Mitch Report
Antony Kaspi & Mark Ziemann
date generated: 2024-01-18
Background
Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch
Input profiles
Here is the first few lines of the input profile.
| x | |
|---|---|
| A1BG | -0.0082216 |
| A1BG-AS1 | -0.0042335 |
| A1CF | -0.0090028 |
| A2M | 0.0068207 |
| A2M-AS1 | 0.0612860 |
| A2ML1 | -0.0151427 |
Here are some metrics about the input data profile:
| Profile metrics | |
|---|---|
| num_genesets | 1654 |
| num_genes_in_profile | 22007 |
| duplicated_genes_present | 0 |
| num_profile_genes_in_sets | 10383 |
| num_profile_genes_not_in_sets | 11624 |
Here is a plot of the input profiles. Note the dynamic ranges.
Here is the contour plot of the profile including all detected genes.
Input genesets
Here are some metrics about the gene sets used:
GMT file of genesets: c2.cp.reactome.v2023.1.Hs.symbols.gmt| Gene sets metrics | |
|---|---|
| num_genesets | 1654 |
| num_genesets_excluded | 365 |
| num_genesets_included | 1289 |
Differential pathway expression
Interactive enrichment scatterplot
Significance is calculated by -log10(p-value). All points shown are
FDR<0.05.
Significance is calculated by -log10(p-value). Top N sets shown
irrespective of FDR.
Results table
Top N= 50 gene sets
## Warning in kable_styling(., "hover", full_width = FALSE): Please specify format
## in kable. kableExtra can customize either HTML or LaTeX outputs. See
## https://haozhu233.github.io/kableExtra/ for details.| set | setSize | pANOVA | s.dist | p.adjustANOVA |
|---|---|---|---|---|
| REACTOME INNATE IMMUNE SYSTEM | 1002 | 2.17e-07 | -0.0968 | 0.000351 |
| REACTOME NEUTROPHIL DEGRANULATION | 460 | 4.28e-07 | -0.1380 | 0.000351 |
| REACTOME RNA POLYMERASE II TRANSCRIPTION | 1336 | 4.38e-05 | 0.0666 | 0.024000 |
| REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS | 6 | 1.23e-04 | -0.9050 | 0.050700 |
| REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | 122 | 2.06e-04 | -0.1940 | 0.067800 |
| REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | 129 | 2.53e-04 | -0.1870 | 0.069400 |
| REACTOME FERTILIZATION | 26 | 4.45e-04 | -0.3980 | 0.104000 |
| REACTOME DEVELOPMENTAL BIOLOGY | 1115 | 5.87e-04 | -0.0610 | 0.121000 |
| REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | 105 | 1.00e-03 | -0.1860 | 0.183000 |
| REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION | 29 | 1.20e-03 | 0.3470 | 0.197000 |
| REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS | 161 | 1.39e-03 | -0.1460 | 0.208000 |
| REACTOME NERVOUS SYSTEM DEVELOPMENT | 552 | 1.66e-03 | -0.0783 | 0.228000 |
| REACTOME MTOR SIGNALLING | 40 | 2.20e-03 | 0.2800 | 0.277000 |
| REACTOME COMPLEMENT CASCADE | 54 | 2.61e-03 | -0.2370 | 0.306000 |
| REACTOME REGULATION OF PTEN GENE TRANSCRIPTION | 59 | 3.19e-03 | 0.2220 | 0.349000 |
| REACTOME DAP12 INTERACTIONS | 37 | 3.44e-03 | -0.2780 | 0.352000 |
| REACTOME EUKARYOTIC TRANSLATION ELONGATION | 87 | 3.64e-03 | -0.1800 | 0.352000 |
| REACTOME ANTIMICROBIAL PEPTIDES | 76 | 4.30e-03 | -0.1890 | 0.373000 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS | 9 | 4.43e-03 | 0.5480 | 0.373000 |
| REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS | 16 | 4.54e-03 | -0.4100 | 0.373000 |
| REACTOME SIGNALING BY ROBO RECEPTORS | 206 | 5.02e-03 | -0.1130 | 0.393000 |
| REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS | 42 | 5.33e-03 | -0.2480 | 0.393000 |
| REACTOME PROTEIN METHYLATION | 17 | 5.51e-03 | 0.3890 | 0.393000 |
| REACTOME NONSENSE MEDIATED DECAY NMD | 107 | 6.91e-03 | -0.1510 | 0.473000 |
| REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND | 21 | 7.37e-03 | -0.3380 | 0.480000 |
| REACTOME KERATINIZATION | 210 | 7.61e-03 | -0.1070 | 0.480000 |
| REACTOME SUMOYLATION | 179 | 8.41e-03 | 0.1140 | 0.511000 |
| REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING | 6 | 9.73e-03 | -0.6090 | 0.570000 |
| REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE | 277 | 1.06e-02 | 0.0892 | 0.598000 |
| REACTOME REPRODUCTION | 136 | 1.15e-02 | -0.1250 | 0.598000 |
| REACTOME MEMBRANE TRAFFICKING | 603 | 1.19e-02 | 0.0600 | 0.598000 |
| REACTOME AMYLOID FIBER FORMATION | 102 | 1.24e-02 | -0.1430 | 0.598000 |
| REACTOME ANTIGEN PROCESSING CROSS PRESENTATION | 98 | 1.25e-02 | -0.1460 | 0.598000 |
| REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS | 8 | 1.27e-02 | 0.5090 | 0.598000 |
| REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG | 7 | 1.27e-02 | 0.5440 | 0.598000 |
| REACTOME TRANSCRIPTIONAL REGULATION BY VENTX | 41 | 1.37e-02 | 0.2220 | 0.616000 |
| REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS | 11 | 1.39e-02 | 0.4280 | 0.616000 |
| REACTOME TRANSLATION | 278 | 1.51e-02 | -0.0847 | 0.623000 |
| REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK | 28 | 1.56e-02 | 0.2640 | 0.623000 |
| REACTOME ERYTHROPOIETIN ACTIVATES STAT5 | 7 | 1.57e-02 | 0.5270 | 0.623000 |
| REACTOME TYROSINE CATABOLISM | 5 | 1.59e-02 | -0.6230 | 0.623000 |
| REACTOME EUKARYOTIC TRANSLATION INITIATION | 110 | 1.59e-02 | -0.1330 | 0.623000 |
| REACTOME INTERFERON ALPHA BETA SIGNALING | 70 | 1.72e-02 | 0.1650 | 0.657000 |
| REACTOME HEME SIGNALING | 47 | 1.91e-02 | 0.1980 | 0.700000 |
| REACTOME CILIUM ASSEMBLY | 190 | 1.97e-02 | 0.0981 | 0.700000 |
| REACTOME MET ACTIVATES PI3K AKT SIGNALING | 6 | 1.98e-02 | -0.5490 | 0.700000 |
| REACTOME ABC TRANSPORTER DISORDERS | 76 | 2.02e-02 | -0.1540 | 0.700000 |
| REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION | 45 | 2.11e-02 | 0.1990 | 0.700000 |
| REACTOME DAP12 SIGNALING | 27 | 2.16e-02 | -0.2550 | 0.700000 |
| REACTOME DNA REPAIR | 321 | 2.17e-02 | 0.0745 | 0.700000 |
Results (complete table)
Click HERE to show results for all gene sets
| set | setSize | pANOVA | s.dist | p.adjustANOVA |
|---|---|---|---|---|
| REACTOME INNATE IMMUNE SYSTEM | 1002 | 2.17e-07 | -9.68e-02 | 0.000351 |
| REACTOME NEUTROPHIL DEGRANULATION | 460 | 4.28e-07 | -1.38e-01 | 0.000351 |
| REACTOME RNA POLYMERASE II TRANSCRIPTION | 1336 | 4.38e-05 | 6.66e-02 | 0.024000 |
| REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS | 6 | 1.23e-04 | -9.05e-01 | 0.050700 |
| REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | 122 | 2.06e-04 | -1.94e-01 | 0.067800 |
| REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | 129 | 2.53e-04 | -1.87e-01 | 0.069400 |
| REACTOME FERTILIZATION | 26 | 4.45e-04 | -3.98e-01 | 0.104000 |
| REACTOME DEVELOPMENTAL BIOLOGY | 1115 | 5.87e-04 | -6.10e-02 | 0.121000 |
| REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | 105 | 1.00e-03 | -1.86e-01 | 0.183000 |
| REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION | 29 | 1.20e-03 | 3.47e-01 | 0.197000 |
| REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS | 161 | 1.39e-03 | -1.46e-01 | 0.208000 |
| REACTOME NERVOUS SYSTEM DEVELOPMENT | 552 | 1.66e-03 | -7.83e-02 | 0.228000 |
| REACTOME MTOR SIGNALLING | 40 | 2.20e-03 | 2.80e-01 | 0.277000 |
| REACTOME COMPLEMENT CASCADE | 54 | 2.61e-03 | -2.37e-01 | 0.306000 |
| REACTOME REGULATION OF PTEN GENE TRANSCRIPTION | 59 | 3.19e-03 | 2.22e-01 | 0.349000 |
| REACTOME DAP12 INTERACTIONS | 37 | 3.44e-03 | -2.78e-01 | 0.352000 |
| REACTOME EUKARYOTIC TRANSLATION ELONGATION | 87 | 3.64e-03 | -1.80e-01 | 0.352000 |
| REACTOME ANTIMICROBIAL PEPTIDES | 76 | 4.30e-03 | -1.89e-01 | 0.373000 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS | 9 | 4.43e-03 | 5.48e-01 | 0.373000 |
| REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS | 16 | 4.54e-03 | -4.10e-01 | 0.373000 |
| REACTOME SIGNALING BY ROBO RECEPTORS | 206 | 5.02e-03 | -1.13e-01 | 0.393000 |
| REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS | 42 | 5.33e-03 | -2.48e-01 | 0.393000 |
| REACTOME PROTEIN METHYLATION | 17 | 5.51e-03 | 3.89e-01 | 0.393000 |
| REACTOME NONSENSE MEDIATED DECAY NMD | 107 | 6.91e-03 | -1.51e-01 | 0.473000 |
| REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND | 21 | 7.37e-03 | -3.38e-01 | 0.480000 |
| REACTOME KERATINIZATION | 210 | 7.61e-03 | -1.07e-01 | 0.480000 |
| REACTOME SUMOYLATION | 179 | 8.41e-03 | 1.14e-01 | 0.511000 |
| REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING | 6 | 9.73e-03 | -6.09e-01 | 0.570000 |
| REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE | 277 | 1.06e-02 | 8.92e-02 | 0.598000 |
| REACTOME REPRODUCTION | 136 | 1.15e-02 | -1.25e-01 | 0.598000 |
| REACTOME MEMBRANE TRAFFICKING | 603 | 1.19e-02 | 6.00e-02 | 0.598000 |
| REACTOME AMYLOID FIBER FORMATION | 102 | 1.24e-02 | -1.43e-01 | 0.598000 |
| REACTOME ANTIGEN PROCESSING CROSS PRESENTATION | 98 | 1.25e-02 | -1.46e-01 | 0.598000 |
| REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS | 8 | 1.27e-02 | 5.09e-01 | 0.598000 |
| REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG | 7 | 1.27e-02 | 5.44e-01 | 0.598000 |
| REACTOME TRANSCRIPTIONAL REGULATION BY VENTX | 41 | 1.37e-02 | 2.22e-01 | 0.616000 |
| REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS | 11 | 1.39e-02 | 4.28e-01 | 0.616000 |
| REACTOME TRANSLATION | 278 | 1.51e-02 | -8.47e-02 | 0.623000 |
| REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK | 28 | 1.56e-02 | 2.64e-01 | 0.623000 |
| REACTOME ERYTHROPOIETIN ACTIVATES STAT5 | 7 | 1.57e-02 | 5.27e-01 | 0.623000 |
| REACTOME TYROSINE CATABOLISM | 5 | 1.59e-02 | -6.23e-01 | 0.623000 |
| REACTOME EUKARYOTIC TRANSLATION INITIATION | 110 | 1.59e-02 | -1.33e-01 | 0.623000 |
| REACTOME INTERFERON ALPHA BETA SIGNALING | 70 | 1.72e-02 | 1.65e-01 | 0.657000 |
| REACTOME HEME SIGNALING | 47 | 1.91e-02 | 1.98e-01 | 0.700000 |
| REACTOME CILIUM ASSEMBLY | 190 | 1.97e-02 | 9.81e-02 | 0.700000 |
| REACTOME MET ACTIVATES PI3K AKT SIGNALING | 6 | 1.98e-02 | -5.49e-01 | 0.700000 |
| REACTOME ABC TRANSPORTER DISORDERS | 76 | 2.02e-02 | -1.54e-01 | 0.700000 |
| REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION | 45 | 2.11e-02 | 1.99e-01 | 0.700000 |
| REACTOME DAP12 SIGNALING | 27 | 2.16e-02 | -2.55e-01 | 0.700000 |
| REACTOME DNA REPAIR | 321 | 2.17e-02 | 7.45e-02 | 0.700000 |
| REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS | 15 | 2.33e-02 | -3.38e-01 | 0.700000 |
| REACTOME SCAVENGING BY CLASS A RECEPTORS | 19 | 2.34e-02 | -3.00e-01 | 0.700000 |
| REACTOME CHREBP ACTIVATES METABOLIC GENE EXPRESSION | 8 | 2.44e-02 | 4.60e-01 | 0.700000 |
| REACTOME HEMOSTASIS | 591 | 2.44e-02 | -5.42e-02 | 0.700000 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS | 7 | 2.47e-02 | 4.90e-01 | 0.700000 |
| REACTOME BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA | 5 | 2.48e-02 | 5.80e-01 | 0.700000 |
| REACTOME MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS | 7 | 2.61e-02 | 4.86e-01 | 0.700000 |
| REACTOME BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA | 5 | 2.64e-02 | 5.73e-01 | 0.700000 |
| REACTOME CALCITONIN LIKE LIGAND RECEPTORS | 10 | 2.71e-02 | -4.04e-01 | 0.700000 |
| REACTOME SENSORY PERCEPTION OF TASTE | 47 | 2.72e-02 | 1.86e-01 | 0.700000 |
| REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21 | 59 | 2.79e-02 | -1.66e-01 | 0.700000 |
| REACTOME NEGATIVE REGULATION OF NOTCH4 SIGNALING | 53 | 2.81e-02 | -1.74e-01 | 0.700000 |
| REACTOME TYSND1 CLEAVES PEROXISOMAL PROTEINS | 7 | 2.81e-02 | 4.79e-01 | 0.700000 |
| REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | 91 | 2.82e-02 | 1.33e-01 | 0.700000 |
| REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY | 33 | 2.82e-02 | -2.21e-01 | 0.700000 |
| REACTOME HEDGEHOG LIGAND BIOGENESIS | 64 | 2.85e-02 | -1.58e-01 | 0.700000 |
| REACTOME IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS | 17 | 2.86e-02 | 3.07e-01 | 0.700000 |
| REACTOME SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS | 74 | 2.90e-02 | 1.47e-01 | 0.700000 |
| REACTOME OLFACTORY SIGNALING PATHWAY | 348 | 3.14e-02 | -6.71e-02 | 0.713000 |
| REACTOME DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM | 38 | 3.15e-02 | -2.02e-01 | 0.713000 |
| REACTOME CARDIAC CONDUCTION | 125 | 3.19e-02 | -1.11e-01 | 0.713000 |
| REACTOME EXTRACELLULAR MATRIX ORGANIZATION | 291 | 3.20e-02 | -7.30e-02 | 0.713000 |
| REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | 39 | 3.27e-02 | 1.98e-01 | 0.713000 |
| REACTOME ORC1 REMOVAL FROM CHROMATIN | 70 | 3.29e-02 | -1.47e-01 | 0.713000 |
| REACTOME TRANSCRIPTIONAL REGULATION BY TP53 | 351 | 3.30e-02 | 6.62e-02 | 0.713000 |
| REACTOME AUTOPHAGY | 144 | 3.34e-02 | 1.03e-01 | 0.713000 |
| REACTOME CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER | 25 | 3.34e-02 | 2.46e-01 | 0.713000 |
| REACTOME BETA OXIDATION OF BUTANOYL COA TO ACETYL COA | 5 | 3.56e-02 | 5.43e-01 | 0.737000 |
| REACTOME MITOCHONDRIAL PROTEIN IMPORT | 58 | 3.59e-02 | -1.59e-01 | 0.737000 |
| REACTOME REGULATION OF RUNX3 EXPRESSION AND ACTIVITY | 54 | 3.59e-02 | -1.65e-01 | 0.737000 |
| REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE | 9 | 3.64e-02 | -4.03e-01 | 0.738000 |
| REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION | 6 | 3.74e-02 | -4.91e-01 | 0.743000 |
| REACTOME MUCOPOLYSACCHARIDOSES | 10 | 3.80e-02 | 3.79e-01 | 0.743000 |
| REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY | 26 | 3.89e-02 | 2.34e-01 | 0.743000 |
| REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | 9 | 3.95e-02 | 3.96e-01 | 0.743000 |
| REACTOME STABILIZATION OF P53 | 56 | 3.99e-02 | -1.59e-01 | 0.743000 |
| REACTOME FIBRONECTIN MATRIX FORMATION | 6 | 4.02e-02 | -4.84e-01 | 0.743000 |
| REACTOME PHASE 3 RAPID REPOLARISATION | 8 | 4.08e-02 | -4.18e-01 | 0.743000 |
| REACTOME BH3 ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI APOPTOTIC BCL 2 MEMBERS | 9 | 4.11e-02 | -3.93e-01 | 0.743000 |
| REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY | 94 | 4.13e-02 | -1.22e-01 | 0.743000 |
| REACTOME DSCAM INTERACTIONS | 11 | 4.15e-02 | -3.55e-01 | 0.743000 |
| REACTOME SEMAPHORIN INTERACTIONS | 61 | 4.16e-02 | -1.51e-01 | 0.743000 |
| REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES | 78 | 4.25e-02 | 1.33e-01 | 0.748000 |
| REACTOME TERMINAL PATHWAY OF COMPLEMENT | 8 | 4.28e-02 | -4.14e-01 | 0.748000 |
| REACTOME PKMTS METHYLATE HISTONE LYSINES | 64 | 4.40e-02 | 1.46e-01 | 0.754000 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS | 121 | 4.41e-02 | -1.06e-01 | 0.754000 |
| REACTOME RAC3 GTPASE CYCLE | 85 | 4.53e-02 | 1.26e-01 | 0.756000 |
| REACTOME RHOQ GTPASE CYCLE | 57 | 4.55e-02 | 1.53e-01 | 0.756000 |
| REACTOME MET ACTIVATES PTK2 SIGNALING | 30 | 4.56e-02 | -2.11e-01 | 0.756000 |
| REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE | 93 | 4.62e-02 | 1.20e-01 | 0.758000 |
| REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA | 11 | 4.68e-02 | -3.46e-01 | 0.761000 |
| REACTOME STAT3 NUCLEAR EVENTS DOWNSTREAM OF ALK SIGNALING | 9 | 4.81e-02 | 3.80e-01 | 0.775000 |
| REACTOME CELL CYCLE | 666 | 4.95e-02 | 4.46e-02 | 0.784000 |
| REACTOME PROLACTIN RECEPTOR SIGNALING | 15 | 5.04e-02 | 2.92e-01 | 0.784000 |
| REACTOME DEGRADATION OF GLI1 BY THE PROTEASOME | 59 | 5.13e-02 | -1.47e-01 | 0.784000 |
| REACTOME THE PHOTOTRANSDUCTION CASCADE | 32 | 5.15e-02 | 1.99e-01 | 0.784000 |
| REACTOME EPHA MEDIATED GROWTH CONE COLLAPSE | 29 | 5.16e-02 | 2.09e-01 | 0.784000 |
| REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | 11 | 5.21e-02 | -3.38e-01 | 0.784000 |
| REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS | 68 | 5.26e-02 | 1.36e-01 | 0.784000 |
| REACTOME G1 S DNA DAMAGE CHECKPOINTS | 67 | 5.32e-02 | -1.37e-01 | 0.784000 |
| REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS | 60 | 5.37e-02 | -1.44e-01 | 0.784000 |
| REACTOME TRANSCRIPTIONAL REGULATION BY MECP2 | 60 | 5.37e-02 | 1.44e-01 | 0.784000 |
| REACTOME MAP2K AND MAPK ACTIVATION | 38 | 5.40e-02 | -1.81e-01 | 0.784000 |
| REACTOME TRNA MODIFICATION IN THE MITOCHONDRION | 8 | 5.45e-02 | 3.93e-01 | 0.785000 |
| REACTOME CHROMATIN MODIFYING ENZYMES | 252 | 5.59e-02 | 6.99e-02 | 0.796000 |
| REACTOME AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA | 54 | 5.62e-02 | -1.50e-01 | 0.796000 |
| REACTOME INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING | 103 | 5.77e-02 | -1.08e-01 | 0.810000 |
| REACTOME VESICLE MEDIATED TRANSPORT | 642 | 5.82e-02 | 4.38e-02 | 0.810000 |
| REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 | 54 | 6.16e-02 | -1.47e-01 | 0.849000 |
| REACTOME INTERFERON SIGNALING | 193 | 6.23e-02 | 7.78e-02 | 0.852000 |
| REACTOME METABOLISM OF POLYAMINES | 56 | 6.49e-02 | -1.43e-01 | 0.858000 |
| REACTOME INFLUENZA INFECTION | 149 | 6.51e-02 | -8.75e-02 | 0.858000 |
| REACTOME MRNA EDITING C TO U CONVERSION | 8 | 6.55e-02 | -3.76e-01 | 0.858000 |
| REACTOME VLDL ASSEMBLY | 5 | 6.59e-02 | -4.75e-01 | 0.858000 |
| REACTOME KILLING MECHANISMS | 11 | 6.66e-02 | 3.19e-01 | 0.858000 |
| REACTOME INTERLEUKIN 6 FAMILY SIGNALING | 24 | 6.71e-02 | 2.16e-01 | 0.858000 |
| REACTOME TRANSCRIPTIONAL REGULATION BY E2F6 | 32 | 6.75e-02 | 1.87e-01 | 0.858000 |
| REACTOME DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING | 61 | 6.90e-02 | -1.35e-01 | 0.858000 |
| REACTOME PREGNENOLONE BIOSYNTHESIS | 12 | 6.97e-02 | 3.02e-01 | 0.858000 |
| REACTOME MAPK1 ERK2 ACTIVATION | 9 | 7.14e-02 | 3.47e-01 | 0.858000 |
| REACTOME RORA ACTIVATES GENE EXPRESSION | 17 | 7.19e-02 | 2.52e-01 | 0.858000 |
| REACTOME SCAVENGING BY CLASS B RECEPTORS | 6 | 7.21e-02 | -4.24e-01 | 0.858000 |
| REACTOME REGULATION OF RAS BY GAPS | 66 | 7.22e-02 | -1.28e-01 | 0.858000 |
| REACTOME NR1H2 AND NR1H3 MEDIATED SIGNALING | 46 | 7.34e-02 | 1.53e-01 | 0.858000 |
| REACTOME SURFACTANT METABOLISM | 28 | 7.36e-02 | -1.95e-01 | 0.858000 |
| REACTOME MAPK6 MAPK4 SIGNALING | 91 | 7.42e-02 | -1.08e-01 | 0.858000 |
| REACTOME FORMATION OF XYLULOSE 5 PHOSPHATE | 5 | 7.55e-02 | 4.59e-01 | 0.858000 |
| REACTOME ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS | 20 | 7.56e-02 | 2.29e-01 | 0.858000 |
| REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB | 5 | 7.59e-02 | -4.58e-01 | 0.858000 |
| REACTOME FCERI MEDIATED NF KB ACTIVATION | 78 | 7.60e-02 | -1.16e-01 | 0.858000 |
| REACTOME MITOTIC PROMETAPHASE | 194 | 7.61e-02 | 7.39e-02 | 0.858000 |
| REACTOME SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS | 43 | 7.71e-02 | -1.56e-01 | 0.858000 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH PI3K | 7 | 7.72e-02 | -3.86e-01 | 0.858000 |
| REACTOME PEPTIDE HORMONE METABOLISM | 84 | 7.74e-02 | -1.11e-01 | 0.858000 |
| REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX | 13 | 7.76e-02 | -2.83e-01 | 0.858000 |
| REACTOME CREATION OF C4 AND C2 ACTIVATORS | 14 | 7.91e-02 | -2.71e-01 | 0.858000 |
| REACTOME MUSCLE CONTRACTION | 197 | 7.93e-02 | -7.25e-02 | 0.858000 |
| REACTOME PEPTIDE HORMONE BIOSYNTHESIS | 13 | 7.94e-02 | -2.81e-01 | 0.858000 |
| REACTOME SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA | 52 | 7.97e-02 | -1.40e-01 | 0.858000 |
| REACTOME INTERLEUKIN 20 FAMILY SIGNALING | 25 | 8.04e-02 | 2.02e-01 | 0.858000 |
| REACTOME METHIONINE SALVAGE PATHWAY | 6 | 8.17e-02 | 4.10e-01 | 0.858000 |
| REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | 53 | 8.18e-02 | -1.38e-01 | 0.858000 |
| REACTOME TIE2 SIGNALING | 18 | 8.27e-02 | -2.36e-01 | 0.858000 |
| REACTOME TELOMERE EXTENSION BY TELOMERASE | 22 | 8.34e-02 | 2.13e-01 | 0.858000 |
| REACTOME ER TO GOLGI ANTEROGRADE TRANSPORT | 152 | 8.36e-02 | 8.13e-02 | 0.858000 |
| REACTOME MTORC1 MEDIATED SIGNALLING | 23 | 8.44e-02 | 2.08e-01 | 0.858000 |
| REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | 93 | 8.52e-02 | -1.03e-01 | 0.858000 |
| REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION | 250 | 8.52e-02 | -6.32e-02 | 0.858000 |
| REACTOME IRS ACTIVATION | 5 | 8.62e-02 | 4.43e-01 | 0.858000 |
| REACTOME RHOU GTPASE CYCLE | 37 | 8.65e-02 | 1.63e-01 | 0.858000 |
| REACTOME DEFECTIVE CSF2RB CAUSES SMDP5 | 7 | 8.76e-02 | -3.73e-01 | 0.858000 |
| REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | 30 | 8.78e-02 | -1.80e-01 | 0.858000 |
| REACTOME IKBA VARIANT LEADS TO EDA ID | 6 | 8.78e-02 | 4.02e-01 | 0.858000 |
| REACTOME EXTENSION OF TELOMERES | 49 | 8.87e-02 | 1.41e-01 | 0.858000 |
| REACTOME SIGNALING BY PDGFR IN DISEASE | 20 | 8.99e-02 | -2.19e-01 | 0.858000 |
| REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | 46 | 9.03e-02 | -1.44e-01 | 0.858000 |
| REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS | 6 | 9.04e-02 | 3.99e-01 | 0.858000 |
| REACTOME TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX | 14 | 9.05e-02 | 2.61e-01 | 0.858000 |
| REACTOME INTEGRIN CELL SURFACE INTERACTIONS | 83 | 9.11e-02 | -1.07e-01 | 0.858000 |
| REACTOME TRNA AMINOACYLATION | 40 | 9.17e-02 | 1.54e-01 | 0.858000 |
| REACTOME CIRCADIAN CLOCK | 68 | 9.20e-02 | 1.18e-01 | 0.858000 |
| REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | 86 | 9.25e-02 | -1.05e-01 | 0.858000 |
| REACTOME APOPTOSIS | 173 | 9.28e-02 | -7.41e-02 | 0.858000 |
| REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | 21 | 9.33e-02 | -2.12e-01 | 0.858000 |
| REACTOME TNFR2 NON CANONICAL NF KB PATHWAY | 96 | 9.39e-02 | -9.89e-02 | 0.858000 |
| REACTOME LGI ADAM INTERACTIONS | 14 | 9.42e-02 | -2.58e-01 | 0.858000 |
| REACTOME ECM PROTEOGLYCANS | 73 | 9.45e-02 | -1.13e-01 | 0.858000 |
| REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS | 14 | 9.48e-02 | -2.58e-01 | 0.858000 |
| REACTOME AMINO ACIDS REGULATE MTORC1 | 53 | 9.49e-02 | 1.33e-01 | 0.858000 |
| REACTOME PLATELET AGGREGATION PLUG FORMATION | 39 | 9.58e-02 | -1.54e-01 | 0.858000 |
| REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER | 49 | 9.59e-02 | 1.38e-01 | 0.858000 |
| REACTOME INITIAL TRIGGERING OF COMPLEMENT | 21 | 9.61e-02 | -2.10e-01 | 0.858000 |
| REACTOME ASPIRIN ADME | 42 | 9.62e-02 | -1.48e-01 | 0.858000 |
| REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN | 37 | 9.72e-02 | 1.58e-01 | 0.858000 |
| REACTOME SPERM MOTILITY AND TAXES | 9 | 9.74e-02 | -3.19e-01 | 0.858000 |
| REACTOME MET ACTIVATES PTPN11 | 5 | 9.76e-02 | -4.28e-01 | 0.858000 |
| REACTOME TRIGLYCERIDE METABOLISM | 35 | 9.79e-02 | -1.62e-01 | 0.858000 |
| REACTOME ACTIVATION OF AMPK DOWNSTREAM OF NMDARS | 28 | 9.92e-02 | 1.80e-01 | 0.858000 |
| REACTOME UCH PROTEINASES | 99 | 9.95e-02 | -9.58e-02 | 0.858000 |
| REACTOME MITOPHAGY | 28 | 1.00e-01 | -1.79e-01 | 0.858000 |
| REACTOME FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS | 8 | 1.01e-01 | -3.35e-01 | 0.858000 |
| REACTOME MET PROMOTES CELL MOTILITY | 41 | 1.01e-01 | -1.48e-01 | 0.858000 |
| REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE | 71 | 1.01e-01 | 1.13e-01 | 0.858000 |
| REACTOME REGULATION OF MECP2 EXPRESSION AND ACTIVITY | 30 | 1.02e-01 | 1.72e-01 | 0.861000 |
| REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | 11 | 1.03e-01 | -2.84e-01 | 0.861000 |
| REACTOME GROWTH HORMONE RECEPTOR SIGNALING | 24 | 1.03e-01 | 1.92e-01 | 0.861000 |
| REACTOME SIGNALLING TO RAS | 20 | 1.03e-01 | -2.10e-01 | 0.861000 |
| REACTOME OAS ANTIVIRAL RESPONSE | 8 | 1.05e-01 | 3.31e-01 | 0.865000 |
| REACTOME PINK1 PRKN MEDIATED MITOPHAGY | 22 | 1.05e-01 | -2.00e-01 | 0.865000 |
| REACTOME G ALPHA Q SIGNALLING EVENTS | 206 | 1.05e-01 | -6.55e-02 | 0.865000 |
| REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | 353 | 1.06e-01 | -5.01e-02 | 0.865000 |
| REACTOME REGULATION OF LIPID METABOLISM BY PPARALPHA | 115 | 1.06e-01 | 8.72e-02 | 0.865000 |
| REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | 14 | 1.07e-01 | 2.49e-01 | 0.868000 |
| REACTOME REGULATION OF TP53 ACTIVITY | 156 | 1.09e-01 | 7.43e-02 | 0.872000 |
| REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | 29 | 1.10e-01 | 1.71e-01 | 0.872000 |
| REACTOME LATE ENDOSOMAL MICROAUTOPHAGY | 33 | 1.11e-01 | 1.60e-01 | 0.872000 |
| REACTOME MITOCHONDRIAL TRANSLATION | 93 | 1.11e-01 | -9.56e-02 | 0.872000 |
| REACTOME GRB7 EVENTS IN ERBB2 SIGNALING | 5 | 1.11e-01 | -4.12e-01 | 0.872000 |
| REACTOME DOPAMINE RECEPTORS | 5 | 1.13e-01 | 4.09e-01 | 0.872000 |
| REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | 15 | 1.14e-01 | -2.35e-01 | 0.872000 |
| REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS | 6 | 1.15e-01 | -3.71e-01 | 0.872000 |
| REACTOME RAB REGULATION OF TRAFFICKING | 110 | 1.15e-01 | 8.69e-02 | 0.872000 |
| REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III | 31 | 1.16e-01 | 1.63e-01 | 0.872000 |
| REACTOME GPVI MEDIATED ACTIVATION CASCADE | 35 | 1.17e-01 | -1.53e-01 | 0.872000 |
| REACTOME SIGNALING BY MET | 78 | 1.18e-01 | -1.02e-01 | 0.872000 |
| REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION | 1356 | 1.18e-01 | 2.53e-02 | 0.872000 |
| REACTOME SIGNALING BY LEPTIN | 11 | 1.19e-01 | 2.72e-01 | 0.872000 |
| REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF | 53 | 1.19e-01 | 1.24e-01 | 0.872000 |
| REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS | 43 | 1.19e-01 | 1.37e-01 | 0.872000 |
| REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS | 81 | 1.19e-01 | 1.00e-01 | 0.872000 |
| REACTOME CELL CYCLE MITOTIC | 539 | 1.20e-01 | 3.91e-02 | 0.872000 |
| REACTOME TRANSCRIPTIONAL REGULATION BY RUNX3 | 94 | 1.21e-01 | -9.26e-02 | 0.872000 |
| REACTOME SYNTHESIS OF PIPS AT THE ER MEMBRANE | 5 | 1.22e-01 | 4.00e-01 | 0.872000 |
| REACTOME REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION | 9 | 1.22e-01 | 2.98e-01 | 0.872000 |
| REACTOME DNA REPLICATION PRE INITIATION | 150 | 1.22e-01 | -7.32e-02 | 0.872000 |
| REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS | 55 | 1.22e-01 | -1.21e-01 | 0.872000 |
| REACTOME CYTOSOLIC TRNA AMINOACYLATION | 22 | 1.22e-01 | 1.90e-01 | 0.872000 |
| REACTOME FC EPSILON RECEPTOR FCERI SIGNALING | 127 | 1.22e-01 | -7.94e-02 | 0.872000 |
| REACTOME RHOT1 GTPASE CYCLE | 5 | 1.23e-01 | 3.99e-01 | 0.872000 |
| REACTOME SIGNALING BY THE B CELL RECEPTOR BCR | 106 | 1.24e-01 | -8.65e-02 | 0.872000 |
| REACTOME INTERLEUKIN 9 SIGNALING | 7 | 1.25e-01 | 3.35e-01 | 0.872000 |
| REACTOME MEIOTIC RECOMBINATION | 80 | 1.26e-01 | -9.89e-02 | 0.872000 |
| REACTOME SODIUM PROTON EXCHANGERS | 7 | 1.26e-01 | 3.34e-01 | 0.872000 |
| REACTOME DISORDERS OF TRANSMEMBRANE TRANSPORTERS | 170 | 1.27e-01 | -6.79e-02 | 0.872000 |
| REACTOME REGULATION BY C FLIP | 11 | 1.28e-01 | -2.65e-01 | 0.872000 |
| REACTOME COLLAGEN DEGRADATION | 61 | 1.29e-01 | -1.13e-01 | 0.872000 |
| REACTOME MIRO GTPASE CYCLE | 8 | 1.29e-01 | 3.10e-01 | 0.872000 |
| REACTOME MULTIFUNCTIONAL ANION EXCHANGERS | 9 | 1.29e-01 | -2.92e-01 | 0.872000 |
| REACTOME GAB1 SIGNALOSOME | 17 | 1.31e-01 | -2.12e-01 | 0.872000 |
| REACTOME RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION | 6 | 1.32e-01 | 3.55e-01 | 0.872000 |
| REACTOME DEGRADATION OF DVL | 56 | 1.33e-01 | -1.16e-01 | 0.872000 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING | 5 | 1.33e-01 | 3.88e-01 | 0.872000 |
| REACTOME CRMPS IN SEMA3A SIGNALING | 15 | 1.33e-01 | -2.24e-01 | 0.872000 |
| REACTOME ALPHA DEFENSINS | 6 | 1.33e-01 | 3.54e-01 | 0.872000 |
| REACTOME PARASITE INFECTION | 57 | 1.34e-01 | -1.15e-01 | 0.872000 |
| REACTOME SEROTONIN NEUROTRANSMITTER RELEASE CYCLE | 17 | 1.34e-01 | -2.10e-01 | 0.872000 |
| REACTOME TELOMERE C STRAND SYNTHESIS INITIATION | 12 | 1.34e-01 | 2.50e-01 | 0.872000 |
| REACTOME PROTEIN UBIQUITINATION | 76 | 1.35e-01 | -9.92e-02 | 0.872000 |
| REACTOME MAPK3 ERK1 ACTIVATION | 10 | 1.35e-01 | 2.73e-01 | 0.872000 |
| REACTOME TRYPTOPHAN CATABOLISM | 14 | 1.35e-01 | 2.31e-01 | 0.872000 |
| REACTOME SIGNALING BY NTRK2 TRKB | 25 | 1.35e-01 | -1.72e-01 | 0.872000 |
| REACTOME PLASMA LIPOPROTEIN CLEARANCE | 37 | 1.36e-01 | -1.42e-01 | 0.872000 |
| REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | 99 | 1.36e-01 | -8.67e-02 | 0.872000 |
| REACTOME TRNA PROCESSING | 105 | 1.36e-01 | 8.41e-02 | 0.872000 |
| REACTOME FRUCTOSE METABOLISM | 7 | 1.37e-01 | 3.25e-01 | 0.872000 |
| REACTOME REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS | 14 | 1.37e-01 | 2.29e-01 | 0.872000 |
| REACTOME LYSOSPHINGOLIPID AND LPA RECEPTORS | 14 | 1.38e-01 | -2.29e-01 | 0.872000 |
| REACTOME GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | 34 | 1.38e-01 | 1.47e-01 | 0.872000 |
| REACTOME MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS | 17 | 1.40e-01 | 2.07e-01 | 0.872000 |
| REACTOME PURINE CATABOLISM | 17 | 1.41e-01 | -2.06e-01 | 0.872000 |
| REACTOME NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 11 | 1.41e-01 | -2.56e-01 | 0.872000 |
| REACTOME BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA | 6 | 1.41e-01 | 3.47e-01 | 0.872000 |
| REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | 20 | 1.42e-01 | 1.90e-01 | 0.872000 |
| REACTOME SIGNALING BY NOTCH4 | 80 | 1.42e-01 | -9.49e-02 | 0.872000 |
| REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP | 41 | 1.42e-01 | 1.32e-01 | 0.872000 |
| REACTOME CELLULAR SENESCENCE | 189 | 1.43e-01 | 6.18e-02 | 0.872000 |
| REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX | 21 | 1.43e-01 | -1.84e-01 | 0.872000 |
| REACTOME ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM | 12 | 1.44e-01 | 2.44e-01 | 0.872000 |
| REACTOME DEGRADATION OF AXIN | 54 | 1.44e-01 | -1.15e-01 | 0.872000 |
| REACTOME M PHASE | 398 | 1.44e-01 | 4.27e-02 | 0.872000 |
| REACTOME NFE2L2 REGULATING ANTI OXIDANT DETOXIFICATION ENZYMES | 17 | 1.44e-01 | 2.04e-01 | 0.872000 |
| REACTOME METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS | 122 | 1.45e-01 | 7.64e-02 | 0.872000 |
| REACTOME ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION | 16 | 1.45e-01 | -2.10e-01 | 0.872000 |
| REACTOME SIGNALING BY GPCR | 673 | 1.46e-01 | -3.29e-02 | 0.873000 |
| REACTOME INTERLEUKIN 6 SIGNALING | 11 | 1.46e-01 | 2.53e-01 | 0.873000 |
| REACTOME NUCLEOTIDE CATABOLISM | 35 | 1.47e-01 | -1.42e-01 | 0.875000 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS | 9 | 1.49e-01 | 2.78e-01 | 0.883000 |
| REACTOME PYRIMIDINE SALVAGE | 10 | 1.50e-01 | -2.63e-01 | 0.886000 |
| REACTOME FLT3 SIGNALING BY CBL MUTANTS | 7 | 1.51e-01 | -3.14e-01 | 0.887000 |
| REACTOME INTERLEUKIN 36 PATHWAY | 7 | 1.53e-01 | -3.12e-01 | 0.899000 |
| REACTOME SIGNALING BY BMP | 27 | 1.55e-01 | 1.58e-01 | 0.900000 |
| REACTOME L1CAM INTERACTIONS | 112 | 1.55e-01 | -7.78e-02 | 0.900000 |
| REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION | 8 | 1.55e-01 | -2.90e-01 | 0.900000 |
| REACTOME N GLYCAN ANTENNAE ELONGATION | 15 | 1.57e-01 | -2.11e-01 | 0.907000 |
| REACTOME SUMOYLATION OF DNA METHYLATION PROTEINS | 16 | 1.60e-01 | 2.03e-01 | 0.913000 |
| REACTOME TP53 REGULATES METABOLIC GENES | 81 | 1.60e-01 | 9.02e-02 | 0.913000 |
| REACTOME TACHYKININ RECEPTORS BIND TACHYKININS | 5 | 1.61e-01 | 3.62e-01 | 0.913000 |
| REACTOME REDUCTION OF CYTOSOLIC CA LEVELS | 11 | 1.61e-01 | 2.44e-01 | 0.913000 |
| REACTOME GOLGI TO ER RETROGRADE TRANSPORT | 132 | 1.61e-01 | 7.06e-02 | 0.913000 |
| REACTOME PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS | 7 | 1.61e-01 | -3.06e-01 | 0.913000 |
| REACTOME BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA | 5 | 1.62e-01 | 3.61e-01 | 0.913000 |
| REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER | 77 | 1.63e-01 | -9.19e-02 | 0.916000 |
| REACTOME SENSORY PERCEPTION OF SALTY TASTE | 6 | 1.63e-01 | 3.28e-01 | 0.916000 |
| REACTOME MET ACTIVATES RAS SIGNALING | 11 | 1.66e-01 | -2.41e-01 | 0.920000 |
| REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL | 41 | 1.68e-01 | 1.25e-01 | 0.920000 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES | 49 | 1.68e-01 | 1.14e-01 | 0.920000 |
| REACTOME E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS | 58 | 1.68e-01 | -1.05e-01 | 0.920000 |
| REACTOME P2Y RECEPTORS | 9 | 1.69e-01 | -2.65e-01 | 0.920000 |
| REACTOME NETRIN 1 SIGNALING | 49 | 1.70e-01 | -1.13e-01 | 0.920000 |
| REACTOME SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL | 8 | 1.70e-01 | 2.80e-01 | 0.920000 |
| REACTOME BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA | 17 | 1.71e-01 | 1.92e-01 | 0.920000 |
| REACTOME DNA DOUBLE STRAND BREAK REPAIR | 162 | 1.72e-01 | 6.21e-02 | 0.920000 |
| REACTOME IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN | 5 | 1.72e-01 | 3.52e-01 | 0.920000 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN | 21 | 1.73e-01 | 1.72e-01 | 0.920000 |
| REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE | 8 | 1.74e-01 | 2.78e-01 | 0.920000 |
| REACTOME CARNITINE METABOLISM | 13 | 1.75e-01 | 2.17e-01 | 0.920000 |
| REACTOME MET RECEPTOR RECYCLING | 10 | 1.75e-01 | -2.48e-01 | 0.920000 |
| REACTOME GLUCURONIDATION | 23 | 1.75e-01 | -1.63e-01 | 0.920000 |
| REACTOME CREB3 FACTORS ACTIVATE GENES | 8 | 1.76e-01 | -2.76e-01 | 0.920000 |
| REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS | 83 | 1.76e-01 | -8.59e-02 | 0.920000 |
| REACTOME DARPP 32 EVENTS | 24 | 1.76e-01 | -1.59e-01 | 0.920000 |
| REACTOME EGFR TRANSACTIVATION BY GASTRIN | 9 | 1.77e-01 | -2.60e-01 | 0.920000 |
| REACTOME DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE | 17 | 1.77e-01 | -1.89e-01 | 0.920000 |
| REACTOME GLUCAGON TYPE LIGAND RECEPTORS | 32 | 1.77e-01 | -1.38e-01 | 0.920000 |
| REACTOME SARS COV 2 ACTIVATES MODULATES INNATE AND ADAPTIVE IMMUNE RESPONSES | 118 | 1.78e-01 | 7.18e-02 | 0.920000 |
| REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | 24 | 1.79e-01 | 1.59e-01 | 0.920000 |
| REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | 36 | 1.80e-01 | 1.29e-01 | 0.920000 |
| REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE GIP | 12 | 1.80e-01 | -2.23e-01 | 0.920000 |
| REACTOME TCR SIGNALING | 113 | 1.82e-01 | -7.26e-02 | 0.920000 |
| REACTOME HEDGEHOG ON STATE | 85 | 1.83e-01 | -8.36e-02 | 0.920000 |
| REACTOME HDL REMODELING | 10 | 1.84e-01 | -2.43e-01 | 0.920000 |
| REACTOME LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX | 5 | 1.84e-01 | 3.43e-01 | 0.920000 |
| REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER | 18 | 1.84e-01 | -1.81e-01 | 0.920000 |
| REACTOME SIGNALING BY INTERLEUKINS | 444 | 1.84e-01 | -3.68e-02 | 0.920000 |
| REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX | 36 | 1.84e-01 | 1.28e-01 | 0.920000 |
| REACTOME SPRY REGULATION OF FGF SIGNALING | 16 | 1.85e-01 | -1.92e-01 | 0.920000 |
| REACTOME RHOV GTPASE CYCLE | 36 | 1.85e-01 | 1.28e-01 | 0.920000 |
| REACTOME DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX | 83 | 1.85e-01 | -8.42e-02 | 0.920000 |
| REACTOME HOST INTERACTIONS OF HIV FACTORS | 127 | 1.85e-01 | -6.81e-02 | 0.920000 |
| REACTOME THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT | 77 | 1.85e-01 | -8.73e-02 | 0.920000 |
| REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | 21 | 1.86e-01 | 1.67e-01 | 0.920000 |
| REACTOME RHO GTPASES ACTIVATE WASPS AND WAVES | 34 | 1.86e-01 | -1.31e-01 | 0.920000 |
| REACTOME RND3 GTPASE CYCLE | 41 | 1.87e-01 | 1.19e-01 | 0.921000 |
| REACTOME MRNA EDITING | 10 | 1.88e-01 | -2.40e-01 | 0.921000 |
| REACTOME MUSCARINIC ACETYLCHOLINE RECEPTORS | 5 | 1.90e-01 | -3.39e-01 | 0.921000 |
| REACTOME ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY | 10 | 1.91e-01 | -2.39e-01 | 0.921000 |
| REACTOME RUNX2 REGULATES BONE DEVELOPMENT | 29 | 1.92e-01 | 1.40e-01 | 0.921000 |
| REACTOME OTHER SEMAPHORIN INTERACTIONS | 18 | 1.92e-01 | -1.78e-01 | 0.921000 |
| REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | 36 | 1.92e-01 | 1.26e-01 | 0.921000 |
| REACTOME CREATINE METABOLISM | 9 | 1.95e-01 | -2.50e-01 | 0.921000 |
| REACTOME PTEN REGULATION | 135 | 1.95e-01 | 6.46e-02 | 0.921000 |
| REACTOME LDL CLEARANCE | 19 | 1.95e-01 | -1.72e-01 | 0.921000 |
| REACTOME GLUCONEOGENESIS | 33 | 1.95e-01 | -1.30e-01 | 0.921000 |
| REACTOME NUCLEOTIDE SALVAGE | 21 | 1.97e-01 | -1.62e-01 | 0.921000 |
| REACTOME AURKA ACTIVATION BY TPX2 | 69 | 1.98e-01 | 8.95e-02 | 0.921000 |
| REACTOME LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME | 11 | 1.99e-01 | 2.24e-01 | 0.921000 |
| REACTOME CD28 DEPENDENT PI3K AKT SIGNALING | 22 | 1.99e-01 | 1.58e-01 | 0.921000 |
| REACTOME SIGNALING BY NODAL | 20 | 2.00e-01 | 1.66e-01 | 0.921000 |
| REACTOME PHASE 0 RAPID DEPOLARISATION | 31 | 2.00e-01 | -1.33e-01 | 0.921000 |
| REACTOME CELLULAR RESPONSE TO HYPOXIA | 74 | 2.00e-01 | -8.61e-02 | 0.921000 |
| REACTOME CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE | 49 | 2.01e-01 | 1.06e-01 | 0.921000 |
| REACTOME DEFECTIVE EXT2 CAUSES EXOSTOSES 2 | 12 | 2.01e-01 | -2.13e-01 | 0.921000 |
| REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI | 26 | 2.02e-01 | -1.45e-01 | 0.921000 |
| REACTOME RHO GTPASE CYCLE | 423 | 2.02e-01 | 3.62e-02 | 0.921000 |
| REACTOME PROCESSING OF DNA DOUBLE STRAND BREAK ENDS | 93 | 2.02e-01 | 7.65e-02 | 0.921000 |
| REACTOME ACYL CHAIN REMODELLING OF PI | 17 | 2.03e-01 | -1.78e-01 | 0.921000 |
| REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY | 72 | 2.03e-01 | -8.67e-02 | 0.921000 |
| REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES | 27 | 2.04e-01 | -1.41e-01 | 0.921000 |
| REACTOME REGULATION OF SIGNALING BY CBL | 22 | 2.04e-01 | -1.56e-01 | 0.921000 |
| REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | 73 | 2.07e-01 | -8.55e-02 | 0.921000 |
| REACTOME LIPOPHAGY | 9 | 2.08e-01 | 2.43e-01 | 0.921000 |
| REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | 11 | 2.08e-01 | -2.19e-01 | 0.921000 |
| REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS | 20 | 2.10e-01 | 1.62e-01 | 0.921000 |
| REACTOME SCAVENGING OF HEME FROM PLASMA | 13 | 2.10e-01 | -2.01e-01 | 0.921000 |
| REACTOME G ALPHA S SIGNALLING EVENTS | 155 | 2.11e-01 | -5.82e-02 | 0.921000 |
| REACTOME SELENOAMINO ACID METABOLISM | 108 | 2.11e-01 | -6.97e-02 | 0.921000 |
| REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | 31 | 2.11e-01 | 1.30e-01 | 0.921000 |
| REACTOME SIGNALING BY FLT3 ITD AND TKD MUTANTS | 16 | 2.11e-01 | -1.80e-01 | 0.921000 |
| REACTOME AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS | 9 | 2.11e-01 | 2.41e-01 | 0.921000 |
| REACTOME RND1 GTPASE CYCLE | 41 | 2.12e-01 | 1.13e-01 | 0.921000 |
| REACTOME NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10 | 12 | 2.12e-01 | 2.08e-01 | 0.921000 |
| REACTOME SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER | 54 | 2.12e-01 | 9.82e-02 | 0.921000 |
| REACTOME PI3K EVENTS IN ERBB2 SIGNALING | 16 | 2.12e-01 | -1.80e-01 | 0.921000 |
| REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS | 13 | 2.13e-01 | -2.00e-01 | 0.921000 |
| REACTOME FCGR ACTIVATION | 11 | 2.14e-01 | -2.16e-01 | 0.921000 |
| REACTOME SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX | 15 | 2.14e-01 | 1.85e-01 | 0.921000 |
| REACTOME SIGNALING BY EGFR IN CANCER | 25 | 2.15e-01 | -1.43e-01 | 0.921000 |
| REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | 14 | 2.15e-01 | -1.91e-01 | 0.921000 |
| REACTOME DNA REPLICATION | 178 | 2.15e-01 | -5.39e-02 | 0.921000 |
| REACTOME GLUCOCORTICOID BIOSYNTHESIS | 10 | 2.16e-01 | -2.26e-01 | 0.921000 |
| REACTOME PI5P REGULATES TP53 ACETYLATION | 9 | 2.16e-01 | 2.38e-01 | 0.921000 |
| REACTOME ALK MUTANTS BIND TKIS | 12 | 2.16e-01 | -2.06e-01 | 0.921000 |
| REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS | 63 | 2.17e-01 | -9.00e-02 | 0.921000 |
| REACTOME TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS | 52 | 2.17e-01 | 9.90e-02 | 0.921000 |
| REACTOME SIGNALING BY CSF3 G CSF | 30 | 2.18e-01 | -1.30e-01 | 0.921000 |
| REACTOME INTERLEUKIN 1 FAMILY SIGNALING | 146 | 2.19e-01 | -5.90e-02 | 0.921000 |
| REACTOME SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS | 16 | 2.19e-01 | -1.78e-01 | 0.921000 |
| REACTOME SMAC XIAP REGULATED APOPTOTIC RESPONSE | 7 | 2.19e-01 | -2.68e-01 | 0.921000 |
| REACTOME TRIGLYCERIDE CATABOLISM | 23 | 2.19e-01 | -1.48e-01 | 0.921000 |
| REACTOME REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO | 10 | 2.20e-01 | -2.24e-01 | 0.921000 |
| REACTOME SENSORY PERCEPTION | 555 | 2.21e-01 | -3.04e-02 | 0.921000 |
| REACTOME HOMOLOGY DIRECTED REPAIR | 132 | 2.21e-01 | 6.17e-02 | 0.921000 |
| REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION | 90 | 2.21e-01 | 7.46e-02 | 0.921000 |
| REACTOME FATTY ACIDS BOUND TO GPR40 FFAR1 REGULATE INSULIN SECRETION | 8 | 2.22e-01 | 2.49e-01 | 0.921000 |
| REACTOME RND2 GTPASE CYCLE | 42 | 2.23e-01 | 1.09e-01 | 0.921000 |
| REACTOME GLYCOGEN STORAGE DISEASES | 15 | 2.23e-01 | -1.82e-01 | 0.921000 |
| REACTOME INTEGRIN SIGNALING | 27 | 2.23e-01 | -1.35e-01 | 0.921000 |
| REACTOME APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS | 87 | 2.23e-01 | -7.56e-02 | 0.921000 |
| REACTOME FORMATION OF THE CORNIFIED ENVELOPE | 125 | 2.24e-01 | -6.30e-02 | 0.921000 |
| REACTOME RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION | 22 | 2.26e-01 | 1.49e-01 | 0.921000 |
| REACTOME UREA CYCLE | 9 | 2.27e-01 | -2.33e-01 | 0.921000 |
| REACTOME DNA METHYLATION | 58 | 2.27e-01 | -9.17e-02 | 0.921000 |
| REACTOME PHASE 2 PLATEAU PHASE | 14 | 2.28e-01 | -1.86e-01 | 0.921000 |
| REACTOME OVARIAN TUMOR DOMAIN PROTEASES | 36 | 2.28e-01 | 1.16e-01 | 0.921000 |
| REACTOME POTASSIUM CHANNELS | 102 | 2.30e-01 | -6.88e-02 | 0.921000 |
| REACTOME SIGNALING BY NOTCH2 | 32 | 2.30e-01 | -1.22e-01 | 0.921000 |
| REACTOME REGULATION OF IFNA IFNB SIGNALING | 23 | 2.32e-01 | 1.44e-01 | 0.921000 |
| REACTOME TRIF MEDIATED PROGRAMMED CELL DEATH | 9 | 2.32e-01 | 2.30e-01 | 0.921000 |
| REACTOME SIGNALING BY ACTIVIN | 15 | 2.32e-01 | 1.78e-01 | 0.921000 |
| REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM | 45 | 2.34e-01 | -1.03e-01 | 0.921000 |
| REACTOME SIGNAL ATTENUATION | 10 | 2.34e-01 | 2.18e-01 | 0.921000 |
| REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | 134 | 2.34e-01 | -5.96e-02 | 0.921000 |
| REACTOME FRUCTOSE CATABOLISM | 5 | 2.34e-01 | 3.07e-01 | 0.921000 |
| REACTOME DEFECTIVE B4GALT1 CAUSES B4GALT1 CDG CDG 2D | 8 | 2.34e-01 | -2.43e-01 | 0.921000 |
| REACTOME DISEASES OF DNA REPAIR | 51 | 2.34e-01 | 9.63e-02 | 0.921000 |
| REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | 23 | 2.35e-01 | -1.43e-01 | 0.921000 |
| REACTOME SIGNALING BY SCF KIT | 42 | 2.35e-01 | -1.06e-01 | 0.921000 |
| REACTOME ATTACHMENT AND ENTRY | 16 | 2.36e-01 | -1.71e-01 | 0.921000 |
| REACTOME G0 AND EARLY G1 | 27 | 2.36e-01 | 1.32e-01 | 0.921000 |
| REACTOME ASSEMBLY OF THE HIV VIRION | 16 | 2.36e-01 | 1.71e-01 | 0.921000 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES | 61 | 2.36e-01 | 8.77e-02 | 0.921000 |
| REACTOME MAPK FAMILY SIGNALING CASCADES | 314 | 2.38e-01 | -3.88e-02 | 0.922000 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH CDK5 | 6 | 2.38e-01 | -2.78e-01 | 0.922000 |
| REACTOME DISEASES ASSOCIATED WITH SURFACTANT METABOLISM | 9 | 2.38e-01 | -2.27e-01 | 0.922000 |
| REACTOME NEUROFASCIN INTERACTIONS | 6 | 2.40e-01 | -2.77e-01 | 0.925000 |
| REACTOME DNA DAMAGE RECOGNITION IN GG NER | 36 | 2.40e-01 | 1.13e-01 | 0.925000 |
| REACTOME EPITHELIAL MESENCHYMAL TRANSITION EMT DURING GASTRULATION | 7 | 2.41e-01 | -2.56e-01 | 0.925000 |
| REACTOME MRNA SPLICING | 197 | 2.42e-01 | 4.83e-02 | 0.929000 |
| REACTOME ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS | 20 | 2.43e-01 | 1.51e-01 | 0.929000 |
| REACTOME IRF3 MEDIATED INDUCTION OF TYPE I IFN | 13 | 2.44e-01 | 1.87e-01 | 0.931000 |
| REACTOME IRAK4 DEFICIENCY TLR2 4 | 17 | 2.44e-01 | -1.63e-01 | 0.931000 |
| REACTOME RHO GTPASES ACTIVATE KTN1 | 11 | 2.45e-01 | -2.02e-01 | 0.932000 |
| REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | 122 | 2.46e-01 | -6.08e-02 | 0.935000 |
| REACTOME FORMATION OF TC NER PRE INCISION COMPLEX | 51 | 2.51e-01 | 9.29e-02 | 0.940000 |
| REACTOME SCAVENGING BY CLASS F RECEPTORS | 6 | 2.51e-01 | -2.71e-01 | 0.940000 |
| REACTOME SIGNALING BY ERBB4 | 57 | 2.52e-01 | -8.78e-02 | 0.940000 |
| REACTOME ACTIVATION OF RAC1 | 12 | 2.52e-01 | 1.91e-01 | 0.940000 |
| REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX | 32 | 2.53e-01 | 1.17e-01 | 0.940000 |
| REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS | 19 | 2.53e-01 | -1.51e-01 | 0.940000 |
| REACTOME MET RECEPTOR ACTIVATION | 6 | 2.53e-01 | -2.69e-01 | 0.940000 |
| REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | 55 | 2.55e-01 | 8.87e-02 | 0.940000 |
| REACTOME PROGRAMMED CELL DEATH | 204 | 2.55e-01 | -4.62e-02 | 0.940000 |
| REACTOME SENSORY PROCESSING OF SOUND | 72 | 2.57e-01 | -7.73e-02 | 0.940000 |
| REACTOME INTERLEUKIN 2 SIGNALING | 11 | 2.59e-01 | 1.97e-01 | 0.940000 |
| REACTOME SIGNALING BY FGFR4 | 40 | 2.59e-01 | -1.03e-01 | 0.940000 |
| REACTOME STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS | 10 | 2.59e-01 | -2.06e-01 | 0.940000 |
| REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY | 46 | 2.60e-01 | -9.59e-02 | 0.940000 |
| REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING | 30 | 2.61e-01 | -1.19e-01 | 0.940000 |
| REACTOME TRIGLYCERIDE BIOSYNTHESIS | 12 | 2.61e-01 | -1.87e-01 | 0.940000 |
| REACTOME SYNTHESIS OF LIPOXINS LX | 6 | 2.61e-01 | -2.65e-01 | 0.940000 |
| REACTOME NETRIN MEDIATED REPULSION SIGNALS | 8 | 2.63e-01 | -2.29e-01 | 0.940000 |
| REACTOME CREB PHOSPHORYLATION | 6 | 2.63e-01 | 2.64e-01 | 0.940000 |
| REACTOME METABOLISM OF FAT SOLUBLE VITAMINS | 46 | 2.63e-01 | -9.53e-02 | 0.940000 |
| REACTOME SIGNALING BY TGFB FAMILY MEMBERS | 119 | 2.64e-01 | 5.93e-02 | 0.940000 |
| REACTOME RHO GTPASES ACTIVATE NADPH OXIDASES | 21 | 2.64e-01 | -1.41e-01 | 0.940000 |
| REACTOME CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY | 84 | 2.65e-01 | -7.04e-02 | 0.940000 |
| REACTOME ACTIVATION OF MATRIX METALLOPROTEINASES | 30 | 2.66e-01 | -1.17e-01 | 0.940000 |
| REACTOME REGULATION OF KIT SIGNALING | 16 | 2.66e-01 | -1.61e-01 | 0.940000 |
| REACTOME FLT3 SIGNALING IN DISEASE | 28 | 2.66e-01 | -1.21e-01 | 0.940000 |
| REACTOME COPI MEDIATED ANTEROGRADE TRANSPORT | 101 | 2.67e-01 | 6.39e-02 | 0.940000 |
| REACTOME DISEASES OF GLYCOSYLATION | 137 | 2.67e-01 | -5.49e-02 | 0.940000 |
| REACTOME FLT3 SIGNALING THROUGH SRC FAMILY KINASES | 6 | 2.69e-01 | -2.61e-01 | 0.940000 |
| REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION | 11 | 2.69e-01 | -1.93e-01 | 0.940000 |
| REACTOME POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE | 25 | 2.69e-01 | 1.28e-01 | 0.940000 |
| REACTOME MITOCHONDRIAL BIOGENESIS | 87 | 2.71e-01 | 6.83e-02 | 0.940000 |
| REACTOME SYNDECAN INTERACTIONS | 26 | 2.71e-01 | -1.25e-01 | 0.940000 |
| REACTOME RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA | 7 | 2.72e-01 | -2.40e-01 | 0.940000 |
| REACTOME SARS COV 1 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS | 16 | 2.72e-01 | 1.59e-01 | 0.940000 |
| REACTOME MEIOSIS | 110 | 2.73e-01 | -6.05e-02 | 0.940000 |
| REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS | 16 | 2.73e-01 | -1.58e-01 | 0.940000 |
| REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR | 79 | 2.74e-01 | -7.12e-02 | 0.940000 |
| REACTOME INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION | 21 | 2.74e-01 | 1.38e-01 | 0.940000 |
| REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE | 11 | 2.75e-01 | 1.90e-01 | 0.940000 |
| REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | 80 | 2.75e-01 | 7.06e-02 | 0.940000 |
| REACTOME DISEASES OF MISMATCH REPAIR MMR | 5 | 2.75e-01 | 2.82e-01 | 0.940000 |
| REACTOME SYNTHESIS OF GDP MANNOSE | 5 | 2.75e-01 | 2.82e-01 | 0.940000 |
| REACTOME REGULATION OF PTEN STABILITY AND ACTIVITY | 67 | 2.75e-01 | -7.70e-02 | 0.940000 |
| REACTOME HORMONE LIGAND BINDING RECEPTORS | 12 | 2.76e-01 | -1.82e-01 | 0.940000 |
| REACTOME BIOSYNTHESIS OF MARESINS | 8 | 2.76e-01 | -2.22e-01 | 0.940000 |
| REACTOME ORGANIC CATION TRANSPORT | 10 | 2.77e-01 | 1.98e-01 | 0.940000 |
| REACTOME NUCLEAR EVENTS MEDIATED BY NFE2L2 | 77 | 2.78e-01 | -7.16e-02 | 0.940000 |
| REACTOME COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC | 98 | 2.78e-01 | 6.35e-02 | 0.940000 |
| REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K | 12 | 2.78e-01 | 1.81e-01 | 0.940000 |
| REACTOME SARS COV 2 TARGETS PDZ PROTEINS IN CELL CELL JUNCTION | 5 | 2.78e-01 | 2.80e-01 | 0.940000 |
| REACTOME TIGHT JUNCTION INTERACTIONS | 29 | 2.79e-01 | -1.16e-01 | 0.940000 |
| REACTOME HUR ELAVL1 BINDS AND STABILIZES MRNA | 8 | 2.80e-01 | -2.21e-01 | 0.940000 |
| REACTOME DISEASES OF METABOLISM | 237 | 2.81e-01 | -4.06e-02 | 0.940000 |
| REACTOME TELOMERE C STRAND LAGGING STRAND SYNTHESIS | 33 | 2.81e-01 | 1.08e-01 | 0.940000 |
| REACTOME DISEASES OF BASE EXCISION REPAIR | 5 | 2.82e-01 | 2.78e-01 | 0.940000 |
| REACTOME TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA | 17 | 2.83e-01 | 1.50e-01 | 0.940000 |
| REACTOME CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS | 19 | 2.84e-01 | -1.42e-01 | 0.940000 |
| REACTOME P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1 | 6 | 2.86e-01 | 2.52e-01 | 0.940000 |
| REACTOME FGFR2 ALTERNATIVE SPLICING | 27 | 2.88e-01 | -1.18e-01 | 0.940000 |
| REACTOME 2 LTR CIRCLE FORMATION | 7 | 2.88e-01 | -2.32e-01 | 0.940000 |
| REACTOME PI METABOLISM | 79 | 2.89e-01 | 6.89e-02 | 0.940000 |
| REACTOME NEGATIVE REGULATION OF FLT3 | 15 | 2.90e-01 | -1.58e-01 | 0.940000 |
| REACTOME UPTAKE AND FUNCTION OF ANTHRAX TOXINS | 11 | 2.91e-01 | 1.84e-01 | 0.940000 |
| REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION | 62 | 2.91e-01 | -7.76e-02 | 0.940000 |
| REACTOME SIGNALING BY HIPPO | 19 | 2.92e-01 | 1.40e-01 | 0.940000 |
| REACTOME VXPX CARGO TARGETING TO CILIUM | 20 | 2.92e-01 | 1.36e-01 | 0.940000 |
| REACTOME GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION | 14 | 2.93e-01 | -1.62e-01 | 0.940000 |
| REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | 66 | 2.93e-01 | -7.48e-02 | 0.940000 |
| REACTOME VITAMIN B2 RIBOFLAVIN METABOLISM | 7 | 2.94e-01 | 2.29e-01 | 0.940000 |
| REACTOME ERYTHROPOIETIN ACTIVATES RAS | 14 | 2.95e-01 | 1.62e-01 | 0.940000 |
| REACTOME CYTOPROTECTION BY HMOX1 | 59 | 2.96e-01 | 7.87e-02 | 0.940000 |
| REACTOME NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 11 | 2.97e-01 | -1.81e-01 | 0.940000 |
| REACTOME SIGNALING BY FGFR | 85 | 2.99e-01 | -6.52e-02 | 0.940000 |
| REACTOME PROLONGED ERK ACTIVATION EVENTS | 14 | 2.99e-01 | 1.60e-01 | 0.940000 |
| REACTOME DISEASES OF MITOTIC CELL CYCLE | 37 | 2.99e-01 | 9.87e-02 | 0.940000 |
| REACTOME COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC | 52 | 3.00e-01 | 8.31e-02 | 0.940000 |
| REACTOME INTERLEUKIN 2 FAMILY SIGNALING | 40 | 3.00e-01 | 9.47e-02 | 0.940000 |
| REACTOME CLEC7A DECTIN 1 SIGNALING | 97 | 3.00e-01 | -6.09e-02 | 0.940000 |
| REACTOME RIBAVIRIN ADME | 11 | 3.00e-01 | -1.80e-01 | 0.940000 |
| REACTOME RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY | 14 | 3.02e-01 | 1.59e-01 | 0.940000 |
| REACTOME SYNTHESIS OF PC | 27 | 3.02e-01 | -1.15e-01 | 0.940000 |
| REACTOME SYNTHESIS OF PI | 5 | 3.02e-01 | -2.66e-01 | 0.940000 |
| REACTOME COBALAMIN CBL METABOLISM | 7 | 3.02e-01 | 2.25e-01 | 0.940000 |
| REACTOME SUMOYLATION OF DNA REPLICATION PROTEINS | 46 | 3.03e-01 | 8.78e-02 | 0.940000 |
| REACTOME SIGNALING BY WNT IN CANCER | 32 | 3.03e-01 | 1.05e-01 | 0.940000 |
| REACTOME FCERI MEDIATED CA 2 MOBILIZATION | 30 | 3.04e-01 | -1.08e-01 | 0.940000 |
| REACTOME APEX1 INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | 7 | 3.05e-01 | 2.24e-01 | 0.940000 |
| REACTOME SIGNALING BY FGFR2 | 72 | 3.05e-01 | -6.99e-02 | 0.940000 |
| REACTOME INTERLEUKIN 1 SIGNALING | 110 | 3.05e-01 | -5.66e-02 | 0.940000 |
| REACTOME ADAPTIVE IMMUNE SYSTEM | 729 | 3.07e-01 | -2.22e-02 | 0.940000 |
| REACTOME FGFR1C LIGAND BINDING AND ACTIVATION | 11 | 3.07e-01 | -1.78e-01 | 0.940000 |
| REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | 183 | 3.08e-01 | 4.37e-02 | 0.940000 |
| REACTOME PROTEIN LOCALIZATION | 153 | 3.08e-01 | -4.77e-02 | 0.940000 |
| REACTOME SYNTHESIS OF 15 EICOSATETRAENOIC ACID DERIVATIVES | 6 | 3.08e-01 | 2.40e-01 | 0.940000 |
| REACTOME DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS | 15 | 3.09e-01 | -1.52e-01 | 0.940000 |
| REACTOME ASPARTATE AND ASPARAGINE METABOLISM | 11 | 3.11e-01 | 1.76e-01 | 0.940000 |
| REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES | 16 | 3.11e-01 | 1.46e-01 | 0.940000 |
| REACTOME POLB DEPENDENT LONG PATCH BASE EXCISION REPAIR | 8 | 3.12e-01 | 2.07e-01 | 0.940000 |
| REACTOME SIGNALING BY NTRK3 TRKC | 17 | 3.12e-01 | -1.42e-01 | 0.940000 |
| REACTOME C TYPE LECTIN RECEPTORS CLRS | 136 | 3.12e-01 | -5.02e-02 | 0.940000 |
| REACTOME ACTIVATED NTRK3 SIGNALS THROUGH PI3K | 6 | 3.12e-01 | -2.38e-01 | 0.940000 |
| REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | 81 | 3.13e-01 | 6.49e-02 | 0.940000 |
| REACTOME SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE | 91 | 3.13e-01 | -6.12e-02 | 0.940000 |
| REACTOME SIGNALING BY RETINOIC ACID | 41 | 3.13e-01 | -9.10e-02 | 0.940000 |
| REACTOME INACTIVATION OF CSF3 G CSF SIGNALING | 25 | 3.14e-01 | -1.16e-01 | 0.940000 |
| REACTOME LYSOSOME VESICLE BIOGENESIS | 33 | 3.15e-01 | 1.01e-01 | 0.940000 |
| REACTOME CLEC7A INFLAMMASOME PATHWAY | 6 | 3.16e-01 | 2.37e-01 | 0.940000 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FYN | 7 | 3.17e-01 | -2.19e-01 | 0.940000 |
| REACTOME NUCLEOTIDE EXCISION REPAIR | 107 | 3.17e-01 | 5.60e-02 | 0.940000 |
| REACTOME CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT | 19 | 3.18e-01 | -1.32e-01 | 0.940000 |
| REACTOME ESTROGEN DEPENDENT GENE EXPRESSION | 140 | 3.18e-01 | 4.89e-02 | 0.940000 |
| REACTOME PHENYLALANINE METABOLISM | 6 | 3.18e-01 | 2.36e-01 | 0.940000 |
| REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD4 | 15 | 3.18e-01 | 1.49e-01 | 0.940000 |
| REACTOME REGULATION OF NF KAPPA B SIGNALING | 17 | 3.19e-01 | 1.40e-01 | 0.940000 |
| REACTOME SIGNALING BY ALK | 26 | 3.19e-01 | 1.13e-01 | 0.940000 |
| REACTOME RNA POLYMERASE III TRANSCRIPTION | 41 | 3.19e-01 | 8.99e-02 | 0.940000 |
| REACTOME RUNX3 REGULATES YAP1 MEDIATED TRANSCRIPTION | 8 | 3.20e-01 | -2.03e-01 | 0.940000 |
| REACTOME NUCLEAR ENVELOPE NE REASSEMBLY | 74 | 3.20e-01 | 6.68e-02 | 0.940000 |
| REACTOME RECYCLING OF BILE ACIDS AND SALTS | 18 | 3.21e-01 | -1.35e-01 | 0.940000 |
| REACTOME ANDROGEN BIOSYNTHESIS | 11 | 3.22e-01 | -1.73e-01 | 0.940000 |
| REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | 11 | 3.22e-01 | -1.72e-01 | 0.940000 |
| REACTOME TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER | 76 | 3.22e-01 | 6.57e-02 | 0.940000 |
| REACTOME EICOSANOIDS | 12 | 3.22e-01 | -1.65e-01 | 0.940000 |
| REACTOME SODIUM COUPLED PHOSPHATE COTRANSPORTERS | 5 | 3.23e-01 | -2.55e-01 | 0.940000 |
| REACTOME EICOSANOID LIGAND BINDING RECEPTORS | 14 | 3.23e-01 | -1.53e-01 | 0.940000 |
| REACTOME CAMK IV MEDIATED PHOSPHORYLATION OF CREB | 10 | 3.23e-01 | 1.81e-01 | 0.940000 |
| REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | 20 | 3.23e-01 | 1.28e-01 | 0.940000 |
| REACTOME COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM | 21 | 3.23e-01 | 1.24e-01 | 0.940000 |
| REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY | 5 | 3.24e-01 | 2.55e-01 | 0.940000 |
| REACTOME GAP JUNCTION ASSEMBLY | 36 | 3.24e-01 | 9.50e-02 | 0.940000 |
| REACTOME TRANSPORT OF RCBL WITHIN THE BODY | 8 | 3.24e-01 | 2.01e-01 | 0.940000 |
| REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS | 28 | 3.25e-01 | -1.08e-01 | 0.940000 |
| REACTOME INTERLEUKIN 21 SIGNALING | 9 | 3.25e-01 | 1.89e-01 | 0.940000 |
| REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | 18 | 3.25e-01 | -1.34e-01 | 0.940000 |
| REACTOME MITOTIC SPINDLE CHECKPOINT | 109 | 3.26e-01 | 5.45e-02 | 0.940000 |
| REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL | 13 | 3.26e-01 | 1.57e-01 | 0.940000 |
| REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES | 7 | 3.27e-01 | 2.14e-01 | 0.941000 |
| REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3 | 679 | 3.28e-01 | 2.20e-02 | 0.941000 |
| REACTOME SERINE BIOSYNTHESIS | 9 | 3.30e-01 | 1.88e-01 | 0.943000 |
| REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES | 18 | 3.31e-01 | 1.32e-01 | 0.943000 |
| REACTOME P38MAPK EVENTS | 13 | 3.33e-01 | -1.55e-01 | 0.943000 |
| REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | 263 | 3.34e-01 | 3.46e-02 | 0.943000 |
| REACTOME GDP FUCOSE BIOSYNTHESIS | 6 | 3.34e-01 | 2.28e-01 | 0.943000 |
| REACTOME RHOJ GTPASE CYCLE | 51 | 3.35e-01 | 7.80e-02 | 0.943000 |
| REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 44 | 3.37e-01 | 8.37e-02 | 0.943000 |
| REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES | 34 | 3.37e-01 | -9.52e-02 | 0.943000 |
| REACTOME NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 19 | 3.37e-01 | 1.27e-01 | 0.943000 |
| REACTOME PRC2 METHYLATES HISTONES AND DNA | 65 | 3.37e-01 | -6.89e-02 | 0.943000 |
| REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION | 19 | 3.37e-01 | -1.27e-01 | 0.943000 |
| REACTOME BUDDING AND MATURATION OF HIV VIRION | 28 | 3.38e-01 | 1.05e-01 | 0.943000 |
| REACTOME RHOB GTPASE CYCLE | 67 | 3.39e-01 | 6.76e-02 | 0.943000 |
| REACTOME ION HOMEOSTASIS | 52 | 3.39e-01 | -7.67e-02 | 0.943000 |
| REACTOME RUNX3 REGULATES BCL2L11 BIM TRANSCRIPTION | 5 | 3.40e-01 | 2.47e-01 | 0.943000 |
| REACTOME PRE NOTCH PROCESSING IN GOLGI | 18 | 3.40e-01 | 1.30e-01 | 0.943000 |
| REACTOME PROTEIN REPAIR | 6 | 3.40e-01 | -2.25e-01 | 0.943000 |
| REACTOME CELL CELL COMMUNICATION | 126 | 3.41e-01 | -4.91e-02 | 0.943000 |
| REACTOME ORGANIC ANION TRANSPORT | 5 | 3.42e-01 | -2.45e-01 | 0.943000 |
| REACTOME ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT | 23 | 3.42e-01 | 1.14e-01 | 0.943000 |
| REACTOME STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES | 16 | 3.43e-01 | 1.37e-01 | 0.943000 |
| REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | 54 | 3.43e-01 | -7.46e-02 | 0.943000 |
| REACTOME FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES | 29 | 3.44e-01 | 1.02e-01 | 0.943000 |
| REACTOME STAT5 ACTIVATION | 7 | 3.44e-01 | -2.07e-01 | 0.943000 |
| REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS | 83 | 3.44e-01 | -6.01e-02 | 0.943000 |
| REACTOME RELAXIN RECEPTORS | 8 | 3.45e-01 | -1.93e-01 | 0.943000 |
| REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY DVL INTERACTING PROTEINS | 5 | 3.45e-01 | 2.44e-01 | 0.943000 |
| REACTOME HCMV INFECTION | 152 | 3.46e-01 | 4.43e-02 | 0.943000 |
| REACTOME CHYLOMICRON ASSEMBLY | 10 | 3.46e-01 | -1.72e-01 | 0.943000 |
| REACTOME METABOLISM OF FOLATE AND PTERINES | 17 | 3.48e-01 | 1.31e-01 | 0.943000 |
| REACTOME INTERLEUKIN 35 SIGNALLING | 12 | 3.48e-01 | 1.56e-01 | 0.943000 |
| REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV 1 INFECTION | 5 | 3.50e-01 | -2.42e-01 | 0.943000 |
| REACTOME SARS COV 1 HOST INTERACTIONS | 92 | 3.50e-01 | -5.64e-02 | 0.943000 |
| REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION | 145 | 3.51e-01 | -4.49e-02 | 0.943000 |
| REACTOME DISEASES OF PROGRAMMED CELL DEATH | 96 | 3.51e-01 | -5.50e-02 | 0.943000 |
| REACTOME PREVENTION OF PHAGOSOMAL LYSOSOMAL FUSION | 9 | 3.52e-01 | -1.79e-01 | 0.943000 |
| REACTOME MYOGENESIS | 29 | 3.52e-01 | -9.98e-02 | 0.943000 |
| REACTOME FORMATION OF AXIAL MESODERM | 14 | 3.54e-01 | 1.43e-01 | 0.943000 |
| REACTOME INTERLEUKIN 15 SIGNALING | 13 | 3.54e-01 | 1.48e-01 | 0.943000 |
| REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | 91 | 3.54e-01 | -5.62e-02 | 0.943000 |
| REACTOME NONHOMOLOGOUS END JOINING NHEJ | 64 | 3.56e-01 | 6.68e-02 | 0.943000 |
| REACTOME INTERFERON GAMMA SIGNALING | 88 | 3.56e-01 | 5.70e-02 | 0.943000 |
| REACTOME BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS | 10 | 3.56e-01 | 1.69e-01 | 0.943000 |
| REACTOME FATTY ACYL COA BIOSYNTHESIS | 36 | 3.56e-01 | -8.88e-02 | 0.943000 |
| REACTOME SIGNAL TRANSDUCTION BY L1 | 20 | 3.56e-01 | -1.19e-01 | 0.943000 |
| REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | 11 | 3.57e-01 | 1.60e-01 | 0.943000 |
| REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | 45 | 3.57e-01 | -7.94e-02 | 0.943000 |
| REACTOME FGFRL1 MODULATION OF FGFR1 SIGNALING | 13 | 3.57e-01 | 1.48e-01 | 0.943000 |
| REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING | 30 | 3.57e-01 | 9.71e-02 | 0.943000 |
| REACTOME SIGNALING BY LRP5 MUTANTS | 6 | 3.58e-01 | -2.17e-01 | 0.943000 |
| REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | 19 | 3.58e-01 | -1.22e-01 | 0.943000 |
| REACTOME SYNTHESIS OF PG | 8 | 3.58e-01 | -1.88e-01 | 0.943000 |
| REACTOME ATTACHMENT OF GPI ANCHOR TO UPAR | 7 | 3.62e-01 | -1.99e-01 | 0.949000 |
| REACTOME SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS | 12 | 3.62e-01 | -1.52e-01 | 0.949000 |
| REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS | 27 | 3.63e-01 | 1.01e-01 | 0.950000 |
| REACTOME SARS COV INFECTIONS | 392 | 3.63e-01 | 2.67e-02 | 0.950000 |
| REACTOME ACTIVATED NTRK3 SIGNALS THROUGH RAS | 8 | 3.64e-01 | -1.85e-01 | 0.950000 |
| REACTOME SEMA4D IN SEMAPHORIN SIGNALING | 24 | 3.65e-01 | -1.07e-01 | 0.950000 |
| REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1 | 16 | 3.65e-01 | 1.31e-01 | 0.950000 |
| REACTOME INTEGRATION OF ENERGY METABOLISM | 105 | 3.66e-01 | 5.10e-02 | 0.950000 |
| REACTOME G2 M CHECKPOINTS | 162 | 3.66e-01 | -4.11e-02 | 0.950000 |
| REACTOME RMTS METHYLATE HISTONE ARGININES | 72 | 3.70e-01 | 6.12e-02 | 0.957000 |
| REACTOME TOLL LIKE RECEPTOR CASCADES | 158 | 3.71e-01 | -4.12e-02 | 0.959000 |
| REACTOME RHOC GTPASE CYCLE | 71 | 3.72e-01 | 6.13e-02 | 0.959000 |
| REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING | 28 | 3.72e-01 | -9.75e-02 | 0.959000 |
| REACTOME DEFECTIVE CHST3 CAUSES SEDCJD | 7 | 3.74e-01 | -1.94e-01 | 0.961000 |
| REACTOME PHENYLALANINE AND TYROSINE METABOLISM | 11 | 3.74e-01 | -1.55e-01 | 0.961000 |
| REACTOME ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION | 28 | 3.75e-01 | -9.68e-02 | 0.961000 |
| REACTOME AMINE LIGAND BINDING RECEPTORS | 40 | 3.75e-01 | 8.10e-02 | 0.961000 |
| REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | 26 | 3.79e-01 | -9.97e-02 | 0.961000 |
| REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | 15 | 3.79e-01 | 1.31e-01 | 0.961000 |
| REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | 48 | 3.79e-01 | 7.34e-02 | 0.961000 |
| REACTOME CA2 PATHWAY | 62 | 3.80e-01 | 6.45e-02 | 0.961000 |
| REACTOME LRR FLII INTERACTING PROTEIN 1 LRRFIP1 ACTIVATES TYPE I IFN PRODUCTION | 5 | 3.80e-01 | 2.27e-01 | 0.961000 |
| REACTOME REGULATION OF TP53 EXPRESSION AND DEGRADATION | 37 | 3.81e-01 | 8.33e-02 | 0.961000 |
| REACTOME FREE FATTY ACID RECEPTORS | 5 | 3.81e-01 | 2.26e-01 | 0.961000 |
| REACTOME PI 3K CASCADE FGFR4 | 19 | 3.81e-01 | -1.16e-01 | 0.961000 |
| REACTOME TOLL LIKE RECEPTOR 9 TLR9 CASCADE | 100 | 3.82e-01 | 5.06e-02 | 0.961000 |
| REACTOME RAF INDEPENDENT MAPK1 3 ACTIVATION | 22 | 3.83e-01 | 1.08e-01 | 0.961000 |
| REACTOME RNA POLYMERASE I TRANSCRIPTION TERMINATION | 30 | 3.83e-01 | 9.20e-02 | 0.961000 |
| REACTOME DISSOLUTION OF FIBRIN CLOT | 13 | 3.84e-01 | -1.40e-01 | 0.961000 |
| REACTOME DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA | 77 | 3.84e-01 | 5.73e-02 | 0.961000 |
| REACTOME RHOF GTPASE CYCLE | 40 | 3.85e-01 | 7.94e-02 | 0.961000 |
| REACTOME NEUROTRANSMITTER CLEARANCE | 9 | 3.85e-01 | 1.67e-01 | 0.961000 |
| REACTOME RUNX3 REGULATES WNT SIGNALING | 8 | 3.86e-01 | -1.77e-01 | 0.961000 |
| REACTOME GPCR LIGAND BINDING | 444 | 3.86e-01 | -2.40e-02 | 0.961000 |
| REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | 160 | 3.88e-01 | 3.96e-02 | 0.961000 |
| REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | 11 | 3.88e-01 | 1.50e-01 | 0.961000 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES | 12 | 3.89e-01 | 1.44e-01 | 0.961000 |
| REACTOME CHL1 INTERACTIONS | 9 | 3.89e-01 | 1.66e-01 | 0.961000 |
| REACTOME NEUROTRANSMITTER RELEASE CYCLE | 48 | 3.90e-01 | -7.17e-02 | 0.961000 |
| REACTOME SHC MEDIATED CASCADE FGFR4 | 19 | 3.91e-01 | -1.14e-01 | 0.961000 |
| REACTOME AGGREPHAGY | 42 | 3.91e-01 | 7.65e-02 | 0.961000 |
| REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES | 10 | 3.91e-01 | -1.57e-01 | 0.961000 |
| REACTOME SIGNALING BY FGFR4 IN DISEASE | 11 | 3.92e-01 | -1.49e-01 | 0.961000 |
| REACTOME ENDOSOMAL VACUOLAR PATHWAY | 11 | 3.92e-01 | -1.49e-01 | 0.961000 |
| REACTOME ACTIVATION OF BH3 ONLY PROTEINS | 30 | 3.93e-01 | -9.02e-02 | 0.961000 |
| REACTOME ENDOGENOUS STEROLS | 26 | 3.93e-01 | -9.68e-02 | 0.961000 |
| REACTOME CHYLOMICRON REMODELING | 10 | 3.94e-01 | -1.56e-01 | 0.961000 |
| REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS | 312 | 3.98e-01 | -2.78e-02 | 0.961000 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH RAS | 9 | 3.99e-01 | -1.62e-01 | 0.961000 |
| REACTOME PHOSPHORYLATION OF EMI1 | 6 | 3.99e-01 | -1.99e-01 | 0.961000 |
| REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION | 23 | 3.99e-01 | -1.01e-01 | 0.961000 |
| REACTOME FRS MEDIATED FGFR2 SIGNALING | 24 | 4.00e-01 | 9.93e-02 | 0.961000 |
| REACTOME SIGNALING BY FGFR3 | 39 | 4.00e-01 | -7.79e-02 | 0.961000 |
| REACTOME RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS | 9 | 4.00e-01 | -1.62e-01 | 0.961000 |
| REACTOME GLUTATHIONE CONJUGATION | 33 | 4.01e-01 | 8.44e-02 | 0.961000 |
| REACTOME NEGATIVE REGULATION OF MAPK PATHWAY | 41 | 4.02e-01 | -7.57e-02 | 0.961000 |
| REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE | 11 | 4.02e-01 | 1.46e-01 | 0.961000 |
| REACTOME SHC1 EVENTS IN ERBB2 SIGNALING | 22 | 4.02e-01 | -1.03e-01 | 0.961000 |
| REACTOME RNA POLYMERASE I TRANSCRIPTION | 102 | 4.03e-01 | 4.79e-02 | 0.961000 |
| REACTOME DRUG MEDIATED INHIBITION OF CDK4 CDK6 ACTIVITY | 5 | 4.04e-01 | -2.16e-01 | 0.961000 |
| REACTOME CELL CELL JUNCTION ORGANIZATION | 64 | 4.04e-01 | -6.03e-02 | 0.961000 |
| REACTOME EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION | 27 | 4.04e-01 | -9.27e-02 | 0.961000 |
| REACTOME ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY | 5 | 4.06e-01 | -2.15e-01 | 0.961000 |
| REACTOME NEF MEDIATED CD4 DOWN REGULATION | 9 | 4.06e-01 | 1.60e-01 | 0.961000 |
| REACTOME CD22 MEDIATED BCR REGULATION | 5 | 4.06e-01 | -2.14e-01 | 0.961000 |
| REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX IN CANCER | 8 | 4.07e-01 | 1.69e-01 | 0.961000 |
| REACTOME GP1B IX V ACTIVATION SIGNALLING | 11 | 4.07e-01 | -1.44e-01 | 0.961000 |
| REACTOME RHOD GTPASE CYCLE | 49 | 4.07e-01 | 6.84e-02 | 0.961000 |
| REACTOME COPII MEDIATED VESICLE TRANSPORT | 66 | 4.07e-01 | 5.90e-02 | 0.961000 |
| REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | 38 | 4.08e-01 | 7.76e-02 | 0.961000 |
| REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | 13 | 4.09e-01 | -1.32e-01 | 0.961000 |
| REACTOME TRANSCRIPTIONAL REGULATION BY RUNX2 | 117 | 4.09e-01 | -4.42e-02 | 0.961000 |
| REACTOME INTERLEUKIN 27 SIGNALING | 11 | 4.10e-01 | 1.44e-01 | 0.961000 |
| REACTOME RSK ACTIVATION | 5 | 4.11e-01 | 2.12e-01 | 0.961000 |
| REACTOME IRE1ALPHA ACTIVATES CHAPERONES | 48 | 4.12e-01 | 6.84e-02 | 0.961000 |
| REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS | 100 | 4.13e-01 | -4.74e-02 | 0.961000 |
| REACTOME SARS COV 2 INFECTION | 281 | 4.14e-01 | 2.83e-02 | 0.961000 |
| REACTOME ATORVASTATIN ADME | 9 | 4.14e-01 | -1.57e-01 | 0.961000 |
| REACTOME RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK | 47 | 4.14e-01 | -6.88e-02 | 0.961000 |
| REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | 118 | 4.15e-01 | -4.34e-02 | 0.961000 |
| REACTOME NOD1 2 SIGNALING PATHWAY | 33 | 4.16e-01 | 8.19e-02 | 0.961000 |
| REACTOME NGF STIMULATED TRANSCRIPTION | 38 | 4.16e-01 | -7.62e-02 | 0.961000 |
| REACTOME UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN | 6 | 4.16e-01 | -1.92e-01 | 0.961000 |
| REACTOME INTERLEUKIN RECEPTOR SHC SIGNALING | 24 | 4.17e-01 | 9.57e-02 | 0.961000 |
| REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX | 9 | 4.17e-01 | -1.56e-01 | 0.961000 |
| REACTOME FORMATION OF PARAXIAL MESODERM | 22 | 4.17e-01 | -1.00e-01 | 0.961000 |
| REACTOME ABACAVIR TRANSMEMBRANE TRANSPORT | 5 | 4.17e-01 | 2.09e-01 | 0.961000 |
| REACTOME RESPIRATORY ELECTRON TRANSPORT | 90 | 4.17e-01 | -4.95e-02 | 0.961000 |
| REACTOME KERATAN SULFATE BIOSYNTHESIS | 28 | 4.17e-01 | -8.85e-02 | 0.961000 |
| REACTOME NONCANONICAL ACTIVATION OF NOTCH3 | 8 | 4.19e-01 | -1.65e-01 | 0.963000 |
| REACTOME METABOLISM OF AMINE DERIVED HORMONES | 17 | 4.20e-01 | -1.13e-01 | 0.964000 |
| REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER | 81 | 4.20e-01 | 5.18e-02 | 0.964000 |
| REACTOME METABOLISM OF NUCLEOTIDES | 94 | 4.22e-01 | -4.79e-02 | 0.966000 |
| REACTOME DEFECTIVE CHST14 CAUSES EDS MUSCULOCONTRACTURAL TYPE | 7 | 4.22e-01 | -1.75e-01 | 0.966000 |
| REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE | 5 | 4.24e-01 | -2.06e-01 | 0.966000 |
| REACTOME INSULIN PROCESSING | 24 | 4.25e-01 | -9.41e-02 | 0.966000 |
| REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING | 25 | 4.27e-01 | -9.17e-02 | 0.966000 |
| REACTOME FREE FATTY ACIDS REGULATE INSULIN SECRETION | 10 | 4.28e-01 | 1.45e-01 | 0.966000 |
| REACTOME NCAM1 INTERACTIONS | 41 | 4.28e-01 | 7.16e-02 | 0.966000 |
| REACTOME HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR IN THE PRESENCE OF LIGAND | 55 | 4.29e-01 | 6.17e-02 | 0.966000 |
| REACTOME FCERI MEDIATED MAPK ACTIVATION | 32 | 4.29e-01 | -8.08e-02 | 0.966000 |
| REACTOME REGULATION OF PTEN LOCALIZATION | 8 | 4.30e-01 | -1.61e-01 | 0.966000 |
| REACTOME VITAMINS | 6 | 4.30e-01 | 1.86e-01 | 0.966000 |
| REACTOME SHC1 EVENTS IN EGFR SIGNALING | 14 | 4.30e-01 | -1.22e-01 | 0.966000 |
| REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | 23 | 4.30e-01 | -9.50e-02 | 0.966000 |
| REACTOME ARMS MEDIATED ACTIVATION | 7 | 4.31e-01 | 1.72e-01 | 0.966000 |
| REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | 27 | 4.31e-01 | 8.76e-02 | 0.966000 |
| REACTOME OPIOID SIGNALLING | 89 | 4.31e-01 | -4.83e-02 | 0.966000 |
| REACTOME PHOSPHORYLATION OF THE APC C | 20 | 4.32e-01 | 1.02e-01 | 0.967000 |
| REACTOME RUNX2 REGULATES CHONDROCYTE MATURATION | 5 | 4.34e-01 | 2.02e-01 | 0.969000 |
| REACTOME ACTIVATION OF RAS IN B CELLS | 5 | 4.34e-01 | -2.02e-01 | 0.969000 |
| REACTOME EPHB MEDIATED FORWARD SIGNALING | 41 | 4.34e-01 | -7.06e-02 | 0.969000 |
| REACTOME HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS | 7 | 4.36e-01 | -1.70e-01 | 0.970000 |
| REACTOME NEF MEDIATED CD8 DOWN REGULATION | 7 | 4.36e-01 | 1.70e-01 | 0.970000 |
| REACTOME MODULATION BY MTB OF HOST IMMUNE SYSTEM | 6 | 4.37e-01 | -1.83e-01 | 0.970000 |
| REACTOME SYNTHESIS OF PE | 13 | 4.37e-01 | -1.24e-01 | 0.970000 |
| REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE | 52 | 4.38e-01 | 6.22e-02 | 0.970000 |
| REACTOME REGULATION OF BETA CELL DEVELOPMENT | 41 | 4.40e-01 | 6.97e-02 | 0.970000 |
| REACTOME SUMOYLATION OF RNA BINDING PROTEINS | 47 | 4.40e-01 | 6.51e-02 | 0.970000 |
| REACTOME MRNA CAPPING | 28 | 4.41e-01 | 8.41e-02 | 0.970000 |
| REACTOME PROTON COUPLED MONOCARBOXYLATE TRANSPORT | 6 | 4.42e-01 | 1.81e-01 | 0.970000 |
| REACTOME MISCELLANEOUS SUBSTRATES | 12 | 4.43e-01 | -1.28e-01 | 0.970000 |
| REACTOME VISUAL PHOTOTRANSDUCTION | 93 | 4.44e-01 | 4.60e-02 | 0.970000 |
| REACTOME CATION COUPLED CHLORIDE COTRANSPORTERS | 7 | 4.45e-01 | 1.67e-01 | 0.970000 |
| REACTOME PTK6 PROMOTES HIF1A STABILIZATION | 6 | 4.46e-01 | -1.80e-01 | 0.970000 |
| REACTOME MHC CLASS II ANTIGEN PRESENTATION | 121 | 4.46e-01 | 4.01e-02 | 0.970000 |
| REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A | 26 | 4.48e-01 | 8.60e-02 | 0.970000 |
| REACTOME INTERLEUKIN 37 SIGNALING | 20 | 4.48e-01 | 9.80e-02 | 0.970000 |
| REACTOME WAX AND PLASMALOGEN BIOSYNTHESIS | 5 | 4.49e-01 | -1.96e-01 | 0.970000 |
| REACTOME LINOLEIC ACID LA METABOLISM | 7 | 4.50e-01 | 1.65e-01 | 0.970000 |
| REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS | 299 | 4.52e-01 | 2.53e-02 | 0.970000 |
| REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA | 28 | 4.52e-01 | -8.22e-02 | 0.970000 |
| REACTOME EPH EPHRIN MEDIATED REPULSION OF CELLS | 50 | 4.53e-01 | 6.14e-02 | 0.970000 |
| REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE | 19 | 4.53e-01 | 9.95e-02 | 0.970000 |
| REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER | 28 | 4.53e-01 | 8.19e-02 | 0.970000 |
| REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION | 12 | 4.54e-01 | 1.25e-01 | 0.970000 |
| REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | 17 | 4.55e-01 | -1.05e-01 | 0.970000 |
| REACTOME NEUROTOXICITY OF CLOSTRIDIUM TOXINS | 10 | 4.55e-01 | -1.37e-01 | 0.970000 |
| REACTOME REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION | 84 | 4.56e-01 | 4.71e-02 | 0.970000 |
| REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE | 22 | 4.57e-01 | -9.15e-02 | 0.970000 |
| REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX | 57 | 4.58e-01 | 5.68e-02 | 0.970000 |
| REACTOME CELLULAR RESPONSES TO STIMULI | 779 | 4.59e-01 | 1.56e-02 | 0.970000 |
| REACTOME DIGESTION OF DIETARY CARBOHYDRATE | 6 | 4.59e-01 | -1.74e-01 | 0.970000 |
| REACTOME POTENTIAL THERAPEUTICS FOR SARS | 92 | 4.60e-01 | 4.46e-02 | 0.970000 |
| REACTOME CD28 DEPENDENT VAV1 PATHWAY | 11 | 4.60e-01 | -1.29e-01 | 0.970000 |
| REACTOME REGULATION OF NPAS4 GENE TRANSCRIPTION | 5 | 4.61e-01 | -1.91e-01 | 0.970000 |
| REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | 11 | 4.61e-01 | 1.28e-01 | 0.970000 |
| REACTOME ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS | 7 | 4.62e-01 | 1.60e-01 | 0.970000 |
| REACTOME INWARDLY RECTIFYING K CHANNELS | 35 | 4.63e-01 | -7.17e-02 | 0.970000 |
| REACTOME ASPARAGINE N LINKED GLYCOSYLATION | 299 | 4.63e-01 | 2.47e-02 | 0.970000 |
| REACTOME INTERLEUKIN 17 SIGNALING | 66 | 4.64e-01 | 5.21e-02 | 0.970000 |
| REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX | 19 | 4.64e-01 | 9.70e-02 | 0.970000 |
| REACTOME FATTY ACID METABOLISM | 170 | 4.67e-01 | 3.23e-02 | 0.970000 |
| REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF | 17 | 4.68e-01 | 1.02e-01 | 0.970000 |
| REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1 | 25 | 4.69e-01 | -8.37e-02 | 0.970000 |
| REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS | 5 | 4.69e-01 | -1.87e-01 | 0.970000 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS | 5 | 4.71e-01 | 1.86e-01 | 0.970000 |
| REACTOME SUMO IS TRANSFERRED FROM E1 TO E2 UBE2I UBC9 | 7 | 4.72e-01 | 1.57e-01 | 0.970000 |
| REACTOME SARS COV 2 HOST INTERACTIONS | 191 | 4.72e-01 | 3.02e-02 | 0.970000 |
| REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT | 222 | 4.72e-01 | -2.80e-02 | 0.970000 |
| REACTOME DISEASES OF CARBOHYDRATE METABOLISM | 31 | 4.73e-01 | 7.45e-02 | 0.970000 |
| REACTOME BILE ACID AND BILE SALT METABOLISM | 45 | 4.74e-01 | -6.17e-02 | 0.970000 |
| REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | 51 | 4.76e-01 | -5.77e-02 | 0.970000 |
| REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX | 91 | 4.76e-01 | 4.32e-02 | 0.970000 |
| REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON | 17 | 4.77e-01 | 9.97e-02 | 0.970000 |
| REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | 9 | 4.77e-01 | 1.37e-01 | 0.970000 |
| REACTOME GASTRULATION | 49 | 4.77e-01 | -5.87e-02 | 0.970000 |
| REACTOME TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS | 29 | 4.79e-01 | -7.60e-02 | 0.970000 |
| REACTOME ACTIVATION OF NIMA KINASES NEK9 NEK6 NEK7 | 7 | 4.79e-01 | -1.54e-01 | 0.970000 |
| REACTOME INITIATION OF NUCLEAR ENVELOPE NE REFORMATION | 18 | 4.80e-01 | 9.62e-02 | 0.970000 |
| REACTOME CGMP EFFECTS | 16 | 4.80e-01 | -1.02e-01 | 0.970000 |
| REACTOME DRUG ADME | 103 | 4.80e-01 | -4.03e-02 | 0.970000 |
| REACTOME CD209 DC SIGN SIGNALING | 20 | 4.81e-01 | 9.11e-02 | 0.970000 |
| REACTOME HIV LIFE CYCLE | 145 | 4.81e-01 | 3.39e-02 | 0.970000 |
| REACTOME SIGNALING BY HEDGEHOG | 148 | 4.81e-01 | -3.36e-02 | 0.970000 |
| REACTOME RAC2 GTPASE CYCLE | 81 | 4.81e-01 | 4.52e-02 | 0.970000 |
| REACTOME DEFECTS IN VITAMIN AND COFACTOR METABOLISM | 21 | 4.81e-01 | 8.87e-02 | 0.970000 |
| REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3 | 59 | 4.82e-01 | -5.29e-02 | 0.970000 |
| REACTOME GLYCOSPHINGOLIPID METABOLISM | 39 | 4.82e-01 | 6.50e-02 | 0.970000 |
| REACTOME MET ACTIVATES RAP1 AND RAC1 | 11 | 4.83e-01 | -1.22e-01 | 0.970000 |
| REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | 111 | 4.83e-01 | -3.85e-02 | 0.970000 |
| REACTOME NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 22 | 4.84e-01 | -8.63e-02 | 0.970000 |
| REACTOME DEFECTS IN COBALAMIN B12 METABOLISM | 13 | 4.84e-01 | 1.12e-01 | 0.970000 |
| REACTOME TRAFFICKING OF AMPA RECEPTORS | 29 | 4.84e-01 | 7.50e-02 | 0.970000 |
| REACTOME RIPK1 MEDIATED REGULATED NECROSIS | 30 | 4.85e-01 | -7.37e-02 | 0.970000 |
| REACTOME SYNTHESIS OF DNA | 119 | 4.85e-01 | -3.70e-02 | 0.970000 |
| REACTOME FOXO MEDIATED TRANSCRIPTION | 65 | 4.86e-01 | 5.00e-02 | 0.970000 |
| REACTOME RRNA MODIFICATION IN THE MITOCHONDRION | 6 | 4.86e-01 | -1.64e-01 | 0.970000 |
| REACTOME G PROTEIN BETA GAMMA SIGNALLING | 30 | 4.87e-01 | 7.34e-02 | 0.970000 |
| REACTOME DEADENYLATION DEPENDENT MRNA DECAY | 56 | 4.87e-01 | 5.37e-02 | 0.970000 |
| REACTOME ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS | 24 | 4.87e-01 | -8.20e-02 | 0.970000 |
| REACTOME INOSITOL PHOSPHATE METABOLISM | 45 | 4.87e-01 | 5.99e-02 | 0.970000 |
| REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION | 60 | 4.88e-01 | -5.18e-02 | 0.970000 |
| REACTOME ARACHIDONATE PRODUCTION FROM DAG | 5 | 4.89e-01 | -1.79e-01 | 0.970000 |
| REACTOME SYNAPTIC ADHESION LIKE MOLECULES | 19 | 4.89e-01 | -9.16e-02 | 0.970000 |
| REACTOME ACTIVATION OF PPARGC1A PGC 1ALPHA BY PHOSPHORYLATION | 10 | 4.90e-01 | 1.26e-01 | 0.970000 |
| REACTOME SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS | 14 | 4.91e-01 | 1.06e-01 | 0.970000 |
| REACTOME DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B | 7 | 4.91e-01 | 1.50e-01 | 0.970000 |
| REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES | 29 | 4.92e-01 | 7.37e-02 | 0.970000 |
| REACTOME CONSTITUTIVE SIGNALING BY EGFRVIII | 15 | 4.93e-01 | -1.02e-01 | 0.970000 |
| REACTOME ESTABLISHMENT OF SISTER CHROMATID COHESION | 9 | 4.94e-01 | -1.32e-01 | 0.970000 |
| REACTOME SIGNALING BY ERYTHROPOIETIN | 25 | 4.95e-01 | 7.88e-02 | 0.970000 |
| REACTOME SIGNALING BY MAPK MUTANTS | 6 | 4.96e-01 | 1.61e-01 | 0.970000 |
| REACTOME REGULATION OF BACH1 ACTIVITY | 11 | 4.96e-01 | -1.19e-01 | 0.970000 |
| REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM | 23 | 4.96e-01 | 8.20e-02 | 0.970000 |
| REACTOME MYD88 INDEPENDENT TLR4 CASCADE | 103 | 4.97e-01 | 3.87e-02 | 0.970000 |
| REACTOME RAB GERANYLGERANYLATION | 57 | 4.97e-01 | -5.20e-02 | 0.970000 |
| REACTOME DEFECTIVE CHST6 CAUSES MCDC1 | 8 | 4.97e-01 | -1.39e-01 | 0.970000 |
| REACTOME SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION | 8 | 4.98e-01 | -1.38e-01 | 0.970000 |
| REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION | 9 | 4.98e-01 | -1.30e-01 | 0.970000 |
| REACTOME CYCLIN D ASSOCIATED EVENTS IN G1 | 46 | 4.98e-01 | -5.77e-02 | 0.970000 |
| REACTOME DEFECTIVE RIPK1 MEDIATED REGULATED NECROSIS | 7 | 4.99e-01 | -1.48e-01 | 0.970000 |
| REACTOME KEAP1 NFE2L2 PATHWAY | 104 | 5.00e-01 | -3.83e-02 | 0.970000 |
| REACTOME ACTIVATION OF CASPASES THROUGH APOPTOSOME MEDIATED CLEAVAGE | 5 | 5.00e-01 | -1.74e-01 | 0.970000 |
| REACTOME GAP JUNCTION TRAFFICKING AND REGULATION | 49 | 5.01e-01 | 5.56e-02 | 0.970000 |
| REACTOME HS GAG DEGRADATION | 19 | 5.01e-01 | -8.91e-02 | 0.970000 |
| REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1 | 229 | 5.02e-01 | 2.58e-02 | 0.970000 |
| REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | 123 | 5.02e-01 | -3.51e-02 | 0.970000 |
| REACTOME SIGNALING BY NOTCH1 | 69 | 5.02e-01 | 4.67e-02 | 0.970000 |
| REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK | 17 | 5.03e-01 | -9.39e-02 | 0.970000 |
| REACTOME O LINKED GLYCOSYLATION OF MUCINS | 61 | 5.03e-01 | -4.95e-02 | 0.970000 |
| REACTOME EFFECTS OF PIP2 HYDROLYSIS | 26 | 5.04e-01 | -7.58e-02 | 0.970000 |
| REACTOME CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA | 63 | 5.04e-01 | 4.87e-02 | 0.970000 |
| REACTOME METABOLISM OF INGESTED SEMET SEC MESEC INTO H2SE | 7 | 5.04e-01 | 1.46e-01 | 0.970000 |
| REACTOME SIGNALING BY RNF43 MUTANTS | 8 | 5.04e-01 | 1.36e-01 | 0.970000 |
| REACTOME DEFECTIVE F9 ACTIVATION | 5 | 5.04e-01 | 1.72e-01 | 0.970000 |
| REACTOME NEGATIVE REGULATION OF ACTIVITY OF TFAP2 AP 2 FAMILY TRANSCRIPTION FACTORS | 10 | 5.05e-01 | -1.22e-01 | 0.970000 |
| REACTOME DEFECTIVE CHSY1 CAUSES TPBS | 7 | 5.05e-01 | -1.45e-01 | 0.970000 |
| REACTOME TELOMERE MAINTENANCE | 106 | 5.06e-01 | 3.74e-02 | 0.970000 |
| REACTOME HEDGEHOG OFF STATE | 111 | 5.06e-01 | -3.66e-02 | 0.970000 |
| REACTOME TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX | 10 | 5.06e-01 | -1.21e-01 | 0.970000 |
| REACTOME TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE | 10 | 5.07e-01 | -1.21e-01 | 0.970000 |
| REACTOME ACYL CHAIN REMODELING OF DAG AND TAG | 5 | 5.07e-01 | -1.71e-01 | 0.970000 |
| REACTOME RAS PROCESSING | 22 | 5.08e-01 | -8.16e-02 | 0.970000 |
| REACTOME PEXOPHAGY | 11 | 5.08e-01 | -1.15e-01 | 0.970000 |
| REACTOME SMOOTH MUSCLE CONTRACTION | 43 | 5.09e-01 | 5.82e-02 | 0.970000 |
| REACTOME CELLULAR HEXOSE TRANSPORT | 21 | 5.10e-01 | -8.31e-02 | 0.970000 |
| REACTOME DEFENSINS | 33 | 5.11e-01 | 6.61e-02 | 0.970000 |
| REACTOME CONDENSATION OF PROMETAPHASE CHROMOSOMES | 11 | 5.11e-01 | 1.14e-01 | 0.970000 |
| REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS | 66 | 5.12e-01 | 4.67e-02 | 0.970000 |
| REACTOME EARLY SARS COV 2 INFECTION EVENTS | 34 | 5.12e-01 | 6.50e-02 | 0.970000 |
| REACTOME ION TRANSPORT BY P TYPE ATPASES | 51 | 5.12e-01 | 5.30e-02 | 0.970000 |
| REACTOME TRANSPORT OF FATTY ACIDS | 8 | 5.13e-01 | 1.34e-01 | 0.970000 |
| REACTOME RESOLUTION OF ABASIC SITES AP SITES | 38 | 5.13e-01 | 6.13e-02 | 0.970000 |
| REACTOME CD28 CO STIMULATION | 32 | 5.14e-01 | 6.67e-02 | 0.970000 |
| REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION | 84 | 5.14e-01 | -4.12e-02 | 0.970000 |
| REACTOME SIGNALLING TO P38 VIA RIT AND RIN | 5 | 5.16e-01 | -1.68e-01 | 0.970000 |
| REACTOME HSF1 DEPENDENT TRANSACTIVATION | 37 | 5.16e-01 | 6.18e-02 | 0.970000 |
| REACTOME NS1 MEDIATED EFFECTS ON HOST PATHWAYS | 41 | 5.16e-01 | 5.87e-02 | 0.970000 |
| REACTOME RHO GTPASES ACTIVATE PKNS | 86 | 5.17e-01 | -4.05e-02 | 0.971000 |
| REACTOME METHYLATION | 14 | 5.18e-01 | 9.99e-02 | 0.971000 |
| REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY | 14 | 5.19e-01 | 9.95e-02 | 0.972000 |
| REACTOME CTLA4 INHIBITORY SIGNALING | 21 | 5.20e-01 | 8.10e-02 | 0.972000 |
| REACTOME DIGESTION OF DIETARY LIPID | 7 | 5.21e-01 | 1.40e-01 | 0.972000 |
| REACTOME RHO GTPASES ACTIVATE IQGAPS | 31 | 5.21e-01 | 6.66e-02 | 0.972000 |
| REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH | 62 | 5.21e-01 | 4.71e-02 | 0.972000 |
| REACTOME ACETYLCHOLINE REGULATES INSULIN SECRETION | 10 | 5.23e-01 | 1.17e-01 | 0.974000 |
| REACTOME DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15 | 8 | 5.24e-01 | -1.30e-01 | 0.975000 |
| REACTOME COMMON PATHWAY OF FIBRIN CLOT FORMATION | 21 | 5.26e-01 | -7.99e-02 | 0.975000 |
| REACTOME LONG TERM POTENTIATION | 22 | 5.27e-01 | -7.80e-02 | 0.975000 |
| REACTOME ACTIVATION OF C3 AND C5 | 6 | 5.27e-01 | -1.49e-01 | 0.975000 |
| REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES | 15 | 5.28e-01 | -9.42e-02 | 0.975000 |
| REACTOME CELLULAR RESPONSE TO STARVATION | 147 | 5.30e-01 | -3.00e-02 | 0.975000 |
| REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES | 11 | 5.30e-01 | -1.09e-01 | 0.975000 |
| REACTOME METABOLISM OF STEROIDS | 150 | 5.31e-01 | 2.96e-02 | 0.975000 |
| REACTOME PYRIMIDINE CATABOLISM | 12 | 5.32e-01 | -1.04e-01 | 0.975000 |
| REACTOME TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS | 82 | 5.32e-01 | 3.99e-02 | 0.975000 |
| REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING | 32 | 5.32e-01 | -6.38e-02 | 0.975000 |
| REACTOME MYOCLONIC EPILEPSY OF LAFORA | 9 | 5.34e-01 | -1.20e-01 | 0.975000 |
| REACTOME RECYCLING OF EIF2 GDP | 7 | 5.34e-01 | 1.36e-01 | 0.975000 |
| REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES | 39 | 5.35e-01 | -5.74e-02 | 0.975000 |
| REACTOME METABOLISM OF LIPIDS | 709 | 5.36e-01 | 1.36e-02 | 0.975000 |
| REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | 12 | 5.37e-01 | -1.03e-01 | 0.975000 |
| REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | 21 | 5.38e-01 | 7.77e-02 | 0.975000 |
| REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | 24 | 5.38e-01 | -7.26e-02 | 0.975000 |
| REACTOME SIGNALING BY FGFR1 | 49 | 5.38e-01 | -5.08e-02 | 0.975000 |
| REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS | 46 | 5.39e-01 | -5.23e-02 | 0.975000 |
| REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND | 14 | 5.39e-01 | 9.47e-02 | 0.975000 |
| REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR4 | 14 | 5.40e-01 | -9.46e-02 | 0.975000 |
| REACTOME COSTIMULATION BY THE CD28 FAMILY | 64 | 5.41e-01 | 4.42e-02 | 0.975000 |
| REACTOME INTERLEUKIN 10 SIGNALING | 43 | 5.41e-01 | -5.39e-02 | 0.975000 |
| REACTOME TRANSPORT OF SMALL MOLECULES | 697 | 5.41e-01 | -1.36e-02 | 0.975000 |
| REACTOME ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS | 5 | 5.43e-01 | 1.57e-01 | 0.975000 |
| REACTOME VITAMIN C ASCORBATE METABOLISM | 8 | 5.43e-01 | 1.24e-01 | 0.975000 |
| REACTOME METALLOTHIONEINS BIND METALS | 11 | 5.43e-01 | -1.06e-01 | 0.975000 |
| REACTOME CELL JUNCTION ORGANIZATION | 89 | 5.43e-01 | -3.73e-02 | 0.975000 |
| REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | 22 | 5.44e-01 | 7.48e-02 | 0.975000 |
| REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET | 8 | 5.45e-01 | -1.24e-01 | 0.975000 |
| REACTOME RIP MEDIATED NFKB ACTIVATION VIA ZBP1 | 16 | 5.45e-01 | 8.74e-02 | 0.975000 |
| REACTOME DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS | 19 | 5.45e-01 | -8.01e-02 | 0.975000 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS | 12 | 5.46e-01 | 1.01e-01 | 0.975000 |
| REACTOME DEUBIQUITINATION | 260 | 5.46e-01 | 2.18e-02 | 0.975000 |
| REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION | 42 | 5.46e-01 | 5.38e-02 | 0.975000 |
| REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL | 58 | 5.47e-01 | 4.57e-02 | 0.975000 |
| REACTOME CALCINEURIN ACTIVATES NFAT | 9 | 5.48e-01 | 1.16e-01 | 0.975000 |
| REACTOME SUMOYLATION OF IMMUNE RESPONSE PROTEINS | 10 | 5.48e-01 | 1.10e-01 | 0.975000 |
| REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING | 12 | 5.49e-01 | 9.98e-02 | 0.975000 |
| REACTOME TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS | 26 | 5.49e-01 | -6.78e-02 | 0.975000 |
| REACTOME LTC4 CYSLTR MEDIATED IL4 PRODUCTION | 6 | 5.50e-01 | 1.41e-01 | 0.975000 |
| REACTOME TBC RABGAPS | 40 | 5.50e-01 | 5.46e-02 | 0.975000 |
| REACTOME GLYCOLYSIS | 70 | 5.51e-01 | 4.13e-02 | 0.975000 |
| REACTOME HDMS DEMETHYLATE HISTONES | 40 | 5.51e-01 | 5.45e-02 | 0.975000 |
| REACTOME VOLTAGE GATED POTASSIUM CHANNELS | 42 | 5.51e-01 | -5.31e-02 | 0.975000 |
| REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | 28 | 5.53e-01 | 6.48e-02 | 0.975000 |
| REACTOME INSULIN RECEPTOR RECYCLING | 29 | 5.53e-01 | 6.36e-02 | 0.975000 |
| REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES | 34 | 5.54e-01 | -5.87e-02 | 0.975000 |
| REACTOME G PROTEIN MEDIATED EVENTS | 53 | 5.54e-01 | 4.69e-02 | 0.975000 |
| REACTOME TRANSLESION SYNTHESIS BY POLH | 19 | 5.55e-01 | -7.83e-02 | 0.975000 |
| REACTOME NUCLEAR SIGNALING BY ERBB4 | 32 | 5.55e-01 | -6.03e-02 | 0.975000 |
| REACTOME PHASE II CONJUGATION OF COMPOUNDS | 102 | 5.55e-01 | 3.38e-02 | 0.975000 |
| REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | 16 | 5.56e-01 | -8.51e-02 | 0.975000 |
| REACTOME IRON UPTAKE AND TRANSPORT | 56 | 5.56e-01 | -4.55e-02 | 0.975000 |
| REACTOME PYRUVATE METABOLISM | 29 | 5.59e-01 | 6.28e-02 | 0.978000 |
| REACTOME INFLAMMASOMES | 21 | 5.59e-01 | -7.36e-02 | 0.978000 |
| REACTOME BINDING OF TCF LEF CTNNB1 TO TARGET GENE PROMOTERS | 8 | 5.59e-01 | -1.19e-01 | 0.978000 |
| REACTOME MISMATCH REPAIR | 15 | 5.61e-01 | 8.67e-02 | 0.979000 |
| REACTOME LDL REMODELING | 6 | 5.62e-01 | -1.37e-01 | 0.979000 |
| REACTOME PRE NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM | 6 | 5.62e-01 | 1.37e-01 | 0.979000 |
| REACTOME ESR MEDIATED SIGNALING | 210 | 5.62e-01 | 2.32e-02 | 0.979000 |
| REACTOME PI 3K CASCADE FGFR3 | 17 | 5.64e-01 | -8.09e-02 | 0.979000 |
| REACTOME G ALPHA Z SIGNALLING EVENTS | 48 | 5.67e-01 | -4.78e-02 | 0.979000 |
| REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS | 6 | 5.67e-01 | 1.35e-01 | 0.979000 |
| REACTOME RRNA PROCESSING | 192 | 5.67e-01 | -2.40e-02 | 0.979000 |
| REACTOME HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS | 9 | 5.68e-01 | -1.10e-01 | 0.979000 |
| REACTOME LIGAND RECEPTOR INTERACTIONS | 8 | 5.69e-01 | 1.16e-01 | 0.979000 |
| REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS | 12 | 5.69e-01 | 9.50e-02 | 0.979000 |
| REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES | 14 | 5.69e-01 | 8.79e-02 | 0.979000 |
| REACTOME NOSTRIN MEDIATED ENOS TRAFFICKING | 5 | 5.70e-01 | -1.47e-01 | 0.979000 |
| REACTOME RESOLUTION OF D LOOP STRUCTURES | 33 | 5.70e-01 | 5.71e-02 | 0.979000 |
| REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | 31 | 5.70e-01 | -5.89e-02 | 0.979000 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST | 14 | 5.70e-01 | 8.76e-02 | 0.979000 |
| REACTOME S PHASE | 159 | 5.72e-01 | -2.60e-02 | 0.979000 |
| REACTOME LAGGING STRAND SYNTHESIS | 19 | 5.74e-01 | 7.44e-02 | 0.979000 |
| REACTOME HS GAG BIOSYNTHESIS | 28 | 5.74e-01 | 6.13e-02 | 0.979000 |
| REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES | 77 | 5.75e-01 | -3.70e-02 | 0.979000 |
| REACTOME ROLE OF ABL IN ROBO SLIT SIGNALING | 8 | 5.76e-01 | 1.14e-01 | 0.979000 |
| REACTOME DERMATAN SULFATE BIOSYNTHESIS | 10 | 5.76e-01 | -1.02e-01 | 0.979000 |
| REACTOME SHC MEDIATED CASCADE FGFR3 | 17 | 5.77e-01 | -7.82e-02 | 0.979000 |
| REACTOME FGFR2C LIGAND BINDING AND ACTIVATION | 12 | 5.77e-01 | -9.30e-02 | 0.979000 |
| REACTOME PURINE SALVAGE | 12 | 5.77e-01 | -9.30e-02 | 0.979000 |
| REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS | 17 | 5.77e-01 | -7.81e-02 | 0.979000 |
| REACTOME SIGNALING BY FGFR IN DISEASE | 62 | 5.78e-01 | 4.09e-02 | 0.979000 |
| REACTOME G ALPHA I SIGNALLING EVENTS | 304 | 5.78e-01 | -1.85e-02 | 0.979000 |
| REACTOME RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION | 8 | 5.79e-01 | 1.13e-01 | 0.979000 |
| REACTOME TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA | 36 | 5.79e-01 | -5.35e-02 | 0.979000 |
| REACTOME DNA DOUBLE STRAND BREAK RESPONSE | 74 | 5.79e-01 | 3.73e-02 | 0.979000 |
| REACTOME LOSS OF FUNCTION OF SMAD2 3 IN CANCER | 7 | 5.79e-01 | 1.21e-01 | 0.979000 |
| REACTOME EXTRA NUCLEAR ESTROGEN SIGNALING | 74 | 5.80e-01 | -3.72e-02 | 0.979000 |
| REACTOME TRP CHANNELS | 27 | 5.82e-01 | -6.12e-02 | 0.979000 |
| REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | 62 | 5.84e-01 | 4.03e-02 | 0.979000 |
| REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS | 33 | 5.84e-01 | -5.51e-02 | 0.979000 |
| REACTOME HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE | 43 | 5.84e-01 | 4.82e-02 | 0.979000 |
| REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | 14 | 5.85e-01 | 8.43e-02 | 0.979000 |
| REACTOME REGULATION OF NPAS4 MRNA TRANSLATION | 9 | 5.85e-01 | 1.05e-01 | 0.979000 |
| REACTOME REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR | 11 | 5.86e-01 | 9.50e-02 | 0.979000 |
| REACTOME SIGNALING BY INSULIN RECEPTOR | 80 | 5.86e-01 | 3.52e-02 | 0.979000 |
| REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | 15 | 5.87e-01 | 8.09e-02 | 0.979000 |
| REACTOME BASIGIN INTERACTIONS | 24 | 5.89e-01 | -6.38e-02 | 0.979000 |
| REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS | 63 | 5.89e-01 | -3.94e-02 | 0.979000 |
| REACTOME AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY | 8 | 5.90e-01 | 1.10e-01 | 0.979000 |
| REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2 | 17 | 5.91e-01 | 7.54e-02 | 0.979000 |
| REACTOME PEROXISOMAL PROTEIN IMPORT | 62 | 5.91e-01 | 3.95e-02 | 0.979000 |
| REACTOME BETA OXIDATION OF PRISTANOYL COA | 9 | 5.91e-01 | 1.03e-01 | 0.979000 |
| REACTOME HIV ELONGATION ARREST AND RECOVERY | 33 | 5.92e-01 | 5.39e-02 | 0.979000 |
| REACTOME CHYLOMICRON CLEARANCE | 5 | 5.93e-01 | -1.38e-01 | 0.979000 |
| REACTOME PROSTANOID LIGAND RECEPTORS | 9 | 5.93e-01 | -1.03e-01 | 0.979000 |
| REACTOME FASL CD95L SIGNALING | 5 | 5.93e-01 | -1.38e-01 | 0.979000 |
| REACTOME CARGO CONCENTRATION IN THE ER | 32 | 5.94e-01 | -5.44e-02 | 0.979000 |
| REACTOME G PROTEIN ACTIVATION | 24 | 5.94e-01 | -6.28e-02 | 0.979000 |
| REACTOME DIGESTION | 17 | 5.95e-01 | -7.44e-02 | 0.979000 |
| REACTOME KINESINS | 59 | 5.95e-01 | 4.00e-02 | 0.979000 |
| REACTOME PHASE 4 RESTING MEMBRANE POTENTIAL | 19 | 5.95e-01 | -7.04e-02 | 0.979000 |
| REACTOME COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING | 38 | 5.96e-01 | -4.97e-02 | 0.979000 |
| REACTOME MITOTIC G2 G2 M PHASES | 194 | 5.98e-01 | 2.20e-02 | 0.979000 |
| REACTOME SULFUR AMINO ACID METABOLISM | 27 | 5.98e-01 | 5.86e-02 | 0.979000 |
| REACTOME SIGNALING BY VEGF | 102 | 5.99e-01 | 3.01e-02 | 0.979000 |
| REACTOME METABOLISM OF VITAMINS AND COFACTORS | 185 | 5.99e-01 | 2.24e-02 | 0.979000 |
| REACTOME ORGANIC ANION TRANSPORTERS | 10 | 5.99e-01 | 9.59e-02 | 0.979000 |
| REACTOME P75NTR REGULATES AXONOGENESIS | 9 | 6.00e-01 | -1.01e-01 | 0.979000 |
| REACTOME PARACETAMOL ADME | 26 | 6.01e-01 | 5.92e-02 | 0.979000 |
| REACTOME RHOBTB3 ATPASE CYCLE | 8 | 6.02e-01 | 1.06e-01 | 0.979000 |
| REACTOME VIRAL MESSENGER RNA SYNTHESIS | 44 | 6.02e-01 | 4.54e-02 | 0.979000 |
| REACTOME HIV TRANSCRIPTION ELONGATION | 42 | 6.03e-01 | 4.64e-02 | 0.979000 |
| REACTOME RETINOID CYCLE DISEASE EVENTS | 11 | 6.04e-01 | -9.03e-02 | 0.979000 |
| REACTOME FGFR1B LIGAND BINDING AND ACTIVATION | 6 | 6.05e-01 | 1.22e-01 | 0.979000 |
| REACTOME NECTIN NECL TRANS HETERODIMERIZATION | 7 | 6.05e-01 | -1.13e-01 | 0.979000 |
| REACTOME FLT3 SIGNALING | 38 | 6.09e-01 | -4.79e-02 | 0.979000 |
| REACTOME REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA | 15 | 6.11e-01 | 7.59e-02 | 0.979000 |
| REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR4 | 26 | 6.11e-01 | -5.76e-02 | 0.979000 |
| REACTOME GLUTAMATE AND GLUTAMINE METABOLISM | 13 | 6.12e-01 | -8.13e-02 | 0.979000 |
| REACTOME SIGNALING BY MRAS COMPLEX MUTANTS | 7 | 6.12e-01 | 1.11e-01 | 0.979000 |
| REACTOME EPHRIN SIGNALING | 17 | 6.12e-01 | 7.10e-02 | 0.979000 |
| REACTOME MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS | 13 | 6.13e-01 | -8.11e-02 | 0.979000 |
| REACTOME RUNX3 REGULATES P14 ARF | 10 | 6.14e-01 | 9.22e-02 | 0.979000 |
| REACTOME DUAL INCISION IN TC NER | 63 | 6.15e-01 | 3.67e-02 | 0.979000 |
| REACTOME EGFR INTERACTS WITH PHOSPHOLIPASE C GAMMA | 9 | 6.15e-01 | -9.67e-02 | 0.979000 |
| REACTOME GAP JUNCTION DEGRADATION | 12 | 6.16e-01 | -8.36e-02 | 0.979000 |
| REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION | 32 | 6.19e-01 | 5.08e-02 | 0.979000 |
| REACTOME SIGNALING BY EGFR | 49 | 6.19e-01 | -4.10e-02 | 0.979000 |
| REACTOME PROPIONYL COA CATABOLISM | 5 | 6.21e-01 | 1.28e-01 | 0.979000 |
| REACTOME ONCOGENIC MAPK SIGNALING | 79 | 6.25e-01 | -3.18e-02 | 0.979000 |
| REACTOME PTK6 REGULATES CELL CYCLE | 6 | 6.25e-01 | -1.15e-01 | 0.979000 |
| REACTOME CELLULAR RESPONSE TO HEAT STRESS | 99 | 6.25e-01 | 2.84e-02 | 0.979000 |
| REACTOME SARS COV 2 MODULATES AUTOPHAGY | 11 | 6.26e-01 | -8.49e-02 | 0.979000 |
| REACTOME RNA POLYMERASE II PRE TRANSCRIPTION EVENTS | 77 | 6.26e-01 | 3.21e-02 | 0.979000 |
| REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | 12 | 6.27e-01 | -8.10e-02 | 0.979000 |
| REACTOME ARYL HYDROCARBON RECEPTOR SIGNALLING | 6 | 6.27e-01 | -1.15e-01 | 0.979000 |
| REACTOME TRANS GOLGI NETWORK VESICLE BUDDING | 67 | 6.28e-01 | 3.43e-02 | 0.979000 |
| REACTOME G2 M DNA REPLICATION CHECKPOINT | 5 | 6.28e-01 | -1.25e-01 | 0.979000 |
| REACTOME TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS | 36 | 6.29e-01 | -4.66e-02 | 0.979000 |
| REACTOME CALNEXIN CALRETICULIN CYCLE | 26 | 6.29e-01 | -5.48e-02 | 0.979000 |
| REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | 18 | 6.31e-01 | 6.53e-02 | 0.979000 |
| REACTOME DEADENYLATION OF MRNA | 25 | 6.32e-01 | 5.54e-02 | 0.979000 |
| REACTOME WNT MEDIATED ACTIVATION OF DVL | 8 | 6.32e-01 | -9.77e-02 | 0.979000 |
| REACTOME GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION | 42 | 6.32e-01 | 4.27e-02 | 0.979000 |
| REACTOME REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS | 11 | 6.33e-01 | 8.32e-02 | 0.979000 |
| REACTOME MET INTERACTS WITH TNS PROTEINS | 5 | 6.33e-01 | -1.23e-01 | 0.979000 |
| REACTOME NEUREXINS AND NEUROLIGINS | 51 | 6.33e-01 | -3.86e-02 | 0.979000 |
| REACTOME NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 24 | 6.34e-01 | 5.62e-02 | 0.979000 |
| REACTOME HIV TRANSCRIPTION INITIATION | 43 | 6.34e-01 | 4.19e-02 | 0.979000 |
| REACTOME PLATELET SENSITIZATION BY LDL | 17 | 6.34e-01 | -6.66e-02 | 0.979000 |
| REACTOME GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION | 7 | 6.35e-01 | -1.04e-01 | 0.979000 |
| REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | 19 | 6.35e-01 | 6.29e-02 | 0.979000 |
| REACTOME PHASE 1 INACTIVATION OF FAST NA CHANNELS | 6 | 6.36e-01 | -1.12e-01 | 0.979000 |
| REACTOME PROCESSING AND ACTIVATION OF SUMO | 10 | 6.38e-01 | 8.59e-02 | 0.979000 |
| REACTOME CHOLESTEROL BIOSYNTHESIS | 25 | 6.38e-01 | 5.43e-02 | 0.979000 |
| REACTOME ALPHA OXIDATION OF PHYTANATE | 6 | 6.39e-01 | -1.11e-01 | 0.979000 |
| REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES | 12 | 6.39e-01 | -7.82e-02 | 0.979000 |
| REACTOME FRS MEDIATED FGFR1 SIGNALING | 23 | 6.40e-01 | 5.63e-02 | 0.979000 |
| REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | 19 | 6.40e-01 | 6.19e-02 | 0.979000 |
| REACTOME NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION | 20 | 6.40e-01 | -6.03e-02 | 0.979000 |
| REACTOME HDL CLEARANCE | 5 | 6.41e-01 | -1.21e-01 | 0.979000 |
| REACTOME ANCHORING FIBRIL FORMATION | 13 | 6.41e-01 | -7.46e-02 | 0.979000 |
| REACTOME RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA | 27 | 6.42e-01 | 5.17e-02 | 0.979000 |
| REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC | 198 | 6.42e-01 | 1.92e-02 | 0.979000 |
| REACTOME HATS ACETYLATE HISTONES | 129 | 6.44e-01 | 2.36e-02 | 0.979000 |
| REACTOME DOWNREGULATION OF ERBB4 SIGNALING | 9 | 6.45e-01 | -8.88e-02 | 0.979000 |
| REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | 7 | 6.46e-01 | -1.00e-01 | 0.979000 |
| REACTOME FGFR2B LIGAND BINDING AND ACTIVATION | 10 | 6.47e-01 | 8.37e-02 | 0.979000 |
| REACTOME SIGNALING BY NUCLEAR RECEPTORS | 283 | 6.47e-01 | 1.58e-02 | 0.979000 |
| REACTOME APOPTOTIC EXECUTION PHASE | 49 | 6.47e-01 | 3.78e-02 | 0.979000 |
| REACTOME ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS | 87 | 6.48e-01 | 2.83e-02 | 0.979000 |
| REACTOME REGULATION OF IFNG SIGNALING | 14 | 6.48e-01 | 7.05e-02 | 0.979000 |
| REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION | 59 | 6.48e-01 | -3.43e-02 | 0.979000 |
| REACTOME CLATHRIN MEDIATED ENDOCYTOSIS | 139 | 6.48e-01 | 2.24e-02 | 0.979000 |
| REACTOME G1 S SPECIFIC TRANSCRIPTION | 28 | 6.48e-01 | 4.98e-02 | 0.979000 |
| REACTOME SYNTHESIS OF DOLICHYL PHOSPHATE | 6 | 6.48e-01 | -1.07e-01 | 0.979000 |
| REACTOME NTRK2 ACTIVATES RAC1 | 5 | 6.49e-01 | -1.17e-01 | 0.979000 |
| REACTOME ONCOGENE INDUCED SENESCENCE | 35 | 6.50e-01 | -4.44e-02 | 0.979000 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE | 5 | 6.50e-01 | 1.17e-01 | 0.979000 |
| REACTOME REGULATION OF PTEN MRNA TRANSLATION | 9 | 6.51e-01 | 8.72e-02 | 0.979000 |
| REACTOME N GLYCAN TRIMMING AND ELONGATION IN THE CIS GOLGI | 5 | 6.51e-01 | -1.17e-01 | 0.979000 |
| REACTOME RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX | 29 | 6.52e-01 | -4.84e-02 | 0.979000 |
| REACTOME MITOTIC METAPHASE AND ANAPHASE | 228 | 6.52e-01 | 1.73e-02 | 0.979000 |
| REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION | 35 | 6.53e-01 | -4.39e-02 | 0.979000 |
| REACTOME ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA | 9 | 6.53e-01 | 8.65e-02 | 0.979000 |
| REACTOME SIGNALING BY ERBB2 IN CANCER | 26 | 6.53e-01 | -5.09e-02 | 0.979000 |
| REACTOME REGULATED NECROSIS | 57 | 6.54e-01 | -3.43e-02 | 0.979000 |
| REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS | 8 | 6.54e-01 | 9.15e-02 | 0.979000 |
| REACTOME PASSIVE TRANSPORT BY AQUAPORINS | 13 | 6.55e-01 | -7.16e-02 | 0.979000 |
| REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM | 50 | 6.55e-01 | 3.65e-02 | 0.979000 |
| REACTOME GLYCOGEN SYNTHESIS | 13 | 6.56e-01 | -7.13e-02 | 0.979000 |
| REACTOME BIOTIN TRANSPORT AND METABOLISM | 10 | 6.57e-01 | 8.11e-02 | 0.979000 |
| REACTOME DOWNREGULATION OF ERBB2 SIGNALING | 29 | 6.57e-01 | 4.76e-02 | 0.979000 |
| REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA | 25 | 6.59e-01 | 5.10e-02 | 0.979000 |
| REACTOME PLATELET CALCIUM HOMEOSTASIS | 27 | 6.59e-01 | 4.91e-02 | 0.979000 |
| REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | 16 | 6.60e-01 | 6.34e-02 | 0.979000 |
| REACTOME ER QUALITY CONTROL COMPARTMENT ERQC | 21 | 6.61e-01 | 5.53e-02 | 0.979000 |
| REACTOME EPH EPHRIN SIGNALING | 90 | 6.61e-01 | 2.68e-02 | 0.979000 |
| REACTOME SENSING OF DNA DOUBLE STRAND BREAKS | 6 | 6.61e-01 | -1.03e-01 | 0.979000 |
| REACTOME SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL | 25 | 6.61e-01 | -5.06e-02 | 0.979000 |
| REACTOME TRANSPORT OF ORGANIC ANIONS | 10 | 6.62e-01 | -7.99e-02 | 0.979000 |
| REACTOME REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM | 11 | 6.62e-01 | -7.61e-02 | 0.979000 |
| REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B | 24 | 6.64e-01 | 5.12e-02 | 0.979000 |
| REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | 111 | 6.66e-01 | -2.37e-02 | 0.979000 |
| REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS | 101 | 6.67e-01 | -2.48e-02 | 0.979000 |
| REACTOME ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA | 15 | 6.68e-01 | -6.40e-02 | 0.979000 |
| REACTOME CIPROFLOXACIN ADME | 5 | 6.68e-01 | -1.11e-01 | 0.979000 |
| REACTOME O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS | 38 | 6.68e-01 | 4.01e-02 | 0.979000 |
| REACTOME METABOLISM OF RNA | 675 | 6.69e-01 | -9.66e-03 | 0.979000 |
| REACTOME TRANSPORT OF NUCLEOTIDE SUGARS | 8 | 6.69e-01 | 8.72e-02 | 0.979000 |
| REACTOME RUNX3 REGULATES CDKN1A TRANSCRIPTION | 7 | 6.70e-01 | 9.31e-02 | 0.979000 |
| REACTOME PKA ACTIVATION IN GLUCAGON SIGNALLING | 17 | 6.71e-01 | 5.96e-02 | 0.979000 |
| REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | 35 | 6.71e-01 | 4.15e-02 | 0.979000 |
| REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION | 98 | 6.71e-01 | 2.48e-02 | 0.979000 |
| REACTOME HCMV LATE EVENTS | 110 | 6.72e-01 | 2.34e-02 | 0.979000 |
| REACTOME SIGNALING BY ERBB2 ECD MUTANTS | 16 | 6.72e-01 | -6.12e-02 | 0.979000 |
| REACTOME VLDL CLEARANCE | 6 | 6.72e-01 | -9.98e-02 | 0.979000 |
| REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX | 39 | 6.73e-01 | 3.91e-02 | 0.979000 |
| REACTOME PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING | 5 | 6.73e-01 | 1.09e-01 | 0.979000 |
| REACTOME SIGNALING BY KIT IN DISEASE | 20 | 6.74e-01 | -5.44e-02 | 0.979000 |
| REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | 15 | 6.74e-01 | 6.26e-02 | 0.979000 |
| REACTOME INTERLEUKIN 7 SIGNALING | 31 | 6.76e-01 | -4.33e-02 | 0.979000 |
| REACTOME DNA DAMAGE BYPASS | 47 | 6.77e-01 | 3.51e-02 | 0.979000 |
| REACTOME DISINHIBITION OF SNARE FORMATION | 5 | 6.78e-01 | -1.07e-01 | 0.979000 |
| REACTOME PLASMA LIPOPROTEIN ASSEMBLY | 19 | 6.78e-01 | -5.51e-02 | 0.979000 |
| REACTOME INFECTION WITH MYCOBACTERIUM TUBERCULOSIS | 25 | 6.78e-01 | -4.80e-02 | 0.979000 |
| REACTOME NUCLEOTIDE BIOSYNTHESIS | 14 | 6.78e-01 | 6.41e-02 | 0.979000 |
| REACTOME CHROMOSOME MAINTENANCE | 130 | 6.79e-01 | 2.10e-02 | 0.979000 |
| REACTOME CA2 ACTIVATED K CHANNELS | 9 | 6.80e-01 | -7.94e-02 | 0.979000 |
| REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS | 188 | 6.81e-01 | -1.74e-02 | 0.979000 |
| REACTOME INTERLEUKIN 12 FAMILY SIGNALING | 53 | 6.81e-01 | -3.26e-02 | 0.979000 |
| REACTOME TERMINATION OF TRANSLESION DNA SYNTHESIS | 32 | 6.81e-01 | 4.19e-02 | 0.979000 |
| REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | 22 | 6.82e-01 | 5.05e-02 | 0.979000 |
| REACTOME DEATH RECEPTOR SIGNALING | 143 | 6.82e-01 | 1.99e-02 | 0.979000 |
| REACTOME NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 25 | 6.82e-01 | -4.74e-02 | 0.979000 |
| REACTOME KERATAN SULFATE KERATIN METABOLISM | 34 | 6.82e-01 | -4.06e-02 | 0.979000 |
| REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY | 25 | 6.82e-01 | 4.73e-02 | 0.979000 |
| REACTOME DECTIN 2 FAMILY | 26 | 6.82e-01 | -4.64e-02 | 0.979000 |
| REACTOME RAC1 GTPASE CYCLE | 172 | 6.82e-01 | 1.81e-02 | 0.979000 |
| REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING | 34 | 6.82e-01 | 4.05e-02 | 0.979000 |
| REACTOME SIGNALING BY FLT3 FUSION PROTEINS | 19 | 6.83e-01 | -5.41e-02 | 0.979000 |
| REACTOME COHESIN LOADING ONTO CHROMATIN | 8 | 6.83e-01 | 8.33e-02 | 0.979000 |
| REACTOME RESOLUTION OF SISTER CHROMATID COHESION | 120 | 6.84e-01 | 2.15e-02 | 0.979000 |
| REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION | 10 | 6.84e-01 | 7.43e-02 | 0.979000 |
| REACTOME TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS | 43 | 6.85e-01 | -3.57e-02 | 0.979000 |
| REACTOME HEME DEGRADATION | 15 | 6.85e-01 | -6.04e-02 | 0.979000 |
| REACTOME VASOPRESSIN LIKE RECEPTORS | 5 | 6.86e-01 | -1.05e-01 | 0.979000 |
| REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE | 109 | 6.86e-01 | -2.24e-02 | 0.979000 |
| REACTOME PIWI INTERACTING RNA PIRNA BIOGENESIS | 29 | 6.88e-01 | 4.31e-02 | 0.979000 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES | 43 | 6.89e-01 | 3.52e-02 | 0.979000 |
| REACTOME INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | 28 | 6.89e-01 | 4.36e-02 | 0.979000 |
| REACTOME ZINC TRANSPORTERS | 15 | 6.90e-01 | -5.95e-02 | 0.979000 |
| REACTOME GLYCOSAMINOGLYCAN METABOLISM | 118 | 6.92e-01 | -2.11e-02 | 0.979000 |
| REACTOME POLYMERASE SWITCHING | 13 | 6.93e-01 | 6.33e-02 | 0.979000 |
| REACTOME POST TRANSCRIPTIONAL SILENCING BY SMALL RNAS | 7 | 6.94e-01 | 8.60e-02 | 0.979000 |
| REACTOME COLLAGEN FORMATION | 88 | 6.94e-01 | -2.43e-02 | 0.979000 |
| REACTOME TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE | 39 | 6.94e-01 | 3.64e-02 | 0.979000 |
| REACTOME UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION | 19 | 6.95e-01 | -5.20e-02 | 0.979000 |
| REACTOME TRAF6 MEDIATED NF KB ACTIVATION | 24 | 6.95e-01 | -4.62e-02 | 0.979000 |
| REACTOME TRANSCRIPTION OF THE HIV GENOME | 66 | 6.95e-01 | 2.79e-02 | 0.979000 |
| REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | 13 | 6.96e-01 | -6.27e-02 | 0.979000 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE | 5 | 6.97e-01 | 1.01e-01 | 0.979000 |
| REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | 30 | 6.97e-01 | 4.11e-02 | 0.979000 |
| REACTOME OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS | 8 | 6.98e-01 | 7.93e-02 | 0.979000 |
| REACTOME TLR3 MEDIATED TICAM1 DEPENDENT PROGRAMMED CELL DEATH | 6 | 6.98e-01 | -9.15e-02 | 0.979000 |
| REACTOME ROBO RECEPTORS BIND AKAP5 | 9 | 6.98e-01 | -7.47e-02 | 0.979000 |
| REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM | 78 | 6.98e-01 | -2.54e-02 | 0.979000 |
| REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | 19 | 6.99e-01 | 5.12e-02 | 0.979000 |
| REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | 26 | 7.00e-01 | 4.36e-02 | 0.979000 |
| REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | 10 | 7.02e-01 | -6.99e-02 | 0.979000 |
| REACTOME ELASTIC FIBRE FORMATION | 44 | 7.03e-01 | 3.33e-02 | 0.979000 |
| REACTOME ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES | 59 | 7.03e-01 | -2.87e-02 | 0.979000 |
| REACTOME HYDROLYSIS OF LPC | 9 | 7.03e-01 | 7.33e-02 | 0.979000 |
| REACTOME OXIDATIVE STRESS INDUCED SENESCENCE | 118 | 7.04e-01 | 2.03e-02 | 0.979000 |
| REACTOME TRNA PROCESSING IN THE NUCLEUS | 58 | 7.04e-01 | 2.89e-02 | 0.979000 |
| REACTOME SIALIC ACID METABOLISM | 33 | 7.04e-01 | 3.82e-02 | 0.979000 |
| REACTOME SYNTHESIS OF 12 EICOSATETRAENOIC ACID DERIVATIVES | 7 | 7.07e-01 | 8.21e-02 | 0.979000 |
| REACTOME CROSSLINKING OF COLLAGEN FIBRILS | 16 | 7.07e-01 | 5.42e-02 | 0.979000 |
| REACTOME RHOA GTPASE CYCLE | 142 | 7.08e-01 | 1.82e-02 | 0.979000 |
| REACTOME STRIATED MUSCLE CONTRACTION | 35 | 7.08e-01 | -3.66e-02 | 0.979000 |
| REACTOME GRB2 EVENTS IN ERBB2 SIGNALING | 16 | 7.08e-01 | -5.40e-02 | 0.979000 |
| REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL | 12 | 7.09e-01 | -6.22e-02 | 0.979000 |
| REACTOME RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION | 6 | 7.09e-01 | -8.79e-02 | 0.979000 |
| REACTOME NEF AND SIGNAL TRANSDUCTION | 8 | 7.10e-01 | -7.60e-02 | 0.979000 |
| REACTOME CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION | 11 | 7.11e-01 | 6.46e-02 | 0.979000 |
| REACTOME ATTENUATION PHASE | 27 | 7.11e-01 | 4.12e-02 | 0.979000 |
| REACTOME FORMATION OF INCISION COMPLEX IN GG NER | 40 | 7.11e-01 | -3.38e-02 | 0.979000 |
| REACTOME INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL | 14 | 7.13e-01 | -5.67e-02 | 0.979000 |
| REACTOME STIMULI SENSING CHANNELS | 100 | 7.14e-01 | -2.12e-02 | 0.979000 |
| REACTOME CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS | 100 | 7.14e-01 | 2.12e-02 | 0.979000 |
| REACTOME HDR THROUGH HOMOLOGOUS RECOMBINATION HRR | 66 | 7.15e-01 | 2.60e-02 | 0.979000 |
| REACTOME PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE | 74 | 7.16e-01 | -2.44e-02 | 0.979000 |
| REACTOME RHO GTPASES ACTIVATE FORMINS | 136 | 7.17e-01 | 1.80e-02 | 0.979000 |
| REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION | 26 | 7.17e-01 | 4.10e-02 | 0.979000 |
| REACTOME TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT | 18 | 7.18e-01 | -4.91e-02 | 0.979000 |
| REACTOME UPTAKE AND ACTIONS OF BACTERIAL TOXINS | 28 | 7.20e-01 | -3.92e-02 | 0.979000 |
| REACTOME SUMO IS CONJUGATED TO E1 UBA2 SAE1 | 5 | 7.20e-01 | 9.27e-02 | 0.979000 |
| REACTOME PCP CE PATHWAY | 91 | 7.20e-01 | -2.17e-02 | 0.979000 |
| REACTOME OPSINS | 7 | 7.21e-01 | -7.80e-02 | 0.979000 |
| REACTOME NICOTINATE METABOLISM | 31 | 7.21e-01 | 3.71e-02 | 0.979000 |
| REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR2 | 29 | 7.21e-01 | 3.83e-02 | 0.979000 |
| REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION | 68 | 7.22e-01 | 2.50e-02 | 0.979000 |
| REACTOME HDL ASSEMBLY | 8 | 7.22e-01 | 7.26e-02 | 0.979000 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES | 8 | 7.22e-01 | -7.25e-02 | 0.979000 |
| REACTOME SELECTIVE AUTOPHAGY | 79 | 7.23e-01 | 2.31e-02 | 0.979000 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST | 18 | 7.26e-01 | 4.78e-02 | 0.979000 |
| REACTOME JOSEPHIN DOMAIN DUBS | 11 | 7.27e-01 | -6.08e-02 | 0.979000 |
| REACTOME RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR | 19 | 7.27e-01 | -4.62e-02 | 0.979000 |
| REACTOME G2 M DNA DAMAGE CHECKPOINT | 90 | 7.27e-01 | 2.13e-02 | 0.979000 |
| REACTOME G BETA GAMMA SIGNALLING THROUGH CDC42 | 19 | 7.27e-01 | -4.62e-02 | 0.979000 |
| REACTOME INTERLEUKIN 18 SIGNALING | 8 | 7.28e-01 | 7.11e-02 | 0.979000 |
| REACTOME TNF SIGNALING | 54 | 7.28e-01 | 2.74e-02 | 0.979000 |
| REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE | 69 | 7.29e-01 | -2.41e-02 | 0.979000 |
| REACTOME INSULIN RECEPTOR SIGNALLING CASCADE | 53 | 7.29e-01 | 2.75e-02 | 0.979000 |
| REACTOME REGULATION OF RUNX1 EXPRESSION AND ACTIVITY | 17 | 7.30e-01 | 4.84e-02 | 0.979000 |
| REACTOME SARS COV 1 INFECTION | 136 | 7.30e-01 | -1.72e-02 | 0.979000 |
| REACTOME CONDENSATION OF PROPHASE CHROMOSOMES | 66 | 7.31e-01 | -2.45e-02 | 0.979000 |
| REACTOME REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE | 81 | 7.32e-01 | 2.20e-02 | 0.979000 |
| REACTOME NEDDYLATION | 235 | 7.34e-01 | -1.29e-02 | 0.979000 |
| REACTOME DIGESTION AND ABSORPTION | 22 | 7.34e-01 | -4.18e-02 | 0.979000 |
| REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | 15 | 7.35e-01 | 5.06e-02 | 0.979000 |
| REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | 16 | 7.35e-01 | -4.89e-02 | 0.979000 |
| REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX | 85 | 7.35e-01 | -2.12e-02 | 0.979000 |
| REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE | 63 | 7.36e-01 | -2.46e-02 | 0.979000 |
| REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ | 6 | 7.37e-01 | 7.92e-02 | 0.979000 |
| REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | 24 | 7.37e-01 | 3.96e-02 | 0.979000 |
| REACTOME SIGNALING BY ERBB2 | 50 | 7.37e-01 | -2.74e-02 | 0.979000 |
| REACTOME IRAK1 RECRUITS IKK COMPLEX | 12 | 7.39e-01 | -5.55e-02 | 0.979000 |
| REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | 19 | 7.40e-01 | 4.39e-02 | 0.979000 |
| REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING | 25 | 7.41e-01 | 3.83e-02 | 0.979000 |
| REACTOME SMALL INTERFERING RNA SIRNA BIOGENESIS | 9 | 7.41e-01 | -6.35e-02 | 0.979000 |
| REACTOME BETA CATENIN INDEPENDENT WNT SIGNALING | 145 | 7.42e-01 | 1.59e-02 | 0.979000 |
| REACTOME OTHER INTERLEUKIN SIGNALING | 24 | 7.42e-01 | -3.89e-02 | 0.979000 |
| REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | 14 | 7.42e-01 | -5.09e-02 | 0.979000 |
| REACTOME DUAL INCISION IN GG NER | 39 | 7.43e-01 | 3.04e-02 | 0.979000 |
| REACTOME ESTROGEN BIOSYNTHESIS | 6 | 7.43e-01 | -7.73e-02 | 0.979000 |
| REACTOME INTERLEUKIN 1 PROCESSING | 9 | 7.43e-01 | -6.30e-02 | 0.979000 |
| REACTOME PI3K EVENTS IN ERBB4 SIGNALING | 10 | 7.44e-01 | -5.96e-02 | 0.979000 |
| REACTOME SIGNALING BY CSF1 M CSF IN MYELOID CELLS | 30 | 7.44e-01 | -3.44e-02 | 0.979000 |
| REACTOME PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS | 8 | 7.46e-01 | 6.63e-02 | 0.979000 |
| REACTOME SIGNALING BY NOTCH | 234 | 7.46e-01 | -1.23e-02 | 0.979000 |
| REACTOME MISCELLANEOUS TRANSPORT AND BINDING EVENTS | 24 | 7.48e-01 | -3.79e-02 | 0.979000 |
| REACTOME POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION | 27 | 7.48e-01 | -3.58e-02 | 0.979000 |
| REACTOME GABA B RECEPTOR ACTIVATION | 43 | 7.48e-01 | -2.83e-02 | 0.979000 |
| REACTOME FANCONI ANEMIA PATHWAY | 35 | 7.48e-01 | -3.13e-02 | 0.979000 |
| REACTOME NRCAM INTERACTIONS | 6 | 7.49e-01 | -7.54e-02 | 0.979000 |
| REACTOME CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND | 9 | 7.50e-01 | -6.14e-02 | 0.979000 |
| REACTOMEMATURATION OF SARS COV 1 NUCLEOPROTEIN | 11 | 7.50e-01 | -5.56e-02 | 0.979000 |
| REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1 | 20 | 7.50e-01 | 4.11e-02 | 0.979000 |
| REACTOME INTEGRATION OF PROVIRUS | 9 | 7.50e-01 | -6.12e-02 | 0.979000 |
| REACTOME SIGNALING BY PTK6 | 54 | 7.51e-01 | -2.50e-02 | 0.979000 |
| REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | 37 | 7.51e-01 | -3.02e-02 | 0.979000 |
| REACTOME ERBB2 ACTIVATES PTK6 SIGNALING | 13 | 7.51e-01 | -5.08e-02 | 0.979000 |
| REACTOME RNA POLYMERASE I PROMOTER ESCAPE | 83 | 7.51e-01 | -2.01e-02 | 0.979000 |
| REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION | 31 | 7.51e-01 | -3.29e-02 | 0.979000 |
| REACTOME TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7 | 12 | 7.53e-01 | -5.25e-02 | 0.979000 |
| REACTOME TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY | 16 | 7.53e-01 | 4.54e-02 | 0.979000 |
| REACTOME ACYL CHAIN REMODELLING OF PG | 18 | 7.55e-01 | -4.25e-02 | 0.979000 |
| REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | 63 | 7.55e-01 | -2.27e-02 | 0.979000 |
| REACTOME THYROXINE BIOSYNTHESIS | 10 | 7.55e-01 | 5.69e-02 | 0.979000 |
| REACTOME RAS SIGNALING DOWNSTREAM OF NF1 LOSS OF FUNCTION VARIANTS | 7 | 7.56e-01 | -6.80e-02 | 0.979000 |
| REACTOME NICOTINAMIDE SALVAGING | 19 | 7.56e-01 | 4.12e-02 | 0.979000 |
| REACTOME CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY | 25 | 7.56e-01 | -3.59e-02 | 0.979000 |
| REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | 17 | 7.56e-01 | -4.35e-02 | 0.979000 |
| REACTOME DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS | 14 | 7.57e-01 | 4.78e-02 | 0.979000 |
| REACTOME RNA POLYMERASE II TRANSCRIBES SNRNA GENES | 77 | 7.57e-01 | -2.04e-02 | 0.979000 |
| REACTOME GLUCOSE METABOLISM | 90 | 7.58e-01 | -1.88e-02 | 0.979000 |
| REACTOME MASTL FACILITATES MITOTIC PROGRESSION | 10 | 7.58e-01 | 5.63e-02 | 0.979000 |
| REACTOME CROSS PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS PHAGOSOMES | 6 | 7.58e-01 | -7.26e-02 | 0.979000 |
| REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP | 104 | 7.58e-01 | -1.75e-02 | 0.979000 |
| REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | 15 | 7.59e-01 | 4.57e-02 | 0.979000 |
| REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS | 113 | 7.59e-01 | 1.67e-02 | 0.979000 |
| REACTOME NEGATIVE REGULATION OF MET ACTIVITY | 20 | 7.60e-01 | -3.95e-02 | 0.979000 |
| REACTOME UBIQUINOL BIOSYNTHESIS | 8 | 7.60e-01 | 6.24e-02 | 0.979000 |
| REACTOME VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS | 42 | 7.60e-01 | 2.72e-02 | 0.979000 |
| REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | 101 | 7.60e-01 | 1.76e-02 | 0.979000 |
| REACTOME TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION | 5 | 7.61e-01 | -7.84e-02 | 0.979000 |
| REACTOME CDC42 GTPASE CYCLE | 144 | 7.62e-01 | 1.46e-02 | 0.979000 |
| REACTOME HIV INFECTION | 223 | 7.62e-01 | -1.18e-02 | 0.979000 |
| REACTOME INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS | 37 | 7.62e-01 | -2.88e-02 | 0.979000 |
| REACTOME RHO GTPASE EFFECTORS | 305 | 7.62e-01 | -1.01e-02 | 0.979000 |
| REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS | 34 | 7.63e-01 | 2.99e-02 | 0.979000 |
| REACTOME SUMOYLATION OF SUMOYLATION PROTEINS | 35 | 7.63e-01 | 2.95e-02 | 0.979000 |
| REACTOME GPER1 SIGNALING | 45 | 7.63e-01 | 2.60e-02 | 0.979000 |
| REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION | 74 | 7.64e-01 | 2.02e-02 | 0.980000 |
| REACTOME COLLAGEN CHAIN TRIMERIZATION | 42 | 7.66e-01 | -2.65e-02 | 0.982000 |
| REACTOME NGF INDEPENDANT TRKA ACTIVATION | 5 | 7.68e-01 | 7.62e-02 | 0.982000 |
| REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | 296 | 7.68e-01 | 9.96e-03 | 0.982000 |
| REACTOME ACYL CHAIN REMODELLING OF PE | 29 | 7.69e-01 | 3.15e-02 | 0.982000 |
| REACTOME SIGNALLING TO ERKS | 34 | 7.69e-01 | -2.91e-02 | 0.982000 |
| REACTOME ADHERENS JUNCTIONS INTERACTIONS | 33 | 7.69e-01 | -2.95e-02 | 0.982000 |
| REACTOME DNA REPLICATION INITIATION | 7 | 7.70e-01 | 6.39e-02 | 0.982000 |
| REACTOME PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING | 11 | 7.71e-01 | -5.07e-02 | 0.982000 |
| REACTOME VITAMIN D CALCIFEROL METABOLISM | 12 | 7.71e-01 | 4.84e-02 | 0.982000 |
| REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING | 45 | 7.72e-01 | 2.50e-02 | 0.982000 |
| REACTOME RET SIGNALING | 40 | 7.73e-01 | 2.64e-02 | 0.982000 |
| REACTOME NEPHRIN FAMILY INTERACTIONS | 22 | 7.73e-01 | -3.55e-02 | 0.982000 |
| REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING | 33 | 7.74e-01 | -2.89e-02 | 0.982000 |
| REACTOME REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS | 7 | 7.74e-01 | 6.26e-02 | 0.982000 |
| REACTOME APOPTOTIC FACTOR MEDIATED RESPONSE | 19 | 7.75e-01 | -3.79e-02 | 0.983000 |
| REACTOME REPRESSION OF WNT TARGET GENES | 14 | 7.78e-01 | 4.35e-02 | 0.983000 |
| REACTOME DNA STRAND ELONGATION | 31 | 7.79e-01 | 2.91e-02 | 0.983000 |
| REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | 20 | 7.80e-01 | -3.61e-02 | 0.983000 |
| REACTOME MELANIN BIOSYNTHESIS | 5 | 7.80e-01 | -7.20e-02 | 0.983000 |
| REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION | 138 | 7.83e-01 | 1.36e-02 | 0.983000 |
| REACTOME ACYL CHAIN REMODELLING OF PC | 27 | 7.84e-01 | -3.05e-02 | 0.983000 |
| REACTOME SOS MEDIATED SIGNALLING | 7 | 7.84e-01 | 5.98e-02 | 0.983000 |
| REACTOME SUMOYLATION OF UBIQUITINYLATION PROTEINS | 39 | 7.84e-01 | 2.53e-02 | 0.983000 |
| REACTOME SARS COV 2 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS | 12 | 7.85e-01 | 4.56e-02 | 0.983000 |
| REACTOME G ALPHA 12 13 SIGNALLING EVENTS | 74 | 7.86e-01 | -1.83e-02 | 0.983000 |
| REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS | 15 | 7.87e-01 | -4.04e-02 | 0.983000 |
| REACTOME TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY | 30 | 7.87e-01 | 2.85e-02 | 0.983000 |
| REACTOME MINERALOCORTICOID BIOSYNTHESIS | 6 | 7.87e-01 | -6.37e-02 | 0.983000 |
| REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | 15 | 7.87e-01 | 4.02e-02 | 0.983000 |
| REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE | 52 | 7.88e-01 | -2.15e-02 | 0.983000 |
| REACTOME INTESTINAL ABSORPTION | 5 | 7.89e-01 | 6.92e-02 | 0.983000 |
| REACTOME MRNA SPLICING MINOR PATHWAY | 49 | 7.90e-01 | 2.19e-02 | 0.983000 |
| REACTOME DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE | 30 | 7.91e-01 | -2.79e-02 | 0.983000 |
| REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | 14 | 7.92e-01 | -4.08e-02 | 0.983000 |
| REACTOME ACTIVATION OF SMO | 18 | 7.93e-01 | 3.58e-02 | 0.983000 |
| REACTOME SIGNALING BY WNT | 318 | 7.93e-01 | 8.56e-03 | 0.983000 |
| REACTOME CS DS DEGRADATION | 12 | 7.94e-01 | 4.35e-02 | 0.983000 |
| REACTOME PI 3K CASCADE FGFR1 | 21 | 7.95e-01 | -3.28e-02 | 0.983000 |
| REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS | 18 | 7.95e-01 | 3.53e-02 | 0.983000 |
| REACTOME SUMO IS PROTEOLYTICALLY PROCESSED | 6 | 7.96e-01 | -6.11e-02 | 0.983000 |
| REACTOME NADE MODULATES DEATH SIGNALLING | 5 | 7.97e-01 | 6.64e-02 | 0.983000 |
| REACTOME NEURONAL SYSTEM | 388 | 7.97e-01 | -7.59e-03 | 0.983000 |
| REACTOME SUMOYLATION OF TRANSCRIPTION FACTORS | 20 | 7.98e-01 | -3.30e-02 | 0.983000 |
| REACTOME RHOBTB1 GTPASE CYCLE | 22 | 7.98e-01 | 3.15e-02 | 0.983000 |
| REACTOME UNWINDING OF DNA | 12 | 7.98e-01 | -4.26e-02 | 0.983000 |
| REACTOME SIGNALING BY PDGF | 57 | 7.99e-01 | 1.95e-02 | 0.983000 |
| REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | 30 | 8.01e-01 | -2.66e-02 | 0.983000 |
| REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1 | 31 | 8.01e-01 | -2.61e-02 | 0.983000 |
| REACTOME RUNX3 REGULATES NOTCH SIGNALING | 13 | 8.02e-01 | -4.02e-02 | 0.983000 |
| REACTOME TRANSPORT AND SYNTHESIS OF PAPS | 6 | 8.03e-01 | -5.89e-02 | 0.983000 |
| REACTOME SEPARATION OF SISTER CHROMATIDS | 184 | 8.03e-01 | -1.07e-02 | 0.983000 |
| REACTOME NUCLEAR IMPORT OF REV PROTEIN | 34 | 8.03e-01 | -2.47e-02 | 0.983000 |
| REACTOME XENOBIOTICS | 22 | 8.03e-01 | -3.07e-02 | 0.983000 |
| REACTOME DEFECTS IN BIOTIN BTN METABOLISM | 8 | 8.04e-01 | 5.06e-02 | 0.983000 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3 | 11 | 8.05e-01 | 4.31e-02 | 0.983000 |
| REACTOME FOLDING OF ACTIN BY CCT TRIC | 10 | 8.05e-01 | -4.52e-02 | 0.983000 |
| REACTOME MICRORNA MIRNA BIOGENESIS | 25 | 8.05e-01 | 2.85e-02 | 0.983000 |
| REACTOME FGFR2 LIGAND BINDING AND ACTIVATION | 19 | 8.06e-01 | 3.26e-02 | 0.983000 |
| REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM | 688 | 8.07e-01 | 5.48e-03 | 0.983000 |
| REACTOME PROCESSING OF SMDT1 | 16 | 8.07e-01 | 3.53e-02 | 0.983000 |
| REACTOME SHC MEDIATED CASCADE FGFR1 | 21 | 8.08e-01 | -3.06e-02 | 0.983000 |
| REACTOME HISTIDINE CATABOLISM | 8 | 8.09e-01 | -4.95e-02 | 0.983000 |
| REACTOME DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1 | 9 | 8.09e-01 | -4.66e-02 | 0.983000 |
| REACTOME LEISHMANIA INFECTION | 156 | 8.09e-01 | 1.12e-02 | 0.983000 |
| REACTOME GLYCOGEN METABOLISM | 22 | 8.09e-01 | 2.98e-02 | 0.983000 |
| REACTOME DISEASES OF IMMUNE SYSTEM | 29 | 8.09e-01 | -2.59e-02 | 0.983000 |
| REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX | 15 | 8.09e-01 | 3.60e-02 | 0.983000 |
| REACTOME FRS MEDIATED FGFR3 SIGNALING | 19 | 8.09e-01 | 3.20e-02 | 0.983000 |
| REACTOME FORMATION OF LATERAL PLATE MESODERM | 5 | 8.10e-01 | -6.22e-02 | 0.983000 |
| REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | 89 | 8.11e-01 | 1.46e-02 | 0.983000 |
| REACTOME REGULATION OF SIGNALING BY NODAL | 9 | 8.12e-01 | -4.59e-02 | 0.983000 |
| REACTOME GENE SILENCING BY RNA | 133 | 8.12e-01 | -1.19e-02 | 0.983000 |
| REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR3 | 24 | 8.14e-01 | -2.78e-02 | 0.983000 |
| REACTOME CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2 | 11 | 8.15e-01 | 4.07e-02 | 0.983000 |
| REACTOME BASE EXCISION REPAIR | 87 | 8.16e-01 | 1.44e-02 | 0.983000 |
| REACTOME SYNTHESIS OF PA | 38 | 8.19e-01 | -2.15e-02 | 0.983000 |
| REACTOME CHAPERONE MEDIATED AUTOPHAGY | 20 | 8.19e-01 | 2.96e-02 | 0.983000 |
| REACTOME ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE | 9 | 8.19e-01 | -4.41e-02 | 0.983000 |
| REACTOME REGULATION OF FZD BY UBIQUITINATION | 21 | 8.20e-01 | 2.87e-02 | 0.983000 |
| REACTOME RHOG GTPASE CYCLE | 71 | 8.22e-01 | 1.55e-02 | 0.983000 |
| REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT | 236 | 8.22e-01 | 8.48e-03 | 0.983000 |
| REACTOME INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE | 20 | 8.23e-01 | 2.89e-02 | 0.983000 |
| REACTOME SIGNALING BY ALK IN CANCER | 53 | 8.23e-01 | -1.77e-02 | 0.983000 |
| REACTOME METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES | 33 | 8.24e-01 | -2.23e-02 | 0.983000 |
| REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES | 21 | 8.25e-01 | -2.78e-02 | 0.983000 |
| REACTOME DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE | 76 | 8.26e-01 | 1.46e-02 | 0.983000 |
| REACTOME MATURATION OF SARS COV 1 SPIKE PROTEIN | 5 | 8.26e-01 | -5.66e-02 | 0.983000 |
| REACTOME TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE | 20 | 8.26e-01 | 2.83e-02 | 0.983000 |
| REACTOME ACYL CHAIN REMODELING OF CL | 5 | 8.28e-01 | 5.63e-02 | 0.983000 |
| REACTOME SUPPRESSION OF PHAGOSOMAL MATURATION | 13 | 8.28e-01 | -3.49e-02 | 0.983000 |
| REACTOME INFECTIOUS DISEASE | 910 | 8.28e-01 | -4.24e-03 | 0.983000 |
| REACTOME PTK6 EXPRESSION | 5 | 8.28e-01 | 5.60e-02 | 0.983000 |
| REACTOME GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER | 25 | 8.29e-01 | -2.50e-02 | 0.983000 |
| REACTOME PREDNISONE ADME | 10 | 8.29e-01 | -3.94e-02 | 0.983000 |
| REACTOME BICARBONATE TRANSPORTERS | 10 | 8.29e-01 | 3.94e-02 | 0.983000 |
| REACTOME THE ACTIVATION OF ARYLSULFATASES | 8 | 8.30e-01 | -4.39e-02 | 0.983000 |
| REACTOME MOLYBDENUM COFACTOR BIOSYNTHESIS | 6 | 8.30e-01 | 5.06e-02 | 0.983000 |
| REACTOME FCGR3A MEDIATED IL10 SYNTHESIS | 36 | 8.30e-01 | -2.07e-02 | 0.983000 |
| REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS | 5 | 8.31e-01 | 5.51e-02 | 0.983000 |
| REACTOME SIGNAL AMPLIFICATION | 33 | 8.32e-01 | -2.13e-02 | 0.983000 |
| REACTOME SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA PHE | 6 | 8.33e-01 | -4.96e-02 | 0.983000 |
| REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | 20 | 8.33e-01 | -2.72e-02 | 0.983000 |
| REACTOME SIGNALING BY FGFR2 IIIA TM | 19 | 8.34e-01 | -2.77e-02 | 0.983000 |
| REACTOME ADRENOCEPTORS | 9 | 8.35e-01 | -4.01e-02 | 0.983000 |
| REACTOME RNA POLYMERASE III TRANSCRIPTION TERMINATION | 23 | 8.35e-01 | -2.50e-02 | 0.983000 |
| REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS | 418 | 8.36e-01 | 5.91e-03 | 0.983000 |
| REACTOME VLDLR INTERNALISATION AND DEGRADATION | 16 | 8.37e-01 | -2.98e-02 | 0.983000 |
| REACTOME COENZYME A BIOSYNTHESIS | 8 | 8.37e-01 | 4.21e-02 | 0.983000 |
| REACTOME P75NTR SIGNALS VIA NF KB | 15 | 8.38e-01 | -3.04e-02 | 0.983000 |
| REACTOME ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING | 9 | 8.39e-01 | 3.91e-02 | 0.983000 |
| REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | 11 | 8.40e-01 | -3.52e-02 | 0.983000 |
| REACTOME FORMATION OF APOPTOSOME | 10 | 8.40e-01 | -3.69e-02 | 0.983000 |
| REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING | 29 | 8.40e-01 | 2.16e-02 | 0.983000 |
| REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | 8 | 8.41e-01 | -4.11e-02 | 0.983000 |
| REACTOME ENOS ACTIVATION | 11 | 8.41e-01 | -3.49e-02 | 0.983000 |
| REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | 51 | 8.42e-01 | 1.61e-02 | 0.983000 |
| REACTOME SHC RELATED EVENTS TRIGGERED BY IGF1R | 9 | 8.42e-01 | -3.83e-02 | 0.983000 |
| REACTOME RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES TREGS | 9 | 8.43e-01 | -3.82e-02 | 0.983000 |
| REACTOME HCMV EARLY EVENTS | 128 | 8.44e-01 | 1.01e-02 | 0.983000 |
| REACTOME O LINKED GLYCOSYLATION | 109 | 8.44e-01 | 1.09e-02 | 0.983000 |
| REACTOME GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION | 30 | 8.44e-01 | -2.07e-02 | 0.983000 |
| REACTOME SPHINGOLIPID METABOLISM | 84 | 8.45e-01 | -1.23e-02 | 0.983000 |
| REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES | 255 | 8.45e-01 | -7.10e-03 | 0.983000 |
| REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS | 16 | 8.45e-01 | 2.82e-02 | 0.983000 |
| REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | 14 | 8.45e-01 | -3.01e-02 | 0.983000 |
| REACTOME METAL ION SLC TRANSPORTERS | 23 | 8.46e-01 | 2.35e-02 | 0.983000 |
| REACTOME ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN | 13 | 8.47e-01 | -3.09e-02 | 0.983000 |
| REACTOME RA BIOSYNTHESIS PATHWAY | 22 | 8.47e-01 | -2.37e-02 | 0.983000 |
| REACTOME SYNTHESIS OF 5 EICOSATETRAENOIC ACIDS | 9 | 8.49e-01 | -3.66e-02 | 0.983000 |
| REACTOME SNRNP ASSEMBLY | 53 | 8.49e-01 | -1.51e-02 | 0.983000 |
| REACTOME ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS | 10 | 8.50e-01 | 3.45e-02 | 0.983000 |
| REACTOME LYSINE CATABOLISM | 12 | 8.51e-01 | -3.14e-02 | 0.983000 |
| REACTOME G2 PHASE | 5 | 8.51e-01 | 4.85e-02 | 0.983000 |
| REACTOME REGULATION OF TP53 ACTIVITY THROUGH METHYLATION | 19 | 8.52e-01 | -2.47e-02 | 0.983000 |
| REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4 | 33 | 8.53e-01 | -1.87e-02 | 0.983000 |
| REACTOME HEME BIOSYNTHESIS | 13 | 8.53e-01 | 2.97e-02 | 0.983000 |
| REACTOME NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION | 193 | 8.53e-01 | 7.74e-03 | 0.983000 |
| REACTOME ION CHANNEL TRANSPORT | 172 | 8.53e-01 | 8.20e-03 | 0.983000 |
| REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION | 20 | 8.53e-01 | 2.39e-02 | 0.983000 |
| REACTOME HYALURONAN METABOLISM | 17 | 8.53e-01 | 2.59e-02 | 0.983000 |
| REACTOME REGULATED PROTEOLYSIS OF P75NTR | 11 | 8.54e-01 | -3.19e-02 | 0.983000 |
| REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS | 5 | 8.55e-01 | -4.73e-02 | 0.983000 |
| REACTOME PEROXISOMAL LIPID METABOLISM | 28 | 8.55e-01 | 1.99e-02 | 0.983000 |
| REACTOME GABA RECEPTOR ACTIVATION | 57 | 8.55e-01 | -1.40e-02 | 0.983000 |
| REACTOME PLATELET HOMEOSTASIS | 85 | 8.56e-01 | -1.14e-02 | 0.983000 |
| REACTOME PI3K AKT SIGNALING IN CANCER | 103 | 8.56e-01 | -1.04e-02 | 0.983000 |
| REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | 17 | 8.56e-01 | -2.54e-02 | 0.983000 |
| REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | 20 | 8.57e-01 | 2.33e-02 | 0.983000 |
| REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION | 62 | 8.58e-01 | -1.32e-02 | 0.983000 |
| REACTOME METABOLISM OF COFACTORS | 19 | 8.58e-01 | -2.37e-02 | 0.983000 |
| REACTOME ABACAVIR ADME | 9 | 8.61e-01 | -3.38e-02 | 0.983000 |
| REACTOME ERK MAPK TARGETS | 20 | 8.61e-01 | 2.26e-02 | 0.983000 |
| REACTOME SIGNALING BY MST1 | 5 | 8.61e-01 | 4.52e-02 | 0.983000 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING | 6 | 8.62e-01 | -4.11e-02 | 0.983000 |
| REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS | 14 | 8.62e-01 | -2.68e-02 | 0.983000 |
| REACTOME RHOBTB GTPASE CYCLE | 34 | 8.64e-01 | 1.70e-02 | 0.983000 |
| REACTOME DEFECTIVE GALNT3 CAUSES HFTC | 16 | 8.64e-01 | 2.47e-02 | 0.983000 |
| REACTOME ETHANOL OXIDATION | 12 | 8.67e-01 | 2.79e-02 | 0.983000 |
| REACTOME METABOLISM OF PORPHYRINS | 26 | 8.67e-01 | 1.89e-02 | 0.983000 |
| REACTOME ERBB2 REGULATES CELL MOTILITY | 15 | 8.70e-01 | -2.45e-02 | 0.983000 |
| REACTOME DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A | 5 | 8.70e-01 | 4.24e-02 | 0.983000 |
| REACTOME VEGFR2 MEDIATED CELL PROLIFERATION | 19 | 8.70e-01 | 2.17e-02 | 0.983000 |
| REACTOME PECAM1 INTERACTIONS | 12 | 8.70e-01 | -2.72e-02 | 0.983000 |
| REACTOME INLA MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS | 9 | 8.70e-01 | -3.14e-02 | 0.983000 |
| REACTOME RHOBTB2 GTPASE CYCLE | 22 | 8.71e-01 | -2.01e-02 | 0.983000 |
| REACTOME UNFOLDED PROTEIN RESPONSE UPR | 88 | 8.73e-01 | -9.88e-03 | 0.983000 |
| REACTOME PRE NOTCH EXPRESSION AND PROCESSING | 112 | 8.73e-01 | 8.72e-03 | 0.983000 |
| REACTOME SIGNALING BY FGFR1 IN DISEASE | 38 | 8.73e-01 | -1.49e-02 | 0.983000 |
| REACTOME ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS | 41 | 8.74e-01 | 1.43e-02 | 0.983000 |
| REACTOME REGULATION OF INSULIN SECRETION | 77 | 8.74e-01 | 1.05e-02 | 0.983000 |
| REACTOME FATTY ACIDS | 15 | 8.74e-01 | -2.36e-02 | 0.983000 |
| REACTOME AQUAPORIN MEDIATED TRANSPORT | 51 | 8.74e-01 | -1.28e-02 | 0.983000 |
| REACTOME EARLY PHASE OF HIV LIFE CYCLE | 14 | 8.75e-01 | -2.43e-02 | 0.983000 |
| REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES | 37 | 8.75e-01 | 1.49e-02 | 0.983000 |
| REACTOME HYALURONAN UPTAKE AND DEGRADATION | 12 | 8.76e-01 | 2.59e-02 | 0.983000 |
| REACTOME ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS | 11 | 8.78e-01 | -2.68e-02 | 0.983000 |
| REACTOME INACTIVATION OF CDC42 AND RAC1 | 8 | 8.78e-01 | -3.14e-02 | 0.983000 |
| REACTOME CYTOCHROME C MEDIATED APOPTOTIC RESPONSE | 12 | 8.79e-01 | -2.55e-02 | 0.983000 |
| REACTOME DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS | 25 | 8.79e-01 | -1.76e-02 | 0.983000 |
| REACTOME SEMA3A PAK DEPENDENT AXON REPULSION | 14 | 8.80e-01 | -2.33e-02 | 0.983000 |
| REACTOME UPTAKE OF DIETARY COBALAMINS INTO ENTEROCYTES | 9 | 8.80e-01 | 2.91e-02 | 0.983000 |
| REACTOME METALLOPROTEASE DUBS | 36 | 8.81e-01 | 1.44e-02 | 0.983000 |
| REACTOME CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND | 16 | 8.81e-01 | -2.15e-02 | 0.983000 |
| REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | 16 | 8.82e-01 | -2.15e-02 | 0.983000 |
| REACTOME HDR THROUGH MMEJ ALT NHEJ | 12 | 8.82e-01 | -2.47e-02 | 0.983000 |
| REACTOME PI 3K CASCADE FGFR2 | 22 | 8.82e-01 | 1.82e-02 | 0.983000 |
| REACTOME RHO GTPASES ACTIVATE CIT | 19 | 8.82e-01 | -1.96e-02 | 0.983000 |
| REACTOME NRAGE SIGNALS DEATH THROUGH JNK | 53 | 8.83e-01 | -1.17e-02 | 0.983000 |
| REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | 10 | 8.84e-01 | -2.67e-02 | 0.983000 |
| REACTOME UB SPECIFIC PROCESSING PROTEASES | 187 | 8.84e-01 | -6.17e-03 | 0.983000 |
| REACTOME DEGRADATION OF CYSTEINE AND HOMOCYSTEINE | 15 | 8.85e-01 | -2.16e-02 | 0.983000 |
| REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12 | 22 | 8.85e-01 | 1.78e-02 | 0.983000 |
| REACTOME RESPONSE OF MTB TO PHAGOCYTOSIS | 22 | 8.86e-01 | -1.77e-02 | 0.983000 |
| REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION | 32 | 8.86e-01 | 1.46e-02 | 0.983000 |
| REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE | 37 | 8.87e-01 | -1.34e-02 | 0.983000 |
| REACTOME NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY | 6 | 8.88e-01 | 3.32e-02 | 0.983000 |
| REACTOME CD163 MEDIATING AN ANTI INFLAMMATORY RESPONSE | 9 | 8.88e-01 | -2.71e-02 | 0.983000 |
| REACTOME DAG AND IP3 SIGNALING | 40 | 8.89e-01 | 1.28e-02 | 0.983000 |
| REACTOME PEPTIDE LIGAND BINDING RECEPTORS | 188 | 8.90e-01 | 5.86e-03 | 0.983000 |
| REACTOME GENERATION OF SECOND MESSENGER MOLECULES | 30 | 8.91e-01 | 1.44e-02 | 0.983000 |
| REACTOME MEIOTIC SYNAPSIS | 73 | 8.91e-01 | -9.24e-03 | 0.983000 |
| REACTOME RRNA PROCESSING IN THE MITOCHONDRION | 9 | 8.92e-01 | 2.62e-02 | 0.983000 |
| REACTOME CA DEPENDENT EVENTS | 36 | 8.92e-01 | -1.31e-02 | 0.983000 |
| REACTOME PI3K AKT ACTIVATION | 9 | 8.93e-01 | -2.59e-02 | 0.983000 |
| REACTOME FGFR3 LIGAND BINDING AND ACTIVATION | 12 | 8.93e-01 | -2.25e-02 | 0.983000 |
| REACTOME DNA DAMAGE REVERSAL | 8 | 8.93e-01 | 2.75e-02 | 0.983000 |
| REACTOME MATURATION OF SARS COV 2 SPIKE PROTEIN | 35 | 8.95e-01 | 1.29e-02 | 0.983000 |
| REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN | 32 | 8.95e-01 | -1.34e-02 | 0.983000 |
| REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | 13 | 8.96e-01 | -2.09e-02 | 0.983000 |
| REACTOME PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS | 21 | 8.97e-01 | 1.63e-02 | 0.983000 |
| REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | 9 | 8.97e-01 | 2.49e-02 | 0.983000 |
| REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | 32 | 8.98e-01 | 1.31e-02 | 0.983000 |
| REACTOME SIGNALING BY FGFR2 IN DISEASE | 42 | 8.99e-01 | 1.13e-02 | 0.983000 |
| REACTOME METABOLISM OF STEROID HORMONES | 35 | 9.00e-01 | 1.23e-02 | 0.983000 |
| REACTOME MATURATION OF SARS COV 2 NUCLEOPROTEIN | 15 | 9.00e-01 | 1.88e-02 | 0.983000 |
| REACTOME BETA CATENIN PHOSPHORYLATION CASCADE | 16 | 9.00e-01 | 1.82e-02 | 0.983000 |
| REACTOME SULFIDE OXIDATION TO SULFATE | 6 | 9.01e-01 | 2.93e-02 | 0.983000 |
| REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS | 53 | 9.02e-01 | 9.78e-03 | 0.983000 |
| REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | 13 | 9.03e-01 | 1.96e-02 | 0.983000 |
| REACTOME SEROTONIN RECEPTORS | 11 | 9.03e-01 | 2.13e-02 | 0.983000 |
| REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | 29 | 9.04e-01 | -1.30e-02 | 0.983000 |
| REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT | 159 | 9.04e-01 | -5.56e-03 | 0.983000 |
| REACTOME TYPE I HEMIDESMOSOME ASSEMBLY | 11 | 9.05e-01 | -2.08e-02 | 0.983000 |
| REACTOME CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN | 45 | 9.06e-01 | 1.02e-02 | 0.983000 |
| REACTOME RHO GTPASES ACTIVATE PAKS | 19 | 9.06e-01 | -1.57e-02 | 0.983000 |
| REACTOME LAMININ INTERACTIONS | 28 | 9.06e-01 | 1.29e-02 | 0.983000 |
| REACTOME HDR THROUGH SINGLE STRAND ANNEALING SSA | 37 | 9.07e-01 | 1.11e-02 | 0.983000 |
| REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | 10 | 9.08e-01 | 2.11e-02 | 0.983000 |
| REACTOME KETONE BODY METABOLISM | 9 | 9.08e-01 | 2.22e-02 | 0.983000 |
| REACTOME TRANSLESION SYNTHESIS BY POLK | 17 | 9.09e-01 | -1.61e-02 | 0.983000 |
| REACTOME SUPPRESSION OF APOPTOSIS | 7 | 9.10e-01 | 2.48e-02 | 0.983000 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE | 20 | 9.10e-01 | 1.46e-02 | 0.983000 |
| REACTOME INDUCTION OF CELL CELL FUSION | 12 | 9.11e-01 | 1.86e-02 | 0.983000 |
| REACTOME ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA | 5 | 9.11e-01 | 2.87e-02 | 0.983000 |
| REACTOME EGFR DOWNREGULATION | 30 | 9.12e-01 | 1.17e-02 | 0.983000 |
| REACTOME AMINO ACID CONJUGATION | 9 | 9.12e-01 | 2.13e-02 | 0.983000 |
| REACTOME INTERLEUKIN 23 SIGNALING | 9 | 9.13e-01 | 2.11e-02 | 0.983000 |
| REACTOME HSF1 ACTIVATION | 29 | 9.13e-01 | -1.17e-02 | 0.983000 |
| REACTOME TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS | 55 | 9.13e-01 | -8.50e-03 | 0.983000 |
| REACTOME COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES | 65 | 9.13e-01 | -7.81e-03 | 0.983000 |
| REACTOME PP2A MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS | 6 | 9.13e-01 | 2.57e-02 | 0.983000 |
| REACTOME LIPID PARTICLE ORGANIZATION | 6 | 9.14e-01 | 2.56e-02 | 0.983000 |
| REACTOME BIOLOGICAL OXIDATIONS | 210 | 9.14e-01 | -4.34e-03 | 0.983000 |
| REACTOME CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION | 24 | 9.14e-01 | 1.27e-02 | 0.983000 |
| REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | 23 | 9.14e-01 | 1.30e-02 | 0.983000 |
| REACTOME ACYL CHAIN REMODELLING OF PS | 22 | 9.14e-01 | -1.32e-02 | 0.983000 |
| REACTOME CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY | 12 | 9.16e-01 | 1.76e-02 | 0.983000 |
| REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | 16 | 9.16e-01 | -1.52e-02 | 0.983000 |
| REACTOME PROCESSING OF INTRONLESS PRE MRNAS | 19 | 9.17e-01 | -1.38e-02 | 0.983000 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING | 5 | 9.17e-01 | 2.69e-02 | 0.983000 |
| REACTOME CITRIC ACID CYCLE TCA CYCLE | 21 | 9.17e-01 | 1.31e-02 | 0.983000 |
| REACTOME RESPONSE TO METAL IONS | 14 | 9.18e-01 | -1.59e-02 | 0.983000 |
| REACTOME SYNTHESIS OF KETONE BODIES | 8 | 9.19e-01 | -2.08e-02 | 0.983000 |
| REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION | 89 | 9.19e-01 | -6.25e-03 | 0.983000 |
| REACTOME PHOSPHOLIPID METABOLISM | 201 | 9.19e-01 | 4.16e-03 | 0.983000 |
| REACTOME SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER | 15 | 9.20e-01 | -1.50e-02 | 0.983000 |
| REACTOME HYALURONAN BIOSYNTHESIS AND EXPORT | 5 | 9.20e-01 | 2.59e-02 | 0.983000 |
| REACTOME ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY | 10 | 9.21e-01 | 1.81e-02 | 0.983000 |
| REACTOME COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING | 32 | 9.25e-01 | -9.57e-03 | 0.986000 |
| REACTOME VITAMIN B1 THIAMIN METABOLISM | 5 | 9.26e-01 | 2.40e-02 | 0.986000 |
| REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R | 52 | 9.27e-01 | 7.39e-03 | 0.986000 |
| REACTOME SIGNALING BY NOTCH3 | 48 | 9.27e-01 | 7.62e-03 | 0.986000 |
| REACTOME INTERLEUKIN 12 SIGNALING | 43 | 9.28e-01 | -8.01e-03 | 0.986000 |
| REACTOME MITOCHONDRIAL UNCOUPLING | 5 | 9.29e-01 | 2.30e-02 | 0.986000 |
| REACTOME RHOH GTPASE CYCLE | 37 | 9.31e-01 | -8.23e-03 | 0.986000 |
| REACTOME MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION | 15 | 9.31e-01 | -1.29e-02 | 0.986000 |
| REACTOME CYP2E1 REACTIONS | 10 | 9.31e-01 | -1.57e-02 | 0.986000 |
| REACTOME PYROPTOSIS | 27 | 9.32e-01 | 9.47e-03 | 0.986000 |
| REACTOME FGFR3B LIGAND BINDING AND ACTIVATION | 7 | 9.33e-01 | -1.84e-02 | 0.986000 |
| REACTOME FRS MEDIATED FGFR4 SIGNALING | 21 | 9.33e-01 | -1.06e-02 | 0.986000 |
| REACTOME SIGNALING BY NTRKS | 132 | 9.33e-01 | -4.23e-03 | 0.986000 |
| REACTOME PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR | 21 | 9.33e-01 | -1.06e-02 | 0.986000 |
| REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS | 21 | 9.33e-01 | -1.06e-02 | 0.986000 |
| REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2 | 13 | 9.34e-01 | 1.32e-02 | 0.986000 |
| REACTOME MATURATION OF PROTEIN 3A | 9 | 9.35e-01 | -1.57e-02 | 0.986000 |
| REACTOME ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS | 27 | 9.35e-01 | 9.03e-03 | 0.986000 |
| REACTOME REACTIONS SPECIFIC TO THE COMPLEX N GLYCAN SYNTHESIS PATHWAY | 10 | 9.35e-01 | 1.48e-02 | 0.986000 |
| REACTOME MITOTIC PROPHASE | 134 | 9.36e-01 | 4.03e-03 | 0.986000 |
| REACTOME CHOLINE CATABOLISM | 6 | 9.37e-01 | 1.85e-02 | 0.987000 |
| REACTOME PENTOSE PHOSPHATE PATHWAY | 12 | 9.38e-01 | 1.30e-02 | 0.987000 |
| REACTOME GLYCEROPHOSPHOLIPID CATABOLISM | 7 | 9.39e-01 | 1.67e-02 | 0.987000 |
| REACTOME PERK REGULATES GENE EXPRESSION | 31 | 9.39e-01 | -7.89e-03 | 0.987000 |
| REACTOME NUCLEAR ENVELOPE BREAKDOWN | 52 | 9.40e-01 | 6.08e-03 | 0.987000 |
| REACTOME RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES | 16 | 9.42e-01 | -1.06e-02 | 0.988000 |
| REACTOME PROTEIN FOLDING | 96 | 9.42e-01 | -4.29e-03 | 0.988000 |
| REACTOME FGFR1 LIGAND BINDING AND ACTIVATION | 15 | 9.42e-01 | 1.08e-02 | 0.988000 |
| REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | 76 | 9.45e-01 | 4.54e-03 | 0.990000 |
| REACTOME DEPOLYMERISATION OF THE NUCLEAR LAMINA | 14 | 9.46e-01 | 1.05e-02 | 0.990000 |
| REACTOME CELL CYCLE CHECKPOINTS | 284 | 9.47e-01 | -2.31e-03 | 0.991000 |
| REACTOME INTRAFLAGELLAR TRANSPORT | 50 | 9.48e-01 | 5.34e-03 | 0.991000 |
| REACTOME CRISTAE FORMATION | 27 | 9.48e-01 | 7.18e-03 | 0.991000 |
| REACTOME KSRP KHSRP BINDS AND DESTABILIZES MRNA | 17 | 9.50e-01 | 8.76e-03 | 0.992000 |
| REACTOME IRS MEDIATED SIGNALLING | 47 | 9.50e-01 | 5.26e-03 | 0.992000 |
| REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION | 100 | 9.51e-01 | -3.54e-03 | 0.992000 |
| REACTOME SIGNALING BY NOTCH1 T 7 9 NOTCH1 M1580 K2555 TRANSLOCATION MUTANT | 7 | 9.52e-01 | 1.32e-02 | 0.992000 |
| REACTOME METABOLISM OF CARBOHYDRATES | 279 | 9.54e-01 | -2.01e-03 | 0.994000 |
| REACTOME METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION | 15 | 9.55e-01 | 8.45e-03 | 0.994000 |
| REACTOME RNA POLYMERASE III CHAIN ELONGATION | 18 | 9.57e-01 | 7.41e-03 | 0.995000 |
| REACTOME INTRA GOLGI TRAFFIC | 43 | 9.57e-01 | -4.75e-03 | 0.995000 |
| REACTOME RAP1 SIGNALLING | 16 | 9.58e-01 | 7.61e-03 | 0.995000 |
| REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | 15 | 9.59e-01 | -7.74e-03 | 0.995000 |
| REACTOME PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1 | 9 | 9.59e-01 | 9.94e-03 | 0.995000 |
| REACTOME LATE SARS COV 2 INFECTION EVENTS | 67 | 9.59e-01 | -3.63e-03 | 0.995000 |
| REACTOME FBXW7 MUTANTS AND NOTCH1 IN CANCER | 5 | 9.61e-01 | 1.26e-02 | 0.996000 |
| REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | 11 | 9.62e-01 | 8.19e-03 | 0.996000 |
| REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION | 26 | 9.63e-01 | -5.27e-03 | 0.996000 |
| REACTOME ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS | 17 | 9.63e-01 | -6.43e-03 | 0.996000 |
| REACTOME PLASMA LIPOPROTEIN REMODELING | 33 | 9.64e-01 | -4.59e-03 | 0.996000 |
| REACTOME MITOCHONDRIAL CALCIUM ION TRANSPORT | 23 | 9.65e-01 | -5.28e-03 | 0.997000 |
| REACTOME TOXICITY OF BOTULINUM TOXIN TYPE D BOTD | 5 | 9.65e-01 | -1.13e-02 | 0.997000 |
| REACTOME AZATHIOPRINE ADME | 22 | 9.67e-01 | 5.12e-03 | 0.998000 |
| REACTOME RELEASE OF HH NP FROM THE SECRETING CELL | 8 | 9.68e-01 | 8.22e-03 | 0.998000 |
| REACTOME ARACHIDONIC ACID METABOLISM | 57 | 9.69e-01 | 2.94e-03 | 0.998000 |
| REACTOME SLC TRANSPORTER DISORDERS | 94 | 9.70e-01 | 2.27e-03 | 0.998000 |
| REACTOME MITOTIC TELOPHASE CYTOKINESIS | 11 | 9.71e-01 | 6.33e-03 | 0.998000 |
| REACTOME RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS | 5 | 9.72e-01 | -9.22e-03 | 0.998000 |
| REACTOME LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS | 19 | 9.72e-01 | 4.70e-03 | 0.998000 |
| REACTOME SYNTHESIS OF UDP N ACETYL GLUCOSAMINE | 7 | 9.72e-01 | 7.53e-03 | 0.998000 |
| REACTOME POLO LIKE KINASE MEDIATED EVENTS | 16 | 9.73e-01 | 4.92e-03 | 0.998000 |
| REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE | 35 | 9.73e-01 | 3.27e-03 | 0.998000 |
| REACTOME ACTIVATION OF TRKA RECEPTORS | 6 | 9.74e-01 | 7.82e-03 | 0.998000 |
| REACTOME REGULATION OF GENE EXPRESSION IN ENDOCRINE COMMITTED NEUROG3 PROGENITOR CELLS | 5 | 9.74e-01 | -8.34e-03 | 0.999000 |
| REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL | 15 | 9.75e-01 | 4.63e-03 | 0.999000 |
| REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR | 24 | 9.76e-01 | -3.57e-03 | 0.999000 |
| REACTOME SYNTHESIS OF DIPHTHAMIDE EEF2 | 8 | 9.76e-01 | 6.09e-03 | 0.999000 |
| REACTOME CONJUGATION OF BENZOATE WITH GLYCINE | 6 | 9.78e-01 | 6.53e-03 | 0.999000 |
| REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | 16 | 9.78e-01 | 3.97e-03 | 0.999000 |
| REACTOME REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS | 15 | 9.79e-01 | -3.99e-03 | 0.999000 |
| REACTOME TRAIL SIGNALING | 8 | 9.79e-01 | 5.28e-03 | 0.999000 |
| REACTOME KERATAN SULFATE DEGRADATION | 13 | 9.80e-01 | 4.05e-03 | 0.999000 |
| REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS | 29 | 9.81e-01 | -2.60e-03 | 0.999000 |
| REACTOME GERM LAYER FORMATION AT GASTRULATION | 17 | 9.81e-01 | -3.38e-03 | 0.999000 |
| REACTOME HDACS DEACETYLATE HISTONES | 85 | 9.82e-01 | 1.39e-03 | 0.999000 |
| REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION | 23 | 9.83e-01 | 2.52e-03 | 0.999000 |
| REACTOME THE NLRP3 INFLAMMASOME | 16 | 9.84e-01 | 2.86e-03 | 0.999000 |
| REACTOME TAK1 DEPENDENT IKK AND NF KAPPA B ACTIVATION | 41 | 9.85e-01 | 1.69e-03 | 0.999000 |
| REACTOME PD 1 SIGNALING | 21 | 9.86e-01 | 2.28e-03 | 0.999000 |
| REACTOME BETA DEFENSINS | 27 | 9.86e-01 | 2.01e-03 | 0.999000 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN | 13 | 9.86e-01 | 2.82e-03 | 0.999000 |
| REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS | 35 | 9.86e-01 | -1.70e-03 | 0.999000 |
| REACTOME NUCLEAR PORE COMPLEX NPC DISASSEMBLY | 36 | 9.86e-01 | -1.63e-03 | 0.999000 |
| REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | 38 | 9.87e-01 | -1.56e-03 | 0.999000 |
| REACTOME PHYSIOLOGICAL FACTORS | 14 | 9.88e-01 | -2.32e-03 | 1.000000 |
| REACTOME BASE EXCISION REPAIR AP SITE FORMATION | 59 | 9.90e-01 | -9.71e-04 | 1.000000 |
| REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | 23 | 9.91e-01 | 1.42e-03 | 1.000000 |
| REACTOME COMPLEX I BIOGENESIS | 49 | 9.91e-01 | 9.55e-04 | 1.000000 |
| REACTOME DEX H BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION | 7 | 9.92e-01 | -2.12e-03 | 1.000000 |
| REACTOME SIGNALING BY RECEPTOR TYROSINE KINASES | 507 | 9.92e-01 | 2.49e-04 | 1.000000 |
| REACTOME REGULATION OF NPAS4 GENE EXPRESSION | 13 | 9.92e-01 | -1.52e-03 | 1.000000 |
| REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | 17 | 9.93e-01 | 1.27e-03 | 1.000000 |
| REACTOME DEFECTIVE LFNG CAUSES SCDO3 | 5 | 9.93e-01 | 2.27e-03 | 1.000000 |
| REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | 28 | 9.94e-01 | -7.70e-04 | 1.000000 |
| REACTOME RECEPTOR MEDIATED MITOPHAGY | 10 | 9.95e-01 | -1.19e-03 | 1.000000 |
| REACTOME SODIUM CALCIUM EXCHANGERS | 11 | 9.95e-01 | -1.12e-03 | 1.000000 |
| REACTOME ERKS ARE INACTIVATED | 13 | 9.96e-01 | 8.53e-04 | 1.000000 |
| REACTOME TNFR1 INDUCED PROAPOPTOTIC SIGNALING | 23 | 9.96e-01 | -5.34e-04 | 1.000000 |
| REACTOME SUMOYLATION OF INTRACELLULAR RECEPTORS | 29 | 9.97e-01 | 4.24e-04 | 1.000000 |
| REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION | 361 | 9.98e-01 | -7.22e-05 | 1.000000 |
| REACTOME RECYCLING PATHWAY OF L1 | 43 | 9.98e-01 | 1.82e-04 | 1.000000 |
| REACTOME RHO GTPASES ACTIVATE ROCKS | 19 | 9.99e-01 | -2.30e-04 | 1.000000 |
| REACTOME ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING | 23 | 1.00e+00 | -7.52e-05 | 1.000000 |
| REACTOME RAF ACTIVATION | 33 | 1.00e+00 | 1.93e-05 | 1.000000 |
Detailed Gene set reports
REACTOME_INNATE_IMMUNE_SYSTEM
| 227 | |
|---|---|
| set | REACTOME_INNATE_IMMUNE_SYSTEM |
| setSize | 1002 |
| pANOVA | 2.17e-07 |
| s.dist | -0.0968 |
| p.adjustANOVA | 0.000351 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| S100A8 | -12422 |
| DEFA4 | -12414 |
| RNASE3 | -12388 |
| FOLR3 | -12374 |
| AOC1 | -12352 |
| CCL22 | -12347 |
| TARM1 | -12340 |
| CTSG | -12333 |
| FCGR3B | -12321 |
| TREM2 | -12299 |
| MEFV | -12271 |
| MPO | -12269 |
| S100P | -12263 |
| FTL | -12213 |
| LILRB3 | -12183 |
| CPN1 | -12180 |
| S100A7A | -12159 |
| S100A9 | -12138 |
| CD300LB | -12125 |
| CEACAM6 | -12099 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| S100A8 | -12422.0 |
| DEFA4 | -12414.0 |
| RNASE3 | -12388.0 |
| FOLR3 | -12374.0 |
| AOC1 | -12352.0 |
| CCL22 | -12347.0 |
| TARM1 | -12340.0 |
| CTSG | -12333.0 |
| FCGR3B | -12321.0 |
| TREM2 | -12299.0 |
| MEFV | -12271.0 |
| MPO | -12269.0 |
| S100P | -12263.0 |
| FTL | -12213.0 |
| LILRB3 | -12183.0 |
| CPN1 | -12180.0 |
| S100A7A | -12159.0 |
| S100A9 | -12138.0 |
| CD300LB | -12125.0 |
| CEACAM6 | -12099.0 |
| TYROBP | -12086.0 |
| LILRB2 | -12044.0 |
| FGA | -12036.0 |
| RAC2 | -12035.0 |
| CD209 | -12018.0 |
| PGLYRP3 | -11976.0 |
| GNLY | -11953.0 |
| SERPINB10 | -11949.0 |
| TBC1D10C | -11920.0 |
| LPO | -11919.0 |
| C5AR2 | -11914.0 |
| CAMP | -11907.0 |
| ATP6V0D2 | -11890.0 |
| SIRPA | -11868.0 |
| RNASE2 | -11866.0 |
| FGG | -11862.0 |
| FCGR3A | -11856.0 |
| KLRD1 | -11840.0 |
| HSPA6 | -11828.0 |
| CXCR1 | -11815.0 |
| SFTPA2 | -11779.0 |
| BPIFB4 | -11767.0 |
| RHOG | -11758.0 |
| SLPI | -11746.0 |
| SOCS1 | -11700.0 |
| CLEC10A | -11698.0 |
| DEFB1 | -11692.0 |
| SEMG1 | -11655.0 |
| SIGLEC14 | -11654.0 |
| CHI3L1 | -11632.0 |
| C8B | -11623.0 |
| ADGRE3 | -11551.0 |
| BIN2 | -11536.0 |
| ADGRG3 | -11514.0 |
| MS4A2 | -11510.0 |
| DEFB127 | -11503.0 |
| GLIPR1 | -11480.0 |
| RNASE7 | -11477.0 |
| CD33 | -11453.0 |
| PPBP | -11413.0 |
| FCER1A | -11402.0 |
| PI3 | -11389.0 |
| TIMP2 | -11388.0 |
| B4GALT1 | -11324.0 |
| PLPP4 | -11251.0 |
| VAT1 | -11242.0 |
| PSMB7 | -11240.0 |
| PYCARD | -11227.0 |
| RNASE8 | -11209.0 |
| DEFB110 | -11193.0 |
| FCER1G | -11146.0 |
| FABP5 | -11138.0 |
| CD300A | -11128.0 |
| UBE2D2 | -11118.0 |
| FCN2 | -11116.0 |
| CLEC5A | -11115.0 |
| MMP9 | -11092.0 |
| LYZ | -11088.0 |
| LTF | -11083.0 |
| CEACAM3 | -11077.0 |
| PGLYRP1 | -11075.0 |
| ALDH3B1 | -11072.0 |
| TMC6 | -11059.0 |
| OLFM4 | -11050.0 |
| HMGB1 | -11028.0 |
| HSP90B1 | -11026.0 |
| ARHGAP9 | -11010.0 |
| TLR9 | -11001.0 |
| ATP6V1E2 | -10985.0 |
| CHIT1 | -10945.0 |
| S100A7 | -10923.0 |
| MAPK12 | -10918.0 |
| NRAS | -10906.0 |
| CFHR5 | -10898.0 |
| MUCL1 | -10850.0 |
| IFNA7 | -10849.0 |
| C5 | -10844.0 |
| IKBKE | -10829.0 |
| GMFG | -10819.0 |
| DEFB125 | -10762.0 |
| TIFA | -10751.0 |
| TREM1 | -10744.0 |
| APOB | -10737.0 |
| UBA3 | -10731.0 |
| CD3G | -10696.0 |
| ENPP4 | -10657.0 |
| PSMD13 | -10647.0 |
| CAPZA1 | -10609.0 |
| UBE2N | -10604.0 |
| SIGLEC9 | -10599.0 |
| CDA | -10585.0 |
| CTSZ | -10581.0 |
| RASGRP2 | -10579.0 |
| C8A | -10569.0 |
| FADD | -10538.0 |
| MGST1 | -10514.0 |
| PRDX6 | -10475.0 |
| FGR | -10464.0 |
| WIPF3 | -10436.0 |
| FCN3 | -10405.0 |
| MNDA | -10310.0 |
| PADI2 | -10269.0 |
| GRN | -10259.0 |
| PNP | -10243.0 |
| PLAC8 | -10230.0 |
| LCP2 | -10227.0 |
| DEFB118 | -10201.0 |
| HVCN1 | -10189.0 |
| CTSH | -10157.0 |
| IKBIP | -10109.0 |
| ARPC4 | -10108.0 |
| PLAUR | -10090.0 |
| BPIFA2 | -10075.0 |
| BPIFB6 | -10052.0 |
| GSN | -10042.0 |
| ACTB | -10011.0 |
| CTSC | -10009.0 |
| ICAM3 | -9983.0 |
| IFNA1 | -9959.0 |
| MAPK13 | -9948.0 |
| SLC11A1 | -9944.0 |
| ATP6V1D | -9942.0 |
| PSMC5 | -9926.0 |
| ORMDL3 | -9925.0 |
| UNC93B1 | -9914.0 |
| ACTG1 | -9912.0 |
| GRB2 | -9911.0 |
| TLR3 | -9905.0 |
| SLC27A2 | -9901.0 |
| MS4A3 | -9898.0 |
| PTPRC | -9874.0 |
| PPP3CB | -9853.0 |
| NPC2 | -9815.0 |
| ARL8A | -9805.0 |
| MBL2 | -9794.0 |
| TXK | -9769.0 |
| IMPDH2 | -9763.0 |
| C4BPA | -9653.0 |
| PSMB3 | -9639.0 |
| UNC13D | -9604.0 |
| LCN2 | -9600.0 |
| PSTPIP1 | -9594.0 |
| PLEKHO2 | -9548.0 |
| ATP6V1B2 | -9537.0 |
| C2 | -9536.0 |
| RAB31 | -9434.0 |
| OLR1 | -9425.0 |
| AHSG | -9421.0 |
| CD93 | -9386.0 |
| ORM1 | -9361.0 |
| CR1 | -9360.0 |
| IRAG2 | -9357.0 |
| CHRNB4 | -9273.0 |
| C1QA | -9271.0 |
| PELI3 | -9269.0 |
| FTH1 | -9258.0 |
| AMPD3 | -9240.0 |
| GM2A | -9227.0 |
| COTL1 | -9216.0 |
| NCKIPSD | -9187.0 |
| AIM2 | -9182.0 |
| PRKCD | -9181.0 |
| EPPIN-WFDC6 | -9173.0 |
| B2M | -9168.0 |
| CD180 | -9158.0 |
| BCL10 | -9151.0 |
| SLC15A4 | -9147.0 |
| DEGS1 | -9107.0 |
| CEACAM1 | -9075.0 |
| CRISP3 | -9069.0 |
| POLR3GL | -9051.0 |
| PSMC4 | -9044.0 |
| PSMB4 | -9031.0 |
| POLR2E | -9019.0 |
| RIPK3 | -9018.0 |
| FUCA1 | -9007.0 |
| IDH1 | -8945.0 |
| CD63 | -8928.0 |
| NLRC4 | -8873.0 |
| RPS27A | -8850.0 |
| ARPC2 | -8781.0 |
| NCKAP1L | -8778.0 |
| EEF1A1 | -8773.0 |
| POLR2L | -8763.0 |
| CD36 | -8750.0 |
| NFASC | -8740.0 |
| FOS | -8732.0 |
| CDK13 | -8705.0 |
| GAB2 | -8677.0 |
| TUBB | -8667.0 |
| PSME2 | -8655.0 |
| ACTR10 | -8617.0 |
| PSMC2 | -8605.0 |
| CR2 | -8588.0 |
| PSMC3 | -8583.0 |
| TUBB4B | -8578.0 |
| TKFC | -8552.0 |
| PTPRJ | -8503.0 |
| HMOX2 | -8490.0 |
| SIGLEC15 | -8482.0 |
| APP | -8452.0 |
| CRISPLD2 | -8440.0 |
| PSMB8 | -8422.0 |
| PELI2 | -8420.0 |
| ASAH1 | -8416.0 |
| CTSD | -8389.0 |
| FBXW11 | -8388.0 |
| NFAM1 | -8344.0 |
| SARM1 | -8323.0 |
| MUC15 | -8307.0 |
| PTAFR | -8264.0 |
| STAT6 | -8263.0 |
| S100A12 | -8236.0 |
| LRG1 | -8209.0 |
| PYGL | -8193.0 |
| LGMN | -8182.0 |
| GZMM | -8167.0 |
| CD300E | -8152.0 |
| AGPAT2 | -8125.0 |
| ALDOC | -8031.0 |
| C7 | -8008.0 |
| RAB27A | -7993.0 |
| TLR6 | -7989.0 |
| MIF | -7988.0 |
| BST1 | -7984.0 |
| PSMB1 | -7961.0 |
| HSPA1A | -7929.0 |
| GPR84 | -7879.0 |
| DEFB133 | -7876.0 |
| CLEC4E | -7871.0 |
| CEACAM8 | -7864.0 |
| BPI | -7862.0 |
| ELANE | -7850.0 |
| POLR3D | -7817.0 |
| GYG1 | -7795.0 |
| APRT | -7775.0 |
| TLR5 | -7754.0 |
| CDC42 | -7738.0 |
| SRC | -7717.0 |
| PSMD11 | -7679.0 |
| PRKACA | -7677.0 |
| PSMD12 | -7653.0 |
| CD177 | -7620.0 |
| TOM1 | -7615.0 |
| SFTPD | -7570.0 |
| UBC | -7516.0 |
| SKP1 | -7505.0 |
| MUC17 | -7484.0 |
| USP14 | -7429.0 |
| PKM | -7388.0 |
| WASF3 | -7381.0 |
| HP | -7374.0 |
| STOM | -7309.0 |
| PTK2 | -7305.0 |
| C1QC | -7269.0 |
| RNASET2 | -7253.0 |
| DEFB121 | -7228.0 |
| BCL2 | -7205.0 |
| PSMA1 | -7186.0 |
| MGAM | -7145.0 |
| DSN1 | -7105.0 |
| APAF1 | -7090.0 |
| SCAMP1 | -7072.0 |
| LBP | -7062.0 |
| PTX3 | -7033.0 |
| ILF2 | -7027.0 |
| GCA | -6988.0 |
| DEFB124 | -6969.0 |
| PLA2G2A | -6966.0 |
| TRIM4 | -6964.0 |
| BCL2L1 | -6947.0 |
| VAV2 | -6903.0 |
| PPP2R1A | -6897.0 |
| TTR | -6894.0 |
| UBE2K | -6887.0 |
| TSPAN14 | -6882.0 |
| C5AR1 | -6869.0 |
| MUC16 | -6831.0 |
| NBEAL2 | -6825.0 |
| MAPK11 | -6815.0 |
| CPB2 | -6812.0 |
| MRE11 | -6761.0 |
| VAV1 | -6738.0 |
| CRP | -6729.0 |
| CTSL | -6722.0 |
| DUSP7 | -6711.0 |
| SAA1 | -6701.0 |
| SERPINA3 | -6685.0 |
| PCBP2 | -6678.0 |
| MANBA | -6629.0 |
| MUC7 | -6620.0 |
| DIAPH1 | -6610.0 |
| NOS3 | -6594.0 |
| IFNA5 | -6575.0 |
| UBE2M | -6564.0 |
| CD55 | -6560.0 |
| UBB | -6558.0 |
| PGLYRP4 | -6540.0 |
| CLEC12A | -6505.0 |
| RNF125 | -6496.0 |
| PSMD4 | -6474.0 |
| ATP6V0E1 | -6427.0 |
| HEBP2 | -6416.0 |
| MAP3K1 | -6369.0 |
| IFNA8 | -6348.0 |
| CFL1 | -6343.0 |
| PIK3CA | -6283.0 |
| PTPN6 | -6254.0 |
| NME2 | -6239.0 |
| SLC2A5 | -6217.0 |
| ALOX5 | -6199.0 |
| P2RX1 | -6180.0 |
| PRKACB | -6133.0 |
| OSCAR | -6111.0 |
| DSG1 | -6110.0 |
| C1S | -6102.0 |
| PSMB5 | -6101.0 |
| A1BG | -6098.0 |
| TOMM70 | -6036.0 |
| PIK3R2 | -6034.0 |
| MMP25 | -6014.0 |
| DYNLL1 | -6011.0 |
| PPP2CB | -5989.0 |
| PSMB9 | -5962.0 |
| HCK | -5951.0 |
| PRG3 | -5936.0 |
| WIPF1 | -5917.0 |
| VTN | -5914.0 |
| TAB1 | -5788.0 |
| PSMA7 | -5784.0 |
| COLEC10 | -5739.0 |
| ABI1 | -5737.0 |
| CKAP4 | -5734.0 |
| DEFB126 | -5727.0 |
| NFKB1 | -5696.0 |
| PIK3R1 | -5692.0 |
| RNF135 | -5687.0 |
| RAC1 | -5651.0 |
| TNIP2 | -5610.0 |
| DNM2 | -5584.0 |
| PSMD3 | -5582.0 |
| SLC2A3 | -5557.0 |
| C1orf35 | -5547.0 |
| ALPK1 | -5537.0 |
| PSEN1 | -5526.0 |
| S100B | -5493.0 |
| AAMP | -5477.0 |
| GSDMD | -5447.0 |
| ATP6V1B1 | -5410.0 |
| SYK | -5379.0 |
| CD46 | -5362.0 |
| HLA-E | -5359.0 |
| SERPINB12 | -5298.0 |
| MVP | -5291.0 |
| PSMA4 | -5279.0 |
| ELMO2 | -5213.0 |
| PIGR | -5159.0 |
| ATF1 | -5139.0 |
| PSAP | -5129.0 |
| PSMB11 | -5123.0 |
| FGB | -5103.0 |
| CTSV | -5082.0 |
| DUSP4 | -5038.0 |
| PSMA2 | -5037.0 |
| IST1 | -5013.0 |
| TRAF2 | -5005.0 |
| MUC20 | -4962.0 |
| CD59 | -4936.0 |
| DEFB136 | -4917.0 |
| ITPR2 | -4886.0 |
| NF2 | -4857.0 |
| PIK3C3 | -4824.0 |
| ATP6V1F | -4792.0 |
| PRCP | -4779.0 |
| SERPINA1 | -4767.0 |
| DOCK2 | -4746.0 |
| SURF4 | -4668.0 |
| ITK | -4661.0 |
| C4BPB | -4653.0 |
| PRTN3 | -4641.0 |
| PLD1 | -4639.0 |
| PLD3 | -4629.0 |
| KLRK1 | -4600.0 |
| MAP2K1 | -4569.0 |
| PLAU | -4561.0 |
| RAB18 | -4479.0 |
| ITGAL | -4475.0 |
| NKIRAS2 | -4464.0 |
| MAP2K3 | -4456.0 |
| DHX36 | -4451.0 |
| FPR2 | -4431.0 |
| PSMB10 | -4396.0 |
| HSPA1B | -4389.0 |
| C6 | -4374.0 |
| MAPK10 | -4368.0 |
| CSNK2B | -4328.0 |
| PDAP1 | -4312.0 |
| PSME4 | -4311.0 |
| DYNC1LI1 | -4284.0 |
| ATP6V0B | -4280.0 |
| DHX9 | -4278.0 |
| F2 | -4275.0 |
| LRRFIP1 | -4234.0 |
| PSMA6 | -4225.0 |
| CLU | -4204.0 |
| ADAM10 | -4196.0 |
| LRRC7 | -4165.0 |
| CAT | -4127.0 |
| DEFB129 | -4113.0 |
| IRAK2 | -4078.0 |
| SERPING1 | -4072.0 |
| MYO10 | -4070.0 |
| TRIM25 | -4067.0 |
| CNPY3 | -4047.0 |
| ECSIT | -4010.0 |
| DDX41 | -3993.0 |
| HTN3 | -3991.0 |
| BIRC3 | -3927.0 |
| DEFB119 | -3918.0 |
| CCT8 | -3865.0 |
| BAIAP2 | -3848.0 |
| CD68 | -3811.0 |
| NKIRAS1 | -3807.0 |
| CPNE3 | -3799.0 |
| RAB44 | -3786.0 |
| IFNA2 | -3772.0 |
| SYNGR1 | -3766.0 |
| LIMK1 | -3755.0 |
| NFATC2 | -3728.0 |
| UBE2D3 | -3713.0 |
| MAPK14 | -3702.0 |
| DEFB115 | -3693.0 |
| STK10 | -3676.0 |
| RAB3A | -3628.0 |
| TLR4 | -3591.0 |
| ABL1 | -3561.0 |
| NFATC3 | -3517.0 |
| MAP3K14 | -3430.0 |
| LTA4H | -3379.0 |
| CLEC4C | -3368.0 |
| VNN1 | -3340.0 |
| BPIFB2 | -3337.0 |
| ATP8A1 | -3334.0 |
| MUC12 | -3332.0 |
| FCAR | -3306.0 |
| HPSE | -3281.0 |
| DGAT1 | -3224.0 |
| QPCT | -3198.0 |
| MYH9 | -3191.0 |
| MLEC | -3190.0 |
| MYD88 | -3176.0 |
| CLEC4A | -3136.0 |
| ATG12 | -3122.0 |
| RAB7A | -3074.0 |
| PTPRB | -3070.0 |
| WASL | -3046.0 |
| COMMD9 | -3040.0 |
| PSMD8 | -3004.0 |
| RAF1 | -2997.0 |
| SRP14 | -2981.0 |
| POLR2K | -2963.0 |
| RAB37 | -2962.0 |
| COLEC11 | -2954.0 |
| RAP1B | -2948.0 |
| DERA | -2936.0 |
| PRKCQ | -2828.0 |
| POLR3H | -2745.0 |
| MYO1C | -2720.0 |
| CYSTM1 | -2717.0 |
| SLC44A2 | -2693.0 |
| PSMD9 | -2679.0 |
| KCMF1 | -2671.0 |
| DUSP3 | -2653.0 |
| YPEL5 | -2635.0 |
| ACTR1B | -2615.0 |
| NAPRT | -2599.0 |
| IFI16 | -2591.0 |
| RNF216 | -2589.0 |
| DOCK1 | -2571.0 |
| PA2G4 | -2556.0 |
| LCK | -2552.0 |
| SNAP25 | -2543.0 |
| CSTB | -2505.0 |
| RASGRP1 | -2502.0 |
| PRG2 | -2501.0 |
| ACP3 | -2497.0 |
| NCSTN | -2455.0 |
| DBNL | -2415.0 |
| PLD4 | -2414.0 |
| CYBA | -2406.0 |
| CHGA | -2328.0 |
| TRIM21 | -2322.0 |
| PKP1 | -2282.0 |
| TMEM30A | -2276.0 |
| AHCYL1 | -2267.0 |
| DDOST | -2258.0 |
| PSMD1 | -2198.0 |
| S100A1 | -2145.0 |
| ABCA13 | -2129.0 |
| C9 | -2114.0 |
| SIGIRR | -2077.0 |
| MUC3A | -2057.0 |
| CCR6 | -2053.0 |
| FGL2 | -2051.0 |
| GOLGA7 | -2050.0 |
| MEF2A | -2036.0 |
| NFKBIA | -2009.0 |
| CAPZA2 | -2008.0 |
| ABI2 | -1931.0 |
| CFB | -1927.0 |
| ACTR3 | -1924.0 |
| NOS1 | -1872.0 |
| CAND1 | -1857.0 |
| RAB3D | -1844.0 |
| IFIH1 | -1831.0 |
| ARMC8 | -1830.0 |
| SHC1 | -1802.0 |
| IRF7 | -1773.0 |
| TMEM63A | -1768.0 |
| KPNB1 | -1727.0 |
| GNS | -1708.0 |
| LILRA3 | -1707.0 |
| MAPK1 | -1683.0 |
| CFHR4 | -1678.0 |
| NCF2 | -1640.0 |
| TMBIM1 | -1565.0 |
| CFI | -1553.0 |
| HERC5 | -1537.0 |
| HLA-B | -1486.0 |
| CLEC4D | -1441.0 |
| UBR4 | -1384.0 |
| C1QB | -1375.0 |
| ATP6V0A1 | -1371.0 |
| PPP3R1 | -1350.0 |
| ARPC1A | -1335.0 |
| TRAF6 | -1333.0 |
| BST2 | -1266.0 |
| NOD1 | -1253.0 |
| GRAP2 | -1248.0 |
| DOK3 | -1231.0 |
| RAB6A | -1197.0 |
| FYN | -1185.0 |
| STBD1 | -1128.0 |
| ELMO1 | -1111.0 |
| RPS6KA1 | -1101.0 |
| PRSS3 | -1098.0 |
| HSP90AA1 | -1097.0 |
| PLCG1 | -1095.0 |
| DNAJC3 | -1068.0 |
| NCF4 | -1029.0 |
| TBK1 | -1012.0 |
| CFD | -969.0 |
| PSMD14 | -968.0 |
| ADGRE5 | -958.0 |
| DNM1 | -921.0 |
| GSDME | -899.0 |
| GDI2 | -889.0 |
| LAMTOR2 | -845.0 |
| CD53 | -822.0 |
| ITCH | -817.0 |
| CRCP | -792.0 |
| ITGB2 | -786.0 |
| P2RX7 | -782.0 |
| PPP3CA | -777.0 |
| MUC13 | -735.0 |
| DYNLT1 | -713.0 |
| ANPEP | -709.0 |
| XRCC5 | -707.0 |
| DEFB134 | -657.0 |
| MAVS | -613.0 |
| EPX | -596.0 |
| POLR3C | -592.0 |
| HSP90AB1 | -579.0 |
| POLR3G | -558.0 |
| ARHGAP45 | -501.0 |
| STING1 | -479.0 |
| ACTR2 | -466.0 |
| POLR3A | -462.0 |
| PRKCE | -460.0 |
| DEFB132 | -450.0 |
| REG3G | -448.0 |
| CMTM6 | -422.0 |
| CD47 | -413.0 |
| RHOF | -398.0 |
| RASGRP4 | -397.0 |
| NFKBIB | -386.0 |
| RAP1A | -384.0 |
| TRPM2 | -378.0 |
| CREG1 | -369.0 |
| OSTF1 | -354.0 |
| FCN1 | -340.0 |
| TNFAIP3 | -320.0 |
| MAP2K6 | -317.0 |
| DEFB114 | -223.0 |
| ARSA | -183.0 |
| MUC21 | -178.0 |
| GHDC | -167.0 |
| GUSB | -113.0 |
| NOS2 | -93.0 |
| VRK3 | -78.0 |
| DEFB116 | -48.0 |
| DHX58 | -32.0 |
| PGM2 | -23.0 |
| C4A | -13.5 |
| C4B | -13.5 |
| SUGT1 | -6.0 |
| PYGB | 19.0 |
| ALDOA | 25.0 |
| PSMD5 | 47.0 |
| ATP6V1E1 | 60.0 |
| KRAS | 94.0 |
| ZBP1 | 143.0 |
| CNN2 | 183.0 |
| LAMTOR1 | 215.0 |
| TREX1 | 257.0 |
| TXN | 273.0 |
| VAMP8 | 328.0 |
| HTN1 | 374.0 |
| TXNIP | 376.0 |
| SFTPA1 | 386.0 |
| ATP6V0A4 | 420.0 |
| TAB2 | 430.0 |
| HRAS | 462.0 |
| JUP | 465.0 |
| BPIFA1 | 469.0 |
| NFKB2 | 477.0 |
| N4BP1 | 490.0 |
| MAP3K8 | 500.0 |
| CFHR2 | 520.0 |
| POLR1C | 574.0 |
| BPIFB1 | 598.0 |
| NHLRC3 | 611.0 |
| AGL | 667.0 |
| POLR3F | 692.0 |
| MAPK8 | 717.0 |
| POLR2F | 722.0 |
| PRKCSH | 735.0 |
| POLR2H | 760.0 |
| PSMA3 | 761.0 |
| TMEM179B | 811.0 |
| SERPINB6 | 915.0 |
| RAB10 | 940.0 |
| MAP3K7 | 959.0 |
| ROCK1 | 965.0 |
| PIK3R4 | 968.0 |
| CEP290 | 1033.0 |
| CYLD | 1046.0 |
| PECAM1 | 1067.0 |
| ITPR1 | 1071.0 |
| MAPK7 | 1074.0 |
| CASP9 | 1145.0 |
| IRF3 | 1158.0 |
| MAPK3 | 1159.0 |
| PAFAH1B2 | 1161.0 |
| RAP2B | 1165.0 |
| GSTP1 | 1170.0 |
| RPS6KA2 | 1176.0 |
| AZU1 | 1191.0 |
| DUSP6 | 1204.0 |
| CYB5R3 | 1237.0 |
| PSMD6 | 1244.0 |
| STK11IP | 1266.0 |
| PAK2 | 1282.0 |
| NLRP3 | 1284.0 |
| SDCBP | 1329.0 |
| XRCC6 | 1347.0 |
| TLR10 | 1354.0 |
| TLR1 | 1380.0 |
| MCEMP1 | 1408.0 |
| ATG7 | 1417.0 |
| ATG5 | 1439.0 |
| HK3 | 1481.0 |
| MASP1 | 1503.0 |
| ARPC1B | 1507.0 |
| ATP6V0C | 1512.0 |
| VAPA | 1513.0 |
| NCK1 | 1544.0 |
| IQGAP1 | 1557.0 |
| SELL | 1560.0 |
| WASF1 | 1561.0 |
| PTPRN2 | 1564.0 |
| ITGAX | 1566.0 |
| VPS35L | 1567.0 |
| NLRC3 | 1599.0 |
| PSME3 | 1619.0 |
| PLD2 | 1631.0 |
| TRIM32 | 1639.0 |
| ATP6V1G2 | 1640.0 |
| HLA-A | 1643.0 |
| ATP6V1H | 1664.0 |
| HGSNAT | 1665.0 |
| CXCR2 | 1666.0 |
| HSPA8 | 1683.0 |
| PPP2CA | 1705.0 |
| FAF2 | 1719.0 |
| CYFIP1 | 1733.0 |
| PPIA | 1750.0 |
| CD247 | 1766.0 |
| CD44 | 1832.0 |
| MASP2 | 1838.0 |
| POLR3K | 1853.0 |
| PPP2R1B | 1865.0 |
| NCR2 | 1871.0 |
| CREBBP | 1880.0 |
| SPTAN1 | 1882.0 |
| IFNA13 | 1939.0 |
| RAB14 | 1952.0 |
| SEM1 | 1961.0 |
| DNM3 | 2004.0 |
| HLA-C | 2005.0 |
| CST3 | 2013.0 |
| VAV3 | 2014.0 |
| POLR3B | 2025.0 |
| WIPF2 | 2048.0 |
| PSMB2 | 2057.0 |
| UBE2V1 | 2128.0 |
| PDXK | 2151.0 |
| CTSS | 2170.0 |
| SNAP29 | 2184.0 |
| PTPN11 | 2193.0 |
| ANO6 | 2222.0 |
| RAB4B | 2243.0 |
| ART1 | 2248.0 |
| TRIM56 | 2262.0 |
| MUC5AC | 2282.0 |
| CARD9 | 2287.0 |
| ITGAM | 2304.0 |
| PROS1 | 2314.0 |
| BIRC2 | 2323.0 |
| UBE2D1 | 2345.0 |
| CTSA | 2375.0 |
| PIK3CB | 2393.0 |
| MALT1 | 2452.0 |
| MYO9B | 2511.0 |
| SERPINB1 | 2512.0 |
| CTNNB1 | 2534.0 |
| PSMA5 | 2542.0 |
| LAT | 2546.0 |
| MAPKAPK3 | 2592.0 |
| QSOX1 | 2616.0 |
| IRAK3 | 2625.0 |
| ATP11B | 2635.0 |
| PSME1 | 2636.0 |
| CD81 | 2666.0 |
| PLPP5 | 2690.0 |
| PSMB6 | 2700.0 |
| FRK | 2713.0 |
| USP18 | 2727.0 |
| TNFRSF1B | 2797.0 |
| CUL1 | 2803.0 |
| LYN | 2809.0 |
| CTSK | 2842.0 |
| RIPK1 | 2869.0 |
| MME | 2873.0 |
| YES1 | 2889.0 |
| LPCAT1 | 2901.0 |
| PAK1 | 2920.0 |
| PGAM1 | 2941.0 |
| LY86 | 2960.0 |
| CAPN1 | 2973.0 |
| NDUFC2 | 3031.0 |
| S100A11 | 3059.0 |
| MAPK9 | 3064.0 |
| PGM1 | 3074.0 |
| ITGAV | 3093.0 |
| ARPC5 | 3103.0 |
| MAPKAPK2 | 3174.0 |
| CAP1 | 3198.0 |
| CRACR2A | 3212.0 |
| ARPC3 | 3227.0 |
| CFH | 3256.0 |
| SIKE1 | 3286.0 |
| CPNE1 | 3300.0 |
| PSMD2 | 3383.0 |
| PSMC6 | 3448.0 |
| MAP2K4 | 3450.0 |
| BTRC | 3451.0 |
| TANK | 3506.0 |
| PPP2R5D | 3535.0 |
| PLCG2 | 3580.0 |
| TAX1BP1 | 3584.0 |
| RAB5C | 3602.0 |
| CYFIP2 | 3606.0 |
| RPS6KA5 | 3633.0 |
| VCL | 3647.0 |
| MAN2B1 | 3662.0 |
| MEF2C | 3665.0 |
| PANX1 | 3689.0 |
| CGAS | 3702.0 |
| ATP6V1G1 | 3708.0 |
| ATP6V0E2 | 3779.0 |
| DCD | 3789.0 |
| ACLY | 3821.0 |
| FCGR2A | 3837.0 |
| RELB | 3868.0 |
| C8G | 3882.0 |
| HEXB | 3888.0 |
| C3 | 3889.0 |
| JUN | 3936.0 |
| BRI3 | 3964.0 |
| EP300 | 3970.0 |
| NCKAP1 | 3976.0 |
| RAB5B | 4015.0 |
| LRRC14 | 4019.0 |
| ARSB | 4029.0 |
| DPP7 | 4062.0 |
| PIN1 | 4069.0 |
| CALML5 | 4110.0 |
| ERP44 | 4123.0 |
| CALM1 | 4126.0 |
| TCIRG1 | 4135.0 |
| CTSB | 4194.0 |
| KCNAB2 | 4244.0 |
| TNFAIP6 | 4255.0 |
| LAT2 | 4284.0 |
| TP53 | 4288.0 |
| UBA52 | 4371.0 |
| REG3A | 4372.0 |
| ANXA2 | 4374.0 |
| KRT1 | 4388.0 |
| HBB | 4410.0 |
| GAA | 4446.0 |
| CD58 | 4480.0 |
| TICAM2 | 4515.0 |
| LAMTOR3 | 4577.0 |
| ADAM8 | 4598.0 |
| RAB24 | 4624.0 |
| SOS1 | 4627.0 |
| IGF2R | 4652.0 |
| POLR1D | 4720.0 |
| ATP6V0D1 | 4724.0 |
| ATOX1 | 4725.0 |
| EPPIN | 4770.0 |
| DTX4 | 4881.0 |
| NLRC5 | 4911.0 |
| RHOA | 4928.0 |
| GLB1 | 4936.0 |
| PDPK1 | 4953.0 |
| MYO5A | 4997.0 |
| ATP6V1G3 | 5008.0 |
| PSMC1 | 5036.0 |
| PELI1 | 5040.0 |
| CD14 | 5065.0 |
| UBE2L6 | 5145.0 |
| MYH2 | 5187.0 |
| LAIR1 | 5189.0 |
| ATP6V1A | 5213.0 |
| IQGAP2 | 5324.0 |
| AGA | 5326.0 |
| SNAP23 | 5360.0 |
| CLEC7A | 5403.0 |
| ATP6V1C1 | 5445.0 |
| CASP8 | 5451.0 |
| ITPR3 | 5458.0 |
| TEC | 5461.0 |
| IMPDH1 | 5488.0 |
| PSMD7 | 5490.0 |
| EEA1 | 5521.0 |
| CASP1 | 5568.0 |
| TIRAP | 5595.0 |
| IFNA14 | 5600.0 |
| VCP | 5713.0 |
| DSP | 5721.0 |
| TRAPPC1 | 5725.0 |
| C6orf120 | 5727.0 |
| SERPINB3 | 5770.0 |
| FLG2 | 5773.0 |
| TXNDC5 | 5786.0 |
| NLRX1 | 5804.0 |
| HMOX1 | 5812.0 |
| PFKL | 5851.0 |
| APEH | 5853.0 |
| PTPN4 | 5859.0 |
| PTGES2 | 5866.0 |
| ATF2 | 5884.0 |
| SVIP | 5951.0 |
| C1R | 5971.0 |
| CAB39 | 5988.0 |
| COPB1 | 5990.0 |
| ARG1 | 6006.0 |
| CCL17 | 6028.0 |
| GGH | 6079.0 |
| AP2A2 | 6101.0 |
| RIPK2 | 6140.0 |
| EEF2 | 6286.0 |
| NEU1 | 6335.0 |
| PSMF1 | 6349.0 |
| ORM2 | 6384.0 |
| ATP6V0A2 | 6396.0 |
| DNAJC13 | 6440.0 |
| DSC1 | 6497.0 |
| TICAM1 | 6502.0 |
| RBSN | 6526.0 |
| DNAJC5 | 6570.0 |
| DYNC1H1 | 6590.0 |
| ATP6V1C2 | 6639.0 |
| GALNS | 6649.0 |
| WASF2 | 6677.0 |
| GPI | 6696.0 |
| TOLLIP | 6727.0 |
| CD19 | 6744.0 |
| ADA2 | 6759.0 |
| ATP8B4 | 6780.0 |
| TRAF3 | 6785.0 |
| DEFB123 | 6800.0 |
| ACAA1 | 6816.0 |
| BRK1 | 6834.0 |
| NOD2 | 6837.0 |
| MUC6 | 6853.0 |
| CPPED1 | 6870.0 |
| LEAP2 | 6935.0 |
| RIGI | 7021.0 |
| TLR2 | 7026.0 |
| NLRP4 | 7045.0 |
| CREB1 | 7072.0 |
| CCT2 | 7076.0 |
| POLR3E | 7088.0 |
| CANT1 | 7122.0 |
| MUC5B | 7242.0 |
| MUC1 | 7245.0 |
| UBA7 | 7274.0 |
| PRKDC | 7319.0 |
| IL1B | 7336.0 |
| TCN1 | 7348.0 |
| ATAD3B | 7374.0 |
| CARD11 | 7389.0 |
| CPN2 | 7444.0 |
| ATP11A | 7460.0 |
| DEFB104A | 7492.5 |
| DEFB104B | 7492.5 |
| CASP4 | 7503.0 |
| NLRP1 | 7539.0 |
| NIT2 | 7562.0 |
| CXCL1 | 7640.0 |
| SLCO4C1 | 7669.0 |
| IRAK4 | 7688.0 |
| CRK | 7732.0 |
| FUCA2 | 7735.0 |
| NFATC1 | 7770.0 |
| MUC4 | 7777.0 |
| ALAD | 7841.0 |
| IKBKB | 7889.0 |
| PPIE | 7929.0 |
| FPR1 | 7940.0 |
| CASP2 | 7942.0 |
| COMMD3 | 7946.0 |
| DEFB113 | 7980.0 |
| CASP10 | 8135.0 |
| LGALS3 | 8154.0 |
| MAP2K7 | 8159.0 |
| PSMA8 | 8189.0 |
| RNASE6 | 8250.0 |
| SIGLEC5 | 8257.0 |
| CLEC6A | 8274.0 |
| PLA2G6 | 8321.0 |
| DEFA5 | 8324.0 |
| MMP8 | 8345.0 |
| CDC34 | 8372.0 |
| IFNA6 | 8378.0 |
| CD4 | 8382.0 |
| SIRPB1 | 8404.0 |
| DEFB128 | 8594.0 |
| CHUK | 8602.0 |
| AP1M1 | 8630.0 |
| LY96 | 8637.0 |
| ISG15 | 8677.0 |
| RELA | 8703.0 |
| LAMP1 | 8730.0 |
| IFNA16 | 8795.0 |
| IFNB1 | 8825.0 |
| C3AR1 | 8829.0 |
| HRNR | 8850.0 |
| AGER | 8867.0 |
| RETN | 8884.0 |
| PGLYRP2 | 8958.0 |
| CCR2 | 9046.0 |
| ICAM2 | 9169.0 |
| PRKACG | 9172.0 |
| ITLN1 | 9256.0 |
| DEFB135 | 9316.0 |
| DEFA6 | 9331.0 |
| IFNA21 | 9565.0 |
REACTOME_NEUTROPHIL_DEGRANULATION
| 1053 | |
|---|---|
| set | REACTOME_NEUTROPHIL_DEGRANULATION |
| setSize | 460 |
| pANOVA | 4.28e-07 |
| s.dist | -0.138 |
| p.adjustANOVA | 0.000351 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| S100A8 | -12422 |
| DEFA4 | -12414 |
| RNASE3 | -12388 |
| FOLR3 | -12374 |
| AOC1 | -12352 |
| TARM1 | -12340 |
| CTSG | -12333 |
| FCGR3B | -12321 |
| MPO | -12269 |
| S100P | -12263 |
| FTL | -12213 |
| LILRB3 | -12183 |
| S100A9 | -12138 |
| CEACAM6 | -12099 |
| TYROBP | -12086 |
| LILRB2 | -12044 |
| SERPINB10 | -11949 |
| TBC1D10C | -11920 |
| CAMP | -11907 |
| SIRPA | -11868 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| S100A8 | -12422 |
| DEFA4 | -12414 |
| RNASE3 | -12388 |
| FOLR3 | -12374 |
| AOC1 | -12352 |
| TARM1 | -12340 |
| CTSG | -12333 |
| FCGR3B | -12321 |
| MPO | -12269 |
| S100P | -12263 |
| FTL | -12213 |
| LILRB3 | -12183 |
| S100A9 | -12138 |
| CEACAM6 | -12099 |
| TYROBP | -12086 |
| LILRB2 | -12044 |
| SERPINB10 | -11949 |
| TBC1D10C | -11920 |
| CAMP | -11907 |
| SIRPA | -11868 |
| RNASE2 | -11866 |
| HSPA6 | -11828 |
| CXCR1 | -11815 |
| RHOG | -11758 |
| SLPI | -11746 |
| SIGLEC14 | -11654 |
| CHI3L1 | -11632 |
| ADGRE3 | -11551 |
| BIN2 | -11536 |
| ADGRG3 | -11514 |
| GLIPR1 | -11480 |
| CD33 | -11453 |
| PPBP | -11413 |
| TIMP2 | -11388 |
| B4GALT1 | -11324 |
| VAT1 | -11242 |
| PSMB7 | -11240 |
| PYCARD | -11227 |
| FCER1G | -11146 |
| FABP5 | -11138 |
| CD300A | -11128 |
| CLEC5A | -11115 |
| MMP9 | -11092 |
| LYZ | -11088 |
| LTF | -11083 |
| CEACAM3 | -11077 |
| PGLYRP1 | -11075 |
| ALDH3B1 | -11072 |
| TMC6 | -11059 |
| OLFM4 | -11050 |
| HMGB1 | -11028 |
| ARHGAP9 | -11010 |
| CHIT1 | -10945 |
| S100A7 | -10923 |
| NRAS | -10906 |
| GMFG | -10819 |
| ENPP4 | -10657 |
| PSMD13 | -10647 |
| SIGLEC9 | -10599 |
| CDA | -10585 |
| CTSZ | -10581 |
| MGST1 | -10514 |
| PRDX6 | -10475 |
| FGR | -10464 |
| MNDA | -10310 |
| PADI2 | -10269 |
| GRN | -10259 |
| PNP | -10243 |
| PLAC8 | -10230 |
| HVCN1 | -10189 |
| CTSH | -10157 |
| PLAUR | -10090 |
| GSN | -10042 |
| CTSC | -10009 |
| SLC11A1 | -9944 |
| ATP6V1D | -9942 |
| ORMDL3 | -9925 |
| SLC27A2 | -9901 |
| MS4A3 | -9898 |
| PTPRC | -9874 |
| NPC2 | -9815 |
| ARL8A | -9805 |
| IMPDH2 | -9763 |
| UNC13D | -9604 |
| LCN2 | -9600 |
| PLEKHO2 | -9548 |
| RAB31 | -9434 |
| OLR1 | -9425 |
| AHSG | -9421 |
| CD93 | -9386 |
| ORM1 | -9361 |
| CR1 | -9360 |
| IRAG2 | -9357 |
| CHRNB4 | -9273 |
| FTH1 | -9258 |
| AMPD3 | -9240 |
| GM2A | -9227 |
| COTL1 | -9216 |
| PRKCD | -9181 |
| B2M | -9168 |
| SLC15A4 | -9147 |
| DEGS1 | -9107 |
| CEACAM1 | -9075 |
| CRISP3 | -9069 |
| FUCA1 | -9007 |
| IDH1 | -8945 |
| CD63 | -8928 |
| NCKAP1L | -8778 |
| EEF1A1 | -8773 |
| CD36 | -8750 |
| NFASC | -8740 |
| CDK13 | -8705 |
| TUBB | -8667 |
| ACTR10 | -8617 |
| PSMC2 | -8605 |
| PSMC3 | -8583 |
| TUBB4B | -8578 |
| PTPRJ | -8503 |
| HMOX2 | -8490 |
| CRISPLD2 | -8440 |
| ASAH1 | -8416 |
| CTSD | -8389 |
| NFAM1 | -8344 |
| PTAFR | -8264 |
| S100A12 | -8236 |
| LRG1 | -8209 |
| PYGL | -8193 |
| AGPAT2 | -8125 |
| ALDOC | -8031 |
| RAB27A | -7993 |
| MIF | -7988 |
| BST1 | -7984 |
| PSMB1 | -7961 |
| HSPA1A | -7929 |
| GPR84 | -7879 |
| CEACAM8 | -7864 |
| BPI | -7862 |
| ELANE | -7850 |
| GYG1 | -7795 |
| APRT | -7775 |
| PSMD11 | -7679 |
| PSMD12 | -7653 |
| CD177 | -7620 |
| TOM1 | -7615 |
| PKM | -7388 |
| HP | -7374 |
| STOM | -7309 |
| RNASET2 | -7253 |
| MGAM | -7145 |
| DSN1 | -7105 |
| APAF1 | -7090 |
| SCAMP1 | -7072 |
| PTX3 | -7033 |
| ILF2 | -7027 |
| GCA | -6988 |
| TTR | -6894 |
| TSPAN14 | -6882 |
| C5AR1 | -6869 |
| NBEAL2 | -6825 |
| SERPINA3 | -6685 |
| MANBA | -6629 |
| DIAPH1 | -6610 |
| CD55 | -6560 |
| CLEC12A | -6505 |
| HEBP2 | -6416 |
| PTPN6 | -6254 |
| NME2 | -6239 |
| SLC2A5 | -6217 |
| ALOX5 | -6199 |
| P2RX1 | -6180 |
| OSCAR | -6111 |
| DSG1 | -6110 |
| A1BG | -6098 |
| MMP25 | -6014 |
| DYNLL1 | -6011 |
| PRG3 | -5936 |
| CKAP4 | -5734 |
| NFKB1 | -5696 |
| RAC1 | -5651 |
| PSMD3 | -5582 |
| SLC2A3 | -5557 |
| C1orf35 | -5547 |
| PSEN1 | -5526 |
| GSDMD | -5447 |
| SERPINB12 | -5298 |
| MVP | -5291 |
| PIGR | -5159 |
| PSAP | -5129 |
| PSMA2 | -5037 |
| IST1 | -5013 |
| CD59 | -4936 |
| PRCP | -4779 |
| SERPINA1 | -4767 |
| DOCK2 | -4746 |
| SURF4 | -4668 |
| PRTN3 | -4641 |
| PLD1 | -4639 |
| PLAU | -4561 |
| RAB18 | -4479 |
| ITGAL | -4475 |
| FPR2 | -4431 |
| HSPA1B | -4389 |
| CSNK2B | -4328 |
| PDAP1 | -4312 |
| DYNC1LI1 | -4284 |
| ADAM10 | -4196 |
| LRRC7 | -4165 |
| CAT | -4127 |
| CCT8 | -3865 |
| CD68 | -3811 |
| CPNE3 | -3799 |
| RAB44 | -3786 |
| SYNGR1 | -3766 |
| MAPK14 | -3702 |
| STK10 | -3676 |
| RAB3A | -3628 |
| LTA4H | -3379 |
| CLEC4C | -3368 |
| VNN1 | -3340 |
| ATP8A1 | -3334 |
| FCAR | -3306 |
| HPSE | -3281 |
| DGAT1 | -3224 |
| QPCT | -3198 |
| MLEC | -3190 |
| RAB7A | -3074 |
| PTPRB | -3070 |
| COMMD9 | -3040 |
| SRP14 | -2981 |
| RAB37 | -2962 |
| RAP1B | -2948 |
| DERA | -2936 |
| CYSTM1 | -2717 |
| SLC44A2 | -2693 |
| KCMF1 | -2671 |
| YPEL5 | -2635 |
| ACTR1B | -2615 |
| NAPRT | -2599 |
| PA2G4 | -2556 |
| SNAP25 | -2543 |
| CSTB | -2505 |
| PRG2 | -2501 |
| ACP3 | -2497 |
| NCSTN | -2455 |
| DBNL | -2415 |
| CYBA | -2406 |
| PKP1 | -2282 |
| TMEM30A | -2276 |
| DDOST | -2258 |
| PSMD1 | -2198 |
| ABCA13 | -2129 |
| FGL2 | -2051 |
| GOLGA7 | -2050 |
| CAND1 | -1857 |
| RAB3D | -1844 |
| ARMC8 | -1830 |
| TMEM63A | -1768 |
| KPNB1 | -1727 |
| GNS | -1708 |
| LILRA3 | -1707 |
| MAPK1 | -1683 |
| TMBIM1 | -1565 |
| HLA-B | -1486 |
| CLEC4D | -1441 |
| UBR4 | -1384 |
| ATP6V0A1 | -1371 |
| BST2 | -1266 |
| DOK3 | -1231 |
| RAB6A | -1197 |
| STBD1 | -1128 |
| PRSS3 | -1098 |
| HSP90AA1 | -1097 |
| DNAJC3 | -1068 |
| CFD | -969 |
| PSMD14 | -968 |
| ADGRE5 | -958 |
| GDI2 | -889 |
| LAMTOR2 | -845 |
| CD53 | -822 |
| ITGB2 | -786 |
| DYNLT1 | -713 |
| ANPEP | -709 |
| XRCC5 | -707 |
| EPX | -596 |
| HSP90AB1 | -579 |
| ARHGAP45 | -501 |
| STING1 | -479 |
| ACTR2 | -466 |
| CMTM6 | -422 |
| CD47 | -413 |
| RHOF | -398 |
| RAP1A | -384 |
| TRPM2 | -378 |
| CREG1 | -369 |
| OSTF1 | -354 |
| FCN1 | -340 |
| ARSA | -183 |
| GHDC | -167 |
| GUSB | -113 |
| PGM2 | -23 |
| PYGB | 19 |
| ALDOA | 25 |
| CNN2 | 183 |
| LAMTOR1 | 215 |
| VAMP8 | 328 |
| JUP | 465 |
| NHLRC3 | 611 |
| AGL | 667 |
| TMEM179B | 811 |
| SERPINB6 | 915 |
| RAB10 | 940 |
| ROCK1 | 965 |
| CEP290 | 1033 |
| PECAM1 | 1067 |
| PAFAH1B2 | 1161 |
| RAP2B | 1165 |
| GSTP1 | 1170 |
| AZU1 | 1191 |
| CYB5R3 | 1237 |
| PSMD6 | 1244 |
| STK11IP | 1266 |
| SDCBP | 1329 |
| XRCC6 | 1347 |
| MCEMP1 | 1408 |
| ATG7 | 1417 |
| HK3 | 1481 |
| ATP6V0C | 1512 |
| VAPA | 1513 |
| IQGAP1 | 1557 |
| SELL | 1560 |
| PTPRN2 | 1564 |
| ITGAX | 1566 |
| VPS35L | 1567 |
| HLA-A | 1643 |
| HGSNAT | 1665 |
| CXCR2 | 1666 |
| HSPA8 | 1683 |
| FAF2 | 1719 |
| CYFIP1 | 1733 |
| PPIA | 1750 |
| CD44 | 1832 |
| SPTAN1 | 1882 |
| RAB14 | 1952 |
| HLA-C | 2005 |
| CST3 | 2013 |
| PDXK | 2151 |
| CTSS | 2170 |
| SNAP29 | 2184 |
| ANO6 | 2222 |
| RAB4B | 2243 |
| ITGAM | 2304 |
| CTSA | 2375 |
| SERPINB1 | 2512 |
| PSMA5 | 2542 |
| QSOX1 | 2616 |
| ATP11B | 2635 |
| FRK | 2713 |
| TNFRSF1B | 2797 |
| MME | 2873 |
| LPCAT1 | 2901 |
| PGAM1 | 2941 |
| CAPN1 | 2973 |
| NDUFC2 | 3031 |
| S100A11 | 3059 |
| PGM1 | 3074 |
| ITGAV | 3093 |
| ARPC5 | 3103 |
| CAP1 | 3198 |
| CRACR2A | 3212 |
| CPNE1 | 3300 |
| PSMD2 | 3383 |
| RAB5C | 3602 |
| VCL | 3647 |
| MAN2B1 | 3662 |
| ACLY | 3821 |
| FCGR2A | 3837 |
| HEXB | 3888 |
| C3 | 3889 |
| BRI3 | 3964 |
| RAB5B | 4015 |
| ARSB | 4029 |
| DPP7 | 4062 |
| CALML5 | 4110 |
| ERP44 | 4123 |
| TCIRG1 | 4135 |
| CTSB | 4194 |
| KCNAB2 | 4244 |
| TNFAIP6 | 4255 |
| ANXA2 | 4374 |
| KRT1 | 4388 |
| HBB | 4410 |
| GAA | 4446 |
| CD58 | 4480 |
| TICAM2 | 4515 |
| LAMTOR3 | 4577 |
| ADAM8 | 4598 |
| RAB24 | 4624 |
| IGF2R | 4652 |
| RHOA | 4928 |
| GLB1 | 4936 |
| CD14 | 5065 |
| LAIR1 | 5189 |
| IQGAP2 | 5324 |
| AGA | 5326 |
| SNAP23 | 5360 |
| IMPDH1 | 5488 |
| PSMD7 | 5490 |
| VCP | 5713 |
| DSP | 5721 |
| TRAPPC1 | 5725 |
| C6orf120 | 5727 |
| SERPINB3 | 5770 |
| FLG2 | 5773 |
| TXNDC5 | 5786 |
| PFKL | 5851 |
| APEH | 5853 |
| PTGES2 | 5866 |
| SVIP | 5951 |
| CAB39 | 5988 |
| COPB1 | 5990 |
| ARG1 | 6006 |
| GGH | 6079 |
| AP2A2 | 6101 |
| EEF2 | 6286 |
| NEU1 | 6335 |
| ORM2 | 6384 |
| DNAJC13 | 6440 |
| DSC1 | 6497 |
| DNAJC5 | 6570 |
| DYNC1H1 | 6590 |
| GALNS | 6649 |
| GPI | 6696 |
| TOLLIP | 6727 |
| ADA2 | 6759 |
| ATP8B4 | 6780 |
| ACAA1 | 6816 |
| CPPED1 | 6870 |
| TLR2 | 7026 |
| CCT2 | 7076 |
| CANT1 | 7122 |
| TCN1 | 7348 |
| ATAD3B | 7374 |
| ATP11A | 7460 |
| NIT2 | 7562 |
| CXCL1 | 7640 |
| SLCO4C1 | 7669 |
| FUCA2 | 7735 |
| ALAD | 7841 |
| PPIE | 7929 |
| FPR1 | 7940 |
| COMMD3 | 7946 |
| LGALS3 | 8154 |
| SIGLEC5 | 8257 |
| MMP8 | 8345 |
| SIRPB1 | 8404 |
| AP1M1 | 8630 |
| LAMP1 | 8730 |
| C3AR1 | 8829 |
| HRNR | 8850 |
| RETN | 8884 |
REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION
| 1161 | |
|---|---|
| set | REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION |
| setSize | 1336 |
| pANOVA | 4.38e-05 |
| s.dist | 0.0666 |
| p.adjustANOVA | 0.024 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| ZNF717 | 9544 |
| GP1BA | 9464 |
| ZNF738 | 9454 |
| ZNF286A | 9379 |
| POLR2J | 9345 |
| SNAPC4 | 9344 |
| KMT2B | 9303 |
| ZNF587 | 9298 |
| AGRP | 9275 |
| MED30 | 9271 |
| ZNF471 | 9259 |
| ZNF300 | 9248 |
| ZNF761 | 9243 |
| ZNF439 | 9199 |
| CGB5 | 9176 |
| ZNF492 | 9160 |
| ZNF558 | 9159 |
| ZFP28 | 9147 |
| ZNF431 | 9122 |
| MIR24-1 | 9041 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ZNF717 | 9544.0 |
| GP1BA | 9464.0 |
| ZNF738 | 9454.0 |
| ZNF286A | 9379.0 |
| POLR2J | 9345.0 |
| SNAPC4 | 9344.0 |
| KMT2B | 9303.0 |
| ZNF587 | 9298.0 |
| AGRP | 9275.0 |
| MED30 | 9271.0 |
| ZNF471 | 9259.0 |
| ZNF300 | 9248.0 |
| ZNF761 | 9243.0 |
| ZNF439 | 9199.0 |
| CGB5 | 9176.0 |
| ZNF492 | 9160.0 |
| ZNF558 | 9159.0 |
| ZFP28 | 9147.0 |
| ZNF431 | 9122.0 |
| MIR24-1 | 9041.0 |
| ZNF667 | 9016.0 |
| ZNF699 | 8961.0 |
| HDAC1 | 8951.0 |
| ZNF383 | 8946.0 |
| PHC1 | 8944.0 |
| ZNF347 | 8930.0 |
| ZNF626 | 8920.0 |
| NELFB | 8897.0 |
| ZNF750 | 8889.0 |
| RETN | 8884.0 |
| CBX6 | 8883.0 |
| H2BC15 | 8813.0 |
| NPPA | 8804.0 |
| WDR5 | 8800.0 |
| ZNF124 | 8791.0 |
| ZNF302 | 8789.0 |
| IL2 | 8751.0 |
| BMP2 | 8725.0 |
| RELA | 8703.0 |
| SIN3B | 8658.0 |
| ZNF736 | 8645.0 |
| ZNF135 | 8627.0 |
| BIRC5 | 8613.0 |
| ZNF785 | 8582.0 |
| TCF3 | 8579.0 |
| THOC3 | 8555.0 |
| ZNF625 | 8551.0 |
| ZNF417 | 8525.0 |
| ZNF222 | 8505.0 |
| SNAPC1 | 8476.0 |
| ZNF114 | 8473.0 |
| ZNF169 | 8453.0 |
| PIDD1 | 8441.0 |
| ZNF624 | 8414.0 |
| ZNF701 | 8412.0 |
| INTS1 | 8376.0 |
| TSC2 | 8343.0 |
| ZNF665 | 8336.0 |
| CSF2 | 8329.0 |
| TACO1 | 8292.0 |
| NR2E3 | 8209.0 |
| PSMA8 | 8189.0 |
| ANAPC1 | 8165.0 |
| ZNF714 | 8163.0 |
| ZNF662 | 8158.0 |
| LGALS3 | 8154.0 |
| PRDX1 | 8150.0 |
| ZNF493 | 8139.0 |
| CASP10 | 8135.0 |
| ANAPC2 | 8132.0 |
| BANP | 8129.0 |
| ZFP2 | 8128.0 |
| HEY2 | 8091.0 |
| ZNF681 | 8084.0 |
| ZNF14 | 8056.0 |
| POLR2A | 8039.0 |
| RORC | 8014.0 |
| ZIK1 | 8010.0 |
| KAT2B | 8009.0 |
| SERPINE1 | 8005.0 |
| PCGF2 | 7999.0 |
| SMARCB1 | 7996.0 |
| ZNF214 | 7979.0 |
| CASP2 | 7942.0 |
| ZNF74 | 7925.0 |
| ZNF675 | 7898.0 |
| ZNF793 | 7893.0 |
| RB1 | 7884.0 |
| SRSF5 | 7818.0 |
| ZNF45 | 7808.0 |
| ZNF486 | 7795.0 |
| ZNF442 | 7775.0 |
| THBS1 | 7766.0 |
| SETD1A | 7757.0 |
| ZNF226 | 7755.0 |
| MLLT1 | 7749.0 |
| TAF4 | 7742.0 |
| ZNF724 | 7715.0 |
| BRCA1 | 7712.0 |
| NOTCH1 | 7710.0 |
| ZNF519 | 7704.0 |
| ZNF433 | 7689.0 |
| BGLAP | 7676.0 |
| PRKAA2 | 7672.0 |
| ZNF615 | 7662.0 |
| ZNF737 | 7647.0 |
| CDC23 | 7628.0 |
| H3C3 | 7600.0 |
| PIP4K2B | 7570.0 |
| SREBF1 | 7540.0 |
| SLU7 | 7532.0 |
| ING5 | 7528.0 |
| EHMT1 | 7514.0 |
| TNFRSF10C | 7512.0 |
| ERCC3 | 7495.0 |
| ZNF607 | 7480.0 |
| ZNF317 | 7474.0 |
| AKT1 | 7464.0 |
| ZNF418 | 7447.0 |
| YWHAB | 7438.0 |
| AIFM2 | 7434.0 |
| ZNF549 | 7430.0 |
| ACTL6B | 7401.0 |
| POU4F2 | 7342.0 |
| PLK2 | 7339.0 |
| ZNF589 | 7335.0 |
| NR0B2 | 7323.0 |
| SOCS4 | 7305.0 |
| AXIN1 | 7283.0 |
| ZNF12 | 7268.0 |
| EHMT2 | 7237.0 |
| SMAD3 | 7232.0 |
| ZNF416 | 7206.0 |
| TAL1 | 7194.0 |
| CITED4 | 7164.0 |
| ZNF208 | 7157.0 |
| MED7 | 7150.0 |
| FURIN | 7145.0 |
| E2F6 | 7130.0 |
| ZNF223 | 7128.0 |
| H2AX | 7107.0 |
| GPX2 | 7098.0 |
| CREB1 | 7072.0 |
| HTT | 7054.0 |
| MED16 | 7052.0 |
| CCNA2 | 7041.0 |
| NPY | 7005.0 |
| CBX2 | 6998.0 |
| H2BC9 | 6991.5 |
| H3C7 | 6991.5 |
| ZNF285 | 6982.0 |
| ZNF664 | 6964.0 |
| ZNF804B | 6962.0 |
| ZFPM1 | 6960.0 |
| NR1D2 | 6957.0 |
| PABPN1 | 6939.0 |
| SMURF1 | 6933.0 |
| TMEM219 | 6907.0 |
| ZNF773 | 6900.0 |
| ZKSCAN4 | 6899.0 |
| ZNF426 | 6869.0 |
| SRRT | 6852.0 |
| CNOT6 | 6801.0 |
| FOXG1 | 6797.0 |
| ZNF470 | 6790.0 |
| BRPF1 | 6789.0 |
| CHD3 | 6769.0 |
| MIR24-2 | 6760.0 |
| ZNF263 | 6741.0 |
| RPTOR | 6730.0 |
| GPI | 6696.0 |
| MIR27A | 6694.0 |
| KLF4 | 6687.0 |
| GTF2B | 6661.0 |
| GATA2 | 6658.0 |
| ZNF777 | 6651.0 |
| STK11 | 6647.0 |
| ZNF564 | 6646.0 |
| THOC7 | 6633.0 |
| ZNF764 | 6627.0 |
| SCMH1 | 6613.0 |
| MED10 | 6606.0 |
| ELL2 | 6597.0 |
| H4C13 | 6594.0 |
| ZNF782 | 6577.0 |
| ZNF689 | 6568.0 |
| ZNF160 | 6556.0 |
| DGCR8 | 6537.0 |
| PRELID3A | 6519.0 |
| RAD9A | 6488.0 |
| CCN2 | 6487.0 |
| KMT2D | 6479.0 |
| ZNF33B | 6471.0 |
| YY1 | 6457.0 |
| NR1H2 | 6444.0 |
| HDAC2 | 6411.0 |
| FZR1 | 6385.0 |
| TFDP1 | 6381.0 |
| SIRT1 | 6379.0 |
| PARP1 | 6374.0 |
| ZFP14 | 6358.0 |
| PSMF1 | 6349.0 |
| TAF4B | 6330.0 |
| KMT2C | 6289.0 |
| MTOR | 6285.0 |
| ZNF100 | 6250.0 |
| ZNF597 | 6247.0 |
| SMAD4 | 6230.0 |
| ZNF729 | 6229.0 |
| ZNF669 | 6224.0 |
| H4C11 | 6170.0 |
| ZNF112 | 6150.0 |
| H4C16 | 6148.0 |
| ZNF562 | 6138.0 |
| ZNF354B | 6093.0 |
| PRKAG3 | 6061.0 |
| AKT2 | 6057.0 |
| ZNF441 | 6054.0 |
| MLLT3 | 6043.0 |
| GEM | 6041.0 |
| COX16 | 6040.0 |
| ZNF425 | 6034.0 |
| ZNF264 | 6031.0 |
| SRSF4 | 6012.0 |
| NCOR2 | 6009.0 |
| GTF2H4 | 6008.0 |
| PLK3 | 6005.0 |
| ZNF430 | 5957.0 |
| ZNF43 | 5885.0 |
| ATF2 | 5884.0 |
| PTPN4 | 5859.0 |
| MNAT1 | 5835.0 |
| SRSF11 | 5810.0 |
| HUS1 | 5797.0 |
| DHX38 | 5783.0 |
| ZNF454 | 5766.0 |
| ZNF436 | 5750.0 |
| BRPF3 | 5709.0 |
| BMI1 | 5690.0 |
| ZNF354C | 5676.0 |
| AGO2 | 5651.0 |
| SOX9 | 5642.0 |
| CDK12 | 5627.0 |
| MAPKAP1 | 5598.0 |
| ZNF613 | 5578.0 |
| CASP1 | 5568.0 |
| MSH2 | 5564.0 |
| CRH | 5559.0 |
| NRBP1 | 5543.0 |
| TFDP2 | 5529.0 |
| CARM1 | 5520.0 |
| H4C4 | 5517.0 |
| ZNF211 | 5507.0 |
| PSMD7 | 5490.0 |
| ANAPC4 | 5471.0 |
| TAF2 | 5439.0 |
| TFAP2D | 5417.0 |
| CPSF3 | 5393.0 |
| TAF1L | 5385.0 |
| H4C3 | 5331.0 |
| DPY30 | 5310.0 |
| NR2C2 | 5285.0 |
| CDC73 | 5279.0 |
| ZNF227 | 5236.0 |
| ZNF792 | 5232.0 |
| HDAC4 | 5193.0 |
| INTS4 | 5183.0 |
| KRBA1 | 5154.0 |
| MDC1 | 5118.0 |
| OPRK1 | 5112.0 |
| THOC6 | 5093.0 |
| PRKAB1 | 5077.0 |
| CPSF7 | 5076.0 |
| MLH1 | 5071.0 |
| NR5A1 | 5061.0 |
| NFYC | 5059.0 |
| PSMC1 | 5036.0 |
| RRM2 | 5030.0 |
| MBD3 | 5014.0 |
| BMAL1 | 4992.0 |
| RPA1 | 4991.0 |
| CNOT3 | 4962.0 |
| TNRC6A | 4958.0 |
| PDPK1 | 4953.0 |
| ARID1B | 4919.0 |
| TBL1XR1 | 4893.0 |
| ZSCAN25 | 4874.0 |
| ZNF521 | 4857.0 |
| ZNF496 | 4841.0 |
| ZNF556 | 4806.0 |
| GAMT | 4802.0 |
| ZNF311 | 4790.0 |
| ELF2 | 4788.0 |
| ZNF600 | 4762.0 |
| KRBOX5 | 4755.0 |
| PPARGC1A | 4753.0 |
| H3C10 | 4749.0 |
| PLAGL1 | 4742.0 |
| PHF20 | 4738.0 |
| AFF4 | 4718.0 |
| TJP1 | 4706.0 |
| RUNX2 | 4682.0 |
| ZNF585B | 4659.0 |
| MEN1 | 4643.0 |
| ATAD2 | 4642.0 |
| ZNF267 | 4629.0 |
| GTF2F1 | 4591.0 |
| ALYREF | 4582.0 |
| LAMTOR3 | 4577.0 |
| PRMT5 | 4533.0 |
| CASC3 | 4491.0 |
| ZFP69 | 4483.0 |
| CDK8 | 4461.0 |
| H2AC4 | 4441.0 |
| RAD9B | 4435.0 |
| DNA2 | 4434.0 |
| CNOT1 | 4430.0 |
| ZSCAN32 | 4429.0 |
| AGO3 | 4409.0 |
| ZNF213 | 4386.0 |
| UBA52 | 4371.0 |
| ZNF136 | 4361.0 |
| ZNF479 | 4347.0 |
| RNPS1 | 4327.0 |
| GTF2F2 | 4313.0 |
| INTS9 | 4306.0 |
| TP53 | 4288.0 |
| RORA | 4281.0 |
| SMAD2 | 4260.0 |
| CLP1 | 4258.0 |
| SUPT6H | 4253.0 |
| TP53INP1 | 4250.0 |
| UBE2I | 4247.0 |
| SSU72 | 4231.0 |
| SUZ12 | 4220.0 |
| STAT1 | 4195.0 |
| ZNF627 | 4186.0 |
| ASH2L | 4178.0 |
| ZNF726 | 4152.0 |
| ZNF559 | 4141.0 |
| FANCC | 4140.0 |
| CALM1 | 4126.0 |
| ANAPC11 | 4125.0 |
| NBN | 4116.0 |
| MAF | 4109.0 |
| NELFA | 4099.0 |
| E2F7 | 4081.0 |
| YAF2 | 4076.0 |
| TAF7 | 4073.0 |
| ZNF234 | 4072.0 |
| PIN1 | 4069.0 |
| RXRB | 4038.0 |
| CTDP1 | 4026.0 |
| SATB2 | 4006.0 |
| ZNF530 | 3995.0 |
| ZNF253 | 3978.0 |
| TSC1 | 3972.0 |
| EP300 | 3970.0 |
| HDAC3 | 3966.0 |
| RING1 | 3961.0 |
| TIGAR | 3951.0 |
| ZNF544 | 3947.0 |
| RMI2 | 3946.0 |
| PGR | 3941.0 |
| JUN | 3936.0 |
| ZNF443 | 3920.0 |
| GSR | 3919.0 |
| ZNF33A | 3916.0 |
| ZNF256 | 3876.0 |
| SST | 3786.0 |
| ZNF799 | 3774.0 |
| CBX3 | 3764.0 |
| ANAPC10 | 3735.0 |
| ZNF138 | 3706.0 |
| ZNF611 | 3698.0 |
| MED13 | 3675.0 |
| MEF2C | 3665.0 |
| INTS6 | 3613.0 |
| ZNF605 | 3570.0 |
| ZNF563 | 3565.0 |
| RNGTT | 3528.0 |
| CDC16 | 3502.0 |
| COX6B1 | 3495.0 |
| MED27 | 3487.0 |
| RBL1 | 3482.0 |
| UBE2S | 3469.0 |
| TNKS1BP1 | 3466.0 |
| PSMC6 | 3448.0 |
| SUPT4H1 | 3447.0 |
| NKX3-2 | 3439.0 |
| IL6 | 3431.0 |
| ZNF696 | 3429.0 |
| SNAPC5 | 3410.0 |
| PSMD2 | 3383.0 |
| BRD1 | 3378.0 |
| INTS8 | 3368.0 |
| DEK | 3351.0 |
| ARID3A | 3346.0 |
| EIF4A3 | 3324.0 |
| ZNF3 | 3317.0 |
| RNF34 | 3301.0 |
| CPSF6 | 3290.0 |
| PRKAG2 | 3279.0 |
| RSPO3 | 3269.0 |
| COX14 | 3267.0 |
| GTF2H1 | 3263.0 |
| MAX | 3258.0 |
| U2AF2 | 3254.0 |
| CEBPB | 3224.0 |
| CCNA1 | 3223.0 |
| NELFE | 3207.0 |
| SMAD1 | 3199.0 |
| ZNF266 | 3189.0 |
| ELOC | 3168.0 |
| FOXO3 | 3150.0 |
| CHD4 | 3141.0 |
| ZNF331 | 3131.0 |
| THOC5 | 3124.0 |
| CCNT1 | 3115.0 |
| GPAM | 3105.0 |
| GLI3 | 3053.0 |
| COX5B | 3048.0 |
| MED23 | 3037.0 |
| PRELID1 | 3027.0 |
| ATR | 3006.0 |
| RABGGTA | 2993.0 |
| ZNF419 | 2983.0 |
| LAMTOR4 | 2978.0 |
| ZNF577 | 2977.0 |
| PF4 | 2971.0 |
| INTS11 | 2969.0 |
| H2BC12 | 2936.0 |
| CNOT8 | 2934.0 |
| TCF12 | 2918.0 |
| SLC38A9 | 2917.0 |
| CCNC | 2913.0 |
| PRKCB | 2908.0 |
| YES1 | 2889.0 |
| CCNK | 2859.0 |
| CTSK | 2842.0 |
| BRIP1 | 2839.0 |
| ZC3H8 | 2822.0 |
| ZNF570 | 2818.0 |
| CUL1 | 2803.0 |
| ZNF197 | 2798.0 |
| HEY1 | 2759.0 |
| SNRPF | 2753.0 |
| GLS | 2736.0 |
| OPRM1 | 2735.0 |
| FOXO1 | 2723.0 |
| ARNT | 2714.0 |
| PSMB6 | 2700.0 |
| GATA3 | 2644.0 |
| PSME1 | 2636.0 |
| RBFOX1 | 2632.0 |
| POLR2B | 2622.0 |
| DLL1 | 2610.0 |
| SMARCA4 | 2567.0 |
| ZNF324B | 2560.0 |
| SSRP1 | 2555.0 |
| BRD7 | 2550.0 |
| PSMA5 | 2542.0 |
| CTNNB1 | 2534.0 |
| SNRPB | 2533.0 |
| RNMT | 2531.0 |
| ACTL6A | 2529.0 |
| ZNF775 | 2495.0 |
| RBBP8 | 2493.0 |
| ZNF133 | 2419.0 |
| RHNO1 | 2378.0 |
| ZNF713 | 2357.0 |
| UBE2D1 | 2345.0 |
| KAT6A | 2327.0 |
| ZNF248 | 2292.0 |
| ZNF141 | 2265.0 |
| ZNF215 | 2232.0 |
| ZNF324 | 2223.0 |
| ZNF875 | 2217.0 |
| MOV10 | 2211.0 |
| TCF7L2 | 2208.0 |
| PTPN11 | 2193.0 |
| AKT3 | 2190.0 |
| SESN1 | 2188.0 |
| ZNF18 | 2169.0 |
| E2F4 | 2119.0 |
| ZNF510 | 2093.0 |
| NCOR1 | 2075.0 |
| PSMB2 | 2057.0 |
| CNOT7 | 2036.0 |
| ZIM3 | 2033.0 |
| H4C12 | 1999.0 |
| TNRC6B | 1978.0 |
| ZNF394 | 1973.0 |
| AUTS2 | 1972.0 |
| SEM1 | 1961.0 |
| SETD1B | 1886.0 |
| CREBBP | 1880.0 |
| ESR1 | 1879.0 |
| PPP2R1B | 1865.0 |
| ZNF445 | 1857.0 |
| PPP2R5C | 1854.0 |
| BDNF | 1830.0 |
| PRMT1 | 1824.0 |
| IL3 | 1821.0 |
| NOC2L | 1800.0 |
| CBFB | 1784.0 |
| INS | 1760.0 |
| CAMK2G | 1746.0 |
| SURF1 | 1740.0 |
| H2BC8 | 1727.0 |
| IHH | 1726.0 |
| ZNF517 | 1712.0 |
| PPP2CA | 1705.0 |
| POLR2G | 1673.0 |
| ZNF557 | 1634.0 |
| RFC5 | 1629.0 |
| PSME3 | 1619.0 |
| WRN | 1603.0 |
| MYBL2 | 1587.0 |
| WWP1 | 1584.0 |
| TAF3 | 1577.0 |
| NR1D1 | 1555.0 |
| ZNF554 | 1545.0 |
| E2F8 | 1543.0 |
| INTS2 | 1538.0 |
| PRKAA1 | 1528.0 |
| ZIM2 | 1519.0 |
| NABP1 | 1457.0 |
| RMI1 | 1440.0 |
| CNOT9 | 1414.0 |
| ZFP30 | 1411.0 |
| RABGGTB | 1393.0 |
| ZNF195 | 1384.0 |
| ZKSCAN7 | 1361.0 |
| CCNE2 | 1330.0 |
| HDAC5 | 1328.0 |
| SGK1 | 1327.0 |
| TRIM33 | 1307.0 |
| H2AC18 | 1298.5 |
| H2AC19 | 1298.5 |
| FIP1L1 | 1293.0 |
| MED17 | 1290.0 |
| ZNF778 | 1276.0 |
| SCO1 | 1251.0 |
| PSMD6 | 1244.0 |
| ZNF678 | 1242.0 |
| SRSF1 | 1241.0 |
| SMARCD2 | 1183.0 |
| MAPK3 | 1159.0 |
| ZNF584 | 1156.0 |
| MAPKAPK5 | 1151.0 |
| ZNF26 | 1138.0 |
| CAMK2D | 1121.0 |
| SYMPK | 1084.0 |
| H2BC10 | 1052.0 |
| LAMTOR5 | 1049.0 |
| ITGA2B | 1047.0 |
| TGFA | 1018.0 |
| GADD45A | 1005.0 |
| FANCI | 977.0 |
| PAPOLA | 972.0 |
| ZNF189 | 961.0 |
| ZNF343 | 958.0 |
| TP53AIP1 | 928.0 |
| KCNIP3 | 923.0 |
| ZNF468 | 910.0 |
| LMO1 | 897.0 |
| PCGF5 | 888.0 |
| PAF1 | 885.0 |
| TOP3A | 882.0 |
| CNOT2 | 837.0 |
| INTS14 | 834.0 |
| KCTD6 | 824.0 |
| PCNA | 815.0 |
| TP63 | 810.0 |
| ZNF200 | 801.0 |
| ZNF282 | 768.0 |
| PSMA3 | 761.0 |
| POLR2H | 760.0 |
| EGFR | 756.0 |
| SKIL | 726.0 |
| POLR2F | 722.0 |
| COL1A2 | 720.0 |
| ZNF774 | 697.0 |
| FKBP5 | 693.0 |
| HIVEP3 | 691.0 |
| POU2F2 | 685.0 |
| EED | 676.0 |
| CBX5 | 643.0 |
| TGFB1 | 605.0 |
| ZNF684 | 592.0 |
| ZNF202 | 576.0 |
| CCNG1 | 553.0 |
| PPARA | 540.0 |
| TGIF1 | 533.0 |
| RARA | 519.0 |
| LEO1 | 514.0 |
| GAD1 | 501.0 |
| HDAC11 | 487.0 |
| ING2 | 474.0 |
| ATM | 437.0 |
| CDKN1B | 426.0 |
| SOD2 | 399.0 |
| TXNIP | 376.0 |
| NR3C1 | 344.0 |
| HDAC10 | 340.0 |
| RRAGA | 333.0 |
| ZNF721 | 329.0 |
| POLR2D | 313.0 |
| RNF111 | 286.0 |
| TXN | 273.0 |
| TRIM28 | 263.0 |
| SMARCC2 | 254.0 |
| DDIT4 | 242.0 |
| LAMTOR1 | 215.0 |
| RPRD1A | 195.0 |
| ZNF304 | 189.0 |
| CDC27 | 181.0 |
| ZNF680 | 173.0 |
| ATXN3 | 149.0 |
| ZNF30 | 146.0 |
| SKI | 136.0 |
| RBPJ | 129.0 |
| HDAC7 | 107.0 |
| KRAS | 94.0 |
| PRMT6 | 87.0 |
| PIP4K2C | 85.0 |
| IFNG | 78.0 |
| ZNF740 | 69.0 |
| PSMD5 | 47.0 |
| STUB1 | 28.0 |
| ZKSCAN5 | 23.0 |
| RBFOX3 | 3.0 |
| TNFRSF10D | -22.0 |
| RUNX1 | -31.0 |
| GRIA2 | -76.0 |
| HDAC9 | -105.0 |
| RRM2B | -107.0 |
| SMARCD1 | -118.0 |
| CENPJ | -126.0 |
| INTS10 | -142.0 |
| H3C8 | -157.0 |
| RHEB | -181.0 |
| RICTOR | -193.0 |
| TAF12 | -200.0 |
| PTPN1 | -211.0 |
| ZFP37 | -221.0 |
| THOC1 | -228.0 |
| ZNF17 | -244.0 |
| ZNF555 | -288.0 |
| ZNF273 | -289.0 |
| ZNF569 | -299.0 |
| MAP2K6 | -317.0 |
| PCBP4 | -332.0 |
| GLS2 | -335.0 |
| H2BC13 | -344.0 |
| PPP1R13B | -355.0 |
| PRKAG1 | -424.0 |
| GTF2E2 | -429.0 |
| KAT5 | -454.0 |
| TEAD4 | -495.0 |
| RFC3 | -509.0 |
| ZNF583 | -522.0 |
| SNW1 | -525.0 |
| SYT10 | -568.0 |
| NFYB | -575.0 |
| GTF2A2 | -582.0 |
| MED24 | -599.0 |
| SMAD6 | -603.0 |
| RNF2 | -618.0 |
| POU2F1 | -635.0 |
| GRIN2A | -642.0 |
| CPSF1 | -650.0 |
| ZNF709 | -667.0 |
| CPSF4 | -693.0 |
| ZNF552 | -696.0 |
| ELL | -697.0 |
| SUPT5H | -750.0 |
| BCL2L14 | -754.0 |
| MED1 | -765.0 |
| LEF1 | -784.0 |
| ZNF550 | -791.0 |
| MEAF6 | -812.0 |
| CCND1 | -813.0 |
| ITCH | -817.0 |
| ZNF233 | -827.0 |
| MED31 | -830.0 |
| H3C11 | -834.0 |
| LAMTOR2 | -845.0 |
| MLST8 | -872.0 |
| YWHAE | -881.0 |
| CDC26 | -919.0 |
| BRD2 | -920.0 |
| TEAD2 | -936.0 |
| CSTF2T | -951.0 |
| KMT5A | -954.0 |
| PSMD14 | -968.0 |
| CNOT10 | -988.0 |
| PML | -996.0 |
| HIPK2 | -1007.0 |
| PCGF6 | -1010.0 |
| SMARCC1 | -1057.0 |
| ZNF79 | -1058.0 |
| IGFBP3 | -1070.0 |
| MDM2 | -1112.0 |
| ZNF776 | -1119.0 |
| ZNF772 | -1127.0 |
| H2AC6 | -1218.0 |
| NR3C2 | -1226.0 |
| PRDM1 | -1228.0 |
| ZNF716 | -1243.0 |
| TP53BP2 | -1252.0 |
| DAXX | -1259.0 |
| SP1 | -1277.0 |
| IWS1 | -1280.0 |
| CCND3 | -1286.0 |
| ZNF490 | -1293.0 |
| NPAS4 | -1295.0 |
| H3C2 | -1304.0 |
| ERCC2 | -1316.0 |
| CCND2 | -1329.0 |
| CDC40 | -1342.0 |
| ZNF99 | -1358.0 |
| GAD2 | -1377.0 |
| ZNF28 | -1380.0 |
| FYTTD1 | -1381.0 |
| ESRRA | -1399.0 |
| GTF2A1 | -1429.0 |
| THRB | -1450.0 |
| H3-3A | -1455.0 |
| RPRD2 | -1456.0 |
| RBL2 | -1480.0 |
| L3MBTL2 | -1490.0 |
| TBX5 | -1498.0 |
| DLX5 | -1507.0 |
| BCL2L11 | -1510.0 |
| ZNF480 | -1519.0 |
| ZNF500 | -1536.0 |
| LRPPRC | -1557.0 |
| ZNF461 | -1603.0 |
| KDM5B | -1637.0 |
| STEAP3 | -1673.0 |
| PPM1D | -1681.0 |
| MAPK1 | -1683.0 |
| ZNF700 | -1685.0 |
| POU4F1 | -1714.0 |
| ZNF333 | -1715.0 |
| WWTR1 | -1718.0 |
| E2F5 | -1719.0 |
| RXRA | -1749.0 |
| H2AC8 | -1791.0 |
| ZNF749 | -1796.0 |
| GATAD2B | -1799.0 |
| ARID2 | -1828.0 |
| CAMK2B | -1887.0 |
| CNOT11 | -1890.0 |
| SMYD2 | -1898.0 |
| SOX2 | -1935.0 |
| TFAP2A | -1948.0 |
| ZNF707 | -1955.0 |
| ZNF484 | -1986.0 |
| SARNP | -2010.0 |
| INTS3 | -2028.0 |
| MED25 | -2048.0 |
| UBE2E1 | -2139.0 |
| SMAD7 | -2147.0 |
| ZNF679 | -2170.0 |
| PSMD1 | -2198.0 |
| H2BC21 | -2245.0 |
| JMY | -2263.0 |
| DLX6 | -2295.0 |
| COX7C | -2313.0 |
| PCK1 | -2327.0 |
| MED4 | -2347.0 |
| ZNF140 | -2350.0 |
| ZNF268 | -2361.0 |
| RFFL | -2399.0 |
| H3C6 | -2432.0 |
| SIN3A | -2444.0 |
| ZNF70 | -2448.0 |
| ANAPC7 | -2456.0 |
| GPRIN1 | -2465.0 |
| H4C2 | -2471.0 |
| NR1H3 | -2472.0 |
| ZNF225 | -2477.0 |
| TNFRSF10A | -2483.0 |
| ATRIP | -2487.0 |
| SESN2 | -2490.0 |
| H4C9 | -2491.0 |
| ZNF257 | -2493.0 |
| ARID1A | -2498.0 |
| ZNF398 | -2519.0 |
| EXO1 | -2529.0 |
| ZNF560 | -2538.0 |
| INTS12 | -2544.0 |
| CDC7 | -2601.0 |
| CBX8 | -2612.0 |
| COX7A2L | -2617.0 |
| KAT2A | -2622.0 |
| EAF2 | -2645.0 |
| PBRM1 | -2651.0 |
| ELOB | -2654.0 |
| SRRM1 | -2663.0 |
| PSMD9 | -2679.0 |
| MTA2 | -2680.0 |
| ZNF528 | -2687.0 |
| CDK5R1 | -2738.0 |
| PHC2 | -2749.0 |
| TFAP2E | -2767.0 |
| MOBP | -2782.0 |
| LBR | -2792.0 |
| ZNF770 | -2808.0 |
| PRKCQ | -2828.0 |
| PCF11 | -2835.0 |
| PRR5 | -2836.0 |
| INTS5 | -2842.0 |
| APOE | -2860.0 |
| FBXO32 | -2872.0 |
| ZKSCAN3 | -2902.0 |
| LSM11 | -2906.0 |
| ZNF655 | -2931.0 |
| POLR2K | -2963.0 |
| CTLA4 | -2965.0 |
| FBXW7 | -2993.0 |
| PSMD8 | -3004.0 |
| ZNF175 | -3016.0 |
| PTEN | -3066.0 |
| LIFR | -3071.0 |
| ZNF561 | -3093.0 |
| ZNF567 | -3123.0 |
| ZNF599 | -3153.0 |
| KMT2E | -3178.0 |
| ZNF230 | -3202.0 |
| PERP | -3220.0 |
| ZFP1 | -3228.0 |
| PIP4P1 | -3230.0 |
| CDK2 | -3257.0 |
| ZNF619 | -3265.0 |
| NR2E1 | -3299.0 |
| LSM10 | -3305.0 |
| CDC25C | -3335.0 |
| H2AZ1 | -3348.0 |
| RAD51D | -3376.0 |
| BID | -3401.0 |
| CCNE1 | -3403.0 |
| NABP2 | -3434.0 |
| VEGFA | -3460.0 |
| PLXNA4 | -3466.0 |
| ZNF614 | -3488.0 |
| ZNF786 | -3492.0 |
| ZNF703 | -3498.0 |
| CNOT4 | -3502.0 |
| ZNF446 | -3505.0 |
| ZNF620 | -3549.0 |
| ABL1 | -3561.0 |
| ESRRB | -3571.0 |
| NOP2 | -3578.0 |
| ZNF735 | -3589.0 |
| TFAP2C | -3616.0 |
| NOTCH3 | -3647.0 |
| NPM1 | -3666.0 |
| RORB | -3675.0 |
| MAPK14 | -3702.0 |
| TWIST1 | -3710.0 |
| UBE2D3 | -3713.0 |
| TTC5 | -3717.0 |
| RBBP4 | -3719.0 |
| RPRD1B | -3726.0 |
| NFATC2 | -3728.0 |
| ZNF746 | -3763.0 |
| ZNF212 | -3781.0 |
| TGIF2 | -3782.0 |
| SMARCE1 | -3785.0 |
| ZNF250 | -3800.0 |
| ZNF25 | -3841.0 |
| SRSF6 | -3849.0 |
| JAG1 | -3857.0 |
| SETD9 | -3860.0 |
| CHTOP | -3867.0 |
| HSPD1 | -3873.0 |
| ZNF697 | -3875.0 |
| ZNF540 | -3906.0 |
| EAF1 | -3910.0 |
| NR5A2 | -3946.0 |
| RPAP2 | -3966.0 |
| GTF2H3 | -3987.0 |
| ESR2 | -4001.0 |
| WWOX | -4027.0 |
| SNRPG | -4037.0 |
| NR2F1 | -4056.0 |
| ZNF2 | -4101.0 |
| ZNF551 | -4115.0 |
| H2AJ | -4124.0 |
| CAT | -4127.0 |
| ANAPC5 | -4131.0 |
| CNOT6L | -4147.0 |
| HES1 | -4159.0 |
| TRPC3 | -4188.0 |
| PSMA6 | -4225.0 |
| AGO4 | -4233.0 |
| H2BC17 | -4265.0 |
| KCTD1 | -4281.0 |
| ZNF718 | -4289.0 |
| PSME4 | -4311.0 |
| CSNK2B | -4328.0 |
| CLDN5 | -4331.0 |
| COX4I1 | -4334.0 |
| HIPK1 | -4336.0 |
| CSF1R | -4341.0 |
| KCTD15 | -4347.0 |
| ZNF235 | -4350.0 |
| ZNF710 | -4353.0 |
| SMURF2 | -4354.0 |
| RAD17 | -4379.0 |
| YWHAZ | -4382.0 |
| PSMB10 | -4396.0 |
| POLDIP3 | -4420.0 |
| ZNF571 | -4422.0 |
| TNRC6C | -4434.0 |
| ZNF582 | -4439.0 |
| TP73 | -4444.0 |
| ITGAL | -4475.0 |
| RBBP5 | -4481.0 |
| TPX2 | -4482.0 |
| H2AC20 | -4507.0 |
| USP2 | -4522.0 |
| CCNH | -4547.0 |
| ZNF75A | -4553.0 |
| ZNF682 | -4571.0 |
| PRDX5 | -4589.0 |
| MYB | -4604.0 |
| TAF11 | -4623.0 |
| PPARG | -4640.0 |
| ELOA | -4685.0 |
| CDKN1A | -4689.0 |
| CTR9 | -4695.0 |
| NUAK1 | -4750.0 |
| IQSEC3 | -4768.0 |
| TOPBP1 | -4787.0 |
| BBC3 | -4790.0 |
| CDK7 | -4798.0 |
| TAF13 | -4803.0 |
| GSK3B | -4830.0 |
| CHEK1 | -4836.0 |
| ERBB2 | -4838.0 |
| TXNRD1 | -4872.0 |
| NEDD4L | -4879.0 |
| ITGBL1 | -4890.0 |
| ZNF506 | -4899.0 |
| PPARGC1B | -4906.0 |
| ZNF154 | -4910.0 |
| ZNF708 | -4925.0 |
| ZNF224 | -4958.0 |
| NCBP2 | -4990.0 |
| SNRPD3 | -5026.0 |
| MIR132 | -5033.0 |
| PSMA2 | -5037.0 |
| GCK | -5044.0 |
| SPP1 | -5077.0 |
| CTSV | -5082.0 |
| PSMB11 | -5123.0 |
| TNFRSF18 | -5137.0 |
| TRIAP1 | -5158.0 |
| ZNF771 | -5168.0 |
| INTS13 | -5184.0 |
| RYBP | -5191.0 |
| CAMK4 | -5199.0 |
| CDK1 | -5212.0 |
| DYRK2 | -5218.0 |
| SMARCA2 | -5222.0 |
| GPS2 | -5236.0 |
| NR1H4 | -5254.0 |
| H2BC4 | -5269.0 |
| PSMA4 | -5279.0 |
| YWHAQ | -5292.0 |
| CAV1 | -5299.0 |
| NR2F6 | -5327.0 |
| AURKB | -5330.0 |
| KMT2A | -5341.0 |
| ZNF71 | -5360.0 |
| CDKN2A | -5373.0 |
| BARD1 | -5377.0 |
| ZNF790 | -5396.0 |
| PPM1A | -5403.0 |
| RFC2 | -5440.0 |
| THRA | -5449.0 |
| PRKAB2 | -5450.0 |
| MYL9 | -5455.0 |
| EZH2 | -5457.0 |
| CPSF2 | -5461.0 |
| RNU4ATAC | -5469.0 |
| SNAPC2 | -5472.0 |
| USP7 | -5475.0 |
| NDUFA4 | -5487.0 |
| H4C5 | -5492.0 |
| GRIN2B | -5523.0 |
| MYC | -5550.0 |
| SLC2A3 | -5557.0 |
| ZNF546 | -5563.0 |
| PSMD3 | -5582.0 |
| ZNF610 | -5598.0 |
| H2BC26 | -5603.0 |
| ZNF143 | -5619.0 |
| MED20 | -5623.0 |
| ANAPC15 | -5689.0 |
| NFKB1 | -5696.0 |
| PAX5 | -5743.0 |
| U2AF1L4 | -5766.0 |
| CBX4 | -5767.0 |
| ZNF37A | -5774.0 |
| PSMA7 | -5784.0 |
| GATAD2A | -5799.0 |
| H2BC3 | -5808.0 |
| DDX39A | -5856.0 |
| MED6 | -5892.0 |
| ZNF596 | -5894.0 |
| TAF9 | -5899.0 |
| BLK | -5916.0 |
| CDK6 | -5918.0 |
| TAF8 | -5927.0 |
| HNF4A | -5931.0 |
| ZNF254 | -5932.0 |
| ITGA4 | -5941.0 |
| PSMB9 | -5962.0 |
| PRDM7 | -5985.0 |
| ZKSCAN1 | -5987.0 |
| PPP2CB | -5989.0 |
| YWHAG | -6009.0 |
| ZNF668 | -6021.0 |
| CRADD | -6070.0 |
| IL2RA | -6074.0 |
| PSMB5 | -6101.0 |
| ESRRG | -6139.0 |
| PINK1 | -6156.0 |
| TP53I3 | -6166.0 |
| ELF1 | -6190.0 |
| RBM8A | -6194.0 |
| ZNF337 | -6201.0 |
| ZNF606 | -6219.0 |
| PIP4K2A | -6221.0 |
| IGFBP1 | -6237.0 |
| ZC3H11A | -6257.0 |
| ZNF432 | -6273.0 |
| CGA | -6284.0 |
| NR2C2AP | -6288.0 |
| PITX2 | -6296.0 |
| ZNF670 | -6357.0 |
| SNAPC3 | -6366.0 |
| MGA | -6374.0 |
| COX6A1 | -6421.0 |
| COX11 | -6451.0 |
| ZNF616 | -6457.0 |
| NR6A1 | -6469.0 |
| PSMD4 | -6474.0 |
| RBX1 | -6489.0 |
| UBE2C | -6545.0 |
| NR4A1 | -6546.0 |
| BNIP3L | -6548.0 |
| UBB | -6558.0 |
| SOCS3 | -6561.0 |
| TEAD1 | -6640.0 |
| PHC3 | -6665.0 |
| RPA3 | -6683.0 |
| RET | -6690.0 |
| ZNF485 | -6704.0 |
| H2BC5 | -6716.0 |
| WDR33 | -6720.0 |
| CTSL | -6722.0 |
| NOTCH4 | -6741.0 |
| COX6C | -6746.0 |
| ZNF660 | -6751.0 |
| BLM | -6759.0 |
| MRE11 | -6761.0 |
| ZNF20 | -6765.0 |
| ZNF691 | -6790.0 |
| NAMPT | -6793.0 |
| COX19 | -6810.0 |
| MAPK11 | -6815.0 |
| ZNF23 | -6878.0 |
| FAS | -6895.0 |
| TNFRSF10B | -6896.0 |
| PPP2R1A | -6897.0 |
| ZNF747 | -6904.0 |
| RXRG | -6941.0 |
| NR4A2 | -6959.0 |
| H2BC1 | -7004.0 |
| RRAGD | -7024.0 |
| CSNK2A1 | -7031.0 |
| SKP2 | -7047.0 |
| INTS7 | -7069.0 |
| POLR2I | -7081.0 |
| APAF1 | -7090.0 |
| SFN | -7102.0 |
| BAX | -7108.0 |
| ZNF350 | -7119.0 |
| CCNG2 | -7168.0 |
| PSMA1 | -7186.0 |
| ZKSCAN8 | -7187.0 |
| ZNF791 | -7198.0 |
| PMS2 | -7233.0 |
| ZNF473 | -7295.0 |
| PPARD | -7303.0 |
| MAGOH | -7338.0 |
| EPC1 | -7342.0 |
| MED15 | -7351.0 |
| ZFP90 | -7354.0 |
| CASP6 | -7368.0 |
| GATA4 | -7404.0 |
| CCNT2 | -7406.0 |
| H2AZ2 | -7419.0 |
| TCEA1 | -7470.0 |
| ZNF621 | -7476.0 |
| SPI1 | -7492.0 |
| SKP1 | -7505.0 |
| UBC | -7516.0 |
| ZNF205 | -7519.0 |
| RRAGC | -7535.0 |
| TWIST2 | -7540.0 |
| MAML3 | -7578.0 |
| RARG | -7626.0 |
| CSNK2A2 | -7627.0 |
| ZNF704 | -7643.0 |
| PSMD12 | -7653.0 |
| ZNF839 | -7654.0 |
| NR4A3 | -7658.0 |
| UCMA | -7662.0 |
| PRKACA | -7677.0 |
| H3-3B | -7678.0 |
| PSMD11 | -7679.0 |
| TCF7L1 | -7691.0 |
| SRSF9 | -7714.0 |
| SRC | -7717.0 |
| ZNF221 | -7724.0 |
| ZNF19 | -7749.0 |
| COL1A1 | -7764.0 |
| VDR | -7781.0 |
| RBM14 | -7801.0 |
| MAML2 | -7802.0 |
| TFAP2B | -7810.0 |
| ZFHX3 | -7826.0 |
| ZNF706 | -7831.0 |
| PSMB1 | -7961.0 |
| ZNF573 | -7997.0 |
| REST | -8014.0 |
| ICE1 | -8022.0 |
| TAF6 | -8029.0 |
| ICE2 | -8038.0 |
| ZNF460 | -8042.0 |
| ZNF585A | -8062.0 |
| NFYA | -8063.0 |
| NELFCD | -8126.0 |
| MSTN | -8128.0 |
| CHEK2 | -8164.0 |
| TAF5 | -8165.0 |
| ZNF184 | -8172.0 |
| TCF7 | -8239.0 |
| RFC4 | -8250.0 |
| YEATS4 | -8274.0 |
| RPA2 | -8285.0 |
| MSX2 | -8297.0 |
| BCL6 | -8299.0 |
| YAP1 | -8303.0 |
| MED8 | -8318.0 |
| ZNF543 | -8331.0 |
| PPP1R13L | -8334.0 |
| PVALB | -8335.0 |
| ZNF287 | -8375.0 |
| NR2C1 | -8380.0 |
| RARB | -8402.0 |
| PSMB8 | -8422.0 |
| COX20 | -8444.0 |
| AURKA | -8497.0 |
| TP53RK | -8518.0 |
| ZNF440 | -8527.0 |
| CDK9 | -8530.0 |
| POLR2C | -8531.0 |
| CAMK2A | -8545.0 |
| PSMC3 | -8583.0 |
| ZNF730 | -8589.0 |
| SUMO1 | -8595.0 |
| PSMC2 | -8605.0 |
| BTG1 | -8622.0 |
| CYCS | -8627.0 |
| CSTF3 | -8639.0 |
| ZFP69B | -8640.0 |
| SLBP | -8649.0 |
| PSME2 | -8655.0 |
| ZNF415 | -8660.0 |
| GTF2H5 | -8690.0 |
| RUNX3 | -8702.0 |
| MDM4 | -8703.0 |
| CDK13 | -8705.0 |
| NUDT21 | -8713.0 |
| FOS | -8732.0 |
| POLR2L | -8763.0 |
| ZNF10 | -8785.0 |
| COX5A | -8790.0 |
| LDB1 | -8818.0 |
| SUPT16H | -8823.0 |
| SMARCD3 | -8832.0 |
| RPS27A | -8850.0 |
| CCNB1 | -8866.0 |
| NLRC4 | -8873.0 |
| FANCD2 | -8906.0 |
| CSTF1 | -8908.0 |
| ZNF566 | -8912.0 |
| SESN3 | -8921.0 |
| PRDX2 | -8955.0 |
| CDK5 | -8961.0 |
| ZNF641 | -8968.0 |
| NRBF2 | -8986.0 |
| CITED2 | -8994.0 |
| ZNF420 | -9003.0 |
| LMO2 | -9009.0 |
| POLR2E | -9019.0 |
| ZNF180 | -9030.0 |
| PSMB4 | -9031.0 |
| TEAD3 | -9041.0 |
| PSMC4 | -9044.0 |
| ZNF548 | -9072.0 |
| GTF2E1 | -9092.0 |
| ZNF692 | -9106.0 |
| ZNF483 | -9127.0 |
| COX8A | -9132.0 |
| ZNF514 | -9139.0 |
| MMP13 | -9144.0 |
| NR1I2 | -9180.0 |
| MET | -9188.0 |
| RAD1 | -9205.0 |
| ABCA6 | -9217.0 |
| ZNF34 | -9236.0 |
| SCO2 | -9255.0 |
| NFE2 | -9295.0 |
| RTF1 | -9296.0 |
| SRSF2 | -9315.0 |
| ZNF155 | -9326.0 |
| CR1 | -9360.0 |
| SNRPE | -9363.0 |
| NKX2-5 | -9376.0 |
| H2BC6 | -9394.0 |
| GLI2 | -9440.0 |
| HAND2 | -9455.0 |
| ZNF568 | -9470.0 |
| ZNF334 | -9538.0 |
| HNF4G | -9541.0 |
| JUNB | -9560.0 |
| RAD51 | -9561.0 |
| SRF | -9605.0 |
| ITGA5 | -9630.0 |
| PSMB3 | -9639.0 |
| ZNF385A | -9669.0 |
| CDK4 | -9680.0 |
| PHAX | -9704.0 |
| ZNF677 | -9714.0 |
| H2BC11 | -9747.0 |
| ZNF529 | -9750.0 |
| ZNF547 | -9751.0 |
| COX18 | -9758.0 |
| SP7 | -9799.0 |
| OCLN | -9800.0 |
| RNU11 | -9811.0 |
| NCBP1 | -9863.0 |
| ZNF274 | -9876.0 |
| POMC | -9886.0 |
| TBP | -9896.0 |
| PSMC5 | -9926.0 |
| KIT | -9936.0 |
| ZNF565 | -10006.0 |
| ELOA2 | -10016.0 |
| TRIM63 | -10094.0 |
| SRSF7 | -10103.0 |
| RAD50 | -10110.0 |
| SIRT3 | -10158.0 |
| DDB2 | -10194.0 |
| H4C6 | -10210.0 |
| NOTCH2 | -10216.0 |
| CGB8 | -10224.0 |
| ZNF727 | -10277.0 |
| ZNF77 | -10282.0 |
| ANAPC16 | -10301.0 |
| YWHAH | -10317.0 |
| MED26 | -10372.0 |
| XPO1 | -10380.0 |
| DDX39B | -10409.0 |
| MIR137 | -10415.0 |
| SKIC8 | -10418.0 |
| G6PC1 | -10450.0 |
| ZNF688 | -10460.0 |
| H3C4 | -10465.0 |
| ZNF429 | -10483.0 |
| TAF15 | -10497.0 |
| E2F1 | -10504.0 |
| ARNT2 | -10513.0 |
| H3C12 | -10530.0 |
| MAGOHB | -10533.0 |
| PSMD13 | -10647.0 |
| VENTX | -10652.0 |
| TAF10 | -10658.0 |
| H3C1 | -10687.0 |
| SRSF3 | -10721.0 |
| BTG2 | -10734.0 |
| YBX1 | -10749.0 |
| MAML1 | -10824.0 |
| FASLG | -10903.0 |
| NR1I3 | -10990.0 |
| ZNF649 | -10994.0 |
| ZNF382 | -10998.0 |
| ZNF354A | -11012.0 |
| ELL3 | -11029.0 |
| H2AC7 | -11040.5 |
| H2BC7 | -11040.5 |
| H4C1 | -11106.0 |
| L3MBTL1 | -11141.0 |
| DDIT3 | -11169.0 |
| ZNF671 | -11187.0 |
| PSMB7 | -11240.0 |
| PMAIP1 | -11280.0 |
| ZNF92 | -11290.0 |
| H2AC14 | -11332.0 |
| RGCC | -11338.0 |
| RNU12 | -11339.0 |
| SERPINB13 | -11380.0 |
| H4C8 | -11506.0 |
| ZNF320 | -11619.0 |
| ZNF101 | -11672.0 |
| ZNF658 | -11679.0 |
| H2BC14 | -11709.0 |
| AGO1 | -11740.0 |
| NDRG1 | -11833.0 |
| CDKN2B | -11853.0 |
| ZNF860 | -11899.0 |
| FOXO6 | -11930.0 |
| ZNF732 | -12008.0 |
| ZNF595 | -12062.0 |
| ZNF676 | -12250.0 |
| ZNF586 | -12272.0 |
REACTOME_METAL_SEQUESTRATION_BY_ANTIMICROBIAL_PROTEINS
| 1055 | |
|---|---|
| set | REACTOME_METAL_SEQUESTRATION_BY_ANTIMICROBIAL_PROTEINS |
| setSize | 6 |
| pANOVA | 0.000123 |
| s.dist | -0.905 |
| p.adjustANOVA | 0.0507 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| S100A8 | -12422 |
| S100A7A | -12159 |
| S100A9 | -12138 |
| LTF | -11083 |
| S100A7 | -10923 |
| LCN2 | -9600 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| S100A8 | -12422 |
| S100A7A | -12159 |
| S100A9 | -12138 |
| LTF | -11083 |
| S100A7 | -10923 |
| LCN2 | -9600 |
REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL
| 369 | |
|---|---|
| set | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL |
| setSize | 122 |
| pANOVA | 0.000206 |
| s.dist | -0.194 |
| p.adjustANOVA | 0.0678 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| KIR2DL4 | -12364 |
| TREM2 | -12299 |
| KIR2DL1 | -12286 |
| LILRB3 | -12183 |
| CD300LB | -12125 |
| TYROBP | -12086 |
| SIGLEC12 | -12074 |
| LILRB2 | -12044 |
| CD3D | -12029 |
| SLAMF7 | -11982 |
| FCGR3A | -11856 |
| KLRD1 | -11840 |
| TREML4 | -11594 |
| CD1C | -11479 |
| CD33 | -11453 |
| HCST | -11450 |
| CD300LG | -11449 |
| CD300A | -11128 |
| TREML1 | -11112 |
| LAIR2 | -11103 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| KIR2DL4 | -12364 |
| TREM2 | -12299 |
| KIR2DL1 | -12286 |
| LILRB3 | -12183 |
| CD300LB | -12125 |
| TYROBP | -12086 |
| SIGLEC12 | -12074 |
| LILRB2 | -12044 |
| CD3D | -12029 |
| SLAMF7 | -11982 |
| FCGR3A | -11856 |
| KLRD1 | -11840 |
| TREML4 | -11594 |
| CD1C | -11479 |
| CD33 | -11453 |
| HCST | -11450 |
| CD300LG | -11449 |
| CD300A | -11128 |
| TREML1 | -11112 |
| LAIR2 | -11103 |
| KIR3DL2 | -10816 |
| LILRB4 | -10801 |
| TREM1 | -10744 |
| CD3G | -10696 |
| SIGLEC9 | -10599 |
| NCR1 | -10523 |
| ICAM3 | -9983 |
| COLEC12 | -9712 |
| COL17A1 | -9643 |
| KLRG1 | -9637 |
| B2M | -9168 |
| SIGLEC6 | -9105 |
| SH2D1B | -8882 |
| CD96 | -8754 |
| ICAM5 | -8488 |
| CLEC4G | -8469 |
| CD1D | -8465 |
| VCAM1 | -8459 |
| ICAM1 | -8394 |
| CD300E | -8152 |
| COL2A1 | -8080 |
| COL1A1 | -7764 |
| PILRB | -7740 |
| SLAMF6 | -7739 |
| SFTPD | -7570 |
| LILRA4 | -7542 |
| CD22 | -6712 |
| ULBP1 | -6171 |
| OSCAR | -6111 |
| PIANP | -6071 |
| ITGA4 | -5941 |
| CXADR | -5876 |
| PILRA | -5508 |
| HLA-G | -5489 |
| HLA-E | -5359 |
| LILRA2 | -5271 |
| MICA | -5204 |
| CD3E | -5138 |
| CD8A | -4722 |
| MADCAM1 | -4605 |
| KLRK1 | -4600 |
| ITGAL | -4475 |
| JAML | -4343 |
| CD8B | -3886 |
| SIGLEC10 | -3795 |
| SIGLEC8 | -3097 |
| KLRF1 | -2925 |
| CLEC2D | -2718 |
| CD1B | -2673 |
| CDH1 | -2401 |
| KLRB1 | -2326 |
| CD300C | -2195 |
| LILRB5 | -1824 |
| LILRA3 | -1707 |
| SIGLEC7 | -1570 |
| HLA-B | -1486 |
| ICAM4 | -1292 |
| ITGB7 | -1131 |
| ITGB2 | -786 |
| CD160 | -474 |
| TREML2 | -204 |
| CD300LF | 203 |
| SIGLEC1 | 547 |
| HLA-F | 595 |
| COL1A2 | 720 |
| PVR | 1184 |
| RAET1E | 1387 |
| CD34 | 1430 |
| SELL | 1560 |
| CLEC2B | 1614 |
| HLA-A | 1643 |
| CD247 | 1766 |
| ITGB1 | 1812 |
| NCR2 | 1871 |
| HLA-C | 2005 |
| NCR3 | 2471 |
| NCR3LG1 | 2620 |
| CD81 | 2666 |
| NECTIN2 | 2771 |
| SIGLEC11 | 2787 |
| CRTAM | 3197 |
| CD226 | 3558 |
| CD40 | 3591 |
| C3 | 3889 |
| MICB | 3911 |
| CD200R1 | 4233 |
| COL3A1 | 4740 |
| KIR3DL1 | 4995 |
| LAIR1 | 5189 |
| ULBP3 | 5350 |
| CD200 | 5492 |
| KLRC1 | 6490 |
| CD19 | 6744 |
| CD300LD | 7089 |
| NPDC1 | 7192 |
| IFITM1 | 7284 |
| LILRB1 | 7326 |
| LILRA1 | 8144 |
| SIGLEC5 | 8257 |
| LILRA5 | 8819 |
| CD1A | 9162 |
| ICAM2 | 9169 |
REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL
| 397 | |
|---|---|
| set | REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL |
| setSize | 129 |
| pANOVA | 0.000253 |
| s.dist | -0.187 |
| p.adjustANOVA | 0.0694 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| PSG11 | -12204 |
| PSG4 | -12161 |
| CEACAM6 | -12099 |
| SIRPA | -11868 |
| FCAMR | -11813 |
| CD48 | -11733 |
| SELPLG | -11657 |
| CD2 | -11651 |
| SDC3 | -11524 |
| SLC7A8 | -11439 |
| MMP1 | -11252 |
| FCER1G | -11146 |
| CEACAM3 | -11077 |
| NRAS | -10906 |
| TREM1 | -10744 |
| APOB | -10737 |
| ANGPT4 | -10692 |
| SDC1 | -10571 |
| CD84 | -10319 |
| VPREB3 | -9981 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| PSG11 | -12204 |
| PSG4 | -12161 |
| CEACAM6 | -12099 |
| SIRPA | -11868 |
| FCAMR | -11813 |
| CD48 | -11733 |
| SELPLG | -11657 |
| CD2 | -11651 |
| SDC3 | -11524 |
| SLC7A8 | -11439 |
| MMP1 | -11252 |
| FCER1G | -11146 |
| CEACAM3 | -11077 |
| NRAS | -10906 |
| TREM1 | -10744 |
| APOB | -10737 |
| ANGPT4 | -10692 |
| SDC1 | -10571 |
| CD84 | -10319 |
| VPREB3 | -9981 |
| GRB2 | -9911 |
| TEK | -9854 |
| JCHAIN | -9665 |
| ITGA5 | -9630 |
| OLR1 | -9425 |
| INPP5D | -9371 |
| PSG1 | -9224 |
| CEACAM1 | -9075 |
| PF4V1 | -8925 |
| PSG7 | -8657 |
| GYPC | -8372 |
| CD244 | -8144 |
| MIF | -7988 |
| CEACAM8 | -7864 |
| COL1A1 | -7764 |
| SRC | -7717 |
| CD177 | -7620 |
| DOK2 | -7250 |
| CEACAM5 | -7039 |
| TNFRSF10B | -6896 |
| SLC7A11 | -6859 |
| CD74 | -6783 |
| PSG5 | -6703 |
| PIK3CA | -6283 |
| PTPN6 | -6254 |
| ATP1B1 | -6242 |
| F11R | -6188 |
| PIK3R2 | -6034 |
| ITGA4 | -5941 |
| CXADR | -5876 |
| GRB7 | -5849 |
| PIK3R1 | -5692 |
| SLC7A10 | -5467 |
| CAV1 | -5299 |
| ANGPT1 | -5147 |
| MAG | -5021 |
| PSG2 | -4937 |
| JAM2 | -4933 |
| SELE | -4812 |
| SPN | -4701 |
| ITGB3 | -4662 |
| ITGAL | -4475 |
| JAML | -4343 |
| F2 | -4275 |
| MERTK | -3963 |
| GRB14 | -3725 |
| FN1 | -3659 |
| ATP1B3 | -3491 |
| SLC16A8 | -3021 |
| SLC3A2 | -3000 |
| SLC7A6 | -2807 |
| SDC2 | -2611 |
| LCK | -2552 |
| TNFRSF10A | -2483 |
| VPREB1 | -2431 |
| GYPA | -2386 |
| ITGA3 | -2152 |
| ATP1B2 | -1877 |
| SHC1 | -1802 |
| GPC1 | -1766 |
| IGLL1 | -1501 |
| SLC7A7 | -1468 |
| FYN | -1185 |
| PLCG1 | -1095 |
| ITGB2 | -786 |
| BSG | -741 |
| ITGA6 | -421 |
| CD47 | -413 |
| GP6 | -218 |
| TNFRSF10D | -22 |
| KRAS | 94 |
| HRAS | 462 |
| TGFB1 | 605 |
| COL1A2 | 720 |
| ESAM | 797 |
| SLC16A3 | 819 |
| ANGPT2 | 829 |
| PECAM1 | 1067 |
| THBD | 1180 |
| SELL | 1560 |
| ITGAX | 1566 |
| PPIA | 1750 |
| ITGB1 | 1812 |
| CD44 | 1832 |
| SLC16A1 | 2054 |
| PTPN11 | 2193 |
| ITGAM | 2304 |
| PROS1 | 2314 |
| PIK3CB | 2393 |
| LYN | 2809 |
| YES1 | 2889 |
| PF4 | 2971 |
| ITGAV | 3093 |
| PICK1 | 3386 |
| EPCAM | 3434 |
| SLC7A9 | 3666 |
| CD58 | 4480 |
| SELP | 4504 |
| SOS1 | 4627 |
| GLG1 | 4838 |
| SIRPG | 4972 |
| PPIL2 | 6791 |
| JAM3 | 6847 |
| PROC | 7012 |
| SLC7A5 | 7147 |
| PROCR | 7541 |
| SDC4 | 7581 |
| PSG9 | 8339 |
| PSG8 | 8988 |
REACTOME_FERTILIZATION
| 53 | |
|---|---|
| set | REACTOME_FERTILIZATION |
| setSize | 26 |
| pANOVA | 0.000445 |
| s.dist | -0.398 |
| p.adjustANOVA | 0.104 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| ACR | -12264 |
| IZUMO1 | -12080 |
| CATSPER4 | -11903 |
| CATSPER3 | -11770 |
| B4GALT1 | -11324 |
| ZP1 | -11255 |
| OVGP1 | -10916 |
| ADAM20 | -10677 |
| HVCN1 | -10189 |
| CATSPER1 | -10173 |
| CD9 | -10160 |
| ZP4 | -9385 |
| IZUMO2 | -8749 |
| ADAM30 | -8666 |
| IZUMO3 | -7395 |
| CATSPERD | -7147 |
| ZP3 | -3346 |
| KCNU1 | -3114 |
| SPAM1 | -2102 |
| CATSPERG | 168 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ACR | -12264 |
| IZUMO1 | -12080 |
| CATSPER4 | -11903 |
| CATSPER3 | -11770 |
| B4GALT1 | -11324 |
| ZP1 | -11255 |
| OVGP1 | -10916 |
| ADAM20 | -10677 |
| HVCN1 | -10189 |
| CATSPER1 | -10173 |
| CD9 | -10160 |
| ZP4 | -9385 |
| IZUMO2 | -8749 |
| ADAM30 | -8666 |
| IZUMO3 | -7395 |
| CATSPERD | -7147 |
| ZP3 | -3346 |
| KCNU1 | -3114 |
| SPAM1 | -2102 |
| CATSPERG | 168 |
| ADAM21 | 516 |
| CATSPERB | 862 |
| ZP2 | 1479 |
| IZUMO4 | 1825 |
| ADAM2 | 8038 |
| CATSPER2 | 8785 |
REACTOME_DEVELOPMENTAL_BIOLOGY
| 76 | |
|---|---|
| set | REACTOME_DEVELOPMENTAL_BIOLOGY |
| setSize | 1115 |
| pANOVA | 0.000587 |
| s.dist | -0.061 |
| p.adjustANOVA | 0.121 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| KRTAP19-5 | -12384 |
| SPRR2E | -12351 |
| KRT16 | -12324 |
| TREM2 | -12299 |
| SPRR1B | -12173 |
| KRTAP5-6 | -12156 |
| HOXA2 | -12116 |
| KRT83 | -12115 |
| TYROBP | -12086 |
| KRTAP9-9 | -12083 |
| KRTAP5-9 | -11994 |
| KRT2 | -11966 |
| LCE1A | -11944 |
| KRTAP9-6 | -11852 |
| KRTAP4-11 | -11817 |
| WNT10B | -11797 |
| SCN11A | -11792 |
| KRTAP8-1 | -11785 |
| KRTAP4-6 | -11769 |
| IAPP | -11766 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| KRTAP19-5 | -12384.0 |
| SPRR2E | -12351.0 |
| KRT16 | -12324.0 |
| TREM2 | -12299.0 |
| SPRR1B | -12173.0 |
| KRTAP5-6 | -12156.0 |
| HOXA2 | -12116.0 |
| KRT83 | -12115.0 |
| TYROBP | -12086.0 |
| KRTAP9-9 | -12083.0 |
| KRTAP5-9 | -11994.0 |
| KRT2 | -11966.0 |
| LCE1A | -11944.0 |
| KRTAP9-6 | -11852.0 |
| KRTAP4-11 | -11817.0 |
| WNT10B | -11797.0 |
| SCN11A | -11792.0 |
| KRTAP8-1 | -11785.0 |
| KRTAP4-6 | -11769.0 |
| IAPP | -11766.0 |
| KRT78 | -11755.0 |
| RPL35A | -11731.0 |
| H2BC14 | -11709.0 |
| KRTAP15-1 | -11665.0 |
| KRTAP9-1 | -11626.0 |
| KRT33B | -11608.0 |
| KRTAP1-3 | -11593.0 |
| KRTAP25-1 | -11576.0 |
| KRT15 | -11575.0 |
| KRTAP21-1 | -11550.0 |
| SPRR2G | -11548.0 |
| KRT31 | -11521.0 |
| H4C8 | -11506.0 |
| KRTAP12-4 | -11500.0 |
| KRTAP16-1 | -11495.0 |
| LGI1 | -11474.0 |
| KRTAP1-4 | -11436.0 |
| DPPA4 | -11434.0 |
| PKP2 | -11410.0 |
| KRTAP5-1 | -11409.0 |
| WNT3A | -11393.0 |
| PI3 | -11389.0 |
| KRTAP9-3 | -11357.0 |
| KRTAP9-4 | -11351.0 |
| H2AC14 | -11332.0 |
| SEMA4A | -11328.0 |
| RPL12 | -11317.0 |
| KRTAP12-1 | -11307.0 |
| ADAM11 | -11292.0 |
| RRAS | -11267.0 |
| LPL | -11262.0 |
| KRT3 | -11248.0 |
| GFRA3 | -11247.0 |
| PSMB7 | -11240.0 |
| RHOB | -11238.0 |
| SCN2B | -11183.0 |
| CSF3R | -11162.0 |
| H4C1 | -11106.0 |
| DSCAML1 | -11093.0 |
| MMP9 | -11092.0 |
| MED28 | -11087.0 |
| MEF2D | -11073.0 |
| KRT80 | -11063.0 |
| H2AC7 | -11040.5 |
| H2BC7 | -11040.5 |
| SCN4B | -11024.0 |
| LCE4A | -10962.0 |
| RPL10A | -10960.0 |
| MAPK12 | -10918.0 |
| NRAS | -10906.0 |
| WT1 | -10900.0 |
| MAML1 | -10824.0 |
| ST14 | -10739.0 |
| MED11 | -10715.0 |
| KRT33A | -10703.0 |
| COL5A1 | -10699.0 |
| H3C1 | -10687.0 |
| LIPN | -10686.0 |
| RPL23A | -10666.0 |
| PSMD13 | -10647.0 |
| RPS13 | -10627.0 |
| MAGOHB | -10533.0 |
| H3C12 | -10530.0 |
| E2F1 | -10504.0 |
| H3C4 | -10465.0 |
| SHTN1 | -10463.0 |
| KRTAP26-1 | -10449.0 |
| RPL18 | -10404.0 |
| KRTAP19-3 | -10389.0 |
| MED26 | -10372.0 |
| CACNA1C | -10343.0 |
| DAND5 | -10331.0 |
| PLXNB1 | -10321.0 |
| KRTAP2-4 | -10296.0 |
| KRT72 | -10287.0 |
| LGI3 | -10285.0 |
| RPL35 | -10232.0 |
| NANOG | -10213.0 |
| H4C6 | -10210.0 |
| SCN8A | -10207.0 |
| LIPM | -10203.0 |
| AP2S1 | -10172.0 |
| KLK12 | -10161.0 |
| NTN3 | -10146.0 |
| KRT13 | -10140.0 |
| ARPC4 | -10108.0 |
| KRTAP10-5 | -10107.0 |
| HOXA1 | -10079.0 |
| TNF | -10059.0 |
| KRT39 | -10021.0 |
| ACTB | -10011.0 |
| KLK8 | -9998.0 |
| MYL12A | -9990.0 |
| GFI1 | -9987.0 |
| MAPK13 | -9948.0 |
| PLXNA2 | -9934.0 |
| PSMC5 | -9926.0 |
| NTN1 | -9920.0 |
| ACTG1 | -9912.0 |
| GRB2 | -9911.0 |
| KRTAP5-11 | -9909.0 |
| KRTAP19-4 | -9895.0 |
| MPZ | -9881.0 |
| PTPRC | -9874.0 |
| NCBP1 | -9863.0 |
| HOXC4 | -9861.0 |
| PPP3CB | -9853.0 |
| OCLN | -9800.0 |
| KRTAP5-4 | -9752.0 |
| H2BC11 | -9747.0 |
| TUBA4A | -9708.0 |
| CASP14 | -9683.0 |
| CDK4 | -9680.0 |
| CACNG4 | -9648.0 |
| PSMB3 | -9639.0 |
| ITGA5 | -9630.0 |
| LCE3B | -9609.0 |
| RPL8 | -9570.0 |
| RPL30 | -9564.0 |
| HNF4G | -9541.0 |
| ARHGEF11 | -9516.0 |
| LHX9 | -9411.0 |
| H2BC6 | -9394.0 |
| ITGA9 | -9379.0 |
| RPS8 | -9372.0 |
| CRMP1 | -9358.0 |
| LYPLA2 | -9342.0 |
| CLTCL1 | -9266.0 |
| UNC5B | -9254.0 |
| SPTBN2 | -9204.0 |
| COL4A3 | -9201.0 |
| MET | -9188.0 |
| RPS23 | -9186.0 |
| KRTAP24-1 | -9146.0 |
| LEFTY2 | -9094.0 |
| PSMC4 | -9044.0 |
| RPL3 | -9036.0 |
| PSMB4 | -9031.0 |
| POLR2E | -9019.0 |
| RPL37 | -9016.0 |
| CDK5 | -8961.0 |
| TUBAL3 | -8959.0 |
| LCE3A | -8913.0 |
| RPLP2 | -8901.0 |
| KRT23 | -8888.0 |
| KRTAP20-1 | -8879.0 |
| RPS27A | -8850.0 |
| CAP2 | -8848.0 |
| SMARCD3 | -8832.0 |
| LDB1 | -8818.0 |
| PMP22 | -8815.0 |
| ARPC2 | -8781.0 |
| MEF2B | -8766.0 |
| POLR2L | -8763.0 |
| TGM1 | -8761.0 |
| CD36 | -8750.0 |
| NFASC | -8740.0 |
| GAB2 | -8677.0 |
| CDH15 | -8658.0 |
| PSME2 | -8655.0 |
| ADGRV1 | -8612.0 |
| PSMC2 | -8605.0 |
| PSMC3 | -8583.0 |
| TUBB4B | -8578.0 |
| PDX1 | -8577.0 |
| KRT7 | -8557.0 |
| POLR2C | -8531.0 |
| TGM5 | -8528.0 |
| FLRT3 | -8491.0 |
| KRTAP21-2 | -8479.0 |
| TBPL2 | -8478.0 |
| PAGR1 | -8471.0 |
| TIAM1 | -8442.0 |
| PSMB8 | -8422.0 |
| RARB | -8402.0 |
| SPINK5 | -8392.0 |
| RDX | -8338.0 |
| RPL36 | -8324.0 |
| MED8 | -8318.0 |
| YAP1 | -8303.0 |
| PRDM14 | -8283.0 |
| SEMA7A | -8270.0 |
| ADIPOQ | -8247.0 |
| TUBB2A | -8245.0 |
| BOC | -8244.0 |
| MYF5 | -8241.0 |
| TCF7 | -8239.0 |
| HOXD4 | -8220.0 |
| HOXD3 | -8216.0 |
| EOMES | -8175.0 |
| EBF1 | -8131.0 |
| RPS10 | -8127.0 |
| MESP2 | -8108.0 |
| COL2A1 | -8080.0 |
| KRTAP11-1 | -8071.0 |
| SRGAP3 | -8052.0 |
| SLIT1 | -8025.0 |
| KALRN | -7964.0 |
| PSMB1 | -7961.0 |
| LAMB1 | -7960.0 |
| ABLIM3 | -7947.0 |
| SPINK9 | -7943.0 |
| RPS15A | -7940.0 |
| FGFR1 | -7913.0 |
| SPRR2F | -7904.0 |
| RPS18 | -7899.0 |
| LGI2 | -7895.0 |
| PRKAR2A | -7893.0 |
| ACVR1B | -7881.0 |
| RPS6 | -7875.0 |
| EFNA1 | -7822.0 |
| MAML2 | -7802.0 |
| CDC42 | -7738.0 |
| SLIT3 | -7727.0 |
| FOXF1 | -7719.0 |
| SRC | -7717.0 |
| SCN2A | -7700.0 |
| PSMD11 | -7679.0 |
| H3-3B | -7678.0 |
| PRKACA | -7677.0 |
| PSMD12 | -7653.0 |
| FARP2 | -7636.0 |
| CSNK2A2 | -7627.0 |
| RARG | -7626.0 |
| RAP1GAP | -7617.0 |
| KRT36 | -7602.0 |
| CACNB4 | -7597.0 |
| MAML3 | -7578.0 |
| CACNA1D | -7568.0 |
| NRP2 | -7518.0 |
| UBC | -7516.0 |
| STX1B | -7507.0 |
| RPL27A | -7502.0 |
| KRTAP1-5 | -7501.0 |
| SPI1 | -7492.0 |
| MIXL1 | -7465.0 |
| CELA2A | -7449.0 |
| KRTAP20-2 | -7447.0 |
| CNTN6 | -7444.0 |
| H2AZ2 | -7419.0 |
| GATA4 | -7404.0 |
| MSGN1 | -7359.0 |
| GAP43 | -7356.0 |
| MED15 | -7351.0 |
| RPL7 | -7346.0 |
| COL9A3 | -7344.0 |
| MAGOH | -7338.0 |
| DPYSL3 | -7317.0 |
| LHX2 | -7312.0 |
| PTK2 | -7305.0 |
| DOK2 | -7250.0 |
| PSMA1 | -7186.0 |
| EFNB3 | -7184.0 |
| KRT34 | -7167.0 |
| RPS25 | -7128.0 |
| LCE2C | -7121.0 |
| RPL41 | -7109.0 |
| KRT9 | -7098.0 |
| POLR2I | -7081.0 |
| SREBF2 | -7045.0 |
| SIAH2 | -7035.0 |
| CSNK2A1 | -7031.0 |
| KRTAP2-2 | -7022.0 |
| H2BC1 | -7004.0 |
| NODAL | -6994.0 |
| PLIN1 | -6990.0 |
| SPRR2D | -6989.0 |
| MED13L | -6979.0 |
| PAX6 | -6976.0 |
| KRTAP21-3 | -6938.0 |
| RPL15 | -6931.0 |
| VAV2 | -6903.0 |
| FOXD3 | -6868.0 |
| KRT17 | -6818.0 |
| MAPK11 | -6815.0 |
| ST8SIA2 | -6777.0 |
| RHOC | -6770.0 |
| KRTAP13-3 | -6736.0 |
| SCN5A | -6727.0 |
| SEMA3E | -6723.0 |
| H2BC5 | -6716.0 |
| CNTNAP1 | -6713.0 |
| WNT1 | -6699.0 |
| RET | -6690.0 |
| CEBPE | -6672.0 |
| RPS2 | -6644.0 |
| TEAD1 | -6640.0 |
| RPS14 | -6614.0 |
| DLL3 | -6577.0 |
| UBB | -6558.0 |
| IL6R | -6551.0 |
| NCAN | -6547.0 |
| SPTB | -6517.0 |
| SCN3A | -6493.0 |
| RBX1 | -6489.0 |
| PSMD4 | -6474.0 |
| KRTAP9-2 | -6473.0 |
| NR6A1 | -6469.0 |
| NAB2 | -6468.0 |
| ITSN1 | -6429.0 |
| KRTAP5-5 | -6407.0 |
| RPL17 | -6404.0 |
| KRT40 | -6390.0 |
| RPS27 | -6385.0 |
| SPTA1 | -6367.0 |
| SALL4 | -6365.0 |
| CFL1 | -6343.0 |
| GAB1 | -6306.0 |
| LEP | -6303.0 |
| KRTAP6-3 | -6295.0 |
| PIK3CA | -6283.0 |
| ST8SIA4 | -6280.0 |
| KRT28 | -6269.0 |
| CLDN7 | -6230.0 |
| RPL38 | -6209.0 |
| RBM8A | -6194.0 |
| RPS7 | -6174.0 |
| KRTAP13-1 | -6157.0 |
| KRTAP29-1 | -6152.0 |
| PRKACB | -6133.0 |
| DSG1 | -6110.0 |
| PSMB5 | -6101.0 |
| ALCAM | -6062.0 |
| KRTAP2-1 | -6051.0 |
| PBX1 | -6046.0 |
| PIK3R2 | -6034.0 |
| LCE6A | -6022.0 |
| SCN10A | -6013.0 |
| DLG4 | -5964.0 |
| PSMB9 | -5962.0 |
| RPL28 | -5935.0 |
| HNF4A | -5931.0 |
| MED6 | -5892.0 |
| GRB7 | -5849.0 |
| LCE3E | -5838.0 |
| RPLP0 | -5821.0 |
| H2BC3 | -5808.0 |
| KRTAP10-7 | -5807.0 |
| PSMA7 | -5784.0 |
| RPS24 | -5735.0 |
| NFKB1 | -5696.0 |
| PIK3R1 | -5692.0 |
| PAK6 | -5653.0 |
| RAC1 | -5651.0 |
| AJUBA | -5639.0 |
| MED20 | -5623.0 |
| H2BC26 | -5603.0 |
| RANBP9 | -5587.0 |
| DNM2 | -5584.0 |
| PSMD3 | -5582.0 |
| KLK5 | -5568.0 |
| PAK5 | -5551.0 |
| MYC | -5550.0 |
| SHC3 | -5542.0 |
| CXCR4 | -5539.0 |
| GRIN1 | -5535.0 |
| PSEN1 | -5526.0 |
| GRIN2B | -5523.0 |
| H4C5 | -5492.0 |
| CHD9 | -5476.0 |
| EZH2 | -5457.0 |
| MYL9 | -5455.0 |
| RPTN | -5434.0 |
| ZSCAN10 | -5428.0 |
| PFN1 | -5408.0 |
| COL5A2 | -5407.0 |
| TBX6 | -5378.0 |
| UNC5A | -5374.0 |
| KMT2A | -5341.0 |
| AGRN | -5326.0 |
| RPL13 | -5315.0 |
| KRTAP10-2 | -5305.0 |
| NKX2-2 | -5293.0 |
| PSMA4 | -5279.0 |
| H2BC4 | -5269.0 |
| KRTAP5-3 | -5229.0 |
| LAMA2 | -5227.0 |
| MYF6 | -5194.0 |
| LIN28A | -5169.0 |
| DPYSL2 | -5142.0 |
| PSMB11 | -5123.0 |
| KRT14 | -5114.0 |
| RPL21 | -5078.0 |
| CSTA | -5056.0 |
| GCK | -5044.0 |
| KRT6C | -5039.0 |
| PSMA2 | -5037.0 |
| MAG | -5021.0 |
| NCBP2 | -4990.0 |
| RELN | -4972.0 |
| DPYSL5 | -4948.0 |
| RPS3 | -4929.0 |
| CLTA | -4928.0 |
| HOXA3 | -4863.0 |
| ERBB2 | -4838.0 |
| GSK3B | -4830.0 |
| KRT6A | -4753.0 |
| DPYSL4 | -4723.0 |
| EZR | -4698.0 |
| ONECUT1 | -4693.0 |
| CDKN1A | -4689.0 |
| ITGB3 | -4662.0 |
| PPARG | -4640.0 |
| TUBA1B | -4626.0 |
| KRTAP22-1 | -4622.0 |
| CNTN1 | -4616.0 |
| MYB | -4604.0 |
| MAP2K1 | -4569.0 |
| RPL11 | -4567.0 |
| SEMA5A | -4559.0 |
| HNF1A | -4519.0 |
| ADAM23 | -4516.0 |
| H2AC20 | -4507.0 |
| RBBP5 | -4481.0 |
| RPS26 | -4458.0 |
| TRPC7 | -4442.0 |
| FGF2 | -4432.0 |
| ANK1 | -4426.0 |
| ACVR2B | -4415.0 |
| MYH14 | -4399.0 |
| PSMB10 | -4396.0 |
| GSPT1 | -4335.0 |
| CSNK2B | -4328.0 |
| MYOG | -4317.0 |
| RPL9 | -4316.0 |
| PSME4 | -4311.0 |
| RPLP1 | -4306.0 |
| TBXT | -4304.0 |
| H2BC17 | -4265.0 |
| CDX2 | -4263.0 |
| TCHH | -4238.0 |
| PSMA6 | -4225.0 |
| ADAM10 | -4196.0 |
| TRPC3 | -4188.0 |
| HES1 | -4159.0 |
| KRTAP10-4 | -4139.0 |
| CDH4 | -4132.0 |
| H2AJ | -4124.0 |
| EPHB2 | -4089.0 |
| DSG4 | -4088.0 |
| CACNA1I | -4081.0 |
| COL5A3 | -4080.0 |
| TUBA4B | -4076.0 |
| MYO10 | -4070.0 |
| TRIO | -4048.0 |
| FAU | -4024.0 |
| NR5A2 | -3946.0 |
| RPS11 | -3891.0 |
| SCN3B | -3845.0 |
| EPAS1 | -3815.0 |
| NOG | -3798.0 |
| LIMK1 | -3755.0 |
| NRCAM | -3733.0 |
| COL4A2 | -3720.0 |
| RBBP4 | -3719.0 |
| RPL39L | -3705.0 |
| MAPK14 | -3702.0 |
| KRTAP4-7 | -3641.0 |
| ANK2 | -3638.0 |
| KRTAP10-11 | -3635.0 |
| FLI1 | -3575.0 |
| PIAS2 | -3569.0 |
| RPL18A | -3568.0 |
| ABL1 | -3561.0 |
| KRTAP19-7 | -3545.0 |
| PLXNA4 | -3466.0 |
| KRTAP12-3 | -3431.0 |
| PSENEN | -3417.0 |
| CD72 | -3415.0 |
| PRKCA | -3400.0 |
| POU3F1 | -3373.0 |
| MED19 | -3361.0 |
| H2AZ1 | -3348.0 |
| ENAH | -3289.0 |
| CDK2 | -3257.0 |
| DSCAM | -3256.0 |
| PERP | -3220.0 |
| SOX10 | -3201.0 |
| MYH9 | -3191.0 |
| GDF1 | -3189.0 |
| RPL31 | -3185.0 |
| TLN1 | -3177.0 |
| SEMA3A | -3147.0 |
| KRTAP19-1 | -3115.0 |
| RPL36AL | -3061.5 |
| COL6A5 | -3050.0 |
| WASL | -3046.0 |
| PSMD8 | -3004.0 |
| RPL6 | -3002.0 |
| POLR2K | -2963.0 |
| FOXA3 | -2920.0 |
| HNF1B | -2909.0 |
| MBP | -2900.0 |
| EPHA2 | -2865.0 |
| MED29 | -2846.0 |
| NEUROG3 | -2841.0 |
| PRKCQ | -2828.0 |
| ROBO1 | -2800.0 |
| CTNNA2 | -2748.0 |
| MYOD1 | -2746.0 |
| CDK5R1 | -2738.0 |
| NOTO | -2735.0 |
| KRTAP27-1 | -2722.0 |
| PSMD9 | -2679.0 |
| KRT85 | -2669.0 |
| ELOB | -2654.0 |
| SPRR3 | -2641.0 |
| PIK3R3 | -2629.0 |
| KAT2A | -2622.0 |
| SRGAP1 | -2619.0 |
| STX1A | -2616.0 |
| SDC2 | -2611.0 |
| PSEN2 | -2603.0 |
| DOK1 | -2596.0 |
| DOCK1 | -2571.0 |
| MAFB | -2564.0 |
| CXCL12 | -2561.0 |
| FOXL2 | -2547.0 |
| LCE1C | -2506.0 |
| H4C9 | -2491.0 |
| H4C2 | -2471.0 |
| NCSTN | -2455.0 |
| H3C6 | -2432.0 |
| LAMC1 | -2430.0 |
| PCSK6 | -2404.0 |
| CDH1 | -2401.0 |
| TGS1 | -2388.0 |
| VLDLR | -2384.0 |
| SLC2A4 | -2372.0 |
| ETF1 | -2365.0 |
| MED4 | -2347.0 |
| PCK1 | -2327.0 |
| PKP1 | -2282.0 |
| THRAP3 | -2246.0 |
| H2BC21 | -2245.0 |
| ARTN | -2241.0 |
| STAT3 | -2231.0 |
| LIPJ | -2225.0 |
| PSMD1 | -2198.0 |
| MED25 | -2048.0 |
| RPL5 | -2041.0 |
| MEF2A | -2036.0 |
| ADGRG6 | -2030.0 |
| RPL29 | -2004.0 |
| HJV | -1992.0 |
| ROCK2 | -1985.0 |
| NELL2 | -1967.0 |
| AMH | -1961.0 |
| HIF3A | -1960.0 |
| SOX2 | -1935.0 |
| ACTR3 | -1924.0 |
| TCF4 | -1896.0 |
| UPF2 | -1846.0 |
| KRT8 | -1842.0 |
| PKP4 | -1817.0 |
| SHC1 | -1802.0 |
| H2AC8 | -1791.0 |
| KRT12 | -1778.0 |
| CACNB3 | -1775.0 |
| GPC1 | -1766.0 |
| RPL13A | -1763.5 |
| RXRA | -1749.0 |
| CACNB2 | -1742.0 |
| WWTR1 | -1718.0 |
| MAPK1 | -1683.0 |
| PLXNC1 | -1630.0 |
| FES | -1620.0 |
| EPHA8 | -1572.0 |
| CDK19 | -1527.0 |
| CDON | -1500.0 |
| CACNA1G | -1482.0 |
| SIAH1 | -1475.0 |
| FOXP1 | -1474.0 |
| ZNF467 | -1471.0 |
| RPL14 | -1458.0 |
| H3-3A | -1455.0 |
| UNC5C | -1444.0 |
| KIF4B | -1413.0 |
| PIK3CD | -1404.0 |
| ROBO3 | -1355.0 |
| COL4A1 | -1338.0 |
| SCN1A | -1337.0 |
| ARPC1A | -1335.0 |
| LCE2D | -1326.0 |
| KRTAP4-1 | -1317.0 |
| H3C2 | -1304.0 |
| ROBO2 | -1298.0 |
| PAX4 | -1290.0 |
| CCND3 | -1286.0 |
| RPS29 | -1284.0 |
| H2AC6 | -1218.0 |
| ZNF335 | -1198.0 |
| MAP2K2 | -1193.0 |
| FYN | -1185.0 |
| UTRN | -1155.0 |
| SCD5 | -1152.0 |
| TUBB3 | -1149.0 |
| RPS6KA1 | -1101.0 |
| HSP90AA1 | -1097.0 |
| PLCG1 | -1095.0 |
| PKNOX1 | -1090.0 |
| EVL | -1083.0 |
| DCC | -1048.0 |
| RPL37A | -1041.0 |
| ANGPTL4 | -1031.0 |
| PML | -996.0 |
| PSMD14 | -968.0 |
| POU3F2 | -944.0 |
| DMRT1 | -941.0 |
| TEAD2 | -936.0 |
| RPL22L1 | -925.0 |
| DNM1 | -921.0 |
| MAFA | -908.0 |
| LHX4 | -892.0 |
| EFNA4 | -851.0 |
| RPL7A | -848.0 |
| H3C11 | -834.0 |
| MED31 | -830.0 |
| RPS28 | -820.0 |
| LEF1 | -784.0 |
| MED1 | -765.0 |
| KAZN | -762.0 |
| MED9 | -757.0 |
| TUBA8 | -738.0 |
| DHH | -723.0 |
| NCK2 | -689.0 |
| PPL | -669.0 |
| EPHA6 | -655.0 |
| TUBA1C | -627.0 |
| LCE2A | -619.0 |
| POU5F1 | -614.0 |
| MED24 | -599.0 |
| HSP90AB1 | -579.0 |
| RPS19 | -560.0 |
| KRT38 | -556.0 |
| DOK5 | -546.0 |
| SNW1 | -525.0 |
| TEAD4 | -495.0 |
| CYP51A1 | -486.0 |
| TUBA1A | -478.0 |
| ACTR2 | -466.0 |
| GDNF | -431.0 |
| AGAP2 | -396.0 |
| KRTAP5-8 | -381.0 |
| MYH10 | -356.0 |
| RPL19 | -351.0 |
| H2BC13 | -344.0 |
| MAP2K6 | -317.0 |
| KRTAP13-4 | -307.0 |
| KRTAP6-2 | -295.0 |
| CEBPA | -272.0 |
| MED21 | -271.0 |
| FOXH1 | -270.0 |
| MSI1 | -248.0 |
| PABPC1 | -207.0 |
| H3C8 | -157.0 |
| RPS5 | -141.0 |
| GATA6 | -109.0 |
| ADIRF | -41.0 |
| RUNX1 | -31.0 |
| TUBB6 | 10.0 |
| ITGA2 | 11.0 |
| KRT86 | 32.0 |
| APH1B | 45.0 |
| PSMD5 | 47.0 |
| MED22 | 53.0 |
| CLTC | 93.0 |
| KRAS | 94.0 |
| ONECUT3 | 102.0 |
| COL6A3 | 112.0 |
| SPRR2A | 115.0 |
| ARHGAP35 | 124.0 |
| RBPJ | 129.0 |
| RFX6 | 135.0 |
| VASP | 155.0 |
| MYL6 | 238.0 |
| KRT76 | 277.0 |
| ITGA1 | 280.0 |
| SCN1B | 311.0 |
| POLR2D | 313.0 |
| TRPC1 | 354.0 |
| SHH | 385.0 |
| MEIS1 | 422.0 |
| RPS21 | 432.0 |
| NCOA6 | 434.0 |
| HRAS | 462.0 |
| JUP | 465.0 |
| RPS27L | 478.0 |
| RPS16 | 492.0 |
| ADAM22 | 493.0 |
| RARA | 519.0 |
| PPARA | 540.0 |
| PTGDS | 569.0 |
| CLASP1 | 573.0 |
| KRT81 | 588.0 |
| TGFB1 | 605.0 |
| CTCF | 624.0 |
| KRT26 | 671.0 |
| EED | 676.0 |
| MAPK8 | 717.0 |
| ARHGAP39 | 719.0 |
| POLR2F | 722.0 |
| EGFR | 756.0 |
| POLR2H | 760.0 |
| PSMA3 | 761.0 |
| NEUROD1 | 787.0 |
| GIT1 | 794.0 |
| EPHA4 | 795.0 |
| RPL32 | 844.0 |
| EFNA5 | 850.0 |
| LAMA1 | 860.0 |
| TUBB4A | 911.0 |
| NRP1 | 922.0 |
| ARHGEF28 | 934.0 |
| CDH2 | 942.0 |
| ACVR1C | 950.0 |
| ROCK1 | 965.0 |
| UPF3A | 966.0 |
| UNC5D | 976.0 |
| INSM1 | 1013.0 |
| LIMK2 | 1020.0 |
| RPL26L1 | 1044.0 |
| ITGA2B | 1047.0 |
| H2BC10 | 1052.0 |
| TRPC4 | 1054.0 |
| ARHGEF7 | 1055.0 |
| MAPK7 | 1074.0 |
| MAPK3 | 1159.0 |
| EGR2 | 1164.0 |
| RPS6KA2 | 1176.0 |
| SPINK6 | 1212.0 |
| PSMD6 | 1244.0 |
| PAK2 | 1282.0 |
| MED17 | 1290.0 |
| H2AC18 | 1298.5 |
| H2AC19 | 1298.5 |
| TRIM33 | 1307.0 |
| DSG2 | 1309.0 |
| KRT25 | 1315.0 |
| SDCBP | 1329.0 |
| RPS6KA4 | 1345.0 |
| NCOA2 | 1391.0 |
| KCNQ3 | 1412.0 |
| CNOT9 | 1414.0 |
| PRSS8 | 1488.0 |
| GSC | 1497.0 |
| ARPC1B | 1507.0 |
| EFNB2 | 1532.0 |
| RPS12 | 1537.0 |
| NCK1 | 1544.0 |
| HOXD1 | 1575.0 |
| SEMA6D | 1576.0 |
| KRTAP5-7 | 1606.0 |
| PSME3 | 1619.0 |
| POLR2G | 1673.0 |
| HSPA8 | 1683.0 |
| RASA1 | 1724.0 |
| IHH | 1726.0 |
| H2BC8 | 1727.0 |
| RGMB | 1743.0 |
| INS | 1760.0 |
| CHL1 | 1768.0 |
| SEMA6A | 1769.0 |
| IVL | 1771.0 |
| GFRA2 | 1772.0 |
| CBFB | 1784.0 |
| COL9A1 | 1799.0 |
| ITGB1 | 1812.0 |
| KLF5 | 1844.0 |
| ARHGEF12 | 1846.0 |
| KRTAP3-2 | 1850.0 |
| CREBBP | 1880.0 |
| SPTAN1 | 1882.0 |
| CACNG3 | 1898.0 |
| CACNG8 | 1920.0 |
| ABLIM1 | 1929.0 |
| KRTAP10-9 | 1930.0 |
| KRT24 | 1936.0 |
| RPSA | 1951.0 |
| SEM1 | 1961.0 |
| CNTN2 | 1987.0 |
| H4C12 | 1999.0 |
| DNM3 | 2004.0 |
| VAV3 | 2014.0 |
| COL4A4 | 2015.0 |
| LCE1F | 2039.0 |
| NEO1 | 2040.0 |
| PSMB2 | 2057.0 |
| NCOR1 | 2075.0 |
| EPHA10 | 2098.0 |
| TUBA3D | 2121.0 |
| EPHB1 | 2125.0 |
| NTN4 | 2175.0 |
| AKT3 | 2190.0 |
| PTPN11 | 2193.0 |
| SCN9A | 2241.0 |
| KRTAP5-10 | 2257.0 |
| APH1A | 2359.0 |
| DSC3 | 2372.0 |
| PIK3CB | 2393.0 |
| KRT20 | 2408.0 |
| BMP4 | 2425.0 |
| EFNA3 | 2426.0 |
| KRT82 | 2449.0 |
| RPS9 | 2453.0 |
| KRT32 | 2467.0 |
| MYO9B | 2511.0 |
| CTNNB1 | 2534.0 |
| PSMA5 | 2542.0 |
| SCN7A | 2545.0 |
| SMARCA4 | 2567.0 |
| PDLIM7 | 2572.0 |
| KRT5 | 2604.0 |
| DLL1 | 2610.0 |
| MYL12B | 2612.0 |
| POLR2B | 2622.0 |
| PSME1 | 2636.0 |
| LCE1B | 2645.0 |
| DAB1 | 2652.0 |
| ABL2 | 2659.0 |
| PSMB6 | 2700.0 |
| FOXO1 | 2723.0 |
| LHX3 | 2744.0 |
| ISL1 | 2773.0 |
| KRTAP4-3 | 2779.0 |
| AP2B1 | 2792.0 |
| LYN | 2809.0 |
| RND1 | 2848.0 |
| PAXIP1 | 2855.0 |
| SLIT2 | 2865.0 |
| YES1 | 2889.0 |
| KLK14 | 2895.0 |
| CCNC | 2913.0 |
| TCF12 | 2918.0 |
| PAK1 | 2920.0 |
| H2BC12 | 2936.0 |
| NCOA3 | 2940.0 |
| CAPN1 | 2973.0 |
| EPHB3 | 2979.0 |
| LGI4 | 3009.0 |
| MED23 | 3037.0 |
| CEBPD | 3042.0 |
| SPTBN5 | 3061.0 |
| ITGAV | 3093.0 |
| ARPC5 | 3103.0 |
| ANK3 | 3140.0 |
| FOXO3 | 3150.0 |
| AP2M1 | 3156.0 |
| ELOC | 3168.0 |
| CACNA1S | 3195.0 |
| CAP1 | 3198.0 |
| CEBPB | 3224.0 |
| ARPC3 | 3227.0 |
| KRTAP23-1 | 3260.0 |
| HMGCR | 3277.0 |
| RPS20 | 3296.0 |
| TUBB8 | 3302.0 |
| PRX | 3321.0 |
| EIF4A3 | 3324.0 |
| KRT27 | 3327.0 |
| DEK | 3351.0 |
| PSMD2 | 3383.0 |
| AP2A1 | 3402.0 |
| EIF4G1 | 3425.0 |
| FGF9 | 3432.0 |
| PSMC6 | 3448.0 |
| MED27 | 3487.0 |
| RPS15 | 3520.0 |
| RPL24 | 3534.0 |
| DRAP1 | 3576.0 |
| RGMA | 3598.0 |
| RPS6KA5 | 3633.0 |
| RPS3A | 3653.0 |
| CAPNS1 | 3656.0 |
| MEF2C | 3665.0 |
| MED13 | 3675.0 |
| KRT74 | 3685.0 |
| ZNF638 | 3794.0 |
| SPTBN4 | 3808.0 |
| NAB1 | 3869.0 |
| TSC22D1 | 3879.0 |
| JUN | 3936.0 |
| HDAC3 | 3966.0 |
| EP300 | 3970.0 |
| FAM120B | 3992.0 |
| NCAM1 | 4007.0 |
| ACVR2A | 4018.0 |
| KRTAP3-1 | 4021.0 |
| CACNG2 | 4041.0 |
| NR2F2 | 4083.0 |
| DOK6 | 4085.0 |
| ASH2L | 4178.0 |
| NUMB | 4179.0 |
| RPL23 | 4201.0 |
| SUZ12 | 4220.0 |
| KRTAP4-5 | 4234.0 |
| CACNA1H | 4259.0 |
| SMAD2 | 4260.0 |
| COL6A1 | 4268.0 |
| ZFPM2 | 4295.0 |
| PLXND1 | 4322.0 |
| RNPS1 | 4327.0 |
| CUL2 | 4353.0 |
| UBA52 | 4371.0 |
| KRT1 | 4388.0 |
| RPL34 | 4400.0 |
| H2AC4 | 4441.0 |
| CDK8 | 4461.0 |
| SPRR1A | 4463.0 |
| GRB10 | 4487.0 |
| CASC3 | 4491.0 |
| CLASP2 | 4501.0 |
| IRS2 | 4506.0 |
| KRTAP4-2 | 4562.0 |
| KRT19 | 4610.0 |
| EVPL | 4613.0 |
| SOS1 | 4627.0 |
| HELZ2 | 4690.0 |
| PITPNA | 4701.0 |
| LCE1E | 4721.0 |
| WNT4 | 4739.0 |
| COL3A1 | 4740.0 |
| H3C10 | 4749.0 |
| PPARGC1A | 4753.0 |
| SPTBN1 | 4810.0 |
| DOK4 | 4854.0 |
| SH3GL2 | 4871.0 |
| SEMA4D | 4882.0 |
| TBL1XR1 | 4893.0 |
| RHOA | 4928.0 |
| COL6A2 | 4956.0 |
| BNIP2 | 4961.0 |
| KRT73 | 5018.0 |
| PSMC1 | 5036.0 |
| KCNQ2 | 5057.0 |
| NR5A1 | 5061.0 |
| KRT35 | 5091.0 |
| CLTB | 5121.0 |
| RPL4 | 5158.0 |
| ABLIM2 | 5163.0 |
| COL9A2 | 5178.0 |
| TUBB2B | 5220.0 |
| DSG3 | 5239.0 |
| KRT75 | 5260.0 |
| FGF10 | 5313.0 |
| H4C3 | 5331.0 |
| KRT84 | 5352.0 |
| GFRA1 | 5370.0 |
| PFN2 | 5379.0 |
| SALL1 | 5440.0 |
| NKX6-1 | 5441.0 |
| PSMD7 | 5490.0 |
| H4C4 | 5517.0 |
| CARM1 | 5520.0 |
| TFDP2 | 5529.0 |
| KRTAP3-3 | 5554.0 |
| TRPC6 | 5557.0 |
| EPHB6 | 5581.0 |
| SOX9 | 5642.0 |
| DSC2 | 5697.0 |
| KRT18 | 5715.0 |
| DSP | 5721.0 |
| EPHB4 | 5811.0 |
| KLK13 | 5820.0 |
| KRTAP10-3 | 5840.0 |
| PTF1A | 5857.0 |
| MYH11 | 5880.0 |
| EPHA5 | 5890.0 |
| CACNB1 | 5903.0 |
| NCOA1 | 5925.0 |
| USP33 | 5938.0 |
| EFNA2 | 5959.0 |
| HOXA4 | 5997.0 |
| NCOR2 | 6009.0 |
| KRT6B | 6019.0 |
| AKT2 | 6057.0 |
| EPHA1 | 6064.0 |
| EPHA7 | 6067.0 |
| COL6A6 | 6075.0 |
| DLG1 | 6080.0 |
| AP2A2 | 6101.0 |
| H4C16 | 6148.0 |
| H4C11 | 6170.0 |
| SMAD4 | 6230.0 |
| KRT10 | 6237.0 |
| EPHA3 | 6254.0 |
| MMP2 | 6283.0 |
| KMT2C | 6289.0 |
| NGEF | 6310.0 |
| PSMF1 | 6349.0 |
| TFDP1 | 6381.0 |
| HDAC2 | 6411.0 |
| CTNNA1 | 6428.0 |
| YY1 | 6457.0 |
| KMT2D | 6479.0 |
| DSC1 | 6497.0 |
| TUBB1 | 6551.0 |
| DAG1 | 6558.0 |
| H4C13 | 6594.0 |
| MED10 | 6606.0 |
| RPL10L | 6655.0 |
| GATA2 | 6658.0 |
| KRTAP10-10 | 6674.0 |
| SOS2 | 6675.0 |
| KLF4 | 6687.0 |
| KRTAP19-6 | 6714.0 |
| FOXA2 | 6747.0 |
| CNOT6 | 6801.0 |
| FOXA1 | 6862.0 |
| DKK1 | 6888.0 |
| HHEX | 6891.0 |
| H2BC9 | 6991.5 |
| H3C7 | 6991.5 |
| HOXB1 | 7027.0 |
| MED16 | 7052.0 |
| CREB1 | 7072.0 |
| H2AX | 7107.0 |
| KRTAP10-8 | 7121.0 |
| ZSWIM8 | 7126.0 |
| KRT77 | 7142.0 |
| KRTAP13-2 | 7143.0 |
| FURIN | 7145.0 |
| MED7 | 7150.0 |
| RPL27 | 7151.0 |
| TAL1 | 7194.0 |
| CDSN | 7222.0 |
| SMAD3 | 7232.0 |
| FABP4 | 7300.0 |
| SPAG9 | 7330.0 |
| HOXB2 | 7387.0 |
| AKT1 | 7464.0 |
| SLC2A2 | 7473.0 |
| SREBF1 | 7540.0 |
| KRT79 | 7555.0 |
| GFRA4 | 7577.0 |
| H3C3 | 7600.0 |
| PKP3 | 7649.0 |
| NOTCH1 | 7710.0 |
| RPL26 | 7721.0 |
| PIP5K1C | 7722.0 |
| TUBA3C | 7743.0 |
| CER1 | 7752.0 |
| RPL22 | 7815.0 |
| LCE2B | 7825.0 |
| PTPRA | 7840.0 |
| KRT4 | 7981.0 |
| NRTN | 7988.0 |
| PCGF2 | 7999.0 |
| PLXNA1 | 8000.0 |
| KAT2B | 8009.0 |
| POLR2A | 8039.0 |
| FRS2 | 8052.0 |
| MED18 | 8070.0 |
| AKAP5 | 8148.0 |
| PSMA8 | 8189.0 |
| SCN4A | 8241.0 |
| KRTAP1-1 | 8296.0 |
| PSPN | 8333.0 |
| KRTAP10-6 | 8341.0 |
| LCE5A | 8406.0 |
| PAK4 | 8420.0 |
| KRTAP19-2 | 8433.0 |
| HOXB4 | 8450.0 |
| KRTAP17-1 | 8496.0 |
| FLG | 8545.0 |
| PKLR | 8548.0 |
| LEFTY1 | 8557.0 |
| TCF3 | 8579.0 |
| KRTAP10-12 | 8606.0 |
| KRT37 | 8633.0 |
| RELA | 8703.0 |
| KRTAP6-1 | 8711.0 |
| KRTAP10-1 | 8745.0 |
| WDR5 | 8800.0 |
| H2BC15 | 8813.0 |
| KRTAP4-8 | 8816.0 |
| KRT71 | 8830.0 |
| LELP1 | 8840.0 |
| KRTAP4-4 | 8845.0 |
| ITGA10 | 8918.0 |
| KRTAP2-3 | 8990.0 |
| LCE3D | 9036.0 |
| PRNP | 9043.0 |
| SRGAP2 | 9048.0 |
| SNAI1 | 9070.0 |
| KRTAP19-8 | 9121.0 |
| TUBA3E | 9124.0 |
| RPL3L | 9151.0 |
| PRKACG | 9172.0 |
| MED30 | 9271.0 |
| LIPK | 9272.0 |
| KRTAP12-2 | 9297.0 |
| KRTAP5-2 | 9343.0 |
| POLR2J | 9345.0 |
| HOXB3 | 9397.0 |
REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE
| 271 | |
|---|---|
| set | REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE |
| setSize | 105 |
| pANOVA | 0.001 |
| s.dist | -0.186 |
| p.adjustANOVA | 0.183 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL35A | -11731 |
| RPL12 | -11317 |
| TRAM1 | -11310 |
| SRP9 | -11211 |
| RPL10A | -10960 |
| SEC61B | -10682 |
| RPL23A | -10666 |
| RPS13 | -10627 |
| RPL18 | -10404 |
| RPL35 | -10232 |
| RPL8 | -9570 |
| RPL30 | -9564 |
| RPS8 | -9372 |
| SRP72 | -9247 |
| RPS23 | -9186 |
| RPL3 | -9036 |
| RPL37 | -9016 |
| RPLP2 | -8901 |
| RPS27A | -8850 |
| SPCS1 | -8736 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL35A | -11731.0 |
| RPL12 | -11317.0 |
| TRAM1 | -11310.0 |
| SRP9 | -11211.0 |
| RPL10A | -10960.0 |
| SEC61B | -10682.0 |
| RPL23A | -10666.0 |
| RPS13 | -10627.0 |
| RPL18 | -10404.0 |
| RPL35 | -10232.0 |
| RPL8 | -9570.0 |
| RPL30 | -9564.0 |
| RPS8 | -9372.0 |
| SRP72 | -9247.0 |
| RPS23 | -9186.0 |
| RPL3 | -9036.0 |
| RPL37 | -9016.0 |
| RPLP2 | -8901.0 |
| RPS27A | -8850.0 |
| SPCS1 | -8736.0 |
| SEC61G | -8395.0 |
| RPL36 | -8324.0 |
| RPS10 | -8127.0 |
| RPN1 | -8112.0 |
| RPS15A | -7940.0 |
| RPS18 | -7899.0 |
| RPS6 | -7875.0 |
| SSR1 | -7720.0 |
| RPL27A | -7502.0 |
| RPL7 | -7346.0 |
| RPS25 | -7128.0 |
| RPL41 | -7109.0 |
| RPL15 | -6931.0 |
| SEC61A1 | -6708.0 |
| RPS2 | -6644.0 |
| RPS14 | -6614.0 |
| SEC11A | -6485.0 |
| RPL17 | -6404.0 |
| RPS27 | -6385.0 |
| RPL38 | -6209.0 |
| RPS7 | -6174.0 |
| RPL28 | -5935.0 |
| RPLP0 | -5821.0 |
| RPS24 | -5735.0 |
| RPL13 | -5315.0 |
| RPL21 | -5078.0 |
| SRP54 | -5063.0 |
| RPS3 | -4929.0 |
| RPL11 | -4567.0 |
| RPS26 | -4458.0 |
| SSR2 | -4404.0 |
| RPL9 | -4316.0 |
| RPLP1 | -4306.0 |
| FAU | -4024.0 |
| SPCS2 | -3893.0 |
| RPS11 | -3891.0 |
| RPL39L | -3705.0 |
| RPL18A | -3568.0 |
| RPL31 | -3185.0 |
| RPL36AL | -3061.5 |
| RPL6 | -3002.0 |
| SRP14 | -2981.0 |
| SPCS3 | -2825.0 |
| DDOST | -2258.0 |
| RPL5 | -2041.0 |
| RPL29 | -2004.0 |
| RPL13A | -1763.5 |
| SEC11C | -1576.0 |
| RPL14 | -1458.0 |
| RPS29 | -1284.0 |
| RPL37A | -1041.0 |
| RPL22L1 | -925.0 |
| RPL7A | -848.0 |
| RPS28 | -820.0 |
| RPS19 | -560.0 |
| RPL19 | -351.0 |
| RPS5 | -141.0 |
| RPS21 | 432.0 |
| RPS27L | 478.0 |
| RPS16 | 492.0 |
| RPL32 | 844.0 |
| RPL26L1 | 1044.0 |
| RPN2 | 1322.0 |
| SRP19 | 1413.0 |
| SRPRA | 1427.0 |
| RPS12 | 1537.0 |
| RPSA | 1951.0 |
| SRPRB | 2418.0 |
| RPS9 | 2453.0 |
| SRP68 | 2954.0 |
| SSR3 | 3114.0 |
| RPS20 | 3296.0 |
| RPS15 | 3520.0 |
| RPL24 | 3534.0 |
| RPS3A | 3653.0 |
| RPL23 | 4201.0 |
| UBA52 | 4371.0 |
| RPL34 | 4400.0 |
| RPL4 | 5158.0 |
| RPL10L | 6655.0 |
| RPL27 | 7151.0 |
| SEC61A2 | 7159.0 |
| RPL26 | 7721.0 |
| RPL22 | 7815.0 |
| RPL3L | 9151.0 |
REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ACETYLATION
| 1070 | |
|---|---|
| set | REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ACETYLATION |
| setSize | 29 |
| pANOVA | 0.0012 |
| s.dist | 0.347 |
| p.adjustANOVA | 0.197 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| HDAC1 | 8951 |
| PIP4K2B | 7570 |
| ING5 | 7528 |
| AKT1 | 7464 |
| BRPF1 | 6789 |
| CHD3 | 6769 |
| HDAC2 | 6411 |
| AKT2 | 6057 |
| BRPF3 | 5709 |
| MBD3 | 5014 |
| TP53 | 4288 |
| PIN1 | 4069 |
| EP300 | 3970 |
| BRD1 | 3378 |
| CHD4 | 3141 |
| BRD7 | 2550 |
| KAT6A | 2327 |
| AKT3 | 2190 |
| ING2 | 474 |
| PIP4K2C | 85 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| HDAC1 | 8951 |
| PIP4K2B | 7570 |
| ING5 | 7528 |
| AKT1 | 7464 |
| BRPF1 | 6789 |
| CHD3 | 6769 |
| HDAC2 | 6411 |
| AKT2 | 6057 |
| BRPF3 | 5709 |
| MBD3 | 5014 |
| TP53 | 4288 |
| PIN1 | 4069 |
| EP300 | 3970 |
| BRD1 | 3378 |
| CHD4 | 3141 |
| BRD7 | 2550 |
| KAT6A | 2327 |
| AKT3 | 2190 |
| ING2 | 474 |
| PIP4K2C | 85 |
| MAP2K6 | -317 |
| MEAF6 | -812 |
| PML | -996 |
| GATAD2B | -1799 |
| MTA2 | -2680 |
| PIP4P1 | -3230 |
| RBBP4 | -3719 |
| GATAD2A | -5799 |
| PIP4K2A | -6221 |
REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS
| 1364 | |
|---|---|
| set | REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS |
| setSize | 161 |
| pANOVA | 0.00139 |
| s.dist | -0.146 |
| p.adjustANOVA | 0.208 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| HOXA2 | -12116 |
| RPL35A | -11731 |
| RPL12 | -11317 |
| PSMB7 | -11240 |
| RPL10A | -10960 |
| RPL23A | -10666 |
| PSMD13 | -10647 |
| RPS13 | -10627 |
| MAGOHB | -10533 |
| RPL18 | -10404 |
| RPL35 | -10232 |
| PSMC5 | -9926 |
| NCBP1 | -9863 |
| PSMB3 | -9639 |
| RPL8 | -9570 |
| RPL30 | -9564 |
| LHX9 | -9411 |
| RPS8 | -9372 |
| RPS23 | -9186 |
| PSMC4 | -9044 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| HOXA2 | -12116.0 |
| RPL35A | -11731.0 |
| RPL12 | -11317.0 |
| PSMB7 | -11240.0 |
| RPL10A | -10960.0 |
| RPL23A | -10666.0 |
| PSMD13 | -10647.0 |
| RPS13 | -10627.0 |
| MAGOHB | -10533.0 |
| RPL18 | -10404.0 |
| RPL35 | -10232.0 |
| PSMC5 | -9926.0 |
| NCBP1 | -9863.0 |
| PSMB3 | -9639.0 |
| RPL8 | -9570.0 |
| RPL30 | -9564.0 |
| LHX9 | -9411.0 |
| RPS8 | -9372.0 |
| RPS23 | -9186.0 |
| PSMC4 | -9044.0 |
| RPL3 | -9036.0 |
| PSMB4 | -9031.0 |
| RPL37 | -9016.0 |
| RPLP2 | -8901.0 |
| RPS27A | -8850.0 |
| LDB1 | -8818.0 |
| PSME2 | -8655.0 |
| PSMC2 | -8605.0 |
| PSMC3 | -8583.0 |
| PSMB8 | -8422.0 |
| RPL36 | -8324.0 |
| RPS10 | -8127.0 |
| SLIT1 | -8025.0 |
| PSMB1 | -7961.0 |
| RPS15A | -7940.0 |
| RPS18 | -7899.0 |
| RPS6 | -7875.0 |
| PSMD11 | -7679.0 |
| PSMD12 | -7653.0 |
| UBC | -7516.0 |
| RPL27A | -7502.0 |
| RPL7 | -7346.0 |
| MAGOH | -7338.0 |
| LHX2 | -7312.0 |
| PSMA1 | -7186.0 |
| RPS25 | -7128.0 |
| RPL41 | -7109.0 |
| RPL15 | -6931.0 |
| RPS2 | -6644.0 |
| RPS14 | -6614.0 |
| UBB | -6558.0 |
| RBX1 | -6489.0 |
| PSMD4 | -6474.0 |
| RPL17 | -6404.0 |
| RPS27 | -6385.0 |
| RPL38 | -6209.0 |
| RBM8A | -6194.0 |
| RPS7 | -6174.0 |
| PSMB5 | -6101.0 |
| PSMB9 | -5962.0 |
| RPL28 | -5935.0 |
| RPLP0 | -5821.0 |
| PSMA7 | -5784.0 |
| RPS24 | -5735.0 |
| PSMD3 | -5582.0 |
| RPL13 | -5315.0 |
| PSMA4 | -5279.0 |
| PSMB11 | -5123.0 |
| RPL21 | -5078.0 |
| PSMA2 | -5037.0 |
| NCBP2 | -4990.0 |
| RPS3 | -4929.0 |
| RPL11 | -4567.0 |
| RPS26 | -4458.0 |
| PSMB10 | -4396.0 |
| GSPT1 | -4335.0 |
| RPL9 | -4316.0 |
| PSME4 | -4311.0 |
| RPLP1 | -4306.0 |
| PSMA6 | -4225.0 |
| FAU | -4024.0 |
| RPS11 | -3891.0 |
| RPL39L | -3705.0 |
| RPL18A | -3568.0 |
| RPL31 | -3185.0 |
| RPL36AL | -3061.5 |
| PSMD8 | -3004.0 |
| RPL6 | -3002.0 |
| ROBO1 | -2800.0 |
| PSMD9 | -2679.0 |
| ELOB | -2654.0 |
| ETF1 | -2365.0 |
| PSMD1 | -2198.0 |
| RPL5 | -2041.0 |
| RPL29 | -2004.0 |
| UPF2 | -1846.0 |
| RPL13A | -1763.5 |
| RPL14 | -1458.0 |
| ROBO3 | -1355.0 |
| ROBO2 | -1298.0 |
| RPS29 | -1284.0 |
| RPL37A | -1041.0 |
| PSMD14 | -968.0 |
| RPL22L1 | -925.0 |
| LHX4 | -892.0 |
| RPL7A | -848.0 |
| RPS28 | -820.0 |
| RPS19 | -560.0 |
| RPL19 | -351.0 |
| MSI1 | -248.0 |
| PABPC1 | -207.0 |
| RPS5 | -141.0 |
| PSMD5 | 47.0 |
| RPS21 | 432.0 |
| RPS27L | 478.0 |
| RPS16 | 492.0 |
| PSMA3 | 761.0 |
| RPL32 | 844.0 |
| UPF3A | 966.0 |
| RPL26L1 | 1044.0 |
| PSMD6 | 1244.0 |
| RPS12 | 1537.0 |
| PSME3 | 1619.0 |
| RPSA | 1951.0 |
| SEM1 | 1961.0 |
| PSMB2 | 2057.0 |
| RPS9 | 2453.0 |
| PSMA5 | 2542.0 |
| PSME1 | 2636.0 |
| PSMB6 | 2700.0 |
| LHX3 | 2744.0 |
| ISL1 | 2773.0 |
| SLIT2 | 2865.0 |
| ELOC | 3168.0 |
| RPS20 | 3296.0 |
| EIF4A3 | 3324.0 |
| PSMD2 | 3383.0 |
| EIF4G1 | 3425.0 |
| PSMC6 | 3448.0 |
| RPS15 | 3520.0 |
| RPL24 | 3534.0 |
| RPS3A | 3653.0 |
| RPL23 | 4201.0 |
| RNPS1 | 4327.0 |
| CUL2 | 4353.0 |
| UBA52 | 4371.0 |
| RPL34 | 4400.0 |
| CASC3 | 4491.0 |
| PSMC1 | 5036.0 |
| RPL4 | 5158.0 |
| PSMD7 | 5490.0 |
| USP33 | 5938.0 |
| PSMF1 | 6349.0 |
| DAG1 | 6558.0 |
| RPL10L | 6655.0 |
| ZSWIM8 | 7126.0 |
| RPL27 | 7151.0 |
| RPL26 | 7721.0 |
| RPL22 | 7815.0 |
| PSMA8 | 8189.0 |
| RPL3L | 9151.0 |
REACTOME_NERVOUS_SYSTEM_DEVELOPMENT
| 1536 | |
|---|---|
| set | REACTOME_NERVOUS_SYSTEM_DEVELOPMENT |
| setSize | 552 |
| pANOVA | 0.00166 |
| s.dist | -0.0783 |
| p.adjustANOVA | 0.228 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TREM2 | -12299 |
| HOXA2 | -12116 |
| TYROBP | -12086 |
| SCN11A | -11792 |
| RPL35A | -11731 |
| SEMA4A | -11328 |
| RPL12 | -11317 |
| RRAS | -11267 |
| GFRA3 | -11247 |
| PSMB7 | -11240 |
| RHOB | -11238 |
| SCN2B | -11183 |
| DSCAML1 | -11093 |
| MMP9 | -11092 |
| SCN4B | -11024 |
| RPL10A | -10960 |
| MAPK12 | -10918 |
| NRAS | -10906 |
| COL5A1 | -10699 |
| RPL23A | -10666 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TREM2 | -12299.0 |
| HOXA2 | -12116.0 |
| TYROBP | -12086.0 |
| SCN11A | -11792.0 |
| RPL35A | -11731.0 |
| SEMA4A | -11328.0 |
| RPL12 | -11317.0 |
| RRAS | -11267.0 |
| GFRA3 | -11247.0 |
| PSMB7 | -11240.0 |
| RHOB | -11238.0 |
| SCN2B | -11183.0 |
| DSCAML1 | -11093.0 |
| MMP9 | -11092.0 |
| SCN4B | -11024.0 |
| RPL10A | -10960.0 |
| MAPK12 | -10918.0 |
| NRAS | -10906.0 |
| COL5A1 | -10699.0 |
| RPL23A | -10666.0 |
| PSMD13 | -10647.0 |
| RPS13 | -10627.0 |
| MAGOHB | -10533.0 |
| SHTN1 | -10463.0 |
| RPL18 | -10404.0 |
| CACNA1C | -10343.0 |
| PLXNB1 | -10321.0 |
| RPL35 | -10232.0 |
| SCN8A | -10207.0 |
| AP2S1 | -10172.0 |
| ARPC4 | -10108.0 |
| ACTB | -10011.0 |
| MYL12A | -9990.0 |
| MAPK13 | -9948.0 |
| PLXNA2 | -9934.0 |
| PSMC5 | -9926.0 |
| NTN1 | -9920.0 |
| ACTG1 | -9912.0 |
| GRB2 | -9911.0 |
| MPZ | -9881.0 |
| PTPRC | -9874.0 |
| NCBP1 | -9863.0 |
| PPP3CB | -9853.0 |
| TUBA4A | -9708.0 |
| PSMB3 | -9639.0 |
| ITGA5 | -9630.0 |
| RPL8 | -9570.0 |
| RPL30 | -9564.0 |
| ARHGEF11 | -9516.0 |
| LHX9 | -9411.0 |
| ITGA9 | -9379.0 |
| RPS8 | -9372.0 |
| CRMP1 | -9358.0 |
| LYPLA2 | -9342.0 |
| CLTCL1 | -9266.0 |
| UNC5B | -9254.0 |
| SPTBN2 | -9204.0 |
| COL4A3 | -9201.0 |
| MET | -9188.0 |
| RPS23 | -9186.0 |
| PSMC4 | -9044.0 |
| RPL3 | -9036.0 |
| PSMB4 | -9031.0 |
| RPL37 | -9016.0 |
| CDK5 | -8961.0 |
| TUBAL3 | -8959.0 |
| RPLP2 | -8901.0 |
| RPS27A | -8850.0 |
| CAP2 | -8848.0 |
| LDB1 | -8818.0 |
| PMP22 | -8815.0 |
| ARPC2 | -8781.0 |
| NFASC | -8740.0 |
| GAB2 | -8677.0 |
| PSME2 | -8655.0 |
| ADGRV1 | -8612.0 |
| PSMC2 | -8605.0 |
| PSMC3 | -8583.0 |
| TUBB4B | -8578.0 |
| FLRT3 | -8491.0 |
| TIAM1 | -8442.0 |
| PSMB8 | -8422.0 |
| RDX | -8338.0 |
| RPL36 | -8324.0 |
| YAP1 | -8303.0 |
| SEMA7A | -8270.0 |
| TUBB2A | -8245.0 |
| RPS10 | -8127.0 |
| COL2A1 | -8080.0 |
| SRGAP3 | -8052.0 |
| SLIT1 | -8025.0 |
| KALRN | -7964.0 |
| PSMB1 | -7961.0 |
| LAMB1 | -7960.0 |
| ABLIM3 | -7947.0 |
| RPS15A | -7940.0 |
| FGFR1 | -7913.0 |
| RPS18 | -7899.0 |
| PRKAR2A | -7893.0 |
| RPS6 | -7875.0 |
| EFNA1 | -7822.0 |
| CDC42 | -7738.0 |
| SLIT3 | -7727.0 |
| SRC | -7717.0 |
| SCN2A | -7700.0 |
| PSMD11 | -7679.0 |
| PRKACA | -7677.0 |
| PSMD12 | -7653.0 |
| FARP2 | -7636.0 |
| CSNK2A2 | -7627.0 |
| RAP1GAP | -7617.0 |
| CACNB4 | -7597.0 |
| CACNA1D | -7568.0 |
| NRP2 | -7518.0 |
| UBC | -7516.0 |
| RPL27A | -7502.0 |
| CNTN6 | -7444.0 |
| GAP43 | -7356.0 |
| RPL7 | -7346.0 |
| COL9A3 | -7344.0 |
| MAGOH | -7338.0 |
| DPYSL3 | -7317.0 |
| LHX2 | -7312.0 |
| PTK2 | -7305.0 |
| DOK2 | -7250.0 |
| PSMA1 | -7186.0 |
| EFNB3 | -7184.0 |
| RPS25 | -7128.0 |
| RPL41 | -7109.0 |
| SREBF2 | -7045.0 |
| SIAH2 | -7035.0 |
| CSNK2A1 | -7031.0 |
| RPL15 | -6931.0 |
| VAV2 | -6903.0 |
| MAPK11 | -6815.0 |
| ST8SIA2 | -6777.0 |
| RHOC | -6770.0 |
| SCN5A | -6727.0 |
| SEMA3E | -6723.0 |
| CNTNAP1 | -6713.0 |
| RET | -6690.0 |
| RPS2 | -6644.0 |
| TEAD1 | -6640.0 |
| RPS14 | -6614.0 |
| UBB | -6558.0 |
| NCAN | -6547.0 |
| SPTB | -6517.0 |
| SCN3A | -6493.0 |
| RBX1 | -6489.0 |
| PSMD4 | -6474.0 |
| NAB2 | -6468.0 |
| ITSN1 | -6429.0 |
| RPL17 | -6404.0 |
| RPS27 | -6385.0 |
| SPTA1 | -6367.0 |
| CFL1 | -6343.0 |
| GAB1 | -6306.0 |
| PIK3CA | -6283.0 |
| ST8SIA4 | -6280.0 |
| RPL38 | -6209.0 |
| RBM8A | -6194.0 |
| RPS7 | -6174.0 |
| PRKACB | -6133.0 |
| PSMB5 | -6101.0 |
| ALCAM | -6062.0 |
| PIK3R2 | -6034.0 |
| SCN10A | -6013.0 |
| DLG4 | -5964.0 |
| PSMB9 | -5962.0 |
| RPL28 | -5935.0 |
| GRB7 | -5849.0 |
| RPLP0 | -5821.0 |
| PSMA7 | -5784.0 |
| RPS24 | -5735.0 |
| PIK3R1 | -5692.0 |
| PAK6 | -5653.0 |
| RAC1 | -5651.0 |
| RANBP9 | -5587.0 |
| DNM2 | -5584.0 |
| PSMD3 | -5582.0 |
| PAK5 | -5551.0 |
| SHC3 | -5542.0 |
| CXCR4 | -5539.0 |
| GRIN1 | -5535.0 |
| PSEN1 | -5526.0 |
| GRIN2B | -5523.0 |
| MYL9 | -5455.0 |
| PFN1 | -5408.0 |
| COL5A2 | -5407.0 |
| UNC5A | -5374.0 |
| AGRN | -5326.0 |
| RPL13 | -5315.0 |
| PSMA4 | -5279.0 |
| LAMA2 | -5227.0 |
| DPYSL2 | -5142.0 |
| PSMB11 | -5123.0 |
| RPL21 | -5078.0 |
| PSMA2 | -5037.0 |
| MAG | -5021.0 |
| NCBP2 | -4990.0 |
| RELN | -4972.0 |
| DPYSL5 | -4948.0 |
| RPS3 | -4929.0 |
| CLTA | -4928.0 |
| ERBB2 | -4838.0 |
| GSK3B | -4830.0 |
| DPYSL4 | -4723.0 |
| EZR | -4698.0 |
| ITGB3 | -4662.0 |
| TUBA1B | -4626.0 |
| CNTN1 | -4616.0 |
| MAP2K1 | -4569.0 |
| RPL11 | -4567.0 |
| SEMA5A | -4559.0 |
| RPS26 | -4458.0 |
| TRPC7 | -4442.0 |
| ANK1 | -4426.0 |
| MYH14 | -4399.0 |
| PSMB10 | -4396.0 |
| GSPT1 | -4335.0 |
| CSNK2B | -4328.0 |
| RPL9 | -4316.0 |
| PSME4 | -4311.0 |
| RPLP1 | -4306.0 |
| PSMA6 | -4225.0 |
| ADAM10 | -4196.0 |
| TRPC3 | -4188.0 |
| EPHB2 | -4089.0 |
| CACNA1I | -4081.0 |
| COL5A3 | -4080.0 |
| TUBA4B | -4076.0 |
| MYO10 | -4070.0 |
| TRIO | -4048.0 |
| FAU | -4024.0 |
| RPS11 | -3891.0 |
| SCN3B | -3845.0 |
| LIMK1 | -3755.0 |
| NRCAM | -3733.0 |
| COL4A2 | -3720.0 |
| RPL39L | -3705.0 |
| MAPK14 | -3702.0 |
| ANK2 | -3638.0 |
| RPL18A | -3568.0 |
| ABL1 | -3561.0 |
| PLXNA4 | -3466.0 |
| PSENEN | -3417.0 |
| CD72 | -3415.0 |
| PRKCA | -3400.0 |
| POU3F1 | -3373.0 |
| ENAH | -3289.0 |
| DSCAM | -3256.0 |
| SOX10 | -3201.0 |
| MYH9 | -3191.0 |
| RPL31 | -3185.0 |
| TLN1 | -3177.0 |
| SEMA3A | -3147.0 |
| RPL36AL | -3061.5 |
| COL6A5 | -3050.0 |
| WASL | -3046.0 |
| PSMD8 | -3004.0 |
| RPL6 | -3002.0 |
| MBP | -2900.0 |
| EPHA2 | -2865.0 |
| PRKCQ | -2828.0 |
| ROBO1 | -2800.0 |
| CDK5R1 | -2738.0 |
| PSMD9 | -2679.0 |
| ELOB | -2654.0 |
| PIK3R3 | -2629.0 |
| SRGAP1 | -2619.0 |
| SDC2 | -2611.0 |
| PSEN2 | -2603.0 |
| DOK1 | -2596.0 |
| DOCK1 | -2571.0 |
| CXCL12 | -2561.0 |
| NCSTN | -2455.0 |
| LAMC1 | -2430.0 |
| VLDLR | -2384.0 |
| ETF1 | -2365.0 |
| ARTN | -2241.0 |
| PSMD1 | -2198.0 |
| RPL5 | -2041.0 |
| ADGRG6 | -2030.0 |
| RPL29 | -2004.0 |
| HJV | -1992.0 |
| ROCK2 | -1985.0 |
| NELL2 | -1967.0 |
| ACTR3 | -1924.0 |
| UPF2 | -1846.0 |
| SHC1 | -1802.0 |
| CACNB3 | -1775.0 |
| GPC1 | -1766.0 |
| RPL13A | -1763.5 |
| CACNB2 | -1742.0 |
| WWTR1 | -1718.0 |
| MAPK1 | -1683.0 |
| PLXNC1 | -1630.0 |
| FES | -1620.0 |
| EPHA8 | -1572.0 |
| CACNA1G | -1482.0 |
| SIAH1 | -1475.0 |
| RPL14 | -1458.0 |
| UNC5C | -1444.0 |
| KIF4B | -1413.0 |
| PIK3CD | -1404.0 |
| ROBO3 | -1355.0 |
| COL4A1 | -1338.0 |
| SCN1A | -1337.0 |
| ARPC1A | -1335.0 |
| ROBO2 | -1298.0 |
| RPS29 | -1284.0 |
| MAP2K2 | -1193.0 |
| FYN | -1185.0 |
| UTRN | -1155.0 |
| SCD5 | -1152.0 |
| TUBB3 | -1149.0 |
| RPS6KA1 | -1101.0 |
| HSP90AA1 | -1097.0 |
| PLCG1 | -1095.0 |
| EVL | -1083.0 |
| DCC | -1048.0 |
| RPL37A | -1041.0 |
| PSMD14 | -968.0 |
| POU3F2 | -944.0 |
| RPL22L1 | -925.0 |
| DNM1 | -921.0 |
| LHX4 | -892.0 |
| EFNA4 | -851.0 |
| RPL7A | -848.0 |
| RPS28 | -820.0 |
| TUBA8 | -738.0 |
| NCK2 | -689.0 |
| EPHA6 | -655.0 |
| TUBA1C | -627.0 |
| HSP90AB1 | -579.0 |
| RPS19 | -560.0 |
| DOK5 | -546.0 |
| CYP51A1 | -486.0 |
| TUBA1A | -478.0 |
| ACTR2 | -466.0 |
| GDNF | -431.0 |
| AGAP2 | -396.0 |
| MYH10 | -356.0 |
| RPL19 | -351.0 |
| MSI1 | -248.0 |
| PABPC1 | -207.0 |
| RPS5 | -141.0 |
| TUBB6 | 10.0 |
| ITGA2 | 11.0 |
| APH1B | 45.0 |
| PSMD5 | 47.0 |
| CLTC | 93.0 |
| KRAS | 94.0 |
| COL6A3 | 112.0 |
| ARHGAP35 | 124.0 |
| VASP | 155.0 |
| MYL6 | 238.0 |
| ITGA1 | 280.0 |
| SCN1B | 311.0 |
| TRPC1 | 354.0 |
| RPS21 | 432.0 |
| HRAS | 462.0 |
| RPS27L | 478.0 |
| RPS16 | 492.0 |
| CLASP1 | 573.0 |
| MAPK8 | 717.0 |
| ARHGAP39 | 719.0 |
| EGFR | 756.0 |
| PSMA3 | 761.0 |
| GIT1 | 794.0 |
| EPHA4 | 795.0 |
| RPL32 | 844.0 |
| EFNA5 | 850.0 |
| LAMA1 | 860.0 |
| TUBB4A | 911.0 |
| NRP1 | 922.0 |
| ARHGEF28 | 934.0 |
| ROCK1 | 965.0 |
| UPF3A | 966.0 |
| UNC5D | 976.0 |
| LIMK2 | 1020.0 |
| RPL26L1 | 1044.0 |
| ITGA2B | 1047.0 |
| TRPC4 | 1054.0 |
| ARHGEF7 | 1055.0 |
| MAPK7 | 1074.0 |
| MAPK3 | 1159.0 |
| EGR2 | 1164.0 |
| RPS6KA2 | 1176.0 |
| PSMD6 | 1244.0 |
| PAK2 | 1282.0 |
| SDCBP | 1329.0 |
| RPS6KA4 | 1345.0 |
| KCNQ3 | 1412.0 |
| ARPC1B | 1507.0 |
| EFNB2 | 1532.0 |
| RPS12 | 1537.0 |
| NCK1 | 1544.0 |
| SEMA6D | 1576.0 |
| PSME3 | 1619.0 |
| HSPA8 | 1683.0 |
| RASA1 | 1724.0 |
| RGMB | 1743.0 |
| CHL1 | 1768.0 |
| SEMA6A | 1769.0 |
| GFRA2 | 1772.0 |
| COL9A1 | 1799.0 |
| ITGB1 | 1812.0 |
| ARHGEF12 | 1846.0 |
| SPTAN1 | 1882.0 |
| ABLIM1 | 1929.0 |
| RPSA | 1951.0 |
| SEM1 | 1961.0 |
| CNTN2 | 1987.0 |
| DNM3 | 2004.0 |
| VAV3 | 2014.0 |
| COL4A4 | 2015.0 |
| NEO1 | 2040.0 |
| PSMB2 | 2057.0 |
| EPHA10 | 2098.0 |
| TUBA3D | 2121.0 |
| EPHB1 | 2125.0 |
| NTN4 | 2175.0 |
| PTPN11 | 2193.0 |
| SCN9A | 2241.0 |
| APH1A | 2359.0 |
| PIK3CB | 2393.0 |
| EFNA3 | 2426.0 |
| RPS9 | 2453.0 |
| MYO9B | 2511.0 |
| PSMA5 | 2542.0 |
| SCN7A | 2545.0 |
| SMARCA4 | 2567.0 |
| PDLIM7 | 2572.0 |
| MYL12B | 2612.0 |
| PSME1 | 2636.0 |
| DAB1 | 2652.0 |
| ABL2 | 2659.0 |
| PSMB6 | 2700.0 |
| LHX3 | 2744.0 |
| ISL1 | 2773.0 |
| AP2B1 | 2792.0 |
| LYN | 2809.0 |
| RND1 | 2848.0 |
| SLIT2 | 2865.0 |
| YES1 | 2889.0 |
| PAK1 | 2920.0 |
| EPHB3 | 2979.0 |
| SPTBN5 | 3061.0 |
| ITGAV | 3093.0 |
| ARPC5 | 3103.0 |
| ANK3 | 3140.0 |
| AP2M1 | 3156.0 |
| ELOC | 3168.0 |
| CACNA1S | 3195.0 |
| CAP1 | 3198.0 |
| ARPC3 | 3227.0 |
| HMGCR | 3277.0 |
| RPS20 | 3296.0 |
| TUBB8 | 3302.0 |
| PRX | 3321.0 |
| EIF4A3 | 3324.0 |
| PSMD2 | 3383.0 |
| AP2A1 | 3402.0 |
| EIF4G1 | 3425.0 |
| PSMC6 | 3448.0 |
| RPS15 | 3520.0 |
| RPL24 | 3534.0 |
| RGMA | 3598.0 |
| RPS6KA5 | 3633.0 |
| RPS3A | 3653.0 |
| SPTBN4 | 3808.0 |
| NAB1 | 3869.0 |
| NCAM1 | 4007.0 |
| DOK6 | 4085.0 |
| NUMB | 4179.0 |
| RPL23 | 4201.0 |
| CACNA1H | 4259.0 |
| COL6A1 | 4268.0 |
| PLXND1 | 4322.0 |
| RNPS1 | 4327.0 |
| CUL2 | 4353.0 |
| UBA52 | 4371.0 |
| RPL34 | 4400.0 |
| GRB10 | 4487.0 |
| CASC3 | 4491.0 |
| CLASP2 | 4501.0 |
| IRS2 | 4506.0 |
| SOS1 | 4627.0 |
| PITPNA | 4701.0 |
| COL3A1 | 4740.0 |
| SPTBN1 | 4810.0 |
| DOK4 | 4854.0 |
| SH3GL2 | 4871.0 |
| SEMA4D | 4882.0 |
| RHOA | 4928.0 |
| COL6A2 | 4956.0 |
| PSMC1 | 5036.0 |
| KCNQ2 | 5057.0 |
| CLTB | 5121.0 |
| RPL4 | 5158.0 |
| ABLIM2 | 5163.0 |
| COL9A2 | 5178.0 |
| TUBB2B | 5220.0 |
| GFRA1 | 5370.0 |
| PFN2 | 5379.0 |
| PSMD7 | 5490.0 |
| TRPC6 | 5557.0 |
| EPHB6 | 5581.0 |
| EPHB4 | 5811.0 |
| MYH11 | 5880.0 |
| EPHA5 | 5890.0 |
| CACNB1 | 5903.0 |
| USP33 | 5938.0 |
| EFNA2 | 5959.0 |
| EPHA1 | 6064.0 |
| EPHA7 | 6067.0 |
| COL6A6 | 6075.0 |
| DLG1 | 6080.0 |
| AP2A2 | 6101.0 |
| EPHA3 | 6254.0 |
| MMP2 | 6283.0 |
| NGEF | 6310.0 |
| PSMF1 | 6349.0 |
| HDAC2 | 6411.0 |
| TUBB1 | 6551.0 |
| DAG1 | 6558.0 |
| RPL10L | 6655.0 |
| SOS2 | 6675.0 |
| CREB1 | 7072.0 |
| ZSWIM8 | 7126.0 |
| RPL27 | 7151.0 |
| GFRA4 | 7577.0 |
| RPL26 | 7721.0 |
| PIP5K1C | 7722.0 |
| TUBA3C | 7743.0 |
| RPL22 | 7815.0 |
| PTPRA | 7840.0 |
| NRTN | 7988.0 |
| PLXNA1 | 8000.0 |
| FRS2 | 8052.0 |
| AKAP5 | 8148.0 |
| PSMA8 | 8189.0 |
| SCN4A | 8241.0 |
| PSPN | 8333.0 |
| PAK4 | 8420.0 |
| ITGA10 | 8918.0 |
| PRNP | 9043.0 |
| SRGAP2 | 9048.0 |
| TUBA3E | 9124.0 |
| RPL3L | 9151.0 |
| PRKACG | 9172.0 |
REACTOME_MTOR_SIGNALLING
| 199 | |
|---|---|
| set | REACTOME_MTOR_SIGNALLING |
| setSize | 40 |
| pANOVA | 0.0022 |
| s.dist | 0.28 |
| p.adjustANOVA | 0.277 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TSC2 | 8343 |
| PRKAA2 | 7672 |
| AKT1 | 7464 |
| YWHAB | 7438 |
| AKT1S1 | 6886 |
| RPTOR | 6730 |
| STK11 | 6647 |
| MTOR | 6285 |
| PRKAG3 | 6061 |
| AKT2 | 6057 |
| CAB39 | 5988 |
| PRKAB1 | 5077 |
| LAMTOR3 | 4577 |
| FKBP1A | 4142 |
| RPS6KB1 | 3984 |
| TSC1 | 3972 |
| EIF4G1 | 3425 |
| EEF2K | 3344 |
| PRKAG2 | 3279 |
| LAMTOR4 | 2978 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TSC2 | 8343 |
| PRKAA2 | 7672 |
| AKT1 | 7464 |
| YWHAB | 7438 |
| AKT1S1 | 6886 |
| RPTOR | 6730 |
| STK11 | 6647 |
| MTOR | 6285 |
| PRKAG3 | 6061 |
| AKT2 | 6057 |
| CAB39 | 5988 |
| PRKAB1 | 5077 |
| LAMTOR3 | 4577 |
| FKBP1A | 4142 |
| RPS6KB1 | 3984 |
| TSC1 | 3972 |
| EIF4G1 | 3425 |
| EEF2K | 3344 |
| PRKAG2 | 3279 |
| LAMTOR4 | 2978 |
| SLC38A9 | 2917 |
| PRKAA1 | 1528 |
| LAMTOR5 | 1049 |
| RRAGA | 333 |
| LAMTOR1 | 215 |
| RHEB | -181 |
| PRKAG1 | -424 |
| EIF4EBP1 | -463 |
| LAMTOR2 | -845 |
| MLST8 | -872 |
| STRADB | -1082 |
| CAB39L | -1091 |
| EIF4B | -1368 |
| STRADA | -2628 |
| PPM1A | -5403 |
| PRKAB2 | -5450 |
| RRAGD | -7024 |
| RRAGC | -7535 |
| RPS6 | -7875 |
| EIF4E | -8547 |
REACTOME_COMPLEMENT_CASCADE
| 212 | |
|---|---|
| set | REACTOME_COMPLEMENT_CASCADE |
| setSize | 54 |
| pANOVA | 0.00261 |
| s.dist | -0.237 |
| p.adjustANOVA | 0.306 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CPN1 | -12180 |
| C5AR2 | -11914 |
| C8B | -11623 |
| FCN2 | -11116 |
| CFHR5 | -10898 |
| C5 | -10844 |
| C8A | -10569 |
| FCN3 | -10405 |
| MBL2 | -9794 |
| C4BPA | -9653 |
| C2 | -9536 |
| CR1 | -9360 |
| C1QA | -9271 |
| CR2 | -8588 |
| GZMM | -8167 |
| C7 | -8008 |
| ELANE | -7850 |
| C1QC | -7269 |
| C5AR1 | -6869 |
| CPB2 | -6812 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CPN1 | -12180.0 |
| C5AR2 | -11914.0 |
| C8B | -11623.0 |
| FCN2 | -11116.0 |
| CFHR5 | -10898.0 |
| C5 | -10844.0 |
| C8A | -10569.0 |
| FCN3 | -10405.0 |
| MBL2 | -9794.0 |
| C4BPA | -9653.0 |
| C2 | -9536.0 |
| CR1 | -9360.0 |
| C1QA | -9271.0 |
| CR2 | -8588.0 |
| GZMM | -8167.0 |
| C7 | -8008.0 |
| ELANE | -7850.0 |
| C1QC | -7269.0 |
| C5AR1 | -6869.0 |
| CPB2 | -6812.0 |
| CRP | -6729.0 |
| CD55 | -6560.0 |
| C1S | -6102.0 |
| VTN | -5914.0 |
| COLEC10 | -5739.0 |
| CD46 | -5362.0 |
| CD59 | -4936.0 |
| C4BPB | -4653.0 |
| C6 | -4374.0 |
| F2 | -4275.0 |
| CLU | -4204.0 |
| SERPING1 | -4072.0 |
| COLEC11 | -2954.0 |
| C9 | -2114.0 |
| CFB | -1927.0 |
| CFHR4 | -1678.0 |
| CFI | -1553.0 |
| C1QB | -1375.0 |
| CFD | -969.0 |
| FCN1 | -340.0 |
| C4A | -13.5 |
| C4B | -13.5 |
| CFHR2 | 520.0 |
| MASP1 | 1503.0 |
| MASP2 | 1838.0 |
| PROS1 | 2314.0 |
| CD81 | 2666.0 |
| CFH | 3256.0 |
| C8G | 3882.0 |
| C3 | 3889.0 |
| C1R | 5971.0 |
| CD19 | 6744.0 |
| CPN2 | 7444.0 |
| C3AR1 | 8829.0 |
REACTOME_REGULATION_OF_PTEN_GENE_TRANSCRIPTION
| 1298 | |
|---|---|
| set | REACTOME_REGULATION_OF_PTEN_GENE_TRANSCRIPTION |
| setSize | 59 |
| pANOVA | 0.00319 |
| s.dist | 0.222 |
| p.adjustANOVA | 0.349 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| SNAI1 | 9070 |
| HDAC1 | 8951 |
| PHC1 | 8944 |
| CBX6 | 8883 |
| CBX2 | 6998 |
| MTA1 | 6936 |
| CHD3 | 6769 |
| RPTOR | 6730 |
| SCMH1 | 6613 |
| HDAC2 | 6411 |
| MTOR | 6285 |
| ATF2 | 5884 |
| BMI1 | 5690 |
| SNAI2 | 5157 |
| MBD3 | 5014 |
| LAMTOR3 | 4577 |
| TP53 | 4288 |
| SUZ12 | 4220 |
| HDAC3 | 3966 |
| RING1 | 3961 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SNAI1 | 9070 |
| HDAC1 | 8951 |
| PHC1 | 8944 |
| CBX6 | 8883 |
| CBX2 | 6998 |
| MTA1 | 6936 |
| CHD3 | 6769 |
| RPTOR | 6730 |
| SCMH1 | 6613 |
| HDAC2 | 6411 |
| MTOR | 6285 |
| ATF2 | 5884 |
| BMI1 | 5690 |
| SNAI2 | 5157 |
| MBD3 | 5014 |
| LAMTOR3 | 4577 |
| TP53 | 4288 |
| SUZ12 | 4220 |
| HDAC3 | 3966 |
| RING1 | 3961 |
| JUN | 3936 |
| KDM1A | 3915 |
| CHD4 | 3141 |
| LAMTOR4 | 2978 |
| SLC38A9 | 2917 |
| MTA3 | 2133 |
| HDAC5 | 1328 |
| MAPK3 | 1159 |
| LAMTOR5 | 1049 |
| EED | 676 |
| RRAGA | 333 |
| LAMTOR1 | 215 |
| HDAC7 | 107 |
| MAF1 | 7 |
| RHEB | -181 |
| MECOM | -608 |
| RNF2 | -618 |
| LAMTOR2 | -845 |
| MLST8 | -872 |
| ATN1 | -955 |
| MAPK1 | -1683 |
| GATAD2B | -1799 |
| RCOR1 | -2598 |
| CBX8 | -2612 |
| MTA2 | -2680 |
| PHC2 | -2749 |
| PTEN | -3066 |
| NR2E1 | -3299 |
| RBBP4 | -3719 |
| EGR1 | -4536 |
| PPARG | -4640 |
| EZH2 | -5457 |
| CBX4 | -5767 |
| GATAD2A | -5799 |
| SALL4 | -6365 |
| PHC3 | -6665 |
| RRAGD | -7024 |
| RRAGC | -7535 |
| REST | -8014 |
REACTOME_DAP12_INTERACTIONS
| 464 | |
|---|---|
| set | REACTOME_DAP12_INTERACTIONS |
| setSize | 37 |
| pANOVA | 0.00344 |
| s.dist | -0.278 |
| p.adjustANOVA | 0.352 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TREM2 | -12299 |
| CD300LB | -12125 |
| TYROBP | -12086 |
| KLRD1 | -11840 |
| SIGLEC14 | -11654 |
| CLEC5A | -11115 |
| NRAS | -10906 |
| TREM1 | -10744 |
| LCP2 | -10227 |
| GRB2 | -9911 |
| B2M | -9168 |
| SIGLEC15 | -8482 |
| CD300E | -8152 |
| VAV2 | -6903 |
| PIK3CA | -6283 |
| PIK3R2 | -6034 |
| PIK3R1 | -5692 |
| RAC1 | -5651 |
| SYK | -5379 |
| HLA-E | -5359 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TREM2 | -12299 |
| CD300LB | -12125 |
| TYROBP | -12086 |
| KLRD1 | -11840 |
| SIGLEC14 | -11654 |
| CLEC5A | -11115 |
| NRAS | -10906 |
| TREM1 | -10744 |
| LCP2 | -10227 |
| GRB2 | -9911 |
| B2M | -9168 |
| SIGLEC15 | -8482 |
| CD300E | -8152 |
| VAV2 | -6903 |
| PIK3CA | -6283 |
| PIK3R2 | -6034 |
| PIK3R1 | -5692 |
| RAC1 | -5651 |
| SYK | -5379 |
| HLA-E | -5359 |
| KLRK1 | -4600 |
| LCK | -2552 |
| SHC1 | -1802 |
| HLA-B | -1486 |
| GRAP2 | -1248 |
| FYN | -1185 |
| PLCG1 | -1095 |
| KRAS | 94 |
| HRAS | 462 |
| NCR2 | 1871 |
| HLA-C | 2005 |
| VAV3 | 2014 |
| PIK3CB | 2393 |
| LAT | 2546 |
| PLCG2 | 3580 |
| SOS1 | 4627 |
| SIRPB1 | 8404 |
REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION
| 151 | |
|---|---|
| set | REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION |
| setSize | 87 |
| pANOVA | 0.00364 |
| s.dist | -0.18 |
| p.adjustANOVA | 0.352 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL35A | -11731 |
| RPL12 | -11317 |
| RPL10A | -10960 |
| RPL23A | -10666 |
| RPS13 | -10627 |
| EEF1G | -10610 |
| RPL18 | -10404 |
| RPL35 | -10232 |
| RPL8 | -9570 |
| RPL30 | -9564 |
| RPS8 | -9372 |
| RPS23 | -9186 |
| RPL3 | -9036 |
| RPL37 | -9016 |
| RPLP2 | -8901 |
| RPS27A | -8850 |
| EEF1B2 | -8847 |
| EEF1A1 | -8773 |
| RPL36 | -8324 |
| RPS10 | -8127 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL35A | -11731.0 |
| RPL12 | -11317.0 |
| RPL10A | -10960.0 |
| RPL23A | -10666.0 |
| RPS13 | -10627.0 |
| EEF1G | -10610.0 |
| RPL18 | -10404.0 |
| RPL35 | -10232.0 |
| RPL8 | -9570.0 |
| RPL30 | -9564.0 |
| RPS8 | -9372.0 |
| RPS23 | -9186.0 |
| RPL3 | -9036.0 |
| RPL37 | -9016.0 |
| RPLP2 | -8901.0 |
| RPS27A | -8850.0 |
| EEF1B2 | -8847.0 |
| EEF1A1 | -8773.0 |
| RPL36 | -8324.0 |
| RPS10 | -8127.0 |
| RPS15A | -7940.0 |
| RPS18 | -7899.0 |
| RPS6 | -7875.0 |
| RPL27A | -7502.0 |
| RPL7 | -7346.0 |
| RPS25 | -7128.0 |
| RPL41 | -7109.0 |
| RPL15 | -6931.0 |
| RPS2 | -6644.0 |
| RPS14 | -6614.0 |
| RPL17 | -6404.0 |
| RPS27 | -6385.0 |
| RPL38 | -6209.0 |
| RPS7 | -6174.0 |
| EEF1A2 | -5960.0 |
| RPL28 | -5935.0 |
| RPLP0 | -5821.0 |
| RPS24 | -5735.0 |
| RPL13 | -5315.0 |
| RPL21 | -5078.0 |
| RPS3 | -4929.0 |
| RPL11 | -4567.0 |
| RPS26 | -4458.0 |
| RPL9 | -4316.0 |
| RPLP1 | -4306.0 |
| FAU | -4024.0 |
| RPS11 | -3891.0 |
| RPL39L | -3705.0 |
| RPL18A | -3568.0 |
| RPL31 | -3185.0 |
| RPL36AL | -3061.5 |
| RPL6 | -3002.0 |
| RPL5 | -2041.0 |
| RPL29 | -2004.0 |
| RPL13A | -1763.5 |
| RPL14 | -1458.0 |
| RPS29 | -1284.0 |
| RPL37A | -1041.0 |
| RPL22L1 | -925.0 |
| RPL7A | -848.0 |
| RPS28 | -820.0 |
| RPS19 | -560.0 |
| RPL19 | -351.0 |
| RPS5 | -141.0 |
| RPS21 | 432.0 |
| RPS27L | 478.0 |
| RPS16 | 492.0 |
| RPL32 | 844.0 |
| RPL26L1 | 1044.0 |
| RPS12 | 1537.0 |
| RPSA | 1951.0 |
| RPS9 | 2453.0 |
| RPS20 | 3296.0 |
| RPS15 | 3520.0 |
| RPL24 | 3534.0 |
| EEF1D | 3594.0 |
| RPS3A | 3653.0 |
| RPL23 | 4201.0 |
| UBA52 | 4371.0 |
| RPL34 | 4400.0 |
| RPL4 | 5158.0 |
| EEF2 | 6286.0 |
| RPL10L | 6655.0 |
| RPL27 | 7151.0 |
| RPL26 | 7721.0 |
| RPL22 | 7815.0 |
| RPL3L | 9151.0 |
REACTOME_ANTIMICROBIAL_PEPTIDES
| 1060 | |
|---|---|
| set | REACTOME_ANTIMICROBIAL_PEPTIDES |
| setSize | 76 |
| pANOVA | 0.0043 |
| s.dist | -0.189 |
| p.adjustANOVA | 0.373 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| S100A8 | -12422 |
| DEFA4 | -12414 |
| RNASE3 | -12388 |
| CTSG | -12333 |
| S100A7A | -12159 |
| S100A9 | -12138 |
| PGLYRP3 | -11976 |
| GNLY | -11953 |
| CAMP | -11907 |
| BPIFB4 | -11767 |
| DEFB1 | -11692 |
| SEMG1 | -11655 |
| DEFB127 | -11503 |
| RNASE7 | -11477 |
| PI3 | -11389 |
| RNASE8 | -11209 |
| DEFB110 | -11193 |
| LYZ | -11088 |
| LTF | -11083 |
| PGLYRP1 | -11075 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| S100A8 | -12422.0 |
| DEFA4 | -12414.0 |
| RNASE3 | -12388.0 |
| CTSG | -12333.0 |
| S100A7A | -12159.0 |
| S100A9 | -12138.0 |
| PGLYRP3 | -11976.0 |
| GNLY | -11953.0 |
| CAMP | -11907.0 |
| BPIFB4 | -11767.0 |
| DEFB1 | -11692.0 |
| SEMG1 | -11655.0 |
| DEFB127 | -11503.0 |
| RNASE7 | -11477.0 |
| PI3 | -11389.0 |
| RNASE8 | -11209.0 |
| DEFB110 | -11193.0 |
| LYZ | -11088.0 |
| LTF | -11083.0 |
| PGLYRP1 | -11075.0 |
| S100A7 | -10923.0 |
| DEFB125 | -10762.0 |
| DEFB118 | -10201.0 |
| BPIFA2 | -10075.0 |
| BPIFB6 | -10052.0 |
| SLC11A1 | -9944.0 |
| LCN2 | -9600.0 |
| EPPIN-WFDC6 | -9173.0 |
| DEFB133 | -7876.0 |
| BPI | -7862.0 |
| ELANE | -7850.0 |
| DEFB121 | -7228.0 |
| DEFB124 | -6969.0 |
| PLA2G2A | -6966.0 |
| PGLYRP4 | -6540.0 |
| DEFB126 | -5727.0 |
| DEFB136 | -4917.0 |
| PRTN3 | -4641.0 |
| CLU | -4204.0 |
| DEFB129 | -4113.0 |
| HTN3 | -3991.0 |
| DEFB119 | -3918.0 |
| DEFB115 | -3693.0 |
| BPIFB2 | -3337.0 |
| CHGA | -2328.0 |
| CCR6 | -2053.0 |
| PRSS3 | -1098.0 |
| DEFB134 | -657.0 |
| DEFB132 | -450.0 |
| REG3G | -448.0 |
| DEFB114 | -223.0 |
| DEFB116 | -48.0 |
| HTN1 | 374.0 |
| BPIFA1 | 469.0 |
| BPIFB1 | 598.0 |
| TLR1 | 1380.0 |
| ART1 | 2248.0 |
| DCD | 3789.0 |
| REG3A | 4372.0 |
| ATOX1 | 4725.0 |
| EPPIN | 4770.0 |
| DEFB123 | 6800.0 |
| LEAP2 | 6935.0 |
| TLR2 | 7026.0 |
| DEFB104A | 7492.5 |
| DEFB104B | 7492.5 |
| DEFB113 | 7980.0 |
| RNASE6 | 8250.0 |
| DEFA5 | 8324.0 |
| CD4 | 8382.0 |
| DEFB128 | 8594.0 |
| PGLYRP2 | 8958.0 |
| CCR2 | 9046.0 |
| ITLN1 | 9256.0 |
| DEFB135 | 9316.0 |
| DEFA6 | 9331.0 |
REACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_LINKED_TO_LIPOGENESIS
| 1418 | |
|---|---|
| set | REACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_LINKED_TO_LIPOGENESIS |
| setSize | 9 |
| pANOVA | 0.00443 |
| s.dist | 0.548 |
| p.adjustANOVA | 0.373 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| FASN | 8738 |
| SREBF1 | 7540 |
| ANGPTL3 | 6890 |
| NR1H2 | 6444 |
| SCD | 6298 |
| NRIP1 | 5594 |
| RXRB | 4038 |
| RXRA | -1749 |
| NR1H3 | -2472 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| FASN | 8738 |
| SREBF1 | 7540 |
| ANGPTL3 | 6890 |
| NR1H2 | 6444 |
| SCD | 6298 |
| NRIP1 | 5594 |
| RXRB | 4038 |
| RXRA | -1749 |
| NR1H3 | -2472 |
REACTOME_METABOLISM_OF_ANGIOTENSINOGEN_TO_ANGIOTENSINS
| 385 | |
|---|---|
| set | REACTOME_METABOLISM_OF_ANGIOTENSINOGEN_TO_ANGIOTENSINS |
| setSize | 16 |
| pANOVA | 0.00454 |
| s.dist | -0.41 |
| p.adjustANOVA | 0.373 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CTSG | -12333 |
| GZMH | -12041 |
| CPB1 | -11604 |
| CTSZ | -10581 |
| CPA3 | -10320 |
| ACE | -10272 |
| CES1 | -9439 |
| ENPEP | -8406 |
| CTSD | -8389 |
| CPB2 | -6812 |
| AGT | -6001 |
| REN | -1418 |
| ANPEP | -709 |
| MME | 2873 |
| CMA1 | 4605 |
| AOPEP | 5833 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CTSG | -12333 |
| GZMH | -12041 |
| CPB1 | -11604 |
| CTSZ | -10581 |
| CPA3 | -10320 |
| ACE | -10272 |
| CES1 | -9439 |
| ENPEP | -8406 |
| CTSD | -8389 |
| CPB2 | -6812 |
| AGT | -6001 |
| REN | -1418 |
| ANPEP | -709 |
| MME | 2873 |
| CMA1 | 4605 |
| AOPEP | 5833 |
REACTOME_SIGNALING_BY_ROBO_RECEPTORS
| 605 | |
|---|---|
| set | REACTOME_SIGNALING_BY_ROBO_RECEPTORS |
| setSize | 206 |
| pANOVA | 0.00502 |
| s.dist | -0.113 |
| p.adjustANOVA | 0.393 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| HOXA2 | -12116 |
| RPL35A | -11731 |
| RPL12 | -11317 |
| PSMB7 | -11240 |
| RPL10A | -10960 |
| RPL23A | -10666 |
| PSMD13 | -10647 |
| RPS13 | -10627 |
| MAGOHB | -10533 |
| RPL18 | -10404 |
| RPL35 | -10232 |
| PSMC5 | -9926 |
| NTN1 | -9920 |
| NCBP1 | -9863 |
| PPP3CB | -9853 |
| PSMB3 | -9639 |
| RPL8 | -9570 |
| RPL30 | -9564 |
| LHX9 | -9411 |
| RPS8 | -9372 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| HOXA2 | -12116.0 |
| RPL35A | -11731.0 |
| RPL12 | -11317.0 |
| PSMB7 | -11240.0 |
| RPL10A | -10960.0 |
| RPL23A | -10666.0 |
| PSMD13 | -10647.0 |
| RPS13 | -10627.0 |
| MAGOHB | -10533.0 |
| RPL18 | -10404.0 |
| RPL35 | -10232.0 |
| PSMC5 | -9926.0 |
| NTN1 | -9920.0 |
| NCBP1 | -9863.0 |
| PPP3CB | -9853.0 |
| PSMB3 | -9639.0 |
| RPL8 | -9570.0 |
| RPL30 | -9564.0 |
| LHX9 | -9411.0 |
| RPS8 | -9372.0 |
| RPS23 | -9186.0 |
| PSMC4 | -9044.0 |
| RPL3 | -9036.0 |
| PSMB4 | -9031.0 |
| RPL37 | -9016.0 |
| RPLP2 | -8901.0 |
| RPS27A | -8850.0 |
| CAP2 | -8848.0 |
| LDB1 | -8818.0 |
| PSME2 | -8655.0 |
| PSMC2 | -8605.0 |
| PSMC3 | -8583.0 |
| FLRT3 | -8491.0 |
| PSMB8 | -8422.0 |
| RPL36 | -8324.0 |
| RPS10 | -8127.0 |
| SRGAP3 | -8052.0 |
| SLIT1 | -8025.0 |
| PSMB1 | -7961.0 |
| RPS15A | -7940.0 |
| RPS18 | -7899.0 |
| PRKAR2A | -7893.0 |
| RPS6 | -7875.0 |
| CDC42 | -7738.0 |
| SLIT3 | -7727.0 |
| SRC | -7717.0 |
| PSMD11 | -7679.0 |
| PRKACA | -7677.0 |
| PSMD12 | -7653.0 |
| UBC | -7516.0 |
| RPL27A | -7502.0 |
| RPL7 | -7346.0 |
| MAGOH | -7338.0 |
| LHX2 | -7312.0 |
| PSMA1 | -7186.0 |
| RPS25 | -7128.0 |
| RPL41 | -7109.0 |
| RPL15 | -6931.0 |
| RPS2 | -6644.0 |
| RPS14 | -6614.0 |
| UBB | -6558.0 |
| RBX1 | -6489.0 |
| PSMD4 | -6474.0 |
| RPL17 | -6404.0 |
| RPS27 | -6385.0 |
| RPL38 | -6209.0 |
| RBM8A | -6194.0 |
| RPS7 | -6174.0 |
| PRKACB | -6133.0 |
| PSMB5 | -6101.0 |
| PSMB9 | -5962.0 |
| RPL28 | -5935.0 |
| RPLP0 | -5821.0 |
| PSMA7 | -5784.0 |
| RPS24 | -5735.0 |
| PAK6 | -5653.0 |
| RAC1 | -5651.0 |
| PSMD3 | -5582.0 |
| PAK5 | -5551.0 |
| CXCR4 | -5539.0 |
| PFN1 | -5408.0 |
| RPL13 | -5315.0 |
| PSMA4 | -5279.0 |
| PSMB11 | -5123.0 |
| RPL21 | -5078.0 |
| PSMA2 | -5037.0 |
| NCBP2 | -4990.0 |
| RPS3 | -4929.0 |
| RPL11 | -4567.0 |
| RPS26 | -4458.0 |
| PSMB10 | -4396.0 |
| GSPT1 | -4335.0 |
| RPL9 | -4316.0 |
| PSME4 | -4311.0 |
| RPLP1 | -4306.0 |
| PSMA6 | -4225.0 |
| FAU | -4024.0 |
| RPS11 | -3891.0 |
| RPL39L | -3705.0 |
| RPL18A | -3568.0 |
| ABL1 | -3561.0 |
| PRKCA | -3400.0 |
| ENAH | -3289.0 |
| RPL31 | -3185.0 |
| RPL36AL | -3061.5 |
| PSMD8 | -3004.0 |
| RPL6 | -3002.0 |
| ROBO1 | -2800.0 |
| PSMD9 | -2679.0 |
| ELOB | -2654.0 |
| SRGAP1 | -2619.0 |
| CXCL12 | -2561.0 |
| ETF1 | -2365.0 |
| PSMD1 | -2198.0 |
| RPL5 | -2041.0 |
| RPL29 | -2004.0 |
| NELL2 | -1967.0 |
| UPF2 | -1846.0 |
| GPC1 | -1766.0 |
| RPL13A | -1763.5 |
| RPL14 | -1458.0 |
| ROBO3 | -1355.0 |
| ROBO2 | -1298.0 |
| RPS29 | -1284.0 |
| EVL | -1083.0 |
| DCC | -1048.0 |
| RPL37A | -1041.0 |
| PSMD14 | -968.0 |
| RPL22L1 | -925.0 |
| LHX4 | -892.0 |
| RPL7A | -848.0 |
| RPS28 | -820.0 |
| NCK2 | -689.0 |
| RPS19 | -560.0 |
| RPL19 | -351.0 |
| MSI1 | -248.0 |
| PABPC1 | -207.0 |
| RPS5 | -141.0 |
| PSMD5 | 47.0 |
| VASP | 155.0 |
| RPS21 | 432.0 |
| RPS27L | 478.0 |
| RPS16 | 492.0 |
| CLASP1 | 573.0 |
| ARHGAP39 | 719.0 |
| PSMA3 | 761.0 |
| RPL32 | 844.0 |
| NRP1 | 922.0 |
| UPF3A | 966.0 |
| RPL26L1 | 1044.0 |
| PSMD6 | 1244.0 |
| PAK2 | 1282.0 |
| RPS12 | 1537.0 |
| NCK1 | 1544.0 |
| PSME3 | 1619.0 |
| RPSA | 1951.0 |
| SEM1 | 1961.0 |
| PSMB2 | 2057.0 |
| RPS9 | 2453.0 |
| MYO9B | 2511.0 |
| PSMA5 | 2542.0 |
| PSME1 | 2636.0 |
| ABL2 | 2659.0 |
| PSMB6 | 2700.0 |
| LHX3 | 2744.0 |
| ISL1 | 2773.0 |
| SLIT2 | 2865.0 |
| PAK1 | 2920.0 |
| ELOC | 3168.0 |
| CAP1 | 3198.0 |
| RPS20 | 3296.0 |
| EIF4A3 | 3324.0 |
| PSMD2 | 3383.0 |
| EIF4G1 | 3425.0 |
| PSMC6 | 3448.0 |
| RPS15 | 3520.0 |
| RPL24 | 3534.0 |
| RPS3A | 3653.0 |
| RPL23 | 4201.0 |
| RNPS1 | 4327.0 |
| CUL2 | 4353.0 |
| UBA52 | 4371.0 |
| RPL34 | 4400.0 |
| CASC3 | 4491.0 |
| CLASP2 | 4501.0 |
| SOS1 | 4627.0 |
| RHOA | 4928.0 |
| PSMC1 | 5036.0 |
| RPL4 | 5158.0 |
| PFN2 | 5379.0 |
| PSMD7 | 5490.0 |
| USP33 | 5938.0 |
| PSMF1 | 6349.0 |
| DAG1 | 6558.0 |
| RPL10L | 6655.0 |
| SOS2 | 6675.0 |
| ZSWIM8 | 7126.0 |
| RPL27 | 7151.0 |
| RPL26 | 7721.0 |
| RPL22 | 7815.0 |
| AKAP5 | 8148.0 |
| PSMA8 | 8189.0 |
| PAK4 | 8420.0 |
| SRGAP2 | 9048.0 |
| RPL3L | 9151.0 |
| PRKACG | 9172.0 |
REACTOME_BINDING_AND_UPTAKE_OF_LIGANDS_BY_SCAVENGER_RECEPTORS
| 465 | |
|---|---|
| set | REACTOME_BINDING_AND_UPTAKE_OF_LIGANDS_BY_SCAVENGER_RECEPTORS |
| setSize | 42 |
| pANOVA | 0.00533 |
| s.dist | -0.248 |
| p.adjustANOVA | 0.393 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| FTL | -12213 |
| AMBP | -11981 |
| SPARC | -11924 |
| CALR | -11407 |
| CD163 | -11367 |
| MARCO | -11346 |
| HSP90B1 | -11026 |
| APOB | -10737 |
| COLEC12 | -9712 |
| JCHAIN | -9665 |
| HBA1 | -9603 |
| FTH1 | -9258 |
| CD36 | -8750 |
| COL1A1 | -7764 |
| HP | -7374 |
| ALB | -7202 |
| SAA1 | -6701 |
| STAB1 | -6077 |
| APOA1 | -5630 |
| SCARF1 | -5351 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| FTL | -12213 |
| AMBP | -11981 |
| SPARC | -11924 |
| CALR | -11407 |
| CD163 | -11367 |
| MARCO | -11346 |
| HSP90B1 | -11026 |
| APOB | -10737 |
| COLEC12 | -9712 |
| JCHAIN | -9665 |
| HBA1 | -9603 |
| FTH1 | -9258 |
| CD36 | -8750 |
| COL1A1 | -7764 |
| HP | -7374 |
| ALB | -7202 |
| SAA1 | -6701 |
| STAB1 | -6077 |
| APOA1 | -5630 |
| SCARF1 | -5351 |
| SCARB1 | -3942 |
| MSR1 | -3908 |
| COL4A2 | -3720 |
| COLEC11 | -2954 |
| APOE | -2860 |
| LRP1 | -1874 |
| SCARA5 | -1728 |
| COL4A1 | -1338 |
| HSP90AA1 | -1097 |
| SSC5D | -819 |
| HPR | -683 |
| STAB2 | -648 |
| HSPH1 | -323 |
| COL1A2 | 720 |
| MASP1 | 1503 |
| HBA2 | 2106 |
| HPX | 2154 |
| HYOU1 | 2458 |
| HBB | 4410 |
| COL3A1 | 4740 |
| SCGB3A2 | 8688 |
| APOL1 | 9399 |
REACTOME_PROTEIN_METHYLATION
| 1268 | |
|---|---|
| set | REACTOME_PROTEIN_METHYLATION |
| setSize | 17 |
| pANOVA | 0.00551 |
| s.dist | 0.389 |
| p.adjustANOVA | 0.393 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| ETFB | 8837 |
| EEF2KMT | 8389 |
| VCPKMT | 7456 |
| CAMKMT | 6316 |
| EEF2 | 6286 |
| EEF1AKMT2 | 5948 |
| VCP | 5713 |
| PRMT3 | 5111 |
| CALM1 | 4126 |
| EEF1AKMT1 | 3827 |
| METTL22 | 2923 |
| KIN | 2782 |
| METTL21A | 1759 |
| HSPA8 | 1683 |
| RPS2 | -6644 |
| ETFBKMT | -7420 |
| EEF1A1 | -8773 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ETFB | 8837 |
| EEF2KMT | 8389 |
| VCPKMT | 7456 |
| CAMKMT | 6316 |
| EEF2 | 6286 |
| EEF1AKMT2 | 5948 |
| VCP | 5713 |
| PRMT3 | 5111 |
| CALM1 | 4126 |
| EEF1AKMT1 | 3827 |
| METTL22 | 2923 |
| KIN | 2782 |
| METTL21A | 1759 |
| HSPA8 | 1683 |
| RPS2 | -6644 |
| ETFBKMT | -7420 |
| EEF1A1 | -8773 |
REACTOME_NONSENSE_MEDIATED_DECAY_NMD
| 1443 | |
|---|---|
| set | REACTOME_NONSENSE_MEDIATED_DECAY_NMD |
| setSize | 107 |
| pANOVA | 0.00691 |
| s.dist | -0.151 |
| p.adjustANOVA | 0.473 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL35A | -11731 |
| RPL12 | -11317 |
| RPL10A | -10960 |
| RPL23A | -10666 |
| RPS13 | -10627 |
| MAGOHB | -10533 |
| RPL18 | -10404 |
| RPL35 | -10232 |
| SMG9 | -9964 |
| NCBP1 | -9863 |
| RPL8 | -9570 |
| RPL30 | -9564 |
| RPS8 | -9372 |
| RPS23 | -9186 |
| SMG1 | -9165 |
| RPL3 | -9036 |
| RPL37 | -9016 |
| RPLP2 | -8901 |
| RPS27A | -8850 |
| PNRC2 | -8343 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL35A | -11731.0 |
| RPL12 | -11317.0 |
| RPL10A | -10960.0 |
| RPL23A | -10666.0 |
| RPS13 | -10627.0 |
| MAGOHB | -10533.0 |
| RPL18 | -10404.0 |
| RPL35 | -10232.0 |
| SMG9 | -9964.0 |
| NCBP1 | -9863.0 |
| RPL8 | -9570.0 |
| RPL30 | -9564.0 |
| RPS8 | -9372.0 |
| RPS23 | -9186.0 |
| SMG1 | -9165.0 |
| RPL3 | -9036.0 |
| RPL37 | -9016.0 |
| RPLP2 | -8901.0 |
| RPS27A | -8850.0 |
| PNRC2 | -8343.0 |
| RPL36 | -8324.0 |
| RPS10 | -8127.0 |
| UPF1 | -7992.0 |
| RPS15A | -7940.0 |
| RPS18 | -7899.0 |
| RPS6 | -7875.0 |
| RPL27A | -7502.0 |
| RPL7 | -7346.0 |
| MAGOH | -7338.0 |
| RPS25 | -7128.0 |
| RPL41 | -7109.0 |
| RPL15 | -6931.0 |
| PPP2R1A | -6897.0 |
| RPS2 | -6644.0 |
| RPS14 | -6614.0 |
| RPL17 | -6404.0 |
| RPS27 | -6385.0 |
| RPL38 | -6209.0 |
| RBM8A | -6194.0 |
| RPS7 | -6174.0 |
| RPL28 | -5935.0 |
| RPLP0 | -5821.0 |
| RPS24 | -5735.0 |
| RPL13 | -5315.0 |
| RPL21 | -5078.0 |
| NCBP2 | -4990.0 |
| RPS3 | -4929.0 |
| RPL11 | -4567.0 |
| RPS26 | -4458.0 |
| GSPT1 | -4335.0 |
| RPL9 | -4316.0 |
| RPLP1 | -4306.0 |
| FAU | -4024.0 |
| RPS11 | -3891.0 |
| RPL39L | -3705.0 |
| RPL18A | -3568.0 |
| RPL31 | -3185.0 |
| RPL36AL | -3061.5 |
| RPL6 | -3002.0 |
| ETF1 | -2365.0 |
| SMG6 | -2049.0 |
| RPL5 | -2041.0 |
| RPL29 | -2004.0 |
| UPF2 | -1846.0 |
| RPL13A | -1763.5 |
| SMG8 | -1689.0 |
| RPL14 | -1458.0 |
| RPS29 | -1284.0 |
| RPL37A | -1041.0 |
| RPL22L1 | -925.0 |
| RPL7A | -848.0 |
| RPS28 | -820.0 |
| RPS19 | -560.0 |
| SMG7 | -536.0 |
| RPL19 | -351.0 |
| PABPC1 | -207.0 |
| RPS5 | -141.0 |
| RPS21 | 432.0 |
| RPS27L | 478.0 |
| RPS16 | 492.0 |
| RPL32 | 844.0 |
| UPF3A | 966.0 |
| RPL26L1 | 1044.0 |
| RPS12 | 1537.0 |
| PPP2CA | 1705.0 |
| RPSA | 1951.0 |
| RPS9 | 2453.0 |
| RPS20 | 3296.0 |
| EIF4A3 | 3324.0 |
| EIF4G1 | 3425.0 |
| RPS15 | 3520.0 |
| RPL24 | 3534.0 |
| RPS3A | 3653.0 |
| RPL23 | 4201.0 |
| RNPS1 | 4327.0 |
| UBA52 | 4371.0 |
| RPL34 | 4400.0 |
| CASC3 | 4491.0 |
| RPL4 | 5158.0 |
| DCP1A | 5538.0 |
| SMG5 | 6179.0 |
| PPP2R2A | 6269.0 |
| RPL10L | 6655.0 |
| RPL27 | 7151.0 |
| RPL26 | 7721.0 |
| RPL22 | 7815.0 |
| RPL3L | 9151.0 |
REACTOME_REGULATION_OF_TLR_BY_ENDOGENOUS_LIGAND
| 997 | |
|---|---|
| set | REACTOME_REGULATION_OF_TLR_BY_ENDOGENOUS_LIGAND |
| setSize | 21 |
| pANOVA | 0.00737 |
| s.dist | -0.338 |
| p.adjustANOVA | 0.48 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| S100A8 | -12422 |
| S100A9 | -12138 |
| FGA | -12036 |
| FGG | -11862 |
| SFTPA2 | -11779 |
| HMGB1 | -11028 |
| APOB | -10737 |
| CD36 | -8750 |
| TLR6 | -7989 |
| SFTPD | -7570 |
| LBP | -7062 |
| GSDMD | -5447 |
| FGB | -5103 |
| TLR4 | -3591 |
| S100A1 | -2145 |
| GSDME | -899 |
| SFTPA1 | 386 |
| TLR1 | 1380 |
| CD14 | 5065 |
| TLR2 | 7026 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| S100A8 | -12422 |
| S100A9 | -12138 |
| FGA | -12036 |
| FGG | -11862 |
| SFTPA2 | -11779 |
| HMGB1 | -11028 |
| APOB | -10737 |
| CD36 | -8750 |
| TLR6 | -7989 |
| SFTPD | -7570 |
| LBP | -7062 |
| GSDMD | -5447 |
| FGB | -5103 |
| TLR4 | -3591 |
| S100A1 | -2145 |
| GSDME | -899 |
| SFTPA1 | 386 |
| TLR1 | 1380 |
| CD14 | 5065 |
| TLR2 | 7026 |
| LY96 | 8637 |
REACTOME_KERATINIZATION
| 1073 | |
|---|---|
| set | REACTOME_KERATINIZATION |
| setSize | 210 |
| pANOVA | 0.00761 |
| s.dist | -0.107 |
| p.adjustANOVA | 0.48 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| KRTAP19-5 | -12384 |
| SPRR2E | -12351 |
| KRT16 | -12324 |
| SPRR1B | -12173 |
| KRTAP5-6 | -12156 |
| KRT83 | -12115 |
| KRTAP9-9 | -12083 |
| KRTAP5-9 | -11994 |
| KRT2 | -11966 |
| LCE1A | -11944 |
| KRTAP9-6 | -11852 |
| KRTAP4-11 | -11817 |
| KRTAP8-1 | -11785 |
| KRTAP4-6 | -11769 |
| KRT78 | -11755 |
| KRTAP15-1 | -11665 |
| KRTAP9-1 | -11626 |
| KRT33B | -11608 |
| KRTAP1-3 | -11593 |
| KRTAP25-1 | -11576 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| KRTAP19-5 | -12384 |
| SPRR2E | -12351 |
| KRT16 | -12324 |
| SPRR1B | -12173 |
| KRTAP5-6 | -12156 |
| KRT83 | -12115 |
| KRTAP9-9 | -12083 |
| KRTAP5-9 | -11994 |
| KRT2 | -11966 |
| LCE1A | -11944 |
| KRTAP9-6 | -11852 |
| KRTAP4-11 | -11817 |
| KRTAP8-1 | -11785 |
| KRTAP4-6 | -11769 |
| KRT78 | -11755 |
| KRTAP15-1 | -11665 |
| KRTAP9-1 | -11626 |
| KRT33B | -11608 |
| KRTAP1-3 | -11593 |
| KRTAP25-1 | -11576 |
| KRT15 | -11575 |
| KRTAP21-1 | -11550 |
| SPRR2G | -11548 |
| KRT31 | -11521 |
| KRTAP12-4 | -11500 |
| KRTAP16-1 | -11495 |
| KRTAP1-4 | -11436 |
| PKP2 | -11410 |
| KRTAP5-1 | -11409 |
| PI3 | -11389 |
| KRTAP9-3 | -11357 |
| KRTAP9-4 | -11351 |
| KRTAP12-1 | -11307 |
| KRT3 | -11248 |
| KRT80 | -11063 |
| LCE4A | -10962 |
| ST14 | -10739 |
| KRT33A | -10703 |
| LIPN | -10686 |
| KRTAP26-1 | -10449 |
| KRTAP19-3 | -10389 |
| KRTAP2-4 | -10296 |
| KRT72 | -10287 |
| LIPM | -10203 |
| KLK12 | -10161 |
| KRT13 | -10140 |
| KRTAP10-5 | -10107 |
| KRT39 | -10021 |
| KLK8 | -9998 |
| KRTAP5-11 | -9909 |
| KRTAP19-4 | -9895 |
| KRTAP5-4 | -9752 |
| CASP14 | -9683 |
| LCE3B | -9609 |
| KRTAP24-1 | -9146 |
| LCE3A | -8913 |
| KRT23 | -8888 |
| KRTAP20-1 | -8879 |
| TGM1 | -8761 |
| KRT7 | -8557 |
| TGM5 | -8528 |
| KRTAP21-2 | -8479 |
| SPINK5 | -8392 |
| KRTAP11-1 | -8071 |
| SPINK9 | -7943 |
| SPRR2F | -7904 |
| KRT36 | -7602 |
| KRTAP1-5 | -7501 |
| CELA2A | -7449 |
| KRTAP20-2 | -7447 |
| KRT34 | -7167 |
| LCE2C | -7121 |
| KRT9 | -7098 |
| KRTAP2-2 | -7022 |
| SPRR2D | -6989 |
| KRTAP21-3 | -6938 |
| KRT17 | -6818 |
| KRTAP13-3 | -6736 |
| KRTAP9-2 | -6473 |
| KRTAP5-5 | -6407 |
| KRT40 | -6390 |
| KRTAP6-3 | -6295 |
| KRT28 | -6269 |
| KRTAP13-1 | -6157 |
| KRTAP29-1 | -6152 |
| DSG1 | -6110 |
| KRTAP2-1 | -6051 |
| LCE6A | -6022 |
| LCE3E | -5838 |
| KRTAP10-7 | -5807 |
| KLK5 | -5568 |
| RPTN | -5434 |
| KRTAP10-2 | -5305 |
| KRTAP5-3 | -5229 |
| KRT14 | -5114 |
| CSTA | -5056 |
| KRT6C | -5039 |
| KRT6A | -4753 |
| KRTAP22-1 | -4622 |
| TCHH | -4238 |
| KRTAP10-4 | -4139 |
| DSG4 | -4088 |
| KRTAP4-7 | -3641 |
| KRTAP10-11 | -3635 |
| KRTAP19-7 | -3545 |
| KRTAP12-3 | -3431 |
| PERP | -3220 |
| KRTAP19-1 | -3115 |
| KRTAP27-1 | -2722 |
| KRT85 | -2669 |
| SPRR3 | -2641 |
| LCE1C | -2506 |
| PCSK6 | -2404 |
| PKP1 | -2282 |
| LIPJ | -2225 |
| KRT8 | -1842 |
| PKP4 | -1817 |
| KRT12 | -1778 |
| LCE2D | -1326 |
| KRTAP4-1 | -1317 |
| KAZN | -762 |
| PPL | -669 |
| LCE2A | -619 |
| KRT38 | -556 |
| KRTAP5-8 | -381 |
| KRTAP13-4 | -307 |
| KRTAP6-2 | -295 |
| KRT86 | 32 |
| SPRR2A | 115 |
| KRT76 | 277 |
| JUP | 465 |
| KRT81 | 588 |
| KRT26 | 671 |
| SPINK6 | 1212 |
| DSG2 | 1309 |
| KRT25 | 1315 |
| PRSS8 | 1488 |
| KRTAP5-7 | 1606 |
| IVL | 1771 |
| KRTAP3-2 | 1850 |
| KRTAP10-9 | 1930 |
| KRT24 | 1936 |
| LCE1F | 2039 |
| KRTAP5-10 | 2257 |
| DSC3 | 2372 |
| KRT20 | 2408 |
| KRT82 | 2449 |
| KRT32 | 2467 |
| KRT5 | 2604 |
| LCE1B | 2645 |
| KRTAP4-3 | 2779 |
| KLK14 | 2895 |
| CAPN1 | 2973 |
| KRTAP23-1 | 3260 |
| KRT27 | 3327 |
| CAPNS1 | 3656 |
| KRT74 | 3685 |
| KRTAP3-1 | 4021 |
| KRTAP4-5 | 4234 |
| KRT1 | 4388 |
| SPRR1A | 4463 |
| KRTAP4-2 | 4562 |
| KRT19 | 4610 |
| EVPL | 4613 |
| LCE1E | 4721 |
| KRT73 | 5018 |
| KRT35 | 5091 |
| DSG3 | 5239 |
| KRT75 | 5260 |
| KRT84 | 5352 |
| KRTAP3-3 | 5554 |
| DSC2 | 5697 |
| KRT18 | 5715 |
| DSP | 5721 |
| KLK13 | 5820 |
| KRTAP10-3 | 5840 |
| KRT6B | 6019 |
| KRT10 | 6237 |
| DSC1 | 6497 |
| KRTAP10-10 | 6674 |
| KRTAP19-6 | 6714 |
| KRTAP10-8 | 7121 |
| KRT77 | 7142 |
| KRTAP13-2 | 7143 |
| FURIN | 7145 |
| CDSN | 7222 |
| KRT79 | 7555 |
| PKP3 | 7649 |
| LCE2B | 7825 |
| KRT4 | 7981 |
| KRTAP1-1 | 8296 |
| KRTAP10-6 | 8341 |
| LCE5A | 8406 |
| KRTAP19-2 | 8433 |
| KRTAP17-1 | 8496 |
| FLG | 8545 |
| KRTAP10-12 | 8606 |
| KRT37 | 8633 |
| KRTAP6-1 | 8711 |
| KRTAP10-1 | 8745 |
| KRTAP4-8 | 8816 |
| KRT71 | 8830 |
| LELP1 | 8840 |
| KRTAP4-4 | 8845 |
| KRTAP2-3 | 8990 |
| LCE3D | 9036 |
| KRTAP19-8 | 9121 |
| LIPK | 9272 |
| KRTAP12-2 | 9297 |
| KRTAP5-2 | 9343 |
REACTOME_SUMOYLATION
| 531 | |
|---|---|
| set | REACTOME_SUMOYLATION |
| setSize | 179 |
| pANOVA | 0.00841 |
| s.dist | 0.114 |
| p.adjustANOVA | 0.511 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| HDAC1 | 8951 |
| PHC1 | 8944 |
| INCENP | 8805 |
| CTBP1 | 8799 |
| RELA | 8703 |
| BIRC5 | 8613 |
| NSMCE3 | 8392 |
| PCGF2 | 7999 |
| PIAS4 | 7741 |
| BRCA1 | 7712 |
| SUMO3 | 7679 |
| RNF168 | 7582 |
| CBX2 | 6998 |
| MTA1 | 6936 |
| TPR | 6788 |
| CHD3 | 6769 |
| TOP1 | 6669 |
| SCMH1 | 6613 |
| H4C13 | 6594 |
| NR1H2 | 6444 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| HDAC1 | 8951 |
| PHC1 | 8944 |
| INCENP | 8805 |
| CTBP1 | 8799 |
| RELA | 8703 |
| BIRC5 | 8613 |
| NSMCE3 | 8392 |
| PCGF2 | 7999 |
| PIAS4 | 7741 |
| BRCA1 | 7712 |
| SUMO3 | 7679 |
| RNF168 | 7582 |
| CBX2 | 6998 |
| MTA1 | 6936 |
| TPR | 6788 |
| CHD3 | 6769 |
| TOP1 | 6669 |
| SCMH1 | 6613 |
| H4C13 | 6594 |
| NR1H2 | 6444 |
| HDAC2 | 6411 |
| PARP1 | 6374 |
| H4C11 | 6170 |
| H4C16 | 6148 |
| NSMCE1 | 6032 |
| NUP54 | 6026 |
| NCOR2 | 6009 |
| NUP35 | 6001 |
| NCOA1 | 5925 |
| HERC2 | 5818 |
| SP100 | 5802 |
| SMC6 | 5758 |
| BMI1 | 5690 |
| NUP98 | 5680 |
| TOP2A | 5606 |
| NRIP1 | 5594 |
| SATB1 | 5584 |
| H4C4 | 5517 |
| RAE1 | 5365 |
| H4C3 | 5331 |
| HDAC4 | 5193 |
| MDC1 | 5118 |
| NR5A1 | 5061 |
| RPA1 | 4991 |
| PPARGC1A | 4753 |
| SENP5 | 4698 |
| NUP58 | 4589 |
| TP53 | 4288 |
| RORA | 4281 |
| UBE2I | 4247 |
| SUZ12 | 4220 |
| NUP214 | 4043 |
| SATB2 | 4006 |
| EP300 | 3970 |
| RING1 | 3961 |
| PGR | 3941 |
| UBA2 | 3505 |
| PARK7 | 3349 |
| NOP58 | 3245 |
| NUP93 | 2790 |
| DNMT3A | 2749 |
| EID3 | 2597 |
| H4C12 | 1999 |
| CREBBP | 1880 |
| ESR1 | 1879 |
| NUP62 | 1815 |
| WRN | 1603 |
| RANGAP1 | 1571 |
| NSMCE4A | 1458 |
| NCOA2 | 1391 |
| TOP2B | 1376 |
| AAAS | 1069 |
| STAG1 | 948 |
| PCNA | 815 |
| NDC1 | 656 |
| CBX5 | 643 |
| PPARA | 540 |
| RARA | 519 |
| NFKB2 | 477 |
| ING2 | 474 |
| NR3C1 | 344 |
| TRIM28 | 263 |
| HDAC7 | 107 |
| SAE1 | 106 |
| NUP205 | 29 |
| RWDD3 | -111 |
| SENP1 | -286 |
| TOPORS | -303 |
| VHL | -383 |
| SEC13 | -518 |
| NSMCE2 | -529 |
| RNF2 | -618 |
| TRIM27 | -733 |
| POM121 | -856 |
| NUP153 | -882 |
| CDCA8 | -979 |
| PML | -996 |
| HIPK2 | -1007 |
| TDG | -1014 |
| SEH1L | -1075 |
| MDM2 | -1112 |
| NR3C2 | -1226 |
| DAXX | -1259 |
| MRTFA | -1315 |
| TP53BP1 | -1353 |
| RAD21 | -1394 |
| THRB | -1450 |
| L3MBTL2 | -1490 |
| RXRA | -1749 |
| NUP155 | -1759 |
| DNMT3B | -1814 |
| TFAP2A | -1948 |
| NFKBIA | -2009 |
| MITF | -2229 |
| SIN3A | -2444 |
| H4C2 | -2471 |
| NR1H3 | -2472 |
| H4C9 | -2491 |
| FOXL2 | -2547 |
| CBX8 | -2612 |
| NUP42 | -2644 |
| PHC2 | -2749 |
| UHRF2 | -2798 |
| XPC | -2934 |
| MBD1 | -2961 |
| NUP88 | -3139 |
| NUP85 | -3203 |
| NUP210 | -3362 |
| NUP160 | -3424 |
| DDX17 | -3529 |
| PIAS2 | -3569 |
| TFAP2C | -3616 |
| NPM1 | -3666 |
| NR5A2 | -3946 |
| HNRNPK | -3949 |
| RAD52 | -3961 |
| HIC1 | -4031 |
| PIAS1 | -4500 |
| PPARG | -4640 |
| SUMO2 | -4761 |
| SMC3 | -4988 |
| DDX5 | -5120 |
| POM121C | -5125 |
| NR1H4 | -5254 |
| NUP133 | -5301 |
| AURKB | -5330 |
| CDKN2A | -5373 |
| NUP188 | -5382 |
| THRA | -5449 |
| H4C5 | -5492 |
| DNMT1 | -5625 |
| CBX4 | -5767 |
| SMC5 | -5884 |
| SP3 | -5991 |
| XRCC4 | -6265 |
| SAFB | -6565 |
| PHC3 | -6665 |
| BLM | -6759 |
| NUP107 | -6806 |
| NR4A2 | -6959 |
| ZNF350 | -7119 |
| NUP50 | -7647 |
| VDR | -7781 |
| TFAP2B | -7810 |
| NR2C1 | -8380 |
| AURKA | -8497 |
| SUMO1 | -8595 |
| HNRNPC | -8608 |
| NR1I2 | -9180 |
| PIAS3 | -9380 |
| RANBP2 | -9638 |
| NUP43 | -9713 |
| H4C6 | -10210 |
| IKBKE | -10829 |
| H4C1 | -11106 |
| SENP2 | -11365 |
| H4C8 | -11506 |
| NUP37 | -11517 |
| ZNF131 | -11764 |
REACTOME_ACROSOME_REACTION_AND_SPERM_OOCYTE_MEMBRANE_BINDING
| 87 | |
|---|---|
| set | REACTOME_ACROSOME_REACTION_AND_SPERM_OOCYTE_MEMBRANE_BINDING |
| setSize | 6 |
| pANOVA | 0.00973 |
| s.dist | -0.609 |
| p.adjustANOVA | 0.57 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| ACR | -12264 |
| IZUMO1 | -12080 |
| CD9 | -10160 |
| IZUMO2 | -8749 |
| IZUMO3 | -7395 |
| IZUMO4 | 1825 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ACR | -12264 |
| IZUMO1 | -12080 |
| CD9 | -10160 |
| IZUMO2 | -8749 |
| IZUMO3 | -7395 |
| IZUMO4 | 1825 |
REACTOME_ORGANELLE_BIOGENESIS_AND_MAINTENANCE
| 289 | |
|---|---|
| set | REACTOME_ORGANELLE_BIOGENESIS_AND_MAINTENANCE |
| setSize | 277 |
| pANOVA | 0.0106 |
| s.dist | 0.0892 |
| p.adjustANOVA | 0.598 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TUBA3E | 9124 |
| PKD1 | 8488 |
| SSNA1 | 8248 |
| CEP152 | 8204 |
| DYNC2I1 | 8006 |
| CEP131 | 7891 |
| TCTN2 | 7870 |
| HAUS4 | 7799 |
| IFT52 | 7796 |
| ATP5MC2 | 7793 |
| TUBA3C | 7743 |
| KIF24 | 7723 |
| PRKAA2 | 7672 |
| SSTR3 | 7634 |
| ATP5PO | 7370 |
| ATP5PD | 7343 |
| CEP72 | 7114 |
| CCT2 | 7076 |
| CREB1 | 7072 |
| NPHP4 | 7033 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TUBA3E | 9124 |
| PKD1 | 8488 |
| SSNA1 | 8248 |
| CEP152 | 8204 |
| DYNC2I1 | 8006 |
| CEP131 | 7891 |
| TCTN2 | 7870 |
| HAUS4 | 7799 |
| IFT52 | 7796 |
| ATP5MC2 | 7793 |
| TUBA3C | 7743 |
| KIF24 | 7723 |
| PRKAA2 | 7672 |
| SSTR3 | 7634 |
| ATP5PO | 7370 |
| ATP5PD | 7343 |
| CEP72 | 7114 |
| CCT2 | 7076 |
| CREB1 | 7072 |
| NPHP4 | 7033 |
| PCNT | 6774 |
| IFT43 | 6673 |
| DYNC1H1 | 6590 |
| TUBB1 | 6551 |
| DYNLT2B | 6543 |
| DCTN1 | 6373 |
| HAUS1 | 6098 |
| PRKAG3 | 6061 |
| DCTN3 | 5936 |
| NCOA1 | 5925 |
| ATF2 | 5884 |
| DNAJC11 | 5871 |
| IFT74 | 5791 |
| TFAM | 5768 |
| EXOC3 | 5616 |
| MICOS10 | 5561 |
| EXOC2 | 5545 |
| CARM1 | 5520 |
| CDK5RAP2 | 5478 |
| MICOS13 | 5428 |
| EXOC5 | 5383 |
| MARK4 | 5359 |
| PRKAR2B | 5355 |
| MTERF1 | 5242 |
| CEP164 | 5227 |
| TUBB2B | 5220 |
| AKAP9 | 5212 |
| SFI1 | 5204 |
| POLRMT | 5185 |
| PRKAB1 | 5077 |
| INPP5E | 5029 |
| TTBK2 | 5009 |
| CRTC1 | 4918 |
| TBL1XR1 | 4893 |
| IFT80 | 4807 |
| PPARGC1A | 4753 |
| AHI1 | 4722 |
| CEP83 | 4703 |
| BBS7 | 4691 |
| HELZ2 | 4690 |
| DYNC2I2 | 4676 |
| CEP57 | 4653 |
| ATP5F1C | 4564 |
| PAFAH1B1 | 4510 |
| UNC119B | 4417 |
| BBIP1 | 4333 |
| CEP97 | 4282 |
| NRF1 | 4262 |
| TWNK | 4185 |
| TCP1 | 4160 |
| ACTR1A | 4136 |
| CALM1 | 4126 |
| IFT140 | 4042 |
| HAUS5 | 3986 |
| HDAC3 | 3966 |
| PKD2 | 3949 |
| SSBP1 | 3849 |
| ATP5MC3 | 3756 |
| MEF2C | 3665 |
| RAB3IP | 3640 |
| RAB11FIP3 | 3610 |
| B9D1 | 3480 |
| TMEM67 | 3330 |
| TUBB8 | 3302 |
| PRKAG2 | 3279 |
| ACSS2 | 3167 |
| KIF3B | 3092 |
| CHCHD3 | 3083 |
| ARL13B | 2992 |
| CHCHD6 | 2956 |
| IFT88 | 2930 |
| NPHP1 | 2910 |
| EXOC7 | 2820 |
| PLK4 | 2676 |
| NEDD1 | 2492 |
| CEP250 | 2463 |
| CEP41 | 2460 |
| KIFAP3 | 2431 |
| NDE1 | 2400 |
| DYNC2H1 | 2385 |
| SIRT4 | 2261 |
| CRTC3 | 2245 |
| CEP192 | 2152 |
| EXOC4 | 2122 |
| TUBA3D | 2121 |
| NCOR1 | 2075 |
| IFT22 | 2062 |
| CKAP5 | 2046 |
| CCT3 | 1962 |
| USP46 | 1932 |
| BBS2 | 1931 |
| CREBBP | 1880 |
| IFT172 | 1811 |
| CEP162 | 1647 |
| IMMT | 1589 |
| NR1D1 | 1555 |
| RAB11A | 1467 |
| TCTN3 | 1401 |
| NCOA2 | 1391 |
| CRTC2 | 1338 |
| TCTN1 | 1269 |
| CEP290 | 1033 |
| NPHP3 | 998 |
| TFB1M | 988 |
| TUBB4A | 911 |
| EXOC1 | 849 |
| ARL6 | 827 |
| GLUD1 | 649 |
| CC2D2A | 638 |
| FBF1 | 587 |
| CLASP1 | 573 |
| PPARA | 540 |
| ALMS1 | 502 |
| CNGB1 | 445 |
| CNGA4 | 439 |
| NCOA6 | 434 |
| SOD2 | 399 |
| ATP5MF | 369 |
| ODF2 | 358 |
| IFT81 | 283 |
| CEP89 | 228 |
| IFT122 | 198 |
| DCTN2 | 111 |
| TUBB6 | 10 |
| BBS4 | -95 |
| CENPJ | -126 |
| CSNK1D | -196 |
| ATP5F1B | -234 |
| PRKAG1 | -424 |
| TUBA1A | -478 |
| SDCCAG8 | -548 |
| TUBA1C | -627 |
| TUBA8 | -738 |
| MED1 | -765 |
| YWHAE | -881 |
| IFT57 | -914 |
| SMO | -957 |
| GBF1 | -995 |
| ARL3 | -1067 |
| TUBG1 | -1088 |
| HSP90AA1 | -1097 |
| ATP5F1A | -1114 |
| TUBB3 | -1149 |
| CEP43 | -1173 |
| CEP135 | -1250 |
| RPGRIP1L | -1283 |
| ESRRA | -1399 |
| DYNC1I2 | -1405 |
| DYNC2LI1 | -1426 |
| TNPO1 | -1502 |
| PPRC1 | -1575 |
| RXRA | -1749 |
| PCM1 | -1883 |
| MCHR1 | -1991 |
| ATP5MC1 | -2136 |
| CCT4 | -2144 |
| TTC21B | -2157 |
| BBS9 | -2224 |
| ATAT1 | -2248 |
| TGS1 | -2388 |
| TMEM11 | -2447 |
| NEK2 | -2530 |
| MKKS | -2551 |
| TTC8 | -2607 |
| MAPRE1 | -2719 |
| DYNLT2 | -2731 |
| KIF3A | -2796 |
| GABPB1 | -2858 |
| HAUS8 | -3056 |
| CEP76 | -3207 |
| CEP70 | -3284 |
| BBS1 | -3367 |
| ATP5PF | -3671 |
| MAPK14 | -3702 |
| GABPA | -3706 |
| CCT8 | -3865 |
| EXOC6 | -3979 |
| TUBA4B | -4076 |
| KIF17 | -4087 |
| C2CD3 | -4235 |
| HAUS3 | -4258 |
| CEP63 | -4405 |
| TUBA1B | -4626 |
| BBS5 | -4691 |
| IFT46 | -4705 |
| PPARGC1B | -4906 |
| BBS10 | -4974 |
| BBS12 | -5071 |
| CAMK4 | -5199 |
| WDR19 | -5209 |
| CDK1 | -5212 |
| PDE6D | -5429 |
| PRKAB2 | -5450 |
| DYNLRB1 | -5464 |
| CHD9 | -5476 |
| SIRT5 | -5490 |
| CYS1 | -5674 |
| CCP110 | -5698 |
| ALAS1 | -5710 |
| ATP5PB | -5715 |
| LZTFL1 | -5752 |
| CNTRL | -5979 |
| YWHAG | -6009 |
| DYNLL1 | -6011 |
| ATP5ME | -6228 |
| WDR35 | -6300 |
| SCLT1 | -6329 |
| ASAP1 | -6394 |
| DMAC2L | -6418 |
| ARF4 | -6448 |
| TRAF3IP1 | -6499 |
| EXOC8 | -6635 |
| CEP78 | -6803 |
| MAPK11 | -6815 |
| PLK1 | -6830 |
| PPP2R1A | -6897 |
| IQCB1 | -7166 |
| HSPA9 | -7563 |
| PRKACA | -7677 |
| IFT27 | -7741 |
| DYNLRB2 | -7748 |
| B9D2 | -7924 |
| DYNLL2 | -8069 |
| CSNK1E | -8153 |
| CCT5 | -8203 |
| TUBB2A | -8245 |
| ATP5F1E | -8499 |
| TUBB4B | -8578 |
| SAMM50 | -8618 |
| ATP5MG | -8619 |
| CYCS | -8627 |
| MTX2 | -8632 |
| CLUAP1 | -8636 |
| TUBB | -8667 |
| SMARCD3 | -8832 |
| TUBAL3 | -8959 |
| TMEM216 | -9234 |
| RAB8A | -9332 |
| RHO | -9341 |
| DYNLT5 | -9498 |
| TRIP11 | -9507 |
| TUBA4A | -9708 |
| PERM1 | -9961 |
| NINL | -10039 |
| HAUS2 | -10142 |
| KIF3C | -10150 |
| SIRT3 | -10158 |
| TFB2M | -10202 |
| IFT20 | -10237 |
| ATP5F1D | -10791 |
| MKS1 | -10808 |
| MAPK12 | -10918 |
| POLG2 | -11065 |
| MEF2D | -11073 |
| HAUS6 | -11336 |
| IDH2 | -11382 |
| MTX1 | -11557 |
REACTOME_REPRODUCTION
| 114 | |
|---|---|
| set | REACTOME_REPRODUCTION |
| setSize | 136 |
| pANOVA | 0.0115 |
| s.dist | -0.125 |
| p.adjustANOVA | 0.598 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| ACR | -12264.0 |
| IZUMO1 | -12080.0 |
| CATSPER4 | -11903.0 |
| CATSPER3 | -11770.0 |
| H2BC14 | -11709.0 |
| H4C8 | -11506.0 |
| H2AC14 | -11332.0 |
| B4GALT1 | -11324.0 |
| ZP1 | -11255.0 |
| H4C1 | -11106.0 |
| H2AC7 | -11040.5 |
| H2BC7 | -11040.5 |
| OVGP1 | -10916.0 |
| DMC1 | -10841.0 |
| TEX15 | -10761.0 |
| H3C1 | -10687.0 |
| ADAM20 | -10677.0 |
| H3C12 | -10530.0 |
| H3C4 | -10465.0 |
| H4C6 | -10210.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ACR | -12264.0 |
| IZUMO1 | -12080.0 |
| CATSPER4 | -11903.0 |
| CATSPER3 | -11770.0 |
| H2BC14 | -11709.0 |
| H4C8 | -11506.0 |
| H2AC14 | -11332.0 |
| B4GALT1 | -11324.0 |
| ZP1 | -11255.0 |
| H4C1 | -11106.0 |
| H2AC7 | -11040.5 |
| H2BC7 | -11040.5 |
| OVGP1 | -10916.0 |
| DMC1 | -10841.0 |
| TEX15 | -10761.0 |
| H3C1 | -10687.0 |
| ADAM20 | -10677.0 |
| H3C12 | -10530.0 |
| H3C4 | -10465.0 |
| H4C6 | -10210.0 |
| HVCN1 | -10189.0 |
| CATSPER1 | -10173.0 |
| CD9 | -10160.0 |
| RAD50 | -10110.0 |
| H2BC11 | -9747.0 |
| CDK4 | -9680.0 |
| LMNA | -9633.0 |
| RAD51 | -9561.0 |
| H2BC6 | -9394.0 |
| ZP4 | -9385.0 |
| STAG3 | -9365.0 |
| SYCP2 | -8984.0 |
| IZUMO2 | -8749.0 |
| ADAM30 | -8666.0 |
| PSMC3IP | -8576.0 |
| RPA2 | -8285.0 |
| MND1 | -7811.0 |
| H3-3B | -7678.0 |
| H2AZ2 | -7419.0 |
| IZUMO3 | -7395.0 |
| PRDM9 | -7223.0 |
| CATSPERD | -7147.0 |
| H2BC1 | -7004.0 |
| MRE11 | -6761.0 |
| BLM | -6759.0 |
| H2BC5 | -6716.0 |
| RPA3 | -6683.0 |
| TINF2 | -6158.0 |
| BRCA2 | -6067.0 |
| SYCE3 | -5837.0 |
| H2BC3 | -5808.0 |
| LMNB1 | -5771.0 |
| SPO11 | -5738.0 |
| DIDO1 | -5732.0 |
| H2BC26 | -5603.0 |
| H4C5 | -5492.0 |
| H2BC4 | -5269.0 |
| SMC3 | -4988.0 |
| FKBP6 | -4814.0 |
| H2AC20 | -4507.0 |
| TEX12 | -4436.0 |
| H2BC17 | -4265.0 |
| H2AJ | -4124.0 |
| H2AZ1 | -3348.0 |
| ZP3 | -3346.0 |
| CDK2 | -3257.0 |
| KCNU1 | -3114.0 |
| SMC1B | -2884.0 |
| HSPA2 | -2625.0 |
| TERF2IP | -2540.0 |
| SYCE1 | -2527.0 |
| H4C9 | -2491.0 |
| H4C2 | -2471.0 |
| H3C6 | -2432.0 |
| H2BC21 | -2245.0 |
| SPAM1 | -2102.0 |
| SYCE2 | -2021.0 |
| H2AC8 | -1791.0 |
| H3-3A | -1455.0 |
| RAD21 | -1394.0 |
| H3C2 | -1304.0 |
| H2AC6 | -1218.0 |
| RAD51C | -900.0 |
| H3C11 | -834.0 |
| MLH3 | -720.0 |
| H2BC13 | -344.0 |
| SYCP1 | -324.0 |
| H3C8 | -157.0 |
| CATSPERG | 168.0 |
| ATM | 437.0 |
| SUN2 | 491.0 |
| ADAM21 | 516.0 |
| TERF2 | 772.0 |
| CATSPERB | 862.0 |
| TOP3A | 882.0 |
| STAG1 | 948.0 |
| H2BC10 | 1052.0 |
| SYCP3 | 1265.0 |
| H2AC18 | 1298.5 |
| H2AC19 | 1298.5 |
| ZP2 | 1479.0 |
| H2BC8 | 1727.0 |
| IZUMO4 | 1825.0 |
| H4C12 | 1999.0 |
| RBBP8 | 2493.0 |
| H2BC12 | 2936.0 |
| ATR | 3006.0 |
| SYNE1 | 3523.0 |
| POT1 | 3791.0 |
| ACD | 3865.5 |
| NBN | 4116.0 |
| UBE2I | 4247.0 |
| MSH5 | 4397.0 |
| H2AC4 | 4441.0 |
| H3C10 | 4749.0 |
| RPA1 | 4991.0 |
| MSH4 | 5011.0 |
| MLH1 | 5071.0 |
| H4C3 | 5331.0 |
| H4C4 | 5517.0 |
| SYNE2 | 5746.0 |
| H4C16 | 6148.0 |
| H4C11 | 6170.0 |
| H4C13 | 6594.0 |
| TERF1 | 6887.0 |
| H2BC9 | 6991.5 |
| H3C7 | 6991.5 |
| H2AX | 7107.0 |
| SUN1 | 7558.0 |
| H3C3 | 7600.0 |
| BRCA1 | 7712.0 |
| ADAM2 | 8038.0 |
| CATSPER2 | 8785.0 |
| H2BC15 | 8813.0 |
| REC8 | 8817.0 |
| H3-4 | 9174.0 |
REACTOME_MEMBRANE_TRAFFICKING
| 374 | |
|---|---|
| set | REACTOME_MEMBRANE_TRAFFICKING |
| setSize | 603 |
| pANOVA | 0.0119 |
| s.dist | 0.06 |
| p.adjustANOVA | 0.598 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TUBA3E | 9124 |
| KIF2B | 8945 |
| AGPAT3 | 8814 |
| GJC2 | 8733 |
| EPN1 | 8727 |
| ARFGAP1 | 8726 |
| AP1M1 | 8630 |
| RAB35 | 8528 |
| SBF1 | 8482 |
| KDELR3 | 8446 |
| CD4 | 8382 |
| TSC2 | 8343 |
| PLA2G6 | 8321 |
| RHOQ | 8316 |
| COPS8 | 8267 |
| BNIP1 | 8263 |
| RAB13 | 8142 |
| CAPZB | 7965 |
| NSF | 7954 |
| COPS4 | 7952 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TUBA3E | 9124 |
| KIF2B | 8945 |
| AGPAT3 | 8814 |
| GJC2 | 8733 |
| EPN1 | 8727 |
| ARFGAP1 | 8726 |
| AP1M1 | 8630 |
| RAB35 | 8528 |
| SBF1 | 8482 |
| KDELR3 | 8446 |
| CD4 | 8382 |
| TSC2 | 8343 |
| PLA2G6 | 8321 |
| RHOQ | 8316 |
| COPS8 | 8267 |
| BNIP1 | 8263 |
| RAB13 | 8142 |
| CAPZB | 7965 |
| NSF | 7954 |
| COPS4 | 7952 |
| STON1 | 7754 |
| TUBA3C | 7743 |
| F5 | 7740 |
| GAK | 7738 |
| GJD2 | 7737 |
| PIP5K1C | 7722 |
| PRKAA2 | 7672 |
| GJB5 | 7658 |
| MON1B | 7587 |
| RINL | 7482 |
| TRAPPC12 | 7476 |
| GJA9 | 7475 |
| AKT1 | 7464 |
| ARCN1 | 7452 |
| YWHAB | 7438 |
| TACR1 | 7417 |
| SEC22C | 7299 |
| KLC1 | 7267 |
| HGS | 7229 |
| GJA10 | 7180 |
| GOLGA5 | 7177 |
| GJA4 | 7168 |
| RABGAP1 | 7136 |
| RAB11B | 7105 |
| DENND4B | 7044 |
| AP1S1 | 7025 |
| RGP1 | 6963 |
| TMED9 | 6925 |
| SYNJ2 | 6903 |
| TRAPPC2L | 6749 |
| SEC24B | 6712 |
| LDLR | 6682 |
| DENND3 | 6657 |
| TRAPPC11 | 6653 |
| GAPVD1 | 6638 |
| DYNC1H1 | 6590 |
| TUBB1 | 6551 |
| VPS52 | 6548 |
| SCARB2 | 6525 |
| BTC | 6475 |
| TBC1D2 | 6468 |
| RALA | 6465 |
| DAB2 | 6418 |
| DCTN1 | 6373 |
| STAM | 6363 |
| SLC2A8 | 6323 |
| GPS1 | 6293 |
| ULK1 | 6267 |
| YKT6 | 6264 |
| CHMP2A | 6167 |
| COG3 | 6144 |
| MAN2A1 | 6143 |
| TSG101 | 6137 |
| DENND4C | 6132 |
| AP2A2 | 6101 |
| PRKAG3 | 6061 |
| AKT2 | 6057 |
| COPB1 | 5990 |
| VPS37D | 5967 |
| AMPH | 5949 |
| AGFG1 | 5943 |
| DCTN3 | 5936 |
| GOLGA1 | 5912 |
| GOLGB1 | 5906 |
| GORASP1 | 5867 |
| TXNDC5 | 5786 |
| NAPB | 5754 |
| VPS37C | 5745 |
| KIF2C | 5730 |
| TRAPPC1 | 5725 |
| KIF1C | 5691 |
| RAB32 | 5637 |
| EXOC3 | 5616 |
| TBC1D17 | 5596 |
| KIF23 | 5593 |
| EXOC2 | 5545 |
| CHMP4B | 5533 |
| PPP6R1 | 5523 |
| KIF27 | 5518 |
| DENND4A | 5424 |
| DENND1C | 5401 |
| MIA3 | 5396 |
| ARFGAP3 | 5386 |
| EXOC5 | 5383 |
| SNAP23 | 5360 |
| BIN1 | 5334 |
| SAR1B | 5321 |
| SEC31A | 5306 |
| VPS54 | 5301 |
| STAM2 | 5277 |
| LMAN2L | 5245 |
| TUBB2B | 5220 |
| NBAS | 5216 |
| CFTR | 5194 |
| EPS15L1 | 5137 |
| DYNC1I1 | 5126 |
| CLTB | 5121 |
| PRKAB1 | 5077 |
| SEC16A | 5023 |
| TRIP10 | 5006 |
| MYO5A | 4997 |
| SNAP91 | 4978 |
| SEC24A | 4927 |
| SH3GL2 | 4871 |
| ASPSCR1 | 4856 |
| COPE | 4842 |
| TRAPPC9 | 4817 |
| SPTBN1 | 4810 |
| TJP1 | 4706 |
| KIF16B | 4695 |
| IGF2R | 4652 |
| DYNC1LI2 | 4617 |
| GCC2 | 4607 |
| CLINT1 | 4587 |
| PAFAH1B1 | 4510 |
| TRAPPC13 | 4468 |
| UBA52 | 4371 |
| SEC24D | 4330 |
| TRAPPC6B | 4242 |
| TBC1D1 | 4199 |
| KIF25 | 4174 |
| AP1G1 | 4162 |
| CHMP4C | 4151 |
| ACTR1A | 4136 |
| CALM1 | 4126 |
| FCHO1 | 4089 |
| COPB2 | 4087 |
| TBC1D13 | 4086 |
| CHMP7 | 4030 |
| RAB5B | 4015 |
| TBC1D15 | 3981 |
| TSC1 | 3972 |
| ITSN2 | 3939 |
| TBC1D10A | 3923 |
| VTI1A | 3824 |
| GOSR1 | 3818 |
| SPTBN4 | 3808 |
| COPS6 | 3739 |
| PPP6C | 3732 |
| AP4S1 | 3716 |
| CHMP6 | 3655 |
| RAB3IP | 3640 |
| KIF13B | 3631 |
| SNAPIN | 3627 |
| COG1 | 3611 |
| RAB5C | 3602 |
| LMAN2 | 3592 |
| NECAP1 | 3559 |
| AP1B1 | 3542 |
| TFRC | 3539 |
| WNT5A | 3533 |
| TFG | 3522 |
| KIFC1 | 3489 |
| EREG | 3437 |
| AP2A1 | 3402 |
| CYTH2 | 3391 |
| DENND6B | 3304 |
| TUBB8 | 3302 |
| PRKAG2 | 3279 |
| KDELR2 | 3250 |
| ARPC3 | 3227 |
| KIF1B | 3218 |
| BICD1 | 3216 |
| AP2M1 | 3156 |
| COL7A1 | 3153 |
| ANK3 | 3140 |
| AP4E1 | 3138 |
| DCTN4 | 3128 |
| ARPC5 | 3103 |
| KIF3B | 3092 |
| SPTBN5 | 3061 |
| GABARAPL2 | 3005 |
| SYTL1 | 2997 |
| SYNJ1 | 2916 |
| CLVS2 | 2843 |
| EXOC7 | 2820 |
| VAMP2 | 2808 |
| AP2B1 | 2792 |
| REPS1 | 2728 |
| KIF26A | 2726 |
| UBQLN1 | 2717 |
| PACSIN3 | 2715 |
| TRAPPC5 | 2591 |
| MYO6 | 2562 |
| TRAPPC8 | 2464 |
| KIFAP3 | 2431 |
| RHOBTB3 | 2401 |
| COPS3 | 2360 |
| RAB33B | 2340 |
| CPD | 2258 |
| SH3GL1 | 2249 |
| AKT3 | 2190 |
| SNAP29 | 2184 |
| EXOC4 | 2122 |
| TUBA3D | 2121 |
| PPP6R3 | 2097 |
| SH3D19 | 2021 |
| DNM3 | 2004 |
| PUM1 | 1955 |
| RAB14 | 1952 |
| UBAP1 | 1893 |
| TBC1D24 | 1891 |
| SPTAN1 | 1882 |
| SEC22A | 1876 |
| CUX1 | 1818 |
| GJB7 | 1762 |
| INS | 1760 |
| TRAPPC10 | 1739 |
| HSPA8 | 1683 |
| KLC2 | 1648 |
| KIF2A | 1569 |
| CENPE | 1535 |
| DNAJC6 | 1522 |
| AP4M1 | 1518 |
| ANKRD27 | 1468 |
| RAB11A | 1467 |
| VPS37A | 1456 |
| STX18 | 1433 |
| DTNBP1 | 1404 |
| RALGAPB | 1362 |
| MADD | 1318 |
| VPS4A | 1195 |
| ANKRD28 | 1179 |
| COG6 | 1177 |
| PAFAH1B2 | 1161 |
| COPG1 | 1057 |
| HPS1 | 1035 |
| GJA3 | 1034 |
| TGFA | 1018 |
| DCTN5 | 953 |
| RAB10 | 940 |
| GALNT2 | 935 |
| TUBB4A | 911 |
| COPS7B | 907 |
| CLVS1 | 879 |
| EXOC1 | 849 |
| VPS37B | 783 |
| DNASE2 | 774 |
| EGFR | 756 |
| CYTH3 | 745 |
| DVL2 | 739 |
| LDLRAP1 | 711 |
| RAB3GAP2 | 647 |
| AP3B1 | 636 |
| RIN1 | 634 |
| MAN1A2 | 627 |
| COG7 | 545 |
| GJB4 | 498 |
| CHMP3 | 456 |
| RABGEF1 | 449 |
| MIA2 | 410 |
| RAB8B | 396 |
| TPD52 | 375 |
| RAB38 | 341 |
| VAMP8 | 328 |
| SYT1 | 282 |
| MAN2A2 | 251 |
| COPA | 206 |
| GJA8 | 188 |
| DCTN2 | 111 |
| CLTC | 93 |
| AP1S3 | 90 |
| SEC16B | 89 |
| LMAN1 | 58 |
| FCHO2 | 33 |
| TUBB6 | 10 |
| RAB12 | -3 |
| NAA38 | -7 |
| SYT8 | -132 |
| TBC1D14 | -137 |
| ARRB2 | -147 |
| IL7R | -191 |
| CSNK1D | -196 |
| TOR1A | -198 |
| DENND5A | -202 |
| KIFC2 | -237 |
| COG4 | -321 |
| SGIP1 | -322 |
| SCFD1 | -345 |
| PRKAG1 | -424 |
| ACTR2 | -466 |
| SEC24C | -470 |
| TUBA1A | -478 |
| ARFRP1 | -491 |
| SEC13 | -518 |
| COPS7A | -541 |
| DENND1A | -624 |
| TUBA1C | -627 |
| RAB3IL1 | -681 |
| TUBA8 | -738 |
| VAMP4 | -837 |
| HPS4 | -850 |
| STX5 | -852 |
| COG5 | -860 |
| YWHAE | -881 |
| GDI2 | -889 |
| DNM1 | -921 |
| GBF1 | -995 |
| KIAA0319 | -1003 |
| KIF15 | -1049 |
| DENND6A | -1081 |
| ARF3 | -1107 |
| TUBB3 | -1149 |
| DCTN6 | -1156 |
| RAB6A | -1197 |
| CHMP2B | -1276 |
| ARPC1A | -1335 |
| STX17 | -1343 |
| COG8 | -1364 |
| TPD52L1 | -1365 |
| DYNC1I2 | -1405 |
| KIF4B | -1413 |
| USE1 | -1447 |
| VPS53 | -1464 |
| TMF1 | -1533 |
| TBC1D10B | -1544 |
| BLOC1S4 | -1592 |
| SEC23A | -1615 |
| TMED3 | -1665 |
| GNS | -1708 |
| PREB | -1760 |
| GALNT1 | -1813 |
| SYT9 | -1856 |
| SEC23IP | -1867 |
| ACTR3 | -1924 |
| GOLGA2 | -1951 |
| DENND5B | -1962 |
| VPS28 | -1995 |
| KIF6 | -2002 |
| CAPZA2 | -2008 |
| KIF22 | -2023 |
| PAFAH1B3 | -2095 |
| BLOC1S1 | -2167 |
| KIF20B | -2265 |
| MVB12B | -2268 |
| FZD4 | -2284 |
| TBC1D16 | -2311 |
| STXBP3 | -2321 |
| COG2 | -2368 |
| SLC2A4 | -2372 |
| RAB3GAP1 | -2400 |
| KIF26B | -2429 |
| ALS2CL | -2435 |
| CTTN | -2515 |
| OPTN | -2516 |
| TBC1D4 | -2541 |
| ZW10 | -2631 |
| TMED2 | -2634 |
| SYT11 | -2642 |
| EPN2 | -2670 |
| ARF5 | -2674 |
| MYO1C | -2720 |
| KIF3A | -2796 |
| ALPP | -2810 |
| CYTH1 | -2851 |
| CNIH2 | -2907 |
| AP1G2 | -2974 |
| RAB27B | -2984 |
| WASL | -3046 |
| RAB7A | -3074 |
| MAP1LC3B | -3095 |
| KIF9 | -3132 |
| C2CD5 | -3165 |
| KIF21A | -3184 |
| MYH9 | -3191 |
| SEC22B | -3271 |
| SLC18A3 | -3302 |
| COPZ2 | -3391 |
| NAPA | -3441 |
| KIF5B | -3475 |
| MCFD2 | -3501 |
| NAA35 | -3504 |
| RAB3A | -3628 |
| ANK2 | -3638 |
| SCOC | -3669 |
| MAN1C1 | -3735 |
| RABEPK | -3758 |
| TOR1B | -3784 |
| CHRM2 | -3801 |
| VPS4B | -3812 |
| EGF | -3814 |
| ARFGAP2 | -3843 |
| RAB21 | -3892 |
| VPS45 | -3916 |
| EXOC6 | -3979 |
| BET1 | -3981 |
| CHMP4A | -4068 |
| VPS25 | -4069 |
| TUBA4B | -4076 |
| SORT1 | -4091 |
| SNX9 | -4118 |
| TMED10 | -4121 |
| SNF8 | -4191 |
| TRAPPC4 | -4210 |
| AAK1 | -4219 |
| NAPG | -4227 |
| HIP1 | -4232 |
| GJB6 | -4271 |
| DYNC1LI1 | -4284 |
| RAB4A | -4288 |
| KDELR1 | -4302 |
| KIF1A | -4313 |
| YWHAZ | -4382 |
| ANK1 | -4426 |
| RIC1 | -4470 |
| RAB18 | -4479 |
| NECAP2 | -4488 |
| PICALM | -4550 |
| PACSIN1 | -4579 |
| EPS15 | -4613 |
| TUBA1B | -4626 |
| PACSIN2 | -4632 |
| SURF4 | -4668 |
| BLOC1S6 | -4749 |
| SERPINA1 | -4767 |
| ALS2 | -4789 |
| PIK3C2A | -4791 |
| MON1A | -4797 |
| PLIN3 | -4849 |
| CBL | -4883 |
| RINT1 | -4898 |
| CLTA | -4928 |
| CD59 | -4936 |
| LMAN1L | -4944 |
| GJA1 | -4963 |
| DENND1B | -4980 |
| DENND2C | -4992 |
| RACGAP1 | -4993 |
| GJD4 | -5011 |
| BICD2 | -5027 |
| TBC1D7 | -5100 |
| LRP2 | -5105 |
| COPZ1 | -5173 |
| RIN3 | -5263 |
| GJB2 | -5266 |
| YWHAQ | -5292 |
| SNX2 | -5311 |
| GGA2 | -5339 |
| ACBD3 | -5395 |
| PRKAB2 | -5450 |
| SNX18 | -5511 |
| PLA2G4A | -5544 |
| DNM2 | -5584 |
| VPS36 | -5589 |
| RAC1 | -5651 |
| KIF18B | -5667 |
| RALGAPA2 | -5670 |
| TMED7 | -5701 |
| USO1 | -5797 |
| KIF19 | -5903 |
| MVB12A | -5915 |
| KIF18A | -5988 |
| YWHAG | -6009 |
| DYNLL1 | -6011 |
| RAB5A | -6042 |
| GJA5 | -6095 |
| GGA1 | -6121 |
| KIF11 | -6135 |
| RAB1B | -6140 |
| EPGN | -6149 |
| VPS51 | -6159 |
| AP4B1 | -6315 |
| FNBP1 | -6321 |
| STX6 | -6322 |
| GCC1 | -6342 |
| SPTA1 | -6367 |
| SNX5 | -6399 |
| STX4 | -6415 |
| ITSN1 | -6429 |
| KLC3 | -6433 |
| ARF4 | -6448 |
| SPTB | -6517 |
| UBB | -6558 |
| CD55 | -6560 |
| EXOC8 | -6635 |
| GOLIM4 | -6688 |
| GOLGA4 | -6811 |
| RAB30 | -6813 |
| LNPEP | -6886 |
| USP6NL | -6888 |
| CHMP5 | -7077 |
| CNIH1 | -7089 |
| SFN | -7102 |
| VAMP3 | -7218 |
| ARL1 | -7370 |
| CYTH4 | -7383 |
| GJC1 | -7392 |
| SBF2 | -7394 |
| VTA1 | -7441 |
| COPS2 | -7461 |
| AP3S1 | -7472 |
| UBC | -7516 |
| TBC1D20 | -7576 |
| ARFIP2 | -7633 |
| SH3GL3 | -7635 |
| TMEM115 | -7701 |
| SRC | -7717 |
| RAB1A | -7865 |
| STX16 | -7966 |
| KIF12 | -7980 |
| RAB27A | -7993 |
| DENND2B | -8030 |
| DYNLL2 | -8069 |
| GOSR2 | -8091 |
| COPS5 | -8093 |
| COPG2 | -8139 |
| KLC4 | -8155 |
| GJB3 | -8240 |
| TUBB2A | -8245 |
| RABEP1 | -8311 |
| RAB43 | -8398 |
| APP | -8452 |
| HIP1R | -8467 |
| TF | -8494 |
| AVP | -8526 |
| SYS1 | -8533 |
| TUBB4B | -8578 |
| DENND2A | -8607 |
| ACTR10 | -8617 |
| ADRB2 | -8670 |
| GRK3 | -8680 |
| KIF21B | -8714 |
| NEDD8 | -8769 |
| ARPC2 | -8781 |
| RPS27A | -8850 |
| GABARAP | -8884 |
| TUBAL3 | -8959 |
| CNIH3 | -9039 |
| BET1L | -9131 |
| TRAPPC6A | -9153 |
| SYT2 | -9174 |
| FOLR1 | -9179 |
| SPTBN2 | -9204 |
| FTH1 | -9258 |
| CLTCL1 | -9266 |
| M6PR | -9267 |
| RAB8A | -9332 |
| STON2 | -9348 |
| KIF5A | -9351 |
| FNBP1L | -9384 |
| RAB36 | -9417 |
| RAB31 | -9434 |
| TRIP11 | -9507 |
| NAA30 | -9517 |
| KIF20A | -9622 |
| TUBA4A | -9708 |
| GGA3 | -9778 |
| TRAPPC3 | -9832 |
| ARF1 | -9843 |
| GRB2 | -9911 |
| ACTG1 | -9912 |
| CTSC | -10009 |
| ACTB | -10011 |
| GJD3 | -10023 |
| STX10 | -10074 |
| ARPC4 | -10108 |
| ARRB1 | -10145 |
| KIF3C | -10150 |
| AP2S1 | -10172 |
| TGOLN2 | -10240 |
| YWHAH | -10317 |
| BLOC1S3 | -10522 |
| CTSZ | -10581 |
| CAPZA1 | -10609 |
| AP1M2 | -10623 |
| CD3G | -10696 |
| AGTR1 | -10728 |
| APOB | -10737 |
| HBEGF | -10825 |
| GRIA1 | -10851 |
| MAN1A1 | -10891 |
| CHML | -10910 |
| RIN2 | -10971 |
| DENND2D | -10973 |
| ARF6 | -11165 |
| RAB6B | -11167 |
| GRK2 | -11277 |
| RAB39A | -11326 |
| CAPZA3 | -11545 |
| TBC1D10C | -11920 |
| CD3D | -12029 |
| FTL | -12213 |
| AREG | -12274 |
REACTOME_AMYLOID_FIBER_FORMATION
| 1623 | |
|---|---|
| set | REACTOME_AMYLOID_FIBER_FORMATION |
| setSize | 102 |
| pANOVA | 0.0124 |
| s.dist | -0.143 |
| p.adjustANOVA | 0.598 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| FGA | -12036.0 |
| IAPP | -11766.0 |
| H2BC14 | -11709.0 |
| SEMG1 | -11655.0 |
| H4C8 | -11506.0 |
| H2AC14 | -11332.0 |
| H4C1 | -11106.0 |
| LYZ | -11088.0 |
| LTF | -11083.0 |
| H2AC7 | -11040.5 |
| H2BC7 | -11040.5 |
| H3C1 | -10687.0 |
| BACE1 | -10554.0 |
| H3C12 | -10530.0 |
| H3C4 | -10465.0 |
| CALCA | -10279.0 |
| H4C6 | -10210.0 |
| GSN | -10042.0 |
| NAT8 | -9922.0 |
| GGA3 | -9778.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| FGA | -12036.0 |
| IAPP | -11766.0 |
| H2BC14 | -11709.0 |
| SEMG1 | -11655.0 |
| H4C8 | -11506.0 |
| H2AC14 | -11332.0 |
| H4C1 | -11106.0 |
| LYZ | -11088.0 |
| LTF | -11083.0 |
| H2AC7 | -11040.5 |
| H2BC7 | -11040.5 |
| H3C1 | -10687.0 |
| BACE1 | -10554.0 |
| H3C12 | -10530.0 |
| H3C4 | -10465.0 |
| CALCA | -10279.0 |
| H4C6 | -10210.0 |
| GSN | -10042.0 |
| NAT8 | -9922.0 |
| GGA3 | -9778.0 |
| H2BC11 | -9747.0 |
| H2BC6 | -9394.0 |
| B2M | -9168.0 |
| RPS27A | -8850.0 |
| APP | -8452.0 |
| H3-3B | -7678.0 |
| APCS | -7649.0 |
| UBC | -7516.0 |
| TSPAN15 | -7174.0 |
| SIAH2 | -7035.0 |
| H2BC1 | -7004.0 |
| TTR | -6894.0 |
| TSPAN14 | -6882.0 |
| H2BC5 | -6716.0 |
| SAA1 | -6701.0 |
| UBB | -6558.0 |
| GGA1 | -6121.0 |
| H2BC3 | -5808.0 |
| APOA1 | -5630.0 |
| H2BC26 | -5603.0 |
| H4C5 | -5492.0 |
| GGA2 | -5339.0 |
| H2BC4 | -5269.0 |
| MFGE8 | -5017.0 |
| HSPG2 | -4680.0 |
| H2AC20 | -4507.0 |
| H2BC17 | -4265.0 |
| ADAM10 | -4196.0 |
| SORL1 | -4192.0 |
| ITM2B | -4044.0 |
| PSENEN | -3417.0 |
| H2AZ1 | -3348.0 |
| TSPAN33 | -3025.0 |
| APOE | -2860.0 |
| H4C9 | -2491.0 |
| H4C2 | -2471.0 |
| NCSTN | -2455.0 |
| H3C6 | -2432.0 |
| H2BC21 | -2245.0 |
| H2AC8 | -1791.0 |
| SIAH1 | -1475.0 |
| H3-3A | -1455.0 |
| PRKN | -1336.0 |
| H3C2 | -1304.0 |
| SNCAIP | -1288.0 |
| H2AC6 | -1218.0 |
| H3C11 | -834.0 |
| H2BC13 | -344.0 |
| H3C8 | -157.0 |
| APH1B | 45.0 |
| ODAM | 73.0 |
| TSPAN5 | 933.0 |
| H2BC10 | 1052.0 |
| H2AC18 | 1298.5 |
| H2AC19 | 1298.5 |
| SNCA | 1514.0 |
| H2BC8 | 1727.0 |
| INS | 1760.0 |
| H4C12 | 1999.0 |
| CST3 | 2013.0 |
| APH1A | 2359.0 |
| H2BC12 | 2936.0 |
| APOA4 | 3806.0 |
| UBA52 | 4371.0 |
| H2AC4 | 4441.0 |
| PRL | 4492.0 |
| H3C10 | 4749.0 |
| UBE2L6 | 5145.0 |
| H4C3 | 5331.0 |
| TGFBI | 5369.0 |
| H4C4 | 5517.0 |
| H4C16 | 6148.0 |
| H4C11 | 6170.0 |
| CALB1 | 6506.0 |
| H4C13 | 6594.0 |
| H2BC9 | 6991.5 |
| H3C7 | 6991.5 |
| H2AX | 7107.0 |
| FURIN | 7145.0 |
| H3C3 | 7600.0 |
| NPPA | 8804.0 |
| H2BC15 | 8813.0 |
REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION
| 64 | |
|---|---|
| set | REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION |
| setSize | 98 |
| pANOVA | 0.0125 |
| s.dist | -0.146 |
| p.adjustANOVA | 0.598 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| S100A8 | -12422 |
| PDIA3 | -12248 |
| S100A9 | -12138 |
| FGA | -12036 |
| FGG | -11862 |
| CALR | -11407 |
| PSMB7 | -11240 |
| HMGB1 | -11028 |
| SEC61B | -10682 |
| PSMD13 | -10647 |
| PSMC5 | -9926 |
| PSMB3 | -9639 |
| TAP1 | -9276 |
| B2M | -9168 |
| PSMC4 | -9044 |
| PSMB4 | -9031 |
| RPS27A | -8850 |
| CD36 | -8750 |
| PSME2 | -8655 |
| PSMC2 | -8605 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| S100A8 | -12422 |
| PDIA3 | -12248 |
| S100A9 | -12138 |
| FGA | -12036 |
| FGG | -11862 |
| CALR | -11407 |
| PSMB7 | -11240 |
| HMGB1 | -11028 |
| SEC61B | -10682 |
| PSMD13 | -10647 |
| PSMC5 | -9926 |
| PSMB3 | -9639 |
| TAP1 | -9276 |
| B2M | -9168 |
| PSMC4 | -9044 |
| PSMB4 | -9031 |
| RPS27A | -8850 |
| CD36 | -8750 |
| PSME2 | -8655 |
| PSMC2 | -8605 |
| PSMC3 | -8583 |
| PSMB8 | -8422 |
| SEC61G | -8395 |
| TLR6 | -7989 |
| PSMB1 | -7961 |
| PSMD11 | -7679 |
| PSMD12 | -7653 |
| UBC | -7516 |
| VAMP3 | -7218 |
| PSMA1 | -7186 |
| LNPEP | -6886 |
| CTSL | -6722 |
| SEC61A1 | -6708 |
| UBB | -6558 |
| PSMD4 | -6474 |
| STX4 | -6415 |
| PSMB5 | -6101 |
| PSMB9 | -5962 |
| PSMA7 | -5784 |
| PSMD3 | -5582 |
| HLA-G | -5489 |
| HLA-E | -5359 |
| PSMA4 | -5279 |
| PSMB11 | -5123 |
| FGB | -5103 |
| CTSV | -5082 |
| PSMA2 | -5037 |
| PSMB10 | -4396 |
| PSME4 | -4311 |
| PSMA6 | -4225 |
| TLR4 | -3591 |
| MRC2 | -3296 |
| SEC22B | -3271 |
| MYD88 | -3176 |
| PSMD8 | -3004 |
| PSMD9 | -2679 |
| ITGB5 | -2660 |
| CYBA | -2406 |
| PSMD1 | -2198 |
| S100A1 | -2145 |
| NCF2 | -1640 |
| HLA-B | -1486 |
| NCF4 | -1029 |
| PSMD14 | -968 |
| PSMD5 | 47 |
| VAMP8 | 328 |
| HLA-F | 595 |
| PSMA3 | 761 |
| TAPBP | 918 |
| PSMD6 | 1244 |
| TLR1 | 1380 |
| PSME3 | 1619 |
| HLA-A | 1643 |
| SEM1 | 1961 |
| HLA-C | 2005 |
| PSMB2 | 2057 |
| CTSS | 2170 |
| PSMA5 | 2542 |
| PSME1 | 2636 |
| PSMB6 | 2700 |
| ITGAV | 3093 |
| PSMD2 | 3383 |
| PSMC6 | 3448 |
| UBA52 | 4371 |
| PSMC1 | 5036 |
| CD14 | 5065 |
| SNAP23 | 5360 |
| PSMD7 | 5490 |
| TIRAP | 5595 |
| PSMF1 | 6349 |
| TAP2 | 6516 |
| TLR2 | 7026 |
| SEC61A2 | 7159 |
| IKBKB | 7889 |
| PSMA8 | 8189 |
| CD207 | 8400 |
| CHUK | 8602 |
| LY96 | 8637 |
REACTOME_REMOVAL_OF_AMINOTERMINAL_PROPEPTIDES_FROM_GAMMA_CARBOXYLATED_PROTEINS
| 161 | |
|---|---|
| set | REACTOME_REMOVAL_OF_AMINOTERMINAL_PROPEPTIDES_FROM_GAMMA_CARBOXYLATED_PROTEINS |
| setSize | 8 |
| pANOVA | 0.0127 |
| s.dist | 0.509 |
| p.adjustANOVA | 0.598 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| BGLAP | 7676 |
| FURIN | 7145 |
| PROC | 7012 |
| F10 | 6178 |
| PROZ | 5463 |
| PROS1 | 2314 |
| F7 | 1776 |
| F2 | -4275 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| BGLAP | 7676 |
| FURIN | 7145 |
| PROC | 7012 |
| F10 | 6178 |
| PROZ | 5463 |
| PROS1 | 2314 |
| F7 | 1776 |
| F2 | -4275 |
REACTOME_ERYTHROPOIETIN_ACTIVATES_PHOSPHOLIPASE_C_GAMMA_PLCG
| 1412 | |
|---|---|
| set | REACTOME_ERYTHROPOIETIN_ACTIVATES_PHOSPHOLIPASE_C_GAMMA_PLCG |
| setSize | 7 |
| pANOVA | 0.0127 |
| s.dist | 0.544 |
| p.adjustANOVA | 0.598 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| JAK2 | 8174 |
| EPO | 8170 |
| EPOR | 5686 |
| IRS2 | 4506 |
| PLCG2 | 3580 |
| LYN | 2809 |
| PLCG1 | -1095 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| JAK2 | 8174 |
| EPO | 8170 |
| EPOR | 5686 |
| IRS2 | 4506 |
| PLCG2 | 3580 |
| LYN | 2809 |
| PLCG1 | -1095 |
REACTOME_TRANSCRIPTIONAL_REGULATION_BY_VENTX
| 1236 | |
|---|---|
| set | REACTOME_TRANSCRIPTIONAL_REGULATION_BY_VENTX |
| setSize | 41 |
| pANOVA | 0.0137 |
| s.dist | 0.222 |
| p.adjustANOVA | 0.616 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| MIR24-1 | 9041 |
| RELA | 8703 |
| ANAPC1 | 8165 |
| ANAPC2 | 8132 |
| CDC23 | 7628 |
| EHMT1 | 7514 |
| EHMT2 | 7237 |
| MIR24-2 | 6760 |
| FZR1 | 6385 |
| ANAPC4 | 5471 |
| TNRC6A | 4958 |
| AGO3 | 4409 |
| TP53 | 4288 |
| ANAPC11 | 4125 |
| ANAPC10 | 3735 |
| CDC16 | 3502 |
| UBE2S | 3469 |
| IL6 | 3431 |
| CEBPB | 3224 |
| CTNNB1 | 2534 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MIR24-1 | 9041 |
| RELA | 8703 |
| ANAPC1 | 8165 |
| ANAPC2 | 8132 |
| CDC23 | 7628 |
| EHMT1 | 7514 |
| EHMT2 | 7237 |
| MIR24-2 | 6760 |
| FZR1 | 6385 |
| ANAPC4 | 5471 |
| TNRC6A | 4958 |
| AGO3 | 4409 |
| TP53 | 4288 |
| ANAPC11 | 4125 |
| ANAPC10 | 3735 |
| CDC16 | 3502 |
| UBE2S | 3469 |
| IL6 | 3431 |
| CEBPB | 3224 |
| CTNNB1 | 2534 |
| UBE2D1 | 2345 |
| MOV10 | 2211 |
| TCF7L2 | 2208 |
| TNRC6B | 1978 |
| CDC27 | 181 |
| LEF1 | -784 |
| CCND1 | -813 |
| CDC26 | -919 |
| UBE2E1 | -2139 |
| ANAPC7 | -2456 |
| ANAPC5 | -4131 |
| AGO4 | -4233 |
| CSF1R | -4341 |
| TNRC6C | -4434 |
| CDKN2A | -5373 |
| ANAPC15 | -5689 |
| NFKB1 | -5696 |
| UBE2C | -6545 |
| ANAPC16 | -10301 |
| VENTX | -10652 |
| AGO1 | -11740 |
REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION_OF_SATURATED_FATTY_ACIDS
| 1199 | |
|---|---|
| set | REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION_OF_SATURATED_FATTY_ACIDS |
| setSize | 11 |
| pANOVA | 0.0139 |
| s.dist | 0.428 |
| p.adjustANOVA | 0.616 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| ACADS | 9127 |
| ACADL | 8784 |
| ACSM3 | 8177 |
| ECHS1 | 8017 |
| HADH | 5335 |
| ACADVL | 3668 |
| HADHB | 3228 |
| MECR | 1572 |
| HADHA | -985 |
| ACADM | -2887 |
| ACSM6 | -7977 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ACADS | 9127 |
| ACADL | 8784 |
| ACSM3 | 8177 |
| ECHS1 | 8017 |
| HADH | 5335 |
| ACADVL | 3668 |
| HADHB | 3228 |
| MECR | 1572 |
| HADHA | -985 |
| ACADM | -2887 |
| ACSM6 | -7977 |
REACTOME_TRANSLATION
| 1152 | |
|---|---|
| set | REACTOME_TRANSLATION |
| setSize | 278 |
| pANOVA | 0.0151 |
| s.dist | -0.0847 |
| p.adjustANOVA | 0.623 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL35A | -11731 |
| RPL12 | -11317 |
| TRAM1 | -11310 |
| SRP9 | -11211 |
| RPL10A | -10960 |
| MRPL3 | -10701 |
| SEC61B | -10682 |
| RPL23A | -10666 |
| MRPL58 | -10645 |
| RPS13 | -10627 |
| EEF1G | -10610 |
| LARS1 | -10567 |
| RPL18 | -10404 |
| TUFM | -10286 |
| DARS2 | -10249 |
| RPL35 | -10232 |
| MTRF1L | -10118 |
| MRPL53 | -10081 |
| EIF2S1 | -9753 |
| RPL8 | -9570 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL35A | -11731.0 |
| RPL12 | -11317.0 |
| TRAM1 | -11310.0 |
| SRP9 | -11211.0 |
| RPL10A | -10960.0 |
| MRPL3 | -10701.0 |
| SEC61B | -10682.0 |
| RPL23A | -10666.0 |
| MRPL58 | -10645.0 |
| RPS13 | -10627.0 |
| EEF1G | -10610.0 |
| LARS1 | -10567.0 |
| RPL18 | -10404.0 |
| TUFM | -10286.0 |
| DARS2 | -10249.0 |
| RPL35 | -10232.0 |
| MTRF1L | -10118.0 |
| MRPL53 | -10081.0 |
| EIF2S1 | -9753.0 |
| RPL8 | -9570.0 |
| RPL30 | -9564.0 |
| MARS2 | -9554.0 |
| RPS8 | -9372.0 |
| MRPS7 | -9302.0 |
| SRP72 | -9247.0 |
| RPS23 | -9186.0 |
| RPL3 | -9036.0 |
| RPL37 | -9016.0 |
| MRPL55 | -9006.0 |
| RPLP2 | -8901.0 |
| RPS27A | -8850.0 |
| EEF1B2 | -8847.0 |
| MRPS15 | -8812.0 |
| EEF1A1 | -8773.0 |
| SPCS1 | -8736.0 |
| MRPL24 | -8663.0 |
| EIF4E | -8547.0 |
| MRPS18A | -8522.0 |
| MRPL48 | -8512.0 |
| MRPL27 | -8495.0 |
| MRPS34 | -8433.0 |
| SEC61G | -8395.0 |
| EIF3J | -8370.0 |
| RPL36 | -8324.0 |
| MRPS16 | -8295.0 |
| MRPL40 | -8280.0 |
| EIF3I | -8146.0 |
| RPS10 | -8127.0 |
| RPN1 | -8112.0 |
| MRPL41 | -8085.0 |
| MRPS24 | -8077.0 |
| PTCD3 | -8068.0 |
| CHCHD1 | -8039.0 |
| MRPS23 | -7950.0 |
| RPS15A | -7940.0 |
| AURKAIP1 | -7917.0 |
| RPS18 | -7899.0 |
| RPS6 | -7875.0 |
| SSR1 | -7720.0 |
| EIF4A1 | -7666.0 |
| EIF3H | -7584.0 |
| RPL27A | -7502.0 |
| EIF2B1 | -7432.0 |
| RPL7 | -7346.0 |
| MRPL14 | -7316.0 |
| MRPL52 | -7290.0 |
| EIF5B | -7264.0 |
| MRPL2 | -7242.0 |
| RPS25 | -7128.0 |
| MRPL44 | -7118.0 |
| RPL41 | -7109.0 |
| TSFM | -7100.0 |
| EIF3F | -7042.0 |
| YARS2 | -6933.0 |
| RPL15 | -6931.0 |
| MRPL47 | -6865.0 |
| MRPS22 | -6847.0 |
| MRPL38 | -6843.0 |
| MRPS26 | -6772.0 |
| MRPL4 | -6745.0 |
| SEC61A1 | -6708.0 |
| RPS2 | -6644.0 |
| RPS14 | -6614.0 |
| SEC11A | -6485.0 |
| RPL17 | -6404.0 |
| RPS27 | -6385.0 |
| HARS1 | -6368.0 |
| RPL38 | -6209.0 |
| RPS7 | -6174.0 |
| TRMT112 | -6119.0 |
| EEF1A2 | -5960.0 |
| RPL28 | -5935.0 |
| MRPL13 | -5925.0 |
| EIF3K | -5828.0 |
| RPLP0 | -5821.0 |
| EIF4H | -5786.0 |
| RPS24 | -5735.0 |
| MRPL33 | -5545.0 |
| RPL13 | -5315.0 |
| MRPL32 | -5297.0 |
| FARSA | -5127.0 |
| RPL21 | -5078.0 |
| MRPL11 | -5065.0 |
| SRP54 | -5063.0 |
| ERAL1 | -4951.0 |
| RPS3 | -4929.0 |
| CARS1 | -4919.0 |
| EIF4A2 | -4628.0 |
| MRPL21 | -4606.0 |
| RPL11 | -4567.0 |
| MRPS12 | -4498.0 |
| RPS26 | -4458.0 |
| SSR2 | -4404.0 |
| GSPT1 | -4335.0 |
| RPL9 | -4316.0 |
| RPLP1 | -4306.0 |
| OXA1L | -4254.0 |
| MRPL12 | -4230.0 |
| YARS1 | -4150.0 |
| FAU | -4024.0 |
| MRPL16 | -3902.0 |
| SPCS2 | -3893.0 |
| RPS11 | -3891.0 |
| RPL39L | -3705.0 |
| MRPS21 | -3673.0 |
| RPL18A | -3568.0 |
| HARS2 | -3486.0 |
| MRPS9 | -3225.0 |
| RPL31 | -3185.0 |
| PPA2 | -3143.0 |
| MRPL17 | -3138.0 |
| RPL36AL | -3061.5 |
| SARS2 | -3051.0 |
| RPL6 | -3002.0 |
| SRP14 | -2981.0 |
| MRPL57 | -2975.0 |
| MRPL34 | -2937.0 |
| MRPL19 | -2921.0 |
| MRPS11 | -2892.0 |
| SPCS3 | -2825.0 |
| NARS1 | -2590.0 |
| MRPL49 | -2510.0 |
| GFM2 | -2503.0 |
| MARS1 | -2394.0 |
| ETF1 | -2365.0 |
| MRPL35 | -2357.0 |
| MTFMT | -2302.0 |
| DDOST | -2258.0 |
| RPL5 | -2041.0 |
| KARS1 | -2017.0 |
| RPL29 | -2004.0 |
| MRPS2 | -2000.0 |
| EIF2B4 | -1981.0 |
| LARS2 | -1936.0 |
| FARSB | -1855.0 |
| RPL13A | -1763.5 |
| SEC11C | -1576.0 |
| RPL14 | -1458.0 |
| EIF4B | -1368.0 |
| RPS29 | -1284.0 |
| MRPL50 | -1078.0 |
| RPL37A | -1041.0 |
| RPL22L1 | -925.0 |
| RPL7A | -848.0 |
| RPS28 | -820.0 |
| MRPL43 | -739.0 |
| MRPS18C | -725.0 |
| MRPL18 | -660.0 |
| EIF3G | -643.0 |
| MRPS25 | -610.0 |
| RPS19 | -560.0 |
| EIF4EBP1 | -463.0 |
| MRPL46 | -444.0 |
| EIF3D | -399.0 |
| MRPL36 | -382.0 |
| MRPL37 | -363.0 |
| MRPL20 | -352.0 |
| RPL19 | -351.0 |
| NARS2 | -327.0 |
| MRPL22 | -257.0 |
| PABPC1 | -207.0 |
| RPS5 | -141.0 |
| RARS2 | -65.0 |
| MRRF | -59.0 |
| AARS2 | -9.0 |
| MRPS6 | 256.0 |
| DARS1 | 275.0 |
| MRPS30 | 336.0 |
| MRPL15 | 417.0 |
| RPS21 | 432.0 |
| RPS27L | 478.0 |
| RPS16 | 492.0 |
| CARS2 | 559.0 |
| MRPL42 | 652.0 |
| RPL32 | 844.0 |
| MRPL10 | 1012.0 |
| RPL26L1 | 1044.0 |
| MRPS5 | 1225.0 |
| RPN2 | 1322.0 |
| SRP19 | 1413.0 |
| SRPRA | 1427.0 |
| RARS1 | 1441.0 |
| RPS12 | 1537.0 |
| GFM1 | 1689.0 |
| EIF3E | 1729.0 |
| RPSA | 1951.0 |
| EIF5 | 1984.0 |
| EIF2B2 | 2049.0 |
| MRPS35 | 2228.0 |
| MRPL54 | 2268.0 |
| MRPS27 | 2334.0 |
| IARS2 | 2394.0 |
| SRPRB | 2418.0 |
| RPS9 | 2453.0 |
| MRPS33 | 2671.0 |
| MRPL30 | 2689.0 |
| SRP68 | 2954.0 |
| WARS1 | 3087.0 |
| SSR3 | 3114.0 |
| EPRS1 | 3276.0 |
| RPS20 | 3296.0 |
| PPA1 | 3361.0 |
| EIF4G1 | 3425.0 |
| RPS15 | 3520.0 |
| RPL24 | 3534.0 |
| EEF1D | 3594.0 |
| RPS3A | 3653.0 |
| IARS1 | 3878.0 |
| PARS2 | 3902.0 |
| EIF3A | 3917.0 |
| MRPL1 | 3945.0 |
| MRPL51 | 4107.0 |
| RPL23 | 4201.0 |
| EARS2 | 4209.0 |
| MRPS18B | 4324.0 |
| VARS1 | 4354.0 |
| UBA52 | 4371.0 |
| MRPL39 | 4391.0 |
| RPL34 | 4400.0 |
| FARS2 | 4519.0 |
| EIF3M | 4583.0 |
| MTIF2 | 4655.0 |
| MRPL23 | 4736.0 |
| MRPL28 | 4803.0 |
| TARS1 | 4867.0 |
| EIF2S2 | 4898.0 |
| MRPS31 | 4965.0 |
| DAP3 | 4967.0 |
| EEF1E1 | 5075.0 |
| EIF2B3 | 5130.0 |
| RPL4 | 5158.0 |
| MRPS28 | 5372.0 |
| GARS1 | 5580.0 |
| MTIF3 | 5631.0 |
| AARS1 | 5705.0 |
| WARS2 | 5744.0 |
| APEH | 5853.0 |
| MRPL9 | 5897.0 |
| GADD45GIP1 | 5933.0 |
| EIF3L | 6155.0 |
| EIF3B | 6235.0 |
| EEF2 | 6286.0 |
| VARS2 | 6463.0 |
| AIMP2 | 6482.0 |
| RPL10L | 6655.0 |
| TARS2 | 6813.0 |
| N6AMT1 | 7002.0 |
| AIMP1 | 7146.0 |
| RPL27 | 7151.0 |
| SEC61A2 | 7159.0 |
| MRPS14 | 7496.0 |
| EIF2B5 | 7499.0 |
| MRPL45 | 7611.0 |
| RPL26 | 7721.0 |
| MRPS17 | 7780.0 |
| RPL22 | 7815.0 |
| MRPS10 | 8678.0 |
| RPL3L | 9151.0 |
REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK
| 618 | |
|---|---|
| set | REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK |
| setSize | 28 |
| pANOVA | 0.0156 |
| s.dist | 0.264 |
| p.adjustANOVA | 0.623 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TSC2 | 8343 |
| PRKAA2 | 7672 |
| RPTOR | 6730 |
| STK11 | 6647 |
| MTOR | 6285 |
| PRKAG3 | 6061 |
| CAB39 | 5988 |
| PRKAB1 | 5077 |
| LAMTOR3 | 4577 |
| TSC1 | 3972 |
| PRKAG2 | 3279 |
| LAMTOR4 | 2978 |
| SLC38A9 | 2917 |
| PRKAA1 | 1528 |
| LAMTOR5 | 1049 |
| RRAGA | 333 |
| LAMTOR1 | 215 |
| RHEB | -181 |
| PRKAG1 | -424 |
| LAMTOR2 | -845 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TSC2 | 8343 |
| PRKAA2 | 7672 |
| RPTOR | 6730 |
| STK11 | 6647 |
| MTOR | 6285 |
| PRKAG3 | 6061 |
| CAB39 | 5988 |
| PRKAB1 | 5077 |
| LAMTOR3 | 4577 |
| TSC1 | 3972 |
| PRKAG2 | 3279 |
| LAMTOR4 | 2978 |
| SLC38A9 | 2917 |
| PRKAA1 | 1528 |
| LAMTOR5 | 1049 |
| RRAGA | 333 |
| LAMTOR1 | 215 |
| RHEB | -181 |
| PRKAG1 | -424 |
| LAMTOR2 | -845 |
| MLST8 | -872 |
| STRADB | -1082 |
| CAB39L | -1091 |
| STRADA | -2628 |
| PPM1A | -5403 |
| PRKAB2 | -5450 |
| RRAGD | -7024 |
| RRAGC | -7535 |
REACTOME_ERYTHROPOIETIN_ACTIVATES_STAT5
| 1413 | |
|---|---|
| set | REACTOME_ERYTHROPOIETIN_ACTIVATES_STAT5 |
| setSize | 7 |
| pANOVA | 0.0157 |
| s.dist | 0.527 |
| p.adjustANOVA | 0.623 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| JAK2 | 8174 |
| EPO | 8170 |
| EPOR | 5686 |
| IRS2 | 4506 |
| LYN | 2809 |
| STAT5B | 2568 |
| STAT5A | -1363 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| JAK2 | 8174 |
| EPO | 8170 |
| EPOR | 5686 |
| IRS2 | 4506 |
| LYN | 2809 |
| STAT5B | 2568 |
| STAT5A | -1363 |
REACTOME_TYROSINE_CATABOLISM
| 1321 | |
|---|---|
| set | REACTOME_TYROSINE_CATABOLISM |
| setSize | 5 |
| pANOVA | 0.0159 |
| s.dist | -0.623 |
| p.adjustANOVA | 0.623 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| HPD | -11448 |
| HGD | -11429 |
| TAT | -10336 |
| FAH | -5376 |
| GSTZ1 | -2838 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| HPD | -11448 |
| HGD | -11429 |
| TAT | -10336 |
| FAH | -5376 |
| GSTZ1 | -2838 |
REACTOME_EUKARYOTIC_TRANSLATION_INITIATION
| 1149 | |
|---|---|
| set | REACTOME_EUKARYOTIC_TRANSLATION_INITIATION |
| setSize | 110 |
| pANOVA | 0.0159 |
| s.dist | -0.133 |
| p.adjustANOVA | 0.623 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL35A | -11731 |
| RPL12 | -11317 |
| RPL10A | -10960 |
| RPL23A | -10666 |
| RPS13 | -10627 |
| RPL18 | -10404 |
| RPL35 | -10232 |
| EIF2S1 | -9753 |
| RPL8 | -9570 |
| RPL30 | -9564 |
| RPS8 | -9372 |
| RPS23 | -9186 |
| RPL3 | -9036 |
| RPL37 | -9016 |
| RPLP2 | -8901 |
| RPS27A | -8850 |
| EIF4E | -8547 |
| EIF3J | -8370 |
| RPL36 | -8324 |
| EIF3I | -8146 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL35A | -11731.0 |
| RPL12 | -11317.0 |
| RPL10A | -10960.0 |
| RPL23A | -10666.0 |
| RPS13 | -10627.0 |
| RPL18 | -10404.0 |
| RPL35 | -10232.0 |
| EIF2S1 | -9753.0 |
| RPL8 | -9570.0 |
| RPL30 | -9564.0 |
| RPS8 | -9372.0 |
| RPS23 | -9186.0 |
| RPL3 | -9036.0 |
| RPL37 | -9016.0 |
| RPLP2 | -8901.0 |
| RPS27A | -8850.0 |
| EIF4E | -8547.0 |
| EIF3J | -8370.0 |
| RPL36 | -8324.0 |
| EIF3I | -8146.0 |
| RPS10 | -8127.0 |
| RPS15A | -7940.0 |
| RPS18 | -7899.0 |
| RPS6 | -7875.0 |
| EIF4A1 | -7666.0 |
| EIF3H | -7584.0 |
| RPL27A | -7502.0 |
| EIF2B1 | -7432.0 |
| RPL7 | -7346.0 |
| EIF5B | -7264.0 |
| RPS25 | -7128.0 |
| RPL41 | -7109.0 |
| EIF3F | -7042.0 |
| RPL15 | -6931.0 |
| RPS2 | -6644.0 |
| RPS14 | -6614.0 |
| RPL17 | -6404.0 |
| RPS27 | -6385.0 |
| RPL38 | -6209.0 |
| RPS7 | -6174.0 |
| RPL28 | -5935.0 |
| EIF3K | -5828.0 |
| RPLP0 | -5821.0 |
| EIF4H | -5786.0 |
| RPS24 | -5735.0 |
| RPL13 | -5315.0 |
| RPL21 | -5078.0 |
| RPS3 | -4929.0 |
| EIF4A2 | -4628.0 |
| RPL11 | -4567.0 |
| RPS26 | -4458.0 |
| RPL9 | -4316.0 |
| RPLP1 | -4306.0 |
| FAU | -4024.0 |
| RPS11 | -3891.0 |
| RPL39L | -3705.0 |
| RPL18A | -3568.0 |
| RPL31 | -3185.0 |
| RPL36AL | -3061.5 |
| RPL6 | -3002.0 |
| RPL5 | -2041.0 |
| RPL29 | -2004.0 |
| EIF2B4 | -1981.0 |
| RPL13A | -1763.5 |
| RPL14 | -1458.0 |
| EIF4B | -1368.0 |
| RPS29 | -1284.0 |
| RPL37A | -1041.0 |
| RPL22L1 | -925.0 |
| RPL7A | -848.0 |
| RPS28 | -820.0 |
| EIF3G | -643.0 |
| RPS19 | -560.0 |
| EIF4EBP1 | -463.0 |
| EIF3D | -399.0 |
| RPL19 | -351.0 |
| PABPC1 | -207.0 |
| RPS5 | -141.0 |
| RPS21 | 432.0 |
| RPS27L | 478.0 |
| RPS16 | 492.0 |
| RPL32 | 844.0 |
| RPL26L1 | 1044.0 |
| RPS12 | 1537.0 |
| EIF3E | 1729.0 |
| RPSA | 1951.0 |
| EIF5 | 1984.0 |
| EIF2B2 | 2049.0 |
| RPS9 | 2453.0 |
| RPS20 | 3296.0 |
| EIF4G1 | 3425.0 |
| RPS15 | 3520.0 |
| RPL24 | 3534.0 |
| RPS3A | 3653.0 |
| EIF3A | 3917.0 |
| RPL23 | 4201.0 |
| UBA52 | 4371.0 |
| RPL34 | 4400.0 |
| EIF3M | 4583.0 |
| EIF2S2 | 4898.0 |
| EIF2B3 | 5130.0 |
| RPL4 | 5158.0 |
| EIF3L | 6155.0 |
| EIF3B | 6235.0 |
| RPL10L | 6655.0 |
| RPL27 | 7151.0 |
| EIF2B5 | 7499.0 |
| RPL26 | 7721.0 |
| RPL22 | 7815.0 |
| RPL3L | 9151.0 |
REACTOME_INTERFERON_ALPHA_BETA_SIGNALING
| 1432 | |
|---|---|
| set | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING |
| setSize | 70 |
| pANOVA | 0.0172 |
| s.dist | 0.165 |
| p.adjustANOVA | 0.657 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| IFNA21 | 9565 |
| IFITM2 | 9267 |
| XAF1 | 9029 |
| IFNB1 | 8825 |
| IFNA16 | 8795 |
| ISG15 | 8677 |
| OAS1 | 8534 |
| TYK2 | 8411 |
| IFNA6 | 8378 |
| IFIT2 | 8295 |
| OAS2 | 8069 |
| STAT2 | 8033 |
| RNASEL | 7709 |
| IFITM1 | 7284 |
| KPNA1 | 7173 |
| ADAR | 6783 |
| IFNA14 | 5600 |
| ABCE1 | 4678 |
| IRF9 | 4196 |
| STAT1 | 4195 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| IFNA21 | 9565 |
| IFITM2 | 9267 |
| XAF1 | 9029 |
| IFNB1 | 8825 |
| IFNA16 | 8795 |
| ISG15 | 8677 |
| OAS1 | 8534 |
| TYK2 | 8411 |
| IFNA6 | 8378 |
| IFIT2 | 8295 |
| OAS2 | 8069 |
| STAT2 | 8033 |
| RNASEL | 7709 |
| IFITM1 | 7284 |
| KPNA1 | 7173 |
| ADAR | 6783 |
| IFNA14 | 5600 |
| ABCE1 | 4678 |
| IRF9 | 4196 |
| STAT1 | 4195 |
| IP6K2 | 4032 |
| IFIT1 | 3909 |
| IRF5 | 3720 |
| JAK1 | 2931 |
| USP18 | 2727 |
| IFIT3 | 2434 |
| PTPN11 | 2193 |
| HLA-C | 2005 |
| IFNA13 | 1939 |
| MX1 | 1827 |
| GBP2 | 1820 |
| HLA-A | 1643 |
| MX2 | 1534 |
| IRF3 | 1158 |
| ISG20 | 871 |
| IFI35 | 858 |
| HLA-F | 595 |
| IRF2 | 208 |
| IFI6 | 52 |
| PTPN1 | -211 |
| IFIT5 | -666 |
| BST2 | -1266 |
| HLA-B | -1486 |
| KPNB1 | -1727 |
| IRF7 | -1773 |
| HLA-H | -2325 |
| IFNAR1 | -2349 |
| OAS3 | -2446 |
| IFNAR2 | -3542 |
| IFNA2 | -3772 |
| EGR1 | -4536 |
| IRF6 | -4850 |
| HLA-E | -5359 |
| HLA-G | -5489 |
| IRF4 | -5616 |
| IFI27 | -5995 |
| IRF1 | -6187 |
| PTPN6 | -6254 |
| IFNA8 | -6348 |
| RSAD2 | -6477 |
| OASL | -6549 |
| SOCS3 | -6561 |
| IFNA5 | -6575 |
| IFITM3 | -7070 |
| SAMHD1 | -7663 |
| IRF8 | -7815 |
| PSMB8 | -8422 |
| IFNA1 | -9959 |
| IFNA7 | -10849 |
| SOCS1 | -11700 |
REACTOME_HEME_SIGNALING
| 1579 | |
|---|---|
| set | REACTOME_HEME_SIGNALING |
| setSize | 47 |
| pANOVA | 0.0191 |
| s.dist | 0.198 |
| p.adjustANOVA | 0.7 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| LY96 | 8637 |
| CREB1 | 7072 |
| SIRT1 | 6379 |
| NCOA1 | 5925 |
| ATF2 | 5884 |
| HMOX1 | 5812 |
| NRIP1 | 5594 |
| CARM1 | 5520 |
| BMAL1 | 4992 |
| CRTC1 | 4918 |
| TBL1XR1 | 4893 |
| PPARGC1A | 4753 |
| HELZ2 | 4690 |
| RAI1 | 4511 |
| HBB | 4410 |
| RORA | 4281 |
| EP300 | 3970 |
| HDAC3 | 3966 |
| MAFK | 3807 |
| MEF2C | 3665 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| LY96 | 8637 |
| CREB1 | 7072 |
| SIRT1 | 6379 |
| NCOA1 | 5925 |
| ATF2 | 5884 |
| HMOX1 | 5812 |
| NRIP1 | 5594 |
| CARM1 | 5520 |
| BMAL1 | 4992 |
| CRTC1 | 4918 |
| TBL1XR1 | 4893 |
| PPARGC1A | 4753 |
| HELZ2 | 4690 |
| RAI1 | 4511 |
| HBB | 4410 |
| RORA | 4281 |
| EP300 | 3970 |
| HDAC3 | 3966 |
| MAFK | 3807 |
| MEF2C | 3665 |
| CRTC3 | 2245 |
| HBA2 | 2106 |
| NCOR1 | 2075 |
| USP46 | 1932 |
| CREBBP | 1880 |
| NR1D1 | 1555 |
| NCOA2 | 1391 |
| CRTC2 | 1338 |
| NPAS2 | 839 |
| PPARA | 540 |
| SLC46A1 | 441 |
| NCOA6 | 434 |
| BACH1 | 83 |
| MED1 | -765 |
| RXRA | -1749 |
| NFE2L2 | -1913 |
| TGS1 | -2388 |
| CLOCK | -3538 |
| TLR4 | -3591 |
| CHD9 | -5476 |
| APOA1 | -5630 |
| SMARCD3 | -8832 |
| HBA1 | -9603 |
| CLEC1B | -10291 |
| XPO1 | -10380 |
| APOB | -10737 |
| MEF2D | -11073 |
REACTOME_CILIUM_ASSEMBLY
| 902 | |
|---|---|
| set | REACTOME_CILIUM_ASSEMBLY |
| setSize | 190 |
| pANOVA | 0.0197 |
| s.dist | 0.0981 |
| p.adjustANOVA | 0.7 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TUBA3E | 9124 |
| PKD1 | 8488 |
| SSNA1 | 8248 |
| CEP152 | 8204 |
| DYNC2I1 | 8006 |
| CEP131 | 7891 |
| TCTN2 | 7870 |
| HAUS4 | 7799 |
| IFT52 | 7796 |
| TUBA3C | 7743 |
| KIF24 | 7723 |
| SSTR3 | 7634 |
| CEP72 | 7114 |
| CCT2 | 7076 |
| NPHP4 | 7033 |
| PCNT | 6774 |
| IFT43 | 6673 |
| DYNC1H1 | 6590 |
| TUBB1 | 6551 |
| DYNLT2B | 6543 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TUBA3E | 9124 |
| PKD1 | 8488 |
| SSNA1 | 8248 |
| CEP152 | 8204 |
| DYNC2I1 | 8006 |
| CEP131 | 7891 |
| TCTN2 | 7870 |
| HAUS4 | 7799 |
| IFT52 | 7796 |
| TUBA3C | 7743 |
| KIF24 | 7723 |
| SSTR3 | 7634 |
| CEP72 | 7114 |
| CCT2 | 7076 |
| NPHP4 | 7033 |
| PCNT | 6774 |
| IFT43 | 6673 |
| DYNC1H1 | 6590 |
| TUBB1 | 6551 |
| DYNLT2B | 6543 |
| DCTN1 | 6373 |
| HAUS1 | 6098 |
| DCTN3 | 5936 |
| IFT74 | 5791 |
| EXOC3 | 5616 |
| EXOC2 | 5545 |
| CDK5RAP2 | 5478 |
| EXOC5 | 5383 |
| MARK4 | 5359 |
| PRKAR2B | 5355 |
| CEP164 | 5227 |
| TUBB2B | 5220 |
| AKAP9 | 5212 |
| SFI1 | 5204 |
| INPP5E | 5029 |
| TTBK2 | 5009 |
| IFT80 | 4807 |
| AHI1 | 4722 |
| CEP83 | 4703 |
| BBS7 | 4691 |
| DYNC2I2 | 4676 |
| CEP57 | 4653 |
| PAFAH1B1 | 4510 |
| UNC119B | 4417 |
| BBIP1 | 4333 |
| CEP97 | 4282 |
| TCP1 | 4160 |
| ACTR1A | 4136 |
| IFT140 | 4042 |
| HAUS5 | 3986 |
| PKD2 | 3949 |
| RAB3IP | 3640 |
| RAB11FIP3 | 3610 |
| B9D1 | 3480 |
| TMEM67 | 3330 |
| TUBB8 | 3302 |
| KIF3B | 3092 |
| ARL13B | 2992 |
| IFT88 | 2930 |
| NPHP1 | 2910 |
| EXOC7 | 2820 |
| PLK4 | 2676 |
| NEDD1 | 2492 |
| CEP250 | 2463 |
| CEP41 | 2460 |
| KIFAP3 | 2431 |
| NDE1 | 2400 |
| DYNC2H1 | 2385 |
| CEP192 | 2152 |
| EXOC4 | 2122 |
| TUBA3D | 2121 |
| IFT22 | 2062 |
| CKAP5 | 2046 |
| CCT3 | 1962 |
| BBS2 | 1931 |
| IFT172 | 1811 |
| CEP162 | 1647 |
| RAB11A | 1467 |
| TCTN3 | 1401 |
| TCTN1 | 1269 |
| CEP290 | 1033 |
| NPHP3 | 998 |
| TUBB4A | 911 |
| EXOC1 | 849 |
| ARL6 | 827 |
| CC2D2A | 638 |
| FBF1 | 587 |
| CLASP1 | 573 |
| ALMS1 | 502 |
| CNGB1 | 445 |
| CNGA4 | 439 |
| ODF2 | 358 |
| IFT81 | 283 |
| CEP89 | 228 |
| IFT122 | 198 |
| DCTN2 | 111 |
| TUBB6 | 10 |
| BBS4 | -95 |
| CENPJ | -126 |
| CSNK1D | -196 |
| TUBA1A | -478 |
| SDCCAG8 | -548 |
| TUBA1C | -627 |
| TUBA8 | -738 |
| YWHAE | -881 |
| IFT57 | -914 |
| SMO | -957 |
| GBF1 | -995 |
| ARL3 | -1067 |
| TUBG1 | -1088 |
| HSP90AA1 | -1097 |
| TUBB3 | -1149 |
| CEP43 | -1173 |
| CEP135 | -1250 |
| RPGRIP1L | -1283 |
| DYNC1I2 | -1405 |
| DYNC2LI1 | -1426 |
| TNPO1 | -1502 |
| PCM1 | -1883 |
| MCHR1 | -1991 |
| CCT4 | -2144 |
| TTC21B | -2157 |
| BBS9 | -2224 |
| ATAT1 | -2248 |
| NEK2 | -2530 |
| MKKS | -2551 |
| TTC8 | -2607 |
| MAPRE1 | -2719 |
| DYNLT2 | -2731 |
| KIF3A | -2796 |
| HAUS8 | -3056 |
| CEP76 | -3207 |
| CEP70 | -3284 |
| BBS1 | -3367 |
| CCT8 | -3865 |
| EXOC6 | -3979 |
| TUBA4B | -4076 |
| KIF17 | -4087 |
| C2CD3 | -4235 |
| HAUS3 | -4258 |
| CEP63 | -4405 |
| TUBA1B | -4626 |
| BBS5 | -4691 |
| IFT46 | -4705 |
| BBS10 | -4974 |
| BBS12 | -5071 |
| WDR19 | -5209 |
| CDK1 | -5212 |
| PDE6D | -5429 |
| DYNLRB1 | -5464 |
| CYS1 | -5674 |
| CCP110 | -5698 |
| LZTFL1 | -5752 |
| CNTRL | -5979 |
| YWHAG | -6009 |
| DYNLL1 | -6011 |
| WDR35 | -6300 |
| SCLT1 | -6329 |
| ASAP1 | -6394 |
| ARF4 | -6448 |
| TRAF3IP1 | -6499 |
| EXOC8 | -6635 |
| CEP78 | -6803 |
| PLK1 | -6830 |
| PPP2R1A | -6897 |
| IQCB1 | -7166 |
| PRKACA | -7677 |
| IFT27 | -7741 |
| DYNLRB2 | -7748 |
| B9D2 | -7924 |
| DYNLL2 | -8069 |
| CSNK1E | -8153 |
| CCT5 | -8203 |
| TUBB2A | -8245 |
| TUBB4B | -8578 |
| CLUAP1 | -8636 |
| TUBB | -8667 |
| TUBAL3 | -8959 |
| TMEM216 | -9234 |
| RAB8A | -9332 |
| RHO | -9341 |
| DYNLT5 | -9498 |
| TRIP11 | -9507 |
| TUBA4A | -9708 |
| NINL | -10039 |
| HAUS2 | -10142 |
| KIF3C | -10150 |
| IFT20 | -10237 |
| MKS1 | -10808 |
| HAUS6 | -11336 |
REACTOME_MET_ACTIVATES_PI3K_AKT_SIGNALING
| 1231 | |
|---|---|
| set | REACTOME_MET_ACTIVATES_PI3K_AKT_SIGNALING |
| setSize | 6 |
| pANOVA | 0.0198 |
| s.dist | -0.549 |
| p.adjustANOVA | 0.7 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| GRB2 | -9911 |
| MET | -9188 |
| HGF | -7483 |
| GAB1 | -6306 |
| PIK3CA | -6283 |
| PIK3R1 | -5692 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| GRB2 | -9911 |
| MET | -9188 |
| HGF | -7483 |
| GAB1 | -6306 |
| PIK3CA | -6283 |
| PIK3R1 | -5692 |
REACTOME_ABC_TRANSPORTER_DISORDERS
| 903 | |
|---|---|
| set | REACTOME_ABC_TRANSPORTER_DISORDERS |
| setSize | 76 |
| pANOVA | 0.0202 |
| s.dist | -0.154 |
| p.adjustANOVA | 0.7 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| ABCB11 | -11664 |
| DERL3 | -11482 |
| PSMB7 | -11240 |
| ABCC6 | -10814 |
| PSMD13 | -10647 |
| DERL2 | -10476 |
| PSMC5 | -9926 |
| ABCC9 | -9773 |
| PSMB3 | -9639 |
| ABCC2 | -9525 |
| PSMC4 | -9044 |
| PSMB4 | -9031 |
| RPS27A | -8850 |
| PSME2 | -8655 |
| PSMC2 | -8605 |
| PSMC3 | -8583 |
| DERL1 | -8464 |
| PSMB8 | -8422 |
| PSMB1 | -7961 |
| PSMD11 | -7679 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ABCB11 | -11664 |
| DERL3 | -11482 |
| PSMB7 | -11240 |
| ABCC6 | -10814 |
| PSMD13 | -10647 |
| DERL2 | -10476 |
| PSMC5 | -9926 |
| ABCC9 | -9773 |
| PSMB3 | -9639 |
| ABCC2 | -9525 |
| PSMC4 | -9044 |
| PSMB4 | -9031 |
| RPS27A | -8850 |
| PSME2 | -8655 |
| PSMC2 | -8605 |
| PSMC3 | -8583 |
| DERL1 | -8464 |
| PSMB8 | -8422 |
| PSMB1 | -7961 |
| PSMD11 | -7679 |
| PSMD12 | -7653 |
| UBC | -7516 |
| ABCC8 | -7301 |
| PSMA1 | -7186 |
| LMBRD1 | -6618 |
| ERLEC1 | -6576 |
| UBB | -6558 |
| PSMD4 | -6474 |
| PSMB5 | -6101 |
| PSMB9 | -5962 |
| PSMA7 | -5784 |
| APOA1 | -5630 |
| PSMD3 | -5582 |
| ABCG8 | -5529 |
| PSMA4 | -5279 |
| PSMB11 | -5123 |
| PSMA2 | -5037 |
| ABCG5 | -4989 |
| PSMB10 | -4396 |
| PSME4 | -4311 |
| PSMA6 | -4225 |
| RNF5 | -3399 |
| ERLIN1 | -3380 |
| PSMD8 | -3004 |
| ABCA1 | -2701 |
| PSMD9 | -2679 |
| PSMD1 | -2198 |
| PSMD14 | -968 |
| KCNJ11 | -471 |
| OS9 | -124 |
| ABCB4 | -102 |
| PSMD5 | 47 |
| PSMA3 | 761 |
| PSMD6 | 1244 |
| PSME3 | 1619 |
| SEM1 | 1961 |
| PSMB2 | 2057 |
| PSMA5 | 2542 |
| PSME1 | 2636 |
| PSMB6 | 2700 |
| SEL1L | 3026 |
| PSMD2 | 3383 |
| PSMC6 | 3448 |
| ABCA3 | 4094 |
| ABCD4 | 4163 |
| UBA52 | 4371 |
| ABCB6 | 4884 |
| PSMC1 | 5036 |
| ERLIN2 | 5170 |
| CFTR | 5194 |
| ABCA12 | 5485 |
| PSMD7 | 5490 |
| VCP | 5713 |
| PSMF1 | 6349 |
| RNF185 | 6483 |
| PSMA8 | 8189 |
REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION_INITIATION
| 1156 | |
|---|---|
| set | REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION_INITIATION |
| setSize | 45 |
| pANOVA | 0.0211 |
| s.dist | 0.199 |
| p.adjustANOVA | 0.7 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| HDAC1 | 8951 |
| TAF1C | 8436 |
| TTF1 | 8112 |
| KAT2B | 8009 |
| ERCC3 | 7495 |
| EHMT2 | 7237 |
| MTA1 | 6936 |
| CHD3 | 6769 |
| HDAC2 | 6411 |
| GTF2H4 | 6008 |
| MNAT1 | 5835 |
| POLR1H | 5049 |
| MBD3 | 5014 |
| POLR1D | 4720 |
| TAF1A | 3396 |
| GTF2H1 | 3263 |
| CHD4 | 3141 |
| ERCC6 | 2674 |
| POLR1A | 2548 |
| RRN3 | 2320 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| HDAC1 | 8951 |
| TAF1C | 8436 |
| TTF1 | 8112 |
| KAT2B | 8009 |
| ERCC3 | 7495 |
| EHMT2 | 7237 |
| MTA1 | 6936 |
| CHD3 | 6769 |
| HDAC2 | 6411 |
| GTF2H4 | 6008 |
| MNAT1 | 5835 |
| POLR1H | 5049 |
| MBD3 | 5014 |
| POLR1D | 4720 |
| TAF1A | 3396 |
| GTF2H1 | 3263 |
| CHD4 | 3141 |
| ERCC6 | 2674 |
| POLR1A | 2548 |
| RRN3 | 2320 |
| MTA3 | 2133 |
| POLR1F | 1716 |
| POLR1B | 1432 |
| POLR2H | 760 |
| POLR2F | 722 |
| POLR1C | 574 |
| TAF1B | 444 |
| TAF1D | -185 |
| ERCC2 | -1316 |
| GATAD2B | -1799 |
| KAT2A | -2622 |
| MTA2 | -2680 |
| POLR2K | -2963 |
| POLR1G | -3235 |
| RBBP4 | -3719 |
| GTF2H3 | -3987 |
| CCNH | -4547 |
| CDK7 | -4798 |
| POLR1E | -5181 |
| GATAD2A | -5799 |
| UBTF | -7173 |
| GTF2H5 | -8690 |
| POLR2L | -8763 |
| POLR2E | -9019 |
| TBP | -9896 |
REACTOME_DAP12_SIGNALING
| 485 | |
|---|---|
| set | REACTOME_DAP12_SIGNALING |
| setSize | 27 |
| pANOVA | 0.0216 |
| s.dist | -0.255 |
| p.adjustANOVA | 0.7 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TREM2 | -12299 |
| TYROBP | -12086 |
| KLRD1 | -11840 |
| NRAS | -10906 |
| LCP2 | -10227 |
| GRB2 | -9911 |
| B2M | -9168 |
| VAV2 | -6903 |
| PIK3CA | -6283 |
| PIK3R2 | -6034 |
| PIK3R1 | -5692 |
| RAC1 | -5651 |
| SYK | -5379 |
| HLA-E | -5359 |
| KLRK1 | -4600 |
| LCK | -2552 |
| SHC1 | -1802 |
| GRAP2 | -1248 |
| FYN | -1185 |
| PLCG1 | -1095 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TREM2 | -12299 |
| TYROBP | -12086 |
| KLRD1 | -11840 |
| NRAS | -10906 |
| LCP2 | -10227 |
| GRB2 | -9911 |
| B2M | -9168 |
| VAV2 | -6903 |
| PIK3CA | -6283 |
| PIK3R2 | -6034 |
| PIK3R1 | -5692 |
| RAC1 | -5651 |
| SYK | -5379 |
| HLA-E | -5359 |
| KLRK1 | -4600 |
| LCK | -2552 |
| SHC1 | -1802 |
| GRAP2 | -1248 |
| FYN | -1185 |
| PLCG1 | -1095 |
| KRAS | 94 |
| HRAS | 462 |
| VAV3 | 2014 |
| PIK3CB | 2393 |
| LAT | 2546 |
| PLCG2 | 3580 |
| SOS1 | 4627 |
REACTOME_DNA_REPAIR
| 1168 | |
|---|---|
| set | REACTOME_DNA_REPAIR |
| setSize | 321 |
| pANOVA | 0.0217 |
| s.dist | 0.0745 |
| p.adjustANOVA | 0.7 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| POLR2J | 9345 |
| H3-4 | 9174 |
| FAN1 | 9096 |
| H2BC15 | 8813 |
| POLD2 | 8803 |
| ISG15 | 8677 |
| CLSPN | 8521 |
| COPS8 | 8267 |
| POLR2A | 8039 |
| PARG | 7955 |
| COPS4 | 7952 |
| PPIE | 7929 |
| POLE | 7895 |
| PIAS4 | 7741 |
| BRCA1 | 7712 |
| NSD2 | 7697 |
| SUMO3 | 7679 |
| RNF168 | 7582 |
| ERCC3 | 7495 |
| POLK | 7351 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| POLR2J | 9345.0 |
| H3-4 | 9174.0 |
| FAN1 | 9096.0 |
| H2BC15 | 8813.0 |
| POLD2 | 8803.0 |
| ISG15 | 8677.0 |
| CLSPN | 8521.0 |
| COPS8 | 8267.0 |
| POLR2A | 8039.0 |
| PARG | 7955.0 |
| COPS4 | 7952.0 |
| PPIE | 7929.0 |
| POLE | 7895.0 |
| PIAS4 | 7741.0 |
| BRCA1 | 7712.0 |
| NSD2 | 7697.0 |
| SUMO3 | 7679.0 |
| RNF168 | 7582.0 |
| ERCC3 | 7495.0 |
| POLK | 7351.0 |
| PRKDC | 7319.0 |
| UBA7 | 7274.0 |
| ERCC8 | 7272.0 |
| H2AX | 7107.0 |
| NFRKB | 7093.0 |
| FANCA | 7091.0 |
| UVSSA | 7082.0 |
| PPP5C | 7074.0 |
| XRCC2 | 7053.0 |
| CCNA2 | 7041.0 |
| H2BC9 | 6991.5 |
| GEN1 | 6972.0 |
| MSH3 | 6951.0 |
| TERF1 | 6887.0 |
| RNF8 | 6827.5 |
| TIPIN | 6767.0 |
| POLL | 6628.0 |
| H4C13 | 6594.0 |
| RAD9A | 6488.0 |
| BAP1 | 6484.0 |
| YY1 | 6457.0 |
| PARP1 | 6374.0 |
| RFC1 | 6366.0 |
| NEIL2 | 6356.0 |
| CUL4A | 6351.0 |
| GPS1 | 6293.0 |
| H4C11 | 6170.0 |
| PCLAF | 6153.0 |
| H4C16 | 6148.0 |
| GTF2H4 | 6008.0 |
| SLX4 | 5900.0 |
| MNAT1 | 5835.0 |
| RAD51B | 5819.0 |
| HERC2 | 5818.0 |
| DDB1 | 5807.0 |
| HUS1 | 5797.0 |
| FANCL | 5753.0 |
| VCP | 5713.0 |
| RAD18 | 5585.0 |
| FAAP24 | 5566.0 |
| MSH2 | 5564.0 |
| H4C4 | 5517.0 |
| UBE2V2 | 5425.0 |
| H4C3 | 5331.0 |
| ACTR8 | 5244.0 |
| UBE2L6 | 5145.0 |
| MDC1 | 5118.0 |
| UNG | 5092.0 |
| POLM | 5083.0 |
| MLH1 | 5071.0 |
| FAAP100 | 5022.0 |
| RPA1 | 4991.0 |
| H2AC4 | 4441.0 |
| RAD9B | 4435.0 |
| DNA2 | 4434.0 |
| INO80 | 4398.0 |
| FANCF | 4379.0 |
| UBA52 | 4371.0 |
| TP53 | 4288.0 |
| UBE2I | 4247.0 |
| FANCC | 4140.0 |
| NBN | 4116.0 |
| EP300 | 3970.0 |
| RMI2 | 3946.0 |
| ASCC2 | 3874.0 |
| ACD | 3865.5 |
| POT1 | 3791.0 |
| APBB1 | 3780.0 |
| COPS6 | 3739.0 |
| REV1 | 3624.0 |
| GTF2H1 | 3263.0 |
| PARP2 | 3229.0 |
| CCNA1 | 3223.0 |
| KDM4B | 3155.0 |
| INO80B | 3094.0 |
| ATR | 3006.0 |
| H2BC12 | 2936.0 |
| MUTYH | 2856.0 |
| PAXIP1 | 2855.0 |
| BRIP1 | 2839.0 |
| LIG1 | 2777.0 |
| SIRT6 | 2766.0 |
| ERCC6 | 2674.0 |
| POLR2B | 2622.0 |
| AQR | 2583.0 |
| ACTL6A | 2529.0 |
| RBBP8 | 2493.0 |
| BABAM2 | 2414.0 |
| RHNO1 | 2378.0 |
| COPS3 | 2360.0 |
| INO80C | 2331.0 |
| TFPT | 2230.0 |
| CHD1L | 2199.0 |
| DCLRE1C | 2195.0 |
| OGG1 | 2176.0 |
| UBE2T | 2137.0 |
| RAD23B | 2127.0 |
| ALKBH3 | 2104.0 |
| NEIL1 | 2094.0 |
| H4C12 | 1999.0 |
| SEM1 | 1961.0 |
| NEIL3 | 1938.0 |
| PNKP | 1841.0 |
| XAB2 | 1836.0 |
| RNF4 | 1806.0 |
| H2BC8 | 1727.0 |
| ERCC4 | 1690.0 |
| POLR2G | 1673.0 |
| RFC5 | 1629.0 |
| XRCC3 | 1613.0 |
| WRN | 1603.0 |
| RMI1 | 1440.0 |
| XRCC6 | 1347.0 |
| H2AC18 | 1298.5 |
| H2AC19 | 1298.5 |
| USP10 | 1163.0 |
| H2BC10 | 1052.0 |
| FANCI | 977.0 |
| TIMELESS | 938.0 |
| COPS7B | 907.0 |
| TOP3A | 882.0 |
| MGMT | 841.0 |
| PCNA | 815.0 |
| TERF2 | 772.0 |
| POLR2H | 760.0 |
| POLR2F | 722.0 |
| MAPK8 | 717.0 |
| FEN1 | 657.0 |
| KDM4A | 600.0 |
| ASCC3 | 557.0 |
| ATM | 437.0 |
| RAD51AP1 | 429.0 |
| UFD1 | 406.0 |
| POLR2D | 313.0 |
| RNF111 | 286.0 |
| SPIDR | -28.0 |
| EYA4 | -100.0 |
| NPLOC4 | -115.0 |
| SMARCA5 | -116.0 |
| POLN | -122.0 |
| ERCC5 | -215.0 |
| H2BC13 | -344.0 |
| EYA1 | -426.0 |
| PPP4R2 | -432.0 |
| KAT5 | -454.0 |
| XRCC1 | -493.0 |
| POLB | -508.0 |
| RFC3 | -509.0 |
| COPS7A | -541.0 |
| UIMC1 | -598.0 |
| SMUG1 | -637.0 |
| ELL | -697.0 |
| XRCC5 | -707.0 |
| RAD51C | -900.0 |
| UBE2B | -907.0 |
| NTHL1 | -945.0 |
| TDG | -1014.0 |
| RUVBL1 | -1016.0 |
| ALKBH2 | -1056.0 |
| H2AC6 | -1218.0 |
| POLE3 | -1246.0 |
| ERCC2 | -1316.0 |
| TP53BP1 | -1353.0 |
| POLD1 | -1514.0 |
| TDP2 | -1552.0 |
| FAAP20 | -1601.0 |
| REV3L | -1626.0 |
| H2AC8 | -1791.0 |
| RIF1 | -1994.0 |
| DCLRE1A | -1999.0 |
| MSH6 | -2013.0 |
| H2BC21 | -2245.0 |
| RCHY1 | -2298.0 |
| ACTR5 | -2348.0 |
| ABRAXAS1 | -2396.0 |
| EME2 | -2413.0 |
| H4C2 | -2471.0 |
| ATRIP | -2487.0 |
| H4C9 | -2491.0 |
| EXO1 | -2529.0 |
| TERF2IP | -2540.0 |
| KPNA2 | -2646.0 |
| MUS81 | -2726.0 |
| MAD2L2 | -2794.0 |
| XPC | -2934.0 |
| POLR2K | -2963.0 |
| TDP1 | -3073.0 |
| CDK2 | -3257.0 |
| H2AZ1 | -3348.0 |
| RAD51D | -3376.0 |
| ABL1 | -3561.0 |
| MCRS1 | -3610.0 |
| ASCC1 | -3622.0 |
| XPA | -3936.0 |
| ALKBH5 | -3939.0 |
| POLD3 | -3945.0 |
| RAD52 | -3961.0 |
| ZNF830 | -3973.0 |
| GTF2H3 | -3987.0 |
| FANCG | -4045.0 |
| TRIM25 | -4067.0 |
| H2AJ | -4124.0 |
| LIG3 | -4256.0 |
| H2BC17 | -4265.0 |
| RAD17 | -4379.0 |
| PIAS1 | -4500.0 |
| H2AC20 | -4507.0 |
| CCNH | -4547.0 |
| SUMO2 | -4761.0 |
| TOPBP1 | -4787.0 |
| CDK7 | -4798.0 |
| CHEK1 | -4836.0 |
| POLH | -4885.0 |
| EYA2 | -4940.0 |
| BAZ1B | -4966.0 |
| H2BC4 | -5269.0 |
| LIG4 | -5306.0 |
| DTL | -5364.0 |
| BARD1 | -5377.0 |
| RFC2 | -5440.0 |
| USP7 | -5475.0 |
| H4C5 | -5492.0 |
| PPP4C | -5556.0 |
| H2BC26 | -5603.0 |
| POLQ | -5682.0 |
| WDR48 | -5709.0 |
| POLE4 | -5793.0 |
| H2BC3 | -5808.0 |
| APEX1 | -5933.0 |
| USP43 | -5997.0 |
| BRCA2 | -6067.0 |
| TINF2 | -6158.0 |
| XRCC4 | -6265.0 |
| DCLRE1B | -6356.0 |
| RBX1 | -6489.0 |
| INO80D | -6495.0 |
| UBB | -6558.0 |
| FANCM | -6569.0 |
| UBXN1 | -6597.0 |
| RPA3 | -6683.0 |
| PRPF19 | -6715.0 |
| H2BC5 | -6716.0 |
| BLM | -6759.0 |
| MRE11 | -6761.0 |
| HMGN1 | -6867.0 |
| ISY1 | -6891.0 |
| H2BC1 | -7004.0 |
| INO80E | -7041.0 |
| POLR2I | -7081.0 |
| EYA3 | -7144.0 |
| PMS2 | -7233.0 |
| H2AZ2 | -7419.0 |
| COPS2 | -7461.0 |
| POLI | -7464.0 |
| TCEA1 | -7470.0 |
| UBC | -7516.0 |
| PALB2 | -7590.0 |
| FTO | -7806.0 |
| ADPRS | -7839.0 |
| COPS5 | -8093.0 |
| USP45 | -8150.0 |
| CHEK2 | -8164.0 |
| USP1 | -8188.0 |
| RFC4 | -8250.0 |
| RPA2 | -8285.0 |
| CENPS | -8315.0 |
| FANCE | -8332.0 |
| POLE2 | -8399.0 |
| SPRTN | -8480.0 |
| POLR2C | -8531.0 |
| SUMO1 | -8595.0 |
| GTF2H5 | -8690.0 |
| POLR2L | -8763.0 |
| RAD23A | -8826.0 |
| RPS27A | -8850.0 |
| FANCD2 | -8906.0 |
| POLR2E | -9019.0 |
| RAD1 | -9205.0 |
| MBD4 | -9314.0 |
| PIAS3 | -9380.0 |
| H2BC6 | -9394.0 |
| RAD51 | -9561.0 |
| ERCC1 | -9742.0 |
| H2BC11 | -9747.0 |
| MPG | -9793.0 |
| POLD4 | -9963.0 |
| ACTB | -10011.0 |
| RAD50 | -10110.0 |
| DDB2 | -10194.0 |
| H4C6 | -10210.0 |
| UBE2N | -10604.0 |
| RTEL1 | -10653.0 |
| BABAM1 | -10663.0 |
| EME1 | -10915.0 |
| H2AC7 | -11040.5 |
| H2BC7 | -11040.5 |
| NHEJ1 | -11068.0 |
| H4C1 | -11106.0 |
| H2AC14 | -11332.0 |
| H4C8 | -11506.0 |
| H2BC14 | -11709.0 |
Here is the session info with all the versions of packages used.
sessionInfo()## R version 4.3.2 (2023-10-31)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.3 LTS
##
## Matrix products: default
## BLAS: /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so; LAPACK version 3.10.0
##
## locale:
## [1] LC_CTYPE=en_US.UTF-8 LC_NUMERIC=C
## [3] LC_TIME=en_US.UTF-8 LC_COLLATE=en_US.UTF-8
## [5] LC_MONETARY=en_US.UTF-8 LC_MESSAGES=en_US.UTF-8
## [7] LC_PAPER=en_US.UTF-8 LC_NAME=C
## [9] LC_ADDRESS=C LC_TELEPHONE=C
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C
##
## time zone: Etc/UTC
## tzcode source: system (glibc)
##
## attached base packages:
## [1] parallel stats4 stats graphics grDevices utils datasets
## [8] methods base
##
## other attached packages:
## [1] pkgload_1.3.3
## [2] GGally_2.2.0
## [3] ggplot2_3.4.4
## [4] reshape2_1.4.4
## [5] gtools_3.9.5
## [6] tibble_3.2.1
## [7] dplyr_1.1.4
## [8] echarts4r_0.4.5
## [9] png_0.1-8
## [10] gridExtra_2.3
## [11] missMethyl_1.36.0
## [12] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.1
## [13] beeswarm_0.4.0
## [14] kableExtra_1.3.4
## [15] gplots_3.1.3
## [16] mitch_1.15.0
## [17] tictoc_1.2
## [18] HGNChelper_0.8.1
## [19] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [20] IlluminaHumanMethylation450kmanifest_0.4.0
## [21] minfi_1.48.0
## [22] bumphunter_1.44.0
## [23] locfit_1.5-9.8
## [24] iterators_1.0.14
## [25] foreach_1.5.2
## [26] Biostrings_2.70.1
## [27] XVector_0.42.0
## [28] SummarizedExperiment_1.32.0
## [29] Biobase_2.62.0
## [30] MatrixGenerics_1.14.0
## [31] matrixStats_1.2.0
## [32] GenomicRanges_1.54.1
## [33] GenomeInfoDb_1.38.2
## [34] IRanges_2.36.0
## [35] S4Vectors_0.40.2
## [36] BiocGenerics_0.48.1
## [37] eulerr_7.0.0
## [38] limma_3.58.1
##
## loaded via a namespace (and not attached):
## [1] splines_4.3.2 later_1.3.2
## [3] BiocIO_1.12.0 bitops_1.0-7
## [5] filelock_1.0.3 preprocessCore_1.64.0
## [7] XML_3.99-0.16 lifecycle_1.0.4
## [9] lattice_0.22-5 MASS_7.3-60
## [11] base64_2.0.1 scrime_1.3.5
## [13] magrittr_2.0.3 sass_0.4.8
## [15] rmarkdown_2.25 jquerylib_0.1.4
## [17] yaml_2.3.8 httpuv_1.6.13
## [19] doRNG_1.8.6 askpass_1.2.0
## [21] DBI_1.1.3 RColorBrewer_1.1-3
## [23] abind_1.4-5 zlibbioc_1.48.0
## [25] rvest_1.0.3 quadprog_1.5-8
## [27] purrr_1.0.2 RCurl_1.98-1.13
## [29] rappdirs_0.3.3 GenomeInfoDbData_1.2.11
## [31] genefilter_1.84.0 annotate_1.80.0
## [33] svglite_2.1.3 DelayedMatrixStats_1.24.0
## [35] codetools_0.2-19 DelayedArray_0.28.0
## [37] xml2_1.3.6 tidyselect_1.2.0
## [39] beanplot_1.3.1 BiocFileCache_2.10.1
## [41] webshot_0.5.5 illuminaio_0.44.0
## [43] GenomicAlignments_1.38.0 jsonlite_1.8.8
## [45] multtest_2.58.0 ellipsis_0.3.2
## [47] survival_3.5-7 systemfonts_1.0.5
## [49] tools_4.3.2 progress_1.2.3
## [51] Rcpp_1.0.11 glue_1.6.2
## [53] SparseArray_1.2.2 xfun_0.41
## [55] HDF5Array_1.30.0 withr_2.5.2
## [57] fastmap_1.1.1 rhdf5filters_1.14.1
## [59] fansi_1.0.6 openssl_2.1.1
## [61] caTools_1.18.2 digest_0.6.33
## [63] R6_2.5.1 mime_0.12
## [65] colorspace_2.1-0 biomaRt_2.58.0
## [67] RSQLite_2.3.4 utf8_1.2.4
## [69] tidyr_1.3.0 generics_0.1.3
## [71] data.table_1.14.10 rtracklayer_1.62.0
## [73] prettyunits_1.2.0 httr_1.4.7
## [75] htmlwidgets_1.6.4 S4Arrays_1.2.0
## [77] ggstats_0.5.1 pkgconfig_2.0.3
## [79] gtable_0.3.4 blob_1.2.4
## [81] siggenes_1.76.0 htmltools_0.5.7
## [83] scales_1.3.0 rstudioapi_0.15.0
## [85] knitr_1.45 tzdb_0.4.0
## [87] rjson_0.2.21 nlme_3.1-163
## [89] curl_5.2.0 org.Hs.eg.db_3.18.0
## [91] cachem_1.0.8 rhdf5_2.46.1
## [93] stringr_1.5.1 KernSmooth_2.23-22
## [95] AnnotationDbi_1.64.1 restfulr_0.0.15
## [97] GEOquery_2.70.0 pillar_1.9.0
## [99] grid_4.3.2 reshape_0.8.9
## [101] vctrs_0.6.5 promises_1.2.1
## [103] dbplyr_2.4.0 xtable_1.8-4
## [105] evaluate_0.23 readr_2.1.4
## [107] GenomicFeatures_1.54.1 cli_3.6.2
## [109] compiler_4.3.2 Rsamtools_2.18.0
## [111] rlang_1.1.2 crayon_1.5.2
## [113] rngtools_1.5.2 nor1mix_1.3-2
## [115] mclust_6.0.1 plyr_1.8.9
## [117] stringi_1.8.3 viridisLite_0.4.2
## [119] BiocParallel_1.36.0 munsell_0.5.0
## [121] Matrix_1.6-1.1 hms_1.1.3
## [123] sparseMatrixStats_1.14.0 bit64_4.0.5
## [125] Rhdf5lib_1.24.1 KEGGREST_1.42.0
## [127] statmod_1.5.0 shiny_1.8.0
## [129] highr_0.10 memoise_2.0.1
## [131] bslib_0.6.1 bit_4.0.5END of report