSMB11	11475.0
RPL15	11453.0
RPL12	11427.0
RPS13	11420.0
NNMT	11394.0
RPL30	11333.0
DDC	11244.0
HOGA1	11205.0
RPS2	11169.0
UBA52	11156.0
DIO1	11035.0
TPH1	11006.0
RPL13A	10972.5
RPS12	10945.0
SERINC1	10779.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
INMT	12234.0
RPL10L	12167.0
RPS15A	11939.0
DAO	11929.0
RPL7A	11625.0
PSMB11	11475.0
RPL15	11453.0
RPL12	11427.0
RPS13	11420.0
NNMT	11394.0
RPL30	11333.0
DDC	11244.0
HOGA1	11205.0
RPS2	11169.0
UBA52	11156.0
DIO1	11035.0
TPH1	11006.0
RPL13A	10972.5
RPS12	10945.0
SERINC1	10779.0
RPL36AL	10700.5
ASS1	10634.0
AGXT	10593.0
BCKDHA	10473.0
RPL22L1	10372.0
SLC25A44	10370.0
RPS11	10361.0
RPL10A	10334.0
RPS21	10276.0
RPL37	10269.0
LIPT1	10261.0
RPL28	10227.0
TAT	10167.0
TDO2	10149.0
SARDH	10144.0
PPM1K	10115.0
RPL9	10104.0
SDS	10082.0
PDHA2	10028.0
FMO1	10026.0
RPL23A	9993.0
RPS14	9890.0
MAT1A	9884.0
RPL14	9804.0
RPS8	9803.0
PSMC3	9795.0
RPLP1	9750.0
HAO1	9718.0
UROC1	9693.0
RPS6	9691.0
PSMC1	9539.0
ALDH4A1	9533.0
RPL27A	9530.0
RPL3	9494.0
ACAD8	9490.0
AIMP2	9481.0
CKMT2	9442.0
KARS1	9433.0
RPS5	9380.0
OAZ1	9364.0
OAZ2	9232.0
RPS16	9206.0
ASNS	9163.0
SRM	9020.0
BBOX1	9018.0
RPLP0	9015.0
RPL8	8995.0
MTR	8967.0
RPS7	8958.0
BCAT2	8940.0
AIMP1	8892.0
LIAS	8864.0
TSTD1	8807.0
OCA2	8788.0
RPL26L1	8771.0
BHMT	8572.0
HNMT	8556.0
LIPT2	8505.0
RPS10	8500.0
PSMB2	8481.0
MTRR	8462.0
PSMB9	8387.0
TPO	8374.0
RPL21	8358.0
MCCC2	8327.0
SERINC2	8316.0
PSME2	8279.0
PSMD8	8061.0
HDC	8060.0
TSHB	7937.0
SERINC3	7910.0
PSMC6	7767.0
RPL29	7724.0
RPL13	7681.0
ASL	7599.0
RPS18	7574.0
RPS28	7553.0
NMRAL1	7548.0
PSMB5	7505.0
CTH	7385.0
RARS1	7322.0
ADO	7280.0
PSMB3	7215.0
GLDC	7174.0
OAZ3	7021.0
RPL18	6982.0
AMD1	6903.0
RPL24	6818.0
ENOPH1	6767.0
DLST	6758.0
PIPOX	6750.0
IL4I1	6643.0
ACMSD	6610.0
HAL	6596.0
SLC44A1	6589.0
SECISBP2	6496.0
RPS26	6403.0
HPD	6313.0
SLC6A7	6312.0
PSMD13	6257.0
RPS29	6202.0
ALDH9A1	6201.0
FAU	6182.0
GOT1	6174.0
EPRS1	6108.0
AGMAT	6082.0
PAOX	5855.0
SCLY	5824.0
RPL36	5777.0
FAH	5750.0
ALDH6A1	5699.0
PSTK	5697.0
LARS1	5559.0
HAAO	5516.0
RPSA	5509.0
ECHS1	5400.0
GSR	5373.0
IARS1	5308.0
PRODH2	5090.0
NQO1	5073.0
BHMT2	4862.0
PSMD14	4844.0
PSMB6	4820.0
PSMC5	4808.0
DLD	4793.0
RPL11	4720.0
MCCC1	4699.0
RPS23	4694.0
PSAT1	4562.0
PHGDH	4426.0
RPS20	4325.0
AZIN1	4308.0
AFMID	4250.0
AGXT2	4242.0
AUH	4236.0
DBH	4182.0
SERINC4	4163.0
GLUD1	4079.0
BCKDHB	4022.0
MARS1	3885.0
SQOR	3796.0
RPS24	3750.0
FTCD	3746.0
SEPSECS	3656.0
NAALAD2	3649.0
ADI1	3629.0
SEM1	3569.0
GSTZ1	3453.0
PSMB8	3437.0
RPS27A	3415.0
SLC45A2	3404.0
RPL23	3223.0
PSMA7	3056.0
RPS15	3030.0
RPS9	2957.0
SLC6A12	2955.0
RPS27	2734.0
PSMA3	2680.0
CDO1	2669.0
SLC36A4	2664.0
ACAT1	2661.0
PYCR3	2590.0
RPL35	2573.0
PSME3	2564.0
RPL26	2485.0
TST	2451.0
BCKDK	2438.0
SHMT1	2368.0
DUOX2	2311.0
SLC5A5	2240.0
GRHPR	2231.0
RPL37A	2197.0
PSMC4	2167.0
MTAP	2078.0
PSMA6	2004.0
PAPSS2	1946.0
DUOX1	1907.0
PSMA4	1771.0
PSMC2	1501.0
RPL18A	1454.0
PSMB1	1426.0
PYCR2	1405.0
PRODH	1388.0
RPS3	1293.0
CRYM	1252.0
PSMA2	1209.0
HGD	1093.0
SRR	1052.0
RPL7	1003.0
EEF1E1	999.0
TH	835.0
ASRGL1	829.0
RPL22	817.0
SMOX	795.0
SLC25A12	729.0
GLS2	686.0
ALDH18A1	582.0
SLC25A13	500.0
GNMT	490.0
PSMD3	478.0
PHYKPL	452.0
RPL38	447.0
GADL1	442.0
PSMD2	365.0
PSMB4	130.0
DLAT	44.0
AMDHD1	-18.0
GLS	-21.0
PSMD5	-130.0
MPST	-203.0
EEFSEC	-209.0
SLC25A15	-225.0
KYAT3	-344.0
CGA	-349.0
CHDH	-410.0
PSMD6	-426.0
RPL4	-477.0
CKB	-480.0
GCDH	-555.0
DHTKD1	-568.0
RPS3A	-578.0
PDHX	-603.0
RPL6	-775.0
IDO2	-779.0
KYNU	-784.0
PSMD4	-820.0
PSMD1	-859.0
SLC3A2	-865.0
SEPHS2	-1016.0
ARG2	-1157.0
PXMP2	-1180.0
NAT8L	-1199.0
GLUL	-1235.0
SLC25A21	-1386.0
RIMKLA	-1395.0
RPL5	-1407.0
DMGDH	-1662.0
RPL3L	-1681.0
AANAT	-1682.0
GOT2	-1706.0
OGDH	-1711.0
CKMT1B	-1744.0
SLC7A5	-1762.0
DDO	-1765.0
ASPG	-1807.0
RPLP2	-1871.0
PAPSS1	-1912.0
SLC6A11	-1980.0
HIBCH	-2087.0
GATM	-2116.0
DIO2	-2266.0
SLC25A10	-2380.0
PSPH	-2395.0
QDPR	-2438.0
RPS27L	-2461.0
BCAT1	-2574.0
PSMA1	-2596.0
RIDA	-2614.0
RPL35A	-2635.0
SDSL	-2757.0
RPL32	-2777.0
PSMD9	-2789.0
CSAD	-2810.0
ACADSB	-2897.0
TXN2	-2962.0
SLC25A2	-3284.0
IDO1	-3471.0
RPS19	-3548.0
PSMA5	-3601.0
KYAT1	-3605.0
PAH	-3751.0
DCT	-3801.0
PSMF1	-3809.0
PSMD7	-3845.0
ASPA	-3939.0
AASS	-3941.0
APIP	-4084.0
RPL27	-4089.0
CARNMT1	-4125.0
IVD	-4174.0
GCAT	-4410.0
ODC1	-4462.0
RPS25	-4512.0
RPL39L	-4522.0
DIO3	-4525.0
HIBADH	-4574.0
PSMD11	-4724.0
PSMB10	-4752.0
GAMT	-4881.0
TPH2	-4936.0
RPL34	-5135.0
NDUFAB1	-5195.0
DBT	-5289.0
FOLH1	-5347.0
CPS1	-5573.0
PSMD12	-5677.0
HYKK	-5682.0
OAT	-5705.0
AZIN2	-5786.0
GPT	-5846.0
AHCY	-5935.0
PYCR1	-5962.0
ARG1	-5979.0
IYD	-6065.0
AADAT	-6086.0
RPL19	-6199.0
PSMB7	-6344.0
GPT2	-6348.0
CKM	-6459.0
PSME1	-6518.0
PCBD1	-6664.0
TXNRD1	-6768.0
MRI1	-6879.0
PSME4	-7369.0
TYRP1	-7399.0
DARS1	-7413.0
NAGS	-7432.0
KMO	-7483.0
GCSH	-7490.0
RPL41	-7598.0
PSMA8	-7628.0
TYR	-7668.0
SERINC5	-7675.0
RPL17	-7707.0
PNMT	-7790.0
ALDH7A1	-7960.0
RPL31	-8083.0
RIMKLB	-8117.0
CARNS1	-8424.0
PDHB	-8537.0
ETHE1	-9005.0
SUOX	-9052.0
AMT	-9569.0

---

REACTOME_METABOLISM_OF_RNA

REACTOME_METABOLISM_OF_RNA

	1313
set	REACTOME_METABOLISM_OF_RNA
setSize	675
pANOVA	0.000283
s.dist	0.0819
p.adjustANOVA	0.0274

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL10L	12167.0
RPS15A	11939.0
UTP15	11933.0
UTP3	11825.0
RPL7A	11625.0
PSMB11	11475.0
RPL15	11453.0
NUP88	11439.0
RPL12	11427.0
RPS13	11420.0
RPL30	11333.0
RPP40	11246.0
PWP2	11243.0
CDK7	11180.0
RPS2	11169.0
UBA52	11156.0
PNRC2	11136.0
PCF11	11011.0
RPL13A	10972.5
PHF5A	10957.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL10L	12167.0
RPS15A	11939.0
UTP15	11933.0
UTP3	11825.0
RPL7A	11625.0
PSMB11	11475.0
RPL15	11453.0
NUP88	11439.0
RPL12	11427.0
RPS13	11420.0
RPL30	11333.0
RPP40	11246.0
PWP2	11243.0
CDK7	11180.0
RPS2	11169.0
UBA52	11156.0
PNRC2	11136.0
PCF11	11011.0
RPL13A	10972.5
PHF5A	10957.0
RPS12	10945.0
NOP56	10925.0
POM121C	10915.0
SNRPF	10863.0
DIMT1	10852.0
BUD23	10819.0
EMG1	10792.0
RPL36AL	10700.5
EXOSC1	10538.0
TRMT6	10504.0
TBL3	10490.0
MFAP1	10464.0
CPSF2	10434.0
ELAC2	10429.0
MTERF4	10387.0
RPL22L1	10372.0
RPS11	10361.0
RPL10A	10334.0
PRCC	10322.0
RPS21	10276.0
RPL37	10269.0
SRSF1	10247.0
RPL28	10227.0
CNOT8	10189.0
MRM1	10130.0
HSPB1	10110.0
RPL9	10104.0
HNRNPH1	10100.0
PRPF38A	10088.0
SNRNP25	10081.0
NOL12	10080.0
LCMT2	10054.0
CSTF2T	9995.0
RPL23A	9993.0
WDR3	9954.0
UBC	9929.0
ZBTB8OS	9916.0
ISG20L2	9901.0
RPS14	9890.0
TRDMT1	9850.0
SRRM1	9819.0
RPL14	9804.0
RPS8	9803.0
PSMC3	9795.0
NUP42	9786.0
RPLP1	9750.0
RPS6	9691.0
TRMT13	9555.0
PSMC1	9539.0
RPL27A	9530.0
PRPF6	9522.0
LSM10	9511.0
RPL3	9494.0
LSM4	9478.0
EXOSC7	9477.0
TYW5	9451.0
TSEN34	9436.0
HNRNPA2B1	9425.0
THOC1	9417.0
RPS5	9380.0
TGS1	9320.0
PPWD1	9276.0
CNOT7	9247.0
SUPT5H	9245.0
RPS16	9206.0
SET	9186.0
THOC6	9113.0
UTP14C	9096.0
SNRPD2	9094.0
PPP2R1A	9045.0
CTU1	9034.0
BCAS2	9026.0
RPLP0	9015.0
WDR75	9012.0
RPL8	8995.0
SRSF5	8971.0
RRP1	8969.0
RPS7	8958.0
SNRPA	8938.0
UTP6	8920.0
FBL	8782.0
RPL26L1	8771.0
CRNKL1	8626.0
UBL5	8548.0
NUP43	8536.0
RPS10	8500.0
PSMB2	8481.0
NUP62	8463.0
POP7	8438.0
EXOSC6	8437.0
PSMB9	8387.0
PNO1	8386.0
NUP107	8380.0
RPL21	8358.0
C2orf49	8356.0
TSR1	8345.0
U2AF2	8337.0
PSME2	8279.0
UTP25	8243.0
IMP3	8195.0
CDC40	8183.0
NOL6	8156.0
XRN1	8150.0
NUP133	8148.0
PPIL3	8138.0
PSMD8	8061.0
TRNT1	8057.0
ETF1	8051.0
RCL1	8045.0
QTRT1	7966.0
TNKS1BP1	7916.0
BUD13	7896.0
POP4	7881.0
POLR2B	7880.0
FAM32A	7868.0
NIP7	7801.0
PSMC6	7767.0
SNRPB	7733.0
RPL29	7724.0
TRMT5	7716.0
DIS3	7695.0
RPL13	7681.0
GTF2F1	7678.0
SMG9	7655.0
LSM3	7636.0
PDCD11	7619.0
YBX1	7603.0
RRP9	7590.0
EIF4A2	7575.0
RPS18	7574.0
C9orf78	7573.0
RPS28	7553.0
PSMB5	7505.0
FTSJ3	7473.0
DDX1	7449.0
SRSF3	7436.0
SNRPG	7349.0
EXOSC4	7332.0
SRSF2	7323.0
TRMT12	7286.0
EXOSC10	7261.0
NUP155	7250.0
RRP7A	7236.0
PSMB3	7215.0
EIF4B	7164.0
WBP4	7105.0
RPP38	7085.0
EIF4A3	7076.0
SNRNP40	7053.0
SNRPD1	7039.0
RPL18	6982.0
GEMIN5	6943.0
URM1	6941.0
METTL1	6926.0
SRSF11	6914.0
CSTF1	6913.0
TPR	6866.0
RPL24	6818.0
DHX8	6809.0
SNIP1	6803.0
POLR2F	6801.0
FIP1L1	6797.0
MTO1	6759.0
MPHOSPH10	6753.0
DDX49	6700.0
LTV1	6683.0
RPPH1	6680.0
POLDIP3	6644.0
ALKBH8	6621.0
IMP4	6603.0
CNOT1	6582.0
DDX20	6557.0
DDX39A	6546.0
ELAVL1	6541.0
EBNA1BP2	6539.0
LENG1	6492.0
LSM6	6478.0
DCP1B	6477.0
SLBP	6457.0
DHX35	6446.0
SNRPD3	6442.0
CNOT3	6441.0
DDX5	6421.0
RPS26	6403.0
ADAT1	6369.0
EXOSC3	6366.0
TEX10	6364.0
QTRT2	6360.0
TSR3	6311.0
RPP25	6287.0
PSMD13	6257.0
MPHOSPH6	6221.0
TP53RK	6213.0
RPS29	6202.0
FAU	6182.0
ZMAT5	6172.0
PLRG1	6145.0
NAT10	6125.0
EPRS1	6108.0
NCBP2	6104.0
SMNDC1	6098.0
DCAF13	6054.0
APOBEC3B	6048.0
RNPS1	6016.0
PPIE	6004.0
SARNP	5977.0
NOL9	5960.0
PRPF31	5811.0
PPIL4	5789.0
RPL36	5777.0
RBM42	5746.0
TRMU	5744.0
DHX9	5737.0
SNRNP35	5718.0
RBM8A	5688.0
HSPA8	5687.0
MRM2	5649.0
RNPC3	5647.0
SUGP1	5642.0
LSM5	5617.0
MAPK11	5608.0
SNW1	5583.0
CWC22	5563.0
TRMT61B	5547.0
EXOSC8	5529.0
CTU2	5523.0
PES1	5518.0
RPSA	5509.0
CNOT6L	5448.0
WDR4	5439.0
PHAX	5411.0
NUP37	5379.0
SF3B3	5274.0
RPP14	5266.0
SRSF7	5251.0
SRRM2	5233.0
NUP93	5225.0
NXT1	5204.0
NUP188	5176.0
SMG1	5144.0
NUP160	4948.0
PSMD14	4844.0
PSMB6	4820.0
BUD31	4810.0
PSMC5	4808.0
WTAP	4785.0
ALYREF	4778.0
RPL11	4720.0
IK	4701.0
RPS23	4694.0
POLR2D	4651.0
WDR46	4598.0
XAB2	4547.0
GEMIN6	4536.0
CNOT9	4519.0
TSEN2	4429.0
NUP35	4415.0
TRMT1	4411.0
NOP10	4398.0
AKT1	4367.0
MAGOHB	4342.0
RPS20	4325.0
PRKCA	4304.0
HNRNPD	4274.0
WDR12	4190.0
PABPC1	4184.0
SF3B5	4175.0
POP5	4145.0
WBP11	4115.0
CSTF3	4098.0
YWHAB	4065.0
TRMT10A	4028.0
TRMT11	3999.0
NUP205	3947.0
PRORP	3897.0
SNRNP70	3851.0
POLR2A	3845.0
SEC13	3809.0
BOP1	3793.0
DDX21	3790.0
POLR2G	3785.0
HNRNPA1	3771.0
RPS24	3750.0
UTP20	3652.0
RANBP2	3650.0
CHERP	3594.0
SEM1	3569.0
NSRP1	3536.0
PAN2	3460.0
PSMB8	3437.0
SLU7	3426.0
RPS27A	3415.0
SAP18	3371.0
NOC4L	3359.0
PRPF18	3243.0
RPL23	3223.0
NUP54	3207.0
OSGEP	3199.0
CACTIN	3082.0
PSMA7	3056.0
SDE2	3052.0
RPS15	3030.0
CNOT4	3016.0
SRSF6	2975.0
RPS9	2957.0
RBM25	2945.0
TRMT10C	2933.0
POLR2H	2882.0
SNRPC	2798.0
DUS2	2789.0
TYW1	2777.0
EIF4E	2774.0
HNRNPK	2765.0
RPS27	2734.0
UTP18	2714.0
CWC15	2701.0
HEATR1	2687.0
PSMA3	2680.0
MTREX	2663.0
RBM7	2651.0
RPL35	2573.0
PSME3	2564.0
NUP98	2548.0
RPL26	2485.0
ZCRB1	2465.0
PNN	2331.0
CWC27	2261.0
PRPF4	2247.0
SNRPA1	2219.0
RPL37A	2197.0
TFB1M	2176.0
PELP1	2172.0
PSMC4	2167.0
TRA2B	2063.0
ZNF830	2057.0
ERI1	2024.0
TRMT9B	2006.0
PSMA6	2004.0
RTCB	1972.0
TUT7	1914.0
EXOSC9	1913.0
SEH1L	1872.0
HNRNPF	1863.0
ISY1	1861.0
PSMA4	1771.0
SNRNP200	1758.0
SKIC2	1756.0
CPSF1	1755.0
AQR	1716.0
THADA	1688.0
LSM7	1671.0
HSPA1A	1651.0
APOBEC3C	1558.0
TSEN54	1531.0
CPSF6	1521.0
PSMC2	1501.0
CDKAL1	1455.0
RPL18A	1454.0
PSMB1	1426.0
PPIG	1417.0
NOP58	1391.0
MAPKAPK2	1379.0
CHTOP	1347.0
PPIL2	1320.0
RPS3	1293.0
PPIL1	1292.0
SF3B1	1291.0
ZC3H11A	1267.0
PUS1	1265.0
PAPOLA	1255.0
SNRPB2	1219.0
TRMT112	1218.0
PSMA2	1209.0
NOL11	1185.0
TYW3	1161.0
IGF2BP3	1155.0
PRPF40A	1116.0
SF3A2	1095.0
RPL7	1003.0
NDC1	964.0
ERCC3	948.0
MRM3	927.0
LUC7L3	926.0
CPSF7	882.0
GTF2H1	860.0
RPL22	817.0
RRP36	684.0
HNRNPL	671.0
EXOSC5	599.0
PAN3	540.0
HNRNPM	495.0
PSMD3	478.0
METTL3	471.0
ADAT2	468.0
RPL38	447.0
PRKRIP1	444.0
SMG7	436.0
RNMT	433.0
UTP4	408.0
YJU2	386.0
PSMD2	365.0
POLR2I	261.0
SKIC3	204.0
WDR36	190.0
TPRKB	163.0
POLR2L	160.0
DCP1A	136.0
PSMB4	130.0
SMN1	64.5
SMN2	64.5
NSUN4	60.0
GTF2H5	30.0
SF3A3	-60.0
LSM8	-82.0
PSMD5	-130.0
SRSF9	-170.0
APOBEC3H	-172.0
SMG8	-184.0
CTNNBL1	-205.0
SF3A1	-215.0
POP1	-216.0
RBM5	-247.0
PUS3	-251.0
CCAR1	-256.0
NSUN6	-364.0
DHX38	-392.0
PSMD6	-426.0
CNOT2	-427.0
RPL4	-477.0
RPP21	-488.0
TCERG1	-521.0
XPO1	-547.0
ERCC2	-558.0
RPS3A	-578.0
HNRNPC	-677.0
TXNL4A	-762.0
PRPF8	-773.0
RPL6	-775.0
TNPO1	-797.0
DHX15	-805.0
PSMD4	-820.0
PCBP1	-827.0
PSMD1	-859.0
DDX41	-872.0
PUS7	-938.0
U2SURP	-996.0
PRPF3	-1074.0
NHP2	-1080.0
PPIH	-1150.0
PRPF19	-1161.0
RBM22	-1179.0
ANP32A	-1212.0
BYSL	-1216.0
HNRNPU	-1324.0
PPP1R8	-1374.0
MAGOH	-1401.0
RPL5	-1407.0
WDR33	-1450.0
UBB	-1544.0
RPL3L	-1681.0
WDR70	-1688.0
UTP11	-1775.0
RPLP2	-1871.0
KRR1	-1890.0
SYF2	-1902.0
DDX47	-1907.0
RIOK3	-1924.0
MAPK14	-1965.0
ADARB1	-1971.0
CWF19L2	-2014.0
POLR2K	-2038.0
NOB1	-2078.0
PATL1	-2147.0
FAM98B	-2186.0
CASC3	-2269.0
IGF2BP1	-2368.0
THOC5	-2375.0
GEMIN7	-2406.0
PARN	-2415.0
SMG5	-2432.0
DHX16	-2436.0
RPS27L	-2461.0
AAAS	-2517.0
EDC3	-2519.0
PPP2CA	-2522.0
EFTUD2	-2551.0
RNGTT	-2559.0
KHSRP	-2581.0
PSMA1	-2596.0
RPL35A	-2635.0
WDR18	-2661.0
DNAJC8	-2668.0
THOC3	-2743.0
NOP14	-2745.0
ADAR	-2763.0
RPL32	-2777.0
PRKCD	-2784.0
SRSF8	-2786.0
PSMD9	-2789.0
ACIN1	-2843.0
CWC25	-2846.0
EIF4A1	-2862.0
SNU13	-2895.0
CPSF3	-2903.0
SMU1	-2937.0
TFIP11	-2975.0
DCPS	-3046.0
CSNK1E	-3078.0
SNRNP27	-3143.0
UPF2	-3217.0
NCL	-3257.0
DHX37	-3279.0
EXOSC2	-3297.0
SF3B2	-3306.0
GCFC2	-3329.0
CCNH	-3354.0
ADAT3	-3364.0
RBM39	-3411.0
HNRNPR	-3441.0
YWHAZ	-3448.0
RPS19	-3548.0
U2AF1L4	-3589.0
PSMA5	-3601.0
GPATCH1	-3673.0
NUDT21	-3676.0
DDX52	-3707.0
ZMAT2	-3773.0
ZNF473	-3783.0
PSMF1	-3809.0
PSMD7	-3845.0
XPOT	-3861.0
CLP1	-3879.0
RPP30	-3898.0
NUP153	-3940.0
NUP210	-3969.0
GNL3	-3977.0
NUP50	-3978.0
LSM1	-4017.0
NCBP1	-4046.0
POLR2C	-4056.0
RPL27	-4089.0
BMS1	-4136.0
DDX23	-4141.0
EDC4	-4175.0
SF1	-4224.0
LSM11	-4262.0
APOBEC2	-4342.0
SRSF10	-4343.0
IGF2BP2	-4443.0
A1CF	-4468.0
CLNS1A	-4483.0
RPS25	-4512.0
RPL39L	-4522.0
RTRAF	-4581.0
ZFP36L1	-4594.0
PSMD11	-4724.0
SRSF4	-4726.0
PSMB10	-4752.0
GTF2F2	-4815.0
RIOK1	-4844.0
TRIT1	-4875.0
SART1	-4914.0
PRMT5	-4942.0
THG1L	-5090.0
RPL34	-5135.0
PUF60	-5180.0
PABPN1	-5187.0
NUP214	-5218.0
HBS1L	-5239.0
TRMT44	-5298.0
SRSF12	-5316.0
DDX42	-5329.0
CPSF4	-5354.0
NSUN2	-5427.0
GEMIN2	-5476.0
POLR2E	-5528.0
WDR43	-5566.0
PAIP1	-5613.0
SYMPK	-5638.0
SNRNP48	-5640.0
APOBEC4	-5644.0
PSMD12	-5677.0
DCP2	-5742.0
XRN2	-5760.0
NUP58	-5770.0
PPP2R2A	-5772.0
RIOK2	-5783.0
METTL14	-5803.0
RAN	-5878.0
GTF2H3	-5900.0
PTBP1	-5929.0
SMG6	-5936.0
USP39	-6003.0
FYTTD1	-6084.0
FCF1	-6110.0
RBM17	-6114.0
CNOT6	-6142.0
THUMPD1	-6146.0
SF3B4	-6147.0
RPL19	-6199.0
GEMIN4	-6343.0
PSMB7	-6344.0
CNOT10	-6368.0
UPF3A	-6399.0
CCDC12	-6454.0
PSME1	-6518.0
HNRNPA3	-6591.0
APOBEC3A	-6613.0
GAR1	-6632.0
EIF4G1	-6670.0
TSEN15	-6740.0
GSPT1	-6923.0
C1D	-6959.0
DDX6	-6979.0
RAE1	-6991.0
SNRPN	-7062.0
GTPBP3	-7117.0
FUS	-7155.0
MNAT1	-7169.0
WDR77	-7215.0
NXF1	-7234.0
DDX46	-7321.0
CNOT11	-7324.0
TUT4	-7351.0
PSME4	-7369.0
NUP85	-7391.0
SNUPN	-7411.0
LSM2	-7416.0
GTF2H4	-7444.0
UPF1	-7534.0
NT5C3B	-7536.0
SNRPE	-7549.0
CDC5L	-7578.0
RPL41	-7598.0
PSMA8	-7628.0
RBM28	-7647.0
CSNK1D	-7665.0
RPL17	-7707.0
SENP3	-7761.0
ZFP36	-7792.0
SRRT	-7961.0
POLR2J	-8074.0
RPL31	-8083.0
PCBP2	-8089.0
THOC7	-8121.0
GLE1	-8185.0
TRMT61A	-8192.0
NOP2	-8275.0
PDCD7	-8423.0
POM121	-8428.0
SKIC8	-8457.0
TNFSF13	-9077.0
DDX39B	-9244.0
APOBEC1	-9402.0
SF3B6	-9506.0

---

REACTOME_SIGNALING_BY_CYTOSOLIC_FGFR1_FUSION_MUTANTS

REACTOME_SIGNALING_BY_CYTOSOLIC_FGFR1_FUSION_MUTANTS

	286
set	REACTOME_SIGNALING_BY_CYTOSOLIC_FGFR1_FUSION_MUTANTS
setSize	18
pANOVA	0.000483
s.dist	-0.475
p.adjustANOVA	0.042

Top enriched genes

Top 20 genes

GeneID	Gene Rank
STAT3	-8571
CNTRL	-8135
STAT5B	-7052
PIK3R1	-6466
BCR	-6189
GRB2	-5790
MYO18A	-5665
TRIM24	-5643
CUX1	-5038
FGFR1OP2	-4706
STAT5A	-4603
LRRFIP1	-4565
CEP43	-1989
ZMYM2	-1173
PIK3CA	265
CPSF6	1521
STAT1	2001
GAB2	2954

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
STAT3	-8571
CNTRL	-8135
STAT5B	-7052
PIK3R1	-6466
BCR	-6189
GRB2	-5790
MYO18A	-5665
TRIM24	-5643
CUX1	-5038
FGFR1OP2	-4706
STAT5A	-4603
LRRFIP1	-4565
CEP43	-1989
ZMYM2	-1173
PIK3CA	265
CPSF6	1521
STAT1	2001
GAB2	2954

---

REACTOME_RRNA_MODIFICATION_IN_THE_NUCLEUS_AND_CYTOSOL

REACTOME_RRNA_MODIFICATION_IN_THE_NUCLEUS_AND_CYTOSOL

	1046
set	REACTOME_RRNA_MODIFICATION_IN_THE_NUCLEUS_AND_CYTOSOL
setSize	58
pANOVA	0.000487
s.dist	0.265
p.adjustANOVA	0.042

Top enriched genes

Top 20 genes

GeneID	Gene Rank
UTP15	11933
UTP3	11825
PWP2	11243
RPS2	11169
NOP56	10925
DIMT1	10852
BUD23	10819
EMG1	10792
TBL3	10490
WDR3	9954
RPS14	9890
RPS6	9691
UTP14C	9096
WDR75	9012
RPS7	8958
UTP6	8920
FBL	8782
PNO1	8386
UTP25	8243
IMP3	8195

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
UTP15	11933
UTP3	11825
PWP2	11243
RPS2	11169
NOP56	10925
DIMT1	10852
BUD23	10819
EMG1	10792
TBL3	10490
WDR3	9954
RPS14	9890
RPS6	9691
UTP14C	9096
WDR75	9012
RPS7	8958
UTP6	8920
FBL	8782
PNO1	8386
UTP25	8243
IMP3	8195
NOL6	8156
RCL1	8045
PDCD11	7619
RRP9	7590
RRP7A	7236
MPHOSPH10	6753
DDX49	6700
IMP4	6603
TSR3	6311
NAT10	6125
DCAF13	6054
WDR46	4598
NOP10	4398
UTP20	3652
NOC4L	3359
RPS9	2957
UTP18	2714
HEATR1	2687
NOP58	1391
TRMT112	1218
NOL11	1185
RRP36	684
UTP4	408
WDR36	190
NHP2	-1080
UTP11	-1775
KRR1	-1890
DDX47	-1907
NOP14	-2745
SNU13	-2895
DHX37	-3279
DDX52	-3707
BMS1	-4136
WDR43	-5566
FCF1	-6110
THUMPD1	-6146
GAR1	-6632
NOP2	-8275

---

REACTOME_SIGNALING_BY_GPCR

REACTOME_SIGNALING_BY_GPCR

	593
set	REACTOME_SIGNALING_BY_GPCR
setSize	673
pANOVA	0.000601
s.dist	-0.0775
p.adjustANOVA	0.0478

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CCL4	-9579
TAS2R43	-9559
CCL22	-9530
UCN	-9454
P2RY13	-9357
RXFP4	-9345
GRK2	-9290
MLNR	-9259
CCL7	-9255
GPR32	-9243
GNG8	-9227
RGS10	-9181
GALR3	-9160
TAS2R60	-9092
GHSR	-9081
GPR84	-9076
CCL19	-9066
SCT	-9054
WNT10A	-9019
WNT6	-9004

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CCL4	-9579
TAS2R43	-9559
CCL22	-9530
UCN	-9454
P2RY13	-9357
RXFP4	-9345
GRK2	-9290
MLNR	-9259
CCL7	-9255
GPR32	-9243
GNG8	-9227
RGS10	-9181
GALR3	-9160
TAS2R60	-9092
GHSR	-9081
GPR84	-9076
CCL19	-9066
SCT	-9054
WNT10A	-9019
WNT6	-9004
TAS2R13	-8946
RLN3	-8916
ACKR3	-8890
DRD4	-8865
RGS21	-8837
GNAT1	-8827
F2RL2	-8822
HTR2B	-8789
ANXA1	-8752
CX3CR1	-8671
C3AR1	-8646
S1PR5	-8640
RGS14	-8639
TAS2R14	-8620
TAS2R10	-8608
TSHR	-8556
ITGA5	-8479
TRHR	-8471
TAS2R41	-8434
CCL1	-8369
CXCL11	-8326
CALCA	-8306
RAMP2	-8282
KEL	-8277
CCKBR	-8220
CCR9	-8204
CCL25	-8149
P2RY12	-8136
PROKR1	-8066
FZD2	-8056
PRLHR	-8055
ADRB3	-8046
ADRB1	-8038
GNG11	-8031
ADRA2B	-8016
TAC3	-8013
APLNR	-7900
GPR31	-7893
PDE3B	-7839
PPP2CB	-7833
HTR1B	-7773
ARHGEF5	-7746
NPB	-7694
RXFP2	-7650
RHOB	-7636
PPP1R1B	-7632
ARRB2	-7590
TAS1R3	-7588
CALCRL	-7566
SAA1	-7544
GNG2	-7528
GPR18	-7507
CCR4	-7487
POMC	-7482
NMUR1	-7471
PLPPR3	-7373
RASGRP2	-7275
PROKR2	-7272
CORT	-7254
GNB4	-7149
ARHGEF38	-7146
QRFPR	-7136
GPSM1	-7124
XCL2	-7118
PTH2	-7061
PDYN	-7017
GPHA2	-6967
HCRTR2	-6955
GPR65	-6903
PRKACG	-6896
PRKACB	-6812
NPFF	-6807
DAGLB	-6776
GPR83	-6775
PTGDR	-6773
ADM2	-6747
GPR4	-6723
PPBP	-6718
ADORA2A	-6651
FZD8	-6620
CCK	-6513
ADGRE5	-6506
NTSR2	-6495
RGS4	-6484
DGKG	-6480
PPP3CC	-6471
PIK3R1	-6466
NPY5R	-6433
WNT16	-6376
OXGR1	-6329
CDC42	-6295
ACKR1	-6291
TAS2R3	-6283
TAS2R38	-6241
ARHGEF17	-6232
TAS2R42	-6225
GIPR	-6206
TAS2R1	-6100
CXCR2	-6098
CALM1	-6055
RGS17	-6026
HRH4	-6015
TACR3	-6012
F2RL3	-5978
OXER1	-5958
GRP	-5926
ADRA1D	-5922
RGS2	-5888
CALCR	-5885
GRM5	-5861
PDE8B	-5830
DGKH	-5813
FFAR3	-5793
GRB2	-5790
NBEA	-5776
ADCY3	-5699
TAS2R31	-5692
P2RY14	-5671
WNT10B	-5656
LTB4R	-5651
NRAS	-5634
CCR8	-5601
DGKE	-5589
PCP2	-5567
SST	-5540
OPN5	-5523
PREX1	-5505
ARHGEF37	-5464
GRM7	-5422
TAS2R39	-5416
TAS2R50	-5370
GPR183	-5366
ARHGEF1	-5341
GALR2	-5323
MC2R	-5231
RRH	-5200
DRD5	-5188
PROK2	-5168
ADCY7	-5111
ARHGEF25	-5085
GPR27	-5041
PDE1B	-5018
GNB1	-4992
DGKZ	-4991
FZD3	-4974
RGS9	-4964
TAS2R40	-4953
NPFFR2	-4937
PDPK1	-4919
SOS2	-4884
ITPR1	-4828
AHCYL1	-4817
ROCK2	-4775
GNRHR	-4749
GNB3	-4659
ADGRE2	-4648
FZD10	-4634
PRKCH	-4547
WNT9B	-4544
CCR10	-4519
GNG3	-4493
PDE4C	-4451
LHCGR	-4436
PLA2G4A	-4415
LPAR2	-4412
S1PR2	-4387
ARHGEF2	-4373
RXFP3	-4365
ADCYAP1	-4315
PDE7B	-4306
PLCB2	-4301
PENK	-4250
TAAR9	-4221
PSAP	-4188
WNT3A	-4124
TAS2R7	-4113
PTH2R	-4092
FSHR	-4086
GABBR1	-4082
TIAM1	-4055
DGKA	-3874
F2	-3871
ABR	-3826
FZD5	-3808
PDE7A	-3797
GNA14	-3794
FZD7	-3781
AKT3	-3729
GNAQ	-3714
HCRTR1	-3659
PDE1C	-3646
XCR1	-3626
ADRA2A	-3567
GNB5	-3516
TRPC6	-3460
GNG7	-3459
HTR4	-3427
PLPPR2	-3424
ARHGEF15	-3385
ARHGEF26	-3358
GNG4	-3344
NPBWR2	-3305
TAS2R9	-3287
SMO	-3246
GNA12	-3205
CRHR1	-3196
GNA13	-3172
PDE1A	-3100
RASGRF2	-3090
CHRM3	-3031
PRKAR2B	-2948
DGKD	-2947
PLEKHG5	-2945
TAS2R8	-2901
PYY	-2885
MGLL	-2842
GNA15	-2817
PRKCD	-2784
GRK3	-2779
ADCY9	-2758
NMUR2	-2716
TRPC3	-2694
LTB4R2	-2692
SSTR5	-2658
KISS1R	-2656
MAPK1	-2642
RGS13	-2602
PTGER1	-2588
OPRD1	-2577
PIK3CG	-2563
PTGER3	-2543
PPP2CA	-2522
PLPPR4	-2479
PRKACA	-2469
MTNR1A	-2466
PRKCB	-2434
FGD4	-2424
CHRM4	-2345
PLXNB1	-2343
CCL28	-2262
OXT	-2245
OPN1SW	-2207
CHRM5	-2206
WNT2	-2121
HEBP1	-2057
MCHR2	-2033
ADGRE3	-2004
AGTR1	-1964
GRK6	-1945
PAK1	-1934
GPR25	-1929
RGS3	-1926
ADCY8	-1894
PTGFR	-1816
NPBWR1	-1776
RAMP3	-1709
CD55	-1673
SOS1	-1653
CYSLTR2	-1603
CXCL1	-1482
PIK3R2	-1452
DHH	-1436
GPSM2	-1420
AVPR1A	-1350
GNB2	-1313
CAMKK1	-1226
CCL23	-1093
PDE4A	-1071
FZD6	-1064
RHOC	-1057
OPRL1	-1025
TAC1	-1023
GNAL	-1014
AVPR1B	-1007
ADCY6	-982
PTH1R	-967
PLCB1	-930
OPRK1	-892
FFAR4	-831
LPAR5	-801
FZD9	-785
PPP1CA	-742
PTGDR2	-730
GPER1	-684
MC1R	-679
SHC1	-599
FPR1	-557
GNAT3	-553
PPP3CA	-552
GHRL	-548
SSTR1	-459
RASGRP1	-447
PPP3R1	-435
PLCB3	-381
WNT2B	-372
GRM3	-370
CGA	-349
PDE4B	-338
DRD3	-328
HRAS	-327
GIP	-305
RGS18	-304
PTH	-230
PIK3R6	-226
PTCH1	-198
FGD3	-195
RGS20	-185
HCAR2	-125
AKAP13	-117
MLN	-109
OPN3	-98
CXCL6	-38
XCL1	107
ITPR2	115
PRKCQ	124
PNOC	131
RGS5	154
HRH3	155
TAS2R19	232
PIK3CA	265
ARHGEF18	309
EDNRB	350
MC3R	354
SRC	374
VIP	417
CXCL9	423
CXCL16	434
PTCH2	449
CAMK2D	480
MAPK7	576
ARHGEF40	593
SHH	611
SUCNR1	636
GRK5	645
PMCH	751
FZD1	761
PDE8A	773
PRKAR1A	781
DGKB	792
GRM2	818
CCL2	826
TIAM2	880
GPR176	910
OPRM1	971
APP	1001
S1PR1	1006
ABHD12	1016
PDE3A	1060
SSTR4	1065
HTR1E	1068
SSTR3	1070
UTS2R	1096
CASR	1106
ADORA2B	1129
ARHGEF16	1135
ACKR2	1165
GNRH1	1202
MC4R	1203
GPBAR1	1235
IHH	1263
PRKCG	1271
NMU	1272
GNA11	1321
S1PR3	1358
CAMKK2	1375
CCL13	1380
RGS16	1381
CAMK2G	1402
ARHGEF19	1427
VIPR1	1462
RLN2	1478
TRPC7	1503
ADM	1508
PLEKHG2	1532
PPP3CB	1591
TAS2R4	1641
ECE1	1676
ITPR3	1682
PDE4D	1712
SSTR2	1790
GPR68	1815
PRKAR2A	1822
CXCR4	1870
PDE11A	1879
NMB	1900
NET1	2019
TACR1	2029
TAS2R16	2044
PRKCE	2099
RXFP1	2120
GAL	2122
HRH1	2130
WNT3	2159
CX3CL1	2162
CAMK4	2199
HTR5A	2203
VAV2	2223
FPR3	2343
HRH2	2402
ADCY4	2412
NGEF	2430
TRH	2494
GNG13	2555
CALCB	2600
PDE10A	2691
ITSN1	2744
RGR	2764
TRIO	2782
GNAI3	2785
ARHGEF7	2804
GPR20	2822
TAAR6	2918
PLPPR1	2922
TAAR5	2924
CRHBP	2986
VAV3	2988
WNT4	3010
CREB1	3039
PTHLH	3047
MAPK3	3132
PRKAR1B	3180
GRM1	3201
WNT11	3228
GPR45	3268
GRM8	3297
GNAI1	3400
GNGT1	3417
CXCL10	3493
C5	3528
ARRB1	3626
ARHGEF3	3633
P2RY1	3641
RPS6KA2	3707
ARHGEF10	3718
HTR6	3863
HCAR1	3892
NPFFR1	3904
TAS2R46	4008
RGS7	4014
DRD1	4052
C5AR1	4117
CRH	4166
NLN	4298
PRKCA	4304
AKT1	4367
CCR3	4387
F2RL1	4463
ECT2	4492
AGT	4495
GPSM3	4508
ROCK1	4510
NPY2R	4538
CMKLR1	4567
DGKQ	4703
GPR132	4755
C3	4811
GPR150	4843
ECE2	4845
HCRT	4885
OXTR	4910
DRD2	4932
NMBR	5101
ADCY2	5119
CXCL8	5133
PPY	5160
RGS19	5161
TBXA2R	5195
CHRM2	5206
TACR2	5228
VIPR2	5235
VAV1	5316
GCG	5341
GPR39	5371
FPR2	5380
RGS8	5383
ARHGEF4	5403
PIK3R3	5467
PF4	5530
UTS2B	5548
AKT2	5582
TAS1R2	5632
ITGB1	5635
RGS22	5658
HTR1A	5682
EDN1	5700
NPS	5702
DAGLA	5719
GPR15	5741
AVP	5957
GPRC6A	6025
LPAR1	6123
GNRH2	6200
MTNR1B	6264
GABBR2	6281
GPR37	6318
HTR1F	6322
GNAS	6345
SCTR	6460
RHO	6479
RGS11	6503
HTR7	6634
GNG5	6696
OBSCN	6762
GRM6	6828
CCL3	6831
RGS1	6833
LPAR3	6867
GHRHR	6892
ARHGEF12	6894
PDE2A	6912
CNR2	6939
GNGT2	7037
TAS1R1	7063
RAMP1	7070
P2RY6	7078
GPR35	7225
KRAS	7289
EDN3	7293
GLP1R	7299
KALRN	7328
CXCL3	7389
PPP2R1B	7392
PIK3R5	7410
GALR1	7488
RGS6	7502
PTAFR	7533
ADORA3	7589
RGS12	7606
ADGRE1	7670
CCR7	7671
NTSR1	7673
CXCR5	7691
INSL5	7698
F2R	7737
CXCL2	7749
WNT9A	7810
ARHGEF39	7838
TSHB	7937
FN1	8022
DGKI	8077
PLCB4	8094
EDN2	8111
MCF2L	8113
HTR1D	8140
WNT7B	8170
CRHR2	8249
ADRA1A	8253
CCR1	8254
PTGER4	8290
PLPPR5	8383
FFAR2	8389
UCN3	8404
EDNRA	8459
ADORA1	8464
S1PR4	8495
WNT5A	8544
GNAT2	8547
WNT1	8615
ADCY1	8656
TAS2R5	8657
INSL3	8666
CXCL13	8708
HBEGF	8713
FGD2	8730
LPAR6	8756
CCRL2	8791
NPW	8796
KPNA2	8879
NPY	8903
ADRA1B	8998
PPP2R1A	9045
ADRB2	9105
UTS2	9127
GRM4	9166
C5AR2	9202
RPS6KA1	9214
ARHGEF10L	9267
NPY1R	9270
ADCYAP1R1	9274
KISS1	9302
CXCL12	9338
GNG12	9662
BDKRB2	9669
NMS	9671
CNR1	9682
HTR2A	9684
GPR17	9687
LHB	9816
GNAZ	9839
CCL16	9889
TAS2R20	9914
MCHR1	9989
ADRA2C	9991
QRFP	9997
EGFR	10025
GPR55	10045
CAMK2B	10096
PTGER2	10169
NPSR1	10179
GLP2R	10205
P2RY11	10213
CCR6	10314
MC5R	10330
GNG10	10359
PROK1	10367
FSHB	10463
RGSL1	10589
ARHGEF11	10590
BDKRB1	10623
GNAI2	10680
CDK5	10685
WNT8A	10697
PTGIR	10703
WNT8B	10722
ARHGEF33	10723
GPR37L1	10749
RHOA	10768
GHRH	10808
PRLH	10862
CCR2	10929
ADCY5	10951
P2RY2	11000
PPP2R5D	11025
CXCR1	11027
OPN4	11047
CAMK2A	11048
WNT7A	11060
CCL17	11082
FZD4	11095
MMP3	11104
TAAR1	11348
UCN2	11373
GAST	11408
CXCL5	11432
TAS2R30	11468
CCL20	11499
CCL11	11543
TAAR2	11549
FFAR1	11640
CCR5	11646
GPHB5	11669
IAPP	11713
ABHD6	11726
CCKAR	11732
CHRM1	11762
KNG1	11806
CXCR6	11940
CCL21	12020
NTS	12076
CCL5	12108
ACKR4	12168
TAAR8	12199
CCL27	12275

---

REACTOME_KERATINIZATION

REACTOME_KERATINIZATION

	1073
set	REACTOME_KERATINIZATION
setSize	210
pANOVA	0.000611
s.dist	0.137
p.adjustANOVA	0.0478

Top enriched genes

Top 20 genes

GeneID	Gene Rank
KRTAP8-1	12354
KRT16	12330
LCE2C	12327
KRTAP10-2	12235
KRTAP4-7	12213
KRT76	12190
LCE4A	12087
KRTAP5-10	12053
KRTAP9-9	12046
KRTAP10-10	12021
KRTAP1-3	11993
KRTAP23-1	11950
LCE2D	11915
KRT23	11864
KRTAP3-1	11861
KRT82	11836
KRT79	11809
KRT4	11777
KRTAP17-1	11756
KRT15	11744

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
KRTAP8-1	12354
KRT16	12330
LCE2C	12327
KRTAP10-2	12235
KRTAP4-7	12213
KRT76	12190
LCE4A	12087
KRTAP5-10	12053
KRTAP9-9	12046
KRTAP10-10	12021
KRTAP1-3	11993
KRTAP23-1	11950
LCE2D	11915
KRT23	11864
KRTAP3-1	11861
KRT82	11836
KRT79	11809
KRT4	11777
KRTAP17-1	11756
KRT15	11744
KRT6C	11731
KRT5	11708
KRTAP1-4	11706
SPRR3	11580
KRT71	11553
KRTAP5-7	11524
KRTAP5-8	11397
LCE1E	11372
KRT33A	11321
KRTAP19-1	11302
KRT37	11143
IVL	11026
LCE2B	11014
KRTAP5-4	10866
KRT74	10826
KRT24	10817
KRTAP9-4	10675
KRTAP12-2	10631
DSP	10599
KRTAP4-11	10587
KRTAP13-2	10488
KRTAP10-5	10441
KRTAP25-1	10423
KRT26	9863
KRT20	9831
KRTAP10-8	9755
KRT80	9608
SPRR2F	9537
LCE6A	9504
JUP	9262
LCE1C	9241
KRT40	9139
KLK14	9024
PCSK6	8986
KRT35	8965
LCE1B	8889
KRT1	8883
KRTAP2-1	8862
KRT32	8640
SPINK5	8635
LCE5A	8431
KRTAP5-2	8377
KRTAP4-3	8367
KRTAP10-4	8311
SPRR2G	8196
KRT33B	8116
SPRR2E	8039
KRTAP10-6	7819
KRT38	7792
DSG4	7705
KRT25	7602
LCE3B	7528
KRT78	7379
KRT28	7354
LIPJ	7217
KRTAP21-3	7066
CDSN	6839
KRT3	6780
PERP	6601
DSC1	6482
KRT10	6402
KRTAP15-1	6263
KRTAP2-3	6206
KRT73	6195
ST14	6175
KRT13	6144
KRTAP13-3	6039
KRTAP4-8	6001
SPRR2A	5787
KAZN	5772
KRTAP9-1	5692
TGM1	5619
KRT8	5606
KRTAP10-9	5580
KRTAP20-1	5415
KRTAP19-3	5409
KRTAP9-6	5329
LIPK	5267
KRTAP6-3	5246
KRT39	5050
TGM5	4905
LIPM	4758
LCE2A	4637
KRTAP1-1	4497
DSG1	4480
KRTAP11-1	4151
DSG3	3773
PI3	3689
KRT84	3527
KRT75	3347
SPRR2D	3219
KRTAP21-1	3122
KRTAP19-8	3106
KRTAP4-4	2984
KRT31	2850
CELA2A	2588
KRTAP19-5	2506
KRTAP10-1	2254
PKP1	2211
KRT77	2206
KRT19	2195
CAPNS1	2126
LCE3E	1720
KRT72	1606
KRTAP26-1	1541
KRTAP10-7	1481
KRT27	1284
KRT83	1233
PKP3	1100
KRTAP2-2	1033
KLK12	821
KRT2	472
KRTAP2-4	415
KRTAP4-1	331
FURIN	-33
KRTAP6-1	-428
LCE3D	-431
KRTAP27-1	-752
KLK8	-944
FLG	-980
PPL	-1177
LCE1F	-1184
KRT9	-1277
KRTAP9-3	-1278
KRTAP10-11	-1371
KRTAP12-4	-1416
KRTAP24-1	-1530
PRSS8	-1560
KRTAP5-6	-1562
KRTAP6-2	-1580
KRTAP13-1	-1821
KRT18	-1866
LELP1	-2124
PKP4	-2303
DSG2	-2633
KLK5	-2844
KRTAP19-2	-3051
KRTAP22-1	-3330
KRTAP3-3	-3558
CASP14	-4150
KRTAP5-5	-4251
PKP2	-4509
CAPN1	-4611
RPTN	-4747
KRT81	-4846
KRT34	-4883
SPINK6	-5261
KRTAP5-9	-5351
KRTAP16-1	-5486
DSC2	-5491
KRT17	-5503
EVPL	-5717
TCHH	-5775
KRTAP3-2	-5875
KRT12	-5916
KRTAP10-12	-6042
KRTAP12-1	-6118
KRTAP19-7	-6156
KRT36	-6185
DSC3	-6331
KRTAP4-2	-6388
KRTAP12-3	-6594
KRTAP1-5	-6704
KRTAP19-6	-6796
KRTAP9-2	-6851
SPINK9	-6944
LCE1A	-7056
KRT7	-7613
KRTAP19-4	-7677
KRT85	-7710
SPRR1B	-7735
LCE3A	-7766
KRTAP4-6	-7791
KRT6A	-8323
KRTAP10-3	-8374
KRTAP5-1	-8586
KLK13	-8590
KRTAP29-1	-8636
LIPN	-8651
KRTAP4-5	-8652
KRTAP20-2	-8715
CSTA	-8750
SPRR1A	-8757
KRTAP21-2	-8838
KRTAP13-4	-8920
KRT6B	-8928
KRT86	-9030
KRT14	-9143
KRTAP5-3	-9202
KRTAP5-11	-9397

---

REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

	1082
set	REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE
setSize	125
pANOVA	0.000768
s.dist	0.174
p.adjustANOVA	0.0573

Top enriched genes

Top 20 genes

GeneID	Gene Rank
KRT16	12330
LCE2C	12327
KRT76	12190
LCE4A	12087
LCE2D	11915
KRT23	11864
KRT82	11836
KRT79	11809
KRT4	11777
KRT15	11744
KRT6C	11731
KRT5	11708
SPRR3	11580
KRT71	11553
LCE1E	11372
KRT33A	11321
KRT37	11143
IVL	11026
LCE2B	11014
KRT74	10826

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
KRT16	12330
LCE2C	12327
KRT76	12190
LCE4A	12087
LCE2D	11915
KRT23	11864
KRT82	11836
KRT79	11809
KRT4	11777
KRT15	11744
KRT6C	11731
KRT5	11708
SPRR3	11580
KRT71	11553
LCE1E	11372
KRT33A	11321
KRT37	11143
IVL	11026
LCE2B	11014
KRT74	10826
KRT24	10817
DSP	10599
KRT26	9863
KRT20	9831
KRT80	9608
SPRR2F	9537
LCE6A	9504
JUP	9262
LCE1C	9241
KRT40	9139
KLK14	9024
PCSK6	8986
KRT35	8965
LCE1B	8889
KRT1	8883
KRT32	8640
SPINK5	8635
LCE5A	8431
SPRR2G	8196
KRT33B	8116
SPRR2E	8039
KRT38	7792
DSG4	7705
KRT25	7602
LCE3B	7528
KRT78	7379
KRT28	7354
LIPJ	7217
CDSN	6839
KRT3	6780
PERP	6601
DSC1	6482
KRT10	6402
KRT73	6195
ST14	6175
KRT13	6144
SPRR2A	5787
KAZN	5772
TGM1	5619
KRT8	5606
LIPK	5267
KRT39	5050
TGM5	4905
LIPM	4758
LCE2A	4637
DSG1	4480
DSG3	3773
PI3	3689
KRT84	3527
KRT75	3347
SPRR2D	3219
KRT31	2850
CELA2A	2588
PKP1	2211
KRT77	2206
KRT19	2195
CAPNS1	2126
LCE3E	1720
KRT72	1606
KRT27	1284
KRT83	1233
PKP3	1100
KLK12	821
KRT2	472
FURIN	-33
LCE3D	-431
KLK8	-944
FLG	-980
PPL	-1177
LCE1F	-1184
KRT9	-1277
PRSS8	-1560
KRT18	-1866
LELP1	-2124
PKP4	-2303
DSG2	-2633
KLK5	-2844
CASP14	-4150
PKP2	-4509
CAPN1	-4611
RPTN	-4747
KRT81	-4846
KRT34	-4883
SPINK6	-5261
DSC2	-5491
KRT17	-5503
EVPL	-5717
TCHH	-5775
KRT12	-5916
KRT36	-6185
DSC3	-6331
SPINK9	-6944
LCE1A	-7056
KRT7	-7613
KRT85	-7710
SPRR1B	-7735
LCE3A	-7766
KRT6A	-8323
KLK13	-8590
LIPN	-8651
CSTA	-8750
SPRR1A	-8757
KRT6B	-8928
KRT86	-9030
KRT14	-9143

---

REACTOME_OLFACTORY_SIGNALING_PATHWAY

REACTOME_OLFACTORY_SIGNALING_PATHWAY

	628
set	REACTOME_OLFACTORY_SIGNALING_PATHWAY
setSize	348
pANOVA	0.00085
s.dist	0.104
p.adjustANOVA	0.0607

Top enriched genes

Top 20 genes

GeneID	Gene Rank
OR56B4	12352
OR51G1	12343
OR56A5	12297
OR10J3	12293
OR1G1	12256
OR2H2	12247
OR2S2	12239
OR51G2	12230
OR2Y1	12206
OR10A3	12173
OR10G3	12166
OR13J1	12154
OR10Z1	12152
OR13C4	12134
OR6K3	12090
OR9K2	12068
OR1N1	12064
OR1J4	12041
OR51Q1	12039
OR2L8	12037

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
OR56B4	12352.0
OR51G1	12343.0
OR56A5	12297.0
OR10J3	12293.0
OR1G1	12256.0
OR2H2	12247.0
OR2S2	12239.0
OR51G2	12230.0
OR2Y1	12206.0
OR10A3	12173.0
OR10G3	12166.0
OR13J1	12154.0
OR10Z1	12152.0
OR13C4	12134.0
OR6K3	12090.0
OR9K2	12068.0
OR1N1	12064.0
OR1J4	12041.0
OR51Q1	12039.0
OR2L8	12037.0
OR51T1	11969.0
OR5AU1	11954.0
OR52R1	11911.0
OR4D9	11907.0
OR52E2	11881.0
OR51S1	11875.0
RTP2	11850.0
OR51V1	11843.0
OR5AK2	11830.0
OR10S1	11766.0
OR2T3	11758.0
OR6C65	11743.0
OR10K2	11704.0
OR51D1	11698.0
OR8B8	11691.0
OR1L8	11651.0
OR51E1	11579.0
OR52E4	11559.0
OR52E6	11538.0
OR1F1	11435.0
OR8H3	11384.0
OR4A47	11339.0
OR10W1	11327.0
OR4C16	11318.0
OR52N1	11258.0
OR5M3	11185.0
OR6X1	11097.0
OR5AP2	11090.0
CNGA4	11089.0
OR7C2	11074.0
OR2D3	11070.0
OR52M1	11050.0
OR10G7	11029.0
OR10J1	10968.0
OR10X1	10935.0
OR10A7	10927.0
OR1Q1	10896.0
OR5AN1	10887.0
OR9Q2	10885.0
OR4M1	10867.0
OR6Q1	10837.0
OR2G3	10670.0
OR14J1	10643.0
OR2AK2	10630.0
OR6C75	10603.0
OR13F1	10560.0
OR3A3	10543.0
OR52W1	10532.0
OR6F1	10520.0
OR51B6	10516.0
OR6V1	10462.0
OR2AG1	10374.0
OR10H1	10292.0
OR1I1	10274.0
OR13C8	10263.0
OR10J5	10235.0
OR10G4	10202.0
OR4C15	10194.0
OR8S1	10111.0
OR10V1	10109.0
OR14C36	9974.0
CNGB1	9965.0
OR5D18	9912.0
OR4E2	9752.0
OR1K1	9744.0
OR2M2	9732.0
OR10H5	9728.0
OR2T33	9673.0
OR51F1	9556.0
OR8U3	9526.0
OR5H2	9512.0
OR10C1	9497.0
OR8B4	9473.0
OR8J3	9209.0
OR1A2	9204.0
OR8A1	9153.0
OR2T8	9128.0
OR2L3	9122.0
OR5J2	9104.0
OR1B1	9036.0
OR52N2	9021.0
OR6C3	9007.0
OR10G9	8946.0
OR7A5	8942.0
OR2M3	8909.0
OR8D4	8872.0
OR6C74	8865.0
OR1E2	8772.0
OR2L2	8760.0
OR5H1	8719.0
OR8G1	8690.0
OR4D2	8647.0
OR2G6	8589.0
OR52B2	8586.0
OR10A4	8564.0
OR3A1	8484.0
OR5K2	8468.0
OR8K3	8451.0
OR5D13	8342.0
OR51I1	8276.0
OR4D10	8240.0
OR51B2	8223.0
OR4B1	8215.0
OR10A2	8188.0
OR4K2	8129.0
OR8D2	8059.0
OR52K1	7994.0
OR2V1	7972.0
OR52H1	7941.0
OR8H1	7821.0
OR4C45	7814.0
OR2AE1	7784.0
OR13C3	7741.0
OR56B1	7710.0
OR6N1	7706.0
OR2A2	7697.0
OR9Q1	7647.0
OR6B1	7623.0
OR10H2	7567.0
OR51L1	7565.0
OR56A1	7536.0
OR13C9	7179.0
OR7D2	7092.0
ANO2	7091.0
OR2H1	6965.0
OR1L3	6960.0
OR2M4	6948.0
OR2F2	6864.0
OR6K2	6848.0
OR5M10	6714.0
OR51B5	6581.0
OR2D2	6543.0
OR5B12	6502.0
OR14I1	6474.0
OR2L13	6470.0
OR51E2	6456.0
OR1L6	6436.0
OR7A17	6199.0
OR1J2	6160.0
OR7E24	6006.0
OR2T6	5971.0
OR56A4	5950.0
OR5P2	5600.0
OR13A1	5575.0
RTP1	5531.0
OR9G1	5285.5
OR9G9	5285.5
OR52A1	4945.0
OR4A15	4937.0
OR2T11	4887.0
OR2AG2	4876.0
OR6C4	4713.0
OR2C1	4695.0
OR9A4	4657.0
OR6C70	4616.0
OR12D3	4467.0
OR7G2	4420.0
OR8K5	4393.0
OR4F6	3861.0
EBF1	3745.0
OR8G5	3627.0
OR5C1	3560.0
REEP1	3254.0
OR1N2	3206.0
OR2F1	3035.0
OR5L2	3012.0
OR10H4	2992.0
OR10A6	2686.0
GNG13	2555.0
OR52J3	2519.0
OR2A5	2442.0
OR10AG1	2373.0
OR51I2	2268.0
OR52K2	2232.0
OR51M1	1952.0
OR5A2	1800.0
OR2T1	1361.0
OR8K1	1279.0
OR6M1	1227.0
OR6C1	1206.0
OR7D4	1064.0
OR6B3	975.0
OR2Z1	956.0
OR56A3	708.0
OR1S2	705.0
OR10Q1	659.0
OR5V1	255.0
OR1A1	15.0
OR8I2	12.0
OR4X2	-111.0
OR5AR1	-290.0
OR5B2	-303.0
OR1S1	-518.0
OR5D14	-718.0
OR51B4	-733.0
OR2B11	-968.0
GNAL	-1014.0
OR5A1	-1019.0
OR11H6	-1033.0
OR51A2	-1501.0
OR1D2	-1521.0
OR5M11	-1541.0
OR10H3	-1604.0
OR52B6	-1810.0
OR4S1	-1938.0
OR8U8	-2094.0
OR5B17	-2125.0
OR6C2	-2165.0
OR4X1	-2451.0
OR5B21	-2503.0
OR5L1	-2518.0
OR2W3	-2679.0
OR9A2	-2697.0
OR6T1	-2715.0
OR13D1	-2773.0
OR5W2	-2808.0
OR12D2	-2881.0
OR1L1	-2973.0
OR7G3	-3173.0
OR51A7	-3195.0
OR5M9	-3208.0
OR4A5	-3446.0
OR2C3	-3573.0
OR4K15	-3780.0
OR1C1	-3829.0
OR10G2	-3960.0
OR2A12	-4134.0
OR5K4	-4206.0
OR13G1	-4309.0
OR4F15	-4356.0
OR11G2	-4379.0
OR4K5	-4479.0
OR4D1	-4490.0
OR52E8	-4578.0
LDB1	-4619.0
OR1E1	-4660.0
OR2AP1	-4709.0
OR11A1	-4872.0
OR10K1	-4874.0
GNB1	-4992.0
OR4D11	-5146.0
OR4A16	-5257.0
OR4K13	-5384.0
OR2W1	-5495.0
OR5F1	-5559.0
OR4K17	-5662.0
ADCY3	-5699.0
LHX2	-5769.0
OR2A14	-5883.0
OR10P1	-6157.0
OR8D1	-6275.0
OR2T27	-6334.0
OR10A5	-6369.0
OR9I1	-6378.0
OR6C76	-6384.0
OR3A2	-6585.0
OR5AC2	-6636.0
OR4K14	-6641.0
OR5D16	-6755.0
OR52I2	-6808.0
OR9G4	-6975.0
OR2K2	-6998.0
OR8B2	-7001.0
OR7A10	-7075.0
OR4K1	-7081.0
OR4D6	-7239.0
OR2J2	-7285.0
OR5H6	-7372.0
OR11L1	-7376.0
OR1L4	-7378.0
OR7C1	-7398.0
OR4C46	-7485.0
OR10G8	-7539.0
OR5I1	-7545.0
OR8U1	-7691.0
OR6A2	-7732.0
OR11H4	-7827.0
OR5P3	-7886.0
OR2AT4	-7945.0
OR4C12	-7994.0
OR51F2	-8088.0
OR4D5	-8090.0
OR2B6	-8123.0
OR1M1	-8158.0
OR52L1	-8159.0
OR5AS1	-8257.0
OR5T3	-8281.0
OR52D1	-8337.0
OR6K6	-8455.0
OR6C68	-8536.0
OR2T4	-8544.0
OR6N2	-8563.0
OR2V2	-8587.0
OR6Y1	-8610.0
OR10AD1	-8656.0
OR14A16	-8686.0
OR52A5	-8695.0
OR13C2	-8704.0
OR6B2	-8707.0
OR5K1	-8732.0
OR5B3	-8733.0
OR8J1	-8746.0
OR5T1	-8820.0
OR5M8	-8868.0
OR6P1	-8909.0
OR8B12	-8951.0
OR2G2	-8969.0
OR2L5	-9028.0
OR4C6	-9099.0
OR5M1	-9114.0
OR7G1	-9122.0
OR6S1	-9179.0
OR2M7	-9192.0
OR10T2	-9194.0
OR2B3	-9199.0
OR4C3	-9213.0
OR4L1	-9217.0
OR2T12	-9266.0
OR4N5	-9285.0
OR2B2	-9291.0
OR2M5	-9349.0
OR1J1	-9398.0
OR5H15	-9436.0
OR52I1	-9441.0
OR6C6	-9447.0
OR5T2	-9473.0
OR4N2	-9510.0
OR5K3	-9595.0

---

REACTOME_G_ALPHA_I_SIGNALLING_EVENTS

REACTOME_G_ALPHA_I_SIGNALLING_EVENTS

	707
set	REACTOME_G_ALPHA_I_SIGNALLING_EVENTS
setSize	304
pANOVA	0.00101
s.dist	-0.11
p.adjustANOVA	0.0682

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CCL4	-9579
TAS2R43	-9559
P2RY13	-9357
RXFP4	-9345
GRK2	-9290
GNG8	-9227
RGS10	-9181
GALR3	-9160
TAS2R60	-9092
CCL19	-9066
TAS2R13	-8946
RLN3	-8916
ACKR3	-8890
DRD4	-8865
RGS21	-8837
GNAT1	-8827
ANXA1	-8752
CX3CR1	-8671
C3AR1	-8646
S1PR5	-8640

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CCL4	-9579
TAS2R43	-9559
P2RY13	-9357
RXFP4	-9345
GRK2	-9290
GNG8	-9227
RGS10	-9181
GALR3	-9160
TAS2R60	-9092
CCL19	-9066
TAS2R13	-8946
RLN3	-8916
ACKR3	-8890
DRD4	-8865
RGS21	-8837
GNAT1	-8827
ANXA1	-8752
CX3CR1	-8671
C3AR1	-8646
S1PR5	-8640
RGS14	-8639
TAS2R14	-8620
TAS2R10	-8608
TAS2R41	-8434
CCL1	-8369
CXCL11	-8326
CCR9	-8204
CCL25	-8149
P2RY12	-8136
GNG11	-8031
ADRA2B	-8016
APLNR	-7900
GPR31	-7893
PPP2CB	-7833
HTR1B	-7773
NPB	-7694
PPP1R1B	-7632
TAS1R3	-7588
SAA1	-7544
GNG2	-7528
GPR18	-7507
CCR4	-7487
POMC	-7482
NMUR1	-7471
CORT	-7254
GNB4	-7149
GPSM1	-7124
PDYN	-7017
PRKACG	-6896
PRKACB	-6812
PPBP	-6718
RGS4	-6484
PPP3CC	-6471
NPY5R	-6433
OXGR1	-6329
TAS2R3	-6283
TAS2R38	-6241
TAS2R42	-6225
TAS2R1	-6100
CXCR2	-6098
CALM1	-6055
RGS17	-6026
HRH4	-6015
OXER1	-5958
NBEA	-5776
ADCY3	-5699
TAS2R31	-5692
P2RY14	-5671
CCR8	-5601
PCP2	-5567
SST	-5540
OPN5	-5523
GRM7	-5422
TAS2R39	-5416
TAS2R50	-5370
GPR183	-5366
GALR2	-5323
RRH	-5200
ADCY7	-5111
PDE1B	-5018
GNB1	-4992
RGS9	-4964
TAS2R40	-4953
ITPR1	-4828
AHCYL1	-4817
GNB3	-4659
CCR10	-4519
GNG3	-4493
PDE4C	-4451
PLA2G4A	-4415
LPAR2	-4412
S1PR2	-4387
RXFP3	-4365
PLCB2	-4301
PENK	-4250
PSAP	-4188
TAS2R7	-4113
GABBR1	-4082
GNA14	-3794
GNAQ	-3714
PDE1C	-3646
ADRA2A	-3567
GNB5	-3516
GNG7	-3459
GNG4	-3344
NPBWR2	-3305
TAS2R9	-3287
PDE1A	-3100
PRKAR2B	-2948
TAS2R8	-2901
PYY	-2885
GNA15	-2817
PRKCD	-2784
ADCY9	-2758
NMUR2	-2716
SSTR5	-2658
MAPK1	-2642
RGS13	-2602
OPRD1	-2577
PTGER3	-2543
PPP2CA	-2522
PRKACA	-2469
MTNR1A	-2466
CHRM4	-2345
CCL28	-2262
OPN1SW	-2207
HEBP1	-2057
MCHR2	-2033
RGS3	-1926
ADCY8	-1894
NPBWR1	-1776
CXCL1	-1482
GPSM2	-1420
GNB2	-1313
CAMKK1	-1226
CCL23	-1093
PDE4A	-1071
OPRL1	-1025
GNAL	-1014
ADCY6	-982
PLCB1	-930
OPRK1	-892
LPAR5	-801
PPP1CA	-742
PTGDR2	-730
GPER1	-684
FPR1	-557
GNAT3	-553
PPP3CA	-552
SSTR1	-459
PPP3R1	-435
PLCB3	-381
GRM3	-370
PDE4B	-338
DRD3	-328
RGS18	-304
RGS20	-185
HCAR2	-125
OPN3	-98
CXCL6	-38
ITPR2	115
PNOC	131
RGS5	154
TAS2R19	232
SRC	374
CXCL9	423
CXCL16	434
CAMK2D	480
SUCNR1	636
PMCH	751
PRKAR1A	781
GRM2	818
OPRM1	971
APP	1001
SSTR4	1065
HTR1E	1068
SSTR3	1070
CASR	1106
PRKCG	1271
NMU	1272
GNA11	1321
S1PR3	1358
CAMKK2	1375
CCL13	1380
RGS16	1381
CAMK2G	1402
PPP3CB	1591
TAS2R4	1641
ITPR3	1682
PDE4D	1712
SSTR2	1790
PRKAR2A	1822
CXCR4	1870
TAS2R16	2044
GAL	2122
CX3CL1	2162
CAMK4	2199
HTR5A	2203
FPR3	2343
ADCY4	2412
GNG13	2555
RGR	2764
GNAI3	2785
CREB1	3039
PRKAR1B	3180
GRM8	3297
GNAI1	3400
GNGT1	3417
CXCL10	3493
C5	3528
HCAR1	3892
TAS2R46	4008
RGS7	4014
C5AR1	4117
PRKCA	4304
CCR3	4387
AGT	4495
GPSM3	4508
NPY2R	4538
C3	4811
ADCY2	5119
CXCL8	5133
PPY	5160
RGS19	5161
CHRM2	5206
FPR2	5380
RGS8	5383
PF4	5530
TAS1R2	5632
RGS22	5658
LPAR1	6123
MTNR1B	6264
GABBR2	6281
GPR37	6318
HTR1F	6322
GNAS	6345
RHO	6479
RGS11	6503
GNG5	6696
GRM6	6828
RGS1	6833
LPAR3	6867
CNR2	6939
GNGT2	7037
TAS1R1	7063
CXCL3	7389
PPP2R1B	7392
GALR1	7488
RGS6	7502
ADORA3	7589
RGS12	7606
CCR7	7671
CXCR5	7691
INSL5	7698
CXCL2	7749
PLCB4	8094
HTR1D	8140
CCR1	8254
ADORA1	8464
S1PR4	8495
GNAT2	8547
ADCY1	8656
TAS2R5	8657
CXCL13	8708
NPW	8796
KPNA2	8879
NPY	8903
PPP2R1A	9045
GRM4	9166
NPY1R	9270
CXCL12	9338
GNG12	9662
BDKRB2	9669
NMS	9671
CNR1	9682
GPR17	9687
GNAZ	9839
CCL16	9889
TAS2R20	9914
MCHR1	9989
ADRA2C	9991
GPR55	10045
CAMK2B	10096
CCR6	10314
GNG10	10359
RGSL1	10589
BDKRB1	10623
GNAI2	10680
CDK5	10685
GPR37L1	10749
CCR2	10929
ADCY5	10951
PPP2R5D	11025
CXCR1	11027
CAMK2A	11048
CXCL5	11432
TAS2R30	11468
CCL20	11499
CCR5	11646
KNG1	11806
CXCR6	11940
CCL21	12020
CCL5	12108
CCL27	12275

---

REACTOME_SIGNALING_BY_FGFR_IN_DISEASE

REACTOME_SIGNALING_BY_FGFR_IN_DISEASE

	56
set	REACTOME_SIGNALING_BY_FGFR_IN_DISEASE
setSize	62
pANOVA	0.00108
s.dist	-0.24
p.adjustANOVA	0.0682

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FGF17	-8899
FGF2	-8712
STAT3	-8571
FGF8	-8519
FGF23	-8241
CNTRL	-8135
POLR2J	-8074
FGF7	-7611
STAT5B	-7052
FRS2	-7024
PIK3R1	-6466
BCR	-6189
FGF5	-6062
GRB2	-5790
MYO18A	-5665
TRIM24	-5643
NRAS	-5634
POLR2E	-5528
CUX1	-5038
GTF2F2	-4815

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FGF17	-8899
FGF2	-8712
STAT3	-8571
FGF8	-8519
FGF23	-8241
CNTRL	-8135
POLR2J	-8074
FGF7	-7611
STAT5B	-7052
FRS2	-7024
PIK3R1	-6466
BCR	-6189
FGF5	-6062
GRB2	-5790
MYO18A	-5665
TRIM24	-5643
NRAS	-5634
POLR2E	-5528
CUX1	-5038
GTF2F2	-4815
FGFR1OP2	-4706
STAT5A	-4603
LRRFIP1	-4565
POLR2C	-4056
NCBP1	-4046
FGF18	-3774
GAB1	-2761
FGF20	-2754
FGF4	-2221
FGF9	-2184
POLR2K	-2038
CEP43	-1989
SOS1	-1653
BAG4	-1640
FGF10	-1587
ERLIN2	-1516
ZMYM2	-1173
HRAS	-327
FGFR4	57
POLR2L	160
POLR2I	261
PIK3CA	265
CPSF6	1521
STAT1	2001
POLR2H	2882
GAB2	2954
FGF3	3249
FGF22	3783
POLR2G	3785
POLR2A	3845
POLR2D	4651
FGF6	4751
FGF1	5299
FGFR1	5333
NCBP2	6104
POLR2F	6801
KRAS	7289
FGFR2	7583
GTF2F1	7678
POLR2B	7880
PLCG1	9968
FGFR3	10610

---

REACTOME_THE_CITRIC_ACID_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT

REACTOME_THE_CITRIC_ACID_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT

	104
set	REACTOME_THE_CITRIC_ACID_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT
setSize	159
pANOVA	0.00108
s.dist	0.15
p.adjustANOVA	0.0682

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NDUFB4	11611
COX8A	11577
NDUFA8	11172
ATP5MC1	11091
NDUFB5	11001
COX7A2L	10919
NDUFAF7	10605
ATP5MG	10591
ETFDH	10556
SURF1	10342
COX11	10259
MPC2	10168
PDHA2	10028
TIMMDC1	9931
ATP5F1D	9871
TMEM186	9826
NDUFA2	9811
NDUFA7	9777
ACO2	9725
ATP5MC3	9704

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
NDUFB4	11611
COX8A	11577
NDUFA8	11172
ATP5MC1	11091
NDUFB5	11001
COX7A2L	10919
NDUFAF7	10605
ATP5MG	10591
ETFDH	10556
SURF1	10342
COX11	10259
MPC2	10168
PDHA2	10028
TIMMDC1	9931
ATP5F1D	9871
TMEM186	9826
NDUFA2	9811
NDUFA7	9777
ACO2	9725
ATP5MC3	9704
CYCS	9672
ATP5PD	9666
NDUFS1	9637
NDUFB1	9620
COX6C	9611
NDUFB8	9461
NDUFA4	9431
FH	9295
SDHD	9040
NDUFA12	8994
COX6A1	8970
UQCRFS1	8789
IDH3B	8773
IDH2	8620
SDHB	8561
UQCR11	8501
NDUFS6	8440
VDAC1	8436
MPC1	8413
ATP5MF	8228
NDUFAF4	8213
NDUFA9	8189
PDPR	7614
ATP5PF	7576
SLC25A27	7517
PDP1	7331
PDK2	7304
COX20	7260
COQ10B	7184
NDUFA6	7102
MDH2	6991
DLST	6758
PDK4	6671
ATP5PO	6500
PDK1	6438
HAGH	6225
COX16	6220
NUBPL	6187
NNT	6070
NDUFAF3	5846
COX5B	5773
NDUFAF5	5713
NDUFA11	5705
SLC16A1	5610
UQCRB	5554
FAHD1	5481
NDUFS7	5437
NDUFB6	5222
ATP5F1C	4889
LDHA	4794
DLD	4793
LDHB	4412
NDUFA5	3724
NDUFV2	3647
NDUFB9	3615
TMEM126B	3606
GSTZ1	3453
SDHC	3355
PDP2	3343
BSG	3294
SUCLG2	3144
NDUFS5	3104
L2HGDH	3031
NDUFB7	2999
UQCRQ	2971
PM20D1	2905
ATP5PB	2689
NDUFAF6	2561
SUCLA2	2330
UQCR10	2244
LDHC	2136
D2HGDH	2075
ETFA	2053
SCO1	2049
ECSIT	1902
COQ10A	1847
ATP5ME	1785
NDUFAF1	1684
NDUFV3	1643
NDUFAF2	1629
COX4I1	1499
LDHAL6A	1445
NDUFB3	1440
UCP1	1432
NDUFV1	828
UCP2	529
COA1	509
COX14	445
NDUFS2	404
NDUFA10	233
ME3	81
DLAT	44
NDUFS4	-71
SLC16A3	-221
DMAC2L	-268
PDHX	-603
UQCRH	-643
NDUFA3	-826
NDUFB2	-902
ME2	-945
IDH3A	-1172
ATP5F1A	-1315
ADHFE1	-1438
OGDH	-1711
COX18	-1734
ME1	-1828
LDHAL6B	-1959
NDUFS3	-2009
TACO1	-2553
SUCLG1	-2734
COX19	-3009
COX7C	-3401
NDUFC1	-3564
GLO1	-3574
RXRA	-3755
COX5A	-3835
SDHA	-3838
LRPPRC	-3918
CYC1	-3998
ATP5F1B	-4094
NDUFB10	-4676
TRAP1	-4778
ACAD9	-4814
NDUFAB1	-5195
NDUFS8	-5304
NDUFC2	-5459
UQCRC2	-6390
UQCRC1	-7092
COX6B1	-7172
UCP3	-7175
SCO2	-7514
ETFB	-7901
ATP5MC2	-7944
PPARD	-8102
CS	-8310
ATP5F1E	-8373
SLC16A8	-8454
PDHB	-8537
NDUFA13	-8575

---

REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS

REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS

	1364
set	REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS
setSize	161
pANOVA	0.00156
s.dist	0.144
p.adjustANOVA	0.0947

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL10L	12167.0
RPS15A	11939.0
RPL7A	11625.0
PSMB11	11475.0
RPL15	11453.0
RPL12	11427.0
RPS13	11420.0
RPL30	11333.0
RPS2	11169.0
UBA52	11156.0
RPL13A	10972.5
RPS12	10945.0
RPL36AL	10700.5
RPL22L1	10372.0
RPS11	10361.0
RPL10A	10334.0
RPS21	10276.0
RPL37	10269.0
RPL28	10227.0
RPL9	10104.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL10L	12167.0
RPS15A	11939.0
RPL7A	11625.0
PSMB11	11475.0
RPL15	11453.0
RPL12	11427.0
RPS13	11420.0
RPL30	11333.0
RPS2	11169.0
UBA52	11156.0
RPL13A	10972.5
RPS12	10945.0
RPL36AL	10700.5
RPL22L1	10372.0
RPS11	10361.0
RPL10A	10334.0
RPS21	10276.0
RPL37	10269.0
RPL28	10227.0
RPL9	10104.0
RPL23A	9993.0
UBC	9929.0
RPS14	9890.0
RPL14	9804.0
RPS8	9803.0
PSMC3	9795.0
RPLP1	9750.0
RPS6	9691.0
PSMC1	9539.0
RPL27A	9530.0
RPL3	9494.0
RPS5	9380.0
RPS16	9206.0
RPLP0	9015.0
RPL8	8995.0
RPS7	8958.0
RPL26L1	8771.0
RPS10	8500.0
PSMB2	8481.0
PSMB9	8387.0
RPL21	8358.0
PSME2	8279.0
PSMD8	8061.0
ETF1	8051.0
ELOC	7851.0
PSMC6	7767.0
RPL29	7724.0
RPL13	7681.0
RPS18	7574.0
RPS28	7553.0
PSMB5	7505.0
SLIT1	7479.0
PSMB3	7215.0
EIF4A3	7076.0
RPL18	6982.0
RPL24	6818.0
RPS26	6403.0
PSMD13	6257.0
RPS29	6202.0
FAU	6182.0
NCBP2	6104.0
RNPS1	6016.0
RPL36	5777.0
RBM8A	5688.0
RPSA	5509.0
CUL2	5095.0
PSMD14	4844.0
PSMB6	4820.0
PSMC5	4808.0
RPL11	4720.0
RPS23	4694.0
MAGOHB	4342.0
RPS20	4325.0
PABPC1	4184.0
DAG1	3844.0
HOXA2	3774.0
RPS24	3750.0
ROBO3	3628.0
SEM1	3569.0
PSMB8	3437.0
RPS27A	3415.0
RPL23	3223.0
PSMA7	3056.0
RPS15	3030.0
RPS9	2957.0
ELOB	2851.0
RPS27	2734.0
PSMA3	2680.0
RPL35	2573.0
PSME3	2564.0
RPL26	2485.0
RPL37A	2197.0
PSMC4	2167.0
PSMA6	2004.0
PSMA4	1771.0
PSMC2	1501.0
RPL18A	1454.0
PSMB1	1426.0
RPS3	1293.0
PSMA2	1209.0
RPL7	1003.0
RPL22	817.0
PSMD3	478.0
RPL38	447.0
PSMD2	365.0
PSMB4	130.0
SLIT2	-127.0
PSMD5	-130.0
PSMD6	-426.0
RPL4	-477.0
LHX4	-561.0
RPS3A	-578.0
RPL6	-775.0
PSMD4	-820.0
ROBO2	-855.0
PSMD1	-859.0
MAGOH	-1401.0
RPL5	-1407.0
UBB	-1544.0
RPL3L	-1681.0
RPLP2	-1871.0
ISL1	-1954.0
CASC3	-2269.0
RPS27L	-2461.0
PSMA1	-2596.0
RPL35A	-2635.0
RPL32	-2777.0
PSMD9	-2789.0
UPF2	-3217.0
RPS19	-3548.0
PSMA5	-3601.0
PSMF1	-3809.0
PSMD7	-3845.0
ZSWIM8	-3897.0
NCBP1	-4046.0
RPL27	-4089.0
ROBO1	-4127.0
RPS25	-4512.0
RPL39L	-4522.0
LDB1	-4619.0
PSMD11	-4724.0
PSMB10	-4752.0
RPL34	-5135.0
PSMD12	-5677.0
LHX2	-5769.0
USP33	-6002.0
RPL19	-6199.0
RBX1	-6240.0
PSMB7	-6344.0
UPF3A	-6399.0
PSME1	-6518.0
LHX9	-6604.0
EIF4G1	-6670.0
GSPT1	-6923.0
PSME4	-7369.0
RPL41	-7598.0
PSMA8	-7628.0
RPL17	-7707.0
LHX3	-7913.0
MSI1	-8028.0
RPL31	-8083.0

---

REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION

REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION

	1193
set	REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION
setSize	250
pANOVA	0.00161
s.dist	-0.116
p.adjustANOVA	0.0947

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SELENOP	-9317
GNG8	-9227
FCER1G	-9221
GP1BA	-9058
APLP2	-9015
A1BG	-8960
SRGN	-8944
F2RL2	-8822
LCK	-8743
GP1BB	-8361
ACTN1	-8358
RAP1B	-8270
SPP2	-8253
P2RY12	-8136
ALB	-8122
CFD	-8091
GNG11	-8031
ADRA2B	-8016
MMRN1	-7983
STXBP3	-7968

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SELENOP	-9317
GNG8	-9227
FCER1G	-9221
GP1BA	-9058
APLP2	-9015
A1BG	-8960
SRGN	-8944
F2RL2	-8822
LCK	-8743
GP1BB	-8361
ACTN1	-8358
RAP1B	-8270
SPP2	-8253
P2RY12	-8136
ALB	-8122
CFD	-8091
GNG11	-8031
ADRA2B	-8016
MMRN1	-7983
STXBP3	-7968
IGF1	-7671
RHOB	-7636
ARRB2	-7590
GNG2	-7528
STXBP2	-7476
RASGRP2	-7275
GP5	-7154
GNB4	-7149
ECM1	-7114
GP9	-7090
RAC2	-6931
MPL	-6868
CSK	-6864
DAGLB	-6776
PPBP	-6718
CD36	-6515
DGKG	-6480
PIK3R1	-6466
WDR1	-6302
CDC42	-6295
PDPN	-6211
CALM1	-6055
F2RL3	-5978
DGKH	-5813
GRB2	-5790
RAC1	-5691
VEGFC	-5628
DGKE	-5589
FAM3C	-5546
APOA1	-5516
LCP2	-5403
TOR4A	-5364
SERPING1	-5089
GNB1	-4992
DGKZ	-4991
PTPN1	-4943
PDPK1	-4919
ITPR1	-4828
TGFB2	-4680
GNB3	-4659
APBB1IP	-4652
PRKCH	-4547
GNG3	-4493
QSOX1	-4453
CLEC3B	-4446
PLA2G4A	-4415
SERPINE1	-4246
PSAP	-4188
SOD1	-4161
TIMP3	-4008
GTPBP2	-3972
DGKA	-3874
F2	-3871
BCAR1	-3851
GNA14	-3794
CALU	-3788
GNAQ	-3714
SCCPDH	-3615
SCG3	-3596
ADRA2A	-3567
GNB5	-3516
TRPC6	-3460
GNG7	-3459
YWHAZ	-3448
RAP1A	-3445
GNG4	-3344
PTPN6	-3251
GNA12	-3205
SYK	-3183
GNA13	-3172
DGKD	-2947
ALDOA	-2920
VCL	-2878
ITGA2B	-2859
MGLL	-2842
F5	-2832
GNA15	-2817
PRKCD	-2784
TRPC3	-2694
MAPK1	-2642
PIK3CG	-2563
RARRES2	-2539
CLU	-2465
PRKCB	-2434
PHACTR2	-2408
NHLRC2	-2138
PECAM1	-2108
OLA1	-2102
SERPINA3	-2070
MAPK14	-1965
PRKCZ	-1656
SOS1	-1653
PIK3R2	-1452
FERMT3	-1338
GNB2	-1313
CRK	-1152
BRPF3	-1058
PROS1	-748
CD63	-609
SHC1	-599
GNAT3	-553
SELP	-514
VWF	-494
RASGRP1	-447
LAT	-371
PIK3CB	-320
PIK3R6	-226
RAF1	-132
PFN1	93
LHFPL2	97
ITPR2	115
PRKCQ	124
PIK3CA	265
RHOG	285
PPIA	302
SRC	374
STX4	524
TMX3	673
DGKB	792
ABCC4	823
ITGB3	876
CYRIB	917
LYN	942
FGB	954
VTI1B	977
CAP1	994
APP	1001
ABHD12	1016
TUBA4A	1089
PRKCG	1271
ENDOD1	1287
GNA11	1321
FYN	1368
TTN	1485
TRPC7	1503
PLEK	1514
ITPR3	1682
IGF2	1808
HRG	1842
MPIG6B	1846
PTK2	1917
TAGLN2	2005
PRKCE	2099
ACTN2	2109
VAV2	2223
GNG13	2555
CFL1	2658
COL1A1	2731
GNAI3	2785
PDGFB	2819
VAV3	2988
VEGFB	3049
MAPK3	3132
GNAI1	3400
GNGT1	3417
RAPGEF3	3522
CD109	3572
ARRB1	3626
P2RY1	3641
CHID1	3666
PCYOX1L	3697
PLCG2	3712
CYB5R1	3816
PDGFA	3935
PCDH7	4297
PRKCA	4304
ACTN4	4307
AKT1	4367
LY6G6F	4684
DGKQ	4703
TGFB1	4753
COL1A2	4840
CD9	5070
TLN1	5153
ORM1	5154
TBXA2R	5195
VAV1	5316
PIK3R3	5467
HSPA5	5469
PF4	5530
DAGLA	5719
CDC37L1	5743
EGF	6426
APOH	6561
GNG5	6696
F13A1	6705
TEX264	6934
GNGT2	7037
MANF	7206
CLEC1B	7348
PIK3R5	7410
PLG	7570
A2M	7658
F2R	7737
LEFTY2	7739
TF	7820
RAPGEF4	7846
FN1	8022
DGKI	8077
HGF	8166
RAB27B	8190
CTSW	8510
AHSG	8595
LGALS3BP	8682
PTPN11	8945
ISLR	9046
SPARC	9047
AAMP	9653
GNG12	9662
GP6	9723
ADRA2C	9991
THBS1	10146
THPO	10147
VEGFA	10223
FGA	10283
ANXA5	10343
GNG10	10359
TGFB3	10366
ITIH4	10596
GNAI2	10680
RHOA	10768
SERPINF2	10963
SERPINA4	11098
FGG	11386
HABP4	11399
ORM2	11474
ABHD6	11726
SERPINA1	11794
KNG1	11806
ITIH3	11832

---

REACTOME_PI_3K_CASCADE_FGFR4

REACTOME_PI_3K_CASCADE_FGFR4

	951
set	REACTOME_PI_3K_CASCADE_FGFR4
setSize	19
pANOVA	0.00174
s.dist	-0.415
p.adjustANOVA	0.0988

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FGF17	-8899
FGF2	-8712
FGF8	-8519
FGF23	-8241
KLB	-7682
FRS2	-7024
PIK3R1	-6466
GRB2	-5790
FGF19	-4358
FGF18	-3774
GAB1	-2761
FGF20	-2754
FGF4	-2221
FGF9	-2184
FGFR4	57
PIK3CA	265
FGF6	4751
FGF1	5299
PTPN11	8945

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FGF17	-8899
FGF2	-8712
FGF8	-8519
FGF23	-8241
KLB	-7682
FRS2	-7024
PIK3R1	-6466
GRB2	-5790
FGF19	-4358
FGF18	-3774
GAB1	-2761
FGF20	-2754
FGF4	-2221
FGF9	-2184
FGFR4	57
PIK3CA	265
FGF6	4751
FGF1	5299
PTPN11	8945

---

REACTOME_SARS_COV_2_INFECTION

REACTOME_SARS_COV_2_INFECTION

	1553
set	REACTOME_SARS_COV_2_INFECTION
setSize	281
pANOVA	0.00257
s.dist	0.104
p.adjustANOVA	0.141

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IFNB1	12214.0
RPS15A	11939.0
NOD2	11840.0
HLA-B	11688.0
CHMP2A	11573.0
MASP1	11478.0
NUP88	11439.0
RPS13	11420.0
CHMP4A	11381.0
RPS2	11169.0
UBA52	11156.0
IFNA21	11080.0
RPS12	10945.0
POM121C	10915.0
SNRPF	10863.0
RPN2	10781.0
MGAT2	10700.5
TUFM	10496.0
TRAF6	10486.0
TKFC	10399.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IFNB1	12214.0
RPS15A	11939.0
NOD2	11840.0
HLA-B	11688.0
CHMP2A	11573.0
MASP1	11478.0
NUP88	11439.0
RPS13	11420.0
CHMP4A	11381.0
RPS2	11169.0
UBA52	11156.0
IFNA21	11080.0
RPS12	10945.0
POM121C	10915.0
SNRPF	10863.0
RPN2	10781.0
MGAT2	10700.5
TUFM	10496.0
TRAF6	10486.0
TKFC	10399.0
RPS11	10361.0
RPS21	10276.0
ANO7	10272.0
ANO1	10112.0
UBC	9929.0
RPS14	9890.0
RPS8	9803.0
NUP42	9786.0
ZDHHC8	9743.0
RPS6	9691.0
PRKCSH	9605.0
ISCU	9591.0
IRAK2	9569.0
STT3A	9505.0
SDC1	9427.0
RPS5	9380.0
RPS16	9206.0
VCP	9162.0
TRIM4	9118.0
SNRPD2	9094.0
SIKE1	9051.0
RPS7	8958.0
PTPN11	8945.0
KPNA2	8879.0
ZDHHC5	8870.0
HSP90AA1	8781.0
MBL2	8748.0
NRP1	8663.0
MASP2	8651.0
NUP43	8536.0
RPS10	8500.0
NUP62	8463.0
RIPK2	8428.0
HSP90AB1	8403.0
NUP107	8380.0
ANO4	8354.0
IFIH1	8321.0
HLA-C	8317.0
IKBKE	8307.0
NUP133	8148.0
PARP8	8143.0
TOMM70	8121.0
YWHAE	7894.0
B2M	7779.0
SNRPB	7733.0
AGRN	7638.0
ANO8	7626.0
SRPK1	7610.0
RPS18	7574.0
RPS28	7553.0
SNRPG	7349.0
NUP155	7250.0
SFTPD	7197.0
CSNK1A1	7131.0
ANO2	7091.0
ZDHHC20	7090.0
SNRPD1	7039.0
HAVCR1	7034.0
GEMIN5	6943.0
TPR	6866.0
DDX20	6557.0
PIK3R4	6524.0
SNRPD3	6442.0
DDX5	6421.0
RPS26	6403.0
CHMP6	6349.0
SEC24B	6280.0
CNBP	6240.0
GPC1	6227.0
RPS29	6202.0
FAU	6182.0
MGAT1	6137.0
CHMP3	5819.0
IRF3	5790.0
HLA-A	5686.0
CANX	5676.0
AKT2	5582.0
RPSA	5509.0
NUP37	5379.0
SEC24A	5255.0
NUP93	5225.0
NUP188	5176.0
CAV1	5106.0
RPN1	5072.0
NUP160	4948.0
ST3GAL3	4842.0
IFNA16	4779.0
ST3GAL4	4724.0
RPS23	4694.0
GPC6	4664.0
GEMIN6	4536.0
NUP35	4415.0
AKT1	4367.0
PARP14	4364.0
RPS20	4325.0
MAN2A1	4251.0
MGAT4C	4238.0
IFNA13	4135.0
YWHAB	4065.0
NUP205	3947.0
IL17A	3888.0
SEC13	3809.0
RPS24	3750.0
UBE2I	3720.0
UBE2V1	3719.0
RANBP2	3650.0
MGAT4B	3644.0
ATG14	3639.0
TBK1	3593.0
IFNA6	3495.0
IL17RC	3471.0
RPS27A	3415.0
VPS16	3390.0
EDEM2	3381.0
ZDHHC3	3375.0
ISG15	3326.0
IL17F	3301.0
IL17RA	3286.0
NUP54	3207.0
DAD1	3156.0
VPS41	3094.0
RPS15	3030.0
RPS9	2957.0
LARP1	2878.0
RPS27	2734.0
NUP98	2548.0
CHMP2B	2534.0
CHMP7	2492.0
ZCRB1	2465.0
ZDHHC2	2398.0
YWHAH	2374.0
GPC5	2318.0
PARP9	2308.0
IKBKB	2200.0
PATJ	2115.0
STAT1	2001.0
VHL	1925.0
SEH1L	1872.0
GSK3A	1862.0
RIGI	1713.0
ANO6	1574.0
ANO10	1525.0
ST3GAL2	1522.0
GJA1	1465.0
TYK2	1442.0
RPS3	1293.0
VPS45	1275.0
ANO3	1039.0
IFNAR1	1035.0
UBE2N	980.0
NDC1	964.0
HLA-F	908.0
VPS11	861.0
SRPK2	785.0
IRF7	736.0
STAT2	725.0
PRMT1	664.0
HLA-E	647.0
RNF135	580.0
TMPRSS2	554.0
GSK3B	349.0
CTSL	67.0
SMN1	64.5
SMN2	64.5
TJP1	-13.0
FURIN	-33.0
TRIM25	-73.0
FUT8	-103.0
SUMO1	-158.0
JAK1	-159.0
YWHAQ	-274.0
DDOST	-293.0
SDC4	-439.0
SEC24D	-442.0
RPS3A	-578.0
RB1	-698.0
CHUK	-758.0
CHMP4B	-1010.0
VPS18	-1041.0
BECN1	-1114.0
IFNA2	-1244.0
MAVS	-1327.0
SAR1B	-1427.0
PARP4	-1519.0
UBB	-1544.0
MGAT4A	-1570.0
TUSC3	-1763.0
VPS33A	-1918.0
GOLGA7	-2066.0
VPS39	-2229.0
SDC2	-2244.0
TLR2	-2299.0
ZDHHC11	-2363.0
GEMIN7	-2406.0
RPS27L	-2461.0
AAAS	-2517.0
NLRP12	-2548.0
ST6GALNAC2	-2629.0
GALNT1	-2711.0
UVRAG	-2872.0
ST6GALNAC3	-2983.0
MAP1LC3B	-3004.0
G3BP2	-3181.0
PTPN6	-3251.0
HSPG2	-3402.0
SEC23A	-3439.0
YWHAZ	-3448.0
YWHAG	-3454.0
IFNA1	-3508.0
IFNA7	-3509.0
RPS19	-3548.0
TAB2	-3591.0
TRAF3	-3655.0
ANO9	-3689.0
AKT3	-3729.0
ST3GAL1	-3789.0
SDC3	-3850.0
SEC24C	-3912.0
NUP153	-3940.0
NUP210	-3969.0
NUP50	-3978.0
STING1	-4068.0
ST6GAL1	-4070.0
MAN1B1	-4312.0
RPS25	-4512.0
MOGS	-4723.0
ANO5	-4824.0
PDPK1	-4919.0
TAB1	-4920.0
MAP3K7	-4923.0
PARP16	-5047.0
CHMP4C	-5074.0
IFNAR2	-5172.0
NUP214	-5218.0
GEMIN2	-5476.0
HLA-G	-5558.0
PIK3C3	-5673.0
NUP58	-5770.0
IFNA14	-5915.0
G3BP1	-6034.0
GEMIN4	-6343.0
GANAB	-6525.0
PALS1	-6618.0
NOD1	-6794.0
NLRP3	-6924.0
RAE1	-6991.0
CREBBP	-7240.0
VPS33B	-7276.0
MGAT5	-7307.0
NUP85	-7391.0
CRB3	-7440.0
IFNA5	-7447.0
SNRPE	-7549.0
PARP6	-7585.0
IFNA8	-8008.0
GPC2	-8033.0
TLR1	-8073.0
PARP10	-8211.0
POM121	-8428.0
SFN	-8545.0
ST6GALNAC4	-8842.0

---

REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS

REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS

	179
set	REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS
setSize	111
pANOVA	0.00316
s.dist	0.162
p.adjustANOVA	0.167

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NDUFB4	11611
COX8A	11577
NDUFA8	11172
ATP5MC1	11091
NDUFB5	11001
COX7A2L	10919
NDUFAF7	10605
ATP5MG	10591
ETFDH	10556
SURF1	10342
COX11	10259
TIMMDC1	9931
ATP5F1D	9871
TMEM186	9826
NDUFA2	9811
NDUFA7	9777
ATP5MC3	9704
CYCS	9672
ATP5PD	9666
NDUFS1	9637

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
NDUFB4	11611
COX8A	11577
NDUFA8	11172
ATP5MC1	11091
NDUFB5	11001
COX7A2L	10919
NDUFAF7	10605
ATP5MG	10591
ETFDH	10556
SURF1	10342
COX11	10259
TIMMDC1	9931
ATP5F1D	9871
TMEM186	9826
NDUFA2	9811
NDUFA7	9777
ATP5MC3	9704
CYCS	9672
ATP5PD	9666
NDUFS1	9637
NDUFB1	9620
COX6C	9611
NDUFB8	9461
NDUFA4	9431
SDHD	9040
NDUFA12	8994
COX6A1	8970
UQCRFS1	8789
SDHB	8561
UQCR11	8501
NDUFS6	8440
ATP5MF	8228
NDUFAF4	8213
NDUFA9	8189
ATP5PF	7576
SLC25A27	7517
COX20	7260
COQ10B	7184
NDUFA6	7102
ATP5PO	6500
COX16	6220
NUBPL	6187
NDUFAF3	5846
COX5B	5773
NDUFAF5	5713
NDUFA11	5705
UQCRB	5554
NDUFS7	5437
NDUFB6	5222
ATP5F1C	4889
NDUFA5	3724
NDUFV2	3647
NDUFB9	3615
TMEM126B	3606
SDHC	3355
NDUFS5	3104
NDUFB7	2999
UQCRQ	2971
PM20D1	2905
ATP5PB	2689
NDUFAF6	2561
UQCR10	2244
ETFA	2053
SCO1	2049
ECSIT	1902
COQ10A	1847
ATP5ME	1785
NDUFAF1	1684
NDUFV3	1643
NDUFAF2	1629
COX4I1	1499
NDUFB3	1440
UCP1	1432
NDUFV1	828
UCP2	529
COA1	509
COX14	445
NDUFS2	404
NDUFA10	233
NDUFS4	-71
DMAC2L	-268
UQCRH	-643
NDUFA3	-826
NDUFB2	-902
ATP5F1A	-1315
COX18	-1734
NDUFS3	-2009
TACO1	-2553
COX19	-3009
COX7C	-3401
NDUFC1	-3564
COX5A	-3835
SDHA	-3838
LRPPRC	-3918
CYC1	-3998
ATP5F1B	-4094
NDUFB10	-4676
TRAP1	-4778
ACAD9	-4814
NDUFAB1	-5195
NDUFS8	-5304
NDUFC2	-5459
UQCRC2	-6390
UQCRC1	-7092
COX6B1	-7172
UCP3	-7175
SCO2	-7514
ETFB	-7901
ATP5MC2	-7944
ATP5F1E	-8373
NDUFA13	-8575

---

REACTOME_SHC_MEDIATED_CASCADE_FGFR4

REACTOME_SHC_MEDIATED_CASCADE_FGFR4

	950
set	REACTOME_SHC_MEDIATED_CASCADE_FGFR4
setSize	19
pANOVA	0.00362
s.dist	-0.386
p.adjustANOVA	0.186

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FGF17	-8899
FGF2	-8712
FGF8	-8519
FGF23	-8241
KLB	-7682
GRB2	-5790
NRAS	-5634
FGF19	-4358
FGF18	-3774
FGF20	-2754
FGF4	-2221
FGF9	-2184
SOS1	-1653
SHC1	-599
HRAS	-327
FGFR4	57
FGF6	4751
FGF1	5299
KRAS	7289

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FGF17	-8899
FGF2	-8712
FGF8	-8519
FGF23	-8241
KLB	-7682
GRB2	-5790
NRAS	-5634
FGF19	-4358
FGF18	-3774
FGF20	-2754
FGF4	-2221
FGF9	-2184
SOS1	-1653
SHC1	-599
HRAS	-327
FGFR4	57
FGF6	4751
FGF1	5299
KRAS	7289

---

REACTOME_LEISHMANIA_INFECTION

REACTOME_LEISHMANIA_INFECTION

	1509
set	REACTOME_LEISHMANIA_INFECTION
setSize	156
pANOVA	0.00385
s.dist	-0.134
p.adjustANOVA	0.191

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GNG8	-9227
CTSG	-9117
IL1B	-8982
MYO1C	-8843
C3AR1	-8646
IL10	-8617
PYCARD	-8452
TXNIP	-8229
NCKAP1L	-8141
GNG11	-8031
DVL3	-7946
MYH9	-7715
ACTG1	-7690
GNG2	-7528
CD163	-7486
CYBA	-7455
CD247	-7156
GNB4	-7149
NLRP3	-6924
PRKACG	-6896

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GNG8	-9227
CTSG	-9117
IL1B	-8982
MYO1C	-8843
C3AR1	-8646
IL10	-8617
PYCARD	-8452
TXNIP	-8229
NCKAP1L	-8141
GNG11	-8031
DVL3	-7946
MYH9	-7715
ACTG1	-7690
GNG2	-7528
CD163	-7486
CYBA	-7455
CD247	-7156
GNB4	-7149
NLRP3	-6924
PRKACG	-6896
PRKACB	-6812
RHBDF2	-6626
CDC42	-6295
P2RX7	-6264
CALM1	-6055
GRB2	-5790
ABL1	-5751
ADCY3	-5699
RAC1	-5691
ADCY7	-5111
ELMO1	-5063
MAPK8	-5008
GNB1	-4992
NOXA1	-4968
ITPR1	-4828
AHCYL1	-4817
GNB3	-4659
ARPC1B	-4558
GNG3	-4493
ELMO2	-4335
MYH2	-4332
CYFIP2	-4231
CASP1	-3884
WASF2	-3859
FZD7	-3781
IL1A	-3745
WIPF3	-3717
GNB5	-3516
GNG7	-3459
GNG4	-3344
NOXO1	-3321
ACTR3	-3231
SYK	-3183
PRKAR2B	-2948
WIPF2	-2919
ADCY9	-2758
DPEP2	-2738
ARPC2	-2645
MAPK1	-2642
WASF3	-2575
FGR	-2506
PRKACA	-2469
ADAM17	-2450
MYO9B	-2199
RELA	-2013
MAPK14	-1965
ADCY8	-1894
ACTB	-1798
CYSLTR2	-1603
NT5E	-1518
ARPC3	-1411
NFKB1	-1326
WASL	-1316
GNB2	-1313
CRK	-1152
IL18	-1012
ADCY6	-982
MYO5A	-767
ABI2	-667
ENTPD5	-647
GNAT3	-553
ARPC4	-175
FURIN	-33
GGT1	-6
ITPR2	115
DVL1	135
JUN	242
SRC	374
PRKAR1A	781
MEFV	919
LYN	942
APP	1001
ADORA2B	1129
SUGT1	1327
FYN	1368
CD3G	1411
ARPC5	1523
HMOX1	1654
ITPR3	1682
PRKAR2A	1822
PTK2	1917
PLK2	2027
NCK1	2121
VAV2	2223
YES1	2253
WIPF1	2383
ADCY4	2412
P2RX4	2505
GNG13	2555
GNAI3	2785
ARPC1A	2828
VAV3	2988
CREB1	3039
MAPK3	3132
PRKAR1B	3180
DPEP1	3395
GNAI1	3400
GNGT1	3417
NFKB2	3472
PLCG2	3712
MYO10	4266
C3	4811
ADCY2	5119
FCGR2A	5124
VAV1	5316
HCK	5428
GSDMD	5489
ABI1	5689
PSTPIP1	5690
GNAS	6345
ENTPD1	6599
BAIAP2	6616
GNG5	6696
GNGT2	7037
DVL2	7068
DOCK1	7220
NCKAP1	7471
CYFIP1	7629
IL6	7669
TXN	8360
HSP90AB1	8403
WNT5A	8544
ADCY1	8656
FCGR3A	8706
NCKIPSD	8981
ACTR2	9244
BRK1	9391
GNG12	9662
GNAZ	9839
PLCG1	9968
GNG10	10359
GNAI2	10680
ADCY5	10951
WASF1	11030
GGT5	11983
DPEP3	12158

---

REACTOME_CHAPERONE_MEDIATED_AUTOPHAGY

REACTOME_CHAPERONE_MEDIATED_AUTOPHAGY

	1469
set	REACTOME_CHAPERONE_MEDIATED_AUTOPHAGY
setSize	20
pANOVA	0.00424
s.dist	0.369
p.adjustANOVA	0.205

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GFAP	11857
RNASE1	11402
UBA52	11156
HBB	10875
EEF1A1	9945
UBC	9929
HSP90AA1	8781
HSP90AB1	8403
ARL13B	7417
CETN1	6488
HSPA8	5687
PARK7	5100
PLIN2	3427
RPS27A	3415
PLIN3	2134
IFT88	330
VIM	41
UBB	-1544
PCNT	-2609
CFTR	-3044

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GFAP	11857
RNASE1	11402
UBA52	11156
HBB	10875
EEF1A1	9945
UBC	9929
HSP90AA1	8781
HSP90AB1	8403
ARL13B	7417
CETN1	6488
HSPA8	5687
PARK7	5100
PLIN2	3427
RPS27A	3415
PLIN3	2134
IFT88	330
VIM	41
UBB	-1544
PCNT	-2609
CFTR	-3044

---

REACTOME_HCMV_LATE_EVENTS

REACTOME_HCMV_LATE_EVENTS

	1466
set	REACTOME_HCMV_LATE_EVENTS
setSize	110
pANOVA	0.00441
s.dist	0.157
p.adjustANOVA	0.207

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2BC26	11690
H2AC25	11656
MVB12A	11582
CHMP2A	11573
NUP88	11439
CHMP4A	11381
H2BC1	11371
H3C10	11238
H2AC11	10966
POM121C	10915
H2AC20	10845
H2AC16	10668
H4C3	10651
H2AC8	10550
H2BC8	10339
H2AC1	10251
NUP42	9786
H2BC21	9545
H2BC15	9507
CEBPD	9432

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2BC26	11690.0
H2AC25	11656.0
MVB12A	11582.0
CHMP2A	11573.0
NUP88	11439.0
CHMP4A	11381.0
H2BC1	11371.0
H3C10	11238.0
H2AC11	10966.0
POM121C	10915.0
H2AC20	10845.0
H2AC16	10668.0
H4C3	10651.0
H2AC8	10550.0
H2BC8	10339.0
H2AC1	10251.0
NUP42	9786.0
H2BC21	9545.0
H2BC15	9507.0
CEBPD	9432.0
H4C5	8846.0
H2AC12	8653.0
NUP43	8536.0
H2BC11	8467.0
NUP62	8463.0
H2AC15	8445.0
NUP107	8380.0
NUP133	8148.0
H2AC21	8024.0
H3C11	8004.0
H2AC13	7833.0
H3C2	7722.0
TSG101	7632.0
VPS37A	7458.0
H2AC6	7431.0
CHMP1A	7404.0
NUP155	7250.0
SNF8	7051.0
TPR	6866.0
H4C11	6636.0
H4C12	6590.0
VPS36	6483.0
CHMP6	6349.0
CHMP3	5819.0
H4C16	5792.0
NUP37	5379.0
NUP93	5225.0
H4C8	5220.0
NUP188	5176.0
H4C13	5058.0
H3C1	5045.0
H2AC7	5028.5
H2BC7	5028.5
NUP160	4948.0
VPS37D	4858.0
H2AC4	4799.0
NUP35	4415.0
H2BC9	4207.5
H3C7	4207.5
VPS28	4104.0
H2BC13	3995.0
H2BC17	3952.0
NUP205	3947.0
SEC13	3809.0
RANBP2	3650.0
NUP54	3207.0
H4C4	3167.0
H3C4	3114.0
H4C2	2860.0
HNRNPK	2765.0
NUP98	2548.0
CHMP2B	2534.0
CHMP7	2492.0
H2BC4	1896.0
SEH1L	1872.0
H2BC5	1091.0
NDC1	964.0
H3C12	-520.0
CHMP4B	-1010.0
H2AC17	-1125.0
VPS4A	-1574.0
MVB12B	-2340.0
AAAS	-2517.0
H2BC12	-3037.0
H4C1	-3415.0
H2BC10	-3641.0
NUP153	-3940.0
NUP210	-3969.0
NUP50	-3978.0
H4C6	-4389.0
VPS25	-4672.0
CHMP4C	-5074.0
NUP214	-5218.0
NUP58	-5770.0
H2AC18	-5862.5
H2AC19	-5862.5
H2BC6	-6385.0
RAE1	-6991.0
VPS37B	-7356.0
NUP85	-7391.0
H3C8	-7667.0
UBAP1	-8128.0
VPS37C	-8179.0
H4C9	-8234.0
POM121	-8428.0
H2BC14	-8430.0
H2AC14	-8665.0
H3C3	-8949.0
H2BC3	-9038.0
H3C6	-9347.0

---

REACTOME_SENSORY_PERCEPTION_OF_TASTE

REACTOME_SENSORY_PERCEPTION_OF_TASTE

	1586
set	REACTOME_SENSORY_PERCEPTION_OF_TASTE
setSize	47
pANOVA	0.005
s.dist	-0.237
p.adjustANOVA	0.226

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TAS2R43	-9559
OTOP1	-9189
TAS2R13	-8946
TAS2R14	-8620
TAS2R10	-8608
TAS2R41	-8434
TAS1R3	-7588
SCN4B	-7494
TAS2R3	-6283
TAS2R38	-6241
TAS2R1	-6100
TAS2R31	-5692
TAS2R39	-5416
TAS2R50	-5370
SCN1B	-5097
GNB1	-4992
TAS2R40	-4953
GNB3	-4659
PLCB2	-4301
TAS2R7	-4113

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TAS2R43	-9559
OTOP1	-9189
TAS2R13	-8946
TAS2R14	-8620
TAS2R10	-8608
TAS2R41	-8434
TAS1R3	-7588
SCN4B	-7494
TAS2R3	-6283
TAS2R38	-6241
TAS2R1	-6100
TAS2R31	-5692
TAS2R39	-5416
TAS2R50	-5370
SCN1B	-5097
GNB1	-4992
TAS2R40	-4953
GNB3	-4659
PLCB2	-4301
TAS2R7	-4113
KCNJ2	-4066
SCN2A	-3994
SCNN1D	-3289
TAS2R8	-2901
SCN3A	-2242
GNAT3	-553
SCNN1G	-1
SCN9A	649
TAS2R4	1641
ITPR3	1682
SCN2B	1875
TAS2R16	2044
CALHM1	2058
GNG13	2555
CALHM3	2717
SCNN1A	2750
SCNN1B	3161
GRM1	3201
TRPM4	3956
TAS2R46	4008
TAS1R2	5632
TAS1R1	7063
TRPM5	8132
TAS2R5	8657
GRM4	9166
TAS2R20	9914
TAS2R30	11468

---

REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S

REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S

	1150
set	REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S
setSize	53
pANOVA	0.0051
s.dist	0.222
p.adjustANOVA	0.226

Top enriched genes

Top 20 genes

GeneID	Gene Rank
EIF2S2	12010
RPS15A	11939
EIF3F	11563
RPS13	11420
RPS2	11169
RPS12	10945
RPS11	10361
RPS21	10276
RPS14	9890
RPS8	9803
RPS6	9691
EIF3G	9405
RPS5	9380
RPS16	9206
RPS7	8958
RPS10	8500
EIF4A2	7575
RPS18	7574
RPS28	7553
EIF4B	7164

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
EIF2S2	12010
RPS15A	11939
EIF3F	11563
RPS13	11420
RPS2	11169
RPS12	10945
RPS11	10361
RPS21	10276
RPS14	9890
RPS8	9803
RPS6	9691
EIF3G	9405
RPS5	9380
RPS16	9206
RPS7	8958
RPS10	8500
EIF4A2	7575
RPS18	7574
RPS28	7553
EIF4B	7164
RPS26	6403
RPS29	6202
FAU	6182
RPSA	5509
RPS23	4694
EIF2S1	4512
RPS20	4325
PABPC1	4184
EIF3B	3972
RPS24	3750
RPS27A	3415
RPS15	3030
RPS9	2957
EIF4E	2774
RPS27	2734
EIF3H	1949
RPS3	1293
EIF3I	438
RPS3A	-578
EIF3J	-1856
RPS27L	-2461
EIF3A	-2535
EIF3M	-2840
EIF4A1	-2862
EIF4H	-3503
RPS19	-3548
EIF3E	-3919
EIF3D	-4233
RPS25	-4512
EIF3K	-5313
EIF4G1	-6670
EIF3L	-7058
EIF4EBP1	-7305

---

REACTOME_SIGNALING_BY_TYPE_1_INSULIN_LIKE_GROWTH_FACTOR_1_RECEPTOR_IGF1R

REACTOME_SIGNALING_BY_TYPE_1_INSULIN_LIKE_GROWTH_FACTOR_1_RECEPTOR_IGF1R

	482
set	REACTOME_SIGNALING_BY_TYPE_1_INSULIN_LIKE_GROWTH_FACTOR_1_RECEPTOR_IGF1R
setSize	52
pANOVA	0.00524
s.dist	-0.224
p.adjustANOVA	0.226

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FGF17	-8899
FGF2	-8712
FGF8	-8519
FGF23	-8241
PDE3B	-7839
KLB	-7682
IGF1	-7671
IRS2	-7641
FGF7	-7611
THEM4	-7584
FLT3	-7171
FRS2	-7024
PIK3R1	-6466
FGF5	-6062
GRB2	-5790
PIK3C3	-5673
NRAS	-5634
PDPK1	-4919
FGF19	-4358
FGF18	-3774

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FGF17	-8899
FGF2	-8712
FGF8	-8519
FGF23	-8241
PDE3B	-7839
KLB	-7682
IGF1	-7671
IRS2	-7641
FGF7	-7611
THEM4	-7584
FLT3	-7171
FRS2	-7024
PIK3R1	-6466
FGF5	-6062
GRB2	-5790
PIK3C3	-5673
NRAS	-5634
PDPK1	-4919
FGF19	-4358
FGF18	-3774
TLR9	-3701
GAB1	-2761
FGF20	-2754
IGF1R	-2521
FGF4	-2221
FGF9	-2184
SOS1	-1653
FGF10	-1587
PIK3R2	-1452
SHC1	-599
HRAS	-327
PIK3CB	-320
FGFR4	57
PIK3CA	265
IGF2	1808
CILP	2443
GAB2	2954
FGF3	3249
FGF22	3783
FGF6	4751
FGF1	5299
FGFR1	5333
AKT2	5582
KL	6298
IRS1	6498
PIK3R4	6524
TRIB3	7010
KRAS	7289
FGFR2	7583
FLT3LG	8071
PTPN11	8945
FGFR3	10610

---

REACTOME_MITOCHONDRIAL_TRANSLATION

REACTOME_MITOCHONDRIAL_TRANSLATION

	874
set	REACTOME_MITOCHONDRIAL_TRANSLATION
setSize	93
pANOVA	0.00546
s.dist	0.167
p.adjustANOVA	0.23

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MRPL45	12063
MRPL21	11702
CHCHD1	10864
MRPL47	10831
MRPL24	10583
TUFM	10496
MTRF1L	10436
MRPL58	10358
MRPS12	10277
MRPL40	10249
MRPL19	10230
MRPL39	9909
MTIF3	9559
MRPS28	9520
MRPL18	9323
MRPS18A	9176
MRPS18C	9010
MRPL36	8745
MRPL13	8716
MRPL50	7788

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MRPL45	12063
MRPL21	11702
CHCHD1	10864
MRPL47	10831
MRPL24	10583
TUFM	10496
MTRF1L	10436
MRPL58	10358
MRPS12	10277
MRPL40	10249
MRPL19	10230
MRPL39	9909
MTIF3	9559
MRPS28	9520
MRPL18	9323
MRPS18A	9176
MRPS18C	9010
MRPL36	8745
MRPL13	8716
MRPL50	7788
MRPS25	7683
MRPL9	7586
MRPL52	7522
MRRF	7442
GFM2	6918
MRPL41	6904
MRPL49	6819
PTCD3	6666
MRPL46	6267
MRPS15	6184
MRPS14	6169
MRPS27	6079
MRPS9	5982
MRPL51	5828
MRPS30	5685
MRPL12	5485
MRPL30	5449
MRPS2	5398
MRPS11	5376
MRPL57	5332
MRPS16	5166
MRPL55	5129
MRPL42	4985
TSFM	4577
MRPS18B	4133
MRPL15	4096
MRPL22	4073
MRPL43	3705
MRPS34	3402
MRPS5	3134
MRPS10	3112
MRPS33	3100
MRPL27	2770
MRPS24	2421
MRPL16	2360
MRPL2	2274
MRPL28	2252
MRPL1	1977
MRPL14	1828
MRPL37	1653
MRPL48	1615
MRPL32	639
MRPL4	615
OXA1L	560
MTFMT	518
MRPS22	487
MRPL53	240
MRPS17	229
MRPS26	-204
MRPL54	-278
MRPL17	-408
MRPS21	-574
MRPS7	-583
MRPL10	-620
DAP3	-900
MRPS6	-2360
AURKAIP1	-2537
MRPL23	-2917
ERAL1	-3678
MRPL38	-3832
MRPS31	-3892
MRPL3	-4088
MRPS35	-4220
MRPL33	-5600
MRPS23	-6078
MTIF2	-6279
MRPL11	-6289
MRPL20	-6320
MRPL34	-6757
MRPL35	-6885
MRPL44	-7214
GADD45GIP1	-7407
GFM1	-7759

---

REACTOME_PI_3K_CASCADE_FGFR3

REACTOME_PI_3K_CASCADE_FGFR3

	947
set	REACTOME_PI_3K_CASCADE_FGFR3
setSize	17
pANOVA	0.00591
s.dist	-0.386
p.adjustANOVA	0.243

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FGF17	-8899
FGF2	-8712
FGF8	-8519
FGF23	-8241
FRS2	-7024
PIK3R1	-6466
FGF5	-6062
GRB2	-5790
FGF18	-3774
GAB1	-2761
FGF20	-2754
FGF4	-2221
FGF9	-2184
PIK3CA	265
FGF1	5299
PTPN11	8945
FGFR3	10610

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FGF17	-8899
FGF2	-8712
FGF8	-8519
FGF23	-8241
FRS2	-7024
PIK3R1	-6466
FGF5	-6062
GRB2	-5790
FGF18	-3774
GAB1	-2761
FGF20	-2754
FGF4	-2221
FGF9	-2184
PIK3CA	265
FGF1	5299
PTPN11	8945
FGFR3	10610

---

REACTOME_SARS_COV_2_HOST_INTERACTIONS

REACTOME_SARS_COV_2_HOST_INTERACTIONS

	1571
set	REACTOME_SARS_COV_2_HOST_INTERACTIONS
setSize	191
pANOVA	0.00666
s.dist	0.114
p.adjustANOVA	0.267

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IFNB1	12214
RPS15A	11939
NOD2	11840
HLA-B	11688
MASP1	11478
NUP88	11439
RPS13	11420
RPS2	11169
UBA52	11156
IFNA21	11080
RPS12	10945
POM121C	10915
SNRPF	10863
TUFM	10496
TRAF6	10486
TKFC	10399
RPS11	10361
RPS21	10276
UBC	9929
RPS14	9890

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IFNB1	12214.0
RPS15A	11939.0
NOD2	11840.0
HLA-B	11688.0
MASP1	11478.0
NUP88	11439.0
RPS13	11420.0
RPS2	11169.0
UBA52	11156.0
IFNA21	11080.0
RPS12	10945.0
POM121C	10915.0
SNRPF	10863.0
TUFM	10496.0
TRAF6	10486.0
TKFC	10399.0
RPS11	10361.0
RPS21	10276.0
UBC	9929.0
RPS14	9890.0
RPS8	9803.0
NUP42	9786.0
RPS6	9691.0
IRAK2	9569.0
RPS5	9380.0
RPS16	9206.0
TRIM4	9118.0
SNRPD2	9094.0
SIKE1	9051.0
RPS7	8958.0
PTPN11	8945.0
KPNA2	8879.0
HSP90AA1	8781.0
MBL2	8748.0
MASP2	8651.0
NUP43	8536.0
RPS10	8500.0
NUP62	8463.0
RIPK2	8428.0
HSP90AB1	8403.0
NUP107	8380.0
IFIH1	8321.0
HLA-C	8317.0
IKBKE	8307.0
NUP133	8148.0
TOMM70	8121.0
YWHAE	7894.0
B2M	7779.0
SNRPB	7733.0
RPS18	7574.0
RPS28	7553.0
SNRPG	7349.0
NUP155	7250.0
SFTPD	7197.0
SNRPD1	7039.0
GEMIN5	6943.0
TPR	6866.0
DDX20	6557.0
PIK3R4	6524.0
SNRPD3	6442.0
RPS26	6403.0
SEC24B	6280.0
CNBP	6240.0
RPS29	6202.0
FAU	6182.0
IRF3	5790.0
HLA-A	5686.0
AKT2	5582.0
RPSA	5509.0
NUP37	5379.0
SEC24A	5255.0
NUP93	5225.0
NUP188	5176.0
CAV1	5106.0
NUP160	4948.0
IFNA16	4779.0
RPS23	4694.0
GEMIN6	4536.0
NUP35	4415.0
AKT1	4367.0
RPS20	4325.0
IFNA13	4135.0
YWHAB	4065.0
NUP205	3947.0
IL17A	3888.0
SEC13	3809.0
RPS24	3750.0
UBE2V1	3719.0
RANBP2	3650.0
ATG14	3639.0
TBK1	3593.0
IFNA6	3495.0
IL17RC	3471.0
RPS27A	3415.0
VPS16	3390.0
ISG15	3326.0
IL17F	3301.0
IL17RA	3286.0
NUP54	3207.0
VPS41	3094.0
RPS15	3030.0
RPS9	2957.0
LARP1	2878.0
RPS27	2734.0
NUP98	2548.0
YWHAH	2374.0
IKBKB	2200.0
PATJ	2115.0
STAT1	2001.0
SEH1L	1872.0
RIGI	1713.0
GJA1	1465.0
TYK2	1442.0
RPS3	1293.0
VPS45	1275.0
IFNAR1	1035.0
UBE2N	980.0
NDC1	964.0
HLA-F	908.0
VPS11	861.0
IRF7	736.0
STAT2	725.0
HLA-E	647.0
RNF135	580.0
SMN1	64.5
SMN2	64.5
TJP1	-13.0
TRIM25	-73.0
JAK1	-159.0
YWHAQ	-274.0
SEC24D	-442.0
RPS3A	-578.0
CHUK	-758.0
VPS18	-1041.0
BECN1	-1114.0
IFNA2	-1244.0
MAVS	-1327.0
SAR1B	-1427.0
UBB	-1544.0
VPS33A	-1918.0
VPS39	-2229.0
TLR2	-2299.0
GEMIN7	-2406.0
RPS27L	-2461.0
AAAS	-2517.0
NLRP12	-2548.0
UVRAG	-2872.0
MAP1LC3B	-3004.0
G3BP2	-3181.0
PTPN6	-3251.0
SEC23A	-3439.0
YWHAZ	-3448.0
YWHAG	-3454.0
IFNA1	-3508.0
IFNA7	-3509.0
RPS19	-3548.0
TAB2	-3591.0
TRAF3	-3655.0
AKT3	-3729.0
SEC24C	-3912.0
NUP153	-3940.0
NUP210	-3969.0
NUP50	-3978.0
STING1	-4068.0
RPS25	-4512.0
PDPK1	-4919.0
TAB1	-4920.0
MAP3K7	-4923.0
IFNAR2	-5172.0
NUP214	-5218.0
GEMIN2	-5476.0
HLA-G	-5558.0
PIK3C3	-5673.0
NUP58	-5770.0
IFNA14	-5915.0
G3BP1	-6034.0
GEMIN4	-6343.0
PALS1	-6618.0
NOD1	-6794.0
NLRP3	-6924.0
RAE1	-6991.0
CREBBP	-7240.0
VPS33B	-7276.0
NUP85	-7391.0
CRB3	-7440.0
IFNA5	-7447.0
SNRPE	-7549.0
IFNA8	-8008.0
TLR1	-8073.0
POM121	-8428.0
SFN	-8545.0

---

REACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS

REACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS

	973
set	REACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS
setSize	418
pANOVA	0.00746
s.dist	-0.0763
p.adjustANOVA	0.276

Top enriched genes

Top 20 genes

GeneID	Gene Rank
AREG	-9574
EPGN	-9325
BIN2	-9234
SPRED3	-9223
FGF17	-8899
LCK	-8743
FGF2	-8712
MRAS	-8672
STAT3	-8571
FGF8	-8519
RAP1B	-8270
KIT	-8261
FGF23	-8241
DCTN1	-8145
CNTRL	-8135
POLR2J	-8074
AXIN1	-7973
ETV6	-7953
PPP2CB	-7833
MYH9	-7715

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
AREG	-9574
EPGN	-9325
BIN2	-9234
SPRED3	-9223
FGF17	-8899
LCK	-8743
FGF2	-8712
MRAS	-8672
STAT3	-8571
FGF8	-8519
RAP1B	-8270
KIT	-8261
FGF23	-8241
DCTN1	-8145
CNTRL	-8135
POLR2J	-8074
AXIN1	-7973
ETV6	-7953
PPP2CB	-7833
MYH9	-7715
ACTG1	-7690
KLB	-7682
BCL11A	-7646
IRS2	-7641
PSMA8	-7628
PPM1B	-7622
FGF7	-7611
ARRB2	-7590
PPP2R5B	-7552
CD28	-7523
PSME4	-7369
KDR	-7338
CNKSR1	-7281
CREBBP	-7240
FLT3	-7171
STAT5B	-7052
FRS2	-7024
TGFBR2	-6999
RAC2	-6931
CSK	-6864
MLST8	-6792
PHB1	-6778
BRAF	-6754
FZD8	-6620
NRG4	-6586
HDAC2	-6527
PSME1	-6518
PIK3R1	-6466
FXR1	-6355
PSMB7	-6344
MPRIP	-6266
RBX1	-6240
BCR	-6189
FGF5	-6062
WDR48	-6056
CALM1	-6055
NPM1	-5982
HEY1	-5920
DKK4	-5834
BIRC6	-5831
GRB2	-5790
GOLGA4	-5765
RAC1	-5691
BRAP	-5681
PSMD12	-5677
MYO18A	-5665
TRIM24	-5643
NRAS	-5634
PSENEN	-5624
POLR2E	-5528
NOTCH1	-5522
NCOR2	-5461
RPS6KB2	-5414
CASP9	-5196
NEURL1	-5130
CUX1	-5038
PPP2R5C	-5022
PDPK1	-4919
TFG	-4854
MAP2K1	-4845
GTF2F2	-4815
HDAC9	-4756
PSMB10	-4752
PSMD11	-4724
FGFR1OP2	-4706
APBB1IP	-4652
KIF5B	-4641
STAT5A	-4603
ERBB3	-4568
LRRFIP1	-4565
DLL1	-4474
FOXO1	-4399
CUL1	-4380
FGF19	-4358
ERBB2	-4345
APH1B	-4269
FAM131B	-4158
WNT3A	-4124
KREMEN2	-4101
POLR2C	-4056
NCBP1	-4046
PIK3CD	-4024
CARS1	-3870
NRG1	-3853
PSMD7	-3845
PSMF1	-3809
FZD5	-3808
FGF18	-3774
AKT3	-3729
KITLG	-3634
PSMA5	-3601
KLC1	-3600
RAP1A	-3445
BTC	-3440
LMO7	-3382
TRAT1	-3373
JUNB	-3356
MARK3	-3343
CDC37	-3222
LMNA	-3215
PTPN12	-3116
CDKN1A	-3095
MIB1	-3067
HEY2	-3020
GCC2	-2978
CBL	-2887
VCL	-2878
HDAC4	-2873
ITGA2B	-2859
PSMD9	-2789
KSR1	-2770
GAB1	-2761
FGF20	-2754
MAPK1	-2642
AKAP9	-2604
PSMA1	-2596
SMAD3	-2578
PPP2CA	-2522
HEYL	-2467
CTBP1	-2459
ADAM17	-2450
PSEN1	-2394
TRAK1	-2312
EML4	-2252
FGF4	-2221
IQGAP1	-2189
FGF9	-2184
AGTRAP	-2158
MAML1	-2115
LRP6	-2044
POLR2K	-2038
TNKS	-2022
SMAD4	-2012
CEP43	-1989
DUSP8	-1982
PAPSS1	-1912
TENT4A	-1869
ACTB	-1798
RRBP1	-1716
DUSP16	-1687
JAG1	-1671
SOS1	-1653
BAG4	-1640
OS9	-1591
FGF10	-1587
SHOC2	-1576
KAT2B	-1573
UBB	-1544
NCOR1	-1537
ERLIN2	-1516
FKBP1A	-1493
PIK3R2	-1452
DHH	-1436
NEURL1B	-1398
PPP2R5E	-1359
TPM3	-1240
PSEN2	-1236
ZMYM2	-1173
DUSP7	-1142
FZD6	-1064
DUSP10	-999
SEL1L	-924
PSMD1	-859
FOXO3	-858
PSMD4	-820
PPP1CB	-817
CLTC	-809
CHUK	-758
SHC1	-599
MAPKAP1	-596
KANK1	-594
KSR2	-539
VWF	-494
EEF1G	-486
PSMD6	-426
MAP3K11	-341
HHAT	-337
HDAC7	-329
HRAS	-327
PIK3CB	-320
PPFIBP1	-193
RAF1	-132
PSMD5	-130
FGFR4	57
PSMB4	130
POLR2L	160
QKI	238
POLR2I	261
PIK3CA	265
SQSTM1	269
RHOG	285
GSK3B	349
PSMD2	365
SRC	374
SND1	426
FBXW7	462
PSMD3	478
CAMK2D	480
SHH	611
SPTBN1	613
CEBPB	710
PRKAR1A	781
ITGB3	876
LYN	942
FGB	954
MIB2	961
CDKN1B	1029
NRG2	1083
PSMA2	1209
AGK	1259
SKP1	1262
IHH	1263
TBL1XR1	1306
NR4A1	1313
ZC3HAV1	1362
FYN	1368
CAMK2G	1402
PSMB1	1426
MAML3	1431
PSMC2	1501
CPSF6	1521
CLCN6	1538
NF1	1620
ADAM10	1686
PSMA4	1771
SMAD2	1832
TSC2	1859
GSK3A	1862
ESR1	1866
CTNNB1	1963
ZC3HC1	1969
PIK3AP1	1980
STAT1	2001
PSMA6	2004
DKK2	2089
ESRP1	2129
DKK1	2132
PSMC4	2167
YES1	2253
ERLEC1	2320
STRN	2370
PSME3	2564
HDAC10	2655
PSMA3	2680
CD86	2708
PDGFB	2819
POLR2H	2882
GAB2	2954
HDAC1	3008
NOX4	3019
CREB1	3039
PSMA7	3056
PDGFRB	3116
EIF2AK3	3130
MAPK3	3132
HIP1	3220
FGF3	3249
MAP2K2	3256
ATG7	3284
RPS27A	3415
PSMB8	3437
TCF7L2	3502
BAD	3507
RICTOR	3550
SEM1	3569
ARRB1	3626
AKT1S1	3638
RANBP2	3650
LRP5	3665
PPP2R5A	3729
FGF22	3783
POLR2G	3785
POLR2A	3845
PDGFA	3935
ZFYVE9	3955
MDM2	3971
APC	4026
YWHAB	4065
MAML2	4070
APH1A	4220
PPP1CC	4343
AKT1	4367
HES5	4386
ESR2	4487
HDAC11	4504
SEC31A	4621
POLR2D	4651
FGF6	4751
TGFB1	4753
RBPJ	4768
CTBP2	4788
PSMC5	4808
PSMB6	4820
PSMD14	4844
AP3B1	5082
TLN1	5153
SYVN1	5214
FGF1	5299
TRIP11	5301
VAV1	5316
FGFR1	5333
PIK3R3	5467
ERBB4	5505
TGFBR1	5543
AKT2	5582
SNW1	5583
PRR5	5914
KDM7A	5939
DUSP6	5979
NRG3	6008
ERBIN	6029
DLL4	6069
MTOR	6074
NCBP2	6104
PSMD13	6257
KL	6298
PTEN	6389
TGFA	6391
EGF	6426
MYC	6453
IRS1	6498
HDAC5	6505
KIAA1549	6623
RNF213	6642
PDGFRA	6692
KREMEN1	6703
FIP1L1	6797
HDAC3	6800
POLR2F	6801
TPR	6866
MET	6900
SPRED2	6908
NCSTN	6909
PIM1	6951
CSNK1A1	7131
BCL2L1	7176
PSMB3	7215
EP300	7241
TNKS2	7276
KRAS	7289
KAT2A	7376
PPP2R1B	7392
ALK	7498
PSMB5	7505
WDCP	7577
FGFR2	7583
GTF2F1	7678
HES1	7701
PSMC6	7767
RNF43	7789
JAK2	7835
POLR2B	7880
FAM114A2	7961
FN1	8022
PSMD8	8061
FLT3LG	8071
CD19	8092
HGF	8166
SPRED1	8177
PSME2	8279
PSMB9	8387
PSMB2	8481
HBEGF	8713
DERL2	8766
HSP90AA1	8781
CDK8	8834
CD80	8939
PTPN11	8945
FRS3	8968
PPP2R1A	9045
VCP	9162
BCL2A1	9238
ATIC	9281
PSMC1	9539
RPS6	9691
JAG2	9766
PSMC3	9795
TPM4	9898
UBC	9929
PLCG1	9968
BCL2L11	9992
EGFR	10025
AGGF1	10073
CAMK2B	10096
FGA	10283
CCNC	10354
EREG	10360
FGFR3	10610
PPP2R5D	11025
CAMK2A	11048
FZD4	11095
PEBP1	11133
UBA52	11156
FGG	11386
PSMB11	11475
GOLGB1	11807
ICOS	11859
FOXO6	12115

---

REACTOME_RESPIRATORY_ELECTRON_TRANSPORT

REACTOME_RESPIRATORY_ELECTRON_TRANSPORT

	1026
set	REACTOME_RESPIRATORY_ELECTRON_TRANSPORT
setSize	90
pANOVA	0.00757
s.dist	0.163
p.adjustANOVA	0.276

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NDUFB4	11611
COX8A	11577
NDUFA8	11172
NDUFB5	11001
COX7A2L	10919
NDUFAF7	10605
ETFDH	10556
SURF1	10342
COX11	10259
TIMMDC1	9931
TMEM186	9826
NDUFA2	9811
NDUFA7	9777
CYCS	9672
NDUFS1	9637
NDUFB1	9620
COX6C	9611
NDUFB8	9461
NDUFA4	9431
SDHD	9040

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
NDUFB4	11611
COX8A	11577
NDUFA8	11172
NDUFB5	11001
COX7A2L	10919
NDUFAF7	10605
ETFDH	10556
SURF1	10342
COX11	10259
TIMMDC1	9931
TMEM186	9826
NDUFA2	9811
NDUFA7	9777
CYCS	9672
NDUFS1	9637
NDUFB1	9620
COX6C	9611
NDUFB8	9461
NDUFA4	9431
SDHD	9040
NDUFA12	8994
COX6A1	8970
UQCRFS1	8789
SDHB	8561
UQCR11	8501
NDUFS6	8440
NDUFAF4	8213
NDUFA9	8189
COX20	7260
COQ10B	7184
NDUFA6	7102
COX16	6220
NUBPL	6187
NDUFAF3	5846
COX5B	5773
NDUFAF5	5713
NDUFA11	5705
UQCRB	5554
NDUFS7	5437
NDUFB6	5222
NDUFA5	3724
NDUFV2	3647
NDUFB9	3615
TMEM126B	3606
SDHC	3355
NDUFS5	3104
NDUFB7	2999
UQCRQ	2971
NDUFAF6	2561
UQCR10	2244
ETFA	2053
SCO1	2049
ECSIT	1902
COQ10A	1847
NDUFAF1	1684
NDUFV3	1643
NDUFAF2	1629
COX4I1	1499
NDUFB3	1440
NDUFV1	828
COA1	509
COX14	445
NDUFS2	404
NDUFA10	233
NDUFS4	-71
UQCRH	-643
NDUFA3	-826
NDUFB2	-902
COX18	-1734
NDUFS3	-2009
TACO1	-2553
COX19	-3009
COX7C	-3401
NDUFC1	-3564
COX5A	-3835
SDHA	-3838
LRPPRC	-3918
CYC1	-3998
NDUFB10	-4676
TRAP1	-4778
ACAD9	-4814
NDUFAB1	-5195
NDUFS8	-5304
NDUFC2	-5459
UQCRC2	-6390
UQCRC1	-7092
COX6B1	-7172
SCO2	-7514
ETFB	-7901
NDUFA13	-8575

---

REACTOME_PI_3K_CASCADE_FGFR2

REACTOME_PI_3K_CASCADE_FGFR2

	941
set	REACTOME_PI_3K_CASCADE_FGFR2
setSize	22
pANOVA	0.00759
s.dist	-0.329
p.adjustANOVA	0.276

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FGF17	-8899
FGF2	-8712
FGF8	-8519
FGF23	-8241
FGF7	-7611
FRS2	-7024
PIK3R1	-6466
FGF5	-6062
GRB2	-5790
FGF18	-3774
GAB1	-2761
FGF20	-2754
FGF4	-2221
FGF9	-2184
FGF10	-1587
PIK3CA	265
FGF3	3249
FGF22	3783
FGF6	4751
FGF1	5299

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FGF17	-8899
FGF2	-8712
FGF8	-8519
FGF23	-8241
FGF7	-7611
FRS2	-7024
PIK3R1	-6466
FGF5	-6062
GRB2	-5790
FGF18	-3774
GAB1	-2761
FGF20	-2754
FGF4	-2221
FGF9	-2184
FGF10	-1587
PIK3CA	265
FGF3	3249
FGF22	3783
FGF6	4751
FGF1	5299
FGFR2	7583
PTPN11	8945

---

REACTOME_SIGNALING_BY_MEMBRANE_TETHERED_FUSIONS_OF_PDGFRA_OR_PDGFRB

REACTOME_SIGNALING_BY_MEMBRANE_TETHERED_FUSIONS_OF_PDGFRA_OR_PDGFRB

	1534
set	REACTOME_SIGNALING_BY_MEMBRANE_TETHERED_FUSIONS_OF_PDGFRA_OR_PDGFRB
setSize	5
pANOVA	0.00766
s.dist	-0.689
p.adjustANOVA	0.276

Top enriched genes

Top 20 genes

GeneID	Gene Rank
BIN2	-9234
ETV6	-7953
KDR	-7338
GOLGA4	-5765
KANK1	-594

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
BIN2	-9234
ETV6	-7953
KDR	-7338
GOLGA4	-5765
KANK1	-594

---

REACTOME_ANCHORING_FIBRIL_FORMATION

REACTOME_ANCHORING_FIBRIL_FORMATION

	476
set	REACTOME_ANCHORING_FIBRIL_FORMATION
setSize	13
pANOVA	0.00773
s.dist	0.427
p.adjustANOVA	0.276

Top enriched genes

Top 20 genes

GeneID	Gene Rank
COL7A1	11113
BMP1	11039
LAMB3	11033
LAMC2	8412
COL4A2	7381
COL4A4	7310
TLL1	5794
TLL2	5311
COL1A2	4840
COL4A1	3695
COL4A3	3687
COL1A1	2731
LAMA3	-3170

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
COL7A1	11113
BMP1	11039
LAMB3	11033
LAMC2	8412
COL4A2	7381
COL4A4	7310
TLL1	5794
TLL2	5311
COL1A2	4840
COL4A1	3695
COL4A3	3687
COL1A1	2731
LAMA3	-3170

---

REACTOME_IRS_MEDIATED_SIGNALLING

REACTOME_IRS_MEDIATED_SIGNALLING

	36
set	REACTOME_IRS_MEDIATED_SIGNALLING
setSize	47
pANOVA	0.00866
s.dist	-0.221
p.adjustANOVA	0.303

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FGF17	-8899
FGF2	-8712
FGF8	-8519
FGF23	-8241
PDE3B	-7839
KLB	-7682
IRS2	-7641
FGF7	-7611
THEM4	-7584
FLT3	-7171
FRS2	-7024
PIK3R1	-6466
FGF5	-6062
GRB2	-5790
PIK3C3	-5673
NRAS	-5634
PDPK1	-4919
FGF19	-4358
FGF18	-3774
TLR9	-3701

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FGF17	-8899
FGF2	-8712
FGF8	-8519
FGF23	-8241
PDE3B	-7839
KLB	-7682
IRS2	-7641
FGF7	-7611
THEM4	-7584
FLT3	-7171
FRS2	-7024
PIK3R1	-6466
FGF5	-6062
GRB2	-5790
PIK3C3	-5673
NRAS	-5634
PDPK1	-4919
FGF19	-4358
FGF18	-3774
TLR9	-3701
GAB1	-2761
FGF20	-2754
FGF4	-2221
FGF9	-2184
SOS1	-1653
FGF10	-1587
PIK3R2	-1452
HRAS	-327
PIK3CB	-320
FGFR4	57
PIK3CA	265
GAB2	2954
FGF3	3249
FGF22	3783
FGF6	4751
FGF1	5299
FGFR1	5333
AKT2	5582
KL	6298
IRS1	6498
PIK3R4	6524
TRIB3	7010
KRAS	7289
FGFR2	7583
FLT3LG	8071
PTPN11	8945
FGFR3	10610

---

REACTOME_PLATELET_CALCIUM_HOMEOSTASIS

REACTOME_PLATELET_CALCIUM_HOMEOSTASIS

	703
set	REACTOME_PLATELET_CALCIUM_HOMEOSTASIS
setSize	27
pANOVA	0.00922
s.dist	-0.289
p.adjustANOVA	0.316

Top enriched genes

Top 20 genes

GeneID	Gene Rank
P2RX7	-6264
P2RX5	-6202
CALM1	-6055
SLC8A1	-5727
ATP2A2	-5563
P2RX1	-5410
ITPR1	-4828
SLC8A3	-4355
P2RX6	-4286
ATP2A1	-4204
STIM1	-3815
P2RX2	-3629
ATP2B4	-3474
TRPC6	-3460
TRPC3	-2694
SRI	-1777
SLC8A2	-1356
ORAI2	-559
ITPR2	115
ATP2B1	658

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
P2RX7	-6264
P2RX5	-6202
CALM1	-6055
SLC8A1	-5727
ATP2A2	-5563
P2RX1	-5410
ITPR1	-4828
SLC8A3	-4355
P2RX6	-4286
ATP2A1	-4204
STIM1	-3815
P2RX2	-3629
ATP2B4	-3474
TRPC6	-3460
TRPC3	-2694
SRI	-1777
SLC8A2	-1356
ORAI2	-559
ITPR2	115
ATP2B1	658
TRPC7	1503
ITPR3	1682
P2RX3	1897
P2RX4	2505
ATP2A3	2684
ORAI1	5739
ATP2B2	8754

---

REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS

REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS

	819
set	REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS
setSize	32
pANOVA	0.0103
s.dist	-0.262
p.adjustANOVA	0.343

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GNG8	-9227
F2RL2	-8822
GNG11	-8031
ARRB2	-7590
GNG2	-7528
GNB4	-7149
F2RL3	-5978
GNB1	-4992
GNB3	-4659
GNG3	-4493
F2	-3871
GNA14	-3794
GNAQ	-3714
GNB5	-3516
GNG7	-3459
GNG4	-3344
GNA12	-3205
GNA13	-3172
GNA15	-2817
MAPK1	-2642

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GNG8	-9227
F2RL2	-8822
GNG11	-8031
ARRB2	-7590
GNG2	-7528
GNB4	-7149
F2RL3	-5978
GNB1	-4992
GNB3	-4659
GNG3	-4493
F2	-3871
GNA14	-3794
GNAQ	-3714
GNB5	-3516
GNG7	-3459
GNG4	-3344
GNA12	-3205
GNA13	-3172
GNA15	-2817
MAPK1	-2642
GNB2	-1313
SRC	374
GNA11	1321
GNG13	2555
MAPK3	3132
GNGT1	3417
ARRB1	3626
GNG5	6696
GNGT2	7037
F2R	7737
GNG12	9662
GNG10	10359

---

REACTOME_DEFECTIVE_F9_ACTIVATION

REACTOME_DEFECTIVE_F9_ACTIVATION

	1532
set	REACTOME_DEFECTIVE_F9_ACTIVATION
setSize	5
pANOVA	0.0105
s.dist	-0.661
p.adjustANOVA	0.343

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GP1BA	-9058
GP1BB	-8361
GP5	-7154
GP9	-7090
F11	2290

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GP1BA	-9058
GP1BB	-8361
GP5	-7154
GP9	-7090
F11	2290

---

Here is the session info with all the versions of packages used.

sessionInfo()

## R version 4.3.2 (2023-10-31)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.3 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3 
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so;  LAPACK version 3.10.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Etc/UTC
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.3.3                                      
##  [2] GGally_2.2.0                                       
##  [3] ggplot2_3.4.4                                      
##  [4] reshape2_1.4.4                                     
##  [5] gtools_3.9.5                                       
##  [6] tibble_3.2.1                                       
##  [7] dplyr_1.1.4                                        
##  [8] echarts4r_0.4.5                                    
##  [9] png_0.1-8                                          
## [10] gridExtra_2.3                                      
## [11] missMethyl_1.36.0                                  
## [12] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.1 
## [13] beeswarm_0.4.0                                     
## [14] kableExtra_1.3.4                                   
## [15] gplots_3.1.3                                       
## [16] mitch_1.15.0                                       
## [17] tictoc_1.2                                         
## [18] HGNChelper_0.8.1                                   
## [19] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [20] IlluminaHumanMethylation450kmanifest_0.4.0         
## [21] minfi_1.48.0                                       
## [22] bumphunter_1.44.0                                  
## [23] locfit_1.5-9.8                                     
## [24] iterators_1.0.14                                   
## [25] foreach_1.5.2                                      
## [26] Biostrings_2.70.1                                  
## [27] XVector_0.42.0                                     
## [28] SummarizedExperiment_1.32.0                        
## [29] Biobase_2.62.0                                     
## [30] MatrixGenerics_1.14.0                              
## [31] matrixStats_1.2.0                                  
## [32] GenomicRanges_1.54.1                               
## [33] GenomeInfoDb_1.38.2                                
## [34] IRanges_2.36.0                                     
## [35] S4Vectors_0.40.2                                   
## [36] BiocGenerics_0.48.1                                
## [37] eulerr_7.0.0                                       
## [38] limma_3.58.1                                       
## 
## loaded via a namespace (and not attached):
##   [1] splines_4.3.2             later_1.3.2              
##   [3] BiocIO_1.12.0             bitops_1.0-7             
##   [5] filelock_1.0.3            preprocessCore_1.64.0    
##   [7] XML_3.99-0.16             lifecycle_1.0.4          
##   [9] lattice_0.22-5            MASS_7.3-60              
##  [11] base64_2.0.1              scrime_1.3.5             
##  [13] magrittr_2.0.3            sass_0.4.8               
##  [15] rmarkdown_2.25            jquerylib_0.1.4          
##  [17] yaml_2.3.8                httpuv_1.6.13            
##  [19] doRNG_1.8.6               askpass_1.2.0            
##  [21] DBI_1.1.3                 RColorBrewer_1.1-3       
##  [23] abind_1.4-5               zlibbioc_1.48.0          
##  [25] rvest_1.0.3               quadprog_1.5-8           
##  [27] purrr_1.0.2               RCurl_1.98-1.13          
##  [29] rappdirs_0.3.3            GenomeInfoDbData_1.2.11  
##  [31] genefilter_1.84.0         annotate_1.80.0          
##  [33] svglite_2.1.3             DelayedMatrixStats_1.24.0
##  [35] codetools_0.2-19          DelayedArray_0.28.0      
##  [37] xml2_1.3.6                tidyselect_1.2.0         
##  [39] beanplot_1.3.1            BiocFileCache_2.10.1     
##  [41] webshot_0.5.5             illuminaio_0.44.0        
##  [43] GenomicAlignments_1.38.0  jsonlite_1.8.8           
##  [45] multtest_2.58.0           ellipsis_0.3.2           
##  [47] survival_3.5-7            systemfonts_1.0.5        
##  [49] tools_4.3.2               progress_1.2.3           
##  [51] Rcpp_1.0.11               glue_1.6.2               
##  [53] SparseArray_1.2.2         xfun_0.41                
##  [55] HDF5Array_1.30.0          withr_2.5.2              
##  [57] fastmap_1.1.1             rhdf5filters_1.14.1      
##  [59] fansi_1.0.6               openssl_2.1.1            
##  [61] caTools_1.18.2            digest_0.6.33            
##  [63] R6_2.5.1                  mime_0.12                
##  [65] colorspace_2.1-0          biomaRt_2.58.0           
##  [67] RSQLite_2.3.4             utf8_1.2.4               
##  [69] tidyr_1.3.0               generics_0.1.3           
##  [71] data.table_1.14.10        rtracklayer_1.62.0       
##  [73] prettyunits_1.2.0         httr_1.4.7               
##  [75] htmlwidgets_1.6.4         S4Arrays_1.2.0           
##  [77] ggstats_0.5.1             pkgconfig_2.0.3          
##  [79] gtable_0.3.4              blob_1.2.4               
##  [81] siggenes_1.76.0           htmltools_0.5.7          
##  [83] scales_1.3.0              rstudioapi_0.15.0        
##  [85] knitr_1.45                tzdb_0.4.0               
##  [87] rjson_0.2.21              nlme_3.1-163             
##  [89] curl_5.2.0                org.Hs.eg.db_3.18.0      
##  [91] cachem_1.0.8              rhdf5_2.46.1             
##  [93] stringr_1.5.1             KernSmooth_2.23-22       
##  [95] AnnotationDbi_1.64.1      restfulr_0.0.15          
##  [97] GEOquery_2.70.0           pillar_1.9.0             
##  [99] grid_4.3.2                reshape_0.8.9            
## [101] vctrs_0.6.5               promises_1.2.1           
## [103] dbplyr_2.4.0              xtable_1.8-4             
## [105] evaluate_0.23             readr_2.1.4              
## [107] GenomicFeatures_1.54.1    cli_3.6.2                
## [109] compiler_4.3.2            Rsamtools_2.18.0         
## [111] rlang_1.1.2               crayon_1.5.2             
## [113] rngtools_1.5.2            nor1mix_1.3-2            
## [115] mclust_6.0.1              plyr_1.8.9               
## [117] stringi_1.8.3             viridisLite_0.4.2        
## [119] BiocParallel_1.36.0       munsell_0.5.0            
## [121] Matrix_1.6-1.1            hms_1.1.3                
## [123] sparseMatrixStats_1.14.0  bit64_4.0.5              
## [125] Rhdf5lib_1.24.1           KEGGREST_1.42.0          
## [127] statmod_1.5.0             shiny_1.8.0              
## [129] highr_0.10                memoise_2.0.1            
## [131] bslib_0.6.1               bit_4.0.5

END of report