date generated: 2024-01-18

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch
x
A1BG 0.0024093
A1BG-AS1 0.0030394
A1CF -0.0003764
A2M 0.0010127
A2M-AS1 0.0117930
A2ML1 0.0004472

Here are some metrics about the input data profile:

Profiling data metrics
Profile metrics
num_genesets 1654
num_genes_in_profile 22007
duplicated_genes_present 0
num_profile_genes_in_sets 10383
num_profile_genes_not_in_sets 11624

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets: c2.cp.reactome.v2023.1.Hs.symbols.gmt
Gene set metrics
Gene sets metrics
num_genesets 1654
num_genesets_excluded 365
num_genesets_included 1289

Differential pathway expression


Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

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## in kable. kableExtra can customize either HTML or LaTeX outputs. See
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set setSize pANOVA s.dist p.adjustANOVA
REACTOME TRANSLATION 278 3.16e-11 -0.2310 5.19e-08
REACTOME EUKARYOTIC TRANSLATION INITIATION 110 7.17e-09 -0.3190 5.89e-06
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE 105 7.65e-08 -0.3040 4.18e-05
REACTOME METABOLISM OF RNA 675 1.10e-07 -0.1200 4.52e-05
REACTOME RRNA PROCESSING 192 3.45e-07 -0.2130 1.13e-04
REACTOME EUKARYOTIC TRANSLATION ELONGATION 87 1.24e-06 -0.3010 3.39e-04
REACTOME SELENOAMINO ACID METABOLISM 108 2.05e-06 -0.2640 4.81e-04
REACTOME NONSENSE MEDIATED DECAY NMD 107 3.13e-06 -0.2610 6.43e-04
REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES 353 5.08e-06 -0.1410 8.10e-04
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY 94 5.09e-06 -0.2720 8.10e-04
REACTOME INFLUENZA INFECTION 149 5.43e-06 -0.2160 8.10e-04
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS 161 1.08e-05 -0.2010 1.48e-03
REACTOME EXTRACELLULAR MATRIX ORGANIZATION 291 3.38e-05 0.1410 4.27e-03
REACTOME RHO GTPASE CYCLE 423 4.77e-05 0.1150 5.60e-03
REACTOME SIGNALING BY GPCR 673 5.43e-05 0.0912 5.95e-03
REACTOME SARS COV 1 HOST INTERACTIONS 92 6.08e-05 -0.2420 6.24e-03
REACTOME COSTIMULATION BY THE CD28 FAMILY 64 1.12e-04 0.2790 1.05e-02
REACTOME SARS COV 2 HOST INTERACTIONS 191 1.15e-04 -0.1620 1.05e-02
REACTOME CELL CYCLE MITOTIC 539 1.35e-04 -0.0961 1.16e-02
REACTOME CELL CYCLE 666 1.69e-04 -0.0855 1.38e-02
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S 53 1.80e-04 -0.2970 1.41e-02
REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY 46 3.27e-04 -0.3060 2.42e-02
REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS 27 3.39e-04 0.3980 2.42e-02
REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS 81 3.77e-04 0.2290 2.58e-02
REACTOME SIGNALING BY NODAL 20 6.67e-04 0.4390 4.38e-02
REACTOME CDC42 GTPASE CYCLE 144 7.14e-04 0.1630 4.51e-02
REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS 111 7.47e-04 -0.1850 4.55e-02
REACTOME SIGNALING BY ROBO RECEPTORS 206 7.89e-04 -0.1360 4.63e-02
REACTOME SYNTHESIS OF LIPOXINS LX 6 8.25e-04 0.7880 4.67e-02
REACTOME PHOSPHOLIPID METABOLISM 201 8.55e-04 0.1360 4.68e-02
REACTOME RESPIRATORY ELECTRON TRANSPORT 90 1.10e-03 -0.1990 5.61e-02
REACTOME ELASTIC FIBRE FORMATION 44 1.13e-03 0.2840 5.61e-02
REACTOME RAC1 GTPASE CYCLE 172 1.13e-03 0.1440 5.61e-02
REACTOME CD28 CO STIMULATION 32 1.24e-03 0.3300 5.97e-02
REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES 39 1.28e-03 -0.2980 6.00e-02
REACTOME RHOA GTPASE CYCLE 142 1.52e-03 0.1540 6.95e-02
REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS 20 1.74e-03 0.4040 7.72e-02
REACTOME RHOB GTPASE CYCLE 67 1.95e-03 0.2190 8.42e-02
REACTOME SARS COV 1 INFECTION 136 2.11e-03 -0.1530 8.88e-02
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION 250 2.25e-03 0.1120 9.07e-02
REACTOME CELL CYCLE CHECKPOINTS 284 2.27e-03 -0.1050 9.07e-02
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY 33 2.32e-03 -0.3060 9.07e-02
REACTOME MITOCHONDRIAL TRANSLATION 93 2.38e-03 -0.1820 9.09e-02
REACTOME MITOTIC G2 G2 M PHASES 194 2.47e-03 -0.1260 9.23e-02
REACTOME NRAGE SIGNALS DEATH THROUGH JNK 53 2.58e-03 0.2390 9.41e-02
REACTOME INTERFERON ALPHA BETA SIGNALING 70 2.65e-03 -0.2080 9.46e-02
REACTOME INTERFERON SIGNALING 193 2.76e-03 -0.1250 9.63e-02
REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL 58 2.82e-03 -0.2270 9.64e-02
REACTOME HEMOSTASIS 591 3.01e-03 0.0714 1.01e-01
REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES 80 3.08e-03 -0.1910 1.01e-01


Results (complete table)


Click HERE to show results for all gene sets

Complete results
set setSize pANOVA s.dist p.adjustANOVA
REACTOME TRANSLATION 278 3.16e-11 -2.31e-01 5.19e-08
REACTOME EUKARYOTIC TRANSLATION INITIATION 110 7.17e-09 -3.19e-01 5.89e-06
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE 105 7.65e-08 -3.04e-01 4.18e-05
REACTOME METABOLISM OF RNA 675 1.10e-07 -1.20e-01 4.52e-05
REACTOME RRNA PROCESSING 192 3.45e-07 -2.13e-01 1.13e-04
REACTOME EUKARYOTIC TRANSLATION ELONGATION 87 1.24e-06 -3.01e-01 3.39e-04
REACTOME SELENOAMINO ACID METABOLISM 108 2.05e-06 -2.64e-01 4.81e-04
REACTOME NONSENSE MEDIATED DECAY NMD 107 3.13e-06 -2.61e-01 6.43e-04
REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES 353 5.08e-06 -1.41e-01 8.10e-04
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY 94 5.09e-06 -2.72e-01 8.10e-04
REACTOME INFLUENZA INFECTION 149 5.43e-06 -2.16e-01 8.10e-04
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS 161 1.08e-05 -2.01e-01 1.48e-03
REACTOME EXTRACELLULAR MATRIX ORGANIZATION 291 3.38e-05 1.41e-01 4.27e-03
REACTOME RHO GTPASE CYCLE 423 4.77e-05 1.15e-01 5.60e-03
REACTOME SIGNALING BY GPCR 673 5.43e-05 9.12e-02 5.95e-03
REACTOME SARS COV 1 HOST INTERACTIONS 92 6.08e-05 -2.42e-01 6.24e-03
REACTOME COSTIMULATION BY THE CD28 FAMILY 64 1.12e-04 2.79e-01 1.05e-02
REACTOME SARS COV 2 HOST INTERACTIONS 191 1.15e-04 -1.62e-01 1.05e-02
REACTOME CELL CYCLE MITOTIC 539 1.35e-04 -9.61e-02 1.16e-02
REACTOME CELL CYCLE 666 1.69e-04 -8.55e-02 1.38e-02
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S 53 1.80e-04 -2.97e-01 1.41e-02
REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY 46 3.27e-04 -3.06e-01 2.42e-02
REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS 27 3.39e-04 3.98e-01 2.42e-02
REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS 81 3.77e-04 2.29e-01 2.58e-02
REACTOME SIGNALING BY NODAL 20 6.67e-04 4.39e-01 4.38e-02
REACTOME CDC42 GTPASE CYCLE 144 7.14e-04 1.63e-01 4.51e-02
REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS 111 7.47e-04 -1.85e-01 4.55e-02
REACTOME SIGNALING BY ROBO RECEPTORS 206 7.89e-04 -1.36e-01 4.63e-02
REACTOME SYNTHESIS OF LIPOXINS LX 6 8.25e-04 7.88e-01 4.67e-02
REACTOME PHOSPHOLIPID METABOLISM 201 8.55e-04 1.36e-01 4.68e-02
REACTOME RESPIRATORY ELECTRON TRANSPORT 90 1.10e-03 -1.99e-01 5.61e-02
REACTOME ELASTIC FIBRE FORMATION 44 1.13e-03 2.84e-01 5.61e-02
REACTOME RAC1 GTPASE CYCLE 172 1.13e-03 1.44e-01 5.61e-02
REACTOME CD28 CO STIMULATION 32 1.24e-03 3.30e-01 5.97e-02
REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES 39 1.28e-03 -2.98e-01 6.00e-02
REACTOME RHOA GTPASE CYCLE 142 1.52e-03 1.54e-01 6.95e-02
REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS 20 1.74e-03 4.04e-01 7.72e-02
REACTOME RHOB GTPASE CYCLE 67 1.95e-03 2.19e-01 8.42e-02
REACTOME SARS COV 1 INFECTION 136 2.11e-03 -1.53e-01 8.88e-02
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION 250 2.25e-03 1.12e-01 9.07e-02
REACTOME CELL CYCLE CHECKPOINTS 284 2.27e-03 -1.05e-01 9.07e-02
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY 33 2.32e-03 -3.06e-01 9.07e-02
REACTOME MITOCHONDRIAL TRANSLATION 93 2.38e-03 -1.82e-01 9.09e-02
REACTOME MITOTIC G2 G2 M PHASES 194 2.47e-03 -1.26e-01 9.23e-02
REACTOME NRAGE SIGNALS DEATH THROUGH JNK 53 2.58e-03 2.39e-01 9.41e-02
REACTOME INTERFERON ALPHA BETA SIGNALING 70 2.65e-03 -2.08e-01 9.46e-02
REACTOME INTERFERON SIGNALING 193 2.76e-03 -1.25e-01 9.63e-02
REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL 58 2.82e-03 -2.27e-01 9.64e-02
REACTOME HEMOSTASIS 591 3.01e-03 7.14e-02 1.01e-01
REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES 80 3.08e-03 -1.91e-01 1.01e-01
REACTOME CELLULAR RESPONSE TO STARVATION 147 3.47e-03 -1.40e-01 1.12e-01
REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION 145 3.63e-03 -1.40e-01 1.15e-01
REACTOME CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY 84 3.72e-03 -1.83e-01 1.15e-01
REACTOME PINK1 PRKN MEDIATED MITOPHAGY 22 3.98e-03 -3.55e-01 1.21e-01
REACTOME GPVI MEDIATED ACTIVATION CASCADE 35 4.07e-03 2.81e-01 1.21e-01
REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3 679 4.20e-03 6.44e-02 1.23e-01
REACTOME S PHASE 159 4.32e-03 -1.31e-01 1.24e-01
REACTOME G ALPHA I SIGNALLING EVENTS 304 4.40e-03 9.50e-02 1.24e-01
REACTOME APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS 87 4.48e-03 -1.76e-01 1.25e-01
REACTOME M PHASE 398 4.84e-03 -8.23e-02 1.33e-01
REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA 11 5.01e-03 -4.89e-01 1.35e-01
REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC 28 5.16e-03 -3.05e-01 1.37e-01
REACTOME AMINE LIGAND BINDING RECEPTORS 40 5.41e-03 2.54e-01 1.40e-01
REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL 129 5.47e-03 1.42e-01 1.40e-01
REACTOME G ALPHA 12 13 SIGNALLING EVENTS 74 5.57e-03 1.86e-01 1.41e-01
REACTOME GENERATION OF SECOND MESSENGER MOLECULES 30 5.75e-03 2.91e-01 1.41e-01
REACTOME CELLULAR RESPONSES TO STIMULI 779 5.77e-03 -5.81e-02 1.41e-01
REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES 37 6.15e-03 2.60e-01 1.48e-01
REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT 159 6.36e-03 -1.25e-01 1.51e-01
REACTOME SARS COV 2 INFECTION 281 6.52e-03 -9.43e-02 1.53e-01
REACTOME CD28 DEPENDENT PI3K AKT SIGNALING 22 6.97e-03 3.32e-01 1.61e-01
REACTOME POLO LIKE KINASE MEDIATED EVENTS 16 7.07e-03 -3.89e-01 1.61e-01
REACTOME ION CHANNEL TRANSPORT 172 7.51e-03 1.18e-01 1.69e-01
REACTOME PD 1 SIGNALING 21 7.80e-03 3.35e-01 1.73e-01
REACTOME SIGNALING BY INSULIN RECEPTOR 80 8.42e-03 1.70e-01 1.84e-01
REACTOME SEPARATION OF SISTER CHROMATIDS 184 8.53e-03 -1.12e-01 1.84e-01
REACTOME ANTIGEN PROCESSING CROSS PRESENTATION 98 8.77e-03 -1.53e-01 1.84e-01
REACTOME INTEGRIN CELL SURFACE INTERACTIONS 83 8.84e-03 1.66e-01 1.84e-01
REACTOME EFFECTS OF PIP2 HYDROLYSIS 26 8.87e-03 2.96e-01 1.84e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS 14 9.09e-03 4.03e-01 1.86e-01
REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21 59 9.19e-03 -1.96e-01 1.86e-01
REACTOME MITOTIC METAPHASE AND ANAPHASE 228 9.29e-03 -1.00e-01 1.86e-01
REACTOME ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION 16 9.62e-03 3.74e-01 1.90e-01
REACTOME SARS COV 2 ACTIVATES MODULATES INNATE AND ADAPTIVE IMMUNE RESPONSES 118 1.06e-02 -1.36e-01 2.05e-01
REACTOME REGULATION OF GENE EXPRESSION IN ENDOCRINE COMMITTED NEUROG3 PROGENITOR CELLS 5 1.07e-02 -6.59e-01 2.05e-01
REACTOME INTEGRIN SIGNALING 27 1.09e-02 2.83e-01 2.05e-01
REACTOME STRIATED MUSCLE CONTRACTION 35 1.09e-02 2.49e-01 2.05e-01
REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE 48 1.10e-02 2.12e-01 2.05e-01
REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS 11 1.12e-02 -4.42e-01 2.06e-01
REACTOME DEFENSINS 33 1.13e-02 2.55e-01 2.07e-01
REACTOME TYPE I HEMIDESMOSOME ASSEMBLY 11 1.18e-02 4.38e-01 2.13e-01
REACTOME NOTCH HLH TRANSCRIPTION PATHWAY 24 1.21e-02 2.96e-01 2.17e-01
REACTOME RAC2 GTPASE CYCLE 81 1.27e-02 1.60e-01 2.24e-01
REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS 312 1.30e-02 8.18e-02 2.25e-01
REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS 28 1.30e-02 2.71e-01 2.25e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION 29 1.42e-02 2.63e-01 2.38e-01
REACTOME REPRESSION OF WNT TARGET GENES 14 1.44e-02 3.78e-01 2.38e-01
REACTOME RAC3 GTPASE CYCLE 85 1.45e-02 1.53e-01 2.38e-01
REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS 13 1.45e-02 3.91e-01 2.38e-01
REACTOME BINDING OF TCF LEF CTNNB1 TO TARGET GENE PROMOTERS 8 1.45e-02 4.99e-01 2.38e-01
REACTOME TRANSPORT OF SMALL MOLECULES 697 1.46e-02 5.42e-02 2.38e-01
REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT 236 1.52e-02 9.17e-02 2.44e-01
REACTOME DEFECTIVE LFNG CAUSES SCDO3 5 1.61e-02 6.22e-01 2.54e-01
REACTOME FOLDING OF ACTIN BY CCT TRIC 10 1.61e-02 -4.40e-01 2.54e-01
REACTOME SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE 91 1.67e-02 -1.45e-01 2.61e-01
REACTOME MITOTIC SPINDLE CHECKPOINT 109 1.72e-02 -1.32e-01 2.66e-01
REACTOME SCAVENGING BY CLASS F RECEPTORS 6 1.75e-02 -5.60e-01 2.68e-01
REACTOME GERM LAYER FORMATION AT GASTRULATION 17 1.78e-02 3.32e-01 2.68e-01
REACTOME CYCLIN D ASSOCIATED EVENTS IN G1 46 1.78e-02 -2.02e-01 2.68e-01
REACTOME POTENTIAL THERAPEUTICS FOR SARS 92 1.83e-02 1.42e-01 2.71e-01
REACTOME ASPIRIN ADME 42 1.85e-02 -2.10e-01 2.71e-01
REACTOME SENSORY PROCESSING OF SOUND 72 1.85e-02 1.61e-01 2.71e-01
REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS 8 1.87e-02 4.80e-01 2.72e-01
REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS 123 1.94e-02 1.22e-01 2.77e-01
REACTOME TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY 16 1.95e-02 3.37e-01 2.77e-01
REACTOME COMPLEX I BIOGENESIS 49 1.95e-02 -1.93e-01 2.77e-01
REACTOME IRS MEDIATED SIGNALLING 47 1.99e-02 1.96e-01 2.80e-01
REACTOME RECYCLING OF EIF2 GDP 7 2.02e-02 -5.07e-01 2.81e-01
REACTOME TRP CHANNELS 27 2.05e-02 2.58e-01 2.81e-01
REACTOME MITOTIC PROMETAPHASE 194 2.05e-02 -9.65e-02 2.81e-01
REACTOME G ALPHA Q SIGNALLING EVENTS 206 2.13e-02 9.30e-02 2.90e-01
REACTOME SIGNALING BY RECEPTOR TYROSINE KINASES 507 2.20e-02 5.94e-02 2.95e-01
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA 263 2.26e-02 -8.17e-02 2.95e-01
REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION 9 2.26e-02 4.39e-01 2.95e-01
REACTOME CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION 24 2.27e-02 -2.69e-01 2.95e-01
REACTOME COLLAGEN FORMATION 88 2.28e-02 1.40e-01 2.95e-01
REACTOME PI METABOLISM 79 2.29e-02 1.48e-01 2.95e-01
REACTOME FCERI MEDIATED MAPK ACTIVATION 32 2.30e-02 2.32e-01 2.95e-01
REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA 28 2.32e-02 -2.48e-01 2.95e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION 27 2.41e-02 -2.51e-01 3.04e-01
REACTOME BETA DEFENSINS 27 2.50e-02 2.49e-01 3.13e-01
REACTOME RHOJ GTPASE CYCLE 51 2.53e-02 1.81e-01 3.14e-01
REACTOME DNA REPLICATION 178 2.56e-02 -9.70e-02 3.14e-01
REACTOME NEF AND SIGNAL TRANSDUCTION 8 2.61e-02 4.54e-01 3.14e-01
REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX 36 2.61e-02 2.14e-01 3.14e-01
REACTOME BIOLOGICAL OXIDATIONS 210 2.62e-02 -8.90e-02 3.14e-01
REACTOME PROTEIN LOCALIZATION 153 2.62e-02 -1.04e-01 3.14e-01
REACTOME DRUG ADME 103 2.80e-02 -1.25e-01 3.33e-01
REACTOME RAB REGULATION OF TRAFFICKING 110 2.93e-02 1.20e-01 3.46e-01
REACTOME ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS 87 2.99e-02 1.35e-01 3.48e-01
REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 73 3.00e-02 -1.47e-01 3.48e-01
REACTOME REGULATION OF MECP2 EXPRESSION AND ACTIVITY 30 3.01e-02 2.29e-01 3.48e-01
REACTOME MUSCLE CONTRACTION 197 3.04e-02 8.95e-02 3.49e-01
REACTOME RUNX3 REGULATES WNT SIGNALING 8 3.08e-02 4.41e-01 3.49e-01
REACTOME ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS 7 3.10e-02 4.71e-01 3.49e-01
REACTOME MISCELLANEOUS SUBSTRATES 12 3.12e-02 -3.59e-01 3.49e-01
REACTOME BASIGIN INTERACTIONS 24 3.13e-02 2.54e-01 3.49e-01
REACTOME CTLA4 INHIBITORY SIGNALING 21 3.17e-02 2.71e-01 3.51e-01
REACTOME CROSS PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS PHAGOSOMES 6 3.27e-02 5.04e-01 3.60e-01
REACTOME SEMAPHORIN INTERACTIONS 61 3.29e-02 1.58e-01 3.60e-01
REACTOME ORC1 REMOVAL FROM CHROMATIN 70 3.33e-02 -1.47e-01 3.62e-01
REACTOME SIGNALING BY ACTIVIN 15 3.39e-02 3.16e-01 3.66e-01
REACTOME PLATELET AGGREGATION PLUG FORMATION 39 3.42e-02 1.96e-01 3.67e-01
REACTOME REGULATION OF SIGNALING BY NODAL 9 3.45e-02 4.07e-01 3.67e-01
REACTOME PECAM1 INTERACTIONS 12 3.46e-02 3.52e-01 3.67e-01
REACTOME MEIOTIC RECOMBINATION 80 3.51e-02 -1.36e-01 3.69e-01
REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE 69 3.60e-02 1.46e-01 3.76e-01
REACTOME INSULIN RECEPTOR SIGNALLING CASCADE 53 3.63e-02 1.66e-01 3.77e-01
REACTOME TACHYKININ RECEPTORS BIND TACHYKININS 5 3.73e-02 -5.38e-01 3.85e-01
REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK 28 3.77e-02 2.27e-01 3.87e-01
REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS 9 3.85e-02 3.98e-01 3.91e-01
REACTOME MRNA SPLICING 197 3.86e-02 -8.55e-02 3.91e-01
REACTOME RESOLUTION OF SISTER CHROMATID COHESION 120 3.92e-02 -1.09e-01 3.95e-01
REACTOME ION TRANSPORT BY P TYPE ATPASES 51 3.97e-02 1.66e-01 3.98e-01
REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS 21 4.09e-02 -2.58e-01 4.07e-01
REACTOME SIGNALING BY SCF KIT 42 4.14e-02 1.82e-01 4.09e-01
REACTOME HEME SIGNALING 47 4.16e-02 1.72e-01 4.09e-01
REACTOME INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES 28 4.22e-02 -2.22e-01 4.11e-01
REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING 30 4.23e-02 2.14e-01 4.11e-01
REACTOME LOSS OF FUNCTION OF SMAD2 3 IN CANCER 7 4.30e-02 4.42e-01 4.14e-01
REACTOME OLFACTORY SIGNALING PATHWAY 348 4.31e-02 -6.31e-02 4.14e-01
REACTOME POTASSIUM CHANNELS 102 4.34e-02 1.16e-01 4.14e-01
REACTOME RNA POLYMERASE I PROMOTER ESCAPE 83 4.43e-02 -1.28e-01 4.20e-01
REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION 12 4.50e-02 3.34e-01 4.20e-01
REACTOME AURKA ACTIVATION BY TPX2 69 4.50e-02 -1.40e-01 4.20e-01
REACTOME HEME BIOSYNTHESIS 13 4.51e-02 -3.21e-01 4.20e-01
REACTOME TRIGLYCERIDE METABOLISM 35 4.55e-02 1.95e-01 4.20e-01
REACTOME SIGNALING BY VEGF 102 4.56e-02 1.15e-01 4.20e-01
REACTOME VXPX CARGO TARGETING TO CILIUM 20 4.65e-02 2.57e-01 4.20e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS 9 4.68e-02 3.83e-01 4.20e-01
REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS 19 4.70e-02 2.63e-01 4.20e-01
REACTOME SARS COV INFECTIONS 392 4.76e-02 -5.83e-02 4.20e-01
REACTOME BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA 5 4.78e-02 -5.11e-01 4.20e-01
REACTOME RETINOID CYCLE DISEASE EVENTS 11 4.80e-02 3.44e-01 4.20e-01
REACTOME MITOPHAGY 28 4.87e-02 -2.15e-01 4.20e-01
REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A 26 4.87e-02 -2.23e-01 4.20e-01
REACTOME OAS ANTIVIRAL RESPONSE 8 4.88e-02 -4.02e-01 4.20e-01
REACTOME ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES 59 4.90e-02 1.48e-01 4.20e-01
REACTOME GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION 30 4.91e-02 -2.08e-01 4.20e-01
REACTOME MYOGENESIS 29 4.92e-02 2.11e-01 4.20e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS 7 4.93e-02 4.29e-01 4.20e-01
REACTOME RHO GTPASES ACTIVATE NADPH OXIDASES 21 4.94e-02 2.48e-01 4.20e-01
REACTOME AMINO ACID CONJUGATION 9 4.94e-02 -3.78e-01 4.20e-01
REACTOME INFLAMMASOMES 21 5.01e-02 -2.47e-01 4.20e-01
REACTOME SCAVENGING OF HEME FROM PLASMA 13 5.02e-02 3.14e-01 4.20e-01
REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS 418 5.03e-02 5.58e-02 4.20e-01
REACTOME MUCOPOLYSACCHARIDOSES 10 5.07e-02 3.57e-01 4.20e-01
REACTOME GPCR LIGAND BINDING 444 5.09e-02 5.40e-02 4.20e-01
REACTOME DNA REPAIR 321 5.10e-02 -6.34e-02 4.20e-01
REACTOME EPHRIN SIGNALING 17 5.12e-02 2.73e-01 4.20e-01
REACTOME TRNA MODIFICATION IN THE MITOCHONDRION 8 5.18e-02 -3.97e-01 4.22e-01
REACTOME DEATH RECEPTOR SIGNALING 143 5.21e-02 9.41e-02 4.22e-01
REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS 63 5.24e-02 1.41e-01 4.22e-01
REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING 30 5.25e-02 2.05e-01 4.22e-01
REACTOME REPRODUCTION 136 5.28e-02 -9.62e-02 4.23e-01
REACTOME G PROTEIN BETA GAMMA SIGNALLING 30 5.37e-02 2.03e-01 4.24e-01
REACTOME DISEASES OF MITOTIC CELL CYCLE 37 5.38e-02 -1.83e-01 4.24e-01
REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING 89 5.40e-02 1.18e-01 4.24e-01
REACTOME CHYLOMICRON CLEARANCE 5 5.40e-02 4.98e-01 4.24e-01
REACTOME MITOCHONDRIAL PROTEIN IMPORT 58 5.48e-02 -1.46e-01 4.28e-01
REACTOME G1 S SPECIFIC TRANSCRIPTION 28 5.58e-02 -2.09e-01 4.33e-01
REACTOME G2 M CHECKPOINTS 162 5.60e-02 -8.70e-02 4.33e-01
REACTOME RHOQ GTPASE CYCLE 57 5.63e-02 1.46e-01 4.33e-01
REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE 15 5.67e-02 2.84e-01 4.33e-01
REACTOME DNA REPLICATION PRE INITIATION 150 5.71e-02 -9.00e-02 4.33e-01
REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R 52 5.72e-02 1.52e-01 4.33e-01
REACTOME O LINKED GLYCOSYLATION OF MUCINS 61 5.74e-02 1.41e-01 4.33e-01
REACTOME REGULATION OF KIT SIGNALING 16 5.76e-02 2.74e-01 4.33e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1 16 5.82e-02 -2.74e-01 4.36e-01
REACTOME PI 3K CASCADE FGFR4 19 5.84e-02 2.51e-01 4.36e-01
REACTOME CELL CELL COMMUNICATION 126 5.93e-02 9.73e-02 4.39e-01
REACTOME CRMPS IN SEMA3A SIGNALING 15 5.94e-02 2.81e-01 4.39e-01
REACTOME RHOC GTPASE CYCLE 71 6.14e-02 1.28e-01 4.49e-01
REACTOME RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION 6 6.14e-02 4.41e-01 4.49e-01
REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS 12 6.16e-02 3.12e-01 4.49e-01
REACTOME INTERLEUKIN RECEPTOR SHC SIGNALING 24 6.21e-02 2.20e-01 4.49e-01
REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN 19 6.25e-02 -2.47e-01 4.49e-01
REACTOME CARGO CONCENTRATION IN THE ER 32 6.26e-02 -1.90e-01 4.49e-01
REACTOME COMPLEMENT CASCADE 54 6.29e-02 -1.46e-01 4.49e-01
REACTOME PI3K AKT SIGNALING IN CANCER 103 6.29e-02 1.06e-01 4.49e-01
REACTOME ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS 17 6.38e-02 -2.60e-01 4.53e-01
REACTOME INTERLEUKIN 2 SIGNALING 11 6.44e-02 3.22e-01 4.55e-01
REACTOME SYNTHESIS OF DNA 119 6.47e-02 -9.80e-02 4.55e-01
REACTOME REGULATION OF BETA CELL DEVELOPMENT 41 6.48e-02 -1.67e-01 4.55e-01
REACTOME CRISTAE FORMATION 27 6.58e-02 -2.05e-01 4.60e-01
REACTOME CD28 DEPENDENT VAV1 PATHWAY 11 6.67e-02 3.19e-01 4.64e-01
REACTOME POST TRANSCRIPTIONAL SILENCING BY SMALL RNAS 7 6.74e-02 3.99e-01 4.67e-01
REACTOME ACETYLCHOLINE REGULATES INSULIN SECRETION 10 6.87e-02 3.32e-01 4.74e-01
REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING 13 6.91e-02 2.91e-01 4.75e-01
REACTOME DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA 77 7.02e-02 -1.19e-01 4.77e-01
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES 55 7.03e-02 1.41e-01 4.77e-01
REACTOME INOSITOL PHOSPHATE METABOLISM 45 7.03e-02 1.56e-01 4.77e-01
REACTOME ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS 20 7.05e-02 -2.34e-01 4.77e-01
REACTOME ADAPTIVE IMMUNE SYSTEM 729 7.16e-02 3.92e-02 4.81e-01
REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX 134 7.17e-02 9.01e-02 4.81e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR4 14 7.25e-02 2.77e-01 4.84e-01
REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS 15 7.30e-02 2.67e-01 4.85e-01
REACTOME VOLTAGE GATED POTASSIUM CHANNELS 42 7.56e-02 1.58e-01 4.98e-01
REACTOME NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION 193 7.57e-02 7.42e-02 4.98e-01
REACTOME REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION 84 7.59e-02 -1.12e-01 4.98e-01
REACTOME FORMATION OF TC NER PRE INCISION COMPLEX 51 7.61e-02 -1.44e-01 4.98e-01
REACTOME DAP12 SIGNALING 27 7.66e-02 1.97e-01 4.99e-01
REACTOME RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION 8 7.83e-02 3.59e-01 5.08e-01
REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY 5 7.85e-02 4.54e-01 5.08e-01
REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS 11 7.92e-02 -3.06e-01 5.09e-01
REACTOME HDL CLEARANCE 5 7.93e-02 4.53e-01 5.09e-01
REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION 62 8.06e-02 -1.28e-01 5.12e-01
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES 255 8.08e-02 6.35e-02 5.12e-01
REACTOME ER TO GOLGI ANTEROGRADE TRANSPORT 152 8.10e-02 -8.20e-02 5.12e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FYN 7 8.10e-02 3.81e-01 5.12e-01
REACTOME THE NLRP3 INFLAMMASOME 16 8.22e-02 -2.51e-01 5.17e-01
REACTOME ONCOGENIC MAPK SIGNALING 79 8.26e-02 1.13e-01 5.18e-01
REACTOME FORMATION OF AXIAL MESODERM 14 8.35e-02 2.67e-01 5.19e-01
REACTOME HDL REMODELING 10 8.38e-02 3.16e-01 5.19e-01
REACTOME MAPK FAMILY SIGNALING CASCADES 314 8.38e-02 5.67e-02 5.19e-01
REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH 62 8.40e-02 1.27e-01 5.19e-01
REACTOME MISCELLANEOUS TRANSPORT AND BINDING EVENTS 24 8.44e-02 -2.03e-01 5.19e-01
REACTOME NEPHRIN FAMILY INTERACTIONS 22 8.50e-02 2.12e-01 5.21e-01
REACTOME ENDOSOMAL VACUOLAR PATHWAY 11 8.59e-02 -2.99e-01 5.22e-01
REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 100 8.61e-02 -9.93e-02 5.22e-01
REACTOME RHOH GTPASE CYCLE 37 8.64e-02 1.63e-01 5.22e-01
REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION 13 8.67e-02 -2.74e-01 5.22e-01
REACTOME G1 S DNA DAMAGE CHECKPOINTS 67 8.70e-02 -1.21e-01 5.22e-01
REACTOME G0 AND EARLY G1 27 8.74e-02 -1.90e-01 5.22e-01
REACTOME NEURONAL SYSTEM 388 8.74e-02 5.05e-02 5.22e-01
REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK 111 8.83e-02 9.37e-02 5.25e-01
REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4 33 8.91e-02 1.71e-01 5.28e-01
REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS 6 9.04e-02 -3.99e-01 5.34e-01
REACTOME PARACETAMOL ADME 26 9.11e-02 -1.91e-01 5.36e-01
REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE 22 9.18e-02 -2.08e-01 5.39e-01
REACTOME REGULATION OF TP53 ACTIVITY 156 9.24e-02 7.81e-02 5.39e-01
REACTOME ACTIVATION OF BH3 ONLY PROTEINS 30 9.26e-02 1.77e-01 5.39e-01
REACTOME INTERLEUKIN 2 FAMILY SIGNALING 40 9.29e-02 1.54e-01 5.39e-01
REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS 35 9.34e-02 1.64e-01 5.40e-01
REACTOME FREE FATTY ACIDS REGULATE INSULIN SECRETION 10 9.43e-02 3.06e-01 5.43e-01
REACTOME BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA 6 9.45e-02 -3.94e-01 5.43e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION TERMINATION 30 9.58e-02 -1.76e-01 5.44e-01
REACTOME GDP FUCOSE BIOSYNTHESIS 6 9.58e-02 3.93e-01 5.44e-01
REACTOME G ALPHA Z SIGNALLING EVENTS 48 9.61e-02 1.39e-01 5.44e-01
REACTOME FCERI MEDIATED CA 2 MOBILIZATION 30 9.66e-02 1.75e-01 5.44e-01
REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS 60 9.66e-02 -1.24e-01 5.44e-01
REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 54 9.68e-02 -1.31e-01 5.44e-01
REACTOME CD22 MEDIATED BCR REGULATION 5 9.76e-02 4.28e-01 5.46e-01
REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE 9 9.81e-02 -3.18e-01 5.46e-01
REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS 83 9.82e-02 1.05e-01 5.46e-01
REACTOME KERATINIZATION 210 9.84e-02 -6.62e-02 5.46e-01
REACTOME TRIGLYCERIDE CATABOLISM 23 9.89e-02 1.99e-01 5.47e-01
REACTOME PARASITE INFECTION 57 9.94e-02 1.26e-01 5.47e-01
REACTOME TRNA PROCESSING 105 1.00e-01 -9.29e-02 5.47e-01
REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY 26 1.01e-01 1.86e-01 5.47e-01
REACTOME SNRNP ASSEMBLY 53 1.01e-01 -1.30e-01 5.47e-01
REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT 99 1.01e-01 -9.54e-02 5.47e-01
REACTOME SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA PHE 6 1.01e-01 -3.86e-01 5.47e-01
REACTOME TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS 82 1.03e-01 1.04e-01 5.47e-01
REACTOME ECM PROTEOGLYCANS 73 1.03e-01 1.10e-01 5.47e-01
REACTOME INTERLEUKIN 10 SIGNALING 43 1.03e-01 1.44e-01 5.47e-01
REACTOME INFECTIOUS DISEASE 910 1.04e-01 -3.18e-02 5.47e-01
REACTOME METABOLISM OF POLYAMINES 56 1.04e-01 -1.26e-01 5.47e-01
REACTOME CONDENSATION OF PROPHASE CHROMOSOMES 66 1.04e-01 -1.16e-01 5.47e-01
REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING 32 1.04e-01 1.66e-01 5.47e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING 5 1.05e-01 4.19e-01 5.47e-01
REACTOME FRS MEDIATED FGFR4 SIGNALING 21 1.05e-01 2.05e-01 5.47e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA 25 1.05e-01 1.87e-01 5.47e-01
REACTOME RHOU GTPASE CYCLE 37 1.05e-01 1.54e-01 5.47e-01
REACTOME IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS 17 1.05e-01 -2.27e-01 5.47e-01
REACTOME SUMOYLATION OF TRANSCRIPTION FACTORS 20 1.05e-01 2.09e-01 5.48e-01
REACTOME O LINKED GLYCOSYLATION 109 1.06e-01 8.97e-02 5.48e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX IN CANCER 8 1.07e-01 3.29e-01 5.50e-01
REACTOME ION HOMEOSTASIS 52 1.07e-01 1.29e-01 5.50e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS 121 1.07e-01 -8.48e-02 5.50e-01
REACTOME CHROMOSOME MAINTENANCE 130 1.08e-01 -8.17e-02 5.50e-01
REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES 34 1.08e-01 1.59e-01 5.50e-01
REACTOME NS1 MEDIATED EFFECTS ON HOST PATHWAYS 41 1.09e-01 -1.45e-01 5.50e-01
REACTOME P2Y RECEPTORS 9 1.09e-01 3.09e-01 5.50e-01
REACTOME LIPID PARTICLE ORGANIZATION 6 1.09e-01 -3.77e-01 5.50e-01
REACTOME P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1 6 1.09e-01 3.77e-01 5.50e-01
REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL 13 1.10e-01 2.56e-01 5.50e-01
REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES 78 1.11e-01 -1.05e-01 5.50e-01
REACTOME P75NTR REGULATES AXONOGENESIS 9 1.11e-01 3.07e-01 5.50e-01
REACTOME MAPK1 ERK2 ACTIVATION 9 1.11e-01 3.07e-01 5.50e-01
REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX 39 1.11e-01 1.47e-01 5.50e-01
REACTOME ETHANOL OXIDATION 12 1.12e-01 -2.65e-01 5.50e-01
REACTOME MATURATION OF SARS COV 2 SPIKE PROTEIN 35 1.12e-01 1.55e-01 5.50e-01
REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES 101 1.12e-01 9.15e-02 5.51e-01
REACTOME AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA 54 1.13e-01 -1.25e-01 5.52e-01
REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING 33 1.13e-01 1.59e-01 5.52e-01
REACTOME METABOLISM OF NUCLEOTIDES 94 1.13e-01 -9.45e-02 5.52e-01
REACTOME SYNTHESIS OF PI 5 1.14e-01 4.08e-01 5.52e-01
REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION 74 1.15e-01 1.06e-01 5.55e-01
REACTOME OPSINS 7 1.16e-01 3.43e-01 5.61e-01
REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE 93 1.17e-01 -9.42e-02 5.61e-01
REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS 21 1.17e-01 -1.98e-01 5.61e-01
REACTOME HYDROLYSIS OF LPC 9 1.18e-01 3.01e-01 5.62e-01
REACTOME LYSOSOME VESICLE BIOGENESIS 33 1.18e-01 1.57e-01 5.62e-01
REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS 37 1.19e-01 -1.48e-01 5.62e-01
REACTOME DNA REPLICATION INITIATION 7 1.19e-01 3.41e-01 5.62e-01
REACTOME RIP MEDIATED NFKB ACTIVATION VIA ZBP1 16 1.19e-01 -2.25e-01 5.62e-01
REACTOME CREATION OF C4 AND C2 ACTIVATORS 14 1.21e-01 -2.39e-01 5.72e-01
REACTOME FGFR2 LIGAND BINDING AND ACTIVATION 19 1.22e-01 2.05e-01 5.72e-01
REACTOME SYNTHESIS OF 5 EICOSATETRAENOIC ACIDS 9 1.23e-01 2.97e-01 5.73e-01
REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS 15 1.23e-01 2.30e-01 5.73e-01
REACTOME NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 11 1.23e-01 2.69e-01 5.73e-01
REACTOME PHASE 2 PLATEAU PHASE 14 1.23e-01 2.38e-01 5.73e-01
REACTOME REGULATION OF INSULIN SECRETION 77 1.24e-01 1.01e-01 5.73e-01
REACTOME COPI MEDIATED ANTEROGRADE TRANSPORT 101 1.24e-01 -8.86e-02 5.73e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING 25 1.24e-01 1.78e-01 5.74e-01
REACTOME STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES 16 1.26e-01 -2.21e-01 5.79e-01
REACTOME NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 24 1.26e-01 1.80e-01 5.79e-01
REACTOME TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER 76 1.27e-01 -1.01e-01 5.79e-01
REACTOME NEF MEDIATED CD4 DOWN REGULATION 9 1.27e-01 2.94e-01 5.79e-01
REACTOME MET ACTIVATES RAP1 AND RAC1 11 1.28e-01 2.65e-01 5.79e-01
REACTOME RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS 9 1.28e-01 -2.93e-01 5.79e-01
REACTOME RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION 6 1.28e-01 3.59e-01 5.79e-01
REACTOME ACYL CHAIN REMODELING OF DAG AND TAG 5 1.29e-01 3.92e-01 5.80e-01
REACTOME MTOR SIGNALLING 40 1.29e-01 1.39e-01 5.82e-01
REACTOME INWARDLY RECTIFYING K CHANNELS 35 1.30e-01 1.48e-01 5.82e-01
REACTOME DRUG MEDIATED INHIBITION OF CDK4 CDK6 ACTIVITY 5 1.30e-01 -3.91e-01 5.82e-01
REACTOME INSULIN PROCESSING 24 1.30e-01 1.78e-01 5.82e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS 7 1.31e-01 -3.30e-01 5.82e-01
REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION 9 1.32e-01 -2.90e-01 5.86e-01
REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING 16 1.34e-01 -2.16e-01 5.90e-01
REACTOME MRNA SPLICING MINOR PATHWAY 49 1.35e-01 -1.24e-01 5.90e-01
REACTOME SIGNALING BY FGFR4 40 1.36e-01 1.36e-01 5.90e-01
REACTOME NR1H2 AND NR1H3 MEDIATED SIGNALING 46 1.37e-01 1.27e-01 5.90e-01
REACTOME CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA 63 1.37e-01 -1.08e-01 5.90e-01
REACTOME PI 3K CASCADE FGFR1 21 1.37e-01 1.88e-01 5.90e-01
REACTOME RUNX3 REGULATES YAP1 MEDIATED TRANSCRIPTION 8 1.37e-01 3.03e-01 5.90e-01
REACTOME MELANIN BIOSYNTHESIS 5 1.37e-01 -3.84e-01 5.90e-01
REACTOME FATTY ACIDS BOUND TO GPR40 FFAR1 REGULATE INSULIN SECRETION 8 1.38e-01 3.03e-01 5.90e-01
REACTOME EICOSANOIDS 12 1.38e-01 -2.47e-01 5.90e-01
REACTOME MATURATION OF PROTEIN 3A 9 1.38e-01 2.86e-01 5.90e-01
REACTOME METABOLISM OF STEROID HORMONES 35 1.38e-01 -1.45e-01 5.90e-01
REACTOME LEISHMANIA INFECTION 156 1.38e-01 6.87e-02 5.90e-01
REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS 299 1.39e-01 4.98e-02 5.90e-01
REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING 28 1.39e-01 1.62e-01 5.90e-01
REACTOME CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER 25 1.39e-01 1.71e-01 5.90e-01
REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING 45 1.39e-01 1.27e-01 5.90e-01
REACTOME NTRK2 ACTIVATES RAC1 5 1.39e-01 3.82e-01 5.90e-01
REACTOME TRANSCRIPTIONAL REGULATION BY E2F6 32 1.40e-01 -1.51e-01 5.90e-01
REACTOME EARLY PHASE OF HIV LIFE CYCLE 14 1.40e-01 -2.28e-01 5.90e-01
REACTOME NICOTINATE METABOLISM 31 1.41e-01 1.53e-01 5.93e-01
REACTOME CARDIAC CONDUCTION 125 1.42e-01 7.60e-02 5.95e-01
REACTOME SYNTHESIS OF PC 27 1.42e-01 1.63e-01 5.95e-01
REACTOME DEFECTIVE CSF2RB CAUSES SMDP5 7 1.43e-01 -3.19e-01 5.97e-01
REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS 21 1.44e-01 -1.84e-01 5.99e-01
REACTOME RUNX3 REGULATES CDKN1A TRANSCRIPTION 7 1.45e-01 3.18e-01 6.01e-01
REACTOME FERTILIZATION 26 1.47e-01 -1.64e-01 6.07e-01
REACTOME COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC 98 1.47e-01 -8.47e-02 6.07e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS 11 1.48e-01 -2.52e-01 6.07e-01
REACTOME STIMULI SENSING CHANNELS 100 1.48e-01 8.37e-02 6.07e-01
REACTOME MEIOSIS 110 1.48e-01 -7.98e-02 6.07e-01
REACTOME CHOLESTEROL BIOSYNTHESIS 25 1.49e-01 -1.67e-01 6.07e-01
REACTOME SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS 43 1.49e-01 1.27e-01 6.08e-01
REACTOME PHASE II CONJUGATION OF COMPOUNDS 102 1.50e-01 -8.25e-02 6.08e-01
REACTOME ADRENOCEPTORS 9 1.50e-01 2.77e-01 6.08e-01
REACTOME COPII MEDIATED VESICLE TRANSPORT 66 1.51e-01 -1.02e-01 6.10e-01
REACTOME REGULATION OF NPAS4 GENE EXPRESSION 13 1.51e-01 2.30e-01 6.10e-01
REACTOME PI 3K CASCADE FGFR2 22 1.52e-01 1.77e-01 6.10e-01
REACTOME GABA B RECEPTOR ACTIVATION 43 1.53e-01 1.26e-01 6.15e-01
REACTOME THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT 77 1.55e-01 -9.36e-02 6.23e-01
REACTOME VITAMIN B1 THIAMIN METABOLISM 5 1.57e-01 -3.65e-01 6.29e-01
REACTOME COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES 65 1.58e-01 1.01e-01 6.30e-01
REACTOME RSK ACTIVATION 5 1.59e-01 3.64e-01 6.32e-01
REACTOME ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS 24 1.60e-01 1.66e-01 6.34e-01
REACTOME RHOG GTPASE CYCLE 71 1.60e-01 9.64e-02 6.34e-01
REACTOME PROLONGED ERK ACTIVATION EVENTS 14 1.62e-01 2.16e-01 6.38e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA 27 1.62e-01 -1.55e-01 6.38e-01
REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B 24 1.63e-01 -1.64e-01 6.40e-01
REACTOME HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR IN THE PRESENCE OF LIGAND 55 1.64e-01 -1.08e-01 6.43e-01
REACTOME SUMOYLATION OF RNA BINDING PROTEINS 47 1.64e-01 -1.17e-01 6.43e-01
REACTOME RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES TREGS 9 1.66e-01 2.66e-01 6.46e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS 6 1.67e-01 -3.26e-01 6.46e-01
REACTOME PTK6 REGULATES CELL CYCLE 6 1.67e-01 -3.26e-01 6.46e-01
REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER 77 1.67e-01 9.11e-02 6.47e-01
REACTOME SIGNALING BY LEPTIN 11 1.68e-01 -2.40e-01 6.50e-01
REACTOME UB SPECIFIC PROCESSING PROTEASES 187 1.69e-01 -5.84e-02 6.50e-01
REACTOME THE ACTIVATION OF ARYLSULFATASES 8 1.69e-01 -2.81e-01 6.51e-01
REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY 72 1.70e-01 -9.35e-02 6.53e-01
REACTOME DISEASES ASSOCIATED WITH SURFACTANT METABOLISM 9 1.70e-01 -2.64e-01 6.53e-01
REACTOME ABC TRANSPORTER DISORDERS 76 1.73e-01 -9.05e-02 6.55e-01
REACTOME CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT 19 1.74e-01 -1.80e-01 6.55e-01
REACTOME SIGNALING BY EGFR 49 1.74e-01 1.12e-01 6.55e-01
REACTOME RUNX3 REGULATES BCL2L11 BIM TRANSCRIPTION 5 1.75e-01 3.51e-01 6.55e-01
REACTOME TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7 12 1.75e-01 -2.26e-01 6.55e-01
REACTOME SIGNALING BY FGFR2 IN DISEASE 42 1.75e-01 1.21e-01 6.55e-01
REACTOME RHOV GTPASE CYCLE 36 1.76e-01 1.30e-01 6.55e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES 49 1.76e-01 -1.12e-01 6.55e-01
REACTOME MET ACTIVATES PI3K AKT SIGNALING 6 1.76e-01 3.19e-01 6.55e-01
REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP 104 1.76e-01 -7.68e-02 6.55e-01
REACTOME FGFR1 LIGAND BINDING AND ACTIVATION 15 1.76e-01 2.02e-01 6.55e-01
REACTOME ASPARAGINE N LINKED GLYCOSYLATION 299 1.76e-01 -4.54e-02 6.55e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES 33 1.77e-01 -1.36e-01 6.55e-01
REACTOME CATION COUPLED CHLORIDE COTRANSPORTERS 7 1.77e-01 2.95e-01 6.55e-01
REACTOME P75NTR SIGNALS VIA NF KB 15 1.77e-01 -2.01e-01 6.55e-01
REACTOME REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS 11 1.79e-01 2.34e-01 6.59e-01
REACTOME INTEGRATION OF PROVIRUS 9 1.79e-01 -2.59e-01 6.59e-01
REACTOME ESTROGEN BIOSYNTHESIS 6 1.80e-01 -3.16e-01 6.60e-01
REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS 101 1.80e-01 -7.71e-02 6.61e-01
REACTOME SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA 52 1.81e-01 1.07e-01 6.61e-01
REACTOME RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS 5 1.83e-01 3.44e-01 6.65e-01
REACTOME INTEGRATION OF ENERGY METABOLISM 105 1.83e-01 7.52e-02 6.65e-01
REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION 84 1.83e-01 -8.40e-02 6.65e-01
REACTOME DEX H BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION 7 1.84e-01 -2.90e-01 6.65e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES 11 1.85e-01 -2.31e-01 6.65e-01
REACTOME SYNTHESIS OF PIPS AT THE ER MEMBRANE 5 1.85e-01 3.43e-01 6.65e-01
REACTOME PI 3K CASCADE FGFR3 17 1.85e-01 1.86e-01 6.65e-01
REACTOME CELLULAR RESPONSE TO HYPOXIA 74 1.86e-01 -8.89e-02 6.69e-01
REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES 91 1.87e-01 -8.00e-02 6.70e-01
REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS 53 1.87e-01 -1.05e-01 6.70e-01
REACTOME GLYCOGEN STORAGE DISEASES 15 1.88e-01 -1.96e-01 6.70e-01
REACTOME SIGNALING BY MRAS COMPLEX MUTANTS 7 1.88e-01 2.87e-01 6.70e-01
REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS 86 1.89e-01 -8.20e-02 6.70e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION 102 1.89e-01 -7.53e-02 6.70e-01
REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC 26 1.90e-01 -1.48e-01 6.70e-01
REACTOME SYNTHESIS OF PA 38 1.90e-01 1.23e-01 6.70e-01
REACTOME SUMOYLATION OF IMMUNE RESPONSE PROTEINS 10 1.90e-01 2.39e-01 6.70e-01
REACTOME DEFECTS IN COBALAMIN B12 METABOLISM 13 1.91e-01 2.10e-01 6.70e-01
REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION 62 1.94e-01 -9.54e-02 6.78e-01
REACTOME INTERLEUKIN 23 SIGNALING 9 1.94e-01 2.50e-01 6.78e-01
REACTOME REGULATION OF TP53 EXPRESSION AND DEGRADATION 37 1.95e-01 1.23e-01 6.80e-01
REACTOME INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION 21 1.95e-01 1.63e-01 6.80e-01
REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS 29 1.96e-01 1.39e-01 6.80e-01
REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT 15 1.96e-01 1.93e-01 6.80e-01
REACTOME CELLULAR HEXOSE TRANSPORT 21 1.97e-01 1.63e-01 6.80e-01
REACTOME ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA 9 1.97e-01 2.48e-01 6.80e-01
REACTOME BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA 5 1.98e-01 -3.33e-01 6.80e-01
REACTOME REGULATION OF PTEN MRNA TRANSLATION 9 1.98e-01 2.48e-01 6.80e-01
REACTOME CA2 PATHWAY 62 1.98e-01 9.44e-02 6.80e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE GIP 12 1.98e-01 -2.14e-01 6.80e-01
REACTOME DISEASES OF DNA REPAIR 51 2.00e-01 -1.04e-01 6.81e-01
REACTOME FGFR2B LIGAND BINDING AND ACTIVATION 10 2.00e-01 2.34e-01 6.81e-01
REACTOME BIOTIN TRANSPORT AND METABOLISM 10 2.00e-01 -2.34e-01 6.81e-01
REACTOME REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE 81 2.01e-01 -8.22e-02 6.81e-01
REACTOME MAP2K AND MAPK ACTIVATION 38 2.01e-01 1.20e-01 6.81e-01
REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING 34 2.01e-01 -1.27e-01 6.81e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR4 26 2.02e-01 1.44e-01 6.82e-01
REACTOME PRE NOTCH PROCESSING IN GOLGI 18 2.03e-01 1.73e-01 6.82e-01
REACTOME MITOTIC PROPHASE 134 2.03e-01 -6.37e-02 6.82e-01
REACTOME TBC RABGAPS 40 2.03e-01 -1.16e-01 6.82e-01
REACTOME ARACHIDONATE PRODUCTION FROM DAG 5 2.05e-01 3.28e-01 6.85e-01
REACTOME NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY 6 2.05e-01 2.99e-01 6.85e-01
REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE 66 2.05e-01 -9.02e-02 6.85e-01
REACTOME RORA ACTIVATES GENE EXPRESSION 17 2.06e-01 1.77e-01 6.85e-01
REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION 183 2.07e-01 -5.41e-02 6.86e-01
REACTOME SHC MEDIATED CASCADE FGFR4 19 2.07e-01 1.67e-01 6.86e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2 17 2.07e-01 1.77e-01 6.87e-01
REACTOME INTERLEUKIN 6 FAMILY SIGNALING 24 2.08e-01 -1.48e-01 6.88e-01
REACTOME INFECTION WITH MYCOBACTERIUM TUBERCULOSIS 25 2.09e-01 -1.45e-01 6.88e-01
REACTOME PYRIMIDINE CATABOLISM 12 2.09e-01 2.09e-01 6.89e-01
REACTOME RHOBTB3 ATPASE CYCLE 8 2.10e-01 2.56e-01 6.89e-01
REACTOME FRS MEDIATED FGFR1 SIGNALING 23 2.10e-01 1.51e-01 6.89e-01
REACTOME TRANSCRIPTIONAL REGULATION BY VENTX 41 2.11e-01 1.13e-01 6.89e-01
REACTOME METABOLISM OF PORPHYRINS 26 2.11e-01 -1.42e-01 6.89e-01
REACTOME SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL 25 2.14e-01 1.44e-01 6.93e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX 19 2.14e-01 -1.65e-01 6.93e-01
REACTOME INSULIN RECEPTOR RECYCLING 29 2.14e-01 1.33e-01 6.93e-01
REACTOME MUSCARINIC ACETYLCHOLINE RECEPTORS 5 2.14e-01 3.21e-01 6.93e-01
REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS 17 2.15e-01 -1.74e-01 6.93e-01
REACTOME NEUROTRANSMITTER CLEARANCE 9 2.15e-01 2.39e-01 6.93e-01
REACTOME SUMOYLATION OF INTRACELLULAR RECEPTORS 29 2.15e-01 1.33e-01 6.93e-01
REACTOME REGULATION OF NPAS4 MRNA TRANSLATION 9 2.16e-01 2.38e-01 6.93e-01
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION 361 2.16e-01 -3.79e-02 6.93e-01
REACTOME LDL REMODELING 6 2.17e-01 2.91e-01 6.94e-01
REACTOME FCGR3A MEDIATED IL10 SYNTHESIS 36 2.17e-01 1.19e-01 6.94e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST 14 2.18e-01 -1.90e-01 6.94e-01
REACTOME RHO GTPASES ACTIVATE IQGAPS 31 2.18e-01 1.28e-01 6.94e-01
REACTOME RELAXIN RECEPTORS 8 2.19e-01 -2.51e-01 6.94e-01
REACTOME SIGNALING BY NOTCH1 69 2.19e-01 8.55e-02 6.94e-01
REACTOME FGFR1C LIGAND BINDING AND ACTIVATION 11 2.20e-01 2.14e-01 6.94e-01
REACTOME TRANSPORT OF RCBL WITHIN THE BODY 8 2.20e-01 2.51e-01 6.94e-01
REACTOME RECYCLING PATHWAY OF L1 43 2.21e-01 1.08e-01 6.94e-01
REACTOME MET ACTIVATES PTPN11 5 2.22e-01 3.15e-01 6.94e-01
REACTOME TELOMERE EXTENSION BY TELOMERASE 22 2.22e-01 -1.50e-01 6.94e-01
REACTOME PROTON COUPLED MONOCARBOXYLATE TRANSPORT 6 2.23e-01 2.87e-01 6.94e-01
REACTOME STABILIZATION OF P53 56 2.23e-01 -9.42e-02 6.94e-01
REACTOME DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE 76 2.23e-01 -8.08e-02 6.94e-01
REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION 42 2.23e-01 1.09e-01 6.94e-01
REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION 11 2.24e-01 2.12e-01 6.94e-01
REACTOME UREA CYCLE 9 2.24e-01 -2.34e-01 6.94e-01
REACTOME RAS PROCESSING 22 2.24e-01 -1.50e-01 6.94e-01
REACTOME INTERLEUKIN 18 SIGNALING 8 2.25e-01 2.48e-01 6.94e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION 36 2.26e-01 -1.17e-01 6.94e-01
REACTOME PEPTIDE HORMONE BIOSYNTHESIS 13 2.26e-01 1.94e-01 6.94e-01
REACTOME AMINO ACIDS REGULATE MTORC1 53 2.26e-01 9.61e-02 6.94e-01
REACTOME GASTRULATION 49 2.26e-01 9.99e-02 6.94e-01
REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES 46 2.27e-01 -1.03e-01 6.94e-01
REACTOME FRS MEDIATED FGFR2 SIGNALING 24 2.27e-01 1.42e-01 6.94e-01
REACTOME SIGNALING BY PDGF 57 2.27e-01 9.24e-02 6.94e-01
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL 122 2.28e-01 6.32e-02 6.94e-01
REACTOME ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT 23 2.29e-01 1.45e-01 6.94e-01
REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM 23 2.29e-01 -1.45e-01 6.94e-01
REACTOME NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION 20 2.29e-01 1.55e-01 6.94e-01
REACTOME SIGNALING BY HEDGEHOG 148 2.29e-01 5.72e-02 6.94e-01
REACTOME FANCONI ANEMIA PATHWAY 35 2.30e-01 -1.17e-01 6.95e-01
REACTOME ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA 15 2.31e-01 1.79e-01 6.96e-01
REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE 277 2.33e-01 -4.17e-02 6.99e-01
REACTOME PROTEIN METHYLATION 17 2.33e-01 -1.67e-01 6.99e-01
REACTOME TERMINAL PATHWAY OF COMPLEMENT 8 2.34e-01 -2.43e-01 6.99e-01
REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 44 2.34e-01 1.04e-01 6.99e-01
REACTOME INITIATION OF NUCLEAR ENVELOPE NE REFORMATION 18 2.34e-01 -1.62e-01 6.99e-01
REACTOME ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS 41 2.36e-01 1.07e-01 7.03e-01
REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY 29 2.36e-01 1.27e-01 7.03e-01
REACTOME ALPHA DEFENSINS 6 2.38e-01 2.78e-01 7.05e-01
REACTOME PRE NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM 6 2.38e-01 2.78e-01 7.06e-01
REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION 32 2.39e-01 1.20e-01 7.06e-01
REACTOME CALCITONIN LIKE LIGAND RECEPTORS 10 2.39e-01 -2.15e-01 7.07e-01
REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS 5 2.40e-01 3.04e-01 7.07e-01
REACTOME TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY 30 2.41e-01 1.24e-01 7.07e-01
REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS 91 2.41e-01 -7.11e-02 7.07e-01
REACTOME FATTY ACIDS 15 2.42e-01 -1.74e-01 7.07e-01
REACTOME SIGNAL TRANSDUCTION BY L1 20 2.42e-01 1.51e-01 7.07e-01
REACTOME KILLING MECHANISMS 11 2.42e-01 2.04e-01 7.07e-01
REACTOME COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING 32 2.43e-01 -1.19e-01 7.09e-01
REACTOME CGMP EFFECTS 16 2.44e-01 -1.68e-01 7.09e-01
REACTOME ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS 20 2.44e-01 -1.51e-01 7.09e-01
REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV 1 INFECTION 5 2.45e-01 -3.00e-01 7.10e-01
REACTOME METABOLISM OF LIPIDS 709 2.45e-01 2.56e-02 7.10e-01
REACTOME NEDDYLATION 235 2.46e-01 -4.40e-02 7.10e-01
REACTOME RND2 GTPASE CYCLE 42 2.48e-01 1.03e-01 7.14e-01
REACTOME SIGNALING BY NTRK2 TRKB 25 2.48e-01 1.33e-01 7.14e-01
REACTOME CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND 16 2.50e-01 1.66e-01 7.15e-01
REACTOME PLATELET SENSITIZATION BY LDL 17 2.50e-01 1.61e-01 7.15e-01
REACTOME REGULATION OF IFNG SIGNALING 14 2.50e-01 1.77e-01 7.15e-01
REACTOME SUMO IS PROTEOLYTICALLY PROCESSED 6 2.50e-01 -2.71e-01 7.15e-01
REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS 6 2.50e-01 2.71e-01 7.15e-01
REACTOME FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS 8 2.51e-01 -2.34e-01 7.16e-01
REACTOME ENDOGENOUS STEROLS 26 2.53e-01 1.30e-01 7.16e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE 8 2.53e-01 2.33e-01 7.16e-01
REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION 10 2.53e-01 -2.09e-01 7.16e-01
REACTOME GLYCEROPHOSPHOLIPID CATABOLISM 7 2.53e-01 2.49e-01 7.16e-01
REACTOME VESICLE MEDIATED TRANSPORT 642 2.54e-01 2.64e-02 7.16e-01
REACTOME FC EPSILON RECEPTOR FCERI SIGNALING 127 2.56e-01 5.84e-02 7.16e-01
REACTOME FLT3 SIGNALING 38 2.57e-01 1.06e-01 7.16e-01
REACTOME ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS 5 2.57e-01 -2.93e-01 7.16e-01
REACTOME P38MAPK EVENTS 13 2.58e-01 1.81e-01 7.16e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER 28 2.58e-01 -1.23e-01 7.16e-01
REACTOME TRIGLYCERIDE BIOSYNTHESIS 12 2.59e-01 1.88e-01 7.16e-01
REACTOME EXTENSION OF TELOMERES 49 2.59e-01 -9.32e-02 7.16e-01
REACTOME DEGRADATION OF GLI1 BY THE PROTEASOME 59 2.59e-01 -8.49e-02 7.16e-01
REACTOME GLYCOSAMINOGLYCAN METABOLISM 118 2.59e-01 6.01e-02 7.16e-01
REACTOME DEFECTS IN BIOTIN BTN METABOLISM 8 2.60e-01 -2.30e-01 7.16e-01
REACTOME NEGATIVE REGULATION OF NOTCH4 SIGNALING 53 2.60e-01 -8.94e-02 7.16e-01
REACTOME PKA ACTIVATION IN GLUCAGON SIGNALLING 17 2.60e-01 1.58e-01 7.16e-01
REACTOME SUPPRESSION OF PHAGOSOMAL MATURATION 13 2.60e-01 -1.80e-01 7.16e-01
REACTOME CHROMATIN MODIFYING ENZYMES 252 2.60e-01 4.12e-02 7.16e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH CDK5 6 2.61e-01 2.65e-01 7.16e-01
REACTOME REGULATION OF PTEN STABILITY AND ACTIVITY 67 2.61e-01 -7.94e-02 7.16e-01
REACTOME SIGNALING BY WNT 318 2.61e-01 3.67e-02 7.16e-01
REACTOME ORGANIC CATION TRANSPORT 10 2.61e-01 2.05e-01 7.16e-01
REACTOME SIGNALING BY FGFR IN DISEASE 62 2.62e-01 8.24e-02 7.16e-01
REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX 13 2.62e-01 -1.80e-01 7.16e-01
REACTOME GAB1 SIGNALOSOME 17 2.62e-01 1.57e-01 7.16e-01
REACTOME PLATELET CALCIUM HOMEOSTASIS 27 2.65e-01 1.24e-01 7.18e-01
REACTOME N GLYCAN TRIMMING AND ELONGATION IN THE CIS GOLGI 5 2.65e-01 2.88e-01 7.18e-01
REACTOME OTHER SEMAPHORIN INTERACTIONS 18 2.65e-01 1.52e-01 7.18e-01
REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION 32 2.65e-01 1.14e-01 7.18e-01
REACTOME AUTOPHAGY 144 2.66e-01 5.37e-02 7.18e-01
REACTOME SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS 16 2.66e-01 1.61e-01 7.18e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL 15 2.66e-01 1.66e-01 7.18e-01
REACTOME GLUCONEOGENESIS 33 2.68e-01 -1.11e-01 7.19e-01
REACTOME G PROTEIN MEDIATED EVENTS 53 2.68e-01 8.79e-02 7.19e-01
REACTOME DUAL INCISION IN TC NER 63 2.68e-01 -8.07e-02 7.19e-01
REACTOME GLUCOCORTICOID BIOSYNTHESIS 10 2.69e-01 -2.02e-01 7.19e-01
REACTOME FBXW7 MUTANTS AND NOTCH1 IN CANCER 5 2.69e-01 2.86e-01 7.19e-01
REACTOME HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE 43 2.70e-01 -9.73e-02 7.20e-01
REACTOME INITIAL TRIGGERING OF COMPLEMENT 21 2.70e-01 -1.39e-01 7.20e-01
REACTOME LIPOPHAGY 9 2.72e-01 2.11e-01 7.20e-01
REACTOME GROWTH HORMONE RECEPTOR SIGNALING 24 2.72e-01 -1.29e-01 7.20e-01
REACTOME METAL ION SLC TRANSPORTERS 23 2.74e-01 1.32e-01 7.20e-01
REACTOME LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME 11 2.75e-01 1.90e-01 7.20e-01
REACTOME FORMATION OF INCISION COMPLEX IN GG NER 40 2.75e-01 -9.97e-02 7.20e-01
REACTOME MISMATCH REPAIR 15 2.76e-01 -1.63e-01 7.20e-01
REACTOME PHASE 4 RESTING MEMBRANE POTENTIAL 19 2.76e-01 1.44e-01 7.20e-01
REACTOME NCAM1 INTERACTIONS 41 2.77e-01 9.81e-02 7.20e-01
REACTOME ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION 28 2.78e-01 1.18e-01 7.20e-01
REACTOME METABOLISM OF COFACTORS 19 2.79e-01 -1.44e-01 7.20e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX2 117 2.80e-01 -5.79e-02 7.20e-01
REACTOME DEGRADATION OF DVL 56 2.80e-01 -8.35e-02 7.20e-01
REACTOME TRANSCRIPTIONAL REGULATION BY MECP2 60 2.80e-01 8.07e-02 7.20e-01
REACTOME SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER 54 2.80e-01 8.49e-02 7.20e-01
REACTOME PIWI INTERACTING RNA PIRNA BIOGENESIS 29 2.81e-01 1.16e-01 7.20e-01
REACTOME MODULATION BY MTB OF HOST IMMUNE SYSTEM 6 2.81e-01 -2.54e-01 7.20e-01
REACTOME RHOD GTPASE CYCLE 49 2.81e-01 8.90e-02 7.20e-01
REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER 81 2.81e-01 -6.93e-02 7.20e-01
REACTOME DEGRADATION OF AXIN 54 2.82e-01 -8.47e-02 7.20e-01
REACTOME GAP JUNCTION DEGRADATION 12 2.82e-01 1.79e-01 7.20e-01
REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION 13 2.82e-01 1.72e-01 7.20e-01
REACTOME GLUCURONIDATION 23 2.82e-01 -1.30e-01 7.20e-01
REACTOME RHOF GTPASE CYCLE 40 2.83e-01 9.82e-02 7.20e-01
REACTOME WNT MEDIATED ACTIVATION OF DVL 8 2.83e-01 2.19e-01 7.20e-01
REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION 60 2.83e-01 -8.01e-02 7.20e-01
REACTOME OPIOID SIGNALLING 89 2.84e-01 6.57e-02 7.20e-01
REACTOME CELL JUNCTION ORGANIZATION 89 2.85e-01 6.56e-02 7.20e-01
REACTOME RAF INDEPENDENT MAPK1 3 ACTIVATION 22 2.85e-01 1.32e-01 7.20e-01
REACTOME LATE ENDOSOMAL MICROAUTOPHAGY 33 2.85e-01 1.07e-01 7.20e-01
REACTOME FRS MEDIATED FGFR3 SIGNALING 19 2.86e-01 1.42e-01 7.20e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES 10 2.86e-01 -1.95e-01 7.20e-01
REACTOME HIV LIFE CYCLE 145 2.86e-01 -5.13e-02 7.20e-01
REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS 38 2.86e-01 -9.99e-02 7.20e-01
REACTOME REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS 7 2.86e-01 2.33e-01 7.20e-01
REACTOME NUCLEOTIDE BIOSYNTHESIS 14 2.86e-01 -1.65e-01 7.20e-01
REACTOME DEADENYLATION DEPENDENT MRNA DECAY 56 2.86e-01 -8.24e-02 7.20e-01
REACTOME PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING 5 2.88e-01 -2.74e-01 7.20e-01
REACTOME CELLULAR SENESCENCE 189 2.90e-01 -4.46e-02 7.20e-01
REACTOME ESTABLISHMENT OF SISTER CHROMATID COHESION 9 2.90e-01 -2.04e-01 7.20e-01
REACTOME RHO GTPASES ACTIVATE KTN1 11 2.90e-01 1.84e-01 7.20e-01
REACTOME FIBRONECTIN MATRIX FORMATION 6 2.90e-01 2.49e-01 7.20e-01
REACTOME REGULATION OF RUNX1 EXPRESSION AND ACTIVITY 17 2.90e-01 1.48e-01 7.20e-01
REACTOME DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING 61 2.90e-01 -7.83e-02 7.20e-01
REACTOME NRCAM INTERACTIONS 6 2.90e-01 -2.49e-01 7.20e-01
REACTOME PHASE 3 RAPID REPOLARISATION 8 2.90e-01 2.16e-01 7.20e-01
REACTOME LYSINE CATABOLISM 12 2.91e-01 -1.76e-01 7.20e-01
REACTOME ZINC TRANSPORTERS 15 2.91e-01 1.58e-01 7.20e-01
REACTOME NEUROFASCIN INTERACTIONS 6 2.91e-01 -2.49e-01 7.20e-01
REACTOME VEGFR2 MEDIATED CELL PROLIFERATION 19 2.91e-01 1.40e-01 7.20e-01
REACTOME MEMBRANE TRAFFICKING 603 2.92e-01 2.51e-02 7.21e-01
REACTOME BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA 5 2.93e-01 -2.72e-01 7.22e-01
REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE 35 2.95e-01 -1.02e-01 7.25e-01
REACTOME PLASMA LIPOPROTEIN REMODELING 33 2.95e-01 1.05e-01 7.25e-01
REACTOME BETA CATENIN INDEPENDENT WNT SIGNALING 145 2.96e-01 5.03e-02 7.26e-01
REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE 19 2.97e-01 -1.38e-01 7.26e-01
REACTOME SIGNALING BY KIT IN DISEASE 20 2.97e-01 1.35e-01 7.26e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING 6 2.98e-01 2.45e-01 7.27e-01
REACTOME REGULATED NECROSIS 57 2.99e-01 -7.96e-02 7.27e-01
REACTOME GRB7 EVENTS IN ERBB2 SIGNALING 5 3.00e-01 2.68e-01 7.27e-01
REACTOME REGULATION OF PTEN GENE TRANSCRIPTION 59 3.00e-01 7.81e-02 7.27e-01
REACTOME SEROTONIN RECEPTORS 11 3.00e-01 1.81e-01 7.27e-01
REACTOME COLLAGEN CHAIN TRIMERIZATION 42 3.01e-01 9.23e-02 7.27e-01
REACTOME NUCLEOTIDE EXCISION REPAIR 107 3.01e-01 -5.79e-02 7.27e-01
REACTOME CONJUGATION OF BENZOATE WITH GLYCINE 6 3.01e-01 -2.44e-01 7.27e-01
REACTOME UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION 19 3.02e-01 1.37e-01 7.27e-01
REACTOME SIGNALING BY NTRKS 132 3.02e-01 5.20e-02 7.27e-01
REACTOME NFE2L2 REGULATING ANTI OXIDANT DETOXIFICATION ENZYMES 17 3.04e-01 1.44e-01 7.27e-01
REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR 11 3.04e-01 1.79e-01 7.27e-01
REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE 20 3.04e-01 -1.33e-01 7.27e-01
REACTOME IKBA VARIANT LEADS TO EDA ID 6 3.05e-01 -2.42e-01 7.27e-01
REACTOME ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA 5 3.05e-01 2.65e-01 7.27e-01
REACTOME ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS 11 3.05e-01 -1.79e-01 7.27e-01
REACTOME LGI ADAM INTERACTIONS 14 3.06e-01 -1.58e-01 7.27e-01
REACTOME PROLACTIN RECEPTOR SIGNALING 15 3.06e-01 -1.53e-01 7.27e-01
REACTOME SIGNALLING TO ERKS 34 3.06e-01 1.01e-01 7.27e-01
REACTOME PYROPTOSIS 27 3.07e-01 -1.13e-01 7.29e-01
REACTOME FCGR ACTIVATION 11 3.08e-01 1.77e-01 7.31e-01
REACTOME INTESTINAL ABSORPTION 5 3.09e-01 2.63e-01 7.31e-01
REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS 16 3.09e-01 1.47e-01 7.31e-01
REACTOME DEFECTIVE RIPK1 MEDIATED REGULATED NECROSIS 7 3.11e-01 2.21e-01 7.33e-01
REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS 46 3.12e-01 8.62e-02 7.35e-01
REACTOME PREDNISONE ADME 10 3.13e-01 -1.84e-01 7.36e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE 20 3.14e-01 1.30e-01 7.36e-01
REACTOME ARMS MEDIATED ACTIVATION 7 3.14e-01 2.20e-01 7.36e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES 15 3.14e-01 1.50e-01 7.36e-01
REACTOME SCAVENGING BY CLASS B RECEPTORS 6 3.16e-01 2.36e-01 7.38e-01
REACTOME PHOSPHORYLATION OF THE APC C 20 3.16e-01 -1.29e-01 7.38e-01
REACTOME CHAPERONE MEDIATED AUTOPHAGY 20 3.17e-01 1.29e-01 7.38e-01
REACTOME SYNDECAN INTERACTIONS 26 3.17e-01 1.13e-01 7.38e-01
REACTOME RAF ACTIVATION 33 3.17e-01 1.01e-01 7.38e-01
REACTOME SODIUM PROTON EXCHANGERS 7 3.18e-01 2.18e-01 7.39e-01
REACTOME PEROXISOMAL PROTEIN IMPORT 62 3.20e-01 -7.31e-02 7.41e-01
REACTOME GLYCOGEN SYNTHESIS 13 3.20e-01 -1.59e-01 7.41e-01
REACTOME CHL1 INTERACTIONS 9 3.20e-01 -1.91e-01 7.41e-01
REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES 14 3.21e-01 1.53e-01 7.41e-01
REACTOME GP1B IX V ACTIVATION SIGNALLING 11 3.21e-01 1.73e-01 7.41e-01
REACTOME DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1 9 3.22e-01 -1.91e-01 7.41e-01
REACTOME RNA POLYMERASE II TRANSCRIPTION 1336 3.23e-01 -1.61e-02 7.42e-01
REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS 45 3.24e-01 -8.51e-02 7.42e-01
REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ 6 3.24e-01 2.32e-01 7.42e-01
REACTOME ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY 10 3.24e-01 1.80e-01 7.42e-01
REACTOME CA DEPENDENT EVENTS 36 3.25e-01 9.48e-02 7.42e-01
REACTOME MRNA CAPPING 28 3.25e-01 -1.07e-01 7.42e-01
REACTOME RAP1 SIGNALLING 16 3.25e-01 1.42e-01 7.42e-01
REACTOME EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION 27 3.26e-01 1.09e-01 7.42e-01
REACTOME TYROSINE CATABOLISM 5 3.27e-01 2.53e-01 7.43e-01
REACTOME SENSORY PERCEPTION OF TASTE 47 3.27e-01 8.26e-02 7.44e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES 16 3.28e-01 -1.41e-01 7.44e-01
REACTOME TRNA PROCESSING IN THE NUCLEUS 58 3.29e-01 -7.41e-02 7.45e-01
REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS 35 3.30e-01 -9.52e-02 7.45e-01
REACTOME RESPONSE OF MTB TO PHAGOCYTOSIS 22 3.30e-01 -1.20e-01 7.46e-01
REACTOME ASPARTATE AND ASPARAGINE METABOLISM 11 3.32e-01 -1.69e-01 7.47e-01
REACTOME MITOCHONDRIAL TRNA AMINOACYLATION 20 3.33e-01 -1.25e-01 7.47e-01
REACTOME SIGNALING BY FGFR3 39 3.33e-01 8.96e-02 7.47e-01
REACTOME HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS 9 3.33e-01 1.86e-01 7.47e-01
REACTOME RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR 19 3.34e-01 1.28e-01 7.48e-01
REACTOME TCR SIGNALING 113 3.35e-01 5.26e-02 7.49e-01
REACTOME CIPROFLOXACIN ADME 5 3.35e-01 -2.49e-01 7.49e-01
REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES 12 3.37e-01 -1.60e-01 7.50e-01
REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN 32 3.37e-01 -9.80e-02 7.50e-01
REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX 85 3.38e-01 6.02e-02 7.50e-01
REACTOME RHO GTPASES ACTIVATE PAKS 19 3.38e-01 1.27e-01 7.50e-01
REACTOME REGULATION BY C FLIP 11 3.38e-01 1.67e-01 7.50e-01
REACTOME TOXICITY OF BOTULINUM TOXIN TYPE D BOTD 5 3.38e-01 -2.47e-01 7.50e-01
REACTOME COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC 52 3.38e-01 7.67e-02 7.50e-01
REACTOME ATORVASTATIN ADME 9 3.40e-01 -1.84e-01 7.52e-01
REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE 11 3.40e-01 1.66e-01 7.52e-01
REACTOME SYNTHESIS OF PE 13 3.43e-01 1.52e-01 7.56e-01
REACTOME FGFR3 LIGAND BINDING AND ACTIVATION 12 3.43e-01 1.58e-01 7.56e-01
REACTOME HYALURONAN UPTAKE AND DEGRADATION 12 3.44e-01 1.58e-01 7.56e-01
REACTOME TELOMERE MAINTENANCE 106 3.45e-01 -5.31e-02 7.56e-01
REACTOME GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION 42 3.45e-01 8.42e-02 7.56e-01
REACTOME SYNAPTIC ADHESION LIKE MOLECULES 19 3.47e-01 1.25e-01 7.56e-01
REACTOME AMYLOID FIBER FORMATION 102 3.47e-01 -5.39e-02 7.56e-01
REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR 79 3.47e-01 -6.12e-02 7.56e-01
REACTOME ACTIVATION OF RAS IN B CELLS 5 3.47e-01 2.43e-01 7.56e-01
REACTOME 2 LTR CIRCLE FORMATION 7 3.47e-01 -2.05e-01 7.56e-01
REACTOME DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS 19 3.48e-01 -1.24e-01 7.56e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS 8 3.48e-01 -1.92e-01 7.56e-01
REACTOME MOLYBDENUM COFACTOR BIOSYNTHESIS 6 3.49e-01 2.21e-01 7.56e-01
REACTOME TNFR1 INDUCED PROAPOPTOTIC SIGNALING 23 3.50e-01 1.13e-01 7.56e-01
REACTOME SEMA3A PAK DEPENDENT AXON REPULSION 14 3.50e-01 1.44e-01 7.56e-01
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION 138 3.50e-01 -4.61e-02 7.56e-01
REACTOME HORMONE LIGAND BINDING RECEPTORS 12 3.50e-01 -1.56e-01 7.56e-01
REACTOME MICRORNA MIRNA BIOGENESIS 25 3.51e-01 1.08e-01 7.56e-01
REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX 8 3.53e-01 -1.90e-01 7.59e-01
REACTOME GPER1 SIGNALING 45 3.53e-01 8.01e-02 7.59e-01
REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS 33 3.54e-01 -9.33e-02 7.59e-01
REACTOME SIGNALING BY FGFR4 IN DISEASE 11 3.54e-01 1.61e-01 7.59e-01
REACTOME LIGAND RECEPTOR INTERACTIONS 8 3.54e-01 -1.89e-01 7.59e-01
REACTOME DISORDERS OF TRANSMEMBRANE TRANSPORTERS 170 3.55e-01 -4.12e-02 7.59e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR2 29 3.55e-01 9.92e-02 7.59e-01
REACTOME SIGNALING BY FGFR1 IN DISEASE 38 3.55e-01 8.66e-02 7.59e-01
REACTOME DEFECTIVE GALNT3 CAUSES HFTC 16 3.56e-01 -1.33e-01 7.59e-01
REACTOME DAP12 INTERACTIONS 37 3.56e-01 8.76e-02 7.59e-01
REACTOME GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION 7 3.57e-01 2.01e-01 7.59e-01
REACTOME ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE 9 3.57e-01 1.77e-01 7.59e-01
REACTOME FGFR2C LIGAND BINDING AND ACTIVATION 12 3.60e-01 1.53e-01 7.63e-01
REACTOME CILIUM ASSEMBLY 190 3.63e-01 -3.82e-02 7.70e-01
REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION 26 3.64e-01 -1.03e-01 7.70e-01
REACTOME GABA RECEPTOR ACTIVATION 57 3.64e-01 6.95e-02 7.70e-01
REACTOME VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS 42 3.65e-01 8.07e-02 7.70e-01
REACTOME REGULATION OF RAS BY GAPS 66 3.66e-01 -6.44e-02 7.70e-01
REACTOME EXTRA NUCLEAR ESTROGEN SIGNALING 74 3.66e-01 6.08e-02 7.70e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1 25 3.66e-01 1.04e-01 7.70e-01
REACTOME G2 M DNA REPLICATION CHECKPOINT 5 3.68e-01 -2.33e-01 7.71e-01
REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION 20 3.68e-01 -1.16e-01 7.71e-01
REACTOME SULFIDE OXIDATION TO SULFATE 6 3.68e-01 2.12e-01 7.71e-01
REACTOME ACYL CHAIN REMODELLING OF PI 17 3.70e-01 -1.26e-01 7.72e-01
REACTOME PEPTIDE HORMONE METABOLISM 84 3.71e-01 5.65e-02 7.72e-01
REACTOME SIGNALING BY TGFB FAMILY MEMBERS 119 3.71e-01 4.75e-02 7.72e-01
REACTOME LAMININ INTERACTIONS 28 3.71e-01 9.76e-02 7.72e-01
REACTOME PHOSPHORYLATION OF EMI1 6 3.72e-01 -2.11e-01 7.72e-01
REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS 16 3.72e-01 1.29e-01 7.72e-01
REACTOME THYROXINE BIOSYNTHESIS 10 3.73e-01 1.63e-01 7.72e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION 41 3.73e-01 -8.03e-02 7.72e-01
REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY 25 3.74e-01 1.03e-01 7.72e-01
REACTOME SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION 8 3.74e-01 1.82e-01 7.72e-01
REACTOME SHC MEDIATED CASCADE FGFR1 21 3.74e-01 1.12e-01 7.72e-01
REACTOME APOPTOTIC FACTOR MEDIATED RESPONSE 19 3.75e-01 -1.18e-01 7.72e-01
REACTOME VLDLR INTERNALISATION AND DEGRADATION 16 3.75e-01 -1.28e-01 7.72e-01
REACTOME RHO GTPASES ACTIVATE FORMINS 136 3.76e-01 -4.40e-02 7.72e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1 31 3.76e-01 9.19e-02 7.72e-01
REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE 17 3.76e-01 1.24e-01 7.72e-01
REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS 11 3.78e-01 1.53e-01 7.74e-01
REACTOME TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT 18 3.78e-01 -1.20e-01 7.74e-01
REACTOME CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS 19 3.78e-01 -1.17e-01 7.74e-01
REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS 62 3.82e-01 6.42e-02 7.76e-01
REACTOME CD209 DC SIGN SIGNALING 20 3.82e-01 1.13e-01 7.76e-01
REACTOME CALCINEURIN ACTIVATES NFAT 9 3.82e-01 -1.68e-01 7.76e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX3 94 3.82e-01 5.22e-02 7.76e-01
REACTOME HDR THROUGH HOMOLOGOUS RECOMBINATION HRR 66 3.82e-01 -6.22e-02 7.76e-01
REACTOME GLUCOSE METABOLISM 90 3.83e-01 -5.32e-02 7.78e-01
REACTOME HDL ASSEMBLY 8 3.84e-01 1.78e-01 7.78e-01
REACTOME TRNA AMINOACYLATION 40 3.84e-01 -7.95e-02 7.78e-01
REACTOME SARS COV 2 MODULATES AUTOPHAGY 11 3.85e-01 -1.51e-01 7.79e-01
REACTOME SENSING OF DNA DOUBLE STRAND BREAKS 6 3.86e-01 -2.04e-01 7.79e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K 12 3.87e-01 1.44e-01 7.81e-01
REACTOME PEXOPHAGY 11 3.89e-01 -1.50e-01 7.83e-01
REACTOME ATTACHMENT OF GPI ANCHOR TO UPAR 7 3.90e-01 -1.88e-01 7.84e-01
REACTOME SIGNALING BY EGFR IN CANCER 25 3.92e-01 -9.90e-02 7.86e-01
REACTOME SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX 15 3.92e-01 -1.28e-01 7.86e-01
REACTOME AQUAPORIN MEDIATED TRANSPORT 51 3.92e-01 6.92e-02 7.86e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL 14 3.93e-01 1.32e-01 7.86e-01
REACTOME OTHER INTERLEUKIN SIGNALING 24 3.94e-01 1.00e-01 7.87e-01
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM 688 3.96e-01 -1.90e-02 7.87e-01
REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET 8 3.96e-01 -1.73e-01 7.87e-01
REACTOME TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA 17 3.96e-01 -1.19e-01 7.87e-01
REACTOME LONG TERM POTENTIATION 22 3.96e-01 1.05e-01 7.87e-01
REACTOME CHYLOMICRON ASSEMBLY 10 3.96e-01 1.55e-01 7.87e-01
REACTOME EPH EPHRIN MEDIATED REPULSION OF CELLS 50 3.97e-01 6.92e-02 7.88e-01
REACTOME DEADENYLATION OF MRNA 25 3.99e-01 -9.74e-02 7.91e-01
REACTOME HIV ELONGATION ARREST AND RECOVERY 33 4.01e-01 8.44e-02 7.91e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION 45 4.02e-01 -7.22e-02 7.91e-01
REACTOME SIGNALING BY ALK IN CANCER 53 4.02e-01 -6.65e-02 7.91e-01
REACTOME SUMO IS TRANSFERRED FROM E1 TO E2 UBE2I UBC9 7 4.03e-01 1.83e-01 7.91e-01
REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION 36 4.03e-01 -8.06e-02 7.91e-01
REACTOME DAG AND IP3 SIGNALING 40 4.03e-01 7.64e-02 7.91e-01
REACTOME EPH EPHRIN SIGNALING 90 4.03e-01 5.10e-02 7.91e-01
REACTOME ACTIVATION OF MATRIX METALLOPROTEINASES 30 4.04e-01 8.81e-02 7.91e-01
REACTOME RUNX2 REGULATES CHONDROCYTE MATURATION 5 4.04e-01 2.16e-01 7.91e-01
REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE 30 4.05e-01 8.78e-02 7.91e-01
REACTOME IRAK4 DEFICIENCY TLR2 4 17 4.05e-01 -1.17e-01 7.91e-01
REACTOME SIGNALING BY FGFR1 49 4.05e-01 6.87e-02 7.91e-01
REACTOME CITRIC ACID CYCLE TCA CYCLE 21 4.07e-01 -1.05e-01 7.91e-01
REACTOME SIGNALING BY NOTCH 234 4.07e-01 3.15e-02 7.91e-01
REACTOME JOSEPHIN DOMAIN DUBS 11 4.08e-01 -1.44e-01 7.91e-01
REACTOME PROCESSING OF INTRONLESS PRE MRNAS 19 4.10e-01 -1.09e-01 7.91e-01
REACTOME FORMATION OF PARAXIAL MESODERM 22 4.10e-01 1.01e-01 7.91e-01
REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES 21 4.10e-01 1.04e-01 7.91e-01
REACTOME HIV TRANSCRIPTION INITIATION 43 4.11e-01 -7.24e-02 7.91e-01
REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 122 4.11e-01 4.31e-02 7.91e-01
REACTOME DISEASES OF MISMATCH REPAIR MMR 5 4.12e-01 -2.12e-01 7.91e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1 20 4.13e-01 -1.06e-01 7.91e-01
REACTOME RET SIGNALING 40 4.13e-01 7.48e-02 7.91e-01
REACTOME SIGNALING BY FGFR2 72 4.13e-01 5.58e-02 7.91e-01
REACTOME CARNITINE METABOLISM 13 4.14e-01 1.31e-01 7.91e-01
REACTOME TRAF6 MEDIATED NF KB ACTIVATION 24 4.14e-01 -9.63e-02 7.91e-01
REACTOME CROSSLINKING OF COLLAGEN FIBRILS 16 4.15e-01 1.18e-01 7.91e-01
REACTOME PI5P REGULATES TP53 ACETYLATION 9 4.16e-01 1.57e-01 7.91e-01
REACTOME SODIUM COUPLED PHOSPHATE COTRANSPORTERS 5 4.16e-01 -2.10e-01 7.91e-01
REACTOME CELLULAR RESPONSE TO HEAT STRESS 99 4.16e-01 -4.73e-02 7.91e-01
REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR 19 4.16e-01 1.08e-01 7.91e-01
REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS 14 4.16e-01 1.25e-01 7.91e-01
REACTOME DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B 7 4.17e-01 1.77e-01 7.91e-01
REACTOME ANTIMICROBIAL PEPTIDES 76 4.17e-01 5.39e-02 7.91e-01
REACTOME CHONDROITIN SULFATE BIOSYNTHESIS 18 4.17e-01 1.11e-01 7.91e-01
REACTOME NECTIN NECL TRANS HETERODIMERIZATION 7 4.17e-01 1.77e-01 7.91e-01
REACTOME DOPAMINE RECEPTORS 5 4.17e-01 2.10e-01 7.91e-01
REACTOME CLATHRIN MEDIATED ENDOCYTOSIS 139 4.17e-01 3.98e-02 7.91e-01
REACTOME ACTIVATION OF AMPK DOWNSTREAM OF NMDARS 28 4.18e-01 8.84e-02 7.92e-01
REACTOME BICARBONATE TRANSPORTERS 10 4.20e-01 1.47e-01 7.95e-01
REACTOME NEF MEDIATED CD8 DOWN REGULATION 7 4.22e-01 1.75e-01 7.96e-01
REACTOME REGULATION OF PTEN LOCALIZATION 8 4.23e-01 -1.64e-01 7.96e-01
REACTOME SIALIC ACID METABOLISM 33 4.23e-01 8.07e-02 7.96e-01
REACTOME SIGNALING BY FGFR 85 4.23e-01 5.03e-02 7.96e-01
REACTOME REGULATION OF IFNA IFNB SIGNALING 23 4.24e-01 -9.63e-02 7.98e-01
REACTOME SIGNALING BY NOTCH3 48 4.25e-01 6.66e-02 7.98e-01
REACTOME INTRINSIC PATHWAY FOR APOPTOSIS 54 4.27e-01 6.25e-02 8.01e-01
REACTOME MULTIFUNCTIONAL ANION EXCHANGERS 9 4.28e-01 -1.53e-01 8.02e-01
REACTOME TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS 55 4.28e-01 6.17e-02 8.02e-01
REACTOME TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA 36 4.31e-01 -7.59e-02 8.03e-01
REACTOME SIGNALING BY ERBB4 57 4.31e-01 -6.03e-02 8.03e-01
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION 81 4.31e-01 -5.06e-02 8.03e-01
REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES 22 4.32e-01 -9.69e-02 8.03e-01
REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 98 4.32e-01 -4.59e-02 8.03e-01
REACTOME METABOLISM OF VITAMINS AND COFACTORS 185 4.33e-01 3.34e-02 8.03e-01
REACTOME METABOLISM OF FAT SOLUBLE VITAMINS 46 4.34e-01 6.66e-02 8.03e-01
REACTOME MITOCHONDRIAL BIOGENESIS 87 4.35e-01 -4.84e-02 8.03e-01
REACTOME DEFECTIVE F9 ACTIVATION 5 4.35e-01 2.02e-01 8.03e-01
REACTOME NUCLEAR EVENTS MEDIATED BY NFE2L2 77 4.36e-01 -5.14e-02 8.03e-01
REACTOME MIRO GTPASE CYCLE 8 4.36e-01 1.59e-01 8.03e-01
REACTOME UPTAKE AND FUNCTION OF ANTHRAX TOXINS 11 4.37e-01 1.35e-01 8.03e-01
REACTOME DUAL INCISION IN GG NER 39 4.37e-01 -7.20e-02 8.03e-01
REACTOME DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS 14 4.37e-01 1.20e-01 8.03e-01
REACTOME RND3 GTPASE CYCLE 41 4.38e-01 7.01e-02 8.03e-01
REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB 19 4.38e-01 1.03e-01 8.03e-01
REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL 12 4.38e-01 -1.29e-01 8.03e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH PI3K 6 4.38e-01 1.83e-01 8.03e-01
REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE 10 4.39e-01 1.41e-01 8.03e-01
REACTOME DISSOLUTION OF FIBRIN CLOT 13 4.39e-01 1.24e-01 8.03e-01
REACTOME SIGNALING BY ERBB2 ECD MUTANTS 16 4.41e-01 -1.11e-01 8.06e-01
REACTOME IRF3 MEDIATED INDUCTION OF TYPE I IFN 13 4.41e-01 -1.23e-01 8.06e-01
REACTOME CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY 25 4.42e-01 8.88e-02 8.07e-01
REACTOME MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS 17 4.44e-01 1.07e-01 8.08e-01
REACTOME SEMA4D IN SEMAPHORIN SIGNALING 24 4.44e-01 9.02e-02 8.08e-01
REACTOME MRNA EDITING C TO U CONVERSION 8 4.44e-01 -1.56e-01 8.08e-01
REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN 15 4.46e-01 1.14e-01 8.09e-01
REACTOME NUCLEAR IMPORT OF REV PROTEIN 34 4.46e-01 -7.55e-02 8.09e-01
REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS 18 4.47e-01 1.04e-01 8.09e-01
REACTOME METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS 122 4.48e-01 3.98e-02 8.10e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR3 24 4.48e-01 8.95e-02 8.10e-01
REACTOME MET PROMOTES CELL MOTILITY 41 4.50e-01 6.82e-02 8.11e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE 74 4.51e-01 5.07e-02 8.11e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS 14 4.51e-01 1.16e-01 8.11e-01
REACTOME MAPK3 ERK1 ACTIVATION 10 4.51e-01 1.38e-01 8.11e-01
REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK 17 4.52e-01 1.05e-01 8.11e-01
REACTOME ACTIVATION OF CASPASES THROUGH APOPTOSOME MEDIATED CLEAVAGE 5 4.52e-01 -1.94e-01 8.11e-01
REACTOME HDR THROUGH MMEJ ALT NHEJ 12 4.52e-01 -1.25e-01 8.11e-01
REACTOME DISEASES OF BASE EXCISION REPAIR 5 4.54e-01 1.93e-01 8.14e-01
REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION 19 4.56e-01 -9.89e-02 8.15e-01
REACTOME SENSORY PERCEPTION OF SALTY TASTE 6 4.56e-01 1.76e-01 8.15e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY DVL INTERACTING PROTEINS 5 4.57e-01 1.92e-01 8.16e-01
REACTOME BIOSYNTHESIS OF MARESINS 8 4.58e-01 1.52e-01 8.17e-01
REACTOME REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA 15 4.58e-01 -1.11e-01 8.17e-01
REACTOME COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM 21 4.59e-01 9.34e-02 8.17e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN 13 4.60e-01 1.18e-01 8.17e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY 19 4.63e-01 9.72e-02 8.20e-01
REACTOME BETA OXIDATION OF BUTANOYL COA TO ACETYL COA 5 4.63e-01 -1.89e-01 8.20e-01
REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION 6 4.63e-01 1.73e-01 8.20e-01
REACTOME NEUTROPHIL DEGRANULATION 460 4.64e-01 -1.99e-02 8.20e-01
REACTOME RUNX3 REGULATES P14 ARF 10 4.65e-01 1.33e-01 8.20e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX 91 4.65e-01 4.43e-02 8.20e-01
REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION 31 4.65e-01 7.58e-02 8.20e-01
REACTOME SERINE BIOSYNTHESIS 9 4.67e-01 -1.40e-01 8.20e-01
REACTOME MET INTERACTS WITH TNS PROTEINS 5 4.67e-01 1.88e-01 8.20e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1 229 4.67e-01 2.79e-02 8.20e-01
REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS 66 4.68e-01 5.17e-02 8.20e-01
REACTOME ASSEMBLY OF THE HIV VIRION 16 4.69e-01 -1.05e-01 8.20e-01
REACTOME ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING 9 4.69e-01 -1.39e-01 8.20e-01
REACTOME SIGNALING BY NOTCH2 32 4.70e-01 7.38e-02 8.20e-01
REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF 53 4.71e-01 5.73e-02 8.20e-01
REACTOME INTERFERON GAMMA SIGNALING 88 4.71e-01 -4.44e-02 8.20e-01
REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION 20 4.72e-01 -9.30e-02 8.20e-01
REACTOME G2 PHASE 5 4.72e-01 -1.86e-01 8.20e-01
REACTOME TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS 26 4.72e-01 8.14e-02 8.20e-01
REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS 9 4.74e-01 -1.38e-01 8.20e-01
REACTOME REGULATION OF SIGNALING BY CBL 22 4.74e-01 8.82e-02 8.20e-01
REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS 23 4.74e-01 8.63e-02 8.20e-01
REACTOME INTERLEUKIN 35 SIGNALLING 12 4.74e-01 1.19e-01 8.20e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2 13 4.74e-01 1.15e-01 8.20e-01
REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS 188 4.74e-01 -3.03e-02 8.20e-01
REACTOME LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX 5 4.74e-01 1.85e-01 8.20e-01
REACTOME MET ACTIVATES PTK2 SIGNALING 30 4.74e-01 7.55e-02 8.20e-01
REACTOME INTERLEUKIN 20 FAMILY SIGNALING 25 4.75e-01 8.26e-02 8.20e-01
REACTOME SYNTHESIS OF PG 8 4.76e-01 1.45e-01 8.21e-01
REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS 63 4.77e-01 -5.18e-02 8.21e-01
REACTOME RETROGRADE NEUROTROPHIN SIGNALLING 14 4.77e-01 1.10e-01 8.21e-01
REACTOME SIGNALING BY NOTCH4 80 4.78e-01 -4.59e-02 8.21e-01
REACTOME DNA DOUBLE STRAND BREAK REPAIR 162 4.78e-01 -3.23e-02 8.21e-01
REACTOME SPRY REGULATION OF FGF SIGNALING 16 4.78e-01 1.02e-01 8.21e-01
REACTOME COENZYME A BIOSYNTHESIS 8 4.79e-01 -1.45e-01 8.21e-01
REACTOME PRC2 METHYLATES HISTONES AND DNA 65 4.80e-01 -5.07e-02 8.21e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH PI3K 7 4.80e-01 1.54e-01 8.21e-01
REACTOME DEVELOPMENTAL BIOLOGY 1115 4.81e-01 -1.25e-02 8.21e-01
REACTOME BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS 10 4.82e-01 1.28e-01 8.22e-01
REACTOME DOWNREGULATION OF ERBB2 SIGNALING 29 4.82e-01 -7.54e-02 8.22e-01
REACTOME UNWINDING OF DNA 12 4.84e-01 -1.17e-01 8.22e-01
REACTOME DNA METHYLATION 58 4.84e-01 -5.31e-02 8.22e-01
REACTOME APOPTOTIC EXECUTION PHASE 49 4.84e-01 5.77e-02 8.22e-01
REACTOME NGF STIMULATED TRANSCRIPTION 38 4.84e-01 -6.55e-02 8.22e-01
REACTOME TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION 5 4.85e-01 -1.80e-01 8.22e-01
REACTOME CREATINE METABOLISM 9 4.86e-01 -1.34e-01 8.22e-01
REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION 8 4.86e-01 -1.42e-01 8.22e-01
REACTOME SYNTHESIS OF UDP N ACETYL GLUCOSAMINE 7 4.87e-01 -1.52e-01 8.22e-01
REACTOME TRYPTOPHAN CATABOLISM 14 4.87e-01 -1.07e-01 8.22e-01
REACTOME MINERALOCORTICOID BIOSYNTHESIS 6 4.88e-01 1.64e-01 8.22e-01
REACTOME FLT3 SIGNALING BY CBL MUTANTS 7 4.88e-01 -1.51e-01 8.22e-01
REACTOME OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS 8 4.90e-01 1.41e-01 8.22e-01
REACTOME GOLGI TO ER RETROGRADE TRANSPORT 132 4.91e-01 -3.47e-02 8.22e-01
REACTOME CALNEXIN CALRETICULIN CYCLE 26 4.91e-01 -7.81e-02 8.22e-01
REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL 41 4.91e-01 -6.21e-02 8.22e-01
REACTOME SUMOYLATION OF DNA METHYLATION PROTEINS 16 4.91e-01 -9.94e-02 8.22e-01
REACTOME ATTENUATION PHASE 27 4.92e-01 -7.64e-02 8.22e-01
REACTOME DNA STRAND ELONGATION 31 4.92e-01 -7.13e-02 8.22e-01
REACTOME HDR THROUGH SINGLE STRAND ANNEALING SSA 37 4.93e-01 -6.52e-02 8.22e-01
REACTOME SIGNALING BY NOTCH1 T 7 9 NOTCH1 M1580 K2555 TRANSLOCATION MUTANT 7 4.93e-01 1.50e-01 8.22e-01
REACTOME NUCLEAR ENVELOPE NE REASSEMBLY 74 4.93e-01 -4.61e-02 8.22e-01
REACTOME BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA 17 4.94e-01 -9.58e-02 8.22e-01
REACTOME VITAMIN B5 PANTOTHENATE METABOLISM 16 4.94e-01 -9.86e-02 8.22e-01
REACTOME ARYL HYDROCARBON RECEPTOR SIGNALLING 6 4.95e-01 1.61e-01 8.22e-01
REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC 198 4.95e-01 -2.81e-02 8.22e-01
REACTOME BASE EXCISION REPAIR AP SITE FORMATION 59 4.96e-01 -5.12e-02 8.23e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS 12 4.96e-01 1.13e-01 8.23e-01
REACTOME NUCLEAR PORE COMPLEX NPC DISASSEMBLY 36 4.97e-01 -6.55e-02 8.23e-01
REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN 76 4.98e-01 4.50e-02 8.23e-01
REACTOME TYSND1 CLEAVES PEROXISOMAL PROTEINS 7 4.98e-01 1.48e-01 8.23e-01
REACTOME POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION 27 4.99e-01 -7.51e-02 8.25e-01
REACTOME NEGATIVE REGULATION OF MET ACTIVITY 20 5.01e-01 8.70e-02 8.25e-01
REACTOME CHREBP ACTIVATES METABOLIC GENE EXPRESSION 8 5.01e-01 -1.37e-01 8.25e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG 7 5.02e-01 1.47e-01 8.25e-01
REACTOME REDUCTION OF CYTOSOLIC CA LEVELS 11 5.03e-01 1.17e-01 8.25e-01
REACTOME ADHERENS JUNCTIONS INTERACTIONS 33 5.03e-01 -6.74e-02 8.25e-01
REACTOME DNA DAMAGE RECOGNITION IN GG NER 36 5.03e-01 -6.45e-02 8.25e-01
REACTOME UPTAKE AND ACTIONS OF BACTERIAL TOXINS 28 5.04e-01 7.30e-02 8.25e-01
REACTOME INTERLEUKIN 1 SIGNALING 110 5.04e-01 -3.69e-02 8.25e-01
REACTOME TELOMERE C STRAND LAGGING STRAND SYNTHESIS 33 5.04e-01 -6.71e-02 8.25e-01
REACTOME GLYCOLYSIS 70 5.05e-01 -4.60e-02 8.25e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES 8 5.06e-01 1.36e-01 8.25e-01
REACTOME SIGNALING BY CSF1 M CSF IN MYELOID CELLS 30 5.06e-01 7.01e-02 8.25e-01
REACTOME EGFR DOWNREGULATION 30 5.07e-01 7.01e-02 8.25e-01
REACTOME SIGNALING BY NTRK3 TRKC 17 5.07e-01 9.30e-02 8.25e-01
REACTOME UCH PROTEINASES 99 5.07e-01 -3.86e-02 8.25e-01
REACTOME HCMV EARLY EVENTS 128 5.08e-01 -3.39e-02 8.25e-01
REACTOME METABOLISM OF STEROIDS 150 5.09e-01 -3.13e-02 8.25e-01
REACTOME TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE 10 5.09e-01 1.21e-01 8.25e-01
REACTOME SHC MEDIATED CASCADE FGFR3 17 5.09e-01 9.25e-02 8.25e-01
REACTOME MRNA EDITING 10 5.11e-01 -1.20e-01 8.26e-01
REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY 51 5.11e-01 -5.32e-02 8.26e-01
REACTOME COLLAGEN DEGRADATION 61 5.13e-01 4.84e-02 8.29e-01
REACTOME BETA OXIDATION OF PRISTANOYL COA 9 5.14e-01 -1.26e-01 8.29e-01
REACTOME DOWNREGULATION OF ERBB4 SIGNALING 9 5.15e-01 -1.25e-01 8.30e-01
REACTOME ORGANIC ANION TRANSPORT 5 5.15e-01 1.68e-01 8.30e-01
REACTOME HYALURONAN BIOSYNTHESIS AND EXPORT 5 5.16e-01 -1.68e-01 8.30e-01
REACTOME STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS 10 5.16e-01 -1.19e-01 8.30e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12 22 5.16e-01 7.99e-02 8.30e-01
REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB 5 5.18e-01 1.67e-01 8.30e-01
REACTOME ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING 23 5.18e-01 7.79e-02 8.30e-01
REACTOME MITOCHONDRIAL UNCOUPLING 5 5.18e-01 1.67e-01 8.30e-01
REACTOME DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A 5 5.19e-01 1.67e-01 8.30e-01
REACTOME SHC1 EVENTS IN EGFR SIGNALING 14 5.20e-01 -9.94e-02 8.31e-01
REACTOME CYTOSOLIC TRNA AMINOACYLATION 22 5.22e-01 -7.89e-02 8.33e-01
REACTOME DEUBIQUITINATION 260 5.22e-01 -2.31e-02 8.33e-01
REACTOME OXIDATIVE STRESS INDUCED SENESCENCE 118 5.23e-01 -3.40e-02 8.34e-01
REACTOME TRANSPORT OF NUCLEOTIDE SUGARS 8 5.24e-01 -1.30e-01 8.35e-01
REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX 31 5.25e-01 -6.60e-02 8.35e-01
REACTOME SIGNALING BY WNT IN CANCER 32 5.28e-01 6.45e-02 8.38e-01
REACTOME FGFR2 ALTERNATIVE SPLICING 27 5.28e-01 -7.02e-02 8.38e-01
REACTOME NICOTINAMIDE SALVAGING 19 5.28e-01 8.36e-02 8.38e-01
REACTOME DEGRADATION OF CYSTEINE AND HOMOCYSTEINE 15 5.30e-01 -9.38e-02 8.39e-01
REACTOME ARACHIDONIC ACID METABOLISM 57 5.31e-01 -4.80e-02 8.41e-01
REACTOME PLASMA LIPOPROTEIN CLEARANCE 37 5.31e-01 5.95e-02 8.41e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS 15 5.32e-01 -9.32e-02 8.41e-01
REACTOME DIGESTION 17 5.33e-01 -8.73e-02 8.42e-01
REACTOME METALLOPROTEASE DUBS 36 5.34e-01 -6.00e-02 8.42e-01
REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION 90 5.34e-01 3.79e-02 8.42e-01
REACTOME RUNX3 REGULATES NOTCH SIGNALING 13 5.35e-01 9.93e-02 8.42e-01
REACTOME SPERM MOTILITY AND TAXES 9 5.36e-01 1.19e-01 8.42e-01
REACTOME SIGNALING BY HIPPO 19 5.36e-01 -8.20e-02 8.42e-01
REACTOME SIGNAL AMPLIFICATION 33 5.37e-01 6.20e-02 8.42e-01
REACTOME KERATAN SULFATE BIOSYNTHESIS 28 5.38e-01 6.73e-02 8.42e-01
REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY 10 5.38e-01 1.12e-01 8.42e-01
REACTOME GLUTAMATE AND GLUTAMINE METABOLISM 13 5.38e-01 -9.85e-02 8.42e-01
REACTOME MYD88 INDEPENDENT TLR4 CASCADE 103 5.39e-01 -3.51e-02 8.42e-01
REACTOME LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS 19 5.39e-01 8.15e-02 8.42e-01
REACTOME SENSORY PERCEPTION 555 5.40e-01 -1.52e-02 8.42e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3 11 5.40e-01 1.07e-01 8.42e-01
REACTOME INTERLEUKIN 1 PROCESSING 9 5.40e-01 -1.18e-01 8.42e-01
REACTOME SARS COV 2 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS 12 5.41e-01 1.02e-01 8.42e-01
REACTOME TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX 10 5.43e-01 -1.11e-01 8.44e-01
REACTOME CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2 11 5.44e-01 -1.06e-01 8.45e-01
REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES 34 5.46e-01 -5.98e-02 8.47e-01
REACTOME PP2A MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS 6 5.46e-01 -1.42e-01 8.47e-01
REACTOME ACTIVATION OF C3 AND C5 6 5.49e-01 1.41e-01 8.51e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION 89 5.51e-01 -3.66e-02 8.53e-01
REACTOME CAMK IV MEDIATED PHOSPHORYLATION OF CREB 10 5.52e-01 1.09e-01 8.53e-01
REACTOME SYNTHESIS OF DIPHTHAMIDE EEF2 8 5.53e-01 -1.21e-01 8.53e-01
REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION 23 5.53e-01 -7.15e-02 8.53e-01
REACTOME DERMATAN SULFATE BIOSYNTHESIS 10 5.53e-01 -1.08e-01 8.53e-01
REACTOME METHYLATION 14 5.55e-01 9.11e-02 8.53e-01
REACTOME FGFR1B LIGAND BINDING AND ACTIVATION 6 5.55e-01 1.39e-01 8.53e-01
REACTOME METHIONINE SALVAGE PATHWAY 6 5.56e-01 -1.39e-01 8.53e-01
REACTOME INTERLEUKIN 6 SIGNALING 11 5.56e-01 1.03e-01 8.53e-01
REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER 18 5.56e-01 -8.01e-02 8.53e-01
REACTOME SUMOYLATION 179 5.56e-01 2.55e-02 8.53e-01
REACTOME DCC MEDIATED ATTRACTIVE SIGNALING 14 5.57e-01 9.07e-02 8.53e-01
REACTOME KINESINS 59 5.57e-01 -4.42e-02 8.53e-01
REACTOME COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING 38 5.61e-01 -5.46e-02 8.57e-01
REACTOME ACYL CHAIN REMODELLING OF PS 22 5.62e-01 -7.15e-02 8.57e-01
REACTOME FOXO MEDIATED TRANSCRIPTION 65 5.62e-01 -4.16e-02 8.57e-01
REACTOME KERATAN SULFATE KERATIN METABOLISM 34 5.64e-01 5.72e-02 8.57e-01
REACTOME DISEASES OF IMMUNE SYSTEM 29 5.64e-01 -6.19e-02 8.57e-01
REACTOME HEDGEHOG LIGAND BIOGENESIS 64 5.64e-01 -4.17e-02 8.57e-01
REACTOME TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS 29 5.64e-01 6.18e-02 8.57e-01
REACTOME DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15 8 5.64e-01 1.18e-01 8.57e-01
REACTOME ERBB2 ACTIVATES PTK6 SIGNALING 13 5.66e-01 -9.20e-02 8.59e-01
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION 1356 5.68e-01 -9.23e-03 8.61e-01
REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES 7 5.69e-01 -1.24e-01 8.61e-01
REACTOME CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE 49 5.69e-01 4.70e-02 8.61e-01
REACTOME DIGESTION OF DIETARY LIPID 7 5.70e-01 -1.24e-01 8.61e-01
REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS 43 5.70e-01 5.00e-02 8.61e-01
REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND 14 5.71e-01 -8.75e-02 8.61e-01
REACTOME BUDDING AND MATURATION OF HIV VIRION 28 5.72e-01 -6.18e-02 8.62e-01
REACTOME HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS 7 5.74e-01 1.23e-01 8.63e-01
REACTOME PEPTIDE LIGAND BINDING RECEPTORS 188 5.74e-01 2.38e-02 8.63e-01
REACTOME METABOLISM OF FOLATE AND PTERINES 17 5.75e-01 7.86e-02 8.63e-01
REACTOME SIGNALING BY ERBB2 IN CANCER 26 5.76e-01 -6.33e-02 8.63e-01
REACTOME GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION 34 5.77e-01 5.52e-02 8.63e-01
REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON 17 5.77e-01 -7.80e-02 8.63e-01
REACTOME NUCLEAR ENVELOPE BREAKDOWN 52 5.77e-01 -4.47e-02 8.63e-01
REACTOME INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS 37 5.78e-01 -5.28e-02 8.63e-01
REACTOME NOSTRIN MEDIATED ENOS TRAFFICKING 5 5.79e-01 -1.43e-01 8.63e-01
REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS 32 5.80e-01 5.66e-02 8.63e-01
REACTOME HEDGEHOG ON STATE 85 5.80e-01 -3.47e-02 8.63e-01
REACTOME SIGNALLING TO RAS 20 5.80e-01 7.15e-02 8.63e-01
REACTOME INTERLEUKIN 37 SIGNALING 20 5.80e-01 7.14e-02 8.63e-01
REACTOME VEGF LIGAND RECEPTOR INTERACTIONS 7 5.81e-01 -1.21e-01 8.63e-01
REACTOME SUMO IS CONJUGATED TO E1 UBA2 SAE1 5 5.81e-01 1.43e-01 8.63e-01
REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM 78 5.82e-01 -3.61e-02 8.63e-01
REACTOME SIGNALING BY NUCLEAR RECEPTORS 283 5.83e-01 1.90e-02 8.63e-01
REACTOME IRE1ALPHA ACTIVATES CHAPERONES 48 5.83e-01 4.58e-02 8.63e-01
REACTOME RESPONSE TO METAL IONS 14 5.84e-01 -8.46e-02 8.63e-01
REACTOME NUCLEOTIDE CATABOLISM 35 5.84e-01 -5.35e-02 8.63e-01
REACTOME PHENYLALANINE AND TYROSINE METABOLISM 11 5.85e-01 9.51e-02 8.63e-01
REACTOME DISEASES OF PROGRAMMED CELL DEATH 96 5.85e-01 -3.23e-02 8.63e-01
REACTOME PRE NOTCH EXPRESSION AND PROCESSING 112 5.85e-01 2.99e-02 8.63e-01
REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM 45 5.86e-01 4.69e-02 8.63e-01
REACTOME CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN 45 5.86e-01 -4.69e-02 8.63e-01
REACTOME HDMS DEMETHYLATE HISTONES 40 5.87e-01 4.97e-02 8.63e-01
REACTOME PROTEIN REPAIR 6 5.87e-01 1.28e-01 8.63e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES 61 5.88e-01 -4.01e-02 8.63e-01
REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP 41 5.88e-01 4.89e-02 8.63e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE 11 5.88e-01 9.44e-02 8.63e-01
REACTOME SULFUR AMINO ACID METABOLISM 27 5.90e-01 -5.98e-02 8.64e-01
REACTOME ALK MUTANTS BIND TKIS 12 5.91e-01 -8.97e-02 8.64e-01
REACTOME INDUCTION OF CELL CELL FUSION 12 5.91e-01 -8.97e-02 8.64e-01
REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE 24 5.91e-01 6.34e-02 8.64e-01
REACTOME NEUREXINS AND NEUROLIGINS 51 5.91e-01 -4.35e-02 8.64e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING 11 5.94e-01 -9.28e-02 8.66e-01
REACTOME FORMATION OF XYLULOSE 5 PHOSPHATE 5 5.94e-01 -1.37e-01 8.66e-01
REACTOME G PROTEIN ACTIVATION 24 5.95e-01 6.27e-02 8.66e-01
REACTOME VITAMIN D CALCIFEROL METABOLISM 12 5.96e-01 8.84e-02 8.67e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH CDC42 19 5.96e-01 7.02e-02 8.67e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS 5 5.96e-01 1.37e-01 8.67e-01
REACTOME CIRCADIAN CLOCK 68 5.97e-01 3.71e-02 8.67e-01
REACTOME CD163 MEDIATING AN ANTI INFLAMMATORY RESPONSE 9 5.99e-01 1.01e-01 8.67e-01
REACTOME VASOPRESSIN LIKE RECEPTORS 5 5.99e-01 1.36e-01 8.67e-01
REACTOME VLDL ASSEMBLY 5 6.00e-01 1.35e-01 8.67e-01
REACTOME FATTY ACID METABOLISM 170 6.01e-01 -2.33e-02 8.67e-01
REACTOME EPHB MEDIATED FORWARD SIGNALING 41 6.01e-01 4.72e-02 8.67e-01
REACTOME ACTIVATION OF PPARGC1A PGC 1ALPHA BY PHOSPHORYLATION 10 6.02e-01 9.53e-02 8.67e-01
REACTOME INTERLEUKIN 17 SIGNALING 66 6.03e-01 -3.70e-02 8.67e-01
REACTOME REGULATION OF RUNX3 EXPRESSION AND ACTIVITY 54 6.03e-01 -4.09e-02 8.67e-01
REACTOME PROPIONYL COA CATABOLISM 5 6.03e-01 -1.34e-01 8.67e-01
REACTOME TIE2 SIGNALING 18 6.04e-01 7.06e-02 8.67e-01
REACTOME PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS 21 6.04e-01 6.54e-02 8.67e-01
REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT 222 6.05e-01 2.02e-02 8.67e-01
REACTOME REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR 11 6.05e-01 -9.00e-02 8.67e-01
REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY 14 6.06e-01 7.96e-02 8.67e-01
REACTOME ROLE OF ABL IN ROBO SLIT SIGNALING 8 6.06e-01 -1.05e-01 8.67e-01
REACTOME PHASE 1 INACTIVATION OF FAST NA CHANNELS 6 6.06e-01 -1.22e-01 8.67e-01
REACTOME CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS 100 6.07e-01 2.97e-02 8.68e-01
REACTOME SMAC XIAP REGULATED APOPTOTIC RESPONSE 7 6.07e-01 -1.12e-01 8.68e-01
REACTOME SUMOYLATION OF SUMOYLATION PROTEINS 35 6.09e-01 -4.99e-02 8.70e-01
REACTOME MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS 7 6.11e-01 1.11e-01 8.70e-01
REACTOME SHC1 EVENTS IN ERBB4 SIGNALING 14 6.11e-01 -7.86e-02 8.70e-01
REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE 15 6.11e-01 -7.59e-02 8.70e-01
REACTOME POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE 25 6.12e-01 -5.86e-02 8.71e-01
REACTOME SIGNALING BY ALK 26 6.15e-01 5.70e-02 8.73e-01
REACTOME HUR ELAVL1 BINDS AND STABILIZES MRNA 8 6.15e-01 1.03e-01 8.73e-01
REACTOME L1CAM INTERACTIONS 112 6.16e-01 2.74e-02 8.73e-01
REACTOME PTK6 EXPRESSION 5 6.18e-01 1.29e-01 8.73e-01
REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III 31 6.18e-01 5.18e-02 8.73e-01
REACTOME GAP JUNCTION TRAFFICKING AND REGULATION 49 6.18e-01 4.12e-02 8.73e-01
REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION 59 6.18e-01 -3.75e-02 8.73e-01
REACTOME WAX AND PLASMALOGEN BIOSYNTHESIS 5 6.18e-01 1.29e-01 8.73e-01
REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN 37 6.19e-01 4.73e-02 8.73e-01
REACTOME REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO 10 6.19e-01 -9.09e-02 8.73e-01
REACTOME DEFECTIVE B4GALT1 CAUSES B4GALT1 CDG CDG 2D 8 6.22e-01 -1.01e-01 8.75e-01
REACTOME SMALL INTERFERING RNA SIRNA BIOGENESIS 9 6.22e-01 9.49e-02 8.75e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES 12 6.23e-01 -8.20e-02 8.75e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS 34 6.23e-01 4.87e-02 8.75e-01
REACTOME LATE SARS COV 2 INFECTION EVENTS 67 6.24e-01 3.46e-02 8.75e-01
REACTOME N GLYCAN ANTENNAE ELONGATION 15 6.25e-01 7.29e-02 8.75e-01
REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS 23 6.26e-01 5.88e-02 8.75e-01
REACTOME CA2 ACTIVATED K CHANNELS 9 6.26e-01 -9.38e-02 8.75e-01
REACTOME FLT3 SIGNALING THROUGH SRC FAMILY KINASES 6 6.26e-01 1.15e-01 8.75e-01
REACTOME RA BIOSYNTHESIS PATHWAY 22 6.27e-01 -5.99e-02 8.75e-01
REACTOME MHC CLASS II ANTIGEN PRESENTATION 121 6.27e-01 2.56e-02 8.75e-01
REACTOME LRR FLII INTERACTING PROTEIN 1 LRRFIP1 ACTIVATES TYPE I IFN PRODUCTION 5 6.27e-01 1.25e-01 8.75e-01
REACTOME SARS COV 2 TARGETS PDZ PROTEINS IN CELL CELL JUNCTION 5 6.27e-01 -1.25e-01 8.75e-01
REACTOME METABOLISM OF INGESTED SEMET SEC MESEC INTO H2SE 7 6.28e-01 -1.06e-01 8.75e-01
REACTOME NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 19 6.29e-01 6.41e-02 8.75e-01
REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND 21 6.29e-01 -6.08e-02 8.75e-01
REACTOME SIGNALING BY THE B CELL RECEPTOR BCR 106 6.30e-01 2.71e-02 8.75e-01
REACTOME RELEASE OF HH NP FROM THE SECRETING CELL 8 6.31e-01 9.82e-02 8.76e-01
REACTOME ABACAVIR TRANSMEMBRANE TRANSPORT 5 6.31e-01 1.24e-01 8.76e-01
REACTOME SYNTHESIS OF DOLICHYL PHOSPHATE 6 6.32e-01 1.13e-01 8.76e-01
REACTOME EICOSANOID LIGAND BINDING RECEPTORS 14 6.32e-01 7.39e-02 8.76e-01
REACTOME PLATELET HOMEOSTASIS 85 6.33e-01 3.00e-02 8.76e-01
REACTOME DSCAM INTERACTIONS 11 6.34e-01 8.28e-02 8.77e-01
REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS 118 6.35e-01 2.53e-02 8.77e-01
REACTOME ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN 13 6.35e-01 7.60e-02 8.77e-01
REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS 18 6.36e-01 6.44e-02 8.78e-01
REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS 16 6.37e-01 -6.82e-02 8.78e-01
REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM 50 6.38e-01 3.84e-02 8.79e-01
REACTOME OVARIAN TUMOR DOMAIN PROTEASES 36 6.39e-01 -4.52e-02 8.79e-01
REACTOME LYSOSPHINGOLIPID AND LPA RECEPTORS 14 6.39e-01 7.23e-02 8.79e-01
REACTOME ATTACHMENT AND ENTRY 16 6.40e-01 6.76e-02 8.79e-01
REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS 83 6.41e-01 -2.96e-02 8.80e-01
REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS 12 6.42e-01 7.76e-02 8.80e-01
REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS 100 6.43e-01 -2.68e-02 8.81e-01
REACTOME RIPK1 MEDIATED REGULATED NECROSIS 30 6.44e-01 -4.88e-02 8.81e-01
REACTOME AGGREPHAGY 42 6.44e-01 4.13e-02 8.81e-01
REACTOME SIGNALING BY MET 78 6.44e-01 -3.02e-02 8.81e-01
REACTOME SIGNALING BY FGFR2 IIIA TM 19 6.46e-01 6.08e-02 8.83e-01
REACTOME HOMOLOGY DIRECTED REPAIR 132 6.49e-01 -2.30e-02 8.83e-01
REACTOME DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE 30 6.49e-01 4.80e-02 8.83e-01
REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE 52 6.49e-01 -3.65e-02 8.83e-01
REACTOME PYRIMIDINE SALVAGE 10 6.49e-01 -8.31e-02 8.83e-01
REACTOME TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS 43 6.49e-01 -4.01e-02 8.83e-01
REACTOME TRANSCRIPTION OF THE HIV GENOME 66 6.49e-01 -3.24e-02 8.83e-01
REACTOME APOPTOSIS 173 6.51e-01 2.00e-02 8.83e-01
REACTOME REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION 9 6.51e-01 -8.70e-02 8.83e-01
REACTOME RECYCLING OF BILE ACIDS AND SALTS 18 6.51e-01 -6.15e-02 8.83e-01
REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS 12 6.52e-01 -7.52e-02 8.83e-01
REACTOME HISTIDINE CATABOLISM 8 6.53e-01 -9.19e-02 8.83e-01
REACTOME CREB3 FACTORS ACTIVATE GENES 8 6.53e-01 -9.18e-02 8.83e-01
REACTOME HCMV LATE EVENTS 110 6.54e-01 -2.47e-02 8.84e-01
REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE 16 6.56e-01 -6.44e-02 8.85e-01
REACTOME CONSTITUTIVE SIGNALING BY EGFRVIII 15 6.58e-01 -6.60e-02 8.87e-01
REACTOME HYALURONAN METABOLISM 17 6.58e-01 6.19e-02 8.87e-01
REACTOME FREE FATTY ACID RECEPTORS 5 6.59e-01 -1.14e-01 8.87e-01
REACTOME ACYL CHAIN REMODELING OF CL 5 6.60e-01 -1.14e-01 8.88e-01
REACTOME CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY 12 6.60e-01 7.33e-02 8.88e-01
REACTOME SIGNALING BY INTERLEUKINS 444 6.61e-01 1.21e-02 8.88e-01
REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE 63 6.62e-01 -3.19e-02 8.88e-01
REACTOME ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY 5 6.63e-01 1.13e-01 8.89e-01
REACTOME PTEN REGULATION 135 6.63e-01 2.17e-02 8.89e-01
REACTOME INTERACTION BETWEEN L1 AND ANKYRINS 30 6.64e-01 -4.59e-02 8.89e-01
REACTOME GLYCOSPHINGOLIPID METABOLISM 39 6.65e-01 4.01e-02 8.89e-01
REACTOME G ALPHA S SIGNALLING EVENTS 155 6.65e-01 2.02e-02 8.89e-01
REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS 8 6.67e-01 -8.79e-02 8.91e-01
REACTOME VITAMIN C ASCORBATE METABOLISM 8 6.68e-01 8.77e-02 8.91e-01
REACTOME SPHINGOLIPID METABOLISM 84 6.69e-01 -2.70e-02 8.91e-01
REACTOME STAT5 ACTIVATION 7 6.70e-01 -9.31e-02 8.91e-01
REACTOME TERMINATION OF TRANSLESION DNA SYNTHESIS 32 6.70e-01 -4.36e-02 8.91e-01
REACTOME MET ACTIVATES RAS SIGNALING 11 6.70e-01 -7.41e-02 8.91e-01
REACTOME HATS ACETYLATE HISTONES 129 6.71e-01 -2.17e-02 8.91e-01
REACTOME CYTOCHROME C MEDIATED APOPTOTIC RESPONSE 12 6.71e-01 -7.08e-02 8.91e-01
REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS 55 6.73e-01 3.29e-02 8.93e-01
REACTOME MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION 15 6.74e-01 -6.27e-02 8.93e-01
REACTOME ERBB2 REGULATES CELL MOTILITY 15 6.75e-01 -6.25e-02 8.93e-01
REACTOME SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS 14 6.75e-01 6.47e-02 8.93e-01
REACTOME VIRAL MESSENGER RNA SYNTHESIS 44 6.76e-01 -3.65e-02 8.93e-01
REACTOME LINOLEIC ACID LA METABOLISM 7 6.76e-01 9.13e-02 8.93e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES 29 6.77e-01 -4.47e-02 8.94e-01
REACTOME DIGESTION OF DIETARY CARBOHYDRATE 6 6.78e-01 9.79e-02 8.94e-01
REACTOME SIGNALLING TO P38 VIA RIT AND RIN 5 6.78e-01 -1.07e-01 8.94e-01
REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION 10 6.79e-01 7.55e-02 8.95e-01
REACTOME ROBO RECEPTORS BIND AKAP5 9 6.80e-01 -7.95e-02 8.95e-01
REACTOME SIGNALING BY MAPK MUTANTS 6 6.80e-01 9.71e-02 8.95e-01
REACTOME FATTY ACYL COA BIOSYNTHESIS 36 6.81e-01 3.96e-02 8.95e-01
REACTOME NETRIN 1 SIGNALING 49 6.82e-01 3.39e-02 8.95e-01
REACTOME HIV INFECTION 223 6.83e-01 -1.59e-02 8.95e-01
REACTOME MITOTIC TELOPHASE CYTOKINESIS 11 6.83e-01 -7.11e-02 8.95e-01
REACTOME ONCOGENE INDUCED SENESCENCE 35 6.83e-01 3.99e-02 8.95e-01
REACTOME INTERLEUKIN 36 PATHWAY 7 6.85e-01 8.84e-02 8.97e-01
REACTOME TLR3 MEDIATED TICAM1 DEPENDENT PROGRAMMED CELL DEATH 6 6.87e-01 -9.50e-02 8.99e-01
REACTOME METABOLISM OF CARBOHYDRATES 279 6.88e-01 -1.40e-02 8.99e-01
REACTOME SCAVENGING BY CLASS A RECEPTORS 19 6.88e-01 -5.31e-02 8.99e-01
REACTOME DNA DAMAGE BYPASS 47 6.90e-01 -3.36e-02 9.00e-01
REACTOME IRON UPTAKE AND TRANSPORT 56 6.91e-01 3.07e-02 9.00e-01
REACTOME EGFR INTERACTS WITH PHOSPHOLIPASE C GAMMA 9 6.91e-01 -7.66e-02 9.00e-01
REACTOME RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES 16 6.91e-01 5.74e-02 9.00e-01
REACTOME NERVOUS SYSTEM DEVELOPMENT 552 6.93e-01 -9.82e-03 9.02e-01
REACTOME RRNA PROCESSING IN THE MITOCHONDRION 9 6.94e-01 -7.57e-02 9.02e-01
REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING 26 6.94e-01 4.45e-02 9.02e-01
REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 11 6.95e-01 6.83e-02 9.02e-01
REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES 18 6.96e-01 5.32e-02 9.03e-01
REACTOME TRANSPORT OF FATTY ACIDS 8 6.98e-01 7.91e-02 9.05e-01
REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 19 7.00e-01 -5.11e-02 9.05e-01
REACTOME HEDGEHOG OFF STATE 111 7.00e-01 2.12e-02 9.05e-01
REACTOME KEAP1 NFE2L2 PATHWAY 104 7.02e-01 -2.17e-02 9.07e-01
REACTOME METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES 33 7.02e-01 3.84e-02 9.07e-01
REACTOME CELL CELL JUNCTION ORGANIZATION 64 7.03e-01 -2.75e-02 9.07e-01
REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE 20 7.04e-01 4.91e-02 9.07e-01
REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI 26 7.04e-01 4.30e-02 9.07e-01
REACTOME HEME DEGRADATION 15 7.04e-01 -5.66e-02 9.07e-01
REACTOME HS GAG DEGRADATION 19 7.06e-01 5.01e-02 9.08e-01
REACTOME GLYCOGEN METABOLISM 22 7.08e-01 -4.62e-02 9.09e-01
REACTOME ACYL CHAIN REMODELLING OF PC 27 7.08e-01 4.17e-02 9.09e-01
REACTOME INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE 20 7.08e-01 -4.84e-02 9.09e-01
REACTOME FORMATION OF APOPTOSOME 10 7.09e-01 -6.83e-02 9.09e-01
REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION 296 7.11e-01 -1.25e-02 9.11e-01
REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS 15 7.13e-01 -5.49e-02 9.13e-01
REACTOME ANDROGEN BIOSYNTHESIS 11 7.14e-01 -6.39e-02 9.13e-01
REACTOME SARS COV 1 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS 16 7.15e-01 -5.28e-02 9.13e-01
REACTOME NOD1 2 SIGNALING PATHWAY 33 7.15e-01 -3.67e-02 9.13e-01
REACTOME PROSTANOID LIGAND RECEPTORS 9 7.15e-01 -7.02e-02 9.13e-01
REACTOME INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING 103 7.15e-01 2.08e-02 9.13e-01
REACTOME CLEC7A INFLAMMASOME PATHWAY 6 7.16e-01 -8.56e-02 9.13e-01
REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING 13 7.19e-01 5.77e-02 9.15e-01
REACTOME ER QUALITY CONTROL COMPARTMENT ERQC 21 7.20e-01 -4.52e-02 9.16e-01
REACTOME HSF1 ACTIVATION 29 7.20e-01 -3.84e-02 9.16e-01
REACTOME GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION 14 7.21e-01 -5.51e-02 9.16e-01
REACTOME PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR 21 7.22e-01 4.48e-02 9.16e-01
REACTOME GENE SILENCING BY RNA 133 7.24e-01 1.77e-02 9.16e-01
REACTOME PREVENTION OF PHAGOSOMAL LYSOSOMAL FUSION 9 7.25e-01 -6.78e-02 9.16e-01
REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF 17 7.26e-01 -4.92e-02 9.16e-01
REACTOME CONDENSATION OF PROMETAPHASE CHROMOSOMES 11 7.26e-01 -6.10e-02 9.16e-01
REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX 15 7.26e-01 5.22e-02 9.16e-01
REACTOME CYTOPROTECTION BY HMOX1 59 7.27e-01 2.63e-02 9.16e-01
REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE 109 7.27e-01 -1.94e-02 9.16e-01
REACTOME TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE 20 7.27e-01 4.51e-02 9.16e-01
REACTOME TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX 14 7.27e-01 -5.39e-02 9.16e-01
REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY 23 7.27e-01 4.21e-02 9.16e-01
REACTOME GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER 25 7.31e-01 -3.97e-02 9.19e-01
REACTOME RND1 GTPASE CYCLE 41 7.31e-01 3.10e-02 9.19e-01
REACTOME SURFACTANT METABOLISM 28 7.32e-01 3.74e-02 9.19e-01
REACTOME EPITHELIAL MESENCHYMAL TRANSITION EMT DURING GASTRULATION 7 7.32e-01 7.48e-02 9.19e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST 18 7.32e-01 -4.66e-02 9.19e-01
REACTOME SIGNALING BY CSF3 G CSF 30 7.33e-01 -3.60e-02 9.19e-01
REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE 11 7.34e-01 5.93e-02 9.19e-01
REACTOME PURINE CATABOLISM 17 7.35e-01 -4.74e-02 9.19e-01
REACTOME SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS 74 7.36e-01 -2.27e-02 9.19e-01
REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION 35 7.36e-01 -3.30e-02 9.19e-01
REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION 23 7.36e-01 -4.06e-02 9.19e-01
REACTOME TRIF MEDIATED PROGRAMMED CELL DEATH 9 7.37e-01 6.45e-02 9.19e-01
REACTOMEMATURATION OF SARS COV 1 NUCLEOPROTEIN 11 7.38e-01 5.83e-02 9.19e-01
REACTOME DEFECTS IN VITAMIN AND COFACTOR METABOLISM 21 7.38e-01 4.22e-02 9.19e-01
REACTOME ACTIVATION OF RAC1 12 7.38e-01 5.58e-02 9.19e-01
REACTOME RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA 7 7.39e-01 -7.28e-02 9.19e-01
REACTOME SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER 15 7.39e-01 4.97e-02 9.19e-01
REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION 16 7.39e-01 4.80e-02 9.19e-01
REACTOME ERYTHROPOIETIN ACTIVATES RAS 14 7.43e-01 -5.07e-02 9.21e-01
REACTOME MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS 13 7.44e-01 -5.24e-02 9.21e-01
REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS 16 7.44e-01 -4.71e-02 9.21e-01
REACTOME SIGNAL ATTENUATION 10 7.45e-01 -5.95e-02 9.21e-01
REACTOME REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS 15 7.45e-01 -4.85e-02 9.21e-01
REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY 15 7.45e-01 -4.85e-02 9.21e-01
REACTOME GLUTATHIONE CONJUGATION 33 7.46e-01 -3.26e-02 9.21e-01
REACTOME BH3 ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI APOPTOTIC BCL 2 MEMBERS 9 7.46e-01 6.24e-02 9.21e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE 5 7.46e-01 8.36e-02 9.21e-01
REACTOME LAGGING STRAND SYNTHESIS 19 7.48e-01 -4.25e-02 9.23e-01
REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS 30 7.51e-01 3.35e-02 9.25e-01
REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS 16 7.51e-01 -4.58e-02 9.25e-01
REACTOME ESR MEDIATED SIGNALING 210 7.51e-01 1.27e-02 9.25e-01
REACTOME SIGNALING BY FLT3 FUSION PROTEINS 19 7.52e-01 4.18e-02 9.25e-01
REACTOME ENOS ACTIVATION 11 7.53e-01 -5.48e-02 9.25e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING 5 7.54e-01 8.10e-02 9.25e-01
REACTOME SIGNALING BY FLT3 ITD AND TKD MUTANTS 16 7.54e-01 -4.52e-02 9.25e-01
REACTOME RHO GTPASES ACTIVATE CIT 19 7.54e-01 4.15e-02 9.25e-01
REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS 39 7.55e-01 -2.89e-02 9.25e-01
REACTOME ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS 27 7.55e-01 3.47e-02 9.25e-01
REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS 11 7.57e-01 5.40e-02 9.26e-01
REACTOME RRNA MODIFICATION IN THE MITOCHONDRION 6 7.58e-01 7.25e-02 9.27e-01
REACTOME SUMOYLATION OF DNA REPLICATION PROTEINS 46 7.59e-01 2.61e-02 9.27e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER 28 7.60e-01 -3.33e-02 9.28e-01
REACTOME SYNTHESIS OF KETONE BODIES 8 7.61e-01 -6.20e-02 9.29e-01
REACTOME ANCHORING FIBRIL FORMATION 13 7.64e-01 4.80e-02 9.32e-01
REACTOME IRS ACTIVATION 5 7.65e-01 -7.71e-02 9.32e-01
REACTOME RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY 14 7.66e-01 -4.59e-02 9.33e-01
REACTOME FGFRL1 MODULATION OF FGFR1 SIGNALING 13 7.67e-01 4.74e-02 9.33e-01
REACTOME PCP CE PATHWAY 91 7.68e-01 1.79e-02 9.33e-01
REACTOME REGULATION OF LIPID METABOLISM BY PPARALPHA 115 7.69e-01 -1.59e-02 9.33e-01
REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3 59 7.69e-01 -2.21e-02 9.33e-01
REACTOME BASE EXCISION REPAIR 87 7.70e-01 -1.82e-02 9.33e-01
REACTOME NEGATIVE REGULATION OF ACTIVITY OF TFAP2 AP 2 FAMILY TRANSCRIPTION FACTORS 10 7.70e-01 -5.34e-02 9.33e-01
REACTOME DNA DOUBLE STRAND BREAK RESPONSE 74 7.72e-01 1.94e-02 9.35e-01
REACTOME VLDL CLEARANCE 6 7.73e-01 6.80e-02 9.35e-01
REACTOME TRAFFICKING OF AMPA RECEPTORS 29 7.73e-01 -3.09e-02 9.35e-01
REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES 77 7.74e-01 -1.89e-02 9.35e-01
REACTOME REGULATION OF NPAS4 GENE TRANSCRIPTION 5 7.75e-01 7.40e-02 9.35e-01
REACTOME PENTOSE PHOSPHATE PATHWAY 12 7.76e-01 -4.75e-02 9.35e-01
REACTOME SIGNALING BY ERYTHROPOIETIN 25 7.76e-01 3.29e-02 9.35e-01
REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI 17 7.76e-01 -3.98e-02 9.35e-01
REACTOME TAK1 DEPENDENT IKK AND NF KAPPA B ACTIVATION 41 7.78e-01 -2.54e-02 9.36e-01
REACTOME DECTIN 2 FAMILY 26 7.78e-01 3.19e-02 9.36e-01
REACTOME NEGATIVE REGULATION OF FLT3 15 7.79e-01 -4.19e-02 9.36e-01
REACTOME CS DS DEGRADATION 12 7.79e-01 -4.67e-02 9.36e-01
REACTOME PURINE SALVAGE 12 7.83e-01 4.59e-02 9.38e-01
REACTOME TRANSLESION SYNTHESIS BY POLH 19 7.84e-01 3.64e-02 9.38e-01
REACTOME REGULATION OF FZD BY UBIQUITINATION 21 7.84e-01 -3.45e-02 9.38e-01
REACTOME XENOBIOTICS 22 7.84e-01 -3.37e-02 9.38e-01
REACTOME DEFECTIVE CHST3 CAUSES SEDCJD 7 7.84e-01 5.97e-02 9.38e-01
REACTOME HS GAG BIOSYNTHESIS 28 7.84e-01 2.99e-02 9.38e-01
REACTOME DOWNSTREAM SIGNAL TRANSDUCTION 29 7.89e-01 2.87e-02 9.40e-01
REACTOME DISINHIBITION OF SNARE FORMATION 5 7.90e-01 -6.89e-02 9.40e-01
REACTOME TRANSLESION SYNTHESIS BY POLK 17 7.90e-01 -3.73e-02 9.40e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH METHYLATION 19 7.92e-01 3.50e-02 9.40e-01
REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING 29 7.92e-01 2.83e-02 9.40e-01
REACTOME TOLL LIKE RECEPTOR CASCADES 158 7.92e-01 1.22e-02 9.40e-01
REACTOME PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING 11 7.92e-01 -4.58e-02 9.40e-01
REACTOME VITAMINS 6 7.92e-01 6.21e-02 9.40e-01
REACTOME SIGNALING BY ERBB2 50 7.93e-01 -2.15e-02 9.40e-01
REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS 51 7.93e-01 -2.12e-02 9.40e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES 43 7.94e-01 2.31e-02 9.40e-01
REACTOME RMTS METHYLATE HISTONE ARGININES 72 7.94e-01 -1.78e-02 9.40e-01
REACTOME PI3K AKT ACTIVATION 9 7.94e-01 5.03e-02 9.40e-01
REACTOME APEX1 INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY 7 7.94e-01 -5.70e-02 9.40e-01
REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION 15 7.95e-01 3.88e-02 9.40e-01
REACTOME DEFECTIVE CHSY1 CAUSES TPBS 7 7.95e-01 -5.66e-02 9.40e-01
REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES 27 7.96e-01 -2.88e-02 9.40e-01
REACTOME TP53 REGULATES METABOLIC GENES 81 7.97e-01 1.65e-02 9.41e-01
REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 22 7.98e-01 -3.15e-02 9.41e-01
REACTOME CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND 9 8.00e-01 -4.88e-02 9.43e-01
REACTOME RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION 22 8.02e-01 3.08e-02 9.45e-01
REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE 37 8.04e-01 2.36e-02 9.47e-01
REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS 23 8.05e-01 2.97e-02 9.47e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS 15 8.07e-01 -3.65e-02 9.48e-01
REACTOME POLB DEPENDENT LONG PATCH BASE EXCISION REPAIR 8 8.08e-01 4.96e-02 9.49e-01
REACTOME DISEASES OF CARBOHYDRATE METABOLISM 31 8.09e-01 2.50e-02 9.50e-01
REACTOME PROCESSING OF SMDT1 16 8.10e-01 3.47e-02 9.50e-01
REACTOME NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10 12 8.11e-01 -3.98e-02 9.50e-01
REACTOME O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS 38 8.12e-01 2.24e-02 9.50e-01
REACTOME FASL CD95L SIGNALING 5 8.12e-01 6.13e-02 9.50e-01
REACTOME ORGANIC ANION TRANSPORTERS 10 8.13e-01 4.33e-02 9.50e-01
REACTOME ALPHA OXIDATION OF PHYTANATE 6 8.13e-01 5.58e-02 9.50e-01
REACTOME NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 11 8.14e-01 -4.10e-02 9.50e-01
REACTOME ESTROGEN DEPENDENT GENE EXPRESSION 140 8.14e-01 -1.15e-02 9.50e-01
REACTOME RAB GERANYLGERANYLATION 57 8.18e-01 -1.77e-02 9.53e-01
REACTOME DEPOLYMERISATION OF THE NUCLEAR LAMINA 14 8.18e-01 3.56e-02 9.53e-01
REACTOME GLUCAGON TYPE LIGAND RECEPTORS 32 8.19e-01 2.33e-02 9.54e-01
REACTOME TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS 52 8.19e-01 -1.83e-02 9.54e-01
REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES 29 8.21e-01 -2.43e-02 9.54e-01
REACTOME NONCANONICAL ACTIVATION OF NOTCH3 8 8.21e-01 -4.61e-02 9.54e-01
REACTOME FORMATION OF THE CORNIFIED ENVELOPE 125 8.22e-01 -1.16e-02 9.55e-01
REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE 21 8.24e-01 -2.80e-02 9.56e-01
REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE 63 8.24e-01 -1.62e-02 9.56e-01
REACTOME GRB2 EVENTS IN ERBB2 SIGNALING 16 8.25e-01 -3.19e-02 9.56e-01
REACTOME ERKS ARE INACTIVATED 13 8.27e-01 3.50e-02 9.56e-01
REACTOME COMMON PATHWAY OF FIBRIN CLOT FORMATION 21 8.28e-01 -2.75e-02 9.56e-01
REACTOME ACYL CHAIN REMODELLING OF PG 18 8.29e-01 -2.95e-02 9.56e-01
REACTOME MTORC1 MEDIATED SIGNALLING 23 8.29e-01 2.61e-02 9.56e-01
REACTOME ACTIVATION OF TRKA RECEPTORS 6 8.29e-01 5.10e-02 9.56e-01
REACTOME NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 25 8.29e-01 -2.49e-02 9.56e-01
REACTOME ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM 12 8.29e-01 3.59e-02 9.56e-01
REACTOME STAT3 NUCLEAR EVENTS DOWNSTREAM OF ALK SIGNALING 9 8.30e-01 4.13e-02 9.56e-01
REACTOME INTERLEUKIN 7 SIGNALING 31 8.32e-01 -2.20e-02 9.58e-01
REACTOME RHO GTPASES ACTIVATE ROCKS 19 8.33e-01 2.79e-02 9.58e-01
REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS 5 8.34e-01 5.41e-02 9.58e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION TERMINATION 23 8.34e-01 2.52e-02 9.58e-01
REACTOME PROCESSING OF DNA DOUBLE STRAND BREAK ENDS 93 8.35e-01 -1.25e-02 9.58e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS 9 8.35e-01 -4.02e-02 9.58e-01
REACTOME REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM 11 8.35e-01 3.62e-02 9.58e-01
REACTOME HOST INTERACTIONS OF HIV FACTORS 127 8.37e-01 1.06e-02 9.58e-01
REACTOME INTRAFLAGELLAR TRANSPORT 50 8.37e-01 -1.68e-02 9.58e-01
REACTOME MEIOTIC SYNAPSIS 73 8.37e-01 1.39e-02 9.58e-01
REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX 9 8.39e-01 -3.92e-02 9.59e-01
REACTOME TIGHT JUNCTION INTERACTIONS 29 8.40e-01 2.17e-02 9.59e-01
REACTOME TRANSCRIPTIONAL REGULATION BY TP53 351 8.40e-01 6.26e-03 9.60e-01
REACTOME HSF1 DEPENDENT TRANSACTIVATION 37 8.42e-01 -1.89e-02 9.60e-01
REACTOME NADE MODULATES DEATH SIGNALLING 5 8.43e-01 5.13e-02 9.60e-01
REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION 26 8.43e-01 2.24e-02 9.60e-01
REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING 12 8.44e-01 3.27e-02 9.60e-01
REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION 19 8.45e-01 -2.59e-02 9.60e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS 5 8.45e-01 -5.05e-02 9.60e-01
REACTOME PERK REGULATES GENE EXPRESSION 31 8.45e-01 -2.03e-02 9.60e-01
REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE 52 8.47e-01 -1.55e-02 9.62e-01
REACTOME TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE 39 8.50e-01 -1.75e-02 9.64e-01
REACTOME EGFR TRANSACTIVATION BY GASTRIN 9 8.51e-01 -3.62e-02 9.65e-01
REACTOME MASTL FACILITATES MITOTIC PROGRESSION 10 8.53e-01 3.39e-02 9.66e-01
REACTOME GAP JUNCTION ASSEMBLY 36 8.53e-01 -1.78e-02 9.66e-01
REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM 20 8.56e-01 -2.35e-02 9.68e-01
REACTOME MYOCLONIC EPILEPSY OF LAFORA 9 8.56e-01 -3.49e-02 9.68e-01
REACTOME RUNX2 REGULATES BONE DEVELOPMENT 29 8.56e-01 -1.94e-02 9.68e-01
REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES 38 8.58e-01 -1.67e-02 9.68e-01
REACTOME ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS 10 8.58e-01 -3.26e-02 9.68e-01
REACTOME RHO GTPASES ACTIVATE WASPS AND WAVES 34 8.58e-01 1.77e-02 9.68e-01
REACTOME IRAK1 RECRUITS IKK COMPLEX 12 8.59e-01 2.95e-02 9.68e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL 24 8.60e-01 2.08e-02 9.68e-01
REACTOME UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN 6 8.60e-01 4.15e-02 9.68e-01
REACTOME VITAMIN B2 RIBOFLAVIN METABOLISM 7 8.61e-01 3.83e-02 9.68e-01
REACTOME NEGATIVE REGULATION OF MAPK PATHWAY 41 8.63e-01 1.56e-02 9.68e-01
REACTOME IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN 5 8.63e-01 -4.45e-02 9.68e-01
REACTOME RAS SIGNALING DOWNSTREAM OF NF1 LOSS OF FUNCTION VARIANTS 7 8.63e-01 3.75e-02 9.68e-01
REACTOME SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS 12 8.64e-01 2.86e-02 9.68e-01
REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION 68 8.64e-01 -1.20e-02 9.68e-01
REACTOME NUCLEAR SIGNALING BY ERBB4 32 8.64e-01 1.75e-02 9.68e-01
REACTOME PHYSIOLOGICAL FACTORS 14 8.65e-01 -2.62e-02 9.69e-01
REACTOME HCMV INFECTION 152 8.66e-01 -7.93e-03 9.69e-01
REACTOME METALLOTHIONEINS BIND METALS 11 8.67e-01 2.91e-02 9.69e-01
REACTOME RHO GTPASE EFFECTORS 305 8.69e-01 -5.51e-03 9.70e-01
REACTOME INLA MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS 9 8.71e-01 3.14e-02 9.70e-01
REACTOME CHOLINE CATABOLISM 6 8.71e-01 3.83e-02 9.70e-01
REACTOME PROGRAMMED CELL DEATH 204 8.71e-01 -6.59e-03 9.70e-01
REACTOME DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS 25 8.72e-01 -1.87e-02 9.70e-01
REACTOME RECEPTOR MEDIATED MITOPHAGY 10 8.72e-01 2.94e-02 9.70e-01
REACTOME G2 M DNA DAMAGE CHECKPOINT 90 8.72e-01 -9.81e-03 9.70e-01
REACTOME ERYTHROPOIETIN ACTIVATES STAT5 7 8.73e-01 3.49e-02 9.70e-01
REACTOME PKMTS METHYLATE HISTONE LYSINES 64 8.74e-01 1.15e-02 9.70e-01
REACTOME INACTIVATION OF CSF3 G CSF SIGNALING 25 8.74e-01 -1.83e-02 9.70e-01
REACTOME NUCLEOTIDE SALVAGE 21 8.75e-01 1.98e-02 9.71e-01
REACTOME PHENYLALANINE METABOLISM 6 8.76e-01 -3.66e-02 9.72e-01
REACTOME INTERLEUKIN 12 SIGNALING 43 8.79e-01 1.34e-02 9.74e-01
REACTOME FCERI MEDIATED NF KB ACTIVATION 78 8.80e-01 9.90e-03 9.74e-01
REACTOME MATURATION OF SARS COV 1 SPIKE PROTEIN 5 8.81e-01 -3.85e-02 9.75e-01
REACTOME RNA POLYMERASE II PRE TRANSCRIPTION EVENTS 77 8.81e-01 -9.83e-03 9.75e-01
REACTOME E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS 58 8.84e-01 -1.11e-02 9.75e-01
REACTOME MET RECEPTOR ACTIVATION 6 8.84e-01 3.43e-02 9.75e-01
REACTOME INTERLEUKIN 12 FAMILY SIGNALING 53 8.85e-01 1.15e-02 9.75e-01
REACTOME RHOBTB2 GTPASE CYCLE 22 8.85e-01 1.78e-02 9.75e-01
REACTOME FLT3 SIGNALING IN DISEASE 28 8.86e-01 -1.57e-02 9.75e-01
REACTOME PI3K EVENTS IN ERBB2 SIGNALING 16 8.86e-01 -2.08e-02 9.75e-01
REACTOME INACTIVATION OF CDC42 AND RAC1 8 8.87e-01 -2.91e-02 9.76e-01
REACTOME INTERLEUKIN 21 SIGNALING 9 8.90e-01 2.67e-02 9.76e-01
REACTOME BETA CATENIN PHOSPHORYLATION CASCADE 16 8.90e-01 2.00e-02 9.76e-01
REACTOME DARPP 32 EVENTS 24 8.91e-01 1.61e-02 9.76e-01
REACTOME REACTIONS SPECIFIC TO THE COMPLEX N GLYCAN SYNTHESIS PATHWAY 10 8.92e-01 -2.48e-02 9.76e-01
REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE 71 8.92e-01 9.29e-03 9.76e-01
REACTOME NONHOMOLOGOUS END JOINING NHEJ 64 8.93e-01 9.70e-03 9.76e-01
REACTOME NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 22 8.93e-01 1.65e-02 9.76e-01
REACTOME INTERLEUKIN 1 FAMILY SIGNALING 146 8.93e-01 6.43e-03 9.76e-01
REACTOME DISEASES OF GLYCOSYLATION 137 8.94e-01 6.61e-03 9.76e-01
REACTOME SIGNALING BY RETINOIC ACID 41 8.94e-01 -1.20e-02 9.76e-01
REACTOME DEFECTIVE CHST6 CAUSES MCDC1 8 8.94e-01 2.71e-02 9.76e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD4 15 8.94e-01 -1.98e-02 9.76e-01
REACTOME SYNTHESIS OF 12 EICOSATETRAENOIC ACID DERIVATIVES 7 8.95e-01 -2.88e-02 9.76e-01
REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION 160 8.97e-01 -5.96e-03 9.77e-01
REACTOME RHOBTB GTPASE CYCLE 34 8.97e-01 1.28e-02 9.77e-01
REACTOME UNFOLDED PROTEIN RESPONSE UPR 88 8.98e-01 -7.93e-03 9.77e-01
REACTOME ACTIVATION OF SMO 18 8.98e-01 -1.75e-02 9.77e-01
REACTOME ABACAVIR ADME 9 8.99e-01 2.45e-02 9.77e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL 14 9.00e-01 1.94e-02 9.78e-01
REACTOME REGULATION OF NF KAPPA B SIGNALING 17 9.04e-01 -1.68e-02 9.82e-01
REACTOME DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE 17 9.09e-01 -1.61e-02 9.86e-01
REACTOME METABOLISM OF AMINE DERIVED HORMONES 17 9.09e-01 1.60e-02 9.86e-01
REACTOME MATURATION OF SARS COV 2 NUCLEOPROTEIN 15 9.09e-01 -1.70e-02 9.86e-01
REACTOME CLEC7A DECTIN 1 SIGNALING 97 9.10e-01 -6.65e-03 9.86e-01
REACTOME INNATE IMMUNE SYSTEM 1002 9.11e-01 2.08e-03 9.86e-01
REACTOME SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL 8 9.12e-01 2.25e-02 9.86e-01
REACTOME SYNTHESIS OF GDP MANNOSE 5 9.13e-01 -2.83e-02 9.86e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS 9 9.14e-01 -2.08e-02 9.86e-01
REACTOME REGULATION OF BACH1 ACTIVITY 11 9.14e-01 1.87e-02 9.86e-01
REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE 17 9.15e-01 1.49e-02 9.86e-01
REACTOME INTERLEUKIN 9 SIGNALING 7 9.16e-01 2.30e-02 9.86e-01
REACTOME PYRUVATE METABOLISM 29 9.17e-01 -1.12e-02 9.86e-01
REACTOME PROCESSING AND ACTIVATION OF SUMO 10 9.17e-01 -1.89e-02 9.86e-01
REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS 11 9.18e-01 -1.79e-02 9.86e-01
REACTOME ERK MAPK TARGETS 20 9.19e-01 1.32e-02 9.86e-01
REACTOME METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION 15 9.19e-01 -1.52e-02 9.86e-01
REACTOME DISEASES OF METABOLISM 237 9.19e-01 -3.81e-03 9.86e-01
REACTOME ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY 10 9.20e-01 -1.84e-02 9.86e-01
REACTOME FRUCTOSE CATABOLISM 5 9.20e-01 2.60e-02 9.86e-01
REACTOME TRANSPORT OF ORGANIC ANIONS 10 9.21e-01 -1.82e-02 9.86e-01
REACTOME RNA POLYMERASE III CHAIN ELONGATION 18 9.21e-01 1.35e-02 9.86e-01
REACTOME KETONE BODY METABOLISM 9 9.22e-01 1.89e-02 9.86e-01
REACTOME SUPPRESSION OF APOPTOSIS 7 9.22e-01 2.14e-02 9.86e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM 38 9.23e-01 9.03e-03 9.86e-01
REACTOME PROTEIN UBIQUITINATION 76 9.23e-01 6.39e-03 9.86e-01
REACTOME MAPK6 MAPK4 SIGNALING 91 9.24e-01 -5.81e-03 9.86e-01
REACTOME SYNTHESIS OF 15 EICOSATETRAENOIC ACID DERIVATIVES 6 9.26e-01 -2.20e-02 9.86e-01
REACTOME MITOCHONDRIAL CALCIUM ION TRANSPORT 23 9.26e-01 1.12e-02 9.86e-01
REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS 93 9.26e-01 -5.55e-03 9.86e-01
REACTOME PI3K EVENTS IN ERBB4 SIGNALING 10 9.27e-01 -1.67e-02 9.86e-01
REACTOME CYP2E1 REACTIONS 10 9.28e-01 1.66e-02 9.86e-01
REACTOME FGFR3B LIGAND BINDING AND ACTIVATION 7 9.28e-01 1.98e-02 9.86e-01
REACTOME PROTEIN FOLDING 96 9.28e-01 -5.33e-03 9.86e-01
REACTOME FRUCTOSE METABOLISM 7 9.28e-01 -1.97e-02 9.86e-01
REACTOME LTC4 CYSLTR MEDIATED IL4 PRODUCTION 6 9.29e-01 -2.11e-02 9.86e-01
REACTOME EPHA MEDIATED GROWTH CONE COLLAPSE 29 9.29e-01 9.54e-03 9.86e-01
REACTOME ACYL CHAIN REMODELLING OF PE 29 9.30e-01 -9.38e-03 9.86e-01
REACTOME DEFECTIVE EXT2 CAUSES EXOSTOSES 2 12 9.31e-01 -1.45e-02 9.86e-01
REACTOME NETRIN MEDIATED REPULSION SIGNALS 8 9.31e-01 -1.77e-02 9.86e-01
REACTOME ACTIVATION OF NIMA KINASES NEK9 NEK6 NEK7 7 9.34e-01 -1.81e-02 9.87e-01
REACTOME TNFR2 NON CANONICAL NF KB PATHWAY 96 9.35e-01 -4.85e-03 9.87e-01
REACTOME KERATAN SULFATE DEGRADATION 13 9.35e-01 1.31e-02 9.87e-01
REACTOME SHC RELATED EVENTS TRIGGERED BY IGF1R 9 9.35e-01 -1.57e-02 9.87e-01
REACTOME FORMATION OF LATERAL PLATE MESODERM 5 9.36e-01 2.08e-02 9.87e-01
REACTOME INTERLEUKIN 27 SIGNALING 11 9.39e-01 1.34e-02 9.90e-01
REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS 113 9.40e-01 4.10e-03 9.90e-01
REACTOME NGF INDEPENDANT TRKA ACTIVATION 5 9.40e-01 1.94e-02 9.90e-01
REACTOME PHASE 0 RAPID DEPOLARISATION 31 9.41e-01 -7.62e-03 9.90e-01
REACTOME LDL CLEARANCE 19 9.42e-01 9.67e-03 9.90e-01
REACTOME RESOLUTION OF ABASIC SITES AP SITES 38 9.42e-01 6.82e-03 9.90e-01
REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT 31 9.43e-01 7.43e-03 9.90e-01
REACTOME SUMOYLATION OF UBIQUITINYLATION PROTEINS 39 9.43e-01 6.61e-03 9.90e-01
REACTOME SIGNALING BY LRP5 MUTANTS 6 9.44e-01 1.65e-02 9.90e-01
REACTOME SOS MEDIATED SIGNALLING 7 9.44e-01 1.53e-02 9.90e-01
REACTOME RNA POLYMERASE II TRANSCRIBES SNRNA GENES 77 9.47e-01 -4.37e-03 9.92e-01
REACTOME CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION 11 9.47e-01 -1.15e-02 9.92e-01
REACTOME TRANSPORT AND SYNTHESIS OF PAPS 6 9.47e-01 -1.55e-02 9.92e-01
REACTOME AZATHIOPRINE ADME 22 9.48e-01 8.01e-03 9.92e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN 21 9.49e-01 -8.11e-03 9.92e-01
REACTOME RIBAVIRIN ADME 11 9.50e-01 -1.09e-02 9.92e-01
REACTOME DIGESTION AND ABSORPTION 22 9.50e-01 -7.68e-03 9.92e-01
REACTOME C TYPE LECTIN RECEPTORS CLRS 136 9.51e-01 3.08e-03 9.92e-01
REACTOME RHOBTB1 GTPASE CYCLE 22 9.53e-01 -7.31e-03 9.93e-01
REACTOME SODIUM CALCIUM EXCHANGERS 11 9.53e-01 1.02e-02 9.93e-01
REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX 57 9.54e-01 -4.46e-03 9.93e-01
REACTOME KSRP KHSRP BINDS AND DESTABILIZES MRNA 17 9.54e-01 -8.03e-03 9.93e-01
REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE 5 9.58e-01 1.36e-02 9.95e-01
REACTOME SMOOTH MUSCLE CONTRACTION 43 9.60e-01 -4.46e-03 9.95e-01
REACTOME RHOT1 GTPASE CYCLE 5 9.60e-01 -1.28e-02 9.95e-01
REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR 24 9.61e-01 5.82e-03 9.95e-01
REACTOME EARLY SARS COV 2 INFECTION EVENTS 34 9.61e-01 -4.88e-03 9.95e-01
REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS 42 9.61e-01 4.35e-03 9.95e-01
REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX 32 9.62e-01 -4.90e-03 9.95e-01
REACTOME RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK 47 9.62e-01 4.01e-03 9.95e-01
REACTOME NEUROTRANSMITTER RELEASE CYCLE 48 9.63e-01 -3.92e-03 9.95e-01
REACTOME SIGNALING BY PDGFR IN DISEASE 20 9.63e-01 5.93e-03 9.95e-01
REACTOME SIGNALING BY MST1 5 9.64e-01 -1.18e-02 9.95e-01
REACTOME REGULATED PROTEOLYSIS OF P75NTR 11 9.64e-01 7.92e-03 9.95e-01
REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE 17 9.64e-01 -6.31e-03 9.95e-01
REACTOME UBIQUINOL BIOSYNTHESIS 8 9.65e-01 8.99e-03 9.95e-01
REACTOME PASSIVE TRANSPORT BY AQUAPORINS 13 9.67e-01 -6.57e-03 9.97e-01
REACTOME RHO GTPASES ACTIVATE PKNS 86 9.68e-01 -2.52e-03 9.97e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE 5 9.68e-01 1.03e-02 9.97e-01
REACTOME BILE ACID AND BILE SALT METABOLISM 45 9.71e-01 3.15e-03 9.98e-01
REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING 25 9.73e-01 -3.97e-03 9.98e-01
REACTOME INTRA GOLGI TRAFFIC 43 9.73e-01 3.03e-03 9.98e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH RAS 9 9.74e-01 6.36e-03 9.98e-01
REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS 68 9.74e-01 2.32e-03 9.98e-01
REACTOME THE PHOTOTRANSDUCTION CASCADE 32 9.75e-01 -3.17e-03 9.98e-01
REACTOME SIGNALING BY RNF43 MUTANTS 8 9.76e-01 6.19e-03 9.98e-01
REACTOME DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX 83 9.76e-01 1.89e-03 9.98e-01
REACTOME TRAIL SIGNALING 8 9.76e-01 6.07e-03 9.98e-01
REACTOME PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1 9 9.77e-01 5.64e-03 9.98e-01
REACTOME SIGNALING BY PTK6 54 9.78e-01 -2.20e-03 9.98e-01
REACTOME COBALAMIN CBL METABOLISM 7 9.79e-01 -5.81e-03 9.98e-01
REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX 21 9.80e-01 3.22e-03 9.98e-01
REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING 6 9.80e-01 5.82e-03 9.98e-01
REACTOME POLYMERASE SWITCHING 13 9.81e-01 -3.73e-03 9.98e-01
REACTOME PREGNENOLONE BIOSYNTHESIS 12 9.83e-01 -3.64e-03 9.98e-01
REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX 14 9.83e-01 -3.25e-03 9.98e-01
REACTOME AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY 8 9.84e-01 -4.06e-03 9.98e-01
REACTOME CREB PHOSPHORYLATION 6 9.85e-01 4.32e-03 9.98e-01
REACTOME INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL 14 9.86e-01 2.76e-03 9.98e-01
REACTOME INTERLEUKIN 15 SIGNALING 13 9.86e-01 2.81e-03 9.98e-01
REACTOME MET RECEPTOR RECYCLING 10 9.86e-01 3.15e-03 9.98e-01
REACTOME SHC1 EVENTS IN ERBB2 SIGNALING 22 9.87e-01 2.00e-03 9.98e-01
REACTOME HDACS DEACETYLATE HISTONES 85 9.87e-01 -1.02e-03 9.98e-01
REACTOME RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX 29 9.87e-01 1.73e-03 9.98e-01
REACTOME SLC TRANSPORTER DISORDERS 94 9.87e-01 -9.42e-04 9.98e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH RAS 8 9.88e-01 -3.14e-03 9.98e-01
REACTOME PTK6 PROMOTES HIF1A STABILIZATION 6 9.88e-01 3.51e-03 9.98e-01
REACTOME CHYLOMICRON REMODELING 10 9.88e-01 2.71e-03 9.98e-01
REACTOME NEUROTOXICITY OF CLOSTRIDIUM TOXINS 10 9.89e-01 2.51e-03 9.98e-01
REACTOME UPTAKE OF DIETARY COBALAMINS INTO ENTEROCYTES 9 9.90e-01 2.51e-03 9.98e-01
REACTOME SIGNALING BY BMP 27 9.90e-01 -1.43e-03 9.98e-01
REACTOME HIV TRANSCRIPTION ELONGATION 42 9.90e-01 -1.06e-03 9.98e-01
REACTOME SEROTONIN NEUROTRANSMITTER RELEASE CYCLE 17 9.91e-01 -1.61e-03 9.98e-01
REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER 49 9.92e-01 -8.33e-04 9.98e-01
REACTOME DEFECTIVE CHST14 CAUSES EDS MUSCULOCONTRACTURAL TYPE 7 9.92e-01 2.17e-03 9.98e-01
REACTOME TNF SIGNALING 54 9.92e-01 -7.63e-04 9.98e-01
REACTOME COHESIN LOADING ONTO CHROMATIN 8 9.93e-01 1.80e-03 9.98e-01
REACTOME TRANS GOLGI NETWORK VESICLE BUDDING 67 9.95e-01 -4.53e-04 9.99e-01
REACTOME PEROXISOMAL LIPID METABOLISM 28 9.96e-01 5.10e-04 9.99e-01
REACTOME TELOMERE C STRAND SYNTHESIS INITIATION 12 9.97e-01 -7.16e-04 9.99e-01
REACTOME DNA DAMAGE REVERSAL 8 9.97e-01 -8.52e-04 9.99e-01
REACTOME TOLL LIKE RECEPTOR 9 TLR9 CASCADE 100 9.97e-01 -2.39e-04 9.99e-01
REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS 6 9.97e-01 8.03e-04 9.99e-01
REACTOME SELECTIVE AUTOPHAGY 79 9.98e-01 -1.81e-04 9.99e-01
REACTOME VISUAL PHOTOTRANSDUCTION 93 9.99e-01 -9.42e-05 9.99e-01
REACTOME TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS 36 9.99e-01 1.42e-04 9.99e-01


Detailed Gene set reports



REACTOME_TRANSLATION

REACTOME_TRANSLATION
1152
set REACTOME_TRANSLATION
setSize 278
pANOVA 3.16e-11
s.dist -0.231
p.adjustANOVA 5.19e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL10L -10791.0
RPS6 -10417.0
RPL10A -10270.0
PPA1 -10120.0
RPSA -9995.0
RPL15 -9935.0
RPS2 -9929.0
RPL36AL -9900.5
EIF4A2 -9888.0
RPL3 -9806.0
RPS13 -9755.0
SRP72 -9752.0
MRPS34 -9744.0
EIF3A -9731.0
RPL23 -9683.0
ERAL1 -9670.0
MRPS17 -9630.0
MRPL34 -9575.0
SPCS1 -9475.0
MRPS18A -9454.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL10L -10791.0
RPS6 -10417.0
RPL10A -10270.0
PPA1 -10120.0
RPSA -9995.0
RPL15 -9935.0
RPS2 -9929.0
RPL36AL -9900.5
EIF4A2 -9888.0
RPL3 -9806.0
RPS13 -9755.0
SRP72 -9752.0
MRPS34 -9744.0
EIF3A -9731.0
RPL23 -9683.0
ERAL1 -9670.0
MRPS17 -9630.0
MRPL34 -9575.0
SPCS1 -9475.0
MRPS18A -9454.0
RPL4 -9310.0
RPL22L1 -9170.0
RPL23A -9136.0
GARS1 -9110.0
EIF2S1 -9084.0
RPL18A -9066.0
EEF1B2 -9025.0
EIF3M -8950.0
EIF3K -8754.0
SEC61A1 -8692.0
MRPS24 -8684.0
MRPL46 -8636.0
MRPS33 -8522.0
RPL3L -8483.0
MRPL53 -8402.0
MRPL40 -8390.0
RPS8 -8297.0
RPL13 -8287.0
RPS11 -8218.0
N6AMT1 -8161.0
YARS2 -8053.0
RPLP1 -8007.0
TRAM1 -7990.0
MRPL16 -7970.0
RPL27 -7903.0
RPL26L1 -7810.0
MRPL19 -7795.0
AIMP2 -7777.0
MRPL21 -7761.0
NARS1 -7689.0
MRPS23 -7662.0
MRPS30 -7650.0
ETF1 -7512.0
RPL6 -7511.0
EIF2B2 -7487.0
RPL29 -7474.0
SRP9 -7453.0
OXA1L -7406.0
MRPL47 -7222.0
EIF2B5 -7165.0
RPS18 -7152.0
EEF1A2 -7075.0
EIF3G -7070.0
MRPL51 -7049.0
MRPL58 -7047.0
MRPL49 -6995.0
UBA52 -6801.0
MRPL10 -6732.0
DAP3 -6621.0
EIF2B4 -6519.0
RPS20 -6503.0
LARS1 -6454.0
EIF2S2 -6426.0
MRPS18C -6414.0
EIF3L -6407.0
RPS26 -6380.0
MRPS12 -6374.0
SARS2 -6336.0
FAU -6321.0
MARS2 -6308.0
RPL13A -6274.5
RPS7 -6226.0
MTIF3 -6202.0
EIF2B1 -6184.0
TSFM -6171.0
MRPS9 -6017.0
RPL26 -6001.0
MRPL3 -5920.0
MRPL18 -5791.0
EIF4H -5691.0
SPCS2 -5687.0
MRPS14 -5593.0
RPL39L -5553.0
RPL12 -5545.0
MRPL54 -5533.0
SEC61B -5498.0
RPL8 -5420.0
MRPS2 -5411.0
EIF5B -5401.0
SEC11A -5387.0
RARS2 -5340.0
RPS27L -5336.0
SEC11C -5294.0
RPLP0 -5288.0
MRPL50 -5259.0
RPS27A -5186.0
WARS2 -5177.0
SSR2 -5175.0
MRPL11 -5131.0
RPS16 -5010.0
MRPL39 -4844.0
HARS2 -4783.0
MRPL42 -4604.0
RARS1 -4602.0
EEF2 -4594.0
EIF4EBP1 -4579.0
RPL5 -4568.0
MRPS26 -4533.0
SRP54 -4531.0
MRPL37 -4525.0
RPS5 -4476.0
RPL32 -4474.0
RPS25 -4396.0
RPL28 -4371.0
EEF1A1 -4286.0
MTIF2 -4140.0
EPRS1 -4077.0
EIF5 -3917.0
MRPS15 -3887.0
RPL38 -3763.0
EIF3I -3533.0
EIF4A1 -3505.0
MRPL35 -3462.0
RPS21 -3340.0
RPL24 -3320.0
MRPL57 -3251.0
MTRF1L -3193.0
SEC61G -3182.0
MRPL52 -3108.0
EARS2 -3017.0
MRPL28 -3016.0
RPL35 -3005.0
MRPL32 -2998.0
KARS1 -2728.0
TRMT112 -2641.0
WARS1 -2627.0
SEC61A2 -2616.0
RPL21 -2532.0
EIF3F -2457.0
LARS2 -2360.0
MRPS18B -2330.0
RPS19 -2325.0
MRPL24 -2290.0
RPS29 -2223.0
MRPS7 -2194.0
EIF4G1 -2048.0
VARS2 -1957.0
RPL37 -1881.0
RPS9 -1875.0
RPL22 -1859.0
RPL18 -1836.0
GFM2 -1790.0
MRPL44 -1755.0
SRP14 -1602.0
SSR1 -1592.0
FARSB -1575.0
EIF3D -1554.0
FARS2 -1531.0
RPL17 -1516.0
MRPL17 -1472.0
MRPS28 -1421.0
EIF4B -1318.0
RPS12 -1300.0
IARS1 -1241.0
AARS1 -1209.0
MRPL27 -1190.0
MRPL12 -1168.0
IARS2 -1147.0
MRPS16 -1107.0
MRRF -1019.0
RPL7 -1014.0
SPCS3 -915.0
MRPS11 -657.0
SRPRB -547.0
MRPL15 -429.0
YARS1 -367.0
DDOST -289.0
MRPL20 -254.0
SRPRA -180.0
APEH -164.0
MRPL43 -77.0
TARS2 -40.0
MRPL9 41.0
MRPL30 141.0
EEF1E1 256.0
RPL27A 317.0
TUFM 548.0
PABPC1 575.0
MTFMT 590.0
RPS15A 633.0
MRPL2 639.0
EIF3E 663.0
MRPL38 769.0
RPS28 847.0
EIF3H 858.0
RPN1 916.0
PARS2 1182.0
RPL41 1186.0
MRPS35 1209.0
FARSA 1278.0
RPN2 1299.0
EIF3J 1346.0
RPS23 1371.0
MRPS22 1425.0
MRPL55 1458.0
MRPS5 1473.0
MRPS31 1491.0
MRPL48 1578.0
EIF4E 1594.0
RPS10 1817.0
RPS27 1846.0
SRP19 1906.0
RPS3 2010.0
MRPL1 2041.0
SSR3 2099.0
NARS2 2310.0
RPLP2 2399.0
RPL7A 2419.0
RPL37A 2421.0
RPS14 2461.0
AIMP1 2570.0
MRPL45 2649.0
MRPL14 2881.0
RPS24 2982.0
MRPS27 3037.0
RPL11 3088.0
MRPS6 3106.0
MRPL22 3193.0
EIF2B3 3217.0
RPL31 3319.0
HARS1 3376.0
AURKAIP1 3581.0
RPL9 3600.0
RPS15 3636.0
DARS2 3746.0
RPL34 3769.0
DARS1 3853.0
RPL30 3899.0
RPL36 4049.0
RPL14 4501.0
RPL19 4703.0
TARS1 4711.0
MRPL36 4832.0
RPL35A 4845.0
CHCHD1 4859.0
MRPS21 5457.0
MRPL4 5496.0
RPS3A 5749.0
SRP68 5766.0
CARS2 5865.0
GSPT1 5984.0
MRPL23 6003.0
EEF1D 6066.0
MRPL33 6377.0
MRPS10 6645.0
AARS2 6704.0
MRPS25 6871.0
PTCD3 6924.0
VARS1 7208.0
MARS1 7604.0
GADD45GIP1 7641.0
CARS1 7705.0
MRPL13 7779.0
GFM1 8612.0
PPA2 8808.0
EEF1G 8905.0
EIF3B 9606.0
MRPL41 9891.0


REACTOME_EUKARYOTIC_TRANSLATION_INITIATION

REACTOME_EUKARYOTIC_TRANSLATION_INITIATION
1149
set REACTOME_EUKARYOTIC_TRANSLATION_INITIATION
setSize 110
pANOVA 7.17e-09
s.dist -0.319
p.adjustANOVA 5.89e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL10L -10791.0
RPS6 -10417.0
RPL10A -10270.0
RPSA -9995.0
RPL15 -9935.0
RPS2 -9929.0
RPL36AL -9900.5
EIF4A2 -9888.0
RPL3 -9806.0
RPS13 -9755.0
EIF3A -9731.0
RPL23 -9683.0
RPL4 -9310.0
RPL22L1 -9170.0
RPL23A -9136.0
EIF2S1 -9084.0
RPL18A -9066.0
EIF3M -8950.0
EIF3K -8754.0
RPL3L -8483.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL10L -10791.0
RPS6 -10417.0
RPL10A -10270.0
RPSA -9995.0
RPL15 -9935.0
RPS2 -9929.0
RPL36AL -9900.5
EIF4A2 -9888.0
RPL3 -9806.0
RPS13 -9755.0
EIF3A -9731.0
RPL23 -9683.0
RPL4 -9310.0
RPL22L1 -9170.0
RPL23A -9136.0
EIF2S1 -9084.0
RPL18A -9066.0
EIF3M -8950.0
EIF3K -8754.0
RPL3L -8483.0
RPS8 -8297.0
RPL13 -8287.0
RPS11 -8218.0
RPLP1 -8007.0
RPL27 -7903.0
RPL26L1 -7810.0
RPL6 -7511.0
EIF2B2 -7487.0
RPL29 -7474.0
EIF2B5 -7165.0
RPS18 -7152.0
EIF3G -7070.0
UBA52 -6801.0
EIF2B4 -6519.0
RPS20 -6503.0
EIF2S2 -6426.0
EIF3L -6407.0
RPS26 -6380.0
FAU -6321.0
RPL13A -6274.5
RPS7 -6226.0
EIF2B1 -6184.0
RPL26 -6001.0
EIF4H -5691.0
RPL39L -5553.0
RPL12 -5545.0
RPL8 -5420.0
EIF5B -5401.0
RPS27L -5336.0
RPLP0 -5288.0
RPS27A -5186.0
RPS16 -5010.0
EIF4EBP1 -4579.0
RPL5 -4568.0
RPS5 -4476.0
RPL32 -4474.0
RPS25 -4396.0
RPL28 -4371.0
EIF5 -3917.0
RPL38 -3763.0
EIF3I -3533.0
EIF4A1 -3505.0
RPS21 -3340.0
RPL24 -3320.0
RPL35 -3005.0
RPL21 -2532.0
EIF3F -2457.0
RPS19 -2325.0
RPS29 -2223.0
EIF4G1 -2048.0
RPL37 -1881.0
RPS9 -1875.0
RPL22 -1859.0
RPL18 -1836.0
EIF3D -1554.0
RPL17 -1516.0
EIF4B -1318.0
RPS12 -1300.0
RPL7 -1014.0
RPL27A 317.0
PABPC1 575.0
RPS15A 633.0
EIF3E 663.0
RPS28 847.0
EIF3H 858.0
RPL41 1186.0
EIF3J 1346.0
RPS23 1371.0
EIF4E 1594.0
RPS10 1817.0
RPS27 1846.0
RPS3 2010.0
RPLP2 2399.0
RPL7A 2419.0
RPL37A 2421.0
RPS14 2461.0
RPS24 2982.0
RPL11 3088.0
EIF2B3 3217.0
RPL31 3319.0
RPL9 3600.0
RPS15 3636.0
RPL34 3769.0
RPL30 3899.0
RPL36 4049.0
RPL14 4501.0
RPL19 4703.0
RPL35A 4845.0
RPS3A 5749.0
EIF3B 9606.0


REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE

REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE
271
set REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE
setSize 105
pANOVA 7.65e-08
s.dist -0.304
p.adjustANOVA 4.18e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL10L -10791.0
RPS6 -10417.0
RPL10A -10270.0
RPSA -9995.0
RPL15 -9935.0
RPS2 -9929.0
RPL36AL -9900.5
RPL3 -9806.0
RPS13 -9755.0
SRP72 -9752.0
RPL23 -9683.0
SPCS1 -9475.0
RPL4 -9310.0
RPL22L1 -9170.0
RPL23A -9136.0
RPL18A -9066.0
SEC61A1 -8692.0
RPL3L -8483.0
RPS8 -8297.0
RPL13 -8287.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL10L -10791.0
RPS6 -10417.0
RPL10A -10270.0
RPSA -9995.0
RPL15 -9935.0
RPS2 -9929.0
RPL36AL -9900.5
RPL3 -9806.0
RPS13 -9755.0
SRP72 -9752.0
RPL23 -9683.0
SPCS1 -9475.0
RPL4 -9310.0
RPL22L1 -9170.0
RPL23A -9136.0
RPL18A -9066.0
SEC61A1 -8692.0
RPL3L -8483.0
RPS8 -8297.0
RPL13 -8287.0
RPS11 -8218.0
RPLP1 -8007.0
TRAM1 -7990.0
RPL27 -7903.0
RPL26L1 -7810.0
RPL6 -7511.0
RPL29 -7474.0
SRP9 -7453.0
RPS18 -7152.0
UBA52 -6801.0
RPS20 -6503.0
RPS26 -6380.0
FAU -6321.0
RPL13A -6274.5
RPS7 -6226.0
RPL26 -6001.0
SPCS2 -5687.0
RPL39L -5553.0
RPL12 -5545.0
SEC61B -5498.0
RPL8 -5420.0
SEC11A -5387.0
RPS27L -5336.0
SEC11C -5294.0
RPLP0 -5288.0
RPS27A -5186.0
SSR2 -5175.0
RPS16 -5010.0
RPL5 -4568.0
SRP54 -4531.0
RPS5 -4476.0
RPL32 -4474.0
RPS25 -4396.0
RPL28 -4371.0
RPL38 -3763.0
RPS21 -3340.0
RPL24 -3320.0
SEC61G -3182.0
RPL35 -3005.0
SEC61A2 -2616.0
RPL21 -2532.0
RPS19 -2325.0
RPS29 -2223.0
RPL37 -1881.0
RPS9 -1875.0
RPL22 -1859.0
RPL18 -1836.0
SRP14 -1602.0
SSR1 -1592.0
RPL17 -1516.0
RPS12 -1300.0
RPL7 -1014.0
SPCS3 -915.0
SRPRB -547.0
DDOST -289.0
SRPRA -180.0
RPL27A 317.0
RPS15A 633.0
RPS28 847.0
RPN1 916.0
RPL41 1186.0
RPN2 1299.0
RPS23 1371.0
RPS10 1817.0
RPS27 1846.0
SRP19 1906.0
RPS3 2010.0
SSR3 2099.0
RPLP2 2399.0
RPL7A 2419.0
RPL37A 2421.0
RPS14 2461.0
RPS24 2982.0
RPL11 3088.0
RPL31 3319.0
RPL9 3600.0
RPS15 3636.0
RPL34 3769.0
RPL30 3899.0
RPL36 4049.0
RPL14 4501.0
RPL19 4703.0
RPL35A 4845.0
RPS3A 5749.0
SRP68 5766.0


REACTOME_METABOLISM_OF_RNA

REACTOME_METABOLISM_OF_RNA
1313
set REACTOME_METABOLISM_OF_RNA
setSize 675
pANOVA 1.1e-07
s.dist -0.12
p.adjustANOVA 4.52e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
SF3B6 -10935
THOC3 -10883
RPL10L -10791
APOBEC1 -10789
NOP10 -10749
RRP9 -10654
TRMT12 -10459
RPS6 -10417
RRP7A -10373
RPL10A -10270
MPHOSPH10 -10209
DDX39A -10162
POP7 -10147
ZNF830 -10104
TRMT6 -10088
CLP1 -10054
CWC25 -10000
RPSA -9995
POLR2H -9976
PRPF19 -9962

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SF3B6 -10935.0
THOC3 -10883.0
RPL10L -10791.0
APOBEC1 -10789.0
NOP10 -10749.0
RRP9 -10654.0
TRMT12 -10459.0
RPS6 -10417.0
RRP7A -10373.0
RPL10A -10270.0
MPHOSPH10 -10209.0
DDX39A -10162.0
POP7 -10147.0
ZNF830 -10104.0
TRMT6 -10088.0
CLP1 -10054.0
CWC25 -10000.0
RPSA -9995.0
POLR2H -9976.0
PRPF19 -9962.0
PHF5A -9939.0
RPL15 -9935.0
RPS2 -9929.0
GTPBP3 -9917.0
RPL36AL -9900.5
EIF4A2 -9888.0
RPL3 -9806.0
YBX1 -9805.0
SF3B4 -9798.0
PCBP1 -9774.0
RBM22 -9769.0
RPS13 -9755.0
POLR2K -9746.0
SNRPE -9711.0
RPL23 -9683.0
UTP11 -9667.0
PSMB8 -9663.0
MPHOSPH6 -9644.0
GAR1 -9619.0
LCMT2 -9602.0
SNRPG -9530.0
GEMIN6 -9483.0
LSM7 -9469.0
CSTF2T -9464.0
POM121 -9356.0
PWP2 -9352.0
HNRNPH1 -9351.0
CACTIN -9330.0
RPL4 -9310.0
SF3A2 -9297.0
IMP3 -9187.0
RPL22L1 -9170.0
PSMB9 -9156.0
RPL23A -9136.0
CLNS1A -9132.0
RPL18A -9066.0
HNRNPA3 -9021.0
PPIH -9010.0
SLBP -8980.0
RBM8A -8942.0
PSMB6 -8884.0
POM121C -8815.0
PSMB11 -8782.0
XRN1 -8655.0
PSMC6 -8596.0
PRCC -8557.0
SNRPD3 -8507.0
RPL3L -8483.0
SMG1 -8480.0
XPO1 -8435.0
SNU13 -8416.0
CDK7 -8404.0
HNRNPA1 -8376.0
U2SURP -8324.0
DDX5 -8307.0
DIMT1 -8299.0
SEH1L -8298.0
RPS8 -8297.0
RPL13 -8287.0
DDX21 -8267.0
RPS11 -8218.0
TRMT13 -8199.0
RPPH1 -8133.0
C2orf49 -8128.0
HNRNPC -8124.0
CSTF1 -8086.0
DDX20 -8080.0
RPLP1 -8007.0
QTRT2 -7999.0
MAGOHB -7942.0
PSMB4 -7922.0
RPL27 -7903.0
THUMPD1 -7833.0
RPP25 -7830.0
RPL26L1 -7810.0
NUP155 -7766.0
FCF1 -7729.0
MTO1 -7568.0
PRPF38A -7546.0
HNRNPA2B1 -7545.0
PSMD12 -7515.0
ETF1 -7512.0
RPL6 -7511.0
CDC5L -7505.0
RPL29 -7474.0
GEMIN2 -7420.0
SMG7 -7366.0
TRMT10C -7360.0
ADAR -7355.0
PSMD9 -7320.0
EXOSC3 -7313.0
NOL12 -7280.0
LSM10 -7269.0
TP53RK -7265.0
PSMD14 -7231.0
ERCC3 -7188.0
PAIP1 -7158.0
RPS18 -7152.0
PPP2CA -7146.0
RIOK2 -7066.0
LSM8 -7039.0
SNRPA -6953.0
SAP18 -6922.0
UTP6 -6882.0
NUP58 -6850.0
TSR1 -6833.0
ZMAT5 -6817.0
CASC3 -6807.0
UBA52 -6801.0
NUDT21 -6760.0
PRPF6 -6722.0
SUGP1 -6712.0
LSM1 -6695.0
UTP4 -6688.0
WDR3 -6604.0
NUP54 -6598.0
ISY1 -6590.0
PSMD4 -6582.0
RPS20 -6503.0
TRMT5 -6473.0
RPS26 -6380.0
EFTUD2 -6358.0
FAU -6321.0
UBC -6316.0
HNRNPR -6277.0
RPL13A -6274.5
TNPO1 -6249.0
RPS7 -6226.0
PRORP -6165.0
DDX23 -6144.0
TRMT9B -6084.0
PNN -6076.0
TRDMT1 -6053.0
C9orf78 -6024.0
TYW1 -6005.0
RPL26 -6001.0
EXOSC2 -5983.0
SEC13 -5971.0
NOP14 -5963.0
TRMU -5923.0
CNOT6L -5867.0
NUP43 -5857.0
HSPA1A -5845.0
CNOT2 -5825.0
PSMD5 -5814.0
RNMT -5813.0
RRP36 -5769.0
NHP2 -5749.0
APOBEC4 -5717.0
LSM3 -5714.0
PPWD1 -5698.0
SNRPF -5670.0
PSME1 -5657.0
SRSF10 -5581.0
DHX9 -5565.0
PNO1 -5564.0
LUC7L3 -5561.0
NUP37 -5559.0
RPL39L -5553.0
RPL12 -5545.0
EXOSC1 -5502.0
NIP7 -5479.0
EIF4A3 -5476.0
PSMA2 -5475.0
CNOT8 -5458.0
PPP1R8 -5442.0
APOBEC3A -5439.0
RPL8 -5420.0
EXOSC6 -5407.0
SF3B1 -5393.0
GTF2H4 -5391.0
RIOK1 -5365.0
NOP56 -5347.0
RPS27L -5336.0
SEM1 -5318.0
HSPA8 -5301.0
RPLP0 -5288.0
DDX49 -5272.0
GTF2H1 -5193.0
TUT7 -5191.0
SF3B3 -5189.0
RPS27A -5186.0
SYMPK -5184.0
IGF2BP1 -5103.0
PPP2R1A -5096.0
RBM25 -5069.0
MAPK11 -5060.0
CNOT4 -5036.0
RPS16 -5010.0
NUP153 -4963.0
SDE2 -4953.0
SKIC3 -4948.0
SRSF9 -4869.0
POLR2I -4813.0
PSMA6 -4797.0
RPP30 -4776.0
TFIP11 -4715.0
PAN3 -4696.0
SNRNP35 -4692.0
GNL3 -4653.0
PSMB10 -4647.0
SNRPB -4640.0
SMG5 -4639.0
RPP14 -4580.0
PPIL3 -4577.0
RPL5 -4568.0
SET -4564.0
RNGTT -4506.0
RPS5 -4476.0
RPL32 -4474.0
TEX10 -4441.0
RPS25 -4396.0
SNRPA1 -4379.0
RPL28 -4371.0
ADAT2 -4345.0
CPSF6 -4344.0
NDC1 -4338.0
NCBP1 -4260.0
CSNK1E -4241.0
GEMIN5 -4166.0
ZNF473 -4136.0
MRM3 -4126.0
PABPN1 -4104.0
EXOSC5 -4103.0
EPRS1 -4077.0
YWHAZ -4048.0
OSGEP -4040.0
XRN2 -4024.0
PCF11 -3908.0
XPOT -3841.0
HNRNPF -3793.0
PSMC5 -3766.0
RPL38 -3763.0
GTF2H5 -3719.0
TNKS1BP1 -3684.0
IK -3655.0
PSMC3 -3596.0
TRIT1 -3557.0
DCAF13 -3553.0
TCERG1 -3538.0
PRPF3 -3534.0
SRSF3 -3525.0
DDX42 -3524.0
FAM98B -3518.0
EIF4A1 -3505.0
GEMIN7 -3503.0
CWF19L2 -3497.0
CTNNBL1 -3481.0
ZBTB8OS -3455.0
THOC5 -3445.0
CCNH -3426.0
SRSF5 -3406.0
UTP15 -3394.0
NOL6 -3365.0
RPS21 -3340.0
CNOT10 -3339.0
RPL24 -3320.0
POLR2D -3271.0
TPR -3264.0
SF3B2 -3228.0
DHX38 -3225.0
SNRPB2 -3156.0
DHX8 -3153.0
SRSF7 -3139.0
ZFP36L1 -3133.0
METTL14 -3113.0
ISG20L2 -3109.0
MNAT1 -3025.0
RPL35 -3005.0
PSMB1 -2993.0
SRSF11 -2953.0
GCFC2 -2921.0
SF3A1 -2906.0
SART1 -2881.0
BCAS2 -2843.0
TGS1 -2824.0
GTF2H3 -2808.0
BUD23 -2788.0
PSMD8 -2756.0
RNPS1 -2753.0
PSMB7 -2674.0
POP1 -2660.0
ADAT1 -2653.0
TRMT112 -2641.0
U2AF1L4 -2621.0
RNPC3 -2582.0
TRMT61A -2552.0
RPL21 -2532.0
TSEN15 -2530.0
PPIG -2506.0
WDR70 -2472.0
PSMD7 -2423.0
RBM28 -2409.0
ERI1 -2379.0
RANBP2 -2371.0
UTP3 -2346.0
NCL -2333.0
RPS19 -2325.0
DHX16 -2228.0
RPS29 -2223.0
PPIL4 -2222.0
DCP1A -2219.0
FAM32A -2189.0
DDX1 -2157.0
PUS3 -2153.0
EBNA1BP2 -2145.0
EIF4G1 -2048.0
NOL11 -2046.0
ACIN1 -2029.0
UTP14C -2028.0
DIS3 -2004.0
BUD31 -1982.0
PAPOLA -1974.0
A1CF -1944.0
THOC6 -1913.0
RPL37 -1881.0
CCAR1 -1876.0
RPS9 -1875.0
RTCB -1867.0
RPL22 -1859.0
RPL18 -1836.0
NUP98 -1787.0
DHX37 -1763.0
PSME4 -1747.0
SYF2 -1724.0
THOC7 -1578.0
NUP42 -1540.0
RPL17 -1516.0
GLE1 -1453.0
UTP18 -1393.0
DCPS -1353.0
SRSF1 -1326.0
DCP1B -1324.0
EIF4B -1318.0
RPS12 -1300.0
MTERF4 -1297.0
CNOT1 -1230.0
CTU1 -1229.0
APOBEC2 -1219.0
BUD13 -1034.0
RPL7 -1014.0
NAT10 -986.0
RPP40 -984.0
UTP25 -983.0
ALYREF -982.0
HNRNPK -960.0
SNRNP25 -908.0
DUS2 -817.0
LSM4 -715.0
TNFSF13 -678.0
DDX47 -661.0
WDR4 -641.0
HNRNPD -632.0
SRSF4 -623.0
UPF2 -618.0
NOB1 -609.0
EDC3 -564.0
POLR2A -529.0
NXT1 -520.0
NOC4L -475.0
IGF2BP3 -447.0
TSEN54 -426.0
MTREX -403.0
RBM39 -349.0
NUP214 -322.0
EXOSC4 -309.0
WDR18 -279.0
POLR2E -232.0
PSME3 -213.0
HNRNPU -203.0
CPSF2 -190.0
SNRPD2 -175.0
LSM6 -125.0
LSM2 -91.0
PRMT5 -87.0
MAPK14 -47.0
EXOSC8 -14.0
ERCC2 3.0
THADA 23.0
NUP88 31.0
MAPKAPK2 83.0
SNRNP200 97.0
PSMA8 102.0
PUS1 110.0
SNRPC 157.0
PDCD11 172.0
PSMB2 204.0
RBM7 216.0
SNRNP40 219.0
CNOT9 265.0
RPL27A 317.0
NSUN4 373.0
PSMD3 413.0
POLR2G 414.0
SNW1 435.0
TSEN34 445.0
PLRG1 462.0
FYTTD1 545.0
PAN2 561.0
PSMC1 563.0
PABPC1 575.0
FBL 589.0
SARNP 599.0
RPS15A 633.0
BYSL 670.0
SF3A3 721.0
NUP160 766.0
PSMC2 780.0
RCL1 783.0
SF3B5 819.0
MRM1 825.0
RPS28 847.0
MRM2 930.0
APOBEC3C 938.0
ELAC2 984.0
NSUN6 1052.0
PCBP2 1054.0
DDX46 1153.0
URM1 1154.0
RPL41 1186.0
GTF2F1 1188.0
POLR2C 1205.0
NUP50 1298.0
RPS23 1371.0
DDX6 1407.0
FTSJ3 1419.0
METTL3 1494.0
WDR33 1516.0
HNRNPL 1524.0
PSME2 1567.0
SMG9 1583.0
EIF4E 1594.0
PPIL1 1645.0
EMG1 1661.0
PSMF1 1681.0
PSMA4 1711.0
ALKBH8 1726.0
CPSF1 1736.0
NOP58 1756.0
PRPF40A 1773.0
RPS10 1817.0
THG1L 1823.0
RPP21 1829.0
NUP107 1840.0
SMN1 1844.5
SMN2 1844.5
RPS27 1846.0
HBS1L 1894.0
SNRNP48 1925.0
NT5C3B 1932.0
TYW3 1937.0
PTBP1 1959.0
BOP1 1994.0
PSMB5 1998.0
RPS3 2010.0
EXOSC10 2062.0
GEMIN4 2093.0
UPF3A 2101.0
CPSF4 2139.0
IMP4 2153.0
METTL1 2169.0
WDR75 2180.0
PPIE 2267.0
SF1 2274.0
PSMA7 2284.0
RPLP2 2399.0
RPL7A 2419.0
RPL37A 2421.0
NUP85 2441.0
EXOSC9 2446.0
RPS14 2461.0
YWHAB 2669.0
SNRNP27 2684.0
PELP1 2693.0
CDKAL1 2716.0
PSMD11 2717.0
AQR 2726.0
NOL9 2732.0
NSRP1 2744.0
TUT4 2889.0
WDR43 2974.0
RPS24 2982.0
LENG1 3013.0
SNRPN 3018.0
SRRM1 3023.0
DHX15 3043.0
PUS7 3084.0
RPL11 3088.0
WBP4 3104.0
UBL5 3152.0
RBM5 3168.0
RIOK3 3200.0
NOP2 3222.0
CWC27 3267.0
RBM42 3283.0
RPL31 3319.0
SENP3 3323.0
NUP205 3348.0
NUP62 3360.0
PRKCA 3441.0
PSMA3 3474.0
POLR2F 3481.0
CPSF3 3485.0
FUS 3508.0
PRKRIP1 3568.0
TRNT1 3578.0
RPL9 3600.0
RPS15 3636.0
SKIC2 3641.0
SNIP1 3670.0
U2AF2 3698.0
WTAP 3700.0
RPL34 3769.0
ZC3H11A 3770.0
NUP93 3792.0
SMG8 3867.0
NSUN2 3876.0
TRMT44 3878.0
RPL30 3899.0
PSMD1 3904.0
TRA2B 4014.0
RPL36 4049.0
NUP133 4054.0
APOBEC3B 4071.0
NCBP2 4072.0
DNAJC8 4120.0
EDC4 4168.0
WDR36 4187.0
LSM11 4216.0
PES1 4290.0
ANP32A 4292.0
KRR1 4298.0
ZCRB1 4438.0
UBB 4462.0
RPL14 4501.0
POP5 4529.0
XAB2 4562.0
TYW5 4565.0
GTF2F2 4584.0
PNRC2 4629.0
PHAX 4644.0
IGF2BP2 4702.0
RPL19 4703.0
YJU2 4707.0
TRMT61B 4736.0
PPP2R2A 4746.0
SNUPN 4767.0
DCP2 4792.0
DDX41 4799.0
SRSF6 4806.0
RPL35A 4845.0
SMU1 4939.0
DDX39B 4990.0
CWC22 4997.0
TRMT10A 5032.0
LSM5 5119.0
TRMT1 5180.0
RBM17 5204.0
TRMT11 5208.0
NXF1 5290.0
CPSF7 5304.0
SRRM2 5375.0
LTV1 5474.0
PRPF31 5486.0
USP39 5490.0
PRPF4 5506.0
DDX52 5531.0
SMNDC1 5534.0
APOBEC3H 5656.0
RTRAF 5701.0
AAAS 5713.0
SUPT5H 5722.0
PRPF18 5724.0
RPS3A 5749.0
RAE1 5767.0
TBL3 5786.0
WDR46 5790.0
PSMD2 5837.0
HNRNPM 5842.0
NUP188 5843.0
SRSF2 5973.0
TXNL4A 5981.0
GSPT1 5984.0
ZFP36 6017.0
CRNKL1 6036.0
PDCD7 6087.0
PARN 6152.0
CHTOP 6179.0
PATL1 6243.0
SKIC8 6267.0
PRKCD 6332.0
GPATCH1 6334.0
NUP35 6436.0
CNOT3 6468.0
CHERP 6518.0
CNOT6 6548.0
QTRT1 6565.0
HEATR1 6584.0
PSMA5 6687.0
SLU7 6756.0
FIP1L1 6972.0
MAGOH 7040.0
SRSF8 7081.0
POLR2B 7108.0
DHX35 7137.0
CNOT7 7156.0
PUF60 7166.0
MFAP1 7207.0
ADAT3 7215.0
AKT1 7231.0
TSEN2 7261.0
RRP1 7277.0
BMS1 7388.0
PSMC4 7451.0
UPF1 7470.0
RAN 7477.0
PSMD6 7550.0
TFB1M 7552.0
WBP11 7619.0
PSMA1 7633.0
THOC1 7678.0
PRPF8 7706.0
ADARB1 7707.0
SNRPD1 7715.0
SRRT 7790.0
CDC40 7841.0
TSR3 7851.0
UTP20 8000.0
EXOSC7 8019.0
POP4 8043.0
PPIL2 8071.0
KHSRP 8153.0
HSPB1 8184.0
ELAVL1 8257.0
CWC15 8369.0
WDR12 8382.0
PSMD13 8449.0
POLR2L 8498.0
CNOT11 8547.0
CSTF3 8605.0
C1D 8615.0
SMG6 8622.0
TPRKB 8668.0
PSMB3 8759.0
SRSF12 8784.0
ZMAT2 8797.0
CSNK1D 8903.0
RPP38 8998.0
CCDC12 9029.0
NUP210 9050.0
CTU2 9367.0
SNRNP70 9621.0
POLDIP3 9664.0
WDR77 9680.0
POLR2J 10513.0


REACTOME_RRNA_PROCESSING

REACTOME_RRNA_PROCESSING
1148
set REACTOME_RRNA_PROCESSING
setSize 192
pANOVA 3.45e-07
s.dist -0.213
p.adjustANOVA 0.000113



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL10L -10791.0
NOP10 -10749.0
RRP9 -10654.0
RPS6 -10417.0
RRP7A -10373.0
RPL10A -10270.0
MPHOSPH10 -10209.0
RPSA -9995.0
RPL15 -9935.0
RPS2 -9929.0
RPL36AL -9900.5
RPL3 -9806.0
RPS13 -9755.0
RPL23 -9683.0
UTP11 -9667.0
MPHOSPH6 -9644.0
GAR1 -9619.0
PWP2 -9352.0
RPL4 -9310.0
IMP3 -9187.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL10L -10791.0
NOP10 -10749.0
RRP9 -10654.0
RPS6 -10417.0
RRP7A -10373.0
RPL10A -10270.0
MPHOSPH10 -10209.0
RPSA -9995.0
RPL15 -9935.0
RPS2 -9929.0
RPL36AL -9900.5
RPL3 -9806.0
RPS13 -9755.0
RPL23 -9683.0
UTP11 -9667.0
MPHOSPH6 -9644.0
GAR1 -9619.0
PWP2 -9352.0
RPL4 -9310.0
IMP3 -9187.0
RPL22L1 -9170.0
RPL23A -9136.0
RPL18A -9066.0
RPL3L -8483.0
SNU13 -8416.0
DIMT1 -8299.0
RPS8 -8297.0
RPL13 -8287.0
DDX21 -8267.0
RPS11 -8218.0
RPLP1 -8007.0
RPL27 -7903.0
THUMPD1 -7833.0
RPP25 -7830.0
RPL26L1 -7810.0
FCF1 -7729.0
RPL6 -7511.0
RPL29 -7474.0
TRMT10C -7360.0
EXOSC3 -7313.0
NOL12 -7280.0
RPS18 -7152.0
RIOK2 -7066.0
UTP6 -6882.0
TSR1 -6833.0
UBA52 -6801.0
UTP4 -6688.0
WDR3 -6604.0
RPS20 -6503.0
RPS26 -6380.0
FAU -6321.0
RPL13A -6274.5
RPS7 -6226.0
PRORP -6165.0
RPL26 -6001.0
EXOSC2 -5983.0
NOP14 -5963.0
RRP36 -5769.0
NHP2 -5749.0
PNO1 -5564.0
RPL39L -5553.0
RPL12 -5545.0
EXOSC1 -5502.0
NIP7 -5479.0
RPL8 -5420.0
EXOSC6 -5407.0
RIOK1 -5365.0
NOP56 -5347.0
RPS27L -5336.0
RPLP0 -5288.0
DDX49 -5272.0
RPS27A -5186.0
RPS16 -5010.0
RPP30 -4776.0
GNL3 -4653.0
RPP14 -4580.0
RPL5 -4568.0
RPS5 -4476.0
RPL32 -4474.0
TEX10 -4441.0
RPS25 -4396.0
RPL28 -4371.0
CSNK1E -4241.0
MRM3 -4126.0
EXOSC5 -4103.0
XRN2 -4024.0
RPL38 -3763.0
DCAF13 -3553.0
UTP15 -3394.0
NOL6 -3365.0
RPS21 -3340.0
RPL24 -3320.0
ISG20L2 -3109.0
RPL35 -3005.0
BUD23 -2788.0
TRMT112 -2641.0
RPL21 -2532.0
RBM28 -2409.0
ERI1 -2379.0
UTP3 -2346.0
NCL -2333.0
RPS19 -2325.0
RPS29 -2223.0
EBNA1BP2 -2145.0
NOL11 -2046.0
UTP14C -2028.0
DIS3 -2004.0
RPL37 -1881.0
RPS9 -1875.0
RPL22 -1859.0
RPL18 -1836.0
DHX37 -1763.0
RPL17 -1516.0
UTP18 -1393.0
RPS12 -1300.0
MTERF4 -1297.0
RPL7 -1014.0
NAT10 -986.0
RPP40 -984.0
UTP25 -983.0
DDX47 -661.0
NOB1 -609.0
NOC4L -475.0
MTREX -403.0
EXOSC4 -309.0
WDR18 -279.0
EXOSC8 -14.0
PDCD11 172.0
RPL27A 317.0
NSUN4 373.0
FBL 589.0
RPS15A 633.0
BYSL 670.0
RCL1 783.0
MRM1 825.0
RPS28 847.0
MRM2 930.0
ELAC2 984.0
RPL41 1186.0
RPS23 1371.0
FTSJ3 1419.0
EMG1 1661.0
NOP58 1756.0
RPS10 1817.0
RPP21 1829.0
RPS27 1846.0
BOP1 1994.0
RPS3 2010.0
EXOSC10 2062.0
IMP4 2153.0
WDR75 2180.0
RPLP2 2399.0
RPL7A 2419.0
RPL37A 2421.0
EXOSC9 2446.0
RPS14 2461.0
PELP1 2693.0
NOL9 2732.0
WDR43 2974.0
RPS24 2982.0
RPL11 3088.0
RIOK3 3200.0
NOP2 3222.0
RPL31 3319.0
SENP3 3323.0
RPL9 3600.0
RPS15 3636.0
RPL34 3769.0
RPL30 3899.0
RPL36 4049.0
WDR36 4187.0
PES1 4290.0
KRR1 4298.0
RPL14 4501.0
RPL19 4703.0
RPL35A 4845.0
LTV1 5474.0
DDX52 5531.0
RPS3A 5749.0
TBL3 5786.0
WDR46 5790.0
HEATR1 6584.0
RRP1 7277.0
BMS1 7388.0
TFB1M 7552.0
TSR3 7851.0
UTP20 8000.0
EXOSC7 8019.0
WDR12 8382.0
C1D 8615.0
CSNK1D 8903.0
RPP38 8998.0


REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION

REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION
151
set REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION
setSize 87
pANOVA 1.24e-06
s.dist -0.301
p.adjustANOVA 0.000339



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL10L -10791.0
RPS6 -10417.0
RPL10A -10270.0
RPSA -9995.0
RPL15 -9935.0
RPS2 -9929.0
RPL36AL -9900.5
RPL3 -9806.0
RPS13 -9755.0
RPL23 -9683.0
RPL4 -9310.0
RPL22L1 -9170.0
RPL23A -9136.0
RPL18A -9066.0
EEF1B2 -9025.0
RPL3L -8483.0
RPS8 -8297.0
RPL13 -8287.0
RPS11 -8218.0
RPLP1 -8007.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL10L -10791.0
RPS6 -10417.0
RPL10A -10270.0
RPSA -9995.0
RPL15 -9935.0
RPS2 -9929.0
RPL36AL -9900.5
RPL3 -9806.0
RPS13 -9755.0
RPL23 -9683.0
RPL4 -9310.0
RPL22L1 -9170.0
RPL23A -9136.0
RPL18A -9066.0
EEF1B2 -9025.0
RPL3L -8483.0
RPS8 -8297.0
RPL13 -8287.0
RPS11 -8218.0
RPLP1 -8007.0
RPL27 -7903.0
RPL26L1 -7810.0
RPL6 -7511.0
RPL29 -7474.0
RPS18 -7152.0
EEF1A2 -7075.0
UBA52 -6801.0
RPS20 -6503.0
RPS26 -6380.0
FAU -6321.0
RPL13A -6274.5
RPS7 -6226.0
RPL26 -6001.0
RPL39L -5553.0
RPL12 -5545.0
RPL8 -5420.0
RPS27L -5336.0
RPLP0 -5288.0
RPS27A -5186.0
RPS16 -5010.0
EEF2 -4594.0
RPL5 -4568.0
RPS5 -4476.0
RPL32 -4474.0
RPS25 -4396.0
RPL28 -4371.0
EEF1A1 -4286.0
RPL38 -3763.0
RPS21 -3340.0
RPL24 -3320.0
RPL35 -3005.0
RPL21 -2532.0
RPS19 -2325.0
RPS29 -2223.0
RPL37 -1881.0
RPS9 -1875.0
RPL22 -1859.0
RPL18 -1836.0
RPL17 -1516.0
RPS12 -1300.0
RPL7 -1014.0
RPL27A 317.0
RPS15A 633.0
RPS28 847.0
RPL41 1186.0
RPS23 1371.0
RPS10 1817.0
RPS27 1846.0
RPS3 2010.0
RPLP2 2399.0
RPL7A 2419.0
RPL37A 2421.0
RPS14 2461.0
RPS24 2982.0
RPL11 3088.0
RPL31 3319.0
RPL9 3600.0
RPS15 3636.0
RPL34 3769.0
RPL30 3899.0
RPL36 4049.0
RPL14 4501.0
RPL19 4703.0
RPL35A 4845.0
RPS3A 5749.0
EEF1D 6066.0
EEF1G 8905.0


REACTOME_SELENOAMINO_ACID_METABOLISM

REACTOME_SELENOAMINO_ACID_METABOLISM
484
set REACTOME_SELENOAMINO_ACID_METABOLISM
setSize 108
pANOVA 2.05e-06
s.dist -0.264
p.adjustANOVA 0.000481



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL10L -10791.0
RPS6 -10417.0
RPL10A -10270.0
RPSA -9995.0
RPL15 -9935.0
RPS2 -9929.0
RPL36AL -9900.5
RPL3 -9806.0
RPS13 -9755.0
RPL23 -9683.0
RPL4 -9310.0
PSTK -9234.0
RPL22L1 -9170.0
RPL23A -9136.0
RPL18A -9066.0
SEPSECS -8502.0
RPL3L -8483.0
SCLY -8429.0
RPS8 -8297.0
RPL13 -8287.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL10L -10791.0
RPS6 -10417.0
RPL10A -10270.0
RPSA -9995.0
RPL15 -9935.0
RPS2 -9929.0
RPL36AL -9900.5
RPL3 -9806.0
RPS13 -9755.0
RPL23 -9683.0
RPL4 -9310.0
PSTK -9234.0
RPL22L1 -9170.0
RPL23A -9136.0
RPL18A -9066.0
SEPSECS -8502.0
RPL3L -8483.0
SCLY -8429.0
RPS8 -8297.0
RPL13 -8287.0
RPS11 -8218.0
HNMT -8170.0
RPLP1 -8007.0
RPL27 -7903.0
RPL26L1 -7810.0
AIMP2 -7777.0
TXNRD1 -7576.0
GNMT -7556.0
RPL6 -7511.0
RPL29 -7474.0
RPS18 -7152.0
UBA52 -6801.0
INMT -6794.0
RPS20 -6503.0
LARS1 -6454.0
RPS26 -6380.0
FAU -6321.0
RPL13A -6274.5
RPS7 -6226.0
RPL26 -6001.0
RPL39L -5553.0
RPL12 -5545.0
RPL8 -5420.0
RPS27L -5336.0
RPLP0 -5288.0
RPS27A -5186.0
RPS16 -5010.0
RARS1 -4602.0
RPL5 -4568.0
RPS5 -4476.0
RPL32 -4474.0
RPS25 -4396.0
RPL28 -4371.0
EPRS1 -4077.0
RPL38 -3763.0
RPS21 -3340.0
RPL24 -3320.0
RPL35 -3005.0
KARS1 -2728.0
RPL21 -2532.0
RPS19 -2325.0
RPS29 -2223.0
RPL37 -1881.0
RPS9 -1875.0
PAPSS1 -1861.0
RPL22 -1859.0
RPL18 -1836.0
RPL17 -1516.0
RPS12 -1300.0
IARS1 -1241.0
RPL7 -1014.0
CTH -864.0
SECISBP2 38.0
PAPSS2 62.0
EEF1E1 256.0
RPL27A 317.0
AHCY 390.0
RPS15A 633.0
RPS28 847.0
RPL41 1186.0
RPS23 1371.0
RPS10 1817.0
RPS27 1846.0
RPS3 2010.0
SEPHS2 2092.0
RPLP2 2399.0
RPL7A 2419.0
RPL37A 2421.0
RPS14 2461.0
AIMP1 2570.0
RPS24 2982.0
RPL11 3088.0
RPL31 3319.0
RPL9 3600.0
RPS15 3636.0
RPL34 3769.0
DARS1 3853.0
RPL30 3899.0
RPL36 4049.0
RPL14 4501.0
RPL19 4703.0
RPL35A 4845.0
RPS3A 5749.0
EEFSEC 7106.0
MARS1 7604.0
MAT1A 7805.0
NNMT 8062.0
GSR 8207.0


REACTOME_NONSENSE_MEDIATED_DECAY_NMD

REACTOME_NONSENSE_MEDIATED_DECAY_NMD
1443
set REACTOME_NONSENSE_MEDIATED_DECAY_NMD
setSize 107
pANOVA 3.13e-06
s.dist -0.261
p.adjustANOVA 0.000643



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL10L -10791.0
RPS6 -10417.0
RPL10A -10270.0
RPSA -9995.0
RPL15 -9935.0
RPS2 -9929.0
RPL36AL -9900.5
RPL3 -9806.0
RPS13 -9755.0
RPL23 -9683.0
RPL4 -9310.0
RPL22L1 -9170.0
RPL23A -9136.0
RPL18A -9066.0
RBM8A -8942.0
RPL3L -8483.0
SMG1 -8480.0
RPS8 -8297.0
RPL13 -8287.0
RPS11 -8218.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL10L -10791.0
RPS6 -10417.0
RPL10A -10270.0
RPSA -9995.0
RPL15 -9935.0
RPS2 -9929.0
RPL36AL -9900.5
RPL3 -9806.0
RPS13 -9755.0
RPL23 -9683.0
RPL4 -9310.0
RPL22L1 -9170.0
RPL23A -9136.0
RPL18A -9066.0
RBM8A -8942.0
RPL3L -8483.0
SMG1 -8480.0
RPS8 -8297.0
RPL13 -8287.0
RPS11 -8218.0
RPLP1 -8007.0
MAGOHB -7942.0
RPL27 -7903.0
RPL26L1 -7810.0
ETF1 -7512.0
RPL6 -7511.0
RPL29 -7474.0
SMG7 -7366.0
RPS18 -7152.0
PPP2CA -7146.0
CASC3 -6807.0
UBA52 -6801.0
RPS20 -6503.0
RPS26 -6380.0
FAU -6321.0
RPL13A -6274.5
RPS7 -6226.0
RPL26 -6001.0
RPL39L -5553.0
RPL12 -5545.0
EIF4A3 -5476.0
RPL8 -5420.0
RPS27L -5336.0
RPLP0 -5288.0
RPS27A -5186.0
PPP2R1A -5096.0
RPS16 -5010.0
SMG5 -4639.0
RPL5 -4568.0
RPS5 -4476.0
RPL32 -4474.0
RPS25 -4396.0
RPL28 -4371.0
NCBP1 -4260.0
RPL38 -3763.0
RPS21 -3340.0
RPL24 -3320.0
RPL35 -3005.0
RNPS1 -2753.0
RPL21 -2532.0
RPS19 -2325.0
RPS29 -2223.0
DCP1A -2219.0
EIF4G1 -2048.0
RPL37 -1881.0
RPS9 -1875.0
RPL22 -1859.0
RPL18 -1836.0
RPL17 -1516.0
RPS12 -1300.0
RPL7 -1014.0
UPF2 -618.0
RPL27A 317.0
PABPC1 575.0
RPS15A 633.0
RPS28 847.0
RPL41 1186.0
RPS23 1371.0
SMG9 1583.0
RPS10 1817.0
RPS27 1846.0
RPS3 2010.0
UPF3A 2101.0
RPLP2 2399.0
RPL7A 2419.0
RPL37A 2421.0
RPS14 2461.0
RPS24 2982.0
RPL11 3088.0
RPL31 3319.0
RPL9 3600.0
RPS15 3636.0
RPL34 3769.0
SMG8 3867.0
RPL30 3899.0
RPL36 4049.0
NCBP2 4072.0
RPL14 4501.0
PNRC2 4629.0
RPL19 4703.0
PPP2R2A 4746.0
RPL35A 4845.0
RPS3A 5749.0
GSPT1 5984.0
MAGOH 7040.0
UPF1 7470.0
SMG6 8622.0


REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES

REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES
1135
set REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES
setSize 353
pANOVA 5.08e-06
s.dist -0.141
p.adjustANOVA 0.00081



Top enriched genes

Top 20 genes
GeneID Gene Rank
SLC25A2 -10894.0
RPL10L -10791.0
TPH1 -10730.0
PDHA2 -10434.0
RPS6 -10417.0
RPL10A -10270.0
GCDH -10196.0
SLC6A12 -10126.0
AGXT -10100.0
CKMT1B -10061.0
ACMSD -10002.0
RPSA -9995.0
RPL15 -9935.0
RPS2 -9929.0
RPL36AL -9900.5
GCAT -9827.0
RPL3 -9806.0
RPS13 -9755.0
RPL23 -9683.0
PSMB8 -9663.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SLC25A2 -10894.0
RPL10L -10791.0
TPH1 -10730.0
PDHA2 -10434.0
RPS6 -10417.0
RPL10A -10270.0
GCDH -10196.0
SLC6A12 -10126.0
AGXT -10100.0
CKMT1B -10061.0
ACMSD -10002.0
RPSA -9995.0
RPL15 -9935.0
RPS2 -9929.0
RPL36AL -9900.5
GCAT -9827.0
RPL3 -9806.0
RPS13 -9755.0
RPL23 -9683.0
PSMB8 -9663.0
DLD -9434.0
MCCC2 -9430.0
RPL4 -9310.0
PSTK -9234.0
RPL22L1 -9170.0
PSMB9 -9156.0
GADL1 -9143.0
RPL23A -9136.0
HAL -9111.0
RPL18A -9066.0
PSMB6 -8884.0
PSMB11 -8782.0
SLC3A2 -8747.0
ODC1 -8724.0
PAH -8599.0
PSMC6 -8596.0
SEPSECS -8502.0
RPL3L -8483.0
AMD1 -8455.0
ECHS1 -8445.0
SCLY -8429.0
AANAT -8425.0
DIO1 -8364.0
TYR -8340.0
ADO -8306.0
RPS8 -8297.0
RPL13 -8287.0
ACADSB -8282.0
SLC25A21 -8263.0
RPS11 -8218.0
HNMT -8170.0
NQO1 -8166.0
SRM -8033.0
RPLP1 -8007.0
NAALAD2 -7982.0
PSMB4 -7922.0
RPL27 -7903.0
DCT -7883.0
RPL26L1 -7810.0
AIMP2 -7777.0
BHMT -7659.0
TXNRD1 -7576.0
GNMT -7556.0
PSMD12 -7515.0
RPL6 -7511.0
DLAT -7475.0
RPL29 -7474.0
SERINC1 -7456.0
PHGDH -7455.0
PRODH2 -7338.0
PSMD9 -7320.0
PSMD14 -7231.0
GATM -7210.0
RPS18 -7152.0
BCAT2 -6963.0
KYAT3 -6808.0
UBA52 -6801.0
INMT -6794.0
GOT2 -6787.0
PSMD4 -6582.0
MTRR -6534.0
RPS20 -6503.0
SRR -6481.0
LARS1 -6454.0
HOGA1 -6446.0
RPS26 -6380.0
FAU -6321.0
RPL13A -6274.5
FMO1 -6264.0
RPS7 -6226.0
HDC -6145.0
IDO2 -6083.0
RPL26 -6001.0
PSMD5 -5814.0
CDO1 -5704.0
PSME1 -5657.0
RPL39L -5553.0
RPL12 -5545.0
PSMA2 -5475.0
RPL8 -5420.0
RPS27L -5336.0
SEM1 -5318.0
GPT2 -5302.0
ARG1 -5299.0
PHYKPL -5295.0
RPLP0 -5288.0
KYAT1 -5277.0
RPS27A -5186.0
CRYM -5056.0
DAO -5021.0
RPS16 -5010.0
TPH2 -5004.0
ALDH18A1 -4887.0
BCKDK -4859.0
PSMA6 -4797.0
DUOX2 -4678.0
PSMB10 -4647.0
PSPH -4629.0
RARS1 -4602.0
RPL5 -4568.0
RPS5 -4476.0
RPL32 -4474.0
RIDA -4472.0
IYD -4406.0
RPS25 -4396.0
DHTKD1 -4383.0
RPL28 -4371.0
GOT1 -4275.0
ENOPH1 -4207.0
SLC25A15 -4165.0
GLS -4084.0
EPRS1 -4077.0
SERINC3 -3992.0
NAGS -3915.0
APIP -3898.0
PYCR1 -3883.0
CKMT2 -3877.0
SLC25A44 -3838.0
PSMC5 -3766.0
RPL38 -3763.0
BCAT1 -3723.0
PYCR2 -3665.0
PSMC3 -3596.0
TPO -3569.0
SLC25A13 -3530.0
CKM -3495.0
ACAT1 -3467.0
GLDC -3457.0
PXMP2 -3448.0
AGMAT -3391.0
RPS21 -3340.0
RPL24 -3320.0
TYRP1 -3247.0
SLC44A1 -3177.0
OCA2 -3105.0
GCSH -3046.0
RPL35 -3005.0
OAZ3 -2997.0
PSMB1 -2993.0
ASL -2836.0
PSMD8 -2756.0
HAO1 -2738.0
KARS1 -2728.0
PSMB7 -2674.0
RPL21 -2532.0
PSMD7 -2423.0
RPS19 -2325.0
MTAP -2313.0
LIPT2 -2274.0
NDUFAB1 -2243.0
AGXT2 -2241.0
RPS29 -2223.0
ALDH4A1 -2201.0
CPS1 -1999.0
SHMT1 -1959.0
RIMKLB -1949.0
PNMT -1903.0
RPL37 -1881.0
RPS9 -1875.0
PAPSS1 -1861.0
RPL22 -1859.0
RPL18 -1836.0
PSME4 -1747.0
HPD -1728.0
FTCD -1623.0
AZIN2 -1609.0
GLUD1 -1580.0
ADI1 -1545.0
LIPT1 -1541.0
RPL17 -1516.0
IDO1 -1502.0
SERINC2 -1438.0
ARG2 -1414.0
FOLH1 -1376.0
RPS12 -1300.0
IARS1 -1241.0
PDHX -1232.0
TSTD1 -1165.0
KMO -1164.0
RPL7 -1014.0
KYNU -946.0
ALDH7A1 -928.0
AADAT -907.0
CTH -864.0
DLST -821.0
AMT -788.0
PCBD1 -473.0
OGDH -356.0
GPT -311.0
PSME3 -213.0
QDPR -179.0
SECISBP2 38.0
BCKDHB 46.0
PAPSS2 62.0
ASPA 66.0
PSMA8 102.0
PSMB2 204.0
EEF1E1 256.0
RPL27A 317.0
ALDH9A1 370.0
AHCY 390.0
PSMD3 413.0
SQOR 443.0
ASNS 544.0
PSMC1 563.0
PSAT1 570.0
RPS15A 633.0
SLC36A4 734.0
PSMC2 780.0
RPS28 847.0
SLC25A12 957.0
HYKK 967.0
ACAD8 996.0
SLC45A2 1039.0
RPL41 1186.0
FAH 1194.0
SUOX 1354.0
RPS23 1371.0
OAT 1420.0
TXN2 1461.0
AUH 1470.0
PSME2 1567.0
PAOX 1650.0
PSMF1 1681.0
DDC 1684.0
PSMA4 1711.0
GLUL 1799.0
RPS10 1817.0
RPS27 1846.0
CSAD 1941.0
PSMB5 1998.0
RPS3 2010.0
HIBCH 2013.0
SEPHS2 2092.0
ETHE1 2143.0
NMRAL1 2154.0
SARDH 2240.0
PSMA7 2284.0
IL4I1 2295.0
RPLP2 2399.0
RPL7A 2419.0
RPL37A 2421.0
RPS14 2461.0
SLC6A11 2522.0
DBT 2527.0
AIMP1 2570.0
AFMID 2578.0
UROC1 2580.0
CHDH 2651.0
PSMD11 2717.0
BBOX1 2878.0
RPS24 2982.0
RPL11 3088.0
SLC6A7 3108.0
OAZ1 3260.0
TDO2 3301.0
RPL31 3319.0
SLC5A5 3392.0
MPST 3413.0
ASPG 3426.0
GRHPR 3427.0
PSMA3 3474.0
RPL9 3600.0
RPS15 3636.0
RIMKLA 3679.0
RPL34 3769.0
TSHB 3783.0
AZIN1 3839.0
DARS1 3853.0
RPL30 3899.0
PSMD1 3904.0
RPL36 4049.0
HGD 4086.0
AMDHD1 4112.0
CARNMT1 4191.0
DBH 4205.0
ASS1 4422.0
RPL14 4501.0
PDHB 4507.0
GLS2 4548.0
TH 4659.0
RPL19 4703.0
GSTZ1 4798.0
SMOX 4804.0
RPL35A 4845.0
TST 4894.0
TAT 5138.0
DIO2 5279.0
MCCC1 5349.0
OAZ2 5361.0
CARNS1 5372.0
PYCR3 5436.0
RPS3A 5749.0
SLC25A10 5800.0
MTR 5832.0
PSMD2 5837.0
LIAS 5880.0
DDO 6189.0
GAMT 6444.0
SDSL 6452.0
BHMT2 6520.0
MRI1 6537.0
HAAO 6553.0
AASS 6554.0
SERINC5 6612.0
PSMA5 6687.0
NAT8L 6698.0
DUOX1 6711.0
IVD 6750.0
ALDH6A1 6914.0
EEFSEC 7106.0
PSMC4 7451.0
PSMD6 7550.0
MARS1 7604.0
PSMA1 7633.0
BCKDHA 7714.0
MAT1A 7805.0
NNMT 8062.0
GSR 8207.0
PSMD13 8449.0
CKB 8628.0
PSMB3 8759.0
HIBADH 8831.0
DMGDH 8872.0
PPM1K 8904.0
DIO3 8969.0
ASRGL1 9286.0
SDS 9326.0
PIPOX 9425.0
SERINC4 9615.0
CGA 9886.0
PRODH 10017.0
SLC7A5 10514.0


REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY

REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY
1486
set REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY
setSize 94
pANOVA 5.09e-06
s.dist -0.272
p.adjustANOVA 0.00081



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL10L -10791.0
RPS6 -10417.0
RPL10A -10270.0
RPSA -9995.0
RPL15 -9935.0
RPS2 -9929.0
RPL36AL -9900.5
RPL3 -9806.0
RPS13 -9755.0
RPL23 -9683.0
RPL4 -9310.0
RPL22L1 -9170.0
RPL23A -9136.0
EIF2S1 -9084.0
RPL18A -9066.0
RPL3L -8483.0
RPS8 -8297.0
RPL13 -8287.0
RPS11 -8218.0
RPLP1 -8007.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL10L -10791.0
RPS6 -10417.0
RPL10A -10270.0
RPSA -9995.0
RPL15 -9935.0
RPS2 -9929.0
RPL36AL -9900.5
RPL3 -9806.0
RPS13 -9755.0
RPL23 -9683.0
RPL4 -9310.0
RPL22L1 -9170.0
RPL23A -9136.0
EIF2S1 -9084.0
RPL18A -9066.0
RPL3L -8483.0
RPS8 -8297.0
RPL13 -8287.0
RPS11 -8218.0
RPLP1 -8007.0
RPL27 -7903.0
RPL26L1 -7810.0
RPL6 -7511.0
RPL29 -7474.0
RPS18 -7152.0
ATF4 -6830.0
UBA52 -6801.0
RPS20 -6503.0
EIF2S2 -6426.0
RPS26 -6380.0
FAU -6321.0
RPL13A -6274.5
RPS7 -6226.0
RPL26 -6001.0
RPL39L -5553.0
RPL12 -5545.0
RPL8 -5420.0
RPS27L -5336.0
RPLP0 -5288.0
RPS27A -5186.0
RPS16 -5010.0
RPL5 -4568.0
RPS5 -4476.0
RPL32 -4474.0
RPS25 -4396.0
RPL28 -4371.0
ATF2 -4255.0
RPL38 -3763.0
RPS21 -3340.0
RPL24 -3320.0
IMPACT -3308.0
RPL35 -3005.0
RPL21 -2532.0
RPS19 -2325.0
RPS29 -2223.0
CEBPG -2139.0
RPL37 -1881.0
RPS9 -1875.0
RPL22 -1859.0
RPL18 -1836.0
RPL17 -1516.0
RPS12 -1300.0
RPL7 -1014.0
EIF2AK4 -366.0
RPL27A 317.0
ASNS 544.0
RPS15A 633.0
RPS28 847.0
RPL41 1186.0
RPS23 1371.0
RPS10 1817.0
RPS27 1846.0
RPS3 2010.0
ATF3 2115.0
RPLP2 2399.0
RPL7A 2419.0
RPL37A 2421.0
RPS14 2461.0
RPS24 2982.0
RPL11 3088.0
RPL31 3319.0
RPL9 3600.0
RPS15 3636.0
RPL34 3769.0
RPL30 3899.0
RPL36 4049.0
RPL14 4501.0
RPL19 4703.0
RPL35A 4845.0
GCN1 4991.0
RPS3A 5749.0
CEBPB 5972.0
DDIT3 7075.0
TRIB3 7514.0


REACTOME_INFLUENZA_INFECTION

REACTOME_INFLUENZA_INFECTION
228
set REACTOME_INFLUENZA_INFECTION
setSize 149
pANOVA 5.43e-06
s.dist -0.216
p.adjustANOVA 0.00081



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL10L -10791.0
KPNA7 -10650.0
RPS6 -10417.0
RPL10A -10270.0
CALR -10016.0
RPSA -9995.0
POLR2H -9976.0
ISG15 -9963.0
RPL15 -9935.0
RPS2 -9929.0
RPL36AL -9900.5
RPL3 -9806.0
RPS13 -9755.0
POLR2K -9746.0
RPL23 -9683.0
POM121 -9356.0
RPL4 -9310.0
RPL22L1 -9170.0
RPL23A -9136.0
RPL18A -9066.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL10L -10791.0
KPNA7 -10650.0
RPS6 -10417.0
RPL10A -10270.0
CALR -10016.0
RPSA -9995.0
POLR2H -9976.0
ISG15 -9963.0
RPL15 -9935.0
RPS2 -9929.0
RPL36AL -9900.5
RPL3 -9806.0
RPS13 -9755.0
POLR2K -9746.0
RPL23 -9683.0
POM121 -9356.0
RPL4 -9310.0
RPL22L1 -9170.0
RPL23A -9136.0
RPL18A -9066.0
CLTA -8953.0
POM121C -8815.0
RPL3L -8483.0
XPO1 -8435.0
SEH1L -8298.0
RPS8 -8297.0
RPL13 -8287.0
RPS11 -8218.0
KPNB1 -8106.0
RPLP1 -8007.0
RPL27 -7903.0
RPL26L1 -7810.0
NUP155 -7766.0
RPL6 -7511.0
RPL29 -7474.0
KPNA2 -7242.0
RPS18 -7152.0
IPO5 -7034.0
NUP58 -6850.0
UBA52 -6801.0
NUP54 -6598.0
RPS20 -6503.0
RPS26 -6380.0
FAU -6321.0
RPL13A -6274.5
RPS7 -6226.0
RPL26 -6001.0
SEC13 -5971.0
NUP43 -5857.0
HSPA1A -5845.0
HSP90AA1 -5799.0
NUP37 -5559.0
RPL39L -5553.0
RPL12 -5545.0
RPL8 -5420.0
RPS27L -5336.0
RPLP0 -5288.0
RPS27A -5186.0
RPS16 -5010.0
NUP153 -4963.0
POLR2I -4813.0
RPL5 -4568.0
RPS5 -4476.0
RPL32 -4474.0
RPS25 -4396.0
RPL28 -4371.0
NDC1 -4338.0
PABPN1 -4104.0
RPL38 -3763.0
RPS21 -3340.0
RPL24 -3320.0
POLR2D -3271.0
TPR -3264.0
KPNA1 -3170.0
RPL35 -3005.0
RPL21 -2532.0
RANBP2 -2371.0
KPNA5 -2326.0
RPS19 -2325.0
RPS29 -2223.0
RPL37 -1881.0
RPS9 -1875.0
RPL22 -1859.0
RPL18 -1836.0
NUP98 -1787.0
GRSF1 -1563.0
NUP42 -1540.0
RPL17 -1516.0
RPS12 -1300.0
RPL7 -1014.0
POLR2A -529.0
NUP214 -322.0
EIF2AK2 -283.0
POLR2E -232.0
NUP88 31.0
RPL27A 317.0
POLR2G 414.0
RPS15A 633.0
NUP160 766.0
CANX 806.0
RPS28 847.0
KPNA3 896.0
TGFB1 1028.0
RPL41 1186.0
GTF2F1 1188.0
POLR2C 1205.0
NUP50 1298.0
RPS23 1371.0
RPS10 1817.0
NUP107 1840.0
RPS27 1846.0
RPS3 2010.0
CPSF4 2139.0
RPLP2 2399.0
RPL7A 2419.0
RPL37A 2421.0
NUP85 2441.0
RPS14 2461.0
RPS24 2982.0
RPL11 3088.0
RPL31 3319.0
NUP205 3348.0
NUP62 3360.0
POLR2F 3481.0
RPL9 3600.0
RPS15 3636.0
RPL34 3769.0
NUP93 3792.0
RPL30 3899.0
KPNA4 3953.0
RPL36 4049.0
NUP133 4054.0
RPL14 4501.0
GTF2F2 4584.0
CLTC 4628.0
RPL19 4703.0
RPL35A 4845.0
AAAS 5713.0
RPS3A 5749.0
RAE1 5767.0
PARP1 5789.0
NUP188 5843.0
NUP35 6436.0
POLR2B 7108.0
RAN 7477.0
DNAJC3 8120.0
POLR2L 8498.0
NUP210 9050.0
POLR2J 10513.0


REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS

REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS
1364
set REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS
setSize 161
pANOVA 1.08e-05
s.dist -0.201
p.adjustANOVA 0.00148



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL10L -10791.0
RPS6 -10417.0
RPL10A -10270.0
RPSA -9995.0
RPL15 -9935.0
RPS2 -9929.0
RPL36AL -9900.5
RPL3 -9806.0
RPS13 -9755.0
RPL23 -9683.0
PSMB8 -9663.0
RPL4 -9310.0
RPL22L1 -9170.0
PSMB9 -9156.0
RPL23A -9136.0
RPL18A -9066.0
RBM8A -8942.0
PSMB6 -8884.0
PSMB11 -8782.0
PSMC6 -8596.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL10L -10791.0
RPS6 -10417.0
RPL10A -10270.0
RPSA -9995.0
RPL15 -9935.0
RPS2 -9929.0
RPL36AL -9900.5
RPL3 -9806.0
RPS13 -9755.0
RPL23 -9683.0
PSMB8 -9663.0
RPL4 -9310.0
RPL22L1 -9170.0
PSMB9 -9156.0
RPL23A -9136.0
RPL18A -9066.0
RBM8A -8942.0
PSMB6 -8884.0
PSMB11 -8782.0
PSMC6 -8596.0
RPL3L -8483.0
RPS8 -8297.0
RPL13 -8287.0
RPS11 -8218.0
RPLP1 -8007.0
MAGOHB -7942.0
PSMB4 -7922.0
RPL27 -7903.0
RPL26L1 -7810.0
ROBO3 -7535.0
PSMD12 -7515.0
ETF1 -7512.0
RPL6 -7511.0
RPL29 -7474.0
PSMD9 -7320.0
PSMD14 -7231.0
RPS18 -7152.0
CASC3 -6807.0
UBA52 -6801.0
PSMD4 -6582.0
RPS20 -6503.0
SLIT2 -6396.0
RPS26 -6380.0
FAU -6321.0
UBC -6316.0
RPL13A -6274.5
RPS7 -6226.0
RPL26 -6001.0
PSMD5 -5814.0
CUL2 -5781.0
PSME1 -5657.0
LHX2 -5609.0
ROBO2 -5579.0
RPL39L -5553.0
RPL12 -5545.0
EIF4A3 -5476.0
PSMA2 -5475.0
ROBO1 -5471.0
RPL8 -5420.0
RPS27L -5336.0
SEM1 -5318.0
RPLP0 -5288.0
LHX9 -5228.0
RPS27A -5186.0
RPS16 -5010.0
PSMA6 -4797.0
PSMB10 -4647.0
RPL5 -4568.0
RPS5 -4476.0
RPL32 -4474.0
RPS25 -4396.0
RPL28 -4371.0
NCBP1 -4260.0
PSMC5 -3766.0
RPL38 -3763.0
PSMC3 -3596.0
ELOC -3352.0
RPS21 -3340.0
RPL24 -3320.0
RPL35 -3005.0
PSMB1 -2993.0
PSMD8 -2756.0
RNPS1 -2753.0
PSMB7 -2674.0
RPL21 -2532.0
PSMD7 -2423.0
RPS19 -2325.0
HOXA2 -2284.0
RPS29 -2223.0
DAG1 -2199.0
EIF4G1 -2048.0
RPL37 -1881.0
RPS9 -1875.0
RPL22 -1859.0
RPL18 -1836.0
PSME4 -1747.0
RPL17 -1516.0
RPS12 -1300.0
RPL7 -1014.0
UPF2 -618.0
MSI1 -383.0
PSME3 -213.0
PSMA8 102.0
PSMB2 204.0
RPL27A 317.0
PSMD3 413.0
PSMC1 563.0
PABPC1 575.0
RPS15A 633.0
PSMC2 780.0
RPS28 847.0
RPL41 1186.0
RPS23 1371.0
PSME2 1567.0
PSMF1 1681.0
PSMA4 1711.0
RPS10 1817.0
RPS27 1846.0
PSMB5 1998.0
RPS3 2010.0
UPF3A 2101.0
LHX4 2259.0
PSMA7 2284.0
RPLP2 2399.0
RPL7A 2419.0
RPL37A 2421.0
RPS14 2461.0
PSMD11 2717.0
RPS24 2982.0
RPL11 3088.0
RPL31 3319.0
PSMA3 3474.0
RPL9 3600.0
RPS15 3636.0
RPL34 3769.0
RPL30 3899.0
PSMD1 3904.0
RPL36 4049.0
NCBP2 4072.0
USP33 4305.0
UBB 4462.0
LDB1 4490.0
RPL14 4501.0
RPL19 4703.0
RPL35A 4845.0
ISL1 5362.0
ELOB 5389.0
RPS3A 5749.0
PSMD2 5837.0
GSPT1 5984.0
RBX1 6251.0
PSMA5 6687.0
MAGOH 7040.0
PSMC4 7451.0
PSMD6 7550.0
PSMA1 7633.0
SLIT1 8142.0
LHX3 8326.0
PSMD13 8449.0
PSMB3 8759.0
ZSWIM8 10297.0


REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION
116
set REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION
setSize 291
pANOVA 3.38e-05
s.dist 0.141
p.adjustANOVA 0.00427



Top enriched genes

Top 20 genes
GeneID Gene Rank
CEACAM1 10746
KLK2 10585
LOXL4 10559
MATN3 10501
MMP20 10374
SCUBE3 10084
P4HB 9981
ASPN 9875
CD151 9731
MMP19 9661
LUM 9523
CAPN15 9430
ACTN1 9315
LAMA3 9262
COL23A1 9216
COL18A1 9137
LAMC2 9135
ITGB2 9130
CAPN14 9112
NCSTN 9094

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CEACAM1 10746
KLK2 10585
LOXL4 10559
MATN3 10501
MMP20 10374
SCUBE3 10084
P4HB 9981
ASPN 9875
CD151 9731
MMP19 9661
LUM 9523
CAPN15 9430
ACTN1 9315
LAMA3 9262
COL23A1 9216
COL18A1 9137
LAMC2 9135
ITGB2 9130
CAPN14 9112
NCSTN 9094
ITGAL 9076
ITGAX 9017
DMP1 8996
P3H3 8991
CAPN7 8971
FBN3 8885
FGG 8841
ITGB4 8834
ICAM3 8765
TNN 8630
FBN2 8556
BMP4 8336
SCUBE1 8300
AGRN 8273
MMP17 8228
LAMB2 8216
KLKB1 8125
ITGB6 8051
EFEMP2 7999
ITGAD 7880
COL8A2 7813
F11R 7755
CAPN5 7724
CTRB1 7690
ADAMTS5 7602
P4HA1 7555
COL6A6 7515
ITGB7 7439
COL20A1 7384
FGF2 7366
PLG 7357
TIMP2 7328
CAPNS2 7296
COL9A1 7270
COL24A1 7262
CRTAP 7217
ADAM12 7183
MFAP5 7160
LRP4 7129
TGFB3 6943
FGB 6886
CAPN8 6821
ITGA6 6810
FURIN 6735
JAM3 6700
COL6A5 6693
CAST 6662
CEACAM8 6614
LTBP3 6525
COL1A1 6443
ITGA5 6432
CTSG 6375
TMPRSS6 6336
BSG 6314
COL6A3 6307
ITGB5 6269
FBLN2 6265
ITGAE 6130
PLOD1 6094
MFAP4 6031
ICAM5 5890
EFEMP1 5879
MMP15 5764
FBLN1 5707
LOXL2 5663
MFAP2 5658
COL17A1 5572
P4HA2 5569
TGFB2 5394
EMILIN1 5388
ITGA4 5316
SDC1 5314
NCAN 5173
MMP10 5091
CTSB 5079
MMP7 5069
CDH1 5002
SDC3 4982
TTR 4977
LAMA5 4970
A2M 4959
CAPN12 4950
COL27A1 4861
COL16A1 4853
P3H2 4797
COL9A3 4732
TNXB 4667
VTN 4650
MADCAM1 4505
PCOLCE 4336
ITGB8 4314
SH3PXD2A 4097
CD44 4044
CAPN10 4012
ADAMTS4 3982
ITGA9 3968
PECAM1 3840
BMP7 3830
PLEC 3765
LAMA1 3607
TLL1 3564
MMP24 3535
CTSV 3499
MMP12 3475
NID1 3455
PCOLCE2 3443
PRKCA 3441
PDGFA 3410
COL19A1 3352
MATN1 3196
DDR1 3175
MMP25 3164
PPIB 3075
ADAMTS3 3004
FBLN5 2910
COL2A1 2875
HTRA1 2862
KDR 2848
COL12A1 2792
COL6A1 2783
DSPP 2725
ADAMTS18 2715
MMP14 2634
CAPN13 2594
COL4A3 2497
ITGAV 2311
LAMC3 2179
COL15A1 2042
ITGB1 2034
ITGA2 1940
ITGA2B 1909
SPOCK3 1896
ADAMTS2 1851
LOXL3 1747
EMILIN2 1708
COLGALT2 1636
ADAM10 1623
DST 1537
ADAM8 1520
LOX 1466
MFAP3 1293
VWF 1155
ADAMTS1 1105
TGFB1 1028
LTBP1 1009
CTSK 1007
COL4A4 972
COL4A2 837
CAPN1 827
APP 815
LTBP2 749
CD47 722
COL13A1 516
ITGB3 470
COMP 431
ADAM15 394
ICAM4 345
COL25A1 300
ADAMTS9 292
CTSD 187
TLL2 -7
COL5A1 -79
CTSS -89
ITGA10 -226
JAM2 -399
EMILIN3 -405
FN1 -458
SPARC -539
ITGA7 -593
CTSL -721
COL7A1 -873
PXDN -891
MUSK -1049
LAMB1 -1121
COL6A2 -1303
NTN4 -1311
HAPLN1 -1332
THBS1 -1415
ITGA8 -1528
ADAM17 -1542
CMA1 -1558
TRAPPC4 -1637
LOXL1 -1922
COL4A1 -2038
DAG1 -2199
PTPRS -2336
CAPN2 -2351
MMP2 -2424
CAPN3 -2485
COL5A3 -2601
VCAN -2725
CAPNS1 -2727
MMP9 -2732
NID2 -2736
ADAM19 -2737
P4HA3 -2740
COL11A2 -2784
MMP16 -2817
LAMC1 -2818
COL26A1 -3104
LTBP4 -3145
COL28A1 -3313
COL5A2 -3378
ITGA3 -3429
SDC2 -3458
BMP10 -3762
COL22A1 -3825
SERPINH1 -3828
ICAM1 -3910
HSPG2 -4093
COL8A1 -4149
SERPINE1 -4233
TNR -4296
MMP13 -4526
FGA -4581
FBN1 -4599
ADAMTS14 -4863
P3H1 -4881
ITGA11 -4933
BMP2 -4966
IBSP -4972
DDR2 -4991
COL21A1 -5002
COL3A1 -5013
ADAMTS16 -5075
ADAMTS8 -5093
MMP11 -5282
PHYKPL -5295
COLGALT1 -5355
COL9A2 -5363
COL14A1 -5382
ELN -5453
MATN4 -5618
NCAM1 -5793
PSEN1 -5917
CASP3 -6044
MMP1 -6319
PDGFB -6533
CAPN9 -6645
LAMA2 -6665
ITGA1 -6737
ACAN -6752
PLOD3 -6781
BMP1 -6878
TNC -6926
COL1A2 -7059
LAMA4 -7387
ADAM9 -7483
NRXN1 -7491
PLOD2 -8164
FMOD -8378
KLK7 -8407
GDF5 -8506
BCAN -8661
SDC4 -9074
CAPN11 -9205
PRSS1 -9421
CEACAM6 -9432
COL10A1 -9462
SPP1 -9636
DCN -9671
LAMB3 -10138
MMP8 -10281
MMP3 -10298
ICAM2 -10360
OPTC -10405
COL11A1 -10423
CTRB2 -10537
ELANE -10618
VCAM1 -10682
ITGAM -10716


REACTOME_RHO_GTPASE_CYCLE

REACTOME_RHO_GTPASE_CYCLE
1368
set REACTOME_RHO_GTPASE_CYCLE
setSize 423
pANOVA 4.77e-05
s.dist 0.115
p.adjustANOVA 0.0056



Top enriched genes

Top 20 genes
GeneID Gene Rank
LCK 10594
ARHGEF5 10564
ARAP3 10534
ARHGAP9 10444
CSK 10156
RAC2 10136
FGD3 9990
ANKFY1 9678
RAC3 9640
ARHGDIA 9595
SWAP70 9545
PREX1 9399
PLEKHG3 9378
WIPF2 9345
ACTN1 9315
NCF2 9191
ARHGAP45 9175
PLXND1 9167
TIAM2 9123
NIPSNAP2 9109

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
LCK 10594.0
ARHGEF5 10564.0
ARAP3 10534.0
ARHGAP9 10444.0
CSK 10156.0
RAC2 10136.0
FGD3 9990.0
ANKFY1 9678.0
RAC3 9640.0
ARHGDIA 9595.0
SWAP70 9545.0
PREX1 9399.0
PLEKHG3 9378.0
WIPF2 9345.0
ACTN1 9315.0
NCF2 9191.0
ARHGAP45 9175.0
PLXND1 9167.0
TIAM2 9123.0
NIPSNAP2 9109.0
FMNL3 9022.0
RHOB 8992.0
ARHGEF16 8962.0
PKN1 8915.0
DIAPH1 8803.0
GFOD1 8777.0
ARHGEF25 8637.0
CKB 8628.0
BASP1 8537.0
PLEKHG1 8497.0
DEF6 8490.0
DLG5 8483.0
MPP7 8346.0
MCAM 8290.0
CKAP4 8283.0
PIK3R1 8263.0
RAC1 8122.0
TAGAP 8114.0
ARHGEF4 8030.0
SRC 8026.0
WDR11 7916.0
CYFIP2 7899.0
ARHGDIG 7743.0
TRIO 7734.0
MYO9B 7729.0
RHOQ 7659.0
LRRC1 7628.0
IL32 7563.0
KCTD3 7522.0
PLEKHG2 7423.0
ANLN 7390.0
UBXN11 7387.0
BAIAP2 7360.0
ARHGAP1 7325.0
PLEKHG5 7232.0
PLEKHG6 7197.0
CYBA 7165.0
NCF4 7152.0
ACTC1 7022.0
PRAG1 6977.0
FRS2 6974.0
SPTBN1 6960.0
ARFGAP2 6876.0
PKN3 6822.0
TMOD3 6768.0
PAK2 6728.0
LAMTOR1 6683.0
HMOX2 6671.0
ZNF512B 6665.0
VAV2 6650.0
CDC42BPB 6616.0
ZAP70 6606.0
PAK6 6482.0
ABI1 6400.0
SOWAHC 6391.0
VIM 6338.0
DBN1 6288.0
ARHGAP18 6284.0
ARHGAP29 6274.0
STK10 6264.0
HINT2 6220.0
GRB7 6212.0
VCP 6187.0
CAPZB 6165.0
CDC42 6139.0
ROCK1 6122.0
VANGL2 6110.0
ARHGEF3 6082.0
ADD3 6079.0
SCRIB 6030.0
DOCK8 5975.0
GOLGA3 5966.0
HGS 5893.0
DOCK10 5883.0
PIK3R2 5878.0
MTR 5832.0
CDC42EP4 5792.0
SAMM50 5742.0
AAAS 5713.0
FNBP1L 5675.0
ARHGAP27 5610.0
DOCK2 5516.0
AMIGO2 5495.0
ARAP1 5425.0
DIAPH3 5410.0
CDC42EP2 5396.0
SH3BP1 5376.0
ARHGAP17 5355.0
DDRGK1 5346.0
CDC42EP3 5319.0
CPSF7 5304.0
WDR91 5293.0
MYO9A 5262.0
RAPGEF1 5230.0
ECT2 5168.0
ARAP2 5162.0
BCR 5105.0
ARHGEF7 5050.0
ARHGAP35 5006.0
DDX39B 4990.0
ABR 4989.0
RHOV 4966.0
ARHGEF2 4912.0
NISCH 4872.0
TNFAIP1 4811.0
TEX2 4787.0
WWP2 4735.0
DOCK5 4718.0
ARHGEF10L 4663.0
GARRE1 4642.0
CLTC 4628.0
ARHGDIB 4552.0
ARHGEF11 4551.0
SYDE1 4495.0
CUL3 4477.0
ARHGEF28 4434.0
PLXNB1 4371.0
GIT1 4166.0
YKT6 4146.0
SH3PXD2A 4097.0
PDE5A 4030.0
TRA2B 4014.0
ARHGAP11A 3954.0
ARHGEF1 3913.0
SLITRK5 3898.0
CDC42EP1 3895.0
IQGAP2 3894.0
ARHGEF17 3857.0
STMN2 3813.0
STEAP3 3812.0
RHOD 3756.0
ARHGEF10 3735.0
STK38 3734.0
WDR81 3635.0
AKAP12 3625.0
PAK5 3588.0
STIP1 3550.0
PLXNA1 3528.0
FARP2 3527.0
RHOBTB1 3515.0
SPATA13 3488.0
FARP1 3461.0
ARHGEF18 3385.0
CEP97 3350.0
NCK2 3285.0
ITSN1 3273.0
FERMT2 3266.0
RALGAPA1 3188.0
PTK2B 3156.0
NET1 3140.0
WASF2 3132.0
RHOU 3079.0
RHOH 3031.0
SRRM1 3023.0
GIT2 3008.0
DOCK3 3007.0
FAM13A 2997.0
PTPN13 2979.0
FLOT1 2832.0
STARD13 2826.0
PHIP 2751.0
FLOT2 2736.0
PLEKHG4 2648.0
CHN2 2603.0
KIDINS220 2553.0
DDX4 2544.0
DBT 2527.0
ARHGAP26 2510.0
SRGAP2 2475.0
ARHGAP12 2454.0
ARHGEF40 2435.0
TIAM1 2402.0
PLD2 2363.0
TPM3 2329.0
RND3 2324.0
ARFGAP3 2322.0
VANGL1 2301.0
PEAK1 2261.0
CCT2 2254.0
ARHGAP30 2223.0
NCKAP1 2220.0
NGEF 2216.0
ITGB1 2034.0
HSP90AB1 2011.0
GJA1 1691.0
PLD1 1626.0
CCDC115 1579.0
RHPN1 1563.0
DST 1537.0
CIT 1504.0
ALDH3A2 1478.0
ARHGAP33 1454.0
CCP110 1430.0
ARHGAP10 1428.0
ARHGAP15 1400.0
EMC3 1384.0
OBSCN 1267.0
ABCD3 1231.0
ITSN2 1210.0
SRGAP3 1202.0
TWF1 1195.0
RAB7A 1190.0
DOCK4 1148.0
VAPB 992.0
DOCK7 983.0
CCDC88A 977.0
AKAP13 883.0
SHKBP1 863.0
DAAM1 838.0
RASGRF2 804.0
FMNL2 767.0
FAM135A 742.0
PAK4 730.0
ARHGAP31 710.0
ARHGAP24 686.0
LBR 652.0
ROCK2 597.0
IQGAP1 580.0
DOCK1 571.0
WASF1 568.0
SYDE2 557.0
MSI2 487.0
ACBD5 422.0
WIPF1 416.0
EPHA2 327.0
GPS1 159.0
GRB2 152.0
WIPF3 113.0
SOS2 73.0
DSG2 65.0
ARHGEF15 39.0
ARHGAP21 -131.0
DSP -155.0
SH3RF1 -197.0
IQGAP3 -217.0
BAIAP2L2 -228.0
SLC4A7 -249.0
WHAMM -299.0
ARL13B -310.0
KALRN -313.0
TRIP10 -317.0
ARHGAP19 -410.0
FAM91A1 -418.0
KIF14 -543.0
TAOK3 -669.0
ACTB -701.0
BAIAP2L1 -729.0
PCDH7 -743.0
SNAP23 -766.0
PKP4 -819.0
VAV3 -820.0
SRGAP1 -859.0
ARHGAP32 -866.0
ANKRD26 -884.0
SPTAN1 -909.0
HSPE1 -926.0
PARD6B -933.0
RHPN2 -1043.0
SOS1 -1066.0
ELMO2 -1099.0
LMAN1 -1137.0
RND2 -1140.0
ABL2 -1151.0
EPSTI1 -1169.0
ARHGAP20 -1183.0
TFRC -1295.0
VAMP3 -1296.0
DEPDC1B -1325.0
ARHGAP23 -1331.0
RHOF -1346.0
SHMT2 -1366.0
FAM169A -1448.0
JAG1 -1574.0
NOX3 -1616.0
C1QBP -1647.0
BLTP3B -1719.0
NOXA1 -1765.0
ERBIN -1963.0
LETM1 -2003.0
EFHD2 -2024.0
SPEN -2064.0
NUDC -2181.0
ARHGEF26 -2193.0
ANKLE2 -2232.0
DOCK6 -2287.0
CAVIN1 -2315.0
KCTD13 -2354.0
DOCK9 -2439.0
RHOBTB2 -2460.0
WDR6 -2462.0
VAV1 -2494.0
SENP1 -2519.0
PAK1 -2523.0
ARHGAP5 -2571.0
MAP3K11 -2699.0
SCFD1 -2751.0
NSFL1C -2752.0
CFTR -2820.0
ARHGEF12 -2842.0
STBD1 -2888.0
ABI2 -2936.0
STOM -2954.0
MCF2L -3089.0
RASAL2 -3208.0
STX5 -3231.0
FNBP1 -3364.0
TJP2 -3388.0
RHOJ -3419.0
ARHGAP22 -3544.0
RACGAP1 -3568.0
FGD4 -3623.0
PIK3R3 -3645.0
BRK1 -3653.0
CPD -3662.0
CDC42EP5 -3692.0
PREX2 -3721.0
MTX1 -3745.0
STAM -3757.0
FAF2 -3800.0
KTN1 -3843.0
FRS3 -3874.0
ACTG1 -3920.0
MYO6 -4020.0
FMNL1 -4036.0
CDC42SE2 -4151.0
CPNE8 -4171.0
ALS2 -4210.0
COPS2 -4319.0
NCKAP1L -4346.0
TMEM87A -4566.0
RRAS2 -4596.0
CCT6A -4616.0
DNMBP -4809.0
NDUFA5 -4819.0
RTKN -4829.0
SLK -4834.0
FILIP1 -4856.0
PICALM -4886.0
PLEKHG4B -4889.0
GMIP -4890.0
NDUFS3 -4922.0
WASF3 -4929.0
ARHGAP8 -5135.0
CDC37 -5225.0
RALBP1 -5450.0
FGD2 -5484.0
RBBP6 -5515.0
LEMD3 -5529.0
UACA -5572.0
PIK3CA -5583.0
CDC42BPA -5597.0
CHN1 -5649.0
RND1 -5692.0
STAM2 -5765.0
FGD5 -5797.0
HSP90AA1 -5799.0
RHOA -5826.0
RNF20 -6079.0
PKN2 -6166.0
WASL -6172.0
ARHGAP28 -6317.0
MACO1 -6360.0
ARHGAP42 -6382.0
VRK2 -6563.0
GOPC -6565.0
RHOG -6637.0
ARHGAP44 -6782.0
CAV1 -6823.0
SLITRK3 -6861.0
OSBPL11 -6879.0
PGRMC2 -7028.0
PARD6A -7166.5
ARHGAP25 -7168.0
SLC1A5 -7239.0
NCK1 -7247.0
SEMA4F -7257.0
CCT7 -7312.0
TXNL1 -7462.0
CYFIP1 -7588.0
TMEM59 -7610.0
LMNB1 -7667.0
HNRNPC -8124.0
NOXO1 -8127.0
MUC13 -8138.0
DLC1 -8278.0
TMPO -8403.0
ARHGEF19 -8415.0
ESYT1 -8443.0
ARHGAP39 -8479.0
ARHGAP40 -8486.0
RHOC -8537.0
GNA13 -8637.0
COPS4 -8664.0
POTEE -8944.0
ARHGEF39 -9064.0
TUBA1B -9443.0
TOR1AIP1 -9457.0
ARHGAP11B -9488.0
FAM13B -9516.0
JUP -9734.0
TPM4 -9858.0
FAM83B -9891.0
DSG1 -10251.0


REACTOME_SIGNALING_BY_GPCR

REACTOME_SIGNALING_BY_GPCR
593
set REACTOME_SIGNALING_BY_GPCR
setSize 673
pANOVA 5.43e-05
s.dist 0.0912
p.adjustANOVA 0.00595



Top enriched genes

Top 20 genes
GeneID Gene Rank
TAS2R31 10842
CCL4 10786
GNB3 10775
SCT 10760
CXCR6 10754
CXCR5 10732
ADORA2A 10711
PLPPR3 10687
LPAR5 10678
CCL22 10676
CXCR1 10671
TAAR9 10574
CCL17 10571
AVP 10565
ARHGEF5 10564
CCL5 10535
GAST 10532
FZD9 10489
GPR183 10483
DRD4 10470

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TAS2R31 10842
CCL4 10786
GNB3 10775
SCT 10760
CXCR6 10754
CXCR5 10732
ADORA2A 10711
PLPPR3 10687
LPAR5 10678
CCL22 10676
CXCR1 10671
TAAR9 10574
CCL17 10571
AVP 10565
ARHGEF5 10564
CCL5 10535
GAST 10532
FZD9 10489
GPR183 10483
DRD4 10470
UTS2R 10394
ADORA3 10388
OXER1 10366
PROKR1 10278
SSTR3 10277
TAS2R46 10272
GNGT2 10236
ADCY7 10179
PPP1CA 10169
EDN2 10126
GHRH 10122
TAS2R60 10104
GNAS 10091
CCL21 10056
NPW 10052
TAAR8 10044
MLNR 10035
FGD3 9990
CHRM4 9984
HTR2B 9926
CGA 9886
NMUR1 9876
CCR7 9862
OPN1SW 9822
PTAFR 9677
NTSR2 9671
RGS14 9668
PTH2R 9659
TAAR5 9597
CCR9 9534
PRLH 9512
UCN 9497
DRD3 9488
PDPK1 9459
FFAR1 9445
UCN2 9427
TAS2R30 9409
CAMK2G 9407
PREX1 9399
GPR65 9375
WNT4 9369
SAA1 9319
CCL16 9300
ADRB1 9289
ACKR4 9288
CCR1 9255
DGKD 9193
PIK3R6 9156
TAAR6 9147
RXFP3 9143
TIAM2 9123
HTR1F 9070
PROK1 9005
RHOB 8992
ARHGEF16 8962
ARHGEF33 8873
TAS1R2 8861
TAS2R5 8778
TAS2R50 8731
ARHGEF37 8718
ARHGEF25 8637
TAS1R3 8560
PRKCQ 8542
CAMKK2 8519
ADRA1D 8499
P2RY12 8469
PSAP 8462
TRH 8461
DGKZ 8435
XCL1 8418
NPFFR1 8337
GNRH2 8325
GPR55 8311
PDE3B 8308
INSL3 8269
SSTR4 8266
PIK3R1 8263
ADM2 8260
NPY1R 8170
RGS11 8151
HCRT 8116
CXCL8 8056
GNAT1 8050
ARHGEF4 8030
SRC 8026
S1PR1 7995
GRM2 7992
GPHA2 7980
HTR1A 7969
RPS6KA2 7927
AKT2 7901
HBEGF 7888
PRKCH 7881
CX3CL1 7858
GRK6 7850
NTSR1 7844
TRIO 7734
LTB4R 7663
GNG4 7647
LPAR2 7618
TAS2R14 7610
RGS8 7568
PDE8B 7532
CMKLR1 7505
KNG1 7465
PIK3R5 7450
PLCB2 7436
PLEKHG2 7423
FZD7 7419
AKT3 7414
CXCL2 7402
PPBP 7394
PLPPR2 7358
S1PR3 7337
SST 7310
ADORA2B 7286
GRK2 7283
PLEKHG5 7232
AKT1 7231
RASGRP1 7200
TAS2R13 7175
PTH1R 7131
PPP2R1B 7101
CHRM3 7056
ABHD12 6985
C5 6958
AGTR1 6927
GPR18 6875
GNG12 6873
PPY 6797
CXCL12 6779
FZD8 6775
PLCB3 6772
CNR1 6738
LTB4R2 6712
BDKRB2 6686
FZD2 6669
VAV2 6650
NPY5R 6641
DGKA 6600
PPP2CB 6598
NMS 6545
TAS2R7 6514
GPSM1 6502
ITGA5 6432
P2RY14 6385
CCK 6337
PRKCD 6332
CX3CR1 6331
HTR6 6272
ADGRE5 6270
PTCH2 6260
GPR150 6202
P2RY13 6150
CDC42 6139
WNT3 6138
ROCK1 6122
ARHGEF3 6082
GNAI2 6080
RHO 6043
GHRL 6024
CCL27 5988
GPR20 5976
TAS2R19 5908
PMCH 5900
PIK3R2 5878
RGS10 5869
MGLL 5816
RGS1 5775
MLN 5760
PDE1B 5665
ADCY8 5635
PPP3CC 5628
GRK5 5618
QRFP 5613
ADRB3 5605
OPRM1 5596
APLNR 5576
ADRA2C 5570
OPN3 5547
GNAI1 5459
TAAR1 5448
GPBAR1 5437
ADCY4 5408
PPP1R1B 5406
NPBWR2 5284
ADCY9 5276
GPR25 5263
PDE7A 5219
ECT2 5168
NRAS 5054
ARHGEF7 5050
ABR 4989
CXCL1 4956
ECE1 4954
WNT8A 4916
ARHGEF2 4912
GPR4 4807
PTGDR2 4786
DAGLB 4783
WNT2 4743
GNG7 4722
SMO 4698
PNOC 4666
ARHGEF10L 4663
PTCH1 4655
CCKBR 4576
PDE4D 4554
ARHGEF11 4551
RGS17 4544
MAPK1 4404
ITPR2 4400
PLXNB1 4371
C3AR1 4356
F2R 4344
GNG2 4324
CAMK2B 4293
KISS1 4224
OXTR 4076
DHH 4064
CCL20 3980
GNB1 3921
ARHGEF1 3913
PRKAR1A 3893
CXCR2 3859
ARHGEF17 3857
ITPR3 3822
TSHB 3783
HCRTR2 3774
RASGRP2 3748
ARHGEF10 3735
MAPK3 3720
HTR1D 3690
GNA14 3646
ARRB1 3591
P2RY2 3575
GRK3 3529
WNT9B 3477
PRKCA 3441
RGS20 3389
ARHGEF18 3385
GALR2 3382
ADRA2B 3365
RRH 3354
HRH1 3349
GPR15 3327
POMC 3290
ITSN1 3273
GCG 3213
BDKRB1 3211
DGKQ 3144
NET1 3140
WNT10A 3121
PTGER3 3112
PLA2G4A 3000
CHRM1 2932
HTR4 2851
CAMKK1 2803
PRKACA 2802
PRKAR1B 2707
RGS13 2670
RXFP1 2572
HCAR2 2566
SSTR5 2531
CXCL5 2528
P2RY11 2526
WNT5A 2520
CCR10 2514
GPR176 2452
ARHGEF40 2435
PDE11A 2429
DGKH 2427
UCN3 2418
TIAM1 2402
LPAR1 2327
WNT11 2294
NGEF 2216
OXT 2213
GPR17 2198
DGKE 2167
NLN 2085
PDE7B 2077
WNT6 2070
GRM6 2046
ITGB1 2034
PDE8A 1987
PRKCB 1981
ITPR1 1953
HCRTR1 1951
CREB1 1922
GPR45 1900
TAS1R1 1890
GABBR1 1862
NMUR2 1855
HCAR1 1825
P2RY6 1690
CHRM5 1679
CALCR 1666
RGS19 1649
GPR83 1635
FZD6 1574
GNA15 1546
CCL2 1506
DGKG 1449
UTS2B 1446
PPP3R1 1437
FZD1 1397
PTGIR 1388
RGS4 1333
GNB5 1330
RGS7 1317
NMB 1308
RGS9 1305
OBSCN 1267
CAMK4 1256
RGS12 1238
P2RY1 1171
NBEA 1122
CCL23 1087
OPN4 1083
C5AR1 1078
CNR2 1062
ADCY1 1048
CXCL3 987
CXCL9 971
PTGDR 955
XCL2 931
GRM1 926
ACKR3 923
AKAP13 883
DGKI 864
TRPC6 840
APP 815
RASGRF2 804
ABHD6 796
TAS2R1 788
GNB4 731
MTNR1A 724
KRAS 718
RGSL1 717
GPR68 690
NPBWR1 665
GPR31 662
CCR6 645
ROCK2 597
ADRA1A 494
PTGFR 479
GNAQ 436
PENK 429
HTR1E 424
TBXA2R 391
C5AR2 362
RGR 361
GPR37 276
TRPC7 244
FSHR 201
GRB2 152
CASR 136
VIPR2 135
GPR32 132
SOS2 73
GNA12 71
ADCYAP1R1 50
ARHGEF15 39
GIPR 17
PRKAR2B -205
PRKCE -277
KALRN -313
EDN1 -380
OPN5 -424
PRKAR2A -455
FN1 -458
NPY2R -471
TAC1 -503
SCTR -522
PDE4B -574
ARHGEF38 -598
GNA11 -655
GPSM2 -688
ADRA1B -706
CCR8 -709
DAGLA -797
WNT9A -815
VAV3 -820
HRH2 -824
NPY -837
GIP -871
CCL19 -935
PCP2 -962
GPR27 -965
PRKACG -999
CCR3 -1031
GRM5 -1047
RGS3 -1050
TAS2R8 -1065
SOS1 -1066
WNT8B -1081
CALM1 -1130
ADCY5 -1182
ACKR1 -1188
EDNRA -1272
ADCY3 -1309
FFAR2 -1348
GABBR2 -1371
SSTR1 -1378
GNG13 -1387
CALCRL -1413
RGS16 -1432
OPRL1 -1451
PPP3CA -1564
FZD3 -1631
TAAR2 -1711
GRM8 -1741
GNG11 -1757
CORT -1802
F2RL2 -1888
DRD5 -1916
CCR2 -1920
CCR4 -1995
GPR35 -2083
QRFPR -2096
PF4 -2109
ADRA2A -2113
GNAZ -2115
ARHGEF26 -2193
RAMP1 -2200
HEBP1 -2203
F2 -2224
LHCGR -2250
GLP2R -2252
CXCL13 -2264
GPR39 -2327
AVPR1A -2345
GPSM3 -2357
LPAR6 -2404
DRD2 -2410
VAV1 -2494
CAMK2A -2499
PAK1 -2523
GNG5 -2583
OPRD1 -2624
PLCB1 -2655
EDNRB -2656
HTR7 -2657
PPP3CB -2745
HRAS -2839
ARHGEF12 -2842
ADGRE3 -2866
PIK3CG -2882
CRHR1 -2946
TACR3 -2950
TRHR -2952
MCF2L -3089
RGS6 -3242
ADORA1 -3322
WNT2B -3338
CXCR4 -3351
ADRB2 -3363
SHH -3380
GNAL -3434
NTS -3435
FZD5 -3539
NPFF -3558
PDE4C -3602
XCR1 -3614
FGD4 -3623
PIK3R3 -3645
PLCB4 -3654
ARRB2 -3663
TAS2R42 -3767
HRH3 -3829
VIP -3892
HTR1B -3896
ECE2 -3962
IHH -3972
CALCB -3996
RAMP3 -4029
EDN3 -4128
FPR3 -4193
GHSR -4198
RAMP2 -4278
WNT16 -4340
PRLHR -4410
VIPR1 -4411
GNAT3 -4448
ADCY6 -4455
CHRM2 -4459
LPAR3 -4467
PTHLH -4483
HTR2A -4504
GALR3 -4515
DRD1 -4548
MAPK7 -4549
MCHR2 -4636
GRP -4669
PDE2A -4673
PTGER4 -4689
WNT3A -4711
GPR84 -4729
ADGRE1 -4756
F2RL1 -4757
PRKACB -4770
WNT7B -4825
ADGRE2 -4835
PYY -4857
PTH2 -4862
PROK2 -4939
S1PR5 -4980
PLPPR4 -4982
F2RL3 -5009
PPP2R1A -5096
GPR37L1 -5170
FFAR4 -5176
GPER1 -5250
CCR5 -5260
CRH -5279
GAL -5324
PDE4A -5377
FGD2 -5484
GNG3 -5571
PIK3CA -5583
MC2R -5585
GPHB5 -5627
GRM3 -5634
PLPPR1 -5645
CALCA -5668
ADCY2 -5685
PDE3A -5689
ADM -5744
NMBR -5763
RHOA -5826
PPP2R5D -5910
KISS1R -5915
RLN3 -5940
RPS6KA1 -5945
CRHR2 -5947
TRPC3 -6012
GRM4 -6013
WNT7A -6111
RGS18 -6113
GNG10 -6129
PTGER2 -6158
CAMK2D -6272
GRM7 -6325
CXCL10 -6331
RGS2 -6482
S1PR2 -6566
CCRL2 -6618
GNAT2 -6683
GNB2 -6742
TSHR -6840
CCL28 -6964
AHCYL1 -7003
GPR132 -7051
IAPP -7110
PDE10A -7111
SSTR2 -7118
MC4R -7139
CXCL16 -7144
PPP2CA -7146
TAS2R16 -7176
TAS2R38 -7196
KPNA2 -7242
MC3R -7309
NMU -7370
TAS2R3 -7409
OXGR1 -7414
EGFR -7428
AVPR1B -7486
WNT1 -7490
GNAI3 -7543
CD55 -7609
TACR2 -7623
FZD10 -7636
SUCNR1 -7640
PRKCG -7785
PLPPR5 -7832
PTGER1 -8005
OPRK1 -8019
NPSR1 -8040
FSHB -8051
CXCL11 -8089
TAS2R20 -8100
DGKB -8102
NPB -8189
GNGT1 -8192
PDE1C -8196
GNRH1 -8256
RGS22 -8266
HTR5A -8271
PTH -8374
C3 -8377
INSL5 -8397
ARHGEF19 -8415
TAS2R40 -8464
WNT10B -8473
RGS21 -8474
RHOC -8537
CDK5 -8579
RXFP2 -8604
ACKR2 -8611
ANXA1 -8615
GLP1R -8618
GNA13 -8637
FPR2 -8660
CCL11 -8682
PDYN -8793
GHRHR -8817
GNG8 -8827
CCKAR -8831
CRHBP -8854
FPR1 -8873
CCL1 -8874
TAS2R10 -8970
ADCYAP1 -8983
CYSLTR2 -9048
ARHGEF39 -9064
CCL25 -9160
TACR1 -9199
RLN2 -9230
RGS5 -9398
MC1R -9422
HRH4 -9445
TAS2R43 -9495
TAS2R9 -9502
GALR1 -9521
TAS2R4 -9605
FZD4 -9616
CXCL6 -9625
S1PR4 -9628
TAS2R39 -9707
TAC3 -9751
CCL13 -9850
PDE1A -9872
SHC1 -9953
CCL7 -9960
AGT -9987
PROKR2 -10023
NPS -10041
MC5R -10080
GNRHR -10220
FFAR3 -10297
MMP3 -10298
KEL -10427
NPFFR2 -10429
LHB -10541
MCHR1 -10571
RXFP4 -10604
CCL3 -10623
TAS2R41 -10734
MTNR1B -10795
GPRC6A -10893
UTS2 -11033


REACTOME_SARS_COV_1_HOST_INTERACTIONS

REACTOME_SARS_COV_1_HOST_INTERACTIONS
1550
set REACTOME_SARS_COV_1_HOST_INTERACTIONS
setSize 92
pANOVA 6.08e-05
s.dist -0.242
p.adjustANOVA 0.00624



Top enriched genes

Top 20 genes
GeneID Gene Rank
STING1 -11042
SFTPD -10550
BST2 -10425
RPS6 -10417
NFKBIA -10413
TBK1 -10313
RPSA -9995
RPS2 -9929
RPS13 -9755
CASP1 -9494
TOMM70 -9371
PPIH -9010
PSMC6 -8596
YWHAE -8482
NMI -8379
HNRNPA1 -8376
RPS8 -8297
IRF3 -8235
RPS11 -8218
KPNB1 -8106

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
STING1 -11042
SFTPD -10550
BST2 -10425
RPS6 -10417
NFKBIA -10413
TBK1 -10313
RPSA -9995
RPS2 -9929
RPS13 -9755
CASP1 -9494
TOMM70 -9371
PPIH -9010
PSMC6 -8596
YWHAE -8482
NMI -8379
HNRNPA1 -8376
RPS8 -8297
IRF3 -8235
RPS11 -8218
KPNB1 -8106
PKLR -7858
RIGI -7847
IFIH1 -7381
KPNA2 -7242
RPS18 -7152
CAV1 -6823
PPIA -6821
UBA52 -6801
RPS20 -6503
RPS26 -6380
FAU -6321
UBC -6316
RPS7 -6226
RPS27L -5336
RPS27A -5186
FKBP1A -5100
RPS16 -5010
EP300 -4854
TRAF6 -4779
YWHAG -4529
RPS5 -4476
RPS25 -4396
EEF1A1 -4286
SERPINE1 -4233
RIPK3 -4070
NLRP3 -4066
YWHAZ -4048
NPM1 -3970
TRIM25 -3912
RPS21 -3340
RELA -3044
ITCH -3021
PPIG -2506
RPS19 -2325
RPS29 -2223
RPS9 -1875
RPS12 -1300
BCL2L1 -1138
YWHAH -1106
SMAD4 -536
RUNX1 243
YWHAQ 560
RPS15A 633
SIKE1 842
RPS28 847
PCBP2 1054
NFKB1 1146
RPS23 1371
RPS10 1817
RPS27 1846
RPS3 2010
SFN 2141
RPS14 2461
PALS1 2521
YWHAB 2669
RPS24 2982
PPIB 3075
RPS15 3636
MAVS 3718
UBB 4462
IRAK2 4637
SP1 4737
PYCARD 5085
RCAN3 5403
RPS3A 5749
TKFC 5858
UBE2I 5866
SMAD3 7074
TRAF3 7256
RIPK1 9142
PDPK1 9459
IKBKE 9564


REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY

REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY
635
set REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY
setSize 64
pANOVA 0.000112
s.dist 0.279
p.adjustANOVA 0.0105



Top enriched genes

Top 20 genes
GeneID Gene Rank
CD3D 10807
PDCD1 10731
CD247 10653
LCK 10594
CTLA4 10525
CSK 10156
PDPK1 9459
PIK3R1 8263
CD80 8236
RAC1 8122
CD28 8118
GRAP2 8091
SRC 8026
AKT2 7901
CD3G 7876
CD4 7785
BTLA 7778
TRIB3 7514
PRR5 7473
AKT3 7414

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CD3D 10807
PDCD1 10731
CD247 10653
LCK 10594
CTLA4 10525
CSK 10156
PDPK1 9459
PIK3R1 8263
CD80 8236
RAC1 8122
CD28 8118
GRAP2 8091
SRC 8026
AKT2 7901
CD3G 7876
CD4 7785
BTLA 7778
TRIB3 7514
PRR5 7473
AKT3 7414
AKT1 7231
PPP2R1B 7101
CD3E 6838
LYN 6800
MAP3K14 6794
PAK2 6728
PPP2CB 6598
MLST8 6512
HLA-DQB2 6491
MTOR 6428
PTPN6 6359
CDC42 6139
PIK3R2 5878
MAPKAP1 5820
HLA-DRA 5373
HLA-DRB1 5202
FYN 4117
PPP2R5A 3918
PPP2R5C 3911
PDCD1LG2 2486
HLA-DQA2 2200
PPP2R5E 784
PPP2R5B 439
GRB2 152
HLA-DRB5 -758
HLA-DQB1 -903
PTPN11 -957
HLA-DQA1 -1038
VAV1 -2494
PAK1 -2523
PIK3R3 -3645
YES1 -4284
PPP2R1A -5096
PIK3CA -5583
PPP2R5D -5910
CD274 -6069
RICTOR -6156
THEM4 -6288
PPP2CA -7146
HLA-DPB1 -7874
MAP3K8 -8129
CD86 -9525
HLA-DPA1 -10385
ICOS -10617


REACTOME_SARS_COV_2_HOST_INTERACTIONS

REACTOME_SARS_COV_2_HOST_INTERACTIONS
1571
set REACTOME_SARS_COV_2_HOST_INTERACTIONS
setSize 191
pANOVA 0.000115
s.dist -0.162
p.adjustANOVA 0.0105



Top enriched genes

Top 20 genes
GeneID Gene Rank
STING1 -11042
IFNA21 -10838
IFNA7 -10834
IFNA1 -10778
SFTPD -10550
RPS6 -10417
TBK1 -10313
IFNA14 -10046
RPSA -9995
ISG15 -9963
RPS2 -9929
RPS13 -9755
SNRPE -9711
CRB3 -9637
SNRPG -9530
MBL2 -9497
GEMIN6 -9483
TOMM70 -9371
NOD1 -9366
POM121 -9356

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
STING1 -11042.0
IFNA21 -10838.0
IFNA7 -10834.0
IFNA1 -10778.0
SFTPD -10550.0
RPS6 -10417.0
TBK1 -10313.0
IFNA14 -10046.0
RPSA -9995.0
ISG15 -9963.0
RPS2 -9929.0
RPS13 -9755.0
SNRPE -9711.0
CRB3 -9637.0
SNRPG -9530.0
MBL2 -9497.0
GEMIN6 -9483.0
TOMM70 -9371.0
NOD1 -9366.0
POM121 -9356.0
HLA-B -9281.0
IFNA2 -9041.0
TRIM4 -8892.0
IL17RC -8886.0
POM121C -8815.0
SNRPD3 -8507.0
YWHAE -8482.0
RIPK2 -8395.0
SEH1L -8298.0
RPS8 -8297.0
IRF3 -8235.0
RPS11 -8218.0
DDX20 -8080.0
TLR1 -8018.0
RIGI -7847.0
IFNA8 -7791.0
NUP155 -7766.0
MAP1LC3B -7759.0
G3BP1 -7554.0
GEMIN2 -7420.0
HLA-G -7383.0
IFIH1 -7381.0
HLA-C -7307.0
KPNA2 -7242.0
RPS18 -7152.0
HLA-F -7024.0
NUP58 -6850.0
CAV1 -6823.0
UBA52 -6801.0
NUP54 -6598.0
VPS33A -6521.0
RPS20 -6503.0
IL17RA -6493.0
NLRP12 -6466.0
RPS26 -6380.0
FAU -6321.0
UBC -6316.0
RPS7 -6226.0
SEC13 -5971.0
NUP43 -5857.0
ATG14 -5821.0
HSP90AA1 -5799.0
SNRPF -5670.0
NUP37 -5559.0
HLA-E -5353.0
RPS27L -5336.0
RPS27A -5186.0
VPS39 -5122.0
RPS16 -5010.0
NUP153 -4963.0
TRAF6 -4779.0
SNRPB -4640.0
YWHAG -4529.0
RPS5 -4476.0
B2M -4432.0
IFNA16 -4428.0
RPS25 -4396.0
UBE2N -4353.0
NDC1 -4338.0
GEMIN5 -4166.0
NLRP3 -4066.0
YWHAZ -4048.0
TRIM25 -3912.0
VPS11 -3911.0
GEMIN7 -3503.0
HLA-A -3407.0
RPS21 -3340.0
TPR -3264.0
SEC24A -3048.0
IFNA13 -2934.0
MASP2 -2717.0
IRF7 -2637.0
VPS18 -2609.0
PIK3C3 -2548.0
RANBP2 -2371.0
RPS19 -2325.0
RPS29 -2223.0
BECN1 -2149.0
RPS9 -1875.0
NUP98 -1787.0
VPS33B -1715.0
NUP42 -1540.0
SEC24D -1529.0
STAT2 -1485.0
RPS12 -1300.0
YWHAH -1106.0
CHUK -1089.0
PATJ -987.0
SAR1B -975.0
PTPN11 -957.0
TJP1 -925.0
G3BP2 -369.0
TAB2 -340.0
NUP214 -322.0
SNRPD2 -175.0
UVRAG -122.0
MAP3K7 -66.0
NUP88 31.0
TUFM 548.0
YWHAQ 560.0
RPS15A 633.0
NUP160 766.0
SIKE1 842.0
RPS28 847.0
SEC24B 908.0
TLR2 959.0
NUP50 1298.0
RPS23 1371.0
VPS45 1406.0
GJA1 1691.0
RPS10 1817.0
NUP107 1840.0
SMN1 1844.5
SMN2 1844.5
RPS27 1846.0
STAT1 1869.0
RPS3 2010.0
HSP90AB1 2011.0
GEMIN4 2093.0
SFN 2141.0
VPS16 2296.0
NOD2 2401.0
NUP85 2441.0
RPS14 2461.0
PALS1 2521.0
YWHAB 2669.0
TYK2 2850.0
IFNA5 2890.0
RPS24 2982.0
PIK3R4 3173.0
NUP205 3348.0
NUP62 3360.0
IFNAR1 3464.0
RPS15 3636.0
LARP1 3688.0
MAVS 3718.0
NUP93 3792.0
NUP133 4054.0
VPS41 4251.0
IL17F 4307.0
UBB 4462.0
IRAK2 4637.0
IKBKB 4646.0
RNF135 5479.0
SEC23A 5634.0
AAAS 5713.0
IFNAR2 5737.0
RPS3A 5749.0
RAE1 5767.0
CNBP 5774.0
NUP188 5843.0
UBE2V1 5855.0
TKFC 5858.0
PTPN6 6359.0
NUP35 6436.0
AKT1 7231.0
TRAF3 7256.0
CREBBP 7316.0
AKT3 7414.0
SNRPD1 7715.0
SEC24C 7896.0
AKT2 7901.0
MASP1 8286.0
NUP210 9050.0
IL17A 9164.0
PDPK1 9459.0
IKBKE 9564.0
TAB1 9714.0
JAK1 9739.0
IFNA6 9955.0
IFNB1 10578.0


REACTOME_CELL_CYCLE_MITOTIC

REACTOME_CELL_CYCLE_MITOTIC
1112
set REACTOME_CELL_CYCLE_MITOTIC
setSize 539
pANOVA 0.000135
s.dist -0.0961
p.adjustANOVA 0.0116



Top enriched genes

Top 20 genes
GeneID Gene Rank
SKA1 -10474
HAUS5 -10433
CKS1B -10321
TUBAL3 -10277
CCNE2 -10221
MZT2B -9951
RBL1 -9915
H4C1 -9861
ZWINT -9760
PSMB8 -9663
CDC45 -9610
CDK6 -9599
H2AC14 -9573
ANAPC15 -9537
CENPH -9492
TUBA1B -9443
CENPM -9403
H3C10 -9400
POM121 -9356
SPC24 -9314

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SKA1 -10474.0
HAUS5 -10433.0
CKS1B -10321.0
TUBAL3 -10277.0
CCNE2 -10221.0
MZT2B -9951.0
RBL1 -9915.0
H4C1 -9861.0
ZWINT -9760.0
PSMB8 -9663.0
CDC45 -9610.0
CDK6 -9599.0
H2AC14 -9573.0
ANAPC15 -9537.0
CENPH -9492.0
TUBA1B -9443.0
CENPM -9403.0
H3C10 -9400.0
POM121 -9356.0
SPC24 -9314.0
LIN9 -9289.0
ENSA -9257.0
PSMB9 -9156.0
CDC23 -9096.0
NEK9 -9068.0
H3C4 -9046.0
ESCO1 -8989.0
TUBG1 -8922.0
SGO2 -8914.0
NUF2 -8895.0
PSMB6 -8884.0
MZT2A -8829.0
DCTN2 -8826.0
POM121C -8815.0
SPAST -8804.0
PSMB11 -8782.0
HMMR -8760.0
PPME1 -8695.0
CCND2 -8675.0
HAUS3 -8612.0
AURKA -8606.0
PSMC6 -8596.0
BUB3 -8515.0
TUBB4A -8498.0
CENPE -8497.0
LCMT1 -8495.0
YWHAE -8482.0
XPO1 -8435.0
SPC25 -8412.0
CDK7 -8404.0
TMPO -8403.0
NME7 -8400.0
WEE1 -8318.0
B9D2 -8304.0
SEH1L -8298.0
PHLDA1 -8260.0
RAB1A -8250.0
CDKN1B -8228.0
TUBA3E -8172.0
MCM5 -8148.0
CENPC -8131.0
KPNB1 -8106.0
CEP135 -7947.0
NEK2 -7927.0
PSMB4 -7922.0
ALMS1 -7909.0
TUBGCP6 -7888.0
MAD2L1 -7849.0
NUP155 -7766.0
SMC4 -7720.0
ANAPC1 -7673.0
LMNB1 -7667.0
DNA2 -7655.0
PSMD12 -7515.0
CENPJ -7429.0
CEP70 -7388.0
CDKN2B -7379.0
CDK4 -7365.0
CHMP2B -7362.0
TUBB3 -7345.0
PSMD9 -7320.0
OPTN -7311.0
MYBL2 -7253.0
PSMD14 -7231.0
E2F5 -7183.0
FOXM1 -7178.0
PPP2CA -7146.0
TYMS -7133.0
ORC3 -7128.0
ZWILCH -7094.0
CHMP4C -7073.0
RB1 -7068.0
TK1 -7019.0
CDKN1C -7013.0
CENPA -6977.0
CDK11A -6968.0
H3-3A -6960.0
CEP152 -6935.0
NUP58 -6850.0
UBA52 -6801.0
DBF4 -6772.0
PMF1 -6759.0
ANAPC11 -6670.0
NUP54 -6598.0
PSMD4 -6582.0
VRK2 -6563.0
H3C2 -6560.0
ORC2 -6518.0
MCM8 -6418.0
FBXO5 -6404.0
NCAPH2 -6359.0
TUBB2A -6353.0
DSN1 -6320.0
UBC -6316.0
CSNK2B -6285.0
MAPRE1 -6261.0
TNPO1 -6249.0
NCAPG2 -6221.0
ORC6 -6213.0
PDS5A -6168.0
CDC25A -6142.0
MCM2 -6125.0
CEP43 -6123.0
KIF23 -6115.0
HAUS2 -6106.0
LIG1 -6088.0
TUBA4B -5985.0
SEC13 -5971.0
USO1 -5943.0
MIS12 -5938.0
SKP2 -5922.0
PPP2R5D -5910.0
DYNLL1 -5861.0
NUP43 -5857.0
NCAPD3 -5824.0
LIN37 -5823.0
PSMD5 -5814.0
H2BC1 -5805.0
HSP90AA1 -5799.0
PTK6 -5748.0
CCNA2 -5676.0
PSME1 -5657.0
TAOK1 -5648.0
NUP37 -5559.0
LEMD3 -5529.0
PSMA2 -5475.0
PRIM1 -5463.0
MCM10 -5362.0
MCM6 -5361.0
SEM1 -5318.0
RBBP4 -5281.0
H2BC15 -5237.0
POLD2 -5218.0
RPS27A -5186.0
CENPK -5180.0
ACTR1A -5178.0
CDKN2C -5168.0
CCNA1 -5158.0
H2AC7 -5146.5
H2BC7 -5146.5
PPP2R1A -5096.0
BLZF1 -5092.0
MCPH1 -5081.0
DHFR -4990.0
NUP153 -4963.0
KIF2B -4931.0
TUBB -4906.0
KIF2C -4885.0
EP300 -4854.0
PSMA6 -4797.0
TPX2 -4780.0
CDC14A -4754.0
SMC3 -4742.0
KIF18A -4735.0
LIN54 -4721.0
H4C13 -4659.0
RAB8A -4654.0
PSMB10 -4647.0
CEP63 -4637.0
H3C11 -4615.0
H3C1 -4612.0
SET -4564.0
H2AX -4544.0
YWHAG -4529.0
H4C4 -4490.0
ODF2 -4447.0
NDC1 -4338.0
CDC20 -4306.0
NSL1 -4256.0
CSNK1E -4241.0
CDKN1A -4217.0
IST1 -4108.0
BANF1 -4097.0
LIN52 -4088.0
GMNN -4026.0
H2AZ2 -4022.0
GTSE1 -3959.0
H2AC4 -3882.0
CENPN -3878.0
SMC2 -3848.0
RFC3 -3831.0
PSMC5 -3766.0
ESCO2 -3756.0
CTDNEP1 -3672.0
AURKB -3669.0
E2F2 -3649.0
PSMC3 -3596.0
H2BC5 -3590.0
SGO1 -3585.0
SSNA1 -3514.0
CCNH -3426.0
NCAPD2 -3411.0
E2F6 -3359.0
JAK2 -3310.0
CDC7 -3293.0
E2F4 -3276.0
MCM4 -3266.0
TPR -3264.0
CUL1 -3240.0
H2BC13 -3197.0
H3C12 -3194.0
H4C3 -3175.0
ORC1 -3151.0
H2AC18 -3116.5
H2AC19 -3116.5
MNAT1 -3025.0
PSMB1 -2993.0
FBXL7 -2986.0
FEN1 -2985.0
AHCTF1 -2974.0
CENPO -2968.0
HAUS4 -2951.0
CDCA5 -2895.0
PLK1 -2865.0
CDC27 -2821.0
ANAPC10 -2801.0
RPA2 -2757.0
PSMD8 -2756.0
H2BC10 -2688.0
PSMB7 -2674.0
H4C5 -2560.0
CDK2 -2539.0
KNL1 -2515.0
CKAP5 -2464.0
PSMD7 -2423.0
CABLES1 -2415.0
H2BC21 -2387.0
RANBP2 -2371.0
TUBB8 -2320.0
H4C8 -2282.0
MYC -2245.0
H3C8 -2242.0
POLD4 -2233.0
ANKLE2 -2232.0
HAUS1 -2197.0
NUDC -2181.0
NCAPG -2171.0
SKP1 -2150.0
DYNC1I2 -2130.0
MAX -2102.0
LPIN1 -2095.0
CENPS -2075.0
RAB1B -2022.0
CDK5RAP2 -1975.0
TUBG2 -1962.0
CNEP1R1 -1865.0
H2BC14 -1854.0
UBE2E1 -1821.0
NUP98 -1787.0
PCNA -1764.0
PSME4 -1747.0
SUMO1 -1732.0
CDK1 -1714.0
ANAPC4 -1598.0
NDE1 -1553.0
UBE2S -1552.0
NUP42 -1540.0
PLK4 -1533.0
CCNB1 -1461.0
E2F1 -1457.0
H2AZ1 -1407.0
KNTC1 -1394.0
PCM1 -1375.0
ZW10 -1259.0
CEP72 -1114.0
PKMYT1 -1059.0
RAB2A -1057.0
POLD3 -1021.0
SKA2 -1002.0
CHMP3 -961.0
BUB1 -901.0
H2AC6 -857.0
RAD21 -752.0
BIRC5 -702.0
CCNB2 -677.0
CCND1 -635.0
RFC2 -610.0
CDC25C -492.0
DCTN1 -415.0
NIPBL -390.0
H3C6 -336.0
NDC80 -332.0
CENPF -326.0
NUP214 -322.0
POLD1 -286.0
POLE2 -265.0
GORASP2 -218.0
PSME3 -213.0
PRKAR2B -205.0
GINS4 -144.0
CDKN2A -111.0
PPP1R12A -109.0
WAPL -80.0
KIF20A -44.0
ORC4 -19.0
NUP88 31.0
GSK3B 35.0
CHMP2A 55.0
H2BC6 90.0
PSMA8 102.0
RFC4 130.0
GINS2 148.0
PSMB2 204.0
ITGB3BP 228.0
NINL 316.0
PSMD3 413.0
PPP2R5B 439.0
MCM7 455.0
BUB1B 508.0
PSMC1 563.0
LBR 652.0
H4C6 711.0
TUBB4B 746.0
NUP160 766.0
PSMC2 780.0
PPP2R5E 784.0
DYNC1H1 846.0
ANAPC7 997.0
VPS4A 1032.0
PDS5B 1088.0
UBE2C 1092.0
CLASP1 1107.0
H2AC20 1183.0
TUBA4A 1191.0
H2BC8 1285.0
NUP50 1298.0
RBL2 1302.0
TFDP2 1340.0
SIRT2 1409.0
CCP110 1430.0
H4C2 1432.0
DYNC1LI1 1464.0
CEP290 1515.0
PSME2 1567.0
POLA2 1629.0
H4C16 1648.0
PSMF1 1681.0
PSMA4 1711.0
CHMP4B 1816.0
ESPL1 1820.0
NUP107 1840.0
RPS27 1846.0
CENPU 1878.0
PCNT 1913.0
NEDD1 1927.0
PRKCB 1981.0
PSMB5 1998.0
HSP90AB1 2011.0
H2BC11 2126.0
TOP2A 2147.0
CENPT 2225.0
ANAPC16 2248.0
PSMA7 2284.0
FZR1 2319.0
CDC16 2338.0
CENPL 2376.0
H3-4 2378.0
NUP85 2441.0
CCNE1 2460.0
UBE2D1 2470.0
CENPP 2484.0
SFI1 2592.0
ANAPC5 2686.0
BORA 2698.0
CENPQ 2705.0
PSMD11 2717.0
RFC5 2789.0
DCTN3 2794.0
PRKACA 2802.0
PPP1CB 2817.0
EML4 2825.0
FBXL18 2839.0
FBXW11 2843.0
CEP192 2876.0
H2BC12 2999.0
CEP57 3006.0
MZT1 3011.0
CEP131 3094.0
ORC5 3123.0
CEP76 3284.0
RCC1 3329.0
NUP205 3348.0
DYNC1I1 3356.0
NUP62 3360.0
CDCA8 3384.0
H2AC8 3419.0
CHMP7 3421.0
PRKCA 3441.0
H2BC26 3442.0
INCENP 3471.0
PSMA3 3474.0
ANAPC2 3537.0
CNTRL 3603.0
AJUBA 3702.0
MAPK3 3720.0
RPA3 3737.0
PPP1R12B 3790.0
NUP93 3792.0
H3-3B 3816.0
PTTG1 3869.0
ARPP19 3872.0
CEP164 3882.0
PSMD1 3904.0
PPP2R5C 3911.0
PPP2R5A 3918.0
TUBA1A 4010.0
CDC26 4020.0
NUP133 4054.0
CLIP1 4115.0
DYNC1LI2 4150.0
SDCCAG8 4152.0
E2F3 4178.0
CSNK2A2 4246.0
TUBGCP5 4255.0
CCND3 4326.0
H2BC17 4334.0
CEP41 4373.0
MAPK1 4404.0
UBB 4462.0
KMT5A 4476.0
LMNA 4553.0
CDC25B 4567.0
CDT1 4619.0
MASTL 4677.0
PPP2R2A 4746.0
ABL1 4846.0
TUBA1C 4895.0
GINS1 5007.0
VRK1 5093.0
TUBB2B 5110.0
NCAPH 5127.0
AKAP9 5154.0
MAU2 5164.0
HDAC1 5175.0
BTRC 5196.0
PPP2R2D 5277.0
TP53 5315.0
STAG1 5334.0
NUMA1 5471.0
POLE 5476.0
CEP78 5567.0
H2BC4 5571.0
RFC1 5672.0
AAAS 5713.0
GOLGA2 5725.0
GORASP1 5731.0
PPP1CC 5761.0
RAE1 5767.0
HAUS8 5778.0
NEK7 5796.0
PSMD2 5837.0
NUP188 5843.0
H4C9 5861.0
H4C12 5863.0
UBE2I 5866.0
FKBPL 5920.0
RBX1 6251.0
NUP35 6436.0
MAD1L1 6595.0
PPP2CB 6598.0
PSMA5 6687.0
POLE4 6691.0
H2BC3 6745.0
TUBA8 6777.0
LYN 6800.0
RPA1 6866.0
HAUS6 6969.0
NDEL1 7021.0
SPDL1 7032.0
PPP2R1B 7101.0
TUBGCP3 7154.0
AKT1 7231.0
PAFAH1B1 7265.0
TUBGCP4 7355.0
DYRK1A 7403.0
AKT3 7414.0
PSMC4 7451.0
RAN 7477.0
TUBGCP2 7508.0
PSMD6 7550.0
PSMA1 7633.0
TUBB1 7829.0
CEP250 7862.0
AKT2 7901.0
NEK6 7983.0
CDK11B 8012.0
SRC 8026.0
MCM3 8167.0
RANGAP1 8224.0
H2AJ 8230.0
TFDP1 8331.0
RCC2 8360.0
CHMP6 8376.0
PSMD13 8449.0
PRIM2 8529.0
LEMD2 8596.0
RRM2 8620.0
CLASP2 8727.0
TUBB6 8755.0
PSMB3 8759.0
GINS3 8840.0
CSNK1D 8903.0
CDC6 8920.0
H3C3 8927.0
H2BC9 8981.5
H3C7 8981.5
LPIN2 9000.0
POLE3 9009.0
NUP210 9050.0
LPIN3 9081.0
CC2D1B 9124.0
CDKN2D 9223.0
CHMP4A 9314.0
CSNK2A1 9563.0
TUBA3C 9921.0
KIF2A 9935.0
H4C11 10159.0
DYNLL2 10336.0
TUBA3D 10642.0


REACTOME_CELL_CYCLE

REACTOME_CELL_CYCLE
190
set REACTOME_CELL_CYCLE
setSize 666
pANOVA 0.000169
s.dist -0.0855
p.adjustANOVA 0.0138



Top enriched genes

Top 20 genes
GeneID Gene Rank
NOP10 -10749
SKA1 -10474
HAUS5 -10433
CKS1B -10321
RAD51C -10289
TUBAL3 -10277
CCNE2 -10221
POLR2H -9976
MZT2B -9951
RBL1 -9915
H4C1 -9861
ZWINT -9760
POLR2K -9746
RBBP8 -9701
PSMB8 -9663
GAR1 -9619
CDC45 -9610
CDK6 -9599
H2AC14 -9573
ANAPC15 -9537

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NOP10 -10749.0
SKA1 -10474.0
HAUS5 -10433.0
CKS1B -10321.0
RAD51C -10289.0
TUBAL3 -10277.0
CCNE2 -10221.0
POLR2H -9976.0
MZT2B -9951.0
RBL1 -9915.0
H4C1 -9861.0
ZWINT -9760.0
POLR2K -9746.0
RBBP8 -9701.0
PSMB8 -9663.0
GAR1 -9619.0
CDC45 -9610.0
CDK6 -9599.0
H2AC14 -9573.0
ANAPC15 -9537.0
CENPH -9492.0
TUBA1B -9443.0
PRDM9 -9420.0
CENPM -9403.0
H3C10 -9400.0
POM121 -9356.0
SPC24 -9314.0
LIN9 -9289.0
ENSA -9257.0
DSCC1 -9220.0
MLH1 -9203.0
PSMB9 -9156.0
CDC23 -9096.0
NEK9 -9068.0
H3C4 -9046.0
ESCO1 -8989.0
TUBG1 -8922.0
SGO2 -8914.0
NUF2 -8895.0
PSMB6 -8884.0
MZT2A -8829.0
DCTN2 -8826.0
POM121C -8815.0
SPAST -8804.0
PSMB11 -8782.0
HMMR -8760.0
ANKRD28 -8711.0
PPME1 -8695.0
CCND2 -8675.0
HAUS3 -8612.0
AURKA -8606.0
PSMC6 -8596.0
BUB3 -8515.0
TUBB4A -8498.0
CENPE -8497.0
LCMT1 -8495.0
YWHAE -8482.0
XPO1 -8435.0
SPC25 -8412.0
CDK7 -8404.0
TMPO -8403.0
NME7 -8400.0
WEE1 -8318.0
B9D2 -8304.0
SEH1L -8298.0
TINF2 -8291.0
PHLDA1 -8260.0
RAB1A -8250.0
CDKN1B -8228.0
TUBA3E -8172.0
MCM5 -8148.0
RAD1 -8135.0
CENPC -8131.0
KPNB1 -8106.0
TEN1 -7953.0
CEP135 -7947.0
NEK2 -7927.0
PSMB4 -7922.0
ALMS1 -7909.0
TUBGCP6 -7888.0
MAD2L1 -7849.0
NUP155 -7766.0
SMC4 -7720.0
MIS18A -7688.0
ANAPC1 -7673.0
LMNB1 -7667.0
DNA2 -7655.0
RHNO1 -7548.0
PSMD12 -7515.0
CENPJ -7429.0
RAD51 -7408.0
CEP70 -7388.0
CDKN2B -7379.0
CDK4 -7365.0
CHMP2B -7362.0
TUBB3 -7345.0
MLH3 -7337.0
PSMD9 -7320.0
OPTN -7311.0
EXO1 -7294.0
MYBL2 -7253.0
PSMD14 -7231.0
E2F5 -7183.0
FOXM1 -7178.0
ACD -7166.5
SYNE2 -7161.0
PPP2CA -7146.0
MSH4 -7145.0
TYMS -7133.0
ORC3 -7128.0
ZWILCH -7094.0
CHMP4C -7073.0
RB1 -7068.0
TK1 -7019.0
CDKN1C -7013.0
CHEK2 -7011.0
CENPA -6977.0
CDK11A -6968.0
H3-3A -6960.0
CEP152 -6935.0
NUP58 -6850.0
TP53BP1 -6839.0
UBA52 -6801.0
DBF4 -6772.0
PMF1 -6759.0
HJURP -6747.0
ANAPC11 -6670.0
BRCA2 -6661.0
NUP54 -6598.0
PSMD4 -6582.0
VRK2 -6563.0
H3C2 -6560.0
ORC2 -6518.0
PCBP4 -6477.0
MCM8 -6418.0
FBXO5 -6404.0
NCAPH2 -6359.0
TUBB2A -6353.0
DSN1 -6320.0
UBC -6316.0
RAD17 -6301.0
CSNK2B -6285.0
MAPRE1 -6261.0
TNPO1 -6249.0
NCAPG2 -6221.0
ORC6 -6213.0
PDS5A -6168.0
HSPA2 -6148.0
CDC25A -6142.0
CHTF8 -6127.0
MCM2 -6125.0
CEP43 -6123.0
SYCE1 -6122.0
KIF23 -6115.0
HAUS2 -6106.0
LIG1 -6088.0
TUBA4B -5985.0
SEC13 -5971.0
USO1 -5943.0
MIS12 -5938.0
SKP2 -5922.0
CLSPN -5918.0
PPP2R5D -5910.0
DYNLL1 -5861.0
NUP43 -5857.0
NCAPD3 -5824.0
LIN37 -5823.0
PSMD5 -5814.0
H2BC1 -5805.0
HSP90AA1 -5799.0
NHP2 -5749.0
PTK6 -5748.0
CCNA2 -5676.0
PSME1 -5657.0
TAOK1 -5648.0
NUP37 -5559.0
LEMD3 -5529.0
PSMA2 -5475.0
PRIM1 -5463.0
MCM10 -5362.0
MCM6 -5361.0
SEM1 -5318.0
RBBP4 -5281.0
H2BC15 -5237.0
POLD2 -5218.0
RPS27A -5186.0
CENPK -5180.0
ACTR1A -5178.0
CDKN2C -5168.0
CCNA1 -5158.0
H2AC7 -5146.5
H2BC7 -5146.5
PPP2R1A -5096.0
BLZF1 -5092.0
MCPH1 -5081.0
DHFR -4990.0
NUP153 -4963.0
KIF2B -4931.0
TUBB -4906.0
KIF2C -4885.0
BLM -4880.0
MND1 -4855.0
EP300 -4854.0
POLR2I -4813.0
PSMA6 -4797.0
TPX2 -4780.0
CDC14A -4754.0
SMC3 -4742.0
KIF18A -4735.0
LIN54 -4721.0
H4C13 -4659.0
RAB8A -4654.0
PSMB10 -4647.0
CEP63 -4637.0
H3C11 -4615.0
H3C1 -4612.0
SET -4564.0
RAD9B -4553.0
RAD50 -4547.0
H2AX -4544.0
YWHAG -4529.0
H4C4 -4490.0
ODF2 -4447.0
UBE2N -4353.0
NDC1 -4338.0
CDC20 -4306.0
NSL1 -4256.0
CSNK1E -4241.0
CDKN1A -4217.0
MDC1 -4185.0
DMC1 -4131.0
IST1 -4108.0
BANF1 -4097.0
LIN52 -4088.0
YWHAZ -4048.0
GMNN -4026.0
H2AZ2 -4022.0
NPM1 -3970.0
GTSE1 -3959.0
H2AC4 -3882.0
CENPN -3878.0
SMC2 -3848.0
RFC3 -3831.0
PSMC5 -3766.0
ESCO2 -3756.0
CTDNEP1 -3672.0
AURKB -3669.0
E2F2 -3649.0
PSMC3 -3596.0
H2BC5 -3590.0
SGO1 -3585.0
SSNA1 -3514.0
CCNH -3426.0
MSH5 -3412.0
NCAPD2 -3411.0
E2F6 -3359.0
JAK2 -3310.0
CDC7 -3293.0
E2F4 -3276.0
POLR2D -3271.0
MCM4 -3266.0
TPR -3264.0
CUL1 -3240.0
H2BC13 -3197.0
H3C12 -3194.0
H4C3 -3175.0
ORC1 -3151.0
H2AC18 -3116.5
H2AC19 -3116.5
MRE11 -3107.0
FKBP6 -3069.0
MNAT1 -3025.0
PSMB1 -2993.0
TERT -2988.0
FBXL7 -2986.0
FEN1 -2985.0
AHCTF1 -2974.0
CENPO -2968.0
HAUS4 -2951.0
CDCA5 -2895.0
PLK1 -2865.0
KAT5 -2846.0
CDC27 -2821.0
ANAPC10 -2801.0
RPA2 -2757.0
PSMD8 -2756.0
H2BC10 -2688.0
PSMB7 -2674.0
H4C5 -2560.0
CDK2 -2539.0
KNL1 -2515.0
CKAP5 -2464.0
PSMD7 -2423.0
CABLES1 -2415.0
TERF1 -2399.0
H2BC21 -2387.0
RANBP2 -2371.0
ATR -2361.0
TUBB8 -2320.0
H4C8 -2282.0
MYC -2245.0
H3C8 -2242.0
POLD4 -2233.0
ANKLE2 -2232.0
HAUS1 -2197.0
NUDC -2181.0
NCAPG -2171.0
SKP1 -2150.0
DYNC1I2 -2130.0
MAX -2102.0
LPIN1 -2095.0
CENPS -2075.0
RAB1B -2022.0
CDK5RAP2 -1975.0
TUBG2 -1962.0
CNEP1R1 -1865.0
H2BC14 -1854.0
UBE2E1 -1821.0
NUP98 -1787.0
PCNA -1764.0
PSME4 -1747.0
SUMO1 -1732.0
CDK1 -1714.0
PPP6R3 -1638.0
ANAPC4 -1598.0
ATM -1566.0
NDE1 -1553.0
UBE2S -1552.0
NUP42 -1540.0
PLK4 -1533.0
PIF1 -1470.0
CCNB1 -1461.0
E2F1 -1457.0
H2AZ1 -1407.0
KNTC1 -1394.0
PCM1 -1375.0
ZW10 -1259.0
RNF168 -1197.0
SMARCA5 -1191.0
CEP72 -1114.0
YWHAH -1106.0
PKMYT1 -1059.0
RAB2A -1057.0
POLD3 -1021.0
SKA2 -1002.0
CHMP3 -961.0
RMI1 -904.0
BUB1 -901.0
H2AC6 -857.0
TEX15 -818.0
RAD21 -752.0
BIRC5 -702.0
CCNB2 -677.0
CCND1 -635.0
RFC2 -610.0
POLR2A -529.0
CDC25C -492.0
DCTN1 -415.0
SYCP1 -402.0
NIPBL -390.0
H3C6 -336.0
NDC80 -332.0
CENPF -326.0
NUP214 -322.0
POLD1 -286.0
POLE2 -265.0
POLR2E -232.0
GORASP2 -218.0
PSME3 -213.0
PRKAR2B -205.0
GINS4 -144.0
TERF2IP -138.0
CDKN2A -111.0
PPP1R12A -109.0
WAPL -80.0
KIF20A -44.0
ORC4 -19.0
RSF1 -5.0
NUP88 31.0
GSK3B 35.0
CHMP2A 55.0
BRCA1 68.0
H2BC6 90.0
PSMA8 102.0
DAXX 115.0
RFC4 130.0
RUVBL2 134.0
GINS2 148.0
PSMB2 204.0
RNF8 209.0
ITGB3BP 228.0
NINL 316.0
SHQ1 393.0
PSMD3 413.0
POLR2G 414.0
PPP2R5B 439.0
PSMC3IP 442.0
MCM7 455.0
SYCE2 496.0
BUB1B 508.0
YWHAQ 560.0
PSMC1 563.0
TERF2 577.0
ABRAXAS1 636.0
LBR 652.0
H4C6 711.0
TUBB4B 746.0
NUP160 766.0
PSMC2 780.0
PPP2R5E 784.0
DYNC1H1 846.0
ANAPC7 997.0
VPS4A 1032.0
PDS5B 1088.0
UBE2C 1092.0
SUN2 1094.0
CLASP1 1107.0
H2AC20 1183.0
TUBA4A 1191.0
POLR2C 1205.0
H2BC8 1285.0
NUP50 1298.0
RBL2 1302.0
TOP3A 1315.0
TFDP2 1340.0
SIRT2 1409.0
CCP110 1430.0
H4C2 1432.0
DYNC1LI1 1464.0
COP1 1479.0
CEP290 1515.0
PSME2 1567.0
POLA2 1629.0
H4C16 1648.0
PSMF1 1681.0
PHF20 1695.0
PSMA4 1711.0
CHMP4B 1816.0
ESPL1 1820.0
NUP107 1840.0
RPS27 1846.0
CENPU 1878.0
PCNT 1913.0
NEDD1 1927.0
PRKCB 1981.0
PSMB5 1998.0
HSP90AB1 2011.0
H2BC11 2126.0
SFN 2141.0
NSD2 2146.0
TOP2A 2147.0
CENPW 2183.0
CENPT 2225.0
ANAPC16 2248.0
PSMA7 2284.0
FZR1 2319.0
CDC16 2338.0
OIP5 2368.0
CENPL 2376.0
H3-4 2378.0
MIS18BP1 2424.0
NUP85 2441.0
CCNE1 2460.0
UBE2D1 2470.0
CENPP 2484.0
SFI1 2592.0
YWHAB 2669.0
ANAPC5 2686.0
BORA 2698.0
CENPQ 2705.0
PSMD11 2717.0
RFC5 2789.0
DCTN3 2794.0
PRKACA 2802.0
PPP1CB 2817.0
EML4 2825.0
FBXL18 2839.0
FBXW11 2843.0
CEP192 2876.0
SYNE1 2967.0
H2BC12 2999.0
CEP57 3006.0
MZT1 3011.0
CEP131 3094.0
RMI2 3099.0
ORC5 3123.0
BABAM1 3254.0
CEP76 3284.0
RCC1 3329.0
SUN1 3333.0
NUP205 3348.0
DYNC1I1 3356.0
NUP62 3360.0
CDCA8 3384.0
H2AC8 3419.0
CHMP7 3421.0
PRKCA 3441.0
H2BC26 3442.0
INCENP 3471.0
PSMA3 3474.0
POLR2F 3481.0
TOPBP1 3532.0
ANAPC2 3537.0
CNTRL 3603.0
SYCE3 3694.0
AJUBA 3702.0
MAPK3 3720.0
RPA3 3737.0
PPP1R12B 3790.0
NUP93 3792.0
H3-3B 3816.0
BARD1 3826.0
SYCP3 3863.0
PTTG1 3869.0
ARPP19 3872.0
CEP164 3882.0
PSMD1 3904.0
PPP2R5C 3911.0
PPP2R5A 3918.0
TUBA1A 4010.0
CDC26 4020.0
RUVBL1 4050.0
NUP133 4054.0
CLIP1 4115.0
DYNC1LI2 4150.0
BABAM2 4151.0
SDCCAG8 4152.0
E2F3 4178.0
HERC2 4232.0
SPO11 4235.0
CSNK2A2 4246.0
TUBGCP5 4255.0
CCND3 4326.0
H2BC17 4334.0
CEP41 4373.0
SMC1B 4387.0
MAPK1 4404.0
UBB 4462.0
KMT5A 4476.0
LMNA 4553.0
CDC25B 4567.0
CHTF18 4574.0
CDT1 4619.0
SYCP2 4623.0
MASTL 4677.0
PPP2R2A 4746.0
HUS1 4791.0
WRN 4809.0
ABL1 4846.0
TUBA1C 4895.0
CHEK1 4963.0
GINS1 5007.0
VRK1 5093.0
TUBB2B 5110.0
NCAPH 5127.0
MDM4 5136.0
AKAP9 5154.0
MAU2 5164.0
HDAC1 5175.0
BTRC 5196.0
PPP2R2D 5277.0
NBN 5285.0
TP53 5315.0
STAG1 5334.0
STN1 5445.0
NUMA1 5471.0
POLE 5476.0
RTEL1 5484.0
CEP78 5567.0
H2BC4 5571.0
ATRIP 5649.0
UBE2V2 5662.0
RFC1 5672.0
AAAS 5713.0
BRIP1 5714.0
GOLGA2 5725.0
GORASP1 5731.0
PPP1CC 5761.0
RAE1 5767.0
HAUS8 5778.0
NEK7 5796.0
PSMD2 5837.0
NUP188 5843.0
MDM2 5847.0
H4C9 5861.0
H4C12 5863.0
UBE2I 5866.0
FKBPL 5920.0
RBX1 6251.0
POT1 6352.0
TEX12 6412.0
NUP35 6436.0
MAD1L1 6595.0
PPP2CB 6598.0
PSMA5 6687.0
POLE4 6691.0
H2BC3 6745.0
TUBA8 6777.0
LYN 6800.0
RPA1 6866.0
STAG3 6867.0
HAUS6 6969.0
NDEL1 7021.0
SPDL1 7032.0
PPP2R1B 7101.0
POLR2B 7108.0
TUBGCP3 7154.0
AKT1 7231.0
PAFAH1B1 7265.0
TUBGCP4 7355.0
DYRK1A 7403.0
AKT3 7414.0
PSMC4 7451.0
RAN 7477.0
TUBGCP2 7508.0
PSMD6 7550.0
PSMA1 7633.0
CTC1 7728.0
TUBB1 7829.0
CEP250 7862.0
AKT2 7901.0
RAD9A 7910.0
WRAP53 7945.0
NEK6 7983.0
CDK11B 8012.0
SRC 8026.0
UIMC1 8042.0
REC8 8108.0
MCM3 8167.0
RANGAP1 8224.0
H2AJ 8230.0
TFDP1 8331.0
RCC2 8360.0
CHMP6 8376.0
PSMD13 8449.0
POLR2L 8498.0
PRIM2 8529.0
LEMD2 8596.0
RRM2 8620.0
DIDO1 8680.0
CLASP2 8727.0
TUBB6 8755.0
PSMB3 8759.0
GINS3 8840.0
CSNK1D 8903.0
CDC6 8920.0
H3C3 8927.0
H2BC9 8981.5
H3C7 8981.5
LPIN2 9000.0
POLE3 9009.0
NUP210 9050.0
PPP6C 9075.0
LPIN3 9081.0
PIAS4 9089.0
CC2D1B 9124.0
CDKN2D 9223.0
ZNF385A 9303.0
CHMP4A 9314.0
CSNK2A1 9563.0
TUBA3C 9921.0
KIF2A 9935.0
H4C11 10159.0
DYNLL2 10336.0
POLR2J 10513.0
TUBA3D 10642.0


REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S

REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S
1150
set REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S
setSize 53
pANOVA 0.00018
s.dist -0.297
p.adjustANOVA 0.0141



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS6 -10417
RPSA -9995
RPS2 -9929
EIF4A2 -9888
RPS13 -9755
EIF3A -9731
EIF2S1 -9084
EIF3M -8950
EIF3K -8754
RPS8 -8297
RPS11 -8218
RPS18 -7152
EIF3G -7070
RPS20 -6503
EIF2S2 -6426
EIF3L -6407
RPS26 -6380
FAU -6321
RPS7 -6226
EIF4H -5691

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS6 -10417
RPSA -9995
RPS2 -9929
EIF4A2 -9888
RPS13 -9755
EIF3A -9731
EIF2S1 -9084
EIF3M -8950
EIF3K -8754
RPS8 -8297
RPS11 -8218
RPS18 -7152
EIF3G -7070
RPS20 -6503
EIF2S2 -6426
EIF3L -6407
RPS26 -6380
FAU -6321
RPS7 -6226
EIF4H -5691
RPS27L -5336
RPS27A -5186
RPS16 -5010
EIF4EBP1 -4579
RPS5 -4476
RPS25 -4396
EIF3I -3533
EIF4A1 -3505
RPS21 -3340
EIF3F -2457
RPS19 -2325
RPS29 -2223
EIF4G1 -2048
RPS9 -1875
EIF3D -1554
EIF4B -1318
RPS12 -1300
PABPC1 575
RPS15A 633
EIF3E 663
RPS28 847
EIF3H 858
EIF3J 1346
RPS23 1371
EIF4E 1594
RPS10 1817
RPS27 1846
RPS3 2010
RPS14 2461
RPS24 2982
RPS15 3636
RPS3A 5749
EIF3B 9606


REACTOME_SARS_COV_2_MODULATES_HOST_TRANSLATION_MACHINERY

REACTOME_SARS_COV_2_MODULATES_HOST_TRANSLATION_MACHINERY
1601
set REACTOME_SARS_COV_2_MODULATES_HOST_TRANSLATION_MACHINERY
setSize 46
pANOVA 0.000327
s.dist -0.306
p.adjustANOVA 0.0242



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS6 -10417
RPSA -9995
RPS2 -9929
RPS13 -9755
SNRPE -9711
SNRPG -9530
GEMIN6 -9483
SNRPD3 -8507
RPS8 -8297
RPS11 -8218
DDX20 -8080
GEMIN2 -7420
RPS18 -7152
RPS20 -6503
RPS26 -6380
FAU -6321
RPS7 -6226
SNRPF -5670
RPS27L -5336
RPS27A -5186

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS6 -10417.0
RPSA -9995.0
RPS2 -9929.0
RPS13 -9755.0
SNRPE -9711.0
SNRPG -9530.0
GEMIN6 -9483.0
SNRPD3 -8507.0
RPS8 -8297.0
RPS11 -8218.0
DDX20 -8080.0
GEMIN2 -7420.0
RPS18 -7152.0
RPS20 -6503.0
RPS26 -6380.0
FAU -6321.0
RPS7 -6226.0
SNRPF -5670.0
RPS27L -5336.0
RPS27A -5186.0
RPS16 -5010.0
SNRPB -4640.0
RPS5 -4476.0
RPS25 -4396.0
GEMIN5 -4166.0
GEMIN7 -3503.0
RPS21 -3340.0
RPS19 -2325.0
RPS29 -2223.0
RPS9 -1875.0
RPS12 -1300.0
SNRPD2 -175.0
RPS15A 633.0
RPS28 847.0
RPS23 1371.0
RPS10 1817.0
SMN1 1844.5
SMN2 1844.5
RPS27 1846.0
RPS3 2010.0
GEMIN4 2093.0
RPS14 2461.0
RPS24 2982.0
RPS15 3636.0
RPS3A 5749.0
SNRPD1 7715.0


REACTOME_THE_ROLE_OF_NEF_IN_HIV_1_REPLICATION_AND_DISEASE_PATHOGENESIS

REACTOME_THE_ROLE_OF_NEF_IN_HIV_1_REPLICATION_AND_DISEASE_PATHOGENESIS
197
set REACTOME_THE_ROLE_OF_NEF_IN_HIV_1_REPLICATION_AND_DISEASE_PATHOGENESIS
setSize 27
pANOVA 0.000339
s.dist 0.398
p.adjustANOVA 0.0242



Top enriched genes

Top 20 genes
GeneID Gene Rank
CD247 10653
LCK 10594
AP1B1 9032
AP1M1 8678
RAC1 8122
CD28 8118
CD8B 8086
AP1M2 8006
CD4 7785
PACS1 6964
AP1S3 6744
PAK2 6728
AP1S1 6175
AP2A2 5798
DOCK2 5516
ARF1 5126
AP1G1 4903
FYN 4117
AP2M1 3974
ELMO1 1971

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CD247 10653
LCK 10594
AP1B1 9032
AP1M1 8678
RAC1 8122
CD28 8118
CD8B 8086
AP1M2 8006
CD4 7785
PACS1 6964
AP1S3 6744
PAK2 6728
AP1S1 6175
AP2A2 5798
DOCK2 5516
ARF1 5126
AP1G1 4903
FYN 4117
AP2M1 3974
ELMO1 1971
AP2B1 755
ATP6V1H 752
AP2A1 -2362
HLA-A -3407
AP2S1 -4124
B2M -4432
HCK -8426


REACTOME_RAB_GEFS_EXCHANGE_GTP_FOR_GDP_ON_RABS

REACTOME_RAB_GEFS_EXCHANGE_GTP_FOR_GDP_ON_RABS
1265
set REACTOME_RAB_GEFS_EXCHANGE_GTP_FOR_GDP_ON_RABS
setSize 81
pANOVA 0.000377
s.dist 0.229
p.adjustANOVA 0.0258



Top enriched genes

Top 20 genes
GeneID Gene Rank
RINL 10645
DENND2D 10238
RIN3 9601
RAB12 9256
TRAPPC10 9244
ALS2CL 9207
HPS1 9190
TRAPPC5 9013
CHML 9011
SBF1 8783
RAB6A 8722
DENND5A 8719
TRAPPC2L 8610
RAB38 8322
RIN1 8141
AKT2 7901
RIN2 7679
HPS4 7584
DENND4B 7484
AKT3 7414

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RINL 10645
DENND2D 10238
RIN3 9601
RAB12 9256
TRAPPC10 9244
ALS2CL 9207
HPS1 9190
TRAPPC5 9013
CHML 9011
SBF1 8783
RAB6A 8722
DENND5A 8719
TRAPPC2L 8610
RAB38 8322
RIN1 8141
AKT2 7901
RIN2 7679
HPS4 7584
DENND4B 7484
AKT3 7414
DENND1C 7401
DENND6A 7233
AKT1 7231
DENND4A 6855
RAB3GAP1 6846
TRAPPC8 5952
DENND1A 5795
MADD 5538
TRAPPC9 5533
TRAPPC12 5493
GAPVD1 5291
RAB21 5289
TRAPPC11 5088
RAB3A 4842
DENND3 4834
RAB3IP 4590
RAB27A 4340
RAB35 3825
RAB6B 3456
DENND6B 3420
RAB3GAP2 3235
TRAPPC6B 2872
DENND2B 2822
RAB31 2805
SBF2 2178
DENND2A 2022
TRAPPC13 1934
ULK1 1674
RAB5B 1442
RAB7A 1190
DENND1B 701
DENND5B 399
GDI2 335
RAB32 98
DENND2C 74
MON1B -771
RAB5A -1468
TRAPPC4 -1637
RGP1 -1853
RAB3IL1 -1967
RAB1B -2022
RABGEF1 -2068
RIC1 -2112
RAB8B -2136
RAB13 -2227
RAB14 -2510
TRAPPC3 -2879
RAB5C -3986
DENND4C -4192
ALS2 -4210
RAB27B -4508
RAB8A -4654
ANKRD27 -5046
RAB18 -5905
MON1A -6303
RAB39A -6304
RAB10 -6771
RAB1A -8250
YWHAE -8482
TRAPPC6A -9032
TRAPPC1 -10309


REACTOME_SIGNALING_BY_NODAL

REACTOME_SIGNALING_BY_NODAL
52
set REACTOME_SIGNALING_BY_NODAL
setSize 20
pANOVA 0.000667
s.dist 0.439
p.adjustANOVA 0.0438



Top enriched genes

Top 20 genes
GeneID Gene Rank
NODAL 10431
DAND5 10408
LEFTY1 9541
GDF1 9083
DRAP1 9049
ACVR1B 7661
SMAD2 7427
SMAD3 7074
FURIN 6735
FOXH1 6156
MAPK1 4404
ACVR1C 4261
ACVR2A 4182
MAPK3 3720
FOXO3 3479
ACVR2B 2946
LEFTY2 372
SMAD4 -536
PCSK6 -1210
CER1 -10317

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NODAL 10431
DAND5 10408
LEFTY1 9541
GDF1 9083
DRAP1 9049
ACVR1B 7661
SMAD2 7427
SMAD3 7074
FURIN 6735
FOXH1 6156
MAPK1 4404
ACVR1C 4261
ACVR2A 4182
MAPK3 3720
FOXO3 3479
ACVR2B 2946
LEFTY2 372
SMAD4 -536
PCSK6 -1210
CER1 -10317


REACTOME_CDC42_GTPASE_CYCLE

REACTOME_CDC42_GTPASE_CYCLE
1371
set REACTOME_CDC42_GTPASE_CYCLE
setSize 144
pANOVA 0.000714
s.dist 0.163
p.adjustANOVA 0.0451



Top enriched genes

Top 20 genes
GeneID Gene Rank
ARHGEF5 10564
ARAP3 10534
ARHGAP9 10444
FGD3 9990
ARHGDIA 9595
PREX1 9399
PLEKHG3 9378
WIPF2 9345
ARHGAP45 9175
FMNL3 9022
ARHGEF16 8962
ARHGEF25 8637
PLEKHG1 8497
DEF6 8490
PIK3R1 8263
TAGAP 8114
ARHGEF4 8030
ARHGDIG 7743
TRIO 7734
MYO9B 7729

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ARHGEF5 10564.0
ARAP3 10534.0
ARHGAP9 10444.0
FGD3 9990.0
ARHGDIA 9595.0
PREX1 9399.0
PLEKHG3 9378.0
WIPF2 9345.0
ARHGAP45 9175.0
FMNL3 9022.0
ARHGEF16 8962.0
ARHGEF25 8637.0
PLEKHG1 8497.0
DEF6 8490.0
PIK3R1 8263.0
TAGAP 8114.0
ARHGEF4 8030.0
ARHGDIG 7743.0
TRIO 7734.0
MYO9B 7729.0
KCTD3 7522.0
PLEKHG2 7423.0
BAIAP2 7360.0
ARHGAP1 7325.0
ARFGAP2 6876.0
PAK2 6728.0
LAMTOR1 6683.0
VAV2 6650.0
CDC42BPB 6616.0
PAK6 6482.0
ARHGAP29 6274.0
CDC42 6139.0
SCRIB 6030.0
DOCK8 5975.0
DOCK10 5883.0
PIK3R2 5878.0
CDC42EP4 5792.0
FNBP1L 5675.0
ARHGAP27 5610.0
ARAP1 5425.0
DIAPH3 5410.0
CDC42EP2 5396.0
ARHGAP17 5355.0
CDC42EP3 5319.0
WDR91 5293.0
ECT2 5168.0
ARAP2 5162.0
BCR 5105.0
ARHGEF7 5050.0
ARHGAP35 5006.0
ABR 4989.0
ARHGDIB 4552.0
ARHGEF11 4551.0
SYDE1 4495.0
GIT1 4166.0
YKT6 4146.0
SH3PXD2A 4097.0
CDC42EP1 3895.0
IQGAP2 3894.0
STEAP3 3812.0
ARHGEF10 3735.0
WDR81 3635.0
PAK5 3588.0
SPATA13 3488.0
FARP1 3461.0
ITSN1 3273.0
GIT2 3008.0
STARD13 2826.0
PLEKHG4 2648.0
ARHGAP26 2510.0
SRGAP2 2475.0
TIAM1 2402.0
ARFGAP3 2322.0
VANGL1 2301.0
ARHGAP30 2223.0
NGEF 2216.0
PLD1 1626.0
ARHGAP33 1454.0
ARHGAP10 1428.0
SRGAP3 1202.0
RAB7A 1190.0
DOCK7 983.0
SHKBP1 863.0
DAAM1 838.0
RASGRF2 804.0
FMNL2 767.0
PAK4 730.0
ARHGAP31 710.0
ARHGAP24 686.0
LBR 652.0
IQGAP1 580.0
WIPF1 416.0
WIPF3 113.0
ARHGEF15 39.0
ARHGAP21 -131.0
IQGAP3 -217.0
SNAP23 -766.0
VAV3 -820.0
SRGAP1 -859.0
ARHGAP32 -866.0
ARHGAP20 -1183.0
TFRC -1295.0
VAMP3 -1296.0
DEPDC1B -1325.0
ARHGEF26 -2193.0
DOCK6 -2287.0
DOCK9 -2439.0
PAK1 -2523.0
ARHGAP5 -2571.0
MAP3K11 -2699.0
ARHGEF12 -2842.0
STOM -2954.0
MCF2L -3089.0
FNBP1 -3364.0
ARHGAP22 -3544.0
RACGAP1 -3568.0
FGD4 -3623.0
CDC42EP5 -3692.0
PREX2 -3721.0
KTN1 -3843.0
FMNL1 -4036.0
CDC42SE2 -4151.0
CPNE8 -4171.0
DNMBP -4809.0
PLEKHG4B -4889.0
GMIP -4890.0
RALBP1 -5450.0
FGD2 -5484.0
CDC42BPA -5597.0
CHN1 -5649.0
WASL -6172.0
ARHGAP42 -6382.0
ARHGAP44 -6782.0
CAV1 -6823.0
PARD6A -7166.5
DLC1 -8278.0
TMPO -8403.0
ARHGEF19 -8415.0
ARHGAP39 -8479.0
ARHGAP40 -8486.0
GNA13 -8637.0
ARHGAP11B -9488.0
FAM13B -9516.0
JUP -9734.0


REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS

REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS
179
set REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS
setSize 111
pANOVA 0.000747
s.dist -0.185
p.adjustANOVA 0.0455



Top enriched genes

Top 20 genes
GeneID Gene Rank
COX8A -10815
SDHA -10483
NDUFAF3 -10350
COX18 -10300
COX5B -9985
SCO2 -9588
ATP5MC3 -9523
TMEM186 -9127
NDUFS1 -9044
NDUFB5 -9028
ETFDH -8766
NDUFB8 -8641
NDUFA3 -8602
UQCR11 -8558
UQCRC2 -8462
NDUFB4 -8185
NDUFV2 -7971
NDUFC1 -7819
ATP5F1B -7696
COX6A1 -7393

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
COX8A -10815
SDHA -10483
NDUFAF3 -10350
COX18 -10300
COX5B -9985
SCO2 -9588
ATP5MC3 -9523
TMEM186 -9127
NDUFS1 -9044
NDUFB5 -9028
ETFDH -8766
NDUFB8 -8641
NDUFA3 -8602
UQCR11 -8558
UQCRC2 -8462
NDUFB4 -8185
NDUFV2 -7971
NDUFC1 -7819
ATP5F1B -7696
COX6A1 -7393
NDUFS8 -7321
ATP5F1A -7219
NDUFA11 -7098
COX14 -6723
ATP5MF -6655
NDUFA12 -6608
UQCRB -6531
NDUFB7 -6423
SCO1 -6419
COX5A -6036
ATP5MG -5619
ATP5PO -5599
NDUFAF7 -5505
UQCRQ -5289
ATP5F1E -5262
NUBPL -5235
SDHD -5123
NDUFB3 -5000
NDUFA6 -4984
NDUFA2 -4957
NDUFS3 -4922
UQCR10 -4842
NDUFA5 -4819
ACAD9 -4309
NDUFB10 -4176
TMEM126B -3988
ATP5F1C -3976
SDHC -3941
NDUFA7 -3924
NDUFA9 -3811
COX20 -3695
PM20D1 -3536
COX11 -3323
NDUFAF5 -3294
LRPPRC -3178
ATP5PD -3128
NDUFV3 -3101
ATP5F1D -3073
COX6B1 -3060
ECSIT -2503
NDUFAB1 -2243
NDUFS5 -2206
COX4I1 -2088
UQCRFS1 -2060
TIMMDC1 -2015
ATP5MC1 -1625
ATP5MC2 -1416
NDUFC2 -1397
NDUFB1 -1354
NDUFB2 -1090
NDUFAF1 -954
TACO1 -812
ETFA -689
SLC25A27 -553
NDUFA10 -436
NDUFS4 -337
ATP5PF -104
UCP3 460
COX16 472
NDUFA4 514
COQ10B 747
COX6C 933
CYCS 1030
NDUFB6 1066
SURF1 1316
CYC1 1972
TRAP1 2114
UQCRH 2316
SDHB 3093
COX7A2L 3493
NDUFB9 3621
NDUFV1 3967
ATP5PB 4341
UQCRC1 4765
NDUFAF2 4987
NDUFS7 5039
COX7C 5354
NDUFS6 5587
UCP2 5818
UCP1 6555
COX19 6890
COQ10A 7361
NDUFA8 7432
NDUFAF6 7567
ATP5ME 7987
NDUFA13 8527
NDUFS2 8750
NDUFAF4 8938
DMAC2L 9116
COA1 9264
ETFB 9681


REACTOME_SIGNALING_BY_ROBO_RECEPTORS

REACTOME_SIGNALING_BY_ROBO_RECEPTORS
605
set REACTOME_SIGNALING_BY_ROBO_RECEPTORS
setSize 206
pANOVA 0.000789
s.dist -0.136
p.adjustANOVA 0.0463



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL10L -10791.0
RPS6 -10417.0
RPL10A -10270.0
RPSA -9995.0
RPL15 -9935.0
RPS2 -9929.0
RPL36AL -9900.5
RPL3 -9806.0
RPS13 -9755.0
RPL23 -9683.0
PSMB8 -9663.0
RPL4 -9310.0
RPL22L1 -9170.0
PSMB9 -9156.0
RPL23A -9136.0
RPL18A -9066.0
RBM8A -8942.0
PSMB6 -8884.0
PSMB11 -8782.0
PSMC6 -8596.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL10L -10791.0
RPS6 -10417.0
RPL10A -10270.0
RPSA -9995.0
RPL15 -9935.0
RPS2 -9929.0
RPL36AL -9900.5
RPL3 -9806.0
RPS13 -9755.0
RPL23 -9683.0
PSMB8 -9663.0
RPL4 -9310.0
RPL22L1 -9170.0
PSMB9 -9156.0
RPL23A -9136.0
RPL18A -9066.0
RBM8A -8942.0
PSMB6 -8884.0
PSMB11 -8782.0
PSMC6 -8596.0
RPL3L -8483.0
ARHGAP39 -8479.0
RPS8 -8297.0
RPL13 -8287.0
RPS11 -8218.0
RPLP1 -8007.0
MAGOHB -7942.0
PSMB4 -7922.0
RPL27 -7903.0
RPL26L1 -7810.0
PFN2 -7719.0
ROBO3 -7535.0
PSMD12 -7515.0
ETF1 -7512.0
RPL6 -7511.0
RPL29 -7474.0
PSMD9 -7320.0
NCK1 -7247.0
PSMD14 -7231.0
RPS18 -7152.0
CASC3 -6807.0
UBA52 -6801.0
CAP2 -6717.0
PSMD4 -6582.0
RPS20 -6503.0
SLIT2 -6396.0
RPS26 -6380.0
FAU -6321.0
UBC -6316.0
RPL13A -6274.5
RPS7 -6226.0
RPL26 -6001.0
RHOA -5826.0
PSMD5 -5814.0
CUL2 -5781.0
PSME1 -5657.0
LHX2 -5609.0
ROBO2 -5579.0
RPL39L -5553.0
RPL12 -5545.0
EIF4A3 -5476.0
PSMA2 -5475.0
ROBO1 -5471.0
RPL8 -5420.0
RPS27L -5336.0
SEM1 -5318.0
RPLP0 -5288.0
LHX9 -5228.0
RPS27A -5186.0
RPS16 -5010.0
CAP1 -4918.0
PSMA6 -4797.0
PRKACB -4770.0
PSMB10 -4647.0
RPL5 -4568.0
RPS5 -4476.0
RPL32 -4474.0
RPS25 -4396.0
RPL28 -4371.0
NCBP1 -4260.0
PSMC5 -3766.0
RPL38 -3763.0
PFN1 -3702.0
PSMC3 -3596.0
ELOC -3352.0
CXCR4 -3351.0
RPS21 -3340.0
RPL24 -3320.0
VASP -3102.0
RPL35 -3005.0
PSMB1 -2993.0
PSMD8 -2756.0
RNPS1 -2753.0
PPP3CB -2745.0
PSMB7 -2674.0
DCC -2652.0
RPL21 -2532.0
PAK1 -2523.0
PSMD7 -2423.0
RPS19 -2325.0
HOXA2 -2284.0
RPS29 -2223.0
DAG1 -2199.0
EIF4G1 -2048.0
RPL37 -1881.0
RPS9 -1875.0
RPL22 -1859.0
RPL18 -1836.0
PSME4 -1747.0
NELL2 -1534.0
RPL17 -1516.0
RPS12 -1300.0
ABL2 -1151.0
SOS1 -1066.0
RPL7 -1014.0
PRKACG -999.0
SRGAP1 -859.0
NRP1 -665.0
UPF2 -618.0
PRKAR2A -455.0
MSI1 -383.0
PSME3 -213.0
SOS2 73.0
PSMA8 102.0
PSMB2 204.0
NTN1 275.0
RPL27A 317.0
PSMD3 413.0
PSMC1 563.0
PABPC1 575.0
RPS15A 633.0
PAK4 730.0
PSMC2 780.0
RPS28 847.0
CLASP1 1107.0
RPL41 1186.0
SRGAP3 1202.0
RPS23 1371.0
PSME2 1567.0
PSMF1 1681.0
FLRT3 1704.0
PSMA4 1711.0
RPS10 1817.0
RPS27 1846.0
SLIT3 1850.0
PSMB5 1998.0
RPS3 2010.0
UPF3A 2101.0
LHX4 2259.0
PSMA7 2284.0
RPLP2 2399.0
RPL7A 2419.0
RPL37A 2421.0
RPS14 2461.0
SRGAP2 2475.0
PSMD11 2717.0
PRKACA 2802.0
RPS24 2982.0
RPL11 3088.0
NCK2 3285.0
RPL31 3319.0
PRKCA 3441.0
PSMA3 3474.0
PAK5 3588.0
RPL9 3600.0
RPS15 3636.0
RPL34 3769.0
RPL30 3899.0
PSMD1 3904.0
RPL36 4049.0
NCBP2 4072.0
USP33 4305.0
UBB 4462.0
LDB1 4490.0
RPL14 4501.0
RPL19 4703.0
RPL35A 4845.0
ABL1 4846.0
ISL1 5362.0
ENAH 5366.0
ELOB 5389.0
RPS3A 5749.0
PSMD2 5837.0
GSPT1 5984.0
CDC42 6139.0
RBX1 6251.0
PAK6 6482.0
GPC1 6657.0
PSMA5 6687.0
PAK2 6728.0
CXCL12 6779.0
MAGOH 7040.0
AKAP5 7179.0
PSMC4 7451.0
PSMD6 7550.0
PSMA1 7633.0
MYO9B 7729.0
SRC 8026.0
RAC1 8122.0
SLIT1 8142.0
LHX3 8326.0
PSMD13 8449.0
CLASP2 8727.0
PSMB3 8759.0
EVL 9997.0
ZSWIM8 10297.0


REACTOME_SYNTHESIS_OF_LIPOXINS_LX

REACTOME_SYNTHESIS_OF_LIPOXINS_LX
448
set REACTOME_SYNTHESIS_OF_LIPOXINS_LX
setSize 6
pANOVA 0.000825
s.dist 0.788
p.adjustANOVA 0.0467



Top enriched genes

Top 20 genes
GeneID Gene Rank
ALOX12 10545
ALOX5AP 10038
LTC4S 9618
HPGD 8788
ALOX5 8355
PTGR1 4157

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ALOX12 10545
ALOX5AP 10038
LTC4S 9618
HPGD 8788
ALOX5 8355
PTGR1 4157


REACTOME_PHOSPHOLIPID_METABOLISM

REACTOME_PHOSPHOLIPID_METABOLISM
136
set REACTOME_PHOSPHOLIPID_METABOLISM
setSize 201
pANOVA 0.000855
s.dist 0.136
p.adjustANOVA 0.0468



Top enriched genes

Top 20 genes
GeneID Gene Rank
PISD 10665
PIK3C2A 10437
PLA2G4B 10069
DGAT1 10048
VAC14 9914
GPD2 9809
SYNJ2 9743
CSNK2A1 9563
GDPD3 9554
PEMT 9525
PTDSS2 9485
INPP4A 9238
PLA1A 9158
PIK3R6 9156
LPIN3 9081
LPIN2 9000
PLD6 8983
SBF1 8783
PLB1 8656
CHKA 8471

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PISD 10665
PIK3C2A 10437
PLA2G4B 10069
DGAT1 10048
VAC14 9914
GPD2 9809
SYNJ2 9743
CSNK2A1 9563
GDPD3 9554
PEMT 9525
PTDSS2 9485
INPP4A 9238
PLA1A 9158
PIK3R6 9156
LPIN3 9081
LPIN2 9000
PLD6 8983
SBF1 8783
PLB1 8656
CHKA 8471
STARD10 8357
AGPAT3 8320
PIK3R1 8263
PLA2G4D 8059
GPAT4 7990
PITPNM3 7984
GPD1 7977
INPP5D 7921
PLEKHA3 7892
AGPAT4 7827
PLEKHA5 7768
GPD1L 7586
MTMR10 7554
PIK3R5 7450
ENPP6 7430
PIP4K2A 7367
MBOAT7 7222
GDPD5 7210
OSBPL5 7187
PCTP 7014
TNFAIP8L1 6751
PLD4 6718
PI4K2B 6696
LCLAT1 6649
PLBD1 6635
PLEKHA2 6563
DGAT2 6539
CEPT1 6538
TPTE2 6457
CDS2 6445
ABHD4 6306
PIP5K1C 6285
PLA2G15 6134
INPP4B 6104
MTMR2 6086
CRLS1 6062
PNPLA6 5997
PIK3R2 5878
PTDSS1 5862
INPPL1 5833
MGLL 5816
PLAAT2 5788
LPCAT1 5735
PLA2G3 5481
CDIPT 5447
LPCAT2 5420
GPAM 5418
SLC44A4 5398
PIK3C2B 5259
ARF1 5126
TNFAIP8L3 5055
AGPAT1 4891
MIGA1 4855
MTMR3 4614
PLA2G2F 4572
LPCAT3 4471
PITPNM1 4430
PCYT1A 4315
CSNK2A2 4246
PIK3CD 4140
CPNE7 4027
PIP5K1A 3784
CPNE6 3608
CDS1 3555
LPCAT4 3394
DDHD1 3344
MTMR9 3243
PIK3R4 3173
PLEKHA8 3069
PLA2G4A 3000
PTPN13 2979
INPP5F 2863
MTMR12 2741
PLA2G1B 2733
PIP5K1B 2613
PLD2 2363
PI4KA 2194
SBF2 2178
MFSD2A 1942
LIPI 1858
ETNPPL 1822
ABHD3 1713
PLD1 1626
CHKB 1536
RUFY1 1463
ACP6 1404
PIP4K2B 1352
PLD3 1279
PLAAT4 1259
MBOAT2 1221
PLA2G4F 1176
PLEKHA6 1134
GDPD1 1079
PLA2G6 1025
PIK3CB 975
MTMR14 869
SLC44A2 865
PI4KB 849
LIPH 800
PLA2G4C 696
PITPNM2 612
PLA2R1 451
ARF3 398
PLAAT1 331
ACHE 291
MTMR4 212
AGPAT2 122
PNPLA3 100
PIP4K2C -100
ALPI -335
INPP5J -407
CHAT -663
ETNK1 -693
TMEM86B -781
GPCPD1 -867
ETNK2 -875
PLAAT3 -1195
PNPLA2 -1360
OSBPL10 -1464
RAB5A -1468
AGPAT5 -1581
TNFAIP8 -1794
LPIN1 -2095
PNPLA8 -2475
RAB14 -2510
PIK3C3 -2548
MTMR7 -2568
STARD7 -2602
AGK -2714
SYNJ1 -2772
PIK3CG -2882
SLC44A1 -3177
INPP5K -3236
PIK3R3 -3645
PI4K2A -3648
SLC44A3 -3733
GNPAT -3876
INPP5E -4031
PTEN -4334
PNPLA7 -4651
PLAAT5 -4664
FIG4 -5086
CHPT1 -5118
SACM1L -5359
MBOAT1 -5530
PIK3CA -5583
PLEKHA1 -5584
LPGAT1 -5710
PGS1 -5872
PLA2G4E -5904
PCYT2 -6234
CSNK2B -6285
RAB4A -6339
SLC44A5 -6361
MTMR6 -6547
PITPNB -6550
PIK3C2G -6613
DDHD2 -6851
MIGA2 -6887
OSBPL8 -6957
PLA2G5 -7445
TNFAIP8L2 -7625
PLA2G12A -7666
PLA2G2D -7770
CPNE1 -7787
GDE1 -8035
PHOSPHO1 -8071
PIKFYVE -8182
PLEKHA4 -8197
HADHA -8471
TPTE -8493
SELENOI -8567
HADHB -8898
PLA2G2A -9287
PTPMT1 -9446
BCHE -9471
PIP4P1 -9597
PLA2G2E -9688
GPAT2 -9984
CPNE3 -10447
PLA2G10 -10583


REACTOME_RESPIRATORY_ELECTRON_TRANSPORT

REACTOME_RESPIRATORY_ELECTRON_TRANSPORT
1026
set REACTOME_RESPIRATORY_ELECTRON_TRANSPORT
setSize 90
pANOVA 0.0011
s.dist -0.199
p.adjustANOVA 0.0561



Top enriched genes

Top 20 genes
GeneID Gene Rank
COX8A -10815
SDHA -10483
NDUFAF3 -10350
COX18 -10300
COX5B -9985
SCO2 -9588
TMEM186 -9127
NDUFS1 -9044
NDUFB5 -9028
ETFDH -8766
NDUFB8 -8641
NDUFA3 -8602
UQCR11 -8558
UQCRC2 -8462
NDUFB4 -8185
NDUFV2 -7971
NDUFC1 -7819
COX6A1 -7393
NDUFS8 -7321
NDUFA11 -7098

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
COX8A -10815
SDHA -10483
NDUFAF3 -10350
COX18 -10300
COX5B -9985
SCO2 -9588
TMEM186 -9127
NDUFS1 -9044
NDUFB5 -9028
ETFDH -8766
NDUFB8 -8641
NDUFA3 -8602
UQCR11 -8558
UQCRC2 -8462
NDUFB4 -8185
NDUFV2 -7971
NDUFC1 -7819
COX6A1 -7393
NDUFS8 -7321
NDUFA11 -7098
COX14 -6723
NDUFA12 -6608
UQCRB -6531
NDUFB7 -6423
SCO1 -6419
COX5A -6036
NDUFAF7 -5505
UQCRQ -5289
NUBPL -5235
SDHD -5123
NDUFB3 -5000
NDUFA6 -4984
NDUFA2 -4957
NDUFS3 -4922
UQCR10 -4842
NDUFA5 -4819
ACAD9 -4309
NDUFB10 -4176
TMEM126B -3988
SDHC -3941
NDUFA7 -3924
NDUFA9 -3811
COX20 -3695
COX11 -3323
NDUFAF5 -3294
LRPPRC -3178
NDUFV3 -3101
COX6B1 -3060
ECSIT -2503
NDUFAB1 -2243
NDUFS5 -2206
COX4I1 -2088
UQCRFS1 -2060
TIMMDC1 -2015
NDUFC2 -1397
NDUFB1 -1354
NDUFB2 -1090
NDUFAF1 -954
TACO1 -812
ETFA -689
NDUFA10 -436
NDUFS4 -337
COX16 472
NDUFA4 514
COQ10B 747
COX6C 933
CYCS 1030
NDUFB6 1066
SURF1 1316
CYC1 1972
TRAP1 2114
UQCRH 2316
SDHB 3093
COX7A2L 3493
NDUFB9 3621
NDUFV1 3967
UQCRC1 4765
NDUFAF2 4987
NDUFS7 5039
COX7C 5354
NDUFS6 5587
COX19 6890
COQ10A 7361
NDUFA8 7432
NDUFAF6 7567
NDUFA13 8527
NDUFS2 8750
NDUFAF4 8938
COA1 9264
ETFB 9681


REACTOME_ELASTIC_FIBRE_FORMATION

REACTOME_ELASTIC_FIBRE_FORMATION
148
set REACTOME_ELASTIC_FIBRE_FORMATION
setSize 44
pANOVA 0.00113
s.dist 0.284
p.adjustANOVA 0.0561



Top enriched genes

Top 20 genes
GeneID Gene Rank
LOXL4 10559
FBN3 8885
FBN2 8556
BMP4 8336
ITGB6 8051
EFEMP2 7999
MFAP5 7160
TGFB3 6943
FURIN 6735
LTBP3 6525
ITGA5 6432
ITGB5 6269
FBLN2 6265
MFAP4 6031
EFEMP1 5879
FBLN1 5707
LOXL2 5663
MFAP2 5658
TGFB2 5394
EMILIN1 5388

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
LOXL4 10559
FBN3 8885
FBN2 8556
BMP4 8336
ITGB6 8051
EFEMP2 7999
MFAP5 7160
TGFB3 6943
FURIN 6735
LTBP3 6525
ITGA5 6432
ITGB5 6269
FBLN2 6265
MFAP4 6031
EFEMP1 5879
FBLN1 5707
LOXL2 5663
MFAP2 5658
TGFB2 5394
EMILIN1 5388
VTN 4650
ITGB8 4314
BMP7 3830
FBLN5 2910
ITGAV 2311
ITGB1 2034
LOXL3 1747
EMILIN2 1708
LOX 1466
MFAP3 1293
TGFB1 1028
LTBP1 1009
LTBP2 749
ITGB3 470
EMILIN3 -405
FN1 -458
ITGA8 -1528
LOXL1 -1922
LTBP4 -3145
BMP10 -3762
FBN1 -4599
BMP2 -4966
ELN -5453
GDF5 -8506


REACTOME_RAC1_GTPASE_CYCLE

REACTOME_RAC1_GTPASE_CYCLE
1372
set REACTOME_RAC1_GTPASE_CYCLE
setSize 172
pANOVA 0.00113
s.dist 0.144
p.adjustANOVA 0.0561



Top enriched genes

Top 20 genes
GeneID Gene Rank
ARHGEF5 10564
ARAP3 10534
ARHGAP9 10444
ARHGDIA 9595
SWAP70 9545
PREX1 9399
PLEKHG3 9378
WIPF2 9345
NCF2 9191
ARHGAP45 9175
TIAM2 9123
PKN1 8915
ARHGEF25 8637
PLEKHG1 8497
DEF6 8490
MPP7 8346
MCAM 8290
PIK3R1 8263
RAC1 8122
TAGAP 8114

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ARHGEF5 10564.0
ARAP3 10534.0
ARHGAP9 10444.0
ARHGDIA 9595.0
SWAP70 9545.0
PREX1 9399.0
PLEKHG3 9378.0
WIPF2 9345.0
NCF2 9191.0
ARHGAP45 9175.0
TIAM2 9123.0
PKN1 8915.0
ARHGEF25 8637.0
PLEKHG1 8497.0
DEF6 8490.0
MPP7 8346.0
MCAM 8290.0
PIK3R1 8263.0
RAC1 8122.0
TAGAP 8114.0
ARHGEF4 8030.0
CYFIP2 7899.0
TRIO 7734.0
MYO9B 7729.0
PLEKHG2 7423.0
BAIAP2 7360.0
ARHGAP1 7325.0
PLEKHG6 7197.0
CYBA 7165.0
NCF4 7152.0
PAK2 6728.0
LAMTOR1 6683.0
VAV2 6650.0
PAK6 6482.0
ABI1 6400.0
ARHGAP29 6274.0
CDC42 6139.0
DOCK8 5975.0
DOCK10 5883.0
PIK3R2 5878.0
CDC42EP4 5792.0
ARHGAP27 5610.0
DOCK2 5516.0
AMIGO2 5495.0
ARAP1 5425.0
DIAPH3 5410.0
SH3BP1 5376.0
ARHGAP17 5355.0
ECT2 5168.0
ARAP2 5162.0
BCR 5105.0
ARHGEF7 5050.0
ARHGAP35 5006.0
ABR 4989.0
NISCH 4872.0
DOCK5 4718.0
GARRE1 4642.0
ARHGDIB 4552.0
ARHGEF11 4551.0
GIT1 4166.0
YKT6 4146.0
CDC42EP1 3895.0
IQGAP2 3894.0
ARHGEF10 3735.0
PAK5 3588.0
FARP2 3527.0
SPATA13 3488.0
FARP1 3461.0
ARHGEF18 3385.0
FERMT2 3266.0
WASF2 3132.0
GIT2 3008.0
DOCK3 3007.0
FAM13A 2997.0
PLEKHG4 2648.0
CHN2 2603.0
ARHGAP26 2510.0
SRGAP2 2475.0
ARHGAP12 2454.0
TIAM1 2402.0
PLD2 2363.0
VANGL1 2301.0
ARHGAP30 2223.0
NCKAP1 2220.0
NGEF 2216.0
ITGB1 2034.0
PLD1 1626.0
CIT 1504.0
ARHGAP33 1454.0
ARHGAP10 1428.0
ARHGAP15 1400.0
SRGAP3 1202.0
RAB7A 1190.0
DOCK4 1148.0
DOCK7 983.0
RASGRF2 804.0
PAK4 730.0
ARHGAP31 710.0
ARHGAP24 686.0
LBR 652.0
IQGAP1 580.0
DOCK1 571.0
WASF1 568.0
SYDE2 557.0
WIPF1 416.0
EPHA2 327.0
WIPF3 113.0
SOS2 73.0
ARHGEF15 39.0
ARHGAP21 -131.0
IQGAP3 -217.0
KALRN -313.0
TAOK3 -669.0
BAIAP2L1 -729.0
SNAP23 -766.0
VAV3 -820.0
SRGAP1 -859.0
ARHGAP32 -866.0
SOS1 -1066.0
ABL2 -1151.0
ARHGAP20 -1183.0
TFRC -1295.0
VAMP3 -1296.0
DEPDC1B -1325.0
ARHGAP23 -1331.0
JAG1 -1574.0
NOX3 -1616.0
NOXA1 -1765.0
ERBIN -1963.0
DOCK6 -2287.0
DOCK9 -2439.0
VAV1 -2494.0
PAK1 -2523.0
ARHGAP5 -2571.0
ABI2 -2936.0
MCF2L -3089.0
ARHGAP22 -3544.0
RACGAP1 -3568.0
PIK3R3 -3645.0
BRK1 -3653.0
PREX2 -3721.0
KTN1 -3843.0
FMNL1 -4036.0
ALS2 -4210.0
NCKAP1L -4346.0
GMIP -4890.0
WASF3 -4929.0
RALBP1 -5450.0
LEMD3 -5529.0
PIK3CA -5583.0
CDC42BPA -5597.0
CHN1 -5649.0
FGD5 -5797.0
PKN2 -6166.0
WASL -6172.0
ARHGAP42 -6382.0
VRK2 -6563.0
ARHGAP44 -6782.0
CAV1 -6823.0
PARD6A -7166.5
ARHGAP25 -7168.0
SLC1A5 -7239.0
CYFIP1 -7588.0
NOXO1 -8127.0
DLC1 -8278.0
TMPO -8403.0
ARHGEF19 -8415.0
ESYT1 -8443.0
ARHGAP39 -8479.0
GNA13 -8637.0
ARHGEF39 -9064.0
FAM13B -9516.0


REACTOME_CD28_CO_STIMULATION

REACTOME_CD28_CO_STIMULATION
637
set REACTOME_CD28_CO_STIMULATION
setSize 32
pANOVA 0.00124
s.dist 0.33
p.adjustANOVA 0.0597



Top enriched genes

Top 20 genes
GeneID Gene Rank
LCK 10594
PDPK1 9459
PIK3R1 8263
CD80 8236
RAC1 8122
CD28 8118
GRAP2 8091
SRC 8026
AKT2 7901
TRIB3 7514
PRR5 7473
AKT3 7414
AKT1 7231
LYN 6800
MAP3K14 6794
PAK2 6728
MLST8 6512
MTOR 6428
CDC42 6139
PIK3R2 5878

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
LCK 10594
PDPK1 9459
PIK3R1 8263
CD80 8236
RAC1 8122
CD28 8118
GRAP2 8091
SRC 8026
AKT2 7901
TRIB3 7514
PRR5 7473
AKT3 7414
AKT1 7231
LYN 6800
MAP3K14 6794
PAK2 6728
MLST8 6512
MTOR 6428
CDC42 6139
PIK3R2 5878
MAPKAP1 5820
FYN 4117
GRB2 152
VAV1 -2494
PAK1 -2523
PIK3R3 -3645
YES1 -4284
PIK3CA -5583
RICTOR -6156
THEM4 -6288
MAP3K8 -8129
CD86 -9525


REACTOME_SARS_COV_1_ACTIVATES_MODULATES_INNATE_IMMUNE_RESPONSES

REACTOME_SARS_COV_1_ACTIVATES_MODULATES_INNATE_IMMUNE_RESPONSES
1551
set REACTOME_SARS_COV_1_ACTIVATES_MODULATES_INNATE_IMMUNE_RESPONSES
setSize 39
pANOVA 0.00128
s.dist -0.298
p.adjustANOVA 0.06



Top enriched genes

Top 20 genes
GeneID Gene Rank
STING1 -11042
SFTPD -10550
BST2 -10425
NFKBIA -10413
TBK1 -10313
CASP1 -9494
TOMM70 -9371
PPIH -9010
NMI -8379
IRF3 -8235
KPNB1 -8106
RIGI -7847
IFIH1 -7381
KPNA2 -7242
PPIA -6821
UBA52 -6801
UBC -6316
RPS27A -5186
FKBP1A -5100
TRAF6 -4779

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
STING1 -11042
SFTPD -10550
BST2 -10425
NFKBIA -10413
TBK1 -10313
CASP1 -9494
TOMM70 -9371
PPIH -9010
NMI -8379
IRF3 -8235
KPNB1 -8106
RIGI -7847
IFIH1 -7381
KPNA2 -7242
PPIA -6821
UBA52 -6801
UBC -6316
RPS27A -5186
FKBP1A -5100
TRAF6 -4779
RIPK3 -4070
NLRP3 -4066
TRIM25 -3912
RELA -3044
ITCH -3021
PPIG -2506
RUNX1 243
SIKE1 842
PCBP2 1054
NFKB1 1146
PPIB 3075
MAVS 3718
UBB 4462
IRAK2 4637
PYCARD 5085
RCAN3 5403
TKFC 5858
TRAF3 7256
IKBKE 9564


REACTOME_RHOA_GTPASE_CYCLE

REACTOME_RHOA_GTPASE_CYCLE
1345
set REACTOME_RHOA_GTPASE_CYCLE
setSize 142
pANOVA 0.00152
s.dist 0.154
p.adjustANOVA 0.0695



Top enriched genes

Top 20 genes
GeneID Gene Rank
ARHGEF5 10564
ARAP3 10534
ARHGAP9 10444
ARHGDIA 9595
PREX1 9399
PLEKHG3 9378
ARHGAP45 9175
FMNL3 9022
PKN1 8915
DIAPH1 8803
ARHGEF25 8637
DEF6 8490
MCAM 8290
PIK3R1 8263
TAGAP 8114
ARHGEF4 8030
TRIO 7734
MYO9B 7729
ANLN 7390
ARHGAP1 7325

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ARHGEF5 10564
ARAP3 10534
ARHGAP9 10444
ARHGDIA 9595
PREX1 9399
PLEKHG3 9378
ARHGAP45 9175
FMNL3 9022
PKN1 8915
DIAPH1 8803
ARHGEF25 8637
DEF6 8490
MCAM 8290
PIK3R1 8263
TAGAP 8114
ARHGEF4 8030
TRIO 7734
MYO9B 7729
ANLN 7390
ARHGAP1 7325
PLEKHG5 7232
PLEKHG6 7197
ACTC1 7022
PKN3 6822
HMOX2 6671
VAV2 6650
SOWAHC 6391
ARHGAP18 6284
ARHGAP29 6274
STK10 6264
ROCK1 6122
ARHGEF3 6082
PIK3R2 5878
AAAS 5713
DOCK2 5516
ARAP1 5425
DIAPH3 5410
DDRGK1 5346
MYO9A 5262
ECT2 5168
ARAP2 5162
BCR 5105
ARHGEF7 5050
ARHGAP35 5006
ABR 4989
ARHGEF2 4912
TEX2 4787
ARHGEF10L 4663
ARHGDIB 4552
ARHGEF11 4551
ARHGEF28 4434
YKT6 4146
ARHGAP11A 3954
ARHGEF1 3913
ARHGEF17 3857
ARHGEF10 3735
FARP1 3461
ARHGEF18 3385
NET1 3140
FAM13A 2997
FLOT1 2832
STARD13 2826
FLOT2 2736
PLEKHG4 2648
ARHGAP26 2510
ARHGEF40 2435
TIAM1 2402
VANGL1 2301
ARHGAP30 2223
NGEF 2216
PLD1 1626
CCDC115 1579
RHPN1 1563
CIT 1504
ARHGAP10 1428
EMC3 1384
OBSCN 1267
ABCD3 1231
VAPB 992
AKAP13 883
DAAM1 838
RASGRF2 804
ARHGAP31 710
ARHGAP24 686
LBR 652
ROCK2 597
IQGAP1 580
ACBD5 422
ARHGEF15 39
ARHGAP21 -131
IQGAP3 -217
KALRN -313
ARHGAP19 -410
PCDH7 -743
SNAP23 -766
VAV3 -820
SRGAP1 -859
ARHGAP32 -866
RHPN2 -1043
LMAN1 -1137
ARHGAP20 -1183
TFRC -1295
VAMP3 -1296
DEPDC1B -1325
ARHGAP23 -1331
C1QBP -1647
ERBIN -1963
CAVIN1 -2315
VAV1 -2494
ARHGAP5 -2571
SCFD1 -2751
ARHGEF12 -2842
STBD1 -2888
STOM -2954
MCF2L -3089
STX5 -3231
TJP2 -3388
ARHGAP22 -3544
RACGAP1 -3568
PREX2 -3721
FAF2 -3800
KTN1 -3843
TMEM87A -4566
RTKN -4829
SLK -4834
GMIP -4890
ARHGAP8 -5135
RHOA -5826
PKN2 -6166
ARHGAP28 -6317
MACO1 -6360
ARHGAP42 -6382
ARHGAP44 -6782
CAV1 -6823
PGRMC2 -7028
DLC1 -8278
TMPO -8403
ARHGEF19 -8415
ARHGAP39 -8479
ARHGAP40 -8486
ARHGAP11B -9488
JUP -9734


REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS

REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS
194
set REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS
setSize 20
pANOVA 0.00174
s.dist 0.404
p.adjustANOVA 0.0772



Top enriched genes

Top 20 genes
GeneID Gene Rank
LCK 10594
AP1B1 9032
AP1M1 8678
CD28 8118
CD8B 8086
AP1M2 8006
CD4 7785
PACS1 6964
AP1S3 6744
AP1S1 6175
AP2A2 5798
ARF1 5126
AP1G1 4903
AP2M1 3974
AP2B1 755
ATP6V1H 752
AP2A1 -2362
HLA-A -3407
AP2S1 -4124
B2M -4432

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
LCK 10594
AP1B1 9032
AP1M1 8678
CD28 8118
CD8B 8086
AP1M2 8006
CD4 7785
PACS1 6964
AP1S3 6744
AP1S1 6175
AP2A2 5798
ARF1 5126
AP1G1 4903
AP2M1 3974
AP2B1 755
ATP6V1H 752
AP2A1 -2362
HLA-A -3407
AP2S1 -4124
B2M -4432


REACTOME_RHOB_GTPASE_CYCLE

REACTOME_RHOB_GTPASE_CYCLE
1369
set REACTOME_RHOB_GTPASE_CYCLE
setSize 67
pANOVA 0.00195
s.dist 0.219
p.adjustANOVA 0.0842



Top enriched genes

Top 20 genes
GeneID Gene Rank
ARHGEF5 10564
PREX1 9399
RHOB 8992
PKN1 8915
DIAPH1 8803
ARHGEF25 8637
MCAM 8290
PIK3R1 8263
ARHGDIG 7743
MYO9B 7729
ANLN 7390
ARHGAP1 7325
ACTC1 7022
PKN3 6822
VAV2 6650
SOWAHC 6391
STK10 6264
ROCK1 6122
ARHGEF3 6082
PIK3R2 5878

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ARHGEF5 10564
PREX1 9399
RHOB 8992
PKN1 8915
DIAPH1 8803
ARHGEF25 8637
MCAM 8290
PIK3R1 8263
ARHGDIG 7743
MYO9B 7729
ANLN 7390
ARHGAP1 7325
ACTC1 7022
PKN3 6822
VAV2 6650
SOWAHC 6391
STK10 6264
ROCK1 6122
ARHGEF3 6082
PIK3R2 5878
DIAPH3 5410
MYO9A 5262
ECT2 5168
BCR 5105
ARHGAP35 5006
ABR 4989
ARHGEF2 4912
ARHGEF10L 4663
ARHGEF11 4551
ARHGEF28 4434
ARHGEF1 3913
ARHGEF17 3857
ARHGEF10 3735
NET1 3140
FLOT1 2832
STARD13 2826
FLOT2 2736
ARHGAP26 2510
VANGL1 2301
CIT 1504
AKAP13 883
DAAM1 838
ROCK2 597
ARHGAP21 -131
IQGAP3 -217
PCDH7 -743
SNAP23 -766
ARHGAP32 -866
RHPN2 -1043
TFRC -1295
VAMP3 -1296
DEPDC1B -1325
ERBIN -1963
CAVIN1 -2315
ARHGAP5 -2571
ARHGEF12 -2842
STOM -2954
MCF2L -3089
TJP2 -3388
RACGAP1 -3568
RTKN -4829
SLK -4834
PKN2 -6166
CAV1 -6823
DLC1 -8278
ARHGAP39 -8479
JUP -9734


REACTOME_SARS_COV_1_INFECTION

REACTOME_SARS_COV_1_INFECTION
1539
set REACTOME_SARS_COV_1_INFECTION
setSize 136
pANOVA 0.00211
s.dist -0.153
p.adjustANOVA 0.0888



Top enriched genes

Top 20 genes
GeneID Gene Rank
STING1 -11042
SFTPD -10550
BST2 -10425
RPS6 -10417
NFKBIA -10413
TBK1 -10313
MOGS -10267
TMPRSS2 -10168
RPSA -9995
RPS2 -9929
RPS13 -9755
CASP1 -9494
TOMM70 -9371
PPIH -9010
GSK3A -8722
PSMC6 -8596
YWHAE -8482
NMI -8379
HNRNPA1 -8376
DDX5 -8307

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
STING1 -11042
SFTPD -10550
BST2 -10425
RPS6 -10417
NFKBIA -10413
TBK1 -10313
MOGS -10267
TMPRSS2 -10168
RPSA -9995
RPS2 -9929
RPS13 -9755
CASP1 -9494
TOMM70 -9371
PPIH -9010
GSK3A -8722
PSMC6 -8596
YWHAE -8482
NMI -8379
HNRNPA1 -8376
DDX5 -8307
RPS8 -8297
IRF3 -8235
RPS11 -8218
KPNB1 -8106
PKLR -7858
RIGI -7847
MAP1LC3B -7759
IFIH1 -7381
CHMP2B -7362
KPNA2 -7242
RPS18 -7152
CHMP4C -7073
RB1 -7068
CAV1 -6823
PPIA -6821
UBA52 -6801
RPS20 -6503
RPS26 -6380
FAU -6321
UBC -6316
GALNT1 -6280
RPS7 -6226
RPS27L -5336
RPS27A -5186
FKBP1A -5100
RPS16 -5010
EP300 -4854
TRAF6 -4779
PARP9 -4697
YWHAG -4529
RPS5 -4476
PARP8 -4437
RPS25 -4396
EEF1A1 -4286
SERPINE1 -4233
RIPK3 -4070
NLRP3 -4066
YWHAZ -4048
NPM1 -3970
TRIM25 -3912
RPS21 -3340
RELA -3044
ITCH -3021
PIK3C3 -2548
PPIG -2506
ST3GAL2 -2385
RPS19 -2325
RPS29 -2223
BECN1 -2149
RPS9 -1875
SUMO1 -1732
ST3GAL4 -1452
PARP10 -1423
RPS12 -1300
BCL2L1 -1138
YWHAH -1106
CHMP3 -961
PARP4 -886
CTSL -721
SMAD4 -536
UVRAG -122
GSK3B 35
CHMP2A 55
RUNX1 243
YWHAQ 560
RPS15A 633
CANX 806
SIKE1 842
RPS28 847
PCBP2 1054
NFKB1 1146
RPS23 1371
MGAT1 1431
CHMP4B 1816
RPS10 1817
RPS27 1846
RPS3 2010
ST6GALNAC3 2103
SFN 2141
GANAB 2172
RPS14 2461
PALS1 2521
ST6GAL1 2563
YWHAB 2669
RPS24 2982
PPIB 3075
PIK3R4 3173
PRKCSH 3298
CHMP7 3421
RPS15 3636
MAVS 3718
ZCRB1 4438
UBB 4462
IRAK2 4637
PARP14 4638
SP1 4737
PYCARD 5085
VHL 5171
RCAN3 5403
RPS3A 5749
TKFC 5858
UBE2I 5866
VCP 6187
ST6GALNAC4 6287
SMAD3 7074
PARP16 7089
TRAF3 7256
ST3GAL1 7931
CHMP6 8376
ST3GAL3 9059
RIPK1 9142
CHMP4A 9314
PDPK1 9459
IKBKE 9564
ST6GALNAC2 9644
PARP6 10356


REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION

REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION
1193
set REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION
setSize 250
pANOVA 0.00225
s.dist 0.112
p.adjustANOVA 0.0907



Top enriched genes

Top 20 genes
GeneID Gene Rank
GNB3 10775
ORM2 10683
GP1BB 10640
LCK 10594
SERPINA4 10320
CD9 10281
GNGT2 10236
CSK 10156
RAC2 10136
ISLR 10114
FCER1G 9858
HGF 9684
PDPK1 9459
ITIH3 9353
ACTN1 9315
VEGFB 9311
DGKD 9193
TF 9166
PIK3R6 9156
APOA1 9038

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GNB3 10775
ORM2 10683
GP1BB 10640
LCK 10594
SERPINA4 10320
CD9 10281
GNGT2 10236
CSK 10156
RAC2 10136
ISLR 10114
FCER1G 9858
HGF 9684
PDPK1 9459
ITIH3 9353
ACTN1 9315
VEGFB 9311
DGKD 9193
TF 9166
PIK3R6 9156
APOA1 9038
RHOB 8992
FGG 8841
CTSW 8814
TLN1 8790
A1BG 8721
PRKCQ 8542
P2RY12 8469
PSAP 8462
DGKZ 8435
CYRIB 8398
PIK3R1 8263
CLEC1B 8212
RAC1 8122
SRC 8026
PRKCH 7881
QSOX1 7762
GNG4 7647
SYK 7645
ACTN4 7487
LGALS3BP 7471
KNG1 7465
PIK3R5 7450
PPBP 7394
PLG 7357
AKT1 7231
PCYOX1L 7224
RASGRP1 7200
ITIH4 7195
ABHD12 6985
TGFB3 6943
FGB 6886
GNG12 6873
LYN 6800
APLP2 6729
STXBP2 6690
VAV2 6650
TAGLN2 6601
DGKA 6600
COL1A1 6443
PTPN6 6359
PRKCD 6332
CDC42 6139
GNAI2 6080
RAF1 6019
PIK3R2 5878
MGLL 5816
APBB1IP 5806
ACTN2 5616
ADRA2C 5570
BRPF3 5546
CHID1 5539
PLCG2 5491
GNAI1 5459
TGFB2 5394
TEX264 5385
A2M 4959
DAGLB 4783
GNG7 4722
CRK 4716
PTPN1 4415
MAPK1 4404
ITPR2 4400
F2R 4344
GNG2 4324
FYN 4117
MPIG6B 4081
GNB1 3921
PECAM1 3840
ITPR3 3822
GP9 3767
RASGRP2 3748
MAPK3 3720
GNA14 3646
ARRB1 3591
RARRES2 3584
RAP1A 3553
PRKCA 3441
PDGFA 3410
ADRA2B 3365
LCP2 3293
DGKQ 3144
PLA2G4A 3000
HRG 2939
CFL1 2933
PROS1 2798
DGKH 2427
VEGFC 2405
SERPING1 2347
DGKE 2167
EGF 2164
STXBP3 2136
SCCPDH 2090
PRKCB 1981
ITPR1 1953
TOR4A 1928
SERPINA1 1923
ITGA2B 1909
GNA15 1546
DGKG 1449
GNB5 1330
RAPGEF3 1288
TUBA4A 1191
P2RY1 1171
VWF 1155
VCL 1081
TGFB1 1028
IGF2 1002
PIK3CB 975
DGKI 864
TRPC6 840
ECM1 835
APP 815
FAM3C 812
ABHD6 796
GNB4 731
CD36 618
NHLRC2 569
BCAR1 510
ITGB3 470
GNAQ 436
TBXA2R 391
LEFTY2 372
TRPC7 244
GRB2 152
GNA12 71
MAPK14 -47
PRKCE -277
CD109 -393
FN1 -458
CDC37L1 -466
SPARC -539
RAP1B -559
GNA11 -655
PCDH7 -743
LY6G6F -748
DAGLA -797
VAV3 -820
PTPN11 -957
PHACTR2 -968
SOS1 -1066
THPO -1092
CALM1 -1130
GNG13 -1387
THBS1 -1415
RAPGEF4 -1422
GTPBP2 -1703
PLEK -1710
GNG11 -1757
F2RL2 -1888
PRKCZ -1979
GP6 -2005
PF4 -2109
ADRA2A -2113
SPP2 -2129
F2 -2224
FERMT3 -2255
PTK2 -2288
OLA1 -2335
CD63 -2428
ABCC4 -2467
VAV1 -2494
GP5 -2529
GNG5 -2583
F13A1 -2645
HSPA5 -2669
PIK3CG -2882
TTN -2899
WDR1 -2959
ALDOA -3097
IGF1 -3226
LAT -3349
CLU -3582
PIK3R3 -3645
ARRB2 -3663
PFN1 -3702
STX4 -4002
HABP4 -4003
YWHAZ -4048
VTI1B -4110
SERPINE1 -4233
GNAT3 -4448
RAB27B -4508
SELP -4510
FGA -4581
CAP1 -4918
F2RL3 -5009
SCG3 -5035
LHFPL2 -5082
MPL -5144
TMX3 -5156
F5 -5273
CYB5R1 -5455
GNG3 -5571
PIK3CA -5583
RHOA -5826
TRPC3 -6012
MMRN1 -6056
CALU -6058
PDPN -6071
GNG10 -6129
ANXA5 -6470
PDGFB -6533
AHSG -6575
SRGN -6579
ALB -6630
RHOG -6637
AAMP -6675
GNB2 -6742
PPIA -6821
COL1A2 -7059
GNAI3 -7543
SOD1 -7677
PRKCG -7785
CFD -8023
DGKB -8102
GNGT1 -8192
SERPINF2 -8447
GNA13 -8637
GNG8 -8827
APOH -9089
VEGFA -9097
SERPINA3 -9207
MANF -9299
TIMP3 -9519
ENDOD1 -9647
ORM1 -9881
SHC1 -9953
CLEC3B -10361
SELENOP -10542
GP1BA -10752


REACTOME_CELL_CYCLE_CHECKPOINTS

REACTOME_CELL_CYCLE_CHECKPOINTS
1120
set REACTOME_CELL_CYCLE_CHECKPOINTS
setSize 284
pANOVA 0.00227
s.dist -0.105
p.adjustANOVA 0.0907



Top enriched genes

Top 20 genes
GeneID Gene Rank
SKA1 -10474
CCNE2 -10221
H4C1 -9861
ZWINT -9760
RBBP8 -9701
PSMB8 -9663
CDC45 -9610
ANAPC15 -9537
CENPH -9492
CENPM -9403
SPC24 -9314
PSMB9 -9156
CDC23 -9096
SGO2 -8914
NUF2 -8895
PSMB6 -8884
PSMB11 -8782
PSMC6 -8596
BUB3 -8515
CENPE -8497

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SKA1 -10474.0
CCNE2 -10221.0
H4C1 -9861.0
ZWINT -9760.0
RBBP8 -9701.0
PSMB8 -9663.0
CDC45 -9610.0
ANAPC15 -9537.0
CENPH -9492.0
CENPM -9403.0
SPC24 -9314.0
PSMB9 -9156.0
CDC23 -9096.0
SGO2 -8914.0
NUF2 -8895.0
PSMB6 -8884.0
PSMB11 -8782.0
PSMC6 -8596.0
BUB3 -8515.0
CENPE -8497.0
YWHAE -8482.0
XPO1 -8435.0
SPC25 -8412.0
WEE1 -8318.0
B9D2 -8304.0
SEH1L -8298.0
CDKN1B -8228.0
MCM5 -8148.0
RAD1 -8135.0
CENPC -8131.0
PSMB4 -7922.0
MAD2L1 -7849.0
ANAPC1 -7673.0
DNA2 -7655.0
RHNO1 -7548.0
PSMD12 -7515.0
PSMD9 -7320.0
EXO1 -7294.0
PSMD14 -7231.0
PPP2CA -7146.0
ORC3 -7128.0
ZWILCH -7094.0
CHEK2 -7011.0
CENPA -6977.0
TP53BP1 -6839.0
UBA52 -6801.0
DBF4 -6772.0
PMF1 -6759.0
ANAPC11 -6670.0
PSMD4 -6582.0
ORC2 -6518.0
PCBP4 -6477.0
MCM8 -6418.0
DSN1 -6320.0
UBC -6316.0
RAD17 -6301.0
MAPRE1 -6261.0
ORC6 -6213.0
CDC25A -6142.0
MCM2 -6125.0
SEC13 -5971.0
MIS12 -5938.0
CLSPN -5918.0
PPP2R5D -5910.0
DYNLL1 -5861.0
NUP43 -5857.0
PSMD5 -5814.0
H2BC1 -5805.0
CCNA2 -5676.0
PSME1 -5657.0
TAOK1 -5648.0
NUP37 -5559.0
PSMA2 -5475.0
MCM10 -5362.0
MCM6 -5361.0
SEM1 -5318.0
H2BC15 -5237.0
RPS27A -5186.0
CENPK -5180.0
CCNA1 -5158.0
H2BC7 -5146.5
PPP2R1A -5096.0
KIF2B -4931.0
KIF2C -4885.0
BLM -4880.0
PSMA6 -4797.0
KIF18A -4735.0
H4C13 -4659.0
PSMB10 -4647.0
RAD9B -4553.0
RAD50 -4547.0
H2AX -4544.0
YWHAG -4529.0
H4C4 -4490.0
UBE2N -4353.0
CDC20 -4306.0
NSL1 -4256.0
CDKN1A -4217.0
MDC1 -4185.0
YWHAZ -4048.0
GTSE1 -3959.0
CENPN -3878.0
RFC3 -3831.0
PSMC5 -3766.0
AURKB -3669.0
PSMC3 -3596.0
H2BC5 -3590.0
SGO1 -3585.0
CDC7 -3293.0
MCM4 -3266.0
H2BC13 -3197.0
H4C3 -3175.0
ORC1 -3151.0
MRE11 -3107.0
PSMB1 -2993.0
AHCTF1 -2974.0
CENPO -2968.0
PLK1 -2865.0
KAT5 -2846.0
CDC27 -2821.0
ANAPC10 -2801.0
RPA2 -2757.0
PSMD8 -2756.0
H2BC10 -2688.0
PSMB7 -2674.0
H4C5 -2560.0
CDK2 -2539.0
KNL1 -2515.0
CKAP5 -2464.0
PSMD7 -2423.0
H2BC21 -2387.0
RANBP2 -2371.0
ATR -2361.0
H4C8 -2282.0
NUDC -2181.0
DYNC1I2 -2130.0
CENPS -2075.0
H2BC14 -1854.0
UBE2E1 -1821.0
NUP98 -1787.0
PSME4 -1747.0
CDK1 -1714.0
ANAPC4 -1598.0
ATM -1566.0
NDE1 -1553.0
UBE2S -1552.0
CCNB1 -1461.0
KNTC1 -1394.0
ZW10 -1259.0
RNF168 -1197.0
YWHAH -1106.0
PKMYT1 -1059.0
SKA2 -1002.0
RMI1 -904.0
BUB1 -901.0
BIRC5 -702.0
CCNB2 -677.0
RFC2 -610.0
CDC25C -492.0
NDC80 -332.0
CENPF -326.0
PSME3 -213.0
CDKN2A -111.0
ORC4 -19.0
BRCA1 68.0
H2BC6 90.0
PSMA8 102.0
RFC4 130.0
PSMB2 204.0
RNF8 209.0
ITGB3BP 228.0
PSMD3 413.0
PPP2R5B 439.0
MCM7 455.0
BUB1B 508.0
YWHAQ 560.0
PSMC1 563.0
ABRAXAS1 636.0
H4C6 711.0
NUP160 766.0
PSMC2 780.0
PPP2R5E 784.0
DYNC1H1 846.0
ANAPC7 997.0
UBE2C 1092.0
CLASP1 1107.0
H2BC8 1285.0
TOP3A 1315.0
H4C2 1432.0
DYNC1LI1 1464.0
COP1 1479.0
PSME2 1567.0
H4C16 1648.0
PSMF1 1681.0
PHF20 1695.0
PSMA4 1711.0
NUP107 1840.0
RPS27 1846.0
CENPU 1878.0
PSMB5 1998.0
H2BC11 2126.0
SFN 2141.0
NSD2 2146.0
CENPT 2225.0
ANAPC16 2248.0
PSMA7 2284.0
CDC16 2338.0
CENPL 2376.0
H3-4 2378.0
NUP85 2441.0
CCNE1 2460.0
UBE2D1 2470.0
CENPP 2484.0
YWHAB 2669.0
ANAPC5 2686.0
CENPQ 2705.0
PSMD11 2717.0
RFC5 2789.0
H2BC12 2999.0
RMI2 3099.0
ORC5 3123.0
BABAM1 3254.0
DYNC1I1 3356.0
CDCA8 3384.0
H2BC26 3442.0
INCENP 3471.0
PSMA3 3474.0
TOPBP1 3532.0
ANAPC2 3537.0
RPA3 3737.0
BARD1 3826.0
PSMD1 3904.0
PPP2R5C 3911.0
PPP2R5A 3918.0
CDC26 4020.0
NUP133 4054.0
CLIP1 4115.0
DYNC1LI2 4150.0
BABAM2 4151.0
HERC2 4232.0
H2BC17 4334.0
UBB 4462.0
HUS1 4791.0
WRN 4809.0
CHEK1 4963.0
MDM4 5136.0
NBN 5285.0
TP53 5315.0
H2BC4 5571.0
ATRIP 5649.0
UBE2V2 5662.0
BRIP1 5714.0
PPP1CC 5761.0
PSMD2 5837.0
MDM2 5847.0
H4C9 5861.0
H4C12 5863.0
MAD1L1 6595.0
PPP2CB 6598.0
PSMA5 6687.0
H2BC3 6745.0
RPA1 6866.0
NDEL1 7021.0
SPDL1 7032.0
PPP2R1B 7101.0
PAFAH1B1 7265.0
PSMC4 7451.0
PSMD6 7550.0
PSMA1 7633.0
RAD9A 7910.0
UIMC1 8042.0
MCM3 8167.0
RANGAP1 8224.0
RCC2 8360.0
PSMD13 8449.0
CLASP2 8727.0
PSMB3 8759.0
CDC6 8920.0
H2BC9 8981.5
PIAS4 9089.0
ZNF385A 9303.0
KIF2A 9935.0
H4C11 10159.0
DYNLL2 10336.0


REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY

REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY
1591
set REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY
setSize 33
pANOVA 0.00232
s.dist -0.306
p.adjustANOVA 0.0907



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS6 -10417
RPSA -9995
RPS2 -9929
RPS13 -9755
HNRNPA1 -8376
RPS8 -8297
RPS11 -8218
RPS18 -7152
RPS20 -6503
RPS26 -6380
FAU -6321
RPS7 -6226
RPS27L -5336
RPS27A -5186
RPS16 -5010
RPS5 -4476
RPS25 -4396
EEF1A1 -4286
RPS21 -3340
RPS19 -2325

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS6 -10417
RPSA -9995
RPS2 -9929
RPS13 -9755
HNRNPA1 -8376
RPS8 -8297
RPS11 -8218
RPS18 -7152
RPS20 -6503
RPS26 -6380
FAU -6321
RPS7 -6226
RPS27L -5336
RPS27A -5186
RPS16 -5010
RPS5 -4476
RPS25 -4396
EEF1A1 -4286
RPS21 -3340
RPS19 -2325
RPS29 -2223
RPS9 -1875
RPS12 -1300
RPS15A 633
RPS28 847
RPS23 1371
RPS10 1817
RPS27 1846
RPS3 2010
RPS14 2461
RPS24 2982
RPS15 3636
RPS3A 5749


REACTOME_MITOCHONDRIAL_TRANSLATION

REACTOME_MITOCHONDRIAL_TRANSLATION
874
set REACTOME_MITOCHONDRIAL_TRANSLATION
setSize 93
pANOVA 0.00238
s.dist -0.182
p.adjustANOVA 0.0909



Top enriched genes

Top 20 genes
GeneID Gene Rank
MRPS34 -9744
ERAL1 -9670
MRPS17 -9630
MRPL34 -9575
MRPS18A -9454
MRPS24 -8684
MRPL46 -8636
MRPS33 -8522
MRPL53 -8402
MRPL40 -8390
MRPL16 -7970
MRPL19 -7795
MRPL21 -7761
MRPS23 -7662
MRPS30 -7650
OXA1L -7406
MRPL47 -7222
MRPL51 -7049
MRPL58 -7047
MRPL49 -6995

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MRPS34 -9744
ERAL1 -9670
MRPS17 -9630
MRPL34 -9575
MRPS18A -9454
MRPS24 -8684
MRPL46 -8636
MRPS33 -8522
MRPL53 -8402
MRPL40 -8390
MRPL16 -7970
MRPL19 -7795
MRPL21 -7761
MRPS23 -7662
MRPS30 -7650
OXA1L -7406
MRPL47 -7222
MRPL51 -7049
MRPL58 -7047
MRPL49 -6995
MRPL10 -6732
DAP3 -6621
MRPS18C -6414
MRPS12 -6374
MTIF3 -6202
TSFM -6171
MRPS9 -6017
MRPL3 -5920
MRPL18 -5791
MRPS14 -5593
MRPL54 -5533
MRPS2 -5411
MRPL50 -5259
MRPL11 -5131
MRPL39 -4844
MRPL42 -4604
MRPS26 -4533
MRPL37 -4525
MTIF2 -4140
MRPS15 -3887
MRPL35 -3462
MRPL57 -3251
MTRF1L -3193
MRPL52 -3108
MRPL28 -3016
MRPL32 -2998
MRPS18B -2330
MRPL24 -2290
MRPS7 -2194
GFM2 -1790
MRPL44 -1755
MRPL17 -1472
MRPS28 -1421
MRPL27 -1190
MRPL12 -1168
MRPS16 -1107
MRRF -1019
MRPS11 -657
MRPL15 -429
MRPL20 -254
MRPL43 -77
MRPL9 41
MRPL30 141
TUFM 548
MTFMT 590
MRPL2 639
MRPL38 769
MRPS35 1209
MRPS22 1425
MRPL55 1458
MRPS5 1473
MRPS31 1491
MRPL48 1578
MRPL1 2041
MRPL45 2649
MRPL14 2881
MRPS27 3037
MRPS6 3106
MRPL22 3193
AURKAIP1 3581
MRPL36 4832
CHCHD1 4859
MRPS21 5457
MRPL4 5496
MRPL23 6003
MRPL33 6377
MRPS10 6645
MRPS25 6871
PTCD3 6924
GADD45GIP1 7641
MRPL13 7779
GFM1 8612
MRPL41 9891


REACTOME_MITOTIC_G2_G2_M_PHASES

REACTOME_MITOTIC_G2_G2_M_PHASES
816
set REACTOME_MITOTIC_G2_G2_M_PHASES
setSize 194
pANOVA 0.00247
s.dist -0.126
p.adjustANOVA 0.0923



Top enriched genes

Top 20 genes
GeneID Gene Rank
HAUS5 -10433
TUBAL3 -10277
MZT2B -9951
PSMB8 -9663
TUBA1B -9443
LIN9 -9289
PSMB9 -9156
TUBG1 -8922
PSMB6 -8884
MZT2A -8829
DCTN2 -8826
PSMB11 -8782
HMMR -8760
PPME1 -8695
HAUS3 -8612
AURKA -8606
PSMC6 -8596
TUBB4A -8498
LCMT1 -8495
YWHAE -8482

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
HAUS5 -10433
TUBAL3 -10277
MZT2B -9951
PSMB8 -9663
TUBA1B -9443
LIN9 -9289
PSMB9 -9156
TUBG1 -8922
PSMB6 -8884
MZT2A -8829
DCTN2 -8826
PSMB11 -8782
HMMR -8760
PPME1 -8695
HAUS3 -8612
AURKA -8606
PSMC6 -8596
TUBB4A -8498
LCMT1 -8495
YWHAE -8482
XPO1 -8435
CDK7 -8404
NME7 -8400
WEE1 -8318
PHLDA1 -8260
TUBA3E -8172
CEP135 -7947
NEK2 -7927
PSMB4 -7922
ALMS1 -7909
TUBGCP6 -7888
PSMD12 -7515
CENPJ -7429
CEP70 -7388
TUBB3 -7345
PSMD9 -7320
OPTN -7311
MYBL2 -7253
PSMD14 -7231
FOXM1 -7178
PPP2CA -7146
CDK11A -6968
CEP152 -6935
UBA52 -6801
PSMD4 -6582
TUBB2A -6353
UBC -6316
MAPRE1 -6261
CDC25A -6142
CEP43 -6123
HAUS2 -6106
TUBA4B -5985
DYNLL1 -5861
LIN37 -5823
PSMD5 -5814
HSP90AA1 -5799
CCNA2 -5676
PSME1 -5657
PSMA2 -5475
SEM1 -5318
RBBP4 -5281
RPS27A -5186
ACTR1A -5178
CCNA1 -5158
PPP2R1A -5096
TUBB -4906
EP300 -4854
PSMA6 -4797
TPX2 -4780
LIN54 -4721
RAB8A -4654
PSMB10 -4647
CEP63 -4637
YWHAG -4529
ODF2 -4447
CSNK1E -4241
CDKN1A -4217
LIN52 -4088
GTSE1 -3959
PSMC5 -3766
PSMC3 -3596
SSNA1 -3514
CCNH -3426
CUL1 -3240
MNAT1 -3025
PSMB1 -2993
FBXL7 -2986
HAUS4 -2951
PLK1 -2865
PSMD8 -2756
PSMB7 -2674
CDK2 -2539
CKAP5 -2464
PSMD7 -2423
TUBB8 -2320
HAUS1 -2197
SKP1 -2150
DYNC1I2 -2130
CDK5RAP2 -1975
TUBG2 -1962
PSME4 -1747
CDK1 -1714
NDE1 -1553
PLK4 -1533
CCNB1 -1461
E2F1 -1457
PCM1 -1375
CEP72 -1114
PKMYT1 -1059
CCNB2 -677
CDC25C -492
DCTN1 -415
CENPF -326
PSME3 -213
PRKAR2B -205
PPP1R12A -109
PSMA8 102
PSMB2 204
NINL 316
PSMD3 413
PSMC1 563
TUBB4B 746
PSMC2 780
DYNC1H1 846
CLASP1 1107
TUBA4A 1191
CCP110 1430
CEP290 1515
PSME2 1567
PSMF1 1681
PSMA4 1711
PCNT 1913
NEDD1 1927
PSMB5 1998
HSP90AB1 2011
PSMA7 2284
SFI1 2592
BORA 2698
PSMD11 2717
DCTN3 2794
PRKACA 2802
PPP1CB 2817
FBXL18 2839
FBXW11 2843
CEP192 2876
CEP57 3006
MZT1 3011
CEP131 3094
CEP76 3284
PSMA3 3474
CNTRL 3603
AJUBA 3702
PPP1R12B 3790
CEP164 3882
PSMD1 3904
TUBA1A 4010
SDCCAG8 4152
E2F3 4178
TUBGCP5 4255
CEP41 4373
UBB 4462
CDC25B 4567
PPP2R2A 4746
TUBA1C 4895
TUBB2B 5110
AKAP9 5154
BTRC 5196
TP53 5315
CEP78 5567
HAUS8 5778
PSMD2 5837
FKBPL 5920
RBX1 6251
PPP2CB 6598
PSMA5 6687
TUBA8 6777
HAUS6 6969
PPP2R1B 7101
TUBGCP3 7154
PAFAH1B1 7265
TUBGCP4 7355
PSMC4 7451
TUBGCP2 7508
PSMD6 7550
PSMA1 7633
TUBB1 7829
CEP250 7862
CDK11B 8012
PSMD13 8449
TUBB6 8755
PSMB3 8759
CSNK1D 8903
TUBA3C 9921
TUBA3D 10642


REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK

REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK
329
set REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK
setSize 53
pANOVA 0.00258
s.dist 0.239
p.adjustANOVA 0.0941



Top enriched genes

Top 20 genes
GeneID Gene Rank
ARHGEF5 10564
FGD3 9990
PREX1 9399
TIAM2 9123
ARHGEF16 8962
ARHGEF33 8873
ARHGEF37 8718
NGFR 8694
RAC1 8122
ARHGEF4 8030
TRIO 7734
PLEKHG2 7423
PLEKHG5 7232
VAV2 6650
ARHGEF3 6082
ECT2 5168
ARHGEF7 5050
ABR 4989
ARHGEF2 4912
ARHGEF10L 4663

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ARHGEF5 10564
FGD3 9990
PREX1 9399
TIAM2 9123
ARHGEF16 8962
ARHGEF33 8873
ARHGEF37 8718
NGFR 8694
RAC1 8122
ARHGEF4 8030
TRIO 7734
PLEKHG2 7423
PLEKHG5 7232
VAV2 6650
ARHGEF3 6082
ECT2 5168
ARHGEF7 5050
ABR 4989
ARHGEF2 4912
ARHGEF10L 4663
ARHGEF11 4551
ARHGEF1 3913
ARHGEF17 3857
ARHGEF10 3735
ARHGEF18 3385
ITSN1 3273
NET1 3140
ARHGEF40 2435
TIAM1 2402
NGEF 2216
NGF 2211
OBSCN 1267
MAPK8 1017
AKAP13 883
RASGRF2 804
SOS2 73
ARHGEF15 39
AATF -288
KALRN -313
ARHGEF38 -598
VAV3 -820
SOS1 -1066
BCL2L11 -1399
ARHGEF26 -2193
VAV1 -2494
ARHGEF12 -2842
MCF2L -3089
FGD4 -3623
BAD -4701
FGD2 -5484
ARHGEF19 -8415
GNA13 -8637
ARHGEF39 -9064


REACTOME_INTERFERON_ALPHA_BETA_SIGNALING

REACTOME_INTERFERON_ALPHA_BETA_SIGNALING
1432
set REACTOME_INTERFERON_ALPHA_BETA_SIGNALING
setSize 70
pANOVA 0.00265
s.dist -0.208
p.adjustANOVA 0.0946



Top enriched genes

Top 20 genes
GeneID Gene Rank
IFNA21 -10838
IFNA7 -10834
IFNA1 -10778
SOCS3 -10596
IFIT2 -10465
BST2 -10425
IFNA14 -10046
ISG15 -9963
IRF5 -9899
PSMB8 -9663
HLA-B -9281
IFITM1 -9141
IFNA2 -9041
IFIT1 -8888
USP18 -8617
IRF3 -8235
IFI27 -8190
KPNB1 -8106
RSAD2 -8096
HLA-H -7976

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
IFNA21 -10838
IFNA7 -10834
IFNA1 -10778
SOCS3 -10596
IFIT2 -10465
BST2 -10425
IFNA14 -10046
ISG15 -9963
IRF5 -9899
PSMB8 -9663
HLA-B -9281
IFITM1 -9141
IFNA2 -9041
IFIT1 -8888
USP18 -8617
IRF3 -8235
IFI27 -8190
KPNB1 -8106
RSAD2 -8096
HLA-H -7976
OAS3 -7937
IFNA8 -7791
HLA-G -7383
ADAR -7355
HLA-C -7307
HLA-F -7024
OASL -6929
IFIT5 -6725
IFI6 -6196
RNASEL -6175
OAS1 -5984
HLA-E -5353
IRF1 -4439
IFNA16 -4428
IRF9 -4386
HLA-A -3407
IFI35 -3306
KPNA1 -3170
IFNA13 -2934
ABCE1 -2802
IRF7 -2637
STAT2 -1485
PTPN11 -957
IRF6 -870
IRF4 527
SAMHD1 1261
IFIT3 1533
GBP2 1763
STAT1 1869
TYK2 2850
IFNA5 2890
IFNAR1 3464
IP6K2 3552
EGR1 3710
IRF2 3807
MX2 4096
SOCS1 4125
XAF1 4141
PTPN1 4415
IFNAR2 5737
PTPN6 6359
MX1 6827
OAS2 7754
IRF8 9535
ISG20 9724
JAK1 9739
IFITM2 9932
IFNA6 9955
IFITM3 10257
IFNB1 10578


REACTOME_INTERFERON_SIGNALING

REACTOME_INTERFERON_SIGNALING
1437
set REACTOME_INTERFERON_SIGNALING
setSize 193
pANOVA 0.00276
s.dist -0.125
p.adjustANOVA 0.0963



Top enriched genes

Top 20 genes
GeneID Gene Rank
IFNA21 -10838
IFNA7 -10834
IFNA1 -10778
VCAM1 -10682
KPNA7 -10650
SOCS3 -10596
IFIT2 -10465
BST2 -10425
HLA-DPA1 -10385
TRIM35 -10156
IFNA14 -10046
ISG15 -9963
IRF5 -9899
EIF4A2 -9888
GBP5 -9693
PSMB8 -9663
POM121 -9356
HLA-B -9281
TRIM22 -9252
IFITM1 -9141

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
IFNA21 -10838
IFNA7 -10834
IFNA1 -10778
VCAM1 -10682
KPNA7 -10650
SOCS3 -10596
IFIT2 -10465
BST2 -10425
HLA-DPA1 -10385
TRIM35 -10156
IFNA14 -10046
ISG15 -9963
IRF5 -9899
EIF4A2 -9888
GBP5 -9693
PSMB8 -9663
POM121 -9356
HLA-B -9281
TRIM22 -9252
IFITM1 -9141
IFNA2 -9041
TRIM21 -8976
IFIT1 -8888
POM121C -8815
USP18 -8617
SEH1L -8298
IRF3 -8235
IFI27 -8190
KPNB1 -8106
RSAD2 -8096
HERC5 -8065
HLA-H -7976
OAS3 -7937
HLA-DPB1 -7874
RIGI -7847
IFNA8 -7791
NUP155 -7766
EIF4E2 -7601
HLA-G -7383
ADAR -7355
HLA-C -7307
KPNA2 -7242
HLA-F -7024
OASL -6929
SMAD7 -6907
NUP58 -6850
UBA52 -6801
IFIT5 -6725
NUP54 -6598
UBC -6316
CAMK2D -6272
UBE2L6 -6214
IFI6 -6196
PDE12 -6182
RNASEL -6175
PPM1B -6075
EIF4G2 -6037
OAS1 -5984
SEC13 -5971
NUP43 -5857
NCAM1 -5793
TRIM38 -5766
NUP37 -5559
EIF4A3 -5476
HLA-E -5353
ARIH1 -5242
IFI30 -5220
RPS27A -5186
NUP153 -4963
IRF1 -4439
B2M -4432
IFNA16 -4428
IRF9 -4386
UBE2N -4353
NDC1 -4338
GBP6 -4297
TRIM25 -3912
ICAM1 -3910
TRIM2 -3709
NEDD4 -3597
EIF4A1 -3505
HLA-A -3407
TRIM26 -3382
JAK2 -3310
IFI35 -3306
TPR -3264
KPNA1 -3170
IFNA13 -2934
ABCE1 -2802
IRF7 -2637
CAMK2A -2499
EIF4G3 -2454
RANBP2 -2371
KPNA5 -2326
EIF4G1 -2048
UBE2E1 -1821
NUP98 -1787
SUMO1 -1732
TRIM34 -1725
NUP42 -1540
STAT2 -1485
SP100 -1205
TRIM62 -1120
TRIM29 -1048
HLA-DQA1 -1038
PTPN11 -957
PML -912
HLA-DQB1 -903
IRF6 -870
GBP7 -850
HLA-DRB5 -758
IFNGR2 -554
NUP214 -322
EIF2AK2 -283
GBP3 -25
NUP88 31
PLCG1 233
IRF4 527
NUP160 766
KPNA3 896
PTPN2 910
SAMHD1 1261
NUP50 1298
IFIT3 1533
EIF4E 1594
GBP2 1763
NUP107 1840
STAT1 1869
EIF4E3 1936
HLA-DQA2 2200
UBA7 2404
NUP85 2441
TRIM46 2662
TYK2 2850
IFNA5 2890
IFNG 2924
TRIM45 2981
TRIM8 3048
NUP205 3348
NUP62 3360
IFNAR1 3464
PIAS1 3497
IP6K2 3552
EGR1 3710
MAPK3 3720
NUP93 3792
IRF2 3807
KPNA4 3953
CD44 4044
NUP133 4054
MX2 4096
SOCS1 4125
XAF1 4141
CAMK2B 4293
PTPN1 4415
UBB 4462
PIN1 4691
TRIM14 4945
TRIM6 5108
TRIM31 5150
HLA-DRB1 5202
MT2A 5245
CIITA 5339
HLA-DRA 5373
TRIM10 5468
GBP1 5573
AAAS 5713
IFNAR2 5737
RAE1 5767
NUP188 5843
TRIM68 5854
TRIM5 5969
PRKCD 6332
PTPN6 6359
NUP35 6436
HLA-DQB2 6491
FLNB 6746
MX1 6827
GBP4 6828
TRIM17 7100
TRIM3 7407
OAS2 7754
NUP210 9050
IFNGR1 9398
CAMK2G 9407
IRF8 9535
PTAFR 9677
ISG20 9724
JAK1 9739
IFITM2 9932
IFNA6 9955
IFITM3 10257
IFNB1 10578


REACTOME_RRNA_MODIFICATION_IN_THE_NUCLEUS_AND_CYTOSOL

REACTOME_RRNA_MODIFICATION_IN_THE_NUCLEUS_AND_CYTOSOL
1046
set REACTOME_RRNA_MODIFICATION_IN_THE_NUCLEUS_AND_CYTOSOL
setSize 58
pANOVA 0.00282
s.dist -0.227
p.adjustANOVA 0.0964



Top enriched genes

Top 20 genes
GeneID Gene Rank
NOP10 -10749
RRP9 -10654
RPS6 -10417
RRP7A -10373
MPHOSPH10 -10209
RPS2 -9929
UTP11 -9667
GAR1 -9619
PWP2 -9352
IMP3 -9187
SNU13 -8416
DIMT1 -8299
THUMPD1 -7833
FCF1 -7729
UTP6 -6882
UTP4 -6688
WDR3 -6604
RPS7 -6226
NOP14 -5963
RRP36 -5769

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NOP10 -10749
RRP9 -10654
RPS6 -10417
RRP7A -10373
MPHOSPH10 -10209
RPS2 -9929
UTP11 -9667
GAR1 -9619
PWP2 -9352
IMP3 -9187
SNU13 -8416
DIMT1 -8299
THUMPD1 -7833
FCF1 -7729
UTP6 -6882
UTP4 -6688
WDR3 -6604
RPS7 -6226
NOP14 -5963
RRP36 -5769
NHP2 -5749
PNO1 -5564
NOP56 -5347
DDX49 -5272
DCAF13 -3553
UTP15 -3394
NOL6 -3365
BUD23 -2788
TRMT112 -2641
UTP3 -2346
NOL11 -2046
UTP14C -2028
RPS9 -1875
DHX37 -1763
UTP18 -1393
NAT10 -986
UTP25 -983
DDX47 -661
NOC4L -475
PDCD11 172
FBL 589
RCL1 783
EMG1 1661
NOP58 1756
IMP4 2153
WDR75 2180
RPS14 2461
WDR43 2974
NOP2 3222
WDR36 4187
KRR1 4298
DDX52 5531
TBL3 5786
WDR46 5790
HEATR1 6584
BMS1 7388
TSR3 7851
UTP20 8000


REACTOME_HEMOSTASIS

REACTOME_HEMOSTASIS
3
set REACTOME_HEMOSTASIS
setSize 591
pANOVA 0.00301
s.dist 0.0714
p.adjustANOVA 0.101



Top enriched genes

Top 20 genes
GeneID Gene Rank
VPREB3 10789
GNB3 10775
CEACAM1 10746
ORM2 10683
TUBA3D 10642
GP1BB 10640
LCK 10594
IFNB1 10578
SLC7A5 10514
PSG11 10453
SERPINB2 10365
MAFF 10364
VPREB1 10351
SERPINA4 10320
ATP2B1 10300
CD9 10281
GNGT2 10236
MICAL1 10205
SLC7A9 10188
CSK 10156

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
VPREB3 10789.0
GNB3 10775.0
CEACAM1 10746.0
ORM2 10683.0
TUBA3D 10642.0
GP1BB 10640.0
LCK 10594.0
IFNB1 10578.0
SLC7A5 10514.0
PSG11 10453.0
SERPINB2 10365.0
MAFF 10364.0
VPREB1 10351.0
SERPINA4 10320.0
ATP2B1 10300.0
CD9 10281.0
GNGT2 10236.0
MICAL1 10205.0
SLC7A9 10188.0
CSK 10156.0
ATP2A3 10152.0
KIF4B 10144.0
RAC2 10136.0
ISLR 10114.0
GNAS 10091.0
SLC16A3 10062.0
IFNA6 9955.0
KIF2A 9935.0
TUBA3C 9921.0
FCER1G 9858.0
PSG7 9786.0
HGF 9684.0
F11 9518.0
KIF5A 9473.0
PDPK1 9459.0
DOK2 9391.0
SLC7A8 9371.0
ITIH3 9353.0
ACTN1 9315.0
VEGFB 9311.0
DGKD 9193.0
TF 9166.0
PIK3R6 9156.0
ITGB2 9130.0
ITGAL 9076.0
APOA1 9038.0
ITGAX 9017.0
RHOB 8992.0
H3C7 8981.5
LRP8 8930.0
H3C3 8927.0
ANGPT4 8908.0
FGG 8841.0
CTSW 8814.0
TLN1 8790.0
SERPINC1 8782.0
TUBB6 8755.0
A1BG 8721.0
PRKCQ 8542.0
P2RY12 8469.0
KIF1C 8467.0
PSAP 8462.0
DGKZ 8435.0
EHD3 8413.0
TNFRSF10A 8400.0
CYRIB 8398.0
KIF21B 8377.0
SLC16A8 8358.0
PIK3R1 8263.0
CLEC1B 8212.0
ZFPM1 8193.0
KLKB1 8125.0
RAC1 8122.0
ITPK1 8107.0
MAG 8105.0
HBG2 8098.0
PPIL2 8071.0
HBD 8070.0
KLC3 8037.0
SRC 8026.0
CD84 8011.0
INPP5D 7921.0
PRKCH 7881.0
TUBB1 7829.0
QSOX1 7762.0
F11R 7755.0
JCHAIN 7699.0
EPCAM 7685.0
GNG4 7647.0
SYK 7645.0
SLC7A11 7642.0
PSG4 7595.0
PROC 7556.0
S100A10 7489.0
ACTN4 7487.0
LGALS3BP 7471.0
KNG1 7465.0
HBB 7464.0
PIK3R5 7450.0
CD48 7431.0
EHD1 7429.0
MAFK 7395.0
PPBP 7394.0
SH2B2 7378.0
PLG 7357.0
AKT1 7231.0
PCYOX1L 7224.0
RASGRP1 7200.0
ITIH4 7195.0
FCAMR 7133.0
PPP2R1B 7101.0
ABHD12 6985.0
TGFB3 6943.0
FGB 6886.0
GNG12 6873.0
AKAP1 6829.0
ITGA6 6810.0
LYN 6800.0
TUBA8 6777.0
TNFRSF10B 6740.0
APLP2 6729.0
JAM3 6700.0
STXBP2 6690.0
GPC1 6657.0
VAV2 6650.0
SELE 6618.0
CEACAM8 6614.0
TAGLN2 6601.0
DGKA 6600.0
PPP2CB 6598.0
KLC1 6522.0
COL1A1 6443.0
ITGA5 6432.0
SLC7A7 6403.0
F7 6378.0
PTPN6 6359.0
PRKCD 6332.0
BSG 6314.0
KLC2 6309.0
ORAI2 6296.0
ATP1B2 6283.0
MERTK 6216.0
GRB7 6212.0
SLC7A6 6208.0
CAPZB 6165.0
CDC42 6139.0
CABLES2 6108.0
P2RX1 6100.0
GNAI2 6080.0
ATP1B1 6070.0
RAF1 6019.0
DOCK8 5975.0
DOCK10 5883.0
PIK3R2 5878.0
MGLL 5816.0
APBB1IP 5806.0
PDE1B 5665.0
ACTN2 5616.0
ADRA2C 5570.0
BRPF3 5546.0
CHID1 5539.0
DOCK2 5516.0
PLCG2 5491.0
GNAI1 5459.0
KIF27 5443.0
TGFB2 5394.0
TEX264 5385.0
ITGA4 5316.0
TP53 5315.0
SDC1 5314.0
F10 5281.0
HDAC1 5175.0
TUBB2B 5110.0
HDAC2 5095.0
KIF13B 5068.0
EHD2 5059.0
NRAS 5054.0
SDC3 4982.0
A2M 4959.0
PDE9A 4948.0
P2RX5 4936.0
TUBA1C 4895.0
GATA5 4893.0
ABL1 4846.0
SERPINB6 4843.0
DAGLB 4783.0
GNG7 4722.0
DOCK5 4718.0
CRK 4716.0
MFN2 4639.0
PTPN1 4415.0
MAPK1 4404.0
ITPR2 4400.0
TREM1 4372.0
F2R 4344.0
GNG2 4324.0
ANGPT1 4312.0
STIM1 4271.0
FGR 4264.0
KIF20B 4174.0
FYN 4117.0
MPIG6B 4081.0
CD44 4044.0
PDE5A 4030.0
TUBA1A 4010.0
JAML 4008.0
ATP2B4 3981.0
PSG5 3965.0
GUCY1A1 3942.0
SERPINE2 3938.0
PLAT 3926.0
GNB1 3921.0
PPP2R5A 3918.0
PPP2R5C 3911.0
PRKAR1A 3893.0
SIRPG 3889.0
PECAM1 3840.0
ITPR3 3822.0
H3-3B 3816.0
IRF2 3807.0
GP9 3767.0
RASGRP2 3748.0
RAD51B 3739.0
MAPK3 3720.0
GNA14 3646.0
GYPA 3612.0
ARRB1 3591.0
RARRES2 3584.0
RAP1A 3553.0
PRKCA 3441.0
PDGFA 3410.0
ADRA2B 3365.0
PHF21A 3347.0
MFN1 3328.0
LCP2 3293.0
SIRPA 3177.0
DGKQ 3144.0
DOCK3 3007.0
PLA2G4A 3000.0
HRG 2939.0
CFL1 2933.0
CEACAM5 2909.0
IFNA5 2890.0
PRKACA 2802.0
PROS1 2798.0
PRKAR1B 2707.0
P2RX4 2618.0
PDE11A 2429.0
DGKH 2427.0
GYPC 2413.0
VEGFC 2405.0
SERPING1 2347.0
KIF22 2318.0
ITGAV 2311.0
DGKE 2167.0
EGF 2164.0
KIF1A 2140.0
STXBP3 2136.0
SCCPDH 2090.0
ITGB1 2034.0
HMG20B 1993.0
PRKCB 1981.0
ITPR1 1953.0
KDM1A 1949.0
ITGA2 1940.0
TOR4A 1928.0
SERPINA1 1923.0
ITGA2B 1909.0
TNFRSF10D 1887.0
JMJD1C 1833.0
KCNMB1 1808.0
KIF26B 1548.0
GNA15 1546.0
DGKG 1449.0
VPS45 1406.0
PTGIR 1388.0
GNB5 1330.0
IRAG1 1307.0
RAPGEF3 1288.0
KIF21A 1232.0
TUBA4A 1191.0
ATP2A1 1187.0
P2RY1 1171.0
VWF 1155.0
DOCK4 1148.0
VCL 1081.0
TGFB1 1028.0
IGF2 1002.0
DOCK7 983.0
PIK3CB 975.0
DGKI 864.0
TRPC6 840.0
ECM1 835.0
APP 815.0
FAM3C 812.0
SRI 808.0
ABHD6 796.0
SLC16A1 792.0
PPP2R5E 784.0
TUBB4B 746.0
SLC8A3 732.0
GNB4 731.0
CD47 722.0
KRAS 718.0
PLAU 660.0
CD36 618.0
CARMIL1 595.0
DOCK1 571.0
NHLRC2 569.0
BCAR1 510.0
ITGB3 470.0
KIF5B 459.0
PPP2R5B 439.0
GNAQ 436.0
GATA4 432.0
P2RX7 427.0
TBXA2R 391.0
LEFTY2 372.0
ZFPM2 323.0
TRPC7 244.0
PLCG1 233.0
GRB2 152.0
P2RX3 92.0
GNA12 71.0
PROCR -12.0
KIF20A -44.0
MAPK14 -47.0
SLC8A1 -63.0
KIF1B -75.0
PRKAR2B -205.0
ITGA10 -226.0
PRKCE -277.0
H3C6 -336.0
CD109 -393.0
JAM2 -399.0
ESAM -413.0
KIF9 -430.0
PRKAR2A -455.0
CD2 -456.0
FN1 -458.0
CDC37L1 -466.0
CAPZA2 -468.0
GATA6 -488.0
SPARC -539.0
RAP1B -559.0
GNA11 -655.0
KCNMB2 -672.0
ACTB -701.0
PCDH7 -743.0
LY6G6F -748.0
KIF16B -785.0
DAGLA -797.0
KIF6 -800.0
VAV3 -820.0
SH2B1 -879.0
PTPN11 -957.0
PHACTR2 -968.0
PRKACG -999.0
PRTN3 -1054.0
SOS1 -1066.0
THPO -1092.0
SERPINB8 -1125.0
CALM1 -1130.0
PRCP -1334.0
APOB -1362.0
CXADR -1364.0
GNG13 -1387.0
THBS1 -1415.0
RAPGEF4 -1422.0
ATP2B2 -1443.0
NOS3 -1459.0
RAB5A -1468.0
ORAI1 -1548.0
C1QBP -1647.0
GTPBP2 -1703.0
PLEK -1710.0
GNG11 -1757.0
SERPINA5 -1795.0
SLC8A2 -1856.0
F2RL2 -1888.0
PRKCZ -1979.0
SIN3A -1989.0
GP6 -2005.0
AKAP10 -2025.0
KIF26A -2063.0
PF4 -2109.0
ADRA2A -2113.0
SPP2 -2129.0
F2 -2224.0
H3C8 -2242.0
FERMT3 -2255.0
DOCK6 -2287.0
PTK2 -2288.0
CBX5 -2314.0
TUBB8 -2320.0
OLA1 -2335.0
CABLES1 -2415.0
CD63 -2428.0
DOCK9 -2439.0
ABCC4 -2467.0
VAV1 -2494.0
GP5 -2529.0
CDK2 -2539.0
GNG5 -2583.0
F13A1 -2645.0
HSPA5 -2669.0
HRAS -2839.0
PIK3CG -2882.0
TTN -2899.0
GLG1 -2923.0
P2RX2 -2930.0
IFNA13 -2934.0
WDR1 -2959.0
SLC7A10 -3003.0
ALDOA -3097.0
ATP1B3 -3111.0
H3C12 -3194.0
IGF1 -3226.0
JAK2 -3310.0
NOS1 -3311.0
GUCY1A2 -3334.0
LAT -3349.0
KIF3B -3418.0
ITGA3 -3429.0
SDC2 -3458.0
KIFC1 -3486.0
KCNMB3 -3511.0
ANXA2 -3552.0
RACGAP1 -3568.0
CLU -3582.0
PIK3R3 -3645.0
ARRB2 -3663.0
PFN1 -3702.0
F3 -3722.0
TEK -3855.0
CD74 -3944.0
STX4 -4002.0
HABP4 -4003.0
RCOR1 -4047.0
YWHAZ -4048.0
PRKG1 -4069.0
VTI1B -4110.0
MYB -4215.0
P2RX6 -4231.0
SERPINE1 -4233.0
YES1 -4284.0
RBSN -4322.0
CD177 -4397.0
IFNA16 -4428.0
IRF1 -4439.0
GNAT3 -4448.0
RAB27B -4508.0
SELP -4510.0
FGA -4581.0
H3C1 -4612.0
H3C11 -4615.0
KCNMA1 -4621.0
PDE2A -4673.0
ANGPT2 -4730.0
KIF18A -4735.0
PRKACB -4770.0
KIF2C -4885.0
CAP1 -4918.0
KIF2B -4931.0
F2RL3 -5009.0
SCG3 -5035.0
LHFPL2 -5082.0
PPP2R1A -5096.0
MPL -5144.0
TMX3 -5156.0
KIFAP3 -5216.0
F5 -5273.0
CAPZA1 -5334.0
CYB5R1 -5455.0
CD244 -5497.0
GNG3 -5571.0
PIK3CA -5583.0
SH2B3 -5601.0
THBD -5702.0
RHOA -5826.0
KIFC2 -5855.0
NFE2 -5860.0
KIF11 -5887.0
PPP2R5D -5910.0
KIF25 -5961.0
KIF15 -5974.0
TUBA4B -5985.0
TRPC3 -6012.0
MMRN1 -6056.0
CALU -6058.0
PDPN -6071.0
GATA3 -6114.0
KIF23 -6115.0
GNG10 -6129.0
MMP1 -6319.0
TUBB2A -6353.0
ANXA5 -6470.0
PDGFB -6533.0
H3C2 -6560.0
AHSG -6575.0
SRGN -6579.0
ALB -6630.0
RHOG -6637.0
AAMP -6675.0
ITGA1 -6737.0
GNB2 -6742.0
PPIA -6821.0
CAV1 -6823.0
HBG1 -6847.0
H3-3A -6960.0
COL1A2 -7059.0
PDE10A -7111.0
PPP2CA -7146.0
F13B -7217.0
TUBB3 -7345.0
KLC4 -7433.0
GNAI3 -7543.0
PLAUR -7574.0
MIF -7597.0
SOD1 -7677.0
PRKCG -7785.0
IFNA8 -7791.0
KIF18B -7838.0
CD58 -7865.0
CFD -8023.0
GUCY1B1 -8074.0
DGKB -8102.0
TUBA3E -8172.0
GNGT1 -8192.0
MAFG -8254.0
WEE1 -8318.0
OLR1 -8347.0
SERPINF2 -8447.0
PRKG2 -8454.0
SELL -8457.0
GRB14 -8489.0
CENPE -8497.0
TUBB4A -8498.0
CDK5 -8579.0
GNA13 -8637.0
KIF19 -8707.0
SLC3A2 -8747.0
GNG8 -8827.0
NOS2 -8894.0
KIF3A -9033.0
IFNA2 -9041.0
H3C4 -9046.0
SDC4 -9074.0
APOH -9089.0
VEGFA -9097.0
PF4V1 -9126.0
PSG1 -9142.0
SERPINA3 -9207.0
PICK1 -9271.0
MANF -9299.0
KIF3C -9333.0
AK3 -9343.0
PAFAH2 -9368.0
H3C10 -9400.0
CEACAM6 -9432.0
TUBA1B -9443.0
ATP2A2 -9515.0
TIMP3 -9519.0
GATA2 -9618.0
ENDOD1 -9647.0
F12 -9722.0
KIF12 -9857.0
PDE1A -9872.0
ORM1 -9881.0
SHC1 -9953.0
SELPLG -10009.0
IFNA14 -10046.0
PSG2 -10087.0
SPN -10090.0
TFPI -10143.0
KCNMB4 -10173.0
TUBAL3 -10277.0
PSG9 -10286.0
RAD51C -10289.0
CLEC3B -10361.0
SERPIND1 -10478.0
SELENOP -10542.0
HBE1 -10715.0
ITGAM -10716.0
GP1BA -10752.0
IFNA1 -10778.0
IFNA7 -10834.0
IFNA21 -10838.0
IGLL1 -10889.0
PSG8 -10913.0
CEACAM3 -10970.0


REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES

REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES
50
set REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES
setSize 80
pANOVA 0.00308
s.dist -0.191
p.adjustANOVA 0.101



Top enriched genes

Top 20 genes
GeneID Gene Rank
KPNA7 -10650
ISG15 -9963
EIF4A2 -9888
POM121 -9356
IFIT1 -8888
POM121C -8815
USP18 -8617
SEH1L -8298
IRF3 -8235
KPNB1 -8106
HERC5 -8065
OAS3 -7937
RIGI -7847
NUP155 -7766
EIF4E2 -7601
KPNA2 -7242
OASL -6929
NUP58 -6850
UBA52 -6801
NUP54 -6598

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
KPNA7 -10650
ISG15 -9963
EIF4A2 -9888
POM121 -9356
IFIT1 -8888
POM121C -8815
USP18 -8617
SEH1L -8298
IRF3 -8235
KPNB1 -8106
HERC5 -8065
OAS3 -7937
RIGI -7847
NUP155 -7766
EIF4E2 -7601
KPNA2 -7242
OASL -6929
NUP58 -6850
UBA52 -6801
NUP54 -6598
UBC -6316
UBE2L6 -6214
PDE12 -6182
RNASEL -6175
PPM1B -6075
EIF4G2 -6037
OAS1 -5984
SEC13 -5971
NUP43 -5857
NUP37 -5559
EIF4A3 -5476
ARIH1 -5242
RPS27A -5186
NUP153 -4963
UBE2N -4353
NDC1 -4338
TRIM25 -3912
NEDD4 -3597
EIF4A1 -3505
TPR -3264
KPNA1 -3170
ABCE1 -2802
EIF4G3 -2454
RANBP2 -2371
KPNA5 -2326
EIF4G1 -2048
UBE2E1 -1821
NUP98 -1787
NUP42 -1540
NUP214 -322
EIF2AK2 -283
NUP88 31
PLCG1 233
NUP160 766
KPNA3 896
NUP50 1298
EIF4E 1594
NUP107 1840
STAT1 1869
EIF4E3 1936
UBA7 2404
NUP85 2441
NUP205 3348
NUP62 3360
MAPK3 3720
NUP93 3792
KPNA4 3953
NUP133 4054
MX2 4096
UBB 4462
PIN1 4691
AAAS 5713
RAE1 5767
NUP188 5843
NUP35 6436
FLNB 6746
MX1 6827
OAS2 7754
NUP210 9050
JAK1 9739


Here is the session info with all the versions of packages used.

sessionInfo()
## R version 4.3.2 (2023-10-31)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.3 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3 
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so;  LAPACK version 3.10.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Etc/UTC
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.3.3                                      
##  [2] GGally_2.2.0                                       
##  [3] ggplot2_3.4.4                                      
##  [4] reshape2_1.4.4                                     
##  [5] gtools_3.9.5                                       
##  [6] tibble_3.2.1                                       
##  [7] dplyr_1.1.4                                        
##  [8] echarts4r_0.4.5                                    
##  [9] png_0.1-8                                          
## [10] gridExtra_2.3                                      
## [11] missMethyl_1.36.0                                  
## [12] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.1 
## [13] beeswarm_0.4.0                                     
## [14] kableExtra_1.3.4                                   
## [15] gplots_3.1.3                                       
## [16] mitch_1.15.0                                       
## [17] tictoc_1.2                                         
## [18] HGNChelper_0.8.1                                   
## [19] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [20] IlluminaHumanMethylation450kmanifest_0.4.0         
## [21] minfi_1.48.0                                       
## [22] bumphunter_1.44.0                                  
## [23] locfit_1.5-9.8                                     
## [24] iterators_1.0.14                                   
## [25] foreach_1.5.2                                      
## [26] Biostrings_2.70.1                                  
## [27] XVector_0.42.0                                     
## [28] SummarizedExperiment_1.32.0                        
## [29] Biobase_2.62.0                                     
## [30] MatrixGenerics_1.14.0                              
## [31] matrixStats_1.2.0                                  
## [32] GenomicRanges_1.54.1                               
## [33] GenomeInfoDb_1.38.2                                
## [34] IRanges_2.36.0                                     
## [35] S4Vectors_0.40.2                                   
## [36] BiocGenerics_0.48.1                                
## [37] eulerr_7.0.0                                       
## [38] limma_3.58.1                                       
## 
## loaded via a namespace (and not attached):
##   [1] splines_4.3.2             later_1.3.2              
##   [3] BiocIO_1.12.0             bitops_1.0-7             
##   [5] filelock_1.0.3            preprocessCore_1.64.0    
##   [7] XML_3.99-0.16             lifecycle_1.0.4          
##   [9] lattice_0.22-5            MASS_7.3-60              
##  [11] base64_2.0.1              scrime_1.3.5             
##  [13] magrittr_2.0.3            sass_0.4.8               
##  [15] rmarkdown_2.25            jquerylib_0.1.4          
##  [17] yaml_2.3.8                httpuv_1.6.13            
##  [19] doRNG_1.8.6               askpass_1.2.0            
##  [21] DBI_1.1.3                 RColorBrewer_1.1-3       
##  [23] abind_1.4-5               zlibbioc_1.48.0          
##  [25] rvest_1.0.3               quadprog_1.5-8           
##  [27] purrr_1.0.2               RCurl_1.98-1.13          
##  [29] rappdirs_0.3.3            GenomeInfoDbData_1.2.11  
##  [31] genefilter_1.84.0         annotate_1.80.0          
##  [33] svglite_2.1.3             DelayedMatrixStats_1.24.0
##  [35] codetools_0.2-19          DelayedArray_0.28.0      
##  [37] xml2_1.3.6                tidyselect_1.2.0         
##  [39] beanplot_1.3.1            BiocFileCache_2.10.1     
##  [41] webshot_0.5.5             illuminaio_0.44.0        
##  [43] GenomicAlignments_1.38.0  jsonlite_1.8.8           
##  [45] multtest_2.58.0           ellipsis_0.3.2           
##  [47] survival_3.5-7            systemfonts_1.0.5        
##  [49] tools_4.3.2               progress_1.2.3           
##  [51] Rcpp_1.0.11               glue_1.6.2               
##  [53] SparseArray_1.2.2         xfun_0.41                
##  [55] HDF5Array_1.30.0          withr_2.5.2              
##  [57] fastmap_1.1.1             rhdf5filters_1.14.1      
##  [59] fansi_1.0.6               openssl_2.1.1            
##  [61] caTools_1.18.2            digest_0.6.33            
##  [63] R6_2.5.1                  mime_0.12                
##  [65] colorspace_2.1-0          biomaRt_2.58.0           
##  [67] RSQLite_2.3.4             utf8_1.2.4               
##  [69] tidyr_1.3.0               generics_0.1.3           
##  [71] data.table_1.14.10        rtracklayer_1.62.0       
##  [73] prettyunits_1.2.0         httr_1.4.7               
##  [75] htmlwidgets_1.6.4         S4Arrays_1.2.0           
##  [77] ggstats_0.5.1             pkgconfig_2.0.3          
##  [79] gtable_0.3.4              blob_1.2.4               
##  [81] siggenes_1.76.0           htmltools_0.5.7          
##  [83] scales_1.3.0              rstudioapi_0.15.0        
##  [85] knitr_1.45                tzdb_0.4.0               
##  [87] rjson_0.2.21              nlme_3.1-163             
##  [89] curl_5.2.0                org.Hs.eg.db_3.18.0      
##  [91] cachem_1.0.8              rhdf5_2.46.1             
##  [93] stringr_1.5.1             KernSmooth_2.23-22       
##  [95] AnnotationDbi_1.64.1      restfulr_0.0.15          
##  [97] GEOquery_2.70.0           pillar_1.9.0             
##  [99] grid_4.3.2                reshape_0.8.9            
## [101] vctrs_0.6.5               promises_1.2.1           
## [103] dbplyr_2.4.0              xtable_1.8-4             
## [105] evaluate_0.23             readr_2.1.4              
## [107] GenomicFeatures_1.54.1    cli_3.6.2                
## [109] compiler_4.3.2            Rsamtools_2.18.0         
## [111] rlang_1.1.2               crayon_1.5.2             
## [113] rngtools_1.5.2            nor1mix_1.3-2            
## [115] mclust_6.0.1              plyr_1.8.9               
## [117] stringi_1.8.3             viridisLite_0.4.2        
## [119] BiocParallel_1.36.0       munsell_0.5.0            
## [121] Matrix_1.6-1.1            hms_1.1.3                
## [123] sparseMatrixStats_1.14.0  bit64_4.0.5              
## [125] Rhdf5lib_1.24.1           KEGGREST_1.42.0          
## [127] statmod_1.5.0             shiny_1.8.0              
## [129] highr_0.10                memoise_2.0.1            
## [131] bslib_0.6.1               bit_4.0.5

END of report