date generated: 2024-01-18

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch
x
A1BG 0.0033540
A1BG-AS1 -0.0014041
A1CF 0.0007266
A2M -0.0046554
A2M-AS1 0.0019842
A2ML1 -0.0002314

Here are some metrics about the input data profile:

Profiling data metrics
Profile metrics
num_genesets 1654
num_genes_in_profile 22007
duplicated_genes_present 0
num_profile_genes_in_sets 10383
num_profile_genes_not_in_sets 11624

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets: c2.cp.reactome.v2023.1.Hs.symbols.gmt
Gene set metrics
Gene sets metrics
num_genesets 1654
num_genesets_excluded 365
num_genesets_included 1289

Differential pathway expression


Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

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## in kable. kableExtra can customize either HTML or LaTeX outputs. See
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set setSize pANOVA s.dist p.adjustANOVA
REACTOME METABOLISM OF RNA 675 1.72e-17 0.1920 2.83e-14
REACTOME TRANSLATION 278 2.28e-15 0.2760 1.87e-12
REACTOME CELL CYCLE 666 3.70e-11 0.1500 2.02e-08
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY 94 7.87e-11 0.3880 2.96e-08
REACTOME EUKARYOTIC TRANSLATION INITIATION 110 9.02e-11 0.3580 2.96e-08
REACTOME CELLULAR RESPONSES TO STIMULI 779 4.02e-10 0.1320 9.42e-08
REACTOME INFLUENZA INFECTION 149 4.02e-10 0.2970 9.42e-08
REACTOME INFECTIOUS DISEASE 910 6.72e-10 0.1210 1.38e-07
REACTOME NONSENSE MEDIATED DECAY NMD 107 2.44e-09 0.3340 4.42e-07
REACTOME EUKARYOTIC TRANSLATION ELONGATION 87 2.69e-09 0.3690 4.42e-07
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS 161 3.93e-09 0.2690 5.45e-07
REACTOME CELL CYCLE MITOTIC 539 3.98e-09 0.1480 5.45e-07
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE 105 7.43e-09 0.3260 9.38e-07
REACTOME RNA POLYMERASE II TRANSCRIPTION 1336 9.83e-09 0.0934 1.15e-06
REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY 46 2.12e-08 0.4770 2.32e-06
REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 100 2.76e-08 0.3210 2.83e-06
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA 263 4.03e-08 0.1970 3.90e-06
REACTOME DNA REPLICATION PRE INITIATION 150 5.33e-08 0.2570 4.86e-06
REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3 59 6.27e-08 0.4070 5.42e-06
REACTOME DNA REPLICATION 178 7.81e-08 0.2330 6.26e-06
REACTOME M PHASE 398 8.00e-08 0.1570 6.26e-06
REACTOME CELLULAR RESPONSE TO STARVATION 147 1.01e-07 0.2540 7.51e-06
REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION 84 1.12e-07 0.3350 7.82e-06
REACTOME MITOCHONDRIAL TRANSLATION 93 1.14e-07 0.3180 7.82e-06
REACTOME SIGNALING BY ROBO RECEPTORS 206 1.92e-07 0.2100 1.26e-05
REACTOME MEIOTIC RECOMBINATION 80 2.02e-07 0.3360 1.27e-05
REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION 60 2.39e-07 0.3860 1.45e-05
REACTOME CELL CYCLE CHECKPOINTS 284 2.70e-07 0.1770 1.58e-05
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION 138 3.38e-07 0.2510 1.88e-05
REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 98 3.43e-07 0.2980 1.88e-05
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS 121 3.99e-07 0.2670 2.11e-05
REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION 62 6.52e-07 0.3650 3.34e-05
REACTOME RRNA PROCESSING 192 9.29e-07 0.2050 4.62e-05
REACTOME DNA METHYLATION 58 9.88e-07 0.3710 4.77e-05
REACTOME RHO GTPASES ACTIVATE PKNS 86 1.02e-06 0.3050 4.80e-05
REACTOME SARS COV 1 HOST INTERACTIONS 92 1.10e-06 0.2940 5.01e-05
REACTOME SENSORY PERCEPTION 555 1.17e-06 -0.1210 5.18e-05
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY 33 1.30e-06 0.4870 5.60e-05
REACTOME RHO GTPASE EFFECTORS 305 1.54e-06 0.1600 6.48e-05
REACTOME DISEASES OF PROGRAMMED CELL DEATH 96 1.66e-06 0.2830 6.80e-05
REACTOME RNA POLYMERASE I PROMOTER ESCAPE 83 1.73e-06 0.3040 6.92e-05
REACTOME EXTRACELLULAR MATRIX ORGANIZATION 291 1.97e-06 -0.1620 7.72e-05
REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS 83 2.08e-06 0.3010 7.96e-05
REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION 68 2.86e-06 0.3280 1.07e-04
REACTOME MRNA SPLICING 197 3.77e-06 0.1910 1.38e-04
REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP 104 3.96e-06 0.2620 1.41e-04
REACTOME SELENOAMINO ACID METABOLISM 108 5.14e-06 0.2540 1.80e-04
REACTOME CONDENSATION OF PROPHASE CHROMOSOMES 66 5.41e-06 0.3240 1.85e-04
REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS 113 5.90e-06 0.2470 1.97e-04
REACTOME DEUBIQUITINATION 260 5.99e-06 0.1630 1.97e-04


Results (complete table)


Click HERE to show results for all gene sets

Complete results
set setSize pANOVA s.dist p.adjustANOVA
REACTOME METABOLISM OF RNA 675 1.72e-17 1.92e-01 2.83e-14
REACTOME TRANSLATION 278 2.28e-15 2.76e-01 1.87e-12
REACTOME CELL CYCLE 666 3.70e-11 1.50e-01 2.02e-08
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY 94 7.87e-11 3.88e-01 2.96e-08
REACTOME EUKARYOTIC TRANSLATION INITIATION 110 9.02e-11 3.58e-01 2.96e-08
REACTOME CELLULAR RESPONSES TO STIMULI 779 4.02e-10 1.32e-01 9.42e-08
REACTOME INFLUENZA INFECTION 149 4.02e-10 2.97e-01 9.42e-08
REACTOME INFECTIOUS DISEASE 910 6.72e-10 1.21e-01 1.38e-07
REACTOME NONSENSE MEDIATED DECAY NMD 107 2.44e-09 3.34e-01 4.42e-07
REACTOME EUKARYOTIC TRANSLATION ELONGATION 87 2.69e-09 3.69e-01 4.42e-07
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS 161 3.93e-09 2.69e-01 5.45e-07
REACTOME CELL CYCLE MITOTIC 539 3.98e-09 1.48e-01 5.45e-07
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE 105 7.43e-09 3.26e-01 9.38e-07
REACTOME RNA POLYMERASE II TRANSCRIPTION 1336 9.83e-09 9.34e-02 1.15e-06
REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY 46 2.12e-08 4.77e-01 2.32e-06
REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 100 2.76e-08 3.21e-01 2.83e-06
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA 263 4.03e-08 1.97e-01 3.90e-06
REACTOME DNA REPLICATION PRE INITIATION 150 5.33e-08 2.57e-01 4.86e-06
REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3 59 6.27e-08 4.07e-01 5.42e-06
REACTOME DNA REPLICATION 178 7.81e-08 2.33e-01 6.26e-06
REACTOME M PHASE 398 8.00e-08 1.57e-01 6.26e-06
REACTOME CELLULAR RESPONSE TO STARVATION 147 1.01e-07 2.54e-01 7.51e-06
REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION 84 1.12e-07 3.35e-01 7.82e-06
REACTOME MITOCHONDRIAL TRANSLATION 93 1.14e-07 3.18e-01 7.82e-06
REACTOME SIGNALING BY ROBO RECEPTORS 206 1.92e-07 2.10e-01 1.26e-05
REACTOME MEIOTIC RECOMBINATION 80 2.02e-07 3.36e-01 1.27e-05
REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION 60 2.39e-07 3.86e-01 1.45e-05
REACTOME CELL CYCLE CHECKPOINTS 284 2.70e-07 1.77e-01 1.58e-05
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION 138 3.38e-07 2.51e-01 1.88e-05
REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 98 3.43e-07 2.98e-01 1.88e-05
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS 121 3.99e-07 2.67e-01 2.11e-05
REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION 62 6.52e-07 3.65e-01 3.34e-05
REACTOME RRNA PROCESSING 192 9.29e-07 2.05e-01 4.62e-05
REACTOME DNA METHYLATION 58 9.88e-07 3.71e-01 4.77e-05
REACTOME RHO GTPASES ACTIVATE PKNS 86 1.02e-06 3.05e-01 4.80e-05
REACTOME SARS COV 1 HOST INTERACTIONS 92 1.10e-06 2.94e-01 5.01e-05
REACTOME SENSORY PERCEPTION 555 1.17e-06 -1.21e-01 5.18e-05
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY 33 1.30e-06 4.87e-01 5.60e-05
REACTOME RHO GTPASE EFFECTORS 305 1.54e-06 1.60e-01 6.48e-05
REACTOME DISEASES OF PROGRAMMED CELL DEATH 96 1.66e-06 2.83e-01 6.80e-05
REACTOME RNA POLYMERASE I PROMOTER ESCAPE 83 1.73e-06 3.04e-01 6.92e-05
REACTOME EXTRACELLULAR MATRIX ORGANIZATION 291 1.97e-06 -1.62e-01 7.72e-05
REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS 83 2.08e-06 3.01e-01 7.96e-05
REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION 68 2.86e-06 3.28e-01 1.07e-04
REACTOME MRNA SPLICING 197 3.77e-06 1.91e-01 1.38e-04
REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP 104 3.96e-06 2.62e-01 1.41e-04
REACTOME SELENOAMINO ACID METABOLISM 108 5.14e-06 2.54e-01 1.80e-04
REACTOME CONDENSATION OF PROPHASE CHROMOSOMES 66 5.41e-06 3.24e-01 1.85e-04
REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS 113 5.90e-06 2.47e-01 1.97e-04
REACTOME DEUBIQUITINATION 260 5.99e-06 1.63e-01 1.97e-04
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S 53 6.28e-06 3.59e-01 2.02e-04
REACTOME RNA POLYMERASE I TRANSCRIPTION 102 8.61e-06 2.55e-01 2.72e-04
REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS 100 9.28e-06 2.56e-01 2.87e-04
REACTOME UB SPECIFIC PROCESSING PROTEASES 187 9.66e-06 1.88e-01 2.94e-04
REACTOME NGF STIMULATED TRANSCRIPTION 38 1.46e-05 4.06e-01 4.35e-04
REACTOME REPRODUCTION 136 1.95e-05 2.12e-01 5.71e-04
REACTOME MEIOSIS 110 2.41e-05 2.33e-01 6.94e-04
REACTOME PRC2 METHYLATES HISTONES AND DNA 65 3.12e-05 2.99e-01 8.82e-04
REACTOME SARS COV 1 INFECTION 136 3.20e-05 2.07e-01 8.89e-04
REACTOME MITOTIC PROPHASE 134 3.74e-05 2.06e-01 1.02e-03
REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX 134 4.69e-05 -2.04e-01 1.26e-03
REACTOME HCMV LATE EVENTS 110 5.05e-05 2.24e-01 1.34e-03
REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX 85 5.20e-05 2.54e-01 1.35e-03
REACTOME CHROMOSOME MAINTENANCE 130 5.40e-05 2.05e-01 1.38e-03
REACTOME AMYLOID FIBER FORMATION 102 5.51e-05 2.31e-01 1.39e-03
REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES 353 5.83e-05 1.25e-01 1.44e-03
REACTOME G2 M CHECKPOINTS 162 5.89e-05 1.83e-01 1.44e-03
REACTOME DNA REPAIR 321 7.08e-05 1.29e-01 1.71e-03
REACTOME UCH PROTEINASES 99 7.32e-05 2.31e-01 1.72e-03
REACTOME HDACS DEACETYLATE HISTONES 85 7.32e-05 2.49e-01 1.72e-03
REACTOME SIGNALING BY NOTCH 234 1.07e-04 1.47e-01 2.47e-03
REACTOME NEDDYLATION 235 1.11e-04 1.46e-01 2.54e-03
REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE 66 1.13e-04 2.75e-01 2.55e-03
REACTOME OLFACTORY SIGNALING PATHWAY 348 1.45e-04 -1.19e-01 3.22e-03
REACTOME SARS COV 2 HOST INTERACTIONS 191 1.60e-04 1.58e-01 3.51e-03
REACTOME SARS COV INFECTIONS 392 1.67e-04 1.11e-01 3.60e-03
REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE 63 1.69e-04 2.74e-01 3.60e-03
REACTOME CELLULAR SENESCENCE 189 1.82e-04 1.58e-01 3.82e-03
REACTOME HCMV EARLY EVENTS 128 1.85e-04 1.91e-01 3.85e-03
REACTOME PROTEIN LOCALIZATION 153 2.37e-04 1.72e-01 4.85e-03
REACTOME HCMV INFECTION 152 2.78e-04 1.71e-01 5.64e-03
REACTOME MITOCHONDRIAL PROTEIN IMPORT 58 3.01e-04 2.74e-01 5.97e-03
REACTOME SEPARATION OF SISTER CHROMATIDS 184 3.02e-04 1.54e-01 5.97e-03
REACTOME MUSCLE CONTRACTION 197 3.78e-04 -1.47e-01 7.34e-03
REACTOME TELOMERE MAINTENANCE 106 3.80e-04 2.00e-01 7.34e-03
REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS 111 5.70e-04 1.89e-01 1.09e-02
REACTOME MRNA SPLICING MINOR PATHWAY 49 5.79e-04 2.84e-01 1.09e-02
REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS 38 5.86e-04 3.22e-01 1.09e-02
REACTOME APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS 87 6.04e-04 2.13e-01 1.11e-02
REACTOME HATS ACETYLATE HISTONES 129 6.22e-04 1.74e-01 1.13e-02
REACTOME ESTROGEN DEPENDENT GENE EXPRESSION 140 7.15e-04 1.66e-01 1.29e-02
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM 688 7.39e-04 7.55e-02 1.32e-02
REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION 59 7.91e-04 2.53e-01 1.40e-02
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX3 94 8.01e-04 2.00e-01 1.40e-02
REACTOME MITOTIC METAPHASE AND ANAPHASE 228 8.22e-04 1.29e-01 1.42e-02
REACTOME BASE EXCISION REPAIR 87 8.74e-04 2.06e-01 1.49e-02
REACTOME SENSORY PERCEPTION OF TASTE 47 8.78e-04 -2.80e-01 1.49e-02
REACTOME FORMATION OF THE CORNIFIED ENVELOPE 125 9.08e-04 -1.72e-01 1.52e-02
REACTOME RESPIRATORY ELECTRON TRANSPORT 90 9.30e-04 2.02e-01 1.53e-02
REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION 90 9.32e-04 2.02e-01 1.53e-02
REACTOME OXIDATIVE STRESS INDUCED SENESCENCE 118 9.61e-04 1.76e-01 1.56e-02
REACTOME INTERLEUKIN 7 SIGNALING 31 9.98e-04 3.41e-01 1.61e-02
REACTOME DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE 76 1.01e-03 2.18e-01 1.61e-02
REACTOME DNA DAMAGE RECOGNITION IN GG NER 36 1.14e-03 3.13e-01 1.81e-02
REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE 52 1.17e-03 2.60e-01 1.84e-02
REACTOME MITOTIC PROMETAPHASE 194 1.21e-03 1.35e-01 1.87e-02
REACTOME PRE NOTCH EXPRESSION AND PROCESSING 112 1.22e-03 1.77e-01 1.87e-02
REACTOME BASE EXCISION REPAIR AP SITE FORMATION 59 1.33e-03 2.42e-01 2.02e-02
REACTOME GENE SILENCING BY RNA 133 1.43e-03 1.60e-01 2.15e-02
REACTOME ADAPTIVE IMMUNE SYSTEM 729 1.49e-03 6.91e-02 2.20e-02
REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21 59 1.49e-03 2.39e-01 2.20e-02
REACTOME SARS COV 2 INFECTION 281 1.50e-03 1.10e-01 2.20e-02
REACTOME SYNTHESIS OF DNA 119 1.56e-03 1.68e-01 2.26e-02
REACTOME MITOTIC G2 G2 M PHASES 194 1.58e-03 1.32e-01 2.26e-02
REACTOME HIV INFECTION 223 1.58e-03 1.23e-01 2.26e-02
REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION 145 1.70e-03 1.51e-01 2.41e-02
REACTOME MITOTIC SPINDLE CHECKPOINT 109 1.77e-03 1.73e-01 2.48e-02
REACTOME THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT 77 1.86e-03 2.05e-01 2.58e-02
REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT 222 1.87e-03 1.21e-01 2.59e-02
REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 73 1.90e-03 2.10e-01 2.60e-02
REACTOME RHO GTPASES ACTIVATE FORMINS 136 2.39e-03 1.51e-01 3.22e-02
REACTOME ECM PROTEOGLYCANS 73 2.40e-03 -2.05e-01 3.22e-02
REACTOME SCAVENGING OF HEME FROM PLASMA 13 2.45e-03 -4.85e-01 3.27e-02
REACTOME S PHASE 159 2.52e-03 1.39e-01 3.34e-02
REACTOME G2 M DNA DAMAGE CHECKPOINT 90 2.58e-03 1.84e-01 3.39e-02
REACTOME TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS 82 2.64e-03 -1.92e-01 3.42e-02
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1 229 2.65e-03 1.15e-01 3.42e-02
REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT 159 2.70e-03 1.38e-01 3.44e-02
REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION 89 2.70e-03 1.84e-01 3.44e-02
REACTOME RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY 14 2.79e-03 4.62e-01 3.52e-02
REACTOME SENSORY PERCEPTION OF SALTY TASTE 6 2.87e-03 -7.03e-01 3.59e-02
REACTOME HOST INTERACTIONS OF HIV FACTORS 127 2.91e-03 1.53e-01 3.62e-02
REACTOME ACYL CHAIN REMODELLING OF PC 27 3.04e-03 -3.29e-01 3.73e-02
REACTOME ORC1 REMOVAL FROM CHROMATIN 70 3.04e-03 2.05e-01 3.73e-02
REACTOME SNRNP ASSEMBLY 53 3.08e-03 2.35e-01 3.74e-02
REACTOME O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS 38 3.21e-03 -2.76e-01 3.87e-02
REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION 62 3.39e-03 2.15e-01 4.06e-02
REACTOME METABOLISM OF POLYAMINES 56 3.47e-03 2.26e-01 4.13e-02
REACTOME E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS 58 3.53e-03 2.21e-01 4.15e-02
REACTOME ELASTIC FIBRE FORMATION 44 3.54e-03 -2.54e-01 4.15e-02
REACTOME SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE 91 3.70e-03 1.76e-01 4.31e-02
REACTOME STABILIZATION OF P53 56 3.78e-03 2.24e-01 4.37e-02
REACTOME COLLAGEN DEGRADATION 61 3.86e-03 -2.14e-01 4.43e-02
REACTOME DEGRADATION OF GLI1 BY THE PROTEASOME 59 4.08e-03 2.16e-01 4.65e-02
REACTOME PROTEIN UBIQUITINATION 76 4.11e-03 1.90e-01 4.66e-02
REACTOME RMTS METHYLATE HISTONE ARGININES 72 4.14e-03 1.95e-01 4.66e-02
REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY 72 4.41e-03 1.94e-01 4.92e-02
REACTOME NEGATIVE REGULATION OF NOTCH4 SIGNALING 53 4.59e-03 2.25e-01 5.08e-02
REACTOME FOLDING OF ACTIN BY CCT TRIC 10 4.61e-03 5.17e-01 5.08e-02
REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES 37 4.68e-03 -2.69e-01 5.12e-02
REACTOME G1 S DNA DAMAGE CHECKPOINTS 67 4.72e-03 2.00e-01 5.13e-02
REACTOME RESOLUTION OF SISTER CHROMATID COHESION 120 5.18e-03 1.48e-01 5.60e-02
REACTOME TCR SIGNALING 113 5.88e-03 1.50e-01 6.31e-02
REACTOME CELLULAR RESPONSE TO HYPOXIA 74 5.99e-03 1.85e-01 6.39e-02
REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT 236 6.04e-03 -1.04e-01 6.40e-02
REACTOME DEVELOPMENTAL BIOLOGY 1115 6.09e-03 4.87e-02 6.41e-02
REACTOME MAPK6 MAPK4 SIGNALING 91 6.49e-03 1.65e-01 6.79e-02
REACTOME TRANSCRIPTIONAL REGULATION BY TP53 351 6.84e-03 8.40e-02 7.07e-02
REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS 5 6.85e-03 -6.98e-01 7.07e-02
REACTOME ENDOSOMAL VACUOLAR PATHWAY 11 7.01e-03 4.69e-01 7.20e-02
REACTOME SIGNALING BY NUCLEAR RECEPTORS 283 7.08e-03 9.30e-02 7.22e-02
REACTOME DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX 83 7.22e-03 1.71e-01 7.31e-02
REACTOME RECYCLING OF EIF2 GDP 7 7.29e-03 5.86e-01 7.34e-02
REACTOME NCAM1 INTERACTIONS 41 8.20e-03 -2.39e-01 8.17e-02
REACTOME INTERLEUKIN 37 SIGNALING 20 8.24e-03 -3.41e-01 8.17e-02
REACTOME ACYL CHAIN REMODELLING OF PS 22 8.26e-03 -3.25e-01 8.17e-02
REACTOME ACYL CHAIN REMODELLING OF PG 18 8.59e-03 -3.58e-01 8.43e-02
REACTOME CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY 84 8.63e-03 1.66e-01 8.43e-02
REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH 62 8.80e-03 -1.92e-01 8.55e-02
REACTOME SMOOTH MUSCLE CONTRACTION 43 8.93e-03 -2.30e-01 8.63e-02
REACTOME TNFR2 NON CANONICAL NF KB PATHWAY 96 9.00e-03 1.54e-01 8.63e-02
REACTOME PD 1 SIGNALING 21 9.04e-03 3.29e-01 8.63e-02
REACTOME PROGRAMMED CELL DEATH 204 9.12e-03 1.06e-01 8.65e-02
REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS 60 9.21e-03 1.94e-01 8.69e-02
REACTOME PROTEIN FOLDING 96 9.33e-03 1.54e-01 8.72e-02
REACTOME G ALPHA Q SIGNALLING EVENTS 206 9.35e-03 -1.05e-01 8.72e-02
REACTOME NEURONAL SYSTEM 388 1.06e-02 -7.56e-02 9.80e-02
REACTOME ADRENOCEPTORS 9 1.08e-02 4.91e-01 9.92e-02
REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS 86 1.12e-02 1.58e-01 1.03e-01
REACTOME TRNA PROCESSING IN THE NUCLEUS 58 1.13e-02 1.92e-01 1.03e-01
REACTOME SIGNALING BY NOTCH4 80 1.14e-02 1.64e-01 1.03e-01
REACTOME MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS 13 1.15e-02 4.05e-01 1.04e-01
REACTOME SUMOYLATION 179 1.16e-02 1.09e-01 1.04e-01
REACTOME REGULATION OF RUNX3 EXPRESSION AND ACTIVITY 54 1.22e-02 1.97e-01 1.09e-01
REACTOME SIGNALING BY GPCR 673 1.24e-02 -5.65e-02 1.10e-01
REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE 11 1.24e-02 -4.35e-01 1.10e-01
REACTOME AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA 54 1.32e-02 1.95e-01 1.16e-01
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL 122 1.32e-02 1.30e-01 1.16e-01
REACTOME PLATELET CALCIUM HOMEOSTASIS 27 1.35e-02 -2.75e-01 1.17e-01
REACTOME CHROMATIN MODIFYING ENZYMES 252 1.38e-02 9.01e-02 1.19e-01
REACTOME RHOQ GTPASE CYCLE 57 1.39e-02 -1.88e-01 1.19e-01
REACTOME DNA DOUBLE STRAND BREAK REPAIR 162 1.44e-02 1.11e-01 1.23e-01
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION 1356 1.47e-02 3.95e-02 1.25e-01
REACTOME REGULATED NECROSIS 57 1.51e-02 1.86e-01 1.27e-01
REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM 78 1.51e-02 1.59e-01 1.27e-01
REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX 13 1.54e-02 3.88e-01 1.29e-01
REACTOME G ALPHA I SIGNALLING EVENTS 304 1.59e-02 -8.04e-02 1.33e-01
REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION 296 1.60e-02 8.14e-02 1.33e-01
REACTOME G PROTEIN MEDIATED EVENTS 53 1.62e-02 -1.91e-01 1.34e-01
REACTOME TRANSPORT OF SMALL MOLECULES 697 1.65e-02 -5.33e-02 1.35e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX2 117 1.66e-02 1.28e-01 1.35e-01
REACTOME CYCLIN D ASSOCIATED EVENTS IN G1 46 1.67e-02 2.04e-01 1.35e-01
REACTOME RHOBTB2 GTPASE CYCLE 22 1.67e-02 2.95e-01 1.35e-01
REACTOME KERATINIZATION 210 1.69e-02 -9.57e-02 1.36e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST 18 1.72e-02 3.24e-01 1.38e-01
REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 54 1.75e-02 1.87e-01 1.39e-01
REACTOME GENERATION OF SECOND MESSENGER MOLECULES 30 1.83e-02 2.49e-01 1.45e-01
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION 361 1.85e-02 7.22e-02 1.45e-01
REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS 66 1.85e-02 -1.68e-01 1.45e-01
REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER 18 1.85e-02 3.21e-01 1.45e-01
REACTOME NONHOMOLOGOUS END JOINING NHEJ 64 1.91e-02 1.69e-01 1.48e-01
REACTOME SIGNALING BY INTERLEUKINS 444 1.91e-02 6.48e-02 1.48e-01
REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3 679 1.98e-02 5.25e-02 1.52e-01
REACTOME ION CHANNEL TRANSPORT 172 1.99e-02 -1.03e-01 1.52e-01
REACTOME INTERFERON SIGNALING 193 2.01e-02 9.70e-02 1.54e-01
REACTOME DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING 61 2.03e-02 1.72e-01 1.54e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH METHYLATION 19 2.07e-02 3.06e-01 1.57e-01
REACTOME ONCOGENE INDUCED SENESCENCE 35 2.15e-02 2.25e-01 1.62e-01
REACTOME CREB3 FACTORS ACTIVATE GENES 8 2.17e-02 4.68e-01 1.63e-01
REACTOME MEIOTIC SYNAPSIS 73 2.19e-02 1.55e-01 1.64e-01
REACTOME CARDIAC CONDUCTION 125 2.21e-02 -1.18e-01 1.65e-01
REACTOME O LINKED GLYCOSYLATION 109 2.25e-02 -1.26e-01 1.67e-01
REACTOME HEDGEHOG LIGAND BIOGENESIS 64 2.28e-02 1.65e-01 1.68e-01
REACTOME INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION 21 2.29e-02 -2.87e-01 1.68e-01
REACTOME TRNA PROCESSING 105 2.32e-02 1.28e-01 1.69e-01
REACTOME NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION 193 2.33e-02 -9.47e-02 1.69e-01
REACTOME METALLOPROTEASE DUBS 36 2.37e-02 2.18e-01 1.71e-01
REACTOME ESR MEDIATED SIGNALING 210 2.38e-02 9.05e-02 1.71e-01
REACTOME APOPTOSIS 173 2.39e-02 9.95e-02 1.72e-01
REACTOME INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING 103 2.50e-02 1.28e-01 1.78e-01
REACTOME AURKA ACTIVATION BY TPX2 69 2.51e-02 1.56e-01 1.78e-01
REACTOME ION TRANSPORT BY P TYPE ATPASES 51 2.59e-02 -1.80e-01 1.83e-01
REACTOME HDMS DEMETHYLATE HISTONES 40 2.72e-02 2.02e-01 1.92e-01
REACTOME REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION 84 2.81e-02 1.39e-01 1.97e-01
REACTOME RUNX3 REGULATES WNT SIGNALING 8 2.92e-02 4.45e-01 2.03e-01
REACTOME BINDING OF TCF LEF CTNNB1 TO TARGET GENE PROMOTERS 8 2.92e-02 4.45e-01 2.03e-01
REACTOME REGULATION OF TP53 ACTIVITY 156 2.95e-02 1.01e-01 2.04e-01
REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES 78 2.97e-02 1.42e-01 2.05e-01
REACTOME INTERLEUKIN 20 FAMILY SIGNALING 25 2.98e-02 -2.51e-01 2.05e-01
REACTOME INTERFERON ALPHA BETA SIGNALING 70 3.02e-02 1.50e-01 2.06e-01
REACTOME ORGANIC ANION TRANSPORT 5 3.04e-02 -5.59e-01 2.06e-01
REACTOME HEDGEHOG OFF STATE 111 3.05e-02 1.19e-01 2.06e-01
REACTOME INTERLEUKIN 1 SIGNALING 110 3.06e-02 1.19e-01 2.06e-01
REACTOME INTERLEUKIN 18 SIGNALING 8 3.09e-02 -4.41e-01 2.08e-01
REACTOME NEUROTOXICITY OF CLOSTRIDIUM TOXINS 10 3.15e-02 3.93e-01 2.11e-01
REACTOME NUCLEOTIDE EXCISION REPAIR 107 3.20e-02 1.20e-01 2.14e-01
REACTOME PERK REGULATES GENE EXPRESSION 31 3.21e-02 2.22e-01 2.14e-01
REACTOME RELAXIN RECEPTORS 8 3.31e-02 4.35e-01 2.19e-01
REACTOME VXPX CARGO TARGETING TO CILIUM 20 3.35e-02 -2.75e-01 2.21e-01
REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT 99 3.39e-02 1.23e-01 2.23e-01
REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR 79 3.40e-02 1.38e-01 2.23e-01
REACTOME THE PHOTOTRANSDUCTION CASCADE 32 3.49e-02 -2.15e-01 2.26e-01
REACTOME SIGNALING BY RETINOIC ACID 41 3.49e-02 1.90e-01 2.26e-01
REACTOME RIPK1 MEDIATED REGULATED NECROSIS 30 3.51e-02 2.22e-01 2.27e-01
REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS 12 3.52e-02 -3.51e-01 2.27e-01
REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA 28 3.61e-02 2.29e-01 2.31e-01
REACTOME TOXICITY OF BOTULINUM TOXIN TYPE D BOTD 5 3.65e-02 5.40e-01 2.33e-01
REACTOME ACYL CHAIN REMODELING OF DAG AND TAG 5 3.73e-02 -5.38e-01 2.38e-01
REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES 80 3.76e-02 1.34e-01 2.38e-01
REACTOME SARS COV 1 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS 16 3.77e-02 3.00e-01 2.38e-01
REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION 74 3.81e-02 -1.39e-01 2.40e-01
REACTOME INTERLEUKIN RECEPTOR SHC SIGNALING 24 3.83e-02 -2.44e-01 2.40e-01
REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION 9 3.84e-02 3.99e-01 2.40e-01
REACTOME STIMULI SENSING CHANNELS 100 3.89e-02 -1.19e-01 2.42e-01
REACTOME ACTIVATION OF MATRIX METALLOPROTEINASES 30 3.93e-02 -2.17e-01 2.44e-01
REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS 11 3.95e-02 3.59e-01 2.44e-01
REACTOME ION HOMEOSTASIS 52 3.98e-02 -1.65e-01 2.44e-01
REACTOME LYSOSPHINGOLIPID AND LPA RECEPTORS 14 3.98e-02 3.17e-01 2.44e-01
REACTOME PHASE 4 RESTING MEMBRANE POTENTIAL 19 4.06e-02 -2.71e-01 2.48e-01
REACTOME ANTIGEN PROCESSING CROSS PRESENTATION 98 4.08e-02 1.20e-01 2.48e-01
REACTOME MET INTERACTS WITH TNS PROTEINS 5 4.13e-02 -5.27e-01 2.50e-01
REACTOME FORMATION OF AXIAL MESODERM 14 4.28e-02 3.13e-01 2.58e-01
REACTOME DNA DOUBLE STRAND BREAK RESPONSE 74 4.29e-02 1.36e-01 2.58e-01
REACTOME PYRIMIDINE SALVAGE 10 4.31e-02 -3.69e-01 2.58e-01
REACTOME COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING 32 4.39e-02 2.06e-01 2.61e-01
REACTOME STAT3 NUCLEAR EVENTS DOWNSTREAM OF ALK SIGNALING 9 4.40e-02 3.88e-01 2.61e-01
REACTOME RNA POLYMERASE II TRANSCRIBES SNRNA GENES 77 4.40e-02 1.33e-01 2.61e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR4 14 4.43e-02 3.11e-01 2.61e-01
REACTOME FATTY ACIDS 15 4.45e-02 3.00e-01 2.62e-01
REACTOME HOMOLOGY DIRECTED REPAIR 132 4.51e-02 1.01e-01 2.64e-01
REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS 37 4.67e-02 1.89e-01 2.73e-01
REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES 14 4.78e-02 -3.05e-01 2.77e-01
REACTOME SYNTHESIS OF KETONE BODIES 8 4.84e-02 -4.03e-01 2.77e-01
REACTOME KETONE BODY METABOLISM 9 4.84e-02 -3.80e-01 2.77e-01
REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS 18 4.85e-02 -2.69e-01 2.77e-01
REACTOME INTERLEUKIN 2 FAMILY SIGNALING 40 4.87e-02 -1.80e-01 2.77e-01
REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT 15 4.88e-02 -2.94e-01 2.77e-01
REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER 81 4.88e-02 1.27e-01 2.77e-01
REACTOME UPTAKE AND FUNCTION OF ANTHRAX TOXINS 11 4.88e-02 -3.43e-01 2.77e-01
REACTOME FLT3 SIGNALING BY CBL MUTANTS 7 4.90e-02 4.30e-01 2.77e-01
REACTOME DEFECTIVE CHST6 CAUSES MCDC1 8 4.91e-02 -4.02e-01 2.77e-01
REACTOME SIGNALING BY FGFR2 72 4.92e-02 1.34e-01 2.77e-01
REACTOME VISUAL PHOTOTRANSDUCTION 93 4.94e-02 -1.18e-01 2.77e-01
REACTOME DEGRADATION OF AXIN 54 4.99e-02 1.54e-01 2.78e-01
REACTOME NS1 MEDIATED EFFECTS ON HOST PATHWAYS 41 5.04e-02 1.77e-01 2.80e-01
REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS 39 5.16e-02 -1.80e-01 2.86e-01
REACTOME SIGNALING BY MST1 5 5.18e-02 -5.02e-01 2.86e-01
REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A 26 5.31e-02 2.19e-01 2.92e-01
REACTOME HEDGEHOG ON STATE 85 5.34e-02 1.21e-01 2.92e-01
REACTOME PREVENTION OF PHAGOSOMAL LYSOSOMAL FUSION 9 5.36e-02 3.72e-01 2.92e-01
REACTOME BIOLOGICAL OXIDATIONS 210 5.36e-02 7.73e-02 2.92e-01
REACTOME GABA RECEPTOR ACTIVATION 57 5.40e-02 -1.48e-01 2.94e-01
REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS 63 5.50e-02 -1.40e-01 2.98e-01
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES 255 5.55e-02 -6.96e-02 3.00e-01
REACTOME INTERFERON GAMMA SIGNALING 88 5.56e-02 1.18e-01 3.00e-01
REACTOME GLYCOSAMINOGLYCAN METABOLISM 118 5.59e-02 -1.02e-01 3.00e-01
REACTOME THE NLRP3 INFLAMMASOME 16 5.61e-02 2.76e-01 3.00e-01
REACTOME COLLAGEN FORMATION 88 5.63e-02 -1.18e-01 3.00e-01
REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION 32 5.69e-02 1.94e-01 3.03e-01
REACTOME COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES 65 5.78e-02 -1.36e-01 3.06e-01
REACTOME FGFR2 LIGAND BINDING AND ACTIVATION 19 5.83e-02 2.51e-01 3.06e-01
REACTOME HYDROLYSIS OF LPC 9 5.83e-02 -3.64e-01 3.06e-01
REACTOME PROCESSING OF DNA DOUBLE STRAND BREAK ENDS 93 5.84e-02 1.14e-01 3.06e-01
REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES 39 5.84e-02 1.75e-01 3.06e-01
REACTOME FGFR2 ALTERNATIVE SPLICING 27 5.87e-02 2.10e-01 3.06e-01
REACTOME REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE 81 5.94e-02 1.21e-01 3.08e-01
REACTOME DEX H BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION 7 5.98e-02 4.11e-01 3.10e-01
REACTOME CROSSLINKING OF COLLAGEN FIBRILS 16 6.02e-02 -2.71e-01 3.11e-01
REACTOME INACTIVATION OF CDC42 AND RAC1 8 6.05e-02 -3.83e-01 3.11e-01
REACTOME SIGNALING BY WNT 318 6.12e-02 6.11e-02 3.14e-01
REACTOME NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY 6 6.14e-02 -4.41e-01 3.14e-01
REACTOME DEGRADATION OF DVL 56 6.17e-02 1.44e-01 3.15e-01
REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE 93 6.23e-02 1.12e-01 3.17e-01
REACTOME CATION COUPLED CHLORIDE COTRANSPORTERS 7 6.28e-02 -4.06e-01 3.18e-01
REACTOME COMPLEX I BIOGENESIS 49 6.30e-02 1.54e-01 3.18e-01
REACTOME RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA 7 6.35e-02 4.05e-01 3.19e-01
REACTOME RAC1 GTPASE CYCLE 172 6.36e-02 -8.20e-02 3.19e-01
REACTOME DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS 25 6.42e-02 2.14e-01 3.20e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES 49 6.42e-02 1.53e-01 3.20e-01
REACTOME FLT3 SIGNALING THROUGH SRC FAMILY KINASES 6 6.43e-02 4.36e-01 3.20e-01
REACTOME DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A 5 6.50e-02 -4.76e-01 3.22e-01
REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES 46 6.51e-02 1.57e-01 3.22e-01
REACTOME STRIATED MUSCLE CONTRACTION 35 6.59e-02 -1.80e-01 3.25e-01
REACTOME NICOTINAMIDE SALVAGING 19 6.77e-02 -2.42e-01 3.33e-01
REACTOME LAMININ INTERACTIONS 28 6.87e-02 -1.99e-01 3.36e-01
REACTOME METABOLISM OF LIPIDS 709 6.88e-02 -4.01e-02 3.36e-01
REACTOME CHAPERONE MEDIATED AUTOPHAGY 20 6.96e-02 2.34e-01 3.39e-01
REACTOME NUCLEAR EVENTS MEDIATED BY NFE2L2 77 6.97e-02 1.20e-01 3.39e-01
REACTOME FOXO MEDIATED TRANSCRIPTION 65 7.05e-02 1.30e-01 3.42e-01
REACTOME RHOBTB GTPASE CYCLE 34 7.10e-02 1.79e-01 3.42e-01
REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS 188 7.11e-02 7.63e-02 3.42e-01
REACTOME MET PROMOTES CELL MOTILITY 41 7.16e-02 -1.63e-01 3.44e-01
REACTOME LGI ADAM INTERACTIONS 14 7.25e-02 2.77e-01 3.47e-01
REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING 16 7.26e-02 2.59e-01 3.47e-01
REACTOME ACETYLCHOLINE REGULATES INSULIN SECRETION 10 7.35e-02 -3.27e-01 3.50e-01
REACTOME DISEASES OF MITOTIC CELL CYCLE 37 7.40e-02 1.70e-01 3.51e-01
REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS 63 7.48e-02 1.30e-01 3.54e-01
REACTOME SIGNALING BY THE B CELL RECEPTOR BCR 106 7.52e-02 1.00e-01 3.55e-01
REACTOME BICARBONATE TRANSPORTERS 10 7.54e-02 -3.25e-01 3.55e-01
REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES 101 7.63e-02 -1.02e-01 3.58e-01
REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION 6 7.68e-02 4.17e-01 3.58e-01
REACTOME DAP12 INTERACTIONS 37 7.70e-02 1.68e-01 3.58e-01
REACTOME INFLAMMASOMES 21 7.71e-02 2.23e-01 3.58e-01
REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM 23 7.72e-02 2.13e-01 3.58e-01
REACTOME VLDL ASSEMBLY 5 7.79e-02 4.55e-01 3.61e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES 11 7.85e-02 3.06e-01 3.61e-01
REACTOME HIV LIFE CYCLE 145 7.87e-02 8.46e-02 3.61e-01
REACTOME REDUCTION OF CYTOSOLIC CA LEVELS 11 7.87e-02 -3.06e-01 3.61e-01
REACTOME RHOJ GTPASE CYCLE 51 7.90e-02 -1.42e-01 3.61e-01
REACTOME BH3 ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI APOPTOTIC BCL 2 MEMBERS 9 7.91e-02 3.38e-01 3.61e-01
REACTOME ABC TRANSPORTER DISORDERS 76 7.99e-02 1.16e-01 3.62e-01
REACTOME UNFOLDED PROTEIN RESPONSE UPR 88 8.02e-02 1.08e-01 3.62e-01
REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS 16 8.02e-02 -2.53e-01 3.62e-01
REACTOME SIGNALING BY ALK IN CANCER 53 8.02e-02 1.39e-01 3.62e-01
REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL 58 8.05e-02 1.33e-01 3.62e-01
REACTOME HDR THROUGH SINGLE STRAND ANNEALING SSA 37 8.23e-02 1.65e-01 3.69e-01
REACTOME 2 LTR CIRCLE FORMATION 7 8.31e-02 3.78e-01 3.72e-01
REACTOME TOLL LIKE RECEPTOR CASCADES 158 8.36e-02 7.98e-02 3.73e-01
REACTOME INTEGRATION OF PROVIRUS 9 8.41e-02 3.32e-01 3.74e-01
REACTOME ACYL CHAIN REMODELLING OF PE 29 8.57e-02 -1.84e-01 3.80e-01
REACTOME ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS 24 8.67e-02 -2.02e-01 3.84e-01
REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES 91 8.85e-02 1.03e-01 3.90e-01
REACTOME FGFR1C LIGAND BINDING AND ACTIVATION 11 8.97e-02 2.96e-01 3.95e-01
REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION 15 8.99e-02 2.53e-01 3.95e-01
REACTOME CDC42 GTPASE CYCLE 144 9.08e-02 -8.16e-02 3.98e-01
REACTOME PLATELET HOMEOSTASIS 85 9.12e-02 -1.06e-01 3.98e-01
REACTOME DNA DAMAGE BYPASS 47 9.21e-02 1.42e-01 4.01e-01
REACTOME SELECTIVE AUTOPHAGY 79 9.23e-02 1.10e-01 4.01e-01
REACTOME FGFR2C LIGAND BINDING AND ACTIVATION 12 9.26e-02 2.80e-01 4.01e-01
REACTOME MET ACTIVATES RAS SIGNALING 11 9.29e-02 -2.93e-01 4.02e-01
REACTOME INTEGRATION OF ENERGY METABOLISM 105 9.44e-02 -9.45e-02 4.07e-01
REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B 24 9.50e-02 1.97e-01 4.07e-01
REACTOME LTC4 CYSLTR MEDIATED IL4 PRODUCTION 6 9.50e-02 -3.94e-01 4.07e-01
REACTOME PASSIVE TRANSPORT BY AQUAPORINS 13 9.57e-02 -2.67e-01 4.08e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS 7 9.58e-02 3.63e-01 4.08e-01
REACTOME NERVOUS SYSTEM DEVELOPMENT 552 9.59e-02 4.14e-02 4.08e-01
REACTOME PHASE II CONJUGATION OF COMPOUNDS 102 9.70e-02 9.51e-02 4.12e-01
REACTOME CIPROFLOXACIN ADME 5 9.74e-02 -4.28e-01 4.12e-01
REACTOME VIRAL MESSENGER RNA SYNTHESIS 44 9.76e-02 1.44e-01 4.12e-01
REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES 34 9.83e-02 1.64e-01 4.14e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES 61 9.89e-02 1.22e-01 4.14e-01
REACTOME DNA STRAND ELONGATION 31 9.89e-02 1.71e-01 4.14e-01
REACTOME TNF SIGNALING 54 9.96e-02 1.30e-01 4.16e-01
REACTOME RHOG GTPASE CYCLE 71 1.01e-01 -1.13e-01 4.20e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING 11 1.02e-01 2.85e-01 4.22e-01
REACTOME TOLL LIKE RECEPTOR 9 TLR9 CASCADE 100 1.02e-01 9.47e-02 4.22e-01
REACTOME ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES 59 1.02e-01 -1.23e-01 4.24e-01
REACTOME RUNX3 REGULATES YAP1 MEDIATED TRANSCRIPTION 8 1.03e-01 3.33e-01 4.24e-01
REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES 22 1.03e-01 2.01e-01 4.25e-01
REACTOME PHOSPHOLIPID METABOLISM 201 1.04e-01 -6.66e-02 4.25e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES 10 1.04e-01 2.97e-01 4.27e-01
REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS 21 1.05e-01 -2.04e-01 4.29e-01
REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS 20 1.05e-01 2.09e-01 4.29e-01
REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC 28 1.06e-01 1.76e-01 4.32e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES 29 1.07e-01 1.73e-01 4.33e-01
REACTOME POTASSIUM CHANNELS 102 1.07e-01 -9.23e-02 4.33e-01
REACTOME SIGNALING BY ACTIVIN 15 1.07e-01 2.40e-01 4.34e-01
REACTOME MUSCARINIC ACETYLCHOLINE RECEPTORS 5 1.08e-01 -4.15e-01 4.35e-01
REACTOME FCERI MEDIATED NF KB ACTIVATION 78 1.09e-01 1.05e-01 4.36e-01
REACTOME DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS 14 1.09e-01 -2.47e-01 4.36e-01
REACTOME INTRINSIC PATHWAY FOR APOPTOSIS 54 1.10e-01 1.26e-01 4.36e-01
REACTOME HS GAG BIOSYNTHESIS 28 1.10e-01 -1.75e-01 4.36e-01
REACTOME INTERLEUKIN 12 FAMILY SIGNALING 53 1.10e-01 1.27e-01 4.36e-01
REACTOME SIGNALING BY HEDGEHOG 148 1.12e-01 7.57e-02 4.43e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING 25 1.13e-01 -1.83e-01 4.43e-01
REACTOME REGULATION OF GENE EXPRESSION IN ENDOCRINE COMMITTED NEUROG3 PROGENITOR CELLS 5 1.13e-01 4.10e-01 4.43e-01
REACTOME TRYPTOPHAN CATABOLISM 14 1.13e-01 -2.45e-01 4.43e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION TERMINATION 30 1.14e-01 1.67e-01 4.49e-01
REACTOME PCP CE PATHWAY 91 1.15e-01 9.56e-02 4.50e-01
REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION 20 1.15e-01 2.03e-01 4.50e-01
REACTOME OTHER SEMAPHORIN INTERACTIONS 18 1.16e-01 -2.14e-01 4.53e-01
REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS 21 1.17e-01 1.98e-01 4.54e-01
REACTOME SIGNALLING TO ERKS 34 1.18e-01 -1.55e-01 4.56e-01
REACTOME RHOU GTPASE CYCLE 37 1.18e-01 -1.48e-01 4.57e-01
REACTOME CA DEPENDENT EVENTS 36 1.19e-01 -1.50e-01 4.57e-01
REACTOME RSK ACTIVATION 5 1.19e-01 -4.03e-01 4.57e-01
REACTOME VITAMIN C ASCORBATE METABOLISM 8 1.19e-01 3.18e-01 4.57e-01
REACTOME CELLULAR RESPONSE TO HEAT STRESS 99 1.20e-01 9.05e-02 4.59e-01
REACTOME HDR THROUGH HOMOLOGOUS RECOMBINATION HRR 66 1.20e-01 1.11e-01 4.60e-01
REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS 8 1.21e-01 -3.17e-01 4.61e-01
REACTOME ACTIVATION OF NIMA KINASES NEK9 NEK6 NEK7 7 1.23e-01 3.36e-01 4.69e-01
REACTOME SYNTHESIS OF GDP MANNOSE 5 1.23e-01 -3.98e-01 4.69e-01
REACTOME ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS 27 1.24e-01 1.71e-01 4.71e-01
REACTOME SIGNALING BY NTRKS 132 1.26e-01 7.72e-02 4.76e-01
REACTOME PROCESSING AND ACTIVATION OF SUMO 10 1.27e-01 2.79e-01 4.79e-01
REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS 33 1.27e-01 1.53e-01 4.79e-01
REACTOME COLLAGEN CHAIN TRIMERIZATION 42 1.28e-01 -1.36e-01 4.79e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2 17 1.28e-01 2.13e-01 4.79e-01
REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS 16 1.29e-01 -2.19e-01 4.82e-01
REACTOME ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS 17 1.29e-01 2.12e-01 4.83e-01
REACTOME DISEASES ASSOCIATED WITH SURFACTANT METABOLISM 9 1.31e-01 -2.91e-01 4.86e-01
REACTOME FGFR3 LIGAND BINDING AND ACTIVATION 12 1.31e-01 2.52e-01 4.86e-01
REACTOME PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING 5 1.31e-01 3.90e-01 4.86e-01
REACTOME PROTON COUPLED MONOCARBOXYLATE TRANSPORT 6 1.32e-01 -3.55e-01 4.87e-01
REACTOME DAG AND IP3 SIGNALING 40 1.32e-01 -1.38e-01 4.87e-01
REACTOME METALLOTHIONEINS BIND METALS 11 1.32e-01 2.62e-01 4.87e-01
REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC 26 1.33e-01 1.70e-01 4.90e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX 19 1.34e-01 1.99e-01 4.91e-01
REACTOME INTEGRIN CELL SURFACE INTERACTIONS 83 1.34e-01 -9.50e-02 4.92e-01
REACTOME PINK1 PRKN MEDIATED MITOPHAGY 22 1.36e-01 1.84e-01 4.94e-01
REACTOME SLC TRANSPORTER DISORDERS 94 1.36e-01 -8.90e-02 4.94e-01
REACTOME RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX 29 1.36e-01 1.60e-01 4.94e-01
REACTOME SIGNALING BY ALK 26 1.37e-01 1.69e-01 4.94e-01
REACTOME METABOLISM OF CARBOHYDRATES 279 1.37e-01 -5.17e-02 4.94e-01
REACTOME FGFR1 LIGAND BINDING AND ACTIVATION 15 1.37e-01 2.22e-01 4.94e-01
REACTOME PHOSPHORYLATION OF THE APC C 20 1.38e-01 1.92e-01 4.97e-01
REACTOME REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO 10 1.41e-01 -2.69e-01 5.07e-01
REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS 418 1.41e-01 4.19e-02 5.07e-01
REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK 28 1.42e-01 -1.60e-01 5.07e-01
REACTOME NUCLEAR IMPORT OF REV PROTEIN 34 1.42e-01 1.46e-01 5.07e-01
REACTOME THYROXINE BIOSYNTHESIS 10 1.43e-01 -2.68e-01 5.08e-01
REACTOME FIBRONECTIN MATRIX FORMATION 6 1.43e-01 -3.45e-01 5.08e-01
REACTOME BETA OXIDATION OF BUTANOYL COA TO ACETYL COA 5 1.43e-01 -3.78e-01 5.08e-01
REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX 31 1.45e-01 1.51e-01 5.10e-01
REACTOME TRP CHANNELS 27 1.46e-01 -1.62e-01 5.10e-01
REACTOME SUMO IS PROTEOLYTICALLY PROCESSED 6 1.46e-01 3.43e-01 5.10e-01
REACTOME PI METABOLISM 79 1.46e-01 -9.46e-02 5.10e-01
REACTOME RET SIGNALING 40 1.46e-01 -1.33e-01 5.10e-01
REACTOME NADE MODULATES DEATH SIGNALLING 5 1.47e-01 -3.75e-01 5.10e-01
REACTOME PTK6 REGULATES CELL CYCLE 6 1.47e-01 3.42e-01 5.10e-01
REACTOME DISEASES OF GLYCOSYLATION 137 1.47e-01 -7.18e-02 5.10e-01
REACTOME SUPPRESSION OF PHAGOSOMAL MATURATION 13 1.47e-01 2.32e-01 5.10e-01
REACTOME REGULATION OF RAS BY GAPS 66 1.47e-01 1.03e-01 5.10e-01
REACTOME ONCOGENIC MAPK SIGNALING 79 1.47e-01 -9.43e-02 5.10e-01
REACTOME NUCLEAR PORE COMPLEX NPC DISASSEMBLY 36 1.48e-01 1.39e-01 5.10e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS 7 1.48e-01 -3.16e-01 5.11e-01
REACTOME SIGNALING BY FGFR 85 1.49e-01 9.05e-02 5.12e-01
REACTOME TELOMERE C STRAND SYNTHESIS INITIATION 12 1.49e-01 2.40e-01 5.12e-01
REACTOME UBIQUINOL BIOSYNTHESIS 8 1.50e-01 2.94e-01 5.12e-01
REACTOME DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15 8 1.50e-01 -2.94e-01 5.12e-01
REACTOME CREATINE METABOLISM 9 1.50e-01 2.77e-01 5.12e-01
REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY 5 1.51e-01 -3.71e-01 5.12e-01
REACTOME DISEASES OF METABOLISM 237 1.51e-01 -5.42e-02 5.12e-01
REACTOME ACTIVATION OF C3 AND C5 6 1.51e-01 -3.39e-01 5.12e-01
REACTOME SHC1 EVENTS IN EGFR SIGNALING 14 1.51e-01 -2.22e-01 5.12e-01
REACTOME TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA 36 1.52e-01 1.38e-01 5.14e-01
REACTOME POLB DEPENDENT LONG PATCH BASE EXCISION REPAIR 8 1.53e-01 2.92e-01 5.15e-01
REACTOME HIV TRANSCRIPTION INITIATION 43 1.53e-01 1.26e-01 5.15e-01
REACTOME STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES 16 1.54e-01 -2.06e-01 5.16e-01
REACTOME LDL REMODELING 6 1.54e-01 3.36e-01 5.16e-01
REACTOME RHOC GTPASE CYCLE 71 1.54e-01 -9.77e-02 5.16e-01
REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION 13 1.55e-01 2.28e-01 5.18e-01
REACTOME MET ACTIVATES PTK2 SIGNALING 30 1.56e-01 -1.50e-01 5.19e-01
REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK 17 1.56e-01 -1.99e-01 5.20e-01
REACTOME SENSING OF DNA DOUBLE STRAND BREAKS 6 1.58e-01 3.33e-01 5.24e-01
REACTOME INSULIN PROCESSING 24 1.59e-01 1.66e-01 5.24e-01
REACTOME FCGR3A MEDIATED IL10 SYNTHESIS 36 1.60e-01 -1.35e-01 5.24e-01
REACTOME EICOSANOIDS 12 1.60e-01 2.34e-01 5.24e-01
REACTOME FORMATION OF TC NER PRE INCISION COMPLEX 51 1.60e-01 1.14e-01 5.24e-01
REACTOME SIGNALLING TO RAS 20 1.60e-01 -1.81e-01 5.24e-01
REACTOME PI3K AKT ACTIVATION 9 1.60e-01 -2.70e-01 5.24e-01
REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS 27 1.60e-01 1.56e-01 5.24e-01
REACTOME KERATAN SULFATE DEGRADATION 13 1.61e-01 -2.25e-01 5.24e-01
REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES 27 1.61e-01 1.56e-01 5.24e-01
REACTOME UNWINDING OF DNA 12 1.61e-01 2.34e-01 5.24e-01
REACTOME GLUCURONIDATION 23 1.64e-01 1.68e-01 5.30e-01
REACTOME DIGESTION AND ABSORPTION 22 1.64e-01 -1.71e-01 5.30e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS 9 1.65e-01 -2.67e-01 5.33e-01
REACTOME INOSITOL PHOSPHATE METABOLISM 45 1.66e-01 -1.19e-01 5.34e-01
REACTOME MYD88 INDEPENDENT TLR4 CASCADE 103 1.66e-01 7.90e-02 5.34e-01
REACTOME G PROTEIN BETA GAMMA SIGNALLING 30 1.67e-01 -1.46e-01 5.36e-01
REACTOME PHASE 2 PLATEAU PHASE 14 1.68e-01 -2.13e-01 5.36e-01
REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE 22 1.68e-01 -1.70e-01 5.36e-01
REACTOME HDR THROUGH MMEJ ALT NHEJ 12 1.68e-01 2.30e-01 5.36e-01
REACTOME MRNA EDITING C TO U CONVERSION 8 1.68e-01 2.81e-01 5.36e-01
REACTOME INSULIN RECEPTOR RECYCLING 29 1.69e-01 1.48e-01 5.36e-01
REACTOME PI 3K CASCADE FGFR3 17 1.70e-01 1.92e-01 5.40e-01
REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE 277 1.70e-01 4.79e-02 5.40e-01
REACTOME G1 S SPECIFIC TRANSCRIPTION 28 1.72e-01 1.49e-01 5.41e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE GIP 12 1.72e-01 2.28e-01 5.41e-01
REACTOME SUMOYLATION OF DNA METHYLATION PROTEINS 16 1.73e-01 -1.97e-01 5.41e-01
REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS 5 1.73e-01 -3.52e-01 5.41e-01
REACTOME TELOMERE C STRAND LAGGING STRAND SYNTHESIS 33 1.73e-01 1.37e-01 5.41e-01
REACTOME DISEASES OF MISMATCH REPAIR MMR 5 1.73e-01 -3.52e-01 5.41e-01
REACTOME EARLY PHASE OF HIV LIFE CYCLE 14 1.74e-01 2.10e-01 5.41e-01
REACTOME HEME SIGNALING 47 1.74e-01 -1.15e-01 5.41e-01
REACTOME ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION 28 1.74e-01 -1.49e-01 5.41e-01
REACTOME MUCOPOLYSACCHARIDOSES 10 1.75e-01 -2.48e-01 5.43e-01
REACTOME TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7 12 1.75e-01 2.26e-01 5.43e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN 21 1.75e-01 1.71e-01 5.43e-01
REACTOME ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA 5 1.76e-01 3.49e-01 5.45e-01
REACTOME COPII MEDIATED VESICLE TRANSPORT 66 1.77e-01 -9.61e-02 5.46e-01
REACTOME RA BIOSYNTHESIS PATHWAY 22 1.78e-01 1.66e-01 5.47e-01
REACTOME PI 3K CASCADE FGFR4 19 1.78e-01 1.78e-01 5.48e-01
REACTOME GPCR LIGAND BINDING 444 1.79e-01 -3.72e-02 5.49e-01
REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS 6 1.79e-01 3.17e-01 5.49e-01
REACTOME TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER 76 1.80e-01 8.90e-02 5.49e-01
REACTOME MIRO GTPASE CYCLE 8 1.80e-01 -2.74e-01 5.49e-01
REACTOME TNFR1 INDUCED PROAPOPTOTIC SIGNALING 23 1.81e-01 1.61e-01 5.50e-01
REACTOME NFE2L2 REGULATING ANTI OXIDANT DETOXIFICATION ENZYMES 17 1.81e-01 -1.87e-01 5.50e-01
REACTOME CITRIC ACID CYCLE TCA CYCLE 21 1.81e-01 1.68e-01 5.50e-01
REACTOME RHO GTPASES ACTIVATE WASPS AND WAVES 34 1.82e-01 1.32e-01 5.51e-01
REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND 14 1.83e-01 2.06e-01 5.53e-01
REACTOME CLEC7A DECTIN 1 SIGNALING 97 1.84e-01 7.81e-02 5.54e-01
REACTOME DUAL INCISION IN GG NER 39 1.84e-01 1.23e-01 5.54e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES 12 1.85e-01 -2.21e-01 5.56e-01
REACTOME RNA POLYMERASE II PRE TRANSCRIPTION EVENTS 77 1.85e-01 8.73e-02 5.56e-01
REACTOME DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS 19 1.87e-01 1.75e-01 5.59e-01
REACTOME MINERALOCORTICOID BIOSYNTHESIS 6 1.87e-01 -3.11e-01 5.59e-01
REACTOME SIGNALING BY MET 78 1.87e-01 -8.63e-02 5.59e-01
REACTOME IRON UPTAKE AND TRANSPORT 56 1.88e-01 1.02e-01 5.60e-01
REACTOME SIGNALING BY PDGF 57 1.88e-01 -1.01e-01 5.60e-01
REACTOME BIOTIN TRANSPORT AND METABOLISM 10 1.88e-01 -2.40e-01 5.60e-01
REACTOME DEFECTIVE CHST14 CAUSES EDS MUSCULOCONTRACTURAL TYPE 7 1.90e-01 2.86e-01 5.62e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS 14 1.91e-01 -2.02e-01 5.63e-01
REACTOME SODIUM CALCIUM EXCHANGERS 11 1.91e-01 -2.28e-01 5.63e-01
REACTOME PYROPTOSIS 27 1.91e-01 1.45e-01 5.63e-01
REACTOME RAF ACTIVATION 33 1.92e-01 -1.31e-01 5.64e-01
REACTOME SIGNALING BY FGFR2 IN DISEASE 42 1.92e-01 1.16e-01 5.64e-01
REACTOME PKMTS METHYLATE HISTONE LYSINES 64 1.94e-01 9.39e-02 5.68e-01
REACTOME SIGNALING BY VEGF 102 1.94e-01 -7.44e-02 5.68e-01
REACTOME VEGFR2 MEDIATED CELL PROLIFERATION 19 1.97e-01 -1.71e-01 5.75e-01
REACTOME FREE FATTY ACIDS REGULATE INSULIN SECRETION 10 1.98e-01 -2.35e-01 5.76e-01
REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS 53 1.98e-01 1.02e-01 5.78e-01
REACTOME PHYSIOLOGICAL FACTORS 14 2.00e-01 1.98e-01 5.79e-01
REACTOME HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE 43 2.00e-01 1.13e-01 5.79e-01
REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ 6 2.01e-01 -3.01e-01 5.79e-01
REACTOME TIE2 SIGNALING 18 2.01e-01 -1.74e-01 5.79e-01
REACTOME OPIOID SIGNALLING 89 2.02e-01 -7.83e-02 5.79e-01
REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY 14 2.02e-01 -1.97e-01 5.79e-01
REACTOME C TYPE LECTIN RECEPTORS CLRS 136 2.02e-01 6.34e-02 5.79e-01
REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS 55 2.02e-01 -9.94e-02 5.79e-01
REACTOME DAP12 SIGNALING 27 2.03e-01 1.42e-01 5.79e-01
REACTOME MITOPHAGY 28 2.03e-01 1.39e-01 5.79e-01
REACTOME PEROXISOMAL PROTEIN IMPORT 62 2.03e-01 9.34e-02 5.79e-01
REACTOME PARACETAMOL ADME 26 2.03e-01 -1.44e-01 5.79e-01
REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY 26 2.04e-01 -1.44e-01 5.81e-01
REACTOME DRUG MEDIATED INHIBITION OF CDK4 CDK6 ACTIVITY 5 2.07e-01 3.26e-01 5.86e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1 16 2.07e-01 1.82e-01 5.86e-01
REACTOME FATTY ACIDS BOUND TO GPR40 FFAR1 REGULATE INSULIN SECRETION 8 2.07e-01 -2.58e-01 5.87e-01
REACTOME NUCLEAR ENVELOPE BREAKDOWN 52 2.08e-01 1.01e-01 5.88e-01
REACTOME SIGNALLING TO P38 VIA RIT AND RIN 5 2.09e-01 -3.24e-01 5.88e-01
REACTOME RHOV GTPASE CYCLE 36 2.09e-01 -1.21e-01 5.88e-01
REACTOME SARS COV 2 ACTIVATES MODULATES INNATE AND ADAPTIVE IMMUNE RESPONSES 118 2.09e-01 6.69e-02 5.88e-01
REACTOME MET RECEPTOR ACTIVATION 6 2.09e-01 -2.96e-01 5.88e-01
REACTOME ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS 20 2.12e-01 1.61e-01 5.94e-01
REACTOME SPERM MOTILITY AND TAXES 9 2.12e-01 2.40e-01 5.94e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE 20 2.13e-01 1.61e-01 5.94e-01
REACTOME VITAMINS 6 2.13e-01 2.94e-01 5.94e-01
REACTOME SERINE BIOSYNTHESIS 9 2.14e-01 2.39e-01 5.97e-01
REACTOME REGULATION OF LIPID METABOLISM BY PPARALPHA 115 2.16e-01 -6.68e-02 6.00e-01
REACTOME NRAGE SIGNALS DEATH THROUGH JNK 53 2.17e-01 -9.80e-02 6.01e-01
REACTOME POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE 25 2.17e-01 1.43e-01 6.01e-01
REACTOME TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY 16 2.18e-01 1.78e-01 6.01e-01
REACTOME INFECTION WITH MYCOBACTERIUM TUBERCULOSIS 25 2.18e-01 1.42e-01 6.02e-01
REACTOME CROSS PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS PHAGOSOMES 6 2.20e-01 -2.89e-01 6.03e-01
REACTOME ACTIVATION OF BH3 ONLY PROTEINS 30 2.20e-01 1.29e-01 6.03e-01
REACTOME REGULATION OF SIGNALING BY NODAL 9 2.20e-01 2.36e-01 6.03e-01
REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION 36 2.20e-01 1.18e-01 6.03e-01
REACTOME DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE 17 2.21e-01 1.72e-01 6.03e-01
REACTOME CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT 19 2.21e-01 1.62e-01 6.03e-01
REACTOME AZATHIOPRINE ADME 22 2.22e-01 -1.50e-01 6.03e-01
REACTOME G0 AND EARLY G1 27 2.22e-01 1.36e-01 6.03e-01
REACTOME CRISTAE FORMATION 27 2.23e-01 1.36e-01 6.03e-01
REACTOME OPSINS 7 2.23e-01 -2.66e-01 6.03e-01
REACTOME ATTENUATION PHASE 27 2.23e-01 1.36e-01 6.03e-01
REACTOME INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS 37 2.23e-01 1.16e-01 6.03e-01
REACTOME SIALIC ACID METABOLISM 33 2.24e-01 -1.22e-01 6.05e-01
REACTOME ALK MUTANTS BIND TKIS 12 2.25e-01 2.02e-01 6.07e-01
REACTOME GLYCOLYSIS 70 2.25e-01 8.38e-02 6.07e-01
REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS 118 2.26e-01 -6.45e-02 6.07e-01
REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS 42 2.27e-01 -1.08e-01 6.07e-01
REACTOME EPHA MEDIATED GROWTH CONE COLLAPSE 29 2.27e-01 -1.30e-01 6.07e-01
REACTOME SURFACTANT METABOLISM 28 2.28e-01 -1.32e-01 6.07e-01
REACTOME DEFECTIVE CSF2RB CAUSES SMDP5 7 2.28e-01 -2.63e-01 6.07e-01
REACTOME RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR 19 2.29e-01 -1.60e-01 6.07e-01
REACTOME REGULATION OF PTEN STABILITY AND ACTIVITY 67 2.29e-01 8.49e-02 6.07e-01
REACTOME DOPAMINE RECEPTORS 5 2.30e-01 -3.10e-01 6.07e-01
REACTOME STAT5 ACTIVATION 7 2.30e-01 2.62e-01 6.07e-01
REACTOME RAP1 SIGNALLING 16 2.30e-01 1.73e-01 6.07e-01
REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS 11 2.30e-01 -2.09e-01 6.07e-01
REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE 17 2.30e-01 -1.68e-01 6.07e-01
REACTOME GPER1 SIGNALING 45 2.31e-01 -1.03e-01 6.07e-01
REACTOME SIGNALING BY INSULIN RECEPTOR 80 2.32e-01 7.73e-02 6.07e-01
REACTOME EXTENSION OF TELOMERES 49 2.32e-01 9.87e-02 6.07e-01
REACTOME OAS ANTIVIRAL RESPONSE 8 2.32e-01 2.44e-01 6.07e-01
REACTOME SHC MEDIATED CASCADE FGFR3 17 2.33e-01 1.67e-01 6.07e-01
REACTOME TAK1 DEPENDENT IKK AND NF KAPPA B ACTIVATION 41 2.34e-01 1.07e-01 6.07e-01
REACTOME MISCELLANEOUS SUBSTRATES 12 2.34e-01 1.98e-01 6.07e-01
REACTOME RHO GTPASES ACTIVATE PAKS 19 2.35e-01 -1.58e-01 6.07e-01
REACTOME DEADENYLATION DEPENDENT MRNA DECAY 56 2.36e-01 9.16e-02 6.07e-01
REACTOME CD28 CO STIMULATION 32 2.36e-01 -1.21e-01 6.07e-01
REACTOME PHOSPHORYLATION OF EMI1 6 2.36e-01 2.79e-01 6.07e-01
REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE 69 2.37e-01 -8.24e-02 6.07e-01
REACTOME FORMATION OF INCISION COMPLEX IN GG NER 40 2.37e-01 1.08e-01 6.07e-01
REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION 35 2.37e-01 1.16e-01 6.07e-01
REACTOME RETINOID CYCLE DISEASE EVENTS 11 2.37e-01 -2.06e-01 6.07e-01
REACTOME ABACAVIR TRANSMEMBRANE TRANSPORT 5 2.37e-01 -3.05e-01 6.07e-01
REACTOME ACTIVATION OF CASPASES THROUGH APOPTOSOME MEDIATED CLEAVAGE 5 2.37e-01 3.05e-01 6.07e-01
REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION 23 2.38e-01 -1.42e-01 6.07e-01
REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING 29 2.38e-01 -1.27e-01 6.07e-01
REACTOME TRNA MODIFICATION IN THE MITOCHONDRION 8 2.39e-01 2.41e-01 6.07e-01
REACTOME SHC MEDIATED CASCADE FGFR4 19 2.39e-01 1.56e-01 6.07e-01
REACTOME MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS 7 2.39e-01 2.57e-01 6.07e-01
REACTOME CLEC7A INFLAMMASOME PATHWAY 6 2.39e-01 2.77e-01 6.07e-01
REACTOME CHYLOMICRON REMODELING 10 2.40e-01 -2.15e-01 6.07e-01
REACTOME RND1 GTPASE CYCLE 41 2.40e-01 -1.06e-01 6.07e-01
REACTOME SUMOYLATION OF UBIQUITINYLATION PROTEINS 39 2.40e-01 1.09e-01 6.07e-01
REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI 26 2.40e-01 -1.33e-01 6.07e-01
REACTOME ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE 9 2.41e-01 -2.26e-01 6.07e-01
REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM 50 2.41e-01 -9.58e-02 6.07e-01
REACTOME LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX 5 2.42e-01 -3.02e-01 6.07e-01
REACTOME FANCONI ANEMIA PATHWAY 35 2.43e-01 1.14e-01 6.07e-01
REACTOME SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS 43 2.43e-01 -1.03e-01 6.07e-01
REACTOME CILIUM ASSEMBLY 190 2.43e-01 4.91e-02 6.07e-01
REACTOME AQUAPORIN MEDIATED TRANSPORT 51 2.43e-01 -9.45e-02 6.07e-01
REACTOME NEGATIVE REGULATION OF FLT3 15 2.43e-01 1.74e-01 6.07e-01
REACTOME ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA 15 2.43e-01 1.74e-01 6.07e-01
REACTOME DEFECTIVE B4GALT1 CAUSES B4GALT1 CDG CDG 2D 8 2.44e-01 -2.38e-01 6.08e-01
REACTOME DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1 9 2.44e-01 2.24e-01 6.08e-01
REACTOME GLUCOSE METABOLISM 90 2.45e-01 7.10e-02 6.08e-01
REACTOME LIGAND RECEPTOR INTERACTIONS 8 2.46e-01 2.37e-01 6.09e-01
REACTOME ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS 11 2.46e-01 2.02e-01 6.09e-01
REACTOME LOSS OF FUNCTION OF SMAD2 3 IN CANCER 7 2.46e-01 2.53e-01 6.09e-01
REACTOME FGFRL1 MODULATION OF FGFR1 SIGNALING 13 2.47e-01 1.85e-01 6.11e-01
REACTOME SYNTHESIS OF PA 38 2.48e-01 -1.08e-01 6.13e-01
REACTOME NUCLEOTIDE SALVAGE 21 2.49e-01 -1.45e-01 6.13e-01
REACTOME NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 25 2.49e-01 1.33e-01 6.13e-01
REACTOME TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS 43 2.52e-01 1.01e-01 6.19e-01
REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION 160 2.53e-01 5.24e-02 6.19e-01
REACTOME RUNX2 REGULATES CHONDROCYTE MATURATION 5 2.53e-01 -2.95e-01 6.19e-01
REACTOME INTESTINAL ABSORPTION 5 2.54e-01 -2.94e-01 6.21e-01
REACTOME EGFR TRANSACTIVATION BY GASTRIN 9 2.55e-01 -2.19e-01 6.21e-01
REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS 62 2.55e-01 -8.36e-02 6.21e-01
REACTOME TRANSCRIPTION OF THE HIV GENOME 66 2.56e-01 8.09e-02 6.21e-01
REACTOME SEMAPHORIN INTERACTIONS 61 2.56e-01 -8.41e-02 6.21e-01
REACTOME MODULATION BY MTB OF HOST IMMUNE SYSTEM 6 2.57e-01 2.67e-01 6.21e-01
REACTOME DUAL INCISION IN TC NER 63 2.57e-01 8.26e-02 6.21e-01
REACTOME CA2 PATHWAY 62 2.57e-01 -8.32e-02 6.21e-01
REACTOME REGULATION OF KIT SIGNALING 16 2.58e-01 1.63e-01 6.21e-01
REACTOME CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY 12 2.58e-01 1.89e-01 6.21e-01
REACTOME VITAMIN B2 RIBOFLAVIN METABOLISM 7 2.59e-01 2.47e-01 6.21e-01
REACTOME MTOR SIGNALLING 40 2.59e-01 -1.03e-01 6.21e-01
REACTOME APOPTOTIC FACTOR MEDIATED RESPONSE 19 2.59e-01 1.49e-01 6.21e-01
REACTOME THE ACTIVATION OF ARYLSULFATASES 8 2.59e-01 -2.30e-01 6.21e-01
REACTOME TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY 30 2.60e-01 1.19e-01 6.21e-01
REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING 30 2.60e-01 1.19e-01 6.21e-01
REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING 28 2.60e-01 1.23e-01 6.21e-01
REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 11 2.61e-01 1.96e-01 6.23e-01
REACTOME SIGNALING BY NOTCH2 32 2.62e-01 1.15e-01 6.23e-01
REACTOME GAB1 SIGNALOSOME 17 2.62e-01 -1.57e-01 6.23e-01
REACTOME HS GAG DEGRADATION 19 2.64e-01 1.48e-01 6.26e-01
REACTOME PROLONGED ERK ACTIVATION EVENTS 14 2.65e-01 -1.72e-01 6.27e-01
REACTOME DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE 30 2.67e-01 1.17e-01 6.30e-01
REACTOME P38MAPK EVENTS 13 2.67e-01 -1.78e-01 6.30e-01
REACTOME SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION 8 2.67e-01 -2.27e-01 6.30e-01
REACTOME PI 3K CASCADE FGFR1 21 2.69e-01 1.39e-01 6.32e-01
REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION 9 2.69e-01 2.13e-01 6.32e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES 15 2.70e-01 1.64e-01 6.33e-01
REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION 32 2.70e-01 -1.13e-01 6.33e-01
REACTOME ENDOGENOUS STEROLS 26 2.70e-01 -1.25e-01 6.33e-01
REACTOME SIGNAL TRANSDUCTION BY L1 20 2.73e-01 -1.42e-01 6.39e-01
REACTOME ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION 16 2.73e-01 -1.58e-01 6.39e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION 45 2.75e-01 9.40e-02 6.42e-01
REACTOME GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION 14 2.75e-01 1.68e-01 6.42e-01
REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS 9 2.76e-01 -2.10e-01 6.42e-01
REACTOME FRUCTOSE METABOLISM 7 2.76e-01 -2.38e-01 6.42e-01
REACTOME KEAP1 NFE2L2 PATHWAY 104 2.77e-01 6.17e-02 6.42e-01
REACTOME REGULATION OF INSULIN SECRETION 77 2.77e-01 -7.16e-02 6.42e-01
REACTOME RIP MEDIATED NFKB ACTIVATION VIA ZBP1 16 2.78e-01 1.57e-01 6.43e-01
REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION 42 2.79e-01 -9.66e-02 6.43e-01
REACTOME RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION 6 2.80e-01 2.55e-01 6.45e-01
REACTOME MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS 17 2.81e-01 1.51e-01 6.45e-01
REACTOME INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE 20 2.81e-01 1.39e-01 6.45e-01
REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS 68 2.82e-01 7.55e-02 6.46e-01
REACTOME PEXOPHAGY 11 2.83e-01 1.87e-01 6.46e-01
REACTOME TRANSPORT OF RCBL WITHIN THE BODY 8 2.83e-01 2.19e-01 6.46e-01
REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS 32 2.83e-01 -1.10e-01 6.46e-01
REACTOME FERTILIZATION 26 2.83e-01 1.22e-01 6.46e-01
REACTOME AGGREPHAGY 42 2.84e-01 9.56e-02 6.46e-01
REACTOME INDUCTION OF CELL CELL FUSION 12 2.84e-01 -1.79e-01 6.46e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES 33 2.85e-01 1.08e-01 6.46e-01
REACTOME SYNTHESIS OF PC 27 2.85e-01 1.19e-01 6.46e-01
REACTOME SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS 16 2.85e-01 -1.54e-01 6.46e-01
REACTOME INTERLEUKIN 12 SIGNALING 43 2.86e-01 9.41e-02 6.46e-01
REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE 71 2.86e-01 7.33e-02 6.46e-01
REACTOME RESOLUTION OF ABASIC SITES AP SITES 38 2.88e-01 9.97e-02 6.48e-01
REACTOME LYSOSOME VESICLE BIOGENESIS 33 2.88e-01 1.07e-01 6.48e-01
REACTOME DERMATAN SULFATE BIOSYNTHESIS 10 2.88e-01 1.94e-01 6.48e-01
REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN 32 2.89e-01 1.08e-01 6.51e-01
REACTOME ADHERENS JUNCTIONS INTERACTIONS 33 2.90e-01 -1.06e-01 6.51e-01
REACTOME TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE 39 2.91e-01 9.77e-02 6.53e-01
REACTOME ACYL CHAIN REMODELLING OF PI 17 2.92e-01 -1.48e-01 6.53e-01
REACTOME DNA REPLICATION INITIATION 7 2.94e-01 2.29e-01 6.57e-01
REACTOME HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR IN THE PRESENCE OF LIGAND 55 2.94e-01 8.18e-02 6.57e-01
REACTOME GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION 34 2.95e-01 -1.04e-01 6.58e-01
REACTOME GERM LAYER FORMATION AT GASTRULATION 17 2.95e-01 1.47e-01 6.58e-01
REACTOME SIGNALING BY FGFR2 IIIA TM 19 2.96e-01 1.39e-01 6.58e-01
REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY 25 2.97e-01 1.20e-01 6.60e-01
REACTOME NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 22 2.98e-01 1.28e-01 6.60e-01
REACTOME REPRESSION OF WNT TARGET GENES 14 2.98e-01 1.61e-01 6.60e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH CDK5 6 2.98e-01 2.45e-01 6.60e-01
REACTOME PROCESSING OF INTRONLESS PRE MRNAS 19 2.99e-01 1.38e-01 6.60e-01
REACTOME MITOCHONDRIAL UNCOUPLING 5 3.00e-01 -2.68e-01 6.61e-01
REACTOME LATE ENDOSOMAL MICROAUTOPHAGY 33 3.00e-01 1.04e-01 6.61e-01
REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS 312 3.01e-01 -3.41e-02 6.61e-01
REACTOME SUMO IS CONJUGATED TO E1 UBA2 SAE1 5 3.01e-01 2.67e-01 6.61e-01
REACTOME SYNTHESIS OF PE 13 3.01e-01 1.66e-01 6.61e-01
REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION 31 3.02e-01 1.07e-01 6.61e-01
REACTOME TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS 26 3.02e-01 1.17e-01 6.61e-01
REACTOME REACTIONS SPECIFIC TO THE COMPLEX N GLYCAN SYNTHESIS PATHWAY 10 3.03e-01 -1.88e-01 6.61e-01
REACTOME SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL 8 3.03e-01 -2.10e-01 6.61e-01
REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE 20 3.03e-01 -1.33e-01 6.61e-01
REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS 15 3.04e-01 -1.53e-01 6.62e-01
REACTOME REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA 15 3.05e-01 -1.53e-01 6.62e-01
REACTOME SMAC XIAP REGULATED APOPTOTIC RESPONSE 7 3.05e-01 2.24e-01 6.62e-01
REACTOME EPITHELIAL MESENCHYMAL TRANSITION EMT DURING GASTRULATION 7 3.06e-01 2.24e-01 6.63e-01
REACTOME DISEASES OF IMMUNE SYSTEM 29 3.07e-01 1.10e-01 6.65e-01
REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN 15 3.08e-01 -1.52e-01 6.67e-01
REACTOME REGULATION OF FZD BY UBIQUITINATION 21 3.10e-01 -1.28e-01 6.67e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS 9 3.10e-01 -1.96e-01 6.67e-01
REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS 35 3.10e-01 9.92e-02 6.67e-01
REACTOME REGULATION OF NPAS4 MRNA TRANSLATION 9 3.10e-01 -1.95e-01 6.67e-01
REACTOME IRF3 MEDIATED INDUCTION OF TYPE I IFN 13 3.10e-01 -1.63e-01 6.67e-01
REACTOME SODIUM COUPLED PHOSPHATE COTRANSPORTERS 5 3.11e-01 -2.62e-01 6.67e-01
REACTOME TRNA AMINOACYLATION 40 3.12e-01 9.25e-02 6.68e-01
REACTOME JOSEPHIN DOMAIN DUBS 11 3.12e-01 1.76e-01 6.69e-01
REACTOME TACHYKININ RECEPTORS BIND TACHYKININS 5 3.13e-01 -2.61e-01 6.69e-01
REACTOME TRANSLESION SYNTHESIS BY POLK 17 3.15e-01 1.41e-01 6.72e-01
REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX 8 3.16e-01 2.05e-01 6.73e-01
REACTOME GROWTH HORMONE RECEPTOR SIGNALING 24 3.17e-01 -1.18e-01 6.73e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN 13 3.17e-01 -1.60e-01 6.73e-01
REACTOME DIGESTION OF DIETARY LIPID 7 3.17e-01 -2.18e-01 6.73e-01
REACTOME HSF1 ACTIVATION 29 3.19e-01 1.07e-01 6.77e-01
REACTOME ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS 87 3.20e-01 -6.17e-02 6.77e-01
REACTOME PTK6 EXPRESSION 5 3.20e-01 2.57e-01 6.77e-01
REACTOME LAGGING STRAND SYNTHESIS 19 3.20e-01 1.32e-01 6.77e-01
REACTOME SIGNALING BY RECEPTOR TYROSINE KINASES 507 3.21e-01 2.57e-02 6.77e-01
REACTOME EGFR INTERACTS WITH PHOSPHOLIPASE C GAMMA 9 3.21e-01 -1.91e-01 6.77e-01
REACTOME PROTEIN REPAIR 6 3.21e-01 2.34e-01 6.77e-01
REACTOME NOSTRIN MEDIATED ENOS TRAFFICKING 5 3.22e-01 2.56e-01 6.77e-01
REACTOME INTERLEUKIN 6 FAMILY SIGNALING 24 3.22e-01 1.17e-01 6.77e-01
REACTOME NONCANONICAL ACTIVATION OF NOTCH3 8 3.23e-01 2.02e-01 6.78e-01
REACTOME FORMATION OF PARAXIAL MESODERM 22 3.23e-01 -1.22e-01 6.78e-01
REACTOME PI 3K CASCADE FGFR2 22 3.25e-01 1.21e-01 6.79e-01
REACTOME FGFR3B LIGAND BINDING AND ACTIVATION 7 3.25e-01 2.15e-01 6.79e-01
REACTOME RIBAVIRIN ADME 11 3.25e-01 -1.71e-01 6.79e-01
REACTOME PHASE 0 RAPID DEPOLARISATION 31 3.27e-01 -1.02e-01 6.80e-01
REACTOME ACTIVATION OF RAC1 12 3.27e-01 -1.64e-01 6.80e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS 9 3.27e-01 -1.89e-01 6.80e-01
REACTOME RHOD GTPASE CYCLE 49 3.29e-01 -8.06e-02 6.82e-01
REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE 19 3.29e-01 1.29e-01 6.82e-01
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION 81 3.31e-01 6.25e-02 6.85e-01
REACTOME ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS 7 3.32e-01 -2.12e-01 6.85e-01
REACTOME KERATAN SULFATE BIOSYNTHESIS 28 3.32e-01 -1.06e-01 6.85e-01
REACTOME P75NTR SIGNALS VIA NF KB 15 3.32e-01 1.45e-01 6.85e-01
REACTOME CELL CELL COMMUNICATION 126 3.33e-01 -5.00e-02 6.85e-01
REACTOME GABA B RECEPTOR ACTIVATION 43 3.33e-01 -8.53e-02 6.85e-01
REACTOME HDL ASSEMBLY 8 3.34e-01 -1.97e-01 6.85e-01
REACTOME DIGESTION 17 3.34e-01 -1.35e-01 6.85e-01
REACTOME PENTOSE PHOSPHATE PATHWAY 12 3.35e-01 -1.61e-01 6.85e-01
REACTOME FC EPSILON RECEPTOR FCERI SIGNALING 127 3.35e-01 4.95e-02 6.85e-01
REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS 21 3.35e-01 1.22e-01 6.85e-01
REACTOME SIGNALING BY NOTCH1 69 3.36e-01 6.70e-02 6.86e-01
REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE 37 3.37e-01 -9.13e-02 6.87e-01
REACTOME GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION 42 3.38e-01 -8.54e-02 6.88e-01
REACTOME CD28 DEPENDENT PI3K AKT SIGNALING 22 3.39e-01 -1.18e-01 6.89e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR4 26 3.40e-01 1.08e-01 6.89e-01
REACTOME SYNTHESIS OF 15 EICOSATETRAENOIC ACID DERIVATIVES 6 3.41e-01 -2.24e-01 6.89e-01
REACTOME CD22 MEDIATED BCR REGULATION 5 3.42e-01 2.45e-01 6.89e-01
REACTOME PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS 21 3.42e-01 -1.20e-01 6.89e-01
REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE 20 3.42e-01 1.23e-01 6.89e-01
REACTOME FLT3 SIGNALING IN DISEASE 28 3.42e-01 1.04e-01 6.89e-01
REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING 32 3.42e-01 9.70e-02 6.89e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR3 24 3.42e-01 1.12e-01 6.89e-01
REACTOME HEME DEGRADATION 15 3.43e-01 -1.41e-01 6.89e-01
REACTOME PRE NOTCH PROCESSING IN GOLGI 18 3.43e-01 -1.29e-01 6.89e-01
REACTOME SHC MEDIATED CASCADE FGFR1 21 3.45e-01 1.19e-01 6.92e-01
REACTOME TLR3 MEDIATED TICAM1 DEPENDENT PROGRAMMED CELL DEATH 6 3.46e-01 2.22e-01 6.94e-01
REACTOME RND2 GTPASE CYCLE 42 3.47e-01 -8.38e-02 6.95e-01
REACTOME GLYCEROPHOSPHOLIPID CATABOLISM 7 3.48e-01 -2.05e-01 6.95e-01
REACTOME CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION 11 3.48e-01 -1.63e-01 6.95e-01
REACTOME SYNTHESIS OF 5 EICOSATETRAENOIC ACIDS 9 3.49e-01 -1.80e-01 6.96e-01
REACTOME MRNA CAPPING 28 3.50e-01 1.02e-01 6.97e-01
REACTOME PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR 21 3.51e-01 1.18e-01 6.97e-01
REACTOME KERATAN SULFATE KERATIN METABOLISM 34 3.51e-01 -9.25e-02 6.97e-01
REACTOME SUMOYLATION OF DNA REPLICATION PROTEINS 46 3.51e-01 7.95e-02 6.97e-01
REACTOME COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING 38 3.51e-01 8.74e-02 6.97e-01
REACTOME METHYLATION 14 3.52e-01 1.44e-01 6.97e-01
REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R 52 3.52e-01 7.45e-02 6.97e-01
REACTOME GASTRULATION 49 3.53e-01 7.67e-02 6.98e-01
REACTOME FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS 8 3.56e-01 -1.89e-01 7.02e-01
REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE 11 3.57e-01 1.60e-01 7.04e-01
REACTOME IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN 5 3.57e-01 -2.38e-01 7.04e-01
REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS 17 3.59e-01 1.28e-01 7.06e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH RAS 8 3.59e-01 -1.87e-01 7.06e-01
REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES 7 3.60e-01 -2.00e-01 7.06e-01
REACTOME SIGNALING BY FGFR IN DISEASE 62 3.61e-01 6.71e-02 7.07e-01
REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM 45 3.61e-01 -7.86e-02 7.07e-01
REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION 13 3.62e-01 -1.46e-01 7.07e-01
REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX 57 3.63e-01 6.97e-02 7.08e-01
REACTOME ANDROGEN BIOSYNTHESIS 11 3.63e-01 -1.58e-01 7.08e-01
REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS 123 3.66e-01 -4.72e-02 7.13e-01
REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING 34 3.66e-01 8.95e-02 7.13e-01
REACTOME SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER 54 3.67e-01 7.10e-02 7.13e-01
REACTOME RESPONSE OF MTB TO PHAGOCYTOSIS 22 3.68e-01 1.11e-01 7.14e-01
REACTOME DEFECTS IN BIOTIN BTN METABOLISM 8 3.69e-01 -1.83e-01 7.14e-01
REACTOME FRS MEDIATED FGFR4 SIGNALING 21 3.69e-01 1.13e-01 7.14e-01
REACTOME TRANSCRIPTIONAL REGULATION BY VENTX 41 3.69e-01 8.10e-02 7.14e-01
REACTOME LIPID PARTICLE ORGANIZATION 6 3.71e-01 -2.11e-01 7.14e-01
REACTOME FRS MEDIATED FGFR3 SIGNALING 19 3.71e-01 1.19e-01 7.14e-01
REACTOME N GLYCAN TRIMMING AND ELONGATION IN THE CIS GOLGI 5 3.71e-01 2.31e-01 7.14e-01
REACTOME SYNTHESIS OF UDP N ACETYL GLUCOSAMINE 7 3.71e-01 1.95e-01 7.14e-01
REACTOME BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS 10 3.72e-01 -1.63e-01 7.14e-01
REACTOME TRAFFICKING OF AMPA RECEPTORS 29 3.72e-01 -9.58e-02 7.14e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER 28 3.72e-01 9.74e-02 7.14e-01
REACTOME CONDENSATION OF PROMETAPHASE CHROMOSOMES 11 3.73e-01 1.55e-01 7.14e-01
REACTOME BETA CATENIN PHOSPHORYLATION CASCADE 16 3.73e-01 1.29e-01 7.15e-01
REACTOME NICOTINATE METABOLISM 31 3.76e-01 -9.19e-02 7.19e-01
REACTOME FORMATION OF LATERAL PLATE MESODERM 5 3.77e-01 2.28e-01 7.19e-01
REACTOME DSCAM INTERACTIONS 11 3.77e-01 -1.54e-01 7.19e-01
REACTOME ORGANIC CATION TRANSPORT 10 3.78e-01 -1.61e-01 7.19e-01
REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE 21 3.78e-01 -1.11e-01 7.19e-01
REACTOME COPI MEDIATED ANTEROGRADE TRANSPORT 101 3.78e-01 5.07e-02 7.19e-01
REACTOME BIOSYNTHESIS OF MARESINS 8 3.80e-01 1.79e-01 7.20e-01
REACTOME CHONDROITIN SULFATE BIOSYNTHESIS 18 3.81e-01 -1.19e-01 7.22e-01
REACTOME FASL CD95L SIGNALING 5 3.83e-01 2.25e-01 7.25e-01
REACTOME SOS MEDIATED SIGNALLING 7 3.84e-01 -1.90e-01 7.25e-01
REACTOME COSTIMULATION BY THE CD28 FAMILY 64 3.84e-01 6.29e-02 7.25e-01
REACTOME COHESIN LOADING ONTO CHROMATIN 8 3.85e-01 -1.78e-01 7.25e-01
REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS 12 3.85e-01 1.45e-01 7.25e-01
REACTOME ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN 13 3.86e-01 -1.39e-01 7.26e-01
REACTOME PLASMA LIPOPROTEIN CLEARANCE 37 3.87e-01 8.22e-02 7.27e-01
REACTOME G ALPHA 12 13 SIGNALLING EVENTS 74 3.87e-01 -5.81e-02 7.27e-01
REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET 8 3.88e-01 1.76e-01 7.28e-01
REACTOME HIV TRANSCRIPTION ELONGATION 42 3.89e-01 7.68e-02 7.28e-01
REACTOME NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 11 3.89e-01 1.50e-01 7.28e-01
REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION 16 3.90e-01 -1.24e-01 7.29e-01
REACTOME TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA 17 3.91e-01 1.20e-01 7.29e-01
REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE 15 3.91e-01 1.28e-01 7.29e-01
REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING 33 3.92e-01 8.62e-02 7.29e-01
REACTOME VOLTAGE GATED POTASSIUM CHANNELS 42 3.92e-01 -7.64e-02 7.29e-01
REACTOME RAC2 GTPASE CYCLE 81 3.92e-01 -5.50e-02 7.29e-01
REACTOME ACTIVATION OF SMO 18 3.93e-01 1.16e-01 7.29e-01
REACTOME TERMINATION OF TRANSLESION DNA SYNTHESIS 32 3.93e-01 8.73e-02 7.29e-01
REACTOME SEMA4D IN SEMAPHORIN SIGNALING 24 3.94e-01 -1.01e-01 7.29e-01
REACTOME FREE FATTY ACID RECEPTORS 5 3.94e-01 2.20e-01 7.29e-01
REACTOME MET ACTIVATES PI3K AKT SIGNALING 6 3.96e-01 -2.00e-01 7.33e-01
REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL 13 3.98e-01 -1.36e-01 7.34e-01
REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB 19 3.99e-01 -1.12e-01 7.35e-01
REACTOME RHO GTPASE CYCLE 423 3.99e-01 -2.39e-02 7.35e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX IN CANCER 8 4.00e-01 1.72e-01 7.35e-01
REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE 109 4.00e-01 4.66e-02 7.35e-01
REACTOME RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION 8 4.00e-01 -1.72e-01 7.35e-01
REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE 63 4.01e-01 6.12e-02 7.35e-01
REACTOME CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION 24 4.01e-01 9.90e-02 7.35e-01
REACTOME SIGNALING BY CSF3 G CSF 30 4.02e-01 8.84e-02 7.36e-01
REACTOME SEROTONIN NEUROTRANSMITTER RELEASE CYCLE 17 4.02e-01 -1.17e-01 7.36e-01
REACTOME SYNTHESIS OF PG 8 4.03e-01 1.71e-01 7.36e-01
REACTOME SUMOYLATION OF SUMOYLATION PROTEINS 35 4.03e-01 8.16e-02 7.36e-01
REACTOME SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER 15 4.04e-01 1.24e-01 7.36e-01
REACTOME SYNTHESIS OF DOLICHYL PHOSPHATE 6 4.07e-01 -1.96e-01 7.40e-01
REACTOME GRB7 EVENTS IN ERBB2 SIGNALING 5 4.08e-01 2.14e-01 7.40e-01
REACTOME PTEN REGULATION 135 4.08e-01 4.13e-02 7.40e-01
REACTOME SYNAPTIC ADHESION LIKE MOLECULES 19 4.08e-01 -1.10e-01 7.40e-01
REACTOME VITAMIN B5 PANTOTHENATE METABOLISM 16 4.09e-01 -1.19e-01 7.40e-01
REACTOME COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM 21 4.09e-01 1.04e-01 7.40e-01
REACTOME PHASE 3 RAPID REPOLARISATION 8 4.09e-01 -1.69e-01 7.40e-01
REACTOME SUMO IS TRANSFERRED FROM E1 TO E2 UBE2I UBC9 7 4.09e-01 1.80e-01 7.40e-01
REACTOME PEPTIDE LIGAND BINDING RECEPTORS 188 4.12e-01 -3.47e-02 7.43e-01
REACTOME TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT 18 4.12e-01 1.12e-01 7.43e-01
REACTOME NEUROFASCIN INTERACTIONS 6 4.12e-01 -1.93e-01 7.43e-01
REACTOME ASPIRIN ADME 42 4.13e-01 7.29e-02 7.43e-01
REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY 10 4.14e-01 -1.49e-01 7.43e-01
REACTOME REGULATION BY C FLIP 11 4.14e-01 1.42e-01 7.43e-01
REACTOME HYALURONAN UPTAKE AND DEGRADATION 12 4.15e-01 -1.36e-01 7.43e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA 27 4.15e-01 9.07e-02 7.43e-01
REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS 101 4.16e-01 4.68e-02 7.44e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES 16 4.19e-01 1.17e-01 7.48e-01
REACTOME CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER 25 4.19e-01 -9.34e-02 7.48e-01
REACTOME UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN 6 4.19e-01 1.90e-01 7.48e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA 25 4.20e-01 -9.32e-02 7.48e-01
REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION 26 4.21e-01 9.12e-02 7.49e-01
REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE 24 4.22e-01 9.47e-02 7.50e-01
REACTOME MHC CLASS II ANTIGEN PRESENTATION 121 4.24e-01 4.21e-02 7.52e-01
REACTOME COENZYME A BIOSYNTHESIS 8 4.24e-01 -1.63e-01 7.52e-01
REACTOME EXTRA NUCLEAR ESTROGEN SIGNALING 74 4.25e-01 -5.36e-02 7.53e-01
REACTOME MAPK FAMILY SIGNALING CASCADES 314 4.27e-01 2.60e-02 7.56e-01
REACTOME HORMONE LIGAND BINDING RECEPTORS 12 4.28e-01 -1.32e-01 7.56e-01
REACTOME FRUCTOSE CATABOLISM 5 4.28e-01 -2.05e-01 7.56e-01
REACTOME MASTL FACILITATES MITOTIC PROGRESSION 10 4.28e-01 1.45e-01 7.56e-01
REACTOME CHYLOMICRON CLEARANCE 5 4.29e-01 2.04e-01 7.56e-01
REACTOME G ALPHA Z SIGNALLING EVENTS 48 4.30e-01 -6.59e-02 7.56e-01
REACTOME HIV ELONGATION ARREST AND RECOVERY 33 4.34e-01 7.88e-02 7.61e-01
REACTOME SENSORY PROCESSING OF SOUND 72 4.34e-01 -5.34e-02 7.61e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1 25 4.34e-01 -9.03e-02 7.61e-01
REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES 29 4.35e-01 8.38e-02 7.61e-01
REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND 21 4.35e-01 -9.84e-02 7.61e-01
REACTOME TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION 5 4.36e-01 2.01e-01 7.62e-01
REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX 39 4.37e-01 7.20e-02 7.62e-01
REACTOME SUMOYLATION OF RNA BINDING PROTEINS 47 4.38e-01 6.54e-02 7.62e-01
REACTOME METABOLISM OF STEROID HORMONES 35 4.38e-01 -7.58e-02 7.62e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION 41 4.38e-01 7.00e-02 7.62e-01
REACTOME ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING 23 4.38e-01 -9.33e-02 7.63e-01
REACTOME INACTIVATION OF CSF3 G CSF SIGNALING 25 4.40e-01 8.92e-02 7.65e-01
REACTOME AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY 8 4.41e-01 -1.57e-01 7.65e-01
REACTOME HYALURONAN METABOLISM 17 4.41e-01 -1.08e-01 7.65e-01
REACTOME MELANIN BIOSYNTHESIS 5 4.42e-01 -1.99e-01 7.65e-01
REACTOME SIGNALING BY FGFR4 IN DISEASE 11 4.42e-01 -1.34e-01 7.65e-01
REACTOME SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS 74 4.44e-01 5.15e-02 7.66e-01
REACTOME ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT 23 4.44e-01 9.22e-02 7.66e-01
REACTOME DEATH RECEPTOR SIGNALING 143 4.44e-01 3.71e-02 7.66e-01
REACTOME VLDL CLEARANCE 6 4.45e-01 1.80e-01 7.66e-01
REACTOME SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL 25 4.45e-01 -8.82e-02 7.66e-01
REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS 16 4.46e-01 1.10e-01 7.66e-01
REACTOME PI5P REGULATES TP53 ACETYLATION 9 4.46e-01 1.47e-01 7.66e-01
REACTOME REGULATION OF BACH1 ACTIVITY 11 4.47e-01 1.33e-01 7.66e-01
REACTOME MAPK1 ERK2 ACTIVATION 9 4.47e-01 -1.46e-01 7.66e-01
REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT 31 4.48e-01 7.87e-02 7.67e-01
REACTOME DARPP 32 EVENTS 24 4.48e-01 8.94e-02 7.67e-01
REACTOME SUMOYLATION OF TRANSCRIPTION FACTORS 20 4.52e-01 9.72e-02 7.71e-01
REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION 10 4.52e-01 -1.37e-01 7.71e-01
REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING 13 4.54e-01 1.20e-01 7.73e-01
REACTOME SIGNAL ATTENUATION 10 4.54e-01 -1.37e-01 7.73e-01
REACTOME ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS 20 4.54e-01 9.66e-02 7.73e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES 8 4.56e-01 -1.52e-01 7.74e-01
REACTOME PP2A MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS 6 4.56e-01 1.76e-01 7.74e-01
REACTOME FCERI MEDIATED CA 2 MOBILIZATION 30 4.57e-01 -7.85e-02 7.75e-01
REACTOME AMINO ACID CONJUGATION 9 4.59e-01 1.43e-01 7.76e-01
REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS 30 4.59e-01 7.81e-02 7.76e-01
REACTOME SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS 12 4.59e-01 -1.23e-01 7.76e-01
REACTOME SUPPRESSION OF APOPTOSIS 7 4.59e-01 -1.62e-01 7.76e-01
REACTOME UREA CYCLE 9 4.60e-01 1.42e-01 7.76e-01
REACTOME SIGNALING BY NODAL 20 4.60e-01 9.53e-02 7.76e-01
REACTOME NEGATIVE REGULATION OF MAPK PATHWAY 41 4.61e-01 6.65e-02 7.77e-01
REACTOME PHASE 1 INACTIVATION OF FAST NA CHANNELS 6 4.62e-01 -1.73e-01 7.77e-01
REACTOME TRANSLESION SYNTHESIS BY POLH 19 4.62e-01 9.74e-02 7.77e-01
REACTOME XENOBIOTICS 22 4.64e-01 9.02e-02 7.79e-01
REACTOME INTERLEUKIN 35 SIGNALLING 12 4.65e-01 -1.22e-01 7.79e-01
REACTOME POLYMERASE SWITCHING 13 4.65e-01 1.17e-01 7.79e-01
REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX 9 4.66e-01 1.40e-01 7.79e-01
REACTOME NETRIN 1 SIGNALING 49 4.66e-01 -6.02e-02 7.79e-01
REACTOME LINOLEIC ACID LA METABOLISM 7 4.66e-01 -1.59e-01 7.79e-01
REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS 29 4.68e-01 7.79e-02 7.81e-01
REACTOME SIGNALING BY FGFR4 40 4.68e-01 6.63e-02 7.81e-01
REACTOME BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA 5 4.69e-01 1.87e-01 7.82e-01
REACTOME G ALPHA S SIGNALLING EVENTS 155 4.70e-01 -3.36e-02 7.82e-01
REACTOME GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION 30 4.72e-01 7.58e-02 7.84e-01
REACTOME NEUROTRANSMITTER CLEARANCE 9 4.74e-01 -1.38e-01 7.84e-01
REACTOME MITOCHONDRIAL BIOGENESIS 87 4.74e-01 4.44e-02 7.84e-01
REACTOME COMMON PATHWAY OF FIBRIN CLOT FORMATION 21 4.74e-01 -9.02e-02 7.84e-01
REACTOME RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION 6 4.74e-01 -1.69e-01 7.84e-01
REACTOME DEFECTS IN COBALAMIN B12 METABOLISM 13 4.75e-01 1.14e-01 7.84e-01
REACTOME METAL ION SLC TRANSPORTERS 23 4.75e-01 -8.61e-02 7.84e-01
REACTOME RAB GERANYLGERANYLATION 57 4.75e-01 5.47e-02 7.84e-01
REACTOME NECTIN NECL TRANS HETERODIMERIZATION 7 4.76e-01 -1.56e-01 7.84e-01
REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS 81 4.77e-01 -4.57e-02 7.84e-01
REACTOME DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA 77 4.78e-01 4.68e-02 7.84e-01
REACTOME CYTOSOLIC TRNA AMINOACYLATION 22 4.78e-01 8.74e-02 7.84e-01
REACTOME EPHB MEDIATED FORWARD SIGNALING 41 4.79e-01 6.39e-02 7.84e-01
REACTOME RHOA GTPASE CYCLE 142 4.79e-01 -3.44e-02 7.84e-01
REACTOME RORA ACTIVATES GENE EXPRESSION 17 4.79e-01 -9.91e-02 7.84e-01
REACTOME L1CAM INTERACTIONS 112 4.79e-01 -3.87e-02 7.84e-01
REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING 30 4.80e-01 7.45e-02 7.85e-01
REACTOME IRS MEDIATED SIGNALLING 47 4.80e-01 5.95e-02 7.85e-01
REACTOME MITOCHONDRIAL TRNA AMINOACYLATION 20 4.82e-01 9.09e-02 7.86e-01
REACTOME TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE 20 4.83e-01 9.07e-02 7.87e-01
REACTOME COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC 52 4.83e-01 -5.63e-02 7.87e-01
REACTOME NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10 12 4.84e-01 -1.17e-01 7.87e-01
REACTOME INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL 14 4.84e-01 1.08e-01 7.87e-01
REACTOME REGULATION OF IFNG SIGNALING 14 4.86e-01 -1.08e-01 7.87e-01
REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE 16 4.87e-01 1.00e-01 7.87e-01
REACTOME SIGNALING BY WNT IN CANCER 32 4.87e-01 -7.10e-02 7.87e-01
REACTOME CONJUGATION OF BENZOATE WITH GLYCINE 6 4.87e-01 -1.64e-01 7.87e-01
REACTOME G2 PHASE 5 4.88e-01 1.79e-01 7.87e-01
REACTOME PREDNISONE ADME 10 4.88e-01 1.27e-01 7.87e-01
REACTOME NEUTROPHIL DEGRANULATION 460 4.88e-01 -1.88e-02 7.87e-01
REACTOME DRUG ADME 103 4.89e-01 -3.95e-02 7.87e-01
REACTOME PKA ACTIVATION IN GLUCAGON SIGNALLING 17 4.89e-01 -9.69e-02 7.87e-01
REACTOME FRS MEDIATED FGFR1 SIGNALING 23 4.89e-01 8.33e-02 7.87e-01
REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE 9 4.89e-01 1.33e-01 7.87e-01
REACTOME CELL CELL JUNCTION ORGANIZATION 64 4.90e-01 -4.99e-02 7.87e-01
REACTOME SIGNALING BY RNF43 MUTANTS 8 4.91e-01 -1.41e-01 7.87e-01
REACTOME INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES 28 4.91e-01 -7.52e-02 7.87e-01
REACTOME RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES 16 4.91e-01 -9.94e-02 7.87e-01
REACTOME FBXW7 MUTANTS AND NOTCH1 IN CANCER 5 4.92e-01 1.77e-01 7.87e-01
REACTOME GLYCOGEN METABOLISM 22 4.94e-01 -8.43e-02 7.87e-01
REACTOME RHOBTB1 GTPASE CYCLE 22 4.94e-01 8.43e-02 7.87e-01
REACTOME NEF MEDIATED CD8 DOWN REGULATION 7 4.94e-01 1.49e-01 7.87e-01
REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE 5 4.95e-01 1.76e-01 7.87e-01
REACTOME ATORVASTATIN ADME 9 4.95e-01 -1.31e-01 7.87e-01
REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 44 4.95e-01 5.94e-02 7.87e-01
REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS 91 4.96e-01 -4.13e-02 7.87e-01
REACTOME GLUCONEOGENESIS 33 4.96e-01 6.85e-02 7.87e-01
REACTOME INNATE IMMUNE SYSTEM 1002 4.97e-01 1.27e-02 7.88e-01
REACTOME POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION 27 4.98e-01 7.53e-02 7.89e-01
REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION 19 4.98e-01 8.98e-02 7.89e-01
REACTOME METABOLISM OF COFACTORS 19 4.99e-01 8.95e-02 7.90e-01
REACTOME UPTAKE AND ACTIONS OF BACTERIAL TOXINS 28 5.00e-01 7.36e-02 7.90e-01
REACTOME ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS 10 5.01e-01 1.23e-01 7.90e-01
REACTOME PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING 11 5.02e-01 -1.17e-01 7.90e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR2 29 5.02e-01 7.21e-02 7.90e-01
REACTOME NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 24 5.03e-01 -7.91e-02 7.90e-01
REACTOME METABOLISM OF FAT SOLUBLE VITAMINS 46 5.03e-01 -5.71e-02 7.90e-01
REACTOME KILLING MECHANISMS 11 5.03e-01 1.17e-01 7.90e-01
REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER 77 5.04e-01 4.41e-02 7.90e-01
REACTOME BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA 5 5.04e-01 1.72e-01 7.90e-01
REACTOME INWARDLY RECTIFYING K CHANNELS 35 5.04e-01 -6.52e-02 7.90e-01
REACTOME RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK 47 5.05e-01 5.62e-02 7.91e-01
REACTOME SIGNALING BY NTRK3 TRKC 17 5.07e-01 -9.30e-02 7.92e-01
REACTOME RND3 GTPASE CYCLE 41 5.08e-01 -5.98e-02 7.93e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2 13 5.08e-01 1.06e-01 7.93e-01
REACTOME ESTABLISHMENT OF SISTER CHROMATID COHESION 9 5.10e-01 -1.27e-01 7.94e-01
REACTOME EARLY SARS COV 2 INFECTION EVENTS 34 5.10e-01 6.53e-02 7.94e-01
REACTOME ALPHA OXIDATION OF PHYTANATE 6 5.10e-01 1.55e-01 7.94e-01
REACTOME METABOLISM OF AMINE DERIVED HORMONES 17 5.11e-01 -9.21e-02 7.94e-01
REACTOME HSF1 DEPENDENT TRANSACTIVATION 37 5.11e-01 6.24e-02 7.94e-01
REACTOME SIGNALING BY HIPPO 19 5.11e-01 -8.70e-02 7.94e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL 14 5.12e-01 1.01e-01 7.94e-01
REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF 17 5.13e-01 9.17e-02 7.94e-01
REACTOME ERBB2 ACTIVATES PTK6 SIGNALING 13 5.13e-01 1.05e-01 7.94e-01
REACTOME P2Y RECEPTORS 9 5.14e-01 -1.26e-01 7.94e-01
REACTOME SYNTHESIS OF LIPOXINS LX 6 5.15e-01 1.54e-01 7.95e-01
REACTOME MISCELLANEOUS TRANSPORT AND BINDING EVENTS 24 5.17e-01 7.65e-02 7.97e-01
REACTOME MYOCLONIC EPILEPSY OF LAFORA 9 5.19e-01 1.24e-01 7.99e-01
REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION 10 5.19e-01 1.18e-01 7.99e-01
REACTOME LEISHMANIA INFECTION 156 5.19e-01 -2.99e-02 7.99e-01
REACTOME ERBB2 REGULATES CELL MOTILITY 15 5.21e-01 9.58e-02 8.01e-01
REACTOME MET ACTIVATES RAP1 AND RAC1 11 5.21e-01 -1.12e-01 8.01e-01
REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES 21 5.24e-01 -8.03e-02 8.04e-01
REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES 18 5.29e-01 -8.57e-02 8.08e-01
REACTOME SIGNALING BY MAPK MUTANTS 6 5.29e-01 1.48e-01 8.08e-01
REACTOME REGULATION OF BETA CELL DEVELOPMENT 41 5.29e-01 5.68e-02 8.08e-01
REACTOME FLT3 SIGNALING 38 5.29e-01 5.90e-02 8.08e-01
REACTOME TERMINAL PATHWAY OF COMPLEMENT 8 5.31e-01 1.28e-01 8.08e-01
REACTOME LIPOPHAGY 9 5.31e-01 1.21e-01 8.08e-01
REACTOME METHIONINE SALVAGE PATHWAY 6 5.31e-01 1.48e-01 8.08e-01
REACTOME PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1 9 5.31e-01 1.21e-01 8.08e-01
REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER 49 5.31e-01 5.17e-02 8.08e-01
REACTOME DISINHIBITION OF SNARE FORMATION 5 5.31e-01 1.62e-01 8.08e-01
REACTOME ER QUALITY CONTROL COMPARTMENT ERQC 21 5.33e-01 7.87e-02 8.09e-01
REACTOME TRANS GOLGI NETWORK VESICLE BUDDING 67 5.34e-01 4.39e-02 8.10e-01
REACTOME CARGO CONCENTRATION IN THE ER 32 5.35e-01 -6.34e-02 8.10e-01
REACTOME NEF AND SIGNAL TRANSDUCTION 8 5.35e-01 1.27e-01 8.10e-01
REACTOME COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC 98 5.35e-01 3.62e-02 8.10e-01
REACTOME DEFECTIVE RIPK1 MEDIATED REGULATED NECROSIS 7 5.37e-01 1.35e-01 8.12e-01
REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS 299 5.37e-01 2.07e-02 8.12e-01
REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS 13 5.38e-01 -9.86e-02 8.12e-01
REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION 19 5.38e-01 8.16e-02 8.12e-01
REACTOME ROLE OF ABL IN ROBO SLIT SIGNALING 8 5.39e-01 -1.26e-01 8.12e-01
REACTOME SIGNALING BY BMP 27 5.40e-01 -6.82e-02 8.12e-01
REACTOME CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN 45 5.40e-01 -5.28e-02 8.12e-01
REACTOME DEFENSINS 33 5.40e-01 -6.16e-02 8.12e-01
REACTOME CREB PHOSPHORYLATION 6 5.43e-01 -1.43e-01 8.16e-01
REACTOME RECYCLING OF BILE ACIDS AND SALTS 18 5.44e-01 -8.25e-02 8.16e-01
REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS 23 5.45e-01 7.29e-02 8.17e-01
REACTOME DEFECTIVE EXT2 CAUSES EXOSTOSES 2 12 5.46e-01 1.01e-01 8.18e-01
REACTOME DEFECTIVE GALNT3 CAUSES HFTC 16 5.49e-01 8.66e-02 8.21e-01
REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING 45 5.49e-01 -5.16e-02 8.21e-01
REACTOME MRNA EDITING 10 5.53e-01 1.08e-01 8.25e-01
REACTOME SIGNAL AMPLIFICATION 33 5.53e-01 -5.96e-02 8.25e-01
REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN 37 5.54e-01 -5.63e-02 8.25e-01
REACTOME FGFR1B LIGAND BINDING AND ACTIVATION 6 5.54e-01 -1.39e-01 8.25e-01
REACTOME GLUTAMATE AND GLUTAMINE METABOLISM 13 5.57e-01 9.41e-02 8.28e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG 7 5.58e-01 -1.28e-01 8.28e-01
REACTOME INTERLEUKIN 15 SIGNALING 13 5.58e-01 -9.39e-02 8.28e-01
REACTOME FRS MEDIATED FGFR2 SIGNALING 24 5.58e-01 6.90e-02 8.28e-01
REACTOME RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS 9 5.59e-01 1.12e-01 8.29e-01
REACTOME REGULATION OF SIGNALING BY CBL 22 5.60e-01 7.17e-02 8.30e-01
REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS 23 5.62e-01 -6.98e-02 8.32e-01
REACTOME METABOLISM OF FOLATE AND PTERINES 17 5.63e-01 8.10e-02 8.32e-01
REACTOME NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 11 5.63e-01 1.01e-01 8.32e-01
REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE 35 5.65e-01 5.62e-02 8.33e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3 11 5.65e-01 -1.00e-01 8.33e-01
REACTOME CHL1 INTERACTIONS 9 5.67e-01 -1.10e-01 8.35e-01
REACTOME ATTACHMENT OF GPI ANCHOR TO UPAR 7 5.68e-01 -1.25e-01 8.35e-01
REACTOME CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS 19 5.68e-01 7.57e-02 8.35e-01
REACTOME TYPE I HEMIDESMOSOME ASSEMBLY 11 5.68e-01 9.93e-02 8.35e-01
REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE 48 5.70e-01 -4.74e-02 8.36e-01
REACTOME SIGNALING BY FGFR1 IN DISEASE 38 5.71e-01 5.31e-02 8.36e-01
REACTOME UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION 19 5.71e-01 -7.50e-02 8.36e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1 20 5.71e-01 -7.31e-02 8.36e-01
REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN 76 5.72e-01 -3.75e-02 8.36e-01
REACTOME ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM 12 5.72e-01 -9.41e-02 8.36e-01
REACTOME BETA CATENIN INDEPENDENT WNT SIGNALING 145 5.73e-01 2.71e-02 8.36e-01
REACTOME METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION 15 5.75e-01 8.37e-02 8.38e-01
REACTOME EGFR DOWNREGULATION 30 5.76e-01 -5.90e-02 8.39e-01
REACTOME CELL JUNCTION ORGANIZATION 89 5.76e-01 -3.43e-02 8.39e-01
REACTOME NUCLEOTIDE BIOSYNTHESIS 14 5.77e-01 8.62e-02 8.39e-01
REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS 23 5.77e-01 6.72e-02 8.39e-01
REACTOME DEADENYLATION OF MRNA 25 5.80e-01 6.39e-02 8.41e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1 31 5.80e-01 5.74e-02 8.41e-01
REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS 9 5.80e-01 -1.06e-01 8.41e-01
REACTOME REGULATION OF MECP2 EXPRESSION AND ACTIVITY 30 5.81e-01 -5.83e-02 8.41e-01
REACTOME ERYTHROPOIETIN ACTIVATES STAT5 7 5.81e-01 -1.20e-01 8.41e-01
REACTOME ACTIVATION OF TRKA RECEPTORS 6 5.82e-01 -1.30e-01 8.41e-01
REACTOME GLUCOCORTICOID BIOSYNTHESIS 10 5.82e-01 -1.00e-01 8.41e-01
REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI 17 5.83e-01 7.70e-02 8.41e-01
REACTOME PIWI INTERACTING RNA PIRNA BIOGENESIS 29 5.83e-01 -5.88e-02 8.41e-01
REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX 32 5.84e-01 5.59e-02 8.41e-01
REACTOME ALPHA DEFENSINS 6 5.85e-01 -1.29e-01 8.41e-01
REACTOME NUCLEAR ENVELOPE NE REASSEMBLY 74 5.86e-01 3.66e-02 8.41e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING 5 5.86e-01 -1.41e-01 8.41e-01
REACTOME METABOLISM OF PORPHYRINS 26 5.87e-01 -6.16e-02 8.41e-01
REACTOME AUTOPHAGY 144 5.87e-01 2.62e-02 8.41e-01
REACTOME SIGNALING BY NOTCH1 T 7 9 NOTCH1 M1580 K2555 TRANSLOCATION MUTANT 7 5.87e-01 1.19e-01 8.41e-01
REACTOME MET ACTIVATES PTPN11 5 5.88e-01 -1.40e-01 8.41e-01
REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS 51 5.90e-01 4.36e-02 8.44e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH PI3K 6 5.92e-01 -1.26e-01 8.46e-01
REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES 34 5.94e-01 5.28e-02 8.48e-01
REACTOME APOPTOTIC EXECUTION PHASE 49 5.96e-01 4.38e-02 8.50e-01
REACTOME REGULATION OF PTEN MRNA TRANSLATION 9 5.97e-01 -1.02e-01 8.50e-01
REACTOME PARASITE INFECTION 57 5.97e-01 4.04e-02 8.50e-01
REACTOME BUDDING AND MATURATION OF HIV VIRION 28 5.98e-01 5.76e-02 8.50e-01
REACTOME ACTIVATION OF RAS IN B CELLS 5 5.98e-01 -1.36e-01 8.50e-01
REACTOME SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS 14 5.99e-01 8.12e-02 8.51e-01
REACTOME INTERLEUKIN 1 FAMILY SIGNALING 146 6.00e-01 2.52e-02 8.51e-01
REACTOME SIGNALING BY FGFR3 39 6.02e-01 4.83e-02 8.52e-01
REACTOME DISEASES OF DNA REPAIR 51 6.02e-01 4.22e-02 8.52e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS 11 6.02e-01 -9.08e-02 8.52e-01
REACTOME OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS 8 6.06e-01 -1.05e-01 8.57e-01
REACTOME PROLACTIN RECEPTOR SIGNALING 15 6.08e-01 -7.66e-02 8.58e-01
REACTOME SARS COV 2 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS 12 6.08e-01 8.56e-02 8.58e-01
REACTOME RAS SIGNALING DOWNSTREAM OF NF1 LOSS OF FUNCTION VARIANTS 7 6.09e-01 -1.12e-01 8.58e-01
REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS 11 6.09e-01 8.92e-02 8.58e-01
REACTOME ARACHIDONATE PRODUCTION FROM DAG 5 6.10e-01 -1.32e-01 8.60e-01
REACTOME ERYTHROPOIETIN ACTIVATES RAS 14 6.12e-01 -7.82e-02 8.61e-01
REACTOME SULFIDE OXIDATION TO SULFATE 6 6.12e-01 -1.19e-01 8.61e-01
REACTOME TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX 10 6.13e-01 9.23e-02 8.61e-01
REACTOME SYNDECAN INTERACTIONS 26 6.14e-01 -5.71e-02 8.62e-01
REACTOME CHOLESTEROL BIOSYNTHESIS 25 6.15e-01 -5.81e-02 8.62e-01
REACTOME VITAMIN B1 THIAMIN METABOLISM 5 6.15e-01 -1.30e-01 8.62e-01
REACTOME RHOB GTPASE CYCLE 67 6.20e-01 -3.50e-02 8.65e-01
REACTOME GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION 7 6.20e-01 -1.08e-01 8.65e-01
REACTOME IKBA VARIANT LEADS TO EDA ID 6 6.21e-01 1.17e-01 8.65e-01
REACTOME SUMOYLATION OF IMMUNE RESPONSE PROTEINS 10 6.21e-01 9.04e-02 8.65e-01
REACTOME SIGNALING BY SCF KIT 42 6.21e-01 4.41e-02 8.65e-01
REACTOME TRAF6 MEDIATED NF KB ACTIVATION 24 6.21e-01 5.83e-02 8.65e-01
REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION 11 6.21e-01 8.61e-02 8.65e-01
REACTOME TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS 36 6.22e-01 4.75e-02 8.65e-01
REACTOME TP53 REGULATES METABOLIC GENES 81 6.23e-01 3.16e-02 8.66e-01
REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES 77 6.24e-01 -3.23e-02 8.66e-01
REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4 33 6.24e-01 -4.93e-02 8.66e-01
REACTOME AMINE LIGAND BINDING RECEPTORS 40 6.26e-01 -4.45e-02 8.66e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX 91 6.27e-01 -2.95e-02 8.66e-01
REACTOME TRANSCRIPTIONAL REGULATION BY MECP2 60 6.27e-01 -3.62e-02 8.66e-01
REACTOME REGULATION OF NF KAPPA B SIGNALING 17 6.28e-01 6.79e-02 8.66e-01
REACTOME P75NTR REGULATES AXONOGENESIS 9 6.28e-01 -9.32e-02 8.66e-01
REACTOME BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA 17 6.28e-01 6.78e-02 8.66e-01
REACTOME GPVI MEDIATED ACTIVATION CASCADE 35 6.29e-01 4.73e-02 8.66e-01
REACTOME FGFR2B LIGAND BINDING AND ACTIVATION 10 6.29e-01 8.83e-02 8.66e-01
REACTOME CALNEXIN CALRETICULIN CYCLE 26 6.29e-01 5.48e-02 8.66e-01
REACTOME ESTROGEN BIOSYNTHESIS 6 6.31e-01 1.13e-01 8.68e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION TERMINATION 23 6.31e-01 5.78e-02 8.68e-01
REACTOME ANCHORING FIBRIL FORMATION 13 6.32e-01 -7.67e-02 8.68e-01
REACTOME INSULIN RECEPTOR SIGNALLING CASCADE 53 6.34e-01 3.78e-02 8.69e-01
REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION 183 6.34e-01 -2.04e-02 8.69e-01
REACTOME CAMK IV MEDIATED PHOSPHORYLATION OF CREB 10 6.35e-01 -8.67e-02 8.69e-01
REACTOME REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR 11 6.35e-01 8.25e-02 8.69e-01
REACTOME INTERLEUKIN 9 SIGNALING 7 6.36e-01 -1.03e-01 8.69e-01
REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING 6 6.36e-01 1.12e-01 8.69e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING 5 6.37e-01 -1.22e-01 8.69e-01
REACTOME DEFECTIVE CHSY1 CAUSES TPBS 7 6.37e-01 1.03e-01 8.69e-01
REACTOME TELOMERE EXTENSION BY TELOMERASE 22 6.37e-01 5.80e-02 8.69e-01
REACTOME METABOLISM OF NUCLEOTIDES 94 6.38e-01 -2.81e-02 8.69e-01
REACTOME REGULATION OF TP53 EXPRESSION AND DEGRADATION 37 6.41e-01 4.44e-02 8.71e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12 22 6.42e-01 -5.73e-02 8.71e-01
REACTOME SUMOYLATION OF INTRACELLULAR RECEPTORS 29 6.42e-01 -4.99e-02 8.71e-01
REACTOME TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX 14 6.42e-01 7.18e-02 8.71e-01
REACTOME PLASMA LIPOPROTEIN REMODELING 33 6.42e-01 -4.68e-02 8.71e-01
REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS 12 6.43e-01 -7.74e-02 8.71e-01
REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 19 6.43e-01 6.14e-02 8.71e-01
REACTOME GLYCOSPHINGOLIPID METABOLISM 39 6.44e-01 -4.27e-02 8.72e-01
REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE 52 6.45e-01 3.70e-02 8.72e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST 14 6.47e-01 7.08e-02 8.73e-01
REACTOME O LINKED GLYCOSYLATION OF MUCINS 61 6.47e-01 -3.39e-02 8.73e-01
REACTOME PURINE CATABOLISM 17 6.47e-01 6.41e-02 8.73e-01
REACTOME ARMS MEDIATED ACTIVATION 7 6.49e-01 -9.93e-02 8.73e-01
REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC 198 6.49e-01 1.88e-02 8.73e-01
REACTOME RHOH GTPASE CYCLE 37 6.50e-01 4.31e-02 8.73e-01
REACTOME SIGNALING BY CSF1 M CSF IN MYELOID CELLS 30 6.50e-01 4.79e-02 8.73e-01
REACTOME PEPTIDE HORMONE BIOSYNTHESIS 13 6.50e-01 7.26e-02 8.73e-01
REACTOME SCAVENGING BY CLASS B RECEPTORS 6 6.50e-01 1.07e-01 8.73e-01
REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON 17 6.50e-01 6.35e-02 8.73e-01
REACTOME ETHANOL OXIDATION 12 6.52e-01 -7.51e-02 8.73e-01
REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK 111 6.53e-01 2.47e-02 8.73e-01
REACTOME OVARIAN TUMOR DOMAIN PROTEASES 36 6.54e-01 -4.31e-02 8.73e-01
REACTOME RESPONSE TO METAL IONS 14 6.54e-01 6.91e-02 8.73e-01
REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING 13 6.55e-01 -7.16e-02 8.73e-01
REACTOME P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1 6 6.55e-01 1.05e-01 8.73e-01
REACTOME UPTAKE OF DIETARY COBALAMINS INTO ENTEROCYTES 9 6.55e-01 8.60e-02 8.73e-01
REACTOME IRAK1 RECRUITS IKK COMPLEX 12 6.55e-01 7.44e-02 8.73e-01
REACTOME PROCESSING OF SMDT1 16 6.56e-01 6.44e-02 8.73e-01
REACTOME NOTCH HLH TRANSCRIPTION PATHWAY 24 6.56e-01 -5.25e-02 8.73e-01
REACTOME DOWNREGULATION OF ERBB4 SIGNALING 9 6.58e-01 8.52e-02 8.73e-01
REACTOME PTK6 PROMOTES HIF1A STABILIZATION 6 6.58e-01 -1.04e-01 8.73e-01
REACTOME SCAVENGING BY CLASS F RECEPTORS 6 6.59e-01 1.04e-01 8.73e-01
REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS 46 6.59e-01 -3.76e-02 8.73e-01
REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING 26 6.60e-01 4.99e-02 8.73e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS 12 6.60e-01 -7.34e-02 8.73e-01
REACTOME INTRAFLAGELLAR TRANSPORT 50 6.61e-01 3.59e-02 8.73e-01
REACTOME RHO GTPASES ACTIVATE NADPH OXIDASES 21 6.61e-01 -5.53e-02 8.73e-01
REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY 23 6.63e-01 5.25e-02 8.74e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS 15 6.63e-01 -6.50e-02 8.74e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS 14 6.63e-01 -6.73e-02 8.74e-01
REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL 12 6.64e-01 7.25e-02 8.74e-01
REACTOME RUNX3 REGULATES CDKN1A TRANSCRIPTION 7 6.65e-01 9.45e-02 8.74e-01
REACTOME INTERACTION BETWEEN L1 AND ANKYRINS 30 6.65e-01 4.56e-02 8.74e-01
REACTOME EFFECTS OF PIP2 HYDROLYSIS 26 6.65e-01 -4.90e-02 8.74e-01
REACTOME GDP FUCOSE BIOSYNTHESIS 6 6.66e-01 -1.02e-01 8.74e-01
REACTOME DECTIN 2 FAMILY 26 6.66e-01 4.89e-02 8.74e-01
REACTOME EICOSANOID LIGAND BINDING RECEPTORS 14 6.67e-01 -6.63e-02 8.75e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER 28 6.69e-01 4.67e-02 8.77e-01
REACTOME DEFECTIVE CHST3 CAUSES SEDCJD 7 6.70e-01 9.31e-02 8.77e-01
REACTOME VITAMIN D CALCIFEROL METABOLISM 12 6.70e-01 7.10e-02 8.77e-01
REACTOME PHENYLALANINE METABOLISM 6 6.72e-01 9.99e-02 8.77e-01
REACTOME G2 M DNA REPLICATION CHECKPOINT 5 6.72e-01 1.09e-01 8.77e-01
REACTOME INTERLEUKIN 36 PATHWAY 7 6.72e-01 -9.24e-02 8.77e-01
REACTOME CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE 49 6.73e-01 3.49e-02 8.77e-01
REACTOME RECYCLING PATHWAY OF L1 43 6.73e-01 3.71e-02 8.77e-01
REACTOME STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS 10 6.74e-01 7.69e-02 8.77e-01
REACTOME BETA DEFENSINS 27 6.75e-01 -4.66e-02 8.78e-01
REACTOME DISEASES OF CARBOHYDRATE METABOLISM 31 6.75e-01 -4.35e-02 8.78e-01
REACTOME RAF INDEPENDENT MAPK1 3 ACTIVATION 22 6.79e-01 5.10e-02 8.81e-01
REACTOME TRANSPORT OF NUCLEOTIDE SUGARS 8 6.79e-01 8.45e-02 8.81e-01
REACTOME PYRIMIDINE CATABOLISM 12 6.80e-01 -6.88e-02 8.81e-01
REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS 43 6.80e-01 3.64e-02 8.81e-01
REACTOME FCGR ACTIVATION 11 6.81e-01 -7.16e-02 8.82e-01
REACTOME RHOF GTPASE CYCLE 40 6.82e-01 -3.75e-02 8.82e-01
REACTOME HDL REMODELING 10 6.83e-01 7.45e-02 8.82e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH CDC42 19 6.83e-01 -5.41e-02 8.82e-01
REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP 41 6.84e-01 -3.68e-02 8.82e-01
REACTOME RUNX3 REGULATES BCL2L11 BIM TRANSCRIPTION 5 6.84e-01 -1.05e-01 8.82e-01
REACTOME SEROTONIN RECEPTORS 11 6.84e-01 -7.08e-02 8.82e-01
REACTOME PLATELET SENSITIZATION BY LDL 17 6.84e-01 5.69e-02 8.82e-01
REACTOME CS DS DEGRADATION 12 6.86e-01 -6.75e-02 8.82e-01
REACTOME TRIGLYCERIDE BIOSYNTHESIS 12 6.86e-01 6.74e-02 8.82e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS 15 6.88e-01 -5.99e-02 8.83e-01
REACTOME REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS 11 6.88e-01 -6.99e-02 8.83e-01
REACTOME SIGNALING BY EGFR 49 6.89e-01 -3.30e-02 8.84e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K 12 6.92e-01 -6.60e-02 8.88e-01
REACTOME RHO GTPASES ACTIVATE ROCKS 19 6.93e-01 -5.23e-02 8.88e-01
REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY 29 6.94e-01 4.22e-02 8.88e-01
REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS 83 6.98e-01 -2.46e-02 8.93e-01
REACTOME VLDLR INTERNALISATION AND DEGRADATION 16 7.00e-01 5.57e-02 8.94e-01
REACTOME TRIF MEDIATED PROGRAMMED CELL DEATH 9 7.02e-01 -7.37e-02 8.95e-01
REACTOME RAB REGULATION OF TRAFFICKING 110 7.02e-01 -2.11e-02 8.95e-01
REACTOME TRANSPORT AND SYNTHESIS OF PAPS 6 7.03e-01 8.99e-02 8.95e-01
REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX 21 7.04e-01 -4.80e-02 8.95e-01
REACTOME CD163 MEDIATING AN ANTI INFLAMMATORY RESPONSE 9 7.04e-01 -7.32e-02 8.95e-01
REACTOME ASSEMBLY OF THE HIV VIRION 16 7.04e-01 5.49e-02 8.95e-01
REACTOME ATTACHMENT AND ENTRY 16 7.04e-01 -5.48e-02 8.95e-01
REACTOME RUNX3 REGULATES P14 ARF 10 7.05e-01 6.92e-02 8.95e-01
REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE 30 7.05e-01 -3.99e-02 8.95e-01
REACTOME RHOT1 GTPASE CYCLE 5 7.08e-01 -9.67e-02 8.98e-01
REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS 16 7.09e-01 5.39e-02 8.98e-01
REACTOME MISMATCH REPAIR 15 7.11e-01 -5.53e-02 9.00e-01
REACTOME MATURATION OF PROTEIN 3A 9 7.12e-01 -7.10e-02 9.01e-01
REACTOME CHREBP ACTIVATES METABOLIC GENE EXPRESSION 8 7.13e-01 -7.51e-02 9.01e-01
REACTOME TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE 10 7.15e-01 -6.67e-02 9.03e-01
REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS 6 7.17e-01 8.53e-02 9.05e-01
REACTOME INTERLEUKIN 17 SIGNALING 66 7.21e-01 2.55e-02 9.08e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS 5 7.21e-01 9.23e-02 9.08e-01
REACTOME CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND 9 7.23e-01 -6.83e-02 9.09e-01
REACTOME LATE SARS COV 2 INFECTION EVENTS 67 7.23e-01 -2.50e-02 9.09e-01
REACTOME DOWNREGULATION OF ERBB2 SIGNALING 29 7.23e-01 3.80e-02 9.09e-01
REACTOME FORMATION OF XYLULOSE 5 PHOSPHATE 5 7.25e-01 9.08e-02 9.10e-01
REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE 17 7.25e-01 -4.92e-02 9.10e-01
REACTOME REGULATION OF NPAS4 GENE EXPRESSION 13 7.26e-01 -5.62e-02 9.10e-01
REACTOME SULFUR AMINO ACID METABOLISM 27 7.26e-01 3.89e-02 9.10e-01
REACTOME LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME 11 7.30e-01 6.01e-02 9.14e-01
REACTOME INTERLEUKIN 23 SIGNALING 9 7.30e-01 6.63e-02 9.14e-01
REACTOME VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS 42 7.33e-01 -3.05e-02 9.16e-01
REACTOME IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS 17 7.33e-01 4.78e-02 9.16e-01
REACTOME REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS 7 7.37e-01 -7.34e-02 9.18e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS 34 7.39e-01 3.31e-02 9.18e-01
REACTOME INTERLEUKIN 6 SIGNALING 11 7.39e-01 5.80e-02 9.18e-01
REACTOME SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA PHE 6 7.39e-01 7.84e-02 9.18e-01
REACTOME DIGESTION OF DIETARY CARBOHYDRATE 6 7.40e-01 -7.83e-02 9.18e-01
REACTOME ASPARAGINE N LINKED GLYCOSYLATION 299 7.40e-01 -1.12e-02 9.18e-01
REACTOME GLUTATHIONE CONJUGATION 33 7.40e-01 -3.33e-02 9.18e-01
REACTOME ACTIVATION OF AMPK DOWNSTREAM OF NMDARS 28 7.41e-01 -3.61e-02 9.18e-01
REACTOME INITIATION OF NUCLEAR ENVELOPE NE REFORMATION 18 7.41e-01 4.49e-02 9.18e-01
REACTOME GP1B IX V ACTIVATION SIGNALLING 11 7.42e-01 -5.74e-02 9.18e-01
REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR 24 7.42e-01 -3.89e-02 9.18e-01
REACTOME NEUROTRANSMITTER RELEASE CYCLE 48 7.43e-01 2.73e-02 9.18e-01
REACTOME GRB2 EVENTS IN ERBB2 SIGNALING 16 7.43e-01 -4.73e-02 9.18e-01
REACTOME PEROXISOMAL LIPID METABOLISM 28 7.44e-01 3.57e-02 9.18e-01
REACTOME CGMP EFFECTS 16 7.44e-01 -4.71e-02 9.18e-01
REACTOME NR1H2 AND NR1H3 MEDIATED SIGNALING 46 7.44e-01 -2.78e-02 9.18e-01
REACTOME SPHINGOLIPID METABOLISM 84 7.45e-01 -2.05e-02 9.18e-01
REACTOME DEFECTIVE F9 ACTIVATION 5 7.46e-01 -8.38e-02 9.18e-01
REACTOME TYSND1 CLEAVES PEROXISOMAL PROTEINS 7 7.46e-01 -7.08e-02 9.18e-01
REACTOME REGULATION OF PTEN LOCALIZATION 8 7.46e-01 6.62e-02 9.18e-01
REACTOME SIGNALING BY MRAS COMPLEX MUTANTS 7 7.46e-01 -7.06e-02 9.18e-01
REACTOME COBALAMIN CBL METABOLISM 7 7.47e-01 7.05e-02 9.18e-01
REACTOME SHC1 EVENTS IN ERBB4 SIGNALING 14 7.47e-01 -4.97e-02 9.18e-01
REACTOME MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION 15 7.48e-01 4.79e-02 9.18e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS 8 7.49e-01 -6.52e-02 9.19e-01
REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION 8 7.50e-01 -6.50e-02 9.19e-01
REACTOME VESICLE MEDIATED TRANSPORT 642 7.50e-01 -7.36e-03 9.19e-01
REACTOME GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER 25 7.51e-01 3.67e-02 9.19e-01
REACTOME POTENTIAL THERAPEUTICS FOR SARS 92 7.55e-01 1.88e-02 9.23e-01
REACTOME DOWNSTREAM SIGNAL TRANSDUCTION 29 7.56e-01 -3.34e-02 9.23e-01
REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX 15 7.56e-01 -4.64e-02 9.23e-01
REACTOME RNA POLYMERASE III CHAIN ELONGATION 18 7.57e-01 4.22e-02 9.23e-01
REACTOME SIGNALING BY LEPTIN 11 7.58e-01 5.36e-02 9.24e-01
REACTOME N GLYCAN ANTENNAE ELONGATION 15 7.59e-01 -4.57e-02 9.25e-01
REACTOME TIGHT JUNCTION INTERACTIONS 29 7.60e-01 3.27e-02 9.25e-01
REACTOME MAP2K AND MAPK ACTIVATION 38 7.61e-01 -2.85e-02 9.25e-01
REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY 15 7.61e-01 4.53e-02 9.25e-01
REACTOME DCC MEDIATED ATTRACTIVE SIGNALING 14 7.61e-01 -4.69e-02 9.25e-01
REACTOME ERKS ARE INACTIVATED 13 7.62e-01 4.85e-02 9.25e-01
REACTOME DEFECTIVE LFNG CAUSES SCDO3 5 7.64e-01 -7.77e-02 9.25e-01
REACTOME CD28 DEPENDENT VAV1 PATHWAY 11 7.64e-01 -5.23e-02 9.25e-01
REACTOME ABACAVIR ADME 9 7.64e-01 -5.78e-02 9.25e-01
REACTOME ROBO RECEPTORS BIND AKAP5 9 7.64e-01 -5.78e-02 9.25e-01
REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS 6 7.65e-01 7.05e-02 9.25e-01
REACTOME INTERLEUKIN 10 SIGNALING 43 7.65e-01 2.63e-02 9.25e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH RAS 9 7.67e-01 -5.71e-02 9.25e-01
REACTOME BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA 6 7.67e-01 6.99e-02 9.25e-01
REACTOME OTHER INTERLEUKIN SIGNALING 24 7.67e-01 -3.49e-02 9.25e-01
REACTOME PREGNENOLONE BIOSYNTHESIS 12 7.68e-01 -4.91e-02 9.25e-01
REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS 15 7.69e-01 -4.39e-02 9.25e-01
REACTOME GLYCOGEN STORAGE DISEASES 15 7.69e-01 4.38e-02 9.25e-01
REACTOME KSRP KHSRP BINDS AND DESTABILIZES MRNA 17 7.72e-01 4.06e-02 9.28e-01
REACTOME CA2 ACTIVATED K CHANNELS 9 7.72e-01 5.57e-02 9.28e-01
REACTOME SIGNALING BY PDGFR IN DISEASE 20 7.74e-01 -3.71e-02 9.28e-01
REACTOME SHC1 EVENTS IN ERBB2 SIGNALING 22 7.74e-01 -3.54e-02 9.28e-01
REACTOME RRNA PROCESSING IN THE MITOCHONDRION 9 7.76e-01 -5.48e-02 9.30e-01
REACTOME RAC3 GTPASE CYCLE 85 7.78e-01 -1.77e-02 9.31e-01
REACTOME MICRORNA MIRNA BIOGENESIS 25 7.78e-01 3.26e-02 9.31e-01
REACTOME METABOLISM OF STEROIDS 150 7.80e-01 -1.32e-02 9.32e-01
REACTOME CRMPS IN SEMA3A SIGNALING 15 7.80e-01 -4.16e-02 9.32e-01
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES 55 7.80e-01 -2.17e-02 9.32e-01
REACTOME TRANSCRIPTIONAL REGULATION BY E2F6 32 7.81e-01 -2.84e-02 9.32e-01
REACTOME HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS 7 7.83e-01 6.02e-02 9.33e-01
REACTOME BASIGIN INTERACTIONS 24 7.83e-01 -3.24e-02 9.33e-01
REACTOME LDL CLEARANCE 19 7.86e-01 3.59e-02 9.35e-01
REACTOME TBC RABGAPS 40 7.87e-01 2.47e-02 9.35e-01
REACTOME PURINE SALVAGE 12 7.87e-01 4.51e-02 9.35e-01
REACTOME NETRIN MEDIATED REPULSION SIGNALS 8 7.87e-01 -5.51e-02 9.35e-01
REACTOME CYTOCHROME C MEDIATED APOPTOTIC RESPONSE 12 7.96e-01 4.32e-02 9.45e-01
REACTOME VEGF LIGAND RECEPTOR INTERACTIONS 7 7.96e-01 5.63e-02 9.45e-01
REACTOME NEGATIVE REGULATION OF ACTIVITY OF TFAP2 AP 2 FAMILY TRANSCRIPTION FACTORS 10 7.97e-01 4.70e-02 9.45e-01
REACTOME SIGNALING BY LRP5 MUTANTS 6 7.98e-01 -6.02e-02 9.45e-01
REACTOME MAPK3 ERK1 ACTIVATION 10 7.98e-01 -4.67e-02 9.45e-01
REACTOME INTRA GOLGI TRAFFIC 43 7.99e-01 -2.24e-02 9.45e-01
REACTOME ARACHIDONIC ACID METABOLISM 57 7.99e-01 -1.95e-02 9.45e-01
REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN 19 8.00e-01 -3.36e-02 9.45e-01
REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES 12 8.02e-01 4.19e-02 9.45e-01
REACTOME MULTIFUNCTIONAL ANION EXCHANGERS 9 8.02e-01 -4.83e-02 9.45e-01
REACTOME TYROSINE CATABOLISM 5 8.02e-01 -6.47e-02 9.45e-01
REACTOME ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS 5 8.06e-01 6.35e-02 9.49e-01
REACTOME NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION 20 8.07e-01 -3.16e-02 9.49e-01
REACTOME REGULATED PROTEOLYSIS OF P75NTR 11 8.09e-01 4.21e-02 9.49e-01
REACTOME MYOGENESIS 29 8.09e-01 2.59e-02 9.49e-01
REACTOME ASPARTATE AND ASPARAGINE METABOLISM 11 8.09e-01 -4.20e-02 9.49e-01
REACTOME TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS 29 8.10e-01 2.58e-02 9.49e-01
REACTOME GAP JUNCTION DEGRADATION 12 8.11e-01 3.99e-02 9.49e-01
REACTOME SIGNALING BY FLT3 FUSION PROTEINS 19 8.12e-01 -3.16e-02 9.49e-01
REACTOME ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING 9 8.12e-01 -4.59e-02 9.49e-01
REACTOME CHOLINE CATABOLISM 6 8.12e-01 5.62e-02 9.49e-01
REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY 51 8.12e-01 1.93e-02 9.49e-01
REACTOME RECEPTOR MEDIATED MITOPHAGY 10 8.12e-01 4.34e-02 9.49e-01
REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS 93 8.13e-01 1.42e-02 9.49e-01
REACTOME DISSOLUTION OF FIBRIN CLOT 13 8.15e-01 -3.74e-02 9.49e-01
REACTOME CALCITONIN LIKE LIGAND RECEPTORS 10 8.15e-01 4.26e-02 9.49e-01
REACTOME ACYL CHAIN REMODELING OF CL 5 8.16e-01 6.02e-02 9.49e-01
REACTOME RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES TREGS 9 8.16e-01 4.48e-02 9.49e-01
REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION 23 8.16e-01 -2.80e-02 9.49e-01
REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS 19 8.16e-01 3.08e-02 9.49e-01
REACTOME SYNTHESIS OF 12 EICOSATETRAENOIC ACID DERIVATIVES 7 8.19e-01 5.00e-02 9.51e-01
REACTOME SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA 52 8.19e-01 -1.83e-02 9.51e-01
REACTOME PI3K EVENTS IN ERBB4 SIGNALING 10 8.20e-01 4.16e-02 9.51e-01
REACTOME NEF MEDIATED CD4 DOWN REGULATION 9 8.21e-01 -4.36e-02 9.51e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH PI3K 7 8.21e-01 -4.94e-02 9.51e-01
REACTOME TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS 52 8.22e-01 1.81e-02 9.51e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION 29 8.22e-01 -2.41e-02 9.51e-01
REACTOME SIGNALING BY NOTCH3 48 8.25e-01 1.85e-02 9.53e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY 19 8.25e-01 -2.93e-02 9.53e-01
REACTOME ANTIMICROBIAL PEPTIDES 76 8.25e-01 -1.47e-02 9.53e-01
REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS 18 8.26e-01 -2.99e-02 9.53e-01
REACTOME ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA 9 8.26e-01 -4.22e-02 9.53e-01
REACTOME FORMATION OF APOPTOSOME 10 8.28e-01 3.97e-02 9.53e-01
REACTOME SYNTHESIS OF PIPS AT THE ER MEMBRANE 5 8.28e-01 5.60e-02 9.53e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD4 15 8.29e-01 -3.22e-02 9.53e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE 5 8.29e-01 -5.57e-02 9.53e-01
REACTOME RRNA MODIFICATION IN THE MITOCHONDRION 6 8.31e-01 -5.03e-02 9.55e-01
REACTOME SIGNALING BY ERBB2 IN CANCER 26 8.32e-01 2.40e-02 9.55e-01
REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS 28 8.33e-01 -2.30e-02 9.55e-01
REACTOME G PROTEIN ACTIVATION 24 8.34e-01 -2.47e-02 9.55e-01
REACTOME MATURATION OF SARS COV 1 SPIKE PROTEIN 5 8.34e-01 5.41e-02 9.55e-01
REACTOME TRIGLYCERIDE METABOLISM 35 8.34e-01 2.05e-02 9.55e-01
REACTOME METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS 122 8.36e-01 1.09e-02 9.56e-01
REACTOME PROPIONYL COA CATABOLISM 5 8.37e-01 5.32e-02 9.57e-01
REACTOME INTEGRIN SIGNALING 27 8.38e-01 -2.28e-02 9.57e-01
REACTOME CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY 25 8.39e-01 -2.35e-02 9.57e-01
REACTOME REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS 15 8.39e-01 3.03e-02 9.57e-01
REACTOME RUNX3 REGULATES NOTCH SIGNALING 13 8.40e-01 -3.24e-02 9.57e-01
REACTOME AMINO ACIDS REGULATE MTORC1 53 8.42e-01 1.58e-02 9.57e-01
REACTOME WAX AND PLASMALOGEN BIOSYNTHESIS 5 8.42e-01 -5.14e-02 9.57e-01
REACTOME MATURATION OF SARS COV 2 NUCLEOPROTEIN 15 8.42e-01 -2.97e-02 9.57e-01
REACTOME ER TO GOLGI ANTEROGRADE TRANSPORT 152 8.43e-01 -9.30e-03 9.57e-01
REACTOME ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY 5 8.43e-01 5.10e-02 9.57e-01
REACTOME PEPTIDE HORMONE METABOLISM 84 8.44e-01 1.24e-02 9.57e-01
REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS 16 8.44e-01 -2.83e-02 9.57e-01
REACTOME WNT MEDIATED ACTIVATION OF DVL 8 8.45e-01 3.98e-02 9.57e-01
REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION 12 8.46e-01 3.25e-02 9.57e-01
REACTOME SIGNALING BY FGFR1 49 8.46e-01 1.61e-02 9.57e-01
REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE 15 8.48e-01 2.85e-02 9.57e-01
REACTOME MOLYBDENUM COFACTOR BIOSYNTHESIS 6 8.48e-01 4.51e-02 9.57e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION 27 8.48e-01 -2.12e-02 9.57e-01
REACTOME PLATELET AGGREGATION PLUG FORMATION 39 8.49e-01 -1.76e-02 9.57e-01
REACTOME REGULATION OF PTEN GENE TRANSCRIPTION 59 8.50e-01 1.42e-02 9.57e-01
REACTOME REGULATION OF IFNA IFNB SIGNALING 23 8.50e-01 -2.27e-02 9.57e-01
REACTOME PI3K AKT SIGNALING IN CANCER 103 8.50e-01 1.07e-02 9.57e-01
REACTOME IRE1ALPHA ACTIVATES CHAPERONES 48 8.52e-01 -1.56e-02 9.57e-01
REACTOME PYRUVATE METABOLISM 29 8.52e-01 2.00e-02 9.57e-01
REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB 5 8.53e-01 4.79e-02 9.57e-01
REACTOME CTLA4 INHIBITORY SIGNALING 21 8.53e-01 2.33e-02 9.57e-01
REACTOME DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B 7 8.54e-01 -4.03e-02 9.57e-01
REACTOME REGULATION OF NPAS4 GENE TRANSCRIPTION 5 8.54e-01 4.75e-02 9.57e-01
REACTOME ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS 41 8.55e-01 -1.65e-02 9.57e-01
REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR 19 8.56e-01 2.40e-02 9.57e-01
REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE 17 8.56e-01 2.54e-02 9.57e-01
REACTOME SARS COV 2 TARGETS PDZ PROTEINS IN CELL CELL JUNCTION 5 8.57e-01 -4.67e-02 9.57e-01
REACTOME IRAK4 DEFICIENCY TLR2 4 17 8.57e-01 -2.53e-02 9.57e-01
REACTOME SIGNALING BY TGFB FAMILY MEMBERS 119 8.57e-01 -9.56e-03 9.57e-01
REACTOME CELLULAR HEXOSE TRANSPORT 21 8.58e-01 -2.26e-02 9.57e-01
REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS 8 8.58e-01 -3.66e-02 9.57e-01
REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING 12 8.58e-01 -2.98e-02 9.57e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL 15 8.58e-01 -2.66e-02 9.57e-01
REACTOME HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS 9 8.60e-01 -3.39e-02 9.58e-01
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION 250 8.61e-01 -6.45e-03 9.58e-01
REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING 25 8.63e-01 1.99e-02 9.59e-01
REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA 11 8.64e-01 2.99e-02 9.59e-01
REACTOME MITOTIC TELOPHASE CYTOKINESIS 11 8.64e-01 2.99e-02 9.59e-01
REACTOME SYNTHESIS OF PI 5 8.64e-01 4.42e-02 9.59e-01
REACTOME NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 19 8.65e-01 -2.25e-02 9.60e-01
REACTOME HEMOSTASIS 591 8.65e-01 -4.08e-03 9.60e-01
REACTOME CREATION OF C4 AND C2 ACTIVATORS 14 8.68e-01 -2.57e-02 9.61e-01
REACTOME SHC RELATED EVENTS TRIGGERED BY IGF1R 9 8.68e-01 -3.19e-02 9.61e-01
REACTOME SIGNALING BY EGFR IN CANCER 25 8.70e-01 -1.89e-02 9.63e-01
REACTOME MET RECEPTOR RECYCLING 10 8.71e-01 -2.96e-02 9.63e-01
REACTOME RELEASE OF HH NP FROM THE SECRETING CELL 8 8.72e-01 3.30e-02 9.63e-01
REACTOME HDL CLEARANCE 5 8.75e-01 4.07e-02 9.65e-01
REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE 10 8.75e-01 -2.87e-02 9.65e-01
REACTOME HYALURONAN BIOSYNTHESIS AND EXPORT 5 8.75e-01 -4.05e-02 9.65e-01
REACTOME EPH EPHRIN SIGNALING 90 8.77e-01 -9.41e-03 9.65e-01
REACTOME NUCLEAR SIGNALING BY ERBB4 32 8.77e-01 -1.57e-02 9.65e-01
REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION 26 8.78e-01 1.74e-02 9.65e-01
REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS 11 8.79e-01 -2.66e-02 9.65e-01
REACTOME DEGRADATION OF CYSTEINE AND HOMOCYSTEINE 15 8.79e-01 2.27e-02 9.65e-01
REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 22 8.79e-01 -1.87e-02 9.65e-01
REACTOME COMPLEMENT CASCADE 54 8.79e-01 -1.19e-02 9.65e-01
REACTOME CONSTITUTIVE SIGNALING BY EGFRVIII 15 8.80e-01 2.25e-02 9.65e-01
REACTOME REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM 11 8.81e-01 2.61e-02 9.65e-01
REACTOME SIGNALING BY FLT3 ITD AND TKD MUTANTS 16 8.82e-01 2.15e-02 9.65e-01
REACTOME INTERLEUKIN 27 SIGNALING 11 8.85e-01 2.52e-02 9.65e-01
REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES 38 8.85e-01 1.35e-02 9.65e-01
REACTOME PHENYLALANINE AND TYROSINE METABOLISM 11 8.85e-01 2.51e-02 9.65e-01
REACTOME CYP2E1 REACTIONS 10 8.85e-01 2.63e-02 9.65e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE 11 8.86e-01 -2.50e-02 9.65e-01
REACTOME CYTOPROTECTION BY HMOX1 59 8.86e-01 1.08e-02 9.65e-01
REACTOME RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION 22 8.87e-01 1.76e-02 9.65e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL 14 8.87e-01 -2.19e-02 9.65e-01
REACTOME SIGNALING BY KIT IN DISEASE 20 8.88e-01 -1.81e-02 9.65e-01
REACTOME TRANSPORT OF FATTY ACIDS 8 8.89e-01 2.86e-02 9.65e-01
REACTOME ZINC TRANSPORTERS 15 8.89e-01 2.09e-02 9.65e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY DVL INTERACTING PROTEINS 5 8.89e-01 3.62e-02 9.65e-01
REACTOME INTERLEUKIN 1 PROCESSING 9 8.89e-01 2.69e-02 9.65e-01
REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS 11 8.89e-01 -2.43e-02 9.65e-01
REACTOME INLA MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS 9 8.91e-01 -2.64e-02 9.66e-01
REACTOME MITOCHONDRIAL CALCIUM ION TRANSPORT 23 8.92e-01 -1.64e-02 9.67e-01
REACTOME POST TRANSCRIPTIONAL SILENCING BY SMALL RNAS 7 8.92e-01 -2.95e-02 9.67e-01
REACTOME CHYLOMICRON ASSEMBLY 10 8.94e-01 -2.44e-02 9.67e-01
REACTOME REGULATION OF RUNX1 EXPRESSION AND ACTIVITY 17 8.95e-01 1.84e-02 9.68e-01
REACTOME SPRY REGULATION OF FGF SIGNALING 16 8.96e-01 1.90e-02 9.68e-01
REACTOME SYNTHESIS OF DIPHTHAMIDE EEF2 8 8.96e-01 -2.68e-02 9.68e-01
REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM 20 8.98e-01 -1.66e-02 9.69e-01
REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS 15 8.98e-01 1.91e-02 9.69e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE 74 9.00e-01 -8.47e-03 9.70e-01
REACTOME CLATHRIN MEDIATED ENDOCYTOSIS 139 9.01e-01 6.09e-03 9.71e-01
REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV 1 INFECTION 5 9.02e-01 3.17e-02 9.71e-01
REACTOME PI3K EVENTS IN ERBB2 SIGNALING 16 9.03e-01 1.76e-02 9.71e-01
REACTOME PROSTANOID LIGAND RECEPTORS 9 9.04e-01 -2.32e-02 9.72e-01
REACTOME SIGNALING BY NTRK2 TRKB 25 9.06e-01 1.37e-02 9.73e-01
REACTOME NGF INDEPENDANT TRKA ACTIVATION 5 9.10e-01 -2.93e-02 9.76e-01
REACTOME REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION 9 9.10e-01 -2.17e-02 9.76e-01
REACTOME HUR ELAVL1 BINDS AND STABILIZES MRNA 8 9.10e-01 2.30e-02 9.76e-01
REACTOME ERK MAPK TARGETS 20 9.10e-01 -1.45e-02 9.76e-01
REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING 89 9.12e-01 -6.81e-03 9.76e-01
REACTOME MEMBRANE TRAFFICKING 603 9.12e-01 2.65e-03 9.76e-01
REACTOME TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS 55 9.13e-01 8.55e-03 9.76e-01
REACTOME METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES 33 9.15e-01 -1.08e-02 9.78e-01
REACTOME HEME BIOSYNTHESIS 13 9.15e-01 -1.70e-02 9.78e-01
REACTOME METABOLISM OF INGESTED SEMET SEC MESEC INTO H2SE 7 9.16e-01 2.29e-02 9.78e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS 5 9.18e-01 -2.66e-02 9.79e-01
REACTOME RHOBTB3 ATPASE CYCLE 8 9.20e-01 2.06e-02 9.80e-01
REACTOME FATTY ACID METABOLISM 170 9.21e-01 -4.43e-03 9.80e-01
REACTOME METABOLISM OF VITAMINS AND COFACTORS 185 9.22e-01 -4.20e-03 9.80e-01
REACTOME LRR FLII INTERACTING PROTEIN 1 LRRFIP1 ACTIVATES TYPE I IFN PRODUCTION 5 9.22e-01 2.54e-02 9.80e-01
REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL 129 9.22e-01 4.98e-03 9.80e-01
REACTOME SODIUM PROTON EXCHANGERS 7 9.23e-01 -2.12e-02 9.80e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE 8 9.23e-01 -1.97e-02 9.80e-01
REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION 20 9.24e-01 -1.23e-02 9.81e-01
REACTOME RAS PROCESSING 22 9.25e-01 1.17e-02 9.81e-01
REACTOME RHO GTPASES ACTIVATE CIT 19 9.25e-01 -1.25e-02 9.81e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM 38 9.27e-01 -8.56e-03 9.82e-01
REACTOME MTORC1 MEDIATED SIGNALLING 23 9.28e-01 1.09e-02 9.82e-01
REACTOME INTERLEUKIN 2 SIGNALING 11 9.29e-01 -1.54e-02 9.83e-01
REACTOME FATTY ACYL COA BIOSYNTHESIS 36 9.30e-01 -8.44e-03 9.83e-01
REACTOME DISEASES OF BASE EXCISION REPAIR 5 9.31e-01 -2.25e-02 9.83e-01
REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX 14 9.33e-01 1.30e-02 9.84e-01
REACTOME FCERI MEDIATED MAPK ACTIVATION 32 9.33e-01 -8.59e-03 9.84e-01
REACTOME EPHRIN SIGNALING 17 9.33e-01 1.18e-02 9.84e-01
REACTOME GOLGI TO ER RETROGRADE TRANSPORT 132 9.34e-01 -4.20e-03 9.84e-01
REACTOME ACTIVATION OF PPARGC1A PGC 1ALPHA BY PHOSPHORYLATION 10 9.35e-01 -1.50e-02 9.84e-01
REACTOME LONG TERM POTENTIATION 22 9.35e-01 -1.00e-02 9.84e-01
REACTOME RHO GTPASES ACTIVATE KTN1 11 9.36e-01 1.40e-02 9.84e-01
REACTOME LYSINE CATABOLISM 12 9.37e-01 -1.32e-02 9.84e-01
REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR 11 9.37e-01 1.38e-02 9.84e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE 5 9.37e-01 -2.04e-02 9.84e-01
REACTOME SARS COV 2 MODULATES AUTOPHAGY 11 9.40e-01 1.31e-02 9.86e-01
REACTOME APEX1 INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY 7 9.40e-01 1.64e-02 9.86e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FYN 7 9.42e-01 -1.58e-02 9.87e-01
REACTOME LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS 19 9.45e-01 9.19e-03 9.88e-01
REACTOME GLYCOGEN SYNTHESIS 13 9.45e-01 -1.11e-02 9.88e-01
REACTOME RUNX2 REGULATES BONE DEVELOPMENT 29 9.46e-01 7.31e-03 9.88e-01
REACTOME HISTIDINE CATABOLISM 8 9.46e-01 1.38e-02 9.88e-01
REACTOME CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA 63 9.46e-01 4.91e-03 9.88e-01
REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS 35 9.48e-01 -6.34e-03 9.90e-01
REACTOME PRE NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM 6 9.49e-01 -1.51e-02 9.90e-01
REACTOME DISORDERS OF TRANSMEMBRANE TRANSPORTERS 170 9.50e-01 2.77e-03 9.90e-01
REACTOME PROTEIN METHYLATION 17 9.51e-01 8.64e-03 9.90e-01
REACTOME TRAIL SIGNALING 8 9.51e-01 1.26e-02 9.90e-01
REACTOME PECAM1 INTERACTIONS 12 9.51e-01 1.02e-02 9.90e-01
REACTOME VASOPRESSIN LIKE RECEPTORS 5 9.53e-01 1.51e-02 9.90e-01
REACTOME BILE ACID AND BILE SALT METABOLISM 45 9.54e-01 -4.97e-03 9.90e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES 43 9.55e-01 -5.02e-03 9.90e-01
REACTOME DEPOLYMERISATION OF THE NUCLEAR LAMINA 14 9.55e-01 8.67e-03 9.90e-01
REACTOME GAP JUNCTION TRAFFICKING AND REGULATION 49 9.55e-01 4.63e-03 9.90e-01
REACTOME RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS 5 9.56e-01 -1.44e-02 9.90e-01
REACTOME POLO LIKE KINASE MEDIATED EVENTS 16 9.56e-01 7.94e-03 9.90e-01
REACTOME NRCAM INTERACTIONS 6 9.57e-01 1.27e-02 9.90e-01
REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 122 9.58e-01 -2.78e-03 9.90e-01
REACTOME ARYL HYDROCARBON RECEPTOR SIGNALLING 6 9.58e-01 -1.23e-02 9.90e-01
REACTOME GAP JUNCTION ASSEMBLY 36 9.58e-01 5.02e-03 9.90e-01
REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF 53 9.60e-01 4.00e-03 9.91e-01
REACTOME ORGANIC ANION TRANSPORTERS 10 9.61e-01 9.00e-03 9.91e-01
REACTOME BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA 5 9.61e-01 -1.26e-02 9.91e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS 6 9.62e-01 -1.12e-02 9.92e-01
REACTOME SEMA3A PAK DEPENDENT AXON REPULSION 14 9.65e-01 -6.77e-03 9.92e-01
REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX 36 9.65e-01 -4.23e-03 9.92e-01
REACTOME NUCLEOTIDE CATABOLISM 35 9.66e-01 -4.20e-03 9.92e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION 36 9.67e-01 3.99e-03 9.92e-01
REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL 41 9.68e-01 -3.63e-03 9.92e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING 6 9.69e-01 -9.27e-03 9.92e-01
REACTOME CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS 100 9.69e-01 -2.22e-03 9.92e-01
REACTOME KINESINS 59 9.70e-01 -2.87e-03 9.92e-01
REACTOME CIRCADIAN CLOCK 68 9.70e-01 2.60e-03 9.92e-01
REACTOME SIGNALING BY ERYTHROPOIETIN 25 9.71e-01 -4.14e-03 9.92e-01
REACTOME ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY 10 9.73e-01 -6.26e-03 9.92e-01
REACTOME TRIGLYCERIDE CATABOLISM 23 9.73e-01 -4.08e-03 9.92e-01
REACTOME INTERLEUKIN 21 SIGNALING 9 9.74e-01 6.36e-03 9.92e-01
REACTOME NEGATIVE REGULATION OF MET ACTIVITY 20 9.74e-01 -4.23e-03 9.92e-01
REACTOME DNA DAMAGE REVERSAL 8 9.74e-01 6.68e-03 9.92e-01
REACTOME SCAVENGING BY CLASS A RECEPTORS 19 9.74e-01 4.28e-03 9.92e-01
REACTOME SIGNALING BY ERBB2 50 9.74e-01 -2.62e-03 9.92e-01
REACTOME ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY 10 9.75e-01 5.82e-03 9.92e-01
REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III 31 9.75e-01 -3.25e-03 9.92e-01
REACTOME SIGNALING BY PTK6 54 9.75e-01 -2.43e-03 9.92e-01
REACTOME CARNITINE METABOLISM 13 9.76e-01 4.88e-03 9.92e-01
REACTOME MATURATION OF SARS COV 2 SPIKE PROTEIN 35 9.77e-01 2.86e-03 9.92e-01
REACTOME BETA OXIDATION OF PRISTANOYL COA 9 9.77e-01 5.43e-03 9.92e-01
REACTOME SMALL INTERFERING RNA SIRNA BIOGENESIS 9 9.78e-01 5.41e-03 9.92e-01
REACTOME SIGNALING BY ERBB4 57 9.78e-01 -2.14e-03 9.92e-01
REACTOME IRS ACTIVATION 5 9.79e-01 -6.78e-03 9.92e-01
REACTOME EPH EPHRIN MEDIATED REPULSION OF CELLS 50 9.79e-01 -2.13e-03 9.92e-01
REACTOME ENOS ACTIVATION 11 9.80e-01 -4.46e-03 9.92e-01
REACTOME RHO GTPASES ACTIVATE IQGAPS 31 9.82e-01 2.38e-03 9.94e-01
REACTOME NTRK2 ACTIVATES RAC1 5 9.82e-01 -5.74e-03 9.94e-01
REACTOME EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION 27 9.85e-01 -2.03e-03 9.96e-01
REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS 14 9.86e-01 -2.77e-03 9.96e-01
REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS 45 9.89e-01 -1.24e-03 9.96e-01
REACTOME NEPHRIN FAMILY INTERACTIONS 22 9.89e-01 -1.75e-03 9.96e-01
REACTOME SIGNALING BY ERBB2 ECD MUTANTS 16 9.89e-01 -1.92e-03 9.96e-01
REACTOME GLUCAGON TYPE LIGAND RECEPTORS 32 9.90e-01 1.29e-03 9.96e-01
REACTOME CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND 16 9.90e-01 1.77e-03 9.96e-01
REACTOME CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2 11 9.90e-01 -2.07e-03 9.96e-01
REACTOME TRANSPORT OF ORGANIC ANIONS 10 9.91e-01 -2.00e-03 9.96e-01
REACTOME INITIAL TRIGGERING OF COMPLEMENT 21 9.93e-01 -1.13e-03 9.96e-01
REACTOMEMATURATION OF SARS COV 1 NUCLEOPROTEIN 11 9.93e-01 1.44e-03 9.96e-01
REACTOME CALCINEURIN ACTIVATES NFAT 9 9.93e-01 -1.59e-03 9.96e-01
REACTOME DEFECTS IN VITAMIN AND COFACTOR METABOLISM 21 9.93e-01 1.03e-03 9.96e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL 24 9.93e-01 9.63e-04 9.96e-01
REACTOME NEUREXINS AND NEUROLIGINS 51 9.94e-01 6.04e-04 9.96e-01
REACTOME NOD1 2 SIGNALING PATHWAY 33 9.94e-01 -7.12e-04 9.96e-01
REACTOME RETROGRADE NEUROTROPHIN SIGNALLING 14 9.99e-01 -2.73e-04 9.99e-01
REACTOME SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX 15 9.99e-01 -2.55e-04 9.99e-01
REACTOME CD209 DC SIGN SIGNALING 20 1.00e+00 9.10e-06 1.00e+00



Detailed Gene set reports



REACTOME_METABOLISM_OF_RNA

REACTOME_METABOLISM_OF_RNA
1313
set REACTOME_METABOLISM_OF_RNA
setSize 675
pANOVA 1.72e-17
s.dist 0.192
p.adjustANOVA 2.83e-14



Top enriched genes

Top 20 genes
GeneID Gene Rank
ZNF473 10484
RPS5 10401
SMG1 10380
ZFP36L1 10330
UTP20 10207
SET 10185
ZMAT2 10172
POP7 10162
APOBEC3C 10139
PHF5A 10133
RPL39L 10015
TYW1 10011
RPS13 10010
TSEN15 10004
ZFP36 9905
CWC15 9904
PSMB8 9883
SKIC8 9840
TRMT61B 9838
SNRPD2 9776

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ZNF473 10484.0
RPS5 10401.0
SMG1 10380.0
ZFP36L1 10330.0
UTP20 10207.0
SET 10185.0
ZMAT2 10172.0
POP7 10162.0
APOBEC3C 10139.0
PHF5A 10133.0
RPL39L 10015.0
TYW1 10011.0
RPS13 10010.0
TSEN15 10004.0
ZFP36 9905.0
CWC15 9904.0
PSMB8 9883.0
SKIC8 9840.0
TRMT61B 9838.0
SNRPD2 9776.0
RPLP0 9720.0
IMP3 9701.0
SNU13 9681.0
SNRPA 9631.0
TRNT1 9579.0
APOBEC3B 9547.0
GEMIN7 9544.0
RRP36 9543.0
APOBEC4 9513.0
GTF2H3 9509.0
EXOSC5 9460.0
GEMIN2 9444.0
PSMC1 9440.0
RPL27 9406.0
GLE1 9377.0
SNRPF 9329.0
WDR3 9298.0
RPL6 9269.0
POLR2K 9241.0
NIP7 9175.0
RBM8A 9140.0
XPOT 9108.0
ISY1 9061.0
RBM39 9022.0
LUC7L3 9021.0
RPL27A 8979.0
RPS28 8978.0
PRPF4 8965.0
POLR2C 8943.0
SNRPD3 8937.0
RPS8 8920.0
HSPA8 8896.0
SARNP 8886.0
NXT1 8885.0
TXNL4A 8857.0
RPS12 8794.0
EXOSC8 8764.0
HNRNPA1 8761.0
PPIL3 8750.0
CRNKL1 8699.0
SNW1 8694.0
CTU2 8659.0
SF3B5 8644.0
RPS25 8638.0
PSMD4 8637.0
FUS 8636.0
POP5 8604.0
RPL19 8597.0
RPL9 8592.0
NOP2 8577.0
HNRNPC 8571.0
LENG1 8570.0
PSME2 8563.0
RPL12 8542.0
YBX1 8540.0
CPSF2 8530.0
LSM7 8523.0
MRM1 8522.0
PRKRIP1 8517.0
RPS6 8501.0
APOBEC1 8487.0
SRSF1 8484.0
SMN1 8480.5
SMN2 8480.5
PSMD7 8416.0
SRSF8 8381.0
GTPBP3 8349.0
TRMT10A 8300.0
UTP4 8287.0
PSMB3 8251.0
PCF11 8247.0
RPL41 8240.0
RPL18 8234.0
WBP11 8200.0
POLR2D 8181.0
EXOSC9 8176.0
RPL10A 8175.0
SF3B4 8174.0
NOL12 8142.0
RPS2 8109.0
NUP153 8090.0
FAU 8086.0
RPL5 8055.0
USP39 8048.0
RPL36AL 8033.5
RIOK2 8010.0
HNRNPL 7999.0
RPS3A 7941.0
POP1 7935.0
NUP58 7912.0
RPL23 7907.0
PSMC6 7899.0
THOC7 7879.0
RPS18 7868.0
CDC40 7861.0
FAM32A 7860.0
FTSJ3 7856.0
TSEN34 7843.0
C2orf49 7835.0
MPHOSPH10 7825.0
PPWD1 7797.0
PTBP1 7790.0
PCBP1 7777.0
RPL13 7712.0
GAR1 7709.0
RPS27A 7698.0
XPO1 7679.0
DDX46 7661.0
C9orf78 7600.0
EIF4A1 7576.0
RNMT 7539.0
RPL13A 7489.5
LSM4 7420.0
SRSF3 7367.0
ZCRB1 7361.0
PDCD7 7359.0
RPLP2 7348.0
UBB 7319.0
DHX9 7301.0
DDX20 7263.0
RRP9 7252.0
RPL3 7194.0
RPPH1 7186.0
SNRNP25 7151.0
RPL4 7148.0
PSMC3 7021.0
PPP2R1A 6985.0
RPS26 6957.0
UBL5 6954.0
SF3A3 6945.0
IGF2BP2 6941.0
OSGEP 6918.0
DDX39A 6916.0
RPL38 6914.0
RPS21 6901.0
RPL35A 6893.0
TGS1 6886.0
TRMT5 6885.0
PSMB9 6881.0
RAN 6824.0
RPL21 6804.0
PSMA2 6802.0
EMG1 6787.0
THOC5 6782.0
BUD31 6756.0
TRMT11 6753.0
YWHAB 6683.0
MTO1 6655.0
PRPF19 6637.0
WDR75 6615.0
LSM1 6607.0
WTAP 6566.0
SRSF6 6524.0
TRMT1 6443.0
RPL28 6441.0
GTF2F1 6376.0
RBM22 6365.0
QTRT2 6342.0
EFTUD2 6296.0
NUP214 6207.0
NUP88 6185.0
ZNF830 6157.0
CNOT9 6134.0
RPL34 6124.0
HNRNPU 6103.0
CNOT6 6096.0
RPL7 6080.0
LSM8 6079.0
POLR2I 6073.0
NUP160 6067.0
RPL17 6034.0
ADAT2 6019.0
TRMT10C 5994.0
ALYREF 5973.0
DHX35 5958.0
YWHAZ 5941.0
ZC3H11A 5928.0
PSMD12 5909.0
SNRPG 5906.0
SNUPN 5892.0
RPS29 5882.0
LSM5 5866.0
GCFC2 5816.0
PSMA3 5797.0
PHAX 5778.0
METTL3 5773.0
CPSF6 5763.0
WDR36 5744.0
PSMC2 5730.0
CWC25 5724.0
PSMA1 5699.0
RPS15 5697.0
THOC6 5656.0
HNRNPK 5648.0
RANBP2 5556.0
SF3A2 5551.0
WBP4 5549.0
PATL1 5528.0
NUP62 5513.0
PSMB4 5511.0
NUP35 5491.0
RPL18A 5467.0
PSMA7 5457.0
CSTF1 5452.0
PNRC2 5441.0
TRMT112 5435.0
DDX21 5401.0
NUP107 5390.0
RPL32 5357.0
BCAS2 5290.0
WDR46 5281.0
PSMC5 5252.0
SEH1L 5251.0
RPS15A 5210.0
FYTTD1 5205.0
RIOK3 5187.0
HNRNPA2B1 5128.0
DCPS 5115.0
DDX23 5098.0
IK 5064.0
RPS10 5051.0
RPS19 5043.0
NOP56 5023.0
CNOT10 5011.0
SMG9 5001.0
PSMA4 4968.0
POLR2H 4937.0
SMG6 4923.0
METTL14 4902.0
CCAR1 4859.0
HNRNPD 4808.0
CLP1 4800.0
SRSF11 4767.0
RPL35 4765.0
NAT10 4763.0
RPS20 4727.0
IMP4 4723.0
POP4 4699.0
NCBP2 4667.0
MAPK14 4661.0
RBM28 4652.0
SLBP 4643.0
LSM2 4624.0
GSPT1 4602.0
EIF4A2 4483.0
PRPF38A 4451.0
TRMT6 4380.0
BYSL 4372.0
UTP15 4351.0
LSM11 4319.0
PAIP1 4305.0
CWC27 4299.0
CTU1 4292.0
FBL 4272.0
SRSF2 4267.0
NOB1 4264.0
RIOK1 4250.0
PUS7 4244.0
SRSF7 4237.0
PAN2 4232.0
PRMT5 4230.0
CNOT11 4226.0
EIF4B 4211.0
CNOT8 4200.0
NUP37 4196.0
PSMD3 4188.0
SNRPE 4155.0
RPP25 4147.0
TSR3 4091.0
NOP58 4068.0
IGF2BP1 4043.0
DDX6 4029.0
ISG20L2 4028.0
FAM98B 3941.0
ADAT1 3852.0
HSPA1A 3836.0
DUS2 3807.0
TRDMT1 3792.0
SMU1 3766.0
LTV1 3697.0
PCBP2 3688.0
SMNDC1 3686.0
RPSA 3658.0
UPF3A 3657.0
NUP54 3624.0
TNPO1 3598.0
SYF2 3587.0
PNN 3569.0
EIF4E 3532.0
HNRNPR 3489.0
SF3B6 3468.0
NUP85 3458.0
UPF2 3441.0
THOC1 3438.0
SNRNP48 3372.0
PSMC4 3370.0
POLR2B 3342.0
NUP50 3335.0
PAPOLA 3288.0
U2AF1L4 3251.0
PSMD1 3237.0
WDR4 3219.0
RPL26L1 3215.0
PPIL1 3187.0
RTRAF 3140.0
RPL8 3119.0
MPHOSPH6 3084.0
PNO1 3075.0
RBM7 3042.0
DIMT1 2980.0
NUP133 2881.0
DDX41 2879.0
KHSRP 2866.0
GEMIN6 2822.0
POLR2G 2774.0
PSMD5 2770.0
CNOT2 2760.0
RPS24 2748.0
RPP30 2706.0
TSEN2 2671.0
RPL30 2631.0
CDK7 2530.0
RPL37 2527.0
SF3B3 2523.0
HNRNPA3 2501.0
ERI1 2477.0
RPS16 2475.0
TSEN54 2467.0
MAGOHB 2447.0
PAN3 2418.0
DDX39B 2385.0
RPL11 2329.0
RPS27L 2308.0
CSTF2T 2301.0
TRIT1 2244.0
GTF2F2 2212.0
U2SURP 2211.0
AAAS 2175.0
PSMB10 2137.0
SRSF10 2060.0
RPS23 2004.0
ZBTB8OS 2003.0
RPP40 1990.0
SDE2 1962.0
DCAF13 1958.0
DDX52 1952.0
SMG5 1946.0
CNOT7 1938.0
DDX42 1916.0
NHP2 1913.0
POLR2E 1875.0
KRR1 1863.0
DHX8 1752.0
TRA2B 1749.0
PABPN1 1738.0
HSPB1 1700.0
PSMB1 1698.0
A1CF 1679.0
LSM6 1612.0
SNRPN 1552.0
SF1 1544.0
CCDC12 1534.0
SAP18 1491.0
SRSF5 1443.0
RPL36 1365.0
MAGOH 1349.0
NXF1 1289.0
RPS11 1269.0
PSMA8 1258.0
SNIP1 1257.0
PSMD2 1209.0
PPIH 1205.0
RPP21 1142.0
RPS27 1132.0
BUD13 1064.0
PSMD9 1039.0
SRRM1 1034.0
NUDT21 1004.0
UPF1 997.0
APOBEC2 996.0
PRPF31 995.0
PRPF40A 918.0
BUD23 881.0
HNRNPM 859.0
CCNH 840.0
CHTOP 815.0
ERCC2 808.0
PSMD14 794.0
RPLP1 792.0
DCP1B 789.0
SF3B1 782.0
CSTF3 775.0
SMG8 757.0
UTP14C 750.0
SMG7 692.0
MRM2 624.0
ETF1 594.0
CPSF4 582.0
PDCD11 539.0
HNRNPH1 534.0
ZMAT5 484.0
HBS1L 460.0
RBM25 456.0
RPL22 440.0
PSMD11 411.0
PSMA5 410.0
RBM17 362.0
RPS14 322.0
GTF2H5 189.0
UTP25 138.0
PRORP 78.0
RPL24 57.0
NDC1 28.0
C1D 4.0
NUP155 -40.0
WDR77 -51.0
HEATR1 -55.0
RPL14 -57.0
SNRNP35 -88.0
PPP2CA -89.0
DCP1A -92.0
SLU7 -122.0
PSMB5 -134.0
SRRT -154.0
GEMIN4 -197.0
DHX16 -264.0
NOL11 -276.0
SKIC3 -280.0
HNRNPF -288.0
MTERF4 -324.0
DDX5 -377.0
CPSF3 -389.0
ALKBH8 -496.0
NOP14 -498.0
LCMT2 -514.0
CNOT4 -572.0
GNL3 -573.0
UTP18 -623.0
UBC -640.0
SNRPA1 -644.0
SNRPD1 -647.0
PES1 -692.0
EXOSC1 -737.0
WDR12 -837.0
RPS3 -850.0
PLRG1 -915.0
CPSF7 -931.0
PRPF18 -978.0
EIF4A3 -993.0
SF3B2 -995.0
PPP2R2A -1010.0
TEX10 -1032.0
QTRT1 -1081.0
EXOSC2 -1111.0
PELP1 -1125.0
PSMD13 -1223.0
CACTIN -1253.0
RPL23A -1287.0
TPR -1291.0
NUP98 -1370.0
DIS3 -1418.0
NSUN4 -1451.0
NUP42 -1491.0
CDC5L -1498.0
EBNA1BP2 -1500.0
SUPT5H -1539.0
UTP6 -1552.0
RPL15 -1589.0
CDKAL1 -1603.0
LSM3 -1616.0
TNKS1BP1 -1637.0
GTF2H1 -1760.0
UTP11 -1777.0
NUP93 -1778.0
POLDIP3 -1826.0
RPS9 -1972.0
NCL -2159.0
NSUN2 -2223.0
WDR70 -2238.0
PSME3 -2265.0
MFAP1 -2278.0
SYMPK -2295.0
SNRNP40 -2363.0
PRKCD -2402.0
ACIN1 -2405.0
SNRPB2 -2424.0
RNPC3 -2497.0
EXOSC6 -2529.0
RBM5 -2548.0
EPRS1 -2577.0
NUP188 -2578.0
EIF4G1 -2605.0
EXOSC7 -2703.0
METTL1 -2704.0
EXOSC3 -2706.0
TFIP11 -2728.0
DNAJC8 -2749.0
AQR -2768.0
UBA52 -2875.0
TYW5 -2901.0
CLNS1A -2927.0
TRMT12 -2964.0
DDX47 -2975.0
PSMB7 -2995.0
NOP10 -3018.0
MAPKAPK2 -3023.0
PSME4 -3042.0
EXOSC4 -3047.0
MRM3 -3177.0
NCBP1 -3261.0
THUMPD1 -3342.0
PRKCA -3379.0
MAPK11 -3435.0
RTCB -3439.0
MNAT1 -3468.0
NUP205 -3512.0
SNRPC -3551.0
RPS7 -3608.0
DHX15 -3617.0
LSM10 -3629.0
FIP1L1 -3812.0
ADAT3 -3826.0
SNRPB -3828.0
DHX38 -3833.0
POLR2F -3844.0
PSMA6 -3897.0
PRPF8 -3970.0
GTF2H4 -4059.0
SENP3 -4078.0
TSR1 -4184.0
RPP38 -4188.0
GEMIN5 -4203.0
PSMB2 -4270.0
TPRKB -4304.0
POLR2L -4399.0
WDR33 -4495.0
THG1L -4505.0
RPL3L -4519.0
XRN1 -4532.0
CWF19L2 -4566.0
NUP210 -4632.0
DCP2 -4756.0
RPL29 -4767.0
SEM1 -4777.0
FCF1 -4784.0
NOL6 -4793.0
SEC13 -4820.0
CNOT6L -4821.0
NT5C3B -4967.0
PSMD8 -5041.0
TRMU -5075.0
RRP1 -5125.0
PRCC -5135.0
RBM42 -5162.0
IGF2BP3 -5224.0
SRSF9 -5277.0
ANP32A -5314.0
TUT7 -5388.0
PSMF1 -5472.0
SNRNP27 -5486.0
TNFSF13 -5539.0
XRN2 -5623.0
ADAR -5648.0
BMS1 -5656.0
RPL37A -5673.0
PUS3 -5690.0
PPIG -5700.0
PARN -5744.0
MTREX -5758.0
RPL7A -5783.0
NOL9 -5822.0
PSMD6 -5971.0
PABPC1 -5994.0
TRMT13 -6000.0
NUP43 -6011.0
RNGTT -6046.0
CPSF1 -6053.0
SF3A1 -6066.0
TP53RK -6208.0
CNOT3 -6228.0
TYW3 -6242.0
RPL22L1 -6323.0
EXOSC10 -6330.0
TCERG1 -6336.0
TBL3 -6393.0
XAB2 -6417.0
UTP3 -6469.0
PWP2 -6487.0
TUT4 -6536.0
NSUN6 -6587.0
ELAVL1 -6613.0
POM121 -6621.0
AKT1 -6634.0
TRMT44 -6712.0
RNPS1 -6758.0
CNOT1 -6783.0
PRPF6 -6865.0
PSMB6 -6874.0
RPL26 -6909.0
CWC22 -6935.0
SRSF12 -6979.0
BOP1 -7016.0
EDC4 -7042.0
SKIC2 -7060.0
DHX37 -7089.0
CASC3 -7100.0
PPIL4 -7129.0
SRRM2 -7130.0
SNRNP200 -7137.0
PUF60 -7159.0
RAE1 -7253.0
SRSF4 -7270.0
POLR2J -7312.0
THADA -7357.0
APOBEC3A -7428.0
WDR18 -7446.0
NSRP1 -7471.0
ADARB1 -7493.0
POLR2A -7563.0
POM121C -7658.0
RPP14 -7729.0
PPP1R8 -7777.0
DDX1 -7960.0
WDR43 -8007.0
CSNK1D -8034.0
EDC3 -8112.0
PUS1 -8117.0
PPIE -8126.0
PSME1 -8232.0
U2AF2 -8312.0
DDX49 -8373.0
TFB1M -8412.0
TRMT9B -8600.0
ELAC2 -8627.0
SNRNP70 -8629.0
RPL31 -8668.0
NOC4L -8734.0
SUGP1 -8744.0
YJU2 -8859.0
CTNNBL1 -9023.0
RCL1 -9030.0
TRMT61A -9041.0
URM1 -9129.0
PSMB11 -9151.0
PRPF3 -9233.0
CHERP -9359.0
PPIL2 -9370.0
APOBEC3H -9374.0
ERCC3 -9580.0
GPATCH1 -9589.0
THOC3 -9696.0
CSNK1E -9776.0
SART1 -9806.0
RPL10L -10702.0
RRP7A -10955.0



REACTOME_TRANSLATION

REACTOME_TRANSLATION
1152
set REACTOME_TRANSLATION
setSize 278
pANOVA 2.28e-15
s.dist 0.276
p.adjustANOVA 1.87e-12



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS5 10401
MRPS16 10267
NARS1 10221
MRPS15 10106
RPL39L 10015
RPS13 10010
MRPS18C 9864
MRPL40 9831
EIF2B1 9802
SRP54 9793
RPLP0 9720
SEC61B 9705
MRPL57 9674
MRPL45 9575
MRPL27 9482
MRPL51 9470
EIF2S2 9447
CHCHD1 9428
RPL27 9406
RPL6 9269

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS5 10401.0
MRPS16 10267.0
NARS1 10221.0
MRPS15 10106.0
RPL39L 10015.0
RPS13 10010.0
MRPS18C 9864.0
MRPL40 9831.0
EIF2B1 9802.0
SRP54 9793.0
RPLP0 9720.0
SEC61B 9705.0
MRPL57 9674.0
MRPL45 9575.0
MRPL27 9482.0
MRPL51 9470.0
EIF2S2 9447.0
CHCHD1 9428.0
RPL27 9406.0
RPL6 9269.0
MRPL33 8988.0
RPL27A 8979.0
RPS28 8978.0
MRPL50 8956.0
ERAL1 8946.0
RPS8 8920.0
EIF3J 8894.0
RPS12 8794.0
TRAM1 8753.0
MRPS34 8726.0
RPS25 8638.0
RPL19 8597.0
RPL9 8592.0
MRPS31 8545.0
RPL12 8542.0
MRPL10 8526.0
RPS6 8501.0
MRPS11 8467.0
TARS2 8401.0
EIF2B5 8376.0
EIF2B2 8327.0
MRPS18A 8321.0
EIF3E 8280.0
MRPL52 8254.0
RPL41 8240.0
RPL18 8234.0
RPL10A 8175.0
MRPL15 8129.0
RPS2 8109.0
FAU 8086.0
RPL5 8055.0
RPL36AL 8033.5
MRPL30 8025.0
RPS3A 7941.0
RPL23 7907.0
RPS18 7868.0
MRPL18 7849.0
MRPL21 7755.0
RPL13 7712.0
RPS27A 7698.0
RPN2 7689.0
EIF4A1 7576.0
EIF5 7520.0
RPL13A 7489.5
MRPL37 7455.0
HARS2 7402.0
MRPL9 7355.0
RPLP2 7348.0
MRPL19 7317.0
RPL3 7194.0
RPL4 7148.0
MRPL16 7117.0
EEF1G 7050.0
MRPS26 6980.0
RPS26 6957.0
MRPL12 6935.0
MRPL32 6927.0
RPL38 6914.0
RPS21 6901.0
RPL35A 6893.0
MRPL20 6879.0
EARS2 6850.0
RPL21 6804.0
EIF2S1 6710.0
MRPL49 6703.0
MARS2 6569.0
PPA1 6557.0
LARS1 6527.0
AARS1 6474.0
MRPS10 6450.0
RPL28 6441.0
MRPL35 6416.0
MRPL48 6415.0
VARS1 6358.0
MRPS17 6357.0
SRP14 6335.0
RPL34 6124.0
RPL7 6080.0
RPL17 6034.0
YARS2 6018.0
RPS29 5882.0
MRPL54 5881.0
RPS15 5697.0
MRPL46 5570.0
MRPS30 5496.0
RPL18A 5467.0
PPA2 5447.0
TRMT112 5435.0
RPL32 5357.0
MRPL55 5291.0
MRPL44 5222.0
RPS15A 5210.0
MRPL36 5209.0
DARS2 5193.0
MTIF3 5144.0
MRPS12 5101.0
RPS10 5051.0
RPS19 5043.0
MRPL17 5006.0
MTFMT 4980.0
MRPL2 4788.0
RPL35 4765.0
RPS20 4727.0
MRPL53 4711.0
GSPT1 4602.0
EIF4A2 4483.0
MRPL28 4456.0
WARS2 4358.0
DAP3 4302.0
EIF4B 4211.0
FARSB 4201.0
SEC61G 4095.0
SPCS1 4026.0
PTCD3 3897.0
EEF1A1 3873.0
MRPL11 3868.0
MTRF1L 3823.0
RPSA 3658.0
EIF3F 3644.0
N6AMT1 3563.0
EIF4E 3532.0
SARS2 3439.0
IARS1 3426.0
EIF3L 3274.0
SRP19 3248.0
RPL26L1 3215.0
RPL8 3119.0
HARS1 3068.0
GADD45GIP1 3027.0
MRPS25 2898.0
EIF3I 2811.0
KARS1 2797.0
PARS2 2773.0
SEC11A 2763.0
RPS24 2748.0
TARS1 2678.0
RPL30 2631.0
EIF3K 2561.0
RPL37 2527.0
MRPL14 2494.0
EIF3A 2478.0
RPS16 2475.0
SEC11C 2368.0
MRPS33 2362.0
RPL11 2329.0
RPS27L 2308.0
SRP72 2092.0
MRPL4 2084.0
RPS23 2004.0
SSR3 1859.0
MTIF2 1648.0
TUFM 1634.0
EEF1E1 1616.0
AURKAIP1 1591.0
EIF2B4 1579.0
RARS1 1516.0
MRPS7 1442.0
RPL36 1365.0
SSR2 1333.0
MRPL34 1274.0
RPS11 1269.0
EIF5B 1241.0
RPS27 1132.0
YARS1 964.0
MRRF 842.0
RPLP1 792.0
ETF1 594.0
EEF1A2 537.0
RPL22 440.0
RPS14 322.0
MRPL24 298.0
MRPL58 257.0
MRPS2 88.0
RPL24 57.0
MRPS21 2.0
RPL14 -57.0
EIF3G -63.0
MRPS23 -144.0
EIF2B3 -195.0
EIF3M -282.0
EIF4EBP1 -387.0
TSFM -410.0
MRPS18B -501.0
GFM2 -526.0
WARS1 -546.0
MRPS27 -566.0
RPN1 -715.0
MRPL3 -733.0
MRPL13 -785.0
EEF2 -830.0
RPS3 -850.0
SRPRA -926.0
MRPL23 -968.0
SPCS3 -1120.0
SPCS2 -1190.0
MRPS6 -1267.0
RPL23A -1287.0
FARSA -1441.0
LARS2 -1547.0
RPL15 -1589.0
MRPS24 -1734.0
MRPS28 -1788.0
RPS9 -1972.0
RARS2 -1979.0
SRPRB -2045.0
OXA1L -2311.0
SRP68 -2347.0
EPRS1 -2577.0
EIF4G1 -2605.0
GARS1 -2607.0
MRPL38 -2784.0
EIF3D -2839.0
EEF1B2 -2867.0
UBA52 -2875.0
SRP9 -3037.0
MRPS9 -3140.0
GFM1 -3152.0
MRPS14 -3285.0
MRPS35 -3288.0
AIMP1 -3384.0
RPS7 -3608.0
EIF3H -3811.0
NARS2 -3891.0
DARS1 -3941.0
MRPL41 -4066.0
MRPL1 -4197.0
VARS2 -4338.0
RPL3L -4519.0
RPL29 -4767.0
EEF1D -4848.0
EIF3B -4859.0
EIF4H -5301.0
SEC61A2 -5510.0
MRPL43 -5642.0
MRPS22 -5652.0
RPL37A -5673.0
RPL7A -5783.0
PABPC1 -5994.0
CARS2 -6123.0
MARS1 -6171.0
FARS2 -6183.0
MRPL39 -6253.0
RPL22L1 -6323.0
IARS2 -6551.0
MRPL42 -6569.0
MRPS5 -6791.0
RPL26 -6909.0
MRPL22 -6978.0
SEC61A1 -7180.0
SSR1 -7224.0
MRPL47 -7519.0
APEH -7922.0
AIMP2 -8214.0
RPL31 -8668.0
DDOST -8965.0
AARS2 -9045.0
CARS1 -9692.0
RPL10L -10702.0



REACTOME_CELL_CYCLE

REACTOME_CELL_CYCLE
190
set REACTOME_CELL_CYCLE
setSize 666
pANOVA 3.7e-11
s.dist 0.15
p.adjustANOVA 2.02e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C12 10715
MZT2B 10707
TUBB8 10699
H2BC14 10635
H2AC14 10619
TUBB4B 10590
MZT2A 10501
H2BC6 10447
H2BC17 10375
TEX15 10319
DYNLL2 10298
H4C1 10268
H2AC4 10244
SET 10185
H3C1 10183
REC8 10135
H3C6 9987
MAPRE1 9923
KIF2A 9896
PSMB8 9883

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C12 10715.0
MZT2B 10707.0
TUBB8 10699.0
H2BC14 10635.0
H2AC14 10619.0
TUBB4B 10590.0
MZT2A 10501.0
H2BC6 10447.0
H2BC17 10375.0
TEX15 10319.0
DYNLL2 10298.0
H4C1 10268.0
H2AC4 10244.0
SET 10185.0
H3C1 10183.0
REC8 10135.0
H3C6 9987.0
MAPRE1 9923.0
KIF2A 9896.0
PSMB8 9883.0
KNL1 9842.0
HAUS8 9829.0
OIP5 9823.0
TUBG2 9780.0
CTC1 9721.0
UBE2S 9716.0
HAUS1 9712.0
YWHAH 9707.0
CDK11A 9610.0
H3C2 9609.0
HSPA2 9602.0
TINF2 9588.0
CDC25B 9568.0
CDK4 9521.0
PSMC1 9440.0
MAD2L1 9381.0
CSNK2A1 9373.0
RAD1 9369.0
POLR2K 9241.0
H3C8 9237.0
H2AJ 9219.0
CDC26 9208.0
MIS18A 9109.0
SMARCA5 9103.0
MDM2 9066.0
NDEL1 8967.0
CDKN2B 8957.0
POLR2C 8943.0
H4C3 8934.0
CEP70 8931.0
RBX1 8801.0
TUBB 8793.0
RBL2 8791.0
H4C8 8774.0
H2AC20 8751.0
POLE3 8715.0
WRAP53 8712.0
ZWINT 8650.0
PSMD4 8637.0
NEK6 8585.0
TEX12 8581.0
CTDNEP1 8574.0
TUBA4B 8566.0
PSME2 8563.0
CKS1B 8493.0
CENPM 8454.0
PSMD7 8416.0
SKP1 8408.0
TUBB2B 8395.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0
RAD17 8341.0
NEDD1 8330.0
POLD4 8324.0
TP53 8272.0
TUBA4A 8265.0
PSMB3 8251.0
DMC1 8244.0
TUBG1 8218.0
KIF23 8212.0
POLR2D 8181.0
SIRT2 8159.0
PCNA 8157.0
PRIM1 8152.0
MCM5 8147.0
ORC6 8118.0
MIS18BP1 8097.0
NUP153 8090.0
NSL1 8084.0
LIN37 8022.0
H2BC9 7978.5
H3C7 7978.5
SPC24 7943.0
EML4 7914.0
NUP58 7912.0
PSMC6 7899.0
DHFR 7884.0
RB1 7836.0
H2BC21 7828.0
TYMS 7778.0
ANAPC11 7732.0
TP53BP1 7725.0
BLZF1 7723.0
GAR1 7709.0
RPS27A 7698.0
XPO1 7679.0
ZNF385A 7669.0
MYC 7649.0
AJUBA 7627.0
SUN2 7605.0
CENPE 7598.0
NBN 7592.0
H2AC18 7550.5
H2AC19 7550.5
CHEK1 7547.0
CDC25C 7483.0
GTSE1 7452.0
PLK1 7394.0
CDK1 7383.0
RAB1A 7357.0
E2F5 7351.0
RAD51C 7333.0
RBL1 7321.0
UBB 7319.0
H3C4 7298.0
CENPA 7291.0
HAUS2 7249.0
TUBA1B 7189.0
E2F1 7180.0
PAFAH1B1 7087.0
ORC4 7082.0
MSH4 7028.0
PSMC3 7021.0
SKP2 7007.0
TUBB4A 7002.0
PPP2R1A 6985.0
CEP135 6981.0
ACTR1A 6970.0
PSMB9 6881.0
MASTL 6854.0
NUMA1 6844.0
H2BC3 6830.0
RAN 6824.0
ABRAXAS1 6811.0
PSMA2 6802.0
MDC1 6793.0
HDAC1 6791.0
TPX2 6742.0
CHMP2B 6689.0
YWHAB 6683.0
PDS5A 6676.0
CDC16 6674.0
MCM3 6656.0
H2BC5 6618.0
MDM4 6604.0
CDKN2D 6595.0
LPIN2 6562.0
TERF2IP 6545.0
CEP57 6518.0
H2AZ2 6467.0
NDC80 6455.0
AURKB 6374.0
HAUS4 6371.0
FKBP6 6339.0
ANAPC16 6333.0
PCM1 6298.0
PIF1 6290.0
NUP214 6207.0
NUP88 6185.0
GINS4 6164.0
POLR2I 6073.0
NUP160 6067.0
H2BC10 6026.0
KPNB1 5988.0
AURKA 5943.0
YWHAZ 5941.0
SPC25 5934.0
PSMD12 5909.0
DNA2 5890.0
CHMP7 5849.0
ALMS1 5848.0
FEN1 5830.0
PSMA3 5797.0
PSMC2 5730.0
MIS12 5708.0
PSMA1 5699.0
SKA1 5694.0
RAB1B 5659.0
HMMR 5605.0
PMF1 5583.0
FBXO5 5571.0
RANBP2 5556.0
NUP62 5513.0
PSMB4 5511.0
NUP35 5491.0
CENPK 5486.0
CCND1 5472.0
PSMA7 5457.0
EXO1 5408.0
POLA2 5403.0
NUP107 5390.0
PRKACA 5275.0
PSMC5 5252.0
SEH1L 5251.0
RUVBL2 5250.0
CNEP1R1 5217.0
H3C11 5197.0
PPP2R5A 5135.0
CDC20 5122.0
ATR 5120.0
STAG3 5097.0
PHLDA1 5067.0
CHEK2 5061.0
POLE2 5028.0
CHTF8 5018.0
HSP90AA1 4971.0
PSMA4 4968.0
CEP152 4952.0
GINS2 4947.0
POLR2H 4937.0
KIF18A 4930.0
ENSA 4929.0
RAD9B 4864.0
GINS1 4852.0
MLH3 4821.0
PPP6C 4805.0
VRK2 4791.0
RFC5 4755.0
NEK2 4725.0
HSP90AB1 4714.0
CHMP3 4700.0
ATM 4677.0
LPIN3 4666.0
RAD51 4665.0
AKAP9 4591.0
NCAPD2 4587.0
BUB1B 4566.0
ORC2 4544.0
E2F2 4524.0
PTK6 4508.0
H2BC15 4475.0
WRN 4437.0
SKA2 4335.0
ORC1 4331.0
PPP2R5B 4283.0
TOP2A 4243.0
NUP37 4196.0
PSMD3 4188.0
CSNK2A2 4101.0
ARPP19 4058.0
DYNC1LI2 4052.0
WEE1 4032.0
CEP43 3999.0
RFC4 3986.0
RAD50 3962.0
FKBPL 3939.0
SGO1 3934.0
CDC23 3912.0
BARD1 3901.0
TERF1 3891.0
COP1 3872.0
CDC6 3859.0
CENPL 3837.0
ANAPC10 3818.0
TUBB6 3809.0
YWHAG 3771.0
CEP250 3700.0
NUP54 3624.0
MCM2 3608.0
TNPO1 3598.0
CDK2 3557.0
SYCP1 3536.0
NPM1 3477.0
NUP85 3458.0
PSMC4 3370.0
RPA3 3368.0
USO1 3354.0
POLR2B 3342.0
NUP50 3335.0
RTEL1 3315.0
TAOK1 3289.0
RAB2A 3281.0
PTTG1 3278.0
DSN1 3269.0
RHNO1 3243.0
PSMD1 3237.0
GORASP2 3216.0
H2BC8 3188.0
KIF20A 3180.0
CLSPN 3142.0
NUF2 3136.0
CENPT 3121.0
CDCA8 3106.0
CENPC 3064.0
H2AC8 3039.0
CCND3 3034.0
PPP2R5E 3022.0
MCM6 2968.0
CDKN2A 2953.0
RAB8A 2943.0
MZT1 2913.0
E2F3 2886.0
NUP133 2881.0
ANAPC4 2868.0
PPP2R5D 2818.0
BORA 2809.0
POLR2G 2774.0
PSMD5 2770.0
FOXM1 2757.0
E2F4 2753.0
B9D2 2744.0
ANAPC1 2721.0
HUS1 2686.0
CENPS 2624.0
CDKN1C 2618.0
TUBA1A 2579.0
CDK7 2530.0
CSNK2B 2449.0
H4C16 2382.0
SPDL1 2374.0
STN1 2331.0
H3C3 2303.0
HAUS5 2273.0
GSK3B 2248.0
PRDM9 2240.0
BRCA1 2223.0
AAAS 2175.0
KNTC1 2148.0
PSMB10 2137.0
BABAM1 2098.0
CCNB2 2044.0
ESCO1 2007.0
NHP2 1913.0
POLR2E 1875.0
PDS5B 1874.0
FBXL18 1781.0
DBF4 1773.0
RMI1 1759.0
RNF168 1715.0
PSMB1 1698.0
DAXX 1689.0
TOP3A 1628.0
DYNLL1 1562.0
SPO11 1530.0
RPA2 1446.0
CHMP4B 1329.0
MRE11 1313.0
H4C2 1279.0
CDC14A 1278.0
PSMA8 1258.0
CEP63 1246.0
PPP2CB 1242.0
PSMD2 1209.0
CCND2 1203.0
ANKLE2 1152.0
YWHAE 1143.0
RPS27 1132.0
LEMD3 1122.0
H4C11 1080.0
PSMD9 1039.0
PRIM2 961.0
MCM4 954.0
CENPH 938.0
MYBL2 856.0
CEP41 851.0
CEP192 843.0
CCNH 840.0
H2BC13 823.0
PSMD14 794.0
TUBGCP3 773.0
NEK9 771.0
MCM8 737.0
CHMP4A 698.0
CCNE2 668.0
RCC1 663.0
ZW10 644.0
KAT5 642.0
UIMC1 630.0
UBE2N 540.0
PLK4 535.0
DSCC1 524.0
CENPO 442.0
CLASP2 412.0
PSMD11 411.0
PSMA5 410.0
HAUS3 272.0
CCP110 260.0
ZWILCH 197.0
POT1 193.0
PPP1R12A 114.0
NUDC 91.0
CDC27 89.0
ANAPC7 43.0
NDC1 28.0
NUP155 -40.0
PPP2CA -89.0
PPP1CB -118.0
PSMB5 -134.0
DYNC1LI1 -141.0
CDKN2C -189.0
PSMC3IP -241.0
TUBB3 -261.0
CENPN -305.0
CHTF18 -318.0
UBE2E1 -331.0
H4C6 -340.0
CDK11B -347.0
RBBP4 -414.0
ODF2 -460.0
NCAPD3 -467.0
CDKN1B -509.0
TFDP2 -533.0
WAPL -534.0
NDE1 -565.0
TUBB1 -568.0
CCNB1 -600.0
BUB1 -631.0
UBC -640.0
SPAST -691.0
YWHAQ -694.0
NEK7 -729.0
POLD1 -744.0
DIDO1 -768.0
CDKN1A -800.0
TUBGCP4 -808.0
CCNE1 -881.0
CCNA1 -892.0
AHCTF1 -1001.0
PPP2R2A -1010.0
EP300 -1043.0
CEP290 -1045.0
FBXW11 -1172.0
MND1 -1216.0
PSMD13 -1223.0
MLH1 -1249.0
VRK1 -1255.0
LBR -1269.0
H2BC12 -1288.0
TPR -1291.0
MCM10 -1298.0
PPP2R5C -1316.0
BRIP1 -1317.0
VPS4A -1338.0
TERF2 -1342.0
PCBP4 -1355.0
NUP98 -1370.0
SMC4 -1405.0
NUP42 -1491.0
RBBP8 -1495.0
BUB3 -1503.0
H2AZ1 -1561.0
FBXL7 -1639.0
CDC7 -1658.0
CDC45 -1753.0
CENPQ -1771.0
PPP1CC -1773.0
NUP93 -1778.0
PCNT -1854.0
PRKCB -1916.0
POLE -2012.0
GINS3 -2028.0
H2BC4 -2033.0
CDK6 -2037.0
IST1 -2089.0
H3C10 -2100.0
DCTN1 -2108.0
RFC3 -2132.0
CDK5RAP2 -2164.0
SYCE3 -2165.0
GMNN -2214.0
SHQ1 -2221.0
PIAS4 -2245.0
PSME3 -2265.0
GORASP1 -2269.0
RPA1 -2286.0
H4C13 -2348.0
STAG1 -2377.0
CEP164 -2410.0
RCC2 -2441.0
CKAP5 -2537.0
NUP188 -2578.0
CENPP -2623.0
NME7 -2681.0
RSF1 -2688.0
CUL1 -2716.0
KIF2C -2754.0
NCAPG -2760.0
DYNC1I2 -2769.0
H4C12 -2774.0
UBE2C -2846.0
BRCA2 -2863.0
UBA52 -2875.0
PSMB7 -2995.0
NIPBL -3006.0
NOP10 -3018.0
RFC2 -3028.0
SMC2 -3038.0
PSME4 -3042.0
NINL -3062.0
CEP76 -3070.0
SUMO1 -3074.0
BTRC -3111.0
CDCA5 -3126.0
ANAPC5 -3127.0
KMT5A -3229.0
H4C9 -3283.0
NCAPG2 -3295.0
BABAM2 -3322.0
BANF1 -3329.0
H2AC6 -3373.0
PRKCA -3379.0
SMC1B -3421.0
CEP78 -3450.0
RUVBL1 -3452.0
LIN52 -3460.0
MNAT1 -3468.0
SFI1 -3491.0
CDT1 -3492.0
SRC -3509.0
NUP205 -3512.0
INCENP -3590.0
CCNA2 -3622.0
RRM2 -3706.0
CC2D1B -3711.0
ITGB3BP -3785.0
CHMP2A -3819.0
CDC25A -3836.0
POLR2F -3844.0
PSMA6 -3897.0
SFN -3911.0
PPP1R12B -3915.0
CLASP1 -3976.0
ATRIP -4017.0
SYNE2 -4074.0
SYCE2 -4102.0
OPTN -4164.0
SYCP3 -4219.0
PSMB2 -4270.0
LYN -4281.0
LIG1 -4363.0
POLR2L -4399.0
CENPF -4488.0
LPIN1 -4510.0
TUBA8 -4516.0
LIN54 -4537.0
SSNA1 -4575.0
TUBA1C -4583.0
NUP210 -4632.0
H4C5 -4637.0
UBE2V2 -4702.0
SGO2 -4765.0
SEM1 -4777.0
SEC13 -4820.0
ABL1 -4874.0
H4C4 -4917.0
POLD2 -4947.0
ORC3 -4974.0
HJURP -4981.0
NCAPH -5011.0
BLM -5013.0
PSMD8 -5041.0
RNF8 -5042.0
MSH5 -5061.0
H2AX -5114.0
DCTN3 -5120.0
RAD21 -5203.0
ANAPC15 -5225.0
PPME1 -5259.0
HAUS6 -5265.0
CABLES1 -5348.0
TMPO -5365.0
PSMF1 -5472.0
SDCCAG8 -5620.0
POLD3 -5644.0
TUBB2A -5696.0
MAD1L1 -5791.0
CENPW -5793.0
H2BC11 -5816.0
SMC3 -5831.0
LEMD2 -5864.0
NCAPH2 -5925.0
LMNB1 -5936.0
PSMD6 -5971.0
NUP43 -6011.0
TUBGCP5 -6056.0
LCMT1 -6073.0
TUBGCP6 -6161.0
MCM7 -6234.0
CENPU -6237.0
NSD2 -6354.0
TEN1 -6366.0
DYNC1H1 -6369.0
MAX -6513.0
GOLGA2 -6534.0
E2F6 -6574.0
TFDP1 -6580.0
POM121 -6621.0
AKT1 -6634.0
H2BC26 -6669.0
CEP131 -6715.0
LMNA -6719.0
MAPK1 -6741.0
H3-4 -6761.0
PSMB6 -6874.0
ORC5 -6898.0
TOPBP1 -6907.0
RMI2 -6927.0
CLIP1 -7030.0
CEP72 -7082.0
MCPH1 -7094.0
PRKAR2B -7133.0
TK1 -7156.0
UBE2D1 -7157.0
RAE1 -7253.0
SYCE1 -7284.0
POLR2J -7312.0
FZR1 -7345.0
ESCO2 -7391.0
MAPK3 -7453.0
TUBGCP2 -7550.0
POLR2A -7563.0
PKMYT1 -7590.0
H2BC1 -7617.0
LIN9 -7623.0
SYNE1 -7626.0
POM121C -7658.0
CENPJ -7669.0
DYNC1I1 -7779.0
PPP2R2D -7813.0
CSNK1D -8034.0
AKT2 -8044.0
CNTRL -8064.0
SUN1 -8090.0
AKT3 -8134.0
SYCP2 -8162.0
PHF20 -8195.0
PSME1 -8232.0
UBE2I -8350.0
MAU2 -8421.0
DCTN2 -8430.0
RFC1 -8464.0
ANKRD28 -8531.0
PPP2R1B -8545.0
JAK2 -8612.0
BIRC5 -8677.0
CHMP4C -8782.0
PPP6R3 -8816.0
CHMP6 -8868.0
RAD9A -9062.0
ACD -9149.5
PSMB11 -9151.0
RANGAP1 -9421.0
DYRK1A -9464.0
ANAPC2 -9497.0
TUBA3C -9626.0
POLE4 -9664.0
ESPL1 -9689.0
CSNK1E -9776.0
HERC2 -9847.0
TERT -9987.0
TUBAL3 -9995.0
KIF2B -10643.0
TUBA3D -10657.0
TUBA3E -11051.0



REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY

REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY
1486
set REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY
setSize 94
pANOVA 7.87e-11
s.dist 0.388
p.adjustANOVA 2.96e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS5 10401
RPL39L 10015
RPS13 10010
RPLP0 9720
EIF2S2 9447
RPL27 9406
RPL6 9269
ATF4 9235
RPL27A 8979
RPS28 8978
RPS8 8920
RPS12 8794
RPS25 8638
RPL19 8597
RPL9 8592
RPL12 8542
RPS6 8501
RPL41 8240
RPL18 8234
RPL10A 8175

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS5 10401.0
RPL39L 10015.0
RPS13 10010.0
RPLP0 9720.0
EIF2S2 9447.0
RPL27 9406.0
RPL6 9269.0
ATF4 9235.0
RPL27A 8979.0
RPS28 8978.0
RPS8 8920.0
RPS12 8794.0
RPS25 8638.0
RPL19 8597.0
RPL9 8592.0
RPL12 8542.0
RPS6 8501.0
RPL41 8240.0
RPL18 8234.0
RPL10A 8175.0
RPS2 8109.0
FAU 8086.0
RPL5 8055.0
RPL36AL 8033.5
RPS3A 7941.0
RPL23 7907.0
RPS18 7868.0
CEBPB 7763.0
RPL13 7712.0
RPS27A 7698.0
RPL13A 7489.5
ATF2 7405.0
RPLP2 7348.0
RPL3 7194.0
RPL4 7148.0
RPS26 6957.0
RPL38 6914.0
RPS21 6901.0
RPL35A 6893.0
RPL21 6804.0
EIF2S1 6710.0
RPL28 6441.0
TRIB3 6151.0
RPL34 6124.0
RPL7 6080.0
RPL17 6034.0
RPS29 5882.0
RPS15 5697.0
DDIT3 5545.0
RPL18A 5467.0
RPL32 5357.0
RPS15A 5210.0
RPS10 5051.0
RPS19 5043.0
RPL35 4765.0
RPS20 4727.0
CEBPG 3796.0
RPSA 3658.0
RPL26L1 3215.0
RPL8 3119.0
ATF3 3009.0
EIF2AK4 2874.0
RPS24 2748.0
RPL30 2631.0
RPL37 2527.0
RPS16 2475.0
RPL11 2329.0
RPS27L 2308.0
RPS23 2004.0
RPL36 1365.0
RPS11 1269.0
ASNS 1195.0
RPS27 1132.0
RPLP1 792.0
RPL22 440.0
RPS14 322.0
RPL24 57.0
RPL14 -57.0
RPS3 -850.0
RPL23A -1287.0
RPL15 -1589.0
RPS9 -1972.0
UBA52 -2875.0
RPS7 -3608.0
RPL3L -4519.0
RPL29 -4767.0
IMPACT -4922.0
RPL37A -5673.0
RPL7A -5783.0
RPL22L1 -6323.0
RPL26 -6909.0
GCN1 -8547.0
RPL31 -8668.0
RPL10L -10702.0



REACTOME_EUKARYOTIC_TRANSLATION_INITIATION

REACTOME_EUKARYOTIC_TRANSLATION_INITIATION
1149
set REACTOME_EUKARYOTIC_TRANSLATION_INITIATION
setSize 110
pANOVA 9.02e-11
s.dist 0.358
p.adjustANOVA 2.96e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS5 10401
RPL39L 10015
RPS13 10010
EIF2B1 9802
RPLP0 9720
EIF2S2 9447
RPL27 9406
RPL6 9269
RPL27A 8979
RPS28 8978
RPS8 8920
EIF3J 8894
RPS12 8794
RPS25 8638
RPL19 8597
RPL9 8592
RPL12 8542
RPS6 8501
EIF2B5 8376
EIF2B2 8327

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS5 10401.0
RPL39L 10015.0
RPS13 10010.0
EIF2B1 9802.0
RPLP0 9720.0
EIF2S2 9447.0
RPL27 9406.0
RPL6 9269.0
RPL27A 8979.0
RPS28 8978.0
RPS8 8920.0
EIF3J 8894.0
RPS12 8794.0
RPS25 8638.0
RPL19 8597.0
RPL9 8592.0
RPL12 8542.0
RPS6 8501.0
EIF2B5 8376.0
EIF2B2 8327.0
EIF3E 8280.0
RPL41 8240.0
RPL18 8234.0
RPL10A 8175.0
RPS2 8109.0
FAU 8086.0
RPL5 8055.0
RPL36AL 8033.5
RPS3A 7941.0
RPL23 7907.0
RPS18 7868.0
RPL13 7712.0
RPS27A 7698.0
EIF4A1 7576.0
EIF5 7520.0
RPL13A 7489.5
RPLP2 7348.0
RPL3 7194.0
RPL4 7148.0
RPS26 6957.0
RPL38 6914.0
RPS21 6901.0
RPL35A 6893.0
RPL21 6804.0
EIF2S1 6710.0
RPL28 6441.0
RPL34 6124.0
RPL7 6080.0
RPL17 6034.0
RPS29 5882.0
RPS15 5697.0
RPL18A 5467.0
RPL32 5357.0
RPS15A 5210.0
RPS10 5051.0
RPS19 5043.0
RPL35 4765.0
RPS20 4727.0
EIF4A2 4483.0
EIF4B 4211.0
RPSA 3658.0
EIF3F 3644.0
EIF4E 3532.0
EIF3L 3274.0
RPL26L1 3215.0
RPL8 3119.0
EIF3I 2811.0
RPS24 2748.0
RPL30 2631.0
EIF3K 2561.0
RPL37 2527.0
EIF3A 2478.0
RPS16 2475.0
RPL11 2329.0
RPS27L 2308.0
RPS23 2004.0
EIF2B4 1579.0
RPL36 1365.0
RPS11 1269.0
EIF5B 1241.0
RPS27 1132.0
RPLP1 792.0
RPL22 440.0
RPS14 322.0
RPL24 57.0
RPL14 -57.0
EIF3G -63.0
EIF2B3 -195.0
EIF3M -282.0
EIF4EBP1 -387.0
RPS3 -850.0
RPL23A -1287.0
RPL15 -1589.0
RPS9 -1972.0
EIF4G1 -2605.0
EIF3D -2839.0
UBA52 -2875.0
RPS7 -3608.0
EIF3H -3811.0
RPL3L -4519.0
RPL29 -4767.0
EIF3B -4859.0
EIF4H -5301.0
RPL37A -5673.0
RPL7A -5783.0
PABPC1 -5994.0
RPL22L1 -6323.0
RPL26 -6909.0
RPL31 -8668.0
RPL10L -10702.0



REACTOME_CELLULAR_RESPONSES_TO_STIMULI

REACTOME_CELLULAR_RESPONSES_TO_STIMULI
1314
set REACTOME_CELLULAR_RESPONSES_TO_STIMULI
setSize 779
pANOVA 4.02e-10
s.dist 0.132
p.adjustANOVA 9.42e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C12 10715
TUBB8 10699
H2BC14 10635
H2AC14 10619
TUBB4B 10590
CCL2 10585
PREB 10518
H2BC6 10447
HBA1 10441
MEF2D 10418
RPS5 10401
KPTN 10376
H2BC17 10375
MT1E 10325
DYNLL2 10298
H4C1 10268
H2AC4 10244
COX14 10198
H3C1 10183
LAMTOR5 10174

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C12 10715.0
TUBB8 10699.0
H2BC14 10635.0
H2AC14 10619.0
TUBB4B 10590.0
CCL2 10585.0
PREB 10518.0
H2BC6 10447.0
HBA1 10441.0
MEF2D 10418.0
RPS5 10401.0
KPTN 10376.0
H2BC17 10375.0
MT1E 10325.0
DYNLL2 10298.0
H4C1 10268.0
H2AC4 10244.0
COX14 10198.0
H3C1 10183.0
LAMTOR5 10174.0
CREB3L4 10157.0
CREB3L1 10047.0
ATP6V0C 10039.0
RPL39L 10015.0
RPS13 10010.0
H3C6 9987.0
ERF 9911.0
PSMB8 9883.0
SYVN1 9818.0
P4HB 9800.0
BAG4 9761.0
RPLP0 9720.0
UBE2S 9716.0
CREB3L3 9679.0
HSPB2 9644.0
H3C2 9609.0
HSPA2 9602.0
TINF2 9588.0
GPX8 9555.0
HSP90B1 9551.0
FOS 9527.0
CDK4 9521.0
JUN 9518.0
HMGA1 9511.0
ETS2 9496.0
MT2A 9469.0
EXOSC5 9460.0
EIF2S2 9447.0
PSMC1 9440.0
RPL27 9406.0
CSNK2A1 9373.0
RPL6 9269.0
H3C8 9237.0
ATF4 9235.0
H2AJ 9219.0
CDC26 9208.0
COX6A1 9203.0
PRDX6 9188.0
SERP1 9116.0
MDM2 9066.0
ST13 9026.0
CA9 9006.0
RPL27A 8979.0
RPS28 8978.0
IL6 8975.0
CDKN2B 8957.0
COX16 8939.0
H4C3 8934.0
RPS8 8920.0
ATP6V0E1 8919.0
HSPA8 8896.0
ATP6V1F 8870.0
COX11 8860.0
SIN3A 8850.0
RBX1 8801.0
RPS12 8794.0
H4C8 8774.0
CITED2 8769.0
EXOSC8 8764.0
H2AC20 8751.0
SP1 8660.0
RPS25 8638.0
PSMD4 8637.0
CRTC2 8608.0
RPL19 8597.0
RPL9 8592.0
MT1H 8582.0
TUBA4B 8566.0
PSME2 8563.0
GPX1 8559.0
RPL12 8542.0
IL1A 8541.0
RPS6 8501.0
H1-1 8495.0
ATP6V1G1 8473.0
PSMD7 8416.0
SKP1 8408.0
TUBB2B 8395.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
HERPUD1 8358.0
H3-3B 8344.0
MT1M 8337.0
CAPZA3 8288.0
TP53 8272.0
TUBA4A 8265.0
PSMB3 8251.0
RPL41 8240.0
RPL18 8234.0
EXOSC9 8176.0
RPL10A 8175.0
AQP8 8164.0
RPS2 8109.0
NUP153 8090.0
FAU 8086.0
CASTOR1 8069.0
RPL5 8055.0
RPL36AL 8033.5
ID1 8021.0
TACO1 8003.0
H1-3 7994.0
H2BC9 7978.5
H3C7 7978.5
RPS3A 7941.0
FKBP14 7934.0
NUP58 7912.0
PRDX3 7909.0
RPL23 7907.0
PSMC6 7899.0
RPS18 7868.0
MRPL18 7849.0
KDELR3 7841.0
RB1 7836.0
H2BC21 7828.0
ATF5 7816.0
DNAJB11 7804.0
IDH1 7781.0
CEBPB 7763.0
LIMD1 7762.0
ANAPC11 7732.0
CBX8 7728.0
LAMTOR2 7721.0
RPL13 7712.0
RPS27A 7698.0
XPO1 7679.0
HDGF 7665.0
MYC 7649.0
AJUBA 7627.0
NBN 7592.0
VHL 7555.0
H2AC18 7550.5
H2AC19 7550.5
HSPA1B 7503.0
RPL13A 7489.5
ATF2 7405.0
DCTN6 7356.0
RPLP2 7348.0
UBB 7319.0
H3C4 7298.0
RPS19BP1 7260.0
RPL3 7194.0
TUBA1B 7189.0
E2F1 7180.0
BMT2 7163.0
RPL4 7148.0
PRDX2 7131.0
MAPKAPK5 7097.0
NQO1 7068.0
DNAJA2 7045.0
PSMC3 7021.0
SKP2 7007.0
TUBB4A 7002.0
ACTR1A 6970.0
RPS26 6957.0
HSPA5 6949.0
RPL38 6914.0
RPS21 6901.0
RPL35A 6893.0
TGS1 6886.0
PSMB9 6881.0
CREBRF 6846.0
MT1A 6839.0
H2BC3 6830.0
RPL21 6804.0
PSMA2 6802.0
EIF2S1 6710.0
CREB3 6706.0
CDC16 6674.0
CBX4 6634.0
H2BC5 6618.0
TNRC6C 6608.0
MDM4 6604.0
CDKN2D 6595.0
ATP6V1G2 6585.0
HSBP1 6579.0
HIF1A 6555.0
ETS1 6552.0
TERF2IP 6545.0
LAMTOR4 6497.0
H2AZ2 6467.0
RPL28 6441.0
COX8A 6428.0
MT1F 6345.0
ANAPC16 6333.0
KDM6B 6330.0
UBE2D3 6315.0
NUDT2 6246.0
NUP214 6207.0
HSPA6 6193.0
NUP88 6185.0
TRIB3 6151.0
MAPK10 6150.0
RPL34 6124.0
RRAGC 6100.0
RPL7 6080.0
NUP160 6067.0
RPL17 6034.0
ATP6V1C1 6032.0
SCO1 6031.0
H2BC10 6026.0
HIKESHI 6007.0
ATP6V1E1 6001.0
PSMD12 5909.0
ATP6V1B1 5902.0
GSK3A 5894.0
RPS29 5882.0
NFKB1 5873.0
STAT3 5799.0
PSMA3 5797.0
PSMC2 5730.0
HSPA14 5722.0
PSMA1 5699.0
RPS15 5697.0
TNRC6B 5666.0
PRDX5 5643.0
HMOX2 5631.0
SMARCD3 5619.0
RANBP2 5556.0
DDIT3 5545.0
CRYAB 5540.0
NUP62 5513.0
PSMB4 5511.0
NUP35 5491.0
RPL18A 5467.0
PSMA7 5457.0
UBE2D2 5455.0
DNAJC7 5402.0
NUP107 5390.0
RPL32 5357.0
PSMC5 5252.0
SEH1L 5251.0
DEDD2 5213.0
RPS15A 5210.0
H3C11 5197.0
ATR 5120.0
CHD9 5118.0
RPS10 5051.0
RPS19 5043.0
TATDN2 5009.0
ATP6V1A 5003.0
HSP90AA1 4971.0
PSMA4 4968.0
CREB1 4963.0
GPX7 4950.0
TXNRD2 4885.0
NR3C1 4868.0
CTDSP2 4861.0
CYBA 4856.0
TXN 4768.0
RPL35 4765.0
RPS20 4727.0
HSP90AB1 4714.0
ACTR10 4678.0
ATM 4677.0
MAPK14 4661.0
HSPA13 4658.0
MAP2K7 4584.0
AGO3 4561.0
DNAJB9 4553.0
E2F2 4524.0
PTK6 4508.0
H2BC15 4475.0
EGLN2 4466.0
HSPB8 4444.0
ACADVL 4394.0
NDUFA4 4368.0
HSPA4 4356.0
ELOC 4336.0
UFD1 4333.0
WDR59 4304.0
MAFG 4290.0
MBTPS1 4287.0
PPP2R5B 4283.0
ARNT 4269.0
NUP37 4196.0
PSMD3 4188.0
CSNK2A2 4101.0
DYNC1LI2 4052.0
XBP1 4035.0
NR3C2 4018.0
RAD50 3962.0
CDC23 3912.0
TERF1 3891.0
EEF1A1 3873.0
ATP6V1D 3847.0
HSPA1A 3836.0
ANAPC10 3818.0
TUBB6 3809.0
CEBPG 3796.0
BLVRB 3779.0
RPSA 3658.0
H1-4 3625.0
NUP54 3624.0
CDK2 3557.0
ELOB 3538.0
NUP85 3458.0
AKT1S1 3446.0
COX6B1 3402.0
PSMC4 3370.0
RPA3 3368.0
NUP50 3335.0
COX5A 3323.0
PRDX1 3266.0
ADD1 3246.0
PSMD1 3237.0
RPL26L1 3215.0
H2BC8 3188.0
ATP6V1H 3174.0
CBX2 3150.0
RPL8 3119.0
H2AC8 3039.0
TPP1 3030.0
ATF3 3009.0
NOX5 2969.0
MAP1LC3B 2964.0
COX7A2L 2957.0
CDKN2A 2953.0
RELA 2935.0
E2F3 2886.0
NUP133 2881.0
EIF2AK4 2874.0
ANAPC4 2868.0
KHSRP 2866.0
PSMD5 2770.0
NRIP1 2765.0
RPS24 2748.0
NR1D1 2747.0
DNAJA1 2740.0
NFYC 2732.0
ANAPC1 2721.0
NFYB 2667.0
HMOX1 2653.0
RPL30 2631.0
H1-0 2597.0
TUBA1A 2579.0
RPL37 2527.0
RPS16 2475.0
CSNK2B 2449.0
CAPZA1 2409.0
H4C16 2382.0
RPL11 2329.0
CHAC1 2320.0
RPS27L 2308.0
H3C3 2303.0
PPP1R15A 2297.0
GSK3B 2248.0
BRCA1 2223.0
ATP6V0E2 2205.0
EIF2AK1 2203.0
ATOX1 2192.0
AAAS 2175.0
SHC1 2151.0
PSMB10 2137.0
CYCS 2106.0
COX5B 2064.0
RPS23 2004.0
HSPA4L 1944.0
MYDGF 1939.0
DCTN5 1864.0
TXNRD1 1836.0
DNAJC2 1823.0
DNAJB1 1794.0
CCS 1772.0
SQSTM1 1750.0
SOD1 1728.0
HSPB1 1700.0
PSMB1 1698.0
BAG5 1642.0
HYOU1 1565.0
DYNLL1 1562.0
FKBP4 1540.0
GRB10 1463.0
RPA2 1446.0
NCOA2 1402.0
NOX4 1391.0
RPL36 1365.0
KICS2 1359.0
MRE11 1313.0
EIF2AK3 1303.0
BLVRA 1292.0
H4C2 1279.0
RPS11 1269.0
PSMA8 1258.0
PSMD2 1209.0
TNFRSF21 1207.0
ASNS 1195.0
YWHAE 1143.0
RPS27 1132.0
H4C11 1080.0
PSMD9 1039.0
TXNIP 1032.0
NPRL2 907.0
RNF2 899.0
H1-5 879.0
HMGA2 830.0
H2BC13 823.0
PSMD14 794.0
RPLP1 792.0
HIGD1A 731.0
TLN1 686.0
FNIP1 680.0
CCNE2 668.0
BAG1 647.0
KAT5 642.0
KEAP1 640.0
SESN1 639.0
COX19 623.0
EGLN1 561.0
MT1X 560.0
RPL22 440.0
WIPI1 425.0
PSMD11 411.0
PSMA5 410.0
RPS14 322.0
POT1 193.0
GCLM 123.0
CDC27 89.0
CAT 83.0
RPL24 57.0
MIOS 56.0
ANAPC7 43.0
SESN2 31.0
NDC1 28.0
TBL1XR1 0.0
NUP155 -40.0
RPL14 -57.0
UBXN7 -98.0
APOB -110.0
PSMB5 -134.0
DYNC1LI1 -141.0
CDKN2C -189.0
ARFGAP1 -233.0
ME1 -250.0
TUBB3 -261.0
NFYA -287.0
MUL1 -292.0
RXRA -296.0
UBE2E1 -331.0
H4C6 -340.0
COX18 -399.0
RBBP4 -414.0
PDIA6 -447.0
EDEM1 -491.0
CDKN1B -509.0
COX20 -511.0
TFDP2 -533.0
TUBB1 -568.0
MT4 -575.0
UBC -640.0
CLOCK -658.0
CAMK2D -728.0
EXOSC1 -737.0
CRTC1 -752.0
CDKN1A -800.0
CAMK2G -811.0
RPS3 -850.0
HELZ2 -853.0
CCNE1 -881.0
EPO -883.0
CCNA1 -892.0
USP46 -909.0
SRPRA -926.0
ATP6V1B2 -999.0
KLHDC3 -1026.0
EP300 -1043.0
SUZ12 -1050.0
EXOSC2 -1111.0
PALB2 -1138.0
SERPINH1 -1176.0
PSMD13 -1223.0
NCOA6 -1244.0
RPL23A -1287.0
H2BC12 -1288.0
TPR -1291.0
TERF2 -1342.0
TCIRG1 -1360.0
NUP98 -1370.0
DIS3 -1418.0
EPAS1 -1422.0
GFPT1 -1448.0
MAPK8 -1449.0
CUL2 -1490.0
NUP42 -1491.0
MAP3K5 -1527.0
H2AZ1 -1561.0
RPL15 -1589.0
GPX6 -1667.0
ATP6V1C2 -1710.0
CARM1 -1729.0
SH3BP4 -1751.0
LAMTOR3 -1769.0
MAPK7 -1772.0
COX4I1 -1776.0
NUP93 -1778.0
PPARGC1A -1810.0
ATF6 -1865.0
FNIP2 -1921.0
RPS9 -1972.0
SOD2 -2013.0
ABCC1 -2018.0
H2BC4 -2033.0
CDK6 -2037.0
SRPRB -2045.0
TRIM21 -2068.0
H3C10 -2100.0
DCTN1 -2108.0
TXN2 -2143.0
NCOA1 -2153.0
HDAC3 -2207.0
PSME3 -2265.0
PGR -2281.0
RPA1 -2286.0
PDIA5 -2324.0
H4C13 -2348.0
NFE2L2 -2368.0
EHMT2 -2398.0
PRKCD -2402.0
MAP2K3 -2469.0
UBN1 -2510.0
EXOSC6 -2529.0
RRAGD -2541.0
NUP188 -2578.0
AGO1 -2599.0
SIRT1 -2694.0
EXOSC7 -2703.0
EXOSC3 -2706.0
CUL1 -2716.0
CLEC1B -2745.0
DYNC1I2 -2769.0
H4C12 -2774.0
ERO1A -2789.0
TKT -2821.0
CREB3L2 -2838.0
UBE2C -2846.0
GSTA1 -2856.0
UBA52 -2875.0
HSPH1 -2882.0
CXXC1 -2904.0
RPS6KA2 -2916.0
PSMB7 -2995.0
MAPKAPK2 -3023.0
PSME4 -3042.0
EXOSC4 -3047.0
BTRC -3111.0
ANAPC5 -3127.0
MAP4K4 -3146.0
HIRA -3187.0
SOD3 -3222.0
IGFBP1 -3241.0
H4C9 -3283.0
HBB -3334.0
H2AC6 -3373.0
HSPA9 -3389.0
FBXL17 -3405.0
CAPZA2 -3425.0
MAPK11 -3435.0
MEF2C -3436.0
GPX3 -3443.0
DNAJB6 -3463.0
BAG3 -3474.0
EHMT1 -3490.0
NUP205 -3512.0
APOA1 -3516.0
GOSR2 -3557.0
EZH2 -3560.0
PGD -3567.0
RORA -3581.0
RPS7 -3608.0
PHC3 -3621.0
CCNA2 -3622.0
WTIP -3642.0
EED -3682.0
GML -3704.0
NCOR1 -3721.0
TALDO1 -3722.0
VCP -3748.0
GCLC -3764.0
ASF1A -3776.0
SURF1 -3822.0
PSMA6 -3897.0
RPTOR -3900.0
PTGES3 -3960.0
NPLOC4 -3978.0
VEGFA -3998.0
STIP1 -4021.0
NLRP3 -4141.0
YIF1A -4169.0
RLN1 -4175.0
PSMB2 -4270.0
NCF2 -4279.0
HSPA12A -4351.0
MLST8 -4487.0
GSR -4493.0
HIF1AN -4503.0
TUBA8 -4516.0
RPL3L -4519.0
BMI1 -4555.0
MT3 -4572.0
TUBA1C -4583.0
NUP210 -4632.0
H4C5 -4637.0
RRAGA -4638.0
HSPA12B -4652.0
DCP2 -4756.0
RPL29 -4767.0
SEM1 -4777.0
SIN3B -4783.0
SEC13 -4820.0
PHC1 -4846.0
DCSTAMP -4858.0
H4C4 -4917.0
IMPACT -4922.0
MAP2K6 -4983.0
PSMD8 -5041.0
H2AX -5114.0
DCTN3 -5120.0
ANAPC15 -5225.0
GPX5 -5240.0
MTOR -5272.0
SEC31A -5289.0
MAP2K4 -5319.0
STAP2 -5366.0
CABIN1 -5379.0
TNRC6A -5391.0
EXTL2 -5411.0
PSMF1 -5472.0
ATP6V1G3 -5643.0
RPL37A -5673.0
TUBB2A -5696.0
TNIK -5734.0
PARN -5744.0
RPL7A -5783.0
H2BC11 -5816.0
SCMH1 -5843.0
DNAJA4 -5868.0
FKBP5 -5909.0
SZT2 -5917.0
EGLN3 -5924.0
LMNB1 -5936.0
PSMD6 -5971.0
CAPZB -5987.0
NUP43 -6011.0
ATP6V0D2 -6012.0
NCF4 -6016.0
RAI1 -6025.0
MAPK9 -6159.0
HSPA1L -6191.0
FABP1 -6221.0
HM13 -6236.0
LRPPRC -6245.0
MAFK -6300.0
RPL22L1 -6323.0
DYNC1H1 -6369.0
VENTX -6394.0
DNAJC3 -6423.0
MIR24-2 -6429.0
HIF3A -6442.0
ATP6V0D1 -6451.0
MT1G -6492.0
TFDP1 -6580.0
SNCB -6582.0
POM121 -6621.0
MED1 -6624.0
AKT1 -6634.0
H2BC26 -6669.0
ALB -6677.0
LMNA -6719.0
MAPK1 -6741.0
ATP6V0B -6755.0
H3-4 -6761.0
H1-2 -6818.0
NCOR2 -6856.0
AGO4 -6858.0
PSMB6 -6874.0
CUL7 -6903.0
RPL26 -6909.0
IGFBP7 -6938.0
CCAR2 -7003.0
EP400 -7039.0
RPS6KA1 -7053.0
BAG2 -7085.0
UBE2D1 -7157.0
CREBBP -7206.0
CAMK2B -7212.0
SSR1 -7224.0
CSRP1 -7234.0
RAE1 -7253.0
CXCL8 -7325.0
PPARA -7329.0
FZR1 -7345.0
COX7C -7372.0
EXTL3 -7373.0
CAMK2A -7375.0
PHC2 -7388.0
SRXN1 -7432.0
CALR -7434.0
MAPK3 -7453.0
RING1 -7507.0
SLC38A9 -7574.0
NPAS2 -7610.0
H2BC1 -7617.0
POM121C -7658.0
COX6C -7672.0
DCTN4 -7674.0
MTF1 -7699.0
HSF1 -7766.0
HBA2 -7771.0
DYNC1I1 -7779.0
WFS1 -7911.0
DEPDC5 -8029.0
ATP6V1E2 -8031.0
AKT2 -8044.0
EXTL1 -8128.0
AKT3 -8134.0
CUL3 -8184.0
SLC46A1 -8201.0
PSME1 -8232.0
RHEB -8364.0
DCTN2 -8430.0
FLCN -8451.0
NOTCH1 -8493.0
IFNB1 -8500.0
GSTP1 -8506.0
MOV10 -8523.0
GCN1 -8547.0
DPP3 -8571.0
MAPKAPK3 -8611.0
SLC7A11 -8666.0
RPL31 -8668.0
GSTA3 -8687.0
MT1B -8759.0
NPRL3 -8786.0
BACH1 -8914.0
ITFG2 -8951.0
BMAL1 -8988.0
GPX2 -9101.0
ACD -9149.5
PSMB11 -9151.0
TLR4 -9157.0
CBX6 -9190.0
SCO2 -9255.0
CRTC3 -9365.0
WDR24 -9433.0
ZBTB17 -9463.0
ANAPC2 -9497.0
ERN1 -9529.0
LAMTOR1 -9552.0
MINK1 -9605.0
TUBA3C -9626.0
PLA2G4B -9747.0
TUBAL3 -9995.0
LY96 -10282.0
TUBA3D -10657.0
RPL10L -10702.0
CRYBA4 -10831.0
DDX11 -10894.0
MIR24-1 -10931.0
TUBA3E -11051.0



REACTOME_INFLUENZA_INFECTION

REACTOME_INFLUENZA_INFECTION
228
set REACTOME_INFLUENZA_INFECTION
setSize 149
pANOVA 4.02e-10
s.dist 0.297
p.adjustANOVA 9.42e-08



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS5 10401
RPL39L 10015
RPS13 10010
RPLP0 9720
RPL27 9406
KPNA7 9394
RPL6 9269
POLR2K 9241
ISG15 9231
RPL27A 8979
RPS28 8978
POLR2C 8943
RPS8 8920
RPS12 8794
RPS25 8638
RPL19 8597
RPL9 8592
RPL12 8542
RPS6 8501
RPL41 8240

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS5 10401.0
RPL39L 10015.0
RPS13 10010.0
RPLP0 9720.0
RPL27 9406.0
KPNA7 9394.0
RPL6 9269.0
POLR2K 9241.0
ISG15 9231.0
RPL27A 8979.0
RPS28 8978.0
POLR2C 8943.0
RPS8 8920.0
RPS12 8794.0
RPS25 8638.0
RPL19 8597.0
RPL9 8592.0
RPL12 8542.0
RPS6 8501.0
RPL41 8240.0
RPL18 8234.0
POLR2D 8181.0
RPL10A 8175.0
RPS2 8109.0
NUP153 8090.0
FAU 8086.0
RPL5 8055.0
RPL36AL 8033.5
RPS3A 7941.0
NUP58 7912.0
RPL23 7907.0
RPS18 7868.0
RPL13 7712.0
RPS27A 7698.0
XPO1 7679.0
PARP1 7668.0
RPL13A 7489.5
RPLP2 7348.0
GRSF1 7248.0
RPL3 7194.0
RPL4 7148.0
RPS26 6957.0
RPL38 6914.0
RPS21 6901.0
RPL35A 6893.0
RAN 6824.0
RPL21 6804.0
RPL28 6441.0
GTF2F1 6376.0
NUP214 6207.0
NUP88 6185.0
KPNA5 6135.0
RPL34 6124.0
RPL7 6080.0
POLR2I 6073.0
NUP160 6067.0
RPL17 6034.0
KPNB1 5988.0
RPS29 5882.0
RPS15 5697.0
RANBP2 5556.0
NUP62 5513.0
NUP35 5491.0
RPL18A 5467.0
NUP107 5390.0
RPL32 5357.0
SEH1L 5251.0
RPS15A 5210.0
RPS10 5051.0
RPS19 5043.0
CLTC 4979.0
HSP90AA1 4971.0
POLR2H 4937.0
RPL35 4765.0
RPS20 4727.0
NUP37 4196.0
EIF2AK2 3925.0
HSPA1A 3836.0
RPSA 3658.0
NUP54 3624.0
KPNA4 3473.0
NUP85 3458.0
POLR2B 3342.0
NUP50 3335.0
RPL26L1 3215.0
RPL8 3119.0
NUP133 2881.0
KPNA2 2875.0
POLR2G 2774.0
RPS24 2748.0
RPL30 2631.0
RPL37 2527.0
RPS16 2475.0
RPL11 2329.0
RPS27L 2308.0
GTF2F2 2212.0
AAAS 2175.0
RPS23 2004.0
POLR2E 1875.0
PABPN1 1738.0
CLTA 1471.0
RPL36 1365.0
RPS11 1269.0
KPNA3 1168.0
RPS27 1132.0
RPLP1 792.0
CPSF4 582.0
RPL22 440.0
TGFB1 382.0
RPS14 322.0
RPL24 57.0
NDC1 28.0
NUP155 -40.0
RPL14 -57.0
RPS3 -850.0
RPL23A -1287.0
TPR -1291.0
NUP98 -1370.0
NUP42 -1491.0
RPL15 -1589.0
NUP93 -1778.0
RPS9 -1972.0
NUP188 -2578.0
UBA52 -2875.0
KPNA1 -3430.0
NUP205 -3512.0
RPS7 -3608.0
POLR2F -3844.0
POLR2L -4399.0
RPL3L -4519.0
NUP210 -4632.0
RPL29 -4767.0
SEC13 -4820.0
CANX -5159.0
IPO5 -5271.0
RPL37A -5673.0
RPL7A -5783.0
NUP43 -6011.0
RPL22L1 -6323.0
DNAJC3 -6423.0
POM121 -6621.0
RPL26 -6909.0
RAE1 -7253.0
POLR2J -7312.0
CALR -7434.0
POLR2A -7563.0
POM121C -7658.0
RPL31 -8668.0
RPL10L -10702.0



REACTOME_INFECTIOUS_DISEASE

REACTOME_INFECTIOUS_DISEASE
974
set REACTOME_INFECTIOUS_DISEASE
setSize 910
pANOVA 6.72e-10
s.dist 0.121
p.adjustANOVA 1.38e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
CD3G 10726
H3C12 10715
TUBB8 10699
LCK 10681
H2BC14 10635
H2AC14 10619
CD8B 10596
TUBB4B 10590
HLA-F 10555
GNGT2 10497
H2BC6 10447
FXYD7 10430
RPS5 10401
H2BC17 10375
CBX1 10337
HLA-B 10303
DYNLL2 10298
H4C1 10268
MEFV 10266
H2AC4 10244

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CD3G 10726.0
H3C12 10715.0
TUBB8 10699.0
LCK 10681.0
H2BC14 10635.0
H2AC14 10619.0
CD8B 10596.0
TUBB4B 10590.0
HLA-F 10555.0
GNGT2 10497.0
H2BC6 10447.0
FXYD7 10430.0
RPS5 10401.0
H2BC17 10375.0
CBX1 10337.0
HLA-B 10303.0
DYNLL2 10298.0
H4C1 10268.0
MEFV 10266.0
H2AC4 10244.0
GNAS 10206.0
SAP30 10201.0
H3C1 10183.0
HLA-E 10167.0
ACTB 10161.0
CXCR4 10063.0
IFNA5 10052.0
TAF10 10038.0
RPL39L 10015.0
RPS13 10010.0
SDC3 10002.0
VPS36 10000.0
H3C6 9987.0
PYCARD 9962.0
B2M 9954.0
GNG8 9932.0
WASF1 9903.0
CD79A 9902.0
PSMB8 9883.0
SNRPD2 9776.0
RPLP0 9720.0
CORO1A 9713.0
YWHAH 9707.0
IFNA21 9663.0
SUGT1 9634.0
H3C2 9609.0
ISCU 9607.0
ACTR3 9606.0
GEMIN7 9544.0
SIGMAR1 9541.0
JUN 9518.0
HMGA1 9511.0
GTF2H3 9509.0
TAF6 9485.0
GEMIN2 9444.0
PSMC1 9440.0
PARP10 9434.0
TOMM70 9433.0
ACTG1 9424.0
RPL27 9406.0
TRIM28 9401.0
KPNA7 9394.0
SMAD4 9393.0
RIPK3 9358.0
SNRPF 9329.0
REST 9290.0
RPL6 9269.0
POLR2K 9241.0
H3C8 9237.0
ISG15 9231.0
STX1A 9223.0
SFPQ 9174.0
ANO8 9155.0
VPS37D 9126.0
TLR9 9120.0
NFKBIA 9057.0
TCEA1 9025.0
RPL27A 8979.0
RPS28 8978.0
IL6 8975.0
IFNA16 8968.0
POLR2C 8943.0
SNRPD3 8937.0
H4C3 8934.0
RPS8 8920.0
LIG4 8915.0
SERPINE1 8895.0
RBX1 8801.0
RPS12 8794.0
TUBB 8793.0
NLRP12 8788.0
PRKACB 8775.0
H4C8 8774.0
HNRNPA1 8761.0
SUPT4H1 8759.0
H2AC20 8751.0
H2AC17 8748.0
NT5E 8667.0
SP1 8660.0
TAF9 8654.0
IRAK2 8653.0
RPS25 8638.0
PSMD4 8637.0
RPL19 8597.0
TAF11 8593.0
RPL9 8592.0
TUBA4B 8566.0
PSME2 8563.0
RPL12 8542.0
IL1A 8541.0
RPS6 8501.0
PTPN11 8498.0
IL17RC 8494.0
ARPC3 8491.0
SMN1 8480.5
SMN2 8480.5
VPS33B 8468.0
PSMD7 8416.0
CAV1 8413.0
SKP1 8408.0
TUBB2B 8395.0
H2AC7 8363.5
H2BC7 8363.5
HMG20B 8284.0
AP1M2 8277.0
TUBA4A 8265.0
PKLR 8264.0
PSMB3 8251.0
RPL41 8240.0
RPL18 8234.0
GUCY2C 8226.0
GSDMD 8210.0
POLR2D 8181.0
RPL10A 8175.0
RPS2 8109.0
SUPT16H 8100.0
NUP153 8090.0
FAU 8086.0
RPL5 8055.0
MGAT2 8033.5
RPL36AL 8033.5
H2BC9 7978.5
H3C7 7978.5
RPS3A 7941.0
NUP58 7912.0
RPL23 7907.0
PSMC6 7899.0
RPS18 7868.0
STX1B 7862.0
RB1 7836.0
H2BC21 7828.0
RPL13 7712.0
RPS27A 7698.0
RPN2 7689.0
XPO1 7679.0
PARP1 7668.0
MAVS 7593.0
VHL 7555.0
H2AC18 7550.5
H2AC19 7550.5
RNMT 7539.0
H2AC15 7513.0
RPL13A 7489.5
IRF3 7433.0
ZCRB1 7361.0
RPLP2 7348.0
UBB 7319.0
S1PR1 7309.0
H3C4 7298.0
PDCD1 7289.0
DDX20 7263.0
GRSF1 7248.0
RPL3 7194.0
TUBA1B 7189.0
RCAN3 7184.0
UBE2V1 7164.0
BLNK 7152.0
RPL4 7148.0
SV2B 7146.0
G3BP1 7074.0
XRCC6 7048.0
MGAT5 7038.0
PSMC3 7021.0
TUBB4A 7002.0
RPS26 6957.0
DAD1 6950.0
NCKAP1 6948.0
ABI1 6929.0
PPIA 6915.0
RPL38 6914.0
RPS21 6901.0
VAMP2 6897.0
RPL35A 6893.0
HDAC2 6890.0
PSMB9 6881.0
FXYD3 6833.0
H2BC3 6830.0
RAN 6824.0
RPL21 6804.0
PSMA2 6802.0
HDAC1 6791.0
HLA-A 6738.0
MYO1C 6734.0
CHMP2B 6689.0
YWHAB 6683.0
FXYD2 6677.0
CNBP 6667.0
SDC2 6638.0
ATP1B2 6622.0
H2BC5 6618.0
LTF 6590.0
TAF12 6560.0
MGAT4A 6473.0
RPL28 6441.0
SH3GL2 6435.0
CHMP5 6392.0
GTF2F1 6376.0
CD247 6331.0
SEC23A 6245.0
SV2C 6222.0
NUP214 6207.0
CSNK1A1 6188.0
IFIH1 6187.0
NUP88 6185.0
AP1M1 6183.0
KPNA5 6135.0
RPL34 6124.0
RPL7 6080.0
POLR2I 6073.0
NUP160 6067.0
SEC24A 6055.0
RPL17 6034.0
H2BC10 6026.0
COMT 6022.0
TAF15 6021.0
PLCG1 5998.0
KPNB1 5988.0
YWHAZ 5941.0
XRCC5 5926.0
PSMD12 5909.0
SNRPG 5906.0
GSK3A 5894.0
MGAT1 5886.0
RPS29 5882.0
NFKB1 5873.0
CHMP7 5849.0
STAM2 5833.0
FEN1 5830.0
HLA-C 5819.0
PRKCSH 5817.0
PSMA3 5797.0
GPC2 5787.0
RAB5A 5740.0
PSMC2 5730.0
SIKE1 5726.0
PSMA1 5699.0
RPS15 5697.0
ST6GALNAC4 5677.0
ARPC4 5654.0
HNRNPK 5648.0
FZD7 5640.0
NOXA1 5625.0
MYH9 5614.0
NMT2 5580.0
ARPC5 5557.0
RANBP2 5556.0
NUP62 5513.0
PSMB4 5511.0
NUP35 5491.0
RPL18A 5467.0
PSMA7 5457.0
NUP107 5390.0
ITGA4 5389.0
PSTPIP1 5373.0
RPL32 5357.0
ATP1A1 5343.0
BECN1 5324.0
EDEM2 5276.0
PRKACA 5275.0
PSMC5 5252.0
SEH1L 5251.0
CRB3 5232.0
CBL 5231.0
RPS15A 5210.0
H3C11 5197.0
VAMP1 5183.0
AP2S1 5163.0
PTK2 5116.0
GTF2E1 5096.0
GNG10 5081.0
RPS10 5051.0
RPS19 5043.0
WASL 5035.0
CLTC 4979.0
HSP90AA1 4971.0
PSMA4 4968.0
CREB1 4963.0
CD9 4959.0
POLR2H 4937.0
CRBN 4903.0
NR3C1 4868.0
CYBA 4856.0
AP2M1 4840.0
CEBPD 4787.0
FXYD6 4780.0
TXN 4768.0
RPL35 4765.0
AP1S3 4728.0
RPS20 4727.0
SUDS3 4716.0
HSP90AB1 4714.0
CHMP3 4700.0
FYN 4672.0
ARPC2 4670.0
NCBP2 4667.0
MAPK14 4661.0
MAP2K7 4584.0
GNGT1 4563.0
GNB2 4545.0
H2AC21 4518.0
GNAI3 4516.0
PTPN6 4502.0
BRK1 4501.0
H2BC15 4475.0
IKBKE 4446.0
ELOC 4336.0
GANAB 4329.0
RAB7A 4324.0
ITCH 4318.0
WIPF1 4310.0
AP1G1 4245.0
TUSC3 4199.0
NUP37 4196.0
PSMD3 4188.0
SNRPE 4155.0
EPS15 4115.0
ANO4 4104.0
ST3GAL3 4100.0
ADCY8 4085.0
CTNNB1 4071.0
DYNC1LI2 4052.0
VPS25 4038.0
GTF2E2 4033.0
ST6GALNAC2 4021.0
BAIAP2 3979.0
TBP 3926.0
EIF2AK2 3925.0
PML 3902.0
EEF1A1 3873.0
HSPA1A 3836.0
TUBB6 3809.0
NELFE 3794.0
YWHAG 3771.0
IFNA8 3736.0
ZDHHC20 3704.0
PCBP2 3688.0
MTA3 3682.0
RPSA 3658.0
NUP54 3624.0
SSRP1 3594.0
HLA-G 3559.0
ARID4A 3543.0
ELOB 3538.0
SV2A 3500.0
NMI 3485.0
NPM1 3477.0
KPNA4 3473.0
AP1S1 3472.0
NUP85 3458.0
SDC1 3420.0
PSMC4 3370.0
VPS18 3365.0
POLR2B 3342.0
NUP50 3335.0
GOLGA7 3259.0
PSMD1 3237.0
RPL26L1 3215.0
ARID4B 3208.0
WIPF3 3190.0
H2BC8 3188.0
ATP6V1H 3174.0
IFNA7 3166.0
RPL8 3119.0
VPS4B 3057.0
H2AC8 3039.0
ENO1 3031.0
MAP1LC3B 2964.0
ADAM17 2945.0
RELA 2935.0
NUP133 2881.0
KPNA2 2875.0
PIK3R4 2871.0
GEMIN6 2822.0
ARPC1A 2775.0
POLR2G 2774.0
PSMD5 2770.0
RPS24 2748.0
DUSP16 2724.0
HMOX1 2653.0
KDM1A 2641.0
RPL30 2631.0
ZDHHC5 2623.0
TUBA1A 2579.0
PARP16 2563.0
RIGI 2552.0
NFKB2 2549.0
CDK7 2530.0
RPL37 2527.0
MASP1 2500.0
RPS16 2475.0
ENTPD5 2456.0
VPS45 2389.0
H4C16 2382.0
GTF2A2 2375.0
GATAD2B 2336.0
RPL11 2329.0
ROCK1 2309.0
RPS27L 2308.0
H3C3 2303.0
SYT2 2294.0
DVL2 2267.0
GSK3B 2248.0
GTF2F2 2212.0
AAAS 2175.0
VPS37C 2156.0
PARP9 2154.0
PSMB10 2137.0
IMPDH1 2100.0
IRF7 2053.0
XRCC4 2042.0
VPS37A 2012.0
RPS23 2004.0
ANO9 1974.0
H2AC13 1943.0
POLR2E 1875.0
TXNRD1 1836.0
TAB1 1806.0
GPC6 1790.0
SAP30L 1779.0
ANO5 1769.0
VPS37B 1751.0
PABPN1 1738.0
PSMB1 1698.0
DAXX 1689.0
ELL 1681.0
ITPR2 1677.0
H2AC16 1647.0
TUFM 1634.0
DYNLL1 1562.0
FKBP4 1540.0
SAP18 1491.0
CLTA 1471.0
CUL5 1452.0
ABI2 1447.0
SEC24D 1421.0
RPL36 1365.0
SH3GL3 1345.0
MAP3K7 1330.0
CHMP4B 1329.0
GNG2 1311.0
H4C2 1279.0
RPS11 1269.0
PSMA8 1258.0
PDPK1 1252.0
PSMD2 1209.0
PPIH 1205.0
KPNA3 1168.0
YWHAE 1143.0
RPS27 1132.0
H4C11 1080.0
TAF13 1052.0
PSMD9 1039.0
JAK3 1035.0
TXNIP 1032.0
RIPK2 982.0
MYO10 915.0
VPS41 858.0
CCNH 840.0
H2BC13 823.0
PDCD6IP 816.0
NOD1 810.0
ERCC2 808.0
PSMD14 794.0
RPLP1 792.0
DOCK2 721.0
IFNGR1 711.0
CHMP4A 698.0
RCC1 663.0
KEAP1 640.0
CPSF4 582.0
SDC4 552.0
UBE2N 540.0
RPL22 440.0
PRKAR1A 436.0
IFNGR2 422.0
PSMD11 411.0
PSMA5 410.0
H2AC12 395.0
TGFB1 382.0
GPC1 381.0
ATP1A3 356.0
MBD3 347.0
RPS14 322.0
SOS1 312.0
GNG12 302.0
WIPF2 294.0
NOXO1 293.0
IFNAR1 279.0
CD79B 254.0
ATP1B1 235.0
GTF2H5 189.0
ST3GAL2 170.0
VPS11 112.0
GNG7 95.0
VAV2 82.0
PHF21A 79.0
RPL24 57.0
NDC1 28.0
PARP14 21.0
HCK 14.0
TRIM25 3.0
TBL1XR1 0.0
CD28 -33.0
NUP155 -40.0
RPL14 -57.0
SLC25A4 -127.0
TAF3 -130.0
PSMB5 -134.0
DYNC1LI1 -141.0
SRPK1 -194.0
GEMIN4 -197.0
PRKAR2A -232.0
ADCY7 -245.0
TUBB3 -261.0
PPIB -303.0
DPEP2 -304.0
H4C6 -340.0
MYO5A -352.0
SNF8 -368.0
DDX5 -377.0
NMT1 -407.0
H2AC11 -408.0
RBBP4 -414.0
IFNAR2 -456.0
TRAF3 -477.0
TUBB1 -568.0
TAF4B -638.0
UBC -640.0
SNRPD1 -647.0
FNTA -654.0
CHD4 -663.0
NELFCD -676.0
ANO3 -679.0
YWHAQ -694.0
GTF2B -706.0
RPN1 -715.0
WASF3 -742.0
GJA1 -748.0
NRP1 -788.0
WASF2 -828.0
EEF2 -830.0
RPS3 -850.0
TRIM27 -921.0
STAM -957.0
PARP8 -971.0
ST6GAL1 -1025.0
EP300 -1043.0
SUZ12 -1050.0
CHD3 -1071.0
GNB3 -1112.0
ADCY3 -1144.0
GGT1 -1152.0
MYH2 -1156.0
PSMD13 -1223.0
GNG5 -1226.0
RPL23A -1287.0
H2BC12 -1288.0
TPR -1291.0
ADCY4 -1292.0
ZDHHC11 -1307.0
IL1R1 -1325.0
VPS4A -1338.0
CCNT1 -1363.0
NUP98 -1370.0
MAPK8 -1449.0
AP2B1 -1462.0
TAF2 -1487.0
NUP42 -1491.0
SUPT5H -1539.0
RPL15 -1589.0
ELOA2 -1620.0
DVL3 -1721.0
GTF2H1 -1760.0
NUP93 -1778.0
TKFC -1785.0
ST3GAL1 -1892.0
RHBDF2 -1897.0
CDC42 -1927.0
RPS9 -1972.0
GPC5 -1984.0
H2BC4 -2033.0
PSIP1 -2035.0
CHMP1A -2041.0
AGRN -2079.0
H3C10 -2100.0
AP1B1 -2103.0
ANTXR1 -2118.0
MTA2 -2122.0
NEDD4L -2142.0
TJP1 -2147.0
MVB12A -2155.0
G3BP2 -2167.0
VAV1 -2191.0
HDAC3 -2207.0
PSME3 -2265.0
WNT5A -2270.0
ATP1B3 -2275.0
PATJ -2288.0
H4C13 -2348.0
NFE2L2 -2368.0
ADCY6 -2449.0
MAP2K3 -2469.0
RAC1 -2540.0
NUP188 -2578.0
SAR1B -2613.0
HSPG2 -2636.0
CYFIP2 -2641.0
MGAT4C -2651.0
ADCY9 -2656.0
PARP4 -2736.0
DYNC1I2 -2769.0
H4C12 -2774.0
SYK -2776.0
SYT1 -2788.0
ZDHHC8 -2793.0
FGR -2872.0
UBA52 -2875.0
CCR5 -2879.0
APP -2885.0
SEC24B -2893.0
TAB2 -2940.0
TSG101 -2954.0
PSMB7 -2995.0
YES1 -3041.0
PSME4 -3042.0
SUMO1 -3074.0
ANO2 -3083.0
BTRC -3111.0
VTA1 -3125.0
FUT8 -3147.0
CDH1 -3204.0
PRKAR1B -3239.0
PLCG2 -3244.0
NCBP1 -3261.0
H4C9 -3283.0
GALNT1 -3298.0
NCK1 -3321.0
BANF1 -3329.0
PALS1 -3365.0
H2AC6 -3373.0
BCL2L1 -3377.0
PACS1 -3393.0
IFNA1 -3395.0
KPNA1 -3430.0
VPS33A -3438.0
MNAT1 -3468.0
SRC -3509.0
NUP205 -3512.0
TBK1 -3532.0
ADCY1 -3559.0
EZH2 -3560.0
VPS39 -3592.0
RPS7 -3608.0
UVRAG -3633.0
AHCYL1 -3674.0
EED -3682.0
GRB2 -3685.0
CYSLTR2 -3718.0
NCOR1 -3721.0
NCKAP1L -3726.0
VCP -3748.0
RUNX1 -3762.0
AP2A2 -3809.0
CHMP2A -3819.0
ELMO2 -3825.0
SNRPB -3828.0
CALM1 -3834.0
SNAP25 -3838.0
POLR2F -3844.0
ATG14 -3886.0
PSMA6 -3897.0
FXYD1 -3906.0
SFN -3911.0
GNB4 -3930.0
VPS28 -3955.0
PTGES3 -3960.0
STAT1 -3961.0
HBEGF -3983.0
VEGFA -3998.0
GNAI2 -4054.0
GTF2H4 -4059.0
NLRP3 -4141.0
IL6R -4160.0
IL10 -4177.0
ANO10 -4181.0
GEMIN5 -4203.0
EGFR -4211.0
MET -4214.0
TMPRSS2 -4241.0
PSMB2 -4270.0
LYN -4281.0
CCNT2 -4284.0
HGS -4314.0
TLR1 -4357.0
LIG1 -4363.0
IFNA13 -4381.0
POLR2L -4399.0
MAP2K1 -4447.0
PAK2 -4482.0
FKBP1A -4508.0
TUBA8 -4516.0
RPL3L -4519.0
STT3A -4550.0
UBAP1 -4551.0
ZDHHC2 -4577.0
HAVCR1 -4581.0
TUBA1C -4583.0
RNF135 -4592.0
GPS2 -4594.0
NUP210 -4632.0
H4C5 -4637.0
MASP2 -4650.0
C3 -4675.0
TLR2 -4705.0
TYK2 -4707.0
MAN2A1 -4762.0
RPL29 -4767.0
NCKIPSD -4774.0
SEM1 -4777.0
SEC13 -4820.0
CCNK -4838.0
ABL1 -4874.0
H4C4 -4917.0
TAF4 -4971.0
MAP2K6 -4983.0
TAF7 -5022.0
PSMD8 -5041.0
RCOR1 -5085.0
CTSG -5106.0
CANX -5159.0
FNTB -5167.0
IPO5 -5271.0
MAP2K4 -5319.0
ACTR2 -5323.0
SRPK2 -5370.0
GNG4 -5372.0
P2RX7 -5399.0
ARPC1B -5416.0
TRIM4 -5419.0
LARP1 -5432.0
MYO9B -5443.0
ELMO1 -5461.0
PSMF1 -5472.0
GNG13 -5549.0
GNAI1 -5563.0
STAT2 -5564.0
RPL37A -5673.0
C3AR1 -5692.0
TUBB2A -5696.0
PPIG -5700.0
DOCK1 -5731.0
IKBKB -5768.0
RPL7A -5783.0
H2BC11 -5816.0
SEC24C -5860.0
RIPK1 -5927.0
ITPR1 -5946.0
PSMD6 -5971.0
PIK3C3 -5979.0
NUP43 -6011.0
CTNND1 -6017.0
RANBP1 -6019.0
RNGTT -6046.0
IL18 -6126.0
ANO1 -6202.0
ARF1 -6210.0
ANO6 -6266.0
PRMT1 -6289.0
RPL22L1 -6323.0
GNB5 -6344.0
GGT5 -6353.0
H2AC25 -6359.0
DYNC1H1 -6369.0
ELOA -6416.0
DNAJC3 -6423.0
VAV3 -6446.0
CD163 -6482.0
ZDHHC3 -6535.0
GTF2A1 -6537.0
CDK9 -6583.0
POM121 -6621.0
AKT1 -6634.0
NELFB -6659.0
H2BC26 -6669.0
ENTPD1 -6724.0
MAPK1 -6741.0
SH3GL1 -6751.0
CBLL1 -6811.0
FCGR3A -6820.0
ITGB1 -6845.0
MAN1B1 -6855.0
NCOR2 -6856.0
PSMB6 -6874.0
RPL26 -6909.0
ZBP1 -6913.0
MAP2K2 -6985.0
PRKAR2B -7133.0
ROCK2 -7167.0
IL1B -7175.0
CREBBP -7206.0
RAE1 -7253.0
POLR2J -7312.0
ANO7 -7319.0
H2AC1 -7358.0
SMAD3 -7379.0
CALR -7434.0
NELFA -7439.0
DPEP1 -7442.0
MAPK3 -7453.0
GNG3 -7479.0
ATP1A4 -7487.0
JAK1 -7504.0
SFTPD -7542.0
POLR2A -7563.0
IL17RA -7576.0
H2BC1 -7617.0
POM121C -7658.0
DVL1 -7756.0
MVB12B -7773.0
DYNC1I1 -7779.0
ST6GALNAC3 -7800.0
TRAF6 -7812.0
PLK2 -7841.0
CHUK -7843.0
DPEP3 -7909.0
ANTXR2 -8000.0
AKT2 -8044.0
AP2A1 -8051.0
AKT3 -8134.0
ADCY2 -8183.0
CUL3 -8184.0
PSME1 -8232.0
GNB1 -8243.0
ST3GAL4 -8336.0
RNF213 -8340.0
UBE2I -8350.0
IL17A -8377.0
CASP1 -8384.0
IFNB1 -8500.0
MTA1 -8549.0
ADORA2B -8569.0
JAK2 -8612.0
CTDP1 -8635.0
MOGS -8647.0
PARP6 -8659.0
RPL31 -8668.0
GATAD2A -8692.0
CRK -8737.0
FCGR2A -8750.0
CHMP4C -8782.0
TAF5 -8856.0
CHMP6 -8868.0
GNG11 -8944.0
DDOST -8965.0
ADCY5 -9093.0
PSMB11 -9151.0
P2RX4 -9172.0
VPS16 -9188.0
ATP1A2 -9203.0
GNAZ -9209.0
STING1 -9367.0
FXYD4 -9372.0
GNAT3 -9408.0
RANGAP1 -9421.0
IL17F -9486.0
ITPR3 -9567.0
ERCC3 -9580.0
TUBA3C -9626.0
IFNA6 -9678.0
MGAT4B -9679.0
CYFIP1 -9697.0
IMPDH2 -9705.0
BRMS1 -9811.0
IFNA2 -9860.0
NOD2 -9869.0
BST2 -9892.0
NOS2 -9912.0
CD4 -9990.0
TUBAL3 -9995.0
APOBEC3G -10067.0
MBL2 -10070.0
CTSL -10161.0
PRKACG -10206.0
TAF1L -10328.0
FURIN -10395.0
IFNA14 -10645.0
TUBA3D -10657.0
RPL10L -10702.0
BRD4 -10902.0
TUBA3E -11051.0



REACTOME_NONSENSE_MEDIATED_DECAY_NMD

REACTOME_NONSENSE_MEDIATED_DECAY_NMD
1443
set REACTOME_NONSENSE_MEDIATED_DECAY_NMD
setSize 107
pANOVA 2.44e-09
s.dist 0.334
p.adjustANOVA 4.42e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS5 10401
SMG1 10380
RPL39L 10015
RPS13 10010
RPLP0 9720
RPL27 9406
RPL6 9269
RBM8A 9140
RPL27A 8979
RPS28 8978
RPS8 8920
RPS12 8794
RPS25 8638
RPL19 8597
RPL9 8592
RPL12 8542
RPS6 8501
RPL41 8240
RPL18 8234
RPL10A 8175

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS5 10401.0
SMG1 10380.0
RPL39L 10015.0
RPS13 10010.0
RPLP0 9720.0
RPL27 9406.0
RPL6 9269.0
RBM8A 9140.0
RPL27A 8979.0
RPS28 8978.0
RPS8 8920.0
RPS12 8794.0
RPS25 8638.0
RPL19 8597.0
RPL9 8592.0
RPL12 8542.0
RPS6 8501.0
RPL41 8240.0
RPL18 8234.0
RPL10A 8175.0
RPS2 8109.0
FAU 8086.0
RPL5 8055.0
RPL36AL 8033.5
RPS3A 7941.0
RPL23 7907.0
RPS18 7868.0
RPL13 7712.0
RPS27A 7698.0
RPL13A 7489.5
RPLP2 7348.0
RPL3 7194.0
RPL4 7148.0
PPP2R1A 6985.0
RPS26 6957.0
RPL38 6914.0
RPS21 6901.0
RPL35A 6893.0
RPL21 6804.0
RPL28 6441.0
RPL34 6124.0
RPL7 6080.0
RPL17 6034.0
RPS29 5882.0
RPS15 5697.0
RPL18A 5467.0
PNRC2 5441.0
RPL32 5357.0
RPS15A 5210.0
RPS10 5051.0
RPS19 5043.0
SMG9 5001.0
SMG6 4923.0
RPL35 4765.0
RPS20 4727.0
NCBP2 4667.0
GSPT1 4602.0
RPSA 3658.0
UPF3A 3657.0
UPF2 3441.0
RPL26L1 3215.0
RPL8 3119.0
RPS24 2748.0
RPL30 2631.0
RPL37 2527.0
RPS16 2475.0
MAGOHB 2447.0
RPL11 2329.0
RPS27L 2308.0
RPS23 2004.0
SMG5 1946.0
RPL36 1365.0
MAGOH 1349.0
RPS11 1269.0
RPS27 1132.0
UPF1 997.0
RPLP1 792.0
SMG8 757.0
SMG7 692.0
ETF1 594.0
RPL22 440.0
RPS14 322.0
RPL24 57.0
RPL14 -57.0
PPP2CA -89.0
DCP1A -92.0
RPS3 -850.0
EIF4A3 -993.0
PPP2R2A -1010.0
RPL23A -1287.0
RPL15 -1589.0
RPS9 -1972.0
EIF4G1 -2605.0
UBA52 -2875.0
NCBP1 -3261.0
RPS7 -3608.0
RPL3L -4519.0
RPL29 -4767.0
RPL37A -5673.0
RPL7A -5783.0
PABPC1 -5994.0
RPL22L1 -6323.0
RNPS1 -6758.0
RPL26 -6909.0
CASC3 -7100.0
RPL31 -8668.0
RPL10L -10702.0



REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION

REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION
151
set REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION
setSize 87
pANOVA 2.69e-09
s.dist 0.369
p.adjustANOVA 4.42e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS5 10401
RPL39L 10015
RPS13 10010
RPLP0 9720
RPL27 9406
RPL6 9269
RPL27A 8979
RPS28 8978
RPS8 8920
RPS12 8794
RPS25 8638
RPL19 8597
RPL9 8592
RPL12 8542
RPS6 8501
RPL41 8240
RPL18 8234
RPL10A 8175
RPS2 8109
FAU 8086

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS5 10401.0
RPL39L 10015.0
RPS13 10010.0
RPLP0 9720.0
RPL27 9406.0
RPL6 9269.0
RPL27A 8979.0
RPS28 8978.0
RPS8 8920.0
RPS12 8794.0
RPS25 8638.0
RPL19 8597.0
RPL9 8592.0
RPL12 8542.0
RPS6 8501.0
RPL41 8240.0
RPL18 8234.0
RPL10A 8175.0
RPS2 8109.0
FAU 8086.0
RPL5 8055.0
RPL36AL 8033.5
RPS3A 7941.0
RPL23 7907.0
RPS18 7868.0
RPL13 7712.0
RPS27A 7698.0
RPL13A 7489.5
RPLP2 7348.0
RPL3 7194.0
RPL4 7148.0
EEF1G 7050.0
RPS26 6957.0
RPL38 6914.0
RPS21 6901.0
RPL35A 6893.0
RPL21 6804.0
RPL28 6441.0
RPL34 6124.0
RPL7 6080.0
RPL17 6034.0
RPS29 5882.0
RPS15 5697.0
RPL18A 5467.0
RPL32 5357.0
RPS15A 5210.0
RPS10 5051.0
RPS19 5043.0
RPL35 4765.0
RPS20 4727.0
EEF1A1 3873.0
RPSA 3658.0
RPL26L1 3215.0
RPL8 3119.0
RPS24 2748.0
RPL30 2631.0
RPL37 2527.0
RPS16 2475.0
RPL11 2329.0
RPS27L 2308.0
RPS23 2004.0
RPL36 1365.0
RPS11 1269.0
RPS27 1132.0
RPLP1 792.0
EEF1A2 537.0
RPL22 440.0
RPS14 322.0
RPL24 57.0
RPL14 -57.0
EEF2 -830.0
RPS3 -850.0
RPL23A -1287.0
RPL15 -1589.0
RPS9 -1972.0
EEF1B2 -2867.0
UBA52 -2875.0
RPS7 -3608.0
RPL3L -4519.0
RPL29 -4767.0
EEF1D -4848.0
RPL37A -5673.0
RPL7A -5783.0
RPL22L1 -6323.0
RPL26 -6909.0
RPL31 -8668.0
RPL10L -10702.0



REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS

REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS
1364
set REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS
setSize 161
pANOVA 3.93e-09
s.dist 0.269
p.adjustANOVA 5.45e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS5 10401
LDB1 10030
RPL39L 10015
RPS13 10010
PSMB8 9883
RPLP0 9720
HOXA2 9480
PSMC1 9440
RPL27 9406
RPL6 9269
RBM8A 9140
RPL27A 8979
RPS28 8978
RPS8 8920
RBX1 8801
RPS12 8794
RPS25 8638
PSMD4 8637
RPL19 8597
RPL9 8592

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS5 10401.0
LDB1 10030.0
RPL39L 10015.0
RPS13 10010.0
PSMB8 9883.0
RPLP0 9720.0
HOXA2 9480.0
PSMC1 9440.0
RPL27 9406.0
RPL6 9269.0
RBM8A 9140.0
RPL27A 8979.0
RPS28 8978.0
RPS8 8920.0
RBX1 8801.0
RPS12 8794.0
RPS25 8638.0
PSMD4 8637.0
RPL19 8597.0
RPL9 8592.0
PSME2 8563.0
RPL12 8542.0
RPS6 8501.0
LHX9 8452.0
PSMD7 8416.0
PSMB3 8251.0
RPL41 8240.0
RPL18 8234.0
RPL10A 8175.0
LHX2 8124.0
RPS2 8109.0
FAU 8086.0
RPL5 8055.0
RPL36AL 8033.5
RPS3A 7941.0
RPL23 7907.0
PSMC6 7899.0
RPS18 7868.0
RPL13 7712.0
RPS27A 7698.0
RPL13A 7489.5
RPLP2 7348.0
UBB 7319.0
RPL3 7194.0
RPL4 7148.0
PSMC3 7021.0
RPS26 6957.0
RPL38 6914.0
RPS21 6901.0
RPL35A 6893.0
PSMB9 6881.0
RPL21 6804.0
PSMA2 6802.0
RPL28 6441.0
USP33 6240.0
RPL34 6124.0
RPL7 6080.0
RPL17 6034.0
PSMD12 5909.0
RPS29 5882.0
PSMA3 5797.0
PSMC2 5730.0
PSMA1 5699.0
RPS15 5697.0
LHX4 5566.0
PSMB4 5511.0
RPL18A 5467.0
PSMA7 5457.0
RPL32 5357.0
PSMC5 5252.0
RPS15A 5210.0
RPS10 5051.0
RPS19 5043.0
PSMA4 4968.0
RPL35 4765.0
RPS20 4727.0
NCBP2 4667.0
GSPT1 4602.0
ELOC 4336.0
PSMD3 4188.0
RPSA 3658.0
UPF3A 3657.0
ELOB 3538.0
UPF2 3441.0
PSMC4 3370.0
PSMD1 3237.0
RPL26L1 3215.0
RPL8 3119.0
PSMD5 2770.0
RPS24 2748.0
RPL30 2631.0
RPL37 2527.0
RPS16 2475.0
MAGOHB 2447.0
RPL11 2329.0
RPS27L 2308.0
PSMB10 2137.0
RPS23 2004.0
PSMB1 1698.0
RPL36 1365.0
MAGOH 1349.0
RPS11 1269.0
PSMA8 1258.0
PSMD2 1209.0
RPS27 1132.0
PSMD9 1039.0
PSMD14 794.0
RPLP1 792.0
ETF1 594.0
MSI1 533.0
RPL22 440.0
PSMD11 411.0
PSMA5 410.0
RPS14 322.0
RPL24 57.0
ROBO3 -12.0
RPL14 -57.0
PSMB5 -134.0
UBC -640.0
RPS3 -850.0
EIF4A3 -993.0
PSMD13 -1223.0
RPL23A -1287.0
CUL2 -1490.0
RPL15 -1589.0
RPS9 -1972.0
PSME3 -2265.0
EIF4G1 -2605.0
ISL1 -2615.0
UBA52 -2875.0
PSMB7 -2995.0
PSME4 -3042.0
NCBP1 -3261.0
RPS7 -3608.0
ZSWIM8 -3783.0
PSMA6 -3897.0
PSMB2 -4270.0
RPL3L -4519.0
RPL29 -4767.0
SEM1 -4777.0
LHX3 -4931.0
PSMD8 -5041.0
PSMF1 -5472.0
RPL37A -5673.0
SLIT2 -5703.0
RPL7A -5783.0
PSMD6 -5971.0
PABPC1 -5994.0
ROBO1 -6102.0
SLIT1 -6188.0
RPL22L1 -6323.0
RNPS1 -6758.0
PSMB6 -6874.0
RPL26 -6909.0
CASC3 -7100.0
DAG1 -7956.0
PSME1 -8232.0
RPL31 -8668.0
ROBO2 -8739.0
PSMB11 -9151.0
RPL10L -10702.0



REACTOME_CELL_CYCLE_MITOTIC

REACTOME_CELL_CYCLE_MITOTIC
1112
set REACTOME_CELL_CYCLE_MITOTIC
setSize 539
pANOVA 3.98e-09
s.dist 0.148
p.adjustANOVA 5.45e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C12 10715
MZT2B 10707
TUBB8 10699
H2BC14 10635
H2AC14 10619
TUBB4B 10590
MZT2A 10501
H2BC6 10447
H2BC17 10375
DYNLL2 10298
H4C1 10268
H2AC4 10244
SET 10185
H3C1 10183
H3C6 9987
MAPRE1 9923
KIF2A 9896
PSMB8 9883
KNL1 9842
HAUS8 9829

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C12 10715.0
MZT2B 10707.0
TUBB8 10699.0
H2BC14 10635.0
H2AC14 10619.0
TUBB4B 10590.0
MZT2A 10501.0
H2BC6 10447.0
H2BC17 10375.0
DYNLL2 10298.0
H4C1 10268.0
H2AC4 10244.0
SET 10185.0
H3C1 10183.0
H3C6 9987.0
MAPRE1 9923.0
KIF2A 9896.0
PSMB8 9883.0
KNL1 9842.0
HAUS8 9829.0
TUBG2 9780.0
UBE2S 9716.0
HAUS1 9712.0
CDK11A 9610.0
H3C2 9609.0
CDC25B 9568.0
CDK4 9521.0
PSMC1 9440.0
MAD2L1 9381.0
CSNK2A1 9373.0
H3C8 9237.0
H2AJ 9219.0
CDC26 9208.0
NDEL1 8967.0
CDKN2B 8957.0
H4C3 8934.0
CEP70 8931.0
RBX1 8801.0
TUBB 8793.0
RBL2 8791.0
H4C8 8774.0
H2AC20 8751.0
POLE3 8715.0
ZWINT 8650.0
PSMD4 8637.0
NEK6 8585.0
CTDNEP1 8574.0
TUBA4B 8566.0
PSME2 8563.0
CKS1B 8493.0
CENPM 8454.0
PSMD7 8416.0
SKP1 8408.0
TUBB2B 8395.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0
NEDD1 8330.0
POLD4 8324.0
TP53 8272.0
TUBA4A 8265.0
PSMB3 8251.0
TUBG1 8218.0
KIF23 8212.0
SIRT2 8159.0
PCNA 8157.0
PRIM1 8152.0
MCM5 8147.0
ORC6 8118.0
NUP153 8090.0
NSL1 8084.0
LIN37 8022.0
H2BC9 7978.5
H3C7 7978.5
SPC24 7943.0
EML4 7914.0
NUP58 7912.0
PSMC6 7899.0
DHFR 7884.0
RB1 7836.0
H2BC21 7828.0
TYMS 7778.0
ANAPC11 7732.0
BLZF1 7723.0
RPS27A 7698.0
XPO1 7679.0
MYC 7649.0
AJUBA 7627.0
CENPE 7598.0
H2AC18 7550.5
H2AC19 7550.5
CDC25C 7483.0
GTSE1 7452.0
PLK1 7394.0
CDK1 7383.0
RAB1A 7357.0
E2F5 7351.0
RBL1 7321.0
UBB 7319.0
H3C4 7298.0
CENPA 7291.0
HAUS2 7249.0
TUBA1B 7189.0
E2F1 7180.0
PAFAH1B1 7087.0
ORC4 7082.0
PSMC3 7021.0
SKP2 7007.0
TUBB4A 7002.0
PPP2R1A 6985.0
CEP135 6981.0
ACTR1A 6970.0
PSMB9 6881.0
MASTL 6854.0
NUMA1 6844.0
H2BC3 6830.0
RAN 6824.0
PSMA2 6802.0
HDAC1 6791.0
TPX2 6742.0
CHMP2B 6689.0
PDS5A 6676.0
CDC16 6674.0
MCM3 6656.0
H2BC5 6618.0
CDKN2D 6595.0
LPIN2 6562.0
CEP57 6518.0
H2AZ2 6467.0
NDC80 6455.0
AURKB 6374.0
HAUS4 6371.0
ANAPC16 6333.0
PCM1 6298.0
NUP214 6207.0
NUP88 6185.0
GINS4 6164.0
NUP160 6067.0
H2BC10 6026.0
KPNB1 5988.0
AURKA 5943.0
SPC25 5934.0
PSMD12 5909.0
DNA2 5890.0
CHMP7 5849.0
ALMS1 5848.0
FEN1 5830.0
PSMA3 5797.0
PSMC2 5730.0
MIS12 5708.0
PSMA1 5699.0
SKA1 5694.0
RAB1B 5659.0
HMMR 5605.0
PMF1 5583.0
FBXO5 5571.0
RANBP2 5556.0
NUP62 5513.0
PSMB4 5511.0
NUP35 5491.0
CENPK 5486.0
CCND1 5472.0
PSMA7 5457.0
POLA2 5403.0
NUP107 5390.0
PRKACA 5275.0
PSMC5 5252.0
SEH1L 5251.0
CNEP1R1 5217.0
H3C11 5197.0
PPP2R5A 5135.0
CDC20 5122.0
PHLDA1 5067.0
POLE2 5028.0
HSP90AA1 4971.0
PSMA4 4968.0
CEP152 4952.0
GINS2 4947.0
KIF18A 4930.0
ENSA 4929.0
GINS1 4852.0
VRK2 4791.0
RFC5 4755.0
NEK2 4725.0
HSP90AB1 4714.0
CHMP3 4700.0
LPIN3 4666.0
AKAP9 4591.0
NCAPD2 4587.0
BUB1B 4566.0
ORC2 4544.0
E2F2 4524.0
PTK6 4508.0
H2BC15 4475.0
SKA2 4335.0
ORC1 4331.0
PPP2R5B 4283.0
TOP2A 4243.0
NUP37 4196.0
PSMD3 4188.0
CSNK2A2 4101.0
ARPP19 4058.0
DYNC1LI2 4052.0
WEE1 4032.0
CEP43 3999.0
RFC4 3986.0
FKBPL 3939.0
SGO1 3934.0
CDC23 3912.0
CDC6 3859.0
CENPL 3837.0
ANAPC10 3818.0
TUBB6 3809.0
YWHAG 3771.0
CEP250 3700.0
NUP54 3624.0
MCM2 3608.0
TNPO1 3598.0
CDK2 3557.0
NUP85 3458.0
PSMC4 3370.0
RPA3 3368.0
USO1 3354.0
NUP50 3335.0
TAOK1 3289.0
RAB2A 3281.0
PTTG1 3278.0
DSN1 3269.0
PSMD1 3237.0
GORASP2 3216.0
H2BC8 3188.0
KIF20A 3180.0
NUF2 3136.0
CENPT 3121.0
CDCA8 3106.0
CENPC 3064.0
H2AC8 3039.0
CCND3 3034.0
PPP2R5E 3022.0
MCM6 2968.0
CDKN2A 2953.0
RAB8A 2943.0
MZT1 2913.0
E2F3 2886.0
NUP133 2881.0
ANAPC4 2868.0
PPP2R5D 2818.0
BORA 2809.0
PSMD5 2770.0
FOXM1 2757.0
E2F4 2753.0
B9D2 2744.0
ANAPC1 2721.0
CENPS 2624.0
CDKN1C 2618.0
TUBA1A 2579.0
CDK7 2530.0
CSNK2B 2449.0
H4C16 2382.0
SPDL1 2374.0
H3C3 2303.0
HAUS5 2273.0
GSK3B 2248.0
AAAS 2175.0
KNTC1 2148.0
PSMB10 2137.0
CCNB2 2044.0
ESCO1 2007.0
PDS5B 1874.0
FBXL18 1781.0
DBF4 1773.0
PSMB1 1698.0
DYNLL1 1562.0
RPA2 1446.0
CHMP4B 1329.0
H4C2 1279.0
CDC14A 1278.0
PSMA8 1258.0
CEP63 1246.0
PPP2CB 1242.0
PSMD2 1209.0
CCND2 1203.0
ANKLE2 1152.0
YWHAE 1143.0
RPS27 1132.0
LEMD3 1122.0
H4C11 1080.0
PSMD9 1039.0
PRIM2 961.0
MCM4 954.0
CENPH 938.0
MYBL2 856.0
CEP41 851.0
CEP192 843.0
CCNH 840.0
H2BC13 823.0
PSMD14 794.0
TUBGCP3 773.0
NEK9 771.0
MCM8 737.0
CHMP4A 698.0
CCNE2 668.0
RCC1 663.0
ZW10 644.0
PLK4 535.0
CENPO 442.0
CLASP2 412.0
PSMD11 411.0
PSMA5 410.0
HAUS3 272.0
CCP110 260.0
ZWILCH 197.0
PPP1R12A 114.0
NUDC 91.0
CDC27 89.0
ANAPC7 43.0
NDC1 28.0
NUP155 -40.0
PPP2CA -89.0
PPP1CB -118.0
PSMB5 -134.0
DYNC1LI1 -141.0
CDKN2C -189.0
TUBB3 -261.0
CENPN -305.0
UBE2E1 -331.0
H4C6 -340.0
CDK11B -347.0
RBBP4 -414.0
ODF2 -460.0
NCAPD3 -467.0
CDKN1B -509.0
TFDP2 -533.0
WAPL -534.0
NDE1 -565.0
TUBB1 -568.0
CCNB1 -600.0
BUB1 -631.0
UBC -640.0
SPAST -691.0
NEK7 -729.0
POLD1 -744.0
CDKN1A -800.0
TUBGCP4 -808.0
CCNE1 -881.0
CCNA1 -892.0
AHCTF1 -1001.0
PPP2R2A -1010.0
EP300 -1043.0
CEP290 -1045.0
FBXW11 -1172.0
PSMD13 -1223.0
VRK1 -1255.0
LBR -1269.0
H2BC12 -1288.0
TPR -1291.0
MCM10 -1298.0
PPP2R5C -1316.0
VPS4A -1338.0
NUP98 -1370.0
SMC4 -1405.0
NUP42 -1491.0
BUB3 -1503.0
H2AZ1 -1561.0
FBXL7 -1639.0
CDC7 -1658.0
CDC45 -1753.0
CENPQ -1771.0
PPP1CC -1773.0
NUP93 -1778.0
PCNT -1854.0
PRKCB -1916.0
POLE -2012.0
GINS3 -2028.0
H2BC4 -2033.0
CDK6 -2037.0
IST1 -2089.0
H3C10 -2100.0
DCTN1 -2108.0
RFC3 -2132.0
CDK5RAP2 -2164.0
GMNN -2214.0
PSME3 -2265.0
GORASP1 -2269.0
RPA1 -2286.0
H4C13 -2348.0
STAG1 -2377.0
CEP164 -2410.0
RCC2 -2441.0
CKAP5 -2537.0
NUP188 -2578.0
CENPP -2623.0
NME7 -2681.0
CUL1 -2716.0
KIF2C -2754.0
NCAPG -2760.0
DYNC1I2 -2769.0
H4C12 -2774.0
UBE2C -2846.0
UBA52 -2875.0
PSMB7 -2995.0
NIPBL -3006.0
RFC2 -3028.0
SMC2 -3038.0
PSME4 -3042.0
NINL -3062.0
CEP76 -3070.0
SUMO1 -3074.0
BTRC -3111.0
CDCA5 -3126.0
ANAPC5 -3127.0
KMT5A -3229.0
H4C9 -3283.0
NCAPG2 -3295.0
BANF1 -3329.0
H2AC6 -3373.0
PRKCA -3379.0
CEP78 -3450.0
LIN52 -3460.0
MNAT1 -3468.0
SFI1 -3491.0
CDT1 -3492.0
SRC -3509.0
NUP205 -3512.0
INCENP -3590.0
CCNA2 -3622.0
RRM2 -3706.0
CC2D1B -3711.0
ITGB3BP -3785.0
CHMP2A -3819.0
CDC25A -3836.0
PSMA6 -3897.0
PPP1R12B -3915.0
CLASP1 -3976.0
OPTN -4164.0
PSMB2 -4270.0
LYN -4281.0
LIG1 -4363.0
CENPF -4488.0
LPIN1 -4510.0
TUBA8 -4516.0
LIN54 -4537.0
SSNA1 -4575.0
TUBA1C -4583.0
NUP210 -4632.0
H4C5 -4637.0
SGO2 -4765.0
SEM1 -4777.0
SEC13 -4820.0
ABL1 -4874.0
H4C4 -4917.0
POLD2 -4947.0
ORC3 -4974.0
NCAPH -5011.0
PSMD8 -5041.0
H2AX -5114.0
DCTN3 -5120.0
RAD21 -5203.0
ANAPC15 -5225.0
PPME1 -5259.0
HAUS6 -5265.0
CABLES1 -5348.0
TMPO -5365.0
PSMF1 -5472.0
SDCCAG8 -5620.0
POLD3 -5644.0
TUBB2A -5696.0
MAD1L1 -5791.0
H2BC11 -5816.0
SMC3 -5831.0
LEMD2 -5864.0
NCAPH2 -5925.0
LMNB1 -5936.0
PSMD6 -5971.0
NUP43 -6011.0
TUBGCP5 -6056.0
LCMT1 -6073.0
TUBGCP6 -6161.0
MCM7 -6234.0
CENPU -6237.0
DYNC1H1 -6369.0
MAX -6513.0
GOLGA2 -6534.0
E2F6 -6574.0
TFDP1 -6580.0
POM121 -6621.0
AKT1 -6634.0
H2BC26 -6669.0
CEP131 -6715.0
LMNA -6719.0
MAPK1 -6741.0
H3-4 -6761.0
PSMB6 -6874.0
ORC5 -6898.0
CLIP1 -7030.0
CEP72 -7082.0
MCPH1 -7094.0
PRKAR2B -7133.0
TK1 -7156.0
UBE2D1 -7157.0
RAE1 -7253.0
FZR1 -7345.0
ESCO2 -7391.0
MAPK3 -7453.0
TUBGCP2 -7550.0
PKMYT1 -7590.0
H2BC1 -7617.0
LIN9 -7623.0
POM121C -7658.0
CENPJ -7669.0
DYNC1I1 -7779.0
PPP2R2D -7813.0
CSNK1D -8034.0
AKT2 -8044.0
CNTRL -8064.0
AKT3 -8134.0
PSME1 -8232.0
UBE2I -8350.0
MAU2 -8421.0
DCTN2 -8430.0
RFC1 -8464.0
PPP2R1B -8545.0
JAK2 -8612.0
BIRC5 -8677.0
CHMP4C -8782.0
CHMP6 -8868.0
PSMB11 -9151.0
RANGAP1 -9421.0
DYRK1A -9464.0
ANAPC2 -9497.0
TUBA3C -9626.0
POLE4 -9664.0
ESPL1 -9689.0
CSNK1E -9776.0
TUBAL3 -9995.0
KIF2B -10643.0
TUBA3D -10657.0
TUBA3E -11051.0



REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE

REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE
271
set REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE
setSize 105
pANOVA 7.43e-09
s.dist 0.326
p.adjustANOVA 9.38e-07



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS5 10401
RPL39L 10015
RPS13 10010
SRP54 9793
RPLP0 9720
SEC61B 9705
RPL27 9406
RPL6 9269
RPL27A 8979
RPS28 8978
RPS8 8920
RPS12 8794
TRAM1 8753
RPS25 8638
RPL19 8597
RPL9 8592
RPL12 8542
RPS6 8501
RPL41 8240
RPL18 8234

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS5 10401.0
RPL39L 10015.0
RPS13 10010.0
SRP54 9793.0
RPLP0 9720.0
SEC61B 9705.0
RPL27 9406.0
RPL6 9269.0
RPL27A 8979.0
RPS28 8978.0
RPS8 8920.0
RPS12 8794.0
TRAM1 8753.0
RPS25 8638.0
RPL19 8597.0
RPL9 8592.0
RPL12 8542.0
RPS6 8501.0
RPL41 8240.0
RPL18 8234.0
RPL10A 8175.0
RPS2 8109.0
FAU 8086.0
RPL5 8055.0
RPL36AL 8033.5
RPS3A 7941.0
RPL23 7907.0
RPS18 7868.0
RPL13 7712.0
RPS27A 7698.0
RPN2 7689.0
RPL13A 7489.5
RPLP2 7348.0
RPL3 7194.0
RPL4 7148.0
RPS26 6957.0
RPL38 6914.0
RPS21 6901.0
RPL35A 6893.0
RPL21 6804.0
RPL28 6441.0
SRP14 6335.0
RPL34 6124.0
RPL7 6080.0
RPL17 6034.0
RPS29 5882.0
RPS15 5697.0
RPL18A 5467.0
RPL32 5357.0
RPS15A 5210.0
RPS10 5051.0
RPS19 5043.0
RPL35 4765.0
RPS20 4727.0
SEC61G 4095.0
SPCS1 4026.0
RPSA 3658.0
SRP19 3248.0
RPL26L1 3215.0
RPL8 3119.0
SEC11A 2763.0
RPS24 2748.0
RPL30 2631.0
RPL37 2527.0
RPS16 2475.0
SEC11C 2368.0
RPL11 2329.0
RPS27L 2308.0
SRP72 2092.0
RPS23 2004.0
SSR3 1859.0
RPL36 1365.0
SSR2 1333.0
RPS11 1269.0
RPS27 1132.0
RPLP1 792.0
RPL22 440.0
RPS14 322.0
RPL24 57.0
RPL14 -57.0
RPN1 -715.0
RPS3 -850.0
SRPRA -926.0
SPCS3 -1120.0
SPCS2 -1190.0
RPL23A -1287.0
RPL15 -1589.0
RPS9 -1972.0
SRPRB -2045.0
SRP68 -2347.0
UBA52 -2875.0
SRP9 -3037.0
RPS7 -3608.0
RPL3L -4519.0
RPL29 -4767.0
SEC61A2 -5510.0
RPL37A -5673.0
RPL7A -5783.0
RPL22L1 -6323.0
RPL26 -6909.0
SEC61A1 -7180.0
SSR1 -7224.0
RPL31 -8668.0
DDOST -8965.0
RPL10L -10702.0



REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION
1161
set REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION
setSize 1336
pANOVA 9.83e-09
s.dist 0.0934
p.adjustANOVA 1.15e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
ZNF595 10835
RETN 10761
ZNF676 10758
ZNF320 10730
H3C12 10715
ZNF860 10661
H2BC14 10635
H2AC14 10619
RGCC 10486
FASLG 10485
ZNF473 10484
H2BC6 10447
PLK3 10442
ZNF627 10402
TCF7 10383
GEM 10381
H2BC17 10375
ZNF718 10305
ZNF717 10283
H4C1 10268

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ZNF595 10835.0
RETN 10761.0
ZNF676 10758.0
ZNF320 10730.0
H3C12 10715.0
ZNF860 10661.0
H2BC14 10635.0
H2AC14 10619.0
RGCC 10486.0
FASLG 10485.0
ZNF473 10484.0
H2BC6 10447.0
PLK3 10442.0
ZNF627 10402.0
TCF7 10383.0
GEM 10381.0
H2BC17 10375.0
ZNF718 10305.0
ZNF717 10283.0
H4C1 10268.0
ZNF354A 10250.0
H2AC4 10244.0
LEF1 10209.0
COX14 10198.0
ZNF786 10188.0
H3C1 10183.0
LAMTOR5 10174.0
ZNF17 10150.0
ZNF70 10127.0
TGIF2 10119.0
PMAIP1 10118.0
NPPA 10048.0
TAF10 10038.0
LDB1 10030.0
ZNF519 9998.0
H3C6 9987.0
ZKSCAN4 9956.0
ZNF233 9887.0
PSMB8 9883.0
DPY30 9873.0
JUNB 9863.0
CTSV 9850.0
SKIC8 9840.0
ZNF337 9816.0
ZNF460 9751.0
UBE2S 9716.0
ZNF333 9710.0
YWHAH 9707.0
ZNF420 9691.0
ZNF304 9657.0
DDB2 9626.0
ZNF761 9625.0
ZNF738 9621.0
BAX 9620.0
H3C2 9609.0
SLC2A3 9566.0
ZNF613 9528.0
FOS 9527.0
CDK4 9521.0
JUN 9518.0
GTF2H3 9509.0
TAF6 9485.0
DDIT4 9455.0
PSMC1 9440.0
ZNF691 9419.0
TRIM28 9401.0
SMAD4 9393.0
KMT2B 9387.0
ZNF587 9379.0
NR4A2 9376.0
CSNK2A1 9373.0
RAD1 9369.0
ZNF658 9356.0
GAD2 9349.0
GATA3 9341.0
SNRPF 9329.0
REST 9290.0
RNU12 9260.0
POLR2K 9241.0
H3C8 9237.0
H2AJ 9219.0
CDC26 9208.0
L3MBTL1 9206.0
COX6A1 9203.0
ZNF562 9194.0
RBM8A 9140.0
ZNF37A 9136.0
ZNF668 9089.0
ZNF101 9082.0
ZNF776 9077.0
ZNF33A 9073.0
RPRD2 9072.0
MDM2 9066.0
ZNF212 9049.0
TCEA1 9025.0
ZNF626 9014.0
ZNF426 9003.0
IL6 8975.0
CDKN2B 8957.0
POLR2C 8943.0
COX16 8939.0
SNRPD3 8937.0
H4C3 8934.0
ZNF33B 8926.0
MED30 8913.0
ZFP69B 8912.0
SERPINE1 8895.0
TFAP2B 8891.0
SARNP 8886.0
ZNF709 8884.0
ZNF703 8876.0
COX11 8860.0
CCN2 8854.0
SIN3A 8850.0
ZNF681 8849.0
ZNF679 8832.0
TP53INP1 8822.0
ESRRA 8803.0
RBX1 8801.0
DLX5 8799.0
INTS13 8798.0
ZNF764 8796.0
RBL2 8791.0
H4C8 8774.0
GADD45A 8772.0
CITED2 8769.0
SUPT4H1 8759.0
H2AC20 8751.0
SNW1 8694.0
NR4A3 8668.0
SP1 8660.0
TAF9 8654.0
PSMD4 8637.0
PPARD 8620.0
DYRK2 8607.0
TAF11 8593.0
NOP2 8577.0
PSME2 8563.0
YBX1 8540.0
THRA 8535.0
CPSF2 8530.0
PTPN11 8498.0
SRSF1 8484.0
RABGGTB 8483.0
ZNF496 8475.0
ZNF747 8469.0
PRDM7 8434.0
PSMD7 8416.0
CAV1 8413.0
SKP1 8408.0
ZSCAN32 8379.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
HEY1 8360.0
ZNF248 8345.0
H3-3B 8344.0
RAD17 8341.0
ZNF235 8320.0
OCLN 8312.0
APOE 8293.0
TP53 8272.0
ZNF431 8262.0
PSMB3 8251.0
TTC5 8248.0
PCF11 8247.0
ZNF432 8232.0
ITGA5 8230.0
RNU4ATAC 8220.0
ZNF547 8189.0
POLR2D 8181.0
PERP 8162.0
PCNA 8157.0
BBC3 8101.0
SUPT16H 8100.0
EAF2 8087.0
ZNF189 8036.0
TACO1 8003.0
H2BC9 7978.5
H3C7 7978.5
NR2F6 7977.0
ZNF614 7972.0
ZNF253 7945.0
CDK5 7920.0
INTS12 7910.0
PSMC6 7899.0
TRPC3 7896.0
HES1 7880.0
THOC7 7879.0
CDC40 7861.0
RBBP5 7851.0
RB1 7836.0
H2BC21 7828.0
ZNF555 7799.0
CEBPB 7763.0
BTG2 7744.0
ANAPC11 7732.0
CBX8 7728.0
LAMTOR2 7721.0
RNU11 7714.0
RPS27A 7698.0
NR2C2AP 7687.0
XPO1 7679.0
ZNF385A 7669.0
PARP1 7668.0
ZNF417 7659.0
MYC 7649.0
NR2F1 7623.0
APAF1 7616.0
NBN 7592.0
ZNF114 7563.0
GATA2 7561.0
ZNF100 7554.0
H2AC18 7550.5
H2AC19 7550.5
CHEK1 7547.0
RNMT 7539.0
ZNF649 7538.0
ZNF419 7532.0
CDC25C 7483.0
RARA 7478.0
CAMK4 7451.0
PAF1 7448.0
ZNF136 7430.0
ATF2 7405.0
CDK1 7383.0
SRSF3 7367.0
E2F5 7351.0
RBL1 7321.0
UBB 7319.0
H3C4 7298.0
ZKSCAN1 7268.0
ZNF300 7232.0
BRD2 7223.0
MIR137 7219.0
PIP4K2C 7206.0
E2F1 7180.0
CBX5 7179.0
KCTD15 7175.0
PRDX2 7131.0
MAPKAPK5 7097.0
ZNF215 7073.0
GPAM 7071.0
PSMC3 7021.0
SKP2 7007.0
BGLAP 6986.0
PPP2R1A 6985.0
BMP2 6973.0
TRIAP1 6965.0
BRPF3 6951.0
G6PC1 6942.0
DDX39A 6916.0
ZNF138 6902.0
HDAC2 6890.0
RPAP2 6882.0
PSMB9 6881.0
ZNF28 6870.0
ZNF565 6847.0
H2BC3 6830.0
MED24 6814.0
ZNF684 6812.0
PSMA2 6802.0
ZNF154 6801.0
CCNG2 6795.0
MDC1 6793.0
HDAC1 6791.0
THOC5 6782.0
HDAC11 6749.0
TPX2 6742.0
INS 6737.0
CITED4 6716.0
MLLT3 6705.0
ICE1 6704.0
TEAD2 6687.0
YWHAB 6683.0
CDK5R1 6681.0
CDC16 6674.0
ZNF200 6652.0
CBX4 6634.0
H2BC5 6618.0
CTLA4 6617.0
TNRC6C 6608.0
MDM4 6604.0
ZNF510 6589.0
NR2E1 6588.0
TFAP2E 6567.0
TAF12 6560.0
ZNF551 6543.0
SRSF6 6524.0
LAMTOR4 6497.0
ZNF30 6493.0
H2AZ2 6467.0
YEATS4 6451.0
COX8A 6428.0
BID 6401.0
RORC 6395.0
GTF2F1 6376.0
AURKB 6374.0
ZNF225 6373.0
PRKAG1 6346.0
ANAPC16 6333.0
YY1 6328.0
ZNF398 6326.0
UBE2D3 6315.0
ZNF257 6295.0
ZNF548 6293.0
ZNF92 6288.0
ZNF577 6267.0
ZNF302 6259.0
TEAD3 6249.0
DLX6 6191.0
HDAC5 6156.0
USP2 6149.0
ZNF25 6138.0
CNOT9 6134.0
ZNF770 6133.0
SUPT6H 6127.0
RRAGC 6100.0
CNOT6 6096.0
ZNF792 6089.0
GAD1 6074.0
POLR2I 6073.0
SCO1 6031.0
H2BC10 6026.0
TAF15 6021.0
ZNF267 5992.0
ALYREF 5973.0
POU4F1 5954.0
AURKA 5943.0
YWHAZ 5941.0
ZC3H11A 5928.0
ZNF724 5918.0
ZNF14 5914.0
PSMD12 5909.0
SNRPG 5906.0
DNA2 5890.0
ZNF211 5879.0
NFKB1 5873.0
PCGF6 5854.0
ABCA6 5853.0
NOTCH3 5829.0
RBM14 5824.0
ZNF791 5798.0
PSMA3 5797.0
MED4 5779.0
PHAX 5778.0
JMY 5771.0
MED7 5769.0
CPSF6 5763.0
BTG1 5753.0
KMT2A 5747.0
PSMC2 5730.0
PSMA1 5699.0
TNRC6B 5666.0
THOC6 5656.0
PPP1R13L 5653.0
CBX3 5646.0
PRDX5 5643.0
HNF4G 5641.0
SMARCD3 5619.0
HAND2 5613.0
SESN3 5610.0
FOXO1 5586.0
ZNF692 5559.0
ING2 5554.0
DDIT3 5545.0
ERBB2 5530.0
PSMB4 5511.0
INTS10 5483.0
SMAD2 5479.0
CCND1 5472.0
ZNF732 5468.0
PSMA7 5457.0
CSTF1 5452.0
EXO1 5408.0
GLS2 5406.0
ITGA4 5389.0
ZNF99 5387.0
ZNF700 5356.0
ZNF557 5346.0
SMARCD1 5300.0
BLK 5299.0
PRKACA 5275.0
PSMC5 5252.0
FYTTD1 5205.0
H3C11 5197.0
FAS 5154.0
ATR 5120.0
GTF2E1 5096.0
RFFL 5073.0
CHEK2 5061.0
NABP2 5030.0
CNOT10 5011.0
ZNF730 4988.0
PSMA4 4968.0
CREB1 4963.0
ZNF394 4953.0
POLR2H 4937.0
ZNF461 4933.0
MGA 4927.0
SMARCE1 4912.0
ZNF208 4895.0
NR3C1 4868.0
RAD9B 4864.0
PIP4K2B 4846.0
ZNF543 4834.0
CLP1 4800.0
ZNF615 4794.0
TXN 4768.0
SRSF11 4767.0
RFC5 4755.0
ZNF559 4746.0
ZNF582 4738.0
ZNF184 4694.0
ATM 4677.0
NCBP2 4667.0
RAD51 4665.0
MAPK14 4661.0
SLBP 4643.0
TWIST1 4642.0
ZNF439 4608.0
ZNF214 4588.0
AGO3 4561.0
PPM1D 4547.0
GATA4 4543.0
INTS4 4542.0
ZNF45 4497.0
ZNF490 4484.0
H2BC15 4475.0
KIT 4471.0
WRN 4437.0
MAF 4428.0
TNFRSF10A 4404.0
POMC 4378.0
NDUFA4 4368.0
GPRIN1 4350.0
ZNF205 4345.0
ZNF740 4339.0
ELOC 4336.0
LSM11 4319.0
ITCH 4318.0
YAP1 4311.0
INTS2 4293.0
ZNF286A 4278.0
ARNT 4269.0
SRSF2 4267.0
SRSF7 4237.0
PRMT5 4230.0
CNOT11 4226.0
CNOT8 4200.0
MEAF6 4190.0
PSMD3 4188.0
SNRPE 4155.0
JAG1 4149.0
SNAPC3 4102.0
CSNK2A2 4101.0
SMARCD2 4099.0
CR1 4096.0
CTNNB1 4071.0
FANCD2 4063.0
ZNF18 4055.0
GTF2E2 4033.0
NR3C2 4018.0
SPP1 4006.0
BRPF1 3992.0
RFC4 3986.0
ZNF778 3976.0
ZNF611 3965.0
RAD50 3962.0
TBP 3926.0
ZNF566 3920.0
FBXO32 3913.0
CDC23 3912.0
PML 3902.0
BARD1 3901.0
PRKCQ 3885.0
PRKAG3 3879.0
CCNG1 3857.0
MED13 3829.0
ZSCAN25 3825.0
ANAPC10 3818.0
ZNF160 3812.0
ZNF875 3810.0
NELFE 3794.0
ZNF254 3772.0
YWHAG 3771.0
RSPO3 3764.0
RXRG 3715.0
SMARCC2 3708.0
ZNF688 3695.0
INTS14 3659.0
TGIF1 3642.0
GRIN2A 3606.0
MYB 3605.0
SSRP1 3594.0
ZNF521 3593.0
IL2 3567.0
ZNF544 3560.0
CDK2 3557.0
PRDM1 3540.0
ELOB 3538.0
ZNF549 3525.0
ZNF20 3508.0
NPM1 3477.0
THOC1 3438.0
RORB 3431.0
ZNF655 3408.0
COX6B1 3402.0
NLRC4 3399.0
PSMC4 3370.0
RPA3 3368.0
MED6 3361.0
POLR2B 3342.0
ZNF227 3337.0
ZNF324B 3336.0
ZNF418 3331.0
COX5A 3323.0
SMYD2 3322.0
MIR132 3316.0
ZNF500 3310.0
TFAP2D 3303.0
PAPOLA 3288.0
RYBP 3277.0
PRDX1 3266.0
U2AF1L4 3251.0
RHNO1 3243.0
PSMD1 3237.0
ZNF599 3203.0
H2BC8 3188.0
TNFRSF10B 3183.0
CDK12 3157.0
ACTL6A 3151.0
CBX2 3150.0
MED20 3134.0
ZNF415 3102.0
ZNF774 3074.0
H2AC8 3039.0
ZNF71 3037.0
AIFM2 3035.0
CCND3 3034.0
FBXW7 3005.0
ZNF264 2985.0
ZNF664 2981.0
COX7A2L 2957.0
CDKN2A 2953.0
RELA 2935.0
ZNF436 2893.0
ANAPC4 2868.0
TCF7L1 2867.0
TEAD1 2842.0
ZNF746 2834.0
POLR2G 2774.0
PSMD5 2770.0
CNOT2 2760.0
ICE2 2756.0
E2F4 2753.0
NR1D1 2747.0
NOTCH2 2736.0
NFYC 2732.0
ANAPC1 2721.0
HUS1 2686.0
ZNF26 2679.0
GPI 2675.0
NFYB 2667.0
DLL1 2647.0
ZNF143 2646.0
NPY 2634.0
SNAPC5 2617.0
RBPJ 2585.0
CDK7 2530.0
ZNF169 2499.0
PIP4P1 2468.0
ZNF771 2457.0
TFAP2A 2454.0
CSNK2B 2449.0
MAGOHB 2447.0
ZNF839 2438.0
ZNF624 2422.0
SKIL 2411.0
DDX39B 2385.0
H4C16 2382.0
GTF2A2 2375.0
GATAD2B 2336.0
MED31 2314.0
GRIN2B 2306.0
H3C3 2303.0
CSTF2T 2301.0
PF4 2258.0
IGFBP3 2254.0
GSK3B 2248.0
ZNF564 2242.0
BRCA1 2223.0
GTF2F2 2212.0
TNFRSF10D 2201.0
HIPK1 2169.0
ZNF529 2166.0
ZNF567 2162.0
FOXO6 2155.0
PSMB10 2137.0
ITGA2B 2129.0
CYCS 2106.0
COX5B 2064.0
ZNF140 1995.0
CNOT7 1938.0
AGRP 1932.0
ZIM2 1929.0
KAT2B 1876.0
POLR2E 1875.0
ZC3H8 1858.0
TXNRD1 1836.0
NR1D2 1768.0
RMI1 1759.0
PABPN1 1738.0
ITGAL 1731.0
ESR1 1723.0
PSMB1 1698.0
DAXX 1689.0
ELL 1681.0
ZNF704 1680.0
ZNF483 1652.0
TOP3A 1628.0
LMO2 1620.0
BCL6 1577.0
SOX2 1572.0
ZNF468 1541.0
ZNF721 1521.0
COL1A1 1500.0
ZNF175 1483.0
RPA2 1446.0
SRSF5 1443.0
SRF 1400.0
ZFP1 1386.0
WWP1 1363.0
MEN1 1353.0
MAGOH 1349.0
LEO1 1323.0
MRE11 1313.0
H4C2 1279.0
PSMA8 1258.0
PDPK1 1252.0
PPP2CB 1242.0
KRAS 1222.0
GLS 1210.0
PSMD2 1209.0
CCND2 1203.0
TBX5 1181.0
ZNF350 1174.0
SNAPC2 1169.0
SMAD1 1153.0
YWHAE 1143.0
PITX2 1125.0
H4C11 1080.0
TAF13 1052.0
ZNF775 1048.0
PSMD9 1039.0
PRKAA2 1038.0
SRRM1 1034.0
TXNIP 1032.0
ZNF589 1014.0
TEAD4 1011.0
SIRT3 1010.0
NUDT21 1004.0
PRELID3A 994.0
IL3 990.0
RARG 986.0
ZNF716 972.0
HEY2 958.0
ELF1 927.0
MMP13 912.0
RNF2 899.0
ZNF585B 895.0
ZNF680 889.0
PCGF5 884.0
NKX3-2 874.0
MYBL2 856.0
CCNH 840.0
CTR9 827.0
H2BC13 823.0
CHTOP 815.0
ERCC2 808.0
ELF2 806.0
PSMD14 794.0
ZNF256 790.0
ZNF620 786.0
CSTF3 775.0
MAML2 744.0
ZNF331 740.0
PRMT6 738.0
ZNF610 734.0
RRM2B 716.0
ZNF573 715.0
ZNF671 710.0
RXRB 709.0
VDR 673.0
CCNE2 668.0
KAT5 642.0
SESN1 639.0
COX19 623.0
KAT6A 601.0
LMO1 588.0
OPRM1 583.0
CPSF4 582.0
SST 575.0
NABP1 556.0
ZNF727 516.0
MED15 515.0
CDK13 481.0
PTEN 429.0
EPC1 417.0
SOCS3 413.0
PSMD11 411.0
PSMA5 410.0
NFATC2 399.0
TGFB1 382.0
ZNF382 376.0
MBD3 347.0
KMT2C 331.0
TNFRSF18 288.0
NR2C1 281.0
ZNF263 255.0
ZNF383 228.0
ZNF311 225.0
ZNF616 224.0
SOCS4 221.0
GTF2H5 189.0
MED23 129.0
ZNF195 119.0
CDC27 89.0
CAT 83.0
BNIP3L 52.0
ANAPC7 43.0
ZNF274 41.0
SESN2 31.0
ZNF268 1.0
TBL1XR1 0.0
ESR2 -43.0
RUNX2 -52.0
CBFB -58.0
ZNF621 -78.0
PPP2CA -89.0
ZNF782 -105.0
ZNF696 -108.0
SLU7 -122.0
TAF3 -130.0
PSMB5 -134.0
BCL2L11 -152.0
SRRT -154.0
PCGF2 -220.0
ZNF429 -260.0
ZNF266 -266.0
ZNF226 -278.0
WWTR1 -284.0
NFYA -287.0
ZNF678 -289.0
ZNF546 -290.0
ZKSCAN5 -293.0
RXRA -296.0
NR4A1 -299.0
ZNF773 -325.0
UBE2E1 -331.0
H4C6 -340.0
KDM5B -371.0
FANCI -373.0
MED10 -382.0
CPSF3 -389.0
NR5A2 -390.0
PTPN1 -391.0
COX18 -399.0
RBBP4 -414.0
ZNF19 -479.0
CDKN1B -509.0
COX20 -511.0
TFDP2 -533.0
INTS6 -541.0
ZNF554 -564.0
CNOT4 -572.0
CCNB1 -600.0
SETD1B -628.0
TAF4B -638.0
UBC -640.0
CHD4 -663.0
NELFCD -676.0
NR1H4 -687.0
YWHAQ -694.0
ATAD2 -702.0
GTF2B -706.0
CAMK2D -728.0
ZNF484 -731.0
CDKN1A -800.0
CAMK2G -811.0
HDAC10 -831.0
ESRRB -839.0
MSH2 -846.0
NFE2 -867.0
ZNF416 -870.0
ZNF607 -874.0
CCNE1 -881.0
CCNA1 -892.0
ZNF133 -911.0
CPSF7 -931.0
RARB -949.0
BANP -976.0
EIF4A3 -993.0
NR5A1 -1028.0
EP300 -1043.0
SUZ12 -1050.0
ZNF324 -1058.0
CHD3 -1071.0
ZNF697 -1090.0
TCF7L2 -1101.0
ZNF2 -1137.0
RICTOR -1154.0
SMURF2 -1158.0
ZNF141 -1180.0
KCTD1 -1182.0
ZNF586 -1192.0
PSMD13 -1223.0
ZNF3 -1234.0
MLH1 -1249.0
NR1H3 -1263.0
LBR -1269.0
TIGAR -1274.0
H2BC12 -1288.0
PPP2R5C -1316.0
BRIP1 -1317.0
SP7 -1340.0
PCBP4 -1355.0
CCNT1 -1363.0
ZFP90 -1375.0
ARID1B -1385.0
SGK1 -1399.0
ZNF75A -1420.0
RPRD1A -1427.0
AFF4 -1434.0
STK11 -1467.0
CGB8 -1478.0
ZNF222 -1482.0
TAF2 -1487.0
RBBP8 -1495.0
BDNF -1532.0
SUPT5H -1539.0
ZNF250 -1555.0
H2AZ1 -1561.0
RUNX3 -1564.0
ZNF202 -1587.0
MAML3 -1612.0
ELOA2 -1620.0
TNKS1BP1 -1637.0
ELL3 -1657.0
CDC7 -1658.0
ZNF234 -1670.0
RET -1702.0
ZNF23 -1703.0
CARM1 -1729.0
GTF2H1 -1760.0
ZNF180 -1768.0
LAMTOR3 -1769.0
PBRM1 -1770.0
SMARCA4 -1775.0
COX4I1 -1776.0
ZNF669 -1790.0
INTS8 -1801.0
PLXNA4 -1807.0
PPARGC1A -1810.0
ZNF430 -1814.0
ZNF662 -1822.0
POLDIP3 -1826.0
SMAD7 -1829.0
ZNF641 -1837.0
ARID2 -1840.0
IWS1 -1844.0
MSX2 -1857.0
ZNF213 -1896.0
E2F7 -1898.0
PRKCB -1916.0
ZFP30 -1919.0
ZNF446 -1993.0
SOD2 -2013.0
H2BC4 -2033.0
CDK6 -2037.0
ELL2 -2052.0
INTS9 -2055.0
TCF3 -2071.0
ZFHX3 -2078.0
H3C10 -2100.0
ZNF571 -2113.0
MTA2 -2122.0
RFC3 -2132.0
NEDD4L -2142.0
TJP1 -2147.0
ZNF540 -2185.0
HDAC3 -2207.0
RNF111 -2237.0
LGALS3 -2256.0
PSME3 -2265.0
PGR -2281.0
RPA1 -2286.0
ZNF282 -2293.0
SYMPK -2295.0
KAT2A -2329.0
ARID1A -2337.0
H4C13 -2348.0
ATXN3 -2353.0
PTPN4 -2375.0
EHMT2 -2398.0
NRBP1 -2446.0
ZNF790 -2456.0
SMAD6 -2459.0
ZNF224 -2461.0
STEAP3 -2490.0
ZNF77 -2527.0
ITGBL1 -2530.0
PPARG -2536.0
RRAGD -2541.0
HNF4A -2544.0
ZNF317 -2574.0
AGO1 -2599.0
ASH2L -2601.0
INTS7 -2616.0
ZNF43 -2627.0
SIRT1 -2694.0
CUL1 -2716.0
ZNF485 -2724.0
TCF12 -2729.0
SMARCA2 -2731.0
ZNF433 -2764.0
H4C12 -2774.0
NOTCH4 -2786.0
ZNF273 -2799.0
ZKSCAN7 -2823.0
KRBOX5 -2844.0
UBE2C -2846.0
UBA52 -2875.0
ZNF714 -2907.0
TP53I3 -2934.0
ZNF706 -2977.0
MED25 -2978.0
PPARGC1B -2992.0
PSMB7 -2995.0
POU2F1 -3010.0
RFC2 -3028.0
ARID3A -3039.0
YES1 -3041.0
PSME4 -3042.0
ZNF568 -3060.0
ZNF726 -3061.0
PRELID1 -3069.0
SUMO1 -3074.0
ZNF287 -3093.0
ANAPC5 -3127.0
PIDD1 -3158.0
GAMT -3185.0
ZNF354B -3202.0
KMT5A -3229.0
IGFBP1 -3241.0
NCBP1 -3261.0
ZNF197 -3272.0
H4C9 -3283.0
ZNF597 -3325.0
ZNF443 -3331.0
ZNF606 -3335.0
MED8 -3356.0
H2AC6 -3373.0
MAPK11 -3435.0
MEF2C -3436.0
MNAT1 -3468.0
EHMT1 -3490.0
SRC -3509.0
ZNF660 -3514.0
ZNF596 -3520.0
GRIA2 -3527.0
IQSEC3 -3540.0
EZH2 -3560.0
NR6A1 -3563.0
CRH -3570.0
RORA -3581.0
CCNC -3599.0
ZNF708 -3600.0
PINK1 -3606.0
NKX2-5 -3609.0
PHC3 -3621.0
CCNA2 -3622.0
IL2RA -3625.0
LSM10 -3629.0
USP7 -3676.0
TP73 -3680.0
EED -3682.0
ZNF74 -3695.0
SREBF1 -3702.0
RRM2 -3706.0
NR2C2 -3713.0
NCOR1 -3721.0
MLLT1 -3729.0
PRKAG2 -3730.0
POU2F2 -3737.0
PIP4K2A -3752.0
RUNX1 -3762.0
L3MBTL2 -3768.0
HIVEP3 -3769.0
PVALB -3771.0
FIP1L1 -3812.0
SURF1 -3822.0
SNRPB -3828.0
ZNF343 -3831.0
DHX38 -3833.0
CALM1 -3834.0
POLR2F -3844.0
ZFP14 -3858.0
SATB2 -3862.0
ZNF793 -3871.0
CLDN5 -3885.0
PSMA6 -3897.0
RPTOR -3900.0
ZNF425 -3902.0
SFN -3911.0
CDK8 -3946.0
STAT1 -3961.0
ZNF584 -3973.0
VEGFA -3998.0
ATRIP -4017.0
SMURF1 -4025.0
NDRG1 -4053.0
GTF2H4 -4059.0
SMARCB1 -4062.0
SNAPC1 -4117.0
RNF34 -4121.0
PCK1 -4128.0
SMARCC1 -4158.0
EGFR -4211.0
MET -4214.0
ESRRG -4248.0
PSMB2 -4270.0
CCNT2 -4284.0
ZNF79 -4325.0
ZNF486 -4389.0
POLR2L -4399.0
IFNG -4435.0
DGCR8 -4444.0
INTS5 -4463.0
ZKSCAN8 -4473.0
MLST8 -4487.0
GSR -4493.0
WDR33 -4495.0
ZKSCAN3 -4514.0
BMI1 -4555.0
ZNF440 -4587.0
GPS2 -4594.0
TFAP2C -4607.0
RPRD1B -4608.0
SETD9 -4631.0
H4C5 -4637.0
RRAGA -4638.0
SOX9 -4676.0
HDAC4 -4715.0
PAX5 -4724.0
IHH -4743.0
SEM1 -4777.0
SIN3B -4783.0
CNOT6L -4821.0
CCNK -4838.0
KCNIP3 -4841.0
PHC1 -4846.0
ZNF561 -4860.0
ABL1 -4874.0
H4C4 -4917.0
TRIM63 -4937.0
PPP1R13B -4945.0
ZNF552 -4960.0
TAF4 -4971.0
MAP2K6 -4983.0
MAPKAP1 -4986.0
ZIM3 -4990.0
RBFOX3 -5002.0
BLM -5013.0
TAF7 -5022.0
PSMD8 -5041.0
HSPD1 -5048.0
GLI3 -5050.0
RBFOX1 -5084.0
MIR27A -5092.0
H2AX -5114.0
SERPINB13 -5143.0
MED26 -5147.0
RTF1 -5148.0
ZNF334 -5183.0
OPRK1 -5186.0
ANAPC15 -5225.0
TSC1 -5231.0
ZNF785 -5245.0
GCK -5270.0
MTOR -5272.0
SRSF9 -5277.0
AGO2 -5311.0
MED16 -5318.0
CRADD -5328.0
NRBF2 -5342.0
TP53BP2 -5369.0
PIN1 -5386.0
TNRC6A -5391.0
AUTS2 -5430.0
ZNF454 -5469.0
PSMF1 -5472.0
E2F8 -5555.0
LIFR -5560.0
TAL1 -5570.0
ZNF479 -5626.0
TRIM33 -5629.0
EAF1 -5630.0
CGA -5632.0
ZNF619 -5639.0
KRBA1 -5674.0
ZNF749 -5706.0
ZFP69 -5718.0
ZNF677 -5741.0
ZNF10 -5761.0
ZNF625 -5795.0
ZNF34 -5804.0
PRR5 -5815.0
H2BC11 -5816.0
ZNF600 -5836.0
SCMH1 -5843.0
ZNF710 -5859.0
FKBP5 -5909.0
CTSK -5955.0
ZNF550 -5960.0
PRKAA1 -5970.0
PSMD6 -5971.0
MED27 -6008.0
ZNF493 -6015.0
RNGTT -6046.0
CPSF1 -6053.0
YAF2 -6058.0
ZNF470 -6083.0
ZNF221 -6139.0
INTS3 -6169.0
MED17 -6180.0
TP53RK -6208.0
CNOT3 -6228.0
LRPPRC -6245.0
ZNF12 -6263.0
MOBP -6280.0
PRMT1 -6289.0
ZFP2 -6296.0
BRD7 -6338.0
ZNF155 -6341.0
HIPK2 -6360.0
ZNF799 -6376.0
VENTX -6394.0
ELOA -6416.0
PLAGL1 -6425.0
MIR24-2 -6429.0
UCMA -6434.0
INTS11 -6460.0
HDAC9 -6481.0
KLF4 -6490.0
CSF1R -6494.0
BCL2L14 -6500.0
MAX -6513.0
GTF2A1 -6537.0
ZNF682 -6542.0
E2F6 -6574.0
TFDP1 -6580.0
CDK9 -6583.0
MED1 -6624.0
SKI -6632.0
AKT1 -6634.0
NELFB -6659.0
H2BC26 -6669.0
TNFRSF10C -6703.0
FANCC -6736.0
MAPK1 -6741.0
RNPS1 -6758.0
CNOT1 -6783.0
POU4F2 -6795.0
STUB1 -6825.0
FOXO3 -6829.0
NCOR2 -6856.0
KCTD6 -6857.0
AGO4 -6858.0
PSMB6 -6874.0
TOPBP1 -6907.0
NR1H2 -6910.0
RMI2 -6927.0
CASC3 -7100.0
UBE2D1 -7157.0
ZNF480 -7195.0
CREBBP -7206.0
CAMK2B -7212.0
RABGGTA -7236.0
PRKAB2 -7244.0
ZNF583 -7250.0
SRSF4 -7270.0
POLR2J -7312.0
PPARA -7329.0
FZR1 -7345.0
COX7C -7372.0
CAMK2A -7375.0
SMAD3 -7379.0
CASP6 -7384.0
PHC2 -7388.0
GLI2 -7420.0
NELFA -7439.0
MAPK3 -7453.0
PMS2 -7455.0
RING1 -7507.0
WWOX -7513.0
ZNF707 -7518.0
SSU72 -7537.0
POLR2A -7563.0
CDC73 -7566.0
TAF8 -7568.0
SLC38A9 -7574.0
H2BC1 -7617.0
NAMPT -7624.0
CENPJ -7669.0
COX6C -7672.0
ZNF667 -7710.0
ZNF670 -7724.0
RAD51D -7740.0
ZNF689 -7769.0
NR1I2 -7789.0
SETD1A -7793.0
ZNF585A -7815.0
ZNF737 -7819.0
TWIST2 -7832.0
PLK2 -7841.0
COL1A2 -7903.0
ZNF492 -7904.0
ZNF445 -7959.0
SYT10 -7965.0
TP63 -7978.0
ACTL6B -7985.0
AKT2 -8044.0
ZNF772 -8047.0
ZNF569 -8093.0
PRKAB1 -8100.0
AKT3 -8134.0
ZNF135 -8147.0
PHF20 -8195.0
ZNF750 -8205.0
PSME1 -8232.0
ZNF777 -8256.0
TMEM219 -8281.0
HTT -8299.0
U2AF2 -8312.0
ZIK1 -8345.0
UBE2I -8350.0
RHEB -8364.0
KMT2E -8372.0
CASP1 -8384.0
ZNF560 -8388.0
ZNF517 -8411.0
NOTCH1 -8493.0
FOXG1 -8501.0
DEK -8516.0
MOV10 -8523.0
PPP2R1B -8545.0
PPM1A -8630.0
CTDP1 -8635.0
ZFPM1 -8671.0
BIRC5 -8677.0
GATAD2A -8692.0
ZNF570 -8756.0
ZNF665 -8807.0
ZNF605 -8818.0
ZNF713 -8837.0
ZNF441 -8851.0
NPAS4 -8853.0
TAF5 -8856.0
MSTN -8984.0
BMAL1 -8988.0
HDAC7 -9005.0
THRB -9047.0
RAD9A -9062.0
ZNF675 -9098.0
GPX2 -9101.0
PSMB11 -9151.0
TSC2 -9163.0
CBX6 -9190.0
ZFP37 -9193.0
ZNF506 -9208.0
ZNF442 -9242.0
SCO2 -9255.0
ZNF230 -9267.0
KMT2D -9368.0
NUAK1 -9398.0
NOC2L -9413.0
CASP2 -9455.0
SPI1 -9488.0
ANAPC2 -9497.0
ARNT2 -9511.0
THBS1 -9517.0
ING5 -9519.0
LAMTOR1 -9552.0
CASP10 -9553.0
SNAPC4 -9559.0
ERCC3 -9580.0
BRD1 -9585.0
ZNF729 -9595.0
INTS1 -9598.0
NR2E3 -9610.0
TP53AIP1 -9617.0
ZNF563 -9669.0
THOC3 -9696.0
ZNF223 -9741.0
ZNF804B -9773.0
ZNF471 -9866.0
ZNF514 -9921.0
ZNF528 -9950.0
WDR5 -9985.0
ZNF558 -10028.0
CSF2 -10103.0
ZFP28 -10144.0
AXIN1 -10153.0
CTSL -10161.0
NR1I3 -10203.0
TGFA -10241.0
MAML1 -10262.0
ZNF701 -10272.0
ZNF736 -10286.0
ZNF556 -10291.0
TAF1L -10328.0
ZNF112 -10329.0
GP1BA -10330.0
FURIN -10395.0
ZNF530 -10428.0
ZNF347 -10475.0
ZNF735 -10476.0
ZNF699 -10534.0
ZNF354C -10549.0
MYL9 -10556.0
ZNF124 -10672.0
MIR24-1 -10931.0
ZNF285 -10974.0
CGB5 -10983.0
NR0B2 -11039.0



REACTOME_SARS_COV_2_MODULATES_HOST_TRANSLATION_MACHINERY

REACTOME_SARS_COV_2_MODULATES_HOST_TRANSLATION_MACHINERY
1601
set REACTOME_SARS_COV_2_MODULATES_HOST_TRANSLATION_MACHINERY
setSize 46
pANOVA 2.12e-08
s.dist 0.477
p.adjustANOVA 2.32e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS5 10401.0
RPS13 10010.0
SNRPD2 9776.0
GEMIN7 9544.0
GEMIN2 9444.0
SNRPF 9329.0
RPS28 8978.0
SNRPD3 8937.0
RPS8 8920.0
RPS12 8794.0
RPS25 8638.0
RPS6 8501.0
SMN1 8480.5
SMN2 8480.5
RPS2 8109.0
FAU 8086.0
RPS3A 7941.0
RPS18 7868.0
RPS27A 7698.0
DDX20 7263.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS5 10401.0
RPS13 10010.0
SNRPD2 9776.0
GEMIN7 9544.0
GEMIN2 9444.0
SNRPF 9329.0
RPS28 8978.0
SNRPD3 8937.0
RPS8 8920.0
RPS12 8794.0
RPS25 8638.0
RPS6 8501.0
SMN1 8480.5
SMN2 8480.5
RPS2 8109.0
FAU 8086.0
RPS3A 7941.0
RPS18 7868.0
RPS27A 7698.0
DDX20 7263.0
RPS26 6957.0
RPS21 6901.0
SNRPG 5906.0
RPS29 5882.0
RPS15 5697.0
RPS15A 5210.0
RPS10 5051.0
RPS19 5043.0
RPS20 4727.0
SNRPE 4155.0
RPSA 3658.0
GEMIN6 2822.0
RPS24 2748.0
RPS16 2475.0
RPS27L 2308.0
RPS23 2004.0
RPS11 1269.0
RPS27 1132.0
RPS14 322.0
GEMIN4 -197.0
SNRPD1 -647.0
RPS3 -850.0
RPS9 -1972.0
RPS7 -3608.0
SNRPB -3828.0
GEMIN5 -4203.0



REACTOME_NEGATIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION

REACTOME_NEGATIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION
853
set REACTOME_NEGATIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION
setSize 100
pANOVA 2.76e-08
s.dist 0.321
p.adjustANOVA 2.83e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C12 10715
H2BC14 10635
H2AC14 10619
H2BC6 10447
H2BC17 10375
H4C1 10268
H2AC4 10244
SAP30 10201
H3C1 10183
H3C6 9987
SAP130 9965
H3C2 9609
GTF2H3 9509
POLR1H 9366
POLR2K 9241
H3C8 9237
H2AJ 9219
SMARCA5 9103
H4C3 8934
SIN3A 8850

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
H4C1 10268.0
H2AC4 10244.0
SAP30 10201.0
H3C1 10183.0
H3C6 9987.0
SAP130 9965.0
H3C2 9609.0
GTF2H3 9509.0
POLR1H 9366.0
POLR2K 9241.0
H3C8 9237.0
H2AJ 9219.0
SMARCA5 9103.0
H4C3 8934.0
SIN3A 8850.0
H4C8 8774.0
H2AC20 8751.0
RRP8 8525.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0
MBD2 8291.0
H2BC9 7978.5
H3C7 7978.5
H2BC21 7828.0
POLR1E 7682.0
TTF1 7629.0
H2AC18 7550.5
H2AC19 7550.5
H3C4 7298.0
TAF1A 7141.0
HDAC2 6890.0
H2BC3 6830.0
HDAC1 6791.0
UBTF 6759.0
H2BC5 6618.0
H2AZ2 6467.0
POLR1G 6379.0
H2BC10 6026.0
TAF1B 5541.0
H3C11 5197.0
POLR2H 4937.0
SUDS3 4716.0
SAP30BP 4705.0
H2BC15 4475.0
TBP 3926.0
ARID4B 3208.0
H2BC8 3188.0
POLR1D 3137.0
H2AC8 3039.0
POLR1A 2598.0
CDK7 2530.0
H4C16 2382.0
POLR1B 2328.0
H3C3 2303.0
POLR2E 1875.0
SAP30L 1779.0
SAP18 1491.0
H4C2 1279.0
H4C11 1080.0
CCNH 840.0
H2BC13 823.0
ERCC2 808.0
TAF1D 291.0
GTF2H5 189.0
H4C6 -340.0
H2BC12 -1288.0
TAF1C -1359.0
H2AZ1 -1561.0
GTF2H1 -1760.0
H2BC4 -2033.0
H3C10 -2100.0
H4C13 -2348.0
SIRT1 -2694.0
H4C12 -2774.0
H4C9 -3283.0
H2AC6 -3373.0
BAZ2A -3387.0
MNAT1 -3468.0
POLR2F -3844.0
GTF2H4 -4059.0
POLR2L -4399.0
POLR1C -4599.0
H4C5 -4637.0
SIN3B -4783.0
DNMT1 -4856.0
H4C4 -4917.0
H2AX -5114.0
DNMT3B -5772.0
H2BC11 -5816.0
H2BC26 -6669.0
H2BC1 -7617.0
POLR1F -9054.0
ERCC3 -9580.0



REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA

REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA
1146
set REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA
setSize 263
pANOVA 4.03e-08
s.dist 0.197
p.adjustANOVA 3.9e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
ZMAT2 10172
PHF5A 10133
CWC15 9904
SNRPD2 9776
SNU13 9681
SNRPA 9631
GLE1 9377
SNRPF 9329
POLR2K 9241
RBM8A 9140
ISY1 9061
RBM39 9022
LUC7L3 9021
PRPF4 8965
POLR2C 8943
SNRPD3 8937
HSPA8 8896
SARNP 8886
NXT1 8885
TXNL4A 8857

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ZMAT2 10172
PHF5A 10133
CWC15 9904
SNRPD2 9776
SNU13 9681
SNRPA 9631
GLE1 9377
SNRPF 9329
POLR2K 9241
RBM8A 9140
ISY1 9061
RBM39 9022
LUC7L3 9021
PRPF4 8965
POLR2C 8943
SNRPD3 8937
HSPA8 8896
SARNP 8886
NXT1 8885
TXNL4A 8857
HNRNPA1 8761
PPIL3 8750
CRNKL1 8699
SNW1 8694
SF3B5 8644
FUS 8636
HNRNPC 8571
LENG1 8570
YBX1 8540
CPSF2 8530
LSM7 8523
PRKRIP1 8517
SRSF1 8484
SRSF8 8381
PCF11 8247
WBP11 8200
POLR2D 8181
SF3B4 8174
NUP153 8090
USP39 8048
HNRNPL 7999
NUP58 7912
THOC7 7879
CDC40 7861
FAM32A 7860
PPWD1 7797
PTBP1 7790
PCBP1 7777
DDX46 7661
C9orf78 7600
LSM4 7420
SRSF3 7367
ZCRB1 7361
PDCD7 7359
DHX9 7301
SNRNP25 7151
UBL5 6954
SF3A3 6945
DDX39A 6916
THOC5 6782
BUD31 6756
PRPF19 6637
WTAP 6566
SRSF6 6524
GTF2F1 6376
RBM22 6365
EFTUD2 6296
NUP214 6207
NUP88 6185
ZNF830 6157
HNRNPU 6103
LSM8 6079
POLR2I 6073
NUP160 6067
ALYREF 5973
DHX35 5958
ZC3H11A 5928
SNRPG 5906
LSM5 5866
GCFC2 5816
METTL3 5773
CPSF6 5763
CWC25 5724
THOC6 5656
HNRNPK 5648
RANBP2 5556
SF3A2 5551
WBP4 5549
NUP62 5513
NUP35 5491
CSTF1 5452
NUP107 5390
BCAS2 5290
SEH1L 5251
FYTTD1 5205
HNRNPA2B1 5128
DDX23 5098
IK 5064
POLR2H 4937
METTL14 4902
CCAR1 4859
HNRNPD 4808
CLP1 4800
SRSF11 4767
NCBP2 4667
SLBP 4643
LSM2 4624
PRPF38A 4451
CWC27 4299
SRSF2 4267
SRSF7 4237
NUP37 4196
SNRPE 4155
SMU1 3766
PCBP2 3688
SMNDC1 3686
NUP54 3624
SYF2 3587
PNN 3569
EIF4E 3532
HNRNPR 3489
SF3B6 3468
NUP85 3458
THOC1 3438
SNRNP48 3372
POLR2B 3342
NUP50 3335
PAPOLA 3288
U2AF1L4 3251
PPIL1 3187
RBM7 3042
NUP133 2881
DDX41 2879
POLR2G 2774
SF3B3 2523
HNRNPA3 2501
MAGOHB 2447
DDX39B 2385
CSTF2T 2301
GTF2F2 2212
U2SURP 2211
AAAS 2175
SRSF10 2060
SDE2 1962
DDX42 1916
POLR2E 1875
DHX8 1752
TRA2B 1749
PABPN1 1738
LSM6 1612
SNRPN 1552
SF1 1544
CCDC12 1534
SAP18 1491
SRSF5 1443
MAGOH 1349
NXF1 1289
SNIP1 1257
PPIH 1205
BUD13 1064
SRRM1 1034
NUDT21 1004
PRPF31 995
PRPF40A 918
HNRNPM 859
CHTOP 815
SF3B1 782
CSTF3 775
CPSF4 582
HNRNPH1 534
ZMAT5 484
RBM25 456
RBM17 362
NDC1 28
NUP155 -40
SNRNP35 -88
SLU7 -122
SRRT -154
DHX16 -264
HNRNPF -288
DDX5 -377
CPSF3 -389
SNRPA1 -644
SNRPD1 -647
PLRG1 -915
CPSF7 -931
PRPF18 -978
EIF4A3 -993
SF3B2 -995
CACTIN -1253
TPR -1291
NUP98 -1370
NUP42 -1491
CDC5L -1498
LSM3 -1616
NUP93 -1778
POLDIP3 -1826
WDR70 -2238
MFAP1 -2278
SYMPK -2295
SNRNP40 -2363
ACIN1 -2405
SNRPB2 -2424
RNPC3 -2497
RBM5 -2548
NUP188 -2578
TFIP11 -2728
DNAJC8 -2749
AQR -2768
NCBP1 -3261
NUP205 -3512
SNRPC -3551
DHX15 -3617
FIP1L1 -3812
SNRPB -3828
DHX38 -3833
POLR2F -3844
PRPF8 -3970
POLR2L -4399
WDR33 -4495
CWF19L2 -4566
NUP210 -4632
SEC13 -4820
PRCC -5135
RBM42 -5162
SRSF9 -5277
SNRNP27 -5486
PPIG -5700
MTREX -5758
NUP43 -6011
CPSF1 -6053
SF3A1 -6066
TCERG1 -6336
XAB2 -6417
POM121 -6621
RNPS1 -6758
PRPF6 -6865
CWC22 -6935
SRSF12 -6979
CASC3 -7100
PPIL4 -7129
SRRM2 -7130
SNRNP200 -7137
PUF60 -7159
RAE1 -7253
SRSF4 -7270
POLR2J -7312
NSRP1 -7471
POLR2A -7563
POM121C -7658
PPP1R8 -7777
PPIE -8126
U2AF2 -8312
SNRNP70 -8629
SUGP1 -8744
YJU2 -8859
CTNNBL1 -9023
PRPF3 -9233
CHERP -9359
PPIL2 -9370
GPATCH1 -9589
THOC3 -9696
SART1 -9806



REACTOME_DNA_REPLICATION_PRE_INITIATION

REACTOME_DNA_REPLICATION_PRE_INITIATION
1101
set REACTOME_DNA_REPLICATION_PRE_INITIATION
setSize 150
pANOVA 5.33e-08
s.dist 0.257
p.adjustANOVA 4.86e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C12 10715
H2BC14 10635
H2AC14 10619
H2BC6 10447
H2BC17 10375
H4C1 10268
H2AC4 10244
H3C1 10183
H3C6 9987
PSMB8 9883
UBE2S 9716
H3C2 9609
PSMC1 9440
H3C8 9237
H2AJ 9219
CDC26 9208
H4C3 8934
H4C8 8774
H2AC20 8751
POLE3 8715

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
H4C1 10268.0
H2AC4 10244.0
H3C1 10183.0
H3C6 9987.0
PSMB8 9883.0
UBE2S 9716.0
H3C2 9609.0
PSMC1 9440.0
H3C8 9237.0
H2AJ 9219.0
CDC26 9208.0
H4C3 8934.0
H4C8 8774.0
H2AC20 8751.0
POLE3 8715.0
PSMD4 8637.0
PSME2 8563.0
PSMD7 8416.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0
PSMB3 8251.0
PRIM1 8152.0
MCM5 8147.0
ORC6 8118.0
H2BC9 7978.5
H3C7 7978.5
PSMC6 7899.0
H2BC21 7828.0
ANAPC11 7732.0
RPS27A 7698.0
H2AC18 7550.5
H2AC19 7550.5
UBB 7319.0
H3C4 7298.0
ORC4 7082.0
PSMC3 7021.0
PSMB9 6881.0
H2BC3 6830.0
PSMA2 6802.0
CDC16 6674.0
MCM3 6656.0
H2BC5 6618.0
H2AZ2 6467.0
ANAPC16 6333.0
H2BC10 6026.0
KPNB1 5988.0
PSMD12 5909.0
PSMA3 5797.0
PSMC2 5730.0
PSMA1 5699.0
PSMB4 5511.0
PSMA7 5457.0
POLA2 5403.0
PSMC5 5252.0
H3C11 5197.0
POLE2 5028.0
PSMA4 4968.0
ORC2 4544.0
H2BC15 4475.0
ORC1 4331.0
PSMD3 4188.0
CDC23 3912.0
CDC6 3859.0
ANAPC10 3818.0
MCM2 3608.0
CDK2 3557.0
PSMC4 3370.0
RPA3 3368.0
PSMD1 3237.0
H2BC8 3188.0
H2AC8 3039.0
MCM6 2968.0
ANAPC4 2868.0
PSMD5 2770.0
ANAPC1 2721.0
H4C16 2382.0
H3C3 2303.0
PSMB10 2137.0
DBF4 1773.0
PSMB1 1698.0
RPA2 1446.0
H4C2 1279.0
PSMD2 1209.0
H4C11 1080.0
PSMD9 1039.0
PRIM2 961.0
MCM4 954.0
KPNA6 951.0
H2BC13 823.0
PSMD14 794.0
MCM8 737.0
PSMD11 411.0
PSMA5 410.0
CDC27 89.0
ANAPC7 43.0
PSMB5 -134.0
UBE2E1 -331.0
H4C6 -340.0
UBC -640.0
PSMD13 -1223.0
H2BC12 -1288.0
MCM10 -1298.0
H2AZ1 -1561.0
CDC7 -1658.0
CDC45 -1753.0
POLE -2012.0
H2BC4 -2033.0
H3C10 -2100.0
GMNN -2214.0
PSME3 -2265.0
RPA1 -2286.0
H4C13 -2348.0
H4C12 -2774.0
UBE2C -2846.0
UBA52 -2875.0
PSMB7 -2995.0
ANAPC5 -3127.0
H4C9 -3283.0
H2AC6 -3373.0
KPNA1 -3430.0
CDT1 -3492.0
PSMA6 -3897.0
PSMB2 -4270.0
H4C5 -4637.0
SEM1 -4777.0
H4C4 -4917.0
ORC3 -4974.0
PSMD8 -5041.0
H2AX -5114.0
ANAPC15 -5225.0
PSMF1 -5472.0
H2BC11 -5816.0
PSMD6 -5971.0
MCM7 -6234.0
H2BC26 -6669.0
PSMB6 -6874.0
ORC5 -6898.0
UBE2D1 -7157.0
FZR1 -7345.0
H2BC1 -7617.0
PSME1 -8232.0
ANAPC2 -9497.0
POLE4 -9664.0



REACTOME_ACTIVATED_PKN1_STIMULATES_TRANSCRIPTION_OF_AR_ANDROGEN_RECEPTOR_REGULATED_GENES_KLK2_AND_KLK3

REACTOME_ACTIVATED_PKN1_STIMULATES_TRANSCRIPTION_OF_AR_ANDROGEN_RECEPTOR_REGULATED_GENES_KLK2_AND_KLK3
916
set REACTOME_ACTIVATED_PKN1_STIMULATES_TRANSCRIPTION_OF_AR_ANDROGEN_RECEPTOR_REGULATED_GENES_KLK2_AND_KLK3
setSize 59
pANOVA 6.27e-08
s.dist 0.407
p.adjustANOVA 5.42e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
H4C1 10268.0
H2AC4 10244.0
KLK2 10225.0
H3C1 10183.0
KLK3 10088.0
H3C6 9987.0
H3C2 9609.0
H3C8 9237.0
H2AJ 9219.0
H4C3 8934.0
H4C8 8774.0
H2AC20 8751.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
H4C1 10268.0
H2AC4 10244.0
KLK2 10225.0
H3C1 10183.0
KLK3 10088.0
H3C6 9987.0
H3C2 9609.0
H3C8 9237.0
H2AJ 9219.0
H4C3 8934.0
H4C8 8774.0
H2AC20 8751.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0
H2BC9 7978.5
H3C7 7978.5
H2BC21 7828.0
H2AC18 7550.5
H2AC19 7550.5
H3C4 7298.0
H2BC3 6830.0
PKN1 6663.0
H2BC5 6618.0
H2AZ2 6467.0
H2BC10 6026.0
H3C11 5197.0
H2BC15 4475.0
H2BC8 3188.0
H2AC8 3039.0
KDM1A 2641.0
H4C16 2382.0
H3C3 2303.0
NCOA2 1402.0
H4C2 1279.0
H4C11 1080.0
H2BC13 823.0
KDM4C 292.0
H4C6 -340.0
H2BC12 -1288.0
H2AZ1 -1561.0
H2BC4 -2033.0
H3C10 -2100.0
H4C13 -2348.0
H4C12 -2774.0
H4C9 -3283.0
H2AC6 -3373.0
H4C5 -4637.0
H4C4 -4917.0
H2AX -5114.0
H2BC11 -5816.0
H2BC26 -6669.0
H2BC1 -7617.0



REACTOME_DNA_REPLICATION

REACTOME_DNA_REPLICATION
1113
set REACTOME_DNA_REPLICATION
setSize 178
pANOVA 7.81e-08
s.dist 0.233
p.adjustANOVA 6.26e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C12 10715
H2BC14 10635
H2AC14 10619
H2BC6 10447
H2BC17 10375
H4C1 10268
H2AC4 10244
H3C1 10183
H3C6 9987
PSMB8 9883
UBE2S 9716
H3C2 9609
PSMC1 9440
H3C8 9237
H2AJ 9219
CDC26 9208
H4C3 8934
RBX1 8801
H4C8 8774
H2AC20 8751

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
H4C1 10268.0
H2AC4 10244.0
H3C1 10183.0
H3C6 9987.0
PSMB8 9883.0
UBE2S 9716.0
H3C2 9609.0
PSMC1 9440.0
H3C8 9237.0
H2AJ 9219.0
CDC26 9208.0
H4C3 8934.0
RBX1 8801.0
H4C8 8774.0
H2AC20 8751.0
POLE3 8715.0
PSMD4 8637.0
PSME2 8563.0
PSMD7 8416.0
SKP1 8408.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0
POLD4 8324.0
PSMB3 8251.0
PCNA 8157.0
PRIM1 8152.0
MCM5 8147.0
ORC6 8118.0
H2BC9 7978.5
H3C7 7978.5
PSMC6 7899.0
H2BC21 7828.0
ANAPC11 7732.0
RPS27A 7698.0
H2AC18 7550.5
H2AC19 7550.5
UBB 7319.0
H3C4 7298.0
ORC4 7082.0
PSMC3 7021.0
SKP2 7007.0
PSMB9 6881.0
H2BC3 6830.0
PSMA2 6802.0
CDC16 6674.0
MCM3 6656.0
H2BC5 6618.0
H2AZ2 6467.0
ANAPC16 6333.0
GINS4 6164.0
H2BC10 6026.0
KPNB1 5988.0
PSMD12 5909.0
DNA2 5890.0
FEN1 5830.0
PSMA3 5797.0
PSMC2 5730.0
PSMA1 5699.0
PSMB4 5511.0
PSMA7 5457.0
POLA2 5403.0
PSMC5 5252.0
H3C11 5197.0
POLE2 5028.0
PSMA4 4968.0
GINS2 4947.0
GINS1 4852.0
RFC5 4755.0
ORC2 4544.0
H2BC15 4475.0
ORC1 4331.0
PSMD3 4188.0
RFC4 3986.0
CDC23 3912.0
CDC6 3859.0
ANAPC10 3818.0
MCM2 3608.0
CDK2 3557.0
PSMC4 3370.0
RPA3 3368.0
PSMD1 3237.0
H2BC8 3188.0
H2AC8 3039.0
MCM6 2968.0
ANAPC4 2868.0
PSMD5 2770.0
ANAPC1 2721.0
H4C16 2382.0
H3C3 2303.0
PSMB10 2137.0
DBF4 1773.0
PSMB1 1698.0
RPA2 1446.0
H4C2 1279.0
PSMA8 1258.0
PSMD2 1209.0
H4C11 1080.0
PSMD9 1039.0
PRIM2 961.0
MCM4 954.0
KPNA6 951.0
H2BC13 823.0
PSMD14 794.0
MCM8 737.0
CCNE2 668.0
PSMD11 411.0
PSMA5 410.0
CDC27 89.0
ANAPC7 43.0
PSMB5 -134.0
UBE2E1 -331.0
H4C6 -340.0
UBC -640.0
POLD1 -744.0
CCNE1 -881.0
CCNA1 -892.0
PSMD13 -1223.0
H2BC12 -1288.0
MCM10 -1298.0
H2AZ1 -1561.0
CDC7 -1658.0
CDC45 -1753.0
POLE -2012.0
GINS3 -2028.0
H2BC4 -2033.0
H3C10 -2100.0
RFC3 -2132.0
GMNN -2214.0
PSME3 -2265.0
RPA1 -2286.0
H4C13 -2348.0
CUL1 -2716.0
H4C12 -2774.0
UBE2C -2846.0
UBA52 -2875.0
PSMB7 -2995.0
RFC2 -3028.0
PSME4 -3042.0
ANAPC5 -3127.0
H4C9 -3283.0
H2AC6 -3373.0
KPNA1 -3430.0
CDT1 -3492.0
CCNA2 -3622.0
PSMA6 -3897.0
PSMB2 -4270.0
LIG1 -4363.0
H4C5 -4637.0
SEM1 -4777.0
H4C4 -4917.0
POLD2 -4947.0
ORC3 -4974.0
PSMD8 -5041.0
H2AX -5114.0
ANAPC15 -5225.0
PSMF1 -5472.0
POLD3 -5644.0
H2BC11 -5816.0
PSMD6 -5971.0
MCM7 -6234.0
H2BC26 -6669.0
PSMB6 -6874.0
ORC5 -6898.0
UBE2D1 -7157.0
FZR1 -7345.0
H2BC1 -7617.0
PSME1 -8232.0
RFC1 -8464.0
PSMB11 -9151.0
ANAPC2 -9497.0
POLE4 -9664.0



REACTOME_M_PHASE

REACTOME_M_PHASE
1096
set REACTOME_M_PHASE
setSize 398
pANOVA 8e-08
s.dist 0.157
p.adjustANOVA 6.26e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C12 10715
MZT2B 10707
TUBB8 10699
H2BC14 10635
H2AC14 10619
TUBB4B 10590
MZT2A 10501
H2BC6 10447
H2BC17 10375
DYNLL2 10298
H4C1 10268
H2AC4 10244
SET 10185
H3C1 10183
H3C6 9987
MAPRE1 9923
KIF2A 9896
PSMB8 9883
KNL1 9842
HAUS8 9829

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C12 10715.0
MZT2B 10707.0
TUBB8 10699.0
H2BC14 10635.0
H2AC14 10619.0
TUBB4B 10590.0
MZT2A 10501.0
H2BC6 10447.0
H2BC17 10375.0
DYNLL2 10298.0
H4C1 10268.0
H2AC4 10244.0
SET 10185.0
H3C1 10183.0
H3C6 9987.0
MAPRE1 9923.0
KIF2A 9896.0
PSMB8 9883.0
KNL1 9842.0
HAUS8 9829.0
TUBG2 9780.0
UBE2S 9716.0
HAUS1 9712.0
H3C2 9609.0
PSMC1 9440.0
MAD2L1 9381.0
CSNK2A1 9373.0
H3C8 9237.0
H2AJ 9219.0
CDC26 9208.0
NDEL1 8967.0
H4C3 8934.0
CEP70 8931.0
TUBB 8793.0
H4C8 8774.0
H2AC20 8751.0
ZWINT 8650.0
PSMD4 8637.0
NEK6 8585.0
CTDNEP1 8574.0
TUBA4B 8566.0
PSME2 8563.0
CENPM 8454.0
PSMD7 8416.0
TUBB2B 8395.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0
NEDD1 8330.0
TUBA4A 8265.0
PSMB3 8251.0
TUBG1 8218.0
KIF23 8212.0
SIRT2 8159.0
NUP153 8090.0
NSL1 8084.0
H2BC9 7978.5
H3C7 7978.5
SPC24 7943.0
EML4 7914.0
NUP58 7912.0
PSMC6 7899.0
RB1 7836.0
H2BC21 7828.0
ANAPC11 7732.0
BLZF1 7723.0
RPS27A 7698.0
XPO1 7679.0
CENPE 7598.0
H2AC18 7550.5
H2AC19 7550.5
PLK1 7394.0
CDK1 7383.0
RAB1A 7357.0
UBB 7319.0
H3C4 7298.0
CENPA 7291.0
HAUS2 7249.0
TUBA1B 7189.0
PAFAH1B1 7087.0
PSMC3 7021.0
TUBB4A 7002.0
PPP2R1A 6985.0
CEP135 6981.0
ACTR1A 6970.0
PSMB9 6881.0
MASTL 6854.0
NUMA1 6844.0
H2BC3 6830.0
RAN 6824.0
PSMA2 6802.0
CHMP2B 6689.0
PDS5A 6676.0
CDC16 6674.0
H2BC5 6618.0
LPIN2 6562.0
CEP57 6518.0
H2AZ2 6467.0
NDC80 6455.0
AURKB 6374.0
HAUS4 6371.0
ANAPC16 6333.0
PCM1 6298.0
NUP214 6207.0
NUP88 6185.0
NUP160 6067.0
H2BC10 6026.0
KPNB1 5988.0
SPC25 5934.0
PSMD12 5909.0
CHMP7 5849.0
ALMS1 5848.0
PSMA3 5797.0
PSMC2 5730.0
MIS12 5708.0
PSMA1 5699.0
SKA1 5694.0
RAB1B 5659.0
PMF1 5583.0
FBXO5 5571.0
RANBP2 5556.0
NUP62 5513.0
PSMB4 5511.0
NUP35 5491.0
CENPK 5486.0
PSMA7 5457.0
NUP107 5390.0
PRKACA 5275.0
PSMC5 5252.0
SEH1L 5251.0
CNEP1R1 5217.0
H3C11 5197.0
PPP2R5A 5135.0
CDC20 5122.0
HSP90AA1 4971.0
PSMA4 4968.0
CEP152 4952.0
KIF18A 4930.0
ENSA 4929.0
VRK2 4791.0
NEK2 4725.0
CHMP3 4700.0
LPIN3 4666.0
AKAP9 4591.0
NCAPD2 4587.0
BUB1B 4566.0
H2BC15 4475.0
SKA2 4335.0
PPP2R5B 4283.0
NUP37 4196.0
PSMD3 4188.0
CSNK2A2 4101.0
ARPP19 4058.0
DYNC1LI2 4052.0
CEP43 3999.0
SGO1 3934.0
CDC23 3912.0
CENPL 3837.0
ANAPC10 3818.0
TUBB6 3809.0
YWHAG 3771.0
CEP250 3700.0
NUP54 3624.0
TNPO1 3598.0
NUP85 3458.0
PSMC4 3370.0
USO1 3354.0
NUP50 3335.0
TAOK1 3289.0
RAB2A 3281.0
PTTG1 3278.0
DSN1 3269.0
PSMD1 3237.0
GORASP2 3216.0
H2BC8 3188.0
KIF20A 3180.0
NUF2 3136.0
CENPT 3121.0
CDCA8 3106.0
CENPC 3064.0
H2AC8 3039.0
PPP2R5E 3022.0
MZT1 2913.0
NUP133 2881.0
ANAPC4 2868.0
PPP2R5D 2818.0
PSMD5 2770.0
B9D2 2744.0
ANAPC1 2721.0
CENPS 2624.0
TUBA1A 2579.0
CSNK2B 2449.0
H4C16 2382.0
SPDL1 2374.0
H3C3 2303.0
HAUS5 2273.0
AAAS 2175.0
KNTC1 2148.0
PSMB10 2137.0
CCNB2 2044.0
PDS5B 1874.0
PSMB1 1698.0
DYNLL1 1562.0
CHMP4B 1329.0
H4C2 1279.0
PSMA8 1258.0
CEP63 1246.0
PPP2CB 1242.0
PSMD2 1209.0
ANKLE2 1152.0
YWHAE 1143.0
RPS27 1132.0
LEMD3 1122.0
H4C11 1080.0
PSMD9 1039.0
CENPH 938.0
CEP41 851.0
CEP192 843.0
H2BC13 823.0
PSMD14 794.0
TUBGCP3 773.0
NEK9 771.0
CHMP4A 698.0
RCC1 663.0
ZW10 644.0
PLK4 535.0
CENPO 442.0
CLASP2 412.0
PSMD11 411.0
PSMA5 410.0
HAUS3 272.0
CCP110 260.0
ZWILCH 197.0
NUDC 91.0
CDC27 89.0
ANAPC7 43.0
NDC1 28.0
NUP155 -40.0
PPP2CA -89.0
PSMB5 -134.0
DYNC1LI1 -141.0
TUBB3 -261.0
CENPN -305.0
UBE2E1 -331.0
H4C6 -340.0
ODF2 -460.0
NCAPD3 -467.0
WAPL -534.0
NDE1 -565.0
TUBB1 -568.0
CCNB1 -600.0
BUB1 -631.0
UBC -640.0
SPAST -691.0
NEK7 -729.0
TUBGCP4 -808.0
AHCTF1 -1001.0
PPP2R2A -1010.0
CEP290 -1045.0
PSMD13 -1223.0
VRK1 -1255.0
LBR -1269.0
H2BC12 -1288.0
TPR -1291.0
PPP2R5C -1316.0
VPS4A -1338.0
NUP98 -1370.0
SMC4 -1405.0
NUP42 -1491.0
BUB3 -1503.0
H2AZ1 -1561.0
CENPQ -1771.0
PPP1CC -1773.0
NUP93 -1778.0
PCNT -1854.0
PRKCB -1916.0
H2BC4 -2033.0
IST1 -2089.0
H3C10 -2100.0
DCTN1 -2108.0
CDK5RAP2 -2164.0
PSME3 -2265.0
GORASP1 -2269.0
H4C13 -2348.0
STAG1 -2377.0
CEP164 -2410.0
RCC2 -2441.0
CKAP5 -2537.0
NUP188 -2578.0
CENPP -2623.0
NME7 -2681.0
KIF2C -2754.0
NCAPG -2760.0
DYNC1I2 -2769.0
H4C12 -2774.0
UBE2C -2846.0
UBA52 -2875.0
PSMB7 -2995.0
NIPBL -3006.0
SMC2 -3038.0
PSME4 -3042.0
NINL -3062.0
CEP76 -3070.0
SUMO1 -3074.0
CDCA5 -3126.0
ANAPC5 -3127.0
KMT5A -3229.0
H4C9 -3283.0
NCAPG2 -3295.0
BANF1 -3329.0
H2AC6 -3373.0
PRKCA -3379.0
CEP78 -3450.0
SFI1 -3491.0
NUP205 -3512.0
INCENP -3590.0
CC2D1B -3711.0
ITGB3BP -3785.0
CHMP2A -3819.0
PSMA6 -3897.0
CLASP1 -3976.0
PSMB2 -4270.0
CENPF -4488.0
LPIN1 -4510.0
TUBA8 -4516.0
SSNA1 -4575.0
TUBA1C -4583.0
NUP210 -4632.0
H4C5 -4637.0
SGO2 -4765.0
SEM1 -4777.0
SEC13 -4820.0
H4C4 -4917.0
NCAPH -5011.0
PSMD8 -5041.0
H2AX -5114.0
DCTN3 -5120.0
RAD21 -5203.0
ANAPC15 -5225.0
HAUS6 -5265.0
TMPO -5365.0
PSMF1 -5472.0
SDCCAG8 -5620.0
TUBB2A -5696.0
MAD1L1 -5791.0
H2BC11 -5816.0
SMC3 -5831.0
LEMD2 -5864.0
NCAPH2 -5925.0
LMNB1 -5936.0
PSMD6 -5971.0
NUP43 -6011.0
TUBGCP5 -6056.0
TUBGCP6 -6161.0
CENPU -6237.0
DYNC1H1 -6369.0
GOLGA2 -6534.0
POM121 -6621.0
H2BC26 -6669.0
CEP131 -6715.0
LMNA -6719.0
MAPK1 -6741.0
H3-4 -6761.0
PSMB6 -6874.0
CLIP1 -7030.0
CEP72 -7082.0
MCPH1 -7094.0
PRKAR2B -7133.0
UBE2D1 -7157.0
RAE1 -7253.0
MAPK3 -7453.0
TUBGCP2 -7550.0
H2BC1 -7617.0
POM121C -7658.0
CENPJ -7669.0
DYNC1I1 -7779.0
PPP2R2D -7813.0
CSNK1D -8034.0
CNTRL -8064.0
PSME1 -8232.0
UBE2I -8350.0
MAU2 -8421.0
DCTN2 -8430.0
PPP2R1B -8545.0
BIRC5 -8677.0
CHMP4C -8782.0
CHMP6 -8868.0
PSMB11 -9151.0
RANGAP1 -9421.0
ANAPC2 -9497.0
TUBA3C -9626.0
ESPL1 -9689.0
CSNK1E -9776.0
TUBAL3 -9995.0
KIF2B -10643.0
TUBA3D -10657.0
TUBA3E -11051.0



REACTOME_CELLULAR_RESPONSE_TO_STARVATION

REACTOME_CELLULAR_RESPONSE_TO_STARVATION
1582
set REACTOME_CELLULAR_RESPONSE_TO_STARVATION
setSize 147
pANOVA 1.01e-07
s.dist 0.254
p.adjustANOVA 7.51e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS5 10401
KPTN 10376
LAMTOR5 10174
ATP6V0C 10039
RPL39L 10015
RPS13 10010
RPLP0 9720
EIF2S2 9447
RPL27 9406
RPL6 9269
ATF4 9235
RPL27A 8979
RPS28 8978
RPS8 8920
ATP6V0E1 8919
ATP6V1F 8870
RPS12 8794
RPS25 8638
RPL19 8597
RPL9 8592

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS5 10401.0
KPTN 10376.0
LAMTOR5 10174.0
ATP6V0C 10039.0
RPL39L 10015.0
RPS13 10010.0
RPLP0 9720.0
EIF2S2 9447.0
RPL27 9406.0
RPL6 9269.0
ATF4 9235.0
RPL27A 8979.0
RPS28 8978.0
RPS8 8920.0
ATP6V0E1 8919.0
ATP6V1F 8870.0
RPS12 8794.0
RPS25 8638.0
RPL19 8597.0
RPL9 8592.0
RPL12 8542.0
RPS6 8501.0
ATP6V1G1 8473.0
RPL41 8240.0
RPL18 8234.0
RPL10A 8175.0
RPS2 8109.0
FAU 8086.0
CASTOR1 8069.0
RPL5 8055.0
RPL36AL 8033.5
RPS3A 7941.0
RPL23 7907.0
RPS18 7868.0
CEBPB 7763.0
LAMTOR2 7721.0
RPL13 7712.0
RPS27A 7698.0
RPL13A 7489.5
ATF2 7405.0
RPLP2 7348.0
RPL3 7194.0
BMT2 7163.0
RPL4 7148.0
RPS26 6957.0
RPL38 6914.0
RPS21 6901.0
RPL35A 6893.0
RPL21 6804.0
EIF2S1 6710.0
ATP6V1G2 6585.0
LAMTOR4 6497.0
RPL28 6441.0
TRIB3 6151.0
RPL34 6124.0
RRAGC 6100.0
RPL7 6080.0
RPL17 6034.0
ATP6V1C1 6032.0
ATP6V1E1 6001.0
ATP6V1B1 5902.0
RPS29 5882.0
RPS15 5697.0
DDIT3 5545.0
RPL18A 5467.0
RPL32 5357.0
SEH1L 5251.0
RPS15A 5210.0
RPS10 5051.0
RPS19 5043.0
ATP6V1A 5003.0
RPL35 4765.0
RPS20 4727.0
WDR59 4304.0
ATP6V1D 3847.0
CEBPG 3796.0
RPSA 3658.0
RPL26L1 3215.0
ATP6V1H 3174.0
RPL8 3119.0
ATF3 3009.0
EIF2AK4 2874.0
RPS24 2748.0
RPL30 2631.0
RPL37 2527.0
RPS16 2475.0
RPL11 2329.0
RPS27L 2308.0
ATP6V0E2 2205.0
RPS23 2004.0
RPL36 1365.0
KICS2 1359.0
RPS11 1269.0
ASNS 1195.0
RPS27 1132.0
NPRL2 907.0
RPLP1 792.0
FNIP1 680.0
SESN1 639.0
RPL22 440.0
RPS14 322.0
RPL24 57.0
MIOS 56.0
SESN2 31.0
RPL14 -57.0
RPS3 -850.0
ATP6V1B2 -999.0
RPL23A -1287.0
TCIRG1 -1360.0
RPL15 -1589.0
ATP6V1C2 -1710.0
SH3BP4 -1751.0
LAMTOR3 -1769.0
FNIP2 -1921.0
RPS9 -1972.0
RRAGD -2541.0
UBA52 -2875.0
RPS7 -3608.0
RPTOR -3900.0
MLST8 -4487.0
RPL3L -4519.0
RRAGA -4638.0
RPL29 -4767.0
SEC13 -4820.0
IMPACT -4922.0
MTOR -5272.0
ATP6V1G3 -5643.0
RPL37A -5673.0
RPL7A -5783.0
SZT2 -5917.0
ATP6V0D2 -6012.0
RPL22L1 -6323.0
ATP6V0D1 -6451.0
ATP6V0B -6755.0
RPL26 -6909.0
SLC38A9 -7574.0
DEPDC5 -8029.0
ATP6V1E2 -8031.0
RHEB -8364.0
FLCN -8451.0
GCN1 -8547.0
RPL31 -8668.0
NPRL3 -8786.0
ITFG2 -8951.0
WDR24 -9433.0
LAMTOR1 -9552.0
RPL10L -10702.0



REACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION

REACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION
852
set REACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION
setSize 84
pANOVA 1.12e-07
s.dist 0.335
p.adjustANOVA 7.82e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C12 10715
H2BC14 10635
H2AC14 10619
H2BC6 10447
H2BC17 10375
H4C1 10268
H2AC4 10244
H3C1 10183
ACTB 10161
H3C6 9987
H3C2 9609
POLR1H 9366
BAZ1B 9264
POLR2K 9241
H3C8 9237
H2AJ 9219
SMARCA5 9103
H4C3 8934
H4C8 8774
H2AC20 8751

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
H4C1 10268.0
H2AC4 10244.0
H3C1 10183.0
ACTB 10161.0
H3C6 9987.0
H3C2 9609.0
POLR1H 9366.0
BAZ1B 9264.0
POLR2K 9241.0
H3C8 9237.0
H2AJ 9219.0
SMARCA5 9103.0
H4C3 8934.0
H4C8 8774.0
H2AC20 8751.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0
H2BC9 7978.5
H3C7 7978.5
H2BC21 7828.0
POLR1E 7682.0
H2AC18 7550.5
H2AC19 7550.5
H3C4 7298.0
TAF1A 7141.0
H2BC3 6830.0
MYO1C 6734.0
H2BC5 6618.0
H2AZ2 6467.0
POLR1G 6379.0
H2BC10 6026.0
TAF1B 5541.0
DDX21 5401.0
H3C11 5197.0
POLR2H 4937.0
H2BC15 4475.0
TBP 3926.0
H2BC8 3188.0
POLR1D 3137.0
H2AC8 3039.0
POLR1A 2598.0
H4C16 2382.0
POLR1B 2328.0
H3C3 2303.0
GSK3B 2248.0
KAT2B 1876.0
POLR2E 1875.0
ERCC6 1693.0
H4C2 1279.0
H4C11 1080.0
H2BC13 823.0
SF3B1 782.0
TAF1D 291.0
H4C6 -340.0
EP300 -1043.0
H2BC12 -1288.0
TAF1C -1359.0
H2AZ1 -1561.0
H2BC4 -2033.0
H3C10 -2100.0
KAT2A -2329.0
H4C13 -2348.0
H4C12 -2774.0
H4C9 -3283.0
H2AC6 -3373.0
POLR2F -3844.0
MYBBP1A -4307.0
POLR2L -4399.0
POLR1C -4599.0
H4C5 -4637.0
H4C4 -4917.0
H2AX -5114.0
H2BC11 -5816.0
H2BC26 -6669.0
H2BC1 -7617.0
DEK -8516.0
POLR1F -9054.0



REACTOME_MITOCHONDRIAL_TRANSLATION

REACTOME_MITOCHONDRIAL_TRANSLATION
874
set REACTOME_MITOCHONDRIAL_TRANSLATION
setSize 93
pANOVA 1.14e-07
s.dist 0.318
p.adjustANOVA 7.82e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
MRPS16 10267
MRPS15 10106
MRPS18C 9864
MRPL40 9831
MRPL57 9674
MRPL45 9575
MRPL27 9482
MRPL51 9470
CHCHD1 9428
MRPL33 8988
MRPL50 8956
ERAL1 8946
MRPS34 8726
MRPS31 8545
MRPL10 8526
MRPS11 8467
MRPS18A 8321
MRPL52 8254
MRPL15 8129
MRPL30 8025

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MRPS16 10267
MRPS15 10106
MRPS18C 9864
MRPL40 9831
MRPL57 9674
MRPL45 9575
MRPL27 9482
MRPL51 9470
CHCHD1 9428
MRPL33 8988
MRPL50 8956
ERAL1 8946
MRPS34 8726
MRPS31 8545
MRPL10 8526
MRPS11 8467
MRPS18A 8321
MRPL52 8254
MRPL15 8129
MRPL30 8025
MRPL18 7849
MRPL21 7755
MRPL37 7455
MRPL9 7355
MRPL19 7317
MRPL16 7117
MRPS26 6980
MRPL12 6935
MRPL32 6927
MRPL20 6879
MRPL49 6703
MRPS10 6450
MRPL35 6416
MRPL48 6415
MRPS17 6357
MRPL54 5881
MRPL46 5570
MRPS30 5496
MRPL55 5291
MRPL44 5222
MRPL36 5209
MTIF3 5144
MRPS12 5101
MRPL17 5006
MTFMT 4980
MRPL2 4788
MRPL53 4711
MRPL28 4456
DAP3 4302
PTCD3 3897
MRPL11 3868
MTRF1L 3823
GADD45GIP1 3027
MRPS25 2898
MRPL14 2494
MRPS33 2362
MRPL4 2084
MTIF2 1648
TUFM 1634
AURKAIP1 1591
MRPS7 1442
MRPL34 1274
MRRF 842
MRPL24 298
MRPL58 257
MRPS2 88
MRPS21 2
MRPS23 -144
TSFM -410
MRPS18B -501
GFM2 -526
MRPS27 -566
MRPL3 -733
MRPL13 -785
MRPL23 -968
MRPS6 -1267
MRPS24 -1734
MRPS28 -1788
OXA1L -2311
MRPL38 -2784
MRPS9 -3140
GFM1 -3152
MRPS14 -3285
MRPS35 -3288
MRPL41 -4066
MRPL1 -4197
MRPL43 -5642
MRPS22 -5652
MRPL39 -6253
MRPL42 -6569
MRPS5 -6791
MRPL22 -6978
MRPL47 -7519



REACTOME_SIGNALING_BY_ROBO_RECEPTORS

REACTOME_SIGNALING_BY_ROBO_RECEPTORS
605
set REACTOME_SIGNALING_BY_ROBO_RECEPTORS
setSize 206
pANOVA 1.92e-07
s.dist 0.21
p.adjustANOVA 1.26e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS5 10401
CXCR4 10063
LDB1 10030
RPL39L 10015
RPS13 10010
PFN1 9999
PSMB8 9883
RPLP0 9720
HOXA2 9480
PSMC1 9440
RPL27 9406
RPL6 9269
CAP2 9198
RBM8A 9140
RPL27A 8979
RPS28 8978
RPS8 8920
RBX1 8801
RPS12 8794
PRKACB 8775

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS5 10401.0
CXCR4 10063.0
LDB1 10030.0
RPL39L 10015.0
RPS13 10010.0
PFN1 9999.0
PSMB8 9883.0
RPLP0 9720.0
HOXA2 9480.0
PSMC1 9440.0
RPL27 9406.0
RPL6 9269.0
CAP2 9198.0
RBM8A 9140.0
RPL27A 8979.0
RPS28 8978.0
RPS8 8920.0
RBX1 8801.0
RPS12 8794.0
PRKACB 8775.0
RPS25 8638.0
PSMD4 8637.0
RPL19 8597.0
RPL9 8592.0
PSME2 8563.0
RPL12 8542.0
RPS6 8501.0
LHX9 8452.0
PSMD7 8416.0
PSMB3 8251.0
RPL41 8240.0
RPL18 8234.0
RPL10A 8175.0
LHX2 8124.0
RPS2 8109.0
FAU 8086.0
RPL5 8055.0
RPL36AL 8033.5
FLRT3 7971.0
RPS3A 7941.0
RPL23 7907.0
PSMC6 7899.0
RPS18 7868.0
RPL13 7712.0
RPS27A 7698.0
RPL13A 7489.5
RPLP2 7348.0
UBB 7319.0
RPL3 7194.0
RPL4 7148.0
VASP 7126.0
PSMC3 7021.0
RPS26 6957.0
RPL38 6914.0
RPS21 6901.0
RPL35A 6893.0
PSMB9 6881.0
RPL21 6804.0
PSMA2 6802.0
RPL28 6441.0
USP33 6240.0
RPL34 6124.0
RPL7 6080.0
RPL17 6034.0
PSMD12 5909.0
RPS29 5882.0
PSMA3 5797.0
PSMC2 5730.0
PSMA1 5699.0
RPS15 5697.0
LHX4 5566.0
PSMB4 5511.0
NCK2 5489.0
RPL18A 5467.0
PSMA7 5457.0
RPL32 5357.0
PPP3CB 5331.0
PRKACA 5275.0
PSMC5 5252.0
RPS15A 5210.0
RPS10 5051.0
RPS19 5043.0
PSMA4 4968.0
PFN2 4863.0
RPL35 4765.0
NELL2 4739.0
RPS20 4727.0
NCBP2 4667.0
GSPT1 4602.0
ELOC 4336.0
PSMD3 4188.0
RPSA 3658.0
UPF3A 3657.0
ELOB 3538.0
UPF2 3441.0
PSMC4 3370.0
PSMD1 3237.0
RPL26L1 3215.0
RPL8 3119.0
PSMD5 2770.0
RPS24 2748.0
CAP1 2670.0
RPL30 2631.0
CXCL12 2545.0
RPL37 2527.0
RPS16 2475.0
MAGOHB 2447.0
RPL11 2329.0
RPS27L 2308.0
PSMB10 2137.0
RPS23 2004.0
PSMB1 1698.0
RPL36 1365.0
MAGOH 1349.0
RPS11 1269.0
PSMA8 1258.0
PSMD2 1209.0
RPS27 1132.0
PSMD9 1039.0
SRGAP3 992.0
PSMD14 794.0
RPLP1 792.0
ETF1 594.0
MSI1 533.0
RPL22 440.0
CLASP2 412.0
PSMD11 411.0
PSMA5 410.0
GPC1 381.0
RPS14 322.0
SOS1 312.0
RPL24 57.0
ROBO3 -12.0
RPL14 -57.0
PSMB5 -134.0
DCC -174.0
PRKAR2A -232.0
PAK1 -345.0
UBC -640.0
NRP1 -788.0
RPS3 -850.0
EIF4A3 -993.0
SOS2 -996.0
EVL -1009.0
PSMD13 -1223.0
RPL23A -1287.0
PAK6 -1311.0
CUL2 -1490.0
PAK5 -1558.0
RPL15 -1589.0
CDC42 -1927.0
RPS9 -1972.0
ENAH -2264.0
PSME3 -2265.0
ARHGAP39 -2471.0
RAC1 -2540.0
NTN1 -2559.0
EIF4G1 -2605.0
ISL1 -2615.0
SLIT3 -2820.0
PAK4 -2822.0
UBA52 -2875.0
PSMB7 -2995.0
PSME4 -3042.0
NCBP1 -3261.0
NCK1 -3321.0
PRKCA -3379.0
SRC -3509.0
RPS7 -3608.0
ZSWIM8 -3783.0
ABL2 -3870.0
AKAP5 -3883.0
PSMA6 -3897.0
CLASP1 -3976.0
PSMB2 -4270.0
PAK2 -4482.0
RPL3L -4519.0
RPL29 -4767.0
SEM1 -4777.0
ABL1 -4874.0
LHX3 -4931.0
PSMD8 -5041.0
RHOA -5156.0
MYO9B -5443.0
PSMF1 -5472.0
RPL37A -5673.0
SLIT2 -5703.0
RPL7A -5783.0
PSMD6 -5971.0
PABPC1 -5994.0
ROBO1 -6102.0
SLIT1 -6188.0
RPL22L1 -6323.0
RNPS1 -6758.0
PSMB6 -6874.0
RPL26 -6909.0
CASC3 -7100.0
SRGAP1 -7126.0
DAG1 -7956.0
PSME1 -8232.0
RPL31 -8668.0
ROBO2 -8739.0
PSMB11 -9151.0
SRGAP2 -10049.0
PRKACG -10206.0
RPL10L -10702.0



REACTOME_MEIOTIC_RECOMBINATION

REACTOME_MEIOTIC_RECOMBINATION
1433
set REACTOME_MEIOTIC_RECOMBINATION
setSize 80
pANOVA 2.02e-07
s.dist 0.336
p.adjustANOVA 1.27e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
TEX15 10319.0
H4C1 10268.0
H2AC4 10244.0
H3C1 10183.0
H3C6 9987.0
H3C2 9609.0
CDK4 9521.0
H3C8 9237.0
H2AJ 9219.0
H4C3 8934.0
H4C8 8774.0
H2AC20 8751.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
TEX15 10319.0
H4C1 10268.0
H2AC4 10244.0
H3C1 10183.0
H3C6 9987.0
H3C2 9609.0
CDK4 9521.0
H3C8 9237.0
H2AJ 9219.0
H4C3 8934.0
H4C8 8774.0
H2AC20 8751.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0
DMC1 8244.0
H2BC9 7978.5
H3C7 7978.5
H2BC21 7828.0
NBN 7592.0
H2AC18 7550.5
H2AC19 7550.5
RAD51C 7333.0
H3C4 7298.0
MSH4 7028.0
H2BC3 6830.0
H2BC5 6618.0
H2AZ2 6467.0
H2BC10 6026.0
H3C11 5197.0
MLH3 4821.0
ATM 4677.0
RAD51 4665.0
H2BC15 4475.0
RAD50 3962.0
CDK2 3557.0
RPA3 3368.0
H2BC8 3188.0
H2AC8 3039.0
H4C16 2382.0
H3C3 2303.0
PRDM9 2240.0
BRCA1 2223.0
TOP3A 1628.0
SPO11 1530.0
RPA2 1446.0
MRE11 1313.0
H4C2 1279.0
H4C11 1080.0
H2BC13 823.0
PSMC3IP -241.0
H4C6 -340.0
MND1 -1216.0
MLH1 -1249.0
H2BC12 -1288.0
RBBP8 -1495.0
H2AZ1 -1561.0
H2BC4 -2033.0
H3C10 -2100.0
RPA1 -2286.0
H4C13 -2348.0
H4C12 -2774.0
BRCA2 -2863.0
H4C9 -3283.0
H2AC6 -3373.0
H4C5 -4637.0
H4C4 -4917.0
BLM -5013.0
MSH5 -5061.0
H2AX -5114.0
H2BC11 -5816.0
H2BC26 -6669.0
H3-4 -6761.0
H2BC1 -7617.0



REACTOME_SIRT1_NEGATIVELY_REGULATES_RRNA_EXPRESSION

REACTOME_SIRT1_NEGATIVELY_REGULATES_RRNA_EXPRESSION
737
set REACTOME_SIRT1_NEGATIVELY_REGULATES_RRNA_EXPRESSION
setSize 60
pANOVA 2.39e-07
s.dist 0.386
p.adjustANOVA 1.45e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
H4C1 10268.0
H2AC4 10244.0
H3C1 10183.0
H3C6 9987.0
H3C2 9609.0
H3C8 9237.0
H2AJ 9219.0
H4C3 8934.0
H4C8 8774.0
H2AC20 8751.0
RRP8 8525.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
H4C1 10268.0
H2AC4 10244.0
H3C1 10183.0
H3C6 9987.0
H3C2 9609.0
H3C8 9237.0
H2AJ 9219.0
H4C3 8934.0
H4C8 8774.0
H2AC20 8751.0
RRP8 8525.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0
H2BC9 7978.5
H3C7 7978.5
H2BC21 7828.0
H2AC18 7550.5
H2AC19 7550.5
H3C4 7298.0
TAF1A 7141.0
H2BC3 6830.0
H2BC5 6618.0
H2AZ2 6467.0
H2BC10 6026.0
TAF1B 5541.0
H3C11 5197.0
H2BC15 4475.0
TBP 3926.0
H2BC8 3188.0
H2AC8 3039.0
H4C16 2382.0
H3C3 2303.0
H4C2 1279.0
H4C11 1080.0
H2BC13 823.0
TAF1D 291.0
H4C6 -340.0
H2BC12 -1288.0
TAF1C -1359.0
H2AZ1 -1561.0
H2BC4 -2033.0
H3C10 -2100.0
H4C13 -2348.0
SIRT1 -2694.0
H4C12 -2774.0
H4C9 -3283.0
H2AC6 -3373.0
H4C5 -4637.0
H4C4 -4917.0
H2AX -5114.0
H2BC11 -5816.0
H2BC26 -6669.0
H2BC1 -7617.0



REACTOME_CELL_CYCLE_CHECKPOINTS

REACTOME_CELL_CYCLE_CHECKPOINTS
1120
set REACTOME_CELL_CYCLE_CHECKPOINTS
setSize 284
pANOVA 2.7e-07
s.dist 0.177
p.adjustANOVA 1.58e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 10635
H2BC6 10447
H2BC17 10375
DYNLL2 10298
H4C1 10268
MAPRE1 9923
KIF2A 9896
PSMB8 9883
KNL1 9842
UBE2S 9716
YWHAH 9707
PSMC1 9440
MAD2L1 9381
RAD1 9369
CDC26 9208
MDM2 9066
NDEL1 8967
H4C3 8934
H4C8 8774
ZWINT 8650

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 10635.0
H2BC6 10447.0
H2BC17 10375.0
DYNLL2 10298.0
H4C1 10268.0
MAPRE1 9923.0
KIF2A 9896.0
PSMB8 9883.0
KNL1 9842.0
UBE2S 9716.0
YWHAH 9707.0
PSMC1 9440.0
MAD2L1 9381.0
RAD1 9369.0
CDC26 9208.0
MDM2 9066.0
NDEL1 8967.0
H4C3 8934.0
H4C8 8774.0
ZWINT 8650.0
PSMD4 8637.0
PSME2 8563.0
CENPM 8454.0
PSMD7 8416.0
H2BC7 8363.5
RAD17 8341.0
TP53 8272.0
PSMB3 8251.0
MCM5 8147.0
ORC6 8118.0
NSL1 8084.0
H2BC9 7978.5
SPC24 7943.0
PSMC6 7899.0
H2BC21 7828.0
ANAPC11 7732.0
TP53BP1 7725.0
RPS27A 7698.0
XPO1 7679.0
ZNF385A 7669.0
CENPE 7598.0
NBN 7592.0
CHEK1 7547.0
CDC25C 7483.0
GTSE1 7452.0
PLK1 7394.0
CDK1 7383.0
UBB 7319.0
CENPA 7291.0
PAFAH1B1 7087.0
ORC4 7082.0
PSMC3 7021.0
PPP2R1A 6985.0
PSMB9 6881.0
H2BC3 6830.0
ABRAXAS1 6811.0
PSMA2 6802.0
MDC1 6793.0
YWHAB 6683.0
CDC16 6674.0
MCM3 6656.0
H2BC5 6618.0
MDM4 6604.0
NDC80 6455.0
AURKB 6374.0
ANAPC16 6333.0
NUP160 6067.0
H2BC10 6026.0
YWHAZ 5941.0
SPC25 5934.0
PSMD12 5909.0
DNA2 5890.0
PSMA3 5797.0
PSMC2 5730.0
MIS12 5708.0
PSMA1 5699.0
SKA1 5694.0
PMF1 5583.0
RANBP2 5556.0
PSMB4 5511.0
CENPK 5486.0
PSMA7 5457.0
EXO1 5408.0
NUP107 5390.0
PSMC5 5252.0
SEH1L 5251.0
PPP2R5A 5135.0
CDC20 5122.0
ATR 5120.0
CHEK2 5061.0
PSMA4 4968.0
KIF18A 4930.0
RAD9B 4864.0
RFC5 4755.0
ATM 4677.0
BUB1B 4566.0
ORC2 4544.0
H2BC15 4475.0
WRN 4437.0
SKA2 4335.0
ORC1 4331.0
PPP2R5B 4283.0
NUP37 4196.0
PSMD3 4188.0
DYNC1LI2 4052.0
WEE1 4032.0
RFC4 3986.0
RAD50 3962.0
SGO1 3934.0
CDC23 3912.0
BARD1 3901.0
COP1 3872.0
CDC6 3859.0
CENPL 3837.0
ANAPC10 3818.0
YWHAG 3771.0
MCM2 3608.0
CDK2 3557.0
NUP85 3458.0
PSMC4 3370.0
RPA3 3368.0
TAOK1 3289.0
DSN1 3269.0
RHNO1 3243.0
PSMD1 3237.0
H2BC8 3188.0
CLSPN 3142.0
NUF2 3136.0
CENPT 3121.0
CDCA8 3106.0
CENPC 3064.0
PPP2R5E 3022.0
MCM6 2968.0
CDKN2A 2953.0
NUP133 2881.0
ANAPC4 2868.0
PPP2R5D 2818.0
PSMD5 2770.0
B9D2 2744.0
ANAPC1 2721.0
HUS1 2686.0
CENPS 2624.0
H4C16 2382.0
SPDL1 2374.0
BRCA1 2223.0
KNTC1 2148.0
PSMB10 2137.0
BABAM1 2098.0
CCNB2 2044.0
DBF4 1773.0
RMI1 1759.0
RNF168 1715.0
PSMB1 1698.0
TOP3A 1628.0
DYNLL1 1562.0
RPA2 1446.0
MRE11 1313.0
H4C2 1279.0
PSMA8 1258.0
PPP2CB 1242.0
PSMD2 1209.0
YWHAE 1143.0
RPS27 1132.0
H4C11 1080.0
PSMD9 1039.0
MCM4 954.0
CENPH 938.0
H2BC13 823.0
PSMD14 794.0
MCM8 737.0
CCNE2 668.0
ZW10 644.0
KAT5 642.0
UIMC1 630.0
UBE2N 540.0
CENPO 442.0
CLASP2 412.0
PSMD11 411.0
PSMA5 410.0
ZWILCH 197.0
NUDC 91.0
CDC27 89.0
ANAPC7 43.0
PPP2CA -89.0
PSMB5 -134.0
DYNC1LI1 -141.0
CENPN -305.0
UBE2E1 -331.0
H4C6 -340.0
CDKN1B -509.0
NDE1 -565.0
CCNB1 -600.0
BUB1 -631.0
UBC -640.0
YWHAQ -694.0
CDKN1A -800.0
CCNE1 -881.0
CCNA1 -892.0
AHCTF1 -1001.0
PSMD13 -1223.0
H2BC12 -1288.0
MCM10 -1298.0
PPP2R5C -1316.0
BRIP1 -1317.0
PCBP4 -1355.0
NUP98 -1370.0
RBBP8 -1495.0
BUB3 -1503.0
CDC7 -1658.0
CDC45 -1753.0
CENPQ -1771.0
PPP1CC -1773.0
H2BC4 -2033.0
RFC3 -2132.0
PIAS4 -2245.0
PSME3 -2265.0
RPA1 -2286.0
H4C13 -2348.0
RCC2 -2441.0
CKAP5 -2537.0
CENPP -2623.0
KIF2C -2754.0
DYNC1I2 -2769.0
H4C12 -2774.0
UBE2C -2846.0
UBA52 -2875.0
PSMB7 -2995.0
RFC2 -3028.0
PSME4 -3042.0
ANAPC5 -3127.0
H4C9 -3283.0
BABAM2 -3322.0
INCENP -3590.0
CCNA2 -3622.0
ITGB3BP -3785.0
CDC25A -3836.0
PSMA6 -3897.0
SFN -3911.0
CLASP1 -3976.0
ATRIP -4017.0
PSMB2 -4270.0
CENPF -4488.0
H4C5 -4637.0
UBE2V2 -4702.0
SGO2 -4765.0
SEM1 -4777.0
SEC13 -4820.0
H4C4 -4917.0
ORC3 -4974.0
BLM -5013.0
PSMD8 -5041.0
RNF8 -5042.0
H2AX -5114.0
ANAPC15 -5225.0
PSMF1 -5472.0
MAD1L1 -5791.0
H2BC11 -5816.0
PSMD6 -5971.0
NUP43 -6011.0
MCM7 -6234.0
CENPU -6237.0
NSD2 -6354.0
DYNC1H1 -6369.0
H2BC26 -6669.0
H3-4 -6761.0
PSMB6 -6874.0
ORC5 -6898.0
TOPBP1 -6907.0
RMI2 -6927.0
CLIP1 -7030.0
UBE2D1 -7157.0
PKMYT1 -7590.0
H2BC1 -7617.0
DYNC1I1 -7779.0
PHF20 -8195.0
PSME1 -8232.0
PPP2R1B -8545.0
BIRC5 -8677.0
RAD9A -9062.0
PSMB11 -9151.0
RANGAP1 -9421.0
ANAPC2 -9497.0
HERC2 -9847.0
KIF2B -10643.0



REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION

REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION
437
set REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION
setSize 138
pANOVA 3.38e-07
s.dist 0.251
p.adjustANOVA 1.88e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C12 10715
H2BC14 10635
H2AC14 10619
H2BC6 10447
H2BC17 10375
H4C1 10268
H2AC4 10244
SAP30 10201
H3C1 10183
ACTB 10161
H3C6 9987
SAP130 9965
H3C2 9609
GTF2H3 9509
POLR1H 9366
BAZ1B 9264
POLR2K 9241
H3C8 9237
H2AJ 9219
SMARCA5 9103

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
H4C1 10268.0
H2AC4 10244.0
SAP30 10201.0
H3C1 10183.0
ACTB 10161.0
H3C6 9987.0
SAP130 9965.0
H3C2 9609.0
GTF2H3 9509.0
POLR1H 9366.0
BAZ1B 9264.0
POLR2K 9241.0
H3C8 9237.0
H2AJ 9219.0
SMARCA5 9103.0
H4C3 8934.0
SIN3A 8850.0
H4C8 8774.0
H2AC20 8751.0
RRP8 8525.0
UHRF1 8451.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0
MBD2 8291.0
H2BC9 7978.5
H3C7 7978.5
H2BC21 7828.0
TDG 7759.0
POLR1E 7682.0
TTF1 7629.0
H2AC18 7550.5
H2AC19 7550.5
H3C4 7298.0
TAF1A 7141.0
HDAC2 6890.0
H2BC3 6830.0
HDAC1 6791.0
UBTF 6759.0
MYO1C 6734.0
H2BC5 6618.0
H2AZ2 6467.0
POLR1G 6379.0
H2BC10 6026.0
PHF1 5950.0
DNMT3L 5870.0
CBX3 5646.0
TAF1B 5541.0
DDX21 5401.0
H3C11 5197.0
POLR2H 4937.0
SUDS3 4716.0
SAP30BP 4705.0
H2BC15 4475.0
TBP 3926.0
MTA3 3682.0
ARID4B 3208.0
H2BC8 3188.0
POLR1D 3137.0
H2AC8 3039.0
POLR1A 2598.0
TET2 2588.0
CDK7 2530.0
H4C16 2382.0
GATAD2B 2336.0
POLR1B 2328.0
H3C3 2303.0
GSK3B 2248.0
KAT2B 1876.0
POLR2E 1875.0
SAP30L 1779.0
ERCC6 1693.0
SAP18 1491.0
H4C2 1279.0
H4C11 1080.0
MTF2 865.0
CCNH 840.0
H2BC13 823.0
ERCC2 808.0
SF3B1 782.0
TET3 593.0
DNMT3A 566.0
MBD3 347.0
TAF1D 291.0
GTF2H5 189.0
H4C6 -340.0
RBBP4 -414.0
PHF19 -620.0
CHD4 -663.0
EP300 -1043.0
SUZ12 -1050.0
CHD3 -1071.0
H2BC12 -1288.0
TAF1C -1359.0
AEBP2 -1407.0
H2AZ1 -1561.0
GTF2H1 -1760.0
H2BC4 -2033.0
H3C10 -2100.0
MTA2 -2122.0
KAT2A -2329.0
H4C13 -2348.0
EHMT2 -2398.0
SIRT1 -2694.0
H4C12 -2774.0
H4C9 -3283.0
H2AC6 -3373.0
BAZ2A -3387.0
MNAT1 -3468.0
EZH2 -3560.0
EED -3682.0
POLR2F -3844.0
GTF2H4 -4059.0
MYBBP1A -4307.0
POLR2L -4399.0
TET1 -4504.0
POLR1C -4599.0
H4C5 -4637.0
SIN3B -4783.0
DNMT1 -4856.0
H4C4 -4917.0
H2AX -5114.0
DNMT3B -5772.0
H2BC11 -5816.0
JARID2 -6252.0
H2BC26 -6669.0
H2BC1 -7617.0
DEK -8516.0
MTA1 -8549.0
GATAD2A -8692.0
POLR1F -9054.0
ERCC3 -9580.0



REACTOME_POSITIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION

REACTOME_POSITIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION
851
set REACTOME_POSITIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION
setSize 98
pANOVA 3.43e-07
s.dist 0.298
p.adjustANOVA 1.88e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C12 10715
H2BC14 10635
H2AC14 10619
H2BC6 10447
H2BC17 10375
H4C1 10268
H2AC4 10244
H3C1 10183
ACTB 10161
H3C6 9987
H3C2 9609
POLR1H 9366
BAZ1B 9264
POLR2K 9241
H3C8 9237
H2AJ 9219
SMARCA5 9103
H4C3 8934
H4C8 8774
H2AC20 8751

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
H4C1 10268.0
H2AC4 10244.0
H3C1 10183.0
ACTB 10161.0
H3C6 9987.0
H3C2 9609.0
POLR1H 9366.0
BAZ1B 9264.0
POLR2K 9241.0
H3C8 9237.0
H2AJ 9219.0
SMARCA5 9103.0
H4C3 8934.0
H4C8 8774.0
H2AC20 8751.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0
H2BC9 7978.5
H3C7 7978.5
H2BC21 7828.0
POLR1E 7682.0
TTF1 7629.0
H2AC18 7550.5
H2AC19 7550.5
H3C4 7298.0
TAF1A 7141.0
HDAC2 6890.0
H2BC3 6830.0
HDAC1 6791.0
MYO1C 6734.0
H2BC5 6618.0
H2AZ2 6467.0
POLR1G 6379.0
H2BC10 6026.0
CBX3 5646.0
TAF1B 5541.0
DDX21 5401.0
H3C11 5197.0
POLR2H 4937.0
H2BC15 4475.0
TBP 3926.0
MTA3 3682.0
H2BC8 3188.0
POLR1D 3137.0
H2AC8 3039.0
POLR1A 2598.0
H4C16 2382.0
GATAD2B 2336.0
POLR1B 2328.0
H3C3 2303.0
GSK3B 2248.0
KAT2B 1876.0
POLR2E 1875.0
ERCC6 1693.0
H4C2 1279.0
H4C11 1080.0
H2BC13 823.0
SF3B1 782.0
MBD3 347.0
TAF1D 291.0
H4C6 -340.0
RBBP4 -414.0
CHD4 -663.0
EP300 -1043.0
CHD3 -1071.0
H2BC12 -1288.0
TAF1C -1359.0
H2AZ1 -1561.0
H2BC4 -2033.0
H3C10 -2100.0
MTA2 -2122.0
KAT2A -2329.0
H4C13 -2348.0
EHMT2 -2398.0
H4C12 -2774.0
H4C9 -3283.0
H2AC6 -3373.0
POLR2F -3844.0
MYBBP1A -4307.0
POLR2L -4399.0
POLR1C -4599.0
H4C5 -4637.0
H4C4 -4917.0
H2AX -5114.0
H2BC11 -5816.0
H2BC26 -6669.0
H2BC1 -7617.0
DEK -8516.0
MTA1 -8549.0
GATAD2A -8692.0
POLR1F -9054.0



REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_HSCS

REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_HSCS
1282
set REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_HSCS
setSize 121
pANOVA 3.99e-07
s.dist 0.267
p.adjustANOVA 2.11e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C12 10715
H2BC14 10635
H2AC14 10619
H2BC6 10447
H2BC17 10375
H4C1 10268
H2AC4 10244
H3C1 10183
LDB1 10030
H3C6 9987
PSMB8 9883
H3C2 9609
PSMC1 9440
GATA3 9341
H3C8 9237
H2AJ 9219
H4C3 8934
H4C8 8774
H2AC20 8751
PSMD4 8637

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
H4C1 10268.0
H2AC4 10244.0
H3C1 10183.0
LDB1 10030.0
H3C6 9987.0
PSMB8 9883.0
H3C2 9609.0
PSMC1 9440.0
GATA3 9341.0
H3C8 9237.0
H2AJ 9219.0
H4C3 8934.0
H4C8 8774.0
H2AC20 8751.0
PSMD4 8637.0
PSME2 8563.0
PSMD7 8416.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0
PSMB3 8251.0
H2BC9 7978.5
H3C7 7978.5
PSMC6 7899.0
H2BC21 7828.0
RPS27A 7698.0
GATA2 7561.0
H2AC18 7550.5
H2AC19 7550.5
UBB 7319.0
H3C4 7298.0
PSMC3 7021.0
PSMB9 6881.0
H2BC3 6830.0
PSMA2 6802.0
H2BC5 6618.0
H2AZ2 6467.0
H2BC10 6026.0
PSMD12 5909.0
PSMA3 5797.0
KMT2A 5747.0
PSMC2 5730.0
PSMA1 5699.0
PSMB4 5511.0
PSMA7 5457.0
PSMC5 5252.0
H3C11 5197.0
PSMA4 4968.0
H2BC15 4475.0
ITCH 4318.0
YAP1 4311.0
PSMD3 4188.0
MYB 3605.0
PSMC4 3370.0
PSMD1 3237.0
H2BC8 3188.0
H2AC8 3039.0
PSMD5 2770.0
CDK7 2530.0
H4C16 2382.0
H3C3 2303.0
PSMB10 2137.0
PSMB1 1698.0
LMO2 1620.0
H4C2 1279.0
PSMA8 1258.0
PSMD2 1209.0
H4C11 1080.0
PSMD9 1039.0
CCNH 840.0
H2BC13 823.0
PSMD14 794.0
LMO1 588.0
PSMD11 411.0
PSMA5 410.0
CBFB -58.0
PSMB5 -134.0
H4C6 -340.0
UBC -640.0
PSMD13 -1223.0
H2BC12 -1288.0
H2AZ1 -1561.0
H2BC4 -2033.0
TCF3 -2071.0
H3C10 -2100.0
PSME3 -2265.0
H4C13 -2348.0
TCF12 -2729.0
H4C12 -2774.0
UBA52 -2875.0
PSMB7 -2995.0
PSME4 -3042.0
H4C9 -3283.0
H2AC6 -3373.0
MNAT1 -3468.0
TP73 -3680.0
RUNX1 -3762.0
PSMA6 -3897.0
PSMB2 -4270.0
H4C5 -4637.0
SEM1 -4777.0
ABL1 -4874.0
H4C4 -4917.0
PSMD8 -5041.0
H2AX -5114.0
PSMF1 -5472.0
TAL1 -5570.0
H2BC11 -5816.0
PSMD6 -5971.0
H2BC26 -6669.0
PSMB6 -6874.0
H2BC1 -7617.0
PSME1 -8232.0
PSMB11 -9151.0
SPI1 -9488.0



REACTOME_ASSEMBLY_OF_THE_ORC_COMPLEX_AT_THE_ORIGIN_OF_REPLICATION

REACTOME_ASSEMBLY_OF_THE_ORC_COMPLEX_AT_THE_ORIGIN_OF_REPLICATION
1091
set REACTOME_ASSEMBLY_OF_THE_ORC_COMPLEX_AT_THE_ORIGIN_OF_REPLICATION
setSize 62
pANOVA 6.52e-07
s.dist 0.365
p.adjustANOVA 3.34e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
H4C1 10268.0
H2AC4 10244.0
H3C1 10183.0
H3C6 9987.0
H3C2 9609.0
H3C8 9237.0
H2AJ 9219.0
H4C3 8934.0
H4C8 8774.0
H2AC20 8751.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0
ORC6 8118.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
H4C1 10268.0
H2AC4 10244.0
H3C1 10183.0
H3C6 9987.0
H3C2 9609.0
H3C8 9237.0
H2AJ 9219.0
H4C3 8934.0
H4C8 8774.0
H2AC20 8751.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0
ORC6 8118.0
H2BC9 7978.5
H3C7 7978.5
H2BC21 7828.0
H2AC18 7550.5
H2AC19 7550.5
H3C4 7298.0
ORC4 7082.0
H2BC3 6830.0
H2BC5 6618.0
H2AZ2 6467.0
H2BC10 6026.0
KPNB1 5988.0
H3C11 5197.0
ORC2 4544.0
H2BC15 4475.0
ORC1 4331.0
H2BC8 3188.0
H2AC8 3039.0
H4C16 2382.0
H3C3 2303.0
H4C2 1279.0
H4C11 1080.0
KPNA6 951.0
H2BC13 823.0
H4C6 -340.0
H2BC12 -1288.0
H2AZ1 -1561.0
H2BC4 -2033.0
H3C10 -2100.0
H4C13 -2348.0
H4C12 -2774.0
H4C9 -3283.0
H2AC6 -3373.0
KPNA1 -3430.0
H4C5 -4637.0
H4C4 -4917.0
ORC3 -4974.0
H2AX -5114.0
H2BC11 -5816.0
H2BC26 -6669.0
ORC5 -6898.0
H2BC1 -7617.0



REACTOME_RRNA_PROCESSING

REACTOME_RRNA_PROCESSING
1148
set REACTOME_RRNA_PROCESSING
setSize 192
pANOVA 9.29e-07
s.dist 0.205
p.adjustANOVA 4.62e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS5 10401
UTP20 10207
RPL39L 10015
RPS13 10010
RPLP0 9720
IMP3 9701
SNU13 9681
RRP36 9543
EXOSC5 9460
RPL27 9406
WDR3 9298
RPL6 9269
NIP7 9175
RPL27A 8979
RPS28 8978
RPS8 8920
RPS12 8794
EXOSC8 8764
RPS25 8638
RPL19 8597

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS5 10401.0
UTP20 10207.0
RPL39L 10015.0
RPS13 10010.0
RPLP0 9720.0
IMP3 9701.0
SNU13 9681.0
RRP36 9543.0
EXOSC5 9460.0
RPL27 9406.0
WDR3 9298.0
RPL6 9269.0
NIP7 9175.0
RPL27A 8979.0
RPS28 8978.0
RPS8 8920.0
RPS12 8794.0
EXOSC8 8764.0
RPS25 8638.0
RPL19 8597.0
RPL9 8592.0
NOP2 8577.0
RPL12 8542.0
MRM1 8522.0
RPS6 8501.0
UTP4 8287.0
RPL41 8240.0
RPL18 8234.0
EXOSC9 8176.0
RPL10A 8175.0
NOL12 8142.0
RPS2 8109.0
FAU 8086.0
RPL5 8055.0
RPL36AL 8033.5
RIOK2 8010.0
RPS3A 7941.0
RPL23 7907.0
RPS18 7868.0
FTSJ3 7856.0
MPHOSPH10 7825.0
RPL13 7712.0
GAR1 7709.0
RPS27A 7698.0
RPL13A 7489.5
RPLP2 7348.0
RRP9 7252.0
RPL3 7194.0
RPL4 7148.0
RPS26 6957.0
RPL38 6914.0
RPS21 6901.0
RPL35A 6893.0
RPL21 6804.0
EMG1 6787.0
WDR75 6615.0
RPL28 6441.0
RPL34 6124.0
RPL7 6080.0
RPL17 6034.0
TRMT10C 5994.0
RPS29 5882.0
WDR36 5744.0
RPS15 5697.0
RPL18A 5467.0
TRMT112 5435.0
DDX21 5401.0
RPL32 5357.0
WDR46 5281.0
RPS15A 5210.0
RIOK3 5187.0
RPS10 5051.0
RPS19 5043.0
NOP56 5023.0
RPL35 4765.0
NAT10 4763.0
RPS20 4727.0
IMP4 4723.0
RBM28 4652.0
BYSL 4372.0
UTP15 4351.0
FBL 4272.0
NOB1 4264.0
RIOK1 4250.0
RPP25 4147.0
TSR3 4091.0
NOP58 4068.0
ISG20L2 4028.0
LTV1 3697.0
RPSA 3658.0
RPL26L1 3215.0
RPL8 3119.0
MPHOSPH6 3084.0
PNO1 3075.0
DIMT1 2980.0
RPS24 2748.0
RPP30 2706.0
RPL30 2631.0
RPL37 2527.0
ERI1 2477.0
RPS16 2475.0
RPL11 2329.0
RPS27L 2308.0
RPS23 2004.0
RPP40 1990.0
DCAF13 1958.0
DDX52 1952.0
NHP2 1913.0
KRR1 1863.0
RPL36 1365.0
RPS11 1269.0
RPP21 1142.0
RPS27 1132.0
BUD23 881.0
RPLP1 792.0
UTP14C 750.0
MRM2 624.0
PDCD11 539.0
RPL22 440.0
RPS14 322.0
UTP25 138.0
PRORP 78.0
RPL24 57.0
C1D 4.0
HEATR1 -55.0
RPL14 -57.0
NOL11 -276.0
MTERF4 -324.0
NOP14 -498.0
GNL3 -573.0
UTP18 -623.0
PES1 -692.0
EXOSC1 -737.0
WDR12 -837.0
RPS3 -850.0
TEX10 -1032.0
EXOSC2 -1111.0
PELP1 -1125.0
RPL23A -1287.0
DIS3 -1418.0
NSUN4 -1451.0
EBNA1BP2 -1500.0
UTP6 -1552.0
RPL15 -1589.0
UTP11 -1777.0
RPS9 -1972.0
NCL -2159.0
EXOSC6 -2529.0
EXOSC7 -2703.0
EXOSC3 -2706.0
UBA52 -2875.0
DDX47 -2975.0
NOP10 -3018.0
EXOSC4 -3047.0
MRM3 -3177.0
THUMPD1 -3342.0
RPS7 -3608.0
SENP3 -4078.0
TSR1 -4184.0
RPP38 -4188.0
RPL3L -4519.0
RPL29 -4767.0
FCF1 -4784.0
NOL6 -4793.0
RRP1 -5125.0
XRN2 -5623.0
BMS1 -5656.0
RPL37A -5673.0
MTREX -5758.0
RPL7A -5783.0
NOL9 -5822.0
RPL22L1 -6323.0
EXOSC10 -6330.0
TBL3 -6393.0
UTP3 -6469.0
PWP2 -6487.0
RPL26 -6909.0
BOP1 -7016.0
DHX37 -7089.0
WDR18 -7446.0
RPP14 -7729.0
WDR43 -8007.0
CSNK1D -8034.0
DDX49 -8373.0
TFB1M -8412.0
ELAC2 -8627.0
RPL31 -8668.0
NOC4L -8734.0
RCL1 -9030.0
CSNK1E -9776.0
RPL10L -10702.0
RRP7A -10955.0



REACTOME_DNA_METHYLATION

REACTOME_DNA_METHYLATION
858
set REACTOME_DNA_METHYLATION
setSize 58
pANOVA 9.88e-07
s.dist 0.371
p.adjustANOVA 4.77e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
H4C1 10268.0
H2AC4 10244.0
H3C1 10183.0
H3C6 9987.0
H3C2 9609.0
H3C8 9237.0
H2AJ 9219.0
H4C3 8934.0
H4C8 8774.0
H2AC20 8751.0
UHRF1 8451.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
H4C1 10268.0
H2AC4 10244.0
H3C1 10183.0
H3C6 9987.0
H3C2 9609.0
H3C8 9237.0
H2AJ 9219.0
H4C3 8934.0
H4C8 8774.0
H2AC20 8751.0
UHRF1 8451.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0
H2BC9 7978.5
H3C7 7978.5
H2BC21 7828.0
H2AC18 7550.5
H2AC19 7550.5
H3C4 7298.0
H2BC3 6830.0
H2BC5 6618.0
H2AZ2 6467.0
H2BC10 6026.0
DNMT3L 5870.0
H3C11 5197.0
H2BC15 4475.0
H2BC8 3188.0
H2AC8 3039.0
H4C16 2382.0
H3C3 2303.0
H4C2 1279.0
H4C11 1080.0
H2BC13 823.0
DNMT3A 566.0
H4C6 -340.0
H2BC12 -1288.0
H2AZ1 -1561.0
H2BC4 -2033.0
H3C10 -2100.0
H4C13 -2348.0
H4C12 -2774.0
H4C9 -3283.0
H2AC6 -3373.0
H4C5 -4637.0
DNMT1 -4856.0
H4C4 -4917.0
H2AX -5114.0
DNMT3B -5772.0
H2BC11 -5816.0
H2BC26 -6669.0
H2BC1 -7617.0



REACTOME_RHO_GTPASES_ACTIVATE_PKNS

REACTOME_RHO_GTPASES_ACTIVATE_PKNS
915
set REACTOME_RHO_GTPASES_ACTIVATE_PKNS
setSize 86
pANOVA 1.02e-06
s.dist 0.305
p.adjustANOVA 4.8e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C12 10715
H2BC14 10635
H2AC14 10619
H2BC6 10447
H2BC17 10375
H4C1 10268
H2AC4 10244
KLK2 10225
H3C1 10183
KLK3 10088
H3C6 9987
MYL6 9901
YWHAH 9707
H3C2 9609
H3C8 9237
H2AJ 9219
H4C3 8934
H4C8 8774
H2AC20 8751
H3-3A 8367

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
H4C1 10268.0
H2AC4 10244.0
KLK2 10225.0
H3C1 10183.0
KLK3 10088.0
H3C6 9987.0
MYL6 9901.0
YWHAH 9707.0
H3C2 9609.0
H3C8 9237.0
H2AJ 9219.0
H4C3 8934.0
H4C8 8774.0
H2AC20 8751.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0
RHOB 8154.0
H2BC9 7978.5
H3C7 7978.5
H2BC21 7828.0
H2AC18 7550.5
H2AC19 7550.5
CDC25C 7483.0
H3C4 7298.0
H2BC3 6830.0
YWHAB 6683.0
PKN1 6663.0
H2BC5 6618.0
H2AZ2 6467.0
H2BC10 6026.0
YWHAZ 5941.0
MYH9 5614.0
H3C11 5197.0
H2BC15 4475.0
PPP1R14A 4338.0
YWHAG 3771.0
H2BC8 3188.0
H2AC8 3039.0
KDM1A 2641.0
H4C16 2382.0
H3C3 2303.0
MYH14 1861.0
NCOA2 1402.0
H4C2 1279.0
PDPK1 1252.0
YWHAE 1143.0
H4C11 1080.0
H2BC13 823.0
KDM4C 292.0
PPP1R12A 114.0
PPP1CB -118.0
H4C6 -340.0
PAK1 -345.0
MYL12B -689.0
YWHAQ -694.0
RHOC -843.0
MYH10 -928.0
H2BC12 -1288.0
H2AZ1 -1561.0
H2BC4 -2033.0
H3C10 -2100.0
H4C13 -2348.0
RAC1 -2540.0
H4C12 -2774.0
H4C9 -3283.0
H2AC6 -3373.0
SFN -3911.0
PPP1R12B -3915.0
PKN2 -4465.0
PKN3 -4528.0
H4C5 -4637.0
H4C4 -4917.0
H2AX -5114.0
RHOA -5156.0
H2BC11 -5816.0
H2BC26 -6669.0
H2BC1 -7617.0
MYH11 -7644.0
MYL9 -10556.0



REACTOME_SARS_COV_1_HOST_INTERACTIONS

REACTOME_SARS_COV_1_HOST_INTERACTIONS
1550
set REACTOME_SARS_COV_1_HOST_INTERACTIONS
setSize 92
pANOVA 1.1e-06
s.dist 0.294
p.adjustANOVA 5.01e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS5 10401
RPS13 10010
PYCARD 9962
YWHAH 9707
TOMM70 9433
SMAD4 9393
RIPK3 9358
NFKBIA 9057
RPS28 8978
RPS8 8920
SERPINE1 8895
RPS12 8794
HNRNPA1 8761
SP1 8660
IRAK2 8653
RPS25 8638
RPS6 8501
CAV1 8413
PKLR 8264
RPS2 8109

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS5 10401
RPS13 10010
PYCARD 9962
YWHAH 9707
TOMM70 9433
SMAD4 9393
RIPK3 9358
NFKBIA 9057
RPS28 8978
RPS8 8920
SERPINE1 8895
RPS12 8794
HNRNPA1 8761
SP1 8660
IRAK2 8653
RPS25 8638
RPS6 8501
CAV1 8413
PKLR 8264
RPS2 8109
FAU 8086
RPS3A 7941
PSMC6 7899
RPS18 7868
RPS27A 7698
MAVS 7593
IRF3 7433
UBB 7319
RCAN3 7184
RPS26 6957
PPIA 6915
RPS21 6901
YWHAB 6683
IFIH1 6187
KPNB1 5988
YWHAZ 5941
RPS29 5882
NFKB1 5873
SIKE1 5726
RPS15 5697
RPS15A 5210
RPS10 5051
RPS19 5043
RPS20 4727
IKBKE 4446
ITCH 4318
EEF1A1 3873
YWHAG 3771
PCBP2 3688
RPSA 3658
NMI 3485
NPM1 3477
RELA 2935
KPNA2 2875
RPS24 2748
RIGI 2552
RPS16 2475
RPS27L 2308
RPS23 2004
RPS11 1269
PDPK1 1252
PPIH 1205
YWHAE 1143
RPS27 1132
RPS14 322
TRIM25 3
PPIB -303
TRAF3 -477
UBC -640
YWHAQ -694
RPS3 -850
EP300 -1043
TKFC -1785
RPS9 -1972
UBA52 -2875
PALS1 -3365
BCL2L1 -3377
TBK1 -3532
RPS7 -3608
RUNX1 -3762
SFN -3911
NLRP3 -4141
FKBP1A -4508
PPIG -5700
RIPK1 -5927
SMAD3 -7379
SFTPD -7542
TRAF6 -7812
UBE2I -8350
CASP1 -8384
STING1 -9367
BST2 -9892



REACTOME_SENSORY_PERCEPTION

REACTOME_SENSORY_PERCEPTION
1581
set REACTOME_SENSORY_PERCEPTION
setSize 555
pANOVA 1.17e-06
s.dist -0.121
p.adjustANOVA 5.18e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
OR4C16 -11048
OR2Y1 -11041
OR51D1 -11036
OR10P1 -11006
OR52L1 -10996
OR51F2 -10978
OR10S1 -10958
TAS2R4 -10948
OR8B4 -10940
OR5J2 -10868
OR7G2 -10851
OR6K6 -10813
OR6K3 -10802
OR5L2 -10791
OR52B6 -10724
AKR1B10 -10722
OR5K1 -10713
APOA2 -10684
TAS2R13 -10628
OR1N2 -10625

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
OR4C16 -11048.0
OR2Y1 -11041.0
OR51D1 -11036.0
OR10P1 -11006.0
OR52L1 -10996.0
OR51F2 -10978.0
OR10S1 -10958.0
TAS2R4 -10948.0
OR8B4 -10940.0
OR5J2 -10868.0
OR7G2 -10851.0
OR6K6 -10813.0
OR6K3 -10802.0
OR5L2 -10791.0
OR52B6 -10724.0
AKR1B10 -10722.0
OR5K1 -10713.0
APOA2 -10684.0
TAS2R13 -10628.0
OR1N2 -10625.0
CNGA4 -10600.0
OR4K14 -10586.0
OR4X2 -10521.0
OR52H1 -10520.0
OR4K15 -10477.0
GRXCR2 -10404.0
OR6X1 -10385.0
OR1A1 -10359.0
OR52I2 -10357.0
OR1B1 -10321.0
OR1J1 -10316.0
APOC3 -10305.0
OR10A2 -10283.0
RHO -10274.0
OR2D3 -10254.0
OR7D2 -10231.0
OR2L5 -10189.0
OR10A3 -10163.0
OR4A5 -10134.0
OR2G2 -10113.0
OR51E1 -10097.0
OR1I1 -10057.0
OR1K1 -10016.0
OR2K2 -10015.0
OR9Q2 -10012.0
GRK7 -10002.0
OR10G9 -9991.0
OR8H3 -9983.0
OR2T12 -9941.0
OR10H1 -9925.0
OR4E2 -9886.0
OR5F1 -9878.0
OR1S2 -9874.0
OR5L1 -9859.0
OR52J3 -9855.0
OR1M1 -9831.0
CALHM3 -9794.0
OR1S1 -9767.0
OR10K1 -9750.0
RTP2 -9737.0
OR10H3 -9715.0
OR2AE1 -9712.0
TAS2R3 -9685.0
LRAT -9647.0
OR1J2 -9641.0
OR52K2 -9588.0
OR7G3 -9570.0
ITPR3 -9567.0
OR2J2 -9546.0
TAS2R46 -9531.0
OR1N1 -9513.0
OR2T8 -9495.0
OR2AK2 -9444.0
OR56A5 -9430.0
SLC24A1 -9425.0
OR4D10 -9424.0
TAS1R3 -9411.0
GNAT3 -9408.0
OR8S1 -9406.0
OR8H1 -9405.0
RBP3 -9402.0
OR2M7 -9400.0
RTP1 -9387.0
OR3A2 -9386.0
CABP2 -9332.0
OR10C1 -9263.0
CALHM1 -9181.0
OR52A5 -9180.0
APOA4 -9158.0
CHRNA9 -9130.0
OR10Z1 -9113.0
DHRS9 -9077.0
TAS2R43 -9064.0
TAS2R14 -9051.0
TAS2R7 -9044.0
OR52E2 -9036.0
OR1A2 -9024.0
OR7A10 -8976.0
OTOP1 -8967.0
OR5B21 -8954.0
OR8D1 -8948.0
PDE6B -8935.0
OR4D5 -8890.0
OR13D1 -8871.0
OR8B2 -8855.0
SCNN1D -8846.0
OR2V1 -8788.0
SCNN1A -8787.0
OR11H4 -8765.0
CNGB1 -8673.0
OR4N2 -8653.0
OR52M1 -8618.0
OR4F15 -8593.0
OR10X1 -8581.0
CHRNA10 -8558.0
OR11L1 -8557.0
OR8J1 -8467.0
OR51G1 -8370.0
DNAJC5 -8366.0
OR1L6 -8347.0
OR1G1 -8317.0
OR52W1 -8300.0
OR14A16 -8286.0
CIB2 -8258.0
GNB1 -8243.0
OR1L8 -8229.0
OR5M1 -8223.0
OR11G2 -8152.0
OR8B8 -8052.0
OR6S1 -8041.0
OR13J1 -8019.0
OR8D4 -7817.0
OR6T1 -7802.0
ESPNL -7751.0
OR2T1 -7732.0
OR10V1 -7723.0
OR1C1 -7680.0
OR51I2 -7663.0
GUCA1B -7643.0
OR2F2 -7640.0
OR6C75 -7618.0
OR6K2 -7577.0
OR8K1 -7527.0
OR11A1 -7500.0
OR5K4 -7456.0
AKR1C1 -7449.0
OR6B2 -7437.0
OR10J5 -7411.0
OR2AG1 -7343.0
OR5H6 -7337.0
OR4D9 -7288.0
RBP2 -7261.0
OR2G6 -7181.0
GUCA1C -7176.0
OR10AD1 -7165.0
OR5D13 -7144.0
OR5K2 -7110.0
OR3A3 -7108.0
OR5B12 -7096.0
OR13C3 -7093.0
CAMKMT -6983.0
MYO3B -6982.0
OR2A2 -6947.0
OR4D2 -6937.0
OR52R1 -6901.0
STRC -6896.0
BSN -6830.0
OPN1SW -6824.0
CTBP2 -6812.0
OR14I1 -6810.0
OR2B2 -6763.0
OR52E4 -6762.0
OR2T3 -6664.0
CACNB2 -6636.0
OR2T11 -6635.0
TWF2 -6629.0
OR13G1 -6620.0
OR10A7 -6617.0
OR5D18 -6591.0
CACNA2D2 -6581.0
OR2B11 -6573.0
OR7A17 -6532.0
OR6A2 -6499.0
OR7C2 -6498.0
OR6C6 -6462.0
GNB5 -6344.0
OR8D2 -6156.0
RBP4 -6085.0
OR2L8 -6050.0
SPTAN1 -6040.0
CAPZB -5987.0
LDLR -5969.0
SCNN1G -5957.0
ATP2B1 -5845.0
PDE6A -5807.0
PLCB2 -5798.0
OR1F1 -5723.0
LRP1 -5698.0
TRIOBP -5680.0
LRP12 -5651.0
RDH5 -5582.0
OR6F1 -5579.0
ATP2B2 -5553.0
MYO7A -5550.0
GNG13 -5549.0
EPB41L3 -5491.0
RDH12 -5464.0
TRPM5 -5426.0
PDE6G -5406.0
MYO15A -5255.0
TTR -5242.0
TAS2R38 -5180.0
FNTB -5167.0
OR5AK2 -5121.0
RDH16 -5059.0
METAP1 -5055.0
GRK1 -5045.0
OR4D1 -4998.0
OR8K3 -4963.0
WHRN -4961.0
CNGA1 -4909.0
OR51M1 -4870.0
CLIC5 -4799.0
SCNN1B -4728.0
OR52A1 -4665.0
OR10G8 -4580.0
OR51L1 -4556.0
TAS2R40 -4535.0
RBP1 -4485.0
OR52B2 -4375.0
TAS2R8 -4368.0
USH1C -4365.0
OR1E1 -4353.0
BCO2 -4337.0
EPS8 -4227.0
KCNMA1 -4193.0
OR4M1 -4144.0
OR2S2 -4140.0
OR5AU1 -4096.0
PLB1 -4056.0
GPIHBP1 -4042.0
OR6V1 -4035.0
OR51E2 -4034.0
SNAP25 -3838.0
CALM1 -3834.0
OR51Q1 -3700.0
APOM -3628.0
BCO1 -3624.0
OR4X1 -3604.0
OR5M9 -3579.0
APOA1 -3516.0
OR2L13 -3507.0
OR2T27 -3469.0
CAPZA2 -3425.0
PRKCA -3379.0
LRP8 -3286.0
OR51G2 -3263.0
TAS1R2 -3151.0
ANO2 -3083.0
OR10J3 -3025.0
OR51B6 -3021.0
OR4L1 -2898.0
OR10K2 -2881.0
OR10J1 -2698.0
OR1D2 -2687.0
HSPG2 -2636.0
RPE65 -2593.0
PCDH15 -2526.0
OR2A14 -2438.0
OR1L4 -2421.0
OR2M3 -2395.0
KCNMB1 -2383.0
OTOF -2369.0
RDH8 -2344.0
OR51I1 -2333.0
OR10H2 -2322.0
OR2F1 -2231.0
TAS2R20 -2211.0
OR5M11 -2209.0
SCN1B -2170.0
OR10H4 -2151.0
CACNA1D -2145.0
KCNQ4 -2144.0
SCN3A -2117.0
AGRN -2079.0
GPC5 -1984.0
OTOG -1982.0
OR5D16 -1942.0
OR14J1 -1886.0
REEP1 -1881.0
CDH23 -1864.0
OR7A5 -1821.0
NAPEPLD -1806.0
LHFPL5 -1707.0
OR8B12 -1676.0
OR2C1 -1631.0
OR2W1 -1584.0
OR6C1 -1571.0
OR4K2 -1430.0
OR2V2 -1401.0
PLS1 -1332.0
PCLO -1294.0
OR5T2 -1257.0
GRK4 -1213.0
PJVK -1188.0
ADCY3 -1144.0
GNB3 -1112.0
ABCA4 -1007.0
GRM1 -951.0
OR6Q1 -856.0
OR6C65 -767.0
FNTA -654.0
OR6Y1 -636.0
TAS2R50 -618.0
OR10A6 -616.0
SCN2B -607.0
OR6P1 -601.0
EPB41L1 -593.0
OR5A1 -531.0
OR51B2 -466.0
OR3A1 -448.0
NMT1 -407.0
RAB3A -151.0
APOB -110.0
OR5AN1 -80.0
OR2Z1 -23.0
GUCA1A -20.0
OR5H1 12.0
TRPM4 17.0
OR2L3 97.0
OR6B1 184.0
PNLIP 314.0
GPC1 381.0
OR4C46 405.0
SDC4 552.0
OR2AG2 571.0
OR5AP2 579.0
OR4C12 592.0
GSN 598.0
OR2D2 602.0
OR2W3 665.0
OR13F1 704.0
OR8J3 722.0
HSD17B6 807.0
KCNJ2 838.0
OR5V1 868.0
OR9G4 939.0
GRXCR1 941.0
OR2C3 957.0
OR2H1 1037.0
LRP10 1085.0
OR5A2 1101.0
OR9A4 1103.0
CYP4V2 1190.0
GUCY2D 1193.0
EZR 1194.0
OR51A2 1360.0
GNAT1 1382.0
SAG 1433.0
OR13C8 1598.0
TAS2R16 1725.0
SCN9A 1770.0
GPC6 1790.0
OR8I2 1895.0
OR5B3 1899.0
OR52D1 1953.0
TAS2R10 2031.0
TAS2R5 2054.0
OR4C15 2116.0
OR10A5 2246.0
OR1L1 2318.0
RETSAT 2319.0
OR11H6 2363.0
OR9I1 2384.0
CAPZA1 2409.0
SLC17A8 2420.0
TMC2 2453.0
OR8U1 2510.0
TAS1R1 2547.0
GRM4 2592.0
DHRS3 2735.0
OR12D3 2784.0
USH1G 2812.0
OR2G3 2855.0
TAS2R30 3054.0
FSCN2 3081.0
OR7G1 3129.0
OR13A1 3154.0
OR4A15 3197.0
CABP1 3204.0
OR13C9 3217.0
RDH10 3252.0
OR9G1 3319.5
OR9G9 3319.5
SDC1 3420.0
SLC26A5 3506.0
TAS2R31 3518.0
RDX 3609.0
OR56A4 3628.0
OR51V1 3683.0
OR4K17 3706.0
XIRP2 3768.0
TMC1 3791.0
PRKCQ 3885.0
RIPOR2 3907.0
OR2A5 3942.0
SCN4B 4106.0
OR52N2 4119.0
KCNN2 4148.0
MYO3A 4222.0
OR52E6 4229.0
OR4N5 4422.0
OR10G4 4556.0
OR5AS1 4559.0
GNGT1 4563.0
OR5P2 4575.0
LRP2 4649.0
OR5M8 4703.0
RDH11 4747.0
RGS9 4754.0
OR5B2 4894.0
OR56A1 4981.0
OR8U8 5025.0
SPTBN1 5039.0
EPS8L2 5086.0
EBF1 5111.0
LPL 5238.0
TWF1 5261.0
OR8K5 5379.0
OR51S1 5436.0
OR1J4 5484.0
METAP2 5539.0
NMT2 5580.0
MYH9 5614.0
OR1L3 5660.0
SCN2A 5733.0
OR4K13 5737.0
TAS2R41 5777.0
GPC2 5787.0
OR2A12 5839.0
OR5P3 5875.0
OR2T6 5948.0
OR4F6 6086.0
OR5K3 6090.0
OR5W2 6320.0
OR52K1 6321.0
OR51B5 6426.0
OR56B1 6430.0
HSD17B1 6458.0
OR4C45 6561.0
RCVRN 6584.0
GNAL 6628.0
SDC2 6638.0
OR4B1 6645.0
OR9Q1 6651.0
TPRN 6701.0
OR51A7 6720.0
MYO1C 6734.0
OR2T33 6848.0
OR5B17 6889.0
VAMP2 6897.0
OR4D6 6934.0
OR8G1 6939.0
OR13C2 6979.0
OR4D11 6982.0
OR2M5 6987.0
OR52E8 7030.0
OR2T4 7037.0
OR2M2 7063.0
OR2B3 7172.0
AKR1C3 7183.0
OR10Q1 7203.0
OR7C1 7358.0
OR9A2 7460.0
OR6C68 7472.0
OR5H15 7522.0
OR8G5 7526.0
OR10W1 7544.0
OR12D2 7562.0
OR51T1 7646.0
OR7D4 7756.0
OR6N2 7780.0
OR8U3 7786.0
OR10G2 7946.0
OR5T1 7992.0
OR6C3 8044.0
TAS2R39 8054.0
OR4K5 8063.0
OR2AT4 8071.0
LHX2 8124.0
SDR9C7 8173.0
OR4A47 8204.0
OR56A3 8256.0
OR2L2 8279.0
APOE 8293.0
OR6N1 8325.0
ESPN 8385.0
OR10G7 8397.0
OR10A4 8499.0
AKR1C4 8554.0
OR14C36 8600.0
OR5T3 8622.0
TMIE 8697.0
OR6M1 8713.0
OR6C2 8740.0
OR1E2 8807.0
OR10H5 8852.0
TAS2R1 9035.0
OTOGL 9054.0
RGS9BP 9114.0
OR5C1 9121.0
OR52N1 9142.0
OR7E24 9148.0
STX1A 9223.0
OR10G3 9247.0
OR6B3 9272.0
OR4S1 9313.0
OR4K1 9332.0
OR4C6 9339.0
OR5I1 9385.0
OR6C76 9421.0
ACTG1 9424.0
OR51B4 9557.0
RLBP1 9616.0
OR2AP1 9656.0
OR5D14 9741.0
OR2M4 9750.0
APOC2 9765.0
OR5M10 9790.0
OR56B4 9798.0
CLPS 9909.0
STRA6 9958.0
OR51F1 9959.0
SDC3 10002.0
LDB1 10030.0
OR5AC2 10058.0
ACTB 10161.0
OR52I1 10282.0
OR5AR1 10291.0
OR9K2 10312.0
OR1Q1 10351.0
OR10AG1 10370.0
OR5H2 10400.0
OR4C3 10424.0
OR13C4 10459.0
OR4A16 10500.0
OR6C74 10513.0
OR6C70 10535.0
OR8A1 10568.0
OR5M3 10586.0
OR2H2 10597.0
OR2B6 10606.0
OR10T2 10736.0
OR6C4 10764.0
LRRC52 10779.0



REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY

REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY
1591
set REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY
setSize 33
pANOVA 1.3e-06
s.dist 0.487
p.adjustANOVA 5.6e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS5 10401
RPS13 10010
RPS28 8978
RPS8 8920
RPS12 8794
HNRNPA1 8761
RPS25 8638
RPS6 8501
RPS2 8109
FAU 8086
RPS3A 7941
RPS18 7868
RPS27A 7698
RPS26 6957
RPS21 6901
RPS29 5882
RPS15 5697
RPS15A 5210
RPS10 5051
RPS19 5043

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS5 10401
RPS13 10010
RPS28 8978
RPS8 8920
RPS12 8794
HNRNPA1 8761
RPS25 8638
RPS6 8501
RPS2 8109
FAU 8086
RPS3A 7941
RPS18 7868
RPS27A 7698
RPS26 6957
RPS21 6901
RPS29 5882
RPS15 5697
RPS15A 5210
RPS10 5051
RPS19 5043
RPS20 4727
EEF1A1 3873
RPSA 3658
RPS24 2748
RPS16 2475
RPS27L 2308
RPS23 2004
RPS11 1269
RPS27 1132
RPS14 322
RPS3 -850
RPS9 -1972
RPS7 -3608



REACTOME_RHO_GTPASE_EFFECTORS

REACTOME_RHO_GTPASE_EFFECTORS
342
set REACTOME_RHO_GTPASE_EFFECTORS
setSize 305
pANOVA 1.54e-06
s.dist 0.16
p.adjustANOVA 6.48e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C12 10715
TUBB8 10699
H2BC14 10635
H2AC14 10619
TUBB4B 10590
H2BC6 10447
H2BC17 10375
DYNLL2 10298
H4C1 10268
H2AC4 10244
KLK2 10225
H3C1 10183
ACTB 10161
KLK3 10088
PFN1 9999
H3C6 9987
TAX1BP3 9946
MAPRE1 9923
WASF1 9903
MYL6 9901

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C12 10715.0
TUBB8 10699.0
H2BC14 10635.0
H2AC14 10619.0
TUBB4B 10590.0
H2BC6 10447.0
H2BC17 10375.0
DYNLL2 10298.0
H4C1 10268.0
H2AC4 10244.0
KLK2 10225.0
H3C1 10183.0
ACTB 10161.0
KLK3 10088.0
PFN1 9999.0
H3C6 9987.0
TAX1BP3 9946.0
MAPRE1 9923.0
WASF1 9903.0
MYL6 9901.0
KIF2A 9896.0
KNL1 9842.0
YWHAH 9707.0
CFL1 9660.0
H3C2 9609.0
ACTR3 9606.0
KLC3 9583.0
S100A8 9559.0
ACTG1 9424.0
MAD2L1 9381.0
H3C8 9237.0
H2AJ 9219.0
S100A9 9081.0
NDEL1 8967.0
H4C3 8934.0
H4C8 8774.0
H2AC20 8751.0
ZWINT 8650.0
TUBA4B 8566.0
ARPC3 8491.0
CENPM 8454.0
TUBB2B 8395.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0
TUBA4A 8265.0
RHOB 8154.0
CFTR 8134.0
FMNL1 8111.0
NSL1 8084.0
H2BC9 7978.5
H3C7 7978.5
SPC24 7943.0
H2BC21 7828.0
KIF5A 7697.0
XPO1 7679.0
CENPE 7598.0
H2AC18 7550.5
H2AC19 7550.5
SCAI 7500.0
CDC25C 7483.0
PLK1 7394.0
H3C4 7298.0
CENPA 7291.0
TUBA1B 7189.0
PAFAH1B1 7087.0
TUBB4A 7002.0
PPP2R1A 6985.0
NCKAP1 6948.0
ABI1 6929.0
H2BC3 6830.0
YWHAB 6683.0
PKN1 6663.0
H2BC5 6618.0
DLG4 6573.0
H2AZ2 6467.0
NDC80 6455.0
AURKB 6374.0
NUP160 6067.0
H2BC10 6026.0
YWHAZ 5941.0
SPC25 5934.0
RHPN2 5871.0
MIS12 5708.0
SKA1 5694.0
ARPC4 5654.0
NOXA1 5625.0
MYH9 5614.0
PMF1 5583.0
ARPC5 5557.0
RANBP2 5556.0
CENPK 5486.0
NUP107 5390.0
DIAPH1 5334.0
SEH1L 5251.0
H3C11 5197.0
PPP2R5A 5135.0
CDC20 5122.0
PTK2 5116.0
WASL 5035.0
KIF18A 4930.0
PFN2 4863.0
CYBA 4856.0
ARPC2 4670.0
MAPK14 4661.0
BUB1B 4566.0
BRK1 4501.0
H2BC15 4475.0
PPP1R14A 4338.0
SKA2 4335.0
WIPF1 4310.0
PPP2R5B 4283.0
NUP37 4196.0
CTNNB1 4071.0
DYNC1LI2 4052.0
DAAM1 4049.0
BAIAP2 3979.0
SGO1 3934.0
RTKN 3883.0
CENPL 3837.0
TUBB6 3809.0
YWHAG 3771.0
GOPC 3626.0
FMNL3 3570.0
NUP85 3458.0
RHPN1 3400.0
TAOK1 3289.0
DSN1 3269.0
WIPF3 3190.0
H2BC8 3188.0
NUF2 3136.0
CENPT 3121.0
CDCA8 3106.0
CENPC 3064.0
H2AC8 3039.0
PPP2R5E 3022.0
NUP133 2881.0
PIK3R4 2871.0
PPP2R5D 2818.0
ARPC1A 2775.0
B9D2 2744.0
KIF5B 2649.0
KDM1A 2641.0
CENPS 2624.0
TUBA1A 2579.0
NOX3 2516.0
H4C16 2382.0
SPDL1 2374.0
ROCK1 2309.0
H3C3 2303.0
DVL2 2267.0
KNTC1 2148.0
KTN1 1951.0
MYH14 1861.0
DYNLL1 1562.0
ABI2 1447.0
NCOA2 1402.0
SRF 1400.0
MEN1 1353.0
H4C2 1279.0
PDPK1 1252.0
PPP2CB 1242.0
YWHAE 1143.0
RPS27 1132.0
H4C11 1080.0
CENPH 938.0
CTNNA1 901.0
KIF14 894.0
H2BC13 823.0
RAC2 697.0
ZW10 644.0
CENPO 442.0
CLASP2 412.0
KLC4 352.0
WIPF2 294.0
NOXO1 293.0
KDM4C 292.0
ZWILCH 197.0
MRTFA 165.0
PPP1R12A 114.0
NUDC 91.0
PPP2CA -89.0
PPP1CB -118.0
DYNC1LI1 -141.0
TUBB3 -261.0
CENPN -305.0
H4C6 -340.0
PAK1 -345.0
DIAPH3 -495.0
CDKN1B -509.0
NDE1 -565.0
TUBB1 -568.0
BUB1 -631.0
MYL12B -689.0
YWHAQ -694.0
WASF3 -742.0
WASF2 -828.0
RHOC -843.0
MYH10 -928.0
AHCTF1 -1001.0
EVL -1009.0
KLC2 -1167.0
PRC1 -1205.0
H2BC12 -1288.0
PPP2R5C -1316.0
NUP98 -1370.0
BUB3 -1503.0
H2AZ1 -1561.0
DVL3 -1721.0
CENPQ -1771.0
PPP1CC -1773.0
FMNL2 -1859.0
PRKCB -1916.0
CDC42 -1927.0
H2BC4 -2033.0
H3C10 -2100.0
NF2 -2154.0
H4C13 -2348.0
PRKCD -2402.0
RCC2 -2441.0
CKAP5 -2537.0
RAC1 -2540.0
CENPP -2623.0
CYFIP2 -2641.0
KIF2C -2754.0
DYNC1I2 -2769.0
H4C12 -2774.0
RHOD -3100.0
CDH1 -3204.0
H4C9 -3283.0
NCK1 -3321.0
H2AC6 -3373.0
PRKCA -3379.0
MAPK11 -3435.0
SRC -3509.0
INCENP -3590.0
GRB2 -3685.0
NCKAP1L -3726.0
ITGB3BP -3785.0
CALM1 -3834.0
SFN -3911.0
PPP1R12B -3915.0
CLASP1 -3976.0
LIMK1 -4094.0
CTTN -4119.0
NCF2 -4279.0
CIT -4459.0
PKN2 -4465.0
PAK2 -4482.0
CENPF -4488.0
TUBA8 -4516.0
KLC1 -4527.0
PKN3 -4528.0
TUBA1C -4583.0
H4C5 -4637.0
LIN7B -4755.0
SGO2 -4765.0
NCKIPSD -4774.0
SEC13 -4820.0
ABL1 -4874.0
H4C4 -4917.0
H2AX -5114.0
RHOA -5156.0
ACTR2 -5323.0
PIN1 -5386.0
ARPC1B -5416.0
TUBB2A -5696.0
MAD1L1 -5791.0
H2BC11 -5816.0
MYLK -5898.0
PIK3C3 -5979.0
NUP43 -6011.0
NCF4 -6016.0
IQGAP1 -6029.0
CENPU -6237.0
DYNC1H1 -6369.0
PRKCZ -6560.0
H2BC26 -6669.0
MAPK1 -6741.0
ITGB1 -6845.0
IQGAP2 -6867.0
RHOG -6872.0
CLIP1 -7030.0
ROCK2 -7167.0
RHOQ -7402.0
MAPK3 -7453.0
H2BC1 -7617.0
MYH11 -7644.0
DVL1 -7756.0
DYNC1I1 -7779.0
IQGAP3 -8458.0
PPP2R1B -8545.0
BIRC5 -8677.0
RANGAP1 -9421.0
TUBA3C -9626.0
CYFIP1 -9697.0
LIMK2 -9931.0
TUBAL3 -9995.0
SRGAP2 -10049.0
MYL9 -10556.0
KIF2B -10643.0
TUBA3D -10657.0
ROPN1 -10718.0
TUBA3E -11051.0



REACTOME_DISEASES_OF_PROGRAMMED_CELL_DEATH

REACTOME_DISEASES_OF_PROGRAMMED_CELL_DEATH
1502
set REACTOME_DISEASES_OF_PROGRAMMED_CELL_DEATH
setSize 96
pANOVA 1.66e-06
s.dist 0.283
p.adjustANOVA 6.8e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C12 10715
H2BC14 10635
H2AC14 10619
FASLG 10485
H2BC6 10447
H2BC17 10375
H4C1 10268
H2AC4 10244
H3C1 10183
H3C6 9987
H3C2 9609
CDC25B 9568
JUN 9518
RIPK3 9358
H3C8 9237
H2AJ 9219
H4C3 8934
H4C8 8774
H2AC20 8751
H3-3A 8367

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
FASLG 10485.0
H2BC6 10447.0
H2BC17 10375.0
H4C1 10268.0
H2AC4 10244.0
H3C1 10183.0
H3C6 9987.0
H3C2 9609.0
CDC25B 9568.0
JUN 9518.0
RIPK3 9358.0
H3C8 9237.0
H2AJ 9219.0
H4C3 8934.0
H4C8 8774.0
H2AC20 8751.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0
TP53 8272.0
PRIM1 8152.0
H2BC9 7978.5
H3C7 7978.5
CDK5 7920.0
CAPNS2 7877.0
H2BC21 7828.0
H2AC18 7550.5
H2AC19 7550.5
CDC25C 7483.0
CAPNS1 7415.0
H3C4 7298.0
PRDX2 7131.0
H2BC3 6830.0
CDK5R1 6681.0
H2BC5 6618.0
H2AZ2 6467.0
TRADD 6270.0
H2BC10 6026.0
POLA2 5403.0
H3C11 5197.0
H2BC15 4475.0
FADD 4056.0
PRDX1 3266.0
H2BC8 3188.0
H2AC8 3039.0
CDKN2A 2953.0
C1QBP 2851.0
H4C16 2382.0
H3C3 2303.0
CAPN1 2260.0
MLKL 1775.0
CASP8 1497.0
H4C2 1279.0
YWHAE 1143.0
H4C11 1080.0
PRIM2 961.0
H2BC13 823.0
DNMT3A 566.0
BCL2L11 -152.0
H4C6 -340.0
RBBP4 -414.0
GSDME -431.0
SUZ12 -1050.0
H2BC12 -1288.0
H2AZ1 -1561.0
SOD2 -2013.0
H2BC4 -2033.0
H3C10 -2100.0
CAST -2104.0
H4C13 -2348.0
H4C12 -2774.0
CAPN2 -2800.0
APP -2885.0
H4C9 -3283.0
H2AC6 -3373.0
EZH2 -3560.0
EED -3682.0
CDC25A -3836.0
H4C5 -4637.0
DNMT1 -4856.0
H4C4 -4917.0
H2AX -5114.0
DNMT3B -5772.0
H2BC11 -5816.0
RIPK1 -5927.0
LMNB1 -5936.0
GOLGA2 -6534.0
H2BC26 -6669.0
LMNA -6719.0
FOXO3 -6829.0
H2BC1 -7617.0
TRAF2 -7698.0



REACTOME_RNA_POLYMERASE_I_PROMOTER_ESCAPE

REACTOME_RNA_POLYMERASE_I_PROMOTER_ESCAPE
1157
set REACTOME_RNA_POLYMERASE_I_PROMOTER_ESCAPE
setSize 83
pANOVA 1.73e-06
s.dist 0.304
p.adjustANOVA 6.92e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
H4C1 10268.0
H2AC4 10244.0
H3C1 10183.0
H3C6 9987.0
H3C2 9609.0
GTF2H3 9509.0
POLR1H 9366.0
POLR2K 9241.0
H3C8 9237.0
H2AJ 9219.0
H4C3 8934.0
H4C8 8774.0
H2AC20 8751.0
H3-3A 8367.0
H2AC7 8363.5

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
H4C1 10268.0
H2AC4 10244.0
H3C1 10183.0
H3C6 9987.0
H3C2 9609.0
GTF2H3 9509.0
POLR1H 9366.0
POLR2K 9241.0
H3C8 9237.0
H2AJ 9219.0
H4C3 8934.0
H4C8 8774.0
H2AC20 8751.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0
H2BC9 7978.5
H3C7 7978.5
H2BC21 7828.0
POLR1E 7682.0
H2AC18 7550.5
H2AC19 7550.5
H3C4 7298.0
TAF1A 7141.0
H2BC3 6830.0
UBTF 6759.0
H2BC5 6618.0
H2AZ2 6467.0
POLR1G 6379.0
H2BC10 6026.0
CBX3 5646.0
TAF1B 5541.0
H3C11 5197.0
POLR2H 4937.0
H2BC15 4475.0
TBP 3926.0
H2BC8 3188.0
POLR1D 3137.0
H2AC8 3039.0
POLR1A 2598.0
CDK7 2530.0
H4C16 2382.0
POLR1B 2328.0
H3C3 2303.0
POLR2E 1875.0
H4C2 1279.0
H4C11 1080.0
CCNH 840.0
H2BC13 823.0
ERCC2 808.0
TAF1D 291.0
GTF2H5 189.0
H4C6 -340.0
H2BC12 -1288.0
TAF1C -1359.0
H2AZ1 -1561.0
GTF2H1 -1760.0
H2BC4 -2033.0
H3C10 -2100.0
H4C13 -2348.0
H4C12 -2774.0
H4C9 -3283.0
H2AC6 -3373.0
MNAT1 -3468.0
POLR2F -3844.0
GTF2H4 -4059.0
POLR2L -4399.0
POLR1C -4599.0
H4C5 -4637.0
H4C4 -4917.0
H2AX -5114.0
H2BC11 -5816.0
H2BC26 -6669.0
H2BC1 -7617.0
RRN3 -8272.0
POLR1F -9054.0
ERCC3 -9580.0



REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION
116
set REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION
setSize 291
pANOVA 1.97e-06
s.dist -0.162
p.adjustANOVA 7.72e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
PECAM1 -10668
CAPN15 -10405
FURIN -10395
CEACAM8 -10390
LUM -10239
CTSL -10161
CTSB -10101
COL15A1 -10087
MMP8 -9903
CD151 -9888
MMP20 -9658
MATN1 -9640
CAPN9 -9637
OPTC -9564
ADAMTS14 -9549
THBS1 -9517
PXDN -9410
DMP1 -9335
ADAMTS16 -9322
KLK7 -9295

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PECAM1 -10668
CAPN15 -10405
FURIN -10395
CEACAM8 -10390
LUM -10239
CTSL -10161
CTSB -10101
COL15A1 -10087
MMP8 -9903
CD151 -9888
MMP20 -9658
MATN1 -9640
CAPN9 -9637
OPTC -9564
ADAMTS14 -9549
THBS1 -9517
PXDN -9410
DMP1 -9335
ADAMTS16 -9322
KLK7 -9295
GDF5 -9260
TMPRSS6 -9123
ADAM8 -9034
CAPN8 -8923
ITGAM -8861
MFAP5 -8843
SCUBE1 -8785
BMP10 -8708
MMP12 -8700
CAPN3 -8669
CAPN10 -8638
FBN3 -8622
LAMC3 -8515
MMP10 -8503
MFAP4 -8459
ELN -8448
MMP16 -8335
LAMB1 -8295
A2M -8220
MMP24 -8073
MMP15 -8072
LAMA1 -8038
FBLN1 -7970
DAG1 -7956
TGFB3 -7948
COL1A2 -7903
COL20A1 -7825
CEACAM1 -7594
DSPP -7508
ADAMTS9 -7496
COL5A1 -7481
COL28A1 -7398
TGFB2 -7295
ITGA7 -7248
NTN4 -7246
COL7A1 -7204
ADAMTS5 -7168
PRSS1 -7166
CTRB1 -6957
LTBP1 -6920
ITGB1 -6845
ADAM19 -6813
DCN -6739
COL6A2 -6609
COL9A2 -6548
LOX -6510
COL8A2 -6426
KLKB1 -6405
MMP11 -6349
COL11A2 -6345
FGA -6343
ITGAX -6274
ADAMTS2 -6261
FGB -6168
PLOD2 -6081
ADAM12 -6071
CTSK -5955
P4HA3 -5944
LAMB2 -5894
COL13A1 -5800
BMP1 -5764
FBN2 -5634
ITGB4 -5631
COL4A2 -5479
FBLN2 -5444
ADAM15 -5414
ITGB5 -5409
VCAN -5340
COL17A1 -5267
MATN4 -5251
COL6A1 -5246
TTR -5242
DDR2 -5226
COMP -5206
TLL1 -5182
ICAM4 -5152
CTSG -5106
TNR -4946
ITGB6 -4835
ITGB3 -4701
ITGAV -4604
ITGB8 -4602
LAMA5 -4597
COL4A1 -4586
MADCAM1 -4578
LTBP2 -4565
SPOCK3 -4558
PCOLCE -4522
CMA1 -4346
CAPN14 -4065
COL4A4 -4040
PTPRS -3964
CEACAM6 -3952
EMILIN2 -3944
COL10A1 -3923
LOXL4 -3909
COL2A1 -3898
ITGA1 -3896
PLOD1 -3835
VTN -3794
TNC -3775
BMP4 -3723
PLOD3 -3653
LOXL2 -3645
CAPN7 -3555
PRKCA -3379
ITGAE -3344
CASP3 -3290
COL18A1 -3240
CDH1 -3204
ADAMTS3 -3176
P3H1 -3162
FN1 -3136
COL5A3 -3122
CAPN12 -3036
COL6A3 -3016
ASPN -2896
NRXN1 -2888
APP -2885
BSG -2874
COLGALT2 -2826
MMP1 -2814
CAPN2 -2800
ADAM9 -2763
EFEMP1 -2751
TIMP2 -2740
NID1 -2730
ITGA10 -2657
HSPG2 -2636
CD47 -2626
NCAM1 -2531
COL27A1 -2525
CAPN5 -2462
ADAM10 -2382
ADAMTS4 -2356
ITGA2 -2276
BMP7 -2268
ADAMTS18 -2251
FMOD -2197
CTSS -2183
CAST -2104
COL21A1 -2101
AGRN -2079
P3H3 -2074
VWF -2069
ADAMTS1 -1945
MMP14 -1875
CTRB2 -1738
ELANE -1638
LAMC1 -1628
SCUBE3 -1619
LTBP4 -1515
COLGALT1 -1382
CTSD -1335
SERPINH1 -1176
LAMA2 -1153
MMP2 -1143
MUSK -1064
PHYKPL -782
LOXL1 -743
ACAN -709
EMILIN3 -681
TNXB -670
COL9A1 -662
SH3PXD2A -587
LAMA4 -384
COL16A1 -367
P4HA1 -332
PPIB -303
COL23A1 -204
MMP19 -128
NCAN -76
HTRA1 -49
F11R -39
ADAMTS8 25
MMP25 44
COL3A1 136
COL22A1 200
ITGA3 230
MFAP3 357
TGFB1 382
ITGA9 465
LTBP3 492
EMILIN1 507
JAM3 525
SDC4 552
MMP3 636
IBSP 676
COL25A1 719
DST 857
MMP13 912
COL8A1 1113
TNN 1206
HAPLN1 1208
JAM2 1249
COL5A2 1305
P3H2 1395
PLEC 1441
COL1A1 1500
MATN3 1617
ITGAL 1731
ITGB7 1883
ITGAD 1978
ITGA2B 2129
CAPN1 2260
LOXL3 2356
MMP7 2424
KDR 2529
CRTAP 2702
FGF2 2805
ADAM17 2945
PCOLCE2 2995
LAMB3 3207
NID2 3275
COL4A3 3309
SDC1 3420
FBN1 3529
PLG 3763
NCSTN 3871
SPP1 4006
EFEMP2 4007
COL26A1 4067
CAPN11 4206
COL12A1 4373
TLL2 4379
VCAM1 4539
CD44 4627
MMP17 4632
COL24A1 4769
ITGA8 4907
PDGFB 5059
FBLN5 5260
COL9A3 5316
SPARC 5372
PSEN1 5385
ITGA4 5389
COL6A5 5434
COL14A1 5843
P4HA2 6163
COL6A6 6263
FGG 6408
ICAM2 6616
SDC2 6638
MMP9 6664
LAMA3 6685
ICAM3 6845
COL11A1 6853
BMP2 6973
COL19A1 7115
CAPNS1 7415
ACTN1 7737
CAPNS2 7877
ITGA11 8083
LAMC2 8156
TRAPPC4 8185
ITGA5 8230
ICAM5 8314
ITGB2 8547
ITGA6 8693
CAPN13 8718
PDGFA 8841
BCAN 8867
SERPINE1 8895
LRP4 9443
MFAP2 9754
P4HB 9800
CTSV 9850
DDR1 9898
ICAM1 9989
SDC3 10002
KLK2 10225



REACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS

REACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS
1476
set REACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS
setSize 83
pANOVA 2.08e-06
s.dist 0.301
p.adjustANOVA 7.96e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
H4C1 10268.0
H2AC4 10244.0
LEF1 10209.0
H3C1 10183.0
H3C6 9987.0
H3C2 9609.0
CDK4 9521.0
H3C8 9237.0
H2AJ 9219.0
H4C3 8934.0
H4C8 8774.0
H2AC20 8751.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
H4C1 10268.0
H2AC4 10244.0
LEF1 10209.0
H3C1 10183.0
H3C6 9987.0
H3C2 9609.0
CDK4 9521.0
H3C8 9237.0
H2AJ 9219.0
H4C3 8934.0
H4C8 8774.0
H2AC20 8751.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0
H2BC9 7978.5
H3C7 7978.5
H2BC21 7828.0
CEBPB 7763.0
MYC 7649.0
GATA2 7561.0
H2AC18 7550.5
H2AC19 7550.5
RARA 7478.0
H3C4 7298.0
E2F1 7180.0
GFI1 6842.0
H2BC3 6830.0
H2BC5 6618.0
H2AZ2 6467.0
CEBPA 6078.0
H2BC10 6026.0
STAT3 5799.0
KMT2A 5747.0
H3C11 5197.0
CREB1 4963.0
H2BC15 4475.0
PML 3902.0
MYB 3605.0
CDK2 3557.0
H2BC8 3188.0
H2AC8 3039.0
H4C16 2382.0
H3C3 2303.0
H4C2 1279.0
H4C11 1080.0
H2BC13 823.0
CBFB -58.0
RXRA -296.0
H4C6 -340.0
TFDP2 -533.0
CDKN1A -800.0
EP300 -1043.0
H2BC12 -1288.0
H2AZ1 -1561.0
H2BC4 -2033.0
H3C10 -2100.0
H4C13 -2348.0
H4C12 -2774.0
CSF3R -3155.0
H4C9 -3283.0
H2AC6 -3373.0
FLI1 -3725.0
RUNX1 -3762.0
IL6R -4160.0
H4C5 -4637.0
H4C4 -4917.0
H2AX -5114.0
TAL1 -5570.0
CEBPE -5702.0
H2BC11 -5816.0
KLF5 -6314.0
TFDP1 -6580.0
H2BC26 -6669.0
H2BC1 -7617.0
DEK -8516.0
SPI1 -9488.0



REACTOME_ERCC6_CSB_AND_EHMT2_G9A_POSITIVELY_REGULATE_RRNA_EXPRESSION

REACTOME_ERCC6_CSB_AND_EHMT2_G9A_POSITIVELY_REGULATE_RRNA_EXPRESSION
738
set REACTOME_ERCC6_CSB_AND_EHMT2_G9A_POSITIVELY_REGULATE_RRNA_EXPRESSION
setSize 68
pANOVA 2.86e-06
s.dist 0.328
p.adjustANOVA 0.000107



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
H4C1 10268.0
H2AC4 10244.0
H3C1 10183.0
H3C6 9987.0
H3C2 9609.0
H3C8 9237.0
H2AJ 9219.0
H4C3 8934.0
H4C8 8774.0
H2AC20 8751.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0
H2BC9 7978.5

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
H4C1 10268.0
H2AC4 10244.0
H3C1 10183.0
H3C6 9987.0
H3C2 9609.0
H3C8 9237.0
H2AJ 9219.0
H4C3 8934.0
H4C8 8774.0
H2AC20 8751.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0
H2BC9 7978.5
H3C7 7978.5
H2BC21 7828.0
TTF1 7629.0
H2AC18 7550.5
H2AC19 7550.5
H3C4 7298.0
HDAC2 6890.0
H2BC3 6830.0
HDAC1 6791.0
H2BC5 6618.0
H2AZ2 6467.0
H2BC10 6026.0
CBX3 5646.0
H3C11 5197.0
H2BC15 4475.0
MTA3 3682.0
H2BC8 3188.0
H2AC8 3039.0
H4C16 2382.0
GATAD2B 2336.0
H3C3 2303.0
ERCC6 1693.0
H4C2 1279.0
H4C11 1080.0
H2BC13 823.0
MBD3 347.0
H4C6 -340.0
RBBP4 -414.0
CHD4 -663.0
CHD3 -1071.0
H2BC12 -1288.0
H2AZ1 -1561.0
H2BC4 -2033.0
H3C10 -2100.0
MTA2 -2122.0
H4C13 -2348.0
EHMT2 -2398.0
H4C12 -2774.0
H4C9 -3283.0
H2AC6 -3373.0
H4C5 -4637.0
H4C4 -4917.0
H2AX -5114.0
H2BC11 -5816.0
H2BC26 -6669.0
H2BC1 -7617.0
MTA1 -8549.0
GATAD2A -8692.0



REACTOME_MRNA_SPLICING

REACTOME_MRNA_SPLICING
1143
set REACTOME_MRNA_SPLICING
setSize 197
pANOVA 3.77e-06
s.dist 0.191
p.adjustANOVA 0.000138



Top enriched genes

Top 20 genes
GeneID Gene Rank
ZMAT2 10172
PHF5A 10133
CWC15 9904
SNRPD2 9776
SNU13 9681
SNRPA 9631
SNRPF 9329
POLR2K 9241
RBM8A 9140
ISY1 9061
RBM39 9022
LUC7L3 9021
PRPF4 8965
POLR2C 8943
SNRPD3 8937
HSPA8 8896
TXNL4A 8857
HNRNPA1 8761
PPIL3 8750
CRNKL1 8699

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ZMAT2 10172
PHF5A 10133
CWC15 9904
SNRPD2 9776
SNU13 9681
SNRPA 9631
SNRPF 9329
POLR2K 9241
RBM8A 9140
ISY1 9061
RBM39 9022
LUC7L3 9021
PRPF4 8965
POLR2C 8943
SNRPD3 8937
HSPA8 8896
TXNL4A 8857
HNRNPA1 8761
PPIL3 8750
CRNKL1 8699
SNW1 8694
SF3B5 8644
FUS 8636
HNRNPC 8571
LENG1 8570
YBX1 8540
LSM7 8523
PRKRIP1 8517
SRSF1 8484
SRSF8 8381
WBP11 8200
POLR2D 8181
SF3B4 8174
USP39 8048
HNRNPL 7999
CDC40 7861
FAM32A 7860
PPWD1 7797
PTBP1 7790
PCBP1 7777
DDX46 7661
C9orf78 7600
LSM4 7420
SRSF3 7367
ZCRB1 7361
PDCD7 7359
DHX9 7301
SNRNP25 7151
UBL5 6954
SF3A3 6945
BUD31 6756
PRPF19 6637
SRSF6 6524
GTF2F1 6376
RBM22 6365
EFTUD2 6296
ZNF830 6157
HNRNPU 6103
LSM8 6079
POLR2I 6073
ALYREF 5973
DHX35 5958
SNRPG 5906
LSM5 5866
GCFC2 5816
CWC25 5724
HNRNPK 5648
SF3A2 5551
WBP4 5549
BCAS2 5290
HNRNPA2B1 5128
DDX23 5098
IK 5064
POLR2H 4937
CCAR1 4859
HNRNPD 4808
SRSF11 4767
NCBP2 4667
LSM2 4624
PRPF38A 4451
CWC27 4299
SRSF2 4267
SRSF7 4237
SNRPE 4155
SMU1 3766
PCBP2 3688
SMNDC1 3686
SYF2 3587
PNN 3569
HNRNPR 3489
SF3B6 3468
SNRNP48 3372
POLR2B 3342
U2AF1L4 3251
PPIL1 3187
RBM7 3042
DDX41 2879
POLR2G 2774
SF3B3 2523
HNRNPA3 2501
MAGOHB 2447
DDX39B 2385
GTF2F2 2212
U2SURP 2211
SRSF10 2060
SDE2 1962
DDX42 1916
POLR2E 1875
DHX8 1752
TRA2B 1749
LSM6 1612
SNRPN 1552
SF1 1544
CCDC12 1534
SAP18 1491
SRSF5 1443
MAGOH 1349
SNIP1 1257
PPIH 1205
BUD13 1064
SRRM1 1034
PRPF31 995
PRPF40A 918
HNRNPM 859
SF3B1 782
HNRNPH1 534
ZMAT5 484
RBM25 456
RBM17 362
SNRNP35 -88
SLU7 -122
SRRT -154
DHX16 -264
HNRNPF -288
DDX5 -377
SNRPA1 -644
SNRPD1 -647
PLRG1 -915
PRPF18 -978
EIF4A3 -993
SF3B2 -995
CACTIN -1253
CDC5L -1498
LSM3 -1616
WDR70 -2238
MFAP1 -2278
SNRNP40 -2363
ACIN1 -2405
SNRPB2 -2424
RNPC3 -2497
RBM5 -2548
TFIP11 -2728
DNAJC8 -2749
AQR -2768
NCBP1 -3261
SNRPC -3551
DHX15 -3617
SNRPB -3828
DHX38 -3833
POLR2F -3844
PRPF8 -3970
POLR2L -4399
CWF19L2 -4566
PRCC -5135
RBM42 -5162
SRSF9 -5277
SNRNP27 -5486
PPIG -5700
MTREX -5758
SF3A1 -6066
TCERG1 -6336
XAB2 -6417
RNPS1 -6758
PRPF6 -6865
CWC22 -6935
SRSF12 -6979
CASC3 -7100
PPIL4 -7129
SRRM2 -7130
SNRNP200 -7137
PUF60 -7159
SRSF4 -7270
POLR2J -7312
NSRP1 -7471
POLR2A -7563
PPP1R8 -7777
PPIE -8126
U2AF2 -8312
SNRNP70 -8629
SUGP1 -8744
YJU2 -8859
CTNNBL1 -9023
PRPF3 -9233
CHERP -9359
PPIL2 -9370
GPATCH1 -9589
SART1 -9806



REACTOME_SENESCENCE_ASSOCIATED_SECRETORY_PHENOTYPE_SASP

REACTOME_SENESCENCE_ASSOCIATED_SECRETORY_PHENOTYPE_SASP
502
set REACTOME_SENESCENCE_ASSOCIATED_SECRETORY_PHENOTYPE_SASP
setSize 104
pANOVA 3.96e-06
s.dist 0.262
p.adjustANOVA 0.000141



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C12 10715
H2BC14 10635
H2AC14 10619
H2BC6 10447
H2BC17 10375
H4C1 10268
H2AC4 10244
H3C1 10183
H3C6 9987
UBE2S 9716
H3C2 9609
FOS 9527
CDK4 9521
JUN 9518
H3C8 9237
H2AJ 9219
CDC26 9208
IL6 8975
CDKN2B 8957
H4C3 8934

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
H4C1 10268.0
H2AC4 10244.0
H3C1 10183.0
H3C6 9987.0
UBE2S 9716.0
H3C2 9609.0
FOS 9527.0
CDK4 9521.0
JUN 9518.0
H3C8 9237.0
H2AJ 9219.0
CDC26 9208.0
IL6 8975.0
CDKN2B 8957.0
H4C3 8934.0
H4C8 8774.0
H2AC20 8751.0
IL1A 8541.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0
H2BC9 7978.5
H3C7 7978.5
H2BC21 7828.0
CEBPB 7763.0
ANAPC11 7732.0
RPS27A 7698.0
H2AC18 7550.5
H2AC19 7550.5
UBB 7319.0
H3C4 7298.0
H2BC3 6830.0
CDC16 6674.0
H2BC5 6618.0
CDKN2D 6595.0
H2AZ2 6467.0
ANAPC16 6333.0
H2BC10 6026.0
NFKB1 5873.0
STAT3 5799.0
H3C11 5197.0
H2BC15 4475.0
CDC23 3912.0
ANAPC10 3818.0
CDK2 3557.0
H2BC8 3188.0
H2AC8 3039.0
CDKN2A 2953.0
RELA 2935.0
ANAPC4 2868.0
ANAPC1 2721.0
H4C16 2382.0
H3C3 2303.0
H4C2 1279.0
H4C11 1080.0
H2BC13 823.0
CDC27 89.0
ANAPC7 43.0
CDKN2C -189.0
UBE2E1 -331.0
H4C6 -340.0
CDKN1B -509.0
UBC -640.0
CDKN1A -800.0
CCNA1 -892.0
H2BC12 -1288.0
H2AZ1 -1561.0
MAPK7 -1772.0
H2BC4 -2033.0
CDK6 -2037.0
H3C10 -2100.0
H4C13 -2348.0
EHMT2 -2398.0
H4C12 -2774.0
UBE2C -2846.0
UBA52 -2875.0
RPS6KA2 -2916.0
ANAPC5 -3127.0
H4C9 -3283.0
H2AC6 -3373.0
EHMT1 -3490.0
CCNA2 -3622.0
H4C5 -4637.0
H4C4 -4917.0
H2AX -5114.0
ANAPC15 -5225.0
H2BC11 -5816.0
VENTX -6394.0
H2BC26 -6669.0
MAPK1 -6741.0
IGFBP7 -6938.0
RPS6KA1 -7053.0
UBE2D1 -7157.0
CXCL8 -7325.0
FZR1 -7345.0
MAPK3 -7453.0
H2BC1 -7617.0
ANAPC2 -9497.0



REACTOME_SELENOAMINO_ACID_METABOLISM

REACTOME_SELENOAMINO_ACID_METABOLISM
484
set REACTOME_SELENOAMINO_ACID_METABOLISM
setSize 108
pANOVA 5.14e-06
s.dist 0.254
p.adjustANOVA 0.00018



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS5 10401
RPL39L 10015
RPS13 10010
HNMT 9767
RPLP0 9720
RPL27 9406
RPL6 9269
AHCY 9217
RPL27A 8979
RPS28 8978
RPS8 8920
RPS12 8794
RPS25 8638
RPL19 8597
RPL9 8592
RPL12 8542
RPS6 8501
RPL41 8240
RPL18 8234
RPL10A 8175

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS5 10401.0
RPL39L 10015.0
RPS13 10010.0
HNMT 9767.0
RPLP0 9720.0
RPL27 9406.0
RPL6 9269.0
AHCY 9217.0
RPL27A 8979.0
RPS28 8978.0
RPS8 8920.0
RPS12 8794.0
RPS25 8638.0
RPL19 8597.0
RPL9 8592.0
RPL12 8542.0
RPS6 8501.0
RPL41 8240.0
RPL18 8234.0
RPL10A 8175.0
RPS2 8109.0
FAU 8086.0
RPL5 8055.0
RPL36AL 8033.5
RPS3A 7941.0
RPL23 7907.0
RPS18 7868.0
RPL13 7712.0
RPS27A 7698.0
RPL13A 7489.5
RPLP2 7348.0
RPL3 7194.0
RPL4 7148.0
RPS26 6957.0
RPL38 6914.0
RPS21 6901.0
RPL35A 6893.0
RPL21 6804.0
LARS1 6527.0
RPL28 6441.0
RPL34 6124.0
RPL7 6080.0
RPL17 6034.0
RPS29 5882.0
RPS15 5697.0
RPL18A 5467.0
RPL32 5357.0
RPS15A 5210.0
RPS10 5051.0
RPS19 5043.0
RPL35 4765.0
RPS20 4727.0
RPSA 3658.0
IARS1 3426.0
RPL26L1 3215.0
RPL8 3119.0
KARS1 2797.0
RPS24 2748.0
RPL30 2631.0
RPL37 2527.0
RPS16 2475.0
RPL11 2329.0
RPS27L 2308.0
RPS23 2004.0
PAPSS2 1838.0
TXNRD1 1836.0
EEF1E1 1616.0
RARS1 1516.0
RPL36 1365.0
RPS11 1269.0
RPS27 1132.0
RPLP1 792.0
RPL22 440.0
RPS14 322.0
RPL24 57.0
RPL14 -57.0
SEPHS2 -594.0
RPS3 -850.0
CTH -859.0
GNMT -900.0
RPL23A -1287.0
RPL15 -1589.0
SEPSECS -1608.0
RPS9 -1972.0
MAT1A -2137.0
EPRS1 -2577.0
UBA52 -2875.0
AIMP1 -3384.0
RPS7 -3608.0
DARS1 -3941.0
GSR -4493.0
RPL3L -4519.0
RPL29 -4767.0
SECISBP2 -5468.0
RPL37A -5673.0
RPL7A -5783.0
MARS1 -6171.0
RPL22L1 -6323.0
RPL26 -6909.0
SCLY -6984.0
EEFSEC -7338.0
NNMT -7389.0
AIMP2 -8214.0
RPL31 -8668.0
PAPSS1 -8987.0
PSTK -9316.0
INMT -9935.0
RPL10L -10702.0



REACTOME_CONDENSATION_OF_PROPHASE_CHROMOSOMES

REACTOME_CONDENSATION_OF_PROPHASE_CHROMOSOMES
480
set REACTOME_CONDENSATION_OF_PROPHASE_CHROMOSOMES
setSize 66
pANOVA 5.41e-06
s.dist 0.324
p.adjustANOVA 0.000185



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
H4C1 10268.0
H2AC4 10244.0
SET 10185.0
H3C1 10183.0
H3C6 9987.0
H3C2 9609.0
H3C8 9237.0
H2AJ 9219.0
H4C3 8934.0
H4C8 8774.0
H2AC20 8751.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
H4C1 10268.0
H2AC4 10244.0
SET 10185.0
H3C1 10183.0
H3C6 9987.0
H3C2 9609.0
H3C8 9237.0
H2AJ 9219.0
H4C3 8934.0
H4C8 8774.0
H2AC20 8751.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0
H2BC9 7978.5
H3C7 7978.5
RB1 7836.0
H2BC21 7828.0
H2AC18 7550.5
H2AC19 7550.5
PLK1 7394.0
CDK1 7383.0
H3C4 7298.0
H2BC3 6830.0
H2BC5 6618.0
H2AZ2 6467.0
H2BC10 6026.0
H3C11 5197.0
H2BC15 4475.0
H2BC8 3188.0
H2AC8 3039.0
H4C16 2382.0
H3C3 2303.0
H4C2 1279.0
H4C11 1080.0
H2BC13 823.0
H4C6 -340.0
NCAPD3 -467.0
CCNB1 -600.0
H2BC12 -1288.0
SMC4 -1405.0
H2AZ1 -1561.0
H2BC4 -2033.0
H3C10 -2100.0
H4C13 -2348.0
H4C12 -2774.0
SMC2 -3038.0
KMT5A -3229.0
H4C9 -3283.0
NCAPG2 -3295.0
H2AC6 -3373.0
H4C5 -4637.0
H4C4 -4917.0
H2AX -5114.0
H2BC11 -5816.0
NCAPH2 -5925.0
H2BC26 -6669.0
H3-4 -6761.0
MCPH1 -7094.0
H2BC1 -7617.0



REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS

REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS
901
set REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS
setSize 113
pANOVA 5.9e-06
s.dist 0.247
p.adjustANOVA 0.000197



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C12 10715
H2BC14 10635
H2AC14 10619
H2BC6 10447
H2BC17 10375
H4C1 10268
H2AC4 10244
H3C1 10183
H3C6 9987
H3C2 9609
JUN 9518
HOXA2 9480
HOXA1 9310
POLR2K 9241
H3C8 9237
H2AJ 9219
HOXC4 9189
POLR2C 8943
H4C3 8934
H4C8 8774

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C12 10715.0
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
H4C1 10268.0
H2AC4 10244.0
H3C1 10183.0
H3C6 9987.0
H3C2 9609.0
JUN 9518.0
HOXA2 9480.0
HOXA1 9310.0
POLR2K 9241.0
H3C8 9237.0
H2AJ 9219.0
HOXC4 9189.0
POLR2C 8943.0
H4C3 8934.0
H4C8 8774.0
H2AC20 8751.0
H3-3A 8367.0
H2AC7 8363.5
H2BC7 8363.5
H3-3B 8344.0
POLR2D 8181.0
H2BC9 7978.5
H3C7 7978.5
RBBP5 7851.0
H2BC21 7828.0
AJUBA 7627.0
PIAS2 7622.0
H2AC18 7550.5
H2AC19 7550.5
RARA 7478.0
H3C4 7298.0
H2BC3 6830.0
H2BC5 6618.0
HOXB2 6602.0
H2AZ2 6467.0
YY1 6328.0
CNOT9 6134.0
CNOT6 6096.0
POLR2I 6073.0
H2BC10 6026.0
EGR2 5517.0
H3C11 5197.0
HOXD1 5099.0
POLR2H 4937.0
H2BC15 4475.0
HOXD4 4307.0
PAX6 3835.0
ZNF335 3641.0
MAFB 3526.0
POLR2B 3342.0
H2BC8 3188.0
H2AC8 3039.0
POLR2G 2774.0
HOXB3 2636.0
H4C16 2382.0
PAGR1 2310.0
H3C3 2303.0
POLR2E 1875.0
PAXIP1 1319.0
H4C2 1279.0
H4C11 1080.0
RARG 986.0
H2BC13 823.0
CTCF 473.0
KMT2C 331.0
PCGF2 -220.0
HOXB4 -222.0
RXRA -296.0
H4C6 -340.0
RBBP4 -414.0
RARB -949.0
EP300 -1043.0
SUZ12 -1050.0
NCOA6 -1244.0
H2BC12 -1288.0
H2AZ1 -1561.0
HOXD3 -1823.0
H2BC4 -2033.0
H3C10 -2100.0
HDAC3 -2207.0
H4C13 -2348.0
NCOA3 -2550.0
ASH2L -2601.0
HOXA3 -2658.0
H4C12 -2774.0
H4C9 -3283.0
H2AC6 -3373.0
EZH2 -3560.0
EED -3682.0
NCOR1 -3721.0
POLR2F -3844.0
PBX1 -4130.0
PKNOX1 -4318.0
POLR2L -4399.0
H4C5 -4637.0
H4C4 -4917.0
H2AX -5114.0
HOXA4 -5312.0
H2BC11 -5816.0
MEIS1 -6639.0
H2BC26 -6669.0
CREBBP -7206.0
POLR2J -7312.0
POLR2A -7563.0
H2BC1 -7617.0
KMT2D -9368.0
HOXB1 -9606.0
WDR5 -9985.0



REACTOME_DEUBIQUITINATION

REACTOME_DEUBIQUITINATION
1000
set REACTOME_DEUBIQUITINATION
setSize 260
pANOVA 5.99e-06
s.dist 0.163
p.adjustANOVA 0.000197



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2BC14 10635
H2AC14 10619
H2BC6 10447
H2BC17 10375
H2AC4 10244
ACTB 10161
TAF10 10038
PSMB8 9883
DDB2 9626
NEDD8 9459
PSMC1 9440
TOMM70 9433
SMAD4 9393
GATA3 9341
ASXL1 9181
MDM2 9066
TOMM20 9058
NFKBIA 9057
H2AC20 8751
H2AC17 8748

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2BC14 10635.0
H2AC14 10619.0
H2BC6 10447.0
H2BC17 10375.0
H2AC4 10244.0
ACTB 10161.0
TAF10 10038.0
PSMB8 9883.0
DDB2 9626.0
NEDD8 9459.0
PSMC1 9440.0
TOMM70 9433.0
SMAD4 9393.0
GATA3 9341.0
ASXL1 9181.0
MDM2 9066.0
TOMM20 9058.0
NFKBIA 9057.0
H2AC20 8751.0
H2AC17 8748.0
PSMD4 8637.0
PSME2 8563.0
PSMD7 8416.0
H2AC7 8363.5
H2BC7 8363.5
TP53 8272.0
USP44 8259.0
PSMB3 8251.0
SENP8 8229.0
CFTR 8134.0
H2BC9 7978.5
TGFBR2 7921.0
PSMC6 7899.0
JOSD1 7833.0
H2BC21 7828.0
USP14 7807.0
POLB 7793.0
INO80B 7767.0
RPS27A 7698.0
MYC 7649.0
MAVS 7593.0
H2AC18 7550.5
H2AC19 7550.5
H2AC15 7513.0
RAD23A 7399.0
CDK1 7383.0
UBB 7319.0
TNIP2 7098.0
PSMC3 7021.0
SKP2 7007.0
ACTR5 7003.0
IDE 6921.0
PSMB9 6881.0
H2BC3 6830.0
ABRAXAS1 6811.0
PSMA2 6802.0
TADA3 6774.0
INO80D 6724.0
H2BC5 6618.0
MDM4 6604.0
OTUB2 6575.0
HIF1A 6555.0
USP4 6519.0
YY1 6328.0
RAD23B 6250.0
USP33 6240.0
IFIH1 6187.0
SNX3 6166.0
TFPT 6158.0
USP2 6149.0
H2BC10 6026.0
UCHL5 6012.0
FKBP8 5951.0
PSMD12 5909.0
STAM2 5833.0
PSMA3 5797.0
PSMC2 5730.0
PSMA1 5699.0
ARRB2 5522.0
PSMB4 5511.0
SMAD2 5479.0
AXIN2 5460.0
PSMA7 5457.0
WDR48 5382.0
BECN1 5324.0
PSMC5 5252.0
SIAH2 5224.0
CDC20 5122.0
INO80E 5044.0
PSMA4 4968.0
USP10 4962.0
ADRB2 4919.0
USP16 4720.0
SUDS3 4716.0
USP48 4536.0
H2AC21 4518.0
BIRC3 4492.0
H2BC15 4475.0
MAT2B 4376.0
UFD1 4333.0
BIRC2 4294.0
ADRM1 4254.0
PSMD3 4188.0
MYSM1 4060.0
USP5 4004.0
ACTR8 3911.0
BARD1 3901.0
MBD6 3887.0
VDAC3 3652.0
PSMC4 3370.0
ASXL2 3282.0
PSMD1 3237.0
H2BC8 3188.0
ACTL6A 3151.0
CLSPN 3142.0
H2AC8 3039.0
USP21 3018.0
ABRAXAS2 2960.0
PSMD5 2770.0
KDM1B 2657.0
USP37 2628.0
RIGI 2552.0
USP18 2358.0
BRCA1 2223.0
PSMB10 2137.0
BABAM1 2098.0
H2AC13 1943.0
KAT2B 1876.0
VCPIP1 1812.0
TAB1 1806.0
ESR1 1723.0
PSMB1 1698.0
H2AC16 1647.0
PTRH2 1595.0
TNIP3 1389.0
UCHL3 1383.0
USP8 1356.0
MAP3K7 1330.0
PSMA8 1258.0
PSMD2 1209.0
SMAD1 1153.0
PSMD9 1039.0
RIPK2 982.0
H2BC13 823.0
NOD1 810.0
PSMD14 794.0
KEAP1 640.0
UIMC1 630.0
USP19 619.0
PTEN 429.0
PSMD11 411.0
PSMA5 410.0
H2AC12 395.0
TGFB1 382.0
CCP110 260.0
USP28 196.0
USP30 62.0
TRIM25 3.0
INO80C -6.0
PSMB5 -134.0
MUL1 -292.0
H2AC11 -408.0
TRAF3 -477.0
OTUD7B -529.0
CYLD -556.0
FOXK2 -571.0
UBC -640.0
USP25 -649.0
CCNA1 -892.0
STAM -957.0
EP300 -1043.0
NFRKB -1056.0
VDAC2 -1132.0
SMURF2 -1158.0
RNF146 -1194.0
PSMD13 -1223.0
H2BC12 -1288.0
TGFBR1 -1305.0
RHOT1 -1510.0
TNKS2 -1511.0
USP42 -1604.0
ARRB1 -1686.0
INO80 -1700.0
RCE1 -1711.0
SMAD7 -1829.0
YOD1 -1944.0
USP3 -2030.0
H2BC4 -2033.0
TNFAIP3 -2133.0
FOXK1 -2235.0
PSME3 -2265.0
USP49 -2321.0
KAT2A -2329.0
ATXN3 -2353.0
PRKN -2790.0
USP47 -2849.0
UBA52 -2875.0
IL33 -2922.0
PSMB7 -2995.0
UCHL1 -3040.0
PSME4 -3042.0
BABAM2 -3322.0
H2AC6 -3373.0
RUVBL1 -3452.0
VDAC1 -3519.0
CCNA2 -3622.0
USP7 -3676.0
TNIP1 -3699.0
VCP -3748.0
ATXN7 -3832.0
CDC25A -3836.0
PSMA6 -3897.0
MCRS1 -3950.0
USP22 -4125.0
NLRP3 -4141.0
OTUD7A -4179.0
RNF123 -4185.0
WDR20 -4215.0
PSMB2 -4270.0
HGS -4314.0
BAP1 -4394.0
JOSD2 -4466.0
USP20 -4507.0
RNF135 -4592.0
SEM1 -4777.0
TNKS -4895.0
STAMBP -4944.0
OTUB1 -4997.0
PSMD8 -5041.0
STAMBPL1 -5112.0
RHOA -5156.0
OTUD3 -5383.0
TRIM4 -5419.0
PSMF1 -5472.0
APC -5488.0
H2BC11 -5816.0
RIPK1 -5927.0
PSMD6 -5971.0
USP34 -6222.0
H2AC25 -6359.0
H2BC26 -6669.0
USP24 -6801.0
PSMB6 -6874.0
UBE2D1 -7157.0
H2AC1 -7358.0
SMAD3 -7379.0
USP12 -7429.0
H2BC1 -7617.0
TRAF2 -7698.0
TRAF6 -7812.0
PSME1 -8232.0
ZRANB1 -8262.0
MBD5 -8712.0
USP13 -8771.0
TRRAP -8866.0
PSMB11 -9151.0
USP15 -9503.0
NOD2 -9869.0
AXIN1 -10153.0
TADA2B -10229.0



Here is the session info with all the versions of packages used.

sessionInfo()
## R version 4.3.2 (2023-10-31)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.3 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3 
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so;  LAPACK version 3.10.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Etc/UTC
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.3.3                                      
##  [2] GGally_2.2.0                                       
##  [3] ggplot2_3.4.4                                      
##  [4] reshape2_1.4.4                                     
##  [5] gtools_3.9.5                                       
##  [6] tibble_3.2.1                                       
##  [7] dplyr_1.1.4                                        
##  [8] echarts4r_0.4.5                                    
##  [9] png_0.1-8                                          
## [10] gridExtra_2.3                                      
## [11] missMethyl_1.36.0                                  
## [12] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.1 
## [13] beeswarm_0.4.0                                     
## [14] kableExtra_1.3.4                                   
## [15] gplots_3.1.3                                       
## [16] mitch_1.15.0                                       
## [17] tictoc_1.2                                         
## [18] HGNChelper_0.8.1                                   
## [19] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [20] IlluminaHumanMethylation450kmanifest_0.4.0         
## [21] minfi_1.48.0                                       
## [22] bumphunter_1.44.0                                  
## [23] locfit_1.5-9.8                                     
## [24] iterators_1.0.14                                   
## [25] foreach_1.5.2                                      
## [26] Biostrings_2.70.1                                  
## [27] XVector_0.42.0                                     
## [28] SummarizedExperiment_1.32.0                        
## [29] Biobase_2.62.0                                     
## [30] MatrixGenerics_1.14.0                              
## [31] matrixStats_1.2.0                                  
## [32] GenomicRanges_1.54.1                               
## [33] GenomeInfoDb_1.38.2                                
## [34] IRanges_2.36.0                                     
## [35] S4Vectors_0.40.2                                   
## [36] BiocGenerics_0.48.1                                
## [37] eulerr_7.0.0                                       
## [38] limma_3.58.1                                       
## 
## loaded via a namespace (and not attached):
##   [1] splines_4.3.2             later_1.3.2              
##   [3] BiocIO_1.12.0             bitops_1.0-7             
##   [5] filelock_1.0.3            preprocessCore_1.64.0    
##   [7] XML_3.99-0.16             lifecycle_1.0.4          
##   [9] lattice_0.22-5            MASS_7.3-60              
##  [11] base64_2.0.1              scrime_1.3.5             
##  [13] magrittr_2.0.3            sass_0.4.8               
##  [15] rmarkdown_2.25            jquerylib_0.1.4          
##  [17] yaml_2.3.8                httpuv_1.6.13            
##  [19] doRNG_1.8.6               askpass_1.2.0            
##  [21] DBI_1.1.3                 RColorBrewer_1.1-3       
##  [23] abind_1.4-5               zlibbioc_1.48.0          
##  [25] rvest_1.0.3               quadprog_1.5-8           
##  [27] purrr_1.0.2               RCurl_1.98-1.13          
##  [29] rappdirs_0.3.3            GenomeInfoDbData_1.2.11  
##  [31] genefilter_1.84.0         annotate_1.80.0          
##  [33] svglite_2.1.3             DelayedMatrixStats_1.24.0
##  [35] codetools_0.2-19          DelayedArray_0.28.0      
##  [37] xml2_1.3.6                tidyselect_1.2.0         
##  [39] beanplot_1.3.1            BiocFileCache_2.10.1     
##  [41] webshot_0.5.5             illuminaio_0.44.0        
##  [43] GenomicAlignments_1.38.0  jsonlite_1.8.8           
##  [45] multtest_2.58.0           ellipsis_0.3.2           
##  [47] survival_3.5-7            systemfonts_1.0.5        
##  [49] tools_4.3.2               progress_1.2.3           
##  [51] Rcpp_1.0.11               glue_1.6.2               
##  [53] SparseArray_1.2.2         xfun_0.41                
##  [55] HDF5Array_1.30.0          withr_2.5.2              
##  [57] fastmap_1.1.1             rhdf5filters_1.14.1      
##  [59] fansi_1.0.6               openssl_2.1.1            
##  [61] caTools_1.18.2            digest_0.6.33            
##  [63] R6_2.5.1                  mime_0.12                
##  [65] colorspace_2.1-0          biomaRt_2.58.0           
##  [67] RSQLite_2.3.4             utf8_1.2.4               
##  [69] tidyr_1.3.0               generics_0.1.3           
##  [71] data.table_1.14.10        rtracklayer_1.62.0       
##  [73] prettyunits_1.2.0         httr_1.4.7               
##  [75] htmlwidgets_1.6.4         S4Arrays_1.2.0           
##  [77] ggstats_0.5.1             pkgconfig_2.0.3          
##  [79] gtable_0.3.4              blob_1.2.4               
##  [81] siggenes_1.76.0           htmltools_0.5.7          
##  [83] scales_1.3.0              rstudioapi_0.15.0        
##  [85] knitr_1.45                tzdb_0.4.0               
##  [87] rjson_0.2.21              nlme_3.1-163             
##  [89] curl_5.2.0                org.Hs.eg.db_3.18.0      
##  [91] cachem_1.0.8              rhdf5_2.46.1             
##  [93] stringr_1.5.1             KernSmooth_2.23-22       
##  [95] AnnotationDbi_1.64.1      restfulr_0.0.15          
##  [97] GEOquery_2.70.0           pillar_1.9.0             
##  [99] grid_4.3.2                reshape_0.8.9            
## [101] vctrs_0.6.5               promises_1.2.1           
## [103] dbplyr_2.4.0              xtable_1.8-4             
## [105] evaluate_0.23             readr_2.1.4              
## [107] GenomicFeatures_1.54.1    cli_3.6.2                
## [109] compiler_4.3.2            Rsamtools_2.18.0         
## [111] rlang_1.1.2               crayon_1.5.2             
## [113] rngtools_1.5.2            nor1mix_1.3-2            
## [115] mclust_6.0.1              plyr_1.8.9               
## [117] stringi_1.8.3             viridisLite_0.4.2        
## [119] BiocParallel_1.36.0       munsell_0.5.0            
## [121] Matrix_1.6-1.1            hms_1.1.3                
## [123] sparseMatrixStats_1.14.0  bit64_4.0.5              
## [125] Rhdf5lib_1.24.1           KEGGREST_1.42.0          
## [127] statmod_1.5.0             shiny_1.8.0              
## [129] highr_0.10                memoise_2.0.1            
## [131] bslib_0.6.1               bit_4.0.5

END of report