Mitch Report

date generated: 2024-01-18

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch

	x
A1BG	0.0057866
A1BG-AS1	0.0081335
A1CF	-0.0011424
A2M	0.0053740
A2M-AS1	0.0134360
A2ML1	0.0024537

Here are some metrics about the input data profile:

Profiling data metrics

	Profile metrics
num_genesets	1654
num_genes_in_profile	22007
duplicated_genes_present	0
num_profile_genes_in_sets	10383
num_profile_genes_not_in_sets	11624

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets: c2.cp.reactome.v2023.1.Hs.symbols.gmt

Gene set metrics

	Gene sets metrics
num_genesets	1654
num_genesets_excluded	365
num_genesets_included	1289

Differential pathway expression

Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

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## in kable. kableExtra can customize either HTML or LaTeX outputs. See
## https://haozhu233.github.io/kableExtra/ for details.

set	setSize	pANOVA	s.dist	p.adjustANOVA
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	105	7.36e-08	-0.3040	4.37e-05
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS	161	7.36e-08	-0.2460	4.37e-05
REACTOME EUKARYOTIC TRANSLATION INITIATION	110	7.99e-08	-0.2960	4.37e-05
REACTOME EUKARYOTIC TRANSLATION ELONGATION	87	1.44e-07	-0.3260	5.01e-05
REACTOME NONSENSE MEDIATED DECAY NMD	107	1.53e-07	-0.2940	5.01e-05
REACTOME METABOLISM OF RNA	675	2.69e-07	-0.1160	7.36e-05
REACTOME INFLUENZA INFECTION	149	4.49e-07	-0.2390	1.05e-04
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY	94	7.03e-07	-0.2960	1.44e-04
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM	688	1.23e-06	-0.1080	2.23e-04
REACTOME SIGNALING BY INTERLEUKINS	444	1.36e-06	-0.1340	2.23e-04
REACTOME TRANSLATION	278	1.91e-06	-0.1660	2.85e-04
REACTOME INTERLEUKIN 10 SIGNALING	43	2.42e-06	-0.4150	3.30e-04
REACTOME SENSORY PERCEPTION	555	6.41e-06	0.1120	8.10e-04
REACTOME SELENOAMINO ACID METABOLISM	108	1.26e-05	-0.2430	1.48e-03
REACTOME DEVELOPMENTAL BIOLOGY	1115	3.15e-05	-0.0739	3.45e-03
REACTOME RRNA PROCESSING	192	3.42e-05	-0.1730	3.51e-03
REACTOME SIGNALING BY ROBO RECEPTORS	206	4.49e-05	-0.1650	4.34e-03
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	55	6.14e-05	-0.3120	5.60e-03
REACTOME CELLULAR RESPONSES TO STIMULI	779	9.23e-05	-0.0823	7.97e-03
REACTOME PEPTIDE LIGAND BINDING RECEPTORS	188	1.48e-04	-0.1600	1.22e-02
REACTOME MITOCHONDRIAL PROTEIN IMPORT	58	2.38e-04	-0.2790	1.86e-02
REACTOME NERVOUS SYSTEM DEVELOPMENT	552	1.03e-03	-0.0817	7.00e-02
REACTOME SARS COV 1 HOST INTERACTIONS	92	1.07e-03	-0.1970	7.00e-02
REACTOME EXTRACELLULAR MATRIX ORGANIZATION	291	1.12e-03	0.1110	7.00e-02
REACTOME CALCITONIN LIKE LIGAND RECEPTORS	10	1.12e-03	-0.5950	7.00e-02
REACTOME TNFR2 NON CANONICAL NF KB PATHWAY	96	1.15e-03	-0.1920	7.00e-02
REACTOME VISUAL PHOTOTRANSDUCTION	93	1.15e-03	0.1950	7.00e-02
REACTOME INNATE IMMUNE SYSTEM	1002	1.26e-03	-0.0602	7.08e-02
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS	121	1.28e-03	-0.1690	7.08e-02
REACTOME FASL CD95L SIGNALING	5	1.29e-03	-0.8310	7.08e-02
REACTOME INFECTIOUS DISEASE	910	1.47e-03	-0.0622	7.78e-02
REACTOME CELLULAR RESPONSE TO STARVATION	147	1.56e-03	-0.1510	8.03e-02
REACTOME COLLAGEN FORMATION	88	1.84e-03	0.1920	9.13e-02
REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS	418	1.91e-03	-0.0885	9.22e-02
REACTOME SARS COV 1 INFECTION	136	2.21e-03	-0.1520	1.04e-01
REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE	11	2.83e-03	0.5200	1.29e-01
REACTOME INTERLEUKIN 1 FAMILY SIGNALING	146	2.96e-03	-0.1420	1.32e-01
REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER	18	3.52e-03	-0.3970	1.47e-01
REACTOME NEUTROPHIL DEGRANULATION	460	3.57e-03	-0.0793	1.47e-01
REACTOME DNA REPLICATION	178	3.59e-03	-0.1270	1.47e-01
REACTOME RNA POLYMERASE II TRANSCRIPTION	1336	3.88e-03	-0.0471	1.55e-01
REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER	77	4.51e-03	-0.1870	1.76e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1	229	4.66e-03	-0.1090	1.76e-01
REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS	55	4.71e-03	0.2200	1.76e-01
REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING	45	4.98e-03	-0.2420	1.78e-01
REACTOME DAP12 SIGNALING	27	5.18e-03	-0.3110	1.78e-01
REACTOME SIGNALING BY EGFR IN CANCER	25	5.27e-03	-0.3220	1.78e-01
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY	33	5.32e-03	-0.2800	1.78e-01
REACTOME MEIOTIC RECOMBINATION	80	5.39e-03	-0.1800	1.78e-01
REACTOME INTERLEUKIN 2 SIGNALING	11	5.48e-03	-0.4840	1.78e-01

---

Results (complete table)

Click HERE to show results for all gene sets

Complete results

set	setSize	pANOVA	s.dist	p.adjustANOVA
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	105	7.36e-08	-3.04e-01	4.37e-05
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS	161	7.36e-08	-2.46e-01	4.37e-05
REACTOME EUKARYOTIC TRANSLATION INITIATION	110	7.99e-08	-2.96e-01	4.37e-05
REACTOME EUKARYOTIC TRANSLATION ELONGATION	87	1.44e-07	-3.26e-01	5.01e-05
REACTOME NONSENSE MEDIATED DECAY NMD	107	1.53e-07	-2.94e-01	5.01e-05
REACTOME METABOLISM OF RNA	675	2.69e-07	-1.16e-01	7.36e-05
REACTOME INFLUENZA INFECTION	149	4.49e-07	-2.39e-01	1.05e-04
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY	94	7.03e-07	-2.96e-01	1.44e-04
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM	688	1.23e-06	-1.08e-01	2.23e-04
REACTOME SIGNALING BY INTERLEUKINS	444	1.36e-06	-1.34e-01	2.23e-04
REACTOME TRANSLATION	278	1.91e-06	-1.66e-01	2.85e-04
REACTOME INTERLEUKIN 10 SIGNALING	43	2.42e-06	-4.15e-01	3.30e-04
REACTOME SENSORY PERCEPTION	555	6.41e-06	1.12e-01	8.10e-04
REACTOME SELENOAMINO ACID METABOLISM	108	1.26e-05	-2.43e-01	1.48e-03
REACTOME DEVELOPMENTAL BIOLOGY	1115	3.15e-05	-7.39e-02	3.45e-03
REACTOME RRNA PROCESSING	192	3.42e-05	-1.73e-01	3.51e-03
REACTOME SIGNALING BY ROBO RECEPTORS	206	4.49e-05	-1.65e-01	4.34e-03
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	55	6.14e-05	-3.12e-01	5.60e-03
REACTOME CELLULAR RESPONSES TO STIMULI	779	9.23e-05	-8.23e-02	7.97e-03
REACTOME PEPTIDE LIGAND BINDING RECEPTORS	188	1.48e-04	-1.60e-01	1.22e-02
REACTOME MITOCHONDRIAL PROTEIN IMPORT	58	2.38e-04	-2.79e-01	1.86e-02
REACTOME NERVOUS SYSTEM DEVELOPMENT	552	1.03e-03	-8.17e-02	7.00e-02
REACTOME SARS COV 1 HOST INTERACTIONS	92	1.07e-03	-1.97e-01	7.00e-02
REACTOME EXTRACELLULAR MATRIX ORGANIZATION	291	1.12e-03	1.11e-01	7.00e-02
REACTOME CALCITONIN LIKE LIGAND RECEPTORS	10	1.12e-03	-5.95e-01	7.00e-02
REACTOME TNFR2 NON CANONICAL NF KB PATHWAY	96	1.15e-03	-1.92e-01	7.00e-02
REACTOME VISUAL PHOTOTRANSDUCTION	93	1.15e-03	1.95e-01	7.00e-02
REACTOME INNATE IMMUNE SYSTEM	1002	1.26e-03	-6.02e-02	7.08e-02
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS	121	1.28e-03	-1.69e-01	7.08e-02
REACTOME FASL CD95L SIGNALING	5	1.29e-03	-8.31e-01	7.08e-02
REACTOME INFECTIOUS DISEASE	910	1.47e-03	-6.22e-02	7.78e-02
REACTOME CELLULAR RESPONSE TO STARVATION	147	1.56e-03	-1.51e-01	8.03e-02
REACTOME COLLAGEN FORMATION	88	1.84e-03	1.92e-01	9.13e-02
REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS	418	1.91e-03	-8.85e-02	9.22e-02
REACTOME SARS COV 1 INFECTION	136	2.21e-03	-1.52e-01	1.04e-01
REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE	11	2.83e-03	5.20e-01	1.29e-01
REACTOME INTERLEUKIN 1 FAMILY SIGNALING	146	2.96e-03	-1.42e-01	1.32e-01
REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER	18	3.52e-03	-3.97e-01	1.47e-01
REACTOME NEUTROPHIL DEGRANULATION	460	3.57e-03	-7.93e-02	1.47e-01
REACTOME DNA REPLICATION	178	3.59e-03	-1.27e-01	1.47e-01
REACTOME RNA POLYMERASE II TRANSCRIPTION	1336	3.88e-03	-4.71e-02	1.55e-01
REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER	77	4.51e-03	-1.87e-01	1.76e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1	229	4.66e-03	-1.09e-01	1.76e-01
REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS	55	4.71e-03	2.20e-01	1.76e-01
REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING	45	4.98e-03	-2.42e-01	1.78e-01
REACTOME DAP12 SIGNALING	27	5.18e-03	-3.11e-01	1.78e-01
REACTOME SIGNALING BY EGFR IN CANCER	25	5.27e-03	-3.22e-01	1.78e-01
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY	33	5.32e-03	-2.80e-01	1.78e-01
REACTOME MEIOTIC RECOMBINATION	80	5.39e-03	-1.80e-01	1.78e-01
REACTOME INTERLEUKIN 2 SIGNALING	11	5.48e-03	-4.84e-01	1.78e-01
REACTOME GAB1 SIGNALOSOME	17	5.74e-03	-3.87e-01	1.78e-01
REACTOME INTERLEUKIN 2 FAMILY SIGNALING	40	5.88e-03	-2.52e-01	1.78e-01
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	122	6.04e-03	-1.44e-01	1.78e-01
REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS	16	6.16e-03	-3.96e-01	1.78e-01
REACTOME ION CHANNEL TRANSPORT	172	6.16e-03	1.21e-01	1.78e-01
REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	93	6.18e-03	-1.64e-01	1.78e-01
REACTOME DIGESTION AND ABSORPTION	22	6.45e-03	3.35e-01	1.78e-01
REACTOME DEFECTIVE F9 ACTIVATION	5	6.56e-03	-7.02e-01	1.78e-01
REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	66	6.60e-03	-1.93e-01	1.78e-01
REACTOME SHC1 EVENTS IN EGFR SIGNALING	14	6.61e-03	-4.19e-01	1.78e-01
REACTOME EGFR DOWNREGULATION	30	6.70e-03	-2.86e-01	1.78e-01
REACTOME SIGNALING BY ERBB4	57	6.87e-03	-2.07e-01	1.78e-01
REACTOME PROTEIN LOCALIZATION	153	6.91e-03	-1.27e-01	1.78e-01
REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	39	7.03e-03	2.49e-01	1.78e-01
REACTOME OLFACTORY SIGNALING PATHWAY	348	7.06e-03	8.40e-02	1.78e-01
REACTOME FREE FATTY ACID RECEPTORS	5	7.23e-03	6.94e-01	1.78e-01
REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP	104	7.36e-03	-1.52e-01	1.78e-01
REACTOME GPCR LIGAND BINDING	444	7.37e-03	-7.42e-02	1.78e-01
REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING	34	7.68e-03	-2.64e-01	1.83e-01
REACTOME TYPE I HEMIDESMOSOME ASSEMBLY	11	7.98e-03	4.62e-01	1.84e-01
REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS	312	8.21e-03	-8.70e-02	1.84e-01
REACTOME DAP12 INTERACTIONS	37	8.27e-03	-2.51e-01	1.84e-01
REACTOME COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES	65	8.29e-03	1.89e-01	1.84e-01
REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	35	8.33e-03	-2.58e-01	1.84e-01
REACTOME DNA REPLICATION PRE INITIATION	150	8.52e-03	-1.24e-01	1.84e-01
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	53	8.61e-03	-2.09e-01	1.84e-01
REACTOME CELL CYCLE MITOTIC	539	8.65e-03	-6.61e-02	1.84e-01
REACTOME ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES	59	8.84e-03	1.97e-01	1.86e-01
REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	111	9.00e-03	-1.44e-01	1.87e-01
REACTOME INTERLEUKIN 1 SIGNALING	110	9.43e-03	-1.43e-01	1.92e-01
REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS	60	9.53e-03	-1.93e-01	1.92e-01
REACTOME SIGNALING BY NTRKS	132	9.60e-03	-1.31e-01	1.92e-01
REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS	8	1.08e-02	-5.20e-01	2.04e-01
REACTOME LIGAND RECEPTOR INTERACTIONS	8	1.10e-02	-5.19e-01	2.04e-01
REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	134	1.10e-02	1.27e-01	2.04e-01
REACTOME CALNEXIN CALRETICULIN CYCLE	26	1.10e-02	-2.88e-01	2.04e-01
REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION	100	1.11e-02	-1.47e-01	2.04e-01
REACTOME TRAIL SIGNALING	8	1.11e-02	-5.18e-01	2.04e-01
REACTOME DNA DAMAGE REVERSAL	8	1.14e-02	5.17e-01	2.04e-01
REACTOME INTERLEUKIN 21 SIGNALING	9	1.14e-02	-4.87e-01	2.04e-01
REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION	10	1.14e-02	-4.62e-01	2.04e-01
REACTOME DEUBIQUITINATION	260	1.17e-02	-9.08e-02	2.04e-01
REACTOME SIGNALING BY PTK6	54	1.17e-02	-1.98e-01	2.04e-01
REACTOME DEFECTIVE LFNG CAUSES SCDO3	5	1.18e-02	6.50e-01	2.04e-01
REACTOME REGULATED NECROSIS	57	1.18e-02	-1.93e-01	2.04e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION	89	1.20e-02	-1.54e-01	2.04e-01
REACTOME PI3K EVENTS IN ERBB4 SIGNALING	10	1.21e-02	-4.58e-01	2.05e-01
REACTOME CYCLIN D ASSOCIATED EVENTS IN G1	46	1.23e-02	-2.13e-01	2.06e-01
REACTOME ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION	16	1.29e-02	-3.59e-01	2.14e-01
REACTOME PLASMA LIPOPROTEIN REMODELING	33	1.31e-02	2.50e-01	2.15e-01
REACTOME REGULATION OF SIGNALING BY CBL	22	1.37e-02	-3.03e-01	2.18e-01
REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY	46	1.38e-02	-2.10e-01	2.18e-01
REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21	59	1.38e-02	-1.85e-01	2.18e-01
REACTOME SIGNALING BY CSF3 G CSF	30	1.40e-02	-2.59e-01	2.18e-01
REACTOME SIGNALING BY FGFR2	72	1.41e-02	-1.67e-01	2.18e-01
REACTOME ADAPTIVE IMMUNE SYSTEM	729	1.43e-02	-5.33e-02	2.18e-01
REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	23	1.44e-02	2.95e-01	2.18e-01
REACTOME MET ACTIVATES PTPN11	5	1.44e-02	-6.32e-01	2.18e-01
REACTOME PROGRAMMED CELL DEATH	204	1.45e-02	-9.93e-02	2.18e-01
REACTOME COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING	32	1.49e-02	-2.49e-01	2.22e-01
REACTOME SIGNALING BY SCF KIT	42	1.50e-02	-2.17e-01	2.22e-01
REACTOME GASTRULATION	49	1.52e-02	-2.00e-01	2.23e-01
REACTOME EGFR INTERACTS WITH PHOSPHOLIPASE C GAMMA	9	1.53e-02	-4.67e-01	2.23e-01
REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES	39	1.55e-02	-2.24e-01	2.23e-01
REACTOME SIGNALING BY NUCLEAR RECEPTORS	283	1.58e-02	-8.34e-02	2.25e-01
REACTOME LTC4 CYSLTR MEDIATED IL4 PRODUCTION	6	1.59e-02	5.68e-01	2.25e-01
REACTOME FORMATION OF LATERAL PLATE MESODERM	5	1.62e-02	-6.21e-01	2.27e-01
REACTOME PI3K EVENTS IN ERBB2 SIGNALING	16	1.69e-02	-3.45e-01	2.35e-01
REACTOME ARACHIDONATE PRODUCTION FROM DAG	5	1.70e-02	6.16e-01	2.35e-01
REACTOME HDL ASSEMBLY	8	1.75e-02	4.85e-01	2.39e-01
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	263	1.77e-02	-8.50e-02	2.40e-01
REACTOME FC EPSILON RECEPTOR FCERI SIGNALING	127	1.78e-02	-1.22e-01	2.40e-01
REACTOME CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND	16	1.82e-02	-3.41e-01	2.43e-01
REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	80	1.84e-02	-1.52e-01	2.43e-01
REACTOME PHOSPHOLIPID METABOLISM	201	1.87e-02	9.62e-02	2.43e-01
REACTOME FLT3 SIGNALING IN DISEASE	28	1.88e-02	-2.57e-01	2.43e-01
REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3	59	1.89e-02	-1.77e-01	2.43e-01
REACTOME TRANSPORT OF SMALL MOLECULES	697	1.90e-02	5.21e-02	2.43e-01
REACTOME SARS COV 2 HOST INTERACTIONS	191	1.95e-02	-9.80e-02	2.46e-01
REACTOME CHROMOSOME MAINTENANCE	130	1.95e-02	-1.19e-01	2.46e-01
REACTOME RNA POLYMERASE I PROMOTER ESCAPE	83	1.98e-02	-1.48e-01	2.48e-01
REACTOME INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING	103	2.06e-02	-1.32e-01	2.54e-01
REACTOME PROTEIN UBIQUITINATION	76	2.07e-02	-1.54e-01	2.54e-01
REACTOME PROSTANOID LIGAND RECEPTORS	9	2.07e-02	-4.45e-01	2.54e-01
REACTOME APOPTOSIS	173	2.09e-02	-1.02e-01	2.54e-01
REACTOME SENSORY PERCEPTION OF TASTE	47	2.10e-02	1.95e-01	2.54e-01
REACTOME CELL CYCLE	666	2.13e-02	-5.23e-02	2.55e-01
REACTOME DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE	76	2.16e-02	-1.52e-01	2.55e-01
REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS	188	2.17e-02	-9.71e-02	2.55e-01
REACTOME OPSINS	7	2.18e-02	5.01e-01	2.55e-01
REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS	29	2.21e-02	-2.46e-01	2.55e-01
REACTOME HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR IN THE PRESENCE OF LIGAND	55	2.21e-02	-1.78e-01	2.55e-01
REACTOME SYNDECAN INTERACTIONS	26	2.31e-02	2.57e-01	2.55e-01
REACTOME FORMATION OF THE CORNIFIED ENVELOPE	125	2.33e-02	1.17e-01	2.55e-01
REACTOME NRAGE SIGNALS DEATH THROUGH JNK	53	2.34e-02	1.80e-01	2.55e-01
REACTOME NGF STIMULATED TRANSCRIPTION	38	2.35e-02	-2.12e-01	2.55e-01
REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	20	2.35e-02	-2.93e-01	2.55e-01
REACTOME APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS	87	2.36e-02	-1.40e-01	2.55e-01
REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES	18	2.37e-02	3.08e-01	2.55e-01
REACTOME METALLOPROTEASE DUBS	36	2.40e-02	-2.17e-01	2.55e-01
REACTOME STIMULI SENSING CHANNELS	100	2.43e-02	1.30e-01	2.55e-01
REACTOME CLEC7A DECTIN 1 SIGNALING	97	2.43e-02	-1.32e-01	2.55e-01
REACTOME MAPK FAMILY SIGNALING CASCADES	314	2.46e-02	-7.38e-02	2.55e-01
REACTOME TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE	10	2.47e-02	4.10e-01	2.55e-01
REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS	113	2.49e-02	-1.22e-01	2.55e-01
REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS	83	2.49e-02	-1.42e-01	2.55e-01
REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	14	2.50e-02	-3.46e-01	2.55e-01
REACTOME FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS	8	2.51e-02	-4.57e-01	2.55e-01
REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	59	2.51e-02	-1.69e-01	2.55e-01
REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION	62	2.51e-02	-1.64e-01	2.55e-01
REACTOME THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT	77	2.52e-02	-1.48e-01	2.55e-01
REACTOME ESR MEDIATED SIGNALING	210	2.52e-02	-8.96e-02	2.55e-01
REACTOME CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER	25	2.56e-02	2.58e-01	2.58e-01
REACTOME DIGESTION	17	2.57e-02	3.12e-01	2.58e-01
REACTOME MRNA SPLICING	197	2.64e-02	-9.17e-02	2.63e-01
REACTOME ESTROGEN DEPENDENT GENE EXPRESSION	140	2.67e-02	-1.08e-01	2.64e-01
REACTOME ER QUALITY CONTROL COMPARTMENT ERQC	21	2.71e-02	-2.79e-01	2.65e-01
REACTOME RESPIRATORY ELECTRON TRANSPORT	90	2.73e-02	-1.35e-01	2.65e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX2	117	2.73e-02	-1.18e-01	2.65e-01
REACTOME CLEC7A INFLAMMASOME PATHWAY	6	2.77e-02	-5.19e-01	2.67e-01
REACTOME UB SPECIFIC PROCESSING PROTEASES	187	2.83e-02	-9.30e-02	2.67e-01
REACTOME AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA	54	2.85e-02	-1.72e-01	2.67e-01
REACTOME E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS	58	2.86e-02	-1.66e-01	2.67e-01
REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT	159	2.86e-02	-1.01e-01	2.67e-01
REACTOME SIGNALING BY EGFR	49	2.90e-02	-1.80e-01	2.67e-01
REACTOME DISEASES OF PROGRAMMED CELL DEATH	96	2.91e-02	-1.29e-01	2.67e-01
REACTOME MODULATION BY MTB OF HOST IMMUNE SYSTEM	6	2.91e-02	-5.14e-01	2.67e-01
REACTOME DRUG MEDIATED INHIBITION OF CDK4 CDK6 ACTIVITY	5	2.94e-02	-5.63e-01	2.67e-01
REACTOME ADRENOCEPTORS	9	2.94e-02	-4.19e-01	2.67e-01
REACTOME FLT3 SIGNALING	38	2.94e-02	-2.04e-01	2.67e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING	5	2.95e-02	-5.62e-01	2.67e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH PI3K	7	2.97e-02	-4.74e-01	2.68e-01
REACTOME MET ACTIVATES RAP1 AND RAC1	11	3.12e-02	-3.75e-01	2.79e-01
REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING	32	3.13e-02	-2.20e-01	2.79e-01
REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	53	3.15e-02	-1.71e-01	2.79e-01
REACTOME MYD88 INDEPENDENT TLR4 CASCADE	103	3.17e-02	-1.23e-01	2.79e-01
REACTOME PRE NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM	6	3.17e-02	5.06e-01	2.79e-01
REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	17	3.20e-02	-3.00e-01	2.80e-01
REACTOME BETA OXIDATION OF BUTANOYL COA TO ACETYL COA	5	3.23e-02	5.53e-01	2.80e-01
REACTOME VASOPRESSIN LIKE RECEPTORS	5	3.36e-02	-5.49e-01	2.89e-01
REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION	8	3.37e-02	4.34e-01	2.89e-01
REACTOME PYROPTOSIS	27	3.38e-02	-2.36e-01	2.89e-01
REACTOME THE PHOTOTRANSDUCTION CASCADE	32	3.40e-02	2.17e-01	2.89e-01
REACTOME NTRK2 ACTIVATES RAC1	5	3.46e-02	-5.46e-01	2.93e-01
REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION	145	3.53e-02	-1.01e-01	2.97e-01
REACTOME ABC TRANSPORTER DISORDERS	76	3.59e-02	-1.39e-01	3.01e-01
REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	13	3.62e-02	3.36e-01	3.01e-01
REACTOME REGULATION BY C FLIP	11	3.70e-02	-3.63e-01	3.04e-01
REACTOME M PHASE	398	3.70e-02	-6.09e-02	3.04e-01
REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY	72	3.71e-02	-1.42e-01	3.04e-01
REACTOME SYNTHESIS OF 15 EICOSATETRAENOIC ACID DERIVATIVES	6	3.72e-02	-4.91e-01	3.04e-01
REACTOME PROTEIN FOLDING	96	3.75e-02	-1.23e-01	3.05e-01
REACTOME SIGNALING BY THE B CELL RECEPTOR BCR	106	3.80e-02	-1.17e-01	3.08e-01
REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	22	3.84e-02	-2.55e-01	3.09e-01
REACTOME BASE EXCISION REPAIR AP SITE FORMATION	59	3.93e-02	-1.55e-01	3.15e-01
REACTOME STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS	10	4.01e-02	-3.75e-01	3.20e-01
REACTOME TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY	16	4.03e-02	-2.96e-01	3.20e-01
REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB	5	4.10e-02	-5.28e-01	3.24e-01
REACTOME PROCESSING OF DNA DOUBLE STRAND BREAK ENDS	93	4.15e-02	-1.22e-01	3.24e-01
REACTOME THE NLRP3 INFLAMMASOME	16	4.15e-02	-2.94e-01	3.24e-01
REACTOME TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS	26	4.16e-02	-2.31e-01	3.24e-01
REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION	26	4.21e-02	-2.30e-01	3.26e-01
REACTOME RHO GTPASES ACTIVATE IQGAPS	31	4.23e-02	-2.11e-01	3.26e-01
REACTOME MET ACTIVATES PI3K AKT SIGNALING	6	4.29e-02	-4.77e-01	3.28e-01
REACTOME INTERLEUKIN 35 SIGNALLING	12	4.33e-02	-3.37e-01	3.28e-01
REACTOME CHREBP ACTIVATES METABOLIC GENE EXPRESSION	8	4.36e-02	4.12e-01	3.28e-01
REACTOME PI 3K CASCADE FGFR1	21	4.36e-02	-2.54e-01	3.28e-01
REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	16	4.37e-02	-2.91e-01	3.28e-01
REACTOME RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES TREGS	9	4.40e-02	-3.88e-01	3.28e-01
REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION	60	4.41e-02	-1.50e-01	3.28e-01
REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS	6	4.42e-02	-4.74e-01	3.28e-01
REACTOME PINK1 PRKN MEDIATED MITOPHAGY	22	4.43e-02	-2.48e-01	3.28e-01
REACTOME HYALURONAN METABOLISM	17	4.51e-02	2.81e-01	3.28e-01
REACTOME ADHERENS JUNCTIONS INTERACTIONS	33	4.51e-02	-2.01e-01	3.28e-01
REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS	21	4.52e-02	-2.52e-01	3.28e-01
REACTOME G2 M CHECKPOINTS	162	4.52e-02	-9.12e-02	3.28e-01
REACTOME SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE	91	4.56e-02	-1.21e-01	3.28e-01
REACTOME DISEASES ASSOCIATED WITH SURFACTANT METABOLISM	9	4.57e-02	3.85e-01	3.28e-01
REACTOME CELLULAR SENESCENCE	189	4.59e-02	-8.42e-02	3.28e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY	19	4.60e-02	2.64e-01	3.28e-01
REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION	84	4.73e-02	-1.25e-01	3.34e-01
REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	16	4.73e-02	-2.86e-01	3.34e-01
REACTOME DISEASES OF METABOLISM	237	4.76e-02	7.47e-02	3.34e-01
REACTOME FCERI MEDIATED NF KB ACTIVATION	78	4.77e-02	-1.30e-01	3.34e-01
REACTOME MET ACTIVATES PTK2 SIGNALING	30	4.78e-02	2.09e-01	3.34e-01
REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	111	4.82e-02	-1.09e-01	3.35e-01
REACTOME DNA METHYLATION	58	4.85e-02	-1.50e-01	3.35e-01
REACTOME NEGATIVE REGULATION OF FLT3	15	4.86e-02	-2.94e-01	3.35e-01
REACTOME SIGNALING BY ACTIVIN	15	4.87e-02	-2.94e-01	3.35e-01
REACTOME TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7	12	4.93e-02	-3.28e-01	3.37e-01
REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION	19	4.98e-02	2.60e-01	3.39e-01
REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE	63	5.00e-02	-1.43e-01	3.39e-01
REACTOME SHC1 EVENTS IN ERBB2 SIGNALING	22	5.02e-02	-2.41e-01	3.39e-01
REACTOME NUCLEAR SIGNALING BY ERBB4	32	5.08e-02	-1.99e-01	3.41e-01
REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH	62	5.09e-02	1.43e-01	3.41e-01
REACTOME SIGNALING BY NOTCH2	32	5.11e-02	-1.99e-01	3.41e-01
REACTOME ERBB2 ACTIVATES PTK6 SIGNALING	13	5.14e-02	-3.12e-01	3.42e-01
REACTOME NEF MEDIATED CD8 DOWN REGULATION	7	5.21e-02	4.24e-01	3.45e-01
REACTOME HEDGEHOG LIGAND BIOGENESIS	64	5.29e-02	-1.40e-01	3.46e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION TERMINATION	23	5.31e-02	-2.33e-01	3.46e-01
REACTOME ENDOSOMAL VACUOLAR PATHWAY	11	5.31e-02	-3.37e-01	3.46e-01
REACTOME COLLAGEN CHAIN TRIMERIZATION	42	5.31e-02	1.72e-01	3.46e-01
REACTOME CHYLOMICRON REMODELING	10	5.34e-02	3.53e-01	3.46e-01
REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE	109	5.35e-02	-1.07e-01	3.46e-01
REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	73	5.37e-02	-1.31e-01	3.46e-01
REACTOME INTERLEUKIN 9 SIGNALING	7	5.39e-02	-4.21e-01	3.46e-01
REACTOME INFLAMMASOMES	21	5.45e-02	-2.42e-01	3.48e-01
REACTOME TOLL LIKE RECEPTOR 9 TLR9 CASCADE	100	5.49e-02	-1.11e-01	3.50e-01
REACTOME MITOTIC G2 G2 M PHASES	194	5.59e-02	-7.96e-02	3.55e-01
REACTOME SIGNALING BY RECEPTOR TYROSINE KINASES	507	5.62e-02	-4.95e-02	3.55e-01
REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION	90	5.64e-02	-1.16e-01	3.55e-01
REACTOME INTERLEUKIN 12 FAMILY SIGNALING	53	5.81e-02	-1.50e-01	3.64e-01
REACTOME EFFECTS OF PIP2 HYDROLYSIS	26	5.87e-02	2.14e-01	3.66e-01
REACTOME PIWI INTERACTING RNA PIRNA BIOGENESIS	29	5.89e-02	2.03e-01	3.66e-01
REACTOME DNA DOUBLE STRAND BREAK REPAIR	162	6.00e-02	-8.56e-02	3.72e-01
REACTOME VITAMIN C ASCORBATE METABOLISM	8	6.03e-02	-3.84e-01	3.72e-01
REACTOME TELOMERE MAINTENANCE	106	6.09e-02	-1.05e-01	3.73e-01
REACTOME FCERI MEDIATED CA 2 MOBILIZATION	30	6.11e-02	-1.98e-01	3.73e-01
REACTOME HOMOLOGY DIRECTED REPAIR	132	6.12e-02	-9.44e-02	3.73e-01
REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS	66	6.13e-02	1.33e-01	3.73e-01
REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT	236	6.15e-02	7.07e-02	3.73e-01
REACTOME MATURATION OF PROTEIN 3A	9	6.19e-02	3.59e-01	3.74e-01
REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX	15	6.24e-02	-2.78e-01	3.74e-01
REACTOME ORC1 REMOVAL FROM CHROMATIN	70	6.25e-02	-1.29e-01	3.74e-01
REACTOME HDR THROUGH SINGLE STRAND ANNEALING SSA	37	6.27e-02	-1.77e-01	3.74e-01
REACTOME SYNTHESIS OF DNA	119	6.37e-02	-9.84e-02	3.79e-01
REACTOME REGULATION OF IFNG SIGNALING	14	6.39e-02	-2.86e-01	3.79e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION	29	6.44e-02	1.98e-01	3.80e-01
REACTOME HYDROLYSIS OF LPC	9	6.48e-02	3.55e-01	3.82e-01
REACTOME MATURATION OF SARS COV 2 SPIKE PROTEIN	35	6.56e-02	1.80e-01	3.85e-01
REACTOME PRC2 METHYLATES HISTONES AND DNA	65	6.60e-02	-1.32e-01	3.86e-01
REACTOME SIGNALING BY ERBB2 IN CANCER	26	6.64e-02	-2.08e-01	3.86e-01
REACTOME AMYLOID FIBER FORMATION	102	6.67e-02	-1.05e-01	3.86e-01
REACTOME FORMATION OF INCISION COMPLEX IN GG NER	40	6.67e-02	-1.68e-01	3.86e-01
REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	54	6.70e-02	-1.44e-01	3.86e-01
REACTOME S PHASE	159	6.83e-02	-8.38e-02	3.91e-01
REACTOME SMOOTH MUSCLE CONTRACTION	43	6.84e-02	1.61e-01	3.91e-01
REACTOME SIGNALING BY FLT3 ITD AND TKD MUTANTS	16	6.93e-02	-2.62e-01	3.93e-01
REACTOME CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY	25	6.94e-02	-2.10e-01	3.93e-01
REACTOME INACTIVATION OF CSF3 G CSF SIGNALING	25	6.94e-02	-2.10e-01	3.93e-01
REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE	5	6.97e-02	4.68e-01	3.93e-01
REACTOME INTERLEUKIN 15 SIGNALING	13	6.98e-02	-2.90e-01	3.93e-01
REACTOME TRANSPORT OF FATTY ACIDS	8	7.01e-02	3.70e-01	3.93e-01
REACTOME ACYL CHAIN REMODELLING OF PS	22	7.07e-02	2.23e-01	3.95e-01
REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	37	7.22e-02	-1.71e-01	4.01e-01
REACTOME CELL CYCLE CHECKPOINTS	284	7.23e-02	-6.20e-02	4.01e-01
REACTOME SIGNALING BY NOTCH4	80	7.26e-02	-1.16e-01	4.01e-01
REACTOME SIGNALING BY FGFR	85	7.30e-02	-1.12e-01	4.02e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	11	7.39e-02	-3.11e-01	4.06e-01
REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	353	7.46e-02	-5.52e-02	4.08e-01
REACTOME SIGNALING BY KIT IN DISEASE	20	7.52e-02	-2.30e-01	4.10e-01
REACTOME TOLL LIKE RECEPTOR CASCADES	158	7.55e-02	-8.19e-02	4.10e-01
REACTOME MUCOPOLYSACCHARIDOSES	10	7.58e-02	3.24e-01	4.11e-01
REACTOME PROTEIN REPAIR	6	7.61e-02	-4.18e-01	4.11e-01
REACTOME ALK MUTANTS BIND TKIS	12	7.66e-02	-2.95e-01	4.12e-01
REACTOME CONDENSATION OF PROPHASE CHROMOSOMES	66	7.71e-02	-1.26e-01	4.14e-01
REACTOME TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX	10	7.75e-02	-3.22e-01	4.14e-01
REACTOME ETHANOL OXIDATION	12	7.87e-02	-2.93e-01	4.17e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION	102	7.88e-02	-1.01e-01	4.17e-01
REACTOME REGULATION OF BACH1 ACTIVITY	11	7.90e-02	-3.06e-01	4.17e-01
REACTOME AGGREPHAGY	42	7.91e-02	-1.57e-01	4.17e-01
REACTOME SIGNALING BY FGFR3	39	7.93e-02	-1.62e-01	4.17e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS	9	7.96e-02	3.37e-01	4.17e-01
REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES	27	8.07e-02	-1.94e-01	4.22e-01
REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING	28	8.14e-02	-1.90e-01	4.25e-01
REACTOME SYNTHESIS OF 5 EICOSATETRAENOIC ACIDS	9	8.21e-02	-3.35e-01	4.26e-01
REACTOME HISTIDINE CATABOLISM	8	8.23e-02	3.55e-01	4.26e-01
REACTOME TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE	20	8.28e-02	-2.24e-01	4.28e-01
REACTOME SPRY REGULATION OF FGF SIGNALING	16	8.40e-02	-2.49e-01	4.31e-01
REACTOME INTERLEUKIN 17 SIGNALING	66	8.41e-02	-1.23e-01	4.31e-01
REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	101	8.50e-02	9.92e-02	4.32e-01
REACTOME TIE2 SIGNALING	18	8.51e-02	-2.34e-01	4.32e-01
REACTOME PEPTIDE HORMONE METABOLISM	84	8.54e-02	-1.09e-01	4.32e-01
REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE	52	8.55e-02	-1.38e-01	4.32e-01
REACTOME SARS COV 2 ACTIVATES MODULATES INNATE AND ADAPTIVE IMMUNE RESPONSES	118	8.59e-02	-9.15e-02	4.32e-01
REACTOME LAMININ INTERACTIONS	28	8.62e-02	1.87e-01	4.32e-01
REACTOME REGULATION OF FZD BY UBIQUITINATION	21	8.64e-02	-2.16e-01	4.32e-01
REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	13	8.64e-02	-2.75e-01	4.32e-01
REACTOME ECM PROTEOGLYCANS	73	8.68e-02	1.16e-01	4.32e-01
REACTOME HEDGEHOG ON STATE	85	8.68e-02	-1.07e-01	4.32e-01
REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	20	8.78e-02	2.20e-01	4.35e-01
REACTOME SIGNALING BY HEDGEHOG	148	8.79e-02	-8.13e-02	4.35e-01
REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS	63	8.82e-02	-1.24e-01	4.35e-01
REACTOME CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY	84	8.96e-02	-1.07e-01	4.39e-01
REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	86	8.98e-02	-1.06e-01	4.39e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE	74	8.99e-02	1.14e-01	4.39e-01
REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS	16	9.03e-02	2.45e-01	4.40e-01
REACTOME INTERLEUKIN 27 SIGNALING	11	9.09e-02	-2.94e-01	4.40e-01
REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER	81	9.14e-02	-1.08e-01	4.40e-01
REACTOME G1 S DNA DAMAGE CHECKPOINTS	67	9.16e-02	-1.19e-01	4.40e-01
REACTOME SENSORY PERCEPTION OF SALTY TASTE	6	9.16e-02	3.98e-01	4.40e-01
REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	67	9.17e-02	-1.19e-01	4.40e-01
REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING	33	9.21e-02	-1.69e-01	4.41e-01
REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4	33	9.31e-02	1.69e-01	4.44e-01
REACTOME SHC MEDIATED CASCADE FGFR1	21	9.35e-02	-2.11e-01	4.45e-01
REACTOME ION TRANSPORT BY P TYPE ATPASES	51	9.46e-02	1.35e-01	4.49e-01
REACTOME RHOBTB1 GTPASE CYCLE	22	9.58e-02	-2.05e-01	4.52e-01
REACTOME HCMV INFECTION	152	9.58e-02	-7.83e-02	4.52e-01
REACTOME DNA DAMAGE BYPASS	47	9.63e-02	-1.40e-01	4.53e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	28	9.65e-02	-1.81e-01	4.53e-01
REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	98	9.72e-02	-9.70e-02	4.55e-01
REACTOME CARGO CONCENTRATION IN THE ER	32	9.88e-02	-1.69e-01	4.56e-01
REACTOME OXIDATIVE STRESS INDUCED SENESCENCE	118	9.90e-02	-8.79e-02	4.56e-01
REACTOME PI METABOLISM	79	9.90e-02	1.07e-01	4.56e-01
REACTOME NCAM1 INTERACTIONS	41	9.92e-02	1.49e-01	4.56e-01
REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	51	9.95e-02	-1.33e-01	4.56e-01
REACTOME STAT5 ACTIVATION	7	9.95e-02	-3.59e-01	4.56e-01
REACTOME SIGNALING BY PDGFR IN DISEASE	20	9.96e-02	-2.13e-01	4.56e-01
REACTOME REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS	15	1.01e-01	-2.45e-01	4.56e-01
REACTOME ASPIRIN ADME	42	1.01e-01	1.46e-01	4.56e-01
REACTOME GP1B IX V ACTIVATION SIGNALLING	11	1.01e-01	-2.86e-01	4.56e-01
REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	15	1.01e-01	-2.45e-01	4.56e-01
REACTOME DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING	61	1.01e-01	-1.21e-01	4.56e-01
REACTOME REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM	11	1.01e-01	2.86e-01	4.56e-01
REACTOME CYTOPROTECTION BY HMOX1	59	1.02e-01	-1.23e-01	4.59e-01
REACTOME 2 LTR CIRCLE FORMATION	7	1.04e-01	-3.55e-01	4.65e-01
REACTOME DISEASES OF GLYCOSYLATION	137	1.04e-01	8.04e-02	4.65e-01
REACTOME ONCOGENE INDUCED SENESCENCE	35	1.04e-01	-1.59e-01	4.65e-01
REACTOME ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA	5	1.05e-01	4.19e-01	4.65e-01
REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	123	1.05e-01	8.47e-02	4.65e-01
REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT	222	1.05e-01	-6.31e-02	4.65e-01
REACTOME TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT	18	1.06e-01	-2.20e-01	4.66e-01
REACTOME INTERLEUKIN 6 FAMILY SIGNALING	24	1.06e-01	-1.91e-01	4.66e-01
REACTOME ACYL CHAIN REMODELLING OF PC	27	1.06e-01	1.80e-01	4.66e-01
REACTOME RHO GTPASES ACTIVATE PKNS	86	1.07e-01	-1.01e-01	4.66e-01
REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION	31	1.07e-01	-1.67e-01	4.66e-01
REACTOME SIGNALING BY FLT3 FUSION PROTEINS	19	1.07e-01	-2.14e-01	4.66e-01
REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	99	1.08e-01	-9.36e-02	4.67e-01
REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	15	1.08e-01	-2.40e-01	4.67e-01
REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	28	1.09e-01	-1.75e-01	4.69e-01
REACTOME FGFR2 LIGAND BINDING AND ACTIVATION	19	1.09e-01	-2.12e-01	4.70e-01
REACTOME INTESTINAL ABSORPTION	5	1.10e-01	4.13e-01	4.71e-01
REACTOME ASSEMBLY OF THE HIV VIRION	16	1.10e-01	-2.31e-01	4.71e-01
REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	76	1.10e-01	1.06e-01	4.71e-01
REACTOME O LINKED GLYCOSYLATION	109	1.12e-01	8.81e-02	4.77e-01
REACTOME IRAK1 RECRUITS IKK COMPLEX	12	1.12e-01	-2.65e-01	4.78e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH RAS	9	1.14e-01	-3.04e-01	4.83e-01
REACTOME NEGATIVE REGULATION OF NOTCH4 SIGNALING	53	1.15e-01	-1.25e-01	4.83e-01
REACTOME MITOTIC PROPHASE	134	1.15e-01	-7.89e-02	4.83e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS	5	1.15e-01	-4.07e-01	4.83e-01
REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	22	1.15e-01	-1.94e-01	4.83e-01
REACTOME HIV INFECTION	223	1.16e-01	-6.11e-02	4.83e-01
REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	22	1.16e-01	-1.94e-01	4.83e-01
REACTOME DAG AND IP3 SIGNALING	40	1.16e-01	1.44e-01	4.83e-01
REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP	41	1.16e-01	1.42e-01	4.83e-01
REACTOME DEGRADATION OF DVL	56	1.18e-01	-1.21e-01	4.86e-01
REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM	23	1.19e-01	-1.88e-01	4.86e-01
REACTOME MITOTIC METAPHASE AND ANAPHASE	228	1.19e-01	-5.99e-02	4.86e-01
REACTOME CELLULAR RESPONSE TO HYPOXIA	74	1.19e-01	-1.05e-01	4.86e-01
REACTOME SIGNAL AMPLIFICATION	33	1.19e-01	-1.57e-01	4.86e-01
REACTOME HDR THROUGH HOMOLOGOUS RECOMBINATION HRR	66	1.19e-01	-1.11e-01	4.86e-01
REACTOME SEPARATION OF SISTER CHROMATIDS	184	1.19e-01	-6.66e-02	4.86e-01
REACTOME METABOLISM OF FAT SOLUBLE VITAMINS	46	1.19e-01	1.33e-01	4.86e-01
REACTOME PKMTS METHYLATE HISTONE LYSINES	64	1.20e-01	1.12e-01	4.86e-01
REACTOME UCH PROTEINASES	99	1.20e-01	-9.04e-02	4.86e-01
REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	79	1.20e-01	-1.01e-01	4.86e-01
REACTOME HCMV EARLY EVENTS	128	1.21e-01	-7.94e-02	4.86e-01
REACTOME CHOLESTEROL BIOSYNTHESIS	25	1.21e-01	1.79e-01	4.86e-01
REACTOME PYRIMIDINE SALVAGE	10	1.22e-01	-2.83e-01	4.86e-01
REACTOME SEROTONIN RECEPTORS	11	1.22e-01	-2.70e-01	4.86e-01
REACTOME G2 M DNA DAMAGE CHECKPOINT	90	1.22e-01	-9.44e-02	4.86e-01
REACTOME DISEASES OF DNA REPAIR	51	1.24e-01	-1.25e-01	4.92e-01
REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION	11	1.24e-01	-2.68e-01	4.92e-01
REACTOME SARS COV 2 INFECTION	281	1.24e-01	-5.33e-02	4.93e-01
REACTOME RECYCLING OF EIF2 GDP	7	1.25e-01	-3.35e-01	4.93e-01
REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	16	1.25e-01	-2.22e-01	4.93e-01
REACTOME NEGATIVE REGULATION OF MAPK PATHWAY	41	1.26e-01	-1.38e-01	4.95e-01
REACTOME PTK6 PROMOTES HIF1A STABILIZATION	6	1.26e-01	-3.61e-01	4.95e-01
REACTOME G ALPHA 12 13 SIGNALLING EVENTS	74	1.26e-01	1.03e-01	4.95e-01
REACTOME APOPTOTIC EXECUTION PHASE	49	1.27e-01	-1.26e-01	4.96e-01
REACTOME PI 3K CASCADE FGFR3	17	1.27e-01	-2.14e-01	4.96e-01
REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX	9	1.28e-01	-2.93e-01	4.98e-01
REACTOME IRON UPTAKE AND TRANSPORT	56	1.28e-01	-1.17e-01	4.98e-01
REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY	26	1.29e-01	1.72e-01	4.98e-01
REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION	68	1.30e-01	-1.06e-01	5.00e-01
REACTOME TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE	39	1.30e-01	-1.40e-01	5.00e-01
REACTOME BICARBONATE TRANSPORTERS	10	1.30e-01	2.76e-01	5.00e-01
REACTOME PARACETAMOL ADME	26	1.31e-01	1.71e-01	5.01e-01
REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS	100	1.31e-01	-8.74e-02	5.01e-01
REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	20	1.31e-01	1.95e-01	5.01e-01
REACTOME NEGATIVE REGULATION OF MET ACTIVITY	20	1.32e-01	-1.95e-01	5.01e-01
REACTOME RNA POLYMERASE III CHAIN ELONGATION	18	1.33e-01	-2.05e-01	5.01e-01
REACTOME MET RECEPTOR RECYCLING	10	1.33e-01	-2.75e-01	5.01e-01
REACTOME HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE	43	1.33e-01	-1.32e-01	5.01e-01
REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	129	1.33e-01	-7.65e-02	5.01e-01
REACTOME TRNA PROCESSING	105	1.33e-01	-8.48e-02	5.01e-01
REACTOME DEFECTIVE CSF2RB CAUSES SMDP5	7	1.34e-01	3.27e-01	5.01e-01
REACTOME MEIOSIS	110	1.34e-01	-8.27e-02	5.01e-01
REACTOME CHYLOMICRON ASSEMBLY	10	1.34e-01	2.74e-01	5.01e-01
REACTOME MUSCLE CONTRACTION	197	1.35e-01	6.18e-02	5.03e-01
REACTOME MITOCHONDRIAL TRANSLATION	93	1.35e-01	-8.96e-02	5.03e-01
REACTOME CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS	19	1.36e-01	-1.97e-01	5.07e-01
REACTOME LYSINE CATABOLISM	12	1.38e-01	-2.47e-01	5.13e-01
REACTOME SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA PHE	6	1.39e-01	-3.48e-01	5.15e-01
REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE	71	1.41e-01	-1.01e-01	5.19e-01
REACTOME VITAMIN B1 THIAMIN METABOLISM	5	1.41e-01	-3.80e-01	5.20e-01
REACTOME MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION	15	1.42e-01	-2.19e-01	5.21e-01
REACTOME TERMINATION OF TRANSLESION DNA SYNTHESIS	32	1.42e-01	-1.50e-01	5.22e-01
REACTOME TAK1 DEPENDENT IKK AND NF KAPPA B ACTIVATION	41	1.43e-01	-1.32e-01	5.23e-01
REACTOME HYALURONAN UPTAKE AND DEGRADATION	12	1.44e-01	2.44e-01	5.24e-01
REACTOME TRANSCRIPTIONAL REGULATION BY TP53	351	1.44e-01	-4.53e-02	5.25e-01
REACTOME RIPK1 MEDIATED REGULATED NECROSIS	30	1.46e-01	-1.53e-01	5.25e-01
REACTOME SIGNALING BY CSF1 M CSF IN MYELOID CELLS	30	1.46e-01	-1.53e-01	5.25e-01
REACTOME RELAXIN RECEPTORS	8	1.46e-01	-2.97e-01	5.25e-01
REACTOME ERBB2 REGULATES CELL MOTILITY	15	1.47e-01	-2.16e-01	5.25e-01
REACTOME G2 PHASE	5	1.47e-01	-3.74e-01	5.25e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION	41	1.48e-01	-1.31e-01	5.25e-01
REACTOME HIV LIFE CYCLE	145	1.48e-01	-6.96e-02	5.25e-01
REACTOME TLR3 MEDIATED TICAM1 DEPENDENT PROGRAMMED CELL DEATH	6	1.48e-01	-3.41e-01	5.25e-01
REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	19	1.48e-01	-1.92e-01	5.25e-01
REACTOME INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL	14	1.49e-01	-2.23e-01	5.25e-01
REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF	53	1.49e-01	1.15e-01	5.25e-01
REACTOME HSF1 ACTIVATION	29	1.49e-01	-1.55e-01	5.25e-01
REACTOME LATE ENDOSOMAL MICROAUTOPHAGY	33	1.49e-01	-1.45e-01	5.25e-01
REACTOME CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA	63	1.49e-01	-1.05e-01	5.25e-01
REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION	12	1.49e-01	-2.41e-01	5.25e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12	22	1.49e-01	-1.78e-01	5.25e-01
REACTOME SYNTHESIS OF PIPS AT THE ER MEMBRANE	5	1.50e-01	3.72e-01	5.25e-01
REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION	98	1.50e-01	-8.41e-02	5.25e-01
REACTOME PI 3K CASCADE FGFR2	22	1.50e-01	-1.77e-01	5.25e-01
REACTOME DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA	77	1.51e-01	-9.47e-02	5.25e-01
REACTOME CATION COUPLED CHLORIDE COTRANSPORTERS	7	1.51e-01	3.13e-01	5.25e-01
REACTOME CRISTAE FORMATION	27	1.52e-01	-1.59e-01	5.25e-01
REACTOME CITRIC ACID CYCLE TCA CYCLE	21	1.52e-01	-1.81e-01	5.25e-01
REACTOME INTERLEUKIN 6 SIGNALING	11	1.52e-01	-2.49e-01	5.25e-01
REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	26	1.53e-01	-1.62e-01	5.26e-01
REACTOME HYALURONAN BIOSYNTHESIS AND EXPORT	5	1.53e-01	3.69e-01	5.26e-01
REACTOME SARS COV INFECTIONS	392	1.54e-01	-4.20e-02	5.26e-01
REACTOME NONCANONICAL ACTIVATION OF NOTCH3	8	1.54e-01	-2.91e-01	5.26e-01
REACTOME SURFACTANT METABOLISM	28	1.54e-01	1.56e-01	5.26e-01
REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES	21	1.54e-01	1.80e-01	5.26e-01
REACTOME SIGNALING BY ALK IN CANCER	53	1.55e-01	-1.13e-01	5.27e-01
REACTOME SIGNALING BY NOTCH	234	1.56e-01	-5.39e-02	5.29e-01
REACTOME REGULATION OF GENE EXPRESSION IN ENDOCRINE COMMITTED NEUROG3 PROGENITOR CELLS	5	1.57e-01	-3.66e-01	5.31e-01
REACTOME PI3K AKT SIGNALING IN CANCER	103	1.57e-01	-8.06e-02	5.33e-01
REACTOME ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS	17	1.58e-01	-1.98e-01	5.34e-01
REACTOME DEFECTIVE GALNT3 CAUSES HFTC	16	1.59e-01	2.03e-01	5.36e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH CDC42	19	1.60e-01	-1.86e-01	5.38e-01
REACTOME SIGNALLING TO P38 VIA RIT AND RIN	5	1.61e-01	-3.62e-01	5.41e-01
REACTOME HCMV LATE EVENTS	110	1.61e-01	-7.73e-02	5.41e-01
REACTOME FRS MEDIATED FGFR1 SIGNALING	23	1.62e-01	-1.68e-01	5.43e-01
REACTOME REPRODUCTION	136	1.63e-01	-6.93e-02	5.43e-01
REACTOME NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	11	1.63e-01	-2.43e-01	5.43e-01
REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	38	1.64e-01	1.30e-01	5.45e-01
REACTOME INTEGRATION OF PROVIRUS	9	1.65e-01	-2.67e-01	5.45e-01
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION	361	1.65e-01	-4.26e-02	5.45e-01
REACTOME HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS	9	1.65e-01	2.67e-01	5.45e-01
REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	24	1.65e-01	-1.64e-01	5.45e-01
REACTOME CELL CELL JUNCTION ORGANIZATION	64	1.66e-01	-1.00e-01	5.45e-01
REACTOME DEGRADATION OF GLI1 BY THE PROTEASOME	59	1.66e-01	-1.04e-01	5.45e-01
REACTOME INLA MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS	9	1.67e-01	-2.66e-01	5.45e-01
REACTOME RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION	22	1.67e-01	-1.70e-01	5.45e-01
REACTOME ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS	7	1.67e-01	3.02e-01	5.45e-01
REACTOME P75NTR REGULATES AXONOGENESIS	9	1.67e-01	2.66e-01	5.45e-01
REACTOME CHYLOMICRON CLEARANCE	5	1.68e-01	3.56e-01	5.45e-01
REACTOME NUCLEAR EVENTS MEDIATED BY NFE2L2	77	1.68e-01	-9.09e-02	5.45e-01
REACTOME CGMP EFFECTS	16	1.68e-01	-1.99e-01	5.45e-01
REACTOME SIGNALING BY FGFR1	49	1.69e-01	-1.14e-01	5.45e-01
REACTOME JOSEPHIN DOMAIN DUBS	11	1.70e-01	-2.39e-01	5.48e-01
REACTOME DIGESTION OF DIETARY CARBOHYDRATE	6	1.70e-01	3.23e-01	5.48e-01
REACTOME MITOCHONDRIAL BIOGENESIS	87	1.71e-01	-8.50e-02	5.48e-01
REACTOME DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B	7	1.71e-01	-2.99e-01	5.48e-01
REACTOME NEUREXINS AND NEUROLIGINS	51	1.71e-01	-1.11e-01	5.48e-01
REACTOME SIGNALING BY RETINOIC ACID	41	1.73e-01	-1.23e-01	5.51e-01
REACTOME STABILIZATION OF P53	56	1.73e-01	-1.05e-01	5.51e-01
REACTOME VEGFR2 MEDIATED CELL PROLIFERATION	19	1.73e-01	1.80e-01	5.51e-01
REACTOME TRANSLESION SYNTHESIS BY POLH	19	1.74e-01	-1.80e-01	5.51e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE GIP	12	1.74e-01	-2.27e-01	5.51e-01
REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING	12	1.74e-01	2.26e-01	5.51e-01
REACTOME MAPK1 ERK2 ACTIVATION	9	1.75e-01	-2.61e-01	5.51e-01
REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	11	1.75e-01	-2.36e-01	5.51e-01
REACTOME SIGNALLING TO ERKS	34	1.75e-01	-1.34e-01	5.51e-01
REACTOME VXPX CARGO TARGETING TO CILIUM	20	1.77e-01	1.75e-01	5.54e-01
REACTOME FLT3 SIGNALING THROUGH SRC FAMILY KINASES	6	1.77e-01	-3.18e-01	5.54e-01
REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	23	1.77e-01	1.63e-01	5.54e-01
REACTOME O LINKED GLYCOSYLATION OF MUCINS	61	1.78e-01	9.98e-02	5.54e-01
REACTOME LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS	19	1.78e-01	-1.79e-01	5.54e-01
REACTOME AMINO ACIDS REGULATE MTORC1	53	1.79e-01	1.07e-01	5.54e-01
REACTOME ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA	9	1.80e-01	2.58e-01	5.54e-01
REACTOME COLLAGEN DEGRADATION	61	1.81e-01	9.91e-02	5.54e-01
REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	12	1.81e-01	2.23e-01	5.54e-01
REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	26	1.81e-01	-1.52e-01	5.54e-01
REACTOME REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA	15	1.81e-01	-1.99e-01	5.54e-01
REACTOME EPH EPHRIN MEDIATED REPULSION OF CELLS	50	1.81e-01	-1.09e-01	5.54e-01
REACTOME DNA REPAIR	321	1.81e-01	-4.34e-02	5.54e-01
REACTOME SCAVENGING BY CLASS F RECEPTORS	6	1.82e-01	-3.15e-01	5.54e-01
REACTOME ACTIVATION OF SMO	18	1.82e-01	-1.82e-01	5.54e-01
REACTOME SELECTIVE AUTOPHAGY	79	1.82e-01	-8.68e-02	5.54e-01
REACTOME TACHYKININ RECEPTORS BIND TACHYKININS	5	1.82e-01	3.44e-01	5.54e-01
REACTOME C TYPE LECTIN RECEPTORS CLRS	136	1.83e-01	-6.62e-02	5.54e-01
REACTOME HS GAG DEGRADATION	19	1.83e-01	1.76e-01	5.54e-01
REACTOME SIGNALING BY FGFR4	40	1.83e-01	-1.22e-01	5.54e-01
REACTOME DNA DAMAGE RECOGNITION IN GG NER	36	1.83e-01	-1.28e-01	5.54e-01
REACTOME RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK	47	1.84e-01	-1.12e-01	5.54e-01
REACTOME REGULATION OF RAS BY GAPS	66	1.85e-01	-9.43e-02	5.54e-01
REACTOME DNA REPLICATION INITIATION	7	1.85e-01	-2.89e-01	5.54e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS	11	1.85e-01	2.31e-01	5.54e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FYN	7	1.85e-01	-2.89e-01	5.54e-01
REACTOME FORMATION OF AXIAL MESODERM	14	1.86e-01	-2.04e-01	5.54e-01
REACTOME REGULATION OF NPAS4 MRNA TRANSLATION	9	1.86e-01	2.55e-01	5.54e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES	8	1.86e-01	-2.70e-01	5.54e-01
REACTOME BASE EXCISION REPAIR	87	1.87e-01	-8.19e-02	5.54e-01
REACTOME TRP CHANNELS	27	1.87e-01	1.47e-01	5.54e-01
REACTOME SIGNALING BY WNT	318	1.89e-01	-4.29e-02	5.58e-01
REACTOME HDACS DEACETYLATE HISTONES	85	1.89e-01	-8.24e-02	5.58e-01
REACTOME NUCLEOTIDE CATABOLISM	35	1.89e-01	-1.28e-01	5.58e-01
REACTOME NS1 MEDIATED EFFECTS ON HOST PATHWAYS	41	1.89e-01	-1.18e-01	5.58e-01
REACTOME TRIF MEDIATED PROGRAMMED CELL DEATH	9	1.90e-01	-2.52e-01	5.58e-01
REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS	28	1.91e-01	-1.43e-01	5.58e-01
REACTOME CAMK IV MEDIATED PHOSPHORYLATION OF CREB	10	1.91e-01	2.39e-01	5.58e-01
REACTOME KERATINIZATION	210	1.91e-01	5.24e-02	5.58e-01
REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING	30	1.92e-01	-1.38e-01	5.60e-01
REACTOME NOD1 2 SIGNALING PATHWAY	33	1.93e-01	-1.31e-01	5.64e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1	25	1.95e-01	-1.50e-01	5.67e-01
REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	32	1.96e-01	-1.32e-01	5.69e-01
REACTOME INTERLEUKIN 1 PROCESSING	9	1.96e-01	-2.49e-01	5.69e-01
REACTOME FGFR1C LIGAND BINDING AND ACTIVATION	11	1.98e-01	-2.24e-01	5.72e-01
REACTOME TRIGLYCERIDE BIOSYNTHESIS	12	1.98e-01	2.15e-01	5.72e-01
REACTOME CDC42 GTPASE CYCLE	144	1.98e-01	6.21e-02	5.72e-01
REACTOME DERMATAN SULFATE BIOSYNTHESIS	10	2.00e-01	-2.34e-01	5.73e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING	6	2.00e-01	-3.02e-01	5.73e-01
REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS	12	2.01e-01	-2.13e-01	5.73e-01
REACTOME FCGR ACTIVATION	11	2.01e-01	-2.23e-01	5.73e-01
REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	24	2.01e-01	-1.51e-01	5.73e-01
REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	91	2.01e-01	7.76e-02	5.73e-01
REACTOME SYNTHESIS OF PA	38	2.01e-01	1.20e-01	5.73e-01
REACTOME SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL	8	2.01e-01	2.61e-01	5.73e-01
REACTOME PHENYLALANINE METABOLISM	6	2.04e-01	2.99e-01	5.80e-01
REACTOME INTERLEUKIN 7 SIGNALING	31	2.05e-01	-1.32e-01	5.80e-01
REACTOME SNRNP ASSEMBLY	53	2.05e-01	-1.01e-01	5.80e-01
REACTOME MET PROMOTES CELL MOTILITY	41	2.05e-01	1.14e-01	5.80e-01
REACTOME FLT3 SIGNALING BY CBL MUTANTS	7	2.06e-01	-2.76e-01	5.81e-01
REACTOME PTK6 REGULATES CELL CYCLE	6	2.07e-01	-2.97e-01	5.83e-01
REACTOME DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS	14	2.09e-01	-1.94e-01	5.88e-01
REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	19	2.09e-01	-1.66e-01	5.88e-01
REACTOME HDL CLEARANCE	5	2.10e-01	3.24e-01	5.88e-01
REACTOME DRUG ADME	103	2.10e-01	7.14e-02	5.88e-01
REACTOME GLYCEROPHOSPHOLIPID CATABOLISM	7	2.11e-01	2.73e-01	5.89e-01
REACTOME DISEASES OF MITOTIC CELL CYCLE	37	2.12e-01	-1.19e-01	5.92e-01
REACTOME ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY	10	2.13e-01	-2.28e-01	5.92e-01
REACTOME CHAPERONE MEDIATED AUTOPHAGY	20	2.13e-01	-1.61e-01	5.92e-01
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	81	2.13e-01	-8.00e-02	5.92e-01
REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	48	2.14e-01	1.04e-01	5.93e-01
REACTOME MAPK6 MAPK4 SIGNALING	91	2.15e-01	-7.53e-02	5.93e-01
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION	138	2.16e-01	-6.11e-02	5.95e-01
REACTOME TCR SIGNALING	113	2.16e-01	-6.73e-02	5.96e-01
REACTOME REGULATION OF PTEN LOCALIZATION	8	2.17e-01	-2.52e-01	5.96e-01
REACTOME LYSOSOME VESICLE BIOGENESIS	33	2.17e-01	-1.24e-01	5.96e-01
REACTOME G PROTEIN ACTIVATION	24	2.19e-01	-1.45e-01	5.98e-01
REACTOME PEPTIDE HORMONE BIOSYNTHESIS	13	2.19e-01	1.97e-01	5.98e-01
REACTOME ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS	41	2.19e-01	-1.11e-01	5.98e-01
REACTOME DISORDERS OF TRANSMEMBRANE TRANSPORTERS	170	2.20e-01	-5.46e-02	5.99e-01
REACTOME METABOLISM OF LIPIDS	709	2.20e-01	2.70e-02	5.99e-01
REACTOME PCP CE PATHWAY	91	2.20e-01	-7.43e-02	5.99e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1	31	2.21e-01	-1.27e-01	6.00e-01
REACTOME EARLY PHASE OF HIV LIFE CYCLE	14	2.22e-01	-1.89e-01	6.00e-01
REACTOME TRNA PROCESSING IN THE NUCLEUS	58	2.23e-01	-9.26e-02	6.00e-01
REACTOME HEDGEHOG OFF STATE	111	2.23e-01	-6.69e-02	6.00e-01
REACTOME DOWNREGULATION OF ERBB2 SIGNALING	29	2.24e-01	-1.31e-01	6.00e-01
REACTOME SCAVENGING OF HEME FROM PLASMA	13	2.24e-01	-1.95e-01	6.00e-01
REACTOME PYRIMIDINE CATABOLISM	12	2.24e-01	-2.03e-01	6.00e-01
REACTOME ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING	9	2.24e-01	2.34e-01	6.00e-01
REACTOME AMINE LIGAND BINDING RECEPTORS	40	2.24e-01	-1.11e-01	6.00e-01
REACTOME SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL	25	2.25e-01	1.40e-01	6.00e-01
REACTOME METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES	33	2.25e-01	1.22e-01	6.00e-01
REACTOME SIGNALLING TO RAS	20	2.26e-01	-1.56e-01	6.03e-01
REACTOME HEME DEGRADATION	15	2.27e-01	1.80e-01	6.03e-01
REACTOME REGULATION OF NPAS4 GENE EXPRESSION	13	2.28e-01	1.93e-01	6.05e-01
REACTOME BETA DEFENSINS	27	2.29e-01	-1.34e-01	6.06e-01
REACTOME LGI ADAM INTERACTIONS	14	2.29e-01	-1.86e-01	6.06e-01
REACTOME RAS PROCESSING	22	2.29e-01	-1.48e-01	6.06e-01
REACTOME EPITHELIAL MESENCHYMAL TRANSITION EMT DURING GASTRULATION	7	2.30e-01	-2.62e-01	6.07e-01
REACTOME EPHB MEDIATED FORWARD SIGNALING	41	2.31e-01	-1.08e-01	6.07e-01
REACTOME P2Y RECEPTORS	9	2.31e-01	2.31e-01	6.07e-01
REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	89	2.31e-01	7.35e-02	6.07e-01
REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES	37	2.33e-01	1.13e-01	6.07e-01
REACTOME SIGNALING BY FGFR1 IN DISEASE	38	2.33e-01	-1.12e-01	6.07e-01
REACTOME STRIATED MUSCLE CONTRACTION	35	2.33e-01	1.16e-01	6.07e-01
REACTOME RHOBTB GTPASE CYCLE	34	2.33e-01	-1.18e-01	6.07e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE	8	2.33e-01	2.43e-01	6.07e-01
REACTOME PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING	5	2.33e-01	-3.08e-01	6.07e-01
REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS	27	2.35e-01	1.32e-01	6.09e-01
REACTOME EICOSANOID LIGAND BINDING RECEPTORS	14	2.35e-01	-1.83e-01	6.09e-01
REACTOME NICOTINAMIDE SALVAGING	19	2.36e-01	1.57e-01	6.09e-01
REACTOME PEROXISOMAL PROTEIN IMPORT	62	2.36e-01	-8.70e-02	6.09e-01
REACTOME NECTIN NECL TRANS HETERODIMERIZATION	7	2.36e-01	-2.59e-01	6.09e-01
REACTOME RHOC GTPASE CYCLE	71	2.37e-01	8.12e-02	6.09e-01
REACTOME GABA RECEPTOR ACTIVATION	57	2.37e-01	-9.06e-02	6.09e-01
REACTOME ORGANIC ANION TRANSPORT	5	2.37e-01	3.05e-01	6.09e-01
REACTOME HIV TRANSCRIPTION INITIATION	43	2.38e-01	-1.04e-01	6.11e-01
REACTOME RNA POLYMERASE II TRANSCRIBES SNRNA GENES	77	2.39e-01	-7.75e-02	6.13e-01
REACTOME GENERATION OF SECOND MESSENGER MOLECULES	30	2.40e-01	1.24e-01	6.15e-01
REACTOME NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10	12	2.42e-01	-1.95e-01	6.18e-01
REACTOME SHC RELATED EVENTS TRIGGERED BY IGF1R	9	2.43e-01	-2.25e-01	6.20e-01
REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	15	2.44e-01	1.74e-01	6.20e-01
REACTOME RA BIOSYNTHESIS PATHWAY	22	2.44e-01	-1.43e-01	6.21e-01
REACTOME ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY	5	2.45e-01	-3.00e-01	6.21e-01
REACTOME RECYCLING PATHWAY OF L1	43	2.45e-01	-1.02e-01	6.21e-01
REACTOME DEGRADATION OF AXIN	54	2.45e-01	-9.14e-02	6.21e-01
REACTOME G ALPHA S SIGNALLING EVENTS	155	2.46e-01	-5.40e-02	6.22e-01
REACTOME SIGNALING BY NTRK2 TRKB	25	2.47e-01	-1.34e-01	6.22e-01
REACTOME RUNX2 REGULATES BONE DEVELOPMENT	29	2.47e-01	-1.24e-01	6.22e-01
REACTOME HEMOSTASIS	591	2.48e-01	-2.78e-02	6.22e-01
REACTOME SIGNALING BY VEGF	102	2.48e-01	6.62e-02	6.22e-01
REACTOME DUAL INCISION IN GG NER	39	2.48e-01	-1.07e-01	6.22e-01
REACTOME FREE FATTY ACIDS REGULATE INSULIN SECRETION	10	2.48e-01	2.11e-01	6.22e-01
REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX	13	2.50e-01	-1.84e-01	6.24e-01
REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION	35	2.51e-01	-1.12e-01	6.24e-01
REACTOME SIGNALING BY HIPPO	19	2.51e-01	-1.52e-01	6.24e-01
REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL	12	2.51e-01	-1.91e-01	6.24e-01
REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION	32	2.51e-01	-1.17e-01	6.24e-01
REACTOME SHC MEDIATED CASCADE FGFR3	17	2.52e-01	-1.61e-01	6.24e-01
REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	13	2.53e-01	1.83e-01	6.27e-01
REACTOME MRNA SPLICING MINOR PATHWAY	49	2.54e-01	-9.41e-02	6.28e-01
REACTOME SIGNALING BY MAPK MUTANTS	6	2.55e-01	-2.69e-01	6.28e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX3	94	2.55e-01	-6.79e-02	6.28e-01
REACTOME RHO GTPASE EFFECTORS	305	2.55e-01	-3.79e-02	6.28e-01
REACTOME SENSORY PROCESSING OF SOUND	72	2.56e-01	7.73e-02	6.30e-01
REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	38	2.57e-01	-1.06e-01	6.30e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3	11	2.57e-01	-1.97e-01	6.30e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR3	24	2.58e-01	-1.33e-01	6.31e-01
REACTOME TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX	14	2.59e-01	-1.74e-01	6.31e-01
REACTOME GLYCOGEN SYNTHESIS	13	2.59e-01	-1.81e-01	6.31e-01
REACTOME NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS	11	2.59e-01	-1.96e-01	6.31e-01
REACTOME RHOB GTPASE CYCLE	67	2.59e-01	7.97e-02	6.31e-01
REACTOME FGFR2 ALTERNATIVE SPLICING	27	2.61e-01	-1.25e-01	6.33e-01
REACTOME RAF INDEPENDENT MAPK1 3 ACTIVATION	22	2.61e-01	-1.38e-01	6.33e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES	10	2.61e-01	-2.05e-01	6.33e-01
REACTOME COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING	38	2.62e-01	-1.05e-01	6.34e-01
REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	296	2.64e-01	-3.77e-02	6.37e-01
REACTOME NEUROTRANSMITTER RELEASE CYCLE	48	2.65e-01	-9.31e-02	6.37e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR2	29	2.65e-01	-1.20e-01	6.37e-01
REACTOME TP53 REGULATES METABOLIC GENES	81	2.65e-01	-7.16e-02	6.37e-01
REACTOME GERM LAYER FORMATION AT GASTRULATION	17	2.67e-01	-1.56e-01	6.39e-01
REACTOME NEUROTRANSMITTER CLEARANCE	9	2.67e-01	2.14e-01	6.39e-01
REACTOME REGULATION OF BETA CELL DEVELOPMENT	41	2.67e-01	-1.00e-01	6.40e-01
REACTOME HDR THROUGH MMEJ ALT NHEJ	12	2.68e-01	-1.85e-01	6.40e-01
REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	7	2.68e-01	2.42e-01	6.40e-01
REACTOME GLYCOGEN STORAGE DISEASES	15	2.69e-01	-1.65e-01	6.40e-01
REACTOME UPTAKE OF DIETARY COBALAMINS INTO ENTEROCYTES	9	2.69e-01	2.13e-01	6.40e-01
REACTOME ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION	28	2.69e-01	-1.21e-01	6.40e-01
REACTOME TYSND1 CLEAVES PEROXISOMAL PROTEINS	7	2.71e-01	2.40e-01	6.40e-01
REACTOME REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS	11	2.71e-01	1.92e-01	6.40e-01
REACTOME INTEGRATION OF ENERGY METABOLISM	105	2.71e-01	6.21e-02	6.40e-01
REACTOME IRS ACTIVATION	5	2.72e-01	2.84e-01	6.40e-01
REACTOME RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX	29	2.72e-01	-1.18e-01	6.40e-01
REACTOME CA DEPENDENT EVENTS	36	2.72e-01	1.06e-01	6.40e-01
REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	62	2.72e-01	8.06e-02	6.40e-01
REACTOME SIGNALING BY ALK	26	2.73e-01	-1.24e-01	6.40e-01
REACTOME ATTENUATION PHASE	27	2.73e-01	-1.22e-01	6.40e-01
REACTOME TRAFFICKING OF AMPA RECEPTORS	29	2.74e-01	1.17e-01	6.40e-01
REACTOME AUTOPHAGY	144	2.74e-01	-5.28e-02	6.40e-01
REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	9	2.75e-01	2.10e-01	6.40e-01
REACTOME VESICLE MEDIATED TRANSPORT	642	2.75e-01	-2.53e-02	6.40e-01
REACTOME INTERLEUKIN 12 SIGNALING	43	2.75e-01	-9.62e-02	6.40e-01
REACTOME HOST INTERACTIONS OF HIV FACTORS	127	2.75e-01	-5.61e-02	6.40e-01
REACTOME IRE1ALPHA ACTIVATES CHAPERONES	48	2.77e-01	9.08e-02	6.42e-01
REACTOME PD 1 SIGNALING	21	2.77e-01	1.37e-01	6.42e-01
REACTOME REGULATION OF MECP2 EXPRESSION AND ACTIVITY	30	2.77e-01	1.15e-01	6.42e-01
REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS	42	2.79e-01	-9.65e-02	6.43e-01
REACTOME DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE	17	2.79e-01	1.52e-01	6.43e-01
REACTOME FGFR3 LIGAND BINDING AND ACTIVATION	12	2.80e-01	-1.80e-01	6.43e-01
REACTOME PROCESSING AND ACTIVATION OF SUMO	10	2.80e-01	-1.97e-01	6.43e-01
REACTOME REGULATION OF KIT SIGNALING	16	2.80e-01	-1.56e-01	6.43e-01
REACTOME NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS	25	2.80e-01	-1.25e-01	6.43e-01
REACTOME RND2 GTPASE CYCLE	42	2.81e-01	9.62e-02	6.43e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS	14	2.82e-01	1.66e-01	6.43e-01
REACTOME DARPP 32 EVENTS	24	2.82e-01	-1.27e-01	6.43e-01
REACTOME DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1	9	2.82e-01	-2.07e-01	6.43e-01
REACTOME INITIAL TRIGGERING OF COMPLEMENT	21	2.82e-01	1.36e-01	6.43e-01
REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS	19	2.82e-01	-1.42e-01	6.43e-01
REACTOME PLATELET CALCIUM HOMEOSTASIS	27	2.87e-01	1.18e-01	6.52e-01
REACTOME RHO GTPASES ACTIVATE CIT	19	2.87e-01	1.41e-01	6.52e-01
REACTOME REPRESSION OF WNT TARGET GENES	14	2.89e-01	1.64e-01	6.54e-01
REACTOME ACTIVATION OF AMPK DOWNSTREAM OF NMDARS	28	2.89e-01	-1.16e-01	6.54e-01
REACTOME DEFECTIVE EXT2 CAUSES EXOSTOSES 2	12	2.90e-01	1.76e-01	6.57e-01
REACTOME VLDLR INTERNALISATION AND DEGRADATION	16	2.91e-01	-1.52e-01	6.58e-01
REACTOME TRANSLESION SYNTHESIS BY POLK	17	2.94e-01	-1.47e-01	6.60e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY DVL INTERACTING PROTEINS	5	2.94e-01	2.71e-01	6.60e-01
REACTOME INTEGRIN CELL SURFACE INTERACTIONS	83	2.94e-01	6.66e-02	6.60e-01
REACTOME MITOPHAGY	28	2.94e-01	-1.15e-01	6.60e-01
REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS	6	2.95e-01	-2.47e-01	6.60e-01
REACTOME DOWNREGULATION OF ERBB4 SIGNALING	9	2.95e-01	-2.02e-01	6.60e-01
REACTOME TRAF6 MEDIATED NF KB ACTIVATION	24	2.97e-01	-1.23e-01	6.63e-01
REACTOME SYNTHESIS OF 12 EICOSATETRAENOIC ACID DERIVATIVES	7	3.02e-01	-2.25e-01	6.74e-01
REACTOME SIGNALING BY ERBB2	50	3.02e-01	-8.43e-02	6.74e-01
REACTOME P75NTR SIGNALS VIA NF KB	15	3.03e-01	-1.54e-01	6.74e-01
REACTOME FATTY ACIDS	15	3.03e-01	-1.54e-01	6.74e-01
REACTOME NUCLEOTIDE SALVAGE	21	3.05e-01	-1.29e-01	6.74e-01
REACTOME RHOV GTPASE CYCLE	36	3.05e-01	9.88e-02	6.74e-01
REACTOME PRE NOTCH PROCESSING IN GOLGI	18	3.05e-01	1.40e-01	6.74e-01
REACTOME RAB GERANYLGERANYLATION	57	3.05e-01	-7.85e-02	6.74e-01
REACTOME PKA ACTIVATION IN GLUCAGON SIGNALLING	17	3.05e-01	1.44e-01	6.74e-01
REACTOME APOPTOTIC FACTOR MEDIATED RESPONSE	19	3.06e-01	-1.36e-01	6.74e-01
REACTOME FOLDING OF ACTIN BY CCT TRIC	10	3.06e-01	-1.87e-01	6.74e-01
REACTOME VLDL CLEARANCE	6	3.07e-01	-2.41e-01	6.76e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS	8	3.08e-01	2.08e-01	6.76e-01
REACTOME NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS	22	3.09e-01	-1.25e-01	6.76e-01
REACTOME ARMS MEDIATED ACTIVATION	7	3.09e-01	-2.22e-01	6.76e-01
REACTOME CREATION OF C4 AND C2 ACTIVATORS	14	3.10e-01	1.57e-01	6.77e-01
REACTOME ESTABLISHMENT OF SISTER CHROMATID COHESION	9	3.10e-01	-1.96e-01	6.77e-01
REACTOME SUMO IS PROTEOLYTICALLY PROCESSED	6	3.11e-01	-2.39e-01	6.78e-01
REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III	31	3.11e-01	-1.05e-01	6.78e-01
REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE	9	3.12e-01	-1.95e-01	6.78e-01
REACTOME P38MAPK EVENTS	13	3.12e-01	-1.62e-01	6.79e-01
REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	21	3.13e-01	-1.27e-01	6.80e-01
REACTOME POST TRANSCRIPTIONAL SILENCING BY SMALL RNAS	7	3.14e-01	2.20e-01	6.80e-01
REACTOME NEF MEDIATED CD4 DOWN REGULATION	9	3.14e-01	1.94e-01	6.80e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES	16	3.15e-01	-1.45e-01	6.80e-01
REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	19	3.15e-01	1.33e-01	6.80e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS	7	3.16e-01	2.19e-01	6.80e-01
REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	18	3.16e-01	1.37e-01	6.80e-01
REACTOME INTERLEUKIN 37 SIGNALING	20	3.16e-01	-1.30e-01	6.80e-01
REACTOME INTERFERON SIGNALING	193	3.17e-01	-4.18e-02	6.80e-01
REACTOME AZATHIOPRINE ADME	22	3.17e-01	1.23e-01	6.80e-01
REACTOME KEAP1 NFE2L2 PATHWAY	104	3.17e-01	-5.67e-02	6.80e-01
REACTOME FGFR2B LIGAND BINDING AND ACTIVATION	10	3.18e-01	-1.83e-01	6.80e-01
REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	22	3.18e-01	1.23e-01	6.81e-01
REACTOME ELASTIC FIBRE FORMATION	44	3.19e-01	8.69e-02	6.81e-01
REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV 1 INFECTION	5	3.25e-01	-2.54e-01	6.92e-01
REACTOME GLYCOLYSIS	70	3.26e-01	6.79e-02	6.92e-01
REACTOME FATTY ACIDS BOUND TO GPR40 FFAR1 REGULATE INSULIN SECRETION	8	3.27e-01	2.00e-01	6.92e-01
REACTOME BINDING OF TCF LEF CTNNB1 TO TARGET GENE PROMOTERS	8	3.27e-01	2.00e-01	6.92e-01
REACTOME PURINE CATABOLISM	17	3.27e-01	-1.37e-01	6.92e-01
REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	24	3.27e-01	1.16e-01	6.92e-01
REACTOME ERYTHROPOIETIN ACTIVATES RAS	14	3.27e-01	-1.51e-01	6.92e-01
REACTOME SIGNALING BY FGFR2 IN DISEASE	42	3.28e-01	-8.72e-02	6.93e-01
REACTOME RHOH GTPASE CYCLE	37	3.28e-01	-9.28e-02	6.93e-01
REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES	77	3.31e-01	-6.41e-02	6.97e-01
REACTOME OVARIAN TUMOR DOMAIN PROTEASES	36	3.31e-01	-9.36e-02	6.97e-01
REACTOME PERK REGULATES GENE EXPRESSION	31	3.32e-01	-1.01e-01	6.97e-01
REACTOME SIGNALING BY NOTCH1	69	3.32e-01	-6.75e-02	6.97e-01
REACTOME PI 3K CASCADE FGFR4	19	3.33e-01	-1.28e-01	6.97e-01
REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK	17	3.33e-01	-1.36e-01	6.97e-01
REACTOME PROTEIN METHYLATION	17	3.33e-01	-1.36e-01	6.97e-01
REACTOME SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS	12	3.35e-01	-1.61e-01	7.00e-01
REACTOME SODIUM COUPLED PHOSPHATE COTRANSPORTERS	5	3.36e-01	2.48e-01	7.01e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA	27	3.37e-01	-1.07e-01	7.03e-01
REACTOME TNF SIGNALING	54	3.40e-01	-7.51e-02	7.06e-01
REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	12	3.40e-01	-1.59e-01	7.06e-01
REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES	34	3.41e-01	-9.44e-02	7.07e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS	6	3.41e-01	-2.25e-01	7.07e-01
REACTOME RHOA GTPASE CYCLE	142	3.43e-01	4.61e-02	7.08e-01
REACTOME POLB DEPENDENT LONG PATCH BASE EXCISION REPAIR	8	3.44e-01	1.93e-01	7.08e-01
REACTOME INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE	20	3.44e-01	1.22e-01	7.08e-01
REACTOME MEMBRANE TRAFFICKING	603	3.45e-01	-2.25e-02	7.08e-01
REACTOME RHO GTPASES ACTIVATE NADPH OXIDASES	21	3.45e-01	-1.19e-01	7.08e-01
REACTOME ANTIMICROBIAL PEPTIDES	76	3.45e-01	-6.26e-02	7.08e-01
REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	78	3.46e-01	-6.18e-02	7.08e-01
REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION	62	3.46e-01	-6.92e-02	7.08e-01
REACTOME PHASE 1 INACTIVATION OF FAST NA CHANNELS	6	3.46e-01	-2.22e-01	7.08e-01
REACTOME GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION	42	3.47e-01	-8.39e-02	7.08e-01
REACTOME RORA ACTIVATES GENE EXPRESSION	17	3.47e-01	1.32e-01	7.08e-01
REACTOME RAF ACTIVATION	33	3.47e-01	9.47e-02	7.08e-01
REACTOME CROSSLINKING OF COLLAGEN FIBRILS	16	3.48e-01	1.36e-01	7.09e-01
REACTOME EXTRA NUCLEAR ESTROGEN SIGNALING	74	3.48e-01	-6.31e-02	7.09e-01
REACTOME ACYL CHAIN REMODELLING OF PI	17	3.49e-01	1.31e-01	7.09e-01
REACTOME CD163 MEDIATING AN ANTI INFLAMMATORY RESPONSE	9	3.49e-01	-1.80e-01	7.10e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	14	3.50e-01	1.44e-01	7.10e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST	14	3.50e-01	-1.44e-01	7.10e-01
REACTOME INTERLEUKIN RECEPTOR SHC SIGNALING	24	3.53e-01	-1.10e-01	7.14e-01
REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	15	3.53e-01	-1.39e-01	7.14e-01
REACTOME IRAK4 DEFICIENCY TLR2 4	17	3.54e-01	-1.30e-01	7.14e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE	5	3.54e-01	-2.39e-01	7.14e-01
REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	35	3.55e-01	-9.04e-02	7.14e-01
REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	30	3.55e-01	-9.76e-02	7.14e-01
REACTOME ALPHA DEFENSINS	6	3.55e-01	2.18e-01	7.14e-01
REACTOME DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX	83	3.56e-01	-5.86e-02	7.14e-01
REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	31	3.57e-01	-9.56e-02	7.14e-01
REACTOME TRANSCRIPTION OF THE HIV GENOME	66	3.57e-01	-6.55e-02	7.14e-01
REACTOME PLATELET SENSITIZATION BY LDL	17	3.58e-01	-1.29e-01	7.14e-01
REACTOME EARLY SARS COV 2 INFECTION EVENTS	34	3.58e-01	-9.11e-02	7.14e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION TERMINATION	30	3.59e-01	-9.69e-02	7.14e-01
REACTOME CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS	100	3.59e-01	-5.31e-02	7.14e-01
REACTOME DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS	25	3.60e-01	-1.06e-01	7.14e-01
REACTOME DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A	5	3.61e-01	2.36e-01	7.14e-01
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION	1356	3.61e-01	-1.48e-02	7.14e-01
REACTOME MICRORNA MIRNA BIOGENESIS	25	3.61e-01	1.06e-01	7.14e-01
REACTOME G0 AND EARLY G1	27	3.62e-01	-1.01e-01	7.14e-01
REACTOME REDUCTION OF CYTOSOLIC CA LEVELS	11	3.62e-01	1.59e-01	7.14e-01
REACTOME SIGNALING BY ERYTHROPOIETIN	25	3.63e-01	-1.05e-01	7.14e-01
REACTOME PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS	21	3.63e-01	-1.15e-01	7.14e-01
REACTOME SIGNALING BY BMP	27	3.63e-01	-1.01e-01	7.14e-01
REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION	6	3.63e-01	-2.14e-01	7.14e-01
REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	19	3.63e-01	-1.20e-01	7.14e-01
REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS	17	3.65e-01	1.27e-01	7.17e-01
REACTOME SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER	54	3.67e-01	-7.10e-02	7.20e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER	28	3.67e-01	-9.84e-02	7.20e-01
REACTOME ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING	23	3.68e-01	-1.08e-01	7.20e-01
REACTOME EPH EPHRIN SIGNALING	90	3.68e-01	-5.49e-02	7.20e-01
REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	10	3.70e-01	1.64e-01	7.20e-01
REACTOME EPHA MEDIATED GROWTH CONE COLLAPSE	29	3.70e-01	-9.62e-02	7.20e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH CDK5	6	3.70e-01	-2.11e-01	7.20e-01
REACTOME TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION	5	3.70e-01	-2.31e-01	7.20e-01
REACTOME ION HOMEOSTASIS	52	3.73e-01	7.14e-02	7.25e-01
REACTOME BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA	6	3.73e-01	2.10e-01	7.25e-01
REACTOME DNA DOUBLE STRAND BREAK RESPONSE	74	3.74e-01	-5.98e-02	7.25e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL	15	3.75e-01	1.32e-01	7.27e-01
REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	12	3.76e-01	-1.48e-01	7.28e-01
REACTOME FGFR3B LIGAND BINDING AND ACTIVATION	7	3.78e-01	-1.92e-01	7.30e-01
REACTOME NRCAM INTERACTIONS	6	3.78e-01	2.08e-01	7.30e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	27	3.79e-01	9.78e-02	7.30e-01
REACTOME SIGNALING BY GPCR	673	3.80e-01	-1.99e-02	7.30e-01
REACTOME METABOLISM OF NUCLEOTIDES	94	3.80e-01	-5.24e-02	7.30e-01
REACTOME COSTIMULATION BY THE CD28 FAMILY	64	3.81e-01	6.33e-02	7.32e-01
REACTOME ERYTHROPOIETIN ACTIVATES STAT5	7	3.82e-01	-1.91e-01	7.32e-01
REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	69	3.82e-01	6.08e-02	7.32e-01
REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	11	3.84e-01	1.52e-01	7.35e-01
REACTOME RHO GTPASES ACTIVATE PAKS	19	3.85e-01	1.15e-01	7.35e-01
REACTOME UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION	19	3.85e-01	-1.15e-01	7.35e-01
REACTOME REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE	81	3.86e-01	-5.58e-02	7.35e-01
REACTOME LEISHMANIA INFECTION	156	3.86e-01	-4.02e-02	7.36e-01
REACTOME FCERI MEDIATED MAPK ACTIVATION	32	3.87e-01	-8.84e-02	7.36e-01
REACTOME SYNTHESIS OF PG	8	3.87e-01	1.76e-01	7.36e-01
REACTOME DIGESTION OF DIETARY LIPID	7	3.88e-01	1.88e-01	7.36e-01
REACTOME UPTAKE AND FUNCTION OF ANTHRAX TOXINS	11	3.89e-01	1.50e-01	7.36e-01
REACTOME REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION	9	3.89e-01	-1.66e-01	7.36e-01
REACTOME BETA CATENIN INDEPENDENT WNT SIGNALING	145	3.89e-01	-4.15e-02	7.36e-01
REACTOME FRS MEDIATED FGFR3 SIGNALING	19	3.90e-01	-1.14e-01	7.36e-01
REACTOME TNFR1 INDUCED PROAPOPTOTIC SIGNALING	23	3.90e-01	-1.03e-01	7.36e-01
REACTOME IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN	5	3.90e-01	2.22e-01	7.36e-01
REACTOME FRS MEDIATED FGFR2 SIGNALING	24	3.91e-01	-1.01e-01	7.36e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS	5	3.92e-01	-2.21e-01	7.37e-01
REACTOME RAC1 GTPASE CYCLE	172	3.92e-01	3.78e-02	7.37e-01
REACTOME RHOG GTPASE CYCLE	71	3.94e-01	5.85e-02	7.39e-01
REACTOME BIOTIN TRANSPORT AND METABOLISM	10	3.95e-01	1.55e-01	7.39e-01
REACTOME INDUCTION OF CELL CELL FUSION	12	3.95e-01	-1.42e-01	7.39e-01
REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	44	4.00e-01	-7.34e-02	7.47e-01
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION	250	4.00e-01	-3.09e-02	7.47e-01
REACTOME PYRUVATE METABOLISM	29	4.00e-01	9.03e-02	7.47e-01
REACTOME RNA POLYMERASE II PRE TRANSCRIPTION EVENTS	77	4.04e-01	-5.51e-02	7.51e-01
REACTOME PHASE II CONJUGATION OF COMPOUNDS	102	4.04e-01	-4.79e-02	7.51e-01
REACTOME CARNITINE METABOLISM	13	4.04e-01	1.34e-01	7.52e-01
REACTOME REGULATED PROTEOLYSIS OF P75NTR	11	4.05e-01	-1.45e-01	7.52e-01
REACTOME SIGNALING BY PDGF	57	4.06e-01	-6.36e-02	7.54e-01
REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS	6	4.08e-01	1.95e-01	7.57e-01
REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	24	4.11e-01	-9.70e-02	7.60e-01
REACTOME RELEASE OF HH NP FROM THE SECRETING CELL	8	4.11e-01	-1.68e-01	7.60e-01
REACTOME PEXOPHAGY	11	4.13e-01	-1.43e-01	7.61e-01
REACTOME MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS	13	4.14e-01	-1.31e-01	7.61e-01
REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS	8	4.14e-01	1.67e-01	7.61e-01
REACTOME RHOQ GTPASE CYCLE	57	4.14e-01	6.25e-02	7.61e-01
REACTOME GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION	7	4.14e-01	-1.78e-01	7.61e-01
REACTOME SUPPRESSION OF PHAGOSOMAL MATURATION	13	4.14e-01	-1.31e-01	7.61e-01
REACTOME OTHER INTERLEUKIN SIGNALING	24	4.16e-01	9.59e-02	7.61e-01
REACTOME METABOLISM OF STEROIDS	150	4.16e-01	3.85e-02	7.61e-01
REACTOME TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS	55	4.16e-01	6.33e-02	7.61e-01
REACTOME CS DS DEGRADATION	12	4.17e-01	1.35e-01	7.61e-01
REACTOME BUDDING AND MATURATION OF HIV VIRION	28	4.17e-01	-8.86e-02	7.61e-01
REACTOME ORGANIC ANION TRANSPORTERS	10	4.17e-01	1.48e-01	7.61e-01
REACTOME SENSING OF DNA DOUBLE STRAND BREAKS	6	4.19e-01	-1.91e-01	7.63e-01
REACTOME TRYPTOPHAN CATABOLISM	14	4.19e-01	1.25e-01	7.63e-01
REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	16	4.20e-01	1.16e-01	7.64e-01
REACTOME SUMOYLATION OF RNA BINDING PROTEINS	47	4.21e-01	-6.79e-02	7.64e-01
REACTOME ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE	9	4.21e-01	-1.55e-01	7.64e-01
REACTOME TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS	52	4.21e-01	-6.44e-02	7.64e-01
REACTOME SIALIC ACID METABOLISM	33	4.22e-01	8.08e-02	7.64e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	14	4.23e-01	1.24e-01	7.64e-01
REACTOME RHOBTB2 GTPASE CYCLE	22	4.23e-01	-9.86e-02	7.64e-01
REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET	8	4.24e-01	-1.63e-01	7.64e-01
REACTOME ACTIVATION OF BH3 ONLY PROTEINS	30	4.25e-01	8.42e-02	7.66e-01
REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	35	4.27e-01	-7.76e-02	7.67e-01
REACTOME SIGNALING BY FGFR IN DISEASE	62	4.27e-01	-5.84e-02	7.67e-01
REACTOME SIGNALING BY NOTCH1 T 7 9 NOTCH1 M1580 K2555 TRANSLOCATION MUTANT	7	4.27e-01	1.73e-01	7.67e-01
REACTOME GLUCOCORTICOID BIOSYNTHESIS	10	4.29e-01	-1.45e-01	7.68e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES	33	4.29e-01	-7.96e-02	7.68e-01
REACTOME INWARDLY RECTIFYING K CHANNELS	35	4.29e-01	-7.72e-02	7.68e-01
REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC	198	4.29e-01	-3.26e-02	7.68e-01
REACTOME SMALL INTERFERING RNA SIRNA BIOGENESIS	9	4.30e-01	1.52e-01	7.69e-01
REACTOME INTERLEUKIN 20 FAMILY SIGNALING	25	4.31e-01	-9.09e-02	7.69e-01
REACTOME NICOTINATE METABOLISM	31	4.32e-01	8.16e-02	7.69e-01
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES	255	4.32e-01	-2.86e-02	7.69e-01
REACTOME SEMA4D IN SEMAPHORIN SIGNALING	24	4.33e-01	9.25e-02	7.70e-01
REACTOME RHO GTPASES ACTIVATE ROCKS	19	4.34e-01	1.04e-01	7.70e-01
REACTOME NONHOMOLOGOUS END JOINING NHEJ	64	4.35e-01	-5.65e-02	7.71e-01
REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	36	4.35e-01	-7.51e-02	7.71e-01
REACTOME MHC CLASS II ANTIGEN PRESENTATION	121	4.35e-01	-4.10e-02	7.71e-01
REACTOME GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	34	4.36e-01	7.73e-02	7.71e-01
REACTOME RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS	9	4.38e-01	1.49e-01	7.75e-01
REACTOME REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR	11	4.39e-01	1.35e-01	7.75e-01
REACTOME CD22 MEDIATED BCR REGULATION	5	4.40e-01	-1.99e-01	7.76e-01
REACTOME SIGNALING BY MST1	5	4.40e-01	1.99e-01	7.76e-01
REACTOME TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS	36	4.41e-01	7.42e-02	7.77e-01
REACTOME OPIOID SIGNALLING	89	4.44e-01	-4.70e-02	7.80e-01
REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	46	4.45e-01	-6.51e-02	7.81e-01
REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	15	4.46e-01	1.14e-01	7.82e-01
REACTOME COMPLEX I BIOGENESIS	49	4.46e-01	-6.29e-02	7.82e-01
REACTOME CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION	24	4.48e-01	-8.95e-02	7.82e-01
REACTOME CD28 DEPENDENT VAV1 PATHWAY	11	4.48e-01	-1.32e-01	7.82e-01
REACTOME REGULATION OF RUNX3 EXPRESSION AND ACTIVITY	54	4.49e-01	-5.95e-02	7.82e-01
REACTOME ANCHORING FIBRIL FORMATION	13	4.50e-01	1.21e-01	7.82e-01
REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	20	4.50e-01	-9.77e-02	7.82e-01
REACTOME REGULATION OF PTEN STABILITY AND ACTIVITY	67	4.50e-01	-5.34e-02	7.82e-01
REACTOME SPERM MOTILITY AND TAXES	9	4.50e-01	1.45e-01	7.82e-01
REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	37	4.52e-01	-7.15e-02	7.82e-01
REACTOME TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY	30	4.52e-01	-7.94e-02	7.82e-01
REACTOME PHENYLALANINE AND TYROSINE METABOLISM	11	4.52e-01	1.31e-01	7.82e-01
REACTOME NFE2L2 REGULATING ANTI OXIDANT DETOXIFICATION ENZYMES	17	4.53e-01	1.05e-01	7.82e-01
REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL	41	4.53e-01	-6.77e-02	7.82e-01
REACTOME IRF3 MEDIATED INDUCTION OF TYPE I IFN	13	4.53e-01	-1.20e-01	7.82e-01
REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	28	4.53e-01	8.18e-02	7.82e-01
REACTOME ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY	10	4.54e-01	1.37e-01	7.82e-01
REACTOME INTERLEUKIN 36 PATHWAY	7	4.54e-01	1.63e-01	7.82e-01
REACTOME CIRCADIAN CLOCK	68	4.54e-01	-5.25e-02	7.82e-01
REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING	6	4.56e-01	-1.76e-01	7.83e-01
REACTOME EGFR TRANSACTIVATION BY GASTRIN	9	4.56e-01	-1.44e-01	7.83e-01
REACTOME COBALAMIN CBL METABOLISM	7	4.58e-01	-1.62e-01	7.85e-01
REACTOME ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS	11	4.59e-01	1.29e-01	7.86e-01
REACTOME OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS	8	4.59e-01	1.51e-01	7.86e-01
REACTOME NUCLEOTIDE EXCISION REPAIR	107	4.60e-01	-4.13e-02	7.87e-01
REACTOME G ALPHA Z SIGNALLING EVENTS	48	4.62e-01	-6.14e-02	7.88e-01
REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	12	4.62e-01	-1.23e-01	7.88e-01
REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS	5	4.62e-01	1.90e-01	7.88e-01
REACTOME UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN	6	4.63e-01	-1.73e-01	7.88e-01
REACTOME INTERFERON ALPHA BETA SIGNALING	70	4.63e-01	-5.07e-02	7.88e-01
REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL	58	4.64e-01	-5.56e-02	7.89e-01
REACTOME GAP JUNCTION DEGRADATION	12	4.68e-01	-1.21e-01	7.93e-01
REACTOME SEROTONIN NEUROTRANSMITTER RELEASE CYCLE	17	4.68e-01	-1.02e-01	7.93e-01
REACTOME MAPK3 ERK1 ACTIVATION	10	4.68e-01	-1.32e-01	7.93e-01
REACTOME CONSTITUTIVE SIGNALING BY EGFRVIII	15	4.68e-01	-1.08e-01	7.93e-01
REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION	23	4.70e-01	-8.70e-02	7.95e-01
REACTOME MET ACTIVATES RAS SIGNALING	11	4.71e-01	-1.26e-01	7.95e-01
REACTOME REGULATION OF NPAS4 GENE TRANSCRIPTION	5	4.71e-01	1.86e-01	7.95e-01
REACTOME N GLYCAN ANTENNAE ELONGATION	15	4.71e-01	-1.07e-01	7.95e-01
REACTOME PHASE 3 RAPID REPOLARISATION	8	4.72e-01	1.47e-01	7.95e-01
REACTOME STAT3 NUCLEAR EVENTS DOWNSTREAM OF ALK SIGNALING	9	4.74e-01	-1.38e-01	7.97e-01
REACTOME PLATELET HOMEOSTASIS	85	4.74e-01	-4.49e-02	7.97e-01
REACTOME SIGNALING BY LRP5 MUTANTS	6	4.75e-01	-1.69e-01	7.97e-01
REACTOME INTRA GOLGI TRAFFIC	43	4.75e-01	-6.29e-02	7.97e-01
REACTOME REGULATION OF PTEN MRNA TRANSLATION	9	4.76e-01	1.37e-01	7.97e-01
REACTOME ACTIVATION OF MATRIX METALLOPROTEINASES	30	4.76e-01	7.51e-02	7.97e-01
REACTOME ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS	87	4.77e-01	-4.41e-02	7.98e-01
REACTOME GLUCOSE METABOLISM	90	4.79e-01	4.32e-02	7.99e-01
REACTOME PRE NOTCH EXPRESSION AND PROCESSING	112	4.79e-01	-3.87e-02	7.99e-01
REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	15	4.80e-01	1.05e-01	7.99e-01
REACTOME GLYCOSAMINOGLYCAN METABOLISM	118	4.80e-01	3.76e-02	7.99e-01
REACTOME KETONE BODY METABOLISM	9	4.81e-01	1.36e-01	7.99e-01
REACTOME SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX	15	4.82e-01	1.05e-01	7.99e-01
REACTOME CONJUGATION OF BENZOATE WITH GLYCINE	6	4.83e-01	1.65e-01	7.99e-01
REACTOME GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER	25	4.83e-01	-8.10e-02	7.99e-01
REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	29	4.83e-01	-7.52e-02	7.99e-01
REACTOME FORMATION OF APOPTOSOME	10	4.83e-01	-1.28e-01	7.99e-01
REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE	277	4.83e-01	-2.45e-02	7.99e-01
REACTOME METHYLATION	14	4.84e-01	-1.08e-01	8.00e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX	91	4.85e-01	4.23e-02	8.01e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES	11	4.86e-01	-1.21e-01	8.01e-01
REACTOME DEFENSINS	33	4.87e-01	-6.99e-02	8.02e-01
REACTOME MYOCLONIC EPILEPSY OF LAFORA	9	4.88e-01	-1.33e-01	8.03e-01
REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	15	4.88e-01	1.03e-01	8.03e-01
REACTOME DECTIN 2 FAMILY	26	4.90e-01	7.82e-02	8.05e-01
REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	11	4.92e-01	1.20e-01	8.06e-01
REACTOME GDP FUCOSE BIOSYNTHESIS	6	4.92e-01	1.62e-01	8.07e-01
REACTOME FBXW7 MUTANTS AND NOTCH1 IN CANCER	5	4.93e-01	-1.77e-01	8.07e-01
REACTOME METABOLISM OF STEROID HORMONES	35	4.93e-01	-6.69e-02	8.07e-01
REACTOME CLATHRIN MEDIATED ENDOCYTOSIS	139	4.94e-01	-3.36e-02	8.07e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR4	26	4.95e-01	-7.73e-02	8.08e-01
REACTOME XENOBIOTICS	22	4.95e-01	8.40e-02	8.08e-01
REACTOME POTASSIUM CHANNELS	102	4.97e-01	-3.89e-02	8.10e-01
REACTOME MATURATION OF SARS COV 1 SPIKE PROTEIN	5	4.98e-01	-1.75e-01	8.10e-01
REACTOME PHASE 2 PLATEAU PHASE	14	4.99e-01	1.04e-01	8.12e-01
REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL	13	5.00e-01	-1.08e-01	8.12e-01
REACTOME ABACAVIR TRANSMEMBRANE TRANSPORT	5	5.02e-01	1.74e-01	8.12e-01
REACTOME MISCELLANEOUS SUBSTRATES	12	5.02e-01	-1.12e-01	8.12e-01
REACTOME TRANSCRIPTIONAL REGULATION BY E2F6	32	5.02e-01	6.85e-02	8.12e-01
REACTOME CREB3 FACTORS ACTIVATE GENES	8	5.04e-01	-1.37e-01	8.12e-01
REACTOME ACYL CHAIN REMODELLING OF PG	18	5.04e-01	9.10e-02	8.12e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS	14	5.04e-01	1.03e-01	8.12e-01
REACTOME CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY	12	5.05e-01	1.11e-01	8.12e-01
REACTOME PROTON COUPLED MONOCARBOXYLATE TRANSPORT	6	5.05e-01	1.57e-01	8.12e-01
REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	45	5.06e-01	-5.74e-02	8.12e-01
REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	21	5.06e-01	-8.38e-02	8.12e-01
REACTOME DEFECTS IN BIOTIN BTN METABOLISM	8	5.06e-01	1.36e-01	8.12e-01
REACTOME G ALPHA Q SIGNALLING EVENTS	206	5.07e-01	-2.68e-02	8.12e-01
REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	11	5.07e-01	1.16e-01	8.12e-01
REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS	18	5.07e-01	-9.03e-02	8.12e-01
REACTOME SUMOYLATION OF IMMUNE RESPONSE PROTEINS	10	5.08e-01	1.21e-01	8.12e-01
REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	19	5.09e-01	-8.75e-02	8.12e-01
REACTOME NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION	20	5.09e-01	-8.53e-02	8.12e-01
REACTOME REGULATION OF PTEN GENE TRANSCRIPTION	59	5.09e-01	4.97e-02	8.12e-01
REACTOME REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION	84	5.10e-01	-4.15e-02	8.13e-01
REACTOME RESOLUTION OF SISTER CHROMATID COHESION	120	5.11e-01	-3.48e-02	8.13e-01
REACTOME MASTL FACILITATES MITOTIC PROGRESSION	10	5.12e-01	1.20e-01	8.15e-01
REACTOME G PROTEIN MEDIATED EVENTS	53	5.13e-01	5.19e-02	8.16e-01
REACTOME PECAM1 INTERACTIONS	12	5.15e-01	-1.09e-01	8.17e-01
REACTOME ACTIVATION OF TRKA RECEPTORS	6	5.16e-01	-1.53e-01	8.18e-01
REACTOME SULFIDE OXIDATION TO SULFATE	6	5.16e-01	1.53e-01	8.18e-01
REACTOME MUSCARINIC ACETYLCHOLINE RECEPTORS	5	5.17e-01	1.67e-01	8.18e-01
REACTOME INTEGRIN SIGNALING	27	5.18e-01	7.19e-02	8.19e-01
REACTOME IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS	17	5.18e-01	-9.05e-02	8.19e-01
REACTOME RHO GTPASES ACTIVATE WASPS AND WAVES	34	5.19e-01	-6.39e-02	8.20e-01
REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING	29	5.20e-01	-6.90e-02	8.20e-01
REACTOME HEME SIGNALING	47	5.21e-01	5.42e-02	8.20e-01
REACTOME PREVENTION OF PHAGOSOMAL LYSOSOMAL FUSION	9	5.23e-01	-1.23e-01	8.23e-01
REACTOME INFECTION WITH MYCOBACTERIUM TUBERCULOSIS	25	5.23e-01	-7.37e-02	8.23e-01
REACTOME TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS	82	5.26e-01	4.05e-02	8.24e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE	20	5.26e-01	8.19e-02	8.24e-01
REACTOME THYROXINE BIOSYNTHESIS	10	5.27e-01	1.16e-01	8.24e-01
REACTOME RHOU GTPASE CYCLE	37	5.27e-01	6.01e-02	8.24e-01
REACTOME GABA B RECEPTOR ACTIVATION	43	5.28e-01	-5.57e-02	8.24e-01
REACTOME ERK MAPK TARGETS	20	5.28e-01	-8.16e-02	8.24e-01
REACTOME RRNA MODIFICATION IN THE MITOCHONDRION	6	5.29e-01	1.49e-01	8.24e-01
REACTOME HATS ACETYLATE HISTONES	129	5.30e-01	-3.21e-02	8.24e-01
REACTOME RUNX2 REGULATES CHONDROCYTE MATURATION	5	5.30e-01	1.62e-01	8.24e-01
REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	16	5.30e-01	9.07e-02	8.24e-01
REACTOME TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA	36	5.30e-01	-6.05e-02	8.24e-01
REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM	50	5.30e-01	5.13e-02	8.24e-01
REACTOME PROLONGED ERK ACTIVATION EVENTS	14	5.30e-01	-9.68e-02	8.24e-01
REACTOME ACYL CHAIN REMODELING OF DAG AND TAG	5	5.33e-01	1.61e-01	8.27e-01
REACTOME BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA	5	5.34e-01	1.60e-01	8.28e-01
REACTOME L1CAM INTERACTIONS	112	5.35e-01	-3.40e-02	8.28e-01
REACTOME MET RECEPTOR ACTIVATION	6	5.35e-01	-1.46e-01	8.28e-01
REACTOME NEURONAL SYSTEM	388	5.36e-01	-1.83e-02	8.28e-01
REACTOME UBIQUINOL BIOSYNTHESIS	8	5.36e-01	-1.26e-01	8.28e-01
REACTOME POLO LIKE KINASE MEDIATED EVENTS	16	5.37e-01	-8.91e-02	8.29e-01
REACTOME SIGNALING BY NOTCH3	48	5.39e-01	-5.12e-02	8.30e-01
REACTOME SYNTHESIS OF LIPOXINS LX	6	5.40e-01	-1.45e-01	8.30e-01
REACTOME NUCLEAR ENVELOPE NE REASSEMBLY	74	5.40e-01	-4.12e-02	8.30e-01
REACTOME SUMO IS CONJUGATED TO E1 UBA2 SAE1	5	5.40e-01	-1.58e-01	8.30e-01
REACTOME TRIGLYCERIDE METABOLISM	35	5.41e-01	5.97e-02	8.30e-01
REACTOME SHC MEDIATED CASCADE FGFR4	19	5.41e-01	-8.09e-02	8.30e-01
REACTOME COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM	21	5.42e-01	7.69e-02	8.30e-01
REACTOME PARASITE INFECTION	57	5.42e-01	-4.67e-02	8.31e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS	9	5.43e-01	1.17e-01	8.31e-01
REACTOME PLATELET AGGREGATION PLUG FORMATION	39	5.44e-01	-5.61e-02	8.32e-01
REACTOME POLYMERASE SWITCHING	13	5.46e-01	-9.67e-02	8.34e-01
REACTOME HIV TRANSCRIPTION ELONGATION	42	5.49e-01	-5.35e-02	8.35e-01
REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3	679	5.49e-01	-1.35e-02	8.35e-01
REACTOME ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM	12	5.49e-01	9.98e-02	8.35e-01
REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	54	5.49e-01	-4.71e-02	8.35e-01
REACTOME CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION	11	5.50e-01	-1.04e-01	8.35e-01
REACTOME BIOLOGICAL OXIDATIONS	210	5.51e-01	-2.39e-02	8.35e-01
REACTOME RHO GTPASES ACTIVATE KTN1	11	5.51e-01	-1.04e-01	8.35e-01
REACTOME METABOLISM OF PORPHYRINS	26	5.52e-01	6.74e-02	8.35e-01
REACTOME CYTOCHROME C MEDIATED APOPTOTIC RESPONSE	12	5.52e-01	-9.92e-02	8.35e-01
REACTOME ACTIVATION OF C3 AND C5	6	5.53e-01	1.40e-01	8.35e-01
REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX	36	5.53e-01	5.71e-02	8.35e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES	49	5.54e-01	-4.89e-02	8.35e-01
REACTOME SYNTHESIS OF PI	5	5.54e-01	1.53e-01	8.35e-01
REACTOME G ALPHA I SIGNALLING EVENTS	304	5.54e-01	-1.97e-02	8.35e-01
REACTOME BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA	5	5.55e-01	1.53e-01	8.35e-01
REACTOME CREB PHOSPHORYLATION	6	5.55e-01	-1.39e-01	8.35e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS	15	5.56e-01	-8.78e-02	8.35e-01
REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	11	5.56e-01	1.02e-01	8.35e-01
REACTOME RMTS METHYLATE HISTONE ARGININES	72	5.57e-01	-4.01e-02	8.35e-01
REACTOME HDL REMODELING	10	5.57e-01	1.07e-01	8.35e-01
REACTOME DEFECTIVE CHST3 CAUSES SEDCJD	7	5.57e-01	1.28e-01	8.35e-01
REACTOME NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY	6	5.58e-01	1.38e-01	8.35e-01
REACTOME DISSOLUTION OF FIBRIN CLOT	13	5.58e-01	9.38e-02	8.35e-01
REACTOME LRR FLII INTERACTING PROTEIN 1 LRRFIP1 ACTIVATES TYPE I IFN PRODUCTION	5	5.59e-01	1.51e-01	8.35e-01
REACTOME METABOLISM OF COFACTORS	19	5.61e-01	-7.70e-02	8.35e-01
REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS	101	5.61e-01	-3.34e-02	8.35e-01
REACTOME SUMO IS TRANSFERRED FROM E1 TO E2 UBE2I UBC9	7	5.62e-01	-1.27e-01	8.35e-01
REACTOME VIRAL MESSENGER RNA SYNTHESIS	44	5.62e-01	-5.05e-02	8.35e-01
REACTOME NETRIN 1 SIGNALING	49	5.63e-01	-4.78e-02	8.35e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES	43	5.63e-01	-5.10e-02	8.35e-01
REACTOME BIOSYNTHESIS OF MARESINS	8	5.63e-01	1.18e-01	8.35e-01
REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	20	5.63e-01	7.47e-02	8.35e-01
REACTOME ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS	24	5.64e-01	6.80e-02	8.36e-01
REACTOME MITOTIC PROMETAPHASE	194	5.65e-01	-2.40e-02	8.36e-01
REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS	83	5.65e-01	-3.65e-02	8.36e-01
REACTOME NUCLEOTIDE BIOSYNTHESIS	14	5.66e-01	8.85e-02	8.37e-01
REACTOME METAL ION SLC TRANSPORTERS	23	5.68e-01	-6.88e-02	8.39e-01
REACTOME NEGATIVE REGULATION OF ACTIVITY OF TFAP2 AP 2 FAMILY TRANSCRIPTION FACTORS	10	5.69e-01	-1.04e-01	8.39e-01
REACTOME MRNA EDITING C TO U CONVERSION	8	5.69e-01	-1.16e-01	8.39e-01
REACTOME GPVI MEDIATED ACTIVATION CASCADE	35	5.71e-01	-5.53e-02	8.41e-01
REACTOME GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION	14	5.72e-01	-8.73e-02	8.41e-01
REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	14	5.72e-01	-8.72e-02	8.41e-01
REACTOME METABOLISM OF CARBOHYDRATES	279	5.74e-01	1.95e-02	8.43e-01
REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	16	5.75e-01	-8.10e-02	8.43e-01
REACTOME SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA	52	5.75e-01	4.50e-02	8.43e-01
REACTOME CHL1 INTERACTIONS	9	5.77e-01	-1.07e-01	8.43e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2	17	5.77e-01	-7.81e-02	8.43e-01
REACTOME RAS SIGNALING DOWNSTREAM OF NF1 LOSS OF FUNCTION VARIANTS	7	5.78e-01	-1.21e-01	8.43e-01
REACTOME VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS	42	5.78e-01	-4.96e-02	8.43e-01
REACTOME SUMOYLATION OF SUMOYLATION PROTEINS	35	5.79e-01	-5.42e-02	8.43e-01
REACTOME MISCELLANEOUS TRANSPORT AND BINDING EVENTS	24	5.79e-01	6.54e-02	8.43e-01
REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION	20	5.79e-01	7.16e-02	8.43e-01
REACTOME REGULATION OF IFNA IFNB SIGNALING	23	5.80e-01	6.67e-02	8.43e-01
REACTOME INSULIN PROCESSING	24	5.80e-01	-6.52e-02	8.43e-01
REACTOME RUNX3 REGULATES WNT SIGNALING	8	5.80e-01	1.13e-01	8.43e-01
REACTOME NUCLEAR ENVELOPE BREAKDOWN	52	5.81e-01	-4.42e-02	8.44e-01
REACTOME MEIOTIC SYNAPSIS	73	5.82e-01	-3.73e-02	8.44e-01
REACTOME LYSOSPHINGOLIPID AND LPA RECEPTORS	14	5.82e-01	-8.49e-02	8.44e-01
REACTOME BASIGIN INTERACTIONS	24	5.84e-01	6.46e-02	8.45e-01
REACTOME AMINO ACID CONJUGATION	9	5.84e-01	1.05e-01	8.45e-01
REACTOME CELLULAR RESPONSE TO HEAT STRESS	99	5.84e-01	-3.18e-02	8.45e-01
REACTOME PHOSPHORYLATION OF THE APC C	20	5.86e-01	-7.04e-02	8.46e-01
REACTOME CROSS PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS PHAGOSOMES	6	5.86e-01	1.28e-01	8.46e-01
REACTOME MTOR SIGNALLING	40	5.88e-01	4.95e-02	8.46e-01
REACTOME ROLE OF ABL IN ROBO SLIT SIGNALING	8	5.89e-01	-1.10e-01	8.46e-01
REACTOME PI5P REGULATES TP53 ACETYLATION	9	5.89e-01	1.04e-01	8.46e-01
REACTOME NOSTRIN MEDIATED ENOS TRAFFICKING	5	5.89e-01	-1.40e-01	8.46e-01
REACTOME ACTIVATION OF PPARGC1A PGC 1ALPHA BY PHOSPHORYLATION	10	5.89e-01	-9.86e-02	8.46e-01
REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	51	5.90e-01	-4.37e-02	8.46e-01
REACTOME GLUTAMATE AND GLUTAMINE METABOLISM	13	5.90e-01	-8.63e-02	8.46e-01
REACTOME APEX1 INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	7	5.92e-01	1.17e-01	8.47e-01
REACTOME COPI MEDIATED ANTEROGRADE TRANSPORT	101	5.92e-01	-3.08e-02	8.47e-01
REACTOME SPHINGOLIPID METABOLISM	84	5.93e-01	-3.38e-02	8.47e-01
REACTOME ATORVASTATIN ADME	9	5.93e-01	1.03e-01	8.47e-01
REACTOME RECYCLING OF BILE ACIDS AND SALTS	18	5.94e-01	7.27e-02	8.47e-01
REACTOME SODIUM PROTON EXCHANGERS	7	5.94e-01	1.16e-01	8.48e-01
REACTOME MELANIN BIOSYNTHESIS	5	5.95e-01	1.37e-01	8.49e-01
REACTOME COMMON PATHWAY OF FIBRIN CLOT FORMATION	21	5.97e-01	-6.67e-02	8.50e-01
REACTOME NEDDYLATION	235	5.98e-01	-2.00e-02	8.50e-01
REACTOME HDMS DEMETHYLATE HISTONES	40	5.98e-01	4.82e-02	8.50e-01
REACTOME MRNA CAPPING	28	5.98e-01	-5.76e-02	8.50e-01
REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX	85	6.04e-01	-3.26e-02	8.57e-01
REACTOME FRUCTOSE METABOLISM	7	6.07e-01	1.12e-01	8.61e-01
REACTOME REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS	7	6.11e-01	1.11e-01	8.65e-01
REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	118	6.14e-01	-2.69e-02	8.68e-01
REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	31	6.15e-01	-5.21e-02	8.68e-01
REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ	6	6.16e-01	1.18e-01	8.68e-01
REACTOME FGFRL1 MODULATION OF FGFR1 SIGNALING	13	6.16e-01	-8.04e-02	8.68e-01
REACTOME SIGNALING BY FGFR4 IN DISEASE	11	6.16e-01	8.74e-02	8.68e-01
REACTOME PEROXISOMAL LIPID METABOLISM	28	6.16e-01	-5.47e-02	8.68e-01
REACTOME RRNA PROCESSING IN THE MITOCHONDRION	9	6.19e-01	9.58e-02	8.71e-01
REACTOME IKBA VARIANT LEADS TO EDA ID	6	6.20e-01	1.17e-01	8.72e-01
REACTOME METABOLISM OF FOLATE AND PTERINES	17	6.21e-01	-6.93e-02	8.73e-01
REACTOME TRANSPORT OF NUCLEOTIDE SUGARS	8	6.21e-01	-1.01e-01	8.73e-01
REACTOME PI3K AKT ACTIVATION	9	6.22e-01	-9.49e-02	8.73e-01
REACTOME DEFECTIVE CHST14 CAUSES EDS MUSCULOCONTRACTURAL TYPE	7	6.24e-01	-1.07e-01	8.74e-01
REACTOME CRMPS IN SEMA3A SIGNALING	15	6.25e-01	7.30e-02	8.74e-01
REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	14	6.25e-01	7.55e-02	8.74e-01
REACTOME BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS	10	6.26e-01	8.91e-02	8.74e-01
REACTOME DEADENYLATION OF MRNA	25	6.26e-01	-5.64e-02	8.74e-01
REACTOME SIGNALING BY TGFB FAMILY MEMBERS	119	6.27e-01	-2.58e-02	8.74e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2	13	6.27e-01	7.78e-02	8.74e-01
REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	45	6.27e-01	4.18e-02	8.74e-01
REACTOME SIGNALING BY NTRK3 TRKC	17	6.28e-01	6.78e-02	8.75e-01
REACTOME VITAMINS	6	6.30e-01	-1.14e-01	8.76e-01
REACTOME RECEPTOR MEDIATED MITOPHAGY	10	6.31e-01	8.77e-02	8.77e-01
REACTOME ER TO GOLGI ANTEROGRADE TRANSPORT	152	6.32e-01	-2.25e-02	8.77e-01
REACTOME RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA	7	6.32e-01	-1.05e-01	8.77e-01
REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY	25	6.33e-01	5.52e-02	8.77e-01
REACTOME REGULATION OF TP53 ACTIVITY	156	6.33e-01	-2.22e-02	8.77e-01
REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION	23	6.36e-01	5.71e-02	8.80e-01
REACTOME PREDNISONE ADME	10	6.36e-01	8.64e-02	8.80e-01
REACTOME RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION	6	6.36e-01	1.11e-01	8.80e-01
REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	15	6.40e-01	-6.98e-02	8.84e-01
REACTOME ARYL HYDROCARBON RECEPTOR SIGNALLING	6	6.40e-01	1.10e-01	8.84e-01
REACTOME DEFECTIVE RIPK1 MEDIATED REGULATED NECROSIS	7	6.41e-01	1.02e-01	8.84e-01
REACTOME CYTOSOLIC TRNA AMINOACYLATION	22	6.44e-01	-5.70e-02	8.86e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE	5	6.45e-01	-1.19e-01	8.86e-01
REACTOME RAC2 GTPASE CYCLE	81	6.45e-01	-2.96e-02	8.86e-01
REACTOME KILLING MECHANISMS	11	6.45e-01	-8.02e-02	8.86e-01
REACTOME COPII MEDIATED VESICLE TRANSPORT	66	6.45e-01	-3.28e-02	8.86e-01
REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	183	6.46e-01	-1.97e-02	8.86e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH METHYLATION	19	6.47e-01	-6.07e-02	8.86e-01
REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R	52	6.47e-01	-3.67e-02	8.86e-01
REACTOME OTHER SEMAPHORIN INTERACTIONS	18	6.48e-01	-6.21e-02	8.86e-01
REACTOME COMPLEMENT CASCADE	54	6.48e-01	3.59e-02	8.86e-01
REACTOME SYNTHESIS OF KETONE BODIES	8	6.49e-01	9.28e-02	8.87e-01
REACTOME ENDOGENOUS STEROLS	26	6.50e-01	5.14e-02	8.87e-01
REACTOME POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION	27	6.51e-01	5.03e-02	8.88e-01
REACTOME PTK6 EXPRESSION	5	6.53e-01	1.16e-01	8.89e-01
REACTOME LONG TERM POTENTIATION	22	6.54e-01	-5.52e-02	8.89e-01
REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	17	6.54e-01	-6.27e-02	8.89e-01
REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	14	6.54e-01	-6.91e-02	8.89e-01
REACTOME GAP JUNCTION TRAFFICKING AND REGULATION	49	6.55e-01	-3.69e-02	8.89e-01
REACTOME EPHRIN SIGNALING	17	6.55e-01	6.26e-02	8.89e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS	12	6.57e-01	-7.41e-02	8.90e-01
REACTOME COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC	52	6.58e-01	-3.55e-02	8.90e-01
REACTOME TRNA MODIFICATION IN THE MITOCHONDRION	8	6.58e-01	-9.03e-02	8.90e-01
REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	91	6.60e-01	-2.67e-02	8.90e-01
REACTOME DISEASES OF IMMUNE SYSTEM	29	6.60e-01	-4.72e-02	8.90e-01
REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION	26	6.61e-01	-4.97e-02	8.90e-01
REACTOME NR1H2 AND NR1H3 MEDIATED SIGNALING	46	6.61e-01	3.73e-02	8.90e-01
REACTOME PREGNENOLONE BIOSYNTHESIS	12	6.61e-01	-7.31e-02	8.90e-01
REACTOME ACETYLCHOLINE REGULATES INSULIN SECRETION	10	6.62e-01	7.99e-02	8.90e-01
REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS	33	6.62e-01	-4.40e-02	8.90e-01
REACTOME NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	24	6.62e-01	5.16e-02	8.90e-01
REACTOME PROCESSING OF INTRONLESS PRE MRNAS	19	6.62e-01	-5.79e-02	8.90e-01
REACTOME UNWINDING OF DNA	12	6.63e-01	7.27e-02	8.90e-01
REACTOME SIGNALING BY LEPTIN	11	6.63e-01	-7.58e-02	8.90e-01
REACTOME FORMATION OF XYLULOSE 5 PHOSPHATE	5	6.65e-01	1.12e-01	8.91e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH PI3K	6	6.65e-01	1.02e-01	8.91e-01
REACTOME DEFECTS IN COBALAMIN B12 METABOLISM	13	6.66e-01	-6.91e-02	8.91e-01
REACTOME AQUAPORIN MEDIATED TRANSPORT	51	6.67e-01	-3.49e-02	8.92e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1	16	6.68e-01	-6.19e-02	8.92e-01
REACTOME RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION	6	6.68e-01	1.01e-01	8.92e-01
REACTOME VITAMIN B2 RIBOFLAVIN METABOLISM	7	6.69e-01	-9.33e-02	8.92e-01
REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES	29	6.72e-01	-4.55e-02	8.94e-01
REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	13	6.72e-01	-6.79e-02	8.94e-01
REACTOME ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN	13	6.72e-01	-6.78e-02	8.94e-01
REACTOME SIGNALING BY ERBB2 ECD MUTANTS	16	6.72e-01	-6.11e-02	8.94e-01
REACTOME NEF AND SIGNAL TRANSDUCTION	8	6.75e-01	-8.57e-02	8.96e-01
REACTOME ESTROGEN BIOSYNTHESIS	6	6.75e-01	-9.89e-02	8.96e-01
REACTOME SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS	16	6.77e-01	-6.02e-02	8.98e-01
REACTOME METABOLISM OF VITAMINS AND COFACTORS	185	6.77e-01	1.77e-02	8.98e-01
REACTOME LIPOPHAGY	9	6.80e-01	-7.95e-02	8.99e-01
REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES	14	6.80e-01	-6.37e-02	8.99e-01
REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	11	6.80e-01	7.19e-02	8.99e-01
REACTOME CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2	11	6.84e-01	-7.08e-02	9.04e-01
REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	57	6.87e-01	-3.09e-02	9.05e-01
REACTOME NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION	193	6.87e-01	-1.68e-02	9.05e-01
REACTOME NUCLEAR IMPORT OF REV PROTEIN	34	6.87e-01	-3.99e-02	9.05e-01
REACTOME FOXO MEDIATED TRANSCRIPTION	65	6.87e-01	-2.89e-02	9.05e-01
REACTOME SARS COV 2 MODULATES AUTOPHAGY	11	6.88e-01	6.98e-02	9.05e-01
REACTOME SUMOYLATION OF DNA REPLICATION PROTEINS	46	6.89e-01	3.41e-02	9.05e-01
REACTOME PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1	9	6.89e-01	-7.70e-02	9.05e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1	20	6.89e-01	-5.16e-02	9.05e-01
REACTOME LAGGING STRAND SYNTHESIS	19	6.92e-01	-5.26e-02	9.07e-01
REACTOME PHOSPHORYLATION OF EMI1	6	6.92e-01	-9.34e-02	9.07e-01
REACTOME GROWTH HORMONE RECEPTOR SIGNALING	24	6.92e-01	-4.66e-02	9.07e-01
REACTOME DEFECTIVE B4GALT1 CAUSES B4GALT1 CDG CDG 2D	8	6.94e-01	-8.04e-02	9.08e-01
REACTOME LDL REMODELING	6	6.95e-01	-9.25e-02	9.09e-01
REACTOME RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS	5	6.96e-01	-1.01e-01	9.09e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES	29	6.97e-01	-4.18e-02	9.09e-01
REACTOME RUNX3 REGULATES NOTCH SIGNALING	13	6.98e-01	-6.21e-02	9.09e-01
REACTOME EXTENSION OF TELOMERES	49	6.98e-01	-3.20e-02	9.09e-01
REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA	28	6.98e-01	-4.23e-02	9.09e-01
REACTOME SARS COV 1 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS	16	6.99e-01	-5.58e-02	9.09e-01
REACTOME ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT	23	6.99e-01	4.65e-02	9.09e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM	38	7.00e-01	3.61e-02	9.09e-01
REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	14	7.01e-01	-5.93e-02	9.10e-01
REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	15	7.03e-01	-5.69e-02	9.11e-01
REACTOME COENZYME A BIOSYNTHESIS	8	7.05e-01	-7.74e-02	9.13e-01
REACTOME GLUCAGON TYPE LIGAND RECEPTORS	32	7.05e-01	-3.87e-02	9.13e-01
REACTOME DEADENYLATION DEPENDENT MRNA DECAY	56	7.07e-01	-2.90e-02	9.14e-01
REACTOME LATE SARS COV 2 INFECTION EVENTS	67	7.07e-01	2.66e-02	9.14e-01
REACTOME CYP2E1 REACTIONS	10	7.09e-01	-6.81e-02	9.14e-01
REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	8	7.10e-01	-7.60e-02	9.14e-01
REACTOME ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS	5	7.10e-01	9.61e-02	9.14e-01
REACTOME INSULIN RECEPTOR RECYCLING	29	7.10e-01	3.99e-02	9.14e-01
REACTOME MIRO GTPASE CYCLE	8	7.10e-01	7.59e-02	9.14e-01
REACTOME NUCLEAR PORE COMPLEX NPC DISASSEMBLY	36	7.11e-01	-3.57e-02	9.14e-01
REACTOME SARS COV 2 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS	12	7.12e-01	6.16e-02	9.14e-01
REACTOME SYNTHESIS OF PE	13	7.13e-01	-5.89e-02	9.14e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX	19	7.13e-01	-4.87e-02	9.14e-01
REACTOME NADE MODULATES DEATH SIGNALLING	5	7.14e-01	-9.46e-02	9.14e-01
REACTOME FRS MEDIATED FGFR4 SIGNALING	21	7.14e-01	-4.62e-02	9.14e-01
REACTOME CALCINEURIN ACTIVATES NFAT	9	7.15e-01	-7.03e-02	9.14e-01
REACTOME INITIATION OF NUCLEAR ENVELOPE NE REFORMATION	18	7.15e-01	-4.97e-02	9.14e-01
REACTOME KINESINS	59	7.15e-01	2.75e-02	9.14e-01
REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	13	7.15e-01	5.84e-02	9.14e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS	15	7.17e-01	-5.40e-02	9.16e-01
REACTOME GLUCONEOGENESIS	33	7.18e-01	-3.63e-02	9.16e-01
REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	21	7.19e-01	4.54e-02	9.16e-01
REACTOME ACTIVATION OF RAS IN B CELLS	5	7.19e-01	-9.29e-02	9.16e-01
REACTOME REGULATION OF TP53 EXPRESSION AND DEGRADATION	37	7.20e-01	3.41e-02	9.16e-01
REACTOME GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION	30	7.20e-01	3.78e-02	9.16e-01
REACTOME COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC	98	7.23e-01	-2.07e-02	9.19e-01
REACTOME SIGNAL TRANSDUCTION BY L1	20	7.24e-01	4.56e-02	9.19e-01
REACTOME STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES	16	7.24e-01	-5.10e-02	9.19e-01
REACTOME DISINHIBITION OF SNARE FORMATION	5	7.24e-01	-9.10e-02	9.19e-01
REACTOME PENTOSE PHOSPHATE PATHWAY	12	7.25e-01	5.86e-02	9.19e-01
REACTOME SYNTHESIS OF PC	27	7.26e-01	3.89e-02	9.19e-01
REACTOME RSK ACTIVATION	5	7.28e-01	9.00e-02	9.20e-01
REACTOME INOSITOL PHOSPHATE METABOLISM	45	7.28e-01	3.00e-02	9.20e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX IN CANCER	8	7.29e-01	-7.07e-02	9.20e-01
REACTOME SIGNAL ATTENUATION	10	7.31e-01	6.29e-02	9.20e-01
REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY	5	7.31e-01	8.88e-02	9.20e-01
REACTOME TIGHT JUNCTION INTERACTIONS	29	7.31e-01	-3.69e-02	9.20e-01
REACTOME ACTIVATION OF CASPASES THROUGH APOPTOSOME MEDIATED CLEAVAGE	5	7.32e-01	-8.85e-02	9.20e-01
REACTOME ASPARAGINE N LINKED GLYCOSYLATION	299	7.32e-01	-1.15e-02	9.20e-01
REACTOME ENOS ACTIVATION	11	7.33e-01	5.94e-02	9.20e-01
REACTOME SIGNALING BY FGFR2 IIIA TM	19	7.33e-01	-4.51e-02	9.20e-01
REACTOME ROBO RECEPTORS BIND AKAP5	9	7.34e-01	-6.55e-02	9.20e-01
REACTOME TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS	43	7.34e-01	-2.99e-02	9.20e-01
REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	29	7.35e-01	3.64e-02	9.20e-01
REACTOME TELOMERE EXTENSION BY TELOMERASE	22	7.35e-01	-4.17e-02	9.20e-01
REACTOME CREATINE METABOLISM	9	7.36e-01	-6.50e-02	9.20e-01
REACTOME POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE	25	7.37e-01	3.89e-02	9.20e-01
REACTOME MULTIFUNCTIONAL ANION EXCHANGERS	9	7.38e-01	-6.44e-02	9.20e-01
REACTOME RAC3 GTPASE CYCLE	85	7.38e-01	-2.10e-02	9.20e-01
REACTOME LINOLEIC ACID LA METABOLISM	7	7.39e-01	7.29e-02	9.20e-01
REACTOME SUMOYLATION	179	7.39e-01	-1.44e-02	9.20e-01
REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	63	7.40e-01	2.42e-02	9.20e-01
REACTOME ACTIVATION OF NIMA KINASES NEK9 NEK6 NEK7	7	7.40e-01	-7.23e-02	9.20e-01
REACTOME GAP JUNCTION ASSEMBLY	36	7.41e-01	-3.19e-02	9.20e-01
REACTOME BH3 ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI APOPTOTIC BCL 2 MEMBERS	9	7.42e-01	-6.35e-02	9.20e-01
REACTOME FRUCTOSE CATABOLISM	5	7.42e-01	8.51e-02	9.20e-01
REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS	15	7.42e-01	4.91e-02	9.20e-01
REACTOME CA2 ACTIVATED K CHANNELS	9	7.42e-01	6.33e-02	9.20e-01
REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	23	7.43e-01	-3.95e-02	9.20e-01
REACTOME METABOLISM OF AMINE DERIVED HORMONES	17	7.44e-01	4.58e-02	9.20e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH RAS	8	7.44e-01	-6.67e-02	9.20e-01
REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF	17	7.45e-01	-4.56e-02	9.21e-01
REACTOME ACYL CHAIN REMODELING OF CL	5	7.46e-01	-8.38e-02	9.21e-01
REACTOME RETINOID CYCLE DISEASE EVENTS	11	7.47e-01	5.62e-02	9.21e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST	18	7.47e-01	-4.39e-02	9.21e-01
REACTOME HS GAG BIOSYNTHESIS	28	7.50e-01	-3.47e-02	9.21e-01
REACTOMEMATURATION OF SARS COV 1 NUCLEOPROTEIN	11	7.52e-01	5.50e-02	9.21e-01
REACTOME RESPONSE OF MTB TO PHAGOCYTOSIS	22	7.52e-01	-3.89e-02	9.21e-01
REACTOME ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS	20	7.52e-01	-4.08e-02	9.21e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES	12	7.53e-01	-5.25e-02	9.21e-01
REACTOME RUNX3 REGULATES BCL2L11 BIM TRANSCRIPTION	5	7.53e-01	-8.12e-02	9.21e-01
REACTOME LOSS OF FUNCTION OF SMAD2 3 IN CANCER	7	7.54e-01	-6.85e-02	9.21e-01
REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS	63	7.54e-01	2.28e-02	9.21e-01
REACTOME ATTACHMENT OF GPI ANCHOR TO UPAR	7	7.55e-01	-6.82e-02	9.21e-01
REACTOME DEFECTIVE CHST6 CAUSES MCDC1	8	7.55e-01	6.37e-02	9.21e-01
REACTOME METABOLISM OF INGESTED SEMET SEC MESEC INTO H2SE	7	7.55e-01	6.80e-02	9.21e-01
REACTOME PTEN REGULATION	135	7.55e-01	1.55e-02	9.21e-01
REACTOME FATTY ACYL COA BIOSYNTHESIS	36	7.55e-01	-3.00e-02	9.21e-01
REACTOME AURKA ACTIVATION BY TPX2	69	7.55e-01	-2.17e-02	9.21e-01
REACTOME PURINE SALVAGE	12	7.56e-01	-5.19e-02	9.21e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD4	15	7.56e-01	-4.64e-02	9.21e-01
REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	32	7.56e-01	-3.17e-02	9.21e-01
REACTOME REGULATION OF NF KAPPA B SIGNALING	17	7.57e-01	-4.33e-02	9.22e-01
REACTOME SIGNALING BY NODAL	20	7.58e-01	-3.99e-02	9.22e-01
REACTOME NETRIN MEDIATED REPULSION SIGNALS	8	7.58e-01	-6.28e-02	9.22e-01
REACTOME SIGNALING BY WNT IN CANCER	32	7.59e-01	-3.14e-02	9.22e-01
REACTOME REGULATION OF SIGNALING BY NODAL	9	7.59e-01	5.90e-02	9.22e-01
REACTOME SIGNALING BY MET	78	7.60e-01	2.00e-02	9.22e-01
REACTOME ERKS ARE INACTIVATED	13	7.61e-01	-4.86e-02	9.22e-01
REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS	43	7.62e-01	-2.67e-02	9.22e-01
REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	11	7.63e-01	-5.25e-02	9.23e-01
REACTOME METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS	122	7.63e-01	-1.58e-02	9.23e-01
REACTOME SMAC XIAP REGULATED APOPTOTIC RESPONSE	7	7.64e-01	-6.56e-02	9.23e-01
REACTOME MATURATION OF SARS COV 2 NUCLEOPROTEIN	15	7.65e-01	-4.46e-02	9.23e-01
REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	16	7.66e-01	4.30e-02	9.23e-01
REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA	11	7.66e-01	-5.19e-02	9.23e-01
REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	11	7.67e-01	-5.16e-02	9.24e-01
REACTOME NEUROTOXICITY OF CLOSTRIDIUM TOXINS	10	7.69e-01	-5.37e-02	9.25e-01
REACTOME MITOCHONDRIAL CALCIUM ION TRANSPORT	23	7.70e-01	3.53e-02	9.25e-01
REACTOME ALPHA OXIDATION OF PHYTANATE	6	7.70e-01	-6.90e-02	9.25e-01
REACTOME CD28 CO STIMULATION	32	7.71e-01	2.98e-02	9.25e-01
REACTOME HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS	7	7.71e-01	6.35e-02	9.25e-01
REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	18	7.74e-01	-3.91e-02	9.29e-01
REACTOME WNT MEDIATED ACTIVATION OF DVL	8	7.76e-01	-5.82e-02	9.29e-01
REACTOME HEME BIOSYNTHESIS	13	7.76e-01	-4.56e-02	9.29e-01
REACTOME INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	28	7.76e-01	-3.11e-02	9.29e-01
REACTOME PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR	21	7.78e-01	-3.56e-02	9.30e-01
REACTOME TBC RABGAPS	40	7.81e-01	2.54e-02	9.33e-01
REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN	37	7.81e-01	2.64e-02	9.33e-01
REACTOME TYROSINE CATABOLISM	5	7.83e-01	-7.10e-02	9.35e-01
REACTOME TRANSPORT AND SYNTHESIS OF PAPS	6	7.84e-01	6.46e-02	9.35e-01
REACTOME HORMONE LIGAND BINDING RECEPTORS	12	7.85e-01	4.55e-02	9.35e-01
REACTOME CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE	49	7.87e-01	-2.23e-02	9.37e-01
REACTOME TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS	29	7.87e-01	2.89e-02	9.37e-01
REACTOME PHASE 0 RAPID DEPOLARISATION	31	7.90e-01	-2.76e-02	9.39e-01
REACTOME RHO GTPASES ACTIVATE FORMINS	136	7.90e-01	-1.32e-02	9.39e-01
REACTOME INTERLEUKIN 23 SIGNALING	9	7.91e-01	5.10e-02	9.39e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES	61	7.93e-01	-1.95e-02	9.40e-01
REACTOME ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS	27	7.93e-01	-2.92e-02	9.40e-01
REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS	14	7.95e-01	4.02e-02	9.41e-01
REACTOME DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS	19	7.96e-01	3.42e-02	9.42e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE	11	7.97e-01	4.48e-02	9.42e-01
REACTOME KERATAN SULFATE DEGRADATION	13	7.97e-01	4.12e-02	9.42e-01
REACTOME SOS MEDIATED SIGNALLING	7	7.98e-01	5.59e-02	9.42e-01
REACTOME MET INTERACTS WITH TNS PROTEINS	5	7.98e-01	-6.60e-02	9.42e-01
REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	160	7.99e-01	-1.17e-02	9.42e-01
REACTOME MYOGENESIS	29	7.99e-01	-2.73e-02	9.42e-01
REACTOME RESPONSE TO METAL IONS	14	8.01e-01	-3.90e-02	9.42e-01
REACTOME WAX AND PLASMALOGEN BIOSYNTHESIS	5	8.01e-01	-6.50e-02	9.42e-01
REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS	68	8.02e-01	1.76e-02	9.42e-01
REACTOME SCAVENGING BY CLASS A RECEPTORS	19	8.02e-01	3.33e-02	9.42e-01
REACTOME DISEASES OF MISMATCH REPAIR MMR	5	8.02e-01	-6.47e-02	9.42e-01
REACTOME GRB7 EVENTS IN ERBB2 SIGNALING	5	8.05e-01	6.37e-02	9.44e-01
REACTOME HIV ELONGATION ARREST AND RECOVERY	33	8.05e-01	-2.48e-02	9.44e-01
REACTOME RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION	8	8.06e-01	5.01e-02	9.44e-01
REACTOME CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT	19	8.06e-01	-3.25e-02	9.44e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K	12	8.07e-01	-4.08e-02	9.44e-01
REACTOME BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA	5	8.08e-01	-6.28e-02	9.45e-01
REACTOME LDL CLEARANCE	19	8.09e-01	3.20e-02	9.45e-01
REACTOME MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS	17	8.10e-01	-3.38e-02	9.45e-01
REACTOME MAP2K AND MAPK ACTIVATION	38	8.10e-01	-2.25e-02	9.45e-01
REACTOME SLC TRANSPORTER DISORDERS	94	8.11e-01	1.43e-02	9.45e-01
REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	52	8.13e-01	-1.90e-02	9.47e-01
REACTOME KERATAN SULFATE BIOSYNTHESIS	28	8.13e-01	-2.58e-02	9.47e-01
REACTOME TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER	76	8.14e-01	-1.56e-02	9.47e-01
REACTOME ACTIVATION OF RAC1	12	8.15e-01	-3.90e-02	9.47e-01
REACTOME REACTIONS SPECIFIC TO THE COMPLEX N GLYCAN SYNTHESIS PATHWAY	10	8.16e-01	4.25e-02	9.47e-01
REACTOME ONCOGENIC MAPK SIGNALING	79	8.18e-01	-1.50e-02	9.47e-01
REACTOME METHIONINE SALVAGE PATHWAY	6	8.18e-01	-5.43e-02	9.47e-01
REACTOME DSCAM INTERACTIONS	11	8.18e-01	-4.01e-02	9.47e-01
REACTOME SODIUM CALCIUM EXCHANGERS	11	8.19e-01	3.99e-02	9.47e-01
REACTOME RET SIGNALING	40	8.19e-01	2.09e-02	9.47e-01
REACTOME ABACAVIR ADME	9	8.19e-01	-4.41e-02	9.47e-01
REACTOME NGF INDEPENDANT TRKA ACTIVATION	5	8.19e-01	-5.90e-02	9.47e-01
REACTOME DISEASES OF CARBOHYDRATE METABOLISM	31	8.20e-01	2.36e-02	9.47e-01
REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	20	8.20e-01	-2.93e-02	9.47e-01
REACTOME BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA	17	8.26e-01	3.08e-02	9.53e-01
REACTOME P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1	6	8.27e-01	5.17e-02	9.53e-01
REACTOME SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS	74	8.28e-01	1.46e-02	9.53e-01
REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS	299	8.28e-01	-7.29e-03	9.53e-01
REACTOME DUAL INCISION IN TC NER	63	8.28e-01	-1.58e-02	9.53e-01
REACTOME SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS	14	8.32e-01	-3.27e-02	9.55e-01
REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	9	8.33e-01	4.07e-02	9.55e-01
REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES	34	8.33e-01	2.09e-02	9.55e-01
REACTOME SERINE BIOSYNTHESIS	9	8.34e-01	-4.03e-02	9.55e-01
REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	17	8.34e-01	2.93e-02	9.55e-01
REACTOME METALLOTHIONEINS BIND METALS	11	8.37e-01	-3.59e-02	9.55e-01
REACTOME UPTAKE AND ACTIONS OF BACTERIAL TOXINS	28	8.37e-01	-2.25e-02	9.55e-01
REACTOME INTERFERON GAMMA SIGNALING	88	8.37e-01	-1.27e-02	9.55e-01
REACTOME CONDENSATION OF PROMETAPHASE CHROMOSOMES	11	8.37e-01	-3.58e-02	9.55e-01
REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES	7	8.37e-01	-4.48e-02	9.55e-01
REACTOME DEX H BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION	7	8.37e-01	-4.48e-02	9.55e-01
REACTOME PROLACTIN RECEPTOR SIGNALING	15	8.38e-01	-3.05e-02	9.55e-01
REACTOME TRANSPORT OF ORGANIC ANIONS	10	8.38e-01	-3.73e-02	9.55e-01
REACTOME SUMOYLATION OF INTRACELLULAR RECEPTORS	29	8.38e-01	2.19e-02	9.55e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING	25	8.39e-01	2.34e-02	9.55e-01
REACTOME RAB REGULATION OF TRAFFICKING	110	8.40e-01	-1.12e-02	9.55e-01
REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	122	8.40e-01	1.06e-02	9.55e-01
REACTOME BETA CATENIN PHOSPHORYLATION CASCADE	16	8.41e-01	-2.89e-02	9.56e-01
REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION	42	8.42e-01	-1.78e-02	9.56e-01
REACTOME PHASE 4 RESTING MEMBRANE POTENTIAL	19	8.44e-01	-2.61e-02	9.57e-01
REACTOME MRNA EDITING	10	8.44e-01	3.59e-02	9.57e-01
REACTOME NEUROFASCIN INTERACTIONS	6	8.47e-01	4.56e-02	9.60e-01
REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	14	8.47e-01	-2.97e-02	9.60e-01
REACTOME INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION	21	8.48e-01	-2.41e-02	9.60e-01
REACTOME BETA OXIDATION OF PRISTANOYL COA	9	8.50e-01	-3.64e-02	9.60e-01
REACTOME MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS	7	8.51e-01	-4.10e-02	9.60e-01
REACTOME EICOSANOIDS	12	8.51e-01	3.13e-02	9.60e-01
REACTOME SYNAPTIC ADHESION LIKE MOLECULES	19	8.52e-01	2.47e-02	9.60e-01
REACTOME CELL JUNCTION ORGANIZATION	89	8.52e-01	1.14e-02	9.60e-01
REACTOME MITOCHONDRIAL UNCOUPLING	5	8.53e-01	-4.80e-02	9.60e-01
REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND	21	8.53e-01	-2.34e-02	9.60e-01
REACTOME FORMATION OF TC NER PRE INCISION COMPLEX	51	8.53e-01	-1.50e-02	9.60e-01
REACTOME RIBAVIRIN ADME	11	8.55e-01	-3.19e-02	9.60e-01
REACTOME CD209 DC SIGN SIGNALING	20	8.55e-01	2.36e-02	9.60e-01
REACTOME BILE ACID AND BILE SALT METABOLISM	45	8.55e-01	1.57e-02	9.60e-01
REACTOME FORMATION OF PARAXIAL MESODERM	22	8.56e-01	-2.23e-02	9.60e-01
REACTOME PLASMA LIPOPROTEIN CLEARANCE	37	8.59e-01	-1.69e-02	9.60e-01
REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	9	8.60e-01	3.40e-02	9.60e-01
REACTOME THE ACTIVATION OF ARYLSULFATASES	8	8.60e-01	-3.60e-02	9.60e-01
REACTOME REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO	10	8.60e-01	-3.22e-02	9.60e-01
REACTOME TRIGLYCERIDE CATABOLISM	23	8.61e-01	-2.12e-02	9.60e-01
REACTOME DISEASES OF BASE EXCISION REPAIR	5	8.61e-01	-4.54e-02	9.60e-01
REACTOME SYNTHESIS OF DOLICHYL PHOSPHATE	6	8.62e-01	4.11e-02	9.60e-01
REACTOME UREA CYCLE	9	8.62e-01	3.35e-02	9.60e-01
REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING	25	8.62e-01	2.01e-02	9.60e-01
REACTOME SIGNALING BY RNF43 MUTANTS	8	8.62e-01	-3.55e-02	9.60e-01
REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	30	8.63e-01	1.83e-02	9.60e-01
REACTOME SEMAPHORIN INTERACTIONS	61	8.63e-01	1.28e-02	9.60e-01
REACTOME MINERALOCORTICOID BIOSYNTHESIS	6	8.63e-01	4.07e-02	9.60e-01
REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	16	8.67e-01	-2.42e-02	9.64e-01
REACTOME SUMOYLATION OF UBIQUITINYLATION PROTEINS	39	8.67e-01	-1.54e-02	9.64e-01
REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX	21	8.69e-01	2.08e-02	9.64e-01
REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	30	8.69e-01	1.74e-02	9.64e-01
REACTOME DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15	8	8.70e-01	3.34e-02	9.64e-01
REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE	93	8.71e-01	9.78e-03	9.64e-01
REACTOME CHOLINE CATABOLISM	6	8.71e-01	3.82e-02	9.64e-01
REACTOME SIGNALING BY MRAS COMPLEX MUTANTS	7	8.71e-01	3.53e-02	9.64e-01
REACTOME PASSIVE TRANSPORT BY AQUAPORINS	13	8.71e-01	2.59e-02	9.64e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING	5	8.73e-01	-4.14e-02	9.64e-01
REACTOME O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS	38	8.73e-01	1.50e-02	9.64e-01
REACTOME GLUCURONIDATION	23	8.76e-01	1.89e-02	9.65e-01
REACTOME SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER	15	8.76e-01	-2.32e-02	9.65e-01
REACTOME KERATAN SULFATE KERATIN METABOLISM	34	8.78e-01	-1.53e-02	9.65e-01
REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	17	8.78e-01	-2.15e-02	9.65e-01
REACTOME FCGR3A MEDIATED IL10 SYNTHESIS	36	8.79e-01	1.47e-02	9.65e-01
REACTOME DEATH RECEPTOR SIGNALING	143	8.79e-01	7.39e-03	9.65e-01
REACTOME SCAVENGING BY CLASS B RECEPTORS	6	8.79e-01	3.58e-02	9.65e-01
REACTOME ANDROGEN BIOSYNTHESIS	11	8.79e-01	-2.64e-02	9.65e-01
REACTOME ARACHIDONIC ACID METABOLISM	57	8.79e-01	-1.16e-02	9.65e-01
REACTOME CTLA4 INHIBITORY SIGNALING	21	8.81e-01	-1.89e-02	9.65e-01
REACTOME VLDL ASSEMBLY	5	8.81e-01	-3.87e-02	9.65e-01
REACTOME G1 S SPECIFIC TRANSCRIPTION	28	8.82e-01	-1.63e-02	9.65e-01
REACTOME CHROMATIN MODIFYING ENZYMES	252	8.82e-01	5.41e-03	9.65e-01
REACTOME TRANSCRIPTIONAL REGULATION BY VENTX	41	8.83e-01	1.33e-02	9.65e-01
REACTOME SUPPRESSION OF APOPTOSIS	7	8.83e-01	-3.20e-02	9.65e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	36	8.83e-01	1.41e-02	9.65e-01
REACTOME RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR	19	8.84e-01	1.94e-02	9.65e-01
REACTOME MITOTIC TELOPHASE CYTOKINESIS	11	8.85e-01	-2.51e-02	9.65e-01
REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	26	8.86e-01	1.63e-02	9.65e-01
REACTOME DEGRADATION OF CYSTEINE AND HOMOCYSTEINE	15	8.87e-01	-2.12e-02	9.65e-01
REACTOME OAS ANTIVIRAL RESPONSE	8	8.87e-01	2.89e-02	9.65e-01
REACTOME TOXICITY OF BOTULINUM TOXIN TYPE D BOTD	5	8.88e-01	3.64e-02	9.65e-01
REACTOME SYNTHESIS OF DIPHTHAMIDE EEF2	8	8.88e-01	-2.88e-02	9.65e-01
REACTOME ACYL CHAIN REMODELLING OF PE	29	8.88e-01	1.51e-02	9.65e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	24	8.89e-01	1.64e-02	9.65e-01
REACTOME LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME	11	8.90e-01	2.41e-02	9.65e-01
REACTOME VOLTAGE GATED POTASSIUM CHANNELS	42	8.90e-01	1.23e-02	9.65e-01
REACTOME PROCESSING OF SMDT1	16	8.90e-01	-1.99e-02	9.65e-01
REACTOME SARS COV 2 TARGETS PDZ PROTEINS IN CELL CELL JUNCTION	5	8.93e-01	3.48e-02	9.67e-01
REACTOME TRANSPORT OF RCBL WITHIN THE BODY	8	8.94e-01	2.73e-02	9.67e-01
REACTOME SUMOYLATION OF DNA METHYLATION PROTEINS	16	8.94e-01	1.92e-02	9.67e-01
REACTOME HSF1 DEPENDENT TRANSACTIVATION	37	8.96e-01	-1.24e-02	9.68e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	34	8.97e-01	-1.29e-02	9.68e-01
REACTOME RHOF GTPASE CYCLE	40	8.97e-01	-1.18e-02	9.68e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN	13	8.98e-01	2.05e-02	9.68e-01
REACTOME FIBRONECTIN MATRIX FORMATION	6	8.99e-01	3.00e-02	9.68e-01
REACTOME CA2 PATHWAY	62	8.99e-01	9.34e-03	9.68e-01
REACTOME GLUTATHIONE CONJUGATION	33	8.99e-01	-1.28e-02	9.68e-01
REACTOME SYNTHESIS OF GDP MANNOSE	5	8.99e-01	-3.26e-02	9.68e-01
REACTOME MITOTIC SPINDLE CHECKPOINT	109	9.01e-01	-6.86e-03	9.69e-01
REACTOME LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX	5	9.02e-01	-3.19e-02	9.69e-01
REACTOME CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND	9	9.02e-01	2.36e-02	9.69e-01
REACTOME N GLYCAN TRIMMING AND ELONGATION IN THE CIS GOLGI	5	9.03e-01	3.13e-02	9.70e-01
REACTOME EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION	27	9.05e-01	-1.32e-02	9.70e-01
REACTOME PROPIONYL COA CATABOLISM	5	9.06e-01	3.06e-02	9.70e-01
REACTOME SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION	8	9.06e-01	2.42e-02	9.70e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN	21	9.06e-01	-1.49e-02	9.70e-01
REACTOME REGULATION OF RUNX1 EXPRESSION AND ACTIVITY	17	9.09e-01	-1.60e-02	9.72e-01
REACTOME CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN	45	9.09e-01	-9.86e-03	9.72e-01
REACTOME ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS	20	9.10e-01	1.46e-02	9.72e-01
REACTOME VITAMIN D CALCIFEROL METABOLISM	12	9.10e-01	1.88e-02	9.72e-01
REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	26	9.11e-01	-1.26e-02	9.72e-01
REACTOME RAP1 SIGNALLING	16	9.13e-01	1.58e-02	9.73e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG	7	9.13e-01	2.38e-02	9.73e-01
REACTOME FERTILIZATION	26	9.14e-01	-1.22e-02	9.74e-01
REACTOME ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA	15	9.19e-01	1.52e-02	9.77e-01
REACTOME INACTIVATION OF CDC42 AND RAC1	8	9.19e-01	-2.08e-02	9.77e-01
REACTOME DOPAMINE RECEPTORS	5	9.20e-01	-2.59e-02	9.78e-01
REACTOME MTORC1 MEDIATED SIGNALLING	23	9.22e-01	-1.19e-02	9.78e-01
REACTOME INTRAFLAGELLAR TRANSPORT	50	9.22e-01	-8.04e-03	9.78e-01
REACTOME KSRP KHSRP BINDS AND DESTABILIZES MRNA	17	9.22e-01	1.37e-02	9.78e-01
REACTOME REGULATION OF LIPID METABOLISM BY PPARALPHA	115	9.23e-01	-5.20e-03	9.78e-01
REACTOME RUNX3 REGULATES YAP1 MEDIATED TRANSCRIPTION	8	9.24e-01	-1.96e-02	9.78e-01
REACTOME INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS	37	9.24e-01	-9.02e-03	9.78e-01
REACTOME NEPHRIN FAMILY INTERACTIONS	22	9.25e-01	1.17e-02	9.78e-01
REACTOME RHOT1 GTPASE CYCLE	5	9.25e-01	-2.43e-02	9.78e-01
REACTOME HUR ELAVL1 BINDS AND STABILIZES MRNA	8	9.26e-01	1.91e-02	9.78e-01
REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	23	9.26e-01	-1.11e-02	9.78e-01
REACTOME INTERLEUKIN 18 SIGNALING	8	9.27e-01	-1.87e-02	9.78e-01
REACTOME MOLYBDENUM COFACTOR BIOSYNTHESIS	6	9.27e-01	-2.15e-02	9.78e-01
REACTOME REGULATION OF INSULIN SECRETION	77	9.28e-01	-5.97e-03	9.78e-01
REACTOME RUNX3 REGULATES CDKN1A TRANSCRIPTION	7	9.28e-01	1.96e-02	9.78e-01
REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	32	9.31e-01	-8.84e-03	9.80e-01
REACTOME FANCONI ANEMIA PATHWAY	35	9.31e-01	8.42e-03	9.80e-01
REACTOME CILIUM ASSEMBLY	190	9.33e-01	3.56e-03	9.80e-01
REACTOME CARDIAC CONDUCTION	125	9.33e-01	4.35e-03	9.80e-01
REACTOME CELL CELL COMMUNICATION	126	9.34e-01	-4.26e-03	9.81e-01
REACTOME RUNX3 REGULATES P14 ARF	10	9.35e-01	1.50e-02	9.81e-01
REACTOME SUMOYLATION OF TRANSCRIPTION FACTORS	20	9.36e-01	-1.05e-02	9.81e-01
REACTOME IRS MEDIATED SIGNALLING	47	9.37e-01	-6.71e-03	9.81e-01
REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	10	9.37e-01	-1.43e-02	9.82e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS	9	9.39e-01	1.47e-02	9.83e-01
REACTOME TELOMERE C STRAND SYNTHESIS INITIATION	12	9.40e-01	-1.25e-02	9.83e-01
REACTOME PP2A MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS	6	9.41e-01	1.75e-02	9.83e-01
REACTOME RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY	14	9.41e-01	-1.14e-02	9.83e-01
REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	9	9.43e-01	1.38e-02	9.84e-01
REACTOME DEFECTS IN VITAMIN AND COFACTOR METABOLISM	21	9.44e-01	8.90e-03	9.84e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES	15	9.45e-01	1.04e-02	9.84e-01
REACTOME GLYCOSPHINGOLIPID METABOLISM	39	9.45e-01	-6.40e-03	9.84e-01
REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	17	9.45e-01	9.62e-03	9.84e-01
REACTOME LIPID PARTICLE ORGANIZATION	6	9.49e-01	-1.52e-02	9.84e-01
REACTOME TRNA AMINOACYLATION	40	9.49e-01	5.87e-03	9.84e-01
REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	46	9.49e-01	5.44e-03	9.84e-01
REACTOME DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE	30	9.50e-01	-6.64e-03	9.84e-01
REACTOME TERMINAL PATHWAY OF COMPLEMENT	8	9.50e-01	-1.28e-02	9.84e-01
REACTOME INSULIN RECEPTOR SIGNALLING CASCADE	53	9.51e-01	-4.87e-03	9.84e-01
REACTOME ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS	10	9.52e-01	1.11e-02	9.84e-01
REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	10	9.52e-01	1.10e-02	9.84e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR4	14	9.52e-01	9.31e-03	9.84e-01
REACTOME ZINC TRANSPORTERS	15	9.52e-01	-9.00e-03	9.84e-01
REACTOME PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING	11	9.52e-01	-1.04e-02	9.84e-01
REACTOME RIP MEDIATED NFKB ACTIVATION VIA ZBP1	16	9.53e-01	8.58e-03	9.84e-01
REACTOME POTENTIAL THERAPEUTICS FOR SARS	92	9.55e-01	-3.44e-03	9.86e-01
REACTOME METABOLISM OF POLYAMINES	56	9.56e-01	-4.24e-03	9.87e-01
REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX	32	9.58e-01	5.44e-03	9.87e-01
REACTOME MISMATCH REPAIR	15	9.58e-01	7.88e-03	9.87e-01
REACTOME PHYSIOLOGICAL FACTORS	14	9.60e-01	7.79e-03	9.89e-01
REACTOME G PROTEIN BETA GAMMA SIGNALLING	30	9.63e-01	4.92e-03	9.90e-01
REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	14	9.63e-01	7.16e-03	9.90e-01
REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	49	9.64e-01	-3.76e-03	9.90e-01
REACTOME DEFECTIVE CHSY1 CAUSES TPBS	7	9.64e-01	9.94e-03	9.90e-01
REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS	81	9.64e-01	-2.91e-03	9.90e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS	7	9.65e-01	9.58e-03	9.90e-01
REACTOME RHO GTPASE CYCLE	423	9.67e-01	-1.19e-03	9.90e-01
REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX	39	9.68e-01	-3.75e-03	9.90e-01
REACTOME RHOD GTPASE CYCLE	49	9.68e-01	3.33e-03	9.90e-01
REACTOME DNA STRAND ELONGATION	31	9.69e-01	-4.09e-03	9.90e-01
REACTOME ASPARTATE AND ASPARAGINE METABOLISM	11	9.69e-01	6.78e-03	9.90e-01
REACTOME METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION	15	9.69e-01	-5.80e-03	9.90e-01
REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES	78	9.69e-01	-2.54e-03	9.90e-01
REACTOME FGFR1B LIGAND BINDING AND ACTIVATION	6	9.70e-01	-8.80e-03	9.91e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	25	9.71e-01	-4.24e-03	9.91e-01
REACTOME SULFUR AMINO ACID METABOLISM	27	9.73e-01	3.71e-03	9.93e-01
REACTOME CIPROFLOXACIN ADME	5	9.75e-01	-8.14e-03	9.93e-01
REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION	74	9.75e-01	2.11e-03	9.93e-01
REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE	19	9.76e-01	4.00e-03	9.93e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION	45	9.77e-01	2.45e-03	9.93e-01
REACTOME NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	19	9.78e-01	-3.69e-03	9.93e-01
REACTOME GLYCOGEN METABOLISM	22	9.78e-01	3.41e-03	9.93e-01
REACTOME AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY	8	9.79e-01	5.35e-03	9.93e-01
REACTOME DEPOLYMERISATION OF THE NUCLEAR LAMINA	14	9.79e-01	4.02e-03	9.93e-01
REACTOME RHOBTB3 ATPASE CYCLE	8	9.80e-01	-5.09e-03	9.93e-01
REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS	5	9.80e-01	6.38e-03	9.93e-01
REACTOME SYNTHESIS OF UDP N ACETYL GLUCOSAMINE	7	9.80e-01	-5.35e-03	9.93e-01
REACTOME ATTACHMENT AND ENTRY	16	9.81e-01	3.37e-03	9.93e-01
REACTOME COHESIN LOADING ONTO CHROMATIN	8	9.83e-01	-4.43e-03	9.93e-01
REACTOME GPER1 SIGNALING	45	9.83e-01	1.82e-03	9.93e-01
REACTOME RND3 GTPASE CYCLE	41	9.83e-01	-1.87e-03	9.93e-01
REACTOME TELOMERE C STRAND LAGGING STRAND SYNTHESIS	33	9.83e-01	-2.08e-03	9.93e-01
REACTOME G2 M DNA REPLICATION CHECKPOINT	5	9.86e-01	-4.69e-03	9.95e-01
REACTOME RHOJ GTPASE CYCLE	51	9.88e-01	1.19e-03	9.95e-01
REACTOME RND1 GTPASE CYCLE	41	9.89e-01	-1.25e-03	9.95e-01
REACTOME RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES	16	9.89e-01	1.98e-03	9.95e-01
REACTOME SIGNALING BY INSULIN RECEPTOR	80	9.89e-01	-8.77e-04	9.95e-01
REACTOME SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS	43	9.90e-01	1.14e-03	9.95e-01
REACTOME ORGANIC CATION TRANSPORT	10	9.90e-01	2.24e-03	9.95e-01
REACTOME GENE SILENCING BY RNA	133	9.90e-01	6.10e-04	9.95e-01
REACTOME UNFOLDED PROTEIN RESPONSE UPR	88	9.94e-01	-4.81e-04	9.98e-01
REACTOME FATTY ACID METABOLISM	170	9.94e-01	-3.32e-04	9.98e-01
REACTOME GOLGI TO ER RETROGRADE TRANSPORT	132	9.96e-01	2.31e-04	9.99e-01
REACTOME TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA	17	9.99e-01	1.18e-04	1.00e+00
REACTOME RESOLUTION OF ABASIC SITES AP SITES	38	9.99e-01	6.23e-05	1.00e+00
REACTOME CELLULAR HEXOSE TRANSPORT	21	1.00e+00	-6.06e-05	1.00e+00
REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	30	1.00e+00	3.94e-05	1.00e+00
REACTOME TRANSCRIPTIONAL REGULATION BY MECP2	60	1.00e+00	-1.67e-05	1.00e+00

---

Detailed Gene set reports

REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE

REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE

	271
set	REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE
setSize	105
pANOVA	7.36e-08
s.dist	-0.304
p.adjustANOVA	4.37e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL29	-10734.0
RPS12	-10480.0
RPS25	-9996.0
RPL12	-9789.0
RPL23	-9573.0
RPL18	-9396.0
RPL10L	-9192.0
SPCS1	-9174.0
RPL13	-9165.0
SRP72	-9160.0
RPL10A	-8981.0
SEC61B	-8931.0
RPS13	-8885.0
RPL24	-8697.0
RPS26	-8630.0
RPS6	-8578.0
RPL41	-8474.0
RPS28	-8280.0
RPL13A	-8267.5
RPL14	-8156.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL29	-10734.0
RPS12	-10480.0
RPS25	-9996.0
RPL12	-9789.0
RPL23	-9573.0
RPL18	-9396.0
RPL10L	-9192.0
SPCS1	-9174.0
RPL13	-9165.0
SRP72	-9160.0
RPL10A	-8981.0
SEC61B	-8931.0
RPS13	-8885.0
RPL24	-8697.0
RPS26	-8630.0
RPS6	-8578.0
RPL41	-8474.0
RPS28	-8280.0
RPL13A	-8267.5
RPL14	-8156.0
RPL11	-8150.0
RPL4	-8026.0
RPL7	-8006.0
RPL39L	-7836.0
FAU	-7687.0
RPL34	-7413.0
RPS15A	-7332.0
RPL5	-7169.0
RPSA	-6914.0
RPL36AL	-6833.5
SRPRA	-6789.0
RPL37	-6752.0
RPN1	-6622.0
RPLP0	-6587.0
RPL23A	-6481.0
RPL35A	-6473.0
RPL21	-6325.0
RPL22L1	-6284.0
RPS3A	-6158.0
RPL17	-5981.0
SSR2	-5934.0
RPL27A	-5715.0
RPS24	-5677.0
RPL18A	-5525.0
RPS18	-5357.0
RPL35	-5265.0
SPCS2	-5141.0
RPL8	-5017.0
SRP14	-4955.0
RPS20	-4837.0
SRP9	-4687.0
RPLP2	-4592.0
SEC11A	-4435.0
SRP19	-4414.0
UBA52	-4361.0
RPL28	-4300.0
RPS10	-4220.0
RPS11	-4189.0
RPS5	-3903.0
RPL36	-3867.0
SRP54	-3691.0
RPLP1	-3490.0
RPL15	-3478.0
RPS29	-3289.0
RPL19	-3065.0
SEC11C	-2799.0
RPL9	-2640.0
RPS16	-2594.0
RPL30	-2386.0
RPS15	-2337.0
RPL6	-2141.0
RPL3	-1846.0
RPS2	-1664.0
RPS27A	-1544.0
RPL38	-1357.0
RPS8	-1326.0
RPS23	-1205.0
RPL37A	-1087.0
RPS21	-811.0
TRAM1	-734.0
SPCS3	-152.0
RPS9	-121.0
RPL32	63.0
SRPRB	213.0
SEC61A1	385.0
RPN2	1748.0
RPS7	1873.0
RPL26L1	3302.0
RPL27	3305.0
SEC61G	3332.0
SSR3	3513.0
RPL26	3766.0
SRP68	3852.0
RPS27L	3876.0
RPL7A	4313.0
SSR1	4480.0
RPL31	7031.0
RPS3	7084.0
RPS27	7437.0
DDOST	7512.0
RPL22	7534.0
RPS14	7712.0
RPS19	7721.0
SEC61A2	8187.0
RPL3L	9685.0

---

REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS

REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS

	1364
set	REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS
setSize	161
pANOVA	7.36e-08
s.dist	-0.246
p.adjustANOVA	4.37e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL29	-10734
RPS12	-10480
RPS25	-9996
MAGOH	-9876
RPL12	-9789
UBB	-9702
RPL23	-9573
RPL18	-9396
PSMC4	-9362
RPL10L	-9192
LHX2	-9171
RPL13	-9165
RPL10A	-8981
RPS13	-8885
PSMA8	-8792
RPL24	-8697
RPS26	-8630
RPS6	-8578
RPL41	-8474
RBM8A	-8468

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL29	-10734.0
RPS12	-10480.0
RPS25	-9996.0
MAGOH	-9876.0
RPL12	-9789.0
UBB	-9702.0
RPL23	-9573.0
RPL18	-9396.0
PSMC4	-9362.0
RPL10L	-9192.0
LHX2	-9171.0
RPL13	-9165.0
RPL10A	-8981.0
RPS13	-8885.0
PSMA8	-8792.0
RPL24	-8697.0
RPS26	-8630.0
RPS6	-8578.0
RPL41	-8474.0
RBM8A	-8468.0
ETF1	-8311.0
RPS28	-8280.0
RPL13A	-8267.5
RPL14	-8156.0
RPL11	-8150.0
RPL4	-8026.0
RPL7	-8006.0
LHX9	-8002.0
UBC	-7974.0
PSMD12	-7843.0
RPL39L	-7836.0
FAU	-7687.0
PSMB10	-7431.0
PSMC5	-7419.0
RPL34	-7413.0
RPS15A	-7332.0
ELOC	-7318.0
RPL5	-7169.0
LHX3	-7113.0
PSMB4	-7098.0
RPSA	-6914.0
RPL36AL	-6833.5
PSME4	-6754.0
RPL37	-6752.0
RPLP0	-6587.0
LHX4	-6583.0
RPL23A	-6481.0
RPL35A	-6473.0
RPL21	-6325.0
RPL22L1	-6284.0
RPS3A	-6158.0
PSMC2	-6092.0
PSME2	-6084.0
SLIT2	-6063.0
PSMA3	-5986.0
RPL17	-5981.0
PSMB8	-5844.0
RPL27A	-5715.0
RPS24	-5677.0
RPL18A	-5525.0
RNPS1	-5489.0
RPS18	-5357.0
RPL35	-5265.0
NCBP2	-5148.0
RPL8	-5017.0
RPS20	-4837.0
ELOB	-4810.0
RPLP2	-4592.0
GSPT1	-4445.0
PSMA5	-4438.0
UBA52	-4361.0
PSMD11	-4325.0
RPL28	-4300.0
PSMD5	-4244.0
RPS10	-4220.0
RPS11	-4189.0
CASC3	-4102.0
PSMD9	-3987.0
RPS5	-3903.0
RPL36	-3867.0
RPLP1	-3490.0
RPL15	-3478.0
PSMA6	-3425.0
RPS29	-3289.0
EIF4G1	-3228.0
RBX1	-3122.0
ROBO2	-3112.0
PSMC1	-3076.0
RPL19	-3065.0
PSME3	-3024.0
PSMB9	-2972.0
ROBO1	-2938.0
ROBO3	-2930.0
RPL9	-2640.0
RPS16	-2594.0
RPL30	-2386.0
RPS15	-2337.0
RPL6	-2141.0
PSMD1	-2120.0
RPL3	-1846.0
PSMB5	-1772.0
RPS2	-1664.0
SLIT1	-1546.0
PSMA1	-1545.0
RPS27A	-1544.0
PSMB3	-1361.0
RPL38	-1357.0
RPS8	-1326.0
RPS23	-1205.0
RPL37A	-1087.0
UPF3A	-824.0
RPS21	-811.0
PSME1	-658.0
PABPC1	-486.0
NCBP1	-381.0
RPS9	-121.0
SEM1	-1.0
RPL32	63.0
UPF2	298.0
PSMD8	315.0
LDB1	472.0
PSMA7	942.0
PSMA2	1059.0
PSMD7	1158.0
PSMB2	1566.0
RPS7	1873.0
CUL2	2205.0
MSI1	2338.0
PSMD14	2369.0
PSMC3	2777.0
ISL1	2851.0
RPL26L1	3302.0
PSMD13	3304.0
RPL27	3305.0
PSMB7	3558.0
PSMD4	3642.0
PSMD2	3699.0
RPL26	3766.0
RPS27L	3876.0
PSMA4	4073.0
RPL7A	4313.0
PSMC6	4442.0
PSMD6	4479.0
MAGOHB	4952.0
DAG1	5020.0
PSMB6	5196.0
PSMF1	5201.0
PSMB1	5414.0
USP33	5663.0
EIF4A3	5714.0
HOXA2	6767.0
RPL31	7031.0
RPS3	7084.0
RPS27	7437.0
RPL22	7534.0
RPS14	7712.0
RPS19	7721.0
PSMD3	8120.0
ZSWIM8	9560.0
RPL3L	9685.0
PSMB11	9803.0

---

REACTOME_EUKARYOTIC_TRANSLATION_INITIATION

REACTOME_EUKARYOTIC_TRANSLATION_INITIATION

	1149
set	REACTOME_EUKARYOTIC_TRANSLATION_INITIATION
setSize	110
pANOVA	7.99e-08
s.dist	-0.296
p.adjustANOVA	4.37e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL29	-10734.0
RPS12	-10480.0
RPS25	-9996.0
RPL12	-9789.0
RPL23	-9573.0
RPL18	-9396.0
RPL10L	-9192.0
RPL13	-9165.0
EIF3J	-9090.0
RPL10A	-8981.0
RPS13	-8885.0
RPL24	-8697.0
RPS26	-8630.0
RPS6	-8578.0
RPL41	-8474.0
RPS28	-8280.0
RPL13A	-8267.5
EIF4A2	-8210.0
RPL14	-8156.0
RPL11	-8150.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL29	-10734.0
RPS12	-10480.0
RPS25	-9996.0
RPL12	-9789.0
RPL23	-9573.0
RPL18	-9396.0
RPL10L	-9192.0
RPL13	-9165.0
EIF3J	-9090.0
RPL10A	-8981.0
RPS13	-8885.0
RPL24	-8697.0
RPS26	-8630.0
RPS6	-8578.0
RPL41	-8474.0
RPS28	-8280.0
RPL13A	-8267.5
EIF4A2	-8210.0
RPL14	-8156.0
RPL11	-8150.0
RPL4	-8026.0
RPL7	-8006.0
RPL39L	-7836.0
EIF2S1	-7708.0
FAU	-7687.0
RPL34	-7413.0
RPS15A	-7332.0
EIF3F	-7308.0
EIF4H	-7179.0
RPL5	-7169.0
RPSA	-6914.0
EIF4A1	-6854.0
RPL36AL	-6833.5
RPL37	-6752.0
RPLP0	-6587.0
EIF2S2	-6580.0
RPL23A	-6481.0
RPL35A	-6473.0
EIF2B2	-6405.0
RPL21	-6325.0
EIF5B	-6305.0
RPL22L1	-6284.0
RPS3A	-6158.0
RPL17	-5981.0
RPL27A	-5715.0
RPS24	-5677.0
RPL18A	-5525.0
EIF3D	-5426.0
RPS18	-5357.0
EIF2B3	-5284.0
RPL35	-5265.0
RPL8	-5017.0
RPS20	-4837.0
RPLP2	-4592.0
UBA52	-4361.0
RPL28	-4300.0
RPS10	-4220.0
RPS11	-4189.0
EIF2B1	-3939.0
RPS5	-3903.0
RPL36	-3867.0
RPLP1	-3490.0
RPL15	-3478.0
EIF2B4	-3323.0
RPS29	-3289.0
EIF4G1	-3228.0
RPL19	-3065.0
RPL9	-2640.0
RPS16	-2594.0
RPL30	-2386.0
RPS15	-2337.0
EIF3H	-2264.0
RPL6	-2141.0
RPL3	-1846.0
RPS2	-1664.0
RPS27A	-1544.0
RPL38	-1357.0
RPS8	-1326.0
RPS23	-1205.0
RPL37A	-1087.0
EIF3K	-868.0
RPS21	-811.0
EIF4B	-617.0
PABPC1	-486.0
EIF4EBP1	-165.0
RPS9	-121.0
EIF5	-46.0
RPL32	63.0
EIF3I	364.0
EIF3L	931.0
EIF3G	1836.0
RPS7	1873.0
EIF3M	2569.0
EIF4E	3258.0
RPL26L1	3302.0
RPL27	3305.0
RPL26	3766.0
RPS27L	3876.0
RPL7A	4313.0
EIF3A	6716.0
RPL31	7031.0
RPS3	7084.0
EIF2B5	7100.0
RPS27	7437.0
RPL22	7534.0
RPS14	7712.0
RPS19	7721.0
EIF3E	8167.0
EIF3B	8505.0
RPL3L	9685.0

---

REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION

REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION

	151
set	REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION
setSize	87
pANOVA	1.44e-07
s.dist	-0.326
p.adjustANOVA	5.01e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL29	-10734.0
RPS12	-10480.0
EEF1G	-10100.0
RPS25	-9996.0
RPL12	-9789.0
RPL23	-9573.0
RPL18	-9396.0
RPL10L	-9192.0
RPL13	-9165.0
RPL10A	-8981.0
RPS13	-8885.0
RPL24	-8697.0
RPS26	-8630.0
RPS6	-8578.0
RPL41	-8474.0
RPS28	-8280.0
RPL13A	-8267.5
RPL14	-8156.0
RPL11	-8150.0
RPL4	-8026.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL29	-10734.0
RPS12	-10480.0
EEF1G	-10100.0
RPS25	-9996.0
RPL12	-9789.0
RPL23	-9573.0
RPL18	-9396.0
RPL10L	-9192.0
RPL13	-9165.0
RPL10A	-8981.0
RPS13	-8885.0
RPL24	-8697.0
RPS26	-8630.0
RPS6	-8578.0
RPL41	-8474.0
RPS28	-8280.0
RPL13A	-8267.5
RPL14	-8156.0
RPL11	-8150.0
RPL4	-8026.0
RPL7	-8006.0
RPL39L	-7836.0
FAU	-7687.0
RPL34	-7413.0
RPS15A	-7332.0
RPL5	-7169.0
RPSA	-6914.0
RPL36AL	-6833.5
RPL37	-6752.0
RPLP0	-6587.0
RPL23A	-6481.0
RPL35A	-6473.0
RPL21	-6325.0
EEF1B2	-6321.0
RPL22L1	-6284.0
RPS3A	-6158.0
RPL17	-5981.0
RPL27A	-5715.0
RPS24	-5677.0
RPL18A	-5525.0
RPS18	-5357.0
RPL35	-5265.0
RPL8	-5017.0
RPS20	-4837.0
RPLP2	-4592.0
EEF1A1	-4419.0
UBA52	-4361.0
RPL28	-4300.0
RPS10	-4220.0
RPS11	-4189.0
RPS5	-3903.0
RPL36	-3867.0
RPLP1	-3490.0
RPL15	-3478.0
RPS29	-3289.0
RPL19	-3065.0
RPL9	-2640.0
RPS16	-2594.0
RPL30	-2386.0
RPS15	-2337.0
RPL6	-2141.0
RPL3	-1846.0
RPS2	-1664.0
RPS27A	-1544.0
RPL38	-1357.0
RPS8	-1326.0
RPS23	-1205.0
RPL37A	-1087.0
RPS21	-811.0
RPS9	-121.0
RPL32	63.0
EEF1A2	729.0
RPS7	1873.0
RPL26L1	3302.0
RPL27	3305.0
RPL26	3766.0
RPS27L	3876.0
RPL7A	4313.0
EEF2	5833.0
RPL31	7031.0
RPS3	7084.0
RPS27	7437.0
RPL22	7534.0
RPS14	7712.0
RPS19	7721.0
EEF1D	9215.0
RPL3L	9685.0

---

REACTOME_NONSENSE_MEDIATED_DECAY_NMD

REACTOME_NONSENSE_MEDIATED_DECAY_NMD

	1443
set	REACTOME_NONSENSE_MEDIATED_DECAY_NMD
setSize	107
pANOVA	1.53e-07
s.dist	-0.294
p.adjustANOVA	5.01e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL29	-10734.0
RPS12	-10480.0
RPS25	-9996.0
MAGOH	-9876.0
RPL12	-9789.0
RPL23	-9573.0
RPL18	-9396.0
RPL10L	-9192.0
RPL13	-9165.0
RPL10A	-8981.0
RPS13	-8885.0
RPL24	-8697.0
RPS26	-8630.0
RPS6	-8578.0
RPL41	-8474.0
RBM8A	-8468.0
ETF1	-8311.0
RPS28	-8280.0
RPL13A	-8267.5
RPL14	-8156.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL29	-10734.0
RPS12	-10480.0
RPS25	-9996.0
MAGOH	-9876.0
RPL12	-9789.0
RPL23	-9573.0
RPL18	-9396.0
RPL10L	-9192.0
RPL13	-9165.0
RPL10A	-8981.0
RPS13	-8885.0
RPL24	-8697.0
RPS26	-8630.0
RPS6	-8578.0
RPL41	-8474.0
RBM8A	-8468.0
ETF1	-8311.0
RPS28	-8280.0
RPL13A	-8267.5
RPL14	-8156.0
RPL11	-8150.0
RPL4	-8026.0
RPL7	-8006.0
RPL39L	-7836.0
FAU	-7687.0
RPL34	-7413.0
RPS15A	-7332.0
RPL5	-7169.0
RPSA	-6914.0
RPL36AL	-6833.5
RPL37	-6752.0
RPLP0	-6587.0
RPL23A	-6481.0
RPL35A	-6473.0
RPL21	-6325.0
RPL22L1	-6284.0
RPS3A	-6158.0
RPL17	-5981.0
SMG6	-5755.0
RPL27A	-5715.0
RPS24	-5677.0
RPL18A	-5525.0
RNPS1	-5489.0
RPS18	-5357.0
RPL35	-5265.0
NCBP2	-5148.0
RPL8	-5017.0
RPS20	-4837.0
RPLP2	-4592.0
GSPT1	-4445.0
UBA52	-4361.0
RPL28	-4300.0
RPS10	-4220.0
RPS11	-4189.0
CASC3	-4102.0
RPS5	-3903.0
RPL36	-3867.0
PPP2R2A	-3614.0
RPLP1	-3490.0
RPL15	-3478.0
RPS29	-3289.0
EIF4G1	-3228.0
RPL19	-3065.0
RPL9	-2640.0
RPS16	-2594.0
PPP2CA	-2430.0
RPL30	-2386.0
RPS15	-2337.0
RPL6	-2141.0
SMG5	-2075.0
RPL3	-1846.0
PNRC2	-1844.0
RPS2	-1664.0
RPS27A	-1544.0
RPL38	-1357.0
RPS8	-1326.0
RPS23	-1205.0
RPL37A	-1087.0
SMG9	-880.0
UPF3A	-824.0
RPS21	-811.0
PABPC1	-486.0
NCBP1	-381.0
RPS9	-121.0
RPL32	63.0
UPF2	298.0
SMG7	366.0
SMG1	528.0
DCP1A	601.0
PPP2R1A	1222.0
RPS7	1873.0
RPL26L1	3302.0
RPL27	3305.0
RPL26	3766.0
RPS27L	3876.0
RPL7A	4313.0
MAGOHB	4952.0
SMG8	5658.0
EIF4A3	5714.0
RPL31	7031.0
RPS3	7084.0
RPS27	7437.0
RPL22	7534.0
RPS14	7712.0
RPS19	7721.0
UPF1	8920.0
RPL3L	9685.0

---

REACTOME_METABOLISM_OF_RNA

REACTOME_METABOLISM_OF_RNA

	1313
set	REACTOME_METABOLISM_OF_RNA
setSize	675
pANOVA	2.69e-07
s.dist	-0.116
p.adjustANOVA	7.36e-05

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL29	-10734
TYW1	-10714
RPS12	-10480
LSM8	-10416
THOC3	-10330
ZCRB1	-10186
NUP50	-10150
RPPH1	-10070
TRNT1	-10066
RRP9	-10014
SRSF10	-10008
RPS25	-9996
HSPA1A	-9954
MAGOH	-9876
CLP1	-9852
UTP11	-9836
RPL12	-9789
HNRNPD	-9773
RBM39	-9754
UBB	-9702

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL29	-10734.0
TYW1	-10714.0
RPS12	-10480.0
LSM8	-10416.0
THOC3	-10330.0
ZCRB1	-10186.0
NUP50	-10150.0
RPPH1	-10070.0
TRNT1	-10066.0
RRP9	-10014.0
SRSF10	-10008.0
RPS25	-9996.0
HSPA1A	-9954.0
MAGOH	-9876.0
CLP1	-9852.0
UTP11	-9836.0
RPL12	-9789.0
HNRNPD	-9773.0
RBM39	-9754.0
UBB	-9702.0
RPL23	-9573.0
PHF5A	-9539.0
HSPA8	-9533.0
UTP4	-9521.0
RRP36	-9485.0
CCNH	-9414.0
POLR2K	-9413.0
RPL18	-9396.0
PRCC	-9379.0
PSMC4	-9362.0
IMP3	-9307.0
BYSL	-9275.0
RPL10L	-9192.0
RPL13	-9165.0
APOBEC3B	-9115.0
RPL10A	-8981.0
IGF2BP2	-8900.0
RPS13	-8885.0
SF3B4	-8852.0
PSMA8	-8792.0
USP39	-8710.0
RPL24	-8697.0
RPS26	-8630.0
LTV1	-8598.0
RPS6	-8578.0
TRMT6	-8534.0
HNRNPA1	-8516.0
TRMT10C	-8497.0
GEMIN5	-8488.0
RPL41	-8474.0
RBM8A	-8468.0
NUP42	-8372.0
NUP153	-8324.0
ETF1	-8311.0
TRMT12	-8295.0
CNOT8	-8284.0
RPS28	-8280.0
SLBP	-8275.0
RPL13A	-8267.5
FUS	-8265.0
APOBEC3C	-8257.0
DDX21	-8215.0
EIF4A2	-8210.0
RPL14	-8156.0
RPL11	-8150.0
AAAS	-8141.0
SDE2	-8108.0
GEMIN2	-8084.0
HNRNPU	-8052.0
POP1	-8029.0
RPL4	-8026.0
RPL7	-8006.0
YBX1	-8000.0
UTP6	-7983.0
UBC	-7974.0
PSMD12	-7843.0
RPL39L	-7836.0
NXT1	-7822.0
MPHOSPH10	-7780.0
SNRPD1	-7753.0
DCPS	-7732.0
GTF2F1	-7689.0
FAU	-7687.0
ERI1	-7618.0
LUC7L3	-7601.0
WDR75	-7582.0
DDX6	-7561.0
TRMT10A	-7479.0
PSMB10	-7431.0
PSMC5	-7419.0
RPL34	-7413.0
POLR2L	-7397.0
POLR2D	-7349.0
TRMT1	-7343.0
RPS15A	-7332.0
PABPN1	-7259.0
DCAF13	-7188.0
RPL5	-7169.0
PHAX	-7141.0
TNPO1	-7140.0
XPOT	-7130.0
POP5	-7128.0
PSMB4	-7098.0
EXOSC5	-7041.0
CRNKL1	-7038.0
PUS7	-6973.0
UTP20	-6969.0
EDC3	-6968.0
RPSA	-6914.0
EIF4A1	-6854.0
RPL36AL	-6833.5
RIOK3	-6831.0
RBM28	-6765.0
PSME4	-6754.0
RPL37	-6752.0
FTSJ3	-6656.0
FAM98B	-6604.0
RPLP0	-6587.0
LSM3	-6555.0
YWHAZ	-6541.0
HNRNPH1	-6516.0
POLR2I	-6513.0
RPL23A	-6481.0
TP53RK	-6478.0
RPL35A	-6473.0
PCF11	-6466.0
ANP32A	-6431.0
HNRNPL	-6356.0
RPL21	-6325.0
SNW1	-6319.0
MPHOSPH6	-6314.0
RPL22L1	-6284.0
MAPK14	-6253.0
SNUPN	-6215.0
PAIP1	-6188.0
DDX39A	-6172.0
RPS3A	-6158.0
HNRNPC	-6117.0
NUP35	-6110.0
IGF2BP3	-6096.0
PSMC2	-6092.0
PSME2	-6084.0
HNRNPR	-6070.0
POM121	-6050.0
HNRNPK	-6034.0
NSRP1	-6026.0
SRSF7	-6003.0
TRA2B	-5991.0
PSMA3	-5986.0
RPL17	-5981.0
CCDC12	-5942.0
WTAP	-5930.0
PNO1	-5905.0
GEMIN7	-5904.0
PRPF4	-5874.0
PSMB8	-5844.0
SYMPK	-5817.0
FYTTD1	-5794.0
SNRNP25	-5761.0
SMG6	-5755.0
GTF2H5	-5748.0
RPL27A	-5715.0
NOP58	-5712.0
GAR1	-5682.0
RPS24	-5677.0
NOL6	-5586.0
RPL18A	-5525.0
RNPS1	-5489.0
C2orf49	-5472.0
PPWD1	-5440.0
NUP205	-5439.0
RPS18	-5357.0
NOL11	-5333.0
SRSF12	-5324.0
RAE1	-5266.0
RPL35	-5265.0
DUS2	-5240.0
SET	-5225.0
SNRNP48	-5190.0
RBM22	-5167.0
NCBP2	-5148.0
NCL	-5085.0
RPL8	-5017.0
ADAT1	-4989.0
XRN2	-4977.0
CWC22	-4970.0
PPIL4	-4960.0
PDCD11	-4902.0
DCP2	-4848.0
RPS20	-4837.0
SRSF8	-4788.0
APOBEC3A	-4744.0
NOL12	-4700.0
NUP37	-4666.0
NUP155	-4621.0
TYW3	-4615.0
RBM25	-4608.0
RPLP2	-4592.0
SNRPB2	-4546.0
NUP133	-4483.0
GPATCH1	-4457.0
TGS1	-4456.0
UTP3	-4446.0
GSPT1	-4445.0
PSMA5	-4438.0
SRSF1	-4423.0
SRSF2	-4420.0
TRMT5	-4403.0
UBA52	-4361.0
U2AF1L4	-4338.0
SF3B2	-4328.0
PSMD11	-4325.0
RTCB	-4307.0
RPL28	-4300.0
RPP30	-4260.0
RPP25	-4250.0
PSMD5	-4244.0
SF3B6	-4239.0
RPS10	-4220.0
ALKBH8	-4215.0
PUS1	-4211.0
HNRNPA3	-4208.0
APOBEC1	-4201.0
RPS11	-4189.0
DDX20	-4180.0
CDC5L	-4179.0
RBM7	-4114.0
CASC3	-4102.0
PCBP2	-4088.0
EXOSC3	-4085.0
IGF2BP1	-4064.0
ISG20L2	-4058.0
ZNF473	-4001.0
PSMD9	-3987.0
MTO1	-3951.0
TRMT9B	-3949.0
POLR2C	-3916.0
RPS5	-3903.0
ZBTB8OS	-3885.0
TSEN15	-3873.0
RPL36	-3867.0
EFTUD2	-3811.0
EXOSC8	-3710.0
PRPF40A	-3703.0
RRP1	-3697.0
CDK7	-3687.0
HSPB1	-3666.0
CSNK1E	-3631.0
TRMT11	-3627.0
U2SURP	-3622.0
PPP2R2A	-3614.0
LSM6	-3611.0
UBL5	-3610.0
GTF2H1	-3579.0
WBP11	-3550.0
CSTF1	-3526.0
RPLP1	-3490.0
RPL15	-3478.0
BUD31	-3448.0
SNRNP27	-3441.0
PSMA6	-3425.0
PAN3	-3419.0
OSGEP	-3378.0
TRMT112	-3360.0
EPRS1	-3352.0
RIOK2	-3325.0
THOC6	-3296.0
CLNS1A	-3294.0
WDR3	-3291.0
RPS29	-3289.0
THUMPD1	-3285.0
EXOSC7	-3252.0
NXF1	-3239.0
EIF4G1	-3228.0
PTBP1	-3213.0
A1CF	-3186.0
EXOSC1	-3185.0
SNRPA	-3127.0
PRKRIP1	-3079.0
PSMC1	-3076.0
CPSF3	-3075.0
RPL19	-3065.0
PSME3	-3024.0
ACIN1	-3021.0
PSMB9	-2972.0
CNOT2	-2903.0
SNRPF	-2877.0
PLRG1	-2857.0
WDR36	-2844.0
LSM7	-2795.0
POM121C	-2759.0
TRMT13	-2735.0
SNRPN	-2707.0
DDX5	-2682.0
RPL9	-2640.0
MAPKAPK2	-2623.0
PPIH	-2611.0
RPS16	-2594.0
RPP40	-2575.0
WDR77	-2540.0
NUP43	-2489.0
UTP18	-2482.0
RPP38	-2473.0
ZFP36L1	-2449.0
LSM1	-2444.0
KRR1	-2432.0
PPP2CA	-2430.0
MRM1	-2429.0
RPL30	-2386.0
SNRPA1	-2380.0
HNRNPA2B1	-2347.0
RPS15	-2337.0
ADAT2	-2335.0
GEMIN6	-2333.0
SRSF6	-2316.0
CNOT6L	-2281.0
SNRPD2	-2280.0
SAP18	-2267.0
C9orf78	-2262.0
RPP21	-2207.0
NOP56	-2196.0
CNOT10	-2175.0
PATL1	-2157.0
RPL6	-2141.0
HNRNPF	-2138.0
GNL3	-2134.0
NAT10	-2123.0
PSMD1	-2120.0
CHTOP	-2110.0
SMG5	-2075.0
SRRM1	-2062.0
GTPBP3	-2048.0
CPSF2	-2027.0
NDC1	-1937.0
SF3B3	-1903.0
RPL3	-1846.0
PNRC2	-1844.0
DHX35	-1818.0
PSMB5	-1772.0
SRSF4	-1744.0
LENG1	-1743.0
LSM4	-1728.0
CTU1	-1688.0
RPS2	-1664.0
CWC27	-1640.0
CNOT11	-1620.0
CWC15	-1613.0
SRSF3	-1573.0
PSMA1	-1545.0
RPS27A	-1544.0
WDR12	-1535.0
SMU1	-1494.0
CDC40	-1463.0
GTF2H3	-1441.0
MTREX	-1433.0
MRM3	-1400.0
IK	-1388.0
PSMB3	-1361.0
RPL38	-1357.0
PPIG	-1334.0
MNAT1	-1328.0
PPIL1	-1327.0
RPS8	-1326.0
RPS23	-1205.0
RPL37A	-1087.0
PCBP1	-1067.0
NOB1	-975.0
TSEN54	-911.0
SNRPE	-904.0
SMG9	-880.0
UPF3A	-824.0
SNRNP35	-823.0
RPS21	-811.0
DIMT1	-764.0
SMNDC1	-675.0
PSME1	-658.0
POLDIP3	-636.0
EIF4B	-617.0
CDKAL1	-610.0
GTF2F2	-573.0
CNOT7	-558.0
CCAR1	-544.0
PRORP	-496.0
PABPC1	-486.0
DHX9	-483.0
PRPF19	-414.0
CPSF6	-390.0
NCBP1	-381.0
YWHAB	-355.0
NIP7	-336.0
SRRT	-312.0
DDX41	-304.0
METTL3	-235.0
PRMT5	-221.0
PAPOLA	-216.0
DIS3	-214.0
APOBEC4	-198.0
SRSF11	-169.0
SNRPD3	-159.0
RPS9	-121.0
HNRNPM	-103.0
DDX46	-38.0
SEM1	-1.0
TCERG1	0.0
BMS1	9.0
QTRT1	25.0
TUT7	52.0
FCF1	60.0
RPL32	63.0
NUP85	69.0
NUP214	74.0
POLR2B	117.0
CNOT9	125.0
WDR43	128.0
LSM2	175.0
CNOT6	187.0
TYW5	259.0
NT5C3B	262.0
RPP14	284.0
HEATR1	297.0
UPF2	298.0
PSMD8	315.0
NSUN6	346.0
PDCD7	365.0
SMG7	366.0
KHSRP	419.0
LSM5	425.0
METTL1	459.0
MFAP1	473.0
EMG1	480.0
FIP1L1	484.0
C1D	504.0
BUD13	517.0
SMG1	528.0
SF3A3	534.0
PAN2	562.0
TRMT61B	596.0
DCP1A	601.0
DDX1	634.0
PRKCD	639.0
SNU13	663.0
THOC7	664.0
SNRNP40	666.0
TXNL4A	700.0
NUDT21	703.0
ZNF830	739.0
UTP25	761.0
BCAS2	783.0
PRPF31	807.0
NHP2	857.0
POP4	919.0
POLR2G	936.0
PSMA7	942.0
PUS3	943.0
DCP1B	995.0
FAM32A	1024.0
CTU2	1031.0
PPIL3	1035.0
PSMA2	1059.0
PSMD7	1158.0
PPP2R1A	1222.0
SNRPC	1293.0
CNOT4	1474.0
GEMIN4	1547.0
NUP107	1548.0
RBM42	1561.0
PSMB2	1566.0
TNFSF13	1598.0
SF3A1	1614.0
DHX15	1616.0
CPSF7	1694.0
SF3A2	1701.0
CWF19L2	1721.0
XPO1	1743.0
ZC3H11A	1841.0
RTRAF	1847.0
RPS7	1873.0
ALYREF	1883.0
ZMAT5	1886.0
NSUN4	1899.0
RNMT	1929.0
SF3B1	1931.0
THOC1	1952.0
RNGTT	1953.0
NOP2	1958.0
LSM11	1965.0
CSTF2T	2008.0
PELP1	2019.0
SEH1L	2049.0
POLR2E	2087.0
WDR70	2168.0
DHX38	2217.0
SLU7	2221.0
RBM17	2245.0
PPP1R8	2249.0
EXOSC9	2285.0
CWC25	2295.0
MTERF4	2335.0
PSMD14	2369.0
DDX47	2392.0
EBNA1BP2	2422.0
SRSF5	2434.0
UTP15	2499.0
RNPC3	2516.0
QTRT2	2524.0
SNIP1	2613.0
CNOT3	2638.0
HBS1L	2660.0
GTF2H4	2687.0
NOC4L	2726.0
NUP88	2756.0
PSMC3	2777.0
POLR2H	2784.0
NUP188	2838.0
WDR46	2848.0
NUP160	2878.0
XRN1	2951.0
MAPK11	2972.0
DNAJC8	2994.0
TUT4	2996.0
SNRPG	3043.0
LSM10	3090.0
SKIC3	3109.0
EIF4E	3258.0
PRPF6	3293.0
SNRNP70	3296.0
RPL26L1	3302.0
PSMD13	3304.0
RPL27	3305.0
TPRKB	3325.0
SF3B5	3487.0
RBM5	3493.0
PPIL2	3526.0
TPR	3550.0
PSMB7	3558.0
DDX52	3578.0
THOC5	3615.0
PSMD4	3642.0
THADA	3645.0
PSMD2	3699.0
PRKCA	3721.0
ZMAT2	3725.0
SARNP	3756.0
RPL26	3766.0
SYF2	3789.0
RPS27L	3876.0
SRSF9	3890.0
NUP98	3900.0
CACTIN	3915.0
RIOK1	3928.0
ADAT3	3932.0
SUGP1	4056.0
PSMA4	4073.0
GCFC2	4091.0
TNKS1BP1	4112.0
DHX16	4127.0
TRIT1	4229.0
RPL7A	4313.0
PARN	4336.0
MRM2	4371.0
NOP10	4382.0
CTNNBL1	4392.0
RAN	4428.0
PSMC6	4442.0
TSEN34	4443.0
LCMT2	4474.0
PSMD6	4479.0
ISY1	4486.0
POP7	4545.0
TFIP11	4558.0
THG1L	4587.0
DDX23	4618.0
CNOT1	4659.0
SF1	4672.0
FBL	4725.0
TFB1M	4733.0
IMP4	4740.0
DDX42	4751.0
MAGOHB	4952.0
NUP54	4974.0
GLE1	5026.0
BUD23	5056.0
DHX8	5135.0
TRDMT1	5142.0
ERCC3	5144.0
ELAVL1	5166.0
NOL9	5174.0
PSMB6	5196.0
PSMF1	5201.0
DDX49	5206.0
PES1	5213.0
PSMB1	5414.0
NUP93	5467.0
TSEN2	5476.0
PRPF38A	5504.0
TSR1	5543.0
PRPF3	5593.0
NSUN2	5613.0
SUPT5H	5619.0
SMG8	5658.0
EIF4A3	5714.0
NUP210	5745.0
METTL14	5816.0
NUP58	5846.0
WDR33	5892.0
DDX39B	5923.0
TRMU	6043.0
NOP14	6055.0
EXOSC4	6081.0
BOP1	6131.0
PNN	6317.0
CSTF3	6357.0
RCL1	6429.0
ADAR	6532.0
XAB2	6590.0
POLR2F	6656.0
CSNK1D	6698.0
SNRPB	6751.0
PPIE	6772.0
PUF60	6792.0
ZFP36	6793.0
CPSF4	6824.0
SMN1	6830.5
SMN2	6830.5
AQR	6986.0
RPL31	7031.0
ERCC2	7083.0
RPS3	7084.0
PWP2	7107.0
CPSF1	7172.0
TSR3	7198.0
PRPF18	7277.0
RANBP2	7396.0
RPS27	7437.0
SNRNP200	7453.0
NUP62	7457.0
RPL22	7534.0
ADARB1	7539.0
RPS14	7712.0
RPS19	7721.0
POLR2A	7751.0
TRMT61A	7762.0
AKT1	7830.0
YJU2	7888.0
EXOSC2	7893.0
SKIC2	7962.0
U2AF2	7974.0
PRPF8	8031.0
PSMD3	8120.0
WBP4	8241.0
APOBEC3H	8371.0
SART1	8411.0
SEC13	8482.0
WDR18	8495.0
SENP3	8517.0
ELAC2	8529.0
WDR4	8588.0
URM1	8686.0
UPF1	8920.0
EXOSC6	9038.0
TEX10	9054.0
TBL3	9211.0
DHX37	9292.0
CHERP	9309.0
UTP14C	9487.0
SRRM2	9499.0
SKIC8	9622.0
RPL3L	9685.0
POLR2J	9748.0
PSMB11	9803.0
EDC4	9939.0
EXOSC10	10158.0
TRMT44	10436.0
RRP7A	10441.0
APOBEC2	10718.0

---

REACTOME_INFLUENZA_INFECTION

REACTOME_INFLUENZA_INFECTION

	228
set	REACTOME_INFLUENZA_INFECTION
setSize	149
pANOVA	4.49e-07
s.dist	-0.239
p.adjustANOVA	0.000105

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL29	-10734
RPS12	-10480
NUP50	-10150
RPS25	-9996
HSPA1A	-9954
CLTA	-9790
RPL12	-9789
RPL23	-9573
POLR2K	-9413
RPL18	-9396
RPL10L	-9192
RPL13	-9165
RPL10A	-8981
RPS13	-8885
RPL24	-8697
RPS26	-8630
RPS6	-8578
RPL41	-8474
NUP42	-8372
NUP153	-8324

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL29	-10734.0
RPS12	-10480.0
NUP50	-10150.0
RPS25	-9996.0
HSPA1A	-9954.0
CLTA	-9790.0
RPL12	-9789.0
RPL23	-9573.0
POLR2K	-9413.0
RPL18	-9396.0
RPL10L	-9192.0
RPL13	-9165.0
RPL10A	-8981.0
RPS13	-8885.0
RPL24	-8697.0
RPS26	-8630.0
RPS6	-8578.0
RPL41	-8474.0
NUP42	-8372.0
NUP153	-8324.0
RPS28	-8280.0
CALR	-8269.0
RPL13A	-8267.5
RPL14	-8156.0
RPL11	-8150.0
AAAS	-8141.0
RPL4	-8026.0
RPL7	-8006.0
RPL39L	-7836.0
GTF2F1	-7689.0
FAU	-7687.0
RPL34	-7413.0
POLR2L	-7397.0
POLR2D	-7349.0
RPS15A	-7332.0
PABPN1	-7259.0
KPNA7	-7191.0
RPL5	-7169.0
KPNA5	-6957.0
RPSA	-6914.0
RPL36AL	-6833.5
RPL37	-6752.0
RPLP0	-6587.0
POLR2I	-6513.0
RPL23A	-6481.0
RPL35A	-6473.0
RPL21	-6325.0
RPL22L1	-6284.0
RPS3A	-6158.0
NUP35	-6110.0
POM121	-6050.0
HSP90AA1	-6002.0
RPL17	-5981.0
KPNA2	-5929.0
RPL27A	-5715.0
KPNB1	-5688.0
RPS24	-5677.0
RPL18A	-5525.0
NUP205	-5439.0
CANX	-5437.0
RPS18	-5357.0
RAE1	-5266.0
RPL35	-5265.0
RPL8	-5017.0
RPS20	-4837.0
NUP37	-4666.0
NUP155	-4621.0
RPLP2	-4592.0
ISG15	-4511.0
CLTC	-4494.0
NUP133	-4483.0
UBA52	-4361.0
KPNA1	-4347.0
RPL28	-4300.0
RPS10	-4220.0
RPS11	-4189.0
POLR2C	-3916.0
RPS5	-3903.0
RPL36	-3867.0
RPLP1	-3490.0
RPL15	-3478.0
RPS29	-3289.0
RPL19	-3065.0
POM121C	-2759.0
KPNA4	-2708.0
RPL9	-2640.0
RPS16	-2594.0
NUP43	-2489.0
RPL30	-2386.0
RPS15	-2337.0
RPL6	-2141.0
KPNA3	-2071.0
NDC1	-1937.0
RPL3	-1846.0
EIF2AK2	-1726.0
RPS2	-1664.0
RPS27A	-1544.0
RPL38	-1357.0
RPS8	-1326.0
GRSF1	-1228.0
RPS23	-1205.0
RPL37A	-1087.0
RPS21	-811.0
GTF2F2	-573.0
RPS9	-121.0
RPL32	63.0
NUP85	69.0
NUP214	74.0
POLR2B	117.0
POLR2G	936.0
NUP107	1548.0
XPO1	1743.0
RPS7	1873.0
SEH1L	2049.0
POLR2E	2087.0
IPO5	2474.0
NUP88	2756.0
POLR2H	2784.0
NUP188	2838.0
NUP160	2878.0
RPL26L1	3302.0
RPL27	3305.0
TPR	3550.0
RPL26	3766.0
TGFB1	3769.0
RPS27L	3876.0
NUP98	3900.0
RPL7A	4313.0
RAN	4428.0
NUP54	4974.0
NUP93	5467.0
DNAJC3	5724.0
NUP210	5745.0
NUP58	5846.0
POLR2F	6656.0
CPSF4	6824.0
RPL31	7031.0
RPS3	7084.0
RANBP2	7396.0
RPS27	7437.0
NUP62	7457.0
RPL22	7534.0
RPS14	7712.0
RPS19	7721.0
POLR2A	7751.0
PARP1	8062.0
SEC13	8482.0
RPL3L	9685.0
POLR2J	9748.0

---

REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY

REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY

	1486
set	REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY
setSize	94
pANOVA	7.03e-07
s.dist	-0.296
p.adjustANOVA	0.000144

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL29	-10734.0
RPS12	-10480.0
RPS25	-9996.0
RPL12	-9789.0
RPL23	-9573.0
RPL18	-9396.0
RPL10L	-9192.0
RPL13	-9165.0
RPL10A	-8981.0
RPS13	-8885.0
RPL24	-8697.0
RPS26	-8630.0
RPS6	-8578.0
RPL41	-8474.0
RPS28	-8280.0
RPL13A	-8267.5
RPL14	-8156.0
RPL11	-8150.0
RPL4	-8026.0
RPL7	-8006.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL29	-10734.0
RPS12	-10480.0
RPS25	-9996.0
RPL12	-9789.0
RPL23	-9573.0
RPL18	-9396.0
RPL10L	-9192.0
RPL13	-9165.0
RPL10A	-8981.0
RPS13	-8885.0
RPL24	-8697.0
RPS26	-8630.0
RPS6	-8578.0
RPL41	-8474.0
RPS28	-8280.0
RPL13A	-8267.5
RPL14	-8156.0
RPL11	-8150.0
RPL4	-8026.0
RPL7	-8006.0
RPL39L	-7836.0
EIF2S1	-7708.0
FAU	-7687.0
RPL34	-7413.0
RPS15A	-7332.0
RPL5	-7169.0
RPSA	-6914.0
RPL36AL	-6833.5
RPL37	-6752.0
ATF4	-6740.0
RPLP0	-6587.0
EIF2S2	-6580.0
ATF3	-6537.0
RPL23A	-6481.0
RPL35A	-6473.0
RPL21	-6325.0
RPL22L1	-6284.0
RPS3A	-6158.0
RPL17	-5981.0
RPL27A	-5715.0
RPS24	-5677.0
RPL18A	-5525.0
RPS18	-5357.0
RPL35	-5265.0
RPL8	-5017.0
RPS20	-4837.0
RPLP2	-4592.0
UBA52	-4361.0
RPL28	-4300.0
RPS10	-4220.0
RPS11	-4189.0
RPS5	-3903.0
RPL36	-3867.0
ASNS	-3531.0
RPLP1	-3490.0
RPL15	-3478.0
RPS29	-3289.0
RPL19	-3065.0
RPL9	-2640.0
RPS16	-2594.0
RPL30	-2386.0
RPS15	-2337.0
RPL6	-2141.0
RPL3	-1846.0
DDIT3	-1681.0
RPS2	-1664.0
RPS27A	-1544.0
RPL38	-1357.0
RPS8	-1326.0
RPS23	-1205.0
RPL37A	-1087.0
RPS21	-811.0
RPS9	-121.0
ATF2	-41.0
RPL32	63.0
IMPACT	1415.0
RPS7	1873.0
CEBPG	3251.0
RPL26L1	3302.0
RPL27	3305.0
RPL26	3766.0
RPS27L	3876.0
RPL7A	4313.0
EIF2AK4	5421.0
CEBPB	6090.0
RPL31	7031.0
RPS3	7084.0
RPS27	7437.0
GCN1	7532.0
RPL22	7534.0
RPS14	7712.0
RPS19	7721.0
RPL3L	9685.0
TRIB3	9868.0

---

REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM

REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM

	78
set	REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM
setSize	688
pANOVA	1.23e-06
s.dist	-0.108
p.adjustANOVA	0.000223

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IFNA7	-11052
CCL4	-11038
CCL3	-11017
TNFSF14	-10905
FASLG	-10891
CCL5	-10864
IFNL1	-10849
PTPN7	-10824
CCL19	-10801
NANOG	-10800
PRTN3	-10766
CTSG	-10743
CCL2	-10725
HAVCR2	-10654
IL27	-10649
IL13	-10645
STX1A	-10640
EBI3	-10569
CLCF1	-10559
IL1B	-10551

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IFNA7	-11052.0
CCL4	-11038.0
CCL3	-11017.0
TNFSF14	-10905.0
FASLG	-10891.0
CCL5	-10864.0
IFNL1	-10849.0
PTPN7	-10824.0
CCL19	-10801.0
NANOG	-10800.0
PRTN3	-10766.0
CTSG	-10743.0
CCL2	-10725.0
HAVCR2	-10654.0
IL27	-10649.0
IL13	-10645.0
STX1A	-10640.0
EBI3	-10569.0
CLCF1	-10559.0
IL1B	-10551.0
IRF8	-10532.0
IRAK3	-10511.0
HGF	-10497.0
CXCL2	-10475.0
IFI30	-10464.0
CD86	-10367.0
CISH	-10360.0
IL3	-10344.0
IRF1	-10335.0
IL9	-10300.0
SOD2	-10290.0
EIF4E2	-10269.0
IL17RE	-10216.0
IL23R	-10195.0
TNFSF4	-10183.0
BST2	-10179.0
NUP50	-10150.0
TNFRSF6B	-10146.0
TIFA	-10144.0
IFNAR2	-10060.0
UBA3	-10057.0
CXCL10	-9997.0
TNF	-9974.0
IL21	-9969.0
IL18RAP	-9965.0
UBE2M	-9955.0
IFITM1	-9862.0
TRIM45	-9763.0
CXCL1	-9709.0
UBB	-9702.0
SUMO1	-9697.0
ALOX15	-9678.0
PTPN11	-9664.0
MCL1	-9626.0
TNFRSF17	-9609.0
IL6R	-9582.0
IL17A	-9567.0
GBP2	-9552.0
HSPA8	-9533.0
UBA7	-9526.0
OSMR	-9518.0
SH2B3	-9506.0
PTPN12	-9456.0
TNFRSF12A	-9452.0
RHOU	-9450.0
PIK3R2	-9426.0
IL26	-9425.0
CCR5	-9411.0
PSMC4	-9362.0
CCR2	-9318.0
IL1R2	-9287.0
TNFSF13B	-9265.0
TNFRSF9	-9263.0
B2M	-9228.0
NRAS	-9202.0
JAK1	-9200.0
SKP1	-9156.0
IL2	-9114.0
CASP8	-9058.0
TBK1	-9043.0
TNFRSF11A	-9032.0
IL27RA	-8986.0
IL33	-8961.0
NFKBIA	-8939.0
STAT4	-8928.0
S100A12	-8914.0
CTF1	-8911.0
PPM1B	-8864.0
TNFSF12	-8863.0
IL6	-8816.0
IL12A	-8813.0
LIF	-8805.0
PSMA8	-8792.0
CD70	-8737.0
LTBR	-8690.0
HLA-DQA1	-8674.0
RSAD2	-8643.0
EDARADD	-8548.0
SLA2	-8412.0
NOD2	-8386.0
NUP42	-8372.0
SIGIRR	-8358.0
NUP153	-8324.0
TSLP	-8274.0
UBE2V1	-8226.0
EIF4A2	-8210.0
UBE2N	-8206.0
STAT5A	-8197.0
SOX2	-8177.0
PTGS2	-8147.0
AAAS	-8141.0
TNFRSF11B	-8099.0
HNRNPDL	-8005.0
H3C10	-7994.0
UBC	-7974.0
MAPK10	-7890.0
OASL	-7858.0
PSMD12	-7843.0
SHC1	-7816.0
TEC	-7793.0
FOXO1	-7760.0
IL19	-7758.0
MAPK1	-7718.0
ICAM1	-7671.0
TNFRSF1A	-7650.0
IFIT1	-7633.0
ABCE1	-7632.0
ANXA1	-7584.0
SAA1	-7546.0
IL18	-7504.0
GHR	-7469.0
HLA-G	-7464.0
PSMB10	-7431.0
IL2RA	-7427.0
PSMC5	-7419.0
CCL22	-7402.0
NDN	-7380.0
SYK	-7342.0
ELOC	-7318.0
LYN	-7312.0
IL21R	-7309.0
MAP3K8	-7243.0
ARF1	-7239.0
KPNA7	-7191.0
IFNG	-7165.0
IRAK2	-7144.0
LGALS9	-7117.0
IFNAR1	-7114.0
PELI3	-7104.0
PSMB4	-7098.0
OSM	-7026.0
IFIT2	-7019.0
YES1	-6977.0
KPNA5	-6957.0
GSTO1	-6928.0
RPS6KA1	-6926.0
HERC5	-6920.0
EIF4A1	-6854.0
H3C2	-6790.0
PSME4	-6754.0
IL36G	-6688.0
IL1RL1	-6648.0
IL22RA1	-6614.0
IL1R1	-6603.0
RPLP0	-6587.0
YWHAZ	-6541.0
PRLR	-6487.0
UBE2D2	-6483.0
HCK	-6454.0
MAPKAPK3	-6451.0
CRKL	-6411.0
DUSP3	-6269.0
MAPK14	-6253.0
HLA-E	-6243.0
GAB2	-6223.0
IL24	-6219.0
CCND1	-6159.0
NUP35	-6110.0
PSMC2	-6092.0
LTA	-6090.0
PSME2	-6084.0
POM121	-6050.0
HSP90AA1	-6002.0
SOCS2	-6000.0
UBE2E1	-5994.0
PSMA3	-5986.0
LCP1	-5983.0
CAPZA1	-5977.0
TRIM35	-5957.0
KPNA2	-5929.0
GATA3	-5922.0
USP18	-5857.0
PSMB8	-5844.0
PIK3R1	-5752.0
LIFR	-5731.0
KPNB1	-5688.0
HMGB1	-5679.0
LMNB1	-5652.0
BATF	-5590.0
MEF2C	-5570.0
H3C4	-5557.0
FBXW11	-5451.0
NUP205	-5439.0
CANX	-5437.0
IRF5	-5392.0
IL1RAP	-5368.0
MAP3K7	-5328.0
RAE1	-5266.0
IL17RC	-5186.0
CNN2	-5172.0
RALA	-5162.0
TXLNA	-5161.0
H3C12	-5090.0
FYN	-5019.0
TNFSF8	-4863.0
MIF	-4836.0
ELOB	-4810.0
HLA-DRB5	-4803.0
ADAM17	-4731.0
HLA-B	-4701.0
F13A1	-4686.0
PIK3CG	-4685.0
BCL2L11	-4681.0
NUP37	-4666.0
BCL6	-4663.0
VRK3	-4659.0
CCL20	-4657.0
NUP155	-4621.0
SMAD3	-4614.0
RPS6KA5	-4598.0
SP100	-4570.0
TWIST1	-4549.0
UBE2L6	-4548.0
HLA-DPA1	-4518.0
ISG15	-4511.0
PTPN13	-4488.0
NUP133	-4483.0
PSMA5	-4438.0
CUL1	-4436.0
POMC	-4416.0
UBA52	-4361.0
KPNA1	-4347.0
POU2F1	-4327.0
PSMD11	-4325.0
PSMD5	-4244.0
IFNGR1	-4243.0
PPP2CB	-4240.0
NKIRAS2	-4199.0
BIRC3	-4172.0
IP6K2	-4163.0
CASP1	-4103.0
IFIT5	-4096.0
PIM1	-4091.0
HLA-A	-4075.0
IL12B	-4053.0
PSMD9	-3987.0
SAMHD1	-3976.0
TRIM38	-3961.0
PTPN6	-3922.0
LCK	-3915.0
STXBP2	-3888.0
NEDD4	-3882.0
MYC	-3827.0
H3C11	-3817.0
TNIP2	-3790.0
PTPRJ	-3725.0
ALOX5	-3720.0
CXCL8	-3658.0
ZEB1	-3637.0
CIITA	-3612.0
PTPN18	-3557.0
MMP3	-3522.0
BCL2L1	-3491.0
JUNB	-3457.0
FLT3	-3438.0
PSMA6	-3425.0
IL2RB	-3400.0
TNFRSF13C	-3364.0
SOCS3	-3309.0
IRAK4	-3272.0
PTPN1	-3259.0
IFITM3	-3253.0
HIF1A	-3234.0
EIF4G1	-3228.0
RAG2	-3221.0
NFKB1	-3211.0
PIK3R3	-3209.0
IKBIP	-3187.0
RAPGEF1	-3164.0
RBX1	-3122.0
IL17C	-3119.0
APP	-3117.0
MYD88	-3102.0
DUSP6	-3092.0
PLCG2	-3090.0
PSMC1	-3076.0
IFNGR2	-3057.0
PSME3	-3024.0
GRB2	-2984.0
SOD1	-2982.0
PSMB9	-2972.0
TNFSF9	-2962.0
TRIM34	-2894.0
UBE2D3	-2867.0
CDC42	-2824.0
IL22RA2	-2772.0
PELI2	-2762.0
POM121C	-2759.0
SOS2	-2743.0
PTPN2	-2727.0
USP14	-2709.0
KPNA4	-2708.0
PTPN9	-2696.0
MAP2K3	-2693.0
MAPKAPK2	-2623.0
CREB1	-2614.0
INPP5D	-2607.0
GBP5	-2578.0
NFKBIB	-2561.0
IL12RB1	-2560.0
STAT3	-2557.0
NUP43	-2489.0
PPP2CA	-2430.0
IL12RB2	-2412.0
IL10RA	-2397.0
IL15	-2387.0
STAT5B	-2385.0
SNRPA1	-2380.0
IL17RB	-2371.0
HNRNPA2B1	-2347.0
MTAP	-2226.0
IFNLR1	-2217.0
PDE12	-2200.0
TNFSF15	-2180.0
CCL11	-2170.0
HNRNPF	-2138.0
PSMD1	-2120.0
IL7	-2077.0
KPNA3	-2071.0
SLA	-2005.0
S1PR1	-1997.0
BIRC2	-1940.0
NDC1	-1937.0
FPR1	-1811.0
IL6ST	-1796.0
IRF7	-1775.0
HLA-F	-1773.0
PSMB5	-1772.0
EIF2AK2	-1726.0
ARIH1	-1719.0
CD44	-1715.0
PTPRZ1	-1678.0
NOD1	-1677.0
SQSTM1	-1672.0
PSMA1	-1545.0
RPS27A	-1544.0
PIN1	-1506.0
NKIRAS1	-1504.0
MMP9	-1485.0
TAB2	-1440.0
VIM	-1412.0
KRAS	-1382.0
PSMB3	-1361.0
GRAP2	-1305.0
MAP3K3	-1296.0
OAS3	-1196.0
LTB	-1174.0
TP53	-1167.0
RAP1B	-1070.0
RORA	-1030.0
GRB10	-889.0
BRWD1	-847.0
TRIM25	-816.0
CSK	-783.0
CFL1	-741.0
PIK3CA	-717.0
CASP3	-699.0
GBP1	-684.0
SOCS6	-660.0
PSME1	-658.0
CRLF1	-613.0
RNF7	-582.0
IFNA6	-577.0
CD36	-543.0
DUSP4	-512.0
PTK2B	-464.0
VAV1	-400.0
FCER2	-366.0
STAT1	-317.0
DUSP7	-261.0
TRAF6	-191.0
ITGB1	-101.0
HLA-DRA	-78.0
IRF2	-77.0
ATF2	-41.0
MAPK7	-30.0
SEM1	-1.0
IRF3	23.0
NUP85	69.0
NUP214	74.0
CAMK2D	77.0
NFKB2	109.0
EGR1	131.0
HLA-DQB1	146.0
HSP90B1	178.0
JAK3	218.0
PSMD8	315.0
IL1RL2	350.0
MAP2K1	378.0
HLA-H	394.0
PIAS1	398.0
JUN	408.0
CSF3	554.0
CBL	556.0
TRIM46	564.0
CDKN1A	606.0
GBP4	614.0
PRKCD	639.0
CSF1R	671.0
BTRC	810.0
IRS1	893.0
PSMA7	942.0
TRIM3	986.0
CD27	989.0
ITGAM	1055.0
PSMA2	1059.0
HSPA9	1078.0
MAP2K6	1098.0
PSMD7	1158.0
TRIM14	1185.0
HLA-DQA2	1187.0
PPP2R1A	1222.0
CUL5	1236.0
SH2B1	1240.0
IL1A	1307.0
MX1	1420.0
TRIM22	1475.0
IL11	1528.0
NUP107	1548.0
PSMB2	1566.0
TNFSF13	1598.0
TALDO1	1601.0
IL5	1605.0
HLA-C	1645.0
TRIM31	1672.0
IL16	1727.0
BLNK	1792.0
EIF4G3	1829.0
IL1RN	1911.0
GSDMD	1972.0
MAP3K14	2022.0
CDKN1B	2040.0
SEH1L	2049.0
BCL2	2097.0
EIF4G2	2111.0
IL15RA	2137.0
PIK3CD	2150.0
COL1A2	2152.0
CAMK2G	2220.0
TNFRSF18	2234.0
MMP2	2239.0
STX3	2273.0
SMAD7	2299.0
PSMD14	2369.0
TRAF2	2552.0
TRIM21	2664.0
ATF1	2712.0
PELI1	2717.0
N4BP1	2722.0
TNFRSF25	2736.0
NUP88	2756.0
PSMC3	2777.0
ITGB2	2817.0
NUP188	2838.0
CRK	2872.0
NUP160	2878.0
TNFRSF1B	2930.0
MAPK11	2972.0
IL36B	2975.0
OPRM1	3059.0
PDCD4	3066.0
PTAFR	3097.0
FOXO3	3101.0
MMP1	3150.0
CNTF	3179.0
GBP7	3197.0
IL36A	3203.0
STX4	3204.0
EIF4E	3258.0
RIGI	3277.0
FN1	3290.0
PSMD13	3304.0
MAPK8	3348.0
RELB	3360.0
SOS1	3385.0
TRIM2	3399.0
ABL2	3439.0
IL10	3533.0
TPR	3550.0
PSMB7	3558.0
HLA-DRB1	3572.0
THOC5	3615.0
MUC1	3626.0
PSMD4	3642.0
IL20RA	3695.0
PSMD2	3699.0
IFNA14	3716.0
AIP	3728.0
CNTFR	3739.0
TGFB1	3769.0
PTPN23	3802.0
EIF4E3	3812.0
AKT3	3841.0
IFI35	3864.0
NUP98	3900.0
ITGAX	3938.0
NOS2	3966.0
OAS1	3981.0
MX2	4026.0
TRAF3	4031.0
TNFRSF8	4034.0
PSMA4	4073.0
CSF2	4089.0
CD40	4116.0
TRIM17	4123.0
PRL	4176.0
H3C1	4262.0
SOCS1	4311.0
PRKACA	4352.0
VCAM1	4365.0
IKBKB	4370.0
PSMC6	4442.0
IL18R1	4451.0
PSMD6	4479.0
MEF2A	4487.0
PTPN14	4491.0
FSCN1	4492.0
RPS6KA2	4563.0
RAG1	4572.0
CCR1	4588.0
RIPK2	4589.0
IL31RA	4619.0
IL17F	4641.0
UBE2D1	4660.0
GBP3	4679.0
CAMK2A	4700.0
MAPK9	4786.0
FLNB	4794.0
IRS2	4801.0
FLT3LG	4867.0
SDC1	4882.0
PITPNA	4905.0
FOS	4918.0
IL10RB	4940.0
NUP54	4974.0
RORC	5052.0
TRIM8	5109.0
PPIA	5114.0
PSMB6	5196.0
PSMF1	5201.0
LRRC14	5202.0
TRIM26	5272.0
PPP2R5D	5283.0
H3C7	5307.5
OAS2	5349.0
CSF1	5409.0
PSMB1	5414.0
MT2A	5459.0
NUP93	5467.0
FGF2	5483.0
IRF9	5526.0
PAK2	5575.0
IRF4	5580.0
ISG20	5599.0
CEBPD	5604.0
IFNA2	5611.0
SNAP25	5636.0
TRIM10	5646.0
IFNA21	5650.0
IL7R	5673.0
EIF4A3	5714.0
NUP210	5745.0
SOCS5	5765.0
TRIM6	5832.0
CA1	5845.0
NUP58	5846.0
VEGFA	5881.0
ANXA2	5910.0
OPRD1	6077.0
CD80	6145.0
HLA-DQB2	6178.0
MAPK3	6201.0
HLA-DPB1	6276.0
TCP1	6326.0
NLRX1	6433.0
BIRC5	6513.0
ADAR	6532.0
EDAR	6535.0
HMOX1	6570.0
IRF6	6571.0
H3C6	6602.0
IFNB1	6637.0
IFIT3	6685.0
IL22	6688.0
IFNA13	6710.0
PML	6714.0
IL25	6733.0
TYK2	6837.0
STAT6	6841.0
IL20RB	6880.0
PIK3CB	6910.0
ALPK1	6923.0
IFNA5	6924.0
TNFRSF13B	6944.0
IFI6	6947.0
IL17RA	6980.0
MAP2K4	6996.0
IL37	7007.0
JAK2	7130.0
TRIM5	7232.0
IFNA8	7263.0
NCAM1	7268.0
TNFSF11	7356.0
RANBP2	7396.0
CHUK	7456.0
NUP62	7457.0
XAF1	7523.0
PTPN4	7596.0
CD4	7638.0
RELA	7644.0
TOLLIP	7660.0
TNFSF18	7675.0
S100B	7729.0
TRIM68	7790.0
VAMP2	7819.0
AKT1	7830.0
LBP	7851.0
IL5RA	7931.0
IL1F10	8014.0
IFNA1	8075.0
NLRC5	8083.0
PSMD3	8120.0
IL11RA	8161.0
IL4	8170.0
STAT2	8216.0
TAB1	8248.0
AGER	8360.0
CAMK2B	8374.0
MAP2K7	8419.0
RNASEL	8429.0
IL34	8441.0
HRAS	8450.0
SEC13	8482.0
TRIM62	8537.0
IL23A	8542.0
INPPL1	8693.0
SRC	8731.0
IL20	8765.0
PPP2R1B	8914.0
SERPINB2	8983.0
IFITM2	9007.0
PLCG1	9033.0
PTPN5	9036.0
CSF3R	9112.0
TNFRSF4	9118.0
H3C3	9119.0
IL31	9223.0
IL4R	9245.0
SMARCA4	9287.0
GBP6	9587.0
AKT2	9642.0
IL36RN	9745.0
PSMB11	9803.0
LCN2	9859.0
H3C8	9880.0
TRIM29	9938.0
CSF2RB	9948.0
IL32	10084.0
IFNA16	10109.0
LAMA5	10157.0
IL18BP	10172.0
GSTA2	10194.0
P4HB	10390.0
GH2	10424.0
IFI27	10502.0
GH1	10669.0
CSH1	10696.0
IFNL2	10834.0

---

REACTOME_SIGNALING_BY_INTERLEUKINS

REACTOME_SIGNALING_BY_INTERLEUKINS

	800
set	REACTOME_SIGNALING_BY_INTERLEUKINS
setSize	444
pANOVA	1.36e-06
s.dist	-0.134
p.adjustANOVA	0.000223

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CCL4	-11038
CCL3	-11017
FASLG	-10891
CCL5	-10864
IFNL1	-10849
PTPN7	-10824
CCL19	-10801
NANOG	-10800
PRTN3	-10766
CTSG	-10743
CCL2	-10725
HAVCR2	-10654
IL27	-10649
IL13	-10645
STX1A	-10640
EBI3	-10569
CLCF1	-10559
IL1B	-10551
IRAK3	-10511
HGF	-10497

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CCL4	-11038.0
CCL3	-11017.0
FASLG	-10891.0
CCL5	-10864.0
IFNL1	-10849.0
PTPN7	-10824.0
CCL19	-10801.0
NANOG	-10800.0
PRTN3	-10766.0
CTSG	-10743.0
CCL2	-10725.0
HAVCR2	-10654.0
IL27	-10649.0
IL13	-10645.0
STX1A	-10640.0
EBI3	-10569.0
CLCF1	-10559.0
IL1B	-10551.0
IRAK3	-10511.0
HGF	-10497.0
CXCL2	-10475.0
CD86	-10367.0
CISH	-10360.0
IL3	-10344.0
IL9	-10300.0
SOD2	-10290.0
IL17RE	-10216.0
IL23R	-10195.0
TIFA	-10144.0
CXCL10	-9997.0
TNF	-9974.0
IL21	-9969.0
IL18RAP	-9965.0
CXCL1	-9709.0
UBB	-9702.0
ALOX15	-9678.0
PTPN11	-9664.0
MCL1	-9626.0
IL6R	-9582.0
IL17A	-9567.0
HSPA8	-9533.0
OSMR	-9518.0
PTPN12	-9456.0
RHOU	-9450.0
PIK3R2	-9426.0
IL26	-9425.0
CCR5	-9411.0
PSMC4	-9362.0
CCR2	-9318.0
IL1R2	-9287.0
JAK1	-9200.0
SKP1	-9156.0
IL2	-9114.0
CASP8	-9058.0
TBK1	-9043.0
IL27RA	-8986.0
IL33	-8961.0
NFKBIA	-8939.0
STAT4	-8928.0
S100A12	-8914.0
CTF1	-8911.0
IL6	-8816.0
IL12A	-8813.0
LIF	-8805.0
PSMA8	-8792.0
NOD2	-8386.0
SIGIRR	-8358.0
TSLP	-8274.0
UBE2V1	-8226.0
UBE2N	-8206.0
STAT5A	-8197.0
SOX2	-8177.0
PTGS2	-8147.0
HNRNPDL	-8005.0
H3C10	-7994.0
UBC	-7974.0
MAPK10	-7890.0
PSMD12	-7843.0
SHC1	-7816.0
TEC	-7793.0
FOXO1	-7760.0
IL19	-7758.0
MAPK1	-7718.0
ICAM1	-7671.0
TNFRSF1A	-7650.0
ANXA1	-7584.0
SAA1	-7546.0
IL18	-7504.0
PSMB10	-7431.0
IL2RA	-7427.0
PSMC5	-7419.0
CCL22	-7402.0
NDN	-7380.0
SYK	-7342.0
LYN	-7312.0
IL21R	-7309.0
MAP3K8	-7243.0
ARF1	-7239.0
IFNG	-7165.0
IRAK2	-7144.0
LGALS9	-7117.0
PELI3	-7104.0
PSMB4	-7098.0
OSM	-7026.0
YES1	-6977.0
GSTO1	-6928.0
RPS6KA1	-6926.0
H3C2	-6790.0
PSME4	-6754.0
IL36G	-6688.0
IL1RL1	-6648.0
IL22RA1	-6614.0
IL1R1	-6603.0
RPLP0	-6587.0
YWHAZ	-6541.0
HCK	-6454.0
MAPKAPK3	-6451.0
CRKL	-6411.0
DUSP3	-6269.0
MAPK14	-6253.0
GAB2	-6223.0
IL24	-6219.0
CCND1	-6159.0
PSMC2	-6092.0
PSME2	-6084.0
HSP90AA1	-6002.0
SOCS2	-6000.0
PSMA3	-5986.0
LCP1	-5983.0
CAPZA1	-5977.0
GATA3	-5922.0
USP18	-5857.0
PSMB8	-5844.0
PIK3R1	-5752.0
LIFR	-5731.0
HMGB1	-5679.0
LMNB1	-5652.0
BATF	-5590.0
MEF2C	-5570.0
H3C4	-5557.0
FBXW11	-5451.0
CANX	-5437.0
IL1RAP	-5368.0
MAP3K7	-5328.0
IL17RC	-5186.0
CNN2	-5172.0
RALA	-5162.0
TXLNA	-5161.0
H3C12	-5090.0
FYN	-5019.0
MIF	-4836.0
F13A1	-4686.0
BCL6	-4663.0
VRK3	-4659.0
CCL20	-4657.0
SMAD3	-4614.0
RPS6KA5	-4598.0
TWIST1	-4549.0
PTPN13	-4488.0
PSMA5	-4438.0
CUL1	-4436.0
POMC	-4416.0
UBA52	-4361.0
POU2F1	-4327.0
PSMD11	-4325.0
PSMD5	-4244.0
PPP2CB	-4240.0
NKIRAS2	-4199.0
CASP1	-4103.0
PIM1	-4091.0
IL12B	-4053.0
PSMD9	-3987.0
PTPN6	-3922.0
LCK	-3915.0
STXBP2	-3888.0
MYC	-3827.0
H3C11	-3817.0
TNIP2	-3790.0
ALOX5	-3720.0
CXCL8	-3658.0
ZEB1	-3637.0
PTPN18	-3557.0
MMP3	-3522.0
BCL2L1	-3491.0
JUNB	-3457.0
PSMA6	-3425.0
IL2RB	-3400.0
SOCS3	-3309.0
IRAK4	-3272.0
HIF1A	-3234.0
RAG2	-3221.0
NFKB1	-3211.0
PIK3R3	-3209.0
IKBIP	-3187.0
RAPGEF1	-3164.0
RBX1	-3122.0
IL17C	-3119.0
APP	-3117.0
MYD88	-3102.0
DUSP6	-3092.0
PSMC1	-3076.0
PSME3	-3024.0
GRB2	-2984.0
SOD1	-2982.0
PSMB9	-2972.0
CDC42	-2824.0
IL22RA2	-2772.0
PELI2	-2762.0
SOS2	-2743.0
PTPN2	-2727.0
USP14	-2709.0
PTPN9	-2696.0
MAP2K3	-2693.0
MAPKAPK2	-2623.0
CREB1	-2614.0
INPP5D	-2607.0
NFKBIB	-2561.0
IL12RB1	-2560.0
STAT3	-2557.0
PPP2CA	-2430.0
IL12RB2	-2412.0
IL10RA	-2397.0
IL15	-2387.0
STAT5B	-2385.0
SNRPA1	-2380.0
IL17RB	-2371.0
HNRNPA2B1	-2347.0
MTAP	-2226.0
IFNLR1	-2217.0
CCL11	-2170.0
HNRNPF	-2138.0
PSMD1	-2120.0
IL7	-2077.0
S1PR1	-1997.0
FPR1	-1811.0
IL6ST	-1796.0
PSMB5	-1772.0
PTPRZ1	-1678.0
NOD1	-1677.0
SQSTM1	-1672.0
PSMA1	-1545.0
RPS27A	-1544.0
NKIRAS1	-1504.0
MMP9	-1485.0
TAB2	-1440.0
VIM	-1412.0
PSMB3	-1361.0
MAP3K3	-1296.0
TP53	-1167.0
RAP1B	-1070.0
RORA	-1030.0
BRWD1	-847.0
CFL1	-741.0
PIK3CA	-717.0
CASP3	-699.0
PSME1	-658.0
CRLF1	-613.0
CD36	-543.0
DUSP4	-512.0
PTK2B	-464.0
VAV1	-400.0
FCER2	-366.0
STAT1	-317.0
DUSP7	-261.0
TRAF6	-191.0
ITGB1	-101.0
ATF2	-41.0
MAPK7	-30.0
SEM1	-1.0
NFKB2	109.0
HSP90B1	178.0
JAK3	218.0
PSMD8	315.0
IL1RL2	350.0
MAP2K1	378.0
JUN	408.0
CSF3	554.0
CBL	556.0
CDKN1A	606.0
CSF1R	671.0
BTRC	810.0
IRS1	893.0
PSMA7	942.0
ITGAM	1055.0
PSMA2	1059.0
HSPA9	1078.0
MAP2K6	1098.0
PSMD7	1158.0
PPP2R1A	1222.0
IL1A	1307.0
IL11	1528.0
PSMB2	1566.0
TALDO1	1601.0
IL5	1605.0
IL16	1727.0
BLNK	1792.0
IL1RN	1911.0
GSDMD	1972.0
BCL2	2097.0
IL15RA	2137.0
PIK3CD	2150.0
COL1A2	2152.0
MMP2	2239.0
STX3	2273.0
PSMD14	2369.0
TRAF2	2552.0
ATF1	2712.0
PELI1	2717.0
N4BP1	2722.0
PSMC3	2777.0
ITGB2	2817.0
CRK	2872.0
TNFRSF1B	2930.0
MAPK11	2972.0
IL36B	2975.0
OPRM1	3059.0
PDCD4	3066.0
PTAFR	3097.0
FOXO3	3101.0
MMP1	3150.0
CNTF	3179.0
IL36A	3203.0
STX4	3204.0
FN1	3290.0
PSMD13	3304.0
MAPK8	3348.0
SOS1	3385.0
IL10	3533.0
PSMB7	3558.0
MUC1	3626.0
PSMD4	3642.0
IL20RA	3695.0
PSMD2	3699.0
AIP	3728.0
CNTFR	3739.0
TGFB1	3769.0
PTPN23	3802.0
ITGAX	3938.0
NOS2	3966.0
PSMA4	4073.0
CSF2	4089.0
H3C1	4262.0
SOCS1	4311.0
PRKACA	4352.0
VCAM1	4365.0
IKBKB	4370.0
PSMC6	4442.0
IL18R1	4451.0
PSMD6	4479.0
MEF2A	4487.0
PTPN14	4491.0
FSCN1	4492.0
RPS6KA2	4563.0
RAG1	4572.0
CCR1	4588.0
RIPK2	4589.0
IL31RA	4619.0
IL17F	4641.0
MAPK9	4786.0
IRS2	4801.0
SDC1	4882.0
PITPNA	4905.0
FOS	4918.0
IL10RB	4940.0
RORC	5052.0
PPIA	5114.0
PSMB6	5196.0
PSMF1	5201.0
LRRC14	5202.0
PPP2R5D	5283.0
H3C7	5307.5
CSF1	5409.0
PSMB1	5414.0
FGF2	5483.0
PAK2	5575.0
IRF4	5580.0
CEBPD	5604.0
SNAP25	5636.0
IL7R	5673.0
SOCS5	5765.0
CA1	5845.0
VEGFA	5881.0
ANXA2	5910.0
OPRD1	6077.0
CD80	6145.0
MAPK3	6201.0
TCP1	6326.0
NLRX1	6433.0
BIRC5	6513.0
HMOX1	6570.0
H3C6	6602.0
IL22	6688.0
IL25	6733.0
TYK2	6837.0
STAT6	6841.0
IL20RB	6880.0
PIK3CB	6910.0
ALPK1	6923.0
IL17RA	6980.0
MAP2K4	6996.0
IL37	7007.0
JAK2	7130.0
CHUK	7456.0
PTPN4	7596.0
CD4	7638.0
RELA	7644.0
TOLLIP	7660.0
S100B	7729.0
VAMP2	7819.0
AKT1	7830.0
LBP	7851.0
IL5RA	7931.0
IL1F10	8014.0
NLRC5	8083.0
PSMD3	8120.0
IL11RA	8161.0
IL4	8170.0
STAT2	8216.0
TAB1	8248.0
AGER	8360.0
MAP2K7	8419.0
IL34	8441.0
IL23A	8542.0
INPPL1	8693.0
IL20	8765.0
PPP2R1B	8914.0
SERPINB2	8983.0
PTPN5	9036.0
CSF3R	9112.0
H3C3	9119.0
IL31	9223.0
IL4R	9245.0
SMARCA4	9287.0
IL36RN	9745.0
PSMB11	9803.0
LCN2	9859.0
H3C8	9880.0
CSF2RB	9948.0
IL32	10084.0
LAMA5	10157.0
IL18BP	10172.0
GSTA2	10194.0
P4HB	10390.0
IFNL2	10834.0

---

REACTOME_TRANSLATION

REACTOME_TRANSLATION

	1152
set	REACTOME_TRANSLATION
setSize	278
pANOVA	1.91e-06
s.dist	-0.166
p.adjustANOVA	0.000285

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL29	-10734
RPS12	-10480
MRPL45	-10457
CHCHD1	-10178
EEF1G	-10100
RPS25	-9996
RPL12	-9789
MRPS18A	-9661
RPL23	-9573
RPL18	-9396
PPA1	-9356
RPL10L	-9192
MRPL41	-9181
SPCS1	-9174
RPL13	-9165
SRP72	-9160
EIF3J	-9090
RPL10A	-8981
MRPS23	-8957
SEC61B	-8931

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL29	-10734.0
RPS12	-10480.0
MRPL45	-10457.0
CHCHD1	-10178.0
EEF1G	-10100.0
RPS25	-9996.0
RPL12	-9789.0
MRPS18A	-9661.0
RPL23	-9573.0
RPL18	-9396.0
PPA1	-9356.0
RPL10L	-9192.0
MRPL41	-9181.0
SPCS1	-9174.0
RPL13	-9165.0
SRP72	-9160.0
EIF3J	-9090.0
RPL10A	-8981.0
MRPS23	-8957.0
SEC61B	-8931.0
RPS13	-8885.0
MRPS18C	-8882.0
RPL24	-8697.0
MARS2	-8687.0
RPS26	-8630.0
RPS6	-8578.0
RPL41	-8474.0
MRPS16	-8448.0
MRPL37	-8369.0
HARS2	-8314.0
ETF1	-8311.0
RPS28	-8280.0
RPL13A	-8267.5
EIF4A2	-8210.0
RPL14	-8156.0
RPL11	-8150.0
MRPL30	-8122.0
MRPL11	-8067.0
RPL4	-8026.0
RPL7	-8006.0
MTRF1L	-7950.0
RPL39L	-7836.0
EIF2S1	-7708.0
FAU	-7687.0
MRPL58	-7637.0
HARS1	-7476.0
RPL34	-7413.0
MRPL14	-7333.0
RPS15A	-7332.0
EIF3F	-7308.0
LARS1	-7222.0
MRPL33	-7210.0
EIF4H	-7179.0
RPL5	-7169.0
MRPS9	-6975.0
RPSA	-6914.0
EIF4A1	-6854.0
RPL36AL	-6833.5
SRPRA	-6789.0
ERAL1	-6773.0
RPL37	-6752.0
RPN1	-6622.0
MRPL12	-6605.0
RPLP0	-6587.0
EIF2S2	-6580.0
RPL23A	-6481.0
RPL35A	-6473.0
MTIF2	-6461.0
EIF2B2	-6405.0
RPL21	-6325.0
EEF1B2	-6321.0
EIF5B	-6305.0
RPL22L1	-6284.0
MRPS18B	-6206.0
RPS3A	-6158.0
MRPS34	-6153.0
MRPL49	-6081.0
MRPS24	-6052.0
MRPS33	-6051.0
RPL17	-5981.0
MRPS15	-5968.0
SSR2	-5934.0
MRPS2	-5896.0
YARS2	-5804.0
RPL27A	-5715.0
RPS24	-5677.0
RPL18A	-5525.0
MRPL42	-5462.0
EIF3D	-5426.0
RPS18	-5357.0
EIF2B3	-5284.0
RPL35	-5265.0
MRPS26	-5245.0
SPCS2	-5141.0
RPL8	-5017.0
SRP14	-4955.0
MRPL20	-4869.0
RPS20	-4837.0
SRP9	-4687.0
YARS1	-4677.0
RPLP2	-4592.0
MRPL13	-4496.0
GSPT1	-4445.0
SEC11A	-4435.0
EEF1A1	-4419.0
SRP19	-4414.0
UBA52	-4361.0
NARS1	-4355.0
GFM2	-4315.0
RPL28	-4300.0
RPS10	-4220.0
RPS11	-4189.0
PPA2	-4167.0
EIF2B1	-3939.0
RPS5	-3903.0
RPL36	-3867.0
SRP54	-3691.0
MRPL57	-3536.0
RPLP1	-3490.0
RPL15	-3478.0
MRPL51	-3394.0
RARS1	-3393.0
TRMT112	-3360.0
EPRS1	-3352.0
EIF2B4	-3323.0
RPS29	-3289.0
EIF4G1	-3228.0
MRPL35	-3225.0
MTIF3	-3199.0
RPL19	-3065.0
SEC11C	-2799.0
RPL9	-2640.0
MRPL54	-2629.0
RPS16	-2594.0
GADD45GIP1	-2521.0
RPL30	-2386.0
RPS15	-2337.0
FARSB	-2329.0
EIF3H	-2264.0
RPL6	-2141.0
MTFMT	-2033.0
RPL3	-1846.0
N6AMT1	-1793.0
MRPS21	-1742.0
RPS2	-1664.0
GFM1	-1605.0
RPS27A	-1544.0
WARS1	-1474.0
TSFM	-1359.0
RPL38	-1357.0
RPS8	-1326.0
MRPL52	-1312.0
AIMP1	-1209.0
RPS23	-1205.0
EEF1E1	-1139.0
MRPL3	-1132.0
PARS2	-1122.0
MARS1	-1103.0
RPL37A	-1087.0
MRPL55	-1050.0
MRPL17	-938.0
EIF3K	-868.0
RPS21	-811.0
OXA1L	-786.0
MRPL48	-748.0
TRAM1	-734.0
EIF4B	-617.0
PABPC1	-486.0
WARS2	-485.0
GARS1	-477.0
MRPL53	-433.0
MRPL27	-340.0
NARS2	-245.0
VARS1	-166.0
EIF4EBP1	-165.0
SPCS3	-152.0
MRPS7	-124.0
RPS9	-121.0
EIF5	-46.0
MRPS31	49.0
RPL32	63.0
SRPRB	213.0
MRPS11	228.0
MRPS27	296.0
MRPS28	313.0
EIF3I	364.0
SEC61A1	385.0
KARS1	432.0
MRPS12	607.0
EEF1A2	729.0
SARS2	831.0
DARS1	860.0
MRPS30	878.0
MRPL1	889.0
EIF3L	931.0
MRPL40	1041.0
RARS2	1050.0
MRPL47	1119.0
MRPL15	1301.0
MRPL50	1377.0
DARS2	1462.0
PTCD3	1607.0
MRPL36	1689.0
RPN2	1748.0
MRPL4	1750.0
EIF3G	1836.0
MRPL16	1838.0
MRPS10	1843.0
RPS7	1873.0
MRRF	2043.0
MRPL10	2084.0
DAP3	2455.0
AIMP2	2477.0
MRPL2	2556.0
EIF3M	2569.0
MRPS35	2612.0
IARS1	2625.0
MRPL32	2875.0
FARS2	3031.0
MRPL9	3078.0
MRPL43	3080.0
EIF4E	3258.0
RPL26L1	3302.0
RPL27	3305.0
SEC61G	3332.0
MRPL22	3397.0
MRPL44	3414.0
SSR3	3513.0
EARS2	3574.0
MRPS22	3666.0
MRPL24	3684.0
TARS2	3700.0
RPL26	3766.0
TUFM	3781.0
SRP68	3852.0
IARS2	3866.0
RPS27L	3876.0
MRPS5	3917.0
FARSA	4226.0
MRPL39	4287.0
RPL7A	4313.0
SSR1	4480.0
LARS2	4608.0
MRPS25	4722.0
TARS1	4758.0
MRPL19	4881.0
MRPS6	5665.0
MRPL46	5737.0
EEF2	5833.0
MRPS14	5900.0
MRPS17	6295.0
MRPL21	6405.0
VARS2	6675.0
EIF3A	6716.0
MRPL34	6725.0
MRPL18	6968.0
RPL31	7031.0
RPS3	7084.0
EIF2B5	7100.0
AURKAIP1	7327.0
CARS2	7429.0
RPS27	7437.0
DDOST	7512.0
RPL22	7534.0
MRPL23	7595.0
RPS14	7712.0
RPS19	7721.0
AARS2	8079.0
AARS1	8130.0
EIF3E	8167.0
SEC61A2	8187.0
MRPL28	8474.0
EIF3B	8505.0
EEF1D	9215.0
CARS1	9358.0
RPL3L	9685.0
MRPL38	9816.0
APEH	9887.0

---

REACTOME_INTERLEUKIN_10_SIGNALING

REACTOME_INTERLEUKIN_10_SIGNALING

	1039
set	REACTOME_INTERLEUKIN_10_SIGNALING
setSize	43
pANOVA	2.42e-06
s.dist	-0.415
p.adjustANOVA	0.00033

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CCL4	-11038
CCL3	-11017
CCL5	-10864
CCL19	-10801
CCL2	-10725
IL1B	-10551
CXCL2	-10475
CD86	-10367
CXCL10	-9997
TNF	-9974
CXCL1	-9709
CCR5	-9411
CCR2	-9318
IL1R2	-9287
JAK1	-9200
IL6	-8816
IL12A	-8813
LIF	-8805
PTGS2	-8147
ICAM1	-7671

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CCL4	-11038
CCL3	-11017
CCL5	-10864
CCL19	-10801
CCL2	-10725
IL1B	-10551
CXCL2	-10475
CD86	-10367
CXCL10	-9997
TNF	-9974
CXCL1	-9709
CCR5	-9411
CCR2	-9318
IL1R2	-9287
JAK1	-9200
IL6	-8816
IL12A	-8813
LIF	-8805
PTGS2	-8147
ICAM1	-7671
TNFRSF1A	-7650
IL18	-7504
CCL22	-7402
IL1R1	-6603
CCL20	-4657
IL12B	-4053
CXCL8	-3658
STAT3	-2557
IL10RA	-2397
FPR1	-1811
FCER2	-366
CSF3	554
IL1A	1307
IL1RN	1911
TNFRSF1B	2930
PTAFR	3097
IL10	3533
CSF2	4089
CCR1	4588
IL10RB	4940
CSF1	5409
CD80	6145
TYK2	6837

---

REACTOME_SENSORY_PERCEPTION

REACTOME_SENSORY_PERCEPTION

	1581
set	REACTOME_SENSORY_PERCEPTION
setSize	555
pANOVA	6.41e-06
s.dist	0.112
p.adjustANOVA	0.00081

Top enriched genes

Top 20 genes

GeneID	Gene Rank
OR7E24	10876
OR5H1	10861
OR2S2	10775
OR3A1	10767
GNB3	10726
OR56B1	10698
TAS2R31	10686
CLPS	10683
PDE6G	10662
OR6K6	10631
OR2K2	10599
CIB2	10562
CHRNA10	10508
OR1K1	10503
OR1J1	10471
OR2AP1	10468
APOA4	10460
OR2T1	10425
CALHM3	10310
OR2AE1	10309

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
OR7E24	10876.0
OR5H1	10861.0
OR2S2	10775.0
OR3A1	10767.0
GNB3	10726.0
OR56B1	10698.0
TAS2R31	10686.0
CLPS	10683.0
PDE6G	10662.0
OR6K6	10631.0
OR2K2	10599.0
CIB2	10562.0
CHRNA10	10508.0
OR1K1	10503.0
OR1J1	10471.0
OR2AP1	10468.0
APOA4	10460.0
OR2T1	10425.0
CALHM3	10310.0
OR2AE1	10309.0
OR3A3	10275.0
OR52W1	10263.0
TAS1R3	10248.0
OR5K1	10247.0
OR9A4	10214.0
RLBP1	10213.0
AKR1C1	10187.0
OR51D1	10170.0
OR52N2	10150.0
OR2D3	10143.0
AKR1B10	10077.0
CABP2	10061.0
GNGT1	10046.0
OR2B11	10009.0
OR5T2	9973.0
OR5H6	9947.0
OR52E8	9927.0
GUCA1A	9914.0
OR7A5	9895.0
GPIHBP1	9877.0
PDE6B	9851.0
OR52J3	9704.0
OR2V2	9687.0
OR4D10	9665.0
OR4X2	9661.0
OR2A2	9627.0
OR4N2	9590.0
OR4D1	9580.0
CNGA4	9570.0
ADCY3	9563.0
TAS2R10	9550.0
OR4D5	9526.0
OR6C1	9507.0
OR52L1	9501.0
OR5B2	9482.0
OR2M4	9461.0
OR11L1	9441.0
OR5M3	9421.0
TAS2R30	9389.0
OR10A2	9379.0
TAS2R41	9370.0
OR6V1	9304.0
OR7G2	9286.0
SDC4	9285.0
OR1I1	9251.0
OR1D2	9226.0
ATP2B1	9222.0
TAS2R50	9219.0
OR6C75	9169.0
OR52I2	9151.0
OR10K1	9135.0
OR2M2	9134.0
OR10A3	9125.0
OR5C1	9115.0
OR1M1	9108.0
OR5H2	9080.0
RHO	9068.0
APOA2	9060.0
RTP2	9032.0
OR2D2	8987.0
MYO15A	8971.0
OR2A12	8932.0
OR5B12	8931.0
OR2Y1	8918.0
OR2V1	8877.0
OR8I2	8842.0
OR5W2	8829.0
OR6B1	8817.0
CALHM1	8790.0
OR2G2	8761.0
OR2B3	8707.0
LRP1	8698.0
OR4E2	8675.0
GUCA1B	8669.0
GPC1	8651.0
CACNA2D2	8589.0
LRP10	8587.0
LRP8	8544.0
OR13J1	8519.0
OTOF	8461.0
OR13C3	8426.0
OR2F1	8401.0
GRK7	8355.0
OR1E1	8350.0
OR4D9	8348.0
TAS2R39	8334.0
SAG	8311.0
SDR9C7	8267.0
OR7D4	8260.0
APOE	8250.0
OR13C4	8233.0
TWF2	8209.0
SPTAN1	8195.0
OR13C9	8188.0
ITPR3	8146.0
OR10C1	8126.0
OR8U1	8095.0
OR5K3	8090.0
OR1A2	8086.0
TAS2R46	8037.0
OR51E2	8012.0
OR5H15	7927.0
TAS2R14	7913.0
RPE65	7891.0
OR10Q1	7885.0
ATP2B2	7828.0
OR2G3	7826.0
MYO7A	7822.0
VAMP2	7819.0
OR8D1	7696.0
TAS1R2	7606.0
CTBP2	7591.0
OR11G2	7578.0
OR6C65	7547.0
OR6Y1	7504.0
CDH23	7463.0
OR10AD1	7462.0
OR7D2	7459.0
OPN1SW	7455.0
OR10Z1	7424.0
OR51I2	7414.0
AKR1C3	7395.0
MYO1C	7342.0
OR5AC2	7286.0
OR13C2	7278.0
OR5D18	7246.0
STRA6	7217.0
OR5K4	7123.0
OR5AR1	7073.0
GNAT3	7017.0
OR10A7	7002.0
TAS2R20	6994.0
OR2L3	6959.0
OR3A2	6958.0
OR5D13	6956.0
OR2Z1	6881.0
OR2W3	6873.0
OR8J3	6819.0
OR2T27	6613.0
APOM	6588.0
PLB1	6566.0
DNAJC5	6554.0
TAS2R5	6518.0
USH1C	6498.0
GPC2	6489.0
TAS1R1	6430.0
OR4K2	6422.0
OR2AG2	6337.0
KCNQ4	6334.0
OR52R1	6281.0
OR4B1	6263.0
OR2AK2	6181.0
OR2J2	6100.0
OR4L1	6098.0
RBP3	6091.0
OR5V1	6052.0
OR2C3	6035.0
HSPG2	6016.0
OR8B8	6012.0
OR10H4	5888.0
OR4D2	5859.0
OR52D1	5838.0
OR5F1	5782.0
APOC3	5769.0
STRC	5728.0
GUCY2D	5655.0
CNGA1	5645.0
SNAP25	5636.0
MYH9	5470.0
SCNN1B	5469.0
OR8U3	5430.0
OR6X1	5348.0
DHRS3	5341.0
OR52N1	5338.0
OR8B2	5309.0
EPB41L1	5254.0
TRPM5	5250.0
OR6S1	5190.0
PLCB2	5178.0
OR11H4	5120.0
BSN	5075.0
APOA1	5027.0
OR52H1	5017.0
NAPEPLD	5011.0
OR51M1	4937.0
OR1G1	4898.0
SDC1	4882.0
OR11A1	4862.0
OR2B2	4833.0
GRM4	4800.0
FSCN2	4790.0
RDH16	4784.0
RDH11	4714.0
OR6B3	4629.0
OR2C1	4598.0
SCNN1A	4568.0
OR10X1	4518.0
OR5K2	4515.0
OR13F1	4514.0
CNGB1	4460.0
GUCA1C	4424.0
TAS2R7	4191.0
TMC2	4162.0
OR6C2	4045.0
OR4K1	3971.0
TTR	3955.0
OR14A16	3953.0
OR2A14	3924.0
GSN	3907.0
OR4C15	3880.0
CLIC5	3867.0
OR1N1	3818.0
OR1S1	3795.0
GNB1	3778.0
CALM1	3777.0
FNTB	3742.0
PRKCA	3721.0
SLC24A1	3649.0
TAS2R4	3624.0
OR51G2	3516.0
OR4K17	3453.0
TRPM4	3435.0
OR13G1	3423.0
OR1L8	3411.0
WHRN	3404.0
CACNA1D	3364.0
OR9I1	3322.0
OR5D16	3313.0
OR12D3	3278.0
OR5A1	3239.0
OR10A6	3235.0
OR4A5	3124.0
CAPZB	3073.0
OR10K2	3069.0
AGRN	3030.0
OR4C45	2912.0
OR4K5	2867.0
OR5I1	2855.0
OR6N2	2810.0
TAS2R43	2809.0
OR2H2	2786.0
OR51E1	2767.0
RTP1	2645.0
OR5M11	2627.0
OR4F15	2607.0
TAS2R8	2525.0
OR52A1	2509.0
OR6K2	2471.0
OR1N2	2464.0
OR5AU1	2435.0
GRK1	2365.0
OR56A3	2353.0
PLS1	2352.0
OR2L2	2317.0
OR4C12	2309.5
MYO3B	2306.0
OR2L13	2291.0
OR52E4	2278.0
OR8J1	2274.0
KCNMB1	2230.0
RDH5	2201.0
OTOG	2195.0
OR4K14	1984.0
OR6Q1	1943.0
SLC17A8	1935.0
ESPNL	1842.0
OR6C68	1822.0
SCNN1D	1685.0
OR5AP2	1674.0
OR51A2	1657.0
TPRN	1644.0
OR5L1	1592.0
OR11H6	1409.0
OR7A10	1369.0
GNAT1	1311.0
OR9Q1	1285.0
OR13A1	1267.0
OR10A4	1197.0
OR1L1	1182.0
OR1L4	1150.0
PCDH15	1139.0
KCNMA1	1126.0
OR4A16	1120.0
SLC26A5	1100.0
ABCA4	1089.0
PNLIP	1077.0
AKR1C4	1039.0
RDX	724.0
APOB	682.0
OR6C76	608.0
RGS9	571.0
OR5AK2	559.0
OR8A1	539.0
OR4K13	532.0
CABP1	530.0
LDB1	472.0
OR52K1	426.0
OR1L6	184.0
OR2T11	173.0
TWF1	56.0
GPC5	26.0
OR2B6	21.0
PJVK	8.0
OR10H1	-40.0
ANO2	-91.0
OR2T6	-122.0
OR6N1	-232.0
TRIOBP	-249.0
NMT2	-293.0
OR1B1	-345.0
OR2W1	-453.0
OR2AG1	-497.0
OR13C8	-564.0
RBP2	-615.0
OR2T33	-671.0
LHFPL5	-708.0
OR2G6	-744.0
OR5L2	-940.0
OR5B21	-991.0
METAP2	-1015.0
OR51G1	-1076.0
OR2T12	-1131.0
OR6C70	-1152.0
SPTBN1	-1240.0
OR6C6	-1261.0
LRP2	-1265.0
OR6C3	-1270.0
RAB3A	-1300.0
LDLR	-1310.0
OR5T3	-1518.0
BCO2	-1593.0
OR14C36	-1643.0
OR2M5	-1663.0
OR14I1	-1680.0
GRK4	-1824.0
OR9G1	-1826.5
OR9G9	-1826.5
OR4A47	-1956.0
OR2A5	-2152.0
OR52A5	-2159.0
SCN2B	-2274.0
OR2T8	-2317.0
OR10S1	-2416.0
OR7G1	-2433.0
OR14J1	-2443.0
PRKCQ	-2494.0
NMT1	-2689.0
OR4D6	-2736.0
OR8B4	-2756.0
OR4C16	-2891.0
OR9Q2	-2897.0
GNAL	-2900.0
OR6P1	-3003.0
SCN9A	-3023.0
OR4S1	-3036.0
OR51B5	-3054.0
PCLO	-3101.0
OR5D14	-3113.0
OR1L3	-3155.0
OR7C2	-3191.0
OR5AN1	-3195.0
EPS8	-3264.0
OR51V1	-3316.0
RDH10	-3342.0
OR52E2	-3362.0
GNB5	-3412.0
CYP4V2	-3456.0
GPC6	-3484.0
OR51A7	-3527.0
TMC1	-3545.0
TAS2R3	-3568.0
OR8S1	-3604.0
OR52M1	-3618.0
OR56A4	-3673.0
OR2L8	-3716.0
OR1J4	-3763.0
RIPOR2	-3804.0
OR8U8	-3831.0
TAS2R40	-3925.0
OR2F2	-3957.0
OR1C1	-4012.0
EZR	-4015.0
SCN3A	-4056.0
OTOP1	-4144.0
METAP1	-4158.0
HSD17B1	-4198.0
OR6C74	-4263.0
OR9K2	-4277.0
OR4A15	-4293.0
OR6F1	-4303.0
OR6M1	-4340.0
EPS8L2	-4360.0
RDH12	-4375.0
PDE6A	-4428.0
OR13D1	-4522.0
OR8K3	-4530.0
OR51Q1	-4564.0
OR51I1	-4582.0
OR12D2	-4653.0
OR6C4	-4674.0
OR51L1	-4787.0
SCNN1G	-4866.0
RCVRN	-4980.0
OR51B2	-5108.0
OR5AS1	-5137.0
OR10G4	-5189.0
CACNB2	-5197.0
OTOGL	-5246.0
OR51B4	-5381.0
SCN1B	-5390.0
CAMKMT	-5483.0
OR2M3	-5499.0
OR10P1	-5580.0
SCN4B	-5658.0
OR6A2	-5662.0
OR52B2	-5732.0
OR10A5	-5853.0
RGS9BP	-5863.0
CAPZA1	-5977.0
EPB41L3	-5992.0
OR10G7	-6111.0
BCO1	-6116.0
DHRS9	-6143.0
OR56A1	-6240.0
XIRP2	-6263.0
OR9G4	-6421.0
OR5J2	-6492.0
GRM1	-6545.0
REEP1	-6612.0
MYO3A	-6658.0
OR52K2	-6682.0
OR5B3	-6741.0
CHRNA9	-6756.0
OR51T1	-6763.0
FNTA	-6766.0
LRP12	-6843.0
OR2M7	-6939.0
KCNN2	-7002.0
OR8H1	-7089.0
OR6K3	-7091.0
OR10J3	-7103.0
OR8H3	-7137.0
OR1J2	-7148.0
CAPZA2	-7182.0
TAS2R13	-7236.0
OR4M1	-7340.0
HSD17B6	-7395.0
OR5M9	-7399.0
SDC3	-7400.0
OR10G8	-7493.0
OR6T1	-7526.0
OR10V1	-7549.0
OR5T1	-7586.0
OR4C6	-7629.0
EBF1	-7649.0
OR8D4	-7655.0
ACTG1	-7705.0
OR52B6	-7741.0
OR6B2	-7827.0
SCN2A	-7876.0
OR8K1	-7914.0
OR4K15	-7925.0
RETSAT	-7976.0
RBP4	-7989.0
TMIE	-7995.0
OR1E2	-7998.0
OR10AG1	-8036.0
OR7A17	-8058.0
OR2T3	-8064.0
OR10G2	-8089.0
KCNJ2	-8104.0
OR8K5	-8130.0
GRXCR2	-8225.0
OR8D2	-8240.0
OR10J5	-8383.0
OR5P2	-8400.0
USH1G	-8409.0
SDC2	-8430.0
RBP1	-8440.0
OR10G3	-8489.0
OR10T2	-8590.0
TAS2R16	-8651.0
OR7C1	-8661.0
OR52I1	-8673.0
ESPN	-8765.0
OR2H1	-8831.0
OR9A2	-8846.0
OR1Q1	-8918.0
OR4C3	-8943.0
OR5M10	-9008.0
OR1F1	-9101.0
OR51F1	-9118.0
LHX2	-9171.0
OR1A1	-9182.0
LPL	-9198.0
TAS2R38	-9309.0
GRXCR1	-9343.0
RDH8	-9602.0
OR8B12	-9604.0
OR51S1	-9620.0
OR10H3	-9735.0
OR8G1	-9750.0
OR5P3	-9760.0
GNG13	-9775.0
OR7G3	-9797.0
OR5M8	-9824.0
OR4F6	-9848.0
OR2T4	-9937.0
OR4N5	-9966.0
OR4X1	-10052.0
LRAT	-10076.0
LRRC52	-10084.0
TAS2R1	-10109.0
APOC2	-10151.0
OR5M1	-10208.0
OR4D11	-10214.0
OR52E6	-10286.0
OR10W1	-10296.0
OR2AT4	-10369.0
ACTB	-10373.0
OR10J1	-10451.0
OR10H2	-10572.0
OR10H5	-10600.0
OR56A5	-10613.0
OR51B6	-10618.0
OR1S2	-10623.0
STX1A	-10640.0
OR2L5	-10641.0
OR51F2	-10683.0
OR4C46	-10717.0
OR10G9	-10739.0
OR5A2	-10811.0
OR8G5	-10870.0
OR5B17	-10953.0
OR56B4	-11018.0

---

REACTOME_SELENOAMINO_ACID_METABOLISM

REACTOME_SELENOAMINO_ACID_METABOLISM

	484
set	REACTOME_SELENOAMINO_ACID_METABOLISM
setSize	108
pANOVA	1.26e-05
s.dist	-0.243
p.adjustANOVA	0.00148

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL29	-10734.0
RPS12	-10480.0
GNMT	-10097.0
RPS25	-9996.0
RPL12	-9789.0
RPL23	-9573.0
RPL18	-9396.0
RPL10L	-9192.0
RPL13	-9165.0
RPL10A	-8981.0
RPS13	-8885.0
RPL24	-8697.0
RPS26	-8630.0
RPS6	-8578.0
RPL41	-8474.0
RPS28	-8280.0
RPL13A	-8267.5
RPL14	-8156.0
RPL11	-8150.0
RPL4	-8026.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL29	-10734.0
RPS12	-10480.0
GNMT	-10097.0
RPS25	-9996.0
RPL12	-9789.0
RPL23	-9573.0
RPL18	-9396.0
RPL10L	-9192.0
RPL13	-9165.0
RPL10A	-8981.0
RPS13	-8885.0
RPL24	-8697.0
RPS26	-8630.0
RPS6	-8578.0
RPL41	-8474.0
RPS28	-8280.0
RPL13A	-8267.5
RPL14	-8156.0
RPL11	-8150.0
RPL4	-8026.0
RPL7	-8006.0
RPL39L	-7836.0
FAU	-7687.0
RPL34	-7413.0
RPS15A	-7332.0
LARS1	-7222.0
RPL5	-7169.0
RPSA	-6914.0
RPL36AL	-6833.5
RPL37	-6752.0
RPLP0	-6587.0
RPL23A	-6481.0
RPL35A	-6473.0
PAPSS2	-6376.0
RPL21	-6325.0
RPL22L1	-6284.0
NNMT	-6238.0
RPS3A	-6158.0
RPL17	-5981.0
RPL27A	-5715.0
RPS24	-5677.0
RPL18A	-5525.0
RPS18	-5357.0
RPL35	-5265.0
RPL8	-5017.0
RPS20	-4837.0
RPLP2	-4592.0
UBA52	-4361.0
RPL28	-4300.0
RPS10	-4220.0
RPS11	-4189.0
RPS5	-3903.0
RPL36	-3867.0
RPLP1	-3490.0
RPL15	-3478.0
RARS1	-3393.0
EPRS1	-3352.0
RPS29	-3289.0
SEPHS2	-3217.0
RPL19	-3065.0
RPL9	-2640.0
RPS16	-2594.0
RPL30	-2386.0
SCLY	-2351.0
RPS15	-2337.0
RPL6	-2141.0
RPL3	-1846.0
RPS2	-1664.0
RPS27A	-1544.0
RPL38	-1357.0
RPS8	-1326.0
AIMP1	-1209.0
RPS23	-1205.0
EEF1E1	-1139.0
MARS1	-1103.0
RPL37A	-1087.0
RPS21	-811.0
SEPSECS	-635.0
PAPSS1	-489.0
RPS9	-121.0
RPL32	63.0
KARS1	432.0
DARS1	860.0
RPS7	1873.0
AIMP2	2477.0
IARS1	2625.0
TXNRD1	2669.0
AHCY	3136.0
RPL26L1	3302.0
RPL27	3305.0
RPL26	3766.0
RPS27L	3876.0
SECISBP2	3902.0
PSTK	3963.0
GSR	4098.0
RPL7A	4313.0
HNMT	5654.0
RPL31	7031.0
RPS3	7084.0
MAT1A	7311.0
RPS27	7437.0
CTH	7480.0
RPL22	7534.0
RPS14	7712.0
RPS19	7721.0
EEFSEC	9547.0
RPL3L	9685.0
INMT	9990.0

---

REACTOME_DEVELOPMENTAL_BIOLOGY

REACTOME_DEVELOPMENTAL_BIOLOGY

	76
set	REACTOME_DEVELOPMENTAL_BIOLOGY
setSize	1115
pANOVA	3.15e-05
s.dist	-0.0739
p.adjustANOVA	0.00345

Top enriched genes

Top 20 genes

GeneID	Gene Rank
KRTAP5-1	-11029
TYROBP	-11000
LCE2B	-10995
KRTAP3-3	-10938
KRTAP19-8	-10915
HOXB2	-10908
SPRR2E	-10867
KRT17	-10818
NANOG	-10800
KRTAP2-4	-10774
KRTAP19-4	-10759
NTN3	-10753
RPL29	-10734
DPPA4	-10721
KRTAP4-11	-10708
LCE1F	-10664
STX1A	-10640
KLK5	-10594
KRT33B	-10568
RPS12	-10480

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
KRTAP5-1	-11029.0
TYROBP	-11000.0
LCE2B	-10995.0
KRTAP3-3	-10938.0
KRTAP19-8	-10915.0
HOXB2	-10908.0
SPRR2E	-10867.0
KRT17	-10818.0
NANOG	-10800.0
KRTAP2-4	-10774.0
KRTAP19-4	-10759.0
NTN3	-10753.0
RPL29	-10734.0
DPPA4	-10721.0
KRTAP4-11	-10708.0
LCE1F	-10664.0
STX1A	-10640.0
KLK5	-10594.0
KRT33B	-10568.0
RPS12	-10480.0
KRTAP12-1	-10444.0
KRTAP24-1	-10387.0
ACTB	-10373.0
GATA2	-10325.0
H2AC20	-10322.0
LCE6A	-10298.0
MED20	-10176.0
SCN11A	-10154.0
KRTAP9-3	-10145.0
INSM1	-10134.0
KRTAP5-2	-10125.0
POU3F2	-10115.0
KRTAP13-1	-10113.0
CDON	-10028.0
WNT10B	-10019.0
KRTAP21-1	-9999.0
RPS25	-9996.0
TNF	-9974.0
RRAS	-9930.0
ONECUT1	-9919.0
MAGOH	-9876.0
MEIS1	-9873.0
LCE3E	-9863.0
CLTA	-9790.0
RPL12	-9789.0
PDX1	-9784.0
TREM2	-9736.0
UBB	-9702.0
TUBB6	-9696.0
KRTAP5-4	-9692.0
KRTAP9-6	-9684.0
CEBPA	-9666.0
PTPN11	-9664.0
LCE2D	-9657.0
H2AX	-9652.0
FOXL2	-9599.0
IL6R	-9582.0
RPL23	-9573.0
CNTN6	-9568.0
HSPA8	-9533.0
CDK4	-9528.0
KRT2	-9520.0
PRDM14	-9466.0
TEAD2	-9436.0
PIK3R2	-9426.0
POLR2K	-9413.0
CACNG8	-9400.0
RPL18	-9396.0
H4C8	-9377.0
CD72	-9372.0
PAGR1	-9368.0
PSMC4	-9362.0
IVL	-9308.0
CXCL12	-9306.0
GFRA3	-9291.0
EFNA4	-9282.0
KRTAP9-9	-9281.0
MED7	-9269.0
EFNA2	-9254.0
HOXD4	-9244.0
HHEX	-9241.0
DKK1	-9219.0
NKX2-2	-9214.0
NRAS	-9202.0
LPL	-9198.0
RPL10L	-9192.0
WNT1	-9185.0
LHX2	-9171.0
RPL13	-9165.0
CDH1	-9135.0
PPARG	-9074.0
H3-3A	-9072.0
H2BC21	-9064.0
COL4A4	-9050.0
APH1B	-9040.0
PPP3CB	-9019.0
ONECUT3	-8989.0
RPL10A	-8981.0
KRTAP5-5	-8962.0
LIPJ	-8944.0
MAFA	-8929.0
NOG	-8917.0
DOK5	-8899.0
H2BC5	-8892.0
RPS13	-8885.0
LGI2	-8883.0
NOTO	-8855.0
TUBA3E	-8829.0
PSMA8	-8792.0
FABP4	-8767.0
PAX6	-8761.0
TUBA1B	-8749.0
DSC2	-8742.0
KLK8	-8740.0
FOXA1	-8721.0
HOXA1	-8713.0
YAP1	-8707.0
LCE2A	-8698.0
RPL24	-8697.0
MED1	-8676.0
RPS26	-8630.0
RAC1	-8610.0
TUBB4B	-8604.0
RPS6	-8578.0
MED6	-8572.0
HOXB3	-8559.0
EFNB3	-8552.0
PKP2	-8546.0
KRTAP5-3	-8506.0
OCLN	-8485.0
MED13L	-8476.0
RPL41	-8474.0
RBM8A	-8468.0
CHL1	-8444.0
CDH2	-8441.0
H4C3	-8439.0
SDC2	-8430.0
SHH	-8429.0
DSC3	-8362.0
ETF1	-8311.0
RPS28	-8280.0
RPL13A	-8267.5
CAP2	-8255.0
KAT2B	-8201.0
NKX6-1	-8192.0
SOX2	-8177.0
MED9	-8172.0
RPL14	-8156.0
RPL11	-8150.0
DMRT1	-8096.0
PLIN1	-8095.0
UNC5C	-8086.0
KRTAP4-6	-8049.0
RPL4	-8026.0
MED21	-8016.0
RPL7	-8006.0
LHX9	-8002.0
H3C10	-7994.0
UBC	-7974.0
TUBB2A	-7957.0
LCE3A	-7954.0
SALL1	-7946.0
TAL1	-7932.0
SCN2A	-7876.0
H2BC11	-7869.0
ACVR2A	-7855.0
PSMD12	-7843.0
RPL39L	-7836.0
SHC1	-7816.0
EFNA1	-7769.0
LCE3D	-7762.0
FOXO1	-7760.0
COL4A3	-7747.0
SCN8A	-7731.0
MAPK1	-7718.0
ACTG1	-7705.0
FAU	-7687.0
EBF1	-7649.0
MIXL1	-7646.0
KRTAP5-6	-7636.0
ADGRV1	-7616.0
ST8SIA4	-7583.0
KRT20	-7554.0
H2BC14	-7552.0
KRTAP21-3	-7539.0
EOMES	-7529.0
HOXC4	-7514.0
GATA4	-7503.0
EPHA7	-7498.0
KRTAP5-7	-7490.0
PSMB10	-7431.0
FOXF1	-7421.0
PSMC5	-7419.0
RPL34	-7413.0
POLR2L	-7397.0
KRTAP10-11	-7382.0
POLR2D	-7349.0
RPS15A	-7332.0
ELOC	-7318.0
SPRR2G	-7316.0
LYN	-7312.0
FURIN	-7294.0
HNF4G	-7283.0
MED19	-7280.0
H2BC17	-7263.0
VLDLR	-7252.0
ADAM11	-7250.0
IAPP	-7230.0
FGF9	-7195.0
SCN1A	-7193.0
RPL5	-7169.0
LGI1	-7164.0
CNTN1	-7155.0
GDNF	-7136.0
LHX3	-7113.0
KRT27	-7111.0
PSMB4	-7098.0
ST8SIA2	-7092.0
H2BC4	-7072.0
WNT3A	-7048.0
HOXB4	-7020.0
DRAP1	-6985.0
KRTAP12-4	-6984.0
GFI1	-6983.0
YES1	-6977.0
H3-3B	-6937.0
RPS6KA1	-6926.0
RPSA	-6914.0
CELA2A	-6875.0
DSG3	-6869.0
CTNNA2	-6868.0
TUBB8	-6855.0
MYL12A	-6848.0
MYL12B	-6845.0
RPL36AL	-6833.5
CSTA	-6830.0
KLF4	-6815.0
HSP90AB1	-6813.0
COL6A5	-6792.0
H3C2	-6790.0
HES1	-6760.0
PSME4	-6754.0
RPL37	-6752.0
NEUROG3	-6746.0
KRTAP19-5	-6728.0
ITGA9	-6725.0
COL5A3	-6711.0
DLL3	-6691.0
H2AJ	-6672.0
EPHA3	-6659.0
IHH	-6653.0
KRTAP27-1	-6652.0
KRTAP12-3	-6609.0
MED11	-6591.0
H2BC13	-6590.0
RPLP0	-6587.0
LHX4	-6583.0
KCNQ3	-6579.0
HDAC2	-6547.0
KRT26	-6522.0
POLR2I	-6513.0
SEMA6D	-6505.0
CDX2	-6504.0
TUBB4A	-6499.0
PBX1	-6490.0
RPL23A	-6481.0
KRTAP1-5	-6480.0
RPL35A	-6473.0
H2AC8	-6445.0
GAB1	-6416.0
PCK1	-6412.0
DSG4	-6374.0
SPINK6	-6362.0
FGF10	-6358.0
COL9A1	-6330.0
RPL21	-6325.0
KRT80	-6324.0
KRTAP21-2	-6322.0
SNW1	-6319.0
HMGCR	-6306.0
HJV	-6292.0
RPL22L1	-6284.0
MAPK14	-6253.0
H2AC7	-6250.5
H2BC7	-6250.5
ITGA5	-6235.0
GAB2	-6223.0
TUBB2B	-6175.0
RPS3A	-6158.0
NCOA2	-6134.0
LIMK1	-6124.0
DAB1	-6123.0
H2AC6	-6100.0
PSMC2	-6092.0
PSME2	-6084.0
SMAD4	-6076.0
SLIT2	-6063.0
RARG	-6058.0
ADGRG6	-6038.0
PTPRC	-6035.0
HSP90AA1	-6002.0
CDK2	-6001.0
H2BC8	-5989.0
PSMA3	-5986.0
RPL17	-5981.0
SCN3B	-5944.0
NTN4	-5928.0
SH3GL2	-5875.0
TUBB3	-5860.0
SEMA3E	-5856.0
PSMB8	-5844.0
EPHA10	-5840.0
MAML1	-5839.0
TSC22D1	-5819.0
SLC2A4	-5801.0
EFNB2	-5791.0
CHD9	-5790.0
CCND3	-5768.0
PIK3R1	-5752.0
RPL27A	-5715.0
H2AC18	-5704.5
H2AC19	-5704.5
RPS24	-5677.0
SCN4B	-5658.0
DOK2	-5632.0
ABLIM3	-5595.0
FES	-5574.0
MEF2C	-5570.0
H3C4	-5557.0
DPYSL4	-5549.0
TCF4	-5548.0
RPL18A	-5525.0
GRIN1	-5515.0
KRTAP10-5	-5507.0
MED4	-5496.0
RNPS1	-5489.0
PAXIP1	-5485.0
H2AC14	-5481.0
SPRR2A	-5469.0
MET	-5427.0
EFNA5	-5421.0
SCN1B	-5390.0
LCE1A	-5375.0
RPS18	-5357.0
RPL35	-5265.0
TUBA1C	-5216.0
CACNB2	-5197.0
NCBP2	-5148.0
NRP2	-5131.0
KRT10	-5113.0
H3C12	-5090.0
SALL4	-5063.0
MED10	-5044.0
CTCF	-5033.0
FYN	-5019.0
RPL8	-5017.0
ADAM22	-5014.0
THRAP3	-4947.0
APH1A	-4917.0
KRT75	-4892.0
ACTR2	-4881.0
HNF1B	-4868.0
RPS20	-4837.0
DNM3	-4834.0
ELOB	-4810.0
KLK13	-4784.0
CACNG2	-4774.0
WT1	-4764.0
HOXD1	-4699.0
EPHA5	-4694.0
DSG2	-4662.0
RARB	-4644.0
COL9A3	-4628.0
KRT38	-4619.0
SMAD3	-4614.0
PSEN2	-4610.0
NCK1	-4603.0
RPS6KA5	-4598.0
RPLP2	-4592.0
PPARGC1A	-4586.0
KRTAP1-1	-4571.0
CLTC	-4494.0
CLDN7	-4474.0
TGS1	-4456.0
GSPT1	-4445.0
PSMA5	-4438.0
TRPC4	-4429.0
RARA	-4410.0
RELN	-4399.0
BMP4	-4389.0
UBA52	-4361.0
PSMD11	-4325.0
UNC5D	-4324.0
UTRN	-4302.0
RPL28	-4300.0
PFN1	-4292.0
PSMD5	-4244.0
RBBP4	-4237.0
RPS10	-4220.0
FOXH1	-4219.0
H2BC6	-4207.0
WASL	-4194.0
RPS11	-4189.0
KRTAP4-7	-4168.0
H4C6	-4120.0
CASC3	-4102.0
KRTAP5-10	-4078.0
SDCBP	-4069.0
SCN3A	-4056.0
DHH	-4051.0
SPI1	-4047.0
ARHGEF12	-4025.0
PERP	-4024.0
AP2B1	-4018.0
EZR	-4015.0
ARPC5	-4011.0
KRT28	-4006.0
MED24	-3995.0
PSMD9	-3987.0
POLR2C	-3916.0
NEO1	-3910.0
RPS5	-3903.0
RUNX1	-3889.0
RBPJ	-3875.0
RPL36	-3867.0
TUBA1A	-3854.0
GSC	-3852.0
MYC	-3827.0
RHOC	-3818.0
H3C11	-3817.0
ADAM23	-3771.0
KMT2A	-3737.0
MED8	-3735.0
AKAP5	-3727.0
GRB7	-3707.0
PAK1	-3644.0
LAMB1	-3602.0
PRKACB	-3597.0
BOC	-3589.0
RPLP1	-3490.0
DOK6	-3481.0
RPL15	-3478.0
KALRN	-3477.0
KLK12	-3463.0
DSP	-3433.0
PSMA6	-3425.0
MED28	-3424.0
EGR2	-3304.0
RPS29	-3289.0
RFX6	-3282.0
KRTAP20-1	-3276.0
PIAS2	-3274.0
SPRR2F	-3270.0
KRTAP29-1	-3243.0
EIF4G1	-3228.0
KRT40	-3223.0
NFKB1	-3211.0
PIK3R3	-3209.0
KRTAP10-3	-3201.0
MEF2D	-3171.0
SEMA4A	-3141.0
RBX1	-3122.0
ROBO2	-3112.0
H4C13	-3097.0
LAMC1	-3091.0
PSMC1	-3076.0
RBBP5	-3068.0
RPL19	-3065.0
PSME3	-3024.0
SCN9A	-3023.0
CACNB4	-3022.0
GRB2	-2984.0
GSK3B	-2980.0
PSMB9	-2972.0
KRTAP6-3	-2961.0
ROBO1	-2938.0
MAML2	-2936.0
VAV3	-2932.0
ROBO3	-2930.0
NR6A1	-2925.0
RASA1	-2923.0
SEMA5A	-2908.0
PRKAR2A	-2896.0
MED29	-2895.0
CRMP1	-2890.0
DPYSL5	-2834.0
CDC42	-2824.0
YY1	-2808.0
SOS2	-2743.0
AJUBA	-2740.0
PMP22	-2723.0
MYO10	-2716.0
ARPC4	-2710.0
NCAN	-2678.0
LYPLA2	-2656.0
EPHB1	-2646.0
RPL9	-2640.0
EGFR	-2625.0
CREB1	-2614.0
CACNB3	-2599.0
RPS16	-2594.0
STAT3	-2557.0
PRKCQ	-2494.0
MED26	-2475.0
NAB1	-2466.0
NCSTN	-2437.0
LEFTY2	-2402.0
RPL30	-2386.0
HOXD3	-2379.0
DAND5	-2364.0
ACVR1C	-2350.0
TBPL2	-2343.0
RPS15	-2337.0
SCN2B	-2274.0
RGMB	-2241.0
ANK2	-2235.0
H2AZ2	-2221.0
ALCAM	-2220.0
KRTAP26-1	-2214.0
RPL6	-2141.0
PSMD1	-2120.0
DSCAM	-2107.0
SPRR2D	-2088.0
LIN28A	-2084.0
NCOA6	-2049.0
TIAM1	-2035.0
KRT72	-2023.0
ACVR2B	-2017.0
ADIRF	-2012.0
PSENEN	-1995.0
CLASP2	-1949.0
LCE4A	-1943.0
TRPC6	-1930.0
FOXA2	-1906.0
MAPK13	-1892.0
DSG1	-1889.0
KRTAP6-1	-1849.0
RPL3	-1846.0
SRGAP1	-1830.0
LIMK2	-1821.0
KRTAP1-3	-1798.0
KRTAP9-4	-1780.0
PSMB5	-1772.0
SHTN1	-1767.0
KRT76	-1735.0
RPS2	-1664.0
KRT37	-1641.0
ABLIM1	-1639.0
SPRR1A	-1586.0
ASH2L	-1576.0
SOX9	-1552.0
SLIT1	-1546.0
PSMA1	-1545.0
RPS27A	-1544.0
CSNK2B	-1533.0
H2AZ1	-1527.0
MMP9	-1485.0
MAML3	-1443.0
FLI1	-1414.0
LAMA2	-1404.0
FOXP1	-1397.0
MED31	-1394.0
KRAS	-1382.0
PSMB3	-1361.0
RPL38	-1357.0
RPS8	-1326.0
PSEN1	-1262.0
NR2F2	-1256.0
SPTBN1	-1240.0
GFRA1	-1237.0
KRTAP3-2	-1217.0
RPS23	-1205.0
DCC	-1195.0
H4C2	-1183.0
ROCK2	-1173.0
RPL37A	-1087.0
KRTAP10-10	-1085.0
TBXT	-1083.0
KRTAP4-3	-1079.0
GRIN2B	-1066.0
CBFB	-1044.0
MBP	-1042.0
ROCK1	-1011.0
KRTAP19-3	-1002.0
GRB10	-889.0
PAX4	-871.0
FLG	-841.0
UPF3A	-824.0
RPS21	-811.0
SLIT3	-772.0
CFL1	-741.0
H4C1	-737.0
CTNNA1	-735.0
RAP1GAP	-721.0
CDH15	-720.0
PIK3CA	-717.0
ARPC2	-698.0
DLG4	-682.0
CSNK2A1	-662.0
ZFPM2	-661.0
PSME1	-658.0
PLXNC1	-648.0
FOXD3	-631.0
H4C5	-618.0
UNC5A	-614.0
SPTBN4	-588.0
CD36	-543.0
GATA6	-535.0
PTPRA	-532.0
SEMA3A	-503.0
PABPC1	-486.0
MYOD1	-461.0
ARHGEF28	-408.0
KRTAP2-2	-404.0
GFRA4	-403.0
DNM1	-402.0
COL2A1	-389.0
NCBP1	-381.0
CNTNAP1	-376.0
H2BC15	-371.0
MYB	-365.0
MEF2B	-314.0
ARHGAP35	-310.0
TUBA4B	-299.0
TBX6	-285.0
PTF1A	-260.0
RANBP9	-244.0
KRTAP19-7	-234.0
KRT1	-182.0
TBL1XR1	-134.0
RPS9	-121.0
ITGB1	-101.0
ABL1	-86.0
H2BC1	-54.0
MAPK7	-30.0
KCNQ2	-18.0
EPHA1	-11.0
SEM1	-1.0
SHC3	13.0
RPL32	63.0
LCE3B	65.0
POLR2B	117.0
CNOT9	125.0
ACVR1B	126.0
CACNA1C	156.0
KRTAP9-2	180.0
CNOT6	187.0
PRX	198.0
PPL	216.0
ITGB3	248.0
WNT4	291.0
UPF2	298.0
PSMD8	315.0
MAP2K1	378.0
JUN	408.0
TGM5	420.0
KRTAP12-2	421.0
ITGA1	433.0
CSNK2A2	438.0
LDB1	472.0
EFNA3	511.0
CASP14	574.0
JUP	578.0
NELL2	580.0
KRT6A	589.0
CDKN1A	606.0
PFN2	613.0
MYL6	657.0
H2BC12	672.0
TUBA3C	701.0
MPZ	706.0
TEAD1	707.0
RDX	724.0
KRT12	734.0
MAPK12	754.0
CDK19	758.0
EP300	781.0
KRTAP2-1	799.0
SIAH1	854.0
MYF5	867.0
DOCK1	898.0
POLR2G	936.0
PSMA7	942.0
EPHA2	973.0
PAK5	982.0
PSMA2	1059.0
MAP2K6	1098.0
NRCAM	1131.0
PSMD7	1158.0
ARTN	1164.0
ENAH	1198.0
ITGA10	1216.0
KLF5	1243.0
ADAM10	1278.0
TRPC1	1315.0
CAPN1	1356.0
SPAG9	1367.0
KRT6C	1411.0
DPYSL3	1419.0
PLXNA4	1456.0
KRTAP10-1	1483.0
KRTAP20-2	1484.0
ARPC3	1491.0
PSMB2	1566.0
TCHH	1578.0
CXCR4	1582.0
ARPC1A	1584.0
KRTAP13-4	1589.0
EPHA6	1593.0
MED23	1632.0
MAFB	1665.0
RHOA	1702.0
GDF1	1706.0
CDK5	1717.0
HELZ2	1738.0
LAMA1	1758.0
PTK2	1793.0
KMT2C	1821.0
HDAC3	1872.0
RPS7	1873.0
NCK2	1876.0
NCOR1	1885.0
TUBA8	1901.0
FAM120B	1963.0
DNM2	2057.0
EED	2064.0
POLR2E	2087.0
NAB2	2118.0
SPRR1B	2124.0
RET	2149.0
PIK3CD	2150.0
ERBB2	2158.0
FGFR1	2177.0
NR5A2	2192.0
CUL2	2205.0
GAP43	2223.0
MMP2	2239.0
KRTAP4-1	2260.0
STX1B	2286.0
BNIP2	2289.0
LEF1	2307.0
ANGPTL4	2327.0
MSI1	2338.0
DLL1	2367.0
PSMD14	2369.0
SPINK5	2413.0
SEMA7A	2429.0
COL4A1	2436.0
PKP4	2438.0
FOXA3	2486.0
NR5A1	2527.0
CACNA1H	2700.0
CAP1	2748.0
SCN7A	2762.0
LCE1E	2772.0
PSMC3	2777.0
POLR2H	2784.0
CACNA1G	2790.0
ISL1	2851.0
ITGA2B	2935.0
NODAL	2940.0
H2AC4	2947.0
KRT7	2960.0
MAPK11	2972.0
CLASP1	2993.0
ZNF467	3017.0
GIT1	3020.0
COL5A2	3027.0
AGRN	3030.0
DOK1	3075.0
FOXO3	3101.0
EZH2	3126.0
LIPM	3152.0
TRPC3	3155.0
SPTA1	3161.0
MED17	3180.0
H4C16	3253.0
WWTR1	3261.0
EPHA4	3294.0
RPL26L1	3302.0
PSMD13	3304.0
RPL27	3305.0
LIPN	3308.0
KRTAP15-1	3316.0
MAPK8	3348.0
CACNA1D	3364.0
ACTR3	3379.0
SOS1	3385.0
PCGF2	3422.0
E2F1	3427.0
ABL2	3439.0
CTNNB1	3514.0
LCE1C	3524.0
PSMB7	3558.0
CACNG3	3636.0
PSMD4	3642.0
PSMD2	3699.0
PRKCA	3721.0
AMH	3740.0
HIF3A	3750.0
RPL26	3766.0
TGFB1	3769.0
RXRA	3824.0
NGEF	3829.0
AKT3	3841.0
SIAH2	3855.0
RPS27L	3876.0
FLRT3	3878.0
MED13	3912.0
CDK8	3969.0
KRTAP10-9	4000.0
UNC5B	4015.0
DPYSL2	4018.0
PSMA4	4073.0
NCOA3	4077.0
LEP	4099.0
KRTAP19-1	4150.0
KRT24	4212.0
NCOA1	4237.0
SCD5	4248.0
H3C1	4262.0
NRP1	4306.0
SMAD2	4309.0
RPL7A	4313.0
EPHA8	4341.0
PRKACA	4352.0
KAZN	4378.0
PKNOX1	4379.0
KRTAP19-6	4405.0
KRT16	4422.0
MYH10	4427.0
ADIPOQ	4441.0
PSMC6	4442.0
POU3F1	4446.0
COL4A2	4461.0
SMARCD3	4464.0
PSMD6	4479.0
MEF2A	4487.0
MED15	4488.0
MED22	4493.0
PTGDS	4526.0
RPS6KA2	4563.0
H2BC26	4643.0
ITGA2	4645.0
HOXA4	4671.0
IRS2	4801.0
DLG1	4811.0
TRIM33	4812.0
NUMB	4827.0
KRT25	4847.0
ST14	4897.0
MYL9	4904.0
PITPNA	4905.0
NCOR2	4914.0
COL6A6	4931.0
MAGOHB	4952.0
AP2A2	4969.0
KRTAP6-2	4988.0
DAG1	5020.0
MYH14	5025.0
PAK6	5036.0
DEK	5037.0
MSGN1	5040.0
CACNG4	5099.0
KRT18	5106.0
CACNA1I	5118.0
CLTCL1	5141.0
ANK3	5172.0
CYP51A1	5181.0
PSMB6	5196.0
PSMF1	5201.0
VASP	5207.0
NTN1	5216.0
H4C9	5218.0
ABLIM2	5225.0
KRTAP9-1	5236.0
H2BC9	5307.5
H3C7	5307.5
SPRR3	5331.0
ARHGAP39	5340.0
PSMB1	5414.0
ARPC1B	5423.0
PLXND1	5447.0
KRTAP4-5	5450.0
CAPNS1	5451.0
ARHGEF7	5458.0
HNF4A	5465.0
MYH9	5470.0
TCF7	5475.0
FGF2	5483.0
KRTAP23-1	5502.0
TUBA4A	5539.0
PAK2	5575.0
SRGAP3	5588.0
CEBPD	5604.0
KRTAP13-3	5617.0
USP33	5663.0
EIF4A3	5714.0
FARP2	5848.0
PI3	5856.0
PSPN	5962.0
ANK1	5975.0
ZNF638	5997.0
TCF12	5998.0
PAK4	6006.0
ITSN1	6019.0
DSCAML1	6021.0
RGMA	6026.0
FRS2	6075.0
CEBPB	6090.0
AGAP2	6095.0
AP2A1	6097.0
MED18	6137.0
SPINK9	6148.0
CDK5R1	6149.0
CCNC	6191.0
MAPK3	6201.0
SPTB	6215.0
KIF4B	6289.0
KRT34	6342.0
ITGAV	6399.0
KRTAP4-4	6448.0
PCSK6	6452.0
KRTAP13-2	6457.0
COL9A2	6463.0
CDSN	6491.0
MAP2K2	6502.0
MYF6	6515.0
COL6A1	6522.0
H4C4	6524.0
PPARA	6536.0
KRTAP10-6	6537.0
TRIO	6556.0
ZNF335	6593.0
NEUROD1	6601.0
H3C6	6602.0
GFRA2	6627.0
TRPC7	6648.0
SLC2A2	6652.0
POLR2F	6656.0
LELP1	6689.0
KRT39	6705.0
KRTAP8-1	6711.0
PML	6714.0
KRT8	6746.0
HOXA2	6767.0
NOTCH1	6821.0
KRT33A	6827.0
DOK4	6840.0
EPHB4	6858.0
SPTBN2	6875.0
KRTAP17-1	6900.0
PIK3CB	6910.0
COL3A1	6950.0
PKP1	6973.0
EPHB2	6974.0
KRTAP11-1	7008.0
RPL31	7031.0
KLK14	7080.0
RPS3	7084.0
SEMA6A	7135.0
PLXNA2	7142.0
KRTAP16-1	7155.0
TFDP2	7179.0
CACNB1	7202.0
NFASC	7207.0
EVPL	7223.0
MYH11	7229.0
NCAM1	7268.0
COL6A3	7272.0
CNTN2	7306.0
ARHGEF11	7334.0
LGI3	7350.0
SREBF2	7351.0
H4C12	7358.0
EPAS1	7371.0
PLXNB1	7389.0
KRT14	7410.0
RPS27	7437.0
KRT85	7449.0
MED25	7478.0
RPL22	7534.0
MED16	7560.0
PKP3	7607.0
SEMA4D	7643.0
RELA	7644.0
LCE1B	7662.0
RPS6KA4	7676.0
RPS14	7712.0
RPS19	7721.0
POLR2A	7751.0
AP2M1	7773.0
AKT1	7830.0
KRTAP19-2	7838.0
TLN1	7849.0
KRTAP10-4	7855.0
KRT19	7859.0
KRTAP4-8	7919.0
SNAI1	8034.0
KRTAP22-1	8039.0
AP2S1	8082.0
KAT2A	8115.0
EVL	8119.0
PSMD3	8120.0
TUBAL3	8192.0
SPTAN1	8195.0
GCK	8197.0
TEAD4	8219.0
H2BC3	8253.0
TUBB1	8278.0
HOXB1	8290.0
PRNP	8403.0
HRAS	8450.0
MED27	8481.0
EPHB3	8508.0
CER1	8545.0
PDLIM7	8546.0
CDH4	8637.0
GPC1	8651.0
KRT32	8684.0
SRC	8731.0
WDR5	8748.0
MYO9B	8756.0
MED30	8812.0
PIP5K1C	8846.0
KRT83	8891.0
KRT82	8892.0
MAG	8893.0
HOXA3	8938.0
KRT3	8946.0
RPTN	8969.0
PLCG1	9033.0
EPHB6	9040.0
CREBBP	9058.0
RHOB	9102.0
CSF3R	9112.0
SRGAP2	9117.0
H3C3	9119.0
SREBF1	9158.0
H2BC10	9234.0
KRTAP25-1	9239.0
COL5A1	9262.0
RND1	9278.0
SMARCA4	9287.0
SUZ12	9312.0
KRT15	9354.0
TFDP1	9373.0
LCE2C	9415.0
KRTAP5-9	9424.0
KRT31	9446.0
KRTAP10-8	9502.0
ZSWIM8	9560.0
KRTAP3-1	9573.0
H4C11	9599.0
AKT2	9642.0
KRT73	9645.0
KRTAP10-12	9663.0
RPL3L	9685.0
KRTAP10-7	9693.0
KRT9	9740.0
POLR2J	9748.0
SCN5A	9760.0
KRT5	9783.0
KRTAP1-4	9796.0
PSMB11	9803.0
KRT86	9810.0
KRT35	9813.0
KRT81	9820.0
SCN10A	9862.0
LIPK	9865.0
CARM1	9874.0
H3C8	9880.0
KRT4	9899.0
KRT6B	9915.0
LGI4	9925.0
KRT13	9929.0
CLTB	9932.0
KRTAP5-11	9976.0
KMT2D	9986.0
KRT74	10028.0
VAV2	10056.0
SCN4A	10068.0
COL6A2	10093.0
KRT78	10102.0
KRTAP2-3	10114.0
SPTBN5	10197.0
TUBA3D	10241.0
MYOG	10242.0
KRT71	10245.0
HNF1A	10253.0
LCE5A	10254.0
KRT36	10271.0
KRT77	10276.0
PRKACG	10288.0
INS	10301.0
KRT84	10303.0
ZSCAN10	10334.0
KRT23	10347.0
MESP2	10373.0
POU5F1	10392.0
TCF3	10398.0
PRSS8	10410.0
KRT79	10437.0
PLXNA1	10442.0
CACNA1S	10444.0
CEBPE	10497.0
PKLR	10533.0
TGM1	10549.0
KRTAP4-2	10554.0
SOX10	10597.0
NRTN	10645.0
DSC1	10741.0
LEFTY1	10772.0
KRTAP10-2	10825.0
KRTAP5-8	10927.0

---

REACTOME_RRNA_PROCESSING

REACTOME_RRNA_PROCESSING

	1148
set	REACTOME_RRNA_PROCESSING
setSize	192
pANOVA	3.42e-05
s.dist	-0.173
p.adjustANOVA	0.00351

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL29	-10734
RPS12	-10480
RRP9	-10014
RPS25	-9996
UTP11	-9836
RPL12	-9789
RPL23	-9573
UTP4	-9521
RRP36	-9485
RPL18	-9396
IMP3	-9307
BYSL	-9275
RPL10L	-9192
RPL13	-9165
RPL10A	-8981
RPS13	-8885
RPL24	-8697
RPS26	-8630
LTV1	-8598
RPS6	-8578

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL29	-10734.0
RPS12	-10480.0
RRP9	-10014.0
RPS25	-9996.0
UTP11	-9836.0
RPL12	-9789.0
RPL23	-9573.0
UTP4	-9521.0
RRP36	-9485.0
RPL18	-9396.0
IMP3	-9307.0
BYSL	-9275.0
RPL10L	-9192.0
RPL13	-9165.0
RPL10A	-8981.0
RPS13	-8885.0
RPL24	-8697.0
RPS26	-8630.0
LTV1	-8598.0
RPS6	-8578.0
TRMT10C	-8497.0
RPL41	-8474.0
RPS28	-8280.0
RPL13A	-8267.5
DDX21	-8215.0
RPL14	-8156.0
RPL11	-8150.0
RPL4	-8026.0
RPL7	-8006.0
UTP6	-7983.0
RPL39L	-7836.0
MPHOSPH10	-7780.0
FAU	-7687.0
ERI1	-7618.0
WDR75	-7582.0
RPL34	-7413.0
RPS15A	-7332.0
DCAF13	-7188.0
RPL5	-7169.0
EXOSC5	-7041.0
UTP20	-6969.0
RPSA	-6914.0
RPL36AL	-6833.5
RIOK3	-6831.0
RBM28	-6765.0
RPL37	-6752.0
FTSJ3	-6656.0
RPLP0	-6587.0
RPL23A	-6481.0
RPL35A	-6473.0
RPL21	-6325.0
MPHOSPH6	-6314.0
RPL22L1	-6284.0
RPS3A	-6158.0
RPL17	-5981.0
PNO1	-5905.0
RPL27A	-5715.0
NOP58	-5712.0
GAR1	-5682.0
RPS24	-5677.0
NOL6	-5586.0
RPL18A	-5525.0
RPS18	-5357.0
NOL11	-5333.0
RPL35	-5265.0
NCL	-5085.0
RPL8	-5017.0
XRN2	-4977.0
PDCD11	-4902.0
RPS20	-4837.0
NOL12	-4700.0
RPLP2	-4592.0
UTP3	-4446.0
UBA52	-4361.0
RPL28	-4300.0
RPP30	-4260.0
RPP25	-4250.0
RPS10	-4220.0
RPS11	-4189.0
EXOSC3	-4085.0
ISG20L2	-4058.0
RPS5	-3903.0
RPL36	-3867.0
EXOSC8	-3710.0
RRP1	-3697.0
CSNK1E	-3631.0
RPLP1	-3490.0
RPL15	-3478.0
TRMT112	-3360.0
RIOK2	-3325.0
WDR3	-3291.0
RPS29	-3289.0
THUMPD1	-3285.0
EXOSC7	-3252.0
EXOSC1	-3185.0
RPL19	-3065.0
WDR36	-2844.0
RPL9	-2640.0
RPS16	-2594.0
RPP40	-2575.0
UTP18	-2482.0
RPP38	-2473.0
KRR1	-2432.0
MRM1	-2429.0
RPL30	-2386.0
RPS15	-2337.0
RPP21	-2207.0
NOP56	-2196.0
RPL6	-2141.0
GNL3	-2134.0
NAT10	-2123.0
RPL3	-1846.0
RPS2	-1664.0
RPS27A	-1544.0
WDR12	-1535.0
MTREX	-1433.0
MRM3	-1400.0
RPL38	-1357.0
RPS8	-1326.0
RPS23	-1205.0
RPL37A	-1087.0
NOB1	-975.0
RPS21	-811.0
DIMT1	-764.0
PRORP	-496.0
NIP7	-336.0
DIS3	-214.0
RPS9	-121.0
BMS1	9.0
FCF1	60.0
RPL32	63.0
WDR43	128.0
RPP14	284.0
HEATR1	297.0
EMG1	480.0
C1D	504.0
SNU13	663.0
UTP25	761.0
NHP2	857.0
RPS7	1873.0
NSUN4	1899.0
NOP2	1958.0
PELP1	2019.0
EXOSC9	2285.0
MTERF4	2335.0
DDX47	2392.0
EBNA1BP2	2422.0
UTP15	2499.0
NOC4L	2726.0
WDR46	2848.0
RPL26L1	3302.0
RPL27	3305.0
DDX52	3578.0
RPL26	3766.0
RPS27L	3876.0
RIOK1	3928.0
RPL7A	4313.0
MRM2	4371.0
NOP10	4382.0
FBL	4725.0
TFB1M	4733.0
IMP4	4740.0
BUD23	5056.0
NOL9	5174.0
DDX49	5206.0
PES1	5213.0
TSR1	5543.0
NOP14	6055.0
EXOSC4	6081.0
BOP1	6131.0
RCL1	6429.0
CSNK1D	6698.0
RPL31	7031.0
RPS3	7084.0
PWP2	7107.0
TSR3	7198.0
RPS27	7437.0
RPL22	7534.0
RPS14	7712.0
RPS19	7721.0
EXOSC2	7893.0
WDR18	8495.0
SENP3	8517.0
ELAC2	8529.0
EXOSC6	9038.0
TEX10	9054.0
TBL3	9211.0
DHX37	9292.0
UTP14C	9487.0
RPL3L	9685.0
EXOSC10	10158.0
RRP7A	10441.0

---

REACTOME_SIGNALING_BY_ROBO_RECEPTORS

REACTOME_SIGNALING_BY_ROBO_RECEPTORS

	605
set	REACTOME_SIGNALING_BY_ROBO_RECEPTORS
setSize	206
pANOVA	4.49e-05
s.dist	-0.165
p.adjustANOVA	0.00434

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL29	-10734
RPS12	-10480
RPS25	-9996
MAGOH	-9876
RPL12	-9789
UBB	-9702
RPL23	-9573
RPL18	-9396
PSMC4	-9362
CXCL12	-9306
RPL10L	-9192
LHX2	-9171
RPL13	-9165
PPP3CB	-9019
RPL10A	-8981
RPS13	-8885
PSMA8	-8792
RPL24	-8697
RPS26	-8630
RAC1	-8610

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL29	-10734.0
RPS12	-10480.0
RPS25	-9996.0
MAGOH	-9876.0
RPL12	-9789.0
UBB	-9702.0
RPL23	-9573.0
RPL18	-9396.0
PSMC4	-9362.0
CXCL12	-9306.0
RPL10L	-9192.0
LHX2	-9171.0
RPL13	-9165.0
PPP3CB	-9019.0
RPL10A	-8981.0
RPS13	-8885.0
PSMA8	-8792.0
RPL24	-8697.0
RPS26	-8630.0
RAC1	-8610.0
RPS6	-8578.0
RPL41	-8474.0
RBM8A	-8468.0
ETF1	-8311.0
RPS28	-8280.0
RPL13A	-8267.5
CAP2	-8255.0
RPL14	-8156.0
RPL11	-8150.0
RPL4	-8026.0
RPL7	-8006.0
LHX9	-8002.0
UBC	-7974.0
PSMD12	-7843.0
RPL39L	-7836.0
FAU	-7687.0
PSMB10	-7431.0
PSMC5	-7419.0
RPL34	-7413.0
RPS15A	-7332.0
ELOC	-7318.0
RPL5	-7169.0
LHX3	-7113.0
PSMB4	-7098.0
RPSA	-6914.0
RPL36AL	-6833.5
PSME4	-6754.0
RPL37	-6752.0
RPLP0	-6587.0
LHX4	-6583.0
RPL23A	-6481.0
RPL35A	-6473.0
RPL21	-6325.0
RPL22L1	-6284.0
RPS3A	-6158.0
PSMC2	-6092.0
PSME2	-6084.0
SLIT2	-6063.0
PSMA3	-5986.0
RPL17	-5981.0
PSMB8	-5844.0
RPL27A	-5715.0
RPS24	-5677.0
RPL18A	-5525.0
RNPS1	-5489.0
RPS18	-5357.0
RPL35	-5265.0
NCBP2	-5148.0
RPL8	-5017.0
RPS20	-4837.0
ELOB	-4810.0
NCK1	-4603.0
RPLP2	-4592.0
GSPT1	-4445.0
PSMA5	-4438.0
UBA52	-4361.0
PSMD11	-4325.0
RPL28	-4300.0
PFN1	-4292.0
PSMD5	-4244.0
RPS10	-4220.0
RPS11	-4189.0
CASC3	-4102.0
PSMD9	-3987.0
RPS5	-3903.0
RPL36	-3867.0
AKAP5	-3727.0
PAK1	-3644.0
PRKACB	-3597.0
RPLP1	-3490.0
RPL15	-3478.0
PSMA6	-3425.0
RPS29	-3289.0
EIF4G1	-3228.0
RBX1	-3122.0
ROBO2	-3112.0
PSMC1	-3076.0
RPL19	-3065.0
PSME3	-3024.0
PSMB9	-2972.0
ROBO1	-2938.0
ROBO3	-2930.0
PRKAR2A	-2896.0
CDC42	-2824.0
SOS2	-2743.0
RPL9	-2640.0
RPS16	-2594.0
RPL30	-2386.0
RPS15	-2337.0
RPL6	-2141.0
PSMD1	-2120.0
CLASP2	-1949.0
RPL3	-1846.0
SRGAP1	-1830.0
PSMB5	-1772.0
RPS2	-1664.0
SLIT1	-1546.0
PSMA1	-1545.0
RPS27A	-1544.0
PSMB3	-1361.0
RPL38	-1357.0
RPS8	-1326.0
RPS23	-1205.0
DCC	-1195.0
RPL37A	-1087.0
UPF3A	-824.0
RPS21	-811.0
SLIT3	-772.0
PSME1	-658.0
PABPC1	-486.0
NCBP1	-381.0
RPS9	-121.0
ABL1	-86.0
SEM1	-1.0
RPL32	63.0
UPF2	298.0
PSMD8	315.0
LDB1	472.0
NELL2	580.0
PFN2	613.0
PSMA7	942.0
PAK5	982.0
PSMA2	1059.0
PSMD7	1158.0
ENAH	1198.0
PSMB2	1566.0
CXCR4	1582.0
RHOA	1702.0
RPS7	1873.0
NCK2	1876.0
CUL2	2205.0
MSI1	2338.0
PSMD14	2369.0
CAP1	2748.0
PSMC3	2777.0
ISL1	2851.0
CLASP1	2993.0
RPL26L1	3302.0
PSMD13	3304.0
RPL27	3305.0
SOS1	3385.0
ABL2	3439.0
PSMB7	3558.0
PSMD4	3642.0
PSMD2	3699.0
PRKCA	3721.0
RPL26	3766.0
RPS27L	3876.0
FLRT3	3878.0
PSMA4	4073.0
NRP1	4306.0
RPL7A	4313.0
PRKACA	4352.0
PSMC6	4442.0
PSMD6	4479.0
MAGOHB	4952.0
DAG1	5020.0
PAK6	5036.0
PSMB6	5196.0
PSMF1	5201.0
VASP	5207.0
NTN1	5216.0
ARHGAP39	5340.0
PSMB1	5414.0
PAK2	5575.0
SRGAP3	5588.0
USP33	5663.0
EIF4A3	5714.0
PAK4	6006.0
HOXA2	6767.0
RPL31	7031.0
RPS3	7084.0
RPS27	7437.0
RPL22	7534.0
RPS14	7712.0
RPS19	7721.0
EVL	8119.0
PSMD3	8120.0
GPC1	8651.0
SRC	8731.0
MYO9B	8756.0
SRGAP2	9117.0
ZSWIM8	9560.0
RPL3L	9685.0
PSMB11	9803.0
PRKACG	10288.0

---

REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES

REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES

	615
set	REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES
setSize	55
pANOVA	6.14e-05
s.dist	-0.312
p.adjustANOVA	0.0056

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CCL4	-11038
CCL3	-11017
CCL5	-10864
CXCL3	-10823
CCL19	-10801
CCL2	-10725
CXCL6	-10486
CXCL2	-10475
CCL1	-10207
CXCL10	-9997
CCL7	-9952
CCR10	-9815
CXCL1	-9709
CXCL13	-9705
PPBP	-9638
CCR5	-9411
CCR2	-9318
CXCL12	-9306
ACKR4	-9178
CX3CR1	-9120

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CCL4	-11038
CCL3	-11017
CCL5	-10864
CXCL3	-10823
CCL19	-10801
CCL2	-10725
CXCL6	-10486
CXCL2	-10475
CCL1	-10207
CXCL10	-9997
CCL7	-9952
CCR10	-9815
CXCL1	-9709
CXCL13	-9705
PPBP	-9638
CCR5	-9411
CCR2	-9318
CXCL12	-9306
ACKR4	-9178
CX3CR1	-9120
ACKR2	-8849
CCL21	-8612
CXCR5	-8494
XCL2	-8241
CCR8	-7483
CCL22	-7402
PF4	-6385
CCL28	-6357
CXCL5	-6189
CCR6	-5028
CCL20	-4657
CXCL8	-3658
CCR7	-2917
CXCL16	-2636
CCL11	-2170
CCRL2	-1356
CXCR2	-642
CCL25	46
CCL16	949
CXCR6	1181
CXCR4	1582
CCL13	1975
CXCR1	2708
CCR1	4588
ACKR3	5527
CXCL11	6158
CX3CL1	7051
XCL1	7129
CCR4	7273
XCR1	7482
CXCL9	8425
CCR9	8824
CCL17	8925
CCR3	10780
CCL27	10812

---

REACTOME_CELLULAR_RESPONSES_TO_STIMULI

REACTOME_CELLULAR_RESPONSES_TO_STIMULI

	1314
set	REACTOME_CELLULAR_RESPONSES_TO_STIMULI
setSize	779
pANOVA	9.23e-05
s.dist	-0.0823
p.adjustANOVA	0.00797

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RLN1	-11032
MIR24-2	-10861
CAPZA3	-10798
RPL29	-10734
CCL2	-10725
CDKN2D	-10701
COX14	-10527
MT1M	-10513
RPS12	-10480
H2AC20	-10322
EGLN3	-10309
SOD2	-10290
ATP6V0E2	-10271
PRDX6	-10239
CREB3L4	-10230
MT3	-10198
ERN1	-10175
NUP50	-10150
ID1	-10135
RPS25	-9996

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RLN1	-11032.0
MIR24-2	-10861.0
CAPZA3	-10798.0
RPL29	-10734.0
CCL2	-10725.0
CDKN2D	-10701.0
COX14	-10527.0
MT1M	-10513.0
RPS12	-10480.0
H2AC20	-10322.0
EGLN3	-10309.0
SOD2	-10290.0
ATP6V0E2	-10271.0
PRDX6	-10239.0
CREB3L4	-10230.0
MT3	-10198.0
ERN1	-10175.0
NUP50	-10150.0
ID1	-10135.0
RPS25	-9996.0
CREB3	-9986.0
LIMD1	-9968.0
HSPA1A	-9954.0
RPA2	-9888.0
RPL12	-9789.0
HSPA1B	-9743.0
UBB	-9702.0
TUBB6	-9696.0
NRIP1	-9662.0
H2AX	-9652.0
UBE2C	-9598.0
CCNE2	-9594.0
HBA1	-9577.0
RPL23	-9573.0
HSPA8	-9533.0
CDK4	-9528.0
CASTOR1	-9491.0
CDC16	-9479.0
MAFG	-9462.0
YWHAE	-9457.0
RPL18	-9396.0
H4C8	-9377.0
XBP1	-9375.0
PSMC4	-9362.0
COX8A	-9358.0
ATP6V1B2	-9288.0
GSTA3	-9199.0
RPL10L	-9192.0
ETS2	-9167.0
RPL13	-9165.0
SKP1	-9156.0
DNAJA2	-9124.0
H3-3A	-9072.0
H2BC21	-9064.0
CCNA1	-9044.0
HSBP1	-9033.0
RPL10A	-8981.0
E2F2	-8950.0
PRDX3	-8933.0
H2BC5	-8892.0
SCO2	-8890.0
RPS13	-8885.0
COX18	-8878.0
TUBA3E	-8829.0
IL6	-8816.0
GCLM	-8799.0
PSMA8	-8792.0
HMGA2	-8762.0
TUBA1B	-8749.0
RPL24	-8697.0
MED1	-8676.0
H1-3	-8659.0
RPS26	-8630.0
TUBB4B	-8604.0
RPS6	-8578.0
RRAGC	-8538.0
H1-4	-8501.0
RPL41	-8474.0
H4C3	-8439.0
NUP42	-8372.0
BAG5	-8331.0
NUP153	-8324.0
ATP6V1E1	-8322.0
HMGA1	-8287.0
RPS28	-8280.0
HBB	-8277.0
CALR	-8269.0
RPL13A	-8267.5
PGD	-8234.0
NLRP3	-8233.0
SYVN1	-8178.0
TACO1	-8176.0
RPL14	-8156.0
RPL11	-8150.0
AAAS	-8141.0
PHC1	-8059.0
RPL4	-8026.0
RPL7	-8006.0
COX20	-8004.0
H3C10	-7994.0
UBC	-7974.0
TUBB2A	-7957.0
ITFG2	-7956.0
GPX7	-7918.0
ANAPC10	-7909.0
MAPK10	-7890.0
H2BC11	-7869.0
ERO1A	-7859.0
PSMD12	-7843.0
RPL39L	-7836.0
SHC1	-7816.0
DEDD2	-7785.0
PRDX2	-7751.0
MT1A	-7740.0
MAPK1	-7718.0
EIF2S1	-7708.0
FAU	-7687.0
DNAJA1	-7605.0
H2BC14	-7552.0
COX5A	-7517.0
HDGF	-7471.0
MAP1LC3B	-7452.0
PSMB10	-7431.0
PSMC5	-7419.0
RPL34	-7413.0
DNAJC2	-7359.0
RRAGA	-7337.0
RPS15A	-7332.0
ELOC	-7318.0
ANAPC16	-7276.0
H2BC17	-7263.0
CAPZA2	-7182.0
RPL5	-7169.0
HSPA4L	-7100.0
PSMB4	-7098.0
H2BC4	-7072.0
FKBP14	-7047.0
EXOSC5	-7041.0
SLC46A1	-7014.0
SESN2	-6986.0
H3-3B	-6937.0
RPS6KA1	-6926.0
RPSA	-6914.0
TXNIP	-6880.0
TUBB8	-6855.0
RPL36AL	-6833.5
RAD50	-6818.0
HSP90AB1	-6813.0
H3C2	-6790.0
SRPRA	-6789.0
PSME4	-6754.0
RPL37	-6752.0
ATF4	-6740.0
LMNA	-6732.0
SLC38A9	-6703.0
H2AJ	-6672.0
AGO3	-6613.0
H2BC13	-6590.0
RPLP0	-6587.0
EIF2S2	-6580.0
ATF3	-6537.0
TUBB4A	-6499.0
UBE2D2	-6483.0
RPL23A	-6481.0
RPL35A	-6473.0
NDUFA4	-6467.0
GPX1	-6452.0
MAPKAPK3	-6451.0
H2AC8	-6445.0
COX11	-6434.0
HSPA13	-6383.0
RPL21	-6325.0
NCF2	-6315.0
RPL22L1	-6284.0
MAPK14	-6253.0
H2AC7	-6250.5
H2BC7	-6250.5
IDH1	-6229.0
ST13	-6213.0
EPO	-6201.0
TUBB2B	-6175.0
RPS3A	-6158.0
SCO1	-6146.0
NCOA2	-6134.0
NUP35	-6110.0
H2AC6	-6100.0
PSMC2	-6092.0
PSME2	-6084.0
HSPA5	-6069.0
POM121	-6050.0
FKBP4	-6005.0
HSP90AA1	-6002.0
CDK2	-6001.0
UBE2E1	-5994.0
H2BC8	-5989.0
PSMA3	-5986.0
RPL17	-5981.0
CAPZA1	-5977.0
TUBB3	-5860.0
PSMB8	-5844.0
IGFBP7	-5792.0
CHD9	-5790.0
CCNA2	-5784.0
BACH1	-5763.0
ATP6V1C1	-5753.0
SIN3A	-5724.0
RPL27A	-5715.0
H2AC18	-5704.5
H2AC19	-5704.5
RPS24	-5677.0
LMNB1	-5652.0
ERF	-5624.0
MEF2C	-5570.0
ACTR10	-5559.0
H3C4	-5557.0
RPL18A	-5525.0
EIF2AK3	-5491.0
H2AC14	-5481.0
TNRC6B	-5477.0
NUP205	-5439.0
EXTL2	-5424.0
COX6B1	-5397.0
RPS18	-5357.0
H1-0	-5302.0
RAE1	-5266.0
RPL35	-5265.0
TUBA1C	-5216.0
CCS	-5201.0
FKBP5	-5170.0
WIPI1	-5154.0
MAP3K5	-5112.0
H3C12	-5090.0
DCTN2	-5035.0
RPL8	-5017.0
GPX8	-4990.0
HBA2	-4961.0
RHEB	-4907.0
EGLN1	-4865.0
MT1G	-4855.0
DCP2	-4848.0
RPS20	-4837.0
ELOB	-4810.0
MYDGF	-4760.0
MUL1	-4720.0
NUDT2	-4688.0
NUP37	-4666.0
NUP155	-4621.0
GPX2	-4604.0
RPLP2	-4592.0
PPARGC1A	-4586.0
FNIP2	-4561.0
CDKN2A	-4556.0
COX5B	-4533.0
CDK6	-4485.0
NUP133	-4483.0
TGS1	-4456.0
MDM4	-4448.0
AKT1S1	-4441.0
PSMA5	-4438.0
CUL1	-4436.0
EEF1A1	-4419.0
UBA52	-4361.0
UBXN7	-4337.0
PSMD11	-4325.0
RPL28	-4300.0
PPP2R5B	-4264.0
PSMD5	-4244.0
RBBP4	-4237.0
RPS10	-4220.0
H2BC6	-4207.0
ATP6V1D	-4203.0
RPS11	-4189.0
ATP6V1G1	-4171.0
HSPA2	-4140.0
CREB3L3	-4131.0
DNAJB9	-4125.0
H4C6	-4120.0
CDC26	-4109.0
EXOSC3	-4085.0
ATOX1	-4080.0
PSMD9	-3987.0
BAG4	-3965.0
HSPA14	-3911.0
RPS5	-3903.0
RPL36	-3867.0
TUBA1A	-3854.0
MYC	-3827.0
H3C11	-3817.0
MTF1	-3798.0
UBE2S	-3726.0
EXOSC8	-3710.0
SKP2	-3685.0
HSPB1	-3666.0
CXCL8	-3658.0
SIN3B	-3563.0
ASNS	-3531.0
H1-2	-3506.0
RPLP1	-3490.0
RPL15	-3478.0
CDC23	-3430.0
E2F3	-3426.0
PSMA6	-3425.0
KEAP1	-3390.0
RPS29	-3289.0
EXOSC7	-3252.0
HIF1A	-3234.0
NFKB1	-3211.0
EXOSC1	-3185.0
RNF2	-3178.0
MEF2D	-3171.0
RBX1	-3122.0
HIKESHI	-3111.0
CREB3L1	-3098.0
H4C13	-3097.0
PSMC1	-3076.0
RPL19	-3065.0
PSME3	-3024.0
MAPKAPK5	-3000.0
SOD1	-2982.0
GSK3B	-2980.0
PSMB9	-2972.0
NFE2L2	-2909.0
HSPA1L	-2899.0
UBE2D3	-2867.0
HERPUD1	-2840.0
DYNLL1	-2813.0
DYNC1I2	-2792.0
POM121C	-2759.0
AJUBA	-2740.0
LRPPRC	-2720.0
ARNT	-2718.0
MAP2K3	-2693.0
FABP1	-2648.0
RPL9	-2640.0
MAPKAPK2	-2623.0
CREB1	-2614.0
HSPB8	-2604.0
RPS16	-2594.0
SP1	-2592.0
STAT3	-2557.0
PRDX1	-2515.0
NUP43	-2489.0
RPL30	-2386.0
FNIP1	-2372.0
RPS15	-2337.0
CREBRF	-2314.0
TXN	-2287.0
HSPH1	-2231.0
H2AZ2	-2221.0
ANAPC1	-2192.0
RPL6	-2141.0
PSMD1	-2120.0
MT1X	-2082.0
NCOA6	-2049.0
DYNC1I1	-2041.0
ATP6V1F	-2015.0
KDELR3	-2009.0
KAT5	-1954.0
NDC1	-1937.0
CA9	-1898.0
LAMTOR5	-1886.0
KICS2	-1855.0
RPL3	-1846.0
NOX4	-1843.0
PSMB5	-1772.0
COX19	-1736.0
H1-5	-1713.0
DDIT3	-1681.0
SQSTM1	-1672.0
RPS2	-1664.0
VCP	-1618.0
PRDX5	-1554.0
PSMA1	-1545.0
RPS27A	-1544.0
VHL	-1534.0
CSNK2B	-1533.0
H2AZ1	-1527.0
DNAJB11	-1517.0
TERF2IP	-1493.0
MDM2	-1436.0
BLVRB	-1426.0
PSMB3	-1361.0
RPL38	-1357.0
ATF6	-1344.0
RPS8	-1326.0
ATP6V1A	-1254.0
BMI1	-1236.0
RPS23	-1205.0
H4C2	-1183.0
TP53	-1167.0
ACD	-1164.5
CSRP1	-1155.0
TNFRSF21	-1140.0
NBN	-1104.0
RPL37A	-1087.0
PPP1R15A	-1086.0
RORA	-1030.0
STIP1	-902.0
GRB10	-889.0
RPS21	-811.0
PHC3	-751.0
H4C1	-737.0
CBX4	-694.0
CSNK2A1	-662.0
PSME1	-658.0
ATP6V1H	-645.0
ACADVL	-624.0
CCNE1	-622.0
H4C5	-618.0
AGO4	-531.0
HM13	-518.0
TLR4	-494.0
ATP6V0E1	-419.0
H2BC15	-371.0
CRYAB	-361.0
NR3C1	-354.0
VENTX	-343.0
GOSR2	-335.0
MRE11	-301.0
TUBA4B	-299.0
TATDN2	-257.0
DIS3	-214.0
HIGD1A	-162.0
MT1E	-160.0
TBL1XR1	-134.0
RPS9	-121.0
ETS1	-97.0
H2BC1	-54.0
CTDSP2	-52.0
ATF2	-41.0
MAPK7	-30.0
COX16	-12.0
SEM1	-1.0
BLVRA	39.0
RPL32	63.0
CYBA	64.0
NUP85	69.0
NUP214	74.0
CAMK2D	77.0
ACTR1A	79.0
CUL3	100.0
GML	105.0
TINF2	133.0
HSP90B1	178.0
NFYB	191.0
SRPRB	213.0
DCTN5	251.0
DNAJB6	267.0
PSMD8	315.0
PTK6	345.0
MOV10	387.0
JUN	408.0
KHSRP	419.0
CSNK2A2	438.0
HIF1AN	461.0
KDM6B	476.0
DYNC1LI2	507.0
BMT2	545.0
POT1	557.0
CYCS	595.0
CBX2	599.0
CDKN1A	606.0
PRKCD	639.0
SERP1	651.0
NR1D1	661.0
H2BC12	672.0
APOB	682.0
TUBA3C	701.0
EXTL3	757.0
RAI1	764.0
EP300	781.0
TPP1	785.0
BTRC	810.0
PSMA7	942.0
SOD3	957.0
ANAPC7	1021.0
PSMA2	1059.0
HSPA9	1078.0
MAP2K6	1098.0
SIRT1	1151.0
PSMD7	1158.0
GSTP1	1223.0
DCTN6	1227.0
TNIK	1245.0
ATP6V0D2	1254.0
DYNC1LI1	1261.0
COX6A1	1265.0
IL1A	1307.0
SLC7A11	1321.0
SH3BP4	1333.0
GFPT1	1334.0
KPTN	1361.0
CBX8	1366.0
DNAJC7	1381.0
GPX3	1383.0
TERF2	1386.0
BRCA1	1391.0
IMPACT	1415.0
NUP107	1548.0
PTGES3	1557.0
PSMB2	1566.0
TALDO1	1601.0
DEPDC5	1679.0
GSK3A	1699.0
HELZ2	1738.0
XPO1	1743.0
COX4I1	1790.0
GPX5	1809.0
NOX5	1828.0
HDAC3	1872.0
RPS7	1873.0
NCOR1	1885.0
TUBA8	1901.0
ATP6V0C	1942.0
NR3C2	2006.0
UBN1	2010.0
ASF1A	2017.0
CDKN1B	2040.0
SEH1L	2049.0
EED	2064.0
MT1F	2112.0
ME1	2138.0
HYOU1	2144.0
COX6C	2174.0
CUL2	2205.0
CAMK2G	2220.0
EXOSC9	2285.0
MAP4K4	2290.0
ATP6V1C2	2355.0
PSMD14	2369.0
UFD1	2376.0
HSPA4	2407.0
CDKN2B	2511.0
TRIM21	2664.0
TXNRD1	2669.0
BMAL1	2675.0
RRAGD	2720.0
NUP88	2756.0
PSMC3	2777.0
BAG1	2787.0
EGLN2	2826.0
NUP188	2838.0
PREB	2849.0
NUP160	2878.0
H2AC4	2947.0
CLOCK	2971.0
MAPK11	2972.0
SESN1	2984.0
EDEM1	2987.0
DNAJA4	2997.0
LAMTOR4	3035.0
CAPZB	3073.0
PDIA6	3092.0
PHC2	3102.0
SRXN1	3116.0
EZH2	3126.0
CITED2	3145.0
MT1H	3146.0
SNCB	3147.0
RPA3	3162.0
ATM	3236.0
CEBPG	3251.0
H4C16	3253.0
ANAPC11	3289.0
RPL26L1	3302.0
PSMD13	3304.0
RPL27	3305.0
NPLOC4	3341.0
PGR	3346.0
MAPK8	3348.0
TXN2	3380.0
E2F1	3427.0
RING1	3445.0
ANAPC5	3520.0
SURF1	3528.0
TPR	3550.0
PSMB7	3558.0
HSPB2	3562.0
BAG2	3638.0
PSMD4	3642.0
STAP2	3663.0
PSMD2	3699.0
TNRC6A	3724.0
ATP6V1E2	3746.0
HIF3A	3750.0
IGFBP1	3764.0
RPL26	3766.0
RXRA	3824.0
AKT3	3841.0
WDR59	3844.0
ABCC1	3863.0
RPS27L	3876.0
NUP98	3900.0
HSPA12B	3946.0
KLHDC3	3985.0
ATF5	4048.0
PSMA4	4073.0
GSR	4098.0
DCSTAMP	4108.0
NFYC	4149.0
EIF2AK1	4157.0
NCOA1	4237.0
H3C1	4262.0
NPRL2	4273.0
RPL7A	4313.0
PARN	4336.0
DYNLL2	4409.0
DCTN4	4414.0
PSMC6	4442.0
SMARCD3	4464.0
FZR1	4472.0
PSMD6	4479.0
SSR1	4480.0
ALB	4560.0
RPS6KA2	4563.0
PALB2	4597.0
H2BC26	4643.0
UBE2D1	4660.0
CAMK2A	4700.0
MLST8	4747.0
MAPK9	4786.0
HSPA12A	4837.0
CHAC1	4891.0
NCOR2	4914.0
FOS	4918.0
USP46	4938.0
FBXL17	4941.0
CAT	4947.0
NUP54	4974.0
ANAPC15	5002.0
LAMTOR2	5007.0
APOA1	5027.0
SEC31A	5082.0
ANAPC4	5089.0
RPA1	5108.0
PSMB6	5196.0
PSMF1	5201.0
COX7A2L	5212.0
H4C9	5218.0
ATP6V1G2	5302.0
H2BC9	5307.5
H3C7	5307.5
HIRA	5359.0
TKT	5371.0
CREB3L2	5410.0
PSMB1	5414.0
EIF2AK4	5421.0
MT2A	5459.0
NUP93	5467.0
DPP3	5493.0
TUBA4A	5539.0
CRTC2	5581.0
CLEC1B	5591.0
ADD1	5639.0
HMOX2	5676.0
DNAJC3	5724.0
ATR	5740.0
NUP210	5745.0
NUP58	5846.0
NCF4	5860.0
VEGFA	5881.0
NFYA	5913.0
CRTC3	5918.0
MIOS	5959.0
MIR24-1	6007.0
DCTN3	6020.0
CDC27	6028.0
EXOSC4	6081.0
CEBPB	6090.0
ATP6V1B1	6093.0
NQO1	6163.0
MAPK3	6201.0
WFS1	6233.0
ATP6V1G3	6253.0
EXTL1	6329.0
NPAS2	6349.0
RB1	6425.0
CDKN2C	6469.0
SERPINH1	6482.0
H4C4	6524.0
PPARA	6536.0
DNAJB1	6558.0
HMOX1	6570.0
CBX6	6575.0
H3C6	6602.0
LAMTOR1	6612.0
IFNB1	6637.0
TERF1	6662.0
LAMTOR3	6679.0
CXXC1	6709.0
GCLC	6763.0
YIF1A	6806.0
NOTCH1	6821.0
ARFGAP1	6849.0
GSTA1	6951.0
MRPL18	6968.0
MAP2K4	6996.0
RPL31	7031.0
PDIA5	7038.0
DCTN1	7044.0
RPS3	7084.0
SCMH1	7139.0
TFDP2	7179.0
MAFK	7260.0
GPX6	7300.0
H4C12	7358.0
EPAS1	7371.0
RANBP2	7396.0
TNRC6C	7431.0
RPS27	7437.0
NUP62	7457.0
WTIP	7495.0
GCN1	7532.0
RPL22	7534.0
COX7C	7538.0
TXNRD2	7549.0
RELA	7644.0
EHMT1	7646.0
EP400	7707.0
RPS14	7712.0
RPS19	7721.0
HSPA6	7793.0
AKT1	7830.0
MBTPS1	7837.0
TLN1	7849.0
WDR24	7874.0
EXOSC2	7893.0
ANAPC2	7945.0
ZBTB17	8074.0
ATP6V0B	8105.0
PSMD3	8120.0
CRTC1	8131.0
TUBAL3	8192.0
H2BC3	8253.0
MINK1	8264.0
TUBB1	8278.0
LY96	8281.0
CAMK2B	8374.0
CABIN1	8407.0
MAP2K7	8419.0
SEC13	8482.0
EHMT2	8607.0
MTOR	8691.0
NPRL3	8766.0
BAG3	8795.0
SZT2	8897.0
DDX11	8989.0
DYNC1H1	9026.0
EXOSC6	9038.0
CREBBP	9058.0
H3C3	9119.0
ATP6V0D1	9150.0
AGO1	9230.0
H2BC10	9234.0
RPTOR	9243.0
SUZ12	9312.0
CRYBA4	9348.0
TFDP1	9373.0
RPS19BP1	9481.0
CCAR2	9490.0
AQP8	9506.0
H4C11	9599.0
AKT2	9642.0
H1-1	9653.0
FLCN	9674.0
RPL3L	9685.0
HSF1	9698.0
TCIRG1	9742.0
PSMB11	9803.0
TRIB3	9868.0
CARM1	9874.0
H3C8	9880.0
MT4	9920.0
MT1B	10033.0
TUBA3D	10241.0
H3-4	10284.0
CUL7	10339.0
P4HB	10390.0
PLA2G4B	10822.0

---

REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS

REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS

	601
set	REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS
setSize	188
pANOVA	0.000148
s.dist	-0.16
p.adjustANOVA	0.0122

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CCL4	-11038
CCL3	-11017
AVP	-10970
CCL5	-10864
CXCL3	-10823
CCL19	-10801
CCL2	-10725
NPB	-10697
UTS2	-10549
GALR2	-10505
CXCL6	-10486
CXCL2	-10475
C5AR2	-10415
FPR2	-10404
F2RL1	-10391
RXFP4	-10270
CCL1	-10207
CXCL10	-9997
CCL7	-9952
CCR10	-9815

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CCL4	-11038
CCL3	-11017
AVP	-10970
CCL5	-10864
CXCL3	-10823
CCL19	-10801
CCL2	-10725
NPB	-10697
UTS2	-10549
GALR2	-10505
CXCL6	-10486
CXCL2	-10475
C5AR2	-10415
FPR2	-10404
F2RL1	-10391
RXFP4	-10270
CCL1	-10207
CXCL10	-9997
CCL7	-9952
CCR10	-9815
CXCL1	-9709
CXCL13	-9705
MC3R	-9660
PPBP	-9638
NMBR	-9545
RLN3	-9473
CCR5	-9411
CCR2	-9318
CXCL12	-9306
ACKR4	-9178
CX3CR1	-9120
F2RL3	-9107
MCHR2	-8992
QRFPR	-8954
PYY	-8873
ACKR2	-8849
CCL21	-8612
AVPR1B	-8596
GRP	-8526
CXCR5	-8494
RXFP1	-8325
RLN2	-8285
SSTR2	-8276
XCL2	-8241
TRH	-8073
EDNRB	-8017
NPY1R	-7982
NPY5R	-7691
SSTR1	-7674
ANXA1	-7584
SAA1	-7546
AGTR1	-7494
CCR8	-7483
CCL22	-7402
AGT	-7317
NPY2R	-7307
EDN1	-7192
EDN2	-7189
SSTR5	-6991
MC1R	-6450
PF4	-6385
CCL28	-6357
NPSR1	-6327
CXCL5	-6189
NPBWR1	-5756
OPRK1	-5744
NTSR1	-5544
NMUR1	-5364
AVPR1A	-5272
QRFP	-5243
TRHR	-5207
OPRL1	-5140
HEBP1	-5082
CCR6	-5028
PNOC	-4956
NMU	-4921
KISS1R	-4828
PRLHR	-4718
CCL20	-4657
NPW	-4581
UTS2B	-4531
POMC	-4416
OXTR	-4363
FPR3	-4286
CXCL8	-3658
NMS	-3617
ACKR1	-3344
EDN3	-3293
HCRTR2	-3205
GPR37	-3163
APP	-3117
GHRL	-3030
CCR7	-2917
NPFFR2	-2849
CCK	-2752
BDKRB1	-2651
RXFP2	-2643
CXCL16	-2636
PDYN	-2553
GHSR	-2507
MLNR	-2298
CCL11	-2170
UTS2R	-2024
F2RL2	-2020
TACR3	-2008
NPY	-1832
FPR1	-1811
PSAP	-1802
MC2R	-1657
F2R	-1585
ECE2	-1562
INSL5	-1390
CCRL2	-1356
OXT	-1233
C5AR1	-817
CCL23	-807
PROK2	-784
CXCR2	-642
C3AR1	-468
CCL25	46
KEL	95
GAL	245
TAC1	944
CCL16	949
CXCR6	1181
CCKBR	1400
CXCR4	1582
GALR1	1629
CCL13	1975
CXCR1	2708
SST	2745
NLN	2780
C5	2820
EDNRA	3056
OPRM1	3059
TACR1	3156
NPFFR1	3371
C3	3375
BDKRB2	3635
PROKR1	3733
NPS	3763
CCR1	4588
NTS	4753
RXFP3	4943
NMUR2	4948
MCHR1	4966
KNG1	5071
GPER1	5301
APLNR	5366
ACKR3	5527
OPRD1	6077
CXCL11	6158
CORT	6297
F2	6639
SSTR4	6902
ECE1	6995
CX3CL1	7051
XCL1	7129
NPBWR2	7228
PENK	7248
CCR4	7273
MLN	7304
PROK1	7324
XCR1	7482
PMCH	7514
MC5R	7580
NTSR2	7733
NMB	7918
TACR2	7965
CCKAR	8144
CXCL9	8425
GALR3	8437
PROKR2	8520
TAC3	8639
GPR37L1	8744
CCR9	8824
CCL17	8925
INSL3	8940
KISS1	9344
HCRTR1	9369
PRLH	10082
MC4R	10087
NPFF	10156
SSTR3	10217
HCRT	10265
PPY	10609
CCR3	10780
CCL27	10812

---

REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT

REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT

	77
set	REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT
setSize	58
pANOVA	0.000238
s.dist	-0.279
p.adjustANOVA	0.0186

Top enriched genes

Top 20 genes

GeneID	Gene Rank
NDUFB8	-10189
PAM16	-10091
MTX1	-9715
GRPEL2	-9643
ATP5F1B	-9402
LDHD	-9232
CHCHD4	-9213
CHCHD2	-9169
ATP5F1A	-8779
CHCHD10	-8535
GRPEL1	-8361
CS	-8221
COA4	-8079
TOMM70	-8001
MTX2	-7258
TIMM10B	-6626
CMC2	-6564
TIMM9	-6560
SLC25A12	-6367
COQ2	-6252

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
NDUFB8	-10189
PAM16	-10091
MTX1	-9715
GRPEL2	-9643
ATP5F1B	-9402
LDHD	-9232
CHCHD4	-9213
CHCHD2	-9169
ATP5F1A	-8779
CHCHD10	-8535
GRPEL1	-8361
CS	-8221
COA4	-8079
TOMM70	-8001
MTX2	-7258
TIMM10B	-6626
CMC2	-6564
TIMM9	-6560
SLC25A12	-6367
COQ2	-6252
TIMM10	-5650
TIMM13	-5625
TOMM6	-5516
HSPD1	-5428
CYC1	-5287
TIMM21	-5079
TIMM23	-4976
TOMM22	-4721
TOMM5	-3950
DNAJC19	-3562
CHCHD3	-3459
FXN	-3454
ATP5MC1	-3204
TIMM8B	-2831
TIMM50	-1983
COX19	-1736
CHCHD7	-1362
BCS1L	-1307
TOMM20	-1034
SLC25A13	-909
TIMM17A	-568
SAMM50	-272
VDAC1	192
SLC25A4	457
HSCB	684
COA6	745
TOMM40	896
HSPA9	1078
TOMM7	1586
GFER	2237
COX17	2903
TIMM22	4216
CHCHD5	5404
PMPCB	5761
PITRM1	6185
ACO2	7889
PMPCA	8569
TIMM44	9004

---

REACTOME_NERVOUS_SYSTEM_DEVELOPMENT

REACTOME_NERVOUS_SYSTEM_DEVELOPMENT

	1536
set	REACTOME_NERVOUS_SYSTEM_DEVELOPMENT
setSize	552
pANOVA	0.00103
s.dist	-0.0817
p.adjustANOVA	0.07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TYROBP	-11000
RPL29	-10734
RPS12	-10480
ACTB	-10373
SCN11A	-10154
POU3F2	-10115
RPS25	-9996
RRAS	-9930
MAGOH	-9876
CLTA	-9790
RPL12	-9789
TREM2	-9736
UBB	-9702
TUBB6	-9696
PTPN11	-9664
RPL23	-9573
CNTN6	-9568
HSPA8	-9533
PIK3R2	-9426
RPL18	-9396

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TYROBP	-11000.0
RPL29	-10734.0
RPS12	-10480.0
ACTB	-10373.0
SCN11A	-10154.0
POU3F2	-10115.0
RPS25	-9996.0
RRAS	-9930.0
MAGOH	-9876.0
CLTA	-9790.0
RPL12	-9789.0
TREM2	-9736.0
UBB	-9702.0
TUBB6	-9696.0
PTPN11	-9664.0
RPL23	-9573.0
CNTN6	-9568.0
HSPA8	-9533.0
PIK3R2	-9426.0
RPL18	-9396.0
CD72	-9372.0
PSMC4	-9362.0
CXCL12	-9306.0
GFRA3	-9291.0
EFNA4	-9282.0
EFNA2	-9254.0
NRAS	-9202.0
RPL10L	-9192.0
LHX2	-9171.0
RPL13	-9165.0
COL4A4	-9050.0
APH1B	-9040.0
PPP3CB	-9019.0
RPL10A	-8981.0
DOK5	-8899.0
RPS13	-8885.0
TUBA3E	-8829.0
PSMA8	-8792.0
TUBA1B	-8749.0
YAP1	-8707.0
RPL24	-8697.0
RPS26	-8630.0
RAC1	-8610.0
TUBB4B	-8604.0
RPS6	-8578.0
EFNB3	-8552.0
RPL41	-8474.0
RBM8A	-8468.0
CHL1	-8444.0
SDC2	-8430.0
ETF1	-8311.0
RPS28	-8280.0
RPL13A	-8267.5
CAP2	-8255.0
RPL14	-8156.0
RPL11	-8150.0
UNC5C	-8086.0
RPL4	-8026.0
RPL7	-8006.0
LHX9	-8002.0
UBC	-7974.0
TUBB2A	-7957.0
SCN2A	-7876.0
PSMD12	-7843.0
RPL39L	-7836.0
SHC1	-7816.0
EFNA1	-7769.0
COL4A3	-7747.0
SCN8A	-7731.0
MAPK1	-7718.0
ACTG1	-7705.0
FAU	-7687.0
ADGRV1	-7616.0
ST8SIA4	-7583.0
EPHA7	-7498.0
PSMB10	-7431.0
PSMC5	-7419.0
RPL34	-7413.0
RPS15A	-7332.0
ELOC	-7318.0
LYN	-7312.0
VLDLR	-7252.0
SCN1A	-7193.0
RPL5	-7169.0
CNTN1	-7155.0
GDNF	-7136.0
LHX3	-7113.0
PSMB4	-7098.0
ST8SIA2	-7092.0
YES1	-6977.0
RPS6KA1	-6926.0
RPSA	-6914.0
TUBB8	-6855.0
MYL12A	-6848.0
MYL12B	-6845.0
RPL36AL	-6833.5
HSP90AB1	-6813.0
COL6A5	-6792.0
PSME4	-6754.0
RPL37	-6752.0
ITGA9	-6725.0
COL5A3	-6711.0
EPHA3	-6659.0
RPLP0	-6587.0
LHX4	-6583.0
KCNQ3	-6579.0
HDAC2	-6547.0
SEMA6D	-6505.0
TUBB4A	-6499.0
RPL23A	-6481.0
RPL35A	-6473.0
GAB1	-6416.0
COL9A1	-6330.0
RPL21	-6325.0
HMGCR	-6306.0
HJV	-6292.0
RPL22L1	-6284.0
MAPK14	-6253.0
ITGA5	-6235.0
GAB2	-6223.0
TUBB2B	-6175.0
RPS3A	-6158.0
LIMK1	-6124.0
DAB1	-6123.0
PSMC2	-6092.0
PSME2	-6084.0
SLIT2	-6063.0
ADGRG6	-6038.0
PTPRC	-6035.0
HSP90AA1	-6002.0
PSMA3	-5986.0
RPL17	-5981.0
SCN3B	-5944.0
NTN4	-5928.0
SH3GL2	-5875.0
TUBB3	-5860.0
SEMA3E	-5856.0
PSMB8	-5844.0
EPHA10	-5840.0
EFNB2	-5791.0
PIK3R1	-5752.0
RPL27A	-5715.0
RPS24	-5677.0
SCN4B	-5658.0
DOK2	-5632.0
ABLIM3	-5595.0
FES	-5574.0
DPYSL4	-5549.0
RPL18A	-5525.0
GRIN1	-5515.0
RNPS1	-5489.0
MET	-5427.0
EFNA5	-5421.0
SCN1B	-5390.0
RPS18	-5357.0
RPL35	-5265.0
TUBA1C	-5216.0
CACNB2	-5197.0
NCBP2	-5148.0
NRP2	-5131.0
FYN	-5019.0
RPL8	-5017.0
APH1A	-4917.0
ACTR2	-4881.0
RPS20	-4837.0
DNM3	-4834.0
ELOB	-4810.0
EPHA5	-4694.0
COL9A3	-4628.0
PSEN2	-4610.0
NCK1	-4603.0
RPS6KA5	-4598.0
RPLP2	-4592.0
CLTC	-4494.0
GSPT1	-4445.0
PSMA5	-4438.0
TRPC4	-4429.0
RELN	-4399.0
UBA52	-4361.0
PSMD11	-4325.0
UNC5D	-4324.0
UTRN	-4302.0
RPL28	-4300.0
PFN1	-4292.0
PSMD5	-4244.0
RPS10	-4220.0
WASL	-4194.0
RPS11	-4189.0
CASC3	-4102.0
SDCBP	-4069.0
SCN3A	-4056.0
ARHGEF12	-4025.0
AP2B1	-4018.0
EZR	-4015.0
ARPC5	-4011.0
PSMD9	-3987.0
NEO1	-3910.0
RPS5	-3903.0
RPL36	-3867.0
TUBA1A	-3854.0
RHOC	-3818.0
AKAP5	-3727.0
GRB7	-3707.0
PAK1	-3644.0
LAMB1	-3602.0
PRKACB	-3597.0
RPLP1	-3490.0
DOK6	-3481.0
RPL15	-3478.0
KALRN	-3477.0
PSMA6	-3425.0
EGR2	-3304.0
RPS29	-3289.0
EIF4G1	-3228.0
PIK3R3	-3209.0
SEMA4A	-3141.0
RBX1	-3122.0
ROBO2	-3112.0
LAMC1	-3091.0
PSMC1	-3076.0
RPL19	-3065.0
PSME3	-3024.0
SCN9A	-3023.0
CACNB4	-3022.0
GRB2	-2984.0
GSK3B	-2980.0
PSMB9	-2972.0
ROBO1	-2938.0
VAV3	-2932.0
ROBO3	-2930.0
RASA1	-2923.0
SEMA5A	-2908.0
PRKAR2A	-2896.0
CRMP1	-2890.0
DPYSL5	-2834.0
CDC42	-2824.0
SOS2	-2743.0
PMP22	-2723.0
MYO10	-2716.0
ARPC4	-2710.0
NCAN	-2678.0
LYPLA2	-2656.0
EPHB1	-2646.0
RPL9	-2640.0
EGFR	-2625.0
CREB1	-2614.0
CACNB3	-2599.0
RPS16	-2594.0
PRKCQ	-2494.0
NAB1	-2466.0
NCSTN	-2437.0
RPL30	-2386.0
RPS15	-2337.0
SCN2B	-2274.0
RGMB	-2241.0
ANK2	-2235.0
ALCAM	-2220.0
RPL6	-2141.0
PSMD1	-2120.0
DSCAM	-2107.0
TIAM1	-2035.0
PSENEN	-1995.0
CLASP2	-1949.0
TRPC6	-1930.0
MAPK13	-1892.0
RPL3	-1846.0
SRGAP1	-1830.0
LIMK2	-1821.0
PSMB5	-1772.0
SHTN1	-1767.0
RPS2	-1664.0
ABLIM1	-1639.0
SLIT1	-1546.0
PSMA1	-1545.0
RPS27A	-1544.0
CSNK2B	-1533.0
MMP9	-1485.0
LAMA2	-1404.0
KRAS	-1382.0
PSMB3	-1361.0
RPL38	-1357.0
RPS8	-1326.0
PSEN1	-1262.0
SPTBN1	-1240.0
GFRA1	-1237.0
RPS23	-1205.0
DCC	-1195.0
ROCK2	-1173.0
RPL37A	-1087.0
GRIN2B	-1066.0
MBP	-1042.0
ROCK1	-1011.0
GRB10	-889.0
UPF3A	-824.0
RPS21	-811.0
SLIT3	-772.0
CFL1	-741.0
RAP1GAP	-721.0
PIK3CA	-717.0
ARPC2	-698.0
DLG4	-682.0
CSNK2A1	-662.0
PSME1	-658.0
PLXNC1	-648.0
UNC5A	-614.0
SPTBN4	-588.0
PTPRA	-532.0
SEMA3A	-503.0
PABPC1	-486.0
ARHGEF28	-408.0
GFRA4	-403.0
DNM1	-402.0
COL2A1	-389.0
NCBP1	-381.0
CNTNAP1	-376.0
ARHGAP35	-310.0
TUBA4B	-299.0
RANBP9	-244.0
RPS9	-121.0
ITGB1	-101.0
ABL1	-86.0
MAPK7	-30.0
KCNQ2	-18.0
EPHA1	-11.0
SEM1	-1.0
SHC3	13.0
RPL32	63.0
CACNA1C	156.0
PRX	198.0
ITGB3	248.0
UPF2	298.0
PSMD8	315.0
MAP2K1	378.0
ITGA1	433.0
CSNK2A2	438.0
LDB1	472.0
EFNA3	511.0
NELL2	580.0
PFN2	613.0
MYL6	657.0
TUBA3C	701.0
MPZ	706.0
TEAD1	707.0
RDX	724.0
MAPK12	754.0
SIAH1	854.0
DOCK1	898.0
PSMA7	942.0
EPHA2	973.0
PAK5	982.0
PSMA2	1059.0
NRCAM	1131.0
PSMD7	1158.0
ARTN	1164.0
ENAH	1198.0
ITGA10	1216.0
ADAM10	1278.0
TRPC1	1315.0
DPYSL3	1419.0
PLXNA4	1456.0
ARPC3	1491.0
PSMB2	1566.0
CXCR4	1582.0
ARPC1A	1584.0
EPHA6	1593.0
RHOA	1702.0
CDK5	1717.0
LAMA1	1758.0
PTK2	1793.0
RPS7	1873.0
NCK2	1876.0
TUBA8	1901.0
DNM2	2057.0
NAB2	2118.0
RET	2149.0
PIK3CD	2150.0
ERBB2	2158.0
FGFR1	2177.0
CUL2	2205.0
GAP43	2223.0
MMP2	2239.0
MSI1	2338.0
PSMD14	2369.0
SEMA7A	2429.0
COL4A1	2436.0
CACNA1H	2700.0
CAP1	2748.0
SCN7A	2762.0
PSMC3	2777.0
CACNA1G	2790.0
ISL1	2851.0
ITGA2B	2935.0
MAPK11	2972.0
CLASP1	2993.0
GIT1	3020.0
COL5A2	3027.0
AGRN	3030.0
DOK1	3075.0
TRPC3	3155.0
SPTA1	3161.0
WWTR1	3261.0
EPHA4	3294.0
RPL26L1	3302.0
PSMD13	3304.0
RPL27	3305.0
MAPK8	3348.0
CACNA1D	3364.0
ACTR3	3379.0
SOS1	3385.0
ABL2	3439.0
PSMB7	3558.0
PSMD4	3642.0
PSMD2	3699.0
PRKCA	3721.0
RPL26	3766.0
NGEF	3829.0
SIAH2	3855.0
RPS27L	3876.0
FLRT3	3878.0
UNC5B	4015.0
DPYSL2	4018.0
PSMA4	4073.0
SCD5	4248.0
NRP1	4306.0
RPL7A	4313.0
EPHA8	4341.0
PRKACA	4352.0
MYH10	4427.0
PSMC6	4442.0
POU3F1	4446.0
COL4A2	4461.0
PSMD6	4479.0
RPS6KA2	4563.0
ITGA2	4645.0
IRS2	4801.0
DLG1	4811.0
NUMB	4827.0
MYL9	4904.0
PITPNA	4905.0
COL6A6	4931.0
MAGOHB	4952.0
AP2A2	4969.0
DAG1	5020.0
MYH14	5025.0
PAK6	5036.0
CACNA1I	5118.0
CLTCL1	5141.0
ANK3	5172.0
CYP51A1	5181.0
PSMB6	5196.0
PSMF1	5201.0
VASP	5207.0
NTN1	5216.0
ABLIM2	5225.0
ARHGAP39	5340.0
PSMB1	5414.0
ARPC1B	5423.0
PLXND1	5447.0
ARHGEF7	5458.0
MYH9	5470.0
TUBA4A	5539.0
PAK2	5575.0
SRGAP3	5588.0
USP33	5663.0
EIF4A3	5714.0
FARP2	5848.0
PSPN	5962.0
ANK1	5975.0
PAK4	6006.0
ITSN1	6019.0
DSCAML1	6021.0
RGMA	6026.0
FRS2	6075.0
AGAP2	6095.0
AP2A1	6097.0
CDK5R1	6149.0
MAPK3	6201.0
SPTB	6215.0
KIF4B	6289.0
ITGAV	6399.0
COL9A2	6463.0
MAP2K2	6502.0
COL6A1	6522.0
TRIO	6556.0
GFRA2	6627.0
TRPC7	6648.0
HOXA2	6767.0
DOK4	6840.0
EPHB4	6858.0
SPTBN2	6875.0
PIK3CB	6910.0
COL3A1	6950.0
EPHB2	6974.0
RPL31	7031.0
RPS3	7084.0
SEMA6A	7135.0
PLXNA2	7142.0
CACNB1	7202.0
NFASC	7207.0
MYH11	7229.0
NCAM1	7268.0
COL6A3	7272.0
CNTN2	7306.0
ARHGEF11	7334.0
SREBF2	7351.0
PLXNB1	7389.0
RPS27	7437.0
RPL22	7534.0
SEMA4D	7643.0
RPS6KA4	7676.0
RPS14	7712.0
RPS19	7721.0
AP2M1	7773.0
TLN1	7849.0
AP2S1	8082.0
EVL	8119.0
PSMD3	8120.0
TUBAL3	8192.0
SPTAN1	8195.0
TUBB1	8278.0
PRNP	8403.0
HRAS	8450.0
EPHB3	8508.0
PDLIM7	8546.0
GPC1	8651.0
SRC	8731.0
MYO9B	8756.0
PIP5K1C	8846.0
MAG	8893.0
PLCG1	9033.0
EPHB6	9040.0
RHOB	9102.0
SRGAP2	9117.0
COL5A1	9262.0
RND1	9278.0
SMARCA4	9287.0
ZSWIM8	9560.0
RPL3L	9685.0
SCN5A	9760.0
PSMB11	9803.0
SCN10A	9862.0
CLTB	9932.0
VAV2	10056.0
SCN4A	10068.0
COL6A2	10093.0
SPTBN5	10197.0
TUBA3D	10241.0
PRKACG	10288.0
PLXNA1	10442.0
CACNA1S	10444.0
SOX10	10597.0
NRTN	10645.0

---

REACTOME_SARS_COV_1_HOST_INTERACTIONS

REACTOME_SARS_COV_1_HOST_INTERACTIONS

	1550
set	REACTOME_SARS_COV_1_HOST_INTERACTIONS
setSize	92
pANOVA	0.00107
s.dist	-0.197
p.adjustANOVA	0.07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PYCARD	-10974
RPS12	-10480
BST2	-10179
RPS25	-9996
UBB	-9702
STING1	-9618
YWHAE	-9457
TBK1	-9043
NFKBIA	-8939
RPS13	-8885
RPS26	-8630
RPS6	-8578
HNRNPA1	-8516
RPS28	-8280
NLRP3	-8233
TOMM70	-8001
UBC	-7974
FAU	-7687
RPS15A	-7332
IRAK2	-7144

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PYCARD	-10974
RPS12	-10480
BST2	-10179
RPS25	-9996
UBB	-9702
STING1	-9618
YWHAE	-9457
TBK1	-9043
NFKBIA	-8939
RPS13	-8885
RPS26	-8630
RPS6	-8578
HNRNPA1	-8516
RPS28	-8280
NLRP3	-8233
TOMM70	-8001
UBC	-7974
FAU	-7687
RPS15A	-7332
IRAK2	-7144
YWHAH	-6931
RPSA	-6914
IFIH1	-6817
NPM1	-6785
YWHAZ	-6541
RPS3A	-6158
SMAD4	-6076
KPNA2	-5929
KPNB1	-5688
RPS24	-5677
RPS18	-5357
PPIB	-5230
NMI	-4937
YWHAQ	-4922
RPS20	-4837
SMAD3	-4614
EEF1A1	-4419
UBA52	-4361
RPS10	-4220
RPS11	-4189
CASP1	-4103
PCBP2	-4088
RPS5	-3903
RUNX1	-3889
BCL2L1	-3491
RPS29	-3289
NFKB1	-3211
PALS1	-2731
PPIH	-2611
RPS16	-2594
SP1	-2592
RPS15	-2337
SIKE1	-2034
MAVS	-1768
RPS2	-1664
YWHAG	-1652
RPS27A	-1544
CAV1	-1489
PPIG	-1334
RPS8	-1326
RPS23	-1205
FKBP1A	-1001
TRIM25	-816
RPS21	-811
RIPK3	-810
YWHAB	-355
TRAF6	-191
RPS9	-121
IRF3	23
EP300	781
RPS7	1873
UBE2I	2333
IKBKE	3105
RIGI	3277
RPS27L	3876
ITCH	3965
TRAF3	4031
PSMC6	4442
PPIA	5114
RPS3	7084
TKFC	7102
RPS27	7437
RELA	7644
RPS14	7712
RPS19	7721
RCAN3	7865
PDPK1	8583
SERPINE1	8901
SFN	8990
RIPK1	9165
SFTPD	10196
PKLR	10533

---

REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

	116
set	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION
setSize	291
pANOVA	0.00112
s.dist	0.111
p.adjustANOVA	0.07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CTRB2	10603
P4HB	10390
LAMA5	10157
COL6A2	10093
CAPN15	10045
LTBP2	10021
TGFB3	9992
ITGB4	9977
MATN1	9776
BMP1	9750
CEACAM1	9732
COL27A1	9666
CMA1	9592
SCUBE1	9554
PRSS1	9518
EMILIN1	9474
SDC4	9285
COL5A1	9262
ACTN1	9198
MMP19	9141

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CTRB2	10603
P4HB	10390
LAMA5	10157
COL6A2	10093
CAPN15	10045
LTBP2	10021
TGFB3	9992
ITGB4	9977
MATN1	9776
BMP1	9750
CEACAM1	9732
COL27A1	9666
CMA1	9592
SCUBE1	9554
PRSS1	9518
EMILIN1	9474
SDC4	9285
COL5A1	9262
ACTN1	9198
MMP19	9141
COLGALT1	9121
CAPNS2	9034
A2M	9020
PCOLCE	9016
PTPRS	8951
LAMC3	8916
ADAMTS4	8913
SERPINE1	8901
P3H3	8832
KLK2	8732
CTRB1	8575
CTSS	8394
LAMB2	8324
COL10A1	8239
MMP24	8212
CTSB	8142
MMP25	8051
PHYKPL	8044
CD151	7990
SH3PXD2A	7811
CAPN10	7704
ITGB7	7679
CAPN5	7677
COL13A1	7623
CAPN13	7448
MMP15	7430
ASPN	7370
VTN	7308
FBN3	7293
COL6A3	7272
NCAM1	7268
LOXL1	7180
DDR1	7118
CAPN11	7101
COL3A1	6950
COL11A2	6918
CAPN14	6856
DDR2	6735
COL7A1	6704
COL17A1	6678
LAMA3	6649
MMP14	6621
ITGA11	6611
PXDN	6547
COL6A1	6522
ITGAE	6486
SERPINH1	6482
FBLN1	6470
COL9A2	6463
ITGAD	6449
ITGAV	6399
OPTC	6376
FBLN2	6278
TNXB	6195
TMPRSS6	6036
HSPG2	6016
ADAMTS14	6010
CEACAM8	5558
ADAMTS2	5530
FGF2	5483
LOXL3	5477
CAPNS1	5451
PLOD1	5391
COL8A2	5294
MMP20	5200
P3H1	5195
LAMC2	5138
MMP7	5084
CAPN9	5067
EFEMP2	5058
COL18A1	5041
DAG1	5020
ITGA7	4956
COL6A6	4931
SDC1	4882
BSG	4849
EMILIN3	4840
ADAM8	4779
FBLN5	4760
MATN4	4721
ICAM3	4713
CAPN3	4688
ITGA2	4645
THBS1	4615
ACAN	4592
MMP17	4528
P4HA2	4476
COL4A2	4461
VCAM1	4365
COL23A1	4342
LTBP4	4340
P4HA3	4319
COL16A1	4080
TTR	3955
ITGAX	3938
TGFB1	3769
PRKCA	3721
LTBP3	3662
CTSK	3556
LOXL4	3512
GDF5	3472
JAM3	3373
FN1	3290
ITGAL	3181
MMP1	3150
COL1A1	3142
CAPN8	3135
PLOD3	3132
AGRN	3030
COL5A2	3027
ITGA2B	2935
PLEC	2917
COL15A1	2882
IBSP	2860
ITGB2	2817
LOXL2	2750
PDGFA	2732
ITGB5	2713
COL11A1	2529
COL4A1	2436
CAPN7	2342
TNC	2339
MMP2	2239
FBN1	2229
COL22A1	2200
ITGA6	2165
COL26A1	2154
COL1A2	2152
COLGALT2	2114
CAPN2	2028
FGG	2001
TNN	1999
CRTAP	1956
MMP10	1778
LAMA1	1758
CAPN1	1356
DMP1	1348
ADAM10	1278
COL20A1	1231
ITGA10	1216
FGB	1189
KLK7	1081
ITGAM	1055
ITGA4	980
COL21A1	962
DCN	832
ITGA1	433
ITGB6	401
ITGB3	248
ELN	225
CAST	115
PECAM1	82
EFEMP1	43
ITGA8	-3
ITGB1	-101
FBN2	-109
BMP7	-237
LAMB3	-250
ADAMTS16	-351
COL2A1	-389
LAMA4	-451
NRXN1	-551
MFAP2	-583
CASP3	-699
ADAM15	-835
COL28A1	-881
MATN3	-966
ADAMTS8	-1029
COL24A1	-1114
PSEN1	-1262
ADAM12	-1342
LAMA2	-1404
CD47	-1418
MMP9	-1485
MMP8	-1704
CD44	-1715
F11R	-1856
EMILIN2	-1955
TLL2	-2153
TNR	-2219
TIMP2	-2222
VCAN	-2294
SPOCK3	-2312
VWF	-2315
NCSTN	-2437
COL19A1	-2459
P4HA1	-2498
COL8A1	-2602
ITGA3	-2667
NCAN	-2678
P3H2	-2953
LAMC1	-3091
MUSK	-3096
DST	-3116
APP	-3117
LTBP1	-3123
ADAM19	-3435
MMP3	-3522
LAMB1	-3602
SCUBE3	-3858
ADAM9	-4050
MFAP5	-4137
HTRA1	-4151
CTSV	-4312
BMP4	-4389
COL14A1	-4480
TGFB2	-4493
TLL1	-4553
COL9A3	-4628
NID2	-4709
ADAM17	-4731
ADAMTS9	-4830
NID1	-4840
ADAMTS3	-4982
FGA	-4994
BCAN	-5004
LRP4	-5163
PCOLCE2	-5209
KDR	-5228
PPIB	-5230
COL25A1	-5233
MMP13	-5242
ADAMTS5	-5622
FMOD	-5673
ITGB8	-5719
NTN4	-5928
ICAM5	-5961
MFAP3	-6006
MMP11	-6228
ITGA5	-6235
JAM2	-6309
COL9A1	-6330
COL5A3	-6711
ITGA9	-6725
COL6A5	-6792
ADAMTS18	-7152
FURIN	-7294
HAPLN1	-7319
COL12A1	-7347
SDC3	-7400
DSPP	-7453
ICAM1	-7671
KLKB1	-7679
ELANE	-7685
COL4A3	-7747
MFAP4	-7792
MMP12	-7971
MMP16	-8208
ICAM2	-8211
SDC2	-8430
ADAMTS1	-8751
BMP2	-8987
ICAM4	-9013
COL4A4	-9050
CDH1	-9135
COMP	-9353
SPP1	-9354
CAPN12	-9512
TRAPPC4	-9645
PDGFB	-9654
CTSD	-9665
PLOD2	-9802
LOX	-9857
SPARC	-10058
CTSL	-10181
LUM	-10279
BMP10	-10370
MADCAM1	-10519
CEACAM6	-10557
CTSG	-10743
PLG	-10779

---

REACTOME_CALCITONIN_LIKE_LIGAND_RECEPTORS

REACTOME_CALCITONIN_LIKE_LIGAND_RECEPTORS

	717
set	REACTOME_CALCITONIN_LIKE_LIGAND_RECEPTORS
setSize	10
pANOVA	0.00112
s.dist	-0.595
p.adjustANOVA	0.07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CALCA	-10616
CALCB	-9339
ADM2	-9042
ADM	-8245
IAPP	-7230
CALCR	-7180
CALCRL	-5545
RAMP1	-4362
RAMP2	-3492
RAMP3	-858

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CALCA	-10616
CALCB	-9339
ADM2	-9042
ADM	-8245
IAPP	-7230
CALCR	-7180
CALCRL	-5545
RAMP1	-4362
RAMP2	-3492
RAMP3	-858

---

REACTOME_TNFR2_NON_CANONICAL_NF_KB_PATHWAY

REACTOME_TNFR2_NON_CANONICAL_NF_KB_PATHWAY

	978
set	REACTOME_TNFR2_NON_CANONICAL_NF_KB_PATHWAY
setSize	96
pANOVA	0.00115
s.dist	-0.192
p.adjustANOVA	0.07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TNFSF14	-10905
FASLG	-10891
TNFSF4	-10183
TNFRSF6B	-10146
UBA3	-10057
TNF	-9974
UBE2M	-9955
UBB	-9702
TNFRSF17	-9609
TNFRSF12A	-9452
PSMC4	-9362
TNFSF13B	-9265
TNFRSF9	-9263
SKP1	-9156
TNFRSF11A	-9032
TNFSF12	-8863
PSMA8	-8792
CD70	-8737
LTBR	-8690
EDARADD	-8548

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TNFSF14	-10905
FASLG	-10891
TNFSF4	-10183
TNFRSF6B	-10146
UBA3	-10057
TNF	-9974
UBE2M	-9955
UBB	-9702
TNFRSF17	-9609
TNFRSF12A	-9452
PSMC4	-9362
TNFSF13B	-9265
TNFRSF9	-9263
SKP1	-9156
TNFRSF11A	-9032
TNFSF12	-8863
PSMA8	-8792
CD70	-8737
LTBR	-8690
EDARADD	-8548
TNFRSF11B	-8099
UBC	-7974
PSMD12	-7843
TNFRSF1A	-7650
PSMB10	-7431
PSMC5	-7419
PSMB4	-7098
PSME4	-6754
PSMC2	-6092
LTA	-6090
PSME2	-6084
PSMA3	-5986
PSMB8	-5844
FBXW11	-5451
TNFSF8	-4863
PSMA5	-4438
CUL1	-4436
UBA52	-4361
PSMD11	-4325
PSMD5	-4244
BIRC3	-4172
PSMD9	-3987
PSMA6	-3425
TNFRSF13C	-3364
PSMC1	-3076
PSME3	-3024
PSMB9	-2972
TNFSF9	-2962
TNFSF15	-2180
PSMD1	-2120
BIRC2	-1940
PSMB5	-1772
PSMA1	-1545
RPS27A	-1544
PSMB3	-1361
LTB	-1174
PSME1	-658
SEM1	-1
NFKB2	109
PSMD8	315
BTRC	810
PSMA7	942
CD27	989
PSMA2	1059
PSMD7	1158
PSMB2	1566
TNFSF13	1598
MAP3K14	2022
TNFRSF18	2234
PSMD14	2369
TRAF2	2552
TNFRSF25	2736
PSMC3	2777
TNFRSF1B	2930
PSMD13	3304
RELB	3360
PSMB7	3558
PSMD4	3642
PSMD2	3699
TRAF3	4031
TNFRSF8	4034
PSMA4	4073
CD40	4116
PSMC6	4442
PSMD6	4479
PSMB6	5196
PSMF1	5201
PSMB1	5414
EDAR	6535
TNFRSF13B	6944
TNFSF11	7356
CHUK	7456
TNFSF18	7675
PSMD3	8120
TNFRSF4	9118
PSMB11	9803

---

REACTOME_VISUAL_PHOTOTRANSDUCTION

REACTOME_VISUAL_PHOTOTRANSDUCTION

	473
set	REACTOME_VISUAL_PHOTOTRANSDUCTION
setSize	93
pANOVA	0.00115
s.dist	0.195
p.adjustANOVA	0.07

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CLPS	10683
PDE6G	10662
APOA4	10460
RLBP1	10213
AKR1C1	10187
AKR1B10	10077
GNGT1	10046
GUCA1A	9914
GPIHBP1	9877
PDE6B	9851
SDC4	9285
RHO	9068
APOA2	9060
LRP1	8698
GUCA1B	8669
GPC1	8651
LRP10	8587
LRP8	8544
GRK7	8355
SAG	8311

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CLPS	10683
PDE6G	10662
APOA4	10460
RLBP1	10213
AKR1C1	10187
AKR1B10	10077
GNGT1	10046
GUCA1A	9914
GPIHBP1	9877
PDE6B	9851
SDC4	9285
RHO	9068
APOA2	9060
LRP1	8698
GUCA1B	8669
GPC1	8651
LRP10	8587
LRP8	8544
GRK7	8355
SAG	8311
SDR9C7	8267
APOE	8250
RPE65	7891
MYO7A	7822
OPN1SW	7455
AKR1C3	7395
STRA6	7217
APOM	6588
PLB1	6566
GPC2	6489
RBP3	6091
HSPG2	6016
APOC3	5769
GUCY2D	5655
CNGA1	5645
DHRS3	5341
APOA1	5027
NAPEPLD	5011
SDC1	4882
RDH16	4784
RDH11	4714
CNGB1	4460
GUCA1C	4424
TTR	3955
GNB1	3778
CALM1	3777
FNTB	3742
PRKCA	3721
SLC24A1	3649
AGRN	3030
GRK1	2365
RDH5	2201
GNAT1	1311
ABCA4	1089
PNLIP	1077
AKR1C4	1039
APOB	682
RGS9	571
GPC5	26
NMT2	-293
RBP2	-615
METAP2	-1015
LRP2	-1265
LDLR	-1310
BCO2	-1593
GRK4	-1824
PRKCQ	-2494
NMT1	-2689
RDH10	-3342
GNB5	-3412
CYP4V2	-3456
GPC6	-3484
METAP1	-4158
HSD17B1	-4198
RDH12	-4375
PDE6A	-4428
RCVRN	-4980
CAMKMT	-5483
RGS9BP	-5863
BCO1	-6116
DHRS9	-6143
FNTA	-6766
LRP12	-6843
HSD17B6	-7395
SDC3	-7400
RETSAT	-7976
RBP4	-7989
SDC2	-8430
RBP1	-8440
LPL	-9198
RDH8	-9602
LRAT	-10076
APOC2	-10151

---

REACTOME_INNATE_IMMUNE_SYSTEM

REACTOME_INNATE_IMMUNE_SYSTEM

	227
set	REACTOME_INNATE_IMMUNE_SYSTEM
setSize	1002
pANOVA	0.00126
s.dist	-0.0602
p.adjustANOVA	0.0708

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IFNA7	-11052
SFTPA2	-11036
TYROBP	-11000
PYCARD	-10974
KLRD1	-10968
FOLR3	-10965
RNASE3	-10959
MPO	-10919
ORM1	-10916
AZU1	-10898
C1QA	-10844
FGR	-10840
CD177	-10796
B4GALT1	-10778
SEMG1	-10770
PRTN3	-10766
CTSG	-10743
HTN1	-10726
CD300LB	-10563
MS4A3	-10562

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IFNA7	-11052.0
SFTPA2	-11036.0
TYROBP	-11000.0
PYCARD	-10974.0
KLRD1	-10968.0
FOLR3	-10965.0
RNASE3	-10959.0
MPO	-10919.0
ORM1	-10916.0
AZU1	-10898.0
C1QA	-10844.0
FGR	-10840.0
CD177	-10796.0
B4GALT1	-10778.0
SEMG1	-10770.0
PRTN3	-10766.0
CTSG	-10743.0
HTN1	-10726.0
CD300LB	-10563.0
MS4A3	-10562.0
CEACAM6	-10557.0
IL1B	-10551.0
POLR3GL	-10547.0
AGPAT2	-10520.0
IRAK3	-10511.0
CEACAM3	-10436.0
NLRC4	-10434.0
C5AR2	-10415.0
FPR2	-10404.0
SLPI	-10403.0
ACTB	-10373.0
PLEKHO2	-10334.0
LCP2	-10311.0
FCGR3A	-10294.0
HEBP2	-10287.0
CD63	-10282.0
DEFB118	-10275.0
ATP6V0E2	-10271.0
PRDX6	-10239.0
CTSL	-10181.0
BST2	-10179.0
RAB27A	-10161.0
TIFA	-10144.0
STBD1	-10068.0
VAT1	-10065.0
UBA3	-10057.0
CD209	-10049.0
NDUFC2	-10036.0
EPPIN-WFDC6	-10006.0
ITK	-9992.0
UBE2M	-9955.0
HSPA1A	-9954.0
DEFB1	-9946.0
MME	-9945.0
CD33	-9911.0
IFI16	-9907.0
CTSZ	-9893.0
TREX1	-9889.0
ILF2	-9864.0
CPNE3	-9854.0
TBC1D10C	-9849.0
OSTF1	-9801.0
S100A7A	-9793.0
TICAM2	-9788.0
CRCP	-9783.0
GLIPR1	-9747.0
HSPA1B	-9743.0
SERPINB1	-9739.0
RAP1A	-9737.0
TREM2	-9736.0
MUC15	-9718.0
MEFV	-9710.0
CXCL1	-9709.0
UBB	-9702.0
DEFB128	-9679.0
RAB3D	-9672.0
CTSD	-9665.0
PTPN11	-9664.0
CD46	-9649.0
PPBP	-9638.0
STING1	-9618.0
FTL	-9580.0
CR2	-9554.0
HSPA8	-9533.0
UBA7	-9526.0
GMFG	-9525.0
TMEM30A	-9511.0
C1QC	-9465.0
BIN2	-9442.0
PIK3R2	-9426.0
POLR2K	-9413.0
PSMC4	-9362.0
CCR2	-9318.0
ATP6V1B2	-9288.0
DEFB127	-9230.0
B2M	-9228.0
CD68	-9221.0
TMEM179B	-9212.0
TARM1	-9204.0
NRAS	-9202.0
RNF125	-9173.0
SKP1	-9156.0
CASP8	-9058.0
ATP6V0A1	-9055.0
TBK1	-9043.0
PPP3CB	-9019.0
KLRK1	-8998.0
RHOG	-8996.0
DEFB119	-8941.0
NFKBIA	-8939.0
CASP10	-8927.0
S100A12	-8914.0
UNC13D	-8905.0
STOM	-8904.0
PSTPIP1	-8903.0
CFD	-8891.0
BRI3	-8824.0
ITPR1	-8823.0
TMBIM1	-8795.0
TMC6	-8793.0
PSMA8	-8792.0
TREM1	-8748.0
OLR1	-8670.0
RNF135	-8627.0
CD14	-8611.0
RAC1	-8610.0
TUBB4B	-8604.0
HP	-8533.0
COMMD3	-8517.0
CDA	-8495.0
LAT2	-8462.0
DEFA4	-8452.0
GYG1	-8450.0
TUBB	-8449.0
FADD	-8431.0
POLR3F	-8422.0
MALT1	-8406.0
MS4A2	-8397.0
NOD2	-8386.0
SIGIRR	-8358.0
S100A8	-8349.0
DEFB124	-8332.0
ATP6V1E1	-8322.0
HBB	-8277.0
NLRP3	-8233.0
FCGR3B	-8230.0
UBE2V1	-8226.0
ICAM2	-8211.0
UBE2N	-8206.0
SNAP29	-8138.0
GDI2	-8131.0
CD300A	-8106.0
MUC12	-8040.0
PLAU	-8031.0
EPPIN	-8011.0
TCN1	-8007.0
TOMM70	-8001.0
C6	-7991.0
TLR3	-7985.0
UBC	-7974.0
FCER1A	-7952.0
P2RX1	-7942.0
PIK3C3	-7928.0
FTH1	-7920.0
MAPK10	-7890.0
POLR3H	-7886.0
PLAC8	-7850.0
RAP2B	-7844.0
PSMD12	-7843.0
SHC1	-7816.0
TEC	-7793.0
PGAM1	-7791.0
PGM2	-7742.0
MAPK1	-7718.0
SNAP23	-7715.0
CR1	-7714.0
CD55	-7710.0
ACTG1	-7705.0
CLEC10A	-7696.0
ELANE	-7685.0
DSN1	-7562.0
SAA1	-7546.0
MGST1	-7525.0
SVIP	-7463.0
ENPP4	-7448.0
POLR1C	-7446.0
CTSC	-7436.0
PSMB10	-7431.0
PSMC5	-7419.0
CCL22	-7402.0
POLR2L	-7397.0
SYK	-7342.0
ATG5	-7325.0
LYN	-7312.0
DEFB136	-7298.0
BCL10	-7267.0
MAP3K8	-7243.0
CLEC12A	-7216.0
DEFB133	-7202.0
CAPZA2	-7182.0
LGMN	-7162.0
IRAK2	-7144.0
EEA1	-7135.0
PELI3	-7104.0
PSMB4	-7098.0
LAIR1	-7085.0
NCKAP1	-7050.0
SIGLEC5	-7023.0
YES1	-6977.0
GNLY	-6960.0
RPS6KA1	-6926.0
TLR1	-6921.0
HERC5	-6920.0
TXNIP	-6880.0
CD59	-6877.0
ELMO2	-6841.0
IFIH1	-6817.0
HSP90AB1	-6813.0
PSME4	-6754.0
C8A	-6686.0
CLEC5A	-6654.0
CD58	-6563.0
SURF4	-6524.0
UBE2D2	-6483.0
HCK	-6454.0
MAPKAPK3	-6451.0
SELL	-6407.0
SUGT1	-6392.0
FCN3	-6344.0
NCF2	-6315.0
CASP9	-6274.0
DUSP3	-6269.0
IQGAP2	-6264.0
MAPK14	-6253.0
HLA-E	-6243.0
IDH1	-6229.0
GAB2	-6223.0
CTSA	-6212.0
FABP5	-6211.0
TNFAIP6	-6156.0
TRIM4	-6154.0
PPP3R1	-6142.0
RAB31	-6141.0
LIMK1	-6124.0
ATG12	-6101.0
GPR84	-6093.0
PSMC2	-6092.0
PSME2	-6084.0
CAND1	-6062.0
PLD1	-6055.0
PTPRC	-6035.0
HGSNAT	-6015.0
TNFAIP3	-6008.0
HSP90AA1	-6002.0
PSMA3	-5986.0
CAPZA1	-5977.0
CDK13	-5894.0
POLR3G	-5876.0
USP18	-5857.0
HTN3	-5848.0
PSMB8	-5844.0
ATP6V1C1	-5753.0
PIK3R1	-5752.0
CYB5R3	-5740.0
PGLYRP1	-5709.0
KPNB1	-5688.0
WIPF3	-5681.0
HMGB1	-5679.0
TICAM1	-5674.0
BPI	-5577.0
RAB10	-5576.0
MEF2C	-5570.0
ACTR10	-5559.0
RASGRP4	-5531.0
UBE2K	-5520.0
FBXW11	-5451.0
FCER1G	-5416.0
ERP44	-5387.0
CLEC7A	-5354.0
MAP3K7	-5328.0
LRRFIP1	-5326.0
LRG1	-5273.0
NHLRC3	-5269.0
CLEC4A	-5259.0
ASAH1	-5187.0
CNN2	-5172.0
SLC27A2	-5171.0
SLC15A4	-5149.0
MAP3K1	-5102.0
CCR6	-5028.0
FYN	-5019.0
OSCAR	-5015.0
FGA	-4994.0
SRP14	-4955.0
PA2G4	-4948.0
STK11IP	-4938.0
CPN1	-4906.0
ACTR2	-4881.0
MIF	-4836.0
DNM3	-4834.0
GRN	-4819.0
NFATC2	-4753.0
NPC2	-4745.0
HLA-B	-4701.0
VRK3	-4659.0
NCK1	-4603.0
RPS6KA5	-4598.0
RAB14	-4572.0
C4A	-4568.5
C4B	-4568.5
UBE2L6	-4548.0
P2RX7	-4534.0
KCMF1	-4528.0
ISG15	-4511.0
SCAMP1	-4482.0
PRCP	-4459.0
PSMA5	-4438.0
CUL1	-4436.0
EEF1A1	-4419.0
RAB37	-4408.0
UBA52	-4361.0
NME2	-4359.0
S100A7	-4344.0
PTX3	-4332.0
PSMD11	-4325.0
PGM1	-4322.0
PAFAH1B2	-4319.0
CTSV	-4312.0
DEFB116	-4299.0
IMPDH1	-4285.0
PSMD5	-4244.0
PPP2CB	-4240.0
NFATC3	-4233.0
ATP6V1D	-4203.0
NKIRAS2	-4199.0
WASL	-4194.0
CSTB	-4183.0
BIRC3	-4172.0
ATP6V1G1	-4171.0
TRIM56	-4147.0
CRISPLD2	-4112.0
CASP1	-4103.0
PCBP2	-4088.0
ATOX1	-4080.0
HLA-A	-4075.0
SDCBP	-4069.0
RETN	-4043.0
C4BPA	-4042.0
ARPC5	-4011.0
PSMD9	-3987.0
PTPN6	-3922.0
DYNLT1	-3917.0
LCK	-3915.0
CFHR5	-3904.0
ARMC8	-3892.0
GCA	-3866.0
C1R	-3830.0
ALDH3B1	-3805.0
TNIP2	-3790.0
PTPRB	-3772.0
APRT	-3762.0
PTPRJ	-3725.0
ALOX5	-3720.0
SYNGR1	-3682.0
RNASE8	-3675.0
PAK1	-3644.0
S100A9	-3635.0
DEGS1	-3628.0
NCKAP1L	-3603.0
PRKACB	-3597.0
SERPINB3	-3578.0
FUCA1	-3564.0
YPEL5	-3493.0
BCL2L1	-3491.0
DSP	-3433.0
PSMA6	-3425.0
CRP	-3417.0
DNAJC13	-3414.0
RAB24	-3380.0
ADGRE3	-3339.0
IRAK4	-3272.0
RAB6A	-3224.0
NFKB1	-3211.0
IKBIP	-3187.0
GGH	-3154.0
APP	-3117.0
MYD88	-3102.0
DUSP6	-3092.0
PLCG2	-3090.0
PSMC1	-3076.0
PSME3	-3024.0
MUC21	-3014.0
GRB2	-2984.0
DHX36	-2973.0
PSMB9	-2972.0
TANK	-2941.0
VAV3	-2932.0
GNS	-2916.0
CEP290	-2898.0
UBE2D3	-2867.0
NF2	-2828.0
CDC42	-2824.0
DYNLL1	-2813.0
SLC2A3	-2778.0
PELI2	-2762.0
MYO10	-2716.0
ARPC4	-2710.0
USP14	-2709.0
MAP2K3	-2693.0
NIT2	-2655.0
MAPKAPK2	-2623.0
POLR3K	-2621.0
CREB1	-2614.0
DEFB121	-2609.0
WIPF1	-2579.0
NFKBIB	-2561.0
GSDME	-2537.0
ITPR2	-2510.0
PRKCQ	-2494.0
RHOF	-2467.0
NCSTN	-2437.0
PPP2CA	-2430.0
SERPING1	-2320.0
TXN	-2287.0
DEFA5	-2270.0
TLR6	-2258.0
IRAG2	-2252.0
HK3	-2246.0
TIMP2	-2222.0
CCT2	-2164.0
PRSS3	-2139.0
PSMD1	-2120.0
PRKCSH	-2092.0
SIKE1	-2034.0
ATP6V1F	-2015.0
CCT8	-1952.0
DEFB134	-1948.0
BIRC2	-1940.0
MAPK13	-1892.0
DSG1	-1889.0
ATP8A1	-1816.0
BRK1	-1814.0
FPR1	-1811.0
LILRA3	-1808.0
PSAP	-1802.0
LEAP2	-1783.0
IRF7	-1775.0
PSMB5	-1772.0
BPIFB1	-1771.0
MAVS	-1768.0
POLR3C	-1730.0
CD44	-1715.0
MMP8	-1704.0
NOD1	-1677.0
XRCC6	-1669.0
VCP	-1618.0
WIPF2	-1592.0
LPO	-1584.0
PSMA1	-1545.0
RPS27A	-1544.0
CSNK2B	-1533.0
PIN1	-1506.0
NKIRAS1	-1504.0
MMP9	-1485.0
XRCC5	-1476.0
C7	-1470.0
CYLD	-1457.0
PLD2	-1453.0
CGAS	-1445.0
MUC7	-1442.0
TAB2	-1440.0
TLR2	-1428.0
CD47	-1418.0
SIGLEC15	-1398.0
MANBA	-1393.0
KRAS	-1382.0
PSMB3	-1361.0
C9	-1339.0
GRAP2	-1305.0
RAB3A	-1300.0
PDAP1	-1290.0
LILRB2	-1284.0
GHDC	-1267.0
PSEN1	-1262.0
ATP6V1A	-1254.0
VAPA	-1190.0
CD93	-1169.0
TP53	-1167.0
RNF216	-1156.0
SERPINA3	-1142.0
RAB5B	-1135.0
SLC11A1	-1121.0
PLPP5	-1116.0
DEFB123	-1111.0
RAP1B	-1070.0
ROCK1	-1011.0
SLCO4C1	-965.0
SARM1	-845.0
ATP8B4	-826.0
C5AR1	-817.0
TRIM25	-816.0
RIPK3	-810.0
SERPINB10	-803.0
CFL1	-741.0
PROS1	-731.0
PIK3CA	-717.0
TRIM32	-706.0
ARPC2	-698.0
ELMO1	-685.0
GOLGA7	-674.0
PSME1	-658.0
CLEC4E	-657.0
ATP6V1H	-645.0
CXCR2	-642.0
TRAPPC1	-630.0
IFNA6	-577.0
CD36	-543.0
MYH2	-519.0
DUSP4	-512.0
TLR10	-508.0
TLR4	-494.0
DHX9	-483.0
C3AR1	-468.0
HEXB	-467.0
TMEM63A	-459.0
IST1	-439.0
ATP6V0E1	-419.0
CPB2	-417.0
CFHR4	-415.0
DNM1	-402.0
VAV1	-400.0
FUCA2	-370.0
LTF	-341.0
SLC44A2	-331.0
APAF1	-322.0
DDX41	-304.0
MRE11	-301.0
DUSP7	-261.0
ORM2	-204.0
TRAF6	-191.0
KRT1	-182.0
AIM2	-167.0
LTA4H	-146.0
CTSH	-95.0
ABL1	-86.0
ATF2	-41.0
CST3	-34.0
MAPK7	-30.0
SEM1	-1.0
PPP3CA	3.0
IRF3	23.0
CYBA	64.0
TAX1BP1	75.0
PECAM1	82.0
COLEC10	96.0
NFKB2	109.0
HPSE	155.0
HSP90B1	178.0
POLR3D	190.0
CNPY3	269.0
LYZ	292.0
PSMD8	315.0
ABI1	372.0
MAP2K1	378.0
NOS1	388.0
ADGRG3	399.0
JUN	408.0
JUP	578.0
PRKCD	639.0
DEFB125	679.0
APOB	682.0
CHIT1	687.0
MUC13	704.0
MAPK12	754.0
REG3G	763.0
FRK	777.0
EP300	781.0
GLB1	792.0
BTRC	810.0
PRKCE	835.0
RAC2	892.0
DOCK1	898.0
PSMA7	942.0
PLAUR	971.0
AOC1	1008.0
LRRC7	1022.0
PADI2	1038.0
ITGAM	1055.0
GM2A	1057.0
PSMA2	1059.0
ABI2	1074.0
RNASE7	1079.0
MAP2K6	1098.0
CPPED1	1148.0
PSMD7	1158.0
FGB	1189.0
OLFM4	1200.0
PPP2R1A	1222.0
GSTP1	1223.0
ATP6V0D2	1254.0
DYNC1LI1	1261.0
COMMD9	1275.0
ADAM10	1278.0
TXNDC5	1340.0
AMPD3	1343.0
CAPN1	1356.0
RAB7A	1376.0
WASF1	1385.0
FCAR	1424.0
BST1	1460.0
ARPC3	1491.0
AHCYL1	1560.0
PSMB2	1566.0
RNASE6	1577.0
ARPC1A	1584.0
ARHGAP9	1588.0
ARSB	1595.0
MCEMP1	1597.0
QPCT	1624.0
HLA-C	1645.0
RHOA	1702.0
DIAPH1	1732.0
ATP6V0A2	1769.0
PTK2	1793.0
C1orf35	1802.0
PLA2G2A	1803.0
DTX4	1910.0
PNP	1934.0
ATP6V0C	1942.0
GSDMD	1972.0
FGG	2001.0
MAN2B1	2003.0
MAP3K14	2022.0
DERA	2053.0
DNM2	2057.0
CYSTM1	2077.0
POLR2E	2087.0
BCL2	2097.0
AGA	2103.0
WASF2	2119.0
MVP	2136.0
ALDOA	2190.0
DEFB129	2275.0
ORMDL3	2313.0
ANO6	2315.0
ATP6V1C2	2355.0
ARSA	2362.0
PSMD14	2369.0
PIK3R4	2389.0
PKM	2420.0
ABCA13	2463.0
TXK	2522.0
TRAF2	2552.0
S100P	2562.0
ADGRE5	2581.0
VNN1	2605.0
ARG1	2628.0
TRIM21	2664.0
CXCR1	2708.0
ATF1	2712.0
POLR1D	2715.0
PELI1	2717.0
N4BP1	2722.0
CAP1	2748.0
RASGRP1	2753.0
PYGL	2776.0
PSMC3	2777.0
POLR2H	2784.0
TSPAN14	2791.0
ITGB2	2817.0
C5	2820.0
ACLY	2846.0
SIGLEC14	2871.0
CRK	2872.0
ALAD	2921.0
TNFRSF1B	2930.0
CFH	2931.0
STK10	2939.0
MAPK11	2972.0
RNASE2	2974.0
CLU	2978.0
C1S	2988.0
CD247	3071.0
PTAFR	3097.0
POLR3A	3104.0
IKBKE	3105.0
ACP3	3144.0
ITGAL	3181.0
C8B	3183.0
CD300E	3212.0
RIGI	3277.0
PSMD13	3304.0
HVCN1	3320.0
MAPK8	3348.0
RELB	3360.0
C3	3375.0
ACTR3	3379.0
MGAM	3381.0
SOS1	3385.0
ECSIT	3400.0
REG3A	3458.0
CTNNB1	3514.0
MUC17	3523.0
MASP1	3531.0
WASF3	3553.0
CTSK	3556.0
PSMB7	3558.0
C6orf120	3570.0
CRACR2A	3602.0
MUC1	3626.0
PSMD4	3642.0
PSMD2	3699.0
CMTM6	3702.0
IFNA14	3716.0
ATP6V1E2	3746.0
VAMP8	3770.0
CALM1	3777.0
COPB1	3834.0
POLR3B	3854.0
MNDA	3886.0
GSN	3907.0
ITGAX	3938.0
TTR	3955.0
ITCH	3965.0
NOS2	3966.0
CD53	4004.0
TRAF3	4031.0
PSMA4	4073.0
MUCL1	4095.0
RNASET2	4097.0
ATAD3B	4106.0
CKAP4	4122.0
HRNR	4145.0
MYO5A	4170.0
ATP11B	4214.0
DEFB104A	4232.5
DEFB104B	4232.5
DEFB135	4239.0
PTPRN2	4257.0
TLR5	4268.0
FAF2	4269.0
SIRPA	4294.0
SOCS1	4311.0
PRKACA	4352.0
IKBKB	4370.0
TIRAP	4386.0
PSMC6	4442.0
NFAM1	4448.0
FCGR2A	4453.0
TRPM2	4465.0
PSMD6	4479.0
MEF2A	4487.0
RPS6KA2	4563.0
RIPK2	4589.0
LAT	4596.0
NOS3	4602.0
BPIFA1	4613.0
UBE2D1	4660.0
ICAM3	4713.0
COLEC11	4734.0
ADAM8	4779.0
MAPK9	4786.0
IQGAP1	4824.0
PGLYRP2	4883.0
CARD9	4884.0
DCD	4915.0
FOS	4918.0
ATG7	4944.0
CAT	4947.0
VCL	4950.0
IGF2R	4957.0
CASP2	4962.0
AP2A2	4969.0
CAB39	4978.0
SERPINB12	4990.0
LAMTOR2	5007.0
MUC3A	5090.0
PPIA	5114.0
BPIFB4	5163.0
VPS35L	5179.0
PSMB6	5196.0
PSMF1	5201.0
LRRC14	5202.0
GPI	5203.0
S100A11	5224.0
SLC2A5	5244.0
PPP2R5D	5283.0
ATP6V1G2	5302.0
CANT1	5319.0
AGL	5329.0
PRKDC	5384.0
CREG1	5385.0
RAB5C	5408.0
PSMB1	5414.0
ARPC1B	5423.0
MYH9	5470.0
NCR2	5541.0
CEACAM8	5558.0
PAK2	5575.0
CAMP	5602.0
IFNA2	5611.0
SNAP25	5636.0
LY86	5641.0
IFNA21	5650.0
AAMP	5668.0
HMOX2	5676.0
MUC5B	5682.0
DNAJC3	5724.0
IMPDH2	5742.0
RAB4B	5766.0
CFB	5820.0
EEF2	5833.0
PI3	5856.0
NCF4	5860.0
PLPP4	5870.0
ANXA2	5910.0
C2	6058.0
ATP6V1B1	6093.0
PGLYRP4	6188.0
NEU1	6199.0
MAPK3	6201.0
RAF1	6216.0
ATP6V1G3	6253.0
ADA2	6257.0
DEFB126	6267.0
NCKIPSD	6388.0
CPNE1	6392.0
ITGAV	6399.0
NLRX1	6433.0
MUC16	6462.0
MUC20	6465.0
DNAJC5	6554.0
DEFB115	6563.0
HMOX1	6570.0
LAMTOR1	6612.0
DEFB113	6617.0
IFNB1	6637.0
F2	6639.0
POLR2F	6656.0
ATP6V0A4	6666.0
CD180	6668.0
LAMTOR3	6679.0
CLEC6A	6706.0
IFNA13	6710.0
RASGRP2	6728.0
AP1M1	6753.0
PPIE	6772.0
DEFB132	6778.0
ANPEP	6794.0
PDXK	6833.0
STAT6	6841.0
UBR4	6878.0
SIGLEC9	6884.0
PIK3CB	6910.0
ALPK1	6923.0
IFNA5	6924.0
CYFIP1	6938.0
PKP1	6973.0
C8G	6991.0
MAP2K4	6996.0
SERPINB6	7046.0
ALDOC	7063.0
PGLYRP3	7072.0
UNC93B1	7097.0
TKFC	7102.0
PLD4	7141.0
PIGR	7170.0
LILRB3	7182.0
NFASC	7207.0
IFNA8	7263.0
PLA2G6	7280.0
TOM1	7299.0
VTN	7308.0
CASP4	7309.0
MYO1C	7342.0
RAB18	7374.0
PRG3	7392.0
MBL2	7413.0
CHUK	7456.0
ACTR1B	7503.0
CFI	7510.0
DDOST	7512.0
DPP7	7516.0
CD19	7530.0
CYFIP2	7531.0
LAMP1	7541.0
NLRP1	7574.0
PTPN4	7596.0
CARD11	7605.0
MUC6	7631.0
CD4	7638.0
RELA	7644.0
TOLLIP	7660.0
CHI3L1	7670.0
C4BPB	7682.0
QSOX1	7693.0
DBNL	7728.0
S100B	7729.0
CHRNB4	7776.0
HSPA6	7793.0
LBP	7851.0
MUC5AC	7860.0
PLD3	7909.0
CD81	7961.0
PTGES2	7967.0
MMP25	8051.0
MLEC	8067.0
IFNA1	8075.0
NLRC5	8083.0
LGALS3	8085.0
SERPINA1	8101.0
DOCK2	8104.0
ATP6V0B	8105.0
PSMD3	8120.0
CTSB	8142.0
ITPR3	8146.0
DHX58	8155.0
SPTAN1	8195.0
RBSN	8224.0
TAB1	8248.0
PANX1	8272.0
LY96	8281.0
S100A1	8313.0
POLR3E	8328.0
AGER	8360.0
CHGA	8366.0
DOK3	8382.0
CTSS	8394.0
CDC34	8395.0
MAP2K7	8419.0
ARHGAP45	8432.0
HRAS	8450.0
NLRC3	8465.0
FCN2	8521.0
SIRPB1	8561.0
PDPK1	8583.0
COTL1	8605.0
NLRP4	8614.0
CLEC4D	8704.0
SRC	8731.0
MYO9B	8756.0
PFKL	8763.0
AHSG	8810.0
PYGB	8818.0
NFATC1	8856.0
LPCAT1	8866.0
ACAA1	8902.0
FLG2	8912.0
PPP2R1B	8914.0
FGL2	8922.0
CCL17	8925.0
BAIAP2	8966.0
GUSB	8973.0
ARL8A	8991.0
DYNC1H1	9026.0
NBEAL2	9031.0
PLCG1	9033.0
CREBBP	9058.0
MUC4	9126.0
ATP6V0D1	9150.0
RIPK1	9165.0
ATP11A	9217.0
ITLN1	9246.0
A1BG	9252.0
DEFA6	9272.0
CRISP3	9303.0
KCNAB2	9306.0
CLEC4C	9403.0
BPIFA2	9417.0
NAPRT	9433.0
GZMM	9572.0
SFTPA1	9579.0
CFHR2	9608.0
RAB44	9723.0
CEACAM1	9732.0
TCIRG1	9742.0
PSMB11	9803.0
GAA	9823.0
MASP2	9841.0
LCN2	9859.0
DEFB110	9885.0
APEH	9887.0
BPIFB2	9891.0
PRG2	9922.0
DGAT1	9960.0
FCN1	9969.0
ART1	10041.0
VAV2	10056.0
IFNA16	10109.0
TLR9	10162.0
GALNS	10173.0
SFTPD	10196.0
C1QB	10269.0
PRKACG	10288.0
CPN2	10331.0
ZBP1	10449.0
CD3G	10501.0
CALML5	10611.0
BPIFB6	10706.0
DSC1	10741.0
DEFB114	10749.0
EPX	10849.0

---

REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_HSCS

REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_HSCS

	1282
set	REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_HSCS
setSize	121
pANOVA	0.00128
s.dist	-0.169
p.adjustANOVA	0.0708

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GATA2	-10325
H2AC20	-10322
UBB	-9702
H2AX	-9652
CCNH	-9414
H4C8	-9377
PSMC4	-9362
H3-3A	-9072
H2BC21	-9064
H2BC5	-8892
PSMA8	-8792
YAP1	-8707
LMO2	-8617
H4C3	-8439
H3C10	-7994
UBC	-7974
TAL1	-7932
H2BC11	-7869
PSMD12	-7843
H2BC14	-7552

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GATA2	-10325.0
H2AC20	-10322.0
UBB	-9702.0
H2AX	-9652.0
CCNH	-9414.0
H4C8	-9377.0
PSMC4	-9362.0
H3-3A	-9072.0
H2BC21	-9064.0
H2BC5	-8892.0
PSMA8	-8792.0
YAP1	-8707.0
LMO2	-8617.0
H4C3	-8439.0
H3C10	-7994.0
UBC	-7974.0
TAL1	-7932.0
H2BC11	-7869.0
PSMD12	-7843.0
H2BC14	-7552.0
PSMB10	-7431.0
PSMC5	-7419.0
H2BC17	-7263.0
PSMB4	-7098.0
H2BC4	-7072.0
H3-3B	-6937.0
H3C2	-6790.0
PSME4	-6754.0
H2AJ	-6672.0
H2BC13	-6590.0
LMO1	-6508.0
H2AC8	-6445.0
H2AC7	-6250.5
H2BC7	-6250.5
H2AC6	-6100.0
PSMC2	-6092.0
PSME2	-6084.0
H2BC8	-5989.0
PSMA3	-5986.0
GATA3	-5922.0
PSMB8	-5844.0
H2AC18	-5704.5
H2AC19	-5704.5
H3C4	-5557.0
H2AC14	-5481.0
H3C12	-5090.0
PSMA5	-4438.0
UBA52	-4361.0
PSMD11	-4325.0
PSMD5	-4244.0
H2BC6	-4207.0
H4C6	-4120.0
SPI1	-4047.0
PSMD9	-3987.0
RUNX1	-3889.0
H3C11	-3817.0
KMT2A	-3737.0
CDK7	-3687.0
PSMA6	-3425.0
H4C13	-3097.0
PSMC1	-3076.0
PSME3	-3024.0
PSMB9	-2972.0
H2AZ2	-2221.0
PSMD1	-2120.0
PSMB5	-1772.0
PSMA1	-1545.0
RPS27A	-1544.0
H2AZ1	-1527.0
PSMB3	-1361.0
MNAT1	-1328.0
H4C2	-1183.0
CBFB	-1044.0
H4C1	-737.0
PSME1	-658.0
H4C5	-618.0
H2BC15	-371.0
MYB	-365.0
ABL1	-86.0
H2BC1	-54.0
SEM1	-1.0
PSMD8	315.0
LDB1	472.0
H2BC12	672.0
PSMA7	942.0
PSMA2	1059.0
PSMD7	1158.0
PSMB2	1566.0
PSMD14	2369.0
PSMC3	2777.0
H2AC4	2947.0
H4C16	3253.0
PSMD13	3304.0
PSMB7	3558.0
PSMD4	3642.0
PSMD2	3699.0
ITCH	3965.0
PSMA4	4073.0
H3C1	4262.0
PSMC6	4442.0
PSMD6	4479.0
TP73	4484.0
H2BC26	4643.0
PSMB6	5196.0
PSMF1	5201.0
H4C9	5218.0
H2BC9	5307.5
H3C7	5307.5
PSMB1	5414.0
TCF12	5998.0
H4C4	6524.0
H3C6	6602.0
H4C12	7358.0
PSMD3	8120.0
H2BC3	8253.0
H3C3	9119.0
H2BC10	9234.0
H4C11	9599.0
PSMB11	9803.0
H3C8	9880.0
TCF3	10398.0

---

REACTOME_FASL_CD95L_SIGNALING

REACTOME_FASL_CD95L_SIGNALING

	1187
set	REACTOME_FASL_CD95L_SIGNALING
setSize	5
pANOVA	0.00129
s.dist	-0.831
p.adjustANOVA	0.0708

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FASLG	-10891
CASP8	-9058
CASP10	-8927
FAS	-8637
FADD	-8431

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FASLG	-10891
CASP8	-9058
CASP10	-8927
FAS	-8637
FADD	-8431

---

REACTOME_INFECTIOUS_DISEASE

REACTOME_INFECTIOUS_DISEASE

	974
set	REACTOME_INFECTIOUS_DISEASE
setSize	910
pANOVA	0.00147
s.dist	-0.0622
p.adjustANOVA	0.0778

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IFNA7	-11052
PYCARD	-10974
FGR	-10840
CTSG	-10743
RPL29	-10734
STX1A	-10640
IL1B	-10551
GPS2	-10539
GNG8	-10525
HBEGF	-10493
RPS12	-10480
ACTB	-10373
H2AC20	-10322
FCGR3A	-10294
CHMP4C	-10227
ZCRB1	-10186
CTSL	-10181
BST2	-10179
NUP50	-10150
IFNAR2	-10060

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IFNA7	-11052.0
PYCARD	-10974.0
FGR	-10840.0
CTSG	-10743.0
RPL29	-10734.0
STX1A	-10640.0
IL1B	-10551.0
GPS2	-10539.0
GNG8	-10525.0
HBEGF	-10493.0
RPS12	-10480.0
ACTB	-10373.0
H2AC20	-10322.0
FCGR3A	-10294.0
CHMP4C	-10227.0
ZCRB1	-10186.0
CTSL	-10181.0
BST2	-10179.0
NUP50	-10150.0
IFNAR2	-10060.0
RPS25	-9996.0
HSPA1A	-9954.0
FXYD7	-9898.0
GNAI1	-9892.0
CLTA	-9790.0
RPL12	-9789.0
GNG13	-9775.0
VPS18	-9717.0
MEFV	-9710.0
UBB	-9702.0
SUMO1	-9697.0
TUBB6	-9696.0
PTPN11	-9664.0
GNGT2	-9625.0
STING1	-9618.0
IL6R	-9582.0
RPL23	-9573.0
IL17A	-9567.0
ANO3	-9542.0
YWHAE	-9457.0
CCNH	-9414.0
POLR2K	-9413.0
CCR5	-9411.0
GNG11	-9404.0
RPL18	-9396.0
H4C8	-9377.0
PSMC4	-9362.0
B2M	-9228.0
CORO1A	-9215.0
JAK1	-9200.0
RPL10L	-9192.0
RPL13	-9165.0
SKP1	-9156.0
CDH1	-9135.0
H2BC21	-9064.0
CDK9	-9061.0
TBK1	-9043.0
SAR1B	-9005.0
TAF10	-8984.0
RPL10A	-8981.0
GNG5	-8953.0
NFKBIA	-8939.0
TMPRSS2	-8937.0
PSTPIP1	-8903.0
H2BC5	-8892.0
RPS13	-8885.0
NOXO1	-8881.0
PRMT1	-8837.0
TUBA3E	-8829.0
ITPR1	-8823.0
IL6	-8816.0
PSMA8	-8792.0
TUBA1B	-8749.0
RPL24	-8697.0
MVB12A	-8685.0
RPS26	-8630.0
RNF135	-8627.0
RAC1	-8610.0
TUBB4B	-8604.0
RPS6	-8578.0
HNRNPA1	-8516.0
GATAD2B	-8499.0
GEMIN5	-8488.0
RPL41	-8474.0
TUBB	-8449.0
H4C3	-8439.0
SDC2	-8430.0
MTA2	-8428.0
NOD2	-8386.0
NUP42	-8372.0
FEN1	-8359.0
GNAI3	-8338.0
NUP153	-8324.0
FXYD2	-8312.0
HMGA1	-8287.0
RPS28	-8280.0
CALR	-8269.0
RPL13A	-8267.5
NLRP3	-8233.0
UBE2V1	-8226.0
UBE2N	-8206.0
RPL14	-8156.0
RPL11	-8150.0
AAAS	-8141.0
PRKAR2B	-8132.0
GEMIN2	-8084.0
RPL4	-8026.0
RPL7	-8006.0
TOMM70	-8001.0
H3C10	-7994.0
UBC	-7974.0
TUBB2A	-7957.0
PIK3C3	-7928.0
TRIM28	-7887.0
H2BC11	-7869.0
PSMD12	-7843.0
RPL39L	-7836.0
CNBP	-7824.0
GUCY2C	-7783.0
SNRPD1	-7753.0
SAP30	-7748.0
MAPK1	-7718.0
ACTG1	-7705.0
CD163	-7699.0
GTF2F1	-7689.0
FAU	-7687.0
TAF15	-7585.0
H2BC14	-7552.0
IL18	-7504.0
ANO4	-7484.0
HLA-G	-7464.0
MAP1LC3B	-7452.0
PSMB10	-7431.0
DVL2	-7423.0
PSMC5	-7419.0
RPL34	-7413.0
SDC3	-7400.0
POLR2L	-7397.0
LIG4	-7389.0
POLR2D	-7349.0
SYK	-7342.0
RPS15A	-7332.0
MOGS	-7322.0
ELOC	-7318.0
LYN	-7312.0
FURIN	-7294.0
H2BC17	-7263.0
PABPN1	-7259.0
VPS45	-7240.0
ARF1	-7239.0
KPNA7	-7191.0
RPL5	-7169.0
IRAK2	-7144.0
IFNAR1	-7114.0
PSMB4	-7098.0
H2BC4	-7072.0
NCKAP1	-7050.0
CHMP2B	-7022.0
SYT1	-7004.0
GNG2	-6988.0
YES1	-6977.0
KPNA5	-6957.0
SUPT16H	-6940.0
YWHAH	-6931.0
TLR1	-6921.0
RPSA	-6914.0
TAF9	-6894.0
TXNIP	-6880.0
TUBB8	-6855.0
ELMO2	-6841.0
MGAT2	-6833.5
RPL36AL	-6833.5
IFIH1	-6817.0
ANO5	-6816.0
HSP90AB1	-6813.0
H3C2	-6790.0
NPM1	-6785.0
PRKAR1A	-6767.0
FNTA	-6766.0
PSME4	-6754.0
RPL37	-6752.0
RPN1	-6622.0
IL1R1	-6603.0
SUDS3	-6602.0
VAMP1	-6597.0
H2BC13	-6590.0
RPLP0	-6587.0
EDEM2	-6549.0
HDAC2	-6547.0
YWHAZ	-6541.0
POLR2I	-6513.0
TUBB4A	-6499.0
RPL23A	-6481.0
RPL35A	-6473.0
HCK	-6454.0
H2AC8	-6445.0
SUGT1	-6392.0
ATP1B3	-6332.0
RPL21	-6325.0
RPL22L1	-6284.0
MAPK14	-6253.0
H2AC7	-6250.5
H2BC7	-6250.5
HLA-E	-6243.0
TUBB2B	-6175.0
RPS3A	-6158.0
TRIM4	-6154.0
NUP35	-6110.0
H2AC6	-6100.0
PSMC2	-6092.0
PSME2	-6084.0
SMAD4	-6076.0
POM121	-6050.0
HNRNPK	-6034.0
FKBP4	-6005.0
HSP90AA1	-6002.0
H2BC8	-5989.0
PSMA3	-5986.0
RPL17	-5981.0
KPNA2	-5929.0
GEMIN7	-5904.0
SH3GL2	-5875.0
GTF2A2	-5868.0
TUBB3	-5860.0
PSMB8	-5844.0
TAF6	-5820.0
FZD7	-5780.0
GTF2H5	-5748.0
ANO8	-5729.0
RPL27A	-5715.0
H2AC18	-5704.5
H2AC19	-5704.5
KPNB1	-5688.0
WIPF3	-5681.0
RPS24	-5677.0
GNG10	-5599.0
H3C4	-5557.0
SH3GL3	-5552.0
RPL18A	-5525.0
CBX1	-5505.0
VPS37B	-5498.0
H2AC14	-5481.0
APOBEC3G	-5453.0
NUP205	-5439.0
CANX	-5437.0
MET	-5427.0
RPS18	-5357.0
MAP3K7	-5328.0
RAE1	-5266.0
RPL35	-5265.0
PPIB	-5230.0
TUBA1C	-5216.0
IL17RC	-5186.0
TAF13	-5185.0
NCBP2	-5148.0
H3C12	-5090.0
FYN	-5019.0
RPL8	-5017.0
NMI	-4937.0
YWHAQ	-4922.0
SEC24C	-4894.0
ACTR2	-4881.0
SV2C	-4861.0
ATP1B1	-4851.0
RPS20	-4837.0
ELOB	-4810.0
ADAM17	-4731.0
HLA-B	-4701.0
SNF8	-4675.0
NUP37	-4666.0
NUP155	-4621.0
SMAD3	-4614.0
SUPT4H1	-4613.0
NCK1	-4603.0
UBAP1	-4602.0
RPLP2	-4592.0
SEC23A	-4574.0
P2RX7	-4534.0
ISG15	-4511.0
ELOA2	-4505.0
CLTC	-4494.0
NUP133	-4483.0
PSMA5	-4438.0
EEF1A1	-4419.0
UBA52	-4361.0
CSNK1A1	-4349.0
KPNA1	-4347.0
BECN1	-4342.0
PSMD11	-4325.0
WNT5A	-4314.0
RPL28	-4300.0
IMPDH1	-4285.0
PSMD5	-4244.0
IFNGR1	-4243.0
RBBP4	-4237.0
PHF21A	-4225.0
RPS10	-4220.0
H2BC6	-4207.0
WASL	-4194.0
RPS11	-4189.0
DDX20	-4180.0
TAF1L	-4157.0
H4C6	-4120.0
ARID4A	-4118.0
CASP1	-4103.0
PCBP2	-4088.0
HLA-A	-4075.0
CHMP5	-4062.0
AP2B1	-4018.0
ARPC5	-4011.0
PSMD9	-3987.0
PARP4	-3969.0
STAM2	-3940.0
PTPN6	-3922.0
POLR2C	-3916.0
LCK	-3915.0
RPS5	-3903.0
RUNX1	-3889.0
RPL36	-3867.0
ADCY2	-3855.0
TUBA1A	-3854.0
H3C11	-3817.0
VPS37C	-3801.0
AP1S1	-3777.0
PSIP1	-3741.0
H2AC17	-3715.0
CDK7	-3687.0
VPS37A	-3656.0
NCKAP1L	-3603.0
PRKACB	-3597.0
GTF2H1	-3579.0
TAF5	-3574.0
BCL2L1	-3491.0
RPLP1	-3490.0
GPC6	-3484.0
RPL15	-3478.0
PSMA6	-3425.0
GNB5	-3412.0
ARID4B	-3410.0
KEAP1	-3390.0
GTF2A1	-3386.0
G3BP1	-3361.0
CHMP7	-3302.0
RPS29	-3289.0
CTNND1	-3266.0
XRCC4	-3247.0
NFKB1	-3211.0
RBX1	-3122.0
APP	-3117.0
H4C13	-3097.0
PLCG2	-3090.0
PSMC1	-3076.0
RPL19	-3065.0
CBLL1	-3063.0
IFNGR2	-3057.0
PSME3	-3024.0
SFPQ	-2998.0
GRB2	-2984.0
GSK3B	-2980.0
PSMB9	-2972.0
VAV3	-2932.0
NFE2L2	-2909.0
PRKAR2A	-2896.0
SNRPF	-2877.0
GNG4	-2862.0
CDC42	-2824.0
DYNLL1	-2813.0
DYNC1I2	-2792.0
POM121C	-2759.0
PALS1	-2731.0
MYO10	-2716.0
ARPC4	-2710.0
KPNA4	-2708.0
MAP2K3	-2693.0
NMT1	-2689.0
DDX5	-2682.0
AP1G1	-2664.0
RPL9	-2640.0
EGFR	-2625.0
CREB1	-2614.0
PPIH	-2611.0
REST	-2601.0
RPS16	-2594.0
SP1	-2592.0
WIPF1	-2579.0
ADCY8	-2512.0
ITPR2	-2510.0
NUP43	-2489.0
RPL30	-2386.0
RPS15	-2337.0
GEMIN6	-2333.0
TXN	-2287.0
SNRPD2	-2280.0
SAP18	-2267.0
GNB2	-2215.0
SAP30L	-2205.0
CRBN	-2204.0
SRPK1	-2197.0
CCNT2	-2188.0
RPL6	-2141.0
PSMD1	-2120.0
PRKCSH	-2092.0
KPNA3	-2071.0
DYNC1I1	-2041.0
SIKE1	-2034.0
MGAT4C	-2006.0
S1PR1	-1997.0
NDC1	-1937.0
BANF1	-1869.0
RPL3	-1846.0
BRK1	-1814.0
KDM1A	-1810.0
MGAT1	-1806.0
IRF7	-1775.0
HLA-F	-1773.0
PSMB5	-1772.0
MAVS	-1768.0
EIF2AK2	-1726.0
NOD1	-1677.0
XRCC6	-1669.0
RPS2	-1664.0
YWHAG	-1652.0
ANTXR1	-1646.0
VCP	-1618.0
CHMP2A	-1612.0
WIPF2	-1592.0
H2AC21	-1556.0
PSMA1	-1545.0
RPS27A	-1544.0
VHL	-1534.0
TAF4B	-1508.0
CAV1	-1489.0
XRCC5	-1476.0
GTF2E1	-1461.0
GTF2H3	-1441.0
TAB2	-1440.0
TLR2	-1428.0
AP1M2	-1373.0
PSMB3	-1361.0
RPL38	-1357.0
PPIG	-1334.0
MNAT1	-1328.0
RPS8	-1326.0
H2AC13	-1306.0
H2AC11	-1232.0
GRSF1	-1228.0
RPS23	-1205.0
VPS37D	-1203.0
H4C2	-1183.0
ROCK2	-1173.0
EPS15	-1166.0
ZDHHC5	-1162.0
ADCY7	-1153.0
FXYD1	-1144.0
RPL37A	-1087.0
ROCK1	-1011.0
FKBP1A	-1001.0
SNRPE	-904.0
ELOA	-878.0
TRIM25	-816.0
RPS21	-811.0
RIPK3	-810.0
ADCY6	-796.0
ST3GAL3	-760.0
H4C1	-737.0
ATP1A1	-701.0
ARPC2	-698.0
ELMO1	-685.0
GOLGA7	-674.0
PSME1	-658.0
ATP6V1H	-645.0
H4C5	-618.0
ATP1A2	-607.0
GNG12	-579.0
IFNA6	-577.0
GTF2F2	-573.0
MYH2	-519.0
TAF11	-484.0
C3AR1	-468.0
PATJ	-465.0
TAF12	-438.0
VAV1	-400.0
NCBP1	-381.0
H2BC15	-371.0
YWHAB	-355.0
NR3C1	-354.0
LTF	-341.0
STAT1	-317.0
TUBA4B	-299.0
NMT2	-293.0
ATG14	-256.0
GALNT1	-209.0
TRAF6	-191.0
VPS36	-172.0
SNRPD3	-159.0
TBL1XR1	-134.0
RPS9	-121.0
ITGB1	-101.0
ANO2	-91.0
ABL1	-86.0
TSG101	-74.0
H2BC1	-54.0
PLK2	-9.0
SEM1	-1.0
SSRP1	7.0
IRF3	23.0
GPC5	26.0
RPL32	63.0
CYBA	64.0
NUP85	69.0
NUP214	74.0
MGAT5	88.0
CUL3	100.0
NFKB2	109.0
POLR2B	117.0
STT3A	119.0
SV2B	168.0
PDCD6IP	217.0
JAK3	218.0
RCOR1	246.0
G3BP2	277.0
PSMD8	315.0
ABI1	372.0
MAP2K1	378.0
JUN	408.0
MAN2A1	431.0
H2AC1	452.0
SLC25A4	457.0
UVRAG	479.0
DYNC1LI2	507.0
CBL	556.0
VPS41	617.0
NELFE	643.0
TAF2	646.0
ANO9	655.0
VPS33A	658.0
H2BC12	672.0
TCEA1	677.0
TUBA3C	701.0
CHMP6	719.0
EP300	781.0
BTRC	810.0
BRMS1	890.0
DOCK1	898.0
POLR2G	936.0
PSMA7	942.0
ENTPD1	945.0
NT5E	946.0
RANBP1	976.0
ITGA4	980.0
CHMP3	1027.0
ST6GALNAC4	1052.0
PSMA2	1059.0
ATP1B2	1070.0
ABI2	1074.0
MAP2K6	1098.0
TJP1	1115.0
PARP8	1136.0
CCNT1	1152.0
PSMD7	1158.0
ZDHHC11	1166.0
SRPK2	1179.0
GJA1	1183.0
CUL5	1236.0
DYNC1LI1	1261.0
IL1A	1307.0
RAB7A	1376.0
WASF1	1385.0
COMT	1425.0
SEC24B	1426.0
PARP10	1434.0
ARPC3	1491.0
TUSC3	1530.0
GEMIN4	1547.0
NUP107	1548.0
PTGES3	1557.0
AHCYL1	1560.0
PSMB2	1566.0
SYT2	1570.0
CXCR4	1582.0
ARPC1A	1584.0
CHMP4A	1628.0
H2AC12	1635.0
HLA-C	1645.0
GSK3A	1699.0
XPO1	1743.0
RPN2	1748.0
GNB4	1777.0
BLNK	1792.0
PTK2	1793.0
ANTXR2	1864.0
HDAC3	1872.0
RPS7	1873.0
NCOR1	1885.0
TUBA8	1901.0
RNMT	1929.0
RNGTT	1953.0
GSDMD	1972.0
ISCU	2031.0
SEH1L	2049.0
EED	2064.0
POLR2E	2087.0
WASF2	2119.0
LARP1	2175.0
STAM	2256.0
STX1B	2286.0
ANO6	2315.0
SH3GL1	2318.0
UBE2I	2333.0
TRIM27	2336.0
PSMD14	2369.0
PIK3R4	2389.0
VPS25	2401.0
AP1S3	2443.0
TAF3	2448.0
IPO5	2474.0
CCNK	2510.0
CRB3	2566.0
TAF7	2596.0
GNG7	2640.0
TXNRD1	2669.0
H2AC15	2679.0
GTF2H4	2687.0
HMG20B	2702.0
ADCY4	2738.0
NUP88	2756.0
ST3GAL2	2774.0
PSMC3	2777.0
POLR2H	2784.0
PARP9	2789.0
GGT1	2804.0
NUP188	2838.0
CRK	2872.0
NUP160	2878.0
H2AC4	2947.0
AGRN	3030.0
SNRPG	3043.0
CD247	3071.0
CD9	3084.0
IKBKE	3105.0
CYSLTR2	3112.0
SEC24A	3122.0
EZH2	3126.0
TBP	3128.0
CD79A	3133.0
DPEP2	3223.0
H4C16	3253.0
RIGI	3277.0
RPL26L1	3302.0
PSMD13	3304.0
RPL27	3305.0
MAPK8	3348.0
GTF2E2	3352.0
C3	3375.0
ACTR3	3379.0
SOS1	3385.0
GNAS	3484.0
CTNNB1	3514.0
MASP1	3531.0
IL10	3533.0
TPR	3550.0
WASF3	3553.0
PSMB7	3558.0
ZDHHC2	3571.0
PARP16	3579.0
PSMD4	3642.0
PSMD2	3699.0
IFNA14	3716.0
FNTB	3742.0
RPL26	3766.0
TGFB1	3769.0
CALM1	3777.0
GNB1	3778.0
TUFM	3781.0
ST6GALNAC3	3797.0
SEC24D	3821.0
AKT3	3841.0
RPS27L	3876.0
NUP98	3900.0
ITCH	3965.0
NOS2	3966.0
TRAF3	4031.0
PSMA4	4073.0
ADCY9	4117.0
ADCY1	4147.0
MYO5A	4170.0
DAXX	4187.0
ZDHHC20	4223.0
H3C1	4262.0
NRP1	4306.0
RPL7A	4313.0
PRKACA	4352.0
NEDD4L	4363.0
IKBKB	4370.0
VPS33B	4400.0
DYNLL2	4409.0
RAN	4428.0
PSMC6	4442.0
FCGR2A	4453.0
HAVCR1	4468.0
VPS4A	4473.0
PSMD6	4479.0
MBD3	4522.0
RIPK2	4589.0
ELL	4599.0
GNAI2	4610.0
IL17F	4641.0
H2BC26	4643.0
VPS28	4658.0
MGAT4A	4676.0
GATAD2A	4692.0
NELFCD	4723.0
PARP14	4793.0
SDC1	4882.0
NCOR2	4914.0
AP2A2	4969.0
NUP54	4974.0
PARP6	5001.0
PPIA	5114.0
ERCC3	5144.0
PSMB6	5196.0
PSMF1	5201.0
H4C9	5218.0
CHD4	5228.0
SV2A	5230.0
RCC1	5251.0
GTF2B	5276.0
H2BC9	5307.5
H3C7	5307.5
FUT8	5317.0
PSMB1	5414.0
ARPC1B	5423.0
ENO1	5448.0
NUP93	5467.0
MYH9	5470.0
TUBA4A	5539.0
NOXA1	5551.0
PAK2	5575.0
CEBPD	5604.0
VTA1	5607.0
IFNA2	5611.0
SUPT5H	5619.0
ST6GAL1	5626.0
SNAP25	5636.0
ADORA2B	5638.0
IFNA21	5650.0
NELFA	5698.0
FXYD4	5710.0
DNAJC3	5724.0
SIGMAR1	5738.0
IMPDH2	5742.0
LIG1	5744.0
NUP210	5745.0
EEF2	5833.0
NUP58	5846.0
VEGFA	5881.0
VPS11	5930.0
HSPG2	6016.0
RAB5A	6030.0
ZDHHC3	6056.0
AP2A1	6097.0
CHMP4B	6101.0
DAD1	6179.0
DUSP16	6196.0
MAPK3	6201.0
ST6GALNAC2	6296.0
CD79B	6306.0
NLRP12	6321.0
MGAT4B	6338.0
NCKIPSD	6388.0
RB1	6425.0
CHMP1A	6436.0
GPC2	6489.0
MAP2K2	6502.0
H4C4	6524.0
HMOX1	6570.0
PACS1	6572.0
H3C6	6602.0
IFNB1	6637.0
POLR2F	6656.0
IFNA13	6710.0
PML	6714.0
SNRPB	6751.0
AP1M1	6753.0
H2AC16	6777.0
GANAB	6785.0
CPSF4	6824.0
SMN1	6830.5
SMN2	6830.5
TYK2	6837.0
IFNA5	6924.0
VPS16	6931.0
CYFIP1	6938.0
IL17RA	6980.0
MAP2K4	6996.0
ENTPD5	7011.0
GNAT3	7017.0
RPL31	7031.0
ERCC2	7083.0
RPS3	7084.0
TKFC	7102.0
JAK2	7130.0
ANO1	7212.0
VPS4B	7242.0
CHD3	7250.0
ANO10	7257.0
IFNA8	7263.0
ST3GAL1	7283.0
MYO1C	7342.0
H4C12	7358.0
ATP1A3	7362.0
H2AC25	7365.0
RANBP2	7396.0
MBL2	7413.0
RPS27	7437.0
P2RX4	7454.0
CHUK	7456.0
NUP62	7457.0
DDOST	7512.0
RHBDF2	7519.0
CYFIP2	7531.0
RPL22	7534.0
MVB12B	7544.0
DVL3	7545.0
HDAC1	7551.0
GNG3	7617.0
CD4	7638.0
RELA	7644.0
RPS14	7712.0
RPS19	7721.0
POLR2A	7751.0
AP2M1	7773.0
VAMP2	7819.0
AKT1	7830.0
DVL1	7856.0
RCAN3	7865.0
FXYD6	7896.0
PARP1	8062.0
MTA3	8063.0
IFNA1	8075.0
AP2S1	8082.0
DOCK2	8104.0
PSMD3	8120.0
ITPR3	8146.0
MAN1B1	8182.0
ADCY5	8185.0
TUBAL3	8192.0
STAT2	8216.0
CTDP1	8234.0
TAB1	8248.0
H2BC3	8253.0
TUBB1	8278.0
RANGAP1	8373.0
HGS	8379.0
RNF213	8415.0
MAP2K7	8419.0
SEC13	8482.0
PDPK1	8583.0
NELFB	8624.0
GPC1	8651.0
ZDHHC8	8655.0
SRC	8731.0
MYO9B	8756.0
BRD4	8823.0
PRKAR1B	8839.0
SERPINE1	8901.0
DPEP3	8927.0
AP1B1	8936.0
BAIAP2	8966.0
SFN	8990.0
DPEP1	9010.0
DYNC1H1	9026.0
PLCG1	9033.0
CREBBP	9058.0
H3C3	9119.0
ANO7	9147.0
RIPK1	9165.0
H2BC10	9234.0
ST3GAL4	9277.0
SDC4	9285.0
SUZ12	9312.0
GNAZ	9473.0
VPS39	9522.0
CD28	9523.0
ADCY3	9563.0
H4C11	9599.0
ATP1A4	9631.0
AKT2	9642.0
RPL3L	9685.0
POLR2J	9748.0
TAF4	9763.0
PSMB11	9803.0
FXYD3	9832.0
MASP2	9841.0
H3C8	9880.0
MTA1	9928.0
CD8B	10039.0
GNGT1	10046.0
VAV2	10056.0
IFNA16	10109.0
GGT5	10137.0
TLR9	10162.0
SFTPD	10196.0
TUBA3D	10241.0
PRKACG	10288.0
ZBP1	10449.0
CD3G	10501.0
PDCD1	10506.0
PKLR	10533.0
GNB3	10726.0

---

REACTOME_CELLULAR_RESPONSE_TO_STARVATION

REACTOME_CELLULAR_RESPONSE_TO_STARVATION

	1582
set	REACTOME_CELLULAR_RESPONSE_TO_STARVATION
setSize	147
pANOVA	0.00156
s.dist	-0.151
p.adjustANOVA	0.0803

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL29	-10734
RPS12	-10480
ATP6V0E2	-10271
RPS25	-9996
RPL12	-9789
RPL23	-9573
CASTOR1	-9491
RPL18	-9396
ATP6V1B2	-9288
RPL10L	-9192
RPL13	-9165
RPL10A	-8981
RPS13	-8885
RPL24	-8697
RPS26	-8630
RPS6	-8578
RRAGC	-8538
RPL41	-8474
ATP6V1E1	-8322
RPS28	-8280

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL29	-10734.0
RPS12	-10480.0
ATP6V0E2	-10271.0
RPS25	-9996.0
RPL12	-9789.0
RPL23	-9573.0
CASTOR1	-9491.0
RPL18	-9396.0
ATP6V1B2	-9288.0
RPL10L	-9192.0
RPL13	-9165.0
RPL10A	-8981.0
RPS13	-8885.0
RPL24	-8697.0
RPS26	-8630.0
RPS6	-8578.0
RRAGC	-8538.0
RPL41	-8474.0
ATP6V1E1	-8322.0
RPS28	-8280.0
RPL13A	-8267.5
RPL14	-8156.0
RPL11	-8150.0
RPL4	-8026.0
RPL7	-8006.0
ITFG2	-7956.0
RPL39L	-7836.0
EIF2S1	-7708.0
FAU	-7687.0
RPL34	-7413.0
RRAGA	-7337.0
RPS15A	-7332.0
RPL5	-7169.0
SESN2	-6986.0
RPSA	-6914.0
RPL36AL	-6833.5
RPL37	-6752.0
ATF4	-6740.0
SLC38A9	-6703.0
RPLP0	-6587.0
EIF2S2	-6580.0
ATF3	-6537.0
RPL23A	-6481.0
RPL35A	-6473.0
RPL21	-6325.0
RPL22L1	-6284.0
RPS3A	-6158.0
RPL17	-5981.0
ATP6V1C1	-5753.0
RPL27A	-5715.0
RPS24	-5677.0
RPL18A	-5525.0
RPS18	-5357.0
RPL35	-5265.0
RPL8	-5017.0
RHEB	-4907.0
RPS20	-4837.0
RPLP2	-4592.0
FNIP2	-4561.0
UBA52	-4361.0
RPL28	-4300.0
RPS10	-4220.0
ATP6V1D	-4203.0
RPS11	-4189.0
ATP6V1G1	-4171.0
RPS5	-3903.0
RPL36	-3867.0
ASNS	-3531.0
RPLP1	-3490.0
RPL15	-3478.0
RPS29	-3289.0
RPL19	-3065.0
RPL9	-2640.0
RPS16	-2594.0
RPL30	-2386.0
FNIP1	-2372.0
RPS15	-2337.0
RPL6	-2141.0
ATP6V1F	-2015.0
LAMTOR5	-1886.0
KICS2	-1855.0
RPL3	-1846.0
DDIT3	-1681.0
RPS2	-1664.0
RPS27A	-1544.0
RPL38	-1357.0
RPS8	-1326.0
ATP6V1A	-1254.0
RPS23	-1205.0
RPL37A	-1087.0
RPS21	-811.0
ATP6V1H	-645.0
ATP6V0E1	-419.0
RPS9	-121.0
ATF2	-41.0
RPL32	63.0
BMT2	545.0
ATP6V0D2	1254.0
SH3BP4	1333.0
KPTN	1361.0
IMPACT	1415.0
DEPDC5	1679.0
RPS7	1873.0
ATP6V0C	1942.0
SEH1L	2049.0
ATP6V1C2	2355.0
RRAGD	2720.0
SESN1	2984.0
LAMTOR4	3035.0
CEBPG	3251.0
RPL26L1	3302.0
RPL27	3305.0
ATP6V1E2	3746.0
RPL26	3766.0
WDR59	3844.0
RPS27L	3876.0
NPRL2	4273.0
RPL7A	4313.0
MLST8	4747.0
LAMTOR2	5007.0
ATP6V1G2	5302.0
EIF2AK4	5421.0
MIOS	5959.0
CEBPB	6090.0
ATP6V1B1	6093.0
ATP6V1G3	6253.0
LAMTOR1	6612.0
LAMTOR3	6679.0
RPL31	7031.0
RPS3	7084.0
RPS27	7437.0
GCN1	7532.0
RPL22	7534.0
RPS14	7712.0
RPS19	7721.0
WDR24	7874.0
ATP6V0B	8105.0
SEC13	8482.0
MTOR	8691.0
NPRL3	8766.0
SZT2	8897.0
ATP6V0D1	9150.0
RPTOR	9243.0
FLCN	9674.0
RPL3L	9685.0
TCIRG1	9742.0
TRIB3	9868.0

---

REACTOME_COLLAGEN_FORMATION

REACTOME_COLLAGEN_FORMATION

	117
set	REACTOME_COLLAGEN_FORMATION
setSize	88
pANOVA	0.00184
s.dist	0.192
p.adjustANOVA	0.0913

Top enriched genes

Top 20 genes

GeneID	Gene Rank
P4HB	10390
COL6A2	10093
ITGB4	9977
BMP1	9750
COL27A1	9666
COL5A1	9262
COLGALT1	9121
PCOLCE	9016
P3H3	8832
CTSS	8394
COL10A1	8239
CTSB	8142
CD151	7990
COL13A1	7623
COL6A3	7272
LOXL1	7180
COL3A1	6950
COL11A2	6918
COL7A1	6704
COL17A1	6678

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
P4HB	10390
COL6A2	10093
ITGB4	9977
BMP1	9750
COL27A1	9666
COL5A1	9262
COLGALT1	9121
PCOLCE	9016
P3H3	8832
CTSS	8394
COL10A1	8239
CTSB	8142
CD151	7990
COL13A1	7623
COL6A3	7272
LOXL1	7180
COL3A1	6950
COL11A2	6918
COL7A1	6704
COL17A1	6678
LAMA3	6649
PXDN	6547
COL6A1	6522
SERPINH1	6482
COL9A2	6463
ADAMTS14	6010
ADAMTS2	5530
LOXL3	5477
PLOD1	5391
COL8A2	5294
MMP20	5200
P3H1	5195
LAMC2	5138
MMP7	5084
COL18A1	5041
COL6A6	4931
P4HA2	4476
COL4A2	4461
COL23A1	4342
P4HA3	4319
COL16A1	4080
LOXL4	3512
COL1A1	3142
PLOD3	3132
COL5A2	3027
PLEC	2917
COL15A1	2882
LOXL2	2750
COL11A1	2529
COL4A1	2436
COL22A1	2200
ITGA6	2165
COL26A1	2154
COL1A2	2152
COLGALT2	2114
CRTAP	1956
COL20A1	1231
COL21A1	962
LAMB3	-250
COL2A1	-389
COL28A1	-881
COL24A1	-1114
MMP9	-1485
TLL2	-2153
COL19A1	-2459
P4HA1	-2498
COL8A1	-2602
P3H2	-2953
DST	-3116
MMP3	-3522
CTSV	-4312
COL14A1	-4480
TLL1	-4553
COL9A3	-4628
ADAMTS3	-4982
PCOLCE2	-5209
PPIB	-5230
COL25A1	-5233
MMP13	-5242
COL9A1	-6330
COL5A3	-6711
COL6A5	-6792
COL12A1	-7347
COL4A3	-7747
COL4A4	-9050
PLOD2	-9802
LOX	-9857
CTSL	-10181

---

REACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS

REACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS

	973
set	REACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS
setSize	418
pANOVA	0.00191
s.dist	-0.0885
p.adjustANOVA	0.0922

Top enriched genes

Top 20 genes

GeneID	Gene Rank
AREG	-10988
HGF	-10497
HBEGF	-10493
ACTB	-10373
CD86	-10367
PHB1	-10328
EEF1G	-10100
BCL2A1	-10032
FGF20	-9972
KIT	-9851
RAP1A	-9737
UBB	-9702
PTPN11	-9664
PDGFB	-9654
NRG3	-9653
ETV6	-9583
TPM4	-9531
DKK2	-9505
PTPN12	-9456
BIN2	-9442

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
AREG	-10988
HGF	-10497
HBEGF	-10493
ACTB	-10373
CD86	-10367
PHB1	-10328
EEF1G	-10100
BCL2A1	-10032
FGF20	-9972
KIT	-9851
RAP1A	-9737
UBB	-9702
PTPN11	-9664
PDGFB	-9654
NRG3	-9653
ETV6	-9583
TPM4	-9531
DKK2	-9505
PTPN12	-9456
BIN2	-9442
PIK3R2	-9426
POLR2K	-9413
PSMC4	-9362
DKK1	-9219
ZC3HC1	-9206
NRAS	-9202
SKP1	-9156
HDAC9	-9141
APH1B	-9040
EREG	-9027
RHOG	-8996
PPM1B	-8864
PSMA8	-8792
FGF8	-8641
HEY1	-8626
RAC1	-8610
RPS6	-8578
TRAT1	-8549
ARRB2	-8483
TRIP11	-8447
SHH	-8429
APC	-8394
KAT2B	-8201
PDGFRA	-8199
STAT5A	-8197
SYVN1	-8178
ERLIN2	-8136
UBC	-7974
PSMD12	-7843
SHC1	-7816
FGF19	-7788
PIK3AP1	-7787
FOXO1	-7760
MAPK1	-7718
ACTG1	-7705
GTF2F1	-7689
FGFR1OP2	-7593
PSMB10	-7431
PSMC5	-7419
HES5	-7416
POLR2L	-7397
FGF3	-7376
FZD8	-7375
POLR2D	-7349
EPGN	-7315
LYN	-7312
FGF9	-7195
BCL11A	-7133
PSMB4	-7098
WNT3A	-7048
YES1	-6977
PEBP1	-6967
ERBB4	-6856
DUSP8	-6851
NPM1	-6785
PRKAR1A	-6767
HES1	-6760
PSME4	-6754
LMNA	-6732
KIF5B	-6693
IHH	-6653
HDAC2	-6547
POLR2I	-6513
JAG1	-6475
KL	-6471
FGF23	-6468
GAB1	-6416
FGF10	-6358
SNW1	-6319
DUSP10	-6297
CASP9	-6274
AGTRAP	-6244
GAB2	-6223
PSMC2	-6092
PSME2	-6084
SMAD4	-6076
HSP90AA1	-6002
PSMA3	-5986
ERLEC1	-5913
AGK	-5862
PSMB8	-5844
MAML1	-5839
ALK	-5833
TGFA	-5777
GCC2	-5767
PIK3R1	-5752
ICOS	-5737
ESRP1	-5612
MRAS	-5540
NRG1	-5528
ATIC	-5501
EIF2AK3	-5491
MET	-5427
EGF	-5404
LRRFIP1	-5326
FAM114A2	-5317
KDR	-5228
NCBP2	-5148
SPRED1	-5145
OS9	-5097
FYN	-5019
FGA	-4994
APH1A	-4917
GOLGA4	-4878
KITLG	-4853
EML4	-4814
ADAM17	-4731
BCL2L11	-4681
DERL2	-4661
SMAD3	-4614
PSEN2	-4610
CLTC	-4494
NRG4	-4442
AKT1S1	-4441
PSMA5	-4438
CUL1	-4436
FGF17	-4415
UBA52	-4361
CSNK1A1	-4349
PSMD11	-4325
PPP2R5B	-4264
PSMD5	-4244
PPP2CB	-4240
FGF5	-4107
PIM1	-4091
PPP2R5E	-4074
DHH	-4051
BTC	-4048
GOLGB1	-4010
TGFBR1	-3993
PSMD9	-3987
FZD4	-3972
BAG4	-3965
POLR2C	-3916
LCK	-3915
SPRED3	-3894
RBPJ	-3875
PTEN	-3849
MYC	-3827
ZC3HAV1	-3749
TNKS2	-3719
TPM3	-3630
BRAP	-3548
BCL2L1	-3491
JUNB	-3457
FLT3	-3438
PSMA6	-3425
KREMEN2	-3286
ESR2	-3242
PIK3R3	-3209
HHAT	-3202
RBX1	-3122
DUSP6	-3092
PSMC1	-3076
HDAC11	-3067
PSME3	-3024
KREMEN1	-2992
GRB2	-2984
GSK3B	-2980
PSMB9	-2972
APBB1IP	-2956
MAML2	-2936
BRAF	-2758
PPFIBP1	-2676
EGFR	-2625
CREB1	-2614
HDAC10	-2600
STAT3	-2557
NCSTN	-2437
PPP2CA	-2430
STAT5B	-2385
FGF1	-2378
BAD	-2325
VWF	-2315
KDM7A	-2283
CNKSR1	-2198
PSMD1	-2120
PSENEN	-1995
TGFBR2	-1959
NOX4	-1843
PSMB5	-1772
FZD6	-1765
SQSTM1	-1672
VCP	-1618
NF1	-1570
PSMA1	-1545
RPS27A	-1544
FGF7	-1520
MAML3	-1443
MDM2	-1436
KRAS	-1382
PSMB3	-1361
TFG	-1341
ARRB1	-1279
PSEN1	-1262
SPTBN1	-1240
FZD5	-1170
MIB2	-1110
RAP1B	-1070
FGF4	-1054
FKBP1A	-1001
MARK3	-843
CSK	-783
TRIM24	-722
PIK3CA	-717
PSME1	-658
CLCN6	-584
GTF2F2	-573
PAPSS1	-489
VAV1	-400
CPSF6	-390
NCBP1	-381
PPP2R5A	-380
YWHAB	-355
STAT1	-317
KSR2	-282
DUSP7	-261
WDR48	-197
FXR1	-174
KANK1	-137
TBL1XR1	-134
FBXW7	-88
SEM1	-1
PRR5	29
CAMK2D	77
POLR2B	117
CEP43	154
HIP1	177
SEL1L	200
ITGB3	248
PSMD8	315
MAP2K1	378
QKI	448
NEURL1B	468
FIP1L1	484
KIAA1549	510
CBL	556
CDKN1A	606
KSR1	751
EP300	781
RAC2	892
IRS1	893
POLR2G	936
PSMA7	942
ZMYM2	948
SHOC2	1006
PSMA2	1059
TCF7L2	1128
PSMD7	1158
FGB	1189
PPP1CB	1209
PPP2R1A	1222
ADAM10	1278
TNKS	1402
WDCP	1403
LRP6	1449
PSMB2	1566
PPP2R5C	1594
GSK3A	1699
TENT4A	1736
MIB1	1746
HDAC3	1872
NCOR1	1885
FRS3	1924
FGG	2001
CDKN1B	2040
POLR2E	2087
PIK3CD	2150
ERBB2	2158
FGFR1	2177
CAMK2G	2220
DLL1	2367
PSMD14	2369
BCR	2476
PPP1CC	2600
RPS6KB2	2636
PDGFA	2732
PSMC3	2777
POLR2H	2784
MAP3K11	2913
ITGA2B	2935
ZFYVE9	2948
STRN	3025
SPRED2	3046
FOXO3	3101
TRAK1	3192
FN1	3290
PSMD13	3304
SOS1	3385
CTNNB1	3514
HDAC7	3545
TPR	3550
PSMB7	3558
PSMD4	3642
PSMD2	3699
TGFB1	3769
CALM1	3777
AKT3	3841
AKAP9	3919
CDK8	3969
AP3B1	4003
MAPKAP1	4030
PSMA4	4073
HDAC5	4084
BIRC6	4138
SMAD2	4309
PSMC6	4442
PSMD6	4479
ESR1	4621
CAMK2A	4700
ERBB3	4703
MLST8	4747
IRS2	4801
IQGAP1	4824
FGFR2	4834
AXIN1	4866
FLT3LG	4867
SND1	4876
NEURL1	4900
NCOR2	4914
ATG7	4944
VCL	4950
LMO7	5057
SEC31A	5082
PSMB6	5196
PSMF1	5201
PPP2R5D	5283
RRBP1	5352
PSMB1	5414
ERBIN	5445
MYH9	5470
FGF2	5483
CUX1	5561
NRG2	5631
AGGF1	5721
NR4A1	5829
FRS2	6075
CEBPB	6090
CD80	6145
CCNC	6191
DUSP16	6196
MAPK3	6201
RAF1	6216
DLL4	6259
HEY2	6398
MAP2K2	6502
FAM131B	6523
DKK4	6630
POLR2F	6656
RICTOR	6796
NOTCH1	6821
PIK3CB	6910
LRP5	6952
DCTN1	7044
MYO18A	7115
JAK2	7130
RANBP2	7396
CHUK	7456
KLB	7467
JAG2	7491
CD19	7530
HDAC1	7551
FGF22	7577
CTBP2	7591
POLR2A	7751
AKT1	7830
TLN1	7849
KAT2A	8115
PSMD3	8120
CNTRL	8157
PDGFRB	8213
FGF18	8225
CDC37	8302
CAMK2B	8374
RNF213	8415
HRAS	8450
KLC1	8547
PDPK1	8583
CTBP1	8609
MTOR	8691
SRC	8731
FGF6	8910
PPP2R1B	8914
PLCG1	9033
CREBBP	9058
FGFR3	9212
CARS1	9358
RNF43	9416
TSC2	9448
CD28	9523
FGFR4	9541
HDAC4	9605
AKT2	9642
HEYL	9678
POLR2J	9748
PSMB11	9803
MPRIP	9866
FOXO6	10462

---

REACTOME_SARS_COV_1_INFECTION

REACTOME_SARS_COV_1_INFECTION

	1539
set	REACTOME_SARS_COV_1_INFECTION
setSize	136
pANOVA	0.00221
s.dist	-0.152
p.adjustANOVA	0.104

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PYCARD	-10974
RPS12	-10480
CHMP4C	-10227
ZCRB1	-10186
CTSL	-10181
BST2	-10179
RPS25	-9996
UBB	-9702
SUMO1	-9697
STING1	-9618
YWHAE	-9457
TBK1	-9043
NFKBIA	-8939
TMPRSS2	-8937
RPS13	-8885
RPS26	-8630
RPS6	-8578
HNRNPA1	-8516
RPS28	-8280
NLRP3	-8233

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PYCARD	-10974
RPS12	-10480
CHMP4C	-10227
ZCRB1	-10186
CTSL	-10181
BST2	-10179
RPS25	-9996
UBB	-9702
SUMO1	-9697
STING1	-9618
YWHAE	-9457
TBK1	-9043
NFKBIA	-8939
TMPRSS2	-8937
RPS13	-8885
RPS26	-8630
RPS6	-8578
HNRNPA1	-8516
RPS28	-8280
NLRP3	-8233
TOMM70	-8001
UBC	-7974
PIK3C3	-7928
FAU	-7687
MAP1LC3B	-7452
RPS15A	-7332
MOGS	-7322
IRAK2	-7144
CHMP2B	-7022
YWHAH	-6931
RPSA	-6914
IFIH1	-6817
NPM1	-6785
YWHAZ	-6541
RPS3A	-6158
SMAD4	-6076
KPNA2	-5929
KPNB1	-5688
RPS24	-5677
CANX	-5437
RPS18	-5357
PPIB	-5230
NMI	-4937
YWHAQ	-4922
RPS20	-4837
SMAD3	-4614
EEF1A1	-4419
UBA52	-4361
BECN1	-4342
RPS10	-4220
RPS11	-4189
CASP1	-4103
PCBP2	-4088
PARP4	-3969
RPS5	-3903
RUNX1	-3889
BCL2L1	-3491
CHMP7	-3302
RPS29	-3289
NFKB1	-3211
GSK3B	-2980
PALS1	-2731
DDX5	-2682
PPIH	-2611
RPS16	-2594
SP1	-2592
RPS15	-2337
PRKCSH	-2092
SIKE1	-2034
MGAT1	-1806
MAVS	-1768
RPS2	-1664
YWHAG	-1652
VCP	-1618
CHMP2A	-1612
RPS27A	-1544
VHL	-1534
CAV1	-1489
PPIG	-1334
RPS8	-1326
RPS23	-1205
FKBP1A	-1001
TRIM25	-816
RPS21	-811
RIPK3	-810
ST3GAL3	-760
YWHAB	-355
GALNT1	-209
TRAF6	-191
RPS9	-121
IRF3	23
UVRAG	479
CHMP6	719
EP300	781
CHMP3	1027
ST6GALNAC4	1052
PARP8	1136
PARP10	1434
CHMP4A	1628
GSK3A	1699
RPS7	1873
UBE2I	2333
PIK3R4	2389
ST3GAL2	2774
PARP9	2789
IKBKE	3105
RIGI	3277
PARP16	3579
ST6GALNAC3	3797
RPS27L	3876
ITCH	3965
TRAF3	4031
PSMC6	4442
PARP14	4793
PARP6	5001
PPIA	5114
ST6GAL1	5626
CHMP4B	6101
ST6GALNAC2	6296
RB1	6425
GANAB	6785
RPS3	7084
TKFC	7102
ST3GAL1	7283
RPS27	7437
RELA	7644
RPS14	7712
RPS19	7721
RCAN3	7865
PDPK1	8583
SERPINE1	8901
SFN	8990
RIPK1	9165
ST3GAL4	9277
SFTPD	10196
PKLR	10533

---

REACTOME_ACTIVATION_OF_THE_PHOTOTRANSDUCTION_CASCADE

REACTOME_ACTIVATION_OF_THE_PHOTOTRANSDUCTION_CASCADE

	495
set	REACTOME_ACTIVATION_OF_THE_PHOTOTRANSDUCTION_CASCADE
setSize	11
pANOVA	0.00283
s.dist	0.52
p.adjustANOVA	0.129

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PDE6G	10662
GNGT1	10046
PDE6B	9851
RHO	9068
SAG	8311
CNGA1	5645
CNGB1	4460
GNB1	3778
SLC24A1	3649
GNAT1	1311
PDE6A	-4428

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PDE6G	10662
GNGT1	10046
PDE6B	9851
RHO	9068
SAG	8311
CNGA1	5645
CNGB1	4460
GNB1	3778
SLC24A1	3649
GNAT1	1311
PDE6A	-4428

---

REACTOME_INTERLEUKIN_1_FAMILY_SIGNALING

REACTOME_INTERLEUKIN_1_FAMILY_SIGNALING

	792
set	REACTOME_INTERLEUKIN_1_FAMILY_SIGNALING
setSize	146
pANOVA	0.00296
s.dist	-0.142
p.adjustANOVA	0.132

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PTPN7	-10824
CTSG	-10743
IL13	-10645
IL1B	-10551
IRAK3	-10511
TIFA	-10144
IL18RAP	-9965
UBB	-9702
PTPN11	-9664
PTPN12	-9456
PSMC4	-9362
IL1R2	-9287
SKP1	-9156
CASP8	-9058
TBK1	-9043
IL33	-8961
NFKBIA	-8939
S100A12	-8914
PSMA8	-8792
NOD2	-8386

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PTPN7	-10824
CTSG	-10743
IL13	-10645
IL1B	-10551
IRAK3	-10511
TIFA	-10144
IL18RAP	-9965
UBB	-9702
PTPN11	-9664
PTPN12	-9456
PSMC4	-9362
IL1R2	-9287
SKP1	-9156
CASP8	-9058
TBK1	-9043
IL33	-8961
NFKBIA	-8939
S100A12	-8914
PSMA8	-8792
NOD2	-8386
SIGIRR	-8358
UBE2V1	-8226
UBE2N	-8206
UBC	-7974
PSMD12	-7843
SAA1	-7546
IL18	-7504
PSMB10	-7431
PSMC5	-7419
MAP3K8	-7243
IRAK2	-7144
PELI3	-7104
PSMB4	-7098
PSME4	-6754
IL36G	-6688
IL1RL1	-6648
IL1R1	-6603
PSMC2	-6092
PSME2	-6084
PSMA3	-5986
USP18	-5857
PSMB8	-5844
HMGB1	-5679
FBXW11	-5451
IL1RAP	-5368
MAP3K7	-5328
SMAD3	-4614
PTPN13	-4488
PSMA5	-4438
CUL1	-4436
UBA52	-4361
PSMD11	-4325
PSMD5	-4244
NKIRAS2	-4199
CASP1	-4103
PSMD9	-3987
PTPN6	-3922
TNIP2	-3790
ALOX5	-3720
PTPN18	-3557
PSMA6	-3425
IRAK4	-3272
NFKB1	-3211
IKBIP	-3187
RBX1	-3122
APP	-3117
MYD88	-3102
PSMC1	-3076
PSME3	-3024
PSMB9	-2972
PELI2	-2762
PTPN2	-2727
USP14	-2709
PTPN9	-2696
NFKBIB	-2561
STAT3	-2557
PSMD1	-2120
PSMB5	-1772
NOD1	-1677
SQSTM1	-1672
PSMA1	-1545
RPS27A	-1544
NKIRAS1	-1504
TAB2	-1440
PSMB3	-1361
MAP3K3	-1296
TP53	-1167
PSME1	-658
TRAF6	-191
SEM1	-1
NFKB2	109
PSMD8	315
IL1RL2	350
MAP2K1	378
BTRC	810
PSMA7	942
PSMA2	1059
MAP2K6	1098
PSMD7	1158
IL1A	1307
PSMB2	1566
IL1RN	1911
GSDMD	1972
PSMD14	2369
TRAF2	2552
PELI1	2717
N4BP1	2722
PSMC3	2777
IL36B	2975
IL36A	3203
PSMD13	3304
MAPK8	3348
PSMB7	3558
PSMD4	3642
PSMD2	3699
PTPN23	3802
PSMA4	4073
IKBKB	4370
PSMC6	4442
IL18R1	4451
PSMD6	4479
PTPN14	4491
RIPK2	4589
PSMB6	5196
PSMF1	5201
LRRC14	5202
PSMB1	5414
NLRX1	6433
ALPK1	6923
MAP2K4	6996
IL37	7007
CHUK	7456
PTPN4	7596
RELA	7644
TOLLIP	7660
S100B	7729
IL1F10	8014
NLRC5	8083
PSMD3	8120
IL4	8170
TAB1	8248
AGER	8360
PTPN5	9036
IL36RN	9745
PSMB11	9803
IL18BP	10172

---

REACTOME_NUCLEAR_EVENTS_STIMULATED_BY_ALK_SIGNALING_IN_CANCER

REACTOME_NUCLEAR_EVENTS_STIMULATED_BY_ALK_SIGNALING_IN_CANCER

	1587
set	REACTOME_NUCLEAR_EVENTS_STIMULATED_BY_ALK_SIGNALING_IN_CANCER
setSize	18
pANOVA	0.00352
s.dist	-0.397
p.adjustANOVA	0.147

Top enriched genes

Top 20 genes

GeneID	Gene Rank
BCL2A1	-10032
ZC3HC1	-9206
SKP1	-9156
RPS6	-8578
STAT5A	-8197
MAPK1	-7718
NPM1	-6785
KIF5B	-6693
ALK	-5833
EML4	-4814
CLTC	-4494
CUL1	-4436
JUNB	-3457
RBX1	-3122
STAT3	-2557
FN1	3290
CEBPB	6090
MAPK3	6201

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
BCL2A1	-10032
ZC3HC1	-9206
SKP1	-9156
RPS6	-8578
STAT5A	-8197
MAPK1	-7718
NPM1	-6785
KIF5B	-6693
ALK	-5833
EML4	-4814
CLTC	-4494
CUL1	-4436
JUNB	-3457
RBX1	-3122
STAT3	-2557
FN1	3290
CEBPB	6090
MAPK3	6201

---

REACTOME_NEUTROPHIL_DEGRANULATION

REACTOME_NEUTROPHIL_DEGRANULATION

	1053
set	REACTOME_NEUTROPHIL_DEGRANULATION
setSize	460
pANOVA	0.00357
s.dist	-0.0793
p.adjustANOVA	0.147

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TYROBP	-11000
PYCARD	-10974
FOLR3	-10965
RNASE3	-10959
MPO	-10919
ORM1	-10916
AZU1	-10898
FGR	-10840
CD177	-10796
B4GALT1	-10778
PRTN3	-10766
CTSG	-10743
MS4A3	-10562
CEACAM6	-10557
AGPAT2	-10520
CEACAM3	-10436
FPR2	-10404
SLPI	-10403
PLEKHO2	-10334
HEBP2	-10287

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TYROBP	-11000
PYCARD	-10974
FOLR3	-10965
RNASE3	-10959
MPO	-10919
ORM1	-10916
AZU1	-10898
FGR	-10840
CD177	-10796
B4GALT1	-10778
PRTN3	-10766
CTSG	-10743
MS4A3	-10562
CEACAM6	-10557
AGPAT2	-10520
CEACAM3	-10436
FPR2	-10404
SLPI	-10403
PLEKHO2	-10334
HEBP2	-10287
CD63	-10282
PRDX6	-10239
BST2	-10179
RAB27A	-10161
STBD1	-10068
VAT1	-10065
NDUFC2	-10036
HSPA1A	-9954
MME	-9945
CD33	-9911
CTSZ	-9893
ILF2	-9864
CPNE3	-9854
TBC1D10C	-9849
OSTF1	-9801
TICAM2	-9788
GLIPR1	-9747
HSPA1B	-9743
SERPINB1	-9739
RAP1A	-9737
CXCL1	-9709
RAB3D	-9672
CTSD	-9665
PPBP	-9638
STING1	-9618
FTL	-9580
HSPA8	-9533
GMFG	-9525
TMEM30A	-9511
BIN2	-9442
B2M	-9228
CD68	-9221
TMEM179B	-9212
TARM1	-9204
NRAS	-9202
ATP6V0A1	-9055
RHOG	-8996
S100A12	-8914
UNC13D	-8905
STOM	-8904
CFD	-8891
BRI3	-8824
TMBIM1	-8795
TMC6	-8793
OLR1	-8670
CD14	-8611
RAC1	-8610
TUBB4B	-8604
HP	-8533
COMMD3	-8517
CDA	-8495
DEFA4	-8452
GYG1	-8450
TUBB	-8449
S100A8	-8349
HBB	-8277
FCGR3B	-8230
SNAP29	-8138
GDI2	-8131
CD300A	-8106
PLAU	-8031
TCN1	-8007
P2RX1	-7942
FTH1	-7920
PLAC8	-7850
RAP2B	-7844
PSMD12	-7843
PGAM1	-7791
PGM2	-7742
MAPK1	-7718
SNAP23	-7715
CR1	-7714
CD55	-7710
ELANE	-7685
DSN1	-7562
MGST1	-7525
SVIP	-7463
ENPP4	-7448
CTSC	-7436
CLEC12A	-7216
LAIR1	-7085
SIGLEC5	-7023
CD59	-6877
HSP90AB1	-6813
CLEC5A	-6654
CD58	-6563
SURF4	-6524
SELL	-6407
IQGAP2	-6264
MAPK14	-6253
IDH1	-6229
CTSA	-6212
FABP5	-6211
TNFAIP6	-6156
RAB31	-6141
GPR84	-6093
PSMC2	-6092
CAND1	-6062
PLD1	-6055
PTPRC	-6035
HGSNAT	-6015
HSP90AA1	-6002
CDK13	-5894
CYB5R3	-5740
PGLYRP1	-5709
KPNB1	-5688
HMGB1	-5679
BPI	-5577
RAB10	-5576
ACTR10	-5559
FCER1G	-5416
ERP44	-5387
LRG1	-5273
NHLRC3	-5269
ASAH1	-5187
CNN2	-5172
SLC27A2	-5171
SLC15A4	-5149
OSCAR	-5015
SRP14	-4955
PA2G4	-4948
STK11IP	-4938
ACTR2	-4881
MIF	-4836
GRN	-4819
NPC2	-4745
HLA-B	-4701
RAB14	-4572
KCMF1	-4528
SCAMP1	-4482
PRCP	-4459
PSMA5	-4438
EEF1A1	-4419
RAB37	-4408
NME2	-4359
S100A7	-4344
PTX3	-4332
PSMD11	-4325
PGM1	-4322
PAFAH1B2	-4319
IMPDH1	-4285
ATP6V1D	-4203
CSTB	-4183
CRISPLD2	-4112
HLA-A	-4075
SDCBP	-4069
RETN	-4043
ARPC5	-4011
PTPN6	-3922
DYNLT1	-3917
ARMC8	-3892
GCA	-3866
ALDH3B1	-3805
PTPRB	-3772
APRT	-3762
PTPRJ	-3725
ALOX5	-3720
SYNGR1	-3682
S100A9	-3635
DEGS1	-3628
NCKAP1L	-3603
SERPINB3	-3578
FUCA1	-3564
YPEL5	-3493
DSP	-3433
DNAJC13	-3414
RAB24	-3380
ADGRE3	-3339
RAB6A	-3224
NFKB1	-3211
GGH	-3154
GNS	-2916
CEP290	-2898
DYNLL1	-2813
SLC2A3	-2778
NIT2	-2655
RHOF	-2467
NCSTN	-2437
IRAG2	-2252
HK3	-2246
TIMP2	-2222
CCT2	-2164
PRSS3	-2139
PSMD1	-2120
CCT8	-1952
DSG1	-1889
ATP8A1	-1816
FPR1	-1811
LILRA3	-1808
PSAP	-1802
CD44	-1715
MMP8	-1704
XRCC6	-1669
VCP	-1618
CSNK2B	-1533
MMP9	-1485
XRCC5	-1476
TLR2	-1428
CD47	-1418
MANBA	-1393
RAB3A	-1300
PDAP1	-1290
LILRB2	-1284
GHDC	-1267
PSEN1	-1262
VAPA	-1190
CD93	-1169
SERPINA3	-1142
RAB5B	-1135
SLC11A1	-1121
RAP1B	-1070
ROCK1	-1011
SLCO4C1	-965
ATP8B4	-826
C5AR1	-817
SERPINB10	-803
GOLGA7	-674
CXCR2	-642
TRAPPC1	-630
CD36	-543
C3AR1	-468
HEXB	-467
TMEM63A	-459
IST1	-439
FUCA2	-370
LTF	-341
SLC44A2	-331
APAF1	-322
ORM2	-204
KRT1	-182
LTA4H	-146
CTSH	-95
CST3	-34
CYBA	64
PECAM1	82
HPSE	155
LYZ	292
ADGRG3	399
JUP	578
PRKCD	639
CHIT1	687
FRK	777
GLB1	792
PLAUR	971
AOC1	1008
LRRC7	1022
PADI2	1038
ITGAM	1055
GM2A	1057
PSMA2	1059
CPPED1	1148
PSMD7	1158
OLFM4	1200
GSTP1	1223
DYNC1LI1	1261
COMMD9	1275
ADAM10	1278
TXNDC5	1340
AMPD3	1343
CAPN1	1356
RAB7A	1376
FCAR	1424
BST1	1460
ARHGAP9	1588
ARSB	1595
MCEMP1	1597
QPCT	1624
HLA-C	1645
RHOA	1702
DIAPH1	1732
C1orf35	1802
PNP	1934
ATP6V0C	1942
GSDMD	1972
MAN2B1	2003
DERA	2053
CYSTM1	2077
AGA	2103
MVP	2136
ALDOA	2190
ORMDL3	2313
ANO6	2315
ARSA	2362
PSMD14	2369
PKM	2420
ABCA13	2463
S100P	2562
ADGRE5	2581
VNN1	2605
ARG1	2628
CXCR1	2708
CAP1	2748
PYGL	2776
PSMC3	2777
TSPAN14	2791
ITGB2	2817
ACLY	2846
SIGLEC14	2871
ALAD	2921
TNFRSF1B	2930
STK10	2939
RNASE2	2974
PTAFR	3097
ACP3	3144
ITGAL	3181
PSMD13	3304
HVCN1	3320
C3	3375
MGAM	3381
PSMB7	3558
C6orf120	3570
CRACR2A	3602
PSMD2	3699
CMTM6	3702
VAMP8	3770
COPB1	3834
MNDA	3886
GSN	3907
ITGAX	3938
TTR	3955
CD53	4004
RNASET2	4097
ATAD3B	4106
CKAP4	4122
HRNR	4145
ATP11B	4214
PTPRN2	4257
FAF2	4269
SIRPA	4294
NFAM1	4448
FCGR2A	4453
TRPM2	4465
PSMD6	4479
ADAM8	4779
IQGAP1	4824
ATG7	4944
CAT	4947
VCL	4950
IGF2R	4957
AP2A2	4969
CAB39	4978
SERPINB12	4990
LAMTOR2	5007
PPIA	5114
VPS35L	5179
GPI	5203
S100A11	5224
SLC2A5	5244
CANT1	5319
AGL	5329
CREG1	5385
RAB5C	5408
PSMB1	5414
CEACAM8	5558
CAMP	5602
SNAP25	5636
HMOX2	5676
DNAJC3	5724
IMPDH2	5742
RAB4B	5766
EEF2	5833
ANXA2	5910
NEU1	6199
ADA2	6257
CPNE1	6392
ITGAV	6399
DNAJC5	6554
LAMTOR1	6612
LAMTOR3	6679
AP1M1	6753
PPIE	6772
ANPEP	6794
PDXK	6833
UBR4	6878
SIGLEC9	6884
CYFIP1	6938
PKP1	6973
SERPINB6	7046
ALDOC	7063
PIGR	7170
LILRB3	7182
NFASC	7207
TOM1	7299
RAB18	7374
PRG3	7392
ACTR1B	7503
DDOST	7512
DPP7	7516
LAMP1	7541
TOLLIP	7660
CHI3L1	7670
QSOX1	7693
DBNL	7728
CHRNB4	7776
HSPA6	7793
PTGES2	7967
MMP25	8051
MLEC	8067
LGALS3	8085
SERPINA1	8101
DOCK2	8104
PSMD3	8120
CTSB	8142
SPTAN1	8195
DOK3	8382
CTSS	8394
ARHGAP45	8432
SIRPB1	8561
COTL1	8605
CLEC4D	8704
PFKL	8763
AHSG	8810
PYGB	8818
LPCAT1	8866
ACAA1	8902
FLG2	8912
FGL2	8922
GUSB	8973
ARL8A	8991
DYNC1H1	9026
NBEAL2	9031
ATP11A	9217
A1BG	9252
CRISP3	9303
KCNAB2	9306
CLEC4C	9403
NAPRT	9433
RAB44	9723
CEACAM1	9732
TCIRG1	9742
GAA	9823
LCN2	9859
APEH	9887
PRG2	9922
DGAT1	9960
FCN1	9969
GALNS	10173
CALML5	10611
DSC1	10741
EPX	10849

---

REACTOME_DNA_REPLICATION

REACTOME_DNA_REPLICATION

	1113
set	REACTOME_DNA_REPLICATION
setSize	178
pANOVA	0.00359
s.dist	-0.127
p.adjustANOVA	0.147

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC20	-10322
RPA2	-9888
UBB	-9702
H2AX	-9652
UBE2C	-9598
CCNE2	-9594
CDC16	-9479
H4C8	-9377
PSMC4	-9362
RFC4	-9330
SKP1	-9156
POLE4	-9123
H3-3A	-9072
H2BC21	-9064
CCNA1	-9044
PRIM2	-9003
POLD4	-8975
H2BC5	-8892
PSMA8	-8792
H4C3	-8439

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC20	-10322.0
RPA2	-9888.0
UBB	-9702.0
H2AX	-9652.0
UBE2C	-9598.0
CCNE2	-9594.0
CDC16	-9479.0
H4C8	-9377.0
PSMC4	-9362.0
RFC4	-9330.0
SKP1	-9156.0
POLE4	-9123.0
H3-3A	-9072.0
H2BC21	-9064.0
CCNA1	-9044.0
PRIM2	-9003.0
POLD4	-8975.0
H2BC5	-8892.0
PSMA8	-8792.0
H4C3	-8439.0
FEN1	-8359.0
H3C10	-7994.0
POLE3	-7984.0
UBC	-7974.0
ANAPC10	-7909.0
H2BC11	-7869.0
PSMD12	-7843.0
H2BC14	-7552.0
PSMB10	-7431.0
PSMC5	-7419.0
ANAPC16	-7276.0
H2BC17	-7263.0
PSMB4	-7098.0
H2BC4	-7072.0
H3-3B	-6937.0
H3C2	-6790.0
PSME4	-6754.0
H2AJ	-6672.0
H2BC13	-6590.0
H2AC8	-6445.0
H2AC7	-6250.5
H2BC7	-6250.5
H2AC6	-6100.0
PSMC2	-6092.0
PSME2	-6084.0
CDK2	-6001.0
UBE2E1	-5994.0
H2BC8	-5989.0
PSMA3	-5986.0
PSMB8	-5844.0
CCNA2	-5784.0
H2AC18	-5704.5
H2AC19	-5704.5
KPNB1	-5688.0
H3C4	-5557.0
MCM5	-5534.0
CDC6	-5492.0
H2AC14	-5481.0
DBF4	-5196.0
PRIM1	-5166.0
GINS1	-5164.0
H3C12	-5090.0
PSMA5	-4438.0
CUL1	-4436.0
UBA52	-4361.0
KPNA1	-4347.0
PSMD11	-4325.0
PSMD5	-4244.0
H2BC6	-4207.0
H4C6	-4120.0
CDC26	-4109.0
PSMD9	-3987.0
GINS4	-3981.0
POLA2	-3850.0
H3C11	-3817.0
UBE2S	-3726.0
SKP2	-3685.0
MCM8	-3684.0
MCM3	-3680.0
CDC23	-3430.0
PSMA6	-3425.0
RBX1	-3122.0
H4C13	-3097.0
PSMC1	-3076.0
PSME3	-3024.0
PSMB9	-2972.0
ORC6	-2939.0
MCM4	-2549.0
ORC4	-2392.0
H2AZ2	-2221.0
ANAPC1	-2192.0
PSMD1	-2120.0
PSMB5	-1772.0
PSMA1	-1545.0
RPS27A	-1544.0
H2AZ1	-1527.0
PSMB3	-1361.0
H4C2	-1183.0
ORC3	-1149.0
CDC7	-952.0
H4C1	-737.0
PSME1	-658.0
PCNA	-634.0
CCNE1	-622.0
H4C5	-618.0
RFC2	-527.0
ORC5	-511.0
H2BC15	-371.0
GMNN	-187.0
H2BC1	-54.0
SEM1	-1.0
PSMD8	315.0
H2BC12	672.0
PSMA7	942.0
POLD2	996.0
ANAPC7	1021.0
PSMA2	1059.0
PSMD7	1158.0
PSMB2	1566.0
RFC1	2250.0
RFC5	2266.0
ORC2	2350.0
PSMD14	2369.0
MCM10	2576.0
GINS2	2658.0
PSMC3	2777.0
H2AC4	2947.0
RPA3	3162.0
RFC3	3245.0
H4C16	3253.0
ANAPC11	3289.0
PSMD13	3304.0
ANAPC5	3520.0
PSMB7	3558.0
MCM2	3583.0
PSMD4	3642.0
PSMD2	3699.0
POLE2	3905.0
PSMA4	4073.0
H3C1	4262.0
PSMC6	4442.0
FZR1	4472.0
PSMD6	4479.0
H2BC26	4643.0
UBE2D1	4660.0
KPNA6	4929.0
ANAPC15	5002.0
ANAPC4	5089.0
RPA1	5108.0
PSMB6	5196.0
PSMF1	5201.0
H4C9	5218.0
H2BC9	5307.5
H3C7	5307.5
PSMB1	5414.0
LIG1	5744.0
CDC27	6028.0
POLD3	6096.0
MCM7	6480.0
MCM6	6501.0
H4C4	6524.0
H3C6	6602.0
GINS3	6729.0
ORC1	6741.0
DNA2	6788.0
H4C12	7358.0
CDC45	7641.0
ANAPC2	7945.0
PSMD3	8120.0
POLD1	8164.0
H2BC3	8253.0
POLE	8606.0
H3C3	9119.0
H2BC10	9234.0
CDT1	9353.0
H4C11	9599.0
PSMB11	9803.0
H3C8	9880.0

---

REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

	1161
set	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION
setSize	1336
pANOVA	0.00388
s.dist	-0.0471
p.adjustANOVA	0.155

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ZNF658	-11001
FASLG	-10891
MIR24-2	-10861
BGLAP	-10827
ZNF676	-10789
MIR27A	-10780
ZNF732	-10762
ZNF677	-10729
NFE2	-10684
GP1BA	-10671
NKX3-2	-10621
ZNF320	-10585
GPS2	-10539
COX14	-10527
NLRC4	-10434
IL3	-10344
THOC3	-10330
GATA2	-10325
H2AC20	-10322
ZNF625	-10295

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ZNF658	-11001.0
FASLG	-10891.0
MIR24-2	-10861.0
BGLAP	-10827.0
ZNF676	-10789.0
MIR27A	-10780.0
ZNF732	-10762.0
ZNF677	-10729.0
NFE2	-10684.0
GP1BA	-10671.0
NKX3-2	-10621.0
ZNF320	-10585.0
GPS2	-10539.0
COX14	-10527.0
NLRC4	-10434.0
IL3	-10344.0
THOC3	-10330.0
GATA2	-10325.0
H2AC20	-10322.0
ZNF625	-10295.0
SOD2	-10290.0
ZNF790	-10261.0
ZNF620	-10184.0
CTSL	-10181.0
MED20	-10176.0
ELF1	-10159.0
RORB	-10123.0
KMT5A	-10089.0
RBL1	-10021.0
ZNF521	-10016.0
ZNF440	-9971.0
ZNF479	-9956.0
NR1H3	-9925.0
RPA2	-9888.0
MAGOH	-9876.0
CLP1	-9852.0
KIT	-9851.0
ZNF729	-9806.0
ZNF429	-9757.0
GADD45A	-9751.0
PRKAA2	-9730.0
ZNF175	-9720.0
UBB	-9702.0
TTC5	-9698.0
SUMO1	-9697.0
TNFRSF10C	-9689.0
PTPN11	-9664.0
H2AX	-9652.0
ZNF561	-9637.0
ZNF614	-9622.0
RAD51	-9607.0
UBE2C	-9598.0
CCNE2	-9594.0
CDK4	-9528.0
ZNF439	-9487.0
ZNF470	-9484.0
CDC16	-9479.0
YWHAE	-9457.0
TEAD2	-9436.0
CCNH	-9414.0
POLR2K	-9413.0
NR4A2	-9408.0
SNAPC5	-9393.0
H4C8	-9377.0
PSMC4	-9362.0
COX8A	-9358.0
SPP1	-9354.0
RFC4	-9330.0
MED7	-9269.0
TP53INP1	-9266.0
ZNF619	-9227.0
ZNF680	-9175.0
RRM2B	-9164.0
SKP1	-9156.0
PRELID1	-9144.0
HDAC9	-9141.0
IL2	-9114.0
ZNF274	-9109.0
PPARG	-9074.0
H3-3A	-9072.0
SMARCE1	-9067.0
H2BC21	-9064.0
CDK9	-9061.0
CCNA1	-9044.0
E2F5	-9023.0
SMARCD1	-8997.0
ABCA6	-8990.0
BMP2	-8987.0
TAF10	-8984.0
MAF	-8942.0
CASP10	-8927.0
ZNF233	-8924.0
DDIT4	-8895.0
H2BC5	-8892.0
SCO2	-8890.0
TRIM63	-8879.0
COX18	-8878.0
ZNF770	-8874.0
PRMT1	-8837.0
IL6	-8816.0
ZNF432	-8806.0
PSMA8	-8792.0
ICE2	-8770.0
ZNF804B	-8768.0
YAP1	-8707.0
MED1	-8676.0
ZNF420	-8675.0
INTS14	-8656.0
ZNF485	-8644.0
FAS	-8637.0
ZNF112	-8633.0
HEY1	-8626.0
RAD1	-8622.0
LMO2	-8617.0
TGIF1	-8601.0
MEAF6	-8600.0
MED6	-8572.0
RRAGC	-8538.0
ZNF304	-8518.0
BCL2L14	-8500.0
GATAD2B	-8499.0
CRADD	-8491.0
OCLN	-8485.0
ZNF621	-8479.0
RBM8A	-8468.0
SP7	-8465.0
H4C3	-8439.0
MTA2	-8428.0
ZNF679	-8371.0
ZNF214	-8365.0
SMARCD2	-8345.0
ZNF433	-8293.0
CNOT8	-8284.0
RABGGTB	-8281.0
SLBP	-8275.0
CBX5	-8259.0
SYT10	-8216.0
KAT2B	-8201.0
SOX2	-8177.0
TACO1	-8176.0
NR1H4	-8146.0
PRKAG1	-8140.0
ZNF688	-8128.0
RNU11	-8070.0
PHC1	-8059.0
CHEK1	-8020.0
ZNF549	-8008.0
COX20	-8004.0
YBX1	-8000.0
H3C10	-7994.0
SERPINB13	-7980.0
UBC	-7974.0
TAL1	-7932.0
ANAPC10	-7909.0
TRIM28	-7887.0
H2BC11	-7869.0
ZNF529	-7868.0
HAND2	-7860.0
ZNF431	-7846.0
PSMD12	-7843.0
RBBP8	-7841.0
FOXO1	-7760.0
PRDX2	-7751.0
MAPK1	-7718.0
CR1	-7714.0
PLAGL1	-7695.0
GTF2F1	-7689.0
ZNF418	-7624.0
SATB2	-7606.0
POU4F2	-7595.0
SNAPC3	-7587.0
TAF15	-7585.0
ZNF577	-7580.0
ZNF492	-7573.0
ZNF706	-7571.0
H2BC14	-7552.0
RTF1	-7548.0
COX5A	-7517.0
GATA4	-7503.0
PSMB10	-7431.0
IL2RA	-7427.0
PSMC5	-7419.0
PRDM1	-7407.0
POLR2L	-7397.0
WRN	-7368.0
POLR2D	-7349.0
RRAGA	-7337.0
ELOC	-7318.0
FURIN	-7294.0
HNF4G	-7283.0
ANAPC16	-7276.0
H2BC17	-7263.0
PABPN1	-7259.0
RNU12	-7251.0
E2F7	-7241.0
ZNF25	-7198.0
IFNG	-7165.0
ZNF180	-7151.0
PHAX	-7141.0
ZNF382	-7123.0
PSMB4	-7098.0
BAX	-7080.0
RSPO3	-7077.0
H2BC4	-7072.0
ZNF285	-7061.0
MSX2	-7029.0
BLM	-7010.0
ZNF528	-7000.0
SESN2	-6986.0
ZNF585A	-6979.0
YES1	-6977.0
ZNF566	-6976.0
BTG1	-6953.0
ZFP69B	-6943.0
SUPT16H	-6940.0
ZNF697	-6938.0
H3-3B	-6937.0
YWHAH	-6931.0
TAF9	-6894.0
TXNIP	-6880.0
ZNF839	-6840.0
ZNF641	-6822.0
RAD50	-6818.0
KLF4	-6815.0
ZNF17	-6800.0
H3C2	-6790.0
NPM1	-6785.0
HES1	-6760.0
PSME4	-6754.0
ZNF446	-6748.0
BRIP1	-6712.0
SLC38A9	-6703.0
H2AJ	-6672.0
TNFRSF10A	-6662.0
IHH	-6653.0
ZNF564	-6633.0
INTS7	-6621.0
AGO3	-6613.0
H2BC13	-6590.0
PCGF5	-6552.0
HDAC2	-6547.0
CCN2	-6543.0
YWHAZ	-6541.0
NR2F1	-6540.0
ZNF169	-6534.0
ZNF215	-6527.0
POLR2I	-6513.0
LMO1	-6508.0
TFAP2A	-6495.0
TP53RK	-6478.0
JAG1	-6475.0
NDUFA4	-6467.0
PCF11	-6466.0
H2AC8	-6445.0
NABP1	-6435.0
COX11	-6434.0
ZNF14	-6426.0
PCK1	-6412.0
PF4	-6385.0
ZNF583	-6340.0
ING2	-6336.0
NR2C2AP	-6334.0
CCNG2	-6333.0
SNW1	-6319.0
ZNF704	-6300.0
ZNF222	-6257.0
MAPK14	-6253.0
H2AC7	-6250.5
H2BC7	-6250.5
ITGA5	-6235.0
ZFP2	-6174.0
DDX39A	-6172.0
CCND1	-6159.0
SCO1	-6146.0
AURKA	-6140.0
DLX5	-6136.0
MLLT3	-6133.0
H2AC6	-6100.0
PSMC2	-6092.0
PSME2	-6084.0
ZNF43	-6082.0
SMAD4	-6076.0
RARG	-6058.0
VDR	-6043.0
SRSF7	-6003.0
CDK2	-6001.0
UBE2E1	-5994.0
H2BC8	-5989.0
PSMA3	-5986.0
PRKAA1	-5969.0
GATA3	-5922.0
ZNF792	-5920.0
TPX2	-5907.0
NABP2	-5903.0
CDK13	-5894.0
ZNF701	-5893.0
ZNF764	-5892.0
NR2E1	-5889.0
DDB2	-5888.0
GTF2A2	-5868.0
PSMB8	-5844.0
MAML1	-5839.0
SIRT3	-5825.0
TAF6	-5820.0
SYMPK	-5817.0
FYTTD1	-5794.0
ZNF354C	-5785.0
CCNA2	-5784.0
TGFA	-5777.0
CCND3	-5768.0
GTF2H5	-5748.0
OPRK1	-5744.0
LIFR	-5731.0
SIN3A	-5724.0
H2AC18	-5704.5
H2AC19	-5704.5
GAD1	-5701.0
ZNF665	-5633.0
MEF2C	-5570.0
ZNF597	-5567.0
ZNF334	-5561.0
H3C4	-5557.0
MED4	-5496.0
ZNF709	-5493.0
RNPS1	-5489.0
H2AC14	-5481.0
TNRC6B	-5477.0
RBFOX1	-5461.0
HSPD1	-5428.0
MET	-5427.0
EXO1	-5402.0
COX6B1	-5397.0
ZNF660	-5305.0
BARD1	-5276.0
AIFM2	-5261.0
CCND2	-5248.0
MMP13	-5242.0
ZNF669	-5237.0
ZNF33B	-5235.0
ZNF468	-5220.0
RAD17	-5200.0
TAF13	-5185.0
RBM14	-5176.0
SMAD1	-5175.0
FKBP5	-5170.0
ZNF613	-5156.0
NCBP2	-5148.0
MOBP	-5118.0
ZNF746	-5109.0
ZNF135	-5101.0
H3C12	-5090.0
ZNF442	-5068.0
MLH1	-5056.0
MED10	-5044.0
ESRRG	-5026.0
ZNF703	-4962.0
YWHAQ	-4922.0
RHEB	-4907.0
ZNF875	-4854.0
ZNF234	-4822.0
ZNF419	-4811.0
ELOB	-4810.0
GAD2	-4777.0
PCGF6	-4756.0
NFATC2	-4753.0
AFF4	-4751.0
ZNF101	-4729.0
ZNF480	-4723.0
IWS1	-4704.0
ZNF223	-4698.0
ZNF565	-4690.0
BCL2L11	-4681.0
ZNF552	-4678.0
BCL6	-4663.0
G6PC1	-4655.0
RARB	-4644.0
SMAD3	-4614.0
SUPT4H1	-4613.0
GPX2	-4604.0
PPARGC1A	-4586.0
CDKN2A	-4556.0
TWIST1	-4549.0
IGFBP3	-4543.0
ZNF235	-4535.0
COX5B	-4533.0
ELOA2	-4505.0
CDK6	-4485.0
NR4A3	-4472.0
ZNF74	-4469.0
RHNO1	-4461.0
MDM4	-4448.0
E2F6	-4439.0
PSMA5	-4438.0
CUL1	-4436.0
ZNF18	-4427.0
SRSF1	-4423.0
SRSF2	-4420.0
POMC	-4416.0
RARA	-4410.0
ZNF208	-4402.0
ZNF256	-4391.0
UBA52	-4361.0
BBC3	-4339.0
U2AF1L4	-4338.0
POU2F1	-4327.0
PSMD11	-4325.0
CTSV	-4312.0
ZNF141	-4297.0
PSMD5	-4244.0
PPP2CB	-4240.0
RBBP4	-4237.0
H2BC6	-4207.0
DPY30	-4190.0
ZNF791	-4187.0
TAF1L	-4157.0
YEATS4	-4139.0
ZNF143	-4124.0
H4C6	-4120.0
CDC26	-4109.0
CASP1	-4103.0
CASC3	-4102.0
BDNF	-4052.0
GRIN2A	-4049.0
SPI1	-4047.0
RETN	-4043.0
PERP	-4024.0
USP2	-4022.0
RPRD2	-4016.0
LEO1	-4005.0
ZNF473	-4001.0
MED24	-3995.0
PSMD9	-3987.0
ZNF430	-3983.0
ZNF726	-3980.0
ZNF749	-3977.0
ZNF211	-3933.0
CDC25C	-3918.0
POLR2C	-3916.0
PAX5	-3900.0
RUNX1	-3889.0
SMARCA2	-3877.0
RBPJ	-3875.0
ZNF595	-3859.0
PTEN	-3849.0
MYC	-3827.0
H3C11	-3817.0
CRH	-3773.0
POU4F1	-3751.0
ZNF747	-3744.0
KMT2A	-3737.0
MED8	-3735.0
UBE2S	-3726.0
ZNF610	-3718.0
ZKSCAN8	-3708.0
ZNF607	-3700.0
CDK7	-3687.0
SKP2	-3685.0
ARID2	-3677.0
ZNF300	-3661.0
ZNF554	-3615.0
ZNF546	-3613.0
KCTD1	-3596.0
GTF2H1	-3579.0
SESN3	-3577.0
TAF5	-3574.0
SIN3B	-3563.0
SGK1	-3558.0
ZNF33A	-3539.0
CSTF1	-3526.0
BRD2	-3524.0
ZNF454	-3509.0
AURKB	-3499.0
JUNB	-3457.0
TNFRSF10B	-3451.0
CDC23	-3430.0
PSMA6	-3425.0
ZNF99	-3405.0
ZNF426	-3399.0
GTF2A1	-3386.0
ATRIP	-3365.0
INTS4	-3312.0
SOCS3	-3309.0
KDM5B	-3303.0
RPAP2	-3298.0
THOC6	-3296.0
PTPN1	-3259.0
ESR2	-3242.0
ZNF226	-3241.0
GEM	-3238.0
NFKB1	-3211.0
CCNG1	-3210.0
SKIL	-3197.0
ZNF26	-3183.0
RNF2	-3178.0
RBX1	-3122.0
H4C13	-3097.0
PSMC1	-3076.0
CPSF3	-3075.0
RBBP5	-3068.0
HDAC11	-3067.0
TFAP2B	-3046.0
ITGBL1	-3041.0
ZNF605	-3038.0
PSME3	-3024.0
ZNF684	-3010.0
MAPKAPK5	-3000.0
GSK3B	-2980.0
RNF111	-2974.0
PSMB9	-2972.0
ZNF555	-2954.0
GPAM	-2944.0
MAML2	-2936.0
NR6A1	-2925.0
CDK12	-2919.0
CNOT2	-2903.0
SNRPF	-2877.0
TP53I3	-2868.0
UBE2D3	-2867.0
ZNF557	-2854.0
PAF1	-2848.0
ZNF436	-2843.0
ZNF136	-2835.0
ZNF155	-2833.0
YY1	-2808.0
ZNF571	-2781.0
SLC2A3	-2778.0
LRPPRC	-2720.0
ZNF347	-2719.0
ARNT	-2718.0
AUTS2	-2704.0
PPP1R13L	-2657.0
EGFR	-2625.0
ZNF570	-2617.0
ZNF586	-2616.0
CREB1	-2614.0
REST	-2601.0
HDAC10	-2600.0
RYBP	-2596.0
SP1	-2592.0
ZNF354B	-2544.0
ZNF530	-2532.0
EAF2	-2522.0
PRDX1	-2515.0
PRKCQ	-2494.0
MED26	-2475.0
ZNF415	-2455.0
PPP2CA	-2430.0
PPARGC1B	-2417.0
ZNF267	-2401.0
ZNF486	-2391.0
GLS	-2388.0
PITX2	-2369.0
RAD9B	-2357.0
NUAK1	-2326.0
SRSF6	-2316.0
ZNF266	-2304.0
TXN	-2287.0
CNOT6L	-2281.0
ZNF682	-2273.0
H2AZ2	-2221.0
THRB	-2203.0
ANAPC1	-2192.0
CCNT2	-2188.0
ZNF212	-2186.0
CNOT10	-2175.0
PRDM7	-2136.0
INTS9	-2128.0
PSMD1	-2120.0
CHTOP	-2110.0
SRRM1	-2062.0
CPSF2	-2027.0
ZNF616	-2016.0
ZNF461	-2010.0
KAT5	-1954.0
ZNF385A	-1939.0
INTS13	-1929.0
ZNF331	-1896.0
ZNF710	-1893.0
LAMTOR5	-1886.0
ZNF445	-1877.0
NPY	-1832.0
ELL3	-1791.0
PSMB5	-1772.0
NKX2-5	-1760.0
SRSF4	-1744.0
COX19	-1736.0
RUNX2	-1732.0
ZNF550	-1697.0
DDIT3	-1681.0
YWHAG	-1652.0
ZNF460	-1632.0
MIR132	-1621.0
CNOT11	-1620.0
TP53BP2	-1615.0
DLX6	-1581.0
ASH2L	-1576.0
RBL2	-1575.0
SRSF3	-1573.0
PRDX5	-1554.0
SOX9	-1552.0
PSMA1	-1545.0
RPS27A	-1544.0
CSNK2B	-1533.0
H2AZ1	-1527.0
CAMK4	-1525.0
TAF4B	-1508.0
PIN1	-1506.0
ZNF114	-1498.0
CAV1	-1489.0
ZNF771	-1479.0
NR2F6	-1473.0
CDC40	-1463.0
GTF2E1	-1461.0
PRKAG3	-1446.0
MAML3	-1443.0
GTF2H3	-1441.0
MDM2	-1436.0
MED31	-1394.0
KRAS	-1382.0
PSMB3	-1361.0
MNAT1	-1328.0
RMI1	-1295.0
BLK	-1260.0
BMI1	-1236.0
ZNF568	-1206.0
H4C2	-1183.0
TP53	-1167.0
NBN	-1104.0
KRBOX5	-1102.0
ZNF184	-1099.0
SRF	-1093.0
KAT6A	-1082.0
ZNF37A	-1069.0
GRIN2B	-1066.0
CBFB	-1044.0
PRMT6	-1036.0
RORA	-1030.0
GAMT	-1018.0
NRBP1	-954.0
CDC7	-952.0
FANCC	-944.0
RNU4ATAC	-907.0
SNRPE	-904.0
ELOA	-878.0
ACTL6A	-828.0
ZNF543	-788.0
NAMPT	-773.0
THRA	-767.0
ZNF506	-759.0
BNIP3L	-752.0
PHC3	-751.0
H4C1	-737.0
ZNF599	-713.0
CBX4	-694.0
ZNF670	-693.0
CSNK2A1	-662.0
PSME1	-658.0
ZNF548	-638.0
POLDIP3	-636.0
PCNA	-634.0
CCNE1	-622.0
H4C5	-618.0
ZNF71	-581.0
GTF2F2	-573.0
SETD9	-566.0
CNOT7	-558.0
AGO4	-531.0
RFC2	-527.0
TAF11	-484.0
TCF7L1	-454.0
ZNF692	-449.0
RXRB	-440.0
TAF12	-438.0
CPSF6	-390.0
NCBP1	-381.0
H2BC15	-371.0
MYB	-365.0
YWHAB	-355.0
NR3C1	-354.0
VENTX	-343.0
APAF1	-322.0
STAT1	-317.0
SRRT	-312.0
MRE11	-301.0
ZNF200	-263.0
TSC1	-239.0
ZNF20	-223.0
PRMT5	-221.0
PAPOLA	-216.0
ZNF551	-207.0
ZNF45	-179.0
SRSF11	-169.0
SNRPD3	-159.0
ZNF776	-140.0
TBL1XR1	-134.0
ZNF28	-127.0
PPM1A	-126.0
FBXW7	-88.0
ABL1	-86.0
ZNF230	-80.0
H2BC1	-54.0
ATF2	-41.0
RAD9A	-14.0
COX16	-12.0
PLK2	-9.0
SEM1	-1.0
SSRP1	7.0
PRR5	29.0
ELF2	38.0
CTLA4	45.0
FBXO32	71.0
CAMK2D	77.0
ZFP37	85.0
POLR2B	117.0
CNOT9	125.0
CNOT6	187.0
NFYB	191.0
RFFL	226.0
PIP4K2C	243.0
ZNF708	273.0
NR1D2	312.0
PSMD8	315.0
ZNF540	335.0
ZKSCAN4	341.0
ZNF425	352.0
MOV10	387.0
ZNF227	395.0
ZNF30	396.0
ZNF224	404.0
EPC1	405.0
JUN	408.0
ZNF544	418.0
RXRG	424.0
CSNK2A2	438.0
LDB1	472.0
FIP1L1	484.0
ZNF567	494.0
ARID1A	515.0
ZNF248	523.0
INTS2	538.0
ZNF496	566.0
CYCS	595.0
CBX2	599.0
CDKN1A	606.0
TFAP2C	621.0
NELFE	643.0
TAF2	646.0
NR1D1	661.0
THOC7	664.0
CSF1R	671.0
H2BC12	672.0
TCEA1	677.0
CASP6	696.0
NUDT21	703.0
TEAD1	707.0
ZNF10	709.0
TRIAP1	765.0
EP300	781.0
ZNF785	788.0
ZKSCAN1	793.0
E2F4	795.0
ZNF615	812.0
ZNF160	821.0
NRBF2	841.0
ZIM3	846.0
ICE1	850.0
TOPBP1	872.0
ARID1B	905.0
ZNF718	910.0
ZNF398	927.0
POLR2G	936.0
PSMA7	942.0
ZNF354A	947.0
ZNF655	966.0
ITGA4	980.0
ZNF668	984.0
ZNF778	999.0
ZNF799	1018.0
ANAPC7	1021.0
CCNB1	1056.0
PSMA2	1059.0
GLI3	1067.0
ZNF649	1076.0
ZNF23	1082.0
ZFHX3	1095.0
MAP2K6	1098.0
TJP1	1115.0
ZNF34	1122.0
TCF7L2	1128.0
SIRT1	1151.0
CCNT1	1152.0
PSMD7	1158.0
PVALB	1171.0
WWP1	1217.0
NR1H2	1220.0
PPP2R1A	1222.0
FOXG1	1252.0
COX6A1	1265.0
ZNF416	1322.0
ZNF287	1335.0
PPARD	1344.0
CBX8	1366.0
GPRIN1	1374.0
ZNF471	1379.0
BRCA1	1391.0
INTS6	1413.0
ZIM2	1418.0
PINK1	1427.0
KCTD15	1432.0
PLXNA4	1456.0
LBR	1457.0
CNOT4	1474.0
WWOX	1499.0
TBX5	1523.0
PSMB2	1566.0
PPP2R5C	1594.0
INTS3	1603.0
MED23	1632.0
MDC1	1639.0
ZNF77	1647.0
ZNF195	1654.0
ZNF317	1668.0
CPSF7	1694.0
EAF1	1704.0
CDK5	1717.0
CBX3	1720.0
XPO1	1743.0
ZNF311	1745.0
ZNF606	1749.0
COX4I1	1790.0
ZNF624	1818.0
KMT2C	1821.0
TFAP2D	1824.0
ZNF250	1837.0
ZC3H11A	1841.0
ARID3A	1849.0
HDAC3	1872.0
ALYREF	1883.0
NCOR1	1885.0
RMI2	1921.0
ZNF761	1925.0
RNMT	1929.0
L3MBTL2	1939.0
PRKCB	1947.0
THOC1	1952.0
RNGTT	1953.0
NOP2	1958.0
LSM11	1965.0
NR3C2	2006.0
CSTF2T	2008.0
USP7	2014.0
INTS12	2039.0
CDKN1B	2040.0
EED	2064.0
ZNF154	2069.0
POLR2E	2087.0
ZNF79	2099.0
ZNF786	2100.0
TP63	2101.0
ELL2	2102.0
ZNF627	2130.0
RET	2149.0
COL1A2	2152.0
SNAPC1	2153.0
ERBB2	2158.0
HIPK1	2167.0
INTS8	2170.0
ZFP1	2172.0
COX6C	2174.0
NR5A2	2192.0
GLS2	2197.0
KMT2E	2202.0
DHX38	2217.0
CAMK2G	2220.0
SLU7	2221.0
TNFRSF18	2234.0
RFC5	2266.0
SMAD7	2299.0
LEF1	2307.0
UBE2I	2333.0
DLL1	2367.0
PSMD14	2369.0
HIVEP3	2384.0
ZNF70	2395.0
ATXN3	2433.0
SRSF5	2434.0
BTG2	2439.0
FANCD2	2444.0
TAF3	2448.0
CCNK	2510.0
CDKN2B	2511.0
ZKSCAN3	2514.0
NR5A1	2527.0
TAF7	2596.0
NR2C2	2606.0
CNOT3	2638.0
ZNF443	2662.0
TXNRD1	2669.0
BMAL1	2675.0
ZNF383	2677.0
GTF2H4	2687.0
E2F8	2697.0
ZNF490	2709.0
ZNF225	2718.0
RRAGD	2720.0
SST	2745.0
ZFP28	2758.0
ZNF510	2773.0
PSMC3	2777.0
POLR2H	2784.0
PIP4P1	2793.0
TEAD3	2827.0
ZNF221	2904.0
ZNF582	2932.0
ITGA2B	2935.0
H2AC4	2947.0
ESRRA	2961.0
MAPK11	2972.0
SESN1	2984.0
SOCS4	3010.0
LAMTOR4	3035.0
SNRPG	3043.0
OPRM1	3059.0
PRKAB2	3067.0
RAD51D	3072.0
LSM10	3090.0
FOXO3	3101.0
PHC2	3102.0
EZH2	3126.0
TBP	3128.0
COL1A1	3142.0
CITED2	3145.0
TRPC3	3155.0
RPA3	3162.0
MED17	3180.0
ITGAL	3181.0
PHF20	3189.0
TFAP2E	3193.0
RBFOX3	3208.0
ATM	3236.0
RFC3	3245.0
H4C16	3253.0
ZNF343	3256.0
WWTR1	3261.0
ZNF138	3287.0
ANAPC11	3289.0
PSMD13	3304.0
ZNF324B	3306.0
PGR	3346.0
SMYD2	3347.0
GTF2E2	3352.0
ZFP30	3390.0
HIPK2	3401.0
BRD7	3417.0
PCGF2	3422.0
E2F1	3427.0
RING1	3445.0
INTS11	3448.0
CDK1	3449.0
ZNF333	3479.0
ZNF205	3492.0
CTNNB1	3514.0
ANAPC5	3520.0
SURF1	3528.0
HDAC7	3545.0
CTSK	3556.0
PSMB7	3558.0
ACTL6B	3566.0
FANCI	3586.0
ZNF584	3613.0
THOC5	3615.0
PSMD4	3642.0
YAF2	3673.0
PSMD2	3699.0
INTS10	3701.0
TNRC6A	3724.0
PPM1D	3741.0
SARNP	3756.0
ZKSCAN5	3762.0
IGFBP1	3764.0
TGFB1	3769.0
CALM1	3777.0
MYBL2	3780.0
ZNF560	3785.0
ZNF563	3804.0
RXRA	3824.0
AKT3	3841.0
INTS5	3882.0
SRSF9	3890.0
TOP3A	3894.0
MED13	3912.0
ZNF667	3936.0
ITCH	3965.0
CDK8	3969.0
NR2C1	3995.0
PMAIP1	4001.0
ZNF671	4017.0
MAPKAP1	4030.0
ZNF350	4060.0
PSMA4	4073.0
PMS2	4074.0
HDAC5	4084.0
CSF2	4089.0
GSR	4098.0
L3MBTL1	4111.0
TNKS1BP1	4112.0
NFYC	4149.0
TGIF2	4169.0
ZIK1	4180.0
DAXX	4187.0
BRPF3	4241.0
MEN1	4253.0
H3C1	4262.0
ZNF714	4265.0
MSH2	4292.0
SMAD2	4309.0
PRKACA	4352.0
CHEK2	4361.0
NEDD4L	4363.0
ZNF573	4398.0
PSMC6	4442.0
ZNF793	4452.0
SMARCD3	4464.0
FZR1	4472.0
PSMD6	4479.0
TP73	4484.0
MED15	4488.0
SMARCC1	4497.0
MBD3	4522.0
CENPJ	4530.0
ZNF782	4579.0
ZFP69	4583.0
ELL	4599.0
ZNF263	4605.0
ZNF189	4606.0
THBS1	4615.0
ESR1	4621.0
ZNF2	4625.0
H2BC26	4643.0
CNOT1	4659.0
UBE2D1	4660.0
GATAD2A	4692.0
CAMK2A	4700.0
NELFCD	4723.0
MLST8	4747.0
ZNF773	4748.0
PBRM1	4775.0
IQSEC3	4783.0
SNAPC2	4799.0
ZNF140	4802.0
TRIM33	4812.0
AXIN1	4866.0
SUPT6H	4901.0
MYL9	4904.0
NCOR2	4914.0
FOS	4918.0
ZNF736	4945.0
CAT	4947.0
MAGOHB	4952.0
CASP2	4962.0
ANAPC15	5002.0
ZSCAN32	5003.0
LAMTOR2	5007.0
ZNF569	5023.0
DEK	5037.0
RORC	5052.0
ZNF547	5068.0
ANAPC4	5089.0
ZSCAN25	5100.0
TAF8	5102.0
RPA1	5108.0
ZNF664	5143.0
ERCC3	5144.0
NR1I3	5145.0
ZNF730	5152.0
ZNF562	5167.0
SMURF1	5187.0
PSMB6	5196.0
PSMF1	5201.0
GPI	5203.0
ZNF484	5205.0
NR1I2	5208.0
COX7A2L	5212.0
H4C9	5218.0
CHD4	5228.0
SSU72	5241.0
NOC2L	5258.0
GTF2B	5276.0
ZNF716	5278.0
H2BC9	5307.5
H3C7	5307.5
ZFP90	5316.0
PIP4K2A	5324.0
ZNF324	5388.0
PSMB1	5414.0
NOTCH4	5439.0
ZNF441	5446.0
KCTD6	5452.0
SMURF2	5454.0
HNF4A	5465.0
HUS1	5471.0
TCF7	5475.0
ZNF254	5478.0
BRPF1	5496.0
JMY	5500.0
MIR137	5514.0
PRKAG2	5528.0
ZNF519	5586.0
POU2F2	5592.0
ZNF517	5597.0
ZNF740	5603.0
ZNF691	5618.0
SUPT5H	5619.0
PPP1R13B	5672.0
GRIA2	5679.0
NELFA	5698.0
EIF4A3	5714.0
HTT	5715.0
SKI	5720.0
ATR	5740.0
CDC73	5753.0
ZNF124	5762.0
ZNF273	5778.0
NR4A1	5829.0
MSTN	5851.0
ZNF417	5880.0
VEGFA	5881.0
MGA	5884.0
WDR33	5892.0
ESRRB	5894.0
ZNF3	5907.0
NFYA	5913.0
DDX39B	5923.0
TCF12	5998.0
MIR24-1	6007.0
CDC27	6028.0
ZNF689	6039.0
ATAD2	6048.0
CEBPB	6090.0
ZNF596	6130.0
ZNF681	6142.0
CDK5R1	6149.0
CGA	6173.0
DYRK2	6180.0
CCNC	6191.0
MAPK3	6201.0
TMEM219	6212.0
NOTCH3	6234.0
KCNIP3	6244.0
SMAD6	6271.0
ZNF394	6298.0
ZNF202	6347.0
RNF34	6348.0
CSTF3	6357.0
RGCC	6370.0
ZNF774	6389.0
HEY2	6398.0
PLK3	6403.0
RB1	6425.0
ZNF777	6453.0
PRKAB1	6504.0
CLDN5	6511.0
BIRC5	6513.0
H4C4	6524.0
KMT2B	6530.0
ZKSCAN7	6533.0
PPARA	6536.0
CBX6	6575.0
ZNF675	6587.0
H3C6	6602.0
ZNF700	6609.0
LAMTOR1	6612.0
ZNF257	6633.0
POLR2F	6656.0
LAMTOR3	6679.0
PML	6714.0
ZNF724	6715.0
ZNF514	6744.0
SNRPB	6751.0
NDRG1	6765.0
DNA2	6788.0
SETD1B	6789.0
RICTOR	6796.0
TIGAR	6802.0
NOTCH1	6821.0
CPSF4	6824.0
BANP	6862.0
RPRD1A	6874.0
ZNF264	6904.0
TNFRSF10D	6929.0
ZNF558	6930.0
ZNF253	6976.0
ZNF772	7001.0
ZNF662	7004.0
CTR9	7060.0
MAX	7070.0
ERCC2	7083.0
RRM2	7094.0
ZNF721	7122.0
SCMH1	7139.0
ZNF559	7168.0
ZNF696	7171.0
CPSF1	7172.0
ZNF337	7173.0
TFDP2	7179.0
STK11	7226.0
CHD3	7250.0
ZNF860	7285.0
ZNF713	7349.0
H4C12	7358.0
ZNF600	7359.0
TNRC6C	7431.0
ZNF727	7450.0
MED25	7478.0
ZNF735	7511.0
COX7C	7538.0
HDAC1	7551.0
RUNX3	7557.0
MED16	7560.0
ZNF133	7571.0
ZNF268	7583.0
PTPN4	7596.0
RELA	7644.0
EHMT1	7646.0
ZNF286A	7653.0
ZNF75A	7656.0
ZC3H8	7690.0
ZNF302	7724.0
POLR2A	7751.0
PRELID3A	7758.0
MLLT1	7760.0
NPAS4	7801.0
AKT1	7830.0
KRBA1	7848.0
STEAP3	7868.0
RABGGTA	7870.0
PCBP4	7883.0
ARNT2	7910.0
RPRD1B	7937.0
ANAPC2	7945.0
ZNF213	7954.0
U2AF2	7974.0
ZNF282	7989.0
ZNF197	8024.0
PARP1	8062.0
LGALS3	8085.0
ZNF775	8096.0
KAT2A	8115.0
PSMD3	8120.0
UCMA	8149.0
GCK	8197.0
TEAD4	8219.0
CTDP1	8234.0
APOE	8250.0
H2BC3	8253.0
ZNF611	8266.0
CAMK2B	8374.0
SMARCC2	8442.0
ZNF12	8464.0
ZNF707	8480.0
MED27	8481.0
GLI2	8503.0
PDPK1	8583.0
EHMT2	8607.0
NELFB	8624.0
CITED4	8633.0
PIP4K2B	8634.0
ZNF585B	8683.0
MTOR	8691.0
ZFP14	8723.0
SRC	8731.0
WDR5	8748.0
MED30	8812.0
AGO2	8830.0
ZFPM1	8845.0
DGCR8	8864.0
ZNF500	8871.0
STUB1	8876.0
ZNF589	8878.0
SERPINE1	8901.0
PPP2R1B	8914.0
ZNF493	8949.0
ZNF92	8961.0
SFN	8990.0
CREBBP	9058.0
ZNF19	9062.0
H3C3	9119.0
SREBF1	9158.0
INTS1	9172.0
TWIST2	9207.0
BRD1	9228.0
AGO1	9230.0
H2BC10	9234.0
RPTOR	9243.0
SETD1A	9250.0
SMARCA4	9287.0
SUZ12	9312.0
CGB8	9324.0
ZNF483	9351.0
TFDP1	9373.0
BID	9442.0
TSC2	9448.0
ZNF738	9503.0
NPPA	9533.0
ZNF626	9542.0
H4C11	9599.0
HDAC4	9605.0
SKIC8	9622.0
SMARCB1	9632.0
AKT2	9642.0
NR2E3	9669.0
ING5	9695.0
ZNF678	9709.0
POLR2J	9748.0
TAF4	9763.0
PSMB11	9803.0
CARM1	9874.0
H3C8	9880.0
ZNF587	9926.0
TP53AIP1	9937.0
KMT2D	9986.0
NR0B2	10011.0
ZNF556	10022.0
ZNF750	10025.0
ZNF737	10063.0
ZNF100	10186.0
ZNF699	10203.0
NOTCH2	10299.0
INS	10301.0
SNAPC4	10369.0
TCF3	10398.0
PIDD1	10445.0
FOXO6	10462.0
AGRP	10518.0
ZNF717	10625.0
CGB5	10952.0

---

REACTOME_CONSTITUTIVE_SIGNALING_BY_ABERRANT_PI3K_IN_CANCER

REACTOME_CONSTITUTIVE_SIGNALING_BY_ABERRANT_PI3K_IN_CANCER

	478
set	REACTOME_CONSTITUTIVE_SIGNALING_BY_ABERRANT_PI3K_IN_CANCER
setSize	77
pANOVA	0.00451
s.dist	-0.187
p.adjustANOVA	0.176

Top enriched genes

Top 20 genes

GeneID	Gene Rank
AREG	-10988
HGF	-10497
HBEGF	-10493
CD86	-10367
FGF20	-9972
KIT	-9851
PTPN11	-9664
PDGFB	-9654
NRG3	-9653
PIK3R2	-9426
EREG	-9027
RHOG	-8996
FGF8	-8641
RAC1	-8610
TRAT1	-8549
PDGFRA	-8199
FGF19	-7788
PIK3AP1	-7787
FGF3	-7376
EPGN	-7315

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
AREG	-10988
HGF	-10497
HBEGF	-10493
CD86	-10367
FGF20	-9972
KIT	-9851
PTPN11	-9664
PDGFB	-9654
NRG3	-9653
PIK3R2	-9426
EREG	-9027
RHOG	-8996
FGF8	-8641
RAC1	-8610
TRAT1	-8549
PDGFRA	-8199
FGF19	-7788
PIK3AP1	-7787
FGF3	-7376
EPGN	-7315
FGF9	-7195
ERBB4	-6856
KL	-6471
FGF23	-6468
GAB1	-6416
FGF10	-6358
GAB2	-6223
TGFA	-5777
PIK3R1	-5752
ICOS	-5737
NRG1	-5528
MET	-5427
EGF	-5404
FYN	-5019
KITLG	-4853
NRG4	-4442
FGF17	-4415
FGF5	-4107
BTC	-4048
LCK	-3915
FLT3	-3438
ESR2	-3242
PIK3R3	-3209
GRB2	-2984
EGFR	-2625
FGF1	-2378
FGF7	-1520
FGF4	-1054
PIK3CA	-717
VAV1	-400
RAC2	892
IRS1	893
PIK3CD	2150
ERBB2	2158
FGFR1	2177
PDGFA	2732
STRN	3025
ESR1	4621
ERBB3	4703
IRS2	4801
FGFR2	4834
FLT3LG	4867
FGF2	5483
NRG2	5631
FRS2	6075
CD80	6145
PIK3CB	6910
KLB	7467
CD19	7530
FGF22	7577
PDGFRB	8213
FGF18	8225
SRC	8731
FGF6	8910
FGFR3	9212
CD28	9523
FGFR4	9541

---

REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1

REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1

	1272
set	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1
setSize	229
pANOVA	0.00466
s.dist	-0.109
p.adjustANOVA	0.176

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MIR27A	-10780
NFE2	-10684
GP1BA	-10671
IL3	-10344
GATA2	-10325
H2AC20	-10322
CTSL	-10181
ELF1	-10159
UBB	-9702
PTPN11	-9664
H2AX	-9652
CCNH	-9414
H4C8	-9377
PSMC4	-9362
IL2	-9114
H3-3A	-9072
SMARCE1	-9067
H2BC21	-9064
SMARCD1	-8997
H2BC5	-8892

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MIR27A	-10780.0
NFE2	-10684.0
GP1BA	-10671.0
IL3	-10344.0
GATA2	-10325.0
H2AC20	-10322.0
CTSL	-10181.0
ELF1	-10159.0
UBB	-9702.0
PTPN11	-9664.0
H2AX	-9652.0
CCNH	-9414.0
H4C8	-9377.0
PSMC4	-9362.0
IL2	-9114.0
H3-3A	-9072.0
SMARCE1	-9067.0
H2BC21	-9064.0
SMARCD1	-8997.0
H2BC5	-8892.0
PRMT1	-8837.0
PSMA8	-8792.0
YAP1	-8707.0
LMO2	-8617.0
OCLN	-8485.0
H4C3	-8439.0
SMARCD2	-8345.0
KAT2B	-8201.0
PHC1	-8059.0
H3C10	-7994.0
SERPINB13	-7980.0
UBC	-7974.0
TAL1	-7932.0
H2BC11	-7869.0
PSMD12	-7843.0
CR1	-7714.0
H2BC14	-7552.0
PSMB10	-7431.0
IL2RA	-7427.0
PSMC5	-7419.0
H2BC17	-7263.0
IFNG	-7165.0
PSMB4	-7098.0
RSPO3	-7077.0
H2BC4	-7072.0
H3-3B	-6937.0
H3C2	-6790.0
PSME4	-6754.0
H2AJ	-6672.0
AGO3	-6613.0
H2BC13	-6590.0
PCGF5	-6552.0
LMO1	-6508.0
H2AC8	-6445.0
PF4	-6385.0
H2AC7	-6250.5
H2BC7	-6250.5
CCND1	-6159.0
H2AC6	-6100.0
PSMC2	-6092.0
PSME2	-6084.0
H2BC8	-5989.0
PSMA3	-5986.0
GATA3	-5922.0
PSMB8	-5844.0
CCND3	-5768.0
LIFR	-5731.0
SIN3A	-5724.0
H2AC18	-5704.5
H2AC19	-5704.5
H3C4	-5557.0
H2AC14	-5481.0
TNRC6B	-5477.0
CCND2	-5248.0
H3C12	-5090.0
NFATC2	-4753.0
CDK6	-4485.0
NR4A3	-4472.0
PSMA5	-4438.0
UBA52	-4361.0
PSMD11	-4325.0
CTSV	-4312.0
PSMD5	-4244.0
H2BC6	-4207.0
DPY30	-4190.0
H4C6	-4120.0
SPI1	-4047.0
PSMD9	-3987.0
PAX5	-3900.0
RUNX1	-3889.0
SMARCA2	-3877.0
H3C11	-3817.0
KMT2A	-3737.0
CDK7	-3687.0
ARID2	-3677.0
SIN3B	-3563.0
PSMA6	-3425.0
SOCS3	-3309.0
RNF2	-3178.0
H4C13	-3097.0
PSMC1	-3076.0
RBBP5	-3068.0
PSME3	-3024.0
PSMB9	-2972.0
GPAM	-2944.0
AUTS2	-2704.0
RYBP	-2596.0
PRKCQ	-2494.0
H2AZ2	-2221.0
PSMD1	-2120.0
PSMB5	-1772.0
RUNX2	-1732.0
ASH2L	-1576.0
PSMA1	-1545.0
RPS27A	-1544.0
CSNK2B	-1533.0
H2AZ1	-1527.0
PSMB3	-1361.0
MNAT1	-1328.0
BLK	-1260.0
BMI1	-1236.0
H4C2	-1183.0
CBFB	-1044.0
PRMT6	-1036.0
ACTL6A	-828.0
PHC3	-751.0
H4C1	-737.0
CBX4	-694.0
CSNK2A1	-662.0
PSME1	-658.0
H4C5	-618.0
AGO4	-531.0
H2BC15	-371.0
MYB	-365.0
ABL1	-86.0
H2BC1	-54.0
SEM1	-1.0
ELF2	38.0
CTLA4	45.0
PSMD8	315.0
MOV10	387.0
CSNK2A2	438.0
LDB1	472.0
ARID1A	515.0
CBX2	599.0
H2BC12	672.0
EP300	781.0
ARID1B	905.0
PSMA7	942.0
PSMA2	1059.0
TJP1	1115.0
PSMD7	1158.0
CBX8	1366.0
PSMB2	1566.0
KMT2C	1821.0
PRKCB	1947.0
KMT2E	2202.0
TNFRSF18	2234.0
PSMD14	2369.0
PSMC3	2777.0
ITGA2B	2935.0
H2AC4	2947.0
SOCS4	3010.0
PHC2	3102.0
H4C16	3253.0
PSMD13	3304.0
HIPK2	3401.0
RING1	3445.0
CTSK	3556.0
PSMB7	3558.0
ACTL6B	3566.0
PSMD4	3642.0
YAF2	3673.0
PSMD2	3699.0
TNRC6A	3724.0
ITCH	3965.0
PSMA4	4073.0
CSF2	4089.0
H3C1	4262.0
PSMC6	4442.0
SMARCD3	4464.0
PSMD6	4479.0
TP73	4484.0
SMARCC1	4497.0
THBS1	4615.0
ESR1	4621.0
H2BC26	4643.0
PBRM1	4775.0
AXIN1	4866.0
MYL9	4904.0
PSMB6	5196.0
PSMF1	5201.0
H4C9	5218.0
H2BC9	5307.5
H3C7	5307.5
PSMB1	5414.0
KCTD6	5452.0
TCF12	5998.0
CLDN5	6511.0
H4C4	6524.0
KMT2B	6530.0
CBX6	6575.0
H3C6	6602.0
PML	6714.0
SETD1B	6789.0
SCMH1	7139.0
H4C12	7358.0
TNRC6C	7431.0
HDAC1	7551.0
LGALS3	8085.0
PSMD3	8120.0
H2BC3	8253.0
SMARCC2	8442.0
SRC	8731.0
WDR5	8748.0
AGO2	8830.0
ZFPM1	8845.0
CREBBP	9058.0
H3C3	9119.0
AGO1	9230.0
H2BC10	9234.0
SETD1A	9250.0
SMARCA4	9287.0
H4C11	9599.0
SMARCB1	9632.0
PSMB11	9803.0
H3C8	9880.0
KMT2D	9986.0
TCF3	10398.0

---

REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

	536
set	REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS
setSize	55
pANOVA	0.00471
s.dist	0.22
p.adjustANOVA	0.176

Top enriched genes

Top 20 genes

GeneID	Gene Rank
LAMA5	10157
ITGB4	9977
SDC4	9285
COL5A1	9262
ACTN1	9198
LAMC3	8916
LAMB2	8324
COL10A1	8239
VTN	7308
DDR1	7118
COL3A1	6950
COL11A2	6918
DDR2	6735
LAMA3	6649
ITGAV	6399
HSPG2	6016
FGF2	5483
LAMC2	5138
DAG1	5020
SDC1	4882

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
LAMA5	10157
ITGB4	9977
SDC4	9285
COL5A1	9262
ACTN1	9198
LAMC3	8916
LAMB2	8324
COL10A1	8239
VTN	7308
DDR1	7118
COL3A1	6950
COL11A2	6918
DDR2	6735
LAMA3	6649
ITGAV	6399
HSPG2	6016
FGF2	5483
LAMC2	5138
DAG1	5020
SDC1	4882
ITGA2	4645
THBS1	4615
COL4A2	4461
TTR	3955
TGFB1	3769
PRKCA	3721
FN1	3290
COL1A1	3142
AGRN	3030
COL5A2	3027
PDGFA	2732
ITGB5	2713
COL11A1	2529
COL4A1	2436
TNC	2339
ITGA6	2165
COL1A2	2152
LAMA1	1758
ITGB3	248
ITGB1	-101
LAMB3	-250
COL2A1	-389
LAMA4	-451
NRXN1	-551
LAMA2	-1404
LAMC1	-3091
LAMB1	-3602
NTN4	-5928
COL5A3	-6711
SDC3	-7400
COL4A3	-7747
SDC2	-8430
COL4A4	-9050
TRAPPC4	-9645
PDGFB	-9654

---

REACTOME_INTERLEUKIN_3_INTERLEUKIN_5_AND_GM_CSF_SIGNALING

REACTOME_INTERLEUKIN_3_INTERLEUKIN_5_AND_GM_CSF_SIGNALING

	839
set	REACTOME_INTERLEUKIN_3_INTERLEUKIN_5_AND_GM_CSF_SIGNALING
setSize	45
pANOVA	0.00498
s.dist	-0.242
p.adjustANOVA	0.178

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IL3	-10344
UBB	-9702
PTPN11	-9664
PIK3R2	-9426
JAK1	-9200
IL2	-9114
STAT5A	-8197
UBC	-7974
SHC1	-7816
TEC	-7793
IL2RA	-7427
SYK	-7342
LYN	-7312
YES1	-6977
YWHAZ	-6541
HCK	-6454
CRKL	-6411
GAB2	-6223
PIK3R1	-5752
FYN	-5019

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IL3	-10344
UBB	-9702
PTPN11	-9664
PIK3R2	-9426
JAK1	-9200
IL2	-9114
STAT5A	-8197
UBC	-7974
SHC1	-7816
TEC	-7793
IL2RA	-7427
SYK	-7342
LYN	-7312
YES1	-6977
YWHAZ	-6541
HCK	-6454
CRKL	-6411
GAB2	-6223
PIK3R1	-5752
FYN	-5019
UBA52	-4361
PTPN6	-3922
IL2RB	-3400
PIK3R3	-3209
RAPGEF1	-3164
GRB2	-2984
INPP5D	-2607
STAT5B	-2385
RPS27A	-1544
PIK3CA	-717
VAV1	-400
JAK3	218
CBL	556
IL5	1605
BLNK	1792
PIK3CD	2150
CRK	2872
SOS1	3385
CSF2	4089
PRKACA	4352
PIK3CB	6910
JAK2	7130
IL5RA	7931
INPPL1	8693
CSF2RB	9948

---

REACTOME_DAP12_SIGNALING

REACTOME_DAP12_SIGNALING

	485
set	REACTOME_DAP12_SIGNALING
setSize	27
pANOVA	0.00518
s.dist	-0.311
p.adjustANOVA	0.178

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TYROBP	-11000
KLRD1	-10968
LCP2	-10311
TREM2	-9736
PIK3R2	-9426
B2M	-9228
NRAS	-9202
KLRK1	-8998
RAC1	-8610
SHC1	-7816
SYK	-7342
HLA-E	-6243
PIK3R1	-5752
FYN	-5019
LCK	-3915
PLCG2	-3090
GRB2	-2984
VAV3	-2932
KRAS	-1382
GRAP2	-1305

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TYROBP	-11000
KLRD1	-10968
LCP2	-10311
TREM2	-9736
PIK3R2	-9426
B2M	-9228
NRAS	-9202
KLRK1	-8998
RAC1	-8610
SHC1	-7816
SYK	-7342
HLA-E	-6243
PIK3R1	-5752
FYN	-5019
LCK	-3915
PLCG2	-3090
GRB2	-2984
VAV3	-2932
KRAS	-1382
GRAP2	-1305
PIK3CA	-717
SOS1	3385
LAT	4596
PIK3CB	6910
HRAS	8450
PLCG1	9033
VAV2	10056

---

REACTOME_SIGNALING_BY_EGFR_IN_CANCER

REACTOME_SIGNALING_BY_EGFR_IN_CANCER

	191
set	REACTOME_SIGNALING_BY_EGFR_IN_CANCER
setSize	25
pANOVA	0.00527
s.dist	-0.322
p.adjustANOVA	0.178

Top enriched genes

Top 20 genes

GeneID	Gene Rank
AREG	-10988
HBEGF	-10493
UBB	-9702
NRAS	-9202
EREG	-9027
UBC	-7974
SHC1	-7816
EPGN	-7315
GAB1	-6416
HSP90AA1	-6002
TGFA	-5777
PIK3R1	-5752
EGF	-5404
UBA52	-4361
BTC	-4048
GRB2	-2984
EGFR	-2625
RPS27A	-1544
KRAS	-1382
PIK3CA	-717

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
AREG	-10988
HBEGF	-10493
UBB	-9702
NRAS	-9202
EREG	-9027
UBC	-7974
SHC1	-7816
EPGN	-7315
GAB1	-6416
HSP90AA1	-6002
TGFA	-5777
PIK3R1	-5752
EGF	-5404
UBA52	-4361
BTC	-4048
GRB2	-2984
EGFR	-2625
RPS27A	-1544
KRAS	-1382
PIK3CA	-717
CBL	556
SOS1	3385
CDC37	8302
HRAS	8450
PLCG1	9033

---

REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY

REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY

	1591
set	REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY
setSize	33
pANOVA	0.00532
s.dist	-0.28
p.adjustANOVA	0.178

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS12	-10480
RPS25	-9996
RPS13	-8885
RPS26	-8630
RPS6	-8578
HNRNPA1	-8516
RPS28	-8280
FAU	-7687
RPS15A	-7332
RPSA	-6914
RPS3A	-6158
RPS24	-5677
RPS18	-5357
RPS20	-4837
EEF1A1	-4419
RPS10	-4220
RPS11	-4189
RPS5	-3903
RPS29	-3289
RPS16	-2594

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS12	-10480
RPS25	-9996
RPS13	-8885
RPS26	-8630
RPS6	-8578
HNRNPA1	-8516
RPS28	-8280
FAU	-7687
RPS15A	-7332
RPSA	-6914
RPS3A	-6158
RPS24	-5677
RPS18	-5357
RPS20	-4837
EEF1A1	-4419
RPS10	-4220
RPS11	-4189
RPS5	-3903
RPS29	-3289
RPS16	-2594
RPS15	-2337
RPS2	-1664
RPS27A	-1544
RPS8	-1326
RPS23	-1205
RPS21	-811
RPS9	-121
RPS7	1873
RPS27L	3876
RPS3	7084
RPS27	7437
RPS14	7712
RPS19	7721

---

REACTOME_MEIOTIC_RECOMBINATION

REACTOME_MEIOTIC_RECOMBINATION

	1433
set	REACTOME_MEIOTIC_RECOMBINATION
setSize	80
pANOVA	0.00539
s.dist	-0.18
p.adjustANOVA	0.178

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TEX15	-10470
H2AC20	-10322
RPA2	-9888
H2AX	-9652
RAD51	-9607
CDK4	-9528
H4C8	-9377
H3-3A	-9072
H2BC21	-9064
H2BC5	-8892
DMC1	-8807
H4C3	-8439
SPO11	-8316
H3C10	-7994
H2BC11	-7869
RBBP8	-7841
H2BC14	-7552
H2BC17	-7263
H2BC4	-7072
BLM	-7010

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TEX15	-10470.0
H2AC20	-10322.0
RPA2	-9888.0
H2AX	-9652.0
RAD51	-9607.0
CDK4	-9528.0
H4C8	-9377.0
H3-3A	-9072.0
H2BC21	-9064.0
H2BC5	-8892.0
DMC1	-8807.0
H4C3	-8439.0
SPO11	-8316.0
H3C10	-7994.0
H2BC11	-7869.0
RBBP8	-7841.0
H2BC14	-7552.0
H2BC17	-7263.0
H2BC4	-7072.0
BLM	-7010.0
H3-3B	-6937.0
RAD50	-6818.0
H3C2	-6790.0
H2AJ	-6672.0
H2BC13	-6590.0
H2AC8	-6445.0
H2AC7	-6250.5
H2BC7	-6250.5
H2AC6	-6100.0
CDK2	-6001.0
H2BC8	-5989.0
H2AC18	-5704.5
H2AC19	-5704.5
H3C4	-5557.0
H2AC14	-5481.0
H3C12	-5090.0
MLH1	-5056.0
BRCA2	-4876.0
RAD51C	-4272.0
H2BC6	-4207.0
H4C6	-4120.0
H3C11	-3817.0
H4C13	-3097.0
H2AZ2	-2221.0
H2AZ1	-1527.0
MND1	-1524.0
H4C2	-1183.0
NBN	-1104.0
H4C1	-737.0
H4C5	-618.0
H2BC15	-371.0
MRE11	-301.0
PSMC3IP	-269.0
H2BC1	-54.0
H2BC12	672.0
BRCA1	1391.0
H2AC4	2947.0
RPA3	3162.0
ATM	3236.0
H4C16	3253.0
MSH5	3603.0
TOP3A	3894.0
H3C1	4262.0
H2BC26	4643.0
RPA1	5108.0
H4C9	5218.0
H2BC9	5307.5
H3C7	5307.5
MLH3	5610.0
H4C4	6524.0
H3C6	6602.0
PRDM9	7259.0
H4C12	7358.0
H2BC3	8253.0
MSH4	8298.0
H3C3	9119.0
H2BC10	9234.0
H4C11	9599.0
H3C8	9880.0
H3-4	10284.0

---

REACTOME_INTERLEUKIN_2_SIGNALING

REACTOME_INTERLEUKIN_2_SIGNALING

	1399
set	REACTOME_INTERLEUKIN_2_SIGNALING
setSize	11
pANOVA	0.00548
s.dist	-0.484
p.adjustANOVA	0.178

Top enriched genes

Top 20 genes

GeneID	Gene Rank
JAK1	-9200
IL2	-9114
STAT5A	-8197
SHC1	-7816
IL2RA	-7427
SYK	-7342
LCK	-3915
IL2RB	-3400
STAT5B	-2385
PTK2B	-464
JAK3	218

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
JAK1	-9200
IL2	-9114
STAT5A	-8197
SHC1	-7816
IL2RA	-7427
SYK	-7342
LCK	-3915
IL2RB	-3400
STAT5B	-2385
PTK2B	-464
JAK3	218

---

Here is the session info with all the versions of packages used.

sessionInfo()

## R version 4.3.2 (2023-10-31)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.3 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3 
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so;  LAPACK version 3.10.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Etc/UTC
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.3.3                                      
##  [2] GGally_2.2.0                                       
##  [3] ggplot2_3.4.4                                      
##  [4] reshape2_1.4.4                                     
##  [5] gtools_3.9.5                                       
##  [6] tibble_3.2.1                                       
##  [7] dplyr_1.1.4                                        
##  [8] echarts4r_0.4.5                                    
##  [9] png_0.1-8                                          
## [10] gridExtra_2.3                                      
## [11] missMethyl_1.36.0                                  
## [12] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.1 
## [13] beeswarm_0.4.0                                     
## [14] kableExtra_1.3.4                                   
## [15] gplots_3.1.3                                       
## [16] mitch_1.15.0                                       
## [17] tictoc_1.2                                         
## [18] HGNChelper_0.8.1                                   
## [19] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [20] IlluminaHumanMethylation450kmanifest_0.4.0         
## [21] minfi_1.48.0                                       
## [22] bumphunter_1.44.0                                  
## [23] locfit_1.5-9.8                                     
## [24] iterators_1.0.14                                   
## [25] foreach_1.5.2                                      
## [26] Biostrings_2.70.1                                  
## [27] XVector_0.42.0                                     
## [28] SummarizedExperiment_1.32.0                        
## [29] Biobase_2.62.0                                     
## [30] MatrixGenerics_1.14.0                              
## [31] matrixStats_1.2.0                                  
## [32] GenomicRanges_1.54.1                               
## [33] GenomeInfoDb_1.38.2                                
## [34] IRanges_2.36.0                                     
## [35] S4Vectors_0.40.2                                   
## [36] BiocGenerics_0.48.1                                
## [37] eulerr_7.0.0                                       
## [38] limma_3.58.1                                       
## 
## loaded via a namespace (and not attached):
##   [1] splines_4.3.2             later_1.3.2              
##   [3] BiocIO_1.12.0             bitops_1.0-7             
##   [5] filelock_1.0.3            preprocessCore_1.64.0    
##   [7] XML_3.99-0.16             lifecycle_1.0.4          
##   [9] lattice_0.22-5            MASS_7.3-60              
##  [11] base64_2.0.1              scrime_1.3.5             
##  [13] magrittr_2.0.3            sass_0.4.8               
##  [15] rmarkdown_2.25            jquerylib_0.1.4          
##  [17] yaml_2.3.8                httpuv_1.6.13            
##  [19] doRNG_1.8.6               askpass_1.2.0            
##  [21] DBI_1.1.3                 RColorBrewer_1.1-3       
##  [23] abind_1.4-5               zlibbioc_1.48.0          
##  [25] rvest_1.0.3               quadprog_1.5-8           
##  [27] purrr_1.0.2               RCurl_1.98-1.13          
##  [29] rappdirs_0.3.3            GenomeInfoDbData_1.2.11  
##  [31] genefilter_1.84.0         annotate_1.80.0          
##  [33] svglite_2.1.3             DelayedMatrixStats_1.24.0
##  [35] codetools_0.2-19          DelayedArray_0.28.0      
##  [37] xml2_1.3.6                tidyselect_1.2.0         
##  [39] beanplot_1.3.1            BiocFileCache_2.10.1     
##  [41] webshot_0.5.5             illuminaio_0.44.0        
##  [43] GenomicAlignments_1.38.0  jsonlite_1.8.8           
##  [45] multtest_2.58.0           ellipsis_0.3.2           
##  [47] survival_3.5-7            systemfonts_1.0.5        
##  [49] tools_4.3.2               progress_1.2.3           
##  [51] Rcpp_1.0.11               glue_1.6.2               
##  [53] SparseArray_1.2.2         xfun_0.41                
##  [55] HDF5Array_1.30.0          withr_2.5.2              
##  [57] fastmap_1.1.1             rhdf5filters_1.14.1      
##  [59] fansi_1.0.6               openssl_2.1.1            
##  [61] caTools_1.18.2            digest_0.6.33            
##  [63] R6_2.5.1                  mime_0.12                
##  [65] colorspace_2.1-0          biomaRt_2.58.0           
##  [67] RSQLite_2.3.4             utf8_1.2.4               
##  [69] tidyr_1.3.0               generics_0.1.3           
##  [71] data.table_1.14.10        rtracklayer_1.62.0       
##  [73] prettyunits_1.2.0         httr_1.4.7               
##  [75] htmlwidgets_1.6.4         S4Arrays_1.2.0           
##  [77] ggstats_0.5.1             pkgconfig_2.0.3          
##  [79] gtable_0.3.4              blob_1.2.4               
##  [81] siggenes_1.76.0           htmltools_0.5.7          
##  [83] scales_1.3.0              rstudioapi_0.15.0        
##  [85] knitr_1.45                tzdb_0.4.0               
##  [87] rjson_0.2.21              nlme_3.1-163             
##  [89] curl_5.2.0                org.Hs.eg.db_3.18.0      
##  [91] cachem_1.0.8              rhdf5_2.46.1             
##  [93] stringr_1.5.1             KernSmooth_2.23-22       
##  [95] AnnotationDbi_1.64.1      restfulr_0.0.15          
##  [97] GEOquery_2.70.0           pillar_1.9.0             
##  [99] grid_4.3.2                reshape_0.8.9            
## [101] vctrs_0.6.5               promises_1.2.1           
## [103] dbplyr_2.4.0              xtable_1.8-4             
## [105] evaluate_0.23             readr_2.1.4              
## [107] GenomicFeatures_1.54.1    cli_3.6.2                
## [109] compiler_4.3.2            Rsamtools_2.18.0         
## [111] rlang_1.1.2               crayon_1.5.2             
## [113] rngtools_1.5.2            nor1mix_1.3-2            
## [115] mclust_6.0.1              plyr_1.8.9               
## [117] stringi_1.8.3             viridisLite_0.4.2        
## [119] BiocParallel_1.36.0       munsell_0.5.0            
## [121] Matrix_1.6-1.1            hms_1.1.3                
## [123] sparseMatrixStats_1.14.0  bit64_4.0.5              
## [125] Rhdf5lib_1.24.1           KEGGREST_1.42.0          
## [127] statmod_1.5.0             shiny_1.8.0              
## [129] highr_0.10                memoise_2.0.1            
## [131] bslib_0.6.1               bit_4.0.5

END of report