Mitch Report
Antony Kaspi & Mark Ziemann
date generated: 2024-01-18
Background
Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch
Input profiles
Here is the first few lines of the input profile.
| x | |
|---|---|
| A1BG | -0.0040420 |
| A1BG-AS1 | -0.0081251 |
| A1CF | 0.0156203 |
| A2M | -0.0025244 |
| A2M-AS1 | -0.0309060 |
| A2ML1 | -0.0001159 |
Here are some metrics about the input data profile:
| Profile metrics | |
|---|---|
| num_genesets | 1654 |
| num_genes_in_profile | 22007 |
| duplicated_genes_present | 0 |
| num_profile_genes_in_sets | 10383 |
| num_profile_genes_not_in_sets | 11624 |
Here is a plot of the input profiles. Note the dynamic ranges.
Here is the contour plot of the profile including all detected genes.
Input genesets
Here are some metrics about the gene sets used:
GMT file of genesets: c2.cp.reactome.v2023.1.Hs.symbols.gmt| Gene sets metrics | |
|---|---|
| num_genesets | 1654 |
| num_genesets_excluded | 365 |
| num_genesets_included | 1289 |
Differential pathway expression
Interactive enrichment scatterplot
Significance is calculated by -log10(p-value). All points shown are
FDR<0.05.
Significance is calculated by -log10(p-value). Top N sets shown
irrespective of FDR.
Results table
Top N= 50 gene sets
## Warning in kable_styling(., "hover", full_width = FALSE): Please specify format
## in kable. kableExtra can customize either HTML or LaTeX outputs. See
## https://haozhu233.github.io/kableExtra/ for details.| set | setSize | pANOVA | s.dist | p.adjustANOVA |
|---|---|---|---|---|
| REACTOME TRANSLATION | 278 | 3.79e-22 | 0.337 | 5.52e-19 |
| REACTOME METABOLISM OF RNA | 675 | 6.72e-22 | 0.217 | 5.52e-19 |
| REACTOME RNA POLYMERASE II TRANSCRIPTION | 1336 | 5.37e-21 | 0.153 | 2.94e-18 |
| REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | 105 | 6.47e-15 | 0.440 | 2.66e-12 |
| REACTOME CELLULAR RESPONSES TO STIMULI | 779 | 8.55e-15 | 0.163 | 2.70e-12 |
| REACTOME EUKARYOTIC TRANSLATION INITIATION | 110 | 9.86e-15 | 0.427 | 2.70e-12 |
| REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS | 161 | 1.22e-14 | 0.352 | 2.87e-12 |
| REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY | 94 | 6.66e-14 | 0.447 | 1.37e-11 |
| REACTOME EUKARYOTIC TRANSLATION ELONGATION | 87 | 1.92e-13 | 0.456 | 3.50e-11 |
| REACTOME NONSENSE MEDIATED DECAY NMD | 107 | 1.14e-12 | 0.398 | 1.88e-10 |
| REACTOME SENSORY PERCEPTION | 555 | 6.12e-12 | -0.171 | 9.14e-10 |
| REACTOME SIGNALING BY ROBO RECEPTORS | 206 | 4.62e-11 | 0.266 | 6.32e-09 |
| REACTOME INFLUENZA INFECTION | 149 | 9.77e-11 | 0.307 | 1.23e-08 |
| REACTOME INFECTIOUS DISEASE | 910 | 1.26e-10 | 0.126 | 1.48e-08 |
| REACTOME SELENOAMINO ACID METABOLISM | 108 | 1.46e-10 | 0.357 | 1.59e-08 |
| REACTOME CELLULAR RESPONSE TO STARVATION | 147 | 3.27e-10 | 0.300 | 3.35e-08 |
| REACTOME CELL CYCLE | 666 | 7.22e-10 | 0.140 | 6.97e-08 |
| REACTOME RRNA PROCESSING | 192 | 1.07e-09 | 0.255 | 9.78e-08 |
| REACTOME CELL CYCLE MITOTIC | 539 | 2.81e-08 | 0.140 | 2.43e-06 |
| REACTOME DNA REPLICATION PRE INITIATION | 150 | 3.00e-08 | 0.262 | 2.46e-06 |
| REACTOME DNA REPLICATION | 178 | 5.43e-08 | 0.236 | 4.25e-06 |
| REACTOME MITOCHONDRIAL TRANSLATION | 93 | 1.34e-07 | 0.316 | 9.91e-06 |
| REACTOME CELL CYCLE CHECKPOINTS | 284 | 1.39e-07 | 0.182 | 9.91e-06 |
| REACTOME SARS COV 1 HOST INTERACTIONS | 92 | 3.64e-07 | 0.307 | 2.49e-05 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS | 121 | 4.35e-07 | 0.266 | 2.86e-05 |
| REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | 111 | 5.62e-07 | 0.275 | 3.48e-05 |
| REACTOME RNA POLYMERASE I PROMOTER ESCAPE | 83 | 5.72e-07 | 0.317 | 3.48e-05 |
| REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT | 159 | 7.02e-07 | 0.228 | 4.12e-05 |
| REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | 263 | 7.31e-07 | 0.177 | 4.14e-05 |
| REACTOME G2 M CHECKPOINTS | 162 | 7.68e-07 | 0.225 | 4.20e-05 |
| REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY | 33 | 1.33e-06 | 0.486 | 7.06e-05 |
| REACTOME CHROMOSOME MAINTENANCE | 130 | 1.46e-06 | 0.245 | 7.51e-05 |
| REACTOME EXTRACELLULAR MATRIX ORGANIZATION | 291 | 1.51e-06 | -0.164 | 7.52e-05 |
| REACTOME OLFACTORY SIGNALING PATHWAY | 348 | 1.79e-06 | -0.149 | 8.65e-05 |
| REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | 86 | 2.65e-06 | 0.293 | 1.24e-04 |
| REACTOME PROTEIN LOCALIZATION | 153 | 2.85e-06 | 0.219 | 1.30e-04 |
| REACTOME FORMATION OF THE CORNIFIED ENVELOPE | 125 | 3.51e-06 | -0.240 | 1.56e-04 |
| REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION | 84 | 3.76e-06 | 0.292 | 1.59e-04 |
| REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | 53 | 3.77e-06 | 0.367 | 1.59e-04 |
| REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | 353 | 4.33e-06 | 0.142 | 1.78e-04 |
| REACTOME M PHASE | 398 | 5.79e-06 | 0.132 | 2.32e-04 |
| REACTOME SARS COV 1 INFECTION | 136 | 5.96e-06 | 0.225 | 2.33e-04 |
| REACTOME MEIOTIC RECOMBINATION | 80 | 7.44e-06 | 0.290 | 2.84e-04 |
| REACTOME TCR SIGNALING | 113 | 9.38e-06 | 0.241 | 3.42e-04 |
| REACTOME ANTIGEN PROCESSING CROSS PRESENTATION | 98 | 9.38e-06 | 0.259 | 3.42e-04 |
| REACTOME PERK REGULATES GENE EXPRESSION | 31 | 1.02e-05 | 0.458 | 3.64e-04 |
| REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21 | 59 | 1.15e-05 | 0.330 | 4.00e-04 |
| REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION | 100 | 1.17e-05 | 0.254 | 4.00e-04 |
| REACTOME UCH PROTEINASES | 99 | 1.28e-05 | 0.254 | 4.29e-04 |
| REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY | 46 | 1.41e-05 | 0.370 | 4.58e-04 |
Results (complete table)
Click HERE to show results for all gene sets
| set | setSize | pANOVA | s.dist | p.adjustANOVA |
|---|---|---|---|---|
| REACTOME TRANSLATION | 278 | 3.79e-22 | 3.37e-01 | 5.52e-19 |
| REACTOME METABOLISM OF RNA | 675 | 6.72e-22 | 2.17e-01 | 5.52e-19 |
| REACTOME RNA POLYMERASE II TRANSCRIPTION | 1336 | 5.37e-21 | 1.53e-01 | 2.94e-18 |
| REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | 105 | 6.47e-15 | 4.40e-01 | 2.66e-12 |
| REACTOME CELLULAR RESPONSES TO STIMULI | 779 | 8.55e-15 | 1.63e-01 | 2.70e-12 |
| REACTOME EUKARYOTIC TRANSLATION INITIATION | 110 | 9.86e-15 | 4.27e-01 | 2.70e-12 |
| REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS | 161 | 1.22e-14 | 3.52e-01 | 2.87e-12 |
| REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY | 94 | 6.66e-14 | 4.47e-01 | 1.37e-11 |
| REACTOME EUKARYOTIC TRANSLATION ELONGATION | 87 | 1.92e-13 | 4.56e-01 | 3.50e-11 |
| REACTOME NONSENSE MEDIATED DECAY NMD | 107 | 1.14e-12 | 3.98e-01 | 1.88e-10 |
| REACTOME SENSORY PERCEPTION | 555 | 6.12e-12 | -1.71e-01 | 9.14e-10 |
| REACTOME SIGNALING BY ROBO RECEPTORS | 206 | 4.62e-11 | 2.66e-01 | 6.32e-09 |
| REACTOME INFLUENZA INFECTION | 149 | 9.77e-11 | 3.07e-01 | 1.23e-08 |
| REACTOME INFECTIOUS DISEASE | 910 | 1.26e-10 | 1.26e-01 | 1.48e-08 |
| REACTOME SELENOAMINO ACID METABOLISM | 108 | 1.46e-10 | 3.57e-01 | 1.59e-08 |
| REACTOME CELLULAR RESPONSE TO STARVATION | 147 | 3.27e-10 | 3.00e-01 | 3.35e-08 |
| REACTOME CELL CYCLE | 666 | 7.22e-10 | 1.40e-01 | 6.97e-08 |
| REACTOME RRNA PROCESSING | 192 | 1.07e-09 | 2.55e-01 | 9.78e-08 |
| REACTOME CELL CYCLE MITOTIC | 539 | 2.81e-08 | 1.40e-01 | 2.43e-06 |
| REACTOME DNA REPLICATION PRE INITIATION | 150 | 3.00e-08 | 2.62e-01 | 2.46e-06 |
| REACTOME DNA REPLICATION | 178 | 5.43e-08 | 2.36e-01 | 4.25e-06 |
| REACTOME MITOCHONDRIAL TRANSLATION | 93 | 1.34e-07 | 3.16e-01 | 9.91e-06 |
| REACTOME CELL CYCLE CHECKPOINTS | 284 | 1.39e-07 | 1.82e-01 | 9.91e-06 |
| REACTOME SARS COV 1 HOST INTERACTIONS | 92 | 3.64e-07 | 3.07e-01 | 2.49e-05 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS | 121 | 4.35e-07 | 2.66e-01 | 2.86e-05 |
| REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | 111 | 5.62e-07 | 2.75e-01 | 3.48e-05 |
| REACTOME RNA POLYMERASE I PROMOTER ESCAPE | 83 | 5.72e-07 | 3.17e-01 | 3.48e-05 |
| REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT | 159 | 7.02e-07 | 2.28e-01 | 4.12e-05 |
| REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | 263 | 7.31e-07 | 1.77e-01 | 4.14e-05 |
| REACTOME G2 M CHECKPOINTS | 162 | 7.68e-07 | 2.25e-01 | 4.20e-05 |
| REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY | 33 | 1.33e-06 | 4.86e-01 | 7.06e-05 |
| REACTOME CHROMOSOME MAINTENANCE | 130 | 1.46e-06 | 2.45e-01 | 7.51e-05 |
| REACTOME EXTRACELLULAR MATRIX ORGANIZATION | 291 | 1.51e-06 | -1.64e-01 | 7.52e-05 |
| REACTOME OLFACTORY SIGNALING PATHWAY | 348 | 1.79e-06 | -1.49e-01 | 8.65e-05 |
| REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | 86 | 2.65e-06 | 2.93e-01 | 1.24e-04 |
| REACTOME PROTEIN LOCALIZATION | 153 | 2.85e-06 | 2.19e-01 | 1.30e-04 |
| REACTOME FORMATION OF THE CORNIFIED ENVELOPE | 125 | 3.51e-06 | -2.40e-01 | 1.56e-04 |
| REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION | 84 | 3.76e-06 | 2.92e-01 | 1.59e-04 |
| REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | 53 | 3.77e-06 | 3.67e-01 | 1.59e-04 |
| REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | 353 | 4.33e-06 | 1.42e-01 | 1.78e-04 |
| REACTOME M PHASE | 398 | 5.79e-06 | 1.32e-01 | 2.32e-04 |
| REACTOME SARS COV 1 INFECTION | 136 | 5.96e-06 | 2.25e-01 | 2.33e-04 |
| REACTOME MEIOTIC RECOMBINATION | 80 | 7.44e-06 | 2.90e-01 | 2.84e-04 |
| REACTOME TCR SIGNALING | 113 | 9.38e-06 | 2.41e-01 | 3.42e-04 |
| REACTOME ANTIGEN PROCESSING CROSS PRESENTATION | 98 | 9.38e-06 | 2.59e-01 | 3.42e-04 |
| REACTOME PERK REGULATES GENE EXPRESSION | 31 | 1.02e-05 | 4.58e-01 | 3.64e-04 |
| REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21 | 59 | 1.15e-05 | 3.30e-01 | 4.00e-04 |
| REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION | 100 | 1.17e-05 | 2.54e-01 | 4.00e-04 |
| REACTOME UCH PROTEINASES | 99 | 1.28e-05 | 2.54e-01 | 4.29e-04 |
| REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY | 46 | 1.41e-05 | 3.70e-01 | 4.58e-04 |
| REACTOME RESPIRATORY ELECTRON TRANSPORT | 90 | 1.44e-05 | 2.65e-01 | 4.58e-04 |
| REACTOME ORC1 REMOVAL FROM CHROMATIN | 70 | 1.45e-05 | 3.00e-01 | 4.58e-04 |
| REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION | 145 | 1.58e-05 | 2.08e-01 | 4.82e-04 |
| REACTOME TELOMERE MAINTENANCE | 106 | 1.58e-05 | 2.43e-01 | 4.82e-04 |
| REACTOME MRNA SPLICING | 197 | 1.72e-05 | 1.78e-01 | 5.13e-04 |
| REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP | 104 | 1.88e-05 | 2.43e-01 | 5.52e-04 |
| REACTOME APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS | 87 | 2.26e-05 | 2.63e-01 | 6.47e-04 |
| REACTOME S PHASE | 159 | 2.28e-05 | 1.95e-01 | 6.47e-04 |
| REACTOME SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE | 91 | 2.60e-05 | 2.55e-01 | 7.20e-04 |
| REACTOME SYNTHESIS OF DNA | 119 | 2.63e-05 | 2.23e-01 | 7.20e-04 |
| REACTOME SEPARATION OF SISTER CHROMATIDS | 184 | 2.93e-05 | 1.79e-01 | 7.88e-04 |
| REACTOME KERATINIZATION | 210 | 3.17e-05 | -1.67e-01 | 8.29e-04 |
| REACTOME DIGESTION AND ABSORPTION | 22 | 3.18e-05 | -5.12e-01 | 8.29e-04 |
| REACTOME VISUAL PHOTOTRANSDUCTION | 93 | 3.32e-05 | -2.49e-01 | 8.52e-04 |
| REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS | 60 | 3.48e-05 | 3.09e-01 | 8.79e-04 |
| REACTOME MITOTIC METAPHASE AND ANAPHASE | 228 | 3.87e-05 | 1.58e-01 | 9.56e-04 |
| REACTOME AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA | 54 | 3.90e-05 | 3.24e-01 | 9.56e-04 |
| REACTOME MITOCHONDRIAL PROTEIN IMPORT | 58 | 4.20e-05 | 3.11e-01 | 1.01e-03 |
| REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS | 113 | 4.59e-05 | 2.22e-01 | 1.08e-03 |
| REACTOME STABILIZATION OF P53 | 56 | 4.59e-05 | 3.15e-01 | 1.08e-03 |
| REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | 134 | 5.02e-05 | -2.03e-01 | 1.16e-03 |
| REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION | 98 | 5.25e-05 | 2.36e-01 | 1.20e-03 |
| REACTOME TRANSPORT OF SMALL MOLECULES | 697 | 5.93e-05 | -8.92e-02 | 1.32e-03 |
| REACTOME THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT | 77 | 5.95e-05 | 2.65e-01 | 1.32e-03 |
| REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | 66 | 6.57e-05 | 2.84e-01 | 1.44e-03 |
| REACTOME MITOTIC G2 G2 M PHASES | 194 | 6.78e-05 | 1.66e-01 | 1.46e-03 |
| REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | 73 | 8.03e-05 | 2.67e-01 | 1.71e-03 |
| REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE | 63 | 8.35e-05 | 2.87e-01 | 1.74e-03 |
| REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH | 62 | 8.36e-05 | -2.89e-01 | 1.74e-03 |
| REACTOME HIV INFECTION | 223 | 8.95e-05 | 1.52e-01 | 1.84e-03 |
| REACTOME RNA POLYMERASE I TRANSCRIPTION | 102 | 9.13e-05 | 2.24e-01 | 1.85e-03 |
| REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM | 688 | 1.04e-04 | 8.68e-02 | 2.09e-03 |
| REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS | 83 | 1.09e-04 | 2.46e-01 | 2.16e-03 |
| REACTOME CELLULAR SENESCENCE | 189 | 1.13e-04 | 1.63e-01 | 2.21e-03 |
| REACTOME MEIOSIS | 110 | 1.16e-04 | 2.13e-01 | 2.24e-03 |
| REACTOME ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS | 27 | 1.28e-04 | 4.26e-01 | 2.44e-03 |
| REACTOME NEGATIVE REGULATION OF NOTCH4 SIGNALING | 53 | 1.43e-04 | 3.02e-01 | 2.67e-03 |
| REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY | 72 | 1.43e-04 | 2.59e-01 | 2.67e-03 |
| REACTOME NUCLEAR EVENTS MEDIATED BY NFE2L2 | 77 | 1.48e-04 | 2.50e-01 | 2.73e-03 |
| REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION | 62 | 1.57e-04 | 2.78e-01 | 2.86e-03 |
| REACTOME ADAPTIVE IMMUNE SYSTEM | 729 | 1.78e-04 | 8.15e-02 | 3.21e-03 |
| REACTOME ION CHANNEL TRANSPORT | 172 | 1.97e-04 | -1.65e-01 | 3.51e-03 |
| REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION | 60 | 2.09e-04 | 2.77e-01 | 3.70e-03 |
| REACTOME PROGRAMMED CELL DEATH | 204 | 2.47e-04 | 1.49e-01 | 4.32e-03 |
| REACTOME MAPK6 MAPK4 SIGNALING | 91 | 2.54e-04 | 2.22e-01 | 4.38e-03 |
| REACTOME NGF STIMULATED TRANSCRIPTION | 38 | 2.73e-04 | 3.41e-01 | 4.67e-03 |
| REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION | 138 | 2.81e-04 | 1.79e-01 | 4.75e-03 |
| REACTOME TNFR2 NON CANONICAL NF KB PATHWAY | 96 | 2.91e-04 | 2.14e-01 | 4.88e-03 |
| REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 | 54 | 3.04e-04 | 2.84e-01 | 5.03e-03 |
| REACTOME HEDGEHOG LIGAND BIOGENESIS | 64 | 3.06e-04 | 2.61e-01 | 5.03e-03 |
| REACTOME DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING | 61 | 3.12e-04 | 2.67e-01 | 5.03e-03 |
| REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS | 100 | 3.12e-04 | 2.09e-01 | 5.03e-03 |
| REACTOME DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE | 76 | 3.18e-04 | 2.39e-01 | 5.06e-03 |
| REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT | 222 | 3.23e-04 | 1.40e-01 | 5.10e-03 |
| REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION | 89 | 3.27e-04 | 2.20e-01 | 5.11e-03 |
| REACTOME STIMULI SENSING CHANNELS | 100 | 3.44e-04 | -2.07e-01 | 5.33e-03 |
| REACTOME TRANSCRIPTIONAL REGULATION BY TP53 | 351 | 3.49e-04 | 1.11e-01 | 5.34e-03 |
| REACTOME CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY | 84 | 3.51e-04 | 2.26e-01 | 5.34e-03 |
| REACTOME CELLULAR RESPONSE TO HYPOXIA | 74 | 3.59e-04 | 2.40e-01 | 5.41e-03 |
| REACTOME DEGRADATION OF GLI1 BY THE PROTEASOME | 59 | 3.66e-04 | 2.68e-01 | 5.46e-03 |
| REACTOME G1 S DNA DAMAGE CHECKPOINTS | 67 | 3.82e-04 | 2.51e-01 | 5.65e-03 |
| REACTOME MET ACTIVATES PTK2 SIGNALING | 30 | 4.12e-04 | -3.73e-01 | 6.00e-03 |
| REACTOME INNATE IMMUNE SYSTEM | 1002 | 4.13e-04 | 6.59e-02 | 6.00e-03 |
| REACTOME SENSORY PERCEPTION OF TASTE | 47 | 4.50e-04 | -2.96e-01 | 6.48e-03 |
| REACTOME SARS COV 2 HOST INTERACTIONS | 191 | 5.36e-04 | 1.45e-01 | 7.65e-03 |
| REACTOME DIGESTION | 17 | 5.60e-04 | -4.83e-01 | 7.92e-03 |
| REACTOME RNA POLYMERASE I TRANSCRIPTION TERMINATION | 30 | 5.77e-04 | 3.63e-01 | 8.09e-03 |
| REACTOME REGULATED NECROSIS | 57 | 5.92e-04 | 2.63e-01 | 8.24e-03 |
| REACTOME INTERLEUKIN 12 FAMILY SIGNALING | 53 | 6.10e-04 | 2.72e-01 | 8.42e-03 |
| REACTOME BASE EXCISION REPAIR | 87 | 6.22e-04 | 2.12e-01 | 8.51e-03 |
| REACTOME CALNEXIN CALRETICULIN CYCLE | 26 | 6.71e-04 | 3.85e-01 | 9.10e-03 |
| REACTOME METABOLISM OF POLYAMINES | 56 | 6.87e-04 | 2.62e-01 | 9.22e-03 |
| REACTOME HOST INTERACTIONS OF HIV FACTORS | 127 | 6.91e-04 | 1.74e-01 | 9.22e-03 |
| REACTOME DNA REPAIR | 321 | 6.97e-04 | 1.10e-01 | 9.22e-03 |
| REACTOME AMYLOID FIBER FORMATION | 102 | 7.12e-04 | 1.94e-01 | 9.22e-03 |
| REACTOME DEGRADATION OF AXIN | 54 | 7.13e-04 | 2.66e-01 | 9.22e-03 |
| REACTOME SIGNALING BY INTERLEUKINS | 444 | 7.13e-04 | 9.37e-02 | 9.22e-03 |
| REACTOME SARS COV INFECTIONS | 392 | 7.82e-04 | 9.88e-02 | 9.99e-03 |
| REACTOME UB SPECIFIC PROCESSING PROTEASES | 187 | 7.85e-04 | 1.42e-01 | 9.99e-03 |
| REACTOME PROTEIN UBIQUITINATION | 76 | 8.08e-04 | 2.22e-01 | 1.02e-02 |
| REACTOME BASE EXCISION REPAIR AP SITE FORMATION | 59 | 9.02e-04 | 2.50e-01 | 1.13e-02 |
| REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3 | 59 | 9.24e-04 | 2.49e-01 | 1.15e-02 |
| REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS | 63 | 9.60e-04 | 2.41e-01 | 1.19e-02 |
| REACTOME RNA POLYMERASE II TRANSCRIBES SNRNA GENES | 77 | 9.75e-04 | 2.17e-01 | 1.20e-02 |
| REACTOME SIGNALING BY THE B CELL RECEPTOR BCR | 106 | 1.08e-03 | 1.84e-01 | 1.30e-02 |
| REACTOME NEGATIVE REGULATION OF FLT3 | 15 | 1.08e-03 | 4.88e-01 | 1.30e-02 |
| REACTOME COLLAGEN CHAIN TRIMERIZATION | 42 | 1.10e-03 | -2.91e-01 | 1.32e-02 |
| REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT | 236 | 1.14e-03 | -1.23e-01 | 1.36e-02 |
| REACTOME REGULATION OF RUNX3 EXPRESSION AND ACTIVITY | 54 | 1.20e-03 | 2.55e-01 | 1.42e-02 |
| REACTOME DISEASES OF PROGRAMMED CELL DEATH | 96 | 1.27e-03 | 1.90e-01 | 1.49e-02 |
| REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1 | 229 | 1.29e-03 | 1.23e-01 | 1.50e-02 |
| REACTOME OXIDATIVE STRESS INDUCED SENESCENCE | 118 | 1.32e-03 | 1.71e-01 | 1.52e-02 |
| REACTOME CONDENSATION OF PROPHASE CHROMOSOMES | 66 | 1.32e-03 | 2.28e-01 | 1.52e-02 |
| REACTOME HCMV EARLY EVENTS | 128 | 1.35e-03 | 1.64e-01 | 1.54e-02 |
| REACTOME PROCESSING OF DNA DOUBLE STRAND BREAK ENDS | 93 | 1.48e-03 | 1.91e-01 | 1.68e-02 |
| REACTOME TRANSCRIPTIONAL REGULATION BY RUNX2 | 117 | 1.54e-03 | 1.69e-01 | 1.73e-02 |
| REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION | 361 | 1.58e-03 | 9.68e-02 | 1.76e-02 |
| REACTOME SIGNALING BY NOTCH4 | 80 | 1.60e-03 | 2.04e-01 | 1.78e-02 |
| REACTOME G2 M DNA DAMAGE CHECKPOINT | 90 | 1.65e-03 | 1.92e-01 | 1.80e-02 |
| REACTOME COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES | 65 | 1.66e-03 | -2.26e-01 | 1.80e-02 |
| REACTOME DEUBIQUITINATION | 260 | 1.66e-03 | 1.13e-01 | 1.80e-02 |
| REACTOME E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS | 58 | 1.73e-03 | 2.38e-01 | 1.86e-02 |
| REACTOME PINK1 PRKN MEDIATED MITOPHAGY | 22 | 1.77e-03 | 3.85e-01 | 1.90e-02 |
| REACTOME HCMV INFECTION | 152 | 1.78e-03 | 1.47e-01 | 1.90e-02 |
| REACTOME FCERI MEDIATED NF KB ACTIVATION | 78 | 1.87e-03 | 2.04e-01 | 1.98e-02 |
| REACTOME ECM PROTEOGLYCANS | 73 | 1.90e-03 | -2.10e-01 | 2.00e-02 |
| REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES | 39 | 1.93e-03 | 2.87e-01 | 2.02e-02 |
| REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM | 23 | 2.06e-03 | 3.71e-01 | 2.14e-02 |
| REACTOME ESTROGEN DEPENDENT GENE EXPRESSION | 140 | 2.10e-03 | 1.51e-01 | 2.17e-02 |
| REACTOME COLLAGEN DEGRADATION | 61 | 2.13e-03 | -2.27e-01 | 2.19e-02 |
| REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE | 35 | 2.40e-03 | 2.96e-01 | 2.44e-02 |
| REACTOME ENDOSOMAL VACUOLAR PATHWAY | 11 | 2.41e-03 | 5.28e-01 | 2.44e-02 |
| REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE | 52 | 2.42e-03 | 2.43e-01 | 2.44e-02 |
| REACTOME REGULATION OF RAS BY GAPS | 66 | 2.51e-03 | 2.15e-01 | 2.51e-02 |
| REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS | 55 | 2.52e-03 | -2.35e-01 | 2.51e-02 |
| REACTOME SIGNALING BY NUCLEAR RECEPTORS | 283 | 2.55e-03 | 1.04e-01 | 2.51e-02 |
| REACTOME HCMV LATE EVENTS | 110 | 2.55e-03 | 1.67e-01 | 2.51e-02 |
| REACTOME SARS COV 2 INFECTION | 281 | 2.75e-03 | 1.04e-01 | 2.69e-02 |
| REACTOME FOLDING OF ACTIN BY CCT TRIC | 10 | 2.85e-03 | 5.45e-01 | 2.77e-02 |
| REACTOME NCAM1 INTERACTIONS | 41 | 2.92e-03 | -2.69e-01 | 2.82e-02 |
| REACTOME RECYCLING OF EIF2 GDP | 7 | 2.96e-03 | 6.49e-01 | 2.84e-02 |
| REACTOME ER QUALITY CONTROL COMPARTMENT ERQC | 21 | 3.00e-03 | 3.74e-01 | 2.87e-02 |
| REACTOME FLT3 SIGNALING BY CBL MUTANTS | 7 | 3.15e-03 | 6.44e-01 | 2.99e-02 |
| REACTOME NEUTROPHIL DEGRANULATION | 460 | 3.21e-03 | 8.02e-02 | 3.03e-02 |
| REACTOME SIGNALING BY WNT | 318 | 3.31e-03 | 9.58e-02 | 3.10e-02 |
| REACTOME PRC2 METHYLATES HISTONES AND DNA | 65 | 3.42e-03 | 2.10e-01 | 3.19e-02 |
| REACTOME HOMOLOGY DIRECTED REPAIR | 132 | 3.45e-03 | 1.47e-01 | 3.20e-02 |
| REACTOME CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS | 100 | 3.49e-03 | 1.69e-01 | 3.22e-02 |
| REACTOME INITIAL TRIGGERING OF COMPLEMENT | 21 | 3.53e-03 | -3.68e-01 | 3.24e-02 |
| REACTOME SIGNALING BY VEGF | 102 | 3.62e-03 | -1.67e-01 | 3.30e-02 |
| REACTOME COLLAGEN FORMATION | 88 | 3.76e-03 | -1.79e-01 | 3.41e-02 |
| REACTOME FC EPSILON RECEPTOR FCERI SIGNALING | 127 | 3.79e-03 | 1.49e-01 | 3.42e-02 |
| REACTOME ACYL CHAIN REMODELLING OF PC | 27 | 3.85e-03 | -3.21e-01 | 3.45e-02 |
| REACTOME HDACS DEACETYLATE HISTONES | 85 | 3.88e-03 | 1.81e-01 | 3.46e-02 |
| REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | 16 | 3.97e-03 | 4.16e-01 | 3.52e-02 |
| REACTOME ABC TRANSPORTER DISORDERS | 76 | 4.09e-03 | 1.90e-01 | 3.61e-02 |
| REACTOME DEVELOPMENTAL BIOLOGY | 1115 | 4.15e-03 | 5.09e-02 | 3.65e-02 |
| REACTOME DNA METHYLATION | 58 | 4.24e-03 | 2.17e-01 | 3.71e-02 |
| REACTOME HEDGEHOG ON STATE | 85 | 4.28e-03 | 1.79e-01 | 3.72e-02 |
| REACTOME NEDDYLATION | 235 | 4.39e-03 | 1.08e-01 | 3.79e-02 |
| REACTOME DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX | 83 | 4.47e-03 | 1.81e-01 | 3.83e-02 |
| REACTOME APOPTOSIS | 173 | 4.48e-03 | 1.25e-01 | 3.83e-02 |
| REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION | 68 | 4.51e-03 | 1.99e-01 | 3.83e-02 |
| REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES | 14 | 4.58e-03 | -4.38e-01 | 3.88e-02 |
| REACTOME ESR MEDIATED SIGNALING | 210 | 4.62e-03 | 1.13e-01 | 3.89e-02 |
| REACTOME RIPK1 MEDIATED REGULATED NECROSIS | 30 | 4.75e-03 | 2.98e-01 | 3.98e-02 |
| REACTOME DEGRADATION OF DVL | 56 | 4.79e-03 | 2.18e-01 | 3.99e-02 |
| REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE GIP | 12 | 4.82e-03 | 4.70e-01 | 4.00e-02 |
| REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS | 418 | 4.93e-03 | 8.02e-02 | 4.07e-02 |
| REACTOME INTERLEUKIN 1 SIGNALING | 110 | 5.13e-03 | 1.54e-01 | 4.21e-02 |
| REACTOME SIGNALING BY NOTCH | 234 | 5.16e-03 | 1.06e-01 | 4.21e-02 |
| REACTOME THE PHOTOTRANSDUCTION CASCADE | 32 | 5.28e-03 | -2.85e-01 | 4.28e-02 |
| REACTOME MET PROMOTES CELL MOTILITY | 41 | 5.30e-03 | -2.52e-01 | 4.28e-02 |
| REACTOME DEADENYLATION DEPENDENT MRNA DECAY | 56 | 5.31e-03 | 2.15e-01 | 4.28e-02 |
| REACTOME RHOA GTPASE CYCLE | 142 | 5.35e-03 | -1.35e-01 | 4.29e-02 |
| REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION | 59 | 5.39e-03 | 2.09e-01 | 4.30e-02 |
| REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION | 8 | 5.56e-03 | -5.66e-01 | 4.41e-02 |
| REACTOME ASPIRIN ADME | 42 | 5.87e-03 | -2.46e-01 | 4.63e-02 |
| REACTOME COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING | 32 | 5.89e-03 | 2.81e-01 | 4.63e-02 |
| REACTOME TRANSLESION SYNTHESIS BY POLK | 17 | 5.96e-03 | 3.85e-01 | 4.66e-02 |
| REACTOME RHOC GTPASE CYCLE | 71 | 6.02e-03 | -1.88e-01 | 4.68e-02 |
| REACTOME CLEC7A DECTIN 1 SIGNALING | 97 | 6.07e-03 | 1.61e-01 | 4.70e-02 |
| REACTOME CLATHRIN MEDIATED ENDOCYTOSIS | 139 | 6.39e-03 | 1.34e-01 | 4.91e-02 |
| REACTOME NERVOUS SYSTEM DEVELOPMENT | 552 | 6.40e-03 | 6.79e-02 | 4.91e-02 |
| REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE | 11 | 6.60e-03 | -4.73e-01 | 5.04e-02 |
| REACTOME RNA POLYMERASE II PRE TRANSCRIPTION EVENTS | 77 | 6.72e-03 | 1.79e-01 | 5.08e-02 |
| REACTOME REPRODUCTION | 136 | 6.72e-03 | 1.35e-01 | 5.08e-02 |
| REACTOME UNFOLDED PROTEIN RESPONSE UPR | 88 | 6.98e-03 | 1.66e-01 | 5.26e-02 |
| REACTOME HATS ACETYLATE HISTONES | 129 | 7.03e-03 | 1.37e-01 | 5.27e-02 |
| REACTOME TRANSCRIPTIONAL REGULATION BY RUNX3 | 94 | 7.05e-03 | 1.61e-01 | 5.27e-02 |
| REACTOME RESOLUTION OF SISTER CHROMATID COHESION | 120 | 7.33e-03 | 1.42e-01 | 5.45e-02 |
| REACTOME INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION | 21 | 7.38e-03 | -3.38e-01 | 5.46e-02 |
| REACTOME CREATION OF C4 AND C2 ACTIVATORS | 14 | 7.61e-03 | -4.12e-01 | 5.59e-02 |
| REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS | 8 | 7.62e-03 | 5.45e-01 | 5.59e-02 |
| REACTOME ONCOGENE INDUCED SENESCENCE | 35 | 7.86e-03 | 2.60e-01 | 5.73e-02 |
| REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | 28 | 7.94e-03 | 2.90e-01 | 5.77e-02 |
| REACTOME RHO GTPASE EFFECTORS | 305 | 8.05e-03 | 8.82e-02 | 5.82e-02 |
| REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | 46 | 8.46e-03 | 2.24e-01 | 6.10e-02 |
| REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS | 188 | 8.53e-03 | 1.11e-01 | 6.11e-02 |
| REACTOME CARNITINE METABOLISM | 13 | 8.60e-03 | -4.21e-01 | 6.14e-02 |
| REACTOME PCP CE PATHWAY | 91 | 8.71e-03 | 1.59e-01 | 6.19e-02 |
| REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | 11 | 8.76e-03 | 4.56e-01 | 6.20e-02 |
| REACTOME PD 1 SIGNALING | 21 | 9.08e-03 | 3.29e-01 | 6.40e-02 |
| REACTOME MUSCLE CONTRACTION | 197 | 9.12e-03 | -1.08e-01 | 6.40e-02 |
| REACTOME MEIOTIC SYNAPSIS | 73 | 9.22e-03 | 1.76e-01 | 6.43e-02 |
| REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES | 10 | 9.25e-03 | 4.75e-01 | 6.43e-02 |
| REACTOME RHO GTPASES ACTIVATE PKNS | 86 | 9.52e-03 | 1.62e-01 | 6.59e-02 |
| REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | 39 | 9.55e-03 | -2.40e-01 | 6.59e-02 |
| REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | 91 | 1.00e-02 | -1.56e-01 | 6.85e-02 |
| REACTOME ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES | 59 | 1.01e-02 | -1.94e-01 | 6.85e-02 |
| REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR | 79 | 1.01e-02 | 1.67e-01 | 6.85e-02 |
| REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY | 26 | 1.01e-02 | -2.91e-01 | 6.85e-02 |
| REACTOME RNA POLYMERASE III CHAIN ELONGATION | 18 | 1.02e-02 | 3.50e-01 | 6.87e-02 |
| REACTOME FORMATION OF TC NER PRE INCISION COMPLEX | 51 | 1.03e-02 | 2.08e-01 | 6.95e-02 |
| REACTOME OPSINS | 7 | 1.04e-02 | -5.59e-01 | 6.97e-02 |
| REACTOME GENERATION OF SECOND MESSENGER MOLECULES | 30 | 1.06e-02 | 2.70e-01 | 7.05e-02 |
| REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING | 25 | 1.06e-02 | -2.95e-01 | 7.06e-02 |
| REACTOME REGULATION OF PTEN STABILITY AND ACTIVITY | 67 | 1.07e-02 | 1.80e-01 | 7.07e-02 |
| REACTOME MYOCLONIC EPILEPSY OF LAFORA | 9 | 1.13e-02 | 4.88e-01 | 7.46e-02 |
| REACTOME HIV LIFE CYCLE | 145 | 1.17e-02 | 1.21e-01 | 7.68e-02 |
| REACTOME MITOTIC PROPHASE | 134 | 1.17e-02 | 1.26e-01 | 7.68e-02 |
| REACTOME INTERLEUKIN 7 SIGNALING | 31 | 1.25e-02 | 2.59e-01 | 8.15e-02 |
| REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER | 77 | 1.28e-02 | 1.64e-01 | 8.30e-02 |
| REACTOME NEURONAL SYSTEM | 388 | 1.29e-02 | -7.35e-02 | 8.34e-02 |
| REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION | 1356 | 1.30e-02 | 4.02e-02 | 8.37e-02 |
| REACTOME ADRENOCEPTORS | 9 | 1.31e-02 | 4.78e-01 | 8.38e-02 |
| REACTOME LAMININ INTERACTIONS | 28 | 1.33e-02 | -2.70e-01 | 8.45e-02 |
| REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | 38 | 1.33e-02 | 2.32e-01 | 8.45e-02 |
| REACTOME CRISTAE FORMATION | 27 | 1.33e-02 | 2.75e-01 | 8.45e-02 |
| REACTOME RHOB GTPASE CYCLE | 67 | 1.36e-02 | -1.74e-01 | 8.61e-02 |
| REACTOME DNA DOUBLE STRAND BREAK REPAIR | 162 | 1.38e-02 | 1.12e-01 | 8.68e-02 |
| REACTOME TRANSLESION SYNTHESIS BY POLH | 19 | 1.39e-02 | 3.26e-01 | 8.74e-02 |
| REACTOME MITOTIC PROMETAPHASE | 194 | 1.44e-02 | 1.02e-01 | 8.97e-02 |
| REACTOME HEDGEHOG OFF STATE | 111 | 1.46e-02 | 1.34e-01 | 9.05e-02 |
| REACTOME METALLOPROTEASE DUBS | 36 | 1.46e-02 | 2.35e-01 | 9.05e-02 |
| REACTOME PEROXISOMAL PROTEIN IMPORT | 62 | 1.48e-02 | 1.79e-01 | 9.13e-02 |
| REACTOME ION TRANSPORT BY P TYPE ATPASES | 51 | 1.50e-02 | -1.97e-01 | 9.21e-02 |
| REACTOME MATURATION OF SARS COV 1 SPIKE PROTEIN | 5 | 1.51e-02 | 6.28e-01 | 9.25e-02 |
| REACTOME HIV TRANSCRIPTION INITIATION | 43 | 1.56e-02 | 2.13e-01 | 9.47e-02 |
| REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | 99 | 1.56e-02 | 1.41e-01 | 9.47e-02 |
| REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION | 35 | 1.58e-02 | 2.36e-01 | 9.57e-02 |
| REACTOME REGULATION OF SIGNALING BY CBL | 22 | 1.62e-02 | 2.96e-01 | 9.80e-02 |
| REACTOME KEAP1 NFE2L2 PATHWAY | 104 | 1.64e-02 | 1.36e-01 | 9.89e-02 |
| REACTOME MITOCHONDRIAL BIOGENESIS | 87 | 1.65e-02 | 1.49e-01 | 9.89e-02 |
| REACTOME SYNTHESIS OF PA | 38 | 1.67e-02 | -2.24e-01 | 9.99e-02 |
| REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | 123 | 1.71e-02 | -1.25e-01 | 1.02e-01 |
| REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE | 277 | 1.72e-02 | 8.32e-02 | 1.02e-01 |
| REACTOME ACYL CHAIN REMODELLING OF PG | 18 | 1.73e-02 | -3.24e-01 | 1.02e-01 |
| REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS | 66 | 1.73e-02 | -1.69e-01 | 1.02e-01 |
| REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX | 85 | 1.80e-02 | 1.48e-01 | 1.05e-01 |
| REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION | 62 | 1.81e-02 | 1.73e-01 | 1.06e-01 |
| REACTOME CDC42 GTPASE CYCLE | 144 | 1.82e-02 | -1.14e-01 | 1.06e-01 |
| REACTOME INTESTINAL ABSORPTION | 5 | 1.82e-02 | -6.10e-01 | 1.06e-01 |
| REACTOME NRAGE SIGNALS DEATH THROUGH JNK | 53 | 1.88e-02 | -1.87e-01 | 1.09e-01 |
| REACTOME EXTENSION OF TELOMERES | 49 | 1.89e-02 | 1.94e-01 | 1.09e-01 |
| REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B | 24 | 1.89e-02 | 2.77e-01 | 1.09e-01 |
| REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | 122 | 1.91e-02 | 1.23e-01 | 1.09e-01 |
| REACTOME INTERFERON ALPHA BETA SIGNALING | 70 | 1.92e-02 | 1.62e-01 | 1.09e-01 |
| REACTOME SIGNALING BY HEDGEHOG | 148 | 1.93e-02 | 1.11e-01 | 1.09e-01 |
| REACTOME TRANSCRIPTION OF THE HIV GENOME | 66 | 1.93e-02 | 1.66e-01 | 1.09e-01 |
| REACTOME RMTS METHYLATE HISTONE ARGININES | 72 | 1.94e-02 | 1.59e-01 | 1.09e-01 |
| REACTOME LYSINE CATABOLISM | 12 | 1.95e-02 | 3.89e-01 | 1.10e-01 |
| REACTOME MITOTIC SPINDLE CHECKPOINT | 109 | 1.96e-02 | 1.29e-01 | 1.10e-01 |
| REACTOME DUAL INCISION IN TC NER | 63 | 1.97e-02 | 1.70e-01 | 1.10e-01 |
| REACTOME INTEGRIN CELL SURFACE INTERACTIONS | 83 | 2.00e-02 | -1.48e-01 | 1.11e-01 |
| REACTOME SCAVENGING OF HEME FROM PLASMA | 13 | 2.02e-02 | -3.72e-01 | 1.12e-01 |
| REACTOME PREVENTION OF PHAGOSOMAL LYSOSOMAL FUSION | 9 | 2.04e-02 | 4.46e-01 | 1.13e-01 |
| REACTOME REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE | 81 | 2.05e-02 | 1.49e-01 | 1.13e-01 |
| REACTOME RNA POLYMERASE III TRANSCRIPTION TERMINATION | 23 | 2.07e-02 | 2.79e-01 | 1.14e-01 |
| REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | 28 | 2.10e-02 | 2.52e-01 | 1.15e-01 |
| REACTOME ACYL CHAIN REMODELLING OF PS | 22 | 2.12e-02 | -2.84e-01 | 1.16e-01 |
| REACTOME PROTEIN FOLDING | 96 | 2.13e-02 | 1.36e-01 | 1.16e-01 |
| REACTOME TELOMERE C STRAND SYNTHESIS INITIATION | 12 | 2.18e-02 | 3.82e-01 | 1.18e-01 |
| REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | 37 | 2.20e-02 | 2.18e-01 | 1.19e-01 |
| REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER | 28 | 2.23e-02 | 2.50e-01 | 1.20e-01 |
| REACTOME TRNA PROCESSING | 105 | 2.23e-02 | 1.29e-01 | 1.20e-01 |
| REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | 18 | 2.26e-02 | -3.10e-01 | 1.21e-01 |
| REACTOME SYNDECAN INTERACTIONS | 26 | 2.30e-02 | -2.58e-01 | 1.22e-01 |
| REACTOME COMPLEX I BIOGENESIS | 49 | 2.34e-02 | 1.87e-01 | 1.24e-01 |
| REACTOME INTERLEUKIN 12 SIGNALING | 43 | 2.40e-02 | 1.99e-01 | 1.27e-01 |
| REACTOME REGULATION OF GENE EXPRESSION IN ENDOCRINE COMMITTED NEUROG3 PROGENITOR CELLS | 5 | 2.41e-02 | 5.82e-01 | 1.27e-01 |
| REACTOME INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL | 14 | 2.42e-02 | 3.48e-01 | 1.28e-01 |
| REACTOME REGULATION OF TP53 ACTIVITY THROUGH METHYLATION | 19 | 2.50e-02 | 2.97e-01 | 1.31e-01 |
| REACTOME RNA POLYMERASE III TRANSCRIPTION | 41 | 2.55e-02 | 2.02e-01 | 1.33e-01 |
| REACTOME INTERLEUKIN 36 PATHWAY | 7 | 2.60e-02 | -4.86e-01 | 1.36e-01 |
| REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | 296 | 2.63e-02 | 7.51e-02 | 1.37e-01 |
| REACTOME DNA DAMAGE RECOGNITION IN GG NER | 36 | 2.67e-02 | 2.13e-01 | 1.38e-01 |
| REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ | 6 | 2.67e-02 | -5.22e-01 | 1.38e-01 |
| REACTOME NUCLEOTIDE EXCISION REPAIR | 107 | 2.73e-02 | 1.24e-01 | 1.40e-01 |
| REACTOME MODULATION BY MTB OF HOST IMMUNE SYSTEM | 6 | 2.74e-02 | 5.20e-01 | 1.41e-01 |
| REACTOME INTERLEUKIN 27 SIGNALING | 11 | 2.75e-02 | 3.84e-01 | 1.41e-01 |
| REACTOME PHOSPHOLIPID METABOLISM | 201 | 2.76e-02 | -9.01e-02 | 1.41e-01 |
| REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES | 11 | 2.78e-02 | 3.83e-01 | 1.41e-01 |
| REACTOME DUAL INCISION IN GG NER | 39 | 2.82e-02 | 2.03e-01 | 1.43e-01 |
| REACTOME TRNA PROCESSING IN THE NUCLEUS | 58 | 2.84e-02 | 1.66e-01 | 1.43e-01 |
| REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION | 45 | 2.85e-02 | 1.89e-01 | 1.43e-01 |
| REACTOME FLT3 SIGNALING THROUGH SRC FAMILY KINASES | 6 | 2.87e-02 | 5.16e-01 | 1.43e-01 |
| REACTOME GLUCURONIDATION | 23 | 2.87e-02 | -2.63e-01 | 1.43e-01 |
| REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON | 17 | 2.87e-02 | 3.06e-01 | 1.43e-01 |
| REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE | 5 | 2.90e-02 | -5.64e-01 | 1.44e-01 |
| REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA | 11 | 2.99e-02 | -3.78e-01 | 1.48e-01 |
| REACTOME CYCLIN D ASSOCIATED EVENTS IN G1 | 46 | 3.04e-02 | 1.84e-01 | 1.51e-01 |
| REACTOME FLT3 SIGNALING | 38 | 3.06e-02 | 2.03e-01 | 1.51e-01 |
| REACTOME GLUTATHIONE CONJUGATION | 33 | 3.08e-02 | 2.17e-01 | 1.52e-01 |
| REACTOME RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR | 19 | 3.10e-02 | -2.86e-01 | 1.52e-01 |
| REACTOME RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY | 14 | 3.14e-02 | 3.32e-01 | 1.53e-01 |
| REACTOME SIGNALING BY CSF3 G CSF | 30 | 3.20e-02 | 2.26e-01 | 1.56e-01 |
| REACTOME SMOOTH MUSCLE CONTRACTION | 43 | 3.20e-02 | -1.89e-01 | 1.56e-01 |
| REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION | 26 | 3.22e-02 | 2.43e-01 | 1.56e-01 |
| REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES | 27 | 3.30e-02 | 2.37e-01 | 1.59e-01 |
| REACTOME ORGANIC ANION TRANSPORT | 5 | 3.35e-02 | -5.49e-01 | 1.61e-01 |
| REACTOME PHENYLALANINE AND TYROSINE METABOLISM | 11 | 3.44e-02 | -3.68e-01 | 1.65e-01 |
| REACTOME TELOMERE C STRAND LAGGING STRAND SYNTHESIS | 33 | 3.47e-02 | 2.12e-01 | 1.66e-01 |
| REACTOME PI3K EVENTS IN ERBB4 SIGNALING | 10 | 3.50e-02 | 3.85e-01 | 1.67e-01 |
| REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | 101 | 3.58e-02 | -1.21e-01 | 1.70e-01 |
| REACTOME FGFR2 ALTERNATIVE SPLICING | 27 | 3.60e-02 | 2.33e-01 | 1.71e-01 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH CDK5 | 6 | 3.60e-02 | 4.94e-01 | 1.71e-01 |
| REACTOME CD28 DEPENDENT VAV1 PATHWAY | 11 | 3.63e-02 | 3.65e-01 | 1.71e-01 |
| REACTOME SIGNALING BY ERBB4 | 57 | 3.68e-02 | 1.60e-01 | 1.73e-01 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH PI3K | 7 | 3.68e-02 | 4.56e-01 | 1.73e-01 |
| REACTOME FREE FATTY ACIDS REGULATE INSULIN SECRETION | 10 | 3.71e-02 | -3.81e-01 | 1.74e-01 |
| REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA | 28 | 3.73e-02 | 2.27e-01 | 1.74e-01 |
| REACTOME MITOPHAGY | 28 | 3.78e-02 | 2.27e-01 | 1.76e-01 |
| REACTOME DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA | 77 | 3.81e-02 | 1.37e-01 | 1.76e-01 |
| REACTOME RAC1 GTPASE CYCLE | 172 | 3.81e-02 | -9.16e-02 | 1.76e-01 |
| REACTOME GENE SILENCING BY RNA | 133 | 3.82e-02 | 1.04e-01 | 1.76e-01 |
| REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | 26 | 3.87e-02 | 2.34e-01 | 1.78e-01 |
| REACTOME SEROTONIN RECEPTORS | 11 | 3.89e-02 | 3.60e-01 | 1.78e-01 |
| REACTOME INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING | 103 | 3.90e-02 | 1.18e-01 | 1.78e-01 |
| REACTOME PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING | 11 | 3.92e-02 | -3.59e-01 | 1.79e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | 81 | 3.93e-02 | 1.32e-01 | 1.79e-01 |
| REACTOME HDR THROUGH HOMOLOGOUS RECOMBINATION HRR | 66 | 3.95e-02 | 1.47e-01 | 1.79e-01 |
| REACTOME MRNA SPLICING MINOR PATHWAY | 49 | 4.02e-02 | 1.69e-01 | 1.82e-01 |
| REACTOME HS GAG BIOSYNTHESIS | 28 | 4.02e-02 | -2.24e-01 | 1.82e-01 |
| REACTOME METABOLISM OF LIPIDS | 709 | 4.10e-02 | -4.50e-02 | 1.84e-01 |
| REACTOME TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER | 76 | 4.11e-02 | 1.36e-01 | 1.84e-01 |
| REACTOME AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS | 9 | 4.13e-02 | -3.93e-01 | 1.85e-01 |
| REACTOME TYPE I HEMIDESMOSOME ASSEMBLY | 11 | 4.15e-02 | -3.55e-01 | 1.85e-01 |
| REACTOME HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR IN THE PRESENCE OF LIGAND | 55 | 4.19e-02 | 1.59e-01 | 1.87e-01 |
| REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | 31 | 4.26e-02 | 2.10e-01 | 1.89e-01 |
| REACTOME DIGESTION OF DIETARY LIPID | 7 | 4.27e-02 | -4.42e-01 | 1.89e-01 |
| REACTOME OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS | 8 | 4.30e-02 | -4.13e-01 | 1.89e-01 |
| REACTOME ACYL CHAIN REMODELLING OF PE | 29 | 4.31e-02 | -2.17e-01 | 1.89e-01 |
| REACTOME ACTIVATION OF C3 AND C5 | 6 | 4.31e-02 | -4.77e-01 | 1.89e-01 |
| REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX | 57 | 4.43e-02 | 1.54e-01 | 1.93e-01 |
| REACTOME PYROPTOSIS | 27 | 4.43e-02 | 2.24e-01 | 1.93e-01 |
| REACTOME IRON UPTAKE AND TRANSPORT | 56 | 4.46e-02 | 1.55e-01 | 1.94e-01 |
| REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | 30 | 4.47e-02 | -2.12e-01 | 1.94e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES | 61 | 4.48e-02 | 1.49e-01 | 1.94e-01 |
| REACTOME SIGNALING BY NTRKS | 132 | 4.52e-02 | 1.01e-01 | 1.95e-01 |
| REACTOME KSRP KHSRP BINDS AND DESTABILIZES MRNA | 17 | 4.55e-02 | 2.80e-01 | 1.95e-01 |
| REACTOME ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN | 13 | 4.55e-02 | -3.20e-01 | 1.95e-01 |
| REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | 22 | 4.58e-02 | 2.46e-01 | 1.96e-01 |
| REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS | 6 | 4.62e-02 | 4.70e-01 | 1.97e-01 |
| REACTOME RHOQ GTPASE CYCLE | 57 | 4.62e-02 | -1.53e-01 | 1.97e-01 |
| REACTOME RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX | 29 | 4.64e-02 | 2.14e-01 | 1.98e-01 |
| REACTOME PI3K EVENTS IN ERBB2 SIGNALING | 16 | 4.66e-02 | 2.87e-01 | 1.98e-01 |
| REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | 122 | 4.70e-02 | -1.04e-01 | 1.99e-01 |
| REACTOME SIGNALING BY NOTCH2 | 32 | 4.73e-02 | 2.03e-01 | 1.99e-01 |
| REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | 16 | 4.73e-02 | 2.86e-01 | 1.99e-01 |
| REACTOME REGULATION OF BACH1 ACTIVITY | 11 | 4.74e-02 | 3.45e-01 | 1.99e-01 |
| REACTOME TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA | 17 | 4.75e-02 | 2.78e-01 | 1.99e-01 |
| REACTOME ELASTIC FIBRE FORMATION | 44 | 4.79e-02 | -1.72e-01 | 2.00e-01 |
| REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | 15 | 4.81e-02 | -2.95e-01 | 2.01e-01 |
| REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER | 81 | 4.85e-02 | 1.27e-01 | 2.02e-01 |
| REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION | 90 | 4.92e-02 | 1.20e-01 | 2.04e-01 |
| REACTOME PTEN REGULATION | 135 | 4.95e-02 | 9.79e-02 | 2.05e-01 |
| REACTOME JOSEPHIN DOMAIN DUBS | 11 | 4.96e-02 | 3.42e-01 | 2.05e-01 |
| REACTOME STAT5 ACTIVATION | 7 | 5.03e-02 | 4.27e-01 | 2.07e-01 |
| REACTOME DEFECTIVE LFNG CAUSES SCDO3 | 5 | 5.08e-02 | -5.04e-01 | 2.09e-01 |
| REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX | 13 | 5.09e-02 | 3.13e-01 | 2.09e-01 |
| REACTOME FCERI MEDIATED CA 2 MOBILIZATION | 30 | 5.20e-02 | 2.05e-01 | 2.12e-01 |
| REACTOME CHYLOMICRON REMODELING | 10 | 5.23e-02 | -3.54e-01 | 2.13e-01 |
| REACTOME DIGESTION OF DIETARY CARBOHYDRATE | 6 | 5.23e-02 | -4.57e-01 | 2.13e-01 |
| REACTOME FORMATION OF INCISION COMPLEX IN GG NER | 40 | 5.24e-02 | 1.77e-01 | 2.13e-01 |
| REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS | 28 | 5.26e-02 | 2.12e-01 | 2.13e-01 |
| REACTOME HDR THROUGH SINGLE STRAND ANNEALING SSA | 37 | 5.34e-02 | 1.83e-01 | 2.16e-01 |
| REACTOME RAB GERANYLGERANYLATION | 57 | 5.40e-02 | 1.48e-01 | 2.17e-01 |
| REACTOME TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7 | 12 | 5.52e-02 | 3.20e-01 | 2.22e-01 |
| REACTOME CELL JUNCTION ORGANIZATION | 89 | 5.54e-02 | -1.18e-01 | 2.22e-01 |
| REACTOME VLDLR INTERNALISATION AND DEGRADATION | 16 | 5.62e-02 | 2.76e-01 | 2.24e-01 |
| REACTOME POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE | 25 | 5.63e-02 | 2.21e-01 | 2.24e-01 |
| REACTOME TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS | 82 | 5.63e-02 | -1.22e-01 | 2.24e-01 |
| REACTOME TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT | 18 | 5.66e-02 | 2.60e-01 | 2.24e-01 |
| REACTOME CELL CELL COMMUNICATION | 126 | 5.73e-02 | -9.81e-02 | 2.27e-01 |
| REACTOME PRE NOTCH PROCESSING IN GOLGI | 18 | 5.84e-02 | -2.58e-01 | 2.30e-01 |
| REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM | 78 | 5.84e-02 | 1.24e-01 | 2.30e-01 |
| REACTOME REGULATION OF PTEN LOCALIZATION | 8 | 5.87e-02 | 3.86e-01 | 2.30e-01 |
| REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | 15 | 5.88e-02 | 2.82e-01 | 2.30e-01 |
| REACTOME INTERLEUKIN 10 SIGNALING | 43 | 5.90e-02 | 1.66e-01 | 2.31e-01 |
| REACTOME DNA DOUBLE STRAND BREAK RESPONSE | 74 | 5.92e-02 | 1.27e-01 | 2.31e-01 |
| REACTOME INTEGRATION OF ENERGY METABOLISM | 105 | 5.97e-02 | -1.06e-01 | 2.32e-01 |
| REACTOME INTERFERON SIGNALING | 193 | 6.01e-02 | 7.85e-02 | 2.33e-01 |
| REACTOME CHOLESTEROL BIOSYNTHESIS | 25 | 6.06e-02 | -2.17e-01 | 2.35e-01 |
| REACTOME CELLULAR RESPONSE TO HEAT STRESS | 99 | 6.08e-02 | 1.09e-01 | 2.35e-01 |
| REACTOME GLYCOGEN SYNTHESIS | 13 | 6.10e-02 | 3.00e-01 | 2.35e-01 |
| REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES | 18 | 6.14e-02 | -2.55e-01 | 2.36e-01 |
| REACTOME REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION | 84 | 6.15e-02 | 1.18e-01 | 2.36e-01 |
| REACTOME RHO GTPASES ACTIVATE FORMINS | 136 | 6.19e-02 | 9.27e-02 | 2.37e-01 |
| REACTOME GP1B IX V ACTIVATION SIGNALLING | 11 | 6.20e-02 | -3.25e-01 | 2.37e-01 |
| REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS | 299 | 6.22e-02 | 6.27e-02 | 2.37e-01 |
| REACTOME SIGNAL AMPLIFICATION | 33 | 6.29e-02 | 1.87e-01 | 2.39e-01 |
| REACTOME MRNA CAPPING | 28 | 6.31e-02 | 2.03e-01 | 2.39e-01 |
| REACTOME GLYCOGEN STORAGE DISEASES | 15 | 6.33e-02 | 2.77e-01 | 2.39e-01 |
| REACTOME REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS | 14 | 6.34e-02 | -2.87e-01 | 2.39e-01 |
| REACTOME CHAPERONE MEDIATED AUTOPHAGY | 20 | 6.37e-02 | 2.40e-01 | 2.40e-01 |
| REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A | 26 | 6.38e-02 | 2.10e-01 | 2.40e-01 |
| REACTOME SNRNP ASSEMBLY | 53 | 6.40e-02 | 1.47e-01 | 2.40e-01 |
| REACTOME INTERLEUKIN 1 FAMILY SIGNALING | 146 | 6.48e-02 | 8.85e-02 | 2.42e-01 |
| REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP | 41 | 6.49e-02 | -1.67e-01 | 2.42e-01 |
| REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS | 63 | 6.52e-02 | -1.34e-01 | 2.43e-01 |
| REACTOME TRANS GOLGI NETWORK VESICLE BUDDING | 67 | 6.58e-02 | 1.30e-01 | 2.44e-01 |
| REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL | 58 | 6.60e-02 | 1.40e-01 | 2.44e-01 |
| REACTOME CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER | 25 | 6.60e-02 | -2.12e-01 | 2.44e-01 |
| REACTOME HORMONE LIGAND BINDING RECEPTORS | 12 | 6.78e-02 | -3.05e-01 | 2.49e-01 |
| REACTOME SIGNALING BY ALK IN CANCER | 53 | 6.78e-02 | 1.45e-01 | 2.49e-01 |
| REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES | 37 | 6.79e-02 | -1.73e-01 | 2.49e-01 |
| REACTOME DISEASES OF DNA REPAIR | 51 | 6.81e-02 | 1.48e-01 | 2.50e-01 |
| REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION | 23 | 6.83e-02 | 2.20e-01 | 2.50e-01 |
| REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX | 15 | 6.85e-02 | 2.72e-01 | 2.50e-01 |
| REACTOME HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE | 43 | 6.86e-02 | 1.61e-01 | 2.50e-01 |
| REACTOME EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION | 27 | 6.91e-02 | -2.02e-01 | 2.51e-01 |
| REACTOME ORGANIC ANION TRANSPORTERS | 10 | 6.94e-02 | 3.32e-01 | 2.52e-01 |
| REACTOME SIGNALING BY BMP | 27 | 7.02e-02 | -2.01e-01 | 2.54e-01 |
| REACTOME DEFECTIVE EXT2 CAUSES EXOSTOSES 2 | 12 | 7.04e-02 | -3.02e-01 | 2.54e-01 |
| REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | 129 | 7.08e-02 | 9.21e-02 | 2.55e-01 |
| REACTOME GERM LAYER FORMATION AT GASTRULATION | 17 | 7.21e-02 | 2.52e-01 | 2.58e-01 |
| REACTOME P75NTR REGULATES AXONOGENESIS | 9 | 7.21e-02 | -3.46e-01 | 2.58e-01 |
| REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | 80 | 7.22e-02 | 1.16e-01 | 2.58e-01 |
| REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION | 10 | 7.23e-02 | 3.28e-01 | 2.58e-01 |
| REACTOME DEFECTIVE CHST14 CAUSES EDS MUSCULOCONTRACTURAL TYPE | 7 | 7.26e-02 | 3.92e-01 | 2.58e-01 |
| REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER | 18 | 7.26e-02 | 2.44e-01 | 2.58e-01 |
| REACTOME G0 AND EARLY G1 | 27 | 7.27e-02 | 2.00e-01 | 2.58e-01 |
| REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS | 8 | 7.31e-02 | -3.66e-01 | 2.59e-01 |
| REACTOME SIGNALING BY FGFR2 | 72 | 7.44e-02 | 1.22e-01 | 2.63e-01 |
| REACTOME NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 11 | 7.48e-02 | 3.10e-01 | 2.63e-01 |
| REACTOME NEGATIVE REGULATION OF MET ACTIVITY | 20 | 7.50e-02 | 2.30e-01 | 2.64e-01 |
| REACTOME INFECTION WITH MYCOBACTERIUM TUBERCULOSIS | 25 | 7.56e-02 | 2.05e-01 | 2.65e-01 |
| REACTOME HYDROLYSIS OF LPC | 9 | 7.57e-02 | -3.42e-01 | 2.65e-01 |
| REACTOME HSF1 ACTIVATION | 29 | 7.61e-02 | 1.90e-01 | 2.65e-01 |
| REACTOME PHENYLALANINE METABOLISM | 6 | 7.61e-02 | -4.18e-01 | 2.65e-01 |
| REACTOME DERMATAN SULFATE BIOSYNTHESIS | 10 | 7.68e-02 | 3.23e-01 | 2.67e-01 |
| REACTOME RAF ACTIVATION | 33 | 7.70e-02 | -1.78e-01 | 2.67e-01 |
| REACTOME SARS COV 2 ACTIVATES MODULATES INNATE AND ADAPTIVE IMMUNE RESPONSES | 118 | 7.77e-02 | 9.40e-02 | 2.69e-01 |
| REACTOME TOLL LIKE RECEPTOR CASCADES | 158 | 7.79e-02 | 8.13e-02 | 2.69e-01 |
| REACTOME ACYL CHAIN REMODELLING OF PI | 17 | 7.87e-02 | -2.46e-01 | 2.72e-01 |
| REACTOME VASOPRESSIN LIKE RECEPTORS | 5 | 7.92e-02 | 4.53e-01 | 2.73e-01 |
| REACTOME BETA CATENIN INDEPENDENT WNT SIGNALING | 145 | 8.00e-02 | 8.42e-02 | 2.75e-01 |
| REACTOME CHROMATIN MODIFYING ENZYMES | 252 | 8.01e-02 | 6.40e-02 | 2.75e-01 |
| REACTOME CONDENSATION OF PROMETAPHASE CHROMOSOMES | 11 | 8.05e-02 | 3.04e-01 | 2.75e-01 |
| REACTOME METABOLISM OF FAT SOLUBLE VITAMINS | 46 | 8.08e-02 | -1.49e-01 | 2.76e-01 |
| REACTOME REGULATION OF IFNA IFNB SIGNALING | 23 | 8.09e-02 | 2.10e-01 | 2.76e-01 |
| REACTOME RORA ACTIVATES GENE EXPRESSION | 17 | 8.20e-02 | -2.44e-01 | 2.79e-01 |
| REACTOME RESPONSE OF MTB TO PHAGOCYTOSIS | 22 | 8.21e-02 | 2.14e-01 | 2.79e-01 |
| REACTOME SENSORY PERCEPTION OF SALTY TASTE | 6 | 8.25e-02 | -4.09e-01 | 2.79e-01 |
| REACTOME FERTILIZATION | 26 | 8.37e-02 | -1.96e-01 | 2.83e-01 |
| REACTOME SIGNALING BY NODAL | 20 | 8.40e-02 | -2.23e-01 | 2.83e-01 |
| REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION | 9 | 8.43e-02 | 3.32e-01 | 2.83e-01 |
| REACTOME REGULATION OF TP53 ACTIVITY | 156 | 8.43e-02 | 8.01e-02 | 2.83e-01 |
| REACTOME CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA | 63 | 8.50e-02 | 1.25e-01 | 2.85e-01 |
| REACTOME TRANSPORT OF NUCLEOTIDE SUGARS | 8 | 8.68e-02 | -3.50e-01 | 2.90e-01 |
| REACTOME DOWNREGULATION OF ERBB2 SIGNALING | 29 | 8.70e-02 | 1.84e-01 | 2.90e-01 |
| REACTOME CITRIC ACID CYCLE TCA CYCLE | 21 | 8.80e-02 | 2.15e-01 | 2.93e-01 |
| REACTOME REGULATION OF FZD BY UBIQUITINATION | 21 | 8.81e-02 | 2.15e-01 | 2.93e-01 |
| REACTOME POLO LIKE KINASE MEDIATED EVENTS | 16 | 8.86e-02 | 2.46e-01 | 2.94e-01 |
| REACTOME MUSCARINIC ACETYLCHOLINE RECEPTORS | 5 | 8.90e-02 | -4.39e-01 | 2.95e-01 |
| REACTOME TRP CHANNELS | 27 | 8.95e-02 | -1.89e-01 | 2.95e-01 |
| REACTOME ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE | 9 | 8.96e-02 | -3.27e-01 | 2.95e-01 |
| REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS | 42 | 9.01e-02 | -1.51e-01 | 2.96e-01 |
| REACTOME TRNA AMINOACYLATION | 40 | 9.02e-02 | 1.55e-01 | 2.96e-01 |
| REACTOME SUPPRESSION OF PHAGOSOMAL MATURATION | 13 | 9.07e-02 | 2.71e-01 | 2.97e-01 |
| REACTOME DEFECTIVE F9 ACTIVATION | 5 | 9.10e-02 | -4.36e-01 | 2.98e-01 |
| REACTOME GASTRULATION | 49 | 9.13e-02 | 1.39e-01 | 2.98e-01 |
| REACTOME DOWNREGULATION OF ERBB4 SIGNALING | 9 | 9.19e-02 | 3.24e-01 | 2.99e-01 |
| REACTOME MEMBRANE TRAFFICKING | 603 | 9.22e-02 | 4.01e-02 | 3.00e-01 |
| REACTOME COSTIMULATION BY THE CD28 FAMILY | 64 | 9.36e-02 | 1.21e-01 | 3.04e-01 |
| REACTOME VXPX CARGO TARGETING TO CILIUM | 20 | 9.37e-02 | -2.16e-01 | 3.04e-01 |
| REACTOME FOXO MEDIATED TRANSCRIPTION | 65 | 9.51e-02 | 1.20e-01 | 3.07e-01 |
| REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES | 12 | 9.55e-02 | 2.78e-01 | 3.07e-01 |
| REACTOME EGFR DOWNREGULATION | 30 | 9.55e-02 | 1.76e-01 | 3.07e-01 |
| REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS | 5 | 9.57e-02 | -4.30e-01 | 3.07e-01 |
| REACTOME ASSEMBLY OF THE HIV VIRION | 16 | 9.57e-02 | 2.41e-01 | 3.07e-01 |
| REACTOME SUMOYLATION OF DNA METHYLATION PROTEINS | 16 | 9.62e-02 | -2.40e-01 | 3.08e-01 |
| REACTOME SIGNALING BY EGFR IN CANCER | 25 | 9.64e-02 | 1.92e-01 | 3.08e-01 |
| REACTOME TRIGLYCERIDE CATABOLISM | 23 | 9.85e-02 | 1.99e-01 | 3.14e-01 |
| REACTOME P75NTR SIGNALS VIA NF KB | 15 | 9.88e-02 | 2.46e-01 | 3.14e-01 |
| REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | 111 | 9.89e-02 | 9.07e-02 | 3.14e-01 |
| REACTOME ARACHIDONATE PRODUCTION FROM DAG | 5 | 1.00e-01 | -4.25e-01 | 3.17e-01 |
| REACTOME IRAK1 RECRUITS IKK COMPLEX | 12 | 1.00e-01 | 2.74e-01 | 3.17e-01 |
| REACTOME REGULATION OF SIGNALING BY NODAL | 9 | 1.01e-01 | -3.16e-01 | 3.18e-01 |
| REACTOME RSK ACTIVATION | 5 | 1.01e-01 | -4.23e-01 | 3.18e-01 |
| REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS | 53 | 1.01e-01 | 1.30e-01 | 3.18e-01 |
| REACTOME CD209 DC SIGN SIGNALING | 20 | 1.01e-01 | -2.12e-01 | 3.18e-01 |
| REACTOME DISEASES OF GLYCOSYLATION | 137 | 1.02e-01 | -8.09e-02 | 3.20e-01 |
| REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | 38 | 1.03e-01 | -1.53e-01 | 3.21e-01 |
| REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS | 16 | 1.03e-01 | 2.36e-01 | 3.21e-01 |
| REACTOME GAB1 SIGNALOSOME | 17 | 1.03e-01 | 2.28e-01 | 3.21e-01 |
| REACTOME MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS | 13 | 1.04e-01 | 2.61e-01 | 3.21e-01 |
| REACTOME LATE ENDOSOMAL MICROAUTOPHAGY | 33 | 1.04e-01 | 1.64e-01 | 3.21e-01 |
| REACTOME CAMK IV MEDIATED PHOSPHORYLATION OF CREB | 10 | 1.04e-01 | -2.97e-01 | 3.23e-01 |
| REACTOME RA BIOSYNTHESIS PATHWAY | 22 | 1.04e-01 | 2.00e-01 | 3.23e-01 |
| REACTOME TOLL LIKE RECEPTOR 9 TLR9 CASCADE | 100 | 1.05e-01 | 9.37e-02 | 3.25e-01 |
| REACTOME DEFECTIVE CHSY1 CAUSES TPBS | 7 | 1.06e-01 | 3.53e-01 | 3.26e-01 |
| REACTOME MYD88 INDEPENDENT TLR4 CASCADE | 103 | 1.06e-01 | 9.22e-02 | 3.26e-01 |
| REACTOME TELOMERE EXTENSION BY TELOMERASE | 22 | 1.07e-01 | 1.99e-01 | 3.28e-01 |
| REACTOME NONHOMOLOGOUS END JOINING NHEJ | 64 | 1.08e-01 | 1.16e-01 | 3.29e-01 |
| REACTOME VEGFR2 MEDIATED CELL PROLIFERATION | 19 | 1.08e-01 | -2.13e-01 | 3.29e-01 |
| REACTOME AUTOPHAGY | 144 | 1.08e-01 | 7.76e-02 | 3.29e-01 |
| REACTOME RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES | 16 | 1.08e-01 | -2.32e-01 | 3.30e-01 |
| REACTOME G ALPHA 12 13 SIGNALLING EVENTS | 74 | 1.09e-01 | -1.08e-01 | 3.30e-01 |
| REACTOME RETINOID CYCLE DISEASE EVENTS | 11 | 1.10e-01 | -2.78e-01 | 3.34e-01 |
| REACTOME DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS | 14 | 1.10e-01 | -2.47e-01 | 3.34e-01 |
| REACTOME GDP FUCOSE BIOSYNTHESIS | 6 | 1.11e-01 | -3.76e-01 | 3.36e-01 |
| REACTOME PROCESSING OF INTRONLESS PRE MRNAS | 19 | 1.12e-01 | 2.11e-01 | 3.36e-01 |
| REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | 11 | 1.12e-01 | 2.77e-01 | 3.36e-01 |
| REACTOME INACTIVATION OF CSF3 G CSF SIGNALING | 25 | 1.12e-01 | 1.84e-01 | 3.37e-01 |
| REACTOME ACTIVATION OF CASPASES THROUGH APOPTOSOME MEDIATED CLEAVAGE | 5 | 1.13e-01 | 4.10e-01 | 3.38e-01 |
| REACTOME DRUG MEDIATED INHIBITION OF CDK4 CDK6 ACTIVITY | 5 | 1.14e-01 | 4.08e-01 | 3.41e-01 |
| REACTOME SUMOYLATION | 179 | 1.14e-01 | 6.85e-02 | 3.41e-01 |
| REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | 13 | 1.14e-01 | -2.53e-01 | 3.41e-01 |
| REACTOME RELAXIN RECEPTORS | 8 | 1.17e-01 | 3.20e-01 | 3.47e-01 |
| REACTOME ION HOMEOSTASIS | 52 | 1.19e-01 | -1.25e-01 | 3.53e-01 |
| REACTOME BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA | 17 | 1.19e-01 | 2.18e-01 | 3.53e-01 |
| REACTOME REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS | 11 | 1.20e-01 | -2.71e-01 | 3.56e-01 |
| REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION | 29 | 1.21e-01 | -1.66e-01 | 3.58e-01 |
| REACTOME TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX | 10 | 1.21e-01 | 2.83e-01 | 3.59e-01 |
| REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX | 9 | 1.22e-01 | 2.98e-01 | 3.59e-01 |
| REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | 11 | 1.22e-01 | 2.69e-01 | 3.59e-01 |
| REACTOME CELLULAR HEXOSE TRANSPORT | 21 | 1.22e-01 | -1.95e-01 | 3.59e-01 |
| REACTOME COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING | 38 | 1.23e-01 | 1.45e-01 | 3.59e-01 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS | 7 | 1.23e-01 | -3.37e-01 | 3.59e-01 |
| REACTOME DISEASES ASSOCIATED WITH SURFACTANT METABOLISM | 9 | 1.23e-01 | -2.97e-01 | 3.60e-01 |
| REACTOME MET ACTIVATES RAP1 AND RAC1 | 11 | 1.24e-01 | 2.68e-01 | 3.61e-01 |
| REACTOME BICARBONATE TRANSPORTERS | 10 | 1.24e-01 | -2.81e-01 | 3.61e-01 |
| REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | 26 | 1.24e-01 | 1.74e-01 | 3.61e-01 |
| REACTOME DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A | 5 | 1.25e-01 | -3.96e-01 | 3.62e-01 |
| REACTOME COMPLEMENT CASCADE | 54 | 1.27e-01 | -1.20e-01 | 3.67e-01 |
| REACTOME STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS | 10 | 1.27e-01 | 2.79e-01 | 3.68e-01 |
| REACTOME STRIATED MUSCLE CONTRACTION | 35 | 1.28e-01 | -1.49e-01 | 3.68e-01 |
| REACTOME CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT | 19 | 1.28e-01 | 2.02e-01 | 3.68e-01 |
| REACTOME SIGNALING BY CSF1 M CSF IN MYELOID CELLS | 30 | 1.29e-01 | 1.60e-01 | 3.71e-01 |
| REACTOME PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR | 21 | 1.31e-01 | 1.91e-01 | 3.74e-01 |
| REACTOME PROTEIN METHYLATION | 17 | 1.31e-01 | 2.12e-01 | 3.74e-01 |
| REACTOME TRAFFICKING OF AMPA RECEPTORS | 29 | 1.31e-01 | -1.62e-01 | 3.75e-01 |
| REACTOME FANCONI ANEMIA PATHWAY | 35 | 1.31e-01 | 1.47e-01 | 3.75e-01 |
| REACTOME IRAK4 DEFICIENCY TLR2 4 | 17 | 1.32e-01 | 2.11e-01 | 3.76e-01 |
| REACTOME G2 M DNA REPLICATION CHECKPOINT | 5 | 1.33e-01 | 3.88e-01 | 3.78e-01 |
| REACTOME INOSITOL PHOSPHATE METABOLISM | 45 | 1.34e-01 | -1.29e-01 | 3.81e-01 |
| REACTOME NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION | 193 | 1.34e-01 | -6.25e-02 | 3.81e-01 |
| REACTOME METABOLISM OF COFACTORS | 19 | 1.35e-01 | 1.98e-01 | 3.82e-01 |
| REACTOME ALPHA OXIDATION OF PHYTANATE | 6 | 1.35e-01 | 3.52e-01 | 3.82e-01 |
| REACTOME G1 S SPECIFIC TRANSCRIPTION | 28 | 1.35e-01 | 1.63e-01 | 3.82e-01 |
| REACTOME REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS | 15 | 1.36e-01 | 2.23e-01 | 3.82e-01 |
| REACTOME TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY | 16 | 1.36e-01 | 2.15e-01 | 3.82e-01 |
| REACTOME MRNA EDITING C TO U CONVERSION | 8 | 1.36e-01 | 3.04e-01 | 3.82e-01 |
| REACTOME SIGNALING BY MET | 78 | 1.37e-01 | -9.75e-02 | 3.82e-01 |
| REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES | 77 | 1.37e-01 | -9.81e-02 | 3.82e-01 |
| REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR | 24 | 1.39e-01 | 1.75e-01 | 3.87e-01 |
| REACTOME MET ACTIVATES PTPN11 | 5 | 1.39e-01 | 3.82e-01 | 3.87e-01 |
| REACTOME INTERLEUKIN 35 SIGNALLING | 12 | 1.40e-01 | 2.46e-01 | 3.89e-01 |
| REACTOME SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS | 43 | 1.40e-01 | -1.30e-01 | 3.89e-01 |
| REACTOME BH3 ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI APOPTOTIC BCL 2 MEMBERS | 9 | 1.40e-01 | 2.84e-01 | 3.89e-01 |
| REACTOME CROSSLINKING OF COLLAGEN FIBRILS | 16 | 1.40e-01 | -2.13e-01 | 3.89e-01 |
| REACTOME SELECTIVE AUTOPHAGY | 79 | 1.41e-01 | 9.59e-02 | 3.89e-01 |
| REACTOME FATTY ACIDS BOUND TO GPR40 FFAR1 REGULATE INSULIN SECRETION | 8 | 1.41e-01 | -3.00e-01 | 3.90e-01 |
| REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY | 25 | 1.42e-01 | 1.70e-01 | 3.90e-01 |
| REACTOME PRE NOTCH EXPRESSION AND PROCESSING | 112 | 1.42e-01 | 8.03e-02 | 3.90e-01 |
| REACTOME PLASMA LIPOPROTEIN REMODELING | 33 | 1.42e-01 | -1.48e-01 | 3.91e-01 |
| REACTOME CATION COUPLED CHLORIDE COTRANSPORTERS | 7 | 1.43e-01 | -3.20e-01 | 3.91e-01 |
| REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | 20 | 1.43e-01 | 1.89e-01 | 3.91e-01 |
| REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING | 34 | 1.43e-01 | 1.45e-01 | 3.91e-01 |
| REACTOME SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL | 25 | 1.44e-01 | -1.69e-01 | 3.92e-01 |
| REACTOME STAT3 NUCLEAR EVENTS DOWNSTREAM OF ALK SIGNALING | 9 | 1.44e-01 | 2.81e-01 | 3.93e-01 |
| REACTOME DNA DAMAGE BYPASS | 47 | 1.46e-01 | 1.23e-01 | 3.95e-01 |
| REACTOME DAG AND IP3 SIGNALING | 40 | 1.46e-01 | -1.33e-01 | 3.95e-01 |
| REACTOME CARDIAC CONDUCTION | 125 | 1.46e-01 | -7.53e-02 | 3.95e-01 |
| REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1 | 16 | 1.46e-01 | 2.10e-01 | 3.95e-01 |
| REACTOME MISCELLANEOUS TRANSPORT AND BINDING EVENTS | 24 | 1.46e-01 | -1.71e-01 | 3.96e-01 |
| REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | 89 | 1.47e-01 | -8.90e-02 | 3.96e-01 |
| REACTOME ONCOGENIC MAPK SIGNALING | 79 | 1.47e-01 | -9.44e-02 | 3.96e-01 |
| REACTOME LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS | 19 | 1.48e-01 | 1.92e-01 | 3.96e-01 |
| REACTOME DEATH RECEPTOR SIGNALING | 143 | 1.48e-01 | -7.01e-02 | 3.96e-01 |
| REACTOME PKA ACTIVATION IN GLUCAGON SIGNALLING | 17 | 1.48e-01 | -2.03e-01 | 3.97e-01 |
| REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | 11 | 1.48e-01 | -2.52e-01 | 3.97e-01 |
| REACTOME FORMATION OF AXIAL MESODERM | 14 | 1.52e-01 | 2.21e-01 | 4.05e-01 |
| REACTOME SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA | 52 | 1.53e-01 | -1.15e-01 | 4.08e-01 |
| REACTOME HYALURONAN UPTAKE AND DEGRADATION | 12 | 1.53e-01 | 2.38e-01 | 4.08e-01 |
| REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | 8 | 1.54e-01 | 2.91e-01 | 4.09e-01 |
| REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS | 33 | 1.55e-01 | 1.43e-01 | 4.10e-01 |
| REACTOME DEFECTIVE CSF2RB CAUSES SMDP5 | 7 | 1.55e-01 | -3.11e-01 | 4.10e-01 |
| REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL | 13 | 1.56e-01 | -2.27e-01 | 4.11e-01 |
| REACTOME TRANSPORT AND SYNTHESIS OF PAPS | 6 | 1.56e-01 | -3.35e-01 | 4.11e-01 |
| REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | 31 | 1.56e-01 | 1.47e-01 | 4.11e-01 |
| REACTOME TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA | 36 | 1.56e-01 | 1.37e-01 | 4.11e-01 |
| REACTOME TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS | 52 | 1.57e-01 | 1.14e-01 | 4.11e-01 |
| REACTOME ATTACHMENT AND ENTRY | 16 | 1.58e-01 | -2.04e-01 | 4.15e-01 |
| REACTOME DISEASES OF MITOTIC CELL CYCLE | 37 | 1.59e-01 | 1.34e-01 | 4.15e-01 |
| REACTOME DISORDERS OF TRANSMEMBRANE TRANSPORTERS | 170 | 1.60e-01 | 6.24e-02 | 4.19e-01 |
| REACTOME ATTENUATION PHASE | 27 | 1.62e-01 | 1.55e-01 | 4.23e-01 |
| REACTOME TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE | 39 | 1.63e-01 | 1.29e-01 | 4.23e-01 |
| REACTOME SIGNALING BY PDGF | 57 | 1.63e-01 | -1.07e-01 | 4.23e-01 |
| REACTOME ACTIVATED NTRK3 SIGNALS THROUGH RAS | 8 | 1.63e-01 | -2.85e-01 | 4.23e-01 |
| REACTOME HDMS DEMETHYLATE HISTONES | 40 | 1.63e-01 | 1.27e-01 | 4.24e-01 |
| REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE | 109 | 1.64e-01 | 7.71e-02 | 4.24e-01 |
| REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE | 37 | 1.65e-01 | -1.32e-01 | 4.24e-01 |
| REACTOME TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS | 55 | 1.65e-01 | 1.08e-01 | 4.24e-01 |
| REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | 20 | 1.65e-01 | -1.79e-01 | 4.24e-01 |
| REACTOME PLASMA LIPOPROTEIN ASSEMBLY | 19 | 1.65e-01 | -1.84e-01 | 4.25e-01 |
| REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | 13 | 1.65e-01 | 2.22e-01 | 4.25e-01 |
| REACTOME PEXOPHAGY | 11 | 1.66e-01 | 2.41e-01 | 4.26e-01 |
| REACTOME VITAMINS | 6 | 1.66e-01 | 3.26e-01 | 4.26e-01 |
| REACTOME PHOSPHORYLATION OF THE APC C | 20 | 1.67e-01 | 1.79e-01 | 4.26e-01 |
| REACTOME SIGNALING BY FGFR | 85 | 1.67e-01 | 8.67e-02 | 4.26e-01 |
| REACTOME TAK1 DEPENDENT IKK AND NF KAPPA B ACTIVATION | 41 | 1.67e-01 | 1.25e-01 | 4.26e-01 |
| REACTOME ANCHORING FIBRIL FORMATION | 13 | 1.67e-01 | -2.21e-01 | 4.26e-01 |
| REACTOME GPVI MEDIATED ACTIVATION CASCADE | 35 | 1.67e-01 | 1.35e-01 | 4.26e-01 |
| REACTOME CROSS PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS PHAGOSOMES | 6 | 1.68e-01 | -3.25e-01 | 4.26e-01 |
| REACTOME SURFACTANT METABOLISM | 28 | 1.68e-01 | -1.51e-01 | 4.26e-01 |
| REACTOME PEPTIDE LIGAND BINDING RECEPTORS | 188 | 1.68e-01 | 5.83e-02 | 4.26e-01 |
| REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE | 8 | 1.69e-01 | -2.81e-01 | 4.26e-01 |
| REACTOME SOS MEDIATED SIGNALLING | 7 | 1.69e-01 | -3.00e-01 | 4.26e-01 |
| REACTOME COENZYME A BIOSYNTHESIS | 8 | 1.69e-01 | 2.81e-01 | 4.26e-01 |
| REACTOME RESOLUTION OF ABASIC SITES AP SITES | 38 | 1.69e-01 | 1.29e-01 | 4.26e-01 |
| REACTOME VIRAL MESSENGER RNA SYNTHESIS | 44 | 1.71e-01 | 1.19e-01 | 4.28e-01 |
| REACTOME ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS | 7 | 1.71e-01 | -2.99e-01 | 4.28e-01 |
| REACTOME G PROTEIN ACTIVATION | 24 | 1.71e-01 | 1.61e-01 | 4.28e-01 |
| REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS | 13 | 1.72e-01 | -2.19e-01 | 4.30e-01 |
| REACTOME TERMINATION OF TRANSLESION DNA SYNTHESIS | 32 | 1.73e-01 | 1.39e-01 | 4.32e-01 |
| REACTOME LYSOSPHINGOLIPID AND LPA RECEPTORS | 14 | 1.73e-01 | 2.10e-01 | 4.32e-01 |
| REACTOME SIGNALING BY RETINOIC ACID | 41 | 1.74e-01 | 1.23e-01 | 4.33e-01 |
| REACTOME METABOLISM OF STEROIDS | 150 | 1.74e-01 | -6.43e-02 | 4.33e-01 |
| REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE | 52 | 1.75e-01 | 1.09e-01 | 4.33e-01 |
| REACTOME HYALURONAN METABOLISM | 17 | 1.75e-01 | 1.90e-01 | 4.34e-01 |
| REACTOME HIV TRANSCRIPTION ELONGATION | 42 | 1.76e-01 | 1.21e-01 | 4.34e-01 |
| REACTOME CREB3 FACTORS ACTIVATE GENES | 8 | 1.76e-01 | 2.76e-01 | 4.34e-01 |
| REACTOME O LINKED GLYCOSYLATION | 109 | 1.76e-01 | -7.50e-02 | 4.34e-01 |
| REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX | 19 | 1.76e-01 | 1.79e-01 | 4.34e-01 |
| REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS | 5 | 1.76e-01 | -3.49e-01 | 4.34e-01 |
| REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE | 69 | 1.77e-01 | -9.40e-02 | 4.34e-01 |
| REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | 23 | 1.77e-01 | -1.63e-01 | 4.34e-01 |
| REACTOME ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION | 16 | 1.78e-01 | 1.95e-01 | 4.35e-01 |
| REACTOME TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS | 43 | 1.78e-01 | 1.19e-01 | 4.35e-01 |
| REACTOME SIGNALING BY SCF KIT | 42 | 1.79e-01 | 1.20e-01 | 4.36e-01 |
| REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF | 53 | 1.79e-01 | -1.07e-01 | 4.36e-01 |
| REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL | 12 | 1.79e-01 | 2.24e-01 | 4.36e-01 |
| REACTOME ESTABLISHMENT OF SISTER CHROMATID COHESION | 9 | 1.80e-01 | 2.58e-01 | 4.36e-01 |
| REACTOME FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS | 8 | 1.80e-01 | 2.74e-01 | 4.36e-01 |
| REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | 9 | 1.80e-01 | -2.58e-01 | 4.36e-01 |
| REACTOME METABOLISM OF NUCLEOTIDES | 94 | 1.80e-01 | 8.00e-02 | 4.36e-01 |
| REACTOME FLT3 SIGNALING IN DISEASE | 28 | 1.82e-01 | 1.46e-01 | 4.39e-01 |
| REACTOME FORMATION OF LATERAL PLATE MESODERM | 5 | 1.83e-01 | 3.44e-01 | 4.42e-01 |
| REACTOME REDUCTION OF CYTOSOLIC CA LEVELS | 11 | 1.84e-01 | -2.31e-01 | 4.44e-01 |
| REACTOME C TYPE LECTIN RECEPTORS CLRS | 136 | 1.85e-01 | 6.58e-02 | 4.45e-01 |
| REACTOME ERBB2 REGULATES CELL MOTILITY | 15 | 1.85e-01 | 1.98e-01 | 4.45e-01 |
| REACTOME INTERLEUKIN 1 PROCESSING | 9 | 1.86e-01 | 2.55e-01 | 4.45e-01 |
| REACTOME GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER | 25 | 1.87e-01 | 1.53e-01 | 4.47e-01 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS | 9 | 1.88e-01 | -2.54e-01 | 4.48e-01 |
| REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3 | 679 | 1.88e-01 | 2.96e-02 | 4.48e-01 |
| REACTOME NEUROTRANSMITTER RELEASE CYCLE | 48 | 1.88e-01 | 1.10e-01 | 4.48e-01 |
| REACTOME MET ACTIVATES PI3K AKT SIGNALING | 6 | 1.89e-01 | 3.10e-01 | 4.49e-01 |
| REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | 16 | 1.89e-01 | 1.90e-01 | 4.49e-01 |
| REACTOME ASPARAGINE N LINKED GLYCOSYLATION | 299 | 1.90e-01 | 4.41e-02 | 4.50e-01 |
| REACTOME PI3K AKT SIGNALING IN CANCER | 103 | 1.90e-01 | 7.47e-02 | 4.50e-01 |
| REACTOME HDL ASSEMBLY | 8 | 1.91e-01 | -2.67e-01 | 4.50e-01 |
| REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY DVL INTERACTING PROTEINS | 5 | 1.91e-01 | -3.38e-01 | 4.50e-01 |
| REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE | 19 | 1.93e-01 | 1.72e-01 | 4.54e-01 |
| REACTOME RESPONSE TO METAL IONS | 14 | 1.93e-01 | 2.01e-01 | 4.54e-01 |
| REACTOME SIGNALING BY ALK | 26 | 1.93e-01 | 1.47e-01 | 4.54e-01 |
| REACTOME BUDDING AND MATURATION OF HIV VIRION | 28 | 1.93e-01 | 1.42e-01 | 4.54e-01 |
| REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS | 6 | 1.94e-01 | 3.06e-01 | 4.54e-01 |
| REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES | 16 | 1.94e-01 | 1.88e-01 | 4.54e-01 |
| REACTOME ACTIVATION OF RAS IN B CELLS | 5 | 1.95e-01 | -3.35e-01 | 4.56e-01 |
| REACTOME METHYLATION | 14 | 1.95e-01 | 2.00e-01 | 4.56e-01 |
| REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | 15 | 1.96e-01 | -1.93e-01 | 4.58e-01 |
| REACTOME CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND | 16 | 1.97e-01 | 1.86e-01 | 4.59e-01 |
| REACTOME RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK | 47 | 1.98e-01 | 1.09e-01 | 4.60e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION BY E2F6 | 32 | 1.98e-01 | 1.31e-01 | 4.60e-01 |
| REACTOME CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS | 19 | 1.99e-01 | 1.70e-01 | 4.62e-01 |
| REACTOME SENSORY PROCESSING OF SOUND | 72 | 2.00e-01 | -8.73e-02 | 4.63e-01 |
| REACTOME RECYCLING OF BILE ACIDS AND SALTS | 18 | 2.00e-01 | -1.74e-01 | 4.63e-01 |
| REACTOME RUNX2 REGULATES CHONDROCYTE MATURATION | 5 | 2.02e-01 | -3.30e-01 | 4.66e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES | 43 | 2.02e-01 | 1.12e-01 | 4.66e-01 |
| REACTOME METABOLISM OF STEROID HORMONES | 35 | 2.03e-01 | -1.24e-01 | 4.66e-01 |
| REACTOME FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES | 29 | 2.03e-01 | 1.37e-01 | 4.66e-01 |
| REACTOME TRAF6 MEDIATED NF KB ACTIVATION | 24 | 2.03e-01 | 1.50e-01 | 4.66e-01 |
| REACTOME PURINE SALVAGE | 12 | 2.05e-01 | 2.12e-01 | 4.67e-01 |
| REACTOME SIGNALING BY LRP5 MUTANTS | 6 | 2.05e-01 | 2.99e-01 | 4.67e-01 |
| REACTOME CA DEPENDENT EVENTS | 36 | 2.05e-01 | -1.22e-01 | 4.67e-01 |
| REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | 51 | 2.05e-01 | 1.03e-01 | 4.67e-01 |
| REACTOME WAX AND PLASMALOGEN BIOSYNTHESIS | 5 | 2.05e-01 | 3.27e-01 | 4.67e-01 |
| REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | 36 | 2.05e-01 | 1.22e-01 | 4.67e-01 |
| REACTOME DNA STRAND ELONGATION | 31 | 2.06e-01 | 1.31e-01 | 4.67e-01 |
| REACTOME APOPTOTIC EXECUTION PHASE | 49 | 2.06e-01 | 1.04e-01 | 4.68e-01 |
| REACTOME RHOG GTPASE CYCLE | 71 | 2.07e-01 | -8.66e-02 | 4.70e-01 |
| REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS | 16 | 2.09e-01 | -1.81e-01 | 4.73e-01 |
| REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | 20 | 2.11e-01 | 1.62e-01 | 4.76e-01 |
| REACTOME IRS ACTIVATION | 5 | 2.11e-01 | -3.23e-01 | 4.77e-01 |
| REACTOME GLYCEROPHOSPHOLIPID CATABOLISM | 7 | 2.11e-01 | -2.73e-01 | 4.77e-01 |
| REACTOME DISEASES OF METABOLISM | 237 | 2.12e-01 | -4.71e-02 | 4.78e-01 |
| REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | 10 | 2.13e-01 | -2.27e-01 | 4.79e-01 |
| REACTOME CILIUM ASSEMBLY | 190 | 2.13e-01 | 5.24e-02 | 4.79e-01 |
| REACTOME NOD1 2 SIGNALING PATHWAY | 33 | 2.14e-01 | 1.25e-01 | 4.80e-01 |
| REACTOME MATURATION OF SARS COV 2 SPIKE PROTEIN | 35 | 2.15e-01 | 1.21e-01 | 4.82e-01 |
| REACTOME ABACAVIR ADME | 9 | 2.18e-01 | 2.37e-01 | 4.88e-01 |
| REACTOME SIGNALING BY ERBB2 IN CANCER | 26 | 2.18e-01 | 1.39e-01 | 4.88e-01 |
| REACTOME PARACETAMOL ADME | 26 | 2.19e-01 | -1.39e-01 | 4.88e-01 |
| REACTOME METABOLISM OF INGESTED SEMET SEC MESEC INTO H2SE | 7 | 2.19e-01 | 2.68e-01 | 4.88e-01 |
| REACTOME KETONE BODY METABOLISM | 9 | 2.20e-01 | -2.36e-01 | 4.88e-01 |
| REACTOME G2 PHASE | 5 | 2.20e-01 | 3.17e-01 | 4.88e-01 |
| REACTOME MET INTERACTS WITH TNS PROTEINS | 5 | 2.20e-01 | -3.17e-01 | 4.88e-01 |
| REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | 21 | 2.22e-01 | 1.54e-01 | 4.92e-01 |
| REACTOME DISINHIBITION OF SNARE FORMATION | 5 | 2.23e-01 | 3.15e-01 | 4.93e-01 |
| REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX | 21 | 2.25e-01 | -1.53e-01 | 4.96e-01 |
| REACTOME NUCLEAR SIGNALING BY ERBB4 | 32 | 2.25e-01 | 1.24e-01 | 4.96e-01 |
| REACTOME LYSOSOME VESICLE BIOGENESIS | 33 | 2.25e-01 | 1.22e-01 | 4.96e-01 |
| REACTOME DRUG ADME | 103 | 2.26e-01 | -6.91e-02 | 4.96e-01 |
| REACTOME G PROTEIN MEDIATED EVENTS | 53 | 2.28e-01 | -9.58e-02 | 5.00e-01 |
| REACTOME PURINE CATABOLISM | 17 | 2.31e-01 | 1.68e-01 | 5.07e-01 |
| REACTOME P2Y RECEPTORS | 9 | 2.32e-01 | -2.30e-01 | 5.08e-01 |
| REACTOME MAPK FAMILY SIGNALING CASCADES | 314 | 2.32e-01 | 3.92e-02 | 5.08e-01 |
| REACTOME TYROSINE CATABOLISM | 5 | 2.33e-01 | -3.08e-01 | 5.08e-01 |
| REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | 62 | 2.33e-01 | -8.75e-02 | 5.09e-01 |
| REACTOME PRE NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM | 6 | 2.34e-01 | -2.81e-01 | 5.10e-01 |
| REACTOME SYNTHESIS OF 5 EICOSATETRAENOIC ACIDS | 9 | 2.35e-01 | 2.29e-01 | 5.11e-01 |
| REACTOME TOXICITY OF BOTULINUM TOXIN TYPE D BOTD | 5 | 2.35e-01 | 3.07e-01 | 5.12e-01 |
| REACTOME ANTIMICROBIAL PEPTIDES | 76 | 2.37e-01 | 7.84e-02 | 5.14e-01 |
| REACTOME RECEPTOR MEDIATED MITOPHAGY | 10 | 2.37e-01 | -2.16e-01 | 5.14e-01 |
| REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12 | 22 | 2.37e-01 | 1.46e-01 | 5.14e-01 |
| REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM | 50 | 2.38e-01 | -9.64e-02 | 5.15e-01 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES | 8 | 2.38e-01 | 2.41e-01 | 5.15e-01 |
| REACTOME DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B | 7 | 2.38e-01 | -2.57e-01 | 5.15e-01 |
| REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS | 35 | 2.40e-01 | 1.15e-01 | 5.17e-01 |
| REACTOME FATTY ACYL COA BIOSYNTHESIS | 36 | 2.41e-01 | -1.13e-01 | 5.17e-01 |
| REACTOME RHO GTPASES ACTIVATE WASPS AND WAVES | 34 | 2.41e-01 | 1.16e-01 | 5.17e-01 |
| REACTOME BETA OXIDATION OF BUTANOYL COA TO ACETYL COA | 5 | 2.41e-01 | -3.03e-01 | 5.17e-01 |
| REACTOME TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE | 20 | 2.42e-01 | 1.51e-01 | 5.17e-01 |
| REACTOME LAGGING STRAND SYNTHESIS | 19 | 2.42e-01 | 1.55e-01 | 5.17e-01 |
| REACTOME SIGNALING BY EGFR | 49 | 2.42e-01 | 9.66e-02 | 5.17e-01 |
| REACTOME REGULATION OF BETA CELL DEVELOPMENT | 41 | 2.42e-01 | 1.06e-01 | 5.17e-01 |
| REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING | 25 | 2.43e-01 | 1.35e-01 | 5.17e-01 |
| REACTOME BETA DEFENSINS | 27 | 2.43e-01 | 1.30e-01 | 5.17e-01 |
| REACTOME ASPARTATE AND ASPARAGINE METABOLISM | 11 | 2.43e-01 | 2.03e-01 | 5.17e-01 |
| REACTOME FATTY ACID METABOLISM | 170 | 2.44e-01 | -5.18e-02 | 5.18e-01 |
| REACTOME RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION | 8 | 2.45e-01 | -2.37e-01 | 5.19e-01 |
| REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 44 | 2.45e-01 | 1.01e-01 | 5.19e-01 |
| REACTOME CD22 MEDIATED BCR REGULATION | 5 | 2.45e-01 | 3.00e-01 | 5.19e-01 |
| REACTOME N GLYCAN TRIMMING AND ELONGATION IN THE CIS GOLGI | 5 | 2.46e-01 | 3.00e-01 | 5.19e-01 |
| REACTOME TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION | 5 | 2.48e-01 | 2.98e-01 | 5.24e-01 |
| REACTOME METABOLISM OF FOLATE AND PTERINES | 17 | 2.50e-01 | -1.61e-01 | 5.25e-01 |
| REACTOME SYNTHESIS OF PI | 5 | 2.50e-01 | -2.97e-01 | 5.25e-01 |
| REACTOME ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS | 87 | 2.50e-01 | -7.13e-02 | 5.25e-01 |
| REACTOME NUCLEAR IMPORT OF REV PROTEIN | 34 | 2.50e-01 | 1.14e-01 | 5.25e-01 |
| REACTOME DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS | 19 | 2.51e-01 | 1.52e-01 | 5.25e-01 |
| REACTOME REGULATION OF KIT SIGNALING | 16 | 2.51e-01 | 1.66e-01 | 5.25e-01 |
| REACTOME TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS | 29 | 2.51e-01 | 1.23e-01 | 5.25e-01 |
| REACTOME ACTIVATED NTRK3 SIGNALS THROUGH PI3K | 6 | 2.51e-01 | -2.70e-01 | 5.25e-01 |
| REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | 55 | 2.52e-01 | 8.94e-02 | 5.25e-01 |
| REACTOME SEMAPHORIN INTERACTIONS | 61 | 2.53e-01 | -8.47e-02 | 5.26e-01 |
| REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC | 198 | 2.54e-01 | 4.70e-02 | 5.28e-01 |
| REACTOME AGGREPHAGY | 42 | 2.56e-01 | 1.01e-01 | 5.31e-01 |
| REACTOME POTASSIUM CHANNELS | 102 | 2.56e-01 | -6.51e-02 | 5.32e-01 |
| REACTOME NUCLEAR ENVELOPE BREAKDOWN | 52 | 2.56e-01 | 9.10e-02 | 5.32e-01 |
| REACTOME TP53 REGULATES METABOLIC GENES | 81 | 2.58e-01 | 7.28e-02 | 5.33e-01 |
| REACTOME NTRK2 ACTIVATES RAC1 | 5 | 2.58e-01 | 2.92e-01 | 5.34e-01 |
| REACTOME CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE | 49 | 2.59e-01 | 9.33e-02 | 5.34e-01 |
| REACTOME RESOLUTION OF D LOOP STRUCTURES | 33 | 2.59e-01 | 1.14e-01 | 5.34e-01 |
| REACTOME SYNTHESIS OF KETONE BODIES | 8 | 2.59e-01 | -2.30e-01 | 5.34e-01 |
| REACTOME CHREBP ACTIVATES METABOLIC GENE EXPRESSION | 8 | 2.59e-01 | -2.30e-01 | 5.34e-01 |
| REACTOME DEFECTIVE GALNT3 CAUSES HFTC | 16 | 2.60e-01 | -1.63e-01 | 5.34e-01 |
| REACTOME CALCITONIN LIKE LIGAND RECEPTORS | 10 | 2.60e-01 | 2.06e-01 | 5.34e-01 |
| REACTOME NUCLEOTIDE BIOSYNTHESIS | 14 | 2.61e-01 | 1.74e-01 | 5.34e-01 |
| REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES | 255 | 2.61e-01 | -4.09e-02 | 5.34e-01 |
| REACTOME SPRY REGULATION OF FGF SIGNALING | 16 | 2.62e-01 | 1.62e-01 | 5.36e-01 |
| REACTOME ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING | 9 | 2.63e-01 | 2.15e-01 | 5.38e-01 |
| REACTOME DEADENYLATION OF MRNA | 25 | 2.64e-01 | 1.29e-01 | 5.38e-01 |
| REACTOME ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS | 5 | 2.66e-01 | -2.88e-01 | 5.41e-01 |
| REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | 48 | 2.66e-01 | -9.28e-02 | 5.41e-01 |
| REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | 30 | 2.66e-01 | -1.17e-01 | 5.41e-01 |
| REACTOME NUCLEAR ENVELOPE NE REASSEMBLY | 74 | 2.67e-01 | 7.47e-02 | 5.41e-01 |
| REACTOME TRIGLYCERIDE METABOLISM | 35 | 2.67e-01 | 1.08e-01 | 5.42e-01 |
| REACTOME TRIF MEDIATED PROGRAMMED CELL DEATH | 9 | 2.68e-01 | 2.13e-01 | 5.42e-01 |
| REACTOME SIGNALING BY FGFR4 IN DISEASE | 11 | 2.68e-01 | -1.93e-01 | 5.42e-01 |
| REACTOME KERATAN SULFATE BIOSYNTHESIS | 28 | 2.69e-01 | -1.21e-01 | 5.42e-01 |
| REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1 | 25 | 2.69e-01 | 1.28e-01 | 5.42e-01 |
| REACTOME MATURATION OF PROTEIN 3A | 9 | 2.69e-01 | -2.13e-01 | 5.42e-01 |
| REACTOME NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY | 6 | 2.69e-01 | -2.60e-01 | 5.42e-01 |
| REACTOME SIGNALING BY GPCR | 673 | 2.70e-01 | -2.50e-02 | 5.42e-01 |
| REACTOME UPTAKE AND FUNCTION OF ANTHRAX TOXINS | 11 | 2.71e-01 | -1.92e-01 | 5.43e-01 |
| REACTOME L1CAM INTERACTIONS | 112 | 2.71e-01 | -6.02e-02 | 5.43e-01 |
| REACTOME POLB DEPENDENT LONG PATCH BASE EXCISION REPAIR | 8 | 2.73e-01 | 2.24e-01 | 5.46e-01 |
| REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | 14 | 2.73e-01 | 1.69e-01 | 5.46e-01 |
| REACTOME PLATELET AGGREGATION PLUG FORMATION | 39 | 2.73e-01 | -1.01e-01 | 5.46e-01 |
| REACTOME RHOJ GTPASE CYCLE | 51 | 2.75e-01 | -8.84e-02 | 5.47e-01 |
| REACTOME P38MAPK EVENTS | 13 | 2.75e-01 | -1.75e-01 | 5.47e-01 |
| REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY | 5 | 2.75e-01 | -2.82e-01 | 5.47e-01 |
| REACTOME RHOBTB2 GTPASE CYCLE | 22 | 2.76e-01 | 1.34e-01 | 5.48e-01 |
| REACTOME METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES | 33 | 2.77e-01 | -1.09e-01 | 5.49e-01 |
| REACTOME VESICLE MEDIATED TRANSPORT | 642 | 2.77e-01 | 2.51e-02 | 5.49e-01 |
| REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS | 5 | 2.79e-01 | 2.80e-01 | 5.51e-01 |
| REACTOME SIGNALING BY RECEPTOR TYROSINE KINASES | 507 | 2.79e-01 | 2.81e-02 | 5.51e-01 |
| REACTOME INTERLEUKIN 37 SIGNALING | 20 | 2.80e-01 | -1.40e-01 | 5.52e-01 |
| REACTOME FCGR ACTIVATION | 11 | 2.80e-01 | 1.88e-01 | 5.53e-01 |
| REACTOME NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 22 | 2.80e-01 | 1.33e-01 | 5.53e-01 |
| REACTOME SIGNALING BY NTRK3 TRKC | 17 | 2.82e-01 | -1.51e-01 | 5.56e-01 |
| REACTOME ANDROGEN BIOSYNTHESIS | 11 | 2.83e-01 | -1.87e-01 | 5.57e-01 |
| REACTOME DISEASES OF IMMUNE SYSTEM | 29 | 2.84e-01 | 1.15e-01 | 5.58e-01 |
| REACTOME ALK MUTANTS BIND TKIS | 12 | 2.85e-01 | 1.78e-01 | 5.58e-01 |
| REACTOME PREGNENOLONE BIOSYNTHESIS | 12 | 2.86e-01 | -1.78e-01 | 5.60e-01 |
| REACTOME PHASE 0 RAPID DEPOLARISATION | 31 | 2.86e-01 | -1.11e-01 | 5.60e-01 |
| REACTOME ERBB2 ACTIVATES PTK6 SIGNALING | 13 | 2.86e-01 | 1.71e-01 | 5.60e-01 |
| REACTOME ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY | 10 | 2.92e-01 | 1.92e-01 | 5.71e-01 |
| REACTOME SIGNALING BY PTK6 | 54 | 2.93e-01 | 8.28e-02 | 5.71e-01 |
| REACTOME GLYCOSAMINOGLYCAN METABOLISM | 118 | 2.94e-01 | -5.60e-02 | 5.72e-01 |
| REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK | 28 | 2.96e-01 | -1.14e-01 | 5.76e-01 |
| REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX IN CANCER | 8 | 2.98e-01 | 2.13e-01 | 5.77e-01 |
| REACTOME FASL CD95L SIGNALING | 5 | 2.98e-01 | 2.69e-01 | 5.77e-01 |
| REACTOME RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION | 6 | 2.98e-01 | 2.45e-01 | 5.77e-01 |
| REACTOME HDR THROUGH MMEJ ALT NHEJ | 12 | 2.99e-01 | 1.73e-01 | 5.78e-01 |
| REACTOME 2 LTR CIRCLE FORMATION | 7 | 2.99e-01 | 2.27e-01 | 5.78e-01 |
| REACTOME HUR ELAVL1 BINDS AND STABILIZES MRNA | 8 | 3.00e-01 | 2.12e-01 | 5.79e-01 |
| REACTOME METALLOTHIONEINS BIND METALS | 11 | 3.00e-01 | 1.81e-01 | 5.79e-01 |
| REACTOME HISTIDINE CATABOLISM | 8 | 3.01e-01 | -2.11e-01 | 5.80e-01 |
| REACTOME INLA MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS | 9 | 3.02e-01 | 1.99e-01 | 5.81e-01 |
| REACTOME MTOR SIGNALLING | 40 | 3.03e-01 | -9.42e-02 | 5.82e-01 |
| REACTOME INTERLEUKIN RECEPTOR SHC SIGNALING | 24 | 3.05e-01 | -1.21e-01 | 5.85e-01 |
| REACTOME MHC CLASS II ANTIGEN PRESENTATION | 121 | 3.05e-01 | 5.40e-02 | 5.85e-01 |
| REACTOME GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION | 30 | 3.05e-01 | 1.08e-01 | 5.85e-01 |
| REACTOME DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15 | 8 | 3.06e-01 | -2.09e-01 | 5.85e-01 |
| REACTOME TRAIL SIGNALING | 8 | 3.06e-01 | 2.09e-01 | 5.85e-01 |
| REACTOME SODIUM PROTON EXCHANGERS | 7 | 3.08e-01 | -2.23e-01 | 5.87e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS | 29 | 3.08e-01 | 1.09e-01 | 5.87e-01 |
| REACTOME CYTOSOLIC TRNA AMINOACYLATION | 22 | 3.08e-01 | 1.25e-01 | 5.87e-01 |
| REACTOME REGULATION OF NPAS4 GENE TRANSCRIPTION | 5 | 3.09e-01 | 2.63e-01 | 5.89e-01 |
| REACTOME NUCLEAR PORE COMPLEX NPC DISASSEMBLY | 36 | 3.10e-01 | 9.78e-02 | 5.89e-01 |
| REACTOME OTHER INTERLEUKIN SIGNALING | 24 | 3.11e-01 | -1.19e-01 | 5.90e-01 |
| REACTOME PYRUVATE METABOLISM | 29 | 3.12e-01 | 1.08e-01 | 5.92e-01 |
| REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | 19 | 3.13e-01 | 1.34e-01 | 5.93e-01 |
| REACTOME INTEGRATION OF PROVIRUS | 9 | 3.14e-01 | 1.94e-01 | 5.93e-01 |
| REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | 11 | 3.14e-01 | 1.75e-01 | 5.93e-01 |
| REACTOME HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS | 9 | 3.14e-01 | -1.94e-01 | 5.93e-01 |
| REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | 24 | 3.15e-01 | -1.19e-01 | 5.94e-01 |
| REACTOME ROLE OF ABL IN ROBO SLIT SIGNALING | 8 | 3.16e-01 | 2.05e-01 | 5.94e-01 |
| REACTOME PHASE 4 RESTING MEMBRANE POTENTIAL | 19 | 3.16e-01 | -1.33e-01 | 5.95e-01 |
| REACTOME AURKA ACTIVATION BY TPX2 | 69 | 3.17e-01 | 6.97e-02 | 5.95e-01 |
| REACTOME MITOCHONDRIAL CALCIUM ION TRANSPORT | 23 | 3.20e-01 | -1.20e-01 | 6.00e-01 |
| REACTOME LIGAND RECEPTOR INTERACTIONS | 8 | 3.20e-01 | 2.03e-01 | 6.00e-01 |
| REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS | 15 | 3.20e-01 | 1.48e-01 | 6.00e-01 |
| REACTOME UBIQUINOL BIOSYNTHESIS | 8 | 3.21e-01 | 2.03e-01 | 6.01e-01 |
| REACTOME DISEASES OF CARBOHYDRATE METABOLISM | 31 | 3.21e-01 | 1.03e-01 | 6.01e-01 |
| REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1 | 20 | 3.23e-01 | 1.28e-01 | 6.02e-01 |
| REACTOME FREE FATTY ACID RECEPTORS | 5 | 3.24e-01 | 2.55e-01 | 6.03e-01 |
| REACTOME SODIUM COUPLED PHOSPHATE COTRANSPORTERS | 5 | 3.24e-01 | -2.55e-01 | 6.03e-01 |
| REACTOME ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS | 20 | 3.24e-01 | 1.27e-01 | 6.03e-01 |
| REACTOME G ALPHA Z SIGNALLING EVENTS | 48 | 3.25e-01 | 8.21e-02 | 6.04e-01 |
| REACTOME WNT MEDIATED ACTIVATION OF DVL | 8 | 3.27e-01 | -2.00e-01 | 6.06e-01 |
| REACTOME TYSND1 CLEAVES PEROXISOMAL PROTEINS | 7 | 3.28e-01 | 2.14e-01 | 6.07e-01 |
| REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | 15 | 3.29e-01 | -1.46e-01 | 6.08e-01 |
| REACTOME MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS | 7 | 3.29e-01 | 2.13e-01 | 6.08e-01 |
| REACTOME INFLAMMASOMES | 21 | 3.30e-01 | 1.23e-01 | 6.10e-01 |
| REACTOME CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION | 24 | 3.31e-01 | 1.15e-01 | 6.10e-01 |
| REACTOME PHASE 2 PLATEAU PHASE | 14 | 3.31e-01 | -1.50e-01 | 6.10e-01 |
| REACTOME EPITHELIAL MESENCHYMAL TRANSITION EMT DURING GASTRULATION | 7 | 3.32e-01 | 2.12e-01 | 6.11e-01 |
| REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | 27 | 3.33e-01 | 1.08e-01 | 6.11e-01 |
| REACTOME INTRA GOLGI TRAFFIC | 43 | 3.34e-01 | 8.52e-02 | 6.11e-01 |
| REACTOME LATE SARS COV 2 INFECTION EVENTS | 67 | 3.34e-01 | 6.83e-02 | 6.11e-01 |
| REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS | 46 | 3.34e-01 | 8.23e-02 | 6.11e-01 |
| REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS | 68 | 3.34e-01 | 6.77e-02 | 6.11e-01 |
| REACTOME CELL CELL JUNCTION ORGANIZATION | 64 | 3.35e-01 | -6.97e-02 | 6.11e-01 |
| REACTOME CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY | 12 | 3.35e-01 | -1.61e-01 | 6.11e-01 |
| REACTOME RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA | 27 | 3.35e-01 | 1.07e-01 | 6.11e-01 |
| REACTOME PARASITE INFECTION | 57 | 3.35e-01 | 7.38e-02 | 6.11e-01 |
| REACTOME TRANSPORT OF FATTY ACIDS | 8 | 3.37e-01 | -1.96e-01 | 6.11e-01 |
| REACTOME UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN | 6 | 3.37e-01 | 2.26e-01 | 6.11e-01 |
| REACTOME ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA | 9 | 3.37e-01 | -1.85e-01 | 6.11e-01 |
| REACTOME INTERLEUKIN 18 SIGNALING | 8 | 3.37e-01 | -1.96e-01 | 6.11e-01 |
| REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | 23 | 3.37e-01 | -1.16e-01 | 6.11e-01 |
| REACTOME RAS PROCESSING | 22 | 3.37e-01 | 1.18e-01 | 6.11e-01 |
| REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK | 17 | 3.38e-01 | -1.34e-01 | 6.11e-01 |
| REACTOME HIV ELONGATION ARREST AND RECOVERY | 33 | 3.39e-01 | 9.62e-02 | 6.12e-01 |
| REACTOME SERINE BIOSYNTHESIS | 9 | 3.40e-01 | 1.84e-01 | 6.13e-01 |
| REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB | 5 | 3.40e-01 | 2.46e-01 | 6.13e-01 |
| REACTOME SYNTHESIS OF PG | 8 | 3.41e-01 | -1.95e-01 | 6.13e-01 |
| REACTOME DAP12 SIGNALING | 27 | 3.41e-01 | 1.06e-01 | 6.13e-01 |
| REACTOME RHOBTB3 ATPASE CYCLE | 8 | 3.41e-01 | -1.94e-01 | 6.13e-01 |
| REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION | 23 | 3.43e-01 | -1.14e-01 | 6.16e-01 |
| REACTOME POLYMERASE SWITCHING | 13 | 3.43e-01 | 1.52e-01 | 6.16e-01 |
| REACTOME MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION | 15 | 3.44e-01 | 1.41e-01 | 6.16e-01 |
| REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | 93 | 3.45e-01 | 5.67e-02 | 6.16e-01 |
| REACTOME RHOBTB GTPASE CYCLE | 34 | 3.45e-01 | 9.36e-02 | 6.16e-01 |
| REACTOME REGULATION OF INSULIN SECRETION | 77 | 3.47e-01 | -6.20e-02 | 6.18e-01 |
| REACTOME BIOSYNTHESIS OF MARESINS | 8 | 3.47e-01 | -1.92e-01 | 6.18e-01 |
| REACTOME ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS | 20 | 3.48e-01 | 1.21e-01 | 6.19e-01 |
| REACTOME PTK6 REGULATES CELL CYCLE | 6 | 3.49e-01 | 2.21e-01 | 6.21e-01 |
| REACTOME CYTOPROTECTION BY HMOX1 | 59 | 3.49e-01 | 7.04e-02 | 6.21e-01 |
| REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | 19 | 3.50e-01 | -1.24e-01 | 6.21e-01 |
| REACTOME EPHRIN SIGNALING | 17 | 3.51e-01 | -1.31e-01 | 6.21e-01 |
| REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | 15 | 3.51e-01 | -1.39e-01 | 6.21e-01 |
| REACTOME VOLTAGE GATED POTASSIUM CHANNELS | 42 | 3.52e-01 | -8.30e-02 | 6.21e-01 |
| REACTOME NUCLEOTIDE CATABOLISM | 35 | 3.52e-01 | 9.09e-02 | 6.21e-01 |
| REACTOME VITAMIN C ASCORBATE METABOLISM | 8 | 3.52e-01 | 1.90e-01 | 6.21e-01 |
| REACTOME CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY | 25 | 3.53e-01 | 1.07e-01 | 6.21e-01 |
| REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS | 14 | 3.53e-01 | -1.43e-01 | 6.21e-01 |
| REACTOME MISCELLANEOUS SUBSTRATES | 12 | 3.53e-01 | -1.55e-01 | 6.21e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION BY MECP2 | 60 | 3.54e-01 | 6.92e-02 | 6.22e-01 |
| REACTOME PI 3K CASCADE FGFR1 | 21 | 3.55e-01 | 1.17e-01 | 6.24e-01 |
| REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION | 20 | 3.56e-01 | 1.19e-01 | 6.24e-01 |
| REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES | 15 | 3.57e-01 | 1.37e-01 | 6.25e-01 |
| REACTOME INITIATION OF NUCLEAR ENVELOPE NE REFORMATION | 18 | 3.57e-01 | 1.25e-01 | 6.25e-01 |
| REACTOME EARLY PHASE OF HIV LIFE CYCLE | 14 | 3.58e-01 | 1.42e-01 | 6.25e-01 |
| REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | 13 | 3.58e-01 | 1.47e-01 | 6.25e-01 |
| REACTOME DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS | 25 | 3.58e-01 | 1.06e-01 | 6.25e-01 |
| REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE | 93 | 3.59e-01 | 5.51e-02 | 6.25e-01 |
| REACTOME SIGNAL TRANSDUCTION BY L1 | 20 | 3.59e-01 | -1.18e-01 | 6.25e-01 |
| REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE | 71 | 3.59e-01 | 6.29e-02 | 6.25e-01 |
| REACTOME RHO GTPASES ACTIVATE KTN1 | 11 | 3.60e-01 | -1.59e-01 | 6.25e-01 |
| REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS | 34 | 3.61e-01 | 9.06e-02 | 6.25e-01 |
| REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX | 32 | 3.61e-01 | 9.34e-02 | 6.25e-01 |
| REACTOME ACTIVATION OF SMO | 18 | 3.61e-01 | 1.24e-01 | 6.25e-01 |
| REACTOME SPERM MOTILITY AND TAXES | 9 | 3.61e-01 | -1.76e-01 | 6.25e-01 |
| REACTOME PHYSIOLOGICAL FACTORS | 14 | 3.61e-01 | 1.41e-01 | 6.25e-01 |
| REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING | 32 | 3.64e-01 | 9.27e-02 | 6.29e-01 |
| REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | 118 | 3.65e-01 | -4.82e-02 | 6.30e-01 |
| REACTOME SENSING OF DNA DOUBLE STRAND BREAKS | 6 | 3.67e-01 | 2.13e-01 | 6.32e-01 |
| REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX | 91 | 3.67e-01 | 5.47e-02 | 6.32e-01 |
| REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL | 41 | 3.69e-01 | 8.11e-02 | 6.34e-01 |
| REACTOME SARS COV 1 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS | 16 | 3.69e-01 | 1.30e-01 | 6.34e-01 |
| REACTOME SEMA4D IN SEMAPHORIN SIGNALING | 24 | 3.72e-01 | -1.05e-01 | 6.38e-01 |
| REACTOME SIGNALING BY MST1 | 5 | 3.72e-01 | -2.30e-01 | 6.38e-01 |
| REACTOME EICOSANOID LIGAND BINDING RECEPTORS | 14 | 3.74e-01 | 1.37e-01 | 6.41e-01 |
| REACTOME EXTRA NUCLEAR ESTROGEN SIGNALING | 74 | 3.75e-01 | 5.97e-02 | 6.41e-01 |
| REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | 23 | 3.80e-01 | -1.06e-01 | 6.48e-01 |
| REACTOME COPI MEDIATED ANTEROGRADE TRANSPORT | 101 | 3.80e-01 | 5.06e-02 | 6.48e-01 |
| REACTOME CIRCADIAN CLOCK | 68 | 3.80e-01 | 6.15e-02 | 6.48e-01 |
| REACTOME CREB PHOSPHORYLATION | 6 | 3.82e-01 | -2.06e-01 | 6.50e-01 |
| REACTOME AMINO ACID CONJUGATION | 9 | 3.82e-01 | -1.68e-01 | 6.50e-01 |
| REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | 11 | 3.82e-01 | -1.52e-01 | 6.50e-01 |
| REACTOME RHOT1 GTPASE CYCLE | 5 | 3.83e-01 | 2.25e-01 | 6.51e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION | 12 | 3.85e-01 | 1.45e-01 | 6.53e-01 |
| REACTOME INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS | 37 | 3.85e-01 | 8.25e-02 | 6.53e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES | 49 | 3.86e-01 | 7.16e-02 | 6.53e-01 |
| REACTOME MULTIFUNCTIONAL ANION EXCHANGERS | 9 | 3.87e-01 | -1.67e-01 | 6.54e-01 |
| REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K | 12 | 3.88e-01 | 1.44e-01 | 6.56e-01 |
| REACTOME MUCOPOLYSACCHARIDOSES | 10 | 3.91e-01 | -1.57e-01 | 6.59e-01 |
| REACTOME SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER | 54 | 3.92e-01 | 6.73e-02 | 6.60e-01 |
| REACTOME DEFECTIVE CHST3 CAUSES SEDCJD | 7 | 3.92e-01 | 1.87e-01 | 6.60e-01 |
| REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER | 49 | 3.94e-01 | 7.04e-02 | 6.63e-01 |
| REACTOME RHO GTPASE CYCLE | 423 | 3.94e-01 | -2.41e-02 | 6.63e-01 |
| REACTOME SIGNALING BY NTRK2 TRKB | 25 | 3.97e-01 | 9.79e-02 | 6.65e-01 |
| REACTOME THE NLRP3 INFLAMMASOME | 16 | 3.97e-01 | 1.22e-01 | 6.65e-01 |
| REACTOME ACETYLCHOLINE REGULATES INSULIN SECRETION | 10 | 3.97e-01 | -1.55e-01 | 6.65e-01 |
| REACTOME DAP12 INTERACTIONS | 37 | 3.98e-01 | 8.04e-02 | 6.65e-01 |
| REACTOME CRMPS IN SEMA3A SIGNALING | 15 | 3.98e-01 | -1.26e-01 | 6.65e-01 |
| REACTOME MRNA EDITING | 10 | 3.98e-01 | 1.54e-01 | 6.65e-01 |
| REACTOME INTERLEUKIN 2 SIGNALING | 11 | 3.99e-01 | 1.47e-01 | 6.66e-01 |
| REACTOME LEISHMANIA INFECTION | 156 | 3.99e-01 | 3.91e-02 | 6.66e-01 |
| REACTOME INTERLEUKIN 6 SIGNALING | 11 | 4.01e-01 | 1.46e-01 | 6.68e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN | 21 | 4.01e-01 | 1.06e-01 | 6.68e-01 |
| REACTOME HEME SIGNALING | 47 | 4.05e-01 | -7.02e-02 | 6.73e-01 |
| REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS | 312 | 4.06e-01 | 2.73e-02 | 6.74e-01 |
| REACTOME MELANIN BIOSYNTHESIS | 5 | 4.07e-01 | -2.14e-01 | 6.75e-01 |
| REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND | 14 | 4.10e-01 | 1.27e-01 | 6.79e-01 |
| REACTOME SUMOYLATION OF IMMUNE RESPONSE PROTEINS | 10 | 4.13e-01 | -1.49e-01 | 6.84e-01 |
| REACTOME NEUROTOXICITY OF CLOSTRIDIUM TOXINS | 10 | 4.14e-01 | 1.49e-01 | 6.85e-01 |
| REACTOME RRNA PROCESSING IN THE MITOCHONDRION | 9 | 4.14e-01 | -1.57e-01 | 6.85e-01 |
| REACTOME N GLYCAN ANTENNAE ELONGATION | 15 | 4.15e-01 | 1.21e-01 | 6.85e-01 |
| REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES | 78 | 4.16e-01 | 5.33e-02 | 6.85e-01 |
| REACTOME MET RECEPTOR RECYCLING | 10 | 4.16e-01 | 1.48e-01 | 6.85e-01 |
| REACTOME SIGNALING BY NOTCH1 | 69 | 4.16e-01 | 5.66e-02 | 6.85e-01 |
| REACTOME NEF AND SIGNAL TRANSDUCTION | 8 | 4.19e-01 | 1.65e-01 | 6.88e-01 |
| REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS | 16 | 4.20e-01 | 1.17e-01 | 6.89e-01 |
| REACTOME RAC2 GTPASE CYCLE | 81 | 4.20e-01 | -5.18e-02 | 6.90e-01 |
| REACTOME DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1 | 9 | 4.21e-01 | 1.55e-01 | 6.90e-01 |
| REACTOME ADHERENS JUNCTIONS INTERACTIONS | 33 | 4.22e-01 | -8.08e-02 | 6.90e-01 |
| REACTOME RHOU GTPASE CYCLE | 37 | 4.22e-01 | -7.63e-02 | 6.90e-01 |
| REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | 35 | 4.22e-01 | 7.83e-02 | 6.90e-01 |
| REACTOME ACYL CHAIN REMODELING OF CL | 5 | 4.23e-01 | 2.07e-01 | 6.90e-01 |
| REACTOME SARS COV 2 TARGETS PDZ PROTEINS IN CELL CELL JUNCTION | 5 | 4.23e-01 | 2.07e-01 | 6.90e-01 |
| REACTOME O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS | 38 | 4.24e-01 | -7.49e-02 | 6.90e-01 |
| REACTOME ACYL CHAIN REMODELING OF DAG AND TAG | 5 | 4.24e-01 | -2.06e-01 | 6.90e-01 |
| REACTOME PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE | 74 | 4.24e-01 | -5.37e-02 | 6.90e-01 |
| REACTOME SHC1 EVENTS IN ERBB2 SIGNALING | 22 | 4.25e-01 | 9.83e-02 | 6.90e-01 |
| REACTOME INTERLEUKIN 15 SIGNALING | 13 | 4.26e-01 | 1.28e-01 | 6.91e-01 |
| REACTOME DEGRADATION OF CYSTEINE AND HOMOCYSTEINE | 15 | 4.27e-01 | 1.19e-01 | 6.91e-01 |
| REACTOME CS DS DEGRADATION | 12 | 4.28e-01 | 1.32e-01 | 6.94e-01 |
| REACTOME PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1 | 9 | 4.29e-01 | 1.52e-01 | 6.94e-01 |
| REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING | 45 | 4.29e-01 | 6.81e-02 | 6.94e-01 |
| REACTOME ENOS ACTIVATION | 11 | 4.31e-01 | 1.37e-01 | 6.96e-01 |
| REACTOME RUNX3 REGULATES CDKN1A TRANSCRIPTION | 7 | 4.33e-01 | -1.71e-01 | 6.98e-01 |
| REACTOME PROLACTIN RECEPTOR SIGNALING | 15 | 4.35e-01 | -1.16e-01 | 7.01e-01 |
| REACTOME ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS | 17 | 4.36e-01 | 1.09e-01 | 7.02e-01 |
| REACTOME TRYPTOPHAN CATABOLISM | 14 | 4.37e-01 | -1.20e-01 | 7.03e-01 |
| REACTOME SIGNALING BY FGFR1 IN DISEASE | 38 | 4.38e-01 | -7.26e-02 | 7.04e-01 |
| REACTOME DEFECTS IN COBALAMIN B12 METABOLISM | 13 | 4.38e-01 | 1.24e-01 | 7.04e-01 |
| REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION | 6 | 4.40e-01 | 1.82e-01 | 7.05e-01 |
| REACTOME DEPOLYMERISATION OF THE NUCLEAR LAMINA | 14 | 4.42e-01 | 1.19e-01 | 7.05e-01 |
| REACTOME MAPK3 ERK1 ACTIVATION | 10 | 4.42e-01 | 1.40e-01 | 7.05e-01 |
| REACTOME RIP MEDIATED NFKB ACTIVATION VIA ZBP1 | 16 | 4.42e-01 | 1.11e-01 | 7.05e-01 |
| REACTOME EICOSANOIDS | 12 | 4.42e-01 | -1.28e-01 | 7.05e-01 |
| REACTOME DISSOLUTION OF FIBRIN CLOT | 13 | 4.42e-01 | -1.23e-01 | 7.05e-01 |
| REACTOME NEF MEDIATED CD4 DOWN REGULATION | 9 | 4.42e-01 | -1.48e-01 | 7.05e-01 |
| REACTOME FGFRL1 MODULATION OF FGFR1 SIGNALING | 13 | 4.43e-01 | 1.23e-01 | 7.05e-01 |
| REACTOME RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION | 22 | 4.45e-01 | 9.41e-02 | 7.08e-01 |
| REACTOME REGULATION BY C FLIP | 11 | 4.46e-01 | 1.33e-01 | 7.09e-01 |
| REACTOME INTERLEUKIN 20 FAMILY SIGNALING | 25 | 4.46e-01 | -8.80e-02 | 7.09e-01 |
| REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN | 32 | 4.47e-01 | 7.77e-02 | 7.09e-01 |
| REACTOME TNFR1 INDUCED PROAPOPTOTIC SIGNALING | 23 | 4.48e-01 | -9.13e-02 | 7.10e-01 |
| REACTOME FGFR1B LIGAND BINDING AND ACTIVATION | 6 | 4.51e-01 | -1.78e-01 | 7.13e-01 |
| REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | 10 | 4.51e-01 | 1.38e-01 | 7.13e-01 |
| REACTOME PI3K AKT ACTIVATION | 9 | 4.53e-01 | -1.45e-01 | 7.15e-01 |
| REACTOME RHO GTPASES ACTIVATE NADPH OXIDASES | 21 | 4.53e-01 | 9.45e-02 | 7.15e-01 |
| REACTOME DEFENSINS | 33 | 4.53e-01 | 7.54e-02 | 7.15e-01 |
| REACTOME EGFR INTERACTS WITH PHOSPHOLIPASE C GAMMA | 9 | 4.54e-01 | 1.44e-01 | 7.16e-01 |
| REACTOME SUMO IS PROTEOLYTICALLY PROCESSED | 6 | 4.56e-01 | 1.76e-01 | 7.17e-01 |
| REACTOME TLR3 MEDIATED TICAM1 DEPENDENT PROGRAMMED CELL DEATH | 6 | 4.56e-01 | 1.76e-01 | 7.17e-01 |
| REACTOME SIGNALLING TO RAS | 20 | 4.57e-01 | -9.61e-02 | 7.18e-01 |
| REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | 20 | 4.57e-01 | 9.60e-02 | 7.18e-01 |
| REACTOME GLYCOGEN METABOLISM | 22 | 4.58e-01 | 9.14e-02 | 7.18e-01 |
| REACTOME ATTACHMENT OF GPI ANCHOR TO UPAR | 7 | 4.58e-01 | 1.62e-01 | 7.18e-01 |
| REACTOME IRE1ALPHA ACTIVATES CHAPERONES | 48 | 4.59e-01 | -6.18e-02 | 7.19e-01 |
| REACTOME INACTIVATION OF CDC42 AND RAC1 | 8 | 4.60e-01 | -1.51e-01 | 7.19e-01 |
| REACTOME FGFR3B LIGAND BINDING AND ACTIVATION | 7 | 4.60e-01 | -1.61e-01 | 7.19e-01 |
| REACTOME ETHANOL OXIDATION | 12 | 4.64e-01 | -1.22e-01 | 7.23e-01 |
| REACTOME NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 11 | 4.64e-01 | 1.27e-01 | 7.24e-01 |
| REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III | 31 | 4.64e-01 | 7.59e-02 | 7.24e-01 |
| REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE | 22 | 4.65e-01 | -8.99e-02 | 7.24e-01 |
| REACTOME ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM | 12 | 4.66e-01 | 1.22e-01 | 7.24e-01 |
| REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | 91 | 4.67e-01 | 4.41e-02 | 7.25e-01 |
| REACTOME SMAC XIAP REGULATED APOPTOTIC RESPONSE | 7 | 4.67e-01 | 1.59e-01 | 7.25e-01 |
| REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | 24 | 4.68e-01 | 8.55e-02 | 7.25e-01 |
| REACTOME COMMON PATHWAY OF FIBRIN CLOT FORMATION | 21 | 4.68e-01 | -9.14e-02 | 7.25e-01 |
| REACTOME SUMOYLATION OF INTRACELLULAR RECEPTORS | 29 | 4.69e-01 | -7.78e-02 | 7.25e-01 |
| REACTOME PIWI INTERACTING RNA PIRNA BIOGENESIS | 29 | 4.69e-01 | -7.77e-02 | 7.25e-01 |
| REACTOME NETRIN 1 SIGNALING | 49 | 4.71e-01 | 5.95e-02 | 7.28e-01 |
| REACTOME SIGNALING BY ERBB2 | 50 | 4.72e-01 | 5.88e-02 | 7.28e-01 |
| REACTOME ALPHA DEFENSINS | 6 | 4.73e-01 | -1.69e-01 | 7.28e-01 |
| REACTOME REACTIONS SPECIFIC TO THE COMPLEX N GLYCAN SYNTHESIS PATHWAY | 10 | 4.73e-01 | -1.31e-01 | 7.28e-01 |
| REACTOME REPRESSION OF WNT TARGET GENES | 14 | 4.73e-01 | -1.11e-01 | 7.28e-01 |
| REACTOME LOSS OF FUNCTION OF SMAD2 3 IN CANCER | 7 | 4.73e-01 | 1.57e-01 | 7.28e-01 |
| REACTOME FCERI MEDIATED MAPK ACTIVATION | 32 | 4.76e-01 | 7.28e-02 | 7.31e-01 |
| REACTOME SHC MEDIATED CASCADE FGFR4 | 19 | 4.76e-01 | -9.44e-02 | 7.31e-01 |
| REACTOME ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY | 5 | 4.77e-01 | 1.84e-01 | 7.31e-01 |
| REACTOME PROCESSING AND ACTIVATION OF SUMO | 10 | 4.77e-01 | 1.30e-01 | 7.31e-01 |
| REACTOME REGULATION OF TP53 EXPRESSION AND DEGRADATION | 37 | 4.78e-01 | 6.74e-02 | 7.32e-01 |
| REACTOME KINESINS | 59 | 4.78e-01 | -5.33e-02 | 7.32e-01 |
| REACTOME RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION | 6 | 4.79e-01 | -1.67e-01 | 7.32e-01 |
| REACTOME SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX | 15 | 4.80e-01 | 1.05e-01 | 7.32e-01 |
| REACTOME ACTIVATION OF MATRIX METALLOPROTEINASES | 30 | 4.81e-01 | -7.43e-02 | 7.32e-01 |
| REACTOME CLEC7A INFLAMMASOME PATHWAY | 6 | 4.81e-01 | 1.66e-01 | 7.32e-01 |
| REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | 16 | 4.81e-01 | 1.02e-01 | 7.32e-01 |
| REACTOME INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE | 20 | 4.82e-01 | 9.09e-02 | 7.32e-01 |
| REACTOME SIGNALING BY ACTIVIN | 15 | 4.82e-01 | 1.05e-01 | 7.33e-01 |
| REACTOME SYNTHESIS OF GDP MANNOSE | 5 | 4.84e-01 | -1.81e-01 | 7.33e-01 |
| REACTOME ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS | 10 | 4.84e-01 | 1.28e-01 | 7.33e-01 |
| REACTOME CHL1 INTERACTIONS | 9 | 4.85e-01 | -1.34e-01 | 7.33e-01 |
| REACTOME ARYL HYDROCARBON RECEPTOR SIGNALLING | 6 | 4.85e-01 | 1.64e-01 | 7.33e-01 |
| REACTOME SLC TRANSPORTER DISORDERS | 94 | 4.85e-01 | -4.16e-02 | 7.33e-01 |
| REACTOME DOPAMINE RECEPTORS | 5 | 4.86e-01 | 1.80e-01 | 7.33e-01 |
| REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG | 7 | 4.86e-01 | 1.52e-01 | 7.33e-01 |
| REACTOME REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS | 7 | 4.86e-01 | -1.52e-01 | 7.33e-01 |
| REACTOME G PROTEIN BETA GAMMA SIGNALLING | 30 | 4.87e-01 | -7.34e-02 | 7.33e-01 |
| REACTOME IRF3 MEDIATED INDUCTION OF TYPE I IFN | 13 | 4.87e-01 | -1.11e-01 | 7.33e-01 |
| REACTOME INTERLEUKIN 21 SIGNALING | 9 | 4.88e-01 | 1.34e-01 | 7.33e-01 |
| REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY | 14 | 4.89e-01 | -1.07e-01 | 7.33e-01 |
| REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX | 39 | 4.89e-01 | 6.41e-02 | 7.33e-01 |
| REACTOME INDUCTION OF CELL CELL FUSION | 12 | 4.89e-01 | -1.15e-01 | 7.33e-01 |
| REACTOME DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS | 15 | 4.90e-01 | -1.03e-01 | 7.34e-01 |
| REACTOME HS GAG DEGRADATION | 19 | 4.91e-01 | -9.12e-02 | 7.34e-01 |
| REACTOME FRS MEDIATED FGFR4 SIGNALING | 21 | 4.91e-01 | -8.67e-02 | 7.34e-01 |
| REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS | 6 | 4.92e-01 | -1.62e-01 | 7.34e-01 |
| REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES | 34 | 4.92e-01 | 6.81e-02 | 7.35e-01 |
| REACTOME G ALPHA Q SIGNALLING EVENTS | 206 | 4.93e-01 | -2.77e-02 | 7.35e-01 |
| REACTOME SYNAPTIC ADHESION LIKE MOLECULES | 19 | 4.93e-01 | -9.08e-02 | 7.35e-01 |
| REACTOME PECAM1 INTERACTIONS | 12 | 4.94e-01 | 1.14e-01 | 7.35e-01 |
| REACTOME RUNX3 REGULATES YAP1 MEDIATED TRANSCRIPTION | 8 | 4.95e-01 | -1.39e-01 | 7.35e-01 |
| REACTOME PLATELET CALCIUM HOMEOSTASIS | 27 | 4.95e-01 | -7.59e-02 | 7.35e-01 |
| REACTOME FRS MEDIATED FGFR2 SIGNALING | 24 | 4.96e-01 | -8.03e-02 | 7.36e-01 |
| REACTOME RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES TREGS | 9 | 4.97e-01 | -1.31e-01 | 7.36e-01 |
| REACTOME SEMA3A PAK DEPENDENT AXON REPULSION | 14 | 4.97e-01 | -1.05e-01 | 7.36e-01 |
| REACTOME CA2 ACTIVATED K CHANNELS | 9 | 4.97e-01 | -1.31e-01 | 7.36e-01 |
| REACTOME INSULIN RECEPTOR SIGNALLING CASCADE | 53 | 4.98e-01 | -5.38e-02 | 7.36e-01 |
| REACTOME PROSTANOID LIGAND RECEPTORS | 9 | 5.00e-01 | 1.30e-01 | 7.38e-01 |
| REACTOME METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION | 15 | 5.00e-01 | 1.01e-01 | 7.38e-01 |
| REACTOME DEFECTS IN VITAMIN AND COFACTOR METABOLISM | 21 | 5.02e-01 | 8.46e-02 | 7.41e-01 |
| REACTOME FBXW7 MUTANTS AND NOTCH1 IN CANCER | 5 | 5.03e-01 | 1.73e-01 | 7.41e-01 |
| REACTOME RHO GTPASES ACTIVATE PAKS | 19 | 5.05e-01 | -8.84e-02 | 7.43e-01 |
| REACTOME DEFECTIVE CHST6 CAUSES MCDC1 | 8 | 5.05e-01 | -1.36e-01 | 7.43e-01 |
| REACTOME SHC MEDIATED CASCADE FGFR3 | 17 | 5.06e-01 | -9.32e-02 | 7.44e-01 |
| REACTOME EGFR TRANSACTIVATION BY GASTRIN | 9 | 5.07e-01 | -1.28e-01 | 7.45e-01 |
| REACTOME PLASMA LIPOPROTEIN CLEARANCE | 37 | 5.08e-01 | 6.30e-02 | 7.45e-01 |
| REACTOME SYNTHESIS OF PIPS AT THE ER MEMBRANE | 5 | 5.09e-01 | -1.70e-01 | 7.47e-01 |
| REACTOME RAC3 GTPASE CYCLE | 85 | 5.10e-01 | -4.14e-02 | 7.47e-01 |
| REACTOME DECTIN 2 FAMILY | 26 | 5.11e-01 | -7.44e-02 | 7.48e-01 |
| REACTOME G BETA GAMMA SIGNALLING THROUGH CDC42 | 19 | 5.15e-01 | 8.63e-02 | 7.53e-01 |
| REACTOME LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX | 5 | 5.16e-01 | 1.68e-01 | 7.53e-01 |
| REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | 183 | 5.16e-01 | 2.78e-02 | 7.53e-01 |
| REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | 19 | 5.17e-01 | 8.58e-02 | 7.54e-01 |
| REACTOME SUMOYLATION OF SUMOYLATION PROTEINS | 35 | 5.18e-01 | 6.32e-02 | 7.54e-01 |
| REACTOME MITOTIC TELOPHASE CYTOKINESIS | 11 | 5.18e-01 | 1.13e-01 | 7.54e-01 |
| REACTOME INTERLEUKIN 23 SIGNALING | 9 | 5.18e-01 | 1.24e-01 | 7.54e-01 |
| REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | 12 | 5.19e-01 | -1.08e-01 | 7.54e-01 |
| REACTOME NS1 MEDIATED EFFECTS ON HOST PATHWAYS | 41 | 5.21e-01 | 5.80e-02 | 7.56e-01 |
| REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION | 32 | 5.21e-01 | -6.55e-02 | 7.56e-01 |
| REACTOME FRS MEDIATED FGFR3 SIGNALING | 19 | 5.22e-01 | -8.49e-02 | 7.56e-01 |
| REACTOME DEFECTIVE B4GALT1 CAUSES B4GALT1 CDG CDG 2D | 8 | 5.22e-01 | -1.31e-01 | 7.56e-01 |
| REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | 14 | 5.24e-01 | -9.85e-02 | 7.57e-01 |
| REACTOME CONJUGATION OF BENZOATE WITH GLYCINE | 6 | 5.24e-01 | -1.50e-01 | 7.57e-01 |
| REACTOME DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE | 17 | 5.25e-01 | -8.89e-02 | 7.59e-01 |
| REACTOME CGMP EFFECTS | 16 | 5.27e-01 | -9.14e-02 | 7.60e-01 |
| REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | 17 | 5.27e-01 | -8.86e-02 | 7.60e-01 |
| REACTOME RHOV GTPASE CYCLE | 36 | 5.28e-01 | -6.07e-02 | 7.61e-01 |
| REACTOME DNA DAMAGE REVERSAL | 8 | 5.31e-01 | -1.28e-01 | 7.64e-01 |
| REACTOME PYRIMIDINE CATABOLISM | 12 | 5.32e-01 | 1.04e-01 | 7.65e-01 |
| REACTOME PEROXISOMAL LIPID METABOLISM | 28 | 5.33e-01 | 6.81e-02 | 7.65e-01 |
| REACTOME BIOTIN TRANSPORT AND METABOLISM | 10 | 5.35e-01 | -1.13e-01 | 7.68e-01 |
| REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | 9 | 5.37e-01 | -1.19e-01 | 7.70e-01 |
| REACTOME RET SIGNALING | 40 | 5.39e-01 | -5.62e-02 | 7.71e-01 |
| REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING | 12 | 5.39e-01 | -1.02e-01 | 7.71e-01 |
| REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | 14 | 5.40e-01 | 9.46e-02 | 7.72e-01 |
| REACTOME HEME BIOSYNTHESIS | 13 | 5.41e-01 | 9.79e-02 | 7.72e-01 |
| REACTOME GLUTAMATE AND GLUTAMINE METABOLISM | 13 | 5.41e-01 | 9.78e-02 | 7.72e-01 |
| REACTOME PEPTIDE HORMONE BIOSYNTHESIS | 13 | 5.42e-01 | -9.77e-02 | 7.72e-01 |
| REACTOME NUCLEOTIDE SALVAGE | 21 | 5.42e-01 | 7.69e-02 | 7.72e-01 |
| REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | 18 | 5.42e-01 | 8.30e-02 | 7.72e-01 |
| REACTOME KERATAN SULFATE KERATIN METABOLISM | 34 | 5.42e-01 | -6.04e-02 | 7.72e-01 |
| REACTOME OTHER SEMAPHORIN INTERACTIONS | 18 | 5.43e-01 | -8.27e-02 | 7.72e-01 |
| REACTOME TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE | 10 | 5.44e-01 | -1.11e-01 | 7.72e-01 |
| REACTOME G ALPHA S SIGNALLING EVENTS | 155 | 5.45e-01 | -2.82e-02 | 7.73e-01 |
| REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | 12 | 5.45e-01 | -1.01e-01 | 7.73e-01 |
| REACTOME SIGNALING BY FGFR2 IIIA TM | 19 | 5.47e-01 | 7.98e-02 | 7.74e-01 |
| REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | 15 | 5.48e-01 | 8.97e-02 | 7.74e-01 |
| REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION | 32 | 5.48e-01 | 6.14e-02 | 7.74e-01 |
| REACTOME NEUROTRANSMITTER CLEARANCE | 9 | 5.48e-01 | -1.16e-01 | 7.74e-01 |
| REACTOME EFFECTS OF PIP2 HYDROLYSIS | 26 | 5.48e-01 | -6.80e-02 | 7.74e-01 |
| REACTOME SULFUR AMINO ACID METABOLISM | 27 | 5.51e-01 | 6.64e-02 | 7.76e-01 |
| REACTOME DSCAM INTERACTIONS | 11 | 5.51e-01 | 1.04e-01 | 7.76e-01 |
| REACTOME BASIGIN INTERACTIONS | 24 | 5.51e-01 | 7.02e-02 | 7.76e-01 |
| REACTOME NEUREXINS AND NEUROLIGINS | 51 | 5.51e-01 | -4.82e-02 | 7.76e-01 |
| REACTOME HDL REMODELING | 10 | 5.54e-01 | 1.08e-01 | 7.79e-01 |
| REACTOME CHYLOMICRON CLEARANCE | 5 | 5.57e-01 | -1.52e-01 | 7.82e-01 |
| REACTOME DNA REPLICATION INITIATION | 7 | 5.58e-01 | 1.28e-01 | 7.83e-01 |
| REACTOME SIGNALLING TO P38 VIA RIT AND RIN | 5 | 5.59e-01 | 1.51e-01 | 7.84e-01 |
| REACTOME SIGNAL ATTENUATION | 10 | 5.60e-01 | -1.07e-01 | 7.84e-01 |
| REACTOME INTERLEUKIN 9 SIGNALING | 7 | 5.60e-01 | 1.27e-01 | 7.84e-01 |
| REACTOME ACTIVATION OF BH3 ONLY PROTEINS | 30 | 5.61e-01 | -6.13e-02 | 7.84e-01 |
| REACTOME GRB2 EVENTS IN ERBB2 SIGNALING | 16 | 5.61e-01 | 8.39e-02 | 7.84e-01 |
| REACTOME AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY | 8 | 5.62e-01 | -1.18e-01 | 7.84e-01 |
| REACTOME MIRO GTPASE CYCLE | 8 | 5.62e-01 | 1.18e-01 | 7.84e-01 |
| REACTOME ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY | 10 | 5.63e-01 | -1.06e-01 | 7.84e-01 |
| REACTOME SIALIC ACID METABOLISM | 33 | 5.64e-01 | -5.80e-02 | 7.85e-01 |
| REACTOME PI METABOLISM | 79 | 5.66e-01 | -3.73e-02 | 7.88e-01 |
| REACTOME BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA | 5 | 5.68e-01 | 1.48e-01 | 7.89e-01 |
| REACTOME LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME | 11 | 5.71e-01 | 9.88e-02 | 7.93e-01 |
| REACTOME SYNTHESIS OF 15 EICOSATETRAENOIC ACID DERIVATIVES | 6 | 5.71e-01 | 1.34e-01 | 7.93e-01 |
| REACTOME RAS SIGNALING DOWNSTREAM OF NF1 LOSS OF FUNCTION VARIANTS | 7 | 5.73e-01 | -1.23e-01 | 7.94e-01 |
| REACTOME FORMATION OF XYLULOSE 5 PHOSPHATE | 5 | 5.74e-01 | 1.45e-01 | 7.94e-01 |
| REACTOME APOPTOTIC FACTOR MEDIATED RESPONSE | 19 | 5.74e-01 | 7.45e-02 | 7.94e-01 |
| REACTOME VITAMIN D CALCIFEROL METABOLISM | 12 | 5.75e-01 | -9.36e-02 | 7.94e-01 |
| REACTOME UNWINDING OF DNA | 12 | 5.75e-01 | 9.36e-02 | 7.94e-01 |
| REACTOME REGULATION OF PTEN GENE TRANSCRIPTION | 59 | 5.76e-01 | 4.21e-02 | 7.94e-01 |
| REACTOME SIGNALING BY TGFB FAMILY MEMBERS | 119 | 5.76e-01 | 2.97e-02 | 7.94e-01 |
| REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING | 28 | 5.76e-01 | 6.11e-02 | 7.94e-01 |
| REACTOME RND3 GTPASE CYCLE | 41 | 5.78e-01 | -5.02e-02 | 7.97e-01 |
| REACTOME RUNX3 REGULATES P14 ARF | 10 | 5.80e-01 | -1.01e-01 | 7.98e-01 |
| REACTOME GRB7 EVENTS IN ERBB2 SIGNALING | 5 | 5.82e-01 | 1.42e-01 | 8.01e-01 |
| REACTOME MAP2K AND MAPK ACTIVATION | 38 | 5.83e-01 | -5.15e-02 | 8.01e-01 |
| REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE | 9 | 5.84e-01 | 1.06e-01 | 8.01e-01 |
| REACTOME ER TO GOLGI ANTEROGRADE TRANSPORT | 152 | 5.84e-01 | 2.57e-02 | 8.01e-01 |
| REACTOME PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS | 8 | 5.86e-01 | -1.11e-01 | 8.03e-01 |
| REACTOME AMINE LIGAND BINDING RECEPTORS | 40 | 5.86e-01 | 4.97e-02 | 8.03e-01 |
| REACTOME NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 19 | 5.89e-01 | -7.17e-02 | 8.05e-01 |
| REACTOME RND2 GTPASE CYCLE | 42 | 5.89e-01 | -4.82e-02 | 8.05e-01 |
| REACTOME MTORC1 MEDIATED SIGNALLING | 23 | 5.89e-01 | 6.50e-02 | 8.05e-01 |
| REACTOME SIGNALLING TO ERKS | 34 | 5.90e-01 | -5.35e-02 | 8.05e-01 |
| REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM | 45 | 5.90e-01 | -4.64e-02 | 8.05e-01 |
| REACTOME CYTOCHROME C MEDIATED APOPTOTIC RESPONSE | 12 | 5.92e-01 | 8.95e-02 | 8.06e-01 |
| REACTOME SIGNALING BY NOTCH1 T 7 9 NOTCH1 M1580 K2555 TRANSLOCATION MUTANT | 7 | 5.93e-01 | -1.17e-01 | 8.08e-01 |
| REACTOME ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION | 28 | 5.94e-01 | 5.83e-02 | 8.08e-01 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING | 5 | 5.97e-01 | -1.37e-01 | 8.11e-01 |
| REACTOME IKBA VARIANT LEADS TO EDA ID | 6 | 5.98e-01 | -1.24e-01 | 8.11e-01 |
| REACTOME TERMINAL PATHWAY OF COMPLEMENT | 8 | 5.98e-01 | 1.08e-01 | 8.11e-01 |
| REACTOME SIGNALING BY FGFR IN DISEASE | 62 | 5.98e-01 | -3.87e-02 | 8.11e-01 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS | 9 | 5.99e-01 | -1.01e-01 | 8.12e-01 |
| REACTOME METABOLISM OF AMINE DERIVED HORMONES | 17 | 6.01e-01 | -7.33e-02 | 8.13e-01 |
| REACTOME PENTOSE PHOSPHATE PATHWAY | 12 | 6.02e-01 | 8.69e-02 | 8.14e-01 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE | 5 | 6.02e-01 | -1.35e-01 | 8.14e-01 |
| REACTOME ERYTHROPOIETIN ACTIVATES STAT5 | 7 | 6.03e-01 | 1.14e-01 | 8.14e-01 |
| REACTOME GROWTH HORMONE RECEPTOR SIGNALING | 24 | 6.03e-01 | -6.13e-02 | 8.14e-01 |
| REACTOME OAS ANTIVIRAL RESPONSE | 8 | 6.04e-01 | 1.06e-01 | 8.14e-01 |
| REACTOME SIGNALING BY MAPK MUTANTS | 6 | 6.04e-01 | -1.22e-01 | 8.14e-01 |
| REACTOME RHO GTPASES ACTIVATE IQGAPS | 31 | 6.05e-01 | 5.37e-02 | 8.14e-01 |
| REACTOME SIGNALING BY ERYTHROPOIETIN | 25 | 6.06e-01 | 5.96e-02 | 8.15e-01 |
| REACTOME XENOBIOTICS | 22 | 6.07e-01 | 6.33e-02 | 8.15e-01 |
| REACTOME ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS | 11 | 6.08e-01 | 8.93e-02 | 8.15e-01 |
| REACTOME RUNX3 REGULATES BCL2L11 BIM TRANSCRIPTION | 5 | 6.09e-01 | -1.32e-01 | 8.15e-01 |
| REACTOME RUNX3 REGULATES WNT SIGNALING | 8 | 6.09e-01 | 1.04e-01 | 8.15e-01 |
| REACTOME PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS | 7 | 6.09e-01 | 1.12e-01 | 8.15e-01 |
| REACTOME SUPPRESSION OF APOPTOSIS | 7 | 6.09e-01 | 1.12e-01 | 8.15e-01 |
| REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS | 43 | 6.10e-01 | -4.50e-02 | 8.15e-01 |
| REACTOME SEROTONIN NEUROTRANSMITTER RELEASE CYCLE | 17 | 6.10e-01 | -7.15e-02 | 8.15e-01 |
| REACTOME SARS COV 2 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS | 12 | 6.10e-01 | -8.50e-02 | 8.15e-01 |
| REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | 30 | 6.12e-01 | 5.34e-02 | 8.16e-01 |
| REACTOME PHOSPHORYLATION OF EMI1 | 6 | 6.13e-01 | 1.19e-01 | 8.16e-01 |
| REACTOME MICRORNA MIRNA BIOGENESIS | 25 | 6.13e-01 | 5.84e-02 | 8.16e-01 |
| REACTOME DARPP 32 EVENTS | 24 | 6.13e-01 | 5.96e-02 | 8.16e-01 |
| REACTOME PLATELET SENSITIZATION BY LDL | 17 | 6.13e-01 | 7.08e-02 | 8.16e-01 |
| REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS | 12 | 6.16e-01 | 8.37e-02 | 8.17e-01 |
| REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS | 6 | 6.16e-01 | 1.18e-01 | 8.17e-01 |
| REACTOME SYNTHESIS OF DIPHTHAMIDE EEF2 | 8 | 6.16e-01 | 1.02e-01 | 8.17e-01 |
| REACTOME PI 3K CASCADE FGFR3 | 17 | 6.17e-01 | 7.02e-02 | 8.17e-01 |
| REACTOME FORMATION OF APOPTOSOME | 10 | 6.17e-01 | 9.14e-02 | 8.17e-01 |
| REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS | 27 | 6.19e-01 | 5.54e-02 | 8.18e-01 |
| REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | 11 | 6.19e-01 | 8.65e-02 | 8.19e-01 |
| REACTOME PEPTIDE HORMONE METABOLISM | 84 | 6.20e-01 | 3.13e-02 | 8.19e-01 |
| REACTOME RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS | 5 | 6.21e-01 | -1.28e-01 | 8.19e-01 |
| REACTOME PROLONGED ERK ACTIVATION EVENTS | 14 | 6.21e-01 | -7.62e-02 | 8.19e-01 |
| REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS | 83 | 6.22e-01 | 3.13e-02 | 8.19e-01 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE | 5 | 6.22e-01 | 1.27e-01 | 8.19e-01 |
| REACTOME MAPK1 ERK2 ACTIVATION | 9 | 6.23e-01 | 9.47e-02 | 8.19e-01 |
| REACTOME RUNX2 REGULATES BONE DEVELOPMENT | 29 | 6.24e-01 | 5.26e-02 | 8.20e-01 |
| REACTOME FIBRONECTIN MATRIX FORMATION | 6 | 6.24e-01 | -1.16e-01 | 8.20e-01 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH RAS | 9 | 6.25e-01 | 9.40e-02 | 8.21e-01 |
| REACTOME INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | 28 | 6.26e-01 | 5.33e-02 | 8.21e-01 |
| REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS | 17 | 6.27e-01 | -6.81e-02 | 8.21e-01 |
| REACTOME ERYTHROPOIETIN ACTIVATES RAS | 14 | 6.27e-01 | 7.49e-02 | 8.21e-01 |
| REACTOME TACHYKININ RECEPTORS BIND TACHYKININS | 5 | 6.28e-01 | -1.25e-01 | 8.21e-01 |
| REACTOME TRNA MODIFICATION IN THE MITOCHONDRION | 8 | 6.28e-01 | 9.89e-02 | 8.21e-01 |
| REACTOME MISMATCH REPAIR | 15 | 6.29e-01 | 7.21e-02 | 8.22e-01 |
| REACTOME LTC4 CYSLTR MEDIATED IL4 PRODUCTION | 6 | 6.29e-01 | -1.14e-01 | 8.22e-01 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING | 5 | 6.33e-01 | -1.23e-01 | 8.25e-01 |
| REACTOME AMINO ACIDS REGULATE MTORC1 | 53 | 6.34e-01 | 3.78e-02 | 8.25e-01 |
| REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | 14 | 6.35e-01 | 7.33e-02 | 8.25e-01 |
| REACTOME SPHINGOLIPID METABOLISM | 84 | 6.35e-01 | -3.00e-02 | 8.25e-01 |
| REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING | 30 | 6.35e-01 | 5.00e-02 | 8.25e-01 |
| REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | 7 | 6.35e-01 | -1.03e-01 | 8.25e-01 |
| REACTOME RHOH GTPASE CYCLE | 37 | 6.37e-01 | 4.48e-02 | 8.25e-01 |
| REACTOME BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA | 5 | 6.37e-01 | 1.22e-01 | 8.25e-01 |
| REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | 14 | 6.37e-01 | 7.28e-02 | 8.25e-01 |
| REACTOME MYOGENESIS | 29 | 6.37e-01 | 5.06e-02 | 8.25e-01 |
| REACTOME EARLY SARS COV 2 INFECTION EVENTS | 34 | 6.42e-01 | -4.61e-02 | 8.31e-01 |
| REACTOME APEX1 INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | 7 | 6.44e-01 | 1.01e-01 | 8.33e-01 |
| REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING | 6 | 6.46e-01 | 1.08e-01 | 8.35e-01 |
| REACTOME SIGNALING BY FLT3 FUSION PROTEINS | 19 | 6.47e-01 | -6.07e-02 | 8.35e-01 |
| REACTOME GPER1 SIGNALING | 45 | 6.47e-01 | -3.94e-02 | 8.35e-01 |
| REACTOME NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10 | 12 | 6.49e-01 | -7.59e-02 | 8.36e-01 |
| REACTOME REGULATION OF LIPID METABOLISM BY PPARALPHA | 115 | 6.49e-01 | 2.46e-02 | 8.36e-01 |
| REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | 17 | 6.50e-01 | 6.35e-02 | 8.37e-01 |
| REACTOME SCAVENGING BY CLASS A RECEPTORS | 19 | 6.52e-01 | 5.98e-02 | 8.37e-01 |
| REACTOME CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION | 11 | 6.52e-01 | -7.85e-02 | 8.37e-01 |
| REACTOME IRS MEDIATED SIGNALLING | 47 | 6.52e-01 | -3.80e-02 | 8.37e-01 |
| REACTOME HSF1 DEPENDENT TRANSACTIVATION | 37 | 6.54e-01 | 4.26e-02 | 8.39e-01 |
| REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF | 17 | 6.54e-01 | 6.27e-02 | 8.39e-01 |
| REACTOME REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM | 11 | 6.57e-01 | -7.74e-02 | 8.41e-01 |
| REACTOME ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING | 23 | 6.57e-01 | 5.34e-02 | 8.41e-01 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS | 5 | 6.59e-01 | 1.14e-01 | 8.43e-01 |
| REACTOME SUMO IS CONJUGATED TO E1 UBA2 SAE1 | 5 | 6.60e-01 | -1.14e-01 | 8.43e-01 |
| REACTOME ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS | 41 | 6.61e-01 | 3.96e-02 | 8.44e-01 |
| REACTOME BETA CATENIN PHOSPHORYLATION CASCADE | 16 | 6.61e-01 | 6.33e-02 | 8.44e-01 |
| REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2 | 17 | 6.62e-01 | -6.12e-02 | 8.44e-01 |
| REACTOME TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX | 14 | 6.64e-01 | 6.70e-02 | 8.46e-01 |
| REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR4 | 14 | 6.65e-01 | -6.68e-02 | 8.46e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE | 20 | 6.66e-01 | 5.58e-02 | 8.46e-01 |
| REACTOME TRANSPORT OF ORGANIC ANIONS | 10 | 6.66e-01 | -7.87e-02 | 8.46e-01 |
| REACTOME O LINKED GLYCOSYLATION OF MUCINS | 61 | 6.66e-01 | -3.19e-02 | 8.46e-01 |
| REACTOME NEUROFASCIN INTERACTIONS | 6 | 6.68e-01 | 1.01e-01 | 8.47e-01 |
| REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | 76 | 6.69e-01 | -2.84e-02 | 8.48e-01 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3 | 11 | 6.69e-01 | 7.44e-02 | 8.48e-01 |
| REACTOME RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA | 7 | 6.70e-01 | 9.30e-02 | 8.48e-01 |
| REACTOME MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS | 17 | 6.70e-01 | 5.96e-02 | 8.48e-01 |
| REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS | 20 | 6.72e-01 | 5.47e-02 | 8.49e-01 |
| REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN | 37 | 6.74e-01 | -4.00e-02 | 8.50e-01 |
| REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING | 33 | 6.74e-01 | 4.23e-02 | 8.50e-01 |
| REACTOME FGFR2C LIGAND BINDING AND ACTIVATION | 12 | 6.76e-01 | -6.97e-02 | 8.52e-01 |
| REACTOME SCAVENGING BY CLASS B RECEPTORS | 6 | 6.77e-01 | -9.81e-02 | 8.53e-01 |
| REACTOME PREDNISONE ADME | 10 | 6.78e-01 | 7.58e-02 | 8.53e-01 |
| REACTOME INSULIN RECEPTOR RECYCLING | 29 | 6.79e-01 | 4.44e-02 | 8.53e-01 |
| REACTOME INTERLEUKIN 2 FAMILY SIGNALING | 40 | 6.79e-01 | 3.78e-02 | 8.53e-01 |
| REACTOME NETRIN MEDIATED REPULSION SIGNALS | 8 | 6.80e-01 | -8.43e-02 | 8.53e-01 |
| REACTOME HDL CLEARANCE | 5 | 6.80e-01 | -1.07e-01 | 8.53e-01 |
| REACTOME SYNTHESIS OF UDP N ACETYL GLUCOSAMINE | 7 | 6.81e-01 | 8.98e-02 | 8.53e-01 |
| REACTOME COBALAMIN CBL METABOLISM | 7 | 6.82e-01 | 8.94e-02 | 8.53e-01 |
| REACTOME ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT | 23 | 6.82e-01 | 4.93e-02 | 8.53e-01 |
| REACTOME RHO GTPASES ACTIVATE ROCKS | 19 | 6.83e-01 | -5.42e-02 | 8.53e-01 |
| REACTOME CD163 MEDIATING AN ANTI INFLAMMATORY RESPONSE | 9 | 6.83e-01 | -7.87e-02 | 8.53e-01 |
| REACTOME ROBO RECEPTORS BIND AKAP5 | 9 | 6.83e-01 | -7.87e-02 | 8.53e-01 |
| REACTOME PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING | 5 | 6.83e-01 | 1.05e-01 | 8.53e-01 |
| REACTOME METABOLISM OF CARBOHYDRATES | 279 | 6.84e-01 | -1.42e-02 | 8.53e-01 |
| REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | 45 | 6.84e-01 | -3.50e-02 | 8.53e-01 |
| REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | 29 | 6.85e-01 | 4.35e-02 | 8.53e-01 |
| REACTOME INTERFERON GAMMA SIGNALING | 88 | 6.86e-01 | 2.49e-02 | 8.53e-01 |
| REACTOME VLDL CLEARANCE | 6 | 6.87e-01 | -9.51e-02 | 8.53e-01 |
| REACTOME INTERLEUKIN 6 FAMILY SIGNALING | 24 | 6.87e-01 | 4.75e-02 | 8.53e-01 |
| REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION | 250 | 6.87e-01 | -1.48e-02 | 8.53e-01 |
| REACTOME CREATINE METABOLISM | 9 | 6.87e-01 | -7.75e-02 | 8.53e-01 |
| REACTOME MOLYBDENUM COFACTOR BIOSYNTHESIS | 6 | 6.88e-01 | 9.47e-02 | 8.53e-01 |
| REACTOME CYP2E1 REACTIONS | 10 | 6.88e-01 | 7.33e-02 | 8.53e-01 |
| REACTOME MASTL FACILITATES MITOTIC PROGRESSION | 10 | 6.91e-01 | 7.25e-02 | 8.56e-01 |
| REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | 21 | 6.91e-01 | -5.00e-02 | 8.56e-01 |
| REACTOME REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR | 11 | 6.92e-01 | 6.90e-02 | 8.56e-01 |
| REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | 13 | 6.93e-01 | 6.32e-02 | 8.56e-01 |
| REACTOME RND1 GTPASE CYCLE | 41 | 6.94e-01 | 3.55e-02 | 8.56e-01 |
| REACTOME TRIGLYCERIDE BIOSYNTHESIS | 12 | 6.95e-01 | -6.54e-02 | 8.56e-01 |
| REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | 63 | 6.96e-01 | 2.85e-02 | 8.56e-01 |
| REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | 15 | 6.96e-01 | -5.83e-02 | 8.56e-01 |
| REACTOME PI 3K CASCADE FGFR4 | 19 | 6.96e-01 | 5.18e-02 | 8.56e-01 |
| REACTOME MET RECEPTOR ACTIVATION | 6 | 6.97e-01 | -9.19e-02 | 8.56e-01 |
| REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL | 15 | 6.97e-01 | -5.81e-02 | 8.56e-01 |
| REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | 16 | 6.97e-01 | -5.62e-02 | 8.56e-01 |
| REACTOME CTLA4 INHIBITORY SIGNALING | 21 | 6.98e-01 | 4.89e-02 | 8.56e-01 |
| REACTOME RHO GTPASES ACTIVATE CIT | 19 | 6.98e-01 | 5.14e-02 | 8.56e-01 |
| REACTOME PROPIONYL COA CATABOLISM | 5 | 7.00e-01 | -9.96e-02 | 8.57e-01 |
| REACTOME COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC | 52 | 7.00e-01 | 3.09e-02 | 8.57e-01 |
| REACTOME THYROXINE BIOSYNTHESIS | 10 | 7.00e-01 | -7.03e-02 | 8.57e-01 |
| REACTOME SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS | 12 | 7.05e-01 | -6.32e-02 | 8.61e-01 |
| REACTOME ACTIVATION OF NIMA KINASES NEK9 NEK6 NEK7 | 7 | 7.05e-01 | 8.27e-02 | 8.61e-01 |
| REACTOME RHOF GTPASE CYCLE | 40 | 7.05e-01 | 3.46e-02 | 8.61e-01 |
| REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | 51 | 7.07e-01 | 3.04e-02 | 8.63e-01 |
| REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING | 30 | 7.10e-01 | 3.93e-02 | 8.65e-01 |
| REACTOME HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS | 7 | 7.11e-01 | -8.09e-02 | 8.66e-01 |
| REACTOME RECYCLING PATHWAY OF L1 | 43 | 7.11e-01 | 3.26e-02 | 8.66e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST | 14 | 7.12e-01 | 5.69e-02 | 8.66e-01 |
| REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | 17 | 7.14e-01 | 5.14e-02 | 8.67e-01 |
| REACTOME POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION | 27 | 7.15e-01 | 4.07e-02 | 8.67e-01 |
| REACTOME SIGNALING BY LEPTIN | 11 | 7.15e-01 | -6.36e-02 | 8.67e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS | 36 | 7.16e-01 | 3.51e-02 | 8.68e-01 |
| REACTOME LDL CLEARANCE | 19 | 7.17e-01 | -4.80e-02 | 8.68e-01 |
| REACTOME METABOLISM OF VITAMINS AND COFACTORS | 185 | 7.17e-01 | -1.54e-02 | 8.68e-01 |
| REACTOME REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA | 15 | 7.19e-01 | -5.37e-02 | 8.69e-01 |
| REACTOME GPCR LIGAND BINDING | 444 | 7.19e-01 | 9.94e-03 | 8.70e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS | 12 | 7.22e-01 | 5.94e-02 | 8.72e-01 |
| REACTOME NRCAM INTERACTIONS | 6 | 7.22e-01 | -8.39e-02 | 8.72e-01 |
| REACTOME DEFECTIVE RIPK1 MEDIATED REGULATED NECROSIS | 7 | 7.23e-01 | 7.74e-02 | 8.72e-01 |
| REACTOME SIGNALING BY HIPPO | 19 | 7.23e-01 | -4.69e-02 | 8.72e-01 |
| REACTOME ESTROGEN BIOSYNTHESIS | 6 | 7.24e-01 | -8.33e-02 | 8.72e-01 |
| REACTOME SIGNALING BY WNT IN CANCER | 32 | 7.25e-01 | 3.59e-02 | 8.72e-01 |
| REACTOME DEX H BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION | 7 | 7.26e-01 | 7.66e-02 | 8.72e-01 |
| REACTOME GLYCOLYSIS | 70 | 7.26e-01 | -2.43e-02 | 8.72e-01 |
| REACTOMEMATURATION OF SARS COV 1 NUCLEOPROTEIN | 11 | 7.27e-01 | -6.09e-02 | 8.72e-01 |
| REACTOME SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS | 74 | 7.27e-01 | 2.35e-02 | 8.72e-01 |
| REACTOME TIE2 SIGNALING | 18 | 7.27e-01 | 4.75e-02 | 8.72e-01 |
| REACTOME SIGNALING BY FLT3 ITD AND TKD MUTANTS | 16 | 7.28e-01 | 5.01e-02 | 8.73e-01 |
| REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES | 21 | 7.29e-01 | 4.36e-02 | 8.73e-01 |
| REACTOME SYNTHESIS OF 12 EICOSATETRAENOIC ACID DERIVATIVES | 7 | 7.30e-01 | -7.52e-02 | 8.74e-01 |
| REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES | 29 | 7.31e-01 | 3.69e-02 | 8.74e-01 |
| REACTOME GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION | 7 | 7.32e-01 | -7.46e-02 | 8.74e-01 |
| REACTOME FCGR3A MEDIATED IL10 SYNTHESIS | 36 | 7.33e-01 | -3.29e-02 | 8.74e-01 |
| REACTOME ENDOGENOUS STEROLS | 26 | 7.34e-01 | 3.85e-02 | 8.74e-01 |
| REACTOME PLATELET HOMEOSTASIS | 85 | 7.34e-01 | -2.13e-02 | 8.74e-01 |
| REACTOME NFE2L2 REGULATING ANTI OXIDANT DETOXIFICATION ENZYMES | 17 | 7.34e-01 | 4.76e-02 | 8.74e-01 |
| REACTOME CHYLOMICRON ASSEMBLY | 10 | 7.34e-01 | -6.20e-02 | 8.74e-01 |
| REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION | 42 | 7.35e-01 | -3.02e-02 | 8.74e-01 |
| REACTOME AQUAPORIN MEDIATED TRANSPORT | 51 | 7.35e-01 | -2.74e-02 | 8.74e-01 |
| REACTOME CA2 PATHWAY | 62 | 7.38e-01 | -2.46e-02 | 8.77e-01 |
| REACTOME BILE ACID AND BILE SALT METABOLISM | 45 | 7.38e-01 | 2.88e-02 | 8.77e-01 |
| REACTOME KILLING MECHANISMS | 11 | 7.39e-01 | 5.80e-02 | 8.77e-01 |
| REACTOME MINERALOCORTICOID BIOSYNTHESIS | 6 | 7.40e-01 | 7.83e-02 | 8.77e-01 |
| REACTOME BINDING OF TCF LEF CTNNB1 TO TARGET GENE PROMOTERS | 8 | 7.41e-01 | 6.75e-02 | 8.78e-01 |
| REACTOME DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE | 30 | 7.42e-01 | 3.48e-02 | 8.78e-01 |
| REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | 9 | 7.43e-01 | 6.32e-02 | 8.78e-01 |
| REACTOME PROTON COUPLED MONOCARBOXYLATE TRANSPORT | 6 | 7.43e-01 | -7.72e-02 | 8.79e-01 |
| REACTOME LRR FLII INTERACTING PROTEIN 1 LRRFIP1 ACTIVATES TYPE I IFN PRODUCTION | 5 | 7.44e-01 | -8.42e-02 | 8.79e-01 |
| REACTOME PROCESSING OF SMDT1 | 16 | 7.45e-01 | -4.70e-02 | 8.79e-01 |
| REACTOME PI 3K CASCADE FGFR2 | 22 | 7.45e-01 | 4.00e-02 | 8.79e-01 |
| REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES | 34 | 7.49e-01 | 3.17e-02 | 8.83e-01 |
| REACTOME IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS | 17 | 7.51e-01 | -4.45e-02 | 8.84e-01 |
| REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | 11 | 7.51e-01 | -5.52e-02 | 8.84e-01 |
| REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET | 8 | 7.51e-01 | 6.47e-02 | 8.84e-01 |
| REACTOME UPTAKE AND ACTIONS OF BACTERIAL TOXINS | 28 | 7.52e-01 | 3.45e-02 | 8.84e-01 |
| REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | 29 | 7.53e-01 | -3.37e-02 | 8.85e-01 |
| REACTOME FGFR3 LIGAND BINDING AND ACTIVATION | 12 | 7.54e-01 | -5.22e-02 | 8.85e-01 |
| REACTOME SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA PHE | 6 | 7.55e-01 | -7.35e-02 | 8.85e-01 |
| REACTOME PKMTS METHYLATE HISTONE LYSINES | 64 | 7.55e-01 | 2.25e-02 | 8.85e-01 |
| REACTOME RHOBTB1 GTPASE CYCLE | 22 | 7.56e-01 | 3.83e-02 | 8.85e-01 |
| REACTOME NEGATIVE REGULATION OF ACTIVITY OF TFAP2 AP 2 FAMILY TRANSCRIPTION FACTORS | 10 | 7.56e-01 | -5.67e-02 | 8.85e-01 |
| REACTOME INSULIN PROCESSING | 24 | 7.58e-01 | 3.63e-02 | 8.86e-01 |
| REACTOME REGULATION OF NPAS4 GENE EXPRESSION | 13 | 7.58e-01 | 4.93e-02 | 8.86e-01 |
| REACTOME METABOLISM OF PORPHYRINS | 26 | 7.58e-01 | 3.48e-02 | 8.86e-01 |
| REACTOME SIGNALING BY NOTCH3 | 48 | 7.59e-01 | 2.56e-02 | 8.86e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION BY VENTX | 41 | 7.62e-01 | 2.74e-02 | 8.88e-01 |
| REACTOME SYNTHESIS OF LIPOXINS LX | 6 | 7.62e-01 | 7.14e-02 | 8.88e-01 |
| REACTOME STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES | 16 | 7.64e-01 | -4.33e-02 | 8.89e-01 |
| REACTOME NEPHRIN FAMILY INTERACTIONS | 22 | 7.65e-01 | -3.69e-02 | 8.89e-01 |
| REACTOME PTK6 PROMOTES HIF1A STABILIZATION | 6 | 7.65e-01 | 7.06e-02 | 8.89e-01 |
| REACTOME PASSIVE TRANSPORT BY AQUAPORINS | 13 | 7.65e-01 | -4.78e-02 | 8.89e-01 |
| REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | 20 | 7.66e-01 | 3.84e-02 | 8.90e-01 |
| REACTOME DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM | 38 | 7.68e-01 | -2.76e-02 | 8.91e-01 |
| REACTOME FGFR1C LIGAND BINDING AND ACTIVATION | 11 | 7.69e-01 | -5.11e-02 | 8.91e-01 |
| REACTOME SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS | 16 | 7.69e-01 | -4.24e-02 | 8.91e-01 |
| REACTOME SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER | 15 | 7.72e-01 | 4.32e-02 | 8.94e-01 |
| REACTOME HYALURONAN BIOSYNTHESIS AND EXPORT | 5 | 7.74e-01 | 7.41e-02 | 8.96e-01 |
| REACTOME OVARIAN TUMOR DOMAIN PROTEASES | 36 | 7.75e-01 | -2.75e-02 | 8.96e-01 |
| REACTOME PROTEIN REPAIR | 6 | 7.75e-01 | 6.73e-02 | 8.96e-01 |
| REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION | 74 | 7.78e-01 | -1.90e-02 | 8.98e-01 |
| REACTOME PI5P REGULATES TP53 ACETYLATION | 9 | 7.79e-01 | 5.40e-02 | 8.99e-01 |
| REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | 19 | 7.80e-01 | 3.71e-02 | 8.99e-01 |
| REACTOME G ALPHA I SIGNALLING EVENTS | 304 | 7.81e-01 | 9.27e-03 | 9.00e-01 |
| REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2 | 13 | 7.82e-01 | 4.44e-02 | 9.00e-01 |
| REACTOME GAP JUNCTION DEGRADATION | 12 | 7.83e-01 | 4.60e-02 | 9.00e-01 |
| REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS | 18 | 7.83e-01 | 3.75e-02 | 9.00e-01 |
| REACTOME SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION | 8 | 7.85e-01 | -5.58e-02 | 9.02e-01 |
| REACTOME CD28 DEPENDENT PI3K AKT SIGNALING | 22 | 7.86e-01 | -3.35e-02 | 9.02e-01 |
| REACTOME SODIUM CALCIUM EXCHANGERS | 11 | 7.86e-01 | -4.72e-02 | 9.02e-01 |
| REACTOME GABA RECEPTOR ACTIVATION | 57 | 7.87e-01 | 2.07e-02 | 9.02e-01 |
| REACTOME EPH EPHRIN MEDIATED REPULSION OF CELLS | 50 | 7.88e-01 | 2.20e-02 | 9.03e-01 |
| REACTOME SUMOYLATION OF RNA BINDING PROTEINS | 47 | 7.92e-01 | 2.23e-02 | 9.06e-01 |
| REACTOME SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL | 8 | 7.92e-01 | -5.38e-02 | 9.07e-01 |
| REACTOME SUMOYLATION OF DNA REPLICATION PROTEINS | 46 | 7.93e-01 | 2.24e-02 | 9.07e-01 |
| REACTOME SIGNALING BY FGFR3 | 39 | 7.94e-01 | 2.42e-02 | 9.07e-01 |
| REACTOME GABA B RECEPTOR ACTIVATION | 43 | 7.94e-01 | -2.30e-02 | 9.07e-01 |
| REACTOME GLYCOSPHINGOLIPID METABOLISM | 39 | 7.95e-01 | -2.40e-02 | 9.08e-01 |
| REACTOME NEGATIVE REGULATION OF MAPK PATHWAY | 41 | 7.97e-01 | -2.32e-02 | 9.09e-01 |
| REACTOME FGFR1 LIGAND BINDING AND ACTIVATION | 15 | 7.98e-01 | 3.81e-02 | 9.09e-01 |
| REACTOME SIGNALING BY RNF43 MUTANTS | 8 | 7.98e-01 | -5.22e-02 | 9.09e-01 |
| REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | 19 | 7.98e-01 | -3.38e-02 | 9.09e-01 |
| REACTOME UREA CYCLE | 9 | 8.00e-01 | 4.89e-02 | 9.09e-01 |
| REACTOME UPTAKE OF DIETARY COBALAMINS INTO ENTEROCYTES | 9 | 8.00e-01 | -4.88e-02 | 9.09e-01 |
| REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | 24 | 8.03e-01 | 2.94e-02 | 9.12e-01 |
| REACTOME PHASE II CONJUGATION OF COMPOUNDS | 102 | 8.03e-01 | 1.43e-02 | 9.12e-01 |
| REACTOME TIGHT JUNCTION INTERACTIONS | 29 | 8.05e-01 | -2.65e-02 | 9.12e-01 |
| REACTOME CHOLINE CATABOLISM | 6 | 8.05e-01 | -5.82e-02 | 9.12e-01 |
| REACTOME PHASE 1 INACTIVATION OF FAST NA CHANNELS | 6 | 8.06e-01 | -5.79e-02 | 9.13e-01 |
| REACTOME PTK6 EXPRESSION | 5 | 8.09e-01 | -6.23e-02 | 9.16e-01 |
| REACTOME SUMO IS TRANSFERRED FROM E1 TO E2 UBE2I UBC9 | 7 | 8.10e-01 | -5.24e-02 | 9.16e-01 |
| REACTOME INTRAFLAGELLAR TRANSPORT | 50 | 8.11e-01 | 1.96e-02 | 9.16e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST | 18 | 8.13e-01 | 3.23e-02 | 9.17e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES | 12 | 8.13e-01 | -3.95e-02 | 9.17e-01 |
| REACTOME POST TRANSCRIPTIONAL SILENCING BY SMALL RNAS | 7 | 8.13e-01 | -5.16e-02 | 9.17e-01 |
| REACTOME GLUCOCORTICOID BIOSYNTHESIS | 10 | 8.13e-01 | 4.31e-02 | 9.17e-01 |
| REACTOME NGF INDEPENDANT TRKA ACTIVATION | 5 | 8.15e-01 | 6.04e-02 | 9.18e-01 |
| REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS | 15 | 8.16e-01 | -3.46e-02 | 9.19e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN | 13 | 8.17e-01 | 3.71e-02 | 9.19e-01 |
| REACTOME PHASE 3 RAPID REPOLARISATION | 8 | 8.18e-01 | -4.69e-02 | 9.20e-01 |
| REACTOME RUNX3 REGULATES NOTCH SIGNALING | 13 | 8.19e-01 | 3.67e-02 | 9.20e-01 |
| REACTOME PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS | 21 | 8.21e-01 | 2.85e-02 | 9.21e-01 |
| REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS | 81 | 8.22e-01 | 1.45e-02 | 9.21e-01 |
| REACTOME RRNA MODIFICATION IN THE MITOCHONDRION | 6 | 8.22e-01 | -5.31e-02 | 9.21e-01 |
| REACTOME SIGNALING BY PDGFR IN DISEASE | 20 | 8.23e-01 | 2.89e-02 | 9.21e-01 |
| REACTOME LIPID PARTICLE ORGANIZATION | 6 | 8.23e-01 | 5.26e-02 | 9.21e-01 |
| REACTOME METHIONINE SALVAGE PATHWAY | 6 | 8.24e-01 | 5.25e-02 | 9.21e-01 |
| REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | 160 | 8.25e-01 | 1.01e-02 | 9.22e-01 |
| REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | 16 | 8.30e-01 | 3.09e-02 | 9.28e-01 |
| REACTOME GAP JUNCTION ASSEMBLY | 36 | 8.34e-01 | 2.01e-02 | 9.31e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4 | 33 | 8.35e-01 | 2.09e-02 | 9.31e-01 |
| REACTOME SIGNALING BY FGFR1 | 49 | 8.35e-01 | 1.72e-02 | 9.31e-01 |
| REACTOME MATURATION OF SARS COV 2 NUCLEOPROTEIN | 15 | 8.36e-01 | -3.09e-02 | 9.31e-01 |
| REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE | 11 | 8.36e-01 | -3.60e-02 | 9.31e-01 |
| REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS | 21 | 8.38e-01 | -2.58e-02 | 9.32e-01 |
| REACTOME SHC1 EVENTS IN EGFR SIGNALING | 14 | 8.39e-01 | 3.14e-02 | 9.32e-01 |
| REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES | 7 | 8.39e-01 | -4.42e-02 | 9.33e-01 |
| REACTOME ABACAVIR TRANSMEMBRANE TRANSPORT | 5 | 8.41e-01 | 5.18e-02 | 9.33e-01 |
| REACTOME LIPOPHAGY | 9 | 8.42e-01 | -3.85e-02 | 9.33e-01 |
| REACTOME LGI ADAM INTERACTIONS | 14 | 8.42e-01 | 3.08e-02 | 9.33e-01 |
| REACTOME P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1 | 6 | 8.42e-01 | 4.69e-02 | 9.33e-01 |
| REACTOME FGFR2 LIGAND BINDING AND ACTIVATION | 19 | 8.42e-01 | 2.64e-02 | 9.33e-01 |
| REACTOME COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC | 98 | 8.43e-01 | 1.16e-02 | 9.33e-01 |
| REACTOME VITAMIN B1 THIAMIN METABOLISM | 5 | 8.45e-01 | 5.05e-02 | 9.34e-01 |
| REACTOME ACTIVATION OF RAC1 | 12 | 8.46e-01 | -3.24e-02 | 9.35e-01 |
| REACTOME CARGO CONCENTRATION IN THE ER | 32 | 8.47e-01 | -1.97e-02 | 9.35e-01 |
| REACTOME REGULATION OF MECP2 EXPRESSION AND ACTIVITY | 30 | 8.48e-01 | -2.03e-02 | 9.35e-01 |
| REACTOME INTEGRIN SIGNALING | 27 | 8.48e-01 | -2.13e-02 | 9.35e-01 |
| REACTOME SCAVENGING BY CLASS F RECEPTORS | 6 | 8.49e-01 | -4.48e-02 | 9.36e-01 |
| REACTOME NADE MODULATES DEATH SIGNALLING | 5 | 8.50e-01 | -4.89e-02 | 9.36e-01 |
| REACTOME CALCINEURIN ACTIVATES NFAT | 9 | 8.50e-01 | 3.64e-02 | 9.36e-01 |
| REACTOME CD28 CO STIMULATION | 32 | 8.51e-01 | 1.91e-02 | 9.36e-01 |
| REACTOME NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 24 | 8.52e-01 | 2.20e-02 | 9.36e-01 |
| REACTOME SIGNALING BY FGFR4 | 40 | 8.52e-01 | 1.70e-02 | 9.36e-01 |
| REACTOME COPII MEDIATED VESICLE TRANSPORT | 66 | 8.53e-01 | 1.32e-02 | 9.36e-01 |
| REACTOME REGULATION OF RUNX1 EXPRESSION AND ACTIVITY | 17 | 8.54e-01 | -2.57e-02 | 9.37e-01 |
| REACTOME OPIOID SIGNALLING | 89 | 8.55e-01 | 1.12e-02 | 9.37e-01 |
| REACTOME GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | 34 | 8.58e-01 | -1.78e-02 | 9.39e-01 |
| REACTOME ERK MAPK TARGETS | 20 | 8.58e-01 | -2.31e-02 | 9.39e-01 |
| REACTOME IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN | 5 | 8.60e-01 | -4.56e-02 | 9.41e-01 |
| REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR2 | 29 | 8.61e-01 | -1.88e-02 | 9.41e-01 |
| REACTOME REGULATION OF PTEN MRNA TRANSLATION | 9 | 8.62e-01 | -3.34e-02 | 9.41e-01 |
| REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | 14 | 8.62e-01 | -2.68e-02 | 9.41e-01 |
| REACTOME SUMOYLATION OF UBIQUITINYLATION PROTEINS | 39 | 8.62e-01 | 1.60e-02 | 9.41e-01 |
| REACTOME RHOD GTPASE CYCLE | 49 | 8.63e-01 | -1.42e-02 | 9.41e-01 |
| REACTOME CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND | 9 | 8.65e-01 | -3.28e-02 | 9.42e-01 |
| REACTOME GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION | 42 | 8.65e-01 | 1.51e-02 | 9.42e-01 |
| REACTOME PYRIMIDINE SALVAGE | 10 | 8.66e-01 | -3.09e-02 | 9.42e-01 |
| REACTOME UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION | 19 | 8.67e-01 | -2.22e-02 | 9.43e-01 |
| REACTOME ARMS MEDIATED ACTIVATION | 7 | 8.69e-01 | 3.59e-02 | 9.45e-01 |
| REACTOME GLUCONEOGENESIS | 33 | 8.70e-01 | 1.64e-02 | 9.45e-01 |
| REACTOME EPHB MEDIATED FORWARD SIGNALING | 41 | 8.71e-01 | 1.46e-02 | 9.45e-01 |
| REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | 32 | 8.72e-01 | 1.65e-02 | 9.45e-01 |
| REACTOME SYNTHESIS OF PE | 13 | 8.73e-01 | 2.56e-02 | 9.45e-01 |
| REACTOME NICOTINATE METABOLISM | 31 | 8.73e-01 | -1.66e-02 | 9.45e-01 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FYN | 7 | 8.73e-01 | 3.48e-02 | 9.45e-01 |
| REACTOME SIGNALING BY FGFR2 IN DISEASE | 42 | 8.74e-01 | 1.42e-02 | 9.45e-01 |
| REACTOME GLUCAGON TYPE LIGAND RECEPTORS | 32 | 8.75e-01 | 1.60e-02 | 9.46e-01 |
| REACTOME AZATHIOPRINE ADME | 22 | 8.76e-01 | 1.93e-02 | 9.46e-01 |
| REACTOME GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION | 14 | 8.78e-01 | 2.38e-02 | 9.47e-01 |
| REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR4 | 26 | 8.81e-01 | -1.69e-02 | 9.51e-01 |
| REACTOME PP2A MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS | 6 | 8.83e-01 | 3.48e-02 | 9.51e-01 |
| REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | 23 | 8.83e-01 | 1.77e-02 | 9.51e-01 |
| REACTOME REGULATION OF NF KAPPA B SIGNALING | 17 | 8.84e-01 | 2.05e-02 | 9.51e-01 |
| REACTOME EPHA MEDIATED GROWTH CONE COLLAPSE | 29 | 8.84e-01 | -1.56e-02 | 9.51e-01 |
| REACTOME BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA | 5 | 8.85e-01 | -3.75e-02 | 9.51e-01 |
| REACTOME POTENTIAL THERAPEUTICS FOR SARS | 92 | 8.86e-01 | 8.63e-03 | 9.52e-01 |
| REACTOME ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA | 5 | 8.87e-01 | -3.67e-02 | 9.52e-01 |
| REACTOME TNF SIGNALING | 54 | 8.88e-01 | -1.11e-02 | 9.52e-01 |
| REACTOME BIOLOGICAL OXIDATIONS | 210 | 8.89e-01 | 5.57e-03 | 9.54e-01 |
| REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | 36 | 8.94e-01 | 1.28e-02 | 9.58e-01 |
| REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS | 101 | 8.94e-01 | -7.65e-03 | 9.58e-01 |
| REACTOME VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS | 42 | 8.95e-01 | -1.18e-02 | 9.58e-01 |
| REACTOME FRS MEDIATED FGFR1 SIGNALING | 23 | 8.97e-01 | -1.56e-02 | 9.59e-01 |
| REACTOME RELEASE OF HH NP FROM THE SECRETING CELL | 8 | 8.97e-01 | -2.64e-02 | 9.59e-01 |
| REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | 11 | 8.98e-01 | 2.24e-02 | 9.59e-01 |
| REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | 54 | 8.99e-01 | -9.94e-03 | 9.60e-01 |
| REACTOME SHC MEDIATED CASCADE FGFR1 | 21 | 9.01e-01 | -1.58e-02 | 9.61e-01 |
| REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX | 36 | 9.01e-01 | 1.19e-02 | 9.61e-01 |
| REACTOME TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS | 26 | 9.10e-01 | 1.28e-02 | 9.68e-01 |
| REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI | 26 | 9.10e-01 | -1.28e-02 | 9.68e-01 |
| REACTOME FATTY ACIDS | 15 | 9.10e-01 | -1.69e-02 | 9.68e-01 |
| REACTOME REGULATION OF NPAS4 MRNA TRANSLATION | 9 | 9.11e-01 | 2.16e-02 | 9.68e-01 |
| REACTOME NICOTINAMIDE SALVAGING | 19 | 9.12e-01 | 1.47e-02 | 9.69e-01 |
| REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | 15 | 9.12e-01 | 1.65e-02 | 9.69e-01 |
| REACTOME CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN | 45 | 9.13e-01 | 9.45e-03 | 9.69e-01 |
| REACTOME VLDL ASSEMBLY | 5 | 9.17e-01 | -2.70e-02 | 9.72e-01 |
| REACTOME SIGNALING BY INSULIN RECEPTOR | 80 | 9.17e-01 | -6.73e-03 | 9.72e-01 |
| REACTOME NEF MEDIATED CD8 DOWN REGULATION | 7 | 9.18e-01 | -2.24e-02 | 9.72e-01 |
| REACTOME RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS | 9 | 9.19e-01 | 1.96e-02 | 9.72e-01 |
| REACTOME TRANSPORT OF RCBL WITHIN THE BODY | 8 | 9.19e-01 | -2.07e-02 | 9.72e-01 |
| REACTOME BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA | 6 | 9.20e-01 | 2.38e-02 | 9.72e-01 |
| REACTOME INWARDLY RECTIFYING K CHANNELS | 35 | 9.21e-01 | -9.74e-03 | 9.73e-01 |
| REACTOME DEFECTS IN BIOTIN BTN METABOLISM | 8 | 9.21e-01 | 2.02e-02 | 9.73e-01 |
| REACTOME CONSTITUTIVE SIGNALING BY EGFRVIII | 15 | 9.22e-01 | 1.46e-02 | 9.73e-01 |
| REACTOME ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA | 15 | 9.23e-01 | -1.44e-02 | 9.73e-01 |
| REACTOME CIPROFLOXACIN ADME | 5 | 9.24e-01 | -2.47e-02 | 9.73e-01 |
| REACTOME SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS | 14 | 9.25e-01 | 1.45e-02 | 9.74e-01 |
| REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | 10 | 9.27e-01 | 1.67e-02 | 9.76e-01 |
| REACTOME EPH EPHRIN SIGNALING | 90 | 9.29e-01 | 5.46e-03 | 9.77e-01 |
| REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION | 26 | 9.31e-01 | -9.87e-03 | 9.78e-01 |
| REACTOME METAL ION SLC TRANSPORTERS | 23 | 9.32e-01 | -1.02e-02 | 9.78e-01 |
| REACTOME REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION | 9 | 9.33e-01 | 1.63e-02 | 9.78e-01 |
| REACTOME HEMOSTASIS | 591 | 9.33e-01 | -2.02e-03 | 9.78e-01 |
| REACTOME FRUCTOSE METABOLISM | 7 | 9.34e-01 | 1.81e-02 | 9.78e-01 |
| REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA | 25 | 9.34e-01 | -9.55e-03 | 9.78e-01 |
| REACTOME SYNTHESIS OF DOLICHYL PHOSPHATE | 6 | 9.35e-01 | -1.93e-02 | 9.78e-01 |
| REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR3 | 24 | 9.35e-01 | -9.64e-03 | 9.78e-01 |
| REACTOME LDL REMODELING | 6 | 9.36e-01 | -1.90e-02 | 9.78e-01 |
| REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION | 19 | 9.36e-01 | 1.06e-02 | 9.78e-01 |
| REACTOME BETA OXIDATION OF PRISTANOYL COA | 9 | 9.37e-01 | -1.53e-02 | 9.78e-01 |
| REACTOME ORGANIC CATION TRANSPORT | 10 | 9.37e-01 | -1.44e-02 | 9.78e-01 |
| REACTOME NR1H2 AND NR1H3 MEDIATED SIGNALING | 46 | 9.38e-01 | -6.64e-03 | 9.78e-01 |
| REACTOME NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 25 | 9.38e-01 | 8.98e-03 | 9.78e-01 |
| REACTOME REGULATION OF IFNG SIGNALING | 14 | 9.39e-01 | 1.19e-02 | 9.78e-01 |
| REACTOME DISEASES OF BASE EXCISION REPAIR | 5 | 9.39e-01 | -1.97e-02 | 9.78e-01 |
| REACTOME ACTIVATION OF PPARGC1A PGC 1ALPHA BY PHOSPHORYLATION | 10 | 9.41e-01 | -1.36e-02 | 9.78e-01 |
| REACTOME SHC RELATED EVENTS TRIGGERED BY IGF1R | 9 | 9.41e-01 | -1.43e-02 | 9.78e-01 |
| REACTOME REGULATED PROTEOLYSIS OF P75NTR | 11 | 9.41e-01 | 1.29e-02 | 9.78e-01 |
| REACTOME REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO | 10 | 9.42e-01 | -1.34e-02 | 9.78e-01 |
| REACTOME FORMATION OF PARAXIAL MESODERM | 22 | 9.43e-01 | 8.73e-03 | 9.79e-01 |
| REACTOME HEME DEGRADATION | 15 | 9.44e-01 | -1.06e-02 | 9.79e-01 |
| REACTOME COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM | 21 | 9.48e-01 | 8.24e-03 | 9.83e-01 |
| REACTOME ZINC TRANSPORTERS | 15 | 9.50e-01 | -9.26e-03 | 9.83e-01 |
| REACTOME LINOLEIC ACID LA METABOLISM | 7 | 9.51e-01 | 1.34e-02 | 9.83e-01 |
| REACTOME TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY | 30 | 9.52e-01 | -6.38e-03 | 9.83e-01 |
| REACTOME SIGNALING BY MRAS COMPLEX MUTANTS | 7 | 9.52e-01 | 1.32e-02 | 9.83e-01 |
| REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | 21 | 9.52e-01 | -7.54e-03 | 9.83e-01 |
| REACTOME KERATAN SULFATE DEGRADATION | 13 | 9.53e-01 | 9.38e-03 | 9.83e-01 |
| REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND | 21 | 9.53e-01 | -7.38e-03 | 9.83e-01 |
| REACTOME FGFR2B LIGAND BINDING AND ACTIVATION | 10 | 9.54e-01 | -1.04e-02 | 9.83e-01 |
| REACTOME GAP JUNCTION TRAFFICKING AND REGULATION | 49 | 9.55e-01 | 4.66e-03 | 9.83e-01 |
| REACTOME ARACHIDONIC ACID METABOLISM | 57 | 9.55e-01 | -4.27e-03 | 9.83e-01 |
| REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | 17 | 9.56e-01 | 7.80e-03 | 9.83e-01 |
| REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS | 19 | 9.56e-01 | -7.36e-03 | 9.83e-01 |
| REACTOME NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION | 20 | 9.56e-01 | -7.16e-03 | 9.83e-01 |
| REACTOME NOSTRIN MEDIATED ENOS TRAFFICKING | 5 | 9.58e-01 | -1.35e-02 | 9.85e-01 |
| REACTOME INTERLEUKIN 17 SIGNALING | 66 | 9.60e-01 | -3.56e-03 | 9.85e-01 |
| REACTOME COHESIN LOADING ONTO CHROMATIN | 8 | 9.61e-01 | 1.01e-02 | 9.85e-01 |
| REACTOME RAB REGULATION OF TRAFFICKING | 110 | 9.61e-01 | 2.71e-03 | 9.85e-01 |
| REACTOME SULFIDE OXIDATION TO SULFATE | 6 | 9.62e-01 | -1.12e-02 | 9.85e-01 |
| REACTOME TBC RABGAPS | 40 | 9.63e-01 | -4.25e-03 | 9.85e-01 |
| REACTOME LONG TERM POTENTIATION | 22 | 9.63e-01 | -5.67e-03 | 9.85e-01 |
| REACTOME VITAMIN B2 RIBOFLAVIN METABOLISM | 7 | 9.63e-01 | 1.00e-02 | 9.85e-01 |
| REACTOME THE ACTIVATION OF ARYLSULFATASES | 8 | 9.63e-01 | 9.35e-03 | 9.85e-01 |
| REACTOME GLUCOSE METABOLISM | 90 | 9.65e-01 | 2.69e-03 | 9.86e-01 |
| REACTOME ACTIVATION OF TRKA RECEPTORS | 6 | 9.66e-01 | 1.01e-02 | 9.86e-01 |
| REACTOME GOLGI TO ER RETROGRADE TRANSPORT | 132 | 9.68e-01 | 2.02e-03 | 9.88e-01 |
| REACTOME RAF INDEPENDENT MAPK1 3 ACTIVATION | 22 | 9.70e-01 | -4.58e-03 | 9.90e-01 |
| REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING | 29 | 9.72e-01 | -3.78e-03 | 9.91e-01 |
| REACTOME ERKS ARE INACTIVATED | 13 | 9.73e-01 | -5.49e-03 | 9.91e-01 |
| REACTOME CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2 | 11 | 9.73e-01 | -5.86e-03 | 9.91e-01 |
| REACTOME DISEASES OF MISMATCH REPAIR MMR | 5 | 9.74e-01 | 8.53e-03 | 9.91e-01 |
| REACTOME METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS | 122 | 9.75e-01 | 1.65e-03 | 9.91e-01 |
| REACTOME MET ACTIVATES RAS SIGNALING | 11 | 9.76e-01 | -5.25e-03 | 9.92e-01 |
| REACTOME SARS COV 2 MODULATES AUTOPHAGY | 11 | 9.77e-01 | 5.01e-03 | 9.92e-01 |
| REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS | 14 | 9.80e-01 | -3.84e-03 | 9.94e-01 |
| REACTOME ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS | 24 | 9.80e-01 | -2.89e-03 | 9.94e-01 |
| REACTOME SYNTHESIS OF PC | 27 | 9.81e-01 | 2.66e-03 | 9.94e-01 |
| REACTOME SMALL INTERFERING RNA SIRNA BIOGENESIS | 9 | 9.83e-01 | 4.12e-03 | 9.96e-01 |
| REACTOME RAP1 SIGNALLING | 16 | 9.85e-01 | 2.80e-03 | 9.96e-01 |
| REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION | 11 | 9.85e-01 | -3.28e-03 | 9.96e-01 |
| REACTOME RIBAVIRIN ADME | 11 | 9.85e-01 | -3.23e-03 | 9.96e-01 |
| REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1 | 31 | 9.87e-01 | -1.66e-03 | 9.96e-01 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING | 6 | 9.87e-01 | -3.74e-03 | 9.96e-01 |
| REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R | 52 | 9.88e-01 | 1.18e-03 | 9.96e-01 |
| REACTOME ACTIVATION OF AMPK DOWNSTREAM OF NMDARS | 28 | 9.88e-01 | -1.58e-03 | 9.96e-01 |
| REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV 1 INFECTION | 5 | 9.89e-01 | 3.71e-03 | 9.96e-01 |
| REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD4 | 15 | 9.91e-01 | -1.59e-03 | 9.98e-01 |
| REACTOME ATORVASTATIN ADME | 9 | 9.92e-01 | 2.04e-03 | 9.98e-01 |
| REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION | 31 | 9.92e-01 | 1.01e-03 | 9.98e-01 |
| REACTOME SIGNALING BY KIT IN DISEASE | 20 | 9.93e-01 | -1.14e-03 | 9.98e-01 |
| REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS | 11 | 9.93e-01 | -1.50e-03 | 9.98e-01 |
| REACTOME SUMOYLATION OF TRANSCRIPTION FACTORS | 20 | 9.93e-01 | 1.09e-03 | 9.98e-01 |
| REACTOME FRUCTOSE CATABOLISM | 5 | 9.95e-01 | 1.64e-03 | 9.98e-01 |
| REACTOME SIGNALING BY ERBB2 ECD MUTANTS | 16 | 9.95e-01 | -8.87e-04 | 9.98e-01 |
| REACTOME BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS | 10 | 9.96e-01 | 1.00e-03 | 9.98e-01 |
| REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | 22 | 9.96e-01 | 6.29e-04 | 9.98e-01 |
| REACTOME NECTIN NECL TRANS HETERODIMERIZATION | 7 | 9.97e-01 | 8.57e-04 | 9.98e-01 |
| REACTOME MITOCHONDRIAL UNCOUPLING | 5 | 9.97e-01 | -9.09e-04 | 9.98e-01 |
| REACTOME NONCANONICAL ACTIVATION OF NOTCH3 | 8 | 1.00e+00 | -1.14e-05 | 1.00e+00 |
Detailed Gene set reports
REACTOME_TRANSLATION
| 1152 | |
|---|---|
| set | REACTOME_TRANSLATION |
| setSize | 278 |
| pANOVA | 3.79e-22 |
| s.dist | 0.337 |
| p.adjustANOVA | 5.52e-19 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL39L | 10429 |
| SEC61B | 10414 |
| CHCHD1 | 10402 |
| RPLP1 | 10383 |
| EIF2B1 | 10258 |
| RPL19 | 10237 |
| RPL27A | 10126 |
| RPL38 | 10097 |
| MRPL53 | 10073 |
| RPS12 | 10065 |
| RPL27 | 10018 |
| EIF3J | 9988 |
| RPL12 | 9972 |
| EIF2B4 | 9865 |
| RPL5 | 9847 |
| RPL10A | 9823 |
| MRPL9 | 9777 |
| MRPL16 | 9735 |
| EIF4A1 | 9700 |
| RPSA | 9598 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL39L | 10429.0 |
| SEC61B | 10414.0 |
| CHCHD1 | 10402.0 |
| RPLP1 | 10383.0 |
| EIF2B1 | 10258.0 |
| RPL19 | 10237.0 |
| RPL27A | 10126.0 |
| RPL38 | 10097.0 |
| MRPL53 | 10073.0 |
| RPS12 | 10065.0 |
| RPL27 | 10018.0 |
| EIF3J | 9988.0 |
| RPL12 | 9972.0 |
| EIF2B4 | 9865.0 |
| RPL5 | 9847.0 |
| RPL10A | 9823.0 |
| MRPL9 | 9777.0 |
| MRPL16 | 9735.0 |
| EIF4A1 | 9700.0 |
| RPSA | 9598.0 |
| MRPL33 | 9537.0 |
| MTIF2 | 9535.0 |
| MRPL12 | 9513.0 |
| MRPL39 | 9512.0 |
| EEF1A1 | 9508.0 |
| RPL35A | 9504.0 |
| MRPL17 | 9402.0 |
| RPL13 | 9355.0 |
| MRPL37 | 9347.0 |
| MRPL57 | 9283.0 |
| SEC61G | 9264.0 |
| RPL11 | 9263.0 |
| EEF1B2 | 9172.0 |
| YARS2 | 9112.0 |
| RPL34 | 8949.0 |
| MARS2 | 8889.0 |
| MRPS16 | 8881.0 |
| EIF5B | 8800.0 |
| MRPL27 | 8779.0 |
| ETF1 | 8741.0 |
| EIF4H | 8713.0 |
| EIF2S2 | 8700.0 |
| EIF2S1 | 8607.0 |
| MRPL19 | 8606.0 |
| RPL36AL | 8546.5 |
| TUFM | 8502.0 |
| SRP54 | 8446.0 |
| RPL18A | 8433.0 |
| RPS18 | 8418.0 |
| RPL7 | 8407.0 |
| RPS14 | 8367.0 |
| NARS1 | 8357.0 |
| MRPS11 | 8329.0 |
| MRPL30 | 8313.0 |
| EEF1E1 | 8291.0 |
| MRPL11 | 8262.0 |
| MRPS7 | 8128.0 |
| RPL37 | 8126.0 |
| SRP9 | 8055.0 |
| RPS28 | 8053.0 |
| GFM1 | 8025.0 |
| MRPS12 | 8009.0 |
| MRPS9 | 8006.0 |
| RPL7A | 7958.0 |
| SPCS1 | 7856.0 |
| RPL23 | 7819.0 |
| SSR2 | 7799.0 |
| SEC11C | 7794.0 |
| LARS1 | 7756.0 |
| WARS2 | 7628.0 |
| SEC11A | 7606.0 |
| RPL6 | 7585.0 |
| HARS2 | 7525.0 |
| RPL28 | 7492.0 |
| RPLP0 | 7456.0 |
| RPS10 | 7422.0 |
| EIF2B2 | 7382.0 |
| MRPL34 | 7304.0 |
| RPS9 | 7239.0 |
| RPL3 | 7066.0 |
| MRPL36 | 7032.0 |
| EIF2B5 | 7028.0 |
| MRPS15 | 6903.0 |
| UBA52 | 6901.0 |
| RPL4 | 6839.0 |
| MRPL54 | 6785.0 |
| MRPL46 | 6781.0 |
| RPL23A | 6780.0 |
| RPS13 | 6745.0 |
| EEF1A2 | 6733.0 |
| MRPL50 | 6723.0 |
| RPL32 | 6717.0 |
| MRPS17 | 6590.0 |
| FARSA | 6537.0 |
| MRPL42 | 6514.0 |
| EIF3G | 6501.0 |
| MTIF3 | 6487.0 |
| WARS1 | 6462.0 |
| TRAM1 | 6417.0 |
| MRPL40 | 6374.0 |
| MTRF1L | 6362.0 |
| SRP19 | 6332.0 |
| RPS21 | 6312.0 |
| EIF3F | 6280.0 |
| RPS27A | 6223.0 |
| RPS23 | 6171.0 |
| RPS2 | 6145.0 |
| RPL8 | 6083.0 |
| MRPL18 | 6071.0 |
| RPS3A | 5876.0 |
| AIMP1 | 5852.0 |
| MRPL51 | 5803.0 |
| EIF3K | 5774.0 |
| SEC61A1 | 5685.0 |
| SARS2 | 5662.0 |
| RPS27L | 5650.0 |
| MRPL10 | 5637.0 |
| MRPL24 | 5568.0 |
| RPS16 | 5552.0 |
| OXA1L | 5550.0 |
| PARS2 | 5522.0 |
| PPA1 | 5521.0 |
| SSR3 | 5516.0 |
| DARS2 | 5440.0 |
| MRPL41 | 5416.0 |
| RPL15 | 5410.0 |
| MRPL48 | 5398.0 |
| YARS1 | 5385.0 |
| FAU | 5376.0 |
| MRPS30 | 5321.0 |
| EIF3I | 5206.0 |
| EEF1G | 5173.0 |
| FARSB | 5141.0 |
| SRP14 | 5116.0 |
| MRPL21 | 5072.0 |
| PTCD3 | 5058.0 |
| MRPS18B | 4983.0 |
| EIF4E | 4924.0 |
| MRPS31 | 4881.0 |
| RPL18 | 4825.0 |
| MRPS18A | 4762.0 |
| MRPL2 | 4587.0 |
| RPL26 | 4557.0 |
| DARS1 | 4553.0 |
| RPL17 | 4473.0 |
| RPS11 | 4468.0 |
| RPL21 | 4396.0 |
| NARS2 | 4254.0 |
| SPCS2 | 4240.0 |
| RPS20 | 4174.0 |
| RPS15A | 4169.0 |
| RPS8 | 4117.0 |
| KARS1 | 4073.0 |
| RPL30 | 3957.0 |
| MRPS34 | 3939.0 |
| SRP72 | 3890.0 |
| EARS2 | 3804.0 |
| MRPL49 | 3773.0 |
| RPL26L1 | 3710.0 |
| EIF3L | 3580.0 |
| RPS19 | 3558.0 |
| RPS5 | 3408.0 |
| RPS24 | 3357.0 |
| RPS7 | 3333.0 |
| EIF4A2 | 3182.0 |
| MRPL47 | 3144.0 |
| PPA2 | 3108.0 |
| RPL37A | 3063.0 |
| RPN1 | 2950.0 |
| RPL22 | 2864.0 |
| RPS29 | 2812.0 |
| MRPL32 | 2795.0 |
| MRPL44 | 2765.0 |
| RPL35 | 2694.0 |
| MRPS22 | 2657.0 |
| RPS26 | 2583.0 |
| RPS27 | 2232.0 |
| MRPL15 | 2223.0 |
| VARS2 | 2072.0 |
| RPS25 | 2059.0 |
| MRPS24 | 2005.0 |
| AURKAIP1 | 1928.0 |
| RARS1 | 1805.0 |
| RPL22L1 | 1785.0 |
| MRPL22 | 1751.0 |
| DAP3 | 1744.0 |
| MRPS5 | 1711.0 |
| GSPT1 | 1694.0 |
| MRPL20 | 1351.0 |
| EIF5 | 1315.0 |
| RPS6 | 1237.0 |
| MRPL52 | 1112.0 |
| MRPS35 | 1015.0 |
| RPL24 | 901.0 |
| HARS1 | 888.0 |
| MRPL45 | 865.0 |
| MRPS25 | 796.0 |
| MRPS18C | 702.0 |
| GADD45GIP1 | 678.0 |
| MRPL3 | 579.0 |
| EIF3M | 574.0 |
| MRPS23 | 488.0 |
| TRMT112 | 296.0 |
| PABPC1 | 181.0 |
| EIF4G1 | 169.0 |
| RPLP2 | 141.0 |
| SPCS3 | 5.0 |
| TARS1 | -83.0 |
| EIF3E | -214.0 |
| SRPRA | -245.0 |
| MRPS28 | -257.0 |
| RPL9 | -399.0 |
| MRPS26 | -626.0 |
| RPL29 | -634.0 |
| GARS1 | -692.0 |
| MRPS6 | -700.0 |
| RPL36 | -891.0 |
| RPS3 | -935.0 |
| N6AMT1 | -1027.0 |
| MRPL14 | -1050.0 |
| RARS2 | -1096.0 |
| SRP68 | -1319.0 |
| RPN2 | -1352.0 |
| MRPL28 | -1679.0 |
| SSR1 | -1706.0 |
| EIF4B | -1756.0 |
| MRPL13 | -1774.0 |
| MRPL1 | -1960.0 |
| LARS2 | -2058.0 |
| MRPS27 | -2079.0 |
| GFM2 | -2086.0 |
| MRPS10 | -2284.0 |
| TARS2 | -2363.0 |
| RPL41 | -2639.0 |
| RPL13A | -2765.5 |
| RPS15 | -2768.0 |
| MRPL58 | -3033.0 |
| MRPL43 | -3053.0 |
| MRPS33 | -3305.0 |
| MRPL55 | -3401.0 |
| RPL31 | -3475.0 |
| MRPL4 | -3483.0 |
| EIF2B3 | -3754.0 |
| MTFMT | -3793.0 |
| ERAL1 | -3900.0 |
| MRPL35 | -3947.0 |
| TSFM | -3971.0 |
| EPRS1 | -4013.0 |
| CARS2 | -4102.0 |
| MRRF | -4195.0 |
| APEH | -4358.0 |
| EIF3D | -4500.0 |
| SRPRB | -4503.0 |
| AIMP2 | -4699.0 |
| MRPS2 | -4820.0 |
| EEF2 | -4923.0 |
| IARS2 | -5713.0 |
| MRPS21 | -5738.0 |
| RPL14 | -5770.0 |
| EIF3B | -6053.0 |
| AARS1 | -6315.0 |
| VARS1 | -6384.0 |
| EIF4EBP1 | -6620.0 |
| AARS2 | -6761.0 |
| IARS1 | -6986.0 |
| EIF3A | -7122.0 |
| DDOST | -7370.0 |
| EIF3H | -7385.0 |
| FARS2 | -8039.0 |
| MRPL38 | -8236.0 |
| MARS1 | -8262.0 |
| MRPS14 | -8328.0 |
| SEC61A2 | -8538.0 |
| MRPL23 | -8657.0 |
| CARS1 | -8691.0 |
| EEF1D | -9713.0 |
| RPL3L | -10862.0 |
| RPL10L | -10981.0 |
REACTOME_METABOLISM_OF_RNA
| 1313 | |
|---|---|
| set | REACTOME_METABOLISM_OF_RNA |
| setSize | 675 |
| pANOVA | 6.72e-22 |
| s.dist | 0.217 |
| p.adjustANOVA | 5.52e-19 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL39L | 10429 |
| RPLP1 | 10383 |
| TRMT61B | 10351 |
| UBB | 10269 |
| RPL19 | 10237 |
| ZMAT2 | 10215 |
| RRP36 | 10144 |
| RPL27A | 10126 |
| PRPF19 | 10124 |
| RPL38 | 10097 |
| A1CF | 10084 |
| DCP2 | 10068 |
| RPS12 | 10065 |
| RPL27 | 10018 |
| RPPH1 | 10013 |
| FAM32A | 9973 |
| RPL12 | 9972 |
| RPP25 | 9956 |
| MRM1 | 9938 |
| RPL5 | 9847 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL39L | 10429.0 |
| RPLP1 | 10383.0 |
| TRMT61B | 10351.0 |
| UBB | 10269.0 |
| RPL19 | 10237.0 |
| ZMAT2 | 10215.0 |
| RRP36 | 10144.0 |
| RPL27A | 10126.0 |
| PRPF19 | 10124.0 |
| RPL38 | 10097.0 |
| A1CF | 10084.0 |
| DCP2 | 10068.0 |
| RPS12 | 10065.0 |
| RPL27 | 10018.0 |
| RPPH1 | 10013.0 |
| FAM32A | 9973.0 |
| RPL12 | 9972.0 |
| RPP25 | 9956.0 |
| MRM1 | 9938.0 |
| RPL5 | 9847.0 |
| RPL10A | 9823.0 |
| GAR1 | 9822.0 |
| SRSF1 | 9784.0 |
| APOBEC3A | 9751.0 |
| GTF2H3 | 9734.0 |
| SNRPF | 9718.0 |
| EIF4A1 | 9700.0 |
| SKIC8 | 9652.0 |
| RPSA | 9598.0 |
| ANP32A | 9558.0 |
| POP5 | 9517.0 |
| RPL35A | 9504.0 |
| POP7 | 9490.0 |
| HNRNPL | 9450.0 |
| PRKRIP1 | 9431.0 |
| MPHOSPH10 | 9428.0 |
| SRSF10 | 9381.0 |
| TPR | 9369.0 |
| TRNT1 | 9359.0 |
| RPL13 | 9355.0 |
| NUP35 | 9338.0 |
| NXT1 | 9315.0 |
| PSMB3 | 9282.0 |
| DDX20 | 9274.0 |
| RPL11 | 9263.0 |
| GEMIN2 | 9249.0 |
| NUP107 | 9241.0 |
| PCBP1 | 9188.0 |
| PATL1 | 9183.0 |
| APOBEC3C | 9181.0 |
| QTRT2 | 9137.0 |
| RBM8A | 9093.0 |
| PSMA6 | 9088.0 |
| EMG1 | 9083.0 |
| ZFP36L1 | 8993.0 |
| RPL34 | 8949.0 |
| PSMA7 | 8947.0 |
| ISG20L2 | 8946.0 |
| SET | 8922.0 |
| XPOT | 8896.0 |
| POLR2L | 8803.0 |
| CRNKL1 | 8786.0 |
| APOBEC3B | 8772.0 |
| ETF1 | 8741.0 |
| PSME2 | 8738.0 |
| NUP43 | 8731.0 |
| ISY1 | 8721.0 |
| LENG1 | 8714.0 |
| PSMC5 | 8695.0 |
| UBC | 8680.0 |
| PSMA1 | 8676.0 |
| PRPF38A | 8667.0 |
| APOBEC1 | 8636.0 |
| LUC7L3 | 8627.0 |
| RPL36AL | 8546.5 |
| MAPK14 | 8531.0 |
| POLR2D | 8521.0 |
| POLR2C | 8482.0 |
| RPL18A | 8433.0 |
| PAN3 | 8423.0 |
| RPS18 | 8418.0 |
| UTP15 | 8413.0 |
| RPL7 | 8407.0 |
| PSMD12 | 8377.0 |
| RPP40 | 8373.0 |
| RPS14 | 8367.0 |
| PCBP2 | 8264.0 |
| ZNF473 | 8246.0 |
| CNOT11 | 8234.0 |
| CSTF2T | 8207.0 |
| PDCD11 | 8186.0 |
| SRSF6 | 8166.0 |
| NUP153 | 8165.0 |
| PSMB1 | 8157.0 |
| PAIP1 | 8154.0 |
| SNRPD2 | 8144.0 |
| EXOSC1 | 8143.0 |
| CDC40 | 8132.0 |
| RPL37 | 8126.0 |
| UPF2 | 8123.0 |
| RNMT | 8078.0 |
| HSPA1A | 8066.0 |
| PPIH | 8060.0 |
| RPS28 | 8053.0 |
| PSMC4 | 8042.0 |
| MPHOSPH6 | 7977.0 |
| RPL7A | 7958.0 |
| RRP9 | 7942.0 |
| THOC1 | 7863.0 |
| PPIG | 7844.0 |
| RPL23 | 7819.0 |
| DDX49 | 7784.0 |
| HSPA8 | 7776.0 |
| CLP1 | 7758.0 |
| SNRPD3 | 7673.0 |
| POLR2I | 7672.0 |
| NUP155 | 7642.0 |
| RPL6 | 7585.0 |
| XPO1 | 7555.0 |
| SNRNP25 | 7507.0 |
| TRMT10A | 7506.0 |
| RPL28 | 7492.0 |
| RPP30 | 7478.0 |
| SARNP | 7472.0 |
| RPLP0 | 7456.0 |
| LSM6 | 7450.0 |
| EBNA1BP2 | 7448.0 |
| RPS10 | 7422.0 |
| UBL5 | 7408.0 |
| NIP7 | 7371.0 |
| GCFC2 | 7366.0 |
| PAPOLA | 7352.0 |
| FTSJ3 | 7351.0 |
| ZCRB1 | 7346.0 |
| CWC15 | 7329.0 |
| POLR2H | 7324.0 |
| EXOSC5 | 7283.0 |
| U2SURP | 7274.0 |
| EXOSC7 | 7271.0 |
| SYMPK | 7264.0 |
| DDX52 | 7242.0 |
| RPS9 | 7239.0 |
| TP53RK | 7228.0 |
| OSGEP | 7223.0 |
| RBM22 | 7220.0 |
| WBP11 | 7210.0 |
| PSMB9 | 7201.0 |
| ZBTB8OS | 7194.0 |
| TRIT1 | 7091.0 |
| RPL3 | 7066.0 |
| NOL11 | 6973.0 |
| SNRPA | 6969.0 |
| IK | 6968.0 |
| HNRNPA1 | 6967.0 |
| EXOSC3 | 6924.0 |
| THOC6 | 6907.0 |
| UBA52 | 6901.0 |
| GEMIN6 | 6871.0 |
| PTBP1 | 6857.0 |
| PPIL1 | 6856.0 |
| RPL4 | 6839.0 |
| HBS1L | 6809.0 |
| LSM5 | 6808.0 |
| HNRNPA2B1 | 6790.0 |
| RPL23A | 6780.0 |
| HNRNPF | 6777.0 |
| RPS13 | 6745.0 |
| PPIL3 | 6738.0 |
| RPL32 | 6717.0 |
| PUS7 | 6711.0 |
| DDX21 | 6692.0 |
| FYTTD1 | 6681.0 |
| SNW1 | 6642.0 |
| MFAP1 | 6580.0 |
| LSM4 | 6570.0 |
| SMG1 | 6516.0 |
| DIS3 | 6405.0 |
| WDR3 | 6395.0 |
| GTPBP3 | 6344.0 |
| DDX6 | 6318.0 |
| RPS21 | 6312.0 |
| PRPF40A | 6288.0 |
| PSMB7 | 6283.0 |
| RPS27A | 6223.0 |
| CWC22 | 6219.0 |
| PSMB10 | 6211.0 |
| EXOSC4 | 6174.0 |
| RPS23 | 6171.0 |
| ZFP36 | 6170.0 |
| RPS2 | 6145.0 |
| RPL8 | 6083.0 |
| DCAF13 | 6081.0 |
| UTP11 | 6058.0 |
| YWHAZ | 6039.0 |
| POLR2E | 6038.0 |
| CNOT9 | 6037.0 |
| HNRNPD | 6019.0 |
| CSTF1 | 6015.0 |
| PSMB8 | 6003.0 |
| EXOSC8 | 5963.0 |
| LSM11 | 5952.0 |
| PSMD13 | 5916.0 |
| SNUPN | 5890.0 |
| SNRNP27 | 5885.0 |
| RPS3A | 5876.0 |
| TNFSF13 | 5820.0 |
| ADAT2 | 5781.0 |
| TGS1 | 5759.0 |
| PCF11 | 5722.0 |
| UTP18 | 5677.0 |
| NUP54 | 5663.0 |
| RPS27L | 5650.0 |
| CPSF2 | 5646.0 |
| CCNH | 5625.0 |
| TRMT5 | 5569.0 |
| RPS16 | 5552.0 |
| SF3A2 | 5538.0 |
| NUP50 | 5527.0 |
| WTAP | 5485.0 |
| METTL14 | 5456.0 |
| PSMC6 | 5420.0 |
| RPL15 | 5410.0 |
| PHF5A | 5381.0 |
| FAU | 5376.0 |
| POLR2K | 5369.0 |
| PAN2 | 5285.0 |
| SNRNP35 | 5272.0 |
| PUS3 | 5258.0 |
| PRPF4 | 5243.0 |
| DUS2 | 5231.0 |
| SUPT5H | 5131.0 |
| HNRNPR | 5086.0 |
| POP1 | 5063.0 |
| TRMT1 | 4975.0 |
| PSMA4 | 4963.0 |
| PSMD7 | 4932.0 |
| EIF4E | 4924.0 |
| EDC3 | 4834.0 |
| RPL18 | 4825.0 |
| NXF1 | 4820.0 |
| DDX39A | 4808.0 |
| PNRC2 | 4795.0 |
| DHX9 | 4760.0 |
| PRMT5 | 4742.0 |
| PDCD7 | 4704.0 |
| NCBP1 | 4593.0 |
| RPL26 | 4557.0 |
| RPP38 | 4515.0 |
| C2orf49 | 4504.0 |
| RPL17 | 4473.0 |
| RPS11 | 4468.0 |
| USP39 | 4454.0 |
| ADAT3 | 4452.0 |
| PPWD1 | 4404.0 |
| RPL21 | 4396.0 |
| POM121 | 4393.0 |
| PRCC | 4383.0 |
| RBM7 | 4367.0 |
| PNO1 | 4358.0 |
| THOC5 | 4309.0 |
| CWC27 | 4280.0 |
| PNN | 4274.0 |
| ADAT1 | 4262.0 |
| RPS20 | 4174.0 |
| RPS15A | 4169.0 |
| RPS8 | 4117.0 |
| PSMA3 | 4116.0 |
| SRSF2 | 4105.0 |
| TRMT6 | 4063.0 |
| BUD31 | 4041.0 |
| WBP4 | 4019.0 |
| TRMT11 | 4013.0 |
| FCF1 | 3969.0 |
| RPL30 | 3957.0 |
| BUD23 | 3955.0 |
| NCL | 3954.0 |
| SMNDC1 | 3925.0 |
| TNPO1 | 3866.0 |
| SF3A3 | 3848.0 |
| POM121C | 3776.0 |
| SYF2 | 3763.0 |
| SRSF3 | 3757.0 |
| CPSF6 | 3738.0 |
| RPL26L1 | 3710.0 |
| C9orf78 | 3702.0 |
| RAN | 3664.0 |
| KHSRP | 3662.0 |
| CLNS1A | 3646.0 |
| DIMT1 | 3607.0 |
| SMG7 | 3596.0 |
| RPS19 | 3558.0 |
| GTF2H4 | 3554.0 |
| RBM17 | 3546.0 |
| SF3B5 | 3485.0 |
| IMP3 | 3475.0 |
| IMP4 | 3465.0 |
| HSPB1 | 3432.0 |
| NUP133 | 3422.0 |
| WDR75 | 3416.0 |
| RPS5 | 3408.0 |
| RBM39 | 3399.0 |
| RPS24 | 3357.0 |
| RPS7 | 3333.0 |
| PSMB2 | 3326.0 |
| LSM1 | 3306.0 |
| CPSF3 | 3298.0 |
| SF3B1 | 3294.0 |
| HNRNPU | 3260.0 |
| RIOK2 | 3233.0 |
| DHX8 | 3228.0 |
| NUP205 | 3185.0 |
| EIF4A2 | 3182.0 |
| POLDIP3 | 3152.0 |
| LSM7 | 3122.0 |
| SNRPB2 | 3100.0 |
| CDC5L | 3089.0 |
| RPL37A | 3063.0 |
| PSMB4 | 3049.0 |
| MTREX | 2997.0 |
| PSMC1 | 2987.0 |
| DCPS | 2984.0 |
| SNRPA1 | 2983.0 |
| GPATCH1 | 2966.0 |
| GTF2H5 | 2954.0 |
| WDR33 | 2922.0 |
| ZNF830 | 2871.0 |
| RPL22 | 2864.0 |
| TRMT61A | 2863.0 |
| TRA2B | 2818.0 |
| RPS29 | 2812.0 |
| ALYREF | 2764.0 |
| TYW5 | 2756.0 |
| LTV1 | 2704.0 |
| RPL35 | 2694.0 |
| U2AF1L4 | 2692.0 |
| IGF2BP2 | 2656.0 |
| RIOK3 | 2652.0 |
| ZMAT5 | 2645.0 |
| NUDT21 | 2618.0 |
| RPS26 | 2583.0 |
| HNRNPA3 | 2549.0 |
| SRSF11 | 2478.0 |
| UTP20 | 2466.0 |
| MNAT1 | 2449.0 |
| GTF2H1 | 2440.0 |
| NT5C3B | 2433.0 |
| BUD13 | 2428.0 |
| SNRPN | 2421.0 |
| NDC1 | 2410.0 |
| UTP4 | 2397.0 |
| NSRP1 | 2385.0 |
| PSMA8 | 2379.0 |
| CWC25 | 2378.0 |
| TSEN34 | 2326.0 |
| ACIN1 | 2310.0 |
| SENP3 | 2305.0 |
| BYSL | 2302.0 |
| CNOT6L | 2292.0 |
| NAT10 | 2275.0 |
| TRMT13 | 2271.0 |
| UTP6 | 2239.0 |
| CSTF3 | 2236.0 |
| RPS27 | 2232.0 |
| CTU1 | 2231.0 |
| CCDC12 | 2213.0 |
| RTRAF | 2163.0 |
| SMG6 | 2149.0 |
| PSMD1 | 2144.0 |
| POLR2G | 2138.0 |
| PSME4 | 2128.0 |
| SRRM1 | 2110.0 |
| TSR1 | 2106.0 |
| PELP1 | 2083.0 |
| PSMB5 | 2078.0 |
| RPS25 | 2059.0 |
| CNOT2 | 2047.0 |
| HNRNPH1 | 2042.0 |
| SDE2 | 2032.0 |
| KRR1 | 2025.0 |
| UPF3A | 1945.0 |
| SLBP | 1943.0 |
| SMG8 | 1902.0 |
| TPRKB | 1876.0 |
| CNOT8 | 1860.0 |
| PRPF6 | 1851.0 |
| RPL22L1 | 1785.0 |
| MAGOH | 1757.0 |
| PSMC3 | 1749.0 |
| DDX46 | 1735.0 |
| CCAR1 | 1712.0 |
| GSPT1 | 1694.0 |
| SRSF7 | 1680.0 |
| NOP10 | 1673.0 |
| DDX5 | 1661.0 |
| SEM1 | 1657.0 |
| PSMC2 | 1653.0 |
| IGF2BP1 | 1646.0 |
| HNRNPM | 1584.0 |
| SNRNP70 | 1557.0 |
| NCBP2 | 1556.0 |
| CASC3 | 1522.0 |
| WDR43 | 1490.0 |
| EFTUD2 | 1479.0 |
| TXNL4A | 1452.0 |
| BCAS2 | 1451.0 |
| SNRNP48 | 1448.0 |
| PSMD4 | 1403.0 |
| CNOT7 | 1393.0 |
| IGF2BP3 | 1371.0 |
| NUP88 | 1277.0 |
| RPS6 | 1237.0 |
| NOL12 | 1230.0 |
| RAE1 | 1215.0 |
| SMG9 | 1200.0 |
| RANBP2 | 1191.0 |
| HNRNPC | 1166.0 |
| SF3B3 | 1141.0 |
| RNPS1 | 1122.0 |
| DCP1A | 1119.0 |
| PWP2 | 1092.0 |
| RPP21 | 1084.0 |
| FAM98B | 1073.0 |
| TUT4 | 1072.0 |
| SNRPE | 1062.0 |
| RPP14 | 1018.0 |
| UTP25 | 966.0 |
| CDK7 | 909.0 |
| RPL24 | 901.0 |
| METTL3 | 866.0 |
| DHX35 | 820.0 |
| PRKCD | 775.0 |
| SRSF8 | 703.0 |
| PSMA5 | 665.0 |
| PLRG1 | 664.0 |
| PRORP | 643.0 |
| DCP1B | 623.0 |
| NUP160 | 618.0 |
| MTERF4 | 505.0 |
| PSMA2 | 467.0 |
| DDX23 | 412.0 |
| QTRT1 | 406.0 |
| FUS | 375.0 |
| NUP98 | 368.0 |
| NOP58 | 358.0 |
| TRMT112 | 296.0 |
| PSMD3 | 274.0 |
| WDR77 | 190.0 |
| SNIP1 | 182.0 |
| PABPC1 | 181.0 |
| EIF4G1 | 169.0 |
| PPP2R1A | 156.0 |
| RPLP2 | 141.0 |
| LSM3 | 93.0 |
| ZC3H11A | 85.0 |
| SRSF5 | 65.0 |
| MRM3 | 36.0 |
| YBX1 | 28.0 |
| SF3A1 | 15.0 |
| SNRNP40 | -4.0 |
| GEMIN7 | -95.0 |
| CWF19L2 | -145.0 |
| RNPC3 | -184.0 |
| PSMD14 | -192.0 |
| NSUN4 | -225.0 |
| ALKBH8 | -324.0 |
| RPL9 | -399.0 |
| LCMT2 | -405.0 |
| PSME3 | -576.0 |
| WDR4 | -578.0 |
| RPL29 | -634.0 |
| AQR | -674.0 |
| HNRNPK | -680.0 |
| SEH1L | -682.0 |
| UTP3 | -708.0 |
| MAGOHB | -712.0 |
| LSM10 | -794.0 |
| CNOT1 | -819.0 |
| PSME1 | -840.0 |
| DNAJC8 | -868.0 |
| RPL36 | -891.0 |
| UPF1 | -897.0 |
| METTL1 | -916.0 |
| RPS3 | -935.0 |
| PRPF31 | -965.0 |
| PARN | -1017.0 |
| PSMD6 | -1076.0 |
| SF3B2 | -1084.0 |
| SF3B4 | -1087.0 |
| PSMD11 | -1095.0 |
| NUP42 | -1128.0 |
| ERI1 | -1151.0 |
| THUMPD1 | -1189.0 |
| TSEN54 | -1236.0 |
| PPP2CA | -1246.0 |
| CNOT4 | -1262.0 |
| LSM2 | -1401.0 |
| TYW3 | -1406.0 |
| SMN1 | -1491.5 |
| SMN2 | -1491.5 |
| CNOT10 | -1509.0 |
| LSM8 | -1515.0 |
| RBM42 | -1555.0 |
| ERCC3 | -1589.0 |
| PSMD5 | -1600.0 |
| YWHAB | -1708.0 |
| PSMD8 | -1715.0 |
| EIF4B | -1756.0 |
| NUP37 | -1790.0 |
| GTF2F1 | -1794.0 |
| RIOK1 | -1831.0 |
| RBM28 | -1859.0 |
| NOP2 | -1886.0 |
| PSMD9 | -1897.0 |
| PPIL4 | -1912.0 |
| NHP2 | -1967.0 |
| MAPKAPK2 | -1995.0 |
| BMS1 | -2070.0 |
| DDX39B | -2196.0 |
| RTCB | -2211.0 |
| PPP1R8 | -2264.0 |
| TSEN15 | -2289.0 |
| UTP14C | -2301.0 |
| SEC13 | -2354.0 |
| GTF2F2 | -2395.0 |
| PHAX | -2405.0 |
| APOBEC4 | -2484.0 |
| GEMIN4 | -2600.0 |
| RPL41 | -2639.0 |
| SAP18 | -2669.0 |
| CDKAL1 | -2756.0 |
| RPL13A | -2765.5 |
| RPS15 | -2768.0 |
| BOP1 | -2773.0 |
| MTO1 | -2818.0 |
| SKIC3 | -2965.0 |
| EXOSC9 | -3019.0 |
| CNOT6 | -3070.0 |
| RBM25 | -3073.0 |
| THG1L | -3101.0 |
| TUT7 | -3107.0 |
| WDR12 | -3116.0 |
| PRPF18 | -3131.0 |
| DDX1 | -3324.0 |
| ADAR | -3345.0 |
| THADA | -3370.0 |
| RPL31 | -3475.0 |
| GNL3 | -3556.0 |
| POLR2B | -3675.0 |
| PRKCA | -3721.0 |
| SMG5 | -3786.0 |
| CSNK1E | -3790.0 |
| TNKS1BP1 | -3825.0 |
| PRPF8 | -3832.0 |
| DDX47 | -3839.0 |
| SNRPG | -3880.0 |
| EPRS1 | -4013.0 |
| DHX16 | -4101.0 |
| DDX42 | -4112.0 |
| TRMT9B | -4120.0 |
| CTU2 | -4129.0 |
| EXOSC2 | -4135.0 |
| SF1 | -4165.0 |
| SMU1 | -4169.0 |
| PSMF1 | -4178.0 |
| SNU13 | -4219.0 |
| MAPK11 | -4242.0 |
| FIP1L1 | -4270.0 |
| WDR46 | -4361.0 |
| XRN2 | -4395.0 |
| PABPN1 | -4462.0 |
| RNGTT | -4464.0 |
| NUP214 | -4467.0 |
| SNRPC | -4491.0 |
| NOP56 | -4515.0 |
| PPP2R2A | -4580.0 |
| NSUN6 | -4594.0 |
| PES1 | -4679.0 |
| TRMU | -4703.0 |
| WDR36 | -4739.0 |
| XAB2 | -4792.0 |
| HEATR1 | -4821.0 |
| PUS1 | -4880.0 |
| SRSF4 | -4901.0 |
| GLE1 | -4935.0 |
| C1D | -4987.0 |
| XRN1 | -4996.0 |
| TCERG1 | -4997.0 |
| DHX38 | -5092.0 |
| TSEN2 | -5128.0 |
| TRMT12 | -5146.0 |
| NUP93 | -5201.0 |
| POLR2F | -5251.0 |
| TEX10 | -5260.0 |
| URM1 | -5294.0 |
| TFIP11 | -5351.0 |
| PSMB6 | -5356.0 |
| CTNNBL1 | -5418.0 |
| RCL1 | -5420.0 |
| TRMT10C | -5453.0 |
| THOC3 | -5567.0 |
| GEMIN5 | -5594.0 |
| SF3B6 | -5635.0 |
| CACTIN | -5757.0 |
| RPL14 | -5770.0 |
| NOL9 | -5809.0 |
| THOC7 | -5923.0 |
| NUP62 | -6129.0 |
| PSMD2 | -6144.0 |
| EXOSC6 | -6161.0 |
| SLU7 | -6202.0 |
| WDR18 | -6243.0 |
| MRM2 | -6261.0 |
| CHTOP | -6317.0 |
| DHX15 | -6401.0 |
| SNRPB | -6416.0 |
| EXOSC10 | -6450.0 |
| CPSF7 | -6485.0 |
| WDR70 | -6498.0 |
| NSUN2 | -6538.0 |
| NOC4L | -6564.0 |
| RBM5 | -6661.0 |
| YJU2 | -6684.0 |
| SNRPD1 | -6773.0 |
| TRDMT1 | -6793.0 |
| SRSF12 | -6877.0 |
| DHX37 | -6904.0 |
| ADARB1 | -6964.0 |
| CPSF4 | -7119.0 |
| NUP188 | -7120.0 |
| SUGP1 | -7162.0 |
| U2AF2 | -7309.0 |
| NOB1 | -7323.0 |
| RRP7A | -7481.0 |
| CPSF1 | -7597.0 |
| SKIC2 | -7637.0 |
| PUF60 | -7700.0 |
| FBL | -7753.0 |
| NUP58 | -7794.0 |
| TYW1 | -7818.0 |
| NOP14 | -7895.0 |
| RRP1 | -7909.0 |
| PPIL2 | -7929.0 |
| ELAVL1 | -7938.0 |
| NOL6 | -7992.0 |
| ELAC2 | -8034.0 |
| ERCC2 | -8106.0 |
| TSR3 | -8124.0 |
| SRRT | -8192.0 |
| POLR2A | -8208.0 |
| NUP85 | -8221.0 |
| PPIE | -8228.0 |
| AAAS | -8286.0 |
| SRSF9 | -8494.0 |
| NUP210 | -8505.0 |
| PRPF3 | -8612.0 |
| EIF4A3 | -8763.0 |
| APOBEC2 | -8767.0 |
| CNOT3 | -8991.0 |
| CSNK1D | -9021.0 |
| TFB1M | -9093.0 |
| SRRM2 | -9273.0 |
| TRMT44 | -9398.0 |
| SNRNP200 | -9564.0 |
| POP4 | -9863.0 |
| SART1 | -9944.0 |
| CHERP | -10004.0 |
| AKT1 | -10034.0 |
| DDX41 | -10063.0 |
| APOBEC3H | -10550.0 |
| EDC4 | -10610.0 |
| PSMB11 | -10657.0 |
| RPL3L | -10862.0 |
| POLR2J | -10901.0 |
| TBL3 | -10912.0 |
| RPL10L | -10981.0 |
REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION
| 1161 | |
|---|---|
| set | REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION |
| setSize | 1336 |
| pANOVA | 5.37e-21 |
| s.dist | 0.153 |
| p.adjustANOVA | 2.94e-18 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RGCC | 10605 |
| MIR27A | 10554 |
| MIR24-2 | 10459 |
| ZNF737 | 10451 |
| FASLG | 10446 |
| BTG1 | 10442 |
| CDKN2B | 10441 |
| ZNF658 | 10374 |
| ZNF614 | 10364 |
| UCMA | 10317 |
| UBB | 10269 |
| RFFL | 10266 |
| PERP | 10250 |
| ZNF626 | 10211 |
| ZNF595 | 10170 |
| H3C12 | 10132 |
| ZNF155 | 10093 |
| CDK4 | 10023 |
| ZNF790 | 10021 |
| NPY | 9999 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RGCC | 10605.0 |
| MIR27A | 10554.0 |
| MIR24-2 | 10459.0 |
| ZNF737 | 10451.0 |
| FASLG | 10446.0 |
| BTG1 | 10442.0 |
| CDKN2B | 10441.0 |
| ZNF658 | 10374.0 |
| ZNF614 | 10364.0 |
| UCMA | 10317.0 |
| UBB | 10269.0 |
| RFFL | 10266.0 |
| PERP | 10250.0 |
| ZNF626 | 10211.0 |
| ZNF595 | 10170.0 |
| H3C12 | 10132.0 |
| ZNF155 | 10093.0 |
| CDK4 | 10023.0 |
| ZNF790 | 10021.0 |
| NPY | 9999.0 |
| COX6A1 | 9998.0 |
| SOD2 | 9985.0 |
| ZKSCAN4 | 9977.0 |
| HES1 | 9969.0 |
| GADD45A | 9959.0 |
| ZNF70 | 9953.0 |
| PIP4P1 | 9926.0 |
| ZNF17 | 9918.0 |
| ZNF211 | 9900.0 |
| ZNF440 | 9897.0 |
| ZNF749 | 9887.0 |
| BGLAP | 9886.0 |
| ZNF214 | 9881.0 |
| ZNF546 | 9876.0 |
| ZNF442 | 9845.0 |
| NDUFA4 | 9820.0 |
| JUNB | 9792.0 |
| RFC4 | 9786.0 |
| SRSF1 | 9784.0 |
| PVALB | 9778.0 |
| TBP | 9764.0 |
| CYCS | 9761.0 |
| GTF2H3 | 9734.0 |
| TPX2 | 9729.0 |
| ZNF300 | 9722.0 |
| SNRPF | 9718.0 |
| SPP1 | 9714.0 |
| ZNF860 | 9685.0 |
| ZNF460 | 9677.0 |
| RNU4ATAC | 9670.0 |
| SKIC8 | 9652.0 |
| ZNF225 | 9648.0 |
| G6PC1 | 9634.0 |
| ZNF701 | 9605.0 |
| RPA2 | 9599.0 |
| BTG2 | 9571.0 |
| ZNF420 | 9562.0 |
| ZNF37A | 9521.0 |
| LMO2 | 9518.0 |
| AURKB | 9516.0 |
| ZNF415 | 9515.0 |
| CCNG2 | 9451.0 |
| RBBP5 | 9443.0 |
| H2BC14 | 9436.0 |
| ZNF736 | 9427.0 |
| H4C8 | 9408.0 |
| RAD1 | 9403.0 |
| COX16 | 9398.0 |
| ZNF799 | 9357.0 |
| TTC5 | 9352.0 |
| ZNF350 | 9346.0 |
| ZNF596 | 9322.0 |
| ZNF717 | 9316.0 |
| PRDM7 | 9311.0 |
| ZNF273 | 9310.0 |
| H2AC14 | 9305.0 |
| KAT5 | 9291.0 |
| ZNF439 | 9286.0 |
| PSMB3 | 9282.0 |
| ZNF607 | 9281.0 |
| ZNF703 | 9273.0 |
| NPAS4 | 9262.0 |
| H2BC17 | 9247.0 |
| TAF13 | 9240.0 |
| H3-3A | 9239.0 |
| NABP1 | 9235.0 |
| ZNF624 | 9213.0 |
| RETN | 9205.0 |
| ZKSCAN8 | 9178.0 |
| RNU12 | 9177.0 |
| RABGGTB | 9169.0 |
| KIT | 9122.0 |
| H3C3 | 9111.0 |
| CTLA4 | 9094.0 |
| RBM8A | 9093.0 |
| PSMA6 | 9088.0 |
| GATA2 | 9063.0 |
| CITED2 | 9037.0 |
| LAMTOR2 | 9029.0 |
| PPP1R13L | 9024.0 |
| SP7 | 9008.0 |
| ZNF112 | 8994.0 |
| ZNF77 | 8981.0 |
| E2F5 | 8969.0 |
| PRELID1 | 8963.0 |
| ZNF577 | 8959.0 |
| PSMA7 | 8947.0 |
| DDIT4 | 8915.0 |
| H2AZ1 | 8894.0 |
| ZFP30 | 8890.0 |
| NR4A3 | 8876.0 |
| ZNF793 | 8847.0 |
| GTF2E1 | 8805.0 |
| POLR2L | 8803.0 |
| AGO1 | 8794.0 |
| CHEK2 | 8765.0 |
| ZNF680 | 8757.0 |
| PF4 | 8744.0 |
| ZNF560 | 8739.0 |
| PSME2 | 8738.0 |
| ITGA4 | 8730.0 |
| TAF9 | 8727.0 |
| ZNF418 | 8718.0 |
| EAF2 | 8701.0 |
| LAMTOR4 | 8697.0 |
| PSMC5 | 8695.0 |
| UBC | 8680.0 |
| PSMA1 | 8676.0 |
| BRD2 | 8657.0 |
| H2BC5 | 8646.0 |
| RBL1 | 8623.0 |
| DDIT3 | 8615.0 |
| SERPINB13 | 8574.0 |
| SCO1 | 8569.0 |
| CTSV | 8563.0 |
| MAPK14 | 8531.0 |
| POLR2D | 8521.0 |
| POLR2C | 8482.0 |
| ELF1 | 8469.0 |
| TAF15 | 8468.0 |
| ZNF597 | 8436.0 |
| TWIST1 | 8417.0 |
| YWHAH | 8406.0 |
| ZNF761 | 8403.0 |
| ANAPC16 | 8396.0 |
| SKP2 | 8386.0 |
| ZFP69B | 8382.0 |
| H4C4 | 8378.0 |
| PSMD12 | 8377.0 |
| TBX5 | 8372.0 |
| CEBPB | 8342.0 |
| ZNF304 | 8330.0 |
| ELL3 | 8328.0 |
| ZNF222 | 8320.0 |
| ZNF473 | 8246.0 |
| CAV1 | 8242.0 |
| CNOT11 | 8234.0 |
| MED4 | 8228.0 |
| CSTF2T | 8207.0 |
| IGFBP3 | 8178.0 |
| ZNF334 | 8177.0 |
| MED7 | 8176.0 |
| ZNF791 | 8171.0 |
| SRSF6 | 8166.0 |
| PSMB1 | 8157.0 |
| MYB | 8134.0 |
| FOXG1 | 8133.0 |
| CDC40 | 8132.0 |
| MYC | 8099.0 |
| SST | 8093.0 |
| RNMT | 8078.0 |
| ZNF670 | 8073.0 |
| JUN | 8056.0 |
| RBM14 | 8043.0 |
| PSMC4 | 8042.0 |
| LDB1 | 8039.0 |
| GPS2 | 8022.0 |
| OCLN | 7998.0 |
| GATA4 | 7988.0 |
| ZNF727 | 7983.0 |
| H2BC4 | 7968.0 |
| RSPO3 | 7962.0 |
| PAF1 | 7923.0 |
| SP1 | 7917.0 |
| TAF6 | 7909.0 |
| ZNF566 | 7902.0 |
| COX11 | 7898.0 |
| ACTL6A | 7882.0 |
| THOC1 | 7863.0 |
| IWS1 | 7853.0 |
| ZNF429 | 7802.0 |
| NAMPT | 7801.0 |
| MED20 | 7790.0 |
| ZNF551 | 7777.0 |
| ZNF490 | 7769.0 |
| CLP1 | 7758.0 |
| ZNF302 | 7753.0 |
| ZNF569 | 7751.0 |
| ZNF184 | 7740.0 |
| PCNA | 7690.0 |
| ZNF543 | 7675.0 |
| SNRPD3 | 7673.0 |
| POLR2I | 7672.0 |
| NR1D1 | 7664.0 |
| ZNF175 | 7658.0 |
| ZNF248 | 7626.0 |
| DLX5 | 7612.0 |
| MED31 | 7596.0 |
| TFAP2A | 7592.0 |
| IL2RA | 7578.0 |
| SIN3A | 7575.0 |
| ZNF547 | 7569.0 |
| ZNF688 | 7568.0 |
| CDK1 | 7556.0 |
| XPO1 | 7555.0 |
| ZNF470 | 7554.0 |
| MDM4 | 7548.0 |
| RYBP | 7527.0 |
| CDKN1B | 7523.0 |
| CTSL | 7520.0 |
| SMARCD2 | 7515.0 |
| ZNF660 | 7505.0 |
| ELOC | 7494.0 |
| SYT10 | 7489.0 |
| ZNF266 | 7488.0 |
| RORB | 7479.0 |
| GAD2 | 7476.0 |
| SARNP | 7472.0 |
| CDK5 | 7466.0 |
| PITX2 | 7458.0 |
| RNU11 | 7418.0 |
| THRA | 7414.0 |
| COX5A | 7405.0 |
| LAMTOR5 | 7399.0 |
| POU4F2 | 7397.0 |
| INTS7 | 7394.0 |
| ZNF782 | 7387.0 |
| ATXN3 | 7386.0 |
| ZNF215 | 7381.0 |
| SOX9 | 7376.0 |
| ATF2 | 7358.0 |
| PAPOLA | 7352.0 |
| L3MBTL1 | 7350.0 |
| GATAD2B | 7334.0 |
| POLR2H | 7324.0 |
| ZNF554 | 7322.0 |
| ZNF671 | 7285.0 |
| ZNF716 | 7265.0 |
| SYMPK | 7264.0 |
| H2AC18 | 7261.5 |
| H2AC19 | 7261.5 |
| ANAPC10 | 7259.0 |
| ZNF565 | 7232.0 |
| ZNF585A | 7230.0 |
| TP53RK | 7228.0 |
| BCL2L14 | 7225.0 |
| PSMB9 | 7201.0 |
| RAD17 | 7183.0 |
| ZNF136 | 7143.0 |
| TACO1 | 7132.0 |
| COX6B1 | 7125.0 |
| ARNT | 7111.0 |
| ZNF233 | 7101.0 |
| ZNF267 | 7049.0 |
| H2AC6 | 7006.0 |
| CDC26 | 6989.0 |
| MIR137 | 6960.0 |
| MED17 | 6937.0 |
| MED25 | 6908.0 |
| THOC6 | 6907.0 |
| UBA52 | 6901.0 |
| ZNF770 | 6883.0 |
| ZNF564 | 6865.0 |
| APOE | 6838.0 |
| EPC1 | 6823.0 |
| SOX2 | 6818.0 |
| SMARCE1 | 6817.0 |
| ANAPC1 | 6773.0 |
| H2BC15 | 6756.0 |
| H4C3 | 6755.0 |
| MED13 | 6753.0 |
| ZNF684 | 6714.0 |
| RNF2 | 6706.0 |
| H2BC9 | 6696.5 |
| H3C7 | 6696.5 |
| PTPN11 | 6694.0 |
| RNF34 | 6691.0 |
| FYTTD1 | 6681.0 |
| ZNF485 | 6674.0 |
| ZNF468 | 6673.0 |
| ZNF189 | 6661.0 |
| TGIF1 | 6659.0 |
| SNW1 | 6642.0 |
| SMAD4 | 6630.0 |
| TFAP2D | 6625.0 |
| ZNF679 | 6610.0 |
| ESR2 | 6607.0 |
| TNRC6B | 6600.0 |
| AURKA | 6597.0 |
| PCK1 | 6595.0 |
| H2AC4 | 6574.0 |
| BNIP3L | 6571.0 |
| GPAM | 6562.0 |
| ZNF234 | 6542.0 |
| HIPK1 | 6535.0 |
| TXNIP | 6528.0 |
| ZNF599 | 6525.0 |
| MED24 | 6503.0 |
| NR2E1 | 6479.0 |
| H2AZ2 | 6477.0 |
| NR1H3 | 6466.0 |
| PRDM1 | 6457.0 |
| H4C5 | 6455.0 |
| CBX3 | 6445.0 |
| YEATS4 | 6439.0 |
| ZNF562 | 6396.0 |
| ZNF101 | 6378.0 |
| ZNF561 | 6299.0 |
| TCEA1 | 6293.0 |
| SKIL | 6284.0 |
| PSMB7 | 6283.0 |
| INTS12 | 6272.0 |
| SUPT6H | 6269.0 |
| NKX3-2 | 6259.0 |
| NDRG1 | 6255.0 |
| PPM1D | 6247.0 |
| ZNF254 | 6243.0 |
| PGR | 6231.0 |
| RPS27A | 6223.0 |
| PSMB10 | 6211.0 |
| ZNF433 | 6178.0 |
| CDC25C | 6173.0 |
| GAD1 | 6156.0 |
| ZNF180 | 6153.0 |
| GRIN2A | 6127.0 |
| CDK2 | 6121.0 |
| ZNF584 | 6113.0 |
| COX7A2L | 6108.0 |
| POMC | 6091.0 |
| SNAPC5 | 6079.0 |
| MGA | 6077.0 |
| SESN3 | 6074.0 |
| ZNF582 | 6062.0 |
| FBXW7 | 6061.0 |
| MED30 | 6050.0 |
| ZNF337 | 6046.0 |
| ZNF230 | 6040.0 |
| YWHAZ | 6039.0 |
| POLR2E | 6038.0 |
| CNOT9 | 6037.0 |
| ZNF718 | 6034.0 |
| ZNF223 | 6024.0 |
| FOS | 6017.0 |
| CSTF1 | 6015.0 |
| PSMB8 | 6003.0 |
| E2F6 | 5989.0 |
| NLRC4 | 5974.0 |
| RBBP8 | 5966.0 |
| LSM11 | 5952.0 |
| ZNF655 | 5948.0 |
| SUPT16H | 5947.0 |
| PSMD13 | 5916.0 |
| DAXX | 5912.0 |
| RBBP4 | 5906.0 |
| ATAD2 | 5898.0 |
| ZNF285 | 5839.0 |
| TAF7 | 5814.0 |
| E2F7 | 5796.0 |
| TNFRSF10D | 5780.0 |
| TRIM63 | 5776.0 |
| CDKN2A | 5761.0 |
| TRIAP1 | 5757.0 |
| ZNF224 | 5749.0 |
| PCF11 | 5722.0 |
| SCO2 | 5680.0 |
| APAF1 | 5672.0 |
| ZNF100 | 5661.0 |
| TRPC3 | 5660.0 |
| ZNF14 | 5652.0 |
| CPSF2 | 5646.0 |
| KLF4 | 5644.0 |
| EXO1 | 5642.0 |
| CSNK2B | 5641.0 |
| EED | 5630.0 |
| CCNH | 5625.0 |
| LEF1 | 5565.0 |
| TAF11 | 5531.0 |
| ZNF555 | 5504.0 |
| ZNF785 | 5477.0 |
| ZNF431 | 5452.0 |
| NABP2 | 5446.0 |
| TNFRSF10A | 5444.0 |
| ZNF33A | 5430.0 |
| NR3C1 | 5426.0 |
| PSMC6 | 5420.0 |
| ICE2 | 5401.0 |
| PRKCQ | 5380.0 |
| ZNF714 | 5379.0 |
| SKP1 | 5377.0 |
| POLR2K | 5369.0 |
| CDK13 | 5362.0 |
| TP53INP1 | 5360.0 |
| HDAC3 | 5330.0 |
| JAG1 | 5302.0 |
| ZNF441 | 5293.0 |
| ZNF454 | 5281.0 |
| ZNF212 | 5262.0 |
| RPAP2 | 5260.0 |
| ASH2L | 5250.0 |
| ZNF627 | 5244.0 |
| BRCA1 | 5239.0 |
| RRM2B | 5203.0 |
| CDK5R1 | 5195.0 |
| INTS14 | 5192.0 |
| COX6C | 5172.0 |
| ZNF419 | 5160.0 |
| ZNF625 | 5143.0 |
| SUPT5H | 5131.0 |
| ESRRG | 5127.0 |
| UBE2D3 | 5120.0 |
| RPA3 | 5112.0 |
| PHC3 | 5054.0 |
| ZNF197 | 5051.0 |
| ZNF669 | 5033.0 |
| RARB | 5030.0 |
| H2BC3 | 5022.0 |
| TAF5 | 4981.0 |
| CDK8 | 4978.0 |
| ZNF143 | 4967.0 |
| PSMA4 | 4963.0 |
| ZNF141 | 4954.0 |
| PSMD7 | 4932.0 |
| TAF12 | 4927.0 |
| CCNB1 | 4895.0 |
| MED6 | 4888.0 |
| ICE1 | 4887.0 |
| COX4I1 | 4877.0 |
| MEF2C | 4874.0 |
| ZNF549 | 4865.0 |
| ABCA6 | 4861.0 |
| ITGA5 | 4854.0 |
| H4C9 | 4853.0 |
| ZNF621 | 4852.0 |
| CTSK | 4849.0 |
| DDX39A | 4808.0 |
| CCND3 | 4789.0 |
| SMARCA2 | 4786.0 |
| ZNF540 | 4780.0 |
| NR2F6 | 4756.0 |
| PRMT5 | 4742.0 |
| ZNF839 | 4730.0 |
| SERPINE1 | 4724.0 |
| H4C16 | 4688.0 |
| ZNF583 | 4676.0 |
| RPRD2 | 4675.0 |
| H2AJ | 4666.0 |
| ZNF250 | 4665.0 |
| ZNF709 | 4645.0 |
| ZNF649 | 4635.0 |
| BDNF | 4628.0 |
| ZIM2 | 4610.0 |
| NCBP1 | 4593.0 |
| MRE11 | 4573.0 |
| H2BC6 | 4552.0 |
| RUNX2 | 4542.0 |
| BMI1 | 4535.0 |
| SLC2A3 | 4513.0 |
| ITCH | 4511.0 |
| E2F8 | 4470.0 |
| ZNF461 | 4447.0 |
| MLH1 | 4436.0 |
| PARP1 | 4427.0 |
| ZNF227 | 4400.0 |
| ZNF570 | 4390.0 |
| ZNF875 | 4381.0 |
| ZNF74 | 4351.0 |
| MYBL2 | 4319.0 |
| ZNF563 | 4312.0 |
| THOC5 | 4309.0 |
| ELOB | 4304.0 |
| H4C2 | 4300.0 |
| ZNF521 | 4275.0 |
| ZNF571 | 4264.0 |
| INTS8 | 4224.0 |
| ZNF343 | 4215.0 |
| PMAIP1 | 4202.0 |
| CBX5 | 4185.0 |
| TCF7L1 | 4143.0 |
| TIGAR | 4127.0 |
| ZNF668 | 4126.0 |
| PSMA3 | 4116.0 |
| SRSF2 | 4105.0 |
| SNAPC1 | 4091.0 |
| GTF2E2 | 4090.0 |
| PIP4K2A | 4026.0 |
| H4C6 | 4018.0 |
| GSK3B | 4006.0 |
| MAML2 | 3993.0 |
| RHNO1 | 3991.0 |
| ZNF324B | 3980.0 |
| ZNF20 | 3971.0 |
| SMAD1 | 3967.0 |
| IL6 | 3948.0 |
| ZNF479 | 3946.0 |
| PPARG | 3943.0 |
| KMT2A | 3940.0 |
| SUZ12 | 3929.0 |
| CDC73 | 3913.0 |
| RBX1 | 3880.0 |
| SIRT3 | 3874.0 |
| PTPN1 | 3865.0 |
| CAMK4 | 3863.0 |
| ZNF99 | 3834.0 |
| PTEN | 3814.0 |
| FANCD2 | 3790.0 |
| IGFBP1 | 3785.0 |
| ZNF552 | 3771.0 |
| SRSF3 | 3757.0 |
| INTS9 | 3756.0 |
| CPSF6 | 3738.0 |
| OPRM1 | 3725.0 |
| HDAC9 | 3675.0 |
| H2BC12 | 3661.0 |
| ZNF486 | 3653.0 |
| NR1I2 | 3647.0 |
| ZFP69 | 3643.0 |
| REST | 3638.0 |
| PRELID3A | 3629.0 |
| ESRRA | 3617.0 |
| L3MBTL2 | 3605.0 |
| BBC3 | 3585.0 |
| PCGF5 | 3566.0 |
| GTF2H4 | 3554.0 |
| RFC2 | 3550.0 |
| ATM | 3539.0 |
| NR2C2AP | 3533.0 |
| ZNF573 | 3525.0 |
| NPM1 | 3501.0 |
| CCNA1 | 3453.0 |
| NFYB | 3373.0 |
| ZNF510 | 3368.0 |
| ZNF665 | 3350.0 |
| PSMB2 | 3326.0 |
| CPSF3 | 3298.0 |
| ZNF333 | 3282.0 |
| ZNF721 | 3277.0 |
| H2AC20 | 3275.0 |
| ZNF713 | 3273.0 |
| RARG | 3261.0 |
| ZNF616 | 3253.0 |
| MDC1 | 3251.0 |
| POU2F2 | 3249.0 |
| SRF | 3235.0 |
| ATR | 3230.0 |
| ZNF613 | 3188.0 |
| GRIA2 | 3186.0 |
| CCNK | 3169.0 |
| POLDIP3 | 3152.0 |
| SPI1 | 3112.0 |
| ZNF320 | 3074.0 |
| YAP1 | 3070.0 |
| SESN1 | 3069.0 |
| ING2 | 3059.0 |
| PSMB4 | 3049.0 |
| TNFRSF10C | 3048.0 |
| PRKAA1 | 3011.0 |
| TBL1XR1 | 3008.0 |
| PSMC1 | 2987.0 |
| ZNF436 | 2978.0 |
| H3C2 | 2976.0 |
| CRADD | 2959.0 |
| GTF2H5 | 2954.0 |
| ZNF697 | 2938.0 |
| ZNF729 | 2935.0 |
| ZNF696 | 2929.0 |
| WDR33 | 2922.0 |
| PRKAB2 | 2894.0 |
| ZNF492 | 2810.0 |
| HAND2 | 2787.0 |
| RNF111 | 2782.0 |
| CCND2 | 2780.0 |
| NRBF2 | 2775.0 |
| ZNF253 | 2773.0 |
| WRN | 2771.0 |
| INTS13 | 2767.0 |
| ALYREF | 2764.0 |
| CAT | 2753.0 |
| TGFA | 2746.0 |
| SMARCD1 | 2741.0 |
| NKX2-5 | 2730.0 |
| ELF2 | 2723.0 |
| ZNF776 | 2722.0 |
| ZNF771 | 2710.0 |
| ANAPC15 | 2703.0 |
| U2AF1L4 | 2692.0 |
| YWHAG | 2674.0 |
| COX18 | 2659.0 |
| ZNF530 | 2628.0 |
| ZNF3 | 2620.0 |
| NUDT21 | 2618.0 |
| RBPJ | 2594.0 |
| RAD9B | 2575.0 |
| CUL1 | 2567.0 |
| SSRP1 | 2557.0 |
| ZNF620 | 2553.0 |
| PINK1 | 2551.0 |
| UBE2S | 2530.0 |
| ZNF28 | 2525.0 |
| TXN | 2519.0 |
| CCNT2 | 2512.0 |
| H2BC11 | 2506.0 |
| HDAC2 | 2488.0 |
| SRSF11 | 2478.0 |
| CDK6 | 2462.0 |
| TNFRSF10B | 2459.0 |
| ZNF263 | 2458.0 |
| MNAT1 | 2449.0 |
| ZNF559 | 2447.0 |
| MED23 | 2444.0 |
| GTF2H1 | 2440.0 |
| ZC3H8 | 2423.0 |
| ZNF514 | 2417.0 |
| YWHAE | 2415.0 |
| BLM | 2402.0 |
| PSMA8 | 2379.0 |
| JMY | 2330.0 |
| ZNF548 | 2327.0 |
| CDC27 | 2297.0 |
| CNOT6L | 2292.0 |
| ELOA2 | 2265.0 |
| TOP3A | 2260.0 |
| CSTF3 | 2236.0 |
| ELOA | 2222.0 |
| ZNF169 | 2216.0 |
| ZNF398 | 2183.0 |
| MAML1 | 2175.0 |
| PSMD1 | 2144.0 |
| POLR2G | 2138.0 |
| MAPK1 | 2130.0 |
| PSME4 | 2128.0 |
| SRRM1 | 2110.0 |
| BAX | 2092.0 |
| COX20 | 2082.0 |
| RORC | 2081.0 |
| PSMB5 | 2078.0 |
| FOXO1 | 2055.0 |
| CNOT2 | 2047.0 |
| ZNF774 | 2034.0 |
| ZNF43 | 2021.0 |
| ZNF430 | 1991.0 |
| RRAGC | 1990.0 |
| POU2F1 | 1960.0 |
| RMI2 | 1950.0 |
| SLBP | 1943.0 |
| CRH | 1930.0 |
| INTS6 | 1916.0 |
| CDC23 | 1913.0 |
| RRAGA | 1886.0 |
| ZNF235 | 1881.0 |
| SOCS4 | 1869.0 |
| ZNF529 | 1864.0 |
| CNOT8 | 1860.0 |
| ZNF140 | 1848.0 |
| INTS4 | 1820.0 |
| TFAP2B | 1779.0 |
| ZNF692 | 1778.0 |
| MAGOH | 1757.0 |
| PSMC3 | 1749.0 |
| ITGA2B | 1745.0 |
| RRAGD | 1739.0 |
| RXRG | 1733.0 |
| H2BC21 | 1717.0 |
| SRSF7 | 1680.0 |
| SEM1 | 1657.0 |
| PSMC2 | 1653.0 |
| ZNF274 | 1652.0 |
| PRKAG1 | 1650.0 |
| ZNF354A | 1620.0 |
| CREB1 | 1614.0 |
| ZNF682 | 1589.0 |
| CBX4 | 1588.0 |
| GLS2 | 1585.0 |
| ZNF606 | 1575.0 |
| HEY1 | 1561.0 |
| NCBP2 | 1556.0 |
| HSPD1 | 1551.0 |
| ANAPC5 | 1528.0 |
| CASC3 | 1522.0 |
| BRIP1 | 1521.0 |
| CCNT1 | 1512.0 |
| BID | 1506.0 |
| ARID1A | 1466.0 |
| E2F1 | 1406.0 |
| PSMD4 | 1403.0 |
| CNOT7 | 1393.0 |
| NR1H2 | 1375.0 |
| ZNF772 | 1317.0 |
| SETD9 | 1305.0 |
| THRB | 1304.0 |
| ZNF268 | 1288.0 |
| ANAPC7 | 1287.0 |
| SATB2 | 1276.0 |
| FAS | 1254.0 |
| PHC1 | 1236.0 |
| PIP4K2C | 1204.0 |
| ZNF610 | 1193.0 |
| LAMTOR3 | 1190.0 |
| ZNF226 | 1136.0 |
| TFAP2C | 1125.0 |
| RNPS1 | 1122.0 |
| PRKAG3 | 1111.0 |
| ZNF700 | 1098.0 |
| MIR132 | 1091.0 |
| CCND1 | 1077.0 |
| ZNF394 | 1068.0 |
| ZNF213 | 1066.0 |
| SNRPE | 1062.0 |
| MET | 1042.0 |
| TRIM28 | 1038.0 |
| ZNF257 | 1031.0 |
| MLLT3 | 1024.0 |
| NFE2 | 1012.0 |
| MAML3 | 1009.0 |
| ZKSCAN5 | 1004.0 |
| ZNF730 | 991.0 |
| UBE2E1 | 974.0 |
| RORA | 967.0 |
| NR5A2 | 953.0 |
| ZNF19 | 938.0 |
| HNF4G | 928.0 |
| ZNF773 | 920.0 |
| CDK7 | 909.0 |
| ZNF585B | 906.0 |
| YAF2 | 894.0 |
| ZNF443 | 861.0 |
| MSH2 | 838.0 |
| TP53 | 830.0 |
| ZNF264 | 821.0 |
| ZSCAN32 | 816.0 |
| RAD50 | 807.0 |
| RFC5 | 799.0 |
| ZNF493 | 794.0 |
| H2AX | 764.0 |
| FBXO32 | 760.0 |
| KDM5B | 750.0 |
| TAF3 | 739.0 |
| ZNF45 | 701.0 |
| MAPKAPK5 | 691.0 |
| PPARGC1B | 675.0 |
| PSMA5 | 665.0 |
| SUPT4H1 | 630.0 |
| NFYA | 629.0 |
| LIFR | 611.0 |
| H3C11 | 608.0 |
| ABL1 | 607.0 |
| ZNF30 | 604.0 |
| ZNF432 | 598.0 |
| GATAD2A | 595.0 |
| ZNF764 | 582.0 |
| DDB2 | 576.0 |
| NCOR1 | 549.0 |
| RBFOX1 | 545.0 |
| MDM2 | 542.0 |
| ZNF641 | 540.0 |
| COX5B | 536.0 |
| CCNA2 | 521.0 |
| TP53I3 | 519.0 |
| PSMA2 | 467.0 |
| ZNF792 | 462.0 |
| CDK12 | 461.0 |
| ZNF287 | 453.0 |
| KAT2B | 408.0 |
| EZH2 | 400.0 |
| COX8A | 395.0 |
| ZNF354C | 374.0 |
| CCNE2 | 369.0 |
| MMP13 | 343.0 |
| ZNF221 | 338.0 |
| ACTL6B | 330.0 |
| ZNF786 | 326.0 |
| TXNRD1 | 306.0 |
| EAF1 | 299.0 |
| RFC3 | 297.0 |
| GTF2B | 289.0 |
| PSMD3 | 274.0 |
| ZNF677 | 271.0 |
| COX19 | 256.0 |
| ZNF416 | 241.0 |
| BRD7 | 210.0 |
| CASP6 | 201.0 |
| ZNF286A | 189.0 |
| ZNF25 | 179.0 |
| PPP2R1A | 156.0 |
| ZNF724 | 155.0 |
| DEK | 132.0 |
| TAF8 | 129.0 |
| ESR1 | 113.0 |
| NR3C2 | 97.0 |
| MSX2 | 95.0 |
| ZC3H11A | 85.0 |
| AGO3 | 75.0 |
| NR1D2 | 69.0 |
| SRSF5 | 65.0 |
| ZNF615 | 51.0 |
| YBX1 | 28.0 |
| ZNF195 | 23.0 |
| NFKB1 | 12.0 |
| CTR9 | -1.0 |
| ERBB2 | -16.0 |
| DLX6 | -31.0 |
| MEAF6 | -34.0 |
| HDAC10 | -42.0 |
| ZNF567 | -62.0 |
| H4C1 | -64.0 |
| RPA1 | -66.0 |
| NR1I3 | -68.0 |
| ZIK1 | -82.0 |
| ZNF2 | -102.0 |
| ANAPC11 | -133.0 |
| INTS10 | -140.0 |
| NELFB | -143.0 |
| RB1 | -156.0 |
| ZNF500 | -165.0 |
| H3C6 | -174.0 |
| ITGAL | -179.0 |
| PRKCB | -186.0 |
| ZNF747 | -187.0 |
| PSMD14 | -192.0 |
| ZNF202 | -220.0 |
| RARA | -226.0 |
| MED15 | -238.0 |
| SMAD7 | -244.0 |
| TNFRSF18 | -247.0 |
| INTS5 | -270.0 |
| TCF12 | -294.0 |
| KMT5A | -305.0 |
| NR2F1 | -315.0 |
| NR2C1 | -332.0 |
| GAMT | -342.0 |
| CR1 | -352.0 |
| ZNF256 | -397.0 |
| SNAPC2 | -407.0 |
| CSNK2A1 | -415.0 |
| NFYC | -421.0 |
| ZNF446 | -425.0 |
| AUTS2 | -471.0 |
| MTA2 | -511.0 |
| PRDX5 | -512.0 |
| PCGF6 | -568.0 |
| PSME3 | -576.0 |
| ZNF33B | -577.0 |
| WWTR1 | -588.0 |
| RHEB | -599.0 |
| HDAC11 | -615.0 |
| RTF1 | -623.0 |
| H2BC10 | -630.0 |
| NR6A1 | -655.0 |
| ZNF681 | -673.0 |
| PRMT6 | -683.0 |
| MAGOHB | -712.0 |
| UBE2C | -737.0 |
| ZNF689 | -740.0 |
| USP2 | -780.0 |
| ZNF726 | -784.0 |
| NR4A2 | -788.0 |
| LSM10 | -794.0 |
| CNOT1 | -819.0 |
| PML | -830.0 |
| STAT1 | -837.0 |
| PSME1 | -840.0 |
| CHEK1 | -886.0 |
| TCF7 | -890.0 |
| TFDP2 | -949.0 |
| DYRK2 | -962.0 |
| MAPKAP1 | -985.0 |
| ZKSCAN1 | -988.0 |
| INTS2 | -991.0 |
| ZNF732 | -1053.0 |
| H3C8 | -1062.0 |
| COX14 | -1067.0 |
| PSMD6 | -1076.0 |
| YWHAQ | -1078.0 |
| CASP10 | -1093.0 |
| PSMD11 | -1095.0 |
| PPM1A | -1112.0 |
| EP300 | -1121.0 |
| H4C13 | -1134.0 |
| TEAD4 | -1136.0 |
| TAF1L | -1149.0 |
| SESN2 | -1204.0 |
| CCNE1 | -1241.0 |
| PPP2CA | -1246.0 |
| CNOT4 | -1262.0 |
| BCL6 | -1281.0 |
| GPRIN1 | -1309.0 |
| RAD51D | -1340.0 |
| NR1H4 | -1354.0 |
| GLS | -1363.0 |
| ZNF471 | -1404.0 |
| RPRD1B | -1420.0 |
| ZNF484 | -1428.0 |
| KCTD15 | -1470.0 |
| TJP1 | -1476.0 |
| ZNF71 | -1483.0 |
| BCL2L11 | -1488.0 |
| ZNF311 | -1494.0 |
| NUAK1 | -1502.0 |
| CNOT10 | -1509.0 |
| ZNF200 | -1516.0 |
| ZNF92 | -1517.0 |
| ZNF568 | -1537.0 |
| ZNF138 | -1542.0 |
| ERCC3 | -1589.0 |
| PSMD5 | -1600.0 |
| ZNF34 | -1607.0 |
| H3-3B | -1628.0 |
| ZNF550 | -1631.0 |
| NELFE | -1661.0 |
| CGA | -1675.0 |
| ZKSCAN3 | -1681.0 |
| YWHAB | -1708.0 |
| PSMD8 | -1715.0 |
| ANAPC4 | -1773.0 |
| MED26 | -1782.0 |
| GTF2F1 | -1794.0 |
| ZFP2 | -1798.0 |
| NOTCH2 | -1825.0 |
| PRDX2 | -1840.0 |
| CDC7 | -1848.0 |
| ARID2 | -1856.0 |
| CBFB | -1862.0 |
| NOP2 | -1886.0 |
| ZNF75A | -1893.0 |
| PSMD9 | -1897.0 |
| SNAPC3 | -1905.0 |
| ZNF557 | -1908.0 |
| H4C12 | -1933.0 |
| ELL2 | -1971.0 |
| GTF2A1 | -2018.0 |
| RPRD1A | -2023.0 |
| H3C1 | -2029.0 |
| WWP1 | -2088.0 |
| MED10 | -2115.0 |
| MED8 | -2127.0 |
| ZNF589 | -2128.0 |
| VEGFA | -2133.0 |
| TNRC6A | -2135.0 |
| ZNF79 | -2137.0 |
| ZNF804B | -2140.0 |
| DDX39B | -2196.0 |
| OPRK1 | -2227.0 |
| PPP2CB | -2234.0 |
| PLK2 | -2238.0 |
| GTF2A2 | -2258.0 |
| ZNF706 | -2261.0 |
| ZNF347 | -2262.0 |
| YY1 | -2274.0 |
| FANCI | -2276.0 |
| RMI1 | -2292.0 |
| CASP1 | -2295.0 |
| CAMK2D | -2329.0 |
| TEAD2 | -2368.0 |
| FOXO3 | -2372.0 |
| GLI3 | -2390.0 |
| GTF2F2 | -2395.0 |
| PPARGC1A | -2397.0 |
| LEO1 | -2404.0 |
| PHAX | -2405.0 |
| HEY2 | -2407.0 |
| CCN2 | -2466.0 |
| ZNF691 | -2488.0 |
| ZNF483 | -2494.0 |
| ZKSCAN7 | -2537.0 |
| BLK | -2543.0 |
| CDC16 | -2545.0 |
| KRBOX5 | -2578.0 |
| TGFB1 | -2596.0 |
| HNF4A | -2608.0 |
| CHD3 | -2612.0 |
| RAD51 | -2618.0 |
| SURF1 | -2649.0 |
| ZNF708 | -2664.0 |
| HDAC5 | -2709.0 |
| ZNF18 | -2720.0 |
| HUS1 | -2809.0 |
| CTNNB1 | -2828.0 |
| ZFP1 | -2839.0 |
| PHF20 | -2859.0 |
| LAMTOR1 | -2877.0 |
| KAT6A | -2884.0 |
| ZNF662 | -2886.0 |
| PIN1 | -2906.0 |
| TAF10 | -2930.0 |
| ARNT2 | -2969.0 |
| PLAGL1 | -2997.0 |
| PPP2R5C | -3049.0 |
| TOPBP1 | -3051.0 |
| ZNF133 | -3056.0 |
| PAX5 | -3066.0 |
| CNOT6 | -3070.0 |
| RBFOX3 | -3074.0 |
| KCTD6 | -3108.0 |
| ZNF23 | -3120.0 |
| ZNF324 | -3171.0 |
| TEAD1 | -3225.0 |
| TP53BP2 | -3234.0 |
| KCTD1 | -3257.0 |
| SGK1 | -3261.0 |
| ZNF746 | -3311.0 |
| LMO1 | -3313.0 |
| PCGF2 | -3322.0 |
| FKBP5 | -3355.0 |
| ZIM3 | -3372.0 |
| SMURF2 | -3392.0 |
| SCMH1 | -3398.0 |
| H2BC13 | -3416.0 |
| DPY30 | -3437.0 |
| KMT2C | -3441.0 |
| CALM1 | -3487.0 |
| ZNF586 | -3490.0 |
| IQSEC3 | -3492.0 |
| CDKN1A | -3505.0 |
| SUMO1 | -3519.0 |
| CSF1R | -3532.0 |
| USP7 | -3550.0 |
| GPI | -3564.0 |
| ZNF135 | -3572.0 |
| ZNF664 | -3581.0 |
| ZNF667 | -3589.0 |
| PRDX1 | -3592.0 |
| HIPK2 | -3625.0 |
| CENPJ | -3638.0 |
| ZNF160 | -3650.0 |
| VDR | -3664.0 |
| SMARCD3 | -3674.0 |
| POLR2B | -3675.0 |
| MOV10 | -3677.0 |
| RICTOR | -3706.0 |
| FANCC | -3711.0 |
| MEN1 | -3712.0 |
| RXRB | -3717.0 |
| ZFP28 | -3719.0 |
| ZFP90 | -3724.0 |
| TEAD3 | -3801.0 |
| TNKS1BP1 | -3825.0 |
| SMARCC1 | -3856.0 |
| TP73 | -3862.0 |
| LRPPRC | -3867.0 |
| SNRPG | -3880.0 |
| RUNX3 | -3882.0 |
| ZNF154 | -3891.0 |
| ZNF611 | -3894.0 |
| ARID3A | -3925.0 |
| ZNF704 | -3940.0 |
| LBR | -3946.0 |
| DLL1 | -3998.0 |
| GSR | -4001.0 |
| PRMT1 | -4014.0 |
| RBL2 | -4030.0 |
| PLXNA4 | -4031.0 |
| ZNF10 | -4134.0 |
| BRPF3 | -4145.0 |
| CAMK2B | -4174.0 |
| PSMF1 | -4178.0 |
| H3C4 | -4187.0 |
| CSNK2A2 | -4208.0 |
| H2AC7 | -4211.0 |
| H2BC7 | -4211.0 |
| TCF7L2 | -4223.0 |
| MAPK11 | -4242.0 |
| H2AC8 | -4264.0 |
| FIP1L1 | -4270.0 |
| ARID1B | -4282.0 |
| PPP1R13B | -4319.0 |
| SIRT1 | -4337.0 |
| SMAD6 | -4341.0 |
| ZNF114 | -4347.0 |
| SMYD2 | -4374.0 |
| CCNC | -4390.0 |
| PBRM1 | -4407.0 |
| TFAP2E | -4419.0 |
| ZNF208 | -4422.0 |
| DNA2 | -4453.0 |
| PABPN1 | -4462.0 |
| RNGTT | -4464.0 |
| NRBP1 | -4514.0 |
| SLC38A9 | -4527.0 |
| GRIN2B | -4542.0 |
| POU4F1 | -4543.0 |
| TRIM33 | -4554.0 |
| CASP2 | -4596.0 |
| IHH | -4684.0 |
| YES1 | -4728.0 |
| ZNF317 | -4794.0 |
| NBN | -4811.0 |
| NOTCH4 | -4823.0 |
| STEAP3 | -4862.0 |
| TAF4B | -4863.0 |
| TAL1 | -4896.0 |
| SOCS3 | -4897.0 |
| SRSF4 | -4901.0 |
| ZNF707 | -4964.0 |
| ZSCAN25 | -4965.0 |
| ZNF556 | -4970.0 |
| SKI | -5013.0 |
| H2BC8 | -5026.0 |
| ZFHX3 | -5034.0 |
| CDK9 | -5042.0 |
| ZNF710 | -5051.0 |
| AKT3 | -5060.0 |
| INTS3 | -5065.0 |
| DHX38 | -5092.0 |
| TNRC6C | -5100.0 |
| ZNF740 | -5171.0 |
| ZNF775 | -5182.0 |
| BMP2 | -5186.0 |
| ESRRB | -5190.0 |
| THBS1 | -5216.0 |
| RAD9A | -5227.0 |
| PHC2 | -5228.0 |
| ZNF544 | -5243.0 |
| TSC1 | -5245.0 |
| POLR2F | -5251.0 |
| ZNF26 | -5259.0 |
| CITED4 | -5270.0 |
| CAMK2G | -5275.0 |
| HDAC1 | -5289.0 |
| NFATC2 | -5296.0 |
| TP63 | -5308.0 |
| ZNF619 | -5342.0 |
| PSMB6 | -5356.0 |
| PLK3 | -5365.0 |
| SMURF1 | -5380.0 |
| AGO4 | -5477.0 |
| MAP2K6 | -5479.0 |
| NOTCH3 | -5482.0 |
| CBX2 | -5495.0 |
| RUNX1 | -5564.0 |
| WWOX | -5566.0 |
| THOC3 | -5567.0 |
| ZNF678 | -5590.0 |
| MOBP | -5591.0 |
| TMEM219 | -5621.0 |
| NPPA | -5632.0 |
| AFF4 | -5643.0 |
| PMS2 | -5663.0 |
| CCNG1 | -5669.0 |
| UBE2D1 | -5677.0 |
| ZNF382 | -5748.0 |
| SMAD2 | -5752.0 |
| ZNF205 | -5754.0 |
| ZNF528 | -5821.0 |
| ZNF417 | -5827.0 |
| BIRC5 | -5845.0 |
| ZNF517 | -5867.0 |
| TGIF2 | -5887.0 |
| KRAS | -5915.0 |
| THOC7 | -5923.0 |
| PDPK1 | -5927.0 |
| TWIST2 | -5948.0 |
| MLLT1 | -5987.0 |
| RELA | -6000.0 |
| SIN3B | -6003.0 |
| ZNF426 | -6012.0 |
| HDAC7 | -6073.0 |
| RING1 | -6082.0 |
| COL1A1 | -6090.0 |
| BARD1 | -6121.0 |
| CAMK2A | -6130.0 |
| SETD1B | -6131.0 |
| PSMD2 | -6144.0 |
| PRKACA | -6164.0 |
| VENTX | -6197.0 |
| SLU7 | -6202.0 |
| ITGBL1 | -6241.0 |
| MED16 | -6250.0 |
| ZNF496 | -6299.0 |
| CHTOP | -6317.0 |
| CHD4 | -6325.0 |
| MBD3 | -6330.0 |
| PRKAA2 | -6365.0 |
| ZNF605 | -6380.0 |
| SNRPB | -6416.0 |
| CBX6 | -6420.0 |
| ZNF778 | -6460.0 |
| MED1 | -6464.0 |
| NR2C2 | -6479.0 |
| CPSF7 | -6485.0 |
| ZNF425 | -6508.0 |
| PRKAG2 | -6509.0 |
| GEM | -6526.0 |
| NR5A1 | -6546.0 |
| RPTOR | -6584.0 |
| PIP4K2B | -6588.0 |
| PRR5 | -6598.0 |
| STK11 | -6604.0 |
| TAF2 | -6609.0 |
| BMAL1 | -6641.0 |
| KMT2E | -6657.0 |
| MAX | -6665.0 |
| ZNF331 | -6667.0 |
| SMARCC2 | -6753.0 |
| PTPN4 | -6759.0 |
| HTT | -6897.0 |
| E2F4 | -6907.0 |
| ZNF675 | -6929.0 |
| HIVEP3 | -6933.0 |
| PPP2R1B | -6960.0 |
| PPARD | -6978.0 |
| CPSF4 | -7119.0 |
| COX7C | -7158.0 |
| MED27 | -7170.0 |
| SMARCB1 | -7173.0 |
| NEDD4L | -7230.0 |
| MSTN | -7260.0 |
| ZFP14 | -7270.0 |
| KAT2A | -7275.0 |
| U2AF2 | -7309.0 |
| LGALS3 | -7326.0 |
| ELL | -7332.0 |
| EGFR | -7359.0 |
| PRKAB1 | -7414.0 |
| H2BC26 | -7437.0 |
| CLDN5 | -7457.0 |
| SMAD3 | -7487.0 |
| ZNF480 | -7488.0 |
| BRD1 | -7492.0 |
| KMT2B | -7511.0 |
| ZNF587 | -7554.0 |
| CPSF1 | -7597.0 |
| SETD1A | -7624.0 |
| EHMT2 | -7650.0 |
| MAF | -7692.0 |
| NELFA | -7695.0 |
| FURIN | -7705.0 |
| ZNF735 | -7750.0 |
| PPARA | -7755.0 |
| DGCR8 | -7776.0 |
| FZR1 | -7779.0 |
| UBE2I | -7784.0 |
| FOXO6 | -7807.0 |
| AGRP | -7838.0 |
| ZNF385A | -7865.0 |
| SREBF1 | -7888.0 |
| ZFP37 | -7923.0 |
| EHMT1 | -7943.0 |
| ZNF777 | -7995.0 |
| ZNF354B | -8001.0 |
| INTS11 | -8012.0 |
| ZNF124 | -8046.0 |
| ZNF600 | -8074.0 |
| H2BC1 | -8099.0 |
| ERCC2 | -8106.0 |
| RRM2 | -8159.0 |
| SRRT | -8192.0 |
| POLR2A | -8208.0 |
| CGB8 | -8213.0 |
| NELFCD | -8227.0 |
| SSU72 | -8247.0 |
| INS | -8268.0 |
| ZNF12 | -8282.0 |
| ZNF282 | -8295.0 |
| MLST8 | -8336.0 |
| CREBBP | -8338.0 |
| HDAC4 | -8342.0 |
| BANP | -8450.0 |
| KCNIP3 | -8452.0 |
| SRSF9 | -8494.0 |
| RABGGTA | -8555.0 |
| H3C10 | -8558.0 |
| STUB1 | -8577.0 |
| NR4A1 | -8578.0 |
| AGO2 | -8596.0 |
| KRBA1 | -8609.0 |
| COL1A2 | -8686.0 |
| SMARCA4 | -8689.0 |
| ZNF676 | -8696.0 |
| AXIN1 | -8754.0 |
| EIF4A3 | -8763.0 |
| AIFM2 | -8772.0 |
| SFN | -8815.0 |
| MTOR | -8832.0 |
| TFDP1 | -8835.0 |
| IFNG | -8861.0 |
| ZNF738 | -8883.0 |
| GATA3 | -8907.0 |
| PCBP4 | -8914.0 |
| MYL9 | -8976.0 |
| CNOT3 | -8991.0 |
| NCOR2 | -9014.0 |
| RXRA | -9025.0 |
| ZNF445 | -9071.0 |
| CSF2 | -9079.0 |
| ZNF506 | -9105.0 |
| GLI2 | -9115.0 |
| H4C11 | -9168.0 |
| SRC | -9360.0 |
| RET | -9370.0 |
| ING5 | -9498.0 |
| ATRIP | -9533.0 |
| ANAPC2 | -9561.0 |
| AKT2 | -9562.0 |
| GPX2 | -9576.0 |
| TSC2 | -9603.0 |
| BRPF1 | -9626.0 |
| NOTCH1 | -9691.0 |
| MIR24-1 | -9733.0 |
| ZNF519 | -9762.0 |
| MAPK3 | -9797.0 |
| CBX8 | -9809.0 |
| IL2 | -9826.0 |
| INTS1 | -9837.0 |
| ZFPM1 | -9899.0 |
| GCK | -9910.0 |
| CTDP1 | -9960.0 |
| TP53AIP1 | -9963.0 |
| AKT1 | -10034.0 |
| TCF3 | -10233.0 |
| CARM1 | -10282.0 |
| SNAPC4 | -10303.0 |
| TAF4 | -10304.0 |
| ZNF558 | -10311.0 |
| ZNF383 | -10349.0 |
| NR0B2 | -10387.0 |
| NR2E3 | -10392.0 |
| ZNF699 | -10393.0 |
| PIDD1 | -10424.0 |
| GP1BA | -10466.0 |
| IL3 | -10501.0 |
| ZNF750 | -10607.0 |
| PSMB11 | -10657.0 |
| NOC2L | -10676.0 |
| WDR5 | -10745.0 |
| POLR2J | -10901.0 |
| CGB5 | -11020.0 |
| KMT2D | -11066.0 |
REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE
| 271 | |
|---|---|
| set | REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE |
| setSize | 105 |
| pANOVA | 6.47e-15 |
| s.dist | 0.44 |
| p.adjustANOVA | 2.66e-12 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL39L | 10429.0 |
| SEC61B | 10414.0 |
| RPLP1 | 10383.0 |
| RPL19 | 10237.0 |
| RPL27A | 10126.0 |
| RPL38 | 10097.0 |
| RPS12 | 10065.0 |
| RPL27 | 10018.0 |
| RPL12 | 9972.0 |
| RPL5 | 9847.0 |
| RPL10A | 9823.0 |
| RPSA | 9598.0 |
| RPL35A | 9504.0 |
| RPL13 | 9355.0 |
| SEC61G | 9264.0 |
| RPL11 | 9263.0 |
| RPL34 | 8949.0 |
| RPL36AL | 8546.5 |
| SRP54 | 8446.0 |
| RPL18A | 8433.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL39L | 10429.0 |
| SEC61B | 10414.0 |
| RPLP1 | 10383.0 |
| RPL19 | 10237.0 |
| RPL27A | 10126.0 |
| RPL38 | 10097.0 |
| RPS12 | 10065.0 |
| RPL27 | 10018.0 |
| RPL12 | 9972.0 |
| RPL5 | 9847.0 |
| RPL10A | 9823.0 |
| RPSA | 9598.0 |
| RPL35A | 9504.0 |
| RPL13 | 9355.0 |
| SEC61G | 9264.0 |
| RPL11 | 9263.0 |
| RPL34 | 8949.0 |
| RPL36AL | 8546.5 |
| SRP54 | 8446.0 |
| RPL18A | 8433.0 |
| RPS18 | 8418.0 |
| RPL7 | 8407.0 |
| RPS14 | 8367.0 |
| RPL37 | 8126.0 |
| SRP9 | 8055.0 |
| RPS28 | 8053.0 |
| RPL7A | 7958.0 |
| SPCS1 | 7856.0 |
| RPL23 | 7819.0 |
| SSR2 | 7799.0 |
| SEC11C | 7794.0 |
| SEC11A | 7606.0 |
| RPL6 | 7585.0 |
| RPL28 | 7492.0 |
| RPLP0 | 7456.0 |
| RPS10 | 7422.0 |
| RPS9 | 7239.0 |
| RPL3 | 7066.0 |
| UBA52 | 6901.0 |
| RPL4 | 6839.0 |
| RPL23A | 6780.0 |
| RPS13 | 6745.0 |
| RPL32 | 6717.0 |
| TRAM1 | 6417.0 |
| SRP19 | 6332.0 |
| RPS21 | 6312.0 |
| RPS27A | 6223.0 |
| RPS23 | 6171.0 |
| RPS2 | 6145.0 |
| RPL8 | 6083.0 |
| RPS3A | 5876.0 |
| SEC61A1 | 5685.0 |
| RPS27L | 5650.0 |
| RPS16 | 5552.0 |
| SSR3 | 5516.0 |
| RPL15 | 5410.0 |
| FAU | 5376.0 |
| SRP14 | 5116.0 |
| RPL18 | 4825.0 |
| RPL26 | 4557.0 |
| RPL17 | 4473.0 |
| RPS11 | 4468.0 |
| RPL21 | 4396.0 |
| SPCS2 | 4240.0 |
| RPS20 | 4174.0 |
| RPS15A | 4169.0 |
| RPS8 | 4117.0 |
| RPL30 | 3957.0 |
| SRP72 | 3890.0 |
| RPL26L1 | 3710.0 |
| RPS19 | 3558.0 |
| RPS5 | 3408.0 |
| RPS24 | 3357.0 |
| RPS7 | 3333.0 |
| RPL37A | 3063.0 |
| RPN1 | 2950.0 |
| RPL22 | 2864.0 |
| RPS29 | 2812.0 |
| RPL35 | 2694.0 |
| RPS26 | 2583.0 |
| RPS27 | 2232.0 |
| RPS25 | 2059.0 |
| RPL22L1 | 1785.0 |
| RPS6 | 1237.0 |
| RPL24 | 901.0 |
| RPLP2 | 141.0 |
| SPCS3 | 5.0 |
| SRPRA | -245.0 |
| RPL9 | -399.0 |
| RPL29 | -634.0 |
| RPL36 | -891.0 |
| RPS3 | -935.0 |
| SRP68 | -1319.0 |
| RPN2 | -1352.0 |
| SSR1 | -1706.0 |
| RPL41 | -2639.0 |
| RPL13A | -2765.5 |
| RPS15 | -2768.0 |
| RPL31 | -3475.0 |
| SRPRB | -4503.0 |
| RPL14 | -5770.0 |
| DDOST | -7370.0 |
| SEC61A2 | -8538.0 |
| RPL3L | -10862.0 |
| RPL10L | -10981.0 |
REACTOME_CELLULAR_RESPONSES_TO_STIMULI
| 1314 | |
|---|---|
| set | REACTOME_CELLULAR_RESPONSES_TO_STIMULI |
| setSize | 779 |
| pANOVA | 8.55e-15 |
| s.dist | 0.163 |
| p.adjustANOVA | 2.7e-12 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TUBB8 | 10619 |
| TUBB4B | 10587 |
| CCL2 | 10549 |
| MIR24-2 | 10459 |
| CDKN2B | 10441 |
| ATP6V1G1 | 10435 |
| RPL39L | 10429 |
| RPLP1 | 10383 |
| UBB | 10269 |
| ID1 | 10259 |
| RPL19 | 10237 |
| GSTA3 | 10160 |
| H3C12 | 10132 |
| RPL27A | 10126 |
| RPL38 | 10097 |
| DCP2 | 10068 |
| RPS12 | 10065 |
| HBA1 | 10061 |
| CDK4 | 10023 |
| RPL27 | 10018 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TUBB8 | 10619.0 |
| TUBB4B | 10587.0 |
| CCL2 | 10549.0 |
| MIR24-2 | 10459.0 |
| CDKN2B | 10441.0 |
| ATP6V1G1 | 10435.0 |
| RPL39L | 10429.0 |
| RPLP1 | 10383.0 |
| UBB | 10269.0 |
| ID1 | 10259.0 |
| RPL19 | 10237.0 |
| GSTA3 | 10160.0 |
| H3C12 | 10132.0 |
| RPL27A | 10126.0 |
| RPL38 | 10097.0 |
| DCP2 | 10068.0 |
| RPS12 | 10065.0 |
| HBA1 | 10061.0 |
| CDK4 | 10023.0 |
| RPL27 | 10018.0 |
| COX6A1 | 9998.0 |
| RPS19BP1 | 9995.0 |
| SOD2 | 9985.0 |
| RPL12 | 9972.0 |
| PPP2R5B | 9946.0 |
| HSP90B1 | 9907.0 |
| HSPA13 | 9879.0 |
| RPL5 | 9847.0 |
| RPL10A | 9823.0 |
| NDUFA4 | 9820.0 |
| CYCS | 9761.0 |
| CREB3 | 9651.0 |
| RPA2 | 9599.0 |
| RPSA | 9598.0 |
| GSTA1 | 9541.0 |
| CXCL8 | 9514.0 |
| EEF1A1 | 9508.0 |
| HSBP1 | 9507.0 |
| RPL35A | 9504.0 |
| CALR | 9479.0 |
| HMGA2 | 9477.0 |
| H2BC14 | 9436.0 |
| TINF2 | 9413.0 |
| DNAJB11 | 9409.0 |
| H4C8 | 9408.0 |
| COX16 | 9398.0 |
| TUBA4A | 9371.0 |
| TPR | 9369.0 |
| RPL13 | 9355.0 |
| NUP35 | 9338.0 |
| ETS1 | 9327.0 |
| H2AC14 | 9305.0 |
| KAT5 | 9291.0 |
| PSMB3 | 9282.0 |
| TUBB3 | 9276.0 |
| FKBP14 | 9272.0 |
| RPL11 | 9263.0 |
| ERF | 9251.0 |
| H2BC17 | 9247.0 |
| NUP107 | 9241.0 |
| H3-3A | 9239.0 |
| HSPA2 | 9216.0 |
| H3C3 | 9111.0 |
| PSMA6 | 9088.0 |
| CITED2 | 9037.0 |
| SERP1 | 9033.0 |
| LAMTOR2 | 9029.0 |
| CASTOR1 | 8991.0 |
| RPL34 | 8949.0 |
| PSMA7 | 8947.0 |
| ATP6V1D | 8913.0 |
| H2AZ1 | 8894.0 |
| DNAJC7 | 8864.0 |
| ATP6V1C1 | 8862.0 |
| GCLM | 8854.0 |
| AGO1 | 8794.0 |
| SHC1 | 8788.0 |
| PSME2 | 8738.0 |
| NUP43 | 8731.0 |
| SOD3 | 8706.0 |
| EIF2S2 | 8700.0 |
| LAMTOR4 | 8697.0 |
| PSMC5 | 8695.0 |
| UBC | 8680.0 |
| LMNB1 | 8677.0 |
| PSMA1 | 8676.0 |
| H2BC5 | 8646.0 |
| DDIT3 | 8615.0 |
| EIF2S1 | 8607.0 |
| TUBB2B | 8597.0 |
| SCO1 | 8569.0 |
| CRYAB | 8562.0 |
| AJUBA | 8560.0 |
| MT1G | 8554.0 |
| RPL36AL | 8546.5 |
| MAPK14 | 8531.0 |
| RPL18A | 8433.0 |
| RPS18 | 8418.0 |
| RPL7 | 8407.0 |
| ANAPC16 | 8396.0 |
| SKP2 | 8386.0 |
| HSPB2 | 8381.0 |
| H4C4 | 8378.0 |
| PSMD12 | 8377.0 |
| RPS14 | 8367.0 |
| CEBPB | 8342.0 |
| MEF2D | 8341.0 |
| ATP6V1E2 | 8308.0 |
| CAPZA3 | 8229.0 |
| NUP153 | 8165.0 |
| IDH1 | 8160.0 |
| PSMB1 | 8157.0 |
| EXOSC1 | 8143.0 |
| RPL37 | 8126.0 |
| MYC | 8099.0 |
| HSPA1A | 8066.0 |
| JUN | 8056.0 |
| RPS28 | 8053.0 |
| TUBA4B | 8052.0 |
| PSMC4 | 8042.0 |
| TATDN2 | 8015.0 |
| TUBB6 | 7982.0 |
| H2BC4 | 7968.0 |
| RPL7A | 7958.0 |
| SP1 | 7917.0 |
| COX11 | 7898.0 |
| CREBRF | 7822.0 |
| RPL23 | 7819.0 |
| HSPA8 | 7776.0 |
| TERF2IP | 7705.0 |
| NR1D1 | 7664.0 |
| NUP155 | 7642.0 |
| MT1H | 7638.0 |
| RPL6 | 7585.0 |
| SIN3A | 7575.0 |
| XPO1 | 7555.0 |
| MDM4 | 7548.0 |
| CDKN1B | 7523.0 |
| ASNS | 7511.0 |
| ELOC | 7494.0 |
| RPL28 | 7492.0 |
| DEDD2 | 7468.0 |
| DDX11 | 7457.0 |
| RPLP0 | 7456.0 |
| RPS10 | 7422.0 |
| BLVRB | 7416.0 |
| COX5A | 7405.0 |
| LAMTOR5 | 7399.0 |
| HDGF | 7365.0 |
| ATF2 | 7358.0 |
| EXOSC5 | 7283.0 |
| EXOSC7 | 7271.0 |
| H2AC18 | 7261.5 |
| H2AC19 | 7261.5 |
| ANAPC10 | 7259.0 |
| AKT1S1 | 7256.0 |
| HMOX2 | 7240.0 |
| RPS9 | 7239.0 |
| CREB3L3 | 7227.0 |
| ACTR10 | 7218.0 |
| PSMB9 | 7201.0 |
| WIPI1 | 7139.0 |
| ST13 | 7135.0 |
| TACO1 | 7132.0 |
| COX6B1 | 7125.0 |
| ARNT | 7111.0 |
| GSK3A | 7107.0 |
| RPL3 | 7066.0 |
| DNAJA2 | 7053.0 |
| MTF1 | 7010.0 |
| H2AC6 | 7006.0 |
| CDC26 | 6989.0 |
| EXOSC3 | 6924.0 |
| HSPA5 | 6918.0 |
| UBA52 | 6901.0 |
| CHD9 | 6888.0 |
| TUBA8 | 6874.0 |
| IL1A | 6845.0 |
| RPL4 | 6839.0 |
| MIOS | 6786.0 |
| RPL23A | 6780.0 |
| ANAPC1 | 6773.0 |
| CCS | 6764.0 |
| H2BC15 | 6756.0 |
| H4C3 | 6755.0 |
| RPS13 | 6745.0 |
| ATP6V1G2 | 6743.0 |
| RPL32 | 6717.0 |
| RNF2 | 6706.0 |
| H2BC9 | 6696.5 |
| H3C7 | 6696.5 |
| EDEM1 | 6658.0 |
| BMT2 | 6635.0 |
| ATF4 | 6627.0 |
| TNRC6B | 6600.0 |
| H2AC4 | 6574.0 |
| HIKESHI | 6530.0 |
| TXNIP | 6528.0 |
| HSP90AB1 | 6482.0 |
| H2AZ2 | 6477.0 |
| H4C5 | 6455.0 |
| HSPA1B | 6425.0 |
| KDELR3 | 6415.0 |
| DIS3 | 6405.0 |
| H1-0 | 6389.0 |
| DNAJB9 | 6368.0 |
| ATP6V0D2 | 6329.0 |
| RPS21 | 6312.0 |
| EGLN1 | 6311.0 |
| PSMB7 | 6283.0 |
| GPX7 | 6260.0 |
| DYNC1I2 | 6238.0 |
| PGR | 6231.0 |
| RPS27A | 6223.0 |
| PSMB10 | 6211.0 |
| CAPZA1 | 6183.0 |
| EXOSC4 | 6174.0 |
| RPS23 | 6171.0 |
| RPS2 | 6145.0 |
| CDK2 | 6121.0 |
| COX7A2L | 6108.0 |
| RPL8 | 6083.0 |
| MRPL18 | 6071.0 |
| NOX4 | 6056.0 |
| H1-3 | 6042.0 |
| FOS | 6017.0 |
| PSMB8 | 6003.0 |
| NUDT2 | 5980.0 |
| CDKN2D | 5979.0 |
| EXOSC8 | 5963.0 |
| DCTN5 | 5922.0 |
| PSMD13 | 5916.0 |
| RBBP4 | 5906.0 |
| PRDX3 | 5900.0 |
| RPS3A | 5876.0 |
| HERPUD1 | 5844.0 |
| ATP6V0E1 | 5840.0 |
| MT1A | 5813.0 |
| BAG5 | 5769.0 |
| CDKN2A | 5761.0 |
| TGS1 | 5759.0 |
| ATP6V0E2 | 5729.0 |
| DNAJC2 | 5694.0 |
| MT1X | 5691.0 |
| SCO2 | 5680.0 |
| NUP54 | 5663.0 |
| RPS27L | 5650.0 |
| CSNK2B | 5641.0 |
| EED | 5630.0 |
| SNCB | 5607.0 |
| KICS2 | 5603.0 |
| RPS16 | 5552.0 |
| NUP50 | 5527.0 |
| TNFRSF21 | 5471.0 |
| MT1E | 5465.0 |
| H1-2 | 5449.0 |
| NR3C1 | 5426.0 |
| PSMC6 | 5420.0 |
| RPL15 | 5410.0 |
| SKP1 | 5377.0 |
| FAU | 5376.0 |
| HDAC3 | 5330.0 |
| CHAC1 | 5264.0 |
| BRCA1 | 5239.0 |
| UBXN7 | 5193.0 |
| COX6C | 5172.0 |
| UBE2D3 | 5120.0 |
| RPA3 | 5112.0 |
| PHC3 | 5054.0 |
| H2BC3 | 5022.0 |
| SLC7A11 | 4995.0 |
| PSMA4 | 4963.0 |
| PSMD7 | 4932.0 |
| DNAJA1 | 4915.0 |
| COX4I1 | 4877.0 |
| MEF2C | 4874.0 |
| HSPA14 | 4855.0 |
| H4C9 | 4853.0 |
| RPL18 | 4825.0 |
| NFE2L2 | 4811.0 |
| P4HB | 4781.0 |
| H4C16 | 4688.0 |
| HSPH1 | 4667.0 |
| H2AJ | 4666.0 |
| CEBPG | 4662.0 |
| HMGA1 | 4651.0 |
| NRIP1 | 4619.0 |
| EGLN2 | 4607.0 |
| E2F3 | 4591.0 |
| MRE11 | 4573.0 |
| GPX1 | 4563.0 |
| RPL26 | 4557.0 |
| H2BC6 | 4552.0 |
| BMI1 | 4535.0 |
| ATP6V0C | 4517.0 |
| TPP1 | 4497.0 |
| RPL17 | 4473.0 |
| RPS11 | 4468.0 |
| RPL21 | 4396.0 |
| POM121 | 4393.0 |
| ELOB | 4304.0 |
| H4C2 | 4300.0 |
| EIF2AK3 | 4291.0 |
| STAT3 | 4231.0 |
| PPP1R15A | 4201.0 |
| XBP1 | 4196.0 |
| RPS20 | 4174.0 |
| RPS15A | 4169.0 |
| RPS8 | 4117.0 |
| PSMA3 | 4116.0 |
| HIF1A | 4112.0 |
| H4C6 | 4018.0 |
| GSK3B | 4006.0 |
| RPL30 | 3957.0 |
| NPRL2 | 3952.0 |
| IL6 | 3948.0 |
| SUZ12 | 3929.0 |
| MAFG | 3926.0 |
| KDM6B | 3888.0 |
| RBX1 | 3880.0 |
| IGFBP1 | 3785.0 |
| POM121C | 3776.0 |
| RPL26L1 | 3710.0 |
| KHSRP | 3662.0 |
| H2BC12 | 3661.0 |
| DCTN6 | 3650.0 |
| EPO | 3620.0 |
| CYBA | 3616.0 |
| CREB3L1 | 3592.0 |
| RPS19 | 3558.0 |
| DYNC1LI1 | 3543.0 |
| ATM | 3539.0 |
| GPX3 | 3454.0 |
| CCNA1 | 3453.0 |
| HSPB1 | 3432.0 |
| NUP133 | 3422.0 |
| RPS5 | 3408.0 |
| NFYB | 3373.0 |
| RPS24 | 3357.0 |
| GSTP1 | 3356.0 |
| RPS7 | 3333.0 |
| TERF2 | 3331.0 |
| PSMB2 | 3326.0 |
| TLR4 | 3293.0 |
| H2AC20 | 3275.0 |
| ATR | 3230.0 |
| TUBA1B | 3208.0 |
| NUP205 | 3185.0 |
| HSPA12B | 3170.0 |
| LIMD1 | 3094.0 |
| SESN1 | 3069.0 |
| RPL37A | 3063.0 |
| PSMB4 | 3049.0 |
| TBL1XR1 | 3008.0 |
| PSMC1 | 2987.0 |
| H3C2 | 2976.0 |
| CLEC1B | 2973.0 |
| MAP2K3 | 2877.0 |
| RPL22 | 2864.0 |
| MAPK10 | 2842.0 |
| HIGD1A | 2829.0 |
| PALB2 | 2817.0 |
| RPS29 | 2812.0 |
| NCOA6 | 2762.0 |
| CAT | 2753.0 |
| ANAPC15 | 2703.0 |
| RPL35 | 2694.0 |
| HSPA9 | 2683.0 |
| COX18 | 2659.0 |
| ACADVL | 2639.0 |
| CAPZB | 2596.0 |
| POT1 | 2588.0 |
| RPS26 | 2583.0 |
| ATP6V1B2 | 2582.0 |
| CUL1 | 2567.0 |
| UBE2S | 2530.0 |
| TXN | 2519.0 |
| H2BC11 | 2506.0 |
| SLC46A1 | 2468.0 |
| CDK6 | 2462.0 |
| NCOA1 | 2431.0 |
| YWHAE | 2415.0 |
| NDC1 | 2410.0 |
| IGFBP7 | 2407.0 |
| FNIP2 | 2386.0 |
| PSMA8 | 2379.0 |
| ATF3 | 2309.0 |
| CDC27 | 2297.0 |
| DCTN2 | 2252.0 |
| RPS27 | 2232.0 |
| BAG3 | 2187.0 |
| PSMD1 | 2144.0 |
| MAPK1 | 2130.0 |
| MAPK7 | 2129.0 |
| PSME4 | 2128.0 |
| COX20 | 2082.0 |
| PSMB5 | 2078.0 |
| GOSR2 | 2060.0 |
| RPS25 | 2059.0 |
| HSP90AA1 | 2049.0 |
| RRAGC | 1990.0 |
| CDC23 | 1913.0 |
| NQO1 | 1911.0 |
| DYNC1I1 | 1903.0 |
| ME1 | 1888.0 |
| RRAGA | 1886.0 |
| RPL22L1 | 1785.0 |
| UBE2D2 | 1776.0 |
| PSMC3 | 1749.0 |
| RRAGD | 1739.0 |
| H2BC21 | 1717.0 |
| IMPACT | 1688.0 |
| SEM1 | 1657.0 |
| PSMC2 | 1653.0 |
| ACTR1A | 1641.0 |
| CREB1 | 1614.0 |
| CBX4 | 1588.0 |
| FNIP1 | 1570.0 |
| BAG4 | 1550.0 |
| MAP4K4 | 1547.0 |
| BLVRA | 1530.0 |
| ANAPC5 | 1528.0 |
| E2F1 | 1406.0 |
| PSMD4 | 1403.0 |
| ANAPC7 | 1287.0 |
| MT2A | 1285.0 |
| NUP88 | 1277.0 |
| EXTL2 | 1240.0 |
| RPS6 | 1237.0 |
| PHC1 | 1236.0 |
| RAE1 | 1215.0 |
| MT1F | 1201.0 |
| RANBP2 | 1191.0 |
| LAMTOR3 | 1190.0 |
| H1-1 | 985.0 |
| UBE2E1 | 974.0 |
| HIF3A | 970.0 |
| RORA | 967.0 |
| TERF1 | 948.0 |
| RPL24 | 901.0 |
| TP53 | 830.0 |
| RAD50 | 807.0 |
| PRKCD | 775.0 |
| H2AX | 764.0 |
| ATP6V1A | 718.0 |
| MAPKAPK5 | 691.0 |
| PSMA5 | 665.0 |
| NFYA | 629.0 |
| NUP160 | 618.0 |
| H3C11 | 608.0 |
| ATP6V1E1 | 596.0 |
| NCOR1 | 549.0 |
| TNIK | 548.0 |
| MDM2 | 542.0 |
| COX5B | 536.0 |
| CCNA2 | 521.0 |
| SYVN1 | 511.0 |
| PSMA2 | 467.0 |
| CDKN2C | 433.0 |
| EZH2 | 400.0 |
| COX8A | 395.0 |
| CCNE2 | 369.0 |
| NUP98 | 368.0 |
| STAP2 | 359.0 |
| TXNRD1 | 306.0 |
| ATF6 | 294.0 |
| PSMD3 | 274.0 |
| COX19 | 256.0 |
| FKBP4 | 255.0 |
| CREB3L2 | 253.0 |
| HSPA4L | 240.0 |
| PGD | 226.0 |
| CREB3L4 | 220.0 |
| HSPA6 | 146.0 |
| RPLP2 | 141.0 |
| NR3C2 | 97.0 |
| AGO3 | 75.0 |
| MT3 | 72.0 |
| UBN1 | 25.0 |
| NFKB1 | 12.0 |
| CRTC3 | 0.0 |
| H4C1 | -64.0 |
| RPA1 | -66.0 |
| UFD1 | -127.0 |
| ANAPC11 | -133.0 |
| RB1 | -156.0 |
| H3C6 | -174.0 |
| PSMD14 | -192.0 |
| ATP6V1F | -216.0 |
| BTRC | -218.0 |
| SRPRA | -245.0 |
| ADD1 | -289.0 |
| ERO1A | -392.0 |
| RPL9 | -399.0 |
| ATP6V0B | -401.0 |
| DCSTAMP | -402.0 |
| CSNK2A1 | -415.0 |
| NFYC | -421.0 |
| PTGES3 | -434.0 |
| PRDX5 | -512.0 |
| TUBB4A | -521.0 |
| DCTN4 | -574.0 |
| PSME3 | -576.0 |
| RHEB | -599.0 |
| HSPA1L | -608.0 |
| H2BC10 | -630.0 |
| RPL29 | -634.0 |
| SEH1L | -682.0 |
| UBE2C | -737.0 |
| SQSTM1 | -813.0 |
| PSME1 | -840.0 |
| RPL36 | -891.0 |
| KLHDC3 | -909.0 |
| ITFG2 | -918.0 |
| RPS3 | -935.0 |
| TFDP2 | -949.0 |
| PARN | -1017.0 |
| PDIA6 | -1054.0 |
| H3C8 | -1062.0 |
| COX14 | -1067.0 |
| PSMD6 | -1076.0 |
| PSMD11 | -1095.0 |
| EP300 | -1121.0 |
| NUP42 | -1128.0 |
| H4C13 | -1134.0 |
| TUBA1A | -1153.0 |
| SESN2 | -1204.0 |
| CCNE1 | -1241.0 |
| LY96 | -1328.0 |
| GCLC | -1348.0 |
| DYNLL1 | -1359.0 |
| GPX8 | -1399.0 |
| ASF1A | -1412.0 |
| CRTC2 | -1460.0 |
| MAPKAPK3 | -1461.0 |
| PSMD5 | -1600.0 |
| VHL | -1609.0 |
| H3-3B | -1628.0 |
| MAP1LC3B | -1634.0 |
| KPTN | -1638.0 |
| SSR1 | -1706.0 |
| PSMD8 | -1715.0 |
| MAPK8 | -1743.0 |
| EIF2AK1 | -1754.0 |
| ANAPC4 | -1773.0 |
| NUP37 | -1790.0 |
| PRDX2 | -1840.0 |
| PSMD9 | -1897.0 |
| H4C12 | -1933.0 |
| EGLN3 | -1994.0 |
| MAPKAPK2 | -1995.0 |
| H3C1 | -2029.0 |
| MUL1 | -2044.0 |
| APOA1 | -2062.0 |
| TKT | -2084.0 |
| VEGFA | -2133.0 |
| TNRC6A | -2135.0 |
| MT1M | -2315.0 |
| CAMK2D | -2329.0 |
| SEC13 | -2354.0 |
| ATP6V1H | -2355.0 |
| STIP1 | -2374.0 |
| PPARGC1A | -2397.0 |
| DCTN3 | -2491.0 |
| APOB | -2506.0 |
| H1-5 | -2519.0 |
| CDC16 | -2545.0 |
| USP46 | -2560.0 |
| RPL41 | -2639.0 |
| GRB10 | -2648.0 |
| SURF1 | -2649.0 |
| TALDO1 | -2686.0 |
| TUBB2A | -2758.0 |
| RPL13A | -2765.5 |
| RPS15 | -2768.0 |
| ATP6V1G3 | -2787.0 |
| LAMTOR1 | -2877.0 |
| NCF2 | -2936.0 |
| MAFK | -3017.0 |
| EXOSC9 | -3019.0 |
| WDR59 | -3177.0 |
| DNAJB1 | -3250.0 |
| LMNA | -3342.0 |
| MYDGF | -3351.0 |
| FKBP5 | -3355.0 |
| SCMH1 | -3398.0 |
| NLRP3 | -3412.0 |
| MAP3K5 | -3415.0 |
| H2BC13 | -3416.0 |
| TXN2 | -3426.0 |
| RPS6KA1 | -3467.0 |
| RPL31 | -3475.0 |
| CDKN1A | -3505.0 |
| PRDX1 | -3592.0 |
| SMARCD3 | -3674.0 |
| MOV10 | -3677.0 |
| H1-4 | -3705.0 |
| ATP6V1B1 | -3735.0 |
| GPX5 | -3760.0 |
| RLN1 | -3794.0 |
| LRPPRC | -3867.0 |
| TLN1 | -3912.0 |
| GSR | -4001.0 |
| EXOSC2 | -4135.0 |
| CAMK2B | -4174.0 |
| PSMF1 | -4178.0 |
| ALB | -4179.0 |
| HSPA12A | -4183.0 |
| H3C4 | -4187.0 |
| CAPZA2 | -4200.0 |
| CSNK2A2 | -4208.0 |
| H2AC7 | -4211.0 |
| H2BC7 | -4211.0 |
| MAPK11 | -4242.0 |
| NOX5 | -4258.0 |
| H2AC8 | -4264.0 |
| TXNRD2 | -4271.0 |
| SIRT1 | -4337.0 |
| CSRP1 | -4343.0 |
| ATF5 | -4460.0 |
| NUP214 | -4467.0 |
| NCOA2 | -4468.0 |
| SRPRB | -4503.0 |
| PRDX6 | -4507.0 |
| SLC38A9 | -4527.0 |
| HBA2 | -4536.0 |
| HIF1AN | -4623.0 |
| H3-4 | -4629.0 |
| HM13 | -4655.0 |
| CLOCK | -4673.0 |
| IFNB1 | -4761.0 |
| NBN | -4811.0 |
| TUBA1C | -4828.0 |
| CA9 | -4829.0 |
| ACD | -4835.5 |
| MT1B | -4890.0 |
| GML | -4913.0 |
| SEC31A | -4962.0 |
| VCP | -5021.0 |
| H2BC8 | -5026.0 |
| BACH1 | -5039.0 |
| AKT3 | -5060.0 |
| BAG2 | -5067.0 |
| FABP1 | -5068.0 |
| MAP2K7 | -5085.0 |
| TNRC6C | -5100.0 |
| ATOX1 | -5113.0 |
| ETS2 | -5123.0 |
| PREB | -5141.0 |
| NUP93 | -5201.0 |
| DCTN1 | -5208.0 |
| PHC2 | -5228.0 |
| CAMK2G | -5275.0 |
| PSMB6 | -5356.0 |
| FBXL17 | -5385.0 |
| E2F2 | -5404.0 |
| DYNC1LI2 | -5447.0 |
| AGO4 | -5477.0 |
| MAP2K6 | -5479.0 |
| CBX2 | -5495.0 |
| CTDSP2 | -5500.0 |
| HSPB8 | -5602.0 |
| UBE2D1 | -5677.0 |
| RPL14 | -5770.0 |
| EPAS1 | -5842.0 |
| CUL2 | -5892.0 |
| EIF2AK4 | -5914.0 |
| RELA | -6000.0 |
| SIN3B | -6003.0 |
| RING1 | -6082.0 |
| NUP62 | -6129.0 |
| CAMK2A | -6130.0 |
| PSMD2 | -6144.0 |
| EXOSC6 | -6161.0 |
| MBTPS1 | -6190.0 |
| VENTX | -6197.0 |
| CUL3 | -6363.0 |
| ABCC1 | -6370.0 |
| GPX6 | -6394.0 |
| CBX6 | -6420.0 |
| HELZ2 | -6455.0 |
| MED1 | -6464.0 |
| RPTOR | -6584.0 |
| SERPINH1 | -6603.0 |
| BMAL1 | -6641.0 |
| DYNLL2 | -6691.0 |
| YIF1A | -6828.0 |
| NCF4 | -7083.0 |
| NUP188 | -7120.0 |
| KEAP1 | -7145.0 |
| HSPA4 | -7149.0 |
| NPLOC4 | -7155.0 |
| COX7C | -7158.0 |
| DEPDC5 | -7248.0 |
| EP400 | -7289.0 |
| MAP2K4 | -7373.0 |
| HIRA | -7389.0 |
| H2BC26 | -7437.0 |
| SRXN1 | -7445.0 |
| TUBAL3 | -7519.0 |
| WTIP | -7535.0 |
| RAI1 | -7548.0 |
| RPS6KA2 | -7552.0 |
| CXXC1 | -7593.0 |
| EHMT2 | -7650.0 |
| EXTL1 | -7743.0 |
| PPARA | -7755.0 |
| MAPK9 | -7770.0 |
| FZR1 | -7779.0 |
| NUP58 | -7794.0 |
| EXTL3 | -7825.0 |
| EHMT1 | -7943.0 |
| GFPT1 | -7945.0 |
| TUBA3C | -7998.0 |
| ERN1 | -8043.0 |
| H2BC1 | -8099.0 |
| WFS1 | -8101.0 |
| TUBB1 | -8166.0 |
| NUP85 | -8221.0 |
| AAAS | -8286.0 |
| ATP6V1C2 | -8320.0 |
| NPAS2 | -8335.0 |
| MLST8 | -8336.0 |
| CREBBP | -8338.0 |
| CCAR2 | -8390.0 |
| BAG1 | -8412.0 |
| ARFGAP1 | -8500.0 |
| NUP210 | -8505.0 |
| H3C10 | -8558.0 |
| TRIB3 | -8559.0 |
| SOD1 | -8579.0 |
| DNAJB6 | -8614.0 |
| TUBA3E | -8617.0 |
| SH3BP4 | -8720.0 |
| MTOR | -8832.0 |
| TFDP1 | -8835.0 |
| TCIRG1 | -8869.0 |
| HMOX1 | -8934.0 |
| ZBTB17 | -8952.0 |
| NCOR2 | -9014.0 |
| RXRA | -9025.0 |
| PDIA5 | -9030.0 |
| DNAJA4 | -9102.0 |
| H4C11 | -9168.0 |
| CRYBA4 | -9180.0 |
| ATP6V0D1 | -9295.0 |
| FLCN | -9328.0 |
| CABIN1 | -9344.0 |
| SZT2 | -9361.0 |
| TRIM21 | -9443.0 |
| HBB | -9476.0 |
| DNAJC3 | -9484.0 |
| DYNC1H1 | -9522.0 |
| ANAPC2 | -9561.0 |
| AKT2 | -9562.0 |
| GPX2 | -9576.0 |
| MT4 | -9599.0 |
| CRTC1 | -9614.0 |
| HYOU1 | -9662.0 |
| NOTCH1 | -9691.0 |
| MIR24-1 | -9733.0 |
| MAPK3 | -9797.0 |
| CBX8 | -9809.0 |
| HSF1 | -9901.0 |
| DPP3 | -9950.0 |
| WDR24 | -9977.0 |
| AKT1 | -10034.0 |
| MINK1 | -10185.0 |
| GCN1 | -10186.0 |
| CUL7 | -10210.0 |
| NPRL3 | -10269.0 |
| CARM1 | -10282.0 |
| AQP8 | -10323.0 |
| PTK6 | -10535.0 |
| PSMB11 | -10657.0 |
| TUBA3D | -10666.0 |
| RPL3L | -10862.0 |
| RPL10L | -10981.0 |
| PLA2G4B | -11015.0 |
REACTOME_EUKARYOTIC_TRANSLATION_INITIATION
| 1149 | |
|---|---|
| set | REACTOME_EUKARYOTIC_TRANSLATION_INITIATION |
| setSize | 110 |
| pANOVA | 9.86e-15 |
| s.dist | 0.427 |
| p.adjustANOVA | 2.7e-12 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL39L | 10429 |
| RPLP1 | 10383 |
| EIF2B1 | 10258 |
| RPL19 | 10237 |
| RPL27A | 10126 |
| RPL38 | 10097 |
| RPS12 | 10065 |
| RPL27 | 10018 |
| EIF3J | 9988 |
| RPL12 | 9972 |
| EIF2B4 | 9865 |
| RPL5 | 9847 |
| RPL10A | 9823 |
| EIF4A1 | 9700 |
| RPSA | 9598 |
| RPL35A | 9504 |
| RPL13 | 9355 |
| RPL11 | 9263 |
| RPL34 | 8949 |
| EIF5B | 8800 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL39L | 10429.0 |
| RPLP1 | 10383.0 |
| EIF2B1 | 10258.0 |
| RPL19 | 10237.0 |
| RPL27A | 10126.0 |
| RPL38 | 10097.0 |
| RPS12 | 10065.0 |
| RPL27 | 10018.0 |
| EIF3J | 9988.0 |
| RPL12 | 9972.0 |
| EIF2B4 | 9865.0 |
| RPL5 | 9847.0 |
| RPL10A | 9823.0 |
| EIF4A1 | 9700.0 |
| RPSA | 9598.0 |
| RPL35A | 9504.0 |
| RPL13 | 9355.0 |
| RPL11 | 9263.0 |
| RPL34 | 8949.0 |
| EIF5B | 8800.0 |
| EIF4H | 8713.0 |
| EIF2S2 | 8700.0 |
| EIF2S1 | 8607.0 |
| RPL36AL | 8546.5 |
| RPL18A | 8433.0 |
| RPS18 | 8418.0 |
| RPL7 | 8407.0 |
| RPS14 | 8367.0 |
| RPL37 | 8126.0 |
| RPS28 | 8053.0 |
| RPL7A | 7958.0 |
| RPL23 | 7819.0 |
| RPL6 | 7585.0 |
| RPL28 | 7492.0 |
| RPLP0 | 7456.0 |
| RPS10 | 7422.0 |
| EIF2B2 | 7382.0 |
| RPS9 | 7239.0 |
| RPL3 | 7066.0 |
| EIF2B5 | 7028.0 |
| UBA52 | 6901.0 |
| RPL4 | 6839.0 |
| RPL23A | 6780.0 |
| RPS13 | 6745.0 |
| RPL32 | 6717.0 |
| EIF3G | 6501.0 |
| RPS21 | 6312.0 |
| EIF3F | 6280.0 |
| RPS27A | 6223.0 |
| RPS23 | 6171.0 |
| RPS2 | 6145.0 |
| RPL8 | 6083.0 |
| RPS3A | 5876.0 |
| EIF3K | 5774.0 |
| RPS27L | 5650.0 |
| RPS16 | 5552.0 |
| RPL15 | 5410.0 |
| FAU | 5376.0 |
| EIF3I | 5206.0 |
| EIF4E | 4924.0 |
| RPL18 | 4825.0 |
| RPL26 | 4557.0 |
| RPL17 | 4473.0 |
| RPS11 | 4468.0 |
| RPL21 | 4396.0 |
| RPS20 | 4174.0 |
| RPS15A | 4169.0 |
| RPS8 | 4117.0 |
| RPL30 | 3957.0 |
| RPL26L1 | 3710.0 |
| EIF3L | 3580.0 |
| RPS19 | 3558.0 |
| RPS5 | 3408.0 |
| RPS24 | 3357.0 |
| RPS7 | 3333.0 |
| EIF4A2 | 3182.0 |
| RPL37A | 3063.0 |
| RPL22 | 2864.0 |
| RPS29 | 2812.0 |
| RPL35 | 2694.0 |
| RPS26 | 2583.0 |
| RPS27 | 2232.0 |
| RPS25 | 2059.0 |
| RPL22L1 | 1785.0 |
| EIF5 | 1315.0 |
| RPS6 | 1237.0 |
| RPL24 | 901.0 |
| EIF3M | 574.0 |
| PABPC1 | 181.0 |
| EIF4G1 | 169.0 |
| RPLP2 | 141.0 |
| EIF3E | -214.0 |
| RPL9 | -399.0 |
| RPL29 | -634.0 |
| RPL36 | -891.0 |
| RPS3 | -935.0 |
| EIF4B | -1756.0 |
| RPL41 | -2639.0 |
| RPL13A | -2765.5 |
| RPS15 | -2768.0 |
| RPL31 | -3475.0 |
| EIF2B3 | -3754.0 |
| EIF3D | -4500.0 |
| RPL14 | -5770.0 |
| EIF3B | -6053.0 |
| EIF4EBP1 | -6620.0 |
| EIF3A | -7122.0 |
| EIF3H | -7385.0 |
| RPL3L | -10862.0 |
| RPL10L | -10981.0 |
REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS
| 1364 | |
|---|---|
| set | REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS |
| setSize | 161 |
| pANOVA | 1.22e-14 |
| s.dist | 0.352 |
| p.adjustANOVA | 2.87e-12 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL39L | 10429 |
| RPLP1 | 10383 |
| UBB | 10269 |
| RPL19 | 10237 |
| RPL27A | 10126 |
| RPL38 | 10097 |
| RPS12 | 10065 |
| RPL27 | 10018 |
| RPL12 | 9972 |
| RPL5 | 9847 |
| RPL10A | 9823 |
| RPSA | 9598 |
| RPL35A | 9504 |
| RPL13 | 9355 |
| PSMB3 | 9282 |
| RPL11 | 9263 |
| RBM8A | 9093 |
| PSMA6 | 9088 |
| RPL34 | 8949 |
| PSMA7 | 8947 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL39L | 10429.0 |
| RPLP1 | 10383.0 |
| UBB | 10269.0 |
| RPL19 | 10237.0 |
| RPL27A | 10126.0 |
| RPL38 | 10097.0 |
| RPS12 | 10065.0 |
| RPL27 | 10018.0 |
| RPL12 | 9972.0 |
| RPL5 | 9847.0 |
| RPL10A | 9823.0 |
| RPSA | 9598.0 |
| RPL35A | 9504.0 |
| RPL13 | 9355.0 |
| PSMB3 | 9282.0 |
| RPL11 | 9263.0 |
| RBM8A | 9093.0 |
| PSMA6 | 9088.0 |
| RPL34 | 8949.0 |
| PSMA7 | 8947.0 |
| ETF1 | 8741.0 |
| PSME2 | 8738.0 |
| PSMC5 | 8695.0 |
| UBC | 8680.0 |
| PSMA1 | 8676.0 |
| RPL36AL | 8546.5 |
| ISL1 | 8475.0 |
| RPL18A | 8433.0 |
| RPS18 | 8418.0 |
| RPL7 | 8407.0 |
| PSMD12 | 8377.0 |
| RPS14 | 8367.0 |
| PSMB1 | 8157.0 |
| RPL37 | 8126.0 |
| UPF2 | 8123.0 |
| RPS28 | 8053.0 |
| PSMC4 | 8042.0 |
| LDB1 | 8039.0 |
| RPL7A | 7958.0 |
| RPL23 | 7819.0 |
| LHX9 | 7783.0 |
| RPL6 | 7585.0 |
| ELOC | 7494.0 |
| RPL28 | 7492.0 |
| RPLP0 | 7456.0 |
| RPS10 | 7422.0 |
| RPS9 | 7239.0 |
| PSMB9 | 7201.0 |
| RPL3 | 7066.0 |
| UBA52 | 6901.0 |
| RPL4 | 6839.0 |
| RPL23A | 6780.0 |
| RPS13 | 6745.0 |
| RPL32 | 6717.0 |
| ROBO3 | 6480.0 |
| RPS21 | 6312.0 |
| PSMB7 | 6283.0 |
| RPS27A | 6223.0 |
| PSMB10 | 6211.0 |
| RPS23 | 6171.0 |
| RPS2 | 6145.0 |
| RPL8 | 6083.0 |
| PSMB8 | 6003.0 |
| PSMD13 | 5916.0 |
| RPS3A | 5876.0 |
| RPS27L | 5650.0 |
| RPS16 | 5552.0 |
| PSMC6 | 5420.0 |
| RPL15 | 5410.0 |
| FAU | 5376.0 |
| LHX4 | 5348.0 |
| PSMA4 | 4963.0 |
| PSMD7 | 4932.0 |
| RPL18 | 4825.0 |
| LHX2 | 4657.0 |
| NCBP1 | 4593.0 |
| RPL26 | 4557.0 |
| RPL17 | 4473.0 |
| RPS11 | 4468.0 |
| RPL21 | 4396.0 |
| ELOB | 4304.0 |
| RPS20 | 4174.0 |
| RPS15A | 4169.0 |
| RPS8 | 4117.0 |
| PSMA3 | 4116.0 |
| RPL30 | 3957.0 |
| RBX1 | 3880.0 |
| RPL26L1 | 3710.0 |
| RPS19 | 3558.0 |
| RPS5 | 3408.0 |
| RPS24 | 3357.0 |
| RPS7 | 3333.0 |
| PSMB2 | 3326.0 |
| RPL37A | 3063.0 |
| PSMB4 | 3049.0 |
| PSMC1 | 2987.0 |
| RPL22 | 2864.0 |
| RPS29 | 2812.0 |
| RPL35 | 2694.0 |
| RPS26 | 2583.0 |
| SLIT2 | 2470.0 |
| PSMA8 | 2379.0 |
| RPS27 | 2232.0 |
| PSMD1 | 2144.0 |
| PSME4 | 2128.0 |
| USP33 | 2079.0 |
| PSMB5 | 2078.0 |
| RPS25 | 2059.0 |
| UPF3A | 1945.0 |
| RPL22L1 | 1785.0 |
| MAGOH | 1757.0 |
| PSMC3 | 1749.0 |
| GSPT1 | 1694.0 |
| SEM1 | 1657.0 |
| PSMC2 | 1653.0 |
| NCBP2 | 1556.0 |
| CASC3 | 1522.0 |
| PSMD4 | 1403.0 |
| ROBO1 | 1340.0 |
| RPS6 | 1237.0 |
| RNPS1 | 1122.0 |
| RPL24 | 901.0 |
| PSMA5 | 665.0 |
| PSMA2 | 467.0 |
| PSMD3 | 274.0 |
| PABPC1 | 181.0 |
| EIF4G1 | 169.0 |
| RPLP2 | 141.0 |
| PSMD14 | -192.0 |
| RPL9 | -399.0 |
| PSME3 | -576.0 |
| RPL29 | -634.0 |
| MAGOHB | -712.0 |
| PSME1 | -840.0 |
| RPL36 | -891.0 |
| RPS3 | -935.0 |
| PSMD6 | -1076.0 |
| PSMD11 | -1095.0 |
| PSMD5 | -1600.0 |
| PSMD8 | -1715.0 |
| PSMD9 | -1897.0 |
| RPL41 | -2639.0 |
| RPL13A | -2765.5 |
| RPS15 | -2768.0 |
| LHX3 | -3024.0 |
| RPL31 | -3475.0 |
| PSMF1 | -4178.0 |
| PSMB6 | -5356.0 |
| SLIT1 | -5446.0 |
| RPL14 | -5770.0 |
| CUL2 | -5892.0 |
| ROBO2 | -5921.0 |
| PSMD2 | -6144.0 |
| MSI1 | -6307.0 |
| DAG1 | -7442.0 |
| HOXA2 | -7605.0 |
| EIF4A3 | -8763.0 |
| ZSWIM8 | -9658.0 |
| PSMB11 | -10657.0 |
| RPL3L | -10862.0 |
| RPL10L | -10981.0 |
REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY
| 1486 | |
|---|---|
| set | REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY |
| setSize | 94 |
| pANOVA | 6.66e-14 |
| s.dist | 0.447 |
| p.adjustANOVA | 1.37e-11 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL39L | 10429.0 |
| RPLP1 | 10383.0 |
| RPL19 | 10237.0 |
| RPL27A | 10126.0 |
| RPL38 | 10097.0 |
| RPS12 | 10065.0 |
| RPL27 | 10018.0 |
| RPL12 | 9972.0 |
| RPL5 | 9847.0 |
| RPL10A | 9823.0 |
| RPSA | 9598.0 |
| RPL35A | 9504.0 |
| RPL13 | 9355.0 |
| RPL11 | 9263.0 |
| RPL34 | 8949.0 |
| EIF2S2 | 8700.0 |
| DDIT3 | 8615.0 |
| EIF2S1 | 8607.0 |
| RPL36AL | 8546.5 |
| RPL18A | 8433.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL39L | 10429.0 |
| RPLP1 | 10383.0 |
| RPL19 | 10237.0 |
| RPL27A | 10126.0 |
| RPL38 | 10097.0 |
| RPS12 | 10065.0 |
| RPL27 | 10018.0 |
| RPL12 | 9972.0 |
| RPL5 | 9847.0 |
| RPL10A | 9823.0 |
| RPSA | 9598.0 |
| RPL35A | 9504.0 |
| RPL13 | 9355.0 |
| RPL11 | 9263.0 |
| RPL34 | 8949.0 |
| EIF2S2 | 8700.0 |
| DDIT3 | 8615.0 |
| EIF2S1 | 8607.0 |
| RPL36AL | 8546.5 |
| RPL18A | 8433.0 |
| RPS18 | 8418.0 |
| RPL7 | 8407.0 |
| RPS14 | 8367.0 |
| CEBPB | 8342.0 |
| RPL37 | 8126.0 |
| RPS28 | 8053.0 |
| RPL7A | 7958.0 |
| RPL23 | 7819.0 |
| RPL6 | 7585.0 |
| ASNS | 7511.0 |
| RPL28 | 7492.0 |
| RPLP0 | 7456.0 |
| RPS10 | 7422.0 |
| ATF2 | 7358.0 |
| RPS9 | 7239.0 |
| RPL3 | 7066.0 |
| UBA52 | 6901.0 |
| RPL4 | 6839.0 |
| RPL23A | 6780.0 |
| RPS13 | 6745.0 |
| RPL32 | 6717.0 |
| ATF4 | 6627.0 |
| RPS21 | 6312.0 |
| RPS27A | 6223.0 |
| RPS23 | 6171.0 |
| RPS2 | 6145.0 |
| RPL8 | 6083.0 |
| RPS3A | 5876.0 |
| RPS27L | 5650.0 |
| RPS16 | 5552.0 |
| RPL15 | 5410.0 |
| FAU | 5376.0 |
| RPL18 | 4825.0 |
| CEBPG | 4662.0 |
| RPL26 | 4557.0 |
| RPL17 | 4473.0 |
| RPS11 | 4468.0 |
| RPL21 | 4396.0 |
| RPS20 | 4174.0 |
| RPS15A | 4169.0 |
| RPS8 | 4117.0 |
| RPL30 | 3957.0 |
| RPL26L1 | 3710.0 |
| RPS19 | 3558.0 |
| RPS5 | 3408.0 |
| RPS24 | 3357.0 |
| RPS7 | 3333.0 |
| RPL37A | 3063.0 |
| RPL22 | 2864.0 |
| RPS29 | 2812.0 |
| RPL35 | 2694.0 |
| RPS26 | 2583.0 |
| ATF3 | 2309.0 |
| RPS27 | 2232.0 |
| RPS25 | 2059.0 |
| RPL22L1 | 1785.0 |
| IMPACT | 1688.0 |
| RPS6 | 1237.0 |
| RPL24 | 901.0 |
| RPLP2 | 141.0 |
| RPL9 | -399.0 |
| RPL29 | -634.0 |
| RPL36 | -891.0 |
| RPS3 | -935.0 |
| RPL41 | -2639.0 |
| RPL13A | -2765.5 |
| RPS15 | -2768.0 |
| RPL31 | -3475.0 |
| RPL14 | -5770.0 |
| EIF2AK4 | -5914.0 |
| TRIB3 | -8559.0 |
| GCN1 | -10186.0 |
| RPL3L | -10862.0 |
| RPL10L | -10981.0 |
REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION
| 151 | |
|---|---|
| set | REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION |
| setSize | 87 |
| pANOVA | 1.92e-13 |
| s.dist | 0.456 |
| p.adjustANOVA | 3.5e-11 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL39L | 10429.0 |
| RPLP1 | 10383.0 |
| RPL19 | 10237.0 |
| RPL27A | 10126.0 |
| RPL38 | 10097.0 |
| RPS12 | 10065.0 |
| RPL27 | 10018.0 |
| RPL12 | 9972.0 |
| RPL5 | 9847.0 |
| RPL10A | 9823.0 |
| RPSA | 9598.0 |
| EEF1A1 | 9508.0 |
| RPL35A | 9504.0 |
| RPL13 | 9355.0 |
| RPL11 | 9263.0 |
| EEF1B2 | 9172.0 |
| RPL34 | 8949.0 |
| RPL36AL | 8546.5 |
| RPL18A | 8433.0 |
| RPS18 | 8418.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL39L | 10429.0 |
| RPLP1 | 10383.0 |
| RPL19 | 10237.0 |
| RPL27A | 10126.0 |
| RPL38 | 10097.0 |
| RPS12 | 10065.0 |
| RPL27 | 10018.0 |
| RPL12 | 9972.0 |
| RPL5 | 9847.0 |
| RPL10A | 9823.0 |
| RPSA | 9598.0 |
| EEF1A1 | 9508.0 |
| RPL35A | 9504.0 |
| RPL13 | 9355.0 |
| RPL11 | 9263.0 |
| EEF1B2 | 9172.0 |
| RPL34 | 8949.0 |
| RPL36AL | 8546.5 |
| RPL18A | 8433.0 |
| RPS18 | 8418.0 |
| RPL7 | 8407.0 |
| RPS14 | 8367.0 |
| RPL37 | 8126.0 |
| RPS28 | 8053.0 |
| RPL7A | 7958.0 |
| RPL23 | 7819.0 |
| RPL6 | 7585.0 |
| RPL28 | 7492.0 |
| RPLP0 | 7456.0 |
| RPS10 | 7422.0 |
| RPS9 | 7239.0 |
| RPL3 | 7066.0 |
| UBA52 | 6901.0 |
| RPL4 | 6839.0 |
| RPL23A | 6780.0 |
| RPS13 | 6745.0 |
| EEF1A2 | 6733.0 |
| RPL32 | 6717.0 |
| RPS21 | 6312.0 |
| RPS27A | 6223.0 |
| RPS23 | 6171.0 |
| RPS2 | 6145.0 |
| RPL8 | 6083.0 |
| RPS3A | 5876.0 |
| RPS27L | 5650.0 |
| RPS16 | 5552.0 |
| RPL15 | 5410.0 |
| FAU | 5376.0 |
| EEF1G | 5173.0 |
| RPL18 | 4825.0 |
| RPL26 | 4557.0 |
| RPL17 | 4473.0 |
| RPS11 | 4468.0 |
| RPL21 | 4396.0 |
| RPS20 | 4174.0 |
| RPS15A | 4169.0 |
| RPS8 | 4117.0 |
| RPL30 | 3957.0 |
| RPL26L1 | 3710.0 |
| RPS19 | 3558.0 |
| RPS5 | 3408.0 |
| RPS24 | 3357.0 |
| RPS7 | 3333.0 |
| RPL37A | 3063.0 |
| RPL22 | 2864.0 |
| RPS29 | 2812.0 |
| RPL35 | 2694.0 |
| RPS26 | 2583.0 |
| RPS27 | 2232.0 |
| RPS25 | 2059.0 |
| RPL22L1 | 1785.0 |
| RPS6 | 1237.0 |
| RPL24 | 901.0 |
| RPLP2 | 141.0 |
| RPL9 | -399.0 |
| RPL29 | -634.0 |
| RPL36 | -891.0 |
| RPS3 | -935.0 |
| RPL41 | -2639.0 |
| RPL13A | -2765.5 |
| RPS15 | -2768.0 |
| RPL31 | -3475.0 |
| EEF2 | -4923.0 |
| RPL14 | -5770.0 |
| EEF1D | -9713.0 |
| RPL3L | -10862.0 |
| RPL10L | -10981.0 |
REACTOME_NONSENSE_MEDIATED_DECAY_NMD
| 1443 | |
|---|---|
| set | REACTOME_NONSENSE_MEDIATED_DECAY_NMD |
| setSize | 107 |
| pANOVA | 1.14e-12 |
| s.dist | 0.398 |
| p.adjustANOVA | 1.88e-10 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL39L | 10429.0 |
| RPLP1 | 10383.0 |
| RPL19 | 10237.0 |
| RPL27A | 10126.0 |
| RPL38 | 10097.0 |
| RPS12 | 10065.0 |
| RPL27 | 10018.0 |
| RPL12 | 9972.0 |
| RPL5 | 9847.0 |
| RPL10A | 9823.0 |
| RPSA | 9598.0 |
| RPL35A | 9504.0 |
| RPL13 | 9355.0 |
| RPL11 | 9263.0 |
| RBM8A | 9093.0 |
| RPL34 | 8949.0 |
| ETF1 | 8741.0 |
| RPL36AL | 8546.5 |
| RPL18A | 8433.0 |
| RPS18 | 8418.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL39L | 10429.0 |
| RPLP1 | 10383.0 |
| RPL19 | 10237.0 |
| RPL27A | 10126.0 |
| RPL38 | 10097.0 |
| RPS12 | 10065.0 |
| RPL27 | 10018.0 |
| RPL12 | 9972.0 |
| RPL5 | 9847.0 |
| RPL10A | 9823.0 |
| RPSA | 9598.0 |
| RPL35A | 9504.0 |
| RPL13 | 9355.0 |
| RPL11 | 9263.0 |
| RBM8A | 9093.0 |
| RPL34 | 8949.0 |
| ETF1 | 8741.0 |
| RPL36AL | 8546.5 |
| RPL18A | 8433.0 |
| RPS18 | 8418.0 |
| RPL7 | 8407.0 |
| RPS14 | 8367.0 |
| RPL37 | 8126.0 |
| UPF2 | 8123.0 |
| RPS28 | 8053.0 |
| RPL7A | 7958.0 |
| RPL23 | 7819.0 |
| RPL6 | 7585.0 |
| RPL28 | 7492.0 |
| RPLP0 | 7456.0 |
| RPS10 | 7422.0 |
| RPS9 | 7239.0 |
| RPL3 | 7066.0 |
| UBA52 | 6901.0 |
| RPL4 | 6839.0 |
| RPL23A | 6780.0 |
| RPS13 | 6745.0 |
| RPL32 | 6717.0 |
| SMG1 | 6516.0 |
| RPS21 | 6312.0 |
| RPS27A | 6223.0 |
| RPS23 | 6171.0 |
| RPS2 | 6145.0 |
| RPL8 | 6083.0 |
| RPS3A | 5876.0 |
| RPS27L | 5650.0 |
| RPS16 | 5552.0 |
| RPL15 | 5410.0 |
| FAU | 5376.0 |
| RPL18 | 4825.0 |
| PNRC2 | 4795.0 |
| NCBP1 | 4593.0 |
| RPL26 | 4557.0 |
| RPL17 | 4473.0 |
| RPS11 | 4468.0 |
| RPL21 | 4396.0 |
| RPS20 | 4174.0 |
| RPS15A | 4169.0 |
| RPS8 | 4117.0 |
| RPL30 | 3957.0 |
| RPL26L1 | 3710.0 |
| SMG7 | 3596.0 |
| RPS19 | 3558.0 |
| RPS5 | 3408.0 |
| RPS24 | 3357.0 |
| RPS7 | 3333.0 |
| RPL37A | 3063.0 |
| RPL22 | 2864.0 |
| RPS29 | 2812.0 |
| RPL35 | 2694.0 |
| RPS26 | 2583.0 |
| RPS27 | 2232.0 |
| SMG6 | 2149.0 |
| RPS25 | 2059.0 |
| UPF3A | 1945.0 |
| SMG8 | 1902.0 |
| RPL22L1 | 1785.0 |
| MAGOH | 1757.0 |
| GSPT1 | 1694.0 |
| NCBP2 | 1556.0 |
| CASC3 | 1522.0 |
| RPS6 | 1237.0 |
| SMG9 | 1200.0 |
| RNPS1 | 1122.0 |
| DCP1A | 1119.0 |
| RPL24 | 901.0 |
| PABPC1 | 181.0 |
| EIF4G1 | 169.0 |
| PPP2R1A | 156.0 |
| RPLP2 | 141.0 |
| RPL9 | -399.0 |
| RPL29 | -634.0 |
| MAGOHB | -712.0 |
| RPL36 | -891.0 |
| UPF1 | -897.0 |
| RPS3 | -935.0 |
| PPP2CA | -1246.0 |
| RPL41 | -2639.0 |
| RPL13A | -2765.5 |
| RPS15 | -2768.0 |
| RPL31 | -3475.0 |
| SMG5 | -3786.0 |
| PPP2R2A | -4580.0 |
| RPL14 | -5770.0 |
| EIF4A3 | -8763.0 |
| RPL3L | -10862.0 |
| RPL10L | -10981.0 |
REACTOME_SENSORY_PERCEPTION
| 1581 | |
|---|---|
| set | REACTOME_SENSORY_PERCEPTION |
| setSize | 555 |
| pANOVA | 6.12e-12 |
| s.dist | -0.171 |
| p.adjustANOVA | 9.14e-10 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| OR8B4 | -11186.0 |
| OR1K1 | -11148.0 |
| TAS2R41 | -11099.0 |
| OR5M8 | -11065.0 |
| OR4K15 | -10962.0 |
| OR2S2 | -10961.0 |
| OR10Z1 | -10938.0 |
| TAS1R3 | -10916.0 |
| OR2T12 | -10858.0 |
| OR1L8 | -10789.0 |
| OR7E24 | -10785.5 |
| OR5C1 | -10781.0 |
| TAS2R31 | -10761.0 |
| OR6Y1 | -10749.0 |
| OR4D5 | -10731.0 |
| OR51G2 | -10669.0 |
| CHRNA10 | -10664.0 |
| GNB3 | -10659.0 |
| OR10C1 | -10643.0 |
| STRA6 | -10606.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| OR8B4 | -11186.0 |
| OR1K1 | -11148.0 |
| TAS2R41 | -11099.0 |
| OR5M8 | -11065.0 |
| OR4K15 | -10962.0 |
| OR2S2 | -10961.0 |
| OR10Z1 | -10938.0 |
| TAS1R3 | -10916.0 |
| OR2T12 | -10858.0 |
| OR1L8 | -10789.0 |
| OR7E24 | -10785.5 |
| OR5C1 | -10781.0 |
| TAS2R31 | -10761.0 |
| OR6Y1 | -10749.0 |
| OR4D5 | -10731.0 |
| OR51G2 | -10669.0 |
| CHRNA10 | -10664.0 |
| GNB3 | -10659.0 |
| OR10C1 | -10643.0 |
| STRA6 | -10606.0 |
| OR14A16 | -10596.0 |
| OR52E2 | -10589.0 |
| OR10J3 | -10547.0 |
| OR1N1 | -10542.0 |
| GRK1 | -10465.0 |
| OR10K2 | -10447.0 |
| APOA2 | -10433.0 |
| AKR1B10 | -10428.0 |
| OR52D1 | -10416.0 |
| OR4E2 | -10401.0 |
| CLPS | -10396.0 |
| OR8A1 | -10334.0 |
| CALHM3 | -10302.0 |
| CHRNA9 | -10272.0 |
| MYO15A | -10270.0 |
| OR52A5 | -10261.5 |
| OR52L1 | -10250.0 |
| OR13J1 | -10213.0 |
| CNGB1 | -10188.0 |
| OR2G2 | -10183.0 |
| TAS2R30 | -10179.0 |
| LRP8 | -10176.0 |
| OR52R1 | -10163.0 |
| GRK7 | -10150.0 |
| OR13C2 | -10111.0 |
| OPN1SW | -10103.0 |
| OR2T1 | -10057.0 |
| TAS2R20 | -10049.0 |
| OR1J4 | -10042.0 |
| OR2G3 | -10029.0 |
| AKR1C4 | -9961.0 |
| OR2L5 | -9940.0 |
| OR9I1 | -9840.0 |
| OR10A3 | -9825.0 |
| RBP2 | -9785.0 |
| RLBP1 | -9766.0 |
| OR8K3 | -9752.0 |
| APOC3 | -9717.0 |
| TAS2R10 | -9684.0 |
| RBP3 | -9675.0 |
| TAS2R3 | -9663.0 |
| OR2A14 | -9641.0 |
| CABP2 | -9569.0 |
| TRPM5 | -9557.0 |
| OR51E1 | -9509.0 |
| OR4A5 | -9480.0 |
| GPIHBP1 | -9457.0 |
| AGRN | -9394.0 |
| OR5K1 | -9392.0 |
| OR6C65 | -9374.0 |
| OR5B21 | -9372.0 |
| OR52J3 | -9371.0 |
| CALHM1 | -9351.0 |
| RHO | -9332.0 |
| OR1G1 | -9308.0 |
| OR7D4 | -9301.0 |
| ADCY3 | -9298.0 |
| OR2W3 | -9288.0 |
| OR51I2 | -9282.0 |
| OR3A1 | -9211.0 |
| OR11L1 | -9195.0 |
| OR8D1 | -9117.0 |
| OR2M4 | -9065.0 |
| OR51F1 | -9055.0 |
| OR52H1 | -9028.0 |
| OR11H6 | -9023.0 |
| KCNQ4 | -8887.0 |
| GPC1 | -8827.0 |
| OTOG | -8823.0 |
| OR6M1 | -8809.0 |
| SCNN1D | -8788.0 |
| LRP1 | -8769.0 |
| OR7G1 | -8736.0 |
| OR4K5 | -8706.0 |
| OR2Y1 | -8697.0 |
| OR8B2 | -8695.0 |
| CACNA2D2 | -8692.0 |
| OR10H1 | -8684.0 |
| PDE6G | -8677.0 |
| ITPR3 | -8659.0 |
| CNGA1 | -8626.0 |
| OR56A3 | -8621.0 |
| OR2F2 | -8607.0 |
| BSN | -8540.0 |
| OR6T1 | -8527.0 |
| HSPG2 | -8522.0 |
| OR52A1 | -8517.0 |
| RTP1 | -8482.0 |
| OR2AG2 | -8441.0 |
| OTOF | -8438.0 |
| OR52E6 | -8377.0 |
| OR6C68 | -8368.0 |
| OR51B4 | -8366.0 |
| OR52B6 | -8334.0 |
| RDH5 | -8330.0 |
| TRIOBP | -8301.0 |
| OR13F1 | -8275.0 |
| OR12D3 | -8241.0 |
| TAS2R46 | -8229.0 |
| OR1N2 | -8223.0 |
| TWF2 | -8150.0 |
| OR6C1 | -8140.0 |
| TAS2R5 | -8136.0 |
| RTP2 | -8123.0 |
| OR51I1 | -8087.0 |
| OR8B8 | -8081.0 |
| FNTA | -8045.0 |
| OR1L1 | -7980.0 |
| OR4D10 | -7975.0 |
| MYO1C | -7966.0 |
| OR13G1 | -7921.0 |
| TRPM4 | -7899.0 |
| EPB41L1 | -7791.0 |
| OR8D2 | -7746.0 |
| ATP2B2 | -7730.0 |
| TAS2R39 | -7718.0 |
| OR5J2 | -7715.0 |
| OR51G1 | -7708.0 |
| SAG | -7694.0 |
| OR10K1 | -7675.0 |
| GUCA1A | -7642.0 |
| OR2T8 | -7631.0 |
| OR11A1 | -7622.0 |
| OR6C75 | -7609.0 |
| OR1L6 | -7571.0 |
| OR5M3 | -7531.0 |
| APOA4 | -7472.0 |
| HSD17B6 | -7455.0 |
| TAS2R4 | -7407.0 |
| OR14I1 | -7384.0 |
| CIB2 | -7375.0 |
| OR52K2 | -7353.0 |
| OR1Q1 | -7304.0 |
| APOM | -7296.0 |
| OR1M1 | -7295.0 |
| OR5P3 | -7262.0 |
| OR5K2 | -7218.0 |
| OR11G2 | -7192.0 |
| WHRN | -7165.0 |
| OR10A5 | -7159.0 |
| OR2B11 | -7134.0 |
| GRM4 | -7118.0 |
| OR5F1 | -7086.0 |
| FNTB | -7073.0 |
| OR2AP1 | -7063.0 |
| LHFPL5 | -7048.0 |
| OR8J3 | -7021.0 |
| OR1L4 | -6997.0 |
| SDC4 | -6994.0 |
| GNAT3 | -6883.0 |
| CNGA4 | -6855.0 |
| OR8J1 | -6843.0 |
| HSD17B1 | -6836.0 |
| OR13C8 | -6806.0 |
| OR4L1 | -6795.0 |
| OR6C3 | -6790.0 |
| OR4K1 | -6764.0 |
| GUCA1B | -6729.0 |
| LDLR | -6685.0 |
| OR10V1 | -6629.0 |
| OR51B2 | -6597.0 |
| OR51F2 | -6578.0 |
| OR52B2 | -6547.0 |
| OR2T6 | -6536.0 |
| OR4F15 | -6481.0 |
| GRXCR2 | -6459.0 |
| OR4M1 | -6438.0 |
| PDE6B | -6423.0 |
| OR6C70 | -6391.0 |
| SPTAN1 | -6341.0 |
| OR7C2 | -6339.0 |
| SCN4B | -6283.0 |
| EPB41L3 | -6224.0 |
| OR52I2 | -6192.0 |
| OR5T1 | -6188.0 |
| OR5M10 | -6180.0 |
| OR8H3 | -6171.0 |
| CDH23 | -6136.0 |
| KCNMB1 | -6101.0 |
| OR4N5 | -6088.0 |
| CLIC5 | -6077.0 |
| OR8K5 | -6074.0 |
| PLCB2 | -6032.0 |
| TAS2R8 | -6019.0 |
| OR5L2 | -5998.0 |
| OR51M1 | -5996.0 |
| OR1C1 | -5930.0 |
| OR51S1 | -5865.0 |
| OR2A12 | -5841.0 |
| TAS2R50 | -5798.0 |
| OR4S1 | -5779.0 |
| LRP10 | -5698.0 |
| OR13C3 | -5597.0 |
| OR5AC2 | -5593.0 |
| CTBP2 | -5508.0 |
| OR5D18 | -5465.0 |
| OR7C1 | -5464.0 |
| OR52M1 | -5412.0 |
| TMC1 | -5391.0 |
| DHRS3 | -5287.0 |
| NAPEPLD | -5282.0 |
| OR4C3 | -5278.5 |
| NMT1 | -5155.0 |
| OR2V2 | -5118.0 |
| OR5V1 | -5093.0 |
| SDC1 | -5052.0 |
| OR5B2 | -5029.0 |
| OR10S1 | -5020.0 |
| OR5AR1 | -4978.0 |
| GNB1 | -4968.0 |
| TAS2R14 | -4911.0 |
| OR51E2 | -4871.0 |
| OR2Z1 | -4841.0 |
| OR6F1 | -4755.0 |
| OR2M3 | -4751.0 |
| SLC24A1 | -4736.0 |
| OR10H2 | -4681.0 |
| OR9Q1 | -4658.0 |
| SCN2A | -4639.0 |
| OR10A2 | -4634.0 |
| GPC2 | -4616.0 |
| OR56A5 | -4614.0 |
| GUCY2D | -4602.0 |
| OR2J2 | -4588.0 |
| OR5K4 | -4572.0 |
| TAS1R1 | -4506.0 |
| MYO7A | -4494.0 |
| OR5T2 | -4479.0 |
| OR5M1 | -4443.0 |
| OR6S1 | -4441.0 |
| OR52E8 | -4411.0 |
| OR2A5 | -4392.0 |
| ESPNL | -4391.0 |
| OR10G4 | -4318.0 |
| OR5AN1 | -4222.0 |
| OR6X1 | -4214.0 |
| OR1D2 | -4209.0 |
| CAPZA2 | -4200.0 |
| OR51V1 | -4184.0 |
| OR6K2 | -4172.0 |
| OR4D1 | -4092.0 |
| RGS9 | -4049.0 |
| GNGT1 | -3999.0 |
| USH1C | -3974.0 |
| OR8U3 | -3922.0 |
| OR10A4 | -3822.0 |
| OR5B3 | -3818.0 |
| SCN3A | -3811.0 |
| OR4K2 | -3731.0 |
| PRKCA | -3721.0 |
| OR1J2 | -3701.0 |
| OR4D2 | -3646.0 |
| OR1I1 | -3555.0 |
| OR5W2 | -3539.0 |
| PNLIP | -3502.0 |
| OR9G4 | -3488.0 |
| CALM1 | -3487.0 |
| LRP12 | -3440.0 |
| TAS2R16 | -3386.0 |
| OR2G6 | -3349.0 |
| TMIE | -3328.0 |
| ABCA4 | -3302.0 |
| OR51T1 | -3301.0 |
| OR10AD1 | -3280.0 |
| OR6C2 | -3279.0 |
| OR1B1 | -3184.0 |
| CACNA1D | -3183.0 |
| RDH12 | -3175.0 |
| OR4C6 | -3021.0 |
| OR2D3 | -3002.0 |
| KCNMA1 | -2962.0 |
| OR5L1 | -2959.0 |
| OR5AP2 | -2953.0 |
| OR56B1 | -2948.0 |
| OR7G2 | -2920.0 |
| ATP2B1 | -2912.0 |
| OR51D1 | -2826.0 |
| OR10G7 | -2785.0 |
| OR51Q1 | -2721.0 |
| OR6Q1 | -2714.0 |
| OR10H3 | -2712.0 |
| OR52N2 | -2641.0 |
| OR8G1 | -2554.0 |
| APOB | -2506.0 |
| OR8U8 | -2383.0 |
| OR14C36 | -2348.0 |
| RDH16 | -2313.0 |
| OR2D2 | -2288.0 |
| OR1E1 | -2260.0 |
| RBP4 | -2244.0 |
| OR10X1 | -2204.0 |
| RPE65 | -2167.0 |
| OR8H1 | -2076.0 |
| APOA1 | -2062.0 |
| OR51B5 | -1934.0 |
| SCNN1B | -1890.0 |
| OR4C45 | -1868.0 |
| OR2C1 | -1865.0 |
| OR10H4 | -1850.0 |
| OR4A16 | -1830.0 |
| OR5D16 | -1817.0 |
| OR10P1 | -1771.0 |
| OR51L1 | -1745.0 |
| OR6N1 | -1718.0 |
| OR9A2 | -1711.0 |
| OR5B12 | -1660.0 |
| OR6A2 | -1604.0 |
| OR5M9 | -1570.0 |
| OR2C3 | -1562.0 |
| OR4C15 | -1495.0 |
| OR13A1 | -1408.0 |
| DNAJC5 | -1344.0 |
| OR5M11 | -1257.0 |
| OR6V1 | -1018.0 |
| OR4X1 | -999.0 |
| OR7G3 | -996.0 |
| TPRN | -959.0 |
| EZR | -937.0 |
| OR2K2 | -931.0 |
| TAS2R7 | -922.0 |
| TAS2R1 | -878.0 |
| OR7D2 | -835.0 |
| OR2T3 | -828.0 |
| GRK4 | -825.0 |
| AKR1C3 | -749.0 |
| SCNN1A | -696.0 |
| OR7A5 | -690.0 |
| OR52K1 | -653.0 |
| PLB1 | -643.0 |
| NMT2 | -564.0 |
| RCVRN | -537.0 |
| OR52N1 | -490.0 |
| OR2H1 | -413.0 |
| OR2L13 | -321.0 |
| PLS1 | -273.0 |
| OR12D2 | -207.0 |
| CACNB2 | -166.0 |
| GNB5 | -74.0 |
| OR51B6 | -37.0 |
| CAMKMT | -14.0 |
| OR2M5 | 38.0 |
| OR4X2 | 87.0 |
| OR10H5 | 237.0 |
| OR10Q1 | 260.0 |
| GPC6 | 308.0 |
| OR9G1 | 323.5 |
| OR9G9 | 323.5 |
| SNAP25 | 361.0 |
| PDE6A | 489.0 |
| OR8U1 | 492.0 |
| GNAL | 502.0 |
| SPTBN1 | 561.0 |
| GSN | 575.0 |
| RDH11 | 587.0 |
| PCLO | 673.0 |
| MYH9 | 748.0 |
| XIRP2 | 839.0 |
| LPL | 937.0 |
| FSCN2 | 971.0 |
| GPC5 | 1032.0 |
| EPS8 | 1123.0 |
| OR2L8 | 1273.0 |
| OR2F1 | 1280.0 |
| OR3A3 | 1284.0 |
| OR2AE1 | 1390.0 |
| TAS1R2 | 1473.0 |
| GRXCR1 | 1534.0 |
| OR9Q2 | 1552.0 |
| OR13D1 | 1649.0 |
| LRP2 | 1708.0 |
| OR4K17 | 1777.0 |
| PCDH15 | 1839.0 |
| OR5H6 | 1918.0 |
| STX1A | 1966.0 |
| OR4C16 | 1992.0 |
| BCO1 | 2023.0 |
| VAMP2 | 2227.0 |
| OR56A1 | 2257.0 |
| GNG13 | 2324.0 |
| SDC3 | 2347.0 |
| OR4D11 | 2396.0 |
| EBF1 | 2412.0 |
| SCNN1G | 2418.0 |
| MYO3B | 2445.0 |
| APOC2 | 2469.0 |
| OR4C12 | 2496.0 |
| EPS8L2 | 2558.0 |
| CAPZB | 2596.0 |
| OR2B3 | 2637.0 |
| OR6B3 | 2641.0 |
| SCN2B | 2752.0 |
| OR1S1 | 2819.0 |
| OR6K6 | 2904.0 |
| OR1F1 | 2933.0 |
| RGS9BP | 3035.0 |
| OR52I1 | 3060.0 |
| OR5AS1 | 3082.0 |
| OR5P2 | 3105.0 |
| OR7A17 | 3250.0 |
| RIPOR2 | 3279.0 |
| ACTG1 | 3324.0 |
| BCO2 | 3342.0 |
| OR6N2 | 3377.0 |
| SCN1B | 3390.0 |
| OR6P1 | 3439.0 |
| CABP1 | 3555.0 |
| GUCA1C | 3557.0 |
| USH1G | 3559.0 |
| OR52W1 | 3584.0 |
| OR5I1 | 3604.0 |
| OR11H4 | 3639.0 |
| OR10G8 | 3813.0 |
| OR5A1 | 3818.0 |
| REEP1 | 3830.0 |
| OR1L3 | 3891.0 |
| OR5AU1 | 3922.0 |
| GNAT1 | 4010.0 |
| OR10A6 | 4052.0 |
| OTOGL | 4125.0 |
| OR4B1 | 4145.0 |
| OR2M7 | 4292.0 |
| RDX | 4423.0 |
| ANO2 | 4431.0 |
| OR6C74 | 4462.0 |
| LHX2 | 4657.0 |
| OR4N2 | 4702.0 |
| TTR | 4713.0 |
| RDH10 | 4819.0 |
| ESPN | 4909.0 |
| SDC2 | 4916.0 |
| LRAT | 4936.0 |
| TAS2R40 | 5006.0 |
| OR4A15 | 5167.0 |
| PRKCQ | 5380.0 |
| DHRS9 | 5539.0 |
| OR2T27 | 5572.0 |
| OR10A7 | 5629.0 |
| OR8S1 | 5659.0 |
| OR10G3 | 5673.0 |
| METAP1 | 5737.0 |
| OR9K2 | 5767.0 |
| OR8K1 | 5793.0 |
| OR2W1 | 5824.0 |
| MYO3A | 5833.0 |
| OR6C76 | 5857.0 |
| PJVK | 5886.0 |
| RAB3A | 5968.0 |
| OR13C9 | 6007.0 |
| OR5AK2 | 6054.0 |
| TWF1 | 6128.0 |
| OR2L2 | 6139.0 |
| CAPZA1 | 6183.0 |
| GRM1 | 6210.0 |
| OR1A1 | 6295.0 |
| OR52E4 | 6453.0 |
| OR51A7 | 6507.0 |
| RBP1 | 6557.0 |
| OR2AK2 | 6602.0 |
| OR14J1 | 6618.0 |
| OR7A10 | 6647.0 |
| OR56B4 | 6666.0 |
| STRC | 6728.0 |
| RDH8 | 6770.0 |
| APOE | 6838.0 |
| METAP2 | 6880.0 |
| OR5D14 | 6986.0 |
| OR10W1 | 7040.0 |
| CYP4V2 | 7064.0 |
| SCN9A | 7129.0 |
| TAS2R13 | 7144.0 |
| OR6C4 | 7379.0 |
| SLC26A5 | 7398.0 |
| KCNJ2 | 7402.0 |
| OR9A4 | 7471.0 |
| OR8G5 | 7824.0 |
| OR3A2 | 7848.0 |
| OR4K14 | 7932.0 |
| LDB1 | 8039.0 |
| TMC2 | 8058.0 |
| TAS2R38 | 8135.0 |
| RETSAT | 8400.0 |
| OR2T11 | 8494.0 |
| OR2T33 | 8542.0 |
| OR13C4 | 8683.0 |
| OR5K3 | 8799.0 |
| OR10G2 | 8843.0 |
| OR51A2 | 8904.0 |
| OR4F6 | 8953.0 |
| ACTB | 8973.0 |
| SDR9C7 | 9007.0 |
| OR6B2 | 9035.0 |
| TAS2R43 | 9103.0 |
| OR1J1 | 9227.0 |
| OR8D4 | 9261.0 |
| OR10J1 | 9275.0 |
| OR1S2 | 9350.0 |
| OR2T4 | 9374.0 |
| OR2A2 | 9387.0 |
| KCNN2 | 9468.0 |
| OR2B2 | 9550.0 |
| AKR1C1 | 9567.0 |
| OR2H2 | 9668.0 |
| OR10AG1 | 9689.0 |
| OR5H1 | 9730.0 |
| OR6B1 | 9744.0 |
| OR5A2 | 9746.0 |
| OR4D6 | 9821.0 |
| OR1A2 | 9949.0 |
| OR5H15 | 9987.0 |
| OR2AG1 | 10002.0 |
| OR2V1 | 10004.0 |
| SLC17A8 | 10036.0 |
| LRRC52 | 10105.0 |
| OR5D13 | 10163.0 |
| OTOP1 | 10166.0 |
| OR5H2 | 10198.0 |
| OR6C6 | 10204.0 |
| OR56A4 | 10212.0 |
| OR1E2 | 10214.0 |
| OR10J5 | 10312.0 |
| OR4A47 | 10336.0 |
| OR10T2 | 10343.0 |
| OR2L3 | 10354.0 |
| OR5T3 | 10357.0 |
| OR2AT4 | 10394.0 |
| OR2M2 | 10398.0 |
| OR8B12 | 10421.0 |
| OR4C46 | 10425.0 |
| OR4D9 | 10485.0 |
| OR2B6 | 10514.0 |
| OR4K13 | 10515.0 |
| OR6K3 | 10535.0 |
| OR10G9 | 10536.0 |
| OR5B17 | 10574.0 |
| OR8I2 | 10622.0 |
REACTOME_SIGNALING_BY_ROBO_RECEPTORS
| 605 | |
|---|---|
| set | REACTOME_SIGNALING_BY_ROBO_RECEPTORS |
| setSize | 206 |
| pANOVA | 4.62e-11 |
| s.dist | 0.266 |
| p.adjustANOVA | 6.32e-09 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL39L | 10429 |
| RPLP1 | 10383 |
| UBB | 10269 |
| RPL19 | 10237 |
| RPL27A | 10126 |
| RPL38 | 10097 |
| RPS12 | 10065 |
| RPL27 | 10018 |
| RPL12 | 9972 |
| RPL5 | 9847 |
| RPL10A | 9823 |
| RPSA | 9598 |
| VASP | 9510 |
| RPL35A | 9504 |
| RPL13 | 9355 |
| PSMB3 | 9282 |
| RPL11 | 9263 |
| RBM8A | 9093 |
| PSMA6 | 9088 |
| RPL34 | 8949 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL39L | 10429.0 |
| RPLP1 | 10383.0 |
| UBB | 10269.0 |
| RPL19 | 10237.0 |
| RPL27A | 10126.0 |
| RPL38 | 10097.0 |
| RPS12 | 10065.0 |
| RPL27 | 10018.0 |
| RPL12 | 9972.0 |
| RPL5 | 9847.0 |
| RPL10A | 9823.0 |
| RPSA | 9598.0 |
| VASP | 9510.0 |
| RPL35A | 9504.0 |
| RPL13 | 9355.0 |
| PSMB3 | 9282.0 |
| RPL11 | 9263.0 |
| RBM8A | 9093.0 |
| PSMA6 | 9088.0 |
| RPL34 | 8949.0 |
| PSMA7 | 8947.0 |
| ETF1 | 8741.0 |
| PSME2 | 8738.0 |
| PSMC5 | 8695.0 |
| UBC | 8680.0 |
| PSMA1 | 8676.0 |
| CXCR4 | 8652.0 |
| PFN1 | 8580.0 |
| RPL36AL | 8546.5 |
| ISL1 | 8475.0 |
| RPL18A | 8433.0 |
| RPS18 | 8418.0 |
| RPL7 | 8407.0 |
| PSMD12 | 8377.0 |
| RPS14 | 8367.0 |
| PSMB1 | 8157.0 |
| RPL37 | 8126.0 |
| UPF2 | 8123.0 |
| RPS28 | 8053.0 |
| PSMC4 | 8042.0 |
| LDB1 | 8039.0 |
| RPL7A | 7958.0 |
| RPL23 | 7819.0 |
| LHX9 | 7783.0 |
| RPL6 | 7585.0 |
| ELOC | 7494.0 |
| RPL28 | 7492.0 |
| RPLP0 | 7456.0 |
| RPS10 | 7422.0 |
| DCC | 7266.0 |
| RPS9 | 7239.0 |
| PSMB9 | 7201.0 |
| RAC1 | 7075.0 |
| RPL3 | 7066.0 |
| CAP2 | 7057.0 |
| CAP1 | 7031.0 |
| UBA52 | 6901.0 |
| RPL4 | 6839.0 |
| RPL23A | 6780.0 |
| RPS13 | 6745.0 |
| RPL32 | 6717.0 |
| NELL2 | 6605.0 |
| ROBO3 | 6480.0 |
| PRKAR2A | 6454.0 |
| RPS21 | 6312.0 |
| PSMB7 | 6283.0 |
| RPS27A | 6223.0 |
| PSMB10 | 6211.0 |
| RPS23 | 6171.0 |
| RPS2 | 6145.0 |
| RPL8 | 6083.0 |
| PSMB8 | 6003.0 |
| PSMD13 | 5916.0 |
| RPS3A | 5876.0 |
| RPS27L | 5650.0 |
| RPS16 | 5552.0 |
| PSMC6 | 5420.0 |
| RPL15 | 5410.0 |
| FAU | 5376.0 |
| LHX4 | 5348.0 |
| PSMA4 | 4963.0 |
| PSMD7 | 4932.0 |
| SOS2 | 4905.0 |
| RPL18 | 4825.0 |
| LHX2 | 4657.0 |
| NCBP1 | 4593.0 |
| RPL26 | 4557.0 |
| RPL17 | 4473.0 |
| RPS11 | 4468.0 |
| RPL21 | 4396.0 |
| ELOB | 4304.0 |
| RPS20 | 4174.0 |
| RPS15A | 4169.0 |
| RPS8 | 4117.0 |
| PSMA3 | 4116.0 |
| RPL30 | 3957.0 |
| RBX1 | 3880.0 |
| RPL26L1 | 3710.0 |
| RPS19 | 3558.0 |
| CXCL12 | 3549.0 |
| PAK5 | 3471.0 |
| RPS5 | 3408.0 |
| RPS24 | 3357.0 |
| RPS7 | 3333.0 |
| PSMB2 | 3326.0 |
| RPL37A | 3063.0 |
| PSMB4 | 3049.0 |
| PSMC1 | 2987.0 |
| RPL22 | 2864.0 |
| RPS29 | 2812.0 |
| RPL35 | 2694.0 |
| RPS26 | 2583.0 |
| PPP3CB | 2472.0 |
| SLIT2 | 2470.0 |
| PSMA8 | 2379.0 |
| PFN2 | 2269.0 |
| RPS27 | 2232.0 |
| PSMD1 | 2144.0 |
| PSME4 | 2128.0 |
| USP33 | 2079.0 |
| PSMB5 | 2078.0 |
| RPS25 | 2059.0 |
| UPF3A | 1945.0 |
| PRKACB | 1818.0 |
| RPL22L1 | 1785.0 |
| MAGOH | 1757.0 |
| PSMC3 | 1749.0 |
| GSPT1 | 1694.0 |
| FLRT3 | 1659.0 |
| SEM1 | 1657.0 |
| PSMC2 | 1653.0 |
| NCBP2 | 1556.0 |
| CASC3 | 1522.0 |
| CLASP2 | 1411.0 |
| PSMD4 | 1403.0 |
| ROBO1 | 1340.0 |
| RPS6 | 1237.0 |
| RNPS1 | 1122.0 |
| RPL24 | 901.0 |
| NCK2 | 677.0 |
| PSMA5 | 665.0 |
| ABL1 | 607.0 |
| PSMA2 | 467.0 |
| PSMD3 | 274.0 |
| ENAH | 193.0 |
| PABPC1 | 181.0 |
| EIF4G1 | 169.0 |
| RPLP2 | 141.0 |
| PSMD14 | -192.0 |
| RPL9 | -399.0 |
| PSME3 | -576.0 |
| RPL29 | -634.0 |
| MAGOHB | -712.0 |
| ABL2 | -839.0 |
| PSME1 | -840.0 |
| RPL36 | -891.0 |
| RPS3 | -935.0 |
| PSMD6 | -1076.0 |
| PSMD11 | -1095.0 |
| NCK1 | -1237.0 |
| PSMD5 | -1600.0 |
| PSMD8 | -1715.0 |
| PSMD9 | -1897.0 |
| PAK1 | -1927.0 |
| SRGAP3 | -2416.0 |
| SLIT3 | -2619.0 |
| RPL41 | -2639.0 |
| AKAP5 | -2760.0 |
| RPL13A | -2765.5 |
| RPS15 | -2768.0 |
| LHX3 | -3024.0 |
| CLASP1 | -3176.0 |
| EVL | -3424.0 |
| RPL31 | -3475.0 |
| PRKCA | -3721.0 |
| NRP1 | -4010.0 |
| PSMF1 | -4178.0 |
| PAK6 | -4516.0 |
| NTN1 | -4949.0 |
| SRGAP1 | -5058.0 |
| PAK2 | -5084.0 |
| PSMB6 | -5356.0 |
| SOS1 | -5362.0 |
| SLIT1 | -5446.0 |
| CDC42 | -5666.0 |
| RPL14 | -5770.0 |
| CUL2 | -5892.0 |
| ROBO2 | -5921.0 |
| PSMD2 | -6144.0 |
| PRKACA | -6164.0 |
| MYO9B | -6214.0 |
| MSI1 | -6307.0 |
| ARHGAP39 | -6385.0 |
| RHOA | -6611.0 |
| SRGAP2 | -6758.0 |
| DAG1 | -7442.0 |
| HOXA2 | -7605.0 |
| EIF4A3 | -8763.0 |
| GPC1 | -8827.0 |
| PRKACG | -8839.0 |
| PAK4 | -9278.0 |
| SRC | -9360.0 |
| ZSWIM8 | -9658.0 |
| PSMB11 | -10657.0 |
| RPL3L | -10862.0 |
| RPL10L | -10981.0 |
REACTOME_INFLUENZA_INFECTION
| 228 | |
|---|---|
| set | REACTOME_INFLUENZA_INFECTION |
| setSize | 149 |
| pANOVA | 9.77e-11 |
| s.dist | 0.307 |
| p.adjustANOVA | 1.23e-08 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL39L | 10429 |
| RPLP1 | 10383 |
| RPL19 | 10237 |
| RPL27A | 10126 |
| RPL38 | 10097 |
| RPS12 | 10065 |
| RPL27 | 10018 |
| RPL12 | 9972 |
| RPL5 | 9847 |
| RPL10A | 9823 |
| RPSA | 9598 |
| RPL35A | 9504 |
| CALR | 9479 |
| TPR | 9369 |
| RPL13 | 9355 |
| NUP35 | 9338 |
| RPL11 | 9263 |
| NUP107 | 9241 |
| RPL34 | 8949 |
| POLR2L | 8803 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL39L | 10429.0 |
| RPLP1 | 10383.0 |
| RPL19 | 10237.0 |
| RPL27A | 10126.0 |
| RPL38 | 10097.0 |
| RPS12 | 10065.0 |
| RPL27 | 10018.0 |
| RPL12 | 9972.0 |
| RPL5 | 9847.0 |
| RPL10A | 9823.0 |
| RPSA | 9598.0 |
| RPL35A | 9504.0 |
| CALR | 9479.0 |
| TPR | 9369.0 |
| RPL13 | 9355.0 |
| NUP35 | 9338.0 |
| RPL11 | 9263.0 |
| NUP107 | 9241.0 |
| RPL34 | 8949.0 |
| POLR2L | 8803.0 |
| NUP43 | 8731.0 |
| RPL36AL | 8546.5 |
| POLR2D | 8521.0 |
| POLR2C | 8482.0 |
| CANX | 8449.0 |
| RPL18A | 8433.0 |
| RPS18 | 8418.0 |
| RPL7 | 8407.0 |
| RPS14 | 8367.0 |
| NUP153 | 8165.0 |
| RPL37 | 8126.0 |
| HSPA1A | 8066.0 |
| RPS28 | 8053.0 |
| RPL7A | 7958.0 |
| RPL23 | 7819.0 |
| POLR2I | 7672.0 |
| NUP155 | 7642.0 |
| RPL6 | 7585.0 |
| XPO1 | 7555.0 |
| RPL28 | 7492.0 |
| RPLP0 | 7456.0 |
| RPS10 | 7422.0 |
| POLR2H | 7324.0 |
| RPS9 | 7239.0 |
| RPL3 | 7066.0 |
| UBA52 | 6901.0 |
| RPL4 | 6839.0 |
| RPL23A | 6780.0 |
| RPS13 | 6745.0 |
| RPL32 | 6717.0 |
| RPS21 | 6312.0 |
| RPS27A | 6223.0 |
| RPS23 | 6171.0 |
| RPS2 | 6145.0 |
| RPL8 | 6083.0 |
| POLR2E | 6038.0 |
| KPNB1 | 5984.0 |
| RPS3A | 5876.0 |
| NUP54 | 5663.0 |
| RPS27L | 5650.0 |
| RPS16 | 5552.0 |
| NUP50 | 5527.0 |
| KPNA3 | 5474.0 |
| RPL15 | 5410.0 |
| FAU | 5376.0 |
| POLR2K | 5369.0 |
| RPL18 | 4825.0 |
| RPL26 | 4557.0 |
| RPL17 | 4473.0 |
| RPS11 | 4468.0 |
| PARP1 | 4427.0 |
| RPL21 | 4396.0 |
| POM121 | 4393.0 |
| CLTA | 4366.0 |
| RPS20 | 4174.0 |
| RPS15A | 4169.0 |
| RPS8 | 4117.0 |
| RPL30 | 3957.0 |
| POM121C | 3776.0 |
| RPL26L1 | 3710.0 |
| RAN | 3664.0 |
| RPS19 | 3558.0 |
| NUP133 | 3422.0 |
| RPS5 | 3408.0 |
| RPS24 | 3357.0 |
| RPS7 | 3333.0 |
| NUP205 | 3185.0 |
| RPL37A | 3063.0 |
| RPL22 | 2864.0 |
| RPS29 | 2812.0 |
| CLTC | 2808.0 |
| RPL35 | 2694.0 |
| RPS26 | 2583.0 |
| NDC1 | 2410.0 |
| RPS27 | 2232.0 |
| POLR2G | 2138.0 |
| RPS25 | 2059.0 |
| HSP90AA1 | 2049.0 |
| RPL22L1 | 1785.0 |
| NUP88 | 1277.0 |
| RPS6 | 1237.0 |
| RAE1 | 1215.0 |
| RANBP2 | 1191.0 |
| KPNA7 | 1102.0 |
| RPL24 | 901.0 |
| KPNA4 | 895.0 |
| NUP160 | 618.0 |
| NUP98 | 368.0 |
| RPLP2 | 141.0 |
| KPNA5 | -359.0 |
| RPL9 | -399.0 |
| RPL29 | -634.0 |
| SEH1L | -682.0 |
| RPL36 | -891.0 |
| RPS3 | -935.0 |
| KPNA2 | -967.0 |
| NUP42 | -1128.0 |
| NUP37 | -1790.0 |
| GTF2F1 | -1794.0 |
| SEC13 | -2354.0 |
| GTF2F2 | -2395.0 |
| TGFB1 | -2596.0 |
| RPL41 | -2639.0 |
| RPL13A | -2765.5 |
| RPS15 | -2768.0 |
| EIF2AK2 | -2770.0 |
| ISG15 | -3143.0 |
| KPNA1 | -3299.0 |
| RPL31 | -3475.0 |
| POLR2B | -3675.0 |
| GRSF1 | -4457.0 |
| PABPN1 | -4462.0 |
| NUP214 | -4467.0 |
| NUP93 | -5201.0 |
| POLR2F | -5251.0 |
| RPL14 | -5770.0 |
| NUP62 | -6129.0 |
| IPO5 | -7010.0 |
| CPSF4 | -7119.0 |
| NUP188 | -7120.0 |
| NUP58 | -7794.0 |
| POLR2A | -8208.0 |
| NUP85 | -8221.0 |
| AAAS | -8286.0 |
| NUP210 | -8505.0 |
| DNAJC3 | -9484.0 |
| RPL3L | -10862.0 |
| POLR2J | -10901.0 |
| RPL10L | -10981.0 |
REACTOME_INFECTIOUS_DISEASE
| 974 | |
|---|---|
| set | REACTOME_INFECTIOUS_DISEASE |
| setSize | 910 |
| pANOVA | 1.26e-10 |
| s.dist | 0.126 |
| p.adjustANOVA | 1.48e-08 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TUBB8 | 10619 |
| GNGT2 | 10606 |
| TUBB4B | 10587 |
| IFNA1 | 10538 |
| CD8B | 10454 |
| RPL39L | 10429 |
| IFNA8 | 10386 |
| RPLP1 | 10383 |
| CTSG | 10382 |
| UBB | 10269 |
| IFNA16 | 10244 |
| RPL19 | 10237 |
| H3C12 | 10132 |
| RPL27A | 10126 |
| NOXO1 | 10107 |
| RPL38 | 10097 |
| RPS12 | 10065 |
| RPL27 | 10018 |
| RPL12 | 9972 |
| LCK | 9872 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TUBB8 | 10619.0 |
| GNGT2 | 10606.0 |
| TUBB4B | 10587.0 |
| IFNA1 | 10538.0 |
| CD8B | 10454.0 |
| RPL39L | 10429.0 |
| IFNA8 | 10386.0 |
| RPLP1 | 10383.0 |
| CTSG | 10382.0 |
| UBB | 10269.0 |
| IFNA16 | 10244.0 |
| RPL19 | 10237.0 |
| H3C12 | 10132.0 |
| RPL27A | 10126.0 |
| NOXO1 | 10107.0 |
| RPL38 | 10097.0 |
| RPS12 | 10065.0 |
| RPL27 | 10018.0 |
| RPL12 | 9972.0 |
| LCK | 9872.0 |
| ATP1B2 | 9863.0 |
| RPL5 | 9847.0 |
| IFNA7 | 9843.0 |
| H2AC17 | 9828.0 |
| RPL10A | 9823.0 |
| HBEGF | 9808.0 |
| DAD1 | 9793.0 |
| CD79A | 9765.0 |
| TBP | 9764.0 |
| GTF2H3 | 9734.0 |
| TOMM70 | 9733.0 |
| SNRPF | 9718.0 |
| GNG11 | 9653.0 |
| PYCARD | 9642.0 |
| RPSA | 9598.0 |
| AP1M2 | 9593.0 |
| VAMP1 | 9560.0 |
| CD3G | 9519.0 |
| EEF1A1 | 9508.0 |
| SAP30L | 9506.0 |
| RPL35A | 9504.0 |
| CALR | 9479.0 |
| H2BC14 | 9436.0 |
| CD28 | 9432.0 |
| H4C8 | 9408.0 |
| TUBA4A | 9371.0 |
| TPR | 9369.0 |
| RPL13 | 9355.0 |
| NUP35 | 9338.0 |
| SUGT1 | 9329.0 |
| CRB3 | 9321.0 |
| H2AC14 | 9305.0 |
| SAP30 | 9292.0 |
| PSMB3 | 9282.0 |
| TUBB3 | 9276.0 |
| DDX20 | 9274.0 |
| RPL11 | 9263.0 |
| GEMIN2 | 9249.0 |
| H2BC17 | 9247.0 |
| NUP107 | 9241.0 |
| TAF13 | 9240.0 |
| DPEP2 | 9237.0 |
| GNG5 | 9165.0 |
| RCAN3 | 9132.0 |
| NFKBIA | 9116.0 |
| H3C3 | 9111.0 |
| PSMA6 | 9088.0 |
| FXYD7 | 9068.0 |
| IFIH1 | 8998.0 |
| ACTB | 8973.0 |
| GRB2 | 8950.0 |
| RPL34 | 8949.0 |
| PSMA7 | 8947.0 |
| STAM2 | 8933.0 |
| SLC25A4 | 8905.0 |
| ATP1B1 | 8810.0 |
| GNG8 | 8809.0 |
| GTF2E1 | 8805.0 |
| POLR2L | 8803.0 |
| HLA-G | 8760.0 |
| WASF1 | 8742.0 |
| PSME2 | 8738.0 |
| NUP43 | 8731.0 |
| ITGA4 | 8730.0 |
| TAF9 | 8727.0 |
| PSMC5 | 8695.0 |
| UBC | 8680.0 |
| PSMA1 | 8676.0 |
| CXCR4 | 8652.0 |
| H2BC5 | 8646.0 |
| HLA-F | 8642.0 |
| TUBB2B | 8597.0 |
| IL6R | 8593.0 |
| MGAT2 | 8546.5 |
| RPL36AL | 8546.5 |
| CD247 | 8533.0 |
| MAPK14 | 8531.0 |
| POLR2D | 8521.0 |
| TUFM | 8502.0 |
| B2M | 8487.0 |
| POLR2C | 8482.0 |
| IFNAR1 | 8474.0 |
| TAF15 | 8468.0 |
| CANX | 8449.0 |
| RPL18A | 8433.0 |
| RPS18 | 8418.0 |
| RPL7 | 8407.0 |
| YWHAH | 8406.0 |
| IRF3 | 8402.0 |
| SRPK1 | 8389.0 |
| H4C4 | 8378.0 |
| PSMD12 | 8377.0 |
| RPS14 | 8367.0 |
| RIPK3 | 8285.0 |
| PCBP2 | 8264.0 |
| CAV1 | 8242.0 |
| NUP153 | 8165.0 |
| PSMB1 | 8157.0 |
| SNRPD2 | 8144.0 |
| ATP1B3 | 8136.0 |
| RPL37 | 8126.0 |
| SIKE1 | 8122.0 |
| RNMT | 8078.0 |
| H2AC16 | 8075.0 |
| HSPA1A | 8066.0 |
| PPIH | 8060.0 |
| JUN | 8056.0 |
| RPS28 | 8053.0 |
| TUBA4B | 8052.0 |
| BANF1 | 8044.0 |
| PSMC4 | 8042.0 |
| H2AC11 | 8024.0 |
| GPS2 | 8022.0 |
| FEN1 | 7987.0 |
| TUBB6 | 7982.0 |
| H2BC4 | 7968.0 |
| RPL7A | 7958.0 |
| GNG10 | 7941.0 |
| UBE2V1 | 7929.0 |
| SP1 | 7917.0 |
| IL18 | 7912.0 |
| TAF6 | 7909.0 |
| PRKAR1A | 7901.0 |
| SIGMAR1 | 7884.0 |
| PPIG | 7844.0 |
| ST6GAL1 | 7829.0 |
| RPL23 | 7819.0 |
| ACTR3 | 7818.0 |
| C3AR1 | 7752.0 |
| PDCD6IP | 7746.0 |
| IFNA21 | 7738.0 |
| WNT5A | 7724.0 |
| H2AC15 | 7723.0 |
| SYK | 7712.0 |
| UBAP1 | 7699.0 |
| GOLGA7 | 7681.0 |
| SNRPD3 | 7673.0 |
| POLR2I | 7672.0 |
| NUP155 | 7642.0 |
| ISCU | 7618.0 |
| RPL6 | 7585.0 |
| CNBP | 7582.0 |
| XPO1 | 7555.0 |
| CTSL | 7520.0 |
| ELOC | 7494.0 |
| RPL28 | 7492.0 |
| SFPQ | 7467.0 |
| PRKCSH | 7461.0 |
| RPLP0 | 7456.0 |
| MGAT1 | 7426.0 |
| RPS10 | 7422.0 |
| CHMP2B | 7377.0 |
| ZCRB1 | 7346.0 |
| GATAD2B | 7334.0 |
| POLR2H | 7324.0 |
| H2AC18 | 7261.5 |
| H2AC19 | 7261.5 |
| S1PR1 | 7255.0 |
| RPS9 | 7239.0 |
| PSMB9 | 7201.0 |
| LYN | 7167.0 |
| GSK3A | 7107.0 |
| RAC1 | 7075.0 |
| RPL3 | 7066.0 |
| XRCC6 | 7055.0 |
| HLA-E | 7027.0 |
| RAB7A | 7007.0 |
| H2AC6 | 7006.0 |
| HNRNPA1 | 6967.0 |
| MEFV | 6927.0 |
| UBA52 | 6901.0 |
| TUBA8 | 6874.0 |
| GEMIN6 | 6871.0 |
| IL1A | 6845.0 |
| RPL4 | 6839.0 |
| AHCYL1 | 6825.0 |
| ANO5 | 6816.0 |
| RPL23A | 6780.0 |
| H2BC15 | 6756.0 |
| H4C3 | 6755.0 |
| RPS13 | 6745.0 |
| RPL32 | 6717.0 |
| H2BC9 | 6696.5 |
| H3C7 | 6696.5 |
| PTPN11 | 6694.0 |
| MVB12A | 6670.0 |
| SMAD4 | 6630.0 |
| IFNA13 | 6601.0 |
| ARPC1A | 6593.0 |
| SH3GL2 | 6583.0 |
| H2AC4 | 6574.0 |
| ADCY8 | 6540.0 |
| TXNIP | 6528.0 |
| ATP1A1 | 6490.0 |
| HSP90AB1 | 6482.0 |
| H4C5 | 6455.0 |
| PRKAR2A | 6454.0 |
| HAVCR1 | 6441.0 |
| ST6GALNAC2 | 6434.0 |
| FKBP1A | 6399.0 |
| ENO1 | 6322.0 |
| RPS21 | 6312.0 |
| TCEA1 | 6293.0 |
| G3BP1 | 6289.0 |
| PSMB7 | 6283.0 |
| DYNC1I2 | 6238.0 |
| IFNAR2 | 6225.0 |
| RPS27A | 6223.0 |
| PSMB10 | 6211.0 |
| RPS23 | 6171.0 |
| RPS2 | 6145.0 |
| CHMP2A | 6123.0 |
| ATG14 | 6107.0 |
| RPL8 | 6083.0 |
| YWHAZ | 6039.0 |
| POLR2E | 6038.0 |
| PSMB8 | 6003.0 |
| KPNB1 | 5984.0 |
| SUPT16H | 5947.0 |
| PSMD13 | 5916.0 |
| DAXX | 5912.0 |
| RBBP4 | 5906.0 |
| RPS3A | 5876.0 |
| FCGR3A | 5856.0 |
| SEC24B | 5834.0 |
| TAF7 | 5814.0 |
| MGAT5 | 5739.0 |
| NUP54 | 5663.0 |
| RPS27L | 5650.0 |
| EED | 5630.0 |
| CCNH | 5625.0 |
| GNB2 | 5561.0 |
| RPS16 | 5552.0 |
| TAF11 | 5531.0 |
| NUP50 | 5527.0 |
| ARPC1B | 5488.0 |
| ARPC5 | 5476.0 |
| KPNA3 | 5474.0 |
| ZDHHC5 | 5429.0 |
| NR3C1 | 5426.0 |
| PSMC6 | 5420.0 |
| RPL15 | 5410.0 |
| SEC24A | 5403.0 |
| SKP1 | 5377.0 |
| FAU | 5376.0 |
| POLR2K | 5369.0 |
| HDAC3 | 5330.0 |
| MOGS | 5312.0 |
| IRAK2 | 5303.0 |
| VAV1 | 5269.0 |
| GNAI3 | 5238.0 |
| GNAI2 | 5149.0 |
| SUPT5H | 5131.0 |
| H2BC3 | 5022.0 |
| RNF135 | 5018.0 |
| SV2C | 4986.0 |
| TAF5 | 4981.0 |
| SYT1 | 4980.0 |
| PSMA4 | 4963.0 |
| PSMD7 | 4932.0 |
| TAF12 | 4927.0 |
| SDC2 | 4916.0 |
| ZDHHC8 | 4890.0 |
| TLR9 | 4858.0 |
| H4C9 | 4853.0 |
| RPL18 | 4825.0 |
| NFE2L2 | 4811.0 |
| PPIB | 4755.0 |
| TUBB | 4729.0 |
| SERPINE1 | 4724.0 |
| ENTPD5 | 4718.0 |
| FXYD1 | 4715.0 |
| H4C16 | 4688.0 |
| AP2S1 | 4656.0 |
| HMGA1 | 4651.0 |
| CYSLTR2 | 4649.0 |
| BLNK | 4620.0 |
| VPS25 | 4595.0 |
| NCBP1 | 4593.0 |
| RPL26 | 4557.0 |
| H2BC6 | 4552.0 |
| WASF2 | 4545.0 |
| GANAB | 4538.0 |
| ARPC3 | 4525.0 |
| ITCH | 4511.0 |
| PPIA | 4505.0 |
| RPL17 | 4473.0 |
| RPS11 | 4468.0 |
| ANO2 | 4431.0 |
| PARP1 | 4427.0 |
| AP1G1 | 4407.0 |
| RPL21 | 4396.0 |
| POM121 | 4393.0 |
| CLTA | 4366.0 |
| FGR | 4311.0 |
| ARID4A | 4305.0 |
| ELOB | 4304.0 |
| H4C2 | 4300.0 |
| TBK1 | 4287.0 |
| IL1B | 4187.0 |
| GNG2 | 4186.0 |
| RPS20 | 4174.0 |
| RPS15A | 4169.0 |
| VPS33B | 4152.0 |
| ENTPD1 | 4119.0 |
| RPS8 | 4117.0 |
| PSMA3 | 4116.0 |
| NMI | 4102.0 |
| ABI2 | 4100.0 |
| GTF2E2 | 4090.0 |
| H4C6 | 4018.0 |
| RAB5A | 4009.0 |
| GSK3B | 4006.0 |
| LIG4 | 3996.0 |
| GNAI1 | 3982.0 |
| PALS1 | 3977.0 |
| TLR1 | 3974.0 |
| CBLL1 | 3973.0 |
| RPL30 | 3957.0 |
| IL6 | 3948.0 |
| SUZ12 | 3929.0 |
| EPS15 | 3912.0 |
| RBX1 | 3880.0 |
| CHMP7 | 3806.0 |
| PTPN6 | 3805.0 |
| POM121C | 3776.0 |
| VPS45 | 3715.0 |
| RPL26L1 | 3710.0 |
| EDEM2 | 3686.0 |
| MGAT4C | 3684.0 |
| RAN | 3664.0 |
| H2BC12 | 3661.0 |
| REST | 3638.0 |
| CYBA | 3616.0 |
| CHMP4C | 3587.0 |
| WASL | 3572.0 |
| RPS19 | 3558.0 |
| GTF2H4 | 3554.0 |
| KDM1A | 3552.0 |
| DYNC1LI1 | 3543.0 |
| SNF8 | 3513.0 |
| NPM1 | 3501.0 |
| UBE2N | 3457.0 |
| NUP133 | 3422.0 |
| RPS5 | 3408.0 |
| WIPF1 | 3403.0 |
| RPS24 | 3357.0 |
| JAK1 | 3343.0 |
| RPS7 | 3333.0 |
| PSMB2 | 3326.0 |
| ACTG1 | 3324.0 |
| SAR1B | 3291.0 |
| H2AC20 | 3275.0 |
| ZDHHC2 | 3248.0 |
| TUBA1B | 3208.0 |
| NUP205 | 3185.0 |
| CCR5 | 3184.0 |
| LTF | 3181.0 |
| CCNK | 3169.0 |
| SV2B | 3161.0 |
| CORO1A | 3137.0 |
| VPS37A | 3124.0 |
| H2AC21 | 3071.0 |
| RPL37A | 3063.0 |
| PARP8 | 3054.0 |
| PSMB4 | 3049.0 |
| IMPDH2 | 3042.0 |
| HLA-C | 3024.0 |
| TBL1XR1 | 3008.0 |
| PSMC1 | 2987.0 |
| H3C2 | 2976.0 |
| GTF2H5 | 2954.0 |
| RPN1 | 2950.0 |
| PRKAR2B | 2917.0 |
| MAP2K3 | 2877.0 |
| RPL22 | 2864.0 |
| PARP10 | 2843.0 |
| NOD1 | 2826.0 |
| AP2B1 | 2824.0 |
| RPS29 | 2812.0 |
| CLTC | 2808.0 |
| P2RX7 | 2750.0 |
| VPS36 | 2735.0 |
| ANO8 | 2705.0 |
| RPL35 | 2694.0 |
| YWHAG | 2674.0 |
| BRK1 | 2660.0 |
| CSNK1A1 | 2642.0 |
| ROCK1 | 2609.0 |
| RPS26 | 2583.0 |
| SSRP1 | 2557.0 |
| TXN | 2519.0 |
| GNG12 | 2515.0 |
| CCNT2 | 2512.0 |
| NCKAP1L | 2509.0 |
| H2BC11 | 2506.0 |
| HDAC2 | 2488.0 |
| MNAT1 | 2449.0 |
| GTF2H1 | 2440.0 |
| YWHAE | 2415.0 |
| NDC1 | 2410.0 |
| PSMA8 | 2379.0 |
| NLRP12 | 2367.0 |
| SDC3 | 2347.0 |
| ANO4 | 2338.0 |
| GNG13 | 2324.0 |
| VPS37C | 2266.0 |
| ELOA2 | 2265.0 |
| MYO5A | 2255.0 |
| CHMP4B | 2240.0 |
| RPS27 | 2232.0 |
| VAMP2 | 2227.0 |
| ELOA | 2222.0 |
| GUCY2C | 2198.0 |
| SEC23A | 2169.0 |
| PSMD1 | 2144.0 |
| POLR2G | 2138.0 |
| MAPK1 | 2130.0 |
| PSME4 | 2128.0 |
| AP1S1 | 2112.0 |
| PSMB5 | 2078.0 |
| ANTXR2 | 2064.0 |
| RPS25 | 2059.0 |
| ARPC2 | 2058.0 |
| HSP90AA1 | 2049.0 |
| VPS37D | 2046.0 |
| CUL5 | 1970.0 |
| APP | 1968.0 |
| STX1A | 1966.0 |
| IMPDH1 | 1955.0 |
| ARPC4 | 1905.0 |
| DYNC1I1 | 1903.0 |
| IFNGR1 | 1867.0 |
| PRKACB | 1818.0 |
| GSDMD | 1798.0 |
| RPL22L1 | 1785.0 |
| PSMC3 | 1749.0 |
| H2BC21 | 1717.0 |
| ARID4B | 1666.0 |
| DDX5 | 1661.0 |
| SEM1 | 1657.0 |
| PSMC2 | 1653.0 |
| CREB1 | 1614.0 |
| HCK | 1611.0 |
| SEC24C | 1576.0 |
| NCBP2 | 1556.0 |
| CCNT1 | 1512.0 |
| HLA-B | 1510.0 |
| PSMD4 | 1403.0 |
| VPS4B | 1386.0 |
| NUP88 | 1277.0 |
| CBL | 1270.0 |
| CDH1 | 1268.0 |
| MYO10 | 1266.0 |
| RPS6 | 1237.0 |
| RAE1 | 1215.0 |
| RANBP2 | 1191.0 |
| KPNA7 | 1102.0 |
| ANO3 | 1101.0 |
| SNRPE | 1062.0 |
| MET | 1042.0 |
| TRIM28 | 1038.0 |
| GPC5 | 1032.0 |
| CBX1 | 956.0 |
| GJA1 | 952.0 |
| CDK7 | 909.0 |
| RPL24 | 901.0 |
| KPNA4 | 895.0 |
| NT5E | 862.0 |
| MVB12B | 860.0 |
| GGT5 | 856.0 |
| BRMS1 | 792.0 |
| ABI1 | 756.0 |
| MYH9 | 748.0 |
| MAN2A1 | 743.0 |
| TAF3 | 739.0 |
| BCL2L1 | 707.0 |
| PSMA5 | 665.0 |
| BST2 | 636.0 |
| SUPT4H1 | 630.0 |
| NUP160 | 618.0 |
| H3C11 | 608.0 |
| ABL1 | 607.0 |
| GATAD2A | 595.0 |
| XRCC4 | 580.0 |
| RIPK2 | 566.0 |
| NCOR1 | 549.0 |
| ITPR2 | 528.0 |
| VAV3 | 499.0 |
| PSMA2 | 467.0 |
| PLCG2 | 414.0 |
| ANTXR1 | 411.0 |
| EZH2 | 400.0 |
| NUP98 | 368.0 |
| SNAP25 | 361.0 |
| VPS11 | 357.0 |
| GPC6 | 308.0 |
| TXNRD1 | 306.0 |
| GTF2B | 289.0 |
| PSMD3 | 274.0 |
| WIPF2 | 265.0 |
| FKBP4 | 255.0 |
| VPS18 | 242.0 |
| IFNGR2 | 152.0 |
| TRIM4 | 149.0 |
| RPLP2 | 141.0 |
| ADAM17 | 68.0 |
| VPS41 | 49.0 |
| MAP2K1 | 46.0 |
| NFKB1 | 12.0 |
| NFKB2 | -23.0 |
| ADCY9 | -47.0 |
| H4C1 | -64.0 |
| FUT8 | -69.0 |
| GNB5 | -74.0 |
| NCKAP1 | -89.0 |
| GEMIN7 | -95.0 |
| HMG20B | -104.0 |
| PARP9 | -113.0 |
| NELFB | -143.0 |
| RB1 | -156.0 |
| H3C6 | -174.0 |
| MAP3K7 | -189.0 |
| PSMD14 | -192.0 |
| RCOR1 | -196.0 |
| BTRC | -218.0 |
| H2AC13 | -254.0 |
| MGAT4A | -297.0 |
| KPNA5 | -359.0 |
| CD9 | -376.0 |
| RPL9 | -399.0 |
| PTGES3 | -434.0 |
| PIK3C3 | -472.0 |
| HLA-A | -480.0 |
| STAM | -489.0 |
| MTA2 | -511.0 |
| TUBB4A | -521.0 |
| NMT2 | -564.0 |
| PSME3 | -576.0 |
| H2BC10 | -630.0 |
| RPL29 | -634.0 |
| HNRNPK | -680.0 |
| SEH1L | -682.0 |
| ST6GALNAC4 | -707.0 |
| GNB4 | -731.0 |
| PLCG1 | -770.0 |
| ADCY7 | -771.0 |
| MYH2 | -776.0 |
| BECN1 | -781.0 |
| PML | -830.0 |
| STAT1 | -837.0 |
| PSME1 | -840.0 |
| RPL36 | -891.0 |
| RPS3 | -935.0 |
| TSG101 | -940.0 |
| KPNA2 | -967.0 |
| H3C8 | -1062.0 |
| PSMD6 | -1076.0 |
| YWHAQ | -1078.0 |
| PSMD11 | -1095.0 |
| EP300 | -1121.0 |
| PIK3R4 | -1122.0 |
| NUP42 | -1128.0 |
| H4C13 | -1134.0 |
| ZDHHC3 | -1140.0 |
| TAF1L | -1149.0 |
| TUBA1A | -1153.0 |
| FYN | -1167.0 |
| PSTPIP1 | -1195.0 |
| VPS33A | -1203.0 |
| TRIM27 | -1205.0 |
| NCK1 | -1237.0 |
| FXYD6 | -1297.0 |
| SYT2 | -1308.0 |
| RPN2 | -1352.0 |
| DYNLL1 | -1359.0 |
| XRCC5 | -1378.0 |
| ADCY6 | -1396.0 |
| ITPR1 | -1419.0 |
| TJP1 | -1476.0 |
| SMN1 | -1491.5 |
| SMN2 | -1491.5 |
| ERCC3 | -1589.0 |
| PSMD5 | -1600.0 |
| VHL | -1609.0 |
| MAP1LC3B | -1634.0 |
| STT3A | -1650.0 |
| NELFE | -1661.0 |
| VTA1 | -1703.0 |
| YWHAB | -1708.0 |
| PSMD8 | -1715.0 |
| MAPK8 | -1743.0 |
| NUP37 | -1790.0 |
| GTF2F1 | -1794.0 |
| SH3GL3 | -1797.0 |
| PSMD9 | -1897.0 |
| H4C12 | -1933.0 |
| UVRAG | -1993.0 |
| GTF2A1 | -2018.0 |
| H3C1 | -2029.0 |
| SH3GL1 | -2061.0 |
| CEBPD | -2132.0 |
| VEGFA | -2133.0 |
| G3BP2 | -2166.0 |
| TAB1 | -2208.0 |
| PLK2 | -2238.0 |
| GTF2A2 | -2258.0 |
| CASP1 | -2295.0 |
| ADCY2 | -2344.0 |
| SEC13 | -2354.0 |
| ATP6V1H | -2355.0 |
| GTF2F2 | -2395.0 |
| DUSP16 | -2413.0 |
| STAT2 | -2438.0 |
| ACTR2 | -2440.0 |
| TMPRSS2 | -2508.0 |
| MAVS | -2509.0 |
| TUSC3 | -2514.0 |
| RIGI | -2535.0 |
| DVL2 | -2561.0 |
| TRAF6 | -2592.0 |
| TGFB1 | -2596.0 |
| GEMIN4 | -2600.0 |
| CHD3 | -2612.0 |
| RPL41 | -2639.0 |
| SAP18 | -2669.0 |
| PARP4 | -2718.0 |
| PATJ | -2732.0 |
| TUBB2A | -2758.0 |
| RPL13A | -2765.5 |
| RPS15 | -2768.0 |
| EIF2AK2 | -2770.0 |
| AP2A1 | -2782.0 |
| TKFC | -2784.0 |
| CTNNB1 | -2828.0 |
| ST6GALNAC3 | -2901.0 |
| C3 | -2921.0 |
| IRF7 | -2924.0 |
| ANO9 | -2928.0 |
| TAF10 | -2930.0 |
| ELMO1 | -3038.0 |
| PARP16 | -3123.0 |
| ISG15 | -3143.0 |
| PACS1 | -3271.0 |
| CYFIP2 | -3298.0 |
| KPNA1 | -3299.0 |
| COMT | -3318.0 |
| ANO6 | -3379.0 |
| TRIM25 | -3391.0 |
| NLRP3 | -3412.0 |
| H2BC13 | -3416.0 |
| ARF1 | -3428.0 |
| ZDHHC20 | -3465.0 |
| RPL31 | -3475.0 |
| CALM1 | -3487.0 |
| RCC1 | -3494.0 |
| CHMP3 | -3516.0 |
| SUMO1 | -3519.0 |
| ANO10 | -3530.0 |
| POLR2B | -3675.0 |
| MASP1 | -3702.0 |
| STING1 | -3751.0 |
| PARP14 | -3766.0 |
| H2AC12 | -3780.0 |
| AP1S3 | -3807.0 |
| WASF3 | -3868.0 |
| PTK2 | -3878.0 |
| SNRPG | -3880.0 |
| SUDS3 | -3897.0 |
| IL10 | -3899.0 |
| NOXA1 | -3919.0 |
| ITGB1 | -3975.0 |
| GNGT1 | -3999.0 |
| NRP1 | -4010.0 |
| CD163 | -4011.0 |
| PRMT1 | -4014.0 |
| GNG4 | -4057.0 |
| DOCK1 | -4069.0 |
| ATP1A3 | -4115.0 |
| CRBN | -4176.0 |
| PSMF1 | -4178.0 |
| H3C4 | -4187.0 |
| H2AC7 | -4211.0 |
| H2BC7 | -4211.0 |
| MAN1B1 | -4257.0 |
| H2AC8 | -4264.0 |
| VPS39 | -4378.0 |
| SV2A | -4404.0 |
| GRSF1 | -4457.0 |
| PABPN1 | -4462.0 |
| RNGTT | -4464.0 |
| NUP214 | -4467.0 |
| JAK2 | -4578.0 |
| GPC2 | -4616.0 |
| YES1 | -4728.0 |
| IFNB1 | -4761.0 |
| TUBA1C | -4828.0 |
| TAF4B | -4863.0 |
| IL1R1 | -4872.0 |
| EEF2 | -4923.0 |
| ST3GAL1 | -4952.0 |
| GNB1 | -4968.0 |
| CRK | -5019.0 |
| VCP | -5021.0 |
| H2BC8 | -5026.0 |
| CDK9 | -5042.0 |
| SDC1 | -5052.0 |
| AKT3 | -5060.0 |
| PAK2 | -5084.0 |
| MAP2K7 | -5085.0 |
| H2AC25 | -5103.0 |
| IL17RC | -5117.0 |
| TRAF3 | -5135.0 |
| NMT1 | -5155.0 |
| NUP93 | -5201.0 |
| IFNA2 | -5203.0 |
| JAK3 | -5232.0 |
| POLR2F | -5251.0 |
| TAB2 | -5288.0 |
| HDAC1 | -5289.0 |
| PSMB6 | -5356.0 |
| SOS1 | -5362.0 |
| ST3GAL3 | -5377.0 |
| SEC24D | -5386.0 |
| DOCK2 | -5400.0 |
| DYNC1LI2 | -5447.0 |
| ST3GAL2 | -5472.0 |
| MAP2K6 | -5479.0 |
| IKBKE | -5538.0 |
| AP1B1 | -5548.0 |
| RUNX1 | -5564.0 |
| MTA3 | -5592.0 |
| GEMIN5 | -5594.0 |
| WIPF3 | -5620.0 |
| RHBDF2 | -5625.0 |
| CDC42 | -5666.0 |
| FZD7 | -5672.0 |
| RPL14 | -5770.0 |
| SRPK2 | -5804.0 |
| PDPK1 | -5927.0 |
| VPS28 | -5958.0 |
| PHF21A | -5981.0 |
| RELA | -6000.0 |
| VPS37B | -6014.0 |
| CD79B | -6123.0 |
| NUP62 | -6129.0 |
| PSMD2 | -6144.0 |
| PRKACA | -6164.0 |
| IFNA6 | -6186.0 |
| MYO9B | -6214.0 |
| PARP6 | -6281.0 |
| ADORA2B | -6289.0 |
| GNG7 | -6321.0 |
| CHD4 | -6325.0 |
| IKBKB | -6328.0 |
| MBD3 | -6330.0 |
| CUL3 | -6363.0 |
| IL17A | -6386.0 |
| SNRPB | -6416.0 |
| IFNA5 | -6425.0 |
| DPEP1 | -6492.0 |
| LARP1 | -6573.0 |
| ADCY1 | -6579.0 |
| CHUK | -6586.0 |
| TAF2 | -6609.0 |
| DYNLL2 | -6691.0 |
| SNRPD1 | -6773.0 |
| NOS2 | -6829.0 |
| CHMP4A | -6869.0 |
| GNAT3 | -6883.0 |
| NCKIPSD | -6914.0 |
| ADCY4 | -6976.0 |
| CHMP1A | -6982.0 |
| SDC4 | -6994.0 |
| IPO5 | -7010.0 |
| FNTB | -7073.0 |
| CPSF4 | -7119.0 |
| NUP188 | -7120.0 |
| KEAP1 | -7145.0 |
| NEDD4L | -7230.0 |
| IL17RA | -7287.0 |
| ADCY5 | -7298.0 |
| CHMP5 | -7316.0 |
| ELMO2 | -7317.0 |
| ELL | -7332.0 |
| PSIP1 | -7346.0 |
| EGFR | -7359.0 |
| DDOST | -7370.0 |
| MAP2K4 | -7373.0 |
| H2BC26 | -7437.0 |
| SMAD3 | -7487.0 |
| TUBAL3 | -7519.0 |
| P2RX4 | -7525.0 |
| DPEP3 | -7553.0 |
| FXYD2 | -7602.0 |
| AP1M1 | -7628.0 |
| ANO1 | -7633.0 |
| H2AC1 | -7658.0 |
| MBL2 | -7683.0 |
| NELFA | -7695.0 |
| FURIN | -7705.0 |
| CHMP6 | -7771.0 |
| STX1B | -7781.0 |
| UBE2I | -7784.0 |
| NUP58 | -7794.0 |
| RIPK1 | -7795.0 |
| MGAT4B | -7797.0 |
| TLR2 | -7832.0 |
| CTNND1 | -7848.0 |
| RANGAP1 | -7942.0 |
| VPS4A | -7952.0 |
| MYO1C | -7966.0 |
| PKLR | -7988.0 |
| TUBA3C | -7998.0 |
| FNTA | -8045.0 |
| AP2M1 | -8095.0 |
| H2BC1 | -8099.0 |
| ERCC2 | -8106.0 |
| ANO7 | -8134.0 |
| TUBB1 | -8166.0 |
| POLR2A | -8208.0 |
| NUP85 | -8221.0 |
| NELFCD | -8227.0 |
| AAAS | -8286.0 |
| AP2A2 | -8288.0 |
| CREBBP | -8338.0 |
| ZDHHC11 | -8417.0 |
| VAV2 | -8501.0 |
| NUP210 | -8505.0 |
| HSPG2 | -8522.0 |
| H3C10 | -8558.0 |
| HGS | -8598.0 |
| TUBA3E | -8617.0 |
| ROCK2 | -8646.0 |
| ITPR3 | -8659.0 |
| SFN | -8815.0 |
| GPC1 | -8827.0 |
| PRKACG | -8839.0 |
| GNAS | -8843.0 |
| BAIAP2 | -8844.0 |
| ST3GAL4 | -8858.0 |
| IFNA14 | -8933.0 |
| HMOX1 | -8934.0 |
| NCOR2 | -9014.0 |
| DVL1 | -9072.0 |
| LIG1 | -9074.0 |
| TYK2 | -9118.0 |
| SFTPD | -9151.0 |
| H4C11 | -9168.0 |
| ADCY3 | -9298.0 |
| RNF213 | -9352.0 |
| SRC | -9360.0 |
| GNG3 | -9390.0 |
| AGRN | -9394.0 |
| CYFIP1 | -9437.0 |
| CD4 | -9440.0 |
| RANBP1 | -9448.0 |
| PRKAR1B | -9452.0 |
| GALNT1 | -9461.0 |
| DNAJC3 | -9484.0 |
| DYNC1H1 | -9522.0 |
| DVL3 | -9524.0 |
| ATP1A4 | -9544.0 |
| AKT2 | -9562.0 |
| FCGR2A | -9639.0 |
| IL17F | -9692.0 |
| ATP1A2 | -9744.0 |
| MAPK3 | -9797.0 |
| GGT1 | -9801.0 |
| NOD2 | -9873.0 |
| ZBP1 | -9904.0 |
| MASP2 | -9907.0 |
| CTDP1 | -9960.0 |
| FXYD3 | -10030.0 |
| GNAZ | -10032.0 |
| AKT1 | -10034.0 |
| VPS16 | -10129.0 |
| MAP2K2 | -10136.0 |
| TAF4 | -10304.0 |
| PDCD1 | -10536.0 |
| BRD4 | -10633.0 |
| PSMB11 | -10657.0 |
| GNB3 | -10659.0 |
| TUBA3D | -10666.0 |
| FXYD4 | -10790.0 |
| MTA1 | -10809.0 |
| RPL3L | -10862.0 |
| POLR2J | -10901.0 |
| APOBEC3G | -10980.0 |
| RPL10L | -10981.0 |
REACTOME_SELENOAMINO_ACID_METABOLISM
| 484 | |
|---|---|
| set | REACTOME_SELENOAMINO_ACID_METABOLISM |
| setSize | 108 |
| pANOVA | 1.46e-10 |
| s.dist | 0.357 |
| p.adjustANOVA | 1.59e-08 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL39L | 10429.0 |
| RPLP1 | 10383.0 |
| RPL19 | 10237.0 |
| RPL27A | 10126.0 |
| RPL38 | 10097.0 |
| RPS12 | 10065.0 |
| RPL27 | 10018.0 |
| RPL12 | 9972.0 |
| RPL5 | 9847.0 |
| RPL10A | 9823.0 |
| RPSA | 9598.0 |
| RPL35A | 9504.0 |
| RPL13 | 9355.0 |
| RPL11 | 9263.0 |
| RPL34 | 8949.0 |
| RPL36AL | 8546.5 |
| RPL18A | 8433.0 |
| RPS18 | 8418.0 |
| RPL7 | 8407.0 |
| RPS14 | 8367.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL39L | 10429.0 |
| RPLP1 | 10383.0 |
| RPL19 | 10237.0 |
| RPL27A | 10126.0 |
| RPL38 | 10097.0 |
| RPS12 | 10065.0 |
| RPL27 | 10018.0 |
| RPL12 | 9972.0 |
| RPL5 | 9847.0 |
| RPL10A | 9823.0 |
| RPSA | 9598.0 |
| RPL35A | 9504.0 |
| RPL13 | 9355.0 |
| RPL11 | 9263.0 |
| RPL34 | 8949.0 |
| RPL36AL | 8546.5 |
| RPL18A | 8433.0 |
| RPS18 | 8418.0 |
| RPL7 | 8407.0 |
| RPS14 | 8367.0 |
| EEF1E1 | 8291.0 |
| RPL37 | 8126.0 |
| RPS28 | 8053.0 |
| RPL7A | 7958.0 |
| RPL23 | 7819.0 |
| NNMT | 7807.0 |
| LARS1 | 7756.0 |
| GNMT | 7609.0 |
| RPL6 | 7585.0 |
| RPL28 | 7492.0 |
| RPLP0 | 7456.0 |
| RPS10 | 7422.0 |
| RPS9 | 7239.0 |
| SEPHS2 | 7166.0 |
| RPL3 | 7066.0 |
| UBA52 | 6901.0 |
| RPL4 | 6839.0 |
| RPL23A | 6780.0 |
| RPS13 | 6745.0 |
| RPL32 | 6717.0 |
| RPS21 | 6312.0 |
| RPS27A | 6223.0 |
| AHCY | 6208.0 |
| RPS23 | 6171.0 |
| RPS2 | 6145.0 |
| RPL8 | 6083.0 |
| RPS3A | 5876.0 |
| AIMP1 | 5852.0 |
| RPS27L | 5650.0 |
| RPS16 | 5552.0 |
| RPL15 | 5410.0 |
| FAU | 5376.0 |
| CTH | 5261.0 |
| RPL18 | 4825.0 |
| RPL26 | 4557.0 |
| DARS1 | 4553.0 |
| RPL17 | 4473.0 |
| RPS11 | 4468.0 |
| RPL21 | 4396.0 |
| RPS20 | 4174.0 |
| RPS15A | 4169.0 |
| RPS8 | 4117.0 |
| KARS1 | 4073.0 |
| RPL30 | 3957.0 |
| RPL26L1 | 3710.0 |
| RPS19 | 3558.0 |
| RPS5 | 3408.0 |
| RPS24 | 3357.0 |
| RPS7 | 3333.0 |
| HNMT | 3080.0 |
| RPL37A | 3063.0 |
| RPL22 | 2864.0 |
| RPS29 | 2812.0 |
| RPL35 | 2694.0 |
| RPS26 | 2583.0 |
| RPS27 | 2232.0 |
| RPS25 | 2059.0 |
| RARS1 | 1805.0 |
| RPL22L1 | 1785.0 |
| RPS6 | 1237.0 |
| RPL24 | 901.0 |
| TXNRD1 | 306.0 |
| RPLP2 | 141.0 |
| RPL9 | -399.0 |
| RPL29 | -634.0 |
| RPL36 | -891.0 |
| RPS3 | -935.0 |
| PSTK | -1685.0 |
| PAPSS2 | -1765.0 |
| SECISBP2 | -2406.0 |
| RPL41 | -2639.0 |
| RPL13A | -2765.5 |
| RPS15 | -2768.0 |
| PAPSS1 | -3129.0 |
| RPL31 | -3475.0 |
| GSR | -4001.0 |
| EPRS1 | -4013.0 |
| SEPSECS | -4396.0 |
| AIMP2 | -4699.0 |
| MAT1A | -5153.0 |
| RPL14 | -5770.0 |
| SCLY | -6035.0 |
| IARS1 | -6986.0 |
| MARS1 | -8262.0 |
| EEFSEC | -9450.0 |
| INMT | -10126.0 |
| RPL3L | -10862.0 |
| RPL10L | -10981.0 |
REACTOME_CELLULAR_RESPONSE_TO_STARVATION
| 1582 | |
|---|---|
| set | REACTOME_CELLULAR_RESPONSE_TO_STARVATION |
| setSize | 147 |
| pANOVA | 3.27e-10 |
| s.dist | 0.3 |
| p.adjustANOVA | 3.35e-08 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| ATP6V1G1 | 10435 |
| RPL39L | 10429 |
| RPLP1 | 10383 |
| RPL19 | 10237 |
| RPL27A | 10126 |
| RPL38 | 10097 |
| RPS12 | 10065 |
| RPL27 | 10018 |
| RPL12 | 9972 |
| RPL5 | 9847 |
| RPL10A | 9823 |
| RPSA | 9598 |
| RPL35A | 9504 |
| RPL13 | 9355 |
| RPL11 | 9263 |
| LAMTOR2 | 9029 |
| CASTOR1 | 8991 |
| RPL34 | 8949 |
| ATP6V1D | 8913 |
| ATP6V1C1 | 8862 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ATP6V1G1 | 10435.0 |
| RPL39L | 10429.0 |
| RPLP1 | 10383.0 |
| RPL19 | 10237.0 |
| RPL27A | 10126.0 |
| RPL38 | 10097.0 |
| RPS12 | 10065.0 |
| RPL27 | 10018.0 |
| RPL12 | 9972.0 |
| RPL5 | 9847.0 |
| RPL10A | 9823.0 |
| RPSA | 9598.0 |
| RPL35A | 9504.0 |
| RPL13 | 9355.0 |
| RPL11 | 9263.0 |
| LAMTOR2 | 9029.0 |
| CASTOR1 | 8991.0 |
| RPL34 | 8949.0 |
| ATP6V1D | 8913.0 |
| ATP6V1C1 | 8862.0 |
| EIF2S2 | 8700.0 |
| LAMTOR4 | 8697.0 |
| DDIT3 | 8615.0 |
| EIF2S1 | 8607.0 |
| RPL36AL | 8546.5 |
| RPL18A | 8433.0 |
| RPS18 | 8418.0 |
| RPL7 | 8407.0 |
| RPS14 | 8367.0 |
| CEBPB | 8342.0 |
| ATP6V1E2 | 8308.0 |
| RPL37 | 8126.0 |
| RPS28 | 8053.0 |
| RPL7A | 7958.0 |
| RPL23 | 7819.0 |
| RPL6 | 7585.0 |
| ASNS | 7511.0 |
| RPL28 | 7492.0 |
| RPLP0 | 7456.0 |
| RPS10 | 7422.0 |
| LAMTOR5 | 7399.0 |
| ATF2 | 7358.0 |
| RPS9 | 7239.0 |
| RPL3 | 7066.0 |
| UBA52 | 6901.0 |
| RPL4 | 6839.0 |
| MIOS | 6786.0 |
| RPL23A | 6780.0 |
| RPS13 | 6745.0 |
| ATP6V1G2 | 6743.0 |
| RPL32 | 6717.0 |
| BMT2 | 6635.0 |
| ATF4 | 6627.0 |
| ATP6V0D2 | 6329.0 |
| RPS21 | 6312.0 |
| RPS27A | 6223.0 |
| RPS23 | 6171.0 |
| RPS2 | 6145.0 |
| RPL8 | 6083.0 |
| RPS3A | 5876.0 |
| ATP6V0E1 | 5840.0 |
| ATP6V0E2 | 5729.0 |
| RPS27L | 5650.0 |
| KICS2 | 5603.0 |
| RPS16 | 5552.0 |
| RPL15 | 5410.0 |
| FAU | 5376.0 |
| RPL18 | 4825.0 |
| CEBPG | 4662.0 |
| RPL26 | 4557.0 |
| ATP6V0C | 4517.0 |
| RPL17 | 4473.0 |
| RPS11 | 4468.0 |
| RPL21 | 4396.0 |
| RPS20 | 4174.0 |
| RPS15A | 4169.0 |
| RPS8 | 4117.0 |
| RPL30 | 3957.0 |
| NPRL2 | 3952.0 |
| RPL26L1 | 3710.0 |
| RPS19 | 3558.0 |
| RPS5 | 3408.0 |
| RPS24 | 3357.0 |
| RPS7 | 3333.0 |
| SESN1 | 3069.0 |
| RPL37A | 3063.0 |
| RPL22 | 2864.0 |
| RPS29 | 2812.0 |
| RPL35 | 2694.0 |
| RPS26 | 2583.0 |
| ATP6V1B2 | 2582.0 |
| FNIP2 | 2386.0 |
| ATF3 | 2309.0 |
| RPS27 | 2232.0 |
| RPS25 | 2059.0 |
| RRAGC | 1990.0 |
| RRAGA | 1886.0 |
| RPL22L1 | 1785.0 |
| RRAGD | 1739.0 |
| IMPACT | 1688.0 |
| FNIP1 | 1570.0 |
| RPS6 | 1237.0 |
| LAMTOR3 | 1190.0 |
| RPL24 | 901.0 |
| ATP6V1A | 718.0 |
| ATP6V1E1 | 596.0 |
| RPLP2 | 141.0 |
| ATP6V1F | -216.0 |
| RPL9 | -399.0 |
| ATP6V0B | -401.0 |
| RHEB | -599.0 |
| RPL29 | -634.0 |
| SEH1L | -682.0 |
| RPL36 | -891.0 |
| ITFG2 | -918.0 |
| RPS3 | -935.0 |
| SESN2 | -1204.0 |
| KPTN | -1638.0 |
| SEC13 | -2354.0 |
| ATP6V1H | -2355.0 |
| RPL41 | -2639.0 |
| RPL13A | -2765.5 |
| RPS15 | -2768.0 |
| ATP6V1G3 | -2787.0 |
| LAMTOR1 | -2877.0 |
| WDR59 | -3177.0 |
| RPL31 | -3475.0 |
| ATP6V1B1 | -3735.0 |
| SLC38A9 | -4527.0 |
| RPL14 | -5770.0 |
| EIF2AK4 | -5914.0 |
| RPTOR | -6584.0 |
| DEPDC5 | -7248.0 |
| ATP6V1C2 | -8320.0 |
| MLST8 | -8336.0 |
| TRIB3 | -8559.0 |
| SH3BP4 | -8720.0 |
| MTOR | -8832.0 |
| TCIRG1 | -8869.0 |
| ATP6V0D1 | -9295.0 |
| FLCN | -9328.0 |
| SZT2 | -9361.0 |
| WDR24 | -9977.0 |
| GCN1 | -10186.0 |
| NPRL3 | -10269.0 |
| RPL3L | -10862.0 |
| RPL10L | -10981.0 |
REACTOME_CELL_CYCLE
| 190 | |
|---|---|
| set | REACTOME_CELL_CYCLE |
| setSize | 666 |
| pANOVA | 7.22e-10 |
| s.dist | 0.14 |
| p.adjustANOVA | 6.97e-08 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| MZT2B | 10648 |
| TUBB8 | 10619 |
| TUBB4B | 10587 |
| CDKN2B | 10441 |
| TUBG1 | 10349 |
| UBB | 10269 |
| TUBG2 | 10264 |
| MZT2A | 10253 |
| CLSPN | 10217 |
| H3C12 | 10132 |
| LIN37 | 10121 |
| ENSA | 10067 |
| NDC80 | 10032 |
| CDK4 | 10023 |
| CKS1B | 9971 |
| PPP2R5B | 9946 |
| GAR1 | 9822 |
| MSH4 | 9802 |
| RFC4 | 9786 |
| TPX2 | 9729 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MZT2B | 10648.0 |
| TUBB8 | 10619.0 |
| TUBB4B | 10587.0 |
| CDKN2B | 10441.0 |
| TUBG1 | 10349.0 |
| UBB | 10269.0 |
| TUBG2 | 10264.0 |
| MZT2A | 10253.0 |
| CLSPN | 10217.0 |
| H3C12 | 10132.0 |
| LIN37 | 10121.0 |
| ENSA | 10067.0 |
| NDC80 | 10032.0 |
| CDK4 | 10023.0 |
| CKS1B | 9971.0 |
| PPP2R5B | 9946.0 |
| GAR1 | 9822.0 |
| MSH4 | 9802.0 |
| RFC4 | 9786.0 |
| TPX2 | 9729.0 |
| PPP6C | 9625.0 |
| RPA2 | 9599.0 |
| AURKB | 9516.0 |
| H2BC14 | 9436.0 |
| TINF2 | 9413.0 |
| H4C8 | 9408.0 |
| RAD1 | 9403.0 |
| TUBA4A | 9371.0 |
| TPR | 9369.0 |
| NUP35 | 9338.0 |
| B9D2 | 9336.0 |
| H2AC14 | 9305.0 |
| KAT5 | 9291.0 |
| PSMB3 | 9282.0 |
| TUBB3 | 9276.0 |
| OIP5 | 9269.0 |
| H2BC17 | 9247.0 |
| NUP107 | 9241.0 |
| H3-3A | 9239.0 |
| HSPA2 | 9216.0 |
| CDK11A | 9204.0 |
| DSCC1 | 9163.0 |
| H3C3 | 9111.0 |
| PSMA6 | 9088.0 |
| NSL1 | 9074.0 |
| POLE3 | 9067.0 |
| STAG3 | 9065.0 |
| E2F5 | 8969.0 |
| GINS2 | 8962.0 |
| PSMA7 | 8947.0 |
| ZWINT | 8941.0 |
| SET | 8922.0 |
| LIN52 | 8899.0 |
| H2AZ1 | 8894.0 |
| PSMC3IP | 8888.0 |
| LPIN2 | 8830.0 |
| POLR2L | 8803.0 |
| CHEK2 | 8765.0 |
| CENPM | 8748.0 |
| PSME2 | 8738.0 |
| NUP43 | 8731.0 |
| PSMC5 | 8695.0 |
| UBC | 8680.0 |
| LMNB1 | 8677.0 |
| PSMA1 | 8676.0 |
| H2BC5 | 8646.0 |
| NCAPH | 8634.0 |
| RBL1 | 8623.0 |
| HMMR | 8621.0 |
| TUBB2B | 8597.0 |
| AJUBA | 8560.0 |
| PRDM9 | 8545.0 |
| POLR2D | 8521.0 |
| POLR2C | 8482.0 |
| YWHAH | 8406.0 |
| ANAPC16 | 8396.0 |
| SKP2 | 8386.0 |
| H4C4 | 8378.0 |
| PSMD12 | 8377.0 |
| TEN1 | 8346.0 |
| CENPL | 8278.0 |
| SPC25 | 8222.0 |
| MCM5 | 8203.0 |
| NUP153 | 8165.0 |
| SMC2 | 8159.0 |
| PSMB1 | 8157.0 |
| MYC | 8099.0 |
| TUBA4B | 8052.0 |
| BANF1 | 8044.0 |
| PSMC4 | 8042.0 |
| KIF23 | 8010.0 |
| FEN1 | 7987.0 |
| TUBB6 | 7982.0 |
| PHLDA1 | 7981.0 |
| H2BC4 | 7968.0 |
| MCM2 | 7892.0 |
| RAB1B | 7855.0 |
| NEDD1 | 7854.0 |
| CTDNEP1 | 7850.0 |
| TERF2IP | 7705.0 |
| PCNA | 7690.0 |
| POLR2I | 7672.0 |
| CCP110 | 7652.0 |
| NUP155 | 7642.0 |
| CENPC | 7622.0 |
| RAB1A | 7593.0 |
| CDK1 | 7556.0 |
| XPO1 | 7555.0 |
| MDM4 | 7548.0 |
| CDKN1B | 7523.0 |
| CEP70 | 7517.0 |
| ZW10 | 7491.0 |
| ORC6 | 7475.0 |
| CHMP2B | 7377.0 |
| CEP135 | 7341.0 |
| MIS18BP1 | 7336.0 |
| DBF4 | 7327.0 |
| POLR2H | 7324.0 |
| MIS18A | 7268.0 |
| H2AC18 | 7261.5 |
| H2AC19 | 7261.5 |
| ANAPC10 | 7259.0 |
| PSMB9 | 7201.0 |
| RAD17 | 7183.0 |
| SKA1 | 7174.0 |
| LYN | 7167.0 |
| MAPRE1 | 7157.0 |
| CTC1 | 7149.0 |
| BORA | 7146.0 |
| ORC1 | 7122.0 |
| POLD4 | 7077.0 |
| H2AC6 | 7006.0 |
| TEX15 | 7001.0 |
| PPP1CB | 6999.0 |
| CDC26 | 6989.0 |
| SIRT2 | 6984.0 |
| UBA52 | 6901.0 |
| TUBA8 | 6874.0 |
| ESCO1 | 6860.0 |
| DSN1 | 6819.0 |
| WEE1 | 6804.0 |
| ANAPC1 | 6773.0 |
| CENPA | 6757.0 |
| H2BC15 | 6756.0 |
| H4C3 | 6755.0 |
| MZT1 | 6742.0 |
| H2BC9 | 6696.5 |
| H3C7 | 6696.5 |
| SPAST | 6615.0 |
| AURKA | 6597.0 |
| H2AC4 | 6574.0 |
| HSP90AB1 | 6482.0 |
| H2AZ2 | 6477.0 |
| H4C5 | 6455.0 |
| LIN54 | 6412.0 |
| BUB1B | 6390.0 |
| HAUS2 | 6338.0 |
| PSMB7 | 6283.0 |
| DYNC1I2 | 6238.0 |
| RPS27A | 6223.0 |
| PSMB10 | 6211.0 |
| CDC25C | 6173.0 |
| BABAM1 | 6143.0 |
| CHMP2A | 6123.0 |
| CDK2 | 6121.0 |
| ITGB3BP | 6053.0 |
| YWHAZ | 6039.0 |
| POLR2E | 6038.0 |
| PSMB8 | 6003.0 |
| NCAPG | 6001.0 |
| E2F6 | 5989.0 |
| PDS5A | 5985.0 |
| KPNB1 | 5984.0 |
| CDKN2D | 5979.0 |
| RBBP8 | 5966.0 |
| RUVBL2 | 5924.0 |
| PSMD13 | 5916.0 |
| DAXX | 5912.0 |
| RBBP4 | 5906.0 |
| SKA2 | 5899.0 |
| REC8 | 5777.0 |
| CDKN2A | 5761.0 |
| NUP54 | 5663.0 |
| EXO1 | 5642.0 |
| CSNK2B | 5641.0 |
| CCNH | 5625.0 |
| SPC24 | 5620.0 |
| HAUS1 | 5604.0 |
| NUP50 | 5527.0 |
| CDC6 | 5425.0 |
| PSMC6 | 5420.0 |
| SKP1 | 5377.0 |
| POLR2K | 5369.0 |
| BRCA1 | 5239.0 |
| GMNN | 5125.0 |
| RPA3 | 5112.0 |
| TOP2A | 5106.0 |
| CNEP1R1 | 5093.0 |
| H2BC3 | 5022.0 |
| PSMA4 | 4963.0 |
| PSMD7 | 4932.0 |
| FBXW11 | 4901.0 |
| PDS5B | 4900.0 |
| CCNB1 | 4895.0 |
| RAB8A | 4863.0 |
| H4C9 | 4853.0 |
| PPP2R5D | 4812.0 |
| CCND3 | 4789.0 |
| HAUS8 | 4763.0 |
| PPME1 | 4739.0 |
| TUBB | 4729.0 |
| USO1 | 4719.0 |
| H4C16 | 4688.0 |
| CENPH | 4681.0 |
| H2AJ | 4666.0 |
| KIF20A | 4654.0 |
| E2F3 | 4591.0 |
| PTTG1 | 4580.0 |
| MRE11 | 4573.0 |
| CEP290 | 4569.0 |
| H2BC6 | 4552.0 |
| MLH1 | 4436.0 |
| SYCE3 | 4417.0 |
| POM121 | 4393.0 |
| POLA2 | 4368.0 |
| SGO2 | 4365.0 |
| FKBPL | 4357.0 |
| MYBL2 | 4319.0 |
| H4C2 | 4300.0 |
| PAFAH1B1 | 4299.0 |
| SGO1 | 4191.0 |
| ABRAXAS1 | 4179.0 |
| SSNA1 | 4164.0 |
| PSMA3 | 4116.0 |
| CDCA5 | 4069.0 |
| H4C6 | 4018.0 |
| GSK3B | 4006.0 |
| RHNO1 | 3991.0 |
| IST1 | 3986.0 |
| KIF18A | 3914.0 |
| RAD51C | 3899.0 |
| TYMS | 3896.0 |
| RBX1 | 3880.0 |
| TNPO1 | 3866.0 |
| CHMP7 | 3806.0 |
| CEP43 | 3778.0 |
| POM121C | 3776.0 |
| CEP63 | 3745.0 |
| RAN | 3664.0 |
| H2BC12 | 3661.0 |
| POLE2 | 3641.0 |
| CENPE | 3612.0 |
| CHMP4C | 3587.0 |
| RFC2 | 3550.0 |
| DYNC1LI1 | 3543.0 |
| ATM | 3539.0 |
| NPM1 | 3501.0 |
| SPO11 | 3481.0 |
| UBE2N | 3457.0 |
| CCNA1 | 3453.0 |
| MIS12 | 3447.0 |
| NUP133 | 3422.0 |
| STN1 | 3401.0 |
| TERF2 | 3331.0 |
| PSMB2 | 3326.0 |
| MAD2L1 | 3317.0 |
| H2AC20 | 3275.0 |
| MDC1 | 3251.0 |
| SMC4 | 3232.0 |
| ATR | 3230.0 |
| PMF1 | 3229.0 |
| TUBA1B | 3208.0 |
| MND1 | 3204.0 |
| NUP205 | 3185.0 |
| CENPQ | 3129.0 |
| AKAP9 | 3085.0 |
| PSMB4 | 3049.0 |
| SMARCA5 | 3044.0 |
| PRIM1 | 3021.0 |
| EML4 | 2994.0 |
| PSMC1 | 2987.0 |
| CEP76 | 2979.0 |
| H3C2 | 2976.0 |
| CEP41 | 2951.0 |
| PRKAR2B | 2917.0 |
| PLK4 | 2895.0 |
| WAPL | 2823.0 |
| CCND2 | 2780.0 |
| WRN | 2771.0 |
| MCM3 | 2768.0 |
| ANKRD28 | 2712.0 |
| ANAPC15 | 2703.0 |
| COP1 | 2697.0 |
| YWHAG | 2674.0 |
| HAUS4 | 2589.0 |
| POT1 | 2588.0 |
| RAD9B | 2575.0 |
| CUL1 | 2567.0 |
| UBE2S | 2530.0 |
| H2BC11 | 2506.0 |
| FBXO5 | 2479.0 |
| CDK6 | 2462.0 |
| MNAT1 | 2449.0 |
| YWHAE | 2415.0 |
| NDC1 | 2410.0 |
| BLM | 2402.0 |
| PSMA8 | 2379.0 |
| UIMC1 | 2348.0 |
| TAOK1 | 2306.0 |
| CDC27 | 2297.0 |
| LEMD3 | 2290.0 |
| TOP3A | 2260.0 |
| DCTN2 | 2252.0 |
| CHMP4B | 2240.0 |
| RPS27 | 2232.0 |
| SHQ1 | 2229.0 |
| RNF8 | 2201.0 |
| PSMD1 | 2144.0 |
| ESCO2 | 2141.0 |
| POLR2G | 2138.0 |
| MAPK1 | 2130.0 |
| PSME4 | 2128.0 |
| WRAP53 | 2126.0 |
| CDCA8 | 2118.0 |
| PSMB5 | 2078.0 |
| CEP152 | 2073.0 |
| HSP90AA1 | 2049.0 |
| ARPP19 | 2036.0 |
| CENPK | 2007.0 |
| CCNB2 | 1987.0 |
| RMI2 | 1950.0 |
| CDC23 | 1913.0 |
| DYNC1I1 | 1903.0 |
| PRIM2 | 1823.0 |
| DMC1 | 1808.0 |
| NUF2 | 1796.0 |
| PPP2R5A | 1763.0 |
| PSMC3 | 1749.0 |
| ZWILCH | 1732.0 |
| CENPT | 1722.0 |
| H2BC21 | 1717.0 |
| ORC2 | 1682.0 |
| NOP10 | 1673.0 |
| SEM1 | 1657.0 |
| PSMC2 | 1653.0 |
| ACTR1A | 1641.0 |
| NEK9 | 1636.0 |
| ANAPC5 | 1528.0 |
| BRIP1 | 1521.0 |
| CDC14A | 1481.0 |
| CDC45 | 1460.0 |
| CEP57 | 1429.0 |
| CLASP2 | 1411.0 |
| RUVBL1 | 1408.0 |
| E2F1 | 1406.0 |
| PSMD4 | 1403.0 |
| ORC3 | 1332.0 |
| ORC4 | 1301.0 |
| ANAPC7 | 1287.0 |
| NUP88 | 1277.0 |
| CENPN | 1269.0 |
| RAE1 | 1215.0 |
| CEP78 | 1192.0 |
| RANBP2 | 1191.0 |
| CEP250 | 1153.0 |
| CCND1 | 1077.0 |
| GINS1 | 995.0 |
| UBE2E1 | 974.0 |
| TERF1 | 948.0 |
| CDK7 | 909.0 |
| TP53 | 830.0 |
| TP53BP1 | 817.0 |
| BUB1 | 814.0 |
| RAD50 | 807.0 |
| RFC5 | 799.0 |
| H2AX | 764.0 |
| PSMA5 | 665.0 |
| NUP160 | 618.0 |
| H3C11 | 608.0 |
| ABL1 | 607.0 |
| MDM2 | 542.0 |
| CCNA2 | 521.0 |
| BLZF1 | 483.0 |
| PSMA2 | 467.0 |
| ALMS1 | 439.0 |
| CDKN2C | 433.0 |
| SUN2 | 432.0 |
| CCNE2 | 369.0 |
| NUP98 | 368.0 |
| TEX12 | 305.0 |
| RFC3 | 297.0 |
| PSMD3 | 274.0 |
| MASTL | 209.0 |
| KNL1 | 199.0 |
| PPP2R1A | 156.0 |
| CLIP1 | 109.0 |
| DIDO1 | 56.0 |
| GINS4 | 26.0 |
| KNTC1 | 17.0 |
| SYCE1 | -60.0 |
| H4C1 | -64.0 |
| RPA1 | -66.0 |
| FOXM1 | -112.0 |
| CENPS | -129.0 |
| ANAPC11 | -133.0 |
| CDC20 | -136.0 |
| VRK1 | -142.0 |
| RB1 | -156.0 |
| RAD21 | -162.0 |
| H3C6 | -174.0 |
| PRKCB | -186.0 |
| PSMD14 | -192.0 |
| BTRC | -218.0 |
| NUDC | -237.0 |
| VRK2 | -276.0 |
| KMT5A | -305.0 |
| TMPO | -330.0 |
| MCM8 | -373.0 |
| CSNK2A1 | -415.0 |
| ORC5 | -485.0 |
| TUBB4A | -521.0 |
| PSME3 | -576.0 |
| H2BC10 | -630.0 |
| SEH1L | -682.0 |
| PLK1 | -736.0 |
| UBE2C | -737.0 |
| SYNE1 | -741.0 |
| NDEL1 | -822.0 |
| PSME1 | -840.0 |
| CHEK1 | -886.0 |
| TFDP2 | -949.0 |
| CDT1 | -1059.0 |
| H3C8 | -1062.0 |
| PSMD6 | -1076.0 |
| YWHAQ | -1078.0 |
| PSMD11 | -1095.0 |
| EP300 | -1121.0 |
| NUP42 | -1128.0 |
| H4C13 | -1134.0 |
| TUBA1A | -1153.0 |
| MCM4 | -1157.0 |
| PKMYT1 | -1216.0 |
| CCNE1 | -1241.0 |
| PPP2CA | -1246.0 |
| RCC2 | -1275.0 |
| BRCA2 | -1342.0 |
| PPP1R12B | -1353.0 |
| DYNLL1 | -1359.0 |
| SDCCAG8 | -1442.0 |
| DYRK1A | -1454.0 |
| PIF1 | -1489.0 |
| STAG1 | -1532.0 |
| NME7 | -1541.0 |
| PSMD5 | -1600.0 |
| AHCTF1 | -1614.0 |
| H3-3B | -1628.0 |
| FBXL7 | -1630.0 |
| SMC1B | -1640.0 |
| NIPBL | -1671.0 |
| CENPU | -1684.0 |
| YWHAB | -1708.0 |
| PSMD8 | -1715.0 |
| CENPF | -1726.0 |
| ANAPC4 | -1773.0 |
| NUP37 | -1790.0 |
| TUBGCP5 | -1801.0 |
| CDC7 | -1848.0 |
| BUB3 | -1861.0 |
| PSMD9 | -1897.0 |
| SMC3 | -1902.0 |
| H4C12 | -1933.0 |
| POLD3 | -1964.0 |
| NHP2 | -1967.0 |
| TK1 | -1981.0 |
| H3C1 | -2029.0 |
| PPP2CB | -2234.0 |
| GTSE1 | -2249.0 |
| RMI1 | -2292.0 |
| KIF2A | -2336.0 |
| SEC13 | -2354.0 |
| DCTN3 | -2491.0 |
| CDC16 | -2545.0 |
| RAD51 | -2618.0 |
| DHFR | -2630.0 |
| TUBB2A | -2758.0 |
| HUS1 | -2809.0 |
| BABAM2 | -2816.0 |
| PHF20 | -2859.0 |
| CENPO | -2939.0 |
| RFC1 | -2949.0 |
| PPP2R5C | -3049.0 |
| TOPBP1 | -3051.0 |
| HAUS3 | -3083.0 |
| NEK7 | -3155.0 |
| CLASP1 | -3176.0 |
| RAB2A | -3216.0 |
| CABLES1 | -3218.0 |
| OPTN | -3285.0 |
| LMNA | -3342.0 |
| PCM1 | -3371.0 |
| H2BC13 | -3416.0 |
| CENPW | -3423.0 |
| RNF168 | -3445.0 |
| CDC25B | -3449.0 |
| RCC1 | -3494.0 |
| CDKN1A | -3505.0 |
| CHMP3 | -3516.0 |
| SUMO1 | -3519.0 |
| TUBGCP3 | -3551.0 |
| CHTF8 | -3584.0 |
| HAUS5 | -3591.0 |
| CENPJ | -3638.0 |
| POLR2B | -3675.0 |
| PRKCA | -3721.0 |
| CSNK1E | -3790.0 |
| CEP192 | -3866.0 |
| CNTRL | -3902.0 |
| LBR | -3946.0 |
| FKBP6 | -3990.0 |
| UBE2V2 | -4004.0 |
| RBL2 | -4030.0 |
| LIN9 | -4051.0 |
| HAUS6 | -4053.0 |
| MLH3 | -4151.0 |
| PSMF1 | -4178.0 |
| H3C4 | -4187.0 |
| CSNK2A2 | -4208.0 |
| H2AC7 | -4211.0 |
| H2BC7 | -4211.0 |
| PPP1R12A | -4220.0 |
| NUMA1 | -4256.0 |
| H2AC8 | -4264.0 |
| CDK11B | -4311.0 |
| MSH5 | -4346.0 |
| LEMD2 | -4384.0 |
| DNA2 | -4453.0 |
| NUP214 | -4467.0 |
| NINL | -4489.0 |
| JAK2 | -4578.0 |
| PPP2R2A | -4580.0 |
| H3-4 | -4629.0 |
| MCM7 | -4806.0 |
| NBN | -4811.0 |
| PPP2R5E | -4824.0 |
| TUBA1C | -4828.0 |
| ACD | -4835.5 |
| NDE1 | -4898.0 |
| CKAP5 | -4910.0 |
| CDK5RAP2 | -4929.0 |
| H2BC8 | -5026.0 |
| AKT3 | -5060.0 |
| CDKN1C | -5192.0 |
| NUP93 | -5201.0 |
| DCTN1 | -5208.0 |
| RAD9A | -5227.0 |
| TUBGCP4 | -5230.0 |
| POLR2F | -5251.0 |
| PPP6R3 | -5254.0 |
| HDAC1 | -5289.0 |
| PSMB6 | -5356.0 |
| E2F2 | -5404.0 |
| FBXL18 | -5409.0 |
| NCAPD3 | -5426.0 |
| DYNC1LI2 | -5447.0 |
| MCPH1 | -5458.0 |
| PIAS4 | -5616.0 |
| UBE2D1 | -5677.0 |
| RTEL1 | -5806.0 |
| CENPP | -5812.0 |
| PPP1CC | -5826.0 |
| BIRC5 | -5845.0 |
| MCM6 | -5942.0 |
| SYCP2 | -6113.0 |
| BARD1 | -6121.0 |
| NUP62 | -6129.0 |
| PSMD2 | -6144.0 |
| PRKACA | -6164.0 |
| RSF1 | -6213.0 |
| GORASP2 | -6220.0 |
| SYCE2 | -6239.0 |
| SPDL1 | -6490.0 |
| NSD2 | -6514.0 |
| CEP131 | -6548.0 |
| MAX | -6665.0 |
| DYNLL2 | -6691.0 |
| MCM10 | -6748.0 |
| POLE4 | -6805.0 |
| HJURP | -6835.0 |
| CHMP4A | -6869.0 |
| POLD1 | -6888.0 |
| SYCP1 | -6902.0 |
| E2F4 | -6907.0 |
| PPP2R1B | -6960.0 |
| LCMT1 | -7001.0 |
| NUP188 | -7120.0 |
| POLE | -7136.0 |
| H2BC26 | -7437.0 |
| TUBAL3 | -7519.0 |
| CDC25A | -7551.0 |
| TUBGCP6 | -7578.0 |
| NCAPD2 | -7592.0 |
| SYNE2 | -7638.0 |
| NEK6 | -7679.0 |
| TUBGCP2 | -7682.0 |
| NCAPG2 | -7697.0 |
| CHMP6 | -7771.0 |
| FZR1 | -7779.0 |
| UBE2I | -7784.0 |
| NUP58 | -7794.0 |
| ZNF385A | -7865.0 |
| CHTF18 | -7905.0 |
| RANGAP1 | -7942.0 |
| VPS4A | -7952.0 |
| CC2D1B | -7972.0 |
| SFI1 | -7974.0 |
| TUBA3C | -7998.0 |
| GOLGA2 | -8023.0 |
| TERT | -8080.0 |
| H2BC1 | -8099.0 |
| LPIN1 | -8128.0 |
| RRM2 | -8159.0 |
| TUBB1 | -8166.0 |
| POLR2A | -8208.0 |
| NUP85 | -8221.0 |
| AAAS | -8286.0 |
| ANKLE2 | -8314.0 |
| POLD2 | -8372.0 |
| SUN1 | -8464.0 |
| NUP210 | -8505.0 |
| NCAPH2 | -8547.0 |
| H3C10 | -8558.0 |
| KIF2C | -8565.0 |
| TUBA3E | -8617.0 |
| ESPL1 | -8663.0 |
| INCENP | -8729.0 |
| CEP164 | -8761.0 |
| PCNT | -8799.0 |
| SFN | -8815.0 |
| MAD1L1 | -8829.0 |
| TFDP1 | -8835.0 |
| GINS3 | -8871.0 |
| NEK2 | -8905.0 |
| PCBP4 | -8914.0 |
| CSNK1D | -9021.0 |
| LIG1 | -9074.0 |
| PPP2R2D | -9167.0 |
| H4C11 | -9168.0 |
| ODF2 | -9272.0 |
| GORASP1 | -9292.0 |
| SRC | -9360.0 |
| CEP72 | -9493.0 |
| DYNC1H1 | -9522.0 |
| ATRIP | -9533.0 |
| ANAPC2 | -9561.0 |
| AKT2 | -9562.0 |
| MAU2 | -9682.0 |
| SYCP3 | -9712.0 |
| MAPK3 | -9797.0 |
| HERC2 | -9902.0 |
| AKT1 | -10034.0 |
| KIF2B | -10419.0 |
| PTK6 | -10535.0 |
| LPIN3 | -10540.0 |
| PSMB11 | -10657.0 |
| TUBA3D | -10666.0 |
| POLR2J | -10901.0 |
REACTOME_RRNA_PROCESSING
| 1148 | |
|---|---|
| set | REACTOME_RRNA_PROCESSING |
| setSize | 192 |
| pANOVA | 1.07e-09 |
| s.dist | 0.255 |
| p.adjustANOVA | 9.78e-08 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL39L | 10429 |
| RPLP1 | 10383 |
| RPL19 | 10237 |
| RRP36 | 10144 |
| RPL27A | 10126 |
| RPL38 | 10097 |
| RPS12 | 10065 |
| RPL27 | 10018 |
| RPL12 | 9972 |
| RPP25 | 9956 |
| MRM1 | 9938 |
| RPL5 | 9847 |
| RPL10A | 9823 |
| GAR1 | 9822 |
| RPSA | 9598 |
| RPL35A | 9504 |
| MPHOSPH10 | 9428 |
| RPL13 | 9355 |
| RPL11 | 9263 |
| EMG1 | 9083 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL39L | 10429.0 |
| RPLP1 | 10383.0 |
| RPL19 | 10237.0 |
| RRP36 | 10144.0 |
| RPL27A | 10126.0 |
| RPL38 | 10097.0 |
| RPS12 | 10065.0 |
| RPL27 | 10018.0 |
| RPL12 | 9972.0 |
| RPP25 | 9956.0 |
| MRM1 | 9938.0 |
| RPL5 | 9847.0 |
| RPL10A | 9823.0 |
| GAR1 | 9822.0 |
| RPSA | 9598.0 |
| RPL35A | 9504.0 |
| MPHOSPH10 | 9428.0 |
| RPL13 | 9355.0 |
| RPL11 | 9263.0 |
| EMG1 | 9083.0 |
| RPL34 | 8949.0 |
| ISG20L2 | 8946.0 |
| RPL36AL | 8546.5 |
| RPL18A | 8433.0 |
| RPS18 | 8418.0 |
| UTP15 | 8413.0 |
| RPL7 | 8407.0 |
| RPP40 | 8373.0 |
| RPS14 | 8367.0 |
| PDCD11 | 8186.0 |
| EXOSC1 | 8143.0 |
| RPL37 | 8126.0 |
| RPS28 | 8053.0 |
| MPHOSPH6 | 7977.0 |
| RPL7A | 7958.0 |
| RRP9 | 7942.0 |
| RPL23 | 7819.0 |
| DDX49 | 7784.0 |
| RPL6 | 7585.0 |
| RPL28 | 7492.0 |
| RPP30 | 7478.0 |
| RPLP0 | 7456.0 |
| EBNA1BP2 | 7448.0 |
| RPS10 | 7422.0 |
| NIP7 | 7371.0 |
| FTSJ3 | 7351.0 |
| EXOSC5 | 7283.0 |
| EXOSC7 | 7271.0 |
| DDX52 | 7242.0 |
| RPS9 | 7239.0 |
| RPL3 | 7066.0 |
| NOL11 | 6973.0 |
| EXOSC3 | 6924.0 |
| UBA52 | 6901.0 |
| RPL4 | 6839.0 |
| RPL23A | 6780.0 |
| RPS13 | 6745.0 |
| RPL32 | 6717.0 |
| DDX21 | 6692.0 |
| DIS3 | 6405.0 |
| WDR3 | 6395.0 |
| RPS21 | 6312.0 |
| RPS27A | 6223.0 |
| EXOSC4 | 6174.0 |
| RPS23 | 6171.0 |
| RPS2 | 6145.0 |
| RPL8 | 6083.0 |
| DCAF13 | 6081.0 |
| UTP11 | 6058.0 |
| EXOSC8 | 5963.0 |
| RPS3A | 5876.0 |
| UTP18 | 5677.0 |
| RPS27L | 5650.0 |
| RPS16 | 5552.0 |
| RPL15 | 5410.0 |
| FAU | 5376.0 |
| RPL18 | 4825.0 |
| RPL26 | 4557.0 |
| RPP38 | 4515.0 |
| RPL17 | 4473.0 |
| RPS11 | 4468.0 |
| RPL21 | 4396.0 |
| PNO1 | 4358.0 |
| RPS20 | 4174.0 |
| RPS15A | 4169.0 |
| RPS8 | 4117.0 |
| FCF1 | 3969.0 |
| RPL30 | 3957.0 |
| BUD23 | 3955.0 |
| NCL | 3954.0 |
| RPL26L1 | 3710.0 |
| DIMT1 | 3607.0 |
| RPS19 | 3558.0 |
| IMP3 | 3475.0 |
| IMP4 | 3465.0 |
| WDR75 | 3416.0 |
| RPS5 | 3408.0 |
| RPS24 | 3357.0 |
| RPS7 | 3333.0 |
| RIOK2 | 3233.0 |
| RPL37A | 3063.0 |
| MTREX | 2997.0 |
| RPL22 | 2864.0 |
| RPS29 | 2812.0 |
| LTV1 | 2704.0 |
| RPL35 | 2694.0 |
| RIOK3 | 2652.0 |
| RPS26 | 2583.0 |
| UTP20 | 2466.0 |
| UTP4 | 2397.0 |
| SENP3 | 2305.0 |
| BYSL | 2302.0 |
| NAT10 | 2275.0 |
| UTP6 | 2239.0 |
| RPS27 | 2232.0 |
| TSR1 | 2106.0 |
| PELP1 | 2083.0 |
| RPS25 | 2059.0 |
| KRR1 | 2025.0 |
| RPL22L1 | 1785.0 |
| NOP10 | 1673.0 |
| WDR43 | 1490.0 |
| RPS6 | 1237.0 |
| NOL12 | 1230.0 |
| PWP2 | 1092.0 |
| RPP21 | 1084.0 |
| RPP14 | 1018.0 |
| UTP25 | 966.0 |
| RPL24 | 901.0 |
| PRORP | 643.0 |
| MTERF4 | 505.0 |
| NOP58 | 358.0 |
| TRMT112 | 296.0 |
| RPLP2 | 141.0 |
| MRM3 | 36.0 |
| NSUN4 | -225.0 |
| RPL9 | -399.0 |
| RPL29 | -634.0 |
| UTP3 | -708.0 |
| RPL36 | -891.0 |
| RPS3 | -935.0 |
| ERI1 | -1151.0 |
| THUMPD1 | -1189.0 |
| RIOK1 | -1831.0 |
| RBM28 | -1859.0 |
| NOP2 | -1886.0 |
| NHP2 | -1967.0 |
| BMS1 | -2070.0 |
| UTP14C | -2301.0 |
| RPL41 | -2639.0 |
| RPL13A | -2765.5 |
| RPS15 | -2768.0 |
| BOP1 | -2773.0 |
| EXOSC9 | -3019.0 |
| WDR12 | -3116.0 |
| RPL31 | -3475.0 |
| GNL3 | -3556.0 |
| CSNK1E | -3790.0 |
| DDX47 | -3839.0 |
| EXOSC2 | -4135.0 |
| SNU13 | -4219.0 |
| WDR46 | -4361.0 |
| XRN2 | -4395.0 |
| NOP56 | -4515.0 |
| PES1 | -4679.0 |
| WDR36 | -4739.0 |
| HEATR1 | -4821.0 |
| C1D | -4987.0 |
| TEX10 | -5260.0 |
| RCL1 | -5420.0 |
| TRMT10C | -5453.0 |
| RPL14 | -5770.0 |
| NOL9 | -5809.0 |
| EXOSC6 | -6161.0 |
| WDR18 | -6243.0 |
| MRM2 | -6261.0 |
| EXOSC10 | -6450.0 |
| NOC4L | -6564.0 |
| DHX37 | -6904.0 |
| NOB1 | -7323.0 |
| RRP7A | -7481.0 |
| FBL | -7753.0 |
| NOP14 | -7895.0 |
| RRP1 | -7909.0 |
| NOL6 | -7992.0 |
| ELAC2 | -8034.0 |
| TSR3 | -8124.0 |
| CSNK1D | -9021.0 |
| TFB1M | -9093.0 |
| RPL3L | -10862.0 |
| TBL3 | -10912.0 |
| RPL10L | -10981.0 |
REACTOME_CELL_CYCLE_MITOTIC
| 1112 | |
|---|---|
| set | REACTOME_CELL_CYCLE_MITOTIC |
| setSize | 539 |
| pANOVA | 2.81e-08 |
| s.dist | 0.14 |
| p.adjustANOVA | 2.43e-06 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| MZT2B | 10648 |
| TUBB8 | 10619 |
| TUBB4B | 10587 |
| CDKN2B | 10441 |
| TUBG1 | 10349 |
| UBB | 10269 |
| TUBG2 | 10264 |
| MZT2A | 10253 |
| H3C12 | 10132 |
| LIN37 | 10121 |
| ENSA | 10067 |
| NDC80 | 10032 |
| CDK4 | 10023 |
| CKS1B | 9971 |
| PPP2R5B | 9946 |
| RFC4 | 9786 |
| TPX2 | 9729 |
| RPA2 | 9599 |
| AURKB | 9516 |
| H2BC14 | 9436 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MZT2B | 10648.0 |
| TUBB8 | 10619.0 |
| TUBB4B | 10587.0 |
| CDKN2B | 10441.0 |
| TUBG1 | 10349.0 |
| UBB | 10269.0 |
| TUBG2 | 10264.0 |
| MZT2A | 10253.0 |
| H3C12 | 10132.0 |
| LIN37 | 10121.0 |
| ENSA | 10067.0 |
| NDC80 | 10032.0 |
| CDK4 | 10023.0 |
| CKS1B | 9971.0 |
| PPP2R5B | 9946.0 |
| RFC4 | 9786.0 |
| TPX2 | 9729.0 |
| RPA2 | 9599.0 |
| AURKB | 9516.0 |
| H2BC14 | 9436.0 |
| H4C8 | 9408.0 |
| TUBA4A | 9371.0 |
| TPR | 9369.0 |
| NUP35 | 9338.0 |
| B9D2 | 9336.0 |
| H2AC14 | 9305.0 |
| PSMB3 | 9282.0 |
| TUBB3 | 9276.0 |
| H2BC17 | 9247.0 |
| NUP107 | 9241.0 |
| H3-3A | 9239.0 |
| CDK11A | 9204.0 |
| H3C3 | 9111.0 |
| PSMA6 | 9088.0 |
| NSL1 | 9074.0 |
| POLE3 | 9067.0 |
| E2F5 | 8969.0 |
| GINS2 | 8962.0 |
| PSMA7 | 8947.0 |
| ZWINT | 8941.0 |
| SET | 8922.0 |
| LIN52 | 8899.0 |
| H2AZ1 | 8894.0 |
| LPIN2 | 8830.0 |
| CENPM | 8748.0 |
| PSME2 | 8738.0 |
| NUP43 | 8731.0 |
| PSMC5 | 8695.0 |
| UBC | 8680.0 |
| LMNB1 | 8677.0 |
| PSMA1 | 8676.0 |
| H2BC5 | 8646.0 |
| NCAPH | 8634.0 |
| RBL1 | 8623.0 |
| HMMR | 8621.0 |
| TUBB2B | 8597.0 |
| AJUBA | 8560.0 |
| ANAPC16 | 8396.0 |
| SKP2 | 8386.0 |
| H4C4 | 8378.0 |
| PSMD12 | 8377.0 |
| CENPL | 8278.0 |
| SPC25 | 8222.0 |
| MCM5 | 8203.0 |
| NUP153 | 8165.0 |
| SMC2 | 8159.0 |
| PSMB1 | 8157.0 |
| MYC | 8099.0 |
| TUBA4B | 8052.0 |
| BANF1 | 8044.0 |
| PSMC4 | 8042.0 |
| KIF23 | 8010.0 |
| FEN1 | 7987.0 |
| TUBB6 | 7982.0 |
| PHLDA1 | 7981.0 |
| H2BC4 | 7968.0 |
| MCM2 | 7892.0 |
| RAB1B | 7855.0 |
| NEDD1 | 7854.0 |
| CTDNEP1 | 7850.0 |
| PCNA | 7690.0 |
| CCP110 | 7652.0 |
| NUP155 | 7642.0 |
| CENPC | 7622.0 |
| RAB1A | 7593.0 |
| CDK1 | 7556.0 |
| XPO1 | 7555.0 |
| CDKN1B | 7523.0 |
| CEP70 | 7517.0 |
| ZW10 | 7491.0 |
| ORC6 | 7475.0 |
| CHMP2B | 7377.0 |
| CEP135 | 7341.0 |
| DBF4 | 7327.0 |
| H2AC18 | 7261.5 |
| H2AC19 | 7261.5 |
| ANAPC10 | 7259.0 |
| PSMB9 | 7201.0 |
| SKA1 | 7174.0 |
| LYN | 7167.0 |
| MAPRE1 | 7157.0 |
| BORA | 7146.0 |
| ORC1 | 7122.0 |
| POLD4 | 7077.0 |
| H2AC6 | 7006.0 |
| PPP1CB | 6999.0 |
| CDC26 | 6989.0 |
| SIRT2 | 6984.0 |
| UBA52 | 6901.0 |
| TUBA8 | 6874.0 |
| ESCO1 | 6860.0 |
| DSN1 | 6819.0 |
| WEE1 | 6804.0 |
| ANAPC1 | 6773.0 |
| CENPA | 6757.0 |
| H2BC15 | 6756.0 |
| H4C3 | 6755.0 |
| MZT1 | 6742.0 |
| H2BC9 | 6696.5 |
| H3C7 | 6696.5 |
| SPAST | 6615.0 |
| AURKA | 6597.0 |
| H2AC4 | 6574.0 |
| HSP90AB1 | 6482.0 |
| H2AZ2 | 6477.0 |
| H4C5 | 6455.0 |
| LIN54 | 6412.0 |
| BUB1B | 6390.0 |
| HAUS2 | 6338.0 |
| PSMB7 | 6283.0 |
| DYNC1I2 | 6238.0 |
| RPS27A | 6223.0 |
| PSMB10 | 6211.0 |
| CDC25C | 6173.0 |
| CHMP2A | 6123.0 |
| CDK2 | 6121.0 |
| ITGB3BP | 6053.0 |
| PSMB8 | 6003.0 |
| NCAPG | 6001.0 |
| E2F6 | 5989.0 |
| PDS5A | 5985.0 |
| KPNB1 | 5984.0 |
| CDKN2D | 5979.0 |
| PSMD13 | 5916.0 |
| RBBP4 | 5906.0 |
| SKA2 | 5899.0 |
| CDKN2A | 5761.0 |
| NUP54 | 5663.0 |
| CSNK2B | 5641.0 |
| CCNH | 5625.0 |
| SPC24 | 5620.0 |
| HAUS1 | 5604.0 |
| NUP50 | 5527.0 |
| CDC6 | 5425.0 |
| PSMC6 | 5420.0 |
| SKP1 | 5377.0 |
| GMNN | 5125.0 |
| RPA3 | 5112.0 |
| TOP2A | 5106.0 |
| CNEP1R1 | 5093.0 |
| H2BC3 | 5022.0 |
| PSMA4 | 4963.0 |
| PSMD7 | 4932.0 |
| FBXW11 | 4901.0 |
| PDS5B | 4900.0 |
| CCNB1 | 4895.0 |
| RAB8A | 4863.0 |
| H4C9 | 4853.0 |
| PPP2R5D | 4812.0 |
| CCND3 | 4789.0 |
| HAUS8 | 4763.0 |
| PPME1 | 4739.0 |
| TUBB | 4729.0 |
| USO1 | 4719.0 |
| H4C16 | 4688.0 |
| CENPH | 4681.0 |
| H2AJ | 4666.0 |
| KIF20A | 4654.0 |
| E2F3 | 4591.0 |
| PTTG1 | 4580.0 |
| CEP290 | 4569.0 |
| H2BC6 | 4552.0 |
| POM121 | 4393.0 |
| POLA2 | 4368.0 |
| SGO2 | 4365.0 |
| FKBPL | 4357.0 |
| MYBL2 | 4319.0 |
| H4C2 | 4300.0 |
| PAFAH1B1 | 4299.0 |
| SGO1 | 4191.0 |
| SSNA1 | 4164.0 |
| PSMA3 | 4116.0 |
| CDCA5 | 4069.0 |
| H4C6 | 4018.0 |
| GSK3B | 4006.0 |
| IST1 | 3986.0 |
| KIF18A | 3914.0 |
| TYMS | 3896.0 |
| RBX1 | 3880.0 |
| TNPO1 | 3866.0 |
| CHMP7 | 3806.0 |
| CEP43 | 3778.0 |
| POM121C | 3776.0 |
| CEP63 | 3745.0 |
| RAN | 3664.0 |
| H2BC12 | 3661.0 |
| POLE2 | 3641.0 |
| CENPE | 3612.0 |
| CHMP4C | 3587.0 |
| RFC2 | 3550.0 |
| DYNC1LI1 | 3543.0 |
| CCNA1 | 3453.0 |
| MIS12 | 3447.0 |
| NUP133 | 3422.0 |
| PSMB2 | 3326.0 |
| MAD2L1 | 3317.0 |
| H2AC20 | 3275.0 |
| SMC4 | 3232.0 |
| PMF1 | 3229.0 |
| TUBA1B | 3208.0 |
| NUP205 | 3185.0 |
| CENPQ | 3129.0 |
| AKAP9 | 3085.0 |
| PSMB4 | 3049.0 |
| PRIM1 | 3021.0 |
| EML4 | 2994.0 |
| PSMC1 | 2987.0 |
| CEP76 | 2979.0 |
| H3C2 | 2976.0 |
| CEP41 | 2951.0 |
| PRKAR2B | 2917.0 |
| PLK4 | 2895.0 |
| WAPL | 2823.0 |
| CCND2 | 2780.0 |
| MCM3 | 2768.0 |
| ANAPC15 | 2703.0 |
| YWHAG | 2674.0 |
| HAUS4 | 2589.0 |
| CUL1 | 2567.0 |
| UBE2S | 2530.0 |
| H2BC11 | 2506.0 |
| FBXO5 | 2479.0 |
| CDK6 | 2462.0 |
| MNAT1 | 2449.0 |
| YWHAE | 2415.0 |
| NDC1 | 2410.0 |
| PSMA8 | 2379.0 |
| TAOK1 | 2306.0 |
| CDC27 | 2297.0 |
| LEMD3 | 2290.0 |
| DCTN2 | 2252.0 |
| CHMP4B | 2240.0 |
| RPS27 | 2232.0 |
| PSMD1 | 2144.0 |
| ESCO2 | 2141.0 |
| MAPK1 | 2130.0 |
| PSME4 | 2128.0 |
| CDCA8 | 2118.0 |
| PSMB5 | 2078.0 |
| CEP152 | 2073.0 |
| HSP90AA1 | 2049.0 |
| ARPP19 | 2036.0 |
| CENPK | 2007.0 |
| CCNB2 | 1987.0 |
| CDC23 | 1913.0 |
| DYNC1I1 | 1903.0 |
| PRIM2 | 1823.0 |
| NUF2 | 1796.0 |
| PPP2R5A | 1763.0 |
| PSMC3 | 1749.0 |
| ZWILCH | 1732.0 |
| CENPT | 1722.0 |
| H2BC21 | 1717.0 |
| ORC2 | 1682.0 |
| SEM1 | 1657.0 |
| PSMC2 | 1653.0 |
| ACTR1A | 1641.0 |
| NEK9 | 1636.0 |
| ANAPC5 | 1528.0 |
| CDC14A | 1481.0 |
| CDC45 | 1460.0 |
| CEP57 | 1429.0 |
| CLASP2 | 1411.0 |
| E2F1 | 1406.0 |
| PSMD4 | 1403.0 |
| ORC3 | 1332.0 |
| ORC4 | 1301.0 |
| ANAPC7 | 1287.0 |
| NUP88 | 1277.0 |
| CENPN | 1269.0 |
| RAE1 | 1215.0 |
| CEP78 | 1192.0 |
| RANBP2 | 1191.0 |
| CEP250 | 1153.0 |
| CCND1 | 1077.0 |
| GINS1 | 995.0 |
| UBE2E1 | 974.0 |
| CDK7 | 909.0 |
| TP53 | 830.0 |
| BUB1 | 814.0 |
| RFC5 | 799.0 |
| H2AX | 764.0 |
| PSMA5 | 665.0 |
| NUP160 | 618.0 |
| H3C11 | 608.0 |
| ABL1 | 607.0 |
| CCNA2 | 521.0 |
| BLZF1 | 483.0 |
| PSMA2 | 467.0 |
| ALMS1 | 439.0 |
| CDKN2C | 433.0 |
| CCNE2 | 369.0 |
| NUP98 | 368.0 |
| RFC3 | 297.0 |
| PSMD3 | 274.0 |
| MASTL | 209.0 |
| KNL1 | 199.0 |
| PPP2R1A | 156.0 |
| CLIP1 | 109.0 |
| GINS4 | 26.0 |
| KNTC1 | 17.0 |
| H4C1 | -64.0 |
| RPA1 | -66.0 |
| FOXM1 | -112.0 |
| CENPS | -129.0 |
| ANAPC11 | -133.0 |
| CDC20 | -136.0 |
| VRK1 | -142.0 |
| RB1 | -156.0 |
| RAD21 | -162.0 |
| H3C6 | -174.0 |
| PRKCB | -186.0 |
| PSMD14 | -192.0 |
| BTRC | -218.0 |
| NUDC | -237.0 |
| VRK2 | -276.0 |
| KMT5A | -305.0 |
| TMPO | -330.0 |
| MCM8 | -373.0 |
| CSNK2A1 | -415.0 |
| ORC5 | -485.0 |
| TUBB4A | -521.0 |
| PSME3 | -576.0 |
| H2BC10 | -630.0 |
| SEH1L | -682.0 |
| PLK1 | -736.0 |
| UBE2C | -737.0 |
| NDEL1 | -822.0 |
| PSME1 | -840.0 |
| TFDP2 | -949.0 |
| CDT1 | -1059.0 |
| H3C8 | -1062.0 |
| PSMD6 | -1076.0 |
| PSMD11 | -1095.0 |
| EP300 | -1121.0 |
| NUP42 | -1128.0 |
| H4C13 | -1134.0 |
| TUBA1A | -1153.0 |
| MCM4 | -1157.0 |
| PKMYT1 | -1216.0 |
| CCNE1 | -1241.0 |
| PPP2CA | -1246.0 |
| RCC2 | -1275.0 |
| PPP1R12B | -1353.0 |
| DYNLL1 | -1359.0 |
| SDCCAG8 | -1442.0 |
| DYRK1A | -1454.0 |
| STAG1 | -1532.0 |
| NME7 | -1541.0 |
| PSMD5 | -1600.0 |
| AHCTF1 | -1614.0 |
| H3-3B | -1628.0 |
| FBXL7 | -1630.0 |
| NIPBL | -1671.0 |
| CENPU | -1684.0 |
| PSMD8 | -1715.0 |
| CENPF | -1726.0 |
| ANAPC4 | -1773.0 |
| NUP37 | -1790.0 |
| TUBGCP5 | -1801.0 |
| CDC7 | -1848.0 |
| BUB3 | -1861.0 |
| PSMD9 | -1897.0 |
| SMC3 | -1902.0 |
| H4C12 | -1933.0 |
| POLD3 | -1964.0 |
| TK1 | -1981.0 |
| H3C1 | -2029.0 |
| PPP2CB | -2234.0 |
| GTSE1 | -2249.0 |
| KIF2A | -2336.0 |
| SEC13 | -2354.0 |
| DCTN3 | -2491.0 |
| CDC16 | -2545.0 |
| DHFR | -2630.0 |
| TUBB2A | -2758.0 |
| CENPO | -2939.0 |
| RFC1 | -2949.0 |
| PPP2R5C | -3049.0 |
| HAUS3 | -3083.0 |
| NEK7 | -3155.0 |
| CLASP1 | -3176.0 |
| RAB2A | -3216.0 |
| CABLES1 | -3218.0 |
| OPTN | -3285.0 |
| LMNA | -3342.0 |
| PCM1 | -3371.0 |
| H2BC13 | -3416.0 |
| CDC25B | -3449.0 |
| RCC1 | -3494.0 |
| CDKN1A | -3505.0 |
| CHMP3 | -3516.0 |
| SUMO1 | -3519.0 |
| TUBGCP3 | -3551.0 |
| HAUS5 | -3591.0 |
| CENPJ | -3638.0 |
| PRKCA | -3721.0 |
| CSNK1E | -3790.0 |
| CEP192 | -3866.0 |
| CNTRL | -3902.0 |
| LBR | -3946.0 |
| RBL2 | -4030.0 |
| LIN9 | -4051.0 |
| HAUS6 | -4053.0 |
| PSMF1 | -4178.0 |
| H3C4 | -4187.0 |
| CSNK2A2 | -4208.0 |
| H2AC7 | -4211.0 |
| H2BC7 | -4211.0 |
| PPP1R12A | -4220.0 |
| NUMA1 | -4256.0 |
| H2AC8 | -4264.0 |
| CDK11B | -4311.0 |
| LEMD2 | -4384.0 |
| DNA2 | -4453.0 |
| NUP214 | -4467.0 |
| NINL | -4489.0 |
| JAK2 | -4578.0 |
| PPP2R2A | -4580.0 |
| H3-4 | -4629.0 |
| MCM7 | -4806.0 |
| PPP2R5E | -4824.0 |
| TUBA1C | -4828.0 |
| NDE1 | -4898.0 |
| CKAP5 | -4910.0 |
| CDK5RAP2 | -4929.0 |
| H2BC8 | -5026.0 |
| AKT3 | -5060.0 |
| CDKN1C | -5192.0 |
| NUP93 | -5201.0 |
| DCTN1 | -5208.0 |
| TUBGCP4 | -5230.0 |
| HDAC1 | -5289.0 |
| PSMB6 | -5356.0 |
| E2F2 | -5404.0 |
| FBXL18 | -5409.0 |
| NCAPD3 | -5426.0 |
| DYNC1LI2 | -5447.0 |
| MCPH1 | -5458.0 |
| UBE2D1 | -5677.0 |
| CENPP | -5812.0 |
| PPP1CC | -5826.0 |
| BIRC5 | -5845.0 |
| MCM6 | -5942.0 |
| NUP62 | -6129.0 |
| PSMD2 | -6144.0 |
| PRKACA | -6164.0 |
| GORASP2 | -6220.0 |
| SPDL1 | -6490.0 |
| CEP131 | -6548.0 |
| MAX | -6665.0 |
| DYNLL2 | -6691.0 |
| MCM10 | -6748.0 |
| POLE4 | -6805.0 |
| CHMP4A | -6869.0 |
| POLD1 | -6888.0 |
| E2F4 | -6907.0 |
| PPP2R1B | -6960.0 |
| LCMT1 | -7001.0 |
| NUP188 | -7120.0 |
| POLE | -7136.0 |
| H2BC26 | -7437.0 |
| TUBAL3 | -7519.0 |
| CDC25A | -7551.0 |
| TUBGCP6 | -7578.0 |
| NCAPD2 | -7592.0 |
| NEK6 | -7679.0 |
| TUBGCP2 | -7682.0 |
| NCAPG2 | -7697.0 |
| CHMP6 | -7771.0 |
| FZR1 | -7779.0 |
| UBE2I | -7784.0 |
| NUP58 | -7794.0 |
| RANGAP1 | -7942.0 |
| VPS4A | -7952.0 |
| CC2D1B | -7972.0 |
| SFI1 | -7974.0 |
| TUBA3C | -7998.0 |
| GOLGA2 | -8023.0 |
| H2BC1 | -8099.0 |
| LPIN1 | -8128.0 |
| RRM2 | -8159.0 |
| TUBB1 | -8166.0 |
| NUP85 | -8221.0 |
| AAAS | -8286.0 |
| ANKLE2 | -8314.0 |
| POLD2 | -8372.0 |
| NUP210 | -8505.0 |
| NCAPH2 | -8547.0 |
| H3C10 | -8558.0 |
| KIF2C | -8565.0 |
| TUBA3E | -8617.0 |
| ESPL1 | -8663.0 |
| INCENP | -8729.0 |
| CEP164 | -8761.0 |
| PCNT | -8799.0 |
| MAD1L1 | -8829.0 |
| TFDP1 | -8835.0 |
| GINS3 | -8871.0 |
| NEK2 | -8905.0 |
| CSNK1D | -9021.0 |
| LIG1 | -9074.0 |
| PPP2R2D | -9167.0 |
| H4C11 | -9168.0 |
| ODF2 | -9272.0 |
| GORASP1 | -9292.0 |
| SRC | -9360.0 |
| CEP72 | -9493.0 |
| DYNC1H1 | -9522.0 |
| ANAPC2 | -9561.0 |
| AKT2 | -9562.0 |
| MAU2 | -9682.0 |
| MAPK3 | -9797.0 |
| AKT1 | -10034.0 |
| KIF2B | -10419.0 |
| PTK6 | -10535.0 |
| LPIN3 | -10540.0 |
| PSMB11 | -10657.0 |
| TUBA3D | -10666.0 |
REACTOME_DNA_REPLICATION_PRE_INITIATION
| 1101 | |
|---|---|
| set | REACTOME_DNA_REPLICATION_PRE_INITIATION |
| setSize | 150 |
| pANOVA | 3e-08 |
| s.dist | 0.262 |
| p.adjustANOVA | 2.46e-06 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| UBB | 10269 |
| H3C12 | 10132 |
| RPA2 | 9599 |
| H2BC14 | 9436 |
| H4C8 | 9408 |
| H2AC14 | 9305 |
| PSMB3 | 9282 |
| H2BC17 | 9247 |
| H3-3A | 9239 |
| H3C3 | 9111 |
| PSMA6 | 9088 |
| POLE3 | 9067 |
| PSMA7 | 8947 |
| H2AZ1 | 8894 |
| PSME2 | 8738 |
| PSMC5 | 8695 |
| UBC | 8680 |
| PSMA1 | 8676 |
| H2BC5 | 8646 |
| ANAPC16 | 8396 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| UBB | 10269.0 |
| H3C12 | 10132.0 |
| RPA2 | 9599.0 |
| H2BC14 | 9436.0 |
| H4C8 | 9408.0 |
| H2AC14 | 9305.0 |
| PSMB3 | 9282.0 |
| H2BC17 | 9247.0 |
| H3-3A | 9239.0 |
| H3C3 | 9111.0 |
| PSMA6 | 9088.0 |
| POLE3 | 9067.0 |
| PSMA7 | 8947.0 |
| H2AZ1 | 8894.0 |
| PSME2 | 8738.0 |
| PSMC5 | 8695.0 |
| UBC | 8680.0 |
| PSMA1 | 8676.0 |
| H2BC5 | 8646.0 |
| ANAPC16 | 8396.0 |
| H4C4 | 8378.0 |
| PSMD12 | 8377.0 |
| MCM5 | 8203.0 |
| PSMB1 | 8157.0 |
| PSMC4 | 8042.0 |
| H2BC4 | 7968.0 |
| MCM2 | 7892.0 |
| ORC6 | 7475.0 |
| DBF4 | 7327.0 |
| H2AC18 | 7261.5 |
| H2AC19 | 7261.5 |
| ANAPC10 | 7259.0 |
| PSMB9 | 7201.0 |
| ORC1 | 7122.0 |
| H2AC6 | 7006.0 |
| CDC26 | 6989.0 |
| UBA52 | 6901.0 |
| ANAPC1 | 6773.0 |
| H2BC15 | 6756.0 |
| H4C3 | 6755.0 |
| H2BC9 | 6696.5 |
| H3C7 | 6696.5 |
| H2AC4 | 6574.0 |
| H2AZ2 | 6477.0 |
| H4C5 | 6455.0 |
| PSMB7 | 6283.0 |
| RPS27A | 6223.0 |
| PSMB10 | 6211.0 |
| CDK2 | 6121.0 |
| PSMB8 | 6003.0 |
| KPNB1 | 5984.0 |
| PSMD13 | 5916.0 |
| CDC6 | 5425.0 |
| PSMC6 | 5420.0 |
| GMNN | 5125.0 |
| RPA3 | 5112.0 |
| H2BC3 | 5022.0 |
| PSMA4 | 4963.0 |
| PSMD7 | 4932.0 |
| H4C9 | 4853.0 |
| H4C16 | 4688.0 |
| H2AJ | 4666.0 |
| H2BC6 | 4552.0 |
| POLA2 | 4368.0 |
| H4C2 | 4300.0 |
| PSMA3 | 4116.0 |
| H4C6 | 4018.0 |
| H2BC12 | 3661.0 |
| POLE2 | 3641.0 |
| PSMB2 | 3326.0 |
| H2AC20 | 3275.0 |
| KPNA6 | 3133.0 |
| PSMB4 | 3049.0 |
| PRIM1 | 3021.0 |
| PSMC1 | 2987.0 |
| H3C2 | 2976.0 |
| MCM3 | 2768.0 |
| ANAPC15 | 2703.0 |
| UBE2S | 2530.0 |
| H2BC11 | 2506.0 |
| CDC27 | 2297.0 |
| PSMD1 | 2144.0 |
| PSMB5 | 2078.0 |
| CDC23 | 1913.0 |
| PRIM2 | 1823.0 |
| PSMC3 | 1749.0 |
| H2BC21 | 1717.0 |
| ORC2 | 1682.0 |
| SEM1 | 1657.0 |
| PSMC2 | 1653.0 |
| ANAPC5 | 1528.0 |
| CDC45 | 1460.0 |
| PSMD4 | 1403.0 |
| ORC3 | 1332.0 |
| ORC4 | 1301.0 |
| ANAPC7 | 1287.0 |
| UBE2E1 | 974.0 |
| H2AX | 764.0 |
| PSMA5 | 665.0 |
| H3C11 | 608.0 |
| PSMA2 | 467.0 |
| PSMD3 | 274.0 |
| H4C1 | -64.0 |
| RPA1 | -66.0 |
| ANAPC11 | -133.0 |
| H3C6 | -174.0 |
| PSMD14 | -192.0 |
| MCM8 | -373.0 |
| ORC5 | -485.0 |
| PSME3 | -576.0 |
| H2BC10 | -630.0 |
| UBE2C | -737.0 |
| PSME1 | -840.0 |
| CDT1 | -1059.0 |
| H3C8 | -1062.0 |
| PSMD6 | -1076.0 |
| PSMD11 | -1095.0 |
| H4C13 | -1134.0 |
| MCM4 | -1157.0 |
| PSMD5 | -1600.0 |
| H3-3B | -1628.0 |
| PSMD8 | -1715.0 |
| ANAPC4 | -1773.0 |
| CDC7 | -1848.0 |
| PSMD9 | -1897.0 |
| H4C12 | -1933.0 |
| H3C1 | -2029.0 |
| CDC16 | -2545.0 |
| KPNA1 | -3299.0 |
| H2BC13 | -3416.0 |
| PSMF1 | -4178.0 |
| H3C4 | -4187.0 |
| H2AC7 | -4211.0 |
| H2BC7 | -4211.0 |
| H2AC8 | -4264.0 |
| MCM7 | -4806.0 |
| H2BC8 | -5026.0 |
| PSMB6 | -5356.0 |
| UBE2D1 | -5677.0 |
| MCM6 | -5942.0 |
| PSMD2 | -6144.0 |
| MCM10 | -6748.0 |
| POLE4 | -6805.0 |
| POLE | -7136.0 |
| H2BC26 | -7437.0 |
| FZR1 | -7779.0 |
| H2BC1 | -8099.0 |
| H3C10 | -8558.0 |
| H4C11 | -9168.0 |
| ANAPC2 | -9561.0 |
REACTOME_DNA_REPLICATION
| 1113 | |
|---|---|
| set | REACTOME_DNA_REPLICATION |
| setSize | 178 |
| pANOVA | 5.43e-08 |
| s.dist | 0.236 |
| p.adjustANOVA | 4.25e-06 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| UBB | 10269 |
| H3C12 | 10132 |
| RFC4 | 9786 |
| RPA2 | 9599 |
| H2BC14 | 9436 |
| H4C8 | 9408 |
| H2AC14 | 9305 |
| PSMB3 | 9282 |
| H2BC17 | 9247 |
| H3-3A | 9239 |
| H3C3 | 9111 |
| PSMA6 | 9088 |
| POLE3 | 9067 |
| GINS2 | 8962 |
| PSMA7 | 8947 |
| H2AZ1 | 8894 |
| PSME2 | 8738 |
| PSMC5 | 8695 |
| UBC | 8680 |
| PSMA1 | 8676 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| UBB | 10269.0 |
| H3C12 | 10132.0 |
| RFC4 | 9786.0 |
| RPA2 | 9599.0 |
| H2BC14 | 9436.0 |
| H4C8 | 9408.0 |
| H2AC14 | 9305.0 |
| PSMB3 | 9282.0 |
| H2BC17 | 9247.0 |
| H3-3A | 9239.0 |
| H3C3 | 9111.0 |
| PSMA6 | 9088.0 |
| POLE3 | 9067.0 |
| GINS2 | 8962.0 |
| PSMA7 | 8947.0 |
| H2AZ1 | 8894.0 |
| PSME2 | 8738.0 |
| PSMC5 | 8695.0 |
| UBC | 8680.0 |
| PSMA1 | 8676.0 |
| H2BC5 | 8646.0 |
| ANAPC16 | 8396.0 |
| SKP2 | 8386.0 |
| H4C4 | 8378.0 |
| PSMD12 | 8377.0 |
| MCM5 | 8203.0 |
| PSMB1 | 8157.0 |
| PSMC4 | 8042.0 |
| FEN1 | 7987.0 |
| H2BC4 | 7968.0 |
| MCM2 | 7892.0 |
| PCNA | 7690.0 |
| ORC6 | 7475.0 |
| DBF4 | 7327.0 |
| H2AC18 | 7261.5 |
| H2AC19 | 7261.5 |
| ANAPC10 | 7259.0 |
| PSMB9 | 7201.0 |
| ORC1 | 7122.0 |
| POLD4 | 7077.0 |
| H2AC6 | 7006.0 |
| CDC26 | 6989.0 |
| UBA52 | 6901.0 |
| ANAPC1 | 6773.0 |
| H2BC15 | 6756.0 |
| H4C3 | 6755.0 |
| H2BC9 | 6696.5 |
| H3C7 | 6696.5 |
| H2AC4 | 6574.0 |
| H2AZ2 | 6477.0 |
| H4C5 | 6455.0 |
| PSMB7 | 6283.0 |
| RPS27A | 6223.0 |
| PSMB10 | 6211.0 |
| CDK2 | 6121.0 |
| PSMB8 | 6003.0 |
| KPNB1 | 5984.0 |
| PSMD13 | 5916.0 |
| CDC6 | 5425.0 |
| PSMC6 | 5420.0 |
| SKP1 | 5377.0 |
| GMNN | 5125.0 |
| RPA3 | 5112.0 |
| H2BC3 | 5022.0 |
| PSMA4 | 4963.0 |
| PSMD7 | 4932.0 |
| H4C9 | 4853.0 |
| H4C16 | 4688.0 |
| H2AJ | 4666.0 |
| H2BC6 | 4552.0 |
| POLA2 | 4368.0 |
| H4C2 | 4300.0 |
| PSMA3 | 4116.0 |
| H4C6 | 4018.0 |
| RBX1 | 3880.0 |
| H2BC12 | 3661.0 |
| POLE2 | 3641.0 |
| RFC2 | 3550.0 |
| CCNA1 | 3453.0 |
| PSMB2 | 3326.0 |
| H2AC20 | 3275.0 |
| KPNA6 | 3133.0 |
| PSMB4 | 3049.0 |
| PRIM1 | 3021.0 |
| PSMC1 | 2987.0 |
| H3C2 | 2976.0 |
| MCM3 | 2768.0 |
| ANAPC15 | 2703.0 |
| CUL1 | 2567.0 |
| UBE2S | 2530.0 |
| H2BC11 | 2506.0 |
| PSMA8 | 2379.0 |
| CDC27 | 2297.0 |
| PSMD1 | 2144.0 |
| PSME4 | 2128.0 |
| PSMB5 | 2078.0 |
| CDC23 | 1913.0 |
| PRIM2 | 1823.0 |
| PSMC3 | 1749.0 |
| H2BC21 | 1717.0 |
| ORC2 | 1682.0 |
| SEM1 | 1657.0 |
| PSMC2 | 1653.0 |
| ANAPC5 | 1528.0 |
| CDC45 | 1460.0 |
| PSMD4 | 1403.0 |
| ORC3 | 1332.0 |
| ORC4 | 1301.0 |
| ANAPC7 | 1287.0 |
| GINS1 | 995.0 |
| UBE2E1 | 974.0 |
| RFC5 | 799.0 |
| H2AX | 764.0 |
| PSMA5 | 665.0 |
| H3C11 | 608.0 |
| CCNA2 | 521.0 |
| PSMA2 | 467.0 |
| CCNE2 | 369.0 |
| RFC3 | 297.0 |
| PSMD3 | 274.0 |
| GINS4 | 26.0 |
| H4C1 | -64.0 |
| RPA1 | -66.0 |
| ANAPC11 | -133.0 |
| H3C6 | -174.0 |
| PSMD14 | -192.0 |
| MCM8 | -373.0 |
| ORC5 | -485.0 |
| PSME3 | -576.0 |
| H2BC10 | -630.0 |
| UBE2C | -737.0 |
| PSME1 | -840.0 |
| CDT1 | -1059.0 |
| H3C8 | -1062.0 |
| PSMD6 | -1076.0 |
| PSMD11 | -1095.0 |
| H4C13 | -1134.0 |
| MCM4 | -1157.0 |
| CCNE1 | -1241.0 |
| PSMD5 | -1600.0 |
| H3-3B | -1628.0 |
| PSMD8 | -1715.0 |
| ANAPC4 | -1773.0 |
| CDC7 | -1848.0 |
| PSMD9 | -1897.0 |
| H4C12 | -1933.0 |
| POLD3 | -1964.0 |
| H3C1 | -2029.0 |
| CDC16 | -2545.0 |
| RFC1 | -2949.0 |
| KPNA1 | -3299.0 |
| H2BC13 | -3416.0 |
| PSMF1 | -4178.0 |
| H3C4 | -4187.0 |
| H2AC7 | -4211.0 |
| H2BC7 | -4211.0 |
| H2AC8 | -4264.0 |
| DNA2 | -4453.0 |
| MCM7 | -4806.0 |
| H2BC8 | -5026.0 |
| PSMB6 | -5356.0 |
| UBE2D1 | -5677.0 |
| MCM6 | -5942.0 |
| PSMD2 | -6144.0 |
| MCM10 | -6748.0 |
| POLE4 | -6805.0 |
| POLD1 | -6888.0 |
| POLE | -7136.0 |
| H2BC26 | -7437.0 |
| FZR1 | -7779.0 |
| H2BC1 | -8099.0 |
| POLD2 | -8372.0 |
| H3C10 | -8558.0 |
| GINS3 | -8871.0 |
| LIG1 | -9074.0 |
| H4C11 | -9168.0 |
| ANAPC2 | -9561.0 |
| PSMB11 | -10657.0 |
REACTOME_MITOCHONDRIAL_TRANSLATION
| 874 | |
|---|---|
| set | REACTOME_MITOCHONDRIAL_TRANSLATION |
| setSize | 93 |
| pANOVA | 1.34e-07 |
| s.dist | 0.316 |
| p.adjustANOVA | 9.91e-06 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CHCHD1 | 10402 |
| MRPL53 | 10073 |
| MRPL9 | 9777 |
| MRPL16 | 9735 |
| MRPL33 | 9537 |
| MTIF2 | 9535 |
| MRPL12 | 9513 |
| MRPL39 | 9512 |
| MRPL17 | 9402 |
| MRPL37 | 9347 |
| MRPL57 | 9283 |
| MRPS16 | 8881 |
| MRPL27 | 8779 |
| MRPL19 | 8606 |
| TUFM | 8502 |
| MRPS11 | 8329 |
| MRPL30 | 8313 |
| MRPL11 | 8262 |
| MRPS7 | 8128 |
| GFM1 | 8025 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CHCHD1 | 10402 |
| MRPL53 | 10073 |
| MRPL9 | 9777 |
| MRPL16 | 9735 |
| MRPL33 | 9537 |
| MTIF2 | 9535 |
| MRPL12 | 9513 |
| MRPL39 | 9512 |
| MRPL17 | 9402 |
| MRPL37 | 9347 |
| MRPL57 | 9283 |
| MRPS16 | 8881 |
| MRPL27 | 8779 |
| MRPL19 | 8606 |
| TUFM | 8502 |
| MRPS11 | 8329 |
| MRPL30 | 8313 |
| MRPL11 | 8262 |
| MRPS7 | 8128 |
| GFM1 | 8025 |
| MRPS12 | 8009 |
| MRPS9 | 8006 |
| MRPL34 | 7304 |
| MRPL36 | 7032 |
| MRPS15 | 6903 |
| MRPL54 | 6785 |
| MRPL46 | 6781 |
| MRPL50 | 6723 |
| MRPS17 | 6590 |
| MRPL42 | 6514 |
| MTIF3 | 6487 |
| MRPL40 | 6374 |
| MTRF1L | 6362 |
| MRPL18 | 6071 |
| MRPL51 | 5803 |
| MRPL10 | 5637 |
| MRPL24 | 5568 |
| OXA1L | 5550 |
| MRPL41 | 5416 |
| MRPL48 | 5398 |
| MRPS30 | 5321 |
| MRPL21 | 5072 |
| PTCD3 | 5058 |
| MRPS18B | 4983 |
| MRPS31 | 4881 |
| MRPS18A | 4762 |
| MRPL2 | 4587 |
| MRPS34 | 3939 |
| MRPL49 | 3773 |
| MRPL47 | 3144 |
| MRPL32 | 2795 |
| MRPL44 | 2765 |
| MRPS22 | 2657 |
| MRPL15 | 2223 |
| MRPS24 | 2005 |
| AURKAIP1 | 1928 |
| MRPL22 | 1751 |
| DAP3 | 1744 |
| MRPS5 | 1711 |
| MRPL20 | 1351 |
| MRPL52 | 1112 |
| MRPS35 | 1015 |
| MRPL45 | 865 |
| MRPS25 | 796 |
| MRPS18C | 702 |
| GADD45GIP1 | 678 |
| MRPL3 | 579 |
| MRPS23 | 488 |
| MRPS28 | -257 |
| MRPS26 | -626 |
| MRPS6 | -700 |
| MRPL14 | -1050 |
| MRPL28 | -1679 |
| MRPL13 | -1774 |
| MRPL1 | -1960 |
| MRPS27 | -2079 |
| GFM2 | -2086 |
| MRPS10 | -2284 |
| MRPL58 | -3033 |
| MRPL43 | -3053 |
| MRPS33 | -3305 |
| MRPL55 | -3401 |
| MRPL4 | -3483 |
| MTFMT | -3793 |
| ERAL1 | -3900 |
| MRPL35 | -3947 |
| TSFM | -3971 |
| MRRF | -4195 |
| MRPS2 | -4820 |
| MRPS21 | -5738 |
| MRPL38 | -8236 |
| MRPS14 | -8328 |
| MRPL23 | -8657 |
REACTOME_CELL_CYCLE_CHECKPOINTS
| 1120 | |
|---|---|
| set | REACTOME_CELL_CYCLE_CHECKPOINTS |
| setSize | 284 |
| pANOVA | 1.39e-07 |
| s.dist | 0.182 |
| p.adjustANOVA | 9.91e-06 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| UBB | 10269 |
| CLSPN | 10217 |
| NDC80 | 10032 |
| PPP2R5B | 9946 |
| RFC4 | 9786 |
| RPA2 | 9599 |
| AURKB | 9516 |
| H2BC14 | 9436 |
| H4C8 | 9408 |
| RAD1 | 9403 |
| B9D2 | 9336 |
| KAT5 | 9291 |
| PSMB3 | 9282 |
| H2BC17 | 9247 |
| NUP107 | 9241 |
| PSMA6 | 9088 |
| NSL1 | 9074 |
| PSMA7 | 8947 |
| ZWINT | 8941 |
| CHEK2 | 8765 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| UBB | 10269.0 |
| CLSPN | 10217.0 |
| NDC80 | 10032.0 |
| PPP2R5B | 9946.0 |
| RFC4 | 9786.0 |
| RPA2 | 9599.0 |
| AURKB | 9516.0 |
| H2BC14 | 9436.0 |
| H4C8 | 9408.0 |
| RAD1 | 9403.0 |
| B9D2 | 9336.0 |
| KAT5 | 9291.0 |
| PSMB3 | 9282.0 |
| H2BC17 | 9247.0 |
| NUP107 | 9241.0 |
| PSMA6 | 9088.0 |
| NSL1 | 9074.0 |
| PSMA7 | 8947.0 |
| ZWINT | 8941.0 |
| CHEK2 | 8765.0 |
| CENPM | 8748.0 |
| PSME2 | 8738.0 |
| NUP43 | 8731.0 |
| PSMC5 | 8695.0 |
| UBC | 8680.0 |
| PSMA1 | 8676.0 |
| H2BC5 | 8646.0 |
| YWHAH | 8406.0 |
| ANAPC16 | 8396.0 |
| H4C4 | 8378.0 |
| PSMD12 | 8377.0 |
| CENPL | 8278.0 |
| SPC25 | 8222.0 |
| MCM5 | 8203.0 |
| PSMB1 | 8157.0 |
| PSMC4 | 8042.0 |
| H2BC4 | 7968.0 |
| MCM2 | 7892.0 |
| CENPC | 7622.0 |
| CDK1 | 7556.0 |
| XPO1 | 7555.0 |
| MDM4 | 7548.0 |
| CDKN1B | 7523.0 |
| ZW10 | 7491.0 |
| ORC6 | 7475.0 |
| DBF4 | 7327.0 |
| ANAPC10 | 7259.0 |
| PSMB9 | 7201.0 |
| RAD17 | 7183.0 |
| SKA1 | 7174.0 |
| MAPRE1 | 7157.0 |
| ORC1 | 7122.0 |
| CDC26 | 6989.0 |
| UBA52 | 6901.0 |
| DSN1 | 6819.0 |
| WEE1 | 6804.0 |
| ANAPC1 | 6773.0 |
| CENPA | 6757.0 |
| H2BC15 | 6756.0 |
| H4C3 | 6755.0 |
| H2BC9 | 6696.5 |
| H4C5 | 6455.0 |
| BUB1B | 6390.0 |
| PSMB7 | 6283.0 |
| DYNC1I2 | 6238.0 |
| RPS27A | 6223.0 |
| PSMB10 | 6211.0 |
| CDC25C | 6173.0 |
| BABAM1 | 6143.0 |
| CDK2 | 6121.0 |
| ITGB3BP | 6053.0 |
| YWHAZ | 6039.0 |
| PSMB8 | 6003.0 |
| RBBP8 | 5966.0 |
| PSMD13 | 5916.0 |
| SKA2 | 5899.0 |
| CDKN2A | 5761.0 |
| EXO1 | 5642.0 |
| SPC24 | 5620.0 |
| CDC6 | 5425.0 |
| PSMC6 | 5420.0 |
| BRCA1 | 5239.0 |
| RPA3 | 5112.0 |
| H2BC3 | 5022.0 |
| PSMA4 | 4963.0 |
| PSMD7 | 4932.0 |
| CCNB1 | 4895.0 |
| H4C9 | 4853.0 |
| PPP2R5D | 4812.0 |
| H4C16 | 4688.0 |
| CENPH | 4681.0 |
| MRE11 | 4573.0 |
| H2BC6 | 4552.0 |
| SGO2 | 4365.0 |
| H4C2 | 4300.0 |
| PAFAH1B1 | 4299.0 |
| SGO1 | 4191.0 |
| ABRAXAS1 | 4179.0 |
| PSMA3 | 4116.0 |
| H4C6 | 4018.0 |
| RHNO1 | 3991.0 |
| KIF18A | 3914.0 |
| H2BC12 | 3661.0 |
| CENPE | 3612.0 |
| RFC2 | 3550.0 |
| DYNC1LI1 | 3543.0 |
| ATM | 3539.0 |
| UBE2N | 3457.0 |
| CCNA1 | 3453.0 |
| MIS12 | 3447.0 |
| NUP133 | 3422.0 |
| PSMB2 | 3326.0 |
| MAD2L1 | 3317.0 |
| MDC1 | 3251.0 |
| ATR | 3230.0 |
| PMF1 | 3229.0 |
| CENPQ | 3129.0 |
| PSMB4 | 3049.0 |
| PSMC1 | 2987.0 |
| WRN | 2771.0 |
| MCM3 | 2768.0 |
| ANAPC15 | 2703.0 |
| COP1 | 2697.0 |
| YWHAG | 2674.0 |
| RAD9B | 2575.0 |
| UBE2S | 2530.0 |
| H2BC11 | 2506.0 |
| YWHAE | 2415.0 |
| BLM | 2402.0 |
| PSMA8 | 2379.0 |
| UIMC1 | 2348.0 |
| TAOK1 | 2306.0 |
| CDC27 | 2297.0 |
| TOP3A | 2260.0 |
| RPS27 | 2232.0 |
| RNF8 | 2201.0 |
| PSMD1 | 2144.0 |
| PSME4 | 2128.0 |
| CDCA8 | 2118.0 |
| PSMB5 | 2078.0 |
| CENPK | 2007.0 |
| CCNB2 | 1987.0 |
| RMI2 | 1950.0 |
| CDC23 | 1913.0 |
| DYNC1I1 | 1903.0 |
| NUF2 | 1796.0 |
| PPP2R5A | 1763.0 |
| PSMC3 | 1749.0 |
| ZWILCH | 1732.0 |
| CENPT | 1722.0 |
| H2BC21 | 1717.0 |
| ORC2 | 1682.0 |
| SEM1 | 1657.0 |
| PSMC2 | 1653.0 |
| ANAPC5 | 1528.0 |
| BRIP1 | 1521.0 |
| CDC45 | 1460.0 |
| CLASP2 | 1411.0 |
| PSMD4 | 1403.0 |
| ORC3 | 1332.0 |
| ORC4 | 1301.0 |
| ANAPC7 | 1287.0 |
| CENPN | 1269.0 |
| RANBP2 | 1191.0 |
| UBE2E1 | 974.0 |
| TP53 | 830.0 |
| TP53BP1 | 817.0 |
| BUB1 | 814.0 |
| RAD50 | 807.0 |
| RFC5 | 799.0 |
| H2AX | 764.0 |
| PSMA5 | 665.0 |
| NUP160 | 618.0 |
| MDM2 | 542.0 |
| CCNA2 | 521.0 |
| PSMA2 | 467.0 |
| CCNE2 | 369.0 |
| NUP98 | 368.0 |
| RFC3 | 297.0 |
| PSMD3 | 274.0 |
| KNL1 | 199.0 |
| PPP2R1A | 156.0 |
| CLIP1 | 109.0 |
| KNTC1 | 17.0 |
| H4C1 | -64.0 |
| RPA1 | -66.0 |
| CENPS | -129.0 |
| ANAPC11 | -133.0 |
| CDC20 | -136.0 |
| PSMD14 | -192.0 |
| NUDC | -237.0 |
| MCM8 | -373.0 |
| ORC5 | -485.0 |
| PSME3 | -576.0 |
| H2BC10 | -630.0 |
| SEH1L | -682.0 |
| PLK1 | -736.0 |
| UBE2C | -737.0 |
| NDEL1 | -822.0 |
| PSME1 | -840.0 |
| CHEK1 | -886.0 |
| PSMD6 | -1076.0 |
| YWHAQ | -1078.0 |
| PSMD11 | -1095.0 |
| H4C13 | -1134.0 |
| MCM4 | -1157.0 |
| PKMYT1 | -1216.0 |
| CCNE1 | -1241.0 |
| PPP2CA | -1246.0 |
| RCC2 | -1275.0 |
| DYNLL1 | -1359.0 |
| PSMD5 | -1600.0 |
| AHCTF1 | -1614.0 |
| CENPU | -1684.0 |
| YWHAB | -1708.0 |
| PSMD8 | -1715.0 |
| CENPF | -1726.0 |
| ANAPC4 | -1773.0 |
| NUP37 | -1790.0 |
| CDC7 | -1848.0 |
| BUB3 | -1861.0 |
| PSMD9 | -1897.0 |
| H4C12 | -1933.0 |
| PPP2CB | -2234.0 |
| GTSE1 | -2249.0 |
| RMI1 | -2292.0 |
| KIF2A | -2336.0 |
| SEC13 | -2354.0 |
| CDC16 | -2545.0 |
| HUS1 | -2809.0 |
| BABAM2 | -2816.0 |
| PHF20 | -2859.0 |
| CENPO | -2939.0 |
| PPP2R5C | -3049.0 |
| TOPBP1 | -3051.0 |
| CLASP1 | -3176.0 |
| H2BC13 | -3416.0 |
| RNF168 | -3445.0 |
| CDKN1A | -3505.0 |
| UBE2V2 | -4004.0 |
| PSMF1 | -4178.0 |
| H2BC7 | -4211.0 |
| DNA2 | -4453.0 |
| H3-4 | -4629.0 |
| MCM7 | -4806.0 |
| NBN | -4811.0 |
| PPP2R5E | -4824.0 |
| NDE1 | -4898.0 |
| CKAP5 | -4910.0 |
| H2BC8 | -5026.0 |
| RAD9A | -5227.0 |
| PSMB6 | -5356.0 |
| DYNC1LI2 | -5447.0 |
| PIAS4 | -5616.0 |
| UBE2D1 | -5677.0 |
| CENPP | -5812.0 |
| PPP1CC | -5826.0 |
| BIRC5 | -5845.0 |
| MCM6 | -5942.0 |
| BARD1 | -6121.0 |
| PSMD2 | -6144.0 |
| SPDL1 | -6490.0 |
| NSD2 | -6514.0 |
| DYNLL2 | -6691.0 |
| MCM10 | -6748.0 |
| PPP2R1B | -6960.0 |
| H2BC26 | -7437.0 |
| CDC25A | -7551.0 |
| ZNF385A | -7865.0 |
| RANGAP1 | -7942.0 |
| H2BC1 | -8099.0 |
| NUP85 | -8221.0 |
| KIF2C | -8565.0 |
| INCENP | -8729.0 |
| SFN | -8815.0 |
| MAD1L1 | -8829.0 |
| PCBP4 | -8914.0 |
| H4C11 | -9168.0 |
| DYNC1H1 | -9522.0 |
| ATRIP | -9533.0 |
| ANAPC2 | -9561.0 |
| HERC2 | -9902.0 |
| KIF2B | -10419.0 |
| PSMB11 | -10657.0 |
REACTOME_SARS_COV_1_HOST_INTERACTIONS
| 1550 | |
|---|---|
| set | REACTOME_SARS_COV_1_HOST_INTERACTIONS |
| setSize | 92 |
| pANOVA | 3.64e-07 |
| s.dist | 0.307 |
| p.adjustANOVA | 2.49e-05 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| UBB | 10269 |
| RPS12 | 10065 |
| TOMM70 | 9733 |
| PYCARD | 9642 |
| RPSA | 9598 |
| EEF1A1 | 9508 |
| RCAN3 | 9132 |
| NFKBIA | 9116 |
| IFIH1 | 8998 |
| UBC | 8680 |
| RPS18 | 8418 |
| YWHAH | 8406 |
| IRF3 | 8402 |
| RPS14 | 8367 |
| RIPK3 | 8285 |
| PCBP2 | 8264 |
| CAV1 | 8242 |
| SIKE1 | 8122 |
| PPIH | 8060 |
| RPS28 | 8053 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| UBB | 10269 |
| RPS12 | 10065 |
| TOMM70 | 9733 |
| PYCARD | 9642 |
| RPSA | 9598 |
| EEF1A1 | 9508 |
| RCAN3 | 9132 |
| NFKBIA | 9116 |
| IFIH1 | 8998 |
| UBC | 8680 |
| RPS18 | 8418 |
| YWHAH | 8406 |
| IRF3 | 8402 |
| RPS14 | 8367 |
| RIPK3 | 8285 |
| PCBP2 | 8264 |
| CAV1 | 8242 |
| SIKE1 | 8122 |
| PPIH | 8060 |
| RPS28 | 8053 |
| SP1 | 7917 |
| PPIG | 7844 |
| RPS10 | 7422 |
| RPS9 | 7239 |
| HNRNPA1 | 6967 |
| UBA52 | 6901 |
| RPS13 | 6745 |
| SMAD4 | 6630 |
| FKBP1A | 6399 |
| RPS21 | 6312 |
| RPS27A | 6223 |
| RPS23 | 6171 |
| RPS2 | 6145 |
| YWHAZ | 6039 |
| KPNB1 | 5984 |
| RPS3A | 5876 |
| RPS27L | 5650 |
| RPS16 | 5552 |
| PSMC6 | 5420 |
| FAU | 5376 |
| IRAK2 | 5303 |
| PPIB | 4755 |
| SERPINE1 | 4724 |
| ITCH | 4511 |
| PPIA | 4505 |
| RPS11 | 4468 |
| TBK1 | 4287 |
| RPS20 | 4174 |
| RPS15A | 4169 |
| RPS8 | 4117 |
| NMI | 4102 |
| PALS1 | 3977 |
| RPS19 | 3558 |
| NPM1 | 3501 |
| RPS5 | 3408 |
| RPS24 | 3357 |
| RPS7 | 3333 |
| RPS29 | 2812 |
| YWHAG | 2674 |
| RPS26 | 2583 |
| YWHAE | 2415 |
| RPS27 | 2232 |
| RPS25 | 2059 |
| RPS6 | 1237 |
| BCL2L1 | 707 |
| BST2 | 636 |
| NFKB1 | 12 |
| RPS3 | -935 |
| KPNA2 | -967 |
| YWHAQ | -1078 |
| EP300 | -1121 |
| YWHAB | -1708 |
| CASP1 | -2295 |
| MAVS | -2509 |
| RIGI | -2535 |
| TRAF6 | -2592 |
| RPS15 | -2768 |
| TKFC | -2784 |
| TRIM25 | -3391 |
| NLRP3 | -3412 |
| STING1 | -3751 |
| TRAF3 | -5135 |
| IKBKE | -5538 |
| RUNX1 | -5564 |
| PDPK1 | -5927 |
| RELA | -6000 |
| SMAD3 | -7487 |
| UBE2I | -7784 |
| RIPK1 | -7795 |
| PKLR | -7988 |
| SFN | -8815 |
| SFTPD | -9151 |
REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_HSCS
| 1282 | |
|---|---|
| set | REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_HSCS |
| setSize | 121 |
| pANOVA | 4.35e-07 |
| s.dist | 0.266 |
| p.adjustANOVA | 2.86e-05 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| UBB | 10269 |
| H3C12 | 10132 |
| LMO2 | 9518 |
| H2BC14 | 9436 |
| H4C8 | 9408 |
| H2AC14 | 9305 |
| PSMB3 | 9282 |
| H2BC17 | 9247 |
| H3-3A | 9239 |
| H3C3 | 9111 |
| PSMA6 | 9088 |
| GATA2 | 9063 |
| PSMA7 | 8947 |
| H2AZ1 | 8894 |
| PSME2 | 8738 |
| PSMC5 | 8695 |
| UBC | 8680 |
| PSMA1 | 8676 |
| H2BC5 | 8646 |
| H4C4 | 8378 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| UBB | 10269.0 |
| H3C12 | 10132.0 |
| LMO2 | 9518.0 |
| H2BC14 | 9436.0 |
| H4C8 | 9408.0 |
| H2AC14 | 9305.0 |
| PSMB3 | 9282.0 |
| H2BC17 | 9247.0 |
| H3-3A | 9239.0 |
| H3C3 | 9111.0 |
| PSMA6 | 9088.0 |
| GATA2 | 9063.0 |
| PSMA7 | 8947.0 |
| H2AZ1 | 8894.0 |
| PSME2 | 8738.0 |
| PSMC5 | 8695.0 |
| UBC | 8680.0 |
| PSMA1 | 8676.0 |
| H2BC5 | 8646.0 |
| H4C4 | 8378.0 |
| PSMD12 | 8377.0 |
| PSMB1 | 8157.0 |
| MYB | 8134.0 |
| PSMC4 | 8042.0 |
| LDB1 | 8039.0 |
| H2BC4 | 7968.0 |
| H2AC18 | 7261.5 |
| H2AC19 | 7261.5 |
| PSMB9 | 7201.0 |
| H2AC6 | 7006.0 |
| UBA52 | 6901.0 |
| H2BC15 | 6756.0 |
| H4C3 | 6755.0 |
| H2BC9 | 6696.5 |
| H3C7 | 6696.5 |
| H2AC4 | 6574.0 |
| H2AZ2 | 6477.0 |
| H4C5 | 6455.0 |
| PSMB7 | 6283.0 |
| RPS27A | 6223.0 |
| PSMB10 | 6211.0 |
| PSMB8 | 6003.0 |
| PSMD13 | 5916.0 |
| CCNH | 5625.0 |
| PSMC6 | 5420.0 |
| H2BC3 | 5022.0 |
| PSMA4 | 4963.0 |
| PSMD7 | 4932.0 |
| H4C9 | 4853.0 |
| H4C16 | 4688.0 |
| H2AJ | 4666.0 |
| H2BC6 | 4552.0 |
| ITCH | 4511.0 |
| H4C2 | 4300.0 |
| PSMA3 | 4116.0 |
| H4C6 | 4018.0 |
| KMT2A | 3940.0 |
| H2BC12 | 3661.0 |
| PSMB2 | 3326.0 |
| H2AC20 | 3275.0 |
| SPI1 | 3112.0 |
| YAP1 | 3070.0 |
| PSMB4 | 3049.0 |
| PSMC1 | 2987.0 |
| H3C2 | 2976.0 |
| H2BC11 | 2506.0 |
| MNAT1 | 2449.0 |
| PSMA8 | 2379.0 |
| PSMD1 | 2144.0 |
| PSME4 | 2128.0 |
| PSMB5 | 2078.0 |
| PSMC3 | 1749.0 |
| H2BC21 | 1717.0 |
| SEM1 | 1657.0 |
| PSMC2 | 1653.0 |
| PSMD4 | 1403.0 |
| CDK7 | 909.0 |
| H2AX | 764.0 |
| PSMA5 | 665.0 |
| H3C11 | 608.0 |
| ABL1 | 607.0 |
| PSMA2 | 467.0 |
| PSMD3 | 274.0 |
| H4C1 | -64.0 |
| H3C6 | -174.0 |
| PSMD14 | -192.0 |
| TCF12 | -294.0 |
| PSME3 | -576.0 |
| H2BC10 | -630.0 |
| PSME1 | -840.0 |
| H3C8 | -1062.0 |
| PSMD6 | -1076.0 |
| PSMD11 | -1095.0 |
| H4C13 | -1134.0 |
| PSMD5 | -1600.0 |
| H3-3B | -1628.0 |
| PSMD8 | -1715.0 |
| CBFB | -1862.0 |
| PSMD9 | -1897.0 |
| H4C12 | -1933.0 |
| H3C1 | -2029.0 |
| LMO1 | -3313.0 |
| H2BC13 | -3416.0 |
| TP73 | -3862.0 |
| PSMF1 | -4178.0 |
| H3C4 | -4187.0 |
| H2AC7 | -4211.0 |
| H2BC7 | -4211.0 |
| H2AC8 | -4264.0 |
| TAL1 | -4896.0 |
| H2BC8 | -5026.0 |
| PSMB6 | -5356.0 |
| RUNX1 | -5564.0 |
| PSMD2 | -6144.0 |
| H2BC26 | -7437.0 |
| H2BC1 | -8099.0 |
| H3C10 | -8558.0 |
| GATA3 | -8907.0 |
| H4C11 | -9168.0 |
| TCF3 | -10233.0 |
| PSMB11 | -10657.0 |
REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS
| 179 | |
|---|---|
| set | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS |
| setSize | 111 |
| pANOVA | 5.62e-07 |
| s.dist | 0.275 |
| p.adjustANOVA | 3.48e-05 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| NDUFAF1 | 10323 |
| UQCR10 | 10295 |
| COX6A1 | 9998 |
| NDUFA4 | 9820 |
| CYCS | 9761 |
| ATP5PD | 9731 |
| NDUFAF3 | 9509 |
| COX16 | 9398 |
| UQCRFS1 | 9198 |
| UQCRC2 | 9085 |
| NDUFB4 | 9028 |
| SCO1 | 8569 |
| NDUFA11 | 8364 |
| ATP5MC2 | 8325 |
| ATP5F1C | 8269 |
| NDUFA2 | 8235 |
| NDUFS1 | 8164 |
| NDUFB10 | 8152 |
| ATP5F1A | 8103 |
| NDUFB7 | 8041 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| NDUFAF1 | 10323 |
| UQCR10 | 10295 |
| COX6A1 | 9998 |
| NDUFA4 | 9820 |
| CYCS | 9761 |
| ATP5PD | 9731 |
| NDUFAF3 | 9509 |
| COX16 | 9398 |
| UQCRFS1 | 9198 |
| UQCRC2 | 9085 |
| NDUFB4 | 9028 |
| SCO1 | 8569 |
| NDUFA11 | 8364 |
| ATP5MC2 | 8325 |
| ATP5F1C | 8269 |
| NDUFA2 | 8235 |
| NDUFS1 | 8164 |
| NDUFB10 | 8152 |
| ATP5F1A | 8103 |
| NDUFB7 | 8041 |
| COQ10B | 7914 |
| COX11 | 7898 |
| NDUFB1 | 7742 |
| COX5A | 7405 |
| UQCRQ | 7364 |
| TACO1 | 7132 |
| COX6B1 | 7125 |
| NDUFA6 | 6975 |
| UQCR11 | 6736 |
| ATP5F1D | 6645 |
| ETFB | 6576 |
| NDUFAF5 | 6407 |
| ECSIT | 6281 |
| NDUFC2 | 6200 |
| COX7A2L | 6108 |
| ATP5ME | 5869 |
| SLC25A27 | 5866 |
| NDUFB3 | 5772 |
| SCO2 | 5680 |
| UQCRB | 5427 |
| NDUFB8 | 5384 |
| COX6C | 5172 |
| ATP5F1B | 5042 |
| NDUFS4 | 5019 |
| ATP5PB | 4992 |
| UCP1 | 4904 |
| COX4I1 | 4877 |
| NDUFV2 | 4783 |
| SDHD | 4692 |
| NDUFA9 | 4690 |
| UQCRH | 4592 |
| NDUFB6 | 4466 |
| ATP5MG | 4387 |
| NDUFS3 | 4328 |
| ATP5MC3 | 4279 |
| ATP5F1E | 4150 |
| ETFDH | 3842 |
| NDUFC1 | 3838 |
| ATP5PO | 3692 |
| NDUFB5 | 3438 |
| NDUFAF2 | 3096 |
| NDUFAB1 | 2668 |
| COX18 | 2659 |
| COA1 | 2564 |
| NDUFAF7 | 2432 |
| COX20 | 2082 |
| NDUFAF6 | 1769 |
| NDUFAF4 | 1704 |
| NDUFA12 | 1676 |
| NDUFA7 | 1656 |
| SDHB | 1523 |
| NDUFA8 | 1513 |
| TIMMDC1 | 1035 |
| CYC1 | 733 |
| SDHC | 684 |
| COX5B | 536 |
| COX8A | 395 |
| NDUFS5 | 348 |
| COX19 | 256 |
| ETFA | 59 |
| TMEM126B | -52 |
| NDUFA5 | -561 |
| UCP2 | -670 |
| NDUFB2 | -679 |
| ATP5MC1 | -686 |
| DMAC2L | -867 |
| COQ10A | -872 |
| COX14 | -1067 |
| ATP5MF | -1269 |
| UQCRC1 | -1467 |
| TMEM186 | -1550 |
| ATP5PF | -1740 |
| NUBPL | -2569 |
| SURF1 | -2649 |
| LRPPRC | -3867 |
| NDUFV3 | -3964 |
| NDUFB9 | -4631 |
| NDUFS2 | -5197 |
| NDUFA13 | -5522 |
| PM20D1 | -5605 |
| NDUFS8 | -5793 |
| NDUFA3 | -5868 |
| UCP3 | -5875 |
| NDUFV1 | -6983 |
| COX7C | -7158 |
| SDHA | -7709 |
| NDUFS6 | -7949 |
| NDUFA10 | -8431 |
| NDUFS7 | -8507 |
| TRAP1 | -9528 |
| ACAD9 | -9685 |
REACTOME_RNA_POLYMERASE_I_PROMOTER_ESCAPE
| 1157 | |
|---|---|
| set | REACTOME_RNA_POLYMERASE_I_PROMOTER_ESCAPE |
| setSize | 83 |
| pANOVA | 5.72e-07 |
| s.dist | 0.317 |
| p.adjustANOVA | 3.48e-05 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| H3C12 | 10132 |
| POLR1G | 10100 |
| TBP | 9764 |
| GTF2H3 | 9734 |
| TAF1A | 9594 |
| H2BC14 | 9436 |
| H4C8 | 9408 |
| H2AC14 | 9305 |
| H2BC17 | 9247 |
| H3-3A | 9239 |
| POLR1H | 9171 |
| H3C3 | 9111 |
| POLR1C | 9086 |
| H2AZ1 | 8894 |
| POLR2L | 8803 |
| H2BC5 | 8646 |
| H4C4 | 8378 |
| RRN3 | 8163 |
| H2BC4 | 7968 |
| POLR1E | 7847 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| H3C12 | 10132.0 |
| POLR1G | 10100.0 |
| TBP | 9764.0 |
| GTF2H3 | 9734.0 |
| TAF1A | 9594.0 |
| H2BC14 | 9436.0 |
| H4C8 | 9408.0 |
| H2AC14 | 9305.0 |
| H2BC17 | 9247.0 |
| H3-3A | 9239.0 |
| POLR1H | 9171.0 |
| H3C3 | 9111.0 |
| POLR1C | 9086.0 |
| H2AZ1 | 8894.0 |
| POLR2L | 8803.0 |
| H2BC5 | 8646.0 |
| H4C4 | 8378.0 |
| RRN3 | 8163.0 |
| H2BC4 | 7968.0 |
| POLR1E | 7847.0 |
| POLR2H | 7324.0 |
| H2AC18 | 7261.5 |
| H2AC19 | 7261.5 |
| H2AC6 | 7006.0 |
| H2BC15 | 6756.0 |
| H4C3 | 6755.0 |
| H2BC9 | 6696.5 |
| H3C7 | 6696.5 |
| H2AC4 | 6574.0 |
| H2AZ2 | 6477.0 |
| H4C5 | 6455.0 |
| CBX3 | 6445.0 |
| POLR2E | 6038.0 |
| TAF1D | 5907.0 |
| CCNH | 5625.0 |
| POLR2K | 5369.0 |
| POLR1B | 5276.0 |
| H2BC3 | 5022.0 |
| H4C9 | 4853.0 |
| H4C16 | 4688.0 |
| H2AJ | 4666.0 |
| H2BC6 | 4552.0 |
| H4C2 | 4300.0 |
| H4C6 | 4018.0 |
| POLR1D | 3965.0 |
| H2BC12 | 3661.0 |
| GTF2H4 | 3554.0 |
| H2AC20 | 3275.0 |
| H3C2 | 2976.0 |
| GTF2H5 | 2954.0 |
| POLR1F | 2809.0 |
| H2BC11 | 2506.0 |
| MNAT1 | 2449.0 |
| GTF2H1 | 2440.0 |
| H2BC21 | 1717.0 |
| TAF1B | 1327.0 |
| CDK7 | 909.0 |
| H2AX | 764.0 |
| H3C11 | 608.0 |
| H4C1 | -64.0 |
| POLR1A | -88.0 |
| H3C6 | -174.0 |
| H2BC10 | -630.0 |
| UBTF | -1032.0 |
| H3C8 | -1062.0 |
| H4C13 | -1134.0 |
| ERCC3 | -1589.0 |
| H3-3B | -1628.0 |
| H4C12 | -1933.0 |
| H3C1 | -2029.0 |
| H2BC13 | -3416.0 |
| H3C4 | -4187.0 |
| H2AC7 | -4211.0 |
| H2BC7 | -4211.0 |
| H2AC8 | -4264.0 |
| H2BC8 | -5026.0 |
| POLR2F | -5251.0 |
| H2BC26 | -7437.0 |
| H2BC1 | -8099.0 |
| ERCC2 | -8106.0 |
| H3C10 | -8558.0 |
| H4C11 | -9168.0 |
| TAF1C | -9938.0 |
REACTOME_THE_CITRIC_ACID_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT
| 104 | |
|---|---|
| set | REACTOME_THE_CITRIC_ACID_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT |
| setSize | 159 |
| pANOVA | 7.02e-07 |
| s.dist | 0.228 |
| p.adjustANOVA | 4.12e-05 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| NDUFAF1 | 10323 |
| UQCR10 | 10295 |
| COX6A1 | 9998 |
| NDUFA4 | 9820 |
| CYCS | 9761 |
| ATP5PD | 9731 |
| NDUFAF3 | 9509 |
| COX16 | 9398 |
| UQCRFS1 | 9198 |
| CS | 9092 |
| UQCRC2 | 9085 |
| SUCLA2 | 9051 |
| NDUFB4 | 9028 |
| SCO1 | 8569 |
| LDHA | 8493 |
| NDUFA11 | 8364 |
| ATP5MC2 | 8325 |
| ATP5F1C | 8269 |
| NDUFA2 | 8235 |
| FAHD1 | 8215 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| NDUFAF1 | 10323 |
| UQCR10 | 10295 |
| COX6A1 | 9998 |
| NDUFA4 | 9820 |
| CYCS | 9761 |
| ATP5PD | 9731 |
| NDUFAF3 | 9509 |
| COX16 | 9398 |
| UQCRFS1 | 9198 |
| CS | 9092 |
| UQCRC2 | 9085 |
| SUCLA2 | 9051 |
| NDUFB4 | 9028 |
| SCO1 | 8569 |
| LDHA | 8493 |
| NDUFA11 | 8364 |
| ATP5MC2 | 8325 |
| ATP5F1C | 8269 |
| NDUFA2 | 8235 |
| FAHD1 | 8215 |
| DLD | 8214 |
| NDUFS1 | 8164 |
| NDUFB10 | 8152 |
| ATP5F1A | 8103 |
| NDUFB7 | 8041 |
| IDH3B | 8036 |
| DLST | 8002 |
| PDPR | 7921 |
| COQ10B | 7914 |
| COX11 | 7898 |
| NDUFB1 | 7742 |
| LDHB | 7574 |
| IDH2 | 7484 |
| COX5A | 7405 |
| UQCRQ | 7364 |
| TACO1 | 7132 |
| COX6B1 | 7125 |
| MPC2 | 7109 |
| NDUFA6 | 6975 |
| UQCR11 | 6736 |
| ATP5F1D | 6645 |
| ETFB | 6576 |
| PDP1 | 6522 |
| MPC1 | 6416 |
| NDUFAF5 | 6407 |
| SLC16A1 | 6349 |
| ECSIT | 6281 |
| NDUFC2 | 6200 |
| GLO1 | 6114 |
| COX7A2L | 6108 |
| ATP5ME | 5869 |
| SLC25A27 | 5866 |
| NDUFB3 | 5772 |
| SCO2 | 5680 |
| UQCRB | 5427 |
| NDUFB8 | 5384 |
| PDP2 | 5325 |
| COX6C | 5172 |
| ATP5F1B | 5042 |
| NDUFS4 | 5019 |
| ATP5PB | 4992 |
| UCP1 | 4904 |
| COX4I1 | 4877 |
| PDK1 | 4796 |
| NDUFV2 | 4783 |
| SDHD | 4692 |
| NDUFA9 | 4690 |
| UQCRH | 4592 |
| DLAT | 4567 |
| NDUFB6 | 4466 |
| ATP5MG | 4387 |
| PDHB | 4345 |
| NDUFS3 | 4328 |
| ATP5MC3 | 4279 |
| FH | 4200 |
| LDHC | 4167 |
| ATP5F1E | 4150 |
| NNT | 4135 |
| LDHAL6A | 4083 |
| ETFDH | 3842 |
| NDUFC1 | 3838 |
| ATP5PO | 3692 |
| BSG | 3484 |
| NDUFB5 | 3438 |
| NDUFAF2 | 3096 |
| NDUFAB1 | 2668 |
| COX18 | 2659 |
| COA1 | 2564 |
| NDUFAF7 | 2432 |
| COX20 | 2082 |
| ME1 | 1888 |
| NDUFAF6 | 1769 |
| NDUFAF4 | 1704 |
| NDUFA12 | 1676 |
| NDUFA7 | 1656 |
| SDHB | 1523 |
| NDUFA8 | 1513 |
| TIMMDC1 | 1035 |
| OGDH | 923 |
| CYC1 | 733 |
| SDHC | 684 |
| COX5B | 536 |
| COX8A | 395 |
| NDUFS5 | 348 |
| COX19 | 256 |
| MDH2 | 213 |
| ETFA | 59 |
| TMEM126B | -52 |
| L2HGDH | -417 |
| PDK4 | -443 |
| NDUFA5 | -561 |
| UCP2 | -670 |
| NDUFB2 | -679 |
| ATP5MC1 | -686 |
| DMAC2L | -867 |
| COQ10A | -872 |
| COX14 | -1067 |
| IDH3A | -1197 |
| ATP5MF | -1269 |
| UQCRC1 | -1467 |
| TMEM186 | -1550 |
| ATP5PF | -1740 |
| SUCLG1 | -2031 |
| PDHX | -2106 |
| SUCLG2 | -2422 |
| ME2 | -2512 |
| NUBPL | -2569 |
| SURF1 | -2649 |
| PDHA2 | -3678 |
| LRPPRC | -3867 |
| NDUFV3 | -3964 |
| VDAC1 | -4105 |
| NDUFB9 | -4631 |
| GSTZ1 | -4759 |
| NDUFS2 | -5197 |
| HAGH | -5246 |
| ADHFE1 | -5435 |
| NDUFA13 | -5522 |
| PM20D1 | -5605 |
| NDUFS8 | -5793 |
| NDUFA3 | -5868 |
| UCP3 | -5875 |
| ME3 | -6231 |
| SLC16A8 | -6848 |
| PPARD | -6978 |
| NDUFV1 | -6983 |
| COX7C | -7158 |
| PDK2 | -7219 |
| SDHA | -7709 |
| NDUFS6 | -7949 |
| ACO2 | -8308 |
| NDUFA10 | -8431 |
| NDUFS7 | -8507 |
| D2HGDH | -8545 |
| RXRA | -9025 |
| SLC16A3 | -9329 |
| TRAP1 | -9528 |
| ACAD9 | -9685 |
| LDHAL6B | -10784 |
REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA
| 1146 | |
|---|---|
| set | REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA |
| setSize | 263 |
| pANOVA | 7.31e-07 |
| s.dist | 0.177 |
| p.adjustANOVA | 4.14e-05 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| ZMAT2 | 10215 |
| PRPF19 | 10124 |
| FAM32A | 9973 |
| SRSF1 | 9784 |
| SNRPF | 9718 |
| HNRNPL | 9450 |
| PRKRIP1 | 9431 |
| SRSF10 | 9381 |
| TPR | 9369 |
| NUP35 | 9338 |
| NXT1 | 9315 |
| NUP107 | 9241 |
| PCBP1 | 9188 |
| RBM8A | 9093 |
| POLR2L | 8803 |
| CRNKL1 | 8786 |
| NUP43 | 8731 |
| ISY1 | 8721 |
| LENG1 | 8714 |
| PRPF38A | 8667 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ZMAT2 | 10215 |
| PRPF19 | 10124 |
| FAM32A | 9973 |
| SRSF1 | 9784 |
| SNRPF | 9718 |
| HNRNPL | 9450 |
| PRKRIP1 | 9431 |
| SRSF10 | 9381 |
| TPR | 9369 |
| NUP35 | 9338 |
| NXT1 | 9315 |
| NUP107 | 9241 |
| PCBP1 | 9188 |
| RBM8A | 9093 |
| POLR2L | 8803 |
| CRNKL1 | 8786 |
| NUP43 | 8731 |
| ISY1 | 8721 |
| LENG1 | 8714 |
| PRPF38A | 8667 |
| LUC7L3 | 8627 |
| POLR2D | 8521 |
| POLR2C | 8482 |
| PCBP2 | 8264 |
| CSTF2T | 8207 |
| SRSF6 | 8166 |
| NUP153 | 8165 |
| SNRPD2 | 8144 |
| CDC40 | 8132 |
| PPIH | 8060 |
| THOC1 | 7863 |
| PPIG | 7844 |
| HSPA8 | 7776 |
| CLP1 | 7758 |
| SNRPD3 | 7673 |
| POLR2I | 7672 |
| NUP155 | 7642 |
| SNRNP25 | 7507 |
| SARNP | 7472 |
| LSM6 | 7450 |
| UBL5 | 7408 |
| GCFC2 | 7366 |
| PAPOLA | 7352 |
| ZCRB1 | 7346 |
| CWC15 | 7329 |
| POLR2H | 7324 |
| U2SURP | 7274 |
| SYMPK | 7264 |
| RBM22 | 7220 |
| WBP11 | 7210 |
| SNRPA | 6969 |
| IK | 6968 |
| HNRNPA1 | 6967 |
| THOC6 | 6907 |
| PTBP1 | 6857 |
| PPIL1 | 6856 |
| LSM5 | 6808 |
| HNRNPA2B1 | 6790 |
| HNRNPF | 6777 |
| PPIL3 | 6738 |
| FYTTD1 | 6681 |
| SNW1 | 6642 |
| MFAP1 | 6580 |
| LSM4 | 6570 |
| PRPF40A | 6288 |
| CWC22 | 6219 |
| POLR2E | 6038 |
| HNRNPD | 6019 |
| CSTF1 | 6015 |
| SNRNP27 | 5885 |
| PCF11 | 5722 |
| NUP54 | 5663 |
| CPSF2 | 5646 |
| SF3A2 | 5538 |
| NUP50 | 5527 |
| WTAP | 5485 |
| METTL14 | 5456 |
| PHF5A | 5381 |
| POLR2K | 5369 |
| SNRNP35 | 5272 |
| PRPF4 | 5243 |
| HNRNPR | 5086 |
| EIF4E | 4924 |
| NXF1 | 4820 |
| DDX39A | 4808 |
| DHX9 | 4760 |
| PDCD7 | 4704 |
| NCBP1 | 4593 |
| USP39 | 4454 |
| PPWD1 | 4404 |
| POM121 | 4393 |
| PRCC | 4383 |
| RBM7 | 4367 |
| THOC5 | 4309 |
| CWC27 | 4280 |
| PNN | 4274 |
| SRSF2 | 4105 |
| BUD31 | 4041 |
| WBP4 | 4019 |
| SMNDC1 | 3925 |
| SF3A3 | 3848 |
| POM121C | 3776 |
| SYF2 | 3763 |
| SRSF3 | 3757 |
| CPSF6 | 3738 |
| C9orf78 | 3702 |
| RBM17 | 3546 |
| SF3B5 | 3485 |
| NUP133 | 3422 |
| RBM39 | 3399 |
| CPSF3 | 3298 |
| SF3B1 | 3294 |
| HNRNPU | 3260 |
| DHX8 | 3228 |
| NUP205 | 3185 |
| POLDIP3 | 3152 |
| LSM7 | 3122 |
| SNRPB2 | 3100 |
| CDC5L | 3089 |
| MTREX | 2997 |
| SNRPA1 | 2983 |
| GPATCH1 | 2966 |
| WDR33 | 2922 |
| ZNF830 | 2871 |
| TRA2B | 2818 |
| ALYREF | 2764 |
| U2AF1L4 | 2692 |
| ZMAT5 | 2645 |
| NUDT21 | 2618 |
| HNRNPA3 | 2549 |
| SRSF11 | 2478 |
| BUD13 | 2428 |
| SNRPN | 2421 |
| NDC1 | 2410 |
| NSRP1 | 2385 |
| CWC25 | 2378 |
| ACIN1 | 2310 |
| CSTF3 | 2236 |
| CCDC12 | 2213 |
| POLR2G | 2138 |
| SRRM1 | 2110 |
| HNRNPH1 | 2042 |
| SDE2 | 2032 |
| SLBP | 1943 |
| PRPF6 | 1851 |
| MAGOH | 1757 |
| DDX46 | 1735 |
| CCAR1 | 1712 |
| SRSF7 | 1680 |
| DDX5 | 1661 |
| HNRNPM | 1584 |
| SNRNP70 | 1557 |
| NCBP2 | 1556 |
| CASC3 | 1522 |
| EFTUD2 | 1479 |
| TXNL4A | 1452 |
| BCAS2 | 1451 |
| SNRNP48 | 1448 |
| NUP88 | 1277 |
| RAE1 | 1215 |
| RANBP2 | 1191 |
| HNRNPC | 1166 |
| SF3B3 | 1141 |
| RNPS1 | 1122 |
| SNRPE | 1062 |
| METTL3 | 866 |
| DHX35 | 820 |
| SRSF8 | 703 |
| PLRG1 | 664 |
| NUP160 | 618 |
| DDX23 | 412 |
| FUS | 375 |
| NUP98 | 368 |
| SNIP1 | 182 |
| LSM3 | 93 |
| ZC3H11A | 85 |
| SRSF5 | 65 |
| YBX1 | 28 |
| SF3A1 | 15 |
| SNRNP40 | -4 |
| CWF19L2 | -145 |
| RNPC3 | -184 |
| AQR | -674 |
| HNRNPK | -680 |
| SEH1L | -682 |
| MAGOHB | -712 |
| DNAJC8 | -868 |
| PRPF31 | -965 |
| SF3B2 | -1084 |
| SF3B4 | -1087 |
| NUP42 | -1128 |
| LSM2 | -1401 |
| LSM8 | -1515 |
| RBM42 | -1555 |
| NUP37 | -1790 |
| GTF2F1 | -1794 |
| PPIL4 | -1912 |
| DDX39B | -2196 |
| PPP1R8 | -2264 |
| SEC13 | -2354 |
| GTF2F2 | -2395 |
| SAP18 | -2669 |
| RBM25 | -3073 |
| PRPF18 | -3131 |
| POLR2B | -3675 |
| PRPF8 | -3832 |
| SNRPG | -3880 |
| DHX16 | -4101 |
| DDX42 | -4112 |
| SF1 | -4165 |
| SMU1 | -4169 |
| SNU13 | -4219 |
| FIP1L1 | -4270 |
| PABPN1 | -4462 |
| NUP214 | -4467 |
| SNRPC | -4491 |
| XAB2 | -4792 |
| SRSF4 | -4901 |
| GLE1 | -4935 |
| TCERG1 | -4997 |
| DHX38 | -5092 |
| NUP93 | -5201 |
| POLR2F | -5251 |
| TFIP11 | -5351 |
| CTNNBL1 | -5418 |
| THOC3 | -5567 |
| SF3B6 | -5635 |
| CACTIN | -5757 |
| THOC7 | -5923 |
| NUP62 | -6129 |
| SLU7 | -6202 |
| CHTOP | -6317 |
| DHX15 | -6401 |
| SNRPB | -6416 |
| CPSF7 | -6485 |
| WDR70 | -6498 |
| RBM5 | -6661 |
| YJU2 | -6684 |
| SNRPD1 | -6773 |
| SRSF12 | -6877 |
| CPSF4 | -7119 |
| NUP188 | -7120 |
| SUGP1 | -7162 |
| U2AF2 | -7309 |
| CPSF1 | -7597 |
| PUF60 | -7700 |
| NUP58 | -7794 |
| PPIL2 | -7929 |
| SRRT | -8192 |
| POLR2A | -8208 |
| NUP85 | -8221 |
| PPIE | -8228 |
| AAAS | -8286 |
| SRSF9 | -8494 |
| NUP210 | -8505 |
| PRPF3 | -8612 |
| EIF4A3 | -8763 |
| SRRM2 | -9273 |
| SNRNP200 | -9564 |
| SART1 | -9944 |
| CHERP | -10004 |
| DDX41 | -10063 |
| POLR2J | -10901 |
REACTOME_G2_M_CHECKPOINTS
| 1116 | |
|---|---|
| set | REACTOME_G2_M_CHECKPOINTS |
| setSize | 162 |
| pANOVA | 7.68e-07 |
| s.dist | 0.225 |
| p.adjustANOVA | 4.2e-05 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| UBB | 10269 |
| CLSPN | 10217 |
| RFC4 | 9786 |
| RPA2 | 9599 |
| H2BC14 | 9436 |
| H4C8 | 9408 |
| RAD1 | 9403 |
| KAT5 | 9291 |
| PSMB3 | 9282 |
| H2BC17 | 9247 |
| PSMA6 | 9088 |
| PSMA7 | 8947 |
| CHEK2 | 8765 |
| PSME2 | 8738 |
| PSMC5 | 8695 |
| UBC | 8680 |
| PSMA1 | 8676 |
| H2BC5 | 8646 |
| YWHAH | 8406 |
| H4C4 | 8378 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| UBB | 10269.0 |
| CLSPN | 10217.0 |
| RFC4 | 9786.0 |
| RPA2 | 9599.0 |
| H2BC14 | 9436.0 |
| H4C8 | 9408.0 |
| RAD1 | 9403.0 |
| KAT5 | 9291.0 |
| PSMB3 | 9282.0 |
| H2BC17 | 9247.0 |
| PSMA6 | 9088.0 |
| PSMA7 | 8947.0 |
| CHEK2 | 8765.0 |
| PSME2 | 8738.0 |
| PSMC5 | 8695.0 |
| UBC | 8680.0 |
| PSMA1 | 8676.0 |
| H2BC5 | 8646.0 |
| YWHAH | 8406.0 |
| H4C4 | 8378.0 |
| PSMD12 | 8377.0 |
| MCM5 | 8203.0 |
| PSMB1 | 8157.0 |
| PSMC4 | 8042.0 |
| H2BC4 | 7968.0 |
| MCM2 | 7892.0 |
| CDK1 | 7556.0 |
| ORC6 | 7475.0 |
| DBF4 | 7327.0 |
| PSMB9 | 7201.0 |
| RAD17 | 7183.0 |
| ORC1 | 7122.0 |
| UBA52 | 6901.0 |
| WEE1 | 6804.0 |
| H2BC15 | 6756.0 |
| H4C3 | 6755.0 |
| H2BC9 | 6696.5 |
| H4C5 | 6455.0 |
| PSMB7 | 6283.0 |
| RPS27A | 6223.0 |
| PSMB10 | 6211.0 |
| CDC25C | 6173.0 |
| BABAM1 | 6143.0 |
| CDK2 | 6121.0 |
| YWHAZ | 6039.0 |
| PSMB8 | 6003.0 |
| RBBP8 | 5966.0 |
| PSMD13 | 5916.0 |
| EXO1 | 5642.0 |
| CDC6 | 5425.0 |
| PSMC6 | 5420.0 |
| BRCA1 | 5239.0 |
| RPA3 | 5112.0 |
| H2BC3 | 5022.0 |
| PSMA4 | 4963.0 |
| PSMD7 | 4932.0 |
| CCNB1 | 4895.0 |
| H4C9 | 4853.0 |
| H4C16 | 4688.0 |
| MRE11 | 4573.0 |
| H2BC6 | 4552.0 |
| H4C2 | 4300.0 |
| ABRAXAS1 | 4179.0 |
| PSMA3 | 4116.0 |
| H4C6 | 4018.0 |
| RHNO1 | 3991.0 |
| H2BC12 | 3661.0 |
| RFC2 | 3550.0 |
| ATM | 3539.0 |
| UBE2N | 3457.0 |
| PSMB2 | 3326.0 |
| MDC1 | 3251.0 |
| ATR | 3230.0 |
| PSMB4 | 3049.0 |
| PSMC1 | 2987.0 |
| WRN | 2771.0 |
| MCM3 | 2768.0 |
| YWHAG | 2674.0 |
| RAD9B | 2575.0 |
| H2BC11 | 2506.0 |
| YWHAE | 2415.0 |
| BLM | 2402.0 |
| PSMA8 | 2379.0 |
| UIMC1 | 2348.0 |
| TOP3A | 2260.0 |
| RNF8 | 2201.0 |
| PSMD1 | 2144.0 |
| PSME4 | 2128.0 |
| PSMB5 | 2078.0 |
| CCNB2 | 1987.0 |
| RMI2 | 1950.0 |
| PSMC3 | 1749.0 |
| H2BC21 | 1717.0 |
| ORC2 | 1682.0 |
| SEM1 | 1657.0 |
| PSMC2 | 1653.0 |
| BRIP1 | 1521.0 |
| CDC45 | 1460.0 |
| PSMD4 | 1403.0 |
| ORC3 | 1332.0 |
| ORC4 | 1301.0 |
| TP53 | 830.0 |
| TP53BP1 | 817.0 |
| RAD50 | 807.0 |
| RFC5 | 799.0 |
| H2AX | 764.0 |
| PSMA5 | 665.0 |
| PSMA2 | 467.0 |
| RFC3 | 297.0 |
| PSMD3 | 274.0 |
| H4C1 | -64.0 |
| RPA1 | -66.0 |
| PSMD14 | -192.0 |
| MCM8 | -373.0 |
| ORC5 | -485.0 |
| PSME3 | -576.0 |
| H2BC10 | -630.0 |
| PSME1 | -840.0 |
| CHEK1 | -886.0 |
| PSMD6 | -1076.0 |
| YWHAQ | -1078.0 |
| PSMD11 | -1095.0 |
| H4C13 | -1134.0 |
| MCM4 | -1157.0 |
| PKMYT1 | -1216.0 |
| PSMD5 | -1600.0 |
| YWHAB | -1708.0 |
| PSMD8 | -1715.0 |
| CDC7 | -1848.0 |
| PSMD9 | -1897.0 |
| H4C12 | -1933.0 |
| GTSE1 | -2249.0 |
| RMI1 | -2292.0 |
| HUS1 | -2809.0 |
| BABAM2 | -2816.0 |
| TOPBP1 | -3051.0 |
| H2BC13 | -3416.0 |
| RNF168 | -3445.0 |
| UBE2V2 | -4004.0 |
| PSMF1 | -4178.0 |
| H2BC7 | -4211.0 |
| DNA2 | -4453.0 |
| H3-4 | -4629.0 |
| MCM7 | -4806.0 |
| NBN | -4811.0 |
| H2BC8 | -5026.0 |
| RAD9A | -5227.0 |
| PSMB6 | -5356.0 |
| PIAS4 | -5616.0 |
| MCM6 | -5942.0 |
| BARD1 | -6121.0 |
| PSMD2 | -6144.0 |
| NSD2 | -6514.0 |
| MCM10 | -6748.0 |
| H2BC26 | -7437.0 |
| CDC25A | -7551.0 |
| H2BC1 | -8099.0 |
| SFN | -8815.0 |
| H4C11 | -9168.0 |
| ATRIP | -9533.0 |
| HERC2 | -9902.0 |
| PSMB11 | -10657.0 |
REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY
| 1591 | |
|---|---|
| set | REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY |
| setSize | 33 |
| pANOVA | 1.33e-06 |
| s.dist | 0.486 |
| p.adjustANOVA | 7.06e-05 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS12 | 10065 |
| RPSA | 9598 |
| EEF1A1 | 9508 |
| RPS18 | 8418 |
| RPS14 | 8367 |
| RPS28 | 8053 |
| RPS10 | 7422 |
| RPS9 | 7239 |
| HNRNPA1 | 6967 |
| RPS13 | 6745 |
| RPS21 | 6312 |
| RPS27A | 6223 |
| RPS23 | 6171 |
| RPS2 | 6145 |
| RPS3A | 5876 |
| RPS27L | 5650 |
| RPS16 | 5552 |
| FAU | 5376 |
| RPS11 | 4468 |
| RPS20 | 4174 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS12 | 10065 |
| RPSA | 9598 |
| EEF1A1 | 9508 |
| RPS18 | 8418 |
| RPS14 | 8367 |
| RPS28 | 8053 |
| RPS10 | 7422 |
| RPS9 | 7239 |
| HNRNPA1 | 6967 |
| RPS13 | 6745 |
| RPS21 | 6312 |
| RPS27A | 6223 |
| RPS23 | 6171 |
| RPS2 | 6145 |
| RPS3A | 5876 |
| RPS27L | 5650 |
| RPS16 | 5552 |
| FAU | 5376 |
| RPS11 | 4468 |
| RPS20 | 4174 |
| RPS15A | 4169 |
| RPS8 | 4117 |
| RPS19 | 3558 |
| RPS5 | 3408 |
| RPS24 | 3357 |
| RPS7 | 3333 |
| RPS29 | 2812 |
| RPS26 | 2583 |
| RPS27 | 2232 |
| RPS25 | 2059 |
| RPS6 | 1237 |
| RPS3 | -935 |
| RPS15 | -2768 |
REACTOME_CHROMOSOME_MAINTENANCE
| 1165 | |
|---|---|
| set | REACTOME_CHROMOSOME_MAINTENANCE |
| setSize | 130 |
| pANOVA | 1.46e-06 |
| s.dist | 0.245 |
| p.adjustANOVA | 7.51e-05 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| GAR1 | 9822 |
| RFC4 | 9786 |
| PPP6C | 9625 |
| RPA2 | 9599 |
| H2BC14 | 9436 |
| TINF2 | 9413 |
| H4C8 | 9408 |
| H2AC14 | 9305 |
| OIP5 | 9269 |
| H2BC17 | 9247 |
| H3-3A | 9239 |
| DSCC1 | 9163 |
| H2AZ1 | 8894 |
| POLR2L | 8803 |
| CENPM | 8748 |
| H2BC5 | 8646 |
| POLR2D | 8521 |
| POLR2C | 8482 |
| H4C4 | 8378 |
| TEN1 | 8346 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| GAR1 | 9822.0 |
| RFC4 | 9786.0 |
| PPP6C | 9625.0 |
| RPA2 | 9599.0 |
| H2BC14 | 9436.0 |
| TINF2 | 9413.0 |
| H4C8 | 9408.0 |
| H2AC14 | 9305.0 |
| OIP5 | 9269.0 |
| H2BC17 | 9247.0 |
| H3-3A | 9239.0 |
| DSCC1 | 9163.0 |
| H2AZ1 | 8894.0 |
| POLR2L | 8803.0 |
| CENPM | 8748.0 |
| H2BC5 | 8646.0 |
| POLR2D | 8521.0 |
| POLR2C | 8482.0 |
| H4C4 | 8378.0 |
| TEN1 | 8346.0 |
| CENPL | 8278.0 |
| FEN1 | 7987.0 |
| H2BC4 | 7968.0 |
| TERF2IP | 7705.0 |
| PCNA | 7690.0 |
| POLR2I | 7672.0 |
| CENPC | 7622.0 |
| MIS18BP1 | 7336.0 |
| POLR2H | 7324.0 |
| MIS18A | 7268.0 |
| H2AC18 | 7261.5 |
| H2AC19 | 7261.5 |
| CTC1 | 7149.0 |
| POLD4 | 7077.0 |
| H2AC6 | 7006.0 |
| CENPA | 6757.0 |
| H2BC15 | 6756.0 |
| H4C3 | 6755.0 |
| H2BC9 | 6696.5 |
| H2AC4 | 6574.0 |
| H2AZ2 | 6477.0 |
| H4C5 | 6455.0 |
| CDK2 | 6121.0 |
| ITGB3BP | 6053.0 |
| POLR2E | 6038.0 |
| RUVBL2 | 5924.0 |
| DAXX | 5912.0 |
| RBBP4 | 5906.0 |
| POLR2K | 5369.0 |
| RPA3 | 5112.0 |
| H2BC3 | 5022.0 |
| H4C9 | 4853.0 |
| H4C16 | 4688.0 |
| CENPH | 4681.0 |
| H2AJ | 4666.0 |
| H2BC6 | 4552.0 |
| POLA2 | 4368.0 |
| H4C2 | 4300.0 |
| H4C6 | 4018.0 |
| H2BC12 | 3661.0 |
| RFC2 | 3550.0 |
| NPM1 | 3501.0 |
| CCNA1 | 3453.0 |
| STN1 | 3401.0 |
| TERF2 | 3331.0 |
| H2AC20 | 3275.0 |
| CENPQ | 3129.0 |
| SMARCA5 | 3044.0 |
| PRIM1 | 3021.0 |
| WRN | 2771.0 |
| ANKRD28 | 2712.0 |
| POT1 | 2588.0 |
| H2BC11 | 2506.0 |
| BLM | 2402.0 |
| SHQ1 | 2229.0 |
| POLR2G | 2138.0 |
| WRAP53 | 2126.0 |
| CENPK | 2007.0 |
| PRIM2 | 1823.0 |
| CENPT | 1722.0 |
| H2BC21 | 1717.0 |
| NOP10 | 1673.0 |
| RUVBL1 | 1408.0 |
| CENPN | 1269.0 |
| TERF1 | 948.0 |
| RFC5 | 799.0 |
| H2AX | 764.0 |
| CCNA2 | 521.0 |
| RFC3 | 297.0 |
| KNL1 | 199.0 |
| H4C1 | -64.0 |
| RPA1 | -66.0 |
| CENPS | -129.0 |
| H2BC10 | -630.0 |
| H4C13 | -1134.0 |
| PIF1 | -1489.0 |
| H3-3B | -1628.0 |
| CENPU | -1684.0 |
| H4C12 | -1933.0 |
| POLD3 | -1964.0 |
| NHP2 | -1967.0 |
| CENPO | -2939.0 |
| RFC1 | -2949.0 |
| H2BC13 | -3416.0 |
| CENPW | -3423.0 |
| CHTF8 | -3584.0 |
| POLR2B | -3675.0 |
| H2AC7 | -4211.0 |
| H2BC7 | -4211.0 |
| H2AC8 | -4264.0 |
| DNA2 | -4453.0 |
| H3-4 | -4629.0 |
| ACD | -4835.5 |
| H2BC8 | -5026.0 |
| POLR2F | -5251.0 |
| PPP6R3 | -5254.0 |
| RTEL1 | -5806.0 |
| CENPP | -5812.0 |
| RSF1 | -6213.0 |
| HJURP | -6835.0 |
| POLD1 | -6888.0 |
| H2BC26 | -7437.0 |
| CHTF18 | -7905.0 |
| TERT | -8080.0 |
| H2BC1 | -8099.0 |
| POLR2A | -8208.0 |
| POLD2 | -8372.0 |
| LIG1 | -9074.0 |
| H4C11 | -9168.0 |
| POLR2J | -10901.0 |
REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION
| 116 | |
|---|---|
| set | REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION |
| setSize | 291 |
| pANOVA | 1.51e-06 |
| s.dist | -0.164 |
| p.adjustANOVA | 7.52e-05 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CTRB2 | -10770 |
| LAMB3 | -10557 |
| EMILIN1 | -10402 |
| MMP14 | -10384 |
| CTRB1 | -10352 |
| CAPN9 | -10259 |
| CAPN3 | -10144 |
| ADAMTS4 | -10002 |
| FBN3 | -9951 |
| GDF5 | -9915 |
| SCUBE1 | -9914 |
| LTBP2 | -9906 |
| CAPN10 | -9854 |
| BMP1 | -9853 |
| CAPN11 | -9702 |
| COL9A2 | -9620 |
| COL5A1 | -9595 |
| COL6A2 | -9584 |
| CAPN15 | -9512 |
| ADAM8 | -9486 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CTRB2 | -10770 |
| LAMB3 | -10557 |
| EMILIN1 | -10402 |
| MMP14 | -10384 |
| CTRB1 | -10352 |
| CAPN9 | -10259 |
| CAPN3 | -10144 |
| ADAMTS4 | -10002 |
| FBN3 | -9951 |
| GDF5 | -9915 |
| SCUBE1 | -9914 |
| LTBP2 | -9906 |
| CAPN10 | -9854 |
| BMP1 | -9853 |
| CAPN11 | -9702 |
| COL9A2 | -9620 |
| COL5A1 | -9595 |
| COL6A2 | -9584 |
| CAPN15 | -9512 |
| ADAM8 | -9486 |
| LAMB2 | -9420 |
| CEACAM1 | -9409 |
| ITGB4 | -9406 |
| AGRN | -9394 |
| DMP1 | -9378 |
| CTSB | -9299 |
| COL13A1 | -9237 |
| P3H3 | -9187 |
| COL27A1 | -9158 |
| CAPN5 | -8968 |
| COL20A1 | -8950 |
| COL6A3 | -8926 |
| COL6A1 | -8837 |
| COL1A2 | -8686 |
| MATN1 | -8678 |
| LOXL1 | -8662 |
| PXDN | -8534 |
| HSPG2 | -8522 |
| COL11A2 | -8515 |
| FBLN1 | -8487 |
| LOXL2 | -8480 |
| PHYKPL | -8476 |
| ITGAD | -8426 |
| MMP15 | -8387 |
| ITGA7 | -8367 |
| LAMA5 | -8318 |
| NCSTN | -8170 |
| COL8A2 | -8113 |
| FBLN2 | -8102 |
| PLOD1 | -8091 |
| COL7A1 | -7886 |
| LTBP3 | -7880 |
| VTN | -7855 |
| ITGAX | -7789 |
| COL18A1 | -7739 |
| FURIN | -7705 |
| ITGA3 | -7653 |
| MMP24 | -7501 |
| MMP11 | -7494 |
| DAG1 | -7442 |
| MMP1 | -7436 |
| CD151 | -7409 |
| ITGA10 | -7405 |
| CTSD | -7379 |
| HTRA1 | -7350 |
| TMPRSS6 | -7235 |
| CAPN2 | -7233 |
| ACAN | -7164 |
| COL15A1 | -7141 |
| TNXB | -7126 |
| PLEC | -7106 |
| ADAMTS2 | -7061 |
| ITGB7 | -7030 |
| SDC4 | -6994 |
| SCUBE3 | -6898 |
| DSPP | -6868 |
| CAPN8 | -6799 |
| SERPINH1 | -6603 |
| PTPRS | -6566 |
| CAPNS2 | -6518 |
| ADAMTS14 | -6487 |
| ITGB2 | -6443 |
| ADAM15 | -6374 |
| ITGAM | -6304 |
| ASPN | -6280 |
| COL22A1 | -6272 |
| KLKB1 | -6252 |
| COL1A1 | -6090 |
| JAM3 | -5817 |
| VWF | -5784 |
| PCOLCE | -5715 |
| TNC | -5476 |
| CEACAM8 | -5455 |
| MMP25 | -5448 |
| COL2A1 | -5392 |
| ITGB5 | -5382 |
| ADAMTS3 | -5310 |
| TGFB3 | -5286 |
| MFAP5 | -5226 |
| THBS1 | -5216 |
| COL26A1 | -5199 |
| PDGFA | -5196 |
| BMP2 | -5186 |
| FN1 | -5178 |
| COL3A1 | -5126 |
| FGF2 | -5089 |
| SDC1 | -5052 |
| COLGALT1 | -4974 |
| FGA | -4954 |
| COLGALT2 | -4932 |
| ITGA2 | -4921 |
| SH3PXD2A | -4908 |
| LOXL4 | -4907 |
| SPARC | -4868 |
| MMP2 | -4819 |
| FGB | -4775 |
| MMP12 | -4597 |
| COL17A1 | -4525 |
| LAMB1 | -4447 |
| ADAM12 | -4442 |
| TGFB2 | -4406 |
| ITGAV | -4331 |
| P3H1 | -4284 |
| MMP17 | -4110 |
| COL4A2 | -4060 |
| MUSK | -4046 |
| MMP10 | -4027 |
| ITGB1 | -3975 |
| PECAM1 | -3952 |
| MFAP2 | -3911 |
| FBN2 | -3907 |
| ADAMTS16 | -3844 |
| PRKCA | -3721 |
| CAPN13 | -3574 |
| LTBP4 | -3524 |
| COL21A1 | -3520 |
| FMOD | -3500 |
| ELN | -3389 |
| LAMC3 | -3360 |
| ADAMTS9 | -3229 |
| COL9A3 | -3149 |
| JAM2 | -3138 |
| PLOD3 | -2909 |
| A2M | -2815 |
| TNN | -2746 |
| CASP3 | -2734 |
| ADAM10 | -2702 |
| LAMA2 | -2696 |
| LAMA1 | -2620 |
| COL8A1 | -2613 |
| TGFB1 | -2596 |
| ITGB6 | -2533 |
| COL23A1 | -2518 |
| COL5A2 | -2477 |
| DCN | -2338 |
| BMP7 | -2159 |
| MMP20 | -2152 |
| ITGA11 | -2032 |
| COL16A1 | -2009 |
| LAMC1 | -1988 |
| ITGB8 | -1950 |
| CAPN14 | -1948 |
| TIMP2 | -1917 |
| COL10A1 | -1914 |
| COL5A3 | -1735 |
| CAST | -1601 |
| FGG | -1569 |
| DDR2 | -1457 |
| CAPN12 | -1380 |
| IBSP | -1266 |
| LAMC2 | -1245 |
| COL4A4 | -1182 |
| ADAM9 | -1098 |
| P4HA2 | -1042 |
| DDR1 | -994 |
| TLL2 | -938 |
| COL24A1 | -507 |
| COL25A1 | -506 |
| VCAN | -377 |
| COL14A1 | -310 |
| OPTC | -191 |
| ITGAL | -179 |
| TNR | 4 |
| ADAM17 | 68 |
| EMILIN3 | 86 |
| NCAM1 | 197 |
| CD47 | 229 |
| LAMA3 | 278 |
| MMP13 | 343 |
| COL4A1 | 423 |
| COL11A1 | 498 |
| HAPLN1 | 513 |
| P3H2 | 640 |
| MMP16 | 652 |
| NRXN1 | 681 |
| CAPN1 | 753 |
| NID1 | 776 |
| CMA1 | 887 |
| NID2 | 950 |
| ITGAE | 1048 |
| FBN1 | 1148 |
| LAMA4 | 1257 |
| CDH1 | 1268 |
| LTBP1 | 1281 |
| MMP8 | 1292 |
| DST | 1382 |
| ICAM4 | 1474 |
| P4HA1 | 1531 |
| VCAM1 | 1631 |
| PSEN1 | 1709 |
| ITGA2B | 1745 |
| ADAM19 | 1795 |
| KLK7 | 1856 |
| APP | 1968 |
| ICAM2 | 2249 |
| SDC3 | 2347 |
| ITGA1 | 2738 |
| ICAM1 | 2878 |
| MFAP4 | 3006 |
| ADAMTS18 | 3153 |
| ICAM5 | 3270 |
| SPOCK3 | 3274 |
| TRAPPC4 | 3299 |
| LOX | 3348 |
| COL28A1 | 3380 |
| KLK2 | 3442 |
| PCOLCE2 | 3480 |
| BSG | 3484 |
| EFEMP1 | 3698 |
| ITGA9 | 3722 |
| MADCAM1 | 3743 |
| NTN4 | 3799 |
| KDR | 3919 |
| ACTN1 | 3938 |
| COL6A6 | 3975 |
| COMP | 4031 |
| CTSS | 4163 |
| MMP19 | 4228 |
| EFEMP2 | 4290 |
| CAPNS1 | 4378 |
| COL6A5 | 4441 |
| PDGFB | 4469 |
| ICAM3 | 4540 |
| EMILIN2 | 4572 |
| ITGB3 | 4581 |
| COL9A1 | 4680 |
| TTR | 4713 |
| SERPINE1 | 4724 |
| PPIB | 4755 |
| COL19A1 | 4779 |
| P4HB | 4781 |
| CTSK | 4849 |
| ITGA5 | 4854 |
| SDC2 | 4916 |
| CD44 | 5011 |
| MMP7 | 5101 |
| PRSS1 | 5174 |
| BMP10 | 5336 |
| ADAMTS5 | 5353 |
| LRP4 | 5364 |
| PLOD2 | 5365 |
| BMP4 | 5750 |
| FBLN5 | 5770 |
| BCAN | 5896 |
| MATN4 | 6009 |
| PLG | 6103 |
| COL4A3 | 6385 |
| MMP3 | 6549 |
| LUM | 6604 |
| P4HA3 | 6709 |
| MMP9 | 6737 |
| LOXL3 | 6904 |
| ADAMTS8 | 7036 |
| COL12A1 | 7114 |
| CTSL | 7520 |
| MFAP3 | 7619 |
| ADAMTS1 | 7635 |
| CAPN7 | 7733 |
| NCAN | 7768 |
| F11R | 7865 |
| ITGA8 | 7971 |
| TLL1 | 8337 |
| MATN3 | 8392 |
| ELANE | 8506 |
| CTSV | 8563 |
| ITGA4 | 8730 |
| CRTAP | 9041 |
| ITGA6 | 9290 |
| SPP1 | 9714 |
| CEACAM6 | 9942 |
| CTSG | 10382 |
REACTOME_OLFACTORY_SIGNALING_PATHWAY
| 628 | |
|---|---|
| set | REACTOME_OLFACTORY_SIGNALING_PATHWAY |
| setSize | 348 |
| pANOVA | 1.79e-06 |
| s.dist | -0.149 |
| p.adjustANOVA | 8.65e-05 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| OR8B4 | -11186.0 |
| OR1K1 | -11148.0 |
| OR5M8 | -11065.0 |
| OR4K15 | -10962.0 |
| OR2S2 | -10961.0 |
| OR10Z1 | -10938.0 |
| OR2T12 | -10858.0 |
| OR1L8 | -10789.0 |
| OR7E24 | -10785.5 |
| OR5C1 | -10781.0 |
| OR6Y1 | -10749.0 |
| OR4D5 | -10731.0 |
| OR51G2 | -10669.0 |
| OR10C1 | -10643.0 |
| OR14A16 | -10596.0 |
| OR52E2 | -10589.0 |
| OR10J3 | -10547.0 |
| OR1N1 | -10542.0 |
| OR10K2 | -10447.0 |
| OR52D1 | -10416.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| OR8B4 | -11186.0 |
| OR1K1 | -11148.0 |
| OR5M8 | -11065.0 |
| OR4K15 | -10962.0 |
| OR2S2 | -10961.0 |
| OR10Z1 | -10938.0 |
| OR2T12 | -10858.0 |
| OR1L8 | -10789.0 |
| OR7E24 | -10785.5 |
| OR5C1 | -10781.0 |
| OR6Y1 | -10749.0 |
| OR4D5 | -10731.0 |
| OR51G2 | -10669.0 |
| OR10C1 | -10643.0 |
| OR14A16 | -10596.0 |
| OR52E2 | -10589.0 |
| OR10J3 | -10547.0 |
| OR1N1 | -10542.0 |
| OR10K2 | -10447.0 |
| OR52D1 | -10416.0 |
| OR4E2 | -10401.0 |
| OR8A1 | -10334.0 |
| OR52A5 | -10261.5 |
| OR52L1 | -10250.0 |
| OR13J1 | -10213.0 |
| CNGB1 | -10188.0 |
| OR2G2 | -10183.0 |
| OR52R1 | -10163.0 |
| OR13C2 | -10111.0 |
| OR2T1 | -10057.0 |
| OR1J4 | -10042.0 |
| OR2G3 | -10029.0 |
| OR2L5 | -9940.0 |
| OR9I1 | -9840.0 |
| OR10A3 | -9825.0 |
| OR8K3 | -9752.0 |
| OR2A14 | -9641.0 |
| OR51E1 | -9509.0 |
| OR4A5 | -9480.0 |
| OR5K1 | -9392.0 |
| OR6C65 | -9374.0 |
| OR5B21 | -9372.0 |
| OR52J3 | -9371.0 |
| OR1G1 | -9308.0 |
| OR7D4 | -9301.0 |
| ADCY3 | -9298.0 |
| OR2W3 | -9288.0 |
| OR51I2 | -9282.0 |
| OR3A1 | -9211.0 |
| OR11L1 | -9195.0 |
| OR8D1 | -9117.0 |
| OR2M4 | -9065.0 |
| OR51F1 | -9055.0 |
| OR52H1 | -9028.0 |
| OR11H6 | -9023.0 |
| OR6M1 | -8809.0 |
| OR7G1 | -8736.0 |
| OR4K5 | -8706.0 |
| OR2Y1 | -8697.0 |
| OR8B2 | -8695.0 |
| OR10H1 | -8684.0 |
| OR56A3 | -8621.0 |
| OR2F2 | -8607.0 |
| OR6T1 | -8527.0 |
| OR52A1 | -8517.0 |
| RTP1 | -8482.0 |
| OR2AG2 | -8441.0 |
| OR52E6 | -8377.0 |
| OR6C68 | -8368.0 |
| OR51B4 | -8366.0 |
| OR52B6 | -8334.0 |
| OR13F1 | -8275.0 |
| OR12D3 | -8241.0 |
| OR1N2 | -8223.0 |
| OR6C1 | -8140.0 |
| RTP2 | -8123.0 |
| OR51I1 | -8087.0 |
| OR8B8 | -8081.0 |
| OR1L1 | -7980.0 |
| OR4D10 | -7975.0 |
| OR13G1 | -7921.0 |
| OR8D2 | -7746.0 |
| OR5J2 | -7715.0 |
| OR51G1 | -7708.0 |
| OR10K1 | -7675.0 |
| OR2T8 | -7631.0 |
| OR11A1 | -7622.0 |
| OR6C75 | -7609.0 |
| OR1L6 | -7571.0 |
| OR5M3 | -7531.0 |
| OR14I1 | -7384.0 |
| OR52K2 | -7353.0 |
| OR1Q1 | -7304.0 |
| OR1M1 | -7295.0 |
| OR5P3 | -7262.0 |
| OR5K2 | -7218.0 |
| OR11G2 | -7192.0 |
| OR10A5 | -7159.0 |
| OR2B11 | -7134.0 |
| OR5F1 | -7086.0 |
| OR2AP1 | -7063.0 |
| OR8J3 | -7021.0 |
| OR1L4 | -6997.0 |
| CNGA4 | -6855.0 |
| OR8J1 | -6843.0 |
| OR13C8 | -6806.0 |
| OR4L1 | -6795.0 |
| OR6C3 | -6790.0 |
| OR4K1 | -6764.0 |
| OR10V1 | -6629.0 |
| OR51B2 | -6597.0 |
| OR51F2 | -6578.0 |
| OR52B2 | -6547.0 |
| OR2T6 | -6536.0 |
| OR4F15 | -6481.0 |
| OR4M1 | -6438.0 |
| OR6C70 | -6391.0 |
| OR7C2 | -6339.0 |
| OR52I2 | -6192.0 |
| OR5T1 | -6188.0 |
| OR5M10 | -6180.0 |
| OR8H3 | -6171.0 |
| OR4N5 | -6088.0 |
| OR8K5 | -6074.0 |
| OR5L2 | -5998.0 |
| OR51M1 | -5996.0 |
| OR1C1 | -5930.0 |
| OR51S1 | -5865.0 |
| OR2A12 | -5841.0 |
| OR4S1 | -5779.0 |
| OR13C3 | -5597.0 |
| OR5AC2 | -5593.0 |
| OR5D18 | -5465.0 |
| OR7C1 | -5464.0 |
| OR52M1 | -5412.0 |
| OR4C3 | -5278.5 |
| OR2V2 | -5118.0 |
| OR5V1 | -5093.0 |
| OR5B2 | -5029.0 |
| OR10S1 | -5020.0 |
| OR5AR1 | -4978.0 |
| GNB1 | -4968.0 |
| OR51E2 | -4871.0 |
| OR2Z1 | -4841.0 |
| OR6F1 | -4755.0 |
| OR2M3 | -4751.0 |
| OR10H2 | -4681.0 |
| OR9Q1 | -4658.0 |
| OR10A2 | -4634.0 |
| OR56A5 | -4614.0 |
| OR2J2 | -4588.0 |
| OR5K4 | -4572.0 |
| OR5T2 | -4479.0 |
| OR5M1 | -4443.0 |
| OR6S1 | -4441.0 |
| OR52E8 | -4411.0 |
| OR2A5 | -4392.0 |
| OR10G4 | -4318.0 |
| OR5AN1 | -4222.0 |
| OR6X1 | -4214.0 |
| OR1D2 | -4209.0 |
| OR51V1 | -4184.0 |
| OR6K2 | -4172.0 |
| OR4D1 | -4092.0 |
| OR8U3 | -3922.0 |
| OR10A4 | -3822.0 |
| OR5B3 | -3818.0 |
| OR4K2 | -3731.0 |
| OR1J2 | -3701.0 |
| OR4D2 | -3646.0 |
| OR1I1 | -3555.0 |
| OR5W2 | -3539.0 |
| OR9G4 | -3488.0 |
| OR2G6 | -3349.0 |
| OR51T1 | -3301.0 |
| OR10AD1 | -3280.0 |
| OR6C2 | -3279.0 |
| OR1B1 | -3184.0 |
| OR4C6 | -3021.0 |
| OR2D3 | -3002.0 |
| OR5L1 | -2959.0 |
| OR5AP2 | -2953.0 |
| OR56B1 | -2948.0 |
| OR7G2 | -2920.0 |
| OR51D1 | -2826.0 |
| OR10G7 | -2785.0 |
| OR51Q1 | -2721.0 |
| OR6Q1 | -2714.0 |
| OR10H3 | -2712.0 |
| OR52N2 | -2641.0 |
| OR8G1 | -2554.0 |
| OR8U8 | -2383.0 |
| OR14C36 | -2348.0 |
| OR2D2 | -2288.0 |
| OR1E1 | -2260.0 |
| OR10X1 | -2204.0 |
| OR8H1 | -2076.0 |
| OR51B5 | -1934.0 |
| OR4C45 | -1868.0 |
| OR2C1 | -1865.0 |
| OR10H4 | -1850.0 |
| OR4A16 | -1830.0 |
| OR5D16 | -1817.0 |
| OR10P1 | -1771.0 |
| OR51L1 | -1745.0 |
| OR6N1 | -1718.0 |
| OR9A2 | -1711.0 |
| OR5B12 | -1660.0 |
| OR6A2 | -1604.0 |
| OR5M9 | -1570.0 |
| OR2C3 | -1562.0 |
| OR4C15 | -1495.0 |
| OR13A1 | -1408.0 |
| OR5M11 | -1257.0 |
| OR6V1 | -1018.0 |
| OR4X1 | -999.0 |
| OR7G3 | -996.0 |
| OR2K2 | -931.0 |
| OR7D2 | -835.0 |
| OR2T3 | -828.0 |
| OR7A5 | -690.0 |
| OR52K1 | -653.0 |
| OR52N1 | -490.0 |
| OR2H1 | -413.0 |
| OR2L13 | -321.0 |
| OR12D2 | -207.0 |
| OR51B6 | -37.0 |
| OR2M5 | 38.0 |
| OR4X2 | 87.0 |
| OR10H5 | 237.0 |
| OR10Q1 | 260.0 |
| OR9G1 | 323.5 |
| OR9G9 | 323.5 |
| OR8U1 | 492.0 |
| GNAL | 502.0 |
| OR2L8 | 1273.0 |
| OR2F1 | 1280.0 |
| OR3A3 | 1284.0 |
| OR2AE1 | 1390.0 |
| OR9Q2 | 1552.0 |
| OR13D1 | 1649.0 |
| OR4K17 | 1777.0 |
| OR5H6 | 1918.0 |
| OR4C16 | 1992.0 |
| OR56A1 | 2257.0 |
| GNG13 | 2324.0 |
| OR4D11 | 2396.0 |
| EBF1 | 2412.0 |
| OR4C12 | 2496.0 |
| OR2B3 | 2637.0 |
| OR6B3 | 2641.0 |
| OR1S1 | 2819.0 |
| OR6K6 | 2904.0 |
| OR1F1 | 2933.0 |
| OR52I1 | 3060.0 |
| OR5AS1 | 3082.0 |
| OR5P2 | 3105.0 |
| OR7A17 | 3250.0 |
| OR6N2 | 3377.0 |
| OR6P1 | 3439.0 |
| OR52W1 | 3584.0 |
| OR5I1 | 3604.0 |
| OR11H4 | 3639.0 |
| OR10G8 | 3813.0 |
| OR5A1 | 3818.0 |
| REEP1 | 3830.0 |
| OR1L3 | 3891.0 |
| OR5AU1 | 3922.0 |
| OR10A6 | 4052.0 |
| OR4B1 | 4145.0 |
| OR2M7 | 4292.0 |
| ANO2 | 4431.0 |
| OR6C74 | 4462.0 |
| LHX2 | 4657.0 |
| OR4N2 | 4702.0 |
| OR4A15 | 5167.0 |
| OR2T27 | 5572.0 |
| OR10A7 | 5629.0 |
| OR8S1 | 5659.0 |
| OR10G3 | 5673.0 |
| OR9K2 | 5767.0 |
| OR8K1 | 5793.0 |
| OR2W1 | 5824.0 |
| OR6C76 | 5857.0 |
| OR13C9 | 6007.0 |
| OR5AK2 | 6054.0 |
| OR2L2 | 6139.0 |
| OR1A1 | 6295.0 |
| OR52E4 | 6453.0 |
| OR51A7 | 6507.0 |
| OR2AK2 | 6602.0 |
| OR14J1 | 6618.0 |
| OR7A10 | 6647.0 |
| OR56B4 | 6666.0 |
| OR5D14 | 6986.0 |
| OR10W1 | 7040.0 |
| OR6C4 | 7379.0 |
| OR9A4 | 7471.0 |
| OR8G5 | 7824.0 |
| OR3A2 | 7848.0 |
| OR4K14 | 7932.0 |
| LDB1 | 8039.0 |
| OR2T11 | 8494.0 |
| OR2T33 | 8542.0 |
| OR13C4 | 8683.0 |
| OR5K3 | 8799.0 |
| OR10G2 | 8843.0 |
| OR51A2 | 8904.0 |
| OR4F6 | 8953.0 |
| OR6B2 | 9035.0 |
| OR1J1 | 9227.0 |
| OR8D4 | 9261.0 |
| OR10J1 | 9275.0 |
| OR1S2 | 9350.0 |
| OR2T4 | 9374.0 |
| OR2A2 | 9387.0 |
| OR2B2 | 9550.0 |
| OR2H2 | 9668.0 |
| OR10AG1 | 9689.0 |
| OR5H1 | 9730.0 |
| OR6B1 | 9744.0 |
| OR5A2 | 9746.0 |
| OR4D6 | 9821.0 |
| OR1A2 | 9949.0 |
| OR5H15 | 9987.0 |
| OR2AG1 | 10002.0 |
| OR2V1 | 10004.0 |
| OR5D13 | 10163.0 |
| OR5H2 | 10198.0 |
| OR6C6 | 10204.0 |
| OR56A4 | 10212.0 |
| OR1E2 | 10214.0 |
| OR10J5 | 10312.0 |
| OR4A47 | 10336.0 |
| OR10T2 | 10343.0 |
| OR2L3 | 10354.0 |
| OR5T3 | 10357.0 |
| OR2AT4 | 10394.0 |
| OR2M2 | 10398.0 |
| OR8B12 | 10421.0 |
| OR4C46 | 10425.0 |
| OR4D9 | 10485.0 |
| OR2B6 | 10514.0 |
| OR4K13 | 10515.0 |
| OR6K3 | 10535.0 |
| OR10G9 | 10536.0 |
| OR5B17 | 10574.0 |
| OR8I2 | 10622.0 |
REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS
| 810 | |
|---|---|
| set | REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS |
| setSize | 86 |
| pANOVA | 2.65e-06 |
| s.dist | 0.293 |
| p.adjustANOVA | 0.000124 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| UBB | 10269 |
| DCP2 | 10068 |
| ANP32A | 9558 |
| PSMB3 | 9282 |
| PSMA6 | 9088 |
| ZFP36L1 | 8993 |
| PSMA7 | 8947 |
| SET | 8922 |
| PSME2 | 8738 |
| PSMC5 | 8695 |
| UBC | 8680 |
| PSMA1 | 8676 |
| MAPK14 | 8531 |
| PSMD12 | 8377 |
| PSMB1 | 8157 |
| EXOSC1 | 8143 |
| HSPA1A | 8066 |
| PSMC4 | 8042 |
| HSPA8 | 7776 |
| XPO1 | 7555 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| UBB | 10269 |
| DCP2 | 10068 |
| ANP32A | 9558 |
| PSMB3 | 9282 |
| PSMA6 | 9088 |
| ZFP36L1 | 8993 |
| PSMA7 | 8947 |
| SET | 8922 |
| PSME2 | 8738 |
| PSMC5 | 8695 |
| UBC | 8680 |
| PSMA1 | 8676 |
| MAPK14 | 8531 |
| PSMD12 | 8377 |
| PSMB1 | 8157 |
| EXOSC1 | 8143 |
| HSPA1A | 8066 |
| PSMC4 | 8042 |
| HSPA8 | 7776 |
| XPO1 | 7555 |
| EXOSC5 | 7283 |
| EXOSC7 | 7271 |
| PSMB9 | 7201 |
| EXOSC3 | 6924 |
| UBA52 | 6901 |
| DIS3 | 6405 |
| PSMB7 | 6283 |
| RPS27A | 6223 |
| PSMB10 | 6211 |
| EXOSC4 | 6174 |
| ZFP36 | 6170 |
| YWHAZ | 6039 |
| HNRNPD | 6019 |
| PSMB8 | 6003 |
| EXOSC8 | 5963 |
| PSMD13 | 5916 |
| TNFSF13 | 5820 |
| PSMC6 | 5420 |
| PSMA4 | 4963 |
| PSMD7 | 4932 |
| PSMA3 | 4116 |
| TNPO1 | 3866 |
| KHSRP | 3662 |
| HSPB1 | 3432 |
| PSMB2 | 3326 |
| PSMB4 | 3049 |
| PSMC1 | 2987 |
| PSMA8 | 2379 |
| PSMD1 | 2144 |
| PSME4 | 2128 |
| PSMB5 | 2078 |
| PSMC3 | 1749 |
| SEM1 | 1657 |
| PSMC2 | 1653 |
| PSMD4 | 1403 |
| DCP1A | 1119 |
| PRKCD | 775 |
| PSMA5 | 665 |
| PSMA2 | 467 |
| PSMD3 | 274 |
| PABPC1 | 181 |
| EIF4G1 | 169 |
| PSMD14 | -192 |
| PSME3 | -576 |
| PSME1 | -840 |
| PARN | -1017 |
| PSMD6 | -1076 |
| PSMD11 | -1095 |
| PSMD5 | -1600 |
| YWHAB | -1708 |
| PSMD8 | -1715 |
| PSMD9 | -1897 |
| MAPKAPK2 | -1995 |
| EXOSC9 | -3019 |
| PRKCA | -3721 |
| EXOSC2 | -4135 |
| PSMF1 | -4178 |
| MAPK11 | -4242 |
| NUP214 | -4467 |
| XRN1 | -4996 |
| PSMB6 | -5356 |
| PSMD2 | -6144 |
| EXOSC6 | -6161 |
| ELAVL1 | -7938 |
| AKT1 | -10034 |
| PSMB11 | -10657 |
REACTOME_PROTEIN_LOCALIZATION
| 1461 | |
|---|---|
| set | REACTOME_PROTEIN_LOCALIZATION |
| setSize | 153 |
| pANOVA | 2.85e-06 |
| s.dist | 0.219 |
| p.adjustANOVA | 0.00013 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| SEC61B | 10414 |
| ACOT2 | 10299 |
| UBB | 10269 |
| TIMM23 | 10257 |
| GET3 | 9903 |
| COA4 | 9846 |
| TOMM5 | 9779 |
| PEX12 | 9757 |
| TOMM70 | 9733 |
| GRPEL2 | 9716 |
| ACOT8 | 9681 |
| SEC61G | 9264 |
| TIMM22 | 9114 |
| CS | 9092 |
| SERP1 | 9033 |
| SLC25A4 | 8905 |
| ABCD2 | 8839 |
| GET1 | 8746 |
| UBC | 8680 |
| ECH1 | 8633 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SEC61B | 10414 |
| ACOT2 | 10299 |
| UBB | 10269 |
| TIMM23 | 10257 |
| GET3 | 9903 |
| COA4 | 9846 |
| TOMM5 | 9779 |
| PEX12 | 9757 |
| TOMM70 | 9733 |
| GRPEL2 | 9716 |
| ACOT8 | 9681 |
| SEC61G | 9264 |
| TIMM22 | 9114 |
| CS | 9092 |
| SERP1 | 9033 |
| SLC25A4 | 8905 |
| ABCD2 | 8839 |
| GET1 | 8746 |
| UBC | 8680 |
| ECH1 | 8633 |
| TOMM40 | 8496 |
| PEX6 | 8464 |
| AGPS | 8293 |
| TOMM20 | 8182 |
| IDH1 | 8160 |
| IDE | 8145 |
| ATP5F1A | 8103 |
| SLC25A12 | 8071 |
| TOMM6 | 7984 |
| GRPEL1 | 7766 |
| ACOX1 | 7717 |
| PAM16 | 7643 |
| SLC27A2 | 7610 |
| GFER | 7565 |
| PEX13 | 7430 |
| TIMM21 | 7260 |
| UBA52 | 6901 |
| VAPA | 6826 |
| CHCHD7 | 6438 |
| PEX3 | 6371 |
| DNAJC19 | 6302 |
| ATAD1 | 6270 |
| RPS27A | 6223 |
| HSCB | 6092 |
| MTX2 | 6021 |
| CMC2 | 6002 |
| MTX1 | 5928 |
| HACL1 | 5808 |
| PEX16 | 5735 |
| GSTK1 | 5687 |
| ACOT4 | 5580 |
| CHCHD2 | 5436 |
| NDUFB8 | 5384 |
| MPV17 | 5183 |
| TIMM9 | 5180 |
| UBE2D3 | 5120 |
| COQ2 | 5117 |
| ATP5F1B | 5042 |
| AMACR | 5003 |
| TIMM50 | 4798 |
| TIMM8B | 4655 |
| PIPOX | 4508 |
| PXMP4 | 4465 |
| PEX26 | 4315 |
| PEX7 | 4252 |
| COA6 | 4148 |
| COX17 | 4056 |
| HAO1 | 3950 |
| TOMM22 | 3942 |
| CHCHD4 | 3932 |
| NUDT19 | 3877 |
| CYB5A | 3541 |
| TIMM10B | 3512 |
| PECR | 3468 |
| NUDT7 | 3304 |
| SCP2 | 2759 |
| CAT | 2753 |
| PEX11B | 2737 |
| SLC25A13 | 2706 |
| HSPA9 | 2683 |
| ACBD5 | 2679 |
| ECI2 | 2576 |
| SLC25A17 | 2517 |
| ZFAND6 | 2502 |
| DHRS4 | 2471 |
| TIMM10 | 2390 |
| PEX1 | 2369 |
| VAMP2 | 2227 |
| LONP2 | 2194 |
| APP | 1968 |
| STX1A | 1966 |
| PHYH | 1866 |
| FXN | 1814 |
| UBE2D2 | 1776 |
| STX5 | 1624 |
| HSPD1 | 1551 |
| TOMM7 | 1444 |
| EHHADH | 1430 |
| GNPAT | 1339 |
| DDO | 921 |
| CYC1 | 733 |
| LDHD | 516 |
| TYSND1 | 426 |
| PEX5 | 388 |
| ALDH3A2 | 377 |
| COX19 | 256 |
| ABCD3 | 200 |
| CAMLG | 143 |
| HSD17B4 | 81 |
| PAOX | -394 |
| ATP5MC1 | -686 |
| SAMM50 | -694 |
| CROT | -748 |
| BAAT | -1126 |
| TIMM17A | -1233 |
| TIMM13 | -1443 |
| PEX2 | -1581 |
| FIS1 | -2360 |
| PXMP2 | -3156 |
| BAG6 | -3333 |
| EPHX2 | -3508 |
| HMGCL | -3521 |
| SGTA | -4036 |
| VDAC1 | -4105 |
| CHCHD5 | -4127 |
| PMPCA | -4181 |
| PEX19 | -4557 |
| PMPCB | -5297 |
| UBE2D1 | -5677 |
| PEX10 | -5705 |
| MLYCD | -5732 |
| ACOX2 | -5850 |
| CRAT | -6055 |
| GDAP1 | -6311 |
| ACAA1 | -6549 |
| PEX14 | -6606 |
| NOS2 | -6829 |
| DECR2 | -6840 |
| BCS1L | -7429 |
| CHCHD3 | -7496 |
| CHCHD10 | -7596 |
| PRNP | -8110 |
| ACO2 | -8308 |
| GET4 | -8353 |
| OTOF | -8438 |
| TIMM44 | -8808 |
| HMOX1 | -8934 |
| AGXT | -9560 |
| ACOX3 | -9616 |
| PITRM1 | -9723 |
| UBE2J2 | -10164 |
| HAO2 | -10305 |
| DAO | -10703 |
REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE
| 1082 | |
|---|---|
| set | REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE |
| setSize | 125 |
| pANOVA | 3.51e-06 |
| s.dist | -0.24 |
| p.adjustANOVA | 0.000156 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TGM1 | -11009 |
| KRT79 | -10870 |
| PKP3 | -10850 |
| LCE1B | -10814 |
| KRT81 | -10803 |
| KRT15 | -10697 |
| LCE5A | -10617 |
| KRT78 | -10533 |
| KRT13 | -10364 |
| KRT80 | -10362 |
| LIPK | -10324 |
| KRT36 | -10319 |
| KRT85 | -10243 |
| KRT84 | -10006 |
| SPINK9 | -10001 |
| KRT77 | -9966 |
| KRT33A | -9857 |
| KRT82 | -9652 |
| KRT76 | -9481 |
| KRT39 | -9271 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TGM1 | -11009 |
| KRT79 | -10870 |
| PKP3 | -10850 |
| LCE1B | -10814 |
| KRT81 | -10803 |
| KRT15 | -10697 |
| LCE5A | -10617 |
| KRT78 | -10533 |
| KRT13 | -10364 |
| KRT80 | -10362 |
| LIPK | -10324 |
| KRT36 | -10319 |
| KRT85 | -10243 |
| KRT84 | -10006 |
| SPINK9 | -10001 |
| KRT77 | -9966 |
| KRT33A | -9857 |
| KRT82 | -9652 |
| KRT76 | -9481 |
| KRT39 | -9271 |
| LCE1F | -9238 |
| KRT5 | -9012 |
| KRT8 | -8987 |
| KRT35 | -8830 |
| KRT71 | -8570 |
| PPL | -8542 |
| FLG | -8474 |
| KRT86 | -8345 |
| EVPL | -8139 |
| KRT1 | -8090 |
| KRT26 | -7963 |
| FURIN | -7705 |
| KRT12 | -7550 |
| KRT14 | -7547 |
| CELA2A | -7541 |
| KRT74 | -7441 |
| PI3 | -7291 |
| KRT6B | -7142 |
| KRT4 | -7124 |
| CSTA | -6980 |
| KRT73 | -6975 |
| SPRR1A | -6954 |
| PRSS8 | -6952 |
| KRT33B | -6951 |
| KRT7 | -6776 |
| LCE2C | -6513 |
| DSC1 | -6483 |
| PKP2 | -6366 |
| PCSK6 | -6306 |
| LIPN | -6076 |
| CDSN | -6066 |
| JUP | -5959 |
| KRT37 | -5945 |
| LIPJ | -5844 |
| KAZN | -5840 |
| KRT18 | -4963 |
| SPINK6 | -4900 |
| LCE4A | -4727 |
| KRT31 | -4707 |
| KRT38 | -4632 |
| KRT20 | -4062 |
| KRT75 | -4028 |
| PKP4 | -3917 |
| LCE3B | -3858 |
| KLK12 | -3770 |
| LCE2B | -3755 |
| DSG3 | -3680 |
| LIPM | -3378 |
| DSC2 | -2910 |
| SPRR3 | -2725 |
| SPRR2E | -2689 |
| KRT40 | -2591 |
| KRT2 | -2367 |
| KRT9 | -2008 |
| ST14 | -1652 |
| LCE6A | -1633 |
| KRT16 | -1590 |
| PKP1 | -864 |
| KRT83 | -759 |
| KRT24 | -647 |
| DSC3 | -227 |
| KLK13 | -100 |
| KRT23 | -86 |
| SPRR1B | -49 |
| KLK14 | 32 |
| KRT27 | 54 |
| DSG1 | 120 |
| CAPN1 | 753 |
| KRT19 | 977 |
| KRT3 | 1089 |
| SPRR2D | 1189 |
| KRT25 | 1220 |
| KLK8 | 1697 |
| KRT32 | 2061 |
| TCHH | 2253 |
| KRT6A | 2455 |
| CASP14 | 2497 |
| KLK5 | 2816 |
| KRT17 | 3140 |
| SPRR2A | 3195 |
| KRT34 | 3344 |
| LCE3E | 3405 |
| DSG4 | 3490 |
| KRT28 | 3700 |
| LELP1 | 3821 |
| LCE1C | 4016 |
| CAPNS1 | 4378 |
| KRT6C | 4439 |
| DSP | 4653 |
| SPRR2G | 5114 |
| SPRR2F | 5317 |
| KRT10 | 5785 |
| IVL | 6164 |
| LCE2A | 6180 |
| SPINK5 | 6246 |
| LCE3D | 6553 |
| KRT72 | 6558 |
| TGM5 | 6917 |
| LCE1A | 7706 |
| DSG2 | 7935 |
| RPTN | 8450 |
| LCE2D | 8619 |
| LCE1E | 9501 |
| LCE3A | 10045 |
| PERP | 10250 |
REACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION
| 852 | |
|---|---|
| set | REACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION |
| setSize | 84 |
| pANOVA | 3.76e-06 |
| s.dist | 0.292 |
| p.adjustANOVA | 0.000159 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| H3C12 | 10132 |
| POLR1G | 10100 |
| TBP | 9764 |
| TAF1A | 9594 |
| H2BC14 | 9436 |
| H4C8 | 9408 |
| H2AC14 | 9305 |
| H2BC17 | 9247 |
| H3-3A | 9239 |
| POLR1H | 9171 |
| H3C3 | 9111 |
| POLR1C | 9086 |
| ACTB | 8973 |
| H2AZ1 | 8894 |
| POLR2L | 8803 |
| H2BC5 | 8646 |
| H4C4 | 8378 |
| H2BC4 | 7968 |
| POLR1E | 7847 |
| POLR2H | 7324 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| H3C12 | 10132.0 |
| POLR1G | 10100.0 |
| TBP | 9764.0 |
| TAF1A | 9594.0 |
| H2BC14 | 9436.0 |
| H4C8 | 9408.0 |
| H2AC14 | 9305.0 |
| H2BC17 | 9247.0 |
| H3-3A | 9239.0 |
| POLR1H | 9171.0 |
| H3C3 | 9111.0 |
| POLR1C | 9086.0 |
| ACTB | 8973.0 |
| H2AZ1 | 8894.0 |
| POLR2L | 8803.0 |
| H2BC5 | 8646.0 |
| H4C4 | 8378.0 |
| H2BC4 | 7968.0 |
| POLR1E | 7847.0 |
| POLR2H | 7324.0 |
| H2AC18 | 7261.5 |
| H2AC19 | 7261.5 |
| H2AC6 | 7006.0 |
| H2BC15 | 6756.0 |
| H4C3 | 6755.0 |
| BAZ1B | 6748.0 |
| H2BC9 | 6696.5 |
| H3C7 | 6696.5 |
| DDX21 | 6692.0 |
| H2AC4 | 6574.0 |
| H2AZ2 | 6477.0 |
| H4C5 | 6455.0 |
| POLR2E | 6038.0 |
| TAF1D | 5907.0 |
| POLR2K | 5369.0 |
| POLR1B | 5276.0 |
| H2BC3 | 5022.0 |
| H4C9 | 4853.0 |
| H4C16 | 4688.0 |
| H2AJ | 4666.0 |
| H2BC6 | 4552.0 |
| H4C2 | 4300.0 |
| H4C6 | 4018.0 |
| GSK3B | 4006.0 |
| POLR1D | 3965.0 |
| H2BC12 | 3661.0 |
| SF3B1 | 3294.0 |
| H2AC20 | 3275.0 |
| SMARCA5 | 3044.0 |
| H3C2 | 2976.0 |
| POLR1F | 2809.0 |
| H2BC11 | 2506.0 |
| H2BC21 | 1717.0 |
| TAF1B | 1327.0 |
| ERCC6 | 1069.0 |
| H2AX | 764.0 |
| H3C11 | 608.0 |
| KAT2B | 408.0 |
| DEK | 132.0 |
| H4C1 | -64.0 |
| POLR1A | -88.0 |
| H3C6 | -174.0 |
| H2BC10 | -630.0 |
| H3C8 | -1062.0 |
| EP300 | -1121.0 |
| H4C13 | -1134.0 |
| H3-3B | -1628.0 |
| H4C12 | -1933.0 |
| H3C1 | -2029.0 |
| H2BC13 | -3416.0 |
| H3C4 | -4187.0 |
| H2AC7 | -4211.0 |
| H2BC7 | -4211.0 |
| H2AC8 | -4264.0 |
| H2BC8 | -5026.0 |
| POLR2F | -5251.0 |
| MYBBP1A | -6842.0 |
| KAT2A | -7275.0 |
| H2BC26 | -7437.0 |
| MYO1C | -7966.0 |
| H2BC1 | -8099.0 |
| H3C10 | -8558.0 |
| H4C11 | -9168.0 |
| TAF1C | -9938.0 |
REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S
| 1150 | |
|---|---|
| set | REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S |
| setSize | 53 |
| pANOVA | 3.77e-06 |
| s.dist | 0.367 |
| p.adjustANOVA | 0.000159 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS12 | 10065 |
| EIF3J | 9988 |
| EIF4A1 | 9700 |
| RPSA | 9598 |
| EIF4H | 8713 |
| EIF2S2 | 8700 |
| EIF2S1 | 8607 |
| RPS18 | 8418 |
| RPS14 | 8367 |
| RPS28 | 8053 |
| RPS10 | 7422 |
| RPS9 | 7239 |
| RPS13 | 6745 |
| EIF3G | 6501 |
| RPS21 | 6312 |
| EIF3F | 6280 |
| RPS27A | 6223 |
| RPS23 | 6171 |
| RPS2 | 6145 |
| RPS3A | 5876 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS12 | 10065 |
| EIF3J | 9988 |
| EIF4A1 | 9700 |
| RPSA | 9598 |
| EIF4H | 8713 |
| EIF2S2 | 8700 |
| EIF2S1 | 8607 |
| RPS18 | 8418 |
| RPS14 | 8367 |
| RPS28 | 8053 |
| RPS10 | 7422 |
| RPS9 | 7239 |
| RPS13 | 6745 |
| EIF3G | 6501 |
| RPS21 | 6312 |
| EIF3F | 6280 |
| RPS27A | 6223 |
| RPS23 | 6171 |
| RPS2 | 6145 |
| RPS3A | 5876 |
| EIF3K | 5774 |
| RPS27L | 5650 |
| RPS16 | 5552 |
| FAU | 5376 |
| EIF3I | 5206 |
| EIF4E | 4924 |
| RPS11 | 4468 |
| RPS20 | 4174 |
| RPS15A | 4169 |
| RPS8 | 4117 |
| EIF3L | 3580 |
| RPS19 | 3558 |
| RPS5 | 3408 |
| RPS24 | 3357 |
| RPS7 | 3333 |
| EIF4A2 | 3182 |
| RPS29 | 2812 |
| RPS26 | 2583 |
| RPS27 | 2232 |
| RPS25 | 2059 |
| RPS6 | 1237 |
| EIF3M | 574 |
| PABPC1 | 181 |
| EIF4G1 | 169 |
| EIF3E | -214 |
| RPS3 | -935 |
| EIF4B | -1756 |
| RPS15 | -2768 |
| EIF3D | -4500 |
| EIF3B | -6053 |
| EIF4EBP1 | -6620 |
| EIF3A | -7122 |
| EIF3H | -7385 |
REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES
| 1135 | |
|---|---|
| set | REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES |
| setSize | 353 |
| pANOVA | 4.33e-06 |
| s.dist | 0.142 |
| p.adjustANOVA | 0.000178 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RPL39L | 10429 |
| PYCR2 | 10422 |
| RPLP1 | 10383 |
| RPL19 | 10237 |
| CKM | 10130 |
| GCDH | 10128 |
| RPL27A | 10126 |
| RPL38 | 10097 |
| SUOX | 10075 |
| RPS12 | 10065 |
| RPL27 | 10018 |
| NAGS | 9993 |
| RPL12 | 9972 |
| OAZ3 | 9892 |
| GOT2 | 9866 |
| RPL5 | 9847 |
| RPL10A | 9823 |
| LIPT1 | 9817 |
| RPSA | 9598 |
| RPL35A | 9504 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPL39L | 10429.0 |
| PYCR2 | 10422.0 |
| RPLP1 | 10383.0 |
| RPL19 | 10237.0 |
| CKM | 10130.0 |
| GCDH | 10128.0 |
| RPL27A | 10126.0 |
| RPL38 | 10097.0 |
| SUOX | 10075.0 |
| RPS12 | 10065.0 |
| RPL27 | 10018.0 |
| NAGS | 9993.0 |
| RPL12 | 9972.0 |
| OAZ3 | 9892.0 |
| GOT2 | 9866.0 |
| RPL5 | 9847.0 |
| RPL10A | 9823.0 |
| LIPT1 | 9817.0 |
| RPSA | 9598.0 |
| RPL35A | 9504.0 |
| RPL13 | 9355.0 |
| DIO3 | 9349.0 |
| TPH1 | 9314.0 |
| CDO1 | 9306.0 |
| PSMB3 | 9282.0 |
| SERINC3 | 9280.0 |
| GCAT | 9279.0 |
| RPL11 | 9263.0 |
| PSMA6 | 9088.0 |
| RPL34 | 8949.0 |
| PSMA7 | 8947.0 |
| HYKK | 8766.0 |
| PSME2 | 8738.0 |
| PSMC5 | 8695.0 |
| PSMA1 | 8676.0 |
| RPL36AL | 8546.5 |
| RPL18A | 8433.0 |
| RPS18 | 8418.0 |
| RPL7 | 8407.0 |
| PSMD12 | 8377.0 |
| RPS14 | 8367.0 |
| EEF1E1 | 8291.0 |
| DLD | 8214.0 |
| PSMB1 | 8157.0 |
| RPL37 | 8126.0 |
| SLC25A12 | 8071.0 |
| RPS28 | 8053.0 |
| PSMC4 | 8042.0 |
| DLST | 8002.0 |
| RPL7A | 7958.0 |
| SERINC1 | 7861.0 |
| RPL23 | 7819.0 |
| LIPT2 | 7808.0 |
| NNMT | 7807.0 |
| LARS1 | 7756.0 |
| GNMT | 7609.0 |
| RPL6 | 7585.0 |
| ASNS | 7511.0 |
| RPL28 | 7492.0 |
| SQOR | 7470.0 |
| RPLP0 | 7456.0 |
| RPS10 | 7422.0 |
| RIDA | 7331.0 |
| RPS9 | 7239.0 |
| PSMB9 | 7201.0 |
| SEPHS2 | 7166.0 |
| MCCC2 | 7163.0 |
| OAZ2 | 7078.0 |
| RPL3 | 7066.0 |
| ETHE1 | 7009.0 |
| CKB | 6933.0 |
| UBA52 | 6901.0 |
| MCCC1 | 6869.0 |
| RPL4 | 6839.0 |
| RPL23A | 6780.0 |
| RPS13 | 6745.0 |
| RPL32 | 6717.0 |
| ODC1 | 6556.0 |
| SRR | 6505.0 |
| CRYM | 6481.0 |
| SERINC5 | 6380.0 |
| RPS21 | 6312.0 |
| PSMB7 | 6283.0 |
| RPS27A | 6223.0 |
| PSMB10 | 6211.0 |
| AHCY | 6208.0 |
| RPS23 | 6171.0 |
| GOT1 | 6154.0 |
| RPS2 | 6145.0 |
| RPL8 | 6083.0 |
| PSMB8 | 6003.0 |
| ARG2 | 5976.0 |
| GLUL | 5964.0 |
| ARG1 | 5931.0 |
| PSMD13 | 5916.0 |
| RPS3A | 5876.0 |
| AIMP1 | 5852.0 |
| DHTKD1 | 5816.0 |
| ALDH6A1 | 5754.0 |
| RPS27L | 5650.0 |
| RPS16 | 5552.0 |
| ADO | 5529.0 |
| AADAT | 5498.0 |
| PSMC6 | 5420.0 |
| TPH2 | 5413.0 |
| RPL15 | 5410.0 |
| FAU | 5376.0 |
| PYCR3 | 5278.0 |
| CTH | 5261.0 |
| SLC3A2 | 5083.0 |
| AGMAT | 5046.0 |
| PSMA4 | 4963.0 |
| PSMD7 | 4932.0 |
| HIBADH | 4918.0 |
| RPL18 | 4825.0 |
| ALDH7A1 | 4659.0 |
| AMDHD1 | 4606.0 |
| DLAT | 4567.0 |
| RPL26 | 4557.0 |
| DARS1 | 4553.0 |
| BCKDHB | 4527.0 |
| PIPOX | 4508.0 |
| RPL17 | 4473.0 |
| RPS11 | 4468.0 |
| RPL21 | 4396.0 |
| PDHB | 4345.0 |
| RPS20 | 4174.0 |
| RPS15A | 4169.0 |
| RPS8 | 4117.0 |
| PSMA3 | 4116.0 |
| GATM | 4089.0 |
| KARS1 | 4073.0 |
| RPL30 | 3957.0 |
| HAO1 | 3950.0 |
| AMD1 | 3870.0 |
| PSPH | 3787.0 |
| RPL26L1 | 3710.0 |
| IYD | 3634.0 |
| RPS19 | 3558.0 |
| PNMT | 3424.0 |
| RPS5 | 3408.0 |
| RPS24 | 3357.0 |
| RPS7 | 3333.0 |
| PSMB2 | 3326.0 |
| CARNMT1 | 3313.0 |
| MTRR | 3296.0 |
| DUOX2 | 3139.0 |
| DBT | 3138.0 |
| BCKDHA | 3114.0 |
| HNMT | 3080.0 |
| RPL37A | 3063.0 |
| PSMB4 | 3049.0 |
| PSMC1 | 2987.0 |
| SLC44A1 | 2943.0 |
| RPL22 | 2864.0 |
| GPT2 | 2839.0 |
| RPS29 | 2812.0 |
| GADL1 | 2745.0 |
| KMO | 2721.0 |
| SLC25A13 | 2706.0 |
| RPL35 | 2694.0 |
| NDUFAB1 | 2668.0 |
| SLC36A4 | 2617.0 |
| RPS26 | 2583.0 |
| GLUD1 | 2523.0 |
| CPS1 | 2388.0 |
| PSMA8 | 2379.0 |
| DMGDH | 2362.0 |
| RPS27 | 2232.0 |
| PSMD1 | 2144.0 |
| PSME4 | 2128.0 |
| PSMB5 | 2078.0 |
| RPS25 | 2059.0 |
| PPM1K | 1921.0 |
| NQO1 | 1911.0 |
| RARS1 | 1805.0 |
| RPL22L1 | 1785.0 |
| PSMC3 | 1749.0 |
| APIP | 1668.0 |
| SEM1 | 1657.0 |
| PSMC2 | 1653.0 |
| NAALAD2 | 1628.0 |
| TYRP1 | 1612.0 |
| AZIN2 | 1599.0 |
| GLS2 | 1585.0 |
| PSMD4 | 1403.0 |
| HOGA1 | 1283.0 |
| RPS6 | 1237.0 |
| AZIN1 | 1223.0 |
| BHMT2 | 1210.0 |
| AFMID | 1172.0 |
| GLDC | 1138.0 |
| ASRGL1 | 984.0 |
| PRODH2 | 957.0 |
| OGDH | 923.0 |
| DDO | 921.0 |
| RPL24 | 901.0 |
| DIO2 | 841.0 |
| SLC25A21 | 758.0 |
| PSMA5 | 665.0 |
| MRI1 | 615.0 |
| PSMA2 | 467.0 |
| TXNRD1 | 306.0 |
| ENOPH1 | 276.0 |
| PSMD3 | 274.0 |
| RPLP2 | 141.0 |
| KYAT3 | 122.0 |
| TAT | 84.0 |
| ALDH18A1 | -5.0 |
| IDO2 | -21.0 |
| FMO1 | -76.0 |
| PSMD14 | -192.0 |
| ACAD8 | -239.0 |
| SLC5A5 | -307.0 |
| GAMT | -342.0 |
| BBOX1 | -374.0 |
| PAOX | -394.0 |
| RPL9 | -399.0 |
| TH | -532.0 |
| PAH | -563.0 |
| ACADSB | -571.0 |
| PSME3 | -576.0 |
| RPL29 | -634.0 |
| LIAS | -662.0 |
| SERINC2 | -676.0 |
| PSME1 | -840.0 |
| RPL36 | -891.0 |
| FOLH1 | -910.0 |
| CHDH | -919.0 |
| RPS3 | -935.0 |
| HAL | -1046.0 |
| PSMD6 | -1076.0 |
| PSMD11 | -1095.0 |
| SRM | -1110.0 |
| PHGDH | -1148.0 |
| HIBCH | -1159.0 |
| SLC25A44 | -1164.0 |
| SDSL | -1232.0 |
| AASS | -1258.0 |
| GLS | -1363.0 |
| ASS1 | -1568.0 |
| DCT | -1575.0 |
| PSMD5 | -1600.0 |
| TYR | -1637.0 |
| CGA | -1675.0 |
| PSTK | -1685.0 |
| PSMD8 | -1715.0 |
| PAPSS2 | -1765.0 |
| FAH | -1804.0 |
| PSMD9 | -1897.0 |
| PDHX | -2106.0 |
| TDO2 | -2220.0 |
| RIMKLB | -2321.0 |
| SECISBP2 | -2406.0 |
| OCA2 | -2425.0 |
| RPL41 | -2639.0 |
| RPL13A | -2765.5 |
| RPS15 | -2768.0 |
| BCAT1 | -2775.0 |
| ASPA | -2820.0 |
| NMRAL1 | -2851.0 |
| KYNU | -3013.0 |
| OAT | -3068.0 |
| ADI1 | -3111.0 |
| PAPSS1 | -3129.0 |
| PXMP2 | -3156.0 |
| GCSH | -3357.0 |
| TXN2 | -3426.0 |
| SLC25A15 | -3473.0 |
| RPL31 | -3475.0 |
| ACAT1 | -3596.0 |
| PDHA2 | -3678.0 |
| IDO1 | -3684.0 |
| MTAP | -3734.0 |
| NAT8L | -3857.0 |
| GSR | -4001.0 |
| PYCR1 | -4006.0 |
| EPRS1 | -4013.0 |
| SLC6A12 | -4142.0 |
| PSMF1 | -4178.0 |
| SLC25A2 | -4225.0 |
| IVD | -4275.0 |
| HDC | -4325.0 |
| OAZ1 | -4382.0 |
| SEPSECS | -4396.0 |
| RIMKLA | -4548.0 |
| BCKDK | -4559.0 |
| HAAO | -4573.0 |
| AGXT2 | -4612.0 |
| SMOX | -4690.0 |
| AIMP2 | -4699.0 |
| ALDH9A1 | -4702.0 |
| GSTZ1 | -4759.0 |
| MTR | -4793.0 |
| DIO1 | -4889.0 |
| PRODH | -5041.0 |
| MAT1A | -5153.0 |
| IL4I1 | -5160.0 |
| SLC6A11 | -5205.0 |
| CSAD | -5207.0 |
| HGD | -5293.0 |
| PSMB6 | -5356.0 |
| PCBD1 | -5528.0 |
| BHMT | -5690.0 |
| RPL14 | -5770.0 |
| TSHB | -5886.0 |
| SCLY | -6035.0 |
| MPST | -6096.0 |
| PSMD2 | -6144.0 |
| CKMT1B | -6169.0 |
| ACMSD | -6264.0 |
| TPO | -6383.0 |
| HPD | -6516.0 |
| CARNS1 | -6651.0 |
| AMT | -6794.0 |
| ALDH4A1 | -6909.0 |
| IARS1 | -6986.0 |
| BCAT2 | -7091.0 |
| AANAT | -7117.0 |
| CKMT2 | -7336.0 |
| AUH | -7371.0 |
| SDS | -7726.0 |
| SERINC4 | -7732.0 |
| TST | -7780.0 |
| SLC6A7 | -8024.0 |
| DBH | -8085.0 |
| DUOX1 | -8216.0 |
| MARS1 | -8262.0 |
| PSAT1 | -8473.0 |
| PHYKPL | -8476.0 |
| SHMT1 | -8743.0 |
| SARDH | -8791.0 |
| SLC45A2 | -9085.0 |
| QDPR | -9127.0 |
| GPT | -9312.0 |
| ASPG | -9439.0 |
| EEFSEC | -9450.0 |
| GRHPR | -9462.0 |
| SLC25A10 | -9520.0 |
| AGXT | -9560.0 |
| TSTD1 | -9588.0 |
| ECHS1 | -9701.0 |
| ASL | -9728.0 |
| FTCD | -9787.0 |
| KYAT1 | -9798.0 |
| SLC7A5 | -9823.0 |
| UROC1 | -9911.0 |
| INMT | -10126.0 |
| DDC | -10245.0 |
| PSMB11 | -10657.0 |
| DAO | -10703.0 |
| RPL3L | -10862.0 |
| RPL10L | -10981.0 |
REACTOME_M_PHASE
| 1096 | |
|---|---|
| set | REACTOME_M_PHASE |
| setSize | 398 |
| pANOVA | 5.79e-06 |
| s.dist | 0.132 |
| p.adjustANOVA | 0.000232 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| MZT2B | 10648 |
| TUBB8 | 10619 |
| TUBB4B | 10587 |
| TUBG1 | 10349 |
| UBB | 10269 |
| TUBG2 | 10264 |
| MZT2A | 10253 |
| H3C12 | 10132 |
| ENSA | 10067 |
| NDC80 | 10032 |
| PPP2R5B | 9946 |
| AURKB | 9516 |
| H2BC14 | 9436 |
| H4C8 | 9408 |
| TUBA4A | 9371 |
| TPR | 9369 |
| NUP35 | 9338 |
| B9D2 | 9336 |
| H2AC14 | 9305 |
| PSMB3 | 9282 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MZT2B | 10648.0 |
| TUBB8 | 10619.0 |
| TUBB4B | 10587.0 |
| TUBG1 | 10349.0 |
| UBB | 10269.0 |
| TUBG2 | 10264.0 |
| MZT2A | 10253.0 |
| H3C12 | 10132.0 |
| ENSA | 10067.0 |
| NDC80 | 10032.0 |
| PPP2R5B | 9946.0 |
| AURKB | 9516.0 |
| H2BC14 | 9436.0 |
| H4C8 | 9408.0 |
| TUBA4A | 9371.0 |
| TPR | 9369.0 |
| NUP35 | 9338.0 |
| B9D2 | 9336.0 |
| H2AC14 | 9305.0 |
| PSMB3 | 9282.0 |
| TUBB3 | 9276.0 |
| H2BC17 | 9247.0 |
| NUP107 | 9241.0 |
| H3-3A | 9239.0 |
| H3C3 | 9111.0 |
| PSMA6 | 9088.0 |
| NSL1 | 9074.0 |
| PSMA7 | 8947.0 |
| ZWINT | 8941.0 |
| SET | 8922.0 |
| H2AZ1 | 8894.0 |
| LPIN2 | 8830.0 |
| CENPM | 8748.0 |
| PSME2 | 8738.0 |
| NUP43 | 8731.0 |
| PSMC5 | 8695.0 |
| UBC | 8680.0 |
| LMNB1 | 8677.0 |
| PSMA1 | 8676.0 |
| H2BC5 | 8646.0 |
| NCAPH | 8634.0 |
| TUBB2B | 8597.0 |
| ANAPC16 | 8396.0 |
| H4C4 | 8378.0 |
| PSMD12 | 8377.0 |
| CENPL | 8278.0 |
| SPC25 | 8222.0 |
| NUP153 | 8165.0 |
| SMC2 | 8159.0 |
| PSMB1 | 8157.0 |
| TUBA4B | 8052.0 |
| BANF1 | 8044.0 |
| PSMC4 | 8042.0 |
| KIF23 | 8010.0 |
| TUBB6 | 7982.0 |
| H2BC4 | 7968.0 |
| RAB1B | 7855.0 |
| NEDD1 | 7854.0 |
| CTDNEP1 | 7850.0 |
| CCP110 | 7652.0 |
| NUP155 | 7642.0 |
| CENPC | 7622.0 |
| RAB1A | 7593.0 |
| CDK1 | 7556.0 |
| XPO1 | 7555.0 |
| CEP70 | 7517.0 |
| ZW10 | 7491.0 |
| CHMP2B | 7377.0 |
| CEP135 | 7341.0 |
| H2AC18 | 7261.5 |
| H2AC19 | 7261.5 |
| ANAPC10 | 7259.0 |
| PSMB9 | 7201.0 |
| SKA1 | 7174.0 |
| MAPRE1 | 7157.0 |
| H2AC6 | 7006.0 |
| CDC26 | 6989.0 |
| SIRT2 | 6984.0 |
| UBA52 | 6901.0 |
| TUBA8 | 6874.0 |
| DSN1 | 6819.0 |
| ANAPC1 | 6773.0 |
| CENPA | 6757.0 |
| H2BC15 | 6756.0 |
| H4C3 | 6755.0 |
| MZT1 | 6742.0 |
| H2BC9 | 6696.5 |
| H3C7 | 6696.5 |
| SPAST | 6615.0 |
| H2AC4 | 6574.0 |
| H2AZ2 | 6477.0 |
| H4C5 | 6455.0 |
| BUB1B | 6390.0 |
| HAUS2 | 6338.0 |
| PSMB7 | 6283.0 |
| DYNC1I2 | 6238.0 |
| RPS27A | 6223.0 |
| PSMB10 | 6211.0 |
| CHMP2A | 6123.0 |
| ITGB3BP | 6053.0 |
| PSMB8 | 6003.0 |
| NCAPG | 6001.0 |
| PDS5A | 5985.0 |
| KPNB1 | 5984.0 |
| PSMD13 | 5916.0 |
| SKA2 | 5899.0 |
| NUP54 | 5663.0 |
| CSNK2B | 5641.0 |
| SPC24 | 5620.0 |
| HAUS1 | 5604.0 |
| NUP50 | 5527.0 |
| PSMC6 | 5420.0 |
| CNEP1R1 | 5093.0 |
| H2BC3 | 5022.0 |
| PSMA4 | 4963.0 |
| PSMD7 | 4932.0 |
| PDS5B | 4900.0 |
| CCNB1 | 4895.0 |
| H4C9 | 4853.0 |
| PPP2R5D | 4812.0 |
| HAUS8 | 4763.0 |
| TUBB | 4729.0 |
| USO1 | 4719.0 |
| H4C16 | 4688.0 |
| CENPH | 4681.0 |
| H2AJ | 4666.0 |
| KIF20A | 4654.0 |
| PTTG1 | 4580.0 |
| CEP290 | 4569.0 |
| H2BC6 | 4552.0 |
| POM121 | 4393.0 |
| SGO2 | 4365.0 |
| H4C2 | 4300.0 |
| PAFAH1B1 | 4299.0 |
| SGO1 | 4191.0 |
| SSNA1 | 4164.0 |
| PSMA3 | 4116.0 |
| CDCA5 | 4069.0 |
| H4C6 | 4018.0 |
| IST1 | 3986.0 |
| KIF18A | 3914.0 |
| TNPO1 | 3866.0 |
| CHMP7 | 3806.0 |
| CEP43 | 3778.0 |
| POM121C | 3776.0 |
| CEP63 | 3745.0 |
| RAN | 3664.0 |
| H2BC12 | 3661.0 |
| CENPE | 3612.0 |
| CHMP4C | 3587.0 |
| DYNC1LI1 | 3543.0 |
| MIS12 | 3447.0 |
| NUP133 | 3422.0 |
| PSMB2 | 3326.0 |
| MAD2L1 | 3317.0 |
| H2AC20 | 3275.0 |
| SMC4 | 3232.0 |
| PMF1 | 3229.0 |
| TUBA1B | 3208.0 |
| NUP205 | 3185.0 |
| CENPQ | 3129.0 |
| AKAP9 | 3085.0 |
| PSMB4 | 3049.0 |
| EML4 | 2994.0 |
| PSMC1 | 2987.0 |
| CEP76 | 2979.0 |
| H3C2 | 2976.0 |
| CEP41 | 2951.0 |
| PRKAR2B | 2917.0 |
| PLK4 | 2895.0 |
| WAPL | 2823.0 |
| ANAPC15 | 2703.0 |
| YWHAG | 2674.0 |
| HAUS4 | 2589.0 |
| UBE2S | 2530.0 |
| H2BC11 | 2506.0 |
| FBXO5 | 2479.0 |
| YWHAE | 2415.0 |
| NDC1 | 2410.0 |
| PSMA8 | 2379.0 |
| TAOK1 | 2306.0 |
| CDC27 | 2297.0 |
| LEMD3 | 2290.0 |
| DCTN2 | 2252.0 |
| CHMP4B | 2240.0 |
| RPS27 | 2232.0 |
| PSMD1 | 2144.0 |
| MAPK1 | 2130.0 |
| PSME4 | 2128.0 |
| CDCA8 | 2118.0 |
| PSMB5 | 2078.0 |
| CEP152 | 2073.0 |
| HSP90AA1 | 2049.0 |
| ARPP19 | 2036.0 |
| CENPK | 2007.0 |
| CCNB2 | 1987.0 |
| CDC23 | 1913.0 |
| DYNC1I1 | 1903.0 |
| NUF2 | 1796.0 |
| PPP2R5A | 1763.0 |
| PSMC3 | 1749.0 |
| ZWILCH | 1732.0 |
| CENPT | 1722.0 |
| H2BC21 | 1717.0 |
| SEM1 | 1657.0 |
| PSMC2 | 1653.0 |
| ACTR1A | 1641.0 |
| NEK9 | 1636.0 |
| ANAPC5 | 1528.0 |
| CEP57 | 1429.0 |
| CLASP2 | 1411.0 |
| PSMD4 | 1403.0 |
| ANAPC7 | 1287.0 |
| NUP88 | 1277.0 |
| CENPN | 1269.0 |
| RAE1 | 1215.0 |
| CEP78 | 1192.0 |
| RANBP2 | 1191.0 |
| CEP250 | 1153.0 |
| UBE2E1 | 974.0 |
| BUB1 | 814.0 |
| H2AX | 764.0 |
| PSMA5 | 665.0 |
| NUP160 | 618.0 |
| H3C11 | 608.0 |
| BLZF1 | 483.0 |
| PSMA2 | 467.0 |
| ALMS1 | 439.0 |
| NUP98 | 368.0 |
| PSMD3 | 274.0 |
| MASTL | 209.0 |
| KNL1 | 199.0 |
| PPP2R1A | 156.0 |
| CLIP1 | 109.0 |
| KNTC1 | 17.0 |
| H4C1 | -64.0 |
| CENPS | -129.0 |
| ANAPC11 | -133.0 |
| CDC20 | -136.0 |
| VRK1 | -142.0 |
| RB1 | -156.0 |
| RAD21 | -162.0 |
| H3C6 | -174.0 |
| PRKCB | -186.0 |
| PSMD14 | -192.0 |
| NUDC | -237.0 |
| VRK2 | -276.0 |
| KMT5A | -305.0 |
| TMPO | -330.0 |
| CSNK2A1 | -415.0 |
| TUBB4A | -521.0 |
| PSME3 | -576.0 |
| H2BC10 | -630.0 |
| SEH1L | -682.0 |
| PLK1 | -736.0 |
| UBE2C | -737.0 |
| NDEL1 | -822.0 |
| PSME1 | -840.0 |
| H3C8 | -1062.0 |
| PSMD6 | -1076.0 |
| PSMD11 | -1095.0 |
| NUP42 | -1128.0 |
| H4C13 | -1134.0 |
| TUBA1A | -1153.0 |
| PPP2CA | -1246.0 |
| RCC2 | -1275.0 |
| DYNLL1 | -1359.0 |
| SDCCAG8 | -1442.0 |
| STAG1 | -1532.0 |
| NME7 | -1541.0 |
| PSMD5 | -1600.0 |
| AHCTF1 | -1614.0 |
| H3-3B | -1628.0 |
| NIPBL | -1671.0 |
| CENPU | -1684.0 |
| PSMD8 | -1715.0 |
| CENPF | -1726.0 |
| ANAPC4 | -1773.0 |
| NUP37 | -1790.0 |
| TUBGCP5 | -1801.0 |
| BUB3 | -1861.0 |
| PSMD9 | -1897.0 |
| SMC3 | -1902.0 |
| H4C12 | -1933.0 |
| H3C1 | -2029.0 |
| PPP2CB | -2234.0 |
| KIF2A | -2336.0 |
| SEC13 | -2354.0 |
| DCTN3 | -2491.0 |
| CDC16 | -2545.0 |
| TUBB2A | -2758.0 |
| CENPO | -2939.0 |
| PPP2R5C | -3049.0 |
| HAUS3 | -3083.0 |
| NEK7 | -3155.0 |
| CLASP1 | -3176.0 |
| RAB2A | -3216.0 |
| LMNA | -3342.0 |
| PCM1 | -3371.0 |
| H2BC13 | -3416.0 |
| RCC1 | -3494.0 |
| CHMP3 | -3516.0 |
| SUMO1 | -3519.0 |
| TUBGCP3 | -3551.0 |
| HAUS5 | -3591.0 |
| CENPJ | -3638.0 |
| PRKCA | -3721.0 |
| CSNK1E | -3790.0 |
| CEP192 | -3866.0 |
| CNTRL | -3902.0 |
| LBR | -3946.0 |
| HAUS6 | -4053.0 |
| PSMF1 | -4178.0 |
| H3C4 | -4187.0 |
| CSNK2A2 | -4208.0 |
| H2AC7 | -4211.0 |
| H2BC7 | -4211.0 |
| NUMA1 | -4256.0 |
| H2AC8 | -4264.0 |
| LEMD2 | -4384.0 |
| NUP214 | -4467.0 |
| NINL | -4489.0 |
| PPP2R2A | -4580.0 |
| H3-4 | -4629.0 |
| PPP2R5E | -4824.0 |
| TUBA1C | -4828.0 |
| NDE1 | -4898.0 |
| CKAP5 | -4910.0 |
| CDK5RAP2 | -4929.0 |
| H2BC8 | -5026.0 |
| NUP93 | -5201.0 |
| DCTN1 | -5208.0 |
| TUBGCP4 | -5230.0 |
| PSMB6 | -5356.0 |
| NCAPD3 | -5426.0 |
| DYNC1LI2 | -5447.0 |
| MCPH1 | -5458.0 |
| UBE2D1 | -5677.0 |
| CENPP | -5812.0 |
| PPP1CC | -5826.0 |
| BIRC5 | -5845.0 |
| NUP62 | -6129.0 |
| PSMD2 | -6144.0 |
| PRKACA | -6164.0 |
| GORASP2 | -6220.0 |
| SPDL1 | -6490.0 |
| CEP131 | -6548.0 |
| DYNLL2 | -6691.0 |
| CHMP4A | -6869.0 |
| PPP2R1B | -6960.0 |
| NUP188 | -7120.0 |
| H2BC26 | -7437.0 |
| TUBAL3 | -7519.0 |
| TUBGCP6 | -7578.0 |
| NCAPD2 | -7592.0 |
| NEK6 | -7679.0 |
| TUBGCP2 | -7682.0 |
| NCAPG2 | -7697.0 |
| CHMP6 | -7771.0 |
| UBE2I | -7784.0 |
| NUP58 | -7794.0 |
| RANGAP1 | -7942.0 |
| VPS4A | -7952.0 |
| CC2D1B | -7972.0 |
| SFI1 | -7974.0 |
| TUBA3C | -7998.0 |
| GOLGA2 | -8023.0 |
| H2BC1 | -8099.0 |
| LPIN1 | -8128.0 |
| TUBB1 | -8166.0 |
| NUP85 | -8221.0 |
| AAAS | -8286.0 |
| ANKLE2 | -8314.0 |
| NUP210 | -8505.0 |
| NCAPH2 | -8547.0 |
| H3C10 | -8558.0 |
| KIF2C | -8565.0 |
| TUBA3E | -8617.0 |
| ESPL1 | -8663.0 |
| INCENP | -8729.0 |
| CEP164 | -8761.0 |
| PCNT | -8799.0 |
| MAD1L1 | -8829.0 |
| NEK2 | -8905.0 |
| CSNK1D | -9021.0 |
| PPP2R2D | -9167.0 |
| H4C11 | -9168.0 |
| ODF2 | -9272.0 |
| GORASP1 | -9292.0 |
| CEP72 | -9493.0 |
| DYNC1H1 | -9522.0 |
| ANAPC2 | -9561.0 |
| MAU2 | -9682.0 |
| MAPK3 | -9797.0 |
| KIF2B | -10419.0 |
| LPIN3 | -10540.0 |
| PSMB11 | -10657.0 |
| TUBA3D | -10666.0 |
REACTOME_SARS_COV_1_INFECTION
| 1539 | |
|---|---|
| set | REACTOME_SARS_COV_1_INFECTION |
| setSize | 136 |
| pANOVA | 5.96e-06 |
| s.dist | 0.225 |
| p.adjustANOVA | 0.000233 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| UBB | 10269 |
| RPS12 | 10065 |
| TOMM70 | 9733 |
| PYCARD | 9642 |
| RPSA | 9598 |
| EEF1A1 | 9508 |
| RCAN3 | 9132 |
| NFKBIA | 9116 |
| IFIH1 | 8998 |
| UBC | 8680 |
| CANX | 8449 |
| RPS18 | 8418 |
| YWHAH | 8406 |
| IRF3 | 8402 |
| RPS14 | 8367 |
| RIPK3 | 8285 |
| PCBP2 | 8264 |
| CAV1 | 8242 |
| SIKE1 | 8122 |
| PPIH | 8060 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| UBB | 10269 |
| RPS12 | 10065 |
| TOMM70 | 9733 |
| PYCARD | 9642 |
| RPSA | 9598 |
| EEF1A1 | 9508 |
| RCAN3 | 9132 |
| NFKBIA | 9116 |
| IFIH1 | 8998 |
| UBC | 8680 |
| CANX | 8449 |
| RPS18 | 8418 |
| YWHAH | 8406 |
| IRF3 | 8402 |
| RPS14 | 8367 |
| RIPK3 | 8285 |
| PCBP2 | 8264 |
| CAV1 | 8242 |
| SIKE1 | 8122 |
| PPIH | 8060 |
| RPS28 | 8053 |
| SP1 | 7917 |
| PPIG | 7844 |
| ST6GAL1 | 7829 |
| CTSL | 7520 |
| PRKCSH | 7461 |
| MGAT1 | 7426 |
| RPS10 | 7422 |
| CHMP2B | 7377 |
| ZCRB1 | 7346 |
| RPS9 | 7239 |
| GSK3A | 7107 |
| HNRNPA1 | 6967 |
| UBA52 | 6901 |
| RPS13 | 6745 |
| SMAD4 | 6630 |
| ST6GALNAC2 | 6434 |
| FKBP1A | 6399 |
| RPS21 | 6312 |
| RPS27A | 6223 |
| RPS23 | 6171 |
| RPS2 | 6145 |
| CHMP2A | 6123 |
| YWHAZ | 6039 |
| KPNB1 | 5984 |
| RPS3A | 5876 |
| RPS27L | 5650 |
| RPS16 | 5552 |
| PSMC6 | 5420 |
| FAU | 5376 |
| MOGS | 5312 |
| IRAK2 | 5303 |
| PPIB | 4755 |
| SERPINE1 | 4724 |
| GANAB | 4538 |
| ITCH | 4511 |
| PPIA | 4505 |
| RPS11 | 4468 |
| TBK1 | 4287 |
| RPS20 | 4174 |
| RPS15A | 4169 |
| RPS8 | 4117 |
| NMI | 4102 |
| GSK3B | 4006 |
| PALS1 | 3977 |
| CHMP7 | 3806 |
| CHMP4C | 3587 |
| RPS19 | 3558 |
| NPM1 | 3501 |
| RPS5 | 3408 |
| RPS24 | 3357 |
| RPS7 | 3333 |
| PARP8 | 3054 |
| PARP10 | 2843 |
| RPS29 | 2812 |
| YWHAG | 2674 |
| RPS26 | 2583 |
| YWHAE | 2415 |
| CHMP4B | 2240 |
| RPS27 | 2232 |
| RPS25 | 2059 |
| DDX5 | 1661 |
| RPS6 | 1237 |
| BCL2L1 | 707 |
| BST2 | 636 |
| NFKB1 | 12 |
| PARP9 | -113 |
| RB1 | -156 |
| PIK3C3 | -472 |
| ST6GALNAC4 | -707 |
| BECN1 | -781 |
| RPS3 | -935 |
| KPNA2 | -967 |
| YWHAQ | -1078 |
| EP300 | -1121 |
| PIK3R4 | -1122 |
| VHL | -1609 |
| MAP1LC3B | -1634 |
| YWHAB | -1708 |
| UVRAG | -1993 |
| CASP1 | -2295 |
| TMPRSS2 | -2508 |
| MAVS | -2509 |
| RIGI | -2535 |
| TRAF6 | -2592 |
| PARP4 | -2718 |
| RPS15 | -2768 |
| TKFC | -2784 |
| ST6GALNAC3 | -2901 |
| PARP16 | -3123 |
| TRIM25 | -3391 |
| NLRP3 | -3412 |
| CHMP3 | -3516 |
| SUMO1 | -3519 |
| STING1 | -3751 |
| PARP14 | -3766 |
| ST3GAL1 | -4952 |
| VCP | -5021 |
| TRAF3 | -5135 |
| ST3GAL3 | -5377 |
| ST3GAL2 | -5472 |
| IKBKE | -5538 |
| RUNX1 | -5564 |
| PDPK1 | -5927 |
| RELA | -6000 |
| PARP6 | -6281 |
| CHMP4A | -6869 |
| SMAD3 | -7487 |
| CHMP6 | -7771 |
| UBE2I | -7784 |
| RIPK1 | -7795 |
| PKLR | -7988 |
| SFN | -8815 |
| ST3GAL4 | -8858 |
| SFTPD | -9151 |
| GALNT1 | -9461 |
REACTOME_MEIOTIC_RECOMBINATION
| 1433 | |
|---|---|
| set | REACTOME_MEIOTIC_RECOMBINATION |
| setSize | 80 |
| pANOVA | 7.44e-06 |
| s.dist | 0.29 |
| p.adjustANOVA | 0.000284 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| H3C12 | 10132.0 |
| CDK4 | 10023.0 |
| MSH4 | 9802.0 |
| RPA2 | 9599.0 |
| H2BC14 | 9436.0 |
| H4C8 | 9408.0 |
| H2AC14 | 9305.0 |
| H2BC17 | 9247.0 |
| H3-3A | 9239.0 |
| H3C3 | 9111.0 |
| H2AZ1 | 8894.0 |
| PSMC3IP | 8888.0 |
| H2BC5 | 8646.0 |
| PRDM9 | 8545.0 |
| H4C4 | 8378.0 |
| H2BC4 | 7968.0 |
| H2AC18 | 7261.5 |
| H2AC19 | 7261.5 |
| H2AC6 | 7006.0 |
| TEX15 | 7001.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| H3C12 | 10132.0 |
| CDK4 | 10023.0 |
| MSH4 | 9802.0 |
| RPA2 | 9599.0 |
| H2BC14 | 9436.0 |
| H4C8 | 9408.0 |
| H2AC14 | 9305.0 |
| H2BC17 | 9247.0 |
| H3-3A | 9239.0 |
| H3C3 | 9111.0 |
| H2AZ1 | 8894.0 |
| PSMC3IP | 8888.0 |
| H2BC5 | 8646.0 |
| PRDM9 | 8545.0 |
| H4C4 | 8378.0 |
| H2BC4 | 7968.0 |
| H2AC18 | 7261.5 |
| H2AC19 | 7261.5 |
| H2AC6 | 7006.0 |
| TEX15 | 7001.0 |
| H2BC15 | 6756.0 |
| H4C3 | 6755.0 |
| H2BC9 | 6696.5 |
| H3C7 | 6696.5 |
| H2AC4 | 6574.0 |
| H2AZ2 | 6477.0 |
| H4C5 | 6455.0 |
| CDK2 | 6121.0 |
| RBBP8 | 5966.0 |
| BRCA1 | 5239.0 |
| RPA3 | 5112.0 |
| H2BC3 | 5022.0 |
| H4C9 | 4853.0 |
| H4C16 | 4688.0 |
| H2AJ | 4666.0 |
| MRE11 | 4573.0 |
| H2BC6 | 4552.0 |
| MLH1 | 4436.0 |
| H4C2 | 4300.0 |
| H4C6 | 4018.0 |
| RAD51C | 3899.0 |
| H2BC12 | 3661.0 |
| ATM | 3539.0 |
| SPO11 | 3481.0 |
| H2AC20 | 3275.0 |
| MND1 | 3204.0 |
| H3C2 | 2976.0 |
| H2BC11 | 2506.0 |
| BLM | 2402.0 |
| TOP3A | 2260.0 |
| DMC1 | 1808.0 |
| H2BC21 | 1717.0 |
| RAD50 | 807.0 |
| H2AX | 764.0 |
| H3C11 | 608.0 |
| H4C1 | -64.0 |
| RPA1 | -66.0 |
| H3C6 | -174.0 |
| H2BC10 | -630.0 |
| H3C8 | -1062.0 |
| H4C13 | -1134.0 |
| BRCA2 | -1342.0 |
| H3-3B | -1628.0 |
| H4C12 | -1933.0 |
| H3C1 | -2029.0 |
| RAD51 | -2618.0 |
| H2BC13 | -3416.0 |
| MLH3 | -4151.0 |
| H3C4 | -4187.0 |
| H2AC7 | -4211.0 |
| H2BC7 | -4211.0 |
| H2AC8 | -4264.0 |
| MSH5 | -4346.0 |
| H3-4 | -4629.0 |
| NBN | -4811.0 |
| H2BC8 | -5026.0 |
| H2BC26 | -7437.0 |
| H2BC1 | -8099.0 |
| H3C10 | -8558.0 |
| H4C11 | -9168.0 |
REACTOME_TCR_SIGNALING
| 391 | |
|---|---|
| set | REACTOME_TCR_SIGNALING |
| setSize | 113 |
| pANOVA | 9.38e-06 |
| s.dist | 0.241 |
| p.adjustANOVA | 0.000342 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CD3D | 10487 |
| GRAP2 | 10477 |
| UBB | 10269 |
| LCK | 9872 |
| HLA-DQA1 | 9800 |
| FYB1 | 9666 |
| HLA-DRA | 9628 |
| CD3G | 9519 |
| VASP | 9510 |
| PSMB3 | 9282 |
| TRAT1 | 9129 |
| NFKBIA | 9116 |
| PSMA6 | 9088 |
| CD3E | 8984 |
| PSMA7 | 8947 |
| PSME2 | 8738 |
| PSMC5 | 8695 |
| UBC | 8680 |
| PSMA1 | 8676 |
| CD247 | 8533 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CD3D | 10487 |
| GRAP2 | 10477 |
| UBB | 10269 |
| LCK | 9872 |
| HLA-DQA1 | 9800 |
| FYB1 | 9666 |
| HLA-DRA | 9628 |
| CD3G | 9519 |
| VASP | 9510 |
| PSMB3 | 9282 |
| TRAT1 | 9129 |
| NFKBIA | 9116 |
| PSMA6 | 9088 |
| CD3E | 8984 |
| PSMA7 | 8947 |
| PSME2 | 8738 |
| PSMC5 | 8695 |
| UBC | 8680 |
| PSMA1 | 8676 |
| CD247 | 8533 |
| PSMD12 | 8377 |
| ITK | 8200 |
| PSMB1 | 8157 |
| PAG1 | 8063 |
| PSMC4 | 8042 |
| UBE2V1 | 7929 |
| LCP2 | 7597 |
| CSK | 7315 |
| PSMB9 | 7201 |
| HLA-DPA1 | 6998 |
| UBA52 | 6901 |
| PSMB7 | 6283 |
| RPS27A | 6223 |
| PSMB10 | 6211 |
| PSMB8 | 6003 |
| BCL10 | 5938 |
| PSMD13 | 5916 |
| PTPRC | 5747 |
| PSMC6 | 5420 |
| PRKCQ | 5380 |
| SKP1 | 5377 |
| PIK3R1 | 4993 |
| LAT | 4991 |
| PSMA4 | 4963 |
| PSMD7 | 4932 |
| FBXW11 | 4901 |
| PSMA3 | 4116 |
| INPP5D | 4037 |
| HLA-DPB1 | 3903 |
| PTEN | 3814 |
| UBE2N | 3457 |
| PSMB2 | 3326 |
| PSMB4 | 3049 |
| PSMC1 | 2987 |
| CUL1 | 2567 |
| MALT1 | 2381 |
| PSMA8 | 2379 |
| PSMD1 | 2144 |
| PSME4 | 2128 |
| PSMB5 | 2078 |
| UBE2D2 | 1776 |
| PSMC3 | 1749 |
| SEM1 | 1657 |
| PSMC2 | 1653 |
| PSMD4 | 1403 |
| PIK3CA | 863 |
| PSMA5 | 665 |
| RIPK2 | 566 |
| PSMA2 | 467 |
| CDC34 | 443 |
| PLCG2 | 414 |
| PSMD3 | 274 |
| ENAH | 193 |
| NFKB1 | 12 |
| MAP3K7 | -189 |
| PSMD14 | -192 |
| BTRC | -218 |
| HLA-DQB1 | -290 |
| PTPRJ | -388 |
| PSME3 | -576 |
| PLCG1 | -770 |
| PSME1 | -840 |
| PSMD6 | -1076 |
| PTPN22 | -1083 |
| PSMD11 | -1095 |
| PIK3R2 | -1207 |
| NCK1 | -1237 |
| PSMD5 | -1600 |
| HLA-DQB2 | -1694 |
| PSMD8 | -1715 |
| PSMD9 | -1897 |
| PAK1 | -1927 |
| HLA-DRB5 | -2428 |
| TRAF6 | -2592 |
| HLA-DRB1 | -3080 |
| EVL | -3424 |
| PSMF1 | -4178 |
| PAK2 | -5084 |
| HLA-DQA2 | -5247 |
| TAB2 | -5288 |
| PSMB6 | -5356 |
| UBE2D1 | -5677 |
| PDPK1 | -5927 |
| RELA | -6000 |
| PSMD2 | -6144 |
| CD101 | -6308 |
| IKBKB | -6328 |
| CHUK | -6586 |
| PIK3CB | -6669 |
| ZAP70 | -6920 |
| CD4 | -9440 |
| CARD11 | -9975 |
| PSMB11 | -10657 |
REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION
| 64 | |
|---|---|
| set | REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION |
| setSize | 98 |
| pANOVA | 9.38e-06 |
| s.dist | 0.259 |
| p.adjustANOVA | 0.000342 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| S100A8 | 10448 |
| SEC61B | 10414 |
| UBB | 10269 |
| MYD88 | 10003 |
| SNAP23 | 9904 |
| CALR | 9479 |
| PSMB3 | 9282 |
| SEC61G | 9264 |
| CD14 | 9158 |
| PSMA6 | 9088 |
| PSMA7 | 8947 |
| HLA-G | 8760 |
| PSME2 | 8738 |
| PSMC5 | 8695 |
| UBC | 8680 |
| PSMA1 | 8676 |
| HLA-F | 8642 |
| HMGB1 | 8590 |
| CTSV | 8563 |
| B2M | 8487 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| S100A8 | 10448 |
| SEC61B | 10414 |
| UBB | 10269 |
| MYD88 | 10003 |
| SNAP23 | 9904 |
| CALR | 9479 |
| PSMB3 | 9282 |
| SEC61G | 9264 |
| CD14 | 9158 |
| PSMA6 | 9088 |
| PSMA7 | 8947 |
| HLA-G | 8760 |
| PSME2 | 8738 |
| PSMC5 | 8695 |
| UBC | 8680 |
| PSMA1 | 8676 |
| HLA-F | 8642 |
| HMGB1 | 8590 |
| CTSV | 8563 |
| B2M | 8487 |
| PSMD12 | 8377 |
| PSMB1 | 8157 |
| PSMC4 | 8042 |
| S100A9 | 7718 |
| VAMP8 | 7623 |
| CTSL | 7520 |
| PSMB9 | 7201 |
| HLA-E | 7027 |
| UBA52 | 6901 |
| TAP1 | 6858 |
| PSMB7 | 6283 |
| RPS27A | 6223 |
| PSMB10 | 6211 |
| PSMB8 | 6003 |
| PSMD13 | 5916 |
| TIRAP | 5789 |
| SEC61A1 | 5685 |
| STX4 | 5594 |
| PSMC6 | 5420 |
| PSMA4 | 4963 |
| PSMD7 | 4932 |
| TAPBP | 4250 |
| CTSS | 4163 |
| PSMA3 | 4116 |
| TLR1 | 3974 |
| LNPEP | 3770 |
| CYBA | 3616 |
| PSMB2 | 3326 |
| TLR4 | 3293 |
| SEC22B | 3236 |
| PSMB4 | 3049 |
| HLA-C | 3024 |
| PSMC1 | 2987 |
| TLR6 | 2621 |
| PSMA8 | 2379 |
| PSMD1 | 2144 |
| PSME4 | 2128 |
| PSMB5 | 2078 |
| PSMC3 | 1749 |
| SEM1 | 1657 |
| PSMC2 | 1653 |
| HLA-B | 1510 |
| PSMD4 | 1403 |
| S100A1 | 1263 |
| PSMA5 | 665 |
| PSMA2 | 467 |
| PSMD3 | 274 |
| PSMD14 | -192 |
| HLA-A | -480 |
| PSME3 | -576 |
| PSME1 | -840 |
| PSMD6 | -1076 |
| PSMD11 | -1095 |
| LY96 | -1328 |
| VAMP3 | -1554 |
| FGG | -1569 |
| PSMD5 | -1600 |
| PSMD8 | -1715 |
| PSMD9 | -1897 |
| NCF2 | -2936 |
| TAP2 | -3368 |
| PSMF1 | -4178 |
| ITGAV | -4331 |
| FGB | -4775 |
| FGA | -4954 |
| PSMB6 | -5356 |
| ITGB5 | -5382 |
| PSMD2 | -6144 |
| IKBKB | -6328 |
| CHUK | -6586 |
| CD36 | -6940 |
| NCF4 | -7083 |
| PDIA3 | -7499 |
| TLR2 | -7832 |
| MRC2 | -7877 |
| SEC61A2 | -8538 |
| PSMB11 | -10657 |
| CD207 | -10713 |
REACTOME_PERK_REGULATES_GENE_EXPRESSION
| 621 | |
|---|---|
| set | REACTOME_PERK_REGULATES_GENE_EXPRESSION |
| setSize | 31 |
| pANOVA | 1.02e-05 |
| s.dist | 0.458 |
| p.adjustANOVA | 0.000364 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CCL2 | 10549 |
| DCP2 | 10068 |
| CXCL8 | 9514 |
| EIF2S2 | 8700 |
| DDIT3 | 8615 |
| EIF2S1 | 8607 |
| CEBPB | 8342 |
| EXOSC1 | 8143 |
| ASNS | 7511 |
| EXOSC5 | 7283 |
| EXOSC7 | 7271 |
| EXOSC3 | 6924 |
| HSPA5 | 6918 |
| ATF4 | 6627 |
| DIS3 | 6405 |
| EXOSC4 | 6174 |
| EXOSC8 | 5963 |
| HERPUD1 | 5844 |
| CEBPG | 4662 |
| EIF2AK3 | 4291 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CCL2 | 10549 |
| DCP2 | 10068 |
| CXCL8 | 9514 |
| EIF2S2 | 8700 |
| DDIT3 | 8615 |
| EIF2S1 | 8607 |
| CEBPB | 8342 |
| EXOSC1 | 8143 |
| ASNS | 7511 |
| EXOSC5 | 7283 |
| EXOSC7 | 7271 |
| EXOSC3 | 6924 |
| HSPA5 | 6918 |
| ATF4 | 6627 |
| DIS3 | 6405 |
| EXOSC4 | 6174 |
| EXOSC8 | 5963 |
| HERPUD1 | 5844 |
| CEBPG | 4662 |
| EIF2AK3 | 4291 |
| IGFBP1 | 3785 |
| KHSRP | 3662 |
| NFYB | 3373 |
| ATF3 | 2309 |
| NFYA | 629 |
| ATF6 | 294 |
| NFYC | -421 |
| PARN | -1017 |
| EXOSC9 | -3019 |
| EXOSC2 | -4135 |
| EXOSC6 | -6161 |
REACTOME_SCF_SKP2_MEDIATED_DEGRADATION_OF_P27_P21
| 298 | |
|---|---|
| set | REACTOME_SCF_SKP2_MEDIATED_DEGRADATION_OF_P27_P21 |
| setSize | 59 |
| pANOVA | 1.15e-05 |
| s.dist | 0.33 |
| p.adjustANOVA | 4e-04 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| UBB | 10269 |
| CDK4 | 10023 |
| CKS1B | 9971 |
| PSMB3 | 9282 |
| PSMA6 | 9088 |
| PSMA7 | 8947 |
| PSME2 | 8738 |
| PSMC5 | 8695 |
| UBC | 8680 |
| PSMA1 | 8676 |
| SKP2 | 8386 |
| PSMD12 | 8377 |
| PSMB1 | 8157 |
| PSMC4 | 8042 |
| CDKN1B | 7523 |
| PSMB9 | 7201 |
| UBA52 | 6901 |
| PSMB7 | 6283 |
| RPS27A | 6223 |
| PSMB10 | 6211 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| UBB | 10269 |
| CDK4 | 10023 |
| CKS1B | 9971 |
| PSMB3 | 9282 |
| PSMA6 | 9088 |
| PSMA7 | 8947 |
| PSME2 | 8738 |
| PSMC5 | 8695 |
| UBC | 8680 |
| PSMA1 | 8676 |
| SKP2 | 8386 |
| PSMD12 | 8377 |
| PSMB1 | 8157 |
| PSMC4 | 8042 |
| CDKN1B | 7523 |
| PSMB9 | 7201 |
| UBA52 | 6901 |
| PSMB7 | 6283 |
| RPS27A | 6223 |
| PSMB10 | 6211 |
| CDK2 | 6121 |
| PSMB8 | 6003 |
| PSMD13 | 5916 |
| PSMC6 | 5420 |
| SKP1 | 5377 |
| PSMA4 | 4963 |
| PSMD7 | 4932 |
| PSMA3 | 4116 |
| CCNA1 | 3453 |
| PSMB2 | 3326 |
| PSMB4 | 3049 |
| PSMC1 | 2987 |
| CUL1 | 2567 |
| PSMD1 | 2144 |
| PSMB5 | 2078 |
| PSMC3 | 1749 |
| SEM1 | 1657 |
| PSMC2 | 1653 |
| PSMD4 | 1403 |
| CCND1 | 1077 |
| PSMA5 | 665 |
| CCNA2 | 521 |
| PSMA2 | 467 |
| CCNE2 | 369 |
| PSMD3 | 274 |
| PSMD14 | -192 |
| PSME3 | -576 |
| PSME1 | -840 |
| PSMD6 | -1076 |
| PSMD11 | -1095 |
| CCNE1 | -1241 |
| PSMD5 | -1600 |
| PSMD8 | -1715 |
| PSMD9 | -1897 |
| CDKN1A | -3505 |
| PSMF1 | -4178 |
| PSMB6 | -5356 |
| PSMD2 | -6144 |
| PTK6 | -10535 |
REACTOME_NEGATIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION
| 853 | |
|---|---|
| set | REACTOME_NEGATIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION |
| setSize | 100 |
| pANOVA | 1.17e-05 |
| s.dist | 0.254 |
| p.adjustANOVA | 4e-04 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| H3C12 | 10132 |
| POLR1G | 10100 |
| TBP | 9764 |
| GTF2H3 | 9734 |
| TAF1A | 9594 |
| SAP30L | 9506 |
| H2BC14 | 9436 |
| H4C8 | 9408 |
| H2AC14 | 9305 |
| SAP30 | 9292 |
| H2BC17 | 9247 |
| H3-3A | 9239 |
| POLR1H | 9171 |
| H3C3 | 9111 |
| POLR1C | 9086 |
| H2AZ1 | 8894 |
| POLR2L | 8803 |
| H2BC5 | 8646 |
| H4C4 | 8378 |
| H2BC4 | 7968 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| H3C12 | 10132.0 |
| POLR1G | 10100.0 |
| TBP | 9764.0 |
| GTF2H3 | 9734.0 |
| TAF1A | 9594.0 |
| SAP30L | 9506.0 |
| H2BC14 | 9436.0 |
| H4C8 | 9408.0 |
| H2AC14 | 9305.0 |
| SAP30 | 9292.0 |
| H2BC17 | 9247.0 |
| H3-3A | 9239.0 |
| POLR1H | 9171.0 |
| H3C3 | 9111.0 |
| POLR1C | 9086.0 |
| H2AZ1 | 8894.0 |
| POLR2L | 8803.0 |
| H2BC5 | 8646.0 |
| H4C4 | 8378.0 |
| H2BC4 | 7968.0 |
| POLR1E | 7847.0 |
| SIN3A | 7575.0 |
| SAP130 | 7389.0 |
| POLR2H | 7324.0 |
| H2AC18 | 7261.5 |
| H2AC19 | 7261.5 |
| H2AC6 | 7006.0 |
| H2BC15 | 6756.0 |
| H4C3 | 6755.0 |
| H2BC9 | 6696.5 |
| H3C7 | 6696.5 |
| H2AC4 | 6574.0 |
| H2AZ2 | 6477.0 |
| H4C5 | 6455.0 |
| POLR2E | 6038.0 |
| TAF1D | 5907.0 |
| RRP8 | 5817.0 |
| CCNH | 5625.0 |
| POLR2K | 5369.0 |
| POLR1B | 5276.0 |
| H2BC3 | 5022.0 |
| H4C9 | 4853.0 |
| H4C16 | 4688.0 |
| H2AJ | 4666.0 |
| H2BC6 | 4552.0 |
| H4C2 | 4300.0 |
| H4C6 | 4018.0 |
| POLR1D | 3965.0 |
| TTF1 | 3679.0 |
| H2BC12 | 3661.0 |
| GTF2H4 | 3554.0 |
| H2AC20 | 3275.0 |
| SMARCA5 | 3044.0 |
| H3C2 | 2976.0 |
| GTF2H5 | 2954.0 |
| POLR1F | 2809.0 |
| H2BC11 | 2506.0 |
| HDAC2 | 2488.0 |
| MNAT1 | 2449.0 |
| GTF2H1 | 2440.0 |
| H2BC21 | 1717.0 |
| ARID4B | 1666.0 |
| TAF1B | 1327.0 |
| CDK7 | 909.0 |
| H2AX | 764.0 |
| H3C11 | 608.0 |
| H4C1 | -64.0 |
| POLR1A | -88.0 |
| H3C6 | -174.0 |
| H2BC10 | -630.0 |
| UBTF | -1032.0 |
| H3C8 | -1062.0 |
| H4C13 | -1134.0 |
| ERCC3 | -1589.0 |
| H3-3B | -1628.0 |
| H4C12 | -1933.0 |
| H3C1 | -2029.0 |
| SAP18 | -2669.0 |
| SAP30BP | -2690.0 |
| H2BC13 | -3416.0 |
| SUDS3 | -3897.0 |
| H3C4 | -4187.0 |
| H2AC7 | -4211.0 |
| H2BC7 | -4211.0 |
| H2AC8 | -4264.0 |
| SIRT1 | -4337.0 |
| DNMT3B | -4850.0 |
| H2BC8 | -5026.0 |
| POLR2F | -5251.0 |
| HDAC1 | -5289.0 |
| BAZ2A | -5726.0 |
| SIN3B | -6003.0 |
| MBD2 | -6704.0 |
| H2BC26 | -7437.0 |
| H2BC1 | -8099.0 |
| ERCC2 | -8106.0 |
| H3C10 | -8558.0 |
| H4C11 | -9168.0 |
| DNMT1 | -9212.0 |
| TAF1C | -9938.0 |
REACTOME_UCH_PROTEINASES
| 1002 | |
|---|---|
| set | REACTOME_UCH_PROTEINASES |
| setSize | 99 |
| pANOVA | 1.28e-05 |
| s.dist | 0.254 |
| p.adjustANOVA | 0.000429 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| NEDD8 | 10361 |
| UBB | 10269 |
| H2AC17 | 9828 |
| TGFBR1 | 9750 |
| ASXL1 | 9465 |
| H2AC14 | 9305 |
| PSMB3 | 9282 |
| PSMA6 | 9088 |
| ACTB | 8973 |
| PSMA7 | 8947 |
| PSME2 | 8738 |
| PSMC5 | 8695 |
| UBC | 8680 |
| PSMA1 | 8676 |
| INO80B | 8387 |
| PSMD12 | 8377 |
| PSMB1 | 8157 |
| H2AC16 | 8075 |
| PSMC4 | 8042 |
| H2AC11 | 8024 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| NEDD8 | 10361.0 |
| UBB | 10269.0 |
| H2AC17 | 9828.0 |
| TGFBR1 | 9750.0 |
| ASXL1 | 9465.0 |
| H2AC14 | 9305.0 |
| PSMB3 | 9282.0 |
| PSMA6 | 9088.0 |
| ACTB | 8973.0 |
| PSMA7 | 8947.0 |
| PSME2 | 8738.0 |
| PSMC5 | 8695.0 |
| UBC | 8680.0 |
| PSMA1 | 8676.0 |
| INO80B | 8387.0 |
| PSMD12 | 8377.0 |
| PSMB1 | 8157.0 |
| H2AC16 | 8075.0 |
| PSMC4 | 8042.0 |
| H2AC11 | 8024.0 |
| UCHL5 | 7893.0 |
| ACTL6A | 7882.0 |
| H2AC15 | 7723.0 |
| MBD6 | 7576.0 |
| H2AC18 | 7261.5 |
| H2AC19 | 7261.5 |
| PSMB9 | 7201.0 |
| H2AC6 | 7006.0 |
| UBA52 | 6901.0 |
| H2AC4 | 6574.0 |
| PSMB7 | 6283.0 |
| RPS27A | 6223.0 |
| PSMB10 | 6211.0 |
| PSMB8 | 6003.0 |
| PSMD13 | 5916.0 |
| TGFBR2 | 5843.0 |
| ASXL2 | 5491.0 |
| PSMC6 | 5420.0 |
| PSMA4 | 4963.0 |
| PSMD7 | 4932.0 |
| TFPT | 4744.0 |
| KDM1B | 4306.0 |
| PSMA3 | 4116.0 |
| ACTR5 | 3365.0 |
| PSMB2 | 3326.0 |
| H2AC20 | 3275.0 |
| H2AC21 | 3071.0 |
| PSMB4 | 3049.0 |
| PSMC1 | 2987.0 |
| PSMA8 | 2379.0 |
| SENP8 | 2335.0 |
| PSMD1 | 2144.0 |
| PSME4 | 2128.0 |
| PSMB5 | 2078.0 |
| UCHL3 | 1977.0 |
| PSMC3 | 1749.0 |
| SEM1 | 1657.0 |
| PSMC2 | 1653.0 |
| RUVBL1 | 1408.0 |
| PSMD4 | 1403.0 |
| INO80E | 986.0 |
| PSMA5 | 665.0 |
| INO80C | 660.0 |
| PSMA2 | 467.0 |
| PSMD3 | 274.0 |
| PSMD14 | -192.0 |
| SMAD7 | -244.0 |
| H2AC13 | -254.0 |
| PSME3 | -576.0 |
| MBD5 | -590.0 |
| UCHL1 | -720.0 |
| PSME1 | -840.0 |
| PSMD6 | -1076.0 |
| PSMD11 | -1095.0 |
| INO80 | -1381.0 |
| PSMD5 | -1600.0 |
| PSMD8 | -1715.0 |
| PSMD9 | -1897.0 |
| INO80D | -1946.0 |
| ACTR8 | -2237.0 |
| YY1 | -2274.0 |
| TGFB1 | -2596.0 |
| USP15 | -3579.0 |
| FOXK2 | -3672.0 |
| NFRKB | -3686.0 |
| H2AC12 | -3780.0 |
| PSMF1 | -4178.0 |
| H2AC7 | -4211.0 |
| H2AC8 | -4264.0 |
| H2AC25 | -5103.0 |
| PSMB6 | -5356.0 |
| BAP1 | -5618.0 |
| BARD1 | -6121.0 |
| PSMD2 | -6144.0 |
| FOXK1 | -6430.0 |
| MCRS1 | -6922.0 |
| H2AC1 | -7658.0 |
| ADRM1 | -8470.0 |
| PSMB11 | -10657.0 |
REACTOME_SARS_COV_2_MODULATES_HOST_TRANSLATION_MACHINERY
| 1601 | |
|---|---|
| set | REACTOME_SARS_COV_2_MODULATES_HOST_TRANSLATION_MACHINERY |
| setSize | 46 |
| pANOVA | 1.41e-05 |
| s.dist | 0.37 |
| p.adjustANOVA | 0.000458 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| RPS12 | 10065 |
| SNRPF | 9718 |
| RPSA | 9598 |
| DDX20 | 9274 |
| GEMIN2 | 9249 |
| RPS18 | 8418 |
| RPS14 | 8367 |
| SNRPD2 | 8144 |
| RPS28 | 8053 |
| SNRPD3 | 7673 |
| RPS10 | 7422 |
| RPS9 | 7239 |
| GEMIN6 | 6871 |
| RPS13 | 6745 |
| RPS21 | 6312 |
| RPS27A | 6223 |
| RPS23 | 6171 |
| RPS2 | 6145 |
| RPS3A | 5876 |
| RPS27L | 5650 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| RPS12 | 10065.0 |
| SNRPF | 9718.0 |
| RPSA | 9598.0 |
| DDX20 | 9274.0 |
| GEMIN2 | 9249.0 |
| RPS18 | 8418.0 |
| RPS14 | 8367.0 |
| SNRPD2 | 8144.0 |
| RPS28 | 8053.0 |
| SNRPD3 | 7673.0 |
| RPS10 | 7422.0 |
| RPS9 | 7239.0 |
| GEMIN6 | 6871.0 |
| RPS13 | 6745.0 |
| RPS21 | 6312.0 |
| RPS27A | 6223.0 |
| RPS23 | 6171.0 |
| RPS2 | 6145.0 |
| RPS3A | 5876.0 |
| RPS27L | 5650.0 |
| RPS16 | 5552.0 |
| FAU | 5376.0 |
| RPS11 | 4468.0 |
| RPS20 | 4174.0 |
| RPS15A | 4169.0 |
| RPS8 | 4117.0 |
| RPS19 | 3558.0 |
| RPS5 | 3408.0 |
| RPS24 | 3357.0 |
| RPS7 | 3333.0 |
| RPS29 | 2812.0 |
| RPS26 | 2583.0 |
| RPS27 | 2232.0 |
| RPS25 | 2059.0 |
| RPS6 | 1237.0 |
| SNRPE | 1062.0 |
| GEMIN7 | -95.0 |
| RPS3 | -935.0 |
| SMN1 | -1491.5 |
| SMN2 | -1491.5 |
| GEMIN4 | -2600.0 |
| RPS15 | -2768.0 |
| SNRPG | -3880.0 |
| GEMIN5 | -5594.0 |
| SNRPB | -6416.0 |
| SNRPD1 | -6773.0 |
Here is the session info with all the versions of packages used.
sessionInfo()## R version 4.3.2 (2023-10-31)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.3 LTS
##
## Matrix products: default
## BLAS: /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so; LAPACK version 3.10.0
##
## locale:
## [1] LC_CTYPE=en_US.UTF-8 LC_NUMERIC=C
## [3] LC_TIME=en_US.UTF-8 LC_COLLATE=en_US.UTF-8
## [5] LC_MONETARY=en_US.UTF-8 LC_MESSAGES=en_US.UTF-8
## [7] LC_PAPER=en_US.UTF-8 LC_NAME=C
## [9] LC_ADDRESS=C LC_TELEPHONE=C
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C
##
## time zone: Etc/UTC
## tzcode source: system (glibc)
##
## attached base packages:
## [1] parallel stats4 stats graphics grDevices utils datasets
## [8] methods base
##
## other attached packages:
## [1] pkgload_1.3.3
## [2] GGally_2.2.0
## [3] ggplot2_3.4.4
## [4] reshape2_1.4.4
## [5] gtools_3.9.5
## [6] tibble_3.2.1
## [7] dplyr_1.1.4
## [8] echarts4r_0.4.5
## [9] png_0.1-8
## [10] gridExtra_2.3
## [11] missMethyl_1.36.0
## [12] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.1
## [13] beeswarm_0.4.0
## [14] kableExtra_1.3.4
## [15] gplots_3.1.3
## [16] mitch_1.15.0
## [17] tictoc_1.2
## [18] HGNChelper_0.8.1
## [19] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [20] IlluminaHumanMethylation450kmanifest_0.4.0
## [21] minfi_1.48.0
## [22] bumphunter_1.44.0
## [23] locfit_1.5-9.8
## [24] iterators_1.0.14
## [25] foreach_1.5.2
## [26] Biostrings_2.70.1
## [27] XVector_0.42.0
## [28] SummarizedExperiment_1.32.0
## [29] Biobase_2.62.0
## [30] MatrixGenerics_1.14.0
## [31] matrixStats_1.2.0
## [32] GenomicRanges_1.54.1
## [33] GenomeInfoDb_1.38.2
## [34] IRanges_2.36.0
## [35] S4Vectors_0.40.2
## [36] BiocGenerics_0.48.1
## [37] eulerr_7.0.0
## [38] limma_3.58.1
##
## loaded via a namespace (and not attached):
## [1] splines_4.3.2 later_1.3.2
## [3] BiocIO_1.12.0 bitops_1.0-7
## [5] filelock_1.0.3 preprocessCore_1.64.0
## [7] XML_3.99-0.16 lifecycle_1.0.4
## [9] lattice_0.22-5 MASS_7.3-60
## [11] base64_2.0.1 scrime_1.3.5
## [13] magrittr_2.0.3 sass_0.4.8
## [15] rmarkdown_2.25 jquerylib_0.1.4
## [17] yaml_2.3.8 httpuv_1.6.13
## [19] doRNG_1.8.6 askpass_1.2.0
## [21] DBI_1.1.3 RColorBrewer_1.1-3
## [23] abind_1.4-5 zlibbioc_1.48.0
## [25] rvest_1.0.3 quadprog_1.5-8
## [27] purrr_1.0.2 RCurl_1.98-1.13
## [29] rappdirs_0.3.3 GenomeInfoDbData_1.2.11
## [31] genefilter_1.84.0 annotate_1.80.0
## [33] svglite_2.1.3 DelayedMatrixStats_1.24.0
## [35] codetools_0.2-19 DelayedArray_0.28.0
## [37] xml2_1.3.6 tidyselect_1.2.0
## [39] beanplot_1.3.1 BiocFileCache_2.10.1
## [41] webshot_0.5.5 illuminaio_0.44.0
## [43] GenomicAlignments_1.38.0 jsonlite_1.8.8
## [45] multtest_2.58.0 ellipsis_0.3.2
## [47] survival_3.5-7 systemfonts_1.0.5
## [49] tools_4.3.2 progress_1.2.3
## [51] Rcpp_1.0.11 glue_1.6.2
## [53] SparseArray_1.2.2 xfun_0.41
## [55] HDF5Array_1.30.0 withr_2.5.2
## [57] fastmap_1.1.1 rhdf5filters_1.14.1
## [59] fansi_1.0.6 openssl_2.1.1
## [61] caTools_1.18.2 digest_0.6.33
## [63] R6_2.5.1 mime_0.12
## [65] colorspace_2.1-0 biomaRt_2.58.0
## [67] RSQLite_2.3.4 utf8_1.2.4
## [69] tidyr_1.3.0 generics_0.1.3
## [71] data.table_1.14.10 rtracklayer_1.62.0
## [73] prettyunits_1.2.0 httr_1.4.7
## [75] htmlwidgets_1.6.4 S4Arrays_1.2.0
## [77] ggstats_0.5.1 pkgconfig_2.0.3
## [79] gtable_0.3.4 blob_1.2.4
## [81] siggenes_1.76.0 htmltools_0.5.7
## [83] scales_1.3.0 rstudioapi_0.15.0
## [85] knitr_1.45 tzdb_0.4.0
## [87] rjson_0.2.21 nlme_3.1-163
## [89] curl_5.2.0 org.Hs.eg.db_3.18.0
## [91] cachem_1.0.8 rhdf5_2.46.1
## [93] stringr_1.5.1 KernSmooth_2.23-22
## [95] AnnotationDbi_1.64.1 restfulr_0.0.15
## [97] GEOquery_2.70.0 pillar_1.9.0
## [99] grid_4.3.2 reshape_0.8.9
## [101] vctrs_0.6.5 promises_1.2.1
## [103] dbplyr_2.4.0 xtable_1.8-4
## [105] evaluate_0.23 readr_2.1.4
## [107] GenomicFeatures_1.54.1 cli_3.6.2
## [109] compiler_4.3.2 Rsamtools_2.18.0
## [111] rlang_1.1.2 crayon_1.5.2
## [113] rngtools_1.5.2 nor1mix_1.3-2
## [115] mclust_6.0.1 plyr_1.8.9
## [117] stringi_1.8.3 viridisLite_0.4.2
## [119] BiocParallel_1.36.0 munsell_0.5.0
## [121] Matrix_1.6-1.1 hms_1.1.3
## [123] sparseMatrixStats_1.14.0 bit64_4.0.5
## [125] Rhdf5lib_1.24.1 KEGGREST_1.42.0
## [127] statmod_1.5.0 shiny_1.8.0
## [129] highr_0.10 memoise_2.0.1
## [131] bslib_0.6.1 bit_4.0.5END of report