date generated: 2024-01-18

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch
x
A1BG -0.0130717
A1BG-AS1 -0.0190113
A1CF -0.0138868
A2M -0.0064520
A2M-AS1 0.0242870
A2ML1 0.0018354

Here are some metrics about the input data profile:

Profiling data metrics
Profile metrics
num_genesets 1654
num_genes_in_profile 22007
duplicated_genes_present 0
num_profile_genes_in_sets 10383
num_profile_genes_not_in_sets 11624

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets: c2.cp.reactome.v2023.1.Hs.symbols.gmt
Gene set metrics
Gene sets metrics
num_genesets 1654
num_genesets_excluded 365
num_genesets_included 1289

Differential pathway expression


Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

## Warning in kable_styling(., "hover", full_width = FALSE): Please specify format
## in kable. kableExtra can customize either HTML or LaTeX outputs. See
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set setSize pANOVA s.dist p.adjustANOVA
REACTOME SENSORY PERCEPTION 555 1.19e-18 -0.2190 1.96e-15
REACTOME OLFACTORY SIGNALING PATHWAY 348 3.54e-15 -0.2450 2.91e-12
REACTOME NEUTROPHIL DEGRANULATION 460 7.27e-13 0.1950 3.98e-10
REACTOME INNATE IMMUNE SYSTEM 1002 3.05e-09 0.1110 1.25e-06
REACTOME CELLULAR RESPONSES TO STIMULI 779 5.70e-05 0.0848 1.87e-02
REACTOME RNA POLYMERASE II TRANSCRIPTION 1336 8.17e-05 0.0642 2.24e-02
REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR 11 1.23e-03 0.5630 2.57e-01
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM 688 1.25e-03 0.0722 2.57e-01
REACTOME SIGNALING BY INTERLEUKINS 444 2.06e-03 0.0853 3.00e-01
REACTOME ACYL CHAIN REMODELLING OF PC 27 2.25e-03 -0.3400 3.00e-01
REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS 188 2.31e-03 0.1290 3.00e-01
REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX 134 2.33e-03 -0.1520 3.00e-01
REACTOME PROGRAMMED CELL DEATH 204 2.70e-03 0.1220 3.00e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES 11 2.87e-03 0.5190 3.00e-01
REACTOME METABOLISM OF RNA 675 2.95e-03 0.0671 3.00e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES 10 3.25e-03 0.5380 3.00e-01
REACTOME INTERLEUKIN 10 SIGNALING 43 3.33e-03 0.2590 3.00e-01
REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS 55 3.49e-03 -0.2280 3.00e-01
REACTOME TRANSCRIPTIONAL REGULATION BY TP53 351 3.54e-03 0.0906 3.00e-01
REACTOME NGF STIMULATED TRANSCRIPTION 38 3.65e-03 0.2720 3.00e-01
REACTOME VISUAL PHOTOTRANSDUCTION 93 3.97e-03 -0.1730 3.10e-01
REACTOME EXTRACELLULAR MATRIX ORGANIZATION 291 4.32e-03 -0.0972 3.10e-01
REACTOME INTERLEUKIN 1 SIGNALING 110 4.47e-03 0.1570 3.10e-01
REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION 12 4.87e-03 0.4690 3.10e-01
REACTOME KERATINIZATION 210 4.91e-03 -0.1130 3.10e-01
REACTOME ECM PROTEOGLYCANS 73 4.97e-03 -0.1900 3.10e-01
REACTOME SHC1 EVENTS IN EGFR SIGNALING 14 5.09e-03 0.4320 3.10e-01
REACTOME LAMININ INTERACTIONS 28 6.59e-03 -0.2970 3.80e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING 11 7.17e-03 0.4680 3.80e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION 89 7.21e-03 0.1650 3.80e-01
REACTOME CARGO CONCENTRATION IN THE ER 32 7.35e-03 0.2740 3.80e-01
REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS 21 7.77e-03 0.3360 3.80e-01
REACTOME KEAP1 NFE2L2 PATHWAY 104 8.21e-03 0.1500 3.80e-01
REACTOME MATURATION OF PROTEIN 3A 9 8.22e-03 0.5090 3.80e-01
REACTOME DIGESTION AND ABSORPTION 22 8.25e-03 -0.3250 3.80e-01
REACTOME SHC1 EVENTS IN ERBB2 SIGNALING 22 8.43e-03 0.3240 3.80e-01
REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS 29 8.98e-03 0.2800 3.80e-01
REACTOME ASPIRIN ADME 42 9.00e-03 -0.2330 3.80e-01
REACTOME APOPTOSIS 173 9.13e-03 0.1150 3.80e-01
REACTOME PYRIMIDINE SALVAGE 10 9.40e-03 0.4740 3.80e-01
REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS 66 9.49e-03 -0.1850 3.80e-01
REACTOME DAP12 INTERACTIONS 37 9.89e-03 0.2450 3.87e-01
REACTOME ION TRANSPORT BY P TYPE ATPASES 51 1.02e-02 -0.2080 3.90e-01
REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB 5 1.11e-02 0.6560 4.07e-01
REACTOME TRANS GOLGI NETWORK VESICLE BUDDING 67 1.13e-02 0.1790 4.07e-01
REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS 5 1.16e-02 -0.6520 4.07e-01
REACTOME UNFOLDED PROTEIN RESPONSE UPR 88 1.17e-02 0.1560 4.07e-01
REACTOME ANTIMICROBIAL PEPTIDES 76 1.20e-02 0.1670 4.07e-01
REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY 72 1.23e-02 0.1710 4.07e-01
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL 122 1.24e-02 0.1310 4.07e-01


Results (complete table)


Click HERE to show results for all gene sets

Complete results
set setSize pANOVA s.dist p.adjustANOVA
REACTOME SENSORY PERCEPTION 555 1.19e-18 -0.219000 1.96e-15
REACTOME OLFACTORY SIGNALING PATHWAY 348 3.54e-15 -0.245000 2.91e-12
REACTOME NEUTROPHIL DEGRANULATION 460 7.27e-13 0.195000 3.98e-10
REACTOME INNATE IMMUNE SYSTEM 1002 3.05e-09 0.111000 1.25e-06
REACTOME CELLULAR RESPONSES TO STIMULI 779 5.70e-05 0.084800 1.87e-02
REACTOME RNA POLYMERASE II TRANSCRIPTION 1336 8.17e-05 0.064200 2.24e-02
REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR 11 1.23e-03 0.563000 2.57e-01
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM 688 1.25e-03 0.072200 2.57e-01
REACTOME SIGNALING BY INTERLEUKINS 444 2.06e-03 0.085300 3.00e-01
REACTOME ACYL CHAIN REMODELLING OF PC 27 2.25e-03 -0.340000 3.00e-01
REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS 188 2.31e-03 0.129000 3.00e-01
REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX 134 2.33e-03 -0.152000 3.00e-01
REACTOME PROGRAMMED CELL DEATH 204 2.70e-03 0.122000 3.00e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES 11 2.87e-03 0.519000 3.00e-01
REACTOME METABOLISM OF RNA 675 2.95e-03 0.067100 3.00e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES 10 3.25e-03 0.538000 3.00e-01
REACTOME INTERLEUKIN 10 SIGNALING 43 3.33e-03 0.259000 3.00e-01
REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS 55 3.49e-03 -0.228000 3.00e-01
REACTOME TRANSCRIPTIONAL REGULATION BY TP53 351 3.54e-03 0.090600 3.00e-01
REACTOME NGF STIMULATED TRANSCRIPTION 38 3.65e-03 0.272000 3.00e-01
REACTOME VISUAL PHOTOTRANSDUCTION 93 3.97e-03 -0.173000 3.10e-01
REACTOME EXTRACELLULAR MATRIX ORGANIZATION 291 4.32e-03 -0.097200 3.10e-01
REACTOME INTERLEUKIN 1 SIGNALING 110 4.47e-03 0.157000 3.10e-01
REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION 12 4.87e-03 0.469000 3.10e-01
REACTOME KERATINIZATION 210 4.91e-03 -0.113000 3.10e-01
REACTOME ECM PROTEOGLYCANS 73 4.97e-03 -0.190000 3.10e-01
REACTOME SHC1 EVENTS IN EGFR SIGNALING 14 5.09e-03 0.432000 3.10e-01
REACTOME LAMININ INTERACTIONS 28 6.59e-03 -0.297000 3.80e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING 11 7.17e-03 0.468000 3.80e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION 89 7.21e-03 0.165000 3.80e-01
REACTOME CARGO CONCENTRATION IN THE ER 32 7.35e-03 0.274000 3.80e-01
REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS 21 7.77e-03 0.336000 3.80e-01
REACTOME KEAP1 NFE2L2 PATHWAY 104 8.21e-03 0.150000 3.80e-01
REACTOME MATURATION OF PROTEIN 3A 9 8.22e-03 0.509000 3.80e-01
REACTOME DIGESTION AND ABSORPTION 22 8.25e-03 -0.325000 3.80e-01
REACTOME SHC1 EVENTS IN ERBB2 SIGNALING 22 8.43e-03 0.324000 3.80e-01
REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS 29 8.98e-03 0.280000 3.80e-01
REACTOME ASPIRIN ADME 42 9.00e-03 -0.233000 3.80e-01
REACTOME APOPTOSIS 173 9.13e-03 0.115000 3.80e-01
REACTOME PYRIMIDINE SALVAGE 10 9.40e-03 0.474000 3.80e-01
REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS 66 9.49e-03 -0.185000 3.80e-01
REACTOME DAP12 INTERACTIONS 37 9.89e-03 0.245000 3.87e-01
REACTOME ION TRANSPORT BY P TYPE ATPASES 51 1.02e-02 -0.208000 3.90e-01
REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB 5 1.11e-02 0.656000 4.07e-01
REACTOME TRANS GOLGI NETWORK VESICLE BUDDING 67 1.13e-02 0.179000 4.07e-01
REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS 5 1.16e-02 -0.652000 4.07e-01
REACTOME UNFOLDED PROTEIN RESPONSE UPR 88 1.17e-02 0.156000 4.07e-01
REACTOME ANTIMICROBIAL PEPTIDES 76 1.20e-02 0.167000 4.07e-01
REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY 72 1.23e-02 0.171000 4.07e-01
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL 122 1.24e-02 0.131000 4.07e-01
REACTOME REPRESSION OF WNT TARGET GENES 14 1.33e-02 -0.382000 4.29e-01
REACTOME DIGESTION 17 1.46e-02 -0.342000 4.37e-01
REACTOME DRUG ADME 103 1.46e-02 -0.139000 4.37e-01
REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS 312 1.48e-02 0.080200 4.37e-01
REACTOME CREATION OF C4 AND C2 ACTIVATORS 14 1.49e-02 -0.376000 4.37e-01
REACTOME INITIAL TRIGGERING OF COMPLEMENT 21 1.49e-02 -0.307000 4.37e-01
REACTOME FLT3 SIGNALING 38 1.60e-02 0.226000 4.48e-01
REACTOME INTERACTION BETWEEN L1 AND ANKYRINS 30 1.67e-02 -0.252000 4.48e-01
REACTOME ONCOGENE INDUCED SENESCENCE 35 1.74e-02 0.232000 4.48e-01
REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS 418 1.77e-02 0.067600 4.48e-01
REACTOME SHC1 EVENTS IN ERBB4 SIGNALING 14 1.79e-02 0.365000 4.48e-01
REACTOME SIGNALING BY SCF KIT 42 1.80e-02 0.211000 4.48e-01
REACTOME METABOLISM OF NUCLEOTIDES 94 1.82e-02 0.141000 4.48e-01
REACTOME ACYL CHAIN REMODELLING OF PG 18 1.85e-02 -0.321000 4.48e-01
REACTOME NUCLEAR EVENTS MEDIATED BY NFE2L2 77 1.85e-02 0.155000 4.48e-01
REACTOME DIGESTION OF DIETARY CARBOHYDRATE 6 1.89e-02 -0.553000 4.48e-01
REACTOME CELL CYCLE 666 1.94e-02 0.053100 4.48e-01
REACTOME MET ACTIVATES PTK2 SIGNALING 30 1.99e-02 -0.246000 4.48e-01
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS 161 2.00e-02 0.106000 4.48e-01
REACTOME SIGNALING BY PDGFR IN DISEASE 20 2.01e-02 0.300000 4.48e-01
REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION 19 2.03e-02 -0.308000 4.48e-01
REACTOME IRAK4 DEFICIENCY TLR2 4 17 2.06e-02 0.324000 4.48e-01
REACTOME SYNTHESIS OF 5 EICOSATETRAENOIC ACIDS 9 2.08e-02 0.445000 4.48e-01
REACTOME TOLL LIKE RECEPTOR CASCADES 158 2.08e-02 0.107000 4.48e-01
REACTOME INTERLEUKIN 1 FAMILY SIGNALING 146 2.08e-02 0.111000 4.48e-01
REACTOME ACYL CHAIN REMODELLING OF PS 22 2.09e-02 -0.284000 4.48e-01
REACTOME INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES 28 2.10e-02 0.252000 4.48e-01
REACTOME REGULATION OF TP53 ACTIVITY 156 2.19e-02 0.106000 4.54e-01
REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES 34 2.20e-02 0.227000 4.54e-01
REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS 51 2.21e-02 0.185000 4.54e-01
REACTOME ADAPTIVE IMMUNE SYSTEM 729 2.27e-02 0.049500 4.61e-01
REACTOME CELL CYCLE CHECKPOINTS 284 2.35e-02 0.078100 4.70e-01
REACTOME METAL ION SLC TRANSPORTERS 23 2.38e-02 0.272000 4.70e-01
REACTOME REGULATION OF GENE EXPRESSION IN ENDOCRINE COMMITTED NEUROG3 PROGENITOR CELLS 5 2.62e-02 0.574000 4.93e-01
REACTOME NUCLEOTIDE SALVAGE 21 2.63e-02 0.280000 4.93e-01
REACTOME TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS 29 2.64e-02 0.238000 4.93e-01
REACTOME INTERLEUKIN 12 FAMILY SIGNALING 53 2.67e-02 0.176000 4.93e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH RAS 9 2.68e-02 0.426000 4.93e-01
REACTOME RAC2 GTPASE CYCLE 81 2.70e-02 0.142000 4.93e-01
REACTOME INTERLEUKIN 2 SIGNALING 11 2.71e-02 0.385000 4.93e-01
REACTOME SIGNALING BY PTK6 54 2.77e-02 0.173000 4.93e-01
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION 250 2.80e-02 0.080700 4.93e-01
REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS 6 2.82e-02 0.517000 4.93e-01
REACTOME TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS 55 2.82e-02 0.171000 4.93e-01
REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS 83 2.88e-02 0.139000 4.98e-01
REACTOME SARS COV 1 INFECTION 136 2.95e-02 0.108000 5.00e-01
REACTOME FLT3 SIGNALING IN DISEASE 28 2.96e-02 0.238000 5.00e-01
REACTOME CYCLIN D ASSOCIATED EVENTS IN G1 46 2.99e-02 0.185000 5.00e-01
REACTOME SYNTHESIS OF PG 8 3.04e-02 0.442000 5.00e-01
REACTOME MATURATION OF SARS COV 2 SPIKE PROTEIN 35 3.05e-02 0.211000 5.00e-01
REACTOME G1 S DNA DAMAGE CHECKPOINTS 67 3.15e-02 0.152000 5.02e-01
REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION 31 3.20e-02 0.223000 5.02e-01
REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES 18 3.25e-02 -0.291000 5.02e-01
REACTOME GAB1 SIGNALOSOME 17 3.29e-02 0.299000 5.02e-01
REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION 145 3.31e-02 0.103000 5.02e-01
REACTOME VXPX CARGO TARGETING TO CILIUM 20 3.33e-02 -0.275000 5.02e-01
REACTOME ERYTHROPOIETIN ACTIVATES RAS 14 3.37e-02 0.328000 5.02e-01
REACTOME G2 M DNA DAMAGE CHECKPOINT 90 3.39e-02 0.129000 5.02e-01
REACTOME SENSORY PERCEPTION OF TASTE 47 3.39e-02 -0.179000 5.02e-01
REACTOME G2 M CHECKPOINTS 162 3.41e-02 0.096500 5.02e-01
REACTOME IRAK1 RECRUITS IKK COMPLEX 12 3.49e-02 0.352000 5.02e-01
REACTOME LYSOSOME VESICLE BIOGENESIS 33 3.51e-02 0.212000 5.02e-01
REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS 18 3.63e-02 -0.285000 5.02e-01
REACTOME ORGANIC ANION TRANSPORT 5 3.64e-02 -0.540000 5.02e-01
REACTOME ACYL CHAIN REMODELLING OF PI 17 3.65e-02 -0.293000 5.02e-01
REACTOME SIGNALING BY FGFR1 IN DISEASE 38 3.66e-02 0.196000 5.02e-01
REACTOME IRON UPTAKE AND TRANSPORT 56 3.68e-02 0.161000 5.02e-01
REACTOME INTERLEUKIN 15 SIGNALING 13 3.68e-02 0.334000 5.02e-01
REACTOME PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING 11 3.69e-02 -0.363000 5.02e-01
REACTOME SENSORY PROCESSING OF SOUND 72 3.72e-02 -0.142000 5.02e-01
REACTOME SIGNALING BY EGFR 49 3.86e-02 0.171000 5.02e-01
REACTOME SIGNALING BY RETINOIC ACID 41 3.87e-02 0.187000 5.02e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION TERMINATION 30 3.88e-02 0.218000 5.02e-01
REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21 59 3.89e-02 0.155000 5.02e-01
REACTOME DEFECTIVE CHST6 CAUSES MCDC1 8 3.92e-02 -0.421000 5.02e-01
REACTOME ORC1 REMOVAL FROM CHROMATIN 70 3.97e-02 0.142000 5.02e-01
REACTOME WAX AND PLASMALOGEN BIOSYNTHESIS 5 3.98e-02 0.531000 5.02e-01
REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE 10 3.98e-02 0.375000 5.02e-01
REACTOME HIV TRANSCRIPTION INITIATION 43 4.05e-02 0.181000 5.02e-01
REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL 13 4.10e-02 0.327000 5.02e-01
REACTOME FORMATION OF INCISION COMPLEX IN GG NER 40 4.11e-02 0.187000 5.02e-01
REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS 8 4.14e-02 0.416000 5.02e-01
REACTOME DISEASES OF GLYCOSYLATION 137 4.16e-02 -0.101000 5.02e-01
REACTOME SIGNALING BY EGFR IN CANCER 25 4.19e-02 0.235000 5.02e-01
REACTOME COLLAGEN CHAIN TRIMERIZATION 42 4.20e-02 -0.181000 5.02e-01
REACTOME MITOCHONDRIAL BIOGENESIS 87 4.21e-02 0.126000 5.02e-01
REACTOME TRANSPORT OF NUCLEOTIDE SUGARS 8 4.28e-02 0.414000 5.02e-01
REACTOME STABILIZATION OF P53 56 4.32e-02 0.156000 5.02e-01
REACTOME APOPTOTIC EXECUTION PHASE 49 4.32e-02 0.167000 5.02e-01
REACTOME SIGNALING BY ACTIVIN 15 4.33e-02 0.301000 5.02e-01
REACTOME INFECTIOUS DISEASE 910 4.33e-02 0.039500 5.02e-01
REACTOME DISEASES OF IMMUNE SYSTEM 29 4.34e-02 0.217000 5.02e-01
REACTOME DNA REPLICATION PRE INITIATION 150 4.40e-02 0.095300 5.06e-01
REACTOME GRB2 EVENTS IN ERBB2 SIGNALING 16 4.48e-02 0.290000 5.11e-01
REACTOME NEGATIVE REGULATION OF FLT3 15 4.57e-02 0.298000 5.13e-01
REACTOME COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES 65 4.58e-02 -0.143000 5.13e-01
REACTOME MEIOTIC RECOMBINATION 80 4.60e-02 0.129000 5.13e-01
REACTOME CRISTAE FORMATION 27 4.65e-02 0.221000 5.13e-01
REACTOME SIGNALING BY FLT3 FUSION PROTEINS 19 4.68e-02 0.263000 5.13e-01
REACTOME SHC RELATED EVENTS TRIGGERED BY IGF1R 9 4.68e-02 0.383000 5.13e-01
REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS 299 4.73e-02 0.066700 5.13e-01
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION 1356 4.80e-02 0.032000 5.13e-01
REACTOME BIOSYNTHESIS OF MARESINS 8 4.80e-02 -0.404000 5.13e-01
REACTOME ION CHANNEL TRANSPORT 172 4.81e-02 -0.087400 5.13e-01
REACTOME DNA REPLICATION 178 4.84e-02 0.085700 5.13e-01
REACTOME SIGNALING BY ERBB4 57 4.93e-02 0.151000 5.15e-01
REACTOME REGULATION OF RAS BY GAPS 66 4.98e-02 0.140000 5.15e-01
REACTOME COLLAGEN FORMATION 88 4.98e-02 -0.121000 5.15e-01
REACTOME NEDDYLATION 235 5.01e-02 0.074200 5.15e-01
REACTOME ERBB2 ACTIVATES PTK6 SIGNALING 13 5.01e-02 0.314000 5.15e-01
REACTOME HEDGEHOG ON STATE 85 5.11e-02 0.122000 5.21e-01
REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS 86 5.35e-02 0.120000 5.34e-01
REACTOME INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION 21 5.39e-02 -0.243000 5.34e-01
REACTOME METABOLISM OF FAT SOLUBLE VITAMINS 46 5.42e-02 -0.164000 5.34e-01
REACTOME TRANSLATION 278 5.48e-02 0.066900 5.34e-01
REACTOME GPCR LIGAND BINDING 444 5.53e-02 0.053100 5.34e-01
REACTOME SIGNALING BY CSF1 M CSF IN MYELOID CELLS 30 5.69e-02 0.201000 5.34e-01
REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX 13 5.70e-02 0.305000 5.34e-01
REACTOME PARACETAMOL ADME 26 5.73e-02 -0.215000 5.34e-01
REACTOME RESPONSE TO METAL IONS 14 5.74e-02 0.293000 5.34e-01
REACTOME MITOCHONDRIAL PROTEIN IMPORT 58 5.75e-02 0.144000 5.34e-01
REACTOME ACTIVATION OF C3 AND C5 6 5.77e-02 -0.447000 5.34e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS 121 5.79e-02 0.099800 5.34e-01
REACTOME INFLAMMASOMES 21 5.83e-02 0.239000 5.34e-01
REACTOME SIGNALING BY RECEPTOR TYROSINE KINASES 507 5.84e-02 0.049100 5.34e-01
REACTOME DEFECTIVE GALNT3 CAUSES HFTC 16 5.87e-02 -0.273000 5.34e-01
REACTOME KINESINS 59 5.89e-02 -0.142000 5.34e-01
REACTOME ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS 5 5.93e-02 -0.487000 5.34e-01
REACTOME PROSTANOID LIGAND RECEPTORS 9 5.98e-02 0.362000 5.34e-01
REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES 39 6.00e-02 0.174000 5.34e-01
REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX 15 6.01e-02 0.280000 5.34e-01
REACTOME DEUBIQUITINATION 260 6.03e-02 0.067700 5.34e-01
REACTOME SIGNALING BY ERBB2 50 6.04e-02 0.154000 5.34e-01
REACTOME PEPTIDE LIGAND BINDING RECEPTORS 188 6.04e-02 0.079400 5.34e-01
REACTOME AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA 54 6.05e-02 0.148000 5.34e-01
REACTOME FREE FATTY ACID RECEPTORS 5 6.05e-02 0.485000 5.34e-01
REACTOME S PHASE 159 6.09e-02 0.086100 5.34e-01
REACTOME OPSINS 7 6.18e-02 -0.408000 5.34e-01
REACTOME UCH PROTEINASES 99 6.23e-02 0.108000 5.34e-01
REACTOME DEGRADATION OF CYSTEINE AND HOMOCYSTEINE 15 6.24e-02 0.278000 5.34e-01
REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS 39 6.26e-02 -0.172000 5.34e-01
REACTOME RNA POLYMERASE I PROMOTER ESCAPE 83 6.27e-02 0.118000 5.34e-01
REACTOME INTERLEUKIN 12 SIGNALING 43 6.30e-02 0.164000 5.34e-01
REACTOME UPTAKE OF DIETARY COBALAMINS INTO ENTEROCYTES 9 6.33e-02 -0.357000 5.34e-01
REACTOME SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE 91 6.35e-02 0.113000 5.34e-01
REACTOME FORMATION OF THE CORNIFIED ENVELOPE 125 6.39e-02 -0.095900 5.34e-01
REACTOME COPII MEDIATED VESICLE TRANSPORT 66 6.42e-02 0.132000 5.34e-01
REACTOME HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE 43 6.45e-02 0.163000 5.34e-01
REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS 16 6.47e-02 0.267000 5.34e-01
REACTOME SHC MEDIATED CASCADE FGFR1 21 6.51e-02 0.233000 5.34e-01
REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION 10 6.55e-02 0.336000 5.34e-01
REACTOME DNA DOUBLE STRAND BREAK REPAIR 162 6.56e-02 0.083800 5.34e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA 27 6.62e-02 0.204000 5.35e-01
REACTOME CELLULAR SENESCENCE 189 6.70e-02 0.077300 5.37e-01
REACTOME AZATHIOPRINE ADME 22 6.74e-02 -0.225000 5.37e-01
REACTOME SIGNALLING TO ERKS 34 6.78e-02 0.181000 5.37e-01
REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS 53 6.80e-02 0.145000 5.37e-01
REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING 45 6.81e-02 0.157000 5.37e-01
REACTOME INTERLEUKIN 2 FAMILY SIGNALING 40 6.83e-02 0.167000 5.37e-01
REACTOME SHC MEDIATED CASCADE FGFR3 17 6.88e-02 0.255000 5.38e-01
REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION 26 6.92e-02 0.206000 5.39e-01
REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 22 6.96e-02 0.223000 5.39e-01
REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION 35 6.99e-02 0.177000 5.39e-01
REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE 17 7.06e-02 -0.253000 5.40e-01
REACTOME RNA POLYMERASE II PRE TRANSCRIPTION EVENTS 77 7.08e-02 0.119000 5.40e-01
REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY 10 7.21e-02 -0.328000 5.45e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES 33 7.21e-02 0.181000 5.45e-01
REACTOME SYNTHESIS OF DNA 119 7.35e-02 0.095000 5.51e-01
REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION 59 7.38e-02 0.135000 5.51e-01
REACTOME SIGNALING BY FLT3 ITD AND TKD MUTANTS 16 7.39e-02 0.258000 5.51e-01
REACTOME FORMATION OF XYLULOSE 5 PHOSPHATE 5 7.43e-02 0.461000 5.52e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1 229 7.50e-02 0.068300 5.55e-01
REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP 104 7.54e-02 0.101000 5.55e-01
REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION 20 7.67e-02 0.229000 5.59e-01
REACTOME PHENYLALANINE AND TYROSINE METABOLISM 11 7.71e-02 0.308000 5.59e-01
REACTOME MET ACTIVATES RAS SIGNALING 11 7.72e-02 0.308000 5.59e-01
REACTOME GROWTH HORMONE RECEPTOR SIGNALING 24 7.74e-02 -0.208000 5.59e-01
REACTOME CLATHRIN MEDIATED ENDOCYTOSIS 139 7.76e-02 0.086700 5.59e-01
REACTOME RAB REGULATION OF TRAFFICKING 110 7.81e-02 0.097200 5.60e-01
REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES 34 7.88e-02 0.174000 5.63e-01
REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS 18 7.96e-02 0.239000 5.63e-01
REACTOME PI3K EVENTS IN ERBB2 SIGNALING 16 7.98e-02 0.253000 5.63e-01
REACTOME SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS 12 8.02e-02 0.292000 5.63e-01
REACTOME ARACHIDONATE PRODUCTION FROM DAG 5 8.03e-02 -0.452000 5.63e-01
REACTOME SHC MEDIATED CASCADE FGFR4 19 8.22e-02 0.230000 5.66e-01
REACTOME NEF MEDIATED CD8 DOWN REGULATION 7 8.26e-02 -0.379000 5.66e-01
REACTOME CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY 84 8.31e-02 0.109000 5.66e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX2 117 8.40e-02 0.092500 5.66e-01
REACTOME HDR THROUGH HOMOLOGOUS RECOMBINATION HRR 66 8.40e-02 0.123000 5.66e-01
REACTOME REGULATION OF BACH1 ACTIVITY 11 8.42e-02 0.301000 5.66e-01
REACTOME NECTIN NECL TRANS HETERODIMERIZATION 7 8.43e-02 0.377000 5.66e-01
REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS 15 8.44e-02 0.257000 5.66e-01
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION 361 8.44e-02 0.052900 5.66e-01
REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER 77 8.48e-02 0.114000 5.66e-01
REACTOME NCAM1 INTERACTIONS 41 8.49e-02 -0.155000 5.66e-01
REACTOME DISEASES OF METABOLISM 237 8.55e-02 -0.064800 5.66e-01
REACTOME HOMOLOGY DIRECTED REPAIR 132 8.56e-02 0.086700 5.66e-01
REACTOME VASOPRESSIN LIKE RECEPTORS 5 8.63e-02 0.443000 5.66e-01
REACTOME SYNTHESIS OF 15 EICOSATETRAENOIC ACID DERIVATIVES 6 8.64e-02 0.404000 5.66e-01
REACTOME OXIDATIVE STRESS INDUCED SENESCENCE 118 8.67e-02 0.091300 5.66e-01
REACTOME TIE2 SIGNALING 18 8.68e-02 0.233000 5.66e-01
REACTOME PHASE 4 RESTING MEMBRANE POTENTIAL 19 8.69e-02 -0.227000 5.66e-01
REACTOME CREB3 FACTORS ACTIVATE GENES 8 8.79e-02 0.348000 5.69e-01
REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE 35 8.81e-02 0.167000 5.69e-01
REACTOME TRANSPORT OF FATTY ACIDS 8 8.84e-02 -0.348000 5.69e-01
REACTOME RUNX3 REGULATES WNT SIGNALING 8 8.91e-02 -0.347000 5.71e-01
REACTOME SIGNALING BY KIT IN DISEASE 20 8.95e-02 0.219000 5.72e-01
REACTOME REGULATION OF SIGNALING BY NODAL 9 8.98e-02 0.327000 5.72e-01
REACTOME THE NLRP3 INFLAMMASOME 16 9.08e-02 0.244000 5.76e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION 102 9.19e-02 0.096600 5.81e-01
REACTOME METALLOTHIONEINS BIND METALS 11 9.34e-02 0.292000 5.83e-01
REACTOME RAC3 GTPASE CYCLE 85 9.40e-02 0.105000 5.83e-01
REACTOME HUR ELAVL1 BINDS AND STABILIZES MRNA 8 9.40e-02 0.342000 5.83e-01
REACTOME SIGNALING BY FGFR IN DISEASE 62 9.45e-02 0.123000 5.83e-01
REACTOME BINDING OF TCF LEF CTNNB1 TO TARGET GENE PROMOTERS 8 9.56e-02 -0.340000 5.83e-01
REACTOME MEMBRANE TRAFFICKING 603 9.58e-02 0.039700 5.83e-01
REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS 16 9.60e-02 0.240000 5.83e-01
REACTOME INTERLEUKIN 36 PATHWAY 7 9.61e-02 -0.363000 5.83e-01
REACTOME CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS 100 9.61e-02 0.096300 5.83e-01
REACTOME BH3 ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI APOPTOTIC BCL 2 MEMBERS 9 9.63e-02 0.320000 5.83e-01
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA 263 9.65e-02 0.059500 5.83e-01
REACTOME NEGATIVE REGULATION OF NOTCH4 SIGNALING 53 9.66e-02 0.132000 5.83e-01
REACTOME SIGNALING BY ROBO RECEPTORS 206 9.69e-02 0.067100 5.83e-01
REACTOME EICOSANOID LIGAND BINDING RECEPTORS 14 9.76e-02 0.256000 5.83e-01
REACTOME SMOOTH MUSCLE CONTRACTION 43 9.76e-02 -0.146000 5.83e-01
REACTOME VITAMIN C ASCORBATE METABOLISM 8 9.81e-02 0.338000 5.83e-01
REACTOME MET PROMOTES CELL MOTILITY 41 9.95e-02 -0.149000 5.86e-01
REACTOME CROSSLINKING OF COLLAGEN FIBRILS 16 9.98e-02 -0.238000 5.86e-01
REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING 26 9.99e-02 0.186000 5.86e-01
REACTOME DISEASES OF DNA REPAIR 51 1.00e-01 0.133000 5.86e-01
REACTOME ANCHORING FIBRIL FORMATION 13 1.01e-01 -0.263000 5.86e-01
REACTOME PROTEIN LOCALIZATION 153 1.01e-01 0.076800 5.86e-01
REACTOME DEGRADATION OF GLI1 BY THE PROTEASOME 59 1.01e-01 0.123000 5.86e-01
REACTOME LDL REMODELING 6 1.01e-01 0.386000 5.86e-01
REACTOME STAT5 ACTIVATION 7 1.02e-01 0.357000 5.88e-01
REACTOME DNA REPAIR 321 1.03e-01 0.052900 5.92e-01
REACTOME DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING 61 1.04e-01 0.120000 5.92e-01
REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY 51 1.04e-01 0.132000 5.92e-01
REACTOME O LINKED GLYCOSYLATION 109 1.04e-01 -0.090100 5.92e-01
REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE 109 1.05e-01 0.089900 5.94e-01
REACTOME SIGNALING BY ERBB2 IN CANCER 26 1.07e-01 0.183000 6.00e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION 45 1.07e-01 0.139000 6.00e-01
REACTOME PROCESSING OF DNA DOUBLE STRAND BREAK ENDS 93 1.08e-01 0.096500 6.00e-01
REACTOME HDR THROUGH SINGLE STRAND ANNEALING SSA 37 1.08e-01 0.153000 6.00e-01
REACTOME PEPTIDE HORMONE BIOSYNTHESIS 13 1.08e-01 0.257000 6.00e-01
REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL 129 1.08e-01 0.081900 6.00e-01
REACTOME ANTIGEN PROCESSING CROSS PRESENTATION 98 1.09e-01 0.093800 6.00e-01
REACTOME CELL CYCLE MITOTIC 539 1.09e-01 0.040300 6.02e-01
REACTOME RHO GTPASES ACTIVATE NADPH OXIDASES 21 1.10e-01 0.202000 6.02e-01
REACTOME GOLGI TO ER RETROGRADE TRANSPORT 132 1.11e-01 -0.080400 6.05e-01
REACTOME REGULATION OF RUNX3 EXPRESSION AND ACTIVITY 54 1.11e-01 0.125000 6.05e-01
REACTOME SULFUR AMINO ACID METABOLISM 27 1.11e-01 0.177000 6.05e-01
REACTOME DNA DOUBLE STRAND BREAK RESPONSE 74 1.12e-01 0.107000 6.07e-01
REACTOME ACYL CHAIN REMODELLING OF PE 29 1.13e-01 -0.170000 6.08e-01
REACTOME TRANSPORT OF SMALL MOLECULES 697 1.13e-01 -0.035200 6.08e-01
REACTOME ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION 16 1.13e-01 0.229000 6.08e-01
REACTOME NRAGE SIGNALS DEATH THROUGH JNK 53 1.14e-01 -0.125000 6.09e-01
REACTOME DEVELOPMENTAL BIOLOGY 1115 1.14e-01 0.028000 6.09e-01
REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH 62 1.15e-01 -0.116000 6.09e-01
REACTOME REGULATION OF PTEN GENE TRANSCRIPTION 59 1.15e-01 0.119000 6.11e-01
REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE 277 1.16e-01 0.054800 6.13e-01
REACTOME OPIOID SIGNALLING 89 1.17e-01 0.096200 6.13e-01
REACTOME MEIOSIS 110 1.17e-01 0.086500 6.13e-01
REACTOME GASTRULATION 49 1.18e-01 0.129000 6.18e-01
REACTOME PTEN REGULATION 135 1.19e-01 0.077700 6.22e-01
REACTOME TACHYKININ RECEPTORS BIND TACHYKININS 5 1.20e-01 0.402000 6.22e-01
REACTOME DISEASES ASSOCIATED WITH SURFACTANT METABOLISM 9 1.20e-01 -0.299000 6.22e-01
REACTOME ERBB2 REGULATES CELL MOTILITY 15 1.21e-01 0.231000 6.22e-01
REACTOME REGULATION OF KIT SIGNALING 16 1.22e-01 0.223000 6.22e-01
REACTOME MTORC1 MEDIATED SIGNALLING 23 1.22e-01 0.186000 6.22e-01
REACTOME TRIF MEDIATED PROGRAMMED CELL DEATH 9 1.22e-01 0.298000 6.22e-01
REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION 13 1.23e-01 0.247000 6.22e-01
REACTOME ASPARAGINE N LINKED GLYCOSYLATION 299 1.23e-01 0.051800 6.22e-01
REACTOME SIGNALING BY CSF3 G CSF 30 1.23e-01 0.163000 6.22e-01
REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS 35 1.23e-01 0.151000 6.22e-01
REACTOME EGFR INTERACTS WITH PHOSPHOLIPASE C GAMMA 9 1.23e-01 0.297000 6.22e-01
REACTOME GP1B IX V ACTIVATION SIGNALLING 11 1.24e-01 0.268000 6.22e-01
REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 73 1.25e-01 0.104000 6.26e-01
REACTOME DOWNSTREAM SIGNAL TRANSDUCTION 29 1.25e-01 0.164000 6.26e-01
REACTOME SARS COV 1 HOST INTERACTIONS 92 1.26e-01 0.092300 6.26e-01
REACTOME ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES 59 1.30e-01 -0.114000 6.44e-01
REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS 81 1.31e-01 0.096900 6.50e-01
REACTOME SARS COV INFECTIONS 392 1.32e-01 0.044300 6.50e-01
REACTOME STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS 10 1.33e-01 0.275000 6.51e-01
REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 98 1.34e-01 0.087700 6.53e-01
REACTOME CELLULAR RESPONSE TO HYPOXIA 74 1.34e-01 0.101000 6.53e-01
REACTOME DARPP 32 EVENTS 24 1.35e-01 0.176000 6.53e-01
REACTOME BIOLOGICAL OXIDATIONS 210 1.36e-01 -0.059700 6.53e-01
REACTOME PERK REGULATES GENE EXPRESSION 31 1.36e-01 0.155000 6.53e-01
REACTOME PTK6 PROMOTES HIF1A STABILIZATION 6 1.36e-01 0.351000 6.53e-01
REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS 16 1.37e-01 -0.215000 6.53e-01
REACTOME RHO GTPASES ACTIVATE PAKS 19 1.37e-01 -0.197000 6.53e-01
REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION 8 1.37e-01 -0.304000 6.53e-01
REACTOME L1CAM INTERACTIONS 112 1.37e-01 -0.081300 6.53e-01
REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION 23 1.38e-01 -0.179000 6.53e-01
REACTOME MODULATION BY MTB OF HOST IMMUNE SYSTEM 6 1.38e-01 0.350000 6.53e-01
REACTOME MUSCLE CONTRACTION 197 1.38e-01 -0.061300 6.53e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX IN CANCER 8 1.38e-01 0.302000 6.53e-01
REACTOME GLUTAMATE AND GLUTAMINE METABOLISM 13 1.39e-01 0.237000 6.53e-01
REACTOME PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1 9 1.40e-01 0.284000 6.53e-01
REACTOME DEATH RECEPTOR SIGNALING 143 1.42e-01 -0.071200 6.53e-01
REACTOME PLATELET AGGREGATION PLUG FORMATION 39 1.42e-01 0.136000 6.53e-01
REACTOME FORMATION OF LATERAL PLATE MESODERM 5 1.42e-01 0.379000 6.53e-01
REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION 13 1.43e-01 -0.235000 6.53e-01
REACTOME SIGNALING BY NTRKS 132 1.43e-01 0.073800 6.53e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES 61 1.43e-01 0.108000 6.53e-01
REACTOME LOSS OF FUNCTION OF SMAD2 3 IN CANCER 7 1.44e-01 0.319000 6.53e-01
REACTOME LYSOSPHINGOLIPID AND LPA RECEPTORS 14 1.44e-01 0.226000 6.53e-01
REACTOME SARS COV 2 INFECTION 281 1.44e-01 0.050700 6.53e-01
REACTOME TRANSCRIPTION OF THE HIV GENOME 66 1.44e-01 0.104000 6.53e-01
REACTOME GAP JUNCTION ASSEMBLY 36 1.44e-01 -0.141000 6.53e-01
REACTOME AMYLOID FIBER FORMATION 102 1.44e-01 0.083600 6.53e-01
REACTOME LGI ADAM INTERACTIONS 14 1.44e-01 0.225000 6.53e-01
REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS 6 1.45e-01 -0.343000 6.55e-01
REACTOME SIGNAL AMPLIFICATION 33 1.46e-01 0.146000 6.56e-01
REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN 37 1.46e-01 0.138000 6.56e-01
REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS 113 1.47e-01 0.079100 6.56e-01
REACTOME RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK 47 1.47e-01 0.122000 6.56e-01
REACTOME EGFR DOWNREGULATION 30 1.47e-01 0.153000 6.56e-01
REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE 11 1.48e-01 -0.252000 6.56e-01
REACTOME HIV INFECTION 223 1.50e-01 0.056000 6.56e-01
REACTOME RAB GERANYLGERANYLATION 57 1.50e-01 0.110000 6.56e-01
REACTOME SIGNALING BY NODAL 20 1.50e-01 0.186000 6.56e-01
REACTOME SIGNALING BY INSULIN RECEPTOR 80 1.51e-01 0.092900 6.56e-01
REACTOME ZINC TRANSPORTERS 15 1.51e-01 0.214000 6.56e-01
REACTOME INTEGRIN SIGNALING 27 1.51e-01 0.160000 6.56e-01
REACTOME EPITHELIAL MESENCHYMAL TRANSITION EMT DURING GASTRULATION 7 1.51e-01 0.313000 6.56e-01
REACTOME SENSING OF DNA DOUBLE STRAND BREAKS 6 1.51e-01 0.338000 6.56e-01
REACTOME SYNTHESIS OF PIPS AT THE ER MEMBRANE 5 1.51e-01 -0.370000 6.56e-01
REACTOME RETINOID CYCLE DISEASE EVENTS 11 1.53e-01 -0.249000 6.59e-01
REACTOME LATE SARS COV 2 INFECTION EVENTS 67 1.53e-01 0.101000 6.59e-01
REACTOME FORMATION OF AXIAL MESODERM 14 1.54e-01 0.220000 6.60e-01
REACTOME APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS 87 1.55e-01 0.088300 6.63e-01
REACTOME NUCLEOTIDE CATABOLISM 35 1.55e-01 0.139000 6.64e-01
REACTOME TOLL LIKE RECEPTOR 9 TLR9 CASCADE 100 1.56e-01 0.082100 6.64e-01
REACTOME METABOLISM OF CARBOHYDRATES 279 1.57e-01 0.049200 6.64e-01
REACTOME HEMOSTASIS 591 1.57e-01 0.034000 6.64e-01
REACTOME ATTACHMENT OF GPI ANCHOR TO UPAR 7 1.58e-01 0.308000 6.64e-01
REACTOME SIGNALLING TO RAS 20 1.58e-01 0.182000 6.64e-01
REACTOME P38MAPK EVENTS 13 1.58e-01 0.226000 6.64e-01
REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION 16 1.58e-01 0.204000 6.64e-01
REACTOME ACTIVATION OF BH3 ONLY PROTEINS 30 1.59e-01 0.149000 6.64e-01
REACTOME INTERLEUKIN 1 PROCESSING 9 1.60e-01 0.271000 6.64e-01
REACTOME TYROSINE CATABOLISM 5 1.60e-01 0.363000 6.64e-01
REACTOME TRAIL SIGNALING 8 1.60e-01 0.287000 6.64e-01
REACTOME HDACS DEACETYLATE HISTONES 85 1.60e-01 0.088100 6.64e-01
REACTOME G ALPHA 12 13 SIGNALLING EVENTS 74 1.63e-01 -0.093900 6.69e-01
REACTOME NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 24 1.63e-01 -0.164000 6.69e-01
REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS 11 1.64e-01 -0.243000 6.69e-01
REACTOME REGULATION OF SIGNALING BY CBL 22 1.64e-01 0.171000 6.69e-01
REACTOME SIGNALING BY NUCLEAR RECEPTORS 283 1.64e-01 0.048100 6.69e-01
REACTOME HEDGEHOG LIGAND BIOGENESIS 64 1.65e-01 0.100000 6.69e-01
REACTOME REPRODUCTION 136 1.65e-01 0.069000 6.69e-01
REACTOME PROLACTIN RECEPTOR SIGNALING 15 1.65e-01 -0.207000 6.69e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS 5 1.65e-01 0.359000 6.69e-01
REACTOME MET RECEPTOR RECYCLING 10 1.66e-01 0.253000 6.70e-01
REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX 57 1.66e-01 0.106000 6.70e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS 8 1.67e-01 0.282000 6.72e-01
REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS 60 1.68e-01 0.103000 6.73e-01
REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER 81 1.71e-01 0.088000 6.83e-01
REACTOME CDC42 GTPASE CYCLE 144 1.71e-01 -0.066100 6.83e-01
REACTOME MAPK FAMILY SIGNALING CASCADES 314 1.72e-01 0.044800 6.84e-01
REACTOME SIGNALING BY ALK IN CANCER 53 1.72e-01 0.108000 6.84e-01
REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION 160 1.73e-01 -0.062500 6.84e-01
REACTOME MITOTIC G2 G2 M PHASES 194 1.73e-01 0.056700 6.84e-01
REACTOME CLEC7A DECTIN 1 SIGNALING 97 1.73e-01 0.080000 6.84e-01
REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS 63 1.74e-01 0.099100 6.84e-01
REACTOME ASSEMBLY OF THE HIV VIRION 16 1.74e-01 0.196000 6.84e-01
REACTOME GRB7 EVENTS IN ERBB2 SIGNALING 5 1.75e-01 0.350000 6.84e-01
REACTOME SIGNALING BY FGFR2 IN DISEASE 42 1.76e-01 0.121000 6.84e-01
REACTOME INFLUENZA INFECTION 149 1.76e-01 0.064200 6.84e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3 11 1.76e-01 0.235000 6.84e-01
REACTOME FGFRL1 MODULATION OF FGFR1 SIGNALING 13 1.76e-01 0.217000 6.84e-01
REACTOME MITOCHONDRIAL TRANSLATION 93 1.77e-01 0.081000 6.84e-01
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION 138 1.77e-01 0.066500 6.84e-01
REACTOME SYNTHESIS OF 12 EICOSATETRAENOIC ACID DERIVATIVES 7 1.77e-01 0.294000 6.84e-01
REACTOME FLT3 SIGNALING THROUGH SRC FAMILY KINASES 6 1.78e-01 0.317000 6.86e-01
REACTOME FLT3 SIGNALING BY CBL MUTANTS 7 1.80e-01 0.293000 6.86e-01
REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS 12 1.80e-01 0.223000 6.86e-01
REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS 111 1.81e-01 0.073600 6.86e-01
REACTOME TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT 18 1.81e-01 0.182000 6.86e-01
REACTOME REGULATION OF BETA CELL DEVELOPMENT 41 1.81e-01 0.121000 6.86e-01
REACTOME G ALPHA Q SIGNALLING EVENTS 206 1.83e-01 0.053900 6.86e-01
REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS 8 1.83e-01 -0.272000 6.86e-01
REACTOME O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS 38 1.83e-01 -0.125000 6.86e-01
REACTOME VESICLE MEDIATED TRANSPORT 642 1.83e-01 0.030800 6.86e-01
REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES 353 1.84e-01 0.041200 6.86e-01
REACTOME G PROTEIN ACTIVATION 24 1.84e-01 0.157000 6.86e-01
REACTOME SODIUM COUPLED PHOSPHATE COTRANSPORTERS 5 1.84e-01 -0.343000 6.86e-01
REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS 15 1.84e-01 -0.198000 6.86e-01
REACTOME SIGNALING BY FGFR2 72 1.84e-01 0.090500 6.87e-01
REACTOME TP53 REGULATES METABOLIC GENES 81 1.85e-01 0.085200 6.87e-01
REACTOME SEROTONIN NEUROTRANSMITTER RELEASE CYCLE 17 1.85e-01 -0.186000 6.87e-01
REACTOME TBC RABGAPS 40 1.86e-01 0.121000 6.87e-01
REACTOME DUAL INCISION IN GG NER 39 1.86e-01 0.122000 6.87e-01
REACTOME INDUCTION OF CELL CELL FUSION 12 1.87e-01 -0.220000 6.88e-01
REACTOME PI3K EVENTS IN ERBB4 SIGNALING 10 1.87e-01 0.241000 6.88e-01
REACTOME SYNTHESIS OF PC 27 1.88e-01 0.146000 6.89e-01
REACTOME RMTS METHYLATE HISTONE ARGININES 72 1.89e-01 0.089600 6.89e-01
REACTOME FRS MEDIATED FGFR1 SIGNALING 23 1.89e-01 0.158000 6.89e-01
REACTOME MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS 13 1.90e-01 0.210000 6.89e-01
REACTOME HIV LIFE CYCLE 145 1.90e-01 0.063100 6.89e-01
REACTOME NEGATIVE REGULATION OF MET ACTIVITY 20 1.90e-01 0.169000 6.90e-01
REACTOME RET SIGNALING 40 1.91e-01 0.119000 6.92e-01
REACTOME G ALPHA I SIGNALLING EVENTS 304 1.92e-01 0.043500 6.92e-01
REACTOME TRNA PROCESSING IN THE NUCLEUS 58 1.93e-01 -0.098700 6.97e-01
REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT 159 1.94e-01 0.059700 6.97e-01
REACTOME SPHINGOLIPID METABOLISM 84 1.96e-01 0.081700 6.98e-01
REACTOME INTERLEUKIN 18 SIGNALING 8 1.96e-01 -0.264000 6.98e-01
REACTOME NONHOMOLOGOUS END JOINING NHEJ 64 1.96e-01 0.093400 6.98e-01
REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION 296 1.97e-01 0.043600 6.98e-01
REACTOME GENERATION OF SECOND MESSENGER MOLECULES 30 1.97e-01 -0.136000 6.98e-01
REACTOME SIGNALING BY HEDGEHOG 148 1.97e-01 0.061400 6.98e-01
REACTOME EUKARYOTIC TRANSLATION INITIATION 110 1.97e-01 0.071100 6.98e-01
REACTOME BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS 10 1.98e-01 -0.235000 6.98e-01
REACTOME TLR3 MEDIATED TICAM1 DEPENDENT PROGRAMMED CELL DEATH 6 1.98e-01 0.303000 6.99e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS 5 2.01e-01 0.330000 7.03e-01
REACTOME LTC4 CYSLTR MEDIATED IL4 PRODUCTION 6 2.01e-01 -0.301000 7.03e-01
REACTOME CALCITONIN LIKE LIGAND RECEPTORS 10 2.01e-01 0.233000 7.03e-01
REACTOME RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES 16 2.02e-01 -0.184000 7.03e-01
REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION 84 2.02e-01 0.080600 7.03e-01
REACTOME TNFR2 NON CANONICAL NF KB PATHWAY 96 2.03e-01 0.075200 7.05e-01
REACTOME IRE1ALPHA ACTIVATES CHAPERONES 48 2.04e-01 0.106000 7.05e-01
REACTOME SIGNALING BY NOTCH4 80 2.04e-01 0.082100 7.05e-01
REACTOME TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX 10 2.05e-01 0.232000 7.05e-01
REACTOME XENOBIOTICS 22 2.07e-01 -0.156000 7.05e-01
REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION 11 2.07e-01 0.220000 7.05e-01
REACTOME EGFR TRANSACTIVATION BY GASTRIN 9 2.07e-01 0.243000 7.05e-01
REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY 14 2.08e-01 -0.194000 7.05e-01
REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES 14 2.08e-01 0.194000 7.05e-01
REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS 28 2.09e-01 0.137000 7.05e-01
REACTOME STIMULI SENSING CHANNELS 100 2.09e-01 -0.072700 7.05e-01
REACTOME SIGNALING BY MST1 5 2.09e-01 0.325000 7.05e-01
REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS 100 2.09e-01 0.072700 7.05e-01
REACTOME CALNEXIN CALRETICULIN CYCLE 26 2.10e-01 0.142000 7.05e-01
REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING 89 2.10e-01 -0.076900 7.05e-01
REACTOME ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY 10 2.10e-01 0.229000 7.05e-01
REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 19 2.11e-01 0.166000 7.05e-01
REACTOME RIPK1 MEDIATED REGULATED NECROSIS 30 2.12e-01 0.132000 7.05e-01
REACTOME ASPARTATE AND ASPARAGINE METABOLISM 11 2.12e-01 0.218000 7.05e-01
REACTOME PEPTIDE HORMONE METABOLISM 84 2.12e-01 0.078800 7.05e-01
REACTOME RNA POLYMERASE II TRANSCRIBES SNRNA GENES 77 2.13e-01 0.082200 7.05e-01
REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 54 2.13e-01 0.098000 7.05e-01
REACTOME IKBA VARIANT LEADS TO EDA ID 6 2.13e-01 -0.294000 7.05e-01
REACTOME COLLAGEN DEGRADATION 61 2.13e-01 -0.092100 7.05e-01
REACTOME COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING 38 2.14e-01 0.117000 7.05e-01
REACTOME PKA ACTIVATION IN GLUCAGON SIGNALLING 17 2.14e-01 -0.174000 7.05e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES 8 2.15e-01 0.253000 7.05e-01
REACTOME SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL 8 2.15e-01 -0.253000 7.05e-01
REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III 31 2.16e-01 -0.128000 7.05e-01
REACTOME NEUREXINS AND NEUROLIGINS 51 2.16e-01 0.100000 7.05e-01
REACTOME HDL REMODELING 10 2.16e-01 0.226000 7.05e-01
REACTOME COMPLEMENT CASCADE 54 2.16e-01 -0.097300 7.05e-01
REACTOME CARNITINE METABOLISM 13 2.16e-01 0.198000 7.05e-01
REACTOME COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC 52 2.18e-01 -0.098800 7.08e-01
REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R 52 2.18e-01 0.098700 7.08e-01
REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY 26 2.19e-01 -0.139000 7.08e-01
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S 53 2.19e-01 0.097600 7.08e-01
REACTOME EPHRIN SIGNALING 17 2.20e-01 -0.172000 7.08e-01
REACTOME FRS MEDIATED FGFR3 SIGNALING 19 2.20e-01 0.162000 7.08e-01
REACTOME GLUCURONIDATION 23 2.21e-01 -0.148000 7.08e-01
REACTOME DEGRADATION OF DVL 56 2.21e-01 0.094600 7.08e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES 29 2.21e-01 0.131000 7.08e-01
REACTOME GAP JUNCTION TRAFFICKING AND REGULATION 49 2.22e-01 -0.101000 7.08e-01
REACTOME SIGNALING BY LEPTIN 11 2.23e-01 -0.212000 7.12e-01
REACTOME CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2 11 2.24e-01 0.212000 7.13e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES 12 2.25e-01 0.202000 7.14e-01
REACTOME TRAF6 MEDIATED NF KB ACTIVATION 24 2.25e-01 0.143000 7.14e-01
REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS 11 2.26e-01 -0.211000 7.15e-01
REACTOME HS GAG DEGRADATION 19 2.27e-01 -0.160000 7.17e-01
REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON 17 2.28e-01 0.169000 7.19e-01
REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY 23 2.29e-01 -0.145000 7.21e-01
REACTOME SARS COV 2 HOST INTERACTIONS 191 2.30e-01 0.050300 7.22e-01
REACTOME DAP12 SIGNALING 27 2.30e-01 0.133000 7.22e-01
REACTOME RUNX3 REGULATES NOTCH SIGNALING 13 2.32e-01 -0.191000 7.22e-01
REACTOME DEFECTIVE CHSY1 CAUSES TPBS 7 2.32e-01 0.261000 7.22e-01
REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE 63 2.33e-01 -0.087000 7.22e-01
REACTOME THE ACTIVATION OF ARYLSULFATASES 8 2.33e-01 0.243000 7.22e-01
REACTOME SELENOAMINO ACID METABOLISM 108 2.33e-01 0.066400 7.22e-01
REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS 101 2.33e-01 -0.068600 7.22e-01
REACTOME MRNA CAPPING 28 2.33e-01 0.130000 7.22e-01
REACTOME TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE 10 2.34e-01 -0.217000 7.24e-01
REACTOME COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC 98 2.36e-01 -0.069200 7.26e-01
REACTOME REGULATION OF TP53 EXPRESSION AND DEGRADATION 37 2.37e-01 0.112000 7.26e-01
REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX 8 2.37e-01 0.242000 7.26e-01
REACTOME FRS MEDIATED FGFR4 SIGNALING 21 2.37e-01 0.149000 7.26e-01
REACTOME COMMON PATHWAY OF FIBRIN CLOT FORMATION 21 2.38e-01 -0.149000 7.26e-01
REACTOME SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX 15 2.38e-01 -0.176000 7.26e-01
REACTOME DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15 8 2.38e-01 -0.241000 7.26e-01
REACTOME RHOBTB3 ATPASE CYCLE 8 2.40e-01 -0.240000 7.29e-01
REACTOME NUCLEOTIDE EXCISION REPAIR 107 2.40e-01 0.065700 7.29e-01
REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK 111 2.41e-01 0.064500 7.29e-01
REACTOME MET ACTIVATES RAP1 AND RAC1 11 2.41e-01 0.204000 7.29e-01
REACTOME CLEC7A INFLAMMASOME PATHWAY 6 2.42e-01 0.276000 7.29e-01
REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING 6 2.43e-01 0.275000 7.30e-01
REACTOME SUMOYLATION 179 2.44e-01 0.050500 7.30e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1 16 2.44e-01 0.168000 7.30e-01
REACTOME INSULIN RECEPTOR RECYCLING 29 2.44e-01 0.125000 7.30e-01
REACTOME HORMONE LIGAND BINDING RECEPTORS 12 2.44e-01 -0.194000 7.30e-01
REACTOME SIGNALING BY GPCR 673 2.45e-01 0.026300 7.30e-01
REACTOME FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS 8 2.46e-01 0.237000 7.30e-01
REACTOME VEGFR2 MEDIATED CELL PROLIFERATION 19 2.46e-01 0.154000 7.30e-01
REACTOME SIGNALING BY THE B CELL RECEPTOR BCR 106 2.46e-01 0.065200 7.30e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR3 24 2.47e-01 0.136000 7.30e-01
REACTOME ORGANIC ANION TRANSPORTERS 10 2.48e-01 0.211000 7.30e-01
REACTOME AMINE LIGAND BINDING RECEPTORS 40 2.48e-01 0.106000 7.30e-01
REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING 16 2.49e-01 0.167000 7.30e-01
REACTOME GLYCOGEN METABOLISM 22 2.49e-01 0.142000 7.30e-01
REACTOME RSK ACTIVATION 5 2.50e-01 -0.297000 7.30e-01
REACTOME SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA 52 2.50e-01 -0.092200 7.30e-01
REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS 9 2.50e-01 -0.221000 7.30e-01
REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION 62 2.50e-01 0.084500 7.30e-01
REACTOME DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS 25 2.51e-01 -0.133000 7.32e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1 31 2.52e-01 0.119000 7.35e-01
REACTOME PRC2 METHYLATES HISTONES AND DNA 65 2.53e-01 0.082000 7.35e-01
REACTOME RAS SIGNALING DOWNSTREAM OF NF1 LOSS OF FUNCTION VARIANTS 7 2.54e-01 0.249000 7.35e-01
REACTOME VITAMINS 6 2.54e-01 0.269000 7.35e-01
REACTOME SIGNALING BY NOTCH3 48 2.54e-01 -0.095100 7.35e-01
REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION 68 2.56e-01 0.079700 7.38e-01
REACTOME CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS 19 2.58e-01 0.150000 7.40e-01
REACTOME DOWNREGULATION OF ERBB4 SIGNALING 9 2.59e-01 0.217000 7.40e-01
REACTOME CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN 45 2.59e-01 -0.097200 7.40e-01
REACTOME ELASTIC FIBRE FORMATION 44 2.60e-01 -0.098200 7.40e-01
REACTOME MRNA SPLICING 197 2.60e-01 0.046500 7.40e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR4 26 2.60e-01 0.128000 7.40e-01
REACTOME ACTIVATION OF MATRIX METALLOPROTEINASES 30 2.60e-01 -0.119000 7.40e-01
REACTOME EXTRA NUCLEAR ESTROGEN SIGNALING 74 2.61e-01 0.075600 7.40e-01
REACTOME G2 PHASE 5 2.61e-01 0.290000 7.40e-01
REACTOME MELANIN BIOSYNTHESIS 5 2.61e-01 -0.290000 7.40e-01
REACTOME SARS COV 2 TARGETS PDZ PROTEINS IN CELL CELL JUNCTION 5 2.61e-01 0.290000 7.40e-01
REACTOME ACYL CHAIN REMODELING OF DAG AND TAG 5 2.64e-01 0.289000 7.46e-01
REACTOME TRANSCRIPTIONAL REGULATION BY MECP2 60 2.65e-01 0.083200 7.47e-01
REACTOME SIGNALING BY NOTCH1 T 7 9 NOTCH1 M1580 K2555 TRANSLOCATION MUTANT 7 2.66e-01 -0.243000 7.48e-01
REACTOME SEMA3A PAK DEPENDENT AXON REPULSION 14 2.67e-01 -0.171000 7.48e-01
REACTOME NONSENSE MEDIATED DECAY NMD 107 2.67e-01 0.062100 7.48e-01
REACTOME PHENYLALANINE METABOLISM 6 2.67e-01 0.262000 7.48e-01
REACTOME RIBAVIRIN ADME 11 2.68e-01 0.193000 7.50e-01
REACTOME HYALURONAN METABOLISM 17 2.69e-01 0.155000 7.50e-01
REACTOME ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA 15 2.69e-01 0.165000 7.50e-01
REACTOME TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION 5 2.69e-01 0.285000 7.50e-01
REACTOME DEFECTIVE CSF2RB CAUSES SMDP5 7 2.72e-01 -0.240000 7.54e-01
REACTOME DOWNREGULATION OF ERBB2 SIGNALING 29 2.73e-01 0.118000 7.54e-01
REACTOME C TYPE LECTIN RECEPTORS CLRS 136 2.73e-01 0.054500 7.54e-01
REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR 24 2.73e-01 0.129000 7.54e-01
REACTOME VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS 42 2.73e-01 -0.097700 7.54e-01
REACTOME COHESIN LOADING ONTO CHROMATIN 8 2.75e-01 -0.223000 7.59e-01
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES 55 2.76e-01 0.084800 7.60e-01
REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 100 2.79e-01 0.062700 7.61e-01
REACTOME TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY 30 2.79e-01 -0.114000 7.61e-01
REACTOME SYNDECAN INTERACTIONS 26 2.79e-01 -0.123000 7.61e-01
REACTOME RUNX3 REGULATES YAP1 MEDIATED TRANSCRIPTION 8 2.80e-01 -0.220000 7.61e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX3 94 2.81e-01 0.064400 7.61e-01
REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS 23 2.81e-01 0.130000 7.61e-01
REACTOME FORMATION OF TC NER PRE INCISION COMPLEX 51 2.81e-01 0.087300 7.61e-01
REACTOME DEGRADATION OF AXIN 54 2.81e-01 0.084800 7.61e-01
REACTOME INTEGRIN CELL SURFACE INTERACTIONS 83 2.82e-01 -0.068300 7.61e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS 9 2.82e-01 -0.207000 7.61e-01
REACTOME INTRINSIC PATHWAY FOR APOPTOSIS 54 2.82e-01 0.084600 7.61e-01
REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B 24 2.83e-01 0.127000 7.61e-01
REACTOME FATTY ACYL COA BIOSYNTHESIS 36 2.83e-01 0.103000 7.61e-01
REACTOME HYALURONAN UPTAKE AND DEGRADATION 12 2.83e-01 0.179000 7.61e-01
REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE 63 2.84e-01 0.078100 7.61e-01
REACTOME GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION 7 2.84e-01 -0.234000 7.61e-01
REACTOME SEROTONIN RECEPTORS 11 2.84e-01 0.186000 7.61e-01
REACTOME ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS 27 2.85e-01 0.119000 7.61e-01
REACTOME MATURATION OF SARS COV 1 SPIKE PROTEIN 5 2.86e-01 0.276000 7.61e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH PI3K 7 2.86e-01 0.233000 7.62e-01
REACTOME ANDROGEN BIOSYNTHESIS 11 2.88e-01 -0.185000 7.64e-01
REACTOME PHOSPHOLIPID METABOLISM 201 2.88e-01 0.043500 7.64e-01
REACTOME VEGF LIGAND RECEPTOR INTERACTIONS 7 2.90e-01 0.231000 7.65e-01
REACTOME CHROMOSOME MAINTENANCE 130 2.90e-01 0.053700 7.65e-01
REACTOME CELLULAR RESPONSE TO STARVATION 147 2.92e-01 0.050400 7.65e-01
REACTOME CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND 16 2.93e-01 0.152000 7.65e-01
REACTOME CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY 12 2.94e-01 -0.175000 7.65e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1 25 2.94e-01 0.121000 7.65e-01
REACTOME CHOLESTEROL BIOSYNTHESIS 25 2.94e-01 -0.121000 7.65e-01
REACTOME RESPIRATORY ELECTRON TRANSPORT 90 2.94e-01 0.064000 7.65e-01
REACTOME DUAL INCISION IN TC NER 63 2.95e-01 0.076400 7.65e-01
REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE 15 2.95e-01 0.156000 7.65e-01
REACTOME SULFIDE OXIDATION TO SULFATE 6 2.96e-01 0.247000 7.65e-01
REACTOME SURFACTANT METABOLISM 28 2.96e-01 -0.114000 7.65e-01
REACTOME RHOBTB2 GTPASE CYCLE 22 2.96e-01 0.129000 7.65e-01
REACTOME NUCLEOTIDE BIOSYNTHESIS 14 2.96e-01 -0.161000 7.65e-01
REACTOME SUPPRESSION OF APOPTOSIS 7 2.97e-01 -0.228000 7.65e-01
REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION 32 2.97e-01 0.107000 7.65e-01
REACTOME TRYPTOPHAN CATABOLISM 14 2.97e-01 -0.161000 7.65e-01
REACTOME LONG TERM POTENTIATION 22 2.97e-01 0.128000 7.65e-01
REACTOME MITOTIC TELOPHASE CYTOKINESIS 11 2.98e-01 -0.181000 7.65e-01
REACTOME FOXO MEDIATED TRANSCRIPTION 65 2.98e-01 0.074700 7.65e-01
REACTOME CHYLOMICRON REMODELING 10 2.99e-01 -0.190000 7.65e-01
REACTOME REGULATED NECROSIS 57 2.99e-01 0.079400 7.65e-01
REACTOME REGULATION OF IFNA IFNB SIGNALING 23 3.00e-01 -0.125000 7.65e-01
REACTOME FBXW7 MUTANTS AND NOTCH1 IN CANCER 5 3.00e-01 0.268000 7.65e-01
REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES 29 3.01e-01 -0.111000 7.65e-01
REACTOME INTESTINAL ABSORPTION 5 3.01e-01 -0.267000 7.65e-01
REACTOME CS DS DEGRADATION 12 3.01e-01 0.172000 7.65e-01
REACTOME PTK6 EXPRESSION 5 3.02e-01 0.267000 7.65e-01
REACTOME ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING 23 3.02e-01 0.124000 7.65e-01
REACTOME NONCANONICAL ACTIVATION OF NOTCH3 8 3.03e-01 0.210000 7.66e-01
REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3 59 3.04e-01 0.077400 7.67e-01
REACTOME ATTACHMENT AND ENTRY 16 3.04e-01 -0.148000 7.67e-01
REACTOME GERM LAYER FORMATION AT GASTRULATION 17 3.05e-01 0.144000 7.69e-01
REACTOME HEME BIOSYNTHESIS 13 3.06e-01 0.164000 7.70e-01
REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE 21 3.08e-01 -0.129000 7.72e-01
REACTOME N GLYCAN ANTENNAE ELONGATION 15 3.08e-01 0.152000 7.72e-01
REACTOME SUMOYLATION OF IMMUNE RESPONSE PROTEINS 10 3.09e-01 -0.186000 7.72e-01
REACTOME DEFECTIVE B4GALT1 CAUSES B4GALT1 CDG CDG 2D 8 3.09e-01 -0.208000 7.72e-01
REACTOME TRP CHANNELS 27 3.10e-01 -0.113000 7.72e-01
REACTOME BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA 6 3.10e-01 -0.239000 7.72e-01
REACTOME METABOLISM OF STEROID HORMONES 35 3.11e-01 -0.098900 7.72e-01
REACTOME CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER 25 3.11e-01 -0.117000 7.72e-01
REACTOME GLYCOGEN SYNTHESIS 13 3.12e-01 0.162000 7.72e-01
REACTOME REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION 84 3.12e-01 0.063700 7.72e-01
REACTOME GENE SILENCING BY RNA 133 3.13e-01 0.050700 7.72e-01
REACTOME INTEGRATION OF ENERGY METABOLISM 105 3.13e-01 -0.057000 7.72e-01
REACTOME SIGNALING BY TGFB FAMILY MEMBERS 119 3.14e-01 0.053400 7.73e-01
REACTOME DISSOLUTION OF FIBRIN CLOT 13 3.15e-01 0.161000 7.73e-01
REACTOME TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER 76 3.16e-01 0.066600 7.73e-01
REACTOME ESR MEDIATED SIGNALING 210 3.16e-01 0.040200 7.73e-01
REACTOME SIGNALING BY ERYTHROPOIETIN 25 3.16e-01 0.116000 7.73e-01
REACTOME CD22 MEDIATED BCR REGULATION 5 3.16e-01 0.259000 7.73e-01
REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM 50 3.16e-01 -0.081900 7.73e-01
REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT 15 3.18e-01 -0.149000 7.75e-01
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE 105 3.20e-01 0.056200 7.77e-01
REACTOME SUMOYLATION OF INTRACELLULAR RECEPTORS 29 3.20e-01 0.107000 7.77e-01
REACTOME DOPAMINE RECEPTORS 5 3.20e-01 0.257000 7.77e-01
REACTOME RUNX2 REGULATES CHONDROCYTE MATURATION 5 3.21e-01 -0.256000 7.77e-01
REACTOME CONDENSATION OF PROMETAPHASE CHROMOSOMES 11 3.21e-01 0.173000 7.77e-01
REACTOME UB SPECIFIC PROCESSING PROTEASES 187 3.22e-01 0.042000 7.77e-01
REACTOME G PROTEIN MEDIATED EVENTS 53 3.22e-01 0.078600 7.77e-01
REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION 60 3.22e-01 0.073900 7.77e-01
REACTOME M PHASE 398 3.23e-01 0.028900 7.77e-01
REACTOME TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY 16 3.23e-01 0.143000 7.77e-01
REACTOME IRS ACTIVATION 5 3.24e-01 -0.255000 7.77e-01
REACTOME PI 3K CASCADE FGFR1 21 3.24e-01 0.124000 7.77e-01
REACTOME PI3K AKT SIGNALING IN CANCER 103 3.25e-01 0.056100 7.78e-01
REACTOME SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS 16 3.27e-01 0.142000 7.81e-01
REACTOME RHO GTPASES ACTIVATE CIT 19 3.27e-01 -0.130000 7.81e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION 27 3.28e-01 -0.109000 7.81e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE GIP 12 3.29e-01 0.163000 7.81e-01
REACTOME NOD1 2 SIGNALING PATHWAY 33 3.30e-01 0.098100 7.81e-01
REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS 15 3.30e-01 0.145000 7.81e-01
REACTOME POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION 27 3.30e-01 0.108000 7.81e-01
REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS 45 3.30e-01 0.083900 7.81e-01
REACTOME INTRA GOLGI TRAFFIC 43 3.31e-01 0.085700 7.81e-01
REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND 21 3.31e-01 0.122000 7.81e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE 5 3.32e-01 0.251000 7.81e-01
REACTOME SIGNALING BY FGFR4 40 3.32e-01 0.088700 7.81e-01
REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES 12 3.33e-01 0.161000 7.83e-01
REACTOME METALLOPROTEASE DUBS 36 3.34e-01 0.093100 7.83e-01
REACTOME TRNA PROCESSING 105 3.35e-01 -0.054400 7.84e-01
REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION 183 3.37e-01 0.041200 7.84e-01
REACTOME G0 AND EARLY G1 27 3.37e-01 0.107000 7.84e-01
REACTOME FGFR2 ALTERNATIVE SPLICING 27 3.38e-01 0.107000 7.84e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH RAS 8 3.39e-01 0.195000 7.84e-01
REACTOME PCP CE PATHWAY 91 3.39e-01 0.058000 7.84e-01
REACTOME TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS 52 3.39e-01 0.076600 7.84e-01
REACTOME TAK1 DEPENDENT IKK AND NF KAPPA B ACTIVATION 41 3.40e-01 0.086200 7.84e-01
REACTOME ENDOGENOUS STEROLS 26 3.40e-01 -0.108000 7.84e-01
REACTOME SIGNALING BY NOTCH 234 3.40e-01 0.036200 7.84e-01
REACTOME DNA METHYLATION 58 3.40e-01 0.072400 7.84e-01
REACTOME DEFECTIVE CHST14 CAUSES EDS MUSCULOCONTRACTURAL TYPE 7 3.40e-01 0.208000 7.84e-01
REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING 34 3.40e-01 0.094500 7.84e-01
REACTOME CHREBP ACTIVATES METABOLIC GENE EXPRESSION 8 3.43e-01 -0.194000 7.88e-01
REACTOME PLATELET CALCIUM HOMEOSTASIS 27 3.43e-01 0.105000 7.88e-01
REACTOME MAP2K AND MAPK ACTIVATION 38 3.46e-01 0.088400 7.92e-01
REACTOME INTERLEUKIN 23 SIGNALING 9 3.46e-01 0.181000 7.92e-01
REACTOME ADRENOCEPTORS 9 3.47e-01 0.181000 7.92e-01
REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE 37 3.48e-01 -0.089200 7.92e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX 19 3.48e-01 0.124000 7.92e-01
REACTOME NRCAM INTERACTIONS 6 3.48e-01 -0.221000 7.92e-01
REACTOME DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1 9 3.48e-01 0.181000 7.92e-01
REACTOME PROTEIN REPAIR 6 3.49e-01 0.221000 7.92e-01
REACTOME IRS MEDIATED SIGNALLING 47 3.50e-01 0.078900 7.92e-01
REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING 30 3.52e-01 0.098200 7.92e-01
REACTOME CHAPERONE MEDIATED AUTOPHAGY 20 3.52e-01 -0.120000 7.92e-01
REACTOME CITRIC ACID CYCLE TCA CYCLE 21 3.52e-01 0.117000 7.92e-01
REACTOME GABA B RECEPTOR ACTIVATION 43 3.53e-01 -0.081900 7.92e-01
REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES 37 3.54e-01 -0.088100 7.92e-01
REACTOME MET ACTIVATES PI3K AKT SIGNALING 6 3.54e-01 0.219000 7.92e-01
REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING 32 3.54e-01 0.094700 7.92e-01
REACTOME PROTON COUPLED MONOCARBOXYLATE TRANSPORT 6 3.54e-01 0.219000 7.92e-01
REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS 12 3.55e-01 -0.154000 7.92e-01
REACTOME IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN 5 3.55e-01 -0.239000 7.92e-01
REACTOME CYP2E1 REACTIONS 10 3.56e-01 -0.168000 7.92e-01
REACTOME AQUAPORIN MEDIATED TRANSPORT 51 3.56e-01 -0.074600 7.92e-01
REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS 93 3.57e-01 0.055300 7.92e-01
REACTOME INLA MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS 9 3.57e-01 0.177000 7.92e-01
REACTOME UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN 6 3.57e-01 0.217000 7.92e-01
REACTOME PURINE SALVAGE 12 3.58e-01 0.153000 7.92e-01
REACTOME CONDENSATION OF PROPHASE CHROMOSOMES 66 3.58e-01 0.065400 7.92e-01
REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS 68 3.59e-01 0.064300 7.92e-01
REACTOME COMPLEX I BIOGENESIS 49 3.60e-01 0.075700 7.92e-01
REACTOME METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES 33 3.60e-01 -0.092100 7.92e-01
REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX 32 3.61e-01 0.093200 7.92e-01
REACTOME DERMATAN SULFATE BIOSYNTHESIS 10 3.62e-01 0.166000 7.92e-01
REACTOME FGFR1C LIGAND BINDING AND ACTIVATION 11 3.62e-01 0.159000 7.92e-01
REACTOME TNFR1 INDUCED PROAPOPTOTIC SIGNALING 23 3.62e-01 -0.110000 7.92e-01
REACTOME VITAMIN D CALCIFEROL METABOLISM 12 3.63e-01 0.152000 7.92e-01
REACTOME FRS MEDIATED FGFR2 SIGNALING 24 3.63e-01 0.107000 7.92e-01
REACTOME SUMOYLATION OF DNA REPLICATION PROTEINS 46 3.65e-01 -0.077300 7.92e-01
REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 122 3.65e-01 0.047500 7.92e-01
REACTOME DISEASES OF MITOTIC CELL CYCLE 37 3.65e-01 0.086000 7.92e-01
REACTOME PRE NOTCH EXPRESSION AND PROCESSING 112 3.66e-01 0.049500 7.92e-01
REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY 46 3.66e-01 0.077000 7.92e-01
REACTOME ER QUALITY CONTROL COMPARTMENT ERQC 21 3.66e-01 0.114000 7.92e-01
REACTOME RHO GTPASE EFFECTORS 305 3.67e-01 0.030000 7.92e-01
REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE 93 3.67e-01 0.054100 7.92e-01
REACTOME PEXOPHAGY 11 3.68e-01 0.157000 7.92e-01
REACTOME TRAFFICKING OF AMPA RECEPTORS 29 3.68e-01 -0.096700 7.92e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES 16 3.68e-01 0.130000 7.92e-01
REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING 12 3.68e-01 -0.150000 7.92e-01
REACTOME SERINE BIOSYNTHESIS 9 3.68e-01 0.173000 7.92e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION TERMINATION 23 3.68e-01 0.108000 7.92e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS 14 3.71e-01 0.138000 7.95e-01
REACTOME INTERLEUKIN 20 FAMILY SIGNALING 25 3.72e-01 0.103000 7.95e-01
REACTOME METABOLISM OF POLYAMINES 56 3.72e-01 0.068900 7.95e-01
REACTOME RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY 14 3.73e-01 0.137000 7.95e-01
REACTOME SYNTHESIS OF PA 38 3.74e-01 -0.083400 7.95e-01
REACTOME FOLDING OF ACTIN BY CCT TRIC 10 3.74e-01 0.162000 7.95e-01
REACTOME SOS MEDIATED SIGNALLING 7 3.75e-01 0.194000 7.95e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR2 29 3.75e-01 0.095200 7.95e-01
REACTOME HIV TRANSCRIPTION ELONGATION 42 3.77e-01 0.078800 7.95e-01
REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY 5 3.77e-01 0.228000 7.95e-01
REACTOME ROLE OF ABL IN ROBO SLIT SIGNALING 8 3.77e-01 0.180000 7.95e-01
REACTOME METABOLISM OF LIPIDS 709 3.78e-01 0.019400 7.95e-01
REACTOME ACETYLCHOLINE REGULATES INSULIN SECRETION 10 3.78e-01 0.161000 7.95e-01
REACTOME DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A 5 3.79e-01 -0.227000 7.95e-01
REACTOME RRNA PROCESSING 192 3.79e-01 0.036800 7.95e-01
REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS 123 3.79e-01 0.045900 7.95e-01
REACTOME FGFR1 LIGAND BINDING AND ACTIVATION 15 3.80e-01 0.131000 7.95e-01
REACTOME UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION 19 3.80e-01 0.116000 7.95e-01
REACTOME WNT MEDIATED ACTIVATION OF DVL 8 3.80e-01 0.179000 7.95e-01
REACTOME SIGNALING BY FGFR 85 3.80e-01 0.055100 7.95e-01
REACTOME NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 19 3.81e-01 -0.116000 7.95e-01
REACTOME INTERLEUKIN RECEPTOR SHC SIGNALING 24 3.81e-01 0.103000 7.95e-01
REACTOME RHOF GTPASE CYCLE 40 3.81e-01 0.080000 7.95e-01
REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM 23 3.82e-01 0.105000 7.95e-01
REACTOME MTOR SIGNALLING 40 3.84e-01 0.079500 7.99e-01
REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES 46 3.84e-01 0.074200 7.99e-01
REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE 66 3.86e-01 0.061800 8.00e-01
REACTOME VLDL CLEARANCE 6 3.86e-01 0.204000 8.00e-01
REACTOME PI 3K CASCADE FGFR3 17 3.87e-01 0.121000 8.01e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE 5 3.87e-01 0.223000 8.01e-01
REACTOME FC EPSILON RECEPTOR FCERI SIGNALING 127 3.88e-01 0.044400 8.01e-01
REACTOME AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY 8 3.89e-01 0.176000 8.02e-01
REACTOME GDP FUCOSE BIOSYNTHESIS 6 3.90e-01 0.203000 8.03e-01
REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX 9 3.91e-01 0.165000 8.04e-01
REACTOME VLDL ASSEMBLY 5 3.91e-01 0.221000 8.04e-01
REACTOME INTERLEUKIN 7 SIGNALING 31 3.92e-01 0.088800 8.04e-01
REACTOME SYNTHESIS OF KETONE BODIES 8 3.92e-01 -0.175000 8.04e-01
REACTOME MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION 15 3.93e-01 0.127000 8.05e-01
REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND 14 3.94e-01 0.132000 8.05e-01
REACTOME GLYCOSPHINGOLIPID METABOLISM 39 3.95e-01 0.078800 8.05e-01
REACTOME REGULATION OF PTEN LOCALIZATION 8 3.95e-01 0.174000 8.05e-01
REACTOME FATTY ACIDS 15 3.95e-01 -0.127000 8.05e-01
REACTOME SIGNALING BY FGFR3 39 3.96e-01 0.078600 8.05e-01
REACTOME MUCOPOLYSACCHARIDOSES 10 3.98e-01 -0.154000 8.09e-01
REACTOME GLYCOGEN STORAGE DISEASES 15 3.99e-01 0.126000 8.10e-01
REACTOME ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS 20 4.00e-01 0.109000 8.11e-01
REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS 17 4.01e-01 -0.118000 8.11e-01
REACTOME TELOMERE MAINTENANCE 106 4.02e-01 0.047100 8.11e-01
REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS 42 4.02e-01 -0.074700 8.11e-01
REACTOME CRMPS IN SEMA3A SIGNALING 15 4.03e-01 -0.125000 8.11e-01
REACTOME PHASE II CONJUGATION OF COMPOUNDS 102 4.03e-01 -0.047900 8.11e-01
REACTOME PI 3K CASCADE FGFR4 19 4.04e-01 0.111000 8.12e-01
REACTOME OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS 8 4.05e-01 0.170000 8.12e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION 36 4.05e-01 0.080200 8.12e-01
REACTOME EUKARYOTIC TRANSLATION ELONGATION 87 4.05e-01 0.051700 8.12e-01
REACTOME ERK MAPK TARGETS 20 4.06e-01 -0.107000 8.12e-01
REACTOME PREVENTION OF PHAGOSOMAL LYSOSOMAL FUSION 9 4.07e-01 0.160000 8.12e-01
REACTOME TYSND1 CLEAVES PEROXISOMAL PROTEINS 7 4.07e-01 0.181000 8.12e-01
REACTOME REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE 81 4.07e-01 0.053200 8.12e-01
REACTOME INWARDLY RECTIFYING K CHANNELS 35 4.08e-01 -0.080900 8.12e-01
REACTOME PEROXISOMAL LIPID METABOLISM 28 4.08e-01 -0.090400 8.12e-01
REACTOME REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO 10 4.09e-01 0.151000 8.12e-01
REACTOME INTERLEUKIN 21 SIGNALING 9 4.09e-01 0.159000 8.12e-01
REACTOME TNF SIGNALING 54 4.10e-01 -0.064800 8.13e-01
REACTOME LRR FLII INTERACTING PROTEIN 1 LRRFIP1 ACTIVATES TYPE I IFN PRODUCTION 5 4.11e-01 -0.212000 8.13e-01
REACTOME SARS COV 2 MODULATES AUTOPHAGY 11 4.11e-01 0.143000 8.14e-01
REACTOME CONSTITUTIVE SIGNALING BY EGFRVIII 15 4.13e-01 0.122000 8.16e-01
REACTOME REGULATION OF NPAS4 GENE TRANSCRIPTION 5 4.15e-01 0.210000 8.19e-01
REACTOME ACTIVATION OF TRKA RECEPTORS 6 4.16e-01 -0.192000 8.21e-01
REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING 28 4.17e-01 0.088600 8.21e-01
REACTOME GPVI MEDIATED ACTIVATION CASCADE 35 4.19e-01 0.079000 8.23e-01
REACTOME CIRCADIAN CLOCK 68 4.19e-01 0.056700 8.23e-01
REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS 46 4.20e-01 0.068800 8.23e-01
REACTOME PROLONGED ERK ACTIVATION EVENTS 14 4.20e-01 0.124000 8.23e-01
REACTOME RUNX2 REGULATES BONE DEVELOPMENT 29 4.21e-01 -0.086400 8.23e-01
REACTOME ERKS ARE INACTIVATED 13 4.22e-01 -0.129000 8.24e-01
REACTOME CHROMATIN MODIFYING ENZYMES 252 4.22e-01 0.029400 8.24e-01
REACTOME POLB DEPENDENT LONG PATCH BASE EXCISION REPAIR 8 4.22e-01 -0.164000 8.24e-01
REACTOME DNA DAMAGE RECOGNITION IN GG NER 36 4.25e-01 0.076800 8.27e-01
REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING 30 4.25e-01 0.084100 8.27e-01
REACTOME ABACAVIR TRANSMEMBRANE TRANSPORT 5 4.26e-01 -0.206000 8.27e-01
REACTOME RHO GTPASES ACTIVATE PKNS 86 4.27e-01 0.049600 8.28e-01
REACTOME MAPK6 MAPK4 SIGNALING 91 4.27e-01 0.048100 8.28e-01
REACTOME SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION 8 4.29e-01 -0.162000 8.30e-01
REACTOME THE PHOTOTRANSDUCTION CASCADE 32 4.29e-01 -0.080700 8.30e-01
REACTOME RAP1 SIGNALLING 16 4.30e-01 0.114000 8.32e-01
REACTOME TRANSCRIPTIONAL REGULATION BY E2F6 32 4.31e-01 0.080400 8.32e-01
REACTOME ETHANOL OXIDATION 12 4.32e-01 0.131000 8.32e-01
REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION 19 4.33e-01 0.104000 8.33e-01
REACTOME PIWI INTERACTING RNA PIRNA BIOGENESIS 29 4.34e-01 0.084000 8.33e-01
REACTOME SIGNALING BY FGFR2 IIIA TM 19 4.34e-01 0.104000 8.33e-01
REACTOME SEPARATION OF SISTER CHROMATIDS 184 4.36e-01 0.033300 8.33e-01
REACTOME FCERI MEDIATED NF KB ACTIVATION 78 4.36e-01 0.051000 8.33e-01
REACTOME REGULATED PROTEOLYSIS OF P75NTR 11 4.36e-01 0.136000 8.33e-01
REACTOME MULTIFUNCTIONAL ANION EXCHANGERS 9 4.37e-01 -0.150000 8.33e-01
REACTOME INSULIN RECEPTOR SIGNALLING CASCADE 53 4.37e-01 0.061700 8.33e-01
REACTOME ER TO GOLGI ANTEROGRADE TRANSPORT 152 4.38e-01 0.036500 8.33e-01
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY 94 4.38e-01 0.046200 8.33e-01
REACTOME NGF INDEPENDANT TRKA ACTIVATION 5 4.38e-01 -0.200000 8.33e-01
REACTOME MICRORNA MIRNA BIOGENESIS 25 4.40e-01 0.089200 8.33e-01
REACTOME HEDGEHOG OFF STATE 111 4.41e-01 0.042400 8.33e-01
REACTOME G ALPHA S SIGNALLING EVENTS 155 4.41e-01 -0.035900 8.33e-01
REACTOME POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE 25 4.41e-01 -0.089000 8.33e-01
REACTOME GLUCAGON TYPE LIGAND RECEPTORS 32 4.41e-01 -0.078600 8.33e-01
REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION 23 4.42e-01 0.092700 8.33e-01
REACTOME SEMAPHORIN INTERACTIONS 61 4.42e-01 -0.057000 8.33e-01
REACTOME TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7 12 4.42e-01 0.128000 8.33e-01
REACTOME HDL ASSEMBLY 8 4.43e-01 -0.157000 8.33e-01
REACTOME CD163 MEDIATING AN ANTI INFLAMMATORY RESPONSE 9 4.44e-01 0.147000 8.33e-01
REACTOME KERATAN SULFATE DEGRADATION 13 4.44e-01 -0.123000 8.33e-01
REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS 23 4.44e-01 -0.092100 8.33e-01
REACTOME MITOPHAGY 28 4.44e-01 0.083500 8.33e-01
REACTOME KILLING MECHANISMS 11 4.45e-01 -0.133000 8.33e-01
REACTOME NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION 20 4.46e-01 0.098500 8.34e-01
REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE 69 4.47e-01 -0.052900 8.34e-01
REACTOME RHO GTPASES ACTIVATE KTN1 11 4.47e-01 0.132000 8.34e-01
REACTOME RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA 7 4.48e-01 -0.166000 8.34e-01
REACTOME HSF1 DEPENDENT TRANSACTIVATION 37 4.49e-01 0.072000 8.34e-01
REACTOME CELLULAR HEXOSE TRANSPORT 21 4.49e-01 -0.095500 8.34e-01
REACTOME DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA 77 4.49e-01 0.049900 8.34e-01
REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK 28 4.51e-01 0.082300 8.36e-01
REACTOME COENZYME A BIOSYNTHESIS 8 4.51e-01 0.154000 8.36e-01
REACTOME NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 11 4.52e-01 0.131000 8.36e-01
REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS 20 4.54e-01 -0.096800 8.36e-01
REACTOME CARDIAC CONDUCTION 125 4.54e-01 -0.038800 8.36e-01
REACTOME PHASE 3 RAPID REPOLARISATION 8 4.54e-01 0.153000 8.36e-01
REACTOME RHOH GTPASE CYCLE 37 4.54e-01 0.071100 8.36e-01
REACTOME RHOQ GTPASE CYCLE 57 4.55e-01 -0.057200 8.36e-01
REACTOME REGULATION OF PTEN STABILITY AND ACTIVITY 67 4.56e-01 0.052700 8.36e-01
REACTOME EPH EPHRIN MEDIATED REPULSION OF CELLS 50 4.56e-01 0.061000 8.36e-01
REACTOME THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT 77 4.56e-01 0.049100 8.36e-01
REACTOME REGULATION OF MECP2 EXPRESSION AND ACTIVITY 30 4.56e-01 0.078600 8.36e-01
REACTOME SNRNP ASSEMBLY 53 4.57e-01 0.059000 8.37e-01
REACTOME REDUCTION OF CYTOSOLIC CA LEVELS 11 4.57e-01 -0.129000 8.37e-01
REACTOME INACTIVATION OF CSF3 G CSF SIGNALING 25 4.59e-01 0.085600 8.38e-01
REACTOME VIRAL MESSENGER RNA SYNTHESIS 44 4.59e-01 0.064500 8.38e-01
REACTOME ACTIVATION OF NIMA KINASES NEK9 NEK6 NEK7 7 4.61e-01 0.161000 8.39e-01
REACTOME METABOLISM OF PORPHYRINS 26 4.61e-01 0.083500 8.39e-01
REACTOME SEMA4D IN SEMAPHORIN SIGNALING 24 4.62e-01 -0.086800 8.39e-01
REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION 9 4.62e-01 0.142000 8.39e-01
REACTOME PHOSPHORYLATION OF THE APC C 20 4.64e-01 0.094500 8.41e-01
REACTOME TRNA MODIFICATION IN THE MITOCHONDRION 8 4.65e-01 -0.149000 8.41e-01
REACTOME DECTIN 2 FAMILY 26 4.65e-01 -0.082800 8.41e-01
REACTOME GPER1 SIGNALING 45 4.65e-01 -0.062900 8.41e-01
REACTOME COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING 32 4.66e-01 0.074500 8.41e-01
REACTOME SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER 15 4.66e-01 -0.109000 8.41e-01
REACTOME RAS PROCESSING 22 4.67e-01 0.089700 8.41e-01
REACTOME INACTIVATION OF CDC42 AND RAC1 8 4.68e-01 -0.148000 8.42e-01
REACTOME MITOTIC METAPHASE AND ANAPHASE 228 4.69e-01 0.027800 8.42e-01
REACTOME RECYCLING PATHWAY OF L1 43 4.69e-01 -0.063800 8.42e-01
REACTOME INTRAFLAGELLAR TRANSPORT 50 4.70e-01 0.059100 8.42e-01
REACTOME AMINO ACIDS REGULATE MTORC1 53 4.71e-01 0.057300 8.42e-01
REACTOME BUDDING AND MATURATION OF HIV VIRION 28 4.72e-01 0.078600 8.42e-01
REACTOME OVARIAN TUMOR DOMAIN PROTEASES 36 4.72e-01 0.069300 8.42e-01
REACTOME RHOB GTPASE CYCLE 67 4.72e-01 0.050800 8.42e-01
REACTOME ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY 5 4.74e-01 0.185000 8.42e-01
REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS 12 4.75e-01 -0.119000 8.42e-01
REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS 83 4.75e-01 0.045300 8.42e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS 6 4.75e-01 0.168000 8.42e-01
REACTOME BETA DEFENSINS 27 4.76e-01 0.079300 8.42e-01
REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES 80 4.78e-01 0.045900 8.42e-01
REACTOME E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS 58 4.78e-01 0.053900 8.42e-01
REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA 28 4.78e-01 0.077500 8.42e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES 43 4.78e-01 0.062500 8.42e-01
REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES 7 4.78e-01 0.155000 8.42e-01
REACTOME HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS 9 4.78e-01 -0.136000 8.42e-01
REACTOME ALK MUTANTS BIND TKIS 12 4.80e-01 0.118000 8.42e-01
REACTOME JOSEPHIN DOMAIN DUBS 11 4.80e-01 0.123000 8.42e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN 13 4.81e-01 0.113000 8.42e-01
REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS 27 4.81e-01 -0.078400 8.42e-01
REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE 9 4.83e-01 -0.135000 8.42e-01
REACTOME VITAMIN B2 RIBOFLAVIN METABOLISM 7 4.83e-01 0.153000 8.42e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS 7 4.83e-01 0.153000 8.42e-01
REACTOME SYNAPTIC ADHESION LIKE MOLECULES 19 4.84e-01 -0.092800 8.42e-01
REACTOME RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS 5 4.84e-01 0.181000 8.42e-01
REACTOME REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR 11 4.84e-01 0.122000 8.42e-01
REACTOME CYTOPROTECTION BY HMOX1 59 4.84e-01 0.052600 8.42e-01
REACTOME RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION 6 4.85e-01 -0.165000 8.42e-01
REACTOME 2 LTR CIRCLE FORMATION 7 4.85e-01 0.152000 8.42e-01
REACTOME HATS ACETYLATE HISTONES 129 4.85e-01 0.035600 8.42e-01
REACTOME PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING 5 4.86e-01 0.180000 8.42e-01
REACTOME MYD88 INDEPENDENT TLR4 CASCADE 103 4.86e-01 0.039700 8.42e-01
REACTOME NR1H2 AND NR1H3 MEDIATED SIGNALING 46 4.86e-01 -0.059300 8.42e-01
REACTOME BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA 5 4.86e-01 -0.180000 8.42e-01
REACTOME HS GAG BIOSYNTHESIS 28 4.87e-01 -0.075900 8.42e-01
REACTOME KETONE BODY METABOLISM 9 4.87e-01 -0.134000 8.42e-01
REACTOME DEFENSINS 33 4.89e-01 0.069600 8.44e-01
REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS 32 4.90e-01 0.070500 8.45e-01
REACTOME GLUCONEOGENESIS 33 4.90e-01 0.069400 8.45e-01
REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY 25 4.92e-01 -0.079500 8.45e-01
REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING 25 4.92e-01 0.079400 8.45e-01
REACTOME ESTROGEN BIOSYNTHESIS 6 4.92e-01 -0.162000 8.45e-01
REACTOME SCAVENGING BY CLASS A RECEPTORS 19 4.93e-01 -0.090900 8.45e-01
REACTOME CALCINEURIN ACTIVATES NFAT 9 4.94e-01 -0.132000 8.47e-01
REACTOME CYTOCHROME C MEDIATED APOPTOTIC RESPONSE 12 4.96e-01 0.114000 8.47e-01
REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER 18 4.97e-01 0.092600 8.47e-01
REACTOME SODIUM PROTON EXCHANGERS 7 4.97e-01 -0.148000 8.47e-01
REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV 1 INFECTION 5 4.97e-01 -0.175000 8.47e-01
REACTOME MHC CLASS II ANTIGEN PRESENTATION 121 4.98e-01 0.035700 8.47e-01
REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR 79 5.00e-01 0.043900 8.47e-01
REACTOME TOXICITY OF BOTULINUM TOXIN TYPE D BOTD 5 5.00e-01 -0.174000 8.47e-01
REACTOME NUCLEAR SIGNALING BY ERBB4 32 5.01e-01 0.068800 8.47e-01
REACTOME DEPOLYMERISATION OF THE NUCLEAR LAMINA 14 5.01e-01 -0.104000 8.47e-01
REACTOME RAF ACTIVATION 33 5.01e-01 0.067700 8.47e-01
REACTOME SIGNALING BY FGFR1 49 5.01e-01 0.055500 8.47e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH PI3K 6 5.01e-01 -0.159000 8.47e-01
REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A 26 5.01e-01 0.076200 8.47e-01
REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS 5 5.02e-01 -0.174000 8.47e-01
REACTOME FCERI MEDIATED CA 2 MOBILIZATION 30 5.03e-01 0.070700 8.48e-01
REACTOME FATTY ACIDS BOUND TO GPR40 FFAR1 REGULATE INSULIN SECRETION 8 5.05e-01 0.136000 8.48e-01
REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK 17 5.05e-01 0.093400 8.48e-01
REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS 21 5.05e-01 0.084000 8.48e-01
REACTOME P75NTR REGULATES AXONOGENESIS 9 5.05e-01 -0.128000 8.48e-01
REACTOME SIGNALING BY LRP5 MUTANTS 6 5.06e-01 0.157000 8.48e-01
REACTOME PLASMA LIPOPROTEIN CLEARANCE 37 5.06e-01 0.063100 8.48e-01
REACTOME PURINE CATABOLISM 17 5.07e-01 0.093000 8.48e-01
REACTOME INTERLEUKIN 9 SIGNALING 7 5.07e-01 0.145000 8.48e-01
REACTOME HIV ELONGATION ARREST AND RECOVERY 33 5.07e-01 0.066700 8.48e-01
REACTOME CHONDROITIN SULFATE BIOSYNTHESIS 18 5.08e-01 0.090200 8.48e-01
REACTOME LYSINE CATABOLISM 12 5.10e-01 0.110000 8.51e-01
REACTOME AUTOPHAGY 144 5.11e-01 0.031700 8.52e-01
REACTOME SYNTHESIS OF PI 5 5.12e-01 -0.169000 8.52e-01
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION 81 5.16e-01 0.041700 8.57e-01
REACTOME TERMINATION OF TRANSLESION DNA SYNTHESIS 32 5.17e-01 0.066300 8.57e-01
REACTOME RECEPTOR MEDIATED MITOPHAGY 10 5.18e-01 0.118000 8.57e-01
REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY 15 5.18e-01 -0.096500 8.57e-01
REACTOME RIP MEDIATED NFKB ACTIVATION VIA ZBP1 16 5.18e-01 0.093300 8.57e-01
REACTOME COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM 21 5.18e-01 -0.081500 8.57e-01
REACTOME INTERFERON SIGNALING 193 5.18e-01 0.027000 8.57e-01
REACTOME CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE 49 5.20e-01 -0.053200 8.57e-01
REACTOME HCMV LATE EVENTS 110 5.20e-01 0.035500 8.57e-01
REACTOME MISCELLANEOUS SUBSTRATES 12 5.21e-01 -0.107000 8.57e-01
REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3 679 5.22e-01 0.014400 8.57e-01
REACTOME CELLULAR RESPONSE TO HEAT STRESS 99 5.23e-01 0.037100 8.57e-01
REACTOME MRNA EDITING 10 5.23e-01 0.117000 8.57e-01
REACTOME AURKA ACTIVATION BY TPX2 69 5.24e-01 0.044400 8.57e-01
REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT 222 5.24e-01 0.024800 8.57e-01
REACTOME CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT 19 5.24e-01 0.084400 8.57e-01
REACTOME SIGNALING BY ERBB2 ECD MUTANTS 16 5.24e-01 0.092000 8.57e-01
REACTOME DEFECTIVE F9 ACTIVATION 5 5.24e-01 0.164000 8.57e-01
REACTOME PYRIMIDINE CATABOLISM 12 5.25e-01 0.106000 8.57e-01
REACTOME CROSS PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS PHAGOSOMES 6 5.26e-01 -0.149000 8.58e-01
REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION 20 5.26e-01 0.081800 8.58e-01
REACTOME DCC MEDIATED ATTRACTIVE SIGNALING 14 5.29e-01 -0.097200 8.61e-01
REACTOME NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 11 5.30e-01 0.109000 8.61e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE 8 5.30e-01 0.128000 8.61e-01
REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION 42 5.31e-01 -0.055800 8.61e-01
REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC 28 5.32e-01 0.068300 8.61e-01
REACTOME ATTENUATION PHASE 27 5.32e-01 0.069500 8.61e-01
REACTOME CD28 CO STIMULATION 32 5.33e-01 0.063700 8.61e-01
REACTOME N GLYCAN TRIMMING AND ELONGATION IN THE CIS GOLGI 5 5.33e-01 0.161000 8.61e-01
REACTOME SIGNALING BY WNT 318 5.34e-01 0.020300 8.61e-01
REACTOME MRNA SPLICING MINOR PATHWAY 49 5.34e-01 0.051400 8.61e-01
REACTOME PASSIVE TRANSPORT BY AQUAPORINS 13 5.34e-01 -0.099600 8.61e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL 15 5.34e-01 -0.092700 8.61e-01
REACTOME SUMOYLATION OF TRANSCRIPTION FACTORS 20 5.36e-01 0.079900 8.63e-01
REACTOME RHO GTPASES ACTIVATE IQGAPS 31 5.38e-01 -0.063900 8.65e-01
REACTOME MET ACTIVATES PTPN11 5 5.39e-01 0.159000 8.66e-01
REACTOME RHOU GTPASE CYCLE 37 5.39e-01 0.058300 8.66e-01
REACTOME CA2 PATHWAY 62 5.40e-01 -0.045000 8.66e-01
REACTOME ACYL CHAIN REMODELING OF CL 5 5.42e-01 -0.157000 8.69e-01
REACTOME FASL CD95L SIGNALING 5 5.45e-01 0.156000 8.73e-01
REACTOME INFECTION WITH MYCOBACTERIUM TUBERCULOSIS 25 5.46e-01 0.069800 8.73e-01
REACTOME NADE MODULATES DEATH SIGNALLING 5 5.46e-01 -0.156000 8.73e-01
REACTOME BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA 17 5.49e-01 -0.083900 8.77e-01
REACTOME VOLTAGE GATED POTASSIUM CHANNELS 42 5.50e-01 0.053300 8.77e-01
REACTOME METABOLISM OF COFACTORS 19 5.52e-01 0.078800 8.77e-01
REACTOME METHYLATION 14 5.52e-01 -0.091800 8.77e-01
REACTOME NEF MEDIATED CD4 DOWN REGULATION 9 5.52e-01 -0.114000 8.77e-01
REACTOME SIGNALING BY FGFR4 IN DISEASE 11 5.53e-01 0.103000 8.77e-01
REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING 33 5.53e-01 0.059600 8.77e-01
REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES 101 5.54e-01 -0.034100 8.77e-01
REACTOME MITOTIC PROMETAPHASE 194 5.54e-01 0.024600 8.77e-01
REACTOME NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10 12 5.55e-01 0.098400 8.78e-01
REACTOME ONCOGENIC MAPK SIGNALING 79 5.57e-01 0.038200 8.80e-01
REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN 15 5.58e-01 0.087300 8.80e-01
REACTOME RA BIOSYNTHESIS PATHWAY 22 5.58e-01 0.072100 8.80e-01
REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX 85 5.59e-01 -0.036700 8.80e-01
REACTOME HDR THROUGH MMEJ ALT NHEJ 12 5.59e-01 0.097400 8.80e-01
REACTOME FORMATION OF APOPTOSOME 10 5.59e-01 0.107000 8.80e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH CDK5 6 5.60e-01 -0.137000 8.80e-01
REACTOME CD28 DEPENDENT VAV1 PATHWAY 11 5.62e-01 0.101000 8.83e-01
REACTOME FATTY ACID METABOLISM 170 5.63e-01 0.025700 8.83e-01
REACTOME ARMS MEDIATED ACTIVATION 7 5.64e-01 0.126000 8.83e-01
REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS 11 5.65e-01 0.100000 8.84e-01
REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM 78 5.66e-01 0.037600 8.84e-01
REACTOME UBIQUINOL BIOSYNTHESIS 8 5.66e-01 0.117000 8.84e-01
REACTOME NICOTINAMIDE SALVAGING 19 5.66e-01 -0.076000 8.84e-01
REACTOME ENDOSOMAL VACUOLAR PATHWAY 11 5.68e-01 0.099500 8.84e-01
REACTOME PI 3K CASCADE FGFR2 22 5.68e-01 0.070300 8.84e-01
REACTOME SYNTHESIS OF DIPHTHAMIDE EEF2 8 5.69e-01 0.116000 8.84e-01
REACTOME REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA 15 5.70e-01 0.084800 8.84e-01
REACTOME REGULATION OF INSULIN SECRETION 77 5.70e-01 -0.037500 8.84e-01
REACTOME SIALIC ACID METABOLISM 33 5.71e-01 0.057000 8.84e-01
REACTOME NEUROTRANSMITTER RELEASE CYCLE 48 5.71e-01 0.047300 8.84e-01
REACTOME PARASITE INFECTION 57 5.71e-01 0.043300 8.84e-01
REACTOME ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION 28 5.72e-01 -0.061800 8.84e-01
REACTOME VLDLR INTERNALISATION AND DEGRADATION 16 5.72e-01 0.081600 8.84e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY DVL INTERACTING PROTEINS 5 5.72e-01 -0.146000 8.84e-01
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY 33 5.73e-01 0.056700 8.84e-01
REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS 63 5.74e-01 0.041000 8.84e-01
REACTOME DSCAM INTERACTIONS 11 5.74e-01 -0.097800 8.84e-01
REACTOME PI METABOLISM 79 5.75e-01 0.036500 8.84e-01
REACTOME CREB PHOSPHORYLATION 6 5.75e-01 -0.132000 8.84e-01
REACTOME DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX 83 5.75e-01 0.035600 8.84e-01
REACTOME DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE 76 5.76e-01 0.037100 8.84e-01
REACTOME GLUCOCORTICOID BIOSYNTHESIS 10 5.77e-01 0.102000 8.84e-01
REACTOME AGGREPHAGY 42 5.78e-01 -0.049600 8.85e-01
REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB 19 5.78e-01 -0.073600 8.85e-01
REACTOME NEUROFASCIN INTERACTIONS 6 5.79e-01 -0.131000 8.85e-01
REACTOME RUNX3 REGULATES P14 ARF 10 5.80e-01 -0.101000 8.85e-01
REACTOME CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND 9 5.81e-01 -0.106000 8.85e-01
REACTOME DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE 30 5.81e-01 -0.058200 8.85e-01
REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS 16 5.81e-01 -0.079700 8.85e-01
REACTOME NTRK2 ACTIVATES RAC1 5 5.81e-01 -0.142000 8.85e-01
REACTOME RND1 GTPASE CYCLE 41 5.82e-01 0.049700 8.85e-01
REACTOME PLASMA LIPOPROTEIN REMODELING 33 5.84e-01 -0.055100 8.85e-01
REACTOME DEADENYLATION DEPENDENT MRNA DECAY 56 5.85e-01 0.042200 8.85e-01
REACTOME HEME SIGNALING 47 5.85e-01 0.046100 8.85e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12 22 5.85e-01 0.067200 8.85e-01
REACTOME VITAMIN B5 PANTOTHENATE METABOLISM 16 5.86e-01 0.078700 8.85e-01
REACTOME MITOTIC PROPHASE 134 5.86e-01 0.027300 8.85e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS 7 5.86e-01 -0.119000 8.85e-01
REACTOME ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE 9 5.87e-01 0.105000 8.86e-01
REACTOME PROTEIN UBIQUITINATION 76 5.88e-01 0.036000 8.86e-01
REACTOME PD 1 SIGNALING 21 5.89e-01 -0.068100 8.87e-01
REACTOME CREATINE METABOLISM 9 5.89e-01 0.104000 8.87e-01
REACTOME NEURONAL SYSTEM 388 5.92e-01 -0.015800 8.89e-01
REACTOME RHOD GTPASE CYCLE 49 5.93e-01 0.044100 8.89e-01
REACTOME TRNA AMINOACYLATION 40 5.93e-01 0.048800 8.89e-01
REACTOME ACTIVATION OF CASPASES THROUGH APOPTOSOME MEDIATED CLEAVAGE 5 5.93e-01 -0.138000 8.89e-01
REACTOME TRANSPORT OF ORGANIC ANIONS 10 5.93e-01 0.097500 8.89e-01
REACTOME TRIGLYCERIDE BIOSYNTHESIS 12 5.97e-01 -0.088300 8.92e-01
REACTOME DEX H BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION 7 5.97e-01 0.115000 8.92e-01
REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS 6 5.97e-01 0.125000 8.92e-01
REACTOME METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION 15 5.99e-01 -0.078400 8.94e-01
REACTOME DEFECTS IN VITAMIN AND COFACTOR METABOLISM 21 6.00e-01 0.066200 8.94e-01
REACTOME PHOSPHORYLATION OF EMI1 6 6.00e-01 -0.124000 8.94e-01
REACTOME MITOTIC SPINDLE CHECKPOINT 109 6.01e-01 0.029000 8.94e-01
REACTOME RELEASE OF HH NP FROM THE SECRETING CELL 8 6.01e-01 0.107000 8.94e-01
REACTOME NETRIN 1 SIGNALING 49 6.02e-01 -0.043000 8.95e-01
REACTOME INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE 20 6.03e-01 0.067200 8.95e-01
REACTOME EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION 27 6.04e-01 0.057700 8.96e-01
REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA 11 6.05e-01 -0.090000 8.96e-01
REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS 37 6.07e-01 0.048800 8.96e-01
REACTOME CILIUM ASSEMBLY 190 6.07e-01 0.021600 8.96e-01
REACTOME DAG AND IP3 SIGNALING 40 6.08e-01 0.046900 8.96e-01
REACTOME AMINO ACID CONJUGATION 9 6.08e-01 -0.098600 8.96e-01
REACTOME FORMATION OF PARAXIAL MESODERM 22 6.10e-01 -0.062900 8.96e-01
REACTOME BIOTIN TRANSPORT AND METABOLISM 10 6.10e-01 -0.093300 8.96e-01
REACTOME CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY 25 6.10e-01 0.059000 8.96e-01
REACTOME FCGR ACTIVATION 11 6.10e-01 0.088800 8.96e-01
REACTOME RECYCLING OF BILE ACIDS AND SALTS 18 6.10e-01 0.069400 8.96e-01
REACTOME TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS 36 6.10e-01 0.049100 8.96e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST 18 6.11e-01 0.069200 8.97e-01
REACTOME ACTIVATION OF RAS IN B CELLS 5 6.13e-01 0.131000 8.98e-01
REACTOME TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS 26 6.13e-01 -0.057300 8.98e-01
REACTOME ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS 10 6.14e-01 -0.092200 8.98e-01
REACTOME SCAVENGING BY CLASS F RECEPTORS 6 6.17e-01 0.118000 9.02e-01
REACTOME SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS 43 6.18e-01 0.044000 9.02e-01
REACTOME LIGAND RECEPTOR INTERACTIONS 8 6.18e-01 0.102000 9.02e-01
REACTOME HDMS DEMETHYLATE HISTONES 40 6.18e-01 0.045500 9.02e-01
REACTOME REGULATION OF NPAS4 GENE EXPRESSION 13 6.20e-01 0.079500 9.02e-01
REACTOME NERVOUS SYSTEM DEVELOPMENT 552 6.20e-01 0.012400 9.02e-01
REACTOME DEFECTS IN COBALAMIN B12 METABOLISM 13 6.20e-01 0.079400 9.02e-01
REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR 19 6.21e-01 -0.065500 9.02e-01
REACTOME PINK1 PRKN MEDIATED MITOPHAGY 22 6.21e-01 0.060800 9.02e-01
REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS 11 6.22e-01 0.085900 9.02e-01
REACTOME ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM 12 6.23e-01 0.082000 9.03e-01
REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI 17 6.24e-01 0.068700 9.03e-01
REACTOME HOST INTERACTIONS OF HIV FACTORS 127 6.24e-01 0.025200 9.03e-01
REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION 36 6.25e-01 0.047100 9.03e-01
REACTOME FGFR3 LIGAND BINDING AND ACTIVATION 12 6.25e-01 0.081400 9.03e-01
REACTOME SYNTHESIS OF PE 13 6.26e-01 0.078200 9.03e-01
REACTOME HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR IN THE PRESENCE OF LIGAND 55 6.26e-01 -0.037900 9.03e-01
REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE 20 6.29e-01 0.062400 9.05e-01
REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT 236 6.29e-01 -0.018200 9.05e-01
REACTOME CHOLINE CATABOLISM 6 6.30e-01 -0.113000 9.06e-01
REACTOME HDL CLEARANCE 5 6.31e-01 0.124000 9.07e-01
REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS 21 6.32e-01 0.060400 9.07e-01
REACTOME ESTROGEN DEPENDENT GENE EXPRESSION 140 6.33e-01 0.023400 9.07e-01
REACTOME ERYTHROPOIETIN ACTIVATES STAT5 7 6.34e-01 0.104000 9.07e-01
REACTOME SMALL INTERFERING RNA SIRNA BIOGENESIS 9 6.35e-01 0.091300 9.07e-01
REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE 16 6.35e-01 0.068500 9.07e-01
REACTOME REGULATION OF LIPID METABOLISM BY PPARALPHA 115 6.35e-01 -0.025600 9.07e-01
REACTOME ACTIVATION OF SMO 18 6.36e-01 0.064500 9.07e-01
REACTOME REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION 9 6.36e-01 -0.091000 9.07e-01
REACTOME RETROGRADE NEUROTROPHIN SIGNALLING 14 6.39e-01 0.072400 9.07e-01
REACTOME TYPE I HEMIDESMOSOME ASSEMBLY 11 6.40e-01 -0.081400 9.07e-01
REACTOME RAF INDEPENDENT MAPK1 3 ACTIVATION 22 6.41e-01 -0.057500 9.07e-01
REACTOME TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA 17 6.41e-01 -0.065300 9.07e-01
REACTOME EARLY SARS COV 2 INFECTION EVENTS 34 6.41e-01 -0.046100 9.07e-01
REACTOME LEISHMANIA INFECTION 156 6.42e-01 0.021500 9.07e-01
REACTOME SYNTHESIS OF DOLICHYL PHOSPHATE 6 6.43e-01 -0.109000 9.07e-01
REACTOME SPERM MOTILITY AND TAXES 9 6.43e-01 -0.089100 9.07e-01
REACTOME DNA STRAND ELONGATION 31 6.44e-01 0.048000 9.07e-01
REACTOME MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS 17 6.44e-01 -0.064800 9.07e-01
REACTOME DISEASES OF BASE EXCISION REPAIR 5 6.44e-01 0.119000 9.07e-01
REACTOME NUCLEAR PORE COMPLEX NPC DISASSEMBLY 36 6.44e-01 0.044500 9.07e-01
REACTOME PROCESSING OF SMDT1 16 6.44e-01 -0.066700 9.07e-01
REACTOME CYTOSOLIC TRNA AMINOACYLATION 22 6.45e-01 0.056700 9.07e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL 14 6.45e-01 -0.071000 9.07e-01
REACTOME UPTAKE AND ACTIONS OF BACTERIAL TOXINS 28 6.46e-01 0.050200 9.07e-01
REACTOME COPI MEDIATED ANTEROGRADE TRANSPORT 101 6.46e-01 -0.026500 9.07e-01
REACTOME PEROXISOMAL PROTEIN IMPORT 62 6.46e-01 0.033700 9.07e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR4 14 6.47e-01 0.070800 9.07e-01
REACTOME SYNTHESIS OF GDP MANNOSE 5 6.47e-01 -0.118000 9.07e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES 49 6.47e-01 0.037800 9.07e-01
REACTOME PECAM1 INTERACTIONS 12 6.49e-01 -0.075800 9.09e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS 9 6.50e-01 0.087400 9.09e-01
REACTOME RUNX3 REGULATES BCL2L11 BIM TRANSCRIPTION 5 6.50e-01 0.117000 9.09e-01
REACTOME RORA ACTIVATES GENE EXPRESSION 17 6.51e-01 -0.063300 9.09e-01
REACTOME TRANSPORT OF RCBL WITHIN THE BODY 8 6.51e-01 0.092300 9.09e-01
REACTOME PROCESSING OF INTRONLESS PRE MRNAS 19 6.52e-01 0.059700 9.09e-01
REACTOME NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION 193 6.53e-01 -0.018800 9.09e-01
REACTOME SODIUM CALCIUM EXCHANGERS 11 6.53e-01 -0.078200 9.09e-01
REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE 11 6.55e-01 0.077900 9.09e-01
REACTOME P2Y RECEPTORS 9 6.55e-01 0.086100 9.09e-01
REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION 32 6.56e-01 -0.045400 9.11e-01
REACTOME GLUCOSE METABOLISM 90 6.57e-01 0.027100 9.11e-01
REACTOME PROPIONYL COA CATABOLISM 5 6.57e-01 0.115000 9.11e-01
REACTOME NUCLEAR IMPORT OF REV PROTEIN 34 6.58e-01 0.043800 9.11e-01
REACTOME RUNX3 REGULATES CDKN1A TRANSCRIPTION 7 6.59e-01 -0.096400 9.11e-01
REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING 13 6.60e-01 0.070500 9.12e-01
REACTOME SIGNALING BY NOTCH2 32 6.60e-01 0.044900 9.12e-01
REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF 53 6.61e-01 0.034800 9.12e-01
REACTOME DNA DAMAGE REVERSAL 8 6.62e-01 -0.089200 9.13e-01
REACTOME HSF1 ACTIVATION 29 6.63e-01 0.046800 9.13e-01
REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS 9 6.67e-01 0.082900 9.16e-01
REACTOME TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA 36 6.67e-01 0.041500 9.16e-01
REACTOME METABOLISM OF VITAMINS AND COFACTORS 185 6.67e-01 -0.018300 9.16e-01
REACTOME RECYCLING OF EIF2 GDP 7 6.68e-01 0.093700 9.16e-01
REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS 62 6.68e-01 0.031500 9.16e-01
REACTOME PHYSIOLOGICAL FACTORS 14 6.72e-01 0.065400 9.16e-01
REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN 76 6.73e-01 0.028000 9.16e-01
REACTOME EICOSANOIDS 12 6.73e-01 -0.070500 9.16e-01
REACTOME RHOC GTPASE CYCLE 71 6.73e-01 -0.028900 9.16e-01
REACTOME ACTIVATION OF AMPK DOWNSTREAM OF NMDARS 28 6.74e-01 -0.046000 9.16e-01
REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE 20 6.74e-01 -0.054300 9.16e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG 7 6.75e-01 -0.091600 9.16e-01
REACTOME SIGNAL TRANSDUCTION BY L1 20 6.75e-01 -0.054100 9.16e-01
REACTOME REGULATION OF NPAS4 MRNA TRANSLATION 9 6.75e-01 0.080600 9.16e-01
REACTOME METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS 122 6.76e-01 0.021900 9.16e-01
REACTOME LIPID PARTICLE ORGANIZATION 6 6.76e-01 0.098400 9.16e-01
REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION 62 6.77e-01 0.030600 9.16e-01
REACTOME PLATELET SENSITIZATION BY LDL 17 6.78e-01 -0.058300 9.16e-01
REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE 30 6.78e-01 0.043800 9.16e-01
REACTOME MISMATCH REPAIR 15 6.78e-01 0.061800 9.16e-01
REACTOME SIGNALING BY BMP 27 6.78e-01 0.046100 9.16e-01
REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 44 6.79e-01 0.036100 9.16e-01
REACTOME MRNA EDITING C TO U CONVERSION 8 6.79e-01 0.084500 9.16e-01
REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION 9 6.81e-01 0.079000 9.16e-01
REACTOME ION HOMEOSTASIS 52 6.82e-01 -0.032800 9.16e-01
REACTOME TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE 39 6.83e-01 0.037700 9.16e-01
REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF 17 6.84e-01 0.057000 9.16e-01
REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS 14 6.84e-01 -0.062800 9.16e-01
REACTOME INTERLEUKIN 27 SIGNALING 11 6.85e-01 0.070600 9.16e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX 91 6.85e-01 0.024600 9.16e-01
REACTOME DNA REPLICATION INITIATION 7 6.85e-01 0.088400 9.16e-01
REACTOME HYDROLYSIS OF LPC 9 6.86e-01 -0.077800 9.16e-01
REACTOME TCR SIGNALING 113 6.87e-01 0.021900 9.16e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA 25 6.88e-01 -0.046500 9.16e-01
REACTOME GAP JUNCTION DEGRADATION 12 6.88e-01 0.067000 9.16e-01
REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX 31 6.89e-01 0.041600 9.16e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH CDC42 19 6.89e-01 0.053000 9.16e-01
REACTOME ARACHIDONIC ACID METABOLISM 57 6.89e-01 -0.030600 9.16e-01
REACTOME TELOMERE C STRAND LAGGING STRAND SYNTHESIS 33 6.90e-01 -0.040100 9.16e-01
REACTOME CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA 63 6.91e-01 0.029000 9.16e-01
REACTOME PROTEIN FOLDING 96 6.91e-01 0.023500 9.16e-01
REACTOME ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS 87 6.91e-01 0.024600 9.16e-01
REACTOME TELOMERE EXTENSION BY TELOMERASE 22 6.92e-01 -0.048800 9.16e-01
REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI 26 6.92e-01 0.044800 9.16e-01
REACTOME P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1 6 6.93e-01 -0.093200 9.16e-01
REACTOME PP2A MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS 6 6.93e-01 -0.093000 9.16e-01
REACTOME P75NTR SIGNALS VIA NF KB 15 6.93e-01 0.058800 9.16e-01
REACTOME TIGHT JUNCTION INTERACTIONS 29 6.94e-01 0.042300 9.16e-01
REACTOME REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS 15 6.94e-01 0.058700 9.16e-01
REACTOME RHOG GTPASE CYCLE 71 6.94e-01 0.027000 9.16e-01
REACTOME REGULATION OF IFNG SIGNALING 14 6.94e-01 0.060800 9.16e-01
REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS 33 6.94e-01 0.039600 9.16e-01
REACTOME TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS 43 6.96e-01 0.034500 9.16e-01
REACTOME ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA 5 6.96e-01 -0.101000 9.16e-01
REACTOME NOSTRIN MEDIATED ENOS TRAFFICKING 5 6.97e-01 -0.101000 9.16e-01
REACTOME MISCELLANEOUS TRANSPORT AND BINDING EVENTS 24 6.97e-01 -0.045900 9.16e-01
REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE 24 6.97e-01 -0.045900 9.16e-01
REACTOME ROBO RECEPTORS BIND AKAP5 9 6.98e-01 0.074800 9.16e-01
REACTOME INSULIN PROCESSING 24 6.98e-01 0.045800 9.16e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE 11 6.99e-01 0.067200 9.17e-01
REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX 14 7.00e-01 0.059500 9.17e-01
REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP 41 7.00e-01 -0.034800 9.17e-01
REACTOME POST TRANSCRIPTIONAL SILENCING BY SMALL RNAS 7 7.02e-01 0.083600 9.18e-01
REACTOME CTLA4 INHIBITORY SIGNALING 21 7.03e-01 -0.048000 9.18e-01
REACTOME MEIOTIC SYNAPSIS 73 7.04e-01 0.025700 9.18e-01
REACTOME REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS 7 7.04e-01 0.082800 9.18e-01
REACTOME BASE EXCISION REPAIR AP SITE FORMATION 59 7.04e-01 0.028600 9.18e-01
REACTOME SARS COV 2 ACTIVATES MODULATES INNATE AND ADAPTIVE IMMUNE RESPONSES 118 7.05e-01 0.020200 9.18e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K 12 7.06e-01 -0.062900 9.18e-01
REACTOME REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS 11 7.06e-01 0.065600 9.18e-01
REACTOME HYALURONAN BIOSYNTHESIS AND EXPORT 5 7.06e-01 0.097300 9.18e-01
REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE 17 7.07e-01 0.052600 9.18e-01
REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX 21 7.07e-01 -0.047300 9.18e-01
REACTOME CAMK IV MEDIATED PHOSPHORYLATION OF CREB 10 7.08e-01 0.068400 9.18e-01
REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION 74 7.09e-01 -0.025100 9.18e-01
REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS 13 7.10e-01 0.059500 9.19e-01
REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM 20 7.11e-01 0.047900 9.19e-01
REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES 27 7.14e-01 0.040800 9.20e-01
REACTOME TRIGLYCERIDE METABOLISM 35 7.15e-01 -0.035700 9.20e-01
REACTOME PREDNISONE ADME 10 7.15e-01 0.066600 9.20e-01
REACTOME RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR 19 7.16e-01 0.048200 9.20e-01
REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE 52 7.17e-01 0.029100 9.20e-01
REACTOME FGFR2 LIGAND BINDING AND ACTIVATION 19 7.18e-01 0.047900 9.20e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING 5 7.19e-01 -0.092800 9.20e-01
REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES 38 7.22e-01 -0.033400 9.20e-01
REACTOME SPRY REGULATION OF FGF SIGNALING 16 7.22e-01 0.051400 9.20e-01
REACTOME DEFECTIVE EXT2 CAUSES EXOSTOSES 2 12 7.24e-01 -0.059000 9.20e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FYN 7 7.24e-01 -0.077200 9.20e-01
REACTOME BETA CATENIN INDEPENDENT WNT SIGNALING 145 7.24e-01 0.017000 9.20e-01
REACTOME ACTIVATION OF PPARGC1A PGC 1ALPHA BY PHOSPHORYLATION 10 7.25e-01 0.064300 9.20e-01
REACTOME INTERFERON ALPHA BETA SIGNALING 70 7.26e-01 -0.024200 9.20e-01
REACTOME PI5P REGULATES TP53 ACETYLATION 9 7.26e-01 -0.067400 9.20e-01
REACTOME IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS 17 7.26e-01 -0.049100 9.20e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER 28 7.26e-01 -0.038200 9.20e-01
REACTOME RAC1 GTPASE CYCLE 172 7.27e-01 -0.015500 9.20e-01
REACTOME LIPOPHAGY 9 7.27e-01 -0.067200 9.20e-01
REACTOME MET RECEPTOR ACTIVATION 6 7.27e-01 0.082200 9.20e-01
REACTOME RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES TREGS 9 7.27e-01 -0.067100 9.20e-01
REACTOME BETA CATENIN PHOSPHORYLATION CASCADE 16 7.28e-01 0.050300 9.20e-01
REACTOME DEFECTIVE RIPK1 MEDIATED REGULATED NECROSIS 7 7.29e-01 0.075700 9.20e-01
REACTOME FGFR3B LIGAND BINDING AND ACTIVATION 7 7.29e-01 -0.075600 9.20e-01
REACTOME DEFECTIVE LFNG CAUSES SCDO3 5 7.29e-01 0.089400 9.20e-01
REACTOME MIRO GTPASE CYCLE 8 7.30e-01 -0.070400 9.20e-01
REACTOME ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS 11 7.32e-01 0.059700 9.20e-01
REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT 31 7.32e-01 0.035600 9.20e-01
REACTOME FANCONI ANEMIA PATHWAY 35 7.32e-01 0.033400 9.20e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION 41 7.32e-01 0.030900 9.20e-01
REACTOME MET INTERACTS WITH TNS PROTEINS 5 7.32e-01 -0.088300 9.20e-01
REACTOME SUPPRESSION OF PHAGOSOMAL MATURATION 13 7.33e-01 0.054700 9.20e-01
REACTOME SIGNALING BY PDGF 57 7.33e-01 0.026100 9.20e-01
REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING 13 7.33e-01 0.054600 9.20e-01
REACTOME FGFR2C LIGAND BINDING AND ACTIVATION 12 7.34e-01 0.056600 9.20e-01
REACTOME LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX 5 7.35e-01 -0.087400 9.20e-01
REACTOME KERATAN SULFATE KERATIN METABOLISM 34 7.35e-01 0.033500 9.20e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER 28 7.35e-01 0.037000 9.20e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL 14 7.35e-01 -0.052200 9.20e-01
REACTOME NEF AND SIGNAL TRANSDUCTION 8 7.36e-01 0.068900 9.20e-01
REACTOME RHO GTPASES ACTIVATE WASPS AND WAVES 34 7.36e-01 0.033400 9.20e-01
REACTOME ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT 23 7.36e-01 0.040600 9.20e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN 21 7.37e-01 0.042300 9.20e-01
REACTOME SMAC XIAP REGULATED APOPTOTIC RESPONSE 7 7.38e-01 -0.073100 9.20e-01
REACTOME GABA RECEPTOR ACTIVATION 57 7.38e-01 -0.025600 9.20e-01
REACTOME ATORVASTATIN ADME 9 7.39e-01 -0.064100 9.20e-01
REACTOME LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS 19 7.40e-01 0.043900 9.20e-01
REACTOME UNWINDING OF DNA 12 7.41e-01 0.055100 9.20e-01
REACTOME ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING 9 7.42e-01 -0.063500 9.20e-01
REACTOME FREE FATTY ACIDS REGULATE INSULIN SECRETION 10 7.42e-01 0.060100 9.20e-01
REACTOME CELL JUNCTION ORGANIZATION 89 7.42e-01 -0.020200 9.20e-01
REACTOME ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS 7 7.42e-01 -0.071800 9.20e-01
REACTOME LAGGING STRAND SYNTHESIS 19 7.43e-01 0.043500 9.20e-01
REACTOME SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL 25 7.43e-01 -0.037900 9.20e-01
REACTOME DISEASES OF PROGRAMMED CELL DEATH 96 7.44e-01 0.019300 9.20e-01
REACTOME ALPHA OXIDATION OF PHYTANATE 6 7.44e-01 0.077100 9.20e-01
REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE 52 7.44e-01 0.026200 9.20e-01
REACTOME CONJUGATION OF BENZOATE WITH GLYCINE 6 7.44e-01 -0.076900 9.20e-01
REACTOME POTASSIUM CHANNELS 102 7.44e-01 -0.018700 9.20e-01
REACTOME RHO GTPASE CYCLE 423 7.45e-01 0.009230 9.20e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1 20 7.45e-01 0.042000 9.20e-01
REACTOME RRNA MODIFICATION IN THE MITOCHONDRION 6 7.46e-01 -0.076400 9.20e-01
REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS 16 7.46e-01 0.046800 9.20e-01
REACTOME SIGNALING BY NTRK2 TRKB 25 7.47e-01 0.037200 9.20e-01
REACTOME FCERI MEDIATED MAPK ACTIVATION 32 7.48e-01 0.032800 9.21e-01
REACTOME ABC TRANSPORTER DISORDERS 76 7.49e-01 0.021200 9.22e-01
REACTOME GLUTATHIONE CONJUGATION 33 7.51e-01 0.031900 9.23e-01
REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX 39 7.53e-01 0.029100 9.23e-01
REACTOME CHYLOMICRON ASSEMBLY 10 7.54e-01 0.057300 9.23e-01
REACTOME DISORDERS OF TRANSMEMBRANE TRANSPORTERS 170 7.54e-01 0.014000 9.23e-01
REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC 198 7.55e-01 -0.012800 9.23e-01
REACTOME MINERALOCORTICOID BIOSYNTHESIS 6 7.56e-01 -0.073400 9.23e-01
REACTOME INOSITOL PHOSPHATE METABOLISM 45 7.56e-01 0.026800 9.23e-01
REACTOME CA DEPENDENT EVENTS 36 7.57e-01 0.029800 9.23e-01
REACTOME GLYCOLYSIS 70 7.57e-01 0.021400 9.23e-01
REACTOME RHOA GTPASE CYCLE 142 7.58e-01 -0.015000 9.23e-01
REACTOME LDL CLEARANCE 19 7.58e-01 -0.040800 9.23e-01
REACTOME SIGNALING BY RNF43 MUTANTS 8 7.58e-01 -0.062800 9.23e-01
REACTOME G1 S SPECIFIC TRANSCRIPTION 28 7.59e-01 0.033500 9.23e-01
REACTOME METHIONINE SALVAGE PATHWAY 6 7.59e-01 0.072400 9.23e-01
REACTOME G2 M DNA REPLICATION CHECKPOINT 5 7.59e-01 -0.079200 9.23e-01
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES 255 7.61e-01 -0.011100 9.23e-01
REACTOME GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION 30 7.61e-01 -0.032100 9.23e-01
REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE 15 7.61e-01 0.045400 9.23e-01
REACTOME RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION 22 7.63e-01 -0.037200 9.24e-01
REACTOME NFE2L2 REGULATING ANTI OXIDANT DETOXIFICATION ENZYMES 17 7.63e-01 0.042300 9.24e-01
REACTOME SIGNALING BY MET 78 7.63e-01 -0.019700 9.24e-01
REACTOME RESOLUTION OF ABASIC SITES AP SITES 38 7.64e-01 -0.028200 9.24e-01
REACTOME DISEASES OF CARBOHYDRATE METABOLISM 31 7.64e-01 -0.031200 9.24e-01
REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ 6 7.65e-01 -0.070600 9.24e-01
REACTOME RHOBTB1 GTPASE CYCLE 22 7.66e-01 -0.036600 9.24e-01
REACTOME SIGNALING BY VEGF 102 7.67e-01 0.017000 9.24e-01
REACTOME CHYLOMICRON CLEARANCE 5 7.67e-01 0.076400 9.24e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH METHYLATION 19 7.69e-01 0.038900 9.24e-01
REACTOME O LINKED GLYCOSYLATION OF MUCINS 61 7.69e-01 0.021700 9.24e-01
REACTOME SIGNALING BY MAPK MUTANTS 6 7.70e-01 -0.069100 9.24e-01
REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES 78 7.70e-01 0.019200 9.24e-01
REACTOME RELAXIN RECEPTORS 8 7.71e-01 0.059600 9.24e-01
REACTOME EPHA MEDIATED GROWTH CONE COLLAPSE 29 7.71e-01 0.031200 9.24e-01
REACTOME SYNTHESIS OF LIPOXINS LX 6 7.71e-01 0.068500 9.24e-01
REACTOME UPTAKE AND FUNCTION OF ANTHRAX TOXINS 11 7.71e-01 -0.050600 9.24e-01
REACTOME RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS 9 7.71e-01 0.055900 9.24e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2 13 7.72e-01 -0.046300 9.24e-01
REACTOME EXTENSION OF TELOMERES 49 7.73e-01 -0.023800 9.24e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE 20 7.75e-01 -0.037000 9.26e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY 19 7.75e-01 -0.037800 9.26e-01
REACTOME INTERFERON GAMMA SIGNALING 88 7.76e-01 0.017600 9.26e-01
REACTOME HISTIDINE CATABOLISM 8 7.77e-01 -0.058000 9.26e-01
REACTOME RHOJ GTPASE CYCLE 51 7.77e-01 0.022900 9.26e-01
REACTOME RHOT1 GTPASE CYCLE 5 7.78e-01 0.072600 9.27e-01
REACTOME SARS COV 1 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS 16 7.80e-01 0.040400 9.27e-01
REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS 30 7.80e-01 -0.029500 9.27e-01
REACTOME NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 22 7.80e-01 0.034300 9.27e-01
REACTOME NEGATIVE REGULATION OF MAPK PATHWAY 41 7.82e-01 0.025000 9.27e-01
REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION 15 7.82e-01 0.041300 9.27e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS 34 7.83e-01 -0.027300 9.27e-01
REACTOME PRE NOTCH PROCESSING IN GOLGI 18 7.83e-01 0.037400 9.27e-01
REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE 5 7.83e-01 -0.071000 9.27e-01
REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT 99 7.84e-01 0.015900 9.28e-01
REACTOME G PROTEIN BETA GAMMA SIGNALLING 30 7.86e-01 -0.028700 9.29e-01
REACTOME ENOS ACTIVATION 11 7.88e-01 -0.046900 9.30e-01
REACTOME RRNA PROCESSING IN THE MITOCHONDRION 9 7.88e-01 -0.051800 9.30e-01
REACTOME INTEGRATION OF PROVIRUS 9 7.89e-01 0.051400 9.31e-01
REACTOME CATION COUPLED CHLORIDE COTRANSPORTERS 7 7.91e-01 -0.057900 9.32e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION 29 7.92e-01 -0.028300 9.33e-01
REACTOME NEGATIVE REGULATION OF ACTIVITY OF TFAP2 AP 2 FAMILY TRANSCRIPTION FACTORS 10 7.93e-01 0.048000 9.33e-01
REACTOME DIGESTION OF DIETARY LIPID 7 7.94e-01 -0.057000 9.34e-01
REACTOME ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS 24 7.96e-01 0.030400 9.36e-01
REACTOME GLYCEROPHOSPHOLIPID CATABOLISM 7 7.97e-01 -0.056200 9.36e-01
REACTOME REGULATION BY C FLIP 11 7.97e-01 0.044700 9.36e-01
REACTOME ORGANIC CATION TRANSPORT 10 7.98e-01 0.046700 9.36e-01
REACTOME NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 25 7.99e-01 -0.029400 9.36e-01
REACTOME PREGNENOLONE BIOSYNTHESIS 12 8.00e-01 -0.042200 9.37e-01
REACTOME TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE 20 8.02e-01 -0.032400 9.39e-01
REACTOME RND2 GTPASE CYCLE 42 8.04e-01 0.022200 9.39e-01
REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES 22 8.04e-01 0.030600 9.39e-01
REACTOME NUCLEAR ENVELOPE BREAKDOWN 52 8.05e-01 -0.019800 9.39e-01
REACTOME LATE ENDOSOMAL MICROAUTOPHAGY 33 8.05e-01 0.024800 9.39e-01
REACTOME MITOCHONDRIAL TRNA AMINOACYLATION 20 8.06e-01 0.031800 9.39e-01
REACTOME MYOCLONIC EPILEPSY OF LAFORA 9 8.06e-01 0.047300 9.39e-01
REACTOME HCMV EARLY EVENTS 128 8.07e-01 0.012500 9.40e-01
REACTOME TRANSLESION SYNTHESIS BY POLK 17 8.10e-01 0.033700 9.43e-01
REACTOME RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION 8 8.11e-01 -0.048900 9.43e-01
REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES 21 8.13e-01 -0.029800 9.45e-01
REACTOME NEPHRIN FAMILY INTERACTIONS 22 8.15e-01 -0.028900 9.45e-01
REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS 43 8.15e-01 0.020600 9.45e-01
REACTOME MYOGENESIS 29 8.16e-01 0.024900 9.45e-01
REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES 77 8.16e-01 0.015300 9.45e-01
REACTOME MUSCARINIC ACETYLCHOLINE RECEPTORS 5 8.17e-01 0.059700 9.45e-01
REACTOME SIGNALING BY ALK 26 8.18e-01 0.026000 9.45e-01
REACTOME SCAVENGING OF HEME FROM PLASMA 13 8.20e-01 -0.036400 9.45e-01
REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION 90 8.20e-01 0.013800 9.45e-01
REACTOME SCAVENGING BY CLASS B RECEPTORS 6 8.21e-01 0.053500 9.45e-01
REACTOME SUMOYLATION OF DNA METHYLATION PROTEINS 16 8.21e-01 0.032600 9.45e-01
REACTOME BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA 5 8.22e-01 0.058200 9.45e-01
REACTOME ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS 17 8.22e-01 0.031500 9.45e-01
REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE 22 8.23e-01 -0.027600 9.45e-01
REACTOME EPHB MEDIATED FORWARD SIGNALING 41 8.23e-01 -0.020200 9.45e-01
REACTOME GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION 34 8.23e-01 -0.022100 9.45e-01
REACTOME TRANSLESION SYNTHESIS BY POLH 19 8.23e-01 0.029600 9.45e-01
REACTOME TRANSPORT AND SYNTHESIS OF PAPS 6 8.24e-01 0.052500 9.45e-01
REACTOME PHASE 0 RAPID DEPOLARISATION 31 8.24e-01 -0.023100 9.45e-01
REACTOME TERMINAL PATHWAY OF COMPLEMENT 8 8.24e-01 0.045300 9.45e-01
REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE 17 8.26e-01 -0.030900 9.45e-01
REACTOME REACTIONS SPECIFIC TO THE COMPLEX N GLYCAN SYNTHESIS PATHWAY 10 8.27e-01 -0.040000 9.45e-01
REACTOME SELECTIVE AUTOPHAGY 79 8.27e-01 -0.014200 9.45e-01
REACTOME RHO GTPASES ACTIVATE ROCKS 19 8.27e-01 -0.028900 9.45e-01
REACTOME DEFECTS IN BIOTIN BTN METABOLISM 8 8.27e-01 0.044500 9.45e-01
REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET 8 8.28e-01 0.044500 9.45e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING 5 8.29e-01 -0.055600 9.46e-01
REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS 118 8.30e-01 0.011400 9.47e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS 12 8.33e-01 -0.035100 9.49e-01
REACTOME MITOCHONDRIAL UNCOUPLING 5 8.34e-01 -0.054000 9.49e-01
REACTOME RND3 GTPASE CYCLE 41 8.35e-01 0.018800 9.49e-01
REACTOME DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE 17 8.35e-01 -0.029100 9.49e-01
REACTOME NOTCH HLH TRANSCRIPTION PATHWAY 24 8.36e-01 0.024400 9.49e-01
REACTOME BICARBONATE TRANSPORTERS 10 8.37e-01 -0.037600 9.49e-01
REACTOME REGULATION OF NF KAPPA B SIGNALING 17 8.37e-01 -0.028800 9.49e-01
REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS 11 8.37e-01 0.035800 9.49e-01
REACTOME GLYCOSAMINOGLYCAN METABOLISM 118 8.37e-01 0.011000 9.49e-01
REACTOME DEADENYLATION OF MRNA 25 8.40e-01 0.023400 9.51e-01
REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING 29 8.44e-01 0.021100 9.56e-01
REACTOME STAT3 NUCLEAR EVENTS DOWNSTREAM OF ALK SIGNALING 9 8.45e-01 0.037500 9.56e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS 15 8.46e-01 0.029000 9.56e-01
REACTOME SUMO IS CONJUGATED TO E1 UBA2 SAE1 5 8.47e-01 -0.049900 9.56e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST 14 8.48e-01 0.029600 9.56e-01
REACTOME SIGNALING BY MRAS COMPLEX MUTANTS 7 8.49e-01 0.041600 9.56e-01
REACTOME PROCESSING AND ACTIVATION OF SUMO 10 8.49e-01 0.034800 9.56e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING 25 8.49e-01 -0.021900 9.56e-01
REACTOME PYROPTOSIS 27 8.50e-01 0.021100 9.56e-01
REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 11 8.50e-01 0.032900 9.56e-01
REACTOME PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS 21 8.50e-01 -0.023800 9.56e-01
REACTOME DISINHIBITION OF SNARE FORMATION 5 8.51e-01 -0.048400 9.56e-01
REACTOME HCMV INFECTION 152 8.52e-01 0.008790 9.56e-01
REACTOME FGFR1B LIGAND BINDING AND ACTIVATION 6 8.52e-01 0.044000 9.56e-01
REACTOME DEFECTIVE CHST3 CAUSES SEDCJD 7 8.54e-01 0.040200 9.56e-01
REACTOME NUCLEAR ENVELOPE NE REASSEMBLY 74 8.55e-01 -0.012300 9.56e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2 17 8.55e-01 0.025600 9.56e-01
REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION 26 8.55e-01 0.020700 9.56e-01
REACTOME POTENTIAL THERAPEUTICS FOR SARS 92 8.56e-01 0.010900 9.57e-01
REACTOME ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA 9 8.57e-01 0.034600 9.58e-01
REACTOME FRUCTOSE CATABOLISM 5 8.60e-01 -0.045600 9.59e-01
REACTOME COSTIMULATION BY THE CD28 FAMILY 64 8.60e-01 -0.012700 9.59e-01
REACTOME DNA DAMAGE BYPASS 47 8.61e-01 0.014700 9.60e-01
REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE 19 8.63e-01 -0.022800 9.61e-01
REACTOME RHOBTB GTPASE CYCLE 34 8.64e-01 0.017000 9.61e-01
REACTOME GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION 42 8.65e-01 0.015200 9.62e-01
REACTOME NICOTINATE METABOLISM 31 8.66e-01 -0.017500 9.62e-01
REACTOME NEUROTRANSMITTER CLEARANCE 9 8.66e-01 -0.032500 9.62e-01
REACTOME SUMO IS PROTEOLYTICALLY PROCESSED 6 8.67e-01 -0.039600 9.62e-01
REACTOME FGFR2B LIGAND BINDING AND ACTIVATION 10 8.67e-01 -0.030600 9.62e-01
REACTOME PRE NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM 6 8.69e-01 0.038900 9.63e-01
REACTOME PROTEIN METHYLATION 17 8.69e-01 -0.023100 9.63e-01
REACTOME RESOLUTION OF SISTER CHROMATID COHESION 120 8.70e-01 -0.008630 9.63e-01
REACTOME BETA OXIDATION OF BUTANOYL COA TO ACETYL COA 5 8.71e-01 0.042100 9.63e-01
REACTOME GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION 14 8.72e-01 0.024800 9.64e-01
REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL 12 8.76e-01 0.026100 9.66e-01
REACTOME IRF3 MEDIATED INDUCTION OF TYPE I IFN 13 8.76e-01 -0.025100 9.66e-01
REACTOME SUMOYLATION OF UBIQUITINYLATION PROTEINS 39 8.76e-01 0.014400 9.66e-01
REACTOME SUMOYLATION OF RNA BINDING PROTEINS 47 8.76e-01 0.013200 9.66e-01
REACTOME ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN 13 8.78e-01 0.024500 9.68e-01
REACTOME DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS 19 8.79e-01 -0.020200 9.68e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES 15 8.80e-01 0.022500 9.68e-01
REACTOME SIGNALING BY WNT IN CANCER 32 8.80e-01 -0.015400 9.68e-01
REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX 36 8.81e-01 -0.014400 9.68e-01
REACTOME THYROXINE BIOSYNTHESIS 10 8.82e-01 -0.027200 9.68e-01
REACTOME NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY 6 8.83e-01 -0.034800 9.68e-01
REACTOME MASTL FACILITATES MITOTIC PROGRESSION 10 8.83e-01 -0.027000 9.68e-01
REACTOME CD209 DC SIGN SIGNALING 20 8.85e-01 0.018700 9.69e-01
REACTOME KSRP KHSRP BINDS AND DESTABILIZES MRNA 17 8.85e-01 0.020200 9.69e-01
REACTOME MATURATION OF SARS COV 2 NUCLEOPROTEIN 15 8.87e-01 0.021300 9.69e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE 74 8.87e-01 -0.009550 9.69e-01
REACTOME RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX 29 8.87e-01 -0.015200 9.69e-01
REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES 91 8.89e-01 0.008500 9.69e-01
REACTOME MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS 7 8.89e-01 -0.030600 9.69e-01
REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM 45 8.89e-01 0.012000 9.69e-01
REACTOME SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA PHE 6 8.90e-01 -0.032700 9.69e-01
REACTOME TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS 82 8.90e-01 0.008820 9.69e-01
REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC 26 8.91e-01 -0.015600 9.69e-01
REACTOME OTHER INTERLEUKIN SIGNALING 24 8.91e-01 0.016200 9.69e-01
REACTOME RNA POLYMERASE III CHAIN ELONGATION 18 8.91e-01 0.018700 9.69e-01
REACTOME SLC TRANSPORTER DISORDERS 94 8.94e-01 0.007990 9.69e-01
REACTOME OTHER SEMAPHORIN INTERACTIONS 18 8.94e-01 0.018200 9.69e-01
REACTOME NETRIN MEDIATED REPULSION SIGNALS 8 8.94e-01 0.027300 9.69e-01
REACTOME CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION 24 8.94e-01 -0.015700 9.69e-01
REACTOME SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS 74 8.94e-01 0.008950 9.69e-01
REACTOME ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS 20 8.95e-01 0.017000 9.70e-01
REACTOME SIGNALING BY HIPPO 19 8.96e-01 -0.017400 9.70e-01
REACTOME DRUG MEDIATED INHIBITION OF CDK4 CDK6 ACTIVITY 5 8.98e-01 -0.033200 9.71e-01
REACTOME METABOLISM OF INGESTED SEMET SEC MESEC INTO H2SE 7 8.99e-01 -0.027800 9.71e-01
REACTOME METABOLISM OF AMINE DERIVED HORMONES 17 8.99e-01 -0.017800 9.71e-01
REACTOME INTERLEUKIN 6 SIGNALING 11 9.00e-01 0.021900 9.71e-01
REACTOME STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES 16 9.00e-01 0.018200 9.71e-01
REACTOME DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS 14 9.01e-01 -0.019200 9.71e-01
REACTOME INTERLEUKIN 6 FAMILY SIGNALING 24 9.02e-01 0.014500 9.72e-01
REACTOME PLATELET HOMEOSTASIS 85 9.03e-01 -0.007620 9.73e-01
REACTOME SIGNALING BY NTRK3 TRKC 17 9.05e-01 0.016700 9.73e-01
REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS 91 9.07e-01 -0.007120 9.73e-01
REACTOME FIBRONECTIN MATRIX FORMATION 6 9.07e-01 0.027700 9.73e-01
REACTOME INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL 14 9.07e-01 0.018000 9.73e-01
REACTOME ACTIVATION OF RAC1 12 9.08e-01 -0.019300 9.73e-01
REACTOME BASE EXCISION REPAIR 87 9.08e-01 -0.007160 9.73e-01
REACTOME CD28 DEPENDENT PI3K AKT SIGNALING 22 9.09e-01 -0.014100 9.73e-01
REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL 41 9.10e-01 0.010200 9.73e-01
REACTOME BASIGIN INTERACTIONS 24 9.11e-01 -0.013200 9.73e-01
REACTOME UREA CYCLE 9 9.11e-01 -0.021500 9.73e-01
REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY 29 9.11e-01 0.012000 9.73e-01
REACTOME MITOCHONDRIAL CALCIUM ION TRANSPORT 23 9.11e-01 -0.013400 9.73e-01
REACTOME ALPHA DEFENSINS 6 9.12e-01 0.026100 9.73e-01
REACTOME INTERLEUKIN 17 SIGNALING 66 9.12e-01 0.007830 9.74e-01
REACTOME TELOMERE C STRAND SYNTHESIS INITIATION 12 9.14e-01 0.018000 9.75e-01
REACTOME MAPK3 ERK1 ACTIVATION 10 9.17e-01 0.019000 9.76e-01
REACTOME SYNTHESIS OF UDP N ACETYL GLUCOSAMINE 7 9.17e-01 0.022700 9.76e-01
REACTOME METABOLISM OF FOLATE AND PTERINES 17 9.18e-01 -0.014400 9.76e-01
REACTOME TRANSCRIPTIONAL REGULATION BY VENTX 41 9.18e-01 0.009290 9.76e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM 38 9.19e-01 -0.009550 9.76e-01
REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4 33 9.19e-01 -0.010200 9.76e-01
REACTOME NEUROTOXICITY OF CLOSTRIDIUM TOXINS 10 9.19e-01 0.018500 9.76e-01
REACTOME SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS 14 9.21e-01 0.015300 9.77e-01
REACTOME CELL CELL COMMUNICATION 126 9.22e-01 -0.005030 9.77e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS 14 9.22e-01 -0.015000 9.77e-01
REACTOME HEME DEGRADATION 15 9.23e-01 -0.014400 9.77e-01
REACTOME INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING 103 9.24e-01 0.005410 9.77e-01
REACTOME MAPK1 ERK2 ACTIVATION 9 9.26e-01 -0.017900 9.77e-01
REACTOME ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS 41 9.26e-01 0.008360 9.77e-01
REACTOME PHASE 2 PLATEAU PHASE 14 9.26e-01 0.014200 9.77e-01
REACTOME INITIATION OF NUCLEAR ENVELOPE NE REFORMATION 18 9.27e-01 -0.012500 9.77e-01
REACTOME MOLYBDENUM COFACTOR BIOSYNTHESIS 6 9.27e-01 -0.021700 9.77e-01
REACTOME CIPROFLOXACIN ADME 5 9.28e-01 -0.023400 9.78e-01
REACTOME REGULATION OF FZD BY UBIQUITINATION 21 9.29e-01 0.011200 9.78e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD4 15 9.31e-01 0.012900 9.79e-01
REACTOME OAS ANTIVIRAL RESPONSE 8 9.31e-01 -0.017600 9.79e-01
REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER 49 9.31e-01 0.007110 9.79e-01
REACTOME PI3K AKT ACTIVATION 9 9.32e-01 0.016400 9.79e-01
REACTOME GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER 25 9.32e-01 0.009810 9.79e-01
REACTOME CA2 ACTIVATED K CHANNELS 9 9.33e-01 0.016100 9.79e-01
REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN 32 9.35e-01 -0.008280 9.79e-01
REACTOME REGULATION OF RUNX1 EXPRESSION AND ACTIVITY 17 9.36e-01 0.011300 9.79e-01
REACTOME DISEASES OF MISMATCH REPAIR MMR 5 9.36e-01 0.020600 9.79e-01
REACTOME LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME 11 9.37e-01 0.013800 9.79e-01
REACTOME EARLY PHASE OF HIV LIFE CYCLE 14 9.38e-01 0.012100 9.79e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS 9 9.38e-01 0.015000 9.79e-01
REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS 35 9.38e-01 0.007600 9.79e-01
REACTOME ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY 10 9.38e-01 0.014100 9.79e-01
REACTOME ADHERENS JUNCTIONS INTERACTIONS 33 9.39e-01 0.007680 9.80e-01
REACTOME PHASE 1 INACTIVATION OF FAST NA CHANNELS 6 9.42e-01 0.017200 9.82e-01
REACTOME DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B 7 9.42e-01 0.015800 9.82e-01
REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN 19 9.45e-01 -0.009130 9.84e-01
REACTOME INTERLEUKIN 37 SIGNALING 20 9.46e-01 0.008790 9.84e-01
REACTOME TRIGLYCERIDE CATABOLISM 23 9.46e-01 -0.008190 9.84e-01
REACTOME PENTOSE PHOSPHATE PATHWAY 12 9.48e-01 0.011000 9.84e-01
REACTOME SENSORY PERCEPTION OF SALTY TASTE 6 9.48e-01 0.015500 9.84e-01
REACTOME REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM 11 9.48e-01 -0.011300 9.84e-01
REACTOME PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR 21 9.49e-01 -0.008110 9.84e-01
REACTOME CHL1 INTERACTIONS 9 9.49e-01 -0.012300 9.84e-01
REACTOME KERATAN SULFATE BIOSYNTHESIS 28 9.52e-01 0.006560 9.86e-01
REACTOME RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION 6 9.52e-01 -0.014000 9.86e-01
REACTOME INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS 37 9.55e-01 0.005380 9.88e-01
REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL 58 9.56e-01 0.004160 9.89e-01
REACTOME APOPTOTIC FACTOR MEDIATED RESPONSE 19 9.58e-01 -0.006960 9.89e-01
REACTOME RESPONSE OF MTB TO PHAGOCYTOSIS 22 9.58e-01 0.006450 9.89e-01
REACTOME CELL CELL JUNCTION ORGANIZATION 64 9.59e-01 -0.003690 9.89e-01
REACTOME METABOLISM OF STEROIDS 150 9.59e-01 -0.002410 9.89e-01
REACTOME INTERLEUKIN 35 SIGNALLING 12 9.60e-01 0.008310 9.90e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL 24 9.62e-01 -0.005670 9.90e-01
REACTOME FERTILIZATION 26 9.62e-01 -0.005350 9.90e-01
REACTOME NS1 MEDIATED EFFECTS ON HOST PATHWAYS 41 9.62e-01 -0.004260 9.90e-01
REACTOME G ALPHA Z SIGNALLING EVENTS 48 9.63e-01 -0.003920 9.90e-01
REACTOME SUMO IS TRANSFERRED FROM E1 TO E2 UBE2I UBC9 7 9.64e-01 0.009750 9.90e-01
REACTOME EFFECTS OF PIP2 HYDROLYSIS 26 9.66e-01 0.004860 9.90e-01
REACTOME SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER 54 9.66e-01 0.003370 9.90e-01
REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION 6 9.66e-01 -0.010100 9.90e-01
REACTOME VITAMIN B1 THIAMIN METABOLISM 5 9.67e-01 -0.010800 9.90e-01
REACTOME SIGNAL ATTENUATION 10 9.68e-01 0.007400 9.90e-01
REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS 38 9.68e-01 0.003770 9.90e-01
REACTOME BETA OXIDATION OF PRISTANOYL COA 9 9.68e-01 0.007750 9.90e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS 11 9.69e-01 -0.006840 9.90e-01
REACTOMEMATURATION OF SARS COV 1 NUCLEOPROTEIN 11 9.71e-01 -0.006270 9.92e-01
REACTOME REGULATION OF PTEN MRNA TRANSLATION 9 9.71e-01 -0.006880 9.92e-01
REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION 10 9.73e-01 0.006260 9.93e-01
REACTOME FCGR3A MEDIATED IL10 SYNTHESIS 36 9.73e-01 0.003210 9.93e-01
REACTOME PKMTS METHYLATE HISTONE LYSINES 64 9.74e-01 -0.002320 9.93e-01
REACTOME LINOLEIC ACID LA METABOLISM 7 9.75e-01 -0.006920 9.93e-01
REACTOME CGMP EFFECTS 16 9.78e-01 -0.003960 9.96e-01
REACTOME SIGNALING BY NOTCH1 69 9.80e-01 -0.001710 9.96e-01
REACTOME SUMOYLATION OF SUMOYLATION PROTEINS 35 9.81e-01 -0.002330 9.96e-01
REACTOME RHO GTPASES ACTIVATE FORMINS 136 9.82e-01 -0.001150 9.96e-01
REACTOME APEX1 INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY 7 9.82e-01 -0.005040 9.96e-01
REACTOME COBALAMIN CBL METABOLISM 7 9.82e-01 -0.004900 9.96e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS 15 9.83e-01 0.003270 9.96e-01
REACTOME TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX 14 9.84e-01 -0.003160 9.96e-01
REACTOME ESTABLISHMENT OF SISTER CHROMATID COHESION 9 9.84e-01 0.003850 9.96e-01
REACTOME ABACAVIR ADME 9 9.84e-01 0.003830 9.96e-01
REACTOME BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA 5 9.85e-01 0.004980 9.96e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING 6 9.87e-01 0.003860 9.97e-01
REACTOME RHOV GTPASE CYCLE 36 9.88e-01 0.001450 9.97e-01
REACTOME STRIATED MUSCLE CONTRACTION 35 9.89e-01 0.001330 9.97e-01
REACTOME CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION 11 9.89e-01 -0.002310 9.97e-01
REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE 48 9.90e-01 -0.001100 9.97e-01
REACTOME ARYL HYDROCARBON RECEPTOR SIGNALLING 6 9.90e-01 -0.003060 9.97e-01
REACTOME HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS 7 9.91e-01 0.002580 9.97e-01
REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS 19 9.91e-01 -0.001570 9.97e-01
REACTOME SARS COV 2 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS 12 9.91e-01 0.001800 9.97e-01
REACTOME PYRUVATE METABOLISM 29 9.93e-01 -0.000919 9.97e-01
REACTOME POLO LIKE KINASE MEDIATED EVENTS 16 9.94e-01 0.001160 9.97e-01
REACTOME PTK6 REGULATES CELL CYCLE 6 9.95e-01 0.001530 9.97e-01
REACTOME EPH EPHRIN SIGNALING 90 9.95e-01 0.000391 9.97e-01
REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS 23 9.95e-01 -0.000744 9.97e-01
REACTOME POLYMERASE SWITCHING 13 9.95e-01 0.000972 9.97e-01
REACTOME SIGNALLING TO P38 VIA RIT AND RIN 5 9.96e-01 0.001380 9.97e-01
REACTOME FRUCTOSE METABOLISM 7 9.96e-01 -0.001080 9.97e-01
REACTOME BILE ACID AND BILE SALT METABOLISM 45 9.97e-01 0.000366 9.97e-01
REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE 71 9.97e-01 -0.000263 9.97e-01


Detailed Gene set reports



REACTOME_SENSORY_PERCEPTION

REACTOME_SENSORY_PERCEPTION
1581
set REACTOME_SENSORY_PERCEPTION
setSize 555
pANOVA 1.19e-18
s.dist -0.219
p.adjustANOVA 1.96e-15



Top enriched genes

Top 20 genes
GeneID Gene Rank
OR51I2 -10777
OR5H1 -10756
RBP3 -10727
OR10J3 -10690
RHO -10685
OR8B8 -10683
OR5AK2 -10636
OR2Y1 -10599
OR52H1 -10590
AKR1B10 -10578
OR11L1 -10575
OR8I2 -10558
OR8J1 -10522
OR10G7 -10505
OR2V1 -10460
OR8B4 -10458
OR10C1 -10451
OR52J3 -10420
OR7D4 -10409
OR10Z1 -10404

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
OR51I2 -10777.0
OR5H1 -10756.0
RBP3 -10727.0
OR10J3 -10690.0
RHO -10685.0
OR8B8 -10683.0
OR5AK2 -10636.0
OR2Y1 -10599.0
OR52H1 -10590.0
AKR1B10 -10578.0
OR11L1 -10575.0
OR8I2 -10558.0
OR8J1 -10522.0
OR10G7 -10505.0
OR2V1 -10460.0
OR8B4 -10458.0
OR10C1 -10451.0
OR52J3 -10420.0
OR7D4 -10409.0
OR10Z1 -10404.0
OR4C16 -10385.0
OR56A1 -10328.0
OR2M4 -10300.0
OR1Q1 -10298.0
OR2F1 -10256.0
OR4D11 -10245.0
OR6Y1 -10215.0
APOA4 -10210.0
OR1L8 -10206.0
OR6C75 -10156.0
RTP2 -10140.0
OR51E1 -10134.0
OR11A1 -10126.0
OTOP1 -10125.0
OR51D1 -10111.0
OR2A2 -10102.0
OR6X1 -10075.0
OR4D6 -10064.0
GPIHBP1 -10056.0
OR6C68 -10030.0
OR5C1 -10029.0
OR4F15 -10024.0
OR10K1 -10022.0
OR6C1 -10004.0
OR5B2 -10001.0
OR5M8 -9994.0
OR2AG2 -9978.0
OR8B2 -9975.0
OR52E6 -9971.0
OR10K2 -9951.0
TAS2R39 -9949.0
OR10X1 -9922.0
OR7C1 -9919.0
OR10G8 -9908.0
CNGA4 -9896.0
OR5M11 -9892.0
CHRNA10 -9891.0
OR10Q1 -9864.0
OR1J2 -9858.0
OR2F2 -9852.0
OR10S1 -9847.0
OR10AD1 -9839.0
OR4D5 -9838.0
OR51S1 -9819.0
OR5AC2 -9776.0
OR3A1 -9762.0
OR2W3 -9758.0
HSPG2 -9741.0
TAS2R1 -9728.0
OR52B6 -9689.0
CABP2 -9674.0
TAS2R20 -9665.0
OR2V2 -9655.0
OR2B6 -9641.0
OR5B21 -9640.0
OR5F1 -9630.0
OR13D1 -9622.0
RLBP1 -9618.0
OR2C3 -9593.0
OR13G1 -9540.0
OR7A10 -9470.0
OR5AN1 -9452.0
OR10A3 -9437.0
GNB3 -9414.0
OR2G3 -9411.0
GNGT1 -9405.0
OR8A1 -9392.0
OR7A17 -9366.0
OR10G4 -9343.0
USH1C -9334.0
OR1J1 -9321.0
OR56A3 -9318.0
OR8K3 -9291.0
OR52W1 -9174.0
OR10G2 -9159.0
OR6K2 -9153.0
OR1N1 -9150.0
TAS2R4 -9148.0
OR4M1 -9138.0
OR6V1 -9092.0
MYO15A -9074.0
OR10A7 -9064.0
OR56B1 -9052.0
OR13C3 -9050.0
OR10V1 -8990.0
OR51A7 -8978.0
OR51I1 -8943.0
AKR1C4 -8936.0
OR5K1 -8930.0
OR10A4 -8928.0
OR4E2 -8907.0
OR4K5 -8898.0
OR6N1 -8792.0
OR2AP1 -8732.0
CLPS -8717.0
OPN1SW -8708.0
OR4C12 -8700.0
OR2L2 -8684.0
CNGB1 -8680.0
OR4C45 -8665.0
OR6P1 -8660.0
OR5H15 -8585.0
OR6N2 -8583.0
OR2D3 -8553.0
OR13F1 -8537.0
GNAT3 -8522.0
KCNJ2 -8501.0
OR51B4 -8490.0
OR5K2 -8484.0
OTOF -8467.0
OR52R1 -8465.0
AKR1C3 -8456.0
OR8H1 -8448.5
ITPR3 -8429.0
OR6T1 -8397.0
PDE6B -8393.0
OR1G1 -8383.0
OR5K3 -8361.0
OR10A5 -8328.0
OR4C6 -8280.0
TAS2R5 -8252.0
CTBP2 -8196.0
OR6K6 -8127.0
OR10G9 -8121.0
RDH11 -8089.0
OR6C65 -8071.0
OR5M1 -8048.0
OTOG -8034.0
TAS2R50 -8024.0
OR2T12 -7996.0
BCO1 -7910.0
OR2T1 -7869.0
SPTAN1 -7825.0
CIB2 -7795.0
BSN -7790.0
OR2B11 -7736.0
APOC3 -7735.0
OR5M9 -7722.0
OR5T2 -7719.0
OR5K4 -7678.0
GRK7 -7629.0
OR5L2 -7623.0
OR8J3 -7619.0
OR7G2 -7520.0
GPC1 -7493.0
OR2M3 -7482.0
LRP1 -7472.0
CNGA1 -7427.0
RBP2 -7399.0
OR7A5 -7368.0
OR51M1 -7307.0
STRC -7283.0
OR5T3 -7252.0
EPB41L1 -7218.0
GRXCR2 -7208.0
CAPZB -7190.0
OR52I2 -7150.0
ANO2 -7144.0
TRPM5 -7142.0
OR8U1 -7140.0
GRM4 -7117.0
OR10T2 -7116.0
OR1B1 -7095.0
TAS2R8 -7092.0
LRP10 -7034.0
RDH16 -6973.0
OR8S1 -6967.0
OR13A1 -6945.0
RTP1 -6908.0
OR2S2 -6866.0
OR2L8 -6828.0
OR2Z1 -6826.0
OR4C3 -6722.0
SNAP25 -6716.0
OR5B12 -6624.0
OR8K5 -6599.0
OR2AG1 -6579.0
OR10A6 -6542.0
CHRNA9 -6512.0
AGRN -6505.0
SDR9C7 -6383.0
TAS2R30 -6359.0
CACNA2D2 -6298.0
OR8D2 -6264.0
ATP2B2 -6208.0
TAS1R1 -6199.0
OR1L6 -6188.0
OR51B2 -6172.0
OR5J2 -6131.0
PLB1 -6123.0
OR5W2 -6083.0
OR51E2 -6074.0
CALHM1 -6045.0
CAPZA2 -6028.0
OR5A1 -6016.0
OR14A16 -6009.0
OR10J1 -6007.0
OR4K1 -5993.0
OR5D18 -5969.0
OR2AT4 -5942.0
TTR -5794.0
RDH12 -5758.0
OR52D1 -5733.0
OR4D1 -5728.0
CYP4V2 -5659.0
OR2L13 -5656.0
LRP12 -5633.0
OR7D2 -5625.0
OR5P2 -5607.0
GRK1 -5591.0
OR52K1 -5551.0
CACNA1D -5545.0
OR14I1 -5474.0
OR2H2 -5435.0
OR6C74 -5418.0
TAS2R14 -5369.0
OR51B6 -5356.0
OR1M1 -5342.0
VAMP2 -5341.0
LDLR -5273.0
OR51L1 -5269.0
OR4X2 -5264.0
EPB41L3 -5262.0
SCN9A -5229.0
LRP8 -5192.0
KCNMA1 -5126.0
MYO3A -5051.0
TAS2R31 -5038.0
OR1A2 -4943.0
OR1D2 -4940.0
OR5M10 -4923.0
ACTG1 -4906.0
OR2K2 -4905.0
STRA6 -4837.0
SCNN1G -4728.0
OR1L4 -4686.0
SDC1 -4653.0
EPS8 -4581.0
KCNQ4 -4513.0
GUCA1A -4319.0
OR6K3 -4201.0
OR6C76 -4178.0
OR5I1 -4142.0
OR4A15 -4079.0
PCDH15 -3959.0
OR5L1 -3940.5
SLC26A5 -3889.0
TAS1R2 -3864.0
OR7C2 -3841.0
CACNB2 -3840.0
OR9A2 -3741.0
OR2J2 -3615.0
OR11H6 -3608.0
ABCA4 -3573.0
OR2L5 -3566.0
OR2A12 -3535.0
OR10H1 -3533.0
OR1S2 -3495.0
SCNN1B -3416.0
OR10H5 -3405.0
OR4D10 -3387.0
OR4K17 -3386.0
OR5AS1 -3372.0
SDC2 -3334.0
OR8D1 -3295.0
MYO7A -3290.0
OR51G1 -3279.0
OR7G3 -3267.0
OR51F1 -3260.0
ADCY3 -3259.0
GUCA1B -3198.0
OR10H3 -3160.0
CABP1 -3138.0
ATP2B1 -2961.0
TAS2R46 -2775.0
SLC24A1 -2588.0
NMT1 -2584.0
OR51V1 -2555.0
OR2AE1 -2547.0
FNTA -2544.0
OR6C4 -2539.0
OR1L3 -2440.0
MYH9 -2391.0
PCLO -2383.0
SDC4 -2326.0
PRKCQ -2320.0
OR52L1 -2312.0
METAP1 -2250.0
TRPM4 -2240.0
OR52E4 -2143.0
APOB -2139.0
CLIC5 -2126.0
CDH23 -2097.0
OR9Q2 -2015.0
TMC1 -1930.0
OR51Q1 -1896.0
REEP1 -1863.0
OR10A2 -1820.0
TWF2 -1737.0
OR2T4 -1718.0
APOA2 -1626.0
ACTB -1544.0
TWF1 -1542.0
TAS2R41 -1467.0
PDE6G -1427.0
OR5V1 -1387.0
TAS2R3 -1385.0
OR6A2 -1277.0
OR10H2 -1250.0
RBP4 -1246.0
OR1I1 -1228.0
GUCY2D -1175.0
OR51G2 -1133.0
OR6C3 -1114.0
PJVK -1096.0
GPC6 -1036.0
OR4A5 -1018.0
PRKCA -1005.0
OR2W1 -996.0
OR1K1 -984.0
OR4L1 -881.0
OR1C1 -857.0
RAB3A -844.0
OR51B5 -823.0
MYO1C -819.0
OR8H3 -788.0
OR4S1 -668.0
TMC2 -577.0
OR6B3 -510.0
OR52M1 -501.0
OTOGL -489.0
SCN3A -342.0
TMIE -339.0
TAS2R7 -236.0
TPRN -170.0
GUCA1C -128.0
TAS1R3 -95.0
NAPEPLD -86.0
OR4K14 -45.0
MYO3B 53.0
PLS1 212.0
XIRP2 225.0
OR5P3 247.0
FNTB 293.0
OR8K1 295.0
OR2G6 347.0
APOC2 369.0
OR3A3 393.0
OR2H1 479.0
RPE65 579.0
EBF1 585.0
DHRS3 631.0
OR1N2 635.0
OR2B2 682.0
AKR1C1 687.0
OR6C70 745.0
ESPNL 747.0
PNLIP 754.0
OR8G1 868.0
OR13C8 909.0
LRP2 968.0
TAS2R40 971.0
OR13C9 1153.0
GNAL 1183.0
OR8U8 1199.0
OR1S1 1262.0
RDH5 1292.0
RCVRN 1405.0
RDH8 1419.0
APOA1 1486.0
OR13C2 1554.0
OR6F1 1664.0
OR9K2 1681.0
RIPOR2 1762.0
OR5B17 1868.0
GRM1 1889.0
GNB1 1983.0
OR6C2 2139.0
BCO2 2235.0
CAMKMT 2247.0
RDX 2261.0
OR14J1 2413.0
TAS2R43 2443.0
CALHM3 2523.0
DNAJC5 2571.0
GNAT1 2651.0
OR6S1 2664.0
OR52A1 2691.0
OR51T1 2797.0
GRK4 2976.0
RBP1 3022.0
OR6M1 3089.0
OR1F1 3100.0
OR10H4 3128.0
RGS9 3180.0
CAPZA1 3188.0
OR52N1 3218.0
OR10G3 3268.0
OR56A5 3369.0
OR52E8 3609.0
SCN2B 3779.0
OR7G1 3785.0
OR1A1 3833.0
EZR 3844.0
OR11G2 3853.0
OR7E24 3904.0
TRIOBP 4063.0
PLCB2 4089.0
OR8D4 4145.0
GPC5 4518.0
NMT2 4585.0
KCNMB1 4679.0
OR5B3 4717.0
GRXCR1 4725.0
CALM1 4775.0
OR2B3 5032.0
SCNN1D 5049.0
GNG13 5069.0
OR9G1 5083.5
OR9G9 5083.5
OR8U3 5158.0
RDH10 5237.0
OR4X1 5281.0
METAP2 5316.0
OR52A5 5322.0
TAS2R38 5364.0
OR2G2 5374.0
OR56B4 5452.0
SPTBN1 5461.0
OR51F2 5561.0
OR6B2 5588.0
OR4B1 5711.0
OR52N2 5830.0
OR1E1 5862.0
OR56A4 5865.0
HSD17B1 5894.0
GPC2 6115.0
OR4N2 6116.0
SLC17A8 6158.0
OR2AK2 6268.0
OR4C15 6288.0
OR9A4 6299.0
HSD17B6 6362.0
GNB5 6406.0
OR5AR1 6516.0
OR2C1 6581.0
APOE 6788.0
OR52B2 6880.0
OR5H6 6895.0
OR52I1 6917.0
OR4A16 6970.0
OR2T8 6975.0
LRAT 6987.0
OR1L1 7032.0
OR5AP2 7038.0
OR5H2 7063.0
SCN2A 7064.0
OR2T6 7077.0
RGS9BP 7078.0
ESPN 7141.0
OR12D2 7150.0
SAG 7158.0
SCN1B 7163.0
OR2M5 7167.0
OR2A5 7335.0
RETSAT 7361.0
SCN4B 7466.0
OR2D2 7488.0
WHRN 7811.0
OR9I1 7824.0
LDB1 7864.0
OR2T27 7875.0
STX1A 7920.0
TAS2R10 7922.0
LHFPL5 7956.0
OR11H4 7966.0
OR2M2 7970.0
KCNN2 8123.0
PDE6A 8154.0
OR9Q1 8227.0
OR4A47 8310.0
OR2L3 8342.0
LRRC52 8364.0
OR4K2 8378.0
OR4K15 8427.0
APOM 8446.0
LPL 8455.0
OR10J5 8485.0
SDC3 8535.0
SCNN1A 8621.0
OR5D16 8649.0
OR4D2 8653.0
OR2A14 8678.0
OR14C36 8718.0
OR5D14 8759.0
OR12D3 8860.0
LHX2 8901.0
OR52K2 9001.0
OR4F6 9038.0
TAS2R16 9045.0
OR13J1 9069.0
OR8B12 9087.0
OR2T33 9153.0
OR5T1 9213.0
OR9G4 9244.0
OR8G5 9276.0
OR51A2 9441.0
EPS8L2 9469.0
OR1J4 9545.0
OR13C4 9590.0
OR5AU1 9634.0
OR4D9 9828.0
OR4N5 9881.0
OR1E2 9936.0
OR10AG1 10088.0
USH1G 10093.0
OR5M3 10124.0
OR10P1 10144.0
OR5D13 10180.0
OR2T11 10202.0
OR6B1 10217.0
OR4C46 10238.0
OR10W1 10302.0
FSCN2 10435.0
OR2M7 10445.0
DHRS9 10475.0
OR3A2 10596.0
GSN 10627.0
OR52E2 10725.0
TAS2R13 10869.0
OR4K13 10886.0
OR5A2 10941.0
OR2T3 10976.0
OR6Q1 11015.0
OR6C6 11128.0


REACTOME_OLFACTORY_SIGNALING_PATHWAY

REACTOME_OLFACTORY_SIGNALING_PATHWAY
628
set REACTOME_OLFACTORY_SIGNALING_PATHWAY
setSize 348
pANOVA 3.54e-15
s.dist -0.245
p.adjustANOVA 2.91e-12



Top enriched genes

Top 20 genes
GeneID Gene Rank
OR51I2 -10777
OR5H1 -10756
OR10J3 -10690
OR8B8 -10683
OR5AK2 -10636
OR2Y1 -10599
OR52H1 -10590
OR11L1 -10575
OR8I2 -10558
OR8J1 -10522
OR10G7 -10505
OR2V1 -10460
OR8B4 -10458
OR10C1 -10451
OR52J3 -10420
OR7D4 -10409
OR10Z1 -10404
OR4C16 -10385
OR56A1 -10328
OR2M4 -10300

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
OR51I2 -10777.0
OR5H1 -10756.0
OR10J3 -10690.0
OR8B8 -10683.0
OR5AK2 -10636.0
OR2Y1 -10599.0
OR52H1 -10590.0
OR11L1 -10575.0
OR8I2 -10558.0
OR8J1 -10522.0
OR10G7 -10505.0
OR2V1 -10460.0
OR8B4 -10458.0
OR10C1 -10451.0
OR52J3 -10420.0
OR7D4 -10409.0
OR10Z1 -10404.0
OR4C16 -10385.0
OR56A1 -10328.0
OR2M4 -10300.0
OR1Q1 -10298.0
OR2F1 -10256.0
OR4D11 -10245.0
OR6Y1 -10215.0
OR1L8 -10206.0
OR6C75 -10156.0
RTP2 -10140.0
OR51E1 -10134.0
OR11A1 -10126.0
OR51D1 -10111.0
OR2A2 -10102.0
OR6X1 -10075.0
OR4D6 -10064.0
OR6C68 -10030.0
OR5C1 -10029.0
OR4F15 -10024.0
OR10K1 -10022.0
OR6C1 -10004.0
OR5B2 -10001.0
OR5M8 -9994.0
OR2AG2 -9978.0
OR8B2 -9975.0
OR52E6 -9971.0
OR10K2 -9951.0
OR10X1 -9922.0
OR7C1 -9919.0
OR10G8 -9908.0
CNGA4 -9896.0
OR5M11 -9892.0
OR10Q1 -9864.0
OR1J2 -9858.0
OR2F2 -9852.0
OR10S1 -9847.0
OR10AD1 -9839.0
OR4D5 -9838.0
OR51S1 -9819.0
OR5AC2 -9776.0
OR3A1 -9762.0
OR2W3 -9758.0
OR52B6 -9689.0
OR2V2 -9655.0
OR2B6 -9641.0
OR5B21 -9640.0
OR5F1 -9630.0
OR13D1 -9622.0
OR2C3 -9593.0
OR13G1 -9540.0
OR7A10 -9470.0
OR5AN1 -9452.0
OR10A3 -9437.0
OR2G3 -9411.0
OR8A1 -9392.0
OR7A17 -9366.0
OR10G4 -9343.0
OR1J1 -9321.0
OR56A3 -9318.0
OR8K3 -9291.0
OR52W1 -9174.0
OR10G2 -9159.0
OR6K2 -9153.0
OR1N1 -9150.0
OR4M1 -9138.0
OR6V1 -9092.0
OR10A7 -9064.0
OR56B1 -9052.0
OR13C3 -9050.0
OR10V1 -8990.0
OR51A7 -8978.0
OR51I1 -8943.0
OR5K1 -8930.0
OR10A4 -8928.0
OR4E2 -8907.0
OR4K5 -8898.0
OR6N1 -8792.0
OR2AP1 -8732.0
OR4C12 -8700.0
OR2L2 -8684.0
CNGB1 -8680.0
OR4C45 -8665.0
OR6P1 -8660.0
OR5H15 -8585.0
OR6N2 -8583.0
OR2D3 -8553.0
OR13F1 -8537.0
OR51B4 -8490.0
OR5K2 -8484.0
OR52R1 -8465.0
OR8H1 -8448.5
OR6T1 -8397.0
OR1G1 -8383.0
OR5K3 -8361.0
OR10A5 -8328.0
OR4C6 -8280.0
OR6K6 -8127.0
OR10G9 -8121.0
OR6C65 -8071.0
OR5M1 -8048.0
OR2T12 -7996.0
OR2T1 -7869.0
OR2B11 -7736.0
OR5M9 -7722.0
OR5T2 -7719.0
OR5K4 -7678.0
OR5L2 -7623.0
OR8J3 -7619.0
OR7G2 -7520.0
OR2M3 -7482.0
OR7A5 -7368.0
OR51M1 -7307.0
OR5T3 -7252.0
OR52I2 -7150.0
ANO2 -7144.0
OR8U1 -7140.0
OR10T2 -7116.0
OR1B1 -7095.0
OR8S1 -6967.0
OR13A1 -6945.0
RTP1 -6908.0
OR2S2 -6866.0
OR2L8 -6828.0
OR2Z1 -6826.0
OR4C3 -6722.0
OR5B12 -6624.0
OR8K5 -6599.0
OR2AG1 -6579.0
OR10A6 -6542.0
OR8D2 -6264.0
OR1L6 -6188.0
OR51B2 -6172.0
OR5J2 -6131.0
OR5W2 -6083.0
OR51E2 -6074.0
OR5A1 -6016.0
OR14A16 -6009.0
OR10J1 -6007.0
OR4K1 -5993.0
OR5D18 -5969.0
OR2AT4 -5942.0
OR52D1 -5733.0
OR4D1 -5728.0
OR2L13 -5656.0
OR7D2 -5625.0
OR5P2 -5607.0
OR52K1 -5551.0
OR14I1 -5474.0
OR2H2 -5435.0
OR6C74 -5418.0
OR51B6 -5356.0
OR1M1 -5342.0
OR51L1 -5269.0
OR4X2 -5264.0
OR1A2 -4943.0
OR1D2 -4940.0
OR5M10 -4923.0
OR2K2 -4905.0
OR1L4 -4686.0
OR6K3 -4201.0
OR6C76 -4178.0
OR5I1 -4142.0
OR4A15 -4079.0
OR5L1 -3940.5
OR7C2 -3841.0
OR9A2 -3741.0
OR2J2 -3615.0
OR11H6 -3608.0
OR2L5 -3566.0
OR2A12 -3535.0
OR10H1 -3533.0
OR1S2 -3495.0
OR10H5 -3405.0
OR4D10 -3387.0
OR4K17 -3386.0
OR5AS1 -3372.0
OR8D1 -3295.0
OR51G1 -3279.0
OR7G3 -3267.0
OR51F1 -3260.0
ADCY3 -3259.0
OR10H3 -3160.0
OR51V1 -2555.0
OR2AE1 -2547.0
OR6C4 -2539.0
OR1L3 -2440.0
OR52L1 -2312.0
OR52E4 -2143.0
OR9Q2 -2015.0
OR51Q1 -1896.0
REEP1 -1863.0
OR10A2 -1820.0
OR2T4 -1718.0
OR5V1 -1387.0
OR6A2 -1277.0
OR10H2 -1250.0
OR1I1 -1228.0
OR51G2 -1133.0
OR6C3 -1114.0
OR4A5 -1018.0
OR2W1 -996.0
OR1K1 -984.0
OR4L1 -881.0
OR1C1 -857.0
OR51B5 -823.0
OR8H3 -788.0
OR4S1 -668.0
OR6B3 -510.0
OR52M1 -501.0
OR4K14 -45.0
OR5P3 247.0
OR8K1 295.0
OR2G6 347.0
OR3A3 393.0
OR2H1 479.0
EBF1 585.0
OR1N2 635.0
OR2B2 682.0
OR6C70 745.0
OR8G1 868.0
OR13C8 909.0
OR13C9 1153.0
GNAL 1183.0
OR8U8 1199.0
OR1S1 1262.0
OR13C2 1554.0
OR6F1 1664.0
OR9K2 1681.0
OR5B17 1868.0
GNB1 1983.0
OR6C2 2139.0
OR14J1 2413.0
OR6S1 2664.0
OR52A1 2691.0
OR51T1 2797.0
OR6M1 3089.0
OR1F1 3100.0
OR10H4 3128.0
OR52N1 3218.0
OR10G3 3268.0
OR56A5 3369.0
OR52E8 3609.0
OR7G1 3785.0
OR1A1 3833.0
OR11G2 3853.0
OR7E24 3904.0
OR8D4 4145.0
OR5B3 4717.0
OR2B3 5032.0
GNG13 5069.0
OR9G1 5083.5
OR9G9 5083.5
OR8U3 5158.0
OR4X1 5281.0
OR52A5 5322.0
OR2G2 5374.0
OR56B4 5452.0
OR51F2 5561.0
OR6B2 5588.0
OR4B1 5711.0
OR52N2 5830.0
OR1E1 5862.0
OR56A4 5865.0
OR4N2 6116.0
OR2AK2 6268.0
OR4C15 6288.0
OR9A4 6299.0
OR5AR1 6516.0
OR2C1 6581.0
OR52B2 6880.0
OR5H6 6895.0
OR52I1 6917.0
OR4A16 6970.0
OR2T8 6975.0
OR1L1 7032.0
OR5AP2 7038.0
OR5H2 7063.0
OR2T6 7077.0
OR12D2 7150.0
OR2M5 7167.0
OR2A5 7335.0
OR2D2 7488.0
OR9I1 7824.0
LDB1 7864.0
OR2T27 7875.0
OR11H4 7966.0
OR2M2 7970.0
OR9Q1 8227.0
OR4A47 8310.0
OR2L3 8342.0
OR4K2 8378.0
OR4K15 8427.0
OR10J5 8485.0
OR5D16 8649.0
OR4D2 8653.0
OR2A14 8678.0
OR14C36 8718.0
OR5D14 8759.0
OR12D3 8860.0
LHX2 8901.0
OR52K2 9001.0
OR4F6 9038.0
OR13J1 9069.0
OR8B12 9087.0
OR2T33 9153.0
OR5T1 9213.0
OR9G4 9244.0
OR8G5 9276.0
OR51A2 9441.0
OR1J4 9545.0
OR13C4 9590.0
OR5AU1 9634.0
OR4D9 9828.0
OR4N5 9881.0
OR1E2 9936.0
OR10AG1 10088.0
OR5M3 10124.0
OR10P1 10144.0
OR5D13 10180.0
OR2T11 10202.0
OR6B1 10217.0
OR4C46 10238.0
OR10W1 10302.0
OR2M7 10445.0
OR3A2 10596.0
OR52E2 10725.0
OR4K13 10886.0
OR5A2 10941.0
OR2T3 10976.0
OR6Q1 11015.0
OR6C6 11128.0


REACTOME_NEUTROPHIL_DEGRANULATION

REACTOME_NEUTROPHIL_DEGRANULATION
1053
set REACTOME_NEUTROPHIL_DEGRANULATION
setSize 460
pANOVA 7.27e-13
s.dist 0.195
p.adjustANOVA 3.98e-10



Top enriched genes

Top 20 genes
GeneID Gene Rank
S100A8 11160
TYROBP 11155
MPO 11143
AZU1 11131
FCER1G 11099
FGR 11089
RNASE3 11070
CEACAM6 11063
DEFA4 11054
RNASE2 11039
PRTN3 11038
CTSG 11021
VAT1 11017
LRG1 11006
FOLR3 10996
LILRB2 10980
CD68 10957
S100P 10898
ELANE 10883
RAB3D 10843

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
S100A8 11160
TYROBP 11155
MPO 11143
AZU1 11131
FCER1G 11099
FGR 11089
RNASE3 11070
CEACAM6 11063
DEFA4 11054
RNASE2 11039
PRTN3 11038
CTSG 11021
VAT1 11017
LRG1 11006
FOLR3 10996
LILRB2 10980
CD68 10957
S100P 10898
ELANE 10883
RAB3D 10843
MS4A3 10829
BIN2 10824
DOK3 10819
S100A9 10770
PGLYRP1 10757
CHI3L1 10752
ADGRG3 10721
STING1 10715
CTSD 10690
RHOG 10688
CLEC12A 10634
GSN 10627
NRAS 10599
ADGRE3 10592
TARM1 10505
CD33 10455
P2RX1 10433
OSCAR 10403
CFD 10401
SLC11A1 10399
PYCARD 10296
NDUFC2 10283
OLFM4 10255
GSTP1 10237
ATP6V0A1 10214
LCN2 10211
RETN 10189
CXCR2 10169
CTSZ 10153
NME2 10006
TBC1D10C 9962
PTPRJ 9930
B4GALT1 9910
CD14 9901
FTL 9804
OSTF1 9801
RAB37 9774
LAIR1 9772
SLPI 9736
GMFG 9722
PLAUR 9604
CEACAM3 9580
LYZ 9574
HSPA6 9572
CDA 9563
PRKCD 9555
ORMDL3 9553
CD59 9485
CPNE3 9453
RAB7A 9450
PGM2 9438
CTSC 9256
GCA 9239
CXCR1 9171
FPR2 9149
GHDC 9132
ARPC5 9080
HEBP2 9048
SNAP23 9013
ATP6V1D 8997
PSMD13 8956
S100A11 8935
MAPK14 8871
DBNL 8749
ADGRE5 8734
C1orf35 8699
MMP9 8639
GPR84 8630
CD63 8583
ATP6V0C 8558
SIGLEC9 8524
FABP5 8497
PRG2 8452
OLR1 8419
ALAD 8417
MNDA 8369
STOM 8349
C5AR1 8330
CYB5R3 8320
APRT 8245
PNP 8243
VAPA 8228
CAMP 8195
PSMB7 8153
RAP1A 8080
GRN 8000
ACP3 7946
PLAU 7883
CYSTM1 7877
SLC15A4 7844
BST2 7771
BRI3 7760
HSPA1A 7743
TMEM179B 7740
SDCBP 7725
SIRPB1 7698
CCT8 7641
GNS 7615
GM2A 7579
CR1 7561
LAMTOR1 7542
TSPAN14 7507
MGST1 7485
VAMP8 7442
SIRPA 7412
TRPM2 7407
MANBA 7329
SERPINB1 7261
XRCC5 7219
DSG1 7175
CD177 7126
GLIPR1 7120
TNFAIP6 6936
RAB31 6884
RAB10 6810
AMPD3 6762
YPEL5 6758
SERPINB10 6754
B2M 6729
EPX 6607
RAB5C 6560
UNC13D 6530
SERPINA1 6522
CAB39 6468
VCL 6397
NCKAP1L 6393
HP 6371
MLEC 6335
NIT2 6324
PRG3 6202
HSP90AB1 6186
SERPINB6 6167
COMMD3 6121
DSN1 6095
HMGB1 5972
TUBB4B 5904
CREG1 5880
LAMTOR3 5852
LTF 5848
GGH 5842
CDK13 5829
PSMD12 5712
CXCL1 5682
CAT 5678
SYNGR1 5639
IDH1 5637
PSMD3 5632
PADI2 5616
COTL1 5609
ARSA 5536
TLR2 5534
PSMB1 5505
RAB5B 5491
DNAJC3 5445
HLA-B 5425
GOLGA7 5408
FCAR 5346
TICAM2 5257
PLEKHO2 5139
PSMA2 5121
LILRA3 5071
CD47 5035
PSAP 5025
PSMC3 4952
RAB27A 4919
IQGAP2 4861
ILF2 4830
LGALS3 4818
DEGS1 4780
PLD1 4738
STK11IP 4673
CAP1 4635
ATG7 4561
HVCN1 4494
AGL 4425
BST1 4406
PA2G4 4391
CLEC5A 4369
CD55 4245
PSEN1 4160
HEXB 4094
QPCT 4073
TMEM30A 4024
DYNLL1 4014
STK10 3945
KPNB1 3909
ARSB 3737
ARMC8 3723
PSMD14 3675
TXNDC5 3666
SURF4 3649
FTH1 3639
ADAM10 3627
RAP1B 3595
GDI2 3572
TIMP2 3529
ITGAM 3504
ENPP4 3431
NHLRC3 3403
ATP8B4 3253
DNAJC13 3219
HPSE 3195
CEP290 3155
CD58 3149
CSNK2B 3095
FCN1 3093
HSPA8 3085
DIAPH1 3026
CTSA 3017
PGAM1 2992
AGPAT2 2945
PRDX6 2907
PIGR 2892
SVIP 2827
STBD1 2792
PGM1 2787
DOCK2 2764
KCMF1 2683
SCAMP1 2626
PAFAH1B2 2623
ARHGAP45 2579
DNAJC5 2571
FAF2 2550
ASAH1 2534
FLG2 2481
MCEMP1 2381
SLC2A5 2344
TCN1 2343
FUCA1 2319
NAPRT 2312
CMTM6 2301
MIF 2231
DYNC1LI1 2058
CAPN1 2045
CSTB 2029
CTSB 2023
NBEAL2 1992
CD44 1970
MAN2B1 1822
PKM 1780
CD93 1767
LAMTOR2 1697
TUBB 1674
RHOF 1638
FGL2 1618
ANO6 1521
ITGAL 1490
S100A12 1431
DERA 1396
LTA4H 1382
ITGAV 1347
ALDOA 1247
ITGAX 1235
PLAC8 1163
ADAM8 1152
CTSS 1093
PTAFR 993
ACTR2 930
ROCK1 906
CLEC4C 885
ALDOC 788
PSMD7 646
PSMD6 620
DGAT1 507
PDXK 496
PTPRC 485
CD53 476
RAB6A 389
COPB1 337
RHOA 285
GLB1 197
TOM1 138
SIGLEC14 -59
ORM2 -78
XRCC6 -251
PRCP -266
ARG1 -293
PPBP -306
GPI -315
CNN2 -330
MAPK1 -343
PSMD11 -439
ORM1 -511
PSMD2 -547
CEACAM8 -649
ANXA2 -686
SRP14 -731
IST1 -778
MMP25 -780
QSOX1 -795
RAB3A -844
TOLLIP -904
GSDMD -963
ACTR10 -971
PYGL -1019
TMBIM1 -1117
CEACAM1 -1243
ARL8A -1371
TMEM63A -1377
ADA2 -1383
IMPDH2 -1397
PTPRB -1432
CAND1 -1446
SLC44A2 -1447
GYG1 -1506
KCNAB2 -1515
ACTR1B -1640
RAB14 -1731
PSMA5 -1800
AP1M1 -2047
CTSH -2052
CCT2 -2115
IRAG2 -2162
PPIA -2269
AP2A2 -2368
LPCAT1 -2389
RAC1 -2468
APAF1 -2526
FRK -2529
PDAP1 -2750
CRISPLD2 -2754
TCIRG1 -2874
IGF2R -2886
C3AR1 -3048
TMC6 -3053
VNN1 -3067
HRNR -3091
LRRC7 -3222
HLA-C -3246
ATP11B -3354
HGSNAT -3368
NPC2 -3377
HSPA1B -3482
HLA-A -3534
ARHGAP9 -3547
ITGB2 -3578
DDOST -3614
FUCA2 -3686
MVP -3727
RAB18 -3768
SELL -3771
NFAM1 -3830
ABCA13 -3850
HMOX2 -3881
CPNE1 -3883
AGA -3887
NFKB1 -3915
IMPDH1 -3916
PTGES2 -3964
TRAPPC1 -4076
CD300A -4090
SNAP29 -4177
SLC27A2 -4180
SLC2A3 -4223
APEH -4230
PSMC2 -4425
GALNS -4507
HK3 -4540
DYNLT1 -4582
UBR4 -4703
DPP7 -4794
PTX3 -4817
HSP90AA1 -4827
ACAA1 -4846
CPPED1 -5009
DSP -5072
NCSTN -5119
DYNC1H1 -5136
SLCO4C1 -5181
ATP8A1 -5380
CLEC4D -5414
IQGAP1 -5421
BPI -5428
PSMD1 -5434
CHIT1 -5640
TTR -5794
MME -5895
ALDH3B1 -5967
ALOX5 -6026
EEF1A1 -6174
RNASET2 -6200
ERP44 -6341
C6orf120 -6398
MGAM -6409
HBB -6457
PKP1 -6481
PYGB -6503
A1BG -6552
CHRNB4 -6613
COMMD9 -6614
PTPN6 -6621
VPS35L -6626
VCP -6635
RAB44 -6694
NEU1 -6695
SNAP25 -6716
ACLY -6731
CYBA -6835
FCGR2A -7016
SERPINA3 -7055
RAP2B -7186
CRACR2A -7201
ANPEP -7258
AHSG -7280
FCGR3B -7363
TNFRSF1B -7491
PTPRN2 -7542
NFASC -7592
SERPINB12 -7593
SERPINB3 -7601
CANT1 -7685
LILRB3 -7758
SPTAN1 -7825
DSC1 -7921
JUP -7950
ATAD3B -7993
PFKL -8039
RAB4B -8078
CKAP4 -8206
CD36 -8219
PRSS3 -8389
EEF2 -8509
PPIE -8536
SIGLEC5 -8565
C3 -8607
GAA -8666
KRT1 -8695
LAMP1 -8793
ATP11A -8849
GUSB -8969
S100A7 -9091
RAB24 -9388
CST3 -9464
CYFIP1 -9552
CRISP3 -9767
CALML5 -10081
FPR1 -10227
MMP8 -10228
PECAM1 -10282
AOC1 -10423


REACTOME_INNATE_IMMUNE_SYSTEM

REACTOME_INNATE_IMMUNE_SYSTEM
227
set REACTOME_INNATE_IMMUNE_SYSTEM
setSize 1002
pANOVA 3.05e-09
s.dist 0.111
p.adjustANOVA 1.25e-06



Top enriched genes

Top 20 genes
GeneID Gene Rank
S100A8 11160
TYROBP 11155
MPO 11143
AZU1 11131
FCER1G 11099
FGR 11089
RNASE3 11070
CEACAM6 11063
DEFA4 11054
RNASE2 11039
PRTN3 11038
CTSG 11021
VAT1 11017
C5AR2 11010
LRG1 11006
FOLR3 10996
LILRB2 10980
CD68 10957
CD300LB 10951
S100P 10898

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
S100A8 11160.0
TYROBP 11155.0
MPO 11143.0
AZU1 11131.0
FCER1G 11099.0
FGR 11089.0
RNASE3 11070.0
CEACAM6 11063.0
DEFA4 11054.0
RNASE2 11039.0
PRTN3 11038.0
CTSG 11021.0
VAT1 11017.0
C5AR2 11010.0
LRG1 11006.0
FOLR3 10996.0
LILRB2 10980.0
CD68 10957.0
CD300LB 10951.0
S100P 10898.0
ELANE 10883.0
RAB3D 10843.0
MS4A3 10829.0
BIN2 10824.0
DOK3 10819.0
S100A9 10770.0
PGLYRP1 10757.0
CCL22 10754.0
CHI3L1 10752.0
ADGRG3 10721.0
STING1 10715.0
CTSD 10690.0
RHOG 10688.0
IFNA16 10685.0
DEFB1 10678.0
CLEC12A 10634.0
GSN 10627.0
DEFB133 10625.0
PGLYRP2 10602.0
NRAS 10599.0
ADGRE3 10592.0
IL1B 10591.0
DEFA6 10584.0
CLEC10A 10561.0
RAC2 10554.0
DUSP3 10526.0
TARM1 10505.0
CD33 10455.0
SIGLEC15 10442.0
P2RX1 10433.0
RNASE7 10422.0
TLR9 10408.0
OSCAR 10403.0
CFD 10401.0
SLC11A1 10399.0
IFNA1 10388.0
UBA7 10383.0
PYCARD 10296.0
CFHR5 10295.0
NDUFC2 10283.0
OLFM4 10255.0
UNC93B1 10252.0
GSTP1 10237.0
ATP6V0A1 10214.0
LCN2 10211.0
P2RX7 10191.0
RETN 10189.0
CXCR2 10169.0
CTSZ 10153.0
CLU 10138.0
GRB2 10092.0
NKIRAS2 10063.0
PSMA1 10043.0
ITLN1 10010.0
REG3A 10009.0
NME2 10006.0
CD300E 9996.0
DEFB124 9967.0
NOD1 9966.0
TBC1D10C 9962.0
PIK3R2 9942.0
PTPRJ 9930.0
B4GALT1 9910.0
CTSV 9903.0
CD14 9901.0
CD209 9880.0
RNF135 9824.0
FTL 9804.0
OSTF1 9801.0
SAA1 9781.0
CFI 9778.0
NCF2 9776.0
RAB37 9774.0
LAIR1 9772.0
UBE2N 9761.0
LPO 9748.0
FCN2 9747.0
SLPI 9736.0
CTSK 9728.0
GMFG 9722.0
TLR6 9697.0
CD180 9662.0
RPS6KA1 9650.0
NLRP3 9638.0
PLAUR 9604.0
PSMA6 9587.0
CEACAM3 9580.0
LYZ 9574.0
HSPA6 9572.0
CDA 9563.0
FCGR3A 9561.0
PSMB10 9558.0
PRKCD 9555.0
ORMDL3 9553.0
TLR3 9536.0
HSP90B1 9489.0
CD59 9485.0
CPNE3 9453.0
IRAK3 9452.0
RAB7A 9450.0
SHC1 9449.0
TREX1 9442.0
PGM2 9438.0
ICAM3 9384.0
NCKIPSD 9380.0
PELI3 9344.0
UBC 9309.0
ATP6V0E2 9278.0
CTSC 9256.0
DEFB110 9243.0
GCA 9239.0
CXCR1 9171.0
FPR2 9149.0
GHDC 9132.0
IFNA7 9083.0
ARPC5 9080.0
HEBP2 9048.0
SNAP23 9013.0
CCR2 9002.0
ATP6V1D 8997.0
PSMD13 8956.0
MAP2K1 8942.0
S100A11 8935.0
MAPK14 8871.0
HTN1 8848.0
MUC12 8845.0
DBNL 8749.0
ADGRE5 8734.0
SARM1 8730.0
C1orf35 8699.0
NLRC4 8689.0
PGLYRP4 8679.0
MMP9 8639.0
GPR84 8630.0
TRIM21 8622.0
TLR5 8613.0
ABI1 8595.0
CD63 8583.0
ATP6V0C 8558.0
DEFB116 8532.0
SIGLEC9 8524.0
FABP5 8497.0
PRG2 8452.0
OLR1 8419.0
ALAD 8417.0
MNDA 8369.0
MAP3K8 8362.0
STOM 8349.0
C5AR1 8330.0
CYB5R3 8320.0
APRT 8245.0
PNP 8243.0
UBE2V1 8231.0
VAPA 8228.0
LCK 8208.0
CAMP 8195.0
SIGIRR 8194.0
CHGA 8189.0
ATG12 8173.0
FGA 8162.0
UBE2L6 8158.0
PSMB7 8153.0
NCR2 8134.0
RAP1A 8080.0
POLR2K 8079.0
TXN 8058.0
RIPK3 8050.0
CASP10 8044.0
GRN 8000.0
ELMO1 7988.0
GAB2 7974.0
TREM1 7960.0
ACP3 7946.0
PLAU 7883.0
CYSTM1 7877.0
SLC15A4 7844.0
TRIM4 7806.0
BST2 7771.0
BRI3 7760.0
MYD88 7749.0
HSPA1A 7743.0
TMEM179B 7740.0
DNM2 7734.0
ATP6V1G1 7733.0
SDCBP 7725.0
SIRPB1 7698.0
MAP3K14 7646.0
CCT8 7641.0
GNS 7615.0
ITPR2 7603.0
GM2A 7579.0
CLEC4E 7566.0
CR1 7561.0
DEFB118 7560.0
LAMTOR1 7542.0
ATP6V1E1 7537.0
IFIH1 7510.0
TSPAN14 7507.0
FOS 7498.0
MGST1 7485.0
TLR4 7476.0
VAMP8 7442.0
SIRPA 7412.0
TRPM2 7407.0
S100B 7344.0
MANBA 7329.0
C8A 7302.0
NKIRAS1 7269.0
PPP3R1 7266.0
SERPINB1 7261.0
XRCC5 7219.0
ARPC1B 7217.0
ITPR1 7193.0
DSG1 7175.0
TLR1 7139.0
CD177 7126.0
GLIPR1 7120.0
RNF125 7111.0
TRAF6 7001.0
WIPF1 6966.0
TNFAIP6 6936.0
STAT6 6912.0
RAB31 6884.0
MAP3K7 6877.0
ATP6V1B2 6875.0
RAB10 6810.0
HCK 6804.0
FBXW11 6800.0
UBB 6789.0
AMPD3 6762.0
YPEL5 6758.0
SERPINB10 6754.0
PELI2 6745.0
B2M 6729.0
GRAP2 6657.0
TOMM70 6654.0
AHCYL1 6630.0
LGMN 6623.0
MAP3K1 6622.0
ELMO2 6618.0
EPX 6607.0
KRAS 6597.0
CDC42 6585.0
RAB5C 6560.0
CLEC4A 6536.0
UNC13D 6530.0
PCBP2 6525.0
SERPINA1 6522.0
CASP1 6508.0
CAB39 6468.0
DEFB126 6443.0
TEC 6441.0
VCL 6397.0
NCKAP1L 6393.0
HP 6371.0
PSMB4 6341.0
MLEC 6335.0
ICAM2 6330.0
NIT2 6324.0
TBK1 6319.0
CASP8 6261.0
PRKACA 6257.0
S100A7A 6233.0
PRG3 6202.0
HSP90AB1 6186.0
SERPINB6 6167.0
LYN 6131.0
COMMD3 6121.0
CUL1 6104.0
MEFV 6096.0
DSN1 6095.0
SOCS1 6069.0
HMGB1 5972.0
TUBB4B 5904.0
C4BPA 5889.0
CREG1 5880.0
LAMTOR3 5852.0
LTF 5848.0
GGH 5842.0
CDK13 5829.0
PSMD12 5712.0
CXCL1 5682.0
CAT 5678.0
ABI2 5676.0
SYNGR1 5639.0
IDH1 5637.0
PSMD3 5632.0
PADI2 5616.0
COTL1 5609.0
VAV3 5601.0
ARSA 5536.0
TLR2 5534.0
PSME3 5531.0
PSMB1 5505.0
RAB5B 5491.0
C1QC 5466.0
DNAJC3 5445.0
HLA-B 5425.0
GOLGA7 5408.0
ATP6V0D2 5348.0
FCAR 5346.0
PSMA3 5324.0
C8G 5309.0
SRC 5308.0
DNM3 5286.0
TICAM2 5257.0
PSMC1 5255.0
VAV1 5248.0
POLR3G 5247.0
LRRFIP1 5242.0
BCL10 5201.0
BIRC3 5187.0
POLR3D 5149.0
PLEKHO2 5139.0
PSMA2 5121.0
LILRA3 5071.0
CD47 5035.0
PSAP 5025.0
ATP6V1C1 4973.0
PSMC3 4952.0
ATP6V1A 4948.0
RAB27A 4919.0
FADD 4876.0
IQGAP2 4861.0
ILF2 4830.0
LGALS3 4818.0
NOD2 4792.0
DEGS1 4780.0
CALM1 4775.0
RASGRP2 4764.0
PLD1 4738.0
PRKACB 4691.0
MUC5AC 4687.0
STK11IP 4673.0
CAP1 4635.0
MUC1 4610.0
PELI1 4599.0
ATG7 4561.0
IFI16 4557.0
DEFB121 4540.0
USP14 4516.0
SERPING1 4513.0
HVCN1 4494.0
PSMC4 4459.0
MAPK13 4435.0
LY86 4426.0
AGL 4425.0
BST1 4406.0
PA2G4 4391.0
BCL2 4375.0
CLEC5A 4369.0
PIK3C3 4286.0
CD55 4245.0
NLRP1 4221.0
PSEN1 4160.0
WASF2 4121.0
HEXB 4094.0
QPCT 4073.0
TMEM30A 4024.0
DYNLL1 4014.0
PSMA7 3991.0
MAP2K6 3981.0
STK10 3945.0
KPNB1 3909.0
MUC15 3889.0
PIK3R1 3783.0
RNASE6 3743.0
CLEC7A 3740.0
ARSB 3737.0
SOS1 3727.0
ARMC8 3723.0
POLR3H 3715.0
PSMD14 3675.0
TXNDC5 3666.0
SURF4 3649.0
LIMK1 3645.0
FTH1 3639.0
MUC7 3634.0
ADAM10 3627.0
RAF1 3597.0
RAP1B 3595.0
DEFB104A 3584.5
DEFB104B 3584.5
GDI2 3572.0
TIMP2 3529.0
CPN1 3516.0
ITGAM 3504.0
ARPC3 3484.0
UBE2D3 3479.0
ENPP4 3431.0
NHLRC3 3403.0
IRF7 3360.0
DHX9 3346.0
PSTPIP1 3286.0
WASF1 3279.0
MYO5A 3278.0
LRRC14 3274.0
ATP8B4 3253.0
DNAJC13 3219.0
HPSE 3195.0
CAPZA1 3188.0
KLRD1 3186.0
DEFB127 3172.0
POLR2H 3166.0
CEP290 3155.0
CD58 3149.0
CSNK2B 3095.0
FCN1 3093.0
HSPA8 3085.0
DIAPH1 3026.0
PPP2R1B 3019.0
CTSA 3017.0
PGAM1 2992.0
ACTR3 2950.0
AGPAT2 2945.0
IRAK2 2933.0
POLR2L 2911.0
PRDX6 2907.0
BPIFA1 2904.0
PIGR 2892.0
TKFC 2844.0
PTK2 2838.0
SVIP 2827.0
CRK 2818.0
UBA3 2796.0
STBD1 2792.0
PGM1 2787.0
DOCK2 2764.0
KCMF1 2683.0
TICAM1 2667.0
PSMC5 2665.0
NOS3 2662.0
SCAMP1 2626.0
PAFAH1B2 2623.0
ARHGAP45 2579.0
DNAJC5 2571.0
FAF2 2550.0
ASAH1 2534.0
SYK 2502.0
MYO9B 2484.0
FLG2 2481.0
POLR2F 2465.0
TAX1BP1 2456.0
PLD2 2426.0
MAPK10 2410.0
PLD3 2390.0
MCEMP1 2381.0
PLD4 2347.0
SLC2A5 2344.0
TCN1 2343.0
FUCA1 2319.0
NAPRT 2312.0
CMTM6 2301.0
POLR1D 2279.0
AAMP 2269.0
ATP6V1F 2265.0
MIF 2231.0
IFNA6 2215.0
FGG 2131.0
DYNC1LI1 2058.0
CAPN1 2045.0
CSTB 2029.0
CTSB 2023.0
UBA52 2012.0
NBEAL2 1992.0
DHX58 1971.0
CD44 1970.0
CPB2 1888.0
MAN2B1 1822.0
ATOX1 1811.0
NFKB2 1809.0
EEA1 1791.0
PKM 1780.0
CD93 1767.0
PSME4 1702.0
LAMTOR2 1697.0
PAK1 1687.0
TUBB 1674.0
APP 1659.0
RHOF 1638.0
FGL2 1618.0
PSME2 1571.0
ATP6V1G3 1556.0
S100A1 1532.0
ANO6 1521.0
NCKAP1 1503.0
ITGAL 1490.0
MAP2K4 1464.0
S100A12 1431.0
HERC5 1430.0
NLRC5 1429.0
DERA 1396.0
LTA4H 1382.0
ITGAV 1347.0
HMOX1 1310.0
DUSP6 1294.0
MAPK8 1248.0
ALDOA 1247.0
C8B 1246.0
ITGAX 1235.0
POLR3GL 1184.0
PPP2R1A 1180.0
PLAC8 1163.0
ADAM8 1152.0
LEAP2 1125.0
MEF2C 1109.0
CTSS 1093.0
DEFB125 1068.0
POLR1C 1063.0
PTAFR 993.0
ITCH 944.0
ACTR2 930.0
ROCK1 906.0
CTSL 886.0
CLEC4C 885.0
DCD 840.0
DEFA5 818.0
LAT2 793.0
ALDOC 788.0
GZMM 771.0
PI3 735.0
UBE2M 724.0
PLPP5 662.0
PSMD7 646.0
ABL1 644.0
PSMD6 620.0
NCF4 569.0
PSMB3 544.0
MRE11 513.0
TREM2 510.0
DGAT1 507.0
PDXK 496.0
PTPRC 485.0
CD53 476.0
LCP2 466.0
TRAF3 449.0
CREB1 418.0
ATP6V0E1 406.0
RAB6A 389.0
TRIM32 340.0
COPB1 337.0
SEM1 292.0
RHOA 285.0
GLB1 197.0
POLR3C 188.0
BIRC2 154.0
TOM1 138.0
IRAK4 129.0
NF2 110.0
PIK3CB 107.0
SKP1 51.0
SIGLEC14 -59.0
CNPY3 -60.0
ORM2 -78.0
XRCC6 -251.0
PIN1 -261.0
PRCP -266.0
TNFAIP3 -278.0
ZBP1 -291.0
ARG1 -293.0
PSMC6 -296.0
MAPKAPK3 -304.0
PPBP -306.0
NCK1 -309.0
GPI -315.0
CNN2 -330.0
MAPK1 -343.0
PSMA4 -401.0
PSMD11 -439.0
ECSIT -444.0
ORM1 -511.0
POLR3F -526.0
POLR3K -530.0
PSMD2 -547.0
NFKBIB -565.0
PSMB2 -611.0
PSMA8 -621.0
CEACAM8 -649.0
PANX1 -654.0
ANXA2 -686.0
ARPC4 -689.0
CFH -705.0
SRP14 -731.0
BPIFB1 -733.0
DHX36 -758.0
IST1 -778.0
MMP25 -780.0
QSOX1 -795.0
MYO1C -819.0
PSMD5 -828.0
FCER1A -831.0
NFATC3 -832.0
RAB3A -844.0
PSMF1 -878.0
TOLLIP -904.0
ATP6V0B -915.0
BCL2L1 -922.0
GSDMD -963.0
ACTR10 -971.0
PYGL -1019.0
PIK3R4 -1035.0
TMBIM1 -1117.0
PIK3CA -1136.0
C4A -1161.5
C4B -1161.5
ITK -1193.0
MAP2K3 -1194.0
PSMB8 -1223.0
CEACAM1 -1243.0
RIGI -1264.0
CFL1 -1276.0
TANK -1302.0
RASGRP1 -1313.0
ARL8A -1371.0
TMEM63A -1377.0
ADA2 -1383.0
IFNA13 -1395.0
IMPDH2 -1397.0
PTPRB -1432.0
ATP6V0A2 -1434.0
CAND1 -1446.0
SLC44A2 -1447.0
GYG1 -1506.0
KCNAB2 -1515.0
ATF1 -1525.0
ACTB -1544.0
DNM1 -1554.0
RELA -1562.0
C6 -1575.0
PSMD4 -1623.0
ACTR1B -1640.0
RAB14 -1731.0
PRKCE -1750.0
PPP3CA -1755.0
PSMA5 -1800.0
CHUK -1813.0
SFTPD -1871.0
CTNNB1 -1892.0
ISG15 -1906.0
POLR2E -1933.0
UBE2K -1982.0
MAPK7 -2007.0
ATP6V1H -2038.0
AP1M1 -2047.0
CTSH -2052.0
CCT2 -2115.0
DEFB119 -2123.0
NOS1 -2131.0
APOB -2139.0
RIPK2 -2148.0
IRAG2 -2162.0
ATP6V1E2 -2176.0
VRK3 -2210.0
PSMD9 -2254.0
PPIA -2269.0
PRKCQ -2320.0
AP2A2 -2368.0
LPCAT1 -2389.0
GSDME -2390.0
MYH9 -2391.0
MUC13 -2398.0
BTRC -2464.0
MALT1 -2465.0
RAC1 -2468.0
CREBBP -2481.0
PSMB5 -2516.0
APAF1 -2526.0
FRK -2529.0
MAPK12 -2569.0
GNLY -2605.0
MUC21 -2666.0
TIFA -2673.0
TLR10 -2716.0
DEFB123 -2728.0
PDAP1 -2750.0
CRISPLD2 -2754.0
MAPKAPK2 -2865.0
TCIRG1 -2874.0
IGF2R -2886.0
ARPC2 -2904.0
DEFB113 -2906.0
ATP6V1G2 -2939.0
CR2 -2972.0
IKBIP -2982.0
CFHR4 -3003.0
C3AR1 -3048.0
TMC6 -3053.0
FCN3 -3063.0
VNN1 -3067.0
ATF2 -3071.0
HRNR -3091.0
DUSP4 -3134.0
LY96 -3154.0
DEFB128 -3197.0
TP53 -3217.0
LRRC7 -3222.0
PTPN11 -3223.0
C1R -3239.0
HLA-C -3246.0
CCL17 -3274.0
ATP11B -3354.0
HGSNAT -3368.0
CD247 -3369.0
NPC2 -3377.0
WIPF2 -3378.0
MAPK11 -3380.0
AIM2 -3393.0
AGER -3463.0
HSPA1B -3482.0
RNASE8 -3525.0
UBE2D2 -3526.0
PRKCSH -3532.0
HLA-A -3534.0
ARHGAP9 -3547.0
REG3G -3553.0
ITGB2 -3578.0
DDOST -3614.0
PPP2CB -3621.0
PPP2CA -3664.0
CD46 -3680.0
FUCA2 -3686.0
CYLD -3705.0
MVP -3727.0
TXK -3738.0
ATP6V0D1 -3765.0
RAB18 -3768.0
SELL -3771.0
WASF3 -3795.0
ART1 -3802.0
N4BP1 -3816.0
NFAM1 -3830.0
WIPF3 -3842.0
ABCA13 -3850.0
PSMB9 -3852.0
UBE2D1 -3873.0
HMOX2 -3881.0
CPNE1 -3883.0
AGA -3887.0
NFKB1 -3915.0
IMPDH1 -3916.0
PTGES2 -3964.0
YES1 -4047.0
TRAPPC1 -4076.0
CD300A -4090.0
BRK1 -4095.0
KLRK1 -4098.0
DEFB115 -4109.0
WASL -4119.0
CASP9 -4145.0
SNAP29 -4177.0
SLC27A2 -4180.0
DUSP7 -4215.0
SLC2A3 -4223.0
APEH -4230.0
MAVS -4237.0
C7 -4248.0
RNF216 -4301.0
NLRX1 -4336.0
TRIM25 -4381.0
DTX4 -4387.0
PSMC2 -4425.0
ATP6V1B1 -4499.0
GALNS -4507.0
RBSN -4538.0
HK3 -4540.0
PROS1 -4555.0
DYNLT1 -4582.0
TNIP2 -4587.0
UBR4 -4703.0
C2 -4784.0
DPP7 -4794.0
FYN -4809.0
PTX3 -4817.0
HSP90AA1 -4827.0
ACAA1 -4846.0
POLR3B -4863.0
ACTG1 -4906.0
ATG5 -4950.0
PLCG1 -4968.0
CPPED1 -5009.0
COLEC10 -5018.0
TAB2 -5041.0
CASP2 -5043.0
BPIFB4 -5060.0
DSP -5072.0
USP18 -5104.0
DDX41 -5116.0
NCSTN -5119.0
DYNC1H1 -5136.0
CD19 -5138.0
CARD11 -5140.0
NOS2 -5167.0
SLCO4C1 -5181.0
IFNA2 -5215.0
FGB -5252.0
MASP2 -5275.0
EPPIN-WFDC6 -5311.0
PTPN4 -5314.0
ATP8A1 -5380.0
SFTPA1 -5398.0
IRF3 -5401.0
CLEC4D -5414.0
IQGAP1 -5421.0
BPI -5428.0
PSMD1 -5434.0
TXNIP -5484.0
JUN -5493.0
PLCG2 -5512.0
SEMG1 -5554.0
C5 -5556.0
NFKBIA -5622.0
CHIT1 -5640.0
TAB1 -5743.0
TTR -5794.0
PPP2R5D -5799.0
BPIFB2 -5857.0
RPS6KA5 -5871.0
DEFB132 -5873.0
MME -5895.0
NFATC2 -5911.0
MS4A2 -5965.0
ALDH3B1 -5967.0
ATP6V1C2 -5995.0
PSME1 -5997.0
PPP3CB -6017.0
ALOX5 -6026.0
CAPZA2 -6028.0
PSMB6 -6154.0
EEF1A1 -6174.0
RNASET2 -6200.0
MUC17 -6224.0
EPPIN -6230.0
RPS27A -6304.0
EP300 -6335.0
ERP44 -6341.0
ARPC1A -6350.0
POLR3A -6354.0
C6orf120 -6398.0
MGAM -6409.0
HLA-E -6426.0
HBB -6457.0
PKP1 -6481.0
PYGB -6503.0
A1BG -6552.0
PLA2G2A -6567.0
CHRNB4 -6613.0
COMMD9 -6614.0
PTPN6 -6621.0
VPS35L -6626.0
VCP -6635.0
C1S -6663.0
RAB44 -6694.0
NEU1 -6695.0
SNAP25 -6716.0
ACLY -6731.0
PLA2G6 -6800.0
SIKE1 -6825.0
CYBA -6835.0
MAP2K7 -6871.0
MEF2A -6877.0
ATP6V0A4 -6919.0
C1QB -6950.0
POLR3E -6979.0
PGLYRP3 -6988.0
FCGR2A -7016.0
TRIM56 -7041.0
SERPINA3 -7055.0
MUC4 -7070.0
RAP2B -7186.0
RELB -7198.0
CRACR2A -7201.0
RASGRP4 -7202.0
MYH2 -7248.0
ANPEP -7258.0
CFB -7276.0
AHSG -7280.0
MAPK3 -7281.0
IKBKB -7286.0
PSMD8 -7295.0
C9 -7316.0
TIRAP -7319.0
FCGR3B -7363.0
C4BPB -7379.0
HRAS -7398.0
MUC6 -7403.0
IFNA14 -7430.0
TNFRSF1B -7491.0
VTN -7504.0
PRKDC -7512.0
MUCL1 -7539.0
PTPRN2 -7542.0
RPS6KA2 -7543.0
CD4 -7557.0
LBP -7587.0
MASP1 -7588.0
NFASC -7592.0
SERPINB12 -7593.0
SERPINB3 -7601.0
CRCP -7616.0
MUC3A -7631.0
DEFB134 -7656.0
CANT1 -7685.0
PAK2 -7745.0
LILRB3 -7758.0
CFHR2 -7765.0
DOCK1 -7796.0
SPTAN1 -7825.0
SUGT1 -7843.0
HTN3 -7851.0
MUC16 -7920.0
DSC1 -7921.0
CYFIP2 -7932.0
JUP -7950.0
ATAD3B -7993.0
COLEC11 -8018.0
DEFB136 -8021.0
PFKL -8039.0
RAB4B -8078.0
VAV2 -8143.0
BAIAP2 -8168.0
CLEC6A -8184.0
CKAP4 -8206.0
CD36 -8219.0
CGAS -8263.0
TRAF2 -8333.0
PRSS3 -8389.0
ITPR3 -8429.0
MUC5B -8437.0
EEF2 -8509.0
PPIE -8536.0
IKBKE -8538.0
NLRP4 -8562.0
SIGLEC5 -8565.0
C3 -8607.0
C1QA -8655.0
CARD9 -8656.0
GAA -8666.0
KRT1 -8695.0
CD81 -8770.0
DEFB114 -8771.0
LAMP1 -8793.0
MYO10 -8802.0
ATP11A -8849.0
IFNA8 -8854.0
PLPP4 -8890.0
MAPK9 -8959.0
GUSB -8969.0
NLRC3 -8986.0
NFATC1 -8999.0
ALPK1 -9031.0
S100A7 -9091.0
DEFB135 -9097.0
CCR6 -9111.0
DEFB129 -9133.0
MUC20 -9134.0
CASP4 -9205.0
IFNB1 -9255.0
MBL2 -9277.0
RAB24 -9388.0
CST3 -9464.0
CYFIP1 -9552.0
BPIFA2 -9576.0
CD3G -9602.0
CPN2 -9633.0
CRISP3 -9767.0
CDC34 -9774.0
F2 -9946.0
PDPK1 -10016.0
CALML5 -10081.0
CRP -10136.0
PSMB11 -10167.0
FPR1 -10227.0
MMP8 -10228.0
IFNA5 -10276.0
PECAM1 -10282.0
LAT -10354.0
RIPK1 -10392.0
AOC1 -10423.0
PRKACG -10446.0
IFNA21 -10497.0
BPIFB6 -10539.0
SFTPA2 -10784.0


REACTOME_CELLULAR_RESPONSES_TO_STIMULI

REACTOME_CELLULAR_RESPONSES_TO_STIMULI
1314
set REACTOME_CELLULAR_RESPONSES_TO_STIMULI
setSize 779
pANOVA 5.7e-05
s.dist 0.0848
p.adjustANOVA 0.0187



Top enriched genes

Top 20 genes
GeneID Gene Rank
MIR24-2 10982
MAFG 10830
CDKN2B 10744
MT2A 10662
MTF1 10569
CASTOR1 10560
ERN1 10538
MEF2D 10534
PREB 10489
DDIT3 10329
MDM4 10271
GSTP1 10237
RPL37 10222
ARNT 10130
PSMA1 10043
ATF4 10029
CCL2 10003
AGO1 9963
P4HB 9931
CALR 9928

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MIR24-2 10982.0
MAFG 10830.0
CDKN2B 10744.0
MT2A 10662.0
MTF1 10569.0
CASTOR1 10560.0
ERN1 10538.0
MEF2D 10534.0
PREB 10489.0
DDIT3 10329.0
MDM4 10271.0
GSTP1 10237.0
RPL37 10222.0
ARNT 10130.0
PSMA1 10043.0
ATF4 10029.0
CCL2 10003.0
AGO1 9963.0
P4HB 9931.0
CALR 9928.0
H2BC5 9922.0
H3-3A 9850.0
HSBP1 9807.0
CDKN2D 9792.0
CREB3L4 9787.0
NCF2 9776.0
CREB3L3 9775.0
RBX1 9765.0
RPL23 9710.0
RPL35A 9690.0
RPS6KA1 9650.0
NLRP3 9638.0
PSMA6 9587.0
H3C6 9586.0
HSPA6 9572.0
PSMB10 9558.0
PRKCD 9555.0
DCTN2 9498.0
HSP90B1 9489.0
TUBB8 9475.0
H4C5 9463.0
SHC1 9449.0
CSNK2A1 9436.0
DNAJC7 9421.0
XBP1 9400.0
HSPA2 9397.0
RPS28 9388.0
SOD3 9313.0
UBC 9309.0
ATP6V0E2 9278.0
NUP155 9225.0
TNRC6C 9134.0
UBE2E1 9109.0
CRTC3 9018.0
RXRA 9014.0
ATP6V1D 8997.0
COX6A1 8978.0
HBA1 8972.0
FKBP5 8971.0
PSMD13 8956.0
CREB3 8916.0
GPX3 8882.0
MAPK14 8871.0
GPX7 8864.0
GPX1 8853.0
VENTX 8806.0
MT1H 8799.0
BACH1 8787.0
ETS2 8786.0
HMGA1 8648.0
CAMK2G 8634.0
FNIP1 8631.0
TRIM21 8622.0
MYDGF 8590.0
MT1G 8587.0
PHC1 8569.0
ATP6V0C 8558.0
MT3 8542.0
DCTN4 8492.0
H2AZ2 8483.0
H4C16 8472.0
HSPB8 8471.0
ADD1 8465.0
HSPA5 8402.0
TUBA1A 8351.0
H1-3 8345.0
POM121 8341.0
CREB3L2 8336.0
PTK6 8335.0
LAMTOR5 8305.0
CTDSP2 8300.0
CHD9 8289.0
HBA2 8285.0
CRYAB 8277.0
ASNS 8236.0
BLVRB 8230.0
PSMB7 8153.0
RPS29 8130.0
RRAGC 8126.0
ELOC 8110.0
MT1E 8075.0
TXN 8058.0
TUBB2B 8038.0
H4C3 8034.0
SCO2 7917.0
RPS27L 7878.0
NUP85 7856.0
HIF1A 7846.0
SESN2 7821.0
H2BC10 7803.0
RPL14 7799.0
H2AZ1 7791.0
DEDD2 7769.0
COX5A 7752.0
BRCA1 7745.0
HSPA1A 7743.0
ATP6V1G1 7733.0
COX7C 7723.0
RPL37A 7721.0
H2BC6 7626.0
RRAGD 7614.0
MRPL18 7545.0
LAMTOR1 7542.0
ATP6V1E1 7537.0
RPS19BP1 7533.0
FOS 7498.0
ANAPC16 7483.0
TLR4 7476.0
RPL15 7418.0
IGFBP1 7413.0
RPS25 7391.0
BLVRA 7345.0
EIF2S1 7331.0
NUP93 7294.0
H4C13 7291.0
HSPH1 7287.0
AJUBA 7251.0
CDKN2A 7234.0
TNRC6B 7207.0
H1-4 7174.0
CBX4 7076.0
MT1A 7041.0
RPL22L1 6979.0
RPA2 6972.0
UBE2S 6957.0
DIS3 6935.0
RPL41 6881.0
ATP6V1B2 6875.0
CDKN1A 6874.0
SYVN1 6863.0
MT1M 6821.0
WIPI1 6817.0
RPL38 6795.0
UBB 6789.0
NUP43 6787.0
RPL5 6723.0
KAT5 6721.0
BAG5 6715.0
NPLOC4 6645.0
UBXN7 6612.0
PGD 6610.0
HIF3A 6609.0
E2F3 6550.0
KDM6B 6466.0
RPL17 6445.0
CAMK2D 6412.0
ID1 6402.0
IL6 6398.0
PSMB4 6341.0
MT1X 6326.0
RPS8 6323.0
CLEC1B 6305.0
HSPB2 6250.0
HSP90AB1 6186.0
SOD1 6156.0
DYNC1I2 6154.0
GPX2 6120.0
TXNRD1 6118.0
LIMD1 6112.0
CUL1 6104.0
SKP2 6091.0
GSTA1 6060.0
LMNB1 6057.0
H4C8 6054.0
RPL32 6049.0
ETS1 6015.0
SCMH1 6012.0
SEH1L 6001.0
PHC3 5985.0
GSK3B 5966.0
NUP88 5943.0
HSPB1 5926.0
PPP2R5B 5914.0
TUBB4B 5904.0
CCNA2 5893.0
H4C2 5861.0
LAMTOR3 5852.0
SLC46A1 5810.0
EPO 5794.0
RPS9 5759.0
H3C8 5730.0
PSMD12 5712.0
CAT 5678.0
CA9 5654.0
IDH1 5637.0
PSMD3 5632.0
LMNA 5585.0
DCP2 5583.0
RPL34 5563.0
PSME3 5531.0
NUP133 5513.0
PSMB1 5505.0
FKBP14 5470.0
RRAGA 5464.0
DNAJC3 5445.0
NRIP1 5378.0
ATP6V0D2 5348.0
KLHDC3 5343.0
HSPA4L 5326.0
PSMA3 5324.0
DCTN1 5314.0
MLST8 5299.0
MAP3K5 5292.0
PSMC1 5255.0
HSPA14 5190.0
EDEM1 5166.0
NUP42 5142.0
PSMA2 5121.0
STAT3 5078.0
TUBB1 5046.0
CREB3L1 5028.0
EXOSC7 4999.0
RPL31 4979.0
ATP6V1C1 4973.0
PSMC3 4952.0
ATP6V1A 4948.0
H2BC21 4942.0
YIF1A 4917.0
NFYB 4893.0
USP46 4831.0
SQSTM1 4813.0
RPS16 4781.0
H4C1 4741.0
HSPA13 4695.0
RPS24 4646.0
H2AX 4640.0
BMT2 4534.0
SP1 4521.0
H3C1 4493.0
ANAPC7 4462.0
PSMC4 4459.0
CDK4 4448.0
HM13 4410.0
PPP1R15A 4392.0
H2BC8 4336.0
NUDT2 4324.0
HIGD1A 4305.0
COX4I1 4271.0
ANAPC10 4249.0
RANBP2 4242.0
BAG1 4190.0
IGFBP7 4156.0
GOSR2 4150.0
TGS1 4141.0
H1-1 4131.0
TACO1 4122.0
COX8A 4100.0
PPARGC1A 4072.0
CDC16 4071.0
NCOA2 4037.0
BAG4 4036.0
TALDO1 4022.0
DYNLL1 4014.0
CDC26 3998.0
PSMA7 3991.0
MAP2K6 3981.0
RPL28 3944.0
RAI1 3899.0
EXOSC9 3893.0
RPL13 3854.0
MBTPS1 3845.0
CCNA1 3809.0
RBBP4 3683.0
GPX8 3680.0
PSMD14 3675.0
CUL3 3602.0
COX16 3575.0
DNAJB11 3573.0
DNAJA2 3514.0
RPL11 3513.0
H1-2 3500.0
UBE2D3 3479.0
COX18 3478.0
HSPA9 3464.0
ACD 3449.5
RPA3 3436.0
PALB2 3433.0
ATF5 3413.0
RPL24 3384.0
MDM2 3366.0
EED 3280.0
RPS27 3238.0
CAPZA1 3188.0
ANAPC15 3151.0
TNIK 3096.0
CSNK2B 3095.0
HSPA8 3085.0
KICS2 3084.0
H2AC20 3065.0
FNIP2 3064.0
RPS15A 3050.0
TFDP2 3041.0
NBN 2994.0
ATM 2939.0
PRDX6 2907.0
RPS19 2895.0
CDK2 2846.0
CDK6 2832.0
DDX11 2799.0
FAU 2743.0
ZBTB17 2741.0
RPL36AL 2699.5
RNF2 2693.0
NR1D1 2687.0
PRDX2 2680.0
PSMC5 2665.0
RPL12 2663.0
E2F2 2659.0
EXTL2 2581.0
CDKN2C 2548.0
MAPK10 2410.0
EIF2AK3 2332.0
COX19 2299.0
BMAL1 2297.0
BAG3 2283.0
ATP6V1F 2265.0
RPS12 2251.0
CSRP1 2209.0
LRPPRC 2184.0
UBE2C 2145.0
TUBB4A 2142.0
NCOR1 2083.0
DYNC1LI1 2058.0
ACADVL 2024.0
SERP1 2016.0
UBA52 2012.0
H2BC11 1957.0
CDC23 1948.0
NFE2L2 1942.0
GCLC 1903.0
H1-0 1896.0
ATOX1 1811.0
ABCC1 1800.0
KHSRP 1779.0
RPL27 1763.0
RPS20 1739.0
GML 1724.0
H3C2 1718.0
PSME4 1702.0
LAMTOR2 1697.0
MAP1LC3B 1668.0
EXTL1 1651.0
NCOA6 1636.0
RPS13 1623.0
H2AC8 1597.0
DEPDC5 1593.0
TLN1 1585.0
PSME2 1571.0
TUBA8 1559.0
ATP6V1G3 1556.0
TUBA3D 1555.0
MAP4K4 1536.0
COX6B1 1526.0
GSTA3 1518.0
APOA1 1486.0
MAP2K4 1464.0
TPP1 1452.0
SESN1 1418.0
AKT1S1 1387.0
H2AC6 1359.0
HMOX1 1310.0
RAD50 1302.0
ATF3 1301.0
NUP54 1296.0
EGLN1 1265.0
AKT3 1256.0
MAPK8 1248.0
RAE1 1241.0
TUBB6 1236.0
CBX2 1223.0
RPL7 1149.0
RPL9 1142.0
RPS26 1136.0
RPLP1 1131.0
H4C11 1113.0
RPS5 1110.0
MEF2C 1109.0
ERF 1083.0
RPS3A 1022.0
RPL36 1009.0
SSR1 984.0
RPL3L 937.0
POT1 927.0
RPS11 901.0
SLC38A9 889.0
H2BC13 881.0
RPL22 828.0
H2BC9 814.5
H3C7 814.5
RPS21 768.0
NR3C1 760.0
COX6C 721.0
COX11 710.0
RPA1 693.0
PARN 674.0
VHL 650.0
PSMD7 646.0
PSMD6 620.0
NDC1 596.0
EXOSC4 586.0
NCF4 569.0
PSMB3 544.0
MRE11 513.0
ANAPC4 511.0
HDGF 508.0
HIF1AN 430.0
CREB1 418.0
AQP8 409.0
ATP6V0E1 406.0
TXN2 377.0
SEM1 292.0
MYC 235.0
DPP3 216.0
BAG2 135.0
NOX4 123.0
RPL21 81.0
ATF6 75.0
SKP1 51.0
HIRA 49.0
RB1 37.0
EIF2S2 20.0
YWHAE -5.0
NUP37 -104.0
GPX6 -108.0
RPL18 -134.0
SIN3A -157.0
GRB10 -177.0
RPL19 -184.0
CEBPG -195.0
NUP160 -214.0
EXOSC5 -224.0
H2BC15 -242.0
CXCL8 -272.0
PSMC6 -296.0
MAPKAPK3 -304.0
H2BC17 -329.0
EZH2 -340.0
MAPK1 -343.0
GCLM -359.0
PSMA4 -401.0
KEAP1 -423.0
PSMD11 -439.0
DYNLL2 -462.0
GSR -469.0
H2BC3 -494.0
PSMD2 -547.0
COX14 -553.0
ANAPC1 -605.0
PSMB2 -611.0
PSMA8 -621.0
TNFRSF21 -629.0
CSNK2A2 -630.0
DCTN6 -666.0
H2BC12 -702.0
RPS18 -732.0
NFYC -782.0
BMI1 -808.0
PSMD5 -828.0
WDR59 -854.0
H3-3B -861.0
PSMF1 -878.0
ATP6V0B -915.0
SLC7A11 -949.0
ACTR10 -971.0
HSPA1L -995.0
NFYA -1006.0
NUP214 -1024.0
CHAC1 -1038.0
HMGA2 -1070.0
TERF2IP -1191.0
MAP2K3 -1194.0
RPS10 -1200.0
PRDX1 -1220.0
PSMB8 -1223.0
NUP62 -1286.0
TBL1XR1 -1303.0
NCOR2 -1309.0
RORA -1311.0
TATDN2 -1347.0
FBXL17 -1351.0
SOD2 -1414.0
H3C3 -1449.0
TKT -1527.0
RELA -1562.0
DYNC1I1 -1591.0
H3C12 -1618.0
PSMD4 -1623.0
ME1 -1670.0
STAP2 -1709.0
MED1 -1730.0
RPL10A -1739.0
EXTL3 -1795.0
PSMA5 -1800.0
PDIA6 -1848.0
DCTN5 -1855.0
DNAJC2 -1879.0
PGR -1899.0
NOTCH1 -1962.0
XPO1 -1967.0
MAPK7 -2007.0
ATP6V1H -2038.0
RPL35 -2041.0
H2BC26 -2049.0
DNAJB1 -2107.0
NDUFA4 -2120.0
APOB -2139.0
H4C4 -2154.0
ATP6V1E2 -2176.0
NUP58 -2200.0
ELOB -2229.0
RPL6 -2236.0
CDKN1B -2241.0
PSMD9 -2254.0
E2F1 -2318.0
RPS7 -2349.0
MUL1 -2387.0
EGLN3 -2388.0
RPS6 -2392.0
TUBA4A -2409.0
HIKESHI -2428.0
ANAPC5 -2444.0
BTRC -2464.0
SNCB -2473.0
IMPACT -2478.0
CREBBP -2481.0
HELZ2 -2484.0
EXOSC3 -2512.0
PSMB5 -2516.0
DNAJA4 -2564.0
TXNRD2 -2585.0
NUP98 -2594.0
CDC27 -2609.0
DNAJA1 -2615.0
PRDX5 -2641.0
SRPRB -2697.0
NUP188 -2702.0
NUP205 -2719.0
TUBA1B -2722.0
HDAC3 -2760.0
RPL26 -2773.0
H2BC14 -2790.0
NUP210 -2808.0
H3C10 -2825.0
ARFGAP1 -2829.0
MAPKAPK2 -2865.0
TCIRG1 -2874.0
ATP6V1G2 -2939.0
HERPUD1 -2943.0
H2AJ -2954.0
NUP153 -2967.0
H2BC4 -3017.0
ATF2 -3071.0
MAFK -3078.0
ERO1A -3094.0
RPL27A -3107.0
FZR1 -3151.0
LY96 -3154.0
STIP1 -3157.0
AGO3 -3181.0
TP53 -3217.0
CCNE2 -3238.0
RING1 -3254.0
TUBA4B -3318.0
ASF1A -3319.0
CAPZA3 -3349.0
MAPK11 -3380.0
HSPA1B -3482.0
UBE2D2 -3526.0
CITED2 -3552.0
RPL4 -3582.0
DNAJB6 -3613.0
CBX8 -3628.0
ACTR1A -3629.0
RPL23A -3634.0
IL1A -3636.0
RHEB -3638.0
GPX5 -3689.0
CYCS -3692.0
RPL8 -3745.0
H3C11 -3750.0
TUBB3 -3761.0
ATP6V0D1 -3765.0
SEC31A -3800.0
TINF2 -3811.0
PPARA -3818.0
GFPT1 -3828.0
DYNC1LI2 -3832.0
PSMB9 -3852.0
MINK1 -3872.0
UBE2D1 -3873.0
HMOX2 -3881.0
ATR -3882.0
PHC2 -3896.0
AGO4 -3899.0
PTGES3 -3900.0
NFKB1 -3915.0
CABIN1 -3923.0
COX20 -3971.0
CXXC1 -4210.0
AAAS -4247.0
SMARCD3 -4285.0
HSPA4 -4349.0
EIF2AK1 -4377.0
PSMC2 -4425.0
RPL26L1 -4465.0
ATP6V1B1 -4499.0
CARM1 -4597.0
NR3C2 -4604.0
TERF2 -4649.0
NOX5 -4699.0
H2AC4 -4720.0
CUL2 -4726.0
GSK3A -4733.0
SIRT1 -4778.0
HSP90AA1 -4827.0
TFDP1 -4875.0
RPL3 -4879.0
EHMT1 -4884.0
POM121C -4889.0
ST13 -4939.0
RPLP0 -4954.0
ITFG2 -4970.0
CBX6 -4979.0
CLOCK -4981.0
RPSA -4998.0
RPTOR -5084.0
EXOSC8 -5087.0
DYNC1H1 -5136.0
H4C12 -5159.0
NUP35 -5161.0
PRDX3 -5174.0
EXOSC6 -5221.0
ANAPC11 -5234.0
RPS14 -5236.0
NPRL2 -5323.0
EXOSC2 -5329.0
RPL39L -5346.0
H4C6 -5374.0
VEGFA -5384.0
NQO1 -5433.0
PSMD1 -5434.0
CAMK2B -5445.0
AKT1 -5452.0
MIOS -5455.0
TXNIP -5484.0
JUN -5493.0
NUP107 -5699.0
RPS15 -5723.0
RPS3 -5759.0
TNRC6A -5770.0
RPLP2 -5885.0
TUBA1C -5926.0
H2AC18 -5961.5
H2AC19 -5961.5
ATP6V1C2 -5995.0
PSME1 -5997.0
CAPZA2 -6028.0
MAPKAPK5 -6037.0
EPAS1 -6040.0
NUP50 -6058.0
H2BC1 -6085.0
FKBP4 -6098.0
H2AC14 -6099.0
PSMB6 -6154.0
EEF1A1 -6174.0
RPL18A -6198.0
RPS27A -6304.0
UBN1 -6308.0
NCOA1 -6320.0
EP300 -6335.0
COX5B -6340.0
SRPRA -6353.0
ALB -6375.0
DCSTAMP -6410.0
HBB -6457.0
MOV10 -6482.0
NPRL3 -6510.0
CEBPB -6536.0
WTIP -6583.0
VCP -6635.0
UFD1 -6651.0
SRXN1 -6655.0
EGLN2 -6664.0
RPL30 -6692.0
HSF1 -6777.0
EIF2AK4 -6778.0
CYBA -6835.0
H1-5 -6844.0
EHMT2 -6860.0
MAP2K7 -6871.0
KDELR3 -6882.0
H3C4 -6893.0
RLN1 -6912.0
PDIA5 -6923.0
EXOSC1 -6949.0
MIR24-1 -7019.0
SERPINH1 -7183.0
CAPZB -7190.0
CCAR2 -7224.0
TERF1 -7249.0
AKT2 -7272.0
MAPK3 -7281.0
PSMD8 -7295.0
CREBRF -7302.0
SUZ12 -7327.0
HSPA12B -7480.0
DNAJB9 -7488.0
HSPA12A -7524.0
RPS6KA2 -7543.0
RPL29 -7577.0
LAMTOR4 -7644.0
RPS23 -7689.0
RPL7A -7724.0
WFS1 -7757.0
CRTC1 -7780.0
SZT2 -7783.0
H2AC7 -7834.5
H2BC7 -7834.5
MTOR -7846.0
CCNE1 -7915.0
TPR -7967.0
CRTC2 -8156.0
H4C9 -8211.0
TUBAL3 -8254.0
COX7A2L -8264.0
SCO1 -8311.0
MT1F -8436.0
FLCN -8443.0
WDR24 -8503.0
KPTN -8549.0
EP400 -8593.0
CCS -8611.0
PLA2G4B -8652.0
CRYBA4 -8694.0
SH3BP4 -8869.0
RPL13A -8873.5
HYOU1 -8913.0
MAPK9 -8959.0
RPL10L -8965.0
FABP1 -8995.0
CUL7 -9037.0
SURF1 -9100.0
TUBA3C -9110.0
ANAPC2 -9112.0
RPS2 -9117.0
IFNB1 -9255.0
TRIB3 -9275.0
SEC13 -9284.0
NPAS2 -9358.0
SIN3B -9365.0
H3-4 -9417.0
GCN1 -9489.0
MT1B -9524.0
DCTN3 -9549.0
TUBB2A -9660.0
MT4 -9744.0
CAMK2A -9831.0
TUBA3E -9898.0
PSMB11 -10167.0


REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION
1161
set REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION
setSize 1336
pANOVA 8.17e-05
s.dist 0.0642
p.adjustANOVA 0.0224



Top enriched genes

Top 20 genes
GeneID Gene Rank
ZNF676 11136
SFN 11067
MIR24-2 10982
SPI1 10962
ZNF596 10881
MIR27A 10844
NFE2 10755
CDKN2B 10744
ZNF710 10693
MAML1 10669
RYBP 10575
AGRP 10543
ELF1 10542
ZNF689 10504
POU4F2 10453
POMC 10392
NR4A2 10387
SP7 10350
POLR2J 10348
DDIT3 10329

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ZNF676 11136.0
SFN 11067.0
MIR24-2 10982.0
SPI1 10962.0
ZNF596 10881.0
MIR27A 10844.0
NFE2 10755.0
CDKN2B 10744.0
ZNF710 10693.0
MAML1 10669.0
RYBP 10575.0
AGRP 10543.0
ELF1 10542.0
ZNF689 10504.0
POU4F2 10453.0
POMC 10392.0
NR4A2 10387.0
SP7 10350.0
POLR2J 10348.0
DDIT3 10329.0
MDM4 10271.0
NPY 10216.0
RETN 10189.0
ARNT 10130.0
KMT5A 10116.0
ZNF385A 10114.0
ZNF701 10097.0
TP53INP1 10050.0
TNFRSF10B 10045.0
PSMA1 10043.0
ZNF208 10027.0
FOXG1 10022.0
NDRG1 9985.0
BTG2 9976.0
AGO1 9963.0
H2BC5 9922.0
ZNF730 9911.0
THRA 9908.0
ZNF564 9906.0
CTSV 9903.0
ZNF641 9900.0
RGCC 9866.0
H3-3A 9850.0
ZNF658 9837.0
GEM 9829.0
ZNF716 9789.0
GRIA2 9788.0
RXRG 9785.0
RBX1 9765.0
ZNF415 9764.0
CTSK 9728.0
ZNF214 9661.0
RARA 9656.0
DDB2 9641.0
MYB 9626.0
PSMA6 9587.0
H3C6 9586.0
ITGA5 9566.0
PSMB10 9558.0
VDR 9550.0
ZNF860 9470.0
ZKSCAN4 9465.0
H4C5 9463.0
ZNF839 9448.0
CSNK2A1 9436.0
MED7 9385.0
GTF2H4 9368.0
SMARCD2 9360.0
ZNF454 9321.0
UBC 9309.0
SYMPK 9272.0
MED17 9261.0
SYT10 9251.0
CBX5 9245.0
MAGOH 9167.0
HDAC5 9140.0
TNRC6C 9134.0
CHEK2 9124.0
ZNF470 9121.0
YWHAG 9119.0
UBE2E1 9109.0
ZNF560 9098.0
ZNF614 9072.0
ZNF677 9051.0
ZNF418 9032.0
RXRA 9014.0
RNU11 9012.0
SKIC8 8980.0
COX6A1 8978.0
FKBP5 8971.0
PSMD13 8956.0
NR1H3 8932.0
TBX5 8920.0
ZNF706 8909.0
TP53RK 8879.0
MAPK14 8871.0
ZNF224 8866.0
ZNF684 8858.0
PITX2 8838.0
PIP4P1 8835.0
ZNF595 8831.0
IL2RA 8825.0
GAD2 8823.0
VENTX 8806.0
SOX9 8791.0
SUPT16H 8758.0
AURKB 8750.0
ZNF471 8740.0
THOC5 8695.0
NLRC4 8689.0
ZNF792 8661.0
KIT 8660.0
ARID3A 8647.0
CAMK2G 8634.0
MGA 8605.0
ZNF79 8594.0
PHC1 8569.0
MED31 8556.0
OCLN 8553.0
NOTCH2 8539.0
GTF2E1 8518.0
ZNF625 8512.0
H2AZ2 8483.0
H4C16 8472.0
NKX2-5 8454.0
PPARD 8450.0
TFAP2A 8431.0
PPARG 8392.0
EAF2 8368.0
NR5A1 8361.0
TAF12 8360.0
NPAS4 8352.0
TAF15 8316.0
ZNF446 8313.0
LAMTOR5 8305.0
GATAD2B 8274.0
TAF10 8273.0
ZC3H8 8255.0
DDX39B 8252.0
NR2E1 8210.0
CASP6 8201.0
CHEK1 8188.0
PSMB7 8153.0
ZNF175 8139.0
RRAGC 8126.0
ELOC 8110.0
POLR2K 8079.0
ZNF442 8066.0
TXN 8058.0
CASP10 8044.0
SMARCA2 8040.0
H4C3 8034.0
ZNF230 8011.0
SOX2 8009.0
LSM10 7985.0
PPP1R13L 7969.0
ZNF143 7952.0
CCNH 7926.0
CCNT2 7921.0
SCO2 7917.0
POLR2G 7915.0
RBBP8 7903.0
TCF12 7895.0
PPM1A 7869.0
LDB1 7864.0
ZNF223 7849.0
TBP 7840.0
ZNF548 7827.0
SESN2 7821.0
H2BC10 7803.0
H2AZ1 7791.0
BMP2 7789.0
DEK 7768.0
COX5A 7752.0
BRCA1 7745.0
ZNF225 7738.0
BGLAP 7736.0
COX7C 7723.0
GTF2H3 7687.0
ZNF621 7669.0
BCL2L14 7659.0
ZC3H11A 7657.0
ZNF304 7640.0
H2BC6 7626.0
RRAGD 7614.0
ZNF443 7591.0
NR2F1 7581.0
CR1 7561.0
ZNF155 7551.0
LAMTOR1 7542.0
GATA4 7532.0
ZNF582 7529.0
CRADD 7524.0
FOS 7498.0
ZNF680 7496.0
ANAPC16 7483.0
CNOT6L 7441.0
IGFBP1 7413.0
YWHAZ 7406.0
ZNF233 7378.0
RNF111 7377.0
ZNF607 7366.0
ELL3 7365.0
NKX3-2 7348.0
H4C13 7291.0
E2F5 7288.0
CDKN2A 7234.0
ZNF432 7232.0
THOC6 7214.0
TNRC6B 7207.0
BBC3 7198.0
AFF4 7182.0
CSF2 7180.0
SLU7 7178.0
KAT6A 7094.0
CBX4 7076.0
ZNF649 7066.0
ZNF692 7057.0
ZNF589 7056.0
ZNF235 7049.0
IL2 7028.0
ZNF519 7019.0
PBRM1 7017.0
ZNF566 7012.0
SST 6983.0
TAF2 6977.0
RPA2 6972.0
UBE2S 6957.0
ZNF790 6933.0
UCMA 6932.0
ZNF571 6911.0
TRIM63 6891.0
SARNP 6876.0
CDKN1A 6874.0
ZNF540 6840.0
POU2F1 6818.0
UBB 6789.0
APOE 6788.0
ZNF776 6786.0
ZNF211 6770.0
SNRPF 6766.0
ZNF599 6741.0
KAT5 6721.0
ZNF136 6718.0
RBM8A 6706.0
BTG1 6683.0
REST 6679.0
SSRP1 6669.0
GLS2 6625.0
KRAS 6597.0
SGK1 6578.0
ZNF552 6563.0
TP53BP2 6552.0
ZNF568 6544.0
TGIF2 6540.0
SMARCC2 6513.0
CASP1 6508.0
CPSF3 6505.0
ZNF561 6480.0
ZNF350 6459.0
RORB 6425.0
ZNF791 6420.0
CAMK2D 6412.0
BRIP1 6400.0
IL6 6398.0
ZNF660 6377.0
GTF2H1 6356.0
BNIP3L 6353.0
PSMB4 6341.0
SMURF2 6337.0
SMAD7 6329.0
ZNF226 6294.0
TPX2 6287.0
GATAD2A 6286.0
SRF 6273.0
PRKACA 6257.0
SMAD3 6244.0
CLDN5 6220.0
ZNF20 6176.0
ZNF729 6149.0
PML 6123.0
GPX2 6120.0
TXNRD1 6118.0
CUL1 6104.0
SKP2 6091.0
H4C8 6054.0
ZNF740 6034.0
NR1I2 6029.0
DLX5 6014.0
SCMH1 6012.0
ZNF565 5998.0
PCGF6 5987.0
PHC3 5985.0
PRDM1 5983.0
IWS1 5976.0
GSK3B 5966.0
MED20 5939.0
NUDT21 5931.0
ZNF770 5927.0
PRMT1 5915.0
CCNA2 5893.0
YBX1 5890.0
PVALB 5877.0
ZNF727 5868.0
PTPN1 5864.0
H4C2 5861.0
LAMTOR3 5852.0
CDK13 5829.0
RRM2B 5824.0
ZNF667 5800.0
ZNF420 5789.0
TAF6 5764.0
ZNF709 5751.0
H3C8 5730.0
PSMD12 5712.0
CNOT8 5687.0
TWIST1 5681.0
CAT 5678.0
DLX6 5675.0
PPARGC1B 5659.0
PSMD3 5632.0
HDAC10 5600.0
PHF20 5589.0
PRKAG3 5577.0
USP2 5562.0
PSME3 5531.0
PSMB1 5505.0
ZNF569 5473.0
RRAGA 5464.0
ZNF77 5455.0
TP53I3 5432.0
ZNF559 5414.0
MIR132 5401.0
SOCS4 5386.0
MED8 5377.0
SRSF7 5362.0
CITED4 5356.0
PPP2R5C 5344.0
PSMA3 5324.0
SRC 5308.0
MLST8 5299.0
ZNF266 5297.0
RAD9B 5280.0
ZNF567 5276.0
ZNF14 5264.0
RUNX1 5262.0
PSMC1 5255.0
SUPT4H1 5232.0
SLBP 5223.0
TAF5 5215.0
RBBP5 5200.0
DAXX 5185.0
SMARCD1 5172.0
ZNF510 5162.0
ZNF585A 5151.0
ZKSCAN5 5145.0
NABP2 5124.0
PSMA2 5121.0
ZNF461 5116.0
CPSF6 5101.0
ZNF337 5080.0
PLAGL1 5077.0
SMARCE1 5061.0
RPAP2 5050.0
RORC 5048.0
ZNF479 5047.0
CDC7 5034.0
MED25 4997.0
INTS3 4988.0
PSMC3 4952.0
ZNF347 4951.0
ZNF124 4945.0
H2BC21 4942.0
NFYB 4893.0
HIVEP3 4879.0
ZNF254 4872.0
HDAC2 4870.0
HNF4A 4868.0
ZNF215 4840.0
TFAP2C 4819.0
LGALS3 4818.0
SATB2 4807.0
ZNF786 4797.0
INTS9 4787.0
CALM1 4775.0
ZNF669 4752.0
H4C1 4741.0
TAF9 4726.0
ZNF624 4721.0
HSPD1 4718.0
HDAC11 4705.0
ZNF775 4694.0
CDC25C 4680.0
LMO2 4668.0
SPP1 4654.0
H2AX 4640.0
LBR 4632.0
NOP2 4600.0
ZNF25 4589.0
ZNF620 4588.0
BCL2L11 4581.0
NR4A3 4580.0
ZNF343 4566.0
PCF11 4555.0
CRH 4549.0
SP1 4521.0
H3C1 4493.0
POLR2C 4490.0
TGIF1 4485.0
BLM 4469.0
ANAPC7 4462.0
PSMC4 4459.0
CDK4 4448.0
GTF2B 4439.0
ZNF140 4429.0
ZNF180 4427.0
FBXO32 4416.0
SETD1A 4378.0
NELFB 4377.0
POU2F2 4373.0
CLP1 4372.0
ZNF285 4344.0
H2BC8 4336.0
RAD9A 4283.0
PAPOLA 4282.0
COX4I1 4271.0
ACTL6B 4254.0
FANCC 4252.0
ANAPC10 4249.0
ITGA2B 4246.0
CNOT10 4171.0
ZNF274 4169.0
ZNF562 4164.0
TEAD2 4148.0
ZNF70 4138.0
TACO1 4122.0
ZNF496 4118.0
ZNF688 4101.0
COX8A 4100.0
CDK12 4098.0
RARG 4080.0
PPARGC1A 4072.0
CDC16 4071.0
RFC4 4043.0
ZNF670 4026.0
FANCI 4015.0
SMURF1 4010.0
CDC26 3998.0
ZNF99 3996.0
PSMA7 3991.0
MAP2K6 3981.0
ZNF681 3976.0
RARB 3970.0
HAND2 3875.0
SRRT 3859.0
ZNF530 3856.0
ZNF189 3843.0
NR2C2AP 3842.0
CCNA1 3809.0
CDC73 3806.0
RBFOX1 3770.0
MED24 3752.0
MLLT3 3748.0
TFAP2E 3711.0
RBBP4 3683.0
PSMD14 3675.0
ZNF490 3670.0
MED30 3669.0
INTS8 3664.0
EPC1 3661.0
CCNB1 3644.0
ASH2L 3621.0
COX16 3575.0
ZNF154 3546.0
ZNF133 3524.0
RNU12 3498.0
RMI2 3488.0
UBE2D3 3479.0
COX18 3478.0
POLR2D 3460.0
INTS2 3451.0
ARID1B 3440.0
RPA3 3436.0
ZNF738 3410.0
GAMT 3381.0
MDM2 3366.0
SNAPC3 3352.0
TGFA 3350.0
TEAD3 3321.0
KMT2E 3290.0
BCL6 3281.0
EED 3280.0
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ARID1A 3269.0
MAPKAP1 3229.0
SNRPD3 3225.0
FOXO3 3206.0
ZNF528 3200.0
ZFP37 3183.0
ATRIP 3175.0
POLR2H 3166.0
MAML2 3161.0
ZNF785 3156.0
ELL2 3153.0
ANAPC15 3151.0
ZNF606 3121.0
CSNK2B 3095.0
SRSF4 3087.0
PRMT6 3081.0
CHD4 3069.0
H2AC20 3065.0
GATA2 3060.0
TFDP2 3041.0
E2F4 3024.0
RBL2 3020.0
PPP2R1B 3019.0
KLF4 3002.0
NBN 2994.0
ERBB2 2972.0
DDX39A 2971.0
ATM 2939.0
ZNF417 2915.0
POLR2L 2911.0
FYTTD1 2888.0
ZNF416 2877.0
ZNF662 2864.0
CDK2 2846.0
CDK6 2832.0
ZNF546 2826.0
RUNX2 2802.0
TTC5 2790.0
ZNF747 2725.0
FOXO1 2702.0
RNF2 2693.0
NR1D1 2687.0
TRIAP1 2684.0
PRDX2 2680.0
PSMC5 2665.0
ZNF257 2661.0
L3MBTL2 2647.0
PMAIP1 2645.0
ZIM2 2593.0
INTS7 2563.0
PCGF5 2562.0
ZNF19 2558.0
CCN2 2553.0
CNOT4 2541.0
SMAD2 2520.0
ZNF584 2478.0
SMAD4 2475.0
ESRRG 2474.0
RBM14 2471.0
POLR2F 2465.0
LMO1 2430.0
TFAP2B 2408.0
MSX2 2402.0
ICE1 2397.0
NR4A1 2388.0
INTS13 2380.0
EXO1 2374.0
SKI 2365.0
PRKAA2 2357.0
RABGGTA 2353.0
ITGA4 2339.0
YEATS4 2318.0
BARD1 2305.0
COX19 2299.0
BMAL1 2297.0
CDK5 2270.0
GAD1 2263.0
CAMK4 2241.0
RNF34 2232.0
MMP13 2198.0
LRPPRC 2184.0
LSM11 2180.0
BDNF 2176.0
MED6 2154.0
TCEA1 2151.0
RPRD2 2146.0
UBE2C 2145.0
RBL1 2141.0
RBPJ 2134.0
ZNF112 2124.0
STUB1 2116.0
ZNF10 2095.0
NCOR1 2083.0
SERPINB13 2057.0
ZNF135 2040.0
G6PC1 2018.0
UBA52 2012.0
CHD3 2001.0
PLK3 1991.0
ABCA6 1977.0
SMARCC1 1973.0
H2BC11 1957.0
CDC23 1948.0
ZNF619 1925.0
GTF2A2 1911.0
CPSF2 1865.0
RAD17 1851.0
TNFRSF10A 1837.0
NABP1 1781.0
ZNF573 1777.0
CCNK 1765.0
H3C2 1718.0
MLH1 1703.0
PSME4 1702.0
LAMTOR2 1697.0
ZNF92 1691.0
PIP4K2C 1689.0
MEAF6 1671.0
NCBP1 1650.0
IHH 1648.0
PCNA 1644.0
ERCC3 1635.0
ZNF331 1604.0
H2AC8 1597.0
FBXW7 1587.0
PSME2 1571.0
PRKAG1 1552.0
COX6B1 1526.0
RHNO1 1516.0
SNAPC1 1501.0
ITGAL 1490.0
PLK2 1439.0
ZNF585B 1437.0
BRD2 1434.0
SESN1 1418.0
TIGAR 1400.0
GTF2F2 1394.0
MYBL2 1386.0
CDC40 1379.0
H2AC6 1359.0
TSC1 1353.0
ZNF664 1335.0
ZNF354B 1334.0
RAD50 1302.0
ZNF543 1286.0
AKT3 1256.0
CBX2 1223.0
SIRT3 1197.0
PPP2R1A 1180.0
H4C11 1113.0
HIPK2 1112.0
MEF2C 1109.0
OPRM1 1089.0
ATXN3 1086.0
ZNF583 1038.0
ZNF726 1001.0
ZNF37A 995.0
HDAC9 990.0
TAF3 983.0
ITCH 944.0
ZFP30 942.0
TAF7 940.0
MED4 907.0
ELF2 903.0
YWHAB 890.0
SLC38A9 889.0
NR2F6 888.0
CTSL 886.0
H2BC13 881.0
ZNF804B 851.0
ZNF333 845.0
MAX 834.0
RXRB 817.0
H2BC9 814.5
H3C7 814.5
TOPBP1 811.0
ZNF749 791.0
CNOT7 781.0
NR3C1 760.0
ZNF287 740.0
GTF2H5 738.0
DDIT4 723.0
COX6C 721.0
ZNF547 717.0
COX11 710.0
THRB 707.0
IGFBP3 698.0
RPA1 693.0
MBD3 675.0
NR6A1 665.0
WDR33 651.0
PSMD7 646.0
ABL1 644.0
CCNC 626.0
PSMD6 620.0
ZIM3 619.0
CASC3 616.0
ZNF436 584.0
RTF1 558.0
PSMB3 544.0
POLDIP3 532.0
SRSF11 531.0
ZKSCAN3 524.0
KCTD1 520.0
ZFP28 514.0
MRE11 513.0
ANAPC4 511.0
YAP1 490.0
ZNF324B 484.0
ZNF771 470.0
PIP4K2A 468.0
ZNF782 452.0
JUNB 420.0
THOC7 419.0
CREB1 418.0
GLS 388.0
ZNF473 385.0
PRKAB2 361.0
ZNF555 358.0
HDAC7 354.0
ZNF480 336.0
ICE2 321.0
CSTF1 296.0
CGB5 294.0
SEM1 292.0
PRMT5 288.0
PRR5 286.0
RPRD1A 270.0
MYC 235.0
MSH2 230.0
POU4F1 206.0
KDM5B 186.0
ZKSCAN1 167.0
ZNF708 159.0
ZNF718 118.0
TP73 82.0
MAML3 55.0
SKP1 51.0
CBX3 50.0
RB1 37.0
ZNF703 33.0
TMEM219 27.0
INTS6 18.0
YWHAE -5.0
MED27 -6.0
LEF1 -54.0
ZNF549 -63.0
TFAP2D -82.0
SETD1B -103.0
ZNF704 -105.0
ZNF440 -118.0
SIN3A -157.0
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MTA2 -172.0
PAF1 -192.0
HUS1 -198.0
MDC1 -207.0
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ZFP69B -235.0
H2BC15 -242.0
PIN1 -261.0
MLLT1 -284.0
U2AF1L4 -292.0
PSMC6 -296.0
ELL -297.0
ZNF777 -298.0
ZNF746 -301.0
PTEN -311.0
GPI -315.0
RICTOR -316.0
NR5A2 -319.0
H2BC17 -329.0
ZNF433 -336.0
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EZH2 -340.0
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TOP3A -380.0
CHTOP -382.0
ZNF570 -392.0
PSMA4 -401.0
GTF2A1 -402.0
PRKCB -426.0
PSMD11 -439.0
MIR137 -455.0
GSR -469.0
ZNF273 -490.0
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CCND3 -517.0
PSMD2 -547.0
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YWHAH -558.0
ZFP90 -575.0
ZNF317 -601.0
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PSMB2 -611.0
PSMA8 -621.0
CSNK2A2 -630.0
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ZNF772 -647.0
TP63 -648.0
ZNF483 -655.0
ZNF699 -676.0
GPS2 -700.0
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ESRRA -715.0
HIPK1 -729.0
NR1I3 -748.0
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SUMO1 -765.0
CSTF3 -777.0
NFYC -782.0
BMI1 -808.0
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SRSF3 -813.0
PF4 -818.0
AIFM2 -821.0
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PSMF1 -878.0
PPP1R13B -913.0
ZNF655 -920.0
RSPO3 -929.0
ZNF222 -988.0
CNOT2 -993.0
NFYA -1006.0
GPAM -1017.0
RFFL -1022.0
BRPF3 -1053.0
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ZNF517 -1148.0
ZNF354C -1159.0
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AURKA -1179.0
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ZNF616 -1192.0
NR1D2 -1201.0
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PSMB8 -1223.0
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ZNF665 -1235.0
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ZNF234 -1270.0
DHX38 -1294.0
MNAT1 -1296.0
TBL1XR1 -1303.0
NCOR2 -1309.0
RORA -1311.0
PPM1D -1329.0
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CCNT1 -1380.0
CDK1 -1393.0
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ZNF557 -1455.0
ZNF682 -1464.0
ZNF551 -1473.0
SMAD1 -1523.0
ZNF764 -1541.0
STK11 -1549.0
RELA -1562.0
UBE2I -1568.0
PAX5 -1571.0
CPSF7 -1578.0
ESR2 -1583.0
PCBP4 -1590.0
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H3C12 -1618.0
PSMD4 -1623.0
SESN3 -1659.0
BID -1669.0
ZNF679 -1691.0
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CAV1 -1744.0
HES1 -1748.0
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THBS1 -1782.0
ZNF554 -1786.0
ZNF45 -1794.0
PSMA5 -1800.0
CTR9 -1807.0
ZNF394 -1815.0
ATAD2 -1816.0
ZNF197 -1822.0
RNMT -1836.0
ZNF382 -1845.0
ITGBL1 -1860.0
SNAPC5 -1880.0
PIDD1 -1890.0
CTNNB1 -1892.0
PGR -1899.0
ZNF587 -1914.0
SNRPG -1929.0
POLR2E -1933.0
ZNF268 -1959.0
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XPO1 -1967.0
ZNF563 -1974.0
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ZNF544 -2069.0
ZNF484 -2072.0
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WWTR1 -2118.0
NDUFA4 -2120.0
BRPF1 -2135.0
H4C4 -2154.0
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CDKN1B -2241.0
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ZNF668 -2278.0
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NCBP2 -2301.0
ZNF75A -2306.0
ZNF250 -2309.0
ZNF221 -2316.0
FIP1L1 -2317.0
E2F1 -2318.0
PRKCQ -2320.0
ZNF74 -2333.0
ZNF615 -2348.0
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RFC2 -2427.0
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ZNF263 -2463.0
CREBBP -2481.0
YWHAQ -2486.0
ZNF2 -2504.0
PSMB5 -2516.0
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EAF1 -2521.0
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ZNF101 -2599.0
CDC27 -2609.0
INTS4 -2623.0
NPM1 -2625.0
TGFB1 -2633.0
ZNF750 -2640.0
PRDX5 -2641.0
RFC3 -2687.0
ZNF426 -2714.0
ZNF248 -2731.0
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H2AJ -2954.0
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H2BC4 -3017.0
ZNF597 -3026.0
OPRK1 -3062.0
ATF2 -3071.0
AUTS2 -3073.0
ZNF169 -3081.0
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TCF7L2 -3124.0
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AXIN1 -3147.0
FZR1 -3151.0
WRN -3171.0
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CCNE2 -3238.0
ZNF398 -3250.0
RING1 -3254.0
ZNF33A -3280.0
SRSF2 -3316.0
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CCND2 -3379.0
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MET -3382.0
ZNF485 -3394.0
CSTF2T -3402.0
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ZNF17 -3453.0
ZNF468 -3491.0
CITED2 -3552.0
PABPN1 -3580.0
ZNF26 -3584.0
PERP -3590.0
KAT2B -3620.0
PPP2CB -3621.0
CBX8 -3628.0
RHEB -3638.0
ZNF577 -3653.0
PPP2CA -3664.0
ZNF441 -3668.0
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ZNF778 -3712.0
ZNF697 -3718.0
ZNF875 -3725.0
ZNF227 -3726.0
ZFP69 -3744.0
H3C11 -3750.0
ZNF713 -3781.0
FAS -3797.0
E2F8 -3815.0
PPARA -3818.0
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ZNF613 -3826.0
TCF7L1 -3831.0
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PSMB9 -3852.0
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SNW1 -3879.0
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ZNF28 -3891.0
PHC2 -3896.0
AGO4 -3899.0
ZNF3 -3912.0
NFKB1 -3915.0
TAL1 -3948.0
COX20 -3971.0
ZNF492 -3973.0
RMI1 -3986.0
TAF4B -3992.0
ZNF721 -4011.0
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ZNF700 -4071.0
BRD7 -4075.0
DYRK2 -4078.0
CDK9 -4087.0
ZNF212 -4100.0
NELFCD -4105.0
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CBFB -4226.0
RET -4257.0
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ZNF300 -4330.0
ZNF793 -4338.0
ZNF160 -4342.0
ZNF253 -4351.0
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JMY -4420.0
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ZNF714 -4433.0
ZNF43 -4437.0
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ZNF529 -4492.0
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ZNF429 -4603.0
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TAF13 -4616.0
ZNF431 -4618.0
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H2AC4 -4720.0
ZNF256 -4760.0
ZNF445 -4765.0
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SIRT1 -4778.0
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ZNF282 -4890.0
ZNF724 -4917.0
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CASP2 -5043.0
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ZNF514 -5085.0
ZNF114 -5101.0
PCK1 -5150.0
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IFNG -5195.0
FANCD2 -5203.0
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ZNF430 -5394.0
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ZNF460 -5525.0
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ZNF586 -5831.0
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ZNF302 -6068.0
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GCK -8489.0
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ARNT2 -8710.0
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ZNF737 -9883.0
TP53AIP1 -9930.0
CTLA4 -9993.0
PDPK1 -10016.0
SNAPC4 -10046.0
ZNF626 -10080.0
PSMB11 -10167.0
ZNF383 -10209.0
KMT2B -10240.0
GLI2 -10326.0
THOC3 -10478.0
ZNF717 -10582.0
FOXO6 -10691.0
CGB8 -10754.0


REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR

REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR
224
set REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR
setSize 11
pANOVA 0.00123
s.dist 0.563
p.adjustANOVA 0.257



Top enriched genes

Top 20 genes
GeneID Gene Rank
TLR9 10408
UNC93B1 10252
CTSV 9903
CTSK 9728
TLR3 9536
HSP90B1 9489
LGMN 6623
CTSB 2023
CTSS 1093
CTSL 886
CNPY3 -60

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TLR9 10408
UNC93B1 10252
CTSV 9903
CTSK 9728
TLR3 9536
HSP90B1 9489
LGMN 6623
CTSB 2023
CTSS 1093
CTSL 886
CNPY3 -60


REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM

REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM
78
set REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM
setSize 688
pANOVA 0.00125
s.dist 0.0722
p.adjustANOVA 0.257



Top enriched genes

Top 20 genes
GeneID Gene Rank
IL27 11126
IFNL2 11102
TNFSF13 11053
PRTN3 11038
CTSG 11021
LGALS9 11011
CCL4 11009
CTF1 10969
CSF3 10953
CLCF1 10866
CCL22 10754
SERPINB2 10719
CCL3 10706
IFNA16 10685
MT2A 10662
IL10 10644
NRAS 10599
IL1B 10591
IL17RE 10550
DUSP3 10526

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
IL27 11126.0
IFNL2 11102.0
TNFSF13 11053.0
PRTN3 11038.0
CTSG 11021.0
LGALS9 11011.0
CCL4 11009.0
CTF1 10969.0
CSF3 10953.0
CLCF1 10866.0
CCL22 10754.0
SERPINB2 10719.0
CCL3 10706.0
IFNA16 10685.0
MT2A 10662.0
IL10 10644.0
NRAS 10599.0
IL1B 10591.0
IL17RE 10550.0
DUSP3 10526.0
TNFRSF1A 10393.0
POMC 10392.0
IFNA1 10388.0
UBA7 10383.0
EIF4G1 10349.0
HGF 10328.0
IFNAR1 10281.0
IFNGR2 10269.0
IRF8 10257.0
SNRPA1 10246.0
LCN2 10211.0
TNFRSF6B 10112.0
GRB2 10092.0
NKIRAS2 10063.0
PSMA1 10043.0
CCL2 10003.0
IFI30 9979.0
IL6R 9975.0
NOD1 9966.0
PIK3R2 9942.0
P4HB 9931.0
PTPRJ 9930.0
ALOX15 9784.0
SAA1 9781.0
CANX 9768.0
RBX1 9765.0
UBE2N 9761.0
IL19 9686.0
TNFSF4 9664.0
RPS6KA1 9650.0
PSMA6 9587.0
H3C6 9586.0
PSMB10 9558.0
PRKCD 9555.0
CD27 9532.0
HSP90B1 9489.0
FCER2 9480.0
IRAK3 9452.0
SHC1 9449.0
IL17C 9440.0
IL1RN 9398.0
PELI3 9344.0
UBC 9309.0
IL26 9257.0
NUP155 9225.0
RHOU 9219.0
IFIT2 9211.0
PIAS1 9172.0
UBE2E1 9109.0
IFNA7 9083.0
IFITM2 9025.0
GSTO1 9004.0
CCR2 9002.0
PSMD13 8956.0
MAP2K1 8942.0
MAPK14 8871.0
KPNA2 8841.0
OASL 8827.0
IL2RA 8825.0
FGF2 8790.0
IRF5 8723.0
CD40 8697.0
THOC5 8695.0
CCL19 8694.0
TNFSF12 8658.0
MMP9 8639.0
CAMK2G 8634.0
TRIM21 8622.0
IL12RB1 8571.0
IFNLR1 8551.0
IL18 8424.0
TNFSF8 8382.0
MAP3K8 8362.0
POM121 8341.0
ANXA1 8271.0
UBE2V1 8231.0
LCK 8208.0
SIGIRR 8194.0
SLA 8167.0
UBE2L6 8158.0
PSMB7 8153.0
ELOC 8110.0
HLA-DQA1 8068.0
SOX2 8009.0
GAB2 7974.0
STX1A 7920.0
NUP85 7856.0
HIF1A 7846.0
CCR1 7845.0
TRIM45 7842.0
BST2 7771.0
MYD88 7749.0
MAP3K14 7646.0
CD86 7642.0
IP6K2 7621.0
IFITM1 7620.0
FOS 7498.0
TRIM14 7457.0
YWHAZ 7406.0
S100B 7344.0
TRIM38 7333.0
HLA-H 7327.0
NUP93 7294.0
TNFRSF13C 7290.0
JAK1 7274.0
NKIRAS1 7269.0
IL11 7206.0
CSF2 7180.0
CRKL 7133.0
MTAP 7131.0
IL23A 7117.0
IL2 7028.0
TRAF6 7001.0
IFNL1 6955.0
IFI35 6922.0
STAT6 6912.0
MAP3K7 6877.0
CDKN1A 6874.0
CIITA 6870.0
ARF1 6868.0
RSAD2 6820.0
POU2F1 6818.0
HCK 6804.0
FBXW11 6800.0
UBB 6789.0
NUP43 6787.0
PELI2 6745.0
B2M 6729.0
GRAP2 6657.0
KRAS 6597.0
CDC42 6585.0
CASP1 6508.0
EIF4E2 6491.0
LTB 6483.0
TNFRSF17 6455.0
IL34 6447.0
TEC 6441.0
LTBR 6432.0
CAMK2D 6412.0
IL6 6398.0
IL21R 6372.0
HAVCR2 6350.0
PSMB4 6341.0
SMAD7 6329.0
TBK1 6319.0
TXLNA 6298.0
CASP8 6261.0
PRKACA 6257.0
RALA 6251.0
SMAD3 6244.0
SOD1 6156.0
IL1RL2 6148.0
LYN 6131.0
PML 6123.0
CUL1 6104.0
SOCS1 6069.0
LMNB1 6057.0
SEH1L 6001.0
HMGB1 5972.0
NUP88 5943.0
NEDD4 5897.0
PTPN1 5864.0
STAT5B 5853.0
TSLP 5770.0
TRIM8 5731.0
H3C8 5730.0
PSMD12 5712.0
CXCL1 5682.0
TWIST1 5681.0
PSMD3 5632.0
PSME3 5531.0
NUP133 5513.0
PSMB1 5505.0
HLA-B 5425.0
PSMA3 5324.0
SRC 5308.0
FLT3 5287.0
PSMC1 5255.0
VAV1 5248.0
MAP3K3 5203.0
BIRC3 5187.0
NUP42 5142.0
PSMA2 5121.0
STAT3 5078.0
HLA-DQA2 5070.0
RORC 5048.0
IL27RA 5029.0
PTK2B 4956.0
PSMC3 4952.0
PTPN18 4947.0
PTPN2 4943.0
TNFSF11 4907.0
CNTFR 4891.0
IL16 4865.0
CXCL10 4844.0
SQSTM1 4813.0
NOD2 4792.0
PPM1B 4714.0
INPP5D 4677.0
TNFRSF9 4664.0
TNFSF13B 4634.0
MUC1 4610.0
LCP1 4604.0
IL12B 4601.0
PELI1 4599.0
BCL2L11 4581.0
USP14 4516.0
H3C1 4493.0
IL20 4481.0
PSMC4 4459.0
PDCD4 4431.0
HLA-DRB1 4417.0
TCP1 4387.0
EIF2AK2 4383.0
TNFSF18 4382.0
BCL2 4375.0
TNFRSF8 4260.0
RANBP2 4242.0
IL33 4203.0
SH2B3 4114.0
IL7 4095.0
TALDO1 4022.0
PSMA7 3991.0
MAP2K6 3981.0
FLT3LG 3928.0
KPNB1 3909.0
CSF1 3905.0
IFI27 3884.0
CSF2RB 3822.0
PIK3R1 3783.0
SOS1 3727.0
PSMD14 3675.0
TNFRSF11A 3674.0
IL20RB 3630.0
IRF1 3625.0
IFIT5 3617.0
CCR5 3606.0
RAP1B 3595.0
PTPN12 3542.0
ICAM1 3541.0
IRF9 3525.0
ITGAM 3504.0
UBE2D3 3479.0
HSPA9 3464.0
EIF4G3 3445.0
SOS2 3404.0
HLA-DQB2 3372.0
IRF7 3360.0
IL4 3345.0
EIF4E 3335.0
BCL6 3281.0
LRRC14 3274.0
KPNA4 3212.0
FOXO3 3206.0
CAPZA1 3188.0
SP100 3154.0
IL4R 3139.0
CCL5 3112.0
IL15 3108.0
OSM 3107.0
HSPA8 3085.0
PTPN7 3048.0
SLA2 3043.0
HLA-DPA1 3042.0
PPP2R1B 3019.0
IL12RB2 2984.0
IL11RA 2962.0
IRAK2 2933.0
IL1RL1 2909.0
CRK 2818.0
TNFRSF11B 2817.0
UBA3 2796.0
SOCS2 2793.0
RAPGEF1 2739.0
IFIT1 2732.0
FOXO1 2702.0
TRIM31 2688.0
IL36G 2673.0
CBL 2669.0
PSMC5 2665.0
IL24 2654.0
IL1R2 2653.0
STAT4 2641.0
OAS2 2582.0
IL10RB 2515.0
SYK 2502.0
ABL2 2421.0
MAPK10 2410.0
F13A1 2404.0
MIF 2231.0
IFNA6 2215.0
IFITM3 2144.0
OSMR 2107.0
RAG2 2015.0
UBA52 2012.0
CD44 1970.0
EIF4A1 1962.0
CSK 1918.0
NFKB2 1809.0
HNRNPA2B1 1788.0
HLA-G 1735.0
H3C2 1718.0
PSME4 1702.0
APP 1659.0
GBP5 1649.0
SAMHD1 1625.0
ABCE1 1589.0
PSME2 1571.0
HNRNPDL 1524.0
VIM 1515.0
HLA-DRA 1488.0
MAP2K4 1464.0
S100A12 1431.0
HERC5 1430.0
NLRC5 1429.0
HLA-DQB1 1323.0
HMOX1 1310.0
NUP54 1296.0
DUSP6 1294.0
AKT3 1256.0
MAPK8 1248.0
RAE1 1241.0
ITGAX 1235.0
IL1R1 1205.0
PPP2R1A 1180.0
MEF2C 1109.0
OPRM1 1089.0
PIM1 1084.0
KPNA7 1044.0
PTAFR 993.0
PTPN9 896.0
H3C7 814.5
BRWD1 805.0
AIP 800.0
EIF4G2 765.0
UBE2M 724.0
PSMD7 646.0
PSMD6 620.0
NDC1 596.0
PSMB3 544.0
IL6ST 500.0
TRAF3 449.0
IL17RB 421.0
JUNB 420.0
CREB1 418.0
IL17RC 362.0
OAS3 348.0
STX3 335.0
EIF4E3 328.0
SEM1 292.0
MYC 235.0
MCL1 185.0
ZEB1 165.0
BIRC2 154.0
IRAK4 129.0
IL17RA 119.0
PIK3CB 107.0
SKP1 51.0
ADAM17 -76.0
NUP37 -104.0
PTPN13 -130.0
PDE12 -140.0
GRB10 -177.0
IFNGR1 -183.0
SH2B1 -185.0
PTPRZ1 -190.0
NUP160 -214.0
EIF4A2 -247.0
PIN1 -261.0
CXCL8 -272.0
IL15RA -295.0
PSMC6 -296.0
MAPKAPK3 -304.0
CNN2 -330.0
MAPK1 -343.0
IL5 -367.0
PSMA4 -401.0
PSMD11 -439.0
PSMD2 -547.0
NFKBIB -565.0
IL18R1 -609.0
PSMB2 -611.0
PSMA8 -621.0
ANXA2 -686.0
SUMO1 -765.0
PRL -794.0
RNF7 -812.0
PSMD5 -828.0
PSMF1 -878.0
TOLLIP -904.0
BCL2L1 -922.0
GSDMD -963.0
NUP214 -1024.0
IL23R -1048.0
PIK3CA -1136.0
IL20RA -1138.0
MAP2K3 -1194.0
PSMB8 -1223.0
RIGI -1264.0
CFL1 -1276.0
NUP62 -1286.0
STAT5A -1288.0
RORA -1311.0
JAK3 -1325.0
IL22RA2 -1353.0
STAT1 -1367.0
IFNA13 -1395.0
SOD2 -1414.0
PITPNA -1433.0
H3C3 -1449.0
ATF1 -1525.0
RELA -1562.0
TRIM17 -1585.0
IL7R -1588.0
HNRNPF -1617.0
H3C12 -1618.0
PSMD4 -1623.0
IL22RA1 -1673.0
TRIM2 -1704.0
STXBP2 -1713.0
GHR -1776.0
PSMA5 -1800.0
CHUK -1813.0
IFNAR2 -1856.0
ISG15 -1906.0
IL9 -1926.0
ADAR -1934.0
TRIM35 -1954.0
MAPK7 -2007.0
KPNA5 -2085.0
RIPK2 -2148.0
NUP58 -2200.0
VRK3 -2210.0
TRIM68 -2211.0
ELOB -2229.0
CDKN1B -2241.0
PSMD9 -2254.0
CUL5 -2255.0
PPIA -2269.0
CXCL2 -2422.0
BTRC -2464.0
PSMB5 -2516.0
NUP98 -2594.0
TRIM62 -2612.0
TGFB1 -2633.0
MMP2 -2667.0
TIFA -2673.0
ARIH1 -2677.0
OAS1 -2701.0
NUP188 -2702.0
NUP205 -2719.0
EGR1 -2756.0
IL1RAP -2793.0
NUP210 -2808.0
H3C10 -2825.0
IL31RA -2836.0
MMP3 -2849.0
MAPKAPK2 -2865.0
IRS1 -2875.0
CASP3 -2880.0
GBP4 -2931.0
IL18RAP -2966.0
NUP153 -2967.0
IKBIP -2982.0
GBP6 -3059.0
ATF2 -3071.0
IL2RB -3110.0
DUSP4 -3134.0
PTPN5 -3155.0
TRIM26 -3170.0
PIK3CG -3174.0
TP53 -3217.0
PTPN11 -3223.0
PIK3R3 -3237.0
HLA-C -3246.0
FSCN1 -3309.0
CEBPD -3315.0
MAPK11 -3380.0
SOCS5 -3395.0
AGER -3463.0
TRIM34 -3490.0
CRLF1 -3505.0
UBE2D2 -3526.0
HLA-A -3534.0
IL5RA -3548.0
PRLR -3568.0
ITGB2 -3578.0
PPP2CB -3621.0
IL1A -3636.0
CD80 -3642.0
PPP2CA -3664.0
H3C11 -3750.0
N4BP1 -3816.0
BIRC5 -3821.0
PSMB9 -3852.0
IRF2 -3860.0
UBE2D1 -3873.0
NFKB1 -3915.0
PTPN23 -3990.0
KPNA1 -4042.0
YES1 -4047.0
TRIM6 -4072.0
CD70 -4193.0
DUSP7 -4215.0
IRF4 -4239.0
AAAS -4247.0
NLRX1 -4336.0
TRIM25 -4381.0
CCND1 -4388.0
PSMC2 -4425.0
PTGS2 -4452.0
SOCS6 -4464.0
TRIM3 -4466.0
NCAM1 -4575.0
TNIP2 -4587.0
HLA-DRB5 -4645.0
SDC1 -4653.0
SMARCA4 -4672.0
IRS2 -4673.0
XAF1 -4774.0
FYN -4809.0
HSP90AA1 -4827.0
POM121C -4889.0
STAT2 -4934.0
RPLP0 -4954.0
PLCG1 -4968.0
LIFR -4996.0
TAB2 -5041.0
TRIM46 -5052.0
USP18 -5104.0
NUP35 -5161.0
NOS2 -5167.0
IFNG -5195.0
IFNA2 -5215.0
MX1 -5270.0
IL12A -5279.0
PTPN4 -5314.0
VAMP2 -5341.0
VEGFA -5384.0
SOCS3 -5387.0
IRF3 -5401.0
PSMD1 -5434.0
IL36B -5437.0
CAMK2B -5445.0
AKT1 -5452.0
STX4 -5486.0
JUN -5493.0
EDARADD -5505.0
PLCG2 -5512.0
MX2 -5603.0
NFKBIA -5622.0
NUP107 -5699.0
TNFSF15 -5703.0
NDN -5704.0
TAB1 -5743.0
PPP2R5D -5799.0
RPS6KA5 -5871.0
VCAM1 -5924.0
PTPN14 -5938.0
FASLG -5977.0
PSME1 -5997.0
ALOX5 -6026.0
IL21 -6032.0
KPNA3 -6036.0
NUP50 -6058.0
EBI3 -6105.0
PSMB6 -6154.0
IFI6 -6291.0
RPS27A -6304.0
CISH -6376.0
HLA-F -6405.0
HLA-E -6426.0
GBP1 -6468.0
BLNK -6556.0
CA1 -6590.0
PTPN6 -6621.0
LAMA5 -6715.0
SNAP25 -6716.0
GBP7 -6768.0
MAP2K7 -6871.0
MEF2A -6877.0
H3C4 -6893.0
TNFRSF12A -6915.0
IL10RA -6917.0
PIK3CD -6920.0
IRF6 -7024.0
CSF1R -7089.0
CCL20 -7108.0
TNFRSF13B -7168.0
RELB -7198.0
ITGB1 -7226.0
ISG20 -7270.0
AKT2 -7272.0
IL37 -7277.0
MAPK3 -7281.0
IKBKB -7286.0
PSMD8 -7295.0
OPRD1 -7355.0
HRAS -7398.0
IFNA14 -7430.0
IL36A -7443.0
TNFRSF1B -7491.0
RPS6KA2 -7543.0
CD4 -7557.0
CNTF -7584.0
LBP -7587.0
S1PR1 -7596.0
COL1A2 -7661.0
PAK2 -7745.0
TNFSF9 -7754.0
TRIM5 -7820.0
IFIT3 -7874.0
TRIM10 -7908.0
TPR -7967.0
GATA3 -7998.0
NANOG -8002.0
HLA-DPB1 -8068.0
IL22 -8110.0
EIF4A3 -8186.0
CD36 -8219.0
GBP3 -8222.0
CSF3R -8231.0
RAG1 -8241.0
IL18BP -8250.0
TYK2 -8257.0
GBP2 -8291.0
TRAF2 -8333.0
TRIM22 -8406.0
INPPL1 -8423.0
FLNB -8446.0
TNFRSF18 -8519.0
IL13 -8573.0
FN1 -8702.0
BATF -8814.0
IL3 -8823.0
IFNA8 -8854.0
MAPK9 -8959.0
ALPK1 -9031.0
TRIM29 -9161.0
JAK2 -9201.0
IFNB1 -9255.0
SEC13 -9284.0
CCL11 -9311.0
TNFRSF25 -9446.0
RNASEL -9481.0
TNF -9561.0
IL17A -9620.0
LIF -9653.0
CSH1 -9725.0
IL25 -9768.0
MMP1 -9829.0
CAMK2A -9831.0
EDAR -9870.0
IL36RN -9965.0
IL1F10 -10002.0
IL17F -10083.0
PSMB11 -10167.0
FPR1 -10227.0
IL31 -10235.0
IFNA5 -10276.0
GH2 -10480.0
TNFRSF4 -10490.0
IFNA21 -10497.0
LTA -10550.0
GSTA2 -10585.0
TNFSF14 -10705.0
IL32 -10738.0
GH1 -10766.0


REACTOME_SIGNALING_BY_INTERLEUKINS

REACTOME_SIGNALING_BY_INTERLEUKINS
800
set REACTOME_SIGNALING_BY_INTERLEUKINS
setSize 444
pANOVA 0.00206
s.dist 0.0853
p.adjustANOVA 0.3



Top enriched genes

Top 20 genes
GeneID Gene Rank
IL27 11126
IFNL2 11102
PRTN3 11038
CTSG 11021
LGALS9 11011
CCL4 11009
CTF1 10969
CSF3 10953
CLCF1 10866
CCL22 10754
SERPINB2 10719
CCL3 10706
IL10 10644
IL1B 10591
IL17RE 10550
DUSP3 10526
TNFRSF1A 10393
POMC 10392
HGF 10328
SNRPA1 10246

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
IL27 11126.0
IFNL2 11102.0
PRTN3 11038.0
CTSG 11021.0
LGALS9 11011.0
CCL4 11009.0
CTF1 10969.0
CSF3 10953.0
CLCF1 10866.0
CCL22 10754.0
SERPINB2 10719.0
CCL3 10706.0
IL10 10644.0
IL1B 10591.0
IL17RE 10550.0
DUSP3 10526.0
TNFRSF1A 10393.0
POMC 10392.0
HGF 10328.0
SNRPA1 10246.0
LCN2 10211.0
GRB2 10092.0
NKIRAS2 10063.0
PSMA1 10043.0
CCL2 10003.0
IL6R 9975.0
NOD1 9966.0
PIK3R2 9942.0
P4HB 9931.0
ALOX15 9784.0
SAA1 9781.0
CANX 9768.0
RBX1 9765.0
UBE2N 9761.0
IL19 9686.0
RPS6KA1 9650.0
PSMA6 9587.0
H3C6 9586.0
PSMB10 9558.0
HSP90B1 9489.0
FCER2 9480.0
IRAK3 9452.0
SHC1 9449.0
IL17C 9440.0
IL1RN 9398.0
PELI3 9344.0
UBC 9309.0
IL26 9257.0
RHOU 9219.0
GSTO1 9004.0
CCR2 9002.0
PSMD13 8956.0
MAP2K1 8942.0
MAPK14 8871.0
IL2RA 8825.0
FGF2 8790.0
CCL19 8694.0
MMP9 8639.0
IL12RB1 8571.0
IFNLR1 8551.0
IL18 8424.0
MAP3K8 8362.0
ANXA1 8271.0
UBE2V1 8231.0
LCK 8208.0
SIGIRR 8194.0
PSMB7 8153.0
SOX2 8009.0
GAB2 7974.0
STX1A 7920.0
HIF1A 7846.0
CCR1 7845.0
MYD88 7749.0
CD86 7642.0
FOS 7498.0
YWHAZ 7406.0
S100B 7344.0
JAK1 7274.0
NKIRAS1 7269.0
IL11 7206.0
CSF2 7180.0
CRKL 7133.0
MTAP 7131.0
IL23A 7117.0
IL2 7028.0
TRAF6 7001.0
IFNL1 6955.0
STAT6 6912.0
MAP3K7 6877.0
CDKN1A 6874.0
ARF1 6868.0
POU2F1 6818.0
HCK 6804.0
FBXW11 6800.0
UBB 6789.0
PELI2 6745.0
CDC42 6585.0
CASP1 6508.0
IL34 6447.0
TEC 6441.0
IL6 6398.0
IL21R 6372.0
HAVCR2 6350.0
PSMB4 6341.0
TBK1 6319.0
TXLNA 6298.0
CASP8 6261.0
PRKACA 6257.0
RALA 6251.0
SMAD3 6244.0
SOD1 6156.0
IL1RL2 6148.0
LYN 6131.0
CUL1 6104.0
SOCS1 6069.0
LMNB1 6057.0
HMGB1 5972.0
STAT5B 5853.0
TSLP 5770.0
H3C8 5730.0
PSMD12 5712.0
CXCL1 5682.0
TWIST1 5681.0
PSMD3 5632.0
PSME3 5531.0
PSMB1 5505.0
PSMA3 5324.0
PSMC1 5255.0
VAV1 5248.0
MAP3K3 5203.0
PSMA2 5121.0
STAT3 5078.0
RORC 5048.0
IL27RA 5029.0
PTK2B 4956.0
PSMC3 4952.0
PTPN18 4947.0
PTPN2 4943.0
CNTFR 4891.0
IL16 4865.0
CXCL10 4844.0
SQSTM1 4813.0
NOD2 4792.0
INPP5D 4677.0
MUC1 4610.0
LCP1 4604.0
IL12B 4601.0
PELI1 4599.0
USP14 4516.0
H3C1 4493.0
IL20 4481.0
PSMC4 4459.0
PDCD4 4431.0
TCP1 4387.0
BCL2 4375.0
IL33 4203.0
IL7 4095.0
TALDO1 4022.0
PSMA7 3991.0
MAP2K6 3981.0
CSF1 3905.0
CSF2RB 3822.0
PIK3R1 3783.0
SOS1 3727.0
PSMD14 3675.0
IL20RB 3630.0
CCR5 3606.0
RAP1B 3595.0
PTPN12 3542.0
ICAM1 3541.0
ITGAM 3504.0
HSPA9 3464.0
SOS2 3404.0
IL4 3345.0
BCL6 3281.0
LRRC14 3274.0
FOXO3 3206.0
CAPZA1 3188.0
IL4R 3139.0
CCL5 3112.0
IL15 3108.0
OSM 3107.0
HSPA8 3085.0
PTPN7 3048.0
PPP2R1B 3019.0
IL12RB2 2984.0
IL11RA 2962.0
IRAK2 2933.0
IL1RL1 2909.0
CRK 2818.0
SOCS2 2793.0
RAPGEF1 2739.0
FOXO1 2702.0
IL36G 2673.0
CBL 2669.0
PSMC5 2665.0
IL24 2654.0
IL1R2 2653.0
STAT4 2641.0
IL10RB 2515.0
SYK 2502.0
MAPK10 2410.0
F13A1 2404.0
MIF 2231.0
OSMR 2107.0
RAG2 2015.0
UBA52 2012.0
NFKB2 1809.0
HNRNPA2B1 1788.0
H3C2 1718.0
PSME4 1702.0
APP 1659.0
PSME2 1571.0
HNRNPDL 1524.0
VIM 1515.0
MAP2K4 1464.0
S100A12 1431.0
NLRC5 1429.0
HMOX1 1310.0
DUSP6 1294.0
MAPK8 1248.0
ITGAX 1235.0
IL1R1 1205.0
PPP2R1A 1180.0
MEF2C 1109.0
OPRM1 1089.0
PIM1 1084.0
PTAFR 993.0
PTPN9 896.0
H3C7 814.5
BRWD1 805.0
AIP 800.0
PSMD7 646.0
PSMD6 620.0
PSMB3 544.0
IL6ST 500.0
IL17RB 421.0
JUNB 420.0
CREB1 418.0
IL17RC 362.0
STX3 335.0
SEM1 292.0
MYC 235.0
MCL1 185.0
ZEB1 165.0
IRAK4 129.0
IL17RA 119.0
PIK3CB 107.0
SKP1 51.0
PTPN13 -130.0
PTPRZ1 -190.0
CXCL8 -272.0
IL15RA -295.0
PSMC6 -296.0
MAPKAPK3 -304.0
CNN2 -330.0
MAPK1 -343.0
IL5 -367.0
PSMA4 -401.0
PSMD11 -439.0
PSMD2 -547.0
NFKBIB -565.0
IL18R1 -609.0
PSMB2 -611.0
PSMA8 -621.0
ANXA2 -686.0
PSMD5 -828.0
PSMF1 -878.0
TOLLIP -904.0
BCL2L1 -922.0
GSDMD -963.0
IL23R -1048.0
PIK3CA -1136.0
IL20RA -1138.0
MAP2K3 -1194.0
PSMB8 -1223.0
CFL1 -1276.0
STAT5A -1288.0
RORA -1311.0
JAK3 -1325.0
IL22RA2 -1353.0
STAT1 -1367.0
SOD2 -1414.0
PITPNA -1433.0
H3C3 -1449.0
ATF1 -1525.0
RELA -1562.0
IL7R -1588.0
HNRNPF -1617.0
H3C12 -1618.0
PSMD4 -1623.0
IL22RA1 -1673.0
STXBP2 -1713.0
PSMA5 -1800.0
CHUK -1813.0
IL9 -1926.0
MAPK7 -2007.0
RIPK2 -2148.0
VRK3 -2210.0
PSMD9 -2254.0
PPIA -2269.0
CXCL2 -2422.0
BTRC -2464.0
PSMB5 -2516.0
TGFB1 -2633.0
MMP2 -2667.0
TIFA -2673.0
IL1RAP -2793.0
H3C10 -2825.0
IL31RA -2836.0
MMP3 -2849.0
MAPKAPK2 -2865.0
IRS1 -2875.0
CASP3 -2880.0
IL18RAP -2966.0
IKBIP -2982.0
ATF2 -3071.0
IL2RB -3110.0
DUSP4 -3134.0
PTPN5 -3155.0
TP53 -3217.0
PTPN11 -3223.0
PIK3R3 -3237.0
FSCN1 -3309.0
CEBPD -3315.0
MAPK11 -3380.0
SOCS5 -3395.0
AGER -3463.0
CRLF1 -3505.0
IL5RA -3548.0
ITGB2 -3578.0
PPP2CB -3621.0
IL1A -3636.0
CD80 -3642.0
PPP2CA -3664.0
H3C11 -3750.0
N4BP1 -3816.0
BIRC5 -3821.0
PSMB9 -3852.0
NFKB1 -3915.0
PTPN23 -3990.0
YES1 -4047.0
DUSP7 -4215.0
IRF4 -4239.0
NLRX1 -4336.0
CCND1 -4388.0
PSMC2 -4425.0
PTGS2 -4452.0
TNIP2 -4587.0
SDC1 -4653.0
SMARCA4 -4672.0
IRS2 -4673.0
FYN -4809.0
HSP90AA1 -4827.0
STAT2 -4934.0
RPLP0 -4954.0
LIFR -4996.0
TAB2 -5041.0
USP18 -5104.0
NOS2 -5167.0
IFNG -5195.0
IL12A -5279.0
PTPN4 -5314.0
VAMP2 -5341.0
VEGFA -5384.0
SOCS3 -5387.0
PSMD1 -5434.0
IL36B -5437.0
AKT1 -5452.0
STX4 -5486.0
JUN -5493.0
NFKBIA -5622.0
NDN -5704.0
TAB1 -5743.0
PPP2R5D -5799.0
RPS6KA5 -5871.0
VCAM1 -5924.0
PTPN14 -5938.0
FASLG -5977.0
PSME1 -5997.0
ALOX5 -6026.0
IL21 -6032.0
EBI3 -6105.0
PSMB6 -6154.0
RPS27A -6304.0
CISH -6376.0
BLNK -6556.0
CA1 -6590.0
PTPN6 -6621.0
LAMA5 -6715.0
SNAP25 -6716.0
MAP2K7 -6871.0
MEF2A -6877.0
H3C4 -6893.0
IL10RA -6917.0
PIK3CD -6920.0
CSF1R -7089.0
CCL20 -7108.0
ITGB1 -7226.0
IL37 -7277.0
MAPK3 -7281.0
IKBKB -7286.0
PSMD8 -7295.0
OPRD1 -7355.0
IL36A -7443.0
TNFRSF1B -7491.0
RPS6KA2 -7543.0
CD4 -7557.0
CNTF -7584.0
LBP -7587.0
S1PR1 -7596.0
COL1A2 -7661.0
PAK2 -7745.0
GATA3 -7998.0
NANOG -8002.0
IL22 -8110.0
CD36 -8219.0
CSF3R -8231.0
RAG1 -8241.0
IL18BP -8250.0
TYK2 -8257.0
TRAF2 -8333.0
INPPL1 -8423.0
IL13 -8573.0
FN1 -8702.0
BATF -8814.0
IL3 -8823.0
MAPK9 -8959.0
ALPK1 -9031.0
JAK2 -9201.0
CCL11 -9311.0
TNF -9561.0
IL17A -9620.0
LIF -9653.0
IL25 -9768.0
MMP1 -9829.0
IL36RN -9965.0
IL1F10 -10002.0
IL17F -10083.0
PSMB11 -10167.0
FPR1 -10227.0
IL31 -10235.0
GSTA2 -10585.0
IL32 -10738.0


REACTOME_ACYL_CHAIN_REMODELLING_OF_PC

REACTOME_ACYL_CHAIN_REMODELLING_OF_PC
119
set REACTOME_ACYL_CHAIN_REMODELLING_OF_PC
setSize 27
pANOVA 0.00225
s.dist -0.34
p.adjustANOVA 0.3



Top enriched genes

Top 20 genes
GeneID Gene Rank
PLA2G2D -10500
PLA2G2E -10384
PLA2G10 -10327
TMEM86B -9801
PLA2G2F -9001
PLA2G12A -8876
PLA2G4B -8652
PLA2G4E -8019
PLA2G6 -6800
PLA2G2A -6567
PLB1 -6123
PLA2G4F -5201
LPCAT2 -4016
PLA2R1 -3833
PLA2G3 -3541
PLA2G4A -2863
PLAAT3 -2480
LPCAT1 -2389
LPCAT3 -1205
PLA2G4D -1116

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PLA2G2D -10500
PLA2G2E -10384
PLA2G10 -10327
TMEM86B -9801
PLA2G2F -9001
PLA2G12A -8876
PLA2G4B -8652
PLA2G4E -8019
PLA2G6 -6800
PLA2G2A -6567
PLB1 -6123
PLA2G4F -5201
LPCAT2 -4016
PLA2R1 -3833
PLA2G3 -3541
PLA2G4A -2863
PLAAT3 -2480
LPCAT1 -2389
LPCAT3 -1205
PLA2G4D -1116
PNPLA8 -302
PLA2G5 -252
MBOAT2 2644
PLBD1 3805
LPCAT4 4317
PLA2G4C 5550
PLA2G1B 9556


REACTOME_CELLULAR_RESPONSE_TO_CHEMICAL_STRESS

REACTOME_CELLULAR_RESPONSE_TO_CHEMICAL_STRESS
1583
set REACTOME_CELLULAR_RESPONSE_TO_CHEMICAL_STRESS
setSize 188
pANOVA 0.00231
s.dist 0.129
p.adjustANOVA 0.3



Top enriched genes

Top 20 genes
GeneID Gene Rank
MAFG 10830
GSTP1 10237
PSMA1 10043
ATF4 10029
P4HB 9931
NCF2 9776
RBX1 9765
NLRP3 9638
PSMA6 9587
PSMB10 9558
PRKCD 9555
CSNK2A1 9436
SOD3 9313
UBC 9309
RXRA 9014
COX6A1 8978
HBA1 8972
PSMD13 8956
GPX3 8882
GPX7 8864

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MAFG 10830
GSTP1 10237
PSMA1 10043
ATF4 10029
P4HB 9931
NCF2 9776
RBX1 9765
NLRP3 9638
PSMA6 9587
PSMB10 9558
PRKCD 9555
CSNK2A1 9436
SOD3 9313
UBC 9309
RXRA 9014
COX6A1 8978
HBA1 8972
PSMD13 8956
GPX3 8882
GPX7 8864
GPX1 8853
BACH1 8787
TRIM21 8622
PTK6 8335
CHD9 8289
HBA2 8285
BLVRB 8230
PSMB7 8153
TXN 8058
SCO2 7917
SESN2 7821
COX5A 7752
BRCA1 7745
COX7C 7723
BLVRA 7345
CDKN2A 7234
CDKN1A 6874
UBB 6789
NPLOC4 6645
UBXN7 6612
PGD 6610
PSMB4 6341
SOD1 6156
GPX2 6120
TXNRD1 6118
CUL1 6104
SKP2 6091
GSTA1 6060
GSK3B 5966
PSMD12 5712
CAT 5678
IDH1 5637
PSMD3 5632
PSME3 5531
PSMB1 5505
PSMA3 5324
PSMC1 5255
PSMA2 5121
STAT3 5078
PSMC3 4952
SQSTM1 4813
PSMC4 4459
HM13 4410
NUDT2 4324
COX4I1 4271
TGS1 4141
TACO1 4122
COX8A 4100
NCOA2 4037
TALDO1 4022
PSMA7 3991
GPX8 3680
PSMD14 3675
CUL3 3602
COX16 3575
COX18 3478
PALB2 3433
CSNK2B 3095
PRDX6 2907
PRDX2 2680
PSMC5 2665
COX19 2299
LRPPRC 2184
NCOR1 2083
UBA52 2012
NFE2L2 1942
GCLC 1903
ATOX1 1811
ABCC1 1800
PSME4 1702
MAP1LC3B 1668
NCOA6 1636
PSME2 1571
COX6B1 1526
GSTA3 1518
SESN1 1418
HMOX1 1310
AKT3 1256
COX6C 721
COX11 710
PSMD7 646
PSMD6 620
NCF4 569
PSMB3 544
AQP8 409
TXN2 377
SEM1 292
MYC 235
DPP3 216
NOX4 123
SKP1 51
GPX6 -108
SIN3A -157
PSMC6 -296
GCLM -359
PSMA4 -401
KEAP1 -423
PSMD11 -439
GSR -469
PSMD2 -547
COX14 -553
PSMB2 -611
PSMA8 -621
CSNK2A2 -630
PSMD5 -828
PSMF1 -878
SLC7A11 -949
PRDX1 -1220
PSMB8 -1223
TBL1XR1 -1303
NCOR2 -1309
FBXL17 -1351
SOD2 -1414
TKT -1527
PSMD4 -1623
ME1 -1670
STAP2 -1709
MED1 -1730
PSMA5 -1800
NOTCH1 -1962
NDUFA4 -2120
PSMD9 -2254
MUL1 -2387
BTRC -2464
CREBBP -2481
HELZ2 -2484
PSMB5 -2516
TXNRD2 -2585
PRDX5 -2641
HDAC3 -2760
MAFK -3078
ERO1A -3094
GPX5 -3689
CYCS -3692
PPARA -3818
PSMB9 -3852
HMOX2 -3881
COX20 -3971
SMARCD3 -4285
PSMC2 -4425
CARM1 -4597
NOX5 -4699
PRDX3 -5174
NQO1 -5433
PSMD1 -5434
AKT1 -5452
TXNIP -5484
PSME1 -5997
PSMB6 -6154
RPS27A -6304
NCOA1 -6320
EP300 -6335
COX5B -6340
ALB -6375
HBB -6457
VCP -6635
UFD1 -6651
SRXN1 -6655
CYBA -6835
AKT2 -7272
PSMD8 -7295
COX7A2L -8264
SCO1 -8311
CCS -8611
FABP1 -8995
SURF1 -9100
SIN3B -9365
PSMB11 -10167


REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX
115
set REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX
setSize 134
pANOVA 0.00233
s.dist -0.152
p.adjustANOVA 0.3



Top enriched genes

Top 20 genes
GeneID Gene Rank
KLKB1 -10568
PRSS1 -10536
CTRB2 -10525
CTRB1 -10356
BMP1 -10241
MMP8 -10228
COL13A1 -9833
MMP1 -9829
HSPG2 -9741
FBN3 -9468
CAPN14 -9370
OPTC -9160
COL5A1 -9077
CAPN10 -9038
CAPN5 -8979
CAPN13 -8933
FN1 -8702
MMP15 -8683
COL6A3 -8576
COL10A1 -8545

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
KLKB1 -10568
PRSS1 -10536
CTRB2 -10525
CTRB1 -10356
BMP1 -10241
MMP8 -10228
COL13A1 -9833
MMP1 -9829
HSPG2 -9741
FBN3 -9468
CAPN14 -9370
OPTC -9160
COL5A1 -9077
CAPN10 -9038
CAPN5 -8979
CAPN13 -8933
FN1 -8702
MMP15 -8683
COL6A3 -8576
COL10A1 -8545
COL6A2 -8485
CAPN3 -8292
MMP17 -8276
SCUBE1 -8106
COL4A2 -8097
CAPNS2 -7847
COL1A2 -7661
COL11A2 -7521
COL6A1 -7455
LAMB3 -7341
COL8A2 -6928
ACAN -6904
ADAM9 -6889
LAMA5 -6715
FURIN -6560
CMA1 -6402
COL18A1 -6292
CAPN9 -5725
COL4A1 -5280
LAMC1 -5276
NCSTN -5119
ADAMTS16 -5047
DCN -5025
FBN1 -4995
CAPN8 -4671
PHYKPL -4660
COL26A1 -4630
HTRA1 -4324
COL17A1 -4260
FBN2 -4213
CAPN15 -4032
BSG -3954
ADAM15 -3944
LAMC2 -3737
A2M -3721
MMP12 -3457
KLK2 -3146
CAST -2994
SCUBE3 -2977
MMP7 -2969
CASP3 -2880
MMP3 -2849
COL16A1 -2805
COL2A1 -2800
MMP2 -2667
COL7A1 -2472
COL3A1 -2263
CAPN11 -2252
CAPN2 -2117
TMPRSS6 -1844
MMP25 -780
MMP24 -724
CAPN7 -716
MMP10 -569
COL1A1 -337
COL14A1 -270
ADAM17 -76
CDH1 279
CAPNS1 346
LAMB1 548
COL19A1 564
COL23A1 782
COL4A4 826
CTSL 886
CTSS 1093
ADAM8 1152
COL8A1 1239
COL9A2 1244
MMP20 1683
TLL2 1736
MMP11 1757
COL4A3 1789
CD44 1970
CTSB 2023
CAPN1 2045
ADAMTS8 2163
MMP13 2198
COL5A2 2274
LAMA3 2328
COL6A5 2361
NID1 2763
ADAMTS18 2801
MMP14 2893
ADAMTS1 2922
ADAMTS9 2931
SPOCK3 3028
TLL1 3083
COL9A1 3419
TIMP2 3529
ADAM10 3627
ADAMTS5 3878
COL11A1 4075
PSEN1 4160
SPP1 4654
CAPN12 5119
COL15A1 5146
ADAMTS4 5667
ELN 6199
COL12A1 6255
COL25A1 6365
COL6A6 6433
COL5A3 6596
MMP16 6806
PLG 7350
MMP9 8639
MMP19 8726
KLK7 8874
CTSK 9728
CTSV 9903
BCAN 9933
COL9A3 10111
CTSD 10690
ELANE 10883
CTSG 11021


REACTOME_PROGRAMMED_CELL_DEATH

REACTOME_PROGRAMMED_CELL_DEATH
865
set REACTOME_PROGRAMMED_CELL_DEATH
setSize 204
pANOVA 0.0027
s.dist 0.122
p.adjustANOVA 0.3



Top enriched genes

Top 20 genes
GeneID Gene Rank
SFN 11067
ELANE 10883
GSN 10627
IL1B 10591
CASP5 10048
TNFRSF10B 10045
PSMA1 10043
CD14 9901
APIP 9758
UBE2L3 9744
ACIN1 9702
PSMA6 9587
PSMB10 9558
PRKCD 9555
CHMP4C 9505
UBC 9309
YWHAG 9119
DFFA 9078
PSMD13 8956
UACA 8912

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SFN 11067
ELANE 10883
GSN 10627
IL1B 10591
CASP5 10048
TNFRSF10B 10045
PSMA1 10043
CD14 9901
APIP 9758
UBE2L3 9744
ACIN1 9702
PSMA6 9587
PSMB10 9558
PRKCD 9555
CHMP4C 9505
UBC 9309
YWHAG 9119
DFFA 9078
PSMD13 8956
UACA 8912
DBNL 8749
TRADD 8562
OCLN 8553
ADD1 8465
IL18 8424
CARD8 8410
H1-3 8345
CASP6 8201
PSMB7 8153
RIPK3 8050
DSG2 7765
SDCBP 7725
TLR4 7476
YWHAZ 7406
BMF 7370
DAPK2 7312
PPP3R1 7266
CDKN2A 7234
BBC3 7198
DSG1 7175
H1-4 7174
UBB 6789
TP53BP2 6552
CASP1 6508
CASP7 6472
PSMB4 6341
DSG3 6312
CASP8 6261
APPL1 6224
SATB1 6212
LMNB1 6057
HMGB1 5972
PSMD12 5712
PSMD3 5632
LMNA 5585
FLOT1 5576
PSME3 5531
PSMB1 5505
PSMA3 5324
TICAM2 5257
PSMC1 5255
BIRC3 5187
PSMA2 5121
STAT3 5078
PSMC3 4952
DIABLO 4929
FADD 4876
PELI1 4599
BCL2L11 4581
BAD 4509
PSMC4 4459
BCL2 4375
OMA1 4346
DCC 4163
H1-1 4131
HMGB2 4061
DYNLL1 4014
PSMA7 3991
KPNB1 3909
PSMD14 3675
IRF1 3625
H1-2 3500
CHMP4B 3367
DFFB 3148
ARHGAP10 3124
TFDP2 3041
PTK2 2838
PDCD6IP 2715
TICAM1 2667
PSMC5 2665
PMAIP1 2645
CFLAR 2213
CHMP3 2174
STUB1 2116
UBA52 2012
TNFSF10 1915
H1-0 1896
TNFRSF10A 1837
PSME4 1702
DNM1L 1630
PSME2 1571
VIM 1515
AKT3 1256
MAPK8 1248
PPP3CC 1186
ITCH 944
ROCK1 906
YWHAB 890
BAK1 667
PSMD7 646
PSMD6 620
PSMB3 544
SEM1 292
CDH1 279
BIRC2 154
TP73 82
YWHAE -5
PSMC6 -296
MAPK1 -343
PSMA4 -401
OPA1 -415
PSMD11 -439
DYNLL2 -462
PSMD2 -547
YWHAH -558
PSMB2 -611
PSMA8 -621
TP63 -648
AVEN -656
PSMD5 -828
PRKN -849
CHMP2B -859
PSMF1 -878
PPP1R13B -913
BCL2L1 -922
GSDMD -963
UNC5B -1033
PSMB8 -1223
CHMP2A -1412
MAPT -1418
APC -1581
PSMD4 -1623
BID -1669
PSMA5 -1800
CTNNB1 -1892
MLKL -2046
PSMD9 -2254
E2F1 -2318
PRKCQ -2320
GSDME -2390
UNC5A -2399
YWHAQ -2486
PSMB5 -2516
APAF1 -2526
FNTA -2544
TJP2 -2573
NMT1 -2584
SEPTIN4 -2637
PLEC -2834
CASP3 -2880
LY96 -3154
TP53 -3217
CDC37 -3241
CLSPN -3446
IL1A -3636
CYCS -3692
FAS -3797
PSMB9 -3852
IRF2 -3860
GAS2 -3870
KPNA1 -4042
CHMP6 -4077
CASP9 -4145
PSMC2 -4425
GZMB -4445
HSP90AA1 -4827
TFDP1 -4875
TJP1 -5048
DSP -5072
CHMP7 -5403
PSMD1 -5434
AKT1 -5452
FASLG -5977
PSME1 -5997
PSMB6 -6154
RPS27A -6304
PKP1 -6481
FLOT2 -6500
H1-5 -6844
CHMP4A -6864
AKT2 -7272
MAPK3 -7281
PSMD8 -7295
DAPK1 -7413
BAX -7528
PAK2 -7745
SPTAN1 -7825
STK24 -7984
TRAF2 -8333
DAPK3 -8881
CASP4 -9205
C1QBP -9678
PSMB11 -10167
RIPK1 -10392


REACTOME_ATF6_ATF6_ALPHA_ACTIVATES_CHAPERONES

REACTOME_ATF6_ATF6_ALPHA_ACTIVATES_CHAPERONES
620
set REACTOME_ATF6_ATF6_ALPHA_ACTIVATES_CHAPERONES
setSize 11
pANOVA 0.00287
s.dist 0.519
p.adjustANOVA 0.3



Top enriched genes

Top 20 genes
GeneID Gene Rank
DDIT3 10329
ATF4 10029
CALR 9928
HSP90B1 9489
XBP1 9400
HSPA5 8402
NFYB 4893
MBTPS1 3845
ATF6 75
NFYC -782
NFYA -1006

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DDIT3 10329
ATF4 10029
CALR 9928
HSP90B1 9489
XBP1 9400
HSPA5 8402
NFYB 4893
MBTPS1 3845
ATF6 75
NFYC -782
NFYA -1006


REACTOME_METABOLISM_OF_RNA

REACTOME_METABOLISM_OF_RNA
1313
set REACTOME_METABOLISM_OF_RNA
setSize 675
pANOVA 0.00295
s.dist 0.0671
p.adjustANOVA 0.3



Top enriched genes

Top 20 genes
GeneID Gene Rank
TNFSF13 11053
APOBEC3A 10889
SF3B6 10822
NXF1 10681
SRSF12 10495
PAIP1 10409
EIF4G1 10349
POLR2J 10348
TRA2B 10344
SNRPA1 10246
RPL37 10222
ANP32A 10190
PSMA1 10043
C2orf49 9978
RRP36 9820
GLE1 9720
RPL23 9710
ACIN1 9702
APOBEC1 9696
RPL35A 9690

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TNFSF13 11053.0
APOBEC3A 10889.0
SF3B6 10822.0
NXF1 10681.0
SRSF12 10495.0
PAIP1 10409.0
EIF4G1 10349.0
POLR2J 10348.0
TRA2B 10344.0
SNRPA1 10246.0
RPL37 10222.0
ANP32A 10190.0
PSMA1 10043.0
C2orf49 9978.0
RRP36 9820.0
GLE1 9720.0
RPL23 9710.0
ACIN1 9702.0
APOBEC1 9696.0
RPL35A 9690.0
TYW1 9678.0
KRR1 9671.0
PSMA6 9587.0
PSMB10 9558.0
DCAF13 9557.0
PRKCD 9555.0
ZMAT5 9543.0
CCDC12 9539.0
WBP11 9533.0
CSNK1E 9522.0
HNRNPA3 9482.0
PRORP 9472.0
SNUPN 9455.0
RPS28 9388.0
GTF2H4 9368.0
UBC 9309.0
RIOK2 9296.0
SYMPK 9272.0
DCPS 9268.0
METTL1 9232.0
NUP155 9225.0
MAGOH 9167.0
DDX5 9122.0
NSRP1 9111.0
ZMAT2 9097.0
SKIC8 8980.0
TRMT6 8979.0
PSMD13 8956.0
TP53RK 8879.0
MAPK14 8871.0
UTP25 8870.0
RBM22 8754.0
SNRPB2 8696.0
THOC5 8695.0
ZNF830 8598.0
APOBEC3B 8505.0
TRMT5 8412.0
POM121 8341.0
DDX39B 8252.0
HNRNPU 8181.0
PSMB7 8153.0
RPS29 8130.0
SRSF8 8090.0
SKIC3 8081.0
POLR2K 8079.0
SF3B1 8065.0
IK 8043.0
LSM10 7985.0
CCNH 7926.0
POLR2G 7915.0
RBM7 7911.0
RPS27L 7878.0
NUP85 7856.0
MFAP1 7812.0
RPL14 7799.0
TRMT10A 7795.0
HSPA1A 7743.0
RPL37A 7721.0
EDC3 7695.0
GTF2H3 7687.0
ZC3H11A 7657.0
ADARB1 7639.0
GEMIN6 7536.0
CNOT6L 7441.0
RPL15 7418.0
YWHAZ 7406.0
RPS25 7391.0
PPIL4 7384.0
USP39 7341.0
PRKRIP1 7313.0
NUP93 7294.0
THOC6 7214.0
SLU7 7178.0
ETF1 7147.0
UTP6 7130.0
THG1L 7085.0
SNRNP35 6985.0
RPL22L1 6979.0
SMG6 6965.0
SET 6951.0
DIS3 6935.0
GEMIN5 6916.0
RIOK3 6904.0
HNRNPA1 6887.0
RPL41 6881.0
SARNP 6876.0
U2SURP 6850.0
RPL38 6795.0
NOL12 6794.0
UBB 6789.0
NUP43 6787.0
PAN3 6771.0
SNRPF 6766.0
DDX20 6760.0
DHX8 6752.0
RPL5 6723.0
RBM8A 6706.0
RPP38 6693.0
HNRNPD 6565.0
PCBP2 6525.0
SMN1 6510.5
SMN2 6510.5
CPSF3 6505.0
GSPT1 6461.0
RPL17 6445.0
RAN 6431.0
NCL 6421.0
C9orf78 6414.0
GTF2H1 6356.0
PSMB4 6341.0
LSM1 6327.0
RPS8 6323.0
WDR36 6317.0
DCP1B 6295.0
PHF5A 6284.0
SF3B3 6254.0
TUT4 6203.0
RIOK1 6192.0
NOP14 6190.0
FAM32A 6126.0
ERI1 6094.0
NOP10 6055.0
RPL32 6049.0
POP5 6002.0
SEH1L 6001.0
NUP88 5943.0
NUDT21 5931.0
HSPB1 5926.0
NAT10 5925.0
DDX21 5902.0
YBX1 5890.0
RPS9 5759.0
UPF2 5746.0
PUS3 5736.0
PSMD12 5712.0
CNOT8 5687.0
SENP3 5663.0
PRPF18 5634.0
PSMD3 5632.0
PPP2R2A 5613.0
BUD31 5586.0
DCP2 5583.0
RPL34 5563.0
ADAT1 5549.0
WDR77 5540.0
NXT1 5535.0
PSME3 5531.0
NUP133 5513.0
HBS1L 5507.0
FTSJ3 5506.0
PSMB1 5505.0
TPRKB 5477.0
RBM39 5457.0
SRSF7 5362.0
PSMA3 5324.0
PSMC1 5255.0
DIMT1 5240.0
SLBP 5223.0
NUP42 5142.0
PSMA2 5121.0
DHX15 5114.0
TNPO1 5107.0
CPSF6 5101.0
CDC5L 5021.0
EXOSC7 4999.0
SNRNP27 4985.0
RPL31 4979.0
PSMC3 4952.0
SMU1 4916.0
ADAT3 4821.0
RPS16 4781.0
UTP4 4713.0
WDR3 4708.0
MPHOSPH6 4666.0
MTO1 4653.0
RPS24 4646.0
OSGEP 4628.0
TSEN34 4622.0
PCBP1 4615.0
NOP2 4600.0
PELP1 4594.0
CTU1 4582.0
PCF11 4555.0
POLR2C 4490.0
THADA 4486.0
PSMC4 4459.0
ZBTB8OS 4374.0
CLP1 4372.0
PRPF6 4357.0
PAPOLA 4282.0
ISG20L2 4250.0
RANBP2 4242.0
PNN 4195.0
WDR75 4192.0
CNOT10 4171.0
MRM2 4158.0
TGS1 4141.0
PWP2 4133.0
DHX16 4038.0
DUS2 4031.0
PPWD1 4027.0
PSMA7 3991.0
NIP7 3980.0
RPL28 3944.0
EXOSC9 3893.0
SRRT 3859.0
RPL13 3854.0
CWC25 3848.0
GEMIN4 3746.0
WDR43 3733.0
SMG9 3730.0
PSMD14 3675.0
EBNA1BP2 3657.0
SRSF10 3656.0
LSM6 3564.0
RPL11 3513.0
IGF2BP3 3492.0
LSM4 3491.0
PPIG 3482.0
POLR2D 3460.0
TRDMT1 3452.0
RPL24 3384.0
DHX9 3346.0
METTL14 3336.0
EIF4E 3335.0
RPS27 3238.0
SNRPD3 3225.0
PNRC2 3199.0
UPF1 3170.0
POLR2H 3166.0
SRSF4 3087.0
HSPA8 3085.0
RPS15A 3050.0
DDX39A 2971.0
SNRPD2 2963.0
UTP3 2927.0
POLR2L 2911.0
RPS19 2895.0
FYTTD1 2888.0
IGF2BP2 2879.0
PRPF38A 2869.0
DDX23 2788.0
MTREX 2771.0
GNL3 2767.0
RBM42 2765.0
FAU 2743.0
RPL36AL 2699.5
SF1 2674.0
PSMC5 2665.0
RPL12 2663.0
LENG1 2628.0
EFTUD2 2570.0
EIF4B 2566.0
ISY1 2561.0
CNOT4 2541.0
SF3B2 2535.0
POLR2F 2465.0
PDCD11 2271.0
IMP3 2256.0
RPS12 2251.0
UTP15 2183.0
LSM11 2180.0
SNU13 2140.0
TRMT9B 2061.0
UBA52 2012.0
ALKBH8 1967.0
EIF4A1 1962.0
HNRNPC 1935.0
XRN2 1932.0
WDR46 1899.0
CPSF2 1865.0
NOP58 1797.0
HNRNPA2B1 1788.0
KHSRP 1779.0
RPL27 1763.0
RPS20 1739.0
PSME4 1702.0
SMG7 1696.0
NCBP1 1650.0
ERCC3 1635.0
RPS13 1623.0
HNRNPM 1619.0
TCERG1 1610.0
PSME2 1571.0
CWC22 1499.0
RRP9 1453.0
WTAP 1410.0
BYSL 1398.0
GTF2F2 1394.0
RRP7A 1392.0
SNRPA 1381.0
CDC40 1379.0
TRMT11 1357.0
NUP54 1296.0
RAE1 1241.0
DDX52 1220.0
PPP2R1A 1180.0
DDX6 1167.0
TRMT61B 1155.0
RPL7 1149.0
RPL9 1142.0
RPS26 1136.0
RPLP1 1131.0
DDX47 1130.0
RPS5 1110.0
RPS3A 1022.0
TRMT13 1014.0
RPL36 1009.0
EXOSC10 1008.0
UTP20 969.0
RPL3L 937.0
SNRNP70 919.0
CLNS1A 910.0
RPS11 901.0
YWHAB 890.0
HNRNPL 879.0
PPIL3 831.0
RPL22 828.0
CNOT7 781.0
PES1 779.0
RPS21 768.0
GTF2H5 738.0
THUMPD1 727.0
PARN 674.0
WDR33 651.0
PSMD7 646.0
CWF19L2 641.0
WDR70 637.0
PSMD6 620.0
CASC3 616.0
NDC1 596.0
EXOSC4 586.0
SMG8 565.0
PSMB3 544.0
POLDIP3 532.0
SRSF11 531.0
DNAJC8 530.0
NSUN4 462.0
THOC7 419.0
ZNF473 385.0
MRM3 367.0
CSTF1 296.0
SEM1 292.0
PRMT5 288.0
ZCRB1 211.0
CWC15 127.0
SMG5 125.0
PRPF4 94.0
RPL21 81.0
NHP2 57.0
MRM1 -32.0
XRN1 -98.0
NUP37 -104.0
RPL18 -134.0
PATL1 -160.0
RPL19 -184.0
NUP160 -214.0
SNRPC -215.0
EXOSC5 -224.0
DDX49 -225.0
EIF4A2 -247.0
HNRNPR -268.0
U2AF1L4 -292.0
PSMC6 -296.0
DDX42 -344.0
FAM98B -375.0
CHTOP -382.0
PSMA4 -401.0
PSMD11 -439.0
RBM28 -472.0
HEATR1 -504.0
FUS -516.0
PSMD2 -547.0
TRMT12 -573.0
PSMB2 -611.0
PSMA8 -621.0
SYF2 -631.0
ZFP36L1 -635.0
PNO1 -636.0
PTBP1 -663.0
RPS18 -732.0
POLR2I -759.0
PLRG1 -761.0
CSTF3 -777.0
SRSF3 -813.0
SART1 -824.0
APOBEC4 -825.0
PSMD5 -828.0
IGF2BP1 -871.0
GCFC2 -875.0
PSMF1 -878.0
EPRS1 -909.0
TRNT1 -938.0
RPP25 -980.0
METTL3 -992.0
CNOT2 -993.0
PRKCA -1005.0
NUP214 -1024.0
C1D -1044.0
RNPC3 -1098.0
UTP11 -1099.0
WDR12 -1105.0
SNIP1 -1198.0
RPS10 -1200.0
BUD23 -1212.0
PSMB8 -1223.0
CNOT11 -1226.0
TSEN15 -1229.0
NUP62 -1286.0
DHX38 -1294.0
MNAT1 -1296.0
DCP1A -1405.0
SDE2 -1430.0
LSM5 -1463.0
SF3A3 -1472.0
GEMIN7 -1514.0
HNRNPH1 -1530.0
CPSF7 -1578.0
SRRM1 -1601.0
HNRNPF -1617.0
ADAT2 -1621.0
PSMD4 -1623.0
PUF60 -1638.0
RCL1 -1656.0
APOBEC3C -1683.0
RPL10A -1739.0
TNKS1BP1 -1767.0
PRCC -1768.0
PSMA5 -1800.0
RNMT -1836.0
APOBEC2 -1873.0
FCF1 -1889.0
RBM17 -1909.0
SNRPG -1929.0
POLR2E -1933.0
ADAR -1934.0
XPO1 -1967.0
SRSF1 -1977.0
GAR1 -1998.0
BOP1 -2011.0
RPL35 -2041.0
RPP21 -2144.0
CWC27 -2160.0
CDK7 -2169.0
NUP58 -2200.0
POLR2B -2223.0
RPL6 -2236.0
PSMD9 -2254.0
NCBP2 -2301.0
TFB1M -2311.0
FIP1L1 -2317.0
NT5C3B -2323.0
RPS7 -2349.0
ELAVL1 -2358.0
TSR3 -2373.0
RPS6 -2392.0
PRPF8 -2393.0
LUC7L3 -2415.0
TUT7 -2432.0
RNGTT -2446.0
PDCD7 -2457.0
MPHOSPH10 -2474.0
EXOSC3 -2512.0
PSMB5 -2516.0
NUP98 -2594.0
SAP18 -2595.0
SF3B5 -2600.0
TRMT10C -2608.0
TXNL4A -2638.0
PRPF3 -2654.0
POP7 -2698.0
NUP188 -2702.0
NUP205 -2719.0
TRMT1 -2723.0
PAN2 -2729.0
RPL26 -2773.0
NUP210 -2808.0
CSNK1D -2823.0
MAPKAPK2 -2865.0
RPPH1 -2871.0
RBM25 -2900.0
LSM2 -2926.0
CDKAL1 -2933.0
NUP153 -2967.0
SF3A1 -3006.0
UPF3A -3016.0
EMG1 -3040.0
UTP18 -3074.0
LSM3 -3082.0
RPL27A -3107.0
RTRAF -3148.0
CTNNBL1 -3211.0
SNRPN -3213.0
PUS1 -3299.0
SRSF2 -3316.0
MAPK11 -3380.0
CSTF2T -3402.0
CACTIN -3414.0
SNRPE -3433.0
PRPF19 -3437.0
SNRNP25 -3441.0
UBL5 -3456.0
HNRNPK -3567.0
PABPN1 -3580.0
RPL4 -3582.0
LSM8 -3609.0
RPL23A -3634.0
RBM5 -3641.0
PPP2CA -3664.0
CNOT6 -3696.0
RPL8 -3745.0
ALYREF -3838.0
PSMB9 -3852.0
CRNKL1 -3869.0
SNW1 -3879.0
NOL11 -4057.0
PRPF31 -4066.0
POLR2A -4110.0
AAAS -4247.0
PPIH -4371.0
GTF2F1 -4385.0
PSMC2 -4425.0
MAGOHB -4449.0
RPL26L1 -4465.0
LCMT2 -4508.0
TRMT44 -4614.0
RRP1 -4644.0
PPIL1 -4689.0
TSEN2 -4693.0
DHX35 -4770.0
WBP4 -4857.0
RPL3 -4879.0
POM121C -4889.0
RPLP0 -4954.0
TRMT61A -4987.0
WDR18 -4993.0
RPSA -4998.0
QTRT1 -5050.0
TRMT112 -5062.0
EXOSC8 -5087.0
DDX41 -5116.0
NUP35 -5161.0
XAB2 -5163.0
TRIT1 -5211.0
EXOSC6 -5221.0
RPS14 -5236.0
SUPT5H -5253.0
IMP4 -5259.0
RPP14 -5272.0
CTU2 -5289.0
EXOSC2 -5329.0
RPL39L -5346.0
SNRNP40 -5353.0
PHAX -5368.0
PSMD1 -5434.0
AKT1 -5452.0
SRSF6 -5468.0
NSUN6 -5476.0
SNRPD1 -5479.0
QTRT2 -5528.0
SRSF5 -5611.0
SF3B4 -5629.0
GPATCH1 -5639.0
URM1 -5661.0
DDX1 -5687.0
NUP107 -5699.0
RPS15 -5723.0
TSEN54 -5735.0
RPS3 -5759.0
PUS7 -5776.0
TSR1 -5800.0
RPLP2 -5885.0
TYW5 -5907.0
SMNDC1 -5915.0
SKIC2 -5928.0
PSME1 -5997.0
NUP50 -6058.0
TFIP11 -6141.0
RTCB -6144.0
PSMB6 -6154.0
NOL6 -6191.0
CNOT9 -6197.0
RPL18A -6198.0
BUD13 -6226.0
ERCC2 -6258.0
U2AF2 -6277.0
RPP30 -6294.0
POP1 -6296.0
RPS27A -6304.0
ELAC2 -6460.0
CPSF4 -6489.0
TEX10 -6499.0
NOL9 -6648.0
PRPF40A -6650.0
NSUN2 -6666.0
RPL30 -6692.0
MTERF4 -6702.0
A1CF -6812.0
LSM7 -6924.0
EXOSC1 -6949.0
YJU2 -6953.0
NOB1 -7054.0
AQR -7119.0
GTPBP3 -7166.0
FBL -7169.0
NOC4L -7207.0
PSMD8 -7295.0
THOC1 -7348.0
SRSF9 -7483.0
SNRPB -7555.0
PABPC1 -7558.0
DHX37 -7565.0
RPL29 -7577.0
DDX46 -7581.0
SUGP1 -7599.0
RPS23 -7689.0
BCAS2 -7702.0
ZFP36 -7714.0
RPL7A -7724.0
WDR4 -7853.0
BMS1 -7955.0
TPR -7967.0
CCAR1 -8076.0
EDC4 -8117.0
EIF4A3 -8186.0
RNPS1 -8192.0
SF3A2 -8209.0
CNOT1 -8267.0
TYW3 -8274.0
LTV1 -8386.0
CPSF1 -8455.0
PPIE -8536.0
RPP40 -8587.0
SMG1 -8606.0
UTP14C -8668.0
SNRNP200 -8782.0
TRMU -8820.0
RPL13A -8873.5
PPIL2 -8878.0
SNRNP48 -8935.0
PPP1R8 -8953.0
RPL10L -8965.0
CNOT3 -9069.0
TBL3 -9108.0
RPS2 -9117.0
CHERP -9120.0
XPOT -9127.0
APOBEC3H -9145.0
SRRM2 -9233.0
SEC13 -9284.0
NOP56 -9359.0
POP4 -9729.0
GEMIN2 -9859.0
PSMB11 -10167.0
THOC3 -10478.0


REACTOME_ATF6_ATF6_ALPHA_ACTIVATES_CHAPERONE_GENES

REACTOME_ATF6_ATF6_ALPHA_ACTIVATES_CHAPERONE_GENES
624
set REACTOME_ATF6_ATF6_ALPHA_ACTIVATES_CHAPERONE_GENES
setSize 10
pANOVA 0.00325
s.dist 0.538
p.adjustANOVA 0.3



Top enriched genes

Top 20 genes
GeneID Gene Rank
DDIT3 10329
ATF4 10029
CALR 9928
HSP90B1 9489
XBP1 9400
HSPA5 8402
NFYB 4893
ATF6 75
NFYC -782
NFYA -1006

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DDIT3 10329
ATF4 10029
CALR 9928
HSP90B1 9489
XBP1 9400
HSPA5 8402
NFYB 4893
ATF6 75
NFYC -782
NFYA -1006


REACTOME_INTERLEUKIN_10_SIGNALING

REACTOME_INTERLEUKIN_10_SIGNALING
1039
set REACTOME_INTERLEUKIN_10_SIGNALING
setSize 43
pANOVA 0.00333
s.dist 0.259
p.adjustANOVA 0.3



Top enriched genes

Top 20 genes
GeneID Gene Rank
CCL4 11009
CSF3 10953
CCL22 10754
CCL3 10706
IL10 10644
IL1B 10591
TNFRSF1A 10393
CCL2 10003
FCER2 9480
IL1RN 9398
CCR2 9002
CCL19 8694
IL18 8424
CCR1 7845
CD86 7642
JAK1 7274
CSF2 7180
IL6 6398
CXCL1 5682
STAT3 5078

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CCL4 11009
CSF3 10953
CCL22 10754
CCL3 10706
IL10 10644
IL1B 10591
TNFRSF1A 10393
CCL2 10003
FCER2 9480
IL1RN 9398
CCR2 9002
CCL19 8694
IL18 8424
CCR1 7845
CD86 7642
JAK1 7274
CSF2 7180
IL6 6398
CXCL1 5682
STAT3 5078
CXCL10 4844
IL12B 4601
CSF1 3905
CCR5 3606
ICAM1 3541
CCL5 3112
IL1R2 2653
IL10RB 2515
IL1R1 1205
PTAFR 993
CXCL8 -272
CXCL2 -2422
IL1A -3636
CD80 -3642
PTGS2 -4452
IL12A -5279
IL10RA -6917
CCL20 -7108
TNFRSF1B -7491
TYK2 -8257
TNF -9561
LIF -9653
FPR1 -10227


REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS
536
set REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS
setSize 55
pANOVA 0.00349
s.dist -0.228
p.adjustANOVA 0.3



Top enriched genes

Top 20 genes
GeneID Gene Rank
HSPG2 -9741
LAMB2 -9709
COL5A1 -9077
FN1 -8702
COL10A1 -8545
DAG1 -8390
ITGB4 -8213
COL4A2 -8097
TNC -7901
COL1A2 -7661
COL11A2 -7521
VTN -7504
LAMB3 -7341
ITGB1 -7226
LAMA5 -6715
AGRN -6505
NTN4 -6442
TTR -5794
ITGB5 -5517
LAMA1 -5500

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
HSPG2 -9741
LAMB2 -9709
COL5A1 -9077
FN1 -8702
COL10A1 -8545
DAG1 -8390
ITGB4 -8213
COL4A2 -8097
TNC -7901
COL1A2 -7661
COL11A2 -7521
VTN -7504
LAMB3 -7341
ITGB1 -7226
LAMA5 -6715
AGRN -6505
NTN4 -6442
TTR -5794
ITGB5 -5517
LAMA1 -5500
COL4A1 -5280
LAMC1 -5276
LAMA4 -5112
SDC1 -4653
LAMC3 -4482
LAMC2 -3737
PDGFA -3698
SDC2 -3334
COL2A1 -2800
TGFB1 -2633
SDC4 -2326
COL3A1 -2263
THBS1 -1782
DDR2 -1032
PRKCA -1005
COL1A1 -337
ITGB3 238
LAMB1 548
COL4A4 826
ITGAV 1347
PDGFB 1355
COL4A3 1789
NRXN1 2002
COL5A2 2274
ITGA2 2292
LAMA3 2328
LAMA2 3285
COL11A1 4075
ACTN1 5339
COL5A3 6596
ITGA6 6711
TRAPPC4 7221
DDR1 7894
SDC3 8535
FGF2 8790


REACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53

REACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53
591
set REACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53
setSize 351
pANOVA 0.00354
s.dist 0.0906
p.adjustANOVA 0.3



Top enriched genes

Top 20 genes
GeneID Gene Rank
SFN 11067
POU4F2 10453
POLR2J 10348
MDM4 10271
KMT5A 10116
ZNF385A 10114
TP53INP1 10050
TNFRSF10B 10045
NDRG1 9985
BTG2 9976
AGO1 9963
RGCC 9866
DDB2 9641
CSNK2A1 9436
GTF2H4 9368
UBC 9309
TNRC6C 9134
CHEK2 9124
YWHAG 9119
COX6A1 8978

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SFN 11067
POU4F2 10453
POLR2J 10348
MDM4 10271
KMT5A 10116
ZNF385A 10114
TP53INP1 10050
TNFRSF10B 10045
NDRG1 9985
BTG2 9976
AGO1 9963
RGCC 9866
DDB2 9641
CSNK2A1 9436
GTF2H4 9368
UBC 9309
TNRC6C 9134
CHEK2 9124
YWHAG 9119
COX6A1 8978
TP53RK 8879
MAPK14 8871
PIP4P1 8835
SUPT16H 8758
AURKB 8750
NLRC4 8689
ARID3A 8647
TAF12 8360
TAF15 8316
LAMTOR5 8305
GATAD2B 8274
TAF10 8273
CASP6 8201
CHEK1 8188
RRAGC 8126
ELOC 8110
POLR2K 8079
TXN 8058
CASP10 8044
PPP1R13L 7969
CCNH 7926
CCNT2 7921
SCO2 7917
POLR2G 7915
RBBP8 7903
TBP 7840
SESN2 7821
COX5A 7752
BRCA1 7745
COX7C 7723
GTF2H3 7687
BCL2L14 7659
RRAGD 7614
LAMTOR1 7542
CRADD 7524
FOS 7498
CNOT6L 7441
YWHAZ 7406
CDKN2A 7234
TNRC6B 7207
BBC3 7198
KAT6A 7094
TAF2 6977
RPA2 6972
CDKN1A 6874
UBB 6789
KAT5 6721
SSRP1 6669
GLS2 6625
SGK1 6578
TP53BP2 6552
CASP1 6508
BRIP1 6400
GTF2H1 6356
BNIP3L 6353
TPX2 6287
GATAD2A 6286
PML 6123
GPX2 6120
TXNRD1 6118
PRDM1 5983
PRMT1 5915
CCNA2 5893
LAMTOR3 5852
CDK13 5829
RRM2B 5824
ZNF420 5789
TAF6 5764
CNOT8 5687
PHF20 5589
PRKAG3 5577
USP2 5562
RRAGA 5464
TP53I3 5432
PPP2R5C 5344
MLST8 5299
RAD9B 5280
SUPT4H1 5232
TAF5 5215
DAXX 5185
PLAGL1 5077
HDAC2 4870
TAF9 4726
CDC25C 4680
POLR2C 4490
BLM 4469
NELFB 4377
RAD9A 4283
COX4I1 4271
FANCC 4252
CNOT10 4171
TACO1 4122
COX8A 4100
CDK12 4098
RFC4 4043
FANCI 4015
MAP2K6 3981
CCNA1 3809
RBBP4 3683
CCNB1 3644
COX16 3575
RMI2 3488
COX18 3478
POLR2D 3460
RPA3 3436
MDM2 3366
BCL6 3281
RAD1 3276
MAPKAP1 3229
ATRIP 3175
POLR2H 3166
CSNK2B 3095
CHD4 3069
TFDP2 3041
E2F4 3024
RBL2 3020
PPP2R1B 3019
NBN 2994
ATM 2939
POLR2L 2911
CDK2 2846
TTC5 2790
TRIAP1 2684
PRDX2 2680
PMAIP1 2645
CNOT4 2541
POLR2F 2465
EXO1 2374
PRKAA2 2357
RABGGTA 2353
BARD1 2305
COX19 2299
CDK5 2270
RNF34 2232
LRPPRC 2184
TCEA1 2151
RBL1 2141
UBA52 2012
CHD3 2001
PLK3 1991
RAD17 1851
TNFRSF10A 1837
CCNK 1765
MLH1 1703
LAMTOR2 1697
PIP4K2C 1689
MEAF6 1671
PCNA 1644
ERCC3 1635
PRKAG1 1552
COX6B1 1526
RHNO1 1516
PLK2 1439
SESN1 1418
TIGAR 1400
GTF2F2 1394
TSC1 1353
RAD50 1302
AKT3 1256
PPP2R1A 1180
HIPK2 1112
TAF3 983
TAF7 940
YWHAB 890
SLC38A9 889
TOPBP1 811
CNOT7 781
GTF2H5 738
DDIT4 723
COX6C 721
COX11 710
IGFBP3 698
RPA1 693
MBD3 675
MRE11 513
PIP4K2A 468
GLS 388
PRKAB2 361
PRMT5 288
PRR5 286
MSH2 230
POU4F1 206
TP73 82
TMEM219 27
YWHAE -5
MTA2 -172
HUS1 -198
MDC1 -207
RAD51D -208
PIN1 -261
ELL -297
PTEN -311
GPI -315
RICTOR -316
TOP3A -380
GSR -469
COX14 -553
YWHAH -558
CSNK2A2 -630
PRKAA1 -632
TP63 -648
HIPK1 -729
POLR2I -759
AIFM2 -821
PPP1R13B -913
CNOT2 -993
RFFL -1022
BRPF3 -1053
AURKA -1179
BANP -1186
PRDX1 -1220
CNOT11 -1226
MNAT1 -1296
NELFE -1369
CCNT1 -1380
CDK1 -1393
STK11 -1549
PCBP4 -1590
PRKAG2 -1597
SESN3 -1659
BID -1669
TNKS1BP1 -1767
PIDD1 -1890
POLR2E -1933
SMYD2 -2032
NDUFA4 -2120
BRPF1 -2135
CDK7 -2169
POLR2B -2223
ELOB -2229
CDKN1B -2241
E2F1 -2318
SETD9 -2377
RFC2 -2427
CREBBP -2481
YWHAQ -2486
GADD45A -2524
APAF1 -2526
NPM1 -2625
PRDX5 -2641
RFC3 -2687
ATF2 -3071
PRELID3A -3127
WRN -3171
AGO3 -3181
ELOA2 -3210
TP53 -3217
CCNE2 -3238
CENPJ -3375
MAPK11 -3380
PERP -3590
PPP2CB -3621
RHEB -3638
PPP2CA -3664
CYCS -3692
CNOT6 -3696
FAS -3797
E2F8 -3815
BIRC5 -3821
ATR -3882
AGO4 -3899
COX20 -3971
RMI1 -3986
TAF4B -3992
BRD7 -4075
DYRK2 -4078
CDK9 -4087
NELFCD -4105
POLR2A -4110
ING2 -4382
GTF2F1 -4385
JMY -4420
CARM1 -4597
TAF13 -4616
TNFRSF10C -4687
TFDP1 -4875
RABGGTB -4877
EHMT1 -4884
CASP2 -5043
RPTOR -5084
FANCD2 -5203
DNA2 -5244
SUPT5H -5253
AKT1 -5452
JUN -5493
CCNG1 -5535
TNRC6A -5770
TAF4 -5861
AGO2 -5866
NOC2L -5901
PMS2 -5933
PIP4K2B -5978
MAPKAPK5 -6037
RFC5 -6073
TAF11 -6169
CNOT9 -6197
ERCC2 -6258
RPS27A -6304
NELFA -6315
EP300 -6335
COX5B -6340
MOV10 -6482
PRKAB1 -6527
EHMT2 -6860
USP7 -6910
E2F7 -6999
AKT2 -7272
NUAK1 -7517
BAX -7528
LAMTOR4 -7644
BRD1 -7653
HDAC1 -7826
MTOR -7846
CDK5R1 -7866
CCNE1 -7915
TAF1L -8100
COX7A2L -8264
CNOT1 -8267
SCO1 -8311
ING5 -8419
TNFRSF10D -8639
CTDP1 -8697
TSC2 -8830
CNOT3 -9069
SURF1 -9100
ELOA -9263
L3MBTL1 -9323
STEAP3 -9350
PRELID1 -9454
TP53AIP1 -9930
PDPK1 -10016


REACTOME_NGF_STIMULATED_TRANSCRIPTION

REACTOME_NGF_STIMULATED_TRANSCRIPTION
1422
set REACTOME_NGF_STIMULATED_TRANSCRIPTION
setSize 38
pANOVA 0.00365
s.dist 0.272
p.adjustANOVA 0.3



Top enriched genes

Top 20 genes
GeneID Gene Rank
MEF2D 10534
VGF 9613
RRAD 9136
ID3 9068
TRIB1 8656
EGR3 8184
TCF12 7895
CDK5R2 7867
DNM2 7734
FOS 7498
FOSB 7020
REST 6679
NAB1 6600
SGK1 6578
ID1 6402
SRF 6273
ID4 5102
F3 4681
NAB2 4415
ASCL1 4233

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MEF2D 10534
VGF 9613
RRAD 9136
ID3 9068
TRIB1 8656
EGR3 8184
TCF12 7895
CDK5R2 7867
DNM2 7734
FOS 7498
FOSB 7020
REST 6679
NAB1 6600
SGK1 6578
ID1 6402
SRF 6273
ID4 5102
F3 4681
NAB2 4415
ASCL1 4233
LYL1 4045
EGR2 3735
ARC 3190
CHD4 3069
CDK5 2270
EGR4 1870
JUNB 420
CREB1 418
FOSL1 -127
ATF1 -1525
EGR1 -2756
ID2 -2878
ATF2 -3071
TPH1 -4310
SH3GL3 -4922
EP300 -6335
CDK5R1 -7866
JUND -9442


REACTOME_VISUAL_PHOTOTRANSDUCTION

REACTOME_VISUAL_PHOTOTRANSDUCTION
473
set REACTOME_VISUAL_PHOTOTRANSDUCTION
setSize 93
pANOVA 0.00397
s.dist -0.173
p.adjustANOVA 0.31



Top enriched genes

Top 20 genes
GeneID Gene Rank
RBP3 -10727
RHO -10685
AKR1B10 -10578
APOA4 -10210
GPIHBP1 -10056
HSPG2 -9741
RLBP1 -9618
GNGT1 -9405
AKR1C4 -8936
CLPS -8717
OPN1SW -8708
CNGB1 -8680
AKR1C3 -8456
PDE6B -8393
RDH11 -8089
BCO1 -7910
APOC3 -7735
GRK7 -7629
GPC1 -7493
LRP1 -7472

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RBP3 -10727
RHO -10685
AKR1B10 -10578
APOA4 -10210
GPIHBP1 -10056
HSPG2 -9741
RLBP1 -9618
GNGT1 -9405
AKR1C4 -8936
CLPS -8717
OPN1SW -8708
CNGB1 -8680
AKR1C3 -8456
PDE6B -8393
RDH11 -8089
BCO1 -7910
APOC3 -7735
GRK7 -7629
GPC1 -7493
LRP1 -7472
CNGA1 -7427
RBP2 -7399
LRP10 -7034
RDH16 -6973
AGRN -6505
SDR9C7 -6383
PLB1 -6123
TTR -5794
RDH12 -5758
CYP4V2 -5659
LRP12 -5633
GRK1 -5591
LDLR -5273
LRP8 -5192
STRA6 -4837
SDC1 -4653
GUCA1A -4319
ABCA4 -3573
SDC2 -3334
MYO7A -3290
GUCA1B -3198
SLC24A1 -2588
NMT1 -2584
FNTA -2544
SDC4 -2326
PRKCQ -2320
METAP1 -2250
APOB -2139
APOA2 -1626
PDE6G -1427
RBP4 -1246
GUCY2D -1175
GPC6 -1036
PRKCA -1005
GUCA1C -128
NAPEPLD -86
FNTB 293
APOC2 369
RPE65 579
DHRS3 631
AKR1C1 687
PNLIP 754
LRP2 968
RDH5 1292
RCVRN 1405
RDH8 1419
APOA1 1486
GNB1 1983
BCO2 2235
CAMKMT 2247
GNAT1 2651
GRK4 2976
RBP1 3022
RGS9 3180
GPC5 4518
NMT2 4585
CALM1 4775
RDH10 5237
METAP2 5316
HSD17B1 5894
GPC2 6115
HSD17B6 6362
GNB5 6406
APOE 6788
LRAT 6987
RGS9BP 7078
SAG 7158
RETSAT 7361
PDE6A 8154
APOM 8446
LPL 8455
SDC3 8535
DHRS9 10475


REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION
116
set REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION
setSize 291
pANOVA 0.00432
s.dist -0.0972
p.adjustANOVA 0.31



Top enriched genes

Top 20 genes
GeneID Gene Rank
KLKB1 -10568
PRSS1 -10536
CTRB2 -10525
CTRB1 -10356
PECAM1 -10282
BMP1 -10241
DMP1 -10239
MMP8 -10228
COL13A1 -9833
MMP1 -9829
HSPG2 -9741
LAMB2 -9709
DSPP -9686
FBLN1 -9591
FBN3 -9468
CAPN14 -9370
OPTC -9160
PXDN -9109
COL5A1 -9077
CAPN10 -9038

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
KLKB1 -10568
PRSS1 -10536
CTRB2 -10525
CTRB1 -10356
PECAM1 -10282
BMP1 -10241
DMP1 -10239
MMP8 -10228
COL13A1 -9833
MMP1 -9829
HSPG2 -9741
LAMB2 -9709
DSPP -9686
FBLN1 -9591
FBN3 -9468
CAPN14 -9370
OPTC -9160
PXDN -9109
COL5A1 -9077
CAPN10 -9038
COL27A1 -8994
GDF5 -8987
SERPINE1 -8985
CAPN5 -8979
CAPN13 -8933
PLOD1 -8835
ADAMTS14 -8822
LOXL4 -8741
FN1 -8702
MMP15 -8683
ADAMTS2 -8610
COL6A3 -8576
MATN1 -8552
COL10A1 -8545
COL6A2 -8485
PTPRS -8477
DAG1 -8390
CAPN3 -8292
MMP17 -8276
ITGB4 -8213
SCUBE1 -8106
COL4A2 -8097
ITGA3 -8036
TNC -7901
CAPNS2 -7847
JAM2 -7693
COL1A2 -7661
ITGA10 -7550
COL11A2 -7521
VTN -7504
COL6A1 -7455
LAMB3 -7341
ITGB1 -7226
SERPINH1 -7183
COL8A2 -6928
ACAN -6904
ADAM9 -6889
FBLN2 -6808
LAMA5 -6715
FURIN -6560
AGRN -6505
NTN4 -6442
LOXL2 -6406
CMA1 -6402
FMOD -6360
COL18A1 -6292
ITGA7 -6252
ITGA9 -5982
VCAM1 -5924
MFAP2 -5889
P3H2 -5864
TTR -5794
LTBP2 -5753
CAPN9 -5725
EMILIN1 -5711
ITGA11 -5696
TNXB -5576
ITGB5 -5517
LAMA1 -5500
COL20A1 -5300
COL4A1 -5280
LAMC1 -5276
FGB -5252
NCSTN -5119
LAMA4 -5112
ADAMTS16 -5047
DCN -5025
FBN1 -4995
CAPN8 -4671
PHYKPL -4660
SDC1 -4653
COL26A1 -4630
NCAM1 -4575
LAMC3 -4482
HTRA1 -4324
COL17A1 -4260
FBN2 -4213
CAPN15 -4032
BSG -3954
ADAM15 -3944
MUSK -3786
LAMC2 -3737
A2M -3721
PDGFA -3698
COL21A1 -3632
ITGB2 -3578
MMP12 -3457
SDC2 -3334
COL22A1 -3311
KLK2 -3146
CAST -2994
SCUBE3 -2977
MMP7 -2969
CASP3 -2880
MMP3 -2849
PLEC -2834
COL16A1 -2805
COL2A1 -2800
MMP2 -2667
PLOD2 -2636
TGFB1 -2633
NID2 -2592
COL7A1 -2472
SDC4 -2326
COL3A1 -2263
CAPN11 -2252
ITGB6 -2128
CAPN2 -2117
COL24A1 -2034
MFAP5 -1952
MATN4 -1861
BMP10 -1850
TMPRSS6 -1844
PCOLCE2 -1802
THBS1 -1782
ADAMTS3 -1738
ITGA8 -1700
IBSP -1404
DST -1346
P3H1 -1305
CEACAM1 -1243
DDR2 -1032
PRKCA -1005
JAM3 -903
LOXL3 -801
MMP25 -780
MMP24 -724
CAPN7 -716
HAPLN1 -662
CEACAM8 -649
MMP10 -569
COLGALT1 -508
PLOD3 -495
SH3PXD2A -475
COL1A1 -337
P4HA2 -300
COL14A1 -270
TGFB3 -188
ADAM17 -76
P3H3 171
LOX 200
TNN 213
ITGB3 238
CDH1 279
CAPNS1 346
LAMB1 548
COL19A1 564
COL28A1 624
LTBP1 638
COL23A1 782
FBLN5 806
COL4A4 826
CTSL 886
P4HA1 1055
CTSS 1093
ADAM8 1152
EMILIN3 1192
SPARC 1226
ITGAX 1235
COL8A1 1239
COL9A2 1244
EFEMP1 1264
COLGALT2 1303
ITGAV 1347
PDGFB 1355
LTBP4 1402
ITGAL 1490
APP 1659
MMP20 1683
TLL2 1736
MMP11 1757
COL4A3 1789
ADAM12 1892
CD44 1970
ITGAD 1981
NRXN1 2002
CTSB 2023
CAPN1 2045
ITGB8 2101
FGG 2131
ADAMTS8 2163
BMP7 2195
MMP13 2198
VCAN 2217
LOXL1 2254
COL5A2 2274
VWF 2291
ITGA2 2292
MADCAM1 2304
LAMA3 2328
ITGA4 2339
COL6A5 2361
NID1 2763
ADAMTS18 2801
TNR 2872
MMP14 2893
ADAMTS1 2922
ADAMTS9 2931
TGFB2 2970
SPOCK3 3028
TLL1 3083
LAMA2 3285
COL9A1 3419
ICAM4 3430
ITGAM 3504
ITGA1 3507
TIMP2 3529
ICAM1 3541
ADAM10 3627
ADAM19 3660
LTBP3 3775
ADAMTS5 3878
P4HA3 3954
COL11A1 4075
BMP4 4149
PSEN1 4160
ITGA2B 4246
MFAP3 4360
SPP1 4654
ASPN 4869
CD47 5035
CAPN12 5119
COL15A1 5146
ACTN1 5339
ADAMTS4 5667
CD151 5693
KDR 6011
ELN 6199
COL12A1 6255
NCAN 6282
ICAM2 6330
COL25A1 6365
COL6A6 6433
COL5A3 6596
ITGA6 6711
MMP16 6806
CRTAP 6909
LRP4 7053
ITGAE 7188
TRAPPC4 7221
MATN3 7230
PLG 7350
PCOLCE 7606
BMP2 7789
PPIB 7858
DDR1 7894
FGA 8162
ITGB7 8179
LUM 8475
SDC3 8535
MMP9 8639
MMP19 8726
F11R 8768
FGF2 8790
KLK7 8874
EMILIN2 8948
COMP 8986
ICAM3 9384
ITGA5 9566
CTSK 9728
ICAM5 9814
CTSV 9903
P4HB 9931
BCAN 9933
COL9A3 10111
EFEMP2 10580
CTSD 10690
ELANE 10883
CTSG 11021
CEACAM6 11063
MFAP4 11107


REACTOME_INTERLEUKIN_1_SIGNALING

REACTOME_INTERLEUKIN_1_SIGNALING
1401
set REACTOME_INTERLEUKIN_1_SIGNALING
setSize 110
pANOVA 0.00447
s.dist 0.157
p.adjustANOVA 0.31



Top enriched genes

Top 20 genes
GeneID Gene Rank
IL1B 10591
NKIRAS2 10063
PSMA1 10043
NOD1 9966
SAA1 9781
RBX1 9765
UBE2N 9761
PSMA6 9587
PSMB10 9558
IRAK3 9452
IL1RN 9398
PELI3 9344
UBC 9309
PSMD13 8956
MAP2K1 8942
MAP3K8 8362
UBE2V1 8231
PSMB7 8153
MYD88 7749
S100B 7344

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
IL1B 10591
NKIRAS2 10063
PSMA1 10043
NOD1 9966
SAA1 9781
RBX1 9765
UBE2N 9761
PSMA6 9587
PSMB10 9558
IRAK3 9452
IL1RN 9398
PELI3 9344
UBC 9309
PSMD13 8956
MAP2K1 8942
MAP3K8 8362
UBE2V1 8231
PSMB7 8153
MYD88 7749
S100B 7344
NKIRAS1 7269
TRAF6 7001
MAP3K7 6877
FBXW11 6800
UBB 6789
PELI2 6745
PSMB4 6341
CASP8 6261
CUL1 6104
HMGB1 5972
PSMD12 5712
PSMD3 5632
PSME3 5531
PSMB1 5505
PSMA3 5324
PSMC1 5255
MAP3K3 5203
PSMA2 5121
PSMC3 4952
SQSTM1 4813
NOD2 4792
PELI1 4599
USP14 4516
PSMC4 4459
PSMA7 3991
MAP2K6 3981
PSMD14 3675
LRRC14 3274
IRAK2 2933
PSMC5 2665
IL1R2 2653
UBA52 2012
NFKB2 1809
PSME4 1702
APP 1659
PSME2 1571
MAP2K4 1464
S100A12 1431
NLRC5 1429
IL1R1 1205
PSMD7 646
PSMD6 620
PSMB3 544
SEM1 292
IRAK4 129
SKP1 51
PSMC6 -296
PSMA4 -401
PSMD11 -439
PSMD2 -547
NFKBIB -565
PSMB2 -611
PSMA8 -621
PSMD5 -828
PSMF1 -878
TOLLIP -904
PSMB8 -1223
RELA -1562
PSMD4 -1623
PSMA5 -1800
CHUK -1813
RIPK2 -2148
PSMD9 -2254
BTRC -2464
PSMB5 -2516
TIFA -2673
IL1RAP -2793
IKBIP -2982
TP53 -3217
AGER -3463
IL1A -3636
N4BP1 -3816
PSMB9 -3852
NFKB1 -3915
NLRX1 -4336
PSMC2 -4425
TNIP2 -4587
TAB2 -5041
USP18 -5104
PSMD1 -5434
NFKBIA -5622
TAB1 -5743
PSME1 -5997
PSMB6 -6154
RPS27A -6304
IKBKB -7286
PSMD8 -7295
TRAF2 -8333
ALPK1 -9031
PSMB11 -10167


REACTOME_TRANSCRIPTIONAL_REGULATION_OF_TESTIS_DIFFERENTIATION

REACTOME_TRANSCRIPTIONAL_REGULATION_OF_TESTIS_DIFFERENTIATION
1549
set REACTOME_TRANSCRIPTIONAL_REGULATION_OF_TESTIS_DIFFERENTIATION
setSize 12
pANOVA 0.00487
s.dist 0.469
p.adjustANOVA 0.31



Top enriched genes

Top 20 genes
GeneID Gene Rank
SOX9 8791
AMH 8603
NR5A1 8361
WT1 7882
GATA4 7532
PTGDS 6871
DHH 4773
WNT4 3923
DMRT1 3624
FOXL2 2954
ZFPM2 2281
FGF9 -1681

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SOX9 8791
AMH 8603
NR5A1 8361
WT1 7882
GATA4 7532
PTGDS 6871
DHH 4773
WNT4 3923
DMRT1 3624
FOXL2 2954
ZFPM2 2281
FGF9 -1681


REACTOME_KERATINIZATION

REACTOME_KERATINIZATION
1073
set REACTOME_KERATINIZATION
setSize 210
pANOVA 0.00491
s.dist -0.113
p.adjustANOVA 0.31



Top enriched genes

Top 20 genes
GeneID Gene Rank
KRTAP10-9 -10827
KRTAP10-2 -10757
KRTAP8-1 -10746
KRT39 -10665
KRTAP5-9 -10645
KRTAP23-1 -10583
KRT79 -10554
LCE5A -10527
KRTAP5-8 -10526
KRTAP15-1 -10422
KRTAP10-8 -10304
PKP3 -10266
KRT82 -10255
KRTAP3-1 -10130
KRTAP4-7 -10118
LCE1F -9961
SPRR2G -9856
KRT4 -9844
KRTAP9-3 -9785
KRT73 -9743

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
KRTAP10-9 -10827.0
KRTAP10-2 -10757.0
KRTAP8-1 -10746.0
KRT39 -10665.0
KRTAP5-9 -10645.0
KRTAP23-1 -10583.0
KRT79 -10554.0
LCE5A -10527.0
KRTAP5-8 -10526.0
KRTAP15-1 -10422.0
KRTAP10-8 -10304.0
PKP3 -10266.0
KRT82 -10255.0
KRTAP3-1 -10130.0
KRTAP4-7 -10118.0
LCE1F -9961.0
SPRR2G -9856.0
KRT4 -9844.0
KRTAP9-3 -9785.0
KRT73 -9743.0
KRT78 -9634.0
KRT35 -9606.0
KRT6C -9545.0
KRTAP1-3 -9516.0
KRT20 -9515.0
KRTAP13-3 -9455.0
KRTAP5-7 -9387.0
LIPK -9354.0
KRT75 -9305.0
KRTAP3-2 -9271.0
ST14 -9182.0
LIPM -9177.0
KRTAP10-3 -9076.0
KRTAP1-1 -9047.0
KRT83 -9000.0
TGM1 -8996.0
KRTAP12-2 -8937.0
KRTAP10-7 -8799.0
PCSK6 -8796.0
KRT33A -8788.0
KRT1 -8695.0
KRTAP1-5 -8640.0
KRT2 -8533.0
KRTAP11-1 -8474.0
KRT13 -8416.0
KRTAP2-2 -8402.0
KRTAP19-6 -8371.0
KRT26 -8316.0
LCE1B -8303.0
KRTAP21-3 -8204.0
KRTAP4-1 -8125.0
KRT23 -8108.0
DSG4 -8026.0
JUP -7950.0
DSC1 -7921.0
KRTAP5-10 -7906.0
KRTAP4-2 -7792.0
KRT15 -7718.0
KRT80 -7666.0
KRTAP10-10 -7652.0
KRT71 -7559.0
KRTAP4-3 -7335.0
CDSN -7331.0
KAZN -7176.0
KRT85 -7077.0
KRTAP6-1 -7075.0
KRTAP10-4 -6753.0
KRT28 -6711.0
FURIN -6560.0
LCE3E -6547.5
KRTAP19-5 -6531.0
PKP1 -6481.0
SPRR1B -6318.0
KRTAP17-1 -6311.0
KRTAP13-4 -6280.0
KRT31 -6271.0
KRTAP16-1 -6209.0
PPL -6207.0
KRTAP13-2 -6166.0
KRT27 -6012.0
FLG -5837.0
LCE2C -5779.0
CELA2A -5691.0
KRT81 -5563.0
KRTAP19-8 -5438.0
KRT3 -5419.0
KRTAP5-11 -5354.0
KRT37 -5299.0
KLK8 -5157.0
KRT24 -5075.0
DSP -5072.0
LCE1E -4956.0
KRTAP22-1 -4642.0
KRTAP19-2 -4432.0
KRT76 -4378.0
KRTAP27-1 -3999.0
PERP -3590.0
PKP2 -3343.0
KRT5 -3264.0
KRTAP10-11 -3029.0
KLK5 -2672.0
KRTAP6-2 -2650.0
KRTAP4-5 -2646.0
KRT77 -2598.0
KRTAP9-2 -2188.0
KRT12 -2187.0
KRT6B -1884.0
KRT32 -1806.0
KRTAP26-1 -1724.0
LCE2D -1566.0
KRT86 -1526.0
KRT9 -1425.0
PKP4 -1411.0
SPINK5 -1388.0
KRTAP12-3 -979.0
KRT74 -721.0
KRT18 -612.0
KRTAP2-4 -596.0
RPTN -591.0
KRTAP19-4 -522.0
KRT36 -267.0
KRTAP4-8 14.0
KRT84 121.0
KRTAP9-1 232.0
CAPNS1 346.0
SPRR2A 599.0
PI3 735.0
KRTAP20-2 1062.0
LIPJ 1143.0
KRTAP5-5 1275.0
KRT7 1305.0
PRSS8 1328.0
SPRR2D 1545.0
KRTAP3-3 1577.0
KRTAP4-4 1821.0
CAPN1 2045.0
KRTAP19-7 2439.0
TCHH 2486.0
KRT40 2497.0
KRTAP20-1 2762.0
KRTAP24-1 2989.0
SPRR2E 4291.0
EVPL 4339.0
LCE4A 4496.0
KRTAP9-4 4768.0
LCE3B 4860.0
TGM5 5154.0
KRTAP19-1 5657.0
CASP14 5903.0
KRTAP9-9 6084.0
KRTAP6-3 6088.0
KRTAP21-2 6168.0
DSC2 6216.0
DSG3 6312.0
LCE1A 6390.0
KRT8 6587.0
KRTAP5-3 6606.0
LELP1 6671.0
KRTAP4-6 6742.0
KRTAP10-1 6889.0
KRTAP25-1 6976.0
DSG1 7175.0
KRT34 7240.0
KRTAP10-12 7252.0
KRT33B 7284.0
LCE3D 7363.0
KLK13 7417.0
KRTAP5-2 7506.0
KRTAP2-1 7667.0
LCE1C 7700.0
DSG2 7765.0
KRT19 7850.0
SPRR1A 7942.0
KRT10 8001.0
KRTAP21-1 8085.0
DSC3 8191.0
KRT14 8221.0
KRTAP19-3 8314.0
KRTAP10-5 8397.0
KRT38 8437.0
SPINK9 8453.0
KRTAP12-4 8611.0
KRT25 8619.0
LCE6A 8716.0
LCE2B 9040.0
LIPN 9054.0
SPRR3 9079.0
KLK12 9114.0
SPRR2F 9138.0
KRTAP5-4 9383.0
KRTAP5-1 9549.0
IVL 9826.0
KRT6A 9965.0
LCE2A 10005.0
KLK14 10147.0
KRT72 10213.0
KRTAP2-3 10235.0
KRTAP13-1 10336.0
KRTAP10-6 10368.0
KRTAP12-1 10415.0
CSTA 10431.0
KRTAP9-6 10457.0
KRTAP1-4 10595.0
LCE3A 10654.0
KRT17 10702.0
SPINK6 10820.0
KRT16 10905.0
KRTAP29-1 10927.0
KRTAP5-6 10939.0
KRTAP4-11 10988.0


REACTOME_ECM_PROTEOGLYCANS

REACTOME_ECM_PROTEOGLYCANS
537
set REACTOME_ECM_PROTEOGLYCANS
setSize 73
pANOVA 0.00497
s.dist -0.19
p.adjustANOVA 0.31



Top enriched genes

Top 20 genes
GeneID Gene Rank
DMP1 -10239
HSPG2 -9741
LAMB2 -9709
DSPP -9686
COL5A1 -9077
SERPINE1 -8985
FN1 -8702
COL6A3 -8576
MATN1 -8552
COL6A2 -8485
PTPRS -8477
DAG1 -8390
COL4A2 -8097
TNC -7901
COL1A2 -7661
VTN -7504
COL6A1 -7455
ITGB1 -7226
ACAN -6904
LAMA5 -6715

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DMP1 -10239
HSPG2 -9741
LAMB2 -9709
DSPP -9686
COL5A1 -9077
SERPINE1 -8985
FN1 -8702
COL6A3 -8576
MATN1 -8552
COL6A2 -8485
PTPRS -8477
DAG1 -8390
COL4A2 -8097
TNC -7901
COL1A2 -7661
VTN -7504
COL6A1 -7455
ITGB1 -7226
ACAN -6904
LAMA5 -6715
AGRN -6505
FMOD -6360
ITGA7 -6252
ITGA9 -5982
TNXB -5576
ITGB5 -5517
LAMA1 -5500
COL4A1 -5280
LAMC1 -5276
LAMA4 -5112
DCN -5025
NCAM1 -4575
MUSK -3786
COL2A1 -2800
TGFB1 -2633
COL3A1 -2263
ITGB6 -2128
MATN4 -1861
ITGA8 -1700
IBSP -1404
HAPLN1 -662
COL1A1 -337
TGFB3 -188
TNN 213
ITGB3 238
LAMB1 548
COL4A4 826
SPARC 1226
ITGAX 1235
COL9A2 1244
ITGAV 1347
APP 1659
COL4A3 1789
VCAN 2217
COL5A2 2274
ITGA2 2292
LAMA3 2328
COL6A5 2361
TNR 2872
TGFB2 2970
LAMA2 3285
COL9A1 3419
ITGA2B 4246
ASPN 4869
NCAN 6282
COL6A6 6433
COL5A3 6596
LRP4 7053
MATN3 7230
LUM 8475
COMP 8986
BCAN 9933
COL9A3 10111


REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING

REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING
274
set REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING
setSize 14
pANOVA 0.00509
s.dist 0.432
p.adjustANOVA 0.31



Top enriched genes

Top 20 genes
GeneID Gene Rank
AREG 10782
NRAS 10599
HBEGF 10140
GRB2 10092
SHC1 9449
KRAS 6597
EGF 5935
BTC 4240
SOS1 3727
TGFA 3350
EREG 3323
EPGN 2433
EGFR -4408
HRAS -7398

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
AREG 10782
NRAS 10599
HBEGF 10140
GRB2 10092
SHC1 9449
KRAS 6597
EGF 5935
BTC 4240
SOS1 3727
TGFA 3350
EREG 3323
EPGN 2433
EGFR -4408
HRAS -7398


REACTOME_LAMININ_INTERACTIONS

REACTOME_LAMININ_INTERACTIONS
534
set REACTOME_LAMININ_INTERACTIONS
setSize 28
pANOVA 0.00659
s.dist -0.297
p.adjustANOVA 0.38



Top enriched genes

Top 20 genes
GeneID Gene Rank
HSPG2 -9741
LAMB2 -9709
ITGB4 -8213
COL4A2 -8097
ITGA3 -8036
LAMB3 -7341
ITGB1 -7226
LAMA5 -6715
COL18A1 -6292
ITGA7 -6252
LAMA1 -5500
COL4A1 -5280
LAMC1 -5276
LAMA4 -5112
LAMC3 -4482
LAMC2 -3737
NID2 -2592
COL7A1 -2472
LAMB1 548
COL4A4 826

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
HSPG2 -9741
LAMB2 -9709
ITGB4 -8213
COL4A2 -8097
ITGA3 -8036
LAMB3 -7341
ITGB1 -7226
LAMA5 -6715
COL18A1 -6292
ITGA7 -6252
LAMA1 -5500
COL4A1 -5280
LAMC1 -5276
LAMA4 -5112
LAMC3 -4482
LAMC2 -3737
NID2 -2592
COL7A1 -2472
LAMB1 548
COL4A4 826
ITGAV 1347
COL4A3 1789
ITGA2 2292
LAMA3 2328
NID1 2763
LAMA2 3285
ITGA1 3507
ITGA6 6711


REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING

REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING
1596
set REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING
setSize 11
pANOVA 0.00717
s.dist 0.468
p.adjustANOVA 0.38



Top enriched genes

Top 20 genes
GeneID Gene Rank
TLR9 10408
UBE2N 9761
UBC 9309
UBE2V1 8231
MYD88 7749
TRAF6 7001
UBB 6789
IRF7 3360
UBA52 2012
IRAK4 129
RPS27A -6304

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TLR9 10408
UBE2N 9761
UBC 9309
UBE2V1 8231
MYD88 7749
TRAF6 7001
UBB 6789
IRF7 3360
UBA52 2012
IRAK4 129
RPS27A -6304


REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_PHOSPHORYLATION

REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_PHOSPHORYLATION
1069
set REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_PHOSPHORYLATION
setSize 89
pANOVA 0.00721
s.dist 0.165
p.adjustANOVA 0.38



Top enriched genes

Top 20 genes
GeneID Gene Rank
MDM4 10271
TP53INP1 10050
CSNK2A1 9436
UBC 9309
CHEK2 9124
TP53RK 8879
MAPK14 8871
SUPT16H 8758
AURKB 8750
TAF12 8360
TAF15 8316
TAF10 8273
CHEK1 8188
RBBP8 7903
TBP 7840
BRCA1 7745
TAF2 6977
RPA2 6972
UBB 6789
KAT5 6721

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MDM4 10271
TP53INP1 10050
CSNK2A1 9436
UBC 9309
CHEK2 9124
TP53RK 8879
MAPK14 8871
SUPT16H 8758
AURKB 8750
TAF12 8360
TAF15 8316
TAF10 8273
CHEK1 8188
RBBP8 7903
TBP 7840
BRCA1 7745
TAF2 6977
RPA2 6972
UBB 6789
KAT5 6721
SSRP1 6669
BRIP1 6400
TPX2 6287
CCNA2 5893
TAF6 5764
PRKAG3 5577
RAD9B 5280
TAF5 5215
TAF9 4726
BLM 4469
RAD9A 4283
RFC4 4043
CCNA1 3809
RMI2 3488
RPA3 3436
MDM2 3366
RAD1 3276
ATRIP 3175
CSNK2B 3095
NBN 2994
ATM 2939
CDK2 2846
EXO1 2374
PRKAA2 2357
BARD1 2305
CDK5 2270
UBA52 2012
PLK3 1991
RAD17 1851
PRKAG1 1552
RHNO1 1516
RAD50 1302
HIPK2 1112
TAF3 983
TAF7 940
TOPBP1 811
RPA1 693
MRE11 513
PRKAB2 361
HUS1 -198
PIN1 -261
TOP3A -380
CSNK2A2 -630
PRKAA1 -632
HIPK1 -729
AURKA -1179
STK11 -1549
PRKAG2 -1597
RFC2 -2427
RFC3 -2687
WRN -3171
TP53 -3217
MAPK11 -3380
ATR -3882
RMI1 -3986
TAF4B -3992
DYRK2 -4078
TAF13 -4616
DNA2 -5244
TAF4 -5861
NOC2L -5901
MAPKAPK5 -6037
RFC5 -6073
TAF11 -6169
RPS27A -6304
PRKAB1 -6527
NUAK1 -7517
CDK5R1 -7866
TAF1L -8100


REACTOME_CARGO_CONCENTRATION_IN_THE_ER

REACTOME_CARGO_CONCENTRATION_IN_THE_ER
1017
set REACTOME_CARGO_CONCENTRATION_IN_THE_ER
setSize 32
pANOVA 0.00735
s.dist 0.274
p.adjustANOVA 0.38



Top enriched genes

Top 20 genes
GeneID Gene Rank
AREG 10782
PREB 10489
CNIH1 10267
CTSZ 10153
CD59 9485
MIA2 9406
TMED10 9337
CTSC 9256
STX5 8885
SAR1B 7097
SERPINA1 6522
CNIH2 6471
SEC24A 6090
TMED2 5669
GOSR2 4150
SEC23A 3979
SEC24C 3913
TGFA 3350
SEC24D 2346
MIA3 1615

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
AREG 10782
PREB 10489
CNIH1 10267
CTSZ 10153
CD59 9485
MIA2 9406
TMED10 9337
CTSC 9256
STX5 8885
SAR1B 7097
SERPINA1 6522
CNIH2 6471
SEC24A 6090
TMED2 5669
GOSR2 4150
SEC23A 3979
SEC24C 3913
TGFA 3350
SEC24D 2346
MIA3 1615
MCFD2 1500
F5 778
SEC24B 568
LMAN1 -1248
LMAN2 -2129
GRIA1 -2202
COL7A1 -2472
CNIH3 -4478
LMAN2L -4861
SEC22B -5340
LMAN1L -7803
FOLR1 -10068


REACTOME_BLOOD_GROUP_SYSTEMS_BIOSYNTHESIS

REACTOME_BLOOD_GROUP_SYSTEMS_BIOSYNTHESIS
1428
set REACTOME_BLOOD_GROUP_SYSTEMS_BIOSYNTHESIS
setSize 21
pANOVA 0.00777
s.dist 0.336
p.adjustANOVA 0.38



Top enriched genes

Top 20 genes
GeneID Gene Rank
FUT7 10989
B3GALT2 10739
FUT4 10671
B3GALT4 10573
FUT2 9231
FUT6 9036
RHCE 8684
ST3GAL6 8160
ST3GAL3 7003
FUT11 5775
ST3GAL4 5662
RHD 4404
FUT3 3938
ST6GALNAC6 2949
FUT9 -388
FUT10 -1445
B3GALT5 -1843
B3GALT1 -3930
FUT5 -5750
B4GALNT2 -5925

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FUT7 10989
B3GALT2 10739
FUT4 10671
B3GALT4 10573
FUT2 9231
FUT6 9036
RHCE 8684
ST3GAL6 8160
ST3GAL3 7003
FUT11 5775
ST3GAL4 5662
RHD 4404
FUT3 3938
ST6GALNAC6 2949
FUT9 -388
FUT10 -1445
B3GALT5 -1843
B3GALT1 -3930
FUT5 -5750
B4GALNT2 -5925
FUT1 -7635


REACTOME_KEAP1_NFE2L2_PATHWAY

REACTOME_KEAP1_NFE2L2_PATHWAY
1604
set REACTOME_KEAP1_NFE2L2_PATHWAY
setSize 104
pANOVA 0.00821
s.dist 0.15
p.adjustANOVA 0.38



Top enriched genes

Top 20 genes
GeneID Gene Rank
MAFG 10830
PSMA1 10043
ATF4 10029
RBX1 9765
PSMA6 9587
PSMB10 9558
PRKCD 9555
CSNK2A1 9436
UBC 9309
PSMD13 8956
BACH1 8787
TRIM21 8622
PSMB7 8153
SESN2 7821
BRCA1 7745
CDKN2A 7234
CDKN1A 6874
UBB 6789
NPLOC4 6645
UBXN7 6612

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MAFG 10830
PSMA1 10043
ATF4 10029
RBX1 9765
PSMA6 9587
PSMB10 9558
PRKCD 9555
CSNK2A1 9436
UBC 9309
PSMD13 8956
BACH1 8787
TRIM21 8622
PSMB7 8153
SESN2 7821
BRCA1 7745
CDKN2A 7234
CDKN1A 6874
UBB 6789
NPLOC4 6645
UBXN7 6612
PGD 6610
PSMB4 6341
TXNRD1 6118
CUL1 6104
SKP2 6091
GSTA1 6060
GSK3B 5966
PSMD12 5712
IDH1 5637
PSMD3 5632
PSME3 5531
PSMB1 5505
PSMA3 5324
PSMC1 5255
PSMA2 5121
PSMC3 4952
SQSTM1 4813
PSMC4 4459
TALDO1 4022
PSMA7 3991
PSMD14 3675
CUL3 3602
PALB2 3433
CSNK2B 3095
PSMC5 2665
UBA52 2012
NFE2L2 1942
GCLC 1903
PSME4 1702
MAP1LC3B 1668
PSME2 1571
GSTA3 1518
SESN1 1418
HMOX1 1310
AKT3 1256
PSMD7 646
PSMD6 620
PSMB3 544
SEM1 292
MYC 235
DPP3 216
SKP1 51
PSMC6 -296
GCLM -359
PSMA4 -401
KEAP1 -423
PSMD11 -439
GSR -469
PSMD2 -547
PSMB2 -611
PSMA8 -621
CSNK2A2 -630
PSMD5 -828
PSMF1 -878
SLC7A11 -949
PRDX1 -1220
PSMB8 -1223
FBXL17 -1351
TKT -1527
PSMD4 -1623
ME1 -1670
PSMA5 -1800
NOTCH1 -1962
PSMD9 -2254
MUL1 -2387
BTRC -2464
CREBBP -2481
PSMB5 -2516
MAFK -3078
PSMB9 -3852
PSMC2 -4425
NQO1 -5433
PSMD1 -5434
AKT1 -5452
PSME1 -5997
PSMB6 -6154
RPS27A -6304
EP300 -6335
VCP -6635
UFD1 -6651
SRXN1 -6655
AKT2 -7272
PSMD8 -7295
PSMB11 -10167


REACTOME_MATURATION_OF_PROTEIN_3A

REACTOME_MATURATION_OF_PROTEIN_3A
1545
set REACTOME_MATURATION_OF_PROTEIN_3A
setSize 9
pANOVA 0.00822
s.dist 0.509
p.adjustANOVA 0.38



Top enriched genes

Top 20 genes
GeneID Gene Rank
ST3GAL2 9949
ST6GALNAC4 8259
GALNT1 7497
ST3GAL3 7003
ST6GAL1 5941
ST3GAL4 5662
ST6GALNAC2 2605
ST6GALNAC3 2507
ST3GAL1 2415

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ST3GAL2 9949
ST6GALNAC4 8259
GALNT1 7497
ST3GAL3 7003
ST6GAL1 5941
ST3GAL4 5662
ST6GALNAC2 2605
ST6GALNAC3 2507
ST3GAL1 2415


REACTOME_DIGESTION_AND_ABSORPTION

REACTOME_DIGESTION_AND_ABSORPTION
1324
set REACTOME_DIGESTION_AND_ABSORPTION
setSize 22
pANOVA 0.00825
s.dist -0.325
p.adjustANOVA 0.38



Top enriched genes

Top 20 genes
GeneID Gene Rank
GUCA2A -10531
GUCA2B -9940
NPC1L1 -9644
TREH -9198
CLPS -8717
PNLIPRP1 -7819
SLC2A2 -7419
ALPI -7285
MGAM -6409
LCT -6365
AMY2B -5683
CHIT1 -5640
CHIA -2245
PNLIPRP2 -1773
PNLIPRP3 -1381
RSC1A1 -1085
PNLIP 754
SLC5A1 1922
SLC2A5 2344
LIPF 5211

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GUCA2A -10531
GUCA2B -9940
NPC1L1 -9644
TREH -9198
CLPS -8717
PNLIPRP1 -7819
SLC2A2 -7419
ALPI -7285
MGAM -6409
LCT -6365
AMY2B -5683
CHIT1 -5640
CHIA -2245
PNLIPRP2 -1773
PNLIPRP3 -1381
RSC1A1 -1085
PNLIP 754
SLC5A1 1922
SLC2A5 2344
LIPF 5211
GUCY2C 5352
CEL 10483


REACTOME_SHC1_EVENTS_IN_ERBB2_SIGNALING

REACTOME_SHC1_EVENTS_IN_ERBB2_SIGNALING
70
set REACTOME_SHC1_EVENTS_IN_ERBB2_SIGNALING
setSize 22
pANOVA 0.00843
s.dist 0.324
p.adjustANOVA 0.38



Top enriched genes

Top 20 genes
GeneID Gene Rank
NRAS 10599
HBEGF 10140
GRB2 10092
PRKCD 9555
SHC1 9449
ERBB3 8671
NRG4 7432
KRAS 6597
EGF 5935
BTC 4240
ERBB4 4009
SOS1 3727
PTPN12 3542
EREG 3323
ERBB2 2972
NRG1 1010
PRKCA -1005
PRKCE -1750
NRG3 -1946
NRG2 -2726

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NRAS 10599
HBEGF 10140
GRB2 10092
PRKCD 9555
SHC1 9449
ERBB3 8671
NRG4 7432
KRAS 6597
EGF 5935
BTC 4240
ERBB4 4009
SOS1 3727
PTPN12 3542
EREG 3323
ERBB2 2972
NRG1 1010
PRKCA -1005
PRKCE -1750
NRG3 -1946
NRG2 -2726
EGFR -4408
HRAS -7398


REACTOME_TRANSCRIPTIONAL_REGULATION_OF_PLURIPOTENT_STEM_CELLS

REACTOME_TRANSCRIPTIONAL_REGULATION_OF_PLURIPOTENT_STEM_CELLS
815
set REACTOME_TRANSCRIPTIONAL_REGULATION_OF_PLURIPOTENT_STEM_CELLS
setSize 29
pANOVA 0.00898
s.dist 0.28
p.adjustANOVA 0.38



Top enriched genes

Top 20 genes
GeneID Gene Rank
FOXD3 9684
LIN28A 9420
HHEX 9212
FGF2 8790
DPPA4 8702
NR5A1 8361
CDX2 8165
SOX2 8009
GSC 7257
HIF3A 6609
DKK1 6553
TSC22D1 5397
PRDM14 5300
STAT3 5078
EOMES 4355
EPHA1 3642
FOXP1 3388
KLF4 3002
GATA6 2694
SMAD2 2520

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FOXD3 9684
LIN28A 9420
HHEX 9212
FGF2 8790
DPPA4 8702
NR5A1 8361
CDX2 8165
SOX2 8009
GSC 7257
HIF3A 6609
DKK1 6553
TSC22D1 5397
PRDM14 5300
STAT3 5078
EOMES 4355
EPHA1 3642
FOXP1 3388
KLF4 3002
GATA6 2694
SMAD2 2520
SMAD4 2475
NR6A1 665
SALL4 130
SALL1 -3301
PBX1 -4675
POU5F1 -5000
EPAS1 -6040
NANOG -8002
ZSCAN10 -8306


REACTOME_ASPIRIN_ADME

REACTOME_ASPIRIN_ADME
1595
set REACTOME_ASPIRIN_ADME
setSize 42
pANOVA 0.009
s.dist -0.233
p.adjustANOVA 0.38



Top enriched genes

Top 20 genes
GeneID Gene Rank
ACSM4 -10217
SLC22A7 -9711
UGT2B11 -9535
CYP2D6 -9361
UGT2A3 -9303
SLCO2B1 -8772
UGT2B15 -8754
CYP2E1 -8375
UGT2B4 -8119
GLYATL3 -7241
ALB -6375
UGT1A6 -6021
UGT1A5 -5766
UGT1A4 -5283
UGT1A9 -5008
UGT1A7 -4933
UGT1A3 -4783
ACSM5 -4679
SLC16A1 -4667
CYP3A4 -4038

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ACSM4 -10217
SLC22A7 -9711
UGT2B11 -9535
CYP2D6 -9361
UGT2A3 -9303
SLCO2B1 -8772
UGT2B15 -8754
CYP2E1 -8375
UGT2B4 -8119
GLYATL3 -7241
ALB -6375
UGT1A6 -6021
UGT1A5 -5766
UGT1A4 -5283
UGT1A9 -5008
UGT1A7 -4933
UGT1A3 -4783
ACSM5 -4679
SLC16A1 -4667
CYP3A4 -4038
BSG -3954
CYP2C19 -3644
UGT1A8 -3536
GLYATL1 -3130
ABCC3 -2986
GLYATL2 -2975
UGT2A2 -2102
BCHE -1903
CES2 -1319
UGT1A1 11
ACSM2B 692
GLYAT 998
UGT2A1 1285
UGT3A1 1956
CYP2C9 4380
ABCC2 4864
UGT2B17 5385
CYP2C8 5755
CES1 9537
UGT3A2 9945
UGT2B7 10432
ACSM2A 10703


REACTOME_APOPTOSIS

REACTOME_APOPTOSIS
2
set REACTOME_APOPTOSIS
setSize 173
pANOVA 0.00913
s.dist 0.115
p.adjustANOVA 0.38



Top enriched genes

Top 20 genes
GeneID Gene Rank
SFN 11067
GSN 10627
TNFRSF10B 10045
PSMA1 10043
CD14 9901
APIP 9758
ACIN1 9702
PSMA6 9587
PSMB10 9558
PRKCD 9555
UBC 9309
YWHAG 9119
DFFA 9078
PSMD13 8956
UACA 8912
DBNL 8749
TRADD 8562
OCLN 8553
ADD1 8465
CARD8 8410

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SFN 11067
GSN 10627
TNFRSF10B 10045
PSMA1 10043
CD14 9901
APIP 9758
ACIN1 9702
PSMA6 9587
PSMB10 9558
PRKCD 9555
UBC 9309
YWHAG 9119
DFFA 9078
PSMD13 8956
UACA 8912
DBNL 8749
TRADD 8562
OCLN 8553
ADD1 8465
CARD8 8410
H1-3 8345
CASP6 8201
PSMB7 8153
DSG2 7765
TLR4 7476
YWHAZ 7406
BMF 7370
DAPK2 7312
PPP3R1 7266
CDKN2A 7234
BBC3 7198
DSG1 7175
H1-4 7174
UBB 6789
TP53BP2 6552
CASP7 6472
PSMB4 6341
DSG3 6312
CASP8 6261
APPL1 6224
SATB1 6212
LMNB1 6057
HMGB1 5972
PSMD12 5712
PSMD3 5632
LMNA 5585
PSME3 5531
PSMB1 5505
PSMA3 5324
TICAM2 5257
PSMC1 5255
PSMA2 5121
STAT3 5078
PSMC3 4952
DIABLO 4929
FADD 4876
BCL2L11 4581
BAD 4509
PSMC4 4459
BCL2 4375
OMA1 4346
DCC 4163
H1-1 4131
HMGB2 4061
DYNLL1 4014
PSMA7 3991
KPNB1 3909
PSMD14 3675
H1-2 3500
DFFB 3148
ARHGAP10 3124
TFDP2 3041
PTK2 2838
TICAM1 2667
PSMC5 2665
PMAIP1 2645
CFLAR 2213
UBA52 2012
TNFSF10 1915
H1-0 1896
TNFRSF10A 1837
PSME4 1702
DNM1L 1630
PSME2 1571
VIM 1515
AKT3 1256
MAPK8 1248
PPP3CC 1186
ROCK1 906
YWHAB 890
BAK1 667
PSMD7 646
PSMD6 620
PSMB3 544
SEM1 292
CDH1 279
BIRC2 154
TP73 82
YWHAE -5
PSMC6 -296
MAPK1 -343
PSMA4 -401
OPA1 -415
PSMD11 -439
DYNLL2 -462
PSMD2 -547
YWHAH -558
PSMB2 -611
PSMA8 -621
TP63 -648
AVEN -656
PSMD5 -828
PSMF1 -878
PPP1R13B -913
BCL2L1 -922
GSDMD -963
UNC5B -1033
PSMB8 -1223
MAPT -1418
APC -1581
PSMD4 -1623
BID -1669
PSMA5 -1800
CTNNB1 -1892
PSMD9 -2254
E2F1 -2318
PRKCQ -2320
GSDME -2390
UNC5A -2399
YWHAQ -2486
PSMB5 -2516
APAF1 -2526
FNTA -2544
TJP2 -2573
NMT1 -2584
SEPTIN4 -2637
PLEC -2834
CASP3 -2880
LY96 -3154
TP53 -3217
CLSPN -3446
CYCS -3692
FAS -3797
PSMB9 -3852
GAS2 -3870
KPNA1 -4042
CASP9 -4145
PSMC2 -4425
GZMB -4445
TFDP1 -4875
TJP1 -5048
DSP -5072
PSMD1 -5434
AKT1 -5452
FASLG -5977
PSME1 -5997
PSMB6 -6154
RPS27A -6304
PKP1 -6481
H1-5 -6844
AKT2 -7272
MAPK3 -7281
PSMD8 -7295
DAPK1 -7413
BAX -7528
PAK2 -7745
SPTAN1 -7825
STK24 -7984
TRAF2 -8333
DAPK3 -8881
C1QBP -9678
PSMB11 -10167
RIPK1 -10392


REACTOME_PYRIMIDINE_SALVAGE

REACTOME_PYRIMIDINE_SALVAGE
1154
set REACTOME_PYRIMIDINE_SALVAGE
setSize 10
pANOVA 0.0094
s.dist 0.474
p.adjustANOVA 0.38



Top enriched genes

Top 20 genes
GeneID Gene Rank
CDA 9563
TK2 9190
UPP1 8366
DCK 7892
UCK2 7729
TYMP 7539
TK1 4335
UPP2 2071
UCK1 -194
UCKL1 -2691

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CDA 9563
TK2 9190
UPP1 8366
DCK 7892
UCK2 7729
TYMP 7539
TK1 4335
UPP2 2071
UCK1 -194
UCKL1 -2691


REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS
658
set REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS
setSize 66
pANOVA 0.00949
s.dist -0.185
p.adjustANOVA 0.38



Top enriched genes

Top 20 genes
GeneID Gene Rank
B4GAT1 -10626
MUC20 -9134
ADAMTS14 -8822
ADAMTS2 -8610
MUC5B -8437
DAG1 -8390
POMT1 -8171
LARGE1 -8013
ADAMTS13 -7942
MUC16 -7920
MUC3A -7631
MUCL1 -7539
ADAMTS15 -7514
MUC6 -7403
ADAMTSL2 -7343
MUC4 -7070
POMT2 -7064
THSD1 -6700
NOTCH4 -6575
ADAMTS7 -6397

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
B4GAT1 -10626
MUC20 -9134
ADAMTS14 -8822
ADAMTS2 -8610
MUC5B -8437
DAG1 -8390
POMT1 -8171
LARGE1 -8013
ADAMTS13 -7942
MUC16 -7920
MUC3A -7631
MUCL1 -7539
ADAMTS15 -7514
MUC6 -7403
ADAMTSL2 -7343
MUC4 -7070
POMT2 -7064
THSD1 -6700
NOTCH4 -6575
ADAMTS7 -6397
ADAMTSL4 -6266
MUC17 -6224
SSPOP -6175
THSD4 -5832
POMGNT1 -5326
ADAMTS16 -5047
SEMA5B -4754
THBS2 -4681
GALNT3 -4646
SBSPON -4423
ADAMTS17 -3278
B3GLCT -3104
SEMA5A -3075
ADAMTSL1 -2830
MUC21 -2666
MUC13 -2398
NOTCH1 -1962
THBS1 -1782
ADAMTS3 -1738
NOTCH3 -1166
THSD7B -873
SPON1 23
ADAMTS10 875
THSD7A 1128
GALNT12 1720
ADAMTS12 1863
ADAMTS8 2163
ADAMTSL3 2540
ADAMTS6 2794
ADAMTS18 2801
ADAMTS1 2922
ADAMTS9 2931
MUC7 3634
ADAMTS5 3878
MUC15 3889
MUC1 4610
MUC5AC 4687
ADAMTS19 4719
C1GALT1 5558
ADAMTS4 5667
LFNG 6902
NOTCH2 8539
MUC12 8845
ADAMTSL5 9786
ADAMTS20 9860
SPON2 10377


REACTOME_DAP12_INTERACTIONS

REACTOME_DAP12_INTERACTIONS
464
set REACTOME_DAP12_INTERACTIONS
setSize 37
pANOVA 0.00989
s.dist 0.245
p.adjustANOVA 0.387



Top enriched genes

Top 20 genes
GeneID Gene Rank
TYROBP 11155
CD300LB 10951
NRAS 10599
SIGLEC15 10442
GRB2 10092
CD300E 9996
PIK3R2 9942
SHC1 9449
LCK 8208
NCR2 8134
TREM1 7960
SIRPB1 7698
B2M 6729
GRAP2 6657
KRAS 6597
VAV3 5601
HLA-B 5425
CLEC5A 4369
PIK3R1 3783
SOS1 3727

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TYROBP 11155
CD300LB 10951
NRAS 10599
SIGLEC15 10442
GRB2 10092
CD300E 9996
PIK3R2 9942
SHC1 9449
LCK 8208
NCR2 8134
TREM1 7960
SIRPB1 7698
B2M 6729
GRAP2 6657
KRAS 6597
VAV3 5601
HLA-B 5425
CLEC5A 4369
PIK3R1 3783
SOS1 3727
KLRD1 3186
SYK 2502
TREM2 510
LCP2 466
PIK3CB 107
SIGLEC14 -59
PIK3CA -1136
RAC1 -2468
HLA-C -3246
KLRK1 -4098
FYN -4809
PLCG1 -4968
PLCG2 -5512
HLA-E -6426
HRAS -7398
VAV2 -8143
LAT -10354


REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES
1448
set REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES
setSize 51
pANOVA 0.0102
s.dist -0.208
p.adjustANOVA 0.39



Top enriched genes

Top 20 genes
GeneID Gene Rank
FXYD4 -10680
CAMK2A -9831
FXYD3 -9775
ATP1A2 -9675
PLN -9657
ATP13A4 -9184
ATP9A -8974
ATP11A -8849
ATP13A5 -8825
ATP4B -8332
ATP2A2 -7639
ATP13A1 -7015
ATP8B1 -6535
ATP10B -6507
ATP10A -6440
ATP2B2 -6208
ATP2C2 -6185
ATP1B3 -5897
ATP12A -5882
ATP13A2 -5594

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FXYD4 -10680
CAMK2A -9831
FXYD3 -9775
ATP1A2 -9675
PLN -9657
ATP13A4 -9184
ATP9A -8974
ATP11A -8849
ATP13A5 -8825
ATP4B -8332
ATP2A2 -7639
ATP13A1 -7015
ATP8B1 -6535
ATP10B -6507
ATP10A -6440
ATP2B2 -6208
ATP2C2 -6185
ATP1B3 -5897
ATP12A -5882
ATP13A2 -5594
ATP1A3 -5447
CAMK2B -5445
ATP8A1 -5380
ATP2B4 -4977
ATP9B -4711
ATP2A3 -4340
ATP7B -3365
ATP11B -3354
ATP2B1 -2961
ATP1B2 -2649
CUTC -2613
ATP4A -2583
ATP1A4 -1641
ATP2A1 -2
ATP2C1 767
ATP1A1 1485
ATP8B2 2008
ATP8B4 3253
CALM1 4775
SRI 4858
ATP1B1 5883
ATP8A2 6058
SLN 6296
CAMK2D 6412
FXYD6 6631
ATP10D 6733
FXYD2 7282
ATP8B3 7913
CAMK2G 8634
FXYD7 9919
FXYD1 10203


REACTOME_SIGNALING_BY_MEMBRANE_TETHERED_FUSIONS_OF_PDGFRA_OR_PDGFRB

REACTOME_SIGNALING_BY_MEMBRANE_TETHERED_FUSIONS_OF_PDGFRA_OR_PDGFRB
1534
set REACTOME_SIGNALING_BY_MEMBRANE_TETHERED_FUSIONS_OF_PDGFRA_OR_PDGFRB
setSize 5
pANOVA 0.0111
s.dist 0.656
p.adjustANOVA 0.407



Top enriched genes

Top 20 genes
GeneID Gene Rank
BIN2 10824
ETV6 10692
KDR 6011
GOLGA4 5615
KANK1 3754

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
BIN2 10824
ETV6 10692
KDR 6011
GOLGA4 5615
KANK1 3754


REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING

REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING
375
set REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING
setSize 67
pANOVA 0.0113
s.dist 0.179
p.adjustANOVA 0.407



Top enriched genes

Top 20 genes
GeneID Gene Rank
CTSZ 10153
CPD 9816
FTL 9804
SNAP23 9013
TGOLN2 8298
AP3S1 8240
DNM2 7734
CLTB 7651
GNS 7615
BLOC1S6 7543
VAMP8 7442
SORT1 7362
BLOC1S4 6919
ARF1 6868
NAPA 6768
DNAJC6 6761
AP1M2 6574
RAB5C 6560
TFRC 5769
AP4S1 5574

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CTSZ 10153
CPD 9816
FTL 9804
SNAP23 9013
TGOLN2 8298
AP3S1 8240
DNM2 7734
CLTB 7651
GNS 7615
BLOC1S6 7543
VAMP8 7442
SORT1 7362
BLOC1S4 6919
ARF1 6868
NAPA 6768
DNAJC6 6761
AP1M2 6574
RAB5C 6560
TFRC 5769
AP4S1 5574
PIK3C2A 5497
CLVS2 5451
CLTA 5191
CLTC 5063
BLOC1S3 4996
DTNBP1 4980
DNASE2 4759
PICALM 4358
SNX9 4226
AP4E1 4184
AP4B1 3967
TXNDC5 3666
FTH1 3639
HSPA8 3085
AP1S3 3074
ARRB1 2678
TPD52 2511
APP 1659
BLOC1S1 1621
ACBD3 1471
PUM1 986
SNX5 946
AP1G1 804
GBF1 271
CLVS1 -75
AP1G2 -447
SH3GL2 -637
AP1B1 -1093
CHMP2A -1412
AP3B1 -1735
AP1M1 -2047
AP4M1 -2371
IGF2R -2886
TPD52L1 -2890
M6PR -2925
SH3D19 -3740
CLINT1 -3759
NECAP1 -3945
AP1S1 -4080
SNX2 -4154
VAMP2 -5341
STX4 -5486
SNAPIN -6562
GOLGB1 -7177
HIP1R -8244
HGS -8902
GAK -9065


REACTOME_SODIUM_COUPLED_SULPHATE_DI_AND_TRI_CARBOXYLATE_TRANSPORTERS

REACTOME_SODIUM_COUPLED_SULPHATE_DI_AND_TRI_CARBOXYLATE_TRANSPORTERS
758
set REACTOME_SODIUM_COUPLED_SULPHATE_DI_AND_TRI_CARBOXYLATE_TRANSPORTERS
setSize 5
pANOVA 0.0116
s.dist -0.652
p.adjustANOVA 0.407



Top enriched genes

Top 20 genes
GeneID Gene Rank
SLC13A2 -10214
SLC13A4 -10090
SLC13A5 -8662
SLC13A1 -3824
SLC13A3 -2251

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SLC13A2 -10214
SLC13A4 -10090
SLC13A5 -8662
SLC13A1 -3824
SLC13A3 -2251


REACTOME_UNFOLDED_PROTEIN_RESPONSE_UPR

REACTOME_UNFOLDED_PROTEIN_RESPONSE_UPR
623
set REACTOME_UNFOLDED_PROTEIN_RESPONSE_UPR
setSize 88
pANOVA 0.0117
s.dist 0.156
p.adjustANOVA 0.407



Top enriched genes

Top 20 genes
GeneID Gene Rank
ERN1 10538
PREB 10489
DDIT3 10329
ATF4 10029
CCL2 10003
CALR 9928
CREB3L4 9787
CREB3L3 9775
HSP90B1 9489
SHC1 9449
XBP1 9400
CREB3 8916
MYDGF 8590
ADD1 8465
HSPA5 8402
CREB3L2 8336
CTDSP2 8300
ASNS 8236
IGFBP1 7413
EIF2S1 7331

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ERN1 10538
PREB 10489
DDIT3 10329
ATF4 10029
CCL2 10003
CALR 9928
CREB3L4 9787
CREB3L3 9775
HSP90B1 9489
SHC1 9449
XBP1 9400
CREB3 8916
MYDGF 8590
ADD1 8465
HSPA5 8402
CREB3L2 8336
CTDSP2 8300
ASNS 8236
IGFBP1 7413
EIF2S1 7331
DIS3 6935
SYVN1 6863
WIPI1 6817
PPP2R5B 5914
LMNA 5585
DCP2 5583
FKBP14 5470
DNAJC3 5445
KLHDC3 5343
DCTN1 5314
EDEM1 5166
CREB3L1 5028
EXOSC7 4999
YIF1A 4917
NFYB 4893
GOSR2 4150
EXOSC9 3893
MBTPS1 3845
DNAJB11 3573
DDX11 2799
ZBTB17 2741
EXTL2 2581
EIF2AK3 2332
ACADVL 2024
SERP1 2016
KHSRP 1779
EXTL1 1651
TLN1 1585
TPP1 1452
ATF3 1301
SSR1 984
PARN 674
EXOSC4 586
HDGF 508
ATF6 75
EIF2S2 20
CEBPG -195
EXOSC5 -224
CXCL8 -272
NFYC -782
NFYA -1006
TATDN2 -1347
EXTL3 -1795
PDIA6 -1848
EXOSC3 -2512
SRPRB -2697
ARFGAP1 -2829
HERPUD1 -2943
ATP6V0D1 -3765
SEC31A -3800
GFPT1 -3828
CXXC1 -4210
GSK3A -4733
EXOSC8 -5087
EXOSC6 -5221
EXOSC2 -5329
SRPRA -6353
DCSTAMP -6410
CEBPB -6536
KDELR3 -6882
PDIA5 -6923
EXOSC1 -6949
CREBRF -7302
DNAJB9 -7488
WFS1 -7757
PLA2G4B -8652
HYOU1 -8913
CUL7 -9037


REACTOME_ANTIMICROBIAL_PEPTIDES

REACTOME_ANTIMICROBIAL_PEPTIDES
1060
set REACTOME_ANTIMICROBIAL_PEPTIDES
setSize 76
pANOVA 0.012
s.dist 0.167
p.adjustANOVA 0.407



Top enriched genes

Top 20 genes
GeneID Gene Rank
S100A8 11160
RNASE3 11070
DEFA4 11054
PRTN3 11038
CTSG 11021
ELANE 10883
S100A9 10770
PGLYRP1 10757
DEFB1 10678
DEFB133 10625
PGLYRP2 10602
DEFA6 10584
RNASE7 10422
SLC11A1 10399
LCN2 10211
CLU 10138
ITLN1 10010
REG3A 10009
DEFB124 9967
LYZ 9574

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
S100A8 11160.0
RNASE3 11070.0
DEFA4 11054.0
PRTN3 11038.0
CTSG 11021.0
ELANE 10883.0
S100A9 10770.0
PGLYRP1 10757.0
DEFB1 10678.0
DEFB133 10625.0
PGLYRP2 10602.0
DEFA6 10584.0
RNASE7 10422.0
SLC11A1 10399.0
LCN2 10211.0
CLU 10138.0
ITLN1 10010.0
REG3A 10009.0
DEFB124 9967.0
LYZ 9574.0
DEFB110 9243.0
CCR2 9002.0
HTN1 8848.0
PGLYRP4 8679.0
DEFB116 8532.0
CAMP 8195.0
CHGA 8189.0
DEFB118 7560.0
TLR1 7139.0
DEFB126 6443.0
S100A7A 6233.0
LTF 5848.0
TLR2 5534.0
DEFB121 4540.0
RNASE6 3743.0
DEFB104A 3584.5
DEFB104B 3584.5
DEFB127 3172.0
BPIFA1 2904.0
ATOX1 1811.0
LEAP2 1125.0
DEFB125 1068.0
DCD 840.0
DEFA5 818.0
PI3 735.0
BPIFB1 -733.0
DEFB119 -2123.0
GNLY -2605.0
DEFB123 -2728.0
DEFB113 -2906.0
DEFB128 -3197.0
RNASE8 -3525.0
REG3G -3553.0
ART1 -3802.0
DEFB115 -4109.0
BPIFB4 -5060.0
EPPIN-WFDC6 -5311.0
BPI -5428.0
SEMG1 -5554.0
BPIFB2 -5857.0
DEFB132 -5873.0
EPPIN -6230.0
PLA2G2A -6567.0
PGLYRP3 -6988.0
CD4 -7557.0
DEFB134 -7656.0
HTN3 -7851.0
DEFB136 -8021.0
PRSS3 -8389.0
DEFB114 -8771.0
S100A7 -9091.0
DEFB135 -9097.0
CCR6 -9111.0
DEFB129 -9133.0
BPIFA2 -9576.0
BPIFB6 -10539.0


REACTOME_REGULATION_OF_RUNX2_EXPRESSION_AND_ACTIVITY

REACTOME_REGULATION_OF_RUNX2_EXPRESSION_AND_ACTIVITY
1289
set REACTOME_REGULATION_OF_RUNX2_EXPRESSION_AND_ACTIVITY
setSize 72
pANOVA 0.0123
s.dist 0.171
p.adjustANOVA 0.407



Top enriched genes

Top 20 genes
GeneID Gene Rank
PSMA1 10043
RBX1 9765
PSMA6 9587
PSMB10 9558
UBC 9309
PSMD13 8956
PSMB7 8153
BMP2 7789
NKX3-2 7348
UBB 6789
PSMB4 6341
CUL1 6104
SKP2 6091
DLX5 6014
GSK3B 5966
PSMD12 5712
TWIST1 5681
DLX6 5675
PPARGC1B 5659
PSMD3 5632

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PSMA1 10043
RBX1 9765
PSMA6 9587
PSMB10 9558
UBC 9309
PSMD13 8956
PSMB7 8153
BMP2 7789
NKX3-2 7348
UBB 6789
PSMB4 6341
CUL1 6104
SKP2 6091
DLX5 6014
GSK3B 5966
PSMD12 5712
TWIST1 5681
DLX6 5675
PPARGC1B 5659
PSMD3 5632
PSME3 5531
PSMB1 5505
PSMA3 5324
PSMC1 5255
PSMA2 5121
PSMC3 4952
HIVEP3 4879
PSMC4 4459
PPARGC1A 4072
SMURF1 4010
PSMA7 3991
PSMD14 3675
RUNX2 2802
PSMC5 2665
MSX2 2402
STUB1 2116
UBA52 2012
PSME4 1702
FBXW7 1587
PSME2 1571
NR3C1 760
PSMD7 646
PSMD6 620
PSMB3 544
SEM1 292
SKP1 51
PSMC6 -296
PSMA4 -401
PSMD11 -439
PSMD2 -547
PSMB2 -611
PSMA8 -621
ESRRA -715
PSMD5 -828
PSMF1 -878
PSMB8 -1223
ESR1 -1245
STAT1 -1367
PSMD4 -1623
PSMA5 -1800
PSMD9 -2254
PSMB5 -2516
PSMB9 -3852
CBFB -4226
PSMC2 -4425
WWP1 -4980
PSMD1 -5434
PSME1 -5997
PSMB6 -6154
RPS27A -6304
PSMD8 -7295
PSMB11 -10167


REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL

REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL
369
set REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL
setSize 122
pANOVA 0.0124
s.dist 0.131
p.adjustANOVA 0.407



Top enriched genes

Top 20 genes
GeneID Gene Rank
TYROBP 11155
LILRB2 10980
CD300LB 10951
PILRA 10885
PILRB 10863
KIR2DL4 10780
SIGLEC10 10597
SLAMF7 10528
SIGLEC8 10460
CD33 10455
SLAMF6 10429
OSCAR 10403
LILRA4 10337
HCST 10266
CD300E 9996
ICAM5 9814
LAIR1 9772
FCGR3A 9561
SIGLEC7 9560
KIR2DL1 9424

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TYROBP 11155
LILRB2 10980
CD300LB 10951
PILRA 10885
PILRB 10863
KIR2DL4 10780
SIGLEC10 10597
SLAMF7 10528
SIGLEC8 10460
CD33 10455
SLAMF6 10429
OSCAR 10403
LILRA4 10337
HCST 10266
CD300E 9996
ICAM5 9814
LAIR1 9772
FCGR3A 9561
SIGLEC7 9560
KIR2DL1 9424
ICAM3 9384
CD22 9094
ULBP3 8992
TREML1 8967
NECTIN2 8963
JAML 8826
SIGLEC6 8819
TREML2 8779
CRTAM 8705
CD40 8697
CD300LG 8589
SIGLEC9 8524
ITGB7 8179
LILRA2 8155
NCR2 8134
TREM1 7960
IFITM1 7620
CD160 7558
KLRF1 7550
KIR3DL2 7508
KLRB1 7306
CLEC2B 7270
KLRG1 6886
B2M 6729
CLEC4G 6539
ICAM2 6330
CD3E 5636
SIGLEC12 5498
HLA-B 5425
CLEC2D 5266
LILRA3 5071
PIANP 5015
CD200R1 4491
TREML4 4316
CD300LF 3798
ICAM1 3541
ICAM4 3430
KLRD1 3186
CD34 3009
NCR1 2528
ITGA4 2339
NPDC1 2308
MADCAM1 2304
HLA-G 1735
ITGAL 1490
CXADR 776
CD300LD 547
TREM2 510
CDH1 279
COL1A1 -337
CD200 -895
CD96 -1164
RAET1E -1417
CD1B -1564
PVR -1662
COLEC12 -1775
SFTPD -1871
NCR3LG1 -2238
COL3A1 -2263
CD1A -2447
COL2A1 -2800
HLA-C -3246
CD1D -3307
CD247 -3369
HLA-A -3534
ITGB2 -3578
SELL -3771
MICA -3884
CD300A -4090
LAIR2 -4096
KLRK1 -4098
COL17A1 -4260
CD8A -4282
ULBP1 -4494
NCR3 -4578
CD19 -5138
MICB -5390
CD1C -5459
VCAM1 -5924
HLA-F -6405
HLA-E -6426
KLRC1 -6969
ITGB1 -7226
SIGLEC11 -7274
SH2D1B -7424
COL1A2 -7661
LILRB3 -7758
LILRB5 -8052
LILRB1 -8056
SIGLEC5 -8565
C3 -8607
CD226 -8766
CD81 -8770
CD300C -8773
LILRA5 -9315
CD3G -9602
KIR3DL1 -9936
LILRB4 -10053
CD3D -10492
SIGLEC1 -10496
LILRA1 -10570
CD8B -10657


Here is the session info with all the versions of packages used.

sessionInfo()
## R version 4.3.2 (2023-10-31)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.3 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3 
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so;  LAPACK version 3.10.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Etc/UTC
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.3.3                                      
##  [2] GGally_2.2.0                                       
##  [3] ggplot2_3.4.4                                      
##  [4] reshape2_1.4.4                                     
##  [5] gtools_3.9.5                                       
##  [6] tibble_3.2.1                                       
##  [7] dplyr_1.1.4                                        
##  [8] echarts4r_0.4.5                                    
##  [9] png_0.1-8                                          
## [10] gridExtra_2.3                                      
## [11] missMethyl_1.36.0                                  
## [12] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.1 
## [13] beeswarm_0.4.0                                     
## [14] kableExtra_1.3.4                                   
## [15] gplots_3.1.3                                       
## [16] mitch_1.15.0                                       
## [17] tictoc_1.2                                         
## [18] HGNChelper_0.8.1                                   
## [19] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [20] IlluminaHumanMethylation450kmanifest_0.4.0         
## [21] minfi_1.48.0                                       
## [22] bumphunter_1.44.0                                  
## [23] locfit_1.5-9.8                                     
## [24] iterators_1.0.14                                   
## [25] foreach_1.5.2                                      
## [26] Biostrings_2.70.1                                  
## [27] XVector_0.42.0                                     
## [28] SummarizedExperiment_1.32.0                        
## [29] Biobase_2.62.0                                     
## [30] MatrixGenerics_1.14.0                              
## [31] matrixStats_1.2.0                                  
## [32] GenomicRanges_1.54.1                               
## [33] GenomeInfoDb_1.38.2                                
## [34] IRanges_2.36.0                                     
## [35] S4Vectors_0.40.2                                   
## [36] BiocGenerics_0.48.1                                
## [37] eulerr_7.0.0                                       
## [38] limma_3.58.1                                       
## 
## loaded via a namespace (and not attached):
##   [1] splines_4.3.2             later_1.3.2              
##   [3] BiocIO_1.12.0             bitops_1.0-7             
##   [5] filelock_1.0.3            preprocessCore_1.64.0    
##   [7] XML_3.99-0.16             lifecycle_1.0.4          
##   [9] lattice_0.22-5            MASS_7.3-60              
##  [11] base64_2.0.1              scrime_1.3.5             
##  [13] magrittr_2.0.3            sass_0.4.8               
##  [15] rmarkdown_2.25            jquerylib_0.1.4          
##  [17] yaml_2.3.8                httpuv_1.6.13            
##  [19] doRNG_1.8.6               askpass_1.2.0            
##  [21] DBI_1.1.3                 RColorBrewer_1.1-3       
##  [23] abind_1.4-5               zlibbioc_1.48.0          
##  [25] rvest_1.0.3               quadprog_1.5-8           
##  [27] purrr_1.0.2               RCurl_1.98-1.13          
##  [29] rappdirs_0.3.3            GenomeInfoDbData_1.2.11  
##  [31] genefilter_1.84.0         annotate_1.80.0          
##  [33] svglite_2.1.3             DelayedMatrixStats_1.24.0
##  [35] codetools_0.2-19          DelayedArray_0.28.0      
##  [37] xml2_1.3.6                tidyselect_1.2.0         
##  [39] beanplot_1.3.1            BiocFileCache_2.10.1     
##  [41] webshot_0.5.5             illuminaio_0.44.0        
##  [43] GenomicAlignments_1.38.0  jsonlite_1.8.8           
##  [45] multtest_2.58.0           ellipsis_0.3.2           
##  [47] survival_3.5-7            systemfonts_1.0.5        
##  [49] tools_4.3.2               progress_1.2.3           
##  [51] Rcpp_1.0.11               glue_1.6.2               
##  [53] SparseArray_1.2.2         xfun_0.41                
##  [55] HDF5Array_1.30.0          withr_2.5.2              
##  [57] fastmap_1.1.1             rhdf5filters_1.14.1      
##  [59] fansi_1.0.6               openssl_2.1.1            
##  [61] caTools_1.18.2            digest_0.6.33            
##  [63] R6_2.5.1                  mime_0.12                
##  [65] colorspace_2.1-0          biomaRt_2.58.0           
##  [67] RSQLite_2.3.4             utf8_1.2.4               
##  [69] tidyr_1.3.0               generics_0.1.3           
##  [71] data.table_1.14.10        rtracklayer_1.62.0       
##  [73] prettyunits_1.2.0         httr_1.4.7               
##  [75] htmlwidgets_1.6.4         S4Arrays_1.2.0           
##  [77] ggstats_0.5.1             pkgconfig_2.0.3          
##  [79] gtable_0.3.4              blob_1.2.4               
##  [81] siggenes_1.76.0           htmltools_0.5.7          
##  [83] scales_1.3.0              rstudioapi_0.15.0        
##  [85] knitr_1.45                tzdb_0.4.0               
##  [87] rjson_0.2.21              nlme_3.1-163             
##  [89] curl_5.2.0                org.Hs.eg.db_3.18.0      
##  [91] cachem_1.0.8              rhdf5_2.46.1             
##  [93] stringr_1.5.1             KernSmooth_2.23-22       
##  [95] AnnotationDbi_1.64.1      restfulr_0.0.15          
##  [97] GEOquery_2.70.0           pillar_1.9.0             
##  [99] grid_4.3.2                reshape_0.8.9            
## [101] vctrs_0.6.5               promises_1.2.1           
## [103] dbplyr_2.4.0              xtable_1.8-4             
## [105] evaluate_0.23             readr_2.1.4              
## [107] GenomicFeatures_1.54.1    cli_3.6.2                
## [109] compiler_4.3.2            Rsamtools_2.18.0         
## [111] rlang_1.1.2               crayon_1.5.2             
## [113] rngtools_1.5.2            nor1mix_1.3-2            
## [115] mclust_6.0.1              plyr_1.8.9               
## [117] stringi_1.8.3             viridisLite_0.4.2        
## [119] BiocParallel_1.36.0       munsell_0.5.0            
## [121] Matrix_1.6-1.1            hms_1.1.3                
## [123] sparseMatrixStats_1.14.0  bit64_4.0.5              
## [125] Rhdf5lib_1.24.1           KEGGREST_1.42.0          
## [127] statmod_1.5.0             shiny_1.8.0              
## [129] highr_0.10                memoise_2.0.1            
## [131] bslib_0.6.1               bit_4.0.5

END of report